title: Disseminated and circulating tumor cells in gastrointestinal oncology.
abstract: Circulating (CTCs) and disseminated tumor cells (DTCs) are two different steps in the metastatic process. Several recent techniques have allowed detection of these cells in patients, and have generated many results using different isolation techniques in small cohorts. Herein, we review the detection results and their clinical consequence in esophageal, gastric, pancreatic, colorectal, and liver carcinomas, and discuss their possible applications as new biomarkers.
authors.affiliation: Department of Medical Oncology, Institut Curie, Paris, France. fcbidard@curie.fr
authors.forename: F C
authors.initials: FC
authors.lastname: Bidard
authors.forename: F R
authors.initials: FR
authors.lastname: Ferrand
authors.forename: F
authors.initials: F
authors.lastname: Huguet
authors.forename: P
authors.initials: P
authors.lastname: Hammel
authors.forename: C
authors.initials: C
authors.lastname: Louvet
authors.forename: D
authors.initials: D
authors.lastname: Malka
authors.forename: V
authors.initials: V
authors.lastname: Boige
authors.forename: M
authors.initials: M
authors.lastname: Ducreux
authors.forename: T
authors.initials: T
authors.lastname: Andre
authors.forename: A
authors.initials: A
authors.lastname: de Gramont
authors.forename: P
authors.initials: P
authors.lastname: Mariani
authors.forename: J Y
authors.initials: JY
authors.lastname: Pierga
mesh_terms: D005770:Gastrointestinal Neoplasms / Q000097:blood / Q000473:pathology* / Q000628:therapy; D006801:Humans; D009360:Neoplastic Cells, Circulating