title: Does stroke volume variation predict intraoperative blood loss in living right donor hepatectomy?
abstract: BACKGROUND
  Although stroke volume variation (SVV) is a valuable index of preload responsiveness, there is limited information about the association between low SVV and increased hepatectomy-related bleeding. We therefore evaluated whether SVV predicts blood loss during living donor hepatectomy.
  
  
  METHODS
  We evaluated 93 adult liver donors undergoing right hepatectomy for transplantation. Arterial blood pressure, heart rate, body temperature, central venous pressure, SVV, cardiac output, and systemic vascular resistance were measured. Logistic regression and receiver operating characteristic (ROC) curve analyses were performed to determine independent factors and optimal cutoff values of hemodynamic parameters for predicting intraoperative blood loss ≥ 700 mL.
  
  
  RESULTS
  Of these 93 donors, 36 (38.7%) had blood loss ≥ 700 mL. Univariate logistic regression analysis showed that factors associated with blood loss ≥ 700 mL included heart rate, SVV, cardiac output, and systemic vascular resistance. Multivariate logistic regression analysis revealed that only SVV was an independent predictor of blood loss ≥ 700 mL. ROC curve analysis showed that the optimal cutoff value for SVV predicting blood loss ≥ 700 mL was 6% (area under the curve = 0.64).
  
  
  CONCLUSIONS
  SVV is a significant independent predictor of blood loss ≥ 700 mL during donor hepatectomy, suggesting that low SVV may provide useful information on intraoperative bleeding in donors undergoing right hepatectomy.
authors.affiliation: Department of Anesthesiology and Pain Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. kyk@amc.seoul.kr
authors.forename: Y K
authors.initials: YK
authors.lastname: Kim
authors.forename: W J
authors.initials: WJ
authors.lastname: Shin
authors.forename: J G
authors.initials: JG
authors.lastname: Song
authors.forename: I G
authors.initials: IG
authors.lastname: Jun
authors.forename: G S
authors.initials: GS
authors.lastname: Hwang
mesh_terms: D000328:Adult; D016063:Blood Loss, Surgical; D001794:Blood Pressure; D001831:Body Temperature; D005260:Female; D006339:Heart Rate; D006801:Humans; D016031:Liver Transplantation; D019520:Living Donors; D008297:Male; D012372:ROC Curve; D013318:Stroke Volume