title: Ghrelin axis genes, peptides and receptors: recent findings and future challenges.
abstract: The ghrelin axis consists of the gene products of the ghrelin gene (GHRL), and their receptors, including the classical ghrelin receptor GHSR. While it is well-known that the ghrelin gene encodes the 28 amino acid ghrelin peptide hormone, it is now also clear that the locus encodes a range of other bioactive molecules, including novel peptides and non-coding RNAs. For many of these molecules, the physiological functions and cognate receptor(s) remain to be determined. Emerging research techniques, including proteogenomics, are likely to reveal further ghrelin axis-derived molecules. Studies of the role of ghrelin axis genes, peptides and receptors, therefore, promises to be a fruitful area of basic and clinical research in years to come.
authors: Queensland University of Technology, Brisbane, Queensland, Australia.
authors: Inge
authors: I
authors: Seim
authors: Peter
authors: P
authors: Josh
authors: Peter
authors: P
authors: Cunningham
authors: Adrian
authors: A
authors: Herington
authors: Lisa
authors: L
authors: Chopin