title: Zn(II) and Cd(II)-based complexes for probing the enzymatic hydrolysis of Na4P2O7 by alkaline phosphatase in physiological conditions.
abstract: Newly synthesized Zn(II) and Cd(II)-based complexes show unique selectivity towards inorganic pyrophosphate (PPi) in 100% aqueous medium at pH = 7.4 and act as a "turn-on" and "turn-off" real-time assay, respectively, for the evaluation of the enzymatic activity of alkaline phosphatase.
authors.affiliation: Central Salt & Marine Chemicals Research Institute (CSIR), Bhavnaga, 364002, Gujarat, India.
authors.forename: Priyadip
authors.initials: P
authors.lastname: Das
authors.forename: Sourish
authors.initials: S
authors.lastname: Bhattacharya
authors.forename: Sandhya
authors.initials: S
authors.lastname: Mishra
authors.forename: Amitava
authors.initials: A
authors.lastname: Das
mesh_terms: D000469:Alkaline Phosphatase / Q000378:metabolism*; D002104:Cadmium / Q000737:chemistry*; D011756:Diphosphates / Q000378:metabolism*; D057075:Enzyme Assays / Q000379:methods*; D005456:Fluorescent Dyes / Q000138:chemical synthesis / Q000737:chemistry*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D006868:Hydrolysis; D009942:Organometallic Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D015032:Zinc / Q000737:chemistry*
chemical_list: D011756:Diphosphates; D005456:Fluorescent Dyes; D009942:Organometallic Compounds; D002104:Cadmium; D000469:Alkaline Phosphatase; D015032:Zinc; C003319:sodium pyrophosphate