title: Synthesis and antifungal activities of natural and synthetic biflavonoids.
abstract: The synthesis of some natural and synthetic biflavonoids was performed in good overall yields starting from readily available materials via high yielding aldol and Ullmann condensations. Some of these compounds, especially bichalcones, display an interesting activity against fungi, higher than that of the corresponding monomers.
authors.affiliation: Departamento de Química Orgánica, Facultad de Ciencias, Universidad de la República, Montevideo, Uruguay.
authors.forename: Gabriel
authors.initials: G
authors.lastname: Sagrera
authors.forename: Ana
authors.initials: A
authors.lastname: Bertucci
authors.forename: Alvaro
authors.initials: A
authors.lastname: Vazquez
authors.forename: Gustavo
authors.initials: G
authors.lastname: Seoane
mesh_terms: D000935:Antifungal Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D044946:Biflavonoids / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D005658:Fungi / Q000187:drug effects*; D006801:Humans; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D009181:Mycoses / Q000188:drug therapy
chemical_list: D000935:Antifungal Agents; D044946:Biflavonoids