title: Reference ranges for serum S100B protein during the first three years of life.
abstract: OBJECTIVE
  Clinical and diagnostic management of traumatic brain injuries is problematic in young children. To facilitate this management, we describe blood reference ranges for the well established biomarker S100B in children younger than 3 years.
  
  
  METHODS
  Serum S100B concentrations were determined by electro-chemiluminescence immunoassay in a population of 186 healthy children aged 0-3 years.
  
  
  RESULTS
  Four age groups emerged, i.e. 0-3, 4-9, 10-24 and 25-36 months. We also found an interesting inverse correlation with head circumference.
  
  
  CONCLUSIONS
  This study provides useful serum S100B values from the largest cohort of healthy children aged 0-3 years old.
authors: Clermont-Ferrand Teaching Hospital, Biochemistry Department, Clermont-Ferrand, France.
authors: Damien
authors: D
authors: Bouvier
authors: Christoph
authors: C
authors: Castellani
authors: Mathilde
authors: M
authors: Fournier
authors: Jean-Benoït
authors: JB
authors: Dauphin
authors: Sylvie
authors: S
authors: Ughetto
authors: Mathias
authors: M
authors: Breton
authors: André
authors: A
authors: Labbé
authors: Annelie-Martina
authors: AM
authors: Weinberg
authors: Vincent
authors: V
authors: Sapin