title: Going paperless: implementing an electronic laboratory notebook in a bioanalytical laboratory.
abstract: AIT Bioscience, a bioanalytical CRO, implemented a highly configurable, Oracle-based electronic laboratory notebook (ELN) from IDBS called E-WorkBook Suite (EWBS). This ELN provides a high degree of connectivity with other databases, including Watson LIMS. Significant planning and training, along with considerable design effort and template validation for dozens of laboratory workflows were required prior to EWBS being viable for either R&D or regulated work. Once implemented, EWBS greatly reduced the need for traditional quality review upon experiment completion. Numerous real-time error checks occur automatically when conducting EWBS experiments, preventing the majority of laboratory errors by pointing them out while there is still time to correct any issues. Auditing and reviewing EWBS data are very efficient, because all data are forever securely (and even remotely) accessible, provided a reviewer has appropriate credentials. Use of EWBS significantly increases both data quality and laboratory efficiency.
authors.affiliation: AIT Bioscience, LLC, 2265 Executive Drive, Indianapolis, IN 46241, USA. bbeato@aitbioscience.com
authors.forename: Brian
authors.initials: B
authors.lastname: Beato
authors.forename: April
authors.initials: A
authors.lastname: Pisek
authors.forename: Jessica
authors.initials: J
authors.lastname: White
authors.forename: Timothy
authors.initials: T
authors.lastname: Grever
authors.forename: Brian
authors.initials: B
authors.lastname: Engel
authors.forename: Michael
authors.initials: M
authors.lastname: Pugh
authors.forename: Michael
authors.initials: M
authors.lastname: Schneider
authors.forename: Barbara
authors.initials: B
authors.lastname: Carel
authors.forename: Laurel
authors.initials: L
authors.lastname: Branstrator
authors.forename: Ronald
authors.initials: R
authors.lastname: Shoup
mesh_terms: D002623:Chemistry Techniques, Analytical / Q000379:methods*; D016208:Databases, Factual; D007753:Laboratories; D011996:Records; D012984:Software; D014584:User-Computer Interface