title: Quasi- and pseudo-maximum likelihood estimators for discretely observed continuous-time Markov branching processes.
abstract: This article deals with quasi- and pseudo-likelihood estimation in a class of continuous-time multi-type Markov branching processes observed at discrete points in time. "Conventional" and conditional estimation are discussed for both approaches. We compare their properties and identify situations where they lead to asymptotically equivalent estimators. Both approaches possess robustness properties, and coincide with maximum likelihood estimation in some cases. Quasi-likelihood functions involving only linear combinations of the data may be unable to estimate all model parameters. Remedial measures exist, including the resort either to non-linear functions of the data or to conditioning the moments on appropriate sigma-algebras. The method of pseudo-likelihood may also resolve this issue. We investigate the properties of these approaches in three examples: the pure birth process, the linear birth-and-death process, and a two-type process that generalizes the previous two examples. Simulations studies are conducted to evaluate performance in finite samples.
authors.affiliation: Department of Biostatistics and Computational Biology, University of Rochester Medical Center.
authors.forename: Rui
authors.initials: R
authors.lastname: Chen
authors.forename: Ollivier
authors.initials: O
authors.lastname: Hyrien