title: fMRI investigation of speed-accuracy strategy switching.
abstract: Switching between rapid and accurate responses is an important aspect of decision-making. However, the brain mechanisms important to smoothly change the speed-accuracy strategy remain mostly unclear. This issue was addressed here by using functional magnetic resonance imaging (fMRI). On each trial, right-handed healthy participants had to stress speed or accuracy in performing a color discrimination task on a target stimulus according to the instructions given by an initial cue. Participants were capable of trading speed for accuracy and vice versa. Analyses of cue-related fMRI activations revealed a significant recruitment of left middle frontal gyrus and right cerebellum when switching from speed to accuracy. The left superior parietal lobule was activated in the same switching condition but only after the target onset. The anterior cingulate cortex was more recruited, also after target presentation, when speed had to be maintained from one trial to the next. These results are interpreted within a theoretical framework that attributes a role in criterion-setting to the left lateral prefrontal cortex, perceptual evidence accumulation to the superior parietal lobule, and action energization to the anterior cingulate cortex, extending previous findings to the domain of speed-accuracy tradeoff regulations.
authors: Rotman Research Institute at Baycrest, Toronto, Canada. vallesi@sissa.it
authors: Antonino
authors: A
authors: Vallesi
authors: Anthony R
authors: AR
authors: McIntosh
authors: Cristiano
authors: C
authors: Crescentini
authors: Donald T
authors: DT
authors: Stuss
references: Proc Biol Sci. 2008 Oct 22;275(1649):2353-61
references: 18611852
references: Science. 2007 Nov 9;318(5852):987-90
references: 17962523
references: Exp Brain Res. 2000 Jul;133(1):55-65
references: 10933210
references: Hum Brain Mapp. 2001 Mar;12(3):131-43
references: 11170305
references: Clin Neurophysiol. 2008 Nov;119(11):2559-69
references: 18824403
references: Trends Neurosci. 2010 Jan;33(1):10-6
references: 19819033
references: J Chem Neuroanat. 2003 Dec;26(4):317-30
references: 14729134
references: Trends Ecol Evol. 2009 Jul;24(7):400-7
references: 19409649
references: Neuroimage. 2001 Feb;13(2):250-61
references: 11162266
references: Eur J Neurosci. 1999 Mar;11(3):1011-36
references: 10103094
references: Annu Rev Neurosci. 2007;30:535-74
references: 17600525
references: Int J Psychophysiol. 2003 Feb;47(2):175-83
references: 12568947
references: PLoS One. 2008 Jul 09;3(7):e2635
references: 18612380
references: J Neurophysiol. 2010 Mar;103(3):1179-94
references: 20032247
references: J Neurosci. 2006 Oct 4;26(40):10091-9
references: 17021165
references: Philos Trans R Soc Lond B Biol Sci. 2007 Sep 29;362(1485):1641-54
references: 17428775
references: Science. 2004 Oct 15;306(5695):443-7
references: 15486290
references: J Cogn Neurosci. 2011 Apr;23(4):867-79
references: 20350183
references: Front Neurosci. 2008 Jul 07;2(1):79-85
references: 18982110
references: Nat Rev Neurosci. 2008 Aug;9(8):613-25
references: 18641668
references: Neuropsychologia. 2005;43(3):396-417
references: 15707616
references: J Neurophysiol. 2001 Oct;86(4):1916-36
references: 11600651
references: Neuropsychology. 2002 Oct;16(4):500-13
references: 12382989
references: Science. 2000 Jun 9;288(5472):1835-8
references: 10846167
references: Nat Neurosci. 2006 May;9(5):682-9
references: 16604069
references: Proc Natl Acad Sci U S A. 2006 Jun 27;103(26):10023-8
references: 16785427
references: J Comp Neurol. 1993 Oct 8;336(2):211-28
references: 7503997
references: J Neurosci. 2002 Nov 1;22(21):9475-89
references: 12417672
references: Exp Brain Res. 2007 Jan;176(3):440-7
references: 16917771
references: J Neurophysiol. 2000 Mar;83(3):1701-9
references: 10712490
references: Cereb Cortex. 1996 May-Jun;6(3):342-53
references: 8670662
references: Psychophysiology. 2000 Mar;37(2):216-23
references: 10731771
references: J Neurosci. 2010 May 26;30(21):7434-46
references: 20505110
references: Neurosci Lett. 2005 Mar 16;376(3):188-93
references: 15721219
references: J Neurosci. 2004 Oct 6;24(40):8847-52
references: 15470151
references: J Cogn Neurosci. 2001 Jul 1;13(5):698-710
references: 11506665
references: J Neurosci. 2005 Nov 9;25(45):10420-36
references: 16280581
references: Nat Neurosci. 2001 Sep;4(9):948-52
references: 11528428
references: Neuron. 2002 Oct 10;36(2):299-308
references: 12383783
references: Neuropsychologia. 2009 Dec;47(14):3162-73
references: 19651150
references: J Exp Psychol Learn Mem Cogn. 2006 Jan;32(1):101-17
references: 16478344
references: Mem Cognit. 2004 Oct;32(7):1206-20
references: 15813501
references: Nat Rev Neurosci. 2001 Jun;2(6):417-24
references: 11389475
references: Cereb Cortex. 2006 Nov;16(11):1623-30
references: 16400154
references: Neuroimage. 2004 Oct;23(2):604-12
references: 15488410
references: Behav Res Methods. 2007 Nov;39(4):767-75
references: 18183889
references: Trends Cogn Sci. 2004 Dec;8(12):539-46
references: 15556023
references: Prog Neurobiol. 1996 Nov;50(4):381-425
references: 9004351
references: Neuroimage. 2009 Apr 1;45(2):537-48
references: 19162201
references: J Cogn Neurosci. 2011 Apr;23(4):801-15
references: 20350184
references: Neuropsychologia. 1971 Mar;9(1):97-113
references: 5146491
references: J Exp Psychol. 1966 Jun;71(6):849-57
references: 5939364
references: Nat Neurosci. 2000 May;3(5):516-20
references: 10769394
references: Neuroscientist. 2009 Apr;15(2):166-79
references: 19307423
references: J Cogn Neurosci. 2008 Nov;20(11):1952-65
references: 18416686
references: J Neurosci. 2001 Jul 15;21(14):5262-71
references: 11438601
references: Eur J Neurosci. 2001 Oct;14(8):1405-11
references: 11703468
references: Annu Rev Neurosci. 1986;9:357-81
references: 3085570
references: Brain Res Cogn Brain Res. 2000 Sep;10(1-2):1-9
references: 10978687
references: Eur J Neurosci. 2001 Nov;14(10):1633-50
references: 11860458
references: Prog Brain Res. 1990;85:119-46
references: 2094891
references: J Neurosci. 2009 Jul 15;29(28):9115-22
references: 19605648
references: Proc Natl Acad Sci U S A. 2008 Nov 11;105(45):17538-42
references: 18981414