title: Clinical impact of blood cultures contaminated with coagulase-negative staphylococci at an academic medical center.
abstract: Of all blood cultures positive for coagulase-negative staphylococci collected in 1 year at an academic hospital, 100 were selected randomly for review and designated true positives or contaminated. For the 85 patients whose cultures were determined to be contaminated, chart abstractions revealed substantial unnecessary antibiotic administration, additional laboratory tests and procedures, and hospital readmissions.
authors.affiliation: Division of Infectious Diseases, Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA. yuri.vanderheijden@vanderbilt.edu
authors.forename: Yuri F
authors.initials: YF
authors.lastname: van der Heijden
authors.forename: Geraldine
authors.initials: G
authors.lastname: Miller
authors.forename: Patty W
authors.initials: PW
authors.lastname: Wright
authors.forename: Bryan E
authors.initials: BE
authors.lastname: Shepherd
authors.forename: Titus L
authors.initials: TL
authors.lastname: Daniels
authors.forename: Thomas R
authors.initials: TR
authors.lastname: Talbot
mesh_terms: D000046:Academic Medical Centers; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D016470:Bacteremia / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D001800:Blood Specimen Collection; D003030:Coagulase / Q000096:biosynthesis; D005189:False Positive Reactions; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013203:Staphylococcal Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D013210:Staphylococcus / Q000201:enzymology / Q000302:isolation & purification; D019564:Unnecessary Procedures
chemical_list: D000900:Anti-Bacterial Agents; D003030:Coagulase