title: Ischemia/reperfusion injury in liver resection: a review of preconditioning methods.
abstract: Ischemic preconditioning is one of the therapeutic interventions aiming at preventing ischemia/reperfusion-related injury. Numerous experimental studies and a few clinical series have shown that during liver resections, ischemic preconditioning is a promising strategy for optimizing the postoperative outcome. Moreover, various types of pharmacological intervention as well as different types of preconditioning, such as remote preconditioning, the use of heat shock, and hyperbaric oxygen, have been developed to attenuate the functional impairment accompanying ischemia/reperfusion injury. This review summarizes the various forms of preconditioning, thus suggesting that close cooperation between surgeons and anesthesiologists paves the way to apply novel strategies to improve the outcome of liver resection.
authors.affiliation: First Department of Anesthesiology, University of Athens, 76 Vassilisis Sofias Avenue, 11528, Athens, Greece.
authors.forename: Kassiani
authors.initials: K
authors.lastname: Theodoraki
authors.forename: Aliki
authors.initials: A
authors.lastname: Tympa
authors.forename: Iosifina
authors.initials: I
authors.lastname: Karmaniolou
authors.forename: Athanassia
authors.initials: A
authors.lastname: Tsaroucha
authors.forename: Nikolaos
authors.initials: N
authors.lastname: Arkadopoulos
authors.forename: Vassilios
authors.initials: V
authors.lastname: Smyrniotis
mesh_terms: D000818:Animals; D006498:Hepatectomy; D006801:Humans; D019194:Ischemic Preconditioning / Q000379:methods*; D008099:Liver / Q000098:blood supply* / Q000503:physiopathology; D015427:Reperfusion Injury / Q000503:physiopathology* / Q000517:prevention & control*