title: Palladium-catalyzed synthesis of indoles via ammonia cross-coupling-alkyne cyclization.
abstract: The synthesis of indoles via the metal-catalyzed cross-coupling of ammonia is reported for the first time; the developed protocol also allows for the unprecedented use of methylamine or hydrazine as coupling partners. These Pd/Josiphos-catalyzed reactions proceed under relatively mild conditions for a range of 2-alkynylbromoarenes.
authors: Department of Chemistry, Dalhousie University, Halifax, Nova Scotia, B3H 4J3, Canada.
authors: Pamela G
authors: PG
authors: Alsabeh
authors: Rylan J
authors: RJ
authors: Lundgren
authors: Lauren E
authors: LE
authors: Longobardi
authors: Mark
authors: M
authors: Stradiotto