title: Impact of prenatal diagnosis and therapy on neonatal surgery.
abstract: The field of neonatal surgery is now inextricably linked to the field of obstetrics. Neonatologists and surgical specialists experienced with the postnatal management and outcomes of infants with various disorders now look in utero along with obstetricians and fetal medicine specialists to characterize the development and well-being of fetuses with congenital anomalies with a goal to optimize fetal, perinatal and postnatal management. The purpose of this article is to examine how prenatal diagnosis and therapy has influenced neonatal surgery. An overview of prenatal diagnosis and the evolution of fetal therapy are provided. In addition, we review the impact of prenatal diagnosis and therapy on the management and outcomes of infants with specific anomalies, including congenital lung malformations, sacrococcygeal teratoma, myelomeningocele, giant fetal neck masses, diaphragmatic hernia and congenital heart defects.
authors.affiliation: Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, Texas, USA. dcass@bcm.edu
authors.forename: Darrell L
authors.initials: DL
authors.lastname: Cass
mesh_terms: D000013:Congenital Abnormalities / Q000175:diagnosis* / Q000601:surgery*; D005260:Female; D005315:Fetal Diseases / Q000601:surgery / Q000628:therapy*; D046128:Fetal Therapies / Q000639:trends*; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000601:surgery*; D008297:Male; D011247:Pregnancy; D011296:Prenatal Diagnosis / Q000639:trends*