title: Prospects of control and eradication of capripox from the Indian subcontinent: a perspective.
abstract: Sheeppox and goatpox, two endemic capripox infections in India, pose a significant economic threat to small ruminant productivity in the subcontinent. Vaccination of all susceptible sheep and goats is the feasible and sustainable means of control. Availability of effective live attenuated vaccines that are inherently thermostable and development of improved diagnostics provide the opportunities to initiate effective control measures for capripox. All animals older than 4 months can be vaccinated with the current homologous vaccines using a single vaccination by intradermal or subcutaneous routes. The success of the control program needs to be monitored by active surveillance particularly for the presence of virus, as sero-monitoring does not enable the differentiation of infection and vaccination. And also the sero-conversion following capripox vaccination is not detectable enough by the available tools. Sustained control efforts call for socio-economic and political stability, adequate infrastructure and logistic support to store and transport vaccines for reaching out vaccines to the remote end users. Availability of veterinary services, improved extension services for increased awareness among farmers, contribute significantly to the control campaigns. Poor vaccination coverage and in-adequate infrastructure in major parts of the country are some of the major elements that come in the way of effective implementation of building herd immunity through immunization.
authors.affiliation: Division of Virology, Indian Veterinary Research Institute, Mukteswar 263 138, Nainital (Distt.), Uttarakhand, India.
authors.forename: V
authors.initials: V
authors.lastname: Bhanuprakash
authors.forename: M
authors.initials: M
authors.lastname: Hosamani
authors.forename: R K
authors.initials: RK
authors.lastname: Singh
mesh_terms: D000818:Animals; D018151:Capripoxvirus / Q000187:drug effects / Q000502:physiology; D060740:Disease Eradication / Q000191:economics / Q000458:organization & administration; D015511:Goat Diseases / Q000453:epidemiology / Q000276:immunology / Q000517:prevention & control* / Q000635:transmission / Q000821:virology; D006041:Goats / Q000276:immunology / Q000821:virology*; D007194:India; D009934:Organization and Administration; D011057:Politics; D011213:Poxviridae Infections / Q000453:epidemiology / Q000276:immunology / Q000517:prevention & control* / Q000635:transmission / Q000821:virology; D012756:Sheep / Q000276:immunology / Q000821:virology*; D012757:Sheep Diseases / Q000453:epidemiology / Q000276:immunology / Q000517:prevention & control* / Q000635:transmission / Q000821:virology; D012959:Socioeconomic Factors; D014611:Vaccination / Q000662:veterinary; D014613:Vaccines, Attenuated / Q000008:administration & dosage / Q000276:immunology; D014765:Viral Vaccines / Q000008:administration & dosage / Q000276:immunology; D015047:Zoonoses / Q000453:epidemiology / Q000635:transmission / Q000821:virology
chemical_list: D014613:Vaccines, Attenuated; D014765:Viral Vaccines