title: Orf parapoxvirus infection from a cat scratch.
abstract: A 53-year-old woman presented with an enlarging, tender, ulcerated nodule on her dorsal hand after being scratched by a stray kitten. Histology was consistent with orf parapoxvirus infection. The lesion resolved without scarring after several weeks of treatment with imiquimod 5 percent cream. Orf is a zoonosis transmitted to humans from sheep and goats by direct contact or by fomites. Transmission by cat scratch has not been previously described in the literature.
authors.affiliation: University of Utah, Department of Dermatology, Salt Lake City, Utah, USA.
authors.forename: Jonathan
authors.initials: J
authors.lastname: Frandsen
authors.forename: Mike
authors.initials: M
authors.lastname: Enslow
authors.forename: Anneli R
authors.initials: AR
authors.lastname: Bowen
mesh_terms: D000634:Aminoquinolines / Q000627:therapeutic use; D000818:Animals; D001706:Biopsy; D002415:Cats; D005260:Female; D006801:Humans; D000077271:Imiquimod; D007369:Interferon Inducers / Q000627:therapeutic use; D008875:Middle Aged; D009923:Orf virus / Q000302:isolation & purification*; D011213:Poxviridae Infections / Q000188:drug therapy / Q000473:pathology* / Q000635:transmission*; D016896:Treatment Outcome; D015047:Zoonoses / Q000635:transmission* / Q000821:virology
chemical_list: D000634:Aminoquinolines; D007369:Interferon Inducers; D000077271:Imiquimod