title: Finasteride-associated cataract and intraoperative floppy-iris syndrome.
abstract: A 47-year-old man who had been using finasteride for male pattern alopecia for 4 years complained of progressive bilateral blurring of vision. His general health had been good, and he was not on any other long-term medication. Examination showed bilateral anterior subcapsular cataracts. Phacoemulsification and insertion of intraocular lenses were performed, and both eyes showed features of intraoperative floppy-iris syndrome (IFIS), including undulation and billowing of the iris, iris prolapse, and pupil constriction. We believe the use of finasteride can be associated with cataract formation and IFIS. Ophthalmologists and physicians prescribing finasteride should be aware of this possible association.
  
  
  BACKGROUND
  Neither author has a financial or proprietary interest in any material or method mentioned.
authors.affiliation: Department of Ophthalmology, Union Hospital, Hong Kong, China. dralbertcmw@gmail.com
authors.forename: Albert Chak-Ming
authors.initials: AC
authors.lastname: Wong
authors.forename: Shiu Ting
authors.initials: ST
authors.lastname: Mak
mesh_terms: D058891:5-alpha Reductase Inhibitors / Q000009:adverse effects*; D000505:Alopecia / Q000188:drug therapy; D002386:Cataract / Q000139:chemically induced*; D018120:Finasteride / Q000009:adverse effects*; D006068:Gonioscopy; D006801:Humans; D007429:Intraocular Pressure; D007431:Intraoperative Complications; D007499:Iris Diseases / Q000139:chemically induced*; D019654:Lens Implantation, Intraocular; D007908:Lens, Crystalline / Q000187:drug effects*; D008297:Male; D008875:Middle Aged; D009123:Muscle Hypotonia / Q000139:chemically induced; D018918:Phacoemulsification; D011391:Prolapse
chemical_list: D058891:5-alpha Reductase Inhibitors; D018120:Finasteride