title: DNAzyme crosslinked hydrogel: a new platform for visual detection of metal ions.
abstract: We propose the use of DNAzyme as a crosslinker of hydrogel to develop a catalytic platform for the sensing of metal ions. The DNAzyme crosslinked hydrogel can undergo gel-sol transition in response to Cu(2+) ions, which enables sensitive visual detection of Cu(2+) by observing the release of pre-trapped AuNPs.
authors.affiliation: State Key Laboratory of Physical Chemistry of Solid Surfaces, Department of Chemical Biology, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, China.
authors.forename: Haoxue
authors.initials: H
authors.lastname: Lin
authors.forename: Yuan
authors.initials: Y
authors.lastname: Zou
authors.forename: Yishun
authors.initials: Y
authors.lastname: Huang
authors.forename: Jie
authors.initials: J
authors.lastname: Chen
authors.forename: Wei Yun
authors.initials: WY
authors.lastname: Zhang
authors.forename: Zhixia
authors.initials: Z
authors.lastname: Zhuang
authors.forename: Gareth
authors.initials: G
authors.lastname: Jenkins
authors.forename: Chaoyong James
authors.initials: CJ
authors.lastname: Yang
mesh_terms: D055162:Biocatalysis; D003300:Copper / Q000737:chemistry; D021881:DNA, Catalytic / Q000378:metabolism*; D006046:Gold / Q000737:chemistry; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate / Q000737:chemistry*; D007477:Ions / Q000737:chemistry; D053768:Metal Nanoparticles / Q000737:chemistry; D008670:Metals / Q000032:analysis*
chemical_list: D021881:DNA, Catalytic; D007477:Ions; D008670:Metals; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate; D006046:Gold; D003300:Copper