title: Rapid methods for the isolation of actinides Sr, Tc and Po from raw urine.
abstract: Rapid methods for the isolation and analysis of individual actinides (Th, U, Pu, Am/Cm) and Sr, Tc and Po from small volumes of raw urine have been developed. The methods involve acidification of the sample and the addition of aluminum nitrate or aluminum chloride salting-out agent prior to isolation of the desired analyte using a tandem combination of prefilter material and extraction chromatographic resin. The method has been applied to the separation of individual analytes from spiked urine samples. Analytes were recovered in high yield and radionuclide purity with separation times as low as 30 min. The chemistry employed is compatible with automation on the ARSIIe instrument.
authors.affiliation: PG Research Foundation, Inc., Lisle, IL 60532, USA. dmcalister@pgrf.com
authors.forename: Daniel R
authors.initials: DR
authors.lastname: McAlister
authors.forename: E Philip
authors.initials: EP
authors.lastname: Horwitz
authors.forename: James T
authors.initials: JT
authors.lastname: Harvey
mesh_terms: D008671:Actinoid Series Elements / Q000302:isolation & purification / Q000652:urine; D000077410:Aluminum Chloride; D017607:Aluminum Compounds / Q000737:chemistry; D001331:Automation / Q000379:methods; D002712:Chlorides / Q000737:chemistry; D002845:Chromatography / Q000379:methods; D006801:Humans; D057230:Limit of Detection; D009566:Nitrates / Q000737:chemistry; D011059:Polonium / Q000302:isolation & purification / Q000652:urine; D011834:Radiation Monitoring / Q000379:methods*; D011868:Radioisotopes / Q000302:isolation & purification* / Q000652:urine; D012117:Resins, Synthetic / Q000737:chemistry; D012588:Scintillation Counting / Q000379:methods; D013324:Strontium / Q000302:isolation & purification / Q000652:urine; D013667:Technetium / Q000302:isolation & purification / Q000652:urine; D013997:Time Factors; D016482:Urinalysis / Q000379:methods*
chemical_list: D008671:Actinoid Series Elements; D017607:Aluminum Compounds; D002712:Chlorides; D009566:Nitrates; D011868:Radioisotopes; D012117:Resins, Synthetic; D000077410:Aluminum Chloride; D013667:Technetium; D011059:Polonium; C050609:aluminum nitrate; D013324:Strontium