title: History of human papillomavirus, warts and cancer: what do we know today?
abstract: Human papillomavirus has been a cause of infection in humans for thousands of years. The history of papillomaviruses, knowledge of their causative role in benign and malignant disease, and their structural characteristics have led to the development of vaccines to prevent cervical and anogenital cancers. Many questions remain unanswered before HPV vaccines can be optimised; however, the concept of virtual eradication of cervical cancer is not impossible, and remains a realistic aspiration.
authors.affiliation: Department of Obstetrics and Gynaecology, University Hospital of South Manchester NHS Foundation Trust, UK. toli.onon@uhsm.nhs.uk
authors.forename: Toli S
authors.initials: TS
authors.lastname: Onon
mesh_terms: D052685:Alphapapillomavirus / Q000472:pathogenicity; D003218:Condylomata Acuminata / Q000453:epidemiology / Q000266:history / Q000517:prevention & control / Q000821:virology; D005260:Female; D049671:History, 18th Century; D049672:History, 19th Century; D049673:History, 20th Century; D049674:History, 21st Century; D049690:History, Ancient; D006801:Humans; D030361:Papillomavirus Infections / Q000453:epidemiology / Q000266:history* / Q000517:prevention & control; D053918:Papillomavirus Vaccines / Q000266:history; D002583:Uterine Cervical Neoplasms / Q000453:epidemiology / Q000266:history* / Q000517:prevention & control / Q000821:virology
chemical_list: D053918:Papillomavirus Vaccines