title: Effect of early orthodontic force on periodontal healing after autotransplantation of permanent incisors in beagle dogs.
abstract: BACKGROUND
  Masticatory stimulation during the healing period may promote periodontal ligament healing. The aim of the present study is to investigate the effect of orthodontic force on the periodontal healing of autotransplanted teeth.
  
  
  METHODS
  A total of 30 teeth from four dogs were endodontically treated to prevent subsequent inflammatory root resorption. The teeth were atraumatically extracted and autotransplanted to the other side of the same jaw. A continuous 50-g orthodontic force was applied during the first, second, and fourth weeks after autotransplantation. After 8 weeks, the animals were sacrificed using vital perfusion fixation, and the teeth were histologically prepared and evaluated following the Andreasen method.
  
  
  RESULTS
  The application of force in the first, second, and fourth weeks after autotransplantation resulted in a lower occurrence of ankylosis. The first- and second-week loading groups differed significantly from the control group (P <0.05); however, significantly more resorption and less complete healing were observed in the first-week loading group than in the other groups (P <0.05).
  
  
  CONCLUSIONS
  The results of this study demonstrate that orthodontic force promotes periodontal ligament healing and that early force loading may prevent dentoalveolar ankylosis; however, a period of rest of ≥2 weeks is recommended for the autotransplants before loading.
authors.affiliation: Department of Orthodontics, School of Stomotology, Capital Medical University, Beijing, China.
authors.forename: Yun
authors.initials: Y
authors.lastname: Yang
authors.forename: Yuxing
authors.initials: Y
authors.lastname: Bai
authors.forename: Song
authors.initials: S
authors.lastname: Li
authors.forename: Jiangning
authors.initials: J
authors.lastname: Li
authors.forename: Weimin
authors.initials: W
authors.lastname: Gao
authors.forename: Nan
authors.initials: N
authors.lastname: Ru
mesh_terms: D000818:Animals; D003799:Dental Stress Analysis; D004285:Dogs; D010513:Periodontal Ligament / Q000502:physiology*; D012390:Root Canal Therapy; D012391:Root Resorption / Q000209:etiology; D013997:Time Factors; D014070:Tooth / Q000637:transplantation*; D020254:Tooth Ankylosis / Q000517:prevention & control; D014087:Tooth Movement Techniques / Q000009:adverse effects; D014182:Transplantation, Autologous / Q000009:adverse effects; D014945:Wound Healing