title: Extensively drug-resistant tuberculosis: New Zealand's first case and the challenges of management in a low-prevalence country.
abstract: In 2010, an immigrant from Burma was the first person to be diagnosed in New Zealand with extensively drug-resistant tuberculosis (XDR-TB). The strain of Mycobacterium tuberculosis is the most resistant reported to date in Australasia. Key difficulties of managing this disease in a low-prevalence country were delays from drug-susceptibility testing and in acquiring appropriate medicines, and a lack of evidence-based guidelines. Solutions are needed for New Zealand and the wider region as more cases of XDR-TB are likely to be encountered in the future.
authors.affiliation: Dunedin Hospital, Dunedin, New Zealand. tzeliang.gohATsoutherndhb.govt.nz
authors.forename: Tze Liang
authors.initials: TL
authors.lastname: Goh
authors.forename: Cindy R
authors.initials: CR
authors.lastname: Towns
authors.forename: Katharine L
authors.initials: KL
authors.lastname: Jones
authors.forename: Joshua T
authors.initials: JT
authors.lastname: Freeman
authors.forename: Colin S
authors.initials: CS
authors.lastname: Wong
mesh_terms: D000081:Acetamides / Q000627:therapeutic use; D000328:Adult; D010131:Aminosalicylic Acid / Q000627:therapeutic use; D000995:Antitubercular Agents / Q000627:therapeutic use*; D001372:Aza Compounds / Q000627:therapeutic use; D003523:Cycloserine / Q000627:therapeutic use; D054242:Emigrants and Immigrants; D054908:Extensively Drug-Resistant Tuberculosis / Q000175:diagnosis* / Q000188:drug therapy*; D024841:Fluoroquinolones; D006801:Humans; D015378:Imipenem / Q000627:therapeutic use; D000069349:Linezolid; D008198:Lymph Nodes / Q000000981:diagnostic imaging; D008297:Male; D000077266:Moxifloxacin; D002052:Myanmar / Q000208:ethnology; D009520:New Zealand; D023303:Oxazolidinones / Q000627:therapeutic use; D011804:Quinolines / Q000627:therapeutic use; D011859:Radiography
chemical_list: D000081:Acetamides; D000995:Antitubercular Agents; D001372:Aza Compounds; D024841:Fluoroquinolones; D023303:Oxazolidinones; D011804:Quinolines; D010131:Aminosalicylic Acid; D015378:Imipenem; D003523:Cycloserine; D000069349:Linezolid; D000077266:Moxifloxacin