title: Studies of a furanoside as antimycobacterial agent loaded into a biodegradable PBAT/sodium caseinate support.
abstract: An improved synthesis of n-octyl β-D-galactofuranoside was described using micro-wave activation. The resulting alkyl furanoside showed antibacterial activity against Mycobacterium smegmatis, a non-pathogenic model of Mycobacterium tuberculosis. It was further incorporated into a biodegradable PBAT/sodium caseinate polymer. The resulting biomaterial loaded with 5% of the pharmacophore retained the mycobacteriostatic properties and developed a mycobactericidal activity on contact and at the periphery of the film.
authors: Ecole Nationale Supérieure de Chimie de Rennes, CNRS, UMR 6226, Avenue du Général Leclerc, CS 50837, 35708 Rennes Cedex 7, France. vincent.ferrieres@ensc-rennes.fr
authors: Laurent
authors: L
authors: Legentil
authors: Jean-Luc
authors: JL
authors: Audic
authors: Richard
authors: R
authors: Daniellou
authors: Caroline
authors: C
authors: Nugier-Chauvin
authors: Vincent
authors: V
authors: Ferrières