title: Reduction of hydrazines to amines with aqueous solution of titanium(III) trichloride.
abstract: N-N bond cleavage in hydrazines is widely used in the preparation of amines and thus occupies a significant place in organic synthesis. In this paper, we report a new method for the reductive cleavage of N-N bonds in hydrazines by commercially available and cheap aqueous titanium(III) trichloride. The reaction proceeds smoothly under a broad pH range from acidic to neutral and basic conditions to afford amines in good yields. This method is compatible with substrates containing functionalities such as C-C double bonds, benzyl-nitrogen bonds, benzyloxy and acyl groups.
authors: Key Laboratory of Green Chemistry and Technology of Ministry of Education, College of Chemistry, Sichuan University, Chengdu 610064, PR China.
authors: Yan
authors: Y
authors: Zhang
authors: Qiang
authors: Q
authors: Tang
authors: Meiming
authors: M
authors: Luo