title: Recurrent pyogenic meningitis in a 17-year-old: a delayed presentation of X-linked agammaglobulinemia with growth hormone deficiency.
abstract: We report an adolescent male with X-linked agammaglobulinemia (XLA) and recurrent episodes of pyogenic meningitis. The workup for proportionate short stature revealed isolated growth hormone deficiency. This patient highlights the delayed presentation of the XLA variant and the need to consider primary immunodeficiency in patients with recurrent serious infections, irrespective of age.
authors: Department of General Medicine, Lokmanya Tilak Municipal Medical College and General Hospital, Sion, Mumbai, India. girishsabnis@live.in
authors: Girish R
authors: GR
authors: Sabnis
authors: Niteen D
authors: ND
authors: Karnik
authors: Swati A
authors: SA
authors: Chavan
authors: Deepa S
authors: DS
authors: Korivi
mesh_terms: D000293:Adolescent; D000361:Agammaglobulinemia / Q000150:complications* / Q000235:genetics*; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001797:Blood Protein Electrophoresis; D001827:Body Height; D040181:Genetic Diseases, X-Linked / Q000150:complications* / Q000235:genetics*; D019382:Human Growth Hormone / Q000172:deficiency*; D006801:Humans; D018655:Lymphocyte Count; D008297:Male; D008581:Meningitis / Q000209:etiology / Q000276:immunology / Q000473:pathology*; D012008:Recurrence; D014839:Vomiting / Q000150:complications
chemical_list: D000900:Anti-Bacterial Agents; D019382:Human Growth Hormone