title: Use of 2-[18F]fluoro-2-deoxy-D-glucose positron emission tomography in patients with Hodgkin lymphoma in daily practice: a population-based study from Northern Italy.
abstract: We conducted a population-based study to assess how positron emission tomography (PET) is currently used in patients with Hodgkin lymphoma (HL). Four cancer registries from northern Italy were used to identify patients with HL diagnosed from 2006 to 2008. Computed tomography (CT) and PET scans were collected before treatment start (B), at the end (F), and during treatment (I). One hundred and thirty-six patients were identified as the study population. B-PET, I-PET, and F-PET were performed in 82%, 65%, and 85% of patients, respectively. Overall, I-PET was coded as positive in 16% of cases. F-PET was positive in 13% of cases. The I-PET result was a prognostic factor for failure-free survival (FFS) (hazard ratio [HR] 5.33); the F-PET result was the only prognostic factor for overall survival (OS) (HR 14.2). This population-based study confirms the prognostic role of I-PET for FFS also in daily practice; the results of F-PET can be used to predict OS.
authors.affiliation: Dipartimento di Oncologia ed Ematologia, Università di Modena e Reggio Emilia, Modena, Italy. sluminari@unimore.it
authors.forename: Stefano
authors.initials: S
authors.lastname: Luminari
authors.forename: Marina
authors.initials: M
authors.lastname: Cesaretti
authors.forename: Chiara
authors.initials: C
authors.lastname: Tomasello
authors.forename: Annalisa
authors.initials: A
authors.lastname: Guida
authors.forename: Bruno
authors.initials: B
authors.lastname: Bagni
authors.forename: Francesco
authors.initials: F
authors.lastname: Merli
authors.forename: Raffaella
authors.initials: R
authors.lastname: Postiglione
authors.forename: Lucia
authors.initials: L
authors.lastname: Mangone
authors.forename: Annibale
authors.initials: A
authors.lastname: Versari
authors.forename: Francesca
authors.initials: F
authors.lastname: Re
authors.forename: Vincenzo
authors.initials: V
authors.lastname: De Lisi
authors.forename: Livia
authors.initials: L
authors.lastname: Ruffini
authors.forename: Stefano
authors.initials: S
authors.lastname: Ferretti
authors.forename: Antonio
authors.initials: A
authors.lastname: Cuneo
authors.forename: Massimo
authors.initials: M
authors.lastname: Federico
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D019788:Fluorodeoxyglucose F18; D006689:Hodgkin Disease / Q000000981:diagnostic imaging* / Q000401:mortality / Q000473:pathology / Q000628:therapy; D006801:Humans; D007558:Italy; D053208:Kaplan-Meier Estimate; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D049268:Positron-Emission Tomography; D011379:Prognosis; D019275:Radiopharmaceuticals; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18