title: A copper(II) complex as an intermediate of copper(I)-catalyzed C-N cross coupling of N-phenylaniline with aryl halide by in situ ESI-MS study.
abstract: Complexes [Cu(NPh(2))(2)](-), [Cu(NPh(2))I](-) and K[Cu(phen)(NPh(2)) (p-tolyl)](+) were observed by in situ electrospray ionization mass spectrometry (ESI-MS) analysis of the copper(I)-catalyzed C-N coupling reaction under the catalytic reaction condition indicating that they are intermediates in the reaction. A catalytic cycle composed of a free radical path and a 2e oxidative addition path is proposed based on these observations.
authors.affiliation: Institute of Chemistry, Academia Sinica, Taipei 115, Taiwan, Republic of China.
authors.forename: Chia-Kai
authors.initials: CK
authors.lastname: Tseng
authors.forename: Mei-Chun
authors.initials: MC
authors.lastname: Tseng
authors.forename: Chien-Chung
authors.initials: CC
authors.lastname: Han
authors.forename: Shin-Guang
authors.initials: SG
authors.lastname: Shyu