title: The essential β-barrel assembly machinery complex components BamD and BamA are required for autotransporter biogenesis.
abstract: Autotransporter biogenesis is dependent upon BamA, a central component of the β-barrel assembly machinery (BAM) complex. In this report, we detail the role of the other BAM components (BamB-E). We identify the importance of BamD in autotransporter biogenesis and show that BamB, BamC, and BamE are not required.
authors.affiliation: School of Immunity and Infection, University of Birmingham, Birmingham B15 2TT, United Kingdom.
authors.forename: Amanda E
authors.initials: AE
authors.lastname: Rossiter
authors.forename: Denisse L
authors.initials: DL
authors.lastname: Leyton
authors.forename: Karina
authors.initials: K
authors.lastname: Tveen-Jensen
authors.forename: Douglas F
authors.initials: DF
authors.lastname: Browning
authors.forename: Yanina
authors.initials: Y
authors.lastname: Sevastsyanovich
authors.forename: Timothy J
authors.initials: TJ
authors.lastname: Knowles
authors.forename: Katie B
authors.initials: KB
authors.lastname: Nichols
authors.forename: Adam F
authors.initials: AF
authors.lastname: Cunningham
authors.forename: Michael
authors.initials: M
authors.lastname: Overduin
authors.forename: Mark A
authors.initials: MA
authors.lastname: Schembri
authors.forename: Ian R
authors.initials: IR
authors.lastname: Henderson
mesh_terms: D001425:Bacterial Outer Membrane Proteins / Q000235:genetics / Q000378:metabolism*; D001692:Biological Transport; D002352:Carrier Proteins; D004926:Escherichia coli / Q000235:genetics / Q000378:metabolism*; D029968:Escherichia coli Proteins / Q000235:genetics / Q000378:metabolism*; D015964:Gene Expression Regulation, Bacterial / Q000502:physiology*; D058635:Lipid-Linked Proteins / Q000235:genetics / Q000378:metabolism; D011487:Protein Conformation
chemical_list: D001425:Bacterial Outer Membrane Proteins; C503914:BamA protein, E coli; C557407:BamB protein, E coli; C556681:BamC protein, E coli; C513739:BamD protein, E coli; C523551:BamE protein, E coli; D002352:Carrier Proteins; D029968:Escherichia coli Proteins; D058635:Lipid-Linked Proteins