title: Diffuse large B-cell lymphoma with oral manifestations.
abstract: Non-Hodgkin lymphomas (NHLs) are a heterogenic group of lymphoproliferative diseases with their different behavior pattern and response to treatments. As a Hodgkin disease, NHL occurs from lymphoid tissues and can spread to other organs. Prognosis depends on histologic type, grade, and treatment. In the World Health Organization classification, aggressive B-cell lymphomas are diffuse large B-cell lymphoma, Burkitt lymphoma/leukemia, and precursor lymphoblastic leukemia/lymphoma. They may present either nodal or extranodal disease, which may be either localized or disseminated. Diffuse large B-cell lymphoma is the most common type of lymphoma in adults and is clinically, morphologically, and genetically a heterogeneous group of malignant proliferations of mature B cells, too. Diffuse large B-cell lymphoma is the most common type of NHL and accounts for about 30% of the cases. In this clinical report, we evaluated clinically and histopathologically a 64-year-old male patient who had mild pain and edema in his mandibular premolar region, and the excisional biopsy showed diffuse large B-cell lymphoma.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Ondokuz Mayıs University, Samsun, Turkey.
authors.forename: Emel
authors.initials: E
authors.lastname: Bulut
authors.forename: Burak
authors.initials: B
authors.lastname: Bekçioğlu
authors.forename: Omer
authors.initials: O
authors.lastname: Günhan
authors.forename: Ismail
authors.initials: I
authors.lastname: Sener
mesh_terms: D000368:Aged; D001706:Biopsy; D017809:Fatal Outcome; D006801:Humans; D007150:Immunohistochemistry; D016403:Lymphoma, Large B-Cell, Diffuse / Q000473:pathology*; D008297:Male; D008339:Mandibular Neoplasms / Q000473:pathology*; D014057:Tomography, X-Ray Computed