title: To what extent can preventive treatments prevent damage from systemic lupus erythematosus?
abstract: Managing lupus patients traditionally involves treating manifestations of active disease with the most effective and least toxic therapies so that "damage" from ongoing disease or treatments can be minimized. Damage in clinical epidemiologic studies is usually defined by the Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index, a validated, organ-specific assessment tool. This review summarizes recent developments regarding organ-specific manifestations and lupus-related damage and their prevention.
authors: Harvard Medical School, Center for Clinical Therapeutics, Division of Rheumatology, Brigham and Women's Hospital, Boston, MA 02115, USA. emassarotti@partners.org
authors: Elena M
authors: EM
authors: Massarotti
authors: Peter H
authors: PH
authors: Schur
references: Arthritis Care Res (Hoboken). 2010 Mar;62(3):393-400
references: 20391486
references: Arthritis Rheum. 2008 Dec 15;59(12):1796-804
references: 19035431
references: Autoimmun Rev. 2009 Feb;8(4):320-4
references: 18992852
references: Arthritis Care Res (Hoboken). 2011 Nov;63(11):1517-20
references: 22034113
references: Rheumatology (Oxford). 2009 May;48(5):542-5
references: 19233884
references: Ann Rheum Dis. 2008 Aug;67(8):1170-3
references: 18299303
references: Arthritis Rheum. 1996 Mar;39(3):363-9
references: 8607884
references: Ann Rheum Dis. 2008 Jun;67(6):829-34
references: 17875548
references: J Rheumatol. 2009 Dec;36(12):2691-3
references: 19884279
references: Arthritis Care Res (Hoboken). 2010 Aug;62(8):1160-5
references: 20235208
references: Clin Rheumatol. 2009 May;28(5):579-85
references: 19224131
references: J Rheumatol. 2008 Dec;35(12):2355-8
references: 19004040
references: Lupus. 2008 Mar;17(3):177-84
references: 18372357
references: Lupus. 2009 Dec;18(14):1303-8
references: 19850658
references: Lupus. 2009 Aug;18(9):822-30
references: 19578107
references: N Engl J Med. 2008 Nov 20;359(21):2195-207
references: 18997196
references: J Rheumatol. 2009 Mar;36(3):560-4
references: 19208608
references: Lupus. 2010 Jun;19(7):803-9
references: 20118159
references: Rheumatology (Oxford). 2007 Jul;46(7):1185-90
references: 17500075
references: Rheumatology (Oxford). 2009 Jun;48(6):673-5
references: 19359343
references: Semin Arthritis Rheum. 2008 Aug;38(1):41-54
references: 18221991
references: Arthritis Care Res (Hoboken). 2010 Apr;62(4):559-68
references: 20391512
references: Arthritis Rheum. 2007 Jul;56(7):2382-91
references: 17599766