title: Correction of high myopia with a phakic intraocular lens: interim analysis of clinical and patient-reported outcomes.
abstract: OBJECTIVE
  To assess uncorrected distance visual acuity (UDVA) and patient-reported outcome changes after bilateral anterior chamber angle-fixated phakic intraocular lens (pIOL) implantation for high myopia.
  
  
  METHODS
  Multiple North American surgical centers.
  
  
  METHODS
  Nonrandomized multicenter clinical trials.
  
  
  METHODS
  This was a pooled interim analysis of 2 open-label single-arm studies of high myopia patients with bilateral anterior chamber angle-fixated pIOLs. Assessments compared baseline with 6-month, 1-year, and 2-year measurements. Outcomes included binocular UDVA, binocular corrected distance visual acuity (CDVA), satisfaction with vision, spectacle independence, and Refractive Status and Vision Profile (RSVP) questionnaire results.
  
  
  RESULTS
  One hundred thirty-eight patients (mean age 37 years, 67% women) completed all 4 assessments. The UDVA at 6 months, 1 year, and 2 years postoperatively was statistically better than the baseline CDVA (0.12 logMAR, 0.11 logMAR, 0.12 logMAR, respectively, versus 0.06 logMAR) (P<.005). The increase in preoperative to postoperative satisfaction with uncorrected vision was significant (P<.0001). Distance vision spectacle independence improved from 0% preoperatively to 94% postoperatively (P<.0001). Patients reported significant improvements in the RSVP overall score (P<.0001) and the following 7 subscales: concern with vision (P<.0001), driving (P<.001), problems with glare (P<.05), optical problems (P ≤.001), physical/social functioning (P<.0001), problems with corrective lenses (P<.005), and ocular symptoms (P<.0001).
  
  
  CONCLUSIONS
  After pIOL implantation, the UDVA was better than the preoperative CDVA and most patients required no distance vision correction, had improved satisfaction with uncorrected vision, and had improved vision-related quality of life.
authors.affiliation: Associated Eye Care, Stillwater, Minnesota, USA.
authors.forename: Stephen S
authors.initials: SS
authors.lastname: Lane
authors.forename: Curtis
authors.initials: C
authors.lastname: Waycaster
mesh_terms: D000328:Adult; D000867:Anterior Chamber / Q000601:surgery; D001334:Automobile Driving; D003261:Contact Lenses / Q000706:statistics & numerical data; D005139:Eyeglasses / Q000706:statistics & numerical data; D005260:Female; D019466:Glare; D006801:Humans; D019654:Lens Implantation, Intraocular / Q000379:methods*; D008297:Male; D008875:Middle Aged; D047728:Myopia, Degenerative / Q000503:physiopathology / Q000601:surgery*; D017060:Patient Satisfaction; D054120:Phakic Intraocular Lenses; D011788:Quality of Life; D011795:Surveys and Questionnaires; D016896:Treatment Outcome; D015348:Vision, Binocular / Q000502:physiology; D014792:Visual Acuity / Q000502:physiology; D055815:Young Adult