title: Assessing the need for a standardized cancer HUman Biobank (caHUB): findings from a national survey with cancer researchers.
abstract: BACKGROUND
  Before developing a national standardized cancer HUman Biobank (caHUB), the National Cancer Institute sought feedback from the cancer research community.
  
  
  METHODS
  NCI conducted an online survey (N = 727) about current biospecimen needs and reactions to creating a national resource cancer researchers and others.
  
  
  RESULTS
  Most (56%) participants obtained biospecimens within their own institutions, and 63% wanted more information about their biospecimens. Large proportions reported difficulty obtaining biospecimens of adequate numbers (39%) and quality (47%). Low-quality biospecimens resulted in 60% questioning their findings and 81% limiting the scope of their work. Nine in every 10 (91.3%) respondents reacted positively to the idea of a national biospecimen resource, with 62% reporting that they would obtain biospecimens from it and 53% reporting that they would be willing to contribute biospecimens to it.
  
  
  CONCLUSIONS
  Initial reactions to caHUB were positive and seen as a feasible option to addressing respondents' research challenges. National Cancer Institute will need to address several concerns to assure its adoption, including standardization and sustainability.
authors.affiliation: Office of Market Research and Evaluation, Office of Communications and Education, National Cancer Institute, NIH, DHHS, Rockville, MD 20852, USA. massetth@mail.nih.gov
authors.forename: Holly A
authors.initials: HA
authors.lastname: Massett
authors.forename: Nancy L
authors.initials: NL
authors.lastname: Atkinson
authors.forename: Deanne
authors.initials: D
authors.lastname: Weber
authors.forename: Renate
authors.initials: R
authors.lastname: Myles
authors.forename: Colleen
authors.initials: C
authors.lastname: Ryan
authors.forename: Meredith
authors.initials: M
authors.lastname: Grady
authors.forename: Carolyn
authors.initials: C
authors.lastname: Compton
mesh_terms: D003625:Data Collection / Q000379:methods / Q000706:statistics & numerical data; D006301:Health Services Needs and Demand / Q000706:statistics & numerical data*; D006801:Humans; D054547:National Cancer Institute (U.S.); D009369:Neoplasms / Q000235:genetics / Q000378:metabolism* / Q000473:pathology; D012015:Reference Standards; D012107:Research Design; D012108:Research Personnel / Q000706:statistics & numerical data; D014015:Tissue Banks / Q000458:organization & administration / Q000592:standards*; D014481:United States