title: Biology of germ cell tumors.
abstract: Testicular cancer has been a model for a curable malignancy. The existence of an array of potential new therapies is the result of a prodigious effort in the researching and defining of the molecular components of the cancer phenotype and the subsequent rational design of agents to target candidate pathways. A better understanding of the molecular biology of cancer may also aid in guiding the most appropriate use of existing therapies, such as conventional chemotherapy.
authors.affiliation: The Cancer Centre, University Hospital Birmingham NHS Foundation Trust, Edgbaston, Birmingham B15 2TH, UK.
authors.forename: Yuk Ting
authors.initials: YT
authors.lastname: Ma
authors.forename: Michael H
authors.initials: MH
authors.lastname: Cullen
authors.forename: Syed A
authors.initials: SA
authors.lastname: Hussain
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use; D002869:Chromosome Aberrations; D019008:Drug Resistance, Neoplasm / Q000235:genetics*; D044127:Epigenesis, Genetic; D020022:Genetic Predisposition to Disease / Q000235:genetics; D006801:Humans; D008297:Male; D008967:Molecular Biology; D009373:Neoplasms, Germ Cell and Embryonal / Q000188:drug therapy / Q000235:genetics*; D013736:Testicular Neoplasms / Q000188:drug therapy / Q000235:genetics*
chemical_list: D000970:Antineoplastic Agents