title: Bilateral middle cerebral artery thromboembolic occlusion. Could maternal hyperthermia be a detrimental factor?
abstract: We describe a six-month-old girl with microcephaly, developmental delay, truncal hypotonia, left pyramidal signs, partial seizures and myoclonic spasms, born to a feverish mother. MRI showed bilateral vascular lesions in the territory of the middle cerebral arteries, prevalent in the right hemisphere, together with hypoplasia of the posterior part of the corpus callosum and Wallerian degeneration of the cerebral peduncle. There may be many reasons for these lesions. In the reported patient the presence of maternal hyperthermia could have exacerbated cerebral thromboembolic occlusion.
authors.affiliation: Pediatric Neurology Division, Department of Pediatrics, La Sapienza University 1, Rome, Italy. childneurology.sapienzaroma@live.it
authors.forename: Alberto
authors.initials: A
authors.lastname: Spalice
authors.forename: Francesca
authors.initials: F
authors.lastname: Del Balzo
authors.forename: Laura
authors.initials: L
authors.lastname: Papetti
authors.forename: Francesco
authors.initials: F
authors.lastname: Nicita
authors.forename: Fabiana
authors.initials: F
authors.lastname: Ursitti
authors.forename: Guglielmo
authors.initials: G
authors.lastname: Salvatori
authors.forename: Paola
authors.initials: P
authors.lastname: Iannetti
mesh_terms: D000015:Abnormalities, Multiple / Q000209:etiology*; D002539:Cerebral Arterial Diseases / Q000209:etiology* / Q000473:pathology; D002648:Child; D005260:Female; D005334:Fever / Q000150:complications*; D006801:Humans; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D013923:Thromboembolism / Q000209:etiology*