title: Velopharyngeal, speech and dental characteristics as diagnostic aids in 22q11.2 deletion syndrome.
abstract: This study examines velopharyngeal, speech, and dental parameters as possible diagnostic aids in 22q11.2 deletion syndrome. It is a retrospective study on 56 individuals. Twenty-one percent had a submucous cleft palate and 41 percent required palate surgery for speech. Common dental findings included poor oral hygiene, multiple carious lesions, congenitally missing teeth, class II malocclusion, and open bite.There are common findings that can aid the dental practitioner in recognizingthe syndrome and make appropriate referrals.
authors: Center for Craniofacial Anomalies, Department of Orofacial Sciences, University of California, San Francisco, School of Dentistry, 94143-044, USA.
authors: Snehlata
authors: S
authors: Oberoi
authors: Linda
authors: L
authors: Huynh
authors: Karin
authors: K
authors: Vargervik
mesh_terms: D000293:Adolescent; D000848:Anodontia / Q000209:etiology; D002508:Cephalometry; D002648:Child; D002675:Child, Preschool; D002972:Cleft Palate / Q000209:etiology*; D003731:Dental Caries / Q000150:complications; D004062:DiGeorge Syndrome / Q000150:complications / Q000175:diagnosis; D005260:Female; D006801:Humans; D007805:Language Development Disorders / Q000209:etiology*; D008297:Male; D008312:Malocclusion, Angle Class II / Q000209:etiology; D009305:Nasopharynx / Q000002:abnormalities; D024343:Open Bite / Q000209:etiology; D009910:Oral Hygiene; D012189:Retrospective Studies; D019291:Skull Base / Q000002:abnormalities; D014681:Velopharyngeal Insufficiency / Q000209:etiology*