title: [Anticholinergic agents for overactive bladder syndrome: current head-to-head comparison].
abstract: Overactive-bladder syndrome is characterized by the symptoms pollakisuria, nocturia and urgency with and without urge incontinence. The primary diagnostic procedure includes noninvasive or minimally invasive techniques. Antimuscarinic drugs lead within the therapeutic cascade. Only after unsuccessful use of several antimuscarinics should further treatment options such as electromotive drug administration or infiltration of the detrusor muscle with botulinum toxin A be discussed. The presented review article tries to give an overview by including the existing head-to-head-studies in this field.
authors.affiliation: Klinik für Urologie und Kinderurologie, Klinikum Niederberg, Robert-Koch-Straße 2, 42549 Velbert, Deutschland. goepel@klinikum-niederberg.de
authors.forename: M
authors.initials: M
authors.lastname: Goepel
authors.forename: D
authors.initials: D
authors.lastname: Schultz-Lampel
mesh_terms: D000368:Aged; D019274:Botulinum Toxins, Type A / Q000627:therapeutic use; D018680:Cholinergic Antagonists / Q000009:adverse effects / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008875:Middle Aged; D018727:Muscarinic Antagonists / Q000009:adverse effects / Q000627:therapeutic use; D053158:Nocturia / Q000175:diagnosis / Q000188:drug therapy*; D016032:Randomized Controlled Trials as Topic; D053201:Urinary Bladder, Overactive / Q000175:diagnosis / Q000188:drug therapy*; D053202:Urinary Incontinence, Urge / Q000188:drug therapy*; D014563:Urodynamics / Q000187:drug effects
chemical_list: D018680:Cholinergic Antagonists; D018727:Muscarinic Antagonists; D019274:Botulinum Toxins, Type A