title: Diffuse in-stent restenosis of CYPHER® stent due to hypersensitivity reaction confirmed by pathohistological findings.
abstract: The use of drug-eluting stents (DES) reduces the risk of repeat revascularization without increase of death and myocardial infarction compared to standard bare metal stents. However, in-stent restenosis (ISR) after DES implantation still occurs. Here, we report a rare case with a diffuse ISR after CYPHER® stent implantation because of chronic inflammation and hypersensitivity reactions, confirmed by pathohistological findings.
authors.affiliation: Department of Cardiology, Fukuoka Wajiro Hospital, 2-2-75 Wajirogaoka, Higashi-ku, Fukuoka, 811-0213, Japan. yotsuka@f-wajirohp.jp
authors.forename: Yoritaka
authors.initials: Y
authors.lastname: Otsuka
authors.forename: Masanori
authors.initials: M
authors.lastname: Nakamura
authors.forename: Nobuaki
authors.initials: N
authors.lastname: Kokubu
authors.forename: Akiko
authors.initials: A
authors.lastname: Tonooka
authors.forename: Katsumi
authors.initials: K
authors.lastname: Inoue
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Higami
mesh_terms: D015906:Angioplasty, Balloon, Coronary / Q000009:adverse effects* / Q000295:instrumentation; D017023:Coronary Angiography; D054059:Coronary Occlusion / Q000000981:diagnostic imaging / Q000628:therapy*; D023903:Coronary Restenosis / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D054855:Drug-Eluting Stents; D004691:Endarterectomy; D006801:Humans; D006967:Hypersensitivity / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D007249:Inflammation / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D008297:Male; D008875:Middle Aged; D011474:Prosthesis Design; D016896:Treatment Outcome