title: Immunopathology of allergic contact dermatitis.
abstract: Allergic contact dermatitis is the consequence of an immune reaction mediated by T cells against low molecular weight chemicals known as haptens. It is a common condition that occurs in all races and age groups and affects the quality of life of those who present it. The immunological mechanism of this disease has been reviewed in recent decades with significant advance in its understanding. The metabolism and pathway of the haptens as well as the activation and mechanism of action of the cells responsible for both the immune reaction and its completion are discussed in this article.
authors: Universidade Federal do Paraná, Curitiba, PR, Brasil. hd330@yahoo.com
authors: Luis Eduardo Agner Machado
authors: LE
authors: Martins
authors: Vitor Manoel Silva Dos
authors: VM
authors: Reis
mesh_terms: D016207:Cytokines / Q000276:immunology; D017449:Dermatitis, Allergic Contact / Q000276:immunology*; D006241:Haptens / Q000276:immunology; D006801:Humans; D007801:Langerhans Cells / Q000276:immunology; D050378:T-Lymphocytes, Regulatory / Q000276:immunology
chemical_list: D016207:Cytokines; D006241:Haptens