title: Genome sequence of the abyssomicin- and proximicin-producing marine actinomycete Verrucosispora maris AB-18-032.
abstract: Verrucosispora maris AB-18-032 is a marine actinomycete that produces atrop-abyssomicin C and proximicin A, both of which have novel structures and modes of action. In order to understand the biosynthesis of these compounds, to identify further biosynthetic potential, and to facilitate rational improvement of secondary metabolite titers, we have sequenced the complete 6.7-Mb genome of Verrucosispora maris AB-18-032.
authors.affiliation: College of Life Sciences and Biotechnology, Korea University, Anam-Dong, Seongbuk-Gu, Seoul, South Korea.
authors.forename: Hanseong
authors.initials: H
authors.lastname: Roh
authors.forename: Gabriel C
authors.initials: GC
authors.lastname: Uguru
authors.forename: Hyeok-Jin
authors.initials: HJ
authors.lastname: Ko
authors.forename: Sujin
authors.initials: S
authors.lastname: Kim
authors.forename: Byung-Yong
authors.initials: BY
authors.lastname: Kim
authors.forename: Michael
authors.initials: M
authors.lastname: Goodfellow
authors.forename: Alan T
authors.initials: AT
authors.lastname: Bull
authors.forename: Kyoung Heon
authors.initials: KH
authors.lastname: Kim
authors.forename: Mervyn J
authors.initials: MJ
authors.lastname: Bibb
authors.forename: In-Geol
authors.initials: IG
authors.lastname: Choi
authors.forename: James E M
authors.initials: JE
authors.lastname: Stach
mesh_terms: D000970:Antineoplastic Agents / Q000378:metabolism; D019086:Bridged Bicyclo Compounds, Heterocyclic / Q000378:metabolism; D004269:DNA, Bacterial / Q000737:chemistry* / Q000235:genetics*; D016680:Genome, Bacterial; D008848:Micromonosporaceae / Q000235:genetics* / Q000302:isolation & purification / Q000378:metabolism; D008969:Molecular Sequence Data; D009429:Netropsin / Q000031:analogs & derivatives / Q000378:metabolism; D017422:Sequence Analysis, DNA; D014871:Water Microbiology
chemical_list: D000970:Antineoplastic Agents; D019086:Bridged Bicyclo Compounds, Heterocyclic; D004269:DNA, Bacterial; C509797:abyssomicin C; C529559:proximicin A; D009429:Netropsin