title: A magnetically active microfluidic device for chemiluminescence bioassays.
abstract: Highly active horseradish peroxidase functionalized magnetic nanoparticles were prepared and packed into a microfluidic channel, producing an in-line bioreactor that enabled a sensitive chemiluminescence assay of H(2)O(2). The proposed magnetically active microfluidic device proved useful for chemiluminescence assays of biomedically interesting compounds.
authors.affiliation: Department of Chemistry and Biochemistry, Jackson State University, 1400 Lynch St., Jackson, MS 39217, USA.
authors.forename: Yi
authors.initials: Y
authors.lastname: Zheng
authors.forename: Shulin
authors.initials: S
authors.lastname: Zhao
authors.forename: Yi-Ming
authors.initials: YM
authors.lastname: Liu
mesh_terms: D019149:Bioreactors; D004800:Enzymes, Immobilized / Q000737:chemistry / Q000378:metabolism; D005947:Glucose / Q000032:analysis; D005949:Glucose Oxidase / Q000737:chemistry / Q000378:metabolism; D006735:Horseradish Peroxidase / Q000737:chemistry / Q000378:metabolism; D006861:Hydrogen Peroxide / Q000032:analysis; D008163:Luminescent Measurements / Q000379:methods*; D058185:Magnetite Nanoparticles / Q000737:chemistry*; D046210:Microfluidic Analytical Techniques / Q000295:instrumentation / Q000379:methods*
chemical_list: D004800:Enzymes, Immobilized; D058185:Magnetite Nanoparticles; D006861:Hydrogen Peroxide; D005949:Glucose Oxidase; D006735:Horseradish Peroxidase; D005947:Glucose