title: Solitary rectal ulcer syndrome: exploring possible management options.
abstract: Solitary rectal ulcer syndrome (SRUS) is a rare condition with various causes that results in ischemic injury. The aim of this study was to assess the clinical findings, diagnosis, and outcomes of treatment in patients with SRUS. Between 1992 and 2006, a retrospective review was undertaken for all patients diagnosed with SRUS. Fifty-eight patients were diagnosed with SRUS. Among patients with paradoxic rectal spasm (PRS), lesions disappeared in 1 of 3 given applied biofeedback treatment, and in 2 of 4 injected with Botulinum toxin (Botox). Twenty-three patients underwent appropriate surgical treatment. Overall, postoperative improvement was seen in 18 patients (78.2%). In conclusion, every patient with SRUS must be assessed for causative disease. Treatment should include conservative approaches such as Botox injection; in patients with pelvic floor disorders, surgical treatment should be considered.
authors.affiliation: Department of General Surgery, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.
authors.forename: Turker
authors.initials: T
authors.lastname: Bulut
authors.forename: Emel
authors.initials: E
authors.lastname: Canbay
authors.forename: Sumer
authors.initials: S
authors.lastname: Yamaner
authors.forename: Mine
authors.initials: M
authors.lastname: Gulluoglu
authors.forename: Dursun
authors.initials: D
authors.lastname: Bugra
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001676:Biofeedback, Psychology; D001905:Botulinum Toxins / Q000627:therapeutic use; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D008365:Manometry; D008866:Microsurgery / Q000379:methods; D008875:Middle Aged; D012002:Rectal Diseases / Q000175:diagnosis* / Q000628:therapy*; D012189:Retrospective Studies; D013577:Syndrome; D016896:Treatment Outcome; D014456:Ulcer / Q000175:diagnosis* / Q000628:therapy*
chemical_list: D001905:Botulinum Toxins