title: Risk factors for prolonged shedding of 2009 H1N1 influenza virus.
abstract: This retrospective study was conducted to estimate the shedding of 2009 H1N1 virus and the risk analysis by review of medical charts, laboratory and radiological findings of all inpatients with confirmed pandemic influenza A (H1N1) at a provincial pediatric hospital. A total of 41 cases attending the inpatient department between 15 November, 2009 to 14 December, 2009 were included. Prolonged and discontinuous shedding of 2009 H1N1 virus (median, 10 days; range, 2 to 24 days) were detected by real-time RT-PCR. The interval from onset of symptom to the start of oseltamivir therapy was an independent risk factor for prolonged virus shedding.
authors: Division of Infection Disease, Zhejiang Key Laboratory for Neonatal Disease, Childrens Hospital of Zhejiang University Medical College, Hangzhou 310003, China.
authors: Yinghu
authors: Y
authors: Chen
authors: Huiju
authors: H
authors: Qiao
authors: Chen Mei
authors: CM
authors: Zhang
authors: Meiqin
authors: M
authors: Tong
authors: Shiqiang
authors: S
authors: Shang
mesh_terms: D000998:Antiviral Agents / Q000627:therapeutic use; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D053118:Influenza A Virus, H1N1 Subtype / Q000502:physiology*; D007251:Influenza, Human / Q000188:drug therapy / Q000821:virology*; D053139:Oseltamivir / Q000627:therapeutic use; D060888:Real-Time Polymerase Chain Reaction; D012189:Retrospective Studies; D018570:Risk Assessment; D017201:Virus Shedding
chemical_list: D000998:Antiviral Agents; D053139:Oseltamivir