title: Dielectric characterization of PCL-based thermoplastic materials for microwave diagnostic and therapeutic applications.
abstract: We propose the use of a polycaprolactone (PCL)-based thermoplastic mesh as a tissue-immobilization interface for microwave imaging and microwave hyperthermia treatment. An investigation of the dielectric properties of two PCL-based thermoplastic materials in the frequency range of 0.5-3.5 GHz is presented. The frequency-dependent dielectric constant and effective conductivity of the PCL-based thermoplastics are characterized using measurements of microstrip transmission lines fabricated on substrates comprised of the thermoplastic meshes. We also examine the impact of the presence of a PCL-based thermoplastic mesh on microwave breast imaging. We use a numerical test bed comprised of a previously reported 3-D anatomically realistic breast phantom and a multi-frequency microwave inverse scattering algorithm. We demonstrate that the PCL-based thermoplastic material and the assumed biocompatible medium of vegetable oil are sufficiently well matched such that the PCL layer may be neglected by the imaging solution without sacrificing imaging quality. Our results suggest that PCL-based thermoplastics are promising materials as tissue immobilization structures for microwave diagnostic and therapeutic applications.
authors.affiliation: Department of Electrical and Computer Engineering, University of Wisconsin, Madison, WI 53706, USA. smaguilar@wisc.edu
authors.forename: Suzette M
authors.initials: SM
authors.lastname: Aguilar
authors.forename: Jacob D
authors.initials: JD
authors.lastname: Shea
authors.forename: Mudar A
authors.initials: MA
authors.lastname: Al-Joumayly
authors.forename: Barry D
authors.initials: BD
authors.lastname: Van Veen
authors.forename: Nader
authors.initials: N
authors.lastname: Behdad
authors.forename: Susan C
authors.initials: SC
authors.lastname: Hagness
mesh_terms: D000465:Algorithms; D001943:Breast Neoplasms / Q000175:diagnosis / Q000532:radiotherapy; D003952:Diagnostic Imaging / Q000295:instrumentation*; D004553:Electric Conductivity; D004867:Equipment Design; D005260:Female; D006801:Humans; D006979:Hyperthermia, Induced / Q000379:methods*; D007103:Immobilization / Q000295:instrumentation*; D008422:Materials Testing; D008872:Microwaves / Q000627:therapeutic use*; D019047:Phantoms, Imaging; D010938:Plant Oils; D011091:Polyesters / Q000737:chemistry*; D012542:Scattering, Radiation
chemical_list: D010938:Plant Oils; D011091:Polyesters; C016240:polycaprolactone