title: Infant mortality rates regressed against number of vaccine doses routinely given: is there a biochemical or synergistic toxicity?
abstract: The infant mortality rate (IMR) is one of the most important indicators of the socio-economic well-being and public health conditions of a country. The US childhood immunization schedule specifies 26 vaccine doses for infants aged less than 1 year--the most in the world--yet 33 nations have lower IMRs. Using linear regression, the immunization schedules of these 34 nations were examined and a correlation coefficient of r = 0.70 (p < 0.0001) was found between IMRs and the number of vaccine doses routinely given to infants. Nations were also grouped into five different vaccine dose ranges: 12-14, 15-17, 18-20, 21-23, and 24-26. The mean IMRs of all nations within each group were then calculated. Linear regression analysis of unweighted mean IMRs showed a high statistically significant correlation between increasing number of vaccine doses and increasing infant mortality rates, with r = 0.992 (p = 0.0009). Using the Tukey-Kramer test, statistically significant differences in mean IMRs were found between nations giving 12-14 vaccine doses and those giving 21-23, and 24-26 doses. A closer inspection of correlations between vaccine doses, biochemical or synergistic toxicity, and IMRs is essential.
authors.affiliation: Think Twice Global Vaccine Institute, USA. neilzmiller@gmail.com [corrected]
authors.forename: Neil Z
authors.initials: NZ
authors.lastname: Miller
authors.forename: Gary S
authors.initials: GS
authors.lastname: Goldman
mesh_terms: D001669:Biochemical Phenomena; D004357:Drug Synergism; D014943:Global Health; D006801:Humans; D007114:Immunization / Q000706:statistics & numerical data*; D007115:Immunization Schedule; D007223:Infant; D007226:Infant Mortality / Q000639:trends*; D016014:Linear Models; D014612:Vaccines / Q000737:chemistry / Q000633:toxicity*
chemical_list: D014612:Vaccines