title: Thyroidectomy with LigaSure.
abstract: OBJECTIVE
  A new method for ensuring hemostasis during thyroid surgery has recently been introduced. This technique, electrothermal (LigaSure) and ultrasound blood vessel sealing, is still experimental. The aim of the present study was to evaluate the applications and efficacy of LigaSure by analyzing the duration of the surgery and the rate of complications of the surgical procedure.
  
  
  METHODS
  A total of 23 patients who underwent the LigaSure operation (n(LS) group) were analyzed in a prospective nonrandomized/partly randomized clinical study, and were compared with patients who underwent treatment using the conventional (ligature) surgical technique.
  
  
  RESULTS
  At our institutions, 187 patients were treated surgically for thyroid disease in 2006, and 23 of these patients were treated using LigaSure. The complication rate in the patients treated with LigaSure (n(LS): 4.3%) was lower than those who received conventional ligature surgery. However, given the small number of patients, this difference was not statistically significant (retrospective group n(1): 10.7%; nonrandomized group n(2): 9.8%; and randomized group n(3): 9.1%). The length of surgery in the LigaSure group (n(LS) = 65 ± 3 min) was significantly shorter (P < 0.001) compared with both nonrandomized (n(2) = 71 ± 6 min) and randomized (n(3) = 70 ± 4 min) patients who received a conventional ligature.
  
  
  CONCLUSIONS
  The application of LigaSure using meticulous surgical technique provides a new option for a safe thyroidectomy. Moreover, the duration of the LigaSure procedure is significantly shorter, and there are fewer complications as compared with the classic surgical thyroidectomy technique.
authors.affiliation: Surgical Clinic, Clinical-Hospital Centre Zvezdara, Nikola Spasić, Dimitrija Tucovića 161, 11000, Belgrade, Serbia.
authors.forename: Mile
authors.initials: M
authors.lastname: Ignjatović
authors.forename: Zoran
authors.initials: Z
authors.lastname: Kostić
mesh_terms: D000328:Adult; D005260:Female; D006488:Hemostasis, Surgical / Q000295:instrumentation; D006489:Hemostatic Techniques; D006801:Humans; D008026:Ligation / Q000295:instrumentation; D008875:Middle Aged; D011446:Prospective Studies; D012189:Retrospective Studies; D013959:Thyroid Diseases / Q000601:surgery*; D013965:Thyroidectomy / Q000009:adverse effects / Q000295:instrumentation*; D013997:Time Factors; D055815:Young Adult