title: Association of invasive breast carcinoma and multicentric high grade astrocytoma: a case report with a review.
abstract: Breast cancer is the most common cancer in women. Multicentric gliomas are uncommon lesions of the central nervous system (CNS) with an unprecise rate of occurrence that diffusely infiltrate large portions of the brain. High grade astrocytoma is the most agressive form of gliomas and often has a distinct neuroimaging pattern with a poor prognosis. We report a case of a 29-year-old woman patient with primary breast carcinoma and high grade astrocytoma subsequently developed. The woman was treated by mastectomy and 20 months post-diagnosis of the cancer she exhibited a transient facial paralysis. Magnetic resonance imaging (MRI) revealed two cranial masses suspicious of metastasis. A complete tumor removal from the brain was performed. On histological examination, this tumor was a high grade astrocytoma.
authors.affiliation: Department of Pathology, Shahrekord University of Medical Sciences and Health Services, Shahrekord, Iran.
authors.forename: P Hossein
authors.initials: PH
authors.lastname: Pour
authors.forename: M
authors.initials: M
authors.lastname: Forouzandeh
authors.forename: A Naderi
authors.initials: AN
authors.lastname: Beni
authors.forename: Z Naderi
authors.initials: ZN
authors.lastname: Beni
authors.forename: P
authors.initials: P
authors.lastname: Hoseinpour
mesh_terms: D000328:Adult; D001254:Astrocytoma / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D014408:Biomarkers, Tumor / Q000032:analysis; D001706:Biopsy; D001932:Brain Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D001943:Breast Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D018270:Carcinoma, Ductal, Breast / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D017024:Chemotherapy, Adjuvant; D016371:Cranial Irradiation; D003399:Craniotomy; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008279:Magnetic Resonance Imaging; D015409:Mastectomy, Radical; D009367:Neoplasm Staging; D016609:Neoplasms, Second Primary; D018714:Radiotherapy, Adjuvant; D016896:Treatment Outcome
chemical_list: D014408:Biomarkers, Tumor