title: Successful pregnancy after simultaneous pancreas-kidney transplantation from a brain-dead donor: the first case report in Japan.
abstract: Simultaneous pancreas-kidney transplantation is a revolutionary medical procedure to cure diabetes mellitus and its complications in one step. For women with type 1 diabetes mellitus and end-stage renal disease, this procedure not only treats their disease but may also allow them to have children. Worldwide, 77 pregnancies from 43 pancreas-kidney recipients have been reported. Here, we present the first case report of successful pregnancy after simultaneous pancreas-kidney transplantation from a brain-dead donor in Japan. She conceived spontaneously 32 months after transplantation. Her pregnancy course was favorable except for mild rejection of the grafted pancreas and development of gestational diabetes. She delivered a 2882-g healthy infant in October 2010. Pregnancy after simultaneous pancreas-kidney transplantation is discussed.
authors.affiliation: Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Osaka, Japan. skoyama@gyne.med.osaka-u.ac.jp
authors.forename: Shinsuke
authors.initials: S
authors.lastname: Koyama
authors.forename: Takuji
authors.initials: T
authors.lastname: Tomimatsu
authors.forename: Takeshi
authors.initials: T
authors.lastname: Kanagawa
authors.forename: Emiko
authors.initials: E
authors.lastname: Daimon
authors.forename: Tadashi
authors.initials: T
authors.lastname: Kimura
authors.forename: Akio
authors.initials: A
authors.lastname: Kuroda
authors.forename: Masahiro
authors.initials: M
authors.lastname: Tanemura
authors.forename: Yuichiro
authors.initials: Y
authors.lastname: Doki
authors.forename: Toshinori
authors.initials: T
authors.lastname: Ito
mesh_terms: D000328:Adult; D003928:Diabetic Nephropathies / Q000150:complications / Q000601:surgery; D005260:Female; D006801:Humans; D007564:Japan; D007676:Kidney Failure, Chronic / Q000209:etiology / Q000601:surgery; D016030:Kidney Transplantation; D016035:Pancreas Transplantation; D011247:Pregnancy; D011256:Pregnancy Outcome