title: Seco-eremophiladiolides and eremophilane glucosides from Pittocaulon velatum.
abstract: Two seco-eremophiladiolides, velatumolide and epi-velatumolide, the trihydroxyfuranoeremophilane velatumin, and three eremophilane glucosides were isolated from Pittocaulon velatum, together with several known compounds. The structures of these compounds were elucidated by spectroscopic analysis and chemical reactions. The anti-inflammatory activity of the isolated compounds was investigated using the TPA-induced ear edema model.
authors.affiliation: Instituto de Química, Universidad Nacional Autónoma de México , Circuito Exterior, Ciudad Universitaria, Coyoacán 04510, D.F. México.
authors.forename: Amira
authors.initials: A
authors.lastname: Arciniegas
authors.forename: Karina
authors.initials: K
authors.lastname: González
authors.forename: Ana-L
authors.initials: AL
authors.lastname: Pérez-Castorena
authors.forename: Jhon
authors.initials: J
authors.lastname: Maldonado
authors.forename: José Luis
authors.initials: JL
authors.lastname: Villaseñor
authors.forename: Alfonso Romo
authors.initials: AR
authors.lastname: de Vivar
mesh_terms: D000818:Animals; D000893:Anti-Inflammatory Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D019659:Asteraceae / Q000737:chemistry*; D004195:Disease Models, Animal; D004487:Edema / Q000139:chemically induced / Q000188:drug therapy; D005419:Flavonoids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D005960:Glucosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D008800:Mexico; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D013755:Tetradecanoylphorbol Acetate / Q000494:pharmacology
chemical_list: D000893:Anti-Inflammatory Agents; D005419:Flavonoids; D005960:Glucosides; D012717:Sesquiterpenes; D013755:Tetradecanoylphorbol Acetate