title: Vive la différence: biogenesis and evolution of microRNAs in plants and animals.
abstract: MicroRNAs are pervasive in both plants and animals, but many aspects of their biogenesis, function and evolution differ. We reveal how these differences contribute to characteristic features of microRNA evolution in the two kingdoms.
authors.affiliation: Department of Biology, The Pennsylvania State University, 208 Mueller Laboratory, University Park, PA 16802, USA. mja18@psu.edu
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Axtell
authors.forename: Jakub O
authors.initials: JO
authors.lastname: Westholm
authors.forename: Eric C
authors.initials: EC
authors.lastname: Lai
mesh_terms: D000818:Animals; D019143:Evolution, Molecular; D005786:Gene Expression Regulation; D018745:Genome, Plant; D035683:MicroRNAs / Q000096:biosynthesis / Q000235:genetics*; D008957:Models, Genetic; D016366:Open Reading Frames / Q000235:genetics; D010944:Plants / Q000235:genetics*; D034741:RNA, Small Interfering / Q000235:genetics; D022661:RNA, Untranslated / Q000235:genetics
chemical_list: D035683:MicroRNAs; D034741:RNA, Small Interfering; D022661:RNA, Untranslated