title: Rapid detection of "highly virulent" Group B Streptococcus ST-17 and emerging ST-1 clones by MALDI-TOF mass spectrometry.
abstract: MALDI-TOF MS identified a 6250-Da protein specific to Sequence Type-1 (ST-1) strains and a 7625-Da protein specific to ST-17 strains when used for identification of Group B streptococci. The strains of these STs are major causes of meningitis and late-onset-disease in neonates. This rapid method of identification could thus be valuable in the evaluation of risk of neonatal diseases.
authors.affiliation: Université François-Rabelais de Tours, UFR de Médecine, EA 3854 Bactéries et Risque Materno-foetal, Institut Fédératif de Recherche 136 Agents Transmissibles et Infectiologie, 37032 Tours Cedex, France. lartigue@med.univ-tours.fr
authors.forename: Marie-Frédérique
authors.initials: MF
authors.lastname: Lartigue
authors.forename: Markus
authors.initials: M
authors.lastname: Kostrzewa
authors.forename: Mazen
authors.initials: M
authors.lastname: Salloum
authors.forename: Eve
authors.initials: E
authors.lastname: Haguenoer
authors.forename: Geneviève
authors.initials: G
authors.lastname: Héry-Arnaud
authors.forename: Anne-Sophie
authors.initials: AS
authors.lastname: Domelier
authors.forename: Simone
authors.initials: S
authors.lastname: Stumpf
authors.forename: Roland
authors.initials: R
authors.lastname: Quentin
mesh_terms: D000328:Adult; D001431:Bacteriological Techniques / Q000379:methods*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / Q000379:methods*; D013290:Streptococcal Infections / Q000175:diagnosis*; D013292:Streptococcus agalactiae / Q000737:chemistry / Q000145:classification* / Q000302:isolation & purification*