title: An oppositional biogeography-based optimization technique to reconstruct organ boundaries in the human thorax using electrical impedance tomography.
abstract: Electrical impedance tomography (EIT) is a non-invasive imaging modality which has been actively studied for its industrial as well as medical applications. However, the performance of the inverse algorithms to reconstruct the conductivity images using EIT is often sub-optimal. Several factors contribute to this poor performance, including high sensitivity of EIT to the measurement noise, the rounding-off errors, the inherent ill-posed nature of the problem and the convergence to a local minimum instead of the global minimum. Moreover, the performance of many of these inverse algorithms heavily relies on the selection of initial guess as well as the accurate calculation of a gradient matrix. Considering these facts, the need for an efficient optimization algorithm to reach the correct solution cannot be overstated. This paper presents an oppositional biogeography-based optimization (OBBO) algorithm to estimate the shape, size and location of organ boundaries in a human thorax using 2D EIT. The organ boundaries are expressed as coefficients of truncated Fourier series, while the conductivities of the tissues inside the thorax region are assumed to be known a priori. The proposed method is tested with the use of a realistic chest-shaped mesh structure. The robustness of the algorithm has been verified, first through repetitive numerical simulations by adding randomly generated measurement noise to the simulated voltage data, and then with the help of an experimental setup resembling the human chest. An extensive statistical analysis of the estimated parameters using OBBO and its comparison with the traditional modified Newton-Raphson (mNR) method are presented. The results demonstrate that OBBO has significantly better estimation performance compared to mNR. Furthermore, it has been found that OBBO is robust to the initial guess of the size and location of the boundaries as well as offering a reasonable solution when the a priori knowledge of the conductivity of the organs is not very accurate.
authors.affiliation: Department of Electronic Engineering, Jeju National University, Jeju 690-756, Korea.
authors.forename: A
authors.initials: A
authors.lastname: Rashid
authors.forename: B S
authors.initials: BS
authors.lastname: Kim
authors.forename: A K
authors.initials: AK
authors.lastname: Khambampati
authors.forename: S
authors.initials: S
authors.lastname: Kim
authors.forename: K Y
authors.initials: KY
authors.lastname: Kim
mesh_terms: D000465:Algorithms; D017097:Electric Impedance; D005583:Fourier Analysis; D006321:Heart / Q000033:anatomy & histology; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D008168:Lung / Q000033:anatomy & histology; D008954:Models, Biological; D009929:Organ Size; D013909:Thorax / Q000033:anatomy & histology*; D014054:Tomography / Q000379:methods*