title: [Analysis of transporter function and development to clinical application].
authors.affiliation: Division of Nephrology, Endocrinology, and Vascular Medicine, Department of Medicine Tohoku University Hospital, 1-1 Seiryocho, Aoba-ku, Sendai, Miyagi 980-8574, Japan.
authors.forename: Takafumi
authors.initials: T
authors.lastname: Toyohara
authors.forename: Takaaki
authors.initials: T
authors.lastname: Abe
mesh_terms: D000156:Aconitic Acid / Q000378:metabolism; D000818:Animals; D001120:Arginine / Q000031:analogs & derivatives / Q000378:metabolism; D006146:Guanidines / Q000378:metabolism; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000494:pharmacology / Q000627:therapeutic use; D033461:Hyperuricemia / Q000188:drug therapy*; D007668:Kidney / Q000378:metabolism*; D027361:Organic Anion Transporters / Q000378:metabolism / Q000502:physiology* / Q000627:therapeutic use*; D027701:Organic Cation Transport Proteins / Q000627:therapeutic use; D051381:Rats; D051437:Renal Insufficiency / Q000188:drug therapy* / Q000378:metabolism; D013386:Succinates / Q000378:metabolism
chemical_list: D006146:Guanidines; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D027361:Organic Anion Transporters; D027701:Organic Cation Transport Proteins; C491241:SLC22A12 protein, human; C484530:SLCO4C1 protein, human; D013386:Succinates; C001318:guanidinosuccinic acid; C018524:N,N-dimethylarginine; D000156:Aconitic Acid; D001120:Arginine