title: Neonatal lupus erythematosus: a report of four cases.
abstract: Neonatal lupus erythematosus is a very rare disease, clinically characterized by skin lesions that resemble those of subacute or discoid lupus erythematosus and/or congenital heart block. Generally, when patients have skin manifestations, they have no cardiac defects and vice-versa; however, in 10% of cases these manifestations may coexist. Other findings may include hematologic, hepatic and neurological abnormalities. This condition is caused by the transplacental passage of maternal autoantibodies against Ro (95%), La and, less frequently, U1-ribonucleoprotein (U1-RNP). The present case report describes four patients with clinical, histopathological and immunological findings compatible with neonatal lupus erythematosus, their treatment and progress.
authors: Professor Dr. Juan P. Garrahan Pediatric Hospital, Buenos Aires, Argentina. mfperez@fibertel.com.ar
authors: Maria Fernanda
authors: MF
authors: Perez
authors: Maria Eugenia de
authors: ME
authors: Torres
authors: María Marta
authors: MM
authors: Buján
authors: Agustina
authors: A
authors: Lanoël
authors: Andrea Bettina
authors: AB
authors: Cervini
authors: Adrián Martín
authors: AM
authors: Pierini