title: Optic neuropathy as a presenting feature of systemic lupus erythematosus: two case reports and literature review.
abstract: Systemic lupus erythematosus (SLE) may affect the eyes and/or visual system in up to a third of patients; however, optic nerve involvement has been rarely reported. SLE presenting as optic neuropathy is exceptional. We report two new cases of optic neuropathy as a presenting feature of SLE. The first patient presented with an ischemic optic neuropathy and antiphospholipid antibodies, and the second presented with optic neuritis. A literature review for previous cases of SLE presenting as optic neuropathy was performed. Early diagnosis of SLE-associated optic neuropathy is warranted and leads to a better prognosis.
authors.affiliation: Department of Internal Medicine, Hedi Chaker Hospital, Sfax, Tunisia. friguimakram@yahoo.fr
authors.forename: M
authors.initials: M
authors.lastname: Frigui
authors.forename: F
authors.initials: F
authors.lastname: Frikha
authors.forename: D
authors.initials: D
authors.lastname: Sellemi
authors.forename: F
authors.initials: F
authors.lastname: Chouayakh
authors.forename: J
authors.initials: J
authors.lastname: Feki
authors.forename: Z
authors.initials: Z
authors.lastname: Bahloul
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D017152:Antibodies, Antiphospholipid / Q000097:blood; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000175:diagnosis / Q000276:immunology; D008297:Male; D009901:Optic Nerve Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D009902:Optic Neuritis / Q000209:etiology; D018917:Optic Neuropathy, Ischemic / Q000209:etiology; D055815:Young Adult
chemical_list: D000305:Adrenal Cortex Hormones; D017152:Antibodies, Antiphospholipid