title: Prevalence and determinants of pre-term deliveries in the University of Ilorin Teaching Hospital, Ilorin, Nigeria.
abstract: In Nigeria, over 900,000 children under the age of five years die every year. Early neonatal death is responsible for a little over 20% of these deaths. Prematurity remains a significant cause of these early neonatal deaths. In some series, it is reported to be responsible for 60-70% of these deaths. This study aimed to determine the prevalence and determinants of pre-term deliveries at the University of Ilorin Teaching Hospital, Ilorin. This was a prospective cohort study conducted over a 9-month period at the University of Ilorin Teaching Hospital. Records of deliveries and data on maternal socio-biological and antenatal variables were collected during this period in order to determine the prevalence and determinants of pre-term deliveries. Out of the 2,489 deliveries that took place over a 9-month period, there were 293 pre-terms, giving a pre-term delivery rate of 120 per 1,000 deliveries. Of the total deliveries, 1,522 singleton deliveries that satisfied inclusion criteria were recruited; 185 of them were pre-term deliveries giving a case:control ratio of 1:7. Significant determinants of pre-term delivery identified were previous pre-term delivery (P=0.001; OR=3.55; 95% CI=1.71-7.30), antepartum hemorrhage (P=0.000; OR=8.95; 95%CI=4.06-19.78), premature rupture of the membranes (P=0.000; OR=6.48; 95%CI=4.33-9.67), maternal urinary tract infection (P=0.006; OR=5.89; 95%CI=1.16-27.57), pregnancy induced hypertension (P=0.007; OR=3.23; 95%CI=2.09-4.99), type of labor (P=0.000; OR=6.44; 95%CI=4.42-9.38) and booking status (P=0.000; OR=4.67; 95%CI=3.33-6.56). The prevalence of pre-term delivery was 120 per 1,000 live births. Factors significantly associated with pre-term delivery were low socio-economic class, previous pre-term delivery, antepartum hemorrhage, premature rupture of fetal membranes, urinary tract infection, pregnancy induced hypertension, induced labor, and booking elsewhere outside the teaching hospital.
authors: Neonatal Intensive Care Unit, Department of Paediatrics, University of Ilorin Teaching Hospital, Ilorin, Nigeria;
authors: Olugbenga A
authors: OA
authors: Mokuolu
authors: Bm
authors: B
authors: Suleiman
authors: Oo
authors: O
authors: Adesiyun
authors: A
authors: A
authors: Adeniyi
references: Hum Reprod. 2005 Nov;20(11):3235-7
references: 16037105
references: Early Pregnancy (Cherry Hill). 2001 Jan;5(1):49-50
references: 11753511
references: BMJ. 1999 Apr 17;318(7190):1059-62
references: 10205109
references: Am J Obstet Gynecol. 1989 Sep;161(3):817-24
references: 2675611
references: Am J Epidemiol. 1995 Dec 1;142(11):1184-93
references: 7485065
references: Int J Gynaecol Obstet. 1991 Sep;36(1):23-7
references: 1683297
references: Public Health. 2005 Feb;119(2):77-86
references: 15694954
references: Br J Obstet Gynaecol. 1996 Aug;103(8):800-5
references: 8760711
references: J Pediatr. 1979 Nov;95(5 Pt 1):769-74
references: 490248
references: West Afr J Med. 1993 Oct-Dec;12(4):228-30
references: 8199066
references: Am J Epidemiol. 2001 Aug 15;154(4):307-15
references: 11495853
references: Lancet. 1984 Mar 10;1(8376):553-5
references: 6142262
references: Rev Epidemiol Sante Publique. 1995;43(3):215-24
references: 7784671
references: J Trop Pediatr. 1994 Apr;40(2):78-81
references: 8015035
references: J Trop Med Hyg. 1995 Jun;98(3):155-60
references: 7783271
references: Am J Obstet Gynecol. 2006 Dec;195(6):1557-63
references: 17014813
references: BJOG. 2005 Mar;112 Suppl 1:1-3
references: 15715585
references: Semin Perinatol. 1988 Oct;12(4):262-79
references: 3065940
references: Neuro Endocrinol Lett. 2004 Dec;25 Suppl 1:43-7
references: 15735585
references: Acta Obstet Gynecol Scand. 2005 Jun;84(6):558-65
references: 15901267
references: Paediatr Perinat Epidemiol. 2004 Mar;18(2):154-63
references: 14996257
references: Trop Doct. 2004 Jul;34(3):165-8
references: 15267050
references: Pediatrics. 2006 Jan;117(1):168-83
references: 16396875
references: JAMA. 1982 Mar 19;247(11):1585-8
references: 7062461
references: N Engl J Med. 1993 Nov 25;329(22):1597-601
references: 8179651
references: Semin Perinatol. 2001 Oct;25(5):348-59
references: 11707021
references: J Clin Epidemiol. 1996 Apr;49(4):441-8
references: 8621995
references: Indian Pediatr. 2003 Oct;40(10):991-5
references: 14581739
references: East Afr Med J. 1984 Jun;61(6):461-9
references: 6545187