title: Eye position effects in oculomotor plasticity and visual localization.
abstract: For visual localization to remain accurate across changes of gaze, a signal representing the position of the eye in the orbita is needed to code spatial locations in a reference frame that is independent of retinal displacements. Here we report evidence that the localization of visual objects in space is coded in an extraretinal reference frame. In human subjects, we used outward saccadic adaptation, which can be induced artificially by a systematic displacement of the saccade target. This form of oculomotor plasticity is accompanied by changes in spatial perception, thus highlighting the relevance of saccade metrics for visual localization. We tested the reference frame of outward adaptation for reactive and scanning saccades and visual localization. For scanning saccades, adaptation magnitude was drastically reduced at positions distant from the adapted eye position. Changes in visual localization showed a very similar modulation of eye position. These results suggest that scanning saccade adaptation is encoded in a nonretinotopic reference frame. Eye position effects for reactive saccade adaptation were smaller, and the induced mislocalization did not vary significantly between eye positions. The different modulation of reactive and scanning saccade adaptation supports the idea that oculomotor plasticity can occur at multiple sites in the brain. The findings are also consistent with previous evidence for a stronger influence of scanning saccade adaptation on the visual localization of objects in space.
authors: Department of Psychology, Università degli Studi di Firenze, 50135 Florence, Italy. eckartzi@gmail.com
authors: Eckart
authors: E
authors: Zimmermann
authors: Markus
authors: M
authors: Lappe
references: J Exp Psychol Hum Percept Perform. 1989 May;15(2):249-58
references: 2525598
references: Exp Brain Res. 1993;96(2):221-9
references: 8270019
references: Eur J Neurosci. 2001 Aug;14(3):554-60
references: 11553305
references: Curr Biol. 2003 Apr 1;13(7):585-9
references: 12676090
references: J Neurophysiol. 2005 Jun;93(6):3605-14
references: 15843478
references: J Neurosci. 2010 Jun 30;30(26):8882-7
references: 20592210
references: Exp Brain Res. 1993;93(1):157-64
references: 8467885
references: Philos Trans R Soc Lond B Biol Sci. 2011 Feb 27;366(1564):504-15
references: 21242139
references: Nature. 1998 Aug 27;394(6696):887-91
references: 9732870
references: J Vis. 2007 Dec 28;7(5):16.1-13
references: 18217856
references: Nat Neurosci. 2007 Feb;10(2):249-55
references: 17195842
references: Trends Neurosci. 2001 Feb;24(2):113-21
references: 11164942
references: J Neurophysiol. 2009 Mar;101(3):1550-9
references: 19091922
references: J Vis. 2010 Jun 01;10(6):2
references: 20884551
references: J Physiol. 2007 Jul 15;582(Pt 2):647-64
references: 17510192
references: Science. 1985 Oct 25;230(4724):456-8
references: 4048942
references: J Neurophysiol. 1997 Jul;78(1):567-71
references: 9242308
references: Vision Res. 1996 Jul;36(14):2087-98
references: 8776475
references: Exp Brain Res. 1992;90(2):302-6
references: 1397144
references: J Neurosci. 2009 Sep 2;29(35):11055-64
references: 19726664
references: J Neurophysiol. 1993 Nov;70(5):1741-58
references: 8294950
references: Vision Res. 1988;28(2):329-36
references: 3414020
references: J Neurophysiol. 1976 Nov;39(6):1246-56
references: 825620
references: Brain Res. 2007 Mar 2;1135(1):107-21
references: 17210146
references: Invest Ophthalmol Vis Sci. 2004 Jan;45(1):123-30
references: 14691163
references: Nature. 1999 Aug 26;400(6747):864-6
references: 10476963
references: Brain Res Cogn Brain Res. 2002 Feb;13(1):41-52
references: 11867249
references: J Neurosci. 2011 Jan 19;31(3):1059-68
references: 21248131
references: J Neurosci. 2010 Jul 21;30(29):9821-30
references: 20660264
references: J Neurosci. 1983 Mar;3(3):532-48
references: 6827308
references: Neurosci Lett. 2002 Nov 8;332(3):200-4
references: 12399014
references: Vision Res. 1995 Dec;35(23-24):3529-40
references: 8560817
references: Exp Brain Res. 1998 Feb;118(3):373-80
references: 9497144
references: Trends Cogn Sci. 2008 Dec;12(12):466-73
references: 18951831
references: J Neurophysiol. 1999 Jun;81(6):2798-813
references: 10368398
references: J Neurophysiol. 2007 Aug;98(2):602-12
references: 17553949
references: J Neurosci. 2008 Dec 17;28(51):13929-37
references: 19091981
references: Vision Res. 2010 Nov 23;50(23):2403-10
references: 20854833
references: Neurosci Biobehav Rev. 2010 Jul;34(8):1103-20
references: 20026351
references: J Neurophysiol. 1997 May;77(5):2268-92
references: 9163357
references: Exp Brain Res. 1994;100(2):293-306
references: 7813666
references: Eur J Neurosci. 1998 Jan;10(1):153-60
references: 9753122
references: Nature. 1995 May 18;375(6528):232-5
references: 7746323
references: Brain Res. 2007 Oct 3;1172:32-9
references: 17803970
references: Proc Natl Acad Sci U S A. 2008 May 20;105(20):7309-14
references: 18477700
references: Cereb Cortex. 2010 Jan;20(1):214-28
references: 19465740
references: Vision Res. 2006 Oct;46(21):3659-73
references: 16750239
references: Nat Neurosci. 2003 Aug;6(8):877-81
references: 12872128
references: J Neurosci. 2003 Jul 2;23(13):5446-54
references: 12843243
references: Prog Neurobiol. 2004 Jan;72(1):27-53
references: 15019175
references: J Neurosci. 2008 Apr 9;28(15):3988-99
references: 18400898