title: A portable pressure pump for microfluidic lab-on-a-chip systems using a porous polydimethylsiloxane (PDMS) sponge.
abstract: In this paper, we propose a novel portable and disposable pressure pump using a porous polydimethylsiloxane (PDMS) sponge and demonstrate its application to a microfluidic lab-on-a-chip. The porous PDMS sponge was simply fabricated by a sugar leaching technique based on capillary suction of pre-cured PDMS into lumps of sugar, thereby enabling us to achieve the porous PDMS sponge composed of interconnected micropores. To indicate the characteristics of the porous PDMS sponge and pump, we measured the average porosities of them whose values were 0.64 and 0.34, respectively. A stress-strain relationship of the fabricated portable pressure pump represented a linear behavior in the compressive strain range of 0 to 20%. Within this range, a pumping volume of the pressure pump could be linearly controlled by the compressed strain. Finally, the fabricated porous PDMS pump was successfully demonstrated as a portable pressure pump for a disposable microfluidic lab-on-a-chip for efficient detection of agglutination. The proposed portable pressure pump can be potentially applicable to various disposable microfluidic lab-on-a-chip systems.
authors.affiliation: Department of Mechanical Engineering, Pohang University of Science and Technology, San 31 Hyoja-dong Nam-gu, Pohang 790-784, Korea.
authors.forename: Kyoung Je
authors.initials: KJ
authors.lastname: Cha
authors.forename: Dong Sung
authors.initials: DS
authors.lastname: Kim
mesh_terms: D004129:Dimethylpolysiloxanes / Q000737:chemistry; D004867:Equipment Design; D056656:Lab-On-A-Chip Devices; D044085:Microfluidics / Q000295:instrumentation*; D016062:Porosity
chemical_list: D004129:Dimethylpolysiloxanes