title: Contact and contactless diffuse reflectance spectroscopy: potential for recovery monitoring of vascular lesions after intense pulsed light treatment.
abstract: Optical fiber contact probe diffuse reflectance spectroscopy and remote multispectral imaging methods in the spectral range of 400 to 1100 nm were used for skin vascular malformation assessment and recovery tracing after treatment by intense pulsed light. The results confirmed that oxy-hemoglobin relative changes and the optical density difference between lesion and healthy skin in the spectral region 500 to 600 nm may be successfully used for objective appraisal of the therapy effect. Color redness parameter a* = 2 is suggested as a diagnostic border to distinguish healthy skin and vascular lesions, and as the indicator of phototreatment efficiency. Valuable diagnostic information on large area (>5 mm) lesions and lesions with uncertain borders can be proved by the multispectral imaging method.
authors.forename: Ilona
authors.initials: I
authors.lastname: Kuzmina
authors.forename: Ilze
authors.initials: I
authors.lastname: Diebele
authors.forename: Janis
authors.initials: J
authors.lastname: Spigulis
authors.forename: Lauma
authors.initials: L
authors.lastname: Valeine
authors.forename: Anna
authors.initials: A
authors.lastname: Berzina
authors.forename: Anita
authors.initials: A
authors.lastname: Abelite
mesh_terms: D003116:Color; D004058:Diffusion; D006391:Hemangioma / Q000473:pathology / Q000628:therapy; D006801:Humans; D010789:Phototherapy / Q000379:methods*; D019339:Port-Wine Stain / Q000473:pathology* / Q000628:therapy*; D012867:Skin / Q000473:pathology; D013057:Spectrum Analysis / Q000379:methods*; D013684:Telangiectasis / Q000473:pathology / Q000628:therapy; D016896:Treatment Outcome