title: Atypical intermediate-grade mediastinal carcinoid. Case presentation.
abstract: BACKGROUND
  Approximately 25% of carcinoid tumors develop in the respiratory system. Neuroendocrine carcinoids represent ~5% of all mediastinal tumors and 1-5% of all intrathoracic neoplasms. They contain numerous neurosecretory granules that synthesize, store and release neurohumoral substances that can induce the carcinoid syndrome.
  
  
  METHODS
  A 21-year-old male presented with a rapidly progressive paraneoplastic syndrome unleashed by an acute urethritis. Two left mediastinal masses were identified and resected. Postoperative evolution has been uneventful during the first year.
  
  
  CONCLUSIONS
  We emphasize the importance of early detection of primary and satellite lesions of these tumors including neurohumoral markers and PET/CT scans as in this case, as well as the participation of a multidisciplinary team.
authors.affiliation: Unidad 406, Servicio de Neumología y Cirugía de Tórax, Hospital General de México, México, D. F., Mexico. miroivo@prodigy.net.mx
authors.forename: Araceli
authors.initials: A
authors.lastname: Carrillo-Muñoz
authors.forename: Melissa
authors.initials: M
authors.lastname: Onofre-Borja
authors.forename: Rafael
authors.initials: R
authors.lastname: Borrego-Borrego
authors.forename: Leonora
authors.initials: L
authors.lastname: Chávez-Mercado
authors.forename: Francisco Pascual
authors.initials: FP
authors.lastname: Navarro-Reynoso
authors.forename: Carlos
authors.initials: C
authors.lastname: Ibarra-Pérez
mesh_terms: D000182:ACTH Syndrome, Ectopic / Q000209:etiology*; D000052:Acanthosis Nigricans / Q000209:etiology; D002276:Carcinoid Tumor / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000601:surgery; D003480:Cushing Syndrome / Q000209:etiology*; D005665:Furosemide / Q000494:pharmacology / Q000627:therapeutic use; D006323:Heart Arrest / Q000209:etiology; D006801:Humans; D008297:Male; D008479:Mediastinal Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000601:surgery; D008548:Melanosis / Q000209:etiology; D010257:Paraneoplastic Syndromes / Q000209:etiology; D049268:Positron-Emission Tomography; D014057:Tomography, X-Ray Computed; D014526:Urethritis / Q000150:complications; D014883:Water-Electrolyte Imbalance / Q000209:etiology*; D055815:Young Adult
chemical_list: D005665:Furosemide