title: Oral hypoglycemic agents in pregnancy.
abstract: Multiple studies have been published illustrating the use of oral hypoglycemic agents in pregnancy. Glyburide and metformin have been shown to be as effective as insulin for the treatment of gestational diabetes. Both are safe with breastfeeding. Although both glyburide and metformin appear safe for the treatment of type 2 diabetes mellitus, more studies are needed to support this practice.
authors.affiliation: Division of Maternal Fetal Medicine, Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Texas Health Science Center at Houston, Houston, TX 77030, USA. jerrie.s.refuerzo@uth.tmc.edu
authors.forename: Jerrie S
authors.initials: JS
authors.lastname: Refuerzo
mesh_terms: D000284:Administration, Oral; D001942:Breast Feeding; D016640:Diabetes, Gestational / Q000188:drug therapy*; D005260:Female; D005905:Glyburide / Q000008:administration & dosage / Q000009:adverse effects; D006801:Humans; D007004:Hypoglycemic Agents / Q000008:administration & dosage* / Q000009:adverse effects; D007328:Insulin / Q000008:administration & dosage; D008687:Metformin / Q000008:administration & dosage / Q000009:adverse effects; D011247:Pregnancy; D016896:Treatment Outcome
chemical_list: D007004:Hypoglycemic Agents; D007328:Insulin; D008687:Metformin; D005905:Glyburide