title: Oral inflammatory myofibroblastic tumor: case report and review of literature.
abstract: Inflammatory myofibroblastic tumor (IMT) is a rarely described tumor of unknown etiology and pathogenesis. It occurs primarily in the lungs, but has occurred in other extra-pulmonary sites. Histologically these lesions appear as an inflammatory infiltrate within a variably myofibrotic background. Current evidence shows that inflammatory myofibroblastic tumors are neoplastic processes resulting from chromosomal translocations that often cause an overexpression of ALK kinase, which is often assessed using immunohistochemical studies. Currently, the biological behavior of oral inflammatory myofibroblastic tumor is still uncertain. This article describes the clinical, histological, and operative features of a case of IMT of the oral cavity.
authors.affiliation: Department of Oncology and Diagnostic Sciences, Dental School, University of Maryland, Baltimore, USA.
authors.forename: Nada O
authors.initials: NO
authors.lastname: Binmadi
authors.forename: Harold
authors.initials: H
authors.lastname: Packman
authors.forename: John C
authors.initials: JC
authors.lastname: Papadimitriou
authors.forename: Mark
authors.initials: M
authors.lastname: Scheper