title: [Radioembolization with (90)Y-labeled microspheres: post-therapeutic therapy validation with Bremsstrahlung-SPECT].
abstract: During the last years angiographic Selective Internal Radiotherapy (SIRT) with (90)Y-labelled microspheres has become a common technique for the local-ablative treatment of cancer patients. SIRT is a palliative therapy concept for the treatment of liver malignancies. As a result of (90)Y-decay as β(-)-emitter without a concomitant gamma radiation, Bremsstrahlung imaging is needed to validate the distribution achieved by radioembolisation. This article demonstrates the method of imaging through phantom measurement and shows the advantages of post-therapeutic tomography by means of a patient study. Approaches for further optimization of Bremsstrahlung imaging are discussed.
authors: Klinik für Radiologie und Nuklearmedizin, Universitätsklinikum Magdeburg A.ö.R, Otto-von-Guericke-Universität, Deutschland.
authors: Oliver S
authors: OS
authors: Grober
authors: Madeleine
authors: M
authors: Nultsch
authors: Kathleen
authors: K
authors: Laatz
authors: Gerd
authors: G
authors: Ulrich
authors: Ricarda
authors: R
authors: Seidensticker
authors: Annette
authors: A
authors: Pethe
authors: Oliver
authors: O
authors: Dudeck
authors: Maciej
authors: M
authors: Pech
authors: Bernd O
authors: BO
authors: Knoop
authors: Jens
authors: J
authors: Ricke
authors: Holger
authors: H
authors: Amthauer
authors: Lilli
authors: L
authors: Geworski
mesh_terms: D001822:Body Burden; D004307:Dose-Response Relationship, Radiation; D004621:Embolization, Therapeutic / Q000379:methods*; D006801:Humans; D008099:Liver / Q000098:blood supply; D008113:Liver Neoplasms / Q000532:radiotherapy*; D008863:Microspheres; D010166:Palliative Care; D019047:Phantoms, Imaging; D011880:Radiotherapy Planning, Computer-Assisted / Q000379:methods*; D015899:Tomography, Emission-Computed, Single-Photon / Q000379:methods*; D016896:Treatment Outcome; D015021:Yttrium Radioisotopes / Q000493:pharmacokinetics / Q000627:therapeutic use*
chemical_list: D015021:Yttrium Radioisotopes