title: Coagulation dynamics of a blood sample by multiple scattering analysis.
abstract: We report a new technique to measure coagulation dynamics on whole-blood samples. The method relies on the analysis of the speckle figure resulting from a whole-blood sample mixed with coagulation reagent and introduced in a thin chamber illuminated with a coherent light. A dynamic study of the speckle reveals a typical behavior due to coagulation. We compare our measured coagulation times to a reference method obtained in a medical laboratory.
authors.affiliation: DTBS/SBSC/LCIV, CEA/Leti, 17 rue des Martyrs, Grenoble Cedex 9, France.
authors.forename: Magalie
authors.initials: M
authors.lastname: Faivre
authors.forename: Philippe
authors.initials: P
authors.lastname: Peltié
authors.forename: Anne
authors.initials: A
authors.lastname: Planat-Chrétien
authors.forename: Marie-Line
authors.initials: ML
authors.lastname: Cosnier
authors.forename: Myriam
authors.initials: M
authors.lastname: Cubizolles
authors.forename: Christophe
authors.initials: C
authors.lastname: Nougier
authors.forename: Claude
authors.initials: C
authors.lastname: Négrier
authors.forename: Patrick
authors.initials: P
authors.lastname: Pouteau
mesh_terms: D001777:Blood Coagulation / Q000502:physiology*; D004867:Equipment Design; D019544:Equipment Failure Analysis; D006801:Humans; D007834:Lasers; D008027:Light; D010783:Photometry / Q000295:instrumentation*; D012031:Refractometry / Q000295:instrumentation*; D012542:Scattering, Radiation; D014914:Whole Blood Coagulation Time / Q000295:instrumentation*