title: A national series of 244 sinonasal cancers in Finland in 1990-2004.
abstract: Sinonasal cancer is still a somewhat controversial entity because most series are single-center studies. The aim of this study was to give more accurate and generalisable information about treatment of the neck and prognosis of sinonasal cancer. Retrospective, population-based, multicentre study. Altogether 244 patients diagnosed in 1990-2004 were evaluated. The 3- and 5-year disease-specific survival (DSS) rates after treatment with curative intent were 68 and 57%, respectively. Regional status at the time of the diagnosis (P < 0.001, log rank) and local recurrence (P = 0.02, log rank) during the follow-up had a statistically significant effect on DSS. Initially 13% of the patients were diagnosed with neck metastasis. The proportion of regional recurrences during the follow-up was 9%, but it did not have a statistically significant impact on DSS (P = 0.68, log rank). Histopathology had no statistically significant impact on survival in this material of 244 patients. In conclusion, routine elective neck treatment of all sinonasal cancer patients is not recommended, but the importance of the treatment of the primary location is emphasised.
authors: Department of Otorhinolaryngology-Head and Neck Surgery, Oulu University Hospital, Oulu, Finland.
authors: Petri
authors: P
authors: Koivunen
authors: Antti A
authors: AA
authors: Mäkitie
authors: Leif
authors: L
authors: Bäck
authors: Matti
authors: M
authors: Pukkila
authors: Jussi
authors: J
authors: Laranne
authors: Ilpo
authors: I
authors: Kinnunen
authors: Kalle
authors: K
authors: Aitasalo
authors: Reidar
authors: R
authors: Grénman
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