title: [Safety of preoperative oral rehydration therapy].
abstract: BACKGROUND
  OS-1 is an oral rehydration solution that conforms with the principles of oral rehydration therapy. It may be useful for preoperative fluid management of surgical patients. While intake of clear fluids 2 hours before surgery is considered safe, it is not known if the same applies to OS-1. We therefore investigated the safety of OS-1 for preoperative patients as compared with clear fluids.
  
  
  METHODS
  First, eight healthy adult volunteers were studied in a crossover manner. Volunteers ingested 500 ml of OS-1 or water (clear fluid). Gastric emptying time was measured using gastric ultrasonography. Gastric antral area as measured by ultrasonography correlates well with gastric volume in a close-to-linear manner. Next, we measured gastric volume of elective surgical patients who had drunk OS-1 until two hours before the induction of anesthesia.
  
  
  RESULTS
  Gastric emptying time did not differ between OS-1 and water. The stomach was emptied 30 minutes after ingestion of both OS-1 and water. The fasting stomach was identified in all patients who had drunk OS-1 before surgery.
  
  
  CONCLUSIONS
  We concluded that allowing elective surgical patients to drink OS-1 until two hours before anesthesia did not affect the volume of gastric contents.
authors.affiliation: Department of Anesthesia, Social Insurance Funabashi Central Hospital, Funabashi 273-8556.
authors.forename: Fumiaki
authors.initials: F
authors.lastname: Mimura
authors.forename: Yasuyoshi
authors.initials: Y
authors.lastname: Sakurai
authors.forename: Michiko
authors.initials: M
authors.lastname: Uchida
authors.forename: Junko
authors.initials: J
authors.lastname: Aiba
authors.forename: Midori
authors.initials: M
authors.lastname: Yamaguchi
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D005440:Fluid Therapy; D005746:Gastric Emptying; D006801:Humans; D008297:Male; D011300:Preoperative Care; D012449:Safety; D013997:Time Factors