title: Data mining using the Catalogue of Somatic Mutations in Cancer BioMart.
abstract: Catalogue of Somatic Mutations in Cancer (COSMIC) (http://www.sanger.ac.uk/cosmic) is a publicly available resource providing information on somatic mutations implicated in human cancer. Release v51 (January 2011) includes data from just over 19,000 genes, 161,787 coding mutations and 5573 gene fusions, described in more than 577,000 tumour samples. COSMICMart (COSMIC BioMart) provides a flexible way to mine these data and combine somatic mutations with other biological relevant data sets. This article describes the data available in COSMIC along with examples of how to successfully mine and integrate data sets using COSMICMart. DATABASE URL: http://www.sanger.ac.uk/genetics/CGP/cosmic/biomart/martview/.
authors: Cancer Genome Project, The Wellcome Trust Sanger Institute, Hinxton, Cambridgeshire, UK.
authors: Rebecca
authors: R
authors: Shepherd
authors: Simon A
authors: SA
authors: Forbes
authors: David
authors: D
authors: Beare
authors: S
authors: S
authors: Bamford
authors: Charlotte G
authors: CG
authors: Cole
authors: Sari
authors: S
authors: Ward
authors: Nidhi
authors: N
authors: Bindal
authors: Prasad
authors: P
authors: Gunasekaran
authors: Mingming
authors: M
authors: Jia
authors: Chai Yin
authors: CY
authors: Kok
authors: Kenric
authors: K
authors: Leung
authors: Andrew
authors: A
authors: Menzies
authors: Adam P
authors: AP
authors: Butler
authors: Jon W
authors: JW
authors: Teague
authors: Peter J
authors: PJ
authors: Campbell
authors: Michael R
authors: MR
authors: Stratton
authors: P Andrew
authors: PA
authors: Futreal
references: Curr Protoc Hum Genet. 2008 Apr;Chapter 10:Unit 10.11
references: 18428421
references: Science. 2008 Sep 26;321(5897):1807-12
references: 18772396
references: Methods Mol Biol. 2011;696:93-105
references: 21063943
references: Nature. 2010 Apr 15;464(7291):993-8
references: 20393554
references: Nucleic Acids Res. 2009 Jul;37(Web Server issue):W23-7
references: 19420058
references: Nucleic Acids Res. 2010 Jan;38(Database issue):D557-62
references: 19906699
references: Hum Mutat. 2007 Jun;28(6):622-9
references: 17311302
references: Nat Rev Cancer. 2010 Apr;10(4):241-53
references: 20300105
references: Genome Res. 2002 Oct;12(10):1599-610
references: 12368253
references: Nat Rev Drug Discov. 2009 Sep;8(9):709-23
references: 19629074
references: Hum Mutat. 2000;15(1):7-12
references: 10612815
references: Nucleic Acids Res. 2009 Jan;37(Database issue):D211-5
references: 18940856
references: Science. 2006 Oct 13;314(5797):268-74
references: 16959974
references: Nucleic Acids Res. 2010 Jan;38(Database issue):D652-7
references: 19906727
references: Methods Enzymol. 2008;438:331-41
references: 18413259
references: Nature. 2008 Oct 23;455(7216):1069-75
references: 18948947
references: Nucleic Acids Res. 2011 Jan;39(Database issue):D691-7
references: 21067998