title: Developing a matrix to identify and prioritise research recommendations in HIV prevention.
abstract: BACKGROUND
  HIV prevention continues to be problematic in the UK, as it does globally. The UK Department of Health has a strategic direction with greater focus on prevention as part of its World Class Commissioning Programme. There is a need for targeted evidence-based prevention initiatives. This is an exploratory study to develop an evidence mapping tool in the form of a matrix: this will be used to identify important gaps in contemporary HIV prevention evidence relevant to the UK. It has the potential to aid prioritisation in future research.
  
  
  METHODS
  Categories for prevention and risk groups were developed for HIV prevention in consultation with external experts. These were used as axes on a matrix tool to map evidence. Systematic searches for publications on HIV prevention were undertaken using electronic databases for primary and secondary research undertaken mainly in UK, USA, Canada, Australia and New Zealand, 2006-9. Each publication was screened for inclusion then coded. The risk groups and prevention areas in each paper were counted: several publications addressed multiple risk groups. The counts were exported to the matrix and clearly illustrate the concentrations and gaps of literature in HIV prevention.
  
  
  RESULTS
  716 systematic reviews, randomised control trials and other primary research met the inclusion criteria for HIV prevention. The matrix identified several under researched areas in HIV prevention.
  
  
  CONCLUSIONS
  This is the first categorisation system for HIV prevention and the matrix is a novel tool for evidence mapping. Some important yet under-researched areas have been identified in HIV prevention evidence: identifying the undiagnosed population; international adaptation; education; intervention combinations; transgender; sex-workers; heterosexuals and older age groups.
authors: National Institute for Health Research, Evaluation, Trials and Studies Coordinating Centre, Health Technology Assessment, University of Southampton, Southampton, SO16 7NS, UK. S.anstee@southampton.ac.uk
authors: Sydney
authors: S
authors: Anstee
authors: Alison
authors: A
authors: Price
authors: Amanda
authors: A
authors: Young
authors: Katharine
authors: K
authors: Barnard
authors: Bob
authors: B
authors: Coates
authors: Simon
authors: S
authors: Fraser
authors: Rebecca
authors: R
authors: Moran
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