title: Characterization and evolution of MHC class II B genes in Ardeid birds.
abstract: Major histocompatibility complex (MHC) is a multi-gene family that is very suitable to investigate a wide range of open questions in evolutionary ecology. In this study, we characterized two expressed MHC class II B genes (DAB1 and DAB2) in the Grey Heron (Aves: Ardea cinerea). We further developed the primer pairs to amplify and sequence two MHC class II B loci in ten ardeid birds. Phylogenetic analysis revealed that different parts of the genes showed different evolutionary patterns. The exon 2 sequences tended to cluster two gene-specific lineages. In each lineage, exon 2 sequences from several species showed closer relationships than sequences within species, and two shared identical alleles were found between species (Egretta sacra and Nycticorax nycticorax; Egretta garzetta and Bubulcus ibis), supporting the hypothesis of trans-species polymorphism. In contrast, the species-specific intron 2 plus partial exon 3 tree suggested that DAB1 and DAB2 were subject to concerted evolution. GENECONV analyses showed the gene exchange played an important role in the ardeid MHC evolution.
authors: Key Laboratory of Ministry of Education for Coast and Wetland Ecosystems School of Life Sciences, Xiamen University, Siming, China.
authors: Li
authors: L
authors: Li
authors: Xiaopin
authors: X
authors: Zhou
authors: Xiaolin
authors: X
authors: Chen
references: Immunogenetics. 2005 Nov;57(10):775-81
references: 16195876
references: J Mol Evol. 2007 Nov;65(5):541-54
references: 17925996
references: Semin Immunol. 1994 Dec;6(6):411-24
references: 7654997
references: Mol Biol Evol. 1998 Mar;15(3):236-50
references: 9501491
references: Nature. 1988 Sep 15;335(6187):268-71
references: 3412487
references: Immunogenetics. 2002 Jul;54(4):230-9
references: 12136334
references: Hereditas. 1997;127(1-2):67-73
references: 9420472
references: Immunogenetics. 2004 Jun;56(3):178-91
references: 15138734
references: J Hered. 2010 Jul-Aug;101(4):448-60
references: 20200139
references: Hum Immunol. 1987 Jul;19(3):155-62
references: 3305436
references: Immunogenetics. 2009 Jun;61(6):451-61
references: 19452149
references: Immunogenetics. 2005 Apr;57(1-2):108-15
references: 15756546
references: Immunogenetics. 2007 Jul;59(7):581-92
references: 17486336
references: Annu Rev Genet. 1998;32:415-35
references: 9928486
references: Genomics. 2001 Jul;75(1-3):26-34
references: 11472064
references: J Hered. 2006 Mar-Apr;97(2):133-42
references: 16489149
references: Nature. 1999 Oct 28;401(6756):923-5
references: 10553909
references: Mol Biol Evol. 1999 Oct;16(10):1369-90
references: 10563017
references: Nucleic Acids Res. 2004 Jul 1;32(Web Server issue):W327-31
references: 15215404
references: Immunol Rev. 1999 Feb;167:119-32
references: 10319255
references: Immunogenetics. 2008 Sep;60(9):543-50
references: 18548243
references: Immunogenetics. 2006 Jul;58(7):542-58
references: 16791623
references: Mol Biol Evol. 2006 Feb;23(2):254-67
references: 16221896
references: Nature. 1999 Oct 28;401(6756):921-3
references: 10553908
references: Mol Ecol. 2003 Dec;12(12):3523-9
references: 14629367
references: Brief Bioinform. 2004 Jun;5(2):150-63
references: 15260895
references: Heredity (Edinb). 2004 Jun;92(6):534-42
references: 15162116
references: Genome Res. 2000 May;10(5):613-23
references: 10810083
references: Mol Ecol. 1995 Dec;4(6):719-29
references: 8564010
references: Immunogenetics. 1999 Nov;50(3-4):168-200
references: 10602879
references: Immunogenetics. 2004 Mar;55(12):855-65
references: 14963619
references: Mol Ecol. 2006 Apr;15(4):1153-64
references: 16599974
references: Proc Natl Acad Sci U S A. 1995 Dec 19;92(26):12200-4
references: 8618869
references: Science. 1996 Apr 5;272(5258):67-74
references: 8600539
references: Immunogenetics. 1999 Mar;49(3):158-70
references: 9914330
references: Trends Genet. 1989 Sep;5(9):300-4
references: 2686122
references: J Evol Biol. 2003 May;16(3):363-77
references: 14635837
references: Mol Biol Evol. 1999 Feb;16(2):147-56
references: 10028282
references: Genetics. 1997 Jun;146(2):655-68
references: 9178014
references: BMC Biol. 2010 Apr 01;8:29
references: 20359332
references: J Mol Evol. 2005 Oct;61(4):531-41
references: 16132469
references: Biol Lett. 2007 Jun 22;3(3):257-9; discussion 260-1
references: 17389215
references: Immunogenetics. 2003 Jan;54(10):734-41
references: 12557060
references: Hum Immunol. 2001 Jan;62(1):1-14
references: 11165710
references: Immunogenetics. 2004 Sep;56(6):420-6
references: 15351919
references: Mol Biol Evol. 1999 Apr;16(4):479-90
references: 10331274
references: Tissue Antigens. 2004 Jun;63(6):529-37
references: 15140028
references: Nature. 1988 Sep 15;335(6187):265-7
references: 3137477
references: Mol Phylogenet Evol. 2008 Apr;47(1):36-44
references: 18328734
references: Immunogenetics. 1995;41(1):1-17
references: 7806269
references: Immunogenetics. 1990;31(4):217-9
references: 2329006
references: Proc Natl Acad Sci U S A. 1998 May 26;95(11):5857-64
references: 9600884
references: Immunogenetics. 2006 Oct;58(10):805-16
references: 17021859
references: Immunol Rev. 1999 Feb;167:319-25
references: 10319270