title: [Predictive value of test with procalcitonin in diagnostics of endogenous intoxication severity in extended purulent peritonitis].
abstract: Diagnostic significance of the test with procalcitonin (PCT) for estimation of the patients state severity in extended purulent peritonitis (EPP) and prognostication of hospital lethality were studied up. For the comparison making the state severity was estimated in the patients in accordance to SOFA scale, basing on the clinical and laboratory data analysis, the leukocyte index of intoxication (LII) and hematological index of intoxication (HII) on the second postoperative day. In all the patients the symptoms, corresponding to criteria of endogenous abdominal intoxication, were revealed. The EPP course severity was estimated in accordance with the hospital lethality index. There was established, that specific test with PCT owes high prognostic validity in diagnosis of endogenous intoxication severity, it may be applied as a secure diagnostic marker for the state severity estimation and hospital lethality prognostication in patients, suffering EPP. Otherwise, nonspecific markers of endotoxicosis, including LII and HII, lack informativity, owes low prognostic validity and do not permit to estimate of such a patients state severity.
authors.forename: A Ia
authors.initials: AIa
authors.lastname: Pavliak
mesh_terms: D000328:Adult; D000368:Aged; D015415:Biomarkers / Q000097:blood; D002116:Calcitonin / Q000097:blood*; D015740:Calcitonin Gene-Related Peptide; D003627:Data Interpretation, Statistical; D019446:Endotoxemia / Q000097:blood* / Q000401:mortality / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010538:Peritonitis / Q000097:blood* / Q000401:mortality / Q000601:surgery; D011237:Predictive Value of Tests; D011379:Prognosis; D011498:Protein Precursors / Q000097:blood*; D012372:ROC Curve; D012720:Severity of Illness Index; D013492:Suppuration
chemical_list: D015415:Biomarkers; C000606589:CALCA protein, human; D011498:Protein Precursors; D002116:Calcitonin; D015740:Calcitonin Gene-Related Peptide