title: A chemoenzymatic synthesis of 5a-carba-α-D-mannose-6-phosphate.
abstract: An efficient chemical synthesis of 5a-carba-α-D-mannose and its enzymatic elaboration to 5a-carba-α-D-mannose-6-phosphate, using yeast hexokinase, is described.
authors.affiliation: School of Chemistry and Chemical Engineering, David Kerr Building, Queen's University Belfast, Stranmillis Rd, Belfast BT9 5DG, United Kingdom.
authors.forename: Paula M
authors.initials: PM
authors.lastname: Williams
authors.forename: Gary N
authors.initials: GN
authors.lastname: Sheldrake
authors.forename: Simon J F
authors.initials: SJ
authors.lastname: Macdonald
authors.forename: Chris J
authors.initials: CJ
authors.lastname: Hamilton
mesh_terms: D006593:Hexokinase / Q000737:chemistry*; D008360:Mannosephosphates / Q000138:chemical synthesis* / Q000737:chemistry; D008956:Models, Chemical; D012441:Saccharomyces cerevisiae / Q000201:enzymology*; D014312:Trisaccharides / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D008360:Mannosephosphates; D014312:Trisaccharides; C076456:5a-carba-2-O-mannopyranosylmannopyranose; C027693:mannose-6-phosphate; D006593:Hexokinase