title: Ethyl-2-cyanoacrylate as a sealant after partial cecum resection in rattus norvegicus albinus.
abstract: OBJECTIVE
  To evaluate the use of ethyl-2-cyanoacrylate in the treatment of an injury caused in a partially excluded segment of the mouse gut: the cecum.
  
  
  METHODS
  We used 45 male Wistar rats, divided into three equal groups; in all there was performed a partial resection of the cecum. The groups were designated as Group 1: the lesion was treated with application of ethyl-2-cyanoacrylate, Group 2: suture and application of ethyl-2-cyanoacrylate, Group 3: purse-string suture. The animals were monitored postoperatively and half of each group was necropsied 14 days after the procedure, the remaining on the 28th. They were subjected to macroscopic evaluation, had cecal samples collected for histological examination and the findings were submitted to statistical analysis.
  
  
  RESULTS
  Weight gain after the experiment was different among groups (p=0.028). The presence of microabscesses was higher at 28 days postoperatively in group 2 when compared to group 3 (p=0.003). The collagen deposition on the 28th postoperative day was greater in group 1 (p=0.036) and intensity of inflammation at the 14th postoperative day was greater in group 1 (p=0.045). In the other parameters there was no statistical difference.
  
  
  CONCLUSIONS
  The use of ethyl-2-cyanoacrylate was effective in the treatment of cecal stump exclusion of rats as for macroscopic and microscopic findings and postoperative outcome.
authors.affiliation: Faculty of Medicine, Federal University of Uberlandia, Uberlandia, Minas Gerais, Brazil. faionadilson@yahoo.com.br
authors.forename: Adilson Gomes
authors.initials: AG
authors.lastname: Faion
authors.forename: Augusto
authors.initials: A
authors.lastname: Diogo Filho
authors.forename: Tania Machado
authors.initials: TM
authors.lastname: de Alcantara
authors.forename: Taciana Fernandes Araujo
authors.initials: TF
authors.lastname: Ferreira
mesh_terms: D000269:Adhesives; D000818:Animals; D002432:Cecum / Q000601:surgery*; D003487:Cyanoacrylates; D051381:Rats; D017208:Rats, Wistar
chemical_list: D000269:Adhesives; D003487:Cyanoacrylates; C029054:ethyl 2-cyanoacrylate