title: Coronary stent use in New York State in the drug-eluting stent era.
abstract: OBJECTIVE
  The drug-eluting stent (DES) was perceived as a revolutionary medical technology because of the lower risk of restenosis compared with bare metal stent (BMS). However, the safety of DES use was called into question in 2006 due to increased incidence of catastrophic late stent thrombosis. This study aims to describe coronary stent use in the DES era in New York State.
  
  
  METHODS
  Using New York State statewide hospital discharge database, we conducted descriptive analysis and logistic regression to examine the independent impacts of the introduction of DES and of the DES safety concern on DES utilization, controlling for patient demographics, co-morbidities and hospital effects.
  
  
  RESULTS
  In the first year following the introduction of DES technology, there was a 10-fold increase in the odds of DES use versus BMS use (AOR: 10.86, 95% CI: 9.84-11.99, P < 0.001). When the safety of DES use was called into question, the odds of DES utilization decreased by 75% over a 9-month period (AOR: 0.23, 95% CI: 0.20-0.26, P < 0.001).
  
  
  CONCLUSIONS
  Following the introduction of DES, there was a rapid adoption of DES by interventional cardiologists, followed by a rapid abandonment of DES when significant safety issues were raised. After the safety of DES was called into question, there was a reduction in the use of DES and in the use of stents in general.
authors.affiliation: Department of Anesthesiology, University of Rochester, Rochester, NY 14642, USA. feng_qian@urmc.rochester.edu
authors.forename: Feng
authors.initials: F
authors.lastname: Qian
authors.forename: Edward L
authors.initials: EL
authors.lastname: Hannan
authors.forename: Laurent G
authors.initials: LG
authors.lastname: Glance
authors.forename: Charles E
authors.initials: CE
authors.lastname: Phelps
authors.forename: Frederick S
authors.initials: FS
authors.lastname: Ling
authors.forename: Peter J
authors.initials: PJ
authors.lastname: Veazie
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002318:Cardiovascular Diseases / Q000601:surgery*; D016208:Databases, Factual; D054855:Drug-Eluting Stents / Q000706:statistics & numerical data*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009518:New York; D010351:Patient Discharge