title: Description of primary multidrug-resistant tuberculous meningitis in an Italian child.
abstract: Tuberculous meningitis is the most severe form of tuberculosis and causes substantial morbidity and mortality in adults and children. The prevalence of multidrug-resistant (rifampin-isoniazid) strains requires the use of more toxic second-line drugs. We report a case of tuberculous meningitis in a 3-year-old Italian child.
authors.affiliation: Department of Microbiology and Virology, Azienda Ospedaliera SS Annunziata, Cosenza, Italy. m.v.mauro@virgilio.it
authors.forename: Maria Vittoria
authors.initials: MV
authors.lastname: Mauro
authors.forename: Paolina
authors.initials: P
authors.lastname: Cavalcanti
authors.forename: Raffaella
authors.initials: R
authors.lastname: Ledonne
authors.forename: Cristina
authors.initials: C
authors.lastname: Giraldi
authors.forename: Domenico
authors.initials: D
authors.lastname: Sperlì
mesh_terms: D000995:Antitubercular Agents / Q000494:pharmacology* / Q000627:therapeutic use; D002675:Child, Preschool; D024901:Drug Resistance, Multiple, Bacterial; D006801:Humans; D007538:Isoniazid / Q000494:pharmacology / Q000627:therapeutic use; D008297:Male; D009169:Mycobacterium tuberculosis / Q000235:genetics* / Q000302:isolation & purification; D012293:Rifampin / Q000494:pharmacology / Q000627:therapeutic use; D014390:Tuberculosis, Meningeal / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D018088:Tuberculosis, Multidrug-Resistant / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*
chemical_list: D000995:Antitubercular Agents; D007538:Isoniazid; D012293:Rifampin