title: Cryosurgical left-sided maze procedure in patients with valvular heart disease: medium-term results.
abstract: OBJECTIVE
  We evaluated medium-term results of the left-sided maze procedure using cryoablation in patients with valvular heart disease.
  
  
  METHODS
  We retrospectively evaluated 111 patients with valvular heart disease who underwent the cryosurgical left-sided maze procedure. The mean follow-up period was 36.8 ± 24.9 months, and the mean duration of atrial fibrillation was 5.6 ± 6.0 years. The primary surgical procedure was mitral valve replacement in 42 patients, mitral valve plasty in 28, aortic valve replacement in 25, and combined aortic and mitral replacement or plasty in 16.
  
  
  RESULTS
  The 7-year actuarial survival rate was 82.9 ± 11.4% for patients in sinus rhythm and 87.0 ± 7.0% for patients with atrial fibrillation, showing no difference between the two groups (p = 0.236). At final follow-up, 86 out of 111 patients (77.5%) remained free from atrial fibrillation. Sinus rhythm was maintained in 26 of 42 patients (61.9%) in the mitral valve replacement group, 26 of 28 patients (92.9%) in the mitral valve plasty group, 15 of 17 patients (88.2%) in the aortic valve replacement group, and 18 of 24 patients (75.0%) in the combined aortic and mitral replacement or plasty group. The overall actuarial rate of freedom from atrial fibrillation at 5 years after surgery was 70.4 ± 6.0%.
  
  
  CONCLUSIONS
  The cryosurgical left-sided maze procedure is a safe, simple, and excellent operation for medically refractory atrial fibrillation.
authors: The Jikei University School of Medicine, Department of Cardiac Surgery, Tokyo, Japan. ysakamoto@jikei.ac.jp
authors: Yoshimasa
authors: Y
authors: Sakamoto
authors: Hiromitsu
authors: H
authors: Takakura
authors: Katsuhisa
authors: K
authors: Onoguchi
authors: Takashi
authors: T
authors: Hachiya
authors: Tatsuumi
authors: T
authors: Sasaki
authors: Michio
authors: M
authors: Yoshitake
authors: Kazuhiro
authors: K
authors: Hashimoto