title: Review of use of drugs for conditions not included in product characteristics.
abstract: Off-label use of medication is common in hospital clinical practice and should be applied together with follow-up of a healthcare treatment protocol and in compliance with a procedure which ensures that the patient is informed and that he or she provides informed consent. A review of the literature on controlling 310 disorders showed that off-label use was indicated for 69 of them (22.3%) with the minimum required scientific evidence. It would be useful for the Pharmacy and Therapeutics Committee to have a list of the disorders that can be controlled using off-label drugs, providing a reference to those disorders which must follow a healthcare treatment protocol. A list of the mentioned characteristics is also useful for the hospital pharmacist for validating prescriptions, as it would provide a reference for assessing prescriptions which at first sight could seem questionable. Finally, this list would be very useful if a search index of all the drugs by disorder were to be included in the Pharmacotherapeutic Guide. It would complement the usual indices which include active ingredients and specialties.
authors.affiliation: Servicio de Farmacia, Hospital Lucus Augusti, Lugo, Spain. antonio.garcia.sabina@sergas.es
authors.forename: A
authors.initials: A
authors.lastname: García-Sabina
authors.forename: R
authors.initials: R
authors.lastname: Rabuñal Rey
authors.forename: R
authors.initials: R
authors.lastname: Martínez-Pacheco
mesh_terms: D006801:Humans; D056687:Off-Label Use / Q000706:statistics & numerical data*