title: Photorefractive keratectomy in posterior polymorphous dystrophy with vesicular and band subtypes.
abstract: OBJECTIVE
  To evaluate the safety and efficacy of photorefractive keratectomy (PRK) in patients with posterior polymorphous dystrophy (PPMD) with vesicular and band subtypes.
  
  
  METHODS
  Walter Reed Center for Refractive Surgery, Washington, DC, USA.
  
  
  METHODS
  Case series.
  
  
  METHODS
  The records of patients with PPMD who had PRK between January 2002 and May 2009 were reviewed. Data for analysis included sex, age, ablation depth, residual stromal bed thickness, manifest spherical equivalent, uncorrected (UDVA) and corrected (CDVA) distance visual acuities, central corneal thickness (CCT), endothelial cell density (ECD), intraocular pressure (IOP), and complications. Preoperative and postoperative results were compared using the Wilcoxon signed-rank test, with P < .05 considered significant.
  
  
  RESULTS
  Fourteen eyes of 7 men (mean age 29.1 years ± 9.1 [SD]; range 21 to 42 years) with at least a 6-month follow-up were reviewed. At the final follow-up (mean 19.5 months; range 6.3 to 58.3 months), all eyes had a UDVA of 20/15 and all eyes were within ± 0.50 diopter of emmetropia. The CDVA was unchanged from preoperatively in 71.4% of eyes and improved by 1 line in 28.6%. There were no significant complications. The IOP did not change significantly over the follow-up (P = .272). At the final visit, the mean ECD (2795.3 ± 366.0 cells/mm(2)) was unchanged from baseline (2809.1 ± 338.3 cells/mm(2)) (P = .114).
  
  
  CONCLUSIONS
  Photorefractive keratectomy in PPMD patients with vesicular and band subtypes resulted in excellent visual outcomes and a low incidence of adverse effects. Endothelial cell densities did not change significantly in the early postoperative period.
  
  
  BACKGROUND
  No author has a financial or proprietary interest in any material or method mentioned.
authors: Center for Refractive Surgery, Walter Reed Army Medical Center, Washington, DC, USA.
authors: Kraig S
authors: KS
authors: Bower
authors: Edward W
authors: EW
authors: Trudo
authors: Denise S
authors: DS
authors: Ryan
authors: Rose K
authors: RK
authors: Sia
authors: Michael J
authors: MJ
authors: Mines
authors: Richard D
authors: RD
authors: Stutzman
authors: Keith J
authors: KJ
authors: Wroblewski