title: A histological study of pulp reaction to various water/powder ratios of white mineral trioxide aggregate as pulp-capping material in human teeth: a double-blinded, randomized controlled trial.
abstract: OBJECTIVE
  To compare the histological pulp reaction to various water/powder ratios of white mineral trioxide aggregate (MTA) as a pulp-capping material in healthy human teeth.
  
  
  METHODS
  Twenty-nine disease-free maxillary and mandibular third molar teeth, scheduled for extraction, were exposed mechanically and then capped with 0.28, 0.33 and 0.40 water/powder ratios of white MTA (ProRoot; Dentsply Maillefer, Ballaigues, Switzerland) and restored with glass ionomer. After 30 days, the teeth were extracted, resected apically and immersed in 10% formalin. For histological processing, the teeth were sectioned buccolingually in 5-μm-thick slices, stained with Haematoxylin and Eosin and evaluated by a light microscope. Samples were evaluated for intensity and type of inflammation, presence of necrosis, as well as continuity, morphology and thickness of calcified bridges. The data were analysed by Kruskal-Wallis and Mann-Whitney tests.
  
  
  RESULTS
  There were no significant differences in the diameter, morphology and continuity of the calcified bridges, intensity and type of inflammation or presence of necrosis (P > 0.05) in the pulps covered by MTA with various water/powder ratios. Two teeth failed to display a calcified bridge, and one had a pulp necrosis.
  
  
  CONCLUSIONS
  Water-to-powder ratios of MTA had no significant influence on the histological outcome of direct pulp capping on healthy pulps.
authors: Kerman Oral and Dental Diseases Research Center, Kerman University of Medical Sciences, Kerman, Iran. arashahravan@gmail.com
authors: A
authors: A
authors: Shahravan
authors: S P
authors: SP
authors: Jalali
authors: M
authors: M
authors: Torabi
authors: A A
authors: AA
authors: Haghdoost
authors: H
authors: H
authors: Gorjestani
mesh_terms: D017607:Aluminum Compounds / Q000494:pharmacology*; D017610:Calcium Compounds / Q000494:pharmacology*; D003782:Dental Pulp / Q000033:anatomy & histology / Q000187:drug effects*; D003785:Dental Pulp Capping / Q000379:methods*; D004305:Dose-Response Relationship, Drug; D004338:Drug Combinations; D006801:Humans; D008334:Mandible; D008437:Maxilla; D008964:Molar, Third; D010087:Oxides / Q000494:pharmacology*; D057872:Pulp Capping and Pulpectomy Agents / Q000494:pharmacology*; D012016:Reference Values; D017640:Silicates / Q000494:pharmacology*; D055815:Young Adult
chemical_list: D017607:Aluminum Compounds; D017610:Calcium Compounds; D004338:Drug Combinations; D010087:Oxides; D057872:Pulp Capping and Pulpectomy Agents; D017640:Silicates; C086631:mineral trioxide aggregate