title: Use of 5-aminolevulinic acid for the confirmation of deep-seated brain tumors during stereotactic biopsy. Report of 2 cases.
abstract: 5-Aminolevulinic acid (ALA) has been successfully used to confirm the target tumor tissues obtained during stereotactic biopsy. The authors report their experience with 2 patients who underwent stereotactic biopsies of thalamic malignant lymphoma and pontine glioma utilizing 5-ALA. Intraoperatively, the tumor specimens fluoresced, allowing for confirmation that the obtained target specimen contained tumor tissues. No serious side effects or complications occurred.
authors.affiliation: Department of Neurosurgery, Rinku General Medical Center, Izumisano, Osaka, Japan. s-moriuchi@rgmc.izumisano.osaka.jp
authors.forename: Shusuke
authors.initials: S
authors.lastname: Moriuchi
authors.forename: Kimito
authors.initials: K
authors.lastname: Yamada
authors.forename: Makoto
authors.initials: M
authors.lastname: Dehara
authors.forename: Yoshifumi
authors.initials: Y
authors.lastname: Teramoto
authors.forename: Takao
authors.initials: T
authors.lastname: Soda
authors.forename: Masami
authors.initials: M
authors.lastname: Imakita
authors.forename: Mamoru
authors.initials: M
authors.lastname: Taneda
mesh_terms: D000368:Aged; D000622:Aminolevulinic Acid; D001254:Astrocytoma / Q000175:diagnosis* / Q000473:pathology; D001706:Biopsy / Q000379:methods; D001932:Brain Neoplasms / Q000175:diagnosis* / Q000473:pathology; D002648:Child; D005260:Female; D006801:Humans; D016403:Lymphoma, Large B-Cell, Diffuse / Q000175:diagnosis* / Q000473:pathology; D008297:Male; D011149:Pons / Q000473:pathology; D013238:Stereotaxic Techniques; D013788:Thalamus / Q000473:pathology
chemical_list: D000622:Aminolevulinic Acid