title: Anticomplement activity of isolated compounds from Artemisia montana.
abstract: The study evaluated the anticomplement activity from isolated compounds from Artemisia montana (Nakai) Pamp. from South Korea on the classical pathway. In a previous work, A. montana (Nakai) Pamp. chloroform extracts showed inhibitory activity against complement system. The chromatographic separation of a chloroform chloride extract of A. montana (Nakai) Pamp. led to the isolation of four compounds. Their structures were characterized to be ezoartemin, yamayomoginin, ezomontanin and 11,13-dihydroezomontanin by spectroscopic data. This is the first report of anticomplement activity of isolated compounds from A. montana (Nakai) Pamp.
authors.affiliation: Department of Medicinal Biotechnology, College of Natural Resources and Life Science, Dong-A University, Busan, South Korea. himun68@dau.ac.kr
authors.forename: Hyung-In
authors.initials: HI
authors.lastname: Moon
authors.forename: Seil
authors.initials: S
authors.lastname: Jung
authors.forename: Young-Choon
authors.initials: YC
authors.lastname: Lee
authors.forename: Jai-Heon
authors.initials: JH
authors.lastname: Lee
mesh_terms: D000328:Adult; D000818:Animals; D019306:Artemisia / Q000737:chemistry*; D003171:Complement Pathway, Classical / Q000187:drug effects*; D003165:Complement System Proteins / Q000737:chemistry*; D006801:Humans; D008297:Male; D012756:Sheep
chemical_list: D003165:Complement System Proteins