title: A fibrin adhesive sealing method for the prevention of pancreatic fistula following distal pancreatectomy.
abstract: OBJECTIVE
  Pancreatic fistula is the most common complication following distal pancreatectomy. We have developed a fibrin adhesive sealing method which covers the cut surface and parenchyma of the pancreas, to prevent pancreatic fistula.
  
  
  METHODS
  We performed 25 distal pancreatectomies. Fibrin adhesive (TachoComb) was applied to the staple line of the pancreas before stapling. Pancreatic fistula was defined and graded according to the International Study Group of Postoperative Pancreatic Fistula (ISGPF) definition.
  
  
  RESULTS
  The overall incidence of pancreatic fistula was five cases (20%). Four cases (16%) were classified as Grade A. Only one case (4%) was classified as Grade B. In patients with or without pancreatic fistula, the mean length of postoperative hospital stay was not significant.
  
  
  CONCLUSIONS
  The fibrin adhesive sealing method is a simple and effective method of preventing postoperative pancreatic fistula formation after distal pancreatectomy.
authors.affiliation: Department of Surgery, Shin-Tokyo Hospital, Chiba, Japan. k-mita@sth-medical.co.jp
authors.forename: Kazuhito
authors.initials: K
authors.lastname: Mita
authors.forename: Hideto
authors.initials: H
authors.lastname: Ito
authors.forename: Masato
authors.initials: M
authors.lastname: Fukumoto
authors.forename: Ryo
authors.initials: R
authors.lastname: Murabayashi
authors.forename: Kazuya
authors.initials: K
authors.lastname: Koizumi
authors.forename: Takashi
authors.initials: T
authors.lastname: Hayashi
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Kikuchi
authors.forename: Tadashi
authors.initials: T
authors.lastname: Kagaya
mesh_terms: D000368:Aged; D005260:Female; D015718:Fibrin Tissue Adhesive / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010180:Pancreatectomy / Q000009:adverse effects*; D010185:Pancreatic Fistula / Q000517:prevention & control*; D011183:Postoperative Complications / Q000517:prevention & control*
chemical_list: D015718:Fibrin Tissue Adhesive