title: Symmetry in number of retrieved oocytes between two ovaries: a possible predictor of in vitro fertilization outcome.
abstract: OBJECTIVE
  To examine the relationship between the ratio of difference in number of retrieved oocytes from the two ovaries to total number of oocytes (difference ratio, |N(RO) - N(LO)|/N(TOTAL)) and in?vitro fertilization (IVF) outcome.
  
  
  METHODS
  Retrospective review of medical record for infertility patients with intact two ovaries who had undertaken controlled ovarian stimulation (COS) and IVF cycles in Seoul National University Hospital was conducted. Characteristics and IVF outcomes were compared according to the difference ratio (|N(RO) - N(LO)|/N(TOTAL)) using student t-test and χ² test. To adjust for the effect of confounding factors, binary logistic regression test was performed.
  
  
  RESULTS
  When the study population was divided according to the difference ratio by cut-off value of 0.4, patients with difference ratio less than 0.4 showed significantly higher pregnancy rate (25.7% vs. 17.1%, p = 0.021). A significant correlation was noted between the difference ratio and achievement of pregnancy after adjustment for patient's age and total number of top quality embryos transferred (adjusted OR = 0.40, 95% CI 0.19-0.83, p = 0.014).
  
  
  CONCLUSIONS
  The difference ratio of retrieved oocytes in patients with intact two ovaries was observed to have prognostic value in IVF cycles.
authors.affiliation: Department of Obstetrics and Gynecology, Seoul National University College of Medicine.
authors.forename: Seung Ah
authors.initials: SA
authors.lastname: Choe
authors.forename: Seung-Yup
authors.initials: SY
authors.lastname: Ku
authors.forename: Byung Chul
authors.initials: BC
authors.lastname: Jee
authors.forename: Chang Suk
authors.initials: CS
authors.lastname: Suh
authors.forename: Seok Hyun
authors.initials: SH
authors.lastname: Kim
authors.forename: Young Min
authors.initials: YM
authors.lastname: Choi
authors.forename: Jung
authors.initials: J
authors.lastname: Gu Kim
authors.forename: Shin
authors.initials: S
authors.lastname: Yong Moon
mesh_terms: D000328:Adult; D002452:Cell Count; D004624:Embryo Transfer / Q000706:statistics & numerical data; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D007246:Infertility / Q000175:diagnosis* / Q000453:epidemiology / Q000628:therapy*; D008297:Male; D054315:Oocyte Retrieval / Q000379:methods / Q000706:statistics & numerical data*; D009865:Oocytes / Q000166:cytology / Q000473:pathology / Q000502:physiology; D010053:Ovary / Q000166:cytology* / Q000473:pathology / Q000502:physiology; D010062:Ovulation Induction / Q000379:methods / Q000706:statistics & numerical data; D011247:Pregnancy; D011256:Pregnancy Outcome; D011379:Prognosis; D012189:Retrospective Studies; D016896:Treatment Outcome