title: Correlation of electromyogram and muscle biopsy in myopathy of young age.
abstract: OBJECTIVE
  To investigate the accuracy of electromyogram (EMG) compared to muscle biopsy in young myopathic patients.
  
  
  METHODS
  Observational study.
  
  
  METHODS
  A university rehabilitation hospital.
  
  
  METHODS
  Cases (N=62) were included if the patient was 18 years or younger, and if data were available from muscle biopsy, EMG, and final clinical diagnosis.
  
  
  METHODS
  No intervention.
  
  
  METHODS
  Sensitivity of EMG.
  
  
  RESULTS
  EMG showed myopathic findings in 55 patients, and microscopy revealed myopathy in 50 patients and nonspecific findings in 5 patients. Twenty-eight out of 33 patients showed myogenic EMG findings with a conventional EMG, and histology revealed myopathy in 24 patients. In comparison, turns/amplitude analysis (TAA) with a conventional EMG detected myogenic findings in 27 of 29 patients. Twenty-six of these 27 patients showed myogenic findings in the biopsy.
  
  
  CONCLUSIONS
  We concluded that EMG is useful for the detection of myopathy in young patients. In addition, TAA may be helpful in cases of no definite conventional EMG findings and less cooperative patients.
authors.affiliation: Department of Rehabilitation Medicine and Rehabilitation Institute of Muscular Disease, Gangnam Severance Hospital, Yonsei University College of Medicine, 712 Eonjuro, Seoul, South Korea.
authors.forename: Jihoon
authors.initials: J
authors.lastname: Chang
authors.forename: Yoon Ghil
authors.initials: YG
authors.lastname: Park
authors.forename: Young-Chul
authors.initials: YC
authors.lastname: Choi
authors.forename: Jung Hwa
authors.initials: JH
authors.lastname: Choi
authors.forename: Jae Ho
authors.initials: JH
authors.lastname: Moon
mesh_terms: D000293:Adolescent; D001706:Biopsy; D002648:Child; D002675:Child, Preschool; D004576:Electromyography; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D018482:Muscle, Skeletal / Q000473:pathology* / Q000503:physiopathology*; D009135:Muscular Diseases / Q000175:diagnosis* / Q000473:pathology / Q000503:physiopathology