title: Multidetector row computed tomography of acute pancreatitis: Utility of single portal phase CT scan in short-term follow up.
abstract: OBJECTIVE
  The purpose of this study is to evaluate the question of whether nonenhanced CT or contrast enhanced portal phase CT can replace multiphasic pancreas protocol CT in short term monitoring in patients with acute pancreatitis.
  
  
  METHODS
  This retrospective study was approved by the Institutional Review Board. From April 2006 to May 2010, a total of 52 patients having acute pancreatitis who underwent initial dual phase multidetector row CT (unenhanced, arterial, and portal phase) at admission and a short term (within 30 days) follow up dual phase CT (mean interval 10.3 days, range 3-28 days) were included. Two abdominal radiologists performed an independent review of three sets of follow up CT images (nonenhanced scan, single portal phase scan, and dual phase scan). Interpretation of each image set was done with at least 2-week interval. Radiologists evaluated severity of acute pancreatitis with regard to pancreatic inflammation, pancreatic necrosis, and extrapancreatic complication, based on the modified CT severity index. Scores of each image set were compared using a paired t-test and interobserver agreement was evaluated using intraclass correlation coefficient statistics.
  
  
  RESULTS
  Mean scores of sum of CT severity index on nonenhanced scan, portal phase scan, and dual phase scan were 5.7, 6.6, and 6.5 for radiologist 1, and 5.0, 5.6, and 5.8 for radiologist 2, respectively. In both radiologists, contrast enhanced scan (portal phase scan and dual phase scan) showed significantly higher severity score compared with that of unenhanced scan (P<0.05), while portal phase and dual phase scan showed no significant difference each other. The trend was similar regarding pancreatic inflammation and extrapancreatic complications, in which contrast enhanced scans showed significantly higher score compared with those of unenhanced scan, while no significant difference was observed between portal phase scan and dual phase scan. In pancreatic necrosis analysis, there was no significant difference between the three image sets for both radiologists. However, when only the patients having pancreatic necrosis (n=13) was separately analyzed, significant differences were observed between the unenhanced and portal phase scan (P=0.04, for radiologist 1), or unenhanced and dual phase scan (P=0.013, for radiologist 2).
  
  
  CONCLUSIONS
  For short-term follow up imaging in assessment of patients with acute pancreatitis, single portal phase CT images without adding unenhanced or arterial phase images provide sufficient information, and thereby reduce radiation exposure.
authors: Department of Radiology, Konkuk University Medical Center, 4-12, Hwayang-dong, Gwangjin-gu, Seoul 143-729, Republic of Korea.
authors: Yongwonn
authors: Y
authors: Kwon
authors: Hee Sun
authors: HS
authors: Park
authors: Young Jun
authors: YJ
authors: Kim
authors: Sung Il
authors: SI
authors: Jung
authors: Hae Jeong
authors: HJ
authors: Jeon