title: Triterpene cyclases from Oryza sativa L.: cycloartenol, parkeol and achilleol B synthases.
abstract: The gene products of AK121211, AK066327, and AK070534 from Oryza sativa encode cycloartenol, parkeol, and achilleol B synthases, respectively. Parkeol synthase is a unique enzyme that affords parkeol as a single product. Achilleol B synthase is the third seco-type triterpene cyclase identified to date, and triterpenes produced by this synthase include achilleol B (90%), tetracyclic (5.12%) and pentacyclic scaffolds (4.37%), and unidentified triterpenes (0.51%). The pathway for achilleol B biosynthesis is proposed.
authors.affiliation: Department of Applied Biological Chemistry, Faculty of Agriculture, and Graduate School of Science and Technology, Niigata University, Nishi-ku, Niigata, Japan.
authors.forename: Ryousuke
authors.initials: R
authors.lastname: Ito
authors.forename: Kouya
authors.initials: K
authors.lastname: Mori
authors.forename: Ippei
authors.initials: I
authors.lastname: Hashimoto
authors.forename: Chiaki
authors.initials: C
authors.lastname: Nakano
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Sato
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Hoshino
mesh_terms: D019753:Intramolecular Lyases / Q000378:metabolism*; D019751:Intramolecular Transferases / Q000235:genetics / Q000302:isolation & purification / Q000378:metabolism*; D007810:Lanosterol / Q000031:analogs & derivatives / Q000737:chemistry / Q000302:isolation & purification / Q000378:metabolism; D015394:Molecular Structure; D012275:Oryza / Q000201:enzymology* / Q000235:genetics; D010840:Phytosterols / Q000737:chemistry / Q000302:isolation & purification / Q000378:metabolism; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000378:metabolism
chemical_list: D010840:Phytosterols; D014315:Triterpenes; C530507:achilleol B; D007810:Lanosterol; C093882:parkeol; D019751:Intramolecular Transferases; C559534:achilleol B synthase, Oryza sativa; C559557:parkeol synthase, Oryza sativa; C021923:cycloartenol synthase; D019753:Intramolecular Lyases; C040265:pinene cyclase I; C100089:cycloartenol