title: Obsessive - compulsive symptoms during clozapine treatment.
abstract: Development of obsessive-compulsive symptoms during clozapine treatment in schizophrenics has been noted in few reports from west. In our cases, three schizophrenic patients resistant to typical antipsychotics developed obsessive-compulsive symptoms during clozapine treatment. Since clozapine is a potent 5-HT(2) receptor blocker, role of serotonergic systems in the development of obsessive-compulsive symptoms may be considered. It may be prudent to be vigilant for the emergence of obsessive-compulsive symptoms in all patients treated with clozapine.
authors.affiliation: A.K. AGARWAL, M.D., D.P.M., Professor & Head, Department of Psychiatry, K.G. Medical College, Lucknow-226003.
authors.forename: A K
authors.initials: AK
authors.lastname: Agarwal
authors.forename: A
authors.initials: A
authors.lastname: Khalid