title: Full-length genomic sequence of hepatitis B virus genotype C2 isolated from a native Brazilian patient.
abstract: The hepatitis B virus (HBV) is among the leading causes of chronic hepatitis, cirrhosis and hepatocellular carcinoma. In Brazil, genotype A is the most frequent, followed by genotypes D and F. Genotypes B and C are found in Brazil exclusively among Asian patients and their descendants. The aim of this study was to sequence the entire HBV genome of a Caucasian patient infected with HBV/C2 and to infer the origin of the virus based on sequencing analysis. The sequence of this Brazilian isolate was grouped with four other sequences described in China. The sequence of this patient is the first complete genome of HBV/C2 reported in Brazil.
authors: Departamento de Gastroenterologia, Instituto de Medicina Tropical, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brasil. monica.viviana@usp.br
authors: Mónica Viviana
authors: MV
authors: Alvarado-Mora
authors: Rúbia Anita Ferraz
authors: RA
authors: Santana
authors: Roberta
authors: R
authors: Sitnik
authors: Paulo Roberto Abrão
authors: PR
authors: Ferreira
authors: Cristovão Luís Pitangueira
authors: CL
authors: Mangueira
authors: Flair José
authors: FJ
authors: Carrilho
authors: João Renato Rebello
authors: JR
authors: Pinho
mesh_terms: D001938:Brazil; D004279:DNA, Viral / Q000235:genetics; D005260:Female; D016679:Genome, Viral / Q000235:genetics*; D005838:Genotype; D006515:Hepatitis B virus / Q000235:genetics* / Q000302:isolation & purification; D019694:Hepatitis B, Chronic / Q000821:virology*; D006801:Humans; D008875:Middle Aged
chemical_list: D004279:DNA, Viral