title: Taking HSCs down a Notch in leukemia.
abstract: The Notch signaling pathway is activated in the majority of T cell acute lymphoblastic leukemias (T-ALL). Adding to the complexity of Notch signaling in hematopoiesis, recently in Nature, Klinakis et al. (2011) demonstrate a tumor-suppressor function for the Notch pathway in myeloid malignancy.
authors.affiliation: St. Vincent's Institute of Medical Research and Department of Medicine, St. Vincent's Hospital, University of Melbourne, Fitzroy, VIC 3065, Australia.
authors.forename: Carl R
authors.initials: CR
authors.lastname: Walkley
authors.forename: David J
authors.initials: DJ
authors.lastname: Izon
authors.forename: Louise E
authors.initials: LE
authors.lastname: Purton