title: Aromatase inhibitors in men: effects and therapeutic options.
abstract: Aromatase inhibitors effectively delay epiphysial maturation in boys and improve testosterone levels in adult men Therefore, aromatase inhibitors may be used to increase adult height in boys with gonadotropin-independent precocious puberty, idiopathic short stature and constitutional delay of puberty. Long-term efficacy and safety of the use of aromatase inhibitors has not yet been established in males, however, and their routine use is therefore not yet recommended.
authors.affiliation: Department of Internal Medicine, Erasmus university Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands.
authors.forename: Willem
authors.initials: W
authors.lastname: de Ronde
authors.forename: Frank H
authors.initials: FH
authors.lastname: de Jong
mesh_terms: D000293:Adolescent; D047072:Aromatase Inhibitors / Q000009:adverse effects / Q000627:therapeutic use*; D001827:Body Height / Q000187:drug effects*; D001846:Bone Development / Q000187:drug effects; D001940:Breast / Q000187:drug effects; D002648:Child; D006130:Growth Disorders / Q000188:drug therapy*; D006801:Humans; D008297:Male; D009765:Obesity / Q000188:drug therapy; D011627:Puberty / Q000187:drug effects*; D011629:Puberty, Precocious / Q000188:drug therapy*; D013091:Spermatogenesis / Q000187:drug effects; D013739:Testosterone
chemical_list: D047072:Aromatase Inhibitors; D013739:Testosterone