title: Bilio-intestinal bypass for the treatment of obesity.
abstract: OBJECTIVE
  This study was a retrospective assessment of the results of bilio-intestinal bypass (a variation of the jejuno-ileal bypass, in which the intestinal blind loop is anastomosed to the gallbladder).
  
  
  METHODS
  Seventy-five patients underwent the Eriksson bilio-intestinal bypass since 2003 to January 2009. Mean weight prior to surgery was 115.17 (SD±17.74 kg; range 82-177 kg). Mean preoperative BMI (Body Mass Index) was 41.75 kg/m2 (SD±4.42; range 35-60). Primary criteria taken into consideration have been: weight loss, blood tests, reversal rate and complications.
  
  
  RESULTS
  One year after surgery BMI reported a mean decrease of 28.31% (SD±2.49%) from a mean of 41.75 to a mean 29.72. The mean follow-up is 26.81 months (SD±17.41 months; range 1-72 months). Blood glucose levels at one year follow-up were normalized, shifting from a mean of 138.5 (SD±23.8) to 86.2 (SD±2.6) mg/dL. Diabetic patients were all able to stop hypoglicemic drugs. Serum total cholesterol and triglycerides concentrations decreased of a mean of 31% and 44%. Morbidity was acceptable (two cases of enterorrhage, one biliary leak, one intra-abdominal abscess all treated conservatively). Reversal rate was 2.67%. No mortality was registered.
  
  
  CONCLUSIONS
  Bilio-intestinal bypass is effective in inducing weight loss and metabolic improvement. This procedure is particularly indicated for the heavily obese who do not accept alimentary restrictions but are willing to submit to long-term monitoring.
authors.affiliation: Department of General Surgery, Center for the Treatment of Pathological Obesity, Hospital IGEA, Milan, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Della Barba
authors.forename: G
authors.initials: G
authors.lastname: Lenna
authors.forename: S
authors.initials: S
authors.lastname: Vellini
authors.forename: M
authors.initials: M
authors.lastname: Maino
authors.forename: M
authors.initials: M
authors.lastname: De Simone
authors.forename: F
authors.initials: F
authors.lastname: Piegai
authors.forename: E
authors.initials: E
authors.lastname: Riggio
authors.forename: R A
authors.initials: RA
authors.lastname: Pappalardo
mesh_terms: D000328:Adult; D000368:Aged; D050110:Bariatric Surgery / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000601:surgery*; D012189:Retrospective Studies; D055815:Young Adult