title: Comparison of corrected QT interval as measured on electroencephalography versus 12-lead electrocardiography in children with a history of syncope.
abstract: Long QT syndrome can present with neurological manifestations, including syncope and seizure-like activity. These patients often receive an initial neurologic evaluation, including electroencephalography (EEG). Our previous retrospective study suggested an increased prevalence of prolonged corrected QT interval (QTc) measured during the EEG of patients with syncope. The aim of the current study is to assess the accuracy of the EEG QTc reading compared with the nonsimultaneous 12-lead electrocardiography (ECG) in children with syncope. Abnormal QTc was defined as ≥450 ms in boys, ≥460 ms in girls. Forty-two children were included. There was no significant correlation between QTc readings in the EEG and ECG. EEG failed to identify 2 children with prolonged QTc in the ECG and overestimated the QTc in 3 children with normal QTc in the ECG. This study suggests that interpretation of the QTc segment during an EEG is limited. Further studies with simultaneous EEG and 12-lead ECG are warranted.
authors.affiliation: Department of Pediatrics, St. Christopher's Hospital for Children, Drexel University College of Medicine, Philadelphia, Pennsylvania 19134, USA.
authors.forename: Shavonne L
authors.initials: SL
authors.lastname: Massey
authors.forename: Marshall S
authors.initials: MS
authors.lastname: Wise
authors.forename: Nandini
authors.initials: N
authors.lastname: Madan
authors.forename: Karen
authors.initials: K
authors.lastname: Carvalho
authors.forename: Divya
authors.initials: D
authors.lastname: Khurana
authors.forename: Agustin
authors.initials: A
authors.lastname: Legido
authors.forename: Ignacio
authors.initials: I
authors.lastname: Valencia
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D004562:Electrocardiography; D004569:Electroencephalography; D005260:Female; D006801:Humans; D008133:Long QT Syndrome / Q000175:diagnosis*; D008297:Male; D013223:Statistics as Topic; D013575:Syncope / Q000175:diagnosis / Q000503:physiopathology*