title: Central venous catheter-related blood stream infections in children undergoing hematopoietic stem cell transplant for primary immunodeficiency and other nonmalignant disorders.
abstract: A single-center experience of catheter-related blood stream infections in children undergoing hematopoietic stem cell transplant for primary immunodeficiency is described. The rate of definite central venous catheter infections was 5.31/1000 line days. Staphylococcus epidermidis was the most commonly identified organism. Teicoplanin resistance occurred in 17% of S. epidermidis infections. The central catheter was removed in 21% of infections.
authors: Institute of Cellular Medicine, Newcastle University, Newcastle, United Kingdom. theresa.cole@ncl.ac.uk
authors: Theresa S
authors: TS
authors: Cole
authors: Elizabeth
authors: E
authors: Rogerson
authors: Jennifer
authors: J
authors: Collins
authors: Angela
authors: A
authors: Galloway
authors: Julia
authors: J
authors: Clark
mesh_terms: D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D016470:Bacteremia / Q000188:drug therapy / Q000209:etiology* / Q000382:microbiology; D055499:Catheter-Related Infections / Q000188:drug therapy / Q000209:etiology* / Q000382:microbiology; D002405:Catheterization, Central Venous / Q000009:adverse effects*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006090:Gram-Negative Bacteria / Q000302:isolation & purification; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D007153:Immunologic Deficiency Syndromes / Q000382:microbiology / Q000601:surgery / Q000628:therapy*; D007223:Infant; D008297:Male; D012189:Retrospective Studies; D013212:Staphylococcus epidermidis / Q000302:isolation & purification
chemical_list: D000900:Anti-Bacterial Agents; D000935:Antifungal Agents