title: [Effects of inhaled corticosteroids/long-acting beta-2 agonist fix combinations in COPD].
abstract: Chronic obstructive pulmonary disease (COPD) is an inflammatory disease characterized with progressive air flow limitation, and is expected to be the third leading cause of death until 2030 worldwide. The clinical trials in the last 10 years revealed that fix combinations (inhaled corticosteroids/long-acting beta-2 agonist; ICS/LABA) improve lung functions and quality of life, and reduced symptoms and exacerbation rates in patients with severe and very severe COPD.
authors.affiliation: Clinic of Chest Diseases, Umraniye Training and Research Hospital, Istanbul, Turkey.
authors.forename: Tunçalp
authors.initials: T
authors.lastname: Demir
authors.forename: Hakan
authors.initials: H
authors.lastname: Günen
authors.forename: Mehmet
authors.initials: M
authors.lastname: Polatlı
authors.forename: Nurhayat
authors.initials: N
authors.lastname: Yıldırım
mesh_terms: D000280:Administration, Inhalation; D000305:Adrenal Cortex Hormones / Q000008:administration & dosage*; D058666:Adrenergic beta-2 Receptor Agonists / Q000008:administration & dosage*; D003692:Delayed-Action Preparations; D004338:Drug Combinations; D006801:Humans; D008168:Lung / Q000187:drug effects / Q000503:physiopathology; D029424:Pulmonary Disease, Chronic Obstructive / Q000188:drug therapy* / Q000503:physiopathology; D011788:Quality of Life; D012720:Severity of Illness Index
chemical_list: D000305:Adrenal Cortex Hormones; D058666:Adrenergic beta-2 Receptor Agonists; D003692:Delayed-Action Preparations; D004338:Drug Combinations