title: [Differences between observed and estimated by hematocrit hemoglobin and its relevance in the diagnosis of anemia among coastal population in Venezuela: analysis of the second national study of human growth and development (SENACREDH)].
abstract: OBJECTIVE
  To evaluate the differences between the observed hemoglobin levels and those estimated based on hematocrit in the context of the 2nd National Study of Human Growth and Development of the Venezuelan Population (SENACREDH).
  
  
  METHODS
  6,004 individuals were chosen by a probabilistic multistage cluster sampling representing 7,286,781 inhabitants from North Central Coastal area (Vargas, Carabobo, Capital District, Aragua and Miranda). Means of observed and estimated hemoglobin (hematocrit/3) were compared, using t test for related samples and linear regression.
  
  
  RESULTS
  Mean difference between the values of observed and estimated hemoglobin was -0.3446 ±0.0002 (p<0.001); significantly overestimating the hemoglobin values. Regression models of hemoglobin on hematocrit showed an r2=0,87. In order to correct the estimation, we propose a new formula for calculating hemoglobin based on haematocrit values: estimated hemoglobin=(Haematocrit/3.135)+ 0.257.
  
  
  CONCLUSIONS
  There is an overestimation of hemoglobin levels from hematocrit levels and therefore an underestimation of the prevalence of anemia; however, a high positive correlation between them was found, allowing modeling for achieving a better estimation of the hemoglobin from the hematocrit value.
authors.affiliation: Ministerio del Poder Popular para las Comunas y Protección Social, Caracas, Venezuela.
authors.forename: Jessica
authors.initials: J
authors.lastname: Flores-Torres
authors.forename: María
authors.initials: M
authors.lastname: Echeverría-Ortega
authors.forename: Melissa
authors.initials: M
authors.lastname: Arria-Bohorquez
authors.forename: Glida
authors.initials: G
authors.lastname: Hidalgo
authors.forename: Carlos
authors.initials: C
authors.lastname: Albano-Ramos
authors.forename: Rafael
authors.initials: R
authors.lastname: Sanz
authors.forename: Alfonso J
authors.initials: AJ
authors.lastname: Rodríguez-Morales
mesh_terms: D000293:Adolescent; D000328:Adult; D000740:Anemia / Q000097:blood* / Q000175:diagnosis*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006400:Hematocrit; D006454:Hemoglobins / Q000032:analysis*; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D014687:Venezuela; D055815:Young Adult
chemical_list: D006454:Hemoglobins