title: mirAct: a web tool for evaluating microRNA activity based on gene expression data.
abstract: MicroRNAs (miRNAs) are critical regulators in the complex cellular networks. The mirAct web server (http://sysbio.ustc.edu.cn/software/mirAct) is a tool designed to investigate miRNA activity based on gene-expression data by using the negative regulation relationship between miRNAs and their target genes. mirAct supports multiple-class data and enables clustering analysis based on computationally determined miRNA activity. Here, we describe the framework of mirAct, demonstrate its performance by comparing with other similar programs and exemplify its applications using case studies.
authors: Hefei National Laboratory for Physical Sciences at Microscale and School of Life Science, University of Science and Technology of China, 96 Jinzhai Road, Hefei, Anhui 230027, China. liangzhi@ustc.edu.cn
authors: Zhi
authors: Z
authors: Liang
authors: Hong
authors: H
authors: Zhou
authors: Zongxiao
authors: Z
authors: He
authors: Haoran
authors: H
authors: Zheng
authors: Jiarui
authors: J
authors: Wu
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