title: Reversible acetylation of metabolic enzymes celebration: SIRT2 and p300 join the party.
abstract: Compelling evidence suggests that metabolic pathways are coordinated through reversible acetylation of metabolic enzymes in response to nutrient availability. In this issue of Molecular Cell, Jiang et al. (2011) show that the rate-limiting enzyme in gluconeogenesis, phosphoenolpyruvate carboxykinase 1, is regulated through reversible acetylation by SIRT2 and p300.
authors: Department of Nutritional Sciences and Toxicology, University of California, Berkeley, Berkeley, CA 94720, USA.
authors: Jiyung
authors: J
authors: Shin
authors: Dan
authors: D
authors: Zhang
authors: Danica
authors: D
authors: Chen