title: [A case of amyloidosis of the ureter caused by primary macroglobulinemia].
abstract: A 78-year-old woman was referred to our hospital with chief complaint of colicky right flank pain. Computed tomography (CT) demonstrated right hydronephrosis and a wall thickening in the right ureteropelvic junction. Right nephroureterectomy was performed under a clinical diagnosis of invasive ureteral cancer. Histological examination revealed immunoglobulin light chain (AL) amyloidosis of the ureter. Although amyloid deposition seemed to be localized to the ureter alone, bone marrow biopsy revealed primary macroglobulinemia. After 23 months, no signs or symptoms suggesting the progression of amyloidosis or macroglobulinemia have been pointed out. AL amyloidosis arising secondarily to plasma cell disorder is called immunocytic amyloidosis. In general, immunocytic amyloidosis accompanies deposition of the amyloid protein to various organs of the whole body, and causes multiple clinical symptoms related to amyloid deposition. Even though the clinical manifestation indicates the localized disease like the presented case, close examination of immunocytic amyloidosis is important.
authors.affiliation: The Department of Urology, Kyoto University Graduate School of Medicine, Japan.
authors.forename: Yu
authors.initials: Y
authors.lastname: Miyazaki
authors.forename: Tomomi
authors.initials: T
authors.lastname: Kamba
authors.forename: Yosuke
authors.initials: Y
authors.lastname: Shimizu
authors.forename: Takahiro
authors.initials: T
authors.lastname: Inoue
authors.forename: Kazutoshi
authors.initials: K
authors.lastname: Okubo
authors.forename: Jun
authors.initials: J
authors.lastname: Watanabe
authors.forename: Koji
authors.initials: K
authors.lastname: Yoshimura
authors.forename: Akihiro
authors.initials: A
authors.lastname: Kanematsu
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Nishiyama
authors.forename: Osamu
authors.initials: O
authors.lastname: Ogawa
mesh_terms: D000368:Aged; D000686:Amyloidosis / Q000209:etiology* / Q000473:pathology; D005260:Female; D006801:Humans; D014515:Ureteral Diseases / Q000209:etiology* / Q000473:pathology; D008258:Waldenstrom Macroglobulinemia / Q000150:complications*