title: Orthogonal projection approach applied to peak purity assessment.
abstract: The orthogonal projection approach (OPA), a stepwise approach based on an orthogonalization algorithm, is proposed. The performance of OPA for the assessment of peak purity in HPLC-DAD is described and compared with that of SIMPLISMA. The occurrence of artifacts in both approaches under nonideal situations is discussed.
authors: ChemoAC, Vrije Universiteit Brussel, Laarbeeklaan 103, B-1090 Brussels, Belgium.
authors: F C
authors: FC
authors: Sánchez
authors: J
authors: J
authors: Toft
authors: B
authors: B
authors: van den Bogaert
authors: D L
authors: DL
authors: Massart