title: Current strategies for the prevention and management of central line-associated bloodstream infections.
abstract: Central venous catheters are an invaluable tool for diagnostic and therapeutic purposes in today's medicine, but their use can be complicated by bloodstream infections (BSIs). While evidence-based preventive measures are disseminated by infection control associations, the optimal management of established central line-associated BSIs has been summarized in infectious diseases guidelines. We prepared an overview of the state-of-the-art of prevention and management of central line-associated BSIs and included topics such as the role of antibiotic-coated catheters, the role of catheter removal in the management, and a review of currently used antibiotic compounds and the duration of treatment.
authors.affiliation: Division of Infectious Diseases, Washington University School of Medicine in St Louis, St Louis, MO, USA.
authors.forename: Zhuolin
authors.initials: Z
authors.lastname: Han
authors.forename: Stephen Y
authors.initials: SY
authors.lastname: Liang
authors.forename: Jonas
authors.initials: J
authors.lastname: Marschall