title: Water Soluble Star-block Copolypeptides: Towards Biodegradable Nanocarriers for Versatile and Simultaneous Encapsulation.
abstract: The synthesis of water soluble star-block copolypeptides and their encapsulation properties are described. The star-block copolypeptides, obtained by ring-opening polymerization of amino acid N-carboxyanhydrides, consist of a PEI core, a hydrophobic polyphenylalanine or polyleucine inner shell, and a negatively charged polyglutamate outer shell. The encapsulation study showed that these water soluble, amphiphilic star-block copolypeptides could simultaneously encapsulate versatile compounds ranging from hydrophobic to anionic and cationic hydrophilic guest molecules.
authors.affiliation: Medical College, Shantou University, Xinling Road 22, Shantou 515041, P. R. China.
authors.forename: Wensheng
authors.initials: W
authors.lastname: Zhuang
authors.forename: Lihui
authors.initials: L
authors.lastname: Liao
authors.forename: Heru
authors.initials: H
authors.lastname: Chen
authors.forename: Jinzhi
authors.initials: J
authors.lastname: Wang
authors.forename: Ying
authors.initials: Y
authors.lastname: Pan
authors.forename: Lumian
authors.initials: L
authors.lastname: Zhang
authors.forename: Daojun
authors.initials: D
authors.lastname: Liu