title: Mitotic moonlighting functions for membrane trafficking proteins.
abstract: In recent years, cell biologists have uncovered a number of new functions for proteins that were previously thought to operate solely in membrane trafficking. These alternative roles, termed moonlighting functions, can occur at distinct intracellular sites or at different stages of the cell cycle. Here, I evaluate the evidence for mitotic moonlighting functions of proteins that have membrane trafficking roles during interphase. The aim is to identify key issues facing the field and to outline important questions for future work.
authors.affiliation: Physiological Laboratory, University of Liverpool, Crown Street, Liverpool L69 3BX, UK. s.j.royle@liverpool.ac.uk
authors.forename: Stephen J
authors.initials: SJ
authors.lastname: Royle
mesh_terms: D048868:Adaptor Proteins, Signal Transducing / Q000378:metabolism; D033942:Adaptor Proteins, Vesicular Transport / Q000378:metabolism; D000818:Animals; D002460:Cell Line; D002966:Clathrin / Q000378:metabolism; D034281:Dynamins / Q000378:metabolism; D007399:Interphase / Q000502:physiology; D026901:Membrane Transport Proteins / Q000378:metabolism*; D008938:Mitosis / Q000502:physiology*; D017346:Protein Serine-Threonine Kinases / Q000378:metabolism; D021381:Protein Transport / Q000502:physiology; D014404:Tubulin / Q000378:metabolism
chemical_list: D048868:Adaptor Proteins, Signal Transducing; D033942:Adaptor Proteins, Vesicular Transport; D002966:Clathrin; D026901:Membrane Transport Proteins; D014404:Tubulin; C114154:epsin; D017346:Protein Serine-Threonine Kinases; D034281:Dynamins