title: Isolated orbito-cerebral mucormycosis.
abstract: Rhino-orbito-cerebral mucormycosis is a fatal infection in immunocompromised hosts. Prompt recognition of this clinical condition is essential for early diagnosis to avoid a delay of treatment. The presence of black eschar, usually in the nasal cavity, is the most alerting sign to the diagnosis. We present a patient with extremely fulminant ROCM in which the disease might be acquired via an orbital infection without nasal or paranasal involvement. With black eschars appearing at the bilateral canthi as the first alarm to extensive vascular involvement, the lethal infection rapidly evolved to occlusion of the bilateral ophthalmic arteries and eventually major intracranial arteries.
authors.affiliation: Department of Neurology, Shin Kong Wu Ho-Su Memorial Hospital.
authors.forename: Chi-Ieong
authors.initials: CI
authors.lastname: Lau
authors.forename: Han-Cheng
authors.initials: HC
authors.lastname: Wang
authors.forename: Hsu-Ling
authors.initials: HL
authors.lastname: Yeh
authors.forename: Chen-Hsien
authors.initials: CH
authors.lastname: Li
mesh_terms: D000328:Adult; D001927:Brain Diseases / Q000175:diagnosis* / Q000473:pathology*; D005123:Eye / Q000098:blood supply / Q000473:pathology; D017809:Fatal Outcome; D006801:Humans; D016867:Immunocompromised Host; D008297:Male; D009091:Mucormycosis / Q000175:diagnosis* / Q000401:mortality / Q000473:pathology*; D009668:Nose Diseases / Q000175:diagnosis / Q000473:pathology; D009916:Orbital Diseases / Q000175:diagnosis* / Q000473:pathology*