title: Potential applications of silk sericin, a natural protein from textile industry by-products.
abstract: Silk is composed of two major proteins, fibroin (fibrous protein) and sericin (globular, gumming protein). Fibroin has been used in textile manufacturing and for several biomaterial applications, whereas sericin is considered a waste material in the textile industry. Sericin has recently been found to activate the proliferation of several cell-lines and has also shown various biological activities. Sericin can form a gel by itself; however, after mixing with other polymers and cross-linking it can form a film or a scaffold with good characteristics that can be used in the cosmetic and pharmaceutical industries. Sericin is proven to cause no immunological responses, which has resulted in a more acceptable material for biological applications.
authors.affiliation: Department of Pharmacy Practice, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand. aramwit@gmail.com
authors.forename: Pornanong
authors.initials: P
authors.lastname: Aramwit
authors.forename: Tippawan
authors.initials: T
authors.lastname: Siritientong
authors.forename: Teerapol
authors.initials: T
authors.lastname: Srichana
mesh_terms: D000818:Animals; D001672:Biocompatible Materials / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology / Q000627:therapeutic use*; D012831:Bombyx / Q000737:chemistry* / Q000502:physiology; D005349:Fibroins / Q000737:chemistry / Q000302:isolation & purification; D019476:Insect Proteins / Q000737:chemistry / Q000494:pharmacology / Q000502:physiology / Q000627:therapeutic use*; D047030:Sericins / Q000737:chemistry / Q000494:pharmacology / Q000502:physiology / Q000627:therapeutic use*; D013783:Textile Industry; D014866:Waste Products
chemical_list: D001672:Biocompatible Materials; D019476:Insect Proteins; D047030:Sericins; D014866:Waste Products; D005349:Fibroins