title: Allergen compatibilities in extract mixtures.
abstract: Stability studies with a few well-characterized allergen extracts have yielded useful information about the shelf-life of these products stored under various conditions. The development of validated stability-indicating tests and their clinical verification remains a fundamental challenge for extending this information to cover more products. This challenge becomes even greater for evaluations of more complex, multiextract mixtures that are used in clinical practice. Thus, the current approach for developing guidelines for extract expiration dating practices must rely on extrapolations of data obtained from a few well-controlled studies.
authors.affiliation: Research and Development, Greer Laboratories, Inc, 639 Nuway Circle, Lenoir, NC 28645, USA. esch@greerlabs.com
authors.forename: Robert E
authors.initials: RE
authors.lastname: Esch
authors.forename: Thomas J
authors.initials: TJ
authors.lastname: Grier
mesh_terms: D000485:Allergens / Q000276:immunology* / Q000627:therapeutic use; D045424:Complex Mixtures / Q000276:immunology* / Q000627:therapeutic use; D003888:Desensitization, Immunologic; D004338:Drug Combinations; D004355:Drug Stability; D006801:Humans; D006967:Hypersensitivity / Q000628:therapy
chemical_list: D000485:Allergens; D045424:Complex Mixtures; D004338:Drug Combinations