title: [Studies of burnt folium nelumbinis in anastalsis and processing].
abstract: OBJECTIVE
  To research the hemostatic components of burnt Folium Nelumbinis and select a better method of processing.
  
  
  METHODS
  The anastalsis of medicinal materials between various collection period and the main astrictive parts of burnt Folium Nelumbinis were reviewed by slide method. The powder was observed by microscopic identification. The content of alkaloid was assayed by HPLC. The new method of processing was selected by the orthogonal experiment.
  
  
  RESULTS
  The lotus leaf in terminal growth can significantly shorten the clotting time and its carbon is more significant which is consistent with other analysis results. The n-butanol part from burnt Folium Nelumbinis can significantly shorten the clotting time. The optimum processing of the new method is 140 degrees C, 20 min and its product meets relevant regulations.
  
  
  CONCLUSIONS
  In preliminary view, n-butanol part from burnt Folium Nelumbinis is the main astrictive site. It is reasonable to make the lotus leaf in terminal growth into carbon. It is feasible to carbonize by muffle furnace.
authors.affiliation: School of Pharmacy, Medical College of Soochow University, Suzhou 215123, China. jxliaoli@126.com
authors.forename: Li
authors.initials: L
authors.lastname: Liao
authors.forename: Zhan
authors.initials: Z
authors.lastname: Shu
authors.forename: Xiao-Ran
authors.initials: XR
authors.lastname: Li
authors.forename: Shi-Lin
authors.initials: SL
authors.lastname: Yang
authors.forename: Li-Li
authors.initials: LL
authors.lastname: Hao
mesh_terms: D000284:Administration, Oral; D000470:Alkaloids / Q000032:analysis; D000818:Animals; D001780:Blood Coagulation Tests; D002851:Chromatography, High Pressure Liquid; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D005260:Female; D006490:Hemostatics / Q000008:administration & dosage / Q000494:pharmacology*; D008297:Male; D051379:Mice; D031653:Nelumbo / Q000737:chemistry*; D018515:Plant Leaves / Q000737:chemistry; D012621:Seasons; D013678:Technology, Pharmaceutical / Q000379:methods*
chemical_list: D000470:Alkaloids; D004365:Drugs, Chinese Herbal; D006490:Hemostatics