title: Generalized pulp stones: report of a case with 6-year follow-up.
abstract: OBJECTIVE
  To present a mildly mentally retarded patient with generalized pulp stone formation and the six-year follow-up and to discuss the differential diagnosis of the case.
  
  
  CONCLUSIONS
  Pulp stones were radiographically detected in the pulp chamber of all permanent teeth in a 25-year-old woman with mild mental retardation who presented for endodontic treatment on tooth no 11 (FDI). The patient's medical, dental and family history was noncontributory. The pulp stone in the pulp chamber of tooth no 11 was removed during canal filing, and root canal treatment completed uneventfully. Six years later, the patient was re-evaluated and the pulp stones were unchanged radiographically. The patient's family history, facial phenotype and karyotype as well as the radiographic, laboratory and physical examination were not consistent with any of the known genetic syndromes associated with generalized pulp stones. Molecular analysis for the DSPP gene proved negative. The aetiology of this case remains unknown.
  
  
  CONCLUSIONS
  Generalized pulp stones occur rarely; Such patients should be referred for genetic evaluation because pulp stones are mostly associated with genetic dentine defects; Pulp stones may hinder root canal treatment; Pulp stones may remain unchanged overtime.
authors: Department of Oral Diagnosis and Radiology, School of Dentistry, University of Athens, Athens, Greece.
authors: C
authors: C
authors: Donta
authors: K
authors: K
authors: Kavvadia
authors: P
authors: P
authors: Panopoulos
authors: S
authors: S
authors: Douzgou
mesh_terms: D000328:Adult; D058070:Asymptomatic Diseases; D003784:Dental Pulp Calcification / Q000175:diagnosis* / Q000235:genetics; D003791:Dental Pulp Test; D016326:Extracellular Matrix Proteins / Q000032:analysis; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007180:Incisor / Q000473:pathology*; D008607:Intellectual Disability / Q000150:complications; D008437:Maxilla; D010750:Phosphoproteins / Q000032:analysis; D016300:Radiography, Bitewing; D011862:Radiography, Panoramic; D012390:Root Canal Therapy; D012795:Sialoglycoproteins / Q000032:analysis; D000099311:Dentin Sialophosphoprotein
chemical_list: D016326:Extracellular Matrix Proteins; D010750:Phosphoproteins; D012795:Sialoglycoproteins; D000099311:Dentin Sialophosphoprotein