title: A novel spectrofluorometric method for the determination of methiocarb using an amphiphilic p-sulfonatocalix[4]arene.
abstract: The characteristics of host-guest complexation between tetrabutyl ether derivatives of p-sulfonatocalix[4]arene (SC4Bu) and methiocarb [3,5-dimethyl-4-(methylthio) phenyl methylcarbamate] were investigated by fluorescence spectrometry. Upon addition of methiocarb, the fluorescence intensity of SC4Bu was quenched regularly and a slight red shift was observed for the maximum emission peak. These results indicated that the SC4Bu-methiocarb complex was formed a 1:1 mole ratio. An association constant of 1.67×10(4) L mol(-1) was calculated by applying a deduced equation. The interaction mechanism of the inclusion complex was discussed. Based on the results, a novel spectrofluorimetric method was described for the determination of methiocarb with a detection limit at 0.05 μg mL(-1). This method is very simple and shows high sensitivity and selectivity. Moreover, the proposed method was successfully applied to the determination of methiocarb in water samples.
authors: Anhui Key Laboratory of Chemo-Biosensing, College of Chemistry and Materials Science, Anhui Normal University, Wuhu 241000, PR China.
authors: Xue-Ping
authors: XP
authors: Ding
authors: Dong-Bao
authors: DB
authors: Tang
authors: Tao
authors: T
authors: Li
authors: Su-Fan
authors: SF
authors: Wang
authors: Yun-You
authors: YY
authors: Zhou
mesh_terms: D047250:Calixarenes / Q000737:chemistry* / Q000494:pharmacology*; D004347:Drug Interactions; D008714:Methiocarb / Q000032:analysis*; D008954:Models, Biological; D008958:Models, Molecular; D010636:Phenols / Q000737:chemistry* / Q000494:pharmacology*; D012680:Sensitivity and Specificity; D013050:Spectrometry, Fluorescence / Q000379:methods; D013501:Surface-Active Agents / Q000737:chemistry / Q000494:pharmacology; D013816:Thermodynamics
chemical_list: D010636:Phenols; D013501:Surface-Active Agents; C511968:p-sulfonatocalix(4)arene; D047250:Calixarenes; D008714:Methiocarb