title: Recurrent corneal hypertrophic scar after laser-assisted subepithelial keratectomy with mitomycin C treatment.
abstract: OBJECTIVE
  To report recurrent corneal hypertrophic scar after laser-assisted subepithelial keratectomy (LASEK) with mitomycin C treatment.
  
  
  METHODS
  Two patients experienced decreased visual acuity in 1 eye arising from elevated corneal opacity about 12 months after uneventful LASEK with intraoperative mitomycin C application. The elevated opacities were easily removed mechanically.
  
  
  RESULTS
  Pathologic examinations showed irregular arrangement of collagen fibers and myofibroblasts, diagnosed as hypertrophic scars. The lesions recurred at about 4-month intervals, despite repeated debridement with and without prophylactic mitomycin C treatment.
  
  
  CONCLUSIONS
  Recurrent corneal hypertrophic scar may be a rare complication after LASEK treatment with mitomycin C application.
authors.affiliation: Department of Ophthalmology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
authors.forename: Jae-Hyung
authors.initials: JH
authors.lastname: Kim
authors.forename: Myoung Joon
authors.initials: MJ
authors.lastname: Kim
authors.forename: Dong Yoon
authors.initials: DY
authors.lastname: Kim
authors.forename: Jae Yong
authors.initials: JY
authors.lastname: Kim
authors.forename: Hungwon
authors.initials: H
authors.lastname: Tchah
mesh_terms: D000328:Adult; D000477:Alkylating Agents / Q000008:administration & dosage*; D017439:Cicatrix, Hypertrophic / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D003318:Corneal Opacity / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D003646:Debridement; D005260:Female; D006801:Humans; D049008:Keratectomy, Subepithelial, Laser-Assisted; D008297:Male; D033401:Microscopy, Acoustic; D016685:Mitomycin / Q000008:administration & dosage*; D011183:Postoperative Complications; D012008:Recurrence; D014792:Visual Acuity / Q000187:drug effects; D055815:Young Adult
chemical_list: D000477:Alkylating Agents; D016685:Mitomycin