title: In frame deletion of intron-7 in the p53 gene in a human tonsil tumor.
abstract: We here report a unique intron deletion in the p53 gene. Analysis of a human tonsil tumor that expressed elevated levels of p53 showed a deletion of the entire intron 7 in one of the p53 alleles, leaving the coding sequence intact. The significance of the intron 7 deletion for the development of the tonsil tumor is discussed.
authors.affiliation: HUDDINGE HOSP,KAROLINSKA INST,DEPT IMMUNOL,S-14186 HUDDINGE,SWEDEN. HUDDINGE HOSP,KAROLINSKA INST,DEPT MICROBIOL,S-14186 HUDDINGE,SWEDEN. KAROLINSKA HOSP,DEPT OTORHINOLARYNGOL,S-10401 STOCKHOLM,SWEDEN. HUDDINGE HOSP,KAROLINSKA INST,DEPT PATHOL,S-14186 HUDDINGE,SWEDEN. HUDDINGE HOSP,KAROLINSKA INST,DEPT INFECT DIS,S-14186 HUDDINGE,SWEDEN.
authors.forename: K
authors.initials: K
authors.lastname: Magnusson
authors.forename: Z
authors.initials: Z
authors.lastname: Berke
authors.forename: E
authors.initials: E
authors.lastname: Munckwikland
authors.forename: I
authors.initials: I
authors.lastname: Lewensohnfuchs
authors.forename: G
authors.initials: G
authors.lastname: Klein
authors.forename: T
authors.initials: T
authors.lastname: Dallianis
authors.forename: K
authors.initials: K
authors.lastname: Wiman