title: Effects of allitridin on acute and chronic mouse cytomegalovirus infection.
abstract: This study investigated the effects of allitridin on acute and chronic mouse cytomegalovirus (MCMV) infections in vivo. The results demonstrated that allitridin reduced the titers of MCMV in salivary glands, and reductions in viral loads were confirmed by determining viral DNA and RNA levels in susceptible organs during the acute infection phase. Although allitridin did not eliminate MCMV, treatment reduced viral levels and facilitated healing of pathologic lesions in organs, particularly during the chronic infection phase. The results presented in this report suggest that allitridin could act as an effective agent against MCMV infections in vivo.
authors: Department of Pediatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
authors: Xing-lou
authors: XL
authors: Liu
authors: Hui
authors: H
authors: Wang
authors: Ya-nan
authors: YN
authors: Li
authors: Hai-xia
authors: HX
authors: Ge
authors: Sai-nan
authors: SN
authors: Shu
authors: Feng
authors: F
authors: Fang