title: Decreased thyroid function in Korean women with bipolar disorder receiving valproic acid.
abstract: We report here two adult female patients with bipolar disorder who developed abnormal thyroid function after short-or long-term administration of valproic acid (VPA). The first patient developed sick euthyroid syndrome (relative to her pretreatment thyroid levels) after only 2 months of treatment with VPA and quetiapine. The second patient, who had no pretreatment medical history including thyroid disease, developed hypothyroidism after several years of treatment with VPA and quetiapine.
authors: Department of Neuropsychiatry, Ilsanpaik Hospital, Inje University College of Medicine, Goyang 411-706, South Korea. medipark@hanmail.net
authors: Young-Min
authors: YM
authors: Park
authors: Seung-Gul
authors: SG
authors: Kang
authors: Bun-Hee
authors: BH
authors: Lee
authors: Heon-Jeong
authors: HJ
authors: Lee