title: A novel and unusually long-lived chemiluminophore based on the 7-hydroxycoumarin scaffold.
abstract: Synthesis and chemiluminescent properties of a new 1,2-dioxetane chemiluminophore bearing a 7-hydroxycoumarin moiety are presented. The 1,2-dioxetane decomposition ended up with strong and long-lived emission of light. This new structure opens way to the development of a new generation of bright chemiluminescent bio-probes.
authors.affiliation: Equipe de Chimie Bio-Organique, COBRA-CNRS UMR 6014 & FR 3038, rue Lucien Tesnière, 76131 Mont-Saint-Aignan, France.
authors.forename: Jan
authors.initials: J
authors.lastname: Kočí
authors.forename: Virgile
authors.initials: V
authors.lastname: Grandclaude
authors.forename: Marc
authors.initials: M
authors.lastname: Massonneau
authors.forename: Jean-Alexandre
authors.initials: JA
authors.lastname: Richard
authors.forename: Anthony
authors.initials: A
authors.lastname: Romieu
authors.forename: Pierre-Yves
authors.initials: PY
authors.lastname: Renard
mesh_terms: D004735:Energy Transfer; D006571:Heterocyclic Compounds / Q000138:chemical synthesis / Q000737:chemistry; D006573:Heterocyclic Compounds, 1-Ring; D049408:Luminescent Agents / Q000138:chemical synthesis / Q000737:chemistry*; D008163:Luminescent Measurements; D014468:Umbelliferones / Q000737:chemistry*
chemical_list: D006571:Heterocyclic Compounds; D006573:Heterocyclic Compounds, 1-Ring; D049408:Luminescent Agents; D014468:Umbelliferones; C079142:1,2-dioxetane; C031477:7-hydroxycoumarin