title: Early and long-term outcome of surgery for cardiac myxoma: experience of a single cardiac surgical centre.
abstract: BACKGROUND
  Outcome after surgery for cardiac myxoma is very good, although due to relatively low prevalence in general population there are only a few reports with long-term follow-up that involved large number of patients.
  
  
  OBJECTIVE
  To evaluate short- and long-term outcome after myxoma removal in a single cardiac surgical centre.
  
  
  METHODS
  The study involved 64 patients (42 women and 22 men) at the age ranging from 21 to 79 (mean 54.1 ± 18.8) years who were treated between 1981-2009 in our institution. All patients were operated on from median sternotomy and cardiopulmonary bypass. Additionally, in 6 (9.4%) patients coronary artery bypass grafting was performed (1 to 3 grafts were implanted) and in other 2 (3.1%) ostium secundum atrial septal defect was closed. Patient survival and complications rate were assessed using the Kaplan-Meier curves. Moreover, functional status at the last follow-up examination was evaluated.
  
  
  RESULTS
  Two patients died in the perioperative period (in-hospital mortality 3.1%) and 4 during follow-up ranging from 5 to 320 months (median 81 months, cumulated follow-up period 5376 patient-months). Four other patients were lost from follow-up. One-year survival probability was 0.95 ± 0.03, 5-year - 0.88 ± 0.04 and 10-year - 0.84 ± 0.06. Estimated 10-year freedom from cardiac complications was 0.72 ± 0.08, hospital readmission 0.80 ± 0.07 and cardiac surgical reintervention 0.96 ± 0.03. None of the patients had tumour recurrence. At the last follow-up examination, 90.7% of patients were in functional NYHA classes I or II.
  
  
  CONCLUSIONS
  Surgery for cardiac myxoma is associated with low long-term mortality and morbidity. Functional status following operation improved significantly after surgery.
authors.affiliation: Department of Cardiac Surgery, Poznan University of Medical Sciences, Poznan, Poland.
authors.forename: Bartłomiej
authors.initials: B
authors.lastname: Perek
authors.forename: Marcin
authors.initials: M
authors.lastname: Misterski
authors.forename: Sebastian
authors.initials: S
authors.lastname: Stefaniak
authors.forename: Marcin
authors.initials: M
authors.lastname: Ligowski
authors.forename: Mateusz
authors.initials: M
authors.lastname: Puślecki
authors.forename: Marek
authors.initials: M
authors.lastname: Jemielity
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006338:Heart Neoplasms / Q000401:mortality* / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009232:Myxoma / Q000401:mortality* / Q000601:surgery*; D016896:Treatment Outcome