title: Immune Modulation by Mesenchymal Stem Cells.
abstract: SUMMARY: Mesenchymal stem cells (MSCs) and their stromal progeny may be considered powerful regulatory cells, a sort of dendritic cell counterpart, which influence all the main immune effectors and functional roles in vivo, as well as potential applications in the treatment of a number of human immunological diseases. By choosing MSC tissue origin, cell dose, administration route, and treatment schedule, all the potential side effects related to MSC use, including tumor growth enhancement, have to be well considered to maximize the benefits of MSC-depen-dent immune regulation without significant risks for the patients.
authors.affiliation: Stem Cell Research Laboratory, Section of Hematology, Department of Clinical and Experimental Medicine, University of Verona, Italy.
authors.forename: Francesco
authors.initials: F
authors.lastname: Bifari
authors.forename: Veronica
authors.initials: V
authors.lastname: Lisi
authors.forename: Elda
authors.initials: E
authors.lastname: Mimiola
authors.forename: Annalisa
authors.initials: A
authors.lastname: Pasini
authors.forename: Mauro
authors.initials: M
authors.lastname: Krampera