title: A study on antimicrobial susceptibility pattern in clinical isolates of Staphylococcus aureus in Eritrea.
abstract: BACKGROUND
  Staphylococcus aureus is a major pathogen in skin and soft tissue infections. Methicillin resistant S.aureus (MRSA) is prevalent in most of the countries wherever it is sought for. MRSA is one of the important pathogens implicated in hospital acquired infection. The main objectives of this study was to find out the antimicrobial susceptibility pattern of S.aureus isolates, the prevalence of methicillin resistant S.aureus (MRSA) and nasal carriage rate in healthy hospital staff.
  
  
  METHODS
  A total of 278 S.aureus strains isolated from clinical specimens were tested for antimicrobial susceptibility and 30 anterior nares swabs from healthy hospital staff were screened for S.aureus organisms using standard methods.
  
  
  RESULTS
  High resistance was observed against ampicillin, penicillin and tetracycline. High sensitivity was recorded against amikasin, amoxicillin-c and ciprofloxacin. Of the 278 isolates 26 (9%) isolates were methicillin resistant S.aureus (MRSA). 17 % of the hospital staff were positive for nasal carriage of Staphylococcus aureus .
  
  
  CONCLUSIONS
  Our study emphasizes the need for continuous monitoring of the antimicrobial susceptibility pattern of S.aureus isolates including MRSA for the selection of appropriate therapy. In Eritrea, from the present findings it appears that the spread of MRSA in community and hospital settings is limited.
authors.affiliation: Microbiologist/Associate Professor, College of Health Sciences, Asmara, Eritrea.
authors.forename: Durgadas
authors.initials: D
authors.lastname: Naik
authors.forename: Alem
authors.initials: A
authors.lastname: Teclu