title: [Dynamics of morphological structures of platelets in patients with ischemic heart disease in dependence on blood levels of fatty acids].
abstract: Levels of fatty acids in platelets of ischemic heart disease (IHD) patients (n = 39) has been compared with those in healthy subjects (n = 12). Increased content of arachidonic acid and thromboxane A2 in platelets of IHD patients forms thrombogenic picture of IHD. High level of fibrinogen and decrease in heparin and antithrombin III in IHD patients facilitates formation of blood clots. Morphological examination of platelets in IHD patients has demonstrated an increase of levels of discocytes and spherocytes as well as appearance of small and large platelet-erythrocyte aggregates promoting blood slot formation.
authors.forename: E I
authors.initials: EI
authors.lastname: Sokolov
authors.forename: L I
authors.initials: LI
authors.lastname: Buriachkovskaia
authors.forename: A A
authors.initials: AA
authors.lastname: Zykova
authors.forename: I V
authors.initials: IV
authors.lastname: Goloborodova
mesh_terms: D000991:Antithrombins / Q000378:metabolism; D016718:Arachidonic Acid / Q000378:metabolism*; D001779:Blood Coagulation Factors / Q000378:metabolism; D001792:Blood Platelets / Q000378:metabolism / Q000473:pathology; D004903:Erythrocyte Aggregation; D004907:Erythrocyte Deformability; D006801:Humans; D017202:Myocardial Ischemia / Q000209:etiology / Q000378:metabolism / Q000473:pathology / Q000503:physiopathology; D010973:Platelet Adhesiveness; D010974:Platelet Aggregation; D013927:Thrombosis / Q000150:complications / Q000378:metabolism / Q000473:pathology / Q000503:physiopathology; D013928:Thromboxane A2 / Q000378:metabolism*
chemical_list: D000991:Antithrombins; D001779:Blood Coagulation Factors; D016718:Arachidonic Acid; D013928:Thromboxane A2