title: [Giant optic disk melanocytoma complicated with massive intraocular seeding].
abstract: METHODS
  A 33 year-old female with a large, unilateral, dark tumour of the optic disk with a presumed diagnosis of melanocytoma. After a follow-up of nineteen years, the tumour produced massive intraocular seeding with cataract, secondary glaucoma (pigmentary, melanocytomalytic, inflammatory and pupillary seclusion glaucoma) and amaurosis. The eye is enucleated and the pathological examination confirmed the diagnosis.
  
  
  CONCLUSIONS
  Optic disk melanocytoma is a benign stationary tumour. However, sometimes that are to complications, including visual loss. Our case confirms that vitreous seeding is due to tumour necrosis with dissemination of tumoral debris and melanin, which are phagocytized by macrophages and produce an inflammatory reaction, trabecular plugging and ocular hypertension.
authors.affiliation: Cullen Eye Institute, Baylor College of Medicine, Houston, USA. rfont@bcm.tmc.edu
authors.forename: R L
authors.initials: RL
authors.lastname: Font
authors.forename: V
authors.initials: V
authors.lastname: Chaqués-Alepuz
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008545:Melanoma / Q000473:pathology*; D009361:Neoplasm Invasiveness; D009898:Optic Disk; D019574:Optic Nerve Neoplasms / Q000473:pathology*