title: Right ventricular endocarditis in a pregnant woman with a restrictive ventricular septal defect.
abstract: A 22-year-old woman with a restrictive unoperated perimembranous ventricular septal defect was diagnosed with staphylococcal endocarditis during her 14th week of pregnancy. Echocardiography revealed a long, thin, and mobile vegetation along the right ventricular free wall that increased to 8 cm in length, with systolic protrusion across the pulmonary valve. The vegetation subsequently embolized, resulting in a pulmonary abscess. She responded favorably to intravenous antibiotic therapy maintained for a total of 6 weeks, with resolution of the intracardiac mass and pulmonary abscess. The remaining peripartum and postpartum course was relatively unremarkable. Percutaneous closure of the ventricular septal defect was successfully performed postpartum.
authors.affiliation: Adult Congenital Heart Disease Centre, Montreal Heart Institute Department of Obstetrics & Gynaecology, Sainte Justine Hospital, Université de Montréal, 5000 Belanger StreetEast, Montreal, QC, Canada. l.legloan@voila.fr
authors.forename: Laurianne
authors.initials: L
authors.lastname: Le Gloan
authors.forename: Line
authors.initials: L
authors.lastname: Leduc
authors.forename: Eileen
authors.initials: E
authors.lastname: O'Meara
authors.forename: Paul
authors.initials: P
authors.lastname: Khairy
authors.forename: Annie
authors.initials: A
authors.lastname: Dore
mesh_terms: D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D006328:Cardiac Catheterization; D004697:Endocarditis, Bacterial / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000382:microbiology*; D005260:Female; D006345:Heart Septal Defects, Ventricular / Q000150:complications* / Q000628:therapy; D006352:Heart Ventricles / Q000382:microbiology; D006801:Humans; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D050498:Live Birth; D008169:Lung Abscess / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000382:microbiology*; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000382:microbiology*; D011251:Pregnancy Complications, Infectious / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000382:microbiology*; D013203:Staphylococcal Infections / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000382:microbiology*; D013211:Staphylococcus aureus / Q000302:isolation & purification*; D016896:Treatment Outcome; D014463:Ultrasonography; D055815:Young Adult
chemical_list: D000900:Anti-Bacterial Agents