title: Palladium-catalyzed direct arylation of thiophenes bearing SO2R substituents.
abstract: The palladium-catalyzed direct arylation of SO(2)R-substituted thiophene derivatives was found to proceed regioselectively at C5 and in high yields using a variety of aryl bromides and as low as 0.5-0.1 mol % of phosphine-free Pd(OAc)(2) as the catalyst. For these reactions, sulfonyls, sulfonamides, or even a sulfonic ester as the thiophene substituents were successfully employed.
authors.affiliation: Institut Sciences Chimiques de Rennes, UMR 6226 CNRS, Université de Rennes Catalyse et Organometalliques, Campus de Beaulieu, 35042 Rennes, France.
authors.forename: Charles Beromeo
authors.initials: CB
authors.lastname: Bheeter
authors.forename: Jitendra K
authors.initials: JK
authors.lastname: Bera
authors.forename: Henri
authors.initials: H
authors.lastname: Doucet