title: Isoflavone dimers and other bioactive constituents from the figs of Ficus mucuso.
abstract: Phytochemical investigation of the figs of Ficus mucuso led to the isolation of three new isoflavone dimer derivatives, mucusisoflavones A-C (1-3), together with 16 known compounds. Some of the isolates were tested in vitro for their inhibitory properties toward β-glucuronidase and Plasmodium falciparum enoyl-ACP reductase (PfENR) enzymes. Compound 1 (IC₅₀) 0.68 μM) showed inhibitory activity on β-glucuronidase enzyme, while 3 (IC₅₀) 7.69 μM) exhibited a weak inhibitory activity against P. falciparum enoyl-ACP reductase (PfENR).
authors: Department of Organic Chemistry, Faculty of Science, TWAS Research Unit of the University of Yaoundé I , P.O. Box 812, Yaoundé, Cameroon.
authors: Jean J K
authors: JJ
authors: Bankeu
authors: Rustamova
authors: R
authors: Khayala
authors: Bruno N
authors: BN
authors: Lenta
authors: Didérot T
authors: DT
authors: Noungoué
authors: Silvère A
authors: SA
authors: Ngouela
authors: Sufyan A
authors: SA
authors: Mustafa
authors: Khalid
authors: K
authors: Asaad
authors: Mohammed I
authors: MI
authors: Choudhary
authors: Sean T
authors: ST
authors: Prigge
authors: Ralphreed
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authors: Hasanov
authors: Augustin E
authors: AE
authors: Nkengfack
authors: Etienne
authors: E
authors: Tsamo
authors: Muhammad S
authors: MS
authors: Ali