title: [Antiplatelet and anticoagulant therapy in elderly patients].
abstract: Managing antithrombotic therapy in elderly patients presents significant practical problems due to the lack of specifically designed studies, practical recommendations from guidelines, and the difficulty of identifying the right balance between benefits in reducing ischemic events and increased risk of bleeding complications. In addition, in elderly subjects, the pharmacokinetics and pharmacodynamics of antiplatelet and anticoagulant agents often have a quite peculiar connotation. This article reviews the evidence supporting the use of antithrombotic drugs in elderly patients with ischemic heart disease.
authors.affiliation: Dipartimento di Cardiologia, Ospedale Ferrarotto, Università degli Studi, Catania. dcapodanno@gmail.com
authors.forename: Davide
authors.initials: D
authors.lastname: Capodanno
authors.forename: Dominick J
authors.initials: DJ
authors.lastname: Angiolillo
authors.forename: Corrado
authors.initials: C
authors.lastname: Tamburino
mesh_terms: D000368:Aged; D000375:Aging / Q000502:physiology; D000925:Anticoagulants / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D017202:Myocardial Ischemia / Q000188:drug therapy*; D010975:Platelet Aggregation Inhibitors / Q000009:adverse effects / Q000627:therapeutic use*; D017410:Practice Guidelines as Topic
chemical_list: D000925:Anticoagulants; D010975:Platelet Aggregation Inhibitors