title: New antimycobacterial triterpenoids from Rhus taitensis.
abstract: Two new triterpenoids were isolated from the leaves and twigs of Rhus taitensis. Their structures were elucidated by 1D and 2D NMR spectroscopic studies as 1,10,24,25,30-pentahydroxysqualene and dammar-20(22),24-diene-3 β,26,27-triol. Both compounds exhibited moderate antimycobacterial activities with an MIC of 45 µg/mL.
authors.affiliation: Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, Utah, USA.
authors.forename: Raquel C
authors.initials: RC
authors.lastname: Jadulco
authors.forename: Michael
authors.initials: M
authors.lastname: Koch
authors.forename: Ryan M
authors.initials: RM
authors.lastname: Van Wagoner
authors.forename: Christopher
authors.initials: C
authors.lastname: Pond
authors.forename: Osia G
authors.initials: OG
authors.lastname: Gideon
authors.forename: Teatulohi
authors.initials: T
authors.lastname: Matainaho
authors.forename: Pius
authors.initials: P
authors.lastname: Piskaut
authors.forename: Louis R
authors.initials: LR
authors.lastname: Barrows
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D002470:Cell Survival; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D009169:Mycobacterium tuberculosis / Q000187:drug effects / Q000254:growth & development; D010936:Plant Extracts / Q000737:chemistry*; D018515:Plant Leaves / Q000737:chemistry; D010946:Plants, Medicinal; D029045:Rhus / Q000737:chemistry*; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*
chemical_list: C579608:1,10,24,25,30-pentahydroxysqualene; D000900:Anti-Bacterial Agents; D010936:Plant Extracts; D014315:Triterpenes; C579607:dammar-20(22),24-diene-3beta,26,27-triol