title: Orthogonally dual-clickable Janus nanoparticles via a cyclic templating strategy.
abstract: Synthetic asymmetrical systems, Janus particles and patchy particles, are capable of undergoing hierarchical assembly processes that mimic those of Nature, to serve as switchable devices, optical probes, phase-transfer catalysts, and multifunctional drug carriers, each of which benefits from opposing surface patterns that behave differently. Production of nanometer-sized Janus particles that are equipped with efficient chemistries remains a challenge. A robust Janus-faced polymer nanoparticle framework that presents two orthogonally click-reactive surface chemistries has been generated by a recyclable strategy that involves reactive functional group transfer by templating against gold nanoparticle substrates. This anisotropic functionalization approach is compatible with a wide range of soft materials, providing Janus nanoparticles for the construction of dual-functionalized devices by accurately controlling chemical functionality at the nanoscopic level.
authors: Department of Chemistry, Texas A&M University, College Station, Texas 77842, USA.
authors: Shiyi
authors: S
authors: Zhang
authors: Zhou
authors: Z
authors: Li
authors: Sandani
authors: S
authors: Samarajeewa
authors: Guorong
authors: G
authors: Sun
authors: Chao
authors: C
authors: Yang
authors: Karen L
authors: KL
authors: Wooley
mesh_terms: D000480:Alkynes / Q000737:chemistry; D016880:Anisotropy; D001386:Azides / Q000737:chemistry; D057930:Click Chemistry; D006046:Gold / Q000737:chemistry; D053758:Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D036103:Nanotechnology / Q000379:methods*; D013499:Surface Properties
chemical_list: D000480:Alkynes; D001386:Azides; D006046:Gold