title: Bisphenol-A and phthalates contamination of urine samples by catheters in the Elfe pilot study: implications for large-scale biomonitoring studies.
abstract: Exposure to phthalates and Bisphenol A could cause developmental and reproductive toxicity. This study provides a first assessment of these exposures for more than 250 French pregnant women. The median concentrations of total and free Bisphenol A in urine were similar to those in other studies except the highest concentrations (5% of women had total and free Bisphenol A >50μg/L). Our study highlights high levels of Di-(2-ethylhexyl)-phthalate metabolites in pregnant women, suggesting recent exposure, probably in hospital. Differences between types of delivery (caesarean vs. natural) support this hypothesis. This is a significant implication for large-scale biomonitoring studies among this population.
authors.affiliation: National Institute of Public Health Surveillance (InVS), Saint Maurice, France. s.vandentorren@invs.sante.fr
authors.forename: Stephanie
authors.initials: S
authors.lastname: Vandentorren
authors.forename: Florence
authors.initials: F
authors.lastname: Zeman
authors.forename: Lise
authors.initials: L
authors.lastname: Morin
authors.forename: Hélène
authors.initials: H
authors.lastname: Sarter
authors.forename: Marie-Laure
authors.initials: ML
authors.lastname: Bidondo
authors.forename: Amivi
authors.initials: A
authors.lastname: Oleko
authors.forename: Henri
authors.initials: H
authors.lastname: Leridon
mesh_terms: D001559:Benzhydryl Compounds; D057785:Catheters; D004784:Environmental Monitoring / Q000379:methods*; D004785:Environmental Pollutants / Q000652:urine*; D005260:Female; D005602:France; D006801:Humans; D010636:Phenols / Q000652:urine*; D010795:Phthalic Acids / Q000652:urine*; D010865:Pilot Projects; D011247:Pregnancy; D014556:Urine / Q000737:chemistry*; D000098826:Bisphenol A Compounds
chemical_list: D001559:Benzhydryl Compounds; D004785:Environmental Pollutants; D010636:Phenols; D010795:Phthalic Acids; C032279:phthalic acid; C006780:bisphenol A; D000098826:Bisphenol A Compounds