title: Synthesis of d-labeled and unlabeled benzoyloxysuccinimides and application to quantitative analysis of peptides and a protein by isotope differential mass spectrometry.
abstract: Benzoyloxysuccinimide and its d(5)-labeled version, which react with amino groups in the N-termini and lysine side chains in proteins, were synthesized and applied to quantitative analysis of peptides and a commercially available protein in combination with a MALDI mass spectrometer.
authors.affiliation: Department of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX 79409-1061, USA.
authors.forename: Masoud
authors.initials: M
authors.lastname: Zabet-Moghaddam
authors.forename: Aarif L
authors.initials: AL
authors.lastname: Shaikh
authors.forename: Lauren B
authors.initials: LB
authors.lastname: Jones
authors.forename: Satomi
authors.initials: S
authors.lastname: Niwayama
mesh_terms: D000324:Adrenocorticotropic Hormone / Q000032:analysis; D000809:Angiotensins / Q000032:analysis; D006801:Humans; D007553:Isotope Labeling; D008239:Lysine / Q000737:chemistry; D010455:Peptides / Q000032:analysis*; D011506:Proteins / Q000032:analysis*; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / Q000379:methods*; D013388:Succinimides / Q000138:chemical synthesis / Q000737:chemistry*
chemical_list: D000809:Angiotensins; D010455:Peptides; D011506:Proteins; D013388:Succinimides; C516880:angiotensin A; D000324:Adrenocorticotropic Hormone; D008239:Lysine