title: Microfluidic generation of multifunctional quantum dot barcode particles.
abstract: We develop a new strategy to prepare quantum dot (QD) barcode particles by polymerizing double-emulsion droplets prepared in capillary microfluidic devices. The resultant barcode particles are composed of stable QD-tagged core particles surrounded by hydrogel shells. These particles exhibit uniform spectral characteristics and excellent coding capability, as confirmed by photoluminescence analyses. By using double-emulsion droplets with two inner droplets of distinct phases as templates, we have also fabricated anisotropic magnetic barcode particles with two separate cores or with a Janus core. These particles enable optical encoding and magnetic separation, thus making them excellent functional barcode particles in biomedical applications.
authors.affiliation: State Key Laboratory of Bioelectronics, Southeast University, 210096 Nanjing, China.
authors.forename: Yuanjin
authors.initials: Y
authors.lastname: Zhao
authors.forename: Ho Cheung
authors.initials: HC
authors.lastname: Shum
authors.forename: Haosheng
authors.initials: H
authors.lastname: Chen
authors.forename: Laura L A
authors.initials: LL
authors.lastname: Adams
authors.forename: Zhongze
authors.initials: Z
authors.lastname: Gu
authors.forename: David A
authors.initials: DA
authors.lastname: Weitz
mesh_terms: D001330:Electronic Data Processing; D005898:Glass / Q000737:chemistry; D046210:Microfluidic Analytical Techniques; D058105:Polymerization; D045663:Quantum Dots; D012117:Resins, Synthetic / Q000737:chemistry
chemical_list: D012117:Resins, Synthetic