title: [Determination of 46 plasticizers in food contact polyvinyl chloride packaging materials and their migration into food simulants by gas chromatography-mass spectrometry].
abstract: A gas chromatography-mass spectrometry (GC-MS) method was developed for the determination of 46 plasticizers in food contact polyvinyl chloride (PVC) packaging materials and their migration into food simulants, i. e. water, 3% acetic acid, 10% ethanol and olive oil. Plasticizers in the PVC packaging materials, aqueous food simulants and olive oil food simulants were extracted by the dissolution-precipitation, liquid-liquid extraction and gel permeation chromatography (GPC) approaches, respectively. The extracts were analyzed by GC-MS in selective ion monitoring (SIM) mode and quantified using the external standard method. The cal-ibration curves were linear in the ranges of 0.1-2.0 mg/L with the correlation coefficients of 0.9910-0. 999 9. The limits of detection were from 0. 005 mg/kg to 0. 05 mg/kg ( S/N = 5 ). The recoveries at 3 spiked levels were 69.51%-107. 21% and the relative standard deviations (RSDs n = 6) ranged from 3.53% to 18.95%. These results show that this method is fast, sensitive and accurate for the qualitative and quantitative determination of plasticizers in food contact plastic products and 4 types of food simulants.
authors.affiliation: Hebei Entry-Exit Inspection and Quarantine Bureau, Shjiazhuang 050051, China.
authors.forename: Chunhai
authors.initials: C
authors.lastname: Guo
authors.forename: Haibo
authors.initials: H
authors.lastname: Bo
authors.forename: Wenzhong
authors.initials: W
authors.lastname: Duan
authors.forename: Haitao
authors.initials: H
authors.lastname: Jia
authors.forename: Ruichun
authors.initials: R
authors.lastname: Chen
authors.forename: Yusong
authors.initials: Y
authors.lastname: Ma
authors.forename: Lianfeng
authors.initials: L
authors.lastname: Ai
mesh_terms: D005506:Food Contamination / Q000032:analysis*; D018857:Food Packaging / Q000379:methods; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods*; D010968:Plasticizers / Q000032:analysis*; D011143:Polyvinyl Chloride / Q000737:chemistry*
chemical_list: D010968:Plasticizers; D011143:Polyvinyl Chloride