title: Molecular data of UL24 homolog gene (ORF37) from Brazilian isolates of equine herpesvirus type 1.
abstract: Equine herpesvirus type 1 (EHV-1) is associated with abortions, respiratory distress, and neurological disturbances in horses. The ORF37 of EHV-1 encodes a protein homolog to UL24 gene product of human herpesvirus that has been associated with neurovirulence. In the present work, ORF37 PCR fragments derived from two Brazilian EHV-1 isolates, a German isolate and an American reference strain were sequenced and characterized by molecular phylogenetic analysis. This genomic region is highly conserved an allowed to infer genetic distances between EHV-1 strains and other animal herpesvirus.
authors.affiliation: Laboratório de Genética, Instituto Butantan, São Paulo, SP, CEP 05503-900, Brazil. rodsfc@uol.com.br
authors.forename: R F
authors.initials: RF
authors.lastname: Carvalho
authors.forename: F R
authors.initials: FR
authors.lastname: Spilki
authors.forename: E M
authors.initials: EM
authors.lastname: Cunha
authors.forename: R C
authors.initials: RC
authors.lastname: Stocco
authors.forename: C W
authors.initials: CW
authors.lastname: Arns
mesh_terms: D000818:Animals; D001483:Base Sequence; D001938:Brazil; D005814:Genes, Viral / Q000235:genetics*; D006566:Herpesviridae Infections / Q000662:veterinary / Q000821:virology; D004861:Herpesvirus 1, Equid / Q000235:genetics* / Q000302:isolation & purification; D006734:Horse Diseases / Q000821:virology; D006736:Horses / Q000821:virology; D008969:Molecular Sequence Data; D010802:Phylogeny; D016133:Polymerase Chain Reaction / Q000662:veterinary; D016415:Sequence Alignment; D017422:Sequence Analysis, DNA; D012689:Sequence Homology, Nucleic Acid; D014764:Viral Proteins / Q000235:genetics
chemical_list: D014764:Viral Proteins