title: Mycobacterium heckeshornense lung infection that was diagnosed as Mycobacterium xenopi disease by DNA-DNA hybridization (DDH).
abstract: The DNA sequencing analyses of the 16S rRNA gene, rpoB and hsp65 were conducted to characterize six strains that had been identified as Mycobacterium xenopi by DNA-DNA hybridization (DDH) for past ten years in our hospital. The results revealed Mycobacterium heckeshornense infection in one of the six cases. A 47-year-old man, who had been treated for pneumonia, had pulmonary nontuberculous mycobacterial disease. The sputa from the patient were culture positive for mycobacterium in three times. And it was diagnosed as M. xenopiby DDH method. Chest X-ray showed fibrocavitary lesion in right upper lobe was successfully treated with clarithromycin for four weeks.
authors.affiliation: Fukujuji Hospital, Japan Anti-tuberculosis Association, Japan. bxypb621@ybb.ne.jp
authors.forename: Kozo
authors.initials: K
authors.lastname: Morimoto
authors.forename: Yuko
authors.initials: Y
authors.lastname: Kazumi
authors.forename: Shinji
authors.initials: S
authors.lastname: Maeda
authors.forename: Kozo
authors.initials: K
authors.lastname: Yoshimori
authors.forename: Takashi
authors.initials: T
authors.lastname: Yoshiyama
authors.forename: Hideo
authors.initials: H
authors.lastname: Ogata
authors.forename: Atsuyuki
authors.initials: A
authors.lastname: Kurashima
authors.forename: Shoji
authors.initials: S
authors.lastname: Kudoh
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D017291:Clarithromycin / Q000627:therapeutic use; D015342:DNA Probes; D004269:DNA, Bacterial / Q000235:genetics; D003937:Diagnosis, Differential; D006801:Humans; D007564:Japan; D008168:Lung / Q000382:microbiology; D008171:Lung Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology*; D008297:Male; D008875:Middle Aged; D009161:Mycobacterium / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification; D009164:Mycobacterium Infections / Q000175:diagnosis* / Q000188:drug therapy; D009165:Mycobacterium Infections, Nontuberculous / Q000175:diagnosis* / Q000188:drug therapy; D019912:Mycobacterium xenopi / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification; D013045:Species Specificity; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D015342:DNA Probes; D004269:DNA, Bacterial; D017291:Clarithromycin