title: Two induced fungal polyketide pathways converge into antiproliferative spiroanthrones.
authors.affiliation: Department of Biomolecular Chemistry, Leibniz Institute for Natural Product Research and Infection Biology, Beutenbergstrasse 11a, 07745 Jena, Germany.
authors.forename: Kirstin
authors.initials: K
authors.lastname: Scherlach
authors.forename: Anindita
authors.initials: A
authors.lastname: Sarkar
authors.forename: Volker
authors.initials: V
authors.lastname: Schroeckh
authors.forename: Hans-Martin
authors.initials: HM
authors.lastname: Dahse
authors.forename: Martin
authors.initials: M
authors.lastname: Roth
authors.forename: Axel A
authors.initials: AA
authors.lastname: Brakhage
authors.forename: Uwe
authors.initials: U
authors.lastname: Horn
authors.forename: Christian
authors.initials: C
authors.lastname: Hertweck
mesh_terms: D000880:Anthraquinones / Q000737:chemistry / Q000378:metabolism* / Q000494:pharmacology; D000970:Antineoplastic Agents / Q000737:chemistry / Q000378:metabolism* / Q000494:pharmacology; D001233:Aspergillus nidulans / Q000235:genetics / Q000378:metabolism*; D019149:Bioreactors; D001709:Biotechnology / Q000379:methods*; D005285:Fermentation; D020869:Gene Expression Profiling; D015966:Gene Expression Regulation, Fungal; D006801:Humans; D020014:K562 Cells; D009682:Magnetic Resonance Spectroscopy; D053858:Metabolic Networks and Pathways / Q000502:physiology*; D009584:Nitrogen / Q000172:deficiency*; D048630:Polyketide Synthases / Q000235:genetics / Q000378:metabolism*; D012118:Resorcinols / Q000378:metabolism; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; D015533:Transcriptional Activation
chemical_list: D000880:Anthraquinones; D000970:Antineoplastic Agents; D012118:Resorcinols; C501612:orsellinic acid; D048630:Polyketide Synthases; D009584:Nitrogen