title: Pulmonary langerhans cell histiocytosis with recurrent pneumothorax.
abstract: A 20-year-old woman with recurrent right pneumothorax was admitted to our hospital. A thoracoscopic bullectomy and lung biopsy was performed under general anesthesia. According to the histopathologic findings of permanent sections, a tissue specimen of diffuse lung disease revealed eosinophil infiltration and the presence of fibroblasts. Immunohistochemical stain showed S-100 protein-positive, as well as cluster of differentiation-68-positive large Langerhans cells. As a result, pulmonary Langerhans cell histiocytosis was diagnosed. The patient had an uncomplicated postoperative course and was discharged from the hospital on postoperative day 5. No recurrence was observed during the 6-month observation period.
authors.affiliation: Department of Surgery, Nihon University School of Medicine, Tokyo, Japan. mura@med.nihon-u.ac.jp
authors.forename: Takashi
authors.initials: T
authors.lastname: Muramatsu
authors.forename: Mie
authors.initials: M
authors.lastname: Shimamura
authors.forename: Motohiko
authors.initials: M
authors.lastname: Furuichi
authors.forename: Tatsuhiko
authors.initials: T
authors.lastname: Nishii
authors.forename: Shinji
authors.initials: S
authors.lastname: Takeshita
authors.forename: Motomi
authors.initials: M
authors.lastname: Shiono
mesh_terms: D000328:Adult; D005260:Female; D006646:Histiocytosis, Langerhans-Cell / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D006801:Humans; D011030:Pneumothorax / Q000209:etiology*; D012008:Recurrence