title: Fiber optic microendoscopy for preclinical study of bacterial infection dynamics.
abstract: We explore the use of fiber optic microendoscopy to image and quantify bacterial infection in the skin and lungs using an animal model. The contact probe fiber bundle fluorescence microendoscope has a 4 µm resolution, a 750 µm field of view, and a 1 mm outer diameter. Subcutaneous and intra-tracheal infections of fluorescent Mycobacterium bovis Bacillus Calmette-Guérin (BCG) bacteria were detected in situ from inocula down to 10(4) and 10(7) colony forming units, respectively.
authors.forename: Nooman
authors.initials: N
authors.lastname: Mufti
authors.forename: Ying
authors.initials: Y
authors.lastname: Kong
authors.forename: Jeffrey D
authors.initials: JD
authors.lastname: Cirillo
authors.forename: Kristen C
authors.initials: KC
authors.lastname: Maitland