title: Simultaneous non-functioning neuroendocrine carcinoma of the pancreas and extra-hepatic cholangiocarcinoma. A case of early diagnosis and favorable post-surgical outcome.
abstract: BACKGROUND
  Thanks to the wide use of diagnostic imaging modalities, multiple primary malignancies are being diagnosed more frequently and different associations of malignancies have been reported in this setting.
  
  
  METHODS
  In this paper, we describe the case of a patient with non-functioning well-differentiated neuroendocrine carcinoma of the head of the pancreas associated with extra-hepatic cholangiocarcinoma, in which an early diagnosis using magnetic resonance imaging allowed a good outcome.
  
  
  CONCLUSIONS
  The simultaneous association of neuroendocrine pancreatic tumors and cholangiocarcinoma has not yet been described; however, this association should be considered and, due to the high contrast of magnetic resonance imaging, this technique is recommended in such patient in order to reach an accurate diagnosis.
authors.affiliation: Department of Biomorphological and Functional Sciences (DSBMF), University Federico II of Napoli (UNINA), Naples, Italy. simone.maurea@unina.it
authors.forename: Simone
authors.initials: S
authors.lastname: Maurea
authors.forename: Antonio
authors.initials: A
authors.lastname: Corvino
authors.forename: Massimo
authors.initials: M
authors.lastname: Imbriaco
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Avitabile
authors.forename: Pierpaolo
authors.initials: P
authors.lastname: Mainenti
authors.forename: Luigi
authors.initials: L
authors.lastname: Camera
authors.forename: Gennaro
authors.initials: G
authors.lastname: Galizia
authors.forename: Marco
authors.initials: M
authors.lastname: Salvatore
mesh_terms: D001650:Bile Duct Neoplasms / Q000175:diagnosis* / Q000601:surgery; D017734:Bile Ducts, Extrahepatic; D018278:Carcinoma, Neuroendocrine / Q000175:diagnosis* / Q000601:surgery; D018281:Cholangiocarcinoma / Q000175:diagnosis* / Q000601:surgery; D003937:Diagnosis, Differential; D042241:Early Diagnosis; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis* / Q000601:surgery; D010190:Pancreatic Neoplasms / Q000175:diagnosis* / Q000601:surgery; D016896:Treatment Outcome