title: Single transplanted kidneys from a 90-year-old deceased donor perform acceptably at 1 year.
abstract: Most centers are reluctant to accept expanded criteria donors above 70 to 75 years of age. We accepted kidneys from a 90-year-old male and report the 1-year outcome. The kidneys were used as single transplants and both had immediate graft function. Recipient A was a 71-year-old male, with cold ischemia time of 4 hours 49 minutes. One rejection was successfully treated with intravenous methylprednisolone. At 1 year, serum creatinine was 146 μmol/L with estimated glomerular filtration rate (eGFR) 41 mL/min. Recipient B was a 79-year-old male with known panel-reactive antibody positivity prior to transplantation. Cold ischemia time was 10 hours 4 minutes. He experienced no rejections. At 1 year serum-creatinine was 99 μmol/L with eGFR 63 mL/min. Both recipients performed a surveillance biopsy at 1 year with identical findings: interstitial fibrosis and tubular atrophy grade 1 with moderate to severe arteriolosclerosis. We conclude that both kidneys performed acceptably 1 year after engraftment. The use of old kidneys in old recipients gives them a properly functioning kidney and improves quality of life. Longer observation is needed.
authors.affiliation: Department of Specialized Medicine and Surgery, Oslo University Hospital Rikshospitalet, Oslo, Norway. karsten.midtvedt@rikshospitalet.no
authors.forename: K
authors.initials: K
authors.lastname: Midtvedt
authors.forename: T
authors.initials: T
authors.lastname: Namtvedt
authors.forename: H
authors.initials: H
authors.lastname: Scott
authors.forename: S
authors.initials: S
authors.lastname: Abedini
authors.forename: J C
authors.initials: JC
authors.lastname: Rocke
authors.forename: C
authors.initials: C
authors.lastname: Dørje
authors.forename: S
authors.initials: S
authors.lastname: Foss
authors.forename: U
authors.initials: U
authors.lastname: Christen
authors.forename: M
authors.initials: M
authors.lastname: Hagness
authors.forename: A
authors.initials: A
authors.lastname: Hartmann
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002102:Cadaver; D006801:Humans; D016030:Kidney Transplantation; D008297:Male; D014019:Tissue Donors