title: Research progresses in the pathogenesis of anaplastic large cell lymphoma.
abstract: Anaplastic large cell lymphoma (ALCL) is a distinct subset of T-cell non-Hodgkin's lymphoma. As a consequence of its low incidence, general pathogenic consideration of ALCL is lacking. In this review, we summarize the pathogenesis, epidemiology, clinical manifestations, and treatment of ALCL, so as to better understand key stages of the development of this disease and provide valuable information for future treatment.
authors.affiliation: Department of Hematology, the First Affiliated Hospital of Soochow University, Jiangsu 215006, People's Republic of China.
authors.forename: Xiao-Lan
authors.initials: XL
authors.lastname: Shi
authors.forename: Xiao-Wen
authors.initials: XW
authors.lastname: Tang
authors.forename: De-Pei
authors.initials: DP
authors.lastname: Wu
mesh_terms: D000077548:Anaplastic Lymphoma Kinase; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D003131:Combined Modality Therapy; D006801:Humans; D017730:Ki-1 Antigen / Q000378:metabolism*; D017728:Lymphoma, Large-Cell, Anaplastic / Q000453:epidemiology / Q000209:etiology* / Q000378:metabolism / Q000628:therapy; D011878:Radiotherapy; D020794:Receptor Protein-Tyrosine Kinases / Q000378:metabolism*; D033581:Stem Cell Transplantation
chemical_list: D017730:Ki-1 Antigen; D000077548:Anaplastic Lymphoma Kinase; D020794:Receptor Protein-Tyrosine Kinases