title: Nucleophilic deoxyfluorination of catechols.
abstract: Nucleophilic deoxyfluorinaiton of one of the two hydroxyl groups of catechols has been developed via the Umpolung concept. This method was successively applied to naturally occurring catechols, such as catechins and dopamine, to produce novel fluorinated analogues.
authors.affiliation: School of Pharmaceutical Sciences, University of Shizuoka, Suruga-ku, Shizuoka, Japan.
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Nemoto
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Nishiyama
authors.forename: Shuji
authors.initials: S
authors.lastname: Akai
mesh_terms: D002384:Catalysis; D002392:Catechin / Q000737:chemistry; D002396:Catechols / Q000737:chemistry*; D004298:Dopamine / Q000737:chemistry; D006845:Hydrocarbons, Fluorinated / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure
chemical_list: D002396:Catechols; D006845:Hydrocarbons, Fluorinated; D002392:Catechin; D004298:Dopamine