title: Catalytic asymmetric conjugate allylation of coumarins.
abstract: A catalytic asymmetric conjugate allylation was successfully developed to synthesize potential pharmacologically active 4-allyl-2-oxochroman skeletons. A dual activation strategy was employed by using N,N'-dioxide-Yb(OTf)(3) to activate coumarins and using (CuOTf)(2)•C(7)H(8) to activate tetraallyltin via transmetalation, respectively. Good yields and enantioselectivities were obtained under mild conditions.
authors.affiliation: Key Laboratory of Green Chemistry & Technology, Ministry of Education, College of Chemistry, Sichuan University, Chengdu 610064, PR China.
authors.forename: Yulong
authors.initials: Y
authors.lastname: Kuang
authors.forename: Xiaohua
authors.initials: X
authors.lastname: Liu
authors.forename: Lu
authors.initials: L
authors.lastname: Chang
authors.forename: Min
authors.initials: M
authors.lastname: Wang
authors.forename: Lili
authors.initials: L
authors.lastname: Lin
authors.forename: Xiaoming
authors.initials: X
authors.lastname: Feng