title: The effects of powdered fertilized eggs on depression.
abstract: This 12-week, double-blind, placebo-controlled study investigated the effects of fertilized egg powder (Young Tissue Extract; YT®) intake on outcome measures for depression. Fifty-five patients with depression were randomly assigned to receive YTE, YTE plus Melissa officinalis, or placebo for 12 weeks. At baseline, there were no significant differences in scores on the Hamilton Depression Rating Scale (HAM-D) or Beck Depression Inventory II (BDI-II) among the 3 groups. At 12 weeks, the HAM-D scores in groups treated with YTE or YTE with M. officinalis were both significantly lower than those in the placebo group. In addition, both treatment groups showed a significant improvement in depression as measured by the change in HAM-D scores from baseline to 12 weeks, whereas the placebo group showed no significant change. There were no significant differences between the 2 treatment groups. The study indicates that the fertilized egg powder has an antidepressive effect and may be an alternative or adjunct to antidepressive medication for some patients, but further research is necessary.
authors.affiliation: Department for Drug Abuse and Psychiatry, Blefjell Hospital, Kongsberg, Norway. est-skr@online.no
authors.forename: Ester
authors.initials: E
authors.lastname: Solberg
mesh_terms: D000328:Adult; D000368:Aged; D000818:Animals; D000928:Antidepressive Agents / Q000627:therapeutic use*; D002645:Chickens; D003863:Depression / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008297:Male; D031334:Melissa / Q000737:chemistry; D008875:Middle Aged; D010936:Plant Extracts / Q000627:therapeutic use; D011208:Powders; D014020:Tissue Extracts / Q000627:therapeutic use*; D016896:Treatment Outcome; D015053:Zygote / Q000737:chemistry*
chemical_list: D000928:Antidepressive Agents; D010936:Plant Extracts; D011208:Powders; D014020:Tissue Extracts