title: Endovascular treatment of symptomatic pulmonary sequestration.
abstract: Pulmonary sequestration is a rare congenital malformation whose origin is bronchial and arterial simultaneously and its vascularization comes from an anomalous systemic artery. Its clinical presentation includes recurrent pneumopathy in the same anatomic location of the lung and difficult to resolve or recurrent lung abscess. It is usually treated with antibiotherapy and eventual surgical resection. A 23-year-old woman with history of recurrent respiratory infections and three episodes of hemoptysis was admitted at the hospital. Computed tomography and magnetic resonance imaging confirmed diagnosis of pulmonary sequestration. The angiographic study showed the presence of three inflow arteries arising from the thoracic aorta (T10) and supplying the abnormal lung parenchyma at the base of the left hemithorax. The patient underwent endovascular treatment consisting of exclusion of the inflow vessels with Amplatzer occlusive devices and coils. Subsequent computed tomography angiogram confirmed complete infarction of the sequestration. At 7 months, the patient presented with a new episode of bronchial infection. Repeated angiography showed persistence of intermediate small nutrient branches that were treated with coil embolization. The patient is symptom-free at 41 months after this secondary procedure. Endovascular treatment of pulmonary sequestration, with selective embolization of the inflow arteries, is a very attractive minimally invasive therapeutic option, as compared with conventional surgery, and potentially less prone to associated complications.
authors: División de Cirugía, Departamento de Cirugía Vascular y Endovascular, Pontificia, Universidad Católica de Chile, Santiago, Chile. marinepolo@yahoo.com
authors: Leopoldo M
authors: LM
authors: Marine
authors: Francisco E
authors: FE
authors: Valdes
authors: Renato M
authors: RM
authors: Mertens
authors: Michel R
authors: MR
authors: Bergoeing
authors: Albrecht
authors: A
authors: Kramer
mesh_terms: D001998:Bronchopulmonary Sequestration / Q000150:complications / Q000175:diagnosis / Q000628:therapy*; D004621:Embolization, Therapeutic / Q000295:instrumentation; D057510:Endovascular Procedures / Q000295:instrumentation; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D055815:Young Adult