title: Selective formation of 1,5-substituted sulfonyl triazoles using acetylides and sulfonyl azides.
abstract: The reaction of acetylides with sulfonyl azides was found to selectively form 1,5-substituted sulfonyl triazoles. This reaction thus provides access to the regioisomeric product as compared to the popular copper-catalyzed azide-alkyne cycloaddition. The reaction is efficient and selective with a variety of alkyne sources and sulfonyl azides and can incorporate an additional electrophile to yield 1,4,5-trisubstituted sulfonyl triazoles.
authors: Department of Chemistry and Biochemistry, University of North Carolina at Greensboro, Greensboro, North Carolina 27402, USA.
authors: Maria Elena
authors: ME
authors: Meza-Aviña
authors: Mudita Kishor
authors: MK
authors: Patel
authors: Cylivia B
authors: CB
authors: Lee
authors: Thomas J
authors: TJ
authors: Dietz
authors: Mitchell P
authors: MP
authors: Croatt