title: A Clinical Study of a Cell-Based MAGE-A3 Active Immunotherapy in Advanced Melanoma Patients.
abstract: In this bi-institutional study, twenty-three stage IIIC-IV MAGE-A3(+) melanoma patients were vaccinated with M3TK-GML biweekly at three dose levels, with a subsequent phase of vaccinations at the maximum dose level. Anti-MAGE-A3 and anti-TK T cells were assessed by in vitro assay and delayed-type hypersensitivity skin testing.
authors.affiliation: 1. Cancer Gene Therapy Unit, San Raffaele Scientific Institute, via Olgettina 60, 20132, Milan, Italy;
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Russo
authors.forename: Francesca
authors.initials: F
authors.lastname: Lunghi
authors.forename: Raffaella
authors.initials: R
authors.lastname: Fontana
authors.forename: Marco
authors.initials: M
authors.lastname: Bregni