title: Incidence of deep vein thrombosis and pulmonary embolus following periacetabular osteotomy.
abstract: BACKGROUND
  Venous thromboembolism, a known complication of orthopaedic procedures, is thought to be more prevalent following hip surgery. Venous thromboembolism risk assessment and appropriate prophylaxis according to the American College of Chest Physicians guidelines has become the standard of care. However, it is accepted that venous thromboembolism prophylaxis is associated with potential adverse sequelae including hematoma, wound drainage, and infection. Little is known regarding the incidence of venous thromboembolism following periacetabular osteotomy and the necessity for and method of routine prophylaxis.
  
  
  METHODS
  A total of 1067 periacetabular osteotomies performed at six North American centers utilizing different methods of prophylaxis against venous thromboembolism were analyzed for type of prophylaxis and incidence of clinically symptomatic venous thromboembolism.
  
  
  RESULTS
  There were four cases of pulmonary embolus and seven cases of deep vein thrombosis. There were no reported deaths. The crude incidence of clinically symptomatic venous thromboembolism was 9.4 per 1000 procedures.
  
  
  CONCLUSIONS
  The risk from chemoprophylaxis and the development of hematoma may be greater than the risk of clinically important venous thromboembolism in patients undergoing periacetabular osteotomy.
authors.affiliation: Department of Orthopaedic Surgery, William Beaumont Hospital, 30575 Woodward Avenue, Royal Oak, MI 48073, USA. zaltzira@gmail.com
authors.forename: Ira
authors.initials: I
authors.lastname: Zaltz
authors.forename: Paul
authors.initials: P
authors.lastname: Beaulé
authors.forename: John
authors.initials: J
authors.lastname: Clohisy
authors.forename: Perry
authors.initials: P
authors.lastname: Schoenecker
authors.forename: Daniel
authors.initials: D
authors.lastname: Sucato
authors.forename: David
authors.initials: D
authors.lastname: Podeszwa
authors.forename: Rafael
authors.initials: R
authors.lastname: Sierra
authors.forename: Robert
authors.initials: R
authors.lastname: Trousdale
authors.forename: Young-Jo
authors.initials: YJ
authors.lastname: Kim
authors.forename: Michael B
authors.initials: MB
authors.lastname: Millis
mesh_terms: D000077:Acetabulum / Q000601:surgery*; D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D009656:North America / Q000453:epidemiology; D010027:Osteotomy / Q000009:adverse effects*; D011655:Pulmonary Embolism / Q000453:epidemiology / Q000209:etiology* / Q000517:prevention & control; D012189:Retrospective Studies; D012307:Risk Factors; D020246:Venous Thrombosis / Q000453:epidemiology / Q000209:etiology* / Q000517:prevention & control