title: [Successful chemotherapy of carcinomatosis of the bone marrow with disseminated intravascular coagulation from a rectal carcinoma found by eosinophilia].
abstract: A 71-year-old man with eosinophilia was given a diagnosis of poorly differentiated adenocarcinoma of the rectum. Further examination showed that it had invaded the bone marrow. He had disseminated intravascular coagulation (DIC) from disseminated carcinomatosis of the bone marrow after colostomy. Chemotherapy (mFOLFOX6) was successful and his eosinophil count, DIC score and tumor markers normalized. We were able to continue chemotherapy after 5 months from the outbreak of disseminated carcinomatosis of the bone marrow. It is said that disseminated carcinomatosis of the bone marrow has a poor prognosis, but we were able to obtain a good response in this case by chemotherapy.
authors: Department of Gastroenterology, Sapporo Hokuyu Hospital.
authors: Asumi
authors: A
authors: Higashiyama
authors: Mineo
authors: M
authors: Kudo
authors: Tomokazu
authors: T
authors: Nagasako
authors: Naoyuki
authors: N
authors: Kawamura
authors: Satoshi
authors: S
authors: Abiko
authors: Yoichi
authors: Y
authors: Yamamoto
authors: Masatoshi
authors: M
authors: Takano
authors: Junichi
authors: J
authors: Gotoh
authors: Tohru
authors: T
authors: Tamaki
authors: Jun-Ichi
authors: J
authors: Meguro
authors: Motoki
authors: M
authors: Yonekawa
authors: Akio
authors: A
authors: Kawamura
authors: Mishie
authors: M
authors: Tanino
mesh_terms: D000230:Adenocarcinoma / Q000150:complications* / Q000175:diagnosis; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D019046:Bone Marrow Neoplasms / Q000188:drug therapy*; D002277:Carcinoma / Q000188:drug therapy*; D004211:Disseminated Intravascular Coagulation / Q000188:drug therapy / Q000209:etiology*; D004802:Eosinophilia / Q000150:complications*; D005472:Fluorouracil / Q000627:therapeutic use; D006801:Humans; D002955:Leucovorin / Q000627:therapeutic use; D008297:Male; D009944:Organoplatinum Compounds / Q000627:therapeutic use; D012004:Rectal Neoplasms / Q000150:complications* / Q000175:diagnosis
chemical_list: D009944:Organoplatinum Compounds; D002955:Leucovorin; D005472:Fluorouracil