title: Fertility-sparing surgery for borderline ovarian tumors: oncologic safety and reproductive outcomes.
abstract: BACKGROUND
  To evaluate the oncological safety and reproductive outcomes of patients with borderline ovarian tumors (BOTs) treated with fertility-sparing surgery.
  
  
  METHODS
  Patients with BOTs who underwent radical or fertility-sparing surgery between 1997 and 2009 were identified from an institutional database. The recurrence rates were compared between the 2 surgery groups. To compare the reproductive outcomes, all patients who underwent fertility-sparing surgery were interviewed by telephone.
  
  
  RESULTS
  One hundred forty-three patients underwent radical surgery, and 155 patients underwent fertility-sparing surgery. After a median interval of 38 months from the initial surgery (range, 10-77 months), 19 patients had a recurrence. The recurrence rate was similar in the radical and fertility-sparing surgery groups (4.9% and 7.7%, respectively; P = 0.280). In the fertility-sparing surgery group, however, the main site of recurrence was the remaining ovary that was successfully salvaged with a second round of fertility-sparing surgery. Of 51 patients who attempted to conceive, 45 patients (88.2%) were successful and resulted in 54 term deliveries.
  
  
  CONCLUSIONS
  Fertility-sparing surgery for BOTs is safe and can result in future pregnancies, suggesting that such surgery should be considered for young patients who desire preservation of fertility.
authors.affiliation: Department of Obstetrics and Gynecology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
authors.forename: Taejong
authors.initials: T
authors.lastname: Song
authors.forename: Chel Hun
authors.initials: CH
authors.lastname: Choi
authors.forename: Hwang Shin
authors.initials: HS
authors.lastname: Park
authors.forename: Min-Kyu
authors.initials: MK
authors.lastname: Kim
authors.forename: Yoo-Young
authors.initials: YY
authors.lastname: Lee
authors.forename: Tae-Joong
authors.initials: TJ
authors.lastname: Kim
authors.forename: Jeong-Won
authors.initials: JW
authors.lastname: Lee
authors.forename: Duk-Soo
authors.initials: DS
authors.lastname: Bae
authors.forename: Byoung-Gie
authors.initials: BG
authors.lastname: Kim
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002277:Carcinoma / Q000534:rehabilitation / Q000601:surgery*; D002648:Child; D005260:Female; D005298:Fertility / Q000502:physiology; D013509:Gynecologic Surgical Procedures / Q000009:adverse effects* / Q000379:methods*; D006801:Humans; D007247:Infertility, Female / Q000517:prevention & control*; D010535:Laparoscopy / Q000379:methods; D008875:Middle Aged; D019060:Minimally Invasive Surgical Procedures / Q000379:methods; D010051:Ovarian Neoplasms / Q000534:rehabilitation / Q000601:surgery*; D012098:Reproduction / Q000502:physiology*; D012189:Retrospective Studies; D016896:Treatment Outcome; D055815:Young Adult