title: Risk-taking and alcohol use disorders symptomatology in a sample of problem drinkers.
abstract: The relationship between risk-taking behavior and alcohol use disorder (AUD) symptoms is poorly understood. This study employed a modified version of a behavioral measure of risk-taking, the Balloon Analogue Risk Task (BART), to examine its relationship to alcohol use and related symptoms in a community sample of individuals with or at risk for AUD. A total of 158 (71.9% male) participants completed a testing battery that included the BART, a structured diagnostic interview for AUD, and measures of alcohol use and related problems. Estimates of IQ and working memory were assessed as covariates. Results indicated that the relationship between risk-taking propensity, as assessed by the BART, and alcohol problems was significant and negative. Individuals with higher symptom count made fewer pumps per trial on the BART, indicating less risk-taking. It is important to note that this relationship was attenuated when controlling for estimated IQ and working memory span. Further examination demonstrated that IQ and age mediated the relationship between risk-taking propensity and symptom count. The main negative relationship observed between risk-taking on the BART and alcohol use and AUD symptomatology in this sample stands in contrast to the positive relationships observed in adolescent and nonclinical samples. Together, these findings highlight the need to consider development and the course of addiction to fully elucidate the effects of risky-decision making on AUD liability. Furthermore, our results demonstrate the importance of inclusion of neurocognitive covariates (IQ), as well as demographic variables (age) when using this task.
authors.affiliation: Interdepartmental Neuroscience Program, Brain Research Institute, University of California, Los Angeles 90095-1563, USA.
authors.forename: James R
authors.initials: JR
authors.lastname: Ashenhurst
authors.forename: J David
authors.initials: JD
authors.lastname: Jentsch
authors.forename: Lara A
authors.initials: LA
authors.lastname: Ray
mesh_terms: D000328:Adult; D000428:Alcohol Drinking / Q000453:epidemiology / Q000523:psychology*; D019973:Alcohol-Related Disorders / Q000175:diagnosis / Q000453:epidemiology / Q000523:psychology*; D000437:Alcoholism / Q000175:diagnosis / Q000453:epidemiology / Q000523:psychology*; D002492:Central Nervous System Depressants / Q000009:adverse effects / Q000097:blood / Q000494:pharmacology*; D000431:Ethanol / Q000009:adverse effects / Q000097:blood / Q000494:pharmacology*; D005260:Female; D006801:Humans; D007361:Intelligence Tests; D007406:Interview, Psychological; D007407:Interviews as Topic; D008297:Male; D008570:Memory, Short-Term / Q000187:drug effects; D008875:Middle Aged; D011569:Psychiatric Status Rating Scales; D012309:Risk-Taking; D019966:Substance-Related Disorders / Q000175:diagnosis / Q000453:epidemiology / Q000523:psychology*
chemical_list: D002492:Central Nervous System Depressants; D000431:Ethanol