title: [Outcomes of combined mitral valve repair surgery and aortic valve replacement in IKEM Praha].
abstract: OBJECTIVE
  We retrospectively analyzed long-term outcome of concomitant mitral valve repair and aortic valve replacement.
  
  
  METHODS
  From 1996 to 2009 we performed mitral valve plasty with aortic valve replacement in 50 patients. Clinical and echocardiographic data were obtained from computer database and hospital records. Missing data were obtained through mailed questionnaire. We evaluated hospital mortality, long-term survival, thromboembolic and hemorrhagic complications and TR of 3+ on follow up echocardiography.
  
  
  RESULTS
  Four patients who had previously undergone aortic valve surgery were excluded from the study. Aortic valve pathology was stenosis in 21 patients, regurgitation in 20 and 4 patients presented with mixed aortic disease. The etiology of mitral regurgitation was rheumatic in 6, non-rheumatic in 31 and infective in 6 patients. Aortic valve was replaced with mechanical prosthesis in 22 (mean age 59) and tissue prosthesis in 24 (mean age 71) patients. Additional surgical procedure was performed in 26 patients. Follow-up was 94% complete, with a mean duration of 51 months. Hospital mortality was 13%. Two and five year survival was 79% and 64% respectively. We noted one case of retroperitoneal hemorrhage and one stroke. We recorded 9 (19.6%) patients with residual TR of more than 3+ grade on follow up echocardiography. Out of 9 patients with residual TR, 3 were operated for rheumatic and 6 for non-rheumatic mitral valve disease. One patients underwent successful mitral valve replacement with mechanical prosthesis, 3 died and 5 are treated expectantly.
  
  
  CONCLUSIONS
  We conclude that concomitant mitral valve repair with aortic valve replacement has high hospital mortality, excellent long-term survival and low complication rate. The durability of mitral valve repair in patients with rheumatic mitral valve disease is limited and replacement, rather that repair should be considered in this patient group.
authors.affiliation: Klinika Kardiovaskulární chirurgie IKEM Praha. maub@ikem.cz
authors.forename: M
authors.initials: M
authors.lastname: Urban
authors.forename: J
authors.initials: J
authors.lastname: Pirk
authors.forename: I
authors.initials: I
authors.lastname: Skalský
authors.forename: O
authors.initials: O
authors.lastname: Szárszoi
authors.forename: I
authors.initials: I
authors.lastname: Netuka
mesh_terms: D000368:Aged; D001021:Aortic Valve / Q000601:surgery*; D001705:Bioprosthesis; D004696:Endocarditis / Q000601:surgery; D005260:Female; D019918:Heart Valve Prosthesis Implantation; D006801:Humans; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve / Q000601:surgery*; D008944:Mitral Valve Insufficiency / Q000601:surgery; D012214:Rheumatic Heart Disease / Q000601:surgery