title: The role of mitochondria in neurodegenerative diseases.
abstract: Mitochondria are implicated in several metabolic pathways including cell respiratory processes, apoptosis, and free radical production. Mitochondrial abnormalities have been documented in neurodegenerative diseases, including Alzheimer's, Parkinson's, and Huntington's diseases, and amyotrophic lateral sclerosis. Several studies have demonstrated that mitochondrial impairment plays an important role in the pathogenesis of this group of disorders. In this review, we discuss the role of mitochondria in the main neurodegenerative diseases and review the updated knowledge in this field.
authors: Clinical Neurology, Section for Neuromuscular Diseases and Neuropathies, University Hospital Spedali Civili, Pz.le Spedali Civili 1, 25100, Brescia, Italy. filosto@med.unibs.it
authors: Massimiliano
authors: M
authors: Filosto
authors: Mauro
authors: M
authors: Scarpelli
authors: Maria Sofia
authors: MS
authors: Cotelli
authors: Valentina
authors: V
authors: Vielmi
authors: Alice
authors: A
authors: Todeschini
authors: Valeria
authors: V
authors: Gregorelli
authors: Paola
authors: P
authors: Tonin
authors: Giuliano
authors: G
authors: Tomelleri
authors: Alessandro
authors: A
authors: Padovani
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