title: Osteolytic mandible presenting as an initial manifestation of an adult acute lymphoblastic leukaemia.
abstract: A case of adult acute lymphoblastic leukaemia is reported. A 35-year-old male presented with an osteolytic lesion of the mandible. There was no definitive involvement in other craniofacial bones. A panoramic radiograph taken 4 months previously showed no bony involvement. A complete blood count showed a slightly decreased red blood cell count, but normal white blood cell count, white blood cell differential count and platelet count. Routine chemistry revealed hypercalcemia with an increased level of parathyroid hormone-related protein. Histopathological examination of bone marrow biopsy confirmed the diagnosis of acute lymphoblastic leukaemia.
authors: Department of Oral and Maxillofacial Surgery, College of Dentistry, Yonsei University, South Korea.
authors: S-W
authors: SW
authors: Chung
authors: S
authors: S
authors: Kim
authors: J R
authors: JR
authors: Choi
authors: T-H
authors: TH
authors: Yoo
authors: I-H
authors: IH
authors: Cha
mesh_terms: D000328:Adult; D016301:Alveolar Bone Loss / Q000175:diagnosis; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D006801:Humans; D006934:Hypercalcemia / Q000175:diagnosis; D008297:Male; D008336:Mandibular Diseases / Q000175:diagnosis*; D064847:Multimodal Imaging; D010014:Osteolysis / Q000175:diagnosis*; D044162:Parathyroid Hormone-Related Protein / Q000097:blood; D049268:Positron-Emission Tomography; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000175:diagnosis*; D011862:Radiography, Panoramic; D014057:Tomography, X-Ray Computed
chemical_list: D044162:Parathyroid Hormone-Related Protein