title: Analysis and modification of surfaces using molecular ions in the ambient environment.
abstract: The analysis and modification of surfaces in their native conditions can be performed using new mass spectrometric methods. Ambient ionization sources, including desorption electrospray ionization (DESI), have been implemented for the rapid analysis of unmodified biological surfaces including whole plant material, tissue sections, algae, and bacterial colonies. Recent advances have shown promise for in vivo and high-throughput clinical analysis. Additionally, the recent development of ambient ion soft landing (SL) allows polyatomic ions to be deposited onto surfaces in open air. Ambient SL offers speed, control, and flexibility for surface reactions and modification.
authors: Department of Chemistry, Purdue University, 560 Oval Drive, West Lafayette, IN 47907, USA.
authors: Ryan D
authors: RD
authors: Espy
authors: Abraham
authors: A
authors: Badu-Tawiah
authors: R Graham
authors: RG
authors: Cooks
mesh_terms: D000818:Animals; D001274:Atmospheric Pressure; D001419:Bacteria; D000460:Chlorophyta; D057166:High-Throughput Screening Assays; D006801:Humans; D007477:Ions / Q000737:chemistry*; D051379:Mice; D057054:Molecular Imaging / Q000295:instrumentation* / Q000379:methods*; D010944:Plants; D021241:Spectrometry, Mass, Electrospray Ionization / Q000295:instrumentation / Q000379:methods*; D055672:Static Electricity; D013499:Surface Properties; D013696:Temperature
chemical_list: D007477:Ions