title: The clinical and histologic efficacy of xenograft granules for maxillary sinus floor augmentation.
abstract: The objective of this study was to investigate the potential of xenograft (cancellous bovine bone) granules to form vital bone in non-natural bone-forming areas of maxillary sinuses. Fourteen sinus augmentations were performed in 14 patients. Surgical outcomes were uneventful, and sufficient radiopaque volume was present radiographically to place dental implants in all sites. Clinical reentry at 6 months revealed bone formation at the osteotomy site. Histologic evaluation of the obtained bone cores revealed that xenograft granules were integrated and surrounded by woven bone and lamellar bone that were in close contact with the particles. The average percentage of newly formed bone at 6 months was 27.5% ± 8.9%. Vital bone formation using the xenograft granules was supported by both clinical and histologic evidence.
authors.affiliation: Division of Periodontology, Department of Oral Medicine, Infecti and Immunity, Harvard School of Dental Medicine, Boston, Massachusetts 02115, USA. nevinsperimp@aol.com
authors.forename: Myron
authors.initials: M
authors.lastname: Nevins
authors.forename: Marcelo
authors.initials: M
authors.lastname: Camelo
authors.forename: Nicola
authors.initials: N
authors.lastname: De Angelis
authors.forename: James J
authors.initials: JJ
authors.lastname: Hanratty
authors.forename: Wahn G
authors.initials: WG
authors.lastname: Khang
authors.forename: Jong-Jin
authors.initials: JJ
authors.lastname: Kwon
authors.forename: Giulio
authors.initials: G
authors.lastname: Rasperini
authors.forename: Isabella
authors.initials: I
authors.lastname: Rocchietta
authors.forename: Peter
authors.initials: P
authors.lastname: Schupbach
authors.forename: David M
authors.initials: DM
authors.lastname: Kim
mesh_terms: D000328:Adult; D001861:Bone Regeneration; D018786:Bone Substitutes; D003758:Dental Implantation, Endosseous / Q000379:methods*; D006801:Humans; D008443:Maxillary Sinus / Q000601:surgery*; D008875:Middle Aged; D013516:Oral Surgical Procedures, Preprosthetic / Q000379:methods*
chemical_list: D018786:Bone Substitutes