title: [Culture-negative bacterial meningitis diagnosed with polymerase chain reaction].
abstract: Aetiological diagnosis of patients with bacterial meningitis and possible secondary complications is crucial for the implementation of optimal treatment. Molecular biological methods such as polymerase chain reaction (PCR) can be used. We here present a clinical case in which the diagnosis of pneumococcal meningitis with a subsequent complication in the form of a secondary cerebral abscess was primarily made by real-time PCR after treatment had been initiated.
authors.affiliation: Afdeling for Mikrobiologisk Overvågning og Forskning, Statens Serum Institut, 2300 København S, Denmark. HIG@ssi.dk
authors.forename: Helene
authors.initials: H
authors.lastname: Ingels
authors.forename: Zitta
authors.initials: Z
authors.lastname: Harboe
authors.forename: Dorthe
authors.initials: D
authors.lastname: Andersen
authors.forename: Jens Erik Klint
authors.initials: JE
authors.lastname: Nielsen
authors.forename: Lise
authors.initials: L
authors.lastname: Jensen
mesh_terms: D001922:Brain Abscess / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000382:microbiology*; D005260:Female; D006801:Humans; D007223:Infant; D008586:Meningitis, Pneumococcal / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D016133:Polymerase Chain Reaction; D011859:Radiography; D013296:Streptococcus pneumoniae / Q000145:classification / Q000235:genetics