title: Complete reversal of nephrotic syndrome secondary to amyloidosis with use of infliximab in a patient with inflammatory bowel disease and ankylosing spondylitis.
abstract: A 30-year-old woman was diagnosed with ulcerative colitis in January 2006. One year later, she presented because of severe back pain and was diagnosed with ankylosing spondylitis (AS). In February 2008, the patient, while still under standard treatment for ulcerative colitis and AS, was admitted because of massive proteinuria and related symptoms. Nephrotic syndrome was observed and renal biopsy revealed amyloid deposits. After treatment with infliximab, nephrotic syndrome disappeared. We aim to present a case of secondary amyloidosis complicating ulcerative colitis and associated spondyloarthropathy.
authors.affiliation: Department of Internal Medicine, Section of Nephrology, Haydarpaşa Numune Training and Research Hospital, Istanbul, Turkey.
authors.forename: Mehmet Fatih
authors.initials: MF
authors.lastname: Akdoğan
authors.forename: Murat
authors.initials: M
authors.lastname: Gücün
authors.forename: Nazım
authors.initials: N
authors.lastname: Denizli
authors.forename: Murat
authors.initials: M
authors.lastname: Güney
authors.forename: Ibrahim
authors.initials: I
authors.lastname: Akdag
authors.forename: Tevhide Bilgen
authors.initials: TB
authors.lastname: Ozcan
authors.forename: Murat
authors.initials: M
authors.lastname: Duranay
mesh_terms: D000328:Adult; D000686:Amyloidosis / Q000150:complications*; D000911:Antibodies, Monoclonal / Q000627:therapeutic use*; D018501:Antirheumatic Agents / Q000627:therapeutic use*; D003093:Colitis, Ulcerative / Q000150:complications*; D005260:Female; D006801:Humans; D000069285:Infliximab; D009404:Nephrotic Syndrome / Q000188:drug therapy / Q000209:etiology*; D013167:Spondylitis, Ankylosing / Q000150:complications / Q000188:drug therapy*
chemical_list: D000911:Antibodies, Monoclonal; D018501:Antirheumatic Agents; D000069285:Infliximab