title: Solvent controlled mechanistic dichotomy in a Au(III)-catalyzed, heterocyclization triggered, Nazarov reaction.
abstract: Tandem Au(III)-catalyzed heterocyclization/Nazarov cyclizations leading to substituted carbocycle fused furans are described. An interesting dichotomy of reaction pathways as a function of solvent, confirmed by the isolation and trapping of reaction intermediates, provided a basis for computational studies that supported the experimental findings.
authors.affiliation: Department of Chemistry and Biochemistry, Florida State University, Tallahassee, FL 32306, USA. mek@chem.fsu.edu
authors.forename: Marie E
authors.initials: ME
authors.lastname: Krafft
authors.forename: Dinesh V
authors.initials: DV
authors.lastname: Vidhani
authors.forename: John W
authors.initials: JW
authors.lastname: Cran
authors.forename: Mariappan
authors.initials: M
authors.lastname: Manoharan
mesh_terms: D002384:Catalysis; D003500:Cyclization; D005663:Furans / Q000737:chemistry; D006046:Gold / Q000737:chemistry*; D012997:Solvents / Q000737:chemistry*
chemical_list: D005663:Furans; D012997:Solvents; D006046:Gold