title: Interleukin-28B genotyping by melt-mismatch amplification mutation assay PCR analysis using single nucleotide polymorphisms rs12979860 and rs8099917, a useful tool for prediction of therapy response in hepatitis C patients.
abstract: Several studies have identified associations between single nucleotide polymorphisms (SNPs) occurring near the interleukin-28B (IL-28B) gene and response to antiviral treatment among hepatitis C virus (HCV) patients. Here, we describe a reliable melt-mismatch amplification mutation assay (melt-MAMA) PCR-based genotyping method for IL-28B which can be used in the management of HCV patients, helping to better define the course of therapy.
authors: Unidad de Investigación Multidisciplinaria, Facultad de Estudios Superiores Cuautitlán, Universidad Nacional Autónoma de México, Mexico City, Mexico.
authors: Salvador
authors: S
authors: Fonseca-Coronado
authors: Gilberto
authors: G
authors: Vaughan
authors: Mayra Yolanda
authors: MY
authors: Cruz-Rivera
authors: Juan Carlos
authors: JC
authors: Carpio-Pedroza
authors: Karina
authors: K
authors: Ruiz-Tovar
authors: Juan Alberto
authors: JA
authors: Ruiz-Pacheco
authors: Alejandro
authors: A
authors: Escobar-Gutiérrez
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