title: Antiviral isoindolone derivatives from an endophytic fungus Emericella sp. associated with Aegiceras corniculatum.
abstract: Chemical investigation of the endophytic fungus Emericella sp. (HK-ZJ) isolated from the mangrove plant Aegiceras corniculatum led to isolation of six isoindolones derivatives termed as emerimidine A and B and emeriphenolicins A and D, and six previously reported compounds named aspernidine A and B, austin, austinol, dehydroaustin, and acetoxydehydroaustin, respectively. Their structures were elucidated on the basis of NMR spectroscopic evidence while the anti-influenza A viral (H₁N₁) activities of eight compounds were also evaluated using the cytopathic effect (CPE) inhibition assay.
authors: Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, PR China.
authors: Guojian
authors: G
authors: Zhang
authors: Shiwei
authors: S
authors: Sun
authors: Tianjiao
authors: T
authors: Zhu
authors: Zhenjian
authors: Z
authors: Lin
authors: Jingyan
authors: J
authors: Gu
authors: Dehai
authors: D
authors: Li
authors: Qianqun
authors: Q
authors: Gu