title: Perifolliculitis capitis abscedens et suffodiens in a caucasian: diagnostic and therapeutic challenge.
abstract: Perifolliculitis capitis abscedens et suffodiens or dissecting cellulitis of the scalp is a rare, chronic destructive folliculitis of the scalp, characterized by painful nodules, purulent drainage, sinus tracts, keloid formation and cicatricial alopecia. The cause of the disease is unknown, but it is similar in many features to hidradenitis suppurativa and acne conglobata. In our case report, the patient's dermatologic appearance included one slightly erythematous, infiltrated alopecic area with draining lesions in the right parietal part of the scalp with a few alopecic areas in other parts of the scalp. The identification of the infectious agent, repeated swabs and KOH examination/or fungal cultures and tissue sampling for histopathologic analysis were necessary to confirm the diagnosis of perifolliculitis capitis abscedens et suffodiens. The patient received systemic antibiotics (azithromycin and amoxicillin-clavulanate) and oral antimycotic therapy (fluconazole), followed by a long period of oral isotretinoin with local skin care, which led to resolution and thus inhibited the evolution to scarring and nodular stage of the disease. Thus, such combined approach could be useful for other patients with these dermatologic problems.
authors.affiliation: Department of Dermatology and Venereology, Sestre milosrdnice University Hospital Center, Zagreb, Croatia. liborija@yahoo.com
authors.forename: Liborija Lugović
authors.initials: LL
authors.lastname: Mihić
authors.forename: Davor
authors.initials: D
authors.lastname: Tomas
authors.forename: Mirna
authors.initials: M
authors.lastname: Situm
authors.forename: Iva
authors.initials: I
authors.lastname: Krolo
authors.forename: Klaudija
authors.initials: K
authors.lastname: Sebetić
authors.forename: Ines
authors.initials: I
authors.lastname: Sjerobabski-Masnec
authors.forename: Freja
authors.initials: F
authors.lastname: Barišić
mesh_terms: D001707:Biopsy, Needle; D003879:Dermatologic Agents / Q000627:therapeutic use; D018450:Disease Progression; D005499:Folliculitis / Q000188:drug therapy* / Q000473:pathology*; D005500:Follow-Up Studies; D006801:Humans; D007150:Immunohistochemistry; D015474:Isotretinoin / Q000627:therapeutic use*; D008297:Male; D012536:Scalp Dermatoses / Q000188:drug therapy* / Q000473:pathology*; D012720:Severity of Illness Index; D016896:Treatment Outcome; D044465:White People
chemical_list: D003879:Dermatologic Agents; D015474:Isotretinoin