title: Niclosamide: an established antihelminthic drug as a potential therapy against S100A4-mediated metastatic colon tumors.
authors.forename: David M
authors.initials: DM
authors.lastname: Helfman
mesh_terms: D000818:Animals; D000871:Anthelmintics / Q000494:pharmacology; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology*; D014408:Biomarkers, Tumor / Q000235:genetics / Q000378:metabolism*; D045744:Cell Line, Tumor; D002465:Cell Movement / Q000187:drug effects; D003110:Colonic Neoplasms / Q000188:drug therapy* / Q000378:metabolism* / Q000473:pathology; D018450:Disease Progression; D015972:Gene Expression Regulation, Neoplastic / Q000187:drug effects; D006801:Humans; D008113:Liver Neoplasms / Q000517:prevention & control* / Q000556:secondary; D051379:Mice; D009361:Neoplasm Invasiveness; D009534:Niclosamide / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology*; D011379:Prognosis; D012333:RNA, Messenger / Q000378:metabolism; D000071999:S100 Calcium-Binding Protein A4; D009418:S100 Proteins / Q000235:genetics / Q000378:metabolism*; D015398:Signal Transduction / Q000187:drug effects; D014183:Transplantation, Heterologous; D051153:Wnt Proteins / Q000187:drug effects / Q000378:metabolism; D051176:beta Catenin / Q000187:drug effects / Q000378:metabolism
chemical_list: D000871:Anthelmintics; D000970:Antineoplastic Agents; D014408:Biomarkers, Tumor; C495270:CTNNB1 protein, human; D012333:RNA, Messenger; D000071999:S100 Calcium-Binding Protein A4; D009418:S100 Proteins; D051153:Wnt Proteins; D051176:beta Catenin; C077591:S100A4 protein, human; D009534:Niclosamide