title: [Gingival hyperplasia as side effect of the calcium channel blocker amlodipine].
abstract: Medically induced gingival overgrowth is one of the major side effects of phenytoine, cyclosporine A and the channel blocker Nifedipine and it is well documented in various studies and case series. Recently an alternative channel blocker, Amlodipine, has been implemented into the clinical treatment of cardiovascular diseases. By means of a clinical case presentation it was shown that Amlodipine is able to induce gingival overgrowth in the oral cavity as well. Additionally, the causes of Amlodipine-induced gingival hyperplasia are critically discussed and several options of therapy modalities presented.
authors.affiliation: Gemeinschaftspraxis Hradschin 14 Dres. Altekrüger, Heinert, Preussner und Winkler, Hradschin 14, D-08523 Plauen.
authors.forename: Knut
authors.initials: K
authors.lastname: Breitung
authors.forename: Torsten W
authors.initials: TW
authors.lastname: Remmerbach
mesh_terms: D000369:Aged, 80 and over; D017311:Amlodipine / Q000009:adverse effects*; D000959:Antihypertensive Agents / Q000009:adverse effects*; D002121:Calcium Channel Blockers / Q000009:adverse effects*; D005260:Female; D005885:Gingival Hyperplasia / Q000139:chemically induced*; D006333:Heart Failure / Q000188:drug therapy; D006801:Humans; D006973:Hypertension / Q000188:drug therapy
chemical_list: D000959:Antihypertensive Agents; D002121:Calcium Channel Blockers; D017311:Amlodipine