title: Relationship between alcohol consumption and clinical manifestation of patients with fatty liver: a single-center study.
abstract: BACKGROUND
  Fatty liver is a common chronic liver disease worldwide. It is associated with an increasing morbidity in China in recent years. The aim of this study was to analyze the effect of drinking alcohol on the hemoglobin and biochemical values of patients with fatty liver.
  
  
  METHODS
  We investigated the clinical and laboratory data of 669 patients with fatty liver. Of the 669 patients, 166 consumed alcohol more than 60 g per week for at least 2 years, and 503 did not have a history of long-term alcohol consumption. We further analyzed the relationship between alcohol consumption and clinical characteristics of these patients.
  
  
  RESULTS
  The values of aspartate transaminase (AST), gamma-glutamyl transpeptidase (GGT), and hemoglobin in the long-term consumption group were significantly higher than those in the non long-term consumption group (P<0.05). In the patients without long-term alcohol consumption, the values of GGT and hemoglobin in patients with light alcohol consumption were significantly higher than those in non alcohol consumers (P<0.05).
  
  
  CONCLUSIONS
  Alcohol consumption is associated with significantly increased values of AST, GGT, and hemoglobin in patients with fatty liver, suggesting their potential roles in hepatic steatosis.
authors.affiliation: International Health Care Center, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China. wanqi1001@163.com
authors.forename: Xiu-Fang
authors.initials: XF
authors.lastname: Wang
authors.forename: Min
authors.initials: M
authors.lastname: Yue
mesh_terms: D000328:Adult; D000368:Aged; D000428:Alcohol Drinking / Q000009:adverse effects*; D001219:Aspartate Aminotransferases / Q000097:blood*; D015415:Biomarkers / Q000097:blood; D016009:Chi-Square Distribution; D002681:China; D004796:Clinical Enzyme Tests; D005234:Fatty Liver / Q000097:blood / Q000175:diagnosis*; D005235:Fatty Liver, Alcoholic / Q000097:blood / Q000175:diagnosis* / Q000209:etiology; D005260:Female; D006454:Hemoglobins / Q000378:metabolism*; D006801:Humans; D008297:Male; D008875:Middle Aged; D065626:Non-alcoholic Fatty Liver Disease; D011237:Predictive Value of Tests; D011379:Prognosis; D018570:Risk Assessment; D012307:Risk Factors; D013997:Time Factors; D015854:Up-Regulation; D005723:gamma-Glutamyltransferase / Q000097:blood*
chemical_list: D015415:Biomarkers; D006454:Hemoglobins; D005723:gamma-Glutamyltransferase; D001219:Aspartate Aminotransferases