title: Clinical effectiveness of a desensitizing system on dentin hypersensitivity in periodontitis patients.
abstract: OBJECTIVE
  To evaluate the efficacy of the DenShield desensitizing system, based on calcium sodium phosphosilicate, in the hypersensitivity reduction for a 6-month period in periodontitis patients previously subjected to periodontal treatment and to compare the combination of the in-office paste and at-home dentifrice use to the at-home dentifrice use alone.
  
  
  METHODS
  A total of 248 teeth (eight teeth in each subject) in 31 periodontitis patients (mean age 48 +/- 8 years) previously subjected to periodontal treatment were studied. 193 (77.8%) teeth had been treated with phase I periodontal treatment alone (non-surgical treatment) and 55 (22.2%) had been additionally subjected to periodontal surgery. Periodontal clinical parameters were recorded for each subject. Hypersensitivity was assessed by tactile and air-blast stimuli. The hypersensitive teeth of each of two quadrants in each subject were randomly assigned with split-mouth design to in-office application of DenShield Starter paste (four teeth) or placebo (distilled water) (four teeth). After the in-office application each patient used the DenShield dentifrices (Builder and Saver) for 6 months. The final evaluation was at 6 months.
  
  
  RESULTS
  The prevalence and the degree of baseline hypersensitivity was significantly higher for the surgically than the non-surgically-treated teeth (83.6% versus 68.4%) and it was greater in teeth with attachment loss. The dentin hypersensitivity observed after periodontal treatment was significantly reduced in periodontitis patients who used the DenShield system for 6 months. There was no difference in hypersensitivity reduction between the additional in-office application of the DenShield and the at-home use of the DenShield dentifrices alone.
authors.affiliation: Department of Periodontology, School of Dentistry, University of Athens, Greece.
authors.forename: Aikaterini
authors.initials: A
authors.lastname: Patsouri
authors.forename: Afroditi
authors.initials: A
authors.lastname: Mavrogiannea
authors.forename: Eudoxie
authors.initials: E
authors.lastname: Pepelassi
authors.forename: Marianna
authors.initials: M
authors.lastname: Gaintantzopoulou
authors.forename: Afrodite
authors.initials: A
authors.lastname: Kakaboura
mesh_terms: D000328:Adult; D000368:Aged; D000704:Analysis of Variance; D016009:Chi-Square Distribution; D012534:Dental Scaling / Q000009:adverse effects; D003802:Dentifrices / Q000627:therapeutic use*; D057133:Dentin Desensitizing Agents / Q000737:chemistry / Q000627:therapeutic use*; D003807:Dentin Sensitivity / Q000188:drug therapy* / Q000209:etiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010518:Periodontitis / Q000601:surgery / Q000628:therapy*; D017640:Silicates / Q000627:therapeutic use; D018709:Statistics, Nonparametric
chemical_list: D003802:Dentifrices; D057133:Dentin Desensitizing Agents; D017640:Silicates