title: Synthesis of nine-membered azlactones by palladium-catalyzed ring-expansion of γ-methylidene-δ-valerolactones with aziridines.
abstract: A palladium-catalyzed formal [6 + 3] cyclization of γ-methylidene-δ-valerolactones with aziridines has been developed to produce 1,4-oxazonan-9-ones, a class of nine-membered azlactones that are not easily accessible by existing methods. The products thus obtained can also be further functionalized with ease.
authors.affiliation: Department of Chemistry, Graduate School of Science, Kyoto University, Sakyo, Kyoto, Japan. shintani@kuchem.kyoto-u.ac.jp
authors.forename: Ryo
authors.initials: R
authors.lastname: Shintani
authors.forename: Keiichi
authors.initials: K
authors.lastname: Ikehata
authors.forename: Tamio
authors.initials: T
authors.lastname: Hayashi