title: In vitro antimicrobial activity of methanolic leaf extract of Psidium guajava L.
abstract: OBJECTIVE
  This study was designed to examine the chemical composition and in vitro antimicrobial potential of methanolic extract of Psidium guajava Linn (Myrtaceae).
  
  
  METHODS
  The inhibitory effect of methanolic extract of P. guajava was tested against three bacterial and two fungal strains by using the paper disc diffusion method.
  
  
  RESULTS
  The methanolic extract exhibited antibacterial activity against E. coli with minimum inhibitory concentration, 0.78 μg/ml, minimum bactericidal concentration of 50 μg/ml, and appreciable antifungal activity with minimum inhibitory concentration of 12.5 μg/ml. Preliminary phytochemical analysis of methanolic extract revealed the presence of antimicrobial compounds such as flavonoids, steroids, and tannins, which may contribute for the antimicrobial action of P. guajava.
  
  
  CONCLUSIONS
  The extract was found to be bacteriostatic and fungistatic in action.
authors.affiliation: Department of Pharmaceutical Sciences, M.D. University, Rohtak, Haryana, India.
authors.forename: Anju
authors.initials: A
authors.lastname: Dhiman
authors.forename: Arun
authors.initials: A
authors.lastname: Nanda
authors.forename: Sayeed
authors.initials: S
authors.lastname: Ahmad
authors.forename: B
authors.initials: B
authors.lastname: Narasimhan