title: Impaired event memory and recollection in a case of developmental amnesia.
abstract: A current debate in the literature is whether all declarative memories and associated memory processes rely on the same neural substrate. Here, we show that H.C., a developmental amnesic person with selective bilateral hippocampal volume loss, has a mild deficit in personal episodic memory, and a more pronounced deficit in public event memory; semantic memory for personal and general knowledge was unimpaired. This was accompanied by a subtle difference in impairment between recollection and familiarity on lab-based tests of recognition memory. Strikingly, H.C.'s recognition did not benefit from a levels-of-processing manipulation. Thus, not all types of declarative memory and related processes can exist independently of the hippocampus even if it is damaged early in life.
authors.affiliation: Department of Psychology, York University, Toronto, Canada. shaynar@yorku.ca
authors.forename: R S
authors.initials: RS
authors.lastname: Rosenbaum
authors.forename: N
authors.initials: N
authors.lastname: Carson
authors.forename: N
authors.initials: N
authors.lastname: Abraham
authors.forename: B
authors.initials: B
authors.lastname: Bowles
authors.forename: D
authors.initials: D
authors.lastname: Kwan
authors.forename: S
authors.initials: S
authors.lastname: Köhler
authors.forename: E
authors.initials: E
authors.lastname: Svoboda
authors.forename: B
authors.initials: B
authors.lastname: Levine
authors.forename: B
authors.initials: B
authors.lastname: Richards
mesh_terms: D000647:Amnesia / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008568:Memory / Q000502:physiology*; D011939:Mental Recall / Q000502:physiology*; D009483:Neuropsychological Tests; D012372:ROC Curve; D055815:Young Adult