title: News on ABA transport, protein degradation, and ABFs/WRKYs in ABA signaling.
abstract: The recent identification of abscisic acid (ABA) transporters provides an important insight into the delivery of ABA from the vascular system and its uptake by target cells. A putative connection with PYR/PYL receptors is envisaged, linking ABA uptake and intracellular perception by a fast and efficient mechanism. Downstream signaling of the core pathway involves regulation of ABA-responsive element binding factors (ABFs/AREBs) through phosphorylation, ubiquitination, and sumoylation in the case of ABI5. Several E3 ligases appear to regulate ABA signaling either positively or negatively, although relatively few targets are known yet. ABFs/AREBs are themselves subjected to transcriptional regulation, and some transcription factors (TFs) harboring the WRKY domain (WRKYs) appear to regulate their expression through W-box sequences present in the promoters of ABFs/AREBs.
authors: Instituto de Biologia Molecular y Celular de Plantas, Consejo Superior de Investigaciones Cientificas-Universidad Politecnica de Valencia, Avd de los Naranjos, ES-46022 Valencia, Spain.
authors: Regina
authors: R
authors: Antoni
authors: Lesia
authors: L
authors: Rodriguez
authors: Miguel
authors: M
authors: Gonzalez-Guzman
authors: Gaston A
authors: GA
authors: Pizzio
authors: Pedro L
authors: PL
authors: Rodriguez
mesh_terms: D000040:Abscisic Acid / Q000378:metabolism*; D001692:Biological Transport; D010940:Plant Proteins / Q000378:metabolism*; D010944:Plants / Q000378:metabolism*; D059748:Proteolysis; D015398:Signal Transduction; D014157:Transcription Factors
chemical_list: D010940:Plant Proteins; D014157:Transcription Factors; D000040:Abscisic Acid