title: [A case of angiosarcoma of the scalp with severe fluid retention after administering docetaxel].
abstract: A 7 3-year-old man with angiosarcoma was treated with concurrent chemoradiotherapy, using docetaxel (25mg/m(2) weekly). While the size of the tumor reduced rapidly, fluid retention, considered as an adverse effect of docetaxel, appeared at the cumulative dose of 325mg/m(2). He required chest drainage for prolonged pleural effusion. Though fluid retention due to docetaxel is infrequently reported in Japan, it may lead to severe illness and require discontinuation of chemotherapy. When we administer docetaxel over a prolonged period, we should be aware of this adverse effect.
authors.affiliation: Dept. of Medicine, Hitachi General Hospital.
authors.forename: Ryoichi
authors.initials: R
authors.lastname: Namba
authors.forename: Jun
authors.initials: J
authors.lastname: Kanazawa
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Yamamoto
authors.forename: Shusaku
authors.initials: S
authors.lastname: Itou
authors.forename: Takeshi
authors.initials: T
authors.lastname: Nawa
mesh_terms: D000368:Aged; D000970:Antineoplastic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D001706:Biopsy; D003131:Combined Modality Therapy; D000077143:Docetaxel; D004322:Drainage; D006258:Head and Neck Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000532:radiotherapy; D006394:Hemangiosarcoma / Q000188:drug therapy* / Q000473:pathology / Q000532:radiotherapy; D006801:Humans; D008297:Male; D016066:Pleural Effusion, Malignant / Q000139:chemically induced*; D012535:Scalp / Q000473:pathology*; D012878:Skin Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000532:radiotherapy; D043823:Taxoids / Q000009:adverse effects* / Q000627:therapeutic use; D014057:Tomography, X-Ray Computed
chemical_list: D000970:Antineoplastic Agents; D043823:Taxoids; D000077143:Docetaxel