title: Progress in the design and development of phosphoinositide 3-kinase (PI3K) inhibitors for the treatment of chronic diseases.
authors.affiliation: Karus Therapeutics Ltd., 2 Venture Road, Southampton Science Park, Southampton, S016 7NP, UK.
authors.forename: Stephen
authors.initials: S
authors.lastname: Shuttleworth
authors.forename: Franck
authors.initials: F
authors.lastname: Silva
authors.forename: Cyrille
authors.initials: C
authors.lastname: Tomassi
authors.forename: Alexander
authors.initials: A
authors.lastname: Cecil
authors.forename: Thomas
authors.initials: T
authors.lastname: Hill
authors.forename: Helen
authors.initials: H
authors.lastname: Rogers
authors.forename: Paul
authors.initials: P
authors.lastname: Townsend
mesh_terms: D000818:Animals; D002908:Chronic Disease; D015195:Drug Design; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy; D019869:Phosphatidylinositol 3-Kinases / Q000502:physiology; D000081082:Phosphoinositide-3 Kinase Inhibitors; D047428:Protein Kinase Inhibitors / Q000627:therapeutic use*; D015398:Signal Transduction
chemical_list: D019869:Phosphatidylinositol 3-Kinases; D000081082:Phosphoinositide-3 Kinase Inhibitors; D047428:Protein Kinase Inhibitors