title: Recent advances in graphene-based biosensors.
abstract: A detailed overview towards the advancement of graphene based biosensors has been reviewed. The large surface area and excellent electrical conductivity of graphene allow it to act as an "electron wire" between the redox centers of an enzyme or protein and an electrode's surface. Rapid electron transfer facilitates accurate and selective detection of biomolecules. This review discusses the application of graphene for the detection of glucose, Cyt-c, NADH, Hb, cholesterol, AA, UA, DA, and H(2)O(2). GO and RGO have been used for the fabrication of heavy metal ion sensors, gas sensors, and DNA sensors. Graphene based FETs have also been discussed in details. In all these cases, the biosensors performed well with low working potentials, high sensitivities, low detection limits, and long-term stabilities.
authors.affiliation: Department of BIN Fusion Technology, Chonbuk National University, Jeonju, Jeonbuk 561-756, Republic of Korea.
authors.forename: Tapas
authors.initials: T
authors.lastname: Kuila
authors.forename: Saswata
authors.initials: S
authors.lastname: Bose
authors.forename: Partha
authors.initials: P
authors.lastname: Khanra
authors.forename: Ananta Kumar
authors.initials: AK
authors.lastname: Mishra
authors.forename: Nam Hoon
authors.initials: NH
authors.lastname: Kim
authors.forename: Joong Hee
authors.initials: JH
authors.lastname: Lee
mesh_terms: D000818:Animals; D015374:Biosensing Techniques / Q000379:methods* / Q000639:trends; D055664:Electrochemical Techniques / Q000379:methods* / Q000639:trends; D006108:Graphite / Q000737:chemistry* / Q000378:metabolism; D006801:Humans
chemical_list: D006108:Graphite