title: (S)-1-[3,5-Bis-(trifluoro-meth-yl)phen-yl]-N-methylethyl-amine-(R)-2-hydroxy-butane-dioic acid (1/1).
abstract: In the title compound, C(11)H(11)F(6)N·C(4)H(6)O(5), a key inter-mediate in the synthesis of the NK1 receptor antagonist of casopitant, the F atoms of the trifluoro-methyl groups are disordered over two sites with equal occupancies. In the crystal, the components are linked by bifurcated N-H⋯(O,O) hydrogen bonds.
authors.affiliation: School of Chemistry and Chemical Engineering, Southeast University, Nanjing, People's Republic of China.
authors.forename: Hai-Bin
authors.initials: HB
authors.lastname: Zhu
authors.forename: Jun-Feng
authors.initials: JF
authors.lastname: Ji
authors.forename: Hai
authors.initials: H
authors.lastname: Wang