title: [Dosimetry comparison of irradiation with conformal radiotherapy, intensity modulated radiotherapy, conformal radiotherapy in stereotactic conditions and robotic stereotactic radiotherapy for benign brain tumours].
abstract: OBJECTIVE
  To compare several techniques in order to determine the best treatment for benign brain tumours.
  
  
  METHODS
  A retrospective study was performed for five patients who received 3D-conformal radiotherapy, intensity modulated radiotherapy or CyberKnife(®). These patients had a meningioma, a pituitary tumour, a craniopharyngioma or a neurinoma. In each case, these treatment plans were optimised and compared with the three other dosimetries. Radiobiological or positioning parameters were evaluated, as well as dosimetric parameters, in order to compare treatments with different characteristics.
  
  
  RESULTS
  The dosimetric parameters showed that the choice of treatment seemed to be determined mostly by tumour size, shape and proximity with organs at risk (not tumour localisation). Whereas the results showed no significant deviations with regards to the radiobiological parameters. Therefore, with these parameters, it was difficult to give priority to a treatment.
  
  
  CONCLUSIONS
  With regards to benign brain tumours of medium or large size, intensity modulated radiotherapy seemed the recommended treatment. It enabled to obtain a good ratio between efficacy and toxicity for tumours that are really close to organs at risk. Concerning small benign brain tumours, the CyberKnife(®) was probably the best treatment.
authors.affiliation: Département de radiophysique, centre Alexis-Vautrin, avenue de Bourgogne, 54511 Vandœuvre-lès-Nancy cedex, France. e.spasic@nancy.fnclcc.fr
authors.forename: E
authors.initials: E
authors.lastname: Spasic
authors.forename: I
authors.initials: I
authors.lastname: Buchheit
authors.forename: V
authors.initials: V
authors.lastname: Bernier
authors.forename: A
authors.initials: A
authors.lastname: Noël
mesh_terms: D001932:Brain Neoplasms / Q000532:radiotherapy*; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted; D020266:Radiotherapy, Conformal / Q000379:methods*; D050397:Radiotherapy, Intensity-Modulated / Q000379:methods*; D012189:Retrospective Studies; D012371:Robotics; D013238:Stereotaxic Techniques