title: 1-(3-Chloro-4-fluoro-phen-yl)-5-(2-diazo-acet-yl)-4-phenyl-pyrrolidin-2-one.
abstract: In the title compound, C(18)H(13)ClFN(3)O(2), the pyrrolidine ring adopts an envelope conformation and the planar part is rotated by 4.3 (6)° from the plane of the benzene ring and is almost perperdicular both to the diazo-acetyl unit [dihedral angle = 78.93 (7)°] and the phenyl ring [dihedral angle = 86.07 (7)°]. In the crystal, mol-ecules are linked into a three-dimensional framework by C-H⋯O inter-actions. The mol-ecular conformation is stabilized by an intra-molecular C-H⋯O hydrogen bond.
authors: Jayanta Kumar
authors: JK
authors: Ray
authors: Pranab
authors: P
authors: Haldar
authors: M
authors: M
authors: Canle L
authors: M I
authors: MI
authors: Fernández P
authors: J A
authors: JA
authors: Santaballa
references: Bioorg Med Chem. 1994 Dec;2(12):1417-21
references: 7788305
references: Acta Crystallogr B. 2002 Jun;58(Pt 3 Pt 1):380-8
references: 12037359
references: Acta Crystallogr A. 2008 Jan;64(Pt 1):112-22
references: 18156677
references: Bioorg Med Chem. 1998 Dec;6(12):2397-403
references: 9925297
references: Acta Crystallogr D Biol Crystallogr. 2009 Feb;65(Pt 2):148-55
references: 19171970
references: Acta Crystallogr C. 2004 Mar;60(Pt 3):o163-5
references: 15004370
references: Chem Commun (Camb). 2005 Jun 28;(24):2995-3001
references: 15959566