title: Ruthenium-catalyzed (2 + 2) intramolecular cycloaddition of allenenes.
abstract: We report a ruthenium-catalyzed (2 + 2) intramolecular cycloaddition of allenes and alkenes. We have found that the use of the ruthenium complex RuH(2)Cl(2)(P(i)Pr(3))(2), which has previously gone unnoticed in catalytic applications, is crucial for the observed reactivity. The reaction proceeds under mild conditions and is fully diastereoselective, providing a practical entry to a variety of bicyclo[3.2.0]heptane skeletons featuring cyclobutane rings.
authors.affiliation: Departamento de Química Orgánica y Centro Singular de Investigación en Química Biológica y Materiales Moleculares, Unidad Asociada al CSIC, Universidad de Santiago de Compostela, 15782 Santiago de Compostela, Spain.
authors.forename: Moisés
authors.initials: M
authors.lastname: Gulías
authors.forename: Alba
authors.initials: A
authors.lastname: Collado
authors.forename: Beatriz
authors.initials: B
authors.lastname: Trillo
authors.forename: Fernando
authors.initials: F
authors.lastname: López
authors.forename: Enrique
authors.initials: E
authors.lastname: Oñate
authors.forename: Miguel A
authors.initials: MA
authors.lastname: Esteruelas
authors.forename: José L
authors.initials: JL
authors.lastname: Mascareñas