title: Incidence and prognosis of stroke in young adults: a population-based study in Ferrara, Italy.
abstract: The reported annual incidence of juvenile stroke ranges from 9 to 47 cases per 100,000 inhabitants. We sought to estimate the incidence of first-ever stroke in young adults through a population-based stroke registry in a well-defined and stable population. We planned to collect all cases of new stroke in people aged 15-44 years in Ferrara, Italy, over the period 2002-2007. During the surveillance period, a first-ever stroke was diagnosed in 39 patients, giving a mean annual crude incidence rate of 12.1 cases per 100,000 person-years (95% CI 8.6-16.5), 9.1 when adjusted to the European population. The overall 30-day case fatality rate was 7.7, 21.4% for hemorrhagic stroke. The incidence rate was in the range of estimates detected in western countries. The case-fatality rate was lower than that reported in less recent studies. The stroke subtype predicted the probability of death and the outcome.
authors.affiliation: Section of Clinical Neurology, Department of Medical and Surgical Sciences of Communication and Behaviour, University of Ferrara, Corso della Giovecca 203, 44121 Ferrara, Italy.
authors.forename: Elisabetta
authors.initials: E
authors.lastname: Groppo
authors.forename: Riccardo
authors.initials: R
authors.lastname: De Gennaro
authors.forename: Gino
authors.initials: G
authors.lastname: Granieri
authors.forename: Patrik
authors.initials: P
authors.lastname: Fazio
authors.forename: Edward
authors.initials: E
authors.lastname: Cesnik
authors.forename: Enrico
authors.initials: E
authors.lastname: Granieri
authors.forename: Ilaria
authors.initials: I
authors.lastname: Casetta
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D015994:Incidence; D007558:Italy / Q000453:epidemiology; D008297:Male; D011379:Prognosis; D012042:Registries; D020521:Stroke / Q000175:diagnosis* / Q000453:epidemiology*