title: [Rosai -Dorfman disease: a two cases report].
abstract: BACKGROUND
  Rosai-Dorfman disease (RDD) is a benign lymphoproliferatif disorder characterized by cervical lymphadenopathies with a consistent risk of airways' compression and esthetical prejudice. Extra nodal localizations are also described.
  
  
  OBJECTIVE
  To report two pediatric cases of RDD.
  
  
  METHODS
  the first case concerned a patient with a prolonged nodal involvement of RDD. Remission seems to be natural although it coincided with a sulfaméthoxazole- triméthoprime therapy. The second case illustrated an extranodal form of RDD localized in soft tissue and paranasal sinus with extension to nasal cavity which were corticodependant.
  
  
  CONCLUSIONS
  RDD is usually a benign disorder. Particular localizations, lack of effective therapy and the high risk of recurrence are important issues in this rare affection.
authors.affiliation: Hopital La Rabta, Tunis, Tunisie.
authors.forename: Hadhami
authors.initials: H
authors.lastname: Ben Turkia
authors.forename: Manal
authors.initials: M
authors.lastname: Ben Romdhane
authors.forename: Hatem
authors.initials: H
authors.lastname: Azzouz
authors.forename: Amel
authors.initials: A
authors.lastname: Ben Chehida
authors.forename: Mohamed Slim
authors.initials: MS
authors.lastname: Abdelmoula
authors.forename: Rim
authors.initials: R
authors.lastname: Ben Abdelaziz
authors.forename: Neji
authors.initials: N
authors.lastname: Tebib
authors.forename: Monia
authors.initials: M
authors.lastname: Ben Messoud
authors.forename: Samia
authors.initials: S
authors.lastname: Sahtout
authors.forename: Ines
authors.initials: I
authors.lastname: Chelly
authors.forename: Moncef
authors.initials: M
authors.lastname: Zitouni
authors.forename: Emna
authors.initials: E
authors.lastname: Mnif
authors.forename: Marie Francoise
authors.initials: MF
authors.lastname: Ben Dridi
mesh_terms: D002648:Child; D018450:Disease Progression; D015618:Histiocytosis, Sinus / Q000150:complications / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D006801:Humans; D055815:Young Adult