title: Effect of implant surface properties on peri-implant bone healing: a histological and histomorphometric study in dogs.
abstract: OBJECTIVE
  The present study aimed to evaluate and compare two types of implants, i.e. grit-blasted and acid-etched implants (SLActive(®)) with nano-meter-scale hydroxyapatite surface-modified implants (NanoTite™).
  
  
  METHODS
  For histological and histomorphometrical evaluation, 22 SLActive(®) and 22 Nanotite™ implants were inserted in eleven Beagle dogs. The animals were divided into three groups of healing (A: 2 weeks; B: 4 weeks and C: 8 weeks). Two, 4 and 8 weeks after implantation, the animals were sacrificed and bone-to-implant contact (BIC %), first implant-bone contact (1st BIC) as well as amount of bone (BV) were assessed.
  
  
  RESULTS
  For SLActive(®) and Nanotite™ implants, BIC% increased significantly over time. No statistically significant differences in BIC% were found between SLActive(®) and Nanotite™ at all the respective implantation times. Moreover, for the different healing periods, no significant differences for BV between SLActive(®) and Nanotite™ implants were found.
  
  
  CONCLUSIONS
  The present study showed that SLActive(®) and NanoTite™ implants induce a similar bone response after implantation for 2, 4 and 8 weeks in a non-submerged position in the mandible of dogs.
authors.affiliation: Department of Periodontology and Community Dentistry, College of Dentistry, King Saud University, Riyadh, Saudi Arabia.
authors.forename: Khalid
authors.initials: K
authors.lastname: Al-Hamdan
authors.forename: Samar H
authors.initials: SH
authors.lastname: Al-Moaber
authors.forename: Rüdiger
authors.initials: R
authors.lastname: Junker
authors.forename: John A
authors.initials: JA
authors.lastname: Jansen
mesh_terms: D000818:Animals; D015519:Bone Density; D020099:Coated Materials, Biocompatible; D045662:Dental Etching; D003758:Dental Implantation, Endosseous; D015921:Dental Implants; D017267:Dental Prosthesis Design; D004285:Dogs; D017886:Durapatite; D020007:Implants, Experimental; D008297:Male; D008334:Mandible / Q000601:surgery; D049329:Nanostructures; D016348:Osseointegration; D011897:Random Allocation; D013499:Surface Properties; D013997:Time Factors; D014025:Titanium
chemical_list: D020099:Coated Materials, Biocompatible; D015921:Dental Implants; D017886:Durapatite; D014025:Titanium