title: Adherence to CLSI recommendations for testing of Staphylococcus aureus isolates in Louisiana hospitals: report of a clinical failure and results of a questionnaire study.
abstract: We report a case of failure of clindamycin therapy due to inducible clindamycin resistance. We surveyed and found that only 52% of reporting hospitals in the state of Louisiana were performing the D test for inducible clindamycin resistance according to guidelines recommended by the Clinical and Laboratory Standards Institute (formerly the National Committee for Clinical Laboratory Standards).
authors.affiliation: Department of Pediatrics, Louisiana State University Health Sciences Center at Shreveport, 1501 Kings Hwy., Ste. 5-303, Shreveport, LA 71130, USA.
authors.forename: Kamakshya P
authors.initials: KP
authors.lastname: Patra
authors.forename: John A
authors.initials: JA
authors.lastname: Vanchiere
authors.forename: Joseph A
authors.initials: JA
authors.lastname: Bocchini
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology* / Q000627:therapeutic use; D002648:Child; D002981:Clindamycin / Q000494:pharmacology* / Q000627:therapeutic use; D005260:Female; D019983:Guideline Adherence / Q000706:statistics & numerical data*; D006761:Hospitals; D006801:Humans; D008145:Louisiana; D008826:Microbial Sensitivity Tests / Q000592:standards; D013203:Staphylococcal Infections / Q000188:drug therapy / Q000382:microbiology*; D013211:Staphylococcus aureus / Q000187:drug effects*; D011795:Surveys and Questionnaires; D017211:Treatment Failure
chemical_list: D000900:Anti-Bacterial Agents; D002981:Clindamycin