title: Complete atrioventricular block in adult Sjögren's syndrome with anti-Ro autoantibody.
abstract: Anti-Ro autoantibody is associated with Sjögren's syndrome (SS), systemic lupus erythematosus (SLE), and neonatal lupus syndrome (i.e., congenital complete heart block in newborns). Generally, the adult atrioventricular (AV) node is believed to be relatively resistant to the scarring effects of anti-Ro/anti-La autoantibodies. However, there have been some reports of adult complete AV block in SS and SLE patients. Here, we report a case of complete heart block in primary SS with anti-Ro autoantibodies, with no other risk factor for the development of heart block, and review their etiological association.
authors.affiliation: Department of Internal Medicine, Catholic University of Daegu School of Medicine, Arthritis and Autoimmunity Research Center, Daegu, Korea.
authors.forename: Myung Jun
authors.initials: MJ
authors.lastname: Sung
authors.forename: Sung-Hoon
authors.initials: SH
authors.lastname: Park
authors.forename: Seong-Kyu
authors.initials: SK
authors.lastname: Kim
authors.forename: Young-Soo
authors.initials: YS
authors.lastname: Lee
authors.forename: Chul-Yeon
authors.initials: CY
authors.lastname: Park
authors.forename: Jung-Yoon
authors.initials: JY
authors.lastname: Choe
mesh_terms: D000974:Antibodies, Antinuclear / Q000097:blood*; D054537:Atrioventricular Block / Q000175:diagnosis / Q000276:immunology* / Q000628:therapy; D002304:Cardiac Pacing, Artificial; D004562:Electrocardiography; D015716:Electrocardiography, Ambulatory; D005080:Exercise Test; D005260:Female; D006801:Humans; D008875:Middle Aged; D011237:Predictive Value of Tests; D012307:Risk Factors; D012859:Sjogren's Syndrome / Q000150:complications / Q000276:immunology*; D016896:Treatment Outcome
chemical_list: D000974:Antibodies, Antinuclear; C035356:SS-A antibodies