title: Multicentric evaluation of new commercial enzyme immunoassays for the detection of immunoglobulin M and total antibodies against hepatitis A virus.
abstract: A multicentric clinical study was conducted on representative sera from 1,738 European and U.S. subjects for the evaluation of new anti-hepatitis A virus enzyme immunoassays from Bio-Rad Laboratories. Comparison with reference DiaSorin S.p.A. tests confirmed the good performance of Bio-Rad assays (99.85% and 99.47% overall agreement in detecting total antibodies and IgM, respectively).
authors.affiliation: Microbiology Section, Department of Pathology and Laboratory Medicine, University of Parma, Viale Antonio Gramsci 14, 43126 Parma, Italy. mariacristina.arcangeletti@unipr.it
authors.forename: M C
authors.initials: MC
authors.lastname: Arcangeletti
authors.forename: E
authors.initials: E
authors.lastname: Dussaix
authors.forename: F
authors.initials: F
authors.lastname: Ferraglia
authors.forename: A M
authors.initials: AM
authors.lastname: Roque-Afonso
authors.forename: A
authors.initials: A
authors.lastname: Graube
authors.forename: C
authors.initials: C
authors.lastname: Chezzi
mesh_terms: D019411:Clinical Laboratory Techniques / Q000379:methods*; D006506:Hepatitis A / Q000175:diagnosis*; D035922:Hepatitis A Antibodies / Q000097:blood*; D030041:Hepatitis A virus / Q000276:immunology*; D006801:Humans; D007124:Immunoenzyme Techniques / Q000379:methods; D007075:Immunoglobulin M / Q000097:blood*
chemical_list: D035922:Hepatitis A Antibodies; D007075:Immunoglobulin M