title: Unknown: Yellow plaques on the chest and arms present for more than 6 years in an 80-year-old male. Diffuse normolipemic plane xanthomas presenting in association with myelodysplastic syndrome.
abstract: Yellow plaques and papules on the skin are hallmarks of xanthomas. These are not always associated with abnormalities in lipid profiles or their associated proteins. In cases of diffuse normolipemic plane xanthomas these cutaneous findings are often associated with myelodyscrasias including monoclonal gammopathy of unknown significance and multiple myeloma. Such clinical presentations may indicate that an evaluation for myelodyscrasias is warranted.
authors.affiliation: Department of Dermatology, University ot Texas Health Sciences Center Houston, Houston, TX, USA. ktmoxie@gmail.com
authors.forename: L Katie
authors.initials: LK
authors.lastname: Morrison
authors.forename: Isha E
authors.initials: IE
authors.lastname: Lopez
mesh_terms: D000369:Aged, 80 and over; D001536:Bence Jones Protein / Q000652:urine; D001853:Bone Marrow / Q000473:pathology; D006801:Humans; D007145:Immunoglobulin kappa-Chains / Q000032:analysis; D008055:Lipids / Q000032:analysis; D008297:Male; D009101:Multiple Myeloma / Q000150:complications* / Q000175:diagnosis / Q000652:urine; D009194:Myeloma Proteins / Q000032:analysis; D010257:Paraneoplastic Syndromes / Q000175:diagnosis* / Q000209:etiology / Q000378:metabolism / Q000473:pathology; D010950:Plasma Cells / Q000473:pathology; D013997:Time Factors; D014973:Xanthomatosis / Q000175:diagnosis* / Q000209:etiology / Q000378:metabolism / Q000473:pathology
chemical_list: D007145:Immunoglobulin kappa-Chains; D008055:Lipids; D009194:Myeloma Proteins; D001536:Bence Jones Protein