title: The influence of subthalamic nucleus deep brain stimulation on physical, emotional, cognitive functions and daily living activities in patients with Parkinson's disease.
abstract: OBJECTIVE
  To describe effectiveness of deep brain stimulation of subthalamic nucleus (DBS STN) on physical, emotional, cognitive functions and daily activities in Parkinson's patients.
  
  
  METHODS
  Ten patients (51.20 ±10.20 yr.) were assessed three times. The Time Up and Go Test, 12 m Walking Test and Chair Stand Test were used to assess mobility and balance. Purdeu Pegboard and hand writing tests were used to evaluate hand function. The Hospital Anxiety and Depression Scale (HAD) was used to detect depressive symptoms and anxiety score. The Unified Parkinson\'s Disease Rating Scale (UPDRS) and Hoehn &Yahr Scale were also used. The Schwab and England Test was used to evaluate the daily activities (ADL).
  
  
  RESULTS
  The results showed that all the patients' mobility and balance ability improved after surgery (p < 0.05). Depressive symptoms / anxiety scores were found to be lower than before surgery (p < 0.05). There were differences in terms of ADL and UPDRS scores after surgery (p < 0.05). At six month after surgery; depressive symptoms decreased by 78%. ADL and UPDRS motor and total scores improved by 190%, 72%, and 78% respectively.
  
  
  CONCLUSIONS
  STN DBS is an effective treatment to improve physical functioning, emotional status and daily activities in Parkinson's patients. However, it did not show any positive effect on cognitive function.
authors.affiliation: Pamukkale University, School of Physical Therapy and Rehabilitation, Denizli, Turkey. fkural@pau.edu.tr
authors.forename: Filiz
authors.initials: F
authors.lastname: Altug
authors.forename: Feridun
authors.initials: F
authors.lastname: Acar
authors.forename: Goksemin
authors.initials: G
authors.lastname: Acar
authors.forename: Ugur
authors.initials: U
authors.lastname: Cavlak
mesh_terms: D000203:Activities of Daily Living; D000328:Adult; D001007:Anxiety / Q000628:therapy; D003071:Cognition; D046690:Deep Brain Stimulation / Q000379:methods*; D003863:Depression / Q000628:therapy; D004644:Emotions; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009043:Motor Activity; D010300:Parkinson Disease / Q000503:physiopathology / Q000523:psychology / Q000628:therapy; D004856:Postural Balance; D020127:Recovery of Function; D020531:Subthalamic Nucleus / Q000502:physiology*; D016896:Treatment Outcome