title: Microfluidics made of yarns and knots: from fundamental properties to simple networks and operations.
abstract: We present and characterize cotton yarn and knots as building blocks for making microfluidic circuits from the bottom up. The yarn used is made up of 200-300 fibres, each with a lumen. Liquid applied at the extremity of the yarn spontaneously wets the yarn, and the wetted length increases linearly over time in untreated yarn, but progresses according to a square root relationship as described by Washburn's equation upon plasma activation of the yarn. Knots are proposed for combining, mixing and splitting streams of fluids. Interestingly, the topology of the knot controls the mixing ratio of two inlet streams into two outlet yarns, and thus the ratio can be adjusted by choosing a specific knot. The flow resistance of a knot is shown to depend on the force used to tighten it and the flow resistance rapidly increases for single-stranded knots, but remains low for double-stranded knots. Finally, a serial dilutor is made with a web made of yarns and double-stranded overhand knots. These results suggest that yarn and knots may be used to build low cost microfluidic circuits.
authors.affiliation: Biomedical Engineering Department, McGill University, 740 Dr Penfield Avenue, Montreal, QC H3A 1A4, Canada.
authors.forename: Roozbeh
authors.initials: R
authors.lastname: Safavieh
authors.forename: Gina Z
authors.initials: GZ
authors.lastname: Zhou
authors.forename: David
authors.initials: D
authors.lastname: Juncker
mesh_terms: D046210:Microfluidic Analytical Techniques / Q000295:instrumentation / Q000379:methods*; D008962:Models, Theoretical; D009757:Nylons
chemical_list: D009757:Nylons