title: Mechanistic understanding of multistep assembly of DNA with a carbazole ligand by simple adjustment of host-guest concentrations.
abstract: Two alternative binding states are identified in interaction of calf thymus DNA with a partially hydrophobic carbazole ligand [(Im(+))(2)Cz], where biphasic UV-vis and circular dichroic (CD) spectral changes are apparent during the titration of calf thymus DNA with the carbazole ligand.
authors: Nara Institute of Science and Technology, 8916-5 Takayama, Ikoma, Nara 630-0192, Japan.
authors: Norie
authors: N
authors: Inukai
authors: Tsuyoshi
authors: T
authors: Kawai
authors: Junpei
authors: J
authors: Yuasa
mesh_terms: D000818:Animals; D001665:Binding Sites; D002227:Carbazoles / Q000737:chemistry / Q000378:metabolism*; D002417:Cattle; D002942:Circular Dichroism; D004247:DNA / Q000737:chemistry / Q000378:metabolism*; D008024:Ligands; D013056:Spectrophotometry, Ultraviolet
chemical_list: D002227:Carbazoles; D008024:Ligands; C041514:carbazole; D004247:DNA; C427203:calf thymus DNA