title: Herpes simplex virus type 2 seroprevalence and incidence in acute and chronic HIV-1 infection.
abstract: Herpes simplex virus type 2 (HSV-2) HIV co-infection is common and associated with increased risk of HIV transmission. HSV-2 seroprevalence was assessed on stored samples from baseline and one year follow-up from 81 patients identified with acute HIV infection and 81 age-matched chronically infected men. HSV-2 seroprevalence at baseline was lower for those with acute rather than chronic HIV-infection, 51.9 versus 71.6% (P = 0.01); relative risk 0.72 (95% confidence interval [CI] 0.57-0.92). Since HSV-2 seroprevalence is lower in those newly HIV-infected, the diagnosis of early HIV infection may allow for counselling to reduce subsequent HSV-2 acquisition.
authors: Division of HIV Medicine and Infectious Diseases at Harbor-UCLA Medical Center, Los Angeles, CA, USA.
authors: M
authors: M
authors: Lagnese
authors: E S
authors: ES
authors: Daar
authors: P
authors: P
authors: Christenson
authors: G
authors: G
authors: Rieg
mesh_terms: D000208:Acute Disease / Q000453:epidemiology; D000328:Adult; D000914:Antibodies, Viral / Q000097:blood; D018791:CD4 Lymphocyte Count; D002908:Chronic Disease / Q000453:epidemiology; D015331:Cohort Studies; D015658:HIV Infections / Q000453:epidemiology* / Q000821:virology; D006561:Herpes Simplex / Q000453:epidemiology* / Q000821:virology; D018258:Herpesvirus 2, Human; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D016036:Seroepidemiologic Studies; D019562:Viral Load
chemical_list: D000914:Antibodies, Viral