title: Analysis of continuous diaphragm electromyographic signal: results from a patient with amyotrophic lateral sclerosis.
abstract: BACKGROUND
  Analysis of continuous diaphragm electromyography (dEMG) has not been well studied. We describe a system of analyzing continuous dEMG using implanted electrodes.
  
  
  METHODS
  dEMG signal was acquired via two pairs of electrodes near the diaphragm motor points. Raw bursts of dEMG signal were compared to externally captured electrocardiogram (ECG) using adaptive filtering in order to remove cardiac contamination. Differential energy levels were used to identify each dEMG burst, and average amplitude and area values from both hemidiaphragms were aggregated and averaged for the duration of the recording.
  
  
  RESULTS
  A 64-year-old patient with amyotrophic lateral sclerosis underwent three serial dEMG studies every 6 months. An average of three tracings were collected per visit, and all had excellent intertest reliability (κ > 0.8). Average dEMG area correlated with forced vital capacity and mean inspiratory pressure (r(2) > 0.9).
  
  
  CONCLUSIONS
  The approach described represents a comprehensive method for capturing and analyzing continuous diaphragm EMG signal.
authors: Division of Neurology, University Health Network, Room 5EC 306-A, 200 Elizabeth Street, Toronto, Ontario M5G 2C4, Canada. hans.katzberg@utoronto.ca
authors: Hans D
authors: HD
authors: Katzberg
authors: Daniel F
authors: DF
authors: Barros
authors: Bernard
authors: B
authors: Widrow
authors: Charles S
authors: CS
authors: Cho
authors: Yuen T
authors: YT
authors: So