title: A longitudinal evaluation of changes in disability and quality of life in a sample of women with migraine.
abstract: Migraine's high prevalence, which rises up to 25% among women in the productive age, determines a strong reduction in health-related quality of life (HRQoL) and increased disability. Aim of this study is to longitudinally describe disability and HRQoL in a sample of adult women with migraine attending to a specialty centre. HRQoL was measured with the SF-36 and disability with the WHO-DAS II. One-sample t test was used to assess deterioration in disability and HRQoL scales compared to normative scores; effect size was calculated to describe magnitude of change after 3 months. Majority of scales were significantly deteriorated, and changes between baseline and follow-up were negligible to small for most of SF-36 scales, and small to moderate for WHO-DAS II scales. In conclusion, women with migraine showed pervasive deterioration in disability and HRQoL. Wider improvements were observed at follow-up for activities in which relational skills are relevant, while those with a physical component, or that are predominantly performed autonomously, remained almost unchanged.
authors.affiliation: Neurology, Public Health and Disability Unit, Neurological Institute C. Besta IRCCS Foundation, Via Celoria 11, 20133 Milan, Italy. araggi@istituto-besta.it
authors.forename: Alberto
authors.initials: A
authors.lastname: Raggi
authors.forename: Matilde
authors.initials: M
authors.lastname: Leonardi
authors.forename: Ambra
authors.initials: A
authors.lastname: Giovannetti
authors.forename: Marcella
authors.initials: M
authors.lastname: Curone
authors.forename: Gennaro
authors.initials: G
authors.lastname: Bussone
authors.forename: Domenico
authors.initials: D
authors.lastname: D'Amico
mesh_terms: D000328:Adult; D000368:Aged; D004185:Disability Evaluation; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008875:Middle Aged; D008881:Migraine Disorders / Q000150:complications / Q000453:epidemiology* / Q000523:psychology; D011788:Quality of Life; D011795:Surveys and Questionnaires; D055815:Young Adult