title: Cellular effects of progranulin in health and disease.
abstract: Progranulin is a fascinating multifunctional protein, which has been implicated in cell growth, wound repair, tumorigenesis, inflammation, neurodevelopment, and more recently in neurodegeneration. The mechanism of action of this protein is still largely unknown, but the knowledge about the cellular effects on various cell types is expanding. In the current review, we will summarize what is known about the cell biology of progranulin. A better understanding of the biology of progranulin will impact diverse areas of research.
authors: Vesalius Research Center, VIB, Leuven, Belgium.
authors: Louis
authors: L
authors: De Muynck
authors: Philip
authors: P
authors: Van Damme
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