title: 1-Adamantylmethyl 2-amino-benzoate.
abstract: The asymmetric unit of the title compound, C(18)H(23)NO(2), consists of two crystallographically independent mol-ecules bearing an adamantane cage consisting of three fused cyclo-hexane rings in almost ideal chair conformations, with C-C-C angles in the range 108.47 (16)-110.59 (15)°. Both aryl rings are essentially planar, the maximum deviation from the best plane being 0.0125 (19) Å. One conformer forms chains parallel to the b axis via N-H⋯O hydrogen bonds, whereas the second exhibits only an intra-molecular N-H⋯O hydrogen bond. The crystal structure is stabilized by further weak N-H⋯O and N-H⋯N inter-actions.
authors: Zuzana
authors: Z
authors: Kozubková
authors: Michal
authors: M
authors: Rouchal
authors: Marek
authors: M
authors: Nečas
authors: Robert
authors: R
authors: Vícha
references: Br J Pharmacol. 2005 Jan;144(1):80-7
references: 15644871
references: Acta Crystallogr A. 2008 Jan;64(Pt 1):112-22
references: 18156677
references: Neurotherapeutics. 2009 Jan;6(1):175-86
references: 19110208