title: Effects of dietary carbohydrate sources on plasma glucose, insulin and IGF-I levels in multiparous sows.
abstract: Effects of different carbohydrate sources on plasma glucose, insulin and insulin-like growth factor-I (IGF-I) levels were compared to subsequently be able to study effects of insulin-stimulating diets on follicle development in sows. The following feed components were tested in 12 sows during six consecutive test periods of 9.5 days: dextrose (DEX), sucrose (SUC), lactose (LAC), dextrose plus lactose (DL), sucrose plus lactose (SL), dextrose plus sugarbeet pulp (DSBP) and control (CON). On day 2, 5 and 9 of each test period, plasma glucose (only at day 9), insulin and IGF-I profiles were determined. Despite similar glucose profiles for all diets, the postprandial insulin response was higher for DL and SL compared with CON and LAC; the other diets were intermediate. Plasma IGF-I levels were higher in CON, LAC and SL compared with DSBP, but differences were only marginal. It was concluded that dextrose and sucrose have the potential to stimulate fast and high insulin peaks, especially when combined with additional lactose. Despite the high dextrose in the DSBP diet, the insulin response was flattened, probably due to the viscosity of sugarbeet pulp. The results show that modulation of plasma insulin levels by dietary carbohydrates seems possible in anabolic sows, but IGF-I levels are less easily modified.
authors.affiliation: Department of Animal Sciences, Adaptation Physiology Group, Wageningen University, Wageningen, The Netherlands.
authors.forename: J G M
authors.initials: JG
authors.lastname: Wientjes
authors.forename: N M
authors.initials: NM
authors.lastname: Soede
authors.forename: F
authors.initials: F
authors.lastname: Aarsse
authors.forename: B F A
authors.initials: BF
authors.lastname: Laurenssen
authors.forename: R E
authors.initials: RE
authors.lastname: Koopmanschap
authors.forename: H
authors.initials: H
authors.lastname: van den Brand
authors.forename: B
authors.initials: B
authors.lastname: Kemp
mesh_terms: D000821:Animal Feed / Q000032:analysis; D000824:Animal Nutritional Physiological Phenomena; D000818:Animals; D001786:Blood Glucose / Q000187:drug effects*; D018592:Cross-Over Studies; D004032:Diet / Q000662:veterinary; D004040:Dietary Carbohydrates / Q000032:analysis / Q000378:metabolism*; D005260:Female; D005786:Gene Expression Regulation; D007328:Insulin / Q000097:blood*; D007334:Insulin-Like Growth Factor I / Q000235:genetics / Q000378:metabolism*; D010298:Parity; D011247:Pregnancy; D013552:Swine / Q000097:blood*
chemical_list: D001786:Blood Glucose; D004040:Dietary Carbohydrates; D007328:Insulin; D007334:Insulin-Like Growth Factor I