title: Increased expression of exon 2 deleted MEFV transcript in familial Mediterranean fever patients.
abstract: A defect in MEFV gene expression regulation has been implicated in familial Mediterranean fever (FMF) etiopathophysiology. Here we show significantly higher expression level in second exon lacking MEFV transcript in FMF patients compared with healthy controls (P=0.026). Our results also point out a possible role of exon 2 deleted MEFV transcript in FMF pathogenesis.
authors: Molecular Biology Genetics and Biotechnology Graduate Program, Institute of Science and Technology, Istanbul Technical University, Istanbul, Turkey.
authors: A K
authors: AK
authors: Kirectepe
authors: G Celikyapi
authors: GC
authors: Erdem
authors: N
authors: N
authors: Senturk
authors: N
authors: N
authors: Arisoy
authors: G
authors: G
authors: Hatemi
authors: H
authors: H
authors: Ozdogan
authors: O
authors: O
authors: Kasapcopur
authors: E
authors: E
authors: Tahir Turanli