title: Functional ultrasound imaging of the brain.
abstract: We present functional ultrasound (fUS), a method for imaging transient changes in blood volume in the whole brain at better spatiotemporal resolution than with other functional brain imaging modalities. fUS uses plane-wave illumination at high frame rate and can measure blood volumes in smaller vessels than previous ultrasound methods. fUS identifies regions of brain activation and was used to image whisker-evoked cortical and thalamic responses and the propagation of epileptiform seizures in the rat brain.
authors: Institut Langevin, Ecole Supérieure de Physique et de Chimie Industrielles Paris Tech, Centre National de la Recherche Scientifique (CNRS) UMR7587, Institut National de la Santé et de la Recherche Médicale U979, Université Paris VII, Paris, France.
authors: Emilie
authors: E
authors: Macé
authors: Gabriel
authors: G
authors: Montaldo
authors: Ivan
authors: I
authors: Cohen
authors: Michel
authors: M
authors: Baulac
authors: Mathias
authors: M
authors: Fink
authors: Mickael
authors: M
authors: Tanter
mesh_terms: D000465:Algorithms; D000818:Animals; D001921:Brain / Q000503:physiopathology*; D001931:Brain Mapping / Q000379:methods*; D005071:Evoked Potentials; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D051381:Rats; D014463:Ultrasonography / Q000379:methods*