title: Managing diffuse oesophageal spasm.
abstract: Non-cardiac chest pain is common,1 affecting around 25% of the population during their lifetime and accounting for about 2-5% of presentations to hospital accident and emergency departments.2 Around 10% of patients presenting with such pain, and up to 13% of those presenting with functional dysphagia, have diffuse oesophageal spasm (DOS), an oesophageal motility disorder.3,4 DOS is often recognised and treated only after patients have attended hospital emergency departments and specialist clinics for years, because of the non-specific nature of their symptoms and difficulty in diagnosis (features common to motility disorders).5 Here we discuss the diagnosis and further management of patients with DOS.
mesh_terms: D000928:Antidepressive Agents / Q000627:therapeutic use; D019274:Botulinum Toxins, Type A / Q000627:therapeutic use; D003376:Counseling; D015155:Esophageal Spasm, Diffuse / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy*; D006801:Humans; D008019:Life Style; D009465:Neuromuscular Agents / Q000627:therapeutic use; D010276:Parasympatholytics / Q000627:therapeutic use
chemical_list: D000928:Antidepressive Agents; D009465:Neuromuscular Agents; D010276:Parasympatholytics; D019274:Botulinum Toxins, Type A