title: Infective endocarditis caused by Moraxella nonliquefaciens in a percutaneous aortic valve replacement.
abstract: First case of infective endocarditis on a percutaneous aortic valve replacement due to Moraxalla nonliquefaciens in 64 year old woman. It was successfully treated medically with antibiotics. She had not suitable for surgical aortic valve replacement due to 3 sternotomies for thymoma resection and subsequent radiotherapy with blocked major thoracic veins. Due to her azathioprine immunosuppresion (myasthenia) she may have been at increased endocarditis risk. We suggest prophylactic antibiotics at implant for this group in future.
authors.affiliation: Department Cardiology, Norfolk & Norwich University NHS Hospital.
authors.forename: Isma
authors.initials: I
authors.lastname: Rafiq
authors.affiliation: Department Cardiology, Norfolk & Norwich University NHS Hospital.
authors.forename: Hari
authors.initials: H
authors.lastname: Parthasarathy
authors.affiliation: Department of Microbiology Norfolk & Norwich University NHS Hospital.
authors.forename: Catherine
authors.initials: C
authors.lastname: Tremlett
authors.affiliation: Department Cardiology, Norfolk & Norwich University NHS Hospital. Electronic address: leisa.freeman@nnuh.nhs.uk.
authors.forename: Leisa J
authors.initials: LJ
authors.lastname: Freeman
authors.affiliation: Department of Interventional Cardiology, Royal Brompton Hospital, London.
authors.forename: Michael
authors.initials: M
authors.lastname: Mullin
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001024:Aortic Valve Stenosis / Q000628:therapy*; D001379:Azathioprine / Q000009:adverse effects; D006328:Cardiac Catheterization / Q000009:adverse effects* / Q000295:instrumentation; D004697:Endocarditis, Bacterial / Q000188:drug therapy / Q000382:microbiology*; D005260:Female; D006350:Heart Valve Prosthesis / Q000009:adverse effects*; D019918:Heart Valve Prosthesis Implantation / Q000009:adverse effects* / Q000295:instrumentation; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects; D008875:Middle Aged; D009016:Moraxella / Q000472:pathogenicity*; D045828:Moraxellaceae Infections / Q000188:drug therapy / Q000382:microbiology*; D009157:Myasthenia Gravis / Q000188:drug therapy; D016459:Prosthesis-Related Infections / Q000188:drug therapy / Q000382:microbiology*; D012307:Risk Factors; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D007166:Immunosuppressive Agents; D001379:Azathioprine