title: Open vessel mode microwave-assisted synthesis of 2-oxazolines from carboxylic acids.
abstract: Microwave-assisted synthesis of 2-oxazolines from carboxylic acids using the open vessel technique is described. This efficient method involves direct condensation of carboxylic acids with excess 2-amino-2-methyl-1-propanol at 170 °C to give the corresponding 2-oxazolines in moderate to excellent yields.
authors.affiliation: Center for Drug Discovery, Northeastern University, 360 Huntington Avenue, 116 Mugar Life Sciences Building, Boston, MA, 02115, USA.
authors.forename: Rishi
authors.initials: R
authors.lastname: Sharma
authors.forename: Subramanian K
authors.initials: SK
authors.lastname: Vadivel
authors.forename: Richard I
authors.initials: RI
authors.lastname: Duclos
authors.forename: Alexandros
authors.initials: A
authors.lastname: Makriyannis