title: Cobalt toxicity--an emerging clinical problem in patients with metal-on-metal hip prostheses?
abstract: We report two Australian patients with possible cobalt toxicity related to metal-on-metal total hip replacements. Both patients were treated for osteoarthritis with a DePuy ASR (articular surface replacement) XL Acetabular Hip System prosthesis, which contains cobalt and chromium, and which has recently been recalled from the market.
authors.affiliation: Second Xiangya Hospital of Central South University, Changsha, Hunan, China. r.crawford@qut.edu.au.
authors.forename: Xinzhan
authors.initials: X
authors.lastname: Mao
authors.forename: Andrew A
authors.initials: AA
authors.lastname: Wong
authors.forename: Ross W
authors.initials: RW
authors.lastname: Crawford
mesh_terms: D000368:Aged; D003035:Cobalt / Q000633:toxicity*; D005260:Female; D006622:Hip Prosthesis / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011475:Prosthesis Failure / Q000009:adverse effects
chemical_list: D003035:Cobalt