title: Gold nanomaterials as a new tool for bioanalytical applications of laser desorption ionization mass spectrometry.
abstract: Nanomaterials have emerging importance in laser desorption ionization mass spectrometry (LDI-MS) with the ultimate objective being to overcome some of the most important limitations intrinsically related to the use of conventional organic matrices in matrix-assisted (MA) LDI-MS. This review provides a critical overview of the most recent literature on the use of gold nanomaterials as non-conventional desorption ionization promoters in LDI-MS, with particular emphasis on bioanalytical applications. Old seminal papers will also be discussed to provide a timeline of the most significant achievements in the field. Future prospects and research needs are also briefly discussed.
authors.affiliation: Dipartimento di Chimica, Università degli Studi di Bari Aldo Moro, Bari, Italy.
authors.forename: Rosa
authors.initials: R
authors.lastname: Pilolli
authors.forename: Francesco
authors.initials: F
authors.lastname: Palmisano
authors.forename: Nicola
authors.initials: N
authors.lastname: Cioffi
mesh_terms: D001681:Biological Assay; D006046:Gold / Q000737:chemistry*; D053768:Metal Nanoparticles / Q000737:chemistry*; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / Q000379:methods*
chemical_list: D006046:Gold