title: Consensus statement on indications for anti-angiogenic therapy in the management of corneal diseases associated with neovascularisation: outcome of an expert roundtable.
abstract: The cornea is the clear window at the front of the eye and is the eye's main refractive medium. Its transparency is essential for vision. Corneal neovascularisation is a common clinical problem with serious consequences for vision; it can compromise corneal transparency and plays a major role in corneal graft rejection by breaching corneal immune privilege. In this review, we formulate a consensus on the unmet medical needs in the management of corneal neovascularisation and outline a framework for the clinical research that is needed to identify suitable agents to meet these needs.
authors.affiliation: Department of Ophthalmology, University of Cologne, Joseph-Stelzmann Strasse 9. 50924, Cologne, Germany. claus.cursiefen@uk-koeln.de
authors.forename: Claus
authors.initials: C
authors.lastname: Cursiefen
authors.forename: Joseph
authors.initials: J
authors.lastname: Colin
authors.forename: Reza
authors.initials: R
authors.lastname: Dana
authors.forename: Manuel
authors.initials: M
authors.lastname: Diaz-Llopis
authors.forename: Lana A
authors.initials: LA
authors.lastname: Faraj
authors.forename: Salvador
authors.initials: S
authors.lastname: Garcia-Delpech
authors.forename: Gerd
authors.initials: G
authors.lastname: Geerling
authors.forename: Francis W
authors.initials: FW
authors.lastname: Price
authors.forename: Lies
authors.initials: L
authors.lastname: Remeijer
authors.forename: Barry T
authors.initials: BT
authors.lastname: Rouse
authors.forename: Berthold
authors.initials: B
authors.lastname: Seitz
authors.forename: Patricia
authors.initials: P
authors.lastname: Udaondo
authors.forename: Daniel
authors.initials: D
authors.lastname: Meller
authors.forename: Harminder
authors.initials: H
authors.lastname: Dua
mesh_terms: D020533:Angiogenesis Inhibitors / Q000627:therapeutic use*; D003316:Corneal Diseases / Q000188:drug therapy*; D016510:Corneal Neovascularization / Q000188:drug therapy*; D006801:Humans; D009885:Ophthalmology / Q000592:standards*; D017410:Practice Guidelines as Topic
chemical_list: D020533:Angiogenesis Inhibitors