title: Lantana montevidensis Briq improves the aminoglycoside activity against multiresistant Escherichia coli and Staphylococcus aureus.
abstract: OBJECTIVE
  In this work, we report the antibacterial and modulatory activity of Lantana montevidensis Briq.
  
  
  METHODS
  The antibacterial activities of leaf (LELm) and root (RELm) extracts alone or in association with aminoglycosides were determined by a microdilution test. Multiresistant strains of Escherichia coli (Ec 27) and Staphylococcus aureus (Sa 358) were used.
  
  
  RESULTS
  The results show the inhibitory activity of LELm against E. coli (minimal inhibitory concentration [MIC] 16 μg/mL) and S. aureus (MIC 128 μg/mL). The synergistic effect of the extracts and aminoglycosides was verified too. The maximum effects were obtained with RELm with gentamicin against E. coli with MIC reduction (312 to 2 μL).
  
  
  CONCLUSIONS
  The data from this study are indicative of the activity antibacterial of extracts of L. montevidensis and its potential in modifying the resistance of aminoglycosides.
authors.affiliation: Vice-Reitoria de Pesquisa e Pós-Gradução, Universidade de Fortaleza, Av. Washington Soares 1321, Edson Queiroz, 60811-905, Fortaleza-CE, Brasil.
authors.forename: Erlanio O
authors.initials: EO
authors.lastname: Sousa
authors.forename: Thiago S
authors.initials: TS
authors.lastname: Almeida
authors.forename: Fabíola F G
authors.initials: FF
authors.lastname: Rodrigues
authors.forename: Adriana R
authors.initials: AR
authors.lastname: Campos
authors.forename: Sidney G
authors.initials: SG
authors.lastname: Lima
authors.forename: José G M
authors.initials: JG
authors.lastname: Costa