title: Efficient synthesis of β-chlorovinylketones from acetylene in chloroaluminate ionic liquids.
abstract: A method for the Friedel-Crafts-type insertion reaction of acetylene with acid chlorides in chloroaluminate ionic liquids is presented. The use of ionic liquids not only serves to avoid the use of carbon tetrachloride or 1,2-dichloroethane but also suppresses side reactions, notably the polymerization of acetylene, which occurs in these chlorinated solvents. Consequently, the products can be isolated using a simpler purification procedure, giving a range of aromatic and aliphatic β-chlorovinyl ketones in high yield and purity.
authors: Institut des Sciences et Ingénierie Chimiques, Ecole Polytechnique Fédérale de Lausanne (EPFL), CH-1015 Lausanne, Switzerland.
authors: Dennis J M
authors: DJ
authors: Snelders
authors: Paul J
authors: PJ
authors: Dyson
mesh_terms: D000114:Acetylene / Q000737:chemistry*; D000535:Aluminum / Q000737:chemistry*; D002713:Chlorine / Q000737:chemistry*; D052578:Ionic Liquids / Q000737:chemistry*; D007659:Ketones / Q000138:chemical synthesis*; D015394:Molecular Structure; D014753:Vinyl Compounds / Q000138:chemical synthesis*
chemical_list: D052578:Ionic Liquids; D007659:Ketones; D014753:Vinyl Compounds; D002713:Chlorine; D000535:Aluminum; D000114:Acetylene