title: Peoscopic diagnosis of flat condyloma and penile intraepithelial neoplasia V scrotal reservoir.
abstract: The aim of the present study was to evaluate prospectively male sexual partners of women with flat condyloma (FC) or accuminata (CA) or cervical intraepithelial neoplasia (CIN) and to determine the incidence of scrotal involvement by HPV. Of the 218 patients, 20 (9.17%) revealed areas of acetowhite epithelium involving the anterior lateral and superior aspects of the scrotum. Eight patients (40%) also presented concomitant small telangiectatic lesions measuring 1-3 mm of the scrotum in the acetowhite areas, and one patient presented scrotal intraepithelial neoplasia grade I (SIN I). The new combination treatment schedule (cream 5-fluorouracil 5% + Interferon alpha-2 alpha) resulted in a 100% cure rate, with no recurrences for the follow-up period (11.52 months). Concluding, the scrotum appears to be an important and presently overlooked area in the evaluation of male patients, and interferon in combination with 5-FU cream seems to be a promising treatment for HPV infection.
authors: UNIV PATRAS,DEPT OBSTET & GYNECOL,PATRAS,GREECE. UNIV HERAKLION,DEPT OBSTET & GYNECOL,IRAKLION,GREECE. H VENIZELOU MATERN HOSP,DEPT OBSTET & GYNECOL 2,ATHENS,GREECE. ATHENS NAVAL HOSP,DEPT PATHOL,ATHENS,GREECE. EUROMED MED INST,ATHENS,GREECE.
authors: K
authors: K
authors: Relakis
authors: E
authors: E
authors: Cardamakis
authors: I
authors: I
authors: Kotoulas
authors: E
authors: E
authors: Stathopoulos
authors: A
authors: A
authors: Korantzis
authors: K
authors: K
authors: Metalinos
authors: H
authors: H
authors: Mantouvalos
authors: V
authors: V
authors: Tzingounis
authors: E
authors: E
authors: Koumantakis