title: Leser-Trélat Sign without Internal Malignancy.
abstract: Leser-Trélat sign is characterized by the abrupt appearance of multiple seborrheic keratoses in association with underlying malignant disease. A case of Leser-Trélat sign in a 66-year-old healthy woman is presented. Evaluation and follow-up for the development of malignancy over a 2-year period failed to reveal any evidence of malignancy. To date, almost all cases of Leser-Trélat sign have been reported in association with an underlying malignancy. It is less known that Leser-Trélat sign can also occur in healthy individuals in the absence of internal malignancy.
authors.affiliation: Department of Dermatology, Centre Hospitalier de Saint-Brieuc, Saint-Brieuc, France.
authors.forename: Gilles
authors.initials: G
authors.lastname: Safa
authors.forename: Laure
authors.initials: L
authors.lastname: Darrieux