title: Oncocytoma of the parotid gland causing false-positive result on I-131 whole-body scintigraphy.
abstract: A 50-year-old patient underwent near-total thyroidectomy in 1997 because of a T₁N₀M₀ follicular carcinoma in the right lobe of the thyroid gland, followed by I-131 ablation (3700 MBq). Follow-up of I-131 whole-body scintigraphy after 9 years showed pathologic uptake at the left side of the neck. Histopathologic analyses of the resected specimen suggested a cystic metastasis within the parotid gland, probably originating from thyroid carcinoma. However, the patient had been disease-free for over 9 years and thyroglobulin was undetectable in plasma. Revision of the specimen with complementary immunohistochemical staining revealed histopathologic aspects more typical of oncocytoma.
authors.affiliation: Department of Radiology and Nuclear Medicine, University Hospital Utrecht, The Netherlands. h.broekhuizen-degast@umcutrecht.nl
authors.forename: Henny
authors.initials: H
authors.lastname: Broekhuizen-de Gast
authors.forename: Hans
authors.initials: H
authors.lastname: van Isselt
authors.forename: Mark
authors.initials: M
authors.lastname: Roef
authors.forename: Marnix
authors.initials: M
authors.lastname: Lam
mesh_terms: D018249:Adenoma, Oxyphilic / Q000000981:diagnostic imaging* / Q000473:pathology / Q000503:physiopathology; D005189:False Positive Reactions; D006801:Humans; D007457:Iodine Radioisotopes; D008875:Middle Aged; D010307:Parotid Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000503:physiopathology; D011877:Radionuclide Imaging; D051598:Whole Body Imaging
chemical_list: D007457:Iodine Radioisotopes