title: Acquired central hypothyroidism in a male thalassaemic patient with severe iron overload.
abstract: Acquired central hypothyroidism (CH) is a rare form of hypothyroidism that results from a variety of conditions affecting the hypothalamus and the pituitary gland. This pathology remains difficult to diagnose in patients with chronic disease. The Authors describe a 21-year-old patient with thalassaemia (TM) who was referred for the evaluation of short stature and hypogonadism, and was found to have CH.This case report stresses the importance of following thyroid function in TM patients and underlines the criteria for diagnosis and treatment.
authors.affiliation: Quisisana Hospital,Via Paolo V, 25 44121, Ferrara, Italy. vdesanctis@libero.it
authors.forename: Vincenzo
authors.initials: V
authors.lastname: De Sanctis
authors.forename: Michela
authors.initials: M
authors.lastname: Giovannini
mesh_terms: D017809:Fatal Outcome; D006801:Humans; D007037:Hypothyroidism / Q000209:etiology* / Q000378:metabolism; D019190:Iron Overload / Q000150:complications* / Q000378:metabolism; D008297:Male; D012720:Severity of Illness Index; D055815:Young Adult; D017086:beta-Thalassemia / Q000150:complications* / Q000378:metabolism