title: Microbial production of diols as platform chemicals: recent progresses.
abstract: Diols are chemicals with two hydroxyl groups which have a wide range of appealing applications as chemicals and fuels. In particular, four diol compounds, namely 1,3-propanediol (1,3-PDO), 1,2-propanediol (1,2-PDO), 2,3-butanediol (2,3-BDO) and 1,4-butanediol (1,4-BDO) can be biotechnologically produced by direct microbial bioconversion of renewable materials. These diols are considered as platform green chemicals. We review and discuss here the recent development in the microbial production of these diols, especially regarding the engineering of production strains and optimization of the fermentation processes.
authors.affiliation: Institute of Bioprocess and Biosystems Engineering, Hamburg University of Technology, Denickestr. 15, D-21071 Hamburg, Germany. AZE@tuhh.de
authors.forename: An-Ping
authors.initials: AP
authors.lastname: Zeng
authors.forename: Wael
authors.initials: W
authors.lastname: Sabra
mesh_terms: D002072:Butylene Glycols / Q000737:chemistry / Q000378:metabolism*; D005285:Fermentation; D007218:Industrial Microbiology / Q000639:trends*; D011409:Propylene Glycols / Q000737:chemistry / Q000378:metabolism*
chemical_list: D002072:Butylene Glycols; D011409:Propylene Glycols; C041787:1,3-propanediol; C039681:1,4-butanediol