title: Performance of the CRAFTi portable fluorometer comparing with the HPLC method for determining serum retinol.
abstract: OBJECTIVE
  To determine the performance of a portable fluorometer for measuring serum retinol (SR) concentration.
  
  
  METHODS
  Serum samples were obtained from 75 factory worker women and 143 school children. SR concentration was quantified using a portable fluorometer ('CRAFTi') and HPLC analysis.
  
  
  RESULTS
  SR by HPLC (1.23 ± 0.43 μmol/L) and CRAFTi (1.16 ± 0.46 μmol/L) was significantly correlated. Sensitivity and specificity were 85.3% and 78.0% (cutoff of 1.05 μmol/L). Kappa statistics showed moderate agreement.
  
  
  CONCLUSIONS
  CRAFTi portable fluorometer is a promising field-friendly tool for screening vitamin A deficiency.
authors.affiliation: Institute of Nutrition, Mahidol University, Nakhon Pathom 73170, Thailand.
authors.forename: Laksana
authors.initials: L
authors.lastname: Chaimongkol
authors.forename: Siwaporn
authors.initials: S
authors.lastname: Pinkaew
authors.forename: Harold C
authors.initials: HC
authors.lastname: Furr
authors.forename: John
authors.initials: J
authors.lastname: Estes
authors.forename: Neal E
authors.initials: NE
authors.lastname: Craft
authors.forename: Emorn
authors.initials: E
authors.lastname: Wasantwisut
authors.forename: Pattanee
authors.initials: P
authors.lastname: Winichagoon
mesh_terms: D000328:Adult; D002648:Child; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D005260:Female; D005470:Fluorometry / Q000295:instrumentation*; D006801:Humans; D012680:Sensitivity and Specificity; D014801:Vitamin A / Q000097:blood*; D014802:Vitamin A Deficiency / Q000175:diagnosis
chemical_list: D014801:Vitamin A