title: The role of three-dimensional imaging reconstruction to measure the corpus callosum: comparison with direct mid-sagittal views.
abstract: OBJECTIVE
  To determine the accuracy of measuring the corpus callosum (CC) length in reconstructed mid-sagittal views obtained by 3D multiplanar manipulations or volume contrast imaging in the C-plane (VCI-C) in comparison to measurements obtained by direct mid-sagittal view.
  
  
  METHODS
  Forty-six normal fetuses were examined by 2D and 3D ultrasound between 23 and 32 weeks of gestation. Direct mid-sagittal views were obtained by either the transabdominal or/and the transvaginal approach. 3D reconstructed mid-sagittal views were obtained by either 3D multiplanar manipulations or VCI-C. The CC length was measured in direct mid-sagittal views and in 3D reconstructed mid-sagittal views.
  
  
  RESULTS
  One hundred and thirty ultrasound examinations were performed. In 118 cases (91%) it was possible to obtain both a direct and a 3D reconstructed mid-sagittal view. Measurements of the CC length in direct mid-sagittal views correlated significantly with the measurements in reconstructed mid-sagittal views when the region underneath the comma-shaped echogenic structure was measured, but correlated poorly when this echogenic structure was included.
  
  
  CONCLUSIONS
  Reconstructed mid-sagittal views obtained by 3D multiplanar manipulations or by VCI-C are valid approaches for measuring CC length. In these views the CC should be measured as the region underneath the comma-shaped echogenic structure.
authors.affiliation: Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, Braga, Portugal. rui.miguelote@gmail.com
authors.forename: R F
authors.initials: RF
authors.lastname: Miguelote
authors.forename: B
authors.initials: B
authors.lastname: Vides
authors.forename: R F
authors.initials: RF
authors.lastname: Santos
authors.forename: J A
authors.initials: JA
authors.lastname: Palha
authors.forename: A
authors.initials: A
authors.lastname: Matias
authors.forename: N
authors.initials: N
authors.lastname: Sousa
mesh_terms: D003337:Corpus Callosum / Q000000981:diagnostic imaging* / Q000196:embryology*; D005260:Female; D005865:Gestational Age; D006801:Humans; D007091:Image Processing, Computer-Assisted; D021621:Imaging, Three-Dimensional / Q000379:methods; D011247:Pregnancy; D016216:Ultrasonography, Prenatal / Q000379:methods*