title: Composition of the essential oil constituents from leaves and stems of Korean Coriandrum sativum and their immunotoxicity activity on the Aedes aegypti L.
abstract: The leaves and stems of Coriandrum sativum were extracted and the essential oil composition and immunotoxicity effects were studied. The analyses were conducted by gas chromatography-mass spectroscopy (GC-MS), which revealed the essential oils of C. sativum leaves and stems. Thirty-nine components representing 99.62% of the total oil were identified from the leaves. The major components are cyclododecanol (23.11%), tetradecanal (17.86%), 2-dodecenal (9.93%), 1-decanol (7.24%), 13-tetradecenal (6.85%), 1-dodecanol (6.54%), dodecanal (5.16%), 1-undecanol (2.28%), and decanal (2.33%). Thirty-eight components representing 98.46% of the total oil were identified from the stems of the coriander. The major components are phytol (61.86%), 15-methyltricyclo[6.5.2(13,14),0(7,15)]-pentadeca-1,3,5,7,9,11,13-heptene (7.01%), dodecanal (3.18%), and 1-dodecanol (2.47%). The leaf oil had significant toxic effects against the larvae of Aedes aegypti with an LC₅₀ value of 26.93 ppm and an LC₉₀ value of 37.69 ppm and the stem oil has toxic effects against the larvae of A. aegypti with an LC₅₀ value of 29.39 ppm and an LC₉₀ value of 39.95 ppm. Also, the above data indicate that the major compounds may play an important role in the toxicity of essential oils.
authors.affiliation: Department of Applied Life Science, Konkuk University, Seoul, South Korea.
authors.forename: Ill-Min
authors.initials: IM
authors.lastname: Chung
authors.forename: Ateeque
authors.initials: A
authors.lastname: Ahmad
authors.forename: Sun-Jin
authors.initials: SJ
authors.lastname: Kim
authors.forename: Poornanand Madhava
authors.initials: PM
authors.lastname: Naik
authors.forename: Praveen
authors.initials: P
authors.lastname: Nagella
mesh_terms: D000330:Aedes / Q000254:growth & development*; D000818:Animals; D028526:Coriandrum / Q000737:chemistry*; D007306:Insecticides / Q000737:chemistry / Q000494:pharmacology*; D007723:Korea; D007814:Larva / Q000254:growth & development; D009822:Oils, Volatile / Q000737:chemistry / Q000494:pharmacology*; D018515:Plant Leaves / Q000737:chemistry*; D018547:Plant Stems / Q000737:chemistry*
chemical_list: D007306:Insecticides; D009822:Oils, Volatile