title: Controlled electrochemically-assisted deposition of sol-gel biocomposite on electrospun platinum nanofibers.
abstract: The modification of platinum nanofibers by silica using the electrochemically-assisted deposition is reported here. Pt nanofibers are obtained by electrospinning and deposited on a glass substrate. The electrochemically-assisted deposition of the sol-gel material then gives the unique possibility to finely tune the silica film thickness around these nanofibers. It also allows the successful encapsulation of a biomolecule (glucose oxidase was chosen here as a model) while retaining its biological activity, as pointed out via the electrochemical monitoring of H(2)O(2) produced upon addition of glucose in the medium. This silica-glucose oxidase composite offers the possibility of comparing systematically the influence of the deposition time on the bioelectrode response and to compare it with the particular features of the deposits. It was found that the film first grew uniformly around the nanofibers and then started to deposit between them, covering the whole sample (fibers and glass substrate), and tended to fully embed the nanofibers for prolonged deposition. The thickness of the silica film is critical for the electroactivity of the biocomposite, the best response being obtained for a silica layer thickness in the range of the fiber diameter (∼50 nm).
authors.affiliation: Laboratoire de Chimie Physique et Microbiologie pour l'Environnement, UMR 7564, CNRS-Institut Jean Barriol-Nancy-Université, 405 rue de Vandœuvre, 54600 Villers-lès-Nancy, France.
authors.forename: Ievgen
authors.initials: I
authors.lastname: Mazurenko
authors.forename: Mathieu
authors.initials: M
authors.lastname: Etienne
authors.forename: Rainer
authors.initials: R
authors.lastname: Ostermann
authors.forename: Bernd M
authors.initials: BM
authors.lastname: Smarsly
authors.forename: Oksana
authors.initials: O
authors.lastname: Tananaiko
authors.forename: Vladimir
authors.initials: V
authors.lastname: Zaitsev
authors.forename: Alain
authors.initials: A
authors.lastname: Walcarius
mesh_terms: D001234:Aspergillus niger / Q000201:enzymology; D004563:Electrochemistry; D004800:Enzymes, Immobilized / Q000737:chemistry / Q000378:metabolism; D005949:Glucose Oxidase / Q000737:chemistry / Q000378:metabolism; D057139:Nanofibers / Q000737:chemistry*; D036103:Nanotechnology / Q000379:methods*; D010984:Platinum / Q000737:chemistry*; D012822:Silicon Dioxide / Q000737:chemistry
chemical_list: D004800:Enzymes, Immobilized; D010984:Platinum; D012822:Silicon Dioxide; D005949:Glucose Oxidase