title: Topical retinoids for pigmented skin.
abstract: Topical retinoids are an important class of drugs for treating several dermatoses occurring more frequently in patients with pigmented skin, such as melasma, post-inflammatory hyperpigmentation, pseudofolliculits barbae and keloids. They also play a role in managing acne, psoriasis, photoaging, cutaneous T-cell lymphoma, Kaposi sarcoma and disorder of hyperkeratosis in this demographic as well. In general, topical retinoids are well tolerated in pigmented skins. There is little evidence to suggest that patients with darker skin are at increased risk of irritation. However, retinoid dermatitis can induce post-inflammatory hyperpigmentation and attempts should be made to reduce its occurrence by modifying treatment regimens in patients with pigmented skins.
authors.affiliation: Department of Dermatology, Howard University College of Medicine, Washington, DC 20060, USA.
authors.forename: Aanand N
authors.initials: AN
authors.lastname: Geria
authors.forename: Christina N
authors.initials: CN
authors.lastname: Lawson
authors.forename: Rebat M
authors.initials: RM
authors.lastname: Halder
mesh_terms: D000279:Administration, Cutaneous; D006801:Humans; D017495:Hyperpigmentation / Q000188:drug therapy / Q000473:pathology; D017410:Practice Guidelines as Topic; D012176:Retinoids / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D012871:Skin Diseases / Q000188:drug therapy* / Q000473:pathology; D012880:Skin Pigmentation
chemical_list: D012176:Retinoids