title: Short-term temporal alterations in magnetic resonance signal occur in primary lesions identified in the deep digital flexor tendon of the equine digit.
abstract: BACKGROUND
  Primary lesions of the deep digital flexor tendon (DDFT) within the digit are an important cause of lameness diagnosed using magnetic resonance imaging (MRI) but appearance of these lesions over time has not been documented.
  
  
  OBJECTIVE
  To determine whether the magnetic resonance (MR) appearance of different primary DDFT lesions alter over a 6 month period and whether lesion type is a determinant of these changes.
  
  
  METHODS
  Cases included had lameness attributable to a primary lesion involving the DDFT in the digit diagnosed on MRI. Lesions were typed into parasagittal, dorsal border and core lesions. Approximate volumes and intensities were quantified for each lesion type using T2* scan sequences. Follow-up examinations and measurements were repeated at 3 and 6 month periods following conservative management.
  
  
  RESULTS
  Twenty-three horses fitted the inclusion criteria. Lesion distribution included: parasagittal (n = 7), dorsal border (n = 11) and core lesions (n = 5). No association was found between age of horse, degree of lameness and lesion type. Only dorsal border lesions showed statistically significant reduction both in volume (initial scan: 0.18 ± 0.14 cm(3) ) at 3 months (0.11 ± 0.10 cm(3) , P<0.05) and 6 months (0.05 ± 0.05 cm(3) , P<0.01) and ratiometric intensity (initial scan: 4.06 ± 1.54) at 6 months (2.00 ± 0.43; P<0.01). Parasagittal and core lesions showed no difference in lesion volume or ratiometric intensity. Lameness improved in all lesion types following conservative management.
  
  
  CONCLUSIONS
  Dorsal border lesions of the DDFT show reduction in both volume and intensity whereas parasagittal and core lesions do not.
  
  
  CONCLUSIONS
  Lesion typing may be important in predicting lesion behaviour and short-term outcome using MR imaging.
authors.affiliation: Musculoskeletal Biology, Faculty of Health and Life Sciences, University of Liverpool, Leahurst Campus Nottingham Trent University. Burton Street, Nottingham, UK. p.i.milner@liverpool.ac.uk
authors.forename: P I
authors.initials: PI
authors.lastname: Milner
authors.forename: S
authors.initials: S
authors.lastname: Sidwell
authors.forename: A M
authors.initials: AM
authors.lastname: Talbot
authors.forename: P D
authors.initials: PD
authors.lastname: Clegg
mesh_terms: D000818:Animals; D005260:Female; D005552:Forelimb / Q000473:pathology; D006734:Horse Diseases / Q000175:diagnosis* / Q000473:pathology; D006736:Horses; D008279:Magnetic Resonance Imaging / Q000662:veterinary*; D008297:Male; D013708:Tendon Injuries / Q000473:pathology / Q000662:veterinary*; D013710:Tendons / Q000473:pathology; D013997:Time Factors