title: [Medical treatments of endocrine-sensitive Her-2 negative breast cancers: a review].
abstract: New molecular classification is one of the cornerstones of current and future progress in research and patient care for breast carcinoma. For the larger hormone-receptor positive and Her-2 negative subgroup, which concerns 75% of the patients, endocrine therapy and chemotherapy may be considered. Looking toward new-targeted therapies, this paper reviews the current use of these two treatment modalities in adjuvant, neoadjuvant and metastatic settings of this disease.
authors.affiliation: Institut Bergonié, département d'oncologie médicale, Bordeaux Cedex, France. debled@bergonie.org
authors.forename: Marc
authors.initials: M
authors.lastname: Debled
authors.forename: Florence
authors.initials: F
authors.lastname: Dalenc
authors.forename: Louis
authors.initials: L
authors.lastname: Mauriac
authors.forename: Etienne
authors.initials: E
authors.lastname: Brain
mesh_terms: D000911:Antibodies, Monoclonal / Q000627:therapeutic use; D061067:Antibodies, Monoclonal, Humanized; D018931:Antineoplastic Agents, Hormonal / Q000009:adverse effects / Q000627:therapeutic use*; D047072:Aromatase Inhibitors / Q000009:adverse effects / Q000627:therapeutic use*; D000068258:Bevacizumab; D001943:Breast Neoplasms / Q000737:chemistry / Q000188:drug therapy* / Q000517:prevention & control; D017024:Chemotherapy, Adjuvant / Q000379:methods; D004334:Drug Administration Schedule; D005260:Female; D007987:Gonadotropin-Releasing Hormone / Q000819:agonists / Q000037:antagonists & inhibitors; D006801:Humans; D008593:Menopause; D009363:Neoplasm Proteins / Q000378:metabolism; D009364:Neoplasm Recurrence, Local / Q000517:prevention & control; D018719:Erb-b2 Receptor Tyrosine Kinases / Q000378:metabolism; D013629:Tamoxifen / Q000009:adverse effects / Q000627:therapeutic use
chemical_list: D000911:Antibodies, Monoclonal; D061067:Antibodies, Monoclonal, Humanized; D018931:Antineoplastic Agents, Hormonal; D047072:Aromatase Inhibitors; D000068258:Bevacizumab; D007987:Gonadotropin-Releasing Hormone; D009363:Neoplasm Proteins; D018719:Erb-b2 Receptor Tyrosine Kinases; D013629:Tamoxifen