title: Endosonographic evaluation of patients with suspected extraluminal compression or subepithelial lesions during upper gastrointestinal endoscopy.
abstract: BACKGROUND
  The aim of this study was to evaluate the endosonographic ultrasound (EUS) findings of patients with suspected extraluminal compression or subepithelial intramural lesions observed during upper gastrointestinal endoscopy.
  
  
  METHODS
  EUS findings were grouped as follows; compression by an extramural pathologic lesion, compression by an adjacent vascular structure, compression by adjacent organs, subepithelial intramural lesion, and normal EUS.
  
  
  RESULTS
  The data of 211 patients referred to the EUS unit between February 2004 and January 2010 for further evaluation of suspected extraluminal compression or subepithelial intramural lesions after upper gastrointestinal endoscopy were retrospectively analyzed. Mean age of the patients was 51.0±15.2 years, 124 (58.9%) of which were female. EUS examination was normal in 48 (22.7%) patients. EUS confirmed the presence of a pathological finding in the esophagus in 38 (92.6%) out of 41 patients when compared with abnormal findings in 122 (73.4%) of 166 patients who were evaluated for suspected lesions of the stomach (P=0.009). Suspected extraluminal compression of the esophagus (n=41) was due to a vascular structure in 17 (41.4% ) patients, an adjacent organ in four (9.7%) patients, an extramural pathological lesion in two (4.9%) patients, and a subepithelial intramural lesions in 15 (36.6%) patients, whereas in three patients (7.4%) EUS findings were normal. Of the 166 patients referred for evaluation of gastric lesions EUS findings were normal in 44 (26.5%) patients, whereas compression due to an adjacent organ was observed in 66 (39.7%) patients followed by compression by an adjacent vascular structure in 34 (20.4%) patients. An extramural pathologic lesion was discovered in 14 (8.6%) patients, whereas suspected compression was due to a subepithelial intramural lesion in eight (4.8%) patients.
  
  
  CONCLUSIONS
  Accurate diagnosis of suspected extraluminal compression or subepithelial intramural lesions, particularly in the stomach, requires meticulous evaluation. EUS provides an invasive but effective option. In one-third of cases, suspected extraluminal compression of the esophagus is actually due to a subepithelial intramural lesion.
authors.affiliation: Department of Gastroenterology, Turkiye Yuksek Ihtisas Teaching and Research Hospital, Ankara, Turkey. erkinous@yahoo.com
authors.forename: Erkin
authors.initials: E
authors.lastname: Oztas
authors.forename: Dilek
authors.initials: D
authors.lastname: Oguz
authors.forename: Mevlut
authors.initials: M
authors.lastname: Kurt
authors.forename: Digdem Ozer
authors.initials: DO
authors.lastname: Etik
authors.forename: Bahattin
authors.initials: B
authors.lastname: Cicek
authors.forename: Murat
authors.initials: M
authors.lastname: Kekilli
authors.forename: Ibrahim Koral
authors.initials: IK
authors.lastname: Onal
authors.forename: Abdurrahim
authors.initials: A
authors.lastname: Sayilir
authors.forename: Sabite
authors.initials: S
authors.lastname: Kacar
authors.forename: Burhan
authors.initials: B
authors.lastname: Sahin
mesh_terms: D000328:Adult; D000368:Aged; D019160:Endosonography; D005260:Female; D005767:Gastrointestinal Diseases / Q000000981:diagnostic imaging*; D005773:Gastroscopy; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies