title: Surface EMG to assess and quantify upper airway dilators activity during non-invasive ventilation.
abstract: This study tests the hypothesis that the surface electromyographic (EMG) activity of upper airway dilators would respond to inspiratory loading in a healthy humans model of ventilator trigger asynchrony. EMG activity was measured in levator alae-nasi, genioglossus, parasternal, scalene and diaphragm muscles in eight subjects. They breathed quietly through a face mask and then were connected to a mechanical ventilator. Recordings were performed during nasal breathing against negative pressure triggers (-2.5%, -5% and -10% of maximal inspiratory pressure) and during oro-nasal breathing with a "-10% trigger". Scalene, alae-nasi and genioglossus EMG activity level increased with the "-10% trigger". While no breathing route dependence was found in scalene, the significant increase was only found for nasal breathing in alae-nasi and for oro-nasal breathing in genioglossus. The dyspnea intensity was significantly correlated with the EMG activity level of these three muscles. Surface EMG of airway dilator muscles could be used as a complementary tool to assess inspiratory drive during mechanical ventilation.
authors.affiliation: Université Pierre et Marie Curie Paris 6, ER10upmc, Paris F-75006, France. francois.hug@univ-nantes.fr
authors.forename: François
authors.initials: F
authors.lastname: Hug
authors.forename: Mathieu
authors.initials: M
authors.lastname: Raux
authors.forename: Capucine
authors.initials: C
authors.lastname: Morelot-Panzini
authors.forename: Thomas
authors.initials: T
authors.lastname: Similowski
mesh_terms: D000328:Adult; D004576:Electromyography / Q000295:instrumentation / Q000379:methods*; D005260:Female; D006801:Humans; D017214:Laryngeal Masks; D008297:Male; D012121:Respiration, Artificial / Q000295:instrumentation / Q000379:methods*; D015656:Respiratory Mechanics / Q000502:physiology*; D012132:Respiratory Muscles / Q000502:physiology*; D055815:Young Adult