title: Asperaculin A, a sesquiterpenoid from a marine-derived fungus, Aspergillus aculeatus.
abstract: A novel sesquiterpenoid, asperaculin A, possessing a novel [5,5,5,6]fenestrane ring system, was isolated from the marine-derived fungus Aspergillus aculeatus CRI323-04. The structure of asperaculin A was established by analysis of spectroscopic data. The name aspergillane is proposed for the sesquiterpene skeleton in asperaculin A.
authors.affiliation: Chulabhorn Graduate Institute and the Center for Environmental Health, Toxicology and Management of Chemicals (ETM), Chemical Biology Program, Vibhavadi-Rangsit Road, Laksi, Bangkok 10210, Thailand.
authors.forename: Nattha
authors.initials: N
authors.lastname: Ingavat
authors.forename: Chulabhorn
authors.initials: C
authors.lastname: Mahidol
authors.forename: Somsak
authors.initials: S
authors.lastname: Ruchirawat
authors.forename: Prasat
authors.initials: P
authors.lastname: Kittakoop
mesh_terms: D000970:Antineoplastic Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D001230:Aspergillus / Q000737:chemistry*; D004354:Drug Screening Assays, Antitumor; D056945:Hep G2 Cells; D006801:Humans; D008386:Marine Biology; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: D000970:Antineoplastic Agents; D012717:Sesquiterpenes; C561560:asperaculin A