title: Two-dimensional speckle-tracking strain imaging in the assessment of mechanical properties of carotid arteries: feasibility and comparison with conventional markers of subclinical atherosclerosis.
abstract: OBJECTIVE
  The aim of our study was to assess the two-dimensional carotid strain as an index of arterial stiffness in a population of patients without carotid atherosclerotic plaques.
  
  
  RESULTS
  Two-dimensional carotid strain, carotid intima-media thickness (CIMT), stiffness index (β), Peterson's elastic modulus, and distensibility coefficient were evaluated in 47 patients. For all patients, cardiovascular risk scores were calculated. Peak systolic circumferential strain was significantly correlated with conventional indices of arterial stiffness and with the CIMT. Peak systolic circumferential strain adjusted for pulse pressure was the only parameter that showed a significant difference between the three cardiovascular risk groups in which patients were classified. Two-dimensional carotid strain showed an excellent reproducibility.
  
  
  CONCLUSIONS
  The two-dimensional strain allows the assessment of carotid arterial mechanics. Probably the assessment of arterial stiffness allows a better risk stratification of patients.
authors.affiliation: Sezione di Diagnostica Cardiovascolare, Istitito Clinico Prof. Dr R. De Blasi, Via Torrione prol.to 55, Reggio Calabria, Italy.
authors.forename: Mariarita
authors.initials: M
authors.lastname: Catalano
authors.forename: Alessandro
authors.initials: A
authors.lastname: Lamberti-Castronuovo
authors.forename: Antonino
authors.initials: A
authors.lastname: Catalano
authors.forename: Domenico
authors.initials: D
authors.lastname: Filocamo
authors.forename: Carmelo
authors.initials: C
authors.lastname: Zimbalatti
mesh_terms: D000328:Adult; D001161:Arteriosclerosis / Q000000981:diagnostic imaging* / Q000473:pathology; D015415:Biomarkers; D002339:Carotid Arteries / Q000000981:diagnostic imaging* / Q000473:pathology; D002340:Carotid Artery Diseases / Q000000981:diagnostic imaging* / Q000473:pathology; D004452:Echocardiography / Q000295:instrumentation*; D005240:Feasibility Studies; D005260:Female; D006305:Health Status Indicators; D006801:Humans; D008297:Male; D008875:Middle Aged; D018570:Risk Assessment / Q000379:methods; D013599:Systole; D017539:Tunica Intima / Q000000981:diagnostic imaging / Q000473:pathology; D017540:Tunica Media / Q000000981:diagnostic imaging / Q000473:pathology
chemical_list: D015415:Biomarkers