title: The effect of cetylated fatty esters and physical therapy on myofascial pain syndrome of the neck.
abstract: Participants with Myofascial Pain Syndrome (MPS) of the neck were randomly assigned into 2 groups of the double-blinded study: topical cetylated fatty ester complex (CFEC) cream application plus physical therapy (CF-PT; n=37), and placebo cream application plus physical therapy (PL-PT; n=35). There were 3 visits during 4 weeks of treatment. Physical Therapy (PT), given twice/week, included Ischaemic Compression, Deep Pressure Trigger Point Massage and Myofascial Releases. Topical cream [CFEC cream (5.6%) and 1.5% menthol] or placebo cream [1.5% menthol, in a cream base] was applied twice/day. CF-PT provided the fastest and most effective study treatment modality. The addition of CFEC cream to PT resulted in statistically significant improvements, compared to PL-PT, for reduction of pain, neck disability and life quality indicators. Our results indicate that cetylated derivatives of fatty acids can effectively reduce pain and symptoms associated with neck MPS, when combined with physical therapy.
authors.affiliation: RECOUP Neuromusculoskeletal Rehabilitation Centre, 312, 80 Feet Road, Further Extension of Anjanapura Layout, 10th Block, Bangalore 560062, Karnataka, India. deepak.sharan@recoup.in
authors.forename: Deepak
authors.initials: D
authors.lastname: Sharan
authors.forename: Biju Nirmal
authors.initials: BN
authors.lastname: Jacob
authors.forename: P S
authors.initials: PS
authors.lastname: Ajeesh
authors.forename: Jack B
authors.initials: JB
authors.lastname: Bookout
authors.forename: Raj R
authors.initials: RR
authors.lastname: Barathur
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D004311:Double-Blind Method; D005156:Facial Neuralgia / Q000188:drug therapy* / Q000473:pathology / Q000628:therapy; D005227:Fatty Acids / Q000737:chemistry*; D005260:Female; D006305:Health Status Indicators; D006801:Humans; D008297:Male; D008875:Middle Aged; D019547:Neck Pain / Q000534:rehabilitation*; D010147:Pain Measurement; D026741:Physical Therapy Modalities; D016059:Range of Motion, Articular; D018709:Statistics, Nonparametric; D011795:Surveys and Questionnaires; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D005227:Fatty Acids