title: [Developments in research of local bisphosphonate delivery system of implant denture].
abstract: Dental implant is an advanced prosthodontic treatment widely accepted by patients with missing tooth. However, peri-implant bone loss is still an important reason which limits wider application of the implants to a certain extent. Bisphosphonates is an osteoclastic bone resorption inhibitor that is widely used in clinical practice with the function of inhibiting bone resorption and increasing bone density. As the defect of systemic BPs treatment, local application of BPs in implant has become a research hotspot recently. Calcium phosphate ceramics, polylactic acid, fibrinogen film and collagen membrane have been reported as BPs carriers. This article summarizes the researches on the mechanism of bone regulation and local delivering system of BPs.
authors: West China College of Stomatology, Sichuan University, Chengdu 610041, China.
authors: Chengcheng
authors: C
authors: Zang
authors: Junjiang
authors: J
authors: Zhai
authors: Yanhua
authors: Y
authors: Meng
authors: Xing
authors: X
authors: Liang