title: Candida esophagitis as the cause of swallowing disturbances in an 85-year-old patient with myasthenia gravis.
abstract: An 85-year-old man with myasthenia gravis was successfully treated with methotrexate (10 mg/week), pyridostigmine and prednisolone (0-30 mg/day) for over 10 years. Then, he developed dysphagia and lost weight. Gastroscopy revealed Candida esophagitis. The patient received nystatin for 2 weeks. Methotrexate was stopped, and immunosuppressive therapy was continued with prednisolone alone. The patient has now remained in good condition for over 1 year. Although dysphagia is a typical symptom of myasthenia gravis, swallowing disturbances should not be attributed hastily to this disease, since they may also be a complication of therapy.
authors: Department of Neurology, Georg-August University Göttingen, Göttingen, Germany.
authors: S
authors: S
authors: Ebert
authors: K-P
authors: KP
authors: Schweiger
authors: R
authors: R
authors: Nau
mesh_terms: D000368:Aged; D000935:Antifungal Agents / Q000627:therapeutic use; D002177:Candidiasis / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy; D003680:Deglutition Disorders / Q000175:diagnosis* / Q000209:etiology*; D003937:Diagnosis, Differential; D004359:Drug Therapy, Combination; D004941:Esophagitis / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy; D005773:Gastroscopy; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008297:Male; D008727:Methotrexate / Q000627:therapeutic use; D009157:Myasthenia Gravis / Q000175:diagnosis* / Q000188:drug therapy; D009761:Nystatin / Q000627:therapeutic use; D011239:Prednisolone / Q000627:therapeutic use; D011729:Pyridostigmine Bromide / Q000627:therapeutic use
chemical_list: D000935:Antifungal Agents; D007166:Immunosuppressive Agents; D009761:Nystatin; D011239:Prednisolone; D011729:Pyridostigmine Bromide; D008727:Methotrexate