title: Relationship between pulse wave velocity and carotid atherosclerosis in geriatric people.
abstract: OBJECTIVE
  To investigate the relationship between the pulse wave velocity (PWV) and angiographic carotid atherosclerosis in elderly patients.
  
  
  METHODS
  103 consecutive elderly patients were divided into two groups according to the results of cerebral angiography: carotid atherosclerosis group and normal carotid angiogram group. Basic clinical information was required by a standardized questionnaire. Carotid-femoral PWV (cfPWV) as a marker of Stiffness of artery was measured, Carotid intima media thickness (IMT) and carotid stenosis degree in angiography was evaluated. Independent-sample t test was used to evaluate the difference in cfPWV between the two groups, Bivariate associations between cfPWV and an index of extracoronary atherosclerosis (IMT and severity of stenosis) was performed.
  
  
  RESULTS
  Among 103 subjects, 55 with carotid atherosclerosis and 48 with a normal carotid angiogram, a significant difference between the two groups in IMT and PWV was found (P<0.05), and the cfPWV was significantly correlated with IMT (r = 0.3222, P = 0.0315), but not severity of carotid stenosis (r = 0.1573, P = 0.3137).
  
  
  CONCLUSIONS
  cfPWV showed a positive correlation to carotid IMT, and maybe is a potentially useful adjunctive atherosclerotic risk marker to Identify of early carotid atherosclerosis.
authors: Department of Geriatrics, Shandong University, Jinan, China.
authors: L
authors: L
authors: Shen
authors: W
authors: W
authors: Wu
authors: B
authors: B
authors: You
authors: H
authors: H
authors: Gao
authors: C
authors: C
authors: Wang
authors: Y
authors: Y
authors: Liu
mesh_terms: D000368:Aged; D001783:Blood Flow Velocity; D002339:Carotid Arteries / Q000000981:diagnostic imaging / Q000503:physiopathology*; D002340:Carotid Artery Diseases / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000503:physiopathology; D016893:Carotid Stenosis / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000503:physiopathology; D016022:Case-Control Studies; D002533:Cerebral Angiography; D016009:Chi-Square Distribution; D002681:China; D004548:Elasticity; D005260:Female; D015577:Geriatric Assessment; D006801:Humans; D008297:Male; D011237:Predictive Value of Tests; D011673:Pulsatile Flow; D012189:Retrospective Studies; D012720:Severity of Illness Index; D017539:Tunica Intima / Q000000981:diagnostic imaging; D017540:Tunica Media / Q000000981:diagnostic imaging; D014463:Ultrasonography