title: The role of surgical treatment in second primary lung cancer.
abstract: BACKGROUND
  This study was designed to assess the treatment of patients in whom a second primary lung cancer developed after the resection of primary lung cancer.
  
  
  METHODS
  Between January 1990 and December 2008, 1852 patients underwent complete resection for primary lung cancer in our institution. Of these individuals, patients who had been identified as having a second primary lung cancer by December 2009 were selected for this study using the criteria proposed by Martini and Melamed.
  
  
  RESULTS
  Of 1852 patients, a second primary lung cancer developed in 40 (2.2%) during the follow-up period. The overall 5-year and 10-year survival rates after the resection of the first tumor were 78.3% and 39.9%, respectively. The overall 5-year survival rate from the time of detection of the second primary lung cancer was 47.8%, and the 5-year survival rate of the patients who underwent resection of the second tumor was 77.0%. The patients who underwent sublobar resection had comparable overall survival and disease-free survival compared with the patients who underwent anatomic resection. Additionally, the patients who underwent sublobar resection had a better operative outcome.
  
  
  CONCLUSIONS
  Surgical resection is feasible and effective in the management of second primary lung cancer, and sublobar resection may be adequate. Long-term surveillance of more than 5 years is essential for early detection to increase the chance of resection of a second primary lung cancer.
authors: Department of Thoracic and Cardiovascular Surgery, Yonsei University College of Medicine, South Korea, and National University Hospital, Seoul, South Korea.
authors: Mi Kyung
authors: MK
authors: Bae
authors: Chun Sung
authors: CS
authors: Byun
authors: Chang Young
authors: CY
authors: Lee
authors: Jin Gu
authors: JG
authors: Lee
authors: In Kyu
authors: IK
authors: Park
authors: Dae Joon
authors: DJ
authors: Kim
authors: Kyung Young
authors: KY
authors: Chung