title: [Polymorphism of connexin 40 gene-- a novel genetic marker of the sick sinus node syndrome].
abstract: In this work we have demonstrated for the first time on the clinico-genetic material association between hereditary sick sinus node syndrome and connexin 40 gene polymorphism. We have revealed that heterozygous variant of connexin 40 gene variant is more frequent among patients with sick sinus node syndrome and their healthy relatives than in persons of control group.
authors.forename: A A
authors.initials: AA
authors.lastname: Chernova
authors.forename: S Iu
authors.initials: SIu
authors.lastname: Nikulina
authors.forename: V A
authors.initials: VA
authors.lastname: Shul'man
authors.forename: T S
authors.initials: TS
authors.lastname: Kukushkina
authors.forename: M I
authors.initials: MI
authors.lastname: Voevoda
authors.forename: V N
authors.initials: VN
authors.lastname: Maksimov
mesh_terms: D000328:Adult; D017630:Connexins / Q000235:genetics*; D005260:Female; D006580:Genetic Carrier Screening; D005819:Genetic Markers; D020022:Genetic Predisposition to Disease; D006801:Humans; D008297:Male; D008875:Middle Aged; D011110:Polymorphism, Genetic; D012804:Sick Sinus Syndrome / Q000235:genetics*; D012849:Sinoatrial Node / Q000002:abnormalities*; D000097003:Gap Junction alpha-5 Protein
chemical_list: D017630:Connexins; D005819:Genetic Markers; D000097003:Gap Junction alpha-5 Protein