title: Contribution of the 2-[18F]-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography to the diagnosis of primary osseous Hodgkin lymphoma.
abstract: Hodgkin lymphoma typically presents as a nodal lesion and infrequently involves extra nodal sites. Although cases of primary extra-nodal Hodgkin lymphoma have been reported previously, the reality of the primitive nature of the disease was difficult to authenticate with traditional high resolution imaging techniques, such as computed tomography or magnetic resonance imaging, because they cannot evaluate the spread of the disease throughout the whole body. We report here a case of primary osseous Hodgkin lymphoma, regarded as stage I extranodal IE thanks to the important contribution of a new imaging technique, the 2-[18F]-fluoro-2-deoxy-d-glucose positron emission tomography/ computed tomography (18F-FDG-PET/CT). PET enables systemic Hodgkin lymphoma with secondary bone invasion to be distinguished from primitive osseous Hodgkin lymphoma. This technique is highly specific in demonstrating the isolated osseous localisation of the tumour and should be recommended in all patients with putative osseous lymphoma.
authors.affiliation: Centre Hospitalier Universitaire de Purpan, Anatomie et Cytologie Pathologiques, Place du Docteur Baylac, Toulouse, 31059, France.
authors.forename: Florence
authors.initials: F
authors.lastname: Breibach
authors.forename: Anne
authors.initials: A
authors.lastname: Julian
authors.forename: Camille
authors.initials: C
authors.lastname: Laurent
authors.forename: Eric
authors.initials: E
authors.lastname: Anglade
authors.forename: Arnaud
authors.initials: A
authors.lastname: Constantin
authors.forename: Nicolas
authors.initials: N
authors.lastname: Sans
authors.forename: Jean-Louis
authors.initials: JL
authors.lastname: Tricoire
authors.forename: Pierre
authors.initials: P
authors.lastname: Brousset
authors.forename: Marie-Bernadette
authors.initials: MB
authors.lastname: Delisle
authors.forename: Anne
authors.initials: A
authors.lastname: Gomez-Brouchet