title: Orbital dissemination of Lemierre syndrome from gram-positive septic emboli.
abstract: A 45-year-old patient presented with bilateral orbital abscesses. He was found to have Lemierre syndrome, a condition involving septic thrombophlebitis of the internal jugular vein. The patient developed severe proptosis, sepsis, and cavernous sinus thrombosis. Despite aggressive antibiotic and anticoagulation therapy, visual loss was rapid, and the patient ultimately died. Lemierre syndrome, previously thought to be rare, is now becoming more commonly reported. Its prompt diagnosis and treatment are essential for patient survival.
authors.affiliation: Department of Ophthalmology, New York University School of Medicine, 462 First Avenue, NBV 5N-18, New York, NY 10016, U.S.A. jonathanbkahn@yahoo.com
authors.forename: Jonathan B
authors.initials: JB
authors.lastname: Kahn
authors.forename: Samuel
authors.initials: S
authors.lastname: Baharestani
authors.forename: Heather C
authors.initials: HC
authors.lastname: Beck
authors.forename: Diana
authors.initials: D
authors.lastname: Ng
authors.forename: Christopher I
authors.initials: CI
authors.lastname: Zoumalan
authors.forename: Floyd A
authors.initials: FA
authors.lastname: Warren
authors.forename: Richard N
authors.initials: RN
authors.lastname: Palu
mesh_terms: D000038:Abscess / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D016470:Bacteremia / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D020226:Cavernous Sinus Thrombosis / Q000175:diagnosis / Q000382:microbiology; D017809:Fatal Outcome; D006801:Humans; D057831:Lemierre Syndrome / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D054517:Orbital Cellulitis / Q000175:diagnosis / Q000382:microbiology; D009916:Orbital Diseases / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D013290:Streptococcal Infections / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D034364:Streptococcus milleri Group / Q000302:isolation & purification*; D014057:Tomography, X-Ray Computed