title: Impact of coronary artery bypass surgery on ischemic mitral regurgitation.
abstract: BACKGROUND
  To determine the course of ischemic mitral regurgitation (IMR) after coronary artery bypass grafting (CABG), and evaluate preoperative factors which predict the development of the severity of IMR after CABG.
  
  
  METHODS
  Between 1992-2005, 1995 patients underwent CABG and 170 of them had IMR. Data of 131 patients were retrospectively analyzed and living patients (n = 112) had a clinical follow-up visit. The mean follow-up time was 6.5 years.
  
  
  RESULTS
  At the time of CABG, 66% of the 131 cases analyzed had mild, 31% had moderate, and 3% had severe IMR. At the time of follow-up, 52% of patients had either no IMR or mild IMR, 27% had moderate IMR, 6% had severe IMR and 15% suffered from cardiac related death. During follow-up IMR grade reduced in 25% of study patients. None of the patient had re-operation due to the mitral regurgitation. Multivariate analysis showed that left ventricular ejection fraction (LVEF) was an independent predictor of good prognosis (O.R. 1.4, 95% C.I. 1.15-1.83/ 10% increase of LVEF, p = 0.02).
  
  
  CONCLUSIONS
  Half of the patients, who have IMR at the time of CABG, have no IMR or only mild IMR postoperatively. Good LVEF adds to the probability that CABG only can reduce IMR.
authors: Department of Internal Medicine, North Karelia Hospital, Joensuu, Finland. juha.mustonen@pkssk.fi
authors: J
authors: J
authors: Mustonen
authors: H
authors: H
authors: Suurmunne
authors: J
authors: J
authors: Kouri
authors: O
authors: O
authors: Pitkänen
authors: T
authors: T
authors: Hakala
mesh_terms: D000368:Aged; D001026:Coronary Artery Bypass; D003324:Coronary Artery Disease / Q000601:surgery; D018450:Disease Progression; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D008944:Mitral Valve Insufficiency / Q000150:complications* / Q000473:pathology; D017202:Myocardial Ischemia / Q000150:complications* / Q000473:pathology / Q000601:surgery*; D011379:Prognosis; D012086:Reoperation; D012189:Retrospective Studies; D012720:Severity of Illness Index; D016896:Treatment Outcome