title: Granulocytic sarcoma, an undiagnosed leukemia, initially manifested as paralysis.
abstract: Granulocytic sarcoma (GS) may be a presenting sign of myelogenous leukemia. Occasionally, an extramedullary neoplasm composed from myelocytic precursor cells occurs in patients without evidence of leukemia. Rarely, undiagnosed leukemia occurs initially manifesting with paralysis to spinal cord GS. We present a case report of 20-year-old girl with an undiagnosed leukemia, initially manifesting as paralysis. En bloc spondylectomy with chemotherapy postoperatively constituted the treatment of choice for this tumor. After two courses of chemotherapy, the patient made a good postoperative recovery with notable bilateral lower extremity improvement.
authors.affiliation: Department of Orthopaedics, Changzhou Traditional Chinese Medical Hospital, Nanjing University of Traditional Chinese Medicine, Changzhou, Jiangsu Province, China.
authors.forename: Jianda
authors.initials: J
authors.lastname: Xu
authors.forename: Hong
authors.initials: H
authors.lastname: Zhao
authors.forename: Tao
authors.initials: T
authors.lastname: Jiang
authors.forename: Yi
authors.initials: Y
authors.lastname: Gao
authors.forename: Chong
authors.initials: C
authors.lastname: Zheng
authors.forename: Bin
authors.initials: B
authors.lastname: Wang
authors.forename: Yuxing
authors.initials: Y
authors.lastname: Qu
mesh_terms: D000328:Adult; D000970:Antineoplastic Agents / Q000627:therapeutic use; D001853:Bone Marrow / Q000473:pathology; D019299:Decompression, Surgical; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000150:complications* / Q000175:diagnosis*; D007958:Leukocyte Count; D017116:Low Back Pain / Q000209:etiology; D008279:Magnetic Resonance Imaging; D010243:Paralysis / Q000209:etiology* / Q000601:surgery; D023981:Sarcoma, Myeloid / Q000150:complications* / Q000175:diagnosis* / Q000601:surgery; D013120:Spinal Cord Neoplasms / Q000150:complications* / Q000175:diagnosis* / Q000601:surgery
chemical_list: D000970:Antineoplastic Agents