title: Local adjuvants in surgical management of bone metastases.
abstract: Curettage is one of the most common method for surgical treatment of bone metastasis. Local adjuvant improve most commonly used for improving the effect of curettage in local cancer surgery may exerted their effects either chemically either physically; in Orthopedic Oncology the most common are phenol, liquid nitrogen, laser, and cement. This article reviewed the main characteristics of the most common chemical and physical agents used in bone oncology, emphasizing the toxic effects of some of them, especially phenol and liquid nitrogen.
authors.affiliation: Orthopedic Oncology University La Sapienza, Rome, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Piccioli
authors.forename: A
authors.initials: A
authors.lastname: Ventura
authors.forename: G
authors.initials: G
authors.lastname: Maccauro
authors.forename: M S
authors.initials: MS
authors.lastname: Spinelli
authors.forename: V
authors.initials: V
authors.lastname: Del Bravo
authors.forename: M A
authors.initials: MA
authors.lastname: Rosa
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000008:administration & dosage* / Q000627:therapeutic use*; D001843:Bone Cements; D001859:Bone Neoplasms / Q000556:secondary* / Q000601:surgery*; D017024:Chemotherapy, Adjuvant / Q000379:methods*; D003452:Cryosurgery; D004564:Electrocoagulation; D018212:Giant Cell Tumor of Bone / Q000556:secondary* / Q000601:surgery*; D006801:Humans; D015552:Injections, Intralesional; D053685:Laser Therapy; D019800:Phenol / Q000627:therapeutic use; D019904:Polymethyl Methacrylate
chemical_list: D000970:Antineoplastic Agents; D001843:Bone Cements; D019800:Phenol; D019904:Polymethyl Methacrylate