title: [Inflammatory control on lifestyle-related diseases and bone metabolism].
abstract: Recent findings suggest that chronic inflammation is involved in lifestyle related diseases and osteoporosis. Members of nuclear receptor superfamily have regulatory effects on inflammatory processes and cytokine responses which contribute to prevention and treatment of above diseases. Here, recent studies are described that these nuclear receptors have regulatory roles called transrepression in chronic inflammatory diseases through their interactions with transcription factors and cell-signaling systems.
authors.affiliation: Department of Geriatric Medicine, The University of Tokyo.
authors.forename: Sumito
authors.initials: S
authors.lastname: Ogawa
authors.forename: Yasuyoshi
authors.initials: Y
authors.lastname: Ouchi
mesh_terms: D001842:Bone and Bones / Q000378:metabolism*; D016207:Cytokines / Q000502:physiology; D006801:Humans; D007249:Inflammation / Q000378:metabolism* / Q000503:physiopathology*; D018836:Inflammation Mediators / Q000502:physiology; D008019:Life Style; D018160:Receptors, Cytoplasmic and Nuclear / Q000502:physiology; D015398:Signal Transduction / Q000502:physiology; D014157:Transcription Factors / Q000502:physiology
chemical_list: D016207:Cytokines; D018836:Inflammation Mediators; D018160:Receptors, Cytoplasmic and Nuclear; D014157:Transcription Factors