title: [Uncommon cutaneous ulcerative and systemic sarcoidosis. Successful treatment with hydroxychloroquine and compression therapy].
abstract: Sarcoidosis is a granulomatous multisystemic disease of unclear etiology, which can affect any organ. The cutaneous manifestations are variable, but ulcerative cutaneous sarcoidosis is very rare. One must rule out other granulomatous skin diseases, especially necrobiosis lipoidica. There is no standarized therapy; usually an interdisciplinary approach over years taking multiple side effects into consideration is needed. A 58-year-old woman with a long history of cutaneous, nodal and pulmonary sarcoidosis suddenly developed ulcerations within the disseminated skin lesions on her legs. The combination of systemic hydroxychloroquine and modern wound management lead to complete healing of the ulcers and a significant improvement in the remaining skin lesions.
authors.affiliation: Abteilung Dermatologie, Venerologie und Allergologie, Georg-August-Universität Göttingen, Universitäts-Hautklinik Göttingen, Göttingen, Deutschland. d_meyersburg@med.uni-goettingen.de
authors.forename: D
authors.initials: D
authors.lastname: Meyersburg
authors.forename: M P
authors.initials: MP
authors.lastname: Schön
authors.forename: H P
authors.initials: HP
authors.lastname: Bertsch
authors.forename: C S
authors.initials: CS
authors.lastname: Seitz
mesh_terms: D018501:Antirheumatic Agents / Q000627:therapeutic use*; D001706:Biopsy; D003131:Combined Modality Therapy; D003646:Debridement; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D006886:Hydroxychloroquine / Q000627:therapeutic use*; D007871:Leg Ulcer / Q000175:diagnosis / Q000473:pathology / Q000628:therapy*; D008875:Middle Aged; D012507:Sarcoidosis / Q000175:diagnosis / Q000473:pathology / Q000628:therapy*; D012867:Skin / Q000473:pathology; D012871:Skin Diseases / Q000175:diagnosis / Q000473:pathology / Q000628:therapy*; D053828:Stockings, Compression
chemical_list: D018501:Antirheumatic Agents; D006886:Hydroxychloroquine