title: Reperfusion strategies for acute ischemic stroke.
abstract: Stroke remains a major cause of morbidity and mortality worldwide. Despite preventive measures, effective management strategies are needed to reduce the morbidity and mortality associated with this devastating condition. While the management of hemorrhagic stroke is mostly limited to supportive care, reperfusion strategies in ischemic stroke have been developed and continue to evolve. Conceptually, the pathophysiology of ischemic stroke is similar to that of acute myocardial infarction and the objective of management is similar (ie, to rapidly restore normal flow to reduce permanent damage). It is, therefore, not surprising that the management of acute ischemic stroke includes intravenous (IV) thrombolysis, the only Food and Drug Administration (FDA)-approved strategy at this point. In addition, there are a myriad of emerging endovascular interventional techniques. We review the current literature and discuss some of the technical aspects of endovascular therapy in the setting of acute ischemic stroke.
authors: St. Joseph Heart Institute, Lexington, KY, USA.
authors: Nezar
authors: N
authors: Falluji
authors: Alex
authors: A
authors: Abou-Chebl
authors: Carlos E Rodriguez
authors: CE
authors: Castro
authors: Debabrata
authors: D
authors: Mukherjee
mesh_terms: D017130:Angioplasty / Q000379:methods*; D057510:Endovascular Procedures / Q000379:methods*; D006801:Humans; D015424:Reperfusion / Q000379:methods*; D015607:Stents; D020521:Stroke / Q000188:drug therapy / Q000601:surgery*; D015912:Thrombolytic Therapy / Q000379:methods*