title: The Hannover experience: surgical treatment of tongue cancer--a clinical retrospective evaluation over a 30 years period.
abstract: OBJECTIVE
  In this retrospective study, we present a clinical review of our experience with tongue cancer in order to obtain valid criteria for therapeutic decision-making.
  
  
  METHODS
  Between 1980 and 2009, a total of 341 patients with squamous cell carcinoma of the tongue were treated at our Department. The average follow-up was 5.2 years. 309 patients received surgical treatment, which was combined in nearly 10% with neoadjuvant and in nearly 20% with postoperative radio(chemo)therapy. 32 patients were excluded from surgery and received primary radiation.
  
  
  RESULTS
  Local and regional failure occurred in 23.9% and 20.4%, leading to a total failure rate of 37.2% after an average duration of 1,6 years. N-Status, extracapsular spread and clear margins were identified as the dominant factors for survival, which was calculated with 54.5% after 5 years.
  
  
  CONCLUSIONS
  We recommend categorical bilateral neck dissection in order to reliably remove occult lymph node metastases. Adjuvant treatment modalities should be applied more frequently in controlled clinical trials and should generally be implemented in cases with unclear margins and lymphatic spread.
  
  
  CONCLUSIONS
  This study provides new treatment strategies for primary tumour disease and for tumour recurrence.
authors: Department for Oral and Maxillofacial Surgery, Hannover Medical School Carl-Neuberg-Str. 1, 30625 Hannover, Germany.
authors: Horst
authors: H
authors: Kokemueller
authors: Department for Oral and Maxillofacial Surgery, Hannover Medical School Carl-Neuberg-Str. 1, 30625 Hannover, Germany.
authors: Majeed
authors: M
authors: Rana
authors: Department for Oral and Maxillofacial Surgery, Hannover Medical School Carl-Neuberg-Str. 1, 30625 Hannover, Germany.
authors: Jennifer
authors: J
authors: Rublack
authors: Department for Oral and Maxillofacial Surgery, Hannover Medical School Carl-Neuberg-Str. 1, 30625 Hannover, Germany.
authors: Andre
authors: A
authors: Eckardt
authors: Department for Oral and Maxillofacial Surgery, Hannover Medical School Carl-Neuberg-Str. 1, 30625 Hannover, Germany.
authors: Frank
authors: F
authors: Tavassol
authors: Department for Oral and Maxillofacial Surgery, Hannover Medical School Carl-Neuberg-Str. 1, 30625 Hannover, Germany.
authors: Paul
authors: P
authors: Schumann
authors: Department for Oral and Maxillofacial Surgery, Hannover Medical School Carl-Neuberg-Str. 1, 30625 Hannover, Germany.
authors: Daniel
authors: D
authors: Lindhorst
authors: Department for Oral and Maxillofacial Surgery, Hannover Medical School Carl-Neuberg-Str. 1, 30625 Hannover, Germany.
authors: Martin
authors: M
authors: Ruecker
authors: Department for Oral and Maxillofacial Surgery, Hannover Medical School Carl-Neuberg-Str. 1, 30625 Hannover, Germany.
authors: Nils-Claudius
authors: NC
authors: Gellrich
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