title: The relationship between serum ferritin and metabolic syndrome in healthy Korean men.
abstract: OBJECTIVE
  Elevated serum ferritin levels have been reported to be associated with several metabolic disorders. We investigated the relationship between serum ferritin level and metabolic syndrome and its components in healthy Korean men.
  
  
  METHODS
  In this cross-sectional study, serum ferritin level and metabolic syndrome and its components were measured from 18 581 men from January to December in 2008. The presence of metabolic syndrome was determined according to the most recent consensus report of the National Cholesterol Education Program's Third Adult Treatment Panel. Logistic regression models were applied to examine the relationship between the serum ferritin level and the metabolic syndrome and its components.
  
  
  RESULTS
  After adjusting for clinical covariates, the odds ratio and 95% confidence intervals of metabolic syndrome with respect to Q2, Q3 and Q4 were 1.34 (1.14-1.57), 1.49 (1.24-1.70) and 1.99 (1.70-2.33), respectively (p for trend < 0.001). The multivariable-adjusted model also showed a significantly graded relationship between individual components of metabolic syndrome and the quartile groups of serum ferritin.
  
  
  CONCLUSIONS
  In this study, elevated ferritin concentration is independently associated with metabolic syndrome and its components among healthy Korean men.
authors.affiliation: Department of Occupational Medicine, Kangbuk Samsung Hospital, School of Medicine, Sungkyunkwan University, Seoul, South Korea.
authors.forename: Jae-Hong
authors.initials: JH
authors.lastname: Ryoo
authors.forename: Min-Gi
authors.initials: MG
authors.lastname: Kim
authors.forename: Da-Woon
authors.initials: DW
authors.lastname: Lee
authors.forename: Ju-Young
authors.initials: JY
authors.lastname: Shin
mesh_terms: D000328:Adult; D044466:Asian People; D003430:Cross-Sectional Studies; D005293:Ferritins / Q000097:blood*; D006801:Humans; D007333:Insulin Resistance; D008297:Male; D024821:Metabolic Syndrome / Q000097:blood*; D008875:Middle Aged; D056910:Republic of Korea
chemical_list: D005293:Ferritins