title: Sodium oxybate-induced sleep driving and sleep-related eating disorder.
abstract: Hypnosedative-induced complex behaviors have gained increased attention in recent years as a potential complication of benzodiazepines and benzodiazepine-receptor agonist use. Sodium oxybate (SO), the sodium salt of γ-hydroxybutyrate, an inhibitory neurotransmitter, has been associated with dose-dependent rates of somnambulism; however, there is limited information about complex motor behaviors with SO. We describe a patient with narcolepsy-cataplexy who experienced one episode of sleep-driving and at least two sleep-related eating episodes with therapeutic doses of SO.
authors.affiliation: Department of Neurology, Sleep Medicine Division, University of Miami Miller School of Medicine, Miami, FL, USA. dwallace@med.miami.edu
authors.forename: Douglas McKay
authors.initials: DM
authors.lastname: Wallace
authors.forename: Tanisha
authors.initials: T
authors.lastname: Maze
authors.forename: Shirin
authors.initials: S
authors.lastname: Shafazand
mesh_terms: D000759:Adjuvants, Anesthesia / Q000009:adverse effects* / Q000627:therapeutic use; D000328:Adult; D001334:Automobile Driving; D001068:Feeding and Eating Disorders / Q000139:chemically induced*; D006801:Humans; D008297:Male; D009290:Narcolepsy / Q000188:drug therapy*; D020447:Parasomnias / Q000139:chemically induced*; D012893:Sleep Wake Disorders / Q000139:chemically induced; D012978:Sodium Oxybate / Q000009:adverse effects* / Q000627:therapeutic use
chemical_list: D000759:Adjuvants, Anesthesia; D012978:Sodium Oxybate