title: Prognostic indicators for no light perception after open-globe injury: eye injury vitrectomy study.
abstract: OBJECTIVE
  To describe ocular characteristics, surgical interventions, and anatomic and visual outcomes of traumatized eyes with no light perception (NLP) following open-globe injury and to investigate prognostic predictors for NLP cases after open-globe injury.
  
  
  METHODS
  Interventional case series study.
  
  
  METHODS
  Thirty-three traumatized eyes with NLP were selected from the Eye Injury Vitrectomy Study database, a hospital-based multicenter prospective cohort study. Inclusion criteria were NLP cases following open-globe injury with outcomes of anatomic restoration, phthisis bulbi, or enucleation. Exclusion criteria were cases with missing records, undergoing vitrectomy after injury at nonparticipating hospitals, direct optic head injury, endophthalmitis, and hypotonous or silicone oil-sustained eyes. All cases underwent vitreoretinal surgery or enucleation after exploratory surgery and were followed up for at least 6 months. Two outcomes were assessed: favorable outcome (anatomically restored eye globes with light perception [LP] or better vision) and unfavorable outcome (NLP, phthisis bulbi, or enucleation).
  
  
  RESULTS
  The following 7 risk factors were significant between the 2 groups: rupture (P = .021); open globe III (P = .046); scleral wound ≥10 mm (P = .001); ciliary body damage (P < .001); severe intraocular hemorrhage (P = .005); closed funnel retinal detachment or retinal prolapse (P = .005); and choroidal damage (P = .001).
  
  
  CONCLUSIONS
  These 7 risk factors are possible predictors of poor prognosis. Traumatized eyes with NLP can be anatomically restored with LP or better vision if vitreoretinal surgery is attempted, and a favorable anatomic and visual outcome is increased by having a decreased number of these risk factors.
authors: Peking University Eye Center, Peking University Third Hospital, Beijing, People's Republic of China.
authors: Kang
authors: K
authors: Feng
authors: Yun Tao
authors: YT
authors: Hu
authors: Zhizhong
authors: Z
authors: Ma
mesh_terms: D000328:Adult; D001766:Blindness / Q000175:diagnosis* / Q000601:surgery; D002648:Child; D002829:Choroid / Q000293:injuries; D002832:Choroid Hemorrhage / Q000175:diagnosis; D002924:Ciliary Body / Q000293:injuries; D015353:Eye Enucleation; D015807:Eye Injuries, Penetrating / Q000175:diagnosis* / Q000601:surgery; D006801:Humans; D008875:Middle Aged; D011379:Prognosis; D011391:Prolapse; D011446:Prospective Studies; D012160:Retina / Q000293:injuries; D012307:Risk Factors; D012590:Sclera / Q000293:injuries; D014792:Visual Acuity / Q000502:physiology; D014821:Vitrectomy; D055815:Young Adult