title: Low toxicity of inhaled interferon-gamma in four patients with lung metastasis from renal cell carcinoma.
abstract: Inhalation of interferon-gamma (IFN-gamma) was used in four patients with pulmonary metastasis from renal cell carcinoma. Three million JRU IFN-gamma were inhaled every day (3 patients) or 5 times per week (1 patient). One patient achieved no change after IFN-gamma inhalation and three patients had no response. No drug-related side effects were observed. These findings point to the clinical feasibility of inhalation of IFN-gamma. However, further studies are needed to establish the anti-tumor efficacy of IFN-gamma inhalation therapy.
authors: UNIV CALIF LOS ANGELES,SCH MED,DEPT MICROBIOL & IMMUNOL,LOS ANGELES,CA 90024.
authors: Y
authors: Y
authors: Mizutani
authors: T
authors: T
authors: Terachi
authors: Y
authors: Y
authors: Kakehi
authors: Y
authors: Y
authors: Okada
authors: O
authors: O
authors: Yoshida
authors: B
authors: B
authors: Bonavida