title: The palladium-catalyzed cyanation of indole C-H bonds with the combination of NH4HCO3 and DMSO as a safe cyanide source.
abstract: A palladium-catalyzed cyanation of the 3-position of indole sp(2) C-H bonds by the combination of NH(4)HCO(3) and DMSO as the "CN" source was achieved to provide aromatic nitriles in moderate to good yields with excellent regioselectivity. It represents a practical and safe cyanation method.
authors.affiliation: College of Chemistry & Materials Engineering, Wenzhou University, Wenzhou 325000, People's Republic of China.
authors.forename: Xinyi
authors.initials: X
authors.lastname: Ren
authors.forename: Jianbin
authors.initials: J
authors.lastname: Chen
authors.forename: Fan
authors.initials: F
authors.lastname: Chen
authors.forename: Jiang
authors.initials: J
authors.lastname: Cheng
mesh_terms: D001639:Bicarbonates / Q000737:chemistry*; D002244:Carbon / Q000737:chemistry; D002384:Catalysis; D003486:Cyanides / Q000737:chemistry*; D004121:Dimethyl Sulfoxide / Q000737:chemistry*; D006859:Hydrogen / Q000737:chemistry; D007211:Indoles / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*
chemical_list: D001639:Bicarbonates; D003486:Cyanides; D007211:Indoles; C027043:ammonium bicarbonate; D010165:Palladium; D002244:Carbon; D006859:Hydrogen; C030374:indole; D004121:Dimethyl Sulfoxide