title: Vaginal recurrence more than 17 years after hysterectomy and adjuvant treatment for uterine carcinoma with successful salvage brachytherapy: a case report.
abstract: OBJECTIVE
  Although the majority of recurrences occur within the first 3 years of hysterectomy for endometrioid carcinoma, we report herein a successful salvage vaginal brachytherapy in a patient with endometrioid uterine carcinoma which recurred more than 17 years after initial treatment.
  
  
  METHODS
  A 61-year-old female was diagnosed with endometrioid adenocarcinoma of the uterus and treated with TAH-BSO, followed by adjuvant external beam radiation therapy (EBRT) to the whole pelvis. After remaining free of any recurrent or metastatic disease for more than 17 years, she was diagnosed with isolated vaginal cuff recurrence and successfully treated with a salvage high-dose-rate intracavitary vaginal brachytherapy.
  
  
  RESULTS
  The patient remained disease free until her death from unrelated causes 7 years later.
  
  
  CONCLUSIONS
  To the best of our knowledge, this case represents the longest time to recurrence of endometrial cancer in someone who had been treated with TAH-BSO and adjuvant pelvic EBRT. This case highlights that even with adjuvant therapy, late recurrences may occur, and successful salvage brachytherapy is very effective.
authors: Department of Radiation Oncology, Henry Ford Health System, Detroit, Mich., USA.
authors: Raphael
authors: R
authors: Yechieli
authors: Jared R
authors: JR
authors: Robbins
authors: Daniel
authors: D
authors: Schultz
authors: Adnan
authors: A
authors: Munkarah
authors: Mohamed A
authors: MA
authors: Elshaikh
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