title: Is the diagnosis of atypical glandular cells of undetermined significance associated with greater risk at an inner city hospital?
abstract: OBJECTIVE
  To test the hypothesis that the high-risk patients at an inner city hospital with atypical glandular cells of undetermined significance (AGC) on their Pap smears have a higher rate of underlying significant pathology than that reported in published data.
  
  
  METHODS
  This was an Institutional Review Board-approved retrospective review of all AGC Pap smears performed at University Hospital, Newark, New Jersey, between January 1, 2001, and July 30, 2008. We defined significant pathology as cervical intraepithelial neoplasia 2 (CIN 2) or greater, endocervical adenocarcinoma in situ or greater, or simple hyperplasia or greater of the endometrium.
  
  
  RESULTS
  Medical records of 126 patients were reviewed. Forty did not meet inclusion criteria; 86 patients were included in the analysis. Thirty of the 86 (34.9%) patients were found to have significant pathology.
  
  
  CONCLUSIONS
  Patients with AGC Pap results at our inner city hospital have a high risk for underlying significant pathology.
authors.affiliation: Department of Pathology and Laboratory Medicine, University of Medicine and Dentistry of New Jersey-New Jersey Medical School, Newark, New Jersey 07103, USA. hellerds@umdnj.edu
authors.forename: Debra S
authors.initials: DS
authors.lastname: Heller
authors.forename: Kara
authors.initials: K
authors.lastname: Goldman
authors.forename: Laura T
authors.initials: LT
authors.lastname: Goldsmith
authors.forename: Bernadette
authors.initials: B
authors.lastname: Cracchiolo
mesh_terms: D002277:Carcinoma / Q000175:diagnosis; D002584:Cervix Uteri / Q000473:pathology*; D005260:Female; D006786:Hospitals, Urban; D006801:Humans; D006965:Hyperplasia / Q000175:diagnosis; D065006:Papanicolaou Test; D012189:Retrospective Studies; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis*; D014626:Vaginal Smears; D002578:Uterine Cervical Dysplasia / Q000175:diagnosis