title: Ewing's sarcoma of the masseter muscle.
abstract: OBJECTIVE
  To present a case of extraskeletal Ewing's sarcoma originating in the masseter muscle, and to review the diagnosis and management of these rare tumours.
  
  
  METHODS
  Case report and literature review.
  
  
  RESULTS
  We report a patient with Ewing's sarcoma of the masseter muscle with mandibular invasion. She was treated with induction chemotherapy, salvage surgery and free flap reconstruction.
  
  
  CONCLUSIONS
  This case highlights the management of these rare tumours. Aggressive multi-modal treatment, including multi-agent chemotherapy, surgical resection and irradiation, appears to offer the best prognosis. Contemporary reconstructive techniques can restore function and form in cases with challenging defects.
authors: Schulich School of Medicine, University of Western Ontario, London, Canada.
authors: H A
authors: HA
authors: Osborn
authors: B
authors: B
authors: Wehrli
authors: J H
authors: JH
authors: Franklin
authors: K
authors: K
authors: Fung
mesh_terms: D000328:Adult; D044963:Biopsy, Fine-Needle; D003131:Combined Modality Therapy; D018572:Disease-Free Survival; D004307:Dose-Response Relationship, Radiation; D005260:Female; D006258:Head and Neck Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D006801:Humans; D007150:Immunohistochemistry; D017404:In Situ Hybridization, Fluorescence; D008334:Mandible / Q000473:pathology / Q000601:surgery; D008406:Masseter Muscle / Q000473:pathology*; D019042:Muscle Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D035583:Rare Diseases; D019651:Plastic Surgery Procedures / Q000379:methods; D012512:Sarcoma, Ewing / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D013524:Surgical Flaps; D015996:Survival Rate; D055815:Young Adult