title: Nasopharyngeal dendritic cell sarcoma, not otherwise specified, in a 34-year-old man.
abstract: Dendritic cell sarcoma, not otherwise specified (NOS), is an entity that is poorly defined because of its rarity and poorly understood pathogenesis. It is characterized by positive immunohistochemical staining for S-100 and CD1a, along with an absence of cytoplasmic Birbeck granules on electron microscopy. We report the case of a surgically inaccessible nasopharyngeal dendritic cell sarcoma, NOS, in a 34-year-old man. Treatment with chemotherapy along with adjuvant radiation therapy was successful in decreasing the size of the nasopharyngeal mass, and the patient remained free of any evidence of recurrence nearly 5 years after treatment.
authors.affiliation: Department of Radiology, University of Mississippi Medical Center, Jackson, MS, USA. bhorton1984@hotmail.com
authors.forename: William B
authors.initials: WB
authors.lastname: Horton
authors.forename: David A
authors.initials: DA
authors.lastname: Joyner
authors.forename: William P
authors.initials: WP
authors.lastname: Daley
authors.forename: Karen T
authors.initials: KT
authors.lastname: Pitman
authors.forename: Majid A
authors.initials: MA
authors.lastname: Khan
mesh_terms: D000328:Adult; D000970:Antineoplastic Agents / Q000008:administration & dosage*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D014408:Biomarkers, Tumor; D054739:Dendritic Cell Sarcoma, Interdigitating / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology*; D006801:Humans; D007124:Immunoenzyme Techniques; D008297:Male; D009303:Nasopharyngeal Neoplasms / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology*; D009418:S100 Proteins
chemical_list: D000970:Antineoplastic Agents; D014408:Biomarkers, Tumor; D009418:S100 Proteins