title: [Spatial pattern of legionellosis in Spain, 2003-2007].
abstract: OBJECTIVE
  To analyze the spatial pattern of legionellosis in Spain for men and women during the period 2003-2007 and to identify spatial clustering of risk.
  
  
  METHODS
  We identified the spatial pattern of the distribution of legionellosis rates based on calculation of rates by municipality through the direct method. Smoothing of these rates was performed by the Empirical Bayes method for studying the spatial pattern of disease for both sexes. We used Morańs index to analyze spatial autocorrelation rates globally. To calculate local rates, the Local Moran's Index [known as local indicators of spatial association (LISA)], was used to analyze the clusters of municipalities with the highest risk.
  
  
  RESULTS
  After smoothing the risk, the highest rates (over 50 per 100,000 inhabitants) were grouped in the eastern Mediterranean coastal areas and the north of the mainland, as well as in the Mediterranean islands. Moran's index smoothed rates were 0.15 for men and 0.23 for women. The spatial clusters of statistically significant higher rates calculated by the LISA index were distributed in the north and east for both sexes.
  
  
  CONCLUSIONS
  These methods of spatial analysis allow patterns of disease distribution to be identified. All the methods used yielded similar results. These techniques are a complementary tool for epidemiological surveillance of infectious diseases.
authors.affiliation: CIBER en Epidemiología y Salud Pública (CIBERESP), España; Centro Nacional de Epidemiología, Instituto de Salud Carlos III, Madrid, España. dgomez@isciii.es
authors.forename: Diana
authors.initials: D
authors.lastname: Gómez-Barroso
authors.forename: Francisco
authors.initials: F
authors.lastname: Nogareda
authors.forename: Rosa
authors.initials: R
authors.lastname: Cano
authors.forename: Maria Fátima
authors.initials: MF
authors.lastname: Pina
authors.forename: José Luis
authors.initials: JL
authors.lastname: Del Barrio
authors.forename: Fernando
authors.initials: F
authors.lastname: Simon
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D002648:Child; D002675:Child, Preschool; D016000:Cluster Analysis; D004196:Disease Outbreaks; D005260:Female; D006801:Humans; D015994:Incidence; D007223:Infant; D007877:Legionnaires' Disease / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012306:Risk; D017678:Sex Distribution; D013030:Spain / Q000453:epidemiology; D055815:Young Adult