title: 3-(1-Adamant-yl)-1-{[4-(2-meth-oxy-phen-yl)piperazin-1-yl]meth-yl}-4-methyl-1H-1,2,4-triazole-5(4H)-thione.
abstract: The title compound, C(25)H(35)N(5)OS, is a functionalized triazoline-3-thione with substituted piperazine and adamantyl substituents attached at the 2- and 5-positions, respectively, of a triazole spacer with an approximately C-shaped conformation of the mol-ecule. The piperazine ring adopts a chair conformation.
authors: Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
authors: Abdul-Malek S
authors: AM
authors: Al-Tamimi
authors: Ahmed
authors: A
authors: Bari
authors: Mohamed A
authors: MA
authors: Al-Omar
authors: Khalid A
authors: KA
authors: Alrashood
authors: Ali A
authors: AA
authors: El-Emam
references: Molecules. 2010 Apr 09;15(4):2526-50
references: 20428062
references: Toxicol Appl Pharmacol. 1969 Nov;15(3):642-65
references: 4982107
references: Eur J Med Chem. 2007 Jul;42(7):993-1003
references: 17321639
references: Arzneimittelforschung. 2006;56(1):40-7
references: 16478004
references: Acta Crystallogr Sect E Struct Rep Online. 2009 May 29;65(Pt 6):o1437
references: 21583277
references: Eur J Med Chem. 2007 Feb;42(2):235-42
references: 17129641
references: Acta Crystallogr A. 2008 Jan;64(Pt 1):112-22
references: 18156677
references: Antimicrob Agents Chemother. 1981 Feb;19(2):226-33
references: 7347558
references: Bioorg Med Chem. 2004 Oct 1;12(19):5107-13
references: 15351394