title: Nanofibers Self-assembled from Structural Complementary Borono-decapeptides.
abstract: A series of structural complementary decapeptides with phenyl boronic acid tails or borono-decapeptides (BPs) were designed and synthesized for supramolecular self-assembly. After dissolving these borono-decapeptides in deionized (DI) water, well-defined nanofibers were formed in BP1 (B(OH)(2) VEKELVKEKL-OH) and BP3 (B(OH)(2) AELELARARL-OH). It was found that the self-assembled borono-decapeptide BP1 and BP3 have a parallel β-sheet conformation in the formed nanofibers. The strategy demonstrated here shows a great prospect in preparation of well-ordered nanofibers via rationally designing the molecular structures of peptides.
authors.affiliation: Key Laboratory of Biomedical Polymers of Ministry of Education & Department of Chemistry, Wuhan University, Wuhan 430072, P. R. China.
authors.forename: Chang-Sheng
authors.initials: CS
authors.lastname: Chen
authors.forename: Tian-Jiao
authors.initials: TJ
authors.lastname: Ji
authors.forename: Xiao-Ding
authors.initials: XD
authors.lastname: Xu
authors.forename: Xian-Zheng
authors.initials: XZ
authors.lastname: Zhang
authors.forename: Ren-Xi
authors.initials: RX
authors.lastname: Zhuo