title: Moyamoya syndrome associated with neurofibromatosis type I in a pediatric patient.
abstract: BACKGROUND
  Neurofibromatosis type 1 (NF-1) is the most prevalent autosomal dominant genetic disorder among humans. Moyamoya disease is a cerebral vasculopathy that is only rarely observed in association with NF-1, particularly in the pediatric age range. The present study reports an occurrence of this association in an infant.
  
  
  METHODS
  An eight-month-old female presented convulsive seizures with clonic movements. The patient suffered an ischemic stroke with hemiparesis. Magnetic resonance imaging revealed radiological findings compatible with moyamoya disease. The diagnosis of NF-1 was made at the age of 20 months.
  
  
  CONCLUSIONS
  Despite the rarity of this association in childhood, children with focal neurological symptoms and a diagnosis of NF-1 deserve to be investigated for moyamoya syndrome.
authors: Division of Pediatric Oncology, Department of Pediatrics, Ribeirão Preto School of Medicine, University of São Paulo, Brazil. guimedicina@gmail.com
authors: Luiz Guilherme
authors: LG
authors: Darrigo Júnior
authors: Elvis Terci
authors: ET
authors: Valera
authors: André de Aboim
authors: Ade A
authors: Machado
authors: Antonio Carlos Dos
authors: AC
authors: Santos
authors: Carlos Alberto
authors: CA
authors: Scrideli
authors: Luiz Gonzaga
authors: LG
authors: Tone
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