title: [Chemokine profile of Yusho patients].
abstract: Dioxins may have an impact on the human immunological system, which would increase the risk to develop allergic diseases, such as atopic dermatitis. In the present study, we measured serum levels of Th1- and Th2-favored chemokines in 233 Yusho patients who attended annual medical check-ups from 20.06 to 2009 and in 97 control subjects. Serum levels of CCL5, CCL17, and CCL27 in Yusho patients were significantly lower than those in control subjects. In addition, serum levels of some chemokines have weak correlations with blood levels of dioxins in either Yusho patients or control subjects.
authors.affiliation: Research and Clinical Center for Yusho and Dioxin, Kyushu University Hospital, Fukuoka, Japan.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Uchi
authors.forename: Fumiko
authors.initials: F
authors.lastname: Yasukawa
authors.forename: Masutaka
authors.initials: M
authors.lastname: Furue
mesh_terms: D000368:Aged; D054414:Chemokine CCL17 / Q000097:blood; D054425:Chemokine CCL27 / Q000097:blood; D018946:Chemokine CCL5 / Q000097:blood; D018925:Chemokines / Q000097:blood*; D005260:Female; D005506:Food Contamination; D006801:Humans; D008297:Male; D012275:Oryza / Q000506:poisoning*; D010938:Plant Oils / Q000506:poisoning*; D011078:Polychlorinated Biphenyls / Q000506:poisoning*
chemical_list: D054414:Chemokine CCL17; D054425:Chemokine CCL27; D018946:Chemokine CCL5; D018925:Chemokines; D010938:Plant Oils; D011078:Polychlorinated Biphenyls