title: Schistosomiasis and signet ring cell carcinoma of the rectum.
abstract: A definitive link between Schistosoma hematobium infection and squamous cell carcinoma of the bladder has been identified. A weaker association between S japonicum infection and colorectal neoplasia has been proposed, although reports are limited to case reports, a case series, and epidemiologic studies. Virtually all cases presented in the literature describe intestinal-type adenocarcinoma occurring in association with S japonicum. We here describe a 40-year-old male Filipino patient with signet ring cell carcinoma of the rectum and evidence of infection by S japonicum.
authors.affiliation: Department of Pathology, University of California, San Diego, 92103, USA.
authors.forename: Mariana
authors.initials: M
authors.lastname: Canepa
authors.forename: Paul T
authors.initials: PT
authors.lastname: Fanta
authors.forename: Noel
authors.initials: N
authors.lastname: Weidner
authors.forename: Michael R
authors.initials: MR
authors.lastname: Peterson
mesh_terms: D000328:Adult; D000818:Animals; D000871:Anthelmintics / Q000627:therapeutic use; D018279:Carcinoma, Signet Ring Cell / Q000188:drug therapy / Q000469:parasitology* / Q000473:pathology; D003125:Colostomy; D006801:Humans; D008297:Male; D020360:Neoadjuvant Therapy; D011223:Praziquantel / Q000627:therapeutic use; D012004:Rectal Neoplasms / Q000188:drug therapy / Q000469:parasitology* / Q000473:pathology; D012549:Schistosoma japonicum / Q000302:isolation & purification*; D012554:Schistosomiasis japonica / Q000188:drug therapy / Q000469:parasitology* / Q000473:pathology
chemical_list: D000871:Anthelmintics; D011223:Praziquantel