title: Migraine prophylaxis: what is new and what we need?
abstract: A wide array of options are now available for migraine prophylaxis. Conventional treatments include beta-blockers, anticonvulsants, antidepressants, calcium antagonists and antiserotoninergic drugs. Emerging medications such as ACE inhibitors, sartans and nutritional supplements are gaining favour for migraine prophylaxis. Botulinum toxin type A is a promising therapeutic tool for chronic migraine. Tonabersat is likely to be a step forward for the treatment of migraine with aura. However, much work is needed to identify predictive clinical features of successful responsiveness and to better define the duration of prophylaxis.
authors.affiliation: Department of Neurological, Motor and Sensorial Sciences, Headache and Pain Unit, IRCCS San Raffaele Pisana, via della Pisana 235, 00163 Rome, Italy. piero.barbanti@sanraffaele.it
authors.forename: P
authors.initials: P
authors.lastname: Barbanti
authors.forename: C
authors.initials: C
authors.lastname: Aurilia
authors.forename: G
authors.initials: G
authors.lastname: Egeo
authors.forename: L
authors.initials: L
authors.lastname: Fofi
mesh_terms: D000700:Analgesics / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D006801:Humans; D008881:Migraine Disorders / Q000188:drug therapy / Q000517:prevention & control*
chemical_list: D000700:Analgesics