title: [A case of IgG4-related sclerosing disorders involving the mesentery and the pancreas].
abstract: A 78-year-old man presented with upper abdominal pain. He underwent an abdominal computed tomography scan which revealed irregularly shaped mass lesions in the mesentery and in the pancreatic head and body. The mass lesions were suspected to be pancreatic cancer with peritoneal dissemination and a surgical biopsy was performed. Histologic studies revealed lymphoplasmacytic sclerosing pancreatitis with significant infiltration of IgG4-positive plasma cells. His serum IgG4 level was 223 mg/dl. Findings from histologic and serum studies were compatible with IgG4-related sclerosing disorders. The mass lesions responded to steroid therapy and disappeared. The difficulty in making a definitive diagnosis is discussed.
authors.affiliation: Department of Gastroenterology, Tobato Kyoritsu Hospital, and Department of Medicine, Kurume University School of Medicine.
authors.forename: Ryosuke
authors.initials: R
authors.lastname: Sakemi
authors.forename: Suketo
authors.initials: S
authors.lastname: So
authors.forename: Yosuke
authors.initials: Y
authors.lastname: Morimitsu
authors.forename: Daiji
authors.initials: D
authors.lastname: Uchiyama
authors.forename: Seiya
authors.initials: S
authors.lastname: Kakiuchi
authors.forename: Yuji
authors.initials: Y
authors.lastname: Ishihara
authors.forename: Yu
authors.initials: Y
authors.lastname: Matsushima
authors.forename: Yasuhiko
authors.initials: Y
authors.lastname: Kubo
authors.forename: Satoru
authors.initials: S
authors.lastname: Matsugaki
authors.forename: Tetsujiro
authors.initials: T
authors.lastname: Ono
authors.forename: Junko
authors.initials: J
authors.lastname: Takane
authors.forename: Ei
authors.initials: E
authors.lastname: Sasaki
authors.forename: Miyuki
authors.initials: M
authors.lastname: Sakemi
authors.forename: Masayuki
authors.initials: M
authors.lastname: Shimokobe
authors.forename: Michio
authors.initials: M
authors.lastname: Sata
mesh_terms: D000368:Aged; D001327:Autoimmune Diseases / Q000473:pathology; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis*; D008297:Male; D008643:Mesentery / Q000473:pathology*; D010182:Pancreatic Diseases / Q000473:pathology*; D010195:Pancreatitis / Q000473:pathology; D012598:Sclerosis / Q000473:pathology*
chemical_list: D007074:Immunoglobulin G