title: An outbreak of Fusarium solani endophthalmitis after cataract surgery in an eye training and research hospital in Istanbul.
abstract: To report an outbreak of Fusarium solani endophthalmitis after uneventful cataract surgeries performed on the same day in the same operating room. Nine patients underwent phacoemulsification at 4th Clinic of Beyoglu Eye Training and Research Hospital in Istanbul. Cefuroxime axetyl was injected intracamerally from the same vial to all patients at the end of surgery. All patients developed acute postoperative endophthalmitis. Presentation, cultural studies, treatment, clinical responses and risk factors were evaluated. Cultural and DNA sequence findings revealed F. solani. Antifungal therapy was begun and pars plana vitrectomy, intraocular lens and capsule extraction were performed. Corneal involvement was correlated with old age and systemic disease. Fusarium solani should be considered in acute postoperative endophthalmitis. This infection can be controlled with early and aggressive combined antifungal and surgical treatment. The patients with corneal involvement had poor prognosis. It is important to use solutions prepared separately for each patient.
authors.affiliation: Beyoglu Eye Training and Research Hospital, Istanbul, Turkey. hulyagungel@msn.com
authors.forename: Hülya
authors.initials: H
authors.lastname: Güngel
authors.forename: Mümin Hakan
authors.initials: MH
authors.lastname: Eren
authors.forename: Eylem Yaman
authors.initials: EY
authors.lastname: Pınarcı
authors.forename: Ciğdem
authors.initials: C
authors.lastname: Altan
authors.forename: Deniz Oygar
authors.initials: DO
authors.lastname: Baylançiçek
authors.forename: Necip
authors.initials: N
authors.lastname: Kara
authors.forename: Tanıl
authors.initials: T
authors.lastname: Gürsel
authors.forename: Yildiz
authors.initials: Y
authors.lastname: Yegenoğlu
authors.forename: Serdar
authors.initials: S
authors.lastname: Susever
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000935:Antifungal Agents / Q000008:administration & dosage; D002387:Cataract Extraction / Q000009:adverse effects*; D003428:Cross Infection / Q000453:epidemiology* / Q000382:microbiology / Q000473:pathology / Q000628:therapy; D004196:Disease Outbreaks; D009877:Endophthalmitis / Q000453:epidemiology* / Q000382:microbiology / Q000473:pathology / Q000628:therapy; D015821:Eye Infections, Fungal / Q000453:epidemiology* / Q000382:microbiology / Q000473:pathology / Q000628:therapy; D005260:Female; D060585:Fusariosis / Q000453:epidemiology* / Q000382:microbiology / Q000473:pathology / Q000628:therapy; D005670:Fusarium / Q000235:genetics / Q000254:growth & development / Q000302:isolation & purification*; D006761:Hospitals; D006801:Humans; D008297:Male; D008875:Middle Aged; D013530:Surgical Wound Infection / Q000453:epidemiology / Q000382:microbiology / Q000473:pathology / Q000628:therapy; D014821:Vitrectomy
chemical_list: D000935:Antifungal Agents