title: [Clinical characteristics and outcome of 32 patients with long-QT syndrome accompanied with torsade de pointes].
abstract: OBJECTIVE
  To summarize the clinical characteristics and outcome of patients with long-QT syndrome (LQTs) accompanied with torsade de pointes.
  
  
  METHODS
  Thirty-two eligible patients were included in this study. Clinical and electrocardiographic data were analyzed and telephone or out-patient follow-up were made in all patients.
  
  
  RESULTS
  There were 15 patients with inherited LQTs (h-LQTs) and 17 patients with acquired LQTs (a-LQTs). There are more women (n = 24) than men (n = 8). β blockers, potassium and magnesium supplement were the basic therapy for h-LQTs patients, bivent pacemaker was implanted in 2 patients and implantable cardioverter defibrillator was implanted in 5 patients. Ventricular tachyarrhythmias and syncope occurred in 4 patients during (39.4 ± 25.1) months follow-up. In 17 a-LQTs patients, one patient with dilated cardiomyopathy died suddenly and another patient with implanted cardioverter defibrillator experienced one ventricular tachycardia during (30.9 ± 13.3) months follow-up.
  
  
  CONCLUSIONS
  The prognosis in h-LQTs and a-LQTs patients with structure heart disease is poor. ICD or CRT-D therapy is suggestive for a-LQTs patients with structure heart disease.
authors.affiliation: Center for Arrhythmia Diagnosis and Treatment, Cardiovascular Institute and Fu Wai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China.
authors.forename: Cui-hong
authors.initials: CH
authors.lastname: Hou
authors.forename: Jing-tao
authors.initials: JT
authors.lastname: Zhang
authors.forename: Xiao-xing
authors.initials: XX
authors.lastname: Zhang
authors.forename: Ke-ping
authors.initials: KP
authors.lastname: Chen
authors.forename: Wei
authors.initials: W
authors.lastname: Hua
authors.forename: Shu
authors.initials: S
authors.lastname: Zhang
authors.forename: Jie-lin
authors.initials: JL
authors.lastname: Pu
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008133:Long QT Syndrome / Q000150:complications / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D010138:Pacemaker, Artificial; D016171:Torsades de Pointes / Q000150:complications / Q000628:therapy*; D016896:Treatment Outcome; D055815:Young Adult