title: [The prognostic value of tumor cells blood circulation after liver surgery for cancer lesions].
abstract: The study aimed to prove the prognostic meaning of micrometastases blood circulation during liver resections for cancer lesions. 33 patients took part in the study. Circulating micrometastases were detected in blood using immunocytological method with pancytoceratine antibodies KL-1 and CAM 5.2. The majority of patients had colon cancer liver metastases (72,7%). Blood was sampled once in 8 patients, the rest 25 patients had double sampling: before and after liver mobilization. Patients with multiple liver metastases demonstrated tumor cells circulation more often. Of 58 tests, 25 were positive for tumor cells. 3-year survival in those patients was 45,7 ± 13,1%, 5-year survival was 24,4 ± 13,3%. Survival rates for patients with no circulating tumor cells detected were significantly higher.
authors.forename: Iu I
authors.initials: IuI
authors.lastname: Patiutko
authors.forename: N N
authors.initials: NN
authors.lastname: Tupitsyn
authors.forename: I V
authors.initials: IV
authors.lastname: Sagaĭdak
authors.forename: D V
authors.initials: DV
authors.lastname: Podluzhnyĭ
authors.forename: A L
authors.initials: AL
authors.lastname: Pylev
authors.forename: D A
authors.initials: DA
authors.lastname: Zabezhinskiĭ
mesh_terms: D003110:Colonic Neoplasms / Q000097:blood / Q000473:pathology; D003452:Cryosurgery; D004764:Enterohepatic Circulation; D005434:Flow Cytometry; D006498:Hepatectomy / Q000009:adverse effects / Q000379:methods*; D006801:Humans; D006979:Hyperthermia, Induced; D007150:Immunohistochemistry; D007633:Keratins / Q000378:metabolism*; D008099:Liver / Q000473:pathology / Q000601:surgery; D008113:Liver Neoplasms / Q000097:blood* / Q000175:diagnosis* / Q000556:secondary / Q000628:therapy; D009360:Neoplastic Cells, Circulating / Q000378:metabolism / Q000473:pathology; D016133:Polymerase Chain Reaction; D011237:Predictive Value of Tests; D011379:Prognosis; D015996:Survival Rate; D014656:Vascular Surgical Procedures
chemical_list: D007633:Keratins