title: Polycystic ovary syndrome is associated with negatively variable impacts on domains of health-related quality of life: evidence from a meta-analysis.
abstract: OBJECTIVE
  To systematically review the literature to identify the impact of polycystic ovary syndrome (PCOS) on specific health-related quality of life domains.
  
  
  METHODS
  Meta-analysis.
  
  
  METHODS
  N/A.
  
  
  METHODS
  The outcomes of 423 patients and 285 controls from 5 articles that used the Short Form 36 (SF-36) questionnaire were used for meta-analysis.
  
  
  METHODS
  N/A.
  
  
  METHODS
  The SF-36 dimensions including physical function, physical role function, body pain, general health, vitality, social function, emotional role function, and mental health were evaluated.
  
  
  RESULTS
  Compared with controls, women with PCOS had lower scores in all SF-36 dimensions: physical function (mean differences [MD], -5.46; 95% confidence intervals [CI], -8.52, -2.41), physical role function (MD, -5.76; 95% CI, -8.49, -3.03), body pain (MD, -4.55; 95% CI, -7.99, -1.11), general health (MD, -11.34; 95% CI, -19.53, -3.15), vitality (MD, -15.14; 95% CI, -17.43, -12.84), social function (MD, -15.95, 95% CI, -18.57, -13.33), emotional role function (MD, -23.86; 95% CI, -27.51, -20.21), and mental health (MD, -13.83; 95% CI, -16.13, -11.53).
  
  
  CONCLUSIONS
  The meta-analysis showed that women with PCOS score lower in each dimension of the SF-36, mostly in the emotional role function.
authors.affiliation: Department of Obstetrics and Gynecology, National Key Laboratory and Unit of Infertility, Clinical Trial Base, First Affiliated Hospital, Heilongjiang University of Chinese Medicine, Harbin, People's Republic of China.
authors.forename: Yanan
authors.initials: Y
authors.lastname: Li
authors.forename: Yan
authors.initials: Y
authors.lastname: Li
authors.forename: Ernest Hung
authors.initials: EH
authors.lastname: Yu Ng
authors.forename: Elisabet
authors.initials: E
authors.lastname: Stener-Victorin
authors.forename: Lihui
authors.initials: L
authors.lastname: Hou
authors.forename: Taixiang
authors.initials: T
authors.lastname: Wu
authors.forename: Fengjuan
authors.initials: F
authors.lastname: Han
authors.forename: Xiaoke
authors.initials: X
authors.lastname: Wu
mesh_terms: D004644:Emotions; D019317:Evidence-Based Medicine; D005260:Female; D006304:Health Status; D006801:Humans; D008603:Mental Health; D010146:Pain / Q000209:etiology / Q000523:psychology; D010147:Pain Measurement; D011085:Polycystic Ovary Syndrome / Q000150:complications / Q000503:physiopathology / Q000523:psychology*; D011788:Quality of Life; D012919:Social Behavior; D011795:Surveys and Questionnaires