title: In vitro biological and tribological properties of transparent magnesium aluminate (Spinel) and aluminum oxynitride (ALON®).
abstract: The purpose of this first generation investigation is to evaluate the in vitro cytotoxicity, cell-materials interactions and tribological performance of Spinel and ALON® transparent ceramics for potential wear resistant load bearing implant applications. Besides their non-toxicity, the high surface energy of these ceramics significantly enhanced in vitro cell-materials interactions compared to bioinert commercially pure Ti as control. These transparent ceramics with high hardness in the range of 1334 and 1543 HV showed in vitro wear rate of the order of 10⁻⁶ mm³ Nm⁻¹ against Al₂O₃ ball at a normal load of 20 N.
authors.affiliation: W. M. Keck Biomedical Materials Research Laboratory, School of Mechanical and Materials Engineering, Washington State University, Pullman, WA 99164-2920, USA.
authors.forename: Subhadip
authors.initials: S
authors.lastname: Bodhak
authors.forename: Vamsi Krishna
authors.initials: VK
authors.lastname: Balla
authors.forename: Susmita
authors.initials: S
authors.lastname: Bose
authors.forename: Amit
authors.initials: A
authors.lastname: Bandyopadhyay
authors.forename: Uday
authors.initials: U
authors.lastname: Kashalikar
authors.forename: Santosh K
authors.initials: SK
authors.lastname: Jha
authors.forename: Suri
authors.initials: S
authors.lastname: Sastri
mesh_terms: D000535:Aluminum / Q000737:chemistry*; D000537:Aluminum Oxide / Q000737:chemistry / Q000494:pharmacology*; D002478:Cells, Cultured; D002516:Ceramics / Q000737:chemistry / Q000494:pharmacology*; D006244:Hardness / Q000187:drug effects / Q000502:physiology; D006801:Humans; D008277:Magnesium Oxide / Q000737:chemistry / Q000494:pharmacology*; D008422:Materials Testing; D008855:Microscopy, Electron, Scanning; D010006:Osteoblasts / Q000187:drug effects / Q000502:physiology; D013499:Surface Properties
chemical_list: C562351:aluminum oxynitride; C111130:spinell; D008277:Magnesium Oxide; D000535:Aluminum; D000537:Aluminum Oxide