title: Effect of alkaline ph on sealing ability of white mineral trioxide aggregate.
abstract: OBJECTIVE
  The aim of this study was to evaluate microleakage of white mineral trioxide aggregate (WMTA) after its exposure to a range of alkaline environments during hydration.
  
  
  METHODS
  Seventy single-rooted teeth were divided into 4 experimental and 2 control groups. All the teeth were instrumented, and their apices were resected. Root-end cavities were filled with WMTA in the experimental groups. In the control groups, root-end cavities were not filled. Root-end fillings were exposed to alkaline environments with pH values of 7.4, 8.4, 9.4, or 10.4 for 3 days. Microleakage was evaluated by bovine serum albumin. Evaluations were carried out at 24-hour intervals for 80 days. Data were analyzed by one-way analysis of variance and a post hoc Tukey test at the 0.05 level of confidence.
  
  
  RESULTS
  The number of days (mean ± standard deviation) needed for color change at pH values of 7.4, 8.4, 9.4, and 10.4 were 78.53 ± 5.68, 80.00 ± 0.00, 68.93 ± 19.00, and 34.46 ± 12.73, respectively. The time needed for leakage to occur was significantly shorter in samples stored at a pH value of 10.4 (P<0.001).
  
  
  CONCLUSIONS
  Within the limits of this study, it can be concluded that pH values greater than 9.4 may jeopardize the sealing ability of WMTA during hydration.
authors: Department of Oral and Maxillofacial Pathology, Dental Faculty, Tabriz University (Medical Sciences), Tabriz, Iran.
authors: Mehrdad
authors: M
authors: Lotfi
authors: Sepideh
authors: S
authors: Vosoughhosseini
authors: Mohammadali
authors: M
authors: Saghiri
authors: Vahid
authors: V
authors: Zand
authors: Hamid Reza
authors: HR
authors: Yavari
authors: Soodabeh
authors: S
authors: Kimyai
authors: Masoumeh
authors: M
authors: Mehdipour
authors: Bahram
authors: B
authors: Ranjkesh
authors: Hadi
authors: H
authors: Mokhtari
authors: Amin
authors: A
authors: Salemmilani
authors: Sirvan
authors: S
authors: Doosti
mesh_terms: D017607:Aluminum Compounds; D017610:Calcium Compounds; D003738:Dental Cements; D003763:Dental Leakage; D004338:Drug Combinations; D006801:Humans; D006863:Hydrogen-Ion Concentration; D066298:In Vitro Techniques; D010087:Oxides; D017640:Silicates
chemical_list: D017607:Aluminum Compounds; D017610:Calcium Compounds; D003738:Dental Cements; D004338:Drug Combinations; D010087:Oxides; D017640:Silicates; C086631:mineral trioxide aggregate