title: Cardiovascular disease risk factors and depression in Korean women: results from the fourth Korean National Health and Nutrition Examination Survey.
abstract: Depression is the fourth leading factor of disease burden for the global female population, but while increasing evidence has supported a contributing role of depression in cardiovascular disease, little is known about this association within the female population of Korea. We examined the association in a study of 5658 Korean women who participated in the fourth Korean National Health and Nutrition Examination Survey. A logistic regression was used to calculate odds ratios (ORs) and 95% confidence intervals (CIs). A total of 279 cases of depression were included. Cardiovascular disease risk factors were associated with higher odds of depression: ORs (95% CIs) were 3.99 (2.25-7.05) for current smokers with <5 pack-years vs. never-smokers, 1.97 (1.18-3.30) for ≥28 vs. <20kg/m(2) of body mass index, 1.42 (1.03-1.95) for 100-125 vs. <100mg/dL of fasting serum glucose levels, and 2.10 (1.46-3.03) for a history of hyperlipidemia. Women with a history of two or three comorbid disorders (diabetes, hypertension, and cardiovascular disease) had a 1.63-fold higher OR for depression than women without any of these diseases. Korean women with depression had a greater prevalence of major risk factors for cardiovascular disease than women without depression.
authors.affiliation: Department of Food and Nutrition, Sookmyung Women's University, Seoul, Republic of Korea.
authors.forename: Jong Eun
authors.initials: JE
authors.lastname: Park
authors.forename: Jung Eun
authors.initials: JE
authors.lastname: Lee
mesh_terms: D000328:Adult; D000368:Aged; D000886:Anthropometry; D015992:Body Mass Index; D002318:Cardiovascular Diseases / Q000453:epidemiology*; D016001:Confidence Intervals; D003863:Depression / Q000453:epidemiology*; D004467:Economics; D005260:Female; D006801:Humans; D008019:Life Style; D016015:Logistic Models; D008875:Middle Aged; D009749:Nutrition Surveys; D016017:Odds Ratio; D056910:Republic of Korea / Q000453:epidemiology; D012307:Risk Factors; D012907:Smoking / Q000453:epidemiology