title: Inflammatory markers: exhaled nitric oxide and carbon monoxide during the ovarian cycle.
abstract: Nitric oxide (NO) production and carbon monoxide (CO) production are increased in inflammatory lung diseases. Although there are some pieces of evidence for hormonal modulation by estrogen, little is known about exhaled NO and CO during the ovarian cycle. In 23 subjects, we measured exhaled NO and CO by an online analyzer. Significantly higher levels of exhaled NO were found at the midcycle compared with those in the premenstrual period or during menstruation. Higher levels of CO were after ovulation and reached a peak in the premenstrual phase. The lowest levels of CO were observed in the first days of the estrogen phase. In males, there was no significant variation in exhaled NO and CO. Exhaled NO and CO levels vary during the ovarian cycle in women, and this fact should be taken into account during serial measurements of these markers in the female population.
authors: Department of Pneumology and Allergy, Medical University of Lodz, Kopcińskiego 22, 90-153 Łódź, Poland.
authors: Adam
authors: A
authors: Antczak
authors: Maciej
authors: M
authors: Ciebiada
authors: Sergei A
authors: SA
authors: Kharitonov
authors: Pawel
authors: P
authors: Gorski
authors: Peter J
authors: PJ
authors: Barnes
references: Eur Respir J. 2008 Mar;31(3):539-46
references: 18057062
references: J Appl Physiol (1985). 1989 Aug;67(2):517-22
references: 2507498
references: Am J Respir Crit Care Med. 2005 Apr 15;171(8):912-30
references: 15817806
references: Acta Med Scand. 1975 Sep;198(3):155-60
references: 1180125
references: Cancer Res. 1991 Feb 1;51(3):974-8
references: 1988141
references: Am J Respir Crit Care Med. 2000 Mar;161(3 Pt 1):694-9
references: 10712309
references: Am J Physiol. 1997 Nov;273(5):L980-8
references: 9374724
references: Pediatr Hematol Oncol. 2010 Mar;27(2):112-21
references: 20201692
references: J Clin Invest. 1995 Dec;96(6):2676-82
references: 8675634
references: Am J Respir Cell Mol Biol. 1999 Apr;20(4):658-66
references: 10100997
references: J Appl Physiol (1985). 1992 Aug;73(2):393-404
references: 1399957
references: J Biol Chem. 1995 Mar 17;270(11):5710-3
references: 7890697
references: Am J Respir Crit Care Med. 1996 Jan;153(1):454-7
references: 8542158
references: Chest. 1999 Oct;116(4):1007-11
references: 10531166
references: Hepatology. 2003 Aug;38(2):452-9
references: 12883490
references: Thorax. 1999 Oct;54(10):917-20
references: 10491455
references: Curr Opin Otolaryngol Head Neck Surg. 2007 Aug;15(4):258-63
references: 17620900
references: Br Heart J. 1994 Sep;72(3):243-5
references: 7946774
references: Thorax. 1998 Aug;53(8):668-72
references: 9828853
references: Annu Rev Pharmacol Toxicol. 1997;37:517-54
references: 9131263
references: J Biol Chem. 1997 Feb 14;272(7):4295-301
references: 9020147
references: J Clin Invest. 1998 Mar 1;101(5):949-55
references: 9486963
references: Annu Rev Pharmacol Toxicol. 1990;30:535-60
references: 2188578
references: Respir Med. 2009 May;103(5):700-6
references: 19117740
references: Biomarkers. 2002 Jan-Feb;7(1):1-32
references: 12101782
references: Am J Respir Cell Mol Biol. 1996 Jul;15(1):9-19
references: 8679227
references: Respir Med. 2001 Feb;95(2):153-8
references: 11217912
references: Chest. 2005 Nov;128(5):3316-21
references: 16304278
references: Am J Physiol. 1996 Jan;270(1 Pt 2):H107-14
references: 8769740
references: Clin Exp Allergy. 2002 Feb;32(2):224-7
references: 11929486
references: Am J Respir Crit Care Med. 1996 Jun;153(6 Pt 1):1773-80
references: 8665033
references: Chest. 1999 May;115(5):1352-6
references: 10334152
references: Thorax. 1998 Oct;53(10):867-70
references: 10193374
references: Gut. 1994 Nov;35(11):1543-6
references: 7828969
references: Pediatr Pulmonol. 2006 May;41(5):470-4
references: 16547965
references: J Allergy Clin Immunol. 1986 Jan;77(1 Pt 1):87-94
references: 3944377
references: Physiol Rev. 2006 Apr;86(2):583-650
references: 16601269
references: J Pathol. 1998 Mar;184(3):323-31
references: 9614386
references: Chest. 1994 Jul;106(1):318-9
references: 8020306