title: [Frailty and its association with mortality, hospitalization and functional dependence in Mexicans aged 60-years or older].
abstract: OBJECTIVE
  To determine the association between frailty and mortality, dysfunctionality, falls and hospitalizations in the Mexican Health and Aging Study.
  
  
  METHODS
  Prospective, population study in Mexico, that included subjects of 60 years and older who were evaluated for the variables of frailty during the year 2001 (first wave of the study) which included: difficulty to rise from a chair after being seated during long time, weight loss of 5 kilograms or more in the last two years, and absence of energy. Frail subjects were considered when they had at least two conditions. The robust group was considered when they had zero conditions. Pre-frail or intermediate were those with one condition. Mortality, hospitalizations, falls, and functional dependency were evaluated during 2003 (second wave of the study). Relative risk was calculated for each complication, as well as hazard ratio and odds ratio through Cox Regression Model (for mortality) and logistic regression (for the rest of the complications) respectively, adjusted for covariates.
  
  
  RESULTS
  The states of frailty and pre-frailty were independently associated with mortality, hazard ratio of 1.61 (CI 95% 1.01-2.55) and 1.94 (CI 95% 1.20-3.13), respectively. Only the state of frailty was independently associated with hospitalization and functional dependence, odds ratio of 1.53 (CI 95% 1.13-2.07) and 3.07 (CI 95% 1.76-5.34). There was no association between pre-frailty or frailty with falls.
  
  
  CONCLUSIONS
  Frailty is associated with an increase in the rate of mortality, hospitalizations and dependence in basic activities of daily life.
authors: Departamento de Medicina Interna, Hospital General de Zona No. 67, Instituto Mexicano del Seguro Social, Monterrey, Nuevo León, México.
authors: Enrique
authors: E
authors: Díaz de León González
authors: Héctor Eloy
authors: HE
authors: Tamez Pérez
authors: Hugo
authors: H
authors: Gutiérrez Hermosillo
authors: Javier Armando
authors: JA
authors: Cedillo Rodríguez
authors: Gabriela
authors: G
authors: Torres
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