title: Usefulness of F-18 FDG PET/CT in the evaluation of neck swelling in polymorphic posttransplant lymphoproliferative disorder after renal transplantation.
abstract: A 38-year-old man with a history of renal transplantation presented with a 3-month history of bilateral neck swelling. Ultrasonography of the neck showed multiple enlarged lymph nodes at the bilateral neck. Histologic examination of a specimen from an excisional biopsy at right level II cervical lymph node revealed polymorphic posttransplant lymphoproliferative disorder. F-18 fluorodeoxyglucose (FDG) positron emission tomography/computed tomography scan was performed for further evaluation. The scan revealed marked enlargement and intense hypermetabolism of the lymph nodes along the bilateral cervical lymph node chains (Fig. 1). Several reports have described that diverse infectious or inflammatory disorders and malignant diseases show various degree of FDG uptake of cervical lymph nodes. This case illustrates that the possibility of posttransplant lymphoproliferative disorder should be considered in renal transplant patients with increased FDG uptake of cervical lymph nodes on F-18 FDG positron emission tomography/computed tomography scan.
authors.affiliation: Department of Nuclear Medicine, Keimyung University School of Medicine, Jung-Gu, Daegu, Korea.
authors.forename: Sung Hoon
authors.initials: SH
authors.lastname: Kim
authors.forename: Seok Kil
authors.initials: SK
authors.lastname: Zeon
authors.forename: Byung Wook
authors.initials: BW
authors.lastname: Choi
authors.forename: Hae Won
authors.initials: HW
authors.lastname: Kim
authors.forename: Kyoung Sook
authors.initials: KS
authors.lastname: Won
authors.forename: Su Jin
authors.initials: SJ
authors.lastname: Kim
mesh_terms: D000328:Adult; D019788:Fluorodeoxyglucose F18; D006801:Humans; D007150:Immunohistochemistry; D007249:Inflammation / Q000000981:diagnostic imaging* / Q000209:etiology / Q000473:pathology; D016030:Kidney Transplantation / Q000009:adverse effects*; D008232:Lymphoproliferative Disorders / Q000000981:diagnostic imaging* / Q000209:etiology / Q000473:pathology; D008297:Male; D009333:Neck / Q000000981:diagnostic imaging / Q000473:pathology*; D049268:Positron-Emission Tomography; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography; D051598:Whole Body Imaging
chemical_list: D019788:Fluorodeoxyglucose F18