title: Radiological and clinical features of subcutaneous panniculitis-like T-cell lymphoma.
abstract: OBJECTIVE
  To retrospectively analyze computed tomography (CT) and clinical findings of patients with subcutaneous panniculitis-like T-cell lymphoma (SPTCL).
  
  
  METHODS
  The CT findings were retrospectively assessed in 8 patients (6 men, 2 women; age range, 23-60 years; mean age, 39.8 years) with pathologically proven SPTCL. The tumor location, number, distribution, size, and morphological characteristics on CT were evaluated, as were maximum standardized uptake values on positron emission tomography. We also evaluated patient symptoms, laboratory findings, immunophenotype, involvement of bone marrow, treatment, and outcomes.
  
  
  RESULTS
  All 8 patients had multiple (range, 4 to numerous) soft tissue lesions involving subcutaneous fat tissue of the chest, abdominal wall, back, and buttock. Lesions varied in size (range, 0.5-10 cm) and showed reticular (n = 1), nodular (n = 4), and diffuse infiltrative (n = 3) patterns. Three patients had lesions involving the entire thickness of fat tissue, 3 had partial lesions, and 2 had variable lesions. Skin thickening was mild in 4 patients, moderate in 2, and severe in 2; fascia thickening was mild in 3 patients, moderate in one, severe in one, and variable in 2. In 7 patients, lesions were accompanied by engorged supplying vessels. At onset, maximum standardized uptake values varied from 1.2 to 4.7, decreasing to 0.0 to 4.2. Five patients had αβ type and one had γδ type. Clinical outcome varied: two remain alive with disease, two had no disease, and one died.
  
  
  CONCLUSIONS
  The SPTCL is characterized by multiple, nodular, or diffuse soft tissue lesions involving subcutaneous fat tissue, accompanied by engorged vessels and skin and fascial thickening. Patients vary in presentation and in treatment outcomes.
authors.affiliation: Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
authors.forename: Jong Woo
authors.initials: JW
authors.lastname: Kim
authors.forename: Eun Jin
authors.initials: EJ
authors.lastname: Chae
authors.forename: Young Soo
authors.initials: YS
authors.lastname: Park
authors.forename: Hyun Joo
authors.initials: HJ
authors.lastname: Lee
authors.forename: Hye Jeon
authors.initials: HJ
authors.lastname: Hwang
authors.forename: Chaehun
authors.initials: C
authors.lastname: Lim
authors.forename: Hye Won
authors.initials: HW
authors.lastname: Chung
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D016399:Lymphoma, T-Cell / Q000000981:diagnostic imaging / Q000401:mortality / Q000473:pathology; D008297:Male; D008875:Middle Aged; D015434:Panniculitis / Q000000981:diagnostic imaging / Q000401:mortality / Q000473:pathology; D011877:Radionuclide Imaging; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed / Q000379:methods*; D051598:Whole Body Imaging