title: Case of primary biliary cirrhosis-autoimmune hepatitis overlap which manifested after delivery.
abstract: A 34-year-old woman showed liver dysfunction for the first time at 3 months after delivery. Two years later, she was referred to our department with continued liver dysfunction. She fulfilled the criteria for primary biliary cirrhosis (PBC)-autoimmune hepatitis (AIH) overlap. Liver dysfunction improved after administration of ursodeoxycholic acid and bezafibrate. To the best of our knowledge this represents the second report of PBC-AIH overlap after delivery and we discuss immunological changes during the perinatal period.
authors.affiliation: Department of Gastroenterology and Rheumatology, Fukushima Medical University School of Medicine, Japan.
authors.forename: Kyoko
authors.initials: K
authors.lastname: Monoe
authors.forename: Atsushi
authors.initials: A
authors.lastname: Takahashi
authors.forename: Fumiko
authors.initials: F
authors.lastname: Katsushima
authors.forename: Yukiko
authors.initials: Y
authors.lastname: Kanno
authors.forename: Hironobu
authors.initials: H
authors.lastname: Saito
authors.forename: Kazumichi
authors.initials: K
authors.lastname: Abe
authors.forename: Junko
authors.initials: J
authors.lastname: Yokokawa
authors.forename: Hiromasa
authors.initials: H
authors.lastname: Ohira
mesh_terms: D000328:Adult; D001629:Bezafibrate / Q000627:therapeutic use; D002756:Cholagogues and Choleretics / Q000627:therapeutic use; D005260:Female; D019693:Hepatitis, Autoimmune / Q000150:complications* / Q000188:drug therapy / Q000276:immunology; D006801:Humans; D008105:Liver Cirrhosis, Biliary / Q000150:complications* / Q000188:drug therapy / Q000276:immunology; D049590:Postpartum Period / Q000276:immunology*; D011247:Pregnancy; D014580:Ursodeoxycholic Acid / Q000627:therapeutic use
chemical_list: D002756:Cholagogues and Choleretics; D014580:Ursodeoxycholic Acid; D001629:Bezafibrate