title: The submucosal cushion does not improve the histologic evaluation of adenomatous colon polyps resected by snare polypectomy.
abstract: OBJECTIVE
  Although the "submucosal cushion" technique or injection-assisted polypectomy (IAP) is often used to resect colon polyps, little is known on the influence of this technique on histologic interpretation. We aimed to evaluate whether the use of a submucosal cushion improves the histologic and margin evaluation of colon polyps.
  
  
  METHODS
  Consecutive patients undergoing polypectomy with and without IAP were included. An experienced blinded gastrointestinal pathologist evaluated the specimens using standardized criteria.
  
  
  RESULTS
  One hundred eleven sessile colon adenomas were analyzed (IAP, n = 65, standard, n = 46). Two-thirds of polyps ranged in size from 10 to 20 mm; the average polyp size was 13.2 mm for IAP and 9.9 mm for standard snare polypectomy (P = .001). The cautery degree, cautery amount, and margin evaluability, did not differ substantially with regard to the resection technique. For polyps ≥10-20 mm, the overall architecture quality was better in polyps resected with standard technique as compared with IAP.
  
  
  CONCLUSIONS
  The utilization of IAP did not result in a better margin evaluability of the resected polyp. Overall, IAP does not result in a better histologic polyp evaluability.
authors: Clinic for Gastroenterology and Hepatology, Clinical Center of Serbia, Belgrade, Serbia.
authors: Ivan
authors: I
authors: Jovanovic
authors: Carlos
authors: C
authors: Caro
authors: Helmut
authors: H
authors: Neumann
authors: Anke
authors: A
authors: Lux
authors: Doerthe
authors: D
authors: Kuester
authors: Lucia C
authors: LC
authors: Fry
authors: Peter
authors: P
authors: Malfertheiner
authors: Klaus
authors: K
authors: Mönkemüller
mesh_terms: D000368:Aged; D003110:Colonic Neoplasms / Q000175:diagnosis* / Q000473:pathology* / Q000601:surgery; D005260:Female; D006651:Histocytochemistry / Q000379:methods; D006801:Humans; D007413:Intestinal Mucosa / Q000473:pathology* / Q000601:surgery; D008297:Male; D008853:Microscopy / Q000379:methods; D008875:Middle Aged; D011127:Polyps / Q000175:diagnosis* / Q000473:pathology* / Q000601:surgery; D013514:Surgical Procedures, Operative / Q000379:methods*