title: [Level of receptor complex molecule expression of human blood T-lymphocytes under conditions of their UV-irradiation].
abstract: The influence of a wide range of doses of UV-light (240-390 nm) on the expression level of receptor complex molecules (CD3, CD4, CD8 markers) on the membrane surface of human blood T-lymphocytes has been studied using flow cytometry and enzyme linked immunosorbent assay. UV-light at small and medium doses (15 1, 453 and 906 J/m2) has been established to have a unidirectional (activating) effect on the expression level of receptor complex molecules, and at a high dose of 1359 J/m2 it can either increase (CD4 and CD8 markers) or reduce (CD3 complexes) the quantity of the analyzed molecules on the membrane surface of T-lymphocytes.
authors.forename: V G
authors.initials: VG
authors.lastname: Artiukhov
authors.forename: O V
authors.initials: OV
authors.lastname: Putintseva
authors.forename: V A
authors.initials: VA
authors.lastname: Vdovina
authors.forename: I A
authors.initials: IA
authors.lastname: Koltakov
authors.forename: M V
authors.initials: MV
authors.lastname: Pashkov
authors.forename: D V
authors.initials: DV
authors.lastname: Vasilenko
mesh_terms: D017252:CD3 Complex / Q000096:biosynthesis*; D015704:CD4 Antigens / Q000096:biosynthesis*; D016827:CD8 Antigens / Q000096:biosynthesis*; D002462:Cell Membrane / Q000276:immunology / Q000378:metabolism / Q000528:radiation effects; D002478:Cells, Cultured; D004307:Dose-Response Relationship, Radiation; D005434:Flow Cytometry; D006801:Humans; D007124:Immunoenzyme Techniques; D011948:Receptors, Antigen, T-Cell / Q000096:biosynthesis*; D013601:T-Lymphocytes / Q000276:immunology / Q000378:metabolism / Q000528:radiation effects*; D014466:Ultraviolet Rays
chemical_list: D017252:CD3 Complex; D015704:CD4 Antigens; D016827:CD8 Antigens; D011948:Receptors, Antigen, T-Cell