title: Successful treatment of parapneumonic empyema after H1N1 infection in a heart transplant recipient.
abstract: Pandemic influenza A H1N1 virus is likely to cause severe disease in patients who have received solid organs transplants. In these patients pneumonia is the most frequent clinical feature. Parapneumonic empyema (PPE) may represent the evolution of secondary bacterial respiratory infections. To our knowledge this is the first reported case of PPE during H1N1 influenza A in an adult heart transplanted patient. The patient was treated successfully with surgical empyemectomy and lung decortication, broad-spectrum antibiotics and oseltamivir. Eradication of influenza was obtained in the fifth postoperative day.
authors: Department of Thoracic Surgery and Heart and Lung Transplantation Program, S. Orsola-Malpighi University Hospital, Bologna, Italy. dellamore76@libero.it
authors: Andrea
authors: A
authors: Dell'Amore
authors: Nizar
authors: N
authors: Asadi
authors: Giampiero
authors: G
authors: Dolci
authors: Franco
authors: F
authors: Stella
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D000998:Antiviral Agents / Q000627:therapeutic use*; D002311:Cardiomyopathy, Dilated / Q000601:surgery; D003131:Combined Modality Therapy; D016724:Empyema, Pleural / Q000175:diagnosis / Q000628:therapy* / Q000821:virology; D016027:Heart Transplantation / Q000009:adverse effects*; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects; D053118:Influenza A Virus, H1N1 Subtype / Q000472:pathogenicity*; D008297:Male; D053139:Oseltamivir / Q000627:therapeutic use*; D011024:Pneumonia, Viral / Q000175:diagnosis / Q000628:therapy* / Q000821:virology; D013510:Pulmonary Surgical Procedures; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D000998:Antiviral Agents; D007166:Immunosuppressive Agents; D053139:Oseltamivir