title: [B-cell lymphoma in a woman with chronic hepatitis C and mixed cryoglobulinemia of type 2].
abstract: A report is presented of a rare case of B-cell non-Hodgkin's lymphoma and severe exacerbation of cryoglobulinic vasculitis which developed in a female patient with chronic hepatitis C four years after achievement of a persistent virusological response to antivirus treatment. Causes of a specific course of the disease and development of the tumor in the absence of HCV in blood serum are discussed: latent HCV-infection in immune cells with persistent antigenic stimulation of B-lymphocytes, possibility of HCV-independent lymphoproliferation.
authors.forename: T M
authors.initials: TM
authors.lastname: Ignatova
authors.forename: S Iu
authors.initials: SIu
authors.lastname: Milovanova
authors.forename: O A
authors.initials: OA
authors.lastname: Chernova
authors.forename: Zh Zh
authors.initials: ZhZh
authors.lastname: Baĭzhanova
mesh_terms: D000328:Adult; D001402:B-Lymphocytes / Q000473:pathology; D001706:Biopsy; D003449:Cryoglobulinemia / Q000150:complications* / Q000175:diagnosis; D004279:DNA, Viral / Q000032:analysis; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D016174:Hepacivirus / Q000235:genetics; D019698:Hepatitis C, Chronic / Q000150:complications* / Q000175:diagnosis / Q000821:virology; D006801:Humans; D016393:Lymphoma, B-Cell / Q000150:complications* / Q000175:diagnosis
chemical_list: D004279:DNA, Viral