title: [Clinical trial of cellulose in treatment of functional constipation in children].
abstract: OBJECTIVE
  To study the efficacy and safety of cellulose for the treatment of functional constipation in children.
  
  
  METHODS
  A prospective, self-controlled, clinical trial using cellulose was conducted for 2 weeks in 34 children with functional constipation. The constipation symptoms and the characteristics of feces after the treatment were observed.
  
  
  RESULTS
  The characteristics of feces and the constipation symptoms were improved significantly after the treatment. The total efficacy rate was 37% 3 days after treatment, 87% 7 days after treatment and 90% 14 days after treatment. The satisfactory rates of doctors and children's parents on the therapeutic effects were 57% and 63%, respectively. No adverse events, such as abdominal distention, pain or diarrhea, were observed during the treatment.
  
  
  CONCLUSIONS
  Cellulose is effective and safe in the treatment of functional constipation in children.
authors.affiliation: Children's Hospital of Fudan University, Shanghai 201102, China.
authors.forename: Jun-Ping
authors.initials: JP
authors.lastname: Lu
authors.forename: Ying
authors.initials: Y
authors.lastname: Huang
authors.forename: Ye
authors.initials: Y
authors.lastname: Zhang
authors.forename: Xiao-Hui
authors.initials: XH
authors.lastname: Wang
authors.forename: Cai-Hong
authors.initials: CH
authors.lastname: Shao
mesh_terms: D002482:Cellulose / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D003248:Constipation / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D011446:Prospective Studies
chemical_list: D002482:Cellulose