title: Molecular targets in the design of antifibrotic therapy in chronic liver disease.
authors: Research Institute, Laboratory of Gastroenterology and Hepatology, Hospital Universitario 12 de Octubre, School of Medicine, Universidad Complutense de Madrid, Madrid, Spain. jsolis.hdoc@salud.madrid.org
authors: J A
authors: JA
authors: Solís Herruzo
authors: P
authors: P
authors: Solís-Muñoz
authors: T
authors: T
authors: Muñoz Yagüe
authors: I
authors: I
authors: García-Ruiz
mesh_terms: D000893:Anti-Inflammatory Agents / Q000494:pharmacology / Q000627:therapeutic use; D000975:Antioxidants / Q000627:therapeutic use; D003094:Collagen / Q000187:drug effects / Q000378:metabolism; D018450:Disease Progression; D015195:Drug Design; D005109:Extracellular Matrix / Q000187:drug effects* / Q000378:metabolism; D005353:Fibronectins / Q000378:metabolism; D055166:Hepatic Stellate Cells / Q000187:drug effects / Q000378:metabolism; D006801:Humans; D036341:Intercellular Signaling Peptides and Proteins / Q000627:therapeutic use; D016753:Interleukin-10 / Q000627:therapeutic use; D007797:Laminin / Q000378:metabolism; D008103:Liver Cirrhosis / Q000517:prevention & control*; D008107:Liver Diseases / Q000188:drug therapy* / Q000473:pathology; D058990:Molecular Targeted Therapy; D011509:Proteoglycans / Q000378:metabolism; D012084:Renin-Angiotensin System / Q000502:physiology; D014409:Tumor Necrosis Factor-alpha / Q000037:antagonists & inhibitors
chemical_list: D000893:Anti-Inflammatory Agents; D000975:Antioxidants; D005353:Fibronectins; D036341:Intercellular Signaling Peptides and Proteins; D007797:Laminin; D011509:Proteoglycans; D014409:Tumor Necrosis Factor-alpha; D016753:Interleukin-10; D003094:Collagen