title: Uterine transplantation: one human case followed by a decade of experimental research in animal models.
abstract: Uterine transplantation (UTx) aims to treat unconditional uterine factor infertility by replacing a non-functioning or non-existing uterus. After one attempt of UTx in the human 10 years ago, intensive research has been performed. The results of these specific studies on surgical technique, ischaemia-reperfusion injury, immunosuppression and fertility are discussed.
authors.affiliation: Department of Obstetrics and Gynaecology, Griffith University, 16-30 High Street, Southport, Qld 4215, Australia. a.hanafy@griffith.edu.au
authors.forename: Ash
authors.initials: A
authors.lastname: Hanafy
authors.forename: César
authors.initials: C
authors.lastname: Diaz-Garcia
authors.forename: Michael
authors.initials: M
authors.lastname: Olausson
authors.forename: Mats
authors.initials: M
authors.lastname: Brännström
mesh_terms: D000818:Animals; D005260:Female; D006084:Graft Rejection / Q000276:immunology / Q000628:therapy; D013509:Gynecologic Surgical Procedures / Q000941:ethics / Q000379:methods; D006801:Humans; D007165:Immunosuppression Therapy; D007247:Infertility, Female / Q000601:surgery; D051379:Mice; D011247:Pregnancy; D011256:Pregnancy Outcome; D011817:Rabbits; D051381:Rats; D015427:Reperfusion Injury / Q000601:surgery; D012756:Sheep; D013552:Swine; D014599:Uterus / Q000637:transplantation*