title: A floating thrombus in sinus of valsalva complicated with cardiogenic shock in a patient with plasminogen activator inhibitor 1 4G/5G polymorphism.
abstract: Thrombus in sinus of Valsalva is unusual reason for acute myocardial infarction. We demonstrated a case with floating thrombus in sinus of Valsalva obstructing the right coronary ostium intermittently, and causing cardiogenic shock. The patient was diagnosed with multiplane transesophageal echocardiography and treated successfully with surgical removal of mass. A homozygote polymorphism of plasminogen activator inhibitor (PAI) 1 4G/5G was found. This is the first report demonstrating a patient with PAI 1 polymorphism and thrombus of Valsalva complicated with cardiogenic shock.
authors.affiliation: Department of Cardiology, Faculty of Medicine, Canakkale Onsekiz Mart University, Canakkale, Turkey. serkankard@gmail.com
authors.forename: Serkan
authors.initials: S
authors.lastname: Saygi
authors.forename: Emin
authors.initials: E
authors.lastname: Alioglu
authors.forename: Mehmet Nuri
authors.initials: MN
authors.lastname: Karabulut
authors.forename: Ugur Onsel
authors.initials: UO
authors.lastname: Turk
authors.forename: Bahadir
authors.initials: B
authors.lastname: Kirilmaz
authors.forename: Nurullah
authors.initials: N
authors.lastname: Tuzun
authors.forename: Fahri
authors.initials: F
authors.lastname: Sahin
authors.forename: Buket
authors.initials: B
authors.lastname: Kosova
authors.forename: Istemihan
authors.initials: I
authors.lastname: Tengiz
mesh_terms: D001018:Aortic Diseases / Q000150:complications / Q000000981:diagnostic imaging* / Q000235:genetics; D004452:Echocardiography; D006801:Humans; D008297:Male; D008875:Middle Aged; D017395:Plasminogen Activator Inhibitor 1 / Q000235:genetics*; D011110:Polymorphism, Genetic; D012770:Shock, Cardiogenic / Q000209:etiology*; D012850:Sinus of Valsalva / Q000000981:diagnostic imaging*; D013927:Thrombosis / Q000150:complications / Q000000981:diagnostic imaging* / Q000235:genetics
chemical_list: D017395:Plasminogen Activator Inhibitor 1