title: Lymphocyte signaling converges on microtubules.
abstract: Movement of immunoreceptor microclusters tunes lymphocyte activation, but the underlying mechanisms are incompletely understood. In this issue of Immunity, Schnyder et al. (2011) and Hashimoto-Tane et al. (2011) show that cytoplasmic dynein drives microcluster centralization along microtubules.
authors.affiliation: Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia and University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.
authors.forename: Alexander
authors.initials: A
authors.lastname: Babich
authors.forename: Janis K
authors.initials: JK
authors.lastname: Burkhardt