title: Effects of treadmill running on extracellular basal levels of glutamate and GABA at dentate gyrus of streptozotocin-induced diabetic rats.
abstract: BACKGROUND
  The present study evaluated the effects of treadmill running on extracellular basal levels of glutamate and GABA at dentate gyrus of streptozotocin-induced diabetic rats.
  
  
  METHODS
  After 12 weeks of diabetes induction and exercise period, extracellular levels of glutamate and GABA were investigated.
  
  
  RESULTS
  The results showed that glutamate levels were significantly decreased in diabetes-rest group comparing to the control-rest and the diabetes-exercise groups.
  
  
  CONCLUSIONS
  The findings support the possibility that treadmill running is helpful in alleviating neurotransmitter homeostasis and alterations in transmission in diabetes mellitus.
authors.affiliation: Department of Physiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
authors.forename: Parham
authors.initials: P
authors.lastname: Reisi
authors.forename: Hojjatallah
authors.initials: H
authors.lastname: Alaei
authors.forename: Shirin
authors.initials: S
authors.lastname: Babri
authors.forename: Mohammad Reza
authors.initials: MR
authors.lastname: Sharifi
authors.forename: Gisue
authors.initials: G
authors.lastname: Mohaddes
authors.forename: Elaheh
authors.initials: E
authors.lastname: Soleimannejad
authors.forename: Bahman
authors.initials: B
authors.lastname: Rashidi