title: [Diffuse anterior retinoblastoma].
abstract: Retinoblastoma is the most common primary intraocular tumor in childhood. Diffuse anterior retinoblastoma is an uncommon variant and usually occurs in comparatively older children. Typically, there is an extensive infiltration of the anterior segment by tumor cells clinically mimicking anterior uveitis with pseudohypopyon. The actual retinal focus is often very small and may not be detected despite a thorough histological examination. In this case report the clinical and histological findings of a diffuse anterior retinoblastoma are described.
authors.affiliation: Emory Eye Center, L.F. Montgomery Laboratory, Emory University, BT 428, 1365 Clifton Road NE, Atlanta, Georgia 30322, USA. martina.c.herwig@emory.edu
authors.forename: M C
authors.initials: MC
authors.lastname: Herwig
authors.forename: G B
authors.initials: GB
authors.lastname: Hubbard
authors.forename: J R
authors.initials: JR
authors.lastname: Wells
authors.forename: H E
authors.initials: HE
authors.lastname: Grossniklaus
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage*; D016190:Carboplatin / Q000008:administration & dosage; D002675:Child, Preschool; D005047:Etoposide / Q000008:administration & dosage; D006801:Humans; D008297:Male; D019572:Retinal Neoplasms / Q000188:drug therapy* / Q000473:pathology*; D012175:Retinoblastoma / Q000188:drug therapy* / Q000473:pathology*; D016896:Treatment Outcome; D014750:Vincristine / Q000008:administration & dosage
chemical_list: D014750:Vincristine; D005047:Etoposide; D016190:Carboplatin