title: Low-grade appendiceal mucinous neoplasm with disseminated peritoneal adenomucinosis involving the uterus, mimicking primary mucinous endometrial adenocarcinoma: a case report.
abstract: We present a patient with a low-grade appendiceal mucinous neoplasm, resulting in disseminated peritoneal adenomucinosis (pseudomyxoma peritonei) with uterine involvement, and mimicking primary mucinous endometrial adenocarcinoma. On immunohistochemistry, neoplastic glands were cytokeratin 7-negative and cytokeratin 20-positive, indicating a gastrointestinal origin rather than a primary ovarian mucinous neoplasm. A diagnosis of uterine metastasis of appendiceal origin was made, based on the constellation of clinicopathological findings, that is, preceding appendiceal neoplasm, peritoneal involvement, absence of coexisting prototypical endometrioid adenocarcinoma or endometrial hyperplasia. The patient underwent hysterectomy and there was no evidence of disease progression at the 12-month follow up. This suggested the indolent nature of this particular neoplasm, despite its advanced stage.
authors: Department of Obstetrics and Gynecology, Mie Prefectural General Medical Center, Yokkaichi, Mie, Japan. htanaka1576@excite.co.jp
authors: Hirohiko
authors: H
authors: Tanaka
authors: Takumi
authors: T
authors: Kobayashi
authors: Kayo
authors: K
authors: Yoshida
authors: Tetsuo
authors: T
authors: Asakura
authors: Haruki
authors: H
authors: Taniguchi
authors: Yoshiki
authors: Y
authors: Mikami
mesh_terms: D002288:Adenocarcinoma, Mucinous / Q000473:pathology*; D001063:Appendiceal Neoplasms / Q000473:pathology*; D003937:Diagnosis, Differential; D016889:Endometrial Neoplasms / Q000473:pathology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D010534:Peritoneal Neoplasms / Q000473:pathology*; D011553:Pseudomyxoma Peritonei / Q000473:pathology*; D014599:Uterus / Q000473:pathology*