title: Bone metabolism of residual ridge beneath the denture base of an RPD observed using NaF-PET/CT.
abstract: METHODS
  A 66-year-old woman, who had a bilateral free-end edentulous mandible and no experience with dentures, was examined for the chief complaint of masticatory dysfunction on left side of dental arch. A unilateral distal extension removable partial denture (RPD) replacing lower-left molars was selected. Tomographic images were obtained using Fluorine-18 NaF positron emission computerized tomography (NaF-PET)/computed tomography (CT) before the RPD use and at 1, 6, and 13 weeks after the RPD use to observe the metabolic changes in residual bone caused by the RPD use. PET standardized uptake values (SUVs) and CT values were calculated for lower-left edentulous site (test side) and lower-right edentulous site (control side). As a result, SUVs on the control side remained static after the RPD use, whereas those on the test side increased at 1 and 6 weeks after the RPD use and then decreased. However, CT images showed no obvious changes in the bone shape and structure beneath RPD, and CT values both on the control and test sides did not change either.
  
  
  CONCLUSIONS
  This report shows that NaF-PET could detect bone metabolic changes soon after the RPD use, which cannot be detected by clinical X-rays. The SUV changes may be a mechanobiological reaction to the pressure due to the RPD use, and wearing of the RPD may increase the bone turnover beneath denture.
  
  
  CONCLUSIONS
  This report demonstrates that wearing of an RPD increases bone turnover beneath denture immediately after the RPD use without clinically detectable changes in bone structure or volume.
authors.affiliation: Division of Advanced Prosthetic Dentistry, Tohoku University Graduate School of Dentistry, 4-1 Seiryo-machi, Aoba-ku, Sendai, 980-8575, Japan. suenaga-thk@umin.ac.jp
authors.forename: Hanako
authors.initials: H
authors.lastname: Suenaga
authors.forename: Masayoshi
authors.initials: M
authors.lastname: Yokoyama
authors.forename: Keiichiro
authors.initials: K
authors.lastname: Yamaguchi
authors.forename: Keiichi
authors.initials: K
authors.lastname: Sasaki
mesh_terms: D000368:Aged; D003832:Denture, Partial, Removable / Q000009:adverse effects*; D005260:Female; D005462:Fluorine Radioisotopes; D006801:Humans; D007575:Jaw, Edentulous / Q000000981:diagnostic imaging* / Q000378:metabolism; D008334:Mandible / Q000000981:diagnostic imaging* / Q000378:metabolism*; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals; D012969:Sodium Fluoride; D014057:Tomography, X-Ray Computed
chemical_list: D005462:Fluorine Radioisotopes; D019275:Radiopharmaceuticals; D012969:Sodium Fluoride