title: Lobar distribution of cerebral microbleeds: the Rotterdam Scan Study.
abstract: OBJECTIVE
  To investigate the distribution of lobar microbleeds over the different lobes, taking into account lobar volume and clustering effects of multiple microbleeds.
  
  
  METHODS
  Population-based, cross-sectional analysis.
  
  
  METHODS
  The Rotterdam Scan Study.
  
  
  METHODS
  A total of 198 persons (age range, 61-95 years) with lobar microbleeds.
  
  
  METHODS
  Distribution of microbleeds over different lobes.
  
  
  RESULTS
  We found that lobar cerebral microbleeds occurred significantly more often in the temporal lobe, a region known to be more affected in cerebral amyloid angiopathy.
  
  
  CONCLUSIONS
  This study corroborates the presumed association of lobar microbleeds with cerebral amyloid angiopathy.
authors.affiliation: Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam, the Netherlands.
authors.forename: Dymph J
authors.initials: DJ
authors.lastname: Mesker
authors.forename: Mariëlle M F
authors.initials: MM
authors.lastname: Poels
authors.forename: M Arfan
authors.initials: MA
authors.lastname: Ikram
authors.forename: Meike W
authors.initials: MW
authors.lastname: Vernooij
authors.forename: Albert
authors.initials: A
authors.lastname: Hofman
authors.forename: Henri A
authors.initials: HA
authors.lastname: Vrooman
authors.forename: Aad
authors.initials: A
authors.lastname: van der Lugt
authors.forename: Monique M B
authors.initials: MM
authors.lastname: Breteler
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D016657:Cerebral Amyloid Angiopathy / Q000150:complications* / Q000175:diagnosis* / Q000453:epidemiology; D002540:Cerebral Cortex / Q000098:blood supply*; D002543:Cerebral Hemorrhage / Q000150:complications* / Q000175:diagnosis* / Q000453:epidemiology; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008833:Microcirculation; D008875:Middle Aged; D009426:Netherlands / Q000453:epidemiology; D009929:Organ Size; D013702:Temporal Lobe / Q000098:blood supply