title: Long-term survival of a patient after resection of a gastrointestinal stromal tumor arising from the pancreas.
abstract: BACKGROUND
  Gastrointestinal stromal tumors (GISTs) may arise in any part of the gastrointestinal tract; extra-gastrointestinal locations are extremely rare. Only a few cases of extragastrointestinal stromal tumor arising from the pancreas were reported. None of the reports described a long-term follow-up of the patients.
  
  
  METHODS
  This report describes an interesting and unusual case of GIST arising from the pancreas.
  
  
  RESULTS
  A 74-year-old female presented with a palpable abdominal mass. CT scan showed a large mass 11 x 8 x 4 cm originating from the tail of the pancreas. Percutaneous biopsy revealed a GIST predominantly with spindle cells, but some parts also contained epitheloid cells. The patient was treated by distal pancreatic resection with splenectomy. Immunohistochemistry of the tumor showed a staining pattern characteristic of GIST. The patient has achieved a long-term survival of five years and six months without any sign of recurrence of the disease.
  
  
  CONCLUSIONS
  This is the first reported case of an extra-gastrointestinal stromal tumor arising from the pancreas treated surgically, with a long-term survival.
authors.affiliation: Department of Surgery, Faculty of Medicine and University Hospital Hradec Králové, 500 05 Hradec Králové, Czech Republic. filip.cecka@seznam.cz
authors.forename: Filip
authors.initials: F
authors.lastname: Čečka
authors.forename: Bohumil
authors.initials: B
authors.lastname: Jon
authors.forename: Alexander
authors.initials: A
authors.lastname: Ferko
authors.forename: Zdeněk
authors.initials: Z
authors.lastname: Šubrt
authors.forename: Dimitar H
authors.initials: DH
authors.lastname: Nikolov
authors.forename: Věra
authors.initials: V
authors.lastname: Tyčová
mesh_terms: D000368:Aged; D001706:Biopsy; D005260:Female; D046152:Gastrointestinal Stromal Tumors / Q000473:pathology / Q000601:surgery*; D006801:Humans; D007150:Immunohistochemistry; D010180:Pancreatectomy; D010190:Pancreatic Neoplasms / Q000473:pathology / Q000601:surgery*; D013156:Splenectomy; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome