title: [Biphosphonate-induced femoral stress fractures :  A new problem and knowledge so far - case report].
abstract: During the last several years the treatment of osteoporosis with bisphosphonates has become accepted as a safe and effective procedure. However, recently there have been increasing numbers of reports of rare complications in the literature. Particularly the occurrence of atypical fractures of the femur has become a focus of interest but the problem is insufficiently known and only rarely addressed in the scientific discussion. The case illustrated here and a survey of the important facts in the recent literature highlight essential aspects of long-term bisphosphonate therapy.
authors.affiliation: Orthopädische Klinik und Poliklinik, Universitätsklinikum Rostock, Doberanerstr. 142, 18057, Rostock, Deutschland. robert.lenz@med.uni-rostock.de
authors.forename: R
authors.initials: R
authors.lastname: Lenz
authors.forename: M
authors.initials: M
authors.lastname: Ellenrieder
authors.forename: R
authors.initials: R
authors.lastname: Skripitz
authors.forename: R
authors.initials: R
authors.lastname: Bader
authors.forename: C
authors.initials: C
authors.lastname: Pautke
authors.forename: W
authors.initials: W
authors.lastname: Mittelmeier
authors.forename: T
authors.initials: T
authors.lastname: Tischer
mesh_terms: D000368:Aged; D059266:Bisphosphonate-Associated Osteonecrosis of the Jaw / Q000000981:diagnostic imaging* / Q000209:etiology*; D004164:Diphosphonates / Q000009:adverse effects*; D005260:Female; D005264:Femoral Fractures / Q000139:chemically induced* / Q000000981:diagnostic imaging*; D015775:Fractures, Stress / Q000139:chemically induced* / Q000000981:diagnostic imaging*; D006801:Humans; D011859:Radiography
chemical_list: D004164:Diphosphonates