title: Modulating the acidity: highly acidic Brønsted acids in asymmetric catalysis.
abstract: Recently, chiral highly acidic Brønsted acids have emerged as powerful catalysts for enantioselective C-C and C-X bond-forming reactions. Their strong acidity renders them valuable tools for the activation of imines, carbonyl compounds, and other weakly basic substrates. As a result, new perspectives are opened and highly stereoselective transformations based on the concept of chiral contact-ion-pair catalysis can be realized. This Minireview gives an overview of the design and application of these new organocatalysts and presents recent results in this rapidly growing field.
authors.affiliation: Institut für Organische Chemie, RWTH Aachen, Landoltweg 1, 52074 Aachen, Germany. magnus.rueping@rwth-aachen.de
authors.forename: Magnus
authors.initials: M
authors.lastname: Rueping
authors.forename: Boris J
authors.initials: BJ
authors.lastname: Nachtsheim
authors.forename: Winai
authors.initials: W
authors.lastname: Ieawsuwan
authors.forename: Iuliana
authors.initials: I
authors.lastname: Atodiresei