title: The value of systematic pattern analysis in FNAC of breast lesions: 225 cases with cytohistological correlation.
abstract: BACKGROUND
  Fine needle aspiration cytology (FNAC) has a high rating in the assessment of breast lesions. Various methods have been used to diagnose cytology of breast lesions.
  
  
  OBJECTIVE
  Present study was undertaken to evaluate the feasibility of application of systematic pattern analysis based on morphology in diagnosing breast aspirates.
  
  
  METHODS
  This is a retrospective study of FNAC of the breast done over a period of 4 years in a tertiary care centre. A total of 225 cases of breast lesions for which FNAC was done with histological follow-up were included in the study. Breast aspirates were provisionally diagnosed based on systematic pattern analysis. Aspirates were grouped into six categories based on predominant cellular pattern, and correlation between cytological and histological diagnosis was assessed.
  
  
  RESULTS
  Application of pattern analysis on FNAC of breast lesions in our study had a sensitivity of 94.5%, specificity of 98%, diagnostic accuracy of 97%, positive predictive value of 95.8%, and negative predictive value of 97.4%.
  
  
  CONCLUSIONS
  Systematic pattern analysis based on morphology of FNAC smears was found to be highly reliable and could be easily reproducible in the assessment of breast masses.
authors.affiliation: Department of Pathology, Vinayaka Missions Medical College, Seeragapadi, Salem - 636 306, Tamil Nadu, India.
authors.forename: Prakash H
authors.initials: PH
authors.lastname: Muddegowda
authors.forename: Jyothi B
authors.initials: JB
authors.lastname: Lingegowda
authors.forename: Ramkumar
authors.initials: R
authors.lastname: Kurpad
authors.forename: Pg
authors.initials: P
authors.lastname: Konapur
authors.forename: As
authors.initials: A
authors.lastname: Shivarudrappa
authors.forename: Pm
authors.initials: P
authors.lastname: Subramaniam