title: Capecitabine (oral 5-fluorouracil pro-drug) treatment for colorectal carcinoma causing ischaemic chest pain.
abstract: We present a case of cardiac ischaemia associated with capecitabine chemotherapy. An elderly female receiving capecitabine chemotherapy developed acute onset severe anterior chest pain associated with ischaemic changes on ECG. The pain and ECG changes failed to respond to thrombolysis and she proceeded to coronary angiogram and stenting of a thrombosed right coronary vessel. She inadvertently recommenced her capecitabine with a further episode of chest pain. On cessation of capecitabine she had no further episodes of chest pain.
authors.affiliation: University of Edinburgh, Clinical Pharmacology, Queen's Medical Research Institute, 47 Little France Crescent, Edinburgh EH16 4TJ, UK.
authors.forename: Trevor Aidan
authors.initials: TA
authors.lastname: McGoldrick
authors.forename: Duncan
authors.initials: D
authors.lastname: Jodrell
authors.forename: Sally
authors.initials: S
authors.lastname: Clive