title: Endoscopic submucosal dissection combined with the placement of biodegradable stents for recurrent esophageal cancer after chemoradiotherapy.
abstract: We report a case of a patient with esophageal squamous cell carcinoma who presented with obstruction of the esophagus. On endoscopy, a central ulcerating lesion was found spreading to the anterior wall of the middle esophagus. Four courses of chemoradiation therapy successfully produced a complete response for 3 years. A recurrence occurred which consisted of a morphologically flat lesion that occupied the entire circumference of the esophagus. Endoscopic submucosal dissection removed all lesions en bloc. To prevent a post-procedure mucosal defect of the circumference of the esophagus, biodegradable poly-l-lactic acid monofilaments esophageal stents were placed on the same day. One month later, the patient reported a feeling of obstruction. An endoscopic examination revealed food stuck in the stents, this was removed, and balloon dilatation provided good passage which has been maintained for 7 months.
authors.affiliation: Division of Digestive Endoscopy, Department of Medicine, Shiga University of Medical Science, Seta-Tukinowa, Otsu, 520-2192, Japan.
authors.forename: Yosuke
authors.initials: Y
authors.lastname: Mochizuki
authors.forename: Yasuharu
authors.initials: Y
authors.lastname: Saito
authors.forename: Toyohiko
authors.initials: T
authors.lastname: Tanaka
authors.forename: Norihisa
authors.initials: N
authors.lastname: Nitta
authors.forename: Hirokazu
authors.initials: H
authors.lastname: Yamada
authors.forename: Tomoyuki
authors.initials: T
authors.lastname: Tsujikawa
authors.forename: Kiyoshi
authors.initials: K
authors.lastname: Murata
authors.forename: Yoshihide
authors.initials: Y
authors.lastname: Fujiyama
authors.forename: Akira
authors.initials: A
authors.lastname: Andoh
mesh_terms: D020341:Absorbable Implants; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000601:surgery*; D059248:Chemoradiotherapy; D004938:Esophageal Neoplasms / Q000473:pathology / Q000601:surgery*; D004940:Esophageal Stenosis / Q000209:etiology / Q000601:surgery; D004945:Esophagoscopy / Q000295:instrumentation* / Q000379:methods; D006801:Humans; D019344:Lactic Acid; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000473:pathology / Q000601:surgery*; D011091:Polyesters; D011108:Polymers; D015607:Stents
chemical_list: D011091:Polyesters; D011108:Polymers; D019344:Lactic Acid; C033616:poly(lactide)