title: Ewing sarcoma/primitive neuroectodermal tumor arising from the adrenal gland in an adolescent.
abstract: We review the case of an adolescent who presented with flank pain, fatigue and a discrete nonfunctioning adrenal lesion which was found to be an adrenal Ewing sarcoma/primitive neuroectodermal tumor (ES/PNET). The patient was treated with a minimally invasive adrenalectomy as a component of multimodal therapy, including seven courses of chemotherapy and whole abdominal radiation. She is currently disease free 14 months after the operation and 3 months off therapy.
authors.affiliation: Division of General and Thoracic Surgery, Seattle Children's Hospital and University of Washington, Seattle, Washington 98105, USA.
authors.forename: Jacob
authors.initials: J
authors.lastname: Stephenson
authors.forename: Kenneth W
authors.initials: KW
authors.lastname: Gow
authors.forename: John
authors.initials: J
authors.lastname: Meehan
authors.forename: Douglas S
authors.initials: DS
authors.lastname: Hawkins
authors.forename: Jeffrey
authors.initials: J
authors.lastname: Avansino
mesh_terms: D000293:Adolescent; D000306:Adrenal Cortex Neoplasms / Q000473:pathology* / Q000628:therapy; D000315:Adrenalectomy; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage; D003131:Combined Modality Therapy; D003520:Cyclophosphamide / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage; D005047:Etoposide / Q000008:administration & dosage; D005260:Female; D006801:Humans; D007069:Ifosfamide / Q000008:administration & dosage; D018241:Neuroectodermal Tumors, Primitive, Peripheral / Q000473:pathology* / Q000628:therapy; D011878:Radiotherapy; D012512:Sarcoma, Ewing / Q000473:pathology* / Q000628:therapy; D014750:Vincristine / Q000008:administration & dosage
chemical_list: D014750:Vincristine; D005047:Etoposide; D004317:Doxorubicin; D003520:Cyclophosphamide; D007069:Ifosfamide