title: Application of single nucleotide polymorphisms to non-model species: a technical review.
abstract: Single nucleotide polymorphisms (SNPs) have gained wide use in humans and model species and are becoming the marker of choice for applications in other species. Technology that was developed for work in model species may provide useful tools for SNP discovery and genotyping in non-model organisms. However, SNP discovery can be expensive, labour intensive, and introduce ascertainment bias. In addition, the most efficient approaches to SNP discovery will depend on the research questions that the markers are to resolve as well as the focal species. We discuss advantages and disadvantages of several past and recent technologies for SNP discovery and genotyping and summarize a variety of SNP discovery and genotyping studies in ecology and evolution.
authors.affiliation: Fisheries Division, School of Fisheries and Ocean Sciences, University of Alaska Fairbanks, 17101 Point Lena Loop Road, Juneau, AK 99801, USA National Research Institute of Fisheries Science, Fukuura, Kanazawa, Yokohama 236-8648 Japan.
authors.forename: M R
authors.initials: MR
authors.lastname: Garvin
authors.forename: K
authors.initials: K
authors.lastname: Saitoh
authors.forename: A J
authors.initials: AJ
authors.lastname: Gharrett