title: Temporal lobe epilepsy with hypothalamic hamartoma: a rare case.
abstract: Refractory gelastic seizure is one of the most common clinical manifestations in patients with hypothalamic hamartoma (HH) and HH is usually regarded as the epileptogenic focus. A young female patient with a small HH and refractory seizures is reported here. However, both the seizure semiology and results of electroencephalogram monitoring indicated the right temporal region was the epileptogenic focus. Thus a standard right anterior temporal lobectomy was performed while the hamartoma preserved. There was a marked improvement in both seizure frequency and quality of life during a 13-month follow-up. The outcome supported the concept that independent epileptogenic focus outside of the hypothalamus might occur in patients with HH.
authors.affiliation: Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing 100050, China.
authors.forename: An-Chao
authors.initials: AC
authors.lastname: Yang
authors.forename: Kai
authors.initials: K
authors.lastname: Zhang
authors.forename: Jian-Guo
authors.initials: JG
authors.lastname: Zhang
authors.forename: Huan-Guang
authors.initials: HG
authors.lastname: Liu
authors.forename: Ning
authors.initials: N
authors.lastname: Chen
authors.forename: Ming
authors.initials: M
authors.lastname: Ge
authors.forename: Qin
authors.initials: Q
authors.lastname: Bai
authors.forename: Fan-Gang
authors.initials: FG
authors.lastname: Meng
mesh_terms: D000328:Adult; D004569:Electroencephalography; D004833:Epilepsy, Temporal Lobe / Q000175:diagnosis* / Q000601:surgery; D005260:Female; D006222:Hamartoma / Q000175:diagnosis* / Q000601:surgery; D006801:Humans; D007027:Hypothalamic Diseases / Q000175:diagnosis* / Q000601:surgery