title: [The curative effects of transmetil on Amanita verna poisoning].
abstract: OBJECTIVE
  To observe the curative effects of transmetil on Amanita verna poisoning.
  
  
  METHODS
  Twelve cases with Amanita verna poisoning were reviewed. The patients were divided into 2 groups according to usage of transmetil: Group A was treated with traditional protocol (gastric lavage, catharsis, rehydration, diuresis, anti-infection and hemodialysis), Group B was treated with traditional protocol combined with transmetil. The liver function changes on the 1st, 3rd, 5th and 7th day after poisoning and the mortality were compared between 2 groups.
  
  
  RESULTS
  Two cases in group A (6 patients) died. The mortality of group A was 33.3%. The AST levels continued to increase on the 3rd and 5th day, but decreased on the 7th day. TBIL continued to increased on the 1st, 3rd, 5th and 7th day. None in group B died. The TBIL level dropped at 7 d 5 patients showed an increase in ALT at 7 d and 3 patients showed a decrease in AST at 7 d.
  
  
  CONCLUSIONS
  Transmetil may play an important role in reducing the mortality of Amanita verna poisoning.
authors.affiliation: Department of Internal Medicine, Guangzhou Municipal Twelfth Peopleps Hospital, Guangzhou, China.
authors.forename: Ling
authors.initials: L
authors.lastname: Wen
authors.forename: Wei-wei
authors.initials: WW
authors.lastname: Liu
authors.forename: Jian-wei
authors.initials: JW
authors.lastname: Huang
authors.forename: Wei
authors.initials: W
authors.lastname: Yu
mesh_terms: D000293:Adolescent; D000328:Adult; D000369:Aged, 80 and over; D000545:Amanita; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009145:Mushroom Poisoning / Q000188:drug therapy*; D012189:Retrospective Studies; D012436:S-Adenosylmethionine / Q000627:therapeutic use*
chemical_list: D012436:S-Adenosylmethionine