title: Impact of diabetes and smoking epidemic in the Middle East on the presentation with acute coronary syndrome in very young patients.
abstract: We describe the baseline characteristics, management, and outcomes of acute coronary syndrome (ACS) in patients of age ≤ 40 in the Gulf region of the Middle East. We studied 8176 hospitalized patients (≤ 40 years) with ACS. Ten percent (805) of the recruited patients were ≤ 40 years. The mean age was 37 years and 89% were males. The prevalence of smoking and diabetes in the young patients was high (58% and 21%, respectively). The most common ACS was ST elevation myocardial infarction. Younger patients were more aggressively treated with more frequent use of glycoprotein inhibitors, thrombolytics, and primary percutaneous coronary intervention. They had less in-hospital heart failure, left ventricular dysfunction, shock, stroke, and low rate of in-hospital mortality (1%). Measures to combat the rising prevalence of diabetes and smoking are needed.
authors.affiliation: 1Department of Medicine, Faculty of Medicine, Kuwait University, Safat, Kuwait.
authors.forename: Muath
authors.initials: M
authors.lastname: Alanbaei
authors.forename: Mohammad
authors.initials: M
authors.lastname: Zubaid
authors.forename: Mouaz H
authors.initials: MH
authors.lastname: Al-Mallah
authors.forename: Wafa A
authors.initials: WA
authors.lastname: Rashed
authors.forename: Abdullah
authors.initials: A
authors.lastname: Shehab
authors.forename: Jawad
authors.initials: J
authors.lastname: Al-Lawati
authors.forename: Mb
authors.initials: M
authors.lastname: Chb
authors.forename: Haitham
authors.initials: H
authors.lastname: Amin
authors.forename: Jassim
authors.initials: J
authors.lastname: Al Suwaidi
authors.forename: Rashed
authors.initials: R
authors.lastname: Al-Hamdan
authors.forename: Shahid
authors.initials: S
authors.lastname: Zubair
mesh_terms: D054058:Acute Coronary Syndrome / Q000175:diagnosis / Q000453:epidemiology* / Q000523:psychology; D000328:Adult; D000367:Age Factors; D000368:Aged; D015331:Cohort Studies; D003920:Diabetes Mellitus / Q000208:ethnology* / Q000523:psychology; D005260:Female; D006760:Hospitalization; D006801:Humans; D008297:Male; D008875:Middle Aged; D008877:Middle East; D015995:Prevalence; D012307:Risk Factors; D012907:Smoking / Q000208:ethnology*