title: (1R,3S,5R,6S)-6-Hydr-oxy-3-tosyl-oxy-tropan-8-ium chloride.
abstract: The title compound, C(15)H(22)NO(4)S(+)·Cl(-), is a hydrolysis product of lesatropane [(1R,3S,5R,6S)-6-acet-oxy-3-tosyl-oxytropane] hydro-chloride, a potential anti-glaucoma agent. As in lesatropane, the piperidine and pyrrolidine rings in the title compound adopt chair and envelope conformations, respectively. There are two mol-ecules in the unit cell with similar conformations. The crystal structure is stabilized by inter-molecular O-H⋯Cl and N-H⋯Cl hydrogen bonds.
authors.affiliation: Department of Pharmacy, Shanghai Jiao Tong University School of Medicine, South Chongqing Road 280, Shanghai 200025, People's Republic of China.
authors.forename: Nian-Xi
authors.initials: NX
authors.lastname: Yu
authors.forename: Li-Min
authors.initials: LM
authors.lastname: Yang
authors.forename: Yang
authors.initials: Y
authors.lastname: Lu