title: Primary cutaneous actinomycosis caused by Actinomyces bovis in a patient with common variable immunodeficiency.
abstract: Actinomycosis is a chronic, suppurative granulomatous disease caused by the genus Actinomyces. This report is an interesting case of primary cutaneous actinomycosis (PCA) in a patient with common variable immunodeficiency (CVI) affecting the fingernails. The patient was successfully treated with penicillin G, cefazolin and metronidazole as well as surgical debridement of the infected tissues. In a 4-year follow-up period, no recurrence was observed. Primary cutaneous actinomycosis is a rare disease and the diagnosis needs a high index of clinical suspicion with attention to the history of skin implantation of the organism.
authors.affiliation: Department of Dermatology, Imam Hospital, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Parvin
authors.initials: P
authors.lastname: Mansouri
authors.forename: Susan
authors.initials: S
authors.lastname: Farshi
authors.forename: Alireza
authors.initials: A
authors.lastname: Khosravi
authors.forename: Zahra Safaie
authors.initials: ZS
authors.lastname: Naraghi
mesh_terms: D000196:Actinomycosis / Q000175:diagnosis / Q000209:etiology* / Q000382:microbiology / Q000628:therapy; D000293:Adolescent; D017074:Common Variable Immunodeficiency / Q000150:complications*; D006801:Humans; D008297:Male; D017192:Skin Diseases, Bacterial / Q000175:diagnosis / Q000209:etiology* / Q000382:microbiology / Q000628:therapy