title: Comparison of immediate renal dysfunction in split and partial liver transplantation versus full size liver transplantation in Shiraz transplant centre.
abstract: BACKGROUND
  Renal dysfunction (RD) is a common complication following liver transplantation. Postoperative renal function after split liver transplant (SLT) and (partial living related liver transplant) (LRLT) has not been well studied yet.
  
  
  METHODS
  Renal function immediately after surgery was analyzed retrospectively in 32 patients that received SLT and LRLT. Serum creatinine (SCr) was measured before surgery, and, after transplantation daily during the first week and at 14, 21, and 28 days after transplantation. Patient's medical records were reviewed to find clinical data;Model for end-stage liver disease (MELD) score, Child-Turcotte-Pugh score (CTP) class, the length of surgery, length of anhepatic phase, hospital and ICU admission, incidence of acute rejection, renal dysfunction, and sepsis. These data compared between groups.
  
  
  RESULTS
  Length of surgery and anhepatic phase was longer in SLT and LRLT group (P<0.05). The incidence of acute rejection, reoperation, and complication such as sepsis was higher in SLT and LRLT group than FSLT group (P<0.05). There were no significant difference between groups with respect to MELD, CTP score, the need for transfusions, the length of admission to the hospital and ICU. Immunosuppression regimens were similar in both groups. RD developed in 25.8% of SLT and LRLT patients, but in only 9.5% of FSLT patients (p=0.063). The requirement for RRT in SLT and LRLT group (12.5%) was greater than that in the FSLT group (2.3%); P=0.20.
  
  
  CONCLUSIONS
  Although the number of patients studied was small, our data suggests a higher incidence of RD in patients receiving SLT and LRLT.
authors.affiliation: Transplant Research Centre, Shiraz University of Medical Sciences, Iran.
authors.forename: Mohammad Mahdi
authors.initials: MM
authors.lastname: Sagheb
authors.forename: Maryam
authors.initials: M
authors.lastname: Sharifian
authors.forename: Saghar
authors.initials: S
authors.lastname: Ahmadi
authors.forename: Maryam
authors.initials: M
authors.lastname: Moini
authors.forename: Ghanbar-Ali
authors.initials: GA
authors.lastname: Rais-Jalali
authors.forename: Saeed
authors.initials: S
authors.lastname: Behzadi
authors.forename: Jamshid
authors.initials: J
authors.lastname: Roozbeh
authors.forename: Hamed
authors.initials: H
authors.lastname: Jalaian
authors.forename: Saman
authors.initials: S
authors.lastname: Nikeghbalian
authors.forename: Ali
authors.initials: A
authors.lastname: Bahador
authors.forename: Heshmatolah
authors.initials: H
authors.lastname: Salahi
authors.forename: Mehdi
authors.initials: M
authors.lastname: Salehipoor
authors.forename: Koroush
authors.initials: K
authors.lastname: Kazemi
authors.forename: Seyed Ali
authors.initials: SA
authors.lastname: Malek-Hosseini
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D003404:Creatinine / Q000097:blood; D005260:Female; D006085:Graft Survival; D006801:Humans; D007668:Kidney / Q000503:physiopathology*; D007677:Kidney Function Tests; D016031:Liver Transplantation / Q000009:adverse effects* / Q000379:methods*; D019520:Living Donors; D008297:Male; D012189:Retrospective Studies
chemical_list: D003404:Creatinine