title: An unusual case of hypothermia associated with therapeutic doses of olanzapine: a case report.
abstract: BACKGROUND
  We report a case of a 42-year-old man who had symptomatic hypothermia as a result of taking olanzapine for paranoid schizophrenia. According to published data, only a few cases of hypothermia associated with olanzapine have been reported since its introduction into clinical use.
  
  
  METHODS
  A 42-year-old Sri Lankan man with schizophrenia who was being treated with a therapeutic dose of olanzapine presented with reduced level of consciousness. He had a core temperature of 32°C and was bradycardic. At the time of admission, the electrocardiogram showed sinus bradycardia with J waves. He did not have any risk factors for developing hypothermia except the use of olanzapine. There was improvement in his clinical condition with reversal of electrocardiogram changes following gradual rewarming and the omission of olanzapine.
  
  
  CONCLUSIONS
  Hypothermia induced by antipsychotic medications is not uncommon, but olanzapine-induced hypothermia is rare and occurrence has been reported during initiation or increasing the dose. But here the patient developed hypothermia without dose adjustment.
authors: Medical Unit, Teaching Hospital, Kandy, Sri Lanka. lrasnayake@gmail.com.
authors: Lalith Rmr
authors: LR
authors: Rasnayake
authors: Harith
authors: H
authors: Wimalarathne
authors: Runkman Ktdp
authors: RK
authors: Jayapala
authors: Chaminda Dm
authors: CD
authors: Gamage
authors: Dinesh Lb
authors: DL
authors: Dassanayake
authors: Shiroma L
authors: SL
authors: Ratnayake
authors: Anuradha
authors: A
authors: Colombage
authors: Damith
authors: D
authors: Nandadeva
authors: Amitha Npk
authors: AN
authors: Nelumdeniya
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