title: Impact of management and bacterial genomics on outcomes of Staphylococcus aureus bacteremia in children.
abstract: Children with Staphylococcus aureus bacteremia (SAB) generally presented with nonsevere signs and symptoms in sharp contrast to reports of adults with SAB. Despite incomplete adherence to current management guidelines, children with SAB did not experience mortality or relapse. Molecular characteristics of strains responsible for SAB in children were not significantly different than those described in adults. Improved outcomes in pediatric SAB compared with adults may most likely be attributed to less severe comorbidities in children.
authors.affiliation: State University of New York at Buffalo, Buffalo, NY, USA. hfaden@upa.chob.edu
authors.forename: Howard
authors.initials: H
authors.lastname: Faden
authors.forename: Steven
authors.initials: S
authors.lastname: Gill
authors.forename: Alan
authors.initials: A
authors.lastname: Lesse
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D010349:Patient Compliance / Q000706:statistics & numerical data; D011379:Prognosis; D012189:Retrospective Studies; D013203:Staphylococcal Infections / Q000188:drug therapy* / Q000382:microbiology* / Q000401:mortality; D013211:Staphylococcus aureus / Q000187:drug effects / Q000235:genetics*; D016896:Treatment Outcome; D055815:Young Adult