title: Extracorporeal membrane oxygenation as rescue therapy for methadone-induced pulmonary edema.
abstract: Opioid-induced pulmonary edema has been previously reported, but its mechanism remains unclear. The use of extracorporeal membrane oxygenation as rescue therapy for methadone-induced pulmonary edema has not been reported in the literature. We describe 2 cases of methadone ingestion complicated by pulmonary edema, acute respiratory distress syndrome, and circulatory failure successfully managed with venoarterial extracorporeal membrane oxygenation.
authors: Golisano Children's Hospital at Strong, University of Rochester Medical Center, Rochester, NY 14642, USA. louis_daugherty@urmc.rochester.edu
authors: Louis Eugene
authors: LE
authors: Daugherty
mesh_terms: D000293:Adolescent; D004632:Emergency Medical Services; D015199:Extracorporeal Membrane Oxygenation; D005260:Female; D006333:Heart Failure / Q000139:chemically induced / Q000628:therapy; D006801:Humans; D008297:Male; D008691:Methadone / Q000009:adverse effects*; D009294:Narcotics / Q000009:adverse effects*; D011654:Pulmonary Edema / Q000139:chemically induced* / Q000503:physiopathology / Q000628:therapy*; D012128:Respiratory Distress Syndrome / Q000139:chemically induced / Q000628:therapy; D055815:Young Adult
chemical_list: D009294:Narcotics; D008691:Methadone