title: Late gadolinium enhancement from cardiac magnetic resonance in ischemic and non-ischemic cardiomyopathy.
abstract: BACKGROUND
  Diagnosis of coronary artery disease in patients with heart failure with systolic dysfunction usually requires coronary angiography. Cardiac magnetic resonance (CMR) is an accurate tool for the assessment of myocardial scar which may be the major cause of left ventricular systolic dysfunction.
  
  
  OBJECTIVE
  This study was to determine the prevalence and the difference in pattern of late gadolinium enhancement (LGE) between patients with ischemic (ICM) and non-ischemic cardiomyopathy (NICM).
  
  
  METHODS
  We enrolled 98 patients with heart failure and left ventricular systolic dysfunction with left ventricular ejection fraction less than 50%. Allpatients underwent CMR. CMR protocol included functional study and assessment of LGE. Left ventricular volume and ejection fraction was measured. The presence and extent of LGE including its pattern were assessed.
  
  
  RESULTS
  There were 58 patients with ICM and 40 patients with NICM. Patients with NICM had a lower left ventricular ejection fraction than those with ICM with a similar left ventricular wall thickness. LGE was detected in 53 patients with ICM (91.5%) and 10 patients with NICM (25%). LGE pattern was transmural or subendocardial pattern in patients with ICM and midwall scar in those with NICM.
  
  
  CONCLUSIONS
  The presence and pattern ofLGE can differentiate systolic heart failure from ICM and NICM.
authors: Division of Cardiology, Department of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand. sirkt@mahidol.ac.th
authors: Rungroj
authors: R
authors: Krittayaphong
authors: Thananya
authors: T
authors: Boonyasirinant
authors: Pairash
authors: P
authors: Saiviroonporn
authors: Suthipol
authors: S
authors: Udompunturak
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D009202:Cardiomyopathies / Q000150:complications / Q000175:diagnosis*; D016022:Case-Control Studies; D003287:Contrast Media; D005260:Female; D005682:Gadolinium; D006333:Heart Failure / Q000175:diagnosis* / Q000209:etiology; D006801:Humans; D007089:Image Enhancement; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000175:diagnosis*; D011237:Predictive Value of Tests; D013318:Stroke Volume; D018487:Ventricular Dysfunction, Left / Q000150:complications / Q000175:diagnosis
chemical_list: D003287:Contrast Media; D005682:Gadolinium