title: [Therapy of radiation enteritis--current challenges].
abstract: Radiation enteritis is one of the most feared complications after abdominal and pelvic radiation therapy. The incidence varies from 0.5 to 5%. It is not rare that the slowly progressing condition will be fatal. During a period of 13 years 24 patients were operated due to the complication of radiation enteritis. Despite different types of surgery repeated operation was required in 25% of cases and finally 4 patients died. Analyzing these cases predisposing factors and different therapeutic options of this condition are discussed. Treatment options of radiation induced enteritis are limited; however, targeted therapy significantly improves the outcome. Cooperation between oncologist, gastroenterologist and surgeon is required to establish adequate therapeutic plan.
authors.affiliation: Uzsoki Utcai Kórház Sebészet-Érsebészeti Osztály Budapest Uzsoki út 29. 1145 Tumorgenetika Biobank Klaszter Budapest. barazso@uzsoki.hu
authors.forename: Zsolt
authors.initials: Z
authors.lastname: Baranyai
authors.forename: Dániel
authors.initials: D
authors.lastname: Sinkó
authors.forename: Valéria
authors.initials: V
authors.lastname: Jósa
authors.forename: Attila
authors.initials: A
authors.lastname: Zaránd
authors.forename: Dániel
authors.initials: D
authors.lastname: Teknos
mesh_terms: D000328:Adult; D000368:Aged; D018450:Disease Progression; D004751:Enteritis / Q000209:etiology* / Q000401:mortality / Q000601:surgery*; D005260:Female; D006801:Humans; D006814:Hungary / Q000453:epidemiology; D033183:Interdisciplinary Communication; D008297:Male; D008875:Middle Aged; D011832:Radiation Injuries / Q000150:complications* / Q000209:etiology / Q000401:mortality / Q000601:surgery*; D012086:Reoperation; D016896:Treatment Outcome