title: Clinical studies of dental erosion and erosive wear.
abstract: We define erosion as a partial demineralisation of enamel or dentine by intrinsic or extrinsic acids and erosive tooth wear as the accelerated loss of dental hard tissue through the combined effect of erosion and mechanical wear (abrasion and attrition) on the tooth surface. Most experts believe that during the last decade there has been a significant increase in the prevalence and severity of erosive tooth wear, particularly in adolescents. Even when erosive wear occurs in its milder forms, this is a matter of concern, as it may compromise the integrity of an otherwise healthy dentition in later life. The erosive wear process is complicated and modified by many chemical, behavioural and associated processes in the mouth. If interventions are to be developed it is therefore important that in vivo methods are developed to assess the outcomes of the erosion and erosive wear processes and the effects of interventions upon them. This paper discusses potential methods of investigating erosion and erosive wear in vivo and the difficulties associated with clinical studies.
authors.affiliation: College of Dental Science, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands. m.c.d.n.j.m.huysmans@dent.umcn.nl
authors.forename: M C D N J M
authors.initials: MC
authors.lastname: Huysmans
authors.forename: H P
authors.initials: HP
authors.lastname: Chew
authors.forename: R P
authors.initials: RP
authors.lastname: Ellwood
mesh_terms: D002986:Clinical Trials as Topic; D003743:Dental Enamel / Q000473:pathology; D003804:Dentin / Q000473:pathology; D006801:Humans; D012107:Research Design; D035842:Research Subjects; D014072:Tooth Abrasion / Q000503:physiopathology; D019217:Tooth Attrition / Q000503:physiopathology; D017001:Tooth Demineralization / Q000175:diagnosis / Q000503:physiopathology; D014077:Tooth Erosion / Q000175:diagnosis / Q000503:physiopathology*