title: Toward a modern synthesis of immunity: Charles A. Janeway Jr. and the immunologist's dirty little secret.
abstract: This essay chronicles the major theoretical and experimental contributions made by Charles A. Janeway, Jr. (1943-2003), Howard Hughes Medical Institute investigator and Yale Professor of Immunobiology, who established the fundamental role of the innate immune system in the induction of the adaptive arm.
authors.affiliation: Immunobiology Department, Yale School of Medicine, 367 Cedar Street, New Haven, CT 06510, USA. peter.gayed@yale.edu
authors.forename: Peter M
authors.initials: PM
authors.lastname: Gayed
mesh_terms: D000486:Allergy and Immunology / Q000266:history; D003237:Connecticut; D049673:History, 20th Century; D049674:History, 21st Century; D007107:Immune System / Q000276:immunology; D007113:Immunity, Innate / Q000276:immunology*; D014481:United States; D014495:Universities / Q000266:history