title: v-erb A and v-erb B do not cooperate in quail myoblasts.
abstract: We have previously shown that v-erb A stimulates quail myoblast differentiation in a T3 independent, cell-specific manner. In this work, we have studied the influence of v-erb B (the second oncogene carried in the AEV genome) upon quail myoblast proliferation and differentiation. v-erb B expression,moderately stimulates myoblast proliferation, and inhibits differentiation. Moreover, this oncoprotein fully inhibits the v-erb A myogenic influence. These data provide evidence that these two oncogenes do not cooperate in avian myoblasts. Consequently, in contrast to results obtained in other cell-types, coexpression of both oncogenes does not transform quail myoblasts.
authors.affiliation: INRA,LAB DIFFERENCIAT CELLULAIRE & CROISSANCE,UNITE ENDOCRINOL CELLULAIRE,F-34060 MONTPELLIER 1,FRANCE. ECOLE NORMALE SUPER LYON,INRA,LAB BIOL MOL & CELLULAIRE,CNRS,UMR 40,F-69364 LYON,FRANCE.
authors.forename: I
authors.initials: I
authors.lastname: Cassarmalek
authors.forename: S
authors.initials: S
authors.lastname: Marchal
authors.forename: P
authors.initials: P
authors.lastname: Rochard
authors.forename: C
authors.initials: C
authors.lastname: Wrutniak
authors.forename: J
authors.initials: J
authors.lastname: Samarut
authors.forename: G
authors.initials: G
authors.lastname: Cabello