title: An aerobic [2 + 2 + 2] cyclization via chloropalladation: from 1,6-diynes and acrylates to substituted aromatic carbocycles.
abstract: A Pd-catalyzed aerobic [2 + 2 + 2] cyclization of 1,6-diynes and acrylates proceeding through a chloropalladation process has been developed. Polysubstituted five-membered aromatic carbocycles/heterocycles were obtained in good to excellent yields. The results of the mechanistic study are consistent with the proposed reaction mechanism.
authors.affiliation: School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510640, P R China.
authors.forename: Peng
authors.initials: P
authors.lastname: Zhou
authors.forename: Meifang
authors.initials: M
authors.lastname: Zheng
authors.forename: Huanfeng
authors.initials: H
authors.lastname: Jiang
authors.forename: Xianwei
authors.initials: X
authors.lastname: Li
authors.forename: Chaorong
authors.initials: C
authors.lastname: Qi
mesh_terms: D000179:Acrylates / Q000737:chemistry*; D000332:Aerobiosis; D003500:Cyclization; D053280:Diynes / Q000737:chemistry*; D006571:Heterocyclic Compounds / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*
chemical_list: D000179:Acrylates; D053280:Diynes; D006571:Heterocyclic Compounds; D010165:Palladium