title: [Clinical aspects of intestinal dysbacteriosis].
abstract: The article presents data of domestic and foreign literature on intestinal dysbacteriosis. It is evident that intestinal dysbiosis always secondary and its correction should take into account the reasons that caused the violation of the microbial composition of the intestinal flora and the clinical manifestations of this syndrome. The characteristic of the normal intestinal microflora and its significance for the human body. It was emphasized that the resident microflora influences the development of the immune response of the intestinal mucosa, epithelial differentiation and proliferation, motility, is actively involved in the digestion and absorption, and synthesis of vitamins and bioactive substances. It was described factors leading to violation of the microbial composition of intestine, as well as methods of diagnosis and treatment of dysbiosis. Therapeutic measures for dysbiosis conducted according to the nature and severity of underlying disease and were in compliance with dietary recommendations and the use of drugs, normalizing the intestinal microflora. In order to remove from the intestinal lumen conditionally pathogenic microorganisms and toxins using different chelators. One of the members of this group of drugs is Laktofiltrum. Laktofiltrum drug effective in treating patients with bowel diseases, accompanied by dysbiosis, as a monotherapy and in combination with other drugs.
authors.forename: E A
authors.initials: EA
authors.lastname: Sabel'nikova
mesh_terms: D016061:Enterosorption; D006801:Humans; D007410:Intestinal Diseases / Q000175:diagnosis* / Q000382:microbiology / Q000628:therapy; D007413:Intestinal Mucosa / Q000382:microbiology*