title: The human brain in a dish: the promise of iPSC-derived neurons.
abstract: Induced pluripotent stem cell-derived neurons from patients promise to fill an important niche between studies in humans and model organisms in deciphering mechanisms and identifying therapeutic avenues for neurologic and psychiatric diseases. Recent work begins to tap this potential and also highlights challenges that must be overcome to be fully realized.
authors.affiliation: Department of Neurobiology, Fairchild Research Building, Room D227, Stanford University, Stanford, CA 94305, USA. ricardo.dolmetsch@stanford.edu
authors.forename: Ricardo
authors.initials: R
authors.lastname: Dolmetsch
authors.forename: Daniel H
authors.initials: DH
authors.lastname: Geschwind
mesh_terms: D000818:Animals; D001921:Brain / Q000166:cytology*; D001927:Brain Diseases / Q000473:pathology; D006801:Humans; D057026:Induced Pluripotent Stem Cells / Q000166:cytology*; D001523:Mental Disorders / Q000473:pathology; D009474:Neurons / Q000166:cytology* / Q000473:pathology