title: [Statins can maybe reduce the risk of venous thromboembolism].
abstract: Recent reports suggest beneficial effects of statin treatment on risk of venous thromboembolism (VTE). This review studies the existing literature on statins and VTE: one meta-analysis, one randomized controlled trial, four cohort studies and eight case-control studies. The hypothesis of a risk reducing effect of statins on recurrent VTE is supported, but the included studies are heterogeneous; and there is a risk of uncontrolled confounding. Randomized clinical trials aimed at clarifying whether statins can prevent recurrent VTE or not are warranted.
authors.affiliation: Kardiologisk Afdeling, Aarhus Universitetshospital, Aalborg Sygehus, 9100 Aalborg, Denmark.
authors.forename: Anne Pernille
authors.initials: AP
authors.lastname: Toft-Petersen
authors.forename: Reimar Wernich
authors.initials: RW
authors.lastname: Thomsen
authors.forename: Erik Berg
authors.initials: EB
authors.lastname: Schmidt
authors.forename: Torben Bjerregaard
authors.initials: TB
authors.lastname: Larsen
mesh_terms: D000924:Anticholesteremic Agents / Q000627:therapeutic use*; D019317:Evidence-Based Medicine; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000627:therapeutic use*; D016032:Randomized Controlled Trials as Topic; D012008:Recurrence; D054556:Venous Thromboembolism / Q000517:prevention & control*
chemical_list: D000924:Anticholesteremic Agents; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors