title: A comparison of cerebral vasomotor reactivity in diabetic and nondiabetic Iranian patients.
abstract: BACKGROUND
  Cerebral microangiopathy is one of the most important complications in diabetes. It may interfere with cerebral vasomotor reactivity (VMR) which may lead to disability, stroke or even death. The aim of the present study was to determine and compare VMR changes in diabetic and non- diabetic patients.
  
  
  METHODS
  Fifty three diabetic and 51 non- diabetic patients (with no other vascular abnormality) were recruited. Vasomotor reactivity was evaluated with Trans- Cranial Doppler (TCD) before and after CO2 inhalation.
  
  
  RESULTS
  There were 69 (66.30%) males. The mean age was 41.53 ± 17.80 years. The general average of VMR was 5.79 ± 3.00%, the figures in diabetic and nondiabetic patients were 5.31 ± 2.60% and 6.62 ± 2.00%, respectively (p = 0.02). The average of flow velocity (FV) change was 42.47± 29.00 in diabetics and 53.34 ±16.70 in non- diabetic patients (p = 0.04).
  
  
  CONCLUSIONS
  It is recommended that such non- invasive method is necessary for evaluation of cerebral vasculature in diabetic patients for better prevention.
authors.affiliation: Assistant Professor of Neurology, Department of Neurology of Rasool Akram Hospital, Iran University of Medical Sciences, Tehran, Iran.
authors.forename: Mehdi
authors.initials: M
authors.lastname: Moghaddasi
authors.forename: Mansoureh
authors.initials: M
authors.lastname: Mamarabadi
authors.forename: Amir Hosein
authors.initials: AH
authors.lastname: Habibi