title: [Recommendations of Neuroendocrinology Department from Brazilian Society of Endocrinology and Metabolism for diagnosis and treatment of acromegaly in Brazil].
abstract: Acromegaly is a disease associated with increased morbidity and reduced life expectancy. Because of its insidious character and its non-recognition, the diagnosis is often made with delay, which, along with the complications related to GH/IGF-I excess, determines high morbidity and mortality. However, an early diagnosis and an effective treatment reduce the morbidity and normalize the mortality rate. In this publication, the goal of Neuroendocrinology Department from Brazilian Society of Endocrinology and Metabolism is to disclose which clinical set should arouse the suspicious of acromegaly and how to diagnose it. Furthermore, we discuss the most effective and safe approach to perform the treatment of acromegaly, emphasizing that it must be carried out in reference centers. Therefore, based on data published in journals with recognized scientific level and authors' experience, recommendations are presented for diagnosis and treatment of the disease.
authors.affiliation: Hospital Universitário Clementino Fraga Filho, Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro, RJ, Brasil.
authors.forename: Leonardo
authors.initials: L
authors.lastname: Vieira Neto
authors.forename: Julio
authors.initials: J
authors.lastname: Abucham
authors.forename: Luiz Antônio de
authors.initials: LA
authors.lastname: Araujo
authors.forename: Cesar L
authors.initials: CL
authors.lastname: Boguszewski
authors.forename: Marcello D
authors.initials: MD
authors.lastname: Bronstein
authors.forename: Mauro
authors.initials: M
authors.lastname: Czepielewski
authors.forename: Raquel S
authors.initials: RS
authors.lastname: Jallad
authors.forename: Nina R de C
authors.initials: NR
authors.lastname: Musolino
authors.forename: Luciana A
authors.initials: LA
authors.lastname: Naves
authors.forename: Antônio
authors.initials: A
authors.lastname: Ribeiro-Oliveira Júnior
authors.forename: Lucio
authors.initials: L
authors.lastname: Vilar
authors.forename: Manuel Dos S
authors.initials: Mdos S
authors.lastname: Faria
authors.forename: Mônica R
authors.initials: MR
authors.lastname: Gadelha
mesh_terms: D000172:Acromegaly / Q000175:diagnosis* / Q000628:therapy*; D001938:Brazil; D019382:Human Growth Hormone / Q000378:metabolism; D006801:Humans; D013577:Syndrome
chemical_list: D019382:Human Growth Hormone