title: A naphthalene-based Al3+ selective fluorescent sensor for living cell imaging.
abstract: An efficient fluorescent Al(3+) receptor, N-(2-hydroxy-1-naphthalene)-N'-(2-(2-hydroxy-1-naphthalene)amino-ethyl)-ethane-1,2-diamine (L) has been synthesized by the condensation reaction between 2-hydroxy naphthaldehyde and diethylenetriamine. High selectivity and affinity of L towards Al(3+) in ethanol (EtOH) as well as in HEPES buffer at pH 7.4, makes it suitable to detect intracellular Al(3+) with fluorescence microscopy. Metal ions, viz. Li(+), Na(+), K(+), Mg(2+), Ca(2+), Mn(2+), Co(2+), Ni(2+), Cu(2+), Zn(2+), Ag(+), Cd(2+), Hg(2+) and Pb(2+) do not interfere. The lowest detection limit for Al(3+) is 3.0 × 10(-7) M and 1.0 × 10(-7) M in EtOH and HEPES buffer respectively.
authors.affiliation: Department of Chemistry, The University of Burdwan, Burdwan, 713104, West Bengal, India.
authors.forename: Animesh
authors.initials: A
authors.lastname: Sahana
authors.forename: Arnab
authors.initials: A
authors.lastname: Banerjee
authors.forename: Sudipta
authors.initials: S
authors.lastname: Das
authors.forename: Sisir
authors.initials: S
authors.lastname: Lohar
authors.forename: Debasis
authors.initials: D
authors.lastname: Karak
authors.forename: Bidisha
authors.initials: B
authors.lastname: Sarkar
authors.forename: Subhra Kanti
authors.initials: SK
authors.lastname: Mukhopadhyay
authors.forename: Asok K
authors.initials: AK
authors.lastname: Mukherjee
authors.forename: Debasis
authors.initials: D
authors.lastname: Das
mesh_terms: D000535:Aluminum / Q000032:analysis / Q000737:chemistry*; D002176:Candida albicans / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000138:chemical synthesis* / Q000737:chemistry; D008024:Ligands; D009682:Magnetic Resonance Spectroscopy; D008856:Microscopy, Fluorescence; D015394:Molecular Structure; D009281:Naphthalenes / Q000138:chemical synthesis* / Q000737:chemistry*
chemical_list: D005456:Fluorescent Dyes; D008024:Ligands; D009281:Naphthalenes; D000535:Aluminum