title: [Kawasaki disease in older children and young adults: 10 years of experience in Marseille, France].
abstract: Kawasaki disease is a well-known disease in young children. However, it can also affect older children. The aim of this study was to determine the different characteristics of Kawasaki disease in older children and young adults. This is a descriptive, retrospective, and multicenter study including all cases of Kawasaki disease occurring in children over 8 years and adults hospitalized at children's or adult Hospitals, in Marseille, France, between 1999 and 2009. The clinical, biological, prognostic, and therapeutic data were reviewed for each case. Over a 10-year period, 98 patients were hospitalized for Kawasaki disease. Six cases were aged between 8 years and 1 month and 21 years and 7 months. All patients showed a classic form of the disease with associated organ damage in 5 patients. A cardiac problem was present in 5 cases with 2 patients needing intensive care. The median time to diagnosis and treatment was 11.2 days, with all patients initially diagnosed erroneously. Current treatment guidelines were applied in 2 patients. Kawasaki disease in children over 8 years and adults under 30 years has a worse prognosis than in young children even though clinical features are atypical. It is rarely seen by clinicians in this age group, causing a delay in diagnosis, the main factor of the poor prognosis. The diagnosis of Kawasaki disease must be raised when predisposing factors are present in this group.
authors: Unité de médecine infantile, CHU la Timone-Enfants, 13385 Marseille cedex 5, France.
authors: V
authors: V
authors: Bresson
authors: B
authors: B
authors: Bonello
authors: C
authors: C
authors: Rousset-Rouvière
authors: J
authors: J
authors: Serratrice
authors: B
authors: B
authors: Chabrol
authors: J-C
authors: JC
authors: Dubus
authors: E
authors: E
authors: Bosdure