title: [Infections related to central venous catheters in children affected from malignant diseases].
abstract: Central venous catheters (CVC) are an essential part of the treatment of children with haematological and oncological diseases. Unfortunately, CVC also represent a major risk factor of bloodstream infections. Catheter-related bloodstream infections (CRBSI) in children are often diagnosed based on blood cultures from the CVC only. Most CRBSI can be treated without catheter removal. On suspicion of CRBSI empirical antibiotic treatment with piperacillin-tazobactam, meropenem or ampicillin in combination with gentamicin is recommended. The systemic treatment can be combined with catheter-lock therapy.
authors.affiliation: Børneafdeling A4, Aarhus Universitetshospital, Skejby, 8200 Aarhus N, Denmark. Handrup@ki.au.dk
authors.forename: Mette Møller
authors.initials: MM
authors.lastname: Handrup
authors.forename: Jens Kjølseth
authors.initials: JK
authors.lastname: Møller
authors.forename: Henrik
authors.initials: H
authors.lastname: Schrøder
mesh_terms: D055499:Catheter-Related Infections / Q000175:diagnosis / Q000382:microbiology* / Q000517:prevention & control; D002405:Catheterization, Central Venous / Q000009:adverse effects* / Q000295:instrumentation; D002408:Catheters, Indwelling / Q000009:adverse effects; D002648:Child; D019091:Critical Pathways; D020878:Device Removal; D006402:Hematologic Diseases / Q000150:complications / Q000628:therapy; D006801:Humans; D009369:Neoplasms / Q000150:complications / Q000628:therapy