title: Heavy prenatal alcohol exposure and risk of stillbirth and preterm delivery.
abstract: We prospectively identified 96 women consuming at least 4 drinks/day during pregnancy by screening 9628 pregnant women. In these women with heavy prenatal alcohol use, there were three stillbirths and one preterm delivery; 98 matched nondrinking women had no stillbirths and two preterm births. Preterm rates did not differ significantly. The stillbirth rate was higher in the exposed group (p = 0.06). Additional investigation showed the stillbirth rate in the exposed population (3.1%) was significantly higher (p = 0.019) than the reported Chilean population rate (0.45%). Our data suggest that heavy alcohol consumption may increase the risk for stillbirth but not preterm delivery.
authors: Division of Epidemiology, Statistics and Prevention Research, Eunice Kennedy Shriver National Institute for Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA.
authors: Joshua
authors: J
authors: Cornman-Homonoff
authors: Devon
authors: D
authors: Kuehn
authors: Sofía
authors: S
authors: Aros
authors: Tonia C
authors: TC
authors: Carter
authors: Mary R
authors: MR
authors: Conley
authors: James
authors: J
authors: Troendle
authors: Fernando
authors: F
authors: Cassorla
authors: James L
authors: JL
authors: Mills
mesh_terms: D000293:Adolescent; D000328:Adult; D000428:Alcohol Drinking / Q000009:adverse effects* / Q000453:epidemiology / Q000401:mortality; D036861:Delivery, Obstetric / Q000706:statistics & numerical data; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy; D011248:Pregnancy Complications / Q000453:epidemiology / Q000401:mortality; D047928:Premature Birth / Q000139:chemically induced / Q000453:epidemiology*; D011297:Prenatal Exposure Delayed Effects / Q000139:chemically induced / Q000453:epidemiology* / Q000401:mortality*; D012307:Risk Factors; D050497:Stillbirth / Q000453:epidemiology*; D055815:Young Adult