title: Predictors of mortality following severe pelvic ring fracture: results of a population-based study.
abstract: BACKGROUND
  Traumatic disruption of the pelvic ring is uncommon but is associated with a high risk of mortality. These injuries are predominantly due to high energy blunt trauma such as a fall from height, road or workplace trauma, and severe associated injuries are prevalent, increasing the complexity of managing this patient group. The aim of this population-based study was to investigate predictors of mortality following severe pelvic ring fractures managed in an inclusive, regionalised trauma system.
  
  
  METHODS
  Cases aged≥15 years from 1st July 2001 to 30th June 2008 were extracted from the population-based statewide Victorian State Trauma Registry for analysis. Patient demographic, prehospital and admission characteristics were considered as potential predictors of mortality. Multivariate logistic regression was used to identify predictors of mortality with adjusted odds ratios (AOR) and 95% confidence intervals (CI) calculated.
  
  
  RESULTS
  There were 348 cases over the 8-year period. The mortality rate was 19%. Patients aged≥65 years were at higher odds of mortality (AOR 7.6, 95% CI: 2.8, 20.4) than patients aged 15-34 years. Patients hypotensive at the scene (AOR 5.5, 95% CI: 2.3, 13.2), and on arrival at the definitive hospital of care (AOR 3.7, 955 CI: 1.7, 8.0), were more likely to die than patients without hypotension. The presence of a severe chest injury was associated with an increased odds of mortality (AOR 2.8, 95% CI: 1.3, 6.1), whilst patients injured in intentional events were also more likely to die than patients involved in unintentional events (AOR 4.9, 95% CI: 1.6, 15.6). There was no association between the hospital of definitive management and mortality after adjustment for other variables, despite differences in the protocols for managing these patients at the major trauma services (Level 1 trauma centres).
  
  
  CONCLUSIONS
  The findings highlight the importance of effective control of haemodynamic instability for reducing the risk of mortality. As most patients survive these injuries, further research should focus on long term morbidity and the impact of different treatment approaches.
authors: Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Australia. belinda.gabbe@monash.edu
authors: Belinda J
authors: BJ
authors: Gabbe
authors: Richard
authors: R
authors: de Steiger
authors: Max
authors: M
authors: Esser
authors: Andrew
authors: A
authors: Bucknill
authors: Matthias K
authors: MK
authors: Russ
authors: Peter A
authors: PA
authors: Cameron
mesh_terms: D015998:Abbreviated Injury Scale; D000059:Accidents / Q000401:mortality; D000293:Adolescent; D000328:Adult; D000368:Aged; D001315:Australia / Q000453:epidemiology; D004632:Emergency Medical Services / Q000458:organization & administration; D005260:Female; D050723:Fractures, Bone / Q000401:mortality*; D006439:Hemodynamics; D006470:Hemorrhage / Q000401:mortality / Q000628:therapy; D006801:Humans; D007022:Hypotension / Q000401:mortality; D008297:Male; D008875:Middle Aged; D009104:Multiple Trauma / Q000401:mortality; D010384:Pelvic Bones / Q000293:injuries*; D012307:Risk Factors; D016728:Self-Injurious Behavior / Q000401:mortality; D013898:Thoracic Injuries / Q000401:mortality; D014193:Trauma Centers / Q000706:statistics & numerical data; D014739:Victoria / Q000453:epidemiology; D014949:Wounds, Nonpenetrating / Q000401:mortality; D055815:Young Adult