title: Finer snapshot of circulating Mycobacterium tuberculosis genotypes in Guadeloupe, Martinique, and French Guiana.
abstract: This study shows the benefit of spoligotyping coupled to mycobacterial interspersed repetitive-unit (MIRU) typing to pinpoint circulating Mycobacterium tuberculosis genotypes in Guadeloupe, Martinique, and French Guiana. We hereby propose reduced 4-locus and 6-locus subsets for LAM and Haarlem lineage strains that predominate in South America and the Caribbean, retaining 99.35% and 99.64% of the total discriminatory power of the 12-locus scheme, respectively.
authors.affiliation: WHO Supranational TB Reference Laboratory, Unité de la Tuberculose et des Mycobactéries, Institut Pasteur de Guadeloupe, Abymes, Guadeloupe, France.
authors.forename: Julie
authors.initials: J
authors.lastname: Millet
authors.forename: William
authors.initials: W
authors.lastname: Laurent
authors.forename: Thierry
authors.initials: T
authors.lastname: Zozio
authors.forename: Nalin
authors.initials: N
authors.lastname: Rastogi
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004269:DNA, Bacterial / Q000235:genetics; D005616:French Guiana / Q000453:epidemiology; D005838:Genotype; D019430:Guadeloupe / Q000453:epidemiology; D006801:Humans; D008297:Male; D008395:Martinique / Q000453:epidemiology; D008875:Middle Aged; D017720:Molecular Epidemiology / Q000379:methods; D058889:Molecular Typing; D009169:Mycobacterium tuberculosis / Q000145:classification* / Q000235:genetics* / Q000302:isolation & purification; D014376:Tuberculosis / Q000453:epidemiology* / Q000382:microbiology*; D055815:Young Adult
chemical_list: D004269:DNA, Bacterial