title: Rapid urinary output normalization method using specific gravity.
abstract: Spot urine samples are often taken for emergency radiobioassay to provide a quick dose assessment for contaminated individuals. The subsequent dosimetric analysis requires a urinary output normalization method to adjust spot sampling to daily urine excretion. A rapid specific gravity method that was developed for 24-h urinary output correction is described. Spot urine samples were collected from volunteers of different race, gender, and age to validate the normalization method. Results show that a specific gravity test is a fast, easy and robust method to correct the urine excretion in the event of a radiation emergency.
authors.affiliation: Chalk River Laboratories, Atomic Energy of Canada Limited, Chalk River, Ontario K0J 1J0, Canada. daix@aecl.ca
authors.forename: Xiongxin
authors.initials: X
authors.lastname: Dai
authors.forename: Kaitlyn
authors.initials: K
authors.lastname: Kutschke
authors.forename: Nicholas
authors.initials: N
authors.lastname: Priest
mesh_terms: D000328:Adult; D004630:Emergencies; D004635:Emergency Medicine / Q000379:methods* / Q000592:standards; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011834:Radiation Monitoring / Q000379:methods* / Q000592:standards; D011868:Radioisotopes / Q000032:analysis* / Q000652:urine; D015203:Reproducibility of Results; D013046:Specific Gravity; D013997:Time Factors
chemical_list: D011868:Radioisotopes