title: Direct amidation of azoles with formamides via metal-free C-H activation in the presence of tert-butyl perbenzoate.
abstract: A novel and simple method for the direct amidation of azoles with formamides has been developed. The reaction could occur smoothly in the presence of tert-butyl perbenzoate (TBPB) as an oxidant under metal- and base-free conditions. Direct dehydrogenative cross-coupling of formamides and azoles generated the corresponding products in good yields.
authors: Department of Chemistry, Huaibei Normal University, Huaibei, Anhui 235000, PR China.
authors: Tao
authors: T
authors: He
authors: Hongji
authors: H
authors: Li
authors: Pinhua
authors: P
authors: Li
authors: Lei
authors: L
authors: Wang
mesh_terms: D001393:Azoles / Q000737:chemistry*; D001565:Benzoates / Q000737:chemistry*; D002244:Carbon / Q000737:chemistry; D005559:Formamides / Q000737:chemistry*; D006859:Hydrogen / Q000737:chemistry; D008670:Metals / Q000737:chemistry
chemical_list: D001393:Azoles; D001565:Benzoates; D005559:Formamides; D008670:Metals; D002244:Carbon; D006859:Hydrogen; C017611:peroxybenzoic acid