title: Helicobacter pylori has no influence on distal gastric cancer survival.
abstract: BACKGROUND
  There is some evidence that Helicobacter pylori correlates with distal gastric cancer genesis. However, few studies analyzed the survival related to H. pylori infection.
  
  
  OBJECTIVE
  To correlate gastric cancer survival and H. pylori infection.
  
  
  METHODS
  Sixty-eight patients with distal gastric cancer that underwent subtotal gastrectomy were studied. Minimal follow-up was 1 month. H. pylori infection was confirmed by biopsy.
  
  
  RESULTS
  Thirty-four patients (19 males (55.9%), mean age 60.9 ± 14.03, range 33-82 years) were H. pylori positive. Thirty-four patients (16 males (47.1%), mean age 57.9 ± 13.97, range 27-85 years) were H. pylori negative. Groups were comparable in regards to age (P = 0.4), gender (P = 0.5), stage [T (P = 0.2), N (P = 0.6) and M (P = 0.9)]. Survival was not different when groups were compared [P = 0.1616 (hazard ratio 0.6834, 95% CI 0.4009 to 1.1647)].
  
  
  CONCLUSIONS
  H. pylori infection does not affect distal gastric cancer survival.
authors.affiliation: Department of Surgery, Escola Paulista de Medicina, Federal University of São Paulo, São Paulo, Brazil.
authors.forename: Renata S
authors.initials: RS
authors.lastname: Santos
authors.forename: José E V
authors.initials: JE
authors.lastname: Lourenço
authors.forename: Fernando Augusto Mardiros
authors.initials: FA
authors.lastname: Herbella
authors.forename: Jose Carlos
authors.initials: JC
authors.lastname: Del Grande
authors.forename: Marco G
authors.initials: MG
authors.lastname: Patti
mesh_terms: D000230:Adenocarcinoma / Q000382:microbiology* / Q000401:mortality*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D016481:Helicobacter Infections / Q000150:complications* / Q000401:mortality*; D016480:Helicobacter pylori; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011379:Prognosis; D012189:Retrospective Studies; D013274:Stomach Neoplasms / Q000382:microbiology* / Q000401:mortality*; D016019:Survival Analysis