title: Xanthelasma palpebrarum treatment with a 1,450-nm-diode laser.
abstract: BACKGROUND
  Various treatments of xanthelasma palpebrarum have been studied, including surgical excision, treatment with chemicals, and ablative laser therapy, but these methods have some disadvantages. Recently, nonablative laser therapy has been proposed as a treatment for xanthelasma palpebrarum.
  
  
  OBJECTIVE
  To investigate the efficacy and safety of a 1,450-nm-diode laser in the treatment of xanthelasma.
  
  
  METHODS
  Sixteen patients were treated using a 1,450-nm-diode laser. Fluences of 12 J/cm(2) , a 6-mm spot size, and a dynamic cooling device setting of 20 to 30 ms were used. One to four treatments 4 to 6 weeks apart were given to each patient. Photographs were taken before each treatment session and 4 to 6 weeks after the last treatment.
  
  
  RESULTS
  Two (12.5%), eight (50%), and four (25%) of the 16 patients were scored as having some (20-40% clearing), moderate (40-60% clearing), and marked (60-80% clearing) improvement, respectively. Focal mild transient hyperpigmentation was noted in five patients. Post-treatment local swelling lasted 3 to 4 days.
  
  
  CONCLUSIONS
  The 1,450-nm-diode laser treatment is a new, valuable treatment option for xanthelasma palpebrarum, offering relatively mild side effects. Studies including long term follow up and a comparison with alternative treatment modalities are necessary to further assess the clinical utility of this treatment. The authors have indicated no significant interest with commercial supporters.
authors: Department of Dermatology, College of Medicine, Hallym University, Anyang-si, Gyeonggi-do, Korea Drs Woo and Hann's Skin and Laser Center, Seoul, Korea.
authors: Eun Joo
authors: EJ
authors: Park
authors: Sung Hwan
authors: SH
authors: Youn
authors: Eun Byul
authors: EB
authors: Cho
authors: Geun Soo
authors: GS
authors: Lee
authors: Seung Kyung
authors: SK
authors: Hann
authors: Kwang Ho
authors: KH
authors: Kim
authors: Kwang Joong
authors: KJ
authors: Kim