title: Endoscopic stenting for post-transplant biliary stricture: usefulness of a novel removable covered metal stent.
abstract: BACKGROUND
  Endoscopic management of biliary anastomotic stricture (AS) following liver transplantation (LT) remains challenging. There are no dedicated self-expandable metal stents (SEMS) for this setting.
  
  
  METHODS
  A short fully covered SEMS (FCSEMS) with a retrieval suture was designed. Between July 2008 and June 2010, 13 patients with post-LT AS had this FCSEMS placed endoscopically, keeping the whole stent inside the bile duct across the AS with the retriever out of the papilla. The stents were removed by forceps under endoscopy according to a schedule. Technical success, complications, AS resolution and the outcome for the patients were observed.
  
  
  RESULTS
  Placement of the FCSEMS was successful on the first attempt in all patients. One patient with complicated infection did not respond to the stenting therapy and underwent stent retrieval ahead of schedule. Others kept well during stenting for a mean (SD) duration of 5.4 (1.7) months (range 2-8) without stent migration. All stents were removed successfully without great difficulty. AS resolution was obtained in all 12 patients, who were closely followed up for a mean (SD) time of 12.1 (8.0) months (range 1-26.5) after stent removal. Stricture recurrence occurred in one, who underwent a successful re-intervention with a second FCSEMS. Others remain free from symptoms and have normal liver function up to now.
  
  
  CONCLUSIONS
  Endoscopic treatment of post-LT AS using a removable FCSEMS is technically feasible, safe, and effective. This dedicated method may play an increasing role in the future management of benign biliary strictures.
authors.affiliation: Department of Endoscopy, Eastern Hepatobiliary Hospital, The Second Military Medical University, 225 Changhai Road, Shanghai 200438, China. drhubing@yahoo.cn
authors.forename: Bing
authors.initials: B
authors.lastname: Hu
authors.forename: Dao-Jian
authors.initials: DJ
authors.lastname: Gao
authors.forename: Feng-Hai
authors.initials: FH
authors.lastname: Yu
authors.forename: Tian-Tian
authors.initials: TT
authors.lastname: Wang
authors.forename: Ya-Min
authors.initials: YM
authors.lastname: Pan
authors.forename: Xiao-Ming
authors.initials: XM
authors.lastname: Yang
mesh_terms: D000328:Adult; D000368:Aged; D000714:Anastomosis, Surgical / Q000009:adverse effects; D002760:Cholangiopancreatography, Endoscopic Retrograde / Q000379:methods*; D002779:Cholestasis / Q000175:diagnosis / Q000209:etiology / Q000601:surgery*; D020099:Coated Materials, Biocompatible; D020878:Device Removal; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D016031:Liver Transplantation / Q000009:adverse effects* / Q000379:methods; D008297:Male; D008875:Middle Aged; D011474:Prosthesis Design; D012189:Retrospective Studies; D015607:Stents; D013536:Suture Techniques; D016896:Treatment Outcome
chemical_list: D020099:Coated Materials, Biocompatible