title: A rare head-head binding pattern in bisbenzylisoquinoline alkaloids.
abstract: Bioassay-guided fractionation of Berberis tabiensis against Culex quinquefasciatus third instar larvae afforded a new bisbenzyltetrahydroisoquinoline alkaloid having an unusual head-head binding pattern. This new alkaloid (tabienine B) is the first member of this family found to possess a diphenyl ether bridge in C-6 and C-7'.
authors.affiliation: Departamento de Quimica, Facultad de Ciencias, Universidad Nacional de Colombia, Carrera 30 No 45-03, Bogota, Colombia. arquevedop@unal.edu.co
authors.forename: Rodolfo
authors.initials: R
authors.lastname: Quevedo
authors.forename: Lorena
authors.initials: L
authors.lastname: Nunez
authors.forename: Barbara
authors.initials: B
authors.lastname: Moreno
mesh_terms: D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D000818:Animals; D044182:Benzylisoquinolines / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D028142:Berberis / Q000737:chemistry*; D003105:Colombia; D003465:Culex / Q000187:drug effects*; D007306:Insecticides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D007814:Larva; D015394:Molecular Structure; D013329:Structure-Activity Relationship
chemical_list: D000470:Alkaloids; D044182:Benzylisoquinolines; D007306:Insecticides; C559763:tabienine B