title: Gold-catalyzed alkylation of silyl enol ethers with ortho-alkynylbenzoic acid esters.
abstract: Unprecedented alkylation of silyl enol ethers has been developed by the use of ortho-alkynylbenzoic acid alkyl esters as alkylating agents in the presence of a gold catalyst. The reaction probably proceeds through the gold-induced in situ construction of leaving groups and subsequent nucleophilic attack on the silyl enol ethers. The generated leaving compound abstracts a proton to regenerate the silyl enol ether structure.
authors.affiliation: Department of Chemistry, Graduate School of Science, Tohoku University, Sendai 980-8578, Japan.
authors.forename: Haruo
authors.initials: H
authors.lastname: Aikawa
authors.forename: Tetsuro
authors.initials: T
authors.lastname: Kaneko
authors.forename: Naoki
authors.initials: N
authors.lastname: Asao
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Yamamoto