title: Quantitative structure-activity relationship of Morita-Baylis-Hillman adducts with leishmanicidal activity.
abstract: A quantitative structure-activity relationship model for Morita-Baylis-Hillman adducts with leishmanicidal activities was developed which correlates molecular orbital energy and dipole with percentage in the promastigote stage.
authors.affiliation: Instituto de Química, Universidade Federal do Rio de Janeiro, Av. Athos da Silveira Ramos 146, 21944-910, Rio de Janeiro, Brazil. rodrigosouza@iq.ufrj.br
authors.forename: Rodrigo Octavio M A
authors.initials: RO
authors.lastname: de Souza
authors.forename: José C
authors.initials: JC
authors.lastname: Barros
authors.forename: Joaquim F M
authors.initials: JF
authors.lastname: da Silva
authors.forename: Octavio A C
authors.initials: OA
authors.lastname: Antunes
mesh_terms: D000818:Animals; D000981:Antiprotozoal Agents / Q000737:chemistry* / Q000494:pharmacology*; D007891:Leishmania / Q000187:drug effects*; D008962:Models, Theoretical; D021281:Quantitative Structure-Activity Relationship
chemical_list: D000981:Antiprotozoal Agents