title: The cat that caught the canary: what to do with single-molecule trapping.
abstract: It has recently become possible to trap individual fluorescent biomolecules in aqueous solution by using real-time tracking and active feedback to suppress Brownian motion. We propose areas of investigation in which anti-Brownian electrokinetic (ABEL) trapping of single molecules is likely to lead to significant new insights into biomolecular dynamics.
authors.affiliation: Harvard University, Cambridge, Massachusetts 02138, USA. cohen@chemistry.harvard.edu
authors.forename: Adam E
authors.initials: AE
authors.lastname: Cohen
authors.forename: Alexander P
authors.initials: AP
authors.lastname: Fields
mesh_terms: D008856:Microscopy, Fluorescence; D009038:Motion; D049329:Nanostructures / Q000737:chemistry; D013499:Surface Properties