title: Bile acid-based cage compounds with lipophilic outer shells and inner cavities.
abstract: The uniquely functionalized steroid-based cyclodimers 4, cis-5, and trans-5 have been synthesized and fully characterized.The cyclodimer 5, with a cis-trans ratio of 3:1, is obtained by coupling the terminal alkenes of two 4-pentenoate groups on a cyclodimer 4 via Grubbs' intramolecular ring-closing metathesis. The crystal structure shows cis-5 to be a cagelike cyclic oligomer bridged by the flexible oct-4-enedioate link.
authors: Department of Chemistry, University of Missouri-Kansas City, 5100 Rockhill Road, Kansas City, Missouri 64110, USA.
authors: Xinyan
authors: X
authors: Bai
authors: Charles
authors: C
authors: Barnes
authors: Robert A
authors: RA
authors: Pascal
authors: Xueyi
authors: X
authors: Chen
authors: Jerry Ray
authors: JR
authors: Dias