title: Malignancies associated with chronic hepatitis C: case report and review of the literature.
abstract: Hepatocellular carcinoma (HCC) is a well-known consequence of hepatitis C virus (HCV) infection mainly in cirrhotic patients. Associations of other malignancies such as cholangiocellular carcinoma and B-cell malignancies with HCV are less well known. Here we review pathophysiological aspects of malignancies associated with HCV infection. A case report of HCV-related HCC and B-cell lymphoma illustrates the increased risk for HCV-infected patients to develop other malignancies besides HCC.
authors.affiliation: Departments of Internal Medicine, Academic Medical Center, Amsterdam, the Netherlands. a.p.vlaar@amc.uva.nl
authors.forename: A P J
authors.initials: AP
authors.lastname: Vlaar
authors.forename: S T
authors.initials: ST
authors.lastname: Rietdijk
authors.forename: S S
authors.initials: SS
authors.lastname: Zeerleder
authors.forename: T
authors.initials: T
authors.lastname: Boerman
authors.forename: U
authors.initials: U
authors.lastname: Beuers
mesh_terms: D000368:Aged; D006528:Carcinoma, Hepatocellular / Q000209:etiology* / Q000473:pathology / Q000821:virology; D018281:Cholangiocarcinoma / Q000209:etiology / Q000473:pathology / Q000821:virology; D019698:Hepatitis C, Chronic / Q000150:complications*; D006801:Humans; D008113:Liver Neoplasms / Q000209:etiology* / Q000473:pathology / Q000821:virology; D008297:Male; D012307:Risk Factors