title: Clostridium difficile in children: colonisation and disease.
abstract: Clostridium difficile is the commonest cause of hospital acquired diarrhoea in adults and is associated with significant mortality and morbidity. The clinical significance of C. difficile in children, however, is less certain. In this article we discuss colonisation and infection and describe C. difficile in childhood in terms of risk factors, epidemiology and management.
authors.affiliation: Clinical Microbiology and Public Health Laboratory, Peterborough and Stamford NHS Foundation Trust, Peterborough City Hospital, Bretton Gate, Peterborough, PE3 9GZ, UK.
authors.forename: David A
authors.initials: DA
authors.lastname: Enoch
authors.forename: Matthew J
authors.initials: MJ
authors.lastname: Butler
authors.forename: Sumita
authors.initials: S
authors.lastname: Pai
authors.forename: Sani H
authors.initials: SH
authors.lastname: Aliyu
authors.forename: J Andreas
authors.initials: JA
authors.lastname: Karas
mesh_terms: D000293:Adolescent; D002353:Carrier State / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology* / Q000517:prevention & control; D002648:Child; D002675:Child, Preschool; D016360:Clostridioides difficile / Q000302:isolation & purification*; D003015:Clostridium Infections / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology* / Q000517:prevention & control; D003428:Cross Infection / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology / Q000517:prevention & control; D003967:Diarrhea / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology / Q000517:prevention & control; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D012307:Risk Factors