title: Enantioselective bromoaminocyclization using amino-thiocarbamate catalysts.
abstract: A facile and efficient enantioselective bromoaminocyclization of unsaturated sulfonamides has been developed using an amino-thiocarbamate catalyst. A range of enantioenriched pyrrolidines were prepared with up to 99% yield and 99% ee. The corresponding lactams could be obtained through oxidation of the pyrrolidines.
authors.affiliation: Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543, Singapore.
authors.forename: Ling
authors.initials: L
authors.lastname: Zhou
authors.forename: Jie
authors.initials: J
authors.lastname: Chen
authors.forename: Chong Kiat
authors.initials: CK
authors.lastname: Tan
authors.forename: Ying-Yeung
authors.initials: YY
authors.lastname: Yeung