title: Palladium-assisted multicomponent cyclization of aromatic aldehydes, arylamines and terminal olefins under molecular oxygen: an assembly of 1,4-dihydropyridines.
abstract: The palladium-assisted one-pot three-component reactions of aldehydes, amines and olefins proceeded smoothly to give 2,6-unsubstituted 1,4-dihydropyridines (1,4-DHPs) using molecular oxygen as a sole oxidant. It also provides efficient Pd-catalyzed aerobic oxidation access to the anti-Markovnikov oxidative amination products of olefins from primary aromatic amines and alkenes. The method is atom-efficient, using cheap and easily available starting materials and an environmentally benign oxidant.
authors.affiliation: School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou, 510640, P. R. China. jianghf@scut.edu.cn
authors.forename: Huanfeng
authors.initials: H
authors.lastname: Jiang
authors.forename: Xiaochen
authors.initials: X
authors.lastname: Ji
authors.forename: Yibiao
authors.initials: Y
authors.lastname: Li
authors.forename: Zhengwang
authors.initials: Z
authors.lastname: Chen
authors.forename: Azhong
authors.initials: A
authors.lastname: Wang