title: [Demyelinating disease affecting both central and peripheral nervous system].
abstract: BACKGROUND
  Demyelinating disease affecting both the central and the peripheral nervous systems has rarely been reported.
  
  
  METHODS
  A 30-year-old man, presented with ataxia and diffuse areflexia due to polyneuropathy fullfilling demyelination criteria. His medical history was notable for central nervous system demyelination compatible with multiple sclerosis. He improved transiently with intravenous immunoglobulin and then stabilized with methotrexate.
  
  
  CONCLUSIONS
  This case report distinguishes a new kind of inflammatory disease affecting both central and peripheral nervous system. It seems to be different from multiple sclerosis and chronic immune demyelinating polyneuropathy, because of high hyperproteinorachia and absence of oligoclonal bands in the cerebrospinal fluid.
authors: Service de neurologie, CHU de Montpellier, hôpital Gui de Chauliac, 80, avenue Augustin-Flîche, 34295 Montpellier cedex 5, France.
authors: C
authors: C
authors: Carra-Dallière
authors: A
authors: A
authors: Mania
authors: B
authors: B
authors: Carlander
authors: W
authors: W
authors: Camu
authors: R
authors: R
authors: Juntas-Morales