title: Pathologic basis for abnormal uterine bleeding with organic uterine pathologies.
abstract: Research is ongoing into the mechanisms of abnormal uterine bleeding, including bleeding from organic etiologies, where there is an intrinsic uterine lesion. Most of the current studies are focused on abnormalities of angiogenesis. By elucidating these mechanisms, targeted therapies can be developed. This article reviews the literature on pathologic mechanisms involved in bleeding from organic etiologies.
authors.affiliation: Department of Pathology, UH/E158, UMDNJ-New Jersey Medical School, 185 South Orange Ave., Newark, NJ 07103, USA. hellerds@umdnj.edu
authors.forename: Debra S
authors.initials: DS
authors.lastname: Heller
mesh_terms: D005260:Female; D006801:Humans; D008796:Metrorrhagia / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D014591:Uterine Diseases / Q000473:pathology*