title: Synergistic antibacterial brilliant blue/reduced graphene oxide/quaternary phosphonium salt composite with excellent water solubility and specific targeting capability.
abstract: A water-soluble brilliant blue/reduced graphene oxide/tetradecyltriphenylphosphonium bromide composite (BB-rGO-TTP) was prepared by using noncovalent brilliant blue-functionalized reduced graphene oxide (BB-rGO) as the tetradecyltriphenylphosphonium bromide (TTP) carrier. Antibacterial performance of this novel composite was investigated for both Gram-positive and Gram-negative bacteria. The results showed that the novel BB-rGO-TTP, combing the advantages of graphene and TTP, displayed excellent synergistic antibacterial activity, specific targeting capability, water solubility, and mild cytotoxicity, suggesting the great potential application as sprayable graphene-based antibacterial solutions.
authors.affiliation: Department of Chemistry, Jinan University, Guangzhou 510632, China.
authors.forename: Xiang
authors.initials: X
authors.lastname: Cai
authors.forename: Shaozao
authors.initials: S
authors.lastname: Tan
authors.forename: Minsong
authors.initials: M
authors.lastname: Lin
authors.forename: Agui
authors.initials: A
authors.lastname: Xie
authors.forename: Wenjie
authors.initials: W
authors.lastname: Mai
authors.forename: Xiuju
authors.initials: X
authors.lastname: Zhang
authors.forename: Zhidan
authors.initials: Z
authors.lastname: Lin
authors.forename: Ting
authors.initials: T
authors.lastname: Wu
authors.forename: Yingliang
authors.initials: Y
authors.lastname: Liu
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry*; D001557:Benzenesulfonates / Q000737:chemistry*; D006108:Graphite / Q000737:chemistry*; D063065:Organophosphonates / Q000737:chemistry*; D012995:Solubility; D014867:Water
chemical_list: D000900:Anti-Bacterial Agents; D001557:Benzenesulfonates; D063065:Organophosphonates; D014867:Water; D006108:Graphite; C006796:brilliant blue