title: [Radical colpoparametrectomy after simple hysterectomy--operative treatment of patients with invasive cancer of the uterine corpus and cervix].
abstract: BACKGROUND
  Diagnosis of invasive cervical carcinoma or residual tumor disease in patients who had previously simple hysterectomy means that the initial surgery is incomplete according to the oncological standards. One of the options in such cases is a second stage surgery--radical colpoparametrectomy (RC).
  
  
  METHODS
  A retro- and prospective study during a period of Feb 1994-Jun 2010 enrolled a total of 28 patients that underwent RC after simple hysterectomy. Data were collected on demographics, tumor stage, histology, postoperative therapy, survival, complications.
  
  
  RESULTS
  Median age of patients was 54.7 years. Invasive cervical carcinoma was diagnosed in 20 of 28 patients. Residual tumor disease was found in 5/28 patients who had simple hysterectomy for endometrial cancer. Uterine sarcoma was diagnosed in 3 cases. Histology revealed absence of tumor in 10/28 patients, lymph nodes, vaginal, and/or parametrial metastases in 18/28. Postoperative radiation and/or chemotherapy was arranged in 19/28 cases. Median follow up was 56 months with an overall 5-year survival of 88%. 11/28 patients had postoperative complications.
  
  
  CONCLUSIONS
  RC is an alternative therapeutic approach for patients with invasive cancer of the uterine corpus and cervix who had simple hysterectomy.
authors.forename: B
authors.initials: B
authors.lastname: Slavchev
authors.forename: P
authors.initials: P
authors.lastname: Markov
authors.forename: Sv
authors.initials: S
authors.lastname: Slavov
mesh_terms: D002277:Carcinoma / Q000473:pathology* / Q000601:surgery*; D002584:Cervix Uteri / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D007044:Hysterectomy / Q000009:adverse effects*; D008875:Middle Aged; D009361:Neoplasm Invasiveness / Q000473:pathology; D011446:Prospective Studies; D012189:Retrospective Studies; D002583:Uterine Cervical Neoplasms / Q000473:pathology* / Q000601:surgery*; D014599:Uterus / Q000473:pathology / Q000601:surgery*