title: The Movement Disorders task force review of dysautonomia rating scales in Parkinson's disease with regard to symptoms of orthostatic hypotension.
abstract: Orthostatic hypotension is defined as a blood pressure fall of > 20 mm Hg systolic and/or 10 mm Hg diastolic within 3 minutes of an upright position. The Movement Disorders Society commissioned a task force to assess existing clinical rating scales addressing symptoms of orthostatic hypotension in Parkinson's disease. Seven neurologists and a clinimetrician assessed each scale's previous use and critiqued its clinimetric properties. A scale was "recommended" if it had been applied to populations of patients with Parkinson's disease, with data on its use in studies beyond the group that developed the scale, and was found to be clinimetrically valid. A scale was considered "suggested" if it had been applied to Parkinson's disease, but only 1 of the other criteria was applied. A scale was "listed" if it met only 1 criterion. Symptoms of orthostatic hypotension are generally assessed in scales on wider autonomic or nonmotor symptoms. Some scales designed to detect orthostatic hypotension-related symptoms provide information on their severity: the AUTonomic SCale for Outcomes in PArkinson's Disease and the COMPosite Autonomic Symptom Scale met criteria for recommended with some limitations; the Novel Non-Motor Symptoms Scale and the Orthostatic Grading Scale were classified as suggested. The Self-completed Non-Motor Symptoms Questionnaire for Parkinson's Disease was classified as suggested as a tool for screening orthostatic symptoms. However, these and the listed scales need further validation and application before they can be recommended for clinical use in patients with Parkinson's disease.
authors.affiliation: Reference Centre for MSA, University Hospital, INSERM U1048 Eq8, Toulouse, France. pavy-letraon.a@chu-toulouse.fr
authors.forename: Anne
authors.initials: A
authors.lastname: Pavy-Le Traon
authors.forename: Gerard
authors.initials: G
authors.lastname: Amarenco
authors.forename: Susanne
authors.initials: S
authors.lastname: Duerr
authors.forename: Horacio
authors.initials: H
authors.lastname: Kaufmann
authors.forename: Heinz
authors.initials: H
authors.lastname: Lahrmann
authors.forename: Stephanie R
authors.initials: SR
authors.lastname: Shaftman
authors.forename: François
authors.initials: F
authors.lastname: Tison
authors.forename: Gregor K
authors.initials: GK
authors.lastname: Wenning
authors.forename: Christopher G
authors.initials: CG
authors.lastname: Goetz
authors.forename: Werner
authors.initials: W
authors.lastname: Poewe
authors.forename: Cristina
authors.initials: C
authors.lastname: Sampaio
authors.forename: Anette
authors.initials: A
authors.lastname: Schrag
authors.forename: Glenn T
authors.initials: GT
authors.lastname: Stebbins
authors.forename: Olivier
authors.initials: O
authors.lastname: Rascol
mesh_terms: D026683:Advisory Committees / Q000592:standards*; D006801:Humans; D007024:Hypotension, Orthostatic / Q000209:etiology*; D010300:Parkinson Disease / Q000150:complications* / Q000175:diagnosis*; D039781:PubMed / Q000706:statistics & numerical data; D015203:Reproducibility of Results; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires