title: Potassium tert-butoxide promoted intramolecular arylation via a radical pathway.
abstract: Potassium tert-butoxide mediated intramolecular cyclization of aryl ethers, amines, and amides was efficiently performed under microwave irradiation to provide the corresponding products in high regioisomeric ratios. The reaction proceeds via single-electron transfer to initiate the formation of an aryl radical, followed by a kinetically favored 5-exo-trig and subsequent ring expansion.
authors.affiliation: Department of Chemistry, Université de Montréal, Box 6128, Station Downtown, Montréal, Québec, Canada H3C 3J7.
authors.forename: Daniela Sustac
authors.initials: DS
authors.lastname: Roman
authors.forename: Yoko
authors.initials: Y
authors.lastname: Takahashi
authors.forename: André B
authors.initials: AB
authors.lastname: Charette