title: A merkel cell carcinoma of the lacrimal gland.
abstract: Merkel cell carcinoma is a rare neuroendocrine carcinoma that most often arises in sun-exposed skin. Primary Merkel cell carcinoma of the lacrimal gland is exceedingly rare, with only one prior case reported in the literature. The authors present a 49-year-old woman with a 6-month history of painless swelling of the left upper eyelid. MRI showed a lacrimal gland mass. Surgical excision was performed, and histologic evaluation revealed a Merkel cell carcinoma. Virology testing was positive for Merkel cell polyomavirus. The patient was treated with local radiation following surgical excision. She has had no recurrence after 1 year of follow up.
authors: Department of Ophthalmology,California Pacific Medical Center, San Francisco, CA 94115, USA. adamgess@gmail.com
authors: Adam J
authors: AJ
authors: Gess
authors: Rona Z
authors: RZ
authors: Silkiss
mesh_terms: D015266:Carcinoma, Merkel Cell / Q000175:diagnosis*; D005142:Eyelid Neoplasms / Q000175:diagnosis*; D005260:Female; D006801:Humans; D007765:Lacrimal Apparatus; D059965:Merkel cell polyomavirus / Q000302:isolation & purification; D008875:Middle Aged; D027601:Polyomavirus Infections / Q000175:diagnosis*; D035583:Rare Diseases / Q000175:diagnosis; D012878:Skin Neoplasms / Q000175:diagnosis*; D014412:Tumor Virus Infections / Q000175:diagnosis*