title: A novel 8.O.6'-neolignan from Taxillus theifer.
abstract: A new 8.O.6'-neolignan, threo-(7R, 8R)-7-acetoxy-3',4'-dimethoxy-3,4-dimethoxy-Δ-(8')-8.O.6'-neolignan (1) along with two known lignans (2) and (3), was isolated from the leaves and stems of Taxillus theifer. Structural elucidation was carried out by 1-D and 2-D-NMR spectroscopic methods, and the absolute configurations of C-7 and C-8 in 1 were determined on the basis of circular dichroism. Compound 2 is threo-7-acetoxy-3'-methoxy-3,4-dimethoxy-Δ-(7')-8.O.4'-neolignan obtained from a natural source for the first time, previously derived from a synthesis study of 8,4'-oxyneolignans.
authors.affiliation: National Research Institute of Chinese Medicine , Taipei 112 , Taiwan. lclin@nricm.edu.tw
authors.forename: Lie-Chwen
authors.initials: LC
authors.lastname: Lin
authors.forename: Tung-Hu
authors.initials: TH
authors.lastname: Tsai
authors.forename: Shao-Chieh
authors.initials: SC
authors.lastname: Su
mesh_terms: D002942:Circular Dichroism; D017705:Lignans / Q000737:chemistry* / Q000302:isolation & purification; D028183:Loranthaceae / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D018515:Plant Leaves / Q000737:chemistry*; D018547:Plant Stems / Q000737:chemistry
chemical_list: D017705:Lignans