title: Metabolic homeostasis: HDACs take center stage.
abstract: Hormonal regulation of glucose and lipid metabolism is pivotal for metabolic homeostasis and energy balance. Two studies in this issue of Cell (Mihaylova et al., 2011 and Wang et al., 2011) introduce a new conserved signaling mechanism controlling catabolic gene expression: class IIa histone deacetylases (HDACs) regulate Foxo activity in Drosophila and mice.
authors.affiliation: Department of Biology, University of Rochester, River Campus Box 270211, Rochester, NY 14627, USA.
authors.forename: Jason
authors.initials: J
authors.lastname: Karpac
authors.forename: Heinrich
authors.initials: H
authors.lastname: Jasper