title: Electrodeposition on nanofibrous polymer scaffolds: Rapid mineralization, tunable calcium phosphate composition and topography.
abstract: We developed a straightforward, fast, and versatile technique to fabricate mineralized nanofibrous polymer scaffolds for bone regeneration in this work. Nanofibrous poly(l-lactic acid) scaffolds were fabricated using both electrospinning and phase separation techniques. An electrodeposition process was designed to deposit calcium phosphate on the nanofibrous scaffolds. Such scaffolds contain a high quality mineral coating on the fiber surface with tunable surface topography and chemical composition by varying the processing parameters, which can mimic the composition and structure of natural bone extracellular matrix and provide a more biocompatible interface for bone regeneration.
authors.affiliation: Department of Biologic and Materials Sciences, University of Michigan, Ann Arbor, MI, 48109 (USA).
authors.forename: Chuanglong
authors.initials: C
authors.lastname: He
authors.forename: Guiyong
authors.initials: G
authors.lastname: Xiao
authors.forename: Xiaobing
authors.initials: X
authors.lastname: Jin
authors.forename: Chenghui
authors.initials: C
authors.lastname: Sun
authors.forename: Peter X
authors.initials: PX
authors.lastname: Ma