title: Prophylactic antibiotics for variceal hemorrhage: clostridium difficile infection still can be a risk.
abstract: Bron et al presented a retrospective study regarding the prophylactic use of antibiotics for variceal hemorrhage. Antibiotics appeared to improve the survival rate of patients without increasing clostridium difficile infection (CDI). We argue against the conclusion of the authors and consider that this result may be simply due to concurrent use of metronidazole, a therapeutic agent against CDI.
authors.forename: Naohiro
authors.initials: N
authors.lastname: Okano
authors.forename: Kentaro
authors.initials: K
authors.lastname: Iwata
mesh_terms: D019072:Antibiotic Prophylaxis; D016360:Clostridioides difficile; D003015:Clostridium Infections / Q000517:prevention & control*; D004932:Esophageal and Gastric Varices; D006471:Gastrointestinal Hemorrhage / Q000188:drug therapy*; D006801:Humans; D012307:Risk Factors