title: Iron-promoted C-C bond cleavage of 1,3-diketones: a route to 1,2-diketones under mild reaction conditions.
abstract: A conceptual method for the preparation of 1,2-diketones is reported. The selective C-C bond cleavage of 1,3-diketones affords the 1,2-diketones in high yields under mild reaction conditions in air by the use of FeCl(3) as the catalyst and tert-butyl nitrite (TBN) as the oxidant without the use of solvent. The possible reaction mechanism is discussed. This protocol provides an expeditious route to the useful 1,2-diketones.
authors.affiliation: Department of Chemistry, Zhejiang University, Hangzhou, China.
authors.forename: Lehao
authors.initials: L
authors.lastname: Huang
authors.forename: Kai
authors.initials: K
authors.lastname: Cheng
authors.forename: Bangben
authors.initials: B
authors.lastname: Yao
authors.forename: Yongju
authors.initials: Y
authors.lastname: Xie
authors.forename: Yuhong
authors.initials: Y
authors.lastname: Zhang
mesh_terms: D002384:Catalysis; D002712:Chlorides / Q000737:chemistry*; D005290:Ferric Compounds / Q000737:chemistry*; D007659:Ketones / Q000138:chemical synthesis* / Q000737:chemistry*; D015394:Molecular Structure; D010084:Oxidation-Reduction; D013237:Stereoisomerism
chemical_list: D002712:Chlorides; D005290:Ferric Compounds; D007659:Ketones; C024555:ferric chloride