title: [Pharmacokinetics and pharmacodynamics of antifungal drugs in children].
abstract: The pharmacokinetics and pharmacodynamics of the main antifungal drugs used for invasive fungal infections (amphotéricin B, flucytosine, triazole compounds, echinocandins) have been more or less completely investigated in the paediatric population. This article reviews the pharmacokinetic profiles of these drugs in children, with a focus on the age-related changes. The concentration/efficacy relationships that were evidenced in children are also described.
authors: Université Paris Descartes, Inserm U 663, Service de Pharmacologie Clinique, Hôpital Saint-Vincent de Paul, 74-82, avenue Denfert-Rochereau, 75014 Paris, France. vincent.jullien@svp.aphp.fr
authors: V
authors: V
authors: Jullien