title: [Significant regression of a cavernous hepatic hemangioma to a sclerosed hemangioma over 12 years: a case study].
abstract: A sixties woman was found to have diagnosed by abdominal ultrasonography with a tumor in the left lobe of the liver and was referred to our institution in 1998. Abdominal magnetic resonance imaging (MRI) showed a typical, 70×45 mm cavernous hemangioma, which was followed up by annual MRI. In 2006, 8 years after the initial diagnosis, the MRI showed that the tumor had reduced to 30×15 mm. Although atypical of hemangioma, review of the annual observations indicated a diagnosis of regressive hemangioma, which also accorded with clinical observations. In 2009, a liver biopsy was performed by laparotomy during gastrectomy for gastric cancer. Pathological examination of the biopsy revealed sclerosed hemangioma tissue, confirming the diagnosis of regression of a cavernous hemangioma to a sclerosed hemangioma over 12 years.
authors.affiliation: Department of Medicine and Molecular Science, Division of Frontier Medical Science, Programs for Biomedical Research, Graduate School of Biomedical Science, Hiroshima University, and Department of Anatomical Pathology, Hiroshima University Hospital. dmiyaki@hiroshima-u.ac.jp
authors.forename: Daisuke
authors.initials: D
authors.lastname: Miyaki
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Aikata
authors.forename: Koji
authors.initials: K
authors.lastname: Waki
authors.forename: Eisuke
authors.initials: E
authors.lastname: Murakami
authors.forename: Yoshimasa
authors.initials: Y
authors.lastname: Hashimoto
authors.forename: Yuko
authors.initials: Y
authors.lastname: Nagaoki
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Katamura
authors.forename: Tomokazu
authors.initials: T
authors.lastname: Kawaoka
authors.forename: Shintaro
authors.initials: S
authors.lastname: Takaki
authors.forename: Akira
authors.initials: A
authors.lastname: Hiramatsu
authors.forename: Michio
authors.initials: M
authors.lastname: Imamura
authors.forename: Shoichi
authors.initials: S
authors.lastname: Takahashi
authors.forename: Toshihide
authors.initials: T
authors.lastname: Ohya
authors.forename: Hideto
authors.initials: H
authors.lastname: Sakimoto
authors.forename: Koji
authors.initials: K
authors.lastname: Arihiro
authors.forename: Kazuaki
authors.initials: K
authors.lastname: Chayama
mesh_terms: D005260:Female; D006392:Hemangioma, Cavernous / Q000473:pathology*; D018219:Histiocytoma, Benign Fibrous / Q000473:pathology*; D006801:Humans; D008113:Liver Neoplasms / Q000473:pathology*; D008875:Middle Aged; D009365:Neoplasm Regression, Spontaneous; D013997:Time Factors