title: Promoting the effect of chemical constituents from the flowers of Poacynum                      hendersonii on adipogenesis in 3T3-L1 cells.
abstract: A novel sugar ester poacynose (1) was isolated from the flowers of Poacynum hendersonii together with 31 known compounds. The structure of 1 was established mainly on the basis of 1D and 2D NMR spectral data. Among the isolates, several constituents, such as kaempferol 3-O-sophoroside (5), picein (16), and 4-hydroxybenzoic acid 4-O-β-D-glucopyranoside (17) moderately promoted adipogenesis of 3T3-L1 cells. In addition, simultaneous quantitative analysis of eight flavonoid constituents from the flower and leaf parts of P. hendersonii was developed.
authors.affiliation: Pharmaceutical Research and Technology Institute, Kinki University, 3-4-1 Kowakae, Higashi-osaka, Osaka 577-8502, Japan. morikawa@kindai.ac.jp
authors.forename: Toshio
authors.initials: T
authors.lastname: Morikawa
authors.forename: Katsuya
authors.initials: K
authors.lastname: Imura
authors.forename: Sohachiro
authors.initials: S
authors.lastname: Miyake
authors.forename: Kiyofumi
authors.initials: K
authors.lastname: Ninomiya
authors.forename: Hisashi
authors.initials: H
authors.lastname: Matsuda
authors.forename: Chihiro
authors.initials: C
authors.lastname: Yamashita
authors.forename: Osamu
authors.initials: O
authors.lastname: Muraoka
authors.forename: Takao
authors.initials: T
authors.lastname: Hayakawa
authors.forename: Masayuki
authors.initials: M
authors.lastname: Yoshikawa
mesh_terms: D041721:3T3-L1 Cells; D017667:Adipocytes / Q000187:drug effects* / Q000378:metabolism; D050156:Adipogenesis / Q000187:drug effects*; D000818:Animals; D029062:Apocynaceae / Q000737:chemistry; D002851:Chromatography, High Pressure Liquid; D004952:Esters / Q000494:pharmacology; D005419:Flavonoids / Q000494:pharmacology; D035264:Flowers; D009682:Magnetic Resonance Spectroscopy; D051379:Mice; D015394:Molecular Structure; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D018515:Plant Leaves; D014280:Triglycerides / Q000378:metabolism
chemical_list: D004952:Esters; D005419:Flavonoids; D010936:Plant Extracts; D014280:Triglycerides