title: Sentinel lymph node biopsy in breast cancer patients with previous breast augmentation surgery.
abstract: The number of breast augmentation surgeries (BAS) has increased. Therefore, the number of breast cancer patients with history of BAS has also increased. In this paper, we present two cases of sentinel lymph node biopsy (SLNB) in patients with previous BAS who were diagnosed with breast cancer. The patients were augmented using different approach; the first case was augmented through transaxillary incision, whereas the second case was augmented through periareolar incision. Lymphoscintigraphy (LPG) was performed on the patients 1 day prior to operation, enabling confirmation of lymphatic flow and SLN in both patients. SLNB was successfully performed in both cases. In one patient, SLNB was performed using indocyanine green (ICG) fluorescence and the Photodynamic Eye (PDE) system. Regardless of history of BAS, ICG and PDE system showed lymphatic flow and SLN in real time. LPG and ICG fluorescence were useful methods for SLN detection in patients with previous BAS, being able to confirm lymph flow before operation. Biopsy methods using LPG and PDE system were considered useful for difficult confirmation of lymph flow after breast augmentation. This is the first report of SLNB using ICG and PDE system for patients with previous BAS.
authors.affiliation: Department of Breast Oncology, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.
authors.forename: Tomoya
authors.initials: T
authors.lastname: Nagao
authors.forename: Takashi
authors.initials: T
authors.lastname: Hojo
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Kurihara
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Tsuda
authors.forename: Sadako
authors.initials: S
authors.lastname: Tanaka-Akashi
authors.forename: Takayuki
authors.initials: T
authors.lastname: Kinoshita
mesh_terms: D000328:Adult; D001943:Breast Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery*; D005260:Female; D006801:Humans; D007208:Indocyanine Green; D061305:Lymphoscintigraphy; D016462:Mammaplasty; D015412:Mastectomy, Segmental / Q000379:methods; D008875:Middle Aged; D021701:Sentinel Lymph Node Biopsy / Q000379:methods*
chemical_list: D007208:Indocyanine Green