title: Megaloblastic anemia--a rare cause.
abstract: A 2- year- old boy presented with non responsive megaloblastic anemia, growth failure and developmental delay. Blood levels of B(12), folic acid and iron were normal. Tandem mass spectroscopy for common inborn errors of metabolism did not reveal any abnormality. There was an increased excretion of orotic acid in urine. The authors report this as a rare cause of megaloblastic anemia.
authors.affiliation: Department of Pediatrics, University College of Medical Sciences and Guru Tegh Bahadur Hospital, New Delhi, India.
authors.forename: Sanjib Kr
authors.initials: SK
authors.lastname: Debnath
authors.forename: Anju
authors.initials: A
authors.lastname: Aggarwal
authors.forename: Hema
authors.initials: H
authors.lastname: Mittal
mesh_terms: D000749:Anemia, Megaloblastic / Q000209:etiology*; D002675:Child, Preschool; D006801:Humans; D008297:Male; D009962:Orotate Phosphoribosyltransferase / Q000172:deficiency; D009964:Orotidine-5'-Phosphate Decarboxylase / Q000172:deficiency; D011686:Purine-Pyrimidine Metabolism, Inborn Errors / Q000175:diagnosis*
chemical_list: D009962:Orotate Phosphoribosyltransferase; D009964:Orotidine-5'-Phosphate Decarboxylase