title: Invasive Myceliophthora thermophila infection mimicking invasive aspergillosis in a neutropenic patient: a new cause of cross-reactivity with the Aspergillus galactomannan serum antigen assay.
abstract: Myceliophthora thermophila is a thermophilic mould widely found in the environment but rarely responsible for human infections. We describe a case of invasive Myceliophthora thermophila infection mimicking invasive aspergillosis in a neutropenic patient with haematological malignancy. Cross-reactivity with Aspergillus galactomannan assay (GM) was demonstrated by repeated positive results and confirmed by cross-reaction between the fungal isolate and the GM assay. The patient was successfully treated with voriconazole. Potential GM cross-reactivity must be considered in future studies including patients categorized as having probable invasive aspergillosis using the GM as the only mycological criterion.
authors: Laboratoire de Parasitologie-Mycologie, CHU de Nantes, Nantes, France. florent.morio@chu-nantes.fr
authors: Florent
authors: F
authors: Morio
authors: François
authors: F
authors: Fraissinet
authors: Thomas
authors: T
authors: Gastinne
authors: Patrice
authors: P
authors: Le Pape
authors: Jacques
authors: J
authors: Delaunay
authors: Lynne
authors: L
authors: Sigler
authors: Connie Fe C
authors: CF
authors: Gibas
authors: Michel
authors: M
authors: Miegeville