title: [The results of use of the antiadhesive seprafilm barrier in adhesive disease of abdomen].
abstract: The results of treatment of 16 patients with abdominal adhesive disease are presented. In the surveyed group there were 7 women and 9 men. The average age of patients was 47,7 ± 14,0 (23-71). Mean duration of history of intestinal obstruction were 48,9 ± 31,5 (5-120) hours. 12 patients underwent surgery for acute adhesive small bowel obstruction. In 7 patients obturative and in 5 patients strangulated obstructions were revealed. In 9 patients laparoscopic resolution of obstruction was performed (no cases of conversion), in 3 patients open surgery is done. 4 patients were operated on for abdominal chronic pain, among them in three cases laparoscopy was performed, in one case open adhesiolysis was done. In order to prevent adhesions antiadhesive seprafilm membrane was applied in all patients. During laparoscopy the following technique was used - rolling of the film seprafilm with protective paper wrapper, the introduction into the abdominal cavity, the deployment of the roll, application of film to the anterior abdominal wall and the surfaces of omentum or intestines. No intra- and postoperative complications were observed. During observation no evidence of intestinal obstruction was observed in the operated patients. There was no mortality. The combination of laparoscopic adhesiolysis with antiadhesive barrier seprafilm is one of the best methods of treatment and prevention of adhesive disease of abdomen.
authors.affiliation: Yerevan State Medical University, Chair of Surgery №2, The Ministry of Health of the Republic of Armenia.
authors.forename: S
authors.initials: S
authors.lastname: Stepanian
mesh_terms: D015746:Abdominal Pain / Q000601:surgery; D034861:Abdominal Wall / Q000473:pathology; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D006820:Hyaluronic Acid / Q000627:therapeutic use*; D007415:Intestinal Obstruction / Q000601:surgery*; D010535:Laparoscopy / Q000379:methods; D008297:Male; D008875:Middle Aged; D009852:Omentum / Q000473:pathology; D011183:Postoperative Complications / Q000601:surgery; D012008:Recurrence; D000267:Tissue Adhesions / Q000601:surgery; D016896:Treatment Outcome
chemical_list: C118198:Seprafilm; D006820:Hyaluronic Acid