title: [Extraesophageal reflux. Overview and discussion of a new method for pH monitoring].
abstract: BACKGROUND
  Extraesophageal reflux disease often requires diagnosis and treatment by a phoniatry or ear, nose and throat specialist. The disease needs to be differentiated from gastroesophageal reflux disease.
  
  
  OBJECTIVE
  A new oropharyngeal pH measuring system with a single channel probe has recently been introduced. The aim of this study was to compare oropharyngeal pH-metry with the existing diagnostic methods for extraesophageal reflux disease and to present initial results in our own patients.
  
  
  METHODS
  A literature search for oropharyngeal pH-metry was performed in the databases NHS EED, HTA, DARE, Clinical trials, Cochrane reviews and Medline/PubMed. A selective literature search was also carried out on the problem of extraesophageal reflux disease.
  
  
  RESULTS
  Evaluation scales, trial proton pump inhibitor therapy or pH-metry, for example, can be used to diagnose extraesophageal reflux disease. pH-metry can be performed using a classical two-channel pH-metry system; a new oropharyngeal pH measuring system has recently been introduced. This new method has been evaluated in initial studies for normative data and has been compared to two-channel pH-metry. Prospective randomised studies to diagnose extraesophageal reflux disease with the new oropharyngeal pH-metry method are still lacking.
  
  
  CONCLUSIONS
  Oropharyngeal pH-metry has some potential advantages compared to classical two-channel pH-metry; however, a lot of questions remain unanswered. These will be discussed and illustrated with the help of a number of own patient case reports.
authors: Klinik und Poliklinik für Phoniatrie und Pädaudiologie, Medizinische Hochschule Hannover, Carl-Neuberg-Str. 1, 30625, Hannover, Deutschland. jungheim.michael@mh-hannover.de
authors: M
authors: M
authors: Jungheim
authors: M
authors: M
authors: Ptok
mesh_terms: D002940:Circadian Rhythm / Q000502:physiology; D003299:Cooperative Behavior; D003937:Diagnosis, Differential; D004867:Equipment Design; D050782:Esophageal pH Monitoring / Q000295:instrumentation*; D005744:Gastric Acid / Q000502:physiology; D005764:Gastroesophageal Reflux / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology; D006801:Humans; D033183:Interdisciplinary Communication; D057045:Laryngopharyngeal Reflux / Q000175:diagnosis* / Q000188:drug therapy / Q000503:physiopathology; D007828:Laryngoscopy; D010434:Pepsin A / Q000502:physiology; D054328:Proton Pump Inhibitors / Q000627:therapeutic use; D012815:Signal Processing, Computer-Assisted / Q000295:instrumentation
chemical_list: D054328:Proton Pump Inhibitors; D010434:Pepsin A