title: Behavior outbursts, orofacial dyskinesias, and CSF pleocytosis in a healthy child.
abstract: Anti-N-methyl-D-aspartate (NMDA) receptor encephalitis represents a new category of immune-mediated neurologic disorders. Viral encephalitis is often the presumptive diagnosis because of the acute neurologic changes, cerebrospinal fluid lymphocytic pleocytosis, and occasional hyperthermia. We report here the case of a previously healthy 7-year-old boy with new-onset aggressive behavior, seizure activity, and orofacial dyskinesias with cerebrospinal fluid and serum that tested positive for anti-NMDA receptors.
authors.affiliation: Department of Pediatric Infectious Diseases, Johns Hopkins Medical Institution, 200 N Wolfe St, Suite 3150, Baltimore, MD 21287, USA. ptamma1@jhmi.edu
authors.forename: Pranita D
authors.initials: PD
authors.lastname: Tamma
authors.forename: Allison L
authors.initials: AL
authors.lastname: Agwu
authors.forename: Adam L
authors.initials: AL
authors.lastname: Hartman
mesh_terms: D000374:Aggression; D002648:Child; D002653:Child Behavior Disorders / Q000209:etiology*; D004660:Encephalitis / Q000150:complications* / Q000175:diagnosis* / Q000276:immunology; D006801:Humans; D007964:Leukocytosis / Q000134:cerebrospinal fluid / Q000209:etiology*; D008297:Male; D009069:Movement Disorders / Q000209:etiology*; D016194:Receptors, N-Methyl-D-Aspartate / Q000276:immunology
chemical_list: D016194:Receptors, N-Methyl-D-Aspartate