title: Recent advances in the phylogenetic study of ghrelin.
abstract: To understand fully the biology of ghrelin, it is important to know the evolutionary history of ghrelin and its receptor. Phylogenetic and comparative genomic studies of mammalian and non-mammalian vertebrates are a useful approach to that end. Ghrelin is a hormone that has apparently evaded natural selection during a long evolutionary history. Surely ghrelin plays crucial physiological roles in living animals. Phylogenetic studies reveal the nature and evolutionary history of this important signaling system.
authors: Department of Biochemistry, National Cerebral and Cardiovascular Center Research Institute, Osaka, Japan. kaiya@ri.ncvc.go.jp
authors: Hiroyuki
authors: H
authors: Kaiya
authors: Mikiya
authors: M
authors: Miyazato
authors: Kenji
authors: K
authors: Kangawa