title: Celiac disease screening in patients with scleroderma.
abstract: Both celiac disease and scleroderma have autoimmune etiology and affect the bowel causing diarrhea. As an association of autoimmune disease in a single individual is not rare, it is important to know if a patient with scleroderma may also have celiac disease. To analyze this we studied 105 scleroderma patients and 97 volunteers for IgA-EmA by indirect immunofluorescence assay. We could not find a higher prevalence of this autoantibody in scleroderma patients. The authors conclude that there is no need to screen scleroderma patients with diarrhea for celiac disease unless there is a clear clinical indication for this.
authors.affiliation: Immunopathology Laboratory, Hospital de Clínicas, Curitiba, PR, Brazil.
authors.forename: Renato
authors.initials: R
authors.lastname: Nisihara
authors.forename: Shirley Rosa
authors.initials: SR
authors.lastname: Utiyama
authors.forename: Pedro Ming
authors.initials: PM
authors.lastname: Azevedo
authors.forename: Thelma Larocca
authors.initials: TL
authors.lastname: Skare
mesh_terms: D000328:Adult; D001323:Autoantibodies / Q000097:blood*; D016022:Case-Control Studies; D002446:Celiac Disease / Q000150:complications / Q000175:diagnosis*; D005260:Female; D019084:Fluorescent Antibody Technique, Indirect; D006801:Humans; D007070:Immunoglobulin A / Q000097:blood*; D008297:Male; D012595:Scleroderma, Systemic / Q000150:complications*; D011503:Transglutaminases / Q000097:blood*
chemical_list: D001323:Autoantibodies; D007070:Immunoglobulin A; D011503:Transglutaminases