title: Contrast-induced nephropathy risk due to emergency contrast-enhanced computed tomography.
abstract: OBJECTIVE
  In this study, we aimed to compare serum creatinine, blood urea, and glomerular filtration rate (GFR) levels of patients at baseline and 48 h after the administration of radiocontrast agent in the emergency department.
  
  
  METHODS
  We prospectively enrolled 114 patients who underwent contrast-enhanced computed tomography scan and had a baseline creatinine level of 1.5 mg/dl or less. Serum creatinine and blood urea levels were measured at baseline and 48 h after the administration of radiocontrast agent. GFR and Mehran risk score were calculated at baseline and 48 h after the administration of radiocontrast agent.
  
  
  RESULTS
  Baseline mean serum creatinine was 1.03±0.25 mg/dl. Forty-eight hours after the administration of radiocontrast agent, mean serum creatinine was 1.04±0.31 mg/dl, baseline mean blood urea was 8.14±4.04 mmol/l, mean blood urea was 8.42±4.42 mmol/l, baseline mean GFR was 76.74±27.08 ml/min, and mean GFR was 77.21±27.92 ml/min. There were no significant differences between baseline and 48 h after the administration of radiocontrast agent serum creatinine, blood urea levels, and GFR (P>0.05).
  
  
  CONCLUSIONS
  There was no statistically significant difference between basal and 48 h after the administration of radiocontrast agent serum creatinine and GFR levels of patients who were enrolled in this study. Results had shown that administration of intravenous radiocontrast agent (≤100 ml) for emergency imaging in the emergency department did not produce a risk for contrast-induced nephropathy in patients with serum creatinine levels of 1.5 mg/dl or less.
authors.affiliation: Department of Emergency Medicine, Erciyes University Medical School, Kayseri, Turkey.
authors.forename: Polat
authors.initials: P
authors.lastname: Durukan
authors.forename: Seda
authors.initials: S
authors.lastname: Ozkan
authors.forename: Ibrahim
authors.initials: I
authors.lastname: Ikizceli
authors.forename: Alper
authors.initials: A
authors.lastname: Vardar
authors.forename: Afsin
authors.initials: A
authors.lastname: Ipekci
authors.forename: Ali
authors.initials: A
authors.lastname: Duman
mesh_terms: D003287:Contrast Media / Q000009:adverse effects*; D003404:Creatinine / Q000097:blood; D004632:Emergency Medical Services; D005260:Female; D005919:Glomerular Filtration Rate; D006305:Health Status Indicators; D006801:Humans; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D009422:Nervous System Diseases / Q000139:chemically induced*; D011446:Prospective Studies; D018570:Risk Assessment / Q000379:methods; D012307:Risk Factors; D013997:Time Factors; D014057:Tomography, X-Ray Computed / Q000379:methods*; D014508:Urea / Q000097:blood
chemical_list: D003287:Contrast Media; D014508:Urea; D003404:Creatinine