title: Conducting polymer nanowires-based label-free biosensors.
abstract: Label-free sensing technologies have recently attracted a great deal of interest for sensitive, rapid and facile analysis for applications in health care, environmental monitoring, food safety and homeland security. One-dimensional (1-D) nanostructures such as nanowires, configured as field-effect transistors (FETs)/chemiresistors that change conductance upon binding of charged macromolecules to receptors linked to the device surfaces are extremely attractive for label-free biosensors. Herein, we review recent advances in label-free biosensors based on conducting polymer nanowires based FET/chemiresistor. Specifically, we address the fabrication, functionalization, assembly/alignment and sensing applications of FET/chemiresistor based on these nanomaterials. The advantages and disadvantages of various fabrication, functionalization, and assembling procedures of these nanosensors are reviewed and discussed.
authors.affiliation: Department of Chemical and Environmental Engineering, University of California, Riverside, CA 92521, United States. adani@engr.ucr.edu
authors.forename: Ashok
authors.initials: A
authors.lastname: Mulchandani
authors.forename: Nosang V
authors.initials: NV
authors.lastname: Myung
mesh_terms: D015374:Biosensing Techniques / Q000379:methods*; D006801:Humans; D046911:Macromolecular Substances; D049329:Nanostructures / Q000737:chemistry; D053770:Nanowires / Q000737:chemistry*; D011108:Polymers / Q000737:chemistry; D014173:Transistors, Electronic
chemical_list: D046911:Macromolecular Substances; D011108:Polymers