title: A tertiary amine as a hydride donor: trichlorosilyl triflate-mediated conjugate reduction of unsaturated ketones.
abstract: Bulky tertiary amines, especially dicyclohexylisobutylamine, smoothly reduced α,β-unsaturated ketones in the presence of trichlorosilyl triflate to give the corresponding saturated ketones in excellent yields. Isotope-labeling studies revealed that an α-hydrogen of the amine was transferred to the enones during reduction.
authors: Priority Organization for Innovation and Excellence, Kumamoto University, 5-1 Oe-honmachi, Kumamoto, 862-0973, Japan. skotani@gpo.kumamoto-u.ac.jp
authors: Shunsuke
authors: S
authors: Kotani
authors: Kazuki
authors: K
authors: Osakama
authors: Masaharu
authors: M
authors: Sugiura
authors: Makoto
authors: M
authors: Nakajima
mesh_terms: D000588:Amines / Q000737:chemistry*; D007659:Ketones / Q000737:chemistry*; D008698:Mesylates / Q000737:chemistry*; D015394:Molecular Structure; D010084:Oxidation-Reduction
chemical_list: D000588:Amines; D007659:Ketones; D008698:Mesylates