title: Varicella-zoster virus (chickenpox) infection in pregnancy.
abstract: Congenital varicella syndrome, maternal varicella-zoster virus pneumonia and neonatal varicella infection are associated with serious fetomaternal morbidity and, not infrequently, mortality. Vaccination against varicella-zoster virus can prevent the disease, and outbreak control limits the exposure of pregnant women to the infectious agent. Maternal varicella-zoster immunoglobulin administration before rash development, with or without antiviral medication, can modify the progression of the disease.
authors.affiliation: Perinatology Research Branch, NICHD/NIH/DHHS, Bethesda, MD, USA. rlamont@med.wayne.edu
authors.forename: Ronald F
authors.initials: RF
authors.lastname: Lamont
authors.forename: Jack D
authors.initials: JD
authors.lastname: Sobel
authors.forename: D
authors.initials: D
authors.lastname: Carrington
authors.forename: Shali
authors.initials: S
authors.lastname: Mazaki-Tovi
authors.forename: Juan Pedro
authors.initials: JP
authors.lastname: Kusanovic
authors.forename: Edi
authors.initials: E
authors.lastname: Vaisbuch
authors.forename: Roberto
authors.initials: R
authors.lastname: Romero
mesh_terms: D002644:Chickenpox / Q000151:congenital / Q000517:prevention & control; D005260:Female; D005315:Fetal Diseases / Q000517:prevention & control; D005865:Gestational Age; D006801:Humans; D007106:Immune Sera / Q000008:administration & dosage; D007231:Infant, Newborn; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000517:prevention & control; D014611:Vaccination
chemical_list: D007106:Immune Sera; C030799:varicella-zoster immune globulin