title: Antioxidant activity of the giant jellyfish Nemopilema nomurai measured by the oxygen radical absorbance capacity and hydroxyl radical averting capacity methods.
abstract: The giant jellyfish Nemopilema nomurai (reaching sizes of up to 2 m diameter and 150 kg), which forms dense blooms, has caused extensive damage to fisheries by overloading trawl nets, while its toxic nematocysts cause dermatological symptoms. Giant jellyfish are currently discarded on the grounds of pest control. However, the giant jellyfish is considered to be edible and is part of Chinese cuisine. Therefore, we investigated whether any benefits for human health may be derived from consumption of the jellyfish in order to formulate medicated diets. Antioxidant activity of Nemopilema nomurai was measured using the oxygen radical absorbance capacity (ORAC) and hydroxyl radical averting capacity (HORAC) methods. Based on the results, the ORAC value of the giant jellyfish freeze-dried sample was 541 µmol trolox equivalent (TE)/100 g and the HORAC value was 3,687 µmol gallic acid equivalent (GAE)/100 g. On the other hand, the IC50 value of hydroxyl radical scavenging activity measured by using the electron spin resonance method was 3.3%. In conclusion, the results suggest that the freeze-dried powder of the giant jellyfish Nemopilema nomurai is a potentially beneficial food for humans.
authors.affiliation: Course of Resource Management and Food Science, Graduate School of Fisheries Science, National Fisheries University, Independent Administrative Institution, The Ministry of Agriculture Forestry and Fisheries of Japan, Yamaguchi 759-6595, Japan. kazuki@fish-u.ac.jp
authors.forename: Kazuki
authors.initials: K
authors.lastname: Harada
authors.forename: Toshimichi
authors.initials: T
authors.lastname: Maeda
authors.forename: Yoshiro
authors.initials: Y
authors.lastname: Hasegawa
authors.forename: Takushi
authors.initials: T
authors.lastname: Tokunaga
authors.forename: Shinya
authors.initials: S
authors.lastname: Ogawa
authors.forename: Kyoko
authors.initials: K
authors.lastname: Fukuda
authors.forename: Norie
authors.initials: N
authors.lastname: Nagatsuka
authors.forename: Keiko
authors.initials: K
authors.lastname: Nagao
authors.forename: Shunshiro
authors.initials: S
authors.lastname: Ueno
mesh_terms: D000042:Absorption / Q000187:drug effects; D000818:Animals; D000975:Antioxidants / Q000494:pharmacology*; D016166:Free Radical Scavengers / Q000494:pharmacology; D055951:Functional Food; D006801:Humans; D057927:Hydrophobic and Hydrophilic Interactions; D017665:Hydroxyl Radical / Q000737:chemistry / Q000378:metabolism*; D020128:Inhibitory Concentration 50; D010100:Oxygen / Q000378:metabolism*; D037401:Scyphozoa / Q000737:chemistry*
chemical_list: D000975:Antioxidants; D016166:Free Radical Scavengers; D017665:Hydroxyl Radical; D010100:Oxygen