title: Angiolipoma in sellar, suprasellar and parasellar region: report on two new cases and review of literature.
abstract: Angiolipomas of CNS are very rare; more than 90% involve the spinal canal. There are only a few case reports documenting the tumor in the sellar/suprasellar region. We report 2 cases of angiolipoma involving sellar/suprasellar and right parasellar region in two female patients. On histopathology the lesion was composed of vascular component which was of cavernous type in one patient and of capillary caliber in the other with admixture of mature adipocytes. The MRI findings were distinctive as the lesion was predominantly iso-to-hypointense on T1W sequence, hyperintense on T2WI and FLAIR sequence. In addition, a few small hyperintense areas were noted on plain T1W images which may represent intralesional fat. One of the cases also showed lipid lactate peak on MR spectroscopy. To the best of our knowledge only 8 other cases of sellar, parasellar angiolipomas have been reported in indexed literature. MRI with fat suppression sequences should be routinely performed in lesions in such locations with hyperintense areas on T1WI as the incidence of intraoperative blood loss is very high. A preoperative suspicion of the diagnosis might help in reducing the patient morbidity.
authors.affiliation: Department of Pathology and Transfusion Medicine, SSSIHMS, Bangalore, India. nandita.g@rediffmail.com
authors.forename: N
authors.initials: N
authors.lastname: Ghosal
authors.forename: S V
authors.initials: SV
authors.lastname: Furtado
authors.forename: N A
authors.initials: NA
authors.lastname: Saikiran
authors.forename: K
authors.initials: K
authors.lastname: Gupta
authors.forename: A S
authors.initials: AS
authors.lastname: Hegde
mesh_terms: D018206:Angiolipoma / Q000473:pathology*; D003937:Diagnosis, Differential; D005260:Female; D006391:Hemangioma / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D010911:Pituitary Neoplasms / Q000473:pathology*