title: [Research progress of viscosupplementation].
abstract: OBJECTIVE
  To carry out a comprehensive and objective evaluation of viscosupplementation, so as to provide the actual judgments of effectiveness, development trends, and direction.
  
  
  METHODS
  The related literature was reviewed, and the keys were the assessments from the international relevant advisory bodies and insurance companies and the evidence-based medicine on clinic.
  
  
  RESULTS
  Viscosupplementation has been gradually accepted. Although there are many different clinical views of the viscosupplementation in the molecular weight of hyaluronan, injection dose, and the indications, intra-articular injection of hyaluronan for the treatment of osteoarthritis is well accepted.
  
  
  CONCLUSIONS
  Viscosupplementation is one of the methods of treating osteoarthritis. As it has been already verified that hyaluronan is effective in treating osteoarthritis of the knee and the periarthritis of shoulder, the hip joint injection is gradually recognized, and other small joints are going gradually.
authors: Pharmaceutical Corporation Limited, Shanghai 201908, PR China. qishenggu@163.com
authors: Qisheng
authors: Q
authors: Gu
authors: Ninghui
authors: N
authors: Zhou
authors: Jingfeng
authors: J
authors: Shanghai
mesh_terms: D006801:Humans; D006820:Hyaluronic Acid / Q000627:therapeutic use*; D010003:Osteoarthritis / Q000628:therapy*; D016896:Treatment Outcome; D055676:Viscosupplementation / Q000379:methods*
chemical_list: D006820:Hyaluronic Acid