title: Mast-cell frequency within tumor correlates to the stage of tongue cancer.
abstract: Hydrolytic enzymes and angiogenic signals produced from mast cells have been suggested to be involved in the ability of tumours to invade normal tissues. In an approach to further test the hypothesis of the potential importance of mast cells in tumour growth we have compared the frequency of mast cells in tumour specimens from squamous cell carcinoma of the tongue stage T1 and T4. The results demonstrated a correlation of the frequency of mast cells within tumour with the stage of tongue cancer. No statistical correlation were found between mast cell frequency and grade of malignancy or spread to lymph nodes. Thus, further studies regarding the importance of mast cells in malignancy are of interest.
authors: UMEA UNIV,DEPT LUNG MED,S-90185 UMEA,SWEDEN. UMEA UNIV,DEPT OTORHINOLARYNGOL,S-90185 UMEA,SWEDEN. UMEA UNIV,DEPT HISTOL,S-90185 UMEA,SWEDEN.
authors: R
authors: R
authors: Henriksson
authors: L
authors: L
authors: Bjermer
authors: O
authors: O
authors: Frojd
authors: L
authors: L
authors: Franzen
authors: H
authors: H
authors: Gustafsson