title: Medical comorbidity of sleep disorders.
abstract: OBJECTIVE
  Recently published literature indicates that sleep disorders present with medical comorbidities quite frequently. The coexistence of a sleep disorder with a medical disorder has a substantial impact for both the patient and the health system.
  
  
  RESULTS
  Insomnia and hypersomnia are highly comorbid with medical conditions, such as chronic pain and diabetes, as well as with various cardiovascular, respiratory, gastrointestinal, urinary and neurological disorders. Restless legs syndrome and periodic leg movement syndrome have been associated with iron deficiency, kidney disease, diabetes, and neurological, autoimmune, cardiovascular and respiratory disorders. Rapid eye movement behaviour disorder has been described as an early manifestation of serious central nervous system diseases; thus, close neurological monitoring of patients referring with this complaint is indicated.
  
  
  CONCLUSIONS
  Identification and management of any sleep disorder in medical patients is important for optimizing the course and prognosis. Of equal importance is the search for undetected medical disorder in patients presenting with sleep disorders.
authors.affiliation: 1st Department of Psychiatry, Athens University Medical School, Athens, Greece. ddikeos@med.uoa.gr
authors.forename: Dimitris
authors.initials: D
authors.lastname: Dikeos
authors.forename: Georgios
authors.initials: G
authors.lastname: Georgantopoulos
mesh_terms: D002318:Cardiovascular Diseases / Q000453:epidemiology*; D015897:Comorbidity; D003920:Diabetes Mellitus / Q000453:epidemiology*; D006801:Humans; D010146:Pain / Q000453:epidemiology*; D012893:Sleep Wake Disorders / Q000453:epidemiology*