title: Enantioselective iridium-catalyzed allylic substitutions with hydroxamic acid derivatives as N-nucleophiles.
abstract: Enantioselective Ir-catalyzed allylic aminations with hydroxamic acid derivatives are described. Catalysts were prepared in situ from [Ir(cod)Cl](2) or [Ir(dbcot)Cl](2), a phosphoramidite and base. In addition, pure (π-allyl)Ir complexes containing cod or dbcot as auxiliary ligands were used. Very high degrees of regio- and enantioselectivity were achieved. The reaction products were transformed into piperidine derivatives suited as precursors for aza-sugars.
authors.affiliation: Organisch-Chemisches Institut der Ruprecht-Karls-Universität Heidelberg, Heidelberg, Germany.
authors.forename: Martin
authors.initials: M
authors.lastname: Gärtner
authors.forename: Mascha
authors.initials: M
authors.lastname: Jäkel
authors.forename: Manuel
authors.initials: M
authors.lastname: Achatz
authors.forename: Christoph
authors.initials: C
authors.lastname: Sonnenschein
authors.forename: Olena
authors.initials: O
authors.lastname: Tverskoy
authors.forename: Günter
authors.initials: G
authors.lastname: Helmchen