title: Rings D-seco and B,D-seco tetranortriterpenoids from root bark of Entandrophragma angolense.
abstract: Investigation of the root bark extract of Entandrophragma angolense led to identification of two gedunin-type limonoids 5-hydroxy-7-deacetoxy-7-oxogedunin and 5,6-dehydro-7-deacetoxy-7-oxogedunin, and three methyl angolensate derivatives, 6-deacetoxydomesticulide D, 6-deacetoxydomesticulide D 21-methylether, and entangosin, together with known compounds, methyl angolensate, 6-acetoxymethyl angolensate and secomahoganin. Their structures were established by extensive NMR experiments in conjunction with mass spectrometry. Entangosin is a rare example of a limonoid derivative having a fully O-substituted furan moiety.
authors: Department of Chemistry and Bioscience, Faculty of Science, Kagoshima University, 1-21-35 Korimoto, Kagoshima 890-0065, Japan.
authors: Tienabe K
authors: TK
authors: Nsiama
authors: Hiroaki
authors: H
authors: Okamura
authors: Toshiyuki
authors: T
authors: Hamada
authors: Yoshiki
authors: Y
authors: Morimoto
authors: Matsumi
authors: M
authors: Doe
authors: Tetsuo
authors: T
authors: Iwagawa
authors: Munehiro
authors: M
authors: Nakatani
mesh_terms: D005663:Furans / Q000737:chemistry*; D036701:Limonins / Q000737:chemistry* / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D029582:Meliaceae / Q000737:chemistry*; D015394:Molecular Structure; D024301:Plant Bark / Q000737:chemistry; D010936:Plant Extracts / Q000737:chemistry*; D018517:Plant Roots / Q000737:chemistry; D012632:Secosteroids / Q000737:chemistry / Q000302:isolation & purification; D014315:Triterpenes / Q000737:chemistry* / Q000302:isolation & purification
chemical_list: D005663:Furans; D036701:Limonins; D010936:Plant Extracts; D012632:Secosteroids; D014315:Triterpenes; C092741:methyl angolensate