title: Retention of regiochemistry and chirality in the ruthenium catalyzed allylic alkylation of disubstituted allylic esters.
abstract: The regiospecific nucleophilic substitution during the ruthenium catalyzed allylic alkylation of 1,3-unsymmetrical disubstituted allylic esters was demonstrated. The nucleophile was selectively introduced at the position originally substituted with leaving group in the 2-DPPBA or ip-pybox ligated [RuCl(2)(p-cymene)](2) catalyzed allylic alkylation of 1,3-unsymmetrical disubstituted allylic esters. The chirality of the optically active allylic esters was also transferred to the alkylated products.
authors: Department of Chemistry and Biotechnology, Graduate School of Engineering, Tottori University, Koyama, Tottori 680-8552 Japan. kawatsur@chem.tottori-u.ac.jp
authors: Motoi
authors: M
authors: Kawatsura
authors: Michinobu
authors: M
authors: Sato
authors: Hiroaki
authors: H
authors: Tsuji
authors: Fumio
authors: F
authors: Ata
authors: Toshiyuki
authors: T
authors: Itoh