title: Segmental vitiligo associated with generalized vitiligo (mixed vitiligo): a retrospective case series of 19 patients.
abstract: BACKGROUND
  Mixed vitiligo (MV), the association of segmental vitiligo (SV) and nonsegmental vitiligo, has been rarely reported.
  
  
  OBJECTIVE
  The aim of this study was to delineate the clinical spectrum of MV through a case series of patients with typical SV associated with patchy bilateral vitiligo.
  
  
  METHODS
  This was a cross-sectional evaluation in the setting of a prospective observational study conducted in the vitiligo clinic of the department of dermatology in Bordeaux, France.
  
  
  RESULTS
  Nineteen patients with MV were identified. Four were male and 15 were female. Most patients had an onset of SV before the age of 18 years (18 of 19). In all patients, SV preceded nonsegmental vitiligo with a delay ranging from 6 months to more than 24 months.
  
  
  CONCLUSIONS
  This study was cross-sectional and based on a single-center experience.
  
  
  CONCLUSIONS
  MV is not yet part of a conventional classification. However, this entity may have been neglected until now and should be included in the classification of vitiligo in addition to SV and nonsegmental vitiligo. Moreover, MV may be essential to the understanding of the pathogenesis of vitiligo as a primary skin disorder.
authors: Department of Dermatology and National Centre for Rare Skin Disorders, CHU St-André, Bordeaux, France. khaled.ezzedine@chu-bordeaux.fr
authors: Khaled
authors: K
authors: Ezzedine
authors: Yvon
authors: Y
authors: Gauthier
authors: Christine
authors: C
authors: Léauté-Labrèze
authors: Sonia
authors: S
authors: Marquez
authors: Serge
authors: S
authors: Bouchtnei
authors: Thomas
authors: T
authors: Jouary
authors: Alain
authors: A
authors: Taieb