title: Uptake of antioxidants by natural nutrition and supplementation: pros and cons from the dermatological point of view.
abstract: The pros and cons of the systemic and topical application of antioxidant substances are a subject of intense discussion among experts, with resulting confusion for consumers and producers. The objective of the present article is to clarify the various uncertainties relating to the use of antioxidant substances in dermatology. Whereas inappropriate application of antioxidant substances (concerning their concentration and composition) might induce harmful effects, the consumer will definitively benefit from physiological concentrations and compositions of antioxidants. The most suitable method is the consumption of natural antioxidants in the form of fruit and vegetables, for example. In addition, the skin, which also accumulates antioxidant substances, may profit from a sufficient antioxidative level, as damage induced by sun radiation in addition to skin aging is reduced.
authors.affiliation: Center of Experimental and Applied Cutaneous Physiology, Department of Dermatology and Allergology, Charité - Universitätsmedizin Berlin, Germany.
authors.forename: J
authors.initials: J
authors.lastname: Lademann
authors.forename: A
authors.initials: A
authors.lastname: Patzelt
authors.forename: S
authors.initials: S
authors.lastname: Schanzer
authors.forename: H
authors.initials: H
authors.lastname: Richter
authors.forename: M C
authors.initials: MC
authors.lastname: Meinke
authors.forename: W
authors.initials: W
authors.lastname: Sterry
authors.forename: L
authors.initials: L
authors.lastname: Zastrow
authors.forename: O
authors.initials: O
authors.lastname: Doucet
authors.forename: T
authors.initials: T
authors.lastname: Vergou
authors.forename: M E
authors.initials: ME
authors.lastname: Darvin
mesh_terms: D000287:Administration, Topical; D000975:Antioxidants / Q000008:administration & dosage* / Q000494:pharmacology; D005638:Fruit; D006801:Humans; D018384:Oxidative Stress / Q000187:drug effects*; D012867:Skin / Q000187:drug effects*; D015595:Skin Aging / Q000187:drug effects*; D014675:Vegetables
chemical_list: D000975:Antioxidants