title: Assessment of narrow angles by gonioscopy, Van Herick method and anterior segment optical coherence tomography.
abstract: OBJECTIVE
  To evaluate anterior chamber (AC) angles using gonioscopy, Van Herick technique and anterior segment optical coherence tomography (AS-OCT).
  
  
  METHODS
  One hundred forty-eight consecutive subjects were enrolled. The agreement between any two of three diagnostic methods, gonioscopy, AS-OCT and Van Herick, was calculated in narrow-angle patients. The area under receiver-operating characteristic curves (AUC) for discriminating between narrow and open angles determined by gonioscopy was calculated in all participants for AS-OCT parameter angle opening distance (AOD), angle recess area, trabecular iris surface area and anterior chamber depth (ACD). As a subgroup analysis, capability of AS-OCT parameters for detecting angle closure defined by AS-OCT was assessed in narrow-angle patients.
  
  
  RESULTS
  The agreement between the Van Herick method and gonioscopy in detecting angle closure was excellent in narrow angles (κ = 0.80, temporal; κ = 0.82, nasal). However, agreement between gonioscopy and AS-OCT and between the Van Herick method and AS-OCT was poor (κ = 0.11-0.16). Discrimination capability of AS-OCT parameters between open and narrow angles determined by gonioscopy was excellent for all AS-OCT parameters (AUC, temporal: AOD500 = 0.96, nasal: AOD500 = 0.99). The AUCs for detecting angle closure defined by AS-OCT image in narrow angle subjects was good for all AS-OCT parameters (AUC, 0.80-0.94) except for ACD (temporal: ACD = 0.70, nasal: ACD = 0.63).
  
  
  CONCLUSIONS
  Assessment of narrow angles by gonioscopy and the Van Herick technique showed good agreement, but both measurements revealed poor agreement with AS-OCT. The angle closure detection capability of AS-OCT parameters was excellent; however, it was slightly lower in ACD.
authors.affiliation: BS Eye Center, Seoul, Republic of Korea.|Department of Ophthalmology, College of Medicine, University of Ulsan, Asan Medical Center, 388-1 Pungnap-2-dong, Songpa-gu, Seoul, 138-736, Republic of Korea.
authors.forename: Seong Bae
authors.initials: SB
authors.lastname: Park
authors.affiliation: BS Eye Center, Seoul, Republic of Korea.|Department of Ophthalmology, College of Medicine, University of Ulsan, Asan Medical Center, 388-1 Pungnap-2-dong, Songpa-gu, Seoul, 138-736, Republic of Korea.
authors.forename: Kyung Rim
authors.initials: KR
authors.lastname: Sung
authors.affiliation: BS Eye Center, Seoul, Republic of Korea.|Department of Ophthalmology, College of Medicine, University of Ulsan, Asan Medical Center, 388-1 Pungnap-2-dong, Songpa-gu, Seoul, 138-736, Republic of Korea.
authors.forename: Sung Yung
authors.initials: SY
authors.lastname: Kang
authors.affiliation: BS Eye Center, Seoul, Republic of Korea.|Department of Ophthalmology, College of Medicine, University of Ulsan, Asan Medical Center, 388-1 Pungnap-2-dong, Songpa-gu, Seoul, 138-736, Republic of Korea.
authors.forename: Jung Woo
authors.initials: JW
authors.lastname: Jo
authors.affiliation: BS Eye Center, Seoul, Republic of Korea.|Department of Ophthalmology, College of Medicine, University of Ulsan, Asan Medical Center, 388-1 Pungnap-2-dong, Songpa-gu, Seoul, 138-736, Republic of Korea.
authors.forename: Kyoung Sub
authors.initials: KS
authors.lastname: Lee
authors.affiliation: BS Eye Center, Seoul, Republic of Korea. mskook@amc.seoul.kr.|Department of Ophthalmology, College of Medicine, University of Ulsan, Asan Medical Center, 388-1 Pungnap-2-dong, Songpa-gu, Seoul, 138-736, Republic of Korea. mskook@amc.seoul.kr.
authors.forename: Michael S
authors.initials: MS
authors.lastname: Kook
mesh_terms: D000368:Aged; D000869:Anterior Eye Segment / Q000473:pathology*; D019540:Area Under Curve; D003941:Diagnostic Techniques, Ophthalmological; D005260:Female; D015812:Glaucoma, Angle-Closure / Q000175:diagnosis*; D005902:Glaucoma, Open-Angle / Q000175:diagnosis; D006068:Gonioscopy / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D012372:ROC Curve; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D041623:Tomography, Optical Coherence / Q000379:methods*