title: Rosai-Dorfman disease of the paranasal sinuses and orbit.
abstract: Rosai-Dorfman disease, also known as sinus histiocytosis with massive lymphadenopathy, is a benign indolent disorder, characterized by enlarged lymph nodes filled with histiocytes. Extranodal involvement is uncommon. The disease rarely affects the nose and paranasal sinuses. We report a case that presented with a right nasal mass, extending into all the paranasal sinuses and right orbit without any accompanying lymphadenopathy. Because of the absence of lymphadenopathy it posed a diagnostic challenge until the pathology was confirmed on histopathological examination.
authors: Department of Hematology, Sir Ganga Ram Hospital, New Delhi, India. drafaqak@yahoo.co.in
authors: Afaq Ahmad
authors: AA
authors: Khan
authors: Fouzia
authors: F
authors: Siraj
authors: Devinder
authors: D
authors: Rai
authors: Shyam
authors: S
authors: Aggarwal
mesh_terms: D000328:Adult; D000970:Antineoplastic Agents / Q000627:therapeutic use; D003520:Cyclophosphamide / Q000627:therapeutic use; D005260:Female; D015618:Histiocytosis, Sinus / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology*; D006801:Humans; D009915:Orbit / Q000000981:diagnostic imaging / Q000473:pathology*; D010256:Paranasal Sinuses / Q000000981:diagnostic imaging / Q000473:pathology*; D011239:Prednisolone / Q000627:therapeutic use; D009418:S100 Proteins / Q000378:metabolism; D014057:Tomography, X-Ray Computed; D014750:Vincristine / Q000627:therapeutic use
chemical_list: D000970:Antineoplastic Agents; D009418:S100 Proteins; D014750:Vincristine; D003520:Cyclophosphamide; D011239:Prednisolone