title: A systematic review of quality of life in adults with muscle disease.
abstract: We reviewed the literature on how muscle disease affects quality of life compared to healthy controls, and the factors that influence the effects of muscle disease on quality of life. We also wanted to know whether quality of life differed between muscle diseases. We searched online databases and identified 26 relevant studies. The quality of each study was assessed, results sections analysed and a database of factors associated with quality of life developed. We graded the level of evidence supporting the association between each factor and quality of life as inconclusive, moderate or high. Compared to controls, muscle disease compromised quality of life in all areas of functioning. There was little evidence to suggest that quality of life differed significantly between muscle diseases. There was a high level of evidence suggesting that disease severity, pain, fatigue, and mood significantly affect quality of life. There was a moderate level of evidence suggesting that illness perceptions, coping strategies, age and gender affect quality of life. Several factors had an inconsistent level of evidence.
authors: Department of Psychology, Institute of Psychiatry, King's College London, 5th Floor Bermondsey Wing, Guy's Hospital, London, SE1 9RT, UK. christopher.graham@kcl.ac.uk
authors: Christopher D
authors: CD
authors: Graham
authors: Michael R
authors: MR
authors: Rose
authors: Elizabeth A
authors: EA
authors: Grunfeld
authors: Simon D
authors: SD
authors: Kyle
authors: John
authors: J
authors: Weinman
references: Ann Emerg Med. 1994 Apr;23(4):807-12
references: 8161051
references: Acta Neurol Scand. 2004 Feb;109(2):113-9
references: 14705973
references: J Neurol Neurosurg Psychiatry. 1998 Sep;65(3):353-6
references: 9728948
references: Muscle Nerve. 2009 Aug;40(2):200-5
references: 19609906
references: Am J Med Genet. 1995 Feb 27;60(1):33-8
references: 7485232
references: Neurology. 2007 Mar 27;68(13):1051-7
references: 17389311
references: Ann Rheum Dis. 2006 Nov;65(11):1456-61
references: 16606652
references: Psychosom Med. 2002 Jul-Aug;64(4):580-6
references: 12140347
references: Eur J Neurol. 2010 Sep;17(9):1178-1187
references: 20374278
references: Med Care. 1992 Jun;30(6):473-83
references: 1593914
references: Clin Neurophysiol. 2007 Feb;118(2):292-300
references: 17166763
references: J Rehabil Med. 2010 Jan;42(1):60-5
references: 20111846
references: Chest. 2001 Mar;119(3):940-6
references: 11243978
references: Qual Life Res. 1993 Feb;2(1):33-45
references: 8490616
references: Disabil Rehabil. 2000 Nov 20;22(17):776-85
references: 11194618
references: J Neurol Neurosurg Psychiatry. 2005 Oct;76(10):1406-9
references: 16170086
references: Arch Phys Med Rehabil. 2005 Jun;86(6):1155-63
references: 15954054
references: Health Qual Life Outcomes. 2007 Jun 06;5:31
references: 17553127
references: Int J Rehabil Res. 2005 Jun;28(2):103-9
references: 15900179
references: Soc Sci Med. 1999 Apr;48(8):977-88
references: 10390038
references: Am J Hosp Palliat Care. 2009 Aug-Sep;26(4):308-19
references: 19414560
references: Muscle Nerve. 2012 Sep;46(3):351-9
references: 22907225
references: Arch Phys Med Rehabil. 2008 Feb;89(2):320-8
references: 18226657
references: Med Care. 1981 Aug;19(8):787-805
references: 7278416
references: Neuromuscul Disord. 2009 Jun;19(6):397-402
references: 19403309
references: N Z Med J. 2006 Sep 08;119(1241):U2145
references: 16964297
references: Disabil Rehabil. 2001 Nov 20;23(17):788-98
references: 11762881
references: Clin Rehabil. 2005 Sep;19(6):686-94
references: 16180606
references: Phys Med Rehabil Clin N Am. 1998 Feb;9(1):233-48
references: 9894142
references: Neurosciences (Riyadh). 2009 Oct;14(4):355-9
references: 21048650
references: Am J Hosp Palliat Care. 2002 Jan-Feb;19(1):39-48
references: 12173612
references: J Neurol Neurosurg Psychiatry. 2010 Oct;81(10):1164-6
references: 20601666
references: J Am Acad Dermatol. 2006 Feb;54(2):217-20
references: 16443050
references: Chest. 1994 Jul;106(1):173-9
references: 8020268
references: Rheumatology (Oxford). 2002 Jan;41(1):22-6
references: 11792875
references: J Rehabil Med. 2001 Sep;33(5):206-11
references: 11585151
references: Acta Oncol. 2000;39(4):477-84
references: 11041109
references: Am J Respir Crit Care Med. 2005 Oct 15;172(8):1032-6
references: 15961695
references: J Neurol Neurosurg Psychiatry. 2000 Sep;69(3):308-12
references: 10945804
references: Rheumatology (Oxford). 2005 Jan;44(1):83-8
references: 15381789
references: J Psychosom Res. 2007 May;62(5):571-9
references: 17467412
references: Scand J Rehabil Med. 1996 Sep;28(3):147-57
references: 8885037
references: J Psychosom Res. 1996 Oct;41(4):365-76
references: 8971667
references: Neurology. 2007 Jul 24;69(4):342-7
references: 17581943
references: Soc Sci Med A. 1981 May;15(3 Pt 1):221-9
references: 6973203
references: J Rehabil Med. 2006 May;38(3):181-5
references: 16702085
references: Mov Disord. 2000 Nov;15(6):1112-8
references: 11104193
references: Soc Sci Med. 2000 Aug;51(3):419-27
references: 10855928