title: NOD so fast: NLRX1 puts the brake on inflammation.
abstract: In this issue of Immunity, Allen et al. (2011) and Xia et al. (2011) provide in vivo and biochemical evidence that NLRX1, a member of the nucleotide binding domain and leucine-rich-repeat-containing protein family, functions as a negative regulator of RIG-I and Toll-like receptors.
authors.affiliation: Department of Microbiology, Immunology and Molecular Genetics, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA.
authors.forename: Kislay
authors.initials: K
authors.lastname: Parvatiyar
authors.forename: Genhong
authors.initials: G
authors.lastname: Cheng