title: Acute kidney injury complicating septic unsafe abortion: clinical course and treatment outcomes of 44 cases.
abstract: OBJECTIVE
  The aim of this study was to present the clinical course and treatment outcomes of patients with acute kidney injury (AKI) after septic unsafe abortion.
  
  
  METHODS
  Medical records of patients with AKI after septic unsafe abortion admitted at Khon Kaen Hospital between January 2003 and December 2009 were reviewed.
  
  
  RESULTS
  Forty-four patients with an average age of 24.3 years were included and 25% were teenage girls. The most common method of induced abortion was transvaginal chemical injection (81.8%). One patient had a hysterectomy due to severe peritonitis and sepsis that was not responsive to medical treatment. AKI developed on day 4.5 ± 3.6 with the range of onset 1-14 days after induced abortion. Oliguric AKI was present in 70.4% of patients with the mean duration of oliguria of 7.4 ± 5 days. Seventeen patients required dialysis. The mortality rate was 9%. The average duration of recovery from AKI was 24.8 ± 16.6 days.
  
  
  CONCLUSIONS
  Conservative treatment of AKI-related septic unsafe abortion was dialysis without hysterectomy. The treatment results were minimal morbidity and mortality. Conservative management may be a better alternative to hysterectomy for the treatment of septic unsafe abortion with AKI. However the current study was a retrospective study, and we were not able to obtain certain follow-up data, such as fertility outcomes after recovery. Therefore, further study of these issues should be considered.
authors.affiliation: Department of Obstetrics and Gynecology, Khon Kaen Hospital, Khon Kaen, Thailand. sbudsanom@hotmail.com
authors.forename: Sukanya
authors.initials: S
authors.lastname: Srinil
authors.forename: Thanachai
authors.initials: T
authors.lastname: Panaput
mesh_terms: D000031:Abortion, Septic / Q000628:therapy*; D058186:Acute Kidney Injury / Q000209:etiology* / Q000628:therapy; D000293:Adolescent; D000328:Adult; D005260:Female; D017052:Hospital Mortality; D006801:Humans; D011247:Pregnancy; D006435:Renal Dialysis; D012189:Retrospective Studies; D013785:Thailand; D016896:Treatment Outcome