title: Performance of the BioPlex 2200 multiplexing immunoassay platform for the detection of herpes simplex virus type 2 specific antibodies in African settings.
abstract: The BioPlex platform was evaluated for the detection of herpes simplex virus 2 (HSV-2) antibodies in sub-Saharan Africa individuals in comparison to clinicovirological standards and compared to HerpeSelect. The sensitivities and specificities were, respectively, 88.9% and 93.5% for BioPlex and 89.9% and 92.7% for HerpeSelect. The agreement between both assays was 95.7%.
authors.affiliation: Université Paris Diderot, Sorbonne Paris Cité, Inserm U941, and Laboratoire de Virologie, Hôpital Saint-Louis, APHP, Paris, France. jerome.le-goff@sls.aphp.fr
authors.forename: Jérôme
authors.initials: J
authors.lastname: LeGoff
authors.forename: Gérard
authors.initials: G
authors.lastname: Grésenguet
authors.forename: Chrysostome
authors.initials: C
authors.lastname: Gody
authors.forename: Jean De Dieu
authors.initials: Jde D
authors.lastname: Longo
authors.forename: Nzambi
authors.initials: N
authors.lastname: Khonde
authors.forename: Helen A
authors.initials: HA
authors.lastname: Weiss
authors.forename: Philippe
authors.initials: P
authors.lastname: Mayaud
authors.forename: Laurent
authors.initials: L
authors.lastname: Bélec
mesh_terms: D017954:Africa South of the Sahara; D000914:Antibodies, Viral / Q000097:blood*; D018258:Herpesvirus 2, Human / Q000276:immunology*; D006801:Humans; D007118:Immunoassay / Q000295:instrumentation* / Q000379:methods / Q000592:standards; D012680:Sensitivity and Specificity
chemical_list: D000914:Antibodies, Viral