title: Comparative study of 6-APA production by free and agar immobilized bacteria in nutrient broth culture.
abstract: In the present study different bacterial samples were isolated from soil of different places of Dibrugarh and screened for biotransformation ability to produce 6-Aminopenicillanic acid. Among ten isolated bacterial samples, three gram positive bacterial samples designated as AKDD-2, AKDD-4 and AKDD-6 showed the production of 6-APA from penicillin G. Assessment of production of 6-APA after incubation in penicillin G (2 mg/ml) by three different samples separately in free and agar immobilization state was done by HPLC analysis. Reusability of immobilized cells was found successful up to 14 days.
authors: Department of Pharmaceutical Sciences, Dibrugarh University, Dibrugarh 786 004, India. ak_dolui@yahoo.com
authors: A K
authors: AK
authors: Dolui
authors: S
authors: S
authors: Das