title: Expression mechanism of human uterine endometrial cancer-specific fucosylated carbohydrate chains - aberrant alpha-1-]4-fucosyl-transferases in uterine endometrial cancer-derived cell-lines with type-I carbohydrate chain.
abstract: Cells of uterine endometrial cancer cell line SNG-II were classified into two groups according to their reactivity with anti-uterine endometrial cancer monoclonal antibody (MSN-1), whose recognition antigen is mainly the Lewis(b) antigens; those that strongly reacted with MSN-1 (SNG-S group) and those that weakly reacted with it (SNG-W group). The SNG-S showed a higher activity of a 1-->4-fucosyltransferase activity than that of the SNG-W. The expression of Lewis(b) antigen was stronger in the SNG-S than that in the SNG-W. Therefore, the expression of uterine endometrial cancer-specific fucosylated carbohydrate could be mainly controlled by alpha-fucosyltransferase activities.
authors.affiliation: GUNMA UNIV,SCH MED,DEPT LEGAL MED,MAEBASHI,TOKYO 371,JAPAN.
authors.forename: K
authors.initials: K
authors.lastname: Kubushiro
authors.forename: K
authors.initials: K
authors.lastname: Tsukazaki
authors.forename: Y
authors.initials: Y
authors.lastname: Sakuma
authors.forename: Y
authors.initials: Y
authors.lastname: Akiba
authors.forename: M
authors.initials: M
authors.lastname: Sakayori
authors.forename: R
authors.initials: R
authors.lastname: Aoki
authors.forename: S
authors.initials: S
authors.lastname: Yazawa
authors.forename: S
authors.initials: S
authors.lastname: Nozawa