title: Full assessment of fate and physiological behavior of quantum dots utilizing Caenorhabditis elegans as a model organism.
abstract: We evaluated the in vivo fate and physiological behavior of quantum dots (QDs) in Caenorhabditis elegans by GFP transfection, fluorescent imaging, synchrotron radiation based elemental imaging, and speciation techniques. The in situ metabolism and degradation of QDs in the alimentary system and long-term toxicity on reproduction are fully assessed. This work highlights the utility of the C. elegans model as a multiflexible platform to allow noninvasively imaging and monitoring in vivo consequences of engineered nanomaterials.
authors: CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology, Beijing 100190, China.
authors: Ying
authors: Y
authors: Qu
authors: Wei
authors: W
authors: Li
authors: Yunlong
authors: Y
authors: Zhou
authors: Xuefeng
authors: X
authors: Liu
authors: Lili
authors: L
authors: Zhang
authors: Liming
authors: L
authors: Wang
authors: Yu-Feng
authors: YF
authors: Li
authors: Atsuo
authors: A
authors: Iida
authors: Zhiyong
authors: Z
authors: Tang
authors: Yuliang
authors: Y
authors: Zhao
authors: Zhifang
authors: Z
authors: Chai
authors: Chunying
authors: C
authors: Chen
mesh_terms: D000818:Animals; D017173:Caenorhabditis elegans / Q000502:physiology*; D023421:Models, Animal; D008954:Models, Biological; D045663:Quantum Dots