title: The 1-year clinical impact of rotational aspiration atherectomy of infrainguinal lesions.
abstract: The present study was carried out to provide information about outcome of the Jetstream atherectomy device for treatment of infrainguinal arteries. From February 2006 to February 2007, 172 patients with Rutherford class 1 to 5 lower limb ischemia were enrolled at 9 study sites. The endpoints were evaluation of quality of life according to the walking impairment questionnaire (WIQ) besides technical parameters. In the total study cohort, the WIQ scale maintained improved up to 12-month follow-up. Furthermore, target lesion revascularization rate was 26% (42/162), ankle-brachial index (ABI) increased from 0.59 ± 0.21 at baseline to 0.82 ± 0.27 (P < 0.05), and mean Rutherford class dropped from 3.0 ± 0.9 at baseline to 1.5 ± 1.3 at 1 year (P < .05). The results of this prospective, multicenter, clinical study demonstrate that the Jetstream atherectomy device is a potential treatment alternative for the endovascular management to improve clinical outcome in patients with peripheral arterial occlusive disease.
authors.affiliation: Department of Angiology, Heart-Centre Bad Krozingen, Germany. Sebastian.sixt@herzzentrum.de
authors.forename: Sebastian
authors.initials: S
authors.lastname: Sixt
authors.forename: Aljoscha
authors.initials: A
authors.lastname: Rastan
authors.forename: Dierk
authors.initials: D
authors.lastname: Scheinert
authors.forename: Hans
authors.initials: H
authors.lastname: Krankenberg
authors.forename: Hermann
authors.initials: H
authors.lastname: Steinkamp
authors.forename: Andrej
authors.initials: A
authors.lastname: Schmidt
authors.forename: Horst
authors.initials: H
authors.lastname: Sievert
authors.forename: Erich
authors.initials: E
authors.lastname: Minar
authors.forename: Marc
authors.initials: M
authors.lastname: Bosiers
authors.forename: Patrick
authors.initials: P
authors.lastname: Peeters
authors.forename: Jörn O
authors.initials: JO
authors.lastname: Balzer
authors.forename: Thilo
authors.initials: T
authors.lastname: Tübler
authors.forename: Christian
authors.initials: C
authors.lastname: Wissgott
authors.forename: Oscar Gerardo Carpio
authors.initials: OG
authors.lastname: Cancino
authors.forename: Uwe
authors.initials: U
authors.lastname: Schwarzwälder
authors.forename: Thomas
authors.initials: T
authors.lastname: Zeller
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D055109:Ankle Brachial Index; D001157:Arterial Occlusive Diseases / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*; D017073:Atherectomy / Q000379:methods*; D001783:Blood Flow Velocity; D005260:Female; D005263:Femoral Artery / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011150:Popliteal Artery / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*; D012189:Retrospective Studies; D013997:Time Factors; D016896:Treatment Outcome; D018616:Ultrasonography, Doppler, Duplex