title: Hyaluronic acid gel in the treatment of empty nose syndrome.
abstract: BACKGROUND
  Empty nose syndrome (ENS) along with atrophic rhinitis are disease entities that are bothersome for patients and difficult for their doctors to treat. The purpose of this study was to evaluate the usefulness of intranasal injection of hyaluronic acid (HA) gel in patients with symptoms of ENS.
  
  
  METHODS
  Three patients suffering from ENS and atrophic rhinitis underwent trial treatment consisting of submucosal injections of HA preparations into the inferior nasal concha and under the mucous membrane of the septum.
  
  
  RESULTS
  As a result of treatment, the patients' symptoms improved for several months and no complications were recorded.
  
  
  CONCLUSIONS
  Because of its simplicity, safety, and fairly good, but impermanent clinical effects, HA injections appear to be worth considering in less severe forms of ENS.
authors.affiliation: Section of Aesthetic Medicine, Polish Medical Society, The Regional Otolaryngology and Allergology Outpatient "PIAST," Grudziadz, Poland. mmodrzynski@interia.pl
authors.forename: Marek
authors.initials: M
authors.lastname: Modrzyński
mesh_terms: D000015:Abnormalities, Multiple / Q000188:drug therapy* / Q000503:physiopathology; D005260:Female; D005782:Gels / Q000008:administration & dosage / Q000009:adverse effects; D006261:Headache; D006801:Humans; D006820:Hyaluronic Acid / Q000008:administration & dosage* / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D009297:Nasal Mucosa / Q000187:drug effects / Q000473:pathology; D015508:Nasal Obstruction; D009300:Nasal Septum / Q000187:drug effects* / Q000473:pathology; D012222:Rhinitis, Atrophic / Q000188:drug therapy* / Q000503:physiopathology; D013577:Syndrome; D014420:Turbinates / Q000187:drug effects* / Q000473:pathology; D055675:Viscosupplements / Q000008:administration & dosage / Q000009:adverse effects
chemical_list: D005782:Gels; D055675:Viscosupplements; D006820:Hyaluronic Acid