title: New ligands that promote cross-coupling reactions between aryl halides and unactivated arenes.
abstract: Several ligands were designed to promote transition-metal-free cross-coupling reactions of aryl halides with benzene derivatives. Among the systems probed, quinoline-1-amino-2-carboxylic acid was found to serve as an excellent catalyst for cross-coupling between aryl halides and unactivated benzene. Reactions using this inexpensive catalytic system displayed a high functional group tolerance as well as excellent chemoselectivities.
authors.affiliation: Laboratory of Regenerative Biology, Guangzhou Institute of Biomedicine and Health, CAS, Guangzhou 510530, PR China.
authors.forename: Yatao
authors.initials: Y
authors.lastname: Qiu
authors.forename: Yanghan
authors.initials: Y
authors.lastname: Liu
authors.forename: Kai
authors.initials: K
authors.lastname: Yang
authors.forename: Wenkun
authors.initials: W
authors.lastname: Hong
authors.forename: Zheng
authors.initials: Z
authors.lastname: Li
authors.forename: Zhaoyang
authors.initials: Z
authors.lastname: Wang
authors.forename: Zhiyi
authors.initials: Z
authors.lastname: Yao
authors.forename: Sheng
authors.initials: S
authors.lastname: Jiang
mesh_terms: D000634:Aminoquinolines / Q000737:chemistry*; D001555:Benzene Derivatives / Q000138:chemical synthesis* / Q000737:chemistry*; D002264:Carboxylic Acids / Q000737:chemistry*; D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D006846:Hydrocarbons, Halogenated / Q000737:chemistry*; D008024:Ligands; D015394:Molecular Structure
chemical_list: D000634:Aminoquinolines; D001555:Benzene Derivatives; D002264:Carboxylic Acids; D006846:Hydrocarbons, Halogenated; D008024:Ligands; C561511:quinoline-1-amino-2-carboxylic acid