title: An alternative treatment option in tubal ectopic pregnancies with fetal heartbeat: aspiration of the embryo followed by single-dose methotrexate administration.
abstract: OBJECTIVE
  To present 13 cases of unruptured tubal ectopic pregnancies successfully treated with ultrasound-guided aspiration and local and systemic methotrexate (MTX) administration.
  
  
  METHODS
  Case series.
  
  
  METHODS
  University hospital.
  
  
  METHODS
  Thirteen women with an unruptured tubal ectopic pregnancy.
  
  
  METHODS
  Transvaginal ultrasound-guided aspiration of the tubal ectopic pregnancy followed by MTX administration into the gestational sac (half of the calculated total dose of 25 mg/m(2)) and intramuscular injection (the remaining half of the calculated total dose of 25 mg/m(2)).
  
  
  METHODS
  Recovery of the patients, successful conservative treatment of the tubal ectopic pregnancies with preservation of the fallopian tubes.
  
  
  RESULTS
  Twelve (92%) of 13 women were successfully aborted, without need for salpingectomy or salpingostomy.
  
  
  CONCLUSIONS
  Transvaginal ultrasound-guided aspiration of fetus followed by local and systemic methotrexate administration can be safely used to treat unruptured tubal ectopic pregnancies.
authors: Obstetrics and Gynecology, Division of Reproductive Endocrinology, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey.
authors: Ismail
authors: I
authors: Cepni
authors: Onur
authors: O
authors: Güralp
authors: Pelin
authors: P
authors: Ocal
authors: Ramin
authors: R
authors: Salahov
authors: Hazel
authors: H
authors: Gurleyen
authors: Mehmet
authors: M
authors: Idil