title: Spontaneous lesions in aged captive raccoons (Procyon lotor).
abstract: In nature, free-ranging raccoons typically do not live longer than 2 y; most raccoons in the wild die young due to accidents and diseases. Therefore, few data are available regarding lesions associated with advancing age in raccoons. This communication documents the lesions present in raccoons (7 male; 3 female) that were older than 7 y and had been used as breeders at a commercial facility in central Iowa. The most frequent microscopic lesions in these raccoons included accumulation of iron pigment in livers and spleens (10 of 10 animals evaluated), neuroaxonal degeneration in caudal medulla (10 of 10), vascular mineralization (psammoma body) in choroid plexus (9 of 10), myocardial inclusions (7 of 8), and cystic endometrial hyperplasia (2 of 3). Other conditions were seen with less prevalence. Except for the detection of gastritis with bacteria in the gastric mucosa of 1 raccoon, the presence of inflammatory cells in 3 choroid plexuses, and the presence of Lafora bodies in the brain of 1 animal, all conditions observed had previously been reported in raccoons. Surprisingly, islet-cell amyloidosis, previously observed as common incidental finding in older captive raccoons, was not seen in any of the raccoons we examined. Because free-ranging raccoons are distributed over wide geographic areas, their local environment may have considerable influence on the range of spontaneous lesions that would occur in raccoons obtained from a specific location. Therefore, the lesions found in these raccoons from central Iowa may differ from those of other raccoon populations.
authors.affiliation: National Animal Disease Center, Agricultural Research Service, United States Department of Agriculture, Ames, Iowa, USA. ahamir@mdanderson.org
authors.forename: Amir N
authors.initials: AN
authors.lastname: Hamir
mesh_terms: D000375:Aging / Q000473:pathology* / Q000502:physiology; D000818:Animals; D001947:Breeding; D002831:Choroid Plexus / Q000473:pathology* / Q000503:physiopathology; D005260:Female; D006321:Heart / Q000503:physiopathology; D007484:Iowa; D007501:Iron / Q000378:metabolism; D008099:Liver / Q000378:metabolism / Q000473:pathology; D008297:Male; D009206:Myocardium / Q000473:pathology*; D009420:Nervous System / Q000473:pathology* / Q000503:physiopathology; D011821:Raccoons / Q000502:physiology*; D013154:Spleen / Q000378:metabolism / Q000473:pathology
chemical_list: D007501:Iron