title: V-onc product expression in early phase post perinatal retrovirus infection predictive of malignancy of induced lesions.
abstract: Sixteen sarcomas developed in rats within 40 days post perinatal infection with feline sarcoma virus of Snyder-Theilen strain were examined to elucidate the association of the viral oncogene product (P85) expression with malignancy of developed sarcomas. Of these, 6 grew up to index-finger-tip-size, consisted of spindle shaped sarcoma cells and had no metastasis (group A), and 10 grew over thumb-tip-size, consisted of polygonal shaped sarcoma cells and had frequent metastasis (group B). One group A tumor and 8 group B tumors expressed P85. The v-onc product expression was thus found to be predictive of malignancy of induced tumors.
authors: CHIBA CANC CTR RES INST,DIV PATHOL,CHUO KU,CHIBA 260,JAPAN.
authors: S
authors: S
authors: Mochizuki
authors: S
authors: S
authors: Lu
authors: H
authors: H
authors: Sakai
authors: M
authors: M
authors: Fujiwara
authors: K
authors: K
authors: Maruyama