title: In vitro interaction between fluconazole and triclosan against clinical isolates of fluconazole-resistant Candida albicans determined by different methods.
abstract: The in vitro interaction between triclosan and fluconazole against 24 azole-resistant clinical isolates of Candida albicans was evaluated by the microdilution checkerboard technique. The synergisms were verified by time-killing curves and agar diffusion tests in selected strains. Antagonistic activity was not detected.
authors.affiliation: Laboratory of Nutrition and Functional Food, Jilin University, Changchun, China.
authors.forename: Lu
authors.initials: L
authors.lastname: Yu
authors.forename: Guanghui
authors.initials: G
authors.lastname: Ling
authors.forename: Xuming
authors.initials: X
authors.lastname: Deng
authors.forename: Jing
authors.initials: J
authors.lastname: Jin
authors.forename: Qi
authors.initials: Q
authors.lastname: Jin
authors.forename: Na
authors.initials: N
authors.lastname: Guo
mesh_terms: D002176:Candida albicans / Q000187:drug effects*; D004347:Drug Interactions; D025141:Drug Resistance, Fungal; D015725:Fluconazole / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests; D014260:Triclosan / Q000494:pharmacology*
chemical_list: D014260:Triclosan; D015725:Fluconazole