title: Almotriptan for menstrually related migraine.
abstract: BACKGROUND
  Approximately 50% of migrainous women associate their headache temporally to menses. Menstrually related migraine (MRM) is a disabling form of migraine characterized by attacks that are generally longer, more severe and less drug-responsive than nonmenstrual ones. Since MRM may be difficult to treat, it is important to find an appropriate treatment option for women suffering from this condition.
  
  
  METHODS
  This paper provides an overview of the clinical features of MRM, with special attention on the use of almotriptan for its treatment. Four studies on almotriptan in the treatment of MRM are present in the medical literature. Two report post hoc analyses of data derived from larger studies on the use of almotriptan for migraine treatment. One reports the results from a study specifically dedicated to MRM and one illustrates a subanalysis on the accompanying symptomatology.
  
  
  CONCLUSIONS
  Evidence demonstrates that almotriptan is a molecule with a high efficacy in the treatment of MRM and with an excellent tolerability profile when compared with other triptans. Moreover, it shows a proven ability to control migraine-associated symptoms. All these qualities play a decidedly positive role in making almotriptan a product of choice for the treatment of MRM.
authors: Besta Neurological Institute, Via Celoria 11, Milan, Italy.
authors: Gennaro
authors: G
authors: Bussone
authors: Gianni
authors: G
authors: Allais
authors: Ilaria
authors: I
authors: Castagnoli Gabellari
authors: Chiara
authors: C
authors: Benedetto
mesh_terms: D000328:Adult; D018712:Analgesics, Non-Narcotic / Q000009:adverse effects / Q000493:pharmacokinetics / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008598:Menstruation / Q000378:metabolism; D020326:Migraine without Aura / Q000188:drug therapy* / Q000209:etiology* / Q000378:metabolism / Q000503:physiopathology; D058825:Serotonin 5-HT1 Receptor Agonists / Q000009:adverse effects / Q000493:pharmacokinetics / Q000627:therapeutic use*; D014363:Tryptamines / Q000009:adverse effects / Q000493:pharmacokinetics / Q000627:therapeutic use*
chemical_list: D018712:Analgesics, Non-Narcotic; D058825:Serotonin 5-HT1 Receptor Agonists; D014363:Tryptamines; C409045:almotriptan