title: Stimulation of ALK by the growth factor midkine renders glioma cells resistant to autophagy-mediated cell death.
abstract: Δ⁹-tetrahydrocannabinol (THC), the main active component of marijuana, promotes cancer cell death via autophagy stimulation. We find that activation of the tyrosine kinase receptor ALK by its ligand midkine interferes with the signaling mechanism by which THC promotes autophagy-mediated glioma cell death.
authors: Department of Biochemistry and Molecular Biology I, School of Biology, Complutense University, Madrid, Spain.
authors: Mar
authors: M
authors: Lorente
authors: Sofia
authors: S
authors: Torres
authors: María
authors: M
authors: Salazar
authors: Arkaitz
authors: A
authors: Carracedo
authors: Sonia
authors: S
authors: Hernández-Tiedra
authors: Fátima
authors: F
authors: Rodríguez-Fornés
authors: Elena
authors: E
authors: García-Taboada
authors: Bárbara
authors: B
authors: Meléndez
authors: Manuela
authors: M
authors: Mollejo
authors: Yolanda
authors: Y
authors: Campos-Martín
authors: Juan A
authors: JA
authors: Barcia
authors: Manuel
authors: M
authors: Guzmán
authors: Guillermo
authors: G
authors: Velasco