title: Interaction of β-lactam carbenes with 3,6-diphenyltetrazines: a five-step cascade reaction for the direct construction of indeno[2,1-b]pyrrol-2-ones.
abstract: A study of the nucleophilic addition of β-lactam carbenes to 3,6-diphenyltetrazines is reported. Instead of the formation of pyrazole derivatives like most reactions between nucleophilic or ambiphilic carbenes and 3,6-disubstituted tetrazines, β-lactam carbenes reacted with 3,6-diphenyltetrazines to produce indeno[2,1-b]pyrrol-2-ones in good yields. The reaction proceeds most probably through a five-step cascade process. This work has not only provided a one-pot operation for the efficient construction of mutisubstituted indeno[2,1-b]pyrrol-2-ones but also revealed the nucleophilicity of β-lactam carbenes.
authors.affiliation: College of Chemistry, Beijing Normal University, Beijing, China.
authors.forename: Juan
authors.initials: J
authors.lastname: Xing
authors.forename: Xiao-Rong
authors.initials: XR
authors.lastname: Wang
authors.forename: Cai-Xia
authors.initials: CX
authors.lastname: Yan
authors.forename: Ying
authors.initials: Y
authors.lastname: Cheng