title: 2-(3-Bromo-4-meth-oxy-phen-yl)acetic acid.
abstract: The title compound C(9)H(9)BrO(3), was synthesized by the regioselective bromination of 4-meth-oxy-phenyl-acetic acid using bromine in acetic acid in a 84% yield. In the mol-ecular structure, the meth-oxy group is almost coplanar with the phenyl ring within 0.06 Å; the acetic acid substituent is tilted by 78.15 (7)° relative to the ring. The C-C-C angles at the OMe, acetyl and Br substituents are 118.2 (2), 118.4 (2) and 121.5 (2)°, respectively, indicating that the Br atom is electron-withdrawing, whereas the other substituents possess electron-donating properties. In the crystal, the mol-ecules form centrosymmetric strongly O-H⋯O hydrogen-bonded dimers of the type R(2) (2)(8).
authors.affiliation: Department of Chemistry, University of Wisconsin-Madison, 1101 University Ave, Madison, WI 53706, USA.
authors.forename: Ilia A
authors.initials: IA
authors.lastname: Guzei
authors.forename: Alan R
authors.initials: AR
authors.lastname: Gunderson
authors.forename: Nicholas J
authors.initials: NJ
authors.lastname: Hill