title: Mucormycosis of the anterior chest wall presenting as a soft tissue tumour.
abstract: Mucormycosis is a fungal infection caused by order Mucorales in humans. It commonly affects immunocompromised individuals, usually following trauma, and is associated with high rates of mortality despite the use of modern antifungal therapy and debridement. This report describes a case of the mucormycosis that presented as a non-healing ulcer over the chest wall (an extremely rare site for this lesion) which appeared to be a soft tissue tumour. The patient was immunocompetent and had no history of trauma. Repeated biopsies suggested there were only inflammatory changes but a fungal culture confirmed Rhizopus microsporus. The ulcer was managed successfully with high doses of intravenous Amphotericin B and aggressive surgical debridement.
authors.affiliation: Maulana Azad Medical College, New Delhi, India. sudhirkumar11@gmail.com
authors.forename: S K
authors.initials: SK
authors.lastname: Jain
authors.forename: R C M
authors.initials: RC
authors.lastname: Kaza
authors.forename: R
authors.initials: R
authors.lastname: Tanwar
mesh_terms: D000666:Amphotericin B / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D003131:Combined Modality Therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D009091:Mucormycosis / Q000175:diagnosis* / Q000188:drug therapy / Q000601:surgery; D012883:Skin Ulcer / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology* / Q000601:surgery; D012983:Soft Tissue Neoplasms / Q000175:diagnosis*; D035441:Thoracic Wall / Q000382:microbiology*; D014945:Wound Healing
chemical_list: D000900:Anti-Bacterial Agents; D000666:Amphotericin B