title: [Stem cells in cardiological clinical trials].
abstract: Stem cell-based therapy is a novel therapeutic strategy introduced into cardiology, although there are not any established standards within the stem/progenitor cell type employed, their preparation, rout of administration as well as methods controlling the pathophysiological and clinical parameters after the cell application. The aim of the present work was a complex meta-analysis of the clinical trials carried out in this field. Over 1000 patients with myocardial infarction as well as circulatory failure have been treated with stem cell-based therapy so far, but the obtained results are not concordant. Progress within cell biology and biotechnology give hopes for development of more effective therapeutic approaches. Identification and isolation of cardiac- -specific stem/progenitor cells may deliver new perspectives for such therapy in the nearest future.
authors.affiliation: Klinika Kardiologii, Pomorski Uniwersytet Medyczny, Szczecin. kppam@wp.pl
authors.forename: Krzysztof
authors.initials: K
authors.lastname: Przybycień
authors.forename: Zdzisława
authors.initials: Z
authors.lastname: Kornacewicz Jach
authors.forename: Bogusław
authors.initials: B
authors.lastname: Machaliński
mesh_terms: D035843:Biomedical Research; D002309:Cardiology; D002318:Cardiovascular Diseases / Q000601:surgery*; D006801:Humans; D033581:Stem Cell Transplantation; D013234:Stem Cells; D016896:Treatment Outcome