title: Determining optimum conditions for lipase-catalyzed synthesis of triethanolamine (TEA)-based esterquat cationic surfactant by a Taguchi robust design method.
abstract: A Taguchi robust design method with an L₉ orthogonal array was implemented to optimize experimental conditions for the biosynthesis of triethanolamine (TEA)-based esterquat cationic surfactants using an enzymatic reaction method. The esterification reaction conversion% was considered as the response. Enzyme amount, reaction time, reaction temperature and molar ratio of substrates, [oleic acid: triethanolamine (OA:TEA)] were chosen as main parameters. As a result of the Taguchi analysis in this study, the molar ratio of substrates was found to be the most influential parameter on the esterification reaction conversion%. The amount of enzyme in the reaction had also a significant effect on reaction conversion%.
authors.affiliation: Department of Chemistry, Faculty of Science, Universiti Putra Malaysia, 43400 Selangor, Malaysia.
authors.forename: Hamid Reza Fard
authors.initials: HR
authors.lastname: Masoumi
authors.forename: Anuar
authors.initials: A
authors.lastname: Kassim
authors.forename: Mahiran
authors.initials: M
authors.lastname: Basri
authors.forename: Dzulkifly Kuang
authors.initials: DK
authors.lastname: Abdullah
mesh_terms: D002384:Catalysis; D002412:Cations / Q000737:chemistry*; D002621:Chemistry / Q000379:methods*; D004983:Ethanolamines / Q000737:chemistry*; D008049:Lipase / Q000378:metabolism*; D015233:Models, Statistical; D019301:Oleic Acid / Q000737:chemistry; D015203:Reproducibility of Results; D013501:Surface-Active Agents / Q000138:chemical synthesis*
chemical_list: D002412:Cations; D004983:Ethanolamines; D013501:Surface-Active Agents; D019301:Oleic Acid; C009546:triethanolamine; D008049:Lipase