title: Anticancer gold(I)-phosphine complexes as potent autophagy-inducing agents.
abstract: A panel of anticancer gold(I)-phosphine complexes exhibit significant autophagy-inducing properties in cancer cells.
authors.affiliation: Department of Chemistry, State Key Laboratory on Synthetic Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong SAR, China.
authors.forename: Songhai
authors.initials: S
authors.lastname: Tian
authors.forename: Fung-Ming
authors.initials: FM
authors.lastname: Siu
authors.forename: Steven C F
authors.initials: SC
authors.lastname: Kui
authors.forename: Chun-Nam
authors.initials: CN
authors.lastname: Lok
authors.forename: Chi-Ming
authors.initials: CM
authors.lastname: Che
mesh_terms: D000970:Antineoplastic Agents / Q000737:chemistry* / Q000633:toxicity; D001343:Autophagy / Q000187:drug effects*; D045744:Cell Line, Tumor; D056831:Coordination Complexes / Q000737:chemistry* / Q000633:toxicity; D004354:Drug Screening Assays, Antitumor; D006046:Gold / Q000737:chemistry*; D006801:Humans; D008869:Microtubule-Associated Proteins / Q000378:metabolism; D010720:Phosphines / Q000737:chemistry*; D013329:Structure-Activity Relationship
chemical_list: D000970:Antineoplastic Agents; D056831:Coordination Complexes; C477012:MAP1LC3A protein, human; D008869:Microtubule-Associated Proteins; D010720:Phosphines; D006046:Gold; C044646:phosphine