title: Enantiocontrolled total syntheses of breviones A, B, and C.
abstract: Enantiocontrolled total syntheses of the breviones A, B, and C have been accomplished using a highly diastereoselective oxidative coupling of an α-pyrone with a tricyclic diene prepared from an optically pure Wieland-Miescher ketone derivative through the 7-endo-trig mode of acyl radical cyclization.
authors.affiliation: Graduate School of Pharmaceutical Sciences, The University of Tokushima, 1-78-1 Sho-machi, Tokushima 770-8505, Japan.
authors.forename: Hiromasa
authors.initials: H
authors.lastname: Yokoe
authors.forename: Chika
authors.initials: C
authors.lastname: Mitsuhashi
authors.forename: Yoko
authors.initials: Y
authors.lastname: Matsuoka
authors.forename: Tomoyuki
authors.initials: T
authors.lastname: Yoshimura
authors.forename: Masahiro
authors.initials: M
authors.lastname: Yoshida
authors.forename: Kozo
authors.initials: K
authors.lastname: Shishido
mesh_terms: D003500:Cyclization; D004224:Diterpenes / Q000138:chemical synthesis* / Q000737:chemistry*; D011083:Polycyclic Compounds / Q000138:chemical synthesis* / Q000737:chemistry*; D011753:Pyrones / Q000138:chemical synthesis* / Q000737:chemistry*; D013141:Spiro Compounds / Q000138:chemical synthesis* / Q000737:chemistry*; D013237:Stereoisomerism; D013379:Substrate Specificity
chemical_list: D004224:Diterpenes; D011083:Polycyclic Compounds; D011753:Pyrones; D013141:Spiro Compounds; C447979:brevione A; C512924:brevione B