title: Leydig cell tumour of the ovary localised with positron emission tomography/computed tomography.
abstract: Androgen-producing ovarian tumours can lead to assessment difficulties because of their small size. We present a case of virilising steroid cell ovarian tumour in a 41-year-old woman localised with Fluorine-18-Deoxyglucose Positron Emission Tomography/Computed Tomography ((18)FDG-PET/CT). Although the biochemical evaluation pointed to an ovarian source of androgen, diagnostic attempts to localise the source of hyperandrogenism with transvaginal ultrasound (US), and magnetic resonance imaging (MRI) of pelvis failed. Additional evaluation with (18)FDG-PET/CT showed an increased uptake in the right ovary. A laparoscopic right oophorectomy was performed and histopathology examination revealed a 1.2-cm Leydig cell tumour. The patient showed regression of clinical signs.
authors.affiliation: PET/CT Department, 'Hygeia' Hospital, Athens, Greece.
authors.forename: Vasileios
authors.initials: V
authors.lastname: Prassopoulos
authors.forename: Fotios
authors.initials: F
authors.lastname: Laspas
authors.forename: Fani
authors.initials: F
authors.lastname: Vlachou
authors.forename: Roxani
authors.initials: R
authors.lastname: Efthimiadou
authors.forename: Lida
authors.initials: L
authors.lastname: Gogou
authors.forename: John
authors.initials: J
authors.lastname: Andreou
mesh_terms: D000328:Adult; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D007984:Leydig Cell Tumor / Q000000981:diagnostic imaging* / Q000473:pathology / Q000503:physiopathology / Q000601:surgery; D064847:Multimodal Imaging; D010051:Ovarian Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000503:physiopathology / Q000601:surgery; D010052:Ovariectomy; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D047368:Tumor Burden; D014770:Virilism / Q000209:etiology
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18