title: Screening of pharmaceuticals and hormones at the regional scale, in surface and groundwaters intended to human consumption.
abstract: As part of a regional screening to evaluate the risk, for the health of populations, to certain classes of emerging substances, several families of pharmaceuticals and hormones were looked for in waters intended to drinking. Thus, 52 substances were investigated in 71 surface waters and 70 groundwaters. Results indicate that no water was free of pollutants, regardless of its origin (surface or groundwater) and the season of collect. The pharmaceuticals most frequently detected and with the highest concentration levels were salicylic acid, carbamazepine and acetaminophen. Among hormones, testosterone, androstenedione and progesterone were detected in almost all the samples. Globally the groundwaters were less contaminated than surface waters in regards pharmaceuticals frequencies and levels. On the other side, androgens and progestagens were present with comparable frequencies and levels in both compartments. The risk linked to the presence of these substances on human health is discussed.
authors.affiliation: Institut des Sciences Analytiques - UMR5280, Département Service Central d'Analyse, Echangeur de Solaize, Chemin du Canal, F-69360 Solaize, France. e.vulliet@sca.cnrs.fr
authors.forename: Emmanuelle
authors.initials: E
authors.lastname: Vulliet
authors.forename: Cécile
authors.initials: C
authors.lastname: Cren-Olivé
mesh_terms: D000082:Acetaminophen / Q000032:analysis; D000735:Androstenedione / Q000032:analysis; D002220:Carbamazepine / Q000032:analysis; D004781:Environmental Exposure / Q000032:analysis* / Q000706:statistics & numerical data; D005618:Fresh Water / Q000737:chemistry*; D060587:Groundwater / Q000737:chemistry*; D006728:Hormones / Q000032:analysis*; D006801:Humans; D004364:Pharmaceutical Preparations / Q000032:analysis*; D011374:Progesterone / Q000032:analysis; D018570:Risk Assessment; D020156:Salicylic Acid / Q000032:analysis; D013739:Testosterone / Q000032:analysis; D014874:Water Pollutants, Chemical / Q000032:analysis*; D014881:Water Supply / Q000032:analysis*
chemical_list: D006728:Hormones; D004364:Pharmaceutical Preparations; D014874:Water Pollutants, Chemical; D002220:Carbamazepine; D000082:Acetaminophen; D013739:Testosterone; D000735:Androstenedione; D011374:Progesterone; D020156:Salicylic Acid