title: [Clinical significance of glycosylated serum protein in patients with diabetic nephropathy].
abstract: OBJECTIVE
  To explore the relations between fasting blood glucose (FBG), glycosylated hemoglobin A1c (HbA1c) and glycosylated serum protein (GSP).
  
  
  METHODS
  FBG, HbA1c and GSP were measured in 303 patients with diabetic nephropathy and in 167 non-diabetic patients with comparable baseline data, and the correlations between FBG, HbA1c and GSP were analyzed.
  
  
  RESULTS
  GSP levels were significantly higher in patients with diabetic nephropathy than in the non-diabetic patients (P<0.01). In patients with diabetic nephropathy, GSP levels were found to positively correlate to FBG (r=0.606) and HbA1c (r=0.733).
  
  
  CONCLUSIONS
  Patients with diabetic nephropathy show strong correlations between FBG, HbA1c and GSP. GSP detection is convenient, stable, and practical in evaluating the average FBG over a short term, which reduces the interference by FBG fluctuations in conventional blood glucose monitoring.
authors.affiliation: Department of Endocrinology, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, China. lipeilin103@163.com
authors.forename: Pei-lin
authors.initials: PL
authors.lastname: Li
authors.forename: Rui
authors.initials: R
authors.lastname: Yang
authors.forename: Yong
authors.initials: Y
authors.lastname: Zhou
authors.forename: Hong
authors.initials: H
authors.lastname: Chen
authors.forename: De-hong
authors.initials: DH
authors.lastname: Cai
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001786:Blood Glucose / Q000032:analysis*; D001798:Blood Proteins / Q000032:analysis*; D016022:Case-Control Studies; D003924:Diabetes Mellitus, Type 2 / Q000097:blood; D003928:Diabetic Nephropathies / Q000097:blood*; D005260:Female; D006442:Glycated Hemoglobin / Q000032:analysis*; D006023:Glycoproteins / Q000032:analysis*; D006801:Humans; D008297:Male; D008875:Middle Aged; D044967:Serum / Q000378:metabolism; D000093422:Glycated Serum Proteins
chemical_list: D001786:Blood Glucose; D001798:Blood Proteins; D006442:Glycated Hemoglobin; D006023:Glycoproteins; D000093422:Glycated Serum Proteins