title: Profiling of phenolics from Tephrosia cinerea.
abstract: An HPLC-ESIMS(n) method, based on high-performance liquid chromatography coupled to electrospray positive ionization multistage ion trap mass spectrometry, has been used to rapidly identify and guide the isolation of phenolic constituents from the methanol extract of the aerial parts of T. cinerea. On the basis of the results of the online screening by HPLC-ESIMS (n), 17 phenolic constituents, including two new compounds, namely demethylapollinin 7- O- β-D-glucopyranoside (1) and cineroside A (17), were isolated, and their structures were unambiguously assigned by the extensive use of 1D- and 2D-NMR experiments.
authors.affiliation: Dipartimento di Scienze Farmaceutiche e Biomediche, Università degli Studi di Salerno, Fisciano, Italy. piacente@unisa.it
authors.forename: Mariateresa
authors.initials: M
authors.lastname: Maldini
authors.forename: Paola
authors.initials: P
authors.lastname: Montoro
authors.forename: Mario
authors.initials: M
authors.lastname: Macchia
authors.forename: Cosimo
authors.initials: C
authors.lastname: Pizza
authors.forename: Sonia
authors.initials: S
authors.lastname: Piacente
mesh_terms: D002851:Chromatography, High Pressure Liquid; D009682:Magnetic Resonance Spectroscopy; D009005:Monosaccharides / Q000737:chemistry / Q000302:isolation & purification; D010636:Phenols / Q000737:chemistry* / Q000302:isolation & purification; D010666:Phenylpropionates / Q000737:chemistry / Q000302:isolation & purification; D035261:Plant Components, Aerial / Q000737:chemistry; D010936:Plant Extracts / Q000737:chemistry* / Q000302:isolation & purification; D021241:Spectrometry, Mass, Electrospray Ionization; D031304:Tephrosia / Q000737:chemistry*
chemical_list: C579603:3-O-(2-O-beta-D-glucopyranosyloxy-5-hydroxyphenoxy)-3-phenylpropanoic acid; D009005:Monosaccharides; D010636:Phenols; D010666:Phenylpropionates; D010936:Plant Extracts; C579598:demethylapollinin 7-O-beta-D-glucopyranoside