title: Neutropenia in infants with hemolytic disease of the newborn.
abstract: BACKGROUND
  This study examined the incidence, outcome and risk factors of neutropenia in infants with hemolytic disease of the newborn (HDN).
  
  
  METHODS
  A retrospective chart review was performed on infants with HDN.
  
  
  RESULTS
  Of 69 evaluable infants, 45% developed neutropenia. Only one infectious complication was recorded. In most instances the neutropenia resolved spontaneously, but in seven infants it persisted for a median of 397 days. Males were at higher risk for developing neutropenia, but severity of HDN, antibody specificity, or therapy were not significant risk factors.
  
  
  CONCLUSIONS
  Neutropenia is a common feature of HDN, regardless of severity of disease, treatment received, or antibody specificity.
authors: Department of Pediatrics, Hospital for Sick Children, Toronto, Ontario, Canada.
authors: Esther
authors: E
authors: Blanco
authors: Donna L
authors: DL
authors: Johnston
mesh_terms: D004899:Erythroblastosis, Fetal / Q000097:blood*; D005260:Female; D006801:Humans; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D009503:Neutropenia / Q000453:epidemiology* / Q000209:etiology*; D012189:Retrospective Studies; D012307:Risk Factors