title: Autoimmune progesterone dermatitis: a diagnosis easily missed.
abstract: Autoimmune progesterone dermatitis (AIPD) is a rare, poorly characterized dermatosis, with about 60 previously reported cases. It typically undergoes cyclical flares relating to the menstrual cycle, especially the luteal phase, when levels of progesterone are at their highest. We report the case of a 34-year-old woman with an 8-year history of a profoundly pruritic eruption, associated with her menstrual cycle, in whom the diagnosis had proved elusive. Buserelin nasal spray resulted in complete clearance. AIPD is a diagnosis to consider in intractable eruptions in women, particularly if there is cyclical variation.
authors.affiliation: Department of Dermatology, Great Western Hospital NHS Foundation Trust, Swindon, Wiltshire, UK.
authors.forename: L M
authors.initials: LM
authors.lastname: Toms-Whittle
authors.forename: L H
authors.initials: LH
authors.lastname: John
authors.forename: D J
authors.initials: DJ
authors.lastname: Griffiths
authors.forename: D A
authors.initials: DA
authors.lastname: Buckley
mesh_terms: D000328:Adult; D001327:Autoimmune Diseases / Q000188:drug therapy / Q000276:immunology* / Q000473:pathology; D002064:Buserelin / Q000627:therapeutic use; D003872:Dermatitis; D005260:Female; D007987:Gonadotropin-Releasing Hormone / Q000627:therapeutic use; D006801:Humans; D008597:Menstrual Cycle / Q000276:immunology*; D011374:Progesterone / Q000009:adverse effects / Q000276:immunology*; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D007987:Gonadotropin-Releasing Hormone; D011374:Progesterone; D002064:Buserelin