title: Detection of Crohn's disease: Comparison of CT and MR enterography without anti-peristaltic agents performed on the same day.
abstract: OBJECTIVE
  To directly compare CT enterography (CTE) and MR enterography (MRE) without antiperistaltic agents.
  
  
  METHODS
  26 patients referred for CTE underwent CTE immediately followed by MRE without use of an anti-peristaltic agent. Each study was evaluated on a 10 point scale for exam quality, level of diagnostic confidence, and presence of Crohn's disease. Kappa analysis was performed to determine the degree of agreement between the CTE and MRE of each patient.
  
  
  RESULTS
  25 patients completed the MRE. The quality of the CTEs was judged as excellent by both readers (reader 1=average 9.5/10, reader 2=average 9.1/10). The quality of the MREs was ranked lower than the CTEs by both readers (reader 1=average 8.9/10, reader 2=average 7.2/10), which was statistically significant (p<0.05). The level of confidence in interpretation was not significantly different between CTE and MRE for reader 1 or 2 (p=0.3). There was substantial agreement between readers for the presence or absence of Crohn's disease on both CTE (kappa=0.75) and MRE (kappa=0.67).
  
  
  CONCLUSIONS
  MR enterography without anti-peristaltic agents results in high diagnostic confidence and excellent agreement for the presence of Crohn's disease.
authors.affiliation: Department of Diagnostic Imaging, Warren Alpert School of Medicine, Brown University, 593 Eddy St., Providence, RI 02903, United States. dgrand@lifespan.org
authors.forename: David J
authors.initials: DJ
authors.lastname: Grand
authors.forename: Michael D
authors.initials: MD
authors.lastname: Beland
authors.forename: Jason T
authors.initials: JT
authors.lastname: Machan
authors.forename: William W
authors.initials: WW
authors.lastname: Mayo-Smith
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000930:Antidiarrheals / Q000008:administration & dosage; D001466:Barium Sulfate; D003287:Contrast Media; D003424:Crohn Disease / Q000175:diagnosis*; D005260:Female; D006801:Humans; D007422:Intestines / Q000000981:diagnostic imaging* / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed / Q000379:methods*; D055815:Young Adult
chemical_list: D000930:Antidiarrheals; D003287:Contrast Media; D001466:Barium Sulfate