title: Differential features between primary ankylosing spondylitis and spondylitis associated with psoriasis and inflammatory bowel disease.
abstract: OBJECTIVE
  To describe differential characteristics of axial involvement in ankylosing spondylitis (AS) as compared with that seen in psoriatic arthritis (PsA) and inflammatory bowel disease (IBD) in a cohort of Ibero-American patients.
  
  
  METHODS
  This study included 2044 consecutive patients with spondyloarthritis (SpA; ESSG criteria). Demographic, clinical, disease activity, functional ability, quality of life, work status, radiologic, and therapeutic data were evaluated and collected by RESPONDIA members from different Ibero-American countries between June and December 2006. Patients selected for analysis met modified New York criteria (mNY) for AS.
  
  
  RESULTS
  A total of 1264 patients met the New York criteria for AS: 1072 had primary AS, 147 had psoriatic, and 45 had IBD-associated spondylitis. Median disease duration was comparable among the 3 patient groups. Patients with primary AS were significantly younger (p = 0.01) and presented a higher frequency of males (p = 0.01) than the other 2 groups. Axial manifestations such as inflammatory back pain and sacroiliac pain were significantly more frequent in patients with primary AS (p = 0.05) versus other groups, whereas frequency of dactylitis, enthesitis, and peripheral arthritis was more common in patients with psoriatic spondylitis (p = 0.05). Spinal mobility was significantly more limited in patients with primary AS versus the other 2 groups (p = 0.0001). Radiologic changes according to BASRI total score were equally significant in primary AS. Disease activity (BASDAI), functional ability (BASFI), and quality of life (ASQoL) scores were comparable in the 3 groups.
  
  
  CONCLUSIONS
  Patients with primary AS had more severe axial involvement than those with spondylitis associated with psoriasis or IBD. Functional capacity, disease activity, and quality of life were comparable among the groups studied.
authors.affiliation: Section of Rheumatology, Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina.
authors.forename: Rodolfo
authors.initials: R
authors.lastname: Pérez Alamino
authors.forename: José A
authors.initials: JA
authors.lastname: Maldonado Cocco
authors.forename: Gustavo
authors.initials: G
authors.lastname: Citera
authors.forename: Pablo
authors.initials: P
authors.lastname: Arturi
authors.forename: Janitzia
authors.initials: J
authors.lastname: Vazquez-Mellado
authors.forename: Percival D
authors.initials: PD
authors.lastname: Sampaio-Barros
authors.forename: Diana
authors.initials: D
authors.lastname: Flores
authors.forename: Rubén
authors.initials: R
authors.lastname: Burgos-Vargas
authors.forename: Helena
authors.initials: H
authors.lastname: Santos
authors.forename: José E
authors.initials: JE
authors.lastname: Chavez-Corrales
authors.forename: Daniel
authors.initials: D
authors.lastname: Palleiro
authors.forename: Miguel A
authors.initials: MA
authors.lastname: Gutierrez
authors.forename: Elsa
authors.initials: E
authors.lastname: Vieira-Sousa
authors.forename: Fernando M
authors.initials: FM
authors.lastname: Pimentel-Santos
authors.forename: Sergio
authors.initials: S
authors.lastname: Paira
authors.forename: Alberto
authors.initials: A
authors.lastname: Berman
authors.forename: Mario
authors.initials: M
authors.lastname: Moreno-Alvarez
authors.forename: Eduardo
authors.initials: E
authors.lastname: Collantes-Estevez
mesh_terms: D000328:Adult; D015535:Arthritis, Psoriatic / Q000150:complications* / Q000473:pathology / Q000503:physiopathology*; D003430:Cross-Sectional Studies; D016208:Databases, Factual; D005260:Female; D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000150:complications* / Q000473:pathology / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D011788:Quality of Life; D025241:Spondylarthritis / Q000209:etiology* / Q000473:pathology / Q000503:physiopathology*; D013167:Spondylitis, Ankylosing / Q000473:pathology / Q000503:physiopathology*; D011795:Surveys and Questionnaires