title: (2R,4R)-1-(tert-But-oxy-carbon-yl)-4-meth-oxy-pyrrolidine-2-carb-oxy-lic acid.
abstract: In the title compound, C(11)H(19)NO(5), the five-membered pyrrolidine ring adopts an envelope conformation. The dihedral angles between the carboxyl group plane, the pyrrolidine ring and the meth-oxy group are 59.50 (3) and 62.02 (1)°, respectively. In the crystal, inter-molecular O-H⋯O hydrogen bonds link the mol-ecules into chains along [100]. The absolute configuration is assigned in accord with that of (2R,4R)-1-(tert-but-oxy-carbon-yl)-4-hy-droxy-pyrrolidine-2-carb-oxy-lic acid, which was the starting material in the synthesis.
authors: Jing
authors: J
authors: Yuan
authors: Zhi-Qiang
authors: ZQ
authors: Cai
authors: Chang-Jiang
authors: CJ
authors: Huang
authors: Wei-Ren
authors: WR
authors: Xu
references: Chem Biol Drug Des. 2007 Aug;70(2):100-12
references: 17683371
references: Acta Crystallogr A. 2008 Jan;64(Pt 1):112-22
references: 18156677
references: Hamostaseologie. 2009 Aug;29(3):260-7
references: 19644596