title: [Imported histoplasmosis in Navarra: presentation of four cases].
abstract: OBJECTIVE
  Histoplasmosis is a fungal infection caused by the dimorphic fungi Histoplasma capsulatum. Its incidence in Spain has increased in recent years, mainly due to the increased presence of immigrants from Latin America and increased travel to the continent for tourism and cooperation. Our aim was to review the clinical characteristics of cases of histoplasmosis diagnosed in our hospital during the last six years.
  
  
  METHODS
  We diagnosed 4 cases from 4 patients from South America, 3 of whom were HIV positive and 1 diagnosed with dermatomyositis was treated with immunosuppressive drugs. The laboratory diagnosis was carried out by histological and microbiological study, by culture and specific PCR directly on the sample.
  
  
  CONCLUSIONS
  As it is an imported infection there needs to be a high level of suspicion and a detailed history taken to get a diagnosis. This infection requires a differential diagnosis between febrile syndrome in immunosuppressed patients, both HIV positive and immunosuppressive therapy, which originate from endemic areas, or who have a history of staying in them.
authors.affiliation: Servicio de Microbiología, Complejo Hospitalario de Navarra, Pamplona, España. ana.navascues.ortega@cfnavarra.es
authors.forename: Ana
authors.initials: A
authors.lastname: Navascués
authors.forename: Irene
authors.initials: I
authors.lastname: Rodríguez
authors.forename: Jesús
authors.initials: J
authors.lastname: Repáraz
authors.forename: Soledad
authors.initials: S
authors.lastname: Salvo
authors.forename: Alberto
authors.initials: A
authors.lastname: Gil-Setas
authors.forename: José María
authors.initials: JM
authors.lastname: Martínez Peñuela
mesh_terms: D000328:Adult; D005260:Female; D006660:Histoplasmosis / Q000175:diagnosis*; D006801:Humans; D008297:Male; D008875:Middle Aged; D013020:South America / Q000208:ethnology; D013030:Spain