title: Reversal of drug-induced rhabdomyolysis on bone scan.
abstract: A 75-year-old man with prostate cancer was referred for metastatic workup. A Tc-99m methylene diphosphonate bone scan was performed which revealed diffusely increased radiopharmaceutical uptake in the muscles of the arms and thighs. The patient was taking simvastatin 80 mg per day and gemfibrozil 600 mg twice a day for high cholesterol. The patient reported myalgias, and laboratory evaluation was consistent with rhabdomyolysis. After discontinuation of the anticholesterol medications, the clinical and laboratory evaluations normalized. Bone scan performed 1 year later demonstrated complete resolution of muscle uptake.
authors.affiliation: Department of Radiology, Nuclear Medicine Section, NYU Langone Medical Center, New York, NY, USA.
authors.forename: Joseph
authors.initials: J
authors.lastname: Abrams
authors.forename: Serafin
authors.initials: S
authors.lastname: Tiu
mesh_terms: D000368:Aged; D001859:Bone Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary; D001842:Bone and Bones / Q000000981:diagnostic imaging*; D005189:False Positive Reactions; D006801:Humans; D008297:Male; D011471:Prostatic Neoplasms / Q000473:pathology; D011877:Radionuclide Imaging; D012206:Rhabdomyolysis / Q000139:chemically induced* / Q000000981:diagnostic imaging*