title: Premature ovarian failure in a woman with a balanced 15;21 translocation: a case report.
abstract: BACKGROUND
  A case of premature ovarian failure with concomitant findings of Robertsonian translocation between 15 and 21 chromosomes is reported here. The aforementioned karyotypic aberration has not been reported in the context of premature ovarian failure to date.
  
  
  METHODS
  We present a case of premature ovarian failure in a 27-year-old infertile Kurdish Iranian woman with a Robertsonian 15;21 translocation.
  
  
  CONCLUSIONS
  The diagnosis of premature ovarian failure of unknown etiology, but with karyotypic evidence of a balanced autosomal translocation, suggests the possible role of autosomal genes in the pathogenesis of ovarian follicular attrition.
authors.affiliation: Arash University Hospital, Department of Obstetrics & Gynecology, Tehran University of Medical Sciences, Tehran, Iran. afahoss@yahoo.com.
authors.forename: Sayedehafagh
authors.initials: S
authors.lastname: Hosseini
authors.forename: Marzieh
authors.initials: M
authors.lastname: Vahid Dastjerdi
authors.forename: Zahra
authors.initials: Z
authors.lastname: Asgari
authors.forename: Haydeh
authors.initials: H
authors.lastname: Samiee