title: A case of high-level metronidazole-resistant trichomoniasis in pregnancy successfully treated.
abstract: The incidence of metronidazole-resistant trichomoniasis is approximately 5%. Resistance during pregnancy has not been reported. Untreated trichomoniasis in pregnancy can cause preterm labor, premature rupture of membranes, and low birth weight. We report a case of metronidazole-resistant trichomoniasis in pregnancy, successfully treated with a high dose of tinidazole.
authors.affiliation: Division of Infectious Diseases, Wayne State University, Detroit, MI, USA. chi77subra@yahoo.co.in
authors.forename: Chithra
authors.initials: C
authors.lastname: Subramanian
authors.forename: Jack D
authors.initials: JD
authors.lastname: Sobel
mesh_terms: D000328:Adult; D000890:Anti-Infective Agents / Q000627:therapeutic use*; D000994:Antitrichomonal Agents / Q000627:therapeutic use; D004352:Drug Resistance, Microbial; D005260:Female; D006801:Humans; D008795:Metronidazole / Q000627:therapeutic use*; D011247:Pregnancy; D015597:Pregnancy Complications, Parasitic / Q000188:drug therapy*; D014011:Tinidazole / Q000627:therapeutic use*; D016896:Treatment Outcome; D014245:Trichomonas Infections / Q000188:drug therapy*
chemical_list: D000890:Anti-Infective Agents; D000994:Antitrichomonal Agents; D014011:Tinidazole; D008795:Metronidazole