title: Dramatic response to levetiracetam in post-ischaemic Holmes' tremor.
abstract: Holmes' tremor refers to an unusual combination of rest, postural and kinetic tremor of extremities. Common causes of Holmes' tremor include stroke, trauma, vascular malformations and multiple sclerosis, with lesions involving the thalamus, brain stem or cerebellum. Although some drugs (eg, levodopa and dopaminergic drugs, clonazepam and propranolol) have been occasionally reported to give some benefit, medical treatment of Holmes' tremor is unsatisfactory, and many patients require thalamic surgery to achieve satisfactory control. We report a patient in whom post-ischaemic Holmes' tremor dramatically responded to levetiracetam treatment.
authors.affiliation: Federico II University, Via Pansini 5, Naples, 80131, Italy.
authors.forename: P
authors.initials: P
authors.lastname: Striano
authors.forename: Andrea
authors.initials: A
authors.lastname: Elefante
authors.forename: Antonietta
authors.initials: A
authors.lastname: Coppola
authors.forename: Fabio
authors.initials: F
authors.lastname: Tortora
authors.forename: Federico
authors.initials: F
authors.lastname: Zara
authors.forename: Carlo
authors.initials: C
authors.lastname: Minetti