title: A 12-year-old chinese girl with Cushing syndrome and virilization due to adrenocortical carcinoma.
abstract: A Chinese adolescent girl presented with secondary amenorrhea. During follow-up, she gradually developed Cushingoid features and virilization. After a series of endocrine investigations, including urinary steroid profiling, a diagnosis of adrenocortical carcinoma was made. The treatment and prognosis of the disease are discussed.
authors.affiliation: Department of Pediatrics and Adolescent Medicine, Tuen Mun Hospital, New Territories, Hong Kong, PR China. Imwong888@hotmail.com
authors.forename: Lap Ming
authors.initials: LM
authors.lastname: Wong
authors.forename: Chak Ho
authors.initials: CH
authors.lastname: Li
authors.forename: On Kei Angel
authors.initials: OK
authors.lastname: Chan
authors.forename: Chi Chung
authors.initials: CC
authors.lastname: Shek
authors.forename: Ngai Shan
authors.initials: NS
authors.lastname: Kwong
mesh_terms: D000306:Adrenal Cortex Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000235:genetics; D000315:Adrenalectomy; D018268:Adrenocortical Carcinoma / Q000150:complications / Q000175:diagnosis* / Q000235:genetics; D000568:Amenorrhea / Q000175:diagnosis / Q000209:etiology / Q000235:genetics; D002648:Child; D003480:Cushing Syndrome / Q000175:diagnosis* / Q000209:etiology / Q000235:genetics; D004200:Diseases in Twins; D005260:Female; D016158:Genes, p53; D006728:Hormones / Q000097:blood / Q000652:urine; D006801:Humans; D009154:Mutation; D014057:Tomography, X-Ray Computed; D014770:Virilism / Q000175:diagnosis* / Q000209:etiology / Q000235:genetics
chemical_list: D006728:Hormones