title: Device-associated infection rates and bacterial resistance in the intensive care units of a Turkish referral hospital.
abstract: OBJECTIVE
  To determine device-associated infection (DAI) rates, and the microbiological and antibiotic resistance profiles of infecting pathogens in our hospital.
  
  
  METHODS
  Prospective surveillance of healthcare-associated infections was performed from January 2007 to March 2010 in 4 different intensive care units (ICUs) of SB Diskapi Yildirim Beyazit Training and Research Hospital, Ankara, Turkey.
  
  
  RESULTS
  During the study period, 6,005 patients were followed-up in ICUs for a total of 46,355 patient-days. The total number of DAIs was 969. Catheter-associated urinary tract infection (CAUTI) was the most common DAI (55.3% of DAIs; 11.9 cases per 1000 catheter-days), followed by ventilator-associated pneumonia (VAP) (38.9% of DAIs; 21.2 cases per 1000 ventilator-days), and central line-associated blood stream infection (CLABSI) (5.8% of DAIs; 2.8 cases per 1000 central line-days). The most frequently isolated pathogens in patients with VAP were Acinetobacter species (24.5%) and Escherichia coli in CAUTI (24.2%). Coagulase negative Staphylococci and Candida species were the leading pathogens in patients with CLABSI.
  
  
  CONCLUSIONS
  We observed considerably high rates of VAP and CAUTI and a high rate of CLABSI in our ICUs when compared with the National Healthcare Safety Network data. These findings emphasize the need to improve infection control practices and management of invasive device use in our hospital.
authors.affiliation: Department of Infectious Diseases and Clinical Microbiology, SB Diskapi Yildirim Beyazit Training and Research Hospital, PO Box 34 Asagi Ayranci, Ankara 06541, Turkey. ediztutuncu@gmail.com
authors.forename: Emin E
authors.initials: EE
authors.lastname: Tutuncu
authors.forename: Yunus
authors.initials: Y
authors.lastname: Gurbuz
authors.forename: Irfan
authors.initials: I
authors.lastname: Sencan
authors.forename: Baris
authors.initials: B
authors.lastname: Ozturk
authors.forename: Gonul C
authors.initials: GC
authors.lastname: Senturk
authors.forename: Aysegul U
authors.initials: AU
authors.lastname: Kilic
mesh_terms: D016470:Bacteremia / Q000453:epidemiology / Q000382:microbiology; D055499:Catheter-Related Infections / Q000453:epidemiology / Q000382:microbiology; D003428:Cross Infection / Q000453:epidemiology* / Q000382:microbiology; D024881:Drug Resistance, Bacterial; D006801:Humans; D007362:Intensive Care Units; D053717:Pneumonia, Ventilator-Associated / Q000453:epidemiology / Q000382:microbiology; D011159:Population Surveillance; D011446:Prospective Studies; D014421:Turkey