title: Partial internal biliary diversion: a solution for intractable pruritus in progressive familial intrahepatic cholestasis type 1.
abstract: Biliary diversion offers a potential option for intractable pruritus in children with chronic cholestatic disorders. Progressive familial intrahepatic cholestasis (PFIC) is an inherited disorder of impaired bile acid transport and excretion, which presents with jaundice and pruritus in the first few months of life and progresses to cirrhosis by infancy or adolescence. We report a child with PFIC type 1 who underwent internal biliary diversion for intractable pruritus and was relieved of his symptoms.
authors.affiliation: Kanchi Kamakoti CHILDS Trust Hospital & The CHILDS Trust Medical Research Foundation, Nungambakkam, Chennai, India. ganeped79@rediffmail.com
authors.forename: Ramaswamy
authors.initials: R
authors.lastname: Ganesh
authors.forename: Natarajan
authors.initials: N
authors.lastname: Suresh
authors.forename: Malathi
authors.initials: M
authors.lastname: Sathiyasekeran
authors.forename: Priya
authors.initials: P
authors.lastname: Ramachandran
mesh_terms: D000714:Anastomosis, Surgical; D001648:Bile Canaliculi / Q000473:pathology; D001662:Biliary Tract Surgical Procedures / Q000379:methods*; D002648:Child; D002780:Cholestasis, Intrahepatic / Q000150:complications / Q000473:pathology / Q000601:surgery*; D006801:Humans; D008099:Liver / Q000473:pathology; D008297:Male; D011537:Pruritus / Q000209:etiology* / Q000601:surgery