title: Recent developments and perspectives in palladium-catalyzed cyanation of aryl halides: synthesis of benzonitriles.
abstract: The palladium-catalyzed cyanation of Ar-X (X = I, Br, Cl, OTf, and H) allows for an efficient access towards benzonitriles. After its discovery in 1973 and following significant improvements in recent decades, this methodology has become nowadays the most popular for preparation of substituted aromatic nitriles. In this critical review, we summarize the important developments in this area from 2000 until 2010 (151 references).
authors.affiliation: Leibniz-Institut für Katalyse e.V. an der Universität Rostock, Albert-Einstein-Str. 29A, 18059 Rostock, Germany.
authors.forename: Pazhamalai
authors.initials: P
authors.lastname: Anbarasan
authors.forename: Thomas
authors.initials: T
authors.lastname: Schareina
authors.forename: Matthias
authors.initials: M
authors.lastname: Beller
mesh_terms: D002384:Catalysis; D060326:Chemistry Techniques, Synthetic / Q000379:methods*; D003486:Cyanides / Q000737:chemistry*; D009570:Nitriles / Q000138:chemical synthesis* / Q000737:chemistry; D010165:Palladium / Q000737:chemistry*
chemical_list: D003486:Cyanides; D009570:Nitriles; C430593:cyanohydrin; D010165:Palladium; C014356:benzonitrile