title: Carotid intima-media thickness is increased not only in non-alcoholic fatty liver disease patients but also in alcoholic fatty liver patients.
abstract: OBJECTIVE
  There are many reports of non-alcoholic fatty liver disease (NAFLD) patients with increased carotid intima-media thickness (IMT). However, there is little information about carotid IMT in alcoholic fatty liver disease (AFLD) patients. We aimed to compare the carotid IMT of NAFLD patients and AFLD patients.
  
  
  METHODS
  The medical records of individuals who underwent carotid IMT measurement and abdominal ultrasonography between January 2006 and December 2008 at Korea University Ansan Hospital were retrospectively reviewed. The patients were divided into group A (no fatty liver without alcohol history), group B (NAFLD), group C (AFLD) and group D (no fatty liver with alcohol history). The carotid IMT results were compared across all groups.
  
  
  RESULTS
  The mean carotid IMT was 0.55 ± 0.1 mm for group A, 0.6 ± 0.1 mm for group B, 0.59 ± 0.1 mm for group C, and 0.54 ± 0.1 mm for group D. There were significant differences between groups A and B, groups A and C, and groups C and D (p < 0.05), but there were no differences between groups B and C (p = 0.736).
  
  
  CONCLUSIONS
  We determined that patients with fatty livers have an increased carotid IMT both in NAFLD and AFLD patients.
authors.affiliation: Division of Gastroenterology and Hepatology, Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea. 93haan@hanmail.net
authors.forename: Jeong Han
authors.initials: JH
authors.lastname: Kim
authors.forename: Seung Young
authors.initials: SY
authors.lastname: Kim
authors.forename: Eun Seok
authors.initials: ES
authors.lastname: Jung
authors.forename: Sung Woo
authors.initials: SW
authors.lastname: Jung
authors.forename: Ja Seol
authors.initials: JS
authors.lastname: Koo
authors.forename: Ji Hoon
authors.initials: JH
authors.lastname: Kim
authors.forename: Jong Eun
authors.initials: JE
authors.lastname: Yeon
authors.forename: So Young
authors.initials: SY
authors.lastname: Kwon
authors.forename: Sang Woo
authors.initials: SW
authors.lastname: Lee
authors.forename: Kwan Soo
authors.initials: KS
authors.lastname: Byun
authors.forename: Chang Hong
authors.initials: CH
authors.lastname: Lee
mesh_terms: D000328:Adult; D000410:Alanine Transaminase / Q000097:blood; D000428:Alcohol Drinking; D000704:Analysis of Variance; D001219:Aspartate Aminotransferases / Q000097:blood; D001663:Bilirubin / Q000097:blood; D001786:Blood Glucose / Q000378:metabolism; D015992:Body Mass Index; D059168:Carotid Intima-Media Thickness; D016893:Carotid Stenosis / Q000209:etiology*; D048909:Diabetes Complications / Q000378:metabolism; D005234:Fatty Liver / Q000150:complications* / Q000378:metabolism; D005235:Fatty Liver, Alcoholic / Q000150:complications / Q000378:metabolism; D005260:Female; D006442:Glycated Hemoglobin / Q000378:metabolism; D006801:Humans; D008075:Lipoproteins, HDL / Q000097:blood; D008297:Male; D024821:Metabolic Syndrome / Q000150:complications / Q000378:metabolism; D008875:Middle Aged; D012189:Retrospective Studies; D014280:Triglycerides / Q000097:blood; D014527:Uric Acid / Q000097:blood; D055105:Waist Circumference; D005723:gamma-Glutamyltransferase / Q000097:blood
chemical_list: D000410:Alanine Transaminase; D001219:Aspartate Aminotransferases; D001663:Bilirubin; D001786:Blood Glucose; D006442:Glycated Hemoglobin; D008075:Lipoproteins, HDL; D014280:Triglycerides; D014527:Uric Acid; D005723:gamma-Glutamyltransferase; C517652:hemoglobin A1c protein, human