title: Gas chromatographic enantioseparation of derivatized α-amino acids on chiral stationary phases--past and present.
abstract: The historical development of the enantioseparation of derivatized α-amino acids by high-resolution capillary gas chromatography on chiral stationary phases derived from α-amino acid-derivatives and modified cyclodextrins is described. The pioneering work emerging from Emanuel Gil-Av and his associates at the Weizmann Institute of Science is reviewed. A bridge to more recent developments is spanned aimed at helping to select appropriate tools for contemporary chiral α-amino acid analysis by gas chromatography in different research areas.
authors.affiliation: Institute of Organic Chemistry, University of Tübingen, Auf der Morgenstelle 18, D-72076 Tübingen, Germany. volker.schurig@uni-tuebingen.de
authors.forename: Volker
authors.initials: V
authors.lastname: Schurig
mesh_terms: D000596:Amino Acids / Q000032:analysis* / Q000737:chemistry; D002849:Chromatography, Gas / Q000379:methods* / Q000639:trends; D003505:Cyclodextrins; D006801:Humans; D009930:Organic Chemicals; D012833:Siloxanes; D013237:Stereoisomerism
chemical_list: D000596:Amino Acids; C041118:Chirasil-Val; D003505:Cyclodextrins; D009930:Organic Chemicals; D012833:Siloxanes; C090733:Chirasil-Dex