title: Determination of cyantraniliprole and its major metabolite residues in vegetable and soil using ultra-performance liquid chromatography/tandem mass spectrometry.
abstract: A rapid, highly sensitive and selective method was developed for the determination of the cyantraniliprole and its major metabolite J9Z38 in cucumber, tomato and soil by ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS). Target compounds were extracted with acetonitrile and an aliquot cleaned with primary and secondary amine. Two pairs of precursor product ion transitions for cyantraniliprole and J9Z38 were measured and evaluated. Average recoveries for cucumber, tomato and soil at three levels (10, 50 and 100 µg/kg) ranged from 74.7 to 96.2% with intra-day relative standard deviation (RSD) of 2.6-15.1% and inter-day RSD of 3.4-13.3%. The limit of quantitation for cyantraniliprole and J9Z38 were determined to be 5 and 10 µg/kg in samples (cucumber, tomato and soil), respectively. This method was used to determine the cyantraniliprole and J9Z38 residues in real cucumber, tomato and soil samples for studies on their dissipation. The trial results showed that the half-lives of cyantraniliprole obtained after treatments were 2.2, 2.8 and 9.5 days in cucumber, tomato and soil in Zhejiang, respectively, and that the average levels of cyantraniliprole and J9Z38 residues in cucumber and tomato were all <0.01 mg/kg with the interval of 10 days after treatment.
authors.affiliation: Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Key Laboratory of Pesticide Chemistry and Application, Ministry of Agriculture, Beijing, 100193, China.
authors.forename: Fengshou
authors.initials: F
authors.lastname: Dong
authors.forename: Xingang
authors.initials: X
authors.lastname: Liu
authors.forename: Jun
authors.initials: J
authors.lastname: Xu
authors.forename: Jing
authors.initials: J
authors.lastname: Li
authors.forename: Yuanbo
authors.initials: Y
authors.lastname: Li
authors.forename: Weili
authors.initials: W
authors.lastname: Shan
authors.forename: Wencheng
authors.initials: W
authors.lastname: Song
authors.forename: Yongquan
authors.initials: Y
authors.lastname: Zheng
mesh_terms: D002853:Chromatography, Liquid / Q000379:methods*; D007306:Insecticides / Q000032:analysis* / Q000378:metabolism; D057230:Limit of Detection; D011720:Pyrazoles / Q000032:analysis*; D015203:Reproducibility of Results; D012989:Soil Pollutants / Q000032:analysis*; D021241:Spectrometry, Mass, Electrospray Ionization / Q000379:methods*; D053719:Tandem Mass Spectrometry / Q000379:methods*; D014675:Vegetables / Q000737:chemistry*; D062367:ortho-Aminobenzoates / Q000032:analysis*
chemical_list: D007306:Insecticides; D011720:Pyrazoles; D012989:Soil Pollutants; D062367:ortho-Aminobenzoates; C558219:cyantraniliprole