title: Metroplasty in a large population of women with septate uterus.
abstract: OBJECTIVE
  To determine the reproductive outcome after hysteroscopic metroplasty in women with septate uterus.
  
  
  METHODS
  Retrospective comparative single-center study (Canadian Task Force classification II-3).
  
  
  METHODS
  University-affiliated hospital.
  
  
  METHODS
  Two hundred forty-six patients with septate uterus undergoing hysteroscopic metroplasty between January 1998 and December 2007. The diagnosis was based on hysteroscopy and 3-dimensional ultrasonography. In the most cases laparoscopy was also available. The subjects were divided into 2 age-matched groups. Group 1 consisted of 108 women with unexplained infertility, and group 2 consisted of 138 women suffering from recurrent abortion.
  
  
  METHODS
  Patients underwent hysteroscopic metroplasty by use of resectoscopy with an equatorial semicircular loop cutting at 0 degree with monopolar energy. All septa were completely removed without complications of bleeding, infection, risk of perforation, visceral injury, or uterine dehiscence during pregnancy.
  
  
  RESULTS
  The 2 groups were compared in terms of reproductive performance in mean ± SD follow-up of 37 ± 18 months. In group 1, 61 (56.5%) patients achieved pregnancy. Seventy-one pregnancies ensued, including 1 twin gestation. Fourteen of the 71 pregnancies (19.7%) ended in miscarriage. In group 2, 90 (65.3%) patients achieved pregnancy. One hundred twenty-nine pregnancies ensued, including 2 twin gestations. Forty-four of the 129 pregnancies (34.1%) ended in miscarriage. The 2 groups have no significant differences in terms of reproductive outcome after surgery, except for the number of abortions, which was higher in group 2 (p <.05).
  
  
  CONCLUSIONS
  This study confirms that hysteroscopic metroplasty is a simple, safe, and rapid surgical procedure with no complications for achieving normal uterine architecture, which is peculiar to a good reproductive outcome. The use of an equatorial semicircular loop may give satisfactory and similar results to those obtained with Collin's loop.
authors.affiliation: Department of Obstetric, Gynecology and Reproductive Biology, S. Orsola Hospital, University Alma Mater Studiorum of Bologna, Bologna, Italy. roberto.paradisi@unibo.it
authors.forename: Roberto
authors.initials: R
authors.lastname: Paradisi
authors.forename: Rita
authors.initials: R
authors.lastname: Barzanti
authors.forename: Francesca
authors.initials: F
authors.lastname: Natali
authors.forename: Cesare
authors.initials: C
authors.lastname: Battaglia
authors.forename: Stefano
authors.initials: S
authors.lastname: Venturoli
mesh_terms: D000026:Abortion, Habitual / Q000209:etiology / Q000601:surgery; D000328:Adult; D004867:Equipment Design; D005260:Female; D006801:Humans; D015907:Hysteroscopy / Q000295:instrumentation; D007247:Infertility, Female / Q000209:etiology / Q000601:surgery; D012189:Retrospective Studies; D014599:Uterus / Q000002:abnormalities* / Q000601:surgery*