title: Are we ready for a new look at the diagnosis of premature rupture of membranes?
abstract: Premature rupture of membranes is a significant contributor to preterm birth with its associated short- and long-term complications. The absence of a standard approach to its management places a burden on the clinicians' ability to promptly and accurately diagnose premature rupture of membranes. For the last half century, there have been no significant changes in the way premature ruptured membranes is diagnosed. With the advent of newer, amniotic fluid-specific, noninvasive, and accurate markers, there is an opportunity to update the diagnosis of premature rupture of membranes.
authors.affiliation: Wayne State University School of Medicine, Dearborn, MI, USA. marionaf@oakwood.org
authors.forename: Federico G
authors.initials: FG
authors.lastname: Mariona
authors.forename: Lluis
authors.initials: L
authors.lastname: Cabero
mesh_terms: D000653:Amniotic Fluid / Q000737:chemistry; D004632:Emergency Medical Services / Q000706:statistics & numerical data; D005260:Female; D005322:Premature Rupture of Fetal Membranes / Q000175:diagnosis* / Q000453:epidemiology / Q000628:therapy; D006801:Humans; D007752:Obstetric Labor, Premature / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy; D010360:Patient Transfer / Q000706:statistics & numerical data; D011247:Pregnancy; D011296:Prenatal Diagnosis / Q000379:methods* / Q000592:standards* / Q000706:statistics & numerical data; D012680:Sensitivity and Specificity