title: Effects of aerobic training during hemodialysis on heart rate variability and left ventricular function in end-stage renal disease patients.
abstract: BACKGROUND
  Decreased heart rate variability (HRV) in patients with end stage renal disease (ESRD) undergoing hemodialysis is predictive of cardiac death, especially due to sudden death.
  
  
  OBJECTIVE
  To evaluate the effects of aerobic training during hemodialysis on HRV and left ventricular function in ESRD patients.
  
  
  METHODS
  Twenty two patients were randomized into two groups: exercise (n = 11; 49.6 ± 10.6 years; 4 men) and control (n = 11; 43.5 ± 12.8; 4 men). Patients assigned to the exercise group were submitted to aerobic training, performed during the first two hours of hemodialysis, three times weekly, for 12 weeks. HRV and left ventricular function were assessed by 24 hours Holter monitoring and echocardiography, respectively.
  
  
  RESULTS
  After 12 weeks of protocol, no significant differences were observed in time and frequency domains measures of HRV in both groups. The ejection fraction improved non-significantly in exercise group (67.5 ± 12.6% vs. 70.4 ± 12%) and decreased non-significantly in control group (73.6 ± 8.4% vs. 71.4 ± 7.6%).
  
  
  CONCLUSIONS
  A 12-week aerobic training program performed during hemodialysis did not modify HRV and did not significantly improve the left ventricular function.
authors.affiliation: Federal Institute of Education, Science and Technology of Southeast of Minas Gerais. mayconreboredo@yahoo.com.br
authors.forename: Maycon de Moura
authors.initials: Mde M
authors.lastname: Reboredo
authors.forename: Bruno do Valle
authors.initials: Bdo V
authors.lastname: Pinheiro
authors.forename: José Alberto
authors.initials: JA
authors.lastname: Neder
authors.forename: Maria Priscila Wermelinger
authors.initials: MP
authors.lastname: Ávila
authors.forename: Maria Lídia de Borges
authors.initials: ML
authors.lastname: Araujo E Ribeiro
authors.forename: Adriano Fernandes
authors.initials: AF
authors.lastname: de Mendonça
authors.forename: Mariane Vaz
authors.initials: MV
authors.lastname: de Mello
authors.forename: Ana Clara Cattete
authors.initials: AC
authors.lastname: Bainha
authors.forename: José
authors.initials: J
authors.lastname: Dondici Filho
authors.forename: Rogério Baumgratz
authors.initials: RB
authors.lastname: de Paula
mesh_terms: D000328:Adult; D005081:Exercise Therapy; D005260:Female; D006339:Heart Rate; D006801:Humans; D007676:Kidney Failure, Chronic / Q000503:physiopathology* / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis; D016277:Ventricular Function, Left