title: Pilot dietary study with normoproteic protein-redistributed plant-food diet and motor performance in patients with Parkinson's disease.
abstract: Although a plant-based diet can provide some benefits in Parkinson's disease (PD), no study to date has evaluated the effectiveness of a plant-food diet in the management of the disease. In this pilot study, we compared the effect of a plant-food menu (PFD) and of a omnivorous menu on motor performance of 25 PD patients, 12 in the intervention group (PDi) and 13 in the control group (PDc). After 4 weeks, the PDi group showed a significant reduction (Mann-Whitney test) in the Unified Parkinson's Disease Rating Scale, total score (47.67 vs. 74.46, P = 0.008) and sub-score III motor performances (25.42 vs. 46.46, P = 0.001), and the modified Hoehn and Yahr Staging Scale (1.96 vs. 3.15, P = 0.005). These data suggest that PFD may be useful in the management of PD patients by improving their motor performances. Additional studies are needed in order to confirm these preliminary results.
authors.affiliation: Department of Neurorehabilitation, Villa Salus Hospital, Venice-Mestre, Italy. luciana_baroni@yahoo.it
authors.forename: Luciana
authors.initials: L
authors.lastname: Baroni
authors.forename: Chiara
authors.initials: C
authors.lastname: Bonetto
authors.forename: Francesca
authors.initials: F
authors.lastname: Tessan
authors.forename: Dario
authors.initials: D
authors.lastname: Goldin
authors.forename: Lorenzo
authors.initials: L
authors.lastname: Cenci
authors.forename: Patrizia
authors.initials: P
authors.lastname: Magnanini
authors.forename: Giovanni
authors.initials: G
authors.lastname: Zuliani
mesh_terms: D000368:Aged; D004032:Diet; D004043:Dietary Fiber / Q000008:administration & dosage; D005260:Female; D005502:Food; D006801:Humans; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000178:diet therapy*; D010865:Pilot Projects; D014674:Plant Proteins, Dietary / Q000008:administration & dosage*; D011597:Psychomotor Performance / Q000187:drug effects*; D016896:Treatment Outcome
chemical_list: D004043:Dietary Fiber; D014674:Plant Proteins, Dietary