title: Familial Brugada syndrome uncovered by hyperkalaemic diabetic ketoacidosis.
abstract: We describe a case of diabetic ketoacidosis with concomitant hyperkalaemia that uncovered a typical Brugada syndrome electrocardiogram (ECG). Further provocation testing in the patient and his son confirmed familial Brugada syndrome. Diabetic ketoacidosis with hyperkalaemia may uncover an inheritable arrhythmia syndrome that may put the patient and his/her next of kin at risk for a sudden death, irrespective of diabetes mellitus.
authors.affiliation: Department of Cardiology, Academic Medical Center, Meibergdreef 9, 1105AZ Amsterdam, The Netherlands. p.g.postema@amc.uva.nl
authors.forename: Pieter G
authors.initials: PG
authors.lastname: Postema
authors.forename: Alexander P J
authors.initials: AP
authors.lastname: Vlaar
authors.forename: J Hans
authors.initials: JH
authors.lastname: DeVries
authors.forename: Hanno L
authors.initials: HL
authors.lastname: Tan
mesh_terms: D001064:Appendicitis / Q000150:complications / Q000601:surgery; D053840:Brugada Syndrome / Q000175:diagnosis / Q000235:genetics* / Q000503:physiopathology; D015897:Comorbidity; D016883:Diabetic Ketoacidosis / Q000150:complications* / Q000453:epidemiology / Q000209:etiology; D004562:Electrocardiography; D006801:Humans; D006947:Hyperkalemia / Q000150:complications* / Q000453:epidemiology / Q000209:etiology; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome