title: Encephalocraniocutaneous lipomatosis: a rare case with development of diffuse leptomeningeal lipomatosis during childhood.
abstract: We describe the uncommon development of leptomeningeal lipomatosis in a girl with encephalocraniocutaneous lipomatosis (ECCL). Leptomeningeal involvement had not been present at 2 years of age, but was demonstrated on CT and MRI at 10 years of age. Our case demonstrates follow-up neuroimaging features of ECCL that may be helpful to radiologists in suggesting the correct diagnosis, as ocular and cutaneous lesions may be non-specific clinically. The developmental nature of leptomeningeal involvement in our case suggests that close clinical and radiological follow-up is important in children with suspected or established ECCL.
authors: Department of Diagnostic Radiology and Organ Imaging, The Chinese University of Hong Kong, Prince of Wales Hospital, Ngan Shing Street, Shatin, New Territories, Hong Kong, China. leekalok2909@yahoo.com.hk
authors: Ryan K L
authors: RK
authors: Lee
authors: Phoenix P Y
authors: PP
authors: Lui
authors: Cina S L
authors: CS
authors: Tong
authors: Winnie C W
authors: WC
authors: Chu
mesh_terms: D000293:Adolescent; D001927:Brain Diseases / Q000175:diagnosis*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008068:Lipomatosis / Q000175:diagnosis*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D014057:Tomography, X-Ray Computed / Q000379:methods*