title: Multifaceted roles for lipids in viral infection.
abstract: Viruses have evolved complex and dynamic interactions with their host cell. In recent years we have gained insight into the expanding roles for host lipids in the virus life cycle. In particular, viruses target lipid signaling, synthesis, and metabolism to remodel their host cells into an optimal environment for their replication. This review highlights examples from different viruses that illustrate the importance of these diverse virus-lipid interactions.
authors.affiliation: Department of Microbiology, The University of Chicago, Chicago, IL 60637, USA.
authors.forename: Nicholas S
authors.initials: NS
authors.lastname: Heaton
authors.forename: Glenn
authors.initials: G
authors.lastname: Randall
mesh_terms: D002462:Cell Membrane / Q000378:metabolism; D004705:Endocytosis; D054884:Host-Pathogen Interactions; D050356:Lipid Metabolism; D008563:Membrane Lipids / Q000378:metabolism*; D011991:Receptors, Virus / Q000378:metabolism*; D015398:Signal Transduction; D014777:Virus Diseases / Q000378:metabolism; D053586:Virus Internalization; D014779:Virus Replication; D014780:Viruses / Q000378:metabolism*
chemical_list: D008563:Membrane Lipids; D011991:Receptors, Virus