title: The influence of thyroid function on cognition in a sample of ethnically diverse, rural-dwelling women: a project FRONTIER study.
abstract: This study examined the influence of thyroid markers (TSH and FT4) on cognition in a sample of rural-dwelling women. Data were analyzed from 81 women who were enrolled in an ongoing study of rural health, Project FRONTIER. Cognition was assessed with the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS). TSH levels were significantly related to the RBANS Attention Index, and FT4 levels were significantly related to the RBANS Language Index. The current study found that TSH and FT4 were differentially related to neurocognitive domains, with TSH being related only to measures of attention and FT4 to measures of language.
authors.affiliation: Laura W. Bush Institute for Women's Health, Texas Tech University Health Sciences Center, Amarillo; Department of Family and Community Medicine, Texas Tech University Health Sciences Center, Lubbock; Department of Psychology, Texas Tech University, Lubbock, TX, USA.
authors.forename: Leigh A
authors.initials: LA
authors.lastname: Johnson
authors.forename: Valerie
authors.initials: V
authors.lastname: Hobson
authors.forename: Marjorie
authors.initials: M
authors.lastname: Jenkins
authors.forename: Andrew
authors.initials: A
authors.lastname: Dentino
authors.forename: R Michael
authors.initials: RM
authors.lastname: Ragain
authors.forename: Sid
authors.initials: S
authors.lastname: O'Bryant
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001288:Attention / Q000502:physiology*; D003071:Cognition / Q000502:physiology*; D005260:Female; D006801:Humans; D007802:Language; D008568:Memory / Q000502:physiology*; D008875:Middle Aged; D009483:Neuropsychological Tests; D012424:Rural Population; D013972:Thyrotropin / Q000097:blood*; D013974:Thyroxine / Q000097:blood*; D014930:Women
chemical_list: D013972:Thyrotropin; D013974:Thyroxine