title: Patients with borderline personality disorder and major depressive disorder are not distinguishable by their neuropsychological performance: a case-control study.
abstract: OBJECTIVE
  Patients with borderline personality disorder (BPD) and patients with major depressive disorder (MDD) exhibit a broad range of neuropsychological deficits. Studies in both groups of patients point to differences but also similarities. However, studies that compare both patient groups are missing from the literature. The present study aimed to compare neuropsychological functioning in BPD and MDD patients.
  
  
  METHODS
  Eighteen patients with BPD, 27 patients with MDD, 17 patients with BPD and MDD, and 76 healthy control subjects were included in the case-control study. Patients were treated for their disorders as inpatients of the Clinic of Psychiatry and Psychotherapy Bethel, Ev. Hospital Bielefeld (Bielefeld, Germany). All patients met DSM-IV diagnoses as assessed by trained psychotherapists within the first week of their admission. In addition to a comprehensive neuropsychological test battery, the inhibitory control of emotional stimuli was assessed. Data were collected between June 2004 and June 2007.
  
  
  RESULTS
  Patients showed only a few impairments and no increased distractibility toward emotionally negative stimuli. Patients with BPD and patients with MDD were not distinguishable by the neuropsychological test results.
  
  
  CONCLUSIONS
  These data did not support the notion of specific neuropsychological profiles in BPD and MDD. Future research needs to clarify the overlap of symptoms between both disorders.
authors: Division of Research, Evaluation and Documentation, Department of Psychiatry and Psychotherapy Bethel, Ev. Hospital Bielefeld, Bielefeld, Germany. thomas.beblo@evkb.de
authors: Thomas
authors: T
authors: Beblo
authors: Christoph
authors: C
authors: Mensebach
authors: Katja
authors: K
authors: Wingenfeld
authors: Nina
authors: N
authors: Rullkoetter
authors: Nicole
authors: N
authors: Schlosser
authors: Diplpsych
authors: Martin
authors: M
authors: Driessen