title: Disseminated intravascular coagulation due to IgM-mediated autoimmune hemolytic anemia.
abstract: Disseminated intravascular coagulation (DIC) due to red cell hemolysis has been previously attributed to transfusion-related hemolytic reactions, but not to autoimmune hemolytic anemia. We report a case of DIC in a child with complement-fixing IgM-mediated cold-agglutinin autoimmune hemolysis, which resulted in arterial thrombosis and gangrene of the upper and lower extremities.
authors.affiliation: Department of Pediatrics, Stanford University School of Medicine, Palo Alto, California, USA.
authors.forename: N Teresa
authors.initials: NT
authors.lastname: Bleakly
authors.forename: Magali J
authors.initials: MJ
authors.lastname: Fontaine
authors.forename: Lisa L
authors.initials: LL
authors.lastname: Pate
authors.forename: Scott M
authors.initials: SM
authors.lastname: Sutherland
authors.forename: Michael
authors.initials: M
authors.lastname: Jeng
mesh_terms: D000744:Anemia, Hemolytic, Autoimmune / Q000150:complications* / Q000276:immunology; D004211:Disseminated Intravascular Coagulation / Q000209:etiology* / Q000276:immunology; D005260:Female; D006801:Humans; D007075:Immunoglobulin M / Q000097:blood*; D007223:Infant
chemical_list: D007075:Immunoglobulin M