title: Self-assembled functional organic monolayers on oxide-free copper.
abstract: The preparation and characterization of self-assembled monolayers on copper with n-alkyl and functional thiols was investigated. Well-ordered monolayers were obtained, while the copper remained oxide-free. Direct attachment of N-succinimidyl mercaptoundecanoate (NHS-MUA) onto the copper surface allowed for the successful attachment of biomolecules, such as β-d-glucosamine, the tripeptide glutathione, and biotin. Notably, the copper surfaces remained oxide-free even after two reaction steps. All monolayers were characterized by static water contact angle measurements, X-ray photoelectron spectroscopy, and infrared reflection absorption spectroscopy. In addition, the biotinylated copper surfaces were employed in the immobilization of biomolecules such as streptavidin.
authors.affiliation: Laboratory of Organic Chemistry, Wageningen University and Research Center, Dreijenplein 8, 6703 HB, Wageningen, The Netherlands.
authors.forename: Mabel A Caipa
authors.initials: MA
authors.lastname: Campos
authors.forename: Anke K
authors.initials: AK
authors.lastname: Trilling
authors.forename: Menglong
authors.initials: M
authors.lastname: Yang
authors.forename: Marcel
authors.initials: M
authors.lastname: Giesbers
authors.forename: Jules
authors.initials: J
authors.lastname: Beekwilder
authors.forename: Jos M J
authors.initials: JM
authors.lastname: Paulusse
authors.forename: Han
authors.initials: H
authors.lastname: Zuilhof
mesh_terms: D000438:Alcohols / Q000737:chemistry*; D002264:Carboxylic Acids / Q000737:chemistry*; D003300:Copper / Q000737:chemistry*; D008567:Membranes, Artificial; D015394:Molecular Structure; D010316:Particle Size; D019809:Streptavidin / Q000737:chemistry; D013388:Succinimides / Q000737:chemistry*; D013438:Sulfhydryl Compounds / Q000737:chemistry*; D013499:Surface Properties
chemical_list: D000438:Alcohols; D002264:Carboxylic Acids; D008567:Membranes, Artificial; D013388:Succinimides; D013438:Sulfhydryl Compounds; D003300:Copper; D019809:Streptavidin; C001426:N-hydroxysuccinimide