title: Changes in executive function after acute bouts of passive cycling in Parkinson's disease.
abstract: Individuals with Parkinson's disease (PD) often experience cognitive declines. Although pharmacologic therapies are helpful in treating motor deficits in PD, they do not appear to be effective for cognitive complications. Acute bouts of moderate aerobic exercise have been shown to improve cognitive function in healthy adults. However, individuals with PD often have difficulty with exercise. This study examined the effects of passive leg cycling on executive function in PD. Executive function was assessed with Trail-Making Test (TMT) A and B before and after passive leg cycling. Significant improvements on the TMT-B test occurred after passive leg cycling. Furthermore, the difference between times to complete the TMT-B and TMT-A significantly decreased from precycling to postcycling. Improved executive function after passive cycling may be a result of increases in cerebral blood flow. These findings suggest that passive exercise could be a concurrent therapy for cognitive decline in PD.
authors.affiliation: Dept. of Exercise Physiology, Kent State University, Kent, OH, USA.
authors.forename: Angela L
authors.initials: AL
authors.lastname: Ridgel
authors.forename: Chul-Ho
authors.initials: CH
authors.lastname: Kim
authors.forename: Emily J
authors.initials: EJ
authors.lastname: Fickes
authors.forename: Matthew D
authors.initials: MD
authors.lastname: Muller
authors.forename: Jay L
authors.initials: JL
authors.lastname: Alberts
mesh_terms: D000328:Adult; D000368:Aged; D000375:Aging / Q000502:physiology; D000704:Analysis of Variance; D002560:Cerebrovascular Circulation; D018592:Cross-Over Studies; D056344:Executive Function / Q000502:physiology*; D005081:Exercise Therapy / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D010300:Parkinson Disease / Q000503:physiopathology / Q000523:psychology* / Q000628:therapy*; D010809:Physical Fitness / Q000502:physiology; D014145:Trail Making Test; D016896:Treatment Outcome