title: Clinical Course before and after Cataract and Glaucoma Surgery under Systemic Infliximab Therapy in Patients with Behçet's Disease.
abstract: OBJECTIVE
  Patients with Behçet's disease often need intraocular surgeries for the treatment of secondary cataract or glaucoma. This study aims to report the clinical course before and after the intraocular surgeries of 5 patients who were systematically treated with infliximab.
  
  
  METHODS
  Retrospective case series.
  
  
  RESULTS
  Seven eyes of 5 male patients with Behçet's disease, who underwent intraocular surgery while under systemic infliximab therapy at Yokohama City University Hospital from 2007 to 2009, were included in the study. The mean age at surgery was 44.2 years. Phacoemulsification was performed on 4 eyes, and trabeculectomy was done on the remaining 3 eyes. The mean duration since the onset of the ocular symptoms was 107 months. Control of the ocular attacks with the use of other systemic medications was difficult for all patients; however, the use of infliximab enabled adequate control of the attacks. The visual acuity status during the preoperative stage did not worsen during the postoperative period. No infectious complication was observed in all cases.
  
  
  CONCLUSIONS
  Our results suggest that infliximab treatment does not complicate any subsequent intraocular surgery. Patients with Behçet's disease in need of intraocular surgery can benefit from control of attacks with infliximab treatment.
authors: Department of Ophthalmology, Hospital of National Rehabilitation Center for Persons with Disabilities, Tokorozawa, Japan.
authors: Tomomi
authors: T
authors: Nishida
authors: Etsuko
authors: E
authors: Shibuya
authors: Yuri
authors: Y
authors: Asukata
authors: Satoshi
authors: S
authors: Nakamura
authors: Mami
authors: M
authors: Ishihara
authors: Kiyofumi
authors: K
authors: Hayashi
authors: Mitsuhiro
authors: M
authors: Takeno
authors: Yoshiaki
authors: Y
authors: Ishigatsubo
authors: Nobuhisa
authors: N
authors: Mizuki