title: Detection of masses in mammogram images using CNN, geostatistic functions and SVM.
abstract: Breast cancer occurs with high frequency among the world's population and its effects impact the patients' perception of their own sexuality and their very personal image. This work presents a computational methodology that helps specialists detect breast masses in mammogram images. The first stage of the methodology aims to improve the mammogram image. This stage consists in removing objects outside the breast, reducing noise and highlighting the internal structures of the breast. Next, cellular neural networks are used to segment the regions that might contain masses. These regions have their shapes analyzed through shape descriptors (eccentricity, circularity, density, circular disproportion and circular density) and their textures analyzed through geostatistic functions (Ripley's K function and Moran's and Geary's indexes). Support vector machines are used to classify the candidate regions as masses or non-masses, with sensitivity of 80%, rates of 0.84 false positives per image and 0.2 false negatives per image, and an area under the ROC curve of 0.87.
authors.affiliation: Federal University of Maranhão - UFMA, Applied Computing Group - NCA, Av. dos Portugueses, SN, Campus do Bacanga, Bacanga 65085-580, São Luís, MA, Brazil. wenersampaio@yahoo.com.br
authors.forename: Wener Borges
authors.initials: WB
authors.lastname: Sampaio
authors.forename: Edgar Moraes
authors.initials: EM
authors.lastname: Diniz
authors.forename: Aristófanes Corrêa
authors.initials: AC
authors.lastname: Silva
authors.forename: Anselmo Cardoso
authors.initials: AC
authors.lastname: de Paiva
authors.forename: Marcelo
authors.initials: M
authors.lastname: Gattass
mesh_terms: D000465:Algorithms; D001943:Breast Neoplasms / Q000000981:diagnostic imaging*; D016000:Cluster Analysis; D016208:Databases, Factual; D005260:Female; D006801:Humans; D008327:Mammography / Q000379:methods*; D016571:Neural Networks, Computer; D012372:ROC Curve; D011857:Radiographic Image Interpretation, Computer-Assisted / Q000379:methods*; D012680:Sensitivity and Specificity