title: Adult purpura fulminans associated with non-steroidal anti-inflammatory drug use.
abstract: Purpura fulminans is an acute illness characterized by rapidly progressive dermal vascular thrombosis, leading to hemorrhagic necrosis of the skin. Here, we describe the case of a healthy woman who developed acute disseminated intravascular coagulation (DIC) with purpura fulminans after intramuscular administration of a single dose of ketorolac. Review of literature showed only one case description of non-steroidal anti-inflammatory drug (diclofenac)-related purpura fulminans with DIC.
authors.affiliation: Department of Medicine, SUNY Upstate Medical University, Syracuse, New York, USA. kosarajn@upstate.edu
authors.forename: N
authors.initials: N
authors.lastname: Kosaraju
authors.forename: V
authors.initials: V
authors.lastname: Korrapati
authors.forename: A
authors.initials: A
authors.lastname: Thomas
authors.forename: B R
authors.initials: BR
authors.lastname: James
mesh_terms: D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects*; D004211:Disseminated Intravascular Coagulation / Q000139:chemically induced* / Q000175:diagnosis; D005260:Female; D006801:Humans; D020910:Ketorolac / Q000009:adverse effects*; D008875:Middle Aged; D055665:Purpura Fulminans / Q000139:chemically induced* / Q000175:diagnosis
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D020910:Ketorolac