title: Differential coupling of visual cortex with default or frontal-parietal network based on goals.
abstract: The relationship between top-down enhancement and suppression of sensory cortical activity and large-scale neural networks remains unclear. Functional connectivity analysis of human functional magnetic resonance imaging data revealed that visual cortical areas that selectively process relevant information are functionally connected with the frontal-parietal network, whereas those that process irrelevant information are simultaneously coupled with the default network. This indicates that sensory cortical regions are differentially and dynamically coupled with distinct networks on the basis of task goals.
authors.affiliation: Department of Neurology, Physiology and Psychiatry, W.M. Keck Foundation Center for Integrative Neuroscience, University of California, San Francisco, USA.
authors.forename: James Z
authors.initials: JZ
authors.lastname: Chadick
authors.forename: Adam
authors.initials: A
authors.lastname: Gazzaley
mesh_terms: D000293:Adolescent; D000328:Adult; D000704:Analysis of Variance; D001931:Brain Mapping; D005260:Female; D005625:Frontal Lobe / Q000098:blood supply / Q000502:physiology*; D006040:Goals; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D008570:Memory, Short-Term / Q000502:physiology; D009462:Neurology / Q000379:methods; D010100:Oxygen / Q000097:blood; D010296:Parietal Lobe / Q000098:blood supply / Q000502:physiology*; D010364:Pattern Recognition, Visual / Q000502:physiology; D010775:Photic Stimulation / Q000379:methods; D011930:Reaction Time; D013997:Time Factors; D014793:Visual Cortex / Q000098:blood supply / Q000502:physiology*; D014795:Visual Pathways / Q000098:blood supply / Q000502:physiology; D055815:Young Adult
chemical_list: D010100:Oxygen