title: The tale of TL1A in inflammation.
abstract: TL1A (also known as TNFSF15) is a tumor necrosis factor (TNF) family member expressed by monocytes, macrophages, dendritic cells (DCs), synovial fibroblasts, and endothelial cells in response to stimulation by cytokines, immune complexes, and microorganisms. Its cell surface receptor, DR3 (also known as TNFSF25, WSL-1, TRAMP, and LARD), is mainly expressed by T cells.
authors.affiliation: Department of Inflammation, Amgen Inc., Thousand Oaks, California, USA. hhsu@amgen.com
authors.forename: H
authors.initials: H
authors.lastname: Hsu
authors.forename: J L
authors.initials: JL
authors.lastname: Viney
mesh_terms: D000818:Animals; D004751:Enteritis / Q000276:immunology*; D005786:Gene Expression Regulation; D020397:Goblet Cells / Q000276:immunology*; D006801:Humans; D006965:Hyperplasia / Q000276:immunology*; D018793:Interleukin-13 / Q000276:immunology*; D007413:Intestinal Mucosa / Q000276:immunology* / Q000473:pathology*; D050378:T-Lymphocytes, Regulatory / Q000276:immunology*; D053380:Tumor Necrosis Factor Ligand Superfamily Member 15 / Q000276:immunology*
chemical_list: D018793:Interleukin-13; D053380:Tumor Necrosis Factor Ligand Superfamily Member 15