title: Antibiotics for gram-positive bacterial infection: vancomycin, teicoplanin, quinupristin/dalfopristin, oxazolidinones, daptomycin, telavancin, and ceftaroline.
abstract: An overview of the mechanism of action, dosing, clinical indications, and toxicities of the glycopeptide vancomycin is provided. The emerging gram-positive bacterial resistance to antimicrobials and its mechanisms are reviewed. Strategies to control this emergence of resistance are expected to be proposed. Newer antimicrobial agents that have activity against vancomycin-resistant organisms are now available and play a critical role in the treatment of life-threatening infections.
authors.affiliation: University of Connecticut School of Pharmacy, 69 North Eagleville Road Unit 3092, Storrs, CT 06269, USA.
authors.forename: Michael D
authors.initials: MD
authors.lastname: Nailor
authors.forename: Jack D
authors.initials: JD
authors.lastname: Sobel