title: [Study of measles history, vaccination, antibody status, and vaccination effectiveress for school teachers].
abstract: To determine an efficient measles vaccination program for school teachers, we studied knowledge about measles history, immunization, and immunity status among 269 school teachers in Ichihara City in 2009. We found that (1) many are uncertain about disease and immunization history, with neither history related to the immunity status of neutralizing antibody titer (NT), (2) particle agglutination (PA) and enzyme immunoassay (EIA) testing have replaced NT in commercial laboratories, but persons having antibodies fewer than 8-fold of the NT titer as a sensitivity desigration for measles, and 11 false-positive immunity results are indicated in PA testing (cutoff: 256-fold) and 140 false-positive sensitivity results in EIA testing (cutoff: 16.0 EIA), and (3) sensitivity cases are 7.1% in the naturally infected generation born before 1977 and 23.7% in the vaccinated generation born after 1978. Given "herd" immunity, we concluded that all vaccinated-generation persons should be administered additional vaccination regardless of sensitivity due to history, immunization, and PA or EIA antibody testing.
authors.affiliation: Chosei Health and Welfare Center.
authors.forename: Sadato
authors.initials: S
authors.lastname: Ichinohe
authors.forename: Tomoko
authors.initials: T
authors.lastname: Ogawa
mesh_terms: D000328:Adult; D000914:Antibodies, Viral / Q000097:blood*; D005178:Faculty; D005260:Female; D006801:Humans; D032521:Immunity, Herd; D008297:Male; D008457:Measles / Q000276:immunology / Q000517:prevention & control; D008458:Measles Vaccine; D008875:Middle Aged; D014611:Vaccination
chemical_list: D000914:Antibodies, Viral; D008458:Measles Vaccine