title: Saccharomyces cerevisiae oesophagitis in a patient with oesophageal carcinoma.
abstract: Saccharomyces species are emerging opportunistic fungal pathogens that can cause bloodstream infections in humans. These infections have often been associated with the ingestion of probiotics. Saccharomyces oesophagitis is a rare condition which has been described so far in only two publications. Here we report the case of a patient who was diagnosed with Saccharomyces oesophagitis. The clinical picture was indistinguishable from that of Candida oesophagitis. The Saccharomyces isolate was shown to be susceptible to fluconazole by both CLSI M27-A and disk diffusion methods. In contrast to cases of fungaemia, Saccharomyces oesophagitis does not seem to follow probiotic use. Due to the potential for antifungal resistance among emerging fungal pathogens, proper mycological identification at the species level is essential.
authors: Pulmonary Sciences, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil. dimaskliemann@gmail.com
authors: Dimas Alexandre
authors: DA
authors: Kliemann
authors: Vicente Sperb
authors: VS
authors: Antonello
authors: Luis Carlos
authors: LC
authors: Severo
authors: Alessandro Comarú
authors: AC
authors: Pasqualotto
mesh_terms: D000935:Antifungal Agents / Q000494:pharmacology; D002277:Carcinoma / Q000150:complications* / Q000175:diagnosis*; D016145:Endoscopy, Digestive System; D004938:Esophageal Neoplasms / Q000150:complications* / Q000175:diagnosis*; D004941:Esophagitis / Q000175:diagnosis* / Q000382:microbiology* / Q000473:pathology; D015725:Fluconazole / Q000494:pharmacology; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D012441:Saccharomyces cerevisiae / Q000187:drug effects / Q000302:isolation & purification*
chemical_list: D000935:Antifungal Agents; D015725:Fluconazole