title: Enantioselective synthesis of alkaloids from phenylglycinol-derived lactams.
abstract: This review is focused on recent synthetic achievements and ongoing work in our laboratory using phenylglycinol-derived oxazolopiperidone lactams as starting materials for the enantioselective synthesis of piperidine-containing alkaloids: madangamines, 2,5-disubstituted decahydroquinoline and 1-substituted tetrahydroisoquinoline alkaloids, the indole alkaloids 20S- and 20R-dihydrocleavamine and quebrachamine, and indole alkaloids of the uleine and silicine groups.
authors.affiliation: Laboratory of Organic Chemistry, Faculty of Pharmacy, University of Barcelona, Av. Joan XXIII s/n, 08028 Barcelona, Spain. amat@ub.edu
authors.forename: Mercedes
authors.initials: M
authors.lastname: Amat
authors.forename: Núria
authors.initials: N
authors.lastname: Llor
authors.forename: Rosa
authors.initials: R
authors.lastname: Griera
authors.forename: Maria
authors.initials: M
authors.lastname: Pérez
authors.forename: Joan
authors.initials: J
authors.lastname: Bosch
mesh_terms: D000470:Alkaloids / Q000138:chemical synthesis*; D032701:Biomimetics; D004983:Ethanolamines; D005998:Glycine / Q000031:analogs & derivatives* / Q000737:chemistry; D007769:Lactams / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000470:Alkaloids; D004983:Ethanolamines; D007769:Lactams; C005332:N-phenylethanolamine; D005998:Glycine