title: [Cannabis hyperemesis syndrome].
abstract: We present the course of cyclical hyperemesis most likely induced by cannabis in a young cannabis-dependent, but otherwise healthy female adult. Cyclical hyperemesis developed in parallel to increasing cannabis inhalation, and remitted completely within a few days of abstinence in a protective inpatient setting. Just as in those increasing cases which can be found in literature, the hyperemesis improved by taking a hot shower or bath at the beginning of the detoxification. This thermosensitivity, along with the detection of a central disturbance of the thyroid axis, points to the hypothalamic cannabinoid system being involved in cannabis-induced cyclical hyperemesis. The patient was followed up for 4 months without any re-occurrence of the syndrome during controlled cannabis abstinence.
authors.affiliation: Klinik für Psychiatrie und Psychotherapie, LVR-Klinikum Essen, Universität Duisburg/Essen. udo.bonnet@uni-due.de
authors.forename: U
authors.initials: U
authors.lastname: Bonnet
authors.forename: D-I
authors.initials: DI
authors.lastname: Chang
authors.forename: N
authors.initials: N
authors.lastname: Scherbaum
mesh_terms: D000328:Adult; D000932:Antiemetics / Q000627:therapeutic use; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007031:Hypothalamus / Q000503:physiopathology; D002189:Marijuana Abuse / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology; D011569:Psychiatric Status Rating Scales; D013961:Thyroid Gland / Q000503:physiopathology; D014839:Vomiting / Q000139:chemically induced* / Q000175:diagnosis / Q000503:physiopathology
chemical_list: D000932:Antiemetics