title: Prasugrel, a new medicine for preventing blockages in the arteries.
abstract: Prasugrel {systematic name: 5-[(2-cyclo-propyl-carbon-yl)(2-fluoro-phen-yl)meth-yl]-4,5,6,7-tetra-hydro-thieno[3,2-c]pyridin-2-yl acetate}, C(20)H(20)FNO(3)S, is a new third-generation thienopyridine which was recently approved for clinical use as a more potent blocker of the platelet P2Y(12) receptor than clopidogrel, which was previously used for this purpose. The mol-ecule features a tetra-hydro-thienopyridine system with the tetra-hydro-pyridine ring showing a half-chair conformation; the dihedral angle formed by the the planes of the benzene and thio-phene rings is 83.17 (3)°.
authors.affiliation: School of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189, People's Republic of China.
authors.forename: Zhi-Mei
authors.initials: ZM
authors.lastname: Wang
authors.forename: Jian
authors.initials: J
authors.lastname: Zhao
authors.forename: Gang
authors.initials: G
authors.lastname: Xu