title: Clinical evidence in concurrence of retinitis pigmentosa and glaucoma.
abstract: Glaucoma is rarely complicated by retinitis pigmentosa (RP). To provide clinical evidences for this rare situation, we report the concurrence of these two diseases in two children of a Chinese family. In the present two-child Chinese family without positive history, the older sister presented with bilateral sector RP and coexisting chronic angle-closure glaucoma, and the brother with bilateral whole RP but without coexisting glaucoma. Clinical evidences in concurrence of variants of RP and glaucoma because of possible different gene mutations from the same genetic background represent a rare situation, which may provide clues for future researches in molecular pathogenesis of these rare diseases.
authors.affiliation: Department of Ophthalmology, the Second Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.
authors.forename: Mei
authors.initials: M
authors.lastname: Wang
authors.forename: Hao-tian
authors.initials: HT
authors.lastname: Lin
authors.forename: Yu-jing
authors.initials: YJ
authors.lastname: Bai
authors.forename: Jian
authors.initials: J
authors.lastname: Ge
authors.forename: Ye-hong
authors.initials: YH
authors.lastname: Zhuo
mesh_terms: D005260:Female; D005901:Glaucoma / Q000175:diagnosis*; D006801:Humans; D012174:Retinitis Pigmentosa / Q000175:diagnosis*; D055815:Young Adult