title: Ethyl 5,8-dibromo-2-dibromo-methyl-6,7-dimeth-oxyquinoline-3-carb-oxy-late.
abstract: The title compound, C(15)H(13)Br(4)NO(4), was obtained via radical bromination reaction of ethyl 6,7-dimeth-oxy-2-methyl-quinoline-3-carboxyl-ate and N-bromo-succinimide (NBS) in the presence of benzoyl peroxide (BPO) under photocatalytic conditions. The quinoline ring system is approximately planar with a maximum deviation from the mean plane of 0.035 (1) Å. The dihedral angle between the six-membered rings is 2.33 (2)°. The meth-oxy O atoms of the two neighboring meth-oxy groups are in-plane while their methyl C atoms are located on either side of the quinolyl ring plane at distances of -1.207 (1) and 1.223 (1) Å.
authors: School of Chemistry and Environment, South China Normal University, Guangzhou 510006, People's Republic of China.
authors: Ting
authors: T
authors: Zhou
authors: Yu-Hua
authors: YH
authors: Long
authors: Ding-Qiao
authors: DQ
authors: Yang
authors: Han-Mei
authors: HM
authors: Zhang
authors: Wen-Ling
authors: WL
authors: Wang
references: Bioorg Med Chem Lett. 2001 Feb 12;11(3):279-82
references: 11212091
references: Acta Crystallogr D Biol Crystallogr. 2009 Feb;65(Pt 2):148-55
references: 19171970
references: Bioorg Med Chem Lett. 2004 Oct 4;14(19):4867-72
references: 15341941
references: Nat Prod Rep. 2002 Dec;19(6):742-60
references: 12521267
references: Biochem Biophys Res Commun. 2004 Oct 8;323(1):264-8
references: 15351731
references: Acta Crystallogr A. 2008 Jan;64(Pt 1):112-22
references: 18156677