title: From efficacy to effectiveness in the face of uncertainty: indication creep and prevention creep.
authors.affiliation: Center for Evidence-based Medicine and Health Outcomes Research, University of South Florida, 12901 Bruce B. Downs Blvd, MDC27, Room 3127/3126, Tampa, FL 33612, USA. bdjulbeg@health.usf.edu
authors.forename: Benjamin
authors.initials: B
authors.lastname: Djulbegovic
authors.forename: Ash
authors.initials: A
authors.lastname: Paul
mesh_terms: D035843:Biomedical Research; D002986:Clinical Trials as Topic; D057186:Comparative Effectiveness Research; D003657:Decision Making; D004992:Ethics, Medical; D005188:False Negative Reactions; D005189:False Positive Reactions; D006295:Health Resources / Q000706:statistics & numerical data; D054625:Healthcare Disparities; D006801:Humans; D040841:Resource Allocation; D012945:Social Values; D016896:Treatment Outcome; D035501:Uncertainty