title: Conia-ene annulation of the α-cyano β-TMS-capped alkynyl cycloalkanone system and its synthetic application.
abstract: Under catalysis with ZnI(2), an effective annulation process of ω-silylacetylenic α-cyano ketones, leading to the formation of various bicyclic frameworks characterized with a TMS-containing methylenecyclopentane ring, has been developed.
authors.affiliation: Department of Chemistry, National Tsing Hua University, Hsinchu, Taiwan 30013, ROC.
authors.forename: Chih-Lung
authors.initials: CL
authors.lastname: Chin
authors.forename: Cheng-Feng
authors.initials: CF
authors.lastname: Liao
authors.forename: Hsing-Jang
authors.initials: HJ
authors.lastname: Liu
authors.forename: Ying-Chieh
authors.initials: YC
authors.lastname: Wong
authors.forename: Ming-Tsang
authors.initials: MT
authors.lastname: Hsieh
authors.forename: Prashanth K
authors.initials: PK
authors.lastname: Amancha
authors.forename: Chun-Ping
authors.initials: CP
authors.lastname: Chang
authors.forename: Kak-Shan
authors.initials: KS
authors.lastname: Shia
mesh_terms: D000473:Alkanes / Q000138:chemical synthesis*; D000480:Alkynes / Q000737:chemistry*; D003486:Cyanides / Q000737:chemistry*; D003500:Cyclization; D007659:Ketones; D015394:Molecular Structure; D014297:Trimethylsilyl Compounds / Q000737:chemistry*
chemical_list: D000473:Alkanes; D000480:Alkynes; D003486:Cyanides; D007659:Ketones; D014297:Trimethylsilyl Compounds