title: Salvage irradiation of oral and oropharyngeal cancers using interstitial radiotherapy with au-198 grains.
abstract: Fourteen patients with recurrent or persistent carcinoma of the oral cavity or oropharynx were treated with Au-198 grain implants at the Santa Creu i Sant Pau Hospital from June 1987 through April 1991. Five patients presented recurrent carcinoma, four patients persistent carcinoma, and five patients a second primary. Local control was achieved with Au-198 implants in six patients (42.8%) at 8, 16, 23, 29, 39 and 53 months following treatment. Seven patients died of local recurrence or persistent disease at 5, 7, 7, 10, 10, 12 and 15 months after interstitial implant. Three patients (21.4%) died of significant complications of salvage irradiation (Hemorrhage in two patients and edema in one patient) at 0.5, 8 and 16 months following treatment. Three patients of fourteen (21.4%) are alive and well at 53, 39 and 23 months after salvage Au-198 grain implant. Considerations regarding the usefulness of Au-198 grain implants in the treatment of recurrent or persistent oral and oropharyngeal cancer are discussed.
authors.affiliation: HOSP CLIN SANTIAGO DE COMPOSTELA,DEPT RADIAT ONCOL,SANTIAGO,SPAIN.
authors.forename: F
authors.initials: F
authors.lastname: Guedea
authors.forename: L
authors.initials: L
authors.lastname: Cascallar
authors.forename: J
authors.initials: J
authors.lastname: Cravenbartle
authors.forename: T
authors.initials: T
authors.lastname: Eudaldo
authors.forename: M
authors.initials: M
authors.lastname: Vega