title: Drug-eluting stents during ST-segment elevation acute myocardial infarction: a critical analysis.
abstract: Primary percutaneous coronary intervention is the preferred reperfusion therapy for ST-segment elevation acute myocardial infarction patients within 12 hours of symptom-onset. Routine stent implantation during the procedure significantly reduces the rate of target vessel revascularization, although restenosis still represents a current limitation of the technique. Drug-eluting stents were developed to treat and prevent coronary restenosis. Randomized trials, meta-analysis, and registries proved their efficacy and safety in different clinical situations, including acute myocardial infarction. However, the increased risk of late stent thrombosis associated with drug-eluting stents during primary percutaneous coronary interventions encourages a careful analysis to identify which patients most benefit from them, as well as those where a prolonged dual antiplatelet therapy does not represent a limiting factor.
authors.affiliation: Irmandade da Santa Casa de Misericórdia de Marília, Av. Vicente Ferreira 828, Marília, São Paulo, Brazil. pedroberaldo@gmail.com
authors.forename: Pedro Beraldo de
authors.initials: PB
authors.lastname: Andrade
authors.forename: Marden André
authors.initials: MA
authors.lastname: Tebet
authors.forename: Felipe Souza Maia da
authors.initials: FS
authors.lastname: Silva
authors.forename: Mônica Vieira Athanazio de
authors.initials: MV
authors.lastname: Andrade
authors.forename: André
authors.initials: A
authors.lastname: Labrunie
authors.forename: Luiz Alberto
authors.initials: LA
authors.lastname: Piva e Mattos
mesh_terms: D015906:Angioplasty, Balloon, Coronary / Q000379:methods*; D023903:Coronary Restenosis / Q000517:prevention & control*; D054855:Drug-Eluting Stents; D006801:Humans; D009203:Myocardial Infarction / Q000473:pathology / Q000628:therapy*; D018570:Risk Assessment; D013997:Time Factors