title: High prevalence of spirometric abnormalities in patients with type 1 diabetes mellitus.
abstract: OBJECTIVE
  To document abnormalities on spirometry in patients with type1 diabetes mellitus (DM) and to study the determinants of these.
  
  
  METHODS
  Thirty nine patients attending the type 1 DM clinic underwent spirometry. The absolute FEV1 and FVC were compared with the predicted ones and expressed as a percentage of the predicted. Additional information collected included gender, age, weight, height and the latest glycated hemoglobin. Data were presented as mean±SD.χ2 test was used to study differences in proportions and Pearson's coefficient was calculated for correlations.
  
  
  RESULTS
  Twenty patients (51.2%) had pulmonary function abnormalities, of which 17 patients had a restrictive pattern on spirometry and 3 had an obstructive pattern. Of all the patients, 45.8% were stunted, i.e. had the height SDS <-2 SD while 25.7% were extremely stunted (height SDS < -3). Sevenof 9 (77.8%) patients with extreme stunting (Ht SDS <-3) had restrictive ventilatory disturbances, whereas only 8 of 26 (30.7%) persons with Ht SDS above -3 had the same (p <0.05).
  
  
  CONCLUSIONS
  Spirometric abnormalities are common in type 1 DM and stunting is a significant determinant of the same.
authors: Department of Endocrinology, Sri Venkateswara Institute of Medicine Sciences, Tirupati, Andhra Pradesh, India.
authors: Vaikkakara
authors: V
authors: Suresh
authors: Amaresh
authors: A
authors: Reddy
authors: Alladi
authors: A
authors: Mohan
authors: Gadekal
authors: G
authors: Rajgopal
authors: Potham
authors: P
authors: Satish
authors: Chittari
authors: C
authors: Harinarayan
authors: Parameswari
authors: P
authors: Rekha
authors: Alok
authors: A
authors: Sachan
mesh_terms: D000293:Adolescent; D000328:Adult; D017668:Age of Onset; D002648:Child; D003922:Diabetes Mellitus, Type 1 / Q000150:complications* / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008171:Lung Diseases / Q000150:complications / Q000175:diagnosis; D008297:Male; D015995:Prevalence; D013147:Spirometry / Q000706:statistics & numerical data*; D055815:Young Adult