title: Stem cell-biomaterial interactions for regenerative medicine.
abstract: The synergism of stem cell biology and biomaterial technology promises to have a profound impact on stem-cell-based clinical applications for tissue regeneration. Biomaterials development is rapidly advancing to display properties that, in a precise and physiological fashion, could drive stem-cell fate both in vitro and in vivo. Thus, the design of novel materials is trying to recapitulate the molecular events involved in the production, clearance and interaction of molecules within tissue in pathologic conditions and regeneration of tissue/organs. In this review we will report on the challenges behind translating stem cell biology and biomaterial innovations into novel clinical therapeutic applications for tissue and organ replacements (graphical abstract).
authors: Department of Experimental Medicine and Biochemical Science, University of Perugia, Perugia, Italy. martinos@unipg.it
authors: Sabata
authors: S
authors: Martino
authors: Francesco
authors: F
authors: D'Angelo
authors: Ilaria
authors: I
authors: Armentano
authors: Josè Maria
authors: JM
authors: Kenny
authors: Aldo
authors: A
authors: Orlacchio
mesh_terms: D000818:Animals; D001672:Biocompatible Materials; D006801:Humans; D044968:Regenerative Medicine / Q000379:methods*; D057905:Stem Cell Research; D013234:Stem Cells / Q000166:cytology*; D023822:Tissue Engineering
chemical_list: D001672:Biocompatible Materials