title: Ocular oscillations in the neuromyelitis optica spectrum.
abstract: Four French West Indian women complained of oscillopsia and were found to have an acquired eye movement disorder. In 3 of them, different types of nystagmus were found, including upbeat, downbeat, and central form of vestibular nystagmus. One developed opsoclonus-myoclonus syndrome. Three patients had neuromyelitis optica antibodies, and 3 had brainstem abnormalities detected on MRI. Two patients had definite NMO, while the other 2 were considered to be at high risk for developing NMO. Treatment with high-dose systemic corticosteroids, with plasma exchanges, or in combination led to resolution of oscillopsia. We propose that eye movement disorders be added to the neurological manifestations of NMO.
authors.affiliation: Department of Ophthalmology, University Hospital of Fort-de-France, Martinique, French West Indies. rabih.hage@gmail.com
authors.forename: Rabih
authors.initials: R
authors.lastname: Hage
authors.forename: Harold
authors.initials: H
authors.lastname: Merle
authors.forename: Séverine
authors.initials: S
authors.lastname: Jeannin
authors.forename: Philippe
authors.initials: P
authors.lastname: Cabre
mesh_terms: D000328:Adult; D001933:Brain Stem / Q000473:pathology; D005260:Female; D006801:Humans; D008875:Middle Aged; D009471:Neuromyelitis Optica / Q000150:complications* / Q000188:drug therapy / Q000473:pathology*; D009759:Nystagmus, Pathologic / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology*; D015835:Ocular Motility Disorders / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology*; D009900:Optic Nerve / Q000473:pathology; D013116:Spinal Cord / Q000473:pathology; D013577:Syndrome; D016896:Treatment Outcome; D055815:Young Adult