title: Neuroimaging and functional navigation as potential tools to reduce the incidence of surgical complications of lateral ventricular meningiomas.
abstract: OBJECTIVE
  Post-operative complications are common following treatment for meningiomas in the lateral ventricles because it is unavoidable to disrupt the integrity of the brain during surgery. This study discusses our experience with strategies for reducing these complications.
  
  
  METHODS
  Twenty-seven cases of lateral ventricular meningiomas treated surgically were summarized. The surgical corridors of 11 patients were selected according to the traditional anatomical markers. Navigation technologies including neuronavigation, ultrasonography, neuro-endoscopy, fMRI and intraoperative brain mapping were used in the other 16 patients. The post-operative Karnofsky Performance Status (KPS) of patients with or without navigation were compared at 1 week and 3, 6 and 12 months.
  
  
  RESULTS
  Except for one patient who died from postoperative intracerebral hemorrhage, most of the preoperative disorders improved after surgery. Although only 4 out of 27 cases suffered from permanent complications of visual field defect or epilepsy, novel postoperative complications were found in 8 of 11 patients without navigation but in only 5 of 16 patients with navigation. The post-operative KPS of patients with navigation were better than those without navigation at 1 week and 3 months after surgery.
  
  
  CONCLUSIONS
  The use of neuroimaging and functional navigation technologies may effectively lower the incidence of postoperative complications.
authors.affiliation: Department of Neurosurgery, Southwest Hospital, The Third Military Medical University, Chongqing 400038, The People's Republic of China.
authors.forename: Fei
authors.initials: F
authors.lastname: Li
authors.forename: Jiangkai
authors.initials: J
authors.lastname: Lin
authors.forename: Gang
authors.initials: G
authors.lastname: Zhu
authors.forename: Hui
authors.initials: H
authors.lastname: Meng
authors.forename: Nan
authors.initials: N
authors.lastname: Wu
authors.forename: Rong
authors.initials: R
authors.lastname: Hu
authors.forename: Hua
authors.initials: H
authors.lastname: Feng
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D015901:Angiography, Digital Subtraction; D001931:Brain Mapping; D002551:Cerebral Ventricle Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery*; D056324:Diffusion Tensor Imaging; D004724:Endoscopy / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006849:Hydrocephalus / Q000209:etiology / Q000473:pathology; D017567:Karnofsky Performance Status; D008279:Magnetic Resonance Imaging; D008297:Male; D008579:Meningioma / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery*; D008875:Middle Aged; D016343:Monitoring, Intraoperative; D038361:Neuronavigation / Q000379:methods*; D019635:Neurosurgical Procedures / Q000379:methods*; D011183:Postoperative Complications / Q000209:etiology / Q000628:therapy*; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D014463:Ultrasonography; D014839:Vomiting / Q000209:etiology; D055815:Young Adult