title: Fast and efficient microwave-assisted synthesis of functionalized peptoids via Ugi reactions.
abstract: A wide range of N-alkylglycines (peptoids) can be efficiently prepared via Ugi reactions using microwave irradiations. The results confirm the versatility and efficiency of the methodology for the preparation of functionalized peptoids. The products can be used in consecutive Ugi reactions to yield cyclic peptoids of potential biological interest.
authors.affiliation: Laboratório de Química Metodológica e Orgânica Sintética (LaQMOS), Instituto de Química, Universidade de Brasília, C.P. 4478, 70910-970, Brasília, DF, Brasil.
authors.forename: Angélica de Fátima S
authors.initials: Ade F
authors.lastname: Barreto
authors.forename: Otilie E
authors.initials: OE
authors.lastname: Vercillo
authors.forename: Mike A
authors.initials: MA
authors.lastname: Birkett
authors.forename: John C
authors.initials: JC
authors.lastname: Caulfield
authors.forename: Ludger A
authors.initials: LA
authors.lastname: Wessjohann
authors.forename: Carlos Kleber Z
authors.initials: CK
authors.lastname: Andrade
mesh_terms: D008872:Microwaves; D015394:Molecular Structure; D034444:Peptoids / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D034444:Peptoids