title: Comparison of optic disc parameters measured by RTVue-100 FDOCT versus HRT-II.
abstract: OBJECTIVE
  To compare optic disc measurements between the new Fourier-domain optical coherence tomography (RTVue-100) and the confocal scanning laser ophthalmoscopy (Heidelberg retinal tomography, HRT-II) in clinical practice.
  
  
  METHODS
  Patients seen from the glaucoma service of an academic department of ophthalmology between August 2008 to August 2009 with good-quality RTVue-100 and HRT-II images within 6 months of each other were included (363 patients were included, 1 eye from each patient). The rim of the optic disc was drawn automatically by RTVue-100 and manually by a single experienced observer for HRT-II. Optic disc measurements from both imaging devices were compared using Bland-Altman plots and the Student t test to assess agreement. The main outcome measure was the agreement in optic disc parameters between the two imaging devices.
  
  
  RESULTS
  Bland-Altman plots indicate significant differences between the RTVue-100 and HRT-II for all optic nerve parameters. The mean HRT-II values were consistently larger than RTVue-100 values for optic disc area and rim area. The RTVue-100 values were larger for the cup area, cup-to-disc area ratio, and vertical and horizontal cup-to-disc ratio. The Student t test showed P<0.001 for averages of all measurements between the two devices.
  
  
  CONCLUSIONS
  We conclude that the disc parameters from these two imaging devices are not interchangeable.
authors.affiliation: Department of Ophthalmology, University of California, San Francisco, CA 94143-0730, USA.
authors.forename: Nisreen K
authors.initials: NK
authors.lastname: Mesiwala
authors.forename: Melike
authors.initials: M
authors.lastname: Pekmezci
authors.forename: Jehn-Yu
authors.initials: JY
authors.lastname: Huang
authors.forename: Travis C
authors.initials: TC
authors.lastname: Porco
authors.forename: Shan C
authors.initials: SC
authors.lastname: Lin
mesh_terms: D003941:Diagnostic Techniques, Ophthalmological / Q000295:instrumentation*; D005260:Female; D005583:Fourier Analysis; D005901:Glaucoma / Q000175:diagnosis*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009798:Ocular Hypertension / Q000175:diagnosis; D019721:Ophthalmoscopes; D009898:Optic Disk / Q000473:pathology*; D009901:Optic Nerve Diseases / Q000175:diagnosis*; D015203:Reproducibility of Results; D041623:Tomography, Optical Coherence / Q000295:instrumentation