title: A previously unreported malignancy of the thyroid.
abstract: Ameloblastic fibrosarcoma or ameloblastic sarcoma is an extremely rare odontogenic neoplasm. We report a case of an ameloblastic fibrosarcoma arising from thyroid gland in a 44 year-old woman. Following total thyroidectomy, a histopathologic, immunohistologic, and genotypic examination revealed ameloblastic fibrosarcoma. The tumor was composed of odontogenic epithelium, resembling that of ameloblastoma, and a mesenchymal part exhibiting features of fibrosarcoma. To our review, our case represents the first report of ameloblastic fibrosarcoma of the thyroid gland. Ameloblastic fibrosarcoma may arise from thyroid gland.
authors: Department of Internal Medicine, Division of Medical Oncology, Gazi University Medical School, Besevler, Ankara 06500, Turkey. caretta06@hotmail.com
authors: Bulent
authors: B
authors: Cetin
authors: Suleyman
authors: S
authors: Buyukberber
authors: Senem
authors: S
authors: Senturk
authors: Omer
authors: O
authors: Uluoglu
authors: Ugur
authors: U
authors: Coskun
authors: Mustafa
authors: M
authors: Benekli
mesh_terms: D000328:Adult; D000565:Ameloblasts / Q000378:metabolism / Q000473:pathology*; D017809:Fatal Outcome; D005260:Female; D005354:Fibrosarcoma / Q000378:metabolism / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D013964:Thyroid Neoplasms / Q000378:metabolism / Q000473:pathology*