title: Caffeic Acid, a versatile pharmacophore: an overview.
abstract: The caffeic acid scaffold, which is abundant in nature, is extremely versatile and is found in a number of biologically active molecules. The purpose of this review is to provide an overview of the pharmacological activity of synthetic caffeic acid analogs including recent reports of anti-inflammatory, anti-cancer, and antiviral activities of these compounds.
authors.affiliation: Department of Chemistry and Biochemistry, Université de Moncton, Canada. mohamed.touaibia@umoncton.ca
authors.forename: M
authors.initials: M
authors.lastname: Touaibia
authors.forename: J
authors.initials: J
authors.lastname: Jean-François
authors.forename: J
authors.initials: J
authors.lastname: Doiron
mesh_terms: D019380:Anti-HIV Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D000893:Anti-Inflammatory Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D000970:Antineoplastic Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000633:toxicity; D000975:Antioxidants / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D002109:Caffeic Acids / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D006801:Humans
chemical_list: D019380:Anti-HIV Agents; D000893:Anti-Inflammatory Agents; D000970:Antineoplastic Agents; D000975:Antioxidants; D002109:Caffeic Acids; C040048:caffeic acid