title: Intra-arterial thrombolysis and thrombectomy for acute ischemic stroke: technique and results.
abstract: Endovascular intraarterial (IA) strategies have emerged as important treatment options for patients with acute ischemic stroke who are ineligible for intravenous (IV) tissue plasminogen activator (tPA) or in whom such therapy has failed. The goal of this article is to provide a comprehensive review of percutaneous IA endovascular techniques aimed at revascularization in the setting of acute ischemic stroke from IA thrombolysis, mechanical thrombectomy, and primary intracranial stenting to retrievable-stent technology. For each modality, we focus on the existing clinical data, including our institutional experience and techniques.
authors.affiliation: Department of 1Neurosurgery, School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, NY, USA.
authors.forename: P T
authors.initials: PT
authors.lastname: Kan
authors.forename: D
authors.initials: D
authors.lastname: Orion
authors.forename: P
authors.initials: P
authors.lastname: Yashar
authors.forename: E I
authors.initials: EI
authors.lastname: Levy
mesh_terms: D000208:Acute Disease; D017130:Angioplasty / Q000379:methods*; D002545:Brain Ischemia / Q000000981:diagnostic imaging / Q000601:surgery* / Q000628:therapy; D006801:Humans; D007261:Infusions, Intra-Arterial; D011859:Radiography; D015607:Stents; D020521:Stroke / Q000000981:diagnostic imaging / Q000601:surgery* / Q000628:therapy; D017131:Thrombectomy / Q000379:methods*; D015912:Thrombolytic Therapy / Q000379:methods*