title: A preliminary study of enamel remineralization by dentifrices based on Recalden (CPP-ACP) and Novamin (calcium-sodium-phosphosilicate).
abstract: The purpose of this study was to investigate the enamel remineralization potential of two toothpastes, one of which was based on Recaldent (CPP- ACP) and the other on NovaMin (Calcium-sodium-phosphosilicate). Human permanent molar teeth were subjected to three consecutive demineralization cycles. These cycles were followed by remineralization of the experimental groups by toothpastes containing Recalden and NovaMin respectively. The samples were analyzed by Scanning Electron Microscope, (SEM) and energy-dispersive X-ray spectroscopy analysis (EDX). Extensive demineralization was noted in the control group (without remineralization) while the groups treated with the dentifices demonstrated various degrees of remineralization, as shown by formation of different types of deposits on the enamel surface. The EDX analysis showed increased amounts of Ca, P Si and Zn in the enamel of the experimental groups, compared to the control one. Toothpastes containing Recalden and especially NovaMin have the potential to remineralize enamel, a property which might be important in finding a substitute to pit and fissure sealing.
authors.affiliation: Faculty of Dental Medicine, Department of Paediatric and Preventive Dentistry, University Ss. Cyril and Methodius Skopje, Republic of Macedonia. elizabetag2000@yahoo.com
authors.forename: Elizabeta S
authors.initials: ES
authors.lastname: Gjorgievska
authors.forename: John W
authors.initials: JW
authors.lastname: Nicholson
mesh_terms: D002118:Calcium / Q000032:analysis; D017610:Calcium Compounds / Q000627:therapeutic use; D002364:Caseins / Q000737:chemistry / Q000627:therapeutic use*; D003743:Dental Enamel / Q000187:drug effects* / Q000648:ultrastructure; D005898:Glass / Q000737:chemistry; D006801:Humans; D008855:Microscopy, Electron, Scanning; D010758:Phosphorus / Q000032:analysis; D017553:Phosphorus Compounds / Q000627:therapeutic use; D017640:Silicates / Q000627:therapeutic use; D012825:Silicon / Q000032:analysis; D013052:Spectrometry, X-Ray Emission; D017001:Tooth Demineralization / Q000628:therapy; D014089:Tooth Remineralization / Q000379:methods*; D014100:Toothpastes / Q000627:therapeutic use; D015032:Zinc / Q000032:analysis
chemical_list: D017610:Calcium Compounds; D002364:Caseins; C510984:NovaMin; D017553:Phosphorus Compounds; D017640:Silicates; D014100:Toothpastes; C447032:casein phosphopeptide-amorphous calcium phosphate nanocomplex; D010758:Phosphorus; C005691:sodium silicate; D015032:Zinc; D002118:Calcium; D012825:Silicon