title: Colonic and parastomal ulceration related to nicorandil.
abstract: Nicorandil is an antianginal medication increasingly used in the treatment of severe ischemic heart disease. It has been implicated in the pathogenesis of perianal and perioral ulceration. We report 2 patients with atypical gastrointestinal ulceration due to nicorandil.
authors.affiliation: Department of Surgery, Dumfries and Galloway Royal Infirmary, Dumfries, UK. chrispayne@doctors.org.uk
authors.forename: Christopher J
authors.initials: CJ
authors.lastname: Payne
authors.forename: Stuart C
authors.initials: SC
authors.lastname: Whitelaw
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003108:Colonic Diseases / Q000139:chemically induced* / Q000175:diagnosis; D003113:Colonoscopy; D003125:Colostomy; D003937:Diagnosis, Differential; D004241:Diverticulum, Colon / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D017202:Myocardial Ischemia / Q000188:drug therapy; D020108:Nicorandil / Q000009:adverse effects* / Q000627:therapeutic use; D014456:Ulcer / Q000139:chemically induced* / Q000175:diagnosis; D014665:Vasodilator Agents / Q000009:adverse effects / Q000627:therapeutic use
chemical_list: D014665:Vasodilator Agents; D020108:Nicorandil