title: The Y chromosome in the era of intracytoplasmic sperm injection: a personal review.
abstract: The Y chromosome contains 60 multicopy genes composed of nine different gene families concentrated in regions of multiple repeat sequences called amplicons arranged in mirror images called palindromes. This pattern is susceptible to deletions caused by homologous recombination with itself, and can explain the presence of small numbers of sperm in otherwise azoospermic men.
authors.affiliation: Infertility Center of St. Louis, St. Luke's Hospital, St. Louis, Missouri 63017, USA. silber@infertile.com
authors.forename: Sherman J
authors.initials: SJ
authors.lastname: Silber
mesh_terms: D000818:Animals; D053713:Azoospermia / Q000235:genetics / Q000503:physiopathology / Q000628:therapy*; D002872:Chromosome Deletion; D041322:Chromosomes, Human, Y; D005260:Female; D020022:Genetic Predisposition to Disease; D040941:Heredity; D015186:Hominidae; D006801:Humans; D008297:Male; D010641:Phenotype; D011247:Pregnancy; D011995:Recombination, Genetic; D013076:Sperm Count; D020554:Sperm Injections, Intracytoplasmic; D013091:Spermatogenesis / Q000235:genetics*