title: [Serum alpha-fetoprotein levels in pregnant women with indeterminate result of anti hepatitis C virus antibodies analysis].
abstract: OBJECTIVE
  Comparison of alpha-fetoprotein (AFP) levels in blood sera samples of women in the early stages of pregnancy with positive or indeterminate results of anti-HCV.
  
  
  METHODS
  Blood sera samples of women in the first trimester of pregnancy were analyzed by using microplate test systems for enzyme immunoassay (EIA) with complex and separate detection of antibodies against hepatitis C virus (HCV) antigens.
  
  
  RESULTS
  AFP levels were higher in women in the first trimester of pregnancy with anti-HCV than in women without anti-HCV. AFP levels in blood sera samples of pregnant women with indeterminate results of anti-HCV analysis were higher than in blood sera samples of pregnant women without anti-HCV. No differences in serum AFP levels were observed between anti-HCV positive samples and samples with indeterminate results of analysis.
  
  
  CONCLUSIONS
  Increased AFP level in the first trimester of pregnancy was observed not only in women with HCV infection, but also in women with indeterminate results of anti-HCV analysis. The data suggest that these groups may have epidemiological similarity.
authors: A A
authors: AA
authors: Potapova
authors: L V
authors: LV
authors: Koval'chuk