title: Asymmetric organocatalytic synthesis of complex cyclopenta[b]quinoline derivatives.
abstract: An efficient one-pot procedure that provides a direct access to polycyclic hexahydrocyclopenta[b]quinoline derivatives having five stereogenic centers has been developed. The system displays great tolerance toward different aldehydes, anilines, and nitroalkenes. The products are obtained in high yields and excellent enantio- and diastereoselectivities.
authors.affiliation: Center for Catalysis, Aarhus University, 8000 Aarhus C, Denmark.
authors.forename: Kim L
authors.initials: KL
authors.lastname: Jensen
authors.forename: Gustav
authors.initials: G
authors.lastname: Dickmeiss
authors.forename: Bjarke S
authors.initials: BS
authors.lastname: Donslund
authors.forename: Pernille H
authors.initials: PH
authors.lastname: Poulsen
authors.forename: Karl Anker
authors.initials: KA
authors.lastname: Jørgensen
mesh_terms: D000475:Alkenes / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D006571:Heterocyclic Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D009574:Nitro Compounds / Q000737:chemistry*; D011804:Quinolines / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D000475:Alkenes; D006571:Heterocyclic Compounds; D009574:Nitro Compounds; D011804:Quinolines