title: Genetic composition of six miniSTR in a Brazilian Mulatto sample population.
abstract: The present study characterizes the genetic variability of Mulatto population based on the polymorphism of six miniSTR autosomal loci, known as Non Codis 01 and 02 (NC01 and NC02) and evaluate their applicability in forensic genetics. A sample of 102 unrelated Brazilian mulattoes were genotyped for miniSTR loci D1S1677, D2S441, D4S2364 (miniplex NC02) and 45 individuals for D10S1248, D14S1434, D22S1045 (miniplex NC01). No significant deviations from Hardy-Weinberg equilibrium expectations were detected. The combined power of discrimination (PD) and mean power of exclusion (PE) were 0.999996 and 0.98991, respectively. The results also support the effectiveness of the NC01and NC02 miniplexes for human identification.
authors.affiliation: UNT Center for Human Identification, University of North Texas Health Science Center, Forth Worth, TX 76107, USA. xaranda@hsc.unt.edu
authors.forename: Xavier G
authors.initials: XG
authors.lastname: Aranda
authors.forename: Caroline A C
authors.initials: CA
authors.lastname: Lage
authors.forename: John V
authors.initials: JV
authors.lastname: Planz
authors.forename: Arthur J
authors.initials: AJ
authors.lastname: Eisenberg
authors.forename: Rodrigo S
authors.initials: RS
authors.lastname: Moura-Neto
authors.forename: Rosane
authors.initials: R
authors.lastname: Silva
mesh_terms: D001938:Brazil; D016172:DNA Fingerprinting; D005006:Ethnicity / Q000235:genetics*; D005787:Gene Frequency; D014644:Genetic Variation; D005828:Genetics, Population; D005838:Genotype; D006801:Humans; D018895:Microsatellite Repeats