title: The effect of an education programme (MEDIAS 2 ICT) involving intensive insulin treatment for people with type 2 diabetes.
abstract: OBJECTIVE
  In a randomized, multi-centre trial, the effect of an education programme (MEDIAS 2 ICT) involving intensive insulin treatment for people with type 2 diabetes was compared with an established education programme as an active comparator condition (ACC).
  
  
  METHODS
  We investigated whether MEDIAS 2 ICT was non-inferior to ACC in overall glycaemic control. Secondary outcomes were the diabetes-related distress, diabetes knowledge, quality of life, self-care behavior, lipids, blood pressure and weight.
  
  
  RESULTS
  186 subjects were randomized. After a six month follow-up the mean HbA1c decrease was 0.37% (from 8.2±1.1% to 7.8±1.5%) in the ACC and 0.63% (from 8.5±1.5% to 7.9±1.2%) in MEDIAS 2 ICT. The mean difference between both groups was -0.26% (95% CI -0.63 to -0.14) in favor of MEDIAS 2 ICT. This result was within the predefined limit for non-inferiority. Diabetes-related distress was significantly more reduced in MEDIAS 2 ICT (-3.4±7.1) than in ACC (0.4±9.0; p=0.31).
  
  
  CONCLUSIONS
  MEDIAS 2 ICT is as effective in lowering HbA1c as previously established education programmes, but showed superiority in reducing diabetes-related distress.
  
  
  CONCLUSIONS
  MEDIAS 2 ICT provides an alternative for education of people with type 2 diabetes treated by multiple injection therapy.
authors.affiliation: Research Institute of the Diabetes Academy Mergentheim (FIDAM), Bad Mergentheim, Germany. hermanns@diabetes-zentrum.de
authors.forename: Norbert
authors.initials: N
authors.lastname: Hermanns
authors.forename: Bernhard
authors.initials: B
authors.lastname: Kulzer
authors.forename: Berthold
authors.initials: B
authors.lastname: Maier
authors.forename: Marina
authors.initials: M
authors.lastname: Mahr
authors.forename: Thomas
authors.initials: T
authors.lastname: Haak
mesh_terms: D000328:Adult; D000368:Aged; D015190:Blood Glucose Self-Monitoring; D001794:Blood Pressure; D001835:Body Weight; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000628:therapy*; D005260:Female; D005500:Follow-Up Studies; D006442:Glycated Hemoglobin / Q000032:analysis*; D006266:Health Education / Q000379:methods; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D007004:Hypoglycemic Agents / Q000008:administration & dosage*; D007328:Insulin / Q000008:administration & dosage*; D008297:Male; D008875:Middle Aged; D010353:Patient Education as Topic / Q000379:methods*; D011446:Prospective Studies; D012648:Self Care
chemical_list: D006442:Glycated Hemoglobin; D007004:Hypoglycemic Agents; D007328:Insulin