title: Cost-effectiveness and cost-benefit of a lifestyle intervention for workers in the construction industry at risk for cardiovascular disease.
abstract: OBJECTIVE
  To investigate the cost-effectiveness and cost-benefit of a lifestyle intervention for construction workers with an elevated risk of cardiovascular disease.
  
  
  METHODS
  In this randomized controlled trial, usual care was compared to a 6-month individual-based lifestyle intervention. At 6 and 12 months, weight, absenteeism, health care use, and lifestyle-related expenses were determined. Missing data were imputed. A cost-effectiveness analysis was performed from a societal perspective. Uncertainty around the incremental cost-effectiveness ratio (ICER) was estimated by bootstrapped cost-effect pairs. A cost-benefit analysis was performed from an employer's perspective, subtracting the incremental costs from the incremental benefits.
  
  
  RESULTS
  The ICER was € 145/kg weight loss. The difference between intervention and control group in net employer costs was € 254 (95% CI: -1070 to 1536).
  
  
  CONCLUSIONS
  Implementation of this important and effective intervention depends on the societal and employer's willingness to pay.
authors.affiliation: Department of Public and Occupational Health, EMGO Institute for Health and Care Research, VU University Medical Center, Van der Boechorststraat 7, Amsterdam, the Netherlands.
authors.forename: Iris F
authors.initials: IF
authors.lastname: Groeneveld
authors.forename: Marieke F
authors.initials: MF
authors.lastname: van Wier
authors.forename: Karin I
authors.initials: KI
authors.lastname: Proper
authors.forename: Judith E
authors.initials: JE
authors.lastname: Bosmans
authors.forename: Willem
authors.initials: W
authors.lastname: van Mechelen
authors.forename: Allard J
authors.initials: AJ
authors.lastname: van der Beek
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002318:Cardiovascular Diseases / Q000517:prevention & control*; D003362:Cost-Benefit Analysis; D003376:Counseling / Q000191:economics* / Q000379:methods; D005160:Facility Design and Construction; D015438:Health Behavior; D006293:Health Promotion / Q000191:economics* / Q000379:methods*; D006801:Humans; D008019:Life Style; D016014:Linear Models; D008297:Male; D008875:Middle Aged; D009786:Occupational Health Services / Q000191:economics*; D012307:Risk Factors; D015431:Weight Loss; D055815:Young Adult