title: Bioprosthesis valve replacement in dogs with congenital tricuspid valve dysplasia: technique and outcome.
abstract: OBJECTIVE
  To describe the surgical technique and report outcome of dogs undergoing bioprosthesis valve replacement for severe tricuspid regurgitation (TR) secondary to congenital tricuspid valve dysplasia (TVD).
  
  
  METHODS
  Twelve client-owned dogs (19-43 kg) with TVD underwent tricuspid valve replacement with a bovine pericardial or porcine aortic bioprosthesis with the aid of cardiopulmonary bypass. Anticoagulation with warfarin was maintained for 3 months after surgery and then discontinued.
  
  
  RESULTS
  Ten of 12 (83.3%) dogs survived surgery and were discharged from the hospital. Seven dogs were alive with complete resolution of TR for a median period of 48 months (range 1-66 months) after surgery. Two dogs underwent euthanasia because of bioprosthesis failure due to inflammatory pannus at 10 and 13 months after surgery. Two dogs experienced valve thrombosis that was resolved by tissue plasminogen activator. One dog developed suspected endocarditis after surgery that was resolved with antibiotics. Serious cardiac complications included atrial fibrillation and flutter, right-to-left shunt through an uncorrected patent foramen ovale, complete atrioventricular block, and sudden cardiac arrest. Postoperative atrial fibrillation or flutter did not occur in 7 dogs treated prophylactically with oral amiodarone before surgery.
  
  
  CONCLUSIONS
  Curative intermediate-term outcomes are possible in dogs undergoing open tricuspid valve replacement with a bioprosthesis. Prosthesis-related complications include inflammatory pannus, thrombosis, and endocarditis. Postoperative atrial fibrillation or flutter can be reduced or prevented by prophylactic preoperative treatment with amiodarone. Several identified complications are avoidable or can be reduced with increased awareness and experience with these techniques.
authors.affiliation: Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO 80523-1678, USA.
authors.forename: Shiori
authors.initials: S
authors.lastname: Arai
authors.forename: Leigh G
authors.initials: LG
authors.lastname: Griffiths
authors.forename: Khursheed
authors.initials: K
authors.lastname: Mama
authors.forename: Timothy B
authors.initials: TB
authors.lastname: Hackett
authors.forename: Eric
authors.initials: E
authors.lastname: Monnet
authors.forename: June A
authors.initials: JA
authors.lastname: Boon
authors.forename: Leslie
authors.initials: L
authors.lastname: Carter
authors.forename: E Christopher
authors.initials: EC
authors.lastname: Orton
mesh_terms: D000818:Animals; D001705:Bioprosthesis / Q000662:veterinary*; D004283:Dog Diseases / Q000151:congenital / Q000601:surgery*; D004285:Dogs; D005260:Female; D006350:Heart Valve Prosthesis / Q000662:veterinary*; D019918:Heart Valve Prosthesis Implantation / Q000379:methods / Q000662:veterinary*; D008297:Male; D011183:Postoperative Complications / Q000453:epidemiology / Q000662:veterinary; D016896:Treatment Outcome; D014261:Tricuspid Valve / Q000002:abnormalities / Q000601:surgery*; D014262:Tricuspid Valve Insufficiency / Q000151:congenital / Q000601:surgery / Q000662:veterinary*