title: The results of transcatheter closure of VSD using Amplatzer® device and Nit Occlud® Lê coil.
abstract: OBJECTIVE
  We retrospectively reviewed the result of patients who underwent transcatheter closure of ventricular septal defect (VSD) using Amplatzer® Perimembranous or Amplatzer® muscular VSD device (the Amplatzer® group) and Nit Occlud® Lê VSD Coil (the Pfm group).
  
  
  BACKGROUND
  Perimembranous type (PmVSD) and doubly committed subarterial (DCSA) VSD were the major isolated congenital heart defects in Thai children. Transcatheter device closure technique for both types of VSD has emerged as an alternative treatment to surgery.
  
  
  METHODS
  Retrospectively, data was reviewed between 2003 and 2009.
  
  
  RESULTS
  116 patients were enrolled. Device or coil was successfully implanted in 94%. Complete closure at 24 hr is slightly higher in the Amplatzer® group. The average size of VSD in the Amplatzer® group was larger than the Pfm group (P = 0.001). The Pfm coil was primarily deployed in DCSA VSD when compared with the Amplatzer® group (P < 0.01). At 6 months follow-up the residual shunt was comparable (P = 0.054). There was only one transient AV block (AVB) in the Pfm group and 5 AVB in the Amplatzer® group. Four pacemakers were placed in the Amplatzer® group.
  
  
  CONCLUSIONS
  Transcatheter closure of VSD in both Pm VSD and DCSA can be achieved by using either of the device. The Amplatzer® VSD device had the advantage of closure of larger defects with immediate less residual shunt but appeared to have a significant number of 3° AVB, which required pacemaker implantation. The Nit Occlud® Lê VSD Coil had the advantage of closure of both types of defects, in particular DCSA VSD with only small residual shunt.
authors.affiliation: Division of Cardiology, Department of Pediatric, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand. pikky85@hotmail.com
authors.forename: Paweena
authors.initials: P
authors.lastname: Chungsomprasong
authors.forename: Kritvikrom
authors.initials: K
authors.lastname: Durongpisitkul
authors.forename: Chodchanok
authors.initials: C
authors.lastname: Vijarnsorn
authors.forename: Jarupim
authors.initials: J
authors.lastname: Soongswang
authors.forename: Trong Phi
authors.initials: TP
authors.lastname: Lê
mesh_terms: D000293:Adolescent; D000328:Adult; D006328:Cardiac Catheterization / Q000009:adverse effects / Q000295:instrumentation*; D016009:Chi-Square Distribution; D002648:Child; D002675:Child, Preschool; D017548:Echocardiography, Transesophageal; D005260:Female; D006345:Heart Septal Defects, Ventricular / Q000175:diagnosis / Q000628:therapy*; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D011474:Prosthesis Design; D015641:Radiography, Interventional; D012189:Retrospective Studies; D018570:Risk Assessment; D012307:Risk Factors; D055989:Septal Occluder Device; D013785:Thailand; D013997:Time Factors; D016896:Treatment Outcome; D055815:Young Adult