title: The association of gamma-glutamyltransferase and C-reactive protein with IFG/IGT in Chinese adults in Qingdao, China.
abstract: BACKGROUND
  Serum gamma-glutamyltransferase (GGT) and C-reactive protein(CRP) have been previously shown to be associated with impaired fasting glucose/impaired glucose tolerance (IFG/IGT), but such an association has not been well verified, and is examined in a non-diabetic Chinese population.
  
  
  METHODS
  A population-based cross-sectional study was conducted in 2006 in Qingdao, China. Data of 1143 men and 1689 women aged 35-74 years and free of diabetes at baseline were analyzed. Multivariable logistic regression analysis was performed to estimate the odds ratio (OR) and its 95% confidence interval (CI).
  
  
  RESULTS
  Compared with the lowest quartile, the ORs (95%CI) for IFG/IGT corresponding to the highest quartile were 0.89(0.61,1.28) in men and 0.87(0.64,1.18) in women for CRP and 2.12(1.40,3.38) and 1.87(1.32,2.62) for GGT, when the two were fitted simultaneously in a model adjusting for age, school years, alcohol-drinking, smoking, family history of diabetes, systolic blood pressure, waist circumference, triglycerides and high-density lipoprotein.
  
  
  CONCLUSIONS
  The elevated GGT, but not CRP, was independently associated with the presence of the IFG/IGT in both genders in this Chinese population.
authors.affiliation: Department of Nutrition and Food Hygiene, Medical College of Qingdao University, Qingdao, China.
authors.forename: Jianping
authors.initials: J
authors.lastname: Sun
authors.forename: J
authors.initials: J
authors.lastname: Ren
authors.forename: Z C
authors.initials: ZC
authors.lastname: Pang
authors.forename: W G
authors.initials: WG
authors.lastname: Gao
authors.forename: H R
authors.initials: HR
authors.lastname: Nan
authors.forename: S J
authors.initials: SJ
authors.lastname: Wang
authors.forename: L
authors.initials: L
authors.lastname: Zhang
authors.forename: Q
authors.initials: Q
authors.lastname: Qiao
mesh_terms: D000328:Adult; D000368:Aged; D002097:C-Reactive Protein / Q000378:metabolism*; D002681:China; D002851:Chromatography, High Pressure Liquid; D003430:Cross-Sectional Studies; D005260:Female; D005951:Glucose Tolerance Test; D006801:Humans; D008297:Male; D008875:Middle Aged; D005723:gamma-Glutamyltransferase / Q000378:metabolism*
chemical_list: D002097:C-Reactive Protein; D005723:gamma-Glutamyltransferase