title: [Comparison of Lasik with femtosecond laser versus Lasik with mechanical microkeratome: predictability of flap depth, corneal biomechanical effects and optical aberrations].
abstract: OBJECTIVE
  To compare the predictability of flap thickness, high-order optic aberrations (HOAs), and biomechanical properties of cornea between patients treated by Lasik with mechanical microkeratome versus patients treated by FemtoLasik.
  
  
  METHODS
  Department of ophthalmology, Pellegrin University Hospital, Bordeaux, France.
  
  
  METHODS
  We conducted a retrospective study on 53 myopic patients who underwent Lasik with either mechanical microkeratome (MK group) or femtosecond laser (FS group). Refraction, central corneal thickness, high-order optic aberrations (HOAs), corneal hysteresis (CH), and corneal resistance factor (CRF), were analysed pre- and postoperatively in both groups. The central corneal thickness was measured with OCT-Visante(®) (Carl-Zeiss, Meditec), biomechanical parameters with ORA(®) (Reichert), and optical aberrations with the Wave Scan(®) (AMO) aberrometer.
  
  
  RESULTS
  We included 44 eyes of 22 patients in the MK group and 62 eyes of 31 patients in the FS group. Preoperatively, the mean best-corrected visual acuity was 0.95 in both groups. In the MK group, the flap was significantly thicker than expected (162/130 μm), but in the FS group, there was no significant difference (117/120 μm). The biomechanical properties of the cornea were lower in both groups independently of the flap cutting technique. The HOAs increased after Lasik and were not influenced by the flap cutting technique.
  
  
  CONCLUSIONS
  Neither mechanical microkeratome, nor femtosecond laser for flap creation, increases HOAs and the biomechanical changes of the cornea, according to ORA(®), significantly after Lasik.
authors.affiliation: Service d'Ophtalmologie, CHU Pellegrin, place Amélie-Rabat-Léon, 33000 Bordeaux, France. xavkouassi@yahoo.fr
authors.forename: F-X
authors.initials: FX
authors.lastname: Kouassi
authors.forename: M
authors.initials: M
authors.lastname: Blaizeau
authors.forename: C
authors.initials: C
authors.lastname: Buestel
authors.forename: C
authors.initials: C
authors.lastname: Schweitzer
authors.forename: A
authors.initials: A
authors.lastname: Gallois
authors.forename: J
authors.initials: J
authors.lastname: Colin
authors.forename: D
authors.initials: D
authors.lastname: Touboul
mesh_terms: D000328:Adult; D001696:Biomechanical Phenomena; D003315:Cornea / Q000473:pathology*; D065306:Corneal Injuries; D005128:Eye Diseases / Q000453:epidemiology / Q000209:etiology*; D058752:Free Tissue Flaps / Q000473:pathology*; D006801:Humans; D020731:Keratomileusis, Laser In Situ / Q000009:adverse effects* / Q000295:instrumentation* / Q000379:methods*; D007834:Lasers; D055595:Mechanical Phenomena; D008866:Microsurgery / Q000295:instrumentation / Q000379:methods; D013508:Ophthalmologic Surgical Procedures / Q000009:adverse effects / Q000379:methods; D009929:Organ Size; D011183:Postoperative Complications / Q000453:epidemiology / Q000209:etiology; D015203:Reproducibility of Results; D012189:Retrospective Studies