title: Polychlorinated biphenyls (PCBs) in indoor air and in serum among older residents of upper Hudson River communities.
abstract: A study was conducted to evaluate the association between PCBs in residential indoor air and in the serum of older, long time residents of three upper Hudson River communities. Samples of indoor air and of serum were collected from 170 persons 55 to 74 years of age, and analyzed for PCBs using glass capillary gas chromatography. After adjusting for age, BMI, cigarette smoking, and Hudson River fish consumption with multiple linear regression analysis, the results indicated statistically significant associations between concentrations in indoor air and serum for PCB-28, a lightly chlorinated congener common in air that accumulates in serum, and PCB-105. Duration of exposure was an important factor, since among persons who had lived in their home for 39 years or more, 11 of the 12 most commonly detected congeners were significantly correlated, as was their sum (∑ PCB). Significant associations between indoor air and serum PCB concentrations also were more likely when collected in cooler months and if the two samples were collected within 20 d of each other. The study is among the first to indicate that PCB concentrations characteristic of residential indoor air are associated with a detectable increase in body burden.
authors: Department of Environmental Health Sciences, School of Public Health, University at Albany, State University of New York, Rensselaer, NY 12144, United States.
authors: Edward F
authors: EF
authors: Fitzgerald
authors: Srishti
authors: S
authors: Shrestha
authors: Patrick M
authors: PM
authors: Palmer
authors: Lloyd R
authors: LR
authors: Wilson
authors: Erin E
authors: EE
authors: Belanger
authors: Marta I
authors: MI
authors: Gomez
authors: Michael R
authors: MR
authors: Cayo
authors: Syni-An
authors: SA
authors: Hwang
mesh_terms: D000368:Aged; D016902:Air Pollution, Indoor / Q000032:analysis*; D001822:Body Burden; D015992:Body Mass Index; D002849:Chromatography, Gas / Q000379:methods; D004785:Environmental Pollutants / Q000032:analysis* / Q000097:blood*; D005260:Female; D005396:Fish Products; D006801:Humans; D008297:Male; D008875:Middle Aged; D009518:New York; D011078:Polychlorinated Biphenyls / Q000032:analysis* / Q000097:blood*; D012044:Regression Analysis
chemical_list: D004785:Environmental Pollutants; C067940:2,3,3',4,4'-pentachlorobiphenyl; C081766:2,4,4'-trichlorobiphenyl; D011078:Polychlorinated Biphenyls