title: Age-related androgen deficiency and type 2 diabetes.
abstract: There is a higher prevalence of low testosterone levels in males with type 2 diabetes compared to those without. Additionally, there is evidence that low testosterone levels may predict the development of type 2 diabetes. Symptoms of hypogonadism include decreased libido, decreased bone mineral density (BMD), and decreased lean muscle mass. The majority of the published cases in men with diabetes were attributed to age-related idiopathic hypogonadotropic hypogonadism. This paper reviews the link between type 2 diabetes and age-related hypogonadism and the treatment options for hypogonadism. Pharmacists who provide care for males with diabetes should be aware of the increased incidence of hypogonadism, know how to screen for it, and be able to recommend appropriate therapy.
authors.affiliation: Department of Pharmacy, Mercer University, Atlanta, GA, USA. ryan_gj@mercer.edu
authors.forename: Gina J
authors.initials: GJ
authors.lastname: Ryan
authors.forename: Lynetta J
authors.initials: LJ
authors.lastname: Jobe
mesh_terms: D000375:Aging / Q000097:blood*; D000728:Androgens / Q000097:blood / Q000172:deficiency*; D000818:Animals; D003924:Diabetes Mellitus, Type 2 / Q000097:blood* / Q000188:drug therapy; D020249:Hormone Replacement Therapy / Q000379:methods; D006801:Humans; D007006:Hypogonadism / Q000097:blood* / Q000188:drug therapy; D008297:Male; D013739:Testosterone / Q000097:blood / Q000627:therapeutic use
chemical_list: D000728:Androgens; D013739:Testosterone