title: Acute aortic occlusion from a Candida fungus ball.
abstract: Fungal arterial infections are well-described entities resulting in direct invasion of the arterial wall or embolic occlusion of small and medium-sized arteries. However, acute occlusion of large vessels such as the aorta by fungal material is exceedingly rare. A 53-year-old woman presented with acute bilateral lower extremity ischemia. She had a history of fungal endocarditis requiring two prosthetic mitral valve replacements; the last episode was 7 months before the current admission. Imaging studies revealed that she had an acute infrarenal aortic occlusion, with evidence of multiple end-organ emboli. After transfemoral thromboembolectomy, perfusion was restored to her lower extremities with minor neurologic sequelae. She ultimately responded to intravenous antifungal agents.
authors: Division of Vascular Surgery, New York Hospital Queens, Flushing, NY 11355, USA.
authors: Alexander I
authors: AI
authors: Kraev
authors: Shah
authors: S
authors: Giashuddin
authors: Vildana
authors: V
authors: Omerovic
authors: Alexander
authors: A
authors: Itskovich
authors: Gregg S
authors: GS
authors: Landis
mesh_terms: D000208:Acute Disease; D000935:Antifungal Agents / Q000008:administration & dosage; D001011:Aorta / Q000382:microbiology*; D001027:Aortography / Q000379:methods; D001157:Arterial Occlusive Diseases / Q000000981:diagnostic imaging / Q000382:microbiology* / Q000628:therapy; D002176:Candida albicans / Q000302:isolation & purification / Q000472:pathogenicity*; D002177:Candidiasis / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D017128:Embolectomy; D004617:Embolism / Q000000981:diagnostic imaging / Q000382:microbiology* / Q000628:therapy; D004696:Endocarditis / Q000382:microbiology* / Q000628:therapy; D005260:Female; D019918:Heart Valve Prosthesis Implantation; D006801:Humans; D007511:Ischemia / Q000000981:diagnostic imaging / Q000382:microbiology* / Q000628:therapy; D035002:Lower Extremity / Q000098:blood supply*; D008875:Middle Aged; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D000935:Antifungal Agents