title: Anticoagulant surface of 316 L stainless steel modified by surface-initiated atom transfer radical polymerization.
abstract: Polished 316 L stainless steel (SS) was first treated with air plasma to enhance surface hydrophilicity and was subsequently allowed to react with 2-(4-chlorosulfonylphenyl)ethyltrimethoxysilane to introduce an atom transfer radical polymerization (ATRP) initiator. Accordingly, the surface-initiated atom transfer radical polymerization of polyethylene glycol methacrylate (PEGMA) was carried out on the surface of the modified SS. The grafting progress was monitored by water contact angle measurements, X-ray photoelectron spectroscopy and atomic force microscopy. The polymer thickness as a function different polymerization times was characterized using a step profiler. The anticoagulative properties of the PEGMA modified SS surface were investigated. The results showed enhanced anticoagulative to acid-citrate-dextrose (ACD) blood after grafting PEGMA on the SS surface.
authors.affiliation: Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou 215123, China.
authors.forename: Weihua
authors.initials: W
authors.lastname: Guo
authors.forename: Jian
authors.initials: J
authors.lastname: Zhu
authors.forename: Zhenping
authors.initials: Z
authors.lastname: Cheng
authors.forename: Zhengbiao
authors.initials: Z
authors.lastname: Zhang
authors.forename: Xiulin
authors.initials: X
authors.lastname: Zhu
mesh_terms: D000925:Anticoagulants / Q000737:chemistry* / Q000494:pharmacology*; D057927:Hydrophobic and Hydrophilic Interactions; D008689:Methacrylates / Q000737:chemistry* / Q000494:pharmacology*; D018625:Microscopy, Atomic Force; D056951:Photoelectron Spectroscopy; D011092:Polyethylene Glycols / Q000737:chemistry* / Q000494:pharmacology*; D013193:Stainless Steel / Q000737:chemistry*; D013499:Surface Properties
chemical_list: D000925:Anticoagulants; D008689:Methacrylates; C524499:polyethylene glycol methacrylate; D013193:Stainless Steel; D011092:Polyethylene Glycols