title: DNA methylation: a transcriptional mechanism co-opted by the developed mammalian brain?
abstract: Forming and maintaining behavioral memories is a complex process that involves, among other requirements, transcriptional regulation and systems communication. Here we review recent studies exploring the role of DNA methylation in these critical processes. Further, we suggest that, perhaps, the adult brain controls and utilizes the mechanism of DNA methylation in non-traditional ways that are waiting to be explored.
authors.affiliation: Department of Metabolism & Aging, The Scripps Research Institute, Jupiter, FL, USA.
authors.forename: Mikael A
authors.initials: MA
authors.lastname: Mikaelsson
authors.forename: Courtney A
authors.initials: CA
authors.lastname: Miller
mesh_terms: D000818:Animals; D001921:Brain / Q000254:growth & development*; D019175:DNA Methylation; D015254:DNA Modification Methylases / Q000235:genetics; D044127:Epigenesis, Genetic; D005786:Gene Expression Regulation; D018507:Gene Expression Regulation, Developmental; D005824:Genetics, Behavioral; D017774:Long-Term Potentiation / Q000235:genetics; D008568:Memory; D014158:Transcription, Genetic
chemical_list: D015254:DNA Modification Methylases