title: Self-reported and parent-reported quality of life of children and adolescents with new-onset epilepsy.
abstract: OBJECTIVE
  To investigate the self-reported quality of life (QOL) of children and adolescents with new-onset epilepsy and explore parent's perceptions of their child's QOL and the impact of epilepsy on the family.
  
  
  METHODS
  As part of the Standard and New Antiepileptic Drug (SANAD) trial, 248 children (aged 8-15 years) with new-onset epilepsy and their parents completed batteries of QOL measures. Children completed the KINDL and subscales of the QOLIE-AD-48. Parental questionnaires included the Rutter Parent Scales, Adverse Events Profile, and subscales of the Child Health Questionnaire.
  
  
  RESULTS
  Compared with published norms, children with epilepsy had significantly poorer QOL across multiple domains compared with healthy children and children with asthma. Parents, particularly of younger children and those with other long-term health problems, were affected by their child's health or behavior, which affected their emotional well-being and time for their own needs.
  
  
  CONCLUSIONS
  Children with new-onset epilepsy, particularly those with comorbid conditions, are at risk of reduced QOL at the time of diagnosis. It is important that children with epilepsy and their families are assessed for psychosocial problems so that early intervention can be undertaken.
authors.affiliation: Division of Public Health Neurosciences Research Unit, University of Liverpool, Liverpool, United Kingdom.
authors.forename: Joanne
authors.initials: J
authors.lastname: Taylor
authors.forename: Ann
authors.initials: A
authors.lastname: Jacoby
authors.forename: Gus A
authors.initials: GA
authors.lastname: Baker
authors.forename: Anthony G
authors.initials: AG
authors.lastname: Marson
mesh_terms: D000293:Adolescent; D002648:Child; D003710:Demography; D004827:Epilepsy / Q000523:psychology*; D005192:Family Health; D005260:Female; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D008297:Male; D010290:Parents; D010465:Perception; D011788:Quality of Life; D057566:Self Report; D011795:Surveys and Questionnaires