title: Exo-cyclopamine--a stable and potent inhibitor of hedgehog-signaling.
abstract: The combination of theoretical and computational studies with organic synthesis and biological investigations has led to exo-cyclopamine. This stable and highly potent derivative of cyclopamine promises big potential as an experimental drug against several types of human cancer.
authors: Institut für Organische Chemie, Fakultät für Chemie und Mineralogie, Universität Leipzig, Johannisallee 29, D-04103 Leipzig, Germany.
authors: Philipp
authors: P
authors: Heretsch
authors: Anita
authors: A
authors: Büttner
authors: Lito
authors: L
authors: Tzagkaroulaki
authors: Stefan
authors: S
authors: Zahn
authors: Barbara
authors: B
authors: Kirchner
authors: Athanassios
authors: A
authors: Giannis