title: Persistent high incidence of tuberculosis among immigrants in a low-incidence country: impact of immigrants with early or late latency.
abstract: Spread of tuberculosis (TB) due to the immigration from some developing countries with high TB incidence to developed countries poses an increasing challenge in the global TB control. Here a simple compartmental TB model with constant immigration, early and late latency is developed in order to investigate the impact of new immigrants with latent TB on the overall TB incidence, and to compare the difference contributed by different proportions of latently-infected new immigrants with high or low risk to develop active TB shortly after arrival. The global dynamics of the system is completely classified, numerical simulations are carried out for different scenarios, and potential applications to public health policy are discussed.
authors.affiliation: Centre for Disease Modeling, Department of Mathematics and Statistics, York University, 4700 Keele Street Toronto, ON, M3J 1P3, Canada. hguo@mathstat.yorku.ca
authors.forename: Hongbin
authors.initials: H
authors.lastname: Guo
authors.forename: Jianhong
authors.initials: J
authors.lastname: Wu
mesh_terms: D002170:Canada / Q000453:epidemiology; D003198:Computer Simulation; D004196:Disease Outbreaks / Q000706:statistics & numerical data*; D004641:Emigration and Immigration / Q000706:statistics & numerical data*; D006801:Humans; D015994:Incidence; D015233:Models, Statistical; D013997:Time Factors; D014376:Tuberculosis / Q000453:epidemiology*