title: A wireless magnetoelastic sensor for urinary 2-naphthol detection based on the precipitation of 2-naphthol with diazonium salts.
abstract: A wireless magnetoelastic sensor has been developed for the determination of 2-naphthol (2-NAP) in human urine. This method is based on the precipitation of 2-NAP with diazonium salts produced by the diazo-reaction of sulfamethoxazole (SMZ) with nitrite under a weak alkaline condition, resulting in a descending of the resonance frequency of a wireless magnetoelastic sensor. The frequence shift values (ΔF) of the sensor were directly proportional to the concentration in the range of 1.13 - 139 µmol L(-1) for 2-NAP with a correlation coefficient of 0.997 and a detection limit of 0.340 µmol L(-1). The relative standard deviations were 2.38, 2.40 and 2.44%, and the average recovery was 107% (n = 6). The proposed method has additional advantages of being less time-consuming, low cost and remote query, and can be applied for real-time and in situ monitoring of 2-NAP in human urine. It would be a benefit to extend the scope of applications of magnetoelastic sensing techniques.
authors.affiliation: College of Public Health, University of South China, Hengyang, PR China.
authors.forename: Yu-Kun
authors.initials: YK
authors.lastname: Yuan
authors.forename: Yong-Sheng
authors.initials: YS
authors.lastname: Wang
authors.forename: Xi-Lin
authors.initials: XL
authors.lastname: Xiao
authors.forename: Jin-Hua
authors.initials: JH
authors.lastname: Xue
authors.forename: Gui-Rong
authors.initials: GR
authors.lastname: Li
authors.forename: Rong-Hui
authors.initials: RH
authors.lastname: Kang
authors.forename: Jin-Quan
authors.initials: JQ
authors.lastname: Zhang
authors.forename: Lin-Fei
authors.initials: LF
authors.lastname: Shi
mesh_terms: D001391:Azo Compounds / Q000737:chemistry*; D015374:Biosensing Techniques / Q000295:instrumentation*; D004548:Elasticity; D006801:Humans; D008280:Magnetics; D015394:Molecular Structure; D009284:Naphthols / Q000652:urine*; D012492:Salts / Q000737:chemistry; D012680:Sensitivity and Specificity
chemical_list: D001391:Azo Compounds; D009284:Naphthols; D012492:Salts; C028405:2-naphthol