title: Morphologic characteristics of retinal arterial macroaneurysm and its regression pattern on spectral-domain optical coherence tomography.
abstract: OBJECTIVE
  To investigate morphologic characteristics of retinal arterial macroaneurysm (RAM) and its regression pattern using spectral-domain optical coherence tomography.
  
  
  METHODS
  This observational case series included six eyes of six patients with RAM. All patients had undergone repeated comprehensive ophthalmologic examination, including measurement of best-corrected visual acuity, slit-lamp biomicroscopy, indirect fundus examination, fundus photography, fluorescein angiography, and spectral-domain optical coherence tomography (Spectralis OCT). Morphologic findings of RAM on spectral-domain optical coherence tomography and changes after treatment were investigated.
  
  
  RESULTS
  On initial diagnosis, eyes with RAMs showed a round hyperreflective wall with a hyporeflective lumen on spectral-domain optical coherence tomography. Five of six patients underwent direct laser photocoagulation to the RAM. One hour after treatment, the lumen of the RAM showed a homogeneous high reflectance, indicating occlusion with thrombus. One or 2 months after treatment, spectral-domain optical coherence tomography demonstrated almost entirely obliterated RAMs and decreased perianeurysmal retinal edema. One patient showed spontaneous rupture and involution of RAM. Superficial location of RAM was associated with hemorrhagic complications.
  
  
  CONCLUSIONS
  Spectral-domain optical coherence tomography can show morphologic characteristics of RAM and structural changes after treatment. These new findings can be valuable not only in clinical diagnosis but also in predicting the treatment response of RAM.
authors.affiliation: Department of Ophthalmology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.
authors.forename: Eun Kyoung
authors.initials: EK
authors.lastname: Lee
authors.forename: Se Joon
authors.initials: SJ
authors.lastname: Woo
authors.forename: Jeeyun
authors.initials: J
authors.lastname: Ahn
authors.forename: Kyu Hyung
authors.initials: KH
authors.lastname: Park
mesh_terms: D000328:Adult; D000369:Aged, 80 and over; D000783:Aneurysm / Q000175:diagnosis* / Q000601:surgery; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D017075:Laser Coagulation; D054018:Lasers, Excimer; D008297:Male; D008875:Middle Aged; D012161:Retinal Artery / Q000473:pathology* / Q000601:surgery; D012164:Retinal Diseases / Q000175:diagnosis* / Q000601:surgery; D012189:Retrospective Studies; D041623:Tomography, Optical Coherence; D016896:Treatment Outcome; D014792:Visual Acuity / Q000502:physiology