title: Flavonoids from Lupinus texensis and their free radical scavenging activity.
abstract: Seventeen flavonoids including one new compound were isolated from Texas bluebonnet (Lupinus texensis), the state flower of Texas. Their structures were determined by extensive nuclear magnetic resonance and high-resolution electrospray ionization mass spectrometry analyses. High-performance liquid chromatography analytic method for simultaneous determination of the 17 compounds was established and validated. Eleven isolated flavonoids were first evaluated for their free radical scavenging activity using α,α-diphenyl-β-picrylhydrazyl scavenging assay and they showed activity with EC(50) 48.6-172.5 µg mL(-1).
authors.affiliation: National Center for Pharmaceutical Crops, Arthur Temple College of Forestry and Agriculture, Stephen F. Austin State University, Nacogdoches, Texas 75962-6109, USA.
authors.forename: Zhizhen
authors.initials: Z
authors.lastname: Zhang
authors.forename: Wei
authors.initials: W
authors.lastname: Yuan
authors.forename: Ping
authors.initials: P
authors.lastname: Wang
authors.forename: Greg
authors.initials: G
authors.lastname: Grant
authors.forename: Shiyou
authors.initials: S
authors.lastname: Li
mesh_terms: D001713:Biphenyl Compounds; D002851:Chromatography, High Pressure Liquid; D005419:Flavonoids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D016166:Free Radical Scavengers / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D016014:Linear Models; D031297:Lupinus / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010851:Picrates; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D021241:Spectrometry, Mass, Electrospray Ionization; D013781:Texas
chemical_list: D001713:Biphenyl Compounds; D005419:Flavonoids; D016166:Free Radical Scavengers; D010851:Picrates; D010936:Plant Extracts; C004931:1,1-diphenyl-2-picrylhydrazyl