title: Steviamine, a new class of indolizidine alkaloid [(1R,2S,3R,5R,8aR)-3-hydroxy-meth-yl-5-methyl-octa-hydro-indolizine-1,2-diol hydro-bromide].
abstract: X-ray crystallographic analysis of the title hydro-bromide salt, C(10)H(20)N(+)·Br(-), of (1R,2S,3R,5R,8aR)-3-hydroxy-meth-yl-5-methyl-octa-hydro-indolizine-1,2-diol defines the absolute and relative stereochemistry at the five chiral centres in steviamine, a new class of polyhydroxy-lated indolizidine alkaloid isolated from Stevia rebaudiana (Asteraceae) leaves. In the crystal structure, mol-ecules are linked by inter-molecular O-H⋯Br and N-H⋯Br hydrogen bonds, forming double chains around the twofold screw axes along the b-axis direction. Intra-molecular O-H⋯O inter-actions occur.
authors.forename: Amber L
authors.initials: AL
authors.lastname: Thompson
authors.forename: Agnieszka
authors.initials: A
authors.lastname: Michalik
authors.forename: Robert J
authors.initials: RJ
authors.lastname: Nash
authors.forename: Francis X
authors.initials: FX
authors.lastname: Wilson
authors.forename: Renate
authors.initials: R
authors.lastname: van Well
authors.forename: Peter
authors.initials: P
authors.lastname: Johnson
authors.forename: George W J
authors.initials: GW
authors.lastname: Fleet
authors.forename: Chu-Yi
authors.initials: CY
authors.lastname: Yu
authors.forename: Xiang-Guo
authors.initials: XG
authors.lastname: Hu
authors.forename: Richard I
authors.initials: RI
authors.lastname: Cooper
authors.forename: David J
authors.initials: DJ
authors.lastname: Watkin