title: Problem-solving test: Targeted gene disruption.
abstract: Terms to be familiar with before you start to solve the test: mutation, vector, plasmid, origin of replication, promoter, introns/exons, open reading frame, transfection, circular and linear DNA, DNA integration, homologous recombination, DNA replication, gene expression, heterozygote, homozygote.
authors: Department of Medical Biology, Medical School, University of Pécs, H-7624 Pécs, Hungary. jozsef.szeberenyi@aok.pte.hu.
authors: József
authors: J
authors: Szeberényi