title: Triggered activity of a nicking endonuclease for mercuric(II) ion-mediated duplex-like DNA cleavage.
abstract: The cleavage activity of a nicking endonuclease towards metal-ion-mediated duplex-like DNA can be triggered by the corresponding metal ions, which was demonstrated with mercuric(II) ion as a model via a simple electrochemical protocol.
authors.affiliation: College of Chemistry, Chemical Engineering and Materials Science, Engineering Research Center of Pesticide and Medicine Intermediate Clean Production, Ministry of Education, Key Laboratory of Molecular and Nano Probes, Ministry of Education, Shandong Normal University, Jinan 250014, China.
authors.forename: Feng
authors.initials: F
authors.lastname: Li
authors.forename: Yan
authors.initials: Y
authors.lastname: Feng
authors.forename: Shufeng
authors.initials: S
authors.lastname: Liu
authors.forename: Bo
authors.initials: B
authors.lastname: Tang
mesh_terms: D002384:Catalysis; D004247:DNA / Q000378:metabolism*; D053837:DNA Cleavage; D003850:Deoxyribonuclease I / Q000378:metabolism; D015252:Deoxyribonucleases, Type II Site-Specific / Q000378:metabolism*; D055664:Electrochemical Techniques; D004566:Electrodes; D006046:Gold / Q000737:chemistry; D007477:Ions / Q000737:chemistry; D008628:Mercury / Q000737:chemistry*
chemical_list: D007477:Ions; D006046:Gold; D004247:DNA; D003850:Deoxyribonuclease I; D015252:Deoxyribonucleases, Type II Site-Specific; C044346:GGATC-specific type II deoxyribonucleases; D008628:Mercury