title: Localized oropharyngeal amyloidosis.
abstract: An otherwise healthy 29-year-old woman presented with a complaint of odynophagia of several months' duration. On examination, she was found to have a broadly based, yellow, exophytic lesion on the right lateral pharyngeal wall. Findings on biopsy were consistent with amyloidosis. The patient underwent tonsillectomy with resection of the oropharyngeal lesion. Final pathology established a diagnosis of nodular non-AL-type amyloidosis. Localized amyloidosis of the oropharynx is exceptionally rare. Additionally, most cases of localized amyloidosis are of the AL type, not the AA (i.e., non-AL) type seen in this patient.
authors.affiliation: Division of Otolaryngology, Nemours/Alfred I. duPont Hospital for Children, Wilmington, DE 19803, USA. cgrindle@nemours.org
authors.forename: Christopher R
authors.initials: CR
authors.lastname: Grindle
authors.forename: Joseph M
authors.initials: JM
authors.lastname: Curry
authors.forename: Joshua P
authors.initials: JP
authors.lastname: Cantor
authors.forename: Kelly M
authors.initials: KM
authors.lastname: Malloy
authors.forename: Edmund A
authors.initials: EA
authors.lastname: Pribitkin
authors.forename: William M
authors.initials: WM
authors.lastname: Keane
mesh_terms: D000328:Adult; D000686:Amyloidosis / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D003680:Deglutition Disorders / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D009960:Oropharynx / Q000473:pathology* / Q000601:surgery; D014068:Tonsillectomy / Q000295:instrumentation / Q000379:methods*