title: Differences in itch characteristics between psoriasis and atopic dermatitis patients: results of a web-based questionnaire.
abstract: Differences in itch characteristics between different inflammatory dermatoses are not well described. The aim of this study was to assess differences in itch characteristics between patients with psoriasis and atopic dermatitis using a previously validated web-based questionnaire that was made available through the National Psoriasis Foundation and National Eczema Association for Science and Education websites. Participants rated frequency and intensity of itch, associated symptoms, itch descriptors, and effect of scratching. A total of 524 subjects with atopic dermatitis and 195 subjects with psoriasis completed the survey. Atopic dermatitis responders experienced more frequent and more intense itch. Associated sweating and heat sensation were also more common in atopic dermatitis. Scratching was considered pleasurable in both atopic dermatitis and psoriasis; pleasurability correlated weakly with itch intensity in atopic dermatitis. Psoriasis respondents reported higher embarrassment associated with itch. Itch sensation is experienced differently among patients with atopic dermatitis and psoriasis. Future therapeutic interventions may be developed to target these differences.
authors.affiliation: Department of Dermatology, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
authors.forename: Jenna L
authors.initials: JL
authors.lastname: O'Neill
authors.forename: Yiong Huak
authors.initials: YH
authors.lastname: Chan
authors.forename: Stephen R
authors.initials: SR
authors.lastname: Rapp
authors.forename: Gil
authors.initials: G
authors.lastname: Yosipovitch
mesh_terms: D000328:Adult; D016009:Chi-Square Distribution; D003876:Dermatitis, Atopic / Q000150:complications* / Q000175:diagnosis / Q000523:psychology; D005260:Female; D006306:Health Surveys; D006801:Humans; D020407:Internet; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D010465:Perception; D057181:Pleasure; D011537:Pruritus / Q000175:diagnosis / Q000209:etiology* / Q000523:psychology; D011565:Psoriasis / Q000150:complications* / Q000175:diagnosis / Q000523:psychology; D011788:Quality of Life; D012684:Sensory Thresholds; D012720:Severity of Illness Index; D012752:Shame; D011795:Surveys and Questionnaires