title: Deciding whether to go with the flow: evaluating the merits of flow reactors for synthesis.
abstract: The fine chemicals and pharmaceutical industries are transforming how their products are manufactured, where economically favorable, from traditional batchwise processes to continuous flow. This evolution is impacting synthetic chemistry on all scales-from the laboratory to full production. This Review discusses the relative merits of batch and micro flow reactors for performing synthetic chemistry in the laboratory.
authors.affiliation: Department of Chemical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Ave, 66-350, Cambridge, MA 02139, USA.
authors.forename: Ryan L
authors.initials: RL
authors.lastname: Hartman
authors.forename: Jonathan P
authors.initials: JP
authors.lastname: McMullen
authors.forename: Klavs F
authors.initials: KF
authors.lastname: Jensen
mesh_terms: D019149:Bioreactors; D060326:Chemistry Techniques, Synthetic / Q000295:instrumentation* / Q000379:methods*; D004345:Drug Industry; D007753:Laboratories; D046210:Microfluidic Analytical Techniques; D009930:Organic Chemicals / Q000138:chemical synthesis* / Q000737:chemistry; D004364:Pharmaceutical Preparations / Q000737:chemistry*
chemical_list: D009930:Organic Chemicals; D004364:Pharmaceutical Preparations