title: Stereotactic aspiration and thrombolysis of spontaneous intracerebellar hemorrhage.
abstract: BACKGROUND
  Spontaneous intracerebellar hemorrhage (SCH) accounts for 10% of intracerebral hemorrhages. Up to now stereotactic aspiration and thrombolysis of SCH was less reported. The aim of this study was to assess the effect and feasibility of the method, and to refine the clinical protocol.
  
  
  METHODS
  Eighteen patients with SCH were treated by stereotactic aspiration and thrombolysis and reviewed in this report. The 3-mm axial stereotactic computed tomography slices throughout the hematoma were obtained. Those images were then transferred to the workstation. The trajectory of catheter was designed to go through the main axis of the hematoma. Under local anesthesia a catheter was directed stereotactically into the hematoma through a burr hole. Hematoma thrombolysis and clot drainage was followed by instillation of urokinase (10,000 U) every 12 hours. The catheter was removed when the majority of hematoma was evacuated.
  
  
  RESULTS
  Initial SCH volume was reduced by an average of 86% and the average final hematoma volume was 2.8 ml. At 3-month follow-up, 13 patients (72%) had achieved good recovery. At 6-month follow-up, 12 patients (67%) had achieved good recovery.
  
  
  CONCLUSIONS
  Stereotactic aspiration and thrombolysis of SCH was a simple, feasible and effective method to treat moderate and some benign SCH that less respond to medical treatment.
authors: Precision Engineering Centre of Harbin Institute of Technology, Harbin, Heilongjiang 150001, China.
authors: Li
authors: L
authors: Liu
authors: Hong
authors: H
authors: Shen
authors: Fan
authors: F
authors: Zhang
authors: Jing-He
authors: JH
authors: Wang
authors: Tao
authors: T
authors: Sun
authors: Zhi-Guo
authors: ZG
authors: Lin
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002543:Cerebral Hemorrhage / Q000188:drug therapy* / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013238:Stereotaxic Techniques; D013396:Suction; D015912:Thrombolytic Therapy / Q000379:methods*; D014568:Urokinase-Type Plasminogen Activator / Q000627:therapeutic use
chemical_list: D014568:Urokinase-Type Plasminogen Activator