title: [Filter content after carotid angioplasty and stenting: relation to ischemic lesions in diffusion-weighted imaging].
abstract: OBJECTIVE
  To evaluate the relation between the material retrieved from distal filters after carotid angioplasty and stenting and the development of ischemic brain lesions in diffusion-weighted imaging (DWI). To determine the influence of demographic, clinical, and procedural variables in the pathogenesis of emboli and in ischemia after carotid angioplasty and stenting.
  
  
  METHODS
  We submitted the contents of the filters of 76 patients (60 men; mean age, 68.39 years; range, 46-82) who had undergone angioplasty and stenting for severe stenosis of the internal carotid artery for histologic analysis evaluating volume (< 1 λ = 0.001 ml = 1 μl; 1-10 λ; and > 10 λ) and the composition of the particles. All patients underwent DWI before and 24 hours after the procedure; we recorded whether lesions appeared and their number, size, and distribution. We correlated the findings with demographic, clinical, and procedural variables.
  
  
  RESULTS
  Symptoms were present before the procedure in 58 (76.3%) patients. Particles were present in 49 (64.5%) of the filters; most particles (77.5%) were 1 λ with a predominance of fibrin-platelet aggregates, cell remnants, and cholesterol crystals. DWI after the procedure detected lesions in 12 (15.8%) patients. We found no statistically significant correlation between filter contents and lesion detection after the procedure or between filter contents and other variables.
  
  
  CONCLUSIONS
  Ischemia after carotid angioplasty and stenting does not depend solely on the embolic load and its nature. We consider that the lower prevalence of postprocedural lesions in our series compared to others suggests that appropriate patient selection and experience minimize the negative influence of some variables like age in their development.
authors.affiliation: Unidad de Neurorradiología Diagnóstica, Servicio de Radiodiagnóstico, Hospitales Universitarios Virgen del Rocío, Sevilla, España. pilar.pinero.sspa@juntadeandalucia.es
authors.forename: P
authors.initials: P
authors.lastname: Piñero González de la Peña
authors.forename: A
authors.initials: A
authors.lastname: González García
authors.forename: F
authors.initials: F
authors.lastname: Moniche Álvarez
authors.forename: A
authors.initials: A
authors.lastname: Mayol Deyá
authors.forename: J R
authors.initials: JR
authors.lastname: González Marcos
authors.forename: A
authors.initials: A
authors.lastname: Cayuela Domínguez
authors.forename: A
authors.initials: A
authors.lastname: Gil Peralta
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D017130:Angioplasty; D002545:Brain Ischemia / Q000175:diagnosis* / Q000517:prevention & control*; D016893:Carotid Stenosis / Q000628:therapy*; D038524:Diffusion Magnetic Resonance Imaging; D057505:Embolic Protection Devices; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D015607:Stents