title: Monitoring of organochlorine pesticide residue levels in adipose tissue of Veracruz, Mexico inhabitants.
abstract: The objective of the present study was to monitor the levels of organochlorine pesticides HCB, α-β-γ-HCH, pp'DDE, op'DDT and pp'DDT in 150 adipose tissue samples of Veracruz, Mexico inhabitants. In analyzed samples, the following pesticides were detected: p,p'-DDE in 100% of the samples at mean 1.643 mg/kg; p,p'-DDT in 99.3.% of the samples at mean 0.227 mg/kg; β-HCH in 97.3% of the samples at mean 0.063 mg/kg; and op'DDT in 93.3% of the samples at mean 0.022 mg/kg. Comparing mean, median and geometric mean concentrations of organochlorine pesticides shows a decrease in values from mean to median and to geometric mean which points out a prevalence of lower concentrations among the total samples and the existence of occasional cases of extreme exposure expressed in range values. The pooled samples divided according to sex, showed only significant differences of pp'DDE median concentrations between sexes. The other organochlorine pesticides indicated no statistical differences between sexes, including the pp'DDE/pp'DDT ratio. The samples grouped according to age, showed that the third tertile was more contaminated for both sexes, indicating age as a positively associated factor with organochlorine pesticide levels in adipose tissue of Veracruz inhabitants. Comparing organochlorine pesticide levels between 2008 and 2010 years, a decreased tendency for β-HCH, pp'DDE, Σ-DDT and pp'DDE/pp'DDT ratio levels was observed.
authors.affiliation: Institute of Forensic Medicine, University of Veracruz, SS Juan Pablo II s/n, 91980 Boca del Río, Ver, Mexico. swal@uv.mx
authors.forename: Stefan M
authors.initials: SM
authors.lastname: Waliszewski
authors.forename: M
authors.initials: M
authors.lastname: Caba
authors.forename: M
authors.initials: M
authors.lastname: Herrero-Mercado
authors.forename: H
authors.initials: H
authors.lastname: Saldariaga-Noreña
authors.forename: E
authors.initials: E
authors.lastname: Meza
authors.forename: R
authors.initials: R
authors.lastname: Zepeda
authors.forename: C
authors.initials: C
authors.lastname: Martínez-Valenzuela
authors.forename: R
authors.initials: R
authors.lastname: Infanzon
authors.forename: F
authors.initials: F
authors.lastname: Hernández-Chalate
mesh_terms: D000273:Adipose Tissue / Q000378:metabolism*; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003634:DDT / Q000378:metabolism; D003633:Dichlorodiphenyl Dichloroethylene / Q000378:metabolism; D004781:Environmental Exposure / Q000032:analysis* / Q000706:statistics & numerical data; D004785:Environmental Pollutants / Q000378:metabolism*; D005260:Female; D001556:Hexachlorocyclohexane / Q000378:metabolism; D006801:Humans; D006843:Hydrocarbons, Chlorinated / Q000378:metabolism*; D008297:Male; D008800:Mexico; D008875:Middle Aged; D010573:Pesticide Residues / Q000378:metabolism*; D055815:Young Adult
chemical_list: D004785:Environmental Pollutants; D006843:Hydrocarbons, Chlorinated; D010573:Pesticide Residues; C040534:alpha-hexachlorocyclohexane; D003633:Dichlorodiphenyl Dichloroethylene; D001556:Hexachlorocyclohexane; D003634:DDT; C023888:beta-hexachlorocyclohexane