title: Clinical practice and outcome of radiotherapy for esophageal cancer between 1999 and 2003: the Japanese Radiation Oncology Study Group (JROSG) Survey.
abstract: BACKGROUND
  To determine the clinical results of radiotherapy (RT) for esophageal cancer in Japan.
  
  
  METHODS
  A questionnaire-based survey was conducted for esophageal cancer treated by definitive RT between 1999 and 2003. Clinical results of definitive RT for patients were collected from 9 major institutions. Only patients with good performance status (PS 0-2) who received a total dose of 50 Gy or more were included. Patients were classified into three groups: (A) stage I, (B) resectable stages II-III, (C) unresectable stages III-IVA. For group A, all patients treated by RT alone or chemo-radiotherapy (CRT) were included. For groups B and C, only those treated by CRT were included.
  
  
  RESULTS
  In total, 167 patients were included in group A, 239 in group B, and 244 in group C. Approximately half of the patients in group A were treated by CRT. The median total RT dose ranged from 60 to 66 Gy. The median and range of the 5-year overall survival rates were 56% (48-83%) for group A, 29% (12-52%) for group B, and 19% (0-31%) for group C, respectively. A wide disparity in overall survival rates was noted among the institutions. A significant correlation between the number of patients treated per year and the 5-year overall survival rate was noted for groups B and C (both p < 0.05).
  
  
  CONCLUSIONS
  Although the overall survival rates for stage I esophageal cancer were excellent, a significant disparity in survival rates was noted among the institutions for stage II-IVA tumors treated by CRT.
authors: Department of Radiation Oncology, Kinki University Faculty of Medicine, Ohno-Higashi, Osaka-Sayama, Osaka, 589-8511, Japan. ynishi@med.kindai.ac.jp
authors: Yasumasa
authors: Y
authors: Nishimura
authors: Ryuta
authors: R
authors: Koike
authors: Kazuhiko
authors: K
authors: Ogawa
authors: Ryuta
authors: R
authors: Sasamoto
authors: Yuji
authors: Y
authors: Murakami
authors: Yoshiyuki
authors: Y
authors: Itoh
authors: Yoshiharu
authors: Y
authors: Negoro
authors: Satoshi
authors: S
authors: Itasaka
authors: Toru
authors: T
authors: Sakayauchi
authors: Tetsuro
authors: T
authors: Tamamoto
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