title: Efficient bifunctional gallium-68 chelators for positron emission tomography: tris(hydroxypyridinone) ligands.
abstract: A new tripodal tris(hydroxypyridinone) bifunctional chelator for gallium allows easy production of (68)Ga-labelled proteins rapidly under mild conditions in high yields at exceptionally high specific activity and low concentration.
authors.affiliation: King's College London, Division of Imaging Sciences and Biomedical Engineering, The Rayne Institute, St Thomas' Hospital, London, SE1 7EH, UK.
authors.forename: David J
authors.initials: DJ
authors.lastname: Berry
authors.forename: Yongmin
authors.initials: Y
authors.lastname: Ma
authors.forename: James R
authors.initials: JR
authors.lastname: Ballinger
authors.forename: Richard
authors.initials: R
authors.lastname: Tavaré
authors.forename: Alexander
authors.initials: A
authors.lastname: Koers
authors.forename: Kavitha
authors.initials: K
authors.lastname: Sunassee
authors.forename: Tao
authors.initials: T
authors.lastname: Zhou
authors.forename: Saima
authors.initials: S
authors.lastname: Nawaz
authors.forename: Gregory E D
authors.initials: GE
authors.lastname: Mullen
authors.forename: Robert C
authors.initials: RC
authors.lastname: Hider
authors.forename: Philip J
authors.initials: PJ
authors.lastname: Blower
mesh_terms: D000818:Animals; D002614:Chelating Agents / Q000737:chemistry*; D003432:Cross-Linking Reagents / Q000737:chemistry*; D005710:Gallium Radioisotopes; D006801:Humans; D008024:Ligands; D051379:Mice; D049268:Positron-Emission Tomography / Q000379:methods*; D011728:Pyridones / Q000737:chemistry*; D050863:Synaptotagmin I / Q000737:chemistry
chemical_list: D002614:Chelating Agents; D003432:Cross-Linking Reagents; D005710:Gallium Radioisotopes; D008024:Ligands; D011728:Pyridones; D050863:Synaptotagmin I