title: [Usefulness of 18F-FDG PET-CT in the presurgical assessment of malignant pleural mesothelioma treated with neoadjuvant chemotherapy].
abstract: Malignant pleural mesothelioma is a relatively rare, but highly aggressive, tumor, associated to exposure to asbestos, with a life expectancy between 9 and 17 months. Chest pain and dyspnea are the most frequent symptoms. The most commonly used therapy is surgery accompanied by chemotherapy. Preoperative assessment, after chemotherapy, has been done using magnetic resonance imaging and computed tomography (CT). However, these techniques cannot predict early response to therapy, because of the slow structural change of the tumor. The aim of this case report is to review and learn about the growing use of PET-CT imaging with (18)F-FDG in the preoperative staging of malignant pleural mesothelioma and its influence in selecting the most appropriate type of surgery.
authors.affiliation: Servicio de Medicina Nuclear, Hospital General Universitario Gregorio Marañón, Madrid, España. orcajojavier@hotmail.com
authors.forename: J
authors.initials: J
authors.lastname: Orcajo Rincón
authors.forename: J C
authors.initials: JC
authors.lastname: Alonso Farto
authors.forename: A
authors.initials: A
authors.lastname: Rotger Regi
authors.forename: R
authors.initials: R
authors.lastname: Hernández Pérez
authors.forename: A M
authors.initials: AM
authors.lastname: Hualde
authors.forename: V
authors.initials: V
authors.lastname: Pérez Aradas
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002945:Cisplatin / Q000008:administration & dosage; D003131:Combined Modality Therapy; D005462:Fluorine Radioisotopes; D019788:Fluorodeoxyglucose F18; D005971:Glutamates / Q000008:administration & dosage; D006147:Guanine / Q000008:administration & dosage / Q000031:analogs & derivatives; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D008654:Mesothelioma / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000556:secondary / Q000601:surgery; D008875:Middle Aged; D064847:Multimodal Imaging; D020360:Neoadjuvant Therapy; D000068437:Pemetrexed; D010997:Pleural Neoplasms / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000601:surgery; D049268:Positron-Emission Tomography; D011300:Preoperative Care; D019275:Radiopharmaceuticals; D014057:Tomography, X-Ray Computed; D047368:Tumor Burden
chemical_list: D005462:Fluorine Radioisotopes; D005971:Glutamates; D019275:Radiopharmaceuticals; D000068437:Pemetrexed; D019788:Fluorodeoxyglucose F18; D006147:Guanine; D002945:Cisplatin