title: Remission of Cushing's disease with growth hormone replacement.
abstract: Treatment of Cushing's disease is often challenging. The success rates are not satisfactory and therapeutic interventions frequently causes hypopituitarism. We present three cases of remitting Cushing's disease complicated with growth hormone deficiency. Surprisingly, growth hormone replacement resulted in complete clinical and laboratory remission of Cushing's disease in these patients. However, one of the patients died of myocardial infarction. Effects of growth hormone on cortisol metabolism are discussed.
authors.affiliation: Yuzuncu Yil University Medical Faculty, Internal medicine Department of Endocrinology and Metabolism, Van, Turkey.
authors.forename: Mustafa
authors.initials: M
authors.lastname: Öztürk
authors.forename: Murat
authors.initials: M
authors.lastname: Atmaca
mesh_terms: D000328:Adult; D005260:Female; D019382:Human Growth Hormone / Q000172:deficiency* / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D047748:Pituitary ACTH Hypersecretion / Q000188:drug therapy*; D012074:Remission Induction; D016896:Treatment Outcome
chemical_list: D019382:Human Growth Hormone