title: Case report on the development of a brucellosis-related epidural abscess.
abstract: Brucellosis is an endemic disease in developing countries. The most commonly observed complications include bone-joint involvement, particularly sacroiliitis and spondylitis. Epidural abscesses caused by brucellosis are a rare complication. We describe the case of a 33-year-old man presenting with high fever, back pain, and weakness. At physical examination, the patient was found to be paraparetic. At thoracic MRI, spondylodiscitis and epidural abscess with significant cord compression were observed. In laboratory examinations, Rose Bengal and tube agglutination tests were positive in patient's serum for brucellosis, and specific antibiotherapy was initiated. Total laminectomy was performed and the abscess was aspirated. The biopsy sample was consistent with chronic non-specific inflammation in acute abscess. No growth was detected in the abscess or blood cultures. Following surgery, medical treatment was initiated and, at six weeks' follow-up, clinical and MRI findings indicated that he had recovered. The diagnosis of spinal epidural abscess due to brucellosis should be considered among differential diagnoses in endemic regions. Early diagnosis and specific treatment are important to prevent later complications.
authors.affiliation: Infectious Diseases and Clinical Microbiology Clinic, Tepecik Education and Research Hospital, Izmir, Turkey.
authors.forename: Şükran
authors.initials: Ş
authors.lastname: Köse
authors.forename: Süheyla Serin
authors.initials: SS
authors.lastname: Senger
authors.forename: Gülsün
authors.initials: G
authors.lastname: Çavdar
authors.forename: Sibel
authors.initials: S
authors.lastname: Yavaş
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002006:Brucellosis / Q000150:complications* / Q000175:diagnosis* / Q000382:microbiology / Q000473:pathology; D003646:Debridement; D015299:Discitis / Q000175:diagnosis / Q000473:pathology; D020802:Epidural Abscess / Q000175:diagnosis* / Q000382:microbiology / Q000473:pathology* / Q000628:therapy; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D013902:Radiography, Thoracic; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents