title: Tambjamine alkaloids and related synthetic analogs: efficient transmembrane anion transporters.
abstract: The tambjamine alkaloids and related synthetic analogs are potent transmembrane anion tranporters promoting bicarbonate/chloride exchange in model phospholipid liposomes and discharging pH gradients in living cells.
authors.affiliation: Department of Pathology and Experimental Therapeutics, Cancer Cell Biology Research Group, Universidad de Barcelona, Barcelona, Spain.
authors.forename: Paulina
authors.initials: P
authors.lastname: Iglesias Hernández
authors.forename: Daniel
authors.initials: D
authors.lastname: Moreno
authors.forename: Anatalia Araujo
authors.initials: AA
authors.lastname: Javier
authors.forename: Tomás
authors.initials: T
authors.lastname: Torroba
authors.forename: Ricardo
authors.initials: R
authors.lastname: Pérez-Tomás
authors.forename: Roberto
authors.initials: R
authors.lastname: Quesada
mesh_terms: D000470:Alkaloids / Q000138:chemical synthesis / Q000737:chemistry* / Q000493:pharmacokinetics*; D001639:Bicarbonates / Q000737:chemistry; D001692:Biological Transport / Q000187:drug effects; D045744:Cell Line, Tumor; D002462:Cell Membrane / Q000737:chemistry / Q000187:drug effects*; D002712:Chlorides / Q000737:chemistry; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008081:Liposomes / Q000737:chemistry*; D008958:Models, Molecular; D015394:Molecular Structure; D010743:Phospholipids / Q000737:chemistry; D011758:Pyrroles / Q000138:chemical synthesis / Q000737:chemistry* / Q000493:pharmacokinetics*
chemical_list: D000470:Alkaloids; D001639:Bicarbonates; D002712:Chlorides; D008081:Liposomes; D010743:Phospholipids; D011758:Pyrroles