title: Chiral Lewis base-assisted Brønsted acid (LBBA)-catalyzed enantioselective cyclization of 2-geranylphenols.
abstract: Chiral Lewis base-assisted Brønsted acids (Chiral LBBAs) have been designed as new organocatalysts for biomimetic enantioselective cyclization. A salt of a chiral phosphonous acid diester with FSO(3)H catalyzes the enantioselective cyclization of 2-geranylphenols to give the desired trans-fused cyclized products with high diastereo- and enantioselectivities (up to 98:2 dr and 93% ee).
authors: EcoTopia Science Institute, Graduate School of Engineering, Nagoya University, Chikusa, Nagoya, 464-8603, Japan.
authors: Akira
authors: A
authors: Sakakura
authors: Masayuki
authors: M
authors: Sakuma
authors: Kazuaki
authors: K
authors: Ishihara