title: Experience with a frontal core biopsy device in soft tissue and bone lesions.
abstract: OBJECTIVE
  To assess the efficacy and cost of a new frontloading biopsy system, Spirotome® (system 1), in musculoskeletal lesions, and to compare the results with those obtained with commonly used biopsy devices.
  
  
  METHODS
  System 1 was used in all soft tissue lesions (STL) and osteolytic bone lesions (OBL) of patients who presented at our department for CT-guided biopsy between January 2009 and June 2010. Accuracy and cost were compared to those of Bonopty® (system 2) and Tru-cut (system 3) procedures.
  
  
  RESULTS
  The efficacy of system 1 was 85% in STL and 89% in OBL. The procedure was well tolerated and caused no complications. System 3 had an efficacy of 84% in STL and OBL combined. The efficacy of system 2 in OBL was 85%. The cost of single-use system 1 and system 2 was comparable, the cost of system 3 and multiuse system 1 compared to single-use system 1 was 25 and 7%, respectively.
  
  
  CONCLUSIONS
  The efficacy of system 1 in biopsy of STL and OBL was better than that of system 3. In OBL, the efficacy of system 1 was better than that of system 2. In STL at hazardous locations and small OBL with a thin cortical shell, system 1 offers the advantage of variable length and controlled loading. In these cases, single-use system 1 was cost-effective when compared to surgical biopsy. The cost per procedure of multiuse system 1 was lower than of system 3.
authors.affiliation: Department of Radiology, University of Antwerp and Antwerp University Hospital, Wilrijkstraat 10, 2650, Edegem, Belgium. jan.gielen@uza.be
authors.forename: Jan L
authors.initials: JL
authors.lastname: Gielen
authors.forename: Arthur M
authors.initials: AM
authors.lastname: De Schepper
authors.forename: Reinoud
authors.initials: R
authors.lastname: Blom
authors.forename: Pieter
authors.initials: P
authors.lastname: Van Dyck
authors.forename: Jan M L
authors.initials: JM
authors.lastname: Bosmans
authors.forename: David H
authors.initials: DH
authors.lastname: Creytens
authors.forename: Jan
authors.initials: J
authors.lastname: Veryser
authors.forename: Johan
authors.initials: J
authors.lastname: Somville
authors.forename: Paul M
authors.initials: PM
authors.lastname: Parizel
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001706:Biopsy / Q000191:economics / Q000295:instrumentation; D001707:Biopsy, Needle / Q000191:economics; D001847:Bone Diseases / Q000473:pathology*; D003362:Cost-Benefit Analysis; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012983:Soft Tissue Neoplasms / Q000473:pathology*; D014057:Tomography, X-Ray Computed; D055815:Young Adult