title: Effect of carotid artery stenting on the release of S-100B and neurone-specific enolase.
abstract: Serum levels of S-100B and neurone-specific enolase (NSE) reflect cerebral injury in a variety of neurological conditions such as stroke, traumatic brain injury, and cardiac arrest. There are limited data on the release of S-100B and NSE following carotid artery stenting (CAS). In 22 patients undergoing CAS, serial blood samples for S-100B and NSE were collected before and 2, 4, and 6 to 8 hours after the procedure. A group of 20 patients with significant CAS undergoing purely diagnostic angiography served as controls. A significant increase in S-100B levels was observed 2 hours after the procedure in patients with CAS (P = .001) with a gradual decline over the next hours. In contrast, patients who underwent purely diagnostic angiography did not show significant changes in S-100B levels up to 8 hours after the procedure. Neither patients with CAS nor those undergoing diagnostic angiography displayed any significant changes in serial NSE levels.
authors: University of Leipzig-Heart Center, Department of Internal Medicine/Cardiology, Germany.
authors: Christiane
authors: C
authors: Mattusch
authors: Klaus-Werner
authors: KW
authors: Diederich
authors: Andrej
authors: A
authors: Schmidt
authors: Dierk
authors: D
authors: Scheinert
authors: Holger
authors: H
authors: Thiele
authors: Gerhard
authors: G
authors: Schuler
authors: Steffen
authors: S
authors: Desch