title: Classification of hand eczema: clinical and aetiological types. Based on the guideline of the Danish Contact Dermatitis Group.
abstract: BACKGROUND
  No generally accepted classification scheme for hand eczema exists. The Danish Contact Dermatitis Group recently developed a guideline defining common clinical types and providing criteria for aetiological types.
  
  
  OBJECTIVE
  To test the concepts of this guideline in a group of hand eczema patients.
  
  
  METHODS
  Seven hundred and ten hand eczema patients were included from seven dermatology clinics in Denmark. The hand eczema was classified into one of five clinical types, with standard photographs as reference. The severity was scored by the physician, who also made a final aetiological diagnosis.
  
  
  RESULTS
  Irritant contact dermatitis was most frequent in chronic, dry fissured hand eczema (44.3%), pulpitis (41.7%), and nummular hand eczema (40.9%), whereas allergic contact dermatitis dominated in vesicular types of hand eczema, with recurrent (35%) and few (24.2%) eruptions. Hyperkeratotic palmar hand eczema was the only clinical type that constituted a distinct subgroup; it was found most frequently in older men and had the strongest relationship, although not significant, with non-specific dermatitis.
  
  
  CONCLUSIONS
  The relationship between clinical type of hand eczema and aetiological diagnosis fitted with general experience, but no simple relationship was found. This emphasizes that patch testing and exposure analysis are mandatory. Hyperkeratotic palmar hand eczema was identified as a distinct clinical subtype.
authors.affiliation: Department of Dermato-Allergology, National Allergy Research Centre, Copenhagen University Gentofte Hospital, 2900 Hellerup, Denmark. jedu@geh.regionh.dk
authors.forename: Jeanne Duus
authors.initials: JD
authors.lastname: Johansen
authors.forename: Marianne
authors.initials: M
authors.lastname: Hald
authors.forename: Bo Lasthein
authors.initials: BL
authors.lastname: Andersen
authors.forename: Grete
authors.initials: G
authors.lastname: Laurberg
authors.forename: Anne
authors.initials: A
authors.lastname: Danielsen
authors.forename: Christian
authors.initials: C
authors.lastname: Avnstorp
authors.forename: Berit
authors.initials: B
authors.lastname: Kristensen
authors.forename: Ove
authors.initials: O
authors.lastname: Kristensen
authors.forename: Knud
authors.initials: K
authors.lastname: Kaaber
authors.forename: Jens
authors.initials: J
authors.lastname: Thormann
authors.forename: Torkil
authors.initials: T
authors.lastname: Menné
authors.forename: Niels
authors.initials: N
authors.lastname: Veien
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003430:Cross-Sectional Studies; D003718:Denmark; D017449:Dermatitis, Allergic Contact / Q000175:diagnosis; D017453:Dermatitis, Irritant / Q000175:diagnosis; D004485:Eczema / Q000145:classification* / Q000175:diagnosis / Q000209:etiology; D005260:Female; D006229:Hand Dermatoses / Q000145:classification* / Q000175:diagnosis / Q000209:etiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010328:Patch Tests; D017410:Practice Guidelines as Topic; D011788:Quality of Life; D012720:Severity of Illness Index; D012737:Sex Factors; D055815:Young Adult