title: Myxoedema coma.
abstract: Myxoedema coma is a rare and extreme presentation of hypothyroidism. It has a poor prognosis due to multisystem decompensation, and demands prompt but careful management in a high-dependency / intensive care setting. Early recognition of hypercapnia, hyponatraemia, and sepsis are especially important. Treatment should begin on suspicion of the diagnosis and can be life-saving. Intravenous thyroid hormone replacement is required at first, with steroid cover, although the optimum dose regimen remains unclear.
authors.affiliation: Dept. of Diabetes and Endocrinology, E-Level, North Hampshire Hospital, Aldermaston Road, Basingstoke, Hants RG24 9LN.
authors.forename: B
authors.initials: B
authors.lastname: Turner