title: Current evidence of antifungal prophylaxis and therapy in pediatric patients.
abstract: Invasive fungal infections (IFI) are an important complication in pediatric haematological and oncological patients who undergo intensive chemotherapy for leukemia, solid tumour at advanced stage or relapsed, and hematopoietic stem cell transplantation. The incidence of IFI is lower than bacterial infection but mortality rate remains high. This review is designed to help paediatric oncologists in choosing the appropriate anti-fungal strategy and agents for prophylaxis, empirical, pre-emptive and specific therapy on the basis of published evidence.
authors.affiliation: Pediatric Hematology Oncology and Bone Marrow Unit, Ospedale Infantile Regina Margherita, Torino;
authors.forename: Mareva
authors.initials: M
authors.lastname: Giacchino
authors.forename: Giuseppe Maria
authors.initials: GM
authors.lastname: Milano
authors.forename: Francesca
authors.initials: F
authors.lastname: Carraro
authors.forename: Stefania
authors.initials: S
authors.lastname: Bezzio
authors.forename: Anna
authors.initials: A
authors.lastname: Pegoraro
authors.forename: Franco
authors.initials: F
authors.lastname: Aversa
authors.forename: Simone
authors.initials: S
authors.lastname: Cesaro