title: Structure and absolute configuration of helosides A and B, new saponins from Chamaelirium luteum.
abstract: Investigation of Chamaelirium luteum roots led to the isolation of two new steroidal saponins, helosides A and B, that contain a previously unreported aglycone, helogenin. Their structures and absolute configuration were elucidated through MS-MS, NMR, chemical degradation, and X-ray crystallography.
authors.affiliation: School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane 4072, Australia.
authors.forename: Victoria L
authors.initials: VL
authors.lastname: Challinor
authors.forename: Julia M U
authors.initials: JM
authors.lastname: Stuthe
authors.forename: Paul V
authors.initials: PV
authors.lastname: Bernhardt
authors.forename: Reginald P
authors.initials: RP
authors.lastname: Lehmann
authors.forename: William
authors.initials: W
authors.lastname: Kitching
authors.forename: James J
authors.initials: JJ
authors.lastname: De Voss
mesh_terms: D018360:Crystallography, X-Ray; D019668:Liliaceae / Q000737:chemistry*; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D018517:Plant Roots / Q000737:chemistry; D012503:Saponins / Q000737:chemistry / Q000302:isolation & purification*
chemical_list: D012503:Saponins; C561338:heloside A; C561339:heloside B