title: A chiral perazamacrocyclic fluorescent sensor for cascade recognition of Cu(II) and the unmodified α-amino acids in protic solutions.
abstract: A novel chiral Perazamacrocyclic fluorescent sensor (1) was designed and synthesized. It can serve as a fluorescent turn-off sensor with high selectivity toward Cu(II) among 14 metal ions. Furthermore, though 1 exhibits no enantioselectivity, after adding Cu(II), the in situ generated Cu(II)-containing complex of 1 (Cu(II)-1) can exhibit remarkable fluorescent enhancement responses and considerable enantioselectivities toward unmodified α-amino acids in protic solutions via a ligand displacement mechanism; i.e. a cascade recognition of Cu(II) and unmodified α-amino acids has been achieved.
authors.affiliation: State Key Laboratory of Coordination Chemistry, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, China.
authors.forename: Xia
authors.initials: X
authors.lastname: Yang
authors.forename: Xuechao
authors.initials: X
authors.lastname: Liu
authors.forename: Kang
authors.initials: K
authors.lastname: Shen
authors.forename: Chengjian
authors.initials: C
authors.lastname: Zhu
authors.forename: Yixiang
authors.initials: Y
authors.lastname: Cheng
mesh_terms: D000596:Amino Acids / Q000737:chemistry*; D001372:Aza Compounds / Q000138:chemical synthesis*; D003300:Copper / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000138:chemical synthesis*; D006859:Hydrogen / Q000737:chemistry; D008024:Ligands; D047028:Macrocyclic Compounds / Q000138:chemical synthesis*; D015394:Molecular Structure; D010100:Oxygen / Q000737:chemistry; D012996:Solutions / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D000596:Amino Acids; D001372:Aza Compounds; D005456:Fluorescent Dyes; D008024:Ligands; D047028:Macrocyclic Compounds; D012996:Solutions; D003300:Copper; D006859:Hydrogen; D010100:Oxygen