title: Manifestations of small bowel disease in pediatric Crohn's disease on magnetic resonance enterography.
abstract: BACKGROUND
  We report the manifestations of Crohn's disease (CD) observed on magnetic resonance enterography (MRE) in a pediatric population at the time of CD diagnosis.
  
  
  METHODS
  MRE of 95 consecutive pediatric patients with inflammatory bowel disease (IBD) examined in 2006-2009 were retrospectively analyzed, with documentation of findings based on type and location of the small bowel (SB) disease.
  
  
  RESULTS
  In all, 51 were boys and 44 girls. 54 had CD, 31 non-CD IBD, and 10 no IBD. The most common site of SB involvement in CD was the terminal ileum seen in 29 (53.7%) patients, followed by ileum in 10 (18.5%) and jejunum in 9 (16.7%) patients. Solitary jejunal inflammation (3.7%), SB stenoses (1.9%), fistula formation (0.95%), and abscess (0.95%) were much less common. Perienteric lymphadenopathy was seen in 30 (55.6%) patients and fatty proliferation in 9 (16.7%). The most common manifestation of SB inflammation was increased contrast enhancement of bowel wall (93.5%), thickening of the bowel wall (90.3%), and derangement of bowel shape with saccular formations (25.8%).
  
  
  CONCLUSIONS
  MRE in the pediatric population often demonstrates increased contrast uptake, bowel wall thickening, and perienteral lymphadenopathy in CD. More chronic small bowel changes seen commonly in adults and solitary jejunal involvements are less commonly seen.
authors.affiliation: Uppsala University, Department of Oncology, Radiology and Clinical Immunology, Section of Radiology, Uppsala University Hospital, Uppsala. Michael.torkzad@radiol.uu.se
authors.forename: Michael R
authors.initials: MR
authors.lastname: Torkzad
authors.forename: Ulla
authors.initials: U
authors.lastname: Ullberg
authors.forename: Niklas
authors.initials: N
authors.lastname: Nyström
authors.forename: Lennart
authors.initials: L
authors.lastname: Blomqvist
authors.forename: Per
authors.initials: P
authors.lastname: Hellström
authors.forename: Ulrika L
authors.initials: UL
authors.lastname: Fagerberg
mesh_terms: D018784:Abdominal Abscess / Q000209:etiology; D000293:Adolescent; D002648:Child; D003251:Constriction, Pathologic / Q000209:etiology; D003424:Crohn Disease / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D016099:Endoscopy, Gastrointestinal; D005260:Female; D006801:Humans; D007077:Ileal Diseases / Q000175:diagnosis* / Q000473:pathology; D007412:Intestinal Fistula / Q000209:etiology; D007579:Jejunal Diseases / Q000175:diagnosis* / Q000473:pathology; D008206:Lymphatic Diseases / Q000209:etiology; D008279:Magnetic Resonance Imaging; D008297:Male; D012189:Retrospective Studies