title: "Very Late" isolated para-aortic nodal recurrence of carcinoma cervix mimicking radiation-induced sarcoma.
abstract: Only a minority of the patients who develop recurrence after definitive treatment for cervical cancer are detected after 5 years (late recurrence); the numbers are lesser still after 10 years (very late recurrence). Among the infrequent cases that do develop "late" and "very late" recurrence, the commonest site is the pelvis. We report an unusually rare recurrence of treated cervical cancer confined to the para-aortic nodal group after a protracted disease-free interval of 13 years. On the basis of the long disease-free interval, location of the mass at the periphery of the radiation field, and aggressive imaging appearance, a diagnosis of radiation-induced sarcoma was considered. However, the final diagnosis of isolated para-aortic nodal recurrence of cervical cancer was rendered based on the histopathological and immunohistochemistry findings, supported by the absence of disease elsewhere on whole-body imaging.
authors.affiliation: Bioimaging Unit, Tata Memorial Hospital, Parel, Mumbai 400 012, India.
authors.forename: Sumeet G
authors.initials: SG
authors.lastname: Dua
authors.forename: Nilendu C
authors.initials: NC
authors.lastname: Purandare
authors.forename: Siddhartha
authors.initials: S
authors.lastname: Laskar
authors.forename: Sneha
authors.initials: S
authors.lastname: Shah
authors.forename: Kedar K
authors.initials: KK
authors.lastname: Deodhar
authors.forename: V
authors.initials: V
authors.lastname: Rangarajan
mesh_terms: D000328:Adult; D001011:Aorta / Q000473:pathology*; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology*; D008207:Lymphatic Metastasis; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis*; D009381:Neoplasms, Radiation-Induced / Q000175:diagnosis*; D012509:Sarcoma / Q000175:diagnosis*; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis*