title: Thirty years of multiple sequence codes.
abstract: An overview is presented on the status of studies on multiple codes in genetic sequences. Indirectly, the existence of multiple codes is recognized in the form of several rediscoveries of Second Genetic Code that is different each time. A due credit is given to earlier seminal work related to the codes often neglected in literature. The latest developments in the field of chromatin code are discussed, as well as perspectives of single-base resolution studies of nucleosome positioning, including rotational setting of DNA on the surface of the histone octamers.
authors.affiliation: Genome Diversity Center, Institute of Evolution, University of Haifa, Haifa, Israel. trifonov@research.haifa.ac.il
authors.forename: Edward N
authors.initials: EN
authors.lastname: Trifonov
mesh_terms: D000818:Animals; D001483:Base Sequence; D002843:Chromatin / Q000235:genetics / Q000378:metabolism; D042002:Chromatin Assembly and Disassembly; D005815:Genetic Code; D006801:Humans; D009707:Nucleosomes / Q000378:metabolism; D012045:Regulatory Sequences, Nucleic Acid; D017422:Sequence Analysis, DNA
chemical_list: D002843:Chromatin; D009707:Nucleosomes