title: Outcomes following admission to intensive care for asthma.
abstract: OBJECTIVE
  Acute severe asthma in children is a common cause of admission to intensive care units (ICU), but there are few reports on long-term outcomes. This study describes outcomes for children with asthma admitted to an ICU.
  
  
  METHODS
  All children with asthma aged 2-18 years admitted to the ICU at the Royal Children's Hospital Melbourne between 1990 and 2004 were eligible for the study. Data were collected by reviewing medical records and through telephone interviews.
  
  
  RESULTS
  Complete data were obtained for 410 (61%) of 684 eligible patients. The mean duration of follow-up was 10.3±4.6 years. After the index admission, 67% were readmitted to hospital for asthma and 17% to the ICU. Eighty-eight per cent continued to have asthma: 46% had episodic asthma and 42% persistent asthma. Twelve patients (1.8%) subsequently died from asthma. Five per cent of those who required ventilation at their index admission died within 10 years. Risk factors for ICU readmission were admission for asthma in the preceding year (AOR 4.7; 95% CI 2.4 to 9.3) and ventilation at admission (AOR 2.4; 95% CI 1.0 to 5.3). Risk factors for subsequent mortality were multiple ICU admissions (AOR 5.0; 95% CI 1.3 to 19), persistent asthma (AOR 5.8; 95% CI 1.2 to 28.5) and ventilation at admission (AOR 4.5; 95% CI 1.3 to 15.7).
  
  
  CONCLUSIONS
  Admission to the ICU for asthma is a predictor of hospital readmission. Those with persistent asthma or requiring ventilation are at significant risk of mortality in subsequent years and require close follow-up.
authors.affiliation: Department of Respiratory Medicine, Royal Children's Hospital Melbourne, Flemington Rd, Parkville, Victoria 3052, Australia. rina_triasih@yahoo.com
authors.forename: Rina
authors.initials: R
authors.lastname: Triasih
authors.forename: Trevor
authors.initials: T
authors.lastname: Duke
authors.forename: Colin F
authors.initials: CF
authors.lastname: Robertson
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D001249:Asthma / Q000401:mortality / Q000628:therapy*; D002648:Child; D002675:Child, Preschool; D003422:Critical Care / Q000379:methods*; D004812:Epidemiologic Methods; D005260:Female; D006760:Hospitalization; D006801:Humans; D007902:Length of Stay / Q000706:statistics & numerical data; D008297:Male; D010359:Patient Readmission / Q000706:statistics & numerical data; D011379:Prognosis; D012121:Respiration, Artificial; D014739:Victoria / Q000453:epidemiology