title: Liposomal amphotericin B-induced hypotension leading to ST segment elevated myocardial infarction.
abstract: We hereby report a short case of 71-year-old gentleman who developed ST segment elevation myocardial infarction shortly after starting the infusion of liposomal amphotericin B for disseminated histoplasmosis. We also discuss the novel pathogenesis of specific liposomal component of amphotericin B that contributed to the acute cardiopulmonary compromise in our patient leading to subsequent myocardial infarction.
authors: Department of Internal Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73190, USA. harsh-golwala@ouhsc.edu
authors: Harsh
authors: H
authors: Golwala
authors: Nishit
authors: N
authors: Patel
authors: Soni
authors: S
authors: Zacharias
authors: Pedro
authors: P
authors: Lozano
mesh_terms: D000368:Aged; D000666:Amphotericin B / Q000009:adverse effects* / Q000627:therapeutic use; D000935:Antifungal Agents / Q000009:adverse effects* / Q000627:therapeutic use; D006660:Histoplasmosis / Q000188:drug therapy; D006801:Humans; D007022:Hypotension / Q000139:chemically induced*; D008297:Male; D009203:Myocardial Infarction / Q000139:chemically induced*
chemical_list: D000935:Antifungal Agents; C068538:liposomal amphotericin B; D000666:Amphotericin B