title: High sensitivity troponin T concentrations in patients undergoing noncardiac surgery: a prospective cohort study.
abstract: OBJECTIVE
  To determine the proportion of noncardiac surgery patients exceeding the published 99th percentile or change criteria with the high sensitivity Troponin T (hs-TnT) assay.
  
  
  METHODS
  We measured hs-TnT preoperatively and postoperatively on days 1, 2 and 3 in 325 adults.
  
  
  RESULTS
  Postoperatively 45% (95% CI: 39-50%) of patients had hs-TnT≥14ng/L and 22% (95% CI:17-26%) had an elevation (≥14ng/L) and change (>85%) in hs-TnT.
  
  
  CONCLUSIONS
  Further research is needed to inform the optimal hs-TnT threshold and change in this setting.
authors.affiliation: McMaster University, 1200 Main Street West, Hamilton, ON, Canada L8N 3Z5. kavsak@hhsc.ca
authors.forename: Peter A
authors.initials: PA
authors.lastname: Kavsak
authors.forename: Mike
authors.initials: M
authors.lastname: Walsh
authors.forename: Sadeesh
authors.initials: S
authors.lastname: Srinathan
authors.forename: Laurel
authors.initials: L
authors.lastname: Thorlacius
authors.forename: Giovanna Lurati
authors.initials: GL
authors.lastname: Buse
authors.forename: Fernando
authors.initials: F
authors.lastname: Botto
authors.forename: Shirley
authors.initials: S
authors.lastname: Pettit
authors.forename: Matthew J
authors.initials: MJ
authors.lastname: McQueen
authors.forename: Stephen A
authors.initials: SA
authors.lastname: Hill
authors.forename: Sabu
authors.initials: S
authors.lastname: Thomas
authors.forename: Marko
authors.initials: M
authors.lastname: Mrkobrada
authors.forename: Pablo
authors.initials: P
authors.lastname: Alonso-Coello
authors.forename: Otavio
authors.initials: O
authors.lastname: Berwanger
authors.forename: Bruce M
authors.initials: BM
authors.lastname: Biccard
authors.forename: George
authors.initials: G
authors.lastname: Cembrowski
authors.forename: Matthew T V
authors.initials: MT
authors.lastname: Chan
authors.forename: Clara K
authors.initials: CK
authors.lastname: Chow
authors.forename: Angeles
authors.initials: A
authors.lastname: de Miguel
authors.forename: Mercedes
authors.initials: M
authors.lastname: Garcia
authors.forename: Michelle M
authors.initials: MM
authors.lastname: Graham
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Jacka
authors.forename: J H
authors.initials: JH
authors.lastname: Kueh
authors.forename: Stephen C H
authors.initials: SC
authors.lastname: Li
authors.forename: Lydia C W
authors.initials: LC
authors.lastname: Lit
authors.forename: Cecília
authors.initials: C
authors.lastname: Martínez-Brú
authors.forename: Prebashini
authors.initials: P
authors.lastname: Naidoo
authors.forename: Peter
authors.initials: P
authors.lastname: Nagele
authors.forename: Rupert M
authors.initials: RM
authors.lastname: Pearse
authors.forename: Reitze N
authors.initials: RN
authors.lastname: Rodseth
authors.forename: Daniel I
authors.initials: DI
authors.lastname: Sessler
authors.forename: Alben
authors.initials: A
authors.lastname: Sigamani
authors.forename: Wojciech
authors.initials: W
authors.lastname: Szczeklik
authors.forename: Maria
authors.initials: M
authors.lastname: Tiboni
authors.forename: Juan Carlos
authors.initials: JC
authors.lastname: Villar
authors.forename: C Y
authors.initials: CY
authors.lastname: Wang
authors.forename: Denis
authors.initials: D
authors.lastname: Xavier
authors.forename: P J
authors.initials: PJ
authors.lastname: Devereaux
mesh_terms: D000368:Aged; D015331:Cohort Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011184:Postoperative Period; D057234:Preoperative Period; D013514:Surgical Procedures, Operative; D020107:Troponin T / Q000097:blood*
chemical_list: D020107:Troponin T