title: 9G DNAChip: microarray based on the multiple interactions of 9 consecutive guanines.
abstract: We introduce the phenomenon of molecular recognition to immobilize oligonucleotides on AMCA slides for the production of 9G DNAChips. Facile and efficient method for the immobilization of the oligonucleotides appended with consecutive nine guanine bases is described. The 9G DNAChips shows more than 90% hybridization efficiency at 25 °C in 30 min.
authors.affiliation: Biometrix Technology, Inc. 202 BioVenture Plaza, Chuncheon, 200-161, Korea.
authors.forename: Keum-Soo
authors.initials: KS
authors.lastname: Song
authors.forename: Satish Balasaheb
authors.initials: SB
authors.lastname: Nimse
authors.forename: Joonbae
authors.initials: J
authors.lastname: Kim
authors.forename: Junghoon
authors.initials: J
authors.lastname: Kim
authors.forename: Van-Thuan
authors.initials: VT
authors.lastname: Nguyen
authors.forename: Van-Thao
authors.initials: VT
authors.lastname: Ta
authors.forename: Taisun
authors.initials: T
authors.lastname: Kim
mesh_terms: D006147:Guanine / Q000737:chemistry*; D009693:Nucleic Acid Hybridization; D020411:Oligonucleotide Array Sequence Analysis / Q000379:methods*; D015345:Oligonucleotide Probes / Q000737:chemistry; D013696:Temperature
chemical_list: D015345:Oligonucleotide Probes; D006147:Guanine