title: The economic cost to households of childhood malaria in Papua New Guinea: a focus on intra-country variation.
abstract: BACKGROUND
  We compare direct and indirect household costs associated with malaria treatment for children<3 years in two provinces of Papua New Guinea. In particular, we explore the role of uncertainty around mean household costs and whether assuming a normal distribution for household costs limits the accuracy of any direct cost comparisons.
  
  
  METHODS
  Exit surveys were undertaken at inpatient and outpatient health facilities. In order to handle uncertainty and facilitate comparisons, parametric and non-parametric bootstrap methods were used to estimate direct and indirect costs at the individual data level. The inpatient and outpatient incremental costs from Madang and Maprik health facilities were compared and significant differences between provinces were identified.
  
  
  RESULTS
  Differences were noted between provinces for both inpatient and outpatient household costs. Total arithmetic mean costs for an outpatient malaria episode were US$7.54 in Madang and US$9.20 in Maprik. Total mean inpatient malaria episode costs were US$25.20 in Madang and US$14.08 in Maprik. As cost distributions were not normal, non-parametric bootstrap techniques were used for cost comparisons. Total household costs per outpatient episode of malaria were lower, although not significantly, in Maprik than in Madang (incremental cost of US$ -1.67; 95% CI -4.16, 0.31), while total household costs per inpatient episode were significantly higher in Madang than in Maprik (difference of US$11.16; 95% CI 5.47, 25.33). A difference was noted between provinces in the proportion of indirect costs in total household costs for an outpatient visit: 76% in Madang vs 94% in Maprik. The proportion for indirect costs associated with inpatient visits varied less: 63% in Madang vs 68% in Maprik.
  
  
  CONCLUSIONS
  Intra-country differences need to be considered in estimating household costs for both outpatient and inpatient malaria treatment. Our findings suggest that it is important to recognize the impact of both direct and indirect costs on individuals' capacity to afford treatment. Certain indirect costs are difficult to measure accurately, particularly respondents' interpretations of their productive versus non-productive time. Despite this, exploring intra-country cost variation can provide important information to health policy makers.
authors.affiliation: Barcelona Centre for International Health Research, CRESIB, Hospital Clínic-Universitat de Barcelona, C/Rosselló 132, 4 Floor, 08036 Barcelona, Spain. elisa.sicuri@cresib.cat
authors.forename: Elisa
authors.initials: E
authors.lastname: Sicuri
authors.forename: Carol
authors.initials: C
authors.lastname: Davy
authors.forename: Marcella
authors.initials: M
authors.lastname: Marinelli
authors.forename: Olive
authors.initials: O
authors.lastname: Oa
authors.forename: Maria
authors.initials: M
authors.lastname: Ome
authors.forename: Peter
authors.initials: P
authors.lastname: Siba
authors.forename: Lesong
authors.initials: L
authors.lastname: Conteh
authors.forename: Ivo
authors.initials: I
authors.lastname: Mueller
mesh_terms: D002675:Child, Preschool; D017281:Cost of Illness; D005191:Family Characteristics; D005260:Female; D006801:Humans; D007223:Infant; D008288:Malaria / Q000191:economics*; D008297:Male; D010219:Papua New Guinea; D011795:Surveys and Questionnaires