title: Clinical trials and treatment of the elderly diagnosed with ovarian cancer.
abstract: Elderly patients are more commonly diagnosed with advanced ovarian cancer and represent a growing proportion of all ovarian cancer cases. Despite this, the elderly have historically been underrepresented in clinical trials. Because clinical trials form the basis for most treatment guidelines and the elderly have been, to date, largely excluded from this process, little is known about the appropriate assessment and treatment of elderly ovarian cancer patients. Recognizing this knowledge deficit and the pressing need to correct it, this article aimed to summarize existing data and identify future areas of research focus.
authors.affiliation: Department of Medical Oncology, Lyon University, Hospices Civils de Lyon, Pierre-Bénite Cédex, France.
authors.forename: Gilles
authors.initials: G
authors.lastname: Freyer
authors.forename: Anna V
authors.initials: AV
authors.lastname: Tinker
mesh_terms: D017668:Age of Onset; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002277:Carcinoma / Q000175:diagnosis / Q000453:epidemiology / Q000401:mortality / Q000628:therapy*; D002986:Clinical Trials as Topic / Q000379:methods*; D005260:Female; D015577:Geriatric Assessment / Q000379:methods; D013509:Gynecologic Surgical Procedures; D006801:Humans; D010051:Ovarian Neoplasms / Q000175:diagnosis / Q000453:epidemiology / Q000401:mortality / Q000628:therapy*