title: Ultrasound assisted one pot synthesis of imidazole derivatives using diethyl bromophosphate as an oxidant.
abstract: A one pot, three-component condensation of benzoin/benzyl, an aldehyde, and ammonium acetate using diethyl bromophosphate as a mild oxidant is achieved to form trisubstituted imidazole compounds. Under ultrasound irradiation, a smooth condensation occurs to get the 2, 4, 5-triaryl-1H-imidazole compounds in good to excellent yields. The study explores the scope and limitation of diethyl bromophosphate as an oxidant and suggests advantages, viz., simplicity of operation, reduction in time, and an increase in product yields.
authors.affiliation: Department of Chemistry, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad 431 004, India. dnagargoje@gmail.com
authors.forename: Deepak
authors.initials: D
authors.lastname: Nagargoje
authors.forename: Priyanka
authors.initials: P
authors.lastname: Mandhane
authors.forename: Savita
authors.initials: S
authors.lastname: Shingote
authors.forename: Pravin
authors.initials: P
authors.lastname: Badadhe
authors.forename: Charansingh
authors.initials: C
authors.lastname: Gill
mesh_terms: D007093:Imidazoles / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D009943:Organophosphorus Compounds / Q000737:chemistry*; D016877:Oxidants / Q000737:chemistry*; D013237:Stereoisomerism; D014465:Ultrasonics
chemical_list: D007093:Imidazoles; D009943:Organophosphorus Compounds; D016877:Oxidants; C029899:imidazole