title: Genetic variation at 5 new autosomal short tandem repeat markers (D10S1248, D22S1045, D2S441, D1S1656, D12S391) in a population-based sample from Maghreb region.
abstract: OBJECTIVE
  To investigate allele distribution and genetic parameters of a population-based sample from Maghreb region.
  
  
  METHODS
  Allele frequencies for 5 new autosomal short tandem repeat (STR) markers (D10S1248, D22S1045, D2S441, D1S1656, and D12S391) and several forensic parameters were determined for 95 unrelated individuals.
  
  
  RESULTS
  The combined power of discrimination and power of exclusion for the 5 loci were high (0.9999991 and 0.9954757, respectively). Allele frequencies were compared with previously published population data. Significant differences were found between Maghreb population and all other populations at the locus D2S441. Also, significant differences were found between the Maghreb and the African American population at the D22S1045, D1S1656, and D12S391 loci, between Maghreb and Caucasian population at the D1S1656 locus, and between Maghreb and Hispanic population at the D22S1045 locus.
  
  
  CONCLUSIONS
  Typing of the 5 new STR loci may provide a useful addition to the previously established sets of autosomal STRs.
authors.affiliation: Department of Forensic Medicine, University of Brescia, Brescia, Italy.
authors.forename: Venusia
authors.initials: V
authors.lastname: Cortellini
authors.forename: Nicoletta
authors.initials: N
authors.lastname: Cerri
authors.forename: Andrea
authors.initials: A
authors.lastname: Verzeletti
mesh_terms: D000483:Alleles; D030541:Databases, Genetic; D053803:Forensic Genetics / Q000295:instrumentation / Q000379:methods*; D005784:Gene Amplification; D005787:Gene Frequency; D005819:Genetic Markers / Q000235:genetics*; D014644:Genetic Variation / Q000235:genetics*; D005828:Genetics, Population; D006801:Humans; D007558:Italy; D018895:Microsatellite Repeats / Q000235:genetics*; D044465:White People / Q000235:genetics*
chemical_list: D005819:Genetic Markers