title: Endovascular treatment of symptomatic radiation-induced basilar artery stenosis 25 years after medulloblastoma.
abstract: Intracranial stenosis as late sequela after cerebral radiation therapy for medulloblastoma is an exceptionally rare finding. We report for the first time a case of 31-year-old patient with a history of medulloblastoma 25 years ago and now presenting with radiation-induced high-grade basilar stenosis and recurrent ischemic symptoms despite best medical therapy. The stenosis was treated successfully with angioplasty followed by stenting using a self-expandable microstent. Additionally, MRI revealed multiple cavernomas, illustrating that radiation-induced microbleeds may occur.
authors: University of Nuremberg-Erlangen, Department of Neuroradiology, Erlangen, Germany. philipp.goelitz@uk-erlangen.de
authors: P
authors: P
authors: Gölitz
authors: F
authors: F
authors: Knossalla
authors: S
authors: S
authors: Ott
authors: T
authors: T
authors: Struffert
authors: A
authors: A
authors: Doerfler
mesh_terms: D000328:Adult; D000800:Angioplasty, Balloon; D006801:Humans; D008297:Male; D008527:Medulloblastoma / Q000532:radiotherapy*; D011878:Radiotherapy / Q000009:adverse effects*; D015607:Stents; D016896:Treatment Outcome; D014715:Vertebrobasilar Insufficiency / Q000209:etiology / Q000601:surgery*