title: Tracheobronchial FDG uptake in primary amyloidosis detected by PET/CT.
abstract: Tracheobronchial amyloidosis is a rare manifestation of the disease and has never been described with FDG PET/CT. In this study, we report a case of a 70-year-old man with increasing dyspnea, a right pleural effusion, a tracheobronchial circumferential wall thickening, and a mediastinal fat infiltration on CT scan. FDG PET/CT revealed intense tracheobronchial uptake associated with mediastinal and intra-abdominal fat uptake. Bronchoscopy and mediastinoscopy with biopsies confirmed the diagnosis of primary amyloidosis and excluded malignancy. FDG PET/CT could be useful for the evaluation of tracheobronchial amyloidosis metabolic activity and follow-up.
authors.affiliation: Nuclear Medicine Department, Avicenne Hospital, Assistance Publique-Hôpitaux de Paris, Université Paris 13, Bobigny, France. michael.soussan@avc.aphp.fr
authors.forename: Michael
authors.initials: M
authors.lastname: Soussan
authors.forename: Matthieu-John
authors.initials: MJ
authors.lastname: Ouvrier
authors.forename: Gabriel
authors.initials: G
authors.lastname: Pop
authors.forename: Jean-Louis
authors.initials: JL
authors.lastname: Galas
authors.forename: Alain
authors.initials: A
authors.lastname: Neuman
authors.forename: Pierre
authors.initials: P
authors.lastname: Weinmann
mesh_terms: D000368:Aged; D000686:Amyloidosis / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000378:metabolism*; D001692:Biological Transport; D001980:Bronchi / Q000000981:diagnostic imaging / Q000378:metabolism*; D001995:Bronchography; D019788:Fluorodeoxyglucose F18 / Q000378:metabolism*; D006801:Humans; D000075363:Immunoglobulin Light-chain Amyloidosis; D008297:Male; D049268:Positron-Emission Tomography; D014057:Tomography, X-Ray Computed; D014132:Trachea / Q000000981:diagnostic imaging / Q000378:metabolism*
chemical_list: D019788:Fluorodeoxyglucose F18