title: Natural products: promising resources for cancer drug discovery.
abstract: Natural products are important sources of anti-cancer lead molecules. Many successful anti-cancer drugs are natural products or their analogues. Many more are under clinical trials. The present review focuses on chemopreventive and anti-cancer activities of polar and non-polar extracts, semi purified fractions and pure molecules from terrestrial plants of India reported between 2005 and 2010 emphasizing possible mechanisms of action of pure molecules.
authors.affiliation: Council of Scientific and Industrial Research-Indian Institute of Chemical Biology, 4, Raja S.C. Mullick Road, Kolkata-700 032, India.
authors.forename: Susmita
authors.initials: S
authors.lastname: Mondal
authors.forename: Santu
authors.initials: S
authors.lastname: Bandyopadhyay
authors.forename: Mrinal K
authors.initials: MK
authors.lastname: Ghosh
authors.forename: Sibabrata
authors.initials: S
authors.lastname: Mukhopadhyay
authors.forename: Siddhartha
authors.initials: S
authors.lastname: Roy
authors.forename: Chitra
authors.initials: C
authors.lastname: Mandal
mesh_terms: D000818:Animals; D016588:Anticarcinogenic Agents / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use*; D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use*; D001688:Biological Products / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use; D055808:Drug Discovery; D006801:Humans; D007194:India; D009369:Neoplasms / Q000188:drug therapy* / Q000517:prevention & control; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use*; D010946:Plants, Medicinal / Q000737:chemistry*
chemical_list: D016588:Anticarcinogenic Agents; D000972:Antineoplastic Agents, Phytogenic; D001688:Biological Products; D010936:Plant Extracts