title: Novel nephrotoxins.
abstract: Drug and xenobiotic toxicity is an important cause of kidney injury, especially in vulnerable patients. Nephrotoxic syndromes include functional disorders; vascular injury, such as thrombotic microangiopathy; glomerular injury resulting in nephrotic syndrome or glomerulonephritis; acute tubular necrosis; acute interstitial nephritis; and crystalopathy/nephrolithiasis. Recently reported nephrotoxins are reviewed in the context of these syndromes of kidney injury.
authors.affiliation: Albert Einstein College of Medicine, USA. nharbord@bethisraelny.org
authors.forename: Nikolas
authors.initials: N
authors.lastname: Harbord
mesh_terms: D000225:Adenine / Q000009:adverse effects / Q000031:analogs & derivatives; D000438:Alcohols / Q000009:adverse effects; D020533:Angiogenesis Inhibitors / Q000009:adverse effects; D000927:Anticonvulsants / Q000009:adverse effects; D014150:Antipsychotic Agents / Q000009:adverse effects; D000069439:Dasatinib; D004164:Diphosphonates / Q000009:adverse effects; D005971:Glutamates / Q000009:adverse effects; D006147:Guanine / Q000009:adverse effects / Q000031:analogs & derivatives; D017320:HIV Protease Inhibitors / Q000009:adverse effects; D006801:Humans; D007211:Indoles / Q000009:adverse effects; D007674:Kidney Diseases / Q000139:chemically induced*; D063065:Organophosphonates / Q000009:adverse effects; D010070:Oxalates / Q000009:adverse effects; D000077268:Pamidronate; D000068437:Pemetrexed; D010630:Phenindione / Q000009:adverse effects / Q000031:analogs & derivatives; D010947:Plants, Toxic / Q000009:adverse effects; D054328:Proton Pump Inhibitors / Q000009:adverse effects; D011743:Pyrimidines / Q000009:adverse effects; D011758:Pyrroles / Q000009:adverse effects; D017367:Selective Serotonin Reuptake Inhibitors / Q000009:adverse effects; D000077210:Sunitinib; D000068698:Tenofovir; D013844:Thiazoles / Q000009:adverse effects; D014227:Triazines / Q000009:adverse effects
chemical_list: D000225:Adenine; D000438:Alcohols; D020533:Angiogenesis Inhibitors; D000927:Anticonvulsants; D014150:Antipsychotic Agents; D000069439:Dasatinib; D004164:Diphosphonates; D005971:Glutamates; D006147:Guanine; D017320:HIV Protease Inhibitors; D007211:Indoles; D063065:Organophosphonates; D010070:Oxalates; D000077268:Pamidronate; D000068437:Pemetrexed; D010630:Phenindione; D054328:Proton Pump Inhibitors; D011743:Pyrimidines; D011758:Pyrroles; D017367:Selective Serotonin Reuptake Inhibitors; D000077210:Sunitinib; D000068698:Tenofovir; D013844:Thiazoles; D014227:Triazines; C017673:fluindione; C011907:melamine