title: Generalized verrucosis: a review of the associated diseases, evaluation, and treatments.
abstract: Generalized verrucosis has been described in the past as synonymous with epidermodysplasia verruciformis. It has been shown, however, that epidermodysplasia verruciformis and other genetic or immunodeficiency diseases are just a subset of diffuse infections with human papillomavirus termed "generalized verrucosis." This article defines generalized verrucosis and distinct diseases associated with generalized warts. The indications for histopathologic testing, human papillomavirus typing, and other laboratory analyses and potential treatment options are discussed.
authors.affiliation: Department of Dermatology, University of Maryland, Baltimore, Maryland 21201, USA.
authors.forename: Jennifer C
authors.initials: JC
authors.lastname: Sri
authors.forename: Meghan I
authors.initials: MI
authors.lastname: Dubina
authors.forename: Grace F
authors.initials: GF
authors.lastname: Kao
authors.forename: Peter L
authors.initials: PL
authors.lastname: Rady
authors.forename: Stephen K
authors.initials: SK
authors.lastname: Tyring
authors.forename: Anthony A
authors.initials: AA
authors.lastname: Gaspari
mesh_terms: D017074:Common Variable Immunodeficiency / Q000150:complications / Q000628:therapy / Q000821:virology; D015658:HIV Infections / Q000150:complications; D006801:Humans; D053306:Hyper-IgM Immunodeficiency Syndrome / Q000150:complications / Q000628:therapy / Q000821:virology; D007153:Immunologic Deficiency Syndromes / Q000150:complications / Q000628:therapy; D007165:Immunosuppression Therapy / Q000009:adverse effects; D027383:Papillomaviridae / Q000235:genetics; D030361:Papillomavirus Infections / Q000150:complications* / Q000628:therapy / Q000821:virology; D000081207:Primary Immunodeficiency Diseases; D016511:Severe Combined Immunodeficiency / Q000150:complications / Q000628:therapy / Q000821:virology; D018344:T-Lymphocytopenia, Idiopathic CD4-Positive / Q000150:complications / Q000628:therapy; D014860:Warts / Q000150:complications* / Q000628:therapy / Q000821:virology