title: Clinical results of boron neutron capture therapy (BNCT) for glioblastoma.
abstract: The purpose of this study was to evaluate the clinical outcome of BSH-based intra-operative BNCT (IO-BNCT) and BSH and BPA-based non-operative BNCT (NO-BNCT). We have treated 23 glioblastoma patients with BNCT without any additional chemotherapy since 1998. The median survival time (MST) of BNCT was 19.5 months, and 2-year, 3-year and 5-year survival rates were 26.1%, 17.4% and 5.8%, respectively. This clinical result of BNCT in patients with GBM is superior to that of single treatment of conventional radiotherapy compared with historical data of conventional treatment.
authors.affiliation: Department of Neurosurgery, Kagawa National Children's Hospital, Kagawa, Japan. kageji@clin.med.tokushima-u.ac.jp
authors.forename: T
authors.initials: T
authors.lastname: Kageji
authors.forename: Y
authors.initials: Y
authors.lastname: Mizobuchi
authors.forename: S
authors.initials: S
authors.lastname: Nagahiro
authors.forename: Y
authors.initials: Y
authors.lastname: Nakagawa
authors.forename: H
authors.initials: H
authors.lastname: Kumada
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D016754:Boron Neutron Capture Therapy; D001932:Brain Neoplasms / Q000532:radiotherapy*; D005909:Glioblastoma / Q000532:radiotherapy*; D006801:Humans; D008875:Middle Aged; D016019:Survival Analysis; D055815:Young Adult