title: Eating disorders and trauma history in women with perinatal depression.
abstract: OBJECTIVE
  Although the prevalence of perinatal depression (depression occurring during pregnancy and postpartum) is 10%, little is known about psychiatric comorbidity in these women. We examined the prevalence of comorbid eating disorders (ED) and trauma history in women with perinatal depression.
  
  
  METHODS
  A research questionnaire was administered to 158 consecutive patients seen in a perinatal psychiatry clinic during pregnancy (n=99) or postpartum (n=59). Measures included Structured Clinical Interview for DSM (SCID) IV-based questions for lifetime eating psychopathology and assessments of comorbid psychiatric illness including the State/Trait Anxiety Inventory (STAI), Patient Health Questionnaire (PHQ-9), Edinburgh Postnatal Depression Scale (EPDS), and Trauma Inventory.
  
  
  RESULTS
  In this cohort, 37.1% reported a putative lifetime ED history; 10.1% reported anorexia nervosa (AN), 10.1% reported bulimia nervosa (BN), 10.1% reported ED not otherwise specified-purging subtype (EDNOS-P), and 7.0% reported binge eating disorder (BED). Women with BN reported more severe depression (EPDS score, 19.1, standard deviation [SD 4.3], p=0.02; PHQ-severity 14.5, SD 7.4, p=0.02) than the referent group of women with perinatal depression and no ED history (EPDS 13.3, SD=6.1; PHQ 9.0, SD=6.2). Women with AN were more likely to report sexual trauma history than the referent group (62.5% vs. 29.3%, p<0.05), and those with BN were more likely report physical (50.0%, p<0.05) and sexual (66.7%, p<0.05) trauma histories.
  
  
  CONCLUSIONS
  ED histories were present in over one third of admissions to a perinatal psychiatry clinic. Women with BN reported more severe depression and histories of physical and sexual trauma. Screening for histories of eating psychopathology is important in women with perinatal depression.
authors.affiliation: Department of Psychiatry, University of North Carolina at Chapel Hill, NC 27599, USA. meltzerb@med.une.edu
authors.forename: Samantha
authors.initials: S
authors.lastname: Meltzer-Brody
authors.forename: Stephanie
authors.initials: S
authors.lastname: Zerwas
authors.forename: Jane
authors.initials: J
authors.lastname: Leserman
authors.forename: Ann Von
authors.initials: AV
authors.lastname: Holle
authors.forename: Taylor
authors.initials: T
authors.lastname: Regis
authors.forename: Cynthia
authors.initials: C
authors.lastname: Bulik
mesh_terms: D000328:Adult; D001007:Anxiety / Q000453:epidemiology / Q000523:psychology; D019052:Depression, Postpartum; D003866:Depressive Disorder / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology* / Q000523:psychology*; D001068:Feeding and Eating Disorders / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology* / Q000523:psychology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009657:North Carolina / Q000453:epidemiology; D018743:Perinatal Care; D011247:Pregnancy; D011248:Pregnancy Complications / Q000453:epidemiology* / Q000523:psychology*; D011569:Psychiatric Status Rating Scales; D012742:Sex Offenses / Q000523:psychology / Q000706:statistics & numerical data; D011795:Surveys and Questionnaires; D055815:Young Adult