title: [Clinical and diagnostic characteristics of the fatty acid spectrum of lipids in patients with generalized periodontitis].
abstract: A comparative analysis of complex survey of 67 patients with generalized periodontitis was carried out. In comparing different biological diagnostic media: in the peripheral blood (plasma and red blood cells), in the leachate content of periodontal pockets (PP) and a secret glandula Parotis, determined unidirectional imbalance of fatty acid spectrum (FA) due to excessive accumulation of saturated (LCD, NLC) and reduction in an amount of unsaturated (UFA) and polyunsaturated (PUFA) was defined, regardless of the disease course. Differential diagnostic and prognostic test in complex study of LCD spectrum is an excess oxidation of arachidonic acid (AA) in PP and plasma levels on the background of the identified imbalance, with significant reduction in accumulation of AK by 25% in erythrocyte membranes and the filtrate PC, which characterizes the change in plasticity and permeability of cell membranes, which affects their functional activity.
authors.forename: I E
authors.initials: IE
authors.lastname: Sergeeva
authors.forename: T S
authors.initials: TS
authors.lastname: Briuzgina
mesh_terms: D000328:Adult; D012634:Bodily Secretions / Q000378:metabolism; D016022:Case-Control Studies; D002849:Chromatography, Gas; D004912:Erythrocytes / Q000378:metabolism; D005227:Fatty Acids / Q000097:blood*; D006801:Humans; D050356:Lipid Metabolism; D008875:Middle Aged; D010084:Oxidation-Reduction; D010306:Parotid Gland / Q000378:metabolism; D010514:Periodontal Pocket / Q000097:blood / Q000378:metabolism; D010518:Periodontitis / Q000097:blood / Q000378:metabolism*; D055815:Young Adult
chemical_list: D005227:Fatty Acids