title: Methyl 2-methyl-4-(oxiran-2-ylmeth-oxy)-2H-1,2-benzothia-zine-3-carboxyl-ate 1,1-dioxide.
abstract: In the title compound, C(14)H(15)NO(6)S, the thia-zine ring adopts a distorted half-chair conformation. The structure displays several cooperative weak inter-molecular C-H⋯O hydrogen-bonding inter-actions, giving rise to a two-dimensional sheet packing motif. The CH(2) group in the meth-oxy linker to the oxirane ring, and the CH group in that ring, exhibit twofold positional disorder. The three-membered oxirane ring is twisted approximately perpendicular with respect to thia-zine ring (dihedral angle = 60/86° for the major/minor disorder components). 1,2-Benzothia-zines of this kind have a wide range of biological activities and are mainly used as medicines in the treatment of inflammation and rheumatoid arthritis.
authors.forename: Matloob
authors.initials: M
authors.lastname: Ahmad
authors.forename: Hamid Latif
authors.initials: HL
authors.lastname: Siddiqui
authors.forename: Muhammad
authors.initials: M
authors.lastname: Zia-Ur-Rehman
authors.forename: Mark R J
authors.initials: MR
authors.lastname: Elsegood
authors.forename: George W
authors.initials: GW
authors.lastname: Weaver