title: Prenatal assessment and management of sacrococcygeal teratoma.
abstract: Sacrococcygeal teratoma (SCT) is one of the most common tumors in newborns with a birth prevalence of up to 1 in 21,700 births. Routine fetal anomaly screening programs allow for prenatal diagnosis in many cases. Fetal ultrasound with Doppler evaluation and more recently magnetic resonance imaging may be used to document the extent of the tumor as well as identifying the population at risk for serious fetal complications. Rapidly growing SCT and highly vascularized tumors are more likely to have hemodynamic repercussions. Fetal hydrops is usually considered as a poor prognostic marker and a potential indicator for fetal intervention. Newborns with SCT require stabilization prior to early surgical resection. In case of malignancy additional chemotherapy may be required. SCT may result in significant morbidity, either directly or as a consequence of surgical therapy. Careful postnatal follow-up is required for timely identification and treatment of complications as well as recurrence. This paper aims to review the perinatal management of this condition.
authors.affiliation: Department of Woman and Child, Division Woman, Fetal Medicine Unit, University Hospital Gasthuisberg Leuven, Leuven, Belgium.
authors.forename: Leonardo
authors.initials: L
authors.lastname: Gucciardo
authors.forename: Anne
authors.initials: A
authors.lastname: Uyttebroek
authors.forename: Ivo
authors.initials: I
authors.lastname: De Wever
authors.forename: Marleen
authors.initials: M
authors.lastname: Renard
authors.forename: Filip
authors.initials: F
authors.lastname: Claus
authors.forename: Roland
authors.initials: R
authors.lastname: Devlieger
authors.forename: Liesbeth
authors.initials: L
authors.lastname: Lewi
authors.forename: Luc
authors.initials: L
authors.lastname: De Catte
authors.forename: Jan
authors.initials: J
authors.lastname: Deprest
mesh_terms: D001859:Bone Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy*; D005260:Female; D046128:Fetal Therapies / Q000379:methods; D006801:Humans; D011247:Pregnancy; D011295:Prenatal Care / Q000379:methods; D011296:Prenatal Diagnosis / Q000379:methods*; D012445:Sacrococcygeal Region / Q000473:pathology; D013724:Teratoma / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy*; D016896:Treatment Outcome