title: New and innovative interventions in the management of pemphigus.
abstract: Pemphigus is a rare autoimmune blistering disease usually treated with systemic glucocorticoids with adjuvant immunosuppressants or anti-inflammatories. However significant morbidity and mortality is associated with these treatments. This review discusses conventional therapeutic options, as well as new and emerging therapies that may be safer alternatives to broad-based immunosuppression.
authors.affiliation: Department of Dermatology, The University of Iowa, IA, USA.
authors.forename: A S
authors.initials: AS
authors.lastname: Frydman
authors.forename: J A
authors.initials: JA
authors.lastname: Fairley
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D003879:Dermatologic Agents / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007155:Immunologic Factors / Q000627:therapeutic use; D007163:Immunosorbent Techniques; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D010392:Pemphigus / Q000188:drug therapy / Q000628:therapy*; D017893:Photopheresis; D010956:Plasmapheresis; D016032:Randomized Controlled Trials as Topic; D012307:Risk Factors
chemical_list: D000900:Anti-Bacterial Agents; D000893:Anti-Inflammatory Agents; D003879:Dermatologic Agents; D005938:Glucocorticoids; D007155:Immunologic Factors; D007166:Immunosuppressive Agents