title: The perils of medical tourism: NDM-1-positive Escherichia coli causing febrile neutropenia in a medical tourist.
abstract: NDM-1 is a new metallo-beta-lactamase that readily hydrolyses carbapenems, penicillins and cephalosporins. Its rising incidence has been reported in many countries around the world, with many cases linked to a possible origin from the Indian subcontinent. Due to the lack of effective antibiotic regimes to treat these infections, the increased prevalence of NDM-1 is alarming. We describe a case of NDM-1 infection in an immunocompromised foreign patient, and discuss its implications.
authors.affiliation: Department of Haematology-Oncology, National Univeristy Hospital, 1E Lower Kent Ridge Road, NUHS Tower Block Level 7, Singapore 119228. esther.hl.chan@gmail.com
authors.forename: H L E
authors.initials: HL
authors.lastname: Chan
authors.forename: L M
authors.initials: LM
authors.lastname: Poon
authors.forename: S G
authors.initials: SG
authors.lastname: Chan
authors.forename: J W P
authors.initials: JW
authors.lastname: Teo
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D024881:Drug Resistance, Bacterial; D018432:Drug Resistance, Multiple; D004926:Escherichia coli / Q000378:metabolism*; D005260:Female; D005334:Fever / Q000175:diagnosis* / Q000209:etiology; D006801:Humans; D016867:Immunocompromised Host; D015994:Incidence; D057193:Medical Tourism; D008875:Middle Aged; D009503:Neutropenia / Q000175:diagnosis* / Q000209:etiology; D016896:Treatment Outcome; D001618:beta-Lactamases / Q000096:biosynthesis* / Q000378:metabolism
chemical_list: D000900:Anti-Bacterial Agents; D001618:beta-Lactamases; C552864:beta-lactamase NDM-1