title: Synthesis of the proposed structure of phaeosphaeride A.
abstract: The first total synthesis of the proposed structure of phaeosphaeride A has been achieved via six-membered-ring formation by means of an intramolecular vinyl-anion aldol reaction as the key step. This synthesis suggests a revised configurational assignment for phaeosphaeride A.
authors: Discovery Research Laboratories, Kyorin Pharmaceutical Co., Ltd., Shimotsuga-Gun, Tochigi, Japan.
authors: Kenichi
authors: K
authors: Kobayashi
authors: Iwao
authors: I
authors: Okamoto
authors: Nobuyoshi
authors: N
authors: Morita
authors: Tamiko
authors: T
authors: Kiyotani
authors: Osamu
authors: O
authors: Tamura
mesh_terms: D000447:Aldehydes / Q000737:chemistry; D019086:Bridged Bicyclo Compounds, Heterocyclic / Q000138:chemical synthesis*; D005658:Fungi / Q000737:chemistry; D008958:Models, Molecular; D050796:STAT3 Transcription Factor / Q000037:antagonists & inhibitors*
chemical_list: D000447:Aldehydes; D019086:Bridged Bicyclo Compounds, Heterocyclic; D050796:STAT3 Transcription Factor; C520910:phaeosphaeride A; C116609:3-hydroxybutanal