title: Syntheses of α-pyrones using gold-catalyzed coupling reactions.
abstract: Sequential alkyne activation of terminal alkynes and propiolic acids by gold(I) catalysts yields compounds having α-pyrone skeletons. Novel cascade reactions involving propiolic acids are reported that give rise to α-pyrones with different substitution patterns.
authors.affiliation: Howard Hughes Medical Institute, Broad Institute of Harvard and MIT, Cambridge, Massachusetts 02142, United States.
authors.forename: Tuoping
authors.initials: T
authors.lastname: Luo
authors.forename: Mingji
authors.initials: M
authors.lastname: Dai
authors.forename: Shao-Liang
authors.initials: SL
authors.lastname: Zheng
authors.forename: Stuart L
authors.initials: SL
authors.lastname: Schreiber
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D006046:Gold / Q000737:chemistry*; D015394:Molecular Structure; D011422:Propionates / Q000737:chemistry*; D011753:Pyrones / Q000138:chemical synthesis* / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000480:Alkynes; D011422:Propionates; D011753:Pyrones; D006046:Gold; C011537:propiolic acid