title: Identification of differentially expressed genes in breast cancer.
abstract: A number of genes differentially expressed in breast cancer were isolated using a subtractive cloning technique. DNA sequence analysis and GenBank searches of T4F10, T2H7, and T2E5 cDNA clones found them to be identical with E2A, MSS1, and SEC13R genes. Their expression in a variety of primary breast tumor and cancer cell lines was compared with c-ERB-B2 and pS2 by Northern blot analysis. In breast cancer cell lines, the genes that we isolated are more frequently expressed than the previously described c-ERB-B2 and pS2.
authors.affiliation: UNIV TORONTO,DEPT PATHOL,FAC MED,TORONTO,ON,CANADA. UNIV TORONTO,FAC DENT,TORONTO,ON,CANADA. UNIV TORONTO,WOMENS COLL HOSP,TORONTO,ON,CANADA. UNIV BRADFORD,CLIN ONCOL UNIT,BRADFORD BD7 1DP,W YORKSHIRE,ENGLAND. MEM SLOAN KETTERING CANC CTR,NEW YORK,NY. NCI,MOLEC ONCOL LAB,FREDERICK,MD.
authors.forename: A
authors.initials: A
authors.lastname: Burger
authors.forename: H
authors.initials: H
authors.lastname: Li
authors.forename: A
authors.initials: A
authors.lastname: Panayiotakis
authors.forename: A
authors.initials: A
authors.lastname: Salesiotis
authors.forename: A
authors.initials: A
authors.lastname: Seth