title: [Assessment of thromboplastins according to the WHO guidelines and the results of external quality control].
abstract: The study was undertaken to assess commercial thromboplastins for compliance to the WHO guidelines and to substantiate the validity of the results of a prothrombin test carried out using these thromboplastins. The test thromboplastins were shown to meet the WHO guidelines for assessment of thromboplastins. Over 5-8 years of the authors'participation in two external quality control programs (Federal External Quality Control System, Russia; 72 trials; NEQAS, United Kingdom; 60 trials), the international normalized ratio derived through the use of assessed thromboplastins did not differ from that established due to the interlaboratory consensus value of both external quality control systems. It is concluded that correct thromboplastin assessment provide accurate results of determination of prothrombin time.
authors: A L
authors: AL
authors: Berkovskiĭ
authors: E V
authors: EV
authors: Sergeeva
authors: N D
authors: ND
authors: Kachalova
authors: I D
authors: ID
authors: Gurvits
authors: A V
authors: AV
authors: Suvorov
authors: I S
authors: IS
authors: Ul'ianova
authors: Iu G
authors: IuG
authors: Ivanov
authors: A A
authors: AA
authors: Kozlov
mesh_terms: D001778:Blood Coagulation Disorders / Q000175:diagnosis* / Q000453:epidemiology; D019983:Guideline Adherence; D006801:Humans; D019934:International Normalized Ratio; D017410:Practice Guidelines as Topic; D011517:Prothrombin Time / Q000379:methods / Q000592:standards*; D011785:Quality Assurance, Health Care; D011786:Quality Control; D015203:Reproducibility of Results; D012426:Russia; D013925:Thromboplastin; D014944:World Health Organization
chemical_list: D013925:Thromboplastin