title: Seizure and mental status change after surgery for pelvic organ prolapse.
abstract: The syndrome of inappropriate antidiuretic hormone secretion (SIADH) is a well-documented postoperative complication but infrequently seen after gynecologic procedures. Clinical presentation is often insidious, and neurologic sequelae may be severe, especially in women. We report the first published case of postoperative hyponatremia due to SIADH after vaginal reconstructive surgery. Our patient sustained a tonic-clonic seizure on postoperative day 2 in the setting of profound hyponatremia. Early detection and prompt treatment allowed her to achieve a complete recovery. Familiarity with uncommon complications of vaginal surgery is important. Prompt initiation of treatment can prevent potentially fatal consequences.
authors.affiliation: Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Keck School of Medicine, University of Southern California, 2020 Zonal Ave, IRD 203, Los Angeles, CA 90033, USA. hes_001@usc.edu
authors.forename: Hindi E
authors.initials: HE
authors.lastname: Stohl
authors.forename: Ralph
authors.initials: R
authors.lastname: Daher
authors.forename: Frank
authors.initials: F
authors.lastname: Aguirre
authors.forename: Chi Chiung Grace
authors.initials: CC
authors.lastname: Chen
mesh_terms: D000368:Aged; D005260:Female; D005440:Fluid Therapy; D006801:Humans; D007010:Hyponatremia / Q000150:complications* / Q000175:diagnosis / Q000523:psychology; D007177:Inappropriate ADH Syndrome / Q000150:complications* / Q000175:diagnosis; D056887:Pelvic Organ Prolapse / Q000601:surgery*; D011183:Postoperative Complications / Q000175:diagnosis*; D012640:Seizures / Q000209:etiology* / Q000628:therapy