title: Encoded peptide libraries and the discovery of new cell binding ligands.
abstract: Cells over-expressing integrins or CCR6 were incubated on a DNA microarray, pre-hybridized with a 10,000 member PNA-encoded peptide library allowing novel cell specific ligands for integrins and CCR6 to be identified.
authors.affiliation: School of Chemistry, EastChem, The University of Edinburgh, Joseph Black Building, West Mains Road, Edinburgh, EH9 3JJ, UK.
authors.forename: Nina
authors.initials: N
authors.lastname: Svensen
authors.forename: Juan José
authors.initials: JJ
authors.lastname: Díaz-Mochón
authors.forename: Mark
authors.initials: M
authors.lastname: Bradley
mesh_terms: D002460:Cell Line; D006801:Humans; D016023:Integrins / Q000378:metabolism*; D008024:Ligands; D046228:Microarray Analysis / Q000379:methods*; D019151:Peptide Library; D011485:Protein Binding; D054399:Receptors, CCR6 / Q000378:metabolism*
chemical_list: D016023:Integrins; D008024:Ligands; D019151:Peptide Library; D054399:Receptors, CCR6