title: Nematocidal flavone-C-glycosides against the root-knot nematode (Meloidogyne incognita) from Arisaema erubescens tubers.
abstract: A screening of several Chinese medicinal herbs for nematicidal properties showed that Arisaema erubescens (Wall.) Schott tubers possessed significant nematicidal activity against the root-knot nematode (Meloidogyne incognita). From the ethanol extract, two nematicidal flavone-C-glycosides were isolated by bioassay-guided fractionation. The compounds were identified as schaftoside and isoschaftoside on the basis of their phytochemical and spectral data. Schaftoside and isoschaftoside possessed strong nematicidal activity against M. incognita (LC(50) = 114.66 μg/mL and 323.09 μg/mL, respectively) while the crude extract of A. erubescens exhibited nematicidal activity against the root-knot nematode with a LC(50) value of 258.11 μg/mL.
authors.affiliation: State Key Laboratory of Earth Surface Processes and Resource Ecology, Beijing Normal University, Beijing, China. dushushan@bnu.edu.cn
authors.forename: Shu Shan
authors.initials: SS
authors.lastname: Du
authors.forename: Hai Ming
authors.initials: HM
authors.lastname: Zhang
authors.forename: Chun Qi
authors.initials: CQ
authors.lastname: Bai
authors.forename: Cheng Fang
authors.initials: CF
authors.lastname: Wang
authors.forename: Qi Zhi
authors.initials: QZ
authors.lastname: Liu
authors.forename: Zhi Long
authors.initials: ZL
authors.lastname: Liu
authors.forename: Yong Yan
authors.initials: YY
authors.lastname: Wang
authors.forename: Zhi Wei
authors.initials: ZW
authors.lastname: Deng
mesh_terms: D000818:Animals; D000969:Antinematodal Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D031057:Arisaema / Q000737:chemistry*; D004305:Dose-Response Relationship, Drug; D047309:Flavones / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D009348:Nematoda / Q000187:drug effects*; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D035281:Plant Tubers / Q000737:chemistry; D014431:Tylenchoidea / Q000187:drug effects*
chemical_list: D000969:Antinematodal Agents; D047309:Flavones; D006027:Glycosides; D010936:Plant Extracts