title: Celebrating Professor Britton Chance (1913-2010), a founding father of redox sciences.
abstract: Renowned great scientist and redox pioneer, Dr. Britton Chance, closed his 97 years of legendary life on November 16, 2010. He was the Eldridge Reeves Johnson emeritus professor of biophysics, physical chemistry, and radiologic physics at the University of Pennsylvania. He achieved fame as a prominent biophysicist and developer of highly innovative biomedical instrumentation. His scientific career stretched over almost one century and he achieved many scientific and engineering breakthroughs throughout his long prolific career. The advances that he and his colleagues achieved led to great strides in our understanding of biology and disease. He was among the first scientists to recognize the importance of free radicals and reactive oxygen species in mitochondrial metabolism and cells as well as to map pathways of redox biology and signaling. Dr. Chance served as a pioneer and inspiration to generations of researchers in the fields of redox biochemistry, metabolism, and disease. He will be missed by all of us in the research community but will live on through his monumental scientific accomplishments, the novel instrumentation he developed, as well as the many scientists whom he trained and influenced.
authors.affiliation: Johnson Research Foundation, Department of Biochemistry and Biophysics, University of Pennsylvania Medical School , Philadelphia, Pennsylvania 19104-6059, USA. ohnishi@mail.med.upenn.edu
authors.forename: Tomoko
authors.initials: T
authors.lastname: Ohnishi
authors.forename: Jay L
authors.initials: JL
authors.lastname: Zweier
mesh_terms: D001703:Biophysics / Q000266:history*; D002627:Chemistry, Physical / Q000266:history*; D049673:History, 20th Century; D049674:History, 21st Century; D010084:Oxidation-Reduction; D010414:Pennsylvania