title: Preliminary evidence of within-subject changes in gray matter density associated with remission of bipolar depression.
abstract: A preliminary within-subjects MRI study of seven patients with a diagnosis of bipolar I disorder revealed that, compared to remission, depression was associated with gray matter density increases in subgenual prefrontal cortex, parahippocampal gyrus, and inferior temporal gyri. Decreases were observed in superior and inferior frontal gyri and anterior cingulate.
authors.affiliation: Semel Institute for Neuroscience and Human Behavior at UCLA, Los Angeles, CA 90024, USA. john.brooks@ucla.edu
authors.forename: John O
authors.initials: JO
authors.lastname: Brooks
authors.forename: Lara C
authors.initials: LC
authors.lastname: Foland-Ross
authors.forename: Paul M
authors.initials: PM
authors.lastname: Thompson
authors.forename: Lori L
authors.initials: LL
authors.lastname: Altshuler
mesh_terms: D000328:Adult; D001714:Bipolar Disorder / Q000473:pathology*; D001921:Brain / Q000473:pathology* / Q000503:physiopathology; D001931:Brain Mapping; D005260:Female; D006801:Humans; D021621:Imaging, Three-Dimensional; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D011569:Psychiatric Status Rating Scales