title: The effects of impulse noise on the epithelial cells of the choroid plexus.
abstract: OBJECTIVE
  The aim of this study was to investigate the effects of impulse noise on the epithelial cells of the choroid plexus.
  
  
  METHODS
  Forty Sprague Dawley rats were used and divided into the 2 groups as control and study groups. In the control group, the rats did not suffer noise injury. The rats were exposed to impulse noise at 20 minute durations at 10 times each day for one month in study group. Then, the rats were sacrificed and the choroid plexuses were examined histologically. The number of cells was counted and the cells were analyzed.
  
  
  RESULTS
  There were clear signs of nuclear condensation and cell body shrinkage, suggesting the presence of apoptosis. Severe desquamation of villus and the cell loss were observed in the study group. The numbers of the normal cells decreased, and the number of apoptotic cells increased significantly (p < 0.05).
  
  
  CONCLUSIONS
  Impulse noise causes apoptotic death of epithelial cells in the choroid plexus, decrease the normal cells and increase the apoptotic cells.
authors.affiliation: M.H. Luleburgaz State Hospital, Department of Neurosurgery, Kirklareli / Luleburgaz, Turkey.
authors.forename: Mehmet Dumlu
authors.initials: MD
authors.lastname: Aydin
authors.forename: Mehmet Kaan
authors.initials: MK
authors.lastname: Ungoren
authors.forename: Nazan
authors.initials: N
authors.lastname: Aydin
authors.forename: Zekai
authors.initials: Z
authors.lastname: Halici
authors.forename: Arif
authors.initials: A
authors.lastname: Onder
authors.forename: Cemal
authors.initials: C
authors.lastname: Gundogdu
authors.forename: Yusuf
authors.initials: Y
authors.lastname: Izci
mesh_terms: D000161:Acoustic Stimulation / Q000379:methods; D000818:Animals; D017209:Apoptosis; D001284:Atrophy; D002452:Cell Count; D002831:Choroid Plexus / Q000293:injuries* / Q000473:pathology*; D004847:Epithelial Cells / Q000473:pathology*; D005260:Female; D008297:Male; D008871:Microvilli / Q000473:pathology; D009146:Music; D009622:Noise / Q000009:adverse effects*; D051381:Rats; D017207:Rats, Sprague-Dawley