title: Behavior of pharmaceuticals in waste water treatment plant in Japan.
abstract: The fate of pharmaceuticals in a wastewater treatment plant (WWTP) in Kumamoto, Japan with activated sludge treatment is reported. Selected pharmaceuticals were detected in influent. Results from the present study confirmed that Acetaminophen, Amoxicillin, Ampicillin and Famotidine were removed at a high rate (>90% efficiency). In contrast, removal efficiency of Ketoprofen, Losartan, Oseltamivir, Carbamazepine, and Diclofenac was relatively low (<50%). The selected pharmaceuticals were also detected in raw sludge. In digestive process, Indomethacin, Atenolol, Famotidine, Trimethoprim and Cyclofosamide were removed at a high (>70% efficiency). On the other hand, removal of Carbamazepine, Ketoprofen and Diclofenac was not efficient (<50%).
authors.affiliation: Graduate School of Environmental and Symbiotic Sciences, Prefectural University of Kumamoto, 3-1-100 Tsukide, Kumamoto 682-5802, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Matsuo
authors.forename: H
authors.initials: H
authors.lastname: Sakamoto
authors.forename: K
authors.initials: K
authors.lastname: Arizono
authors.forename: R
authors.initials: R
authors.lastname: Shinohara
mesh_terms: D000082:Acetaminophen / Q000302:isolation & purification; D000658:Amoxicillin / Q000302:isolation & purification; D000667:Ampicillin / Q000302:isolation & purification; D002220:Carbamazepine / Q000302:isolation & purification; D002853:Chromatography, Liquid; D004008:Diclofenac / Q000302:isolation & purification; D015738:Famotidine / Q000302:isolation & purification; D007564:Japan; D007660:Ketoprofen / Q000302:isolation & purification; D019808:Losartan / Q000302:isolation & purification; D013058:Mass Spectrometry; D053139:Oseltamivir / Q000302:isolation & purification; D012722:Sewage / Q000737:chemistry; D014295:Trimethoprim / Q000302:isolation & purification; D014865:Waste Disposal, Fluid / Q000379:methods*; D014874:Water Pollutants, Chemical / Q000302:isolation & purification*; D018508:Water Purification / Q000379:methods*
chemical_list: D012722:Sewage; D014874:Water Pollutants, Chemical; D004008:Diclofenac; D053139:Oseltamivir; D002220:Carbamazepine; D000082:Acetaminophen; D015738:Famotidine; D000667:Ampicillin; D000658:Amoxicillin; D007660:Ketoprofen; D014295:Trimethoprim; D019808:Losartan