title: Copper-catalyzed direct thiolation of azoles with aliphatic thiols.
abstract: Cu(II)-catalyzed direct thiolation of azoles with thiols is described via intermolecular C-S bond formation/C-H functionalization under oxidative conditions. Both aryl thiols and aliphatic thiols are used as coupling partners, and furnished the thiolation products in moderate to good yields. The reaction is compatible with a wide range of heterocycles including oxazole, thiazole, imidazole and oxadiazole.
authors.affiliation: State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, People's Republic of China.
authors.forename: An-Xi
authors.initials: AX
authors.lastname: Zhou
authors.forename: Xue-Yuan
authors.initials: XY
authors.lastname: Liu
authors.forename: Ke
authors.initials: K
authors.lastname: Yang
authors.forename: Shu-Chun
authors.initials: SC
authors.lastname: Zhao
authors.forename: Yong-Min
authors.initials: YM
authors.lastname: Liang
mesh_terms: D001393:Azoles / Q000737:chemistry*; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D005227:Fatty Acids / Q000737:chemistry; D010084:Oxidation-Reduction; D013438:Sulfhydryl Compounds / Q000737:chemistry*
chemical_list: D001393:Azoles; D005227:Fatty Acids; D013438:Sulfhydryl Compounds; D003300:Copper