title: [Management of acute myocardial infarction: What remains of intravenous thrombolysis?].
abstract: ST elevation myocardial infarction (STEMI) is related to acute occlusion of a coronary artery by a fibrin reach thrombus. Early reperfusion may reduce infarct size and improve prognosis. Percutaneous coronary intervention (PCI) is more effective than intravenous fibrinolysis (IVF). Fibrinolysis remains useful in patients when PCI is not feasible. IVF has largely contributed to the knowledge of the physiopathology of STEMI and its management.
authors.affiliation: CHU Timone, service de cardiologie A, 13, 13385 Marseille, France. Jean-louis.BONNET@ap-hm.fr
authors.forename: Jean-Louis
authors.initials: JL
authors.lastname: Bonnet
authors.forename: Guillaume
authors.initials: G
authors.lastname: Bonnet
mesh_terms: D015906:Angioplasty, Balloon, Coronary; D002986:Clinical Trials as Topic; D003131:Combined Modality Therapy; D019468:Disease Management; D042241:Early Diagnosis; D004632:Emergency Medical Services; D005343:Fibrinolytic Agents / Q000008:administration & dosage* / Q000009:adverse effects / Q000627:therapeutic use; D006801:Humans; D007262:Infusions, Intravenous; D007275:Injections, Intravenous; D015337:Multicenter Studies as Topic; D009203:Myocardial Infarction / Q000175:diagnosis / Q000188:drug therapy* / Q000401:mortality / Q000628:therapy; D015425:Myocardial Reperfusion / Q000379:methods* / Q000639:trends; D015912:Thrombolytic Therapy / Q000379:methods* / Q000639:trends; D013997:Time Factors
chemical_list: D005343:Fibrinolytic Agents