title: Remarkable facilitation of hetero-cycloisomerizations with water and other polar protic solvents: metal-free synthesis of indolizines.
abstract: Hetero-cycloisomerization reactions of propargylic alcohol derivatives leading to indolizines have been demonstrated to proceed in the presence of water alone. This stands as a significant advance over the previous methods using Pt, Cu or Ag salts paired with ligands in organic solvents such as benzene, acetonitrile or methylene chloride.
authors.affiliation: Department of Chemistry, University of California, Berkeley, California, 94720, USA.
authors.forename: Alison R
authors.initials: AR
authors.lastname: Hardin Narayan
authors.forename: Richmond
authors.initials: R
authors.lastname: Sarpong