title: Molecularly imprinted nanospheres by nonaqueous emulsion polymerization.
abstract: The preparation of nanosized, molecularly imprinted polymer particles by nonaqueous emulsion polymerization is presented. Monodisperse cross-linked polymer nanospheres with a diameter of around 100 nm were synthesized using a standard monomer mixture of methacrylic acid and ethylene dimethacrylate, containing (±)-propranolol as a template. The rebinding efficiency of the resulting particles was determined by batch rebinding tests and isothermal titration calorimetry (ITC). The results indicate that the proposed imprinting process under nonaqueous conditions lead to particles with an enhanced capacity of template rebinding compared to both nonimprinted ones and to particles obtained by more conventional emulsion polymerization in water.
authors.affiliation: Dipartimento di Scienze Chimiche, Università di Padova, via Marzolo 1, 35131 Padova, Italy.
authors.forename: Gita
authors.initials: G
authors.lastname: Dvorakova
authors.forename: Robert
authors.initials: R
authors.lastname: Haschick
authors.forename: Khalid
authors.initials: K
authors.lastname: Chiad
authors.forename: Markus
authors.initials: M
authors.lastname: Klapper
authors.forename: Klaus
authors.initials: K
authors.lastname: Müllen
authors.forename: Andrea
authors.initials: A
authors.lastname: Biffis