title: Pregnancy concomitant with metastatic adult granulosa cell tumor.
abstract: BACKGROUND
  Metastatic adult granulosa cell tumor of the ovary is rarely encountered with pregnancy.
  
  
  RESULTS
  Primigravida (26 years) presented at 20 weeks of gestation with acute abdomen and clinical evidence of supraclavicular lymphadenopathy and ascites. She was diagnosed of adult granulosa cell tumor (AGCT) of the right ovary following right salpingoophrectomy done 1 month prior to conception. Fine needle aspiration cytology of supraclavicular lymph node, revealed it to be a metastatic AGCT. Chemotherapy was given antepartum and she delivered a healthy preterm baby at 30 weeks. Subsequently, she had optimal debulking surgery following 6 cycles of cisplatin-based chemotherapy. Baby at 10 months of age was with normal milestones.
  
  
  CONCLUSIONS
  The case is an unusual presentation of metastatic adult granulosa cell tumor at child bearing age. Although rapidly progressing, successful prolongation of pregnancy till 30 weeks of gestation was possible with the judicious use of chemotherapy. Fetal and maternal outcomes were favorable.
authors.affiliation: Department of Obstetrics and Gynaecology, UCMS and GTB Hospital, Delhi, India. rachna_anila@yahoo.co.in
authors.forename: R
authors.initials: R
authors.lastname: Agarwal
authors.forename: G
authors.initials: G
authors.lastname: Radhakrishnan
authors.forename: A G
authors.initials: AG
authors.lastname: Radhika
authors.forename: J
authors.initials: J
authors.lastname: Jain
authors.forename: S
authors.initials: S
authors.lastname: Sharma
authors.forename: H
authors.initials: H
authors.lastname: Srivastava
mesh_terms: D000328:Adult; D005260:Female; D006106:Granulosa Cell Tumor / Q000175:diagnosis / Q000188:drug therapy* / Q000556:secondary* / Q000601:surgery; D006801:Humans; D050498:Live Birth; D008207:Lymphatic Metastasis; D010051:Ovarian Neoplasms / Q000175:diagnosis / Q000188:drug therapy* / Q000556:secondary* / Q000601:surgery; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000175:diagnosis / Q000188:drug therapy* / Q000601:surgery; D047928:Premature Birth