title: Induction of breast neoplasia and lung granulomas in mice by an antifungal drug (griseofulvin).
abstract: Infiltrating duct carcinomas were induced in the mammary glands of 7 out of 60 experimental female mice force-fed with the antifungal drug griseofulvin, at a daily dose lever of 0.3 mg/30g body weight, for 12 months. The first mammary gland tumor appeared 8 months after the initiation of feeding. Other pathological changes such as bronchocentric granulomas appeared in some male and female treated animals (16.5%).
authors: UNIV ALEXANDRIA,FAC EDUC,DEPT BIOL,ALEXANDRIA,EGYPT. UNIV ALEXANDRIA,FAC MED,DEPT PATHOL,ALEXANDRIA,EGYPT.
authors: M
authors: M
authors: Elmofty
authors: M
authors: M
authors: Shwaireb
authors: A
authors: A
authors: Essawy
authors: A
authors: A
authors: Rizk
authors: H
authors: H
authors: Abdelkerim