title: Delivery devices for the administration of paediatric formulations: overview of current practice, challenges and recent developments.
abstract: The European Paediatric Formulation Initiative (EuPFI), a group consisting of paediatric formulation experts from industry, academia and clinical pharmacy was founded with the aim of raising awareness of paediatric formulation issues. It is imperative that paediatric medicines can be administered accurately to ensure the correct dose is provided and that the administration device is easy to use and acceptable from the patient's and carer's perspectives. This reflection paper provides an overview of currently available paediatric administration devices and highlights some of the challenges associated with, recommendations and recent developments in delivery devices for the oral, inhaled, parenteral, nasal and ocular administration of paediatric formulations, on behalf of the EuPFI.
authors.affiliation: Pharmaceutical Development, AstraZeneca, Bakewell Road, Loughborough, Leicestershire, LE11 5RH, United Kingdom. jenny.walsh@astrazeneca.com
authors.forename: Jennifer
authors.initials: J
authors.lastname: Walsh
authors.forename: Deborah
authors.initials: D
authors.lastname: Bickmann
authors.forename: Joerg
authors.initials: J
authors.lastname: Breitkreutz
authors.forename: Maryvonne
authors.initials: M
authors.lastname: Chariot-Goulet
mesh_terms: D000280:Administration, Inhalation; D000284:Administration, Oral; D002648:Child; D016503:Drug Delivery Systems / Q000295:instrumentation* / Q000379:methods / Q000639:trends; D004867:Equipment Design; D006801:Humans; D007260:Infusion Pumps; D009330:Nebulizers and Vaporizers; D010372:Pediatrics