title: The surgical and orthodontic management of cherubism in a growing child.
abstract: Cherubism is a rare non-neoplastic disease that affects the jaws causing significant destruction and disfigurement. The disease also affects the normal eruption, occlusion and function of the dento-alveolar complex. Cherubism may radiographically and histologically resemble central giant cell granuloma, fibrous dysplasia and other giant cell lesions. The case of a 15-year 4-month-old girl with no obvious facial swelling or signs of cherubism is described in this report. The patient presented with a dental malocclusion that included the ectopic eruption and displacement of teeth caused by the lesion. The radiographic findings derived from Cone Beam Computed Tomography (CBCT) technology are described. This case report details the orthodontic and surgical diagnosis and management of a teenager during the post growth period.
authors.affiliation: Department of Orthodontics, University of Alabama at Birmingham, School of Dentistry, 1919 7th Avenue South, Birmingham, AL 35294, USA. ckau@uab.edu
authors.forename: Chung How
authors.initials: CH
authors.lastname: Kau
authors.forename: Nada M
authors.initials: NM
authors.lastname: Souccar
authors.forename: Jeryl D
authors.initials: JD
authors.lastname: English
authors.forename: Sherif G
authors.initials: SG
authors.lastname: Kamel
authors.forename: Mark E
authors.initials: ME
authors.lastname: Wong
mesh_terms: D000293:Adolescent; D001706:Biopsy; D002636:Cherubism / Q000601:surgery* / Q000628:therapy; D054893:Cone-Beam Computed Tomography / Q000379:methods; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D021621:Imaging, Three-Dimensional / Q000379:methods; D007372:Interferons / Q000627:therapeutic use; D008312:Malocclusion, Angle Class II / Q000601:surgery* / Q000628:therapy; D008336:Mandibular Diseases / Q000601:surgery* / Q000628:therapy; D008963:Molar / Q000601:surgery; D008964:Molar, Third / Q000601:surgery; D009971:Orthodontics, Corrective / Q000379:methods*; D014079:Tooth Eruption, Ectopic / Q000628:therapy; D014081:Tooth Extraction; D014087:Tooth Movement Techniques / Q000379:methods; D014095:Tooth, Impacted / Q000601:surgery
chemical_list: D007372:Interferons