title: Amyloidosis in a child with leucocyte adhesion deficiency type-1: an unusual association.
abstract: Leucocyte adhesion deficiency type I (LAD I) is a rare autosomal recessive disorder of leucocyte function, characterized by delayed separation of the umblical cord, recurrent bacterial and fungal infections, defective wound healing and impressive constant blood neutrophilia. The authors report a child with genetic diagnosis of leucocyte adhesion deficiency (LAD) type I, who succumbed to his illness and developed amyloidosis preterminally. To the best of author's knowledge this is the first case of leucocyte adhesion deficiency type I associated with amyloidosis among the human LAD cases worldwide.
authors.affiliation: Allergy-Immunology Unit, Department of Pediatrics, Advanced Pediatrics Center, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India.
authors.forename: Amit
authors.initials: A
authors.lastname: Rawat
authors.forename: Surjit
authors.initials: S
authors.lastname: Singh
authors.forename: Dhrubajyoti
authors.initials: D
authors.lastname: Sharma
authors.forename: Deepti
authors.initials: D
authors.lastname: Suri
authors.forename: Arvind
authors.initials: A
authors.lastname: Rajwanshi
authors.forename: Amos
authors.initials: A
authors.lastname: Etzioni
mesh_terms: D000686:Amyloidosis / Q000150:complications* / Q000175:diagnosis; D002675:Child, Preschool; D017809:Fatal Outcome; D006801:Humans; D018370:Leukocyte-Adhesion Deficiency Syndrome / Q000150:complications* / Q000235:genetics; D008297:Male