title: Reliability of repeated cognitive assessment of dementia using a brief computerized battery.
abstract: OBJECTIVE
  The aim of this study was to evaluate the short-term stability and reliability of a brief computerized cognitive battery in established dementia types.
  
  
  METHODS
  Patients were administered the computerized battery twice with administrations approximately 2 hours apart, with intervening conventional neuropsychological tests. Patients were classified clinically, via consensus conference, as healthy controls (n = 23), mild cognitive impairment (n = 20), Alzheimer's disease (n = 52), dementia with Lewy Bodies ([DLB], n = 10), or frontotemporal dementia (n = 9).
  
  
  RESULTS
  Minimal practice effects were evident across Cog-State test administrations. Small magnitude improvements were seen across all groups on a working memory task, and healthy controls showed a mild practice effect on the accuracy of associative learning.
  
  
  CONCLUSIONS
  In established dementia, administration of the CogState tasks appears sensitive to cognitive impairment in dementia. Repeat administration also provided acceptable stability and test-retest reliability with minimal practice effects at short test-retest intervals despite intervening cognitive challenges.
authors.affiliation: Neuropsychology Section, Department of Psychiatry, University of Michigan, Ann Arbor, USA. hammersd@med.umich.edu
authors.forename: Dustin
authors.initials: D
authors.lastname: Hammers
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Spurgeon
authors.forename: Kelly
authors.initials: K
authors.lastname: Ryan
authors.forename: Carol
authors.initials: C
authors.lastname: Persad
authors.forename: Judith
authors.initials: J
authors.lastname: Heidebrink
authors.forename: Nancy
authors.initials: N
authors.lastname: Barbas
authors.forename: Roger
authors.initials: R
authors.lastname: Albin
authors.forename: Kirk
authors.initials: K
authors.lastname: Frey
authors.forename: David
authors.initials: D
authors.lastname: Darby
authors.forename: Bruno
authors.initials: B
authors.lastname: Giordani
mesh_terms: D000368:Aged; D000544:Alzheimer Disease / Q000175:diagnosis / Q000523:psychology; D003704:Dementia / Q000175:diagnosis* / Q000523:psychology*; D003936:Diagnosis, Computer-Assisted; D005260:Female; D057180:Frontotemporal Dementia / Q000175:diagnosis / Q000523:psychology; D006801:Humans; D020961:Lewy Body Disease / Q000175:diagnosis / Q000523:psychology; D008297:Male; D008824:Michigan; D008875:Middle Aged; D009483:Neuropsychological Tests / Q000592:standards*; D015203:Reproducibility of Results