title: Facile functionalization of polypeptides by thiol-yne photochemistry for biomimetic materials synthesis.
abstract: Rapid and highly efficient side-chain functionalization of polypeptides was achieved via combination of ring-opening polymerization of a new clickable monomer of γ-propargyl-L-glutamate N-carboxyanhydride (PLG-NCA) and thiol-yne photochemistry, which provides a convenient and universal route to prepare diverse polypeptide-based biomimetic hybrid materials.
authors.affiliation: Institute of Polymer Science, DSAPM Lab, School of Chemistry and Chemical Engineering, Sun Yat-Sen University, GuangZhou, China.
authors.forename: Yugang
authors.initials: Y
authors.lastname: Huang
authors.forename: Yonghong
authors.initials: Y
authors.lastname: Zeng
authors.forename: Jianwen
authors.initials: J
authors.lastname: Yang
authors.forename: Zhaohua
authors.initials: Z
authors.lastname: Zeng
authors.forename: Fangming
authors.initials: F
authors.lastname: Zhu
authors.forename: Xudong
authors.initials: X
authors.lastname: Chen
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D040761:Biomimetic Materials / Q000138:chemical synthesis* / Q000737:chemistry*; D018698:Glutamic Acid / Q000737:chemistry; D057927:Hydrophobic and Hydrophilic Interactions; D007700:Kinetics; D010455:Peptides / Q000737:chemistry*; D055668:Photochemical Processes; D058105:Polymerization; D013438:Sulfhydryl Compounds / Q000737:chemistry*
chemical_list: D000480:Alkynes; D010455:Peptides; D013438:Sulfhydryl Compounds; D018698:Glutamic Acid