title: Fertility sparing surgery for ovarian tumors in children and young adults.
abstract: OBJECTIVE
  To study the outcome of fertility conserving surgery for ovarian tumors in children and young adults (≤ 20 years) over 6 years (2003-2009).
  
  
  METHODS
  This prospective study included 183 patients diagnosed with ovarian cysts or tumors requiring surgical excision. Ovarian cystectomy/ovariectomy was carried out followed by frozen section histopathology. Malignant cases were subjected to staging laparotomy and fertility sparing surgery.
  
  
  RESULTS
  The median age at diagnosis was 17 years (range 7-20 years). 160/183 (87.4%) were non-neoplastic ovarian cysts or benign tumors. In 131/160 (81.8%) of non-neoplastic and benign tumors, it was possible to preserve the affected ovary. Twenty cases (11%) were diagnosed as primary malignant ovarian tumors, 2/183 (1.1%) were borderline tumors and 1 case (0.55%) was metastatic colonic carcinoma. The median follow up of cases with primary malignant ovarian tumors was 36 months. During this period, two recurrences (9.1%) were detected, both of the germ cell type (immature teratoma and yolk sac tumor). Recurrent cases were managed by local excision and lymph node sampling followed by chemotherapy.
  
  
  CONCLUSIONS
  Fertility sparing surgery for malignant ovarian tumors in children and young adults has excellent prognosis and should be attempted whenever possible.
authors.affiliation: Department of Obstetrics and Gynecology, Mansoura University, Mansoura, Egypt. elsaidhady@yahoo.co.uk
authors.forename: El-Said
authors.initials: el-S
authors.lastname: Abdel-Hady
authors.forename: Reda
authors.initials: R
authors.lastname: Abdel-Hady Hemida
authors.forename: Anas
authors.initials: A
authors.lastname: Gamal
authors.forename: Maged
authors.initials: M
authors.lastname: El-Shamey
mesh_terms: D000293:Adolescent; D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001761:Bleomycin / Q000627:therapeutic use; D016190:Carboplatin / Q000008:administration & dosage; D017024:Chemotherapy, Adjuvant; D002648:Child; D002945:Cisplatin / Q000627:therapeutic use; D005047:Etoposide / Q000627:therapeutic use; D005260:Female; D059247:Fertility Preservation; D006801:Humans; D009364:Neoplasm Recurrence, Local / Q000628:therapy*; D009367:Neoplasm Staging; D059351:Organ Sparing Treatments; D010048:Ovarian Cysts / Q000601:surgery*; D010051:Ovarian Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery*; D010052:Ovariectomy; D017239:Paclitaxel / Q000008:administration & dosage; D011446:Prospective Studies; D055815:Young Adult
chemical_list: D001761:Bleomycin; D005047:Etoposide; D016190:Carboplatin; D017239:Paclitaxel; D002945:Cisplatin