title: Six weeks of aerobic dance exercise improves blood oxidative stress status and increases interleukin-2 in previously sedentary women.
abstract: This study evaluated the change in blood oxidative stress, blood interleukin-2, and physical performance following 6 weeks of moderate intensity and duration aerobic dance exercise in 24 sedentary women. Blood samples were collected at rest twice before (baseline) and after the 6-week intervention for analysis of protein hydroperoxide (PrOOH), malondialdehyde (MDA), total anti-oxidant capacity (TAC), and interleukin-2 (IL-2) levels. Maximal treadmill run time (Time(max)) and maximal oxygen consumption (VO(2max)) were also measured. All variables were statistically analyzed with a repeated measurement ANOVA and Tukey post hoc. No differences were noted in any variable during the baseline period (p > 0.05). After aerobic dance exercise, VO(2max), Time(max), TAC and IL-2 were significantly increased, whereas MDA levels were decreased significantly (p < 0.05). PrOOH did not change either between baseline measures or after exercise. It can be concluded that aerobic dance exercise at a moderate intensity and duration can improve physical fitness, decrease MDA, and increase TAC and IL-2 in previously sedentary women.
authors.affiliation: Oxidative Stress and Exercise Biochemistry Laboratory, Department of Physical Therapy, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai 50200, Thailand. nuttakan@chiangmai.ac.th
authors.forename: Donrawee
authors.initials: D
authors.lastname: Leelarungrayub
authors.forename: Kunteera
authors.initials: K
authors.lastname: Saidee
authors.forename: Prapas
authors.initials: P
authors.lastname: Pothongsunun
authors.forename: Sainetee
authors.initials: S
authors.lastname: Pratanaphon
authors.forename: Araya
authors.initials: A
authors.lastname: YanKai
authors.forename: Richard J
authors.initials: RJ
authors.lastname: Bloomer
mesh_terms: D000328:Adult; D000975:Antioxidants / Q000627:therapeutic use; D003615:Dancing / Q000502:physiology*; D015444:Exercise / Q000502:physiology*; D005080:Exercise Test; D005260:Female; D006339:Heart Rate; D006801:Humans; D007376:Interleukin-2 / Q000096:biosynthesis / Q000097:blood*; D008315:Malondialdehyde / Q000097:blood; D008875:Middle Aged; D018384:Oxidative Stress; D010101:Oxygen Consumption / Q000502:physiology*; D057185:Sedentary Behavior; D013647:Task Performance and Analysis; D013997:Time Factors
chemical_list: D000975:Antioxidants; D007376:Interleukin-2; D008315:Malondialdehyde