title: Unsuspected diversity of arsenite-oxidizing bacteria as revealed by widespread distribution of the aoxB gene in prokaryotes.
abstract: In this study, new strains were isolated from an environment with elevated arsenic levels, Sainte-Marie-aux-Mines (France), and the diversity of aoxB genes encoding the arsenite oxidase large subunit was investigated. The distribution of bacterial aoxB genes is wider than what was previously thought. AoxB subfamilies characterized by specific signatures were identified. An exhaustive analysis of AoxB sequences from this study and from public databases shows that horizontal gene transfer has likely played a role in the spreading of aoxB in prokaryotic communities.
authors.affiliation: Laboratoire de Génétique Moléculaire, Génomique, Microbiologie, Département Microorganismes, Génomes, Environnement, UMR7156 Université de Strasbourg/CNRS, 28 Rue Goethe, 67083 Strasbourg Cedex, France.
authors.forename: Audrey
authors.initials: A
authors.lastname: Heinrich-Salmeron
authors.forename: Audrey
authors.initials: A
authors.lastname: Cordi
authors.forename: Céline
authors.initials: C
authors.lastname: Brochier-Armanet
authors.forename: David
authors.initials: D
authors.lastname: Halter
authors.forename: Christophe
authors.initials: C
authors.lastname: Pagnout
authors.forename: Elham
authors.initials: E
authors.lastname: Abbaszadeh-fard
authors.forename: Didier
authors.initials: D
authors.lastname: Montaut
authors.forename: Fabienne
authors.initials: F
authors.lastname: Seby
authors.forename: Philippe N
authors.initials: PN
authors.lastname: Bertin
authors.forename: Pascale
authors.initials: P
authors.lastname: Bauda
authors.forename: Florence
authors.initials: F
authors.lastname: Arsène-Ploetze
mesh_terms: D001105:Archaea / Q000201:enzymology* / Q000235:genetics / Q000302:isolation & purification / Q000378:metabolism*; D018053:Arsenites / Q000378:metabolism*; D001419:Bacteria / Q000201:enzymology* / Q000235:genetics / Q000302:isolation & purification / Q000378:metabolism*; D016000:Cluster Analysis; D019641:DNA, Archaeal / Q000737:chemistry / Q000235:genetics; D004269:DNA, Bacterial / Q000737:chemistry / Q000235:genetics; D004783:Environmental Microbiology; D005602:France; D008969:Molecular Sequence Data; D010084:Oxidation-Reduction; D010088:Oxidoreductases / Q000235:genetics*; D010802:Phylogeny; D017422:Sequence Analysis, DNA; D017385:Sequence Homology
chemical_list: D018053:Arsenites; D019641:DNA, Archaeal; D004269:DNA, Bacterial; D010088:Oxidoreductases; C078179:arsenite oxidase; C015001:arsenite