title: [Stromal tumors of jejunum and ileum].
abstract: Gastrointestinal stromal tumors (GIST) are the most common mesenchymal tumors of the digestive tract and 25% are in the small intestine.
  
  
  METHODS
  A retrospective study was performed on 73 patients diagnosed with intestinal cancer in three hospitals in Iasi and Galati, in a period of 12 years (1998-2009).
  
  
  RESULTS
  Stromal tumors represents 11.5% of malignant tumors of jejunum and ileum, and the average age of diagnosis was 55 years; male to female incidence was 1 : 2 (chi2 = 0.66, p > 0.05). 66.66% of patients came from urban areas (chi2 = 0.66, p > 0.05). The most frequent signs and symptoms were abdominal meteorism and abdominal pain (83%). There were no correlations between admission and discharge diagnosis. CD117 was present in all patients; CD34 was present in 66.66% of them. Survival at 2 years was 66.67% and at 5 years was 33.33%.
  
  
  CONCLUSIONS
  Preoperative diagnosis is often difficult to make, many patients come to doctors in advanced-stage and the five-year survival rate is slow. The most frequent tumor markers were CD117 and CD34.
authors.affiliation: Universităţii de Medicină si Farmacie "Gr.T. Popa" Iaşi.
authors.forename: O
authors.initials: O
authors.lastname: Ciobotaru
authors.forename: Oana-Roxana
authors.initials: OR
authors.lastname: Ciobotaru
authors.forename: Cr
authors.initials: C
authors.lastname: Dragomir
mesh_terms: D015746:Abdominal Pain / Q000453:epidemiology; D018952:Antigens, CD34 / Q000032:analysis; D014408:Biomarkers, Tumor / Q000032:analysis; D005260:Female; D005414:Flatulence / Q000453:epidemiology; D046152:Gastrointestinal Stromal Tumors / Q000737:chemistry / Q000175:diagnosis / Q000453:epidemiology* / Q000601:surgery; D006801:Humans; D007078:Ileal Neoplasms / Q000737:chemistry / Q000175:diagnosis / Q000453:epidemiology* / Q000601:surgery; D015994:Incidence; D007580:Jejunal Neoplasms / Q000737:chemistry / Q000175:diagnosis / Q000453:epidemiology* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D019009:Proto-Oncogene Proteins c-kit / Q000032:analysis; D012189:Retrospective Studies; D012307:Risk Factors; D012383:Romania / Q000453:epidemiology; D012424:Rural Population / Q000706:statistics & numerical data; D017678:Sex Distribution; D015996:Survival Rate; D014505:Urban Population / Q000706:statistics & numerical data
chemical_list: D018952:Antigens, CD34; D014408:Biomarkers, Tumor; D019009:Proto-Oncogene Proteins c-kit