title: (R)-3,5-diCF3-SYNPHOS and (R)-p-CF3-SYNPHOS, electron-poor diphosphines for efficient room temperature Rh-catalyzed asymmetric conjugate addition of arylboronic acids.
abstract: Two new atropisomeric electron-poor chiral diphosphine ligand analogues of SYNPHOS were prepared, and their electronic properties are described. These two ligands afforded high performance for the Rh-catalyzed asymmetric 1,4-addition of arylboronic acids to α,β-unsaturated carbonyl compounds at room temperature.
authors.affiliation: Chimie ParisTech, Laboratoire Charles Friedel, UMR CNRS 7223, Paris, France.
authors.forename: Farouk
authors.initials: F
authors.lastname: Berhal
authors.forename: Olivier
authors.initials: O
authors.lastname: Esseiva
authors.forename: Charles-Henri
authors.initials: CH
authors.lastname: Martin
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Tone
authors.forename: Jean-Pierre
authors.initials: JP
authors.lastname: Genet
authors.forename: Tahar
authors.initials: T
authors.lastname: Ayad
authors.forename: Virginie
authors.initials: V
authors.lastname: Ratovelomanana-Vidal