title: Progress in the research of Radix Astragali in treating chronic heart failure: effective ingredients, dose-effect relationship and adverse reaction.
abstract: Radix Astragali, a Chinese herbal medicine possessing important cardiovascular pharmacologic effects, is widely applied for the treatment of chronic heart failure (CHF) in clinical practice. This paper summarizes briefly the researches in the last 10 years on its chemical compositions, effective ingredients for improving cardiac function, dose-effect relationship in treating CHF, and adverse reactions that occurred in clinical practice.
authors.affiliation: Department of Cardiovascular Diseases, Wuxi Municipal Hospital of Traditional Chinese Medicien, Wuxi City, Jiangsu Province, China.
authors.forename: Shu
authors.initials: S
authors.lastname: Lu
authors.forename: Ke-ji
authors.initials: KJ
authors.lastname: Chen
authors.forename: Qing-you
authors.initials: QY
authors.lastname: Yang
authors.forename: Hui-ru
authors.initials: HR
authors.lastname: Sun
mesh_terms: D027883:Astragalus Plant / Q000737:chemistry*; D004305:Dose-Response Relationship, Drug; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use*; D006333:Heart Failure / Q000188:drug therapy*; D006801:Humans; D008517:Phytotherapy / Q000639:trends*; D012106:Research / Q000639:trends*
chemical_list: D004365:Drugs, Chinese Herbal