title: Tuberculosis-associated chronic kidney disease.
abstract: Extrapulmonary tuberculosis (TB) account for approximately 15-20% of TB cases in immunocompetent patients. The genitourinary system is the third most commonly affected site. We report the case of a 20-year-old man admitted with fever, chills, dry cough, right flank pain, and oliguria who developed renal function loss. The pyelogram evidenced silence of the right kidney, and the abdominal and pelvic magnetic resonance showed significant dilation of the right pyelocaliceal system and proximal ureter. Biopsies of renal cortex and retroperitoneal lymph nodes showed caseous granuloma consistent with TB. Treatment was started with rifampicin, isoniazid, pyrazinamide, and ethambutol, and the patient presented a favorable outcome but with non-dialytic chronic kidney disease. This case illustrates a case of chronic kidney disease secondary to TB in a young, otherwise healthy man.
authors.affiliation: Division of Nephrology, Department of Internal Medicine, Federal University of Ceará, Fortaleza, Ceará, Brazil. jobson.lopes@hotmail.com
authors.forename: Jobson Lopes
authors.initials: JL
authors.lastname: de Oliveira
authors.forename: Geraldo Bezerra
authors.initials: GB
authors.lastname: da Silva Junior
authors.forename: Elizabeth De Francesco
authors.initials: Ede F
authors.lastname: Daher
mesh_terms: D000995:Antitubercular Agents / Q000627:therapeutic use; D004977:Ethambutol / Q000627:therapeutic use; D005334:Fever; D006801:Humans; D007538:Isoniazid / Q000627:therapeutic use; D007676:Kidney Failure, Chronic / Q000188:drug therapy / Q000209:etiology*; D008297:Male; D011718:Pyrazinamide / Q000627:therapeutic use; D006435:Renal Dialysis; D012293:Rifampin / Q000627:therapeutic use; D014376:Tuberculosis / Q000150:complications* / Q000188:drug therapy; D055815:Young Adult
chemical_list: D000995:Antitubercular Agents; D011718:Pyrazinamide; D004977:Ethambutol; D007538:Isoniazid; D012293:Rifampin