title: Bulky, optically active P-stereogenic phosphine-boranes from pure H-menthylphosphinates.
abstract: The transformation of readily available pure-H-menthylphosphinates into chiral phosphinous acid-boranes permits the elaboration of bulky P-stereogenic secondary phosphine-boranes. Taking advantage of the synthetic potential of these compounds, a broad range of hindered P-chiral tertiary phosphine-boranes has been prepared with excellent enantiomeric excesses. The utility of bulky o-tolylphosphines was illustrated by the synthesis of a rare enantiopure phosphapalladacycle (S(P),S(P))-12.
authors.affiliation: Equipe Chirosciences, UMR CNRS 6263-ISM2 Université Aix-Marseille III, Ecole Centrale de Marseille Av. Escadrille Normandie Niemen, 13397 Marseille Cedex 20, France.
authors.forename: David
authors.initials: D
authors.lastname: Gatineau
authors.forename: Laurent
authors.initials: L
authors.lastname: Giordano
authors.forename: Gérard
authors.initials: G
authors.lastname: Buono