title: Acute motor axonal neuropathy cases in Van region.
abstract: Acute motor axonal neuropathy (AMAN) is a form of Guillain Barré Syndrome (GBS) seen in summer months in Northern China to cause epidemics. This form of the disease, which is also sporadically observed in other countries, constitutes less than 5% of GBS in Western countries. It usually develops with motor findings. No sensory findings are observed. In some of the cases, the severe impairments in tissues improve however slowly and inadequately. In the motor conduction studies of cases with AMAN, motor action potential values are lowered. On needle electromyography (EMG), motor unit potential (MUP) activity is diminished with spontaneous denervation findings. Investigations were conducted on nerve conduction of patients with GBS aged from 1 to 77 years. AMAN was detected in 25 of these patients. In our investigation, AMAN as a GBS variant was detected in 39.7% of the patients. The conduction velocities of motor nerves were in normal ranges whereas combined muscle action potentials were significantly lower. No F response could be obtained. Although AMAN is a rare variant of GBS and shows different clinical courses, it has been brought under intense scrutiny since there is high prevalance of acute inflammatory neuropathies in our region (Tab. 1, Ref. 7).
authors.affiliation: Department of Neurology, Yuzuncu Yýl University of Medical Faculty in Van, Turkey. refahsayin@yyu.edu.tr
authors.forename: R
authors.initials: R
authors.lastname: Sayin
authors.forename: T
authors.initials: T
authors.lastname: Tombul
authors.forename: T C
authors.initials: TC
authors.lastname: Gulec
authors.forename: O
authors.initials: O
authors.lastname: Anlar
authors.forename: S
authors.initials: S
authors.lastname: Akbayram
authors.forename: H
authors.initials: H
authors.lastname: Caksen
mesh_terms: D000200:Action Potentials; D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D004576:Electromyography; D005260:Female; D020275:Guillain-Barre Syndrome / Q000175:diagnosis* / Q000453:epidemiology / Q000503:physiopathology; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D009431:Neural Conduction; D014421:Turkey / Q000453:epidemiology; D055815:Young Adult