title: Fibrocartilaginous mesenchymoma, a unique osseous lesion: case report with review of the literature.
abstract: Fibrocartilaginous mesenchymoma is a rare osseous tumor that primarily arises in the long bones of children and adolescents. This lesion can grow quickly and reach a considerable size, despite its benign nature. It has proved challenging to diagnose and can be mistaken for a spectrum of benign and malignant bone tumors. The histological presentation of unique epiphyseal plate-like cartilage with destruction of the surrounding cortical bone and exhibition of dense fibrous stroma are important indicators for the diagnosis of fibrocartilaginous mesenchymoma. An 11-year-old boy presented with a left proximal humerus mass thought to be an aneurysmal bone cyst. The patient was lost to follow-up and came back 3 years later with massive growth of the lesion. Owing to the aggressive nature of the tumor, a left forequarter amputation was performed. Histological examination demonstrated numerous islands of cartilage with an exuberant spindle cell component characteristic of FCM. No distant metastases or local recurrences were identified at 2 years post-amputation. Because of the rapid growth of this lesion, it should be considered in the differential diagnosis of bone lesions in children and young adults.
authors.affiliation: Pathology, Children's Healthcare of Atlanta, Atlanta, GA 30322, USA.
authors.forename: Jenny
authors.initials: J
authors.lastname: Lin
authors.forename: Sarah Catherine
authors.initials: SC
authors.lastname: Shulman
authors.forename: Charlotte Katherine
authors.initials: CK
authors.lastname: Steelman
authors.forename: Shervin V
authors.initials: SV
authors.lastname: Oskouei
authors.forename: John D
authors.initials: JD
authors.lastname: Reith
authors.forename: Stephen F
authors.initials: SF
authors.lastname: Simoneaux
authors.forename: Thomas A
authors.initials: TA
authors.lastname: Olson
authors.forename: Bahig M
authors.initials: BM
authors.lastname: Shehata
mesh_terms: D000293:Adolescent; D001859:Bone Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D006801:Humans; D006811:Humerus / Q000000981:diagnostic imaging / Q000473:pathology; D008297:Male; D008637:Mesenchymoma / Q000000981:diagnostic imaging / Q000473:pathology*; D011859:Radiography