title: Phosphorescent sensor for robust quantification of copper(II) ion.
abstract: A phosphorescent sensor based on a multichromophoric iridium(III) complex was synthesized and characterized. The construct exhibits concomitant changes in its phosphorescence intensity ratio and phosphorescence lifetime in response to copper(II) ion. The sensor, which is reversible and selective, is able to quantify copper(II) ions in aqueous media, and it detects intracellular copper ratiometrically.
authors: Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA. odds2@mit.edu
authors: Youngmin
authors: Y
authors: You
authors: Yejee
authors: Y
authors: Han
authors: Yong-Min
authors: YM
authors: Lee
authors: Soo Young
authors: SY
authors: Park
authors: Wonwoo
authors: W
authors: Nam
authors: Stephen J
authors: SJ
authors: Lippard
mesh_terms: D003300:Copper / Q000032:analysis*; D005456:Fluorescent Dyes / Q000138:chemical synthesis / Q000737:chemistry*; D006367:HeLa Cells; D006801:Humans; D007477:Ions / Q000032:analysis; D007495:Iridium / Q000737:chemistry*; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000138:chemical synthesis / Q000737:chemistry*
chemical_list: D005456:Fluorescent Dyes; D007477:Ions; D009942:Organometallic Compounds; D007495:Iridium; D003300:Copper