title: Clinico-pathological profile of head and neck malignancies at University College Hospital, Ibadan, Nigeria.
abstract: BACKGROUND
  This retrospective study analysed head and neck malignancies seen over a 19-year period at the University College Hospital, Ibadan.
  
  
  METHODS
  One thousand, one hundred and ninety two patients with head and neck malignancies were analysed according to age, gender, topography and histology.
  
  
  RESULTS
  There was an annual hospital frequency of 62 cases per year. The overall mean age for these malignancies was 43.9 (SD ± 19.3) years. The lesions from the respiratory tract were the most frequent (43.2%) of all cases. The palate was the most frequent intra-oral site (13.8%). Epithelial malignancies constituted 73.4% of all cases with a male: female ratio of 2:1, a mean age of 48.1 (SD ± 17.5) years and were mostly located in the larynx (19.7%). Lymphomas constituted 17.5% of all head and neck cancers with a male: female ratio of 1.6:1, a mean age of 35.1 (SD ± 20.6) years and nodal involvement (39.7%) was most common. Sarcomas constituted 8.9% of all malignancies with a male: female ratio of 1.5:1, mean age of 27.1 (SD ± 16.7) years and the maxillofacial bones (42.5%) were most commonly involved. Neuroendocrine malignancies accounted for 0.2% of head and neck malignancies with a male: female ratio of 1:1, a mean age of 28.5 (SD ± 6.4) years and both cases involved the nose.
  
  
  CONCLUSIONS
  This study has further confirmed that carcinomas remain the most frequent cancers of the head and neck region in south-western Nigeria.
authors.affiliation: Department of Oral Pathology, University College Hospital, University of Ibadan, Ibadan, Oyo state, Nigeria. perakin80@hotmail.com
authors.forename: Akinyele O
authors.initials: AO
authors.lastname: Adisa
authors.forename: Bukola F
authors.initials: BF
authors.lastname: Adeyemi
authors.forename: Abideen O
authors.initials: AO
authors.lastname: Oluwasola
authors.forename: Bamidele
authors.initials: B
authors.lastname: Kolude
authors.forename: Effiong E U
authors.initials: EE
authors.lastname: Akang
authors.forename: Jonathan O
authors.initials: JO
authors.lastname: Lawoyin
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D005260:Female; D006258:Head and Neck Neoplasms / Q000175:diagnosis* / Q000453:epidemiology; D006785:Hospitals, University / Q000706:statistics & numerical data*; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging / Q000379:methods*; D009549:Nigeria / Q000453:epidemiology; D015995:Prevalence; D012189:Retrospective Studies; D017678:Sex Distribution; D055815:Young Adult