title: Plasmablastic lymphoma clinically presenting in the urinary tract.
abstract: Plasmablastic lymphoma is a high-grade B-cell lymphoma that poses major diagnostic problems and carries an extremely poor prognosis. This tumor was first described in the oral cavity of HIV+ patients but has since been identified in other sites and in seronegative patients. We describe 2 cases of plasmablastic lymphoma of the urinary tract that both presented with hydronephrosis. One occurred in an HIV+ patient and harbored a MYC translocation; the other, in an HIV- patient with no translocation detected.
authors.affiliation: Department of Genetics and Laboratory Medicine, Division of Clinical Pathology, University Hospital of Geneva, 1211 Geneva 4, Switzerland. jean-christophe.tille@hcuge.ch
authors.forename: Jean-Christophe
authors.initials: JC
authors.lastname: Tille
authors.forename: Marie-Françoise
authors.initials: MF
authors.lastname: Pelte
authors.forename: Julien
authors.initials: J
authors.lastname: Schwartz
authors.forename: Pierre-Yves
authors.initials: PY
authors.lastname: Dietrich
authors.forename: Thomas A
authors.initials: TA
authors.lastname: McKee
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology; D000368:Aged; D014408:Biomarkers, Tumor / Q000032:analysis; D003110:Colonic Neoplasms / Q000473:pathology; D015658:HIV Infections / Q000150:complications; D006801:Humans; D007150:Immunohistochemistry; D008223:Lymphoma / Q000150:complications / Q000378:metabolism / Q000473:pathology*; D016483:Lymphoma, AIDS-Related / Q000235:genetics / Q000378:metabolism / Q000473:pathology; D008297:Male; D016609:Neoplasms, Second Primary / Q000473:pathology; D014571:Urologic Neoplasms / Q000150:complications / Q000378:metabolism / Q000473:pathology*
chemical_list: D014408:Biomarkers, Tumor