title: Caffeic acid phenethyl ester (CAPE): correlation of structure and antioxidant properties.
abstract: Caffeic acid phenethyl ester (CAPE), a plant polyphenolic concentrated in honeybee propolis, has been found to be biologically active in a variety of pathways. The aim of this study was to determine the antioxidant activity of CAPE using different methods such as total antioxidant activity by the thiocyanate method, 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulphonic acid radicals, 1,1-diphenyl-2-picryl-hydrazyl free radicals, N,N-dimethyl-p-phenylenediamine dihydrochloride radicals and superoxide anion radicals scavenging activities, reducing power and ferrous ions (Fe(2+)) chelating activities. CAPE showed 97.9% inhibition on lipid peroxidation of linoleic acid emulsion. On the other hand, butylated hydroxyanisole, butylated hydroxytoluene, α-tocopherol and trolox indicated an inhibition of 87.3, 97.6, 75.3 and 90.3% on peroxidation in the same system, respectively.
authors.affiliation: Department of Chemistry, Faculty of Sciences, Atatürk University, Erzurum, Turkey.
authors.forename: Hülya
authors.initials: H
authors.lastname: Göçer
authors.forename: Ilhami
authors.initials: I
authors.lastname: Gülçin
mesh_terms: D000975:Antioxidants / Q000494:pharmacology*; D002109:Caffeic Acids / Q000494:pharmacology*; D004655:Emulsions; D019787:Linoleic Acid / Q000378:metabolism*; D015227:Lipid Peroxidation / Q000187:drug effects*; D010626:Phenylethyl Alcohol / Q000031:analogs & derivatives* / Q000494:pharmacology; D010936:Plant Extracts / Q000494:pharmacology*; D059808:Polyphenols / Q000494:pharmacology*; D011429:Propolis / Q000737:chemistry*
chemical_list: D000975:Antioxidants; D002109:Caffeic Acids; D004655:Emulsions; D010936:Plant Extracts; D059808:Polyphenols; D011429:Propolis; D019787:Linoleic Acid; C055494:caffeic acid phenethyl ester; D010626:Phenylethyl Alcohol