title: How deficient are vitamin D deficient critically ill patients?
abstract: Vitamin D deficiency is highly prevalent among critically ill patients and may be associated with adverse outcomes. Failure of conventional vitamin D supplementation in correcting deficiency has called for studies to evaluate the efficacy and safety of a high-dose regime in critically ill patients. High-dose vitamin D supplementation that corrects a deficient state effectively and safely allows for intervention studies to be undertaken to determine the impact of vitamin D on morbidity and mortality in critically ill patients.
authors.affiliation: Department of Diabetes and Endocrinology, Princess Alexandra Hospital, School of Medicine, University of Queensland, 199 Ipswich Road, Woolloongabba, Brisbane, Queensland, Australia 4102. p.lee@garvan.org.au
authors.forename: Paul
authors.initials: P
authors.lastname: Lee
mesh_terms: D002762:Cholecalciferol / Q000627:therapeutic use*; D003422:Critical Care / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D014808:Vitamin D Deficiency / Q000188:drug therapy*; D014815:Vitamins / Q000627:therapeutic use*
chemical_list: D014815:Vitamins; D002762:Cholecalciferol