title: Stereoselective aza-Darzens reactions of tert-butanesulfinimines: convenient access to chiral aziridines.
abstract: Stereoselective synthesis of 2,3-di- and 2,2',3-tri-substituted aziridines in good yields and excellent diastereoselectivities are achieved through aza-Darzens reactions of a range of tert-butanesulfinyl aldimines and ketimines with ethyl bromoacetate.
authors.affiliation: School of Chemistry, University of Nottingham, Nottingham, UK NG7 2RD.
authors.forename: Toni Moragas
authors.initials: TM
authors.lastname: Solá
authors.forename: Ian
authors.initials: I
authors.lastname: Churcher
authors.forename: William
authors.initials: W
authors.lastname: Lewis
authors.forename: Robert A
authors.initials: RA
authors.lastname: Stockman
mesh_terms: D001388:Aziridines / Q000138:chemical synthesis* / Q000737:chemistry; D018360:Crystallography, X-Ray; D007097:Imines / Q000737:chemistry*; D008958:Models, Molecular; D015394:Molecular Structure; D013237:Stereoisomerism; D013452:Sulfonium Compounds / Q000737:chemistry*
chemical_list: D001388:Aziridines; D007097:Imines; D013452:Sulfonium Compounds; C522016:sulfinimine