title: 3.0T MR-guided laser ablation of a prostate cancer recurrence in the postsurgical prostate bed.
abstract: Biochemical recurrence of prostate cancer after definitive therapy with radical prostatectomy occurs in 25%-30% of cases. The first known case of magnetic resonance (MR) imaging-guided ablation using laser interstitial thermal therapy (LITT) for locally recurrent prostate cancer after radical prostatectomy is presented. Using 3.0T MR guidance, two laser applicators were placed via a transperineal approach. Laser ablation was performed using MR thermometry to determine the ablation endpoint and lesion coverage. Dynamic contrast-enhanced MR imaging after the procedure showed no definitive abnormal enhancement. The patient had no change in continence or potency after the procedure.
authors.affiliation: Department of Radiology, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA. woodrum.david@mayo.edu
authors.forename: David A
authors.initials: DA
authors.lastname: Woodrum
authors.forename: Lance A
authors.initials: LA
authors.lastname: Mynderse
authors.forename: Krzysztof R
authors.initials: KR
authors.lastname: Gorny
authors.forename: Kimberly K
authors.initials: KK
authors.lastname: Amrami
authors.forename: Roger J
authors.initials: RJ
authors.lastname: McNichols
authors.forename: Matthew R
authors.initials: MR
authors.lastname: Callstrom
mesh_terms: D000230:Adenocarcinoma / Q000276:immunology / Q000473:pathology / Q000601:surgery*; D006801:Humans; D053685:Laser Therapy; D053783:Magnetic Resonance Imaging, Interventional; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D009367:Neoplasm Staging; D017430:Prostate-Specific Antigen / Q000097:blood; D011468:Prostatectomy; D011471:Prostatic Neoplasms / Q000276:immunology / Q000473:pathology / Q000601:surgery*; D012086:Reoperation; D013817:Thermography; D016896:Treatment Outcome
chemical_list: D017430:Prostate-Specific Antigen