title: Depression and reasons for living among AIDS patients: protecting quality of life when the end is in sight.
abstract: BACKGROUND
  Patients with AIDS are at risk for becoming depressed, pessimistic, and may begin to desire to die. The desire to live may remain strong in AIDS patients through the maintenance of physical health and a lack of pain. However, improvement in physical health is not always followed by resurgence in the will to live. Psychological variables may be important for protecting reasons for living in AIDS patients.
  
  
  OBJECTIVE
  The current study was designed to examine protective factors associated with the will to live among AIDS patients, including physical functioning, depression, and quality of life.
  
  
  METHODS
  Sixty-eight AIDS patients participated in the current study during their outpatient visits to an infectious disease unit. Self-report questionnaires were administered to assess depression, quality of life, a variety of physical health variables, and reasons for living.
  
  
  RESULTS
  Analyses revealed that reasons for living reported by AIDS patients were best understood by overall quality of life. Depression was associated with pessimistic beliefs about the medical illness. Depression was not significantly related to physical functioning or role limitations.
  
  
  CONCLUSIONS
  AIDS patients with poor physical functioning may maintain important reasons for living if a high sense of quality of life is achieved. The assessment and treatment of quality of life in AIDS patients should include strategies that foster a sense of achievement, strengthen interpersonal relationships, and increase positive self-expression.
authors.affiliation: Case Western Reserve University, Cleveland, OH 44106-7123, USA.
authors.forename: Abby L
authors.initials: AL
authors.lastname: Braden
authors.forename: James C
authors.initials: JC
authors.lastname: Overholser
authors.forename: Eden
authors.initials: E
authors.lastname: Silverman
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000453:epidemiology / Q000523:psychology*; D000203:Activities of Daily Living / Q000523:psychology; D000328:Adult; D000368:Aged; D001293:Attitude to Death; D015897:Comorbidity; D003866:Depressive Disorder / Q000453:epidemiology / Q000523:psychology*; D005260:Female; D006304:Health Status; D006801:Humans; D007398:Interpersonal Relations; D008297:Male; D008875:Middle Aged; D010146:Pain / Q000150:complications / Q000523:psychology; D011788:Quality of Life / Q000523:psychology*; D057566:Self Report; D012944:Social Support; D011795:Surveys and Questionnaires