title: Stress vulnerability in patients with drug allergy--psychological aspects revealed from some personal studies.
abstract: Previous studies revealed the fact that patients with allergic-type reactions to drugs display very frequently psychical disturbances, possibly in relation to the large amount of stress perceived by them. Some of these patients with psychiatric comorbidity show a disproportionate reaction, manifested as extensive psychosomatic disturbances, mimicking the psychic and somatic symptoms of a previous anaphylactic or anaphylactoid reaction, when a new drug or even when placebo preparations are given. The neurotic symptoms, very frequently encountered in patients with allergic-type reactions to drugs (including asthma patients) appear to be secondarily-induced by the anxious experience of the drug-provoked accident. The vulnerability to psychic stress, together with many life stressors events may represent a potential risk for developing drug allergy. Their main problem is the risk of repeating the allergic accidents, especially in patients with various comorbidity which need medication.
authors.affiliation: "Carol Davila" University of Medicine and Pharmacy, Department of Medical Psychology, Bucharest, Romania.
authors.forename: I B
authors.initials: IB
authors.lastname: Iamandescu
authors.forename: Liliana
authors.initials: L
authors.lastname: Diaconescu
mesh_terms: D001007:Anxiety; D003863:Depression; D004342:Drug Hypersensitivity / Q000150:complications* / Q000523:psychology*; D006801:Humans; D009497:Neurotic Disorders / Q000150:complications; D010465:Perception; D011581:Psychological Tests; D011602:Psychophysiologic Disorders / Q000150:complications; D013315:Stress, Psychological / Q000150:complications*