title: Aminothiophenedicarboxamides and dicyanothiopheneacetamides as effective synthetic molluscicides against Indoplanorbis exustus snail.
abstract: New thiophenedicarboxamide 2a-c and dicyanothiopheneacetamide 3a-c derivatives were synthesized and their bioactivity against Indoplanorbis exustus snails was evaluated. The I. exustus snail is a serious host of parasite of genus Schistosoma which infects cattle. Thus reduces livestock productivity and also acts as a source of cercarial dermatitis in human beings. The results obtained show a significant (P < 0.05) molluscicidal activity with LC(50) = 0.6043 ppm for compound 2a and LC(50) = 0.6511 ppm for compound 3a.
authors: Organic Chemistry Research Center, Department of Chemistry, KTHM College, Gangapur Road, Nashik 422 002, MS, India.
authors: Shrikant B
authors: SB
authors: Kanawade
authors: Raghunath B
authors: RB
authors: Toche
authors: Shivaraj P
authors: SP
authors: Patil
authors: Ashok E
authors: AE
authors: Desai
authors: Sapana S
authors: SS
authors: Bhamare
mesh_terms: D000818:Animals; D020128:Inhibitory Concentration 50; D009682:Magnetic Resonance Spectroscopy; D012908:Snails / Q000187:drug effects*; D013055:Spectrophotometry, Infrared; D013876:Thiophenes / Q000494:pharmacology*
chemical_list: D013876:Thiophenes