title: [Study on the alkaloids in Stephania hernandifolia].
abstract: OBJECTIVE
  To study the alkaloids in Stephania hernandifolia.
  
  
  METHODS
  The dried herbs of S. hernandifolia were extracted with 95% ethanol. After removal of the solvent, the residue was first partitioned between acid water and petroleum ether, then the aqueous layer was basified and extracted with chloroform to obtain crude alkaloids. Column chromatography on silica gel, Rp-18, MCI CHP 20P, Sephadex LH-20 were applied for the isolation and purification of the crude alkaloids fraction. The structures were elucidated by their physicochemical properties and spectral data.
  
  
  RESULTS
  Six alkaloids were obtained and identified as Cepharamine (I), l-tetrahadropalmatine (II), Plmatine (III), Stephamiersine (IV), Telitoxine (V), Daurioxoisoporphine D (VI).
  
  
  CONCLUSIONS
  Compounds I - VI are isolated from this plant for the first time, and compounds V, VI are isolated from the plants of Stephania for the first time.
authors.affiliation: The Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences, Guiyang 550002, China. tanglijia3518@qq.com
authors.forename: Li-Jia
authors.initials: LJ
authors.lastname: Tang
authors.forename: Huan-Yu
authors.initials: HY
authors.lastname: Guan
authors.forename: Yuan-Hu
authors.initials: YH
authors.lastname: Zhang
authors.forename: Li
authors.initials: L
authors.lastname: He
authors.forename: Xiao-Sheng
authors.initials: XS
authors.lastname: Yang
authors.forename: Xiao-Jiang
authors.initials: XJ
authors.lastname: Hao
mesh_terms: D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification*; D055598:Chemical Phenomena; D002853:Chromatography, Liquid / Q000379:methods; D015394:Molecular Structure; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification*; D010946:Plants, Medicinal / Q000737:chemistry*; D031607:Stephania / Q000737:chemistry*
chemical_list: D000470:Alkaloids; D010936:Plant Extracts