title: Intraoperative measurement of peritumoral regional cortical cerebral blood flow.
abstract: Peritumoral regional cortical blood flow (rCoBF) was studied intraoperatively using thermal diffusion flowmetry. Histology included glioblastomas (n=5), anaplastic astrocytoma (n=1), pilocytic astrocytomas (n=2), metastatic melanoma (n=1), and trigeminal schwannoma (n=1). Pre-resection rCoBF values were low in all but two tumors where perfusion was in the low normal range. Post-resection rCoBF values were either low or normalized. Seizure activity was documented in a pilocytic astrocytoma with a significant rCoBF increase during resection. Our findings indicate that hypoperfusion in the cortex adjacent to malignant brain tumors is the result of primary metabolic failure and tumor pressure ischemia.
authors: UNIV OKLAHOMA,HLTH SCI CTR,DEPT NEUROSURG,OKLAHOMA CITY,OK 73190.
authors: P
authors: P
authors: Sioutos
authors: L
authors: L
authors: Carter
authors: M
authors: M
authors: Weinand
authors: A
authors: A
authors: Hamilton
authors: J
authors: J
authors: Nees
authors: J
authors: J
authors: Orosco