title: MR imaging of articular cartilage physiology.
abstract: The newer magnetic resonance (MR) imaging methods can give insights into the initiation, progression, and eventual treatment of osteoarthritis. Sodium imaging is specific for changes in proteoglycan (PG) content without the need for an exogenous contrast agent. T1ρ imaging is sensitive to early PG depletion. Delayed gadolinium-enhanced MR imaging has high resolution and sensitivity. T2 mapping is straightforward and is sensitive to changes in collagen and water content. Ultrashort echo time MR imaging examines the osteochondral junction. Magnetization transfer provides improved contrast between cartilage and fluid. Diffusion-weighted imaging may be a valuable tool in postoperative imaging.
authors.affiliation: Department of Radiology, Stanford University, 300 Pasteur Drive, Stanford, CA 94305, USA.
authors.forename: Jung-Ah
authors.initials: JA
authors.lastname: Choi
authors.forename: Garry E
authors.initials: GE
authors.lastname: Gold
mesh_terms: D016880:Anisotropy; D001696:Biomechanical Phenomena; D002357:Cartilage Diseases / Q000503:physiopathology; D002358:Cartilage, Articular / Q000737:chemistry / Q000502:physiology*; D003287:Contrast Media; D006801:Humans; D007718:Knee Injuries / Q000503:physiopathology; D007719:Knee Joint / Q000503:physiopathology; D008279:Magnetic Resonance Imaging / Q000379:methods*; D020370:Osteoarthritis, Knee / Q000503:physiopathology; D013314:Stress, Mechanical
chemical_list: D003287:Contrast Media