title: Intramolecular Diels-Alder cycloaddition/rearrangement cascade of an amidofuran derivative for the synthesis of (±)-minfiensine.
abstract: An efficient synthesis of (±)-minfiensine has been accomplished employing an intramolecular Diels-Alder cycloaddition/rearrangement cascade of an amidofuran derivative. Thermal reorganization of the initially formed [4+2]-cycloadduct affords the critical tetrahydroiminoethanocarbazole skeleton of the alkaloid in high yield.
authors.affiliation: Department of Chemistry, Emory University, Atlanta, Georgia 30322, USA.
authors.forename: Gang
authors.initials: G
authors.lastname: Li
authors.forename: Albert
authors.initials: A
authors.lastname: Padwa
mesh_terms: D000586:Amination; D002227:Carbazoles / Q000138:chemical synthesis*; D003500:Cyclization; D005663:Furans / Q000737:chemistry*; D015394:Molecular Structure
chemical_list: D002227:Carbazoles; D005663:Furans; C504098:minfiensine; C039281:furan