title: Low-density lipoprotein density determination by electric conductivity.
abstract: The predominance of small dense low-density lipoprotein (LDL) particles is associated with an increased risk of coronary heart disease. A simple but precise method has been developed, based on electrical conductivity of an isopycnic gradient of KBr, to obtain density values of human LDL fraction. The results obtained can distinguish LDL density populations and their subfractions from different patients. These data were corroborated by Fourier transform infrared spectroscopy (FTIR) (structure) and light-scattering analyses (size).
authors: Department of Biochemistry and Molecular Biology, Faculty of Science and Technology, University of the Basque Country, 48080 Bilbao, Spain.
authors: José A
authors: JA
authors: Fernández-Higuero
authors: Ana M
authors: AM
authors: Salvador
authors: José L R
authors: JL
authors: Arrondo
authors: José Carlos G
authors: JC
authors: Milicua
mesh_terms: D001965:Bromides / Q000737:chemistry; D003327:Coronary Disease / Q000175:diagnosis*; D004553:Electric Conductivity; D006801:Humans; D008077:Lipoproteins, LDL / Q000097:blood*; D017680:Potassium Compounds / Q000737:chemistry; D017550:Spectroscopy, Fourier Transform Infrared
chemical_list: D001965:Bromides; D008077:Lipoproteins, LDL; D017680:Potassium Compounds; C039004:potassium bromide