title: Comparison of 2 vitamin D supplementation modalities in newborns: adherence and preference.
abstract: Lack of adherence with vitamin D supplementation is still a risk factor for rickets. In a randomized cross-over design, infants received 400 IU cholecalciferol by dropper (1 mL syrup) or filmstrip. Infant and parent preference scores and adherence were then compared. Forty-three parents of healthy infants preferred the filmstrip (85.4% of parents; 95% confidence interval of 70.1%-93.9%; p < 0.001), a result that was corroborated by higher infant and parental scores and compliance. Ease of administration of supplements with improved acceptance may improve adherence.
authors.affiliation: Montreal Children's Hospital, McGill University, Montreal, Canada. celia.rodd@mcgill.ca
authors.forename: Celia
authors.initials: C
authors.lastname: Rodd
authors.forename: Sonia
authors.initials: S
authors.lastname: Jean-Philippe
authors.forename: Catherine
authors.initials: C
authors.lastname: Vanstone
authors.forename: Hope
authors.initials: H
authors.lastname: Weiler
mesh_terms: D000284:Administration, Oral; D002762:Cholecalciferol / Q000008:administration & dosage* / Q000494:pharmacology*; D018592:Cross-Over Studies; D019587:Dietary Supplements; D004304:Dosage Forms; D006801:Humans; D007231:Infant, Newborn; D010349:Patient Compliance; D014808:Vitamin D Deficiency / Q000517:prevention & control
chemical_list: D004304:Dosage Forms; D002762:Cholecalciferol