title: Minor pregnanes from Caralluma adscendens var. gracilis and Caralluma pauciflora.
abstract: Phytochemical investigation of Caralluma adscendens var. gracilis and Caralluma pauciflora (Asclepiadaceae) whole plant extracts allowed to isolate one pregnane glycoside and two pregnanes characterized as 12β,20-O-dibenzoyl-5α,6-dihydrosarcostin β-oleandropyranosyl-(1→4)-β-cymaropyranosyl-(1→4)-β-digitoxypyranosyl-(1→4)-β-cymaropyranosyl-(1→4)-β-cymaropyranoside (1), 12β-O-benzoyl-3β,11α,14β,20R-pentahydroxy-pregn-5-ene (2), and 11α-O-benzoyl-3β,12β,14β,20R-pentahydroxy-pregn-5-ene (3), respectively. Their structural characterization was obtained on the basis of extensive NMR spectral studies. Three known pregnane glycosides along with lupeol and β-sitosterol were also isolated and characterized.
authors: Department of Chemistry, Kakatiya University, Warangal-506009, Andhra Pradesh, India.
authors: Kommidi Devendar
authors: KD
authors: Reddy
authors: Belvotagi Venkatrao Adavi
authors: BV
authors: Rao
authors: Gummadi Sridhar
authors: GS
authors: Babu
authors: Bobbala Ravi
authors: BR
authors: Kumar
authors: Alessandra
authors: A
authors: Braca
authors: Antonio
authors: A
authors: Vassallo
authors: Nunziatina
authors: N
authors: De Tommasi
authors: Ghanakota Venkateshwar
authors: GV
authors: Rao
authors: Achanta Venkata Narasimha Appa
authors: AV
authors: Rao
mesh_terms: D029062:Apocynaceae / Q000737:chemistry*; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D053978:Pentacyclic Triterpenes / Q000737:chemistry / Q000302:isolation & purification; D010936:Plant Extracts / Q000737:chemistry*; D011278:Pregnanes / Q000737:chemistry / Q000302:isolation & purification*; D012855:Sitosterols / Q000737:chemistry / Q000302:isolation & purification; D000094042:Lupanes
chemical_list: D006027:Glycosides; D053978:Pentacyclic Triterpenes; D010936:Plant Extracts; D011278:Pregnanes; D012855:Sitosterols; C570391:11alpha-O-benzoyl-3beta,12beta,14beta,20R-pentahydroxy-pregn-5-ene; C570389:12beta,20-O-dibenzoyl-5alpha,6-dihydrosarcostin beta-oleandropyranosyl-(1-4)-beta-cymaropyranosyl-(1-4)-beta-digitoxypyranosyl-(1-4)-beta-cymaropyranosyl-(1-4)-beta-cymaropyranoside; C570390:12beta-O-benzoyl-3beta,11alpha,14beta,20R-pentahydroxy-pregn-5-ene; C025473:gamma-sitosterol; C010480:lupeol; D000094042:Lupanes