title: Neoadjuvant intra-arterial infusion chemotherapy for invasive thymoma.
abstract: Four patients with stage III or IVa invasive thymoma successfully underwent surgical intervention and radiotherapy following neoadjuvant intra-arterial chemotherapy including 50 mg/m(2) of cisplatin and 20 mg/m(2) of adriamycin. Remarkable reduction rates (60% or more) of the tumor size were obtained without significant side effects. About 4 weeks after neoadjuvant chemotherapy, an extended thymectomy including invaded organs was easily performed with a small amount of intraoperative bleeding. All patients but one are currently alive and disease-free. This method may be a new therapeutic strategy in the management of invasive thymoma.
authors: Y
authors: Y
authors: Otani
authors: I
authors: I
authors: Yoshida
authors: S
authors: S
authors: Ishikawa
authors: A
authors: A
authors: Ohtaki
authors: T
authors: T
authors: Takahashi
authors: T
authors: T
authors: Koyano
authors: Y
authors: Y
authors: Hasegawa
authors: S
authors: S
authors: Sakata
authors: Y
authors: Y
authors: Morishita