title: Democracy derived? New trajectories in pluripotent stem cell research.
abstract: How has the development of human induced pluripotent stem cells (hiPSCs) modified the trajectory of stem cell research? Here, coauthorship networks of stem cell research articles and analysis of cell lines used in stem cell research indicate that hiPSCs are not replacing human embryonic stem cells, but instead, the two cell types are complementary, interdependent research tools. Thus, we conclude that a ban on funding for embryonic stem cell research could have unexpected negative ramifications on the nascent field of hiPSCs.
authors.affiliation: Stanford University Center for Biomedical Ethics Program on Stem Cells and Society, Stanford University, Stanford, CA 94305-5417, USA. cscott@stanford.edu
authors.forename: Christopher Thomas
authors.initials: CT
authors.lastname: Scott
authors.forename: Jennifer B
authors.initials: JB
authors.lastname: McCormick
authors.forename: Mindy C
authors.initials: MC
authors.lastname: DeRouen
authors.forename: Jason
authors.initials: J
authors.lastname: Owen-Smith
mesh_terms: D002460:Cell Line; D065150:Cellular Reprogramming; D053595:Embryonic Stem Cells / Q000166:cytology*; D006801:Humans; D057026:Induced Pluripotent Stem Cells / Q000166:cytology*; D010506:Periodicals as Topic; D039904:Pluripotent Stem Cells / Q000166:cytology*; D057905:Stem Cell Research / Q000331:legislation & jurisprudence*