title: Safety and efficacy of fibrin glue versus vicryl sutures in recurrent pterygium with amniotic membrane grafting.
abstract: OBJECTIVE
  The study aimed to compare surgical outcomes with likely toxic side effects when using pterygium excision and amniotic membrane grafting with fibrin glue versus Vicryl sutures.
  
  
  METHODS
  This is a prospective randomized study. Patients were classified into two groups: group 1 consisted of 20 patients with Vicryl-sutured grafts, and group 2 consisted of 20 patients with fibrin-glued grafts that were prepared from autologous blood. Results including surgery time, patient discomfort, complications and recurrence rates within 1, 6 and 12 months were analyzed.
  
  
  RESULTS
  The study demonstrated that there was a statistically significant decrease in surgery time in the fibrin glue group (the procedure took 17 min) relative to the sutured group (28 min; p < 0.05). Additionally, both postoperative pain and discomfort were noted significantly less often in the fibrin glue group. Complications were also decreased in the fibrin glue group.
  
  
  CONCLUSIONS
  The study revealed that the use of fibrin glue in pterygium surgery with amniotic membrane grafting was safer, less toxic and less time-consuming, and resulted in fewer complications than graft surgery with sutures.
authors.affiliation: Department of Ophthalmology, Faculty of Medicine, Zagazig University, Zagazig, Egypt. redaelmahdy2005@yahoo.com
authors.forename: Reda A
authors.initials: RA
authors.lastname: Mahdy
authors.forename: Mostafa M
authors.initials: MM
authors.lastname: Wagieh
mesh_terms: D000328:Adult; D000650:Amnion / Q000637:transplantation*; D001684:Biological Dressings; D005260:Female; D015718:Fibrin Tissue Adhesive / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011098:Polyglactin 910 / Q000009:adverse effects / Q000627:therapeutic use*; D011446:Prospective Studies; D011625:Pterygium / Q000628:therapy*; D012008:Recurrence; D013536:Suture Techniques; D013537:Sutures; D013997:Time Factors; D014014:Tissue Adhesives / Q000009:adverse effects / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D015718:Fibrin Tissue Adhesive; D014014:Tissue Adhesives; D011098:Polyglactin 910