title: Macrophages as a battleground for toxoplasma pathogenesis.
abstract: In this issue of Cell Host & Microbe, Jensen et al. (2011) show that clonal lineages of Toxoplasma gondii have evolved distinct ways of subverting their favored host cell, the macrophage. The results suggest that T. gondii and the ROP kinases can be used to probe immune signaling pathways.
authors.affiliation: Departments of Infectious Diseases and Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA. peter.murray@stjude.org
authors.forename: Peter J
authors.initials: PJ
authors.lastname: Murray
mesh_terms: D000818:Animals; D006801:Humans; D008264:Macrophages / Q000276:immunology / Q000469:parasitology*; D051379:Mice; D015800:Protozoan Proteins / Q000235:genetics / Q000276:immunology; D014122:Toxoplasma / Q000145:classification / Q000235:genetics / Q000276:immunology / Q000472:pathogenicity*; D014123:Toxoplasmosis / Q000276:immunology / Q000469:parasitology*
chemical_list: D015800:Protozoan Proteins