title: Stochastic modeling of animal epidemics using data collected over three different spatial scales.
abstract: A stochastic, spatial, discrete-time, SEIR model of avian influenza epidemics among poultry farms in Pennsylvania is formulated. Using three different spatial scales wherein all the birds within a single farm, ZIP code, or county are clustered into a single point, we obtain three different views of the epidemics. For each spatial scale, two parameters within the viral-transmission kernel of the model are estimated using simulated epidemic data. We show that simulated epidemics modeled using data collected on the farm and ZIP-code levels behave similar to the actual underlying epidemics, but this is not true using data collected on the county level. Such analyses of data collected on different spatial scales are useful in formulating intervention strategies to control an ongoing epidemic (e.g., vaccination schedules and culling policies).
authors.affiliation: School of Veterinary Medicine, University of Pennsylvania, Kennett Square, PA 19348, USA. rorres@vet.upenn.edu
authors.forename: Chris
authors.initials: C
authors.lastname: Rorres
authors.forename: Sky T K
authors.initials: ST
authors.lastname: Pelletier
authors.forename: Gary
authors.initials: G
authors.lastname: Smith
mesh_terms: D000822:Animal Husbandry; D000818:Animals; D003198:Computer Simulation; D004195:Disease Models, Animal; D004196:Disease Outbreaks; D005843:Geography; D005585:Influenza in Birds / Q000453:epidemiology* / Q000635:transmission*; D016013:Likelihood Functions; D008954:Models, Biological; D010414:Pennsylvania / Q000453:epidemiology; D011200:Poultry; D013269:Stochastic Processes