title: Gold-catalyzed regioselective oxidation of terminal allenes: formation of α-methanesulfonyloxy methyl ketones.
abstract: Synthetically useful α-methanesulfonyloxy methyl ketones are readily prepared in one-step from terminal allenes in fair to good yields. The chemistry relies on a gold-catalyzed intermolecular oxidation of the 1,2-diene unit using 3,5-dichloropyridine N-oxide as the oxidant. The reaction tolerates a range of functional groups and shows excellent regioselectivity.
authors.affiliation: Department of Chemistry and Biochemistry, University of California, Santa Barbara, California, 93106, USA.
authors.forename: Yingdong
authors.initials: Y
authors.lastname: Luo
authors.forename: Guozhu
authors.initials: G
authors.lastname: Zhang
authors.forename: Erik S
authors.initials: ES
authors.lastname: Hwang
authors.forename: Thomas A
authors.initials: TA
authors.lastname: Wilcoxon
authors.forename: Liming
authors.initials: L
authors.lastname: Zhang