title: Prediction of disease causing gene in Xq22.1 region of human X-chromosome.
abstract: A comprehensive analysis of the X-chromosome led to the discovery of an important region found to be Xq22.1. Xq22.1 was analysed in detail to locate a credible gene carrying segment on it, which may be implicated in various disorders related to the X-chromosome. Finding genes in a genomic sequence is a fiddly problem. Hence, we developed a new in-silico approach to identify the novel gene, based on homology methods (extrinsic methods) and gene prediction methods (intrinsic methods).
authors.affiliation: Department of Bioinformatics, Outsource Bioinformatics, Development Center, Grand Residency, Bangalore, India. vidyaniranjan.bioinfo@gmail.com
authors.forename: Vidya
authors.initials: V
authors.lastname: Niranjan
authors.forename: Riaz
authors.initials: R
authors.lastname: Ahmed
authors.forename: R
authors.initials: R
authors.lastname: Seenivasagam
authors.forename: G
authors.initials: G
authors.lastname: Sivakumar
mesh_terms: D001483:Base Sequence; D002874:Chromosome Mapping; D041321:Chromosomes, Human, X / Q000235:genetics*; D005796:Genes; D015894:Genome, Human; D023281:Genomics / Q000379:methods*; D006801:Humans; D008969:Molecular Sequence Data; D025064:Sex Chromosome Disorders / Q000235:genetics*