title: Risk factors for urinary tract infection following incontinence surgery.
abstract: OBJECTIVE
  The purpose of this study is to describe risk factors for post-operative urinary tract infection (UTI) the first year after stress urinary incontinence surgery.
  
  
  METHODS
  Multivariable logistic regression analyses were performed on data from 1,252 women randomized in two surgical trials, Stress Incontinence Surgical Treatment Efficacy trial (SISTEr) and Trial Of Mid-Urethral Slings (TOMUS).
  
  
  RESULTS
  Baseline recurrent UTI (rUTI; ≥3 in 12 months) increased the risk of UTI in the first 6 weeks in both study populations, as did sling procedure and self-catheterization in SISTEr, and bladder perforation in TOMUS. Baseline rUTI, UTI in the first 6 weeks, and PVR > 100 cc at 12 months were independent risk factors for UTI between 6 weeks and 12 months in the SISTEr population. Few (2.3-2.4%) had post-operative rUTI, precluding multivariable analysis. In women with pre-operative rUTI, successful surgery (negative cough stress test) at 1 year did not appear to decrease the risk of persistent rUTI.
  
  
  CONCLUSIONS
  Pre-operative rUTI is the strongest risk factor for post-operative UTI.
authors.affiliation: Department of OB/GYN, University Utah, Salt Lake City, UT, USA. Ingrid.nygaard@hsc.utah.edu
authors.forename: Ingrid
authors.initials: I
authors.lastname: Nygaard
authors.forename: Linda
authors.initials: L
authors.lastname: Brubaker
authors.forename: Toby C
authors.initials: TC
authors.lastname: Chai
authors.forename: Alayne D
authors.initials: AD
authors.lastname: Markland
authors.forename: Shawn A
authors.initials: SA
authors.lastname: Menefee
authors.forename: Larry
authors.initials: L
authors.lastname: Sirls
authors.forename: Gary
authors.initials: G
authors.lastname: Sutkin
authors.forename: Phillipe
authors.initials: P
authors.lastname: Zimmern
authors.forename: Amy
authors.initials: A
authors.lastname: Arisco
authors.forename: Liyuan
authors.initials: L
authors.lastname: Huang
authors.forename: Sharon
authors.initials: S
authors.lastname: Tennstedt
authors.forename: Anne
authors.initials: A
authors.lastname: Stoddard
mesh_terms: D000328:Adult; D005260:Female; D013509:Gynecologic Surgical Procedures; D006801:Humans; D016015:Logistic Models; D008875:Middle Aged; D011184:Postoperative Period; D057234:Preoperative Period; D012189:Retrospective Studies; D012307:Risk Factors; D053825:Suburethral Slings; D014550:Urinary Incontinence, Stress / Q000601:surgery*; D014552:Urinary Tract Infections / Q000453:epidemiology*