title: Diffuse optical multipatch technique for tissue oxygenation monitoring: clinical study in intensive care unit.
abstract: Diffuse optical multipatch technique is used to assess spatial variations in absorption and scattering in biological tissue, by monitoring changes in the concentration of oxyhemoglobin and deoxyhemoglobin. In our preliminary study, the temporal tracings of tissue oxygenation are measured using diffuse optical multipatch measurement and a venous occlusion test, employing normal subjects and ICU patients suffering from sepsis and heart failure. In experiments, obvious differences in tissue oxygenation signals were observed among all three groups. This paper discusses the physiological relevance of tissue oxygenation with respect to disease.
authors.affiliation: Department of Photonics, National Chiao Tung University, Hsinchu 30010, Taiwan.
authors.forename: Chun-Yang
authors.initials: CY
authors.lastname: Wang
authors.forename: Ming-Lung
authors.initials: ML
authors.lastname: Chuang
authors.forename: Shinn-Jye
authors.initials: SJ
authors.lastname: Liang
authors.forename: Jui-che
authors.initials: JC
authors.lastname: Tsai
authors.forename: Ching-Cheng
authors.initials: CC
authors.lastname: Chuang
authors.forename: Yao-Sheng
authors.initials: YS
authors.lastname: Hsieh
authors.forename: Chih-Wei
authors.initials: CW
authors.lastname: Lu
authors.forename: Po-Lei
authors.initials: PL
authors.lastname: Lee
authors.forename: Chia-Wei
authors.initials: CW
authors.lastname: Sun
mesh_terms: D003422:Critical Care / Q000379:methods; D003936:Diagnosis, Computer-Assisted / Q000379:methods*; D006333:Heart Failure / Q000097:blood* / Q000175:diagnosis; D006801:Humans; D009391:Nephelometry and Turbidimetry / Q000379:methods*; D010092:Oximetry / Q000379:methods*; D010100:Oxygen / Q000097:blood*; D012031:Refractometry / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D018805:Sepsis / Q000097:blood* / Q000175:diagnosis
chemical_list: D010100:Oxygen