title: The influence of cone-beam computed tomography and periapical radiographic evaluation on the assessment of periapical bone destruction in dog's teeth.
abstract: OBJECTIVE
  The aim of this study was to determine the influence of periapical radiographs, cone beam computed tomography (CBCT) sections, and cone beam volumetric data on the determination of periapical bone destruction in endodontically treated distal root canals of premolar canine teeth. Nontreated mesial roots were used as controls.
  
  
  METHODS
  Enterococcus faecalis strain (ATCC 29212) was inoculated into 30 root canals of 2 mongrel dogs to induce apical periodontitis. After 60 days, the root canals of the distal roots of the 11 mandibular and 4 maxillary premolars were endodontically treated (n = 15). The mesial root canals were used as controls (no treatment). The bone destruction was evaluated after 6 months by 5 evaluators using periapical radiographs and by CBCT (coronal and sagittal sections). After the experimental period, the area of the lesions in periapical radiographs and CBCT sections were measured in mm(2) using the ImageTool software. A single evaluator measured the volumetric data using the OsiriX software. The comparison between the diagnosis methods in treated root canals and controls was performed using parametric and nonparametric criteria. The Pearson correlation coefficient was computed between radiographic values and CBCT volumetric data in treated root canals and controls.
  
  
  RESULTS
  The results showed the presence of chronic apical periodontitis in every inoculated tooth. After 6 months, periapical radiographs, coronal CBCT sections, and volumetric data showed lower bone destruction in endodontically treated teeth in comparison with the control group (P < .05). The 5 evaluators found no differences between the apical periodontitis area of treated teeth and controls when CBCT sagittal sections were used (P > .05). No correlation was found between x-ray and CBCT volumetric values in treated root canals.
  
  
  CONCLUSIONS
  Although selected CBCT sagittal sections showed similar values of bone destruction in endodontically and nontreated root canals, volumetric CBCT data showed that periapical lesions of endodontically treated root canals had half of the volume of periapical lesions in nontreated root canals. No relationship could be found between the periapical values of bone destruction and volumetric data found in CBCT of treated rood canals.
authors.affiliation: Department of Endodontics, Dental School of Bauru, University of São Paulo, São Paulo, Brazil. ronaldordinola@usp.br
authors.forename: Ronald
authors.initials: R
authors.lastname: Ordinola-Zapata
authors.forename: Clovis M
authors.initials: CM
authors.lastname: Bramante
authors.forename: Marco H
authors.initials: MH
authors.lastname: Duarte
authors.forename: Luciana M P S
authors.initials: LM
authors.lastname: Ramos Fernandes
authors.forename: Ericson J
authors.initials: EJ
authors.lastname: Camargo
authors.forename: Ivaldo Gomes
authors.initials: IG
authors.lastname: de Moraes
authors.forename: Norberti
authors.initials: N
authors.lastname: Bernardineli
authors.forename: Rodrigo R
authors.initials: RR
authors.lastname: Vivan
authors.forename: Ana Lucia A
authors.initials: AL
authors.lastname: Capelozza
authors.forename: Roberto Brandão
authors.initials: RB
authors.lastname: Garcia
mesh_terms: D016301:Alveolar Bone Loss / Q000000981:diagnostic imaging* / Q000382:microbiology / Q000628:therapy; D000818:Animals; D001641:Bicuspid / Q000473:pathology; D002614:Chelating Agents / Q000627:therapeutic use; D054893:Cone-Beam Computed Tomography / Q000379:methods*; D004285:Dogs; D004492:Edetic Acid / Q000627:therapeutic use; D013293:Enterococcus faecalis / Q000502:physiology; D005899:Glass Ionomer Cements / Q000627:therapeutic use; D016908:Gram-Positive Bacterial Infections / Q000382:microbiology / Q000628:therapy; D006171:Gutta-Percha / Q000627:therapeutic use; D007091:Image Processing, Computer-Assisted / Q000379:methods; D021621:Imaging, Three-Dimensional / Q000379:methods; D010485:Periapical Periodontitis / Q000000981:diagnostic imaging* / Q000382:microbiology / Q000628:therapy; D016300:Radiography, Bitewing / Q000379:methods*; D019252:Radiography, Dental, Digital / Q000379:methods; D012387:Root Canal Filling Materials / Q000627:therapeutic use; D012388:Root Canal Irrigants / Q000627:therapeutic use; D018915:Root Canal Preparation / Q000379:methods; D012390:Root Canal Therapy / Q000379:methods; D013997:Time Factors
chemical_list: D002614:Chelating Agents; D005899:Glass Ionomer Cements; D012387:Root Canal Filling Materials; D012388:Root Canal Irrigants; D006171:Gutta-Percha; D004492:Edetic Acid