title: Early port-site metastasis during neoadjuvant chemotherapy in advanced stage ovarian cancer: report of two cases.
abstract: Port-site metastases in gynecological malignancies subsequent to laparoscopy have been reported with an incidence of 1.1-16%. These metastases tend to be disappearing after primary debulking surgery and subsequent primary chemotherapy. Local resection, chemotherapy and/or radiotherapy have been defined in the management of these metastases with enhanced clinical success. However, in extremely rare cases these metastases were also defined very early during neoadjuvant chemotherapy. Herein, we present two ovarian cancer cases which are clinically diagnosed with port site metastasis during neoadjuvant chemotherapy following diagnostic laparoscopy. Although neoadjuvant chemotherapy is sometimes needed in cases of fully advanced ovarian cancers, port-site metastasis may be encountered during neoadjuvant chemotherapy. The possible poor prognosis of these patients, especially those who have ascites, should make us careful in performing diagnostic laparoscopy with preventive measures for port-site metastasis and to start the chemotherapy immediately.
authors: Department of Obstetrics and Gynecology, Ankara University Faculty of Medicine, Ankara, Turkey.
authors: Batuhan
authors: B
authors: Ozmen
authors: Yavuz Emre
authors: YE
authors: Sükür
authors: Cem Somer
authors: CS
authors: Atabekoglu
authors: Aylin Okçu
authors: AO
authors: Heper
authors: Murat
authors: M
authors: Sönmezer
authors: Mete
authors: M
authors: Güngör
references: Obstet Gynecol. 1994 Nov;84(5):765-9
references: 7936509
references: Gynecol Oncol. 2005 Mar;96(3):729-35
references: 15721418
references: Gynecol Oncol. 2008 Sep;110(3):354-9
references: 18572226
references: Gynecol Oncol. 1998 Dec;71(3):431-6
references: 9887245
references: Gynecol Oncol. 2006 Mar;100(3):455-61
references: 16325244
references: Am J Obstet Gynecol. 2003 Jul;189(1):16-21
references: 12861132
references: Gynecol Oncol. 2003 Oct;91(1):179-89
references: 14529679
references: Gynecol Oncol. 1996 Feb;60(2):233-7
references: 8631544
references: Am J Obstet Gynecol. 1999 Sep;181(3):536-41
references: 10486460
references: JSLS. 2004 Apr-Jun;8(2):133-9
references: 15119657
references: Gynecol Oncol. 1999 Jan;72(1):38-44
references: 9889027
references: Int J Gynecol Cancer. 2005 Sep-Oct;15(5):776-9
references: 16174223
references: Endoscopy. 1978 May;10(2):127-30
references: 149005
references: Gynecol Oncol. 2002 Jun;85(3):529-31
references: 12051886