title: Anaphylactic reaction induced by a polysulfone/polyvinylpyrrolidone membrane in the 10th session of hemodialysis with the same dialyzer.
abstract: The majority of severe hypersensitivity reactions in hemodialysis patients have occurred due to sensitization to ethylene oxide or to nonbiocompatible membrane dialyzers. The use of polysulfone dialyzers rarely causes hypersensitivity reactions. In the present study, we describe a case of severe life-threatening reactions induced by polysulfone dialyzers (from different manufacturers subjected to a variety of sterilization methods), which occurred after 9 sessions of hemodialysis with the same prescription, exemplifying the complexity of such reactions.
authors.affiliation: Department of Internal Medicine, Nephrology Division, University of Sao Paulo School of Medicine, Sao Paulo, Brazil. igordenizarde@yahoo.com.br
authors.forename: Igor Denizarde
authors.initials: ID
authors.lastname: Bacelar Marques
authors.forename: Karina França
authors.initials: KF
authors.lastname: Pinheiro
authors.forename: Lílian Pires
authors.initials: LP
authors.lastname: de Freitas do Carmo
authors.forename: Maristela Carvalho
authors.initials: MC
authors.lastname: Costa
authors.forename: Hugo
authors.initials: H
authors.lastname: Abensur
mesh_terms: D000368:Aged; D000707:Anaphylaxis / Q000139:chemically induced*; D002908:Chronic Disease; D015312:Hemodialysis Solutions; D006801:Humans; D007674:Kidney Diseases / Q000628:therapy; D008297:Male; D008567:Membranes, Artificial; D011108:Polymers / Q000009:adverse effects*; D011205:Povidone / Q000009:adverse effects*; D013450:Sulfones / Q000009:adverse effects*
chemical_list: D015312:Hemodialysis Solutions; D008567:Membranes, Artificial; D011108:Polymers; D013450:Sulfones; C017662:polysulfone P 1700; D011205:Povidone