title: Automatic measurement of midline shift on deformed brains using multiresolution binary level set method and Hough transform.
abstract: Midline shift (MLS) is an important quantitative feature clinicians use to evaluate the severity of brain compression by various pathologies. The midline consists of many anatomical structures including the septum pellucidum (SP), a thin membrane between the frontal horns (FH) of the lateral ventricles. We proposed a procedure that can measure MLS by recognizing the SP within the given CT study. The FH region is selected from all ventricular regions by expert rules and the multiresolution binary level set method. The SP is recognized using Hough transform, weighted by repeated morphological erosion. Our system is tested on images from 80 patients admitted to the neurosurgical intensive care unit. The results are evaluated by human experts. The mean difference between automatic and manual MLS measurements is 0.23 ± 0.52 mm. Our method is robust and can be applied in emergency and routine settings.
authors: Institute of Biomedical Engineering, National Taiwan University, No. 1, Sec. 1, Jen-Ai Road, Taipei, Taiwan.
authors: Furen
authors: F
authors: Xiao
authors: I-Jen
authors: IJ
authors: Chiang
authors: Jau-Min
authors: JM
authors: Wong
authors: Yi-Hsin
authors: YH
authors: Tsai
authors: Ke-Chun
authors: KC
authors: Huang
authors: Chun-Chih
authors: CC
authors: Liao
mesh_terms: D000465:Algorithms; D001921:Brain / Q000033:anatomy & histology / Q000000981:diagnostic imaging* / Q000473:pathology*; D001929:Brain Edema / Q000000981:diagnostic imaging / Q000473:pathology; D016208:Databases, Factual; D006801:Humans; D007362:Intensive Care Units; D020300:Intracranial Hemorrhages / Q000473:pathology; D011857:Radiographic Image Interpretation, Computer-Assisted / Q000379:methods*; D012688:Septum Pellucidum / Q000033:anatomy & histology* / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed / Q000379:methods*