title: Ganglioneuroma in the small intestine of a juvenile pig.
abstract: A mass was located in the small intestine of a slaughtered 6-month-old male Landrace-cross pig that had no clinical abnormalities. This egg-shaped well-circumscribed mass was situated in the submucosal and muscular tissue layers and protruded into the lumen. Histopathologically, the tumor comprised discrete or aggregated ganglion and schwannian cells in neuropil-like tissue. Some ganglion cells contained Nissl substance in their cytoplasm. The ganglion cells stained positive for neuron-specific enolase, class III β-tubulin, neurofilament, and synaptophysin; the schwannian cells stained positive for vimentin, S-100 protein, and glial fibrillary acidic protein. The tumor was diagnosed as a ganglioneuroma in accordance with these findings. Here, we have reported detailed immunohistochemical findings in addition to the histopathological features of a swine ganglioneuroma.
authors.affiliation: Laboratory of Veterinary Pathology, Department of Veterinary Medicine, Faculty of Applied Biological Sciences, Gifu University, 1–1 Yanagido, Gifu 501–1193, Japan.
authors.forename: Mami
authors.initials: M
authors.lastname: Murakami
authors.forename: Hiroki
authors.initials: H
authors.lastname: Sakai
authors.forename: Kenji
authors.initials: K
authors.lastname: Mizutani
authors.forename: Tokuma
authors.initials: T
authors.lastname: Yanai
mesh_terms: D000818:Animals; D014408:Biomarkers, Tumor / Q000378:metabolism; D005729:Ganglioneuroma / Q000378:metabolism / Q000473:pathology / Q000662:veterinary*; D007414:Intestinal Neoplasms / Q000378:metabolism / Q000473:pathology / Q000662:veterinary*; D007421:Intestine, Small; D008297:Male; D013552:Swine; D013553:Swine Diseases / Q000378:metabolism / Q000473:pathology*
chemical_list: D014408:Biomarkers, Tumor