title: Concurrent presentation of aniridia and megalocornea without glaucoma.
abstract: We report an 18-month-old boy who presented with aniridia and megalocornea but no evidence of glaucoma. In children with aniridia, glaucoma often does not present with buphthalmos; because, it typically manifests in preadolescence or adolescence, as progressive changes occur in the drainage angle. Megalocornea, however, in the presence of aniridia strongly suggests glaucoma in early infancy. This case represents a previously unreported association of aniridia and megalocornea in an otherwise-healthy child with good vision.
authors.affiliation: Thomas Eye Group, Atlanta, Georgia, USA.
authors.forename: Stephen N
authors.initials: SN
authors.lastname: Lipsky
authors.forename: Sarwat
authors.initials: S
authors.lastname: Salim
mesh_terms: D015783:Aniridia / Q000235:genetics*; D003315:Cornea / Q000002:abnormalities*; D005124:Eye Abnormalities / Q000235:genetics*; D005901:Glaucoma / Q000235:genetics*; D006068:Gonioscopy; D006801:Humans; D007223:Infant; D007429:Intraocular Pressure / Q000502:physiology; D008297:Male; D014065:Tonometry, Ocular; D014792:Visual Acuity / Q000502:physiology