title: Shorter and modular synthesis of hemicryptophane-tren derivatives.
abstract: Hemicryptophanes are host molecules with many applications as supramolecular catalysts or in ion selective recognition. A very convenient and efficient modular approach for the synthesis of hemicryptophane-tren (tren, tris(2-aminoethyl)-amine) derivatives has been developed. For instance, hemicryptophane 1 was synthesized at the gram scale in four steps from vanillyl alcohol compared to the previous seven-step procedure. The size, shape, and functionalities of the molecular cavity were also easily modified.
authors.affiliation: Laboratoire de Chimie, CNRS, École Normale Supérieure de Lyon, 46 Allée d'Italie, F-69364 Lyon, France.
authors.forename: Bastien
authors.initials: B
authors.lastname: Chatelet
authors.forename: Elina
authors.initials: E
authors.lastname: Payet
authors.forename: Olivier
authors.initials: O
authors.lastname: Perraud
authors.forename: Pascal
authors.initials: P
authors.lastname: Dimitrov-Raytchev
authors.forename: Laure-Lise
authors.initials: LL
authors.lastname: Chapellet
authors.forename: Véronique
authors.initials: V
authors.lastname: Dufaud
authors.forename: Alexandre
authors.initials: A
authors.lastname: Martinez
authors.forename: Jean-Pierre
authors.initials: JP
authors.lastname: Dutasta