title: Reconstructing very short TE phase rotation spectral data collected with multichannel phased-array coils at 3 T.
abstract: Phased-array volume coils were used in conjunction with the phase rotation STEAM (PR-STEAM) spectroscopy technique to acquire very short TE data from the anterior cingulate gyrus at 3 T. A method for combining PR-STEAM data from multiple subcoils is presented. The data were acquired from seven healthy participants using PR-STEAM (repetition time/mixing time/echo time=3500/10/6.5 ms, 6 cm(3), NEX=128, spectral width=2000 Hz, 2048 complex points, Δφ(1)=135°, Δφ(2)=22.5°, Δφ(3)=112.5° and Δφ(ADC)=0°). In addition to the primary metabolites, LCModel fit results suggest that glutathione and glutamate can also be identified with Cramér-Rao lower bounds of 10% or less.
authors.affiliation: Department of Radiology, Children's Healthcare of Atlanta, Atlanta, GA 30322, USA.
authors.forename: S Andrea
authors.initials: SA
authors.lastname: Wijtenburg
authors.forename: Jack
authors.initials: J
authors.lastname: Knight-Scott
mesh_terms: D000328:Adult; D001921:Brain / Q000473:pathology; D001931:Brain Mapping / Q000379:methods; D005260:Female; D005583:Fourier Analysis; D018698:Glutamic Acid / Q000737:chemistry*; D005978:Glutathione / Q000737:chemistry*; D006179:Gyrus Cinguli / Q000473:pathology; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D008297:Male; D008875:Middle Aged; D015233:Models, Statistical; D013997:Time Factors
chemical_list: D018698:Glutamic Acid; D005978:Glutathione