title: Theory of mind and facial emotion recognition in euthymic bipolar I and bipolar II disorders.
abstract: The main aim of this study was to compare patients with euthymic bipolar I (BDI) and bipolar II (BDII) disorders and healthy controls in measures of social cognition. Additional aims were to explore the association between social cognition performance with neurocognitive impairments and psychosocial functioning. Eighty one euthymic patients with BDI or BDII and 34 healthy controls were included. All subjects completed tests to assess verbal memory, attention, and executive functions. Additionally theory of mind (ToM) and facial emotion recognition measures were included. Psychosocial functioning was assessed with the GAF. Both groups of patients had lower performance than healthy controls in ToM, and a lower recognition of fear facial expression. When neurocognitive impairments and exposure to medications were controlled, performance in ToM and recognition of fear facial expression did not allow predicting if a subject was patient or healthy control. Social cognition measures not enhance variance beyond explained by neurocognitive impairments and they were not independent predictors of psychosocial functioning. Impairments in facial emotion recognition and ToM are mediated, at least partly, by attention-executive functions deficits and exposure to psychotropic medications. Likewise, social cognition measures did not contribute to variance beyond neurocognitive impairments.
authors.affiliation: Bipolar Disorders Program, Department of Psychiatry, Neuroscience Institute, Favaloro University, Buenos Aires, Argentina.
authors.forename: Diego Javier
authors.initials: DJ
authors.lastname: Martino
authors.forename: Sergio Adrián
authors.initials: SA
authors.lastname: Strejilevich
authors.forename: Guillermo
authors.initials: G
authors.lastname: Fassi
authors.forename: Eliana
authors.initials: E
authors.lastname: Marengo
authors.forename: Ana
authors.initials: A
authors.lastname: Igoa
mesh_terms: D000293:Adolescent; D000328:Adult; D000704:Analysis of Variance; D001288:Attention / Q000502:physiology; D001714:Bipolar Disorder / Q000145:classification / Q000150:complications / Q000523:psychology; D003072:Cognition Disorders / Q000209:etiology* / Q000523:psychology; D056344:Executive Function / Q000502:physiology; D005149:Facial Expression; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D011569:Psychiatric Status Rating Scales; D021641:Recognition, Psychology / Q000502:physiology*; D056345:Theory of Mind; D055815:Young Adult