title: Atom arrangement strategy for designing a turn-on 1H magnetic resonance probe: a dual activatable probe for multimodal detection of hypochlorite.
abstract: The first dual activatable hypochlorite ((-)OCl)-sensing probe was developed, based on a new proof-of-concept design involving signal-activatable (1)H chemical probes using the triple-resonance NMR technique. The probe enabled fluorescence-(1)H MR dual turn-on detection of (-)OCl in solution and in crude tissue extracts.
authors.affiliation: INAMORI Frontier Research Center, Kyushu University, 744 Motooka, Fukuoka 819-0395, Japan.
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Doura
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Nonaka
authors.forename: Shinsuke
authors.initials: S
authors.lastname: Sando
mesh_terms: D003374:Coumarins / Q000138:chemical synthesis / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000138:chemical synthesis / Q000737:chemistry*; D006997:Hypochlorous Acid / Q000032:analysis*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D011522:Protons
chemical_list: D003374:Coumarins; D005456:Fluorescent Dyes; D011522:Protons; D006997:Hypochlorous Acid; C026308:3,4-dihydrocoumarin