title: The biomechanical properties of the cornea in patients with systemic lupus erythematosus.
abstract: PUPOSE: The purpose of this study was to compare the biomechanical properties of the cornea and intraocular pressure (IOP) between patients with systemic lupus erythematosis (SLE) and age-matched controls.
  
  
  METHODS
  In this prospective study, 30 healthy individuals (control group) and 30 patients with SLE (study group) underwent Reichert ocular response analyzer (ORA) measurements. In the right eye of each participant, the corneal hysteresis (CH), corneal resistance factor (CRF), and Goldman-related IOP (IOPg) were recorded using the ORA.
  
  
  RESULTS
  Mean CH, CRF, IOPg were significantly different between groups. Mean CH was 10.2 ± 0.6 mm Hg in the study group and 11.3 ± 1.3 in the control group (P=0.02); mean CRF was 9.7 ± 1.1 mm Hg and 11.9 ± 1.5 mm Hg, respectively (P=0.001). Mean IOP(g) was 13.9 ± 2.9 mm Hg in the study group and 16.9 ± 2.6 mm Hg in the control group (P=0.001).
  
  
  CONCLUSIONS
  The biomechanical properties of the cornea are altered in patients with SLE compared with normal controls. These findings should be taken into account when measuring IOP values in patients with SLE as IOP readings may be underestimated in SLE eyes.
authors.affiliation: Beyoglu Eye Research and Training Hospital, Istanbul, Turkey.
authors.forename: A T
authors.initials: AT
authors.lastname: Yazici
authors.forename: N
authors.initials: N
authors.lastname: Kara
authors.forename: K
authors.initials: K
authors.lastname: Yüksel
authors.forename: H
authors.initials: H
authors.lastname: Altinkaynak
authors.forename: O
authors.initials: O
authors.lastname: Baz
authors.forename: E
authors.initials: E
authors.lastname: Bozkurt
authors.forename: A
authors.initials: A
authors.lastname: Demirok
mesh_terms: D000328:Adult; D001696:Biomechanical Phenomena; D016022:Case-Control Studies; D003315:Cornea / Q000502:physiology*; D004548:Elasticity; D005260:Female; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology*; D008180:Lupus Erythematosus, Systemic / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D014065:Tonometry, Ocular