title: Necrotic ulcerative changes in Fanconi's anaemia: a case report.
abstract: CONCLUSIONS
  This case report is of a rare occurrence of necrotic ulcerative changes in a female patient with Fanconi's anaemia and its successful periodontal management.
  
  
  BACKGROUND
  The response of the periodontium to certain genetic and haematological disorders may vary from bleeding, ulcerations and necrosis to a more severe form of periodontitis. Periodontal management in such conditions still remains an enigma with respect to the timing of the periodontal intervention with regard to the systemic wellbeing of the patient.
  
  
  METHODS
  Necrotising ulcerative lesions in a patient with Fanconi's anaemia (FA) progressed rapidly in a week's time necessitating early preliminary periodontal care, which included scaling and root planning using ultrasonic equipment supplemented with hydrogen peroxide irrigation, in conjunction with systemic antibiotics and blood transfusion.
  
  
  RESULTS
  Following 1 unit (500ml) of fresh whole blood transfusion 24 hours preoperatively, basic periodontal therapy, comprising of removal of necrotic slough and thorough scaling was done. There was marked resolution of the necrotic ulceration and related symptoms when the patient was followed up for a period of 1 month.
  
  
  CONCLUSIONS
  This report reconfirms most oral manifestations of Fanconi's anaemia and is the first of its kind to associate necrotic ulcerative changes of the gingiva with FA. It also goes a step further to emphasise the clinical significance of multidisciplinary approach towards successful patient management, which was the primary objective.
authors: Department of Peridontics, Bangalore Institute of Dental Sciences, Bangalore, India. drshreyak@rediffmail.com
authors: Sridharan
authors: S
authors: Srirangarajan
authors: Shreya
authors: S
authors: Shetty
authors: Deepak
authors: D
authors: Prasanna