title: Hippocampal T2 abnormalities in healthy adults.
abstract: We compared hippocampal abnormalities in 42 healthy adults identified by voxel-based relaxometry (VBR) and by visual inspection. Hippocampal abnormalities were seen in 8 (19.0%) and 10 (23.8%) of subjects by VBR and visual inspection, respectively (p>0.05). Notably, 50% of the abnormalities seen by visual inspection were likely false positive. This suggests that VBR is a more specific measure and should be considered in subjects with questionable hippocampal abnormalities.
authors.affiliation: Department of Electrical and Computer Engineering, University of Calgary, Alberta, Canada.
authors.forename: Imran
authors.initials: I
authors.lastname: Sumar
authors.forename: Robert K
authors.initials: RK
authors.lastname: Kosior
authors.forename: Richard
authors.initials: R
authors.lastname: Frayne
authors.forename: Paolo
authors.initials: P
authors.lastname: Federico
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001931:Brain Mapping; D005260:Female; D006624:Hippocampus / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D055815:Young Adult