title: p63 expression in randomized odontogenic cysts.
abstract: OBJECTIVE
  To find out the immunohistochemical assessment of p63 expression in odontogenic cysts based on the differences among their clinical behaviors.
  
  
  METHODS
  This study was carried out on 34 archival paraffin-embedded specimens of odontogenic cysts. We obtained the specimens from the Pathology Department of Babol University of Medical Sciences, Babol, Iran from March 2003 to February 2008. The specimens comprised 12 dentigerous cysts, 9 radicular cysts, and 13 keratocystic odontogenic tumors (KCOTs). The immunohistochemical technique was performed using the Envision system for evaluation of p63 expression.
  
  
  RESULTS
  The KCOT revealed the highest p63 expression and the differences between the 3 groups was statistically significant.
  
  
  CONCLUSIONS
  P63 expression might be helpful when identifying cyst types with more aggressive and invasive phenotype.
authors.affiliation: Department of Oral & Maxillofacial Pathology, Dental Materials Research Center, Dental Faculty, Babol University of Medical Sciences, PO Box 853, Babol, Mazandaran, Iran. ms_majidi79@yahoo.com
authors.forename: Maryam
authors.initials: M
authors.lastname: Seyedmajidi
authors.forename: Shahryar
authors.initials: S
authors.lastname: Shafaee
authors.forename: Ensieh
authors.initials: E
authors.lastname: Shafigh
authors.forename: Ali
authors.initials: A
authors.lastname: Bijani
authors.forename: Hamid
authors.initials: H
authors.lastname: Hamidi
mesh_terms: D003803:Dentigerous Cyst / Q000378:metabolism; D006801:Humans; D009807:Odontogenic Cysts / Q000378:metabolism*; D011842:Radicular Cyst / Q000378:metabolism; D014157:Transcription Factors / Q000378:metabolism*; D025521:Tumor Suppressor Proteins / Q000378:metabolism*
chemical_list: C115051:TP63 protein, human; D014157:Transcription Factors; D025521:Tumor Suppressor Proteins