title: Automatic sleep scoring: a search for an optimal combination of measures.
abstract: OBJECTIVE
  The objective of this study is to find the best set of characteristics of polysomnographic signals for the automatic classification of sleep stages.
  
  
  METHODS
  A selection was made from 74 measures, including linear spectral measures, interdependency measures, and nonlinear measures of complexity that were computed for the all-night polysomnographic recordings of 20 healthy subjects. The adopted multidimensional analysis involved quadratic discriminant analysis, forward selection procedure, and selection by the best subset procedure. Two situations were considered: the use of four polysomnographic signals (EEG, EMG, EOG, and ECG) and the use of the EEG alone.
  
  
  RESULTS
  For the given database, the best automatic sleep classifier achieved approximately an 81% agreement with the hypnograms of experts. The classifier was based on the next 14 features of polysomnographic signals: the ratio of powers in the beta and delta frequency range (EEG, channel C3), the fractal exponent (EMG), the variance (EOG), the absolute power in the sigma 1 band (EEG, C3), the relative power in the delta 2 band (EEG, O2), theta/gamma (EEG, C3), theta/alpha (EEG, O1), sigma/gamma (EEG, C4), the coherence in the delta 1 band (EEG, O1-O2), the entropy (EMG), the absolute theta 2 (EEG, Fp1), theta/alpha (EEG, Fp1), the sigma 2 coherence (EEG, O1-C3), and the zero-crossing rate (ECG); however, even with only four features, we could perform sleep scoring with a 74% accuracy, which is comparable to the inter-rater agreement between two independent specialists.
  
  
  CONCLUSIONS
  We have shown that 4-14 carefully selected polysomnographic features were sufficient for successful sleep scoring. The efficiency of the corresponding automatic classifiers was verified and conclusively demonstrated on all-night recordings from healthy adults.
authors: Institute of Measurement Science, Slovak Academy of Sciences, Bratislava, Slovak Republic. krakovska@savba.sk
authors: Anna
authors: A
authors: Krakovská
authors: Kristína
authors: K
authors: Mezeiová
mesh_terms: D000465:Algorithms; D004569:Electroencephalography / Q000379:methods*; D004576:Electromyography / Q000379:methods; D017709:Fractals; D006801:Humans; D012815:Signal Processing, Computer-Assisted; D012890:Sleep / Q000502:physiology*; D012894:Sleep Stages / Q000502:physiology