title: Hydrogen bond assisted activation of a dinitrile towards nucleophilic attack.
abstract: The possibility of tunable regioselective activation of a dinitrile towards nucleophilic attack was demonstrated. For that, a sulfo-arylhydrazone unit was introduced into malononitrile and the thus formed intramolecular hydrogen bond systems assisted specific nucleophilic attacks to the cyano moieties leading to a variety of amidines, carboxamides and iminoesters depending on the nucleophiles and conditions used.
authors: Centro Química Estrutural, Complexo I, Instituto Superior Técnico, TU Lisbon, Av. Rovisco Pais, 1049-001, Lisbon, Portugal.
authors: Maximilian N
authors: MN
authors: Kopylovich
authors: Kamran T
authors: KT
authors: Mahmudov
authors: Archana
authors: A
authors: Mizar
authors: Armando J L
authors: AJ
authors: Pombeiro