title: 4-(4-Chloro-phen-yl)-6-hydr-oxy-5-(2-thienyl-carbonyl)-6-(trifluoro-meth-yl)-3,4,5,6-tetra-hydro-pyrimidin-2(1H)-one monohydrate.
abstract: The asymmetric unit of the title compound, C(16)H(12)ClF(3)N(2)O(3)S·H(2)O, contains two crystallographically independent organic mol-ecules and two water mol-ecules. The organic species are linked by an inter-molecular O-H⋯O hydrogen bond, while the water mol-ecules are connected to them through inter-molecular O-H⋯N hydrogen bonds. The thio-phene and phenyl rings are oriented at dihedral angles of 62.35 (4) in the first independent mol-ecule and 60.74 (5)° in the second, while the pyrimidine rings adopt twisted conformations in both molecules. Intra-molecular N-H⋯F inter-actions result in the formation of two five-membered rings having envelope conformations. In the crystal structure, further inter-molecular O-H⋯O and N-H⋯O hydrogen bonds link the mol-ecules into chains.
authors.affiliation: Department of Chemistry, Islamic Azad University, Yazd Branch, Yazd, Iran.
authors.forename: Mohammad Hossein
authors.initials: MH
authors.lastname: Mosslemin
authors.forename: Mohammad Reza
authors.initials: MR
authors.lastname: Nateghi
authors.forename: Hesamaddin
authors.initials: H
authors.lastname: Sadoughi
authors.forename: Asal
authors.initials: A
authors.lastname: Lamei