title: Ability of commonly used prediction equations to predict resting energy expenditure in children with inflammatory bowel disease.
abstract: BACKGROUND
  Paediatric onset inflammatory bowel disease (IBD) may cause alterations in energy requirements and invalidate the use of standard prediction equations. Our aim was to evaluate four commonly used prediction equations for resting energy expenditure (REE) in children with IBD.
  
  
  METHODS
  Sixty-three children had repeated measurements of REE as part of a longitudinal research study yielding a total of 243 measurements. These were compared with predicted REE from Schofield, Oxford, FAO/WHO/UNU, and Harris-Benedict equations using the Bland-Altman method.
  
  
  RESULTS
  Mean (±SD) age of the patients was 14.2 (2.4) years. Mean measured REE was 1566 (336) kcal per day compared with 1491 (236), 1441 (255), 1481 (232), and 1435 (212) kcal per day calculated from Schofield, Oxford, FAO/WHO/UNU, and Harris-Benedict, respectively. While the Schofield equation demonstrated the least difference between measured and predicted REE, it, along with the other equations tested, did not perform uniformly across all subjects, indicating greater errors at either end of the spectrum of energy expenditure. Smaller differences were found for all prediction equations for Crohn's disease compared with ulcerative colitis.
  
  
  CONCLUSIONS
  Of the commonly used equations, the equation of Schofield should be used in pediatric patients with IBD when measured values are not able to be obtained.
authors.affiliation: The University of Queensland, Children's Nutrition Research Centre, Royal Children's Hospital, Herston, QLD 4029, Australia. rj.hill@uq.edu.au
authors.forename: Rebecca J
authors.initials: RJ
authors.lastname: Hill
authors.forename: Peter J
authors.initials: PJ
authors.lastname: Lewindon
authors.forename: Geoffrey D
authors.initials: GD
authors.lastname: Withers
authors.forename: Frances L
authors.initials: FL
authors.lastname: Connor
authors.forename: Looi C
authors.initials: LC
authors.lastname: Ee
authors.forename: Geoffrey J
authors.initials: GJ
authors.lastname: Cleghorn
authors.forename: Peter S W
authors.initials: PS
authors.lastname: Davies
mesh_terms: D000293:Adolescent; D001481:Basal Metabolism / Q000502:physiology*; D002153:Calorimetry, Indirect; D002648:Child; D003093:Colitis, Ulcerative / Q000150:complications* / Q000523:psychology*; D003424:Crohn Disease / Q000150:complications* / Q000523:psychology*; D002149:Energy Intake; D004734:Energy Metabolism / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D008433:Mathematics; D015596:Nutrition Assessment; D011237:Predictive Value of Tests