title: Developing disease activity and response criteria in connective tissue disease-related interstitial lung disease.
abstract: The interstitial lung diseases (ILD) are a group of heterogeneous diseases that exert significant morbidity and mortality in connective tissue diseases (CTD). There is no consensus on measures of disease activity or therapeutic responsiveness, which hampers effective drug development and regulatory evaluation of candidate therapies. The CTD-ILD Special Interest Group represents an international multidisciplinary effort to identify consensus on criteria to measure disease activity and therapeutic response in CTD-ILD. We summarize the design of the studies we are conducting and progress leading to the OMERACT 10 and 2010 EULAR meetings.
authors: Section of Rheumatology, Department of Medicine, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA. saketkoo.md@gmail.com
authors: Lesley Ann
authors: LA
authors: Saketkoo
authors: Eric L
authors: EL
authors: Matteson
authors: Kevin K
authors: KK
authors: Brown
authors: James R
authors: JR
authors: Seibold
authors: Vibeke
authors: V
authors: Strand
mesh_terms: D003240:Connective Tissue Diseases / Q000150:complications*; D006801:Humans; D017563:Lung Diseases, Interstitial / Q000209:etiology* / Q000628:therapy*; D017063:Outcome Assessment, Health Care / Q000379:methods / Q000639:trends*; D016032:Randomized Controlled Trials as Topic; D057566:Self Report; D012720:Severity of Illness Index; D016896:Treatment Outcome