title: Acute kidney injury in primary nephrotic syndrome: report of nine cases in Siriraj Hospital.
abstract: Acute kidney injury is a rare but important complication of nephrotic syndrome. We demonstrated here nine patients with nephrotic syndrome and oliguric renal failure in Siriraj Hospital during 2007-2009. Renal biopsy was done in every patient. The results were focal and segmental glomerulosclerosis (FSGS) in three patients, minimal change disease in four patients and collapsing focal segmental glomerulosclerosis in two patients. Seven patients had dramatic response to corticosteroid treatment within a few weeks and had rapid recovery of renal function. The exact mechanism of idiopathic renal failure is not well understood but it might be related to reduction in ultrafiltration coefficient of the glomeruli.
authors: Division of Nephrology, Department of Medicine, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand.
authors: Nuttasith
authors: N
authors: Larpparisuth
authors: Thawee
authors: T
authors: Chanchairujira
authors: Ratana
authors: R
authors: Chawanasuntorapoj
authors: Bunyarit
authors: B
authors: Choensuchon
authors: Kriengsak
authors: K
authors: Vareesangthip
authors: Somkiat
authors: S
authors: Vasuvattakul
authors: Tanyarat
authors: T
authors: Teerapornlertratt
mesh_terms: D058186:Acute Kidney Injury / Q000209:etiology*; D001706:Biopsy; D003404:Creatinine / Q000097:blood; D005260:Female; D005500:Follow-Up Studies; D005923:Glomerulosclerosis, Focal Segmental / Q000150:complications / Q000473:pathology*; D005938:Glucocorticoids / Q000627:therapeutic use*; D006784:Hospitals, Teaching; D006801:Humans; D007668:Kidney / Q000473:pathology; D007677:Kidney Function Tests; D008297:Male; D008875:Middle Aged; D009404:Nephrotic Syndrome / Q000150:complications / Q000473:pathology*; D011239:Prednisolone / Q000627:therapeutic use*; D011507:Proteinuria / Q000175:diagnosis; D016896:Treatment Outcome
chemical_list: D005938:Glucocorticoids; D011239:Prednisolone; D003404:Creatinine