title: Synchronous Presence of Nasopharyngeal Carcinoma and Marginal Zone (MALT-Type) B-Cell Lymphoma in the Pharynx.
abstract: Synchronous malignancy of squamous cell carcinoma and malignant lymphoma in the head and neck region is extremely rare. Nasopharyngeal carcinoma is a nonlymphomatous, squamous cell carcinoma that occurs in the nasopharyngeal epithelium. Reported herein is a unique case of nasopharyngeal carcinoma occurring simultaneously with MALT-type lymphoma in an 83-year-old woman, who complained of deglutition dysfunction. Endoscopic examination of respective organs revealed a submucosal tumour on the posterior wall of pharynx. Biopsy of the hypopharynx was taken and sent for histological examination, which revealed two different neoplasms. Immunohistochemical and molecular analysis confirmed the diagnosis of nasopharyngeal carcinoma coexisting with a MALT-type lymphoma.
authors.affiliation: Department of Pathology, Medical School, Aristotle University of Thessaloniki, 54009 Thessaloniki, Greece.
authors.forename: Triantafyllia
authors.initials: T
authors.lastname: Koletsa
authors.forename: Georgios
authors.initials: G
authors.lastname: Petrakis
authors.forename: Georgia
authors.initials: G
authors.lastname: Karayannopoulou
authors.forename: Dimitrios
authors.initials: D
authors.lastname: Pappas
authors.forename: Konstantinos
authors.initials: K
authors.lastname: Markou
authors.forename: Georgios
authors.initials: G
authors.lastname: Karkavelas
authors.forename: Ioannis
authors.initials: I
authors.lastname: Kostopoulos