title: Recovery of preoptic-anterior hypothalamic functions after transplantation.
abstract: Kainic acid lesion of the medial preoptic area resulted in the impairment of the thermoregulation and disruption of the reproductive cycle in female rats. The preoptic-anterior hypothalamic area from fetal donor was transplanted into the lesioned area ofthe host. After transplantation, these animals showed signs of estrus cyclicity and a recovery in basal temperature towards normal. They also showed a reduced shift of body temperature on exposure to a hot environment. Thus the female rats, which received transplantation, showed some degree of recovery of functions which were disrupted by kainic acid lesions.
authors.affiliation: Department of Physiology, All India Institute of Medical Sciences, New Delhi 110029 (India).
authors.forename: S
authors.initials: S
authors.lastname: Verma
authors.forename: V M
authors.initials: VM
authors.lastname: Kumar
authors.forename: G
authors.initials: G
authors.lastname: Gopinath
authors.forename: R
authors.initials: R
authors.lastname: Sharma
authors.forename: P N
authors.initials: PN
authors.lastname: Tandon