title: Total synthesis of (+)-grandifloracin by iron complexation of a microbial arene oxidation product.
abstract: (+)-Grandifloracin was synthesized from sodium benzoate by means of a dearomatizing dihydroxylation that proceeds with unusual regioselectivity. Iron diene complexes formed from the arene oxidation product permit the use of otherwise inaccessible transformations. The synthetic material was shown to be antipodal to the natural product, thus determining the absolute configuration of grandifloracin for the first time.
authors: Department of Chemistry, University of Bath, Bath BA2 7AY, UK.
authors: Matthew J
authors: MJ
authors: Palframan
authors: Gabriele
authors: G
authors: Kociok-Köhn
authors: Simon E
authors: SE
authors: Lewis