title: Investigation of glycosylating properties of 1-deoxy-1-ethoxysulfonyl-hept-2-ulopyranosyl derivatives. Synthesis of a new sulfonic acid mimetic of the sialyl Lewis X tetrasaccharide.
abstract: Glycosylation reactions of the ethylthio, bromo and chloro derivatives of 1-deoxy-1-ethoxysulfonyl-hept-2-ulopyranose were studied applying different acceptors under different conditions. Elimination side-reactions affording exo- and endoglycals occured in all cases, however, with different proportions. Glycosyl chloride donor was applied to glycosylate a trisaccharide acceptor obtaining a new sulfonic acid mimetic of the sialyl Lewis X tetrasaccharide in high yield.
authors: Research Group for Carbohydrates of Hungarian Academy of Sciences, PO Box 94, Debrecen H-4010, Hungary.
authors: Magdolna
authors: M
authors: Csávás
authors: Gábor
authors: G
authors: Májer
authors: Mihály
authors: M
authors: Herczeg
authors: Judit
authors: J
authors: Remenyik
authors: László
authors: L
authors: Lázár
authors: Attila
authors: A
authors: Mándi
authors: Anikó
authors: A
authors: Borbás
authors: Sándor
authors: S
authors: Antus