title: [Evaluation on left ventricular function by non-invasive transient deceleration wave intensity (W2) of carotid artery].
abstract: OBJECTIVE
  To evaluate transient deceleration wave intensity (W2) of carotid artery on left ventricular diastolic function.
  
  
  METHODS
  40 patients with hypertension and 43 healthy volunteers were enrolled and W2 of carotid artery of the both sides were measured. The parameters of left ventricular diastolic function by traditional and tissue Doppler imaging and NT-proBNP (N-terminal probrain natriuretic peptide) were measured.
  
  
  RESULTS
  (1) W2 is not different between two sides of carotid artery. W2 in hypertension was lower than the control, especially in left side(1126 +/- 996 mmHg x m/s3 vs 1690 +/- 1126 mmHg x m/s3, P < 0.01). (2) The correlation of W2 and else parameters were analyzed. There were notably decreasing in left ventricular diastolic function of the hypertensive group than the control, for example, the ratio of peak velocity of early filling of mitral flow to peak early diastolic motion velocity of mitral annulus (E/Em, 9.37 +/- 3.32 vs 7.39 +/- 1.83, P < 0.01) and NT-proBNP (94.6 +/- 48.5 vs 45.2 +/- 13.8, P < 0.01). (3) The correlation analysis showed negative relation between W2 and E/Em (r = - 0.46, P < 0.05) and negative relation between W2 and NT-proBNP (r = -0.21, P < 0.05).
  
  
  CONCLUSIONS
  New carotid W2 by non-invasive technology for hemodynamics is a deserving parameter in early evaluating left ventricular diastolic function.
authors.affiliation: Department 2 of Gerontic Cardiology, PLA General Hospital, Beijing 100853, China.
authors.forename: Dong-Mei
authors.initials: DM
authors.lastname: Miao
authors.forename: Ping
authors.initials: P
authors.lastname: Ye
authors.forename: Jin-Yao
authors.initials: JY
authors.lastname: Zhang
authors.forename: Peng
authors.initials: P
authors.lastname: Gao
authors.forename: Wen-Kai
authors.initials: WK
authors.lastname: Xiao
mesh_terms: D000328:Adult; D017536:Carotid Artery, Common / Q000503:physiopathology*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D020097:Natriuretic Peptide, Brain / Q000097:blood; D010446:Peptide Fragments / Q000097:blood; D018487:Ventricular Dysfunction, Left / Q000175:diagnosis / Q000503:physiopathology*; D016277:Ventricular Function, Left
chemical_list: D010446:Peptide Fragments; C109794:pro-brain natriuretic peptide (1-76); D020097:Natriuretic Peptide, Brain