title: Design of chiral sulfoxide-olefins as a new class of sulfur-based olefin ligands for asymmetric catalysis.
abstract: The design and development of a novel class of chiral sulfur-olefin hybrid ligands with high synthetic feasibility are described. These new sulfoxide-olefin ligands showed excellent catalytic activities and enantioselectivities (up to 98% ee) in rhodium-catalyzed asymmetric 1,4-addition reactions of aryl boronic acids to α,β-unsaturated carbonyl compounds.
authors.affiliation: Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China.
authors.forename: Wei-Yi
authors.initials: WY
authors.lastname: Qi
authors.forename: Ting-Shun
authors.initials: TS
authors.lastname: Zhu
authors.forename: Ming-Hua
authors.initials: MH
authors.lastname: Xu
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D002384:Catalysis; D008024:Ligands; D015394:Molecular Structure; D013237:Stereoisomerism; D013454:Sulfoxides / Q000737:chemistry*; D013455:Sulfur / Q000737:chemistry*
chemical_list: D000475:Alkenes; D008024:Ligands; D013454:Sulfoxides; D013455:Sulfur