title: Adopting extensive intra-operative peritoneal lavage (EIPL) as the standard prophylactic strategy for peritoneal recurrence.
abstract: EIPL (extensive intra-operative peritoneal lavage) therapy was developed as a prophylactic strategy for peritoneal recurrence, with the goal of improving the quality of life and survival span for advanced gastric cancer patients with peritoneal free cancer cells. The purpose of this article is to review the therapy's contribution to a remarkable improvement in the 5-year survival for patients with positive lavage cytology on prospective randomized controlled clinical trials. We also advocate for the adoption of the EIPL as the optimal treatment protocol for advanced gastric cancer.
authors.affiliation: Department of Surgery, Yatsushiro Social Insurance General Hospital, Japan. shimadas@yatsushiro-gh.jp
authors.forename: Shinya
authors.initials: S
authors.lastname: Shimada
authors.forename: Masafumi
authors.initials: M
authors.lastname: Kuramoto
authors.forename: Takashi
authors.initials: T
authors.lastname: Marutsuka
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Yagi
authors.forename: Hideo
authors.initials: H
authors.lastname: Baba
mesh_terms: D002272:Carcinoembryonic Antigen / Q000235:genetics; D017024:Chemotherapy, Adjuvant; D006801:Humans; D053554:Keratin-20 / Q000235:genetics; D009364:Neoplasm Recurrence, Local / Q000517:prevention & control; D010533:Peritoneal Lavage; D010534:Peritoneal Neoplasms / Q000517:prevention & control*; D010537:Peritoneum / Q000166:cytology; D012333:RNA, Messenger / Q000032:analysis; D016032:Randomized Controlled Trials as Topic; D020133:Reverse Transcriptase Polymerase Chain Reaction; D013274:Stomach Neoplasms / Q000473:pathology / Q000628:therapy*
chemical_list: D002272:Carcinoembryonic Antigen; D053554:Keratin-20; D012333:RNA, Messenger