title: Treating humoral rejection after cardiac transplantation.
abstract: Whereas effective strategies are available to treat acute cellular cardiac rejection, humoral rejection, also called vascular or antibody-mediated rejection, is more difficult to manage. Antibody-mediated (non-cellular) rejections (AMR) are rare and few successfully treated cases have been described in the literature. We report on a female patient, diagnosed with humoral rejection, leading to severe ventricular dysfunction and haemodynamic compromise, two months after transplantation. The patient received a combination therapy, consisting of plasmapheresis and immunoglobulins, which resulted in complete resolution of immunohistochemical signs of AMR. In this report, we will overview AMR and discuss several treatment modalities.
authors: Department of Cardiology, Antwerp University Hospital, Edegem, Belgium. jef.verheyen@uza.be
authors: Jef
authors: J
authors: Verheyen
authors: Tom
authors: T
authors: Vermeulen
authors: Karin
authors: K
authors: Janssen Van Doorn
authors: Christiaan
authors: C
authors: Vrints
authors: Viviane
authors: V
authors: Conraads