title: Natural killer cells in psoriasis.
abstract: Psoriasis is one of the most common immune-mediated disorders. There is evidence that it is mediated by Th1 and, more recently, Th17 cells. The cytokine pattern, particularly the dominance of TNF-α, implicates the innate immune system in psoriasis pathogenesis. Of the many components of the innate immune system known to be involved in psoriatic lesions, natural killer and natural killer T cells appear to have a unique role. We review the evidence supporting a role for natural killer cells in psoriasis.
authors: Department of Dermatology, St Vincent's University Hospital, Dublin, Ireland. tobin.annemarie@gmail.com
authors: A M
authors: AM
authors: Tobin
authors: L
authors: L
authors: Lynch
authors: B
authors: B
authors: Kirby
authors: C
authors: C
authors: O'Farrelly