title: Blood purification in toxicology: nephrology's ugly duckling.
abstract: Contrary to popular opinion, application of extracorporeal therapies for poisonings predates their use for ESRD. Despite this observation, the science of blood purification in toxicology remains desperately stagnant today. In fact, much of our current knowledge is derived from George Schreiner's 1958 review. Original publications are almost exclusively composed of case reports and case series, from which good inference is impossible. Until randomized controlled trials become available, the medical community would be well served by a group mandated to systematically review available literature, extract relevant information, provide recommendations based on current evidence, and propose research initiatives. The EXtracorporeal TReatments In Poisoning workgroup, formed by several international experts in different medical fields and represented by over 20 societies, now has this mission.
authors.affiliation: Department of Nephrology, Verdun Hospital, University of Montreal, Quebec, Canada. marcghannoum@gmail.com
authors.forename: Marc
authors.initials: M
authors.lastname: Ghannoum
authors.forename: Thomas D
authors.initials: TD
authors.lastname: Nolin
authors.forename: Valery
authors.initials: V
authors.lastname: Lavergne
authors.forename: Robert S
authors.initials: RS
authors.lastname: Hoffman
mesh_terms: D049672:History, 19th Century; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D011041:Poisoning / Q000266:history* / Q000628:therapy; D006435:Renal Dialysis / Q000266:history* / Q000295:instrumentation