title: Antioxidant properties of the mung bean flavonoids on alleviating heat stress.
abstract: BACKGROUND
  It is a widespread belief in Asian countries that mung bean soup (MBS) may afford a protective effect against heat stress. Lack of evidence supports MBS conferring a benefit in addition to water.
  
  
  RESULTS
  Here we show that vitexin and isovitexin are the major antioxidant components in mungbean (more than 96% of them existing in the bean seed coat), and both of them could be absorbed via gavage into rat plasma. In the plasma of rats fed with mungbean coat extract before or after exposure to heat stress, the levels of malonaldehyde and activities of lactate dehydrogenase and nitric oxide synthase were remarkably reduced; the levels of total antioxidant capacity and glutathione (a quantitative assessment of oxidative stress) were significantly enhanced.
  
  
  CONCLUSIONS
  Our results demonstrate that MBS can play additional roles to prevent heat stress injury. Characterization of the mechanisms underlying mungbean beneficial effects should help in the design of diet therapy strategies to alleviate heat stress, as well as provide reference for searching natural medicines against oxidative stress induced diseases.
authors.affiliation: College of Food Science and Nutritional Engineering, China Agricultural University, Beijing, People's Republic of China.
authors.forename: Dongdong
authors.initials: D
authors.lastname: Cao
authors.forename: He
authors.initials: H
authors.lastname: Li
authors.forename: Jianyong
authors.initials: J
authors.lastname: Yi
authors.forename: Jingjing
authors.initials: J
authors.lastname: Zhang
authors.forename: Huilian
authors.initials: H
authors.lastname: Che
authors.forename: Jiankang
authors.initials: J
authors.lastname: Cao
authors.forename: Liu
authors.initials: L
authors.lastname: Yang
authors.forename: Chunqiu
authors.initials: C
authors.lastname: Zhu
authors.forename: Weibo
authors.initials: W
authors.lastname: Jiang
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000493:pharmacokinetics / Q000494:pharmacology*; D001682:Biological Availability; D007887:Fabaceae / Q000737:chemistry*; D005419:Flavonoids / Q000493:pharmacokinetics / Q000494:pharmacology*; D018869:Heat-Shock Response / Q000187:drug effects*; D008297:Male; D018384:Oxidative Stress / Q000187:drug effects; D051381:Rats; D017208:Rats, Wistar
chemical_list: D000975:Antioxidants; D005419:Flavonoids