title: Chromium-mediated stereoselective synthesis of carbohydrate-derived (E)-α,β-unsaturated esters or amides.
abstract: A chromium-mediated novel synthesis of carbohydrate-derived di- and trisubstituted (E)-α,β-unsaturated esters or amides from a range of dichloroesters or amides and a variety of sugar aldehydes is reported. The process took place with total stereoselectivity and in high yields. A mechanism based on a sequential chromium-promoted aldol-type reaction and a completely stereoselective β-elimination reaction is proposed to explain these results.
authors: Departamento de Química Orgánica e Inorgánica, Facultad de Química, Universidad de Oviedo, Julián Clavería 8, 33071 Oviedo, Spain.
authors: Humberto
authors: H
authors: Rodríguez-Solla
authors: Carmen
authors: C
authors: Concellón
authors: Elena G
authors: EG
authors: Blanco
authors: Juan Ignacio
authors: JI
authors: Sarmiento
authors: Pamela
authors: P
authors: Díaz
authors: Raquel G
authors: RG
authors: Soengas