title: [Multiple mononeuritis in a patient with Churg-Strauss syndrome. Pseudo conduction block as an early electroclinical expression].
abstract: BACKGROUND
  Multiple mononeuritis is one of the most frequent manifestations of Churg-Strauss syndrome.
  
  
  METHODS
  We describe a case of acute sensory-motor multiple mononeuritis in all four limbs of a 53-year-old male with Churg-Strauss syndrome. Electrodiagnosis performed within the first seven days revealed conduction blocks in several nerves. Follow-up studies showed diffuse bilateral sensory-motor axonal polyneuropathy with symmetries, but without blocks. Electrophysiological and histological analyses, together with experimental studies, showed it to be an axonopathy secondary to acute ischaemia.
  
  
  CONCLUSIONS
  In only a few cases, such as this one and in a small number of incipient studies, have there been reports of conduction blocks that, owing to the fact that they are commonly related with demyelination, give rise to confusion when it comes to diagnoses and prognoses. The condition usually displays axonopathy due to Wallerian degeneration. It therefore seems recommendable in these cases to proceed with caution and to perform neurophysiological studies in the following weeks in order to prevent inappropriate diagnostic and prognostic judgements from being formed.
authors.affiliation: Unidad de Electromiografía Clínica, Servicio de Neurofisiología, Albacete, España. josempardal@yahoo.es
authors.forename: José M
authors.initials: JM
authors.lastname: Pardal-Fernandez
authors.forename: Begoña
authors.initials: B
authors.lastname: Godes-Medrano
authors.forename: Pedro
authors.initials: P
authors.lastname: Sánchez-Ayaso
authors.forename: María
authors.initials: M
authors.lastname: Rodríguez-Vázquez
authors.forename: Luis
authors.initials: L
authors.lastname: Iñíguez-De Onzoño
mesh_terms: D015267:Churg-Strauss Syndrome / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology*; D004568:Electrodiagnosis; D006801:Humans; D008297:Male; D008875:Middle Aged; D020422:Mononeuropathies / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology*; D009431:Neural Conduction / Q000502:physiology*