title: Stereodivergent ruthenium-catalyzed transfer semihydrogenation of diaryl alkynes.
abstract: [Ru(3)(CO)(12)]-catalyzed transfer semihydrogenation of various functionalized diaryl alkynes with N,N-dimethylformamide (DMF) and water as hydrogen source affords cis- and trans-stilbenes. The stereodivergent approach can be switched by the use of acetic (HOAc) or trifluoroacetic (TFA) acid as additives. The catalytic processes can be applied to the synthesis of analogues of natural products such as cis-combretastatin A-4 and trans-resveratrol.
authors.affiliation: Department of Chemistry, Tsinghua University, Key Laboratory of Organic Optoelectronics & Molecular Engineering of Ministry of Education, Beijing 100084, P. R. of China.
authors.forename: Jie
authors.initials: J
authors.lastname: Li
authors.forename: Ruimao
authors.initials: R
authors.lastname: Hua
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D002384:Catalysis; D006865:Hydrogenation; D015394:Molecular Structure; D012428:Ruthenium / Q000737:chemistry*
chemical_list: D000480:Alkynes; D012428:Ruthenium