title: Acinic cell carcinoma of the parotid gland with skull base invasion: case study, managed by exclusive external 3D radiation therapy.
abstract: OBJECTIVE
  To review treatment options in a rare type of parotid tumor, in a clinical case study.
  
  
  METHODS
  A 62-year-old woman presenting with recurrence of acinic cell carcinoma of the parotid gland with invasion of the skull base was treated by external 3D conformational radiation, having refused large-scale exeresis. Sixty-six Gy (70Gy equivalent) were delivered in 2007. Clinical and paraclinical follow-up found regular tumor volume regression over a 2.5-year period without side-effects of radiation.
  
  
  CONCLUSIONS
  There are no specific data on the efficacy of external radiation therapy in acinic cell carcinoma; reports on exclusive radiation treatment of salivary gland cancer include different histological types. Exclusive radiation treatment should be at least 66-70Gy, preferably by neutron- or hadrontherapy.
  
  
  CONCLUSIONS
  Management of acinic cell carcinoma of the parotid is surgical with possible secondary radiation therapy; exclusive external radiation therapy is, however, an option in case of contra-indication for surgery or patient refusal.
authors.affiliation: Centre Léon-Bérard, 28 rue Laennec, Lyon, France. guillaume.buiret@laposte.net
authors.forename: G
authors.initials: G
authors.lastname: Buiret
authors.forename: P
authors.initials: P
authors.lastname: Céruse
authors.forename: A
authors.initials: A
authors.lastname: Ramade
authors.forename: C
authors.initials: C
authors.lastname: Carrie
authors.forename: P
authors.initials: P
authors.lastname: Pommier
mesh_terms: D018267:Carcinoma, Acinar Cell / Q000473:pathology / Q000532:radiotherapy*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D010307:Parotid Neoplasms / Q000473:pathology / Q000532:radiotherapy*; D020266:Radiotherapy, Conformal; D019292:Skull Base Neoplasms / Q000473:pathology / Q000532:radiotherapy*