title: A case of lymphoplasmacyte-rich meningioma of the jugular foramen.
abstract: Lymphoplasmacyte-rich meningioma (LPRM), the most rare variant of meningiomas, features extensive lymphoplasmacytic infiltrates. Although the jugular foramen (JF) is occasionally involved by several types of tumor, such as paragangliomas and schwannomas, meningioma in the JF is an infrequent disease. Here we present an extremely rare case of LPRM found in the JF. A 55-year-old woman complained of paresis in her right eyelid and palsy in the right side of her lip. Hoarseness and dysphagia also occurred in the following month. Radiologic examinations disclosed a mass lesion in the right JF, and the tumor was operatively removed. Microscopically, the tumor was composed of extensive lymphoplasmacytic infiltration with mild vascular proliferation and scattered sheets of epithelioid cells with plump cytoplasm. Although the obvious whorl formation or psammoma bodies were not observed, by immunochemistry the epithelioid cells were positive for epithelial membrane antigen and also progesterone receptor, indicating a meningothelial cell origin. Considering the histological and radiologic findings, we finally diagnosed the case as LPRM, making this the second reported case of LPRM in the JF.
authors: Laboratory of Cancer Research, Department of Pathology, Sapporo, Japan.
authors: Hiromi
authors: H
authors: Kanno
authors: Hiroshi
authors: H
authors: Nishihara
authors: Keiji
authors: K
authors: Hara
authors: Yoshimaru
authors: Y
authors: Ozaki
authors: Tamio
authors: T
authors: Itoh
authors: Taichi
authors: T
authors: Kimura
authors: Mishie
authors: M
authors: Tanino
authors: Shinya
authors: S
authors: Tanaka
mesh_terms: D005260:Female; D006801:Humans; D008214:Lymphocytes / Q000473:pathology*; D008577:Meningeal Neoplasms / Q000473:pathology* / Q000601:surgery; D008579:Meningioma / Q000473:pathology* / Q000601:surgery; D008875:Middle Aged; D010950:Plasma Cells / Q000473:pathology*