title: A concise construction of the chlorahololide heptacyclic core.
abstract: A concise and efficient strategy for the construction of the heptacyclic core of the chloranthaceae family has been developed. The key strategy comprises an S(N)2-type intramolecular nucleophilic substitution and a biomimetic endo-Diels-Alder cycloaddition.
authors.affiliation: Department of Chemistry and State Key Laboratory on Synthetic Chemistry, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China.
authors.forename: Yin-Suo
authors.initials: YS
authors.lastname: Lu
authors.forename: Xiao-Shui
authors.initials: XS
authors.lastname: Peng
mesh_terms: D003500:Cyclization; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D012717:Sesquiterpenes / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D012717:Sesquiterpenes; C519126:chlorahololide A