title: [Constituents and bioactivities of Lamiophlomis rotata].
abstract: OBJECTIVE
  To investigate the chemical constituents from Lamiophlomis rotata and the bioactivities of 8-epideoxyloganic acid.
  
  
  METHODS
  The constituents were isolated by using a combination of various chromatographic techniques including column chromatography over ployamide, silica gel and Sephadex LH-20. Structures of the isolates were identified by spectroscopic data analysis. Bioactivities were screened by using models in vivo.
  
  
  RESULTS
  Five constituents were isolated. 8-epideoxyloganic acid was isolated for the first time in L. rotata and also in lamioplomis genus. 8-epideoxyloganic acid could significantly inhibit aectic acid-induced twisting times and slower the time of homeostatsis, also inhibit xylene-induced ear edema in mice.
  
  
  CONCLUSIONS
  8-epideoxyloganic acid possesses bioactivities of analgesia, homeostasis and anti-inflammatory.
authors: Liaoning Institute for Food and Drug Control, Shenyang 110023, China.
authors: Yanjun
authors: Y
authors: Hao
authors: Lin
authors: L
authors: Li
authors: Chen
authors: C
authors: Chen
authors: Yuli
authors: Y
authors: Sang