title: Part 1: N-alkylated glycines as potent α2δ ligands.
abstract: A new series of glycine-derived ligands of the α(2)δ subunit of voltage gated calcium channels is described. Several novel compounds (7) based on (6) were prepared that possessed a potency <100 nM in the α(2)δ binding assay.
authors: Sandwich Laboratories, Pfizer Global Research and Development, Sandwich, Kent, UK.
authors: Lisa R
authors: LR
authors: Thompson
authors: David C
authors: DC
authors: Blakemore
authors: Delphine
authors: D
authors: Brugier
authors: Justin S
authors: JS
authors: Bryans
authors: Wai-Lam A
authors: WL
authors: Chu
authors: Graham N
authors: GN
authors: Maw
authors: Cedric
authors: C
authors: Poinsard
authors: David J
authors: DJ
authors: Rawson
authors: Andrew N
authors: AN
authors: Warren