title: [A study of the usefulness of pancreatic juice cytology obtained via an endoscopic nasal pancreatic drainage (ENPD) tube].
abstract: We studied the usefulness of pancreatic juice cytology obtained via an indwelling endoscopic nasal pancreatic drainage (ENPD) tube. In general, cytology was performed three times. The sensitivity was 0.35 on the first time and 0.59 after three times (p<0.01). The sensitivity in relation to tumor size of pancreatic cancer was 0.77 for Tis (3 cases) and TS1 (10 cases), 0.76 for TS2 (29 cases), 0.56 for TS3 (9 cases) and 0 for TS4 (4 cases). A significant difference of p=0.01 was recognized among the 4 groups, and the sensitivity for small tumors was higher than that for large tumors. The pancreatic juice can be obtained repeatedly via the ENPD tube and that contributes to improving the diagnostic accuracy. It is useful as a definitive diagnosis method in early stage pancreatic cancer because it is easier to detect positive results in smaller tumor, furthermore, it is possible to diagnose carcinoma in situ.
authors.affiliation: Department of Gastroenterology, Hiroshima Red Cross & Atomic-bomb Survivors Hospital.
authors.forename: Hirokazu
authors.initials: H
authors.lastname: Kimura
authors.forename: Yoshinari
authors.initials: Y
authors.lastname: Furukawa
authors.forename: Soichiro
authors.initials: S
authors.lastname: Yamasaki
authors.forename: Koichi
authors.initials: K
authors.lastname: Kagawa
authors.forename: Ayaka
authors.initials: A
authors.lastname: Sakano
authors.forename: Mutsumi
authors.initials: M
authors.lastname: Hananoki
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Kurushima
authors.forename: Nori
authors.initials: N
authors.lastname: Matsumoto
authors.forename: Masahiro
authors.initials: M
authors.lastname: Yamamoto
authors.forename: Eiji
authors.initials: E
authors.lastname: Tsujita
authors.forename: Yoichi
authors.initials: Y
authors.lastname: Yamashita
authors.forename: Megumu
authors.initials: M
authors.lastname: Fujiwara
mesh_terms: D000368:Aged; D003581:Cytodiagnosis / Q000379:methods; D004322:Drainage / Q000379:methods; D016145:Endoscopy, Digestive System / Q000379:methods; D005260:Female; D006801:Humans; D008297:Male; D010189:Pancreatic Juice / Q000166:cytology*; D010190:Pancreatic Neoplasms / Q000473:pathology*; D012680:Sensitivity and Specificity