title: Primary extranodal lymphomas of Waldeyer's ring, stage IE and IIE.
abstract: We reviewed 45 cases of Waldeyer's ring lymphomas (25 stage IE, 20 IIE): 73% had high-grade histology according to Kiel's classification. Fourteen patients received radiotherapy alone and 31 chemotherapy, combined with radiotherapy in 28. Complete remission rate was 95% and relapse rate 32%. At 8 years overall disease-related survival (DRS) and event-free survival (EFS) were 69% and 57% respectively. Combined treatment provided both significantly better DRS (82% vs 42%) and EFS (76% vs 25%) than radiotherapy alone. Most of the patients with high-grade histology (26/33) received the combined treatment and this subgroup achieved a long-term EFS of 78%. Both DRS and EFS were also significantly longer in patients under 60. At multivariate analysis favorable prognostic factors were lower age for DRS and combined treatment for EFS.
authors.affiliation: OSPED CIVILE,DIV RADIOTERAPIA,I-37126 VERONA,ITALY. UNIV VERONA,CATTEDRA ONCOL MED,I-37100 VERONA,ITALY. UNIV VERONA,CATTEDRA EMATOL,I-37100 VERONA,ITALY. UNIV VERONA,CATTEDRA STAT MED,I-37100 VERONA,ITALY.
authors.forename: F
authors.initials: F
authors.lastname: Pasini
authors.forename: M
authors.initials: M
authors.lastname: Bassetto
authors.forename: G
authors.initials: G
authors.lastname: Todeschini
authors.forename: A
authors.initials: A
authors.lastname: Dimarco
authors.forename: G
authors.initials: G
authors.lastname: Verlato
authors.forename: F
authors.initials: F
authors.lastname: Scognamiglio
authors.forename: R
authors.initials: R
authors.lastname: Zanotti
authors.forename: D
authors.initials: D
authors.lastname: Veneri
authors.forename: G
authors.initials: G
authors.lastname: Cetto
authors.forename: A
authors.initials: A
authors.lastname: Ambrosetti