title: The use of reverse thermosensitive polymer (LeGoo) for temporary vessel occlusion in clampless peripheral vascular surgery.
abstract: BACKGROUND
  There is a need to develop methods of vascular hemostasis, which limit vessel trauma. LeGoo is a reverse thermosensitive polymer (poloxamer) which is a viscous liquid at room temperature, becoming a firm plug at body temperature. We aimed to describe early single center experience in clampless peripheral vascular surgery.
  
  
  METHODS
  Single surgeon experience using LeGoo during peripheral vascular surgery between February and October 2010 was analyzed.
  
  
  RESULTS
  LeGoo was used in 13 anastomoses in 11 patients. A satisfactory bloodless field without the use of conventional occlusion devices was achieved in 92% of anastomoses. At a median of 36 weeks follow-up, total conduit patency was 91%.
  
  
  CONCLUSIONS
  In this small series, LeGoo was seen to be safe and effective in the provision of a clamp-free bloodless field in the context of peripheral vascular surgery. Prospective comparative study is necessary to determine performance against conventional vascular clamps.
authors: Department of Vascular Surgery, Imperial Vascular Unit, Charing Cross Hospital, Imperial College London, London, UK. j.shalhoub@imperial.ac.uk
authors: Joseph
authors: J
authors: Shalhoub
authors: Ankur
authors: A
authors: Thapar
authors: Alun H
authors: AH
authors: Davies
mesh_terms: D000328:Adult; D000368:Aged; D001166:Arteriovenous Shunt, Surgical / Q000009:adverse effects; D016063:Blood Loss, Surgical / Q000517:prevention & control*; D005260:Female; D006488:Hemostasis, Surgical / Q000379:methods*; D006801:Humans; D008131:London; D008297:Male; D008875:Middle Aged; D020442:Poloxamer / Q000737:chemistry / Q000627:therapeutic use*; D013696:Temperature; D013997:Time Factors; D016896:Treatment Outcome; D018616:Ultrasonography, Doppler, Duplex; D058017:Vascular Grafting / Q000009:adverse effects; D014654:Vascular Patency; D014680:Veins / Q000637:transplantation*
chemical_list: C539704:LeGoo; D020442:Poloxamer