title: Prevalence of low birthweight infants in HIV-infected women delivered in Rajavithi Hospital.
abstract: OBJECTIVE
  To determine the prevalence of low birthweight infants in HIV-infected pregnant women delivered in Rajavithi Hospital and the relationship between antiretroviral drugs and low birthweight infants.
  
  
  METHODS
  All numbers of low birthweight (LBW) infants and pregnant women with or without HIV infection delivered in Rajavithi Hospital during 2004-2008 from medical records were used. Two hundred HIV-infected pregnant women who delivered their infants at the same period were random for description and analysis.
  
  
  RESULTS
  The prevalence of low birthweight infants delivered by HIV and non HIV-infected pregnant women were 12.6% (53/ 420) and 13.3% (4,249/31,975), respectively. There was no significant association between HIV infection and low birthweight (p = 0.688). Low birthweight infants delivered from HIV-infected pregnant women with and without antiretroviral therapy were 9.9% (7/41) and 13.6% (19/159), respectively. Various types of antiretroviral (ARV) drug including no ARV were significantly associated with LBW (p = 0.021). The one who received highly active antiretroviral therapy (HAART) had 2.27 times higher risk in having LBW.
  
  
  CONCLUSIONS
  The prevalence of low birthweight infants among HIV-infected pregnant women was 12.6%. There was no association between HIV infection and LBW. HAART might be a risk of LBW.
authors: Department of Obstetrics and Gynecology, Rajavithi Hospital, College of Medicine, Rangsit University, Bangkok, Thailand. asuvanna@yahoo.com
authors: Suvanna
authors: S
authors: Asavapiriyanont
authors: Sineeporn
authors: S
authors: Kasiwat
mesh_terms: D000293:Adolescent; D000328:Adult; D044966:Anti-Retroviral Agents / Q000627:therapeutic use*; D023241:Antiretroviral Therapy, Highly Active; D005260:Female; D015658:HIV Infections / Q000150:complications / Q000188:drug therapy* / Q000453:epidemiology; D006784:Hospitals, Teaching; D006801:Humans; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D018445:Infectious Disease Transmission, Vertical / Q000517:prevention & control / Q000706:statistics & numerical data; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000188:drug therapy* / Q000453:epidemiology; D011256:Pregnancy Outcome / Q000453:epidemiology; D015995:Prevalence; D012189:Retrospective Studies; D012307:Risk Factors; D013785:Thailand / Q000453:epidemiology; D016896:Treatment Outcome; D019562:Viral Load; D055815:Young Adult
chemical_list: D044966:Anti-Retroviral Agents