title: Respiratory fluoroquinolone use and influenza.
abstract: We show that respiratory fluoroquinolone use is extremely seasonal and that fluoroquinolone use is strongly associated with influenza. In our time series model, instantaneous influenza activity was a significant predictor of use (P < .0001). Also, we estimated that reducing influenza activity by 20% would reduce prescriptions by 8%.
authors.affiliation: Division of Infectious Diseases, Department of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa City, Iowa 52242, USA. philip-polgreen@uiowa.edu
authors.forename: Philip M
authors.initials: PM
authors.lastname: Polgreen
authors.forename: Ming
authors.initials: M
authors.lastname: Yang
authors.forename: Ramanan
authors.initials: R
authors.lastname: Laxminarayan
authors.forename: Joseph E
authors.initials: JE
authors.lastname: Cavanaugh
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D004363:Drug Utilization / Q000706:statistics & numerical data; D024841:Fluoroquinolones / Q000627:therapeutic use*; D006801:Humans; D057970:Inappropriate Prescribing; D007251:Influenza, Human / Q000453:epidemiology*; D012044:Regression Analysis; D012141:Respiratory Tract Infections / Q000188:drug therapy / Q000453:epidemiology; D012621:Seasons; D014481:United States / Q000453:epidemiology
chemical_list: D000900:Anti-Bacterial Agents; D024841:Fluoroquinolones