title: Multiple radiculopathy as the presenting manifestation of primary spinal leptomeningeal B cell lymphoma detected by flow cytometry of cerebrospinal fluid.
abstract: Primary leptomeningeal lymphoma is a rare syndrome characterized by lymphomatous meningeal infiltration without identification of systemic lymphoma or parenchymal central nervous system lymphoma. We report a case of a 62-year-old immunocompetent woman with primary spinal leptomeningeal lymphoma presenting as cervical and lumbar radiculopathy who is rare because of particularly unusual onset site of B cell lymphoma. Interestingly, the diagnosis was possible only by cerebrospinal fluid flow cytometry.
authors.affiliation: Department of Neurological, Neuropsychological, Morphological and Movement Sciences, Policlinico G. Rossi, University of Verona, Italy, Piazzale L.A. Scuro 10, 37134 Verona, Italy. manuel_cappellari@libero.it
authors.forename: Manuel
authors.initials: M
authors.lastname: Cappellari
authors.forename: Fabio
authors.initials: F
authors.lastname: Benedetti
authors.forename: Antonio
authors.initials: A
authors.lastname: Fiaschi
authors.forename: Maria Donata
authors.initials: MD
authors.lastname: Benedetti
mesh_terms: D015703:Antigens, CD / Q000378:metabolism; D002555:Cerebrospinal Fluid; D005260:Female; D005434:Flow Cytometry / Q000379:methods; D006801:Humans; D007121:Immunocompetence; D016393:Lymphoma, B-Cell / Q000134:cerebrospinal fluid / Q000150:complications*; D008577:Meningeal Neoplasms / Q000134:cerebrospinal fluid / Q000150:complications*; D008875:Middle Aged; D011843:Radiculopathy / Q000175:diagnosis* / Q000209:etiology*
chemical_list: D015703:Antigens, CD