title: Comparison of gender-specific mortality in patients < 70 years versus ≥ 70 years old with acute myocardial infarction.
abstract: The aim of the present study was to investigate the gender-specific mortality after acute myocardial infarction in those aged < 70 years versus ≥ 70 years. The present study consisted of 2,677 consecutive patients with acute myocardial infarction who had undergone coronary angiography within 24 hours after the onset of symptoms. The patients were divided into 2 groups: 1,810 patients < 70 years old and 867 patients ≥ 70 years old. Women were older and had a greater incidence of hypertension and diabetes mellitus and a lower incidence of current smoking and previous myocardial infarction in both groups. The in-hospital mortality rate was significantly greater in women ≥ 70 years old age than in men ≥ 70 years old (16.2% vs 9.3%, respectively; p = 0.003) but was comparable between women and men in patients < 70 years old (5.7% vs 4.9%, respectively; p = 0.59). On multivariate analysis, the association between female gender and in-hospital mortality in patients ≥ 70 years old remained significant (odds ratio 1.78, 95% confidential interval 1.05 to 3.00), but the gender difference was not observed in patients < 70 years old (odds ratio 1.09, 95% confidence interval 0.53 to 2.24). In conclusion, female gender was associated with in-hospital mortality after acute myocardial infarction in patients ≥ 70 years old but not in patients < 70 years old.
authors: Department of Cardiology, Hiroshima City Hospital, Hiroshima, Japan.
authors: Masaharu
authors: M
authors: Ishihara
authors: Ichiro
authors: I
authors: Inoue
authors: Takuji
authors: T
authors: Kawagoe
authors: Yuji
authors: Y
authors: Shimatani
authors: Fumiharu
authors: F
authors: Miura
authors: Yasuharu
authors: Y
authors: Nakama
authors: Kazuoki
authors: K
authors: Dai
authors: Takayuki
authors: T
authors: Ootani
authors: Kuniomi
authors: K
authors: Ooi
authors: Hiroki
authors: H
authors: Ikenaga
authors: Takashi
authors: T
authors: Miki
authors: Masayuki
authors: M
authors: Nakamura
authors: Shinji
authors: S
authors: Kishimoto
authors: Youji
authors: Y
authors: Sumimoto
mesh_terms: D000367:Age Factors; D000368:Aged; D017023:Coronary Angiography; D003920:Diabetes Mellitus / Q000453:epidemiology; D005260:Female; D017052:Hospital Mortality; D006801:Humans; D006973:Hypertension / Q000453:epidemiology; D015994:Incidence; D008297:Male; D009203:Myocardial Infarction / Q000000981:diagnostic imaging / Q000401:mortality* / Q000628:therapy; D012307:Risk Factors; D017678:Sex Distribution; D012737:Sex Factors; D012907:Smoking / Q000453:epidemiology