title: Metastases to the mouth and jaws: a contemporary Canadian experience.
abstract: OBJECTIVE
  The types of cancers that most frequently metastasize to the mouth and jaws reflect, for the most part, the relative incidence of cancers in a given population at a given time. We report a retrospective, but relatively contemporary study of 38 cases of metastatic oral tumours in a Canadian population to compare the Canadian experience with that of nearby and distant countries.
  
  
  METHODS
  Thirty-eight cases of metastatic disease to the mouth and jaws in a Canadian population were analyzed. Data about patients' age, sex, site of metastatic deposits, clinical history, including the presence of a known primary cancer, and radiographic features were collected from the files (1992-2010) of the oral pathology diagnostic service at the University of Western Ontario, and the hospital archives (2002-2010) of the department of pathology, London Health Sciences Centre, London, Ontario.
  
  
  RESULTS
  Most metastases were to the mandible, although oral soft tissues were also involved, most frequently, the gingiva and mucosa of the alveolar ridge. Prostate, lung and breast cancers were the most common primary sites, but a variety of cancer types were found.
  
  
  CONCLUSIONS
  The relative frequency of types of metastatic cancer to the oral region is similar in Canada, the United States and Northern Europe, but differs significantly from those reported in South East Asia and Japan. The relative frequency of types of cancer that metastasize to the mouth and jaws reflects the relative incidence of cancers in the population.
authors.affiliation: Department of Pathology, University of Western Ontario, London, ON. tdaley@schulich.uwo.ca
authors.forename: Tom
authors.initials: T
authors.lastname: Daley
authors.forename: Mark R
authors.initials: MR
authors.lastname: Darling
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001706:Biopsy; D005260:Female; D006801:Humans; D007573:Jaw Neoplasms / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000556:secondary*; D008297:Male; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000556:secondary*; D009864:Ontario / Q000453:epidemiology; D011859:Radiography; D012189:Retrospective Studies