title: Combining DNA-microarray data in systemic lupus erythematosus.
abstract: Systemic lupus erythematosus is a systemic, heterogeneous autoimmune disease. Understanding of its molecular complexity is incomplete and there is a need to identify new therapeutic targets and to optimize criteria for its diagnosis, assessment and prognosis. Recently, Arasappan and colleagues have described a new meta-analysis method that enables data analysis across different DNA-microarray datasets to identify genes and processes relevant to systemic lupus erythematosus. Their study provides a simple and valuable meta-analysis method for the selection of biomarkers and pathways in disease.See related research by Arasappan et al.: http://www.biomedcentral.com/1741-7015/9/65.
authors.affiliation: Department of Pathology, Section of Inflammatory Disease Profiling, CCA260, VU University Medical Center, 1007 MB Amsterdam, the Netherlands. c.verweij@vumc.nl.
authors.forename: Cornelis L
authors.initials: CL
authors.lastname: Verweij
authors.forename: Saskia
authors.initials: S
authors.lastname: Vosslamber