title: Functionalization of luminescent cyclometalated iridium(III) polypyridine complexes with a fluorous moiety: photophysics, protein-binding, bioconjugation, and cellular uptake properties.
abstract: A new class of luminescent cyclometalated iridium(III) polypyridine fluorous complexes has been designed; the fluorous pendant not only plays an important role in the photophysical and biological properties of the complexes, but also allows the facile isolation of biomolecules labeled with these complexes with fluorous solid-phase extraction (FSPE).
authors.affiliation: Department of Biology and Chemistry, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong, People's Republic of China.
authors.forename: Siu-Kit
authors.initials: SK
authors.lastname: Leung
authors.forename: Hua-Wei
authors.initials: HW
authors.lastname: Liu
authors.forename: Kenneth Kam-Wing
authors.initials: KK
authors.lastname: Lo
mesh_terms: D000818:Animals; D002417:Cattle; D056831:Coordination Complexes / Q000737:chemistry* / Q000378:metabolism*; D005456:Fluorescent Dyes / Q000737:chemistry*; D006367:HeLa Cells; D006801:Humans; D007495:Iridium / Q000737:chemistry*; D018613:Microscopy, Confocal; D011485:Protein Binding; D011725:Pyridines / Q000737:chemistry*; D012709:Serum Albumin / Q000737:chemistry / Q000378:metabolism; D013050:Spectrometry, Fluorescence
chemical_list: D056831:Coordination Complexes; D005456:Fluorescent Dyes; D011725:Pyridines; D012709:Serum Albumin; D007495:Iridium