title: Acid controlled diastereoselectivity in asymmetric aldol reaction of cycloketones with aldehydes using enamine-based organocatalysts.
abstract: The example of syn-aldol reaction of cyclohexanone to aldehyde was demonstrated based on chiral diamine organocatalysts and it was realized either by increasing the molecular size of acid additives or by introducing a hydrogen-bond donor into acid additives.
authors.affiliation: State Key Laboratory of Catalysis, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, 457 Zhongshan Road, Dalian 116023, PR China.
authors.forename: Jinsuo
authors.initials: J
authors.lastname: Gao
authors.forename: Shiyang
authors.initials: S
authors.lastname: Bai
authors.forename: Qiang
authors.initials: Q
authors.lastname: Gao
authors.forename: Yan
authors.initials: Y
authors.lastname: Liu
authors.forename: Qihua
authors.initials: Q
authors.lastname: Yang