title: Prevention of liver-tumor colonization by combined immunomodulation and liver lectin blocking.
abstract: The protective effect of combined treatment (immunomodulation with Propionibacterium avidum KP-40; liver lectin blocking by D-galactose administration) on the liver colonization of RAW 117-H10 lymphosarcoma was investigated in BALB/c-mice. Both, immunomodulation with P. avidum KP-40 as well as liver lectin blocking by D-galactose treatment significantly decreased the number of liver tumor colonies in this experimental model. However, the combination of P. avidum KP-40 and D-galactose obviously proved to be superior to each monotherapy since the liver colonization by RAW 117-H 10 lymphosarcoma could be completely inhibited.
authors: UNIV COLOGNE,INST MED MICROBIOL & HYG,GOLDENFELSSTR 19-21,D-50935 COLOGNE,GERMANY.
authors: G
authors: G
authors: Pulverer
authors: H
authors: H
authors: Ko
authors: J
authors: J
authors: Beuth