title: Idiopathic dural optic nerve sheath calcification associated with choroidal osteoma.
abstract: A 28-year-old woman presented with a choroidal osteoma in the right eye and optic atrophy in the left eye, associated with bilateral optic nerve sheath calcification and calcifications in the pineal, choroid plexus, and dura (falx and tentorium). Visual acuity, tumor size, and intracranial calcifications did not change over 16 years. The combination of bilateral optic nerve sheath calcification with multiple intracranial calcifications suggests an unexplained and generalized dural calcification process. To the authors' knowledge, this is the first case of choroidal ossifying tumor associated with calcified lesions of the optic nerves. Although the pathogenesis of bone formation in choroidal osteoma remains uncertain, intraocular inflammation might be one cause.
authors.affiliation: Department of Ophthalmology, Lozano Blesa University Clinic Hospital, Zaragoza, Spain. jascaso@gmail.com
authors.forename: Francisco J
authors.initials: FJ
authors.lastname: Ascaso
authors.forename: Rafael
authors.initials: R
authors.lastname: Lasierra
mesh_terms: D000328:Adult; D002114:Calcinosis / Q000150:complications* / Q000175:diagnosis; D002493:Central Nervous System Diseases / Q000150:complications* / Q000175:diagnosis; D002830:Choroid Neoplasms / Q000150:complications* / Q000175:diagnosis; D004388:Dura Mater; D005260:Female; D005654:Fundus Oculi; D006801:Humans; D009896:Optic Atrophy / Q000150:complications / Q000175:diagnosis; D009901:Optic Nerve Diseases / Q000150:complications* / Q000175:diagnosis; D010016:Osteoma / Q000150:complications* / Q000175:diagnosis; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography