title: Pentacyclic triterpenes from the resin of Liquidambar formosana.
abstract: Two new pentacyclic triterpenes and eight known pentacyclic triterpenes were isolated from the petroleum ether extract of Liquidambaris Resina. The structural elucidation of these compounds was determined by spectroscopic data interpretation. Their cytotoxic and antiplatelet aggregation activities were examined to find potent cytotoxic and antiplatelet aggregation compounds from natural resources. The results showed that 3-keto oleane triterpenes had strong cytotoxicity against MDA-MB-435S cancer cells and that 28-carboxyl oleane triterpenes possessed significant inhibition of platelet aggregation induced by ADP.
authors: Jiangsu Key Laboratory for TCM Formulae Research, Nanjing University of Traditional Chinese Medicine, Nanjing 210046, China.
authors: Nian-Yun
authors: NY
authors: Yang
authors: Jian-Hua
authors: JH
authors: Chen
authors: Gui-Sheng
authors: GS
authors: Zhou
authors: Yu-Ping
authors: YP
authors: Tang
authors: Jin-Ao
authors: JA
authors: Duan
authors: Li-Juan
authors: LJ
authors: Tian
authors: Xun-Hong
authors: XH
authors: Liu