title: Severe pneumonia and jaundice in a young man: an atypical presentation of an uncommon disease.
abstract: We present a patient with an atypical presentation of Fusobacterium infection, the genus responsible for Lemierre's syndrome. This syndrome, which often affects healthy, young people and can be fatal if not recognized and treated early, is defined as a history of recent oropharyngeal infection with clinical or radiological evidence of internal jugular vein thrombosis and isolation of anaerobic pathogens, mainly Fusobacterium necrophorum. The history, presentation, investigations and management of the patient are described and then contrasted with the existing literature surrounding Lemierre's syndrome, once termed the 'forgotten disease'.
authors.affiliation: The Monsall Unit, Department of Infectious Diseases and Tropical Medicine, North Manchester General Hospital, Manchester, UK.
authors.forename: T
authors.initials: T
authors.lastname: Wingfield
authors.affiliation: The Monsall Unit, Department of Infectious Diseases and Tropical Medicine, North Manchester General Hospital, Manchester, UK.
authors.forename: T J
authors.initials: TJ
authors.lastname: Blanchard
authors.affiliation: The Monsall Unit, Department of Infectious Diseases and Tropical Medicine, North Manchester General Hospital, Manchester, UK.
authors.forename: K M B
authors.initials: KMB
authors.lastname: Ajdukiewicz
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D002097:C-Reactive Protein / Q000032:analysis; D005675:Fusobacterium necrophorum / Q000302:isolation & purification*; D006801:Humans; D007565:Jaundice / Q000150:complications* / Q000175:diagnosis*; D057831:Lemierre Syndrome / Q000175:diagnosis* / Q000382:microbiology / Q000473:pathology*; D007958:Leukocyte Count; D008111:Liver Function Tests; D008297:Male; D018410:Pneumonia, Bacterial / Q000150:complications* / Q000175:diagnosis*
chemical_list: D000900:Anti-Bacterial Agents; D002097:C-Reactive Protein