title: Fresh-frozen human bone graft to repair defect after mandibular giant follicular cyst removal: a case report.
abstract: The purpose of this article is to report the clinical, radiographical and histological findings about a case of a young woman affected by a mandibular giant follicular cyst. Conservative tumor resection was followed by immediate reconstructive treatment using fresh frozen human bone graft, instead of autologous bone graft, as material for bone regeneration. Follicular cyst is a benign, non invasive lesion with slow but progressive growth. Radiological and histological examination of the lesion confirmed the presence of a follicular cyst which underwent biopsy evaluation before enucleation. According to literature, conservative treatment was performed with optimal prognosis. At 24 months post surgery no evidence of recurrency was objective; the CT scan revealed optimal bone formation inside the reconstructed site. The use of fresh frozen bone allograft, thanks to its osteoinductive and osteoconductive properties, can be a safe choice for reconstruction of bone defects after jaw cysts removal.
authors.affiliation: Department of Surgery, Section of Oral and Maxillofacial Surgery, University of Verona, Policlinico Giovanni Battista Rossi, Piazzale Ludovico Antonio Scuro, 10, 37134, Verona, Italy.
authors.forename: Massimo
authors.initials: M
authors.lastname: Albanese
authors.forename: Pasquale
authors.initials: P
authors.lastname: Procacci
authors.forename: Guido
authors.initials: G
authors.lastname: Sancassani
authors.forename: Pier Francesco
authors.initials: PF
authors.lastname: Nocini
mesh_terms: D020341:Absorbable Implants; D000293:Adolescent; D057005:Bioengineering; D001861:Bone Regeneration; D016025:Bone Transplantation; D005260:Female; D005497:Follicular Cyst / Q000000981:diagnostic imaging / Q000601:surgery*; D005615:Freezing; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008334:Mandible / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery*; D011300:Preoperative Care; D014057:Tomography, X-Ray Computed; D014945:Wound Healing