title: Stuttering treatment control using P300 event-related potentials.
abstract: Positron emission tomography studies during speech have indicated a failure to show the normal activation of auditory cortical areas in stuttering individuals. In the present study, P300 event-related potentials were used to investigate possible effects of behavioral treatment on the pattern of signal amplitude and latency between waves. In order to compare variations in P300 measurements, a control group paired by age and gender to the group of stutterers, was included in the study. Findings suggest that the group of stutterers presented a significant decrease in stuttering severity after the fluency treatment program. Regarding P300 measurements, stutterers and their controls presented results within normal limits in all testing situations and no significant statistical variations between pre and post treatment testing. When comparing individual results between the testing situations, stutterers presented a higher average decrease in wave latency for the right ear following treatment. The results are discussed in light of previous P300 event-related potentials and functional imaging studies with stuttering adults.
  
  
  OBJECTIVE
  The reader will learn about and be able to describe the: (1) use of P300 event-related potentials in the study of stuttering; (2) differences between stuttering and non-stuttering adults; and (3) effects of behavioral fluency treatment on cerebral activity in stuttering speakers.
authors.affiliation: Department of Physiotherapy, Speech-Language and Hearing Sciences and Occupational Therapy, School of Medicine, University of São Paulo, Brazil.
authors.forename: Fernanda Chiarion
authors.initials: FC
authors.lastname: Sassi
authors.forename: Carla Gentile
authors.initials: CG
authors.lastname: Matas
authors.forename: Lucia Iracema Zanotto
authors.initials: LI
authors.lastname: de Mendonça
authors.forename: Claudia Regina Furquim
authors.initials: CR
authors.lastname: de Andrade
mesh_terms: D004576:Electromyography; D018913:Event-Related Potentials, P300 / Q000502:physiology*; D005072:Evoked Potentials, Auditory / Q000502:physiology; D006801:Humans; D008297:Male; D013060:Speech / Q000502:physiology; D013070:Speech Therapy; D013342:Stuttering / Q000503:physiopathology* / Q000628:therapy; D055815:Young Adult