title: Phenolic compounds from Byrsonima crassifolia L. bark: phytochemical investigation and quantitative analysis by LC-ESI MS/MS.
abstract: Phytochemical investigation of the methanolic extract of Byrsonima crassifolia's bark led to the isolation of 8 known phenolic compounds 5-O-galloylquinic acid, 3-O-galloylquinic acid, 3,4-di-O-galloylquinic acid, 3,5-di-O-galloylquinic acid, 3,4,5-tri-O-galloylquinic acid, (+)-epicatechin-3-gallate along with (+)-catechin and (+)-epicatechin. Due to their biological value, in the present study, a high-performance liquid chromatography-tandem mass spectrometry (LC-MS/MS) method, working in multiple reaction monitoring (MRM) mode, has been developed to quantify these compounds. B. crassifolia bark resulted in a rich source of phenolic compounds and particularly of galloyl derivates. The proposed analytical method is promising to be applied to other galloyl derivatives to quantify these bioactive compounds in raw material and final products.
authors.affiliation: Dipartimento di Scienze Farmaceutiche, Università degli Studi di Salerno, Via Ponte don Melillo, 84084 Fisciano (SA), Italy.
authors.forename: Mariateresa
authors.initials: M
authors.lastname: Maldini
authors.forename: Paola
authors.initials: P
authors.lastname: Montoro
authors.forename: Cosimo
authors.initials: C
authors.lastname: Pizza
mesh_terms: D001531:Belize; D002851:Chromatography, High Pressure Liquid; D029581:Malpighiaceae / Q000737:chemistry* / Q000254:growth & development; D015394:Molecular Structure; D010636:Phenols / Q000737:chemistry / Q000302:isolation & purification*; D024301:Plant Bark / Q000737:chemistry / Q000254:growth & development; D010936:Plant Extracts / Q000302:isolation & purification*; D021241:Spectrometry, Mass, Electrospray Ionization; D053719:Tandem Mass Spectrometry
chemical_list: D010636:Phenols; D010936:Plant Extracts