title: Corneal power after DSAEK using microkeratome-prepared tissues.
abstract: OBJECTIVE
  To investigate changes of corneal power after descemet stripping automated endothelial keratoplasty (DSAEK).
  
  
  METHODS
  Anterior, posterior, and true-net (anterior + posterior) power of post-DSAEK and contralateral transparent corneas were measured, using the Pentacam rotating Scheimpflug camera (Oculus Wetzlar, Germany), 6 months after surgery in 23 consecutive patients who had undergone unilateral DSAEK at the same medical center. Moreover, in each cornea, Pentacam pachimetry was measured at the vertex and at 3 mm from the vertex, to calculate corneal thickness increase (CTI).
  
  
  RESULTS
  In post-DSAEK corneas, the anterior power on average decreased by -0.24 ± 0.61 diopters (D), the negative posterior power increased by -0.96 ± 0.42 D, and the true-net power decreased by -1.19 ± 0.74 D (range: +0.17 to -2.23 D). Differences vs. contralateral transparent corneas did not reach statistical significance for anterior (p = 0.09) but were significant (p < 0.001) for posterior and true-net corneal power. CTI at 3 mm from the vertex was statistically larger (p < 0.0001) in post-DSAEK corneas (mean values 0.27 ± 0.07 vs. 0.12 ± 0.05); CTI values showed a statistically significant (p < 0.05) correlation with negative posterior corneal power values in post-DSAEK (r = -0.55) and in contralateral corneas (r = -0.67).
  
  
  CONCLUSIONS
  In comparison with contralateral corneas, post-DSAEK corneas show a moderate reduction of the true-net corneal power measured by Pentacam. Knowledge of true-net corneal power changes might be useful in adjusting K values and calculating intraocular lens power, in eyes scheduled for DSAEK combined with intraocular lens implantation/exchange.
authors.affiliation: Department of Clinical Physiopathology, Ophthalmology Institute, University of Turin, Turin, Italy. ugo.de_sanctis@unito.it
authors.forename: Ugo
authors.initials: U
authors.lastname: de Sanctis
authors.forename: Marco
authors.initials: M
authors.lastname: Angeloni
authors.forename: Cristina
authors.initials: C
authors.lastname: Zilio
authors.forename: Diego
authors.initials: D
authors.lastname: Sacco
authors.forename: Federico
authors.initials: F
authors.lastname: Grignolo
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003315:Cornea / Q000503:physiopathology* / Q000601:surgery*; D057111:Descemet Stripping Endothelial Keratoplasty / Q000009:adverse effects*; D003941:Diagnostic Techniques, Ophthalmological / Q000295:instrumentation; D005260:Female; D006652:Histological Techniques; D006801:Humans; D008297:Male; D008875:Middle Aged; D011184:Postoperative Period; D014054:Tomography