title: OCT assessment of morphological changes of the optic nerve head and macula in idiopathic intracranial hypertension.
abstract: OBJECTIVE
  To assess the morphologic changes of the optic nerve head and macula in patients with idiopathic intracranial hypertension (IIH) with optical coherence tomography (OCT).
  
  
  METHODS
  Data was extracted from the medical records and Stratus OCT images of IIH patients.
  
  
  RESULTS
  Ninety-one eyes of 48 IIH patients were divided into 3 groups according to their clinical optic disc appearance. Average retinal nerve fiber layer (RNFL) thickness was statistically different between the groups: normal optic disc/mild elevation group (N=20) - 89 μm (95% CI, 80-98 μm), mild elevation group (N=51) - 109 μm (95% CI, 101-117 μm), and papilledema group (N=20) 124 μm (95% CI, 100-153 μm) (P=0.004). Fast macular thickness map did not demonstrate a significant difference between the groups for most measured macular areas (N=49 eyes).
  
  
  CONCLUSIONS
  Peripapillary RNFL measurements correlated with the clinical appearance of the optic discs, suggesting that OCT may assist in the follow up of IIH patients.
authors.affiliation: Department of Ophthalmology, Tel Aviv Sourasky Medical Center, 6 Weizmann Street, Tel Aviv 64239, Israel. mwaisbourd@hotmail.com
authors.forename: Michael
authors.initials: M
authors.lastname: Waisbourd
authors.forename: Igal
authors.initials: I
authors.lastname: Leibovitch
authors.forename: Dafna
authors.initials: D
authors.lastname: Goldenberg
authors.forename: Anat
authors.initials: A
authors.lastname: Kesler
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000704:Analysis of Variance; D005260:Female; D006801:Humans; D008266:Macula Lutea / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009898:Optic Disk / Q000473:pathology; D009900:Optic Nerve / Q000473:pathology*; D010211:Papilledema / Q000473:pathology; D011559:Pseudotumor Cerebri / Q000473:pathology*; D055351:Retinal Neurons / Q000473:pathology; D012189:Retrospective Studies; D041623:Tomography, Optical Coherence / Q000379:methods*; D014792:Visual Acuity; D014794:Visual Fields; D055815:Young Adult