title: Dissemination of blaKPC-2 by the spread of Klebsiella pneumoniae clonal complex 258 clones (ST258, ST11, ST437) and plasmids (IncFII, IncN, IncL/M) among Enterobacteriaceae species in Brazil.
abstract: This article reports the spread of bla(KPC-2) in the Sao Paulo and Rio de Janeiro states, facilitated by globally spread K. pneumoniae clonal complex 258 (CC258) clones (ST258, ST11, and ST437) and a diversity of plasmids (IncFII, IncN, and IncL/M, two untypeable plasmids carrying Tn4401a or Tn4401b) successfully disseminated among species of the Enterobacteriaceae (Enterobacter cloacae, Serratia marcescens, and Citrobacter freundii). It also constitutes the first description of sequence type 258 (ST258) in Brazil, which was associated with a nosocomial hospital outbreak in Ribeirao Preto city.
authors.affiliation: Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, Ribeirao Preto, Brazil.
authors.forename: Leonardo Neves
authors.initials: LN
authors.lastname: Andrade
authors.forename: Tânia
authors.initials: T
authors.lastname: Curiao
authors.forename: Joseane Cristina
authors.initials: JC
authors.lastname: Ferreira
authors.forename: Juliana Mucedola
authors.initials: JM
authors.lastname: Longo
authors.forename: Eduardo Carneiro
authors.initials: EC
authors.lastname: Clímaco
authors.forename: Roberto
authors.initials: R
authors.lastname: Martinez
authors.forename: Fernando
authors.initials: F
authors.lastname: Bellissimo-Rodrigues
authors.forename: Aníbal
authors.initials: A
authors.lastname: Basile-Filho
authors.forename: Marco Antônio
authors.initials: MA
authors.lastname: Evaristo
authors.forename: Pedro F
authors.initials: PF
authors.lastname: Del Peloso
authors.forename: Vanessa Bley
authors.initials: VB
authors.lastname: Ribeiro
authors.forename: Afonso Luis
authors.initials: AL
authors.lastname: Barth
authors.forename: Milena Cristina
authors.initials: MC
authors.lastname: Paula
authors.forename: Fernando
authors.initials: F
authors.lastname: Baquero
authors.forename: Rafael
authors.initials: R
authors.lastname: Cantón
authors.forename: Ana Lúcia da Costa
authors.initials: AL
authors.lastname: Darini
authors.forename: Teresa M
authors.initials: TM
authors.lastname: Coque
mesh_terms: D001938:Brazil; D004755:Enterobacteriaceae / Q000201:enzymology* / Q000235:genetics; D005843:Geography; D007711:Klebsiella pneumoniae / Q000201:enzymology* / Q000235:genetics; D010957:Plasmids; D001618:beta-Lactamases / Q000235:genetics*
chemical_list: C491478:beta-lactamase KPC-2; D001618:beta-Lactamases