title: Surgical pathology of joint prostheses.
abstract: Joint arthroplasty is a commonly performed surgical procedure that provides significant benefit to the patient. The prosthetic devices are composed of combinations of polyethylene, ceramics, metal alloys, bone cement, and silicone and are associated with complications as well as eventual failure from wear and corrosion. The pathologic findings of these processes are complex and require accurate interpretation to help guide therapy and identify the underlying biological mechanisms.
authors.affiliation: Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA. arosenberg@partners.org
authors.forename: Andrew E
authors.initials: AE
authors.lastname: Rosenberg
authors.forename: G Petur
authors.initials: GP
authors.lastname: Nielsen
authors.forename: John
authors.initials: J
authors.lastname: Reith
mesh_terms: D019643:Arthroplasty, Replacement / Q000009:adverse effects*; D006801:Humans; D007431:Intraoperative Complications; D010340:Pathology, Surgical / Q000379:methods*; D011474:Prosthesis Design; D011475:Prosthesis Failure / Q000209:etiology*; D012509:Sarcoma / Q000209:etiology / Q000473:pathology