title: Cell-permeable iminocoumarine-based fluorescent dyes for mitochondria.
abstract: A class of small molecule fluorophores, 2-iminocoumarin-3-carboxamide derivatives, has been developed by a rapid microwave-assisted process. These fluorescent probes are cell membrane permeable with low cytotoxicity and able to selectively stain organelles in living cells.
authors.affiliation: State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, P R China.
authors.forename: Diliang
authors.initials: D
authors.lastname: Guo
authors.forename: Tao
authors.initials: T
authors.lastname: Chen
authors.forename: Deju
authors.initials: D
authors.lastname: Ye
authors.forename: Jinyi
authors.initials: J
authors.lastname: Xu
authors.forename: Hualiang
authors.initials: H
authors.lastname: Jiang
authors.forename: Kaixian
authors.initials: K
authors.lastname: Chen
authors.forename: Hui
authors.initials: H
authors.lastname: Wang
authors.forename: Hong
authors.initials: H
authors.lastname: Liu
mesh_terms: D002462:Cell Membrane / Q000187:drug effects / Q000378:metabolism*; D003374:Coumarins / Q000138:chemical synthesis* / Q000737:chemistry; D005456:Fluorescent Dyes / Q000138:chemical synthesis* / Q000737:chemistry; D006367:HeLa Cells; D006801:Humans; D008928:Mitochondria / Q000378:metabolism*; D015394:Molecular Structure
chemical_list: D003374:Coumarins; D005456:Fluorescent Dyes