title: [A case of multiple gastrointestinal stromal tumors of the small intestine associated with von Recklinghausen disease].
abstract: A 63-year-old woman was admitted to our hospital because of tarry stool several years previously. At the time, café-au-lait spots and dermal nodules were found on her entire body, and a diagnosis of von Recklinghausen disease was established. Small bowel endoscopy revealed a submucosal tumor in the jejunum. Laparotomy was therefore performed on the suspicion of intestinal GIST. Numerous extramural tumors with a diameter of 3-5mm were observed along the jejunum and ileum, in addition to the primary tumor. Partial resection of the jejunum, including the primary tumor and only one small nodule was performed to prevent short bowel syndrome. Immunopathological studies of the tumors were positive for KIT and CD34 and we diagnosed multiple intestinal GISTs. Imatinib mesylate was not administered, but no growth of the residual tumors have been recognized for 10 months after surgery.
authors: Department of Surgery, Nara Medical University. shinshin@naramed-u.ac.jp
authors: Shinji
authors: S
authors: Nakamura
authors: Fumikazu
authors: F
authors: Koyama
authors: Tadashi
authors: T
authors: Nakagawa
authors: Kazuaki
authors: K
authors: Uchimoto
authors: Kenichi
authors: K
authors: Otsuki
authors: Takeshi
authors: T
authors: Ueda
authors: Naoto
authors: N
authors: Nishigori
authors: Hisao
authors: H
authors: Fujii
authors: Yoshiyuki
authors: Y
authors: Nakajima
authors: Yasunori
authors: Y
authors: Enomoto
authors: Akitaka
authors: A
authors: Nonomura
mesh_terms: D005260:Female; D046152:Gastrointestinal Stromal Tumors / Q000150:complications*; D006801:Humans; D007078:Ileal Neoplasms / Q000150:complications* / Q000628:therapy; D007580:Jejunal Neoplasms / Q000150:complications* / Q000628:therapy; D008875:Middle Aged; D009456:Neurofibromatosis 1 / Q000150:complications*