title: Secondary renal tubular acidosis in a Hereford calf.
abstract: A 3-month-old Hereford heifer calf was presented for lethargy. Blood gas analysis and plasma biochemical testing revealed severe metabolic acidosis, azotemia, hyponatremia, hyperchloremia, and normal anion gap. Results of a urinalysis were consistent with acute tubular necrosis with inadequate acidification of urine based on the degree of acidemia. Salmonella enterica serovar agona was cultured from both urine and feces. The calf was treated with intravenous polyionic fluids, bicarbonate, and antimicrobials. Acidosis and azotemia resolved, and 4 months following initial presentation the heifer was clinically normal.
authors.affiliation: Department of Medical Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI, USA. laura.hardefeldt@adelaide.edu.au
authors.forename: Laura Y
authors.initials: LY
authors.lastname: Hardefeldt
authors.forename: Keith P
authors.initials: KP
authors.lastname: Poulsen
authors.forename: Benjamin J
authors.initials: BJ
authors.lastname: Darien
mesh_terms: D000141:Acidosis, Renal Tubular / Q000188:drug therapy / Q000209:etiology / Q000382:microbiology / Q000662:veterinary*; D000818:Animals; D001639:Bicarbonates / Q000627:therapeutic use; D001784:Blood Gas Analysis; D002021:Buffers; D002417:Cattle; D002418:Cattle Diseases / Q000188:drug therapy / Q000209:etiology* / Q000382:microbiology; D005260:Female; D012481:Salmonella Infections, Animal / Q000150:complications* / Q000382:microbiology; D019779:Salmonella enterica
chemical_list: D001639:Bicarbonates; D002021:Buffers