title: Two-day bowel preparation with polyethylene glycol 3350 and bisacodyl: a new, safe, and effective regimen for colonoscopy in children.
abstract: OBJECTIVE
  To assess the safety, efficacy, and acceptance of a 2-day bowel preparation with polyethylene glycol (PEG) 3350 without electrolytes and bisacodyl for colonoscopy in children.
  
  
  METHODS
  In a prospective study, 111 children of mean age 11.9 years were given 2 g/kg of PEG and a 5-mg tablet of bisacodyl daily for 2 days before colonoscopy. Stool frequency, consistency, and adverse effects were monitored for the duration of the bowel preparation. Compliance and quality of colonic preparation were assessed on the day of the colonoscopy.
  
  
  RESULTS
  The average daily stool frequency increased from a baseline of 2, to 4* on day 1, and 6.5* on day 2 of the bowel preparation (*P < 0.001 for difference vs baseline). The colonic preparations were rated as excellent or good in 92% and 93% of the patients in the right and left colon, respectively. Adverse effects were mild nausea (19%), abdominal pain (11%), and vomiting (4%). The compliance was rated as excellent in 95% of the patients.
  
  
  CONCLUSIONS
  A 2-day bowel preparation with PEG and bisacodyl is safe, effective, and well accepted for colonoscopy in children without any major adverse effects.
authors.affiliation: Division of Gastroenterology, Department of Pediatrics, Yale University, New Haven, CT 06520, USA.
authors.forename: Uma P
authors.initials: UP
authors.lastname: Phatak
authors.forename: Susanne
authors.initials: S
authors.lastname: Johnson
authors.forename: Sohail Z
authors.initials: SZ
authors.lastname: Husain
authors.forename: Dinesh S
authors.initials: DS
authors.lastname: Pashankar
mesh_terms: D000293:Adolescent; D000328:Adult; D001726:Bisacodyl / Q000008:administration & dosage* / Q000009:adverse effects; D002400:Cathartics / Q000008:administration & dosage* / Q000009:adverse effects; D002648:Child; D002675:Child, Preschool; D003113:Colonoscopy; D005260:Female; D006801:Humans; D008297:Male; D055118:Medication Adherence; D011092:Polyethylene Glycols / Q000008:administration & dosage* / Q000009:adverse effects; D011300:Preoperative Care; D013607:Tablets; D055815:Young Adult
chemical_list: D002400:Cathartics; D013607:Tablets; D001726:Bisacodyl; D011092:Polyethylene Glycols