title: The Pre-diabetes Risk Education and Physical Activity Recommendation and Encouragement (PREPARE) programme study: are improvements in glucose regulation sustained at 2 years?
abstract: OBJECTIVE
  To determine whether improvements in glucose regulation following the PREPARE structured education programme were sustained at 24 months.
  
  
  METHODS
  Ninety-eight overweight or obese individuals with impaired glucose tolerance were randomized to receive: (1) advice leaflet, (2) 3-h structured education programme aimed at promoting physical activity, (iii) 3-h structured education with personalized pedometer use. The primary outcome was change in 2-h post-challenge plasma glucose.
  
  
  RESULTS
  Seventy-three (74%) individuals were included for analysis at 24 months; age 65 ± 8 years, BMI 29.3 ± 4.8 kg/m(2), South Asian ethnicity 21%. A statistically significant reduction in 2-h glucose of -1.6 mmol/l (-0.4 to -2.7) was seen in the education-with-pedometer group compared with the control group. There is no significant difference in the education-only group.
  
  
  CONCLUSIONS
  Improvements in glucose regulation following a pragmatic group-based structured education with pedometer use were sustained at 24 months.
authors.affiliation: Department of Cardiovascular Sciences, University of Leicester, Leicester, UK. ty20@le.ac.uk
authors.forename: T
authors.initials: T
authors.lastname: Yates
authors.forename: M J
authors.initials: MJ
authors.lastname: Davies
authors.forename: S
authors.initials: S
authors.lastname: Sehmi
authors.forename: T
authors.initials: T
authors.lastname: Gorely
authors.forename: K
authors.initials: K
authors.lastname: Khunti
mesh_terms: D000368:Aged; D015992:Body Mass Index; D003924:Diabetes Mellitus, Type 2 / Q000517:prevention & control / Q000523:psychology*; D005260:Female; D005500:Follow-Up Studies; D018149:Glucose Intolerance / Q000150:complications / Q000503:physiopathology / Q000523:psychology*; D007722:Health Knowledge, Attitudes, Practice; D006293:Health Promotion; D006801:Humans; D008297:Male; D008875:Middle Aged; D009043:Motor Activity; D009765:Obesity / Q000150:complications / Q000503:physiopathology / Q000523:psychology*; D010353:Patient Education as Topic; D011236:Prediabetic State / Q000523:psychology*; D055105:Waist Circumference; D016138:Walking