title: Neurodevelopmental outcomes in very low-birth-weight infants in Korea: 1998-2007 vs 1989-1997.
abstract: The authors reviewed the medical records of very low-birth-weight infants admitted from 1998 to 2007 and compared neurodevelopmental outcomes with their previously reported data from 1989 to 1997. The recent group included 824 infants, and the previous group included 471 infants. Neurodevelopmental outcomes were classified into cerebral palsy and non-cerebral palsy neurodevelopmental impairment. In the recent group, the survival rate was significantly higher (79.4% vs 66.2%), the rate of cerebral palsy was lower (7.9% vs 10.5%), and the rate of non-cerebral palsy neurodevelopmental impairment was higher (6.0% vs 4.5%) but not significant. The survival rate increased significantly over time, but there was no significant change in neurodevelopmental outcomes over time. Multivariate analysis indicated that abnormal neurosonographic findings, using assisted ventilation, vaginal delivery, and abnormal brainstem auditory evoked potential, were associated with increased risk for cerebral palsy.
authors.affiliation: Department of Rehabilitation, Incheon St Mary's Hospital, The Catholic University of Korea, Incheon, Korea.
authors.forename: Dae-Hyun
authors.initials: DH
authors.lastname: Jang
authors.forename: In Young
authors.initials: IY
authors.lastname: Sung
authors.forename: Jae Yong
authors.initials: JY
authors.lastname: Jeon
authors.forename: Hye Jin
authors.initials: HJ
authors.lastname: Moon
authors.forename: Ki-Soo
authors.initials: KS
authors.lastname: Kim
authors.forename: Ellen Ai-Rhan
authors.initials: EA
authors.lastname: Kim
authors.forename: Byong Sop
authors.initials: BS
authors.lastname: Lee
mesh_terms: D002547:Cerebral Palsy / Q000453:epidemiology / Q000209:etiology; D002657:Child Development; D002658:Developmental Disabilities / Q000453:epidemiology* / Q000209:etiology / Q000401:mortality; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D019102:Infant, Very Low Birth Weight; D008297:Male; D056910:Republic of Korea / Q000453:epidemiology; D016019:Survival Analysis; D015996:Survival Rate; D013997:Time Factors