title: Inorganic nanoparticles for enhanced photodynamic cancer therapy.
abstract: Photodynamic therapy (PDT) in cancer treatment uses photosensitizers to generate singlet oxygen followed by photoirradiation. The efficacy of PDT is greatly determined by the dosimetry of activation light and the photosensitizer (PS), modulating the photodynamic reaction at depth in diseased tissue. Development of nano-formulated photosensitizer has emerged as a promising field because of the biocompatibility and the accessibility for multi-functionalization of nanoparticles. In this review, we summarize the contemporary progress in use of inorganic nanoparticles for improvement of PDT in cancer therapeutics.
authors.affiliation: Division of Medical Engineering Research, National Health Research Institutes, Taiwan.
authors.forename: Shih-Hsun
authors.initials: SH
authors.lastname: Cheng
authors.forename: Leu-Wei
authors.initials: LW
authors.lastname: Lo
mesh_terms: D000818:Animals; D001672:Biocompatible Materials; D016503:Drug Delivery Systems; D006801:Humans; D053758:Nanoparticles; D009369:Neoplasms / Q000188:drug therapy* / Q000473:pathology; D010778:Photochemotherapy / Q000379:methods*; D017319:Photosensitizing Agents / Q000008:administration & dosage / Q000627:therapeutic use
chemical_list: D001672:Biocompatible Materials; D017319:Photosensitizing Agents