title: [Evaluation on the neointimal coverage post drug-eluting stent implantation by optical coherence tomography].
abstract: OBJECTIVE
  To assess the neointimal coverage after the implantation of various drug eluting stents (DES) by optical coherence tomography (OCT).
  
  
  METHODS
  The study comprised of 62 patients implanted DES for (15.3 ± 5.7) months. Patients were divided into three groups according to the type of implanted stent: Cypher group (patient = 26, stent = 57), Endeavor group (patient = 17, stent = 23) and Firebird group (patient = 19, stent = 32). OCT images of the stent were analyzed by software equipped by Light Lab system. Intimal thickness of 64 µm, 168 µm and 366 µm represents 10%, 25% and 50% lumen area loss, respectively. Neointimal coverage was thin with intimal thickness ≤ 64 µm, satisfactory with intimal thickness between 65 µm and 366 µm and hyperplasia and restenosis with intimal thickness > 366 µm.
  
  
  RESULTS
  The percent of complete neointimal coverage was similar among groups (P > 0.05). The thickness of neointimal coverage in Cypher and Endeavor and Firebird group was (178.7 ± 11.9) µm, (228.7 ± 17.1) µm and (170.3 ± 13.3) µm, respectively (all P < 0.05). The symmetry of Cypher stent was better than Firebird stent, and the symmetry of Firebird stent was better than Endeavor stent.
  
  
  CONCLUSIONS
  There was significant difference on neointimal coverage after various types of DES implantation, and OCT can be used to evaluate the symmetry of neointimal coverage post implantation of various DES.
authors: Cardiovascular Department, Chinese People's Liberation Army General Hospital, Beijing 100853, China.
authors: Feng
authors: F
authors: Tian
authors: Yun-Dai
authors: YD
authors: Chen
authors: Lian
authors: L
authors: Chen
authors: Zhi-Jun
authors: ZJ
authors: Sun
authors: Hong-Bin
authors: HB
authors: Liu
authors: Chang-Fu
authors: CF
authors: Liu
authors: Jun
authors: J
authors: Guo
authors: Jin-da
authors: JD
authors: Wang