title: Antifungal susceptibilities of Sporothrix albicans, S. brasiliensis, and S. luriei of the S. schenckii complex identified in Brazil.
abstract: We studied 40 strains of the species complex formerly classified as the single species Sporothrix schenckii to identify new species within this complex and evaluate their antifungal susceptibility profiles. Based on phenotypic tests (ability to grow at 37°C, colony diameters, and pigmentation of the colonies, as well as assimilation of sucrose and raffinose) and molecular assays (amplification of a fragment of the calmodulin gene), here we report the identification of S. albicans, S. brasiliensis, S. luriei, and S. schenckii; two isolates of these species were detected as itraconazole-resistant strains.
authors.affiliation: Department of Microbiology and Parasitology, Universidade Federal de Santa Maria (UFSM), Santa Maria, Santa Maria 97010-033, Brazil.
authors.forename: Daniele C
authors.initials: DC
authors.lastname: Oliveira
authors.forename: Paulo G Markus
authors.initials: PG
authors.lastname: Lopes
authors.forename: Tatiana B
authors.initials: TB
authors.lastname: Spader
authors.forename: Camila D
authors.initials: CD
authors.lastname: Mahl
authors.forename: Giordano R
authors.initials: GR
authors.lastname: Tronco-Alves
authors.forename: Valeria M
authors.initials: VM
authors.lastname: Lara
authors.forename: Janio M
authors.initials: JM
authors.lastname: Santurio
authors.forename: Sydney Hartz
authors.initials: SH
authors.lastname: Alves
mesh_terms: D000818:Animals; D000935:Antifungal Agents / Q000494:pharmacology*; D001938:Brazil; D016000:Cluster Analysis; D004271:DNA, Fungal / Q000737:chemistry / Q000235:genetics; D006801:Humans; D008826:Microbial Sensitivity Tests; D008969:Molecular Sequence Data; D010802:Phylogeny; D017422:Sequence Analysis, DNA; D013175:Sporothrix / Q000145:classification / Q000187:drug effects* / Q000235:genetics / Q000302:isolation & purification; D013174:Sporotrichosis / Q000382:microbiology* / Q000662:veterinary*
chemical_list: D000935:Antifungal Agents; D004271:DNA, Fungal