title: Dynamic and structural formation of a thrombus: the inciting event of arterial ischemic stroke.
abstract: Arterial ischemic stroke occurs as a result of abnormal clinical circumstances that alter hemostasis and cause thrombosis, either within a vessel or as an embolic event. Understanding normal hemostasis, including differences between children (developmental hemostasis) and adults, will provide background for determining the pathophysiology of stroke and potential treatments.
authors.affiliation: University of Alberta, Stollery Children's Hospital, Edmonton, Alberta, Canada. Patti.massicotte@albertahealthservices.ca
authors.forename: M Patricia
authors.initials: MP
authors.lastname: Massicotte
authors.forename: M E
authors.initials: ME
authors.lastname: Bauman
mesh_terms: D000818:Animals; D001158:Arteries / Q000503:physiopathology*; D006487:Hemostasis; D006801:Humans; D007511:Ischemia / Q000150:complications*; D008954:Models, Biological; D017711:Nonlinear Dynamics; D020521:Stroke / Q000209:etiology*; D013927:Thrombosis / Q000209:etiology*