title: Concurrent occurrence of chronic lymphocytic thyroiditis with hypothyroidism and growth hormone deficiency in a Turner's syndrome patient.
abstract: BACKGROUND
  Concurrent deficiencies of three hormones in patients with Turner's syndrome (TS) have rarely been reported. Here, we describe a case of a young girl who had Turner's syndrome with concomitant chronic lymphocytic thyroiditis, growth hormone deficiency, and hypothyroidism with cardiopericarditis.
  
  
  METHODS
  An 11-year-old girl was referred to the outpatient clinic because of short stature, ochriasis, and cardiopalmus. Her ultrasound revealed absence of ovarian tissue. Karyotype examination suggested Turner's syndrome with sex hormone deficiency. She was found to have an abnormal thyroid gland and elevated thyroid stimulating hormone (TSH). A positive thyroid autoantibody titer confirmed the diagnosis of chronic lymphocytic thyroiditis with hypothyroidism. Furthermore, her growth hormone levels were well below normal.
  
  
  METHODS
  A multi-endocrine disorder, i.e., Turner's syndrome with chronic lymphocytic thyroiditis, growth hormone deficiency, and hypothyroidism with cardiopericarditis was diagnosed. Growth hormone and thyroxin substitution therapy was suggested.
authors.affiliation: Department of Pediatrics, Second Hospital of West China, Sichuan University, Chengdu, China.
authors.forename: Wu
authors.initials: W
authors.lastname: Jin
authors.forename: Fa-Xiang
authors.initials: FX
authors.lastname: Cheng
authors.forename: Mei-Sun
authors.initials: MS
authors.lastname: Xiao
authors.forename: Yang
authors.initials: Y
authors.lastname: Fan
authors.forename: Wang
authors.initials: W
authors.lastname: Dong
mesh_terms: D002648:Child; D002869:Chromosome Aberrations; D004393:Dwarfism, Pituitary / Q000150:complications* / Q000175:diagnosis; D005260:Female; D050031:Hashimoto Disease / Q000097:blood / Q000150:complications* / Q000175:diagnosis; D020249:Hormone Replacement Therapy; D006801:Humans; D007037:Hypothyroidism / Q000097:blood / Q000150:complications* / Q000175:diagnosis; D010493:Pericarditis / Q000150:complications / Q000175:diagnosis; D013972:Thyrotropin / Q000097:blood; D014424:Turner Syndrome / Q000150:complications* / Q000175:diagnosis / Q000235:genetics
chemical_list: D013972:Thyrotropin