title: RNA silencing pathways of plants: silencing and its suppression by plant DNA viruses.
abstract: RNA silencing refers to processes that depend on small (s)RNAs to regulate the expression of eukaryotic genomes. In plants, these processes play critical roles in development, in responses to a wide array of stresses, in maintaining genome integrity and in defense against viral and bacterial pathogens. We provide here an updated view on the array of endogenous sRNA pathways, including microRNAs (miRNAs), discovered in the model plant Arabidopsis, which are also the basis for antiviral silencing. We emphasize the current knowledge as well as the recent advances made on understanding the defense and counter-defense strategies evolved in the arms race between plants and DNA viruses on both the nuclear and the cytoplasmic front. This article is part of a Special Issue entitled: MicroRNA's in viral gene regulation.
authors.affiliation: Institute of Botany, University of Basel, Basel, Switzerland. hohn@fmi.ch
authors.forename: Thomas
authors.initials: T
authors.lastname: Hohn
authors.forename: Franck
authors.initials: F
authors.lastname: Vazquez
mesh_terms: D017360:Arabidopsis / Q000235:genetics / Q000378:metabolism / Q000821:virology; D004267:DNA Viruses / Q000737:chemistry*; D018744:DNA, Plant / Q000737:chemistry*; D018506:Gene Expression Regulation, Plant; D010942:Plant Viruses / Q000235:genetics* / Q000378:metabolism; D034622:RNA Interference; D018749:RNA, Plant / Q000737:chemistry; D034741:RNA, Small Interfering / Q000737:chemistry; D014764:Viral Proteins / Q000235:genetics / Q000378:metabolism
chemical_list: D018744:DNA, Plant; D018749:RNA, Plant; D034741:RNA, Small Interfering; D014764:Viral Proteins