title: Case of diabetic scleredema: diagnostic value of magnetic resonance imaging.
abstract: We report the case of a patient with a 20-year history of diabetes mellitus type 2 who developed sclerotic skin lesions on his neck and upper back. Physical and histological findings were compatible with diabetic scleredema. T(2)-weighted magnetic resonance imaging (MRI) revealed diffuse thickening of the dermis and subcutaneous tissue, with hyperintense signals. The MRI findings in the dermis corresponded with the accumulation of collagen tissue with deposition of glycosaminoglycans.
authors: Kyushu Central Hospital, Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan. y-kuri@dermatol.med.kyushu-u.ac.jp
authors: Yuichi
authors: Y
authors: Kurihara
authors: Hisashi
authors: H
authors: Kokuba
authors: Masutaka
authors: M
authors: Furue
mesh_terms: D003094:Collagen / Q000378:metabolism; D048909:Diabetes Complications / Q000175:diagnosis* / Q000378:metabolism; D003924:Diabetes Mellitus, Type 2 / Q000150:complications; D006025:Glycosaminoglycans / Q000378:metabolism; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D012592:Scleredema Adultorum / Q000175:diagnosis* / Q000378:metabolism; D012867:Skin / Q000378:metabolism / Q000473:pathology; D040521:Subcutaneous Tissue / Q000378:metabolism / Q000473:pathology
chemical_list: D006025:Glycosaminoglycans; D003094:Collagen