title: Advances in surgical treatment of colorectal liver metastases.
abstract: Colorectal cancer is the 3rd most common malignant neoplasm in the West. About 50% of patients develop liver metastases throughout the course of the disease. Those are responsible for at least two-thirds of deaths. Advances in surgical techniques and improvement in chemotherapy regimens have allowed offering treatment with curative intent to an increasing number of patients. This article reviews recent advances in the treatment of liver metastases, including strategies to increase resection (e.g., portal vein embolization, radiofrequency ablation, two-stage hepatectomy, conversion therapy and reverse treatment strategy) and hepatectomy in the presence of extrahepatic disease. Finally, the results of surgical treatment of liver metastases at the Hospital A.C. Camargo are briefly shown.
authors.affiliation: Departamento de Cirurgia Abdominal, Hospital AC Camargo, São Paulo, SP.
authors.forename: Felipe José Fernández
authors.initials: FJ
authors.lastname: Coimbra
authors.forename: Thiago Costa
authors.initials: TC
authors.lastname: Pires
authors.forename: Wilson Luiz da
authors.initials: WL
authors.lastname: Costa Junior
authors.forename: Alessandro Landskron
authors.initials: AL
authors.lastname: Diniz
authors.forename: Héber Salvador de Castro
authors.initials: HS
authors.lastname: Ribeiro
mesh_terms: D015179:Colorectal Neoplasms; D006498:Hepatectomy; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary* / Q000601:surgery*