title: Resting energy expenditure in patients undergoing pylorus preserving pancreatoduodenectomies for bile duct cancer or pancreatic tumors.
abstract: We measured the energy expenditure weekly in patients undergoing a pylorus preserving pancreatoduodenectomy for bile duct cancer or pancreatic tumors. Twelve patients (5 women and 7 men; mean age 70.1 years) were enrolled in this study, and their resting energy expenditure levels were determined by indirect calorimetry. In these patients, a significant correlation was observed between the measured resting energy expenditures and the predicted resting energy expenditures calculated by the Harris-Benedict equation. The resting energy expenditures measured before surgery were almost the same as the predicted resting energy expenditures (measured resting energy expenditure: 22.4 ± 3.9 kcal/kg/day vs predicted resting energy expenditure: 21.7 ± 2.0 kcal/kg/day). The measured resting energy expenditure/predicted resting energy expenditure ratio, which reflects the stress factor, was 1.02 ± 0.10. After the pylorus preserving pancreatoduodenectomy, a significant increase in energy expenditure was observed, and the measured resting energy expenditure was 25.7 ± 3.5 kcal/kg/day on postoperative day 7 and 25.4 ± 4.9 kcal/kg/day on postoperative day 14. The measured resting energy expenditure/predicted resting energy expenditure ratio was 1.16 ± 0.14 on postoperative day 7, and 1.16 ± 0.18 on postoperative day 14 respectively. In conclusion, patients undergoing a pylorus preserving pancreatoduodenectomy showed a hyper-metabolic status as evaluated by their measured resting energy expenditure/predicted resting energy expenditure ratio. From our observations, we recommend that nutritional management based on 30 kcal/body weight/day (calculated by the measured resting energy expenditure×activity factor 1.2-1.3) may be optimal for patients undergoing a pylorus preserving pancreatoduodenectomy.
authors.affiliation: Division of Clinical Nutrition, Shiga University of Medical Science, Seta-Tsukinowa, Otsu, Shiga 520-2192, Japan.
authors.forename: Masaya
authors.initials: M
authors.lastname: Sasaki
authors.forename: Haruka
authors.initials: H
authors.lastname: Okamoto
authors.forename: Tomoko
authors.initials: T
authors.lastname: Johtatsu
authors.forename: Mika
authors.initials: M
authors.lastname: Kurihara
authors.forename: Hiromi
authors.initials: H
authors.lastname: Iwakawa
authors.forename: Toshihiro
authors.initials: T
authors.lastname: Tanaka
authors.forename: Hisanori
authors.initials: H
authors.lastname: Shiomi
authors.forename: Shigeyuki
authors.initials: S
authors.lastname: Naka
authors.forename: Yoshimasa
authors.initials: Y
authors.lastname: Kurumi
authors.forename: Tohru
authors.initials: T
authors.lastname: Tani