title: [Study on subtype of human papillomavirus infection among aged 25 - 54 reproductive women in Beijing from 2006 to 2008].
abstract: OBJECTIVE
  To investigate subtype of HPV infection among women at age of 25 to 54 years in Beijing.
  
  
  METHODS
  From Sept. 2006 to Dec. 2008, 5552 reproductive women at age of 25 to 54 years classified into each 5-year as group were screened. Each participant completed a questionnaire and a sample of exfoliated cervical cells for liquid-based cytology and HPV subtype gene testing was performed.
  
  
  RESULTS
  The overall prevalence of HPV was 6.68% (371/5552). High-risk HPV and Low-risk HPV prevalence were 5.76% (320/5552) and 2.00% (111/5552), respectively. The most common HPV types were HPV16 (2.61%, 145/5552), HPV58 (0.97%, 54/5552), HPV33 (0.85%, 47/5552), HPV43 (0.74%, 41/5552) and HPV56 (0.70%, 39/5552). There were two peaks of HPV prevalence: groups of 30 - 34 years and 40 - 44 years.
  
  
  CONCLUSIONS
  The most common HPV subtypes in Beijing were HPV 16, 58, 33 and 43 and HPV prevalence showed a bi-modal age-specific curve.
authors.affiliation: Department of Gynecology, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing 100026, China.
authors.forename: Rong
authors.initials: R
authors.lastname: Zhao
authors.forename: Wei-yuan
authors.initials: WY
authors.lastname: Zhang
authors.forename: Song-wen
authors.initials: SW
authors.lastname: Zhang
authors.forename: Ming-hui
authors.initials: MH
authors.lastname: Wu
authors.forename: Jian-dong
authors.initials: JD
authors.lastname: Wang
authors.forename: Zheng
authors.initials: Z
authors.lastname: Xie
authors.forename: Jing
authors.initials: J
authors.lastname: Feng
authors.forename: Jing
authors.initials: J
authors.lastname: Pan
authors.forename: Jun-hua
authors.initials: JH
authors.lastname: Wang
authors.forename: Xin-zhi
authors.initials: XZ
authors.lastname: Liu
mesh_terms: D000328:Adult; D017677:Age Distribution; D000367:Age Factors; D002681:China / Q000453:epidemiology; D003430:Cross-Sectional Studies; D055088:Early Detection of Cancer; D005260:Female; D006801:Humans; D008875:Middle Aged; D020411:Oligonucleotide Array Sequence Analysis; D027383:Papillomaviridae / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification*; D030361:Papillomavirus Infections / Q000453:epidemiology* / Q000821:virology; D015995:Prevalence; D012307:Risk Factors; D011795:Surveys and Questionnaires; D002583:Uterine Cervical Neoplasms / Q000209:etiology / Q000517:prevention & control* / Q000821:virology; D014626:Vaginal Smears