title: Randomized controlled trial of full and brief cognitive-behaviour therapy and wait-list for paediatric obsessive-compulsive disorder.
abstract: BACKGROUND
  Reviews and practice guidelines for paediatric obsessive-compulsive disorder (OCD) recommend cognitive-behaviour therapy (CBT) as the psychological treatment of choice, but note that it has not been sufficiently evaluated for children and adolescents and that more randomized controlled trials are needed. The aim of this trial was to evaluate effectiveness and optimal delivery of CBT, emphasizing cognitive interventions.
  
  
  METHODS
  A total of 96 children and adolescents with OCD were randomly allocated to the three conditions each of approximately 12 weeks duration: full CBT (average therapist contact: 12 sessions) and brief CBT (average contact: 5 sessions, with use of therapist-guided workbooks), and wait-list/delayed treatment. The primary outcome measure was the child version of the semi-structured interviewer-based Yale-Brown Obsessive Compulsive Scale.
  
  
  BACKGROUND
  http://www.controlled-trials.com/ISRCTN/; unique identifier: ISRCTN29092580.
  
  
  RESULTS
  There was statistically significant symptomatic improvement in both treatment groups compared with the wait-list group, with no significant differences in outcomes between the two treatment groups. Controlled treatment effect sizes in intention-to-treat analyses were 2.2 for full CBT and 1.6 for brief CBT. Improvements were maintained at follow-up an average of 14 weeks later.
  
  
  CONCLUSIONS
  The findings demonstrate the benefits of CBT emphasizing cognitive interventions for children and adolescents with OCD and suggest that relatively lower therapist intensity delivery with use of therapist-guided workbooks is an efficient mode of delivery.
authors.affiliation: Psychology Department, Institute of Psychiatry, Kings College London, London, UK. d.bolton@iop.kcl.ac.uk
authors.forename: Derek
authors.initials: D
authors.lastname: Bolton
authors.forename: Tim
authors.initials: T
authors.lastname: Williams
authors.forename: Sean
authors.initials: S
authors.lastname: Perrin
authors.forename: Linda
authors.initials: L
authors.lastname: Atkinson
authors.forename: Catherine
authors.initials: C
authors.lastname: Gallop
authors.forename: Polly
authors.initials: P
authors.lastname: Waite
authors.forename: Paul
authors.initials: P
authors.lastname: Salkovskis
mesh_terms: D000293:Adolescent; D002648:Child; D015928:Cognitive Behavioral Therapy / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D009771:Obsessive-Compulsive Disorder / Q000523:psychology* / Q000628:therapy*; D013997:Time Factors; D016896:Treatment Outcome; D014850:Waiting Lists