title: A dynamic model to calculate cadmium concentrations in bovine tissues from basic soil characteristics.
abstract: A chain model was developed to calculate the flow of cadmium from soil, drinking water and feed towards bovine tissues. The data used for model development were tissue Cd concentrations of 57 bovines and Cd concentrations in soil, feed and drinking water, sampled at the farms were the bovines were reared. Validation of the model occurred with a second set of measured tissue Cd concentrations of 93 bovines of which age and farm location were known. The exposure part of the chain model consists of two parts: (1) a soil-plant transfer model, deriving cadmium concentrations in feed from basic soil characteristics (pH and organic matter content) and soil Cd concentrations, and (2) bovine intake calculations, based on typical feed and water consumption patterns for cattle and Cd concentrations in feed and drinking water. The output of the exposure model is an animal-specific average daily Cd intake, which is then taken forward to a kinetic uptake model in which time-dependent Cd concentrations in bovine tissues are calculated. The chain model was able to account for 65%, 42% and 32% of the variation in observed kidney, liver and meat Cd concentrations in the validation study.
authors.affiliation: Veterinary and Agrochemical Research Centre (CODA-CERVA), Chemical Safety of the Food Chain, Leuvensesteenweg 17, Tervuren, Belgium. nadia.waegeneers@var.fgov.be
authors.forename: Nadia
authors.initials: N
authors.lastname: Waegeneers
authors.forename: Ann
authors.initials: A
authors.lastname: Ruttens
authors.forename: Ludwig
authors.initials: L
authors.lastname: De Temmerman
mesh_terms: D000821:Animal Feed / Q000032:analysis; D000818:Animals; D002104:Cadmium / Q000032:analysis / Q000378:metabolism*; D002417:Cattle; D004781:Environmental Exposure / Q000032:analysis / Q000706:statistics & numerical data*; D008954:Models, Biological; D008956:Models, Chemical; D012987:Soil / Q000737:chemistry*; D012989:Soil Pollutants / Q000032:analysis / Q000378:metabolism*; D014874:Water Pollutants, Chemical / Q000032:analysis / Q000378:metabolism*; D014881:Water Supply / Q000032:analysis
chemical_list: D012987:Soil; D012989:Soil Pollutants; D014874:Water Pollutants, Chemical; D002104:Cadmium