title: ROCK-driven actomyosin contractility induces tissue stiffness and tumor growth.
abstract: The tumor environment consists of tumor-associated cells, such as macrophages, fibroblasts, and extracellular matrix, and has an important impact on tumor progression. In this issue of Cancer Cell, Samuel et al. show that ROCK-driven actomyosin contractility increases tissue stiffness affecting epidermal homeostasis, as well as tumor growth and progression.
authors.affiliation: Cancer Research UK, Tumour Cell Signalling Unit, Institute of Cancer Research, London.
authors.forename: Sandra
authors.initials: S
authors.lastname: Kümper
authors.forename: Christopher J
authors.initials: CJ
authors.lastname: Marshall