title: Emerging severe and fatal infections due to Klebsiella pneumoniae in two university hospitals in France.
abstract: Severe infections caused by hypermucoviscous Klebsiella pneumoniae have been reported in Southeast Asian countries over the past several decades. This report shows their emergence in France, with 12 cases observed during a 2-year period in two university hospitals. Two clones (sequence type 86 [ST86] and ST380) of serotype K2 caused five rapidly fatal bacteremia cases, three of which were associated with pneumonia, whereas seven liver abscess cases were caused by K1 strains of ST23.
authors.affiliation: Laboratoire de Bactériologie, Hôpital Saint-Antoine, 184 rue du Faubourg Saint-Antoine, 75012 Paris, France. dominique.decre@sat.aphp.fr
authors.forename: Dominique
authors.initials: D
authors.lastname: Decré
authors.forename: Charlotte
authors.initials: C
authors.lastname: Verdet
authors.forename: Aurélie
authors.initials: A
authors.lastname: Emirian
authors.forename: Thibault
authors.initials: T
authors.lastname: Le Gourrierec
authors.forename: Jean-Claude
authors.initials: JC
authors.lastname: Petit
authors.forename: Georges
authors.initials: G
authors.lastname: Offenstadt
authors.forename: Eric
authors.initials: E
authors.lastname: Maury
authors.forename: Sylvain
authors.initials: S
authors.lastname: Brisse
authors.forename: Guillaume
authors.initials: G
authors.lastname: Arlet
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016470:Bacteremia / Q000453:epidemiology / Q000401:mortality / Q000473:pathology; D005602:France / Q000453:epidemiology; D006785:Hospitals, University; D006801:Humans; D007710:Klebsiella Infections / Q000453:epidemiology* / Q000401:mortality* / Q000473:pathology; D007711:Klebsiella pneumoniae / Q000145:classification* / Q000235:genetics / Q000276:immunology / Q000302:isolation & purification*; D008100:Liver Abscess / Q000453:epidemiology / Q000401:mortality / Q000473:pathology; D008875:Middle Aged; D058889:Molecular Typing; D018410:Pneumonia, Bacterial / Q000453:epidemiology / Q000401:mortality / Q000473:pathology; D012703:Serotyping