title: Identification of a higher-order organozincate intermediate involved in Negishi cross-coupling reactions by mass spectrometry and NMR spectroscopy.
abstract: Negishi cross-coupling reactions were analyzed in solution by mass spectrometry and NMR spectroscopy to identify both the effect of LiBr as an additive as well as the purpose of 3-dimethyl-2-imidazolidinone (DMI) as a co-solvent. The results suggest that the main role of DMI is to facilitate a higher order bromozincate formation during the addition of LiBr.
authors.affiliation: Department of Chemistry, York University, 4700 Keele St., Toronto, M3J 1P3, Canada.
authors.forename: Howard N
authors.initials: HN
authors.lastname: Hunter
authors.forename: Niloufar
authors.initials: N
authors.lastname: Hadei
authors.forename: Voislav
authors.initials: V
authors.lastname: Blagojevic
authors.forename: Pascal
authors.initials: P
authors.lastname: Patschinski
authors.forename: George T
authors.initials: GT
authors.lastname: Achonduh
authors.forename: Stephanie
authors.initials: S
authors.lastname: Avola
authors.forename: Diethard K
authors.initials: DK
authors.lastname: Bohme
authors.forename: Michael G
authors.initials: MG
authors.lastname: Organ