title: Complex regional pain syndrome type 1 in a child with migraine.
abstract: Complex regional pain syndrome type 1 is a rare painful syndrome in children involving an extremity which consists of pain out of proportion to the cause, loss of function, and significant evidence of autonomic dysfunction. We report a child, a known case of migraine who presented with spontaneous onset pain and sudomotor changes in an extremity not preceded by any trauma. A good clinical eye is required for the identification and diagnosis of this underreported condition to prevent doing extensive investigations. The coexistence of migraine and complex regional pain syndrome type 1 in a patient is interesting and is probably due to the common underlying pathophysiological abnormalities involving central serotonin activity and neurogenic inflammatory mechanisms.
authors.affiliation: Division of Pediatric Neurology and Neurodevelopment, Department of Pediatrics, Advanced Pediatric Center, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
authors.forename: Munni
authors.initials: M
authors.lastname: Ray
authors.forename: P D
authors.initials: PD
authors.lastname: Singhi
mesh_terms: D002648:Child; D015897:Comorbidity; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008881:Migraine Disorders / Q000175:diagnosis* / Q000503:physiopathology; D010147:Pain Measurement; D012019:Reflex Sympathetic Dystrophy / Q000175:diagnosis* / Q000503:physiopathology