title: Prevalence of metallo-β-lactamase producing Pseudomonas aeruginosa and Acinetobacter species in intensive care areas in a tertiary care hospital.
abstract: A total of 39 non-duplicate isolates of carbapenem-resistant Pseudomonas aeruginosa and Acinetobacter species isolated from blood and endotracheal secretions were tested for metallo-β-lactamase (MBL) production by modified-EDTA disc synergy and double disc synergy tests. The prevalence of MBLs was 33.33% by both the above tests. All patients with MBL-positive isolates were multidrug resistant and had multiple risk factors like > 8 days hospital stay, catheterization, IV lines, previous antibiotic use, etc. These were risk factors for imipenem resistance also. The overall mortality in MBL-positive patients was 46.15%.
authors.affiliation: Department of Microbiology, L.T.M. Medical College, Mumbai, India.
authors.forename: Anuradha S
authors.initials: AS
authors.lastname: De
authors.forename: Simit H
authors.initials: SH
authors.lastname: Kumar
authors.forename: Sujata M
authors.initials: SM
authors.lastname: Baveja