title: Cri du chat syndrome after preimplantation genetic diagnosis for reciprocal translocation.
abstract: OBJECTIVE
  To report the first case of cri du chat syndrome after preimplantation genetic diagnosis (PGD) for reciprocal translocation.
  
  
  METHODS
  Case report.
  
  
  METHODS
  In vitro fertilization center in a university affiliated hospital.
  
  
  METHODS
  A woman carrying a t(11;22)(q23;q11.2) translocation.
  
  
  METHODS
  Preimplantation genetic diagnosis was performed, and the woman became pregnant.
  
  
  METHODS
  Successful PGD for reciprocal translocation and diagnosis of Cri du chat syndrome for the baby.
  
  
  RESULTS
  A male baby was born at 36 weeks' gestation. However, the baby presented with a high-pitched, cat-like cry. Cytogenetic study revealed a rare case of cri du chat syndrome associated with t(11;22)(q23;q11.2) translocation.
  
  
  CONCLUSIONS
  Chromosomal abnormalities, including the rare cru du chat syndrome, may occur after fluorescent in situ hybridization-based preimplantation genetic diagnosis.
authors: Department of Reproductive Endocrinology, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, People's Republic of China.
authors: Yinghui
authors: Y
authors: Ye
authors: Yuqin
authors: Y
authors: Luo
authors: Yuli
authors: Y
authors: Qian
authors: Chenming
authors: C
authors: Xu
authors: Fan
authors: F
authors: Jin