title: Integration and visualization of host-pathogen data related to infectious diseases.
abstract: BACKGROUND
  Infectious disease research is generating an increasing amount of disparate data on pathogenic systems. There is a growing need for resources that effectively integrate, analyze, deliver and visualize these data, both to improve our understanding of infectious diseases and to facilitate the development of strategies for disease control and prevention.
  
  
  RESULTS
  We have developed Disease View, an online host-pathogen resource that enables infectious disease-centric access, analysis and visualization of host-pathogen interactions. In this resource, we associate infectious diseases with corresponding pathogens, provide information on pathogens, pathogen virulence genes and the genetic and chemical evidences for the human genes that are associated with the diseases. We also deliver the relationships between pathogens, genes and diseases in an interactive graph and provide the geolocation reports of associated diseases around the globe in real time. Unlike many other resources, we have applied an iterative, user-centered design process to the entire resource development, including data acquisition, analysis and visualization.
  
  
  METHODS
  Freely available at http://www.patricbrc.org; all major web browsers supported.
  
  
  BACKGROUND
  cmao@vbi.vt.edu
  
  
  BACKGROUND
  Supplementary data are available at Bioinformatics online.
authors.affiliation: Virginia Bioinformatics Institute, Virginia Tech, Blacksburg, VA 24061, USA.
authors.forename: Timothy
authors.initials: T
authors.lastname: Driscoll
authors.forename: Joseph L
authors.initials: JL
authors.lastname: Gabbard
authors.forename: Chunhong
authors.initials: C
authors.lastname: Mao
authors.forename: Oral
authors.initials: O
authors.lastname: Dalay
authors.forename: Maulik
authors.initials: M
authors.lastname: Shukla
authors.forename: Clark C
authors.initials: CC
authors.lastname: Freifeld
authors.forename: Anne Gatewood
authors.initials: AG
authors.lastname: Hoen
authors.forename: John S
authors.initials: JS
authors.lastname: Brownstein
authors.forename: Bruno W
authors.initials: BW
authors.lastname: Sobral
mesh_terms: D001419:Bacteria / Q000472:pathogenicity; D001424:Bacterial Infections / Q000382:microbiology; D003141:Communicable Diseases / Q000453:epidemiology / Q000235:genetics / Q000382:microbiology*; D019295:Computational Biology; D003196:Computer Graphics; D016208:Databases, Factual; D054884:Host-Pathogen Interactions; D006801:Humans; D012984:Software; D018511:Systems Integration; D014774:Virulence