title: Gastric cancer in the reconstructed gastric tube after radical esophagectomy: a single-center experience.
abstract: OBJECTIVE
  Metachronous gastric carcinoma arising in a gastric tube used for esophageal reconstruction has been occasionally encountered in long-term survivors of esophageal cancer. This study investigated 10 cases of gastric tube cancer in order to clarify the characteristics and the outcome of these patients.
  
  
  METHODS
  Four hundred and seventy-one patients underwent a radical esophagectomy at Kyushu University Hospital between 1989 and 2003. There were 10 cases of gastric tube cancer after an esophagectomy.
  
  
  RESULTS
  The interval between the esophagectomy and the development of the gastric tube cancer ranged from 1.1 to 7 years. There was no peak for the incidence of gastric tube cancer. In 6 of 10 cases of gastric tube cancer, endoscopic or surgical resection were performed for the treatment; however, chemotherapy was administered to the other 4 cases for several reasons. The prognosis of patients who underwent resection was better than that of the other patients.
  
  
  CONCLUSIONS
  Frequent endoscopic examinations are therefore important even several years after performing an esophagectomy, since the risk of gastric tube cancer is higher than the risk of a recurrence of esophageal cancer several years after an esophagectomy. Only an early diagnosis permits a less invasive and appropriate approach for the treatment of gastric tube cancer.
authors: Department of Gastroenterological Surgery, National Kyushu Cancer Center, 3-1-1 Notame, Minami-ku, Fukuoka, 811-1395, Japan.
authors: Eiji
authors: E
authors: Oki
authors: Masaru
authors: M
authors: Morita
authors: Yasushi
authors: Y
authors: Toh
authors: Yasue
authors: Y
authors: Kimura
authors: Kippei
authors: K
authors: Ohgaki
authors: Noriaki
authors: N
authors: Sadanaga
authors: Akinori
authors: A
authors: Egashira
authors: Yoshihiro
authors: Y
authors: Kakeji
authors: Shunichi
authors: S
authors: Tsujitani
authors: Yoshihiko
authors: Y
authors: Maehara
mesh_terms: D000368:Aged; D004938:Esophageal Neoplasms / Q000401:mortality / Q000601:surgery*; D016629:Esophagectomy / Q000009:adverse effects* / Q000379:methods; D005260:Female; D006801:Humans; D015994:Incidence; D007564:Japan; D008297:Male; D008875:Middle Aged; D011184:Postoperative Period; D011379:Prognosis; D012307:Risk Factors; D013274:Stomach Neoplasms / Q000209:etiology* / Q000401:mortality / Q000473:pathology; D016019:Survival Analysis; D013997:Time Factors; D016896:Treatment Outcome