title: Gardner syndrome: presurgical planning and surgical management of craniomaxillofacial osteomas.
abstract: Gardner syndrome, a variant of familial adenomatous polyposis, is an autosomal dominant genetic disease characterized by the combined presence of multiple intestinal polyps and extraintestinal manifestations. The extraintestinal manifestations include multiple osteomas, connective tissue tumors, thyroid carcinomas, and hypertrophy of the pigmented epithelium of the retina. Osteoma is a benign neoplasm of bone tissue characterized by slow continuous growth that usually affects the long bones and cranial bones and is a major symptom for Gardner syndrome. The authors report the extraintestinal lesions affecting the maxillofacial regions in 2 male patients (father and son) with Gardner syndrome. The presurgical planning and surgical management of these lesions are described.
authors.affiliation: Department of Maxillo-Facial Surgery Azienda Ospedaliera Maggiore della Carità University of Piemonte Orientale Amedeo Avogadro, Novara, Italy.
authors.forename: Matteo
authors.initials: M
authors.lastname: Brucoli
authors.forename: Mariangela
authors.initials: M
authors.lastname: Giarda
authors.forename: Arnaldo
authors.initials: A
authors.lastname: Benech
mesh_terms: D000328:Adult; D005736:Gardner Syndrome / Q000000981:diagnostic imaging / Q000601:surgery*; D006801:Humans; D008297:Male; D008339:Mandibular Neoplasms / Q000000981:diagnostic imaging / Q000601:surgery*; D008875:Middle Aged; D010016:Osteoma / Q000000981:diagnostic imaging / Q000601:surgery*; D010027:Osteotomy / Q000379:methods; D010347:Patient Care Planning; D011862:Radiography, Panoramic; D014057:Tomography, X-Ray Computed