title: First description of demodicosis in 12 galagos (Galago senegalensis).
abstract: Twelve Galago senegalensis from the Moscow Zoo were presented with papular to nodular (2-11 mm) lesions on the pinnae, containing a white, waxy material. Microscopic examination revealed large numbers of mites consistent with the morphology of Demodex spp. mites. Nine animals were treated with ivermectin, 600 μg/kg/day topically, orally or subcutaneously for 3-10 months, while one remained untreated. All the treated animals achieved clinical remission. The control animal was still affected and died 11 months later due to pneumonia and possible eosinophilic leukaemia. No adverse effects were noted in any animals during the treatment. No animal relapsed in the 13-19 months follow-up period. To the authors' knowledge, this is the first report of demodicosis in G. senegalensis. The use of ivermectin in G. senegalensis was safe, although its effectiveness in the treatment of demodicosis needs further investigation.
authors.affiliation: Dermatology service, Veterinary Clinic Beliy Klik-M, Krasnaya Presnya 6/2, Moscow 123242, Russia. kuznetsova_es@mail.ru
authors.forename: Ekaterina
authors.initials: E
authors.lastname: Kuznetsova
authors.forename: Anastasia
authors.initials: A
authors.lastname: Vysokikh
authors.forename: Patrick
authors.initials: P
authors.lastname: Bourdeau
mesh_terms: D000818:Animals; D000836:Animals, Zoo / Q000469:parasitology*; D004305:Dose-Response Relationship, Drug; D005260:Female; D005701:Galago / Q000469:parasitology*; D007559:Ivermectin / Q000009:adverse effects / Q000627:therapeutic use*; D008297:Male; D008924:Mite Infestations / Q000188:drug therapy / Q000662:veterinary*; D008925:Mites / Q000145:classification* / Q000187:drug effects; D016896:Treatment Outcome
chemical_list: D007559:Ivermectin