title: Cutaneous granular cell tumor of the breast: a clinical diagnostic pitfall.
abstract: We report the clinical-morphological study of a granular cell tumor in dermal/hypodermal junction and subcutaneous fat left breast of an 83-year-old woman with a family history of breast carcinoma. Mammography study showed a spiculated lesion in the lower inner quadrant with suspicion of malignancy. The results of fine needle puncture-aspiration were inconclusive. Subsequent tumorectomy revealed a poorly-defined indurated lesion of 1.1 x 0.7 cm. The histopathology study showed a proliferation of cells with ample and granular cytoplasm that were positive for S100, CD 68 and inhibin and negative for hormonal receptors. We present a benign lesion that clinically reproduces a breast carcinoma.
  
  
  BACKGROUND
  Granular cell tumor; Breast; Differential diagnosis; Cutaneous.
authors.affiliation: Department of Pathology, University Hospital, Granada, Spain.
authors.forename: Jose
authors.initials: J
authors.lastname: Aneiros-Fernandez
authors.forename: Salvador
authors.initials: S
authors.lastname: Arias-Santiago
authors.forename: Husein
authors.initials: H
authors.lastname: Husein-Elahmed
authors.forename: Francisco
authors.initials: F
authors.lastname: Ovalle
authors.forename: Maria Ines Aroca
authors.initials: MI
authors.lastname: Siendones
authors.forename: Jose
authors.initials: J
authors.lastname: Aneiros-Cachaza