title: Contemporary management of atherosclerotic renovascular disease: before and after ASTRAL.
abstract: Atheromatous renovascular disease is an increasingly common diagnosis in our ageing population. Although there is a wide spread of experience in its treatment, the evidence base is heterogeneous and inconclusive. The Angioplasty and Stenting for Renal Artery Lesions trial has provided some, but not all, answers regarding the place of renal revascularization therapy and has also raised more questions and generated further debate. We present a brief review of the significance of atheromatous renovascular disease, discussion of historical treatments, a short analysis of Angioplasty and Stenting for Renal Artery Lesions, and an exploration of where future research lies.
authors.affiliation: Renal Department, Salford Royal Hospital, Salford, Greater Manchester, UK.
authors.forename: James
authors.initials: J
authors.lastname: Ritchie
authors.forename: Constantina
authors.initials: C
authors.lastname: Chrysochou
authors.forename: Philip A
authors.initials: PA
authors.lastname: Kalra
mesh_terms: D017130:Angioplasty; D050197:Atherosclerosis / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy*; D015415:Biomarkers; D001918:Brachytherapy; D004617:Embolism / Q000517:prevention & control; D006801:Humans; D007674:Kidney Diseases / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy*; D015995:Prevalence; D011379:Prognosis; D015607:Stents
chemical_list: D015415:Biomarkers