title: Current knowledge on porcine regulatory T cells.
abstract: Regulatory T cells (Tregs) are known in humans and mice from last 15 years, and several studies led to a detailed knowledge on their phenotype, functions, and role in various immune reactions. In swine, the existence of Tregs was first demonstrated in 2008 and research is still at the beginning. Nevertheless, basic information regarding phenotype, mechanisms and targets of suppression, as well as implications in transplantation and some diseases are available. Purpose of this review is to give a brief summary of the current knowledge about porcine Tregs.
authors: Institute of Immunology, Department of Pathobiology, University of Veterinary Medicine Vienna, Veterinärplatz 1, 1210 Vienna, Austria. tobias.kaeser@vetmeduni.ac.at
authors: Tobias
authors: T
authors: Käser
authors: Wilhelm
authors: W
authors: Gerner
authors: Kerstin
authors: K
authors: Mair
authors: Sabine E
authors: SE
authors: Hammer
authors: Martina
authors: M
authors: Patzl
authors: Armin
authors: A
authors: Saalmüller
mesh_terms: D000818:Animals; D051858:Forkhead Transcription Factors / Q000276:immunology; D006801:Humans; D007108:Immune Tolerance / Q000276:immunology; D013552:Swine / Q000276:immunology*; D050378:T-Lymphocytes, Regulatory / Q000276:immunology*
chemical_list: D051858:Forkhead Transcription Factors