title: The expression of E-cadherin as a prognostic factor in breast cancer.
abstract: We examined the clinical significance of E-cadherin expression in 98 patients with breast cancer. E-cadherin expression significantly correlated with histologic grade (p=0.0323) and tended to correlate with the absence of axillary lymph node metastases (p=0.0646). The expression of E-cadherin was associated significantly with the recurrence rate (p=0.0334) and marginally associated with disease-free (p=0.0597) but not overall survival, in univariate analysis. The association between E-cadherin expression and disease-free survival was lost in multivariate analysis. The prognostic value of E-cadherin expression in breast cancer appears to be limited. A larger, prospective study with long-term follow-up is needed.
authors: KANAZAWA UNIV HOSP,SCH MED,OPERAT CTR,KANAZAWA,ISHIKAWA 920,JAPAN. KANAZAWA UNIV HOSP,SCH MED,DEPT SURG 2,KANAZAWA,ISHIKAWA 920,JAPAN.
authors: F
authors: F
authors: Kawahara
authors: M
authors: M
authors: Noguchi
authors: R
authors: R
authors: Yagasaki
authors: M
authors: M
authors: Minami
authors: M
authors: M
authors: Earashi
authors: K
authors: K
authors: Kinoshita
authors: N
authors: N
authors: Ohta
authors: T
authors: T
authors: Taniya
authors: I
authors: I
authors: Miyazaki