title: Synthesis of positively charged CdTe quantum dots and detection for uric acid.
abstract: The CdTe dots (QDs) coated with 2-Mercaptoethylamine was prepared in aqueous solution and characterized with fluorescence spectroscopy, UV-Vis absorption spectra, high-resolution transmission electron microscopy and infrared spectroscopy. When the λex=350 nm, the fluorescence peak of positively charged CdTe quantum dots is at 592 nm. The uric acid is able to quench their fluorescence. Under optimum conditions, the change of fluorescence intensity is linearly proportional to the concentration of uric acid in the range 0.4000-3.600 μmol L(-1), and the limit of detection calculated according to IUPAC definitions is 0.1030 μmol L(-1). Compared with routine method, the present method determines uric acid in human serum with satisfactory results. The mechanism of this strategy is due to the interaction of the tautomeric keto/hydroxyl group of uric acid and the amino group coated at the CdTe QDs.
authors.affiliation: College of Material Science and Engineering, The Key Laboratory of Functional Materials for Fujian Higher Education, Huaqiao University, Xiamen 361021, PR China.
authors.forename: Tiliang
authors.initials: T
authors.lastname: Zhang
authors.forename: Xiangying
authors.initials: X
authors.lastname: Sun
authors.forename: Bin
authors.initials: B
authors.lastname: Liu
mesh_terms: D019187:Cadmium Compounds / Q000737:chemistry*; D003543:Cysteamine / Q000737:chemistry*; D006801:Humans; D046529:Microscopy, Electron, Transmission; D045663:Quantum Dots; D013050:Spectrometry, Fluorescence; D013691:Tellurium / Q000737:chemistry*; D014527:Uric Acid / Q000097:blood*
chemical_list: D019187:Cadmium Compounds; D014527:Uric Acid; D003543:Cysteamine; D013691:Tellurium; C028337:cadmium telluride