title: N-(2,5-Dimeth-oxy-phen-yl)-N'-(4-hy-droxy-pheneth-yl)urea.
abstract: In the title compound, C(17)H(20)N(2)O(4), the 2,5-dimeth-oxy-phenyl unit is almost planar, with an r.m.s. deviation of 0.015 Å. The dihedral angle between the 2,5-dimeth-oxy-phenyl ring and the urea plane is 20.95 (8)°. The H atoms of the urea NH groups are positioned syn to each other. The mol-ecular structure is stabilized by a short intra-molecular N-H⋯O hydrogen bond. In the crystal, inter-molecular N-H⋯O and O-H⋯O hydrogen bonds link the mol-ecules into a three-dimensional network.
authors: Hyeong
authors: H
authors: Choi
authors: Byung Hee
authors: BH
authors: Han
authors: Yong Suk
authors: YS
authors: Shim
authors: Sung Kwon
authors: SK
authors: Kang
authors: Chang Keun
authors: CK
authors: Sung
references: Bioorg Med Chem. 2001 May;9(5):1233-40
references: 11377181
references: Bioorg Med Chem. 2000 Jul;8(7):1749-55
references: 10976523
references: Exp Dermatol. 1995 Apr;4(2):79-81
references: 7640879
references: Biochem Biophys Res Commun. 2001 Jul 13;285(2):257-61
references: 11444834
references: Biol Pharm Bull. 1995 Aug;18(8):1076-80
references: 8535399
references: Dermatol Surg. 1996 May;22(5):443-7
references: 8634807
references: Acta Crystallogr A. 2008 Jan;64(Pt 1):112-22
references: 18156677
references: Bioorg Med Chem Lett. 2010 May 1;20(9):2991-3
references: 20359890
references: Bioorg Med Chem Lett. 2006 Jan 15;16(2):324-30
references: 16275084
references: Bioorg Med Chem. 2006 Jan 15;14(2):344-51
references: 16198580
references: Br J Dermatol. 1981 Jun;104(6):659-65
references: 6788064
references: J Pharm Pharmacol. 1994 Dec;46(12):982-5
references: 7714722