title: A linkage map of sheep chromosome X (OARX) aligned to human chromosome X (HSAX).
abstract: We have constructed a genetic linkage map of the sheep X chromosome (OARX) containing 22 new gene loci from across the human X chromosome (HSAX). The female OARX linkage map has a total length of 152.6 cM with average gene spacing of 5.5 cM. Comparison with HSAX confirms one previously reported major breakpoint and inversion, and other minor rearrangements between OARX and HSAX. Comparison of the linkage map with sheep sequence data OAR 1.0 reveals a different arrangement of markers on the q arm, which may more accurately reflect the genuine arrangement of this region.
authors.affiliation: AgResearch, Invermay Agricultural Centre, Mosgiel, New Zealand.
authors.forename: M C
authors.initials: MC
authors.lastname: French
authors.forename: K G
authors.initials: KG
authors.lastname: Dodds
authors.forename: G H
authors.initials: GH
authors.lastname: Davis
authors.forename: S M
authors.initials: SM
authors.lastname: Galloway
authors.forename: S J
authors.initials: SJ
authors.lastname: Edwards
mesh_terms: D000818:Animals; D001483:Base Sequence; D002874:Chromosome Mapping; D033481:Chromosomes, Mammalian / Q000235:genetics; D005260:Female; D008040:Genetic Linkage; D005819:Genetic Markers; D006801:Humans; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D020641:Polymorphism, Single Nucleotide; D016415:Sequence Alignment; D034561:Sheep, Domestic / Q000235:genetics*; D014960:X Chromosome / Q000235:genetics*
chemical_list: D005819:Genetic Markers