title: [A case of sarcomatoid carcinoma of the lung successfully treated with carboplatin, paclitaxel and bevacizumab].
abstract: A 63-year-old male smoker with left chest pain was admitted for examination of an abnormal chest shadow. A chest computed tomography (CT) scan revealed a tumor in S6 of the left lung, and left pleural effusion. Histological examination by CT-guided needle biopsy revealed a proliferation of spindle-shaped tumor cells with sarcomatous features. Immunohistochemical staining confirmed the tumor cells to be of epidermal origin, indicating a diagnosis of sarcomatoid carcinoma of the lung. No distant metastases were found, and his disease was judged to be clinical stage IV (T3N2M1a). He received 5 courses of systemic chemotherapy consisting of carboplatin, paclitaxel and bevacizumab, and the tumor shrank. Systemic chemotherapy is generally ineffective for sarcomatoid carcinoma of the lung. However, in the present case this chemotherapy was effective with the addition of bevacizumab.
authors: Department of Thoracic Oncology, National Hospital Organization Toneyama National Hospital.
authors: Teppei
authors: T
authors: Sugano
authors: Masahide
authors: M
authors: Mori
authors: Yoshinobu
authors: Y
authors: Namba
authors: Takeshi
authors: T
authors: Uenami
authors: Shin-ichi
authors: S
authors: Kagami
authors: Soichiro
authors: S
authors: Yokota