title: First-in-man transcatheter aortic valve implantation of a 20-mm Edwards SAPIEN XT valve: one step forward for the treatment of patients with severe aortic stenosis and small aortic annulus.
abstract: We present the case of an 85-year-old woman diagnosed with severe aortic stenosis, porcelain aorta, and a small aortic annulus (17.3 mm), who underwent successful transfemoral transcatheter aortic valve implantation (TAVI) with a 20-mm Edwards SAPIEN XT valve using the NovaFlex+ delivery system. At 1-month follow-up the patient was in NYHA functional class I, and Doppler echocardiography showed a mean residual gradient of 15 mm Hg and trivial paravalvular aortic regurgitation. This case, which shows for the first time the feasibility of TAVI with a 20-mm valve, opens a new avenue for the challenging treatment of patients with aortic stenosis and a small aortic annulus.
authors: Quebec Heart & Lung Institute, Quebec city, Quebec, Canada. josep.rodes@criucpq.ulaval.ca
authors: Josep
authors: J
authors: Rodés-Cabau
authors: Robert
authors: R
authors: DeLarochellière
authors: Eric
authors: E
authors: Dumont
mesh_terms: D000368:Aged; D000792:Angiography / Q000379:methods; D001021:Aortic Valve / Q000000981:diagnostic imaging* / Q000473:pathology; D001024:Aortic Valve Stenosis / Q000000981:diagnostic imaging / Q000601:surgery*; D002404:Catheterization / Q000379:methods*; D017548:Echocardiography, Transesophageal / Q000379:methods; D005260:Female; D005500:Follow-Up Studies; D006350:Heart Valve Prosthesis; D019918:Heart Valve Prosthesis Implantation / Q000379:methods*; D006801:Humans; D011474:Prosthesis Design; D019233:Retreatment; D018570:Risk Assessment; D012720:Severity of Illness Index; D016896:Treatment Outcome