title: Botcinolide/botcinin: asymmetric synthesis of the key fragments.
abstract: The asymmetric synthesis of key fragments of the phytotoxic toxins botcinolide/botcinin is reported. The synthesis of 1 and 1a are based on a convergent route via esterification and alkene metathesis of fragments A, B or C, B, which were obtained by Evans aldol condensation and stereoselective crotylation, respectively.
authors.affiliation: Departamento de Química Orgánica, Facultad de Ciencias, Universidad de Cádiz, Poligono Rio San Pedro s/n, 11510 Puerto Real, Cádiz, Spain.
authors.forename: Jacinto
authors.initials: J
authors.lastname: Ramírez-Fernández
authors.forename: José Manuel
authors.initials: JM
authors.lastname: Botubol
authors.forename: Antonio J
authors.initials: AJ
authors.lastname: Bustillo
authors.forename: Josefina
authors.initials: J
authors.lastname: Aleu
authors.forename: Isidro G
authors.initials: IG
authors.lastname: Collado
authors.forename: Rosario
authors.initials: R
authors.lastname: Hernández-Galán
mesh_terms: D003651:Decanoates / Q000138:chemical synthesis*; D007783:Lactones / Q000138:chemical synthesis*; D011753:Pyrones / Q000138:chemical synthesis*
chemical_list: D003651:Decanoates; D007783:Lactones; D011753:Pyrones; C101236:botcinolide