title: (2R*,4S*)-2-(pyridin-3-yl)-2,3,4,5-tetrahydro-1H-1-benzazepin-4-ol: a three-dimensional framework built from O-H···N, C-H···O and C-H···π(arene) hydrogen bonds.
abstract: The title compound, C(15)H(16)N(2)O, crystallizes in the space group P2(1)2(1)2(1) with Z' = 1. The seven-membered ring adopts a chair-type conformation with the hydroxy and pyridyl substituents in equatorial sites. Molecules are linked into a three-dimensional framework structure by a combination of O-H···N, C-H···O and C-H···π(arene) hydrogen bonds, but N-H···O and N-H···π(arene) interactions are absent from the structure. Comparisons are made with some related compounds.
authors.affiliation: Laboratorio de Síntesis Orgánica, Escuela de Química, Universidad Industrial de Santander, AA 678 Bucaramanga, Colombia.
authors.forename: Sandra L
authors.initials: SL
authors.lastname: Gómez
authors.forename: Alirio
authors.initials: A
authors.lastname: Palma
authors.forename: Justo
authors.initials: J
authors.lastname: Cobo
authors.forename: Christopher
authors.initials: C
authors.lastname: Glidewell
mesh_terms: D001552:Benzazepines / Q000737:chemistry*; D018360:Crystallography, X-Ray; D006860:Hydrogen Bonding; D008968:Molecular Conformation; D015394:Molecular Structure; D011725:Pyridines / Q000737:chemistry*
chemical_list: C559605:(2R*,4S*)-2-(pyridin-3-yl)-2,3,4,5-tetrahydro-1H-1-benzazepin-4-ol; D001552:Benzazepines; D011725:Pyridines