title: From polyesters to polyamides via O-N acyl migration: an original multi-transfer reaction.
abstract: A new strategy for the synthesis of polyamides from polyesters of hydroxyl-containing amino acids using a multi O-N acyl transfer reaction was developed. This original approach allowed the synthesis of three generations of polymers from the same starting monomer. The polymerization of N-benzyloxycarbonyl-serine and its γ-homologated derivative provided the Z-protected polyesters; then the water-soluble polycationic polyesters were obtained by removal of the Z-protecting group; and finally the polyamides were obtained by a base-induced multi O-N acyl transfer, both in aqueous or organic medium. The key step transfer reaction was monitored by the disappearance and appearance of characteristic NMR proton signals and IR bands of polyesters and polyamides.
authors: Institut des Biomolécules Max Mousseron, UMR5247 CNRS, Université Montpellier 1 et 2, 15 Avenue Charles Flahault, 34000 Montpellier, France.
authors: Julien
authors: J
authors: Tailhades
authors: Sébastien
authors: S
authors: Blanquer
authors: Benjamin
authors: B
authors: Nottelet
authors: Jean
authors: J
authors: Coudane
authors: Gilles
authors: G
authors: Subra
authors: Pascal
authors: P
authors: Verdié
authors: Etienne
authors: E
authors: Schacht
authors: Jean
authors: J
authors: Martinez
authors: Muriel
authors: M
authors: Amblard