title: Piperazic acid-containing natural products: isolation, biological relevance and total synthesis.
abstract: Since their first discovery in 1959, natural products containing the piperazic acid motif have been isolated from a variety of sources and exhibit diverse biological activity profiles. This review provides information about their isolation and biological activities, and presents an overview of recent total syntheses of these molecules.
authors: Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK.
authors: Alexander J
authors: AJ
authors: Oelke
authors: David J
authors: DJ
authors: France
authors: Tatjana
authors: T
authors: Hofmann
authors: Georg
authors: G
authors: Wuitschik
authors: Steven V
authors: SV
authors: Ley
mesh_terms: D001688:Biological Products / Q000138:chemical synthesis / Q000302:isolation & purification / Q000494:pharmacology; D015394:Molecular Structure; D011724:Pyridazines / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology
chemical_list: D001688:Biological Products; D011724:Pyridazines; C014756:piperazic acid