title: Synthesis of some phenylpropanoid glycosides (PPGs) and their acetylcholinesterase/xanthine oxidase inhibitory activities.
abstract: In this research, three categories of phenylpropanoid glycosides (PPGs) were designed and synthesized with PPGs isolated from Rhodiola rosea L. as lead compounds. Their inhibitory abilities toward acetylcholinesterase (AChE) and xanthine oxidase (XOD) were also tested. Some of the synthetic PPGs exhibited excellent enzyme inhibitory abilities.
authors.affiliation: School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China.
authors.forename: Xiao-Dong
authors.initials: XD
authors.lastname: Li
authors.forename: Shuai-Tao
authors.initials: ST
authors.lastname: Kang
authors.forename: Guo-Yu
authors.initials: GY
authors.lastname: Li
authors.forename: Xian
authors.initials: X
authors.lastname: Li
authors.forename: Jin-Hui
authors.initials: JH
authors.lastname: Wang
mesh_terms: D000110:Acetylcholinesterase / Q000378:metabolism*; D004791:Enzyme Inhibitors / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D006027:Glycosides / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D010936:Plant Extracts / Q000737:chemistry*; D029771:Rhodiola / Q000737:chemistry*; D014969:Xanthine Oxidase / Q000037:antagonists & inhibitors / Q000378:metabolism*
chemical_list: D004791:Enzyme Inhibitors; D006027:Glycosides; D010936:Plant Extracts; D014969:Xanthine Oxidase; D000110:Acetylcholinesterase