title: Reinvestigation of the synthesis of isoliquiritigenin: application of Horner-Wadsworth-Emmons reaction and Claisen-Schmidt condensation.
abstract: Isoliquiritigenin [ILG, (E)-1] was readily prepared via the Horner-Wadsworth-Emmons reactions using β-ketophosphonates 5a, b. An improved protocol for the synthesis of (E)-1 via the Claisen-Schmidt condensation was also presented.
authors: Graduate School of Pharmaceutical Sciences, The University of Tokushima, Tokushima, Japan. ssano@ph.tokushima-u.ac.jp
authors: Shigeki
authors: S
authors: Sano
authors: Yoshinori
authors: Y
authors: Okubo
authors: Atsushi
authors: A
authors: Handa
authors: Michiyasu
authors: M
authors: Nakao
authors: Syuji
authors: S
authors: Kitaike
authors: Yoshimitsu
authors: Y
authors: Nagao
authors: Hisao
authors: H
authors: Kakegawa
mesh_terms: D047188:Chalcones / Q000138:chemical synthesis* / Q000737:chemistry; D013229:Stearic Acids / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D047188:Chalcones; D013229:Stearic Acids; C028241:16-ketostearic acid; C040920:isoliquiritigenin