title: Clinical characteristics and outcomes of hospitalized patients with 2009 H1N1 influenza in a large acute care tertiary hospital, Singapore.
abstract: This study describes the clinical characteristics and outcomes of hospitalized patients with 2009 H1N1 influenza in a large, acute care, tertiary hospital in Singapore. Of the 265 hospitalized patients with laboratory-confirmed 2009 influenza A (H1N1) during the height of the H1N1 flu pandemic, 13% (35) suffered severe outcomes including a mortality rate of 4.5% (12). Severe outcomes were associated with patients aged 40 years or more, underlying comorbidities, and complicated by pneumonia.
authors.affiliation: Department of Epidemiology, Singapore General Hospital, Road, Singapore 169608. Electronic address: hsann.yin.maw@sgh.com.sg.
authors.forename: Yin Maw
authors.initials: YM
authors.lastname: Hsann
authors.affiliation: Department of Epidemiology, Singapore General Hospital, Road, Singapore 169608.
authors.forename: Sue Ping
authors.initials: SP
authors.lastname: Thang
authors.affiliation: Department of Epidemiology, Singapore General Hospital, Road, Singapore 169608.
authors.forename: Zakir-Hussain
authors.initials: ZH
authors.lastname: Abdul Salam
authors.affiliation: Department of Epidemiology, Singapore General Hospital, Road, Singapore 169608.
authors.forename: Yong
authors.initials: Y
authors.lastname: Yang
authors.affiliation: Department of Epidemiology, Singapore General Hospital, Road, Singapore 169608.
authors.forename: Vincent
authors.initials: V
authors.lastname: Sui-Leong Lim
authors.affiliation: Department of Epidemiology, Singapore General Hospital, Road, Singapore 169608.
authors.forename: Kok Soong
authors.initials: KS
authors.lastname: Yang
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015897:Comorbidity; D004196:Disease Outbreaks; D005260:Female; D017052:Hospital Mortality; D006760:Hospitalization / Q000706:statistics & numerical data*; D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype / Q000302:isolation & purification*; D007251:Influenza, Human / Q000150:complications* / Q000453:epidemiology / Q000401:mortality*; D008297:Male; D008875:Middle Aged; D058873:Pandemics; D011024:Pneumonia, Viral / Q000150:complications / Q000453:epidemiology / Q000209:etiology*; D012720:Severity of Illness Index; D012846:Singapore / Q000453:epidemiology; D055815:Young Adult