title: Are there estrogen-receptors in human laryngeal cancers.
abstract: The presence of estrogen receptors in laryngeal carcinoma is controversial; with two independent methods (testing the binding of monoclonal antibodies against receptor protein by immunohistochemistry binding of labelled H-3-estradiol with the charcoal-dextran method), the levels of ER were found to be, if any, extremely low and without correlation to age, sex and previous radiation therapy of the patient. Administration of antiestrogens (if rationalized by the presence of ER) is therefore not indicated.
authors.affiliation: UNIV TORONTO,DEPT OTOLARYNGOL HEAD & NECK SURG,TORONTO M5S 1A1,ONTARIO,CANADA. ST JOSEPHS HLTH CTR,DEPT PATHOL,LONDON,ON,CANADA. PRINCESS MARGARET HOSP,DEPT PATHOL,TORONTO M4X 1K9,ONTARIO,CANADA. UNIV TORONTO,DEPT CLIN BIOCHEM,TORONTO M5S 1A1,ONTARIO,CANADA.
authors.forename: R
authors.initials: R
authors.lastname: Ng
authors.forename: P
authors.initials: P
authors.lastname: Gullane
authors.forename: C
authors.initials: C
authors.lastname: Crukley
authors.forename: D
authors.initials: D
authors.lastname: Banerjee
authors.forename: J
authors.initials: J
authors.lastname: Kellen