title: Follicular bronchiolitis in a child.
abstract: BACKGROUND
  Follicular bronchiolitis (FB) is an uncommon but important pulmonary manifestation in children.
  
  
  METHODS
  In this report, we present the clinical presentations and histopathological data of an 8-year-old boy with FB.
  
  
  RESULTS
  The patient had a history of recurrent cough and dyspnea for 5 years with progressive worsening of symptoms. An initial pulmonary function test showed an obstructive ventilatory defect. Chest X-ray demonstrated miliary nodules. High-resolution computed tomography showed reticulonodular opacification and central consolidation. Histopathological examination revealed that lymphoid follicles with reactive germinal centers distributed along the bronchioles. The boy responded favorably to corticosteroid therapy and recovered well.
  
  
  CONCLUSIONS
  Diagnosis of FB should be considered when a child presents with chronic bronchial obstruction. Open lung biopsy is necessary for confirmation of the diagnosis.
authors.affiliation: Department of Nephrology, Children's Hospital of Zhejiang University School of Medicine, Hangzhou 310003, China.
authors.forename: Yu-Wen
authors.initials: YW
authors.lastname: Dai
authors.forename: Long
authors.initials: L
authors.lastname: Lin
authors.forename: Hong-Feng
authors.initials: HF
authors.lastname: Tang
authors.forename: Ke-Wen
authors.initials: KW
authors.lastname: Jiang
mesh_terms: D001706:Biopsy; D001988:Bronchiolitis / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D002648:Child; D003371:Cough / Q000209:etiology; D020566:Dendritic Cells, Follicular / Q000473:pathology; D018450:Disease Progression; D004417:Dyspnea / Q000209:etiology; D018858:Germinal Center / Q000473:pathology; D006801:Humans; D006965:Hyperplasia; D008168:Lung / Q000473:pathology; D008221:Lymphoid Tissue / Q000473:pathology*; D008297:Male; D014057:Tomography, X-Ray Computed