title: Summary of integrative medicine for severe acute pancreatitis: 26-year clinical experiences and a report of 1 561 cases.
abstract: OBJECTIVE
  To investigate the changing trends of clinical management for severe acute pancreatitis (SAP) with integrative medicine.
  
  
  METHODS
  Clinical data of 1 561 patients with SAP from 1980 to 2005 was retrospectively analyzed. The mortality and morbidity of complications were compared.
  
  
  RESULTS
  Of the 1 561 patients, 400 patients accepted surgical operation, while the rest were treated conservatively with integrative medicine. There was a change toward conservative management together with Chinese purgative herbal medication use after 1990 (22.4% from 1980-1990 compared with 45.5% from 1991-1993) because of high postoperative mortality. From 1994-2005, the treatment integrating Western medicine with Chinese herbal medications came to be preferred over the classic Western operation-based method. This change was associated with decreased morbidity (35.4% in 1980-1990 compared with 24.7% in 1991-1993 and 11.0% in 1994-2005, P<0.05) and lower mortality (40.52% of 1980-1990 compared with 17.17% of 1991-1993 and <10.25% of 1994-2005, P<0.05).
  
  
  CONCLUSIONS
  The combination of conservative management with Chinese herbal medicines is preferable to classic Western medicine treatment to reduce morbidity and mortality of SAP, while surgery becomes a supplemental option.
authors: Department of Integrated Traditional Chinese and Western Medicine, West China Hospital, Sichuan University, Chengdu, China.
authors: Han-lin
authors: HL
authors: Gong
authors: Wen-fu
authors: WF
authors: Tang
authors: Yan-yi
authors: YY
authors: Ren
authors: Mei-hua
authors: MH
authors: Wan
authors: Guang-yuan
authors: GY
authors: Chen
authors: Qing
authors: Q
authors: Xia
authors: Xi
authors: X
authors: Huang
references: Pancreas. 1998 Apr;16(3):312-5
references: 9548672
references: Radiology. 1985 Sep;156(3):767-72
references: 4023241
references: Nihon Rinsho. 2004 Nov;62(11):2009-14
references: 15552882
references: Hua Xi Yi Ke Da Xue Xue Bao. 2000 Sep;31(3):402-4
references: 12545846
references: Chin J Dig Dis. 2005;6(1):47-51
references: 15667559
references: Br J Surg. 1989 Mar;76(3):264-7
references: 2720323
references: Pancreatology. 2005;5(2-3):132-44
references: 15849484
references: Curr Opin Crit Care. 2000 Aug;6(4):271-275
references: 11329511
references: BMJ. 2004 Jun 12;328(7453):1407
references: 15175229
references: Chirurgia (Bucur). 2005 Sep-Oct;100(5):445-50
references: 16372670
references: Pancreas. 2003 Nov;27(4):291-6
references: 14576489
references: World J Gastroenterol. 2000 Feb;6(1):115-118
references: 11819536
references: J Clin Gastroenterol. 2002 Jul;35(1):50-60
references: 12080227
references: Zhong Xi Yi Jie He Xue Bao. 2009 Sep;7(9):868-72
references: 19747444
references: Ann Ital Chir. 1995 Mar-Apr;66(2):209-15
references: 7668497
references: Eur J Surg. 1995 Mar;161(3):187-92
references: 7599297
references: Nat Clin Pract Gastroenterol Hepatol. 2005 Oct;2(10):473-83
references: 16224479
references: Crit Care Med. 1985 Oct;13(10):818-29
references: 3928249
references: Br J Surg. 2006 Jun;93(6):738-44
references: 16671062
references: Zhonghua Wai Ke Za Zhi. 2000 Aug;38(8):625-9
references: 11832126
references: Curr Gastroenterol Rep. 2004 Apr;6(2):99-103
references: 15191686
references: J Gastroenterol. 2003;38(3):305-7
references: 12693385
references: World J Gastroenterol. 2005 Sep 14;11(34):5309-13
references: 16149137
references: Br J Surg. 1988 Aug;75(8):793-5
references: 3167531
references: Acta Chir Scand. 1990 Nov-Dec;156(11-12):775-80
references: 2075775
references: Basic Clin Pharmacol Toxicol. 2005 Dec;97(6):342-50
references: 16364048
references: JOP. 2005 Sep 10;6(5):438-44
references: 16186665
references: Pancreatology. 2005;5(1):10-9
references: 15775694
references: Nutr Clin Pract. 2004 Feb;19(1):5-15
references: 16215091
references: Rev Esp Enferm Dig. 2002 Sep;94(9):523-32
references: 12587232
references: Gut. 2005 Mar;54(3):426-36
references: 15710995
references: Zhong Xi Yi Jie He Xue Bao. 2009 Jul;7(7):651-6
references: 19615319