title: G-quartet, G-quadruplex, and G-wire regulated by chemical stimuli.
abstract: Guanine-rich DNA, which is widely distributed in the human genome, can fold into a supramolecular structure called the G-wire. The G-wire possesses promising characteristics as a functional element for various applications in vitro and in vivo. Here, we describe the preparative procedures for the G-wire and signatures of G-wire formation. Procedures for the regulation of G-wire formation by chemical stimuli will be useful for in vivo and in vitro applications.
authors.affiliation: Faculty of Frontiers of Innovative Research in Science and Technology (FIRST), and Frontier Institute for Biomolecular Engineering Research (FIBER), Konan University, Kobe, Japan.
authors.forename: Daisuke
authors.initials: D
authors.lastname: Miyoshi
authors.forename: Naoki
authors.initials: N
authors.lastname: Sugimoto
mesh_terms: D001482:Base Composition; D004247:DNA / Q000737:chemistry* / Q000648:ultrastructure; D054856:G-Quadruplexes; D006147:Guanine / Q000737:chemistry; D049329:Nanostructures / Q000737:chemistry*; D036103:Nanotechnology / Q000379:methods*; D009690:Nucleic Acid Conformation
chemical_list: D006147:Guanine; D004247:DNA