title: Advances in management of the female athlete triad and eating disorders.
abstract: Although there are numerous benefits to women from athletic participation, a complex combination of endocrine and metabolic factors exaggerates risk for a serious health concern: the female athlete triad. The purpose of this article is to provide updates on new issues related to the triad, specifically the relationship between athletic-associated amenorrhea and endothelial dysfunction-a potential fourth component to the triad that is a concern for future cardiovascular risk, public health issues, and athletic performance. Folic acid should be considered a potential safe and inexpensive therapeutic treatment to restore endothelial-dependent vasodilation.
authors.affiliation: Department of Orthopaedic Surgery, Sports Medicine Center, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
authors.forename: Karie N
authors.initials: KN
authors.lastname: Zach
authors.forename: Ariane L
authors.initials: AL
authors.lastname: Smith Machin
authors.forename: Anne Z
authors.initials: AZ
authors.lastname: Hoch
mesh_terms: D000293:Adolescent; D000568:Amenorrhea / Q000628:therapy*; D056352:Athletes; D015519:Bone Density / Q000502:physiology; D015928:Cognitive Behavioral Therapy / Q000639:trends; D004358:Drug Therapy / Q000639:trends; D002149:Energy Intake / Q000502:physiology; D001068:Feeding and Eating Disorders / Q000628:therapy*; D005260:Female; D005492:Folic Acid / Q000008:administration & dosage; D006801:Humans; D008598:Menstruation / Q000502:physiology; D014481:United States
chemical_list: D005492:Folic Acid