title: Quality of life appears similar between survivors of indolent and aggressive non-Hodgkin lymphoma.
abstract: Few studies have examined the quality of life (QOL) in survivors of non-Hodgkin lymphoma (NHL). A total of 109 patients with NHL (58 aggressive [AGG], 51 indolent [IND]) completed two health-related QOL assessments using the Medical Outcomes Study 36-Item Short-Form Healthy Survey (MOS SF-36) and the Functional Assessment in Cancer Therapy - Fatigue (FACT-F). Scores between IND and AGG were compared using a two-sample t-test. Multiple linear regression was performed to account for any potentially explanatory variables. Overall, 70.6% had received chemotherapy and 55% had received immunotherapy. Some 17.6% of the IND group had received no therapy. The overall physical and mental component QOL scores of the SF-36 did not differ between survivors. Physical function in survivors of IND was significantly better when compared with that of AGG NHL. Our study reports a similar overall QOL between survivors of IND and AGG NHL. Physical function, however, may be more impaired in survivors of AGG NHL.
authors: Division of Hematology/Oncology/Transplantation, Department of Medicine, University of Minnesota, Minneapolis, MN 55455, USA. blaes004@umn.edu
authors: Anne H
authors: AH
authors: Blaes
authors: Linan
authors: L
authors: Ma
authors: Yan
authors: Y
authors: Zhang
authors: Bruce A
authors: BA
authors: Peterson
mesh_terms: D000328:Adult; D000368:Aged; D005221:Fatigue / Q000523:psychology; D005260:Female; D006306:Health Surveys; D006801:Humans; D016014:Linear Models; D008228:Lymphoma, Non-Hodgkin / Q000473:pathology / Q000523:psychology* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D011788:Quality of Life / Q000523:psychology*; D011795:Surveys and Questionnaires; D017741:Survivors / Q000523:psychology*