title: [External respiratory function in patients with Crohn's disease].
abstract: This article presents the results of a study of respiratory function (SRF) in 56 patients with Crohn's disease (CD) who were hospitalized in the Department of intestine pathology in Central research institute of gastroenterology. SRF was determined by spirography and registration of the curve flow--volume forced exhale ("Eton-1, RF). Violations of pulmonary function in CD occurred in 44.6% of patients, which exceeded the rate of violations in the control group (60 healthy individuals) is about 5 times (p < 0.001). Identified breaches were presented in most cases with obstructive pathology of bronchial tubes, much less restrictive observed (8.0%) and mixed (16.0%), disorders of ventilation. The highest frequency of pulmonary function was observed during prolonged (more than 10 years) history of illness (81.2%) and in patients with ileocolitis (64.7%).
authors.forename: Z F
authors.initials: ZF
authors.lastname: Mikhaĭlova
authors.forename: A I
authors.initials: AI
authors.lastname: Parfenov
authors.forename: I N
authors.initials: IN
authors.lastname: Ruchkina
authors.forename: V A
authors.initials: VA
authors.lastname: Rogozina
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D003424:Crohn Disease / Q000150:complications / Q000453:epidemiology / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012129:Respiratory Function Tests; D012131:Respiratory Insufficiency / Q000150:complications / Q000453:epidemiology / Q000503:physiopathology*; D013997:Time Factors; D055815:Young Adult