title: Spontaneous remission in localized diffuse large B-cell lymphoma.
abstract: Diffuse large B-cell lymphoma (DLBCL) is an aggressive neoplastic disease of the lymphatic system, the activated B-cell type of this disease is likely to have a substantially worse prognosis. In this study, we report the favorable outcome of the activated B-cell type of DLBCL, though untreated, 7 years after diagnosis. In 2003, DLBCL localized to the root of tongue was found in the patient complaining of dysphonia and a pharyngeal globus perception but the patient did not agree to get any active hematological treatment. During the following years, the patient did not have any complaints. At the otorhinolaryngological control examination, in 2010, she was complaint-free, had normal laboratory parameters. Moreover a PET-CT scan did not reveal metabolic activity relating to malignancy. The extraordinary disease process can be explained by the spontaneous regression of the activated B-cell type DLBCL. Spontaneous regression of oral lymphoma has been published only exceptionally. To our knowledge, no report of spontaneous regression of activated B-cell type DLBLC has been reported.
authors.affiliation: Department of Oto-Rhino-Laryngology, Jahn Ferenc Hospital, Budapest, Hungary. tamlaci@freemail.hu
authors.forename: László
authors.initials: L
authors.lastname: Tamás
authors.forename: Eszter
authors.initials: E
authors.lastname: Sári
authors.forename: Gábor
authors.initials: G
authors.lastname: Répássy
authors.forename: Péter
authors.initials: P
authors.lastname: Szabó
authors.forename: Eniko
authors.initials: E
authors.lastname: Bagdi
authors.forename: László
authors.initials: L
authors.lastname: Krenács
authors.forename: Judit
authors.initials: J
authors.lastname: Demeter
mesh_terms: D000368:Aged; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D016403:Lymphoma, Large B-Cell, Diffuse / Q000175:diagnosis*; D009365:Neoplasm Regression, Spontaneous; D049268:Positron-Emission Tomography; D011379:Prognosis; D019275:Radiopharmaceuticals; D012075:Remission, Spontaneous; D014057:Tomography, X-Ray Computed
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18