title: [Occluding effects of three new calcium desensitizers on dentinal tubules in vitro].
abstract: OBJECTIVE
  To evaluate the occluding effects of three new calcium desensitizers on dentinal tubules in vitro.
  
  
  METHODS
  Twenty-five dentin specimens of 1.00 mm thick from freshly extracted third molars were divided into five groups randomly. After treatment with 6% citric acid, group A was treated with distilled water, and group B-E were treated with NovaMin, Pro-Argin, casein phosphopeptide-amorphous calcium phosphate (CPP-ACP), and 75% NaF glycerin for 2 min respectively. Then the teeth were vertically cleaved into two sections. The surfaces and cross sections were observed by the scanning electron microscope (SEM) and energy dispersive X-ray (EDX), which were analyzed by the Image-Pro Plus software.
  
  
  RESULTS
  The percentage of dentin tubules sealed were (81.6 ± 6.1)%, (71.5 ± 6.3)%, (43.2 ± 2.6)%, (39.9 ± 4.1)% for groups B, C, D and E respectively, and the occluding depth were (30.33 ± 2.26), (24.55 ± 2.58), (16.10 ± 4.65) and (8.90 ± 1.51) µm respectively. The differences between these groups were statistically significant (P < 0.01) except for group B and C (P > 0.05). However, there was no significant difference between all the groups for the Ca/P ratios (P = 0.342).
  
  
  CONCLUSIONS
  NovaMin may have better immediate occluding effects than other desensitizers and could deposit a dentin-like mineral.
authors: Institute of Stomatology, Nanjing Medical University & Department of Prosthodontics, Affiliated Hospital of Stomatology, Nanjing Medical University, Nanjing 210029, China.
authors: Zheng-hui
authors: ZH
authors: Xiong
authors: Lu
authors: L
authors: Xia
authors: Lei
authors: L
authors: Mei
authors: Guang-zheng
authors: GZ
authors: Han
authors: Ya-ming
authors: YM
authors: Chen