title: Measurement of the reduced scattering coefficient of turbid media using single fiber reflectance spectroscopy: fiber diameter and phase function dependence.
abstract: This paper presents a relationship between the intensity collected by a single fiber reflectance device (R(SF)) and the fiber diameter (d(fib)) and the reduced scattering coefficient ( μs') and phase function (p(θ)) of a turbid medium. Monte Carlo simulations are used to identify and model a relationship between R(SF) and dimensionless scattering ( μs'dfib). For μs'dfib > 10 we find that R(SF) is insensitive to p(θ). A solid optical phantom is constructed with μs' ≈ 220 mm-1 and is used to convert R(SF) of any turbid medium to an absolute scale. This calibrated technique provides accurate estimates of μs' over a wide range ([0.05 - 8] mm(-1)) for a range of d(fib) ([0.2 - 1] mm).
authors.affiliation: Center for Optical Diagnostics and Therapy, Department of Radiation Oncology, Erasmus Medical Center, PO Box 2040, 3000 CA Rotterdam, The Netherlands.
authors.forename: S C
authors.initials: SC
authors.lastname: Kanick
authors.forename: U A
authors.initials: UA
authors.lastname: Gamm
authors.forename: M
authors.initials: M
authors.lastname: Schouten
authors.forename: H J C M
authors.initials: HJ
authors.lastname: Sterenborg
authors.forename: D J
authors.initials: DJ
authors.lastname: Robinson
authors.forename: A
authors.initials: A
authors.lastname: Amelink