title: 3D analysis of spontaneous upbeat nystagmus in a patient with astrocytoma in cerebellum.
abstract: OBJECTIVE
  We report the case of a 58-year-old female patient who consulted our Department complaining of positional vertigo and showing spontaneous upbeat nystagmus (UBN) in darkness.
  
  
  METHODS
  We analyzed her UBN three-dimensionally. The MRI scan revealed the astrocytoma in the left cerebellum involving the cerebellar vermis.
  
  
  RESULTS
  Three-dimensional analysis showed a spontaneous UBN rotating around the intra-aural axis in the pitch plane.
  
  
  CONCLUSIONS
  Since the cerebellar vermis is known to plays an inhibitory role on the central vertical vestibule-ocular reflex (VOR), the present results suggest that the spontaneous UBN in darkness observed in this patient was induced by an imbalance of central vertical VOR tone.
authors: Depatrment of Otorhinolaryngology--Head and Neck Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suitashi, Osaka, Japan.
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