title: Pediatric obstructive fibrinous tracheal pseudomembrane--characteristics and management with flexible bronchoscopy.
abstract: OBJECTIVE
  To evaluate the incidence, characteristics, flexible bronchoscopy (FB) findings, interventions and outcome of pediatric obstructive fibrinous tracheal pseudomembrane (OFTP) in our pediatric and neonatal intensive care units (ICUs).
  
  
  METHODS
  This is a retrospective study of medical and FB video records in a single tertiary university-affiliated teaching hospital over a ten-year period. Data was collected from patients who were admitted and extubated of endotracheal tube in the ICUs with a FB diagnosis of an OFTP-like lesion. The associated medical information, FB interventions and video records were reviewed and analyzed.
  
  
  RESULTS
  Eight patients with OFTP were enrolled, with an incidence rate of 1.48% in the postextubation respiratory distress patients. Mean age was 32 ± 32 months (range, 2 months to 13 years); mean body weight was 13.7 ± 8.1 kg (range, 4.3-45 kg); mean intubation period was 37.6 ± 12.3h; mean time for symptoms to develop after extubation was 3.6 ± 1.4h. Symptoms lasted for 20.8 ± 20.3h before FB examination. All patients were accurately diagnosed with OFTP at the first postextubation FB examination and revealed various morphologies. The estimated cross-sectional tracheal lumen was reduced by 70-90% and the mean length of lesion was 18.1 ± 5.2mm (range, 10-30 mm). All OFTP were successfully ablated immediately after the diagnosis in one FB session by using various techniques and without any complication. Total duration for both diagnostic and interventional FB was 19.4 ± 2.5 min. No recurrence was noted thereafter.
  
  
  CONCLUSIONS
  OFTP should always be considered in the event of postextubation respiratory distress, especially in the pediatric and neonatal ICUs. Early diagnosis and effective ablation can be achieved with aid of FB.
authors.affiliation: Department of Pediatrics, Taipei Veterans General Hospital, Institute of Emergency and Critical Care Medicine, School of Medicine, National Yang-Ming University, Taiwan. wjsoong@vghtpe.gov.tw
authors.forename: Wen-Jue
authors.initials: WJ
authors.lastname: Soong
authors.forename: Mei-Jy
authors.initials: MJ
authors.lastname: Jeng
authors.forename: Yu-Sheng
authors.initials: YS
authors.lastname: Lee
authors.forename: Pei-Chen
authors.initials: PC
authors.lastname: Tsao
authors.forename: Chia-Feng
authors.initials: CF
authors.lastname: Yang
authors.forename: Yen-Hui
authors.initials: YH
authors.lastname: Soong
mesh_terms: D000293:Adolescent; D000367:Age Factors; D000402:Airway Obstruction / Q000175:diagnosis* / Q000453:epidemiology / Q000601:surgery; D020680:Bronchoscopes; D001999:Bronchoscopy / Q000379:methods; D015984:Causality; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D015897:Comorbidity; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D007363:Intensive Care Units, Neonatal; D015278:Intensive Care Units, Pediatric; D007442:Intubation, Intratracheal / Q000295:instrumentation / Q000379:methods; D008297:Male; D012131:Respiratory Insufficiency / Q000175:diagnosis / Q000453:epidemiology / Q000601:surgery; D012189:Retrospective Studies; D012307:Risk Factors; D012737:Sex Factors; D014132:Trachea / Q000473:pathology*; D014135:Tracheal Stenosis / Q000175:diagnosis* / Q000453:epidemiology / Q000601:surgery; D016896:Treatment Outcome