title: Prevalence and effect on health-related quality of life of overactive bladder in older americans: results from the epidemiology of lower urinary tract symptoms study.
abstract: OBJECTIVE
  To evaluate the prevalence and effect of overactive bladder (OAB) on healthcare-seeking behavior, mental health, and generic and condition-specific health-related quality of life (HRQL) in older adults.
  
  
  METHODS
  Secondary analysis of the U.S. sample of the Epidemiology of Lower Urinary Tract Symptoms (EpiLUTS) study-a population-based, cross-sectional, Internet-based survey.
  
  
  METHODS
  Community.
  
  
  METHODS
  Two thousand four hundred eighty-five men and 2,877 women aged 65 and older.
  
  
  METHODS
  Prevalence and effect on HRQL of urinary symptoms, including OAB. OAB was defined as the presence of urinary urgency and/or urinary urgency incontinence. Descriptive analyses and subgroup comparisons were conducted to evaluate the prevalence of OAB in men and women aged 65 and older and the effect of OAB on various aspects of HRQL.
  
  
  RESULTS
  The survey response rate was 46.9% of men and 61.0% of women. Prevalence rates of OAB at least "sometimes" were 40.4% in men and 46.9% in women. OAB was associated with significant impairments across all domains of patient-reported outcomes, including general HRQL (Medical Outcomes Study 12-item Short-Form Survey), ratings of anxiety and depression (Hospital Anxiety and Depression Scale), and urinary condition-specific outcomes (Overactive Bladder Questionnaire Short Form and Patient Perception of Bladder Condition) (P<.001).
  
  
  CONCLUSIONS
  OAB is common in older adults in the United States and is associated with substantial impairment in mental health and HRQL, but rates of treatment seeking behavior are low. Older patients should be assessed for OAB.
authors: United BioSource Corporation, Bethesda, Maryland, USA. Chris.Sexton@unitedbiosource.com
authors: Chris C
authors: CC
authors: Sexton
authors: Karin S
authors: KS
authors: Coyne
authors: Christine
authors: C
authors: Thompson
authors: Tamara
authors: T
authors: Bavendam
authors: Chieh-I
authors: CI
authors: Chen
authors: Alayne
authors: A
authors: Markland
mesh_terms: D000368:Aged; D003430:Cross-Sectional Studies; D005260:Female; D006306:Health Surveys; D006801:Humans; D020407:Internet; D008297:Male; D053158:Nocturia / Q000453:epidemiology / Q000523:psychology; D011788:Quality of Life / Q000523:psychology*; D014481:United States; D053201:Urinary Bladder, Overactive / Q000453:epidemiology* / Q000523:psychology* / Q000628:therapy; D053202:Urinary Incontinence, Urge / Q000453:epidemiology / Q000523:psychology / Q000628:therapy