title: Urodynamic parameters development and complications of clean intermittent self-catheterization in Chinese schoolchildren with neurogenic underactive bladder.
abstract: OBJECTIVE
  To evaluate the urodynamic parameters, development of bladder function and complications of clean intermittent self-catheterization (CIC) in Chinese schoolchildren with neurogenic underactive bladder.
  
  
  METHODS
  Ninety-three children with neurogenic underactive bladder were successfully treated with CIC or combined with oxybutynin for two years follow-up. According to bladder compliance before CIC, they were subdivided into a normal bladder compliance (NBC) group and a low bladder compliance (LBC) group. Urodynamic parameters and complications were recorded.
  
  
  RESULTS
  At follow-up, the incidence of neurogenic detrusor overactivity was found to have significantly decreased in both groups. Moreover, maximum cystometric capacity (CC) and relatively safe CC in the NBC group was significantly higher than those before CIC. However, relatively safe CC was significantly lower than that before CIC, and detrusor leakage point pressure was significantly higher than that before CIC in the LBC group. The incidences of bacteriuria, vesicureteral reflux (VUR), febrile urinary tract infections (UTI) and macroscopic hematuria were, respectively, 62, 13, 25 and 15%, and those of VUR and febrile UTI in the LBC group were significantly higher than those in the NBC group.
  
  
  CONCLUSIONS
  For these cases, the complications of CIC are rare, and bladder compliance seems to be correlated with the development of bladder function and complications during CIC.
authors.affiliation: Department of Urology and Urodynamic Center, First Affiliated Hospital of Zhengzhou University, Zhengzhou City, China. qwwang@zzu.edu.cn
authors.forename: Qing Wei
authors.initials: QW
authors.lastname: Wang
authors.forename: Dong Kui
authors.initials: DK
authors.lastname: Song
authors.forename: Xue Pei
authors.initials: XP
authors.lastname: Zhang
authors.forename: Yu Dong
authors.initials: YD
authors.lastname: Wu
authors.forename: Rui Li
authors.initials: RL
authors.lastname: Zhang
authors.forename: Jin Xing
authors.initials: JX
authors.lastname: Wei
authors.forename: Jian Guo
authors.initials: JG
authors.lastname: Wen
mesh_terms: D002648:Child; D002675:Child, Preschool; D002681:China; D005260:Female; D005334:Fever; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008333:Mandelic Acids / Q000494:pharmacology; D013119:Spinal Cord Injuries / Q000150:complications; D016135:Spinal Dysraphism / Q000150:complications; D001743:Urinary Bladder / Q000503:physiopathology; D001750:Urinary Bladder, Neurogenic / Q000175:diagnosis / Q000188:drug therapy* / Q000503:physiopathology*; D014546:Urinary Catheterization; D014563:Urodynamics
chemical_list: D008333:Mandelic Acids; C005419:oxybutynin