title: Lianqiaoxinoside B, a novel caffeoyl phenylethanoid glycoside from Forsythia suspensa.
abstract: Chemical investigation of the 70% ethanol extract of the unripe fruits of Forsythia suspensa resulted in the isolation of a novel caffeoyl phenylethanoid glycoside, lianqiaoxinoside B, together with the known compound forsythoside H. The new compound was elucidated to be 1'',2''-[β-(3,4,-dihydroxylphenyl)-α,β-dioxoethanol]-3''-O-caffeoyl-O-α-rhamnopyranosyl-(1→6)-O-β-glucopyranoside by extensive spectroscopic and chemical studies. Lianqiaoxinoside B and forsythoside H showed strong antioxidant and antimicrobial activities in vitro by the 2,2'-azinobis-3-ethylbenzothiazoline-6-sulphonate (ABTS) radical-scavenging assay and plate method. This study can be further extended to exploit for the possible application of caffeoyl phenylethanoid glycosides as the alternative antioxidants and antimicrobial agents of natural origin.
authors: Key Laboratory of Chinese Materia Medica, Heilongjiang University of Chinese Medicine, Ministry of Education, Harbin 150040, China. hxkuang@hotmail.com
authors: Hai-Xue
authors: HX
authors: Kuang
authors: Yong-Gang
authors: YG
authors: Xia
authors: Jun
authors: J
authors: Liang
authors: Bing-You
authors: BY
authors: Yang
authors: Qiu-Hong
authors: QH
authors: Wang
mesh_terms: D000975:Antioxidants / Q000737:chemistry; D031657:Forsythia / Q000737:chemistry*; D006027:Glycosides / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure
chemical_list: D000975:Antioxidants; D006027:Glycosides