title: [Apoptosis-inducing action of antituberculosis drugs of the main group in vitro].
abstract: The influence of the main antituberculosis drugs (isoniazid, rifampicin, ethambutol) on in vitro apoptosis of peripheral blood lymphocytes from patients with pulmonary tuberculosis was researched. It was shown that all the investigated drugs induced apoptotic death of the lymphocytes in vitro, that could result in disturbance of antigen-specific response formation in pulmonary tuberculosis.
authors.forename: O A
authors.initials: OA
authors.lastname: Vasilyeva
authors.forename: V A
authors.initials: VA
authors.lastname: Serebryakova
authors.forename: O I
authors.initials: OI
authors.lastname: Urazova
authors.forename: V V
authors.initials: VV
authors.lastname: Novitsky
authors.forename: T E
authors.initials: TE
authors.lastname: Kononova
authors.forename: I O
authors.initials: IO
authors.lastname: Naslednikova
mesh_terms: D000995:Antitubercular Agents / Q000009:adverse effects*; D017209:Apoptosis / Q000187:drug effects*; D004977:Ethambutol / Q000009:adverse effects*; D006801:Humans; D007538:Isoniazid / Q000009:adverse effects*; D008214:Lymphocytes / Q000187:drug effects*; D012293:Rifampin / Q000009:adverse effects*; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy
chemical_list: D000995:Antitubercular Agents; D004977:Ethambutol; D007538:Isoniazid; D012293:Rifampin