title: Autophagy facilitates an IFN-γ response and signal transduction.
abstract: Autophagy, that is directly triggered by invaded pathogens and indirectly triggered by IFN-γ, acts as a defense by mediating intracellular microbial recognition and clearance. In addition, autophagy contributes to inflammation by facilitating an IFN-γ response and signal transduction. For immune escape, downregulated autophagy may be a strategy used by microbes.
authors.affiliation: Institute of Clinical Medicine, College of Medicine, National Cheng Kung University, 1 University Road, Tainan 701, Taiwan, ROC.
authors.forename: Yu-Ping
authors.initials: YP
authors.lastname: Chang
authors.forename: Chia-Ling
authors.initials: CL
authors.lastname: Chen
authors.forename: Su-O
authors.initials: SO
authors.lastname: Chen
authors.forename: Yee-Shin
authors.initials: YS
authors.lastname: Lin
authors.forename: Cheng-Chieh
authors.initials: CC
authors.lastname: Tsai
authors.forename: Wei-Ching
authors.initials: WC
authors.lastname: Huang
authors.forename: Chi-Yun
authors.initials: CY
authors.lastname: Wang
authors.forename: Chia-Yuan
authors.initials: CY
authors.lastname: Hsieh
authors.forename: Pui-Ching
authors.initials: PC
authors.lastname: Choi
authors.forename: Chiou-Feng
authors.initials: CF
authors.lastname: Lin
mesh_terms: D001343:Autophagy / Q000276:immunology*; D003141:Communicable Diseases / Q000276:immunology; D057131:Immune Evasion; D007249:Inflammation / Q000276:immunology; D007371:Interferon-gamma / Q000276:immunology*; D015398:Signal Transduction
chemical_list: D007371:Interferon-gamma