title: Genome sequence of the thermophilic strain Bacillus coagulans 2-6, an efficient producer of high-optical-purity L-lactic acid.
abstract: Bacillus coagulans 2-6 is an efficient producer of lactic acid. The genome of B. coagulans 2-6 has the smallest genome among the members of the genus Bacillus known to date. The frameshift mutation at the start of the d-lactate dehydrogenase sequence might be responsible for the production of high-optical-purity l-lactic acid.
authors.affiliation: State Key Laboratory of Microbial Metabolism and School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, People’s Republic of China.
authors.forename: Fei
authors.initials: F
authors.lastname: Su
authors.forename: Bo
authors.initials: B
authors.lastname: Yu
authors.forename: Jibin
authors.initials: J
authors.lastname: Sun
authors.forename: Hong-Yu
authors.initials: HY
authors.lastname: Ou
authors.forename: Bo
authors.initials: B
authors.lastname: Zhao
authors.forename: Limin
authors.initials: L
authors.lastname: Wang
authors.forename: Jiayang
authors.initials: J
authors.lastname: Qin
authors.forename: Hongzhi
authors.initials: H
authors.lastname: Tang
authors.forename: Fei
authors.initials: F
authors.lastname: Tao
authors.forename: Michael
authors.initials: M
authors.lastname: Jarek
authors.forename: Maren
authors.initials: M
authors.lastname: Scharfe
authors.forename: Cuiqing
authors.initials: C
authors.lastname: Ma
authors.forename: Yanhe
authors.initials: Y
authors.lastname: Ma
authors.forename: Ping
authors.initials: P
authors.lastname: Xu
mesh_terms: D001407:Bacillus / Q000235:genetics* / Q000378:metabolism*; D002874:Chromosome Mapping; D005285:Fermentation; D016368:Frameshift Mutation; D016680:Genome, Bacterial; D045022:Lactate Dehydrogenases / Q000235:genetics / Q000378:metabolism; D019344:Lactic Acid / Q000096:biosynthesis*; D008969:Molecular Sequence Data; D010957:Plasmids
chemical_list: D019344:Lactic Acid; D045022:Lactate Dehydrogenases; C071195:D-lactate dehydrogenase