title: Candida spp. prevalence in well controlled type 2 diabetic patients with denture stomatitis.
abstract: OBJECTIVE
  The aim of this study was to compare the prevalence of Candida spp. in diabetics and nondiabetics with and without denture stomatitis (DS).
  
  
  METHODS
  Mycologic samples were taken from the dentures of 90 healthy subjects (control group [CG]), 80 denture stomatitis nondiabetics (DSND), and 40 denture stomatitis diabetics (DSD; well controlled type 2) for identification of Candida spp. Results were analyzed by Fisher exact test, Bonferroni-corrected confidence interval, and χ(2) test (α = .05).
  
  
  RESULTS
  Candida albicans was the predominant species isolated (81.9%; P < .016), with C. tropicalis and C. glabrata demonstrating similar prevalence (15.71% and 15.24%, respectively). The prevalence of C. albicans and C. tropicalis in the DS groups were significantly higher (P < .01) than in the CG. The prevalence of C. tropicalis significantly increased with the highest degree of inflammation (P < .05).
  
  
  CONCLUSIONS
  The prevalence of Candida spp. was similar between diabetic and nondiabetic patients with DS. Candida tropicalis may play a role in the progression of DS.
authors.affiliation: Araraquara Dental School, UNESP - Univ Estadual Paulista, Araraquara, São Paulo, Brazil.
authors.forename: Paula Volpato
authors.initials: PV
authors.lastname: Sanitá
authors.forename: Ana Cláudia
authors.initials: AC
authors.lastname: Pavarina
authors.forename: Eunice Teresinha
authors.initials: ET
authors.lastname: Giampaolo
authors.forename: Mariana Montenegro
authors.initials: MM
authors.lastname: Silva
authors.forename: Ewerton Garcia de Oliveira
authors.initials: EG
authors.lastname: Mima
authors.forename: Daniela Garcia
authors.initials: DG
authors.lastname: Ribeiro
authors.forename: Carlos Eduardo
authors.initials: CE
authors.lastname: Vergani
mesh_terms: D000368:Aged; D001786:Blood Glucose / Q000378:metabolism; D002175:Candida / Q000145:classification / Q000302:isolation & purification*; D016022:Case-Control Studies; D016009:Chi-Square Distribution; D003430:Cross-Sectional Studies; D017266:Dental Prosthesis / Q000009:adverse effects / Q000382:microbiology*; D003778:Dentures / Q000009:adverse effects*; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000150:complications / Q000382:microbiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009055:Mouth / Q000382:microbiology; D012016:Reference Values; D012737:Sex Factors; D018709:Statistics, Nonparametric; D013282:Stomatitis, Denture / Q000097:blood / Q000150:complications / Q000382:microbiology*
chemical_list: D001786:Blood Glucose