title: The switch-on luminescence sensing of histidine-rich proteins in solution: a further application of a Cu2+ ligand.
abstract: A new probe/Cu(2+) complex for the detection of his-tagged protein has been developed, based on an improved probe, Dansyl-Gly-Py (1), by closely mimicing the structure of a peptide, ATCUN. In aqueous solution, 1/Cu(2+) has good selectivity to histidine and cysteine, and further can detect histidine-rich protein by releasing the quenched fluorescence of 1.
authors.affiliation: State Key Laboratory of Supramolecular Structure and Materials, Jilin University, No. 2699, Qianjin Street, Changchun, 130012, China.
authors.forename: Bin
authors.initials: B
authors.lastname: Wang
authors.forename: Yang
authors.initials: Y
authors.lastname: Gao
authors.forename: Hong-Wei
authors.initials: HW
authors.lastname: Li
authors.forename: Zhi-Peng
authors.initials: ZP
authors.lastname: Hu
authors.forename: Yuqing
authors.initials: Y
authors.lastname: Wu
mesh_terms: D003300:Copper / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000737:chemistry*; D008024:Ligands; D049449:Luminescence; D008958:Models, Molecular; D009842:Oligopeptides / Q000737:chemistry*; D009942:Organometallic Compounds / Q000737:chemistry*; D011506:Proteins / Q000737:chemistry*; D012996:Solutions; D000099053:Histidine-Rich Glycoprotein
chemical_list: D005456:Fluorescent Dyes; D008024:Ligands; D009842:Oligopeptides; D009942:Organometallic Compounds; D011506:Proteins; D012996:Solutions; D000099053:Histidine-Rich Glycoprotein; D003300:Copper