title: The value of 18F-FDG-PET/CT imaging for sinonasal malignant melanoma.
abstract: The aim this study was to evaluate imaging findings using position emission tomography (PET) in combination with computed tomography (CT) and 18F-fluorodeoxyglucose ((18)F-FDG) in sinonasal malignant melanoma (SNMM) of the head and neck in a retrospective analysis of a consecutive cohort of patients. (18)F-FDG-PET/CT examinations were performed for initial staging and compared with CT or magnetic resonance tomography (MRI), and (18)F-FDG-PET alone. Medical records were reviewed retrospectively with regard to the location and the size of the tumor. Furthermore, locoregional and distant metastases with a consecutive change in therapy detected by (18)F-FDG-PET/CT were assessed. Ten patients suffering from sinonasal malignant melanoma were staged and followed by (18)F-FDG-PET/CT imaging. A total of 34 examinations were obtained. (18)F-FDG-PET/CT depicted all primary tumors adequately. Aside from one cerebral metastasis all regional and distant metastases were truly identified by using this method. In summary, if available, (18)F-FDG-PET/CT is a valuable imaging modality for staging and re-staging sinonasal malignant melanoma to evaluate expansion of the primary tumor, locoregional disease, and distant metastases.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, University Hospital Zurich, Frauenklinikstrasse 24, 8091 Zurich, Switzerland. stephan.haerle@usz.ch
authors.forename: S K
authors.initials: SK
authors.lastname: Haerle
authors.forename: M B
authors.initials: MB
authors.lastname: Soyka
authors.forename: D R
authors.initials: DR
authors.lastname: Fischer
authors.forename: K
authors.initials: K
authors.lastname: Murer
authors.forename: K
authors.initials: K
authors.lastname: Strobel
authors.forename: G F
authors.initials: GF
authors.lastname: Huber
authors.forename: D
authors.initials: D
authors.lastname: Holzmann
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005005:Ethmoid Sinus; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008297:Male; D008444:Maxillary Sinus Neoplasms / Q000000981:diagnostic imaging; D008545:Melanoma / Q000000981:diagnostic imaging*; D008875:Middle Aged; D064847:Multimodal Imaging; D009296:Nasal Cavity; D009669:Nose Neoplasms / Q000000981:diagnostic imaging*; D010255:Paranasal Sinus Neoplasms / Q000000981:diagnostic imaging*; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals; D014057:Tomography, X-Ray Computed
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18