title: First-ever, door-to-door cross-sectional representative study in Prey Veng province (Cambodia).
abstract: OBJECTIVE
  To estimate the lifetime prevalence of epilepsy in Prey Veng province (Cambodia).
  
  
  METHODS
  Door-to-door screening was performed using a random cluster survey whereby all people >1 year of age were screened for epilepsy by using a validated and standardized questionnaire for epilepsy in tropical countries. Suspected epilepsy patients identified by the questionnaire were revisited and examined by epileptologists. The confirmation of epilepsy was based on an in-depth clinical examination. Electroencephalograms were recorded at the community dispensary.
  
  
  RESULTS
  Five hundred three potential epilepsy cases were identified from 16,510 screened subjects, and 96 were diagnosed to have epilepsy. An overall prevalence of 5.8 per 1,000 [95% confidence interval (CI) 4.6-7.0 per 1,000] was obtained. Generalized epilepsy (76%) was more common than partial epilepsy (12.5%). Three cases were of generalized myoclonic epilepsy (3.1%) and one case each (1.0%) were of absence and olfactory partial epilepsy. Six cases (5.2%) had more than one seizure type [one case with absence + generalized tonic-clonic (GTC), one case each with GTC + partial seizures with secondary generalization and absence + generalized myoclonic seizures and absence + simple partial seizures, and two cases with GTC + complex partial seizures]. Electroencephalography (EEG) studies revealed spike and wave discharges in 43.8%, focal spikes in 21.0%, generalized slow waves in 19.2%, and generalized slowing of background in 15.7%.
  
  
  CONCLUSIONS
  This is the first population-based study in Cambodia that had epilepsy as a primary objective, and compared to Western and neighboring countries it shows a lower prevalence.
authors.affiliation: University of Limoges, IFR 145 GEIST, Institute of Tropical Neurology (EA 3174), Limoges, France. preux@unilim.fr
authors.forename: Pierre-Marie
authors.initials: PM
authors.lastname: Preux
authors.forename: Kimly
authors.initials: K
authors.lastname: Chea
authors.forename: Hun
authors.initials: H
authors.lastname: Chamroeun
authors.forename: Devender
authors.initials: D
authors.lastname: Bhalla
authors.forename: Mey
authors.initials: M
authors.lastname: Vannareth
authors.forename: Pierre
authors.initials: P
authors.lastname: Huc
authors.forename: Chan
authors.initials: C
authors.lastname: Samleng
authors.forename: Mireille
authors.initials: M
authors.lastname: Cayreyre
authors.forename: Daniel
authors.initials: D
authors.lastname: Gérard
authors.forename: Michel
authors.initials: M
authors.lastname: Dumas
authors.forename: Sophal
authors.initials: S
authors.lastname: Oum
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D017668:Age of Onset; D000368:Aged; D002160:Cambodia / Q000453:epidemiology; D002648:Child; D003430:Cross-Sectional Studies / Q000379:methods / Q000706:statistics & numerical data; D003625:Data Collection; D004827:Epilepsy / Q000175:diagnosis / Q000453:epidemiology*; D005260:Female; D006306:Health Surveys / Q000379:methods; D006801:Humans; D008297:Male; D008403:Mass Screening / Q000379:methods; D008875:Middle Aged; D015995:Prevalence; D011795:Surveys and Questionnaires