title: Novel (2R,3R)-2,3-butanediol dehydrogenase from potential industrial strain Paenibacillus polymyxa ATCC 12321.
abstract: A (2R,3R)-2,3-butanediol dehydrogenase (BDH99::67) from Paenibacillus polymyxa ATCC 12321 was functionally characterized. The genetic characteristics of BDH99::67 are completely different from those of meso- and (2S,3S)-2,3-butanediol dehydrogenases. The results showed that BDH99::67 belongs to the medium-chain dehydrogenase/reductase superfamily and not to the short-chain dehydrogenase/reductase superfamily, to which meso- and (2S,3S)-2,3-butanediol dehydrogenases belong.
authors.affiliation: Institute of Bioprocess and Biosystems Engineering, Hamburg University of Technology, 21071 Hamburg, Germany.
authors.forename: Bo
authors.initials: B
authors.lastname: Yu
authors.forename: Jibin
authors.initials: J
authors.lastname: Sun
authors.forename: Rajesh Reddy
authors.initials: RR
authors.lastname: Bommareddy
authors.forename: Lifu
authors.initials: L
authors.lastname: Song
authors.forename: An-Ping
authors.initials: AP
authors.lastname: Zeng
mesh_terms: D000429:Alcohol Oxidoreductases / Q000235:genetics* / Q000378:metabolism*; D002072:Butylene Glycols / Q000378:metabolism*; D004269:DNA, Bacterial / Q000737:chemistry / Q000235:genetics; D007700:Kinetics; D008969:Molecular Sequence Data; D056507:Paenibacillus / Q000201:enzymology*; D010802:Phylogeny; D017422:Sequence Analysis, DNA; D017385:Sequence Homology
chemical_list: D002072:Butylene Glycols; D004269:DNA, Bacterial; C026978:2,3-butylene glycol; D000429:Alcohol Oxidoreductases; C019801:butanediol dehydrogenase