title: Diffusion spectral imaging modules correlate with EEG LORETA neuroimaging modules.
abstract: OBJECTIVE
  The purpose of this study was to test the hypothesis that the highest temporal correlations between 3-dimensional EEG current source density corresponds to anatomical Modules of high synaptic connectivity.
  
  
  METHODS
  Eyes closed and eyes open EEG was recorded from 19 scalp locations with a linked ears reference from 71 subjects age 13-42 years. LORETA was computed from 1 to 30 Hz in 2,394 cortical gray matter voxels that were grouped into six anatomical Modules corresponding to the ROIs in the Hagmann et al.'s [2008] diffusion spectral imaging (DSI) study. All possible cross-correlations between voxels within a DSI Module were compared with the correlations between Modules.
  
  
  RESULTS
  The Hagmann et al. [ 2008] Module correlation structure was replicated in the correlation structure of EEG three-dimensional current source density.
  
  
  CONCLUSIONS
  EEG Temporal correlation between brain regions is related to synaptic density as measured by diffusion spectral imaging.
authors.affiliation: NeuroImaging Laboratory, Applied Neuroscience Research Institute, St. Petersburg, Florida 33722, USA. rwthatcher@yahoo.com
authors.forename: Robert W
authors.initials: RW
authors.lastname: Thatcher
authors.forename: Duane M
authors.initials: DM
authors.lastname: North
authors.forename: Carl J
authors.initials: CJ
authors.lastname: Biver
mesh_terms: D000293:Adolescent; D000328:Adult; D001931:Brain Mapping / Q000379:methods*; D004569:Electroencephalography / Q000379:methods*; D004574:Electromagnetic Fields; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D008297:Male; D009415:Nerve Net / Q000502:physiology*; D059906:Neuroimaging / Q000379:methods*; D055815:Young Adult