title: Continuous production of functionalized polymer particles employing the phase separation in polymer blend films.
abstract: This study reports a continuous prepartion of spherical or hemispherical polymer particles simply utilizing the phase separation in polymer blend films during the coating process. We took an advantage of the strong phase separation between a water-soluble crystalline polymer as a matrix and hydrophobic polymers as minor components. We demonstrated the prepartion of water-soluble polystyrene (PS) particles, nitrilotriacetic acid (NTA)-functionalized PS particles for protein separation, and semiconducting poly(3-hexylthiophene) (P3HT) particles. The sizes of the particles could be controlled by adjusting the film thickness and weight fraction of the minor component polymers in the blend film. It provides a simple facile way to prepare polymer particles in a continous process.
authors.affiliation: Department of Materials Science and Engineering, Yonsei University, 134 Shinchon-dong, Seoul 120-749, Korea.
authors.forename: ChooJin
authors.initials: C
authors.lastname: Park
authors.forename: Dong Choon
authors.initials: DC
authors.lastname: Hyun
authors.forename: Min-Cheol
authors.initials: MC
authors.lastname: Lim
authors.forename: Su-Jeong
authors.initials: SJ
authors.lastname: Kim
authors.forename: Young-Rok
authors.initials: YR
authors.lastname: Kim
authors.forename: Hyun-Jong
authors.initials: HJ
authors.lastname: Paik
authors.forename: Unyong
authors.initials: U
authors.lastname: Jeong
mesh_terms: D049452:Green Fluorescent Proteins / Q000302:isolation & purification; D057927:Hydrophobic and Hydrophilic Interactions; D009571:Nitrilotriacetic Acid / Q000737:chemistry; D010316:Particle Size; D011108:Polymers / Q000138:chemical synthesis* / Q000737:chemistry; D011137:Polystyrenes / Q000737:chemistry*; D052616:Solid Phase Extraction / Q000295:instrumentation*; D013499:Surface Properties
chemical_list: D011108:Polymers; D011137:Polystyrenes; D049452:Green Fluorescent Proteins; D009571:Nitrilotriacetic Acid