title: [The very low birth weight and very low gestational age neonates--survival, prognosis and perspectives].
abstract: The advances in perinatal medicine during the last decades lead to a reduction in neonatal mortality rates in risk newborns and a gradual lowering of the gestational age when survival is possible to 22 weeks of gestation. In the present survey we are making a review of the studies about the survival and the prognosis in neonates with very low birth weight and gestational age (VLBW, VLGA). Infants weighting more than 1000 g and with gestational age above 28 g.w. are with a good prognosis: low neonatal mortality and morbidity rates. In newborns with gestational age between 26 and 28 g.w. the neonatal mortality rates are relatively low, however the trend of further lowering has not changed during the last 15 years; morbidity rates varies between different centers and are relatively high. The greatest medical, social and ethical dilemmas represent the newborns with gestational age less than 25 g.w. In this group with an overall high neonatal mortality (with big variations between different centers), there is a significant high morbidity rate among survived babies. These are the infants at the border of perinatal viability, the "grey zone" of the neonatology, where further discussions are going on about the activity of the obstetric management, the intensity and the amount of neonatal resuscitation.
authors.forename: L
authors.initials: L
authors.lastname: Vakrilova
authors.forename: B
authors.initials: B
authors.lastname: Stancheva
authors.forename: A
authors.initials: A
authors.lastname: Dimitrov
authors.forename: A
authors.initials: A
authors.lastname: Nikolov
mesh_terms: D006801:Humans; D007231:Infant, Newborn; D019102:Infant, Very Low Birth Weight / Q000502:physiology*; D009359:Neonatology / Q000639:trends*; D011379:Prognosis; D013534:Survival