title: Birth outcomes of intended pregnancies among women who used assisted reproductive technology, ovulation stimulation, or no treatment.
abstract: OBJECTIVE
  To study birth outcomes among live born infants conceived by women who used infertility treatment.
  
  
  METHODS
  Population-based surveillance of women who recently delivered a live infant.
  
  
  METHODS
  The birth outcomes among infants whose mothers used assisted reproductive technology (ART) or ovulation stimulation medications alone were compared with the outcomes of infants conceived without treatment.
  
  
  METHODS
  Stratified random sample of women who were attempting conception and gave birth to a live infant in six US states (n = 16,748).
  
  
  METHODS
  Assisted reproductive technology and ovulation stimulation.
  
  
  METHODS
  Adjusted odds ratios for perinatal outcomes.
  
  
  RESULTS
  The prevalence of infertility treatment use overall among women attempting conception was 10.9% (5.4% ART procedures, 5.5% ovulation stimulation medications). Singletons of mothers who received ART procedures were more likely to be born with low birthweight, preterm, and small for gestational age (SGA) than singleton infants conceived without treatment. Singleton infants of mothers who used ovulation stimulation medications alone were more likely to be SGA than singleton infants conceived without treatment. No differences were found between ART and no treatment twin infants.
  
  
  CONCLUSIONS
  Among singleton infants, ART is associated with decreased fetal growth, decreased gestational length, and SGA; ovulation stimulation alone is associated with SGA.
authors: Division of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, 4770 Buford Highway, NE Mailstop K-22, Atlanta, Georgia 30341, USA. DDAngelo@cdc.gov
authors: Denise V
authors: DV
authors: D'Angelo
authors: Nedra
authors: N
authors: Whitehead
authors: Kristen
authors: K
authors: Helms
authors: Wanda
authors: W
authors: Barfield
authors: Indu B
authors: IB
authors: Ahluwalia
mesh_terms: D000328:Adult; D005260:Female; D005317:Fetal Growth Retardation / Q000209:etiology; D005865:Gestational Age; D006801:Humans; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D007234:Infant, Premature; D007246:Infertility / Q000628:therapy*; D050498:Live Birth; D016017:Odds Ratio; D010062:Ovulation Induction / Q000009:adverse effects; D011247:Pregnancy; D011256:Pregnancy Outcome; D018873:Pregnancy Rate; D027724:Reproductive Techniques, Assisted / Q000009:adverse effects; D018570:Risk Assessment; D012307:Risk Factors; D016896:Treatment Outcome; D014481:United States; D055815:Young Adult