title: Quality of life assessment in patients with cystic fibrosis by means of the Cystic Fibrosis Questionnaire.
abstract: OBJECTIVE
  To assess the quality of life (QoL) of patients with cystic fibrosis (CF) followed at a university referral center for CF.
  
  
  METHODS
  A cross-sectional study involving application of the Cystic Fibrosis Questionnaire (CFQ) and Shwachman score in CF patients between April of 2008 and June of 2009.
  
  
  RESULTS
  The sample consisted of 75 patients. The mean age was 12.5 ± 5.1 years (range, 6.1-26.4 years). The patients were divided into three groups by age in years: group I (< 12), II (12-14), and III (> 14). The highest and lowest CFQ scores were for the nutrition domain in group III (89.3 ± 16.2) and the social domain in group II (59.5 ± 22.3), respectively. Groups I and III differed significantly regarding the treatment domain (p = 0.001). Regarding Shwachman scores, there were significant differences between patients scoring < 70 and those scoring > 70 in the social (group I; p = 0.045), respiratory (group II; p = 0.053), and digestive (p = 0.042) domains. In group III, severity did not correlate with QoL. In groups I and II, patients with an FEV1 < 80% of predicted did not differ from other patients for any CFQ domain. However, in group III, values for the following domains were significantly lower in patients with an FEV1 < 80%: physical (p = 0.012); body image (p = 0.031); respiratory (p = 0.023), emotional (p = 0.041); and social role (p = 0.024).
  
  
  CONCLUSIONS
  It is important to assess QoL in CF patients, because it can improve treatment compliance.
authors.affiliation: Hospital de Clínicas, Universidade Estadual de Campinas, Campinas, SP, Brasil.
authors.forename: Milena Antonelli
authors.initials: MA
authors.lastname: Cohen
authors.forename: Maria Ângela Gonçalves de Oliveira
authors.initials: MÂ
authors.lastname: Ribeiro
authors.forename: Antonio Fernando
authors.initials: AF
authors.lastname: Ribeiro
authors.forename: José Dirceu
authors.initials: JD
authors.lastname: Ribeiro
authors.forename: André Moreno
authors.initials: AM
authors.lastname: Morcillo
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D003430:Cross-Sectional Studies; D003550:Cystic Fibrosis / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008297:Male; D011788:Quality of Life; D012720:Severity of Illness Index; D018709:Statistics, Nonparametric; D011795:Surveys and Questionnaires; D055815:Young Adult