title: [Morphological, clinical, diagnostic features and the treatment of patients with giant brain aneurisms].
abstract: Retrospective analysis of treatment outcomes of 89 patients with GIAs, treated in Sklifosovsky Emergency Care Institute from 01.01.1992 till 30.11.2010, was performed. 67 patients were operated on, among them open surgery was conducted for 49 patients, endovascular embolisation - 18 patients. Severity of patients' condition was assessed according to Hunt - Hess (H-H) scale, level of consciousness - Glasgow Coma Scale (GCS), treatment outcomes - Glasgow Outcomes Scale (GOS). Hemorrhage due to GIA rupture was seen at у 64 (72,0%) patients, mass lesion signs - at 18 (20,2%), embolic events - at 3 (3,4%) and GIA without any symptoms - at 4 (4,4%) patients. Good and excellent outcomes were at 79,1% operated patients, total lethality among operated patients was 13,4%. Lethality among non-operated patients was 47,4%. Conservative treatment of patients with GIAs has low perspectives. Open and endovascular operative interventions are the high-risk surgery but they allow decreasing the lethality and morbidity rate among these patients compared with conservative treatment.
authors.forename: V V
authors.initials: VV
authors.lastname: Krylov
authors.forename: A B
authors.initials: AB
authors.lastname: Klimov
authors.forename: N A
authors.initials: NA
authors.lastname: Polunina
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D002532:Intracranial Aneurysm / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery*; D018810:Magnetic Resonance Angiography; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D055815:Young Adult