title: [Inflammatory bowel diseases: gynecological and obstetrical considerations].
abstract: Inflammatory bowel diseases (IBD), including Crohn's disease and ulcerative colitis, are invalidating inflammatory affections, which evolve by relapse interrupted with clinical remission. Crohn's disease commonly affects young women in their reproductive years with a peak of incidence between 20 and 30. Infertility and sexual dysfunction are equivalent to that of the general population while they are increasing in patients with active IBD or after colorectal surgery. IBD are well controlled by medical treatments and the frequency of relapse during the pregnancy is similar to that of the non-pregnant IBD patients. The data concerning the risk of congenital malformations in IBD are contradictory. The risk of preterm delivery and low birth weight is significantly increased and correlated to the disease activity. When a medical treatment insures a quiescent disease before the pregnancy, it is advisable to continue it during the pregnancy because the benefits of controlled disease outweigh the risks of medication. IBD, possible perianal lesions and colorectal surgical interventions influence the mode of delivery, but the indication of caesarean section should primarily be governed by obstetric necessity. Preconceptional counseling seems desirable because of the risks during pregnancy, according to the disease activity, the surgical histories and the therapeutic agents.
authors: Service de gynécologie obstétrique, hôpital Beaujon, AP-HP, université Paris-VII, 100, boulevard du Général-Leclerc, 92110 Clichy, France.
authors: P
authors: P
authors: Amate
authors: M
authors: M
authors: Seirafi
authors: Y
authors: Y
authors: Bouhnik
authors: D
authors: D
authors: Luton
authors: G
authors: G
authors: Ducarme
mesh_terms: D000328:Adult; D002585:Cesarean Section / Q000706:statistics & numerical data*; D000013:Congenital Abnormalities / Q000453:epidemiology / Q000209:etiology; D005260:Female; D005765:Gastrointestinal Agents / Q000627:therapeutic use; D006801:Humans; D015994:Incidence; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D007247:Infertility, Female / Q000453:epidemiology / Q000209:etiology; D015212:Inflammatory Bowel Diseases / Q000150:complications / Q000188:drug therapy / Q000453:epidemiology* / Q000601:surgery; D011247:Pregnancy; D011248:Pregnancy Complications / Q000453:epidemiology* / Q000209:etiology; D047928:Premature Birth / Q000453:epidemiology*; D012008:Recurrence; D012306:Risk; D012735:Sexual Dysfunction, Physiological / Q000453:epidemiology / Q000209:etiology; D055815:Young Adult
chemical_list: D005765:Gastrointestinal Agents