title: Gastroesophageal Reflux and Body Movement in Infants: Investigations with Combined Impedance-pH and Synchronized Video Recording.
abstract: The aim of this paper was to investigate the temporal association of gastroesophageal reflux (GER) and body movement in infants. GER were registered by combined impedance-pH, documentation of body movement was done by video. Videorecording time (Vt) was divided into "resting time" and "movement time" and analyzed for occurrence of GER. Association was defined as movement 1 minute before/after the beginning of a GER. Statistical evaluation was by Fisher's exact test. In 15 infants, 341 GER were documented during Vt (86 hours). 336 GER (99%) were associated with movement, only 5 episodes (1%) occured during resting time. Movement was significantly associated with the occurrence of GER (P < .0001). There is a strong temporal association between GER and body movement in infants. However, a clear distinction between cause and effect could not be made with the chosen study design. Combined impedance-pH has proven to be the ideal technique for this approach.
authors.affiliation: Klinik für Kinder-und Jugendmedizin, Universitätsklinikum der RWTH Aachen, Pauwelsstraße 30, 52074 Aachen, Germany.
authors.forename: Tobias G
authors.initials: TG
authors.lastname: Wenzl
authors.forename: Olaf
authors.initials: O
authors.lastname: Stoltenburg
authors.forename: Jiri
authors.initials: J
authors.lastname: Silny
authors.forename: Heino
authors.initials: H
authors.lastname: Skopnik