title: The role of a high augmentation index in spontaneous intracerebral hemorrhage to prognosticate mortality.
abstract: The aim of the study was to determine the prognostic value of a high augmentation index, which was a surrogate marker of arterial stiffness in patients with spontaneous intracerebral hemorrhage. The outcome was divided into two groups in which the following data were collected in a computer running SphygmoCor CvMS software version 8.2. Logistic regression analysis was carried out among significant variables to identify an independent predictor of 6-month outcome and mortality. Sixty patients were recruited into the study. Admission Glasgow Coma Scale score (OR, 0.7; 95% CI, 0.450-0.971; P=0.035), total white cell count (OR, 1.2; 95% CI, 1.028-1.453; P=0.023) and hematoma volume (OR, 1.1; 95% CI, 1.024-1.204; P=0.011) were found to be statistically significant for identifying poor 6-month outcome in multivariate analysis. Factors independently associated with mortality were a high augmentation index (OR, 8.6; 95% CI, 1.794-40.940; P=0.007) and midline shift (OR, 7.5; 95% CI, 1.809-31.004; P=0.005). Admission Glasgow Coma Scale score, total white cell count and hematoma volume were significant predictors for poor 6-month outcome, and a high augmentation index and midline shift were predictors for 6-month mortality in this study.
authors: Department of Neurosciences, School of Medical Sciences, Universiti Sains Malaysia, Health Campus, Jalan Sultanah Zainab 2, Kubang Kerian, Kota Bharu, 16150, Kelantan, Malaysia.
authors: Lee Hock
authors: LH
authors: Keong
authors: Ab Rahman Izaini
authors: AR
authors: Ghani
authors: Mohamed Saufi
authors: MS
authors: Awang
authors: Sani
authors: S
authors: Sayuthi
authors: Badrisyah
authors: B
authors: Idris
authors: Jafri Malin
authors: JM
authors: Abdullah
mesh_terms: D000368:Aged; D002543:Cerebral Hemorrhage / Q000175:diagnosis* / Q000401:mortality*; D005260:Female; D015600:Glasgow Coma Scale; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D011446:Prospective Studies; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed