title: Novel transposable elements from Anopheles gambiae.
abstract: BACKGROUND
  Transposable elements (TEs) are DNA sequences, present in the genome of most eukaryotic organisms that hold the key characteristic of being able to mobilize and increase their copy number within chromosomes. These elements are important for eukaryotic genome structure and evolution and lately have been considered as potential drivers for introducing transgenes into pathogen-transmitting insects as a means to control vector-borne diseases. The aim of this work was to catalog the diversity and abundance of TEs within the Anopheles gambiae genome using the PILER tool and to consolidate a database in the form of a hyperlinked spreadsheet containing detailed and readily available information about the TEs present in the genome of An. gambiae.
  
  
  RESULTS
  Here we present the spreadsheet named AnoTExcel that constitutes a database with detailed information on most of the repetitive elements present in the genome of the mosquito. Despite previous work on this topic, our approach permitted the identification and characterization both of previously described and novel TEs that are further described in detailed.
  
  
  CONCLUSIONS
  Identification and characterization of TEs in a given genome is important as a way to understand the diversity and evolution of the whole set of TEs present in a given species. This work contributes to a better understanding of the landscape of TEs present in the mosquito genome. It also presents a novel platform for the identification, analysis, and characterization of TEs on sequenced genomes.
authors: Fundação Oswaldo Cruz, Escola Nacional de Saúde Pública Sergio Arouca, Av, Brasil, 4365, 21040 360, Rio de Janeiro, Brazil. dfernandezmedina@gmail.com
authors: Rita D
authors: RD
authors: Fernández-Medina
authors: Cláudio J
authors: CJ
authors: Struchiner
authors: José M C
authors: JM
authors: Ribeiro
references: Mol Biol Evol. 2003 Feb;20(2):163-7
references: 12598681
references: Mol Biol Evol. 2003 Nov;20(11):1811-25
references: 12832632
references: Science. 2002 Oct 4;298(5591):129-49
references: 12364791
references: Proc Natl Acad Sci U S A. 2001 Feb 13;98(4):1699-704
references: 11172014
references: Cytogenet Genome Res. 2005;110(1-4):426-40
references: 16093695
references: J Mol Biol. 2005 Aug 5;351(1):108-16
references: 15946679
references: Science. 1996 Nov 1;274(5288):765-8
references: 8864112
references: Mol Biol Evol. 2000 Apr;17(4):540-52
references: 10742046
references: Insect Mol Biol. 2005 Oct;14(5):537-46
references: 16164609
references: Gene. 1988 Dec 15;73(1):237-44
references: 3243435
references: Bioinformatics. 2003 Feb 12;19(3):362-7
references: 12584121
references: Nature. 1985 Jun 27-Jul 3;315(6022):773-6
references: 2409449
references: FEMS Microbiol Lett. 1999 May 15;174(2):247-50
references: 10339815
references: Mol Biol Evol. 2005 Jan;22(1):29-39
references: 15356275
references: Nucleic Acids Res. 2008 Apr;36(7):2284-94
references: 18287116
references: Brief Bioinform. 2007 Nov;8(6):382-92
references: 17932080
references: Evolution. 2009 Dec;63(12):3136-46
references: 19656180
references: Genetics. 2005 Feb;169(2):697-708
references: 15545643
references: Annu Rev Genomics Hum Genet. 2007;8:241-59
references: 17506661
references: Genetics. 2004 Feb;166(2):971-86
references: 15020481
references: J Mol Evol. 2003;57 Suppl 1:S50-9
references: 15008403
references: Mol Biol Evol. 2000 May;17(5):730-7
references: 10779533
references: Bioinformatics. 2005 Jun;21 Suppl 1:i152-8
references: 15961452
references: Proc Natl Acad Sci U S A. 2006 Nov 21;103(47):17600-1
references: 17101965
references: Proc Natl Acad Sci U S A. 1997 Jul 8;94(14):7475-80
references: 9207116
references: Proc Natl Acad Sci U S A. 1996 Aug 6;93(16):8524-9
references: 8710903
references: Proc Natl Acad Sci U S A. 1994 Feb 15;91(4):1411-5
references: 8108422
references: Nat Genet. 2000 May;25(1):25-9
references: 10802651
references: Brief Bioinform. 2004 Jun;5(2):150-63
references: 15260895
references: BMC Genomics. 2006 Mar 24;7:62
references: 16563168
references: Insect Biochem Mol Biol. 2003 Apr;33(4):381-7
references: 12650686
references: Nucleic Acids Res. 2009 Jan;37(Database issue):D205-10
references: 18984618
references: Nucleic Acids Res. 2008 Jul 1;36(Web Server issue):W465-9
references: 18424797
references: Genetica. 2006 Sep-Nov;128(1-3):205-16
references: 17028951
references: Gene. 2001 Jan 24;263(1-2):247-53
references: 11223264
references: Mol Biol Evol. 1996 Mar;13(3):494-504
references: 8742638
references: Cytogenet Genome Res. 2005;110(1-4):457-61
references: 16093698
references: Genome Res. 2000 Jul;10(7):908-15
references: 10899140
references: Genome Res. 1999 Oct;9(10):924-35
references: 10523521
references: Trends Genet. 2000 Sep;16(9):418-20
references: 10973072
references: BMC Bioinformatics. 2006 Oct 10;7:439
references: 17032440
references: Syst Biol. 2003 Oct;52(5):696-704
references: 14530136
references: BMC Genomics. 2006 Aug 18;7:214
references: 16919158
references: Nucleic Acids Res. 2006 Jan 1;34(Database issue):D247-51
references: 16381856
references: Nucleic Acids Res. 1991 Apr 25;19(8):1871-7
references: 1674369
references: Annu Rev Genet. 2007;41:331-68
references: 18076328
references: Mol Biol Evol. 1999 Jun;16(6):793-805
references: 10368957
references: Trends Genet. 1989 Apr;5(4):103-7
references: 2543105
references: Plant Cell. 1992 Oct;4(10):1283-94
references: 1332797
references: Mol Biol Evol. 2003 Apr;20(4):528-40
references: 12654934
references: Science. 2009 Sep 11;325(5946):1352-3
references: 19745141
references: Nature. 2001 Feb 15;409(6822):860-921
references: 11237011
references: Genomics. 2008 May;91(5):467-75
references: 18343092
references: Mol Biol Evol. 2002 Feb;19(2):149-62
references: 11801743
references: Genome. 2005 Oct;48(5):831-9
references: 16391689
references: Genome Res. 2002 Jul;12(7):1075-9
references: 12097344
references: Annu Rev Genet. 1971;5:237-56
references: 16097657
references: Gene. 2007 Mar 1;389(1):1-9
references: 17137733
references: Gene. 2004 Apr 14;330:123-31
references: 15087131
references: Syst Biol. 2006 Aug;55(4):539-52
references: 16785212
references: Nat Rev Genet. 2007 Dec;8(12):973-82
references: 17984973
references: Nucleic Acids Res. 2004 Mar 19;32(5):1792-7
references: 15034147
references: Nature. 1980 Apr 17;284(5757):601-3
references: 6245369
references: BMC Bioinformatics. 2004 Jul 13;5:94
references: 15251040
references: Nat Rev Genet. 2000 Nov;1(2):145-9
references: 11253654
references: Genetica. 2002 May;115(1):49-63
references: 12188048