title: New concepts in intestinal imaging for inflammatory bowel diseases.
abstract: In the last decade, multiple imaging technologies have been developed that improve visualization of the mucosal, mural, and perienteric inflammation associated with inflammatory bowel diseases. Whereas these technologies have traditionally been used to detect and stage suspected enteric inflammation, we review new, emerging roles in detecting clinically occult inflammation (in asymptomatic patients) and inflammatory complications, predicting response prior to therapy, assessing response after therapy, and enteric healing. We compare the relative performance of these technologies in detecting inflammation, focusing on their advantages and disadvantages and how they might complement each other. We also discuss their potential benefits for patients and clinical trials, reviewing technologic developments and areas of research that could provide important insights into the pathophysiology of inflammatory bowel diseases-related enteric inflammation.
authors.affiliation: Department of Radiology, Mayo Clinic, Rochester, Minnesota, USA. fletcher.joel@mayo.edu
authors.forename: Joel G
authors.initials: JG
authors.lastname: Fletcher
authors.forename: Jeff L
authors.initials: JL
authors.lastname: Fidler
authors.forename: David H
authors.initials: DH
authors.lastname: Bruining
authors.forename: James E
authors.initials: JE
authors.lastname: Huprich
mesh_terms: D000284:Administration, Oral; D053704:Capsule Endoscopy; D003287:Contrast Media / Q000008:administration & dosage; D019160:Endosonography; D005471:Fluoroscopy; D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000175:diagnosis*; D007422:Intestines / Q000000981:diagnostic imaging / Q000473:pathology; D008279:Magnetic Resonance Imaging; D011829:Radiation Dosage; D011877:Radionuclide Imaging; D018570:Risk Assessment; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography
chemical_list: D003287:Contrast Media