title: Urticaria and periorbital edema as prodromal presenting signs of acute hepatitis B infection.
abstract: A 34-year-old patient presented with giant, transient urticarial skin lesions and periorbital edema after a 3-month stay in DR Congo. Retrospective analysis of stored samples revealed that these signs were prodromal manifestations of acute hepatitis B infection. The hepatitis B infection was spontaneously cleared; the skin lesion did not recur.
authors.affiliation: Travel Clinic, Havenziekenhuis, Rotterdam, The Netherlands.
authors.forename: Rob
authors.initials: R
authors.lastname: van Aalsburg
authors.forename: Anne P J
authors.initials: AP
authors.lastname: de Pagter
authors.forename: Perry J
authors.initials: PJ
authors.lastname: van Genderen
mesh_terms: D000328:Adult; D015023:Democratic Republic of the Congo; D004487:Edema / Q000821:virology*; D006509:Hepatitis B / Q000097:blood / Q000150:complications*; D006515:Hepatitis B virus / Q000235:genetics / Q000302:isolation & purification; D006801:Humans; D008111:Liver Function Tests; D008297:Male; D009426:Netherlands; D009916:Orbital Diseases / Q000821:virology*; D016133:Polymerase Chain Reaction; D014195:Travel; D014581:Urticaria / Q000821:virology*