title: Diagnostic-significance of liver-failure after newly-appeared serum fractions following liver surgery.
abstract: We investigated a serum marker suggesting postoperative liver failure based on basic research. In diseased Long Evans Cinnamon rat with spontaneous development of hepatitis and hepatocellular carcinoma, the specific fractions, Fr 43 (peak-1) and Fr 58-60 (peak-2), newly appeared in the eluted serum following highperformance liquid chromatography. Peak-1 was associated with progressing Liver damage or failure. We applied this theory to five patients undergoing liver surgery and our expectations were realized. Peak-1 was probably a certain hepatic regenerating factor recognized in a previous study and we suspected that the exessive production of a liver regenerating factor signified an ongoing liver failure.
authors: HOKKAIDO UNIV,SCH MED,INST CANC,DEPT CELL BIOL,SAPPORO,HOKKAIDO 060,JAPAN. HOKKAIDO UNIV,SCH MED,DEPT SURG 1,SAPPORO,HOKKAIDO 060,JAPAN.
authors: T
authors: T
authors: Namieno
authors: N
authors: N
authors: Takeichi
authors: Y
authors: Y
authors: Hata
authors: J
authors: J
authors: Uchino