title: Fast CEC-MS using poly(dimethylsiloxane) microinjector, short packed column, and low-sheath-flow interface.
abstract: A fast CEC-MS approach based on a microinjector and a short CEC column was developed. Poly(dimethylsiloxane) was used as the substrate for microinjector fabrication. A short capillary column (∼5 cm) packed with 5 μm octadecyl silica particles was inserted into the microinjector. The microinjector CEC device was interfaced to ESI-MS using a low-flow sheath liquid interface. The device delivers the advantages of sample introduction, pre-concentration, elution, and fast analysis as in chip-CEC yet avoids the difficulty of packing stationary material into the chip. The online pre-concentration and CEC-MS analysis capabilities of this device were demonstrated by analysis of a six-triazine mixture. A signal enhancement of 20-99-fold was achieved with a sample loading time of 180 s.
authors: Department of Chemistry, National Taiwan University, Taipei, Taiwan.
authors: Chao-Jung
authors: CJ
authors: Chen
authors: Che-Wei
authors: CW
authors: Wang
authors: Guor-Rong
authors: GR
authors: Her
mesh_terms: D053801:Capillary Electrochromatography; D004129:Dimethylpolysiloxanes / Q000737:chemistry*; D013058:Mass Spectrometry; D008845:Microinjections / Q000295:instrumentation / Q000379:methods*; D014227:Triazines / Q000032:analysis*
chemical_list: D004129:Dimethylpolysiloxanes; D014227:Triazines; C013830:baysilon