title: (S)-3-Chloro-4-(4-ethyl-piperazin-1-yl)-5-[(1R,2S,5R)-2-isopropyl-5-methyl-cyclo-hex-yloxy]furan-2(5H)-one.
abstract: The title compound, C(20)H(33)ClN(2)O(3), was obtained via a tandem asymmetric Michael addition-elimination reaction of 3,4-dichloro-5-(S)-(l-menth-yloxy)furan-2(5H)-one and 1-ethyl-piperazine in the presence of potassium fluoride. The mol-ecular structure contains an approximately planar five-membered furan-one ring [maximum atomic deviation = 0.024 (2) Å] and two six-membered rings adopting chair conformations. Weak inter-molecular C-H⋯O hydrogen bonding is present in the crystal structure.
authors: School of Chemistry and Environment, South China Normal University, Guangzhou 510006, People's Republic of China.
authors: Jian-Hua
authors: JH
authors: Fu
authors: Zhao-Yang
authors: ZY
authors: Wang
authors: Kai
authors: K
authors: Yang
authors: Chao-Xu
authors: CX
authors: Mao
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