title: Improvement of absorption and scattering discrimination by selection of sensitive points on temporal profile in diffuse optical tomography.
abstract: We present a new method allowing the reconstruction of 3D time-domain diffuse optical tomography images, based on the time-dependent diffusion equation and an iterative algorithm (ART) using specific points on the temporal profiles. The first advantage of our method versus the full time-resolved scheme consists in considerably reducing the inverse problem resolution time. Secondly, in the presence of scattering heterogeneities, our method provides images of better quality comparatively to classical methods using full-time data or the first moments of the profiles.
authors.affiliation: Laboratoire d’Imagerie et de Neurosciences Cognitives, UMR 7237, Université de Strasbourg/CNRS, 4 rue Kirschleger, 67085 Strasbourg Cedex, France. farouk.nouizi@unistra.fr
authors.forename: Farouk
authors.initials: F
authors.lastname: Nouizi
authors.forename: Murielle
authors.initials: M
authors.lastname: Torregrossa
authors.forename: Renee
authors.initials: R
authors.lastname: Chabrier
authors.forename: Patrick
authors.initials: P
authors.lastname: Poulet
mesh_terms: D000042:Absorption; D000465:Algorithms; D000818:Animals; D003198:Computer Simulation; D006801:Humans; D008962:Models, Theoretical; D009369:Neoplasms / Q000175:diagnosis; D019047:Phantoms, Imaging; D017785:Photons; D012542:Scattering, Radiation; D013997:Time Factors; D041622:Tomography, Optical / Q000379:methods*