title: Drug-induced bullous pemphigoid: cases triggered by intravenous iodine and etanercept.
abstract: Bullous pemphigoid (BP) is one of the most common acquired immunobullous diseases. Rarely, the development of BP is attributed to drug exposure. We present two cases of BP, one triggered by intravenous iodine, and one associated with etanercept treatment in a patient with psoriasis; the first time, to our knowledge, that either of these associations has been reported. The recognition of occasional cases of drug-induced BP such as ours, with timely cessation of the offending agent, may produce rapid clinical improvement with decreased exposure to potent immunosuppressive therapy.
authors.affiliation: Department of Dermatology, Solihull Hospital, Heart of England NHS Foundation Trust, Lode Lane, Solihull, West Midlands, UK. justinek@doctors.org.uk
authors.forename: J
authors.initials: J
authors.lastname: Kluk
authors.forename: J M R
authors.initials: JM
authors.lastname: Goulding
authors.forename: J
authors.initials: J
authors.lastname: Bhat
authors.forename: T M
authors.initials: TM
authors.lastname: Finch
mesh_terms: D000891:Anti-Infective Agents, Local / Q000009:adverse effects*; D000068800:Etanercept; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000008:administration & dosage / Q000009:adverse effects*; D007166:Immunosuppressive Agents / Q000009:adverse effects*; D007275:Injections, Intravenous; D007455:Iodine / Q000008:administration & dosage / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D010391:Pemphigoid, Bullous / Q000139:chemically induced*; D011565:Psoriasis / Q000188:drug therapy; D018124:Receptors, Tumor Necrosis Factor / Q000008:administration & dosage
chemical_list: D000891:Anti-Infective Agents, Local; D007074:Immunoglobulin G; D007166:Immunosuppressive Agents; D018124:Receptors, Tumor Necrosis Factor; D007455:Iodine; D000068800:Etanercept