title: [Modern approach to the prevention and treatment of NSAID-gastropathy].
abstract: The article presents the results of the first Russian open randomized comparative multicenter study on the effectiveness of Famotidine in the prevention of NSAID-gastropathy--Barrier. In addition, were showen the results of studies of the drugs effect used for prevention of NSAID gastropathy (Famotidine, Lansoprazole, Misoprostol) for the synthesis of prostaglandins in the gastric mucosa in patients with osteoarthritis. Was shown the impact of alternative anti-inflammatory drug on the basis of an extract of ginger as joint pain, and the mucous upper gastrointestinal tract in patients with osteoarthritis.
authors.forename: V N
authors.initials: VN
authors.lastname: Drozdov
authors.forename: V A
authors.initials: VA
authors.lastname: Kim
authors.forename: L B
authors.initials: LB
authors.lastname: Lazebnik
mesh_terms: D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D000897:Anti-Ulcer Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D004008:Diclofenac / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D015738:Famotidine / Q000008:administration & dosage / Q000627:therapeutic use*; D005753:Gastric Mucosa / Q000187:drug effects / Q000378:metabolism / Q000473:pathology; D005755:Gastrins / Q000097:blood; D006801:Humans; D008875:Middle Aged; D010437:Peptic Ulcer / Q000139:chemically induced / Q000378:metabolism / Q000517:prevention & control*; D011453:Prostaglandins / Q000096:biosynthesis; D016896:Treatment Outcome
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D000897:Anti-Ulcer Agents; D005755:Gastrins; D011453:Prostaglandins; D004008:Diclofenac; D015738:Famotidine; C013550:gastrin 17