title: Cultivation of the first mesophilic representative ("mesotoga") within the order Thermotogales.
abstract: Cultivated members of the order Thermotogales comprise only thermophilic to hyperthermophilic anaerobic microorganisms. However, based on molecular studies, the existence of mesophilic members ("mesotoga") within this order has been postulated but has not been demonstrated by cultural approaches so far. A "mesotoga" (strain PhosAc3) that belonged to an uncultivated lineage distantly related to the thermophilic Kosmotoga genus has now been cultivated in axenic culture. It grew between 30°C and 50°C (optimum 40°C) and oxidized lactate using elemental sulphur as a terminal electron acceptor. Further genomic and physiological characterization of strain PhosAc3 will be important not only for understanding bacterial adaptation to high and moderate temperatures at small evolutionary scales, but also because "mesotoga" might play a crucial ecological role in ecosystems polluted by aromatic compounds.
authors: Laboratoire de Microbiologie IRD, UMR 180, Aix-Marseille Université, Marseille, France.
authors: Wagdi
authors: W
authors: Ben Hania
authors: Ramzi
authors: R
authors: Ghodbane
authors: Anne
authors: A
authors: Postec
authors: Céline
authors: C
authors: Brochier-Armanet
authors: Moktar
authors: M
authors: Hamdi
authors: Marie-Laure
authors: ML
authors: Fardeau
authors: Bernard
authors: B
authors: Ollivier