title: Primary extraskeletal myxoid chondrosarcoma of the vulva.
abstract: Primary extraskeletal myxoid chondrosarcoma (EMC) of the vulva is extremely rare. There is little available information about the biological behavior and treatment strategy for primary EMC of the vulva. We report a rare case of primary EMC of the vulva treated surgically. A 24-year-old Japanese woman had demonstrated a small and elastic mass of the vulva and underwent enucleation of the mass at a previous hospital, but a definitive histopathological diagnosis was not obtained. Therefore, the patient was referred to our hospital for further evaluation and treatment. We histopathologically diagnosed the tumor as primary EMC of the vulva and performed vulvectomy with vulvoperineal reconstruction. Microscopic examination of the resected specimens demonstrated residual tumor nodules of EMC. However, there were no viable tumor cells at the surgical margin. Approximately two years after wide local excision was performed, the patient is doing well and there is no apparent recurrence of EMC.
authors.affiliation: Department of Obstetrics and Gynecology, Kyoto Prefectural University of Medicine, Japan. mosawada@koto.kpu-m.ac.jp
authors.forename: Morio
authors.initials: M
authors.lastname: Sawada
authors.forename: Naobumi
authors.initials: N
authors.lastname: Tochigi
authors.forename: Yuko
authors.initials: Y
authors.lastname: Sasajima
authors.forename: Tadashi
authors.initials: T
authors.lastname: Hasegawa
authors.forename: Takahiro
authors.initials: T
authors.lastname: Kasamatsu
authors.forename: Jo
authors.initials: J
authors.lastname: Kitawaki
mesh_terms: D000328:Adult; D002813:Chondrosarcoma / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D019651:Plastic Surgery Procedures; D016896:Treatment Outcome; D014844:Vulva / Q000473:pathology* / Q000601:surgery; D014846:Vulvar Neoplasms / Q000473:pathology* / Q000601:surgery