title: Cardiac biomarker response to intermittent exercise bouts.
abstract: The impact of intermittent exercise on cardiac biomarker release has not been clearly established. In experienced athletes, we examined the acute effect of a heavy resistance training session (n=18 males) and an indoor soccer match (n=21, 11 males, 10 females) on the release of cTnI, cTnT, and NT-proBNP. Biomarkers were assayed from blood samples collected at rest, immediately post- and at 1, 3, 6, 12, and 24 h post-exercise. The heavy resistance training session resulted in an increase in NT-proBNP (pre: 15 ± 17, peak post: 41 ± 56 ng L (-1); p=0.001) but not in cTnI (pre: 0.024 ± 0.009, peak post: 0.025 ± 0.011 μg L (-1), p=0.809) or cTnT (undetectable in all samples). The indoor soccer match led to an increase in the release of NT-proBNP (pre: 28 ± 32, peak post: 66 ± 56 ng L (-1); p=0.000) and cTnI (pre: 0.026 ± 0.047, peak post: 0.033 ± 0.051 μg L (-1); p=0.008) in both males and females but not cTnT (detectable in only one subject). The current data suggest that intermittent bouts of exercise result in only modest perturbations of cardiac biomarkers with very limited evidence of myocyte injury/insult.
authors.affiliation: University of Zaragoza, Section of Physical Education and Sports, Spain. kique_79@hotmail.com
authors.forename: L E
authors.initials: LE
authors.lastname: Carranza-García
authors.forename: K
authors.initials: K
authors.lastname: George
authors.forename: E
authors.initials: E
authors.lastname: Serrano-Ostáriz
authors.forename: R
authors.initials: R
authors.lastname: Casado-Arroyo
authors.forename: A L
authors.initials: AL
authors.lastname: Caballero-Navarro
authors.forename: A
authors.initials: A
authors.lastname: Legaz-Arrese
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000097:blood; D005260:Female; D006321:Heart / Q000502:physiology*; D006801:Humans; D008297:Male; D032383:Myocytes, Cardiac / Q000502:physiology; D020097:Natriuretic Peptide, Brain / Q000097:blood / Q000378:metabolism*; D010446:Peptide Fragments / Q000097:blood / Q000378:metabolism*; D012916:Soccer / Q000502:physiology*; D019210:Troponin I / Q000097:blood / Q000378:metabolism*; D020107:Troponin T / Q000097:blood / Q000378:metabolism*; D014891:Weight Lifting / Q000502:physiology*; D055815:Young Adult
chemical_list: D015415:Biomarkers; D010446:Peptide Fragments; D019210:Troponin I; D020107:Troponin T; C109794:pro-brain natriuretic peptide (1-76); D020097:Natriuretic Peptide, Brain