title: Antioxidant dialytic approach with vitamin E-coated membranes.
abstract: Oxidative stress is prevalent in dialysis patients and has been implicated in the pathogenesis of anemia and cardiovascular disease. Vitamin E-coated membranes are low-flux dialyzers consisting of a multilayer membrane with liposoluble vitamin E on the blood surface allowing direct contact with free oxygen radicals to be scavenged on the membrane site. The antioxidant properties of these membranes have an important clinical benefit because of reducing oxygen stress and inflammation may contribute to an improvement of hemoglobin levels, lower recombinant human erythropoietin dose and better anemia management, and at the same time may have a favorable impact on cardiovascular complications.
authors.forename: Anthi
authors.initials: A
authors.lastname: Panagiotou
authors.forename: Federico
authors.initials: F
authors.lastname: Nalesso
authors.forename: Monica
authors.initials: M
authors.lastname: Zanella
authors.forename: Alessandra
authors.initials: A
authors.lastname: Brendolan
authors.forename: Massimo
authors.initials: M
authors.lastname: de Cal
authors.forename: Dinna
authors.initials: D
authors.lastname: Cruz
authors.forename: Flavio
authors.initials: F
authors.lastname: Basso
authors.forename: Matteo
authors.initials: M
authors.lastname: Floris
authors.forename: Anna
authors.initials: A
authors.lastname: Clementi
authors.forename: Claudio
authors.initials: C
authors.lastname: Ronco
mesh_terms: D000975:Antioxidants / Q000494:pharmacology*; D006801:Humans; D008567:Membranes, Artificial; D018384:Oxidative Stress; D006435:Renal Dialysis / Q000379:methods*; D014810:Vitamin E / Q000494:pharmacology*
chemical_list: D000975:Antioxidants; D008567:Membranes, Artificial; D014810:Vitamin E