title: Transfusion-Related Acute Lung Injury (TRALI): Report of 2 Cases and a Review of The Literature.
abstract: Transfusion of allogeneic blood products is given for correction of coagulation deficits and for the improvement in oxygen-carrying capacity or delivery. Blood transfusion has become safer following the advancement in blood testing using state-of-the-art viral assays; however, there continues to exist a variety of noninfectious transfusion risks that still remain and that cannot be entirely eliminated. Research is now directed towards understanding these lesser-known, but serious transfusion-related complications. This purpose of this review is to discuss a serious noninfectious cause of acute lung injury, transfusion-related acute lung injury (TRALI), which occurred in 2 recent cases in the intensive care unit, and to review the current literature of this syndrome.
authors: Department of Anesthesiology, Ochsner Clinic Foundation, New Orleans, LA.
authors: Bobby D
authors: BD
authors: Nossaman
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