title: New insight on 2-naphthylmethyl (NAP) ether as a protecting group in carbohydrate synthesis: a divergent approach towards a high-mannose type oligosaccharide library.
abstract: A new method for selective cleavage of 2-naphthylmethyl (NAP) ether utilizing 10-20 molar excess of HF/pyridine in toluene was revealed and strategically applied to a divergent approach towards generation of a high-mannose type oligosaccharide library.
authors: Department of Chemistry, University of Pittsburgh, 219 Parkman Avenue, Pittsburgh, PA 15260, USA.
authors: Yao
authors: Y
authors: Li
authors: Bimalendu
authors: B
authors: Roy
authors: Xinyu
authors: X
authors: Liu
mesh_terms: D004986:Ether / Q000737:chemistry*; D006858:Hydrofluoric Acid / Q000737:chemistry; D008358:Mannose / Q000737:chemistry*; D009281:Naphthalenes / Q000737:chemistry*; D009844:Oligosaccharides / Q000138:chemical synthesis / Q000737:chemistry*; D011725:Pyridines / Q000737:chemistry; D014050:Toluene / Q000737:chemistry
chemical_list: D009281:Naphthalenes; D009844:Oligosaccharides; D011725:Pyridines; D004986:Ether; D014050:Toluene; D008358:Mannose; D006858:Hydrofluoric Acid