title: Cutaneous fusariosis developing in a post-irradiation site.
abstract: Cutaneous fusariosis is an opportunistic mycosis in immunocompromised patients. We present a novel variation of an immunocompromised patient who developed fusariosis in a previously irradiated site. Irradiation led to atrophy, contraction, fibrosis, barrier disruption, and an altered dermal environment in which the infection developed. Significantly, this is the first case report of fusariosis in a previously irradiated site of an immunocompromised patient. Treatment included debridement and voriconazole.
authors.affiliation: Department of Osteopathic Medicine, University Hospitals Richmond Medical Center, Case Western Reserve University, Cleveland, Ohio, USA.
authors.forename: WeiWei
authors.initials: W
authors.lastname: Dai
authors.forename: Jennifer Warner
authors.initials: JW
authors.lastname: Dharamsi
authors.forename: Sameer
authors.initials: S
authors.lastname: Soliman
authors.forename: Carlos
authors.initials: C
authors.lastname: Ricotti
authors.forename: Rita
authors.initials: R
authors.lastname: Gander
authors.forename: Paul
authors.initials: P
authors.lastname: Bergstresser
authors.forename: Joanna
authors.initials: J
authors.lastname: Chan
mesh_terms: D000328:Adult; D003131:Combined Modality Therapy; D016572:Cyclosporine / Q000009:adverse effects / Q000627:therapeutic use; D003646:Debridement; D003881:Dermatomycoses / Q000188:drug therapy / Q000209:etiology* / Q000382:microbiology / Q000601:surgery; D005260:Female; D005670:Fusarium / Q000302:isolation & purification*; D006801:Humans; D016867:Immunocompromised Host; D007166:Immunosuppressive Agents / Q000009:adverse effects; D016030:Kidney Transplantation; D007871:Leg Ulcer / Q000188:drug therapy / Q000209:etiology* / Q000382:microbiology / Q000601:surgery; D008228:Lymphoma, Non-Hodgkin / Q000532:radiotherapy; D009894:Opportunistic Infections / Q000188:drug therapy / Q000209:etiology* / Q000382:microbiology / Q000601:surgery; D011183:Postoperative Complications / Q000209:etiology / Q000382:microbiology; D011241:Prednisone / Q000009:adverse effects / Q000627:therapeutic use; D011743:Pyrimidines / Q000627:therapeutic use; D011855:Radiodermatitis / Q000150:complications*; D011878:Radiotherapy / Q000009:adverse effects*; D012878:Skin Neoplasms / Q000532:radiotherapy; D014230:Triazoles / Q000627:therapeutic use; D065819:Voriconazole
chemical_list: D007166:Immunosuppressive Agents; D011743:Pyrimidines; D014230:Triazoles; D016572:Cyclosporine; D065819:Voriconazole; D011241:Prednisone