title: [Study on the distribution of HPV subtypes in Uighur people living in the Karsay township, Moyu county, Xinjiang].
abstract: OBJECTIVE
  To study the distribution of human papilloma virus (HPV) subtypes in Uyghur people from the high risk region of cervical cancer in Xinjiang.
  
  
  METHODS
  21 subtypes of HPV from 400 cases of men's swabs of penile and 400 cases of women's cervix swabs were detected, using flow-through hybridization and gene chip technology.
  
  
  RESULTS
  (1) The positive rate of HPV among the 400 women cases was 14.25%, with HPV16 the most common type. In women whose HPV was positive, the positive rate of HPV16 was 66.67%. The ranking of frequencies on the HPV subtypes in women were:HPV16, 58, 39, 18, 33, 52, 43, 66, CP8304, HPV6 and 11. (2) Among the 400 male cases, the positive rate of HPV was 8.00%, with HPV16 the most common type. In men whose HPV was positive, the rate of HPV16 was 44.44%. The ranking of HPV subtypes in men were HPV16, 43, 33, 39, 6 (HPV39 and 6 are equivalent) and 53. (3) Both wives and husbands were infected by different subtypes of HPV, the positive rate was relatively low among men whose wife's HPV were positive. However, the HPV positive rate was relatively low among women whose husband's HPV were positive. The concordance infection rate of women and men were 7.02% and the concordance infection rate of men and women were 9.38%.
  
  
  CONCLUSIONS
  The HPV positive rates were relatively low in both men and women living in the region with high risk of cervical cancer in Xinjiang. However, the positive rate of high risk types HPV and HPV16 in both men and women were relatively high. Uyghur men seemed to have played a certain role related to the carcinogenesis of cervical cancer. HPV16 was the main type in both men and women in Xinjiang.
authors.affiliation: The Fifth Department of Gynecology of the Affiliated Tumor Hospital Xinjiang University, Urumqi 830011, China.
authors.forename: Tangnur
authors.initials: T
authors.lastname: Ablimit
authors.forename: Muyassaer
authors.initials: M
authors.lastname: Turgan
authors.forename: Guzalnur
authors.initials: G
authors.lastname: Abliz
authors.forename: Aynur
authors.initials: A
authors.lastname: Mamat
authors.forename: Gulnar
authors.initials: G
authors.lastname: Kurban
authors.forename: Su-Qin
authors.initials: SQ
authors.lastname: Zhang
authors.forename: Hamrahul
authors.initials: H
authors.lastname: Abaydulla
authors.forename: Ibadat
authors.initials: I
authors.lastname: Abdukadir
authors.forename: Kunduz
authors.initials: K
authors.lastname: Abdulla
mesh_terms: D000328:Adult; D000368:Aged; D002584:Cervix Uteri / Q000821:virology; D002681:China / Q000453:epidemiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D027383:Papillomaviridae / Q000145:classification* / Q000302:isolation & purification; D030361:Papillomavirus Infections / Q000208:ethnology; D011795:Surveys and Questionnaires; D002583:Uterine Cervical Neoplasms / Q000208:ethnology / Q000821:virology*; D055815:Young Adult; D002578:Uterine Cervical Dysplasia / Q000208:ethnology / Q000821:virology*