title: Evaluation of the inflammatory response to two different intensities of exercise in individuals with heart failure.
abstract: The aim of this study is to compare the response of interleukin-6 (IL-6) and soluble tumor necrosis factor alpha receptor 1 (s-TNFr1) to two submaximal intensities of exercise in individuals with heart failure (HF). Thirty-two HF individuals aged 45.53 ± 9.41 years, classes II and III of the New York Heart Association (NYHA) classification underwent two sessions of exercise at low and moderate intensities with blood analysis at baseline, exercise and after exercise. The differences were evaluated by Friedman test and factorial ANOVA. Alpha = 5% was considered. No difference in IL-6 was detected for low intensity. At moderate intensity, there was a significant increase after exercise. The s-TNFr1 increased in moderate-intensity exercise and went back to baseline levels after it. A session of moderate-intensity exercise is better than low-intensity exercise at promoting positive immediate inflammatory responses in individuals with HF class II and III of the NYHA.
authors.affiliation: Physical Therapy Department, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil. d.fisio@ig.com.br
authors.forename: Danielle Aparecida Gomes
authors.initials: DA
authors.lastname: Pereira
authors.forename: Giane Amorim
authors.initials: GA
authors.lastname: Ribeiro-Samora
authors.forename: Danielle Soares Rocha
authors.initials: DS
authors.lastname: Vieira
authors.forename: Leani Souza Máximo
authors.initials: LS
authors.lastname: Pereira
authors.forename: Fernanda Matos
authors.initials: FM
authors.lastname: Coelho
authors.forename: Verônica Franco
authors.initials: VF
authors.lastname: Parreira
authors.forename: Maria da Consolação Vieira
authors.initials: Mda C
authors.lastname: Moreira
authors.forename: Maria Clara Noman
authors.initials: MC
authors.lastname: Alencar
authors.forename: Raquel Rodrigues
authors.initials: RR
authors.lastname: Britto
mesh_terms: D000328:Adult; D015444:Exercise; D005080:Exercise Test; D005260:Female; D006333:Heart Failure / Q000276:immunology*; D006801:Humans; D007249:Inflammation; D015850:Interleukin-6 / Q000097:blood*; D008297:Male; D008875:Middle Aged; D047888:Receptors, Tumor Necrosis Factor, Type I / Q000097:blood*
chemical_list: D015850:Interleukin-6; D047888:Receptors, Tumor Necrosis Factor, Type I