title: [Cyclic episodes of confusion and movement disorders: consider hyopglycemia and insulinoma].
abstract: Insulinomas are rare neuroendocrine tumours of the pancreas which present with neuroglycopenic and autonomic symptoms induced by hypoglycemic periods. The onset is insidious. Because of atypical symptoms like temporary movement disorders and behavioural disturbances the diagnosis is often made at a late stage. We describe two patients with cyclic behavioural and movement disorders caused by already present but not recognised insulinomas. The treatment options are discussed, in which the most common surgical therapy is not always a first choice in elderly patients with comorbidity. With drug therapy patients can be free of symptoms for a longer period without any significant complications.
authors.affiliation: Klinisch geriater, TweeSteden ziekenhuis Tilburg. cverschoor@tsz.nl
authors.forename: C J
authors.initials: CJ
authors.lastname: Verschoor
authors.forename: W A
authors.initials: WA
authors.lastname: Oranje
authors.forename: H A A M
authors.initials: HA
authors.lastname: Maas
mesh_terms: D000368:Aged; D003221:Confusion / Q000175:diagnosis / Q000209:etiology*; D005260:Female; D006801:Humans; D007003:Hypoglycemia / Q000150:complications* / Q000175:diagnosis; D007340:Insulinoma / Q000150:complications* / Q000175:diagnosis; D009069:Movement Disorders / Q000175:diagnosis / Q000209:etiology*; D010190:Pancreatic Neoplasms / Q000150:complications* / Q000175:diagnosis