title: [Detect myelin structure in acoustic tumor].
abstract: OBJECTIVE
  By detecting the myelin structure in acoustic tumor tissues, the cell origin and state of acoustic tumor tissues were investigated.
  
  
  METHODS
  Immunofluorescence labeling, immunoblot analysis and electron microscopic study were performed to identify myelin structure and myelin protein in acoustic tumor tissues.
  
  
  RESULTS
  In this work, we found some early stage of myelin forming in acoustic tumor tissues, but there were no axon nor compact myelin formed and the myelin basic protein whose expression indicates the beginning of myelination was negative detected. We also found that the cell of acoustic tumor express p75,a marker for immature Schwann cells and mature non-myelin-forming Schwann cells.
  
  
  CONCLUSIONS
  The date shown in this experiment indicates that the cell of acoustic tumor is in a remyelinating state.
authors.affiliation: Department of Otolaryngology, the First Affiliated Hospital of China Medical University, Shenyang, 110001, China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Wang
authors.forename: Haiyang
authors.initials: H
authors.lastname: Jiang
authors.forename: He
authors.initials: H
authors.lastname: Yu
authors.forename: Chao
authors.initials: C
authors.lastname: Guan
authors.forename: Xuejun
authors.initials: X
authors.lastname: Jiang
mesh_terms: D006801:Humans; D008854:Microscopy, Electron; D009186:Myelin Sheath / Q000473:pathology* / Q000648:ultrastructure; D009464:Neuroma, Acoustic / Q000473:pathology*; D012583:Schwann Cells / Q000473:pathology*