title: Tuberculosis and profound hypovitaminosis D in an infant.
abstract: A young infant presented with a febrile respiratory illness, irritability, and failure to thrive. Clinical evaluation identified that he had profound hypovitaminosis D with severe hypocalcemia and active pulmonary tuberculosis. We review the literature and discuss the current state of knowledge of the interrelationship between Mycobacterium infection and vitamin D status, and its implication to pediatricians.
authors.affiliation: Johns Hopkins Hospital, McKusick-Nathans Institute of Genetic Medicine, Baltimore, MD 21287, USA. aelias2@jhmi.edu
authors.forename: Abdallah F
authors.initials: AF
authors.lastname: Elias
authors.forename: Joel
authors.initials: J
authors.lastname: Dunn
authors.forename: Mark K
authors.initials: MK
authors.lastname: Huntington
mesh_terms: D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use; D000995:Antitubercular Agents / Q000008:administration & dosage* / Q000627:therapeutic use; D006801:Humans; D006996:Hypocalcemia / Q000097:blood* / Q000188:drug therapy / Q000208:ethnology / Q000382:microbiology / Q000473:pathology; D007223:Infant; D008297:Male; D009169:Mycobacterium tuberculosis / Q000187:drug effects* / Q000502:physiology; D013397:Sudan / Q000208:ethnology; D014397:Tuberculosis, Pulmonary / Q000097:blood / Q000188:drug therapy / Q000208:ethnology / Q000382:microbiology* / Q000473:pathology; D014481:United States / Q000453:epidemiology; D014807:Vitamin D / Q000008:administration & dosage / Q000378:metabolism*; D014808:Vitamin D Deficiency / Q000097:blood* / Q000188:drug therapy / Q000208:ethnology / Q000382:microbiology / Q000473:pathology
chemical_list: D000900:Anti-Bacterial Agents; D000995:Antitubercular Agents; D014807:Vitamin D