title: Novel application of α-azido aldehydes in multicomponent reactions: synthesis of triazolo-fused dihydrooxazinones via a Passerini reaction-dipolar cycloaddition strategy.
abstract: α-Azido aldehydes can be employed in Passerini reactions with isocyanides and various propiolic acids to afford the three-component adducts in moderate to good yields. These compounds undergo a straightforward azide-alkyne dipolar cycloaddition to furnish triazolo-fused dihydrooxazinones.
authors.affiliation: Università degli Studi di Genova, Dipartimento di Chimica e Chimica Industriale, Genova, Italy.
authors.forename: Fabio
authors.initials: F
authors.lastname: De Moliner
authors.forename: Stefano
authors.initials: S
authors.lastname: Crosignani
authors.forename: Andrea
authors.initials: A
authors.lastname: Galatini
authors.forename: Renata
authors.initials: R
authors.lastname: Riva
authors.forename: Andrea
authors.initials: A
authors.lastname: Basso
mesh_terms: D000447:Aldehydes / Q000737:chemistry*; D001386:Azides / Q000737:chemistry*; D060326:Chemistry Techniques, Synthetic; D003500:Cyclization; D015394:Molecular Structure; D010078:Oxazines / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism; D014230:Triazoles / Q000737:chemistry*
chemical_list: D000447:Aldehydes; D001386:Azides; D010078:Oxazines; D014230:Triazoles