title: [Study of toxicity of denture prosthetic appliance prothyl hot on the Jurkat cell model system].
abstract: The aim of our study was the investigation of toxicity of denture prosthetic appliance Prothyl Hot on the model system of Jurkat cell culture. As a result of our study it was revealed that denture prosthetic appliance Prothyl Hot: - hadn't manifested toxic effects the viability Jurkat cells (that reviled by stability of activity of mitochondrial dehydrogenises and mean of mitochondrial membrane potential; - didn't influence on the balance of pro-and antyinflammatory cytokines, expressed by Jurkat cells; - induces intensification of oxidative metabolism in Jurkat cells, which may be considered as compensatory reaction developing in the cells.
authors.forename: Z K
authors.initials: ZK
authors.lastname: Nakudashvili
authors.forename: I A
authors.initials: IA
authors.lastname: Mgebrishvili
authors.forename: N K
authors.initials: NK
authors.lastname: Nakudashvili
authors.forename: T V
authors.initials: TV
authors.lastname: Mchedlishvili
authors.forename: T V
authors.initials: TV
authors.lastname: Sanikidze
mesh_terms: D017209:Apoptosis / Q000187:drug effects; D002374:Catalase / Q000378:metabolism; D016207:Cytokines / Q000378:metabolism; D003764:Dental Materials / Q000009:adverse effects*; D003778:Dentures / Q000009:adverse effects*; D005980:Glutathione Reductase / Q000378:metabolism; D006801:Humans; D019169:Jurkat Cells; D053078:Membrane Potential, Mitochondrial / Q000187:drug effects; D018384:Oxidative Stress; D013482:Superoxide Dismutase / Q000378:metabolism; D013601:T-Lymphocytes / Q000187:drug effects
chemical_list: D016207:Cytokines; D003764:Dental Materials; D002374:Catalase; D013482:Superoxide Dismutase; D005980:Glutathione Reductase