title: Post-exposure prophylaxis following sexual exposure to HIV: a seven-year retrospective analysis in a regional centre.
abstract: An audit of 72 patients presenting for post-exposure prophylaxis following sexual exposure (PEPSE) to HIV (68 genitourinary medicine and 4 accident & emergency) was conducted from 2003 to 2009. The principal indications for PEPSE included 27 (38%) unprotected intercourse (15/27 vaginal and 12/27 anal) with a known HIV-positive partner, 20 (28%) unprotected receptive anal sex with male partner of unknown status, 17 (24%) following sexual assault and three (4%) unprotected sex with a partner from an endemic country. Of those who commenced PEPSE, 92% did so within the recommended 72 hours. Concurrent sexually transmitted infection (STI) was diagnosed in 8.3% patients (6.9% non-gonococcal urethritis and 1.4% rectal chlamydia). Fifty (69%) patients attended for follow-up and only 8% of these did not complete treatment. Twenty-five (35%) patients attended for repeat serology at three months and 18 (25%) at six months. All of the patients followed up remained HIV-negative.
authors: Department of Genitourinary Medicine, Royal Victoria Hospital, Belfast, UK. ej_mccarty@hotmail.com
authors: E J
authors: EJ
authors: McCarty
authors: S
authors: S
authors: Quah
authors: R
authors: R
authors: Maw
authors: W W
authors: WW
authors: Dinsmore
authors: C R
authors: CR
authors: Emerson
mesh_terms: D005260:Female; D015658:HIV Infections / Q000453:epidemiology / Q000517:prevention & control* / Q000635:transmission; D006801:Humans; D015994:Incidence; D008297:Male; D056990:Post-Exposure Prophylaxis / Q000706:statistics & numerical data*; D012749:Sexually Transmitted Diseases / Q000517:prevention & control* / Q000635:transmission; D047568:Unsafe Sex