title: Postoperative radiotherapy in prostate cancer: acquired certainties and still open issues. A review of recent literature.
abstract: It is recognized that radiation therapy can eradicate microscopic tumor disease, even in postoperative prostate cancer patients, when extracapsular extension, positive surgical margins or increased prostate-specific antigen is found in surgical specimens. This review of recent literature analyzes and discusses acquired certainties and still open questions regarding type, timing, doses, techniques, toxicities, and associated hormonal therapies of radiotherapy prescribed after radical prostatectomy.
authors.affiliation: Radiotherapy and Radiosurgery, IRCCS Istituto Clinico Humanitas, Rozzano, Milano, Italy. filippoalongi@libero.it
authors.forename: Filippo
authors.initials: F
authors.lastname: Alongi
authors.forename: Cesare
authors.initials: C
authors.lastname: Cozzarini
authors.forename: Nadia
authors.initials: N
authors.lastname: Di Muzio
authors.forename: Marta
authors.initials: M
authors.lastname: Scorsetti
mesh_terms: D014408:Biomarkers, Tumor / Q000097:blood; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology / Q000528:radiation effects; D008207:Lymphatic Metastasis; D008297:Male; D009367:Neoplasm Staging; D018579:Patient Selection; D010388:Pelvis; D017430:Prostate-Specific Antigen / Q000097:blood; D011468:Prostatectomy / Q000379:methods; D011471:Prostatic Neoplasms / Q000276:immunology / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery; D011879:Radiotherapy Dosage; D018714:Radiotherapy, Adjuvant / Q000379:methods; D016032:Randomized Controlled Trials as Topic; D016879:Salvage Therapy
chemical_list: D014408:Biomarkers, Tumor; D017430:Prostate-Specific Antigen