title: Methyl 3-(1H-indole-3-carboxamido)propionate hemihydrate.
abstract: The title compound, C(13)H(14)N(2)O(3)·0.5H(2)O, was synthesized by the condensation of methyl 3-amino-propionate with 3-trichloro-acetyl-indole. The two organic mol-ecules in the asymmetric unit are both close to planar, with r.m.s. deviations from the best fit plane through all of the non-H atoms of 0.004 (2) Å for mol-ecule A and 0.006 (1) Å for mol-ecule B. Also, the five- and six-membered rings of the indole systems are inclined at 1.67 (8) and 1.50 (8)° in mol-ecules A and B, respectively. In the crystal structure, the organic molecules are connected by inter-molecular N-H⋯O hydrogen bonds, forming chains. O-H⋯O and N-H⋯O hydrogen-bond inter-actions involving the water molecules inter-link these chains, forming double chains approximately parallel to the a axis.
authors.affiliation: Department of Chemistry, Jinan University, Guangzhou, Guangdong 510632, People's Republic of China.
authors.forename: Gang
authors.initials: G
authors.lastname: Huang
authors.forename: Xing Yan
authors.initials: XY
authors.lastname: Xu
authors.forename: Xiang Chao
authors.initials: XC
authors.lastname: Zeng
authors.forename: Le
authors.initials: L
authors.lastname: Zheng
authors.forename: Kai Ping
authors.initials: KP
authors.lastname: Li