title: [The secondary metabolites of the HS-3 Alternaria sp. fungus associated with holothurians].
abstract: OBJECTIVE
  The metabolites of HS-3 associated with holothurians were studied, which was identified by molecular biology as Alternaria sp..
  
  
  METHODS
  The holothurians were gathered from the Sea of Zhifu Islet, Shandong Province. HS-3 Alternaria sp. was culternitived in potato medium, and four compound was got by TLC, chromatography and HPLC, and 1-hydroxyl-3-methylanthracene-9,10-dione (1), chrysophanol (2), sterigmatocystin (3) and cerebroside (4) were elucated by modern spectrum.
  
  
  CONCLUSIONS
  All of this provides scientific data for further study of holothurians, and the four coumpouns are isolated from the microbe associated with holothurians for the first time.
authors.affiliation: Biology Institute of Shandong Academy of Science, Jinan 250014, China. liuchh@keylab.net
authors.forename: Chang-Heng
authors.initials: CH
authors.lastname: Liu
authors.forename: Xue-Kui
authors.initials: XK
authors.lastname: Xia
authors.forename: Jun
authors.initials: J
authors.lastname: Qi
authors.forename: Yong-Gang
authors.initials: YG
authors.lastname: Zhang
authors.forename: Wen-Peng
authors.initials: WP
authors.lastname: Yuan
authors.forename: Xiu-Mei
authors.initials: XM
authors.lastname: Meng
authors.forename: Ai-Rong
authors.initials: AR
authors.lastname: Jia
authors.forename: Yong-Jun
authors.initials: YJ
authors.lastname: Sun
authors.forename: Wei
authors.initials: W
authors.lastname: Hu
mesh_terms: D000528:Alternaria / Q000737:chemistry* / Q000378:metabolism; D000818:Animals; D000880:Anthraquinones / Q000737:chemistry / Q000302:isolation & purification*; D002554:Cerebrosides / Q000737:chemistry / Q000302:isolation & purification; D005285:Fermentation; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D012616:Sea Cucumbers / Q000382:microbiology*; D013241:Sterigmatocystin / Q000737:chemistry / Q000302:isolation & purification*
chemical_list: D000880:Anthraquinones; D002554:Cerebrosides; D013241:Sterigmatocystin; C027113:chrysophanic acid