title: Recurrent metanephric stromal tumor in an infant.
abstract: A 9-month-old boy underwent nephrectomy for a renal mass. Congenital mesoblastic nephroma was diagnosed, and the patient received postoperative chemotherapy. Tumor recurred 6 months later as a scrotal mass. After orchiectomy, diagnosis of metanephric stromal tumor (MST) was made; review of the nephrectomy specimens confirmed this diagnosis. No additional treatment was given, and the child is alive and well 31 months later. Taking into account the histopathological entity of MST in the differential diagnosis of stromal renal tumors in childhood can spare the patient further, potentially toxic, treatment even in the case of relapse, as reported here for the first time.
authors.affiliation: Department of Hematology-Oncology, Istituto di Ricovero e Cura a Carattere Scientifico, Bambino Gesù Children's Hospital, Rome, Italy. mdebora.depasquale@opbg.net
authors.forename: Maria Debora
authors.initials: MD
authors.lastname: De Pasquale
authors.forename: Francesca
authors.initials: F
authors.lastname: Diomedi-Camassei
authors.forename: Annalisa
authors.initials: A
authors.lastname: Serra
authors.forename: Renata
authors.initials: R
authors.lastname: Boldrini
authors.forename: Alessandro
authors.initials: A
authors.lastname: Inserra
authors.forename: Paolo
authors.initials: P
authors.lastname: Caione
authors.forename: Alessandro
authors.initials: A
authors.lastname: Jenkner
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D003609:Dactinomycin / Q000008:administration & dosage; D003937:Diagnosis, Differential; D006801:Humans; D007223:Infant; D007680:Kidney Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D008297:Male; D018201:Nephroma, Mesoblastic / Q000473:pathology* / Q000601:surgery; D017154:Stromal Cells / Q000473:pathology*; D013736:Testicular Neoplasms / Q000473:pathology* / Q000601:surgery; D014750:Vincristine / Q000008:administration & dosage
chemical_list: D003609:Dactinomycin; D014750:Vincristine