title: Two cases of cerebral embolism caused by apical thrombi in midventricular obstructive cardiomyopathy.
abstract: Midventricular obstructive hypertrophic cardiomyopathy (MOHC) is a rare form of cardiomyopathy that was demonstrated to have caused embolic stroke in two patients. In both cases, the embolic sources of stroke were thrombi in an apical aneurysm caused by turbulent stasis of blood flow and subsequent injury of myocardial endocardium. Even without atrial fibrillation, apical aneurysm can induce emboligenic stroke in MOHC.
authors.affiliation: Department of Clinical Neuroscience and Therapeutics, Hiroshima University, Graduate School of Biomedical Sciences, Japan. itakeda@hiroshima-u.ac.jp
authors.forename: Ikuko
authors.initials: I
authors.lastname: Takeda
authors.forename: Mayu
authors.initials: M
authors.lastname: Sekine
authors.forename: Hayato
authors.initials: H
authors.lastname: Matsushima
authors.forename: Naohisa
authors.initials: N
authors.lastname: Hosomi
authors.forename: Takeshi
authors.initials: T
authors.lastname: Nakamura
authors.forename: Toshiho
authors.initials: T
authors.lastname: Ohtsuki
authors.forename: Takemori
authors.initials: T
authors.lastname: Yamawaki
authors.forename: Masayasu
authors.initials: M
authors.lastname: Matsumoto
mesh_terms: D000328:Adult; D000368:Aged; D002312:Cardiomyopathy, Hypertrophic / Q000150:complications* / Q000175:diagnosis; D003323:Coronary Aneurysm / Q000150:complications; D004452:Echocardiography; D005260:Female; D006801:Humans; D020766:Intracranial Embolism / Q000175:diagnosis / Q000209:etiology*; D008279:Magnetic Resonance Imaging; D008297:Male