title: Validation of a new non-invasive blood pressure measurement method on mice via pulse wave propagation time measurement on a cuff.
abstract: In the present article, we describe the validation of a new non-invasive method for measuring blood pressure (BP) which also enables to determine the three BP values: systolic, diastolic and mean value. Our method is based on the pulse transit time (PTT) measurement along an artery directly at the BP cuff. The accuracy of this method was evaluated by comparison with the direct simultaneous measurement of blood pressure from 40 anesthetized female mice. Close correlation between the gained data from these two methods was observed.
authors.affiliation: Mannheim Biomedical Engineering Laboratories (MABEL), University Hospital Mannheim, Heidelberg University, Germany. p.nguyen@hs-mannheim.de
authors.forename: Xuan P
authors.initials: XP
authors.lastname: Nguyen
authors.forename: Ralf
authors.initials: R
authors.lastname: Kronemayer
authors.forename: Peter
authors.initials: P
authors.lastname: Herrmann
authors.forename: Atila
authors.initials: A
authors.lastname: Mejía
authors.forename: Zamira
authors.initials: Z
authors.lastname: Daw
authors.forename: Xuan D
authors.initials: XD
authors.lastname: Nguyen
authors.forename: Bettina
authors.initials: B
authors.lastname: Kränzlin
authors.forename: Norbert
authors.initials: N
authors.lastname: Gretz
mesh_terms: D000465:Algorithms; D000818:Animals; D001794:Blood Pressure / Q000502:physiology*; D001795:Blood Pressure Determination / Q000295:instrumentation* / Q000662:veterinary*; D003936:Diagnosis, Computer-Assisted / Q000295:instrumentation / Q000379:methods* / Q000662:veterinary*; D004867:Equipment Design; D019544:Equipment Failure Analysis; D005260:Female; D006339:Heart Rate / Q000502:physiology*; D051379:Mice; D011673:Pulsatile Flow / Q000502:physiology*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity