title: Efficient synthesis of 4,7-diamino substituted 1,10-phenanthroline-2,9-dicarboxamides.
abstract: A convenient and high-yielding multigram synthesis of the versatile intermediate 4,7-dichloro-1,10-phenanthroline-2,9-dicarboxylic acid is described. The intermediate is further efficiently derivatized to 4,7-diamino-1,10-phenanthroline-2,9-dicarboxamides with potential G-quadruplex stabilizing effects.
authors.affiliation: Department of Physics and Chemistry, University of Southern Denmark, Campusvej 55, DK-5230 Odense M, Denmark.
authors.forename: Anders Foller
authors.initials: AF
authors.lastname: Larsen
authors.forename: Trond
authors.initials: T
authors.lastname: Ulven