title: A review of some epidemiological studies on cancer risk from low-dose radiation or other carcinogenic agents.
abstract: It is extremely difficult to assess cancer risks accurately due to health effects of low-dose radiation exposure or other carcinogens based on epidemiological studies. For the detection of minute increases of the risk at low-level exposure, most of epidemiological studies lack statistical power, and they involve various complicated confounding factors. This paper reports on a literature survey of epidemiological studies published since 2000 on cancer risks associated with low-dose radiation and other carcinogens to gather major epidemiological data. Integrated risk indices were derived from those data by using, where possible, statistical models. Regarding risk assessment of low-dose radiation exposure, it is important to lower the degree of uncertainty arising from risk estimation. Risk assessment of low-dose radiation exposure could be scientific evidence when uncertainty is considered in comparing carcinogenic risks of radiation with those of other carcinogens.
authors.affiliation: Center for Information Research, National Institute of Public Health, 2-3-6 Minami, Wako, Saitama 351-0197, Japan. ogata@niph.go.jp
authors.forename: Hiromitsu
authors.initials: H
authors.lastname: Ogata
mesh_terms: D002273:Carcinogens / Q000494:pharmacology*; D002986:Clinical Trials as Topic; D016021:Epidemiologic Studies; D006801:Humans; D009381:Neoplasms, Radiation-Induced / Q000453:epidemiology* / Q000209:etiology*; D011829:Radiation Dosage
chemical_list: D002273:Carcinogens