title: Photodynamic therapy for unilateral idiopathic peripapillary choroidal neovascularization in a child.
abstract: A 10-year-old girl presented with visual loss in her right eye. Best-corrected visual acuity was 20/50 in the right eye and 20/20 in the left eye. Dilated funduscopic examination revealed a yellowish elevated lesion near the optic disc with macular edema and hemorrhage on the inferotemporal vascular arcade in the right eye. Fluorescein angiography showed a hyperfluorescent lesion consistent with choroidal neovascularization (CNV) and optical coherence tomography (OCT) showed a peripapillary lesion with subretinal fluid elevating the neurosensory retina in the macular area. With a diagnosis of unilateral idiopathic peripapillary CNV, the patient underwent photodynamic therapy (PDT) with verteporfin. At the four month follow-up, visual acuity increased to 20/25 and OCT showed peripapillary scar formation and total resolution of the subretinal fluid. At the one year follow-up, visual acuity and fundus were stable without recurrence of the lesion. PDT for peripapillary CNV in children has not previously been reported. Although it seems to be a favorable treatment option for peripapillary lesions, there is a lack of knowledge about long-term follow-up in pediatric cases.
authors.affiliation: Department of Ophthalmology, Pamukkale University, Göz Hastalıkları AD, Kınıklı Kampüsü, Kınıklı, Denizli, Turkey. yildirimc@hotmail.com
authors.forename: Cem
authors.initials: C
authors.lastname: Yıldırım
authors.forename: Ebru Nevin
authors.initials: EN
authors.lastname: Çetin
authors.forename: Kemal
authors.initials: K
authors.lastname: Yayla
authors.forename: Avni Murat
authors.initials: AM
authors.lastname: Avunduk
authors.forename: Volkan
authors.initials: V
authors.lastname: Yaylalı
mesh_terms: D002648:Child; D020256:Choroidal Neovascularization / Q000175:diagnosis / Q000188:drug therapy*; D003937:Diagnosis, Differential; D005260:Female; D005451:Fluorescein Angiography; D005500:Follow-Up Studies; D005654:Fundus Oculi; D006801:Humans; D009898:Optic Disk / Q000473:pathology; D010778:Photochemotherapy / Q000379:methods*; D017319:Photosensitizing Agents / Q000627:therapeutic use; D011166:Porphyrins / Q000627:therapeutic use*; D041623:Tomography, Optical Coherence; D000077362:Verteporfin
chemical_list: D017319:Photosensitizing Agents; D011166:Porphyrins; D000077362:Verteporfin