title: Early clinical outcomes of implantation of posterior chamber phakic intraocular lens with a central hole (Hole ICL) for moderate to high myopia.
abstract: OBJECTIVE
  To assess the early clinical outcomes of an ICL with a central hole (Hole ICL) implantation for the correction of moderate to high myopia.
  
  
  METHODS
  This study evaluated 20 eyes of 20 patients with spherical equivalents of -7.36 ± 2.13 D (mean ± SD) who underwent Hole ICL implantation. Before surgery and at 1 week and 1, 3 and 6 months after surgery, we assessed the safety, efficacy, predictability, stability and adverse events of the surgery.
  
  
  RESULTS
  Logarithm of the minimum angle of resolution (logMAR) uncorrected visual acuity and logMAR best spectacle-corrected visual acuity were -0.20 ± 0.12 and -0.25 ± 0.06, respectively, 6 months after surgery. The safety and efficacy indices were 1.13 ± 0.24 and 1.03 ± 0.30, respectively. At 6 months, 95%, and 100% eyes were within ± 0.5 and ± 1.0 D of the targeted correction, respectively. Change in manifest refraction from week 1 to month 6 was 0.06 ± 0.28 D. No significant rise in intraocular pressure (including pupillary block) or a secondary cataract occurred in any case during the period of observation.
  
  
  CONCLUSIONS
  Implantation of a newly developed Hole ICL offered good results for all measures of safety, efficacy, predictability and stability for the correction of moderate to high myopic errors, even without peripheral iridectomy, suggesting its viability as a surgical option for the treatment of such eyes.
authors: Department of Ophthalmology, Kitasato University School of Medicine, 1-15-1 Kitasato, Minami-ku, Sagamihara, Kanagawa, 252-0374, Japan. kimiyas@med.kitasato-u.ac.jp
authors: Kimiya
authors: K
authors: Shimizu
authors: Kazutaka
authors: K
authors: Kamiya
authors: Akihito
authors: A
authors: Igarashi
authors: Tetsu
authors: T
authors: Shiratani
mesh_terms: D000328:Adult; D002452:Cell Count; D004728:Endothelium, Corneal / Q000473:pathology; D005260:Female; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology; D019654:Lens Implantation, Intraocular; D008297:Male; D008875:Middle Aged; D047728:Myopia, Degenerative / Q000503:physiopathology / Q000601:surgery*; D054120:Phakic Intraocular Lenses; D011446:Prospective Studies; D011474:Prosthesis Design; D012029:Refraction, Ocular / Q000502:physiology; D016896:Treatment Outcome; D014792:Visual Acuity / Q000502:physiology; D055815:Young Adult