title: N1, P2 and T-complex of the auditory brain event-related potentials to tones with varying rise times in adults with and without dyslexia.
abstract: Dyslexia is a learning difficulty affecting the acquisition of fluent reading and spelling skills due to poor phonological processing. Underlying deficits in processing sound rise time have also been found in children and adults with dyslexia. However, the neural basis for these deficits is unknown. In the present study event-related potentials were used to index neural processing and examine the effect of rise time manipulation on the obligatory N1, T-complex and P2 responses in English speaking adults with and without dyslexia. The Tb wave of the T-complex showed differences between groups, with the amplitudes for Tb becoming less negative with increased rise time for the participants with dyslexia only. Frontocentral N1 and P2 did not show group effects. Enhanced Tb amplitude that is modulated by rise time could indicate altered neural networks at the lateral surface of the superior temporal gyrus in adults with dyslexia.
authors.affiliation: Centre for Neuroscience in Education, University of Cambridge, UK. jarmo.hamalainen@jyu.fi
authors.forename: Jarmo A
authors.initials: JA
authors.lastname: Hämäläinen
authors.forename: Tim
authors.initials: T
authors.lastname: Fosker
authors.forename: Dénes
authors.initials: D
authors.lastname: Szücs
authors.forename: Usha
authors.initials: U
authors.lastname: Goswami
mesh_terms: D000161:Acoustic Stimulation / Q000379:methods; D000328:Adult; D001307:Auditory Perception / Q000502:physiology*; D001921:Brain / Q000503:physiopathology*; D001931:Brain Mapping; D004192:Discrimination, Psychological; D004410:Dyslexia / Q000473:pathology*; D004569:Electroencephalography / Q000379:methods; D005072:Evoked Potentials, Auditory / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011930:Reaction Time / Q000502:physiology*; D011932:Reading; D013016:Sound; D055815:Young Adult