title: On the evolution rate in mammalian mitochondrial genomes.
abstract: The methods of phylogenetic inference have become more and more realistic and effective since the evolution rate was taken into account. In order to study the evolution rate more comprehensively, all 13 protein coding genes in 123 mammalian mitochondrial genomes are analyzed. The evolution rates of different codon position are analyzed as well. The evolution rate is estimated by Shannon entropy. We find that the distribution of 3rd codon position doesn't follow gamma distribution and the results suggest that it follows a mixed distribution of gamma distribution and normal distribution. The relationship between different codon positions is also studied. We find that there are significant positive correlation between three codon positions. Especially between 1st codon position and 2nd codon position, there is strong linear relationship.
authors.affiliation: School of Mathematical Sciences, Nankai University, Tianjin, China.
authors.forename: Gang
authors.initials: G
authors.lastname: Hu
authors.forename: Shiyi
authors.initials: S
authors.lastname: Shen
authors.forename: Kui
authors.initials: K
authors.lastname: Wang
mesh_terms: D000818:Animals; D003062:Codon / Q000235:genetics; D019295:Computational Biology; D019143:Evolution, Molecular; D054629:Genome, Mitochondrial / Q000235:genetics*; D010802:Phylogeny; D011506:Proteins / Q000235:genetics
chemical_list: D003062:Codon; D011506:Proteins