title: [An analysis of intervention outcome in non-ST segment elevation acute coronary syndrome in elderly patients].
abstract: OBJECTIVE
  To investigate the effect and safety of early intervention and delayed intervention therapy on elderly patients and younger patients with non-ST segment elevation acute coronary syndrome.
  
  
  METHODS
  The patients with non-ST segment elevation acute coronary syndrome were randomly divided into early intervention group (coronary angiography taken within 24 hours after grouping) and delayed intervention group (coronary angiography taken after 36 hours after grouping). The primary endpoint was a composite endpoint of death, myocardial infarction and stroke during 180 days follow-up.
  
  
  RESULTS
  A total of 815 patients were enrolled, including 198 elderly patients aged 75 years and above, and 617 younger patients aged below 75 years. The elderly patients had a greater incidence of the primary endpoint than that of younger patients (P = 0.00). The primary endpoint of early intervention group were obviously lower than that of delayed intervention group of younger patients (P = 0.01). There was no significant difference in primary endpoint incidence of early intervention group and delayed intervention group of the elderly patients (P = 0.39).
  
  
  CONCLUSIONS
  The elderly patients with non-ST segment elevation acute coronary syndrome who underwent intervention had greater incidence of death and myocardial infarction. Early intervention reduced the rate of myocardial infarction for the younger patients. There was no significant difference in primary endpoint incidence between early intervention and delayed intervention among elderly patients.
authors.affiliation: Chinese Academy of Medical, Beijing 100037, China. zhangjun-cv@263.net
authors.forename: Jun
authors.initials: J
authors.lastname: Zhang
authors.forename: Jun
authors.initials: J
authors.lastname: Zhu
authors.forename: Jue
authors.initials: J
authors.lastname: Chen
authors.forename: Wei-xian
authors.initials: WX
authors.lastname: Yang
authors.forename: Yan
authors.initials: Y
authors.lastname: Liang
authors.forename: Chun-li
authors.initials: CL
authors.lastname: Shao
mesh_terms: D054058:Acute Coronary Syndrome / Q000503:physiopathology* / Q000628:therapy*; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D015906:Angioplasty, Balloon, Coronary; D061345:Early Medical Intervention; D004562:Electrocardiography; D023381:Endpoint Determination; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome