title: A unified treatment of the probability of fixation when population size and the strength of selection change over time.
abstract: The fixation probability is determined when population size and selection change over time and differs from Kimura's result, with long-term implications for a population. It is found that changes in population size are not equivalent to the corresponding changes in selection and can result in less drift than anticipated.
authors.affiliation: Centre for Computational Systems Biology, Fudan University, Shanghai 200433, People's Republic of China. dwaxman.biology@gmail.com
authors.forename: D
authors.initials: D
authors.lastname: Waxman
mesh_terms: D000465:Algorithms; D000483:Alleles; D000818:Animals; D019143:Evolution, Molecular; D005828:Genetics, Population; D006801:Humans; D008957:Models, Genetic; D011156:Population Density; D011336:Probability; D012641:Selection, Genetic; D013997:Time Factors