title: Concurrent detection of herpes simplex and varicella-zoster viruses by polymerase chain reaction from the same anatomic location.
abstract: Herpes simplex virus (HSV) and varicella-zoster virus (VZV) may cause latent infection of the same peripheral nerve ganglia. However, there are no large studies addressing the frequency of concurrent HSV/VZV PCR positivity from the same anatomic location. In an eight-year retrospective study, we observed 1.3% dual positivity from dermal, genital, and oral mucosal sources.
authors.affiliation: Division of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA.
authors.forename: Neelam
authors.initials: N
authors.lastname: Dhiman
authors.forename: Patricia A
authors.initials: PA
authors.lastname: Wright
authors.forename: Mark J
authors.initials: MJ
authors.lastname: Espy
authors.forename: Susan K
authors.initials: SK
authors.lastname: Schneider
authors.forename: Thomas F
authors.initials: TF
authors.lastname: Smith
authors.forename: Bobbi S
authors.initials: BS
authors.lastname: Pritt
mesh_terms: D000328:Adult; D000368:Aged; D019411:Clinical Laboratory Techniques / Q000379:methods*; D015897:Comorbidity; D005260:Female; D006561:Herpes Simplex / Q000453:epidemiology*; D006562:Herpes Zoster / Q000453:epidemiology*; D014645:Herpesvirus 3, Human / Q000235:genetics / Q000302:isolation & purification*; D006801:Humans; D008297:Male; D008875:Middle Aged; D016133:Polymerase Chain Reaction / Q000379:methods*; D015995:Prevalence; D012189:Retrospective Studies; D018139:Simplexvirus / Q000235:genetics / Q000302:isolation & purification*; D014773:Virology / Q000379:methods*