title: Inherently chiral phosphonatocavitands as artificial chemo- and enantio-selective receptors of natural ammoniums.
abstract: Inherently chiral phosphonatocavitands with various bridging moieties at their wide rim were synthesized. Optical resolution by chiral HPLC was performed with cavitand 8 to afford enantiopure compounds (+)-8 and (-)-8. The molecular structures of hosts 8 and 12 were determined by X-ray diffraction. The host properties were investigated by (1)H and (31)P NMR spectroscopy. The phosphonatocavitands form inclusion complexes with chiral ammonium neurotransmitters, some presenting enantioselectivity towards the right or left-handed host enantiomers.
authors: Laboratoire de Chimie, CNRS, École Normale Supérieure de Lyon, 46 Allée d'Italie, F-69364 Lyon, France.
authors: Jérôme
authors: J
authors: Vachon
authors: Steven
authors: S
authors: Harthong
authors: Erwann
authors: E
authors: Jeanneau
authors: Christophe
authors: C
authors: Aronica
authors: Nicolas
authors: N
authors: Vanthuyne
authors: Christian
authors: C
authors: Roussel
authors: Jean-Pierre
authors: JP
authors: Dutasta