title: [Sentinel lymph node biopsy after neoadjuvant chemotherapy in breast cancer].
abstract: The indication of neoadjuvant chemotherapy has been recently extended; it is now applied not only in locally advanced breast cancer but in primarily resecable tumours as well, in order to promote breast conservation. Based on recent clinical results, the reconsideration of traditional lymph node dissection in axillary staging is timely in patients receiving neoadjuvant chemotherapy. Precise axillary staging needs surgical removal of lymph nodes. Based on prospective randomised trials, sentinel lymph node biopsy appears to be appropriate for axillary staging even in tumours requiring neoadjuvant treatment. The extended indication of sentinel lymph node biopsy raises several questions and problems. In the present paper the authors review the results and possible limitations of sentinel lymph node biopsy in relation to neoadjuvant chemotherapy.
authors.affiliation: Általános és Mellkassebészeti Osztály, Országos Onkológiai Intézet, Budapest, Hungary. matraidok@freemail.hu
authors.forename: Zoltán
authors.initials: Z
authors.lastname: Mátrai
authors.forename: László
authors.initials: L
authors.lastname: Tóth
authors.forename: Csaba
authors.initials: C
authors.lastname: Polgár
authors.forename: István
authors.initials: I
authors.lastname: Láng
authors.forename: Mária
authors.initials: M
authors.lastname: Gõdény
authors.forename: István
authors.initials: I
authors.lastname: Sinkovics
authors.forename: Zsolt
authors.initials: Z
authors.lastname: Horváth
authors.forename: Mária
authors.initials: M
authors.lastname: Bidlek
authors.forename: Nóra
authors.initials: N
authors.lastname: Udvarhelyi
authors.forename: Alexandra
authors.initials: A
authors.lastname: Bartal
authors.forename: Akos
authors.initials: A
authors.lastname: Sávolt
authors.forename: Mihály
authors.initials: M
authors.lastname: Ujhelyi
authors.forename: Miklós
authors.initials: M
authors.lastname: Kásler
mesh_terms: D000465:Algorithms; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001365:Axilla; D001943:Breast Neoplasms / Q000188:drug therapy* / Q000473:pathology* / Q000601:surgery; D017024:Chemotherapy, Adjuvant; D005260:Female; D006801:Humans; D008197:Lymph Node Excision; D008198:Lymph Nodes / Q000473:pathology* / Q000601:surgery; D008207:Lymphatic Metastasis / Q000175:diagnosis; D020360:Neoadjuvant Therapy / Q000379:methods*; D009367:Neoplasm Staging; D011237:Predictive Value of Tests; D011379:Prognosis; D021701:Sentinel Lymph Node Biopsy