title: [Cost-benefit analysis in setting up limitation standards of aflatoxins in foods].
abstract: OBJECTIVE
  To explore a reasonable limitation standard for aflatoxins in foods to protect the health of people in China with a cost-benefit analysis.
  
  
  METHODS
  A traditional mathematical model and MOE (margin of exposure) method was used to assess the effect of different limiting standards on health for total aflatoxins and aflatoxin B1 in peanut, corn and rice, and the loss of foods under different limiting standard levels was also calculated.
  
  
  RESULTS
  The change of limiting standards for total aflatoxins and aflatoxin B1 in peanut and corn might have no significant influence on reducing the prevalence of liver cancer in China, but the loss of foods was significantly different. The change of limiting standards for total aflatoxins and aflatoxin B1 in ice might have significant influence both on reducing liver cancer and losing foods.
  
  
  CONCLUSIONS
  The following limiting standards is advisable: 20 microg/kg for total aflatoxins and 15 microg/kg for Aflatoxin B1 in peanut and its products, 20 microg/kg for total aflatoxins and 15 microg/kg for aflatoxin B1 in corn, 10 microg/kg for total aflatoxins and 5 microg/kg or 10 microg/kg for aflatoxin B1 in rice.
authors.affiliation: Institute of Nutrition and Food Safety, Chinese Center for Disease Control and Prevention, Beijing 100021, China. wjwangjun2008@gmail.com
authors.forename: Jun
authors.initials: J
authors.lastname: Wang
authors.forename: Xiumei
authors.initials: X
authors.lastname: Liu
mesh_terms: D000348:Aflatoxins / Q000032:analysis*; D010367:Arachis / Q000737:chemistry; D002681:China; D003362:Cost-Benefit Analysis; D005504:Food Analysis / Q000191:economics / Q000592:standards*; D005506:Food Contamination / Q000032:analysis* / Q000517:prevention & control*; D005516:Food Microbiology / Q000191:economics / Q000592:standards*; D006801:Humans; D003313:Zea mays / Q000737:chemistry
chemical_list: D000348:Aflatoxins