title: Phosphorus-containing polymers: a great opportunity for the biomedical field.
abstract: This Review is focused on the growing interest brought to phosphorus-containing organic materials for applications in the biomedical field, mainly because of their properties such as biocompatibility, hemocompatibility, and protein adsorption resistance. It mainly describes relevant works achieved on these materials for various applications: dentistry, regenerative medicine, and drug delivery. Special attention was given to 2-methacryloyloxyethyl phosphorylcholine (MPC) monomer as the latter appeared of great importance because of its biomimetic structure due to the presence of the phospholipid group on its structure. As a result, much research effort is currently concentrated on the development of phosphorylcholine-containing (co)polymers that represent a promising class of materials.
authors.affiliation: Institut Charles Gerhardt Montpellier, Equipe Ingénierie et Architectures Macromoléculaires, Université Montpellier II cc1702, Montpellier Cedex 5, France. Sophie.Monge-Darcos@univ-montp2.fr
authors.forename: Sophie
authors.initials: S
authors.lastname: Monge
authors.forename: Benjamin
authors.initials: B
authors.lastname: Canniccioni
authors.forename: Alain
authors.initials: A
authors.lastname: Graillot
authors.forename: Jean-Jacques
authors.initials: JJ
authors.lastname: Robin
mesh_terms: D001672:Biocompatible Materials / Q000138:chemical synthesis* / Q000378:metabolism; D003813:Dentistry / Q000379:methods*; D016503:Drug Delivery Systems / Q000379:methods*; D006801:Humans; D020100:Hydrogels / Q000737:chemistry / Q000378:metabolism; D008689:Methacrylates / Q000138:chemical synthesis* / Q000378:metabolism; D010710:Phosphates / Q000737:chemistry / Q000378:metabolism; D010743:Phospholipids / Q000737:chemistry / Q000378:metabolism; D010758:Phosphorus / Q000737:chemistry* / Q000378:metabolism; D010767:Phosphorylcholine / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000378:metabolism; D011108:Polymers / Q000737:chemistry; D011506:Proteins / Q000737:chemistry / Q000378:metabolism; D044968:Regenerative Medicine / Q000379:methods*; D013499:Surface Properties; D023822:Tissue Engineering / Q000379:methods*
chemical_list: D001672:Biocompatible Materials; D020100:Hydrogels; D008689:Methacrylates; D010710:Phosphates; D010743:Phospholipids; D011108:Polymers; D011506:Proteins; D010767:Phosphorylcholine; D010758:Phosphorus; C070638:2-methacryloyloxyethyl phosphorylcholine