title: [Comparative clinical and anatomic characteristic of patients with patent foramen ovale in cryptogenic and noncryptogenic stroke].
abstract: In order to study anatomical and functional characteristics of patent foramen ovale (PFO) in patients with cryptogenic stroke and with other stroke subtypes we examined 56 stroke patients (male--35, female--21, age 46.7 +/- 16.5 years) with PFO and ischemic stroke. Diagnosis of PFO was made by transesophageal echocardiography (TEE), contrast transcranial Doppler monitoring (C-TCD), contrast transthoracic echocardiography (C-TTE). Group 1 was made up of patients with definite stroke cause (cardioembolic, lacunar, atherotrombotic) (n=40), and group 2--of patients with cryptogenic stroke (n=16). Patients in group 2 were younger than patients in group 1 (38.7 +/- 13.4 and 50.4 +/- 16.5 years, p < 0.05) and had slight neurological symptoms. These patients also more frequently had avalvular, or "window-like" anatomic types of PFO (2 [13%] and 4 [27%] patients, respectively), combination of large anatomic size (3 mm and larger) and functional level of PFO (3 degree of the right-to-left shunt by C-TCD) (p < 0.05).
authors.forename: Z A
authors.initials: ZA
authors.lastname: Suslina
authors.forename: A V
authors.initials: AV
authors.lastname: Foniakin
authors.forename: M V
authors.initials: MV
authors.lastname: Glebov
authors.forename: L A
authors.initials: LA
authors.lastname: Geraskina
authors.forename: A O
authors.initials: AO
authors.lastname: Chechetkin
authors.forename: M A
authors.initials: MA
authors.lastname: Kravchenko
mesh_terms: D000328:Adult; D000367:Age Factors; D054087:Atrial Septum / Q000473:pathology / Q000503:physiopathology; D001921:Brain / Q000098:blood supply / Q000473:pathology; D002544:Cerebral Infarction / Q000175:diagnosis / Q000209:etiology / Q000473:pathology / Q000503:physiopathology; D017548:Echocardiography, Transesophageal; D005260:Female; D054092:Foramen Ovale, Patent / Q000150:complications / Q000175:diagnosis / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D002546:Ischemic Attack, Transient / Q000175:diagnosis / Q000209:etiology / Q000473:pathology / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D055502:Secondary Prevention; D012720:Severity of Illness Index; D017585:Ultrasonography, Doppler, Transcranial