title: Target-selective fluorescent "switch-on" protein labeling by 6π-azaelectrocyclization.
abstract: Application of azaelectrocyclization and FRET techniques to lysine groups enabled the selective and sensitive detection of a target protein from a mixture, with high fluorescence contrast.
authors.affiliation: Department of Chemistry, Graduate School of Science, Osaka University, 1-1 Machikaneyama-cho, Toyonaka-shi, Osaka 560-0043, Japan. ktzenori@chem.sci.osaka-u.ac.jp
authors.forename: Katsunori
authors.initials: K
authors.lastname: Tanaka
authors.forename: Masataka
authors.initials: M
authors.lastname: Kitadani
authors.forename: Koichi
authors.initials: K
authors.lastname: Fukase
mesh_terms: D001372:Aza Compounds / Q000737:chemistry*; D003500:Cyclization; D031541:Fluorescence Resonance Energy Transfer / Q000379:methods; D005456:Fluorescent Dyes / Q000737:chemistry*; D006801:Humans; D008239:Lysine / Q000737:chemistry*; D015394:Molecular Structure; D011506:Proteins / Q000737:chemistry*; D012709:Serum Albumin / Q000737:chemistry
chemical_list: D001372:Aza Compounds; D005456:Fluorescent Dyes; D011506:Proteins; D012709:Serum Albumin; D008239:Lysine