title: Resolution of syringohydromyelia with targeted CT-guided epidural blood patching.
abstract: In the scientific literature, syringohydromyelia has only rarely been reported in association with spontaneous intracranial hypotension. Management of the syringohydromyelia in these patients has heretofore involved relatively invasive surgical procedures. The authors report the first case of syringohydromyelia in the setting of intracranial hypotension successfully treated with CT-guided epidural blood patches. This case is important in that it represents a potential minimally invasive treatment strategy. Furthermore, the case also highlights the need to consider spontaneous intracranial hypotension when clinically appropriate as a cause of syrinx in patients with cerebellar tonsillar ectopia, in whom the lesion might otherwise be misclassified as a Chiari I malformation. Finally, the responses to the various attempted treatments offer insight into the pathophysiology of this syringohydromyelia, which may differ from classical models of syrinx formation.
authors.affiliation: Department of Radiology, Duke University Medical Center, Durham, North Carolina, USA. peter.kranz@duke.edu
authors.forename: Peter G
authors.initials: PG
authors.lastname: Kranz
authors.forename: Ronald J
authors.initials: RJ
authors.lastname: Viola
authors.forename: Linda
authors.initials: L
authors.lastname: Gray
mesh_terms: D017217:Blood Patch, Epidural / Q000379:methods*; D005260:Female; D006801:Humans; D019585:Intracranial Hypotension / Q000150:complications* / Q000628:therapy; D008875:Middle Aged; D013595:Syringomyelia / Q000150:complications / Q000628:therapy*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome