title: The liver: another organ involved in Muir Torre syndrome?
abstract: Muir Torre syndrome is a rare autosomal dominant cancer-predisposing syndrome characterized by the occurrence of sebaceous gland neoplasms and/or keratoacanthomas associated with visceral malignancies that belong to the spectrum of hereditary non polyposis colorectal cancer (HNPCC), i.e., tumors of gastrointestinal and genitourinary tracts. Hepatobiliary malignancy in association with Muir Torre syndrome has rarely been reported. Here, we describe a case of Muir Torre syndrome associated with an hepatocellular-carcinoma in a patient with a non-cirrhotic liver and an HNPCC-family with multiple cases of hepatocellular carcinoma.
authors: Department of Clinical and Experimental Medicine, University of Padova, Via Giustiniani 2, 35128, Padova, Italy.
authors: F
authors: F
authors: Morando
authors: M
authors: M
authors: Alaibac
authors: A
authors: A
authors: Romano
authors: M
authors: M
authors: Cavallin
authors: S
authors: S
authors: Piano
authors: M
authors: M
authors: Pizzi
authors: C
authors: C
authors: Mescoli
authors: P
authors: P
authors: Pilati
authors: A
authors: A
authors: Gatta
authors: P
authors: P
authors: Angeli
references: N Engl J Med. 2003 Mar 6;348(10):919-32
references: 12621137
references: Clin Genet. 2005 Nov;68(5):442-7
references: 16207212
references: Am J Med. 1991 May;90(5):606-13
references: 2029018
references: Int J Oncol. 2001 Sep;19(3):567-70
references: 11494037
references: Cancer. 2008 Dec 15;113(12):3372-81
references: 18932259
references: J Am Acad Dermatol. 1995 Jul;33(1):90-104
references: 7601953
references: Gastroenterology. 2004 Nov;127(5 Suppl 1):S35-50
references: 15508101
references: Liver. 1998 Aug;18(4):272-6
references: 9766824
references: Cancer Res. 1994 Mar 1;54(5):1159-63
references: 8118799
references: Oncogene. 1999 Jan 7;18(1):181-7
references: 9926933
references: Br J Cancer. 2004 Jan 26;90(2):483-91
references: 14735197
references: Fam Cancer. 2007;6(1):141-5
references: 17051350
references: Curr Diagn Pathol. 2007 Aug;13(4):301-319
references: 18670585
references: Gastroenterology. 1999 Jun;116(6):1453-6
references: 10348829
references: Aliment Pharmacol Ther. 2007 Feb 1;25(3):229-45
references: 17217455
references: Clin Genet. 2007 Feb;71(2):130-9
references: 17250661
references: Clin Genet. 2009 Feb;75(2):141-9
references: 19215248
references: Fam Cancer. 2007;6(1):1-12
references: 17039271
references: World J Gastroenterol. 2005 Mar 14;11(10):1481-8
references: 15770724
references: Mod Pathol. 2008 Feb;21(2):159-64
references: 18065960
references: Br J Surg. 1967 Mar;54(3):191-5
references: 6020987
references: Carcinogenesis. 2004 Apr;25(4):541-7
references: 14656944
references: Hepatol Res. 2009 Mar;39(3):266-73
references: 19054153
references: Cancer. 2000 Mar 1;88(5):1025-9
references: 10699890
references: Am J Transplant. 2007 Feb;7(2):476-9
references: 17229076
references: Arch Dermatol. 1968 Nov;98(5):549-51
references: 5684233
references: Cancer Res. 1993 Nov 1;53(21):5087-9
references: 8221640
references: Gut. 1997 Dec;41(6):845-50
references: 9462221
references: J Am Acad Dermatol. 1999 Nov;41(5 Pt 1):681-6
references: 10534628