title: One-dimensional magnetic nanowires obtained by protein fibril biotemplating.
abstract: Magnetic nanowires were obtained through the in situ synthesis of magnetic material by Fe-controlled nanoprecipitation in the presence of two different protein (human serum albumin (HSA) and lysozyme (Lys)) fibrils as biotemplating agents. The structural characteristics of the biotemplates were transferred to the hybrid magnetic wires. They exhibited excellent magnetic properties as a consequence of the 1D assembly and fusion of magnetite nanoparticles as ascertained by SQUID magnetometry. Prompted by these findings, we also checked their potential applicability as MRI contrast agents. The magnetic wires exhibited large r(2)* relaxivities and sufficient contrast resolution even in the presence of an extremely small amount of Fe in the magnetic hybrids, which would potentially enable their use as T(2) contrast imaging agents.
authors.affiliation: Grupo de Física de Coloides y Polímeros, Departamento de Física de la Materia Condensada, Facultad de Física, Universidad de Santiago de Compostela, 15782 Santiago de Compostela, Spain.
authors.forename: Josué
authors.initials: J
authors.lastname: Juárez
authors.forename: Adriana
authors.initials: A
authors.lastname: Cambón
authors.forename: Antonio
authors.initials: A
authors.lastname: Topete
authors.forename: Pablo
authors.initials: P
authors.lastname: Taboada
authors.forename: Víctor
authors.initials: V
authors.lastname: Mosquera
mesh_terms: D000465:Algorithms; D003287:Contrast Media / Q000737:chemistry*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008280:Magnetics; D009113:Muramidase / Q000737:chemistry; D053770:Nanowires / Q000737:chemistry*; D011506:Proteins / Q000737:chemistry* / Q000648:ultrastructure; D012709:Serum Albumin / Q000737:chemistry
chemical_list: D003287:Contrast Media; D011506:Proteins; D012709:Serum Albumin; D009113:Muramidase