title: The FGIN period: electrophysiological studies.
abstract: This historical review of the electrophysiology laboratory complemented the activity of the various research teams at the Fidia Georgetown Institute for the Neurosciences and it was the fulfillment of Dr. Erminio Costa's dream to be able to study the inhibitory and excitatory synapse in the central nervous system. These studies were facilitated by the development of the patch clamp technique that allows the functional testing of several of the biochemical and pharmacological hypotheses. The studies described here were the results of the hard work of all the collaborators involved in the projects that will never forget the passionate and stimulating discussion with Dr Costa during and after the development of these projects.
authors.affiliation: Department of Physiology and Biophysics, Georgetown University Medical Center, room 225 3900 Reservoir Rd, N.W., Washington DC 20057, United States. svicin01@georgetown.edu
authors.forename: Stefano
authors.initials: S
authors.lastname: Vicini
mesh_terms: D000818:Animals; D001921:Brain / Q000378:metabolism; D004594:Electrophysiology / Q000266:history* / Q000379:methods*; D049673:History, 20th Century; D006801:Humans; D016202:N-Methylaspartate / Q000378:metabolism; D009480:Neuropharmacology / Q000266:history* / Q000379:methods*; D018408:Patch-Clamp Techniques / Q000266:history / Q000379:methods; D011284:Pregnenolone / Q000494:pharmacology; D017470:Receptors, Glutamate / Q000378:metabolism; D005680:gamma-Aminobutyric Acid / Q000378:metabolism
chemical_list: D017470:Receptors, Glutamate; D005680:gamma-Aminobutyric Acid; D016202:N-Methylaspartate; D011284:Pregnenolone