title: Comparison of metabolite profiles in U87 glioma cells and mesenchymal stem cells.
abstract: Gas chromatography-mass spectrometry (GC-MS) profiles were generated from U87 glioma cells and human mesenchymal stem cells (hMSC). 37 metabolites representing glycolysis intermediates, TCA cycle metabolites, amino acids and lipids were selected for a detailed analysis. The concentrations of these metabolites were compared and Pearson correlation coefficients were used to calculate the relationship between pairs of metabolites. Metabolite profiles and correlation patterns differ significantly between the two cell lines. These profiles can be considered as a signature of the underlying biochemical system and provide snap-shots of the metabolism in mesenchymal stem cells and tumor cells.
authors: AG Bioinformatics, Institute for Biochemistry and Biology, University of Potsdam, Germany. juerchott@mpimp-golm.mpg.de
authors: Kathrin
authors: K
authors: Jürchott
authors: Ke-Tai
authors: KT
authors: Guo
authors: Gareth
authors: G
authors: Catchpole
authors: Kristen
authors: K
authors: Feher
authors: Lothar
authors: L
authors: Willmitzer
authors: Christian
authors: C
authors: Schichor
authors: Joachim
authors: J
authors: Selbig