title: Biomimetic mussel adhesive inspired clickable anchors applied to the functionalization of fe(3) o(4) nanoparticles.
abstract: The functionalization of magnetite (Fe(3) O(4) ) nanoparticles with dopamine-derived clickable biomimetic anchors is reported. Herein, an alkyne-modified catechol-derivative is employed as the anchor, as i) the catechol-functional anchor groups possess irreversible covalent binding affinity to Fe(3) O(4) nanoparticles, and ii) the alkyne terminus enables further functionalization of the nanoparticles by the grafting-onto approach with various possibilities offered by 'click' chemistry. In the present work, azido-end group functionalized Rhodamine and poly(ethylene glycol) (PEG) are utilized to coat the iron oxide nanoparticles to make them fluorescent and water soluble.
authors.affiliation: Makromolekulare Chemie II and Bayreuther Zentrum für Kolloide und Grenzflächen, Universität Bayreuth, 95440 Bayreuth, Germany.
authors.forename: Anja S
authors.initials: AS
authors.lastname: Goldmann
authors.forename: Christine
authors.initials: C
authors.lastname: Schödel
authors.forename: Andreas
authors.initials: A
authors.lastname: Walther
authors.forename: Jiayin
authors.initials: J
authors.lastname: Yuan
authors.forename: Katja
authors.initials: K
authors.lastname: Loos
authors.forename: Axel H E
authors.initials: AH
authors.lastname: Müller