title: [Granular cell tumor of the esophagus: description of an infrequent benign tumor].
abstract: Granular cell tumors (GCT) are infrequent tumors first described by Abrikossoff in 1926. Gastrointestinal involvement occurs in about 6% of GCT, the esophagus being the most frequent location. These tumors are usually benign and asymptomatic and are usually found incidentally when an upper gastrointestinal endoscopy is carried out for another reason, showing an isolated polyp or sessile submucosal nodule, covered by intact yellowish mucosa and with firm consistency. Endoscopic ultrasonography has significantly improved the diagnosis of these lesions. Nowadays endoscopic mucosectomy is the treatment of choice of esophageal GCT with a low frequency of complications. Histologic analysis of the surgical specimen shows specific characteristics such as positivity for S-100 protein. We present two new cases of esophageal GCT that were diagnosed recently and discuss the most relevant features of this infrequent disease.
authors.affiliation: Sección de Aparato Digestivo, Hospital Universitario Infanta Leonor, Madrid, España. antoniodisan@yahoo.es
authors.forename: Antonio
authors.initials: A
authors.lastname: Díaz-Sánchez
authors.forename: Susana
authors.initials: S
authors.lastname: Soto
authors.forename: Angel
authors.initials: A
authors.lastname: Ponferrada
authors.forename: Rocío
authors.initials: R
authors.lastname: Campos
authors.forename: Mónica O
authors.initials: MO
authors.lastname: García
authors.forename: Dulce María
authors.initials: DM
authors.lastname: Benito
authors.forename: Jesús
authors.initials: J
authors.lastname: Troya
authors.forename: Beatriz
authors.initials: B
authors.lastname: Merino
authors.forename: Mercedes
authors.initials: M
authors.lastname: Aldeguer
mesh_terms: D000328:Adult; D000368:Aged; D014408:Biomarkers, Tumor; D004938:Esophageal Neoplasms / Q000737:chemistry / Q000150:complications / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000473:pathology* / Q000601:surgery; D005773:Gastroscopy; D016586:Granular Cell Tumor / Q000737:chemistry / Q000150:complications / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000473:pathology* / Q000601:surgery; D006356:Heartburn / Q000150:complications; D006801:Humans; D015994:Incidence; D008297:Male; D011472:Prostatitis / Q000150:complications; D009418:S100 Proteins / Q000032:analysis; D014463:Ultrasonography
chemical_list: D014408:Biomarkers, Tumor; D009418:S100 Proteins