title: Evaluation of matrix solid-phase dispersion (MSPD) extraction for multi-mycotoxin determination in different flours using LC-MS/MS.
abstract: An existing matrix solid-phase dispersion (MSPD) method for aflatoxins (AFs) and ochratoxin A (OTA) extraction was extended by further 14 mycotoxins. After it careful optimization, this method was applied to determine the occurrence of these mycotoxins on commercial flour samples (with different cereals composition) collected from local markets. In a total of 49 samples investigated, 9 mycotoxins were identified. Nivalenol (NIV) and Beauvericin (BEA) were the mycotoxins found most frequently. The samples that presented major contamination were wheat flours and bakery preparations. Despite of the great number of positives finding, only one wheat flour sample exceeded the maximum limits (ML) for OTA established by the European Union (EU). However, it would be interesting to calculate the total ingest of these mycotoxins along the years.
authors.affiliation: Department de Medicina Preventiva, Facultat de Farmàcia, Universitat de Valencia, Av. Vicent Andrès Estellès s/n. 46100 Burjassot, Spain.
authors.forename: Josep
authors.initials: J
authors.lastname: Rubert
authors.forename: Carla
authors.initials: C
authors.lastname: Soler
authors.forename: Jordi
authors.initials: J
authors.lastname: Mañes
mesh_terms: D000348:Aflatoxins; D002853:Chromatography, Liquid / Q000379:methods; D002523:Edible Grain; D005433:Flour; D005506:Food Contamination / Q000032:analysis*; D009183:Mycotoxins / Q000032:analysis / Q000302:isolation & purification*; D009793:Ochratoxins; D052616:Solid Phase Extraction / Q000379:methods* / Q000592:standards; D053719:Tandem Mass Spectrometry / Q000379:methods*
chemical_list: D000348:Aflatoxins; D009183:Mycotoxins; D009793:Ochratoxins; C025589:ochratoxin A