title: Metabolic Profile of Offspring from Diabetic Wistar Rats Treated with Mentha piperita (Peppermint).
abstract: This study aimed at evaluating glycemia and lipid profile of offspring from diabetic Wistar rats treated with Mentha piperita (peppermint) juice. Male offspring from nondiabetic dams (control group: 10 animals treated with water and 10 treated with peppermint juice) and from dams with streptozotocin-induced severe diabetes (diabetic group: 10 animals treated with water and 10 treated with peppermint juice) were used. They were treated during 30 days, and, after the treatment period, levels of glycemia, triglycerides, total cholesterol, and fractions were analyzed in the adult phase. The offspring from diabetic dams treated with peppermint showed significantly reduced levels of glucose, cholesterol, LDL-c, and triglycerides and significant increase in HDL-c levels. The use of the M. piperita juice has potential as culturally appropriate strategy to aid in the prevention of DM, dyslipidemia, and its complications.
authors.affiliation: Department of Biochemistry, Faculty of Medicine, UNIMAR, 17500-021 Marília, SP, Brazil.
authors.forename: Sandra M
authors.initials: SM
authors.lastname: Barbalho
authors.forename: Débora C
authors.initials: DC
authors.lastname: Damasceno
authors.forename: Ana Paula Machado
authors.initials: AP
authors.lastname: Spada
authors.forename: Vanessa Sellis
authors.initials: VS
authors.lastname: da Silva
authors.forename: Karla Aparecida
authors.initials: KA
authors.lastname: Martuchi
authors.forename: Marie
authors.initials: M
authors.lastname: Oshiiwa
authors.forename: Flávia M V Farinazzi
authors.initials: FM
authors.lastname: Machado
authors.forename: Claudemir Gregório
authors.initials: CG
authors.lastname: Mendes