title: Multicolor saccharide-sensing chips based on boronic acid-containing thin films showing stepwise release and binding of dyes.
abstract: A novel saccharide sensor that shows a distinct color change resembling a "traffic signal" was developed. By copolymerizing a boronic acid monomer and an amine monomer on a glass plate, a boronic acid-containing thin film was obtained. After adsorbing anionic blue and yellow dyes, the thin film was immersed in aqueous saccharide solutions containing a cationic red dye. As saccharide concentration increased, the thin film changed its color from green to red via yellow. Origin of the distinct color change was attributed to a stepwise release and binding of dyes.
authors.affiliation: Department of Biotechnology and Environmental Chemistry, Kitami Institute of Technology, 165 Koen-cho, Kitami, Hokkaido 090-8507, Japan.
authors.forename: Yuto
authors.initials: Y
authors.lastname: Iwami
authors.forename: Takenori
authors.initials: T
authors.lastname: Yokozawa
authors.forename: Wakana
authors.initials: W
authors.lastname: Takayoshi
authors.forename: Yasumasa
authors.initials: Y
authors.lastname: Kanekiyo
mesh_terms: D001897:Boronic Acids / Q000737:chemistry*; D002241:Carbohydrates / Q000032:analysis*; D003116:Color; D004396:Coloring Agents / Q000737:chemistry*; D058105:Polymerization; D012996:Solutions
chemical_list: D001897:Boronic Acids; D002241:Carbohydrates; D004396:Coloring Agents; D012996:Solutions