title: Comparison of classic and derivative UV spectrophotometric methods for quantification of meloxicam and mefenamic acid in pharmaceutical preparations.
abstract: The methods for quantitative determination of meloxicam and mefenamic acid in pharmaceuticals by classic spectrophotometry - zero order derivative, first and second order derivatives spectrophotometry is described, using "peak - peak" (P-P) and "peak - zero" (P-O) measurements. The calibration curves are linear within the concentration range of 4.0 - 14.0 microg/mL for meloxicam and 14.0 - 24.0 microg/mL for mefenamic acid. The procedure is simple, rapid and the results are reliable.
authors.affiliation: Chair and Department of Medicinal Chemistry, Faculty of Pharmacy, Medical University of Lublin, 4 Jaczewskiego St., 20-090 Lublin, Poland. arkadiusz.pomykalski@umlub.pl
authors.forename: Arkadiusz
authors.initials: A
authors.lastname: Pomykalski
authors.forename: Hanna
authors.initials: H
authors.lastname: Hopkała
mesh_terms: D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000032:analysis*; D002138:Calibration; D008528:Mefenamic Acid / Q000032:analysis*; D000077239:Meloxicam; D015203:Reproducibility of Results; D013056:Spectrophotometry, Ultraviolet / Q000592:standards; D013678:Technology, Pharmaceutical / Q000379:methods* / Q000592:standards; D013843:Thiazines / Q000032:analysis*; D013844:Thiazoles / Q000032:analysis*
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D013843:Thiazines; D013844:Thiazoles; D008528:Mefenamic Acid; D000077239:Meloxicam