title: Split liver transplantation.
abstract: We analyzed the results of 55 patients who underwent split liver transplantation at our center between September 1996 and December 2008, 30 adults (54.5%) and 25 children (45.5%). Median follow-up was 12 years. Overall patient survival was 71%, adult 70% and pediatric 72%. Mean patient survival was 61.58 months, and mean graft survival was 44.35 months. Pediatric survival and pediatric graft survival after 1 and 5 years were 84% and 72% and 72% and 52.4%, respectively. Adult survival and adult graft survival after 1 and 5 years were 75% and 66.2% and 60.7% and 51.5%, respectively. Twelve patients required retransplantation, 6 for primary nonfunction, 3 for chronic rejection, and 3 for vascular complications. Blood groups of the recipient patients were: 34 O, 14 A, 7 B, and 0 AB. The use of split liver for adult and pediatric populations allows us to expand the cadaveric donor pool and has the potential to significantly reduce waiting list mortality, especially for certain blood groups.
authors.affiliation: Division of Transplantation, Department of Surgery, University of Miami School of Medicine, Miami, Florida 33136, USA. eviatar.nesher@gmail.com
authors.forename: E
authors.initials: E
authors.lastname: Nesher
authors.forename: E
authors.initials: E
authors.lastname: Island
authors.forename: P
authors.initials: P
authors.lastname: Tryphonopoulos
authors.forename: J
authors.initials: J
authors.lastname: Moon
authors.forename: S
authors.initials: S
authors.lastname: Nishida
authors.forename: G
authors.initials: G
authors.lastname: Selvaggi
authors.forename: A
authors.initials: A
authors.lastname: Tekin
authors.forename: D M
authors.initials: DM
authors.lastname: Levi
authors.forename: A
authors.initials: A
authors.lastname: Tzakis
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D005260:Female; D006085:Graft Survival; D006801:Humans; D016031:Liver Transplantation / Q000379:methods*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D015996:Survival Rate; D055815:Young Adult