title: Acute hepatitis induced by glatiramer acetate.
abstract: Glatiramer acetate, a mixture of synthetic polypeptides able to prevent autoimmune encephalomyelitis in experimental models, is used as a treatment for patients with active relapsing-remitting multiple sclerosis. We report one case of glatiramer acetate induced hepatitis. Liver biopsy was consistent with a diagnosis of drug induced hepatitis and alanine aminotransferase returned to normal values after treatment discontinuation. The present case should serve as a warning that glatiramer acetate may cause acute liver disease.
authors.affiliation: Hopital de Jolimont, Service d'Hépato-gastroentérologie, Rue Ferrer, 159, Haine-Saint-Paul, 7100, Belgium.
authors.forename: Pierre
authors.initials: P
authors.lastname: Deltenre
authors.forename: Marie-Odile
authors.initials: MO
authors.lastname: Peny
authors.forename: André
authors.initials: A
authors.lastname: Dufour
authors.forename: Mohamed El
authors.initials: ME
authors.lastname: Nady
authors.forename: Jean
authors.initials: J
authors.lastname: Henrion