title: SGK3: a novel regulator of renal phosphate transport?
abstract: Phosphate is a key constituent of several important molecules, and hyperphospatemia has been associated with increased cardiovascular mortality. The kidney plays a crucial role in phosphate metabolism, as it is able to modulate phosphate excretion. Serum- and glucocorticoid-inducible kinase 3 (SGK3) has been shown to regulate a wide variety of transport systems. Bhandaru et al. suggest that SGK3 may have a significant role in the regulation of renal tubular phosphate transport.
authors.affiliation: Section of Nephrology, Department of Internal Medicine, Second University of Naples, Naples, Italy.
authors.forename: Francesco
authors.initials: F
authors.lastname: Trepiccione
authors.forename: Giovambattista
authors.initials: G
authors.lastname: Capasso
mesh_terms: D000818:Animals; D015519:Bone Density / Q000502:physiology*; D005260:Female; D006801:Humans; D007015:Hypophosphatemia, Familial / Q000209:etiology*; D017346:Protein Serine-Threonine Kinases / Q000172:deficiency*; D000099184:Serum-Glucocorticoid Regulated Kinases
chemical_list: D017346:Protein Serine-Threonine Kinases; C523602:Sgk3 protein, mouse; D000099184:Serum-Glucocorticoid Regulated Kinases