title: Presence of HPV DNA in placenta and cervix of pregnant Mexican women.
abstract: OBJECTIVE
  To identify the presence of HPV DNA in cervical as well as in placental tissue of pregnant Mexican women and to determine which type is more frequent.
  
  
  METHODS
  In a cross-sectional study, 56 placental samples were obtained from 72 pregnant women. HPV DNA was extracted and amplified with polymerase chain reaction using a consensus primer and then identified by type using RsaI endonuclease. The main outcome measures were placenta with/without HPV relation and HPV types in placenta.
  
  
  RESULTS
  HPV DNA was identified in 75% of cervical tissue samples and 47.2% of placental tissue samples. Type 18 was the most frequently identified HPV type.
  
  
  CONCLUSIONS
  There was a higher frequency of HPV DNA found in the cervix of Mexican women during pregnancy than reported in the previous studies. Its identification in full-term placental tissue has no relation to the type of delivery in childbirth.
authors.affiliation: Obstetrics and Gynecology Service, Instituto de Seguridad Social al Servicio de los Trabajadores del Estado (ISSSTE), Colima, Colima, Mexico.
authors.forename: Oscar
authors.initials: O
authors.lastname: Uribarren-Berrueta
authors.forename: José
authors.initials: J
authors.lastname: Sánchez-Corona
authors.forename: Héctor
authors.initials: H
authors.lastname: Montoya-Fuentes
authors.forename: Benjamin
authors.initials: B
authors.lastname: Trujillo-Hernández
authors.forename: Clemente
authors.initials: C
authors.lastname: Vásquez
mesh_terms: D000293:Adolescent; D000328:Adult; D002584:Cervix Uteri / Q000737:chemistry / Q000821:virology*; D003430:Cross-Sectional Studies; D004279:DNA, Viral / Q000032:analysis / Q000378:metabolism*; D005260:Female; D006801:Humans; D008800:Mexico / Q000453:epidemiology; D030361:Papillomavirus Infections / Q000175:diagnosis* / Q000453:epidemiology / Q000821:virology; D010920:Placenta / Q000737:chemistry / Q000821:virology*; D011247:Pregnancy; D011256:Pregnancy Outcome; D055815:Young Adult
chemical_list: D004279:DNA, Viral