title: [Renal amyloidosis: uncommon complication of sickle cell disease].
abstract: Type AA amyloidosis is a rare complication of sickle cell anemia. The purpose of this report is to describe the case of a 30-year-old man with heterozygous sickle cell disease who was referred to our unit with nephritic syndrome and microscopic hematuria. Light microscopy on a renal biopsy specimen demonstrated AA amyloidosis. After elimination of other causes, it was concluded that amyloidosis was the result of recurrent acute inflammation secondary to sickle cell disease. To our knowledge, this is the fifth that renal amyloidosis as a complication of sickle cell disease has been described in the literature.
authors.affiliation: Service de Néphrologie-Dialyse et Transplantation Rénale, CHU Ibn Sina, Rabat, Maroc. bahaahadjsadek@yahoo.fr
authors.forename: B
authors.initials: B
authors.lastname: Hadj Sadek
authors.forename: A
authors.initials: A
authors.lastname: Radoui
authors.forename: Z
authors.initials: Z
authors.lastname: Al Hamany
authors.forename: L
authors.initials: L
authors.lastname: Benamar
authors.forename: R
authors.initials: R
authors.lastname: Bayahia
authors.forename: N
authors.initials: N
authors.lastname: Ouzeddoun
mesh_terms: D000328:Adult; D000686:Amyloidosis / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D000755:Anemia, Sickle Cell / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000627:therapeutic use; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D001706:Biopsy; D004359:Drug Therapy, Combination; D006801:Humans; D007674:Kidney Diseases / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D008297:Male; D017257:Ramipril / Q000627:therapeutic use; D035583:Rare Diseases; D016896:Treatment Outcome
chemical_list: D000806:Angiotensin-Converting Enzyme Inhibitors; D000894:Anti-Inflammatory Agents, Non-Steroidal; D017257:Ramipril