title: [Hereditary eye dieseas in the Entlebucher Mountaindog in Switzerland: a retrospective study from 1999 to 2009].
abstract: The aim of this study was to analyze the prevalence and the incidence of hereditary cataract and progressive retinal atrophy (PRA) in the Entlebucher Mountaindog (EMD) and to evaluate possible changes over time. In addition, the influence of selective breeding programs and DNA-testing for PRA was also investigated. Data of eye certifications for hereditary eye diseases was used. Between 1999 and 2009 a total of 798 ocular examinations were carried out in 285 EMD. 20.4 % had cataracts and 69 % of these were of the posterior polar type. PRA was diagnosed in 6.3 % of the dogs. Cataracts were diagnosed at 5.24 ± 2.71 years (mean ± standard error), while PRA was diagnosed at 4.93 ± 1.32 years of age. The incidence of PRA and cataract showed a decreasing trend (p-value > 0.2) without being significant.
authors.affiliation: Departement für Pferde, Abteilung Ophthalmologie der Universität Zürich.
authors.forename: N
authors.initials: N
authors.lastname: Kuster
authors.forename: M
authors.initials: M
authors.lastname: Hässig
authors.forename: B
authors.initials: B
authors.lastname: Spiess
mesh_terms: D000818:Animals; D001947:Breeding; D002386:Cataract / Q000150:complications / Q000453:epidemiology / Q000235:genetics / Q000662:veterinary*; D004283:Dog Diseases / Q000453:epidemiology* / Q000235:genetics; D004285:Dogs; D015785:Eye Diseases, Hereditary / Q000453:epidemiology / Q000235:genetics / Q000662:veterinary*; D005260:Female; D005787:Gene Frequency; D020022:Genetic Predisposition to Disease; D015994:Incidence; D008297:Male; D015995:Prevalence; D012044:Regression Analysis; D012164:Retinal Diseases / Q000150:complications / Q000453:epidemiology / Q000235:genetics / Q000662:veterinary*; D012189:Retrospective Studies; D013557:Switzerland / Q000453:epidemiology; D013997:Time Factors