title: Study on preparation of β-cyclodextrin encapsulation tea extract.
abstract: Microencapsulation of ethanol extract of tea was performed in this study. In order to microencapsulate, β-cyclodextrin was used as wall material. Ethanol extract of tea was used as the core material. Microcapsules in the solid form were obtained by drying the emulsions. RSM showed that optimal processing parameters were as followings: core material/wall material 1/4, β-cyclodextrin content 16%, stirring time 30 min and stirring temperature 200°C. Pharmacological activities of β-cyclodextrin encapsulation tea extract were determined. It was found that β-cyclodextrin encapsulation tea extract could enhance BMD, BMC and bone Ca, Zn and Cu contents. In addition, β-cyclodextrin encapsulation tea extract could still reduce blood Ca contents. These results indicated that β-cyclodextrin encapsulation tea extract was useful for improving bone quality in aged animals.
authors.affiliation: Hands and Feet Microsurgery, DaLian Municipal Central Hospital, DaLian City, PR China. lianghddr@yahoo.com.cn
authors.forename: Liang
authors.initials: L
authors.lastname: Haidong
authors.forename: Yu
authors.initials: Y
authors.lastname: Fang
authors.forename: Tong
authors.initials: T
authors.lastname: Zhihong
authors.forename: Ren
authors.initials: R
authors.lastname: Changle
mesh_terms: D000818:Animals; D015519:Bone Density / Q000187:drug effects; D002118:Calcium / Q000378:metabolism; D002851:Chromatography, High Pressure Liquid; D003300:Copper / Q000378:metabolism; D004339:Drug Compounding / Q000379:methods*; D000431:Ethanol; D016018:Least-Squares Analysis; D051379:Mice; D010936:Plant Extracts / Q000138:chemical synthesis* / Q000494:pharmacology; D013056:Spectrophotometry, Ultraviolet; D013662:Tea / Q000737:chemistry*; D015032:Zinc / Q000378:metabolism; D047392:beta-Cyclodextrins / Q000138:chemical synthesis* / Q000494:pharmacology
chemical_list: D010936:Plant Extracts; D013662:Tea; D047392:beta-Cyclodextrins; D000431:Ethanol; D003300:Copper; D015032:Zinc; C031215:betadex; D002118:Calcium