title: Placental abruption, offspring sex, and birth outcomes in a large cohort of mothers.
abstract: OBJECTIVE
  To investigate stillbirth, neonatal, and perinatal death outcomes in pregnancies complicated by placental abruption, according to fetal sex.
  
  
  METHODS
  We utilized maternally linked cohort data files of singleton live births to mothers diagnosed with placental abruption during the period 1989 through 2005 (n = 10,014). Logistic regression models were employed to generate adjusted odd ratios and their 95% confidence intervals. Male babies served as the referent category.
  
  
  RESULTS
  The sex ratio at birth was 1.18. The overall prevalence of stillbirth, neonatal mortality, and perinatal mortality was 7.2%, 4.5%, and 11.8%, respectively. Placental abruption was less likely to occur in mothers carrying female pregnancies than mothers of male infants (adjusted odds ratio [95% confidence interval] = 0.89 [0.86-0.93]). There were no significant sex differences with regards to stillbirth, neonatal mortality, and perinatal mortality. Similar findings were observed for preterm and term infants.
  
  
  CONCLUSIONS
  Although a preponderance of male infants was discernable among mothers with placental abruption, no sex difference in fetal survival was observed among the offspring of the mothers affected by placental abruption.
authors.affiliation: Department of Preventive Medicine & Institute for Global Health, Vanderbilt University, Nashville, TN, USA.
authors.forename: Muktar H
authors.initials: MH
authors.lastname: Aliyu
authors.forename: Hamisu M
authors.initials: HM
authors.lastname: Salihu
authors.forename: Of'neil
authors.initials: O
authors.lastname: Lynch
authors.forename: Amina P
authors.initials: AP
authors.lastname: Alio
authors.forename: Phillip J
authors.initials: PJ
authors.lastname: Marty
mesh_terms: D000037:Abruptio Placentae; D005260:Female; D006801:Humans; D007223:Infant; D007226:Infant Mortality; D007231:Infant, Newborn; D016015:Logistic Models; D008297:Male; D054238:Perinatal Mortality; D011247:Pregnancy; D011256:Pregnancy Outcome; D012737:Sex Factors; D012744:Sex Ratio; D050497:Stillbirth / Q000453:epidemiology*; D016019:Survival Analysis