title: Polycyclic aromatic hydrocarbons and hydroxylated metabolites in the muscle tissue of Eurasian perch (Perca fluviatilis) through dietary exposure during a 56-day period.
abstract: Eurasian perch (Perca fluviatilis) was exposed trophically to phenanthrene, pyrene and benzo[a]pyrene. Accumulation kinetics in the muscle tissue of parent PAHs and hydroxylated metabolites were established for 56 days at 3 levels of exposure (0, 100 and 500 μg/kg BW). Benzo[a]pyrene and 3-hydroxy-benzo[a]pyrene were not detected in the muscles. During exposure, there was an increase in phenanthrene, pyrene and their hydroxylated metabolites in the muscle tissue. Low transfer to muscle tissue was observed at equilibrium for phenanthrene (4.4±0.6% and 2.7±0.8%) and pyrene (1.0±0.2% and 0.33±0.09%), depending on the concentrations in the spiked feed.
authors.affiliation: Nancy Université, INRA, UR AFPA, 2 Avenue de la Forêt de Haye, B.P. 172, F-54505 Vandœuvre-lès-Nancy cedex, France. alazartigues@yahoo.fr
authors.forename: Angélique
authors.initials: A
authors.lastname: Lazartigues
authors.forename: Marielle
authors.initials: M
authors.lastname: Thomas
authors.forename: Christine
authors.initials: C
authors.lastname: Grandclaudon
authors.forename: Jean
authors.initials: J
authors.lastname: Brun-Bellut
authors.forename: Cyril
authors.initials: C
authors.lastname: Feidt
mesh_terms: D000818:Animals; D001564:Benzo(a)pyrene / Q000378:metabolism; D004784:Environmental Monitoring; D020387:Food Chain; D006900:Hydroxylation; D009132:Muscles / Q000378:metabolism*; D010471:Perches / Q000254:growth & development / Q000378:metabolism*; D010616:Phenanthrenes / Q000378:metabolism; D011084:Polycyclic Aromatic Hydrocarbons / Q000008:administration & dosage / Q000378:metabolism*; D011721:Pyrenes / Q000378:metabolism; D014874:Water Pollutants, Chemical / Q000008:administration & dosage / Q000378:metabolism*
chemical_list: D010616:Phenanthrenes; D011084:Polycyclic Aromatic Hydrocarbons; D011721:Pyrenes; D014874:Water Pollutants, Chemical; D001564:Benzo(a)pyrene; C031181:phenanthrene; C030984:pyrene