title: Moorea producens gen. nov., sp. nov. and Moorea bouillonii comb. nov., tropical marine cyanobacteria rich in bioactive secondary metabolites.
abstract: The filamentous cyanobacterial genus Moorea gen. nov., described here under the provisions of the International Code of Botanical Nomenclature, is a cosmopolitan pan-tropical group abundant in the marine benthos. Members of the genus Moorea are photosynthetic (containing phycocyanin, phycoerythrin, allophycocyanin and chlorophyll a), but non-diazotrophic (lack heterocysts and nitrogenase reductase genes). The cells (discoid and 25-80 µm wide) are arranged in long filaments (<10 cm in length) and often form extensive mats or blooms in shallow water. The cells are surrounded by thick polysaccharide sheaths covered by a rich diversity of heterotrophic micro-organisms. A distinctive character of this genus is its extraordinarily rich production of bioactive secondary metabolites. This is matched by genomes rich in polyketide synthase and non-ribosomal peptide synthetase biosynthetic genes which are dedicated to secondary metabolism. The encoded natural products are sometimes responsible for harmful algae blooms and, due to morphological resemblance to the genus Lyngbya, this group has often been incorrectly cited in the literature. We here describe two species of the genus Moorea: Moorea producens sp. nov. (type species of the genus) with 3L(T) as the nomenclature type, and Moorea bouillonii comb. nov. with PNG5-198(R) as the nomenclature type.
authors: Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, and the Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, USA.
authors: Niclas
authors: N
authors: Engene
authors: National Center for Microscopy and Imaging Research, University of California San Diego, La Jolla, CA, USA.
authors: Erin C
authors: EC
authors: Rottacker
authors: Faculty of Science, University of South Bohemia, České Budějovice, Czech Republic.
authors: Jan
authors: J
authors: Kaštovský
authors: Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, and the Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, USA.
authors: Tara
authors: T
authors: Byrum
authors: Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, and the Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, USA.
authors: Hyukjae
authors: H
authors: Choi
authors: National Center for Microscopy and Imaging Research, University of California San Diego, La Jolla, CA, USA.
authors: Mark H
authors: MH
authors: Ellisman
authors: Institute of Botany, Czech Academy of Science, Dukelská 135, Třeboň, Czech Republic.|Faculty of Science, University of South Bohemia, České Budějovice, Czech Republic.
authors: Jiří
authors: J
authors: Komárek
authors: Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, and the Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, USA.
authors: William H
authors: WH
authors: Gerwick
mesh_terms: D001688:Biological Products / Q000378:metabolism*; D053898:Biosynthetic Pathways / Q000235:genetics; D016000:Cluster Analysis; D000458:Cyanobacteria / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification* / Q000378:metabolism; D004269:DNA, Bacterial / Q000737:chemistry / Q000235:genetics; D004275:DNA, Ribosomal / Q000737:chemistry / Q000235:genetics; D008853:Microscopy; D008969:Molecular Sequence Data; D010453:Peptide Synthases / Q000235:genetics; D010788:Photosynthesis; D010802:Phylogeny; D010860:Pigments, Biological / Q000378:metabolism; D048630:Polyketide Synthases / Q000235:genetics; D012336:RNA, Ribosomal, 16S / Q000235:genetics; D012623:Seawater / Q000382:microbiology*; D017422:Sequence Analysis, DNA; D014329:Tropical Climate
chemical_list: D001688:Biological Products; D004269:DNA, Bacterial; D004275:DNA, Ribosomal; D010860:Pigments, Biological; D012336:RNA, Ribosomal, 16S; D048630:Polyketide Synthases; D010453:Peptide Synthases; C104385:non-ribosomal peptide synthase