title: Occlusal caries prevention in high and low risk schoolchildren. A clinical trial.
abstract: OBJECTIVE
  To evaluate the caries-preventive effect of a resin-modified glass-ionomer cement used as occlusal sealant (Vitremer) compared with fluoride varnish (Duraphat) application on occlusal surfaces of permanent first molars (OSPFM) in 6-8 year-old schoolchildren (n=268) at high (HR) and low (LR) caries risk.
  
  
  METHODS
  The children were followed-up for 24 months after being systematically allocated into six groups as follows: Control Groups HRC and LRC: children receiving oral health education (OHE) every 3 months; Groups HRV and LRV: children receiving OHE plus varnish application biannually; and Groups HRS and LRS: children receiving OHE plus a single sealant application . The baseline and follow-up examinations were performed by the same calibrated dentist under natural light, using CPI probes and mirrors, after toothbrushing and air-drying. The DMFS was used to record dental caries, in addition to the detection of initial lesions (IL). Data analysis was performed with two primary outcome measures: DMF and DMF+ IL on the OSPFM.
  
  
  RESULTS
  After 24 months, only the HRS group showed statistically lower DMF and DMF+IL increments on OSPFM compared with HRC group. HRV group did not differ from HRC and HRS groups. For LR groups, no statistical difference (P> 0.05) was observed among the treatments.
authors.affiliation: Department of Community Dentistry, Piracicaba Dental School, University of Campinas, Piracicaba, Brazil.
authors.forename: Elaine Pereira da Silva
authors.initials: EP
authors.lastname: Tagliaferro
authors.forename: Vanessa
authors.initials: V
authors.lastname: Pardi
authors.forename: Gláucia Maria Bovi
authors.initials: GM
authors.lastname: Ambrosano
authors.forename: Marcelo de Castro
authors.initials: Mde C
authors.lastname: Meneghim
authors.forename: Silvio Rocha Corrêa
authors.initials: SR
authors.lastname: da Silva
authors.forename: Antonio Carlos
authors.initials: AC
authors.lastname: Pereira
mesh_terms: D002327:Cariostatic Agents; D002648:Child; D003188:Composite Resins; D004245:DMF Index; D003731:Dental Caries / Q000517:prevention & control*; D004311:Double-Blind Method; D005260:Female; D005460:Fluorides, Topical; D005899:Glass Ionomer Cements; D006267:Health Education, Dental; D006801:Humans; D008297:Male; D008963:Molar; D010895:Pit and Fissure Sealants; D012306:Risk; D012969:Sodium Fluoride; D018709:Statistics, Nonparametric
chemical_list: D002327:Cariostatic Agents; D003188:Composite Resins; D005460:Fluorides, Topical; D005899:Glass Ionomer Cements; D010895:Pit and Fissure Sealants; C084550:Vitremer; C023807:sodium fluoride topical preparation; D012969:Sodium Fluoride