title: [Significance of radiosurgery in the treatment of brain metastases].
abstract: Brain metastases are diagnosed in about 30% adult patients with generalized carcinomas, their accompanying severe neurological symptoms cause worsening quality of patient's life. The development of magnetic resonance imaging and stereotactically guided radiosurgery and radiotherapy enable to apply relatively high doses to well defined intracranial target volumes. Progression free survival after irradiation of brain lesions depends on several prognostic factors. Radiosurgery using gamma knife is an effective treatment with low rate of postradiation complications.
authors.affiliation: Oddeleni stereotaktické a radiarní neurochirurgie Nemocnice Na Homolce, Praha. gabriela.simonova@homolka.cz
authors.forename: Gabriela
authors.initials: G
authors.lastname: Simonová
authors.forename: Roman
authors.initials: R
authors.lastname: Liscák
mesh_terms: D001932:Brain Neoplasms / Q000556:secondary* / Q000601:surgery*; D018572:Disease-Free Survival; D006801:Humans; D053208:Kaplan-Meier Estimate; D011379:Prognosis; D016634:Radiosurgery