title: A turn-on chemosensor for Hg2+ in aqueous media and its application in "MCT" imaging in living cells.
abstract: A turn-on chemosensor L1, which exhibits high selectivity and sensitivity toward Hg(2+) over other common metal ions in aqueous media under a physiological pH window via a 1:1 binding mode, had been synthesized and characterized. L1 provides good fluorescent imaging of Hg(2+) in living cells. Particularly, we adopted the "micro computed tomography (MCT)" technology, successfully demonstrating the method of Hg(2+) sensing by L1 in cell lines, also the cell permeability of L1 and its imaging position in the cells.
authors.affiliation: Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu Province, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, PR China.
authors.forename: Pinxian
authors.initials: P
authors.lastname: Xi
authors.forename: Liang
authors.initials: L
authors.lastname: Huang
authors.forename: Guoqiang
authors.initials: G
authors.lastname: Xie
authors.forename: Fengjuan
authors.initials: F
authors.lastname: Chen
authors.forename: Zhihong
authors.initials: Z
authors.lastname: Xu
authors.forename: Decheng
authors.initials: D
authors.lastname: Bai
authors.forename: Zhengzhi
authors.initials: Z
authors.lastname: Zeng
mesh_terms: D045744:Cell Line, Tumor; D018360:Crystallography, X-Ray; D005456:Fluorescent Dyes / Q000737:chemistry; D006801:Humans; D008628:Mercury / Q000032:analysis*; D008968:Molecular Conformation; D012235:Rhodamines / Q000737:chemistry*; D013050:Spectrometry, Fluorescence; D014867:Water / Q000737:chemistry*
chemical_list: D005456:Fluorescent Dyes; D012235:Rhodamines; D014867:Water; D008628:Mercury