title: Marjolin's ulcer associated with ulceration and chronic osteomyelitis.
abstract: This report describes a 78-year old male patient with a chronic venous ulcer on his left leg for the past 24 years, complicated by a squamous-cell carcinoma. After staging of the disease, the treatment administered was amputation of the leg above the knee. Marjolin's ulcer consists of the malignant transformation of a chronic ulcerative lesion. It is a relatively rare phenomenon. The malignant tumor most commonly described in the literature is squamous cell carcinoma, followed by basal-cell carcinoma, sarcoma and melanoma. The pathogenesis of Marjolin's ulcer remains to be fully clarified.
authors: Hospital de Santarém, Santarém, Portugal.
authors: Ermelindo
authors: E
authors: Tavares
authors: Gonçalo
authors: G
authors: Martinho
authors: José Alberto
authors: JA
authors: Dores
authors: Frederico
authors: F
authors: Vera-Cruz
authors: Luís
authors: L
authors: Ferreira