title: [Chilean results of the international registry of risk factors and treatment of unstable angina and non ST elevation myocardial infarction: ACCORD (ACute CORonary syndrome Descriptive study)].
abstract: BACKGROUND
  Guidelines for the management of unstable angina (UA) and non ST elevation myocardial infarction (NSTEMI) have been issued, however, current practices are unknown in Chile.
  
  
  OBJECTIVE
  To evaluate in a prospective cohort of NSTEMI patients the current practices, treatments and risk factors.
  
  
  METHODS
  One year prospective International non interventional registry, conducted in Chile between January 2005 and November 2006.
  
  
  RESULTS
  Two hundred thirty three Chilean NSTEMI patients were enrolled. Mortality was 5.5% at the end of the follow-up. Mean age was 61.6 years, and 30.6% were female. Most of the patients had at least one risk factor (98%): hypertension (84%), previous myocardial infarction (33%), dyslipidemia (54%), diabetes (33%), current smoking (30%). Main procedures during the hospitalization were coronary angiogram (67%), angioplasty (33%; 88% with stent) and coronary bypass surgery (7%). During procedures, 31% of patients received clopidogrel, and 4.2% glycoprotein Ilb/IIIa antagonists. Medical management was selected for 60% of patients. In comparison to men, women received less interventional procedures despite having more risk factors. Treatments prescribed at discharge were aspirin (97%), clopidogrel (49%), beta blockers (78%), diuretics (21%), lipid lowering agents (78%), oral hypoglycemic agents (13%) and insulin (9%). At the end of the 1-year follow-up, treatments were aspirin (84%), beta blockers (72%), diuretics (19%), and dual antiplatelet therapy with clopidogrel (16%).
  
  
  CONCLUSIONS
  A high prevalence of multiple risk factors for cardiovascular disease in Chilean patients with NSTEMI was observed. More aggressive primary and secondary preventive measures are urgently needed. Use of therapies proposed in the guidelines is high, but dual antiplatelet therapy is less than 50% at discharge and decreases during the one year-follow-up.
authors.affiliation: Hospital Dr. Hernán Henríquez, Universidad de La Frontera, Temuco, Chile. stockins@ufro.cl
authors.forename: Benjamín
authors.initials: B
authors.lastname: Stockins
authors.forename: Francisco
authors.initials: F
authors.lastname: Albornoz
authors.forename: Darío
authors.initials: D
authors.lastname: Martínez
authors.forename: Pabla
authors.initials: P
authors.lastname: Campos
authors.forename: Jorge
authors.initials: J
authors.lastname: Gajardo
authors.forename: Rubén
authors.initials: R
authors.lastname: Lamich
authors.forename: Leopoldo
authors.initials: L
authors.lastname: Manríquez
authors.forename: Víctor
authors.initials: V
authors.lastname: Pérez
authors.forename: Pamela
authors.initials: P
authors.lastname: Rojo
authors.forename: Pablo
authors.initials: P
authors.lastname: Sepúlveda
authors.forename: M Gabriela
authors.initials: MG
authors.lastname: Pumarino
authors.forename: Ramón
authors.initials: R
authors.lastname: Corbalán
mesh_terms: D000789:Angina, Unstable / Q000401:mortality / Q000628:therapy*; D002677:Chile / Q000453:epidemiology; D011307:Drug Prescriptions / Q000592:standards / Q000706:statistics & numerical data; D005260:Female; D005500:Follow-Up Studies; D019983:Guideline Adherence / Q000706:statistics & numerical data*; D006760:Hospitalization / Q000706:statistics & numerical data*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000401:mortality / Q000628:therapy*; D010351:Patient Discharge / Q000706:statistics & numerical data*; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use; D017410:Practice Guidelines as Topic; D011446:Prospective Studies; D012042:Registries; D012307:Risk Factors
chemical_list: D010975:Platelet Aggregation Inhibitors