title: A study of performance on microarray data sets for a classifier based on information theoretic learning.
abstract: Gene-expression microarray is a novel technology that allows the examination of tens of thousands of genes at a time. For this reason, manual observation is not feasible and machine learning methods are progressing to face these new data. Specifically, since the number of genes is very high, feature selection methods have proven valuable to deal with these unbalanced-high dimensionality and low cardinality-data sets. In this work, the FVQIT (Frontier Vector Quantization using Information Theory) classifier is employed to classify twelve DNA gene-expression microarray data sets of different kinds of cancer. A comparative study with other well-known classifiers is performed. The proposed approach shows competitive results outperforming all other classifiers.
authors.affiliation: Department of Computer Science, Facultade de Informática, Campus de Elviña s/n, University of A Coruña, Spain. iporto@udc.es
authors.forename: Iago
authors.initials: I
authors.lastname: Porto-Díaz
authors.forename: Verónica
authors.initials: V
authors.lastname: Bolón-Canedo
authors.forename: Amparo
authors.initials: A
authors.lastname: Alonso-Betanzos
authors.forename: Oscar
authors.initials: O
authors.lastname: Fontenla-Romero
mesh_terms: D000465:Algorithms; D001185:Artificial Intelligence; D004273:DNA, Neoplasm / Q000235:genetics; D030541:Databases, Genetic; D019277:Entropy; D017143:Fuzzy Logic; D006801:Humans; D007257:Information Theory; D046228:Microarray Analysis / Q000145:classification* / Q000379:methods; D008957:Models, Genetic; D015233:Models, Statistical; D015203:Reproducibility of Results; D012984:Software
chemical_list: D004273:DNA, Neoplasm