title: Clinicopathological characteristics of mucinous and non-mucinous adenocarcinoma in the colon and rectum in Rajavithi Hospital, Thailand.
abstract: BACKGROUND
  The clinicopathological characteristics of colorectal mucinous adenocarcinoma (MA) are still controversial. Most of the reports suggested that MA were associated with worse clinicopathological behavior and poorer prognosis than non-mucinous adenocarcinoma (NMA) while the others showed no difference.
  
  
  OBJECTIVE
  To compare clinicopathological characteristics and tumor recurrence of MA patients with those in NMA patients.
  
  
  METHODS
  During the period of 2000 to 2009 in Rajavithi Hospital, a total of 427 colorectal adenocarcinoma patient records consisting of 407 NMA and 20 MA were included in this study. Mean age, tumor location, TNM staging at diagnosis, T-stage, N-stage, preoperative CEA level and recurrent rate of MA patients were compared with those of NMA patients.
  
  
  RESULTS
  The distribution of MA patients for gender, mean age, tumor location, TNM stage and preoperative CEA level were similar to those of NMA patients (all p > 0.05). Only the tumor recurrence in MA was significantly more common than that in NMA (p = 0.020, OR = 3.28 (1.14-9.43)), whereas the TNM stage was not significantly different from NMA (p = 0.530). The metastatic site and pattern of metastasis also showed no statistical significance (p = 0.125).
  
  
  CONCLUSIONS
  The prognosis of MA is poorer than NMA. This may be associated with mucinous histological type itself.
authors: Department of Surgery, Rajavithi Hospital, College of Medicine, Rangsit University, Bangkok, Thailand. paiboon_jiva@yahoo.co.th
authors: Paiboon
authors: P
authors: Jivapaisarnpong
authors: Kanya
authors: K
authors: Boonthongtho
mesh_terms: D000230:Adenocarcinoma / Q000145:classification / Q000473:pathology* / Q000601:surgery; D002288:Adenocarcinoma, Mucinous / Q000145:classification / Q000453:epidemiology / Q000473:pathology* / Q000601:surgery; D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D003110:Colonic Neoplasms / Q000145:classification / Q000473:pathology* / Q000601:surgery; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011379:Prognosis; D012004:Rectal Neoplasms / Q000145:classification / Q000473:pathology* / Q000601:surgery; D017678:Sex Distribution; D013785:Thailand; D016896:Treatment Outcome; D055815:Young Adult