title: Evidence for the optical signalling of changes in bicarbonate concentration within the mitochondrial region of living cells.
abstract: Image and spectral intensity from bicarbonate-selective europium(III) probes localised in the mitochondria of cells is modulated reversibly by variation of external pCO(2), and is suppressed by addition of the carbonic anhydrase inhibitor, acetazolomide.
authors.affiliation: Department of Chemistry, Durham University, South Road, Durham, UK DH1 3LE.
authors.forename: David G
authors.initials: DG
authors.lastname: Smith
authors.forename: Ga-lai
authors.initials: GL
authors.lastname: Law
authors.forename: Benjamin S
authors.initials: BS
authors.lastname: Murray
authors.forename: Robert
authors.initials: R
authors.lastname: Pal
authors.forename: David
authors.initials: D
authors.lastname: Parker
authors.forename: Ka-Leung
authors.initials: KL
authors.lastname: Wong
mesh_terms: D000818:Animals; D001639:Bicarbonates / Q000378:metabolism*; D001692:Biological Transport; D002460:Cell Line; D002470:Cell Survival; D006801:Humans; D008853:Microscopy; D008928:Mitochondria / Q000378:metabolism*; D055620:Optical Phenomena
chemical_list: D001639:Bicarbonates