title: Regioselective transformation of O-propargylic arylaldoximes to four-membered cyclic nitrones by copper-catalyzed skeletal rearrangement.
abstract: (E)-O-Propargylic arylaldoximes were regioselectively converted, in the presence of copper catalysts, into their corresponding four-membered cyclic nitrones in good to excellent yields. The reactions proceeded via a tandem [2,3]-rearrangement and 4π-electrocyclization of the N-allenylnitrone intermediate and involved cleavage of the carbon-oxygen bond.
authors.affiliation: Research and Analytical Center for Giant Molecules, Graduate School of Science, Tohoku University, Sendai 980-8578, Japan. itaru-n@m.tohoku.ac.jp
authors.forename: Itaru
authors.initials: I
authors.lastname: Nakamura
authors.forename: Toshiharu
authors.initials: T
authors.lastname: Araki
authors.forename: Dong
authors.initials: D
authors.lastname: Zhang
authors.forename: Yu
authors.initials: Y
authors.lastname: Kudo
authors.forename: Eunsang
authors.initials: E
authors.lastname: Kwon
authors.forename: Masahiro
authors.initials: M
authors.lastname: Terada