title: Borderline papillary serous tumor of the fimbriated end of the fallopian tube with peritoneal implants.
abstract: Diagnosis of Borderline papillary serous tumor of the fallopian tube was comprehensively established by Zheng in 1996 supported mostly by a histological similarity to its ovarian counterpart. It is a very rare entity with eight cases published so far and the ninth case described here as a 41-year-old woman presented with non-specific lower abdominal pain, dyspareunia and dysuria. Left adnexal mass was identified and she was operated on. It turned out the tumor was attached exclusively to the left tube, with no connection to any of the surrounding structures and with histology of borderline serous tumor with non-invasive implants in the left and right ovary and visceral peritoneum. Reviewing available data on genetics of these tumors there was diploid status in one examined tumor, and in our case no mutations of KRAS, BRAF and p53 genes were found. Histomorphology remains the mainstay of diagnosis and staging operation is the mainstay of patient management. Prognosis is uncertain with a 6-year survival documented in one case.
authors.affiliation: Sikl's Department of Pathology, University Hospital, Faculty of Medicine, Charles University, Czech Republic. ondic@medima.cz
authors.forename: Ondrej
authors.initials: O
authors.lastname: Ondic
authors.forename: Vladimir
authors.initials: V
authors.lastname: Kalis
authors.forename: Radek
authors.initials: R
authors.lastname: Sima
mesh_terms: D000328:Adult; D018284:Cystadenocarcinoma, Serous / Q000235:genetics / Q000473:pathology* / Q000601:surgery; D005185:Fallopian Tube Neoplasms / Q000235:genetics / Q000473:pathology* / Q000601:surgery; D005187:Fallopian Tubes / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D010534:Peritoneal Neoplasms / Q000235:genetics / Q000473:pathology* / Q000601:surgery; D048493:Proto-Oncogene Proteins B-raf / Q000235:genetics
chemical_list: C482119:BRAF protein, human; D048493:Proto-Oncogene Proteins B-raf