title: Generation and reactivity of aza-oxyallyl cationic intermediates: aza-[4 + 3] cycloaddition reactions for heterocycle synthesis.
abstract: Aza-[4 + 3] cycloadditions of putative aza-oxyallyl cationic intermediates and cyclic dienes are reported. The intermediate is generated by the dehydrohalogenation of α-haloamides. The reaction is general to a variety of α-haloamides and is diastereoselective. Computational and experimental data suggest that an N-alkoxy substituent stabilizes the aza-oxyallyl cationic intermediate.
authors.affiliation: Department of Chemistry, University of Nevada-Reno, Reno, Nevada 89557, USA. cjeffrey@unr.edu
authors.forename: Christopher S
authors.initials: CS
authors.lastname: Jeffrey
authors.forename: Korry L
authors.initials: KL
authors.lastname: Barnes
authors.forename: John A
authors.initials: JA
authors.lastname: Eickhoff
authors.forename: Christopher R
authors.initials: CR
authors.lastname: Carson