title: β-Cyclodextrin conjugated magnetic nanoparticles for diazepam removal from blood.
abstract: β-CD conjugated magnetic nanoparticles that serve as a hemoadsorbent for diazepam removal are fabricated. The diazepam is arrested by the conjugated β-CD and then the adsorbed diazepam is efficiently removed by an external magnetic field. These particles have potential applications in hemoperfusion or separation of other toxins and drugs.
authors.affiliation: Key Laboratory of Biorheological Science and Technology, Ministry of Education, College of Bioengineering, Chongqing University, Chongqing, PR China. Kaiyong_cai@cqu.edu.cn
authors.forename: Kaiyong
authors.initials: K
authors.lastname: Cai
authors.forename: Jinghua
authors.initials: J
authors.lastname: Li
authors.forename: Zhong
authors.initials: Z
authors.lastname: Luo
authors.forename: Yan
authors.initials: Y
authors.lastname: Hu
authors.forename: Yanhua
authors.initials: Y
authors.lastname: Hou
authors.forename: Xingwei
authors.initials: X
authors.lastname: Ding
mesh_terms: D000327:Adsorption; D014151:Anti-Anxiety Agents / Q000097:blood / Q000302:isolation & purification*; D003975:Diazepam / Q000097:blood / Q000302:isolation & purification*; D006801:Humans; D008280:Magnetics / Q000379:methods*; D053758:Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D047392:beta-Cyclodextrins / Q000737:chemistry*
chemical_list: D014151:Anti-Anxiety Agents; D047392:beta-Cyclodextrins; C031215:betadex; D003975:Diazepam