title: Evaluation of oral antiseptic rinsing before sputum collection to reduce contamination of mycobacterial cultures.
abstract: To assess whether rinsing with oral antiseptics before sputum collection would reduce contamination of mycobacterial cultures, 120 patients with suspected tuberculosis were randomly assigned to rinse with chlorhexidine or cetylpyridinium mouthwash before collection. The culture contamination rate was significantly lower after rinsing with chlorhexidine before collection, especially for cultures grown in MGIT medium.
authors.affiliation: Núcleo de Doenças Infecciosas, Centro de Ciências da Saúde, Universidade Federal do Espírito Santo, Av. Marechal Campos 1468, Maruípe, Vitória, ES CEP 29040-091, Brazil.
authors.forename: Renata L
authors.initials: RL
authors.lastname: Peres
authors.forename: Moisés
authors.initials: M
authors.lastname: Palaci
authors.forename: Rafaela B
authors.initials: RB
authors.lastname: Loureiro
authors.forename: Reynaldo
authors.initials: R
authors.lastname: Dietze
authors.forename: John L
authors.initials: JL
authors.lastname: Johnson
authors.forename: Jonathan E
authors.initials: JE
authors.lastname: Golub
authors.forename: A
authors.initials: A
authors.lastname: Ruffino-Netto
authors.forename: Ethel L
authors.initials: EL
authors.lastname: Maciel
mesh_terms: D000293:Adolescent; D000328:Adult; D000891:Anti-Infective Agents, Local / Q000008:administration & dosage*; D002594:Cetylpyridinium / Q000008:administration & dosage; D002710:Chlorhexidine / Q000008:administration & dosage; D006801:Humans; D008875:Middle Aged; D009067:Mouthwashes / Q000008:administration & dosage*; D009169:Mycobacterium tuberculosis / Q000302:isolation & purification*; D013183:Sputum / Q000382:microbiology*; D014376:Tuberculosis / Q000175:diagnosis*; D055815:Young Adult
chemical_list: D000891:Anti-Infective Agents, Local; D009067:Mouthwashes; D002594:Cetylpyridinium; D002710:Chlorhexidine