title: Urine proteomics in kidney and urogenital diseases: Moving towards clinical applications.
abstract: To date, multiple biomarker discovery studies in urine have been conducted. Nevertheless, the rate of progression of these biomarkers to qualification and even more clinical application is extremely low. The scope of this article is to provide an overview of main clinically relevant proteomic findings from urine focusing on kidney diseases, bladder and prostate cancers. In addition, approaches for promoting the use of urine in clinical proteomics including potential means to facilitate the validation of existing promising findings (biomarker candidates identified from previous studies) and to increase the chances for success for the identification of new biomarkers are discussed.
authors: Mosaiques Diagnostics GmbH, Hannover, Germany.
authors: Petra
authors: P
authors: Zürbig
authors: Hassan
authors: H
authors: Dihazi
authors: Jochen
authors: J
authors: Metzger
authors: Visith
authors: V
authors: Thongboonkerd
authors: Antonia
authors: A
authors: Vlahou