title: Prognostic value of plasma pro-adrenomedullin and antithrombin levels in neonatal sepsis.
abstract: The aim of this study was to clarify the prognostic value of serum pro-Adrenomedullin level (pro-ADM) and Anti thrombin level in neonatal sepsis. 40 term neonates with sepsis were enrolled in this study including 20 cases with mild sepsis and 20 cases with severe sepsis. Twenty healthy matched neonates served as a control group. Serum levels of Pro ADM and Antithrombin were measured in all patients and the control group. Serum Pro ADM level was higher in neonates with sepsis than control group, higher in severe than mild sepsis, and was higher in non survivors. Antithrombin concentrations were lower in sepsis cases than control, lower in severe than mild sepsis, and lower in non-survivors.
authors.affiliation: Department of Pediatrics, Faculty of Medicine, Tanta University, Egypt.
authors.forename: Adel A
authors.initials: AA
authors.lastname: Hagag
authors.forename: Heba S
authors.initials: HS
authors.lastname: Elmahdy
authors.forename: Aml A
authors.initials: AA
authors.lastname: Ezzat
mesh_terms: D053607:Adrenomedullin / Q000097:blood*; D058833:Antithrombin Proteins / Q000378:metabolism*; D002097:C-Reactive Protein / Q000378:metabolism; D016022:Case-Control Studies; D006801:Humans; D007231:Infant, Newborn; D011379:Prognosis; D011498:Protein Precursors / Q000097:blood*; D018805:Sepsis / Q000097:blood* / Q000175:diagnosis
chemical_list: D058833:Antithrombin Proteins; D011498:Protein Precursors; C088633:proadrenomedullin; D053607:Adrenomedullin; D002097:C-Reactive Protein