title: Challenges and algorithm-guided treatment in major depressive disorder.
abstract: Major depressive disorder is complicated and difficult to treat, primarily because of its chronic and recurrent nature and the poor efficacy of most pharmacologic treatment options. Until more effective treatments become available, clinicians must focus on optimizing patient outcomes through patient care. Implementing measurement-based care and using treatment algorithms can reduce symptoms of depression and help patients achieve and maintain remission.
authors.affiliation: Department of Psychiatry, Vanderbilt School of Medicine, Nashville, Tennessee, USA.
authors.forename: Richard C
authors.initials: RC
authors.lastname: Shelton
authors.forename: Madhukar H
authors.initials: MH
authors.lastname: Trivedi
mesh_terms: D000465:Algorithms; D000928:Antidepressive Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D003865:Major Depressive Disorder / Q000188:drug therapy*; D004360:Drug Therapy, Computer-Assisted; D006801:Humans; D012074:Remission Induction / Q000379:methods
chemical_list: D000928:Antidepressive Agents