title: Drimane sesquiterpenoids from the mangrove-derived fungus Aspergillus ustus.
abstract: Five new drimane sesquiterpenes (1-5) together with 14 known analogues (6-19) were isolated from laboratory cultures of a mangrove-derived fungus Aspergillus ustus. Their structures were established by spectroscopic methods and antitumor activities were evaluated by sulforhodamine B (SRB) and 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) methods.
authors.affiliation: Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, P.R. China.
authors.forename: Huinan
authors.initials: H
authors.lastname: Zhou
authors.forename: Tianjiao
authors.initials: T
authors.lastname: Zhu
authors.forename: Shengxin
authors.initials: S
authors.lastname: Cai
authors.forename: Qianqun
authors.initials: Q
authors.lastname: Gu
authors.forename: Dehai
authors.initials: D
authors.lastname: Li
mesh_terms: D000970:Antineoplastic Agents / Q000737:chemistry* / Q000302:isolation & purification / Q000633:toxicity; D001230:Aspergillus / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D000081223:Polycyclic Sesquiterpenes; D012717:Sesquiterpenes / Q000737:chemistry* / Q000302:isolation & purification / Q000633:toxicity
chemical_list: D000970:Antineoplastic Agents; D000081223:Polycyclic Sesquiterpenes; D012717:Sesquiterpenes; C437376:drimane