title: Hepatocellular carcinoma in a case of Wilson's disease treated with radiofrequency ablation therapy.
abstract: A 37-year-old Japanese man was diagnosed with liver cirrhosis due to Wilson's disease in 2001 and treated with D-penicillamine. Thereafter, he was admitted to our hospital for further examination of a space occupying lesion in the liver. The patient was diagnosed with hepatocellular carcinoma (HCC) (7th segment, 2.5 cm in diameter) in May 2010 and treated with radiofrequency ablation therapy. Biopsy findings from a non-cancerous area revealed a fatty liver, though cirrhotic nodules were not found. Long-term treatment for Wilson's disease may improve hepatic fibrosis, and careful screening for HCC by abdominal imaging is needed in such cases.
authors: Ehime Prefectural Central Hospital, Japan.
authors: Shuntaro
authors: S
authors: Ikegawa
authors: Atsushi
authors: A
authors: Hiraoka
authors: Yukou
authors: Y
authors: Shimizu
authors: Satoshi
authors: S
authors: Hidaka
authors: Nayu
authors: N
authors: Tazuya
authors: Misa
authors: M
authors: Ichiryu
authors: Hiromasa
authors: H
authors: Nakahara
authors: Atsushi
authors: A
authors: Tanabe
authors: Tetsuya
authors: T
authors: Tanihira
authors: Aki
authors: A
authors: Hasebe
authors: Yasunao
authors: Y
authors: Miyamoto
authors: Tomoyuki
authors: T
authors: Ninomiya
authors: Masashi
authors: M
authors: Hirooka
authors: Teru
authors: T
authors: Kumagi
authors: Masanori
authors: M
authors: Abe
authors: Yoichi
authors: Y
authors: Hiasa
authors: Morikazu
authors: M
authors: Onji
authors: Kojiro
authors: K
authors: Michitaka
mesh_terms: D000328:Adult; D006528:Carcinoma, Hepatocellular / Q000175:diagnosis / Q000209:etiology / Q000628:therapy*; D017115:Catheter Ablation / Q000379:methods; D006527:Hepatolenticular Degeneration / Q000150:complications / Q000628:therapy*; D006801:Humans; D008113:Liver Neoplasms / Q000175:diagnosis / Q000209:etiology / Q000628:therapy*; D008297:Male