title: Clinicopathological study of salivary gland tumors: an assessment of 303 patients.
abstract: Salivary gland neoplasms are remarkable for their histological diversity and several studies point to their varied occurrence in the population. Clinical aspects were histologically assessed to determine possible associations and define parameters to differentiate benign and malignant neoplasms. The case files of patients diagnosed with epithelial salivary gland tumors between 1989 and 2005 were reviewed. A majority (71%) of the 303 salivary gland tumors studied were benign and pleomorphic adenoma were found to be most common. Mean ages for patients with benign and malignant tumors were 49.2 and 58.5 years, respectively. A statistically significant difference between these tumors was observed for the following variables: mean age, tumor size and disease duration. A correlation was found between histological diagnosis and tumor consistency. The data presented here corroborate a number of previous studies and are therefore relevant in understanding the diverse characteristics exhibited by these tumors.
authors.affiliation: Centro de Ciências da Saúde, Universidade Federal do Rio Grande do Norte, Natal, Brasil. lourd@unp.br
authors.forename: Maria de Lourdes Silva de Arruda
authors.initials: Mde L
authors.lastname: Morais
authors.forename: Paulo Roberto
authors.initials: PR
authors.lastname: Azevedo
authors.forename: Cyntia Helena
authors.initials: CH
authors.lastname: Carvalho
authors.forename: Lélia
authors.initials: L
authors.lastname: Medeiros
authors.forename: Tirzah
authors.initials: T
authors.lastname: Lajus
authors.forename: Antonio de Lisboa Lopes
authors.initials: Ade L
authors.lastname: Costa
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D001938:Brazil / Q000453:epidemiology; D002648:Child; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012468:Salivary Gland Neoplasms / Q000453:epidemiology / Q000473:pathology*; D017678:Sex Distribution; D047368:Tumor Burden; D055815:Young Adult