title: Pros of priming in the diagnosis of growth hormone deficiency.
abstract: Priming with sex steroids in stimulation tests for the diagnosis of GHD is still under debate. Most of the data on utility of priming during GH stimulation so far seem to support its use in the diagnosis of GHD in childhood. There is a propensity to treat growth retarded children who test subnormally to stimulation tests with GH. However, some studies analyzing the final height or height gain during GH treatment in such children failed to show any improvement in height. This paper summarizes previous studies on priming to analyze the utility of priming as a valid method to better the diagnostic capacity of the test.
authors.affiliation: Department of Pediatric Endocrinology, Hacettepe University Faculty of Medicine, Ankara, Turkey. ngonc@hacettepe.edu.tr
authors.forename: E Nazli
authors.initials: EN
authors.lastname: Gonc
authors.forename: Alev
authors.initials: A
authors.lastname: Ozon
authors.forename: Ayfer
authors.initials: A
authors.lastname: Alikasifoglu
authors.forename: Nurgun
authors.initials: N
authors.lastname: Kandemir
mesh_terms: D000293:Adolescent; D001827:Body Height; D002648:Child; D003940:Diagnostic Techniques, Endocrine / Q000592:standards; D004334:Drug Administration Schedule; D004393:Dwarfism, Pituitary / Q000175:diagnosis* / Q000378:metabolism; D012739:Gonadal Steroid Hormones / Q000008:administration & dosage* / Q000494:pharmacology; D019382:Human Growth Hormone / Q000172:deficiency / Q000378:metabolism; D006801:Humans; D008297:Male; D055571:Secretory Pathway / Q000187:drug effects; D013739:Testosterone / Q000008:administration & dosage
chemical_list: D012739:Gonadal Steroid Hormones; D019382:Human Growth Hormone; D013739:Testosterone