title: Functionality of natural killer cells from end-stage cancer patients exposed to coherent electromagnetic fields.
abstract: The main objective of our study is to investigate whether an enhancement of the immune system in end-stage cancer patients is achieved by exposure to coherent electromagnetic fields. For this reason, 15 end-stage cancer patients were exposed at low intensity, coherent electromagnetic fields at radiofrequencies ranging from 600 kHz-729 Hz, for 8 h/day, 6 days/week for 4 weeks. NKs number and cytotoxicity of NK T-lymphocytes versus K562 cancer cell line were estimated by flow cytometry, before and after exposure. Data showed that the exposure of the end-stage cancer patients to the coherent electromagnetic fields resulted in a significant increase of the number and the cytotoxicity of the NK T-lymphocytes against cancer cells, in all patients. Exposure to coherent EMFs at radiofrequencies increases the number and cytotoxicity of NK T-lymphocytes, which may contribute to the improvement of cancer patients' status.
authors.affiliation: Laboratory of Physiology, University of Ioannina, Greece.
authors.forename: Angelos
authors.initials: A
authors.lastname: Evangelou
authors.forename: Ioannis
authors.initials: I
authors.lastname: Toliopoulos
authors.forename: Christos
authors.initials: C
authors.lastname: Giotis
authors.forename: Apostolos
authors.initials: A
authors.lastname: Metsios
authors.forename: Ioannis
authors.initials: I
authors.lastname: Verginadis
authors.forename: Yannis
authors.initials: Y
authors.lastname: Simos
authors.forename: Konstantinos
authors.initials: K
authors.lastname: Havelas
authors.forename: Georgios
authors.initials: G
authors.lastname: Hadziaivazis
authors.forename: Spyridon
authors.initials: S
authors.lastname: Karkabounas
mesh_terms: D000328:Adult; D000368:Aged; D045744:Cell Line, Tumor; D004574:Electromagnetic Fields; D005260:Female; D005434:Flow Cytometry; D006801:Humans; D020014:K562 Cells; D007694:Killer Cells, Natural / Q000276:immunology / Q000378:metabolism / Q000528:radiation effects*; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000145:classification / Q000276:immunology / Q000378:metabolism / Q000532:radiotherapy*; D016879:Salvage Therapy / Q000379:methods*; D013602:T-Lymphocytes, Cytotoxic / Q000276:immunology / Q000378:metabolism / Q000528:radiation effects; D013997:Time Factors