title: 2,4-Bis(2-fluoro-phen-yl)-1-methyl-3-aza-bicyclo-[3.3.1]nonan-9-one.
abstract: The crystal structure of the title compound, C(21)H(21)F(2)NO, shows that the compound exists in a twin-chair conformation with an equatorial orientation of the ortho-fluoro-phenyl groups on either side of the secondary amino group. The title compound is a 1-methyl-ated analog of 2,4-bis-(2-fluoro-phen-yl)-3-aza-bicyclo-[3.3.1]nonan-9-one; the two compound both exhibit the same stereochemistry but the orientation of the ortho-fluoro-phenyl rings differs slightly. In the title compound, the rings are orientated at a dihedral angle of 36.70 (3)° with respect to one another, whereas in the non-methyl analog, the angle is 25.68 (4)°. The crystal structure of the title compound is stabilized by an inter-molecular N-H⋯π inter-action and a weak C-H⋯F inter-action.
authors.forename: P
authors.initials: P
authors.lastname: Parthiban
authors.forename: V
authors.initials: V
authors.lastname: Ramkumar
authors.forename: Yeon Tae
authors.initials: YT
authors.lastname: Jeong