title: Comparison of intermittent haemodialysis, prolonged intermittent renal replacement therapy and continuous renal replacement haemofiltration for lithium toxicity: a case report.
abstract: This case report compares three types of renal replacement therapy for acute severe lithium toxicity and is the first to use prolonged intermittent renal replacement therapy (PIRRT). A peak lithium level of 13.2mmol/L was recorded after a 51- year-old man attempted suicide. He was treated with intermittent haemodialysis (IHD), PIRRT and continuous venovenous haemofiltration (CVVH) over 55 hours. Lithium clearance was shown to be comparable between IHD and PIRRT, both of which were superior to CVVH. Expected efficacy of treatment with a single daily session of PIRRT was higher than IHD or CVVH. PIRRT is a useful strategy for dialysis among patients with acute lithium intoxication.
authors.affiliation: Sydney Children's Hospital, Sydney, Australia. andrew.r.bailey@me.com
authors.forename: Andrew R
authors.initials: AR
authors.lastname: Bailey
authors.forename: Vivian J
authors.initials: VJ
authors.lastname: Sathianathan
authors.forename: Angela L
authors.initials: AL
authors.lastname: Chiew
authors.forename: Alastair D
authors.initials: AD
authors.lastname: Paterson
authors.forename: Betty S H
authors.initials: BS
authors.lastname: Chan
authors.forename: Sumesh
authors.initials: S
authors.lastname: Arora
mesh_terms: D058186:Acute Kidney Injury / Q000139:chemically induced / Q000628:therapy*; D005500:Follow-Up Studies; D006440:Hemofiltration / Q000379:methods; D006801:Humans; D016651:Lithium Carbonate / Q000506:poisoning*; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis / Q000379:methods; D017582:Renal Replacement Therapy / Q000379:methods*; D013406:Suicide, Attempted; D013997:Time Factors
chemical_list: D016651:Lithium Carbonate