title: Distribution of mosquitoes and mosquito-borne arboviruses in Yunnan Province near the China-Myanmar-Laos border.
abstract: Economic development and increased tourism in the southern region of Yunnan Province in China, adjacent to several countries in Southeast Asia, has increased the likelihood of import and export of vectors and vector-borne diseases. We report the results of surveillance of mosquitoes and mosquito-borne arboviruses along the border of China-Myanmar-Laos in 2005 and 2006, and information associating several arboviruses with infections and possibly disease in local human populations. Seventeen mosquito species representing four genera were obtained, and 14 strains of mosquito-borne viruses representing six viruses in five genera were isolated from Culex tritaeniorhynchus. In addition, IgM against Japanese encephalitis virus, Sindbis virus, Yunnan orbivirus and novel Banna virus was detected in acute-phase serum samples obtained from hospitalized patients with fever and encephalitis near the areas where the viruses were isolated. This investigation suggests that Japanese encephalitis virus, Sindbis virus, and lesser-known arboviruses circulate and may be infecting humans in the China-Myanmar-Laos border region.
authors.affiliation: State Key Laboratory for Infectious Disease Prevention and Control, Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control, 100 Yingxin Street, Xuanwu, Beijing, People's Republic of China. wangjinglin107@yahoo.com.cn
authors.forename: Jinglin
authors.initials: J
authors.lastname: Wang
authors.forename: Hailin
authors.initials: H
authors.lastname: Zhang
authors.forename: Xiaohong
authors.initials: X
authors.lastname: Sun
authors.forename: Shihong
authors.initials: S
authors.lastname: Fu
authors.forename: Huanqin
authors.initials: H
authors.lastname: Wang
authors.forename: Yun
authors.initials: Y
authors.lastname: Feng
authors.forename: Huanyu
authors.initials: H
authors.lastname: Wang
authors.forename: Qing
authors.initials: Q
authors.lastname: Tang
authors.forename: Guo-Dong
authors.initials: GD
authors.lastname: Liang
mesh_terms: D000818:Animals; D001103:Arboviruses / Q000145:classification / Q000302:isolation & purification*; D001483:Base Sequence; D002460:Cell Line; D002681:China; D006224:Cricetinae; D003465:Culex / Q000821:virology*; D017931:DNA Primers; D004591:Electrophoresis, Polyacrylamide Gel; D005455:Fluorescent Antibody Technique; D007303:Insect Vectors; D007812:Laos; D002052:Myanmar; D010802:Phylogeny; D020133:Reverse Transcriptase Polymerase Chain Reaction
chemical_list: D017931:DNA Primers