title: Stem cell-mediated delivery of therapies in the treatment of glioma.
abstract: High grade gliomas can be seldom controlled, due to the infiltrative nature of these tumors and the presence of cell populations resistant to radio- and chemotherapy. Current research aims to develop novel therapeutic approaches to track and eliminate the disseminated glioma-driving cells. Selected delivery of therapeutic agents taking advantage of the tropism of normal stem cells for glioma cells might be one.
authors.affiliation: Molecular Mutagenesis & DNA Repair Unit, Istituto Nazionale Ricerca Cancro, Genova, Italy. guido.frosina@istge.it
authors.forename: G
authors.initials: G
authors.lastname: Frosina
mesh_terms: D000818:Animals; D018014:Gene Transfer Techniques; D015316:Genetic Therapy / Q000379:methods*; D005910:Glioma / Q000473:pathology / Q000628:therapy*; D006801:Humans; D009361:Neoplasm Invasiveness / Q000235:genetics / Q000473:pathology; D013234:Stem Cells / Q000145:classification / Q000166:cytology / Q000502:physiology*; D018523:Tropism