title: New steroidal lactones and homomonoterpenic glucoside from fruits of Malva sylvestris L.
abstract: Phytochemical investigation of the ethanolic extract of defatted fruits of Malva sylvestris Linn. (Malvaceae) led to the isolation of six new steroidal lactones and a homomonoterpenic glucoside along with beta-sitosterol-3-beta-D-glucopyranoside. The structures of new phytoconstituents have been elucidated as cholest-5-en-3a-ol-18(21)-olide (sylvestrosterol A), cholest-9(11)-en-3alpha-ol-18(21)-olide (sylvestrosterol B), cholest-4,6,22-trien-3alpha-ol-18(21)-olide (sylvestrosterol C), 2-methyl-6-methylene-n-decan-2-olyl- 3beta-D-glucopyranoside (malvanoyl glucoside), cholest-7-en-18(21)-olide-3alpha-olyl-3beta-D-glucopyranoside (sylvestrogenin A), cholest-9(11)-en-18(21)-olide-3alpha-olyl-3beta-D-glucopyranoside (sylvestrogenin B) and cholest-5-en-8(21)-olide-3alpha-olyl-3beta-D-glucopyranoside (sylvestrogenin C).The structures of all these phytoconstituents have been established on the basis of spectral data analysis and chemical reactions.
authors.affiliation: Drug Standardization Research Unit, Department of Chemistry, Faculty of Science, Jamia Hamdard, Hamdard Nagar, New Delhi-110062, India.
authors.forename: Akhlaq
authors.initials: A
authors.lastname: Mustafa
authors.forename: Mohammed
authors.initials: M
authors.lastname: Ali
mesh_terms: D002845:Chromatography; D005638:Fruit; D005960:Glucosides / Q000737:chemistry / Q000302:isolation & purification*; D007783:Lactones / Q000737:chemistry / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D028501:Malva / Q000737:chemistry*; D015394:Molecular Structure; D039821:Monoterpenes / Q000737:chemistry / Q000302:isolation & purification*; D012855:Sitosterols / Q000302:isolation & purification; D021241:Spectrometry, Mass, Electrospray Ionization; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet
chemical_list: D005960:Glucosides; D007783:Lactones; D039821:Monoterpenes; D012855:Sitosterols; C472604:sitosterol-3-O-glucopyranoside