title: Synthesis of 3-substituted indazoles from arynes and N-tosylhydrazones.
abstract: Readily available, stable, and inexpensive N-tosylhydrazones react with arynes under mild reaction conditions to afford 3-substituted indazoles in moderate to good yields. The reaction appears to involve a dipolar cycloaddition of in situ generated diazo compounds and arynes.
authors.affiliation: Key Laboratory of Natural Medicine and Immuno-Engineering of Henan Province, Henan University, Jinming Campus, Kaifeng, 475004, PR China.
authors.forename: Pan
authors.initials: P
authors.lastname: Li
authors.forename: Jingjing
authors.initials: J
authors.lastname: Zhao
authors.forename: Chunrui
authors.initials: C
authors.lastname: Wu
authors.forename: Richard C
authors.initials: RC
authors.lastname: Larock
authors.forename: Feng
authors.initials: F
authors.lastname: Shi
mesh_terms: D006835:Hydrazones / Q000737:chemistry*; D007191:Indazoles / Q000138:chemical synthesis*; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D006835:Hydrazones; D007191:Indazoles