title: [Cancer immunotherapy by utilizing dedritic cells derived from pluripotent stem cells].
abstract: It was recently revealed that ES-cell like pluripotent stem cells, designated as iPS cells, can be generated from somatic cells. iPS cells could be used as not only a source of regeneration medicine, but also a source of cell vaccine. Pluripotent stem cells are characterized by pluripotency and infinite propagation capacity. Non-virus-mediated methods for gene transfer have been established. Genetic modification of pluripotent stem cells and subsequent in vitro differentiation to dendritic cells would be an attractive strategy. Here we describe the previous studies about cancer immunotherapy by utilizing dendritic cells derived from pluripotent stem cells.
authors: Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, Japan.
authors: Satoshi
authors: S
authors: Fukushima
authors: Hironobu
authors: H
authors: Ihn
authors: Yasuharu
authors: Y
authors: Nishimura
authors: Satoru
authors: S
authors: Senju
mesh_terms: D000818:Animals; D002454:Cell Differentiation; D003713:Dendritic Cells / Q000166:cytology; D053595:Embryonic Stem Cells / Q000166:cytology; D018014:Gene Transfer Techniques; D006801:Humans; D007167:Immunotherapy / Q000379:methods*; D057026:Induced Pluripotent Stem Cells / Q000166:cytology; D008545:Melanoma / Q000628:therapy; D051379:Mice; D009369:Neoplasms / Q000628:therapy*; D039904:Pluripotent Stem Cells / Q000166:cytology