title: Acquired left ventricular submitral aneurysms in the course of Takayasu arteritis in a child.
abstract: A 9-year-old black African boy was hospitalized for heart failure revealing a severe left ventricular dysfunction associated with dilated cardiomyopathy, two submitral aneurysms, occlusion of the circumflex artery and a giant coronary artery aneurysm on the proximal left anterior descending artery. The boy was coinfected with human immunodeficiency virus and Mycobacterium tuberculosis. Though rare, association of Takayasu arteritis and submitral aneurysm leads to rethinking the pathogenesis of submitral aneurysm and suggests that some of them may be acquired. In our case, a common inflammatory process, possibly triggered by tuberculosis or HIV, may underlie Takayasu and submitral aneurysms.
authors.affiliation: Département de Cardiologie et Maladies Vasculaires, Centre Cardio-pneumologique, Hôpital Pontchaillou,Centre Hospitalier Universitaire de Rennes, 2 rue Henri Le Guilloux, Rennes cedex 09, France. :alban.baruteau@wanadoo.fr
authors.forename: Alban-Elouen
authors.initials: AE
authors.lastname: Baruteau
authors.forename: Raphaël Pedro
authors.initials: RP
authors.lastname: Martins
authors.forename: Dominique
authors.initials: D
authors.lastname: Boulmier
authors.forename: Adeline
authors.initials: A
authors.lastname: Basquin
authors.forename: David
authors.initials: D
authors.lastname: Briard
authors.forename: Virginie
authors.initials: V
authors.lastname: Gandemer
authors.forename: Jean-Marc
authors.initials: JM
authors.lastname: Schleich
mesh_terms: D002648:Child; D060085:Coinfection; D004452:Echocardiography; D015658:HIV Infections / Q000150:complications*; D006322:Heart Aneurysm / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D006352:Heart Ventricles; D006801:Humans; D008297:Male; D009169:Mycobacterium tuberculosis / Q000302:isolation & purification; D013625:Takayasu Arteritis / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D014376:Tuberculosis / Q000150:complications* / Q000382:microbiology; D018608:Ultrasonography, Doppler