title: Diagnosis of synchronous isolated splenic metastasis from lung adenocarcinoma: complementary role of FDG PET/CT and diffusion-weighted MRI.
abstract: Isolated splenic metastasis is extremely rare. In this study, we report a case of a 52-year-old man referred for Pancoast Tobias Syndrome by which FDG PET/CT detected an isolated splenic metastasis. Diffusion-weighted MRI confirmed the isolated splenic lesion. A low apparent diffusion coefficient was consistent with a tumor lesion. CT-guided biopsy of both the lesions and histopathologic findings confirmed a lung adenocarcinoma with an isolated splenic metastasis. This case reveals a very rare occurrence of isolated splenic metastases in the context of lung cancer and illustrates the role of multimodality functional imaging for the early detection of uncommon metastasis.
authors.affiliation: Université Paris 13, Service de médecine nucléaire, Hôpital Avicenne, Bobigny, France. michael.soussan@avc.aphp.fr
authors.forename: Michael
authors.initials: M
authors.lastname: Soussan
authors.forename: Gabriel
authors.initials: G
authors.lastname: Pop
authors.forename: Matthieu-John
authors.initials: MJ
authors.lastname: Ouvrier
authors.forename: Alain
authors.initials: A
authors.lastname: Neuman
authors.forename: Pierre
authors.initials: P
authors.lastname: Weinmann
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology*; D000077192:Adenocarcinoma of Lung; D004058:Diffusion; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D049268:Positron-Emission Tomography; D013160:Splenic Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000556:secondary*; D014057:Tomography, X-Ray Computed
chemical_list: D019788:Fluorodeoxyglucose F18