title: [Osteocytic bone remodeling: history of the problem, morphological markers].
abstract: On the basis of the authors' own results and the analysis of the literature, the morphological markers of resorptive and synthetic phases of osteocytic bone remodeling under physiological conditions, are discussed. Their application by different authors is considered taking into account the history of the research of the osteocyte role in bone matrix metabolism (synthesis and resorption). Currently, there arose an urgent need for the quantitative assessment of osteocyte remodeling by combining routine histological methods of the osseous tissue study with the possibilities of modern image analysis systems.
authors.forename: A S
authors.initials: AS
authors.lastname: Avrunin
authors.forename: R M
authors.initials: RM
authors.lastname: Tikhilov
mesh_terms: D015415:Biomarkers / Q000032:analysis; D001857:Bone Matrix / Q000166:cytology / Q000502:physiology; D016723:Bone Remodeling / Q000502:physiology*; D002118:Calcium / Q000378:metabolism*; D006801:Humans; D010011:Osteocytes / Q000166:cytology* / Q000502:physiology*
chemical_list: D015415:Biomarkers; D002118:Calcium