title: Heparin-induced thrombocytopenia in cancer.
abstract: Heparin-induced thrombocytopenia is a common and clinically important drug-induced complication that can cause life- and limbthreatening thrombosis. Epidemiologically, the disease has been studied in many different clinical settings, but little is known about it in cancer patients, a population at increased risk for thrombosis and thus exposure to heparin products. Additionally, thrombocytopenia is a common finding in cancer patients. The convergence of these variables highlights the importance of an increased understanding of the disease in cancer patients.
authors.affiliation: Divisions of Hematology, Medical Oncology, and Cellular Therapy, Duke University Medical Center, Durham, North Carolina, USA.
authors.forename: Benjamin J
authors.initials: BJ
authors.lastname: Miriovsky
authors.forename: Thomas L
authors.initials: TL
authors.lastname: Ortel
mesh_terms: D006493:Heparin / Q000009:adverse effects*; D006801:Humans; D009369:Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy; D012306:Risk; D013921:Thrombocytopenia / Q000139:chemically induced* / Q000150:complications* / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy
chemical_list: D006493:Heparin