title: Emergency department visits for antiviral adverse events during the 2009 H1N1 influenza pandemic.
abstract: The 2009 pandemic influenza A (H1N1) outbreak was associated with an increased use of antiviral agents and highlighted the role of population-based monitoring for related adverse drug events (ADEs). An ongoing, nationally representative emergency department-based surveillance system was used to identify and characterize ADEs during the pandemic. Active surveillance for ADEs successfully provided timely, population-based data during the pandemic. Increases in antiviral ADEs paralleled increases in prescribing. Type and severity of ADEs were similar across all seasons.
authors.affiliation: Centers for Disease Control and Prevention, National Center for Emerging and Zoonotic Infectious Diseases, Division of Healthcare Quality Promotion, Atlanta, GA 30333, USA.
authors.forename: Maribeth C
authors.initials: MC
authors.lastname: Lovegrove
authors.forename: Nadine
authors.initials: N
authors.lastname: Shehab
authors.forename: Craig M
authors.initials: CM
authors.lastname: Hales
authors.forename: Kathy
authors.initials: K
authors.lastname: Poneleit
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Crane
authors.forename: Daniel S
authors.initials: DS
authors.lastname: Budnitz
mesh_terms: D000293:Adolescent; D000328:Adult; D016907:Adverse Drug Reaction Reporting Systems; D000368:Aged; D000998:Antiviral Agents / Q000009:adverse effects*; D002648:Child; D004196:Disease Outbreaks; D064420:Drug-Related Side Effects and Adverse Reactions / Q000453:epidemiology*; D004636:Emergency Service, Hospital / Q000706:statistics & numerical data*; D005260:Female; D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype; D007251:Influenza, Human / Q000188:drug therapy* / Q000821:virology; D008297:Male; D008875:Middle Aged; D010045:Outpatients; D011159:Population Surveillance; D014481:United States / Q000453:epidemiology
chemical_list: D000998:Antiviral Agents