title: [Clinical and morphological criteria for microscopic ischemic colitis in patients with chronic coronary heart disease of the digestive system].
abstract: We studied the clinical symptoms and functional-morphological changes of the colon in 42 patients with cardiovascular disease, impaired blood flow in the unpaired visceral branches of the abdominal aorta, clinical and instrumental signs of ischemic colon lesions (ICL). Clinical symptoms characteristic of intestinal pathology were observed in all patients, but traditionally described laboratory-instrumental signs of ischemic colitis are installed in only two of them. At the same time, the histological study of the mucosa of the sigmoid colon in 21 of 23 patients revealed necrosis of surface epithelium, reducing the number of goblet cells, focal lymphoid-cell infiltrates and microcirculatory disturbances with the development of stasis, thrombosis and microcirculatory plazmorrags of the colon mucosa. Thus, we have established a new form of ICL--microscopic ischemic colitis. It is the morphological evidence of abdominal pain syndrome, observed in most patients with chronic abdominal ischemia.
authors.forename: N G
authors.initials: NG
authors.lastname: Samsonova
authors.forename: L A
authors.initials: LA
authors.lastname: Zvenigorodskaia
authors.forename: A I
authors.initials: AI
authors.lastname: Parfenov
authors.forename: S G
authors.initials: SG
authors.lastname: Khomeriki
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002908:Chronic Disease; D017091:Colitis, Ischemic / Q000150:complications / Q000473:pathology* / Q000503:physiopathology; D003106:Colon / Q000098:blood supply / Q000473:pathology* / Q000503:physiopathology; D003327:Coronary Disease / Q000150:complications / Q000473:pathology* / Q000503:physiopathology; D005260:Female; D006801:Humans; D007413:Intestinal Mucosa / Q000098:blood supply / Q000473:pathology* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged