title: [The study on the changes of serum IL- 6, TNF-α and peripheral blood T lymphocyte subsets in the pregnant women during perinatal period].
abstract: OBJECTIVE
  To study the change law of serum IL-6, TNF-α and peripheral blood T lymphocyte subsets in the pregnant women during perinatal period.
  
  
  METHODS
  100 pregnant women in our hospital from November 2009 to October 2010 were selected as research object, and the serum IL-6, TNF-α and peripheral blood T lymphocyte subsets be-fore and at labor onset occurring, after delivery at the first and third day were analyzed and compared.
  
  
  RESULTS
  According the study, the serum IL-6 and TNF-aat labor onset occurring were higher than those before labor onset and af-ter delivery at the first and third day , the CD3(+), CD4 (+), CD8(+) and CD4/CD8 decreased first and then increased, all P < 0. 05, there were significant differences.
  
  
  CONCLUSIONS
  The changes of serum IL-6, TNF-α and peripheral blood T lymphocyte subsets in the pregnant women during perinatal period has a regular pattern, and it is worthy of.
authors.affiliation: The Departmet of Basic Medicine of Xuchang Medicine School, Xuchang 461000, China.
authors.forename: Juan
authors.initials: J
authors.lastname: Li
mesh_terms: D016516:CD4-CD8 Ratio; D015496:CD4-Positive T-Lymphocytes / Q000378:metabolism*; D018414:CD8-Positive T-Lymphocytes / Q000378:metabolism*; D016207:Cytokines / Q000097:blood; D005260:Female; D006801:Humans; D015850:Interleukin-6 / Q000032:analysis*; D036801:Parturition; D058725:Peripartum Period; D011247:Pregnancy / Q000097:blood*; D044967:Serum / Q000737:chemistry; D016176:T-Lymphocyte Subsets / Q000378:metabolism*; D014409:Tumor Necrosis Factor-alpha / Q000097:blood*
chemical_list: D016207:Cytokines; D015850:Interleukin-6; D014409:Tumor Necrosis Factor-alpha