title: Absolute configuration of odorine.
abstract: The title compound, known as odorine or roxburghiline {systematic name: (S)-N-[(R)-1-cinnamoylpyrrolidin-2-yl]-2-methyl-butanamide}, C(18)H(24)N(2)O(2), is a nitro-genous compound isolated from the leaves of Aglaia odorata. The absolute configuration was determined by refinement of the Flack parameter with data collected using Cu Kα radiation showing positions 2 and 2' to be S and R, respectively. The pyrrolidine ring adopts an envelope conformation. In the crystal, mol-ecules are linked into chains along [010] by inter-molecular N-H⋯O hydrogen bonds.
authors: Hoong-Kun
authors: HK
authors: Fun
authors: Suchada
authors: S
authors: Chantrapromma
authors: Orapun
authors: O
authors: Yodsaoue
authors: Chatchanok
authors: C
authors: Karalai
references: J Agric Food Chem. 2000 Apr;48(4):1400-4
references: 10775404
references: J Nat Prod. 1993 Apr;56(4):473-7
references: 8496701
references: Acta Crystallogr D Biol Crystallogr. 2009 Feb;65(Pt 2):148-55
references: 19171970
references: Biol Pharm Bull. 2001 Nov;24(11):1282-5
references: 11725964
references: Acta Crystallogr A. 2008 Jan;64(Pt 1):112-22
references: 18156677
references: J Nat Prod. 1998 Dec;61(12):1482-90
references: 9868148