title: [Analysis of horizontal transfer gene of Bombyx mori NPV].
abstract: For research on genetic characters and evolutionary origin of the genome of baculoviruses, a comprehensive homology search and phylogenetic analysis of the complete genomes of Bombyx mori NPV and Bombyx mori were used. Three horizontally transferred genes (inhibitor of apoptosis, chitinase, and UDP-glucosyltransferase) were identified, and there was evidence that all of these genes were derived from the insect host. The results of analysis showed lots of differences between the features of horizontal transferred genes and the ones of whole genomic genes, such as nucleotide composition, codon usagebias and selection pressure. These results reconfirmed that the horizontally transferred genes are exogenous. The analysis of gene function suggested that horizontally transferred genes acquired from an ancestral host insect can increase the efficiency of baculoviruses transmission.
authors.affiliation: Center for Systems Biology of Soochow University, Suzhou 215006, China. melissa.duan@hotmail.com
authors.forename: Hai-Rong
authors.initials: HR
authors.lastname: Duan
authors.forename: De-Bin
authors.initials: DB
authors.lastname: Qiu
authors.forename: Cheng-Liang
authors.initials: CL
authors.lastname: Gong
authors.forename: Mo-Li
authors.initials: ML
authors.lastname: Huang
mesh_terms: D000818:Animals; D012831:Bombyx / Q000821:virology*; D019143:Evolution, Molecular; D022761:Gene Transfer, Horizontal; D005814:Genes, Viral / Q000235:genetics; D023281:Genomics / Q000379:methods*; D017924:Nucleopolyhedroviruses / Q000235:genetics*; D010802:Phylogeny; D012641:Selection, Genetic; D012984:Software