title: Isolation and characterization of atropisomers of seven-membered-ring benzolactams.
abstract: The atropisomeric properties of seven-membered-ring benzolactams (7a-c and 8a) [1,5-benzodiazepin-2-one (a), 1,5-benzothiazepin-4-one (b), and 1-benzazepin-2-one (c)] were examined. The atropisomers were isolated as the diastereomers with an (S)-phenethylamide moiety, which were characterized by X-ray crystallography, and the barriers to their interconversion were clarified.
authors: School of Pharmaceutical Sciences, Teikyo University, 1091-1, Midori-ku, Sagamihara, Kanagawa 252-5195, Japan.
authors: Hidetsugu
authors: H
authors: Tabata
authors: Naoya
authors: N
authors: Wada
authors: Yuko
authors: Y
authors: Takada
authors: Tetsuta
authors: T
authors: Oshitari
authors: Hideyo
authors: H
authors: Takahashi
authors: Hideaki
authors: H
authors: Natsugari