title: Fatigue and aging with a disability.
abstract: OBJECTIVE
  To compare self-reported fatigue in 4 disability populations with age-matched, U.S. population norms. We assessed fatigue and age in a sample of individuals with spinal cord injury (SCI), postpolio syndrome (PPS), multiple sclerosis (MS), and muscular dystrophy (MD).
  
  
  METHODS
  This study used survey responses and published age cohort means for fatigue to test the hypothesis that fatigue would be higher in each of 4 clinical samples than the U.S. population norm. We also hypothesized that, for clinical samples, the mean fatigue reported within age cohorts would be higher than the general U.S. population norms for those age ranges derived in the Patient-Reported Outcomes Measurement Information System (PROMIS).
  
  
  METHODS
  Survey responses were collected from participants in the Washington state area.
  
  
  METHODS
  Participants (N=1836) were persons with MD (n=337), MS (n=580), Post-polio (n=441), and SCI (n=478).
  
  
  METHODS
  Not applicable.
  
  
  METHODS
  PROMIS Depression Short Form.
  
  
  RESULTS
  Individuals with disabilities reported higher levels of fatigue than the normative PROMIS population. In the normative population, self-reported fatigue was substantially lower in age cohorts from middle age to retirement age. However, individuals with disabilities did not demonstrate this age cohort effect.
  
  
  CONCLUSIONS
  Individuals with disabilities are not only at greater risk to experience fatigue, but this risk, relative to normative values, increases with age. More research is needed to determine the specific negative impact of fatigue symptoms on functioning in individuals with disabilities as they age.
authors.affiliation: Department of Rehabilitation Medicine, University of Washington School of Medicine, Seattle, WA, USA. karonc2@u.washington.edu
authors.forename: Karon F
authors.initials: KF
authors.lastname: Cook
authors.forename: Ivan R
authors.initials: IR
authors.lastname: Molton
authors.forename: Mark P
authors.initials: MP
authors.lastname: Jensen
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000375:Aging; D005221:Fatigue / Q000209:etiology*; D005260:Female; D006306:Health Surveys; D006801:Humans; D008297:Male; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000150:complications*; D009136:Muscular Dystrophies / Q000150:complications*; D016262:Postpoliomyelitis Syndrome / Q000150:complications*; D057566:Self Report; D013119:Spinal Cord Injuries / Q000150:complications*; D014861:Washington; D055815:Young Adult