title: Long-term survival in high-grade soft-tissue sarcoma - prognostic factors in synovial sarcoma.
abstract: One hundred and thirteen consecutive patients with synovial sarcoma of the extremity or trunk were studied retrospectively. Seventy-six patients had surgery of their primary tumor at our institution (37 elsewhere). Mean follow-up for survivors was 124 (13-302) months. Thirteen developed local recurrence and 62 pulmonary metastases. Increasing surgical margin, adjuvant radiotherapy, and center-based treatment correlated with better local control. Older age, large tumor size and proximal position on the limb correlated with more metastases. Overall 5- and 10-year survival was 68 and 56%, respectively. Age, size, metastasis, metastasis free period and center-based treatment were independently prognostic.
authors.affiliation: MAYO CLIN & MAYO FDN,DEPT ORTHOPED,ROCHESTER,MN 55905. MAYO CLIN & MAYO FDN,DEPT PATHOL,ROCHESTER,MN 55905.
authors.forename: P
authors.initials: P
authors.lastname: Choong
authors.forename: D
authors.initials: D
authors.lastname: Pritchard
authors.forename: F
authors.initials: F
authors.lastname: Sim
authors.forename: M
authors.initials: M
authors.lastname: Rock
authors.forename: A
authors.initials: A
authors.lastname: Nascimento