title: Comparison of the efficacy of articaine and prilocaine local anaesthesia for pulpotomy of maxillary and mandibular primary molars.
abstract: OBJECTIVE
  The aim of this study was to compare the local anaesthetic efficacy of articaine HCl and prilocaine HCl during an operative procedure after their administration by either mandibular nerve block or maxillary infiltration.
  
  
  METHODS
  
  
  
  METHODS
  The study was a double-blind clinical study which comprised 162 children (81 boys and 81 girls), who required a pulpotomy on their primary molars. Pain-related behaviours were used to assess the severity of pain during the injection of either prilocaine HCl or articaine HCl and the operative procedures following either a maxillary infiltration or mandibular nerve block of the two local anaesthetic agents. The frequencies of post-procedural adverse events in the prilocaine and articaine anaesthetised groups were also determined.
  
  
  RESULTS
  Significantly more discomfort (p<0.05) was observed following maxillary infiltration compared to mandibular nerve block. There were no significant differences in the pain-related behaviours scores between the two local anaesthetic agents administered during the dental operative procedures, except for the removal of the coronal pulp. For this latter procedure, the pain-related behaviour score was 1.5- times higher in the prilocain-anaesthetised children than in the articaine-anaesthetised children. The frequencies of post- procedural adverse events in the prilocaine-treated children were similar to those found in the articaine-treated children.
  
  
  CONCLUSIONS
  We concluded that local anaesthesia following mandibular nerve block is more effective than that following maxillary infiltration in 6-8-year-old children. However, the intensity of pain that was experienced by the children during administration of either prilocaine or articaine and some of the dental procedures after their administration were similar.
authors.affiliation: Department of Pedodontics, Faculty of Dentistry, Atatürk University, Erzurum (Turkey). yyilmaz25@gmail.com
authors.forename: Y
authors.initials: Y
authors.lastname: Yilmaz
authors.forename: O
authors.initials: O
authors.lastname: Eyuboglu
authors.forename: S
authors.initials: S
authors.lastname: Keles
mesh_terms: D017607:Aluminum Compounds / Q000627:therapeutic use; D000779:Anesthetics, Local / Q000008:administration & dosage*; D017610:Calcium Compounds / Q000627:therapeutic use; D002126:Calcium Hydroxide / Q000627:therapeutic use; D002355:Carticaine / Q000008:administration & dosage*; D002648:Child; D003738:Dental Cements / Q000627:therapeutic use; D004311:Double-Blind Method; D004338:Drug Combinations; D005260:Female; D005290:Ferric Compounds / Q000627:therapeutic use; D005500:Follow-Up Studies; D005566:Formocresols / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008334:Mandible; D008340:Mandibular Nerve; D008437:Maxilla; D008963:Molar / Q000473:pathology*; D009407:Nerve Block; D010087:Oxides / Q000627:therapeutic use; D010147:Pain Measurement; D011183:Postoperative Complications; D011318:Prilocaine / Q000008:administration & dosage*; D057872:Pulp Capping and Pulpectomy Agents / Q000627:therapeutic use; D011672:Pulpotomy / Q000295:instrumentation / Q000379:methods*; D016733:Rubber Dams; D017640:Silicates / Q000627:therapeutic use; D014094:Tooth, Deciduous / Q000473:pathology*; D016896:Treatment Outcome
chemical_list: D017607:Aluminum Compounds; D000779:Anesthetics, Local; D017610:Calcium Compounds; D003738:Dental Cements; D004338:Drug Combinations; D005290:Ferric Compounds; D005566:Formocresols; D010087:Oxides; D057872:Pulp Capping and Pulpectomy Agents; D017640:Silicates; C086631:mineral trioxide aggregate; D011318:Prilocaine; C031025:formocresol; C024823:ferric sulfate; D002355:Carticaine; D002126:Calcium Hydroxide