title: Isointricatinol, a new antioxidant homoisoflavonoid from the roots of Caesalpinia digyna Rottler.
abstract: A new homoisoflavonoid, isointricatinol (1), together with eight known homoisoflavonoids, three flavonoids, bergenin and 11-O-galloylbergenin were isolated from the EtOAc fraction of MeOH extract of Caesalpinia digyna roots and evaluated for the antioxidant activity against DPPH and ABTS free radicals. The structure of 1 was elucidated by various spectroscopic techniques and found to be a Z-isomer of 7,8-dihydroxy-3-(4'-methoxybenzyl)chroman-4-one. Compound 1 was found to exhibit mild to moderate free radical scavenging effect against DPPH (IC(50), 85.50 µM) and ABTS (IC(50), 44.13 µM) radicals.
authors: Department of Natural Products, National Institute of Pharmaceutical Education and Research (NIPER), Sector-67, SAS Nagar, Mohali-160062, Punjab, India.
authors: S K
authors: SK
authors: Roy
authors: U C
authors: UC
authors: Agrahari
authors: R
authors: R
authors: Gautam
authors: A
authors: A
authors: Srivastava
authors: S M
authors: SM
authors: Jachak
mesh_terms: D052160:Benzothiazoles; D001713:Biphenyl Compounds; D029911:Caesalpinia / Q000737:chemistry*; D016166:Free Radical Scavengers / Q000032:analysis*; D007529:Isoflavones / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D010851:Picrates; D018517:Plant Roots / Q000737:chemistry; D013451:Sulfonic Acids
chemical_list: D052160:Benzothiazoles; D001713:Biphenyl Compounds; D016166:Free Radical Scavengers; D007529:Isoflavones; D010851:Picrates; D013451:Sulfonic Acids; C574482:isointricatinol; C002502:2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid; C004931:1,1-diphenyl-2-picrylhydrazyl