title: Gold nanorods 3D-supercrystals as surface enhanced Raman scattering spectroscopy substrates for the rapid detection of scrambled prions.
abstract: Highly organized supercrystals of Au nanorods with plasmonic antennae enhancement of electrical field have made possible fast direct detection of prions in complex biological media such as serum and blood. The nearly perfect three-dimensional organization of nanorods render these systems excellent surface enhanced Raman scattering spectroscopy substrates with uniform electric field enhancement, leading to reproducibly high enhancement factor in the desirable spectral range.
authors.affiliation: Departamento de Química-Física and Unidad Asociada Consejo Superior de Investigaciones Cientificas-Universidade de Vigo, 36310 Vigo, Spain. ramon.alvarez@uvigo.es
authors.forename: Ramón A
authors.initials: RA
authors.lastname: Alvarez-Puebla
authors.forename: Ashish
authors.initials: A
authors.lastname: Agarwal
authors.forename: Pramit
authors.initials: P
authors.lastname: Manna
authors.forename: Bishnu P
authors.initials: BP
authors.lastname: Khanal
authors.forename: Paula
authors.initials: P
authors.lastname: Aldeanueva-Potel
authors.forename: Enrique
authors.initials: E
authors.lastname: Carbó-Argibay
authors.forename: Nicolas
authors.initials: N
authors.lastname: Pazos-Pérez
authors.forename: Leonid
authors.initials: L
authors.lastname: Vigderman
authors.forename: Eugene R
authors.initials: ER
authors.lastname: Zubarev
authors.forename: Nicholas A
authors.initials: NA
authors.lastname: Kotov
authors.forename: Luis M
authors.initials: LM
authors.lastname: Liz-Marzán
mesh_terms: D003460:Crystallization; D006046:Gold / Q000737:chemistry*; D006801:Humans; D043942:Nanotubes; D011328:Prions / Q000032:analysis* / Q000097:blood; D013059:Spectrum Analysis, Raman / Q000379:methods*
chemical_list: D011328:Prions; D006046:Gold