title: Regulation of flagellum number by FliA and FlgM and role in biofilm formation by Rhodobacter sphaeroides.
abstract: The FlgM secretion checkpoint plays a crucial role in coordinating bacterial flagellar assembly. Here we identify a new role for FlgM and FliA as part of a complex regulatory network which controls flagellum number and is essential for efficient swimming and biofilm formation in the monotrichous bacterium Rhodobacter sphaeroides.
authors.affiliation: Oxford Centre for Integrative Systems Biology and Department of Biochemistry, University of Oxford, South Parks Road, Oxford, UK.
authors.forename: David A
authors.initials: DA
authors.lastname: Wilkinson
authors.forename: Sarah J
authors.initials: SJ
authors.lastname: Chacko
authors.forename: Catherine
authors.initials: C
authors.lastname: Vénien-Bryan
authors.forename: George H
authors.initials: GH
authors.lastname: Wadhams
authors.forename: Judith P
authors.initials: JP
authors.lastname: Armitage
mesh_terms: D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism*; D018441:Biofilms; D005407:Flagella / Q000235:genetics / Q000378:metabolism*; D015964:Gene Expression Regulation, Bacterial; D012242:Rhodobacter sphaeroides / Q000235:genetics / Q000502:physiology*; D012808:Sigma Factor / Q000235:genetics / Q000378:metabolism*
chemical_list: D001426:Bacterial Proteins; D012808:Sigma Factor