title: Interdialytic weight gain does not influence the nutrition of new hemodialysis patients.
abstract: OBJECTIVE
  The aim of the present study was to assess the relationship between interdialytic weight gain (IDWG) and nutrition markers in hemodialysis (HD) patients, by means of repeated measures analysis.
  
  
  METHODS
  The records of 255 patients, who had recently received conventional HD for a minimum of 1 year, were retrospectively reviewed. Nutrition markers, including serum albumin, serum phosphate, blood urea nitrogen, and creatinine, were recorded at monthly intervals and subjected to repeated measures analysis.
  
  
  RESULTS
  Patients with higher IDWG/dry weight (IDWG%) (>5%) had significantly lower body mass index throughout the study. Repeated measures analysis of variance indicated no significant difference in these nutrition markers for patients with different IDWG%. At the end of the study, neither IDWG nor IDWG% were found to be associated with albumin or phosphate, on linear regression analysis.
  
  
  CONCLUSIONS
  There was no evidence of better nutrition in new HD patients with higher IDWG%. Although increased intake is promoted as critical for improving nutritional status in HD patients, it may be inappropriate to focus solely on the benefits of higher IDWG%, which can also lead to the development of hypertension, left ventricular hypertrophy, and intradialytic hypotension.
authors.affiliation: Division of Nephrology, Mackay Memorial Hospital, Taipei, Taiwan.
authors.forename: Yu-Wei
authors.initials: YW
authors.lastname: Chen
authors.forename: Han-Hsiang
authors.initials: HH
authors.lastname: Chen
authors.forename: Chi-Feng
authors.initials: CF
authors.lastname: Pan
authors.forename: Chiung-Ying
authors.initials: CY
authors.lastname: Chang
authors.forename: Chih-Jen
authors.initials: CJ
authors.lastname: Wu
mesh_terms: D015992:Body Mass Index; D005260:Female; D006801:Humans; D016014:Linear Models; D008297:Male; D008875:Middle Aged; D009752:Nutritional Status / Q000502:physiology*; D010710:Phosphates / Q000097:blood; D006435:Renal Dialysis; D012189:Retrospective Studies; D012709:Serum Albumin / Q000032:analysis; D015430:Weight Gain
chemical_list: D010710:Phosphates; D012709:Serum Albumin