title: Multicomponent reactions of ammonium thiocyanate, acyl chlorides, alkyl bromides, and enaminones: a facile one-pot synthesis of thiophenes.
abstract: An efficient synthesis of thiophene derivatives is described via one-pot reaction between ammonium thiocyanate, acyl chlorides, α-halocarbonyls, and enaminones under solvent-free conditions at 65 °C. The mild reaction conditions and high yields of the products exhibit the good synthetic advantage of these methods.
authors.affiliation: Department of Chemistry, Qaemshahr Branch, Islamic Azad University, PO Box 163, Qaemshahr, Iran. zshossaini@yahoo.com
authors.forename: Zinatossadat
authors.initials: Z
authors.lastname: Hossaini
authors.forename: Faramarz
authors.initials: F
authors.lastname: Rostami-Charati
authors.forename: Samira
authors.initials: S
authors.lastname: Soltani
authors.forename: Anwar
authors.initials: A
authors.lastname: Mirzaei
authors.forename: Kayhaneh
authors.initials: K
authors.lastname: Berijani
mesh_terms: D000473:Alkanes / Q000737:chemistry*; D000588:Amines / Q000737:chemistry*; D001966:Bromine / Q000737:chemistry*; D060326:Chemistry Techniques, Synthetic / Q000379:methods*; D002713:Chlorine / Q000737:chemistry*; D013861:Thiocyanates / Q000737:chemistry*; D013876:Thiophenes / Q000138:chemical synthesis* / Q000737:chemistry / Q000302:isolation & purification
chemical_list: D000473:Alkanes; D000588:Amines; D013861:Thiocyanates; D013876:Thiophenes; D002713:Chlorine; C026976:thiocyanic acid; D001966:Bromine