title: Pantothenic acid supplementation to support rumen microbes?
abstract: Based on repeatedly reported extensive pantothenic acid disappearance in the rumen, the present study is aimed at examining if pantothenic acid is used for a more efficient ruminal fermentation and microbial growth in an artificial rumen (Rusitec). Three substrates differing in roughage/concentrate ratio were incubated with and without the addition of Ca-D-pantothenate. Pantothenic acid was extensively degraded without notably influencing fermentation, microbial protein synthesis and the status of other B-vitamins such as riboflavin, vitamin B6 and niacin. Therefore, pantothenic acid supplementation cannot be expected to contribute to microbial benefit for the ruminant animal.
authors.affiliation: Department of Animal Science, Georg-August-University of Goettingen, Germany.
authors.forename: Denise
authors.initials: D
authors.lastname: Völker
authors.forename: Liane
authors.initials: L
authors.lastname: Hüther
authors.forename: Gürbüz
authors.initials: G
authors.lastname: Daş
authors.forename: Hansjörg
authors.initials: H
authors.lastname: Abel
mesh_terms: D000818:Animals; D001419:Bacteria / Q000187:drug effects*; D003470:Culture Media / Q000032:analysis*; D008954:Models, Biological; D010205:Pantothenic Acid / Q000494:pharmacology*; D012417:Rumen / Q000382:microbiology*; D014803:Vitamin B Complex / Q000494:pharmacology*
chemical_list: D003470:Culture Media; D014803:Vitamin B Complex; D010205:Pantothenic Acid