title: Essential oils from wild populations of Algerian Lavandula stoechas L.: composition, chemical variability, and in vitro biological properties.
abstract: In an effort to develop local productions of aromatic and medicinal plants, a comprehensive assessment of the composition and biological activities of the essential oils (EOs) extracted from the aerial flowering parts of wild growing Lavandula stoechas L. collected from eleven different locations in northern Algeria was performed. The oils were characterized by GC-FID and GC/MS analyses, and 121 compounds were identified, accounting for 69.88-91.2% of the total oil compositions. The eleven oils greatly differed in their compositions, since only 66 compounds were common to all oils. Major EO components were fenchone (2; 11.27-37.48%), camphor (3, 1.94-21.8%), 1,8-cineole (1; 0.16-8.71%), and viridiflorol (10; 2.89-7.38%). The assessed in vitro biological properties demonstrated that the DPPH-based radical-scavenging activities and the inhibition of the β-carotene/linoleic acid-based lipid oxidation differed by an eight-fold factor between the most and the least active oils and were linked to different sets of molecules in the different EOs. The eleven EOs exhibited good antimicrobial activities against most of the 16 tested strains of bacteria, filamentous fungi, and yeasts, with minimum inhibitory concentrations (MICs) ranging from 0.16 to 11.90 mg/ml.
authors.affiliation: Département de Biologie, Faculté des Sciences, Université M'hamed Bougara, 35000 Boumerdes, Algeria.
authors.forename: Tarek
authors.initials: T
authors.lastname: Benabdelkader
authors.forename: Abdelghani
authors.initials: A
authors.lastname: Zitouni
authors.forename: Yann
authors.initials: Y
authors.lastname: Guitton
authors.forename: Frédéric
authors.initials: F
authors.lastname: Jullien
authors.forename: Dany
authors.initials: D
authors.lastname: Maitre
authors.forename: Hervé
authors.initials: H
authors.lastname: Casabianca
authors.forename: Laurent
authors.initials: L
authors.lastname: Legendre
authors.forename: Abdelkrim
authors.initials: A
authors.lastname: Kameli
mesh_terms: D000462:Algeria; D000890:Anti-Infective Agents / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects; D001424:Bacterial Infections / Q000188:drug therapy; D035264:Flowers / Q000737:chemistry; D016166:Free Radical Scavengers / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D005658:Fungi / Q000187:drug effects; D008401:Gas Chromatography-Mass Spectrometry; D027523:Lavandula / Q000737:chemistry*; D009181:Mycoses / Q000188:drug therapy; D009822:Oils, Volatile / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D010938:Plant Oils / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D015003:Yeasts / Q000187:drug effects
chemical_list: D000890:Anti-Infective Agents; D016166:Free Radical Scavengers; D009822:Oils, Volatile; D010938:Plant Oils