title: An unusual pediatric case with neurofibromatosis and systemic lupus erythematosus.
abstract: Neurofibromatosis type 1 (NF1) is a relatively common autosomal dominant disorder affecting mainly ectodermal and mesodermal tissues. It is well known that patients with NF1 have an increased risk of developing benign and malignant tumors, but its association with autoimmune diseases has been rarely reported. Systemic lupus erythematosus is an autoimmune chronic inflammatory disease that has the potential to affect various organ systems. There are four cases with NF1 and SLE reported in the literature up to date. Here, we report a 9-year-old girl presenting with NF1 and SLE, and to our knowledge, this is the first childhood case in the literature.
authors.affiliation: Pediatric Nephrology, Dr Sami Ulus Childrens and Maternity Hospital, Ankara, Turkey. drsare_ozlu@yahoo.com
authors.forename: Sare Gülfem
authors.initials: SG
authors.lastname: Akyüz
authors.forename: Aysun
authors.initials: A
authors.lastname: Çaltik
authors.forename: Mehmet
authors.initials: M
authors.lastname: Bülbül
authors.forename: Özlem
authors.initials: Ö
authors.lastname: Erdoğan
authors.forename: Rahime
authors.initials: R
authors.lastname: Renda
authors.forename: Gülay
authors.initials: G
authors.lastname: Demircin
mesh_terms: D000284:Administration, Oral; D000293:Adolescent; D000328:Adult; D002648:Child; D004334:Drug Administration Schedule; D005260:Female; D005938:Glucocorticoids / Q000008:administration & dosage; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy / Q000276:immunology; D008297:Male; D009456:Neurofibromatosis 1 / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy / Q000276:immunology; D020551:Pulse Therapy, Drug; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D005938:Glucocorticoids; D007166:Immunosuppressive Agents