title: Correlations of PCBs, DIOXIN, and PBDE with TSH in children's blood in areas of computer E-waste recycling.
abstract: OBJECTIVE
  To study correlations of polychlorinated biphenyls (PCBs), DIOXIN, and polybrominated diphenyl ethers (PBDE) with thyroid stimulating hormone(TSH) in children, and assess the impact on children's health.
  
  
  METHODS
  Three hundred and sixty nine children aged from 6 to 8, including 195 from Luqiao, the computer E-waste recycling area, and 174 from Longyou, the control area, were selected for this investigation to elucidate the correlation of PCBs, DIOXIN, and PBDE with TSH in children's blood samples. The children had a physical examination and their blood levels of PCBs, DIOXIN, PBDE, and TSH were detected after sample collection.
  
  
  RESULTS
  In the E-waste recycling area, the contents of PCBs, PBDE, DIOXIN, and TSH in the blood samples of children were 484.00 ± 84.86 ng·g(-1) lipid weight, 664.28 ± 262.38 ng·g(-1) lipid weight, 26.00 ± 19.58 ng·g(-1) lipid weight and 1.88 ± 0.42 μIU/mL (serum) respectively, while in the control area, the PCBs, PBDE, DIOXIN, and TSH contents were 255.38 ± 95 ng·g(-1) lipid weight, 375.81 ± 262.43 ng·g(-1) lipid weight, 39.64 ± 31.86 ng·g(-1) lipid weight, and 3.31±1.04 μIU/mL respectively.
  
  
  CONCLUSIONS
  The health status of children in the control area are better than that in the contaminated area. Among children who are exposed to persistent organic pollutants, the pollutant content increases significantly in their serum, and the distribution of TSH levels in their bodies are also affected.
authors.affiliation: Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, Zhejiang, China.
authors.forename: GuanGen
authors.initials: G
authors.lastname: Han
authors.forename: GangQiang
authors.initials: G
authors.lastname: Ding
authors.forename: XiaoMing
authors.initials: X
authors.lastname: Lou
authors.forename: XiaoFeng
authors.initials: X
authors.lastname: Wang
authors.forename: JianLong
authors.initials: J
authors.lastname: Han
authors.forename: HaiTao
authors.initials: H
authors.lastname: Shen
authors.forename: Yu
authors.initials: Y
authors.lastname: Zhou
authors.forename: LeYan
authors.initials: L
authors.lastname: Du
mesh_terms: D002648:Child; D002681:China; D004147:Dioxins / Q000097:blood* / Q000737:chemistry; D059029:Electronic Waste; D004785:Environmental Pollutants / Q000097:blood* / Q000737:chemistry; D005260:Female; D055768:Halogenated Diphenyl Ethers / Q000097:blood* / Q000737:chemistry; D006801:Humans; D008297:Male; D011078:Polychlorinated Biphenyls / Q000097:blood* / Q000737:chemistry; D059027:Recycling; D012037:Refuse Disposal / Q000379:methods; D013972:Thyrotropin / Q000097:blood*
chemical_list: D004147:Dioxins; D004785:Environmental Pollutants; D055768:Halogenated Diphenyl Ethers; C086401:pentabromodiphenyl ether; D013972:Thyrotropin; D011078:Polychlorinated Biphenyls