title: Citronellol and geraniol, components of rose oil, activate peroxisome proliferator-activated receptor α and γ and suppress cyclooxygenase-2 expression.
abstract: We evaluated the effects of rose oil on the peroxisome proliferator-activated receptor (PPAR) and cyclooxygenase-2 (COX-2). Citronellol and geraniol, the major components of rose oil, activated PPARα and γ, and suppressed LPS-induced COX-2 expression in cell culture assays, although the PPARγ-dependent suppression of COX-2 promoter activity was evident only with citronellol, indicating that citronellol and geraniol were the active components of rose oil.
authors: Department of Food Science and Nutrition, Nara Women's University, Nara, Japan.
authors: Michiko
authors: M
authors: Katsukawa
authors: Rieko
authors: R
authors: Nakata
authors: Satomi
authors: S
authors: Koeji
authors: Kazuyuki
authors: K
authors: Hori
authors: Saori
authors: S
authors: Takahashi
authors: Hiroyasu
authors: H
authors: Inoue