title: Molecular genetic and pathogenic characterization of psittacid herpesvirus type 1 isolated from a captive galah (Eolophus roseicapillus) in Japan.
abstract: Psittacid herpesvirus type 1 (PsHV-1) was isolated from a captive galah (Eolophus roseicapillus) in Japan that was suspected of having Pacheco's disease (PD), an acute fatal disease in psittacine birds. PsHV-1 has been classified into four genotypes based on the UL16 gene sequence. In the present study, we investigated the genetic and pathogenic characteristics of the isolated virus, FOY-1, compared with a reference strain, RSL-1. The FOY-1 strain was classified into PsHV-1 genotype 2. The FOY-1 strain was found to be less pathogenic to budgerigars than RSL-1, which was classified as genotype 4 in an in vivo study. This is the first report regarding the classification of originally isolated PsHV-1 in Japan and its characterization by animal infection experiment.
authors.affiliation: Department of Applied Veterinary Sciences, United Graduate School of Veterinary Sciences, Gifu University, Gifu, Japan.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Katoh
authors.forename: Souichi
authors.initials: S
authors.lastname: Yamada
authors.forename: Takayuki
authors.initials: T
authors.lastname: Hagino
authors.forename: Kenji
authors.initials: K
authors.lastname: Ohya
authors.forename: Hiroki
authors.initials: H
authors.lastname: Sakai
authors.forename: Tokuma
authors.initials: T
authors.lastname: Yanai
authors.forename: Toshiaki
authors.initials: T
authors.lastname: Masegi
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Yamaguchi
authors.forename: Hideto
authors.initials: H
authors.lastname: Fukushi
mesh_terms: D018138:Alphaherpesvirinae / Q000235:genetics* / Q000302:isolation & purification / Q000472:pathogenicity; D000818:Animals; D001483:Base Sequence; D001715:Bird Diseases / Q000401:mortality / Q000821:virology*; D046410:Cockatoos / Q000821:virology*; D004279:DNA, Viral / Q000737:chemistry*; D006566:Herpesviridae Infections / Q000401:mortality / Q000662:veterinary* / Q000821:virology; D007564:Japan; D046408:Melopsittacus / Q000821:virology; D008969:Molecular Sequence Data; D010802:Phylogeny
chemical_list: D004279:DNA, Viral