title: Human genome project and sickle cell disease.
abstract: Sickle cell disease is one of the most common genetic blood disorders in the United States that affects 1 in every 375 African Americans. Sickle cell disease is an inherited condition caused by abnormal hemoglobin in the red blood cells. The Human Genome Project has provided valuable insight and extensive research advances in the understanding of the human genome and sickle cell disease. Significant progress in genetic knowledge has led to an increase in the ability for researchers to map and sequence genes for diagnosis, treatment, and prevention of sickle cell disease and other chronic illnesses. This article explores some of the recent knowledge and advances about sickle cell disease and the Human Genome Project.
authors.affiliation: Social Work Program, Elizabeth City State University, Elizabeth City, North Carolina 27909, USA. bjnorman@mail.ecsu.edu
authors.forename: Brenda J
authors.initials: BJ
authors.lastname: Norman
authors.forename: Sheila D
authors.initials: SD
authors.lastname: Miller
mesh_terms: D000223:Adaptation, Psychological; D000293:Adolescent; D000328:Adult; D000755:Anemia, Sickle Cell / Q000453:epidemiology* / Q000523:psychology; D003430:Cross-Sectional Studies; D005260:Female; D005820:Genetic Testing / Q000379:methods*; D015894:Genome, Human; D007722:Health Knowledge, Attitudes, Practice; D006291:Health Policy; D006306:Health Surveys; D016045:Human Genome Project; D006801:Humans; D008297:Male; D008960:Models, Psychological; D011594:Psychometrics; D012944:Social Support; D012947:Social Work; D013223:Statistics as Topic; D013315:Stress, Psychological; D055815:Young Adult