title: MR diffusion imaging in ischemic stroke.
abstract: Diffusion-weighted MRI provides image contrast that is dependent on the molecular motion of water. Diffusion-weighted imaging is the most reliable method for early detection of cerebral ischemia, for the definition of infarct core, and for the differentiation of acute ischemia from other disease processes that mimic stroke. Diffusion tensor imaging and diffusion kurtosis imaging may offer additional diagnostic information on the microstructural status of tissue. This review discusses the development and applications of diffusion-weighted imaging, diffusion tensor imaging, and diffusion kurtosis imaging in acute and chronic ischemia.
authors.affiliation: Neuroradiology Section, Department of Radiology, The Methodist Hospital, Weill Cornell Medical College, 6565 Fannin Street, Houston, TX 77030, USA. steve_fung@post.harvard.edu
authors.forename: Steve H
authors.initials: SH
authors.lastname: Fung
authors.forename: Luca
authors.initials: L
authors.lastname: Roccatagliata
authors.forename: R Gilberto
authors.initials: RG
authors.lastname: Gonzalez
authors.forename: Pamela W
authors.initials: PW
authors.lastname: Schaefer
mesh_terms: D002536:Cerebral Arteries / Q000473:pathology*; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods*; D006801:Humans; D002546:Ischemic Attack, Transient / Q000473:pathology*; D018810:Magnetic Resonance Angiography / Q000379:methods*; D020521:Stroke / Q000473:pathology*