title: [Estimation of haplotypes based on DNA pooling].
abstract: DNA pooling, a fast and economic study strategy, is widely used in areas of scientific research. In spite of various limits, researchers are making their efforts to improve DNA pooling toward a more perfect direction, including allele frequency detection and estimation of haplotypes. In haplotype estimation, more and more analyzing Methods originated from the expectation-maximization algorithm have appeared, with improved accuracy and practicality, such as HaploPool algorithm and PoooL algorithm.
authors.affiliation: Department of Epidemiology & Biostatistics, Key Laboratory of Epidemiolog of Ministry of Education, Health Science Center, Peking University, Beijing 100191, China.
authors.forename: Liu
authors.initials: L
authors.lastname: He
authors.forename: Xun
authors.initials: X
authors.lastname: Tang
authors.forename: Yonghua
authors.initials: Y
authors.lastname: Hu
mesh_terms: D000465:Algorithms; D004247:DNA / Q000235:genetics*; D005787:Gene Frequency / Q000235:genetics*; D005788:Gene Pool; D014644:Genetic Variation / Q000235:genetics; D060005:Genotyping Techniques; D006239:Haplotypes / Q000235:genetics*; D006801:Humans
chemical_list: D004247:DNA