title: The 'T-cell-ness' of NK cells: unexpected similarities between NK cells and T cells.
abstract: NK cells are considered as prototypical innate immune cells. However, recent discoveries have tended to refine the dogmatic concepts of innate and adaptive immunity. In many ways, NK cells are highly related to T cells and represent the closest innate immune cell lineage to adaptive immune cell populations. Here, we review the relationships between NK cells and T cells and discuss the recently described cell-intrinsic-adaptive features of NK cells.
authors.affiliation: Centre d'Immunologie de Marseille-Luminy, Université de la Méditerranée, Campus de Luminy case, France.
authors.forename: Emilie
authors.initials: E
authors.lastname: Narni-Mancinelli
authors.forename: Eric
authors.initials: E
authors.lastname: Vivier
authors.forename: Yann M
authors.initials: YM
authors.lastname: Kerdiles
mesh_terms: D056704:Adaptive Immunity; D000818:Animals; D049109:Cell Proliferation; D015395:Histocompatibility Antigens Class I / Q000276:immunology; D006801:Humans; D007108:Immune Tolerance / Q000276:immunology; D007113:Immunity, Innate; D007694:Killer Cells, Natural / Q000166:cytology* / Q000276:immunology*; D013601:T-Lymphocytes / Q000166:cytology* / Q000276:immunology*
chemical_list: D015395:Histocompatibility Antigens Class I