title: Anti-angiogenic treatment (sunitinib) for disseminated malignant haemangiopericytoma: a case study and review of the literature.
abstract: BACKGROUND
  A meningeal haemangiopericytoma (HP) is a mesenchymal tumour that makes up less than 1% of all CNS tumours. HPs arise from pericytes and present high rates of recurrence and distant metastasis. The primary treatment option is surgery. When the disease is disseminated, chemotherapy produces a weak and short-lived response; therefore, new drugs are needed.
  
  
  METHODS
  We describe the case of a 65-year-old woman with a 13-year history of recurrent HP. After local treatment with radiotherapy, she developed metastases that required systemic treatment, and treatment with sunitinib, an oral inhibitor of the vascular endothelial growth factor receptor and the platelet-derived growth factor receptor, was initiated. As a result, radiological stabilisation of the systemic disease was maintained for over 12 months.
  
  
  CONCLUSIONS
  Anti-angiogenic agents can be useful for treating disseminated HP, but further studies are needed to confirm their possible role in controlling metastatic disease.
authors.affiliation: Division of Medical Oncology, Hospital Costa del Sol, Marbella, Spain.
authors.forename: M
authors.initials: M
authors.lastname: Delgado
authors.forename: E
authors.initials: E
authors.lastname: Pérez-Ruiz
authors.forename: J
authors.initials: J
authors.lastname: Alcalde
authors.forename: D
authors.initials: D
authors.lastname: Pérez
authors.forename: R
authors.initials: R
authors.lastname: Villatoro
authors.forename: A
authors.initials: A
authors.lastname: Rueda