title: [Anesthetic treatment of patients with osteogenesis imperfecta].
abstract: OBJECTIVE
  Although the prevalence of osteogenesis imperfecta is low, the effect of this hereditary disease on patients' quality of life is considerable. We report our experience in the perioperative management of patients with this condition in our hospital.
  
  
  METHODS
  Retrospective study describing the interventions on patients with this disease in our hospital from 1991 to 2009. We analyzed demographic data, disease variants, concomitant disorders, surgical procedures, type of anesthesia, and intraoperative and postoperative complications.
  
  
  RESULTS
  From 1991 to 2009, 105 procedures were performed on 29 patients (ages 1 to 25 years) with osteogenesis imperfecta (37.9% women and 62.1% men). The most common type of osteogenesis imperfecta was type III (65.5%). Most patients (93%) had no associated diseases. Two patients were allergic to latex. No complications occurred in 62% of interventions. Reported complications during surgery were 1 case of non-malignant hyperthermia and 1 contralateral femur fracture.
  
  
  CONCLUSIONS
  The prevalence of osteogenesis imperfecta is low. Treatment requires a multidisciplinary approach, in which appropriate perioperative management must be based on a proper understanding of the skeletal and extraskeletal abnormalities associated with this disease.
authors.affiliation: Servicio de Anestesiología y Reanimación, Hospital Universitario de Getafe, Madrid.
authors.forename: W
authors.initials: W
authors.lastname: Engel Espinosa
authors.forename: B
authors.initials: B
authors.lastname: Arrázola Cabrera
authors.forename: P
authors.initials: P
authors.lastname: Peralta Rodríguez
authors.forename: M C
authors.initials: MC
authors.lastname: Fernández Izquierdo
authors.forename: C
authors.initials: C
authors.lastname: García Molina
authors.forename: E
authors.initials: E
authors.lastname: Ortigosa Solórzano
mesh_terms: D000293:Adolescent; D000328:Adult; D000758:Anesthesia / Q000379:methods; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D010013:Osteogenesis Imperfecta; D012189:Retrospective Studies; D055815:Young Adult