title: Draft genome sequence of the marine bacterium Streptomyces griseoaurantiacus M045, which produces novel manumycin-type antibiotics with a pABA core component.
abstract: Streptomyces griseoaurantiacus M045, isolated from marine sediment, produces manumycin and chinikomycin antibiotics. Here we present a high-quality draft genome sequence of S. griseoaurantiacus M045, the first marine Streptomyces species to be sequenced and annotated. The genome encodes several gene clusters for biosynthesis of secondary metabolites and has provided insight into genomic islands linking secondary metabolism to functional adaptation in marine S. griseoaurantiacus M045.
authors.affiliation: Nanjing Agricultural University, Nanjing 210095, China.
authors.forename: Fuchao
authors.initials: F
authors.lastname: Li
authors.forename: Peng
authors.initials: P
authors.lastname: Jiang
authors.forename: Huajun
authors.initials: H
authors.lastname: Zheng
authors.forename: Shengyue
authors.initials: S
authors.lastname: Wang
authors.forename: Guoping
authors.initials: G
authors.lastname: Zhao
authors.forename: Song
authors.initials: S
authors.lastname: Qin
authors.forename: Zhaopu
authors.initials: Z
authors.lastname: Liu
mesh_terms: D000900:Anti-Bacterial Agents / Q000096:biosynthesis; D053898:Biosynthetic Pathways / Q000235:genetics; D004269:DNA, Bacterial / Q000737:chemistry* / Q000235:genetics*; D016680:Genome, Bacterial; D044404:Genomic Islands; D019015:Geologic Sediments / Q000382:microbiology; D008969:Molecular Sequence Data; D005810:Multigene Family; D011090:Polyenes / Q000378:metabolism; D053284:Polyunsaturated Alkamides / Q000378:metabolism; D017422:Sequence Analysis, DNA; D013302:Streptomyces / Q000235:genetics* / Q000302:isolation & purification / Q000378:metabolism
chemical_list: D000900:Anti-Bacterial Agents; D004269:DNA, Bacterial; D011090:Polyenes; D053284:Polyunsaturated Alkamides; C499737:chinikomycin A; C499738:chinikomycin B; C054474:manumycin