title: Different characteristics of peripartum cardiomyopathy between patients complicated with and without hypertensive disorders. -Results from the Japanese Nationwide survey of peripartum cardiomyopathy-.
abstract: BACKGROUND
  There has been no nationwide survey concerning peripartum cardiomyopathy (PPCM) among the Asian population, and clinical profiles of PPCM complicated with hypertensive disorders complicating pregnancy (HD) as the major risk factor of PPCM have not been characterized.
  
  
  RESULTS
  A retrospective, nationwide survey of PPCM in 2007 and 2008 all over Japan was performed and the clinical characteristics were compared between patients with and without HD. We obtained data for 102 patients. HD during pregnancy occurred in 42 patients (41%). Patients with HD were older than those without HD (33.8 vs. 31.9 years old, P<0.05) and babies were delivered more frequently by Caesarean section (81% vs. 52%, P<0.01). Although cardiac parameters at diagnosis were similar in patients with and without HD, patients with HD were hospitalized for a shorter period and had better cardiac function after 7 months. Multivariate regression analysis revealed that HD was independently associated with a shorter hospital stay and a higher left ventricular ejection fraction at last follow up.
  
  
  CONCLUSIONS
  PPCM complicated with HD had different clinical characteristics from those without HD. This condition might be a unique subset of PPCM that is characterized by relatively swift recovery except in the cases of death. In order to prevent severe heart failure and maternal death, peripartum women should be treated with HD cautiously and must immediately undergo a cardiac examination as needed.
authors: Department of Perinatology and Gynecology, National Cerebral and Cardiovascular Center, Fuchu, Japan. chiz@hsp.ncvc.go.jp
authors: Chizuko A
authors: CA
authors: Kamiya
authors: Masafumi
authors: M
authors: Kitakaze
authors: Hatsue
authors: H
authors: Ishibashi-Ueda
authors: Satoshi
authors: S
authors: Nakatani
authors: Toyoaki
authors: T
authors: Murohara
authors: Hitonobu
authors: H
authors: Tomoike
authors: Tomoaki
authors: T
authors: Ikeda