title: Long-range hydration effect of lipid membrane studied by terahertz time-domain spectroscopy.
abstract: The hydration state of biomolecules is believed to affect their self-assembly. The hydration state of phospholipid bilayers is studied precisely by terahertz spectroscopy, by which water perturbed by a lipid membrane is detected sensitively from the observation of the relaxation dynamics of water molecules in the subpicosecond time scale. Combined with x-ray observation of the lamellar structure of the lipid, a long-range hydration effect on up to 4-5 layers of water is confirmed. Most water molecules in the lamellae fall into the hydration water, and condensation of them is also indicated.
authors.affiliation: Institute for Integrated Cell-Material Sciences, Kyoto University, Kyoto 606-8501, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Hishida
authors.forename: K
authors.initials: K
authors.lastname: Tanaka
mesh_terms: D004134:Dimyristoylphosphatidylcholine / Q000031:analogs & derivatives* / Q000737:chemistry; D008051:Lipid Bilayers / Q000737:chemistry*; D008956:Models, Chemical; D010743:Phospholipids / Q000737:chemistry*; D053838:Scattering, Small Angle; D055068:Terahertz Spectroscopy / Q000379:methods*; D013997:Time Factors; D014867:Water / Q000737:chemistry*; D014961:X-Ray Diffraction
chemical_list: C108836:1,2-dimyristoyl-sn-glycero-3-ethylphosphocholine; D008051:Lipid Bilayers; D010743:Phospholipids; D014867:Water; D004134:Dimyristoylphosphatidylcholine