title: Screening of peptides which suppress the proliferation of transformed cells.
abstract: We have carried out three rounds of screening tests using 239 synthetic tripeptides for the growth-inhibitory activity toward tumor cells and found that those having amino acid sequences of Pro-Thr-Trp or Glu-Arg-Pro effectively inhibit proliferation of transformed cells. These peptides could be the fundamental structures of new types of anticancer drugs.
authors.affiliation: MITSUI PHARMACEUT INC,INST BIOL SCI,MOBARA,CHIBA 297,JAPAN. MITSUI PHARMACEUT INC,POSTMARKETING SURVEILLANCE DEPT,CHUO KU,TOKYO 103,JAPAN.
authors.forename: T
authors.initials: T
authors.lastname: Hiwasa
authors.forename: C
authors.initials: C
authors.lastname: Soeda
authors.forename: S
authors.initials: S
authors.lastname: Takanohashi
authors.forename: H
authors.initials: H
authors.lastname: Kobayashi
authors.forename: A
authors.initials: A
authors.lastname: Suzuki
authors.forename: T
authors.initials: T
authors.lastname: Ueyama
authors.forename: Y
authors.initials: Y
authors.lastname: Ike