title: Suture granuloma showing false-positive finding on PET/CT after head and neck cancer surgery.
abstract: We report herein two cases of suture granuloma showing focal intense 2-deoxy-2-[(18)F]fluoro-d-glucose (FDG)-uptake in positron emission tomography (PET). Follow-up FDG-PET after surgical intervention for head and neck cancer revealed lesions with high FDG-uptake, which were highly suspected of being a recurrent tumor. The lesions were subjected to excisional biopsy for definitive diagnosis. Histopathological examination proved them to be suture granulomas caused by non-absorbable silk sutures. It should be emphasized that suture granulomas can show false-positive findings on FDG-PET, thus requiring differential diagnosis from recurrent tumors.
authors.affiliation: Department of Otolaryngology, Kobe City Medical Center General Hospital, 4-6 Minatojima-Nakamachi, Chuo-ku, Kobe 650-0046, Japan.
authors.forename: Masahiro
authors.initials: M
authors.lastname: Kikuchi
authors.forename: Yuji
authors.initials: Y
authors.lastname: Nakamoto
authors.forename: Shogo
authors.initials: S
authors.lastname: Shinohara
authors.forename: Keizo
authors.initials: K
authors.lastname: Fujiwara
authors.forename: Yosuke
authors.initials: Y
authors.lastname: Tona
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Yamazaki
authors.forename: Yuji
authors.initials: Y
authors.lastname: Kanazawa
authors.forename: Risa
authors.initials: R
authors.lastname: Kurihara
authors.forename: Yukihiro
authors.initials: Y
authors.lastname: Imai
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Naito
mesh_terms: D000368:Aged; D005189:False Positive Reactions; D005260:Female; D019788:Fluorodeoxyglucose F18; D006099:Granuloma / Q000000981:diagnostic imaging / Q000209:etiology*; D006258:Head and Neck Neoplasms / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D064847:Multimodal Imaging; D013517:Otorhinolaryngologic Surgical Procedures / Q000009:adverse effects*; D049268:Positron-Emission Tomography; D011183:Postoperative Complications / Q000000981:diagnostic imaging*; D013537:Sutures / Q000009:adverse effects*; D014057:Tomography, X-Ray Computed
chemical_list: D019788:Fluorodeoxyglucose F18