title: [Studies on the extraction of volatile oil from Thymus marschallianus and preparation of its beta-CD inclusion compounds].
abstract: OBJECTIVE
  To study the optimum conditions for the extraction of volatile oil from Thymus marschallianus and the preparation of its beta-CD inclusion compounds.
  
  
  METHODS
  The study was carried out with single factor and orthogonal design. With the percentages of extracted volatile oil of Thymus marschallianus as the target marker we selected the optimum conditions for extracting the volatile oil. The ration of inclusion and the oiling-bearing from the inclusion as the target marker was to optimize the conditions for including the oils with beta-CD.
  
  
  RESULTS
  The optimized extraction conditions were as follows: the water was 12 times of the herbs in weight, Thymus marschallianus should be extracted for 4 hours after soaked 0.5 hours with water. The optimized inclusion conditions were as follows: applying the saturated aqueous solution method, the proportion of oil and beta-CD was 1 mL: 8 g, the temperature and time were 60 degrees C and 60 minutes, respectively.
  
  
  CONCLUSIONS
  The established process can be used for the extraction and the inclusion of volatile oil from Thymus marschallianus with its high ration of oil and the economic cost.
authors.affiliation: Affiliated Traditional Medical Hospital of Xinjiang Medical University, Urumqi 830000, China. zzhhyy2583@126.com
authors.forename: Hai-Ying
authors.initials: HY
authors.lastname: Zhang
authors.forename: Wei
authors.initials: W
authors.lastname: Li
mesh_terms: D004337:Drug Carriers; D004355:Drug Stability; D009822:Oils, Volatile / Q000008:administration & dosage / Q000302:isolation & purification*; D010946:Plants, Medicinal / Q000737:chemistry*; D013056:Spectrophotometry, Ultraviolet; D013678:Technology, Pharmaceutical / Q000379:methods*; D013696:Temperature; D046930:Thymus Plant / Q000737:chemistry*; D013997:Time Factors; D014867:Water; D047392:beta-Cyclodextrins
chemical_list: D004337:Drug Carriers; D009822:Oils, Volatile; D047392:beta-Cyclodextrins; D014867:Water