title: Prevalence and clinical significance of pancreatic cysts associated with cysts in other organs.
abstract: OBJECTIVE
  Von Hippel-Lindau disease is associated with serous cysts in the pancreas and kidneys. In this study we determined the prevalence of pancreatic cysts occurring concurrently with other abdominal cysts and tested the hypothesis that these patients might represent a forme fruste of Von Hippel-Lindau disease and be more likely to be serous cysts.
  
  
  METHODS
  A retrospective chart review of patients undergoing endoscopic ultrasound of pancreatic cysts.
  
  
  RESULTS
  A total of 156 patients were included in the study. Eighty-five patients (54.8%) had cyst(s) in the pancreas and at least one other intra-abdominal cyst. These cysts included 24 (27.9%) serous cysts, 30 (34.9%), mucinous cysts, 6 (7%) adenocarcinoma and 25 (29.4%) unknowns. Seventy-one patients (45.2%) had isolated pancreatic cysts. These included 17 (23.9%) serous cysts, 28 (39.5%) mucinous cysts, 4 (5.6%) adenocarcinoma and 22 (31%) unknowns. The odds of serous cysts with concurrent extra-pancreatic and pancreatic cysts compared to odds of serous cysts with pancreatic cysts alone were 1.3 (95% CI: 0.6-2.9).
  
  
  CONCLUSIONS
  Pancreatic cysts are associated with cysts in other abdominal organs in 54.8% patients. The prevalence of serous cysts was not higher amongst individuals with multiple organ cysts compared to those with only pancreatic cysts.
authors.affiliation: University Texas Southwestern Medical Center, Dallas, TX, United States. deepak ag@yahoo.com
authors.forename: Deepak
authors.initials: D
authors.lastname: Agrawal
authors.forename: Santo S
authors.initials: SS
authors.lastname: Maimone
authors.forename: Richard C K
authors.initials: RC
authors.lastname: Wong
authors.forename: Gerard
authors.initials: G
authors.lastname: Isenberg
authors.forename: Ashley
authors.initials: A
authors.lastname: Faulx
authors.forename: Amitabh
authors.initials: A
authors.lastname: Chak
mesh_terms: D000230:Adenocarcinoma / Q000150:complications* / Q000473:pathology; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D018291:Cystadenoma, Mucinous / Q000150:complications* / Q000473:pathology; D005260:Female; D006801:Humans; D052177:Kidney Diseases, Cystic / Q000150:complications; D008107:Liver Diseases / Q000150:complications / Q000473:pathology; D008297:Male; D008875:Middle Aged; D010181:Pancreatic Cyst / Q000150:complications* / Q000473:pathology; D010190:Pancreatic Neoplasms / Q000150:complications* / Q000473:pathology; D012189:Retrospective Studies; D013158:Splenic Diseases / Q000150:complications / Q000473:pathology