title: Incidence and risk factors for reoperation of surgically treated pelvic organ prolapse.
abstract: OBJECTIVE
  The objective of our study was to estimate the incidence and to identify the risk factors for reoperation of surgically treated pelvic organ prolapse (POP).
  
  
  METHODS
  We conducted a nested case-control study among 1,811 women who underwent POP surgery from January 1988 to June 2007. Cases (n = 102) were women who required reoperation for POP following the first intervention through December 2008. Controls (n = 226) were women randomly selected from the same cohort who did not require reoperation.
  
  
  RESULTS
  The incidence of POP reoperation was 5.1 per 1,000 women-years. The cumulative incidence was 5.6%. Risk factors included preoperative prolapse in more than two vaginal compartments (adjusted OR 5.2; 95% CI 2.8-9.7), history of surgery for POP and/or urinary incontinence (adjusted OR 3.2; 95% CI 1.5-7.1), and sexual activity (adjusted OR 2.0; 95% CI 1.0-3.7).
  
  
  CONCLUSIONS
  The risk of POP reoperation is relatively low and is associated with preexisting weakness of pelvic tissues.
authors.affiliation: Urogynecology Unit, Division of Gynecology, Department of Gynecology and Obstetrics, Geneva University Hospitals, 30 boulevard de Cluse, 1211 Geneva, Switzerland. Patrick.Dallenbach@hcuge.ch
authors.forename: Patrick
authors.initials: P
authors.lastname: Dällenbach
authors.forename: Carol
authors.initials: C
authors.lastname: Jungo Nancoz
authors.forename: Isabelle
authors.initials: I
authors.lastname: Eperon
authors.forename: Jean-Bernard
authors.initials: JB
authors.lastname: Dubuisson
authors.forename: Michel
authors.initials: M
authors.lastname: Boulvain
mesh_terms: D000368:Aged; D016022:Case-Control Studies; D016001:Confidence Intervals; D005260:Female; D006801:Humans; D015994:Incidence; D008875:Middle Aged; D015999:Multivariate Analysis; D016017:Odds Ratio; D056887:Pelvic Organ Prolapse / Q000150:complications / Q000473:pathology* / Q000601:surgery*; D012086:Reoperation; D012307:Risk Factors; D012725:Sexual Behavior; D014549:Urinary Incontinence / Q000150:complications; D014621:Vagina / Q000473:pathology / Q000601:surgery