title: [Successful optimal debulking surgery following chemotherapy combined with irinotecan hydrochloride and cisplatin for advanced clear cell carcinoma of the ovary].
abstract: BACKGROUND
  Clear cell carcinoma of the ovary is known to be resistant to chemotherapy.
  
  
  METHODS
  A 59-year-old woman was diagnosed with advanced clear cell carcinoma of the ovary after an exploratory laparotomy. Large disseminated foci expanded from diaphragm to omentum to liver. Three courses of chemotherapy combined with irinotecan hydrochloride (CPT-11) and cisplatin (CDDP)(CPT-P) remarkably reduced the volume of the primary tumor and disseminated foci. These diseases could be extirpated completely by the subsequent interval debulking surgery.
  
  
  CONCLUSIONS
  CPT-P may become a promising regimen for clear cell carcinoma of the ovary.
authors.affiliation: Dept. of Obstetrics and Gynecology, Hirosaki University Graduate School of Medicine.
authors.forename: Hachidai
authors.initials: H
authors.lastname: Hirakawa
authors.forename: Masayuki
authors.initials: M
authors.lastname: Futagami
authors.forename: Yoshihito
authors.initials: Y
authors.lastname: Yokoyama
authors.forename: Kenichi
authors.initials: K
authors.lastname: Hakamada
authors.forename: Hideki
authors.initials: H
authors.lastname: Mizunuma
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002166:Camptothecin / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D002945:Cisplatin / Q000008:administration & dosage / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D000077146:Irinotecan; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D049268:Positron-Emission Tomography; D014057:Tomography, X-Ray Computed
chemical_list: D000077146:Irinotecan; D002945:Cisplatin; D002166:Camptothecin