title: SEAL: a distributed short read mapping and duplicate removal tool.
abstract: CONCLUSIONS
  SEAL is a scalable tool for short read pair mapping and duplicate removal. It computes mappings that are consistent with those produced by BWA and removes duplicates according to the same criteria employed by Picard MarkDuplicates. On a 16-node Hadoop cluster, it is capable of processing about 13 GB per hour in map+rmdup mode, while reaching a throughput of 19 GB per hour in mapping-only mode.
  
  
  BACKGROUND
  SEAL is available online at http://biodoop-seal.sourceforge.net/.
authors.affiliation: CRS4, Polaris, Ed. 1, I-09010 Pula, Italy. luca.pireddu@crs4.it
authors.forename: Luca
authors.initials: L
authors.lastname: Pireddu
authors.forename: Simone
authors.initials: S
authors.lastname: Leo
authors.forename: Gianluigi
authors.initials: G
authors.lastname: Zanetti
mesh_terms: D000465:Algorithms; D019295:Computational Biology / Q000379:methods*; D016415:Sequence Alignment / Q000379:methods; D017422:Sequence Analysis, DNA / Q000379:methods*; D012984:Software