title: Systemic therapy of psoriasis: methotrexate.
abstract: Methotrexate is the first line therapy for the treatment of moderate to severe psoriasis and psoriatic arthritis all over the world. It has immunosupressive and anti-inflammatory effects. If we want to use it, we have to know its mechanism of action and also its possible toxicity and how to cope with it (Tab. 3, Fig. 1, Ref. 14).
authors: Department of Dermatology, Faculty of Medicine, University Hospital, Bratislava, Slovakia. peter.kozub@laposte.net
authors: P
authors: P
authors: Kozub
authors: M
authors: M
authors: Simaljakova
mesh_terms: D000893:Anti-Inflammatory Agents / Q000008:administration & dosage* / Q000009:adverse effects; D015535:Arthritis, Psoriatic / Q000188:drug therapy*; D005493:Folic Acid Antagonists / Q000008:administration & dosage* / Q000009:adverse effects; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage* / Q000009:adverse effects; D008727:Methotrexate / Q000008:administration & dosage* / Q000009:adverse effects; D011565:Psoriasis / Q000188:drug therapy*
chemical_list: D000893:Anti-Inflammatory Agents; D005493:Folic Acid Antagonists; D007166:Immunosuppressive Agents; D008727:Methotrexate