title: From endocrine disruptors to nanomaterials: advancing our understanding of environmental health to protect public health.
abstract: Environmental health science is the study of the impact of the environment on human health. This paper introduces basic topics in environmental health, including clean air, clean water, and healthful food, as well as a range of current issues and controversies in environmental health. Conceptual shifts in modern toxicology have changed the field. There is a new understanding of the effects of exposure to chemicals at low doses, and in combination, and the impact on human growth and development. Other emerging topics include the role of epigenetics, or changes in genes and gene expression that can be brought about by chemical exposure; environmental justice; and potential effects of engineered nanomaterials and climate change. We review the important implications for public health policy and recommend a broad environmental health research strategy aimed at protecting and improving human health.
authors.affiliation: National Institute of Environmental Health Sciences and National Toxicology Program in Research Triangle Park, North Carolina, USA. birnbaumls@niehs.nih.gov
authors.forename: Linda S
authors.initials: LS
authors.lastname: Birnbaum
authors.forename: Paul
authors.initials: P
authors.lastname: Jung
mesh_terms: D057231:Climate Change; D003247:Conservation of Natural Resources / Q000639:trends; D004305:Dose-Response Relationship, Drug; D052244:Endocrine Disruptors / Q000633:toxicity*; D004782:Environmental Health / Q000639:trends*; D044127:Epigenesis, Genetic / Q000187:drug effects; D057890:Epigenomics / Q000639:trends; D005544:Forecasting; D015870:Gene Expression / Q000187:drug effects; D006801:Humans; D049329:Nanostructures / Q000633:toxicity*; D011634:Public Health / Q000639:trends*; D014481:United States
chemical_list: D052244:Endocrine Disruptors