title: A lipid kinase cousin cooperates to promote cancer.
abstract: Phosphoinositide 3-kinases (PI3Ks) are considered promising drug targets in oncology. In this issue of Cancer Cell, Schmid et al. demonstrate that the PI3Kγ isoform is required for inflammatory myeloid cells to traffic to tumors. Though tumor cells do not express PI3Kγ, selective inhibition of this isoform suppresses tumor growth and angiogenesis.
authors.affiliation: Department of Molecular Biology and Biochemistry, University of California, Irvine, USA.
authors.forename: Brandon
authors.initials: B
authors.lastname: Beagle
authors.forename: David A
authors.initials: DA
authors.lastname: Fruman