title: Cytological diagnostic clues in fine needle aspiration of breast myofibroblastoma: a case report.
abstract: Myofibroblastoma of the breast is a rare, benign mesenchymal tumor derived from the stroma and tends to occur mainly in middle-aged to elderly men. There are a few cases reported in the literature describing its cytological features. We report the cytological and histological findings of a breast myofibroblastoma in a 68-year-old man. He presented with a palpable nodule of 2-months duration in his left breast. The cytological smears obtained by fine needle aspiration showed less cohesive cellularity in a fascicular arrangement consisting of spindle cells with elongated cytoplasm, occasional nuclear grooves, and intranuclear cytoplasmic inclusions associated to fragments of stromal collagen. The cytological diagnosis was a mesenchymal proliferation suggesting the possibility of myofibroblastoma which was confirmed on histopathological examination. The breast myofibroblastoma has distinctive cytological features that in conjunction with the clinical and radiological data allow a specific diagnosis.
authors.affiliation: Servei d'Anatomia Patològica, Hospital Universitari Joan XXIII, Tarragona, Spain. jlandeyro@gmail.com
authors.forename: Julieta
authors.initials: J
authors.lastname: Landeyro
authors.forename: M Luisa
authors.initials: ML
authors.lastname: Díaz
authors.forename: Antoni
authors.initials: A
authors.lastname: Raventós
authors.forename: Jordi
authors.initials: J
authors.lastname: Vadillo
authors.forename: M Salomé
authors.initials: MS
authors.lastname: Martínez
mesh_terms: D000368:Aged; D044963:Biopsy, Fine-Needle; D018567:Breast Neoplasms, Male / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology*; D006651:Histocytochemistry; D006801:Humans; D008297:Male; D009379:Neoplasms, Muscle Tissue / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology*; D014463:Ultrasonography