title: [A case of pneumatosis cystoides intestinalis induced by steroid pulse therapy for severe acute hepatitis B].
abstract: A 26-year-old Japanese woman was admitted to the hospital because of fever and general fatigue. A diagnosis of acute hepatitis B was given because of high levels of transaminase and positivity for HBs-Ag, HBe-Ag and HBc-IgM. On the 2nd day progression to fulminant hepatitis was suspected, and steroid pulse therapy, cyclosporin, entecavir, and interferon-β were started. Her laboratory data improved until transaminase showed an increase on 18th day, and steroid was once again administered. Abdominal CT scan and plain abdominal X-ray showed pneumatosis cystoides intestinalis (PCI) mainly along the ascending colon without any symptoms. After discontinuation of steroid therapy, abnormal gas gradually disappeared. This is a very rare case of PCI, which may have been caused by short-term steroid pulse therapy.
authors: Division of Gastroenterology, Kitasato University Kitasato Institute Hospital.
authors: Hiroshi
authors: H
authors: Ohara
authors: Yukako
authors: Y
authors: Kato
authors: Masaru
authors: M
authors: Nakano
authors: Yasuhisa
authors: Y
authors: Ishii
authors: Hiroshi
authors: H
authors: Serizawa
authors: Noriaki
authors: N
authors: Watanabe
authors: Kanji
authors: K
authors: Wakabayashi
authors: Satoshi
authors: S
authors: Tsunematsu
authors: Naoki
authors: N
authors: Kumagai
authors: Kanji
authors: K
authors: Tsuchimoto
authors: Toshifumi
authors: T
authors: Hibi
mesh_terms: D000208:Acute Disease; D000328:Adult; D005260:Female; D006509:Hepatitis B / Q000188:drug therapy*; D006801:Humans; D008775:Methylprednisolone / Q000008:administration & dosage* / Q000009:adverse effects*; D011006:Pneumatosis Cystoides Intestinalis / Q000139:chemically induced*; D020551:Pulse Therapy, Drug
chemical_list: D008775:Methylprednisolone