title: Optical breast shape capture and finite-element mesh generation for electrical impedance tomography.
abstract: X-ray mammography is the standard for breast cancer screening. The development of alternative imaging modalities is desirable because mammograms expose patients to ionizing radiation. Electrical impedance tomography (EIT) may be used to determine tissue conductivity, a property which is an indicator of cancer presence. EIT is also a low-cost imaging solution and does not involve ionizing radiation. In breast EIT, impedance measurements are made using electrodes placed on the surface of the patient's breast. The complex conductivity of the volume of the breast is estimated by a reconstruction algorithm. EIT reconstruction is a severely ill-posed inverse problem. As a result, noisy instrumentation and incorrect modelling of the electrodes and domain shape produce significant image artefacts. In this paper, we propose a method that has the potential to reduce these errors by accurately modelling the patient breast shape. A 3D hand-held optical scanner is used to acquire the breast geometry and electrode positions. We develop methods for processing the data from the scanner and producing volume meshes accurately matching the breast surface and electrode locations, which can be used for image reconstruction. We demonstrate this method for a plaster breast phantom and a human subject. Using this approach will allow patient-specific finite-element meshes to be generated which has the potential to improve the clinical value of EIT for breast cancer diagnosis.
authors.affiliation: Thayer School of Engineering, Dartmouth College, 8000 Cummings Hall, Hanover, NH 03755, USA. Jeffrey.R.Forsyth@Dartmouth.edu
authors.forename: J
authors.initials: J
authors.lastname: Forsyth
authors.forename: A
authors.initials: A
authors.lastname: Borsic
authors.forename: R J
authors.initials: RJ
authors.lastname: Halter
authors.forename: A
authors.initials: A
authors.lastname: Hartov
authors.forename: K D
authors.initials: KD
authors.lastname: Paulsen
mesh_terms: D000465:Algorithms; D001940:Breast / Q000033:anatomy & histology* / Q000473:pathology; D001943:Breast Neoplasms / Q000473:pathology; D004553:Electric Conductivity; D017097:Electric Impedance; D004566:Electrodes; D020342:Finite Element Analysis; D006801:Humans; D055620:Optical Phenomena; D019047:Phantoms, Imaging; D014054:Tomography