title: Ultra high molecular weight polyethylene is cytotoxic and causes oxidative stress, even when modified.
authors.affiliation: Department of Genetics, Biology and Biochemistry, University of Turin, Italy.
authors.forename: E
authors.initials: E
authors.lastname: Gazzano
authors.forename: P
authors.initials: P
authors.lastname: Bracco
authors.forename: A
authors.initials: A
authors.lastname: Bistolfi
authors.forename: E
authors.initials: E
authors.lastname: Aldieri
authors.forename: D
authors.initials: D
authors.lastname: Ghigo
authors.forename: M
authors.initials: M
authors.lastname: Boffano
authors.forename: L
authors.initials: L
authors.lastname: Costa
authors.forename: E
authors.initials: E
authors.lastname: Brach Del Prever
mesh_terms: D000818:Animals; D001672:Biocompatible Materials / Q000737:chemistry* / Q000633:toxicity*; D002460:Cell Line; D019070:Cell Lineage; D002470:Cell Survival / Q000187:drug effects; D003432:Cross-Linking Reagents; D006801:Humans; D007770:L-Lactate Dehydrogenase / Q000378:metabolism; D008264:Macrophages / Q000187:drug effects; D051379:Mice; D008970:Molecular Weight; D009000:Monocytes / Q000187:drug effects; D009569:Nitric Oxide / Q000378:metabolism; D010010:Osteoclasts / Q000187:drug effects; D010084:Oxidation-Reduction; D018384:Oxidative Stress / Q000187:drug effects*; D011095:Polyethylenes / Q000737:chemistry* / Q000633:toxicity*; D017382:Reactive Oxygen Species / Q000378:metabolism; D017550:Spectroscopy, Fourier Transform Infrared; D014810:Vitamin E / Q000737:chemistry
chemical_list: D001672:Biocompatible Materials; D003432:Cross-Linking Reagents; D011095:Polyethylenes; D017382:Reactive Oxygen Species; C111601:ultra-high molecular weight polyethylene; D014810:Vitamin E; D009569:Nitric Oxide; D007770:L-Lactate Dehydrogenase