title: Preparation of functionalized organomanganese(II) reagents by direct insertion of manganese to aromatic and benzylic halides.
abstract: Functionalized arylmanganese compounds were prepared using commercial manganese powder in the presence of LiCl and catalytic amounts of both 2.5% InCl(3) and 2.5% PbCl(2) (THF, 0-50 °C). In addition, benzylic manganese reagents are obtained at 25 °C in ca. 70-80% yield (in the absence of LiCl) using commercial manganese powder and catalytic amounts of 2.5% InCl(3) and 2.5% PbCl(2). The resulting organomanganese reagents undergo smooth 1,2-addition, acylation, allylic substitution, Pd-catalyzed cross-coupling, and copper-catalyzed conjugate addition, affording the desired products in good yields.
authors.affiliation: Department Chemie, Ludwig-Maximilians-Universität München, Butenandtstrasse 5-13, Haus F, 81377 München, Germany.
authors.forename: Zhihua
authors.initials: Z
authors.lastname: Peng
authors.forename: Paul
authors.initials: P
authors.lastname: Knochel