title: Ketogenic diet does not change NKCC1 and KCC2 expression in rat hippocampus.
abstract: In control rats, we examined the effects of ketogenic diet on NKCC1 and KCC2 expression levels in hippocampus. Neither the number of NKCC1 immunoreactive cells nor the intensity of labeling of KCC2 was found to modify in hippocampus of the rats after ketogenic diet treatment. These results indicate that ketogenic diet by itself does not modify the expression of these cation chloride cotransporters.
authors.affiliation: Laboratorio de Neuromorfometría, Instituto Nacional de Pediatría, Insurgentes Sur 3700-C, Col. Insurgentes Cuicuilco, Del. Coyoacán, México D.F. 04530, México. ggomez@fisio.cinvestav.mx
authors.forename: Gisela
authors.initials: G
authors.lastname: Gómez-Lira
authors.forename: Julieta Griselda
authors.initials: JG
authors.lastname: Mendoza-Torreblanca
authors.forename: Leticia
authors.initials: L
authors.lastname: Granados-Rojas
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D055423:Diet, Ketogenic / Q000379:methods*; D005786:Gene Expression Regulation / Q000187:drug effects*; D006624:Hippocampus / Q000033:anatomy & histology / Q000187:drug effects*; D008297:Male; D009474:Neurons / Q000378:metabolism; D051381:Rats; D017207:Rats, Sprague-Dawley; D028021:Sodium-Potassium-Chloride Symporters / Q000378:metabolism*; D064506:Solute Carrier Family 12, Member 2; D018709:Statistics, Nonparametric; D027981:Symporters / Q000378:metabolism*; D000096922:K Cl- Cotransporters
chemical_list: D028021:Sodium-Potassium-Chloride Symporters; D064506:Solute Carrier Family 12, Member 2; D027981:Symporters; D000096922:K Cl- Cotransporters; C578879:Slc12a2 protein, rat