title: MicroRNA regulated defense responses in Triticum aestivum L. during Puccinia graminis f.sp. tritici infection.
abstract: Plants have evolved diverse mechanism to recognize pathogen attack and triggers defense responses. These defense responses alter host cellular function regulated by endogenous, small, non-coding miRNAs. To understand the mechanism of miRNAs regulated cellular functions during stem rust infection in wheat, we investigated eight different miRNAs viz. miR159, miR164, miR167, miR171, miR444, miR408, miR1129 and miR1138, involved in three different independent cellular defense response to infection. The investigation reveals that at the initiation of disease, accumulation of miRNAs might be playing a key role in hypersensitive response (HR) from host, which diminishes at the maturation stage. This suggests a possible host-fungal synergistic relation leading to susceptibility. Differential expression of these miRNAs in presence and absence of R gene provides a probable explanation of miRNA regulated R gene mediated independent pathways.
authors.affiliation: Division of Biochemistry, Indian Agricultural Research Institute, New Delhi 110012, India.
authors.forename: Om Prakash
authors.initials: OP
authors.lastname: Gupta
authors.forename: Vipin
authors.initials: V
authors.lastname: Permar
authors.forename: Vikas
authors.initials: V
authors.lastname: Koundal
authors.forename: Uday Dhari
authors.initials: UD
authors.lastname: Singh
authors.forename: Shelly
authors.initials: S
authors.lastname: Praveen
mesh_terms: D001487:Basidiomycota / Q000276:immunology*; D018506:Gene Expression Regulation, Plant / Q000276:immunology*; D015723:Gene Library; D035683:MicroRNAs / Q000276:immunology*; D010935:Plant Diseases / Q000276:immunology* / Q000382:microbiology; D010937:Plant Growth Regulators / Q000276:immunology*; D016133:Polymerase Chain Reaction; D015398:Signal Transduction / Q000276:immunology*; D014908:Triticum
chemical_list: D035683:MicroRNAs; D010937:Plant Growth Regulators