title: Efficacy of octyl-2-cyanoacrylate in type I tympanoplasty.
abstract: OBJECTIVE
  To evaluate the safety and efficacy of octyl-2-cyanoacrylate for type I tympanoplasty.
  
  
  METHODS
  This study involved 23 patients (14 females and 9 males) with chronic otitis media who underwent type I tympanoplasty. During surgery, the temporal fascia is placed underlying the eardrum remnant, and octyl-2-cyanoacrylate was dropped over the temporal fascia. The mean air-bone gap (ABG) at the 4 frequencies (500, 1000, 2000, and 4000) was calculated for each patient before and after surgery. These data were compared by Student t test.
  
  
  RESULTS
  The mean follow-up was 10 months (range, 6-12 mo). Successful tympanic membrane grafting occurred in 21 patients (91.3%). Graft failure was seen in 2 patients. The mean preoperative ABG of the 23 patients was 19.3 (SD, 5.7) dB, and the postoperative ABG improved to a mean value of 8.2 (SD, 5.9) dB (P ≤ 0.0001).
  
  
  CONCLUSIONS
  Octyl-2-cyanoacrylate is effective and safe in using as a compound on temporalis muscle fascia in type I tympanoplasty and can be used more widely in tympanoplasty.
authors.affiliation: Kirklareli University Health College, Kirklareli, Turkey.
authors.forename: Orhan
authors.initials: O
authors.lastname: Gedikli
authors.forename: Sabri Baki
authors.initials: SB
authors.lastname: Eren
authors.forename: Volkan
authors.initials: V
authors.lastname: Kahya
authors.forename: Arzu Yasemin
authors.initials: AY
authors.lastname: Korkut
authors.forename: Aysenur Meric
authors.initials: AM
authors.lastname: Teker
authors.forename: Berna Uslu
authors.initials: BU
authors.lastname: Coskun
mesh_terms: D000328:Adult; D002908:Chronic Disease; D003487:Cyanoacrylates / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010033:Otitis Media / Q000601:surgery*; D038781:Otoscopy; D014014:Tissue Adhesives / Q000627:therapeutic use*; D016896:Treatment Outcome; D014433:Tympanoplasty / Q000379:methods*
chemical_list: D003487:Cyanoacrylates; D014014:Tissue Adhesives; C100832:octyl 2-cyanoacrylate