title: A proportional hazards regression model for the subdistribution with right-censored and left-truncated competing risks data.
abstract: With competing risks failure time data, one often needs to assess the covariate effects on the cumulative incidence probabilities. Fine and Gray proposed a proportional hazards regression model to directly model the subdistribution of a competing risk. They developed the estimating procedure for right-censored competing risks data, based on the inverse probability of censoring weighting. Right-censored and left-truncated competing risks data sometimes occur in biomedical researches. In this paper, we study the proportional hazards regression model for the subdistribution of a competing risk with right-censored and left-truncated data. We adopt a new weighting technique to estimate the parameters in this model. We have derived the large sample properties of the proposed estimators. To illustrate the application of the new method, we analyze the failure time data for children with acute leukemia. In this example, the failure times for children who had bone marrow transplants were left truncated.
authors.affiliation: Department of Mathematics and Statistics, Georgia State University, Atlanta, GA 30303, USA. matxxz@langate.gsu.edu
authors.forename: Xu
authors.initials: X
authors.lastname: Zhang
authors.forename: Mei-Jie
authors.initials: MJ
authors.lastname: Zhang
authors.forename: Jason
authors.initials: J
authors.lastname: Fine
mesh_terms: D056808:Biostatistics / Q000379:methods*; D016026:Bone Marrow Transplantation; D002648:Child; D003627:Data Interpretation, Statistical; D006801:Humans; D007938:Leukemia / Q000628:therapy; D016016:Proportional Hazards Models; D012306:Risk; D013997:Time Factors; D017211:Treatment Failure