title: Disseminated intravascular coagulation in a man with metachronous bone metastasis from gastric-cancer - case-report.
abstract: We report on a case of multiple bone metastasis and disseminated intravascular coagulation (DIG) in a 49-year-old Japanese man. He underwent total gastrectomy for advanced gastric cancer in July 1992, He was diagnosed as a case of multiple bone metastasis in August 1993. Severe anemia, thrombocytopenia, and elevated fibrinogen degradative products were indicative of DIG. He was treated with sequential i.v. administration of methotrexate (MTX) and 5-fluorouracil (5-FU) and continuous i.v. infusion of heparin and gabexate mesilate. After two weeks of treatment with MTX combined with 5-FU, the findings of DIC disappeared and his general condition improved dramatically.
authors: KYUSHU UNIV,FAC MED,DEPT SURG 2,HIGASHI KU,FUKUOKA 812,JAPAN. KYUSHU UNIV HOSP,CTR CANC,FUKUOKA 812,JAPAN.
authors: M
authors: M
authors: Yamamoto
authors: H
authors: H
authors: Baba
authors: T
authors: T
authors: Kusumoto
authors: K
authors: K
authors: Endo
authors: Y
authors: Y
authors: Maehara
authors: K
authors: K
authors: Sugimachi