title: Hydrocephalus due to diffuse villous hyperplasia of the choroid plexus.
abstract: An 8-month-old female presented with hydrocephalus caused by cerebrospinal fluid (CSF) overproduction due to bilateral choroid plexus enlargement, which was clinically diagnosed as diffuse villous hyperplasia of the choroid plexus, but differentiation from bilateral choroid plexus papilloma was difficult. She initially underwent ventriculoperitoneal shunt surgery, but developed marked retention of ascites. Therefore, the peritoneal end of the shunt was removed for external drainage, but excessive CSF (1,500 ml/day) was collected. Computed tomography and magnetic resonance imaging revealed marked symmetric enhancement of the choroid plexuses in the bilateral lateral ventricles. Thallium-201 chloride single-photon emission computed tomography showed pronounced uptake on both early and delayed images, and good washout. CSF examination revealed no abnormalities such as atypical cells, and a ventriculoatrial shunt was inserted, achieving good control of the hydrocephalus.
authors.affiliation: Department of Neurosurgery, Asahikawa Medical College, Hokkaido, Japan. anei@asahikawa-med.ac.jp
authors.forename: Ryogo
authors.initials: R
authors.lastname: Anei
authors.forename: Yoshimitsu
authors.initials: Y
authors.lastname: Hayashi
authors.forename: Satoru
authors.initials: S
authors.lastname: Hiroshima
authors.forename: Nobuyuki
authors.initials: N
authors.lastname: Mitsui
authors.forename: Ryosuke
authors.initials: R
authors.lastname: Orimoto
authors.forename: Genki
authors.initials: G
authors.lastname: Uemori
authors.forename: Masato
authors.initials: M
authors.lastname: Saito
authors.forename: Masao
authors.initials: M
authors.lastname: Sato
authors.forename: Hajime
authors.initials: H
authors.lastname: Wada
authors.forename: Akira
authors.initials: A
authors.lastname: Hododuka
authors.forename: Kyousuke
authors.initials: K
authors.lastname: Kamada
mesh_terms: D016543:Central Nervous System Neoplasms / Q000473:pathology* / Q000601:surgery; D002555:Cerebrospinal Fluid / Q000378:metabolism; D002557:Cerebrospinal Fluid Shunts / Q000295:instrumentation / Q000379:methods*; D002831:Choroid Plexus / Q000473:pathology*; D005260:Female; D006801:Humans; D006849:Hydrocephalus / Q000209:etiology / Q000601:surgery*; D006965:Hyperplasia / Q000150:complications; D007223:Infant; D020547:Lateral Ventricles / Q000098:blood supply* / Q000378:metabolism / Q000473:pathology; D008871:Microvilli / Q000473:pathology; D020288:Papilloma, Choroid Plexus / Q000473:pathology* / Q000601:surgery; D016896:Treatment Outcome