title: Seroprevalence to cytomegalovirus in the Portuguese population, 2002-2003.
abstract: The prevalence of cytomegalovirus (CMV) infections ranges between 50% and 85% in adults in the United States, and its epidemiology varies in different regions of the world and between socioeconomic and age groups. In Portugal, no study has been carried out to date to determine the prevalence of CMV in the general population. Under the second National Serological Survey conducted in continental Portugal in 2001–2002, we estimated the prevalence of individuals with antibodies to CMV using indirect immunofluorescence to detect virus-specific IgG. The population sample included 2,143 individuals of both sexes and different ages from all 18 districts in Portugal. The national seroprevalence of CMV was determined as 77%. We analysed the proportion of CMV IgG by sex, age group and district of residence. This was the first nationally representative study of seroprevalence of CMV in Portugal. The results of the study indicate that CMV infection is highly prevalent in the population and occurs mainly in the first years of life.
authors: Department of Infectious Diseases, National Institute of Health, Lisbon, Portugal. silvia.lopo@insa.min-saude.pt
authors: S
authors: S
authors: Lopo
authors: E
authors: E
authors: Vinagre
authors: P
authors: P
authors: Palminha
authors: M T
authors: MT
authors: Paixao
authors: P
authors: P
authors: Nogueira
authors: M G
authors: MG
authors: Freitas
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D000914:Antibodies, Viral / Q000097:blood*; D002648:Child; D002675:Child, Preschool; D003587:Cytomegalovirus / Q000276:immunology*; D003586:Cytomegalovirus Infections / Q000097:blood / Q000453:epidemiology* / Q000276:immunology; D005260:Female; D019084:Fluorescent Antibody Technique, Indirect; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D008297:Male; D008875:Middle Aged; D011159:Population Surveillance; D011174:Portugal / Q000453:epidemiology; D012307:Risk Factors; D016036:Seroepidemiologic Studies; D012698:Serologic Tests; D017678:Sex Distribution
chemical_list: D000914:Antibodies, Viral; D007074:Immunoglobulin G