title: Transcriptional regulation of ompF2, an ompF paralogue, in Yersinia pestis.
abstract: A regulatory circuit composed of three porins (OmpF, OmpC, and OmpX) and two transcriptional regulators (OmpR and CRP) has previously been characterized in Yersinia pestis . In this follow-up study, OmpF2, an OmpF paralogue, was integrated into this regulatory circuit. Only basal expression was detected for ompF2 in the wild-type strain under different osmotic conditions. The ompF2 transcription was dramatically enhanced with increasing medium osmolarity in the ompR null mutant background. The CRP regulator had no regulatory effect on ompF2 under the growth conditions tested.
authors.affiliation: State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, People's Republic of China.
authors.forename: He
authors.initials: H
authors.lastname: Gao
authors.forename: Yiquan
authors.initials: Y
authors.lastname: Zhang
authors.forename: Yafang
authors.initials: Y
authors.lastname: Tan
authors.forename: Li
authors.initials: L
authors.lastname: Wang
authors.forename: Xiao
authors.initials: X
authors.lastname: Xiao
authors.forename: Zhaobiao
authors.initials: Z
authors.lastname: Guo
authors.forename: Dongsheng
authors.initials: D
authors.lastname: Zhou
authors.forename: Ruifu
authors.initials: R
authors.lastname: Yang
mesh_terms: D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism*; D002373:Cyclic AMP Receptor Protein / Q000378:metabolism; D015964:Gene Expression Regulation, Bacterial; D053263:Gene Regulatory Networks; D009154:Mutation; D018272:Porins / Q000235:genetics / Q000378:metabolism*; D011401:Promoter Regions, Genetic; D012329:RNA, Bacterial / Q000235:genetics; D014158:Transcription, Genetic; D015010:Yersinia pestis / Q000235:genetics* / Q000378:metabolism
chemical_list: D001426:Bacterial Proteins; D002373:Cyclic AMP Receptor Protein; C109237:OmpF protein; D018272:Porins; D012329:RNA, Bacterial