title: The GUDMAP database--an online resource for genitourinary research.
abstract: The GenitoUrinary Development Molecular Anatomy Project (GUDMAP) is an international consortium working to generate gene expression data and transgenic mice. GUDMAP includes data from large-scale in situ hybridisation screens (wholemount and section) and microarray gene expression data of microdissected, laser-captured and FACS-sorted components of the developing mouse genitourinary (GU) system. These expression data are annotated using a high-resolution anatomy ontology specific to the developing murine GU system. GUDMAP data are freely accessible at www.gudmap.org via easy-to-use interfaces. This curated, high-resolution dataset serves as a powerful resource for biologists, clinicians and bioinformaticians interested in the developing urogenital system. This paper gives examples of how the data have been used to address problems in developmental biology and provides a primer for those wishing to use the database in their own research.
authors.affiliation: MRC Human Genetics Unit, Western General Hospital, Edinburgh EH4 2XU, UK. sharding@hgu.mrc.ac.uk
authors.forename: Simon D
authors.initials: SD
authors.lastname: Harding
authors.forename: Chris
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authors.lastname: Armit
authors.forename: Jane
authors.initials: J
authors.lastname: Armstrong
authors.forename: Jane
authors.initials: J
authors.lastname: Brennan
authors.forename: Ying
authors.initials: Y
authors.lastname: Cheng
authors.forename: Bernard
authors.initials: B
authors.lastname: Haggarty
authors.forename: Derek
authors.initials: D
authors.lastname: Houghton
authors.forename: Sue
authors.initials: S
authors.lastname: Lloyd-MacGilp
authors.forename: Xingjun
authors.initials: X
authors.lastname: Pi
authors.forename: Yogmatee
authors.initials: Y
authors.lastname: Roochun
authors.forename: Mehran
authors.initials: M
authors.lastname: Sharghi
authors.forename: Christopher
authors.initials: C
authors.lastname: Tindal
authors.forename: Andrew P
authors.initials: AP
authors.lastname: McMahon
authors.forename: Brian
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authors.lastname: Gottesman
authors.forename: Melissa H
authors.initials: MH
authors.lastname: Little
authors.forename: Kylie
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authors.lastname: Georgas
authors.forename: Bruce J
authors.initials: BJ
authors.lastname: Aronow
authors.forename: S Steven
authors.initials: SS
authors.lastname: Potter
authors.forename: Eric W
authors.initials: EW
authors.lastname: Brunskill
authors.forename: E Michelle
authors.initials: EM
authors.lastname: Southard-Smith
authors.forename: Cathy
authors.initials: C
authors.lastname: Mendelsohn
authors.forename: Richard A
authors.initials: RA
authors.lastname: Baldock
authors.forename: Jamie A
authors.initials: JA
authors.lastname: Davies
authors.forename: Duncan
authors.initials: D
authors.lastname: Davidson
mesh_terms: D000818:Animals; D030541:Databases, Genetic; D006801:Humans; D020407:Internet; D051379:Mice; D012984:Software; D014566:Urogenital System / Q000254:growth & development / Q000378:metabolism*