title: Spectral-temporal analysis of cortical oscillations during lexical processing.
abstract: We investigated the oscillatory neural correlates of auditory lexical processing in healthy adults. Synthetic aperture magnetometry was used to characterize the timing of event-related desynchronization (ERD)/event-related synchronization (ERS) in superior temporal gyri following low-frequency and high-frequency words in contrast to nonwords. ERS and ERD responses were found with both word and nonword stimuli. Analysis of power revealed significantly elevated θ-α range (6-14 Hz) ERD in response to words compared with nonwords (left hemisphere: 390-945 ms poststimulus). Furthermore, a burst of ERS in the γ band (40-50 Hz, centered at 410 ms poststimulus) distinguished high-frequency and low-frequency words, and also displayed left-hemispheric enhancement following words. Results demonstrate a clear neural correlate of lexical access and provide a basis for further study of spectral-temporal brain activity during language processing.
authors: Lurie Family Foundations' MEG Imaging Center, Department of Radiology, Children's Hospital of Philadelphia, University of Pennsylvania, USA.
authors: Kambiz
authors: K
authors: Tavabi
authors: David
authors: D
authors: Embick
authors: Timothy P L
authors: TP
authors: Roberts