title: Sarcopenia with limited mobility: an international consensus.
abstract: A consensus conference convened by the Society of Sarcopenia, Cachexia and Wasting Disorders has concluded that "Sarcopenia, ie, reduced muscle mass, with limited mobility" should be considered an important clinical entity and that most older persons should be screened for this condition. "Sarcopenia with limited mobility" is defined as a person with muscle loss whose walking speed is equal to or less than 1 m/s or who walks less than 400 m during a 6-minute walk, and who has a lean appendicular mass corrected for height squared of 2 standard deviations or more below the mean of healthy persons between 20 and 30 years of age of the same ethnic group. The limitation in mobility should not clearly be a result of otherwise defined specific diseases of muscle, peripheral vascular disease with intermittent claudication, central and peripheral nervous system disorders, or cachexia. Clinically significant interventions are defined as an increase in the 6-minute walk of at least 50 meters or an increase of walking speed of at least 0.1 m/s.
authors.affiliation: Division of Geriatric Medicine, Saint Louis University School of Medicine and GRECC, VA Medical Center, St. Louis, MO 63104, USA. morley@slu.edu
authors.forename: John E
authors.initials: JE
authors.lastname: Morley
authors.forename: Angela Marie
authors.initials: AM
authors.lastname: Abbatecola
authors.forename: Josep M
authors.initials: JM
authors.lastname: Argiles
authors.forename: Vickie
authors.initials: V
authors.lastname: Baracos
authors.forename: Juergen
authors.initials: J
authors.lastname: Bauer
authors.forename: Shalender
authors.initials: S
authors.lastname: Bhasin
authors.forename: Tommy
authors.initials: T
authors.lastname: Cederholm
authors.forename: Andrew J Stewart
authors.initials: AJ
authors.lastname: Coats
authors.forename: Steven R
authors.initials: SR
authors.lastname: Cummings
authors.forename: William J
authors.initials: WJ
authors.lastname: Evans
authors.forename: Kenneth
authors.initials: K
authors.lastname: Fearon
authors.forename: Luigi
authors.initials: L
authors.lastname: Ferrucci
authors.forename: Roger A
authors.initials: RA
authors.lastname: Fielding
authors.forename: Jack M
authors.initials: JM
authors.lastname: Guralnik
authors.forename: Tamara B
authors.initials: TB
authors.lastname: Harris
authors.forename: Akio
authors.initials: A
authors.lastname: Inui
authors.forename: Kamyar
authors.initials: K
authors.lastname: Kalantar-Zadeh
authors.forename: Bridget-Anne
authors.initials: BA
authors.lastname: Kirwan
authors.forename: Giovanni
authors.initials: G
authors.lastname: Mantovani
authors.forename: Maurizio
authors.initials: M
authors.lastname: Muscaritoli
authors.forename: Anne B
authors.initials: AB
authors.lastname: Newman
authors.forename: Filippo
authors.initials: F
authors.lastname: Rossi-Fanelli
authors.forename: Giuseppe M C
authors.initials: GM
authors.lastname: Rosano
authors.forename: Ronenn
authors.initials: R
authors.lastname: Roubenoff
authors.forename: Morris
authors.initials: M
authors.lastname: Schambelan
authors.forename: Gerald H
authors.initials: GH
authors.lastname: Sokol
authors.forename: Thomas W
authors.initials: TW
authors.lastname: Storer
authors.forename: Bruno
authors.initials: B
authors.lastname: Vellas
authors.forename: Stephan
authors.initials: S
authors.lastname: von Haehling
authors.forename: Shing-Shing
authors.initials: SS
authors.lastname: Yeh
authors.forename: Stefan D
authors.initials: SD
authors.lastname: Anker
mesh_terms: D000368:Aged; D005260:Female; D006801:Humans; D038622:Internationality; D008297:Male; D008875:Middle Aged; D051346:Mobility Limitation; D018482:Muscle, Skeletal / Q000502:physiology; D055948:Sarcopenia / Q000517:prevention & control*