title: [CRP and micro-albumin: new markers of cardiovascular risk in type 2 diabetes].
abstract: BACKGROUND
  Type 2 diabetes is a chronic disease associated to the presence of multiple risk factors. Among recently studied factors we cite PCR and micro-albumin.
  
  
  OBJECTIVE
  In the present study we intend to determine the correlation between urine albumin excretion rate, CRP levels and type of vascular complications in type 2 diabetes.
  
  
  METHODS
  We recruited 48 type 2 diabetic subjects subdivided into three groups according to the type of vascular complications (GI: type 2 diabetics without complications, GII: type 2 diabetics with microvascular complications and GIII: type 2 diabetics with macrovascular complications).
  
  
  RESULTS
  We found a significant elevated levels of CRP and micro-albumin (P<0.05) when we compared diabetics with vascular complications to those without any complications. Diabetics with macrovascular complications have the highest levels of CRP and micro-albumin. Significant positive correlation was found between CRP and micro-albumin levels in a total group of diabetics (r=0.32; P<0.05).
  
  
  CONCLUSIONS
  The determination of CRP and microalbumin levels represents an interest in the screening of cardiovascular disease in type 2 diabetics.
authors.affiliation: Laboratoire de biochimie, hôpital militaire principal d'instruction, Montfleury, Tunis, Tunisie. doc mo@ymail.com
authors.forename: M
authors.initials: M
authors.lastname: El Oudi
authors.forename: Z
authors.initials: Z
authors.lastname: Aouni
authors.forename: H
authors.initials: H
authors.lastname: Ouertani
authors.forename: C
authors.initials: C
authors.lastname: Mazigh
authors.forename: B
authors.initials: B
authors.lastname: Nsiri
authors.forename: B
authors.initials: B
authors.lastname: Zidi
authors.forename: S
authors.initials: S
authors.lastname: Machghoul
mesh_terms: D000419:Albuminuria / Q000209:etiology*; D015415:Biomarkers / Q000032:analysis; D002097:C-Reactive Protein / Q000032:analysis*; D002318:Cardiovascular Diseases / Q000209:etiology*; D003924:Diabetes Mellitus, Type 2 / Q000150:complications* / Q000378:metabolism*; D003925:Diabetic Angiopathies / Q000209:etiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012307:Risk Factors
chemical_list: D015415:Biomarkers; D002097:C-Reactive Protein