title: [Antithrombotic therapy in the secondary prevention of stroke].
abstract: The review is devoted to the secondary prevention of ischemic events after ischemic stroke. Recommendations for antithrombotic therapy and prolonged indirect anticoagulant therapy with INR monitoring based on evidence-based medicine of the secondary prevention of ischemic stroke and TIA are presented. Patients who do not need anticoagulants should receive antiplatelet therapy. Due to the increasing number of patients resistant to antiaggregant therapy, the rapid and adequate evaluation of platelet function is needed. Current laboratory diagnostic methods have some shortcomings and do not meet criteria of evidence-based medicine. It is necessary to improve the laboratory diagnosis with the elaboration of reliable standardized methods.
authors.forename: E V
authors.initials: EV
authors.lastname: Mel'nikova
authors.forename: M I
authors.initials: MI
authors.lastname: Kadinskaia
authors.forename: D V
authors.initials: DV
authors.lastname: Gerasimenko
authors.forename: A A
authors.initials: AA
authors.lastname: Shmonin
mesh_terms: D000925:Anticoagulants / Q000627:therapeutic use*; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D006801:Humans; D002546:Ischemic Attack, Transient / Q000517:prevention & control*; D055502:Secondary Prevention; D020521:Stroke / Q000517:prevention & control*
chemical_list: D000925:Anticoagulants; D005343:Fibrinolytic Agents