title: Treatment strategies for sarcopenia and frailty.
abstract: Sarcopenia is the key feature of frailty in older people and a major determinant of adverse health outcomes such as functional limitations and disability. Resistance training and adequate protein and energy intake are the key strategies for the management of sarcopenia. Management of weight loss and resistance training are the most relevant protective countermeasures to slow down the decline of muscle mass and muscle strength. The quality of amino acids in the diet is an important factor for stimulating protein synthesis. Vitamin D deficiency should be treated, and new pharmacologic approaches for sarcopenia are currently assessed.
authors.affiliation: Inserm U1027, F-31073, Avenue Jules Guesdes, University of Toulouse III, F-31073, France. rolland.y@chu-toulouse.fr
authors.forename: Yves
authors.initials: Y
authors.lastname: Rolland
authors.forename: Charlotte
authors.initials: C
authors.lastname: Dupuy
authors.forename: Gabor
authors.initials: G
authors.lastname: Abellan van Kan
authors.forename: Sophie
authors.initials: S
authors.lastname: Gillette
authors.forename: Bruno
authors.initials: B
authors.lastname: Vellas
mesh_terms: D000058:Accidental Falls / Q000517:prevention & control; D000368:Aged; D000975:Antioxidants / Q000627:therapeutic use*; D004044:Dietary Proteins / Q000008:administration & dosage*; D015444:Exercise; D016330:Frail Elderly; D015577:Geriatric Assessment / Q000379:methods; D006293:Health Promotion / Q000379:methods*; D006801:Humans; D008019:Life Style; D018908:Muscle Weakness / Q000209:etiology / Q000517:prevention & control*; D011502:Protein-Energy Malnutrition / Q000150:complications / Q000517:prevention & control; D055070:Resistance Training / Q000379:methods; D055948:Sarcopenia / Q000209:etiology / Q000628:therapy*
chemical_list: D000975:Antioxidants; D004044:Dietary Proteins