title: Association study of DRD3 gene in schizophrenia in Mexican sib-pairs.
abstract: Schizophrenia is a heritable, complex mental disorder. We analysed the DRD3 gene as a candidate to be related to schizophrenia and clinical features in affected sib-pairs. A positive association with the -250A/Ser9 haplotype and a trend toward an association with formal thought disorder were observed. A synergic effect of DRD3 polymorphisms on schizophrenia susceptibility is suggested.
authors: Genetics Laboratory, Instituto Nacional de Psiquiatría Ramón de la Fuente, Mexico City, Mexico. urracanora@yahoo.com
authors: Nora
authors: N
authors: Urraca
authors: Beatriz
authors: B
authors: Camarena
authors: Alejandro
authors: A
authors: Aguilar
authors: Ana
authors: A
authors: Fresán
authors: Rogelio
authors: R
authors: Apiquián
authors: Lorena
authors: L
authors: Orozco
authors: Alessandra
authors: A
authors: Carnevale
authors: Humberto
authors: H
authors: Nicolini
mesh_terms: D000328:Adult; D005260:Female; D056726:Genetic Association Studies; D020022:Genetic Predisposition to Disease; D005838:Genotype; D005998:Glycine / Q000235:genetics; D006801:Humans; D008297:Male; D008800:Mexico; D020641:Polymorphism, Single Nucleotide / Q000235:genetics*; D050637:Receptors, Dopamine D3 / Q000235:genetics*; D012559:Schizophrenia / Q000235:genetics*; D012694:Serine / Q000235:genetics; D035781:Siblings; D055815:Young Adult
chemical_list: D050637:Receptors, Dopamine D3; D012694:Serine; D005998:Glycine