title: Treatment patterns and resource use among patients with comorbid diabetes mellitus and major depressive disorder.
abstract: OBJECTIVE
  To descriptively analyze patient characteristics, treatment patterns, and medical resource use of individuals with diabetes mellitus (DM) with and without comorbid major depressive disorder (MDD).
  
  
  METHODS
  Using an administrative claims database, commercially insured adults diagnosed with DM were studied over the calendar years 2005 and 2006. Demographic characteristics, comorbid illnesses, medication use, resource utilization, and costs were examined descriptively among patients with DM both with and without comorbid MDD.
  
  
  RESULTS
  Patients with DM and MDD were found to have a high resource burden, compared to patients with DM without MDD. Specifically, these patients were found to be more likely to be diagnosed with other comorbid medical conditions, to use multiple medications, and to use more healthcare services such as inpatient visits, emergency admissions, and outpatient visits. Consistent with these findings, costs for these patients were found to be $19,707 per year, compared to $11,237 for patients with DM without comorbid MDD.
  
  
  CONCLUSIONS
  The study utilizes data from an administrative claims database of insured individuals and hence, results may not be generalizable. Furthermore, the analysis is unable to examine clinical severity or indirect costs.
  
  
  CONCLUSIONS
  Compared to patients with DM and no comorbid MDD, patients with DM and MDD tend to have a larger burden of disease and to use more healthcare resources.
authors.affiliation: Eli Lilly and Company, Lilly Corporate Center, Indianapolis IN 46285, USA. LeTr@lilly.com
authors.forename: T Kim
authors.initials: TK
authors.lastname: Le
authors.forename: Brad
authors.initials: B
authors.lastname: Curtis
authors.forename: Kristin
authors.initials: K
authors.lastname: Kahle-Wrobleski
authors.forename: Joe
authors.initials: J
authors.lastname: Johnston
authors.forename: Diane
authors.initials: D
authors.lastname: Haldane
authors.forename: Cathy
authors.initials: C
authors.lastname: Melfi
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015897:Comorbidity; D003365:Costs and Cost Analysis; D003865:Major Depressive Disorder / Q000150:complications / Q000628:therapy*; D048909:Diabetes Complications / Q000628:therapy*; D003920:Diabetes Mellitus / Q000628:therapy*; D005260:Female; D006296:Health Services / Q000706:statistics & numerical data*; D006801:Humans; D007345:Insurance Claim Review / Q000706:statistics & numerical data; D008297:Male; D008875:Middle Aged; D055553:Prescription Drugs / Q000191:economics; D012959:Socioeconomic Factors; D055815:Young Adult
chemical_list: D055553:Prescription Drugs