title: Echo-endoscopy: new therapeutic frontiers.
abstract: Endoscopic ultrasound (EUS) has been established as a valuable diagnostic modality as it offers high-resolution imaging and fine-needle biopsy, which is essential in detecting and staging malignancies. Since the introduction of EUS-guided fine needle aspiration (EUS-FNA) in 1992, numerous novel EUS-based interventions and techniques have emerged. Currently, established interventional EUS techniques include celiac plexus block and neurolysis, drainage of pancreatic pseudocysts and pelvic fluid collections, and implantation of fiducial markers and radioactive seeds into the malignant tumors. Emerging EUS-guided experimental techniques include antitumor injection, ablation of tumors, and vascular access. Diagnostic and therapeutic access to the biliary tree and pancreatic duct is increasingly being used for failed ERCP procedures or inaccessible ducts. Interventional EUS is a very promising technique with many potential applications. The future holds promise for substantial progress in EUS-guided therapeutic interventions and their applications in clinical gastroenterology.
authors.affiliation: Division of Gastroenterology and Hepatology, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202-5149, USA.
authors.forename: C M
authors.initials: CM
authors.lastname: Cho
authors.forename: J
authors.initials: J
authors.lastname: Dewitt
authors.forename: M
authors.initials: M
authors.lastname: Al-Haddad
mesh_terms: D001340:Autonomic Nerve Block / Q000379:methods; D044963:Biopsy, Fine-Needle / Q000379:methods; D017115:Catheter Ablation / Q000639:trends; D002447:Celiac Plexus / Q000000981:diagnostic imaging / Q000601:surgery; D004322:Drainage; D019160:Endosonography / Q000379:methods / Q000639:trends*; D057918:Fiducial Markers / Q000639:trends; D006801:Humans; D015552:Injections, Intralesional / Q000639:trends; D007457:Iodine Radioisotopes / Q000008:administration & dosage; D009369:Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery*; D010192:Pancreatic Pseudocyst / Q000000981:diagnostic imaging / Q000601:surgery; D010388:Pelvis / Q000000981:diagnostic imaging / Q000601:surgery; D011237:Predictive Value of Tests; D012680:Sensitivity and Specificity; D016896:Treatment Outcome; D018084:Ultrasonography, Interventional / Q000639:trends
chemical_list: D007457:Iodine Radioisotopes