title: Neurocognition and occupational functioning in patients with first-episode psychosis: a 2-year follow-up study.
abstract: Neurocognitive deficits are a core feature of schizophrenia that is associated with poor occupational functioning. Few studies have investigated this relationship in patients with first-episode psychosis. The current study examined the characteristics of employed and unemployed patients with first-episode psychosis at baseline and 2-year follow-up, and the predictive value of neurocognition on employment status. One-hundred and twenty-two first-episode psychosis patients were assessed with clinical and neurocognitive measures at baseline. Occupational status was assessed at baseline and 2-year follow-up. Those unemployed at baseline were rated lower on global functioning and were more likely to have a schizophrenia spectrum disorder. Total employment rates were 41% at baseline and 38% at 2-year follow-up. Four employment paths emerged at follow-up, defined as persistently employed, becoming unemployed, entering employment and persistently unemployed. The persistently employed group had the highest global functioning score. For the total sample, baseline employment status and sustained attention predicted employment status at follow-up. For those employed at baseline, better sustained attention, higher global functioning, more positive symptoms and less alcohol use predicted persistent employment at follow-up. For those unemployed at baseline, none of the variables predicted change in employment status. Implications of these results are discussed.
authors.affiliation: Division of Mental Health and Addiction, Oslo University Hospital, 0407 Oslo, Norway. martetan@student.sv.uio.no
authors.forename: Marte
authors.initials: M
authors.lastname: Tandberg
authors.forename: Torill
authors.initials: T
authors.lastname: Ueland
authors.forename: Kjetil
authors.initials: K
authors.lastname: Sundet
authors.forename: Ulrik
authors.initials: U
authors.lastname: Haahr
authors.forename: Inge
authors.initials: I
authors.lastname: Joa
authors.forename: Jan Olav
authors.initials: JO
authors.lastname: Johannessen
authors.forename: Tor Ketil
authors.initials: TK
authors.lastname: Larsen
authors.forename: Stein
authors.initials: S
authors.lastname: Opjordsmoen
authors.forename: Bjørn Rishovd
authors.initials: BR
authors.lastname: Rund
authors.forename: Jan Ivar
authors.initials: JI
authors.lastname: Røssberg
authors.forename: Erik
authors.initials: E
authors.lastname: Simonsen
authors.forename: Per
authors.initials: P
authors.lastname: Vaglum
authors.forename: Ingrid
authors.initials: I
authors.lastname: Melle
authors.forename: Svein
authors.initials: S
authors.lastname: Friis
authors.forename: Thomas
authors.initials: T
authors.lastname: McGlashan
mesh_terms: D000328:Adult; D000368:Aged; D003072:Cognition Disorders / Q000175:diagnosis* / Q000209:etiology*; D004651:Employment; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D001523:Mental Disorders / Q000150:complications* / Q000523:psychology*; D008875:Middle Aged; D015999:Multivariate Analysis; D009483:Neuropsychological Tests; D011569:Psychiatric Status Rating Scales; D011597:Psychomotor Performance; D012720:Severity of Illness Index; D018709:Statistics, Nonparametric; D014706:Verbal Learning