title: Steroid myopathy: some unresolved issues.
abstract: Steroid myopathy is a non-inflammatory toxic myopathy that occurs as side effect of exogenous and endogenous glucocorticoid excess. The purpose of this review is to examine issues that limit our understanding of this myopathy with respect to nosology, etiopathogenesis, conditioning factors, and muscle fiber selectivity. We suggest that if more data were available on these issues, the understanding of steroid myopathy would be enhanced substantially, thus allowing an early detection of its occurrence (before the appearance of clinical or laboratory signs) and a proper treatment of the patients.
authors.affiliation: Division of Endocrinology, Diabetology and Metabolism, Department of Internal Medicine, University of Turin, Turin, Italy. marcominetto@libero.it
authors.forename: M A
authors.initials: MA
authors.lastname: Minetto
authors.forename: F
authors.initials: F
authors.lastname: Lanfranco
authors.forename: G
authors.initials: G
authors.lastname: Motta
authors.forename: S
authors.initials: S
authors.lastname: Allasia
authors.forename: E
authors.initials: E
authors.lastname: Arvat
authors.forename: G
authors.initials: G
authors.lastname: D'Antona
mesh_terms: D000818:Animals; D003480:Cushing Syndrome / Q000150:complications* / Q000473:pathology / Q000503:physiopathology / Q000628:therapy; D006801:Humans; D018482:Muscle, Skeletal / Q000187:drug effects* / Q000473:pathology*; D009135:Muscular Diseases / Q000139:chemically induced* / Q000453:epidemiology / Q000473:pathology / Q000503:physiopathology; D013256:Steroids / Q000009:adverse effects*
chemical_list: D013256:Steroids