title: Use of Ga-68 DOTATATE PET/CT to confirm portal vein tumor thrombosis in a patient with pancreatic neuroendocrine tumor.
abstract: A 37-year-old man complained of increasing severity and frequency of abdominal pain over a 2-year period. Initial contrast-enhanced computed tomography of the abdomen demonstrated diffuse enlargement of the pancreas associated with a filling defect in the portal vein, splenomegaly with wedge-shaped peripheral splenic hypodensities and multiple hepatic hypodensities. Findings were suggestive of a pancreatic malignancy complicated by hepatic metastases, splenic infarcts, and portal vein thrombosis. We describe the use of gallium-68 DOTA-DPhe1, Tyr3-octreotate positron emission tomography/computed tomography (Ga-68 DOTATATE PET/CT) in confirming the diagnosis of a pancreatic neuroendocrine tumor with portal vein tumor thrombosis.
authors.affiliation: Department of Nuclear Medicine and PET, Singapore General Hospital, Singapore, Singapore. tzechwan@gmail.com
authors.forename: Tze Chwan
authors.initials: TC
authors.lastname: Lim
authors.forename: Eik Hock
authors.initials: EH
authors.lastname: Tan
authors.forename: Sumbul
authors.initials: S
authors.lastname: Zaheer
mesh_terms: D000328:Adult; D006801:Humans; D008297:Male; D018358:Neuroendocrine Tumors / Q000150:complications*; D009942:Organometallic Compounds; D010190:Pancreatic Neoplasms / Q000150:complications*; D011169:Portal Vein; D049268:Positron-Emission Tomography; D014057:Tomography, X-Ray Computed; D020246:Venous Thrombosis / Q000150:complications* / Q000175:diagnosis* / Q000473:pathology / Q000503:physiopathology
chemical_list: D009942:Organometallic Compounds; C513399:gallium Ga 68 dotatate