title: First-bite syndrome complicating carotid endarterectomy: a case report and literature review.
abstract: First-bite syndrome (FBS) is an infrequently encountered complication of parapharyngeal space surgery. Patients experience excruciating pain in the ipsiltateral parotid gland region at the first bite of each meal, which improves with subsequent mastication. This is thought to be due to parotid gland sympathetic denervation from surgery with resultant hypersensitivity to parasympathetic impulses. There is no consensus on best treatment for FBS although symptoms tend to improve with time. There are only 2 case reports linking carotid endarterectomy and FBS so far. We report the third case of FBS after carotid endarterectomy to raise awareness among vascular surgeons of the possibility of this complication.
authors.affiliation: Department of Vascular Surgery, Gloucestershire Royal Hospital, Great Western Road, Gloucester, UK.
authors.forename: Eugene H C
authors.initials: EH
authors.lastname: Wong
authors.forename: Jerry N
authors.initials: JN
authors.lastname: Farrier
authors.forename: David G
authors.initials: DG
authors.lastname: Cooper
mesh_terms: D000369:Aged, 80 and over; D016894:Endarterectomy, Carotid / Q000009:adverse effects*; D005156:Facial Neuralgia / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology; D006801:Humans; D008297:Male; D008409:Mastication; D010147:Pain Measurement; D010149:Postoperative Pain / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology; D010275:Parasympathetic Nervous System / Q000503:physiopathology*; D010306:Parotid Gland / Q000294:innervation*; D013564:Sympathetic Nervous System / Q000293:injuries* / Q000503:physiopathology