title: [Chagas disease Control Program in the State of São Paulo, Brazil: serological and entomological aspects of primary school-children surveys].
abstract: Two serological surveys were carried out to evaluate the effectiveness of measures put into effect in the State of São Paulo (Brazil) to control Chagas disease vectors. The first one, during the period from 1968 to 1970; the complement fixation reaction was performed on serum samples from school-children resident in all municipalities of the State of São Paulo, with the exception of the Greater São Paulo. The second one, annually, from 1973 to 1983, involving school-children resident in municipalities with high trypanosomiasis prevalence values; the indirect immuno-fluorescence test was performed on filter paper total blood eluates. Data on the occurrence of triatomines and their infection with Trypanosoma cruzi in each municipality formed the basis of insight into the epidemiological situation associated with the school-children's dates of birth. Most positive serological results, as well as the highest proportion of autochthonous cases associated with Triatoma infestans were observed in the region of Sorocaba until the early 1970s, while the proportions of both autochthonous and imported cases were kept in equilibrium elsewhere. It has been inferred that as recently as 1974, vectorial transmission of Chagas disease could still be observed in the State of São Paulo. We emphasize that, even rather lacking in coverage, no seropositive cases have been observed in people inhabiting the regions included in the Control Program for the State of São Paulo and now aged less than 15 years.
authors.affiliation: Laboratório de Imunoepidemiologia, Superintendência de Controle de Endemias, Secretaria de Estado da Saúde, São Paulo, SP, Brazil. esther@sucen.sp.gov.br
authors.forename: Maria Esther de
authors.initials: ME
authors.lastname: Carvalho
authors.forename: Rubens Antonio da
authors.initials: RA
authors.lastname: Silva
authors.forename: Dalva Marli Valério
authors.initials: DM
authors.lastname: Wanderley
authors.forename: José Maria Soares
authors.initials: JM
authors.lastname: Barata
mesh_terms: D000293:Adolescent; D000818:Animals; D001938:Brazil / Q000453:epidemiology; D014355:Chagas Disease / Q000453:epidemiology / Q000517:prevention & control*; D002648:Child; D005260:Female; D006801:Humans; D007303:Insect Vectors / Q000145:classification / Q000469:parasitology*; D008297:Male; D011159:Population Surveillance; D015995:Prevalence; D012424:Rural Population; D016036:Seroepidemiologic Studies; D013334:Students / Q000706:statistics & numerical data; D014225:Triatominae / Q000145:classification / Q000469:parasitology*