title: Neuritis ossificans of the tibial, common peroneal and lateral sural cutaneous nerves.
abstract: We describe a 23-year-old woman with neuritis ossificans involving the tibial, common peroneal and lateral sural nerves. She presented with chronic debilitating posterior knee pain. An MRI scan showed masses in these nerves, biopsy of which revealed a histological diagnosis of neuritis ossificans. Treatment with OxyContin and Neurotin for two years resulted in resolution of symptoms. Follow-up MRI demonstrated a resolution of two of the three masses. There was a persistent area of ossification without associated oedema in the common peroneal nerve. Neuritis ossificans has the histological appearance of myositis ossificans and follows a similar clinical course. The success of conservative treatment in this case suggests that the potential complications of surgical excision can be avoided.
authors.affiliation: Department of Diagnostic Radiology, Yale University School of Medicine, 333 Cedar Street, New Haven, Connecticut 06510, USA. lee.katz@yale.edu
authors.forename: L D
authors.initials: LD
authors.lastname: Katz
authors.forename: D
authors.initials: D
authors.lastname: Lindskog
authors.forename: R
authors.initials: R
authors.lastname: Eisen
mesh_terms: D000588:Amines / Q000627:therapeutic use; D000700:Analgesics / Q000627:therapeutic use; D003509:Cyclohexanecarboxylic Acids / Q000627:therapeutic use; D005260:Female; D000077206:Gabapentin; D006801:Humans; D008279:Magnetic Resonance Imaging; D009443:Neuritis / Q000175:diagnosis* / Q000188:drug therapy; D009999:Ossification, Heterotopic / Q000175:diagnosis* / Q000188:drug therapy; D010098:Oxycodone / Q000627:therapeutic use; D010523:Peripheral Nervous System Diseases / Q000175:diagnosis* / Q000188:drug therapy; D010543:Peroneal Nerve / Q000473:pathology; D013497:Sural Nerve / Q000473:pathology; D013979:Tibial Nerve / Q000473:pathology; D055815:Young Adult; D005680:gamma-Aminobutyric Acid / Q000627:therapeutic use
chemical_list: D000588:Amines; D000700:Analgesics; D003509:Cyclohexanecarboxylic Acids; D005680:gamma-Aminobutyric Acid; D000077206:Gabapentin; D010098:Oxycodone