title: Novel CUX1 missense mutation in association with 7q- at leukemic transformation of MPN.
authors.affiliation: Division of Hematology and Oncology, Cedars-Sinai Medical Center, UCLA School of Medicine, Los Angeles, California, USA. nils.thoennissen@ukmuenster.de
authors.forename: Nils H
authors.initials: NH
authors.lastname: Thoennissen
authors.forename: Terra
authors.initials: T
authors.lastname: Lasho
authors.forename: Gabriela B
authors.initials: GB
authors.lastname: Thoennissen
authors.forename: Seishi
authors.initials: S
authors.lastname: Ogawa
authors.forename: Ayalew
authors.initials: A
authors.lastname: Tefferi
authors.forename: H Phillip
authors.initials: HP
authors.lastname: Koeffler
mesh_terms: D048868:Adaptor Proteins, Signal Transducing; D033942:Adaptor Proteins, Vesicular Transport / Q000235:genetics; D002872:Chromosome Deletion; D002897:Chromosomes, Human, Pair 7 / Q000235:genetics; D020732:Cytogenetic Analysis; D056726:Genetic Association Studies; D018398:Homeodomain Proteins / Q000235:genetics*; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000150:complications / Q000235:genetics; D019656:Loss of Heterozygosity; D020125:Mutation, Missense; D009196:Myeloproliferative Disorders / Q000150:complications / Q000235:genetics*; D009687:Nuclear Proteins / Q000235:genetics*; D020411:Oligonucleotide Array Sequence Analysis; D020641:Polymorphism, Single Nucleotide; D055728:Primary Myelofibrosis / Q000150:complications / Q000235:genetics; D017434:Protein Structure, Tertiary; D012097:Repressor Proteins / Q000235:genetics*; D014157:Transcription Factors; D014170:Transformation, Genetic
chemical_list: D048868:Adaptor Proteins, Signal Transducing; D033942:Adaptor Proteins, Vesicular Transport; C080632:CUX1 protein, human; D018398:Homeodomain Proteins; D009687:Nuclear Proteins; D012097:Repressor Proteins; C107249:SH2B2 protein, human; D014157:Transcription Factors