title: Development of a fermented goats' milk containing Lactobacillus rhamnosus: in vivo study of health benefits.
abstract: BACKGROUND
  Lactobacillus rhamnosus CRL1505, a strain of goats' milk origin, is able to stimulate mucosal immunity and protect immunocompetent mice from intestinal and respiratory infections.
  
  
  RESULTS
  In this work we developed and characterized a fermented goats' milk containing L. rhamnosus CRL1505, and we demonstrated in a model of immunosuppression in mice that the final dairy product preserves the immunomodulatory properties of the strain. L. rhamnosus CRL1505 survived the manufacturing process of fermented milk and maintained a viability of 10(6) cfu g(-1) during storage. The fermented goats' milk was accepted by 90.48% of the panelists and was considered as having an acid taste and pleasant aroma. We also demonstrated that the developed product, used as a supplement during the repletion of immunocompromised malnourished mice, was effective in accelerating the recovery of clinical parameters altered by malnutrition and to induce increased resistance against intestinal and respiratory infections.
  
  
  CONCLUSIONS
  Goats' milk fermented with L. rhamnosus CRL1505 could be manufactured as an alternative probiotic dairy product since this new food has the ability to stimulate the common mucosal immune system and to improve defenses against respiratory and intestinal infections.
authors: Centro de Referencia para Lactobacilos (CERELA-CONICET), San Miguel de Tucumán, Tucumán, Argentina.
authors: Susana
authors: S
authors: Salva
authors: Martha
authors: M
authors: Nuñez
authors: Julio
authors: J
authors: Villena
authors: Adriana
authors: A
authors: Ramón
authors: Graciela
authors: G
authors: Font
authors: Susana
authors: S
authors: Alvarez