title: [Clinical manifestation and diagnosis of non-Hodgkin's lymphoma (NHL) in head and neck : analysis of 138 cases].
abstract: OBJECTIVE
  To analyze the clinical features, pathological classification, causes of misdiagnosis, treatment and prognosis of non-Hodgkin's lymphoma (NHL) originated in head and neck and to afford experience in early diagnosis and treatment.
  
  
  METHODS
  The clinical manifestation , treatment and prognosis of 138 cases of primary head and neck NHL were studied retrospectively.
  
  
  RESULTS
  The incidence in male was higher than that in female (male:female=1.26:1). Among non-Hodgkin's lymphomas, 86.2% were neoplasms originating from B lymphocytes,which was remarkably higher than those originating from T lymphocyte(13.8%). The early symptom was mainly painless mass(71.7%). The primary location was in the following order: cervical region, submandibular region , parotid gland, skin of face, maxilla and mandible, tongue and palate. The main treatment was multimodal therapy(chemotherapy and operations).The five- year survival rate was 59.4%.
  
  
  CONCLUSIONS
  The clinical manifestation of head and neck NHL is not specific and has a high misdiagnosis rate,so we must pay more attention to improve the early diagnosis and treatment of NHL.
authors.affiliation: Department of Stomatology, PLA General Hospital, Beijing 100853, China. liuhuawei840222@126.com
authors.forename: Hua-wei
authors.initials: HW
authors.lastname: Liu
authors.forename: Wei-sheng
authors.initials: WS
authors.lastname: Wen
authors.forename: Ge
authors.initials: G
authors.lastname: Yang
mesh_terms: D003131:Combined Modality Therapy; D005260:Female; D006258:Head and Neck Neoplasms; D006801:Humans; D008228:Lymphoma, Non-Hodgkin; D008297:Male; D010306:Parotid Gland; D011379:Prognosis; D012189:Retrospective Studies; D015996:Survival Rate