title: Bacteriophage therapy for refractory Pseudomonas aeruginosa urinary tract infection.
abstract: We describe the success of adjunctive bacteriophage therapy for refractory Pseudomonas aeruginosa urinary tract infection in the context of bilateral ureteric stents and bladder ulceration, after repeated failure of antibiotics alone. No bacteriophage-resistant bacteria arose, and the kinetics of bacteriophage and bacteria in urine suggest self-sustaining and self-limiting infection.
authors: Centre for Infectious Diseases and Microbiology, Sydney West Area Health Service, NSW 2145, Australia.
authors: A
authors: A
authors: Khawaldeh
authors: Special Phage Services Pty, Brookvale, Sydney, NSW, Australia.
authors: S
authors: S
authors: Morales
authors: Centre for Infectious Diseases and Microbiology, Sydney West Area Health Service, NSW 2145, Australia.
authors: B
authors: B
authors: Dillon
authors: Eliava Institute of Bacteriophage, Microbiology and Virology, Georgian Academy of Sciences, Tbilisi, Democratic Republic of Georgia.
authors: Z
authors: Z
authors: Alavidze
authors: Centre for Infectious Diseases and Microbiology, Sydney West Area Health Service, NSW 2145, Australia.
authors: A N
authors: AN
authors: Ginn
authors: Centre for Infectious Diseases and Microbiology, Sydney West Area Health Service, NSW 2145, Australia.
authors: L
authors: L
authors: Thomas
authors: Centre for Infectious Diseases and Microbiology, Sydney West Area Health Service, NSW 2145, Australia.
authors: S J
authors: SJ
authors: Chapman
authors: GEEPhage, CHI Villeneuve St Georges, Villeneuve St Georges, France.
authors: A
authors: A
authors: Dublanchet
authors: Special Phage Services Pty, Brookvale, Sydney, NSW, Australia.
authors: A
authors: A
authors: Smithyman
authors: Sydney Institute for Emerging Infection and Biotechnology, University of Sydney at Westmead Hospital, NSW 2145, Australia.|Centre for Infectious Diseases and Microbiology, Sydney West Area Health Service, NSW 2145, Australia.
authors: J R
authors: JR
authors: Iredell
mesh_terms: D000368:Aged; D001435:Bacteriophages / Q000276:immunology*; D015169:Colony Count, Microbial; D004269:DNA, Bacterial / Q000737:chemistry / Q000235:genetics; D005260:Female; D006801:Humans; D016133:Polymerase Chain Reaction; D011552:Pseudomonas Infections / Q000276:immunology / Q000382:microbiology* / Q000628:therapy / Q000652:urine; D011550:Pseudomonas aeruginosa / Q000235:genetics / Q000276:immunology*; D012336:RNA, Ribosomal, 16S / Q000737:chemistry / Q000235:genetics; D014552:Urinary Tract Infections / Q000276:immunology / Q000382:microbiology* / Q000628:therapy / Q000652:urine
chemical_list: D004269:DNA, Bacterial; D012336:RNA, Ribosomal, 16S