title: Allergic diseases, gene-environment interactions.
abstract: Allergic asthma develops in part from dysregulation of the innate and adaptive immune functions, particularly an imbalance in the Th2-driven adaptive immune response. This dysregulation is the result of complex interactions between genes and environment. These interactions occur both pre- and postnatally, providing opportunities for early interventions in immunological programming.
authors.affiliation: Institute of Laboratory Medicine and Pathobiochemistry, Molecular Diagnostics, University Hospital Giessen and Marburg Faculty of Medicine, Philipps University Marburg, Germany. renzh@med.uni-marburg.de
authors.forename: H
authors.initials: H
authors.lastname: Renz
authors.forename: M
authors.initials: M
authors.lastname: Conrad
authors.forename: S
authors.initials: S
authors.lastname: Brand
authors.forename: R
authors.initials: R
authors.lastname: Teich
authors.forename: H
authors.initials: H
authors.lastname: Garn
authors.forename: P I
authors.initials: PI
authors.lastname: Pfefferle
mesh_terms: D000150:Acinetobacter / Q000276:immunology; D000151:Acinetobacter Infections / Q000276:immunology; D000818:Animals; D004777:Environment; D044127:Epigenesis, Genetic; D005260:Female; D005786:Gene Expression Regulation; D006801:Humans; D006967:Hypersensitivity / Q000235:genetics* / Q000276:immunology* / Q000517:prevention & control; D007371:Interferon-gamma / Q000096:biosynthesis / Q000235:genetics / Q000276:immunology; D008431:Maternal-Fetal Exchange / Q000276:immunology; D011247:Pregnancy; D013601:T-Lymphocytes / Q000276:immunology
chemical_list: D007371:Interferon-gamma