title: Nasal polyps: pathogenesis and treatment implications.
abstract: Nasal polyps (NPs) represent a common clinical end point for a myriad of inflammatory disease processes involving the paranasal sinuses. Chronic rhinosinusitis is the most common cause for NPs, but not all NPs are created equally. This article outlines the current understanding of pathogenesis in nasal polyposis and discusses the implications on therapy.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Eastern Virginia Medical School, Norfolk, VA 23507, USA.
authors.forename: Michael A
authors.initials: MA
authors.lastname: DeMarcantonio
authors.forename: Joseph K
authors.initials: JK
authors.lastname: Han
mesh_terms: D055963:Asthma, Aspirin-Induced / Q000150:complications; D002908:Chronic Disease; D003550:Cystic Fibrosis / Q000150:complications; D016207:Cytokines / Q000502:physiology; D004768:Enterotoxins / Q000502:physiology; D004802:Eosinophilia / Q000150:complications; D006801:Humans; D009298:Nasal Polyps / Q000209:etiology* / Q000628:therapy*; D012220:Rhinitis / Q000150:complications; D012852:Sinusitis / Q000150:complications; D013211:Staphylococcus aureus / Q000378:metabolism; D013601:T-Lymphocytes / Q000502:physiology; D053773:Transforming Growth Factor beta1 / Q000502:physiology
chemical_list: D016207:Cytokines; D004768:Enterotoxins; D053773:Transforming Growth Factor beta1