title: Primary anaplastic solitary fibrous tumor of the tentorium cerebelli.
abstract: Meningeal solitary fibrous tumors (MSFT) have been described in about 80 patients as benign spindle-cell neoplasms, with few anaplastic variants. We report a 57-year-old male patient with a 4-month history of progressive headache caused by a primary anaplastic MSFT arising from the tentorium cerebelli. MRI revealed a tentorium-based tumor that extended into the occipital lobe superiorly and into the cerebellum inferiorly on the left. Following gross total resection of the tumor and postoperative radiotherapy, the patient experienced symptomatic improvement with no recurrence at the 12-month follow-up. The final tumor pathology was consistent with an anaplastic MSFT, with a Ki-67 proliferative index of 25%.
authors.affiliation: Department of Neurosurgery, The Affiliated Hospital of Medical College, Qingdao University, 16 Jiangsu Road, Qingdao 266003, China.
authors.forename: Peng
authors.initials: P
authors.lastname: Sun
authors.forename: Zhao-jian
authors.initials: ZJ
authors.lastname: Li
authors.forename: Cheng-qin
authors.initials: CQ
authors.lastname: Wang
authors.forename: Yu-jun
authors.initials: YJ
authors.lastname: Li
authors.forename: Xin-sheng
authors.initials: XS
authors.lastname: Yang
authors.forename: Wen-shuai
authors.initials: WS
authors.lastname: Deng
mesh_terms: D000071443:12E7 Antigen; D015703:Antigens, CD / Q000378:metabolism; D018952:Antigens, CD34 / Q000378:metabolism; D015815:Cell Adhesion Molecules / Q000378:metabolism; D002531:Cerebellum / Q000473:pathology*; D004388:Dura Mater / Q000473:pathology*; D005500:Follow-Up Studies; D006261:Headache / Q000209:etiology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D019253:Proto-Oncogene Proteins c-bcl-2 / Q000378:metabolism; D054364:Solitary Fibrous Tumors / Q000150:complications / Q000473:pathology*; D014057:Tomography, X-Ray Computed
chemical_list: D000071443:12E7 Antigen; D015703:Antigens, CD; D018952:Antigens, CD34; C061828:CD99 protein, human; D015815:Cell Adhesion Molecules; D019253:Proto-Oncogene Proteins c-bcl-2