title: Primary hepatoid adenocarcinoma of the endometrium with a high alphafetoprotein level.
abstract: Primary hepatoid adenocarcinoma of the endometrium is a rare tumour that is similar to hepatocellular carcinoma histologically. Here, a patient with primary hepatoid carcinoma of the endometrium with a high alphafetoprotein (AFP) level (90,508 ng/mL) is presented in a 75-year-old woman. The pelvic computed tomography and magnetic resonance imaging suggested a submucosal leiomyoma with degeneration or endometrial hyperplasia. However, the endometrial biopsy revealed a primary hepatoid carcinoma of the endometrium. The patient underwent a staging laparotomy including a total abdominal hysterectomy, bilateral salpingo-oophorectomy and lymph node sampling with pelvic cytology. The AFP level can be highly elevated in hepatoid carcinoma of the endometrium.
authors.affiliation: Department of Obstetrics & Gynecology, Korea University College of Medicine, Seoul, Korea. jh36640@gmail.com
authors.forename: Jong Ha
authors.initials: JH
authors.lastname: Hwang
authors.forename: Seung Hun
authors.initials: SH
authors.lastname: Song
authors.forename: Young Hye
authors.initials: YH
authors.lastname: Kim
authors.forename: Bong Kyung
authors.initials: BK
authors.lastname: Shin
authors.forename: Jae Kwan
authors.initials: JK
authors.lastname: Lee
authors.forename: Nak Woo
authors.initials: NW
authors.lastname: Lee
authors.forename: Kyu Wan
authors.initials: KW
authors.lastname: Lee
mesh_terms: D000368:Aged; D018269:Carcinoma, Endometrioid / Q000175:diagnosis / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery; D006528:Carcinoma, Hepatocellular / Q000175:diagnosis / Q000378:metabolism*; D005260:Female; D006801:Humans; D007889:Leiomyoma / Q000175:diagnosis / Q000532:radiotherapy / Q000601:surgery; D008113:Liver Neoplasms / Q000175:diagnosis / Q000378:metabolism*; D009367:Neoplasm Staging; D016896:Treatment Outcome; D014594:Uterine Neoplasms / Q000175:diagnosis / Q000532:radiotherapy / Q000601:surgery; D000509:alpha-Fetoproteins / Q000032:analysis / Q000096:biosynthesis*
chemical_list: D000509:alpha-Fetoproteins