title: Labeling strategies with F-18 for positron emission tomography imaging.
abstract: The labeling of probes with fluorine-18 [(18)F, β(+); 96.7%] continues to play a considerably important role in the development of positron emission tomography (PET) as a modality for both clinical research and clinical diagnoses. This review summarizes the strategies and recent developments in the fluorine-18 labeling of probes for PET imaging. Problems and issues relating to the practical production of fluorine-18 currently in widespread use are also discussed.
authors.affiliation: Department of Pathology, the Third Xiangya Hospital, Central South University, Changsha, P R China.
authors.forename: Yonghong
authors.initials: Y
authors.lastname: Gu
authors.forename: Dong
authors.initials: D
authors.lastname: Huang
authors.forename: Zhiguo
authors.initials: Z
authors.lastname: Liu
authors.forename: Jiaguo
authors.initials: J
authors.lastname: Huang
authors.forename: Wenbin
authors.initials: W
authors.lastname: Zeng
mesh_terms: D000818:Animals; D005462:Fluorine Radioisotopes / Q000737:chemistry; D006801:Humans; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals / Q000138:chemical synthesis / Q000737:chemistry
chemical_list: D005462:Fluorine Radioisotopes; D019275:Radiopharmaceuticals