title: Evaluation of spectral domain and time domain optical coherence tomography findings in toxoplasmic retinochoroiditis.
abstract: OBJECTIVE
  To investigate spectral domain optical coherence tomography (SD-OCT) findings and compare them with time domain (TD)-OCT imaging of macula and retinochoroiditis lesions of patients with toxoplasmosis.
  
  
  METHODS
  Prospective cross-sectional study.
  
  
  METHODS
  Ten eyes of 10 patients with active toxoplasmic retinochoroiditis were included. Morphologic features from the macula and retinochoroiditis lesions were obtained at baseline and at 6-week follow up. Scan acquisition protocols for TD-OCT included raster and radial lines through the retinochoroiditis lesion, fast macular, and a linear scan from the lesion to the fovea, whereas the acquisition protocols for SD-OCT also included horizontal volume scans at the lesion site and at the macula. Thickness measurements obtained by SD-OCT were analyzed.
  
  
  RESULTS
  At baseline, macular serous retinal detachment was observed in five patients; two of them only seen by SD-OCT. Retinochoroidal lesions were 4260 μm distant from the fovea on average (R = 681-7130) and this distance had an indirect correlation to the presence of macular detachment. Epiretinal membrane and vitreo-macular traction were also observed. The posterior hyaloid was not identified in four patients by TD-OCT and only in one by SD-OCT at baseline. Perilesional subretinal fluid was observed in two patients. The median retinal thickness significantly decreased at the retinochoroiditis lesion (P = 0.0004), and all the patients remained with disorganized retinal layers reflectivity at follow up.
  
  
  CONCLUSIONS
  SD-OCT is a useful tool in the diagnosis of macular changes related with toxoplasmic retinochoroiditis. SD-OCT is superior in evaluating retinal changes associated with ocular toxoplasmosis.
authors.affiliation: Department of Ophthalmology, Federal University of São Paulo, São Paulo, Brazil. drbrunodiniz@yahoo.com
authors.forename: Bruno
authors.initials: B
authors.lastname: Diniz
authors.forename: Caio
authors.initials: C
authors.lastname: Regatieri
authors.forename: Rafael
authors.initials: R
authors.lastname: Andrade
authors.forename: Andre
authors.initials: A
authors.lastname: Maia