title: Diagnosis and treatment of azoospermia resulting from testicular sarcoidosis.
abstract: Genitourinary sarcoidosis is uncommon, with only rare documented cases of  testicular involvement reported. We detail the case of a 37-year-old male who  initially presented for azoospermia and secondary infertility. A testicular  biopsy revealed nonnecrotizing granulomas and a chest x-ray identified  perihilar lymphadenopathy and granulomatous lung nodules. A corticosteroid  regimen was administered, and routine semen analyses were conducted.  Significant improvements were noted after prednisone treatments. A successful  in vivo fertilization was obtained. This is the first known case of testicular  sarcoidosis diagnosed during investigations into azoospermia and secondary  infertility which, after treatment with corticosteroids, resulted in natural  fertilization.
authors.affiliation: McMaster Institute of Urology, St Joseph's Hospital, 50 Charlton Ave E, Hamilton, Ontario L8N 4A6, Canada. kovacj4@mcmaster.ca
authors.forename: Jason R
authors.initials: JR
authors.lastname: Kovac
authors.forename: Diane
authors.initials: D
authors.lastname: Flood
authors.forename: J Brendan
authors.initials: JB
authors.lastname: Mullen
authors.forename: Marc Anthony
authors.initials: MA
authors.lastname: Fischer
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use*; D000328:Adult; D053713:Azoospermia / Q000175:diagnosis* / Q000188:drug therapy* / Q000209:etiology; D001706:Biopsy; D005306:Fertilization / Q000187:drug effects*; D006801:Humans; D008297:Male; D020127:Recovery of Function; D012507:Sarcoidosis / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy*; D055101:Semen Analysis; D013091:Spermatogenesis / Q000187:drug effects; D013733:Testicular Diseases / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy*; D016896:Treatment Outcome
chemical_list: D000305:Adrenal Cortex Hormones