title: Genetic stability of microsatellites in human neuroblastomas.
abstract: Genetic instability resulting from deficiency in replication error repair (RER) has been detected in a variety of human cancers. We have examined the stability of five 1p microsatellites in 51 human neuroblastomas including stages 1, 2, 3, 4 and 4s. None of the tumors showed an aberrant pattern indicating RER at any microsatellite. Our results do not support a major role for increased genetic instability as the result of deficient replication error repair in neuroblastoma.
authors.affiliation: GERMAN CANC RES CTR,DEPT CYTOGENET 0130,D-69120 HEIDELBERG,GERMANY. UNIV COLOGNE,CHILDRENS HOSP,D-50931 COLOGNE,GERMANY.
authors.forename: M
authors.initials: M
authors.lastname: Gehring
authors.forename: F
authors.initials: F
authors.lastname: Berthold
authors.forename: M
authors.initials: M
authors.lastname: Schwab
authors.forename: L
authors.initials: L
authors.lastname: Amler