title: Phenolic compounds from Eurycorymbus cavaleriei.
abstract: Three new phenolic compounds, eurycorymboside A (1), eurycorymboside B (6), and eurycorymbic acid (8), were isolated from the stem part of Eurycorymbus cavaleriei (Sapindaceae) along with five known phenolic compounds, glucosyringic acid (2), vanillic acid 4-O-β-d-glucoside (3), koaburaside (4), tachioside (5), and 4-hydroxy-3,5-bis(3-methyl-2-butenyl)benzaldehyde (7). The structures were established on the basis of spectral analysis. The antioxidant activities of compounds 1-6 were evaluated by the 1,1-diphenyl-2-picrylhydrazyl-free radical scavenging assay. Compound 4 exhibited antioxidant activity with an IC(50) value of 9.0 μM. Compound 4 also showed weak inhibitory activity against influenza A neuraminidase.
authors.affiliation: School of Chinese Medicine, The Chinese University of Hong Kong, Hong Kong.
authors.forename: Yi
authors.initials: Y
authors.lastname: He
authors.forename: Li
authors.initials: L
authors.lastname: Zhang
authors.forename: Ming
authors.initials: M
authors.lastname: Zhao
authors.forename: Sam-Hip
authors.initials: SH
authors.lastname: Tsai
authors.forename: Yu-Ying
authors.initials: YY
authors.lastname: Zong
authors.forename: Chun-Tao
authors.initials: CT
authors.lastname: Che
mesh_terms: D000975:Antioxidants / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D000998:Antiviral Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D001713:Biphenyl Compounds / Q000494:pharmacology; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D016166:Free Radical Scavengers / Q000737:chemistry / Q000494:pharmacology; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D009980:Influenza A virus / Q000187:drug effects / Q000201:enzymology; D009439:Neuraminidase / Q000037:antagonists & inhibitors; D010636:Phenols / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D010851:Picrates / Q000494:pharmacology; D018547:Plant Stems / Q000737:chemistry; D029631:Sapindaceae / Q000737:chemistry*
chemical_list: D000975:Antioxidants; D000998:Antiviral Agents; D001713:Biphenyl Compounds; D004365:Drugs, Chinese Herbal; D016166:Free Radical Scavengers; D006027:Glycosides; D010636:Phenols; D010851:Picrates; C560726:eurycorymbic acid; C560724:eurycorymboside A; C560725:eurycorymboside B; C004931:1,1-diphenyl-2-picrylhydrazyl; D009439:Neuraminidase