title: Mechanotransduction: getting morphogenesis down pat.
abstract: Embryonic morphogenesis requires the coordination of forces across multiple tissues and their associated extracellular matrices. A new study reports a mechanical feedback loop in the Caenorhabditis elegans embryo between muscle and epidermis that may provide a model for understanding how tissues coordinate morphogenetic events in the embryo.
authors.affiliation: Department of Zoology, University of Wisconsin, Madison, WI 53706, USA. jdhardin@wisc.edu
authors.forename: Jeff
authors.initials: J
authors.lastname: Hardin
mesh_terms: D022005:Adherens Junctions / Q000378:metabolism; D000818:Animals; D015820:Cadherins / Q000378:metabolism; D017173:Caenorhabditis elegans / Q000196:embryology*; D029742:Caenorhabditis elegans Proteins / Q000378:metabolism; D051177:Catenins / Q000378:metabolism; D004817:Epidermis / Q000196:embryology* / Q000378:metabolism; D005109:Extracellular Matrix / Q000378:metabolism*; D040542:Mechanotransduction, Cellular / Q000502:physiology*; D008954:Models, Biological; D009024:Morphogenesis / Q000502:physiology*; D018482:Muscle, Skeletal / Q000196:embryology* / Q000378:metabolism; D054462:p21-Activated Kinases / Q000378:metabolism
chemical_list: D015820:Cadherins; D029742:Caenorhabditis elegans Proteins; D051177:Catenins; C101878:pak-1 protein, C elegans; D054462:p21-Activated Kinases