title: Tetrahedron-structured DNA and functional oligonucleotide for construction of an electrochemical DNA-based biosensor.
abstract: Tetrahedron-structured DNA (ts-DNA) in combination with a functionalized oligonucleotide was used to develop a "turn-on" biosensor for Hg(2+) ions. The ts-DNA provided an improved sensitivity and was used to block the active sites.
authors.affiliation: Research Center for Analytical Sciences, College of Chemistry, Nankai University, Tianjin, 300071, PR China.
authors.forename: Nan-Nan
authors.initials: NN
authors.lastname: Bu
authors.forename: Chun-Xia
authors.initials: CX
authors.lastname: Tang
authors.forename: Xi-Wen
authors.initials: XW
authors.lastname: He
authors.forename: Xue-Bo
authors.initials: XB
authors.lastname: Yin
mesh_terms: D015374:Biosensing Techniques / Q000379:methods*; D004247:DNA / Q000737:chemistry*; D004563:Electrochemistry / Q000379:methods*; D008628:Mercury / Q000032:analysis*; D009841:Oligonucleotides / Q000737:chemistry*; D045483:Rivers / Q000737:chemistry; D012680:Sensitivity and Specificity; D014867:Water / Q000032:analysis; D014874:Water Pollutants, Chemical / Q000032:analysis*
chemical_list: D009841:Oligonucleotides; D014874:Water Pollutants, Chemical; D014867:Water; D004247:DNA; D008628:Mercury