title: Acylation of Grignard reagents mediated by N-methylpyrrolidone: a remarkable selectivity for the synthesis of ketones.
abstract: An efficient user-friendly method of acylation of Grignard reagents to selectively synthesize ketones is presented, which is assisted by simple amides such as NMP, or DMF. The present chemoselective method tolerates a variety of functional groups such as ketone, ester, nitrile and other functional groups.
authors.affiliation: R. L. Fine Chem, No. 15, KHB Industrial Area, Yelahanka Newtown, Bangalore, 560 106, Karnataka, India.
authors.forename: Maravanhalli Sidde
authors.initials: MS
authors.lastname: Gowda
authors.forename: Sushanth Sudhir
authors.initials: SS
authors.lastname: Pande
authors.forename: Ramesha Andagar
authors.initials: RA
authors.lastname: Ramakrishna
authors.forename: Kandikere Ramaiah
authors.initials: KR
authors.lastname: Prabhu