title: Cutaneous, mediastinal and hepatic hemangiomas in a girl followed during 12 years.
abstract: We present in this paper the case of a 12-year-old girl who had the clinical features of 2 different disorders: neurofibromatosis 1 (NF1) and 3 hemangiomas located in the skin, liver and mediastinum. The patient did not receive any specific treatment and showed a normal progressive evolution that lasted 1 / to 2 years and a very slow regression that lasted for a more prolonged time than expected (the 3 hemangiomas have not completely disappeared yet), although all 3 have been asymptomatic. MRI of the brain did not disclose a hemangioblastoma of the cerebellum or any other vascular lesion of the brain. Mental development of this girl was in the borderline range, as is commonly seen in Pascual-Castroviejo II syndrome (P-CIIS)/PHACE syndrome and in NF1, 2 syndromes which have not been reported to be associated in the same patient previously.
authors.affiliation: i.pcastroviejo@neurologia.e.telefonica.net
authors.forename: I
authors.initials: I
authors.lastname: Pascual-Castroviejo
authors.forename: M
authors.initials: M
authors.lastname: Parrón Pajares
authors.forename: S-I
authors.initials: SI
authors.lastname: Pascual-Pascual
authors.forename: P
authors.initials: P
authors.lastname: Jara
authors.forename: R
authors.initials: R
authors.lastname: Velázquez-Fragua
mesh_terms: D002648:Child; D005260:Female; D006391:Hemangioma / Q000150:complications*; D006801:Humans; D008113:Liver Neoplasms / Q000150:complications*; D008137:Longitudinal Studies; D008279:Magnetic Resonance Imaging; D008482:Mediastinum / Q000473:pathology*; D012878:Skin Neoplasms / Q000150:complications*