title: Synthesis of a novel class of cyclodextrin-based nanotubes.
abstract: The synthesis and characterization of a novel class of structurally well-defined nanotubes from β-cyclodextrin are described. These new hosts were formed using disulfide linkages that substitute all the primary hydroxyl groups of a β-cyclodextrin. A deep and rigid hydrophobic channel with a size of more than 1.5 nm is found in the molecules. Because of their unique geometry and the potential biodegradability of the disulfide bond, this class of molecules could find broad applications in biology and other areas of research.
authors.affiliation: Alberta Ingenuity Centre for Carbohydrate Science, Department of Chemistry, University of Calgary, 2500 University Drive NW, Calgary, Alberta T2N 1N4, Canada.
authors.forename: Aixia
authors.initials: A
authors.lastname: Wang
authors.forename: Wenling
authors.initials: W
authors.lastname: Li
authors.forename: Ping
authors.initials: P
authors.lastname: Zhang
authors.forename: Chang-Chun
authors.initials: CC
authors.lastname: Ling
mesh_terms: D008958:Models, Molecular; D015394:Molecular Structure; D043942:Nanotubes; D013237:Stereoisomerism; D013457:Sulfur Compounds / Q000737:chemistry; D047392:beta-Cyclodextrins / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D013457:Sulfur Compounds; D047392:beta-Cyclodextrins