title: [Immunologic functions of total flavone of Epimedium of two species in Guizhou].
abstract: OBJECTIVE
  Comparative study on the immunologic functions of total flavones of Epimedium (TFE) in two species in Guizhou on CTX mice.
  
  
  METHODS
  To set up a hypoimmunity mouse model by CTX and give TFE in 10 days, the enhancement of immunologic functions of TFE of two species were observed with the indice of the weight of body and spleen, the spleen-index, the serum level of hemolysin, TNF-alpha and IL-2.
  
  
  RESULTS
  The spleen-index, the level of hemolysin, TNF-alpha and IL-2 of the mice decreased apparently (P < 0.01) by single ip in CTX 80 mg x kg(-1). The weight of body and spleen, the spleen-index of the mice increased, the decreased serum level of hemolysin TNF-alpha and IL-2 increased significantly (P < 0.01), by TFE of two species of 1.3, 0.65 g x kg(-1) from the mice ig.
  
  
  CONCLUSIONS
  The TFE of two species of Epimedium in Guizhou have an obvious immune enhancement effect on the non-specific immunity and specific immunity of CTX model mice. But the immune enhancement effects of the TFE from the stem and leaves of two species of Epimedium contrast insignificantly. This indicates that in addition to ICA, there must be other bioactive components that can enhance immunity.
authors: Department of Pharmacology, Guiyang College of Traditional Chinese Medicine, Guiyang 550002, China. dengwei0517@yahoo.cn
authors: Wei
authors: W
authors: Deng
authors: Minqiang
authors: M
authors: Zheng
authors: Jing
authors: J
authors: Zhang
authors: Cong
authors: C
authors: Huang
authors: Yali
authors: Y
authors: Zhang