title: [EYECUBE as 3D multimedia imaging in macular diagnostics].
abstract: BACKGROUND
  In the new generation of EYECUBE devices, the angiography image and the OCT are included in a 3D illustration as an integration. Other diagnostic procedures such as autofluorescence and ICG can also be correlated to the OCT. The aim was to precisely classify various two-dimensional findings in relation to each other.
  
  
  METHODS
  The new generation of OCT devices enables imaging with a low incidence of motion artefacts with very good fundus image quality - and with that, permits a largely automatic classification. The feature enabling the integration of the EYECUBE was further developed with new software, so that not only the topographic image (red-free, autofluorescence) can be correlated to the Cirrus OCT, but also all other findings gathered within the same time frame can be correlated to each other. These were brightened and projected onto the cube surface in a defined interval. The imaging procedures can be selected in a menu toolbar. Topographic volumetry OCT images can be overlayed. The practical application of the new method was tested on patients with macular disorders.
  
  
  RESULTS
  By lightening up the results from various diagnostic procedures, it is possible of late to directly compare pathologies to each other and to the OCT results. In all patients (n = 45 eyes) with good single-image quality, the automated integration into the EYECUBE was possible (to a great extent). The application is not dependent on a certain type of device used in the procedures performed.
  
  
  CONCLUSIONS
  The increasing level of precision in imaging procedures and the handling of large data volumes has led to the possibility of examining each macular diagnostics procedure from the comparative perspective: imaging (photo) with perfusion (FLA, ICG) and morphology (OCT). The exclusion of motion artefacts and the reliable scan position in the course of the imaging process increases the informative value of OCT.
authors.affiliation: Augenklinik, Universitäts-Augenklinik, Hamburg. hassenstein@uke.uni-hamburg.de
authors.forename: Andrea
authors.initials: A
authors.lastname: Hassenstein
authors.forename: F
authors.initials: F
authors.lastname: Scholz
authors.forename: G
authors.initials: G
authors.lastname: Richard
mesh_terms: D000328:Adult; D000792:Angiography / Q000295:instrumentation*; D004867:Equipment Design; D019544:Equipment Failure Analysis; D005260:Female; D006801:Humans; D021621:Imaging, Three-Dimensional / Q000295:instrumentation*; D008268:Macular Degeneration / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D042261:Retinoscopes; D012680:Sensitivity and Specificity; D013382:Subtraction Technique / Q000295:instrumentation*; D041623:Tomography, Optical Coherence / Q000295:instrumentation*; D055815:Young Adult