title: Mature cystic teratoma with malignant transformation to adenocarcinoma.
abstract: An anterior mediastinal tumor had been found in a 65-year-old woman 10 years previously, and she had been followed-up under the diagnosis of a mature cystic teratoma. Changes in the structure of the inside of the mediastinal cystic tumor were observed on a chest computed tomography image, and she was referred to our hospital for surgical intervention. The tumor was removed and was determined to be a mature teratoma. An adenocarcinoma was also observed in part of this cystic lesion. From these findings, the lesion was diagnosed as a malignant change in a mediastinal mature teratoma. Because few if any changes tend to be observed in the cystic wall of such cases, an aggressive resection of such mature cystic teratomas is therefore recommended.
authors.affiliation: Department of Surgery, Nihon University School of Medicine, Tokyo, Japan. mura@med.nihon-u.ac.jp
authors.forename: Takashi
authors.initials: T
authors.lastname: Muramatsu
authors.forename: Tatsuhiko
authors.initials: T
authors.lastname: Nishii
authors.forename: Kazumitsu
authors.initials: K
authors.lastname: Ohmori
authors.forename: Motomi
authors.initials: M
authors.lastname: Shiono
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology*; D000368:Aged; D002471:Cell Transformation, Neoplastic; D005260:Female; D006801:Humans; D008479:Mediastinal Neoplasms / Q000473:pathology*; D013724:Teratoma / Q000473:pathology*