title: From benzodiazepines to peripheral and brain steroid biosynthesis.
abstract: From the biochemistry of testicular and adrenal steroids to the mysteries of brain steroid biosynthesis and from pharmacy and pharmacology to neuropharmacology and neurosciences were two transitions in my scientific career where Erminio (Mimo) Costa played a catalytic role. A review of the years and findings that contributed in our understanding of the link between benzodiazepines and neurosteroid biosynthesis that established the pharmacology of neurosteroidogenesis is a testimony to Dr. Costa's will to push the borders of knowledge that inspired us to challenge existing notions and paradigms.
authors.affiliation: The Research Institute of the McGill University Health Centre and the Department of Medicine, McGill University, Montreal General Hospital, 1650 Cedar Avenue, C10-148, Montreal, Quebec H3G 1A4, Canada. vassilios.papadopoulos@mcgill.ca
authors.forename: Vassilios
authors.initials: V
authors.lastname: Papadopoulos
mesh_terms: D000311:Adrenal Glands / Q000378:metabolism; D000818:Animals; D001569:Benzodiazepines / Q000494:pharmacology*; D001921:Brain / Q000378:metabolism*; D049673:History, 20th Century; D006801:Humans; D008297:Male; D009480:Neuropharmacology / Q000266:history / Q000379:methods; D009488:Neurosciences / Q000266:history / Q000379:methods; D013256:Steroids / Q000378:metabolism*; D013737:Testis / Q000378:metabolism
chemical_list: D013256:Steroids; D001569:Benzodiazepines