title: Naevus anaemicus-like hypopigmented macules in dyskeratosis congenita.
abstract: In the present paper we report on a Taiwanese case of X-linked recessive dyskeratosis congenita (DC), confirmed by detection of a 214 C→T mutation in the DKC1 gene, and provide a detailed description of mottled pigmentary changes of the skin, specifically numerous small, whitish macules dispersed against a background of diffuse, finely reticulated hyperpigmentation. The hypopigmented macules showed no discernible erythema upon rubbing or the local application of heat. The naevus anaemicus-like macules may be a relatively common but under-recognized feature in DC. More studies are required to determine the incidence and histopathology of these macules.
authors: Department of Dermatology, National Cheng Kung University, College of Medicine and Hospital, Tainan, Taiwan.
authors: Yi-Pei
authors: YP
authors: Lee
authors: Sheau-Chiou
authors: SC
authors: Chao
authors: Julia Yu-Yun
authors: JY
authors: Lee