title: [Determination of tetrahydrofuran in urine by headspace solid-phase microextraction and gas chromatography].
abstract: OBJECTIVE
  Headspace solid-phase microextraction (HS-SPME) was used pre-concentration procedure for the determination of tetrahydrofuran in urine by gas chromatography with hydrogen flame detector.
  
  
  METHODS
  Several parameters controlling SPME was studied and optimised: SPME fiber, extraction time and extraction temperature, desorption time and desorption temperature.
  
  
  RESULTS
  Under optimal conditions, the correlation coefficient was 0.9998 and good recoveries (range from 93.0% ∼ 100.8%) were achieved, the detection limit was 0.5 µg/L.
  
  
  CONCLUSIONS
  The method can be applied to the determination of trace amount of tetrahydrofuran in urine.
authors.affiliation: Institute of Labour Hygiene and Occupational Diseases of Hunan Province, Changsha, Hunan Province 410007, China.
authors.forename: Zhi-hui
authors.initials: ZH
authors.lastname: Han
authors.forename: Sheng
authors.initials: S
authors.lastname: Fu
authors.forename: Ke-ping
authors.initials: KP
authors.lastname: Yu
mesh_terms: D002849:Chromatography, Gas / Q000379:methods*; D005663:Furans / Q000652:urine*; D006801:Humans; D016273:Occupational Exposure / Q000032:analysis*; D052617:Solid Phase Microextraction / Q000379:methods*
chemical_list: D005663:Furans; C018674:tetrahydrofuran