title: Haemodynamic effects of negative pressure wound therapy when using a rigid barrier to prevent heart rupture.
abstract: Right ventricular heart rupture is a devastating complication associated with negative pressure wound therapy (NPWT) in cardiac surgery. The use of a rigid barrier has been suggested to offer protection against this lethal complication by preventing the heart from being drawn up and damaged by the sharp sternum bone edges. The aim of this study was to investigate the haemodynamic effects of placing a rigid barrier over the heart to protect it from rupture during NPWT. Eight pigs underwent median sternotomy followed by NPWT at --70 and --120 mmHg, using foam, with or without a rigid plastic disc between the heart and the sternal edges. The heart frequency, cardiac output, mean systemic arterial pressure, mean pulmonary artery pressure, central venous pressure and left atrial pressure were recorded. Cardiac output was not affected by NPWT, regardless of whether a rigid barrier was used. Heart frequency decreased during NPWT without a disc, and showed a tendency towards a decrease when using a rigid disc. The blood pressure decreased during NPWT without a disc, and showed only a tendency towards a decrease when a disc was inserted between the heart and the sternum. In conclusion, the results of this haemodynamic study show that a rigid disc can safely be placed over the heart during NPWT, to prevent heart rupture. The haemodynamic effects of NPWT in sternotomy wounds are slightly reduced by the presence of the rigid disc.
authors.affiliation: Department of Cardiothoracic Surgery, Lund University Hospital, Lund, Sweden. sandra.lindstedt@skane.se
authors.forename: Sandra
authors.initials: S
authors.lastname: Lindstedt
authors.forename: Richard
authors.initials: R
authors.lastname: Ingemansson
authors.forename: Malin
authors.initials: M
authors.lastname: Malmsjo
mesh_terms: D000818:Animals; D006348:Cardiac Surgical Procedures / Q000009:adverse effects / Q000379:methods; D004195:Disease Models, Animal; D006341:Heart Rupture / Q000209:etiology / Q000503:physiopathology / Q000517:prevention & control*; D006352:Heart Ventricles; D006439:Hemodynamics / Q000502:physiology*; D054843:Negative-Pressure Wound Therapy / Q000009:adverse effects*; D011183:Postoperative Complications; D019736:Prostheses and Implants; D011474:Prosthesis Design; D056346:Sternotomy / Q000009:adverse effects*; D013552:Swine; D014945:Wound Healing