title: Mevalonate pathway is a novel target for hypertension.
authors.forename: Takuya
authors.initials: T
authors.lastname: Kishi
mesh_terms: D019883:Alkyl and Aryl Transferases / Q000378:metabolism; D000818:Animals; D000959:Antihypertensive Agents / Q000627:therapeutic use*; D001013:Aorta, Thoracic / Q000187:drug effects* / Q000378:metabolism / Q000473:pathology / Q000503:physiopathology; D001794:Blood Pressure / Q000187:drug effects; D013186:Farnesyl-Diphosphate Farnesyltransferase / Q000378:metabolism; D051231:Farnesyltranstransferase / Q000378:metabolism; D051228:Geranyltranstransferase / Q000378:metabolism; D006801:Humans; D006903:Hydroxymethylglutaryl CoA Reductases / Q000378:metabolism; D006973:Hypertension / Q000188:drug therapy* / Q000378:metabolism / Q000473:pathology / Q000503:physiopathology; D008798:Mevalonic Acid / Q000378:metabolism*; D009206:Myocardium / Q000378:metabolism* / Q000473:pathology; D015398:Signal Transduction / Q000187:drug effects*; D020257:Ventricular Remodeling / Q000187:drug effects
chemical_list: D000959:Antihypertensive Agents; D006903:Hydroxymethylglutaryl CoA Reductases; D019883:Alkyl and Aryl Transferases; C083291:geranylgeranyltransferase type-I; D051228:Geranyltranstransferase; D013186:Farnesyl-Diphosphate Farnesyltransferase; D051231:Farnesyltranstransferase; D008798:Mevalonic Acid