title: Enteropathy associated T cell lymphoma: common in coeliac disease.
abstract: A 56-year-old male admitted with haematemesis and epigastric pain and severe weight loss on a background of coeliac disease. Computed tomography (CT) abdomen revealed a thickening of the mucosal folds of a short segment of jejunum. He deteriorated and had an exploratory laparotomy and bowel resection with side-side jejojejunal stapled anastomosis and extended right hemicolectomy and ileocolic anastomosis. Histology demonstrated multifocal high-grade malignant T cell lymphoma. Coeliac disease is a very common lifelong disorder. It is associated with osteoporosis, infertility, autoimmune disorders and increased risk of malignancy including an increased risk of non-Hodgkin's lymphoma (NHL) especially of the T cell type. Enteropathy-type T cell lymphoma is associated with a very poor prognosis. There is significant evidence that adherence to a gluten-free diet decreases the risk of developing enteropathy-type T cell lymphoma and helps to prevent development of autoimmune diseases, diabetes mellitus and osteoporosis in patients with coeliac disease.
authors.affiliation: Galway University Hospital, Surgery, Newcastle, Galway, Ireland.
authors.forename: Gabrielle Christina
authors.initials: GC
authors.lastname: Colleran
authors.forename: Kevin Christopher
authors.initials: KC
authors.lastname: Cronin
authors.forename: Mary
authors.initials: M
authors.lastname: Casey
authors.forename: Fadel
authors.initials: F
authors.lastname: Bennani
authors.forename: Iqdam
authors.initials: I
authors.lastname: Tobbia
authors.forename: Kevin
authors.initials: K
authors.lastname: Barry