title: Value of β2-microglobulin in the serum of healthy subjects older than 40 years.
abstract: The aim of this research was to determine if the age of healthy subjects older than 40 years of age has an influence on the concentration of β(2) -microglobulin in the serum of subjects of different populations. We examined the values of β(2) -microglobulin in the serum of 51 healthy subjects aged 40-86 years using the microparticle enzyme immunoassay AxSYM β(2) -microglobulin test. The reference values of β(2) -microglobulin according to the nonparametric statistical method is 0.95-2.73 mg/L. A correlation was found between β(2) -microglobulin and age: 40-50 years (0.94-1.54 mg/L), 51-65 years (0.96-2.62 mg/L), and >65 years (1.13-2.84 mg/L). There was no significant statistical difference of β(2) -microglobulin between genders (P > 0.05); however, there was a statistically significant difference between the concentration of β(2) -microglobulin and the subjects' age. (Spearman's rank correlation coefficient ρ = 0.66; P < 0.01). A direct correlation between age and the concentration of β(2) -microglobulin was observed. This research is a contribution to determining reference values of β(2) -microglobulin in subjects of different populations.
authors.affiliation: Departments of Orthopaedics, General County Hospital Požega, Požega, Croatia. damirmatokovic@gmail.com
authors.forename: Damir
authors.initials: D
authors.lastname: Matoković
authors.forename: Miroslav
authors.initials: M
authors.lastname: Hašpl
authors.forename: Petar
authors.initials: P
authors.lastname: Petrić
authors.forename: Sanja
authors.initials: S
authors.lastname: Skorvaga
authors.forename: Marijana Tomić
authors.initials: MT
authors.lastname: Rajić
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques / Q000379:methods*; D008297:Male; D008875:Middle Aged; D018709:Statistics, Nonparametric; D001613:beta 2-Microglobulin / Q000097:blood*
chemical_list: D001613:beta 2-Microglobulin