title: Practical use of GenoType® HelicoDR, a molecular test for Helicobacter pylori detection and susceptibility testing.
abstract: Compared to culture-based method, the sensitivity, specificity, positive, and negative predictive values of the GenoType(®) HelicoDR for detecting Helicobacter pylori resistance were, respectively, 100, 86.2, 89.7%, and 100% to clarithromycin as well as 82.6, 95.1, 90.5%, and 90.7% to fluoroquinolones. This molecular assay detected a mixture of genotypes and could successfully analyze biopsies without transport/storage limitations.
authors.affiliation: Section of Microbiology, Clinical Biology Department, Brugmann University Hospital, Université Libre de Bruxelles, Brussels, Belgium. yvette.miendje@chu-brugmann.be
authors.forename: Véronique Yvette
authors.initials: VY
authors.lastname: Miendje Deyi
authors.forename: Alain
authors.initials: A
authors.lastname: Burette
authors.forename: Zahra
authors.initials: Z
authors.lastname: Bentatou
authors.forename: Younes
authors.initials: Y
authors.lastname: Maaroufi
authors.forename: Patrick
authors.initials: P
authors.lastname: Bontems
authors.forename: Philippe
authors.initials: P
authors.lastname: Lepage
authors.forename: Marijke
authors.initials: M
authors.lastname: Reynders
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001431:Bacteriological Techniques / Q000379:methods*; D002648:Child; D002675:Child, Preschool; D005260:Female; D005838:Genotype; D016481:Helicobacter Infections / Q000175:diagnosis* / Q000382:microbiology*; D016480:Helicobacter pylori / Q000187:drug effects* / Q000235:genetics / Q000302:isolation & purification*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D012680:Sensitivity and Specificity; D055815:Young Adult
chemical_list: D000900:Anti-Bacterial Agents