title: A meta-analysis of the fixed-bearing and mobile-bearing prostheses in total knee arthroplasty.
abstract: BACKGROUND
  We asked whether the mobile-bearing knee prostheses could offer clinical and radiographic advantages over the fixed-bearing knee prostheses.
  
  
  METHODS
  We conducted a systematic review and meta-analysis to evaluate the validity of this theory. We searched PubMed, EMBASE, Ovid and the Cochrane Central Register of Controlled Trials from January 1979 to June 2010 for randomized controlled studies comparing the effect of fixed- and mobile-bearing prostheses in TKA. We assessed the methodological quality of the studies and abstracted the relevant data independently.
  
  
  RESULTS
  15 studies involving 1,950 knees were identified in this analysis. No statistically significant difference was present in terms of KSS, patient preference, radiolucent line around implant and prosthesis-related complications as compared to the fixed- and mobile-bearing knee design.
  
  
  CONCLUSIONS
  Theoretically, mobile-bearing implant design could improve clinical and radiographic outcomes as being compared to fixed-bearing implant design, but the anticipated effectiveness has not been implemented in the current clinical practice at mid-term follow up.
authors.affiliation: Basic Medical College, China Medical University, Shenyang, Liaoning, China.
authors.forename: Yu
authors.initials: Y
authors.lastname: Wen
authors.forename: Da
authors.initials: D
authors.lastname: Liu
authors.forename: Ying
authors.initials: Y
authors.lastname: Huang
authors.forename: Bin
authors.initials: B
authors.lastname: Li
mesh_terms: D019645:Arthroplasty, Replacement, Knee / Q000295:instrumentation*; D006801:Humans; D007720:Knee Prosthesis; D017060:Patient Satisfaction; D011183:Postoperative Complications; D011474:Prosthesis Design; D011475:Prosthesis Failure; D016032:Randomized Controlled Trials as Topic; D016059:Range of Motion, Articular / Q000502:physiology; D016474:Weight-Bearing / Q000502:physiology