title: CURVES+ web server for analyzing and visualizing the helical, backbone and groove parameters of nucleic acid structures.
abstract: Curves+, a revised version of the Curves software for analyzing the conformation of nucleic acid structures, is now available as a web server. This version, which can be freely accessed at http://gbio-pbil.ibcp.fr/cgi/Curves_plus/, allows the user to upload a nucleic acid structure file, choose the nucleotides to be analyzed and after optionally setting a number of input variables, view the numerical and graphic results online or download files containing a set of helical, backbone and groove parameters that fully describe the structure. PDB format files are also provided for offline visualization of the helical axis and groove geometry.
authors.affiliation: Université Lyon 1, CNRS, UMR 5086, Bases Moléculaires et Structurales des Systèmes Infectieux, IBCP FR3302, 7 passage du Vercors, F-69367, France.
authors.forename: Christophe
authors.initials: C
authors.lastname: Blanchet
authors.forename: Marco
authors.initials: M
authors.lastname: Pasi
authors.forename: Krystyna
authors.initials: K
authors.lastname: Zakrzewska
authors.forename: Richard
authors.initials: R
authors.lastname: Lavery
mesh_terms: D000465:Algorithms; D020029:Base Pairing; D009690:Nucleic Acid Conformation; D012984:Software; D014584:User-Computer Interface