title: Expression of sex-hormone receptors and clinicopathological findings in hepatocellular-carcinoma.
abstract: We studied the expresssion of estrogen (ER), progesterone (PgR), and androgen receptors (AR) in hepatocellular carcinoma (HCC) and found expression in (7/36), 3.2% (1/31), 16.7% (4/24) of cases, respectively. The expression of ER did not correlate with histological grade, tumor size, or stage of disease. On the other hand, all the patients with AR-positive tumors had stage IV disease, and only 25% of the patients with AR-negative tumors had stage IV disease. The survival was not influenced by the expression pattern of ER, however, the survival of the patients with AR-positive tumors tended to be worse than that of patients with AR-negative tumors. We suggest that the AR expression correlates better with poor outcome in HCC than the ER expression.
authors.forename: H
authors.initials: H
authors.lastname: Ishizu
authors.forename: Y
authors.initials: Y
authors.lastname: Une
authors.forename: H
authors.initials: H
authors.lastname: Gondo
authors.forename: H
authors.initials: H
authors.lastname: Kameda
authors.forename: J
authors.initials: J
authors.lastname: Uchino