title: Levocetirizinium dipicrate.
abstract: There are two cation-dianion pairs in the asymmetric unit of the title compound, C(21)H(27)ClN(2)O(3) (2+)·2C(6)H(2)N(3)O(7) (-) {systematic name: 1-[2-(carb-oxy-meth-oxy)eth-yl]-4-[(R)-(4-chloro-phen-yl)phenyl-meth-yl]piperazine-1,4-diium bis-(2,4,6-trinitro-phenol-ate)}. The piperazine group in the levocetirizinium cation is protonated at both N atoms. The acetyl end groups form R(2) (2)(8) hydrogen-bonded motifs with adjacent cations. Each picrate anion inter-acts with the proponated N atom in the cation through a bifurcated N-H⋯O hydrogen bond, forming R(1) (2)(6) ring motifs. Strong and weak inter-molecular N-H⋯O and strong O-H⋯O hydrogen bonds, and weak π-ring and π-π stacking inter-actions [centroid-centroid distance = 3.7419 (14) Å] dominate the crystal packing, creating a three-dimensional supra-molecular structure.
authors: Jerry P
authors: JP
authors: Jasinski
authors: Ray J
authors: RJ
authors: Butcher
authors: M S
authors: MS
authors: Siddegowda
authors: H S
authors: HS
authors: Yathirajan
authors: A R
authors: AR
authors: Ramesha
references: Drugs. 2006;66(7):973-96
references: 16740020
references: Acta Crystallogr Sect E Struct Rep Online. 2009 Jul 01;65(Pt 8):o1738-9
references: 21583452
references: Acta Crystallogr Sect E Struct Rep Online. 2010 Jan 20;66(Pt 2):o411-2
references: 21579830
references: Acta Crystallogr Sect E Struct Rep Online. 2010 Jan 13;66(Pt 2):o347-8
references: 21579775
references: Acta Crystallogr A. 2008 Jan;64(Pt 1):112-22
references: 18156677