title: Rate enhanced olefin cross-metathesis reactions: the copper iodide effect.
abstract: Copper iodide has been shown to be an effective cocatalyst for the olefin cross-metathesis reaction. In particular, it has both a catalyst stabilizing effect due to iodide ion, as well as copper(I)-based phosphine-scavenging properties that apply to use of the Grubbs-2 catalyst. A variety of Michael acceptors and olefinic partners can be cross-coupled under mild conditions in refluxing diethyl ether that avoid chlorinated solvents. This effect has also been applied to chemistry in water at room temperature using the new surfactant TPGS-750-M.
authors.affiliation: Department of Chemistry & Biochemistry, University of California, Santa Barbara, California 93106, United States.
authors.forename: Karl
authors.initials: K
authors.lastname: Voigtritter
authors.forename: Subir
authors.initials: S
authors.lastname: Ghorai
authors.forename: Bruce H
authors.initials: BH
authors.lastname: Lipshutz
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D007454:Iodides / Q000737:chemistry*; D007700:Kinetics
chemical_list: D000475:Alkenes; D007454:Iodides; D003300:Copper; C073870:cuprous iodide