title: Negative correlation between aqueous vascular endothelial growth factor levels and axial length.
abstract: OBJECTIVE
  The aim of this study was to evaluate the relationship between the concentrations of vascular endothelial growth factor (VEGF) in the aqueous humor and axial length.
  
  
  METHODS
  Aqueous humor samples were obtained from 60 eyes of 60 patients without ocular diseases other than cataracts. No patients with diabetes mellitus were included. The VEGF concentration in the aqueous humor was measured using an enzyme-linked immunosorbent assay.
  
  
  RESULTS
  The VEGF concentrations in the aqueous humor samples ranged from 25 to 241 pg/ml [mean ± standard deviation (SD), 116.6 ± 46.7 pg/ml]. The axial lengths ranged from 20.98 to 31.95 mm (mean ± SD, 24.09 ± 2.06 mm). The VEGF concentrations in the aqueous humor samples were correlated with axial length (Pearson product moment correlation test, ρ = -0.373; P = 0.003).
  
  
  CONCLUSIONS
  The concentration of VEGF in the aqueous humor is negatively correlated with axial length.
authors: Department of Ophthalmology, Shiga University of Medical Science, Seta Tsukinowacho, Otsu, Shiga, 520-2192, Japan. osawada@belle.shiga-med.ac.jp.
authors: Osamu
authors: O
authors: Sawada
authors: Department of Ophthalmology, Shiga University of Medical Science, Seta Tsukinowacho, Otsu, Shiga, 520-2192, Japan.
authors: Taichiro
authors: T
authors: Miyake
authors: Department of Ophthalmology, Shiga University of Medical Science, Seta Tsukinowacho, Otsu, Shiga, 520-2192, Japan.
authors: Masashi
authors: M
authors: Kakinoki
authors: Department of Ophthalmology, Shiga University of Medical Science, Seta Tsukinowacho, Otsu, Shiga, 520-2192, Japan.
authors: Tomoko
authors: T
authors: Sawada
authors: Department of Ophthalmology, Shiga University of Medical Science, Seta Tsukinowacho, Otsu, Shiga, 520-2192, Japan.
authors: Hajime
authors: H
authors: Kawamura
authors: Department of Ophthalmology, Shiga University of Medical Science, Seta Tsukinowacho, Otsu, Shiga, 520-2192, Japan.
authors: Masahito
authors: M
authors: Ohji
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