title: Sulfoxide-alkene hybrids: a new class of chiral ligands for the Hayashi-Miyaura reaction.
abstract: Sulfoxide-alkene hybrids are introduced as a new class of chiral heterodentate ligands for the Hayashi-Miyaura reaction. The synthesis of these ligands was achieved without the use of protecting groups. A chiral resolution was performed via simple column-chromatographic separation of the diastereomeric ligands. Both diastereomers proved to be excellent ligands in Rh-catalyzed 1,4-addition reactions, furnishing chiral products with high enantioselectivities and, remarkably, opposite stereoconfigurations.
authors: Department Chemie, Ludwig-Maximilians-Universität München, Butenandtstrasse 5-13, 81377 München, Germany.
authors: Tobias
authors: T
authors: Thaler
authors: Li-Na
authors: LN
authors: Guo
authors: Andreas K
authors: AK
authors: Steib
authors: Mihai
authors: M
authors: Raducan
authors: Konstantin
authors: K
authors: Karaghiosoff
authors: Peter
authors: P
authors: Mayer
authors: Paul
authors: P
authors: Knochel