title: Statin therapy in the perioperative period.
abstract: Statins are frequently used as chronic therapy for reducing cardiovascular mortality and morbidity, but there has been less emphasis on the role of statins in the perioperative period. This review evaluates data regarding statin use in vascular and noncardiac surgery, the use of statins in combination with β-blockers in the perioperative period, perioperative statin use in patients already treated with statins, and the safety of statin therapy in the perioperative period. Current recommendations state that patients who are prescribed statins as chronic therapy should continue treatment in the perioperative period, but data suggest that there may be benefit from the use of perioperative statins in a wider population.
authors.affiliation: Department of Cardiovascular Medicine, Lenox Hill Hospital, New York, NY, USA
authors.forename: Jeffrey S
authors.initials: JS
authors.lastname: Lander
authors.forename: Neil L
authors.initials: NL
authors.lastname: Coplan
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000009:adverse effects / Q000627:therapeutic use*; D059035:Perioperative Period; D017410:Practice Guidelines as Topic; D018570:Risk Assessment; D013514:Surgical Procedures, Operative / Q000009:adverse effects; D016896:Treatment Outcome; D014656:Vascular Surgical Procedures
chemical_list: D000319:Adrenergic beta-Antagonists; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors