title: Effects of Zn(II) complex with vitamins C and U, and carnitine on metabolic syndrome model rats.
abstract: The insulinomimetic activity of a Zn(ii) complex is reported. The effects of the Zn(ii) complex with ascorbic acid (Vitamin C; VC), methylmethionine sulfonium chloride (Vitamin U; VU) and l-carnitine were assessed in diet-induced metabolic syndrome model rats. Zn(VU)(2)Cl(2) and Zn(VC)Cl(2) were suggested to be useful supplementary materials for preventing metabolic syndrome by reducing visceral adipose tissues or accelerating blood fluidity.
authors.affiliation: Department of Sports, Health and Nutrition, Faculty of Health and Welfare, 4-7-2 Minatoji, Nakamachi, Kobe, Japan. kinuyo.m@suma.kobe-wu.ac.jp
authors.forename: Kinuyo
authors.initials: K
authors.lastname: Matsumoto
authors.forename: Nao
authors.initials: N
authors.lastname: Motoyasu
authors.forename: Kyoko
authors.initials: K
authors.lastname: Sera
authors.forename: Takako
authors.initials: T
authors.lastname: Fujii
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Yoshikawa
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Yasui
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Taniguchi
authors.forename: Naemi
authors.initials: N
authors.lastname: Kajiwara
mesh_terms: D017667:Adipocytes / Q000187:drug effects / Q000378:metabolism; D000273:Adipose Tissue / Q000187:drug effects / Q000378:metabolism / Q000473:pathology; D000818:Animals; D001205:Ascorbic Acid / Q000494:pharmacology / Q000627:therapeutic use*; D001835:Body Weight / Q000187:drug effects; D002331:Carnitine / Q000494:pharmacology / Q000627:therapeutic use*; D002469:Cell Separation; D004032:Diet; D004195:Disease Models, Animal; D005227:Fatty Acids / Q000378:metabolism; D005247:Feeding Behavior / Q000187:drug effects; D005947:Glucose / Q000494:pharmacology; D020128:Inhibitory Concentration 50; D007328:Insulin / Q000031:analogs & derivatives; D024821:Metabolic Syndrome / Q000188:drug therapy* / Q000517:prevention & control; D051381:Rats; D014814:Vitamin U / Q000494:pharmacology / Q000627:therapeutic use*; D015032:Zinc / Q000494:pharmacology / Q000627:therapeutic use*
chemical_list: D005227:Fatty Acids; D007328:Insulin; D014814:Vitamin U; D005947:Glucose; D015032:Zinc; D001205:Ascorbic Acid; D002331:Carnitine