title: Eosinophilic gastrointestinal disorders in infants: a Japanese case series.
abstract: BACKGROUND
  Eosinophilic gastrointestinal disorders (EGIDs) are disorders characterized by primary eosinophil inflammation in the gastrointestinal tract. There are a small number of reports of eosinophil infiltration in gastrointestinal tracts presenting as EGIDs in infants. In this study, we present Japanese cases of EGIDs in infants.
  
  
  METHODS
  Five patients diagnosed with or strongly suspected to have EGIDs in our hospital from 2008 to 2010 were reviewed. Radiographic contrast enema examinations and/or endoscopies were performed in 4 and 3 patients, respectively.
  
  
  RESULTS
  There were patients with eosinophilic colitis (1 suspected and 2 biopsy-proven), a patient who was suspected of having allergic eosinophilic enterocolitis, and a patient with eosinophilic gastroenteritis associated with pediatric hypereosinophilic syndrome.
  
  
  CONCLUSIONS
  The causes and clinical findings of patients with intestinal eosinophil inflammation vary. Therefore, deliberate examination and observation are important for patients with infantile EGID.
authors.affiliation: Division of Allergy and Immunology, Gunma Children's Medical Center, Shibukawa, Japan. yamaday@gcmc.pref.gunma.jp
authors.forename: Yoshiyuki
authors.initials: Y
authors.lastname: Yamada
authors.forename: Akira
authors.initials: A
authors.lastname: Nishi
authors.forename: Yoshifumi
authors.initials: Y
authors.lastname: Ebara
authors.forename: Masahiko
authors.initials: M
authors.lastname: Kato
authors.forename: Hideki
authors.initials: H
authors.lastname: Yamamoto
authors.forename: Hideaki
authors.initials: H
authors.lastname: Morita
authors.forename: Ichiro
authors.initials: I
authors.lastname: Nomura
authors.forename: Kenji
authors.initials: K
authors.lastname: Matsumoto
authors.forename: Junko
authors.initials: J
authors.lastname: Hirato
authors.forename: Shin-itsu
authors.initials: SI
authors.lastname: Hatakeyama
authors.forename: Norio
authors.initials: N
authors.lastname: Suzuki
authors.forename: Yasuhide
authors.initials: Y
authors.lastname: Hayashi
mesh_terms: D003106:Colon / Q000473:pathology; D000013:Congenital Abnormalities / Q000473:pathology; D003251:Constriction, Pathologic / Q000473:pathology; D004485:Eczema / Q000150:complications; D004751:Enteritis / Q000097:blood / Q000150:complications / Q000175:diagnosis / Q000209:etiology / Q000473:pathology / Q000628:therapy; D004802:Eosinophilia / Q000097:blood / Q000150:complications / Q000175:diagnosis / Q000209:etiology / Q000473:pathology / Q000628:therapy; D004804:Eosinophils / Q000473:pathology; D005243:Feces / Q000166:cytology; D005260:Female; D005753:Gastric Mucosa / Q000473:pathology; D005756:Gastritis / Q000097:blood / Q000150:complications / Q000175:diagnosis / Q000209:etiology / Q000473:pathology / Q000628:therapy; D006801:Humans; D017681:Hypereosinophilic Syndrome / Q000097:blood / Q000150:complications / Q000473:pathology; D007073:Immunoglobulin E / Q000097:blood / Q000276:immunology; D007223:Infant; D007231:Infant, Newborn; D007413:Intestinal Mucosa / Q000473:pathology; D007564:Japan; D008297:Male; D016269:Milk Hypersensitivity / Q000150:complications / Q000276:immunology; D009205:Myocarditis / Q000150:complications; D009780:Occult Blood; D011239:Prednisolone / Q000627:therapeutic use; D012007:Rectum / Q000473:pathology; D013577:Syndrome
chemical_list: D007073:Immunoglobulin E; D011239:Prednisolone