title: Diffuse intestinal angiomatosis as a possible paraneoplastic manifestation of small cell lung cancer: a case of small bowel angiomatosis.
abstract: Vascular malformations are rare, incompletely understood and heterogeneous in presentation and clinical course. They are known to be associated with a number of benign syndromes, commonly presenting in childhood. Angiomatosis is a form of vascular malformation, hardly documented in the English literature, and has only rarely been described in the small bowel. We present a case of a middle-aged female who developed small bowel obstruction secondary to diffuse small bowel angiomatosis and subsequently developed aggressive multifocal small cell lung cancer 2 months later. Her condition rapidly deteriorated with multiple metastases and she passed away 4 months later secondary to brain metastases and diffuse disease. Small cell lung cancer is well known for its association with paraneoplastic syndromes and has been reported to cause a rise in vascular endothelial growth factor. We postulate that in this case angiomatosis presented as a paraneoplastic syndrome associated with small cell lung cancer.
authors.affiliation: University Hospital Birmingham, Department of Gastroenterology, Queen Elizabeth Hospital, Edgbaston, Birmingham B156HT, UK.
authors.forename: Adam
authors.initials: A
authors.lastname: Low
authors.forename: Ella
authors.initials: E
authors.lastname: Mozdiak
authors.forename: Christopher
authors.initials: C
authors.lastname: Keh
authors.forename: Colm
authors.initials: C
authors.lastname: Forde
authors.forename: Rahul
authors.initials: R
authors.lastname: Hejmadi
authors.forename: Jason
authors.initials: J
authors.lastname: Goh