title: Aptamer-based highly sensitive electrochemiluminescent detection of thrombin via nanoparticle layer-by-layer assembled amplification labels.
abstract: The preparation and use of a new class of signal amplification label, the CdTe quantum dot layer-by-layer assembled polystyrene microbead composite, for amplified ultrasensitive electrochemiluminescent detection of thrombin is described.
authors.affiliation: Key Laboratory on Luminescence and Real-Time Analysis, Ministry of Education, School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, PR China.
authors.forename: Ying
authors.initials: Y
authors.lastname: Chen
authors.forename: Bingying
authors.initials: B
authors.lastname: Jiang
authors.forename: Yun
authors.initials: Y
authors.lastname: Xiang
authors.forename: Yaqin
authors.initials: Y
authors.lastname: Chai
authors.forename: Ruo
authors.initials: R
authors.lastname: Yuan
mesh_terms: D000818:Animals; D052157:Aptamers, Nucleotide / Q000737:chemistry*; D019187:Cadmium Compounds / Q000737:chemistry*; D055664:Electrochemical Techniques / Q000379:methods*; D057230:Limit of Detection; D008163:Luminescent Measurements / Q000379:methods*; D008863:Microspheres; D045663:Quantum Dots; D013691:Tellurium / Q000737:chemistry*; D013917:Thrombin / Q000032:analysis*
chemical_list: D052157:Aptamers, Nucleotide; D019187:Cadmium Compounds; C081676:thrombin aptamer; D013917:Thrombin; D013691:Tellurium; C028337:cadmium telluride