title: Monovalent, clickable, uncharged, water-soluble perylenediimide-cored dendrimers for target-specific fluorescent biolabeling.
abstract: Herein we report the synthesis of water-soluble polyglycerol-dendronized perylenediimides with a single reactive group that undergoes high-yielding click reactions. Single-molecule studies and target-specific biolabeling are reported, including the highly specific labeling of proteins on the surface of living bacterial and mammalian cells.
authors.affiliation: Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA.
authors.forename: Si Kyung
authors.initials: SK
authors.lastname: Yang
authors.forename: Xinghua
authors.initials: X
authors.lastname: Shi
authors.forename: Seongjin
authors.initials: S
authors.lastname: Park
authors.forename: Sultan
authors.initials: S
authors.lastname: Doganay
authors.forename: Taekjip
authors.initials: T
authors.lastname: Ha
authors.forename: Steven C
authors.initials: SC
authors.lastname: Zimmerman
mesh_terms: D001426:Bacterial Proteins / Q000378:metabolism; D057930:Click Chemistry; D050091:Dendrimers / Q000138:chemical synthesis / Q000737:chemistry* / Q000378:metabolism; D004926:Escherichia coli / Q000166:cytology; D005456:Fluorescent Dyes / Q000138:chemical synthesis / Q000737:chemistry* / Q000378:metabolism; D005990:Glycerol / Q000737:chemistry; D006367:HeLa Cells; D006801:Humans; D007094:Imides / Q000737:chemistry*; D057054:Molecular Imaging; D010569:Perylene / Q000031:analogs & derivatives* / Q000737:chemistry; D011108:Polymers / Q000737:chemistry; D012995:Solubility; D013194:Staining and Labeling; D013379:Substrate Specificity; D014867:Water / Q000737:chemistry*
chemical_list: D001426:Bacterial Proteins; D050091:Dendrimers; D005456:Fluorescent Dyes; D007094:Imides; D011108:Polymers; C521332:perylenediimide; D014867:Water; C043941:polyglycerol; D010569:Perylene; D005990:Glycerol