title: A novel graphical representation of protein sequences and its application.
abstract: On the basis of information on the evolution of the 20 amino acids and their physiochemical characteristics, we propose a new two-dimensional (2D) graphical representation of protein sequences in this article. By this representation method, we use 2D data to represent three-dimensional information constructed by the amino acids' evolution index, the class information of amino acid based on physiochemical characteristics, and the order of the amino acids appearing in the protein sequences. Then, using discrete Fourier transform, the sequence signals with different lengths can be transformed to the frequency domain, in which the sequences are with the same length. A new method is used to analyze the protein sequence similarity and to predict the protein structural class. The experiments indicate that our method is effective and useful.
authors.affiliation: College of Information Science and Technology, Hunan University, Changsha, Hunan, China. jt_byliao@163.com
authors.forename: Bo
authors.initials: B
authors.lastname: Liao
authors.forename: Benyou
authors.initials: B
authors.lastname: Liao
authors.forename: Xinguo
authors.initials: X
authors.lastname: Lu
authors.forename: Zhi
authors.initials: Z
authors.lastname: Cao
mesh_terms: D000595:Amino Acid Sequence; D003196:Computer Graphics; D019143:Evolution, Molecular; D005583:Fourier Analysis; D008722:Methods; D011506:Proteins / Q000737:chemistry* / Q000145:classification / Q000235:genetics
chemical_list: D011506:Proteins