title: [Application of transumbilical antibacterial therapy in patients with acute purulent cholangitis].
abstract: In 2004 - 2010 yrs 75 patients were treated for an acute purulent cholangitis (APCH). In 42 (41.2%) patients (the main group), suffering an acute cholecystitis, choledocholithiasis, duodenal papilla magna (DPM) stenosis, obturation jaundice and APCH, transumbilical introduction of antibiotics (TUIA) and operative intervention were performed; in 33 (33.3%) patients (control group) antibiotics were administered intravenously. In APCH inflammatory reaction have disappeared faster while TUIA application. TUIA and endobiliary sanation application have secured achievement of high antibiotics concentration in biliary ducts, as well as an effective impact on microflora, prophilacting cholangiogenous infection generalization. TUIA owes significant advantages in comparison with conventional methods of antibacterial therapy.
authors.forename: O A
authors.initials: OA
authors.lastname: Shkurupiĭ
mesh_terms: D000208:Acute Disease; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000008:administration & dosage* / Q000627:therapeutic use; D002761:Cholangitis / Q000097:blood / Q000188:drug therapy* / Q000473:pathology; D005334:Fever / Q000517:prevention & control; D006801:Humans; D007262:Infusions, Intravenous; D007275:Injections, Intravenous; D007958:Leukocyte Count; D008875:Middle Aged; D013492:Suppuration; D013997:Time Factors; D016896:Treatment Outcome; D014471:Umbilical Veins
chemical_list: D000900:Anti-Bacterial Agents