title: The antibody titers to Helicobacter pylori in 7 - 12 year old iron deficiency anemic children, in Ilam.
abstract: BACKGROUND
  It has recently been revealed that H. pylori infection is one the most important causes of anemia inhibiting iron uptake. The current study was designed to evaluate the correlation between the iron deficiency anemia and IgG to H. pylori in anemic children.
  
  
  METHODS
  In this analytical study, 100 anemic children were analyzed using total Iron, Ferritin, TIBC and H. pylori IgG assay. Data were collected using a questionnaire including parameters of age, blood group, infancy nutrition, iron consumption, fatigue, weakness, height, weight, gastrointestinal infectious, parasitic and blood diseases, parent literacy, income, inhabitation, etc. Data were analyzed using Multivariate Regression Analysis Models, Pearson Correlation- test and Kolmogrov Smirnov.
  
  
  RESULTS
  The most prevalent blood group detected in the study sample was group O (62%); 79% were breastfed, 9% were bottle- fed, 12% were both breastfed and bottle- fed. The history of gastrointestinal disorders was mentioned amongst 91% of the patients' family members. A significant relationship was observed between the iron level with serum, ferritin, level of TIBC and elevated level of IgG titer to H. pylori (p < 0.001). There was a significant association between the shared dishes, GI disorders, fatigue and weakness and level of TIBC, ferritin, Iron and IgG (p < 0.001).
  
  
  CONCLUSIONS
  The significant relationship between the iron level, IgG titer and H. pylori infection rate can be referred to as important factors influencing the anemia rate. Therefore, H. pylori IgG test can be checked for anemia together with the other routine tests.
authors.affiliation: Immunology, Ilam University of Medical Sciences, Ilam, Iran.
authors.forename: Morteza
authors.initials: M
authors.lastname: Hoseinzadeh
authors.forename: Afra
authors.initials: A
authors.lastname: Khosravi
authors.forename: Koroush
authors.initials: K
authors.lastname: Sayemiri
authors.forename: Mohammad Hossein
authors.initials: MH
authors.lastname: Rasoli
authors.forename: Alireza
authors.initials: A
authors.lastname: Mohaveri