title: Effect of the probiotic Enterococcus faecium SF68 on presence of diarrhea in cats and dogs housed in an animal shelter.
abstract: BACKGROUND
  Beneficial effects of probiotics have never been analyzed in an animal shelter.
  
  
  OBJECTIVE
  Dogs and cats housed in an animal shelter and administered a probiotic are less likely to have diarrhea of ≥2 days duration than untreated controls.
  
  
  METHODS
  Two hundred and seventeen cats and 182 dogs.
  
  
  METHODS
  Double blinded and placebo controlled. Shelter dogs and cats were housed in 2 separate rooms for each species. For 4 weeks, animals in 1 room for each species was fed Enterococcus faecium SF68 while animals in the other room were fed a placebo. After a 1-week washout period, the treatments by room were switched and the study continued an additional 4 weeks. A standardized fecal score system was applied to feces from each animal every day by a blinded individual. Feces of animals with and without diarrhea were evaluated for enteric parasites. Data were analyzed by a generalized linear mixed model using a binomial distribution with treatment being a fixed effect and the room being a random effect.
  
  
  RESULTS
  The percentage of cats with diarrhea ≥2 days was significantly lower (P = .0297) in the probiotic group (7.4%) when compared with the placebo group (20.7%). Statistical differences between groups of dogs were not detected but diarrhea was uncommon in both groups of dogs during the study.
  
  
  CONCLUSIONS
  Cats fed SF68 had fewer episodes of diarrhea of ≥2 days when compared with controls suggests the probiotic may have beneficial effects on the gastrointestinal tract.
authors.affiliation: Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO 80523-1678, USA. shawn.bybee@gmail.com
authors.forename: S N
authors.initials: SN
authors.lastname: Bybee
authors.forename: A V
authors.initials: AV
authors.lastname: Scorza
authors.forename: M R
authors.initials: MR
authors.lastname: Lappin
mesh_terms: D000818:Animals; D002371:Cat Diseases / Q000469:parasitology / Q000517:prevention & control*; D002415:Cats; D018592:Cross-Over Studies; D003967:Diarrhea / Q000469:parasitology / Q000517:prevention & control / Q000662:veterinary*; D004283:Dog Diseases / Q000469:parasitology / Q000517:prevention & control*; D004285:Dogs; D004311:Double-Blind Method; D016984:Enterococcus faecium; D005243:Feces / Q000469:parasitology; D005260:Female; D016014:Linear Models; D008297:Male; D015995:Prevalence; D019936:Probiotics / Q000008:administration & dosage*