title: Disseminated Mycobacterium tuberculosis in an infant with AIDS.
abstract: Disseminated Mycobacterium tuberculosis with involvement of liver, spleen, and bone marrow is a nonspecific and rare complication in human immunodeficiency virus (HIV) infected infants. Here, we report a six month old girl with fever, recurrent infections, bilateral axilary lymphadenitis, hepatomegaly, huge splenomegaly, and failure to thrive per the Center for Disease Control category of C for AIDS. The infant and her mother had positive enzyme immunoassay (EIA) and Western blot. HIV DNA PCR test of the infant was positive with subtype A (A1) in genotyping. A positive bone marrow aspirate staining for acid fast bacilli and PCR test on culture revealed Mycobacterium tuberculosis.
authors: Department of Pediatrics, Shiraz University of Medical Sciences, Shiraz, Iran. dr_masoumiasl@yahoo.com
authors: Hossein
authors: H
authors: Masoumi Asl
authors: Abdolvahab
authors: A
authors: Alborzi
authors: Esmaeel
authors: E
authors: Sadeghi
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D000163:Acquired Immunodeficiency Syndrome / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D060085:Coinfection / Q000175:diagnosis; D005260:Female; D006801:Humans; D007223:Infant; D009169:Mycobacterium tuberculosis; D014376:Tuberculosis / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology