title: The value of MDCT in diagnosis of hyaline-vascular Castleman's disease.
abstract: OBJECTIVE
  Castleman's disease (CD) is an uncommon entity characterized by a massive growth of lymphoid tissue. There are two types: the hyaline-vascular (HV) type and the plasma cell (PC) type. The purpose of this study was to evaluate the clinical value of multiple detector computed tomography (MDCT) in the diagnosis and planning of treatment for hyaline-vascular CD.
  
  
  METHODS
  Fifty-two cases of confirmed hyaline-vascular CD were retrospectively reviewed. Unenhanced and contrast-enhanced MDCT scans had been performed in all patients, followed by surgery and pathological analysis of the lesion. Original MDCT transverse and reconstructed images were used for image interpretation. Features of the lesion and its adjacent structures were identified.
  
  
  RESULTS
  The lesion was present in the thorax of 24 patients and the abdomen in 28. Obvious features of hyaline-vascular CD (especially feeding vessels and draining veins) and its adjacent structures were demonstrated on 52 patients.
  
  
  CONCLUSIONS
  On MDCT imaging, original MDCT transverse and reconstructed images provide an excellent tool for diagnosis of hyaline-vascular CD and have high value in the determination of a treatment plan.
authors.affiliation: Department of Radiology, Beijing Shijitan Hospital affiliated to Capital University of Medical Sciences, Yangfangdian Tieyiyuan, Road No. 10, Haidian District, Beijing, 100038 China.
authors.forename: Xiaoli
authors.initials: X
authors.lastname: Sun
authors.forename: Cheng
authors.initials: C
authors.lastname: Liu
authors.forename: Rengui
authors.initials: R
authors.lastname: Wang
authors.forename: Xuejun
authors.initials: X
authors.lastname: Zhu
authors.forename: Li
authors.initials: L
authors.lastname: Gao
authors.forename: Jiuhong
authors.initials: J
authors.lastname: Chen
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D005871:Castleman Disease / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed / Q000379:methods*; D055815:Young Adult