title: [Noninvasive estimation of the oxygen state of experimental tumor by diffuse optical spectroscopy].
abstract: The potentialities of diffuse optical spectroscopy for the noninvasive estimation of the oxygen state of experimental tumors have been demonstrated. The distribution of total, oxygenated and deoxygenated hemoglobin, as well as the level oxygen saturation of blood have been shown using two tumor models differing in the histological structure and functional characteristics. The results obtained by the optical method have been verified by immunohistochemical examination of tissue specimens with the exogenous hypoxia marker pimonidazole.
authors.forename: A G
authors.initials: AG
authors.lastname: Orlova
authors.forename: A V
authors.initials: AV
authors.lastname: Maslennikova
authors.forename: G Iu
authors.initials: GIu
authors.lastname: Golubiatnikov
authors.forename: V A
authors.initials: VA
authors.lastname: Kamenskiĭ
authors.forename: N M
authors.initials: NM
authors.lastname: Shakhova
authors.forename: A A
authors.initials: AA
authors.lastname: Babaev
authors.forename: L B
authors.initials: LB
authors.lastname: Snopova
authors.forename: I P
authors.initials: IP
authors.lastname: Ivanova
authors.forename: V I
authors.initials: VI
authors.lastname: Plekhanov
authors.forename: T I
authors.initials: TI
authors.lastname: Prianikova
authors.forename: I V
authors.initials: IV
authors.lastname: Turchin
mesh_terms: D000818:Animals; D009374:Neoplasms, Experimental / Q000378:metabolism* / Q000473:pathology; D010092:Oximetry / Q000379:methods*; D010100:Oxygen / Q000378:metabolism*; D010101:Oxygen Consumption; D010108:Oxyhemoglobins / Q000378:metabolism; D051381:Rats
chemical_list: D010108:Oxyhemoglobins; D010100:Oxygen