title: Exsanguination by intent: controlled phlebotomy during resection of a giant vascular malformation in a 22-month-old child.
abstract: Resection of large vascular malformations may require transection across the lesion, resulting in uncontrollable bleeding with the risk of exsanguination or massive transfusion-related complications such as hyperkalemic cardiac arrest. We present the anesthetic management of a 22-month-old child with a giant vascular malformation who required surgical intervention because of increasing pain and bleeding from the lesion. As a standard resection carried a high risk of mortality for the patient, a novel surgical approach was performed, consisting of gradual compression of the lesion, reducing its base to allow transection across the smallest possible area. This compression resulted in acute massive autotransfusion managed by therapeutic phlebotomy of more than twice the circulating blood volume of the patient, guided by CVP and blood pressure. Although subsequent resection was still associated with large blood loss, the hemodynamic course of the patient was stable, and both bleeding and massive transfusion occurred in a controlled fashion allowing safe and successful resection of the malformation.
authors.affiliation: Department of Anesthesiology, Perioperative and Pain Medicine, Children's Hospital Boston, Boston, MA 02115, USA. ellen.choi@childrens.harvard.edu
authors.forename: Ellen
authors.initials: E
authors.lastname: Choi
authors.forename: Mary
authors.initials: M
authors.lastname: Landrigan-Ossar
authors.forename: Steven J
authors.initials: SJ
authors.lastname: Fishman
authors.forename: Christian
authors.initials: C
authors.lastname: Seefelder
mesh_terms: D000768:Anesthesia, General; D001165:Arteriovenous Malformations / Q000473:pathology / Q000601:surgery*; D016063:Blood Loss, Surgical; D001794:Blood Pressure / Q000502:physiology; D001803:Blood Transfusion; D001804:Blood Transfusion, Autologous; D002496:Central Venous Pressure / Q000502:physiology; D058734:Exsanguination; D006801:Humans; D007223:Infant; D008297:Male; D010146:Pain / Q000209:etiology; D018962:Phlebotomy / Q000379:methods*; D011296:Prenatal Diagnosis; D011300:Preoperative Care; D016684:Prone Position