title: [Invasive candidiasis in liver transplant recipient: early rescue antifungal treatment].
abstract: BACKGROUND
  Some liver transplant recipients could be at risk for candidemia or invasive candidiasis during the immediate postoperative period after transplantation. Prophylaxis is the best strategy to reduce the incidence of invasive fungal infection caused by Candida species in high-risk liver transplant recipients (HR-LTR), but in cases of suspected breakthrough invasive fungal infection due to Candida, both a rapid diagnosis process and early antifungal treatment are the most important factors impacting on the prognosis.
  
  
  METHODS
  We report a case of early rescue treatment with anidulafungin in a HR-LTR with complicated postoperative course. We discuss risk factors, prophylaxis, sensitivity of biomarkers, and characteristics of antifungal management.
  
  
  CONCLUSIONS
  Early rescue antifungal treatment using candins improves the prognosis in HR-LTR suffering from invasive candidiasis.
authors.affiliation: Servicio de Medicina Intensiva, Hospital Universitario Reina Sofía, Córdoba, España. juancarlos.pozo@ono.com
authors.forename: Juan Carlos
authors.initials: JC
authors.lastname: Pozo-Laderas
authors.forename: Antonio
authors.initials: A
authors.lastname: Pontes-Moreno
mesh_terms: D058186:Acute Kidney Injury / Q000150:complications / Q000628:therapy; D000328:Adult; D000077612:Anidulafungin; D000935:Antifungal Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D016470:Bacteremia / Q000209:etiology; D016063:Blood Loss, Surgical; D058387:Candidemia / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D003428:Cross Infection / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology* / Q000382:microbiology; D042241:Early Diagnosis; D054714:Echinocandins / Q000008:administration & dosage / Q000627:therapeutic use*; D019698:Hepatitis C, Chronic / Q000150:complications / Q000601:surgery; D006801:Humans; D016867:Immunocompromised Host; D008104:Liver Cirrhosis, Alcoholic / Q000150:complications / Q000601:surgery; D016031:Liver Transplantation; D008297:Male; D055624:Methicillin-Resistant Staphylococcus aureus / Q000302:isolation & purification; D009894:Opportunistic Infections / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology* / Q000382:microbiology; D011183:Postoperative Complications / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology* / Q000382:microbiology; D006435:Renal Dialysis; D012086:Reoperation; D012306:Risk; D013203:Staphylococcal Infections / Q000209:etiology
chemical_list: D000935:Antifungal Agents; D054714:Echinocandins; D000077612:Anidulafungin