title: [Strategy of the metabolic acidosis correction and indices of coagulation profile in patients with severe traumatic shock].
abstract: The strategy for correction of metabolic acidosis and coagulation profile disorders in severe traumatic shock was adduced. There was established, that severe traumatic shock is characterized by prominent metabolic acidosis, the bases deficiency reduction, the lactate content in arterial blood enhancement, as well as ionized calcium in the blood serum, significant enhancement of the partially activated thromboplastin time and protrombin time, what witnesses the prominent coagulation disorders presence on the metabolic acidosis background. The "Soda-buffer" (manufactured by "Yuriya Pharm", Ukraine) preparation application in a complex of infusion-transfusion therapy permits in early terms to correct effectively the metabolic acidosis and coagulopathy signs in the injured persons, suffering severe trauma. Effective correction of metabolic acidosis and disorders of coagulation profile permits to lower trustworthily the erythrocytic mass volume transfused as well as fresh-frozen plasm while the infusion-transfusion therapy conduction.
authors.forename: I P
authors.initials: IP
authors.lastname: Shlapak
authors.forename: L V
authors.initials: LV
authors.lastname: Zgrzheblovskaia
authors.forename: I R
authors.initials: IR
authors.lastname: Malysh
authors.forename: I A
authors.initials: IA
authors.lastname: Beshleĭ
mesh_terms: D018806:APACHE; D000138:Acidosis / Q000097:blood / Q000188:drug therapy* / Q000209:etiology; D000293:Adolescent; D000328:Adult; D001777:Blood Coagulation / Q000187:drug effects*; D001778:Blood Coagulation Disorders / Q000097:blood / Q000188:drug therapy* / Q000209:etiology; D002021:Buffers; D004359:Drug Therapy, Combination; D005440:Fluid Therapy; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008875:Middle Aged; D012774:Shock, Traumatic / Q000097:blood* / Q000150:complications / Q000378:metabolism*; D017693:Sodium Bicarbonate / Q000008:administration & dosage / Q000737:chemistry / Q000627:therapeutic use*; D015599:Trauma Severity Indices; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D002021:Buffers; D017693:Sodium Bicarbonate