title: A case of secondary glaucoma due to bilateral anterior chamber shallowing caused by Marfan's syndrome.
abstract: OBJECTIVE
  To report the clinical manifestations and treatment of a case of secondary glaucoma evolving from bilateral anterior chamber flattening caused by Marfan's syndrome.
  
  
  METHODS
  The ophthalmic and systemic features, B-scan and UBM characteristics were recorded. Therapy and efficacy were analyzed.
  
  
  RESULTS
  Marfan's syndrome, in this case, caused bilateral iris-lens diaphragm anterior dislocation, anterior chamber flattening, pupillary block, angle closure, and finally resulted in persistent increased intraocular pressure (IOP). After undergoing pars plana vitrectomy and lensectomy combined with anterior chamber reformation, the visual acuity of the patient's right eye increased from 6/150 to 6/7.5 (best-corrected) and that of the left eye was improved from 6/100 to 6/10 (best-corrected). The IOP of the right eye fell to 18 mmHg, and the left eye to 12 mmHg.
  
  
  CONCLUSIONS
  Marfan's syndrome can cause bilateral anterior chambers flattening, and induce secondary angle closure glaucoma. Combined pars plana vitrectomy, lensectomy and anterior chamberplasty can re-form the anterior chamber, control IOP and maintain visual function.
authors.affiliation: State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, China.
authors.forename: Chengguo
authors.initials: C
authors.lastname: Zuo
authors.forename: Fenfen
authors.initials: F
authors.lastname: Yu
authors.forename: Mei
authors.initials: M
authors.lastname: Li
authors.forename: Yi
authors.initials: Y
authors.lastname: Sun
authors.forename: Xing
authors.initials: X
authors.lastname: Liu
mesh_terms: D000867:Anterior Chamber; D005901:Glaucoma / Q000209:etiology; D015812:Glaucoma, Angle-Closure / Q000209:etiology*; D006801:Humans; D007429:Intraocular Pressure; D007498:Iris; D007906:Lens Subluxation / Q000209:etiology*; D008382:Marfan Syndrome / Q000150:complications*; D009798:Ocular Hypertension / Q000209:etiology*; D014792:Visual Acuity; D014821:Vitrectomy