title: [Application of platelet-enriched plasma for the prevention of cochleovestibular disorders associated with piston stapedoplasty].
abstract: The present study was designed to evaluate the influence of sealing the labyrinthine vestibule with platelet-enriched plasma (PEP) on the development of cochleovestibular complications following piston stapedoplasty. The platelet-rich plasma was prepared by single-step centrifugation of the whole venous blood. Analysis of the data obtained showed that the use of PEP for sealing the periprosthetic space after stapedoplasty reduces the risk of development of sensorineural hearing impairment compared with the application of fatty tissue for the same purpose or a freely positioned prosthesis. Moreover, the use of PEP decreases the probability of the development of tympanophonia and its intensity after piston stapedoplasty.
authors: F V
authors: FV
authors: Semenov
authors: T V
authors: TV
authors: Banashek-Meshcheriakova
mesh_terms: D000328:Adult; D015834:Cochlear Diseases / Q000209:etiology / Q000503:physiopathology / Q000517:prevention & control*; D005260:Female; D005500:Follow-Up Studies; D006309:Hearing / Q000502:physiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010040:Otosclerosis / Q000503:physiopathology / Q000601:surgery; D053657:Platelet-Rich Plasma; D011183:Postoperative Complications; D012189:Retrospective Studies; D013201:Stapes Surgery / Q000009:adverse effects*; D016896:Treatment Outcome; D015837:Vestibular Diseases / Q000209:etiology / Q000503:physiopathology / Q000517:prevention & control*; D055815:Young Adult