title: Infantile fibrosarcoma: retrospective analysis of eleven patients.
abstract: OBJECTIVE
  Infantile fibrosarcomas are soft tissue sarcomas that are diagnosed at or soon after birth. In the present study, we retrospectively evaluated clinical characteristics, treatment modalities and outcome of patients diagnosed with infantile fibrosarcoma at our institution.
  
  
  METHODS
  A retrospective review was conducted to evaluate demographic characteristics, presenting features, type and timing of surgery, other treatment modalities and survival characteristics.
  
  
  RESULTS
  Nine males and 2 females were diagnosed with infantile fibrosarcoma between 1970-2008. The initial surgical procedure was subtotal resection in 4 patients, gross-total resection in 3 and biopsy in 4. Neoadjuvant chemotherapy was given to 10 patients. Three patients died, one for the disease and 2 from complications of therapy. Eight patients are under follow-up with no evidence of disease for 1.3 to 13.5 years. None of the patients in the series underwent amputation.
  
  
  CONCLUSIONS
  Owing to the chemosensitive nature of the tumor and possibility of spontaneous regression, neoadjuvant chemotherapy should be considered to prevent extensive or mutilating surgery.
authors: Hacettepe University, Institute of Oncology, Department of Pediatric Oncology, Ankara, Turkey.
authors: Canan
authors: C
authors: Akyüz
authors: Serhan
authors: S
authors: Küpeli
authors: Ali
authors: A
authors: Varan
authors: Gökhan
authors: G
authors: Gedikoglu
authors: Bilgehan
authors: B
authors: Yalçin
authors: Tezer
authors: T
authors: Kutluk
authors: Münevver
authors: M
authors: Büyükpamukçu