title: Role of the lymphatics in cancer metastasis and chemotherapy applications.
abstract: The lymphatic system was first described centuries ago. The recent discovery of various molecular markers has allowed for more in-depth research of the lymphatic system and its role in health and disease. The lymphatic system has recently been elucidated as playing an active role in cancer metastasis. The knowledge of the active processes involved in lymphatic metastasis provides novel treatment targets for various malignancies.
authors.affiliation: University of Kansas Medical Center, 3901 Rainbow Boulevard, Mailstop 2005, Kansas City, Kansas 66160, USA.
authors.forename: Jennifer D
authors.initials: JD
authors.lastname: McAllaster
authors.forename: Mark S
authors.initials: MS
authors.lastname: Cohen
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000494:pharmacology; D015415:Biomarkers / Q000378:metabolism; D016503:Drug Delivery Systems; D006801:Humans; D042583:Lymphangiogenesis; D008207:Lymphatic Metastasis; D008208:Lymphatic System / Q000378:metabolism*; D009369:Neoplasms / Q000188:drug therapy / Q000473:pathology*
chemical_list: D000970:Antineoplastic Agents; D015415:Biomarkers