title: Evolution. In evolution, the sum is less than its parts.
authors.affiliation: Department of Biology, University of Pennsylvania, Philadelphia, PA 19103, USA.
authors.forename: Sergey
authors.initials: S
authors.lastname: Kryazhimskiy
authors.forename: Jeremy A
authors.initials: JA
authors.lastname: Draghi
authors.forename: Joshua B
authors.initials: JB
authors.lastname: Plotkin
mesh_terms: D000222:Adaptation, Physiological; D005075:Biological Evolution; D004843:Epistasis, Genetic; D004926:Escherichia coli / Q000235:genetics* / Q000502:physiology; D019143:Evolution, Molecular; D056084:Genetic Fitness; D016680:Genome, Bacterial; D020601:Methylobacterium extorquens / Q000235:genetics* / Q000502:physiology; D009154:Mutation