title: Acute onset disseminated superficial porokeratosis associated with exacerbation of diabetes mellitus due to development of anti-insulin antibodies.
abstract: The development of disseminated superficial porokeratosis is occasionally observed in association with renal transplant, autoimmune diseases and various hematological disorders, suggesting a certain immunosuppression may trigger a widespread abnormal keratinization. Here we report a case of sudden onset disseminated superficial porokeratosis associated with an exacerbation of diabetes mellitus due to an anti-insulin antibody formation. To our knowledge, this is the first report of disseminated superficial porokeratosis in a patient with severe diabetes mellitus.
authors.affiliation: Department of Dermatology; University of Occupational and Environmental Health; Kitakyushu, Fukuoka Japan.
authors.forename: Motonobu
authors.initials: M
authors.lastname: Nakamura
authors.forename: Shoko
authors.initials: S
authors.lastname: Fukamachi
authors.forename: Yoshiki
authors.initials: Y
authors.lastname: Tokura