title: LinkinPath: from sequence to interconnected pathway.
abstract: CONCLUSIONS
  LinkinPath is a pathway mapping and analysis tool that enables users to explore and visualize the list of gene/protein sequences through various Flash-driven interactive web interfaces including KEGG pathway maps, functional composition maps (TreeMaps), molecular interaction/reaction networks and pathway-to-pathway networks. Users can submit single or multiple datasets of gene/protein sequences to LinkinPath to (i) determine the co-occurrence and co-absence of genes/proteins on animated KEGG pathway maps; (ii) compare functional compositions within and among the datasets using TreeMaps; (iii) analyze the statistically enriched pathways across the datasets; (iv) build the pathway-to-pathway networks for each dataset; (v) explore potential interaction/reaction paths between pathways; and (vi) identify common pathway-to-pathway networks across the datasets.
  
  
  BACKGROUND
  LinkinPath is freely available to all interested users at http://www.biotec.or.th/isl/linkinpath/.
authors.affiliation: Information Systems Laboratory, Bioresources Technology Unit, National Center for Genetic Engineering and Biotechnology, Klong Luang, Pathumthani 12120, Thailand. supawadee@biotec.or.th
authors.forename: Supawadee
authors.initials: S
authors.lastname: Ingsriswang
authors.forename: Sunai
authors.initials: S
authors.lastname: Yokwai
authors.forename: Duangdao
authors.initials: D
authors.lastname: Wichadakul
mesh_terms: D002874:Chromosome Mapping; D053263:Gene Regulatory Networks; D005796:Genes; D020407:Internet; D053858:Metabolic Networks and Pathways; D025941:Protein Interaction Mapping; D011506:Proteins; D017422:Sequence Analysis, DNA / Q000379:methods*; D020539:Sequence Analysis, Protein / Q000379:methods*; D012984:Software
chemical_list: D011506:Proteins