title: (S)-2-[(2R,3S)-2-Ammonio-3-hydr-oxy-3-(4-nitro-phen-yl)propanamido]-4-methyl-penta-noate monohydrate.
abstract: The structure of the title compound, C(15)H(21)N(3)O(6)·H(2)O, is of inter-est with respect to assumed anti-cancer activity. The title mol-ecules are linked through inter-molecular O-H⋯O hydrogen-bonded chains along the a axis. These chains are connected by inter-molecular N-H⋯O hydrogen bonds through the crystallographic screw axis along [010], forming layers, which are stabilized by other N-H⋯O bonds with water O atoms as acceptors and O-H⋯O bonds with water H atoms as donors. The H atoms of the protonated amino cation are also involved in inter-molecular N-H⋯O bonding inter-actions.
authors.affiliation: Institute of Medicinal Chemistry, School of Pharmacy, Shandong University, Ji'nan 250012, People's Republic of China.
authors.forename: Kang-Hui
authors.initials: KH
authors.lastname: Yang
authors.forename: Xun
authors.initials: X
authors.lastname: Li
authors.forename: Jian-Zhi
authors.initials: JZ
authors.lastname: Gong
authors.forename: Hao
authors.initials: H
authors.lastname: Fang
authors.forename: Wen-Fang
authors.initials: WF
authors.lastname: Xu