title: Soft tissue augmentation by autologous cultured fibroblasts transplantation for treatment of wrinkles and scars: a case series of 20 patients.
abstract: BACKGROUND
  There are many filler agents for augmentation of static wrinkles and atrophic scars from synthetic, bio-synthetic, cadaver, animal and human sources.
  
  
  METHODS
  The current study presents 20 patients whose facial wrinkles and lines were treated by transplantation of autologous cultured fibroblasts. The fibroblast nature of cells was confirmed by immune-staining and flow cytometry.
  
  
  RESULTS
  The mean of improvement for this procedure at the 6 month follow up was 41%.
  
  
  CONCLUSIONS
  In conclusion autologous fibroblast transplantation can be an effective procedure for correction of wrinkles and atrophic scars.
authors.affiliation: Dermatologist, Associate Professor of Dermatology, Head of Skin Diseases and Leishmaniasis Research Center (Sedigheh Tahereh), Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Mohammad Ali
authors.initials: MA
authors.lastname: Nilforoushzadeh
authors.forename: Amir Hossein
authors.initials: AH
authors.lastname: Siadat
authors.forename: Mojgan
authors.initials: M
authors.lastname: Arianrad
authors.forename: Fariba
authors.initials: F
authors.lastname: Moulavi
authors.forename: Elahe Haft
authors.initials: EH
authors.lastname: Baradaran
authors.forename: Mohhamad Hossein Nasr
authors.initials: MH
authors.lastname: Esfahani