title: Socioecological influences on community involvement in HIV vaccine research.
abstract: OBJECTIVE
  This study investigated socioecological factors influencing HIV vaccine research participation among communities living in geographic areas with high HIV prevalence and high poverty rates.
  
  
  METHODS
  We surveyed a sample of 453 adults ≤18 years from areas of high poverty and high HIV prevalence in metro Atlanta and differentiated the effects of individual-, social/organizational-, and community-level characteristics on participation in HIV vaccine research via multilevel modeling techniques that incorporated questionnaire, program, and census data.
  
  
  RESULTS
  Models that adjusted for both individual-level covariates (such as race, gender, attitudes, and beliefs concerning HIV research), social/organizational- and community-level factors such as local HIV prevalence rates, revealed that the extent of HIV prevention-related programs and services in census tracts contributed to individuals' likelihood of participation in an HIV vaccine study. Additionally, neighborhood-based organizations offering HIV medical and treatment programs, support groups, and services (e.g., food, shelter, and clothing) encourage greater HIV vaccine research participation.
  
  
  CONCLUSIONS
  The findings support the hypothesis that community-level factors facilitate participation in HIV vaccine research independent of both individual- and social/organizational-level factors.
authors: Emory University School of Medicine, Department of Medicine, Division of Infectious Diseases, GA, United States. pfrew@emory.edu
authors: Paula M
authors: PM
authors: Frew
authors: Matthew
authors: M
authors: Archibald
authors: Brooke
authors: B
authors: Hixson
authors: Carlos
authors: C
authors: del Rio
mesh_terms: D016915:AIDS Vaccines / Q000276:immunology*; D000293:Adolescent; D000328:Adult; D001294:Attitude to Health; D019058:Community Networks / Q000458:organization & administration*; D003256:Community Participation; D005006:Ethnicity / Q000523:psychology; D005260:Female; D005845:Georgia / Q000453:epidemiology; D015658:HIV Infections / Q000453:epidemiology / Q000517:prevention & control*; D006801:Humans; D007182:Income; D008297:Male; D008875:Middle Aged; D009042:Motivation; D015995:Prevalence; D012931:Social Environment; D011795:Surveys and Questionnaires; D055815:Young Adult
chemical_list: D016915:AIDS Vaccines