title: Anti-inflammatory and antioxidant activity of Ficus carica Linn. leaves.
abstract: Ficus carica Linn. (Moraceae) is commonly known as edible fig. The leaves, roots, fruits and latex of the plant are medicinally used in different diseases. The leaves are claimed to be effective in various inflammatory conditions like painful or swollen piles, insect sting and bites. However, there has been no report on anti-inflammatory and antioxidant activity of F. carica leaves. Therefore the aim of this study was to evaluate the anti-inflammatory and antioxidant activity of F. carica leaves. Our study validated the traditional claim with pharmacological data. Anti-inflammatory and antioxidant activity of the drug could be due to the presence of steroids and flavanoids, respectively, which are reported to be present in the drug. Furthermore, the anti-inflammatory activity of the drug could be due to its free radical scavenging activity. Further work is also required to isolate and characterise the active constituents responsible for the anti-inflammatory activities.
authors.affiliation: Department of Pharmacognosy and Phytochemistry, Faculty of Pharmacy, Jamia Hamdard, New Delhi, India. babarasifpharma@gmail.com
authors.forename: B
authors.initials: B
authors.lastname: Ali
authors.forename: M
authors.initials: M
authors.lastname: Mujeeb
authors.forename: V
authors.initials: V
authors.lastname: Aeri
authors.forename: S R
authors.initials: SR
authors.lastname: Mir
authors.forename: M
authors.initials: M
authors.lastname: Faiyazuddin
authors.forename: F
authors.initials: F
authors.lastname: Shakeel
mesh_terms: D000818:Animals; D000893:Anti-Inflammatory Agents / Q000737:chemistry* / Q000627:therapeutic use*; D000975:Antioxidants / Q000737:chemistry* / Q000627:therapeutic use*; D004487:Edema / Q000188:drug therapy / Q000276:immunology; D030681:Ficus / Q000737:chemistry*; D007213:Indomethacin / Q000627:therapeutic use; D018515:Plant Leaves / Q000737:chemistry*; D051381:Rats; D017208:Rats, Wistar
chemical_list: D000893:Anti-Inflammatory Agents; D000975:Antioxidants; D007213:Indomethacin