title: Acute effects of Ginkgo biloba extract on vascular function and blood pressure.
abstract: We investigated whether a single dose of standardized Ginkgo biloba extract (GBE) can improve vascular function. A randomised controlled crossover trial was conducted on 14 young healthy men, who received GBE or placebo. The digital volume pulse was monitored to measure reflection index (DVP-RI) and stiffness index (DVP-SI) and peripheral augmentation index (pAIx) was assessed using radial pulse wave analysis at baseline and 2, 4 and 6 h after treatment. DVP-SI was slightly higher 2 h following GBE compared to placebo (P < 0.05); other outcome variables were unaffected by treatment.
authors.affiliation: Diabetes & Nutritional Sciences Division, School of Medicine, King's College London, London, UK.
authors.forename: Gillian
authors.initials: G
authors.lastname: Keheyan
authors.forename: Lauren A
authors.initials: LA
authors.lastname: Dunn
authors.forename: Wendy Louise
authors.initials: WL
authors.lastname: Hall
mesh_terms: D000293:Adolescent; D000328:Adult; D001794:Blood Pressure / Q000187:drug effects*; D002320:Cardiovascular Physiological Phenomena / Q000187:drug effects*; D018592:Cross-Over Studies; D020441:Ginkgo biloba; D006801:Humans; D008297:Male; D010936:Plant Extracts / Q000494:pharmacology*; D011674:Pulse; D016037:Single-Blind Method; D055815:Young Adult
chemical_list: D010936:Plant Extracts