title: Comparison of compliance for colorectal cancer screening and surveillance by colonoscopy based on risk.
abstract: OBJECTIVE
  To compare colonoscopy screening/surveillance rates by level of risk for colorectal cancer based on age, personal history of adenomatous polyps or colorectal cancer, or family history of colorectal cancer.
  
  
  METHODS
  Participants were aged 30-90 years, were seen within 5 years at Intermountain Healthcare, and had family history in the Utah Population Database. Colonoscopy rates were measured for those with/without risk factors.
  
  
  RESULTS
  Among those aged 60-69 years, 48.4% had colonoscopy in the last 10 years, with rates declining after age 70 years. Percentages of those having had a colonoscopy in the last 10 years generally increased by risk level from 38.5% in those with a familial relative risk <1.0 to 47.6% in those with a familial relative risk >3.0. Compared with those with no family history, the odds ratio for being screened according to guidelines was higher for those with one first-degree relative diagnosed with colorectal cancer ≥ 60 years or two affected second-degree relatives (1.54, 95% confidence interval: 1.46-1.61) than those with one affected first-degree relative diagnosed <60 years or ≥2 affected first-degree relatives (1.25, 95% confidence interval: 1.14-1.37).
  
  
  CONCLUSIONS
  Compliance with colonoscopy guidelines was higher for those with familial risk but did not correspond with the degree of risk.
authors.affiliation: Department of Biomedical Informatics, University of Utah, School of Medicine, Salt Lake City, Utah 84112-5750, USA. d.p.taylor@utah.edu
authors.forename: David P
authors.initials: DP
authors.lastname: Taylor
authors.forename: Lisa A
authors.initials: LA
authors.lastname: Cannon-Albright
authors.forename: Carol
authors.initials: C
authors.lastname: Sweeney
authors.forename: Marc S
authors.initials: MS
authors.lastname: Williams
authors.forename: Peter J
authors.initials: PJ
authors.lastname: Haug
authors.forename: Joyce A
authors.initials: JA
authors.lastname: Mitchell
authors.forename: Randall W
authors.initials: RW
authors.lastname: Burt
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003113:Colonoscopy / Q000706:statistics & numerical data*; D015179:Colorectal Neoplasms / Q000175:diagnosis / Q000517:prevention & control*; D005260:Female; D006801:Humans; D008297:Male; D008403:Mass Screening / Q000706:statistics & numerical data*; D008875:Middle Aged; D016017:Odds Ratio; D010349:Patient Compliance; D017410:Practice Guidelines as Topic; D012307:Risk Factors