title: Left ventricular assist device support with a centrifugal pump for 2 months in a 5-kg child.
abstract: The mid-term and long-term results of left ventricular assist device (LVAD) implantation for small children are still unsatisfactory. There have been few reports of LVAD implantation for more than a month in children weighing under 5 kg. We report the case of a 4-month-old female infant who survived for 2 months after being diagnosed with dilated cardiomyopathy (DCM) with extracorporeal centrifugal pump support. In recent years, although pumps designed for small children have been introduced and are used as a bridge to transplantation or recovery, mid-term or long-term mechanical support for small children with heart failure is still difficult. We managed to successfully provide support for a low-body-weight child with a centrifugal pump over a mid-term period. We achieved acceptable control of thrombosis, but eventually the infant died of sepsis. Autopsy revealed no prominent thrombosis in the perfusion cannula, drainage cannula, the pump, or the left ventricle. This is the first case report of LVAD support with the centrifugal pump, ROTAFLOW(®) (Maquet, Rastatt, Germany), for 2 months in a child weighing under 5 kg. Our method may potentially save severe heart failure children who need mid-term LVAD support.
authors: Department of Cardiothoracic Surgery, The University of Tokyo, 7-3-1, Hongo, Bunkyo-ku, Tokyo, Japan. takainoue-tky@umin.ac.jp
authors: Takafumi
authors: T
authors: Inoue
authors: Takashi
authors: T
authors: Nishimura
authors: Arata
authors: A
authors: Murakami
authors: Keiichi
authors: K
authors: Itatani
authors: Tetsuhiro
authors: T
authors: Takaoka
authors: Kazuo
authors: K
authors: Kitahori
authors: Akihide
authors: A
authors: Umeki
authors: Toshiko
authors: T
authors: Takezoe
authors: Koichi
authors: K
authors: Kashiwa
authors: Shunei
authors: S
authors: Kyo
authors: Minoru
authors: M
authors: Ono
references: N Engl J Med. 2001 Nov 15;345(20):1435-43
references: 11794191
references: ASAIO J. 2005 Jul-Aug;51(4):452-5
references: 16156312
references: J Heart Lung Transplant. 2006 Jan;25(1):16-21
references: 16399525
references: Clin Infect Dis. 2005 Apr 15;40(8):1108-15
references: 15791509
references: Artif Organs. 2010 Nov;34(11):885-90
references: 20636444
references: Ann Thorac Surg. 2006 Sep;82(3):926-32
references: 16928510
references: Ann Thorac Surg. 2010 Jul;90(1):58-62
references: 20609748
references: ASAIO J. 2010 Jul-Aug;56(4):364-8
references: 20559133
references: J Heart Lung Transplant. 2003 Jul;22(7):770-7
references: 12873545
references: Gen Thorac Cardiovasc Surg. 2008 Jul;56(7):357-60
references: 18607686
references: Pediatr Cardiol. 2005 Jan-Feb;26(1):2-28
references: 15156301