title: Excessive gestational weight gain in women with gestational and pregestational diabetes.
abstract: We sought to determine the frequency of excessive gestational weight gain (GWG) and its impact on perinatal outcomes in women with gestational (GDM) and pregestational diabetes mellitus (DM). A retrospective cohort of diabetic women was studied. GWG was categorized by the 2009 Institute of Medicine guidelines. Perinatal outcomes were compared between those women with and without excessive GWG. There were 153 women who met study criteria. There was no difference in excessive GWG between women with GDM and pregestational DM (44.4% versus 38.5%,  P = 0.51) or based on White's class ( P = 0.17). After adjusting for confounders, excessive GWG was not associated with an increased rate of adverse perinatal outcomes (odds ratio 1.49, 95% confidence interval 0.56 to 2.35) and had similar associations with both pregestational DM and GDM. Although excessive GWG was common in our diabetic population, it was not associated with an increased rate of adverse perinatal outcomes.
authors.affiliation: Division of Maternal Fetal Medicine, Department of Obstetrics, Gynecology and Reproductive Sciences, University of Texas Health Science Center at Houston, Houston, Texas, USA. benjamin.a.kase@uth.tmc.edu
authors.forename: Benjamin A
authors.initials: BA
authors.lastname: Kase
authors.forename: Clint M
authors.initials: CM
authors.lastname: Cormier
authors.forename: Maged M
authors.initials: MM
authors.lastname: Costantine
authors.forename: Maria
authors.initials: M
authors.lastname: Hutchinson
authors.forename: Susan M
authors.initials: SM
authors.lastname: Ramin
authors.forename: George R
authors.initials: GR
authors.lastname: Saade
authors.forename: Manju
authors.initials: M
authors.lastname: Monga
authors.forename: Sean C
authors.initials: SC
authors.lastname: Blackwell
mesh_terms: D000328:Adult; D016001:Confidence Intervals; D045422:Continuous Positive Airway Pressure; D003924:Diabetes Mellitus, Type 2 / Q000150:complications*; D016640:Diabetes, Gestational / Q000503:physiopathology*; D004420:Dystocia / Q000209:etiology; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007442:Intubation, Intratracheal; D016015:Logistic Models; D016017:Odds Ratio; D010100:Oxygen / Q000627:therapeutic use; D011225:Pre-Eclampsia / Q000209:etiology; D011247:Pregnancy; D011254:Pregnancy in Diabetics / Q000503:physiopathology*; D047928:Premature Birth / Q000209:etiology; D012189:Retrospective Studies; D015430:Weight Gain; D055815:Young Adult
chemical_list: D010100:Oxygen