title: SCORE model underestimates cardiovascular risk in hypertensive patients: results of the Polish Hypertension Registry.
abstract: OBJECTIVE. The aim of the present study was to compare the effectiveness of Systemic COronary Risk Evaluation (SCORE) charts and European Society of Hypertension/European Society of Cardiology (ESH/ESC) hypertension guidelines for identifying high-risk hypertensive patients. METHODS. The data on hypertensive patients was collected using the Polish Hypertension Registry. We enrolled 636 patients (357 females and 279 males, mean age 54.4 (+/-) 7.9 years) from hypertension centres in Poland. RESULTS. Only 3.5% of the subjects had no additional risk factors. Thirty-six per cent of the patients had three or more risk factors. Metabolic syndrome was found in 40.1% of the patients. According to the SCORE charts, 9.0% of females and 27.2% of males had high to very high cardiovascular risk (p < 0.001). Taking into account risk factors and the metabolic syndrome, 55.7% of females and 56.3% of males (p = NS) had high or very high additional cardiovascular risk according to the 2007 ESH/ESC guidelines. For both females and males, the prevalence of high to very high risk was greater (p < 0.001) from the calculation based on the 2007 ESH/ESC guidelines than from the SCORE charts. Fifty-two per cent of patients classified as low to moderate risk according to the SCORE system, had high or very high risk according to the 2007 ESH/ESC guidelines. CONCLUSIONS. The SCORE charts seem to underestimate the burden of the cardiovascular risk among hypertensive patients. The cardiovascular risk, especially in the hypertensive female population, seems to be much higher when estimated according to the 2007 ESH/ESC guidelines.
authors.affiliation: Hypertension Unit, Dept. Hypertension and Diabetology, Medical University of Gdansk, Poland. anna@amg.gda.pl
authors.forename: Anna
authors.initials: A
authors.lastname: Szyndler
authors.forename: Wies Awa
authors.initials: WA
authors.lastname: Kucharska
authors.forename: And Elina
authors.initials: AE
authors.lastname: Dubiela-D Browska
authors.forename: Agnieszka
authors.initials: A
authors.lastname: Olszanecka
authors.forename: Justyna
authors.initials: J
authors.lastname: Widecka
authors.forename: Miros Awa
authors.initials: MA
authors.lastname: B Czkiewicz
authors.forename: Katarzyna
authors.initials: K
authors.lastname: Widecka
authors.forename: Gra Yna
authors.initials: GY
authors.lastname: Galas
authors.forename: Iwona
authors.initials: I
authors.lastname: Chlebi Ska
authors.forename: Wojciech
authors.initials: W
authors.lastname: Sakiewicz
authors.forename: Zbigniew
authors.initials: Z
authors.lastname: Gaciong
authors.forename: Krystyna
authors.initials: K
authors.lastname: Widecka
authors.forename: Andrzej
authors.initials: A
authors.lastname: Januszewicz
authors.forename: Kalina
authors.initials: K
authors.lastname: Kawecka-Jaszcz
authors.forename: Krzysztof
authors.initials: K
authors.lastname: Narkiewicz
mesh_terms: D000328:Adult; D000368:Aged; D015982:Bias; D002318:Cardiovascular Diseases / Q000150:complications / Q000175:diagnosis* / Q000453:epidemiology / Q000503:physiopathology; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000175:diagnosis* / Q000453:epidemiology / Q000503:physiopathology; D008297:Male; D024821:Metabolic Syndrome / Q000150:complications / Q000175:diagnosis* / Q000453:epidemiology / Q000503:physiopathology; D008875:Middle Aged; D011044:Poland / Q000453:epidemiology; D017410:Practice Guidelines as Topic; D015995:Prevalence; D011379:Prognosis; D012042:Registries; D012107:Research Design; D018570:Risk Assessment / Q000379:methods; D012307:Risk Factors