title: A case of Hashimoto encephalopathy: clinical manifestation, imaging, pathology, treatment, and prognosis.
abstract: BACKGROUND
  Hashimoto encephalopathy is a rare encephalopathy with positive antithyroid antibodies and normal thyroid function. We describe the clinical manifestations, neuroimaging, and histopathologic changes in a 52-year-old female with Hashimoto encephalopathy.
  
  
  RESULTS
  The neuroimaging changes are multifocal abnormalities in cortical and subcortical areas bilaterally not enhanced by gadolinium. After high doses of corticosteroid therapy, the changes rapidly disappeared with marked improvement of clinical symptoms.
  
  
  CONCLUSIONS
  This case shows the importance of assessment of antithyroid antibodies in patients with rapidly progressive cognitive dysfunction with/without the history of abnormality of thyroid function.
authors.affiliation: Department of Neurology, Beijing Friendship Hospital, Capital Medical University, Beijing, China. zhao_weiqin@yahoo.com
authors.forename: Weiqin
authors.initials: W
authors.lastname: Zhao
authors.forename: Jimei
authors.initials: J
authors.lastname: Li
authors.forename: Jiawei
authors.initials: J
authors.lastname: Wang
authors.forename: Yanjun
authors.initials: Y
authors.lastname: Guo
authors.forename: Houzhen
authors.initials: H
authors.lastname: Tuo
authors.forename: Zhimin
authors.initials: Z
authors.lastname: Kang
authors.forename: Bin
authors.initials: B
authors.lastname: Jiang
authors.forename: Rui
authors.initials: R
authors.lastname: Wang
authors.forename: Dexin
authors.initials: D
authors.lastname: Wang
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use*; D001323:Autoantibodies / Q000097:blood; D001921:Brain / Q000473:pathology; D001927:Brain Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology / Q000503:physiopathology; D004569:Electroencephalography; D004660:Encephalitis; D005260:Female; D050031:Hashimoto Disease / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D008875:Middle Aged; D011379:Prognosis; D013961:Thyroid Gland / Q000276:immunology; D016896:Treatment Outcome
chemical_list: D000305:Adrenal Cortex Hormones; D001323:Autoantibodies