title: Improved postoperative outcome of segmental fasciectomy in Dupuytren disease by insertion of an absorbable cellulose implant.
abstract: In this case-control prospective study, we investigated if we could improve the surgical outcome of interrupting strands in Dupuytren disease by creating a blocking effect with an absorbable cellulose implant, a known absorbable adhesion barrier. We studied 33 operations in 29 patients who had the potential for recurrent disease. The cellulose was implanted in the first 15 patients. An intraindividual control was added in 4 patients, who were given the implant in 1 of 2 operated hands. Goniometric evolution was monitored on digital photography, and satisfaction was measured on a visual analogue scale (VAS) with a preliminary one year follow-up. With the implant the postoperative range of movement improved significantly (by 33%) and remained unchanged after three months to a one year follow-up. The VAS for satisfaction also improved. We conclude that cellulose implants may improve the outcome of segmental fasciectomy in Dupuytren disease by achieving a better extension of fingers and a higher patients' satisfaction.
authors.affiliation: Orthopaedic Department, Hand Unit, University Hospitals Leuven, Pellenberg Campus, Pellenberg, Belgium. ilse.degreef@uz.kuleuven.ac.be
authors.forename: Ilse
authors.initials: I
authors.lastname: Degreef
authors.forename: Sabine
authors.initials: S
authors.lastname: Tejpar
authors.forename: Luc
authors.initials: L
authors.lastname: De Smet
mesh_terms: D020341:Absorbable Implants; D000368:Aged; D000369:Aged, 80 and over; D016022:Case-Control Studies; D002483:Cellulose, Oxidized / Q000627:therapeutic use*; D004387:Dupuytren Contracture / Q000175:diagnosis / Q000601:surgery*; D000071938:Fasciotomy; D005260:Female; D005500:Follow-Up Studies; D018737:Hand Strength / Q000502:physiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D019637:Orthopedic Procedures / Q000379:methods; D010147:Pain Measurement; D011182:Postoperative Care / Q000379:methods; D011446:Prospective Studies; D016059:Range of Motion, Articular / Q000502:physiology*; D020127:Recovery of Function / Q000502:physiology; D012720:Severity of Illness Index; D018709:Statistics, Nonparametric; D016896:Treatment Outcome
chemical_list: D002483:Cellulose, Oxidized