title: Validation of completeness, correctness, relevance and understandability of the PSIP CDSS for medication safety.
abstract: Medication errors and resulting Adverse Drug Events (ADEs) are an important issue of global healthcare. Within the European PSIP project that aims at developing solutions to improve medication safety, contextualized decision support modules aiming to prevent ADEs are being developed. The objective of this work was to thoroughly validate part of the CDSS (Clinical Decision Support System) and the underlying Knowledge Base, in order to detect incorrect or unclear alerts. We systematically developed a repository of test cases and used them for validation. The development of the test cases showed that there are differences among experts in interpreting the correctness of an alert, and that the clinical context is important when judging whether it is adequate. Overall, validation did not find major errors in the Knoweldge Base, but developed several recommendations for further improvement.
authors.affiliation: Institute for Health Information Systems, UMIT - University for Health Sciences, Medical Informatics and Technology, Hall in Tyrol, Austria. elske.ammenwerth@umit.at
authors.forename: Elske
authors.initials: E
authors.lastname: Ammenwerth
authors.forename: Werner O
authors.initials: WO
authors.lastname: Hackl
authors.forename: Philippe
authors.initials: P
authors.lastname: Massari
authors.forename: Stefan
authors.initials: S
authors.lastname: Darmoni
mesh_terms: D020000:Decision Support Systems, Clinical / Q000458:organization & administration*; D064420:Drug-Related Side Effects and Adverse Reactions / Q000517:prevention & control; D006801:Humans; D051188:Knowledge Bases; D050316:Medical Order Entry Systems / Q000458:organization & administration*; D008508:Medication Errors / Q000517:prevention & control*; D017010:Reminder Systems; D012986:Software Validation