title: The phenotype standardization project: improving pharmacogenetic studies of serious adverse drug reactions.
abstract: The ability to predict the risk for serious drug-induced adverse reactions first requires a large patient database for characterization and validation of genetic markers. The Phenotype Standardization Project (PSP) was initiated to standardize phenotypic definitions, thereby facilitating much-needed recruitment without sacrificing the reliability of patient classification. Three phenotypes have been considered in this initial phase: drug-induced liver injury, drug-induced skin injury, and drug-induced torsade de pointes.
authors: Wolfson Centre for Personalised Medicine, University of Liverpool, Liverpool, UK. munirp@liv.ac.uk
authors: M
authors: M
authors: Pirmohamed
authors: G P
authors: GP
authors: Aithal
authors: E
authors: E
authors: Behr
authors: A
authors: A
authors: Daly
authors: D
authors: D
authors: Roden