title: [Vitamin D and hypertension].
abstract: Low levels of vitamin D, defined as levels of 25-hydroxyvitamin D < 20-30 ng/ml, is a prevalent problem in the general population. Besides the classic relation with musculoskeletal disease, vitamin D has been also related to autoimmune diseases, cancer, metabolic diseases or cardiovascular diseases. High blood pressure, as the main cardiovascular risk factor, also has been related to vitamin D deficiency, constituting two prevalent worldwide health problems. Therefore, this article reviews the most important studies that combine both pathologies, the biological mechanism that relate them and the current evidence about the effect of vitamin D supplementation on hypertension.
authors.affiliation: Servicio de Nefrología, Hospital Costa del Sol, Marbella, Málaga, España. tanitak@hotmail.com
authors.forename: Cayetana
authors.initials: C
authors.lastname: Moyano Peregrín
authors.forename: Francisca
authors.initials: F
authors.lastname: López Rodríguez
authors.forename: Maria Del Mar
authors.initials: Mdel M
authors.lastname: Castilla Castellano
mesh_terms: D000818:Animals; D001327:Autoimmune Diseases / Q000453:epidemiology; D001711:Biotransformation; D002118:Calcium / Q000378:metabolism; D002318:Cardiovascular Diseases / Q000453:epidemiology; D015897:Comorbidity; D004032:Diet; D004198:Disease Susceptibility; D006801:Humans; D006973:Hypertension / Q000188:drug therapy / Q000453:epidemiology / Q000378:metabolism*; D007668:Kidney / Q000378:metabolism; D009026:Mortality; D009369:Neoplasms / Q000453:epidemiology; D010758:Phosphorus / Q000378:metabolism; D011446:Prospective Studies; D051381:Rats; D018167:Receptors, Calcitriol / Q000172:deficiency / Q000502:physiology; D013472:Sunlight; D014807:Vitamin D / Q000378:metabolism / Q000493:pharmacokinetics / Q000502:physiology* / Q000627:therapeutic use; D014808:Vitamin D Deficiency / Q000453:epidemiology / Q000503:physiopathology*
chemical_list: D018167:Receptors, Calcitriol; D014807:Vitamin D; D010758:Phosphorus; D002118:Calcium