title: Eye-related visual hallucinations: consider 'Charles Bonnet syndrome'.
abstract: The Charles Bonnet Syndrome (CBS) is typically characterized by visual hallucinations in elderly people without cognitive defects. This article presents the case of an 80-year-old male patient with a one-year history of visual hallucinations, secondary to glaucoma, in both eyes. Neither a dopamine agonist nor cholinesterase inhibitor therapy improved his symptoms. In this case, the hallucinations were gradually improved after administration of a GABAergic drug, pregabalin, for diabetic polyneuropathy. Placebo-controlled clinical trials would be needed to support this effect of pregabalin, as suggested by this association.
authors.affiliation: Department of Neurology, Faculty of Medicine, Maltepe University, Istanbul, Turkey. cinarnilgun@gmail.com
authors.forename: Nilgun
authors.initials: N
authors.lastname: Cinar
authors.forename: Sevki
authors.initials: S
authors.lastname: Sahin
authors.forename: Sibel
authors.initials: S
authors.lastname: Karsidag
mesh_terms: D000369:Aged, 80 and over; D000700:Analgesics / Q000627:therapeutic use; D003929:Diabetic Neuropathies / Q000150:complications / Q000188:drug therapy; D005901:Glaucoma / Q000150:complications*; D006212:Hallucinations / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology*; D006801:Humans; D008297:Male; D000069583:Pregabalin; D012720:Severity of Illness Index; D013577:Syndrome; D014786:Vision Disorders / Q000209:etiology / Q000503:physiopathology; D005680:gamma-Aminobutyric Acid / Q000031:analogs & derivatives / Q000627:therapeutic use
chemical_list: D000700:Analgesics; D000069583:Pregabalin; D005680:gamma-Aminobutyric Acid