title: Oral and jaw lymphoma in an Iranian population.
abstract: BACKGROUND
  Lymphoma is the second most common malignancy of head and neck. Many studies have been carried out in different population groups to detect the subtypes of oral and jaw lymphoma, but such research has not been conducted in Iran. The purpose of this study was to determine the subtypes of oral and jaw lymphoma by immunohistochemistry.
  
  
  METHODS
  A total of 36 paraffin-embedded blocks (25 males and 11 females) with primary diagnosis of non-Hodgkin lymphoma were studied by immunohistochemical markers according to cellular morphology.
  
  
  RESULTS
  The frequencies were diffuse large B-cell (41.1%), low-grade B-cell (35.2%), peripheral T-cell (11.7%), Burkitt (5.8%), and Hodgkin lymphomas (5.8%). The involved sites were salivary gland (26.4%), maxillary bone (23.5%), mandibular soft tissues (17.6%), maxillary sinus (14.7%), mandibular bone (8.8%), tonsils and tongue (5.7%), and lip and vestibule (2.9%), and 2 cases (5.5%) turned out to be undifferentiated carcinomas. The most common lymphomas in male and females were diffuse large B-cell and low-grade B-cell lymphomas, respectively.
  
  
  CONCLUSIONS
  The epidemiology of different types of oral lymphoma in a sample of Iranian population was not similar with other populations of the world. Immunohistochemistry and molecular methods are required to prove the diagnosis in addition to typing of lymphoma.
authors.affiliation: Oral & Maxillofacial Pathology Department, Faculty of Dentistry, Mashhad University of Medical Sciences and Dental Research Center, Mashhad, Iran.
authors.forename: Nooshin
authors.initials: N
authors.lastname: Mohtasham
authors.forename: Shahab
authors.initials: S
authors.lastname: Babakoohi
authors.forename: Maryam
authors.initials: M
authors.lastname: Sarraf-Yazdy
authors.forename: Maryam
authors.initials: M
authors.lastname: Sarraf-Yadzy
authors.forename: Bardia
authors.initials: B
authors.lastname: Sadr
authors.forename: Kamran
authors.initials: K
authors.lastname: Ghaffarzadegan
authors.forename: Atena
authors.initials: A
authors.lastname: Shiva
authors.forename: Hamid Abbaszadeh
authors.initials: HA
authors.lastname: Bidokhty
authors.forename: Kambiz
authors.initials: K
authors.lastname: Kamyab-Hesari
authors.forename: Seyed Majed
authors.initials: SM
authors.lastname: Mortazavi
authors.forename: Mansour
authors.initials: M
authors.lastname: Nassiri-Kashani
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000704:Analysis of Variance; D002648:Child; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D005260:Female; D006258:Head and Neck Neoplasms / Q000453:epidemiology*; D006801:Humans; D007124:Immunoenzyme Techniques; D007223:Infant; D007492:Iran / Q000453:epidemiology; D008228:Lymphoma, Non-Hodgkin / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies