title: Smooth muscle myopathy as an underrecognized manifestation of active systemic lupus erythematosus.
abstract: Systemic lupus erythematosus (SLE) is a systemic autoimmune disease with protean manifestations. We here present a case of unexplained diarrhoea and abdominal pain in a patient with SLE. Investigations revealed dilatation of stomach, small bowel and colonic wall, biliary and pancreatic ducts, renal collecting systems and ureters as well as thoracic aorta and major pulmonary arteries, as manifestations of a smooth muscle myopathy that was responsive to immunosuppressive therapy with cyclosporin A.
authors.affiliation: Monash Centre of Inflammatory Diseases, Monash Medical Centre, Melbourne, Victoria, Australia. gene-siew@excite.com
authors.forename: G S
authors.initials: GS
authors.lastname: Ngian
authors.forename: P
authors.initials: P
authors.lastname: Naidoo
authors.forename: E F
authors.initials: EF
authors.lastname: Morand
authors.forename: A Y
authors.initials: AY
authors.lastname: Hoi
mesh_terms: D003937:Diagnosis, Differential; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D008875:Middle Aged; D009130:Muscle, Smooth / Q000473:pathology*; D009135:Muscular Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology
chemical_list: D005938:Glucocorticoids