title: [Protein C deficiency in black African with venous thromboembolism in Cotonou, Benin].
abstract: The aim of this study is to evaluate the frequency of protein C deficiency in venous thromboembolism in black African patients of Benin. It is a descriptive study. Inclusion criteria were: acceptance- having a venous thromboembolism. No exlusion criteria was retained. Protein C deficiency was diagnosed by quantitative technic with a Minividas materiel in the blood. Protein C dosage has been done before antivitamin k therapy and a second dosage has been done if the first one demonstrated a low level of protein C. Acuired aetiology have been research. For the 54 patients of this study mean age was 52.7±14.1 and sex-ratio 1.08. The frequency of protein C deficiency was 9.3% in all patients and 12.5% in those with clinical thrombophily (p=1). No acquired deficit has been found.
authors.affiliation: Faculté des sciences de la Santé, BP 188, Cotonou, Bénin. houenassi_m@yahoo.fr
authors.forename: D M
authors.initials: DM
authors.lastname: Houénassi
authors.forename: A
authors.initials: A
authors.lastname: Bigot
authors.forename: Y
authors.initials: Y
authors.lastname: Tchabi
authors.forename: J
authors.initials: J
authors.lastname: Vehounkpé-Sacca
authors.forename: R
authors.initials: R
authors.lastname: Akindes-Dossou Yovo
authors.forename: L
authors.initials: L
authors.lastname: Gbaguidi
authors.forename: M
authors.initials: M
authors.lastname: d'Almeida-Massougbodji
authors.forename: H
authors.initials: H
authors.lastname: Agboton
mesh_terms: D000328:Adult; D000368:Aged; D001541:Benin; D044383:Black People; D003430:Cross-Sectional Studies; D003906:Developing Countries; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D020151:Protein C Deficiency / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology / Q000208:ethnology*; D012307:Risk Factors; D054556:Venous Thromboembolism / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology / Q000208:ethnology*; D014812:Vitamin K / Q000037:antagonists & inhibitors
chemical_list: D014812:Vitamin K