title: 16α,17α-Ep-oxy-5α-hydr-oxy-6β-nitrooxy-20-oxopregnan-3β-yl acetate.
abstract: The title steroid, C(23)H(33)NO(8), is a pregnane derivative obtained regio-, stereo- and chemoselectively from the ring opening of the corresponding 5α,6α;16α,17α-diepoxide with bis-muth(III) nitrate. There are two symmetry-independent mol-ecules in the asymmetric unit that show no significant differences concerning bond lengths and angles. All rings are trans-fused. The conformations of the six-membered rings are close to chair forms, while the five-membered ring adopts an envelope conformation. The mol-ecules are held together by an extensive O-H⋯O hydrogen-bonding network of chains runnning along the a axis.
authors.forename: R M A
authors.initials: RM
authors.lastname: Pinto
authors.forename: A
authors.initials: A
authors.lastname: Matos Beja
authors.forename: J A R
authors.initials: JA
authors.lastname: Salvador
authors.forename: J A
authors.initials: JA
authors.lastname: Paixão