title: Vascular effects of exercise: endothelial adaptations beyond active muscle beds.
abstract: Endothelial adaptations to exercise training are not exclusively conferred within the active muscle beds. Herein, we summarize key studies that have evaluated the impact of chronic exercise on the endothelium of vasculatures perfusing nonworking skeletal muscle, brain, viscera, and skin, concluding with discussion of potential mechanisms driving these endothelial adaptations.
authors.affiliation: Biomedical Sciences, University of Missouri, Columbia, Missouri, USA. laughlinM@missouri.edu
authors.forename: Jaume
authors.initials: J
authors.lastname: Padilla
authors.forename: Grant H
authors.initials: GH
authors.lastname: Simmons
authors.forename: Shawn B
authors.initials: SB
authors.lastname: Bender
authors.forename: Arturo A
authors.initials: AA
authors.lastname: Arce-Esquivel
authors.forename: Jeffrey J
authors.initials: JJ
authors.lastname: Whyte
authors.forename: M Harold
authors.initials: MH
authors.lastname: Laughlin
mesh_terms: D000222:Adaptation, Physiological; D000818:Animals; D002560:Cerebrovascular Circulation; D004730:Endothelium, Vascular / Q000502:physiology*; D015444:Exercise; D006439:Hemodynamics; D006801:Humans; D009119:Muscle Contraction; D018482:Muscle, Skeletal / Q000098:blood supply*; D012079:Renal Circulation; D015398:Signal Transduction; D012867:Skin / Q000098:blood supply; D013152:Splanchnic Circulation