title: [Laparoscopic ovarian drilling and biopsy in women with polycystic ovaries (PCOS) and infertility].
abstract: OBJECTIVE
  To evaluate ovarian reserve according to results of biopsy of ovaries during laparoscopy. To investigate connections between hystologic results, drilling of ovaries and pregnancies.
  
  
  METHODS
  We investigate prospectively 74 patients with polycystic ovaries (PCOS) and infertility. Operative laparoscopy have be done in 2006, 2008 and 2009 year in University Hospital "Maichin Dom" Sofia, Bulgaria. All patients had ovarian drilling and biopsy.
  
  
  RESULTS
  Microscopic findings from biopsy of ovary in 74 women with PCOS were divided in 4 groups. In this investigation from 74 women with operative laparoscopy 33 patients (44.5%) were pregnant.
  
  
  CONCLUSIONS
  The results of biopsy and registered pregnancies in PCOS patients is very difficult to analyse. Laparoscopic ovarian drilling and biopsy affect ovarian tissue. The ovary probably change own characteristics--ovarian metabolism and physiology are restored and this changes our clinical prognosis for a future pregnancies.
authors.forename: M
authors.initials: M
authors.lastname: Punevska
authors.forename: E
authors.initials: E
authors.lastname: Filipov
authors.forename: K
authors.initials: K
authors.lastname: Mainhart
authors.forename: R
authors.initials: R
authors.lastname: Zhivkova
mesh_terms: D000328:Adult; D001706:Biopsy; D002031:Bulgaria; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000473:pathology* / Q000601:surgery; D010535:Laparoscopy; D010053:Ovary / Q000473:pathology* / Q000601:surgery; D011085:Polycystic Ovary Syndrome / Q000473:pathology* / Q000601:surgery; D011247:Pregnancy; D011446:Prospective Studies; D055815:Young Adult