title: [Antibiotic therapy in asthma exacerbation and in cystic fibrosis in children].
abstract: Antibiotics have significant role in the treatment of respiratory diseases. The main aim of their use is to treat infection, but anti-inflammatory properties of macrolides are also beneficial in selected diseases. The role of antibiotics in the therapy of asthma exacerbation can be neglected and should be limited to exceptional situations of bacterial infections which are very rare. During last few years the role of atypical infections in asthma inception, induction of exacerbation and modification of chronic course of disease has been discussed. Antibiotics play significant role in cystic fibrosis therapy. They are especially recommended during exacerbation, when new pathogens are revealed and in chronic Pseudomonas aeruginosa infection. This paper includes the principal rules of antibiotics therapy in patients with cystic fibrosis. The role of azithromycin in antiinflammatory therapy in this group of patients is also presented.
authors.affiliation: Klinika Pneumonologii, Alergologii Dzieciecej i Immunologii Klinicznej III Katedry Pediatrii, Uniwersytet Medyczny im. K. Marcinkowskiego w Poznaniu. abreborowicz@wp.pl
authors.forename: Anna
authors.initials: A
authors.lastname: Breborowicz
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001249:Asthma / Q000150:complications* / Q000188:drug therapy*; D017963:Azithromycin / Q000627:therapeutic use; D002648:Child; D003550:Cystic Fibrosis / Q000150:complications*; D006801:Humans; D012141:Respiratory Tract Infections / Q000150:complications / Q000188:drug therapy*
chemical_list: D000900:Anti-Bacterial Agents; D000893:Anti-Inflammatory Agents; D017963:Azithromycin