title: Dentist-physician George J. Ziegler: rogue researcher, "cosmic" editor and social activist.
abstract: An industrious self-made man, George Jacob Ziegler (1821-1895) was successively a hairdresser, dentist, physician, author and editor. He is best known as the medical editor of the Periscope section of the Dental Cosmos, and as a social activist who championed the welfare of soldiers, women, and nonsmokers. Ziegler's most unfortunate legacy was his research on dogs, which he misinterpreted as demonstrating nitrous oxide's safety in resuscitation. Pointing to Ziegler's work, dental anesthetist G.Q. Colton would popularize clinical use of 100% nitrous-oxide anesthetics during his 35-year professional career. Consequently, hundreds of thousands of patients worldwide received asphyxial anesthetics.
authors.affiliation: Department of Anesthesiology and Perioperative Medicine, School of Medicine, Case Western Reserve University, USA. UJYC@aol.com
authors.forename: George S
authors.initials: GS
authors.lastname: Bause
mesh_terms: D000776:Anesthesiology / Q000266:history*; D018685:Anesthetics, Inhalation / Q000266:history; D003815:Dentists / Q000266:history*; D049672:History, 19th Century; D006801:Humans; D009609:Nitrous Oxide / Q000266:history; D010414:Pennsylvania
chemical_list: D018685:Anesthetics, Inhalation; D009609:Nitrous Oxide