title: Case report: doxycycline instillation used to treat a high-output lymphatic fistula secondary to needle puncture.
abstract: Previous reports have documented the use of doxycycline as a sclerosing agent in the treatment of recurrent pleural effusion and pneumothoracies. However, little is currently known of its use in the closure of lymphatic fistulae. This paper presents a case in which an infusion of doxycycline was used in a patient who had developed the unusual complication of a high-output lymphatic fistula, following a femoral needle puncture. As no standard of care has been established in the treatment of this problem, we embarked on a minimally-invasive course of action, using doxycycline as a sclerosing agent. We found this treatment to be effective, with no complications.
authors.affiliation: Division of Vascular and Endovascular Surgery, Department of Surgery, Staten Island University Hospital, Staten Island, New York, USA. kgoraya@yahoo.com
authors.forename: K
authors.initials: K
authors.lastname: Singh
authors.forename: M L
authors.initials: ML
authors.lastname: Wang
authors.forename: V
authors.initials: V
authors.lastname: Rubinshteyn
authors.forename: C
authors.initials: C
authors.lastname: Sticco
authors.forename: J
authors.initials: J
authors.lastname: Deitch
mesh_terms: D002406:Catheterization, Peripheral / Q000009:adverse effects*; D004318:Doxycycline / Q000627:therapeutic use*; D005260:Female; D005268:Femoral Vein; D005402:Fistula / Q000188:drug therapy*; D006801:Humans; D007322:Instillation, Drug; D008206:Lymphatic Diseases / Q000188:drug therapy*; D008875:Middle Aged; D012597:Sclerosing Solutions / Q000627:therapeutic use*
chemical_list: D012597:Sclerosing Solutions; D004318:Doxycycline