title: Two cases of reciprocal chromosomal translocation (4; 7)(p+; q-) (2; 8)(q-; q+) in piglets produced by ICSI.
abstract: In this study, the karyotypes of 14 piglets from four different litters produced by intracytoplasmic sperm injection (ICSI) and embryo transfer were analysed. The chromosome analysis was based on a classical cytogenetic examination following the standard protocols of lymphocyte cultures. Two cases of reciprocal translocation [(4; 7)(p+; q-) and (2; 8)(q-; q+)] were detected in two female transgenic piglets. These animals showed neither anatomical nor physiological alterations and had normal growth. To our knowledge, this is the first karyotype study of piglets produced by ICSI.
authors: Departamento de Fisiología, Facultad de Veterinaria, Universidad de Murcia, Spain. fagarcia@um.es
authors: F A
authors: FA
authors: García-Vázquez
authors: I
authors: I
authors: Hernández-Caravaca
authors: M
authors: M
authors: Martín
authors: E
authors: E
authors: Gómez
authors: A
authors: A
authors: Rodríguez
authors: R
authors: R
authors: Sánchez-Sánchez
authors: J
authors: J
authors: Gadea
mesh_terms: D000818:Animals; D030801:Animals, Genetically Modified; D005260:Female; D007621:Karyotyping / Q000662:veterinary; D020554:Sperm Injections, Intracytoplasmic / Q000009:adverse effects / Q000662:veterinary*; D013552:Swine / Q000235:genetics*; D014178:Translocation, Genetic / Q000235:genetics*