title: Polyneuropathy due to cyclosporine A in patients with renal transplantation: a case report.
abstract: BACKGROUND
  Calcineurin inhibitor cyclosporine A (CsA) is a potent immunosuppressive agent. The side effects of CsA include nephrotoxicity, hypertension, hypertrichosis, infection, hyperpotassemia, and, to a lower extent, neuropathy.
  
  
  OBJECTIVE
  In this case report, we aimed to present a renal transplant patient with polyneuropathy (PNP) due to the use of CsA and with improvement when switched to rapamycin.
  
  
  METHODS
  In electromyography, axonal sensory PNP was detected. CsA was stopped and rapamycin was begun.
  
  
  RESULTS
  His complaints rapidly improved after using rapamycin.
  
  
  CONCLUSIONS
  Patients using CsA should be closely monitored for peripheral neuropathy and in case of toxicity, alternative immunosuppressive agents should be considered.
authors.affiliation: Department of Neurology, Faculty of Medicine, Yuzuncu Yil University, Van, Turkey.
authors.forename: Refah
authors.initials: R
authors.lastname: Sayin
authors.forename: Yasemin Usul
authors.initials: YU
authors.lastname: Soyoral
authors.forename: Reha
authors.initials: R
authors.lastname: Erkoc
mesh_terms: D016572:Cyclosporine / Q000009:adverse effects*; D004576:Electromyography; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects*; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D011115:Polyneuropathies / Q000139:chemically induced* / Q000175:diagnosis
chemical_list: D007166:Immunosuppressive Agents; D016572:Cyclosporine