title: Rhodium-catalyzed anti-Markovnikov addition of secondary amines to arylacetylenes at room temperature.
abstract: An efficient method for synthesis of E-enamines by the anti-Markovnikov addition of secondary amines to terminal alkynes is described. The reaction of a variety of aryl- and heteroarylacetylenes proceeded at room temperature using a combination of a 8-quinolinolato rhodium complex and P(p-MeOC(6)H(4))(3) as a catalyst. The products were obtained as enamines by simple bulb-to-bulb distillation.
authors.affiliation: Department of Chemistry, Faculty of Science and Technology, Keio University, 3-14-1 Hiyoshi, Yokohama, Kanagawa 223-8522, Japan.
authors.forename: Kazunori
authors.initials: K
authors.lastname: Sakai
authors.forename: Takuya
authors.initials: T
authors.lastname: Kochi
authors.forename: Fumitoshi
authors.initials: F
authors.lastname: Kakiuchi