title: Laparoscopic repair of large hiatal hernia: impact on dyspnoea.
abstract: BACKGROUND
  This study aims to examine the impact of laparoscopic repair of large hiatal hernia on dyspnoea severity, respiratory function and quality of life.
  
  
  METHODS
  From 2004 to 2008, 30 consecutive patients with large para-oesophageal hernia defined as >50% of stomach in the intra-thoracic cavity and minimum follow-up of 2 years were included in this study. All patients had a formal respiratory function test 1 week prior and 3 months after their laparoscopic hiatal hernia repair. Patients rated symptom severity and completed a quality-of-life questionnaire [Gastrointestinal Quality of Life Index (GIQLI)] pre-operatively, and post-operatively at 3 months, 6 months and yearly thereafter.
  
  
  RESULTS
  There was no hospital mortality, and the morbidity rate was 10%. In 26 patients with pre-operative dyspnoea, 22 had complete resolution while the remaining 4 had improvement of dyspnoea severity post-operatively. The mean dyspnoea severity index reduced from 2.4 to 1.3 (P < 0.001). Overall, there was 1%, 3% and 3% post-operative increase in forced expiratory volume in 1 s (FEV1), forced vital capacity (FVC) and diffusing capacity of the lung for carbon monoxide (DLCO) values for the whole group, none of which reached statistical significance. For patients with resolution or improvement of dyspnoea after laparoscopic repair, no significant change of respiratory function parameters was demonstrated. GIQLI score improved from a pre-operative value of 85.7 to 107.9 post-operatively (P < 0.001).
  
  
  CONCLUSIONS
  We failed to show a significant change in post-operative respiratory function despite clearly demonstrated improvement of respiratory symptoms. Alternative explanations for reduction of dyspnoea severity should be sought.
authors.affiliation: Departments of Upper GI Surgery and Endosurgery, Concord Repatriation General Hospital, Sydney, NSW 2139, Australia.
authors.forename: Jacqui C
authors.initials: JC
authors.lastname: Zhu
authors.forename: Guillermo
authors.initials: G
authors.lastname: Becerril
authors.forename: Katy
authors.initials: K
authors.lastname: Marasovic
authors.forename: Alvin J
authors.initials: AJ
authors.lastname: Ing
authors.forename: Gregory L
authors.initials: GL
authors.lastname: Falk
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004417:Dyspnea / Q000209:etiology / Q000503:physiopathology*; D005260:Female; D005541:Forced Expiratory Volume; D006551:Hernia, Hiatal / Q000150:complications / Q000175:diagnosis / Q000601:surgery*; D006801:Humans; D010535:Laparoscopy; D008176:Lung Volume Measurements; D008297:Male; D008875:Middle Aged; D011653:Pulmonary Diffusing Capacity; D014797:Vital Capacity