title: Synthesis of alanine-based colorimetric sensors and enantioselective recognition of aspartate and malate anions.
abstract: Two chiral colorimetric sensors (1,2) were synthesized and characterized by spectroscopic techniques and their enantioselective recognition of chiral dicarboxylic anions (D/L-aspartate and D/L-malate) was examined by UV-vis and (1)H NMR spectroscopy. Interaction of the receptors 1 and 2 with the enantiomers of aspartate or malate caused different color changes, and they act as optical chemosensors for the recognition of D-aspartate vs. L-aspartate and d-malate vs.l-malate. Receptor 1 exhibits high enantioselective binding for aspartate anions [K(A(D))/K(A(L)) = 12.15].
authors.affiliation: Department of Applied Chemistry, Providence University, 200 Chungchi Road, Sha-Lu, Taichung Hsien 433, Taiwan.
authors.forename: Wei-Chi
authors.initials: WC
authors.lastname: Lin
authors.forename: Yu-Ping
authors.initials: YP
authors.lastname: Tseng
authors.forename: Chi-Yung
authors.initials: CY
authors.lastname: Lin
authors.forename: Yao-Pin
authors.initials: YP
authors.lastname: Yen
mesh_terms: D000409:Alanine / Q000737:chemistry*; D000838:Anions; D001224:Aspartic Acid / Q000737:chemistry*; D002863:Chromogenic Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D003124:Colorimetry / Q000379:methods; D009682:Magnetic Resonance Spectroscopy; D008293:Malates / Q000737:chemistry*; D015394:Molecular Structure; D011789:Quantum Theory; D013237:Stereoisomerism
chemical_list: D000838:Anions; D002863:Chromogenic Compounds; D008293:Malates; D001224:Aspartic Acid; C030298:malic acid; D000409:Alanine