title: Skin lesion by methicillin-resistant Staphylococcus aureus ST398-t1451 in a Spanish pig farmer: possible transmission from animals to humans.
abstract: Skin lesions by methicillin-resistant Staphylococcus aureus (MRSA) of the lineage ST398-t1451 were detected in a pig-farmer in Spain in 2010. Similar MRSA ST398-t1451 strains were also detected in nasal samples from the patient, his brother, and nine pigs from his farm. All human and animal strains were ascribed to the SCCmec type V and the agr type I, showed tetracycline-erythromycin-clindamycin resistances, and harbored the tetK, tetM, and ermC resistance genes. They were negative for all tested toxin genes (lukS/lukF, tst, eta, etb, and etd). All human and animal strains showed closely related pulsed-field gel electrophoresis-ApaI patterns. Possible MRSA transmission from animals to humans is suggested.
authors.affiliation: Área Bioquímica y Biología Molecular, Universidad de La Rioja, Logroño, Spain.
authors.forename: Carmen
authors.initials: C
authors.lastname: Lozano
authors.forename: Carmen
authors.initials: C
authors.lastname: Aspiroz
authors.forename: Luis
authors.initials: L
authors.lastname: Charlez
authors.forename: Elena
authors.initials: E
authors.lastname: Gómez-Sanz
authors.forename: Miguel
authors.initials: M
authors.lastname: Toledo
authors.forename: Myriam
authors.initials: M
authors.lastname: Zarazaga
authors.forename: Carmen
authors.initials: C
authors.lastname: Torres
mesh_terms: D000328:Adult; D000818:Animals; D006801:Humans; D008297:Male; D055624:Methicillin-Resistant Staphylococcus aureus / Q000145:classification* / Q000302:isolation & purification; D013030:Spain / Q000453:epidemiology; D013207:Staphylococcal Skin Infections / Q000453:epidemiology / Q000382:microbiology*; D013552:Swine; D013553:Swine Diseases / Q000453:epidemiology / Q000382:microbiology*; D015047:Zoonoses / Q000382:microbiology*