title: Genome-scale techniques highlight the epigenome and redefine fundamental principles of gene regulation.
abstract: The regulation of gene expression represents one of the most fundamental of biologic processes that controls cellular proliferation, differentiation, and function. Recent technological advances in genome-wide annotation together with bioinformatic/computational analyses have contributed significantly to our understanding of transcriptional regulation at the epigenomic and regulomic levels. This perspective outlines the techniques that are being utilized and summarizes a few of the outcomes.
authors: Department of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706, USA. pike@biochem.wisc.edu
authors: J Wesley
authors: JW
authors: Pike
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