title: Sebaceous adenoma arising within an ovarian mature cystic teratoma in Muir-Torre syndrome.
abstract: This is the first reported case of a sebaceous adenoma arising within an ovarian mature cystic teratoma in a patient with Muir-Torre syndrome. The pathologic findings and a literature review are presented, including the importance and possible benefits of an early diagnosis of Muir-Torre syndrome. It is proposed that the presence of a sebaceous adenoma in an ovarian cystic teratoma may serve as a useful trigger to consider further history and investigations, with the goal of identifying an important genetic cancer predisposition syndrome.
authors.affiliation: Pathology Queensland, Royal Brisbane and Women's Hospital, Herston QLD 4029, Australia. jason_smith@health.qld.gov.au
authors.forename: Jason
authors.initials: J
authors.lastname: Smith
authors.forename: Karen
authors.initials: K
authors.lastname: Crowe
authors.forename: Julie
authors.initials: J
authors.lastname: McGaughran
authors.forename: Thomas
authors.initials: T
authors.lastname: Robertson
mesh_terms: D018266:Adenocarcinoma, Sebaceous / Q000150:complications* / Q000473:pathology / Q000601:surgery; D001706:Biopsy; D003937:Diagnosis, Differential; D005260:Female; D020022:Genetic Predisposition to Disease; D006801:Humans; D008875:Middle Aged; D055653:Muir-Torre Syndrome / Q000150:complications* / Q000473:pathology / Q000601:surgery; D051718:MutS Homolog 2 Protein / Q000235:genetics; D009154:Mutation; D010048:Ovarian Cysts / Q000150:complications* / Q000473:pathology / Q000601:surgery; D010051:Ovarian Neoplasms / Q000150:complications* / Q000473:pathology / Q000601:surgery; D013724:Teratoma / Q000150:complications* / Q000473:pathology / Q000601:surgery
chemical_list: C497172:MSH2 protein, human; D051718:MutS Homolog 2 Protein