title: [Acute lymphatic leukaemia with eosinophilia in a younger man returning from a travel in the tropics--case report].
abstract: A 22-year-old man presented with severe back pain and 60% eosinophilia after returning from the tropics. An extensive investigation for parasitic diseases was negative. Over time, his haemoglobin level and thrombocyte count fell, and the spleen and several lymph nodes were enlarged. The patient was diagnosed with acute lymphatic leukaemia with eosinophilia by bone marrow microscopy and flow cytometry. Chromosome analysis detected clonal abnormalities including t(5;14)(q31;q32). He initially responded to chemotherapy, but due to residual disease, he now awaits allogeneic bone marrow transplantation.
authors.affiliation: Infektionsmedicinsk Afdeling, Hvidovre Hospital, 2650 Hvidovre, Denmark. mvlarsen@dadlnet.dk
authors.forename: Mette Vang
authors.initials: MV
authors.lastname: Larsen
authors.forename: Kristian
authors.initials: K
authors.lastname: Karstoft
authors.forename: Mette Klarskov
authors.initials: MK
authors.lastname: Andersen
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D003937:Diagnosis, Differential; D006801:Humans; D017681:Hypereosinophilic Syndrome / Q000175:diagnosis* / Q000188:drug therapy / Q000235:genetics; D008297:Male; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000175:diagnosis* / Q000188:drug therapy / Q000235:genetics; D014195:Travel; D017211:Treatment Failure; D014330:Tropical Medicine; D055815:Young Adult