title: Comparison of whole blood and plasma colloid osmotic pressure in healthy dogs.
abstract: OBJECTIVE
  To determine the difference between colloid osmotic pressure (COP) values determined from plasma versus those determined from whole blood.
  
  
  METHODS
  Prospective observational study.
  
  
  METHODS
  University veterinary teaching hospital.
  
  
  METHODS
  Fifty-three healthy dogs.
  
  
  METHODS
  None.
  
  
  RESULTS
  Whole blood and plasma COP, CBC, plasma biochemistry. In all dogs, plasma COP values were significantly lower (P=0.02) than whole blood COP, with a mean of difference of 0.5 mm Hg. The mean and median whole blood COP was 21.75 and 21.4 mm Hg, respectively, with a range of 17.9-27.1 mm Hg. The mean and median plasma COP was 21.2 and 20.9 mm Hg with a range of 16.7-28.9 mm Hg.
  
  
  CONCLUSIONS
  While significant difference exists between plasma and whole blood COP, the individual values are within expected reference intervals for dogs (21-25 mm Hg). Using either sample appears to provide the same information in clinically healthy dog; however, it is recommended that clinicians utilize the same sample type for comparison in an individual patient.
authors.affiliation: Department of Veterinary Medicine and Surgery, University of Missouri, Columbia, MO 65211, USA. adesolaodunayo@yahoo.com
authors.forename: Adesola
authors.initials: A
authors.lastname: Odunayo
authors.forename: Marie E
authors.initials: ME
authors.lastname: Kerl
mesh_terms: D000046:Academic Medical Centers; D000818:Animals; D001790:Blood Physiological Phenomena; D001798:Blood Proteins / Q000032:analysis*; D003102:Colloids / Q000032:analysis*; D004285:Dogs / Q000097:blood; D005260:Female; D008297:Male; D008923:Missouri; D009997:Osmotic Pressure / Q000502:physiology*; D010949:Plasma; D011446:Prospective Studies
chemical_list: D001798:Blood Proteins; D003102:Colloids