title: Quantification of intraventricular hemorrhage with electrical impedance tomography using a spherical model.
abstract: We have developed a robust EEG-based current pattern which shows promise for the detection of intraventricular hemorrhage (IVH) in neonates. Our reconstructions to date are based on a layered spherical head model. In this study, the current pattern was used to gather data from three realistic-shaped neonatal head models and a physical phantom based on one of these models. We found that a sensitivity matrix calculated from a spherical model gave us satisfactory reconstructions in terms of both image quality and quantification. Incorporating correct geometry information into the forward model improved image quality. However, it did not improve quantification accuracy. The results indicate that using a spherical matrix may be a more practical choice for monitoring IVH volumes in neonates for whom patient-specific models are not available.
authors.affiliation: Department of Biomedical Engineering, University of Florida, Box 116131, Gainesville, FL 32601, USA. rsadleir@bme.ufl.edu
authors.forename: T
authors.initials: T
authors.lastname: Tang
authors.forename: R J
authors.initials: RJ
authors.lastname: Sadleir
mesh_terms: D017097:Electric Impedance; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D007231:Infant, Newborn; D020300:Intracranial Hemorrhages / Q000175:diagnosis* / Q000473:pathology; D008953:Models, Anatomic; D014054:Tomography / Q000379:methods*