title: The effect of permanent grafting materials on the preservation of the buccal bone plate after tooth extraction: an experimental study in the dog.
abstract: OBJECTIVE
  The aim of the present study was to evaluate the effects of a novel bone substitute system (Natix(®)), consisting of porous titanium granules (PTG) and a bovine-derived xenograft (Bio-Oss(®)), on hard tissue remodelling following their placement into fresh extraction sockets in dogs.
  
  
  METHODS
  Six modalities were tested; Natix(®) granules with and without a covering double-layered Bio Gide(®) membrane; Bio-Oss(®) with and without a covering double-layered Bio Gide(®) membrane; and a socket left empty with and without a covering double-layered Bio Gide(®) membrane. Linear measurements, indicative of buccal bone height loss, and an area measurement indicative of buccal bulk bone loss were made. The statistical analysis was based on the Latin Square design with two blocking factors (dog and site). Tukey's post hoc test was used to adjust for multiple comparisons.
  
  
  RESULTS
  Histological observation revealed that while bone formed around both the xenograft and the titanium particles, bone was also noted within titanium granules. Of the five modalities of ridge preservation techniques used in this study, no one technique proved to be superior.
  
  
  CONCLUSIONS
  The titanium granules were observed to have promising osseoconductive properties.
authors: Dublin Dental School and Hospital, Division of Restorative Dentistry and Periodontology, Dublin, Ireland.
authors: Haitham
authors: H
authors: Bashara
authors: Johan Caspar
authors: JC
authors: Wohlfahrt
authors: Ioannis
authors: I
authors: Polyzois
authors: Staale Petter
authors: SP
authors: Lyngstadaas
authors: Stefan
authors: S
authors: Renvert
authors: Noel
authors: N
authors: Claffey
mesh_terms: D016301:Alveolar Bone Loss / Q000517:prevention & control*; D000539:Alveolar Process / Q000000981:diagnostic imaging / Q000187:drug effects* / Q000473:pathology / Q000601:surgery*; D000818:Animals; D016723:Bone Remodeling / Q000187:drug effects; D018786:Bone Substitutes / Q000494:pharmacology*; D003094:Collagen / Q000494:pharmacology*; D004285:Dogs; D008903:Minerals / Q000494:pharmacology*; D012984:Software; D013524:Surgical Flaps; D014025:Titanium / Q000494:pharmacology*; D014057:Tomography, X-Ray Computed; D014081:Tooth Extraction; D020390:Tooth Socket / Q000000981:diagnostic imaging / Q000601:surgery*; D014183:Transplantation, Heterologous
chemical_list: C106416:Bio-Gide; C077540:Bio-Oss; D018786:Bone Substitutes; D008903:Minerals; C577189:Natix; D003094:Collagen; D014025:Titanium