title: Primary pigmented nodular adrenocortical disease.
abstract: Primary pigmented nodular adrenocortical disease (PPNAD) is a rare adrenal tumour causing corticotrophin-independent Cushing's syndrome. It occurs mainly in children and young adults. The histological examination is characterised by small pigmented micronodules on the adrenal cortex. The diagnosis is most often seen in patients with Carney Complex, but it can also occur in isolation. We report a case of Carney Complex that was referred for adrenalectomy. The procedure was uneventful and the patient was well at discharge. The adrenal pathology showed numerous black nodules measuring less than 2mm in diameter. This feature was pathognomonic of primary pigmented nodular adrenocortical disease.
authors: International Islamic University of Malaysia/Hospital Tengku Ampuan Afzan, Kulliyyah Of Medicine, Jalan Hospital, Pahang, Malaysia. harrisngow@gmail.com
authors: Harris Abdullah
authors: HA
authors: Ngow
authors: Wan Mohd Nowalid Wan
authors: WM
authors: Khairina
mesh_terms: D000306:Adrenal Cortex Neoplasms / Q000473:pathology* / Q000601:surgery*; D000315:Adrenalectomy; D000328:Adult; D056733:Carney Complex / Q000175:diagnosis*; D005260:Female; D006801:Humans