title: Significance of membrane microparticles in solid graft and cellular transplantation.
abstract: Microparticles (MPs) are submicron vesicles released from stimulated or apoptotic cells after plasma membrane remodeling. In body fluids, they constitute relevant hallmarks of cell damage. Having long been considered inert debris reflecting cellular activation or damage, MPs are now considered as cellular effectors involved in cell-cell crosstalk. This review focuses on the pathophysiologic significance of MPs in the particular setting of solid graft and cellular transplantation.
authors.affiliation: Hopitaux Universitaires de Strasbourg, Pole de Cardiologie et de chirurgie cardiovasculaire, Strasbourg, France.
authors.forename: Babe
authors.initials: B
authors.lastname: Bakouboula
authors.forename: Olivier
authors.initials: O
authors.lastname: Morel
authors.forename: Anne-Laure
authors.initials: AL
authors.lastname: Faller
authors.forename: Jean-Marie
authors.initials: JM
authors.lastname: Freyssinet
authors.forename: Florence
authors.initials: F
authors.lastname: Toti
mesh_terms: D000818:Animals; D001808:Blood Vessels / Q000502:physiology; D055252:Cell-Derived Microparticles / Q000187:drug effects / Q000502:physiology*; D006801:Humans; D007166:Immunosuppressive Agents / Q000494:pharmacology; D008954:Models, Biological; D013312:Stress, Physiological; D019737:Transplants
chemical_list: D007166:Immunosuppressive Agents