title: Microbial metabolism and biotechnological production of D-allose.
abstract: D-allose has attracted a great deal of attention in recent years due to its many pharmaceutical activities, which include anti-cancer, anti-tumor, anti-inflammatory, anti-oxidative, anti-hypertensive, cryoprotective, and immunosuppressant activities. D-allose has been produced from D-psicose using D-allose-producing enzymes, including L-rhamnose isomerase, ribose-5-phosphate isomerase, and galactose-6-phosphate isomerase. In this article, the properties, applications, and metabolism of D-allose are described, and the biochemical properties of D-allose-producing enzymes and their D-allose production are reviewed and compared. Moreover, several methods for effective D-allose production are suggested herein.
authors.affiliation: Department of Bioscience and Biotechnology, Konkuk University, 1 Hwayang-Dong Gwangjin-Gu, Seoul 143-701, South Korea.
authors.forename: Yu-Ri
authors.initials: YR
authors.lastname: Lim
authors.forename: Deok-Kun
authors.initials: DK
authors.lastname: Oh
mesh_terms: D019747:Aldose-Ketose Isomerases / Q000378:metabolism; D001419:Bacteria / Q000201:enzymology* / Q000378:metabolism; D001709:Biotechnology / Q000379:methods*; D005632:Fructose / Q000378:metabolism*; D005947:Glucose / Q000096:biosynthesis*
chemical_list: C003243:psicose; D005632:Fructose; C002055:allose; D019747:Aldose-Ketose Isomerases; C023084:galactose-6-phosphate isomerase; C062878:L-rhamnose isomerase; C022548:ribosephosphate isomerase; D005947:Glucose