title: Epidural spinal tumor and periaortitis as rare complications of Wegener's granulomatosis.
abstract: This case report describes findings in a 61-year-old woman who manifested scleritis, small pulmonary nodules, otitis media, periaortitis, and progressive epidural spinal tumor, associated with elevated serum myeloperoxidase anti-neutrophil cytoplasmic antibody (MPO-ANCA) levels. She was clinically diagnosed with Wegener's granulomatosis, although vasculitis was not diagnosed due to the lack of typical histological findings. We discuss the differential diagnosis in this patient, and the association of MPO-ANCA with periaortitis or epidural spinal tumor.
authors.affiliation: Department of Clinical Pathology and Immunology, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-Cho, Chuo-ku, Kobe, Hyogo 650-0017, Japan. kobe470@med.kobe-u.ac.jp
authors.forename: Shimpei
authors.initials: S
authors.lastname: Kasagi
authors.forename: Jun
authors.initials: J
authors.lastname: Saegusa
authors.forename: Goh
authors.initials: G
authors.lastname: Tsuji
authors.forename: Sho
authors.initials: S
authors.lastname: Sendo
authors.forename: Natsuko
authors.initials: N
authors.lastname: Miura
authors.forename: Hiroki
authors.initials: H
authors.lastname: Hayashi
authors.forename: Takeshi
authors.initials: T
authors.lastname: Sugimoto
authors.forename: Seiji
authors.initials: S
authors.lastname: Kawano
authors.forename: Kotaro
authors.initials: K
authors.lastname: Nishida
authors.forename: Kenichiro
authors.initials: K
authors.lastname: Kakutani
authors.forename: Akio
authors.initials: A
authors.lastname: Morinobu
authors.forename: Shunichi
authors.initials: S
authors.lastname: Kumagai
mesh_terms: D015174:Epidural Neoplasms / Q000150:complications* / Q000473:pathology; D005260:Female; D014890:Granulomatosis with Polyangiitis / Q000150:complications* / Q000473:pathology; D006801:Humans; D007249:Inflammation / Q000473:pathology; D008875:Middle Aged; D012185:Retroperitoneal Fibrosis / Q000150:complications* / Q000473:pathology; D013904:Thoracic Vertebrae