title: [Prevention of mitochondrial diseases: a hope through assisted reproductive technologies].
abstract: Mitochondrial diseases are a heterogenic and poorly studied group of diseases, considered serious in most cases and currently without treatment. Although assisted reproduction proposed strategies to prevent them, such as pre-implantation genetic diagnosis, these techniques are not sufficiently successful. However, the recent publication of two assistedreproduction techniques – meiotic spindle transfer in nonhuman primates and pronuclear transfer in humans – generate a clear ray of hope for the prevention of these diseases. This review analyzes the characteristics and meaning of these new findings and their future clinical implications.
authors.affiliation: Facultad de Medicina, Universidad Autónoma de Yucatán, Mérida, Yuc. rpina.a@hotmail.com
authors.forename: Raúl Eduardo
authors.initials: RE
authors.lastname: Piña-Aguilar
mesh_terms: D006801:Humans; D028361:Mitochondrial Diseases / Q000235:genetics / Q000517:prevention & control*; D053652:Nuclear Transfer Techniques; D027724:Reproductive Techniques, Assisted