title: Epidermal growth-factor receptor expression in malignant ovary, benign ovarian-tumors and normal ovary - a comparison.
abstract: Epidermal growth factor receptor (EGFR) was assayed and compared in malignant ovaries, benign ovarian tumours and normal ovaries. The EGFR was present in 39.7% of malignant ovaries, 13.3% of benign ovarian tumours and in 15.4% of normal ovaries. In the malignant group 36 samples had a low affinity component, 27 had a high affinity component and 16 had both high and low affinity components. The benign ovarian group had 1 high affinity and 3 low affinity components while the normal ovaries had 3 high affinity and 5 low affinity components. The sensitivity of the EGFR assay was 39.7% and the specificity 85.4%.
authors.affiliation: UNIV GLASGOW,DEPT BIOCHEM,GLASGOW G12 8QQ,SCOTLAND.
authors.forename: O
authors.initials: O
authors.lastname: Owens
authors.forename: R
authors.initials: R
authors.lastname: Leake