title: Clinical and epidemiological profile of patients with multiple sclerosis in Uberaba, Minas Gerais, Brazil.
abstract: Multiple sclerosis (MS) is an immune-mediated disease that affects the central nervous system. Clinical presentation and prevalence vary widely around the world.
  
  
  OBJECTIVE
  To describe the clinical and epidemiological aspects of patients with MS in Uberaba (MG).
  
  
  METHODS
  We conducted a transversal descriptive study, with data analysis of 35 patients with MS.
  
  
  RESULTS
  Prevalence of MS was 12.5 cases/100,000 inhabitants, with a predominance in females (71.4%) and Caucasoid (85.7%). The current average age was (43.8 ys). The most common initial symptom was sensory (40%), followed by optical neuritis (25.7%). Expanded Disability Status Scale average score was 2.4. The relapsing-remitting form was predominant (88.6%), most (74.3%) were on immunomodulatory treatment and (40%) had college education.
  
  
  CONCLUSIONS
  Prevalence of MS in Uberaba (MG) is considered average in accordance to Kurtzke and Page and clinical features are consistent with most Brazilian studies.
authors.affiliation: Department of Neurology, Federal University of Triangulo Mineiro, Uberaba, MG, Brazil. neurologia@uftm.edu.br
authors.forename: Sônia Beatriz Félix
authors.initials: SB
authors.lastname: Ribeiro
authors.forename: Danilo Fonseca
authors.initials: DF
authors.lastname: Maia
authors.forename: João Batista
authors.initials: JB
authors.lastname: Ribeiro
authors.forename: Fabrízio Antônio Gomide
authors.initials: FA
authors.lastname: Cardoso
authors.forename: Cátia
authors.initials: C
authors.lastname: Silva
mesh_terms: D000328:Adult; D017668:Age of Onset; D001938:Brazil / Q000453:epidemiology; D003430:Cross-Sectional Studies; D004522:Educational Status; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000453:epidemiology* / Q000208:ethnology; D015995:Prevalence; D017678:Sex Distribution; D055815:Young Adult