title: Peptide signaling in plant development.
abstract: Cell-to-cell communication is integral to the evolution of multicellularity. In plant development, peptide signals relay information coordinating cell proliferation and differentiation. These peptides are often encoded by gene families and bind to corresponding families of receptors. The precise spatiotemporal expression of signals and their cognate receptors underlies developmental patterning, and expressional and biochemical changes over evolutionary time have likely contributed to the refinement and complexity of developmental programs. Here, we discuss two major plant peptide families which have central roles in plant development: the CLAVATA3/ENDOSPERM SURROUNDING REGION (CLE) peptide family and the EPIDERMAL PATTERNING FACTOR (EPF) family. We discuss how specialization has enabled the CLE peptides to modulate stem cell differentiation in various tissue types, and how differing activities of EPF peptides precisely regulate the stomatal developmental program, and we examine the contributions of these peptide families to plant development from an evolutionary perspective.
authors.affiliation: BIOSS Centre for Biological Signalling Studies, Faculty of Biology, University of Freiburg, 79104 Freiburg, Germany.
authors.forename: Leron
authors.initials: L
authors.lastname: Katsir
authors.forename: Kelli A
authors.initials: KA
authors.lastname: Davies
authors.forename: Dominique C
authors.initials: DC
authors.lastname: Bergmann
authors.forename: Thomas
authors.initials: T
authors.lastname: Laux
mesh_terms: D029681:Arabidopsis Proteins / Q000235:genetics / Q000502:physiology*; D005075:Biological Evolution; D002450:Cell Communication / Q000502:physiology*; D002454:Cell Differentiation / Q000502:physiology; D004268:DNA-Binding Proteins / Q000235:genetics / Q000502:physiology*; D018519:Meristem / Q000502:physiology; D008954:Models, Biological; D005810:Multigene Family / Q000235:genetics / Q000502:physiology*; D063245:Plant Development; D018517:Plant Roots / Q000502:physiology; D054046:Plant Stomata / Q000254:growth & development; D021382:Protein Sorting Signals / Q000235:genetics / Q000502:physiology*; D015398:Signal Transduction / Q000502:physiology*; D014157:Transcription Factors / Q000235:genetics / Q000502:physiology*
chemical_list: C118167:AT2G27250 protein, Arabidopsis; D029681:Arabidopsis Proteins; D004268:DNA-Binding Proteins; C547253:EPF1 protein, Arabidopsis; D021382:Protein Sorting Signals; D014157:Transcription Factors