title: Unilateral salpingo-oophorectomy as fertility-sparing surgery for borderline ovarian tumors.
abstract: BACKGROUND
  To investigate recurrence rates and fertility outcomes of patients with borderline ovarian tumors (BOTs) treated with fertility-sparing surgery.
  
  
  METHODS
  This was a retrospective study. All women with BOTs from 2000 to 2006 were evaluated. Clinical outcomes were compared among groups that underwent radical, unilateral salpingo-oophorectomy, or ovarian cystectomy. The effects of clinical characteristics on recurrence were analyzed by independent t test, chi-square test, and Cox proportional hazard model.
  
  
  RESULTS
  After a mean follow-up period of 56.5 months, all 61 patients were alive. Seven (11.5%) had developed disease recurrence, and all were in the fertility-sparing group. Of these, five were in the cystectomy-only group and two in the unilateral salpingo-oophorectomy group. There was significant difference in tumor recurrence rates between the two groups (hazard ratio: 0.26, 95% confidence interval: 0.11-0.61). Nine pregnancies were achieved in six women, resulting in five deliveries
  
  
  CONCLUSIONS
  Fertility-sparing surgery is an acceptable and safe option for women with BOTs who wish to preserve fertility. Unilateral salpingo-oophorectomy must be considered as the first choice.
authors.affiliation: Department of Obstetrics and Gynecology, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.
authors.forename: Hsiao-Wen
authors.initials: HW
authors.lastname: Tsai
authors.forename: Chin-Chu
authors.initials: CC
authors.lastname: Ko
authors.forename: Chang-Ching
authors.initials: CC
authors.lastname: Yeh
authors.forename: Yi-Jen
authors.initials: YJ
authors.lastname: Chen
authors.forename: Nae-Fang
authors.initials: NF
authors.lastname: Twu
authors.forename: Kuan-Chong
authors.initials: KC
authors.lastname: Chao
authors.forename: Ming-Shyen
authors.initials: MS
authors.lastname: Yen
mesh_terms: D000328:Adult; D000368:Aged; D005187:Fallopian Tubes / Q000601:surgery*; D005260:Female; D005298:Fertility; D006801:Humans; D008875:Middle Aged; D009367:Neoplasm Staging; D010048:Ovarian Cysts / Q000601:surgery; D010051:Ovarian Neoplasms / Q000401:mortality / Q000473:pathology / Q000503:physiopathology / Q000601:surgery*; D010052:Ovariectomy; D012189:Retrospective Studies