title: Anaplastic meningioma with extremely rapid recurrence.
abstract: A 62-year-old woman presented with an uncommon case of anaplastic meningioma manifesting as recent memory disturbance. Magnetic resonance imaging revealed a mass located in the right temporal lobe. She became unconscious because of uncal herniation and underwent urgent surgery. The tumor was completely resected, except for a lesion tightly attached to arteries. Histological examination indicated the presence of anaplastic meningioma with an extremely high MIB-1 labeling index (70%). After 43 days, the patient developed local recurrence and dissemination in the left temporal lobe. The exceptionally high MIB-1 labeling index corresponded with a short tumor doubling time (8.2 days). Whole-brain irradiation and linear accelerator surgery for disseminated lesions were performed, and the tumor growth halted. Although meningiomas rarely show malignant behavior, corresponding to World Health Organization grade III, it is necessary to consider malignant behavior when treating meningiomas.
authors: Department of Neurosurgery, Graduate School of Medical Science, Kanazawa University, Ishikawa.
authors: Yosuke
authors: Y
authors: Kawahara
authors: Mitsutoshi
authors: M
authors: Nakada
authors: Yutaka
authors: Y
authors: Hayashi
authors: Takuya
authors: T
authors: Watanabe
authors: Akira
authors: A
authors: Tamase
authors: Yasuhiko
authors: Y
authors: Hayashi
authors: Naoyuki
authors: N
authors: Uchiyama
authors: Hisashi
authors: H
authors: Nitta
authors: Jun-Ichiro
authors: J
authors: Hamada