title: Granulomatous response due to anabolic steroid injections.
abstract: Injected corticosteroids can sometimes lead to a granulomatous reaction. This is apparently also true for anabolic steroids, which are often used by bodybuilders, although we have not found any histologic report on such a phenomenon. We report a case of a granulomatous reaction in a 30-year-old male bodybuilder having undergone anabolic steroid injections. Foreign bodies typical of steroids were found, together with areas of calcification and ossification with lamellar bone. Multivacuolated macrophages were found in the fibrous tissue close to these areas of calcification and ossification.
authors.affiliation: Service of Cellular Pathology, Clinica Ponferrada, Spain. gpyauflowerlion@terra.es
authors.forename: Angel
authors.initials: A
authors.lastname: Fernandez-Flores
authors.forename: Saul
authors.initials: S
authors.lastname: Valerdiz
authors.forename: Luis G
authors.initials: LG
authors.lastname: Crespo
authors.forename: Ramon
authors.initials: R
authors.lastname: Rodriguez
mesh_terms: D000328:Adult; D045930:Anabolic Agents / Q000008:administration & dosage / Q000009:adverse effects*; D001707:Biopsy, Needle; D004300:Doping in Sports; D005500:Follow-Up Studies; D015745:Granuloma, Foreign-Body / Q000139:chemically induced* / Q000473:pathology; D006801:Humans; D007150:Immunohistochemistry; D007273:Injections, Intramuscular; D008297:Male; D018570:Risk Assessment; D012871:Skin Diseases / Q000139:chemically induced* / Q000473:pathology; D013256:Steroids / Q000008:administration & dosage / Q000009:adverse effects*; D014891:Weight Lifting
chemical_list: D045930:Anabolic Agents; D013256:Steroids