title: [Associated risk factors of peritoneal metastasis in colorectal cancer].
abstract: OBJECTIVE
  To investigate risk factors associated with peritoneal metastasis in colorectal cancer.
  
  
  METHODS
  Clinicopathological data of 873 patients with colorectal cancer treated at the Nanfang Hospital of Southern Medical University from January 2003 to December 2008 were retrospectively analyzed. The associations between peritoneal metastasis and clinicopathological factors were evaluated by univariate analysis including independent-samples t test and χ(2) test, and multivariable logistic regression analysis.
  
  
  RESULTS
  Univariate analysis showed that age(P=0.032), tumor size(P=0.001), tumor differentiation(P=0.008), depth of bowel wall invasion(P=0.000), lymph node metastasis(P=0.000), serum carcinoembryonic antigen (CEA) level(P=0.003), and serum carbohydrate antigen 19-9(CA19-9) level(P=0.009) were associated with peritoneal metastasis. On multivariable logistic regression analysis, depth of bowel wall invasion, lymph node metastasis, serum CEA level and CA19-9 level remained as significant risk factors(all P<0.05).
  
  
  CONCLUSIONS
  Depth of bowel wall invasion, lymph node metastasis, serum CEA level, and CA19-9 level are risk factors for peritoneal metastasis in colorectal cancer.
authors.affiliation: Department of General Surgery, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
authors.forename: Feng
authors.initials: F
authors.lastname: Liu
authors.forename: Jiang
authors.initials: J
authors.lastname: Yu
authors.forename: Yao-ze
authors.initials: YZ
authors.lastname: Liang
authors.forename: Yan-feng
authors.initials: YF
authors.lastname: Hu
authors.forename: Ya-nan
authors.initials: YN
authors.lastname: Wang
authors.forename: Guo-xin
authors.initials: GX
authors.lastname: Li
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016009:Chi-Square Distribution; D015179:Colorectal Neoplasms / Q000175:diagnosis / Q000473:pathology*; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D010537:Peritoneum / Q000473:pathology; D011379:Prognosis; D012189:Retrospective Studies; D012307:Risk Factors; D055815:Young Adult