title: Structure-activity relationships in group 3 metal catalysts for asymmetric intramolecular alkene hydroamination. An investigation of ligands based on the axially chiral 1,1'-binaphthyl-2,2'-diamine motif.
abstract: From a series of N,N'-disubstituted-1,1'-binaphthyl-2,2'-diamines, several group 3 metal complexes were synthesized via an in situ procedure. These chiral complexes were subsequently applied to catalysis of intramolecular alkene hydroamination. Significant structure-activity relationships were observed, most notably a reversal of stereoselectivity for cyclopentyl versus diphenylmethyl substituents.
authors.affiliation: Department of Chemistry and Biochemistry, Montana State University, Bozeman, MT 59717, USA.
authors.forename: Helena M
authors.initials: HM
authors.lastname: Lovick
authors.forename: Duk K
authors.initials: DK
authors.lastname: An
authors.forename: Thomas S
authors.initials: TS
authors.lastname: Livinghouse
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D000586:Amination; D002384:Catalysis; D003959:Diamines / Q000737:chemistry*; D008024:Ligands; D008670:Metals / Q000737:chemistry*; D009281:Naphthalenes / Q000737:chemistry*; D011759:Pyrrolidines / Q000737:chemistry; D013237:Stereoisomerism; D013329:Structure-Activity Relationship; D015019:Yttrium / Q000737:chemistry
chemical_list: C500338:1,1'-binaphthyl-2,2'-diamine; D000475:Alkenes; D003959:Diamines; D008024:Ligands; D008670:Metals; D009281:Naphthalenes; D011759:Pyrrolidines; D015019:Yttrium; C032519:pyrrolidine