title: Use of F-18 FDG PET/CT in non-Hodgkin lymphoma with central nervous system involvement.
abstract: Central nervous system (CNS) is a rare site of involvement by non-Hodgkin lymphoma (NHL). Therapeutic approach for primary and secondary CNS NHL is different and remains challenging. Therefore imaging data are essential at staging to discriminate these 2 clinical entities and during follow-up to assess therapy response. The adjunct role of positron emission tomography using F-18 fluorodeoxyglucose to morphologic imaging is still undefined. We report 2 didactic cases of primary and secondary CNS NHL assessed by F-18 fluorodeoxyglucose positron emission tomography. Metabolic imaging seems to be complementary to conventional imaging techniques for the extent-of-disease evaluation and therapy monitoring of CNS lesions.
authors.affiliation: Département de Médecine Nucléaire, Centre Léon-Bérard, Université de Lyon, Lyon, France. cimarell@lyon.fnclcc.fr
authors.forename: Sébastien
authors.initials: S
authors.lastname: Cimarelli
authors.forename: Catherine
authors.initials: C
authors.lastname: Sebban
authors.forename: Philippe
authors.initials: P
authors.lastname: Thiesse
authors.forename: Marie Pierre
authors.initials: MP
authors.lastname: Sunyach
authors.forename: Jean-Yves
authors.initials: JY
authors.lastname: Blay
authors.forename: Hervé
authors.initials: H
authors.lastname: Ghesquières
mesh_terms: D016543:Central Nervous System Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000503:physiopathology; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000000981:diagnostic imaging* / Q000473:pathology / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D049268:Positron-Emission Tomography; D014057:Tomography, X-Ray Computed
chemical_list: D019788:Fluorodeoxyglucose F18