title: Fluorinated copolymer nanoparticles for multimodal imaging applications.
abstract: Nanomaterials have emerged as valuable tools in biomedical imaging techniques. Here, the synthesis and characterization of a novel fluorinated nanoparticle with potential applications as an MRI contrast agent is reported. Particles were synthesized using a free radical polymerization technique. Secondary ion mass spectrometry analysis showed that the particles' surface contained fluorinated groups and nitrogen-containing groups. Solid-state NMR spectroscopy suggested the presence of two distinct fluorine resonances, which conforms to the structure of the fluorinated monomer. Ongoing studies aim to evaluate the performance of the nanoparticles as MRI contrast agents both in vitro and in vivo.
authors: Department of Chemical and Petroleum Engineering, University of Kansas, Lawrence, Kansas 66047, USA; National Institute of Standards and Technology, 100 Bureau Drive, Mail Stop 8371, Gaithersburg, Maryland 20899, USA.
authors: Mark M
authors: MM
authors: Bailey
authors: Christine M
authors: CM
authors: Mahoney
authors: Kassibla E
authors: KE
authors: Dempah
authors: Jeffrey M
authors: JM
authors: Davis
authors: Matthew L
authors: ML
authors: Becker
authors: Supang
authors: S
authors: Khondee
authors: Eric J
authors: EJ
authors: Munson
authors: Cory
authors: C
authors: Berkland