title: Pituitary FDG uptake in a patient of lung cancer with bilateral adrenal metastases causing adrenal cortical insufficiency.
abstract: A 64-year-old woman with history of lung cancer and left adrenal gland metastasis was referred for FDG PET/CT to assess the response to target therapy and local radiotherapy treatment. In addition to bilateral adrenal gland FDG uptake lesions, the PET/CT also showed focal FDG uptake in pituitary gland with standardized uptake value of 3.9. Adrenocorticotropic hormone serum level was 439 pg/mL (normal <46 pg/mL), and serum cortisol level was 6 μg/dL (normal range, 5-25 μg/dL). The image and serum test results suggested the diagnosis of lung cancer, with bilateral adrenal metastases causing adrenal cortical insufficiency with secondary pituitary gland hyperplasia.
authors.affiliation: Department of Nuclear Medicine, Chung Shan Medical University Hospital, Taichung, Taiwan.
authors.forename: Jui-Hung
authors.initials: JH
authors.lastname: Weng
authors.forename: Jong-Kang
authors.initials: JK
authors.lastname: Lee
authors.forename: Ming-Fang
authors.initials: MF
authors.lastname: Wu
authors.forename: Chao-Yu
authors.initials: CY
authors.lastname: Shen
authors.forename: Pan-Fu
authors.initials: PF
authors.lastname: Kao
mesh_terms: D000310:Adrenal Gland Neoplasms / Q000150:complications* / Q000556:secondary*; D000309:Adrenal Insufficiency / Q000000981:diagnostic imaging / Q000209:etiology* / Q000378:metabolism*; D001692:Biological Transport; D005260:Female; D019788:Fluorodeoxyglucose F18 / Q000378:metabolism*; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology*; D008875:Middle Aged; D010902:Pituitary Gland / Q000000981:diagnostic imaging / Q000378:metabolism*; D049268:Positron-Emission Tomography; D014057:Tomography, X-Ray Computed
chemical_list: D019788:Fluorodeoxyglucose F18