title: Microfluidic technologies for synthetic biology.
abstract: Microfluidic technologies have shown powerful abilities for reducing cost, time, and labor, and at the same time, for increasing accuracy, throughput, and performance in the analysis of biological and biochemical samples compared with the conventional, macroscale instruments. Synthetic biology is an emerging field of biology and has drawn much attraction due to its potential to create novel, functional biological parts and systems for special purposes. Since it is believed that the development of synthetic biology can be accelerated through the use of microfluidic technology, in this review work we focus our discussion on the latest microfluidic technologies that can provide unprecedented means in synthetic biology for dynamic profiling of gene expression/regulation with high resolution, highly sensitive on-chip and off-chip detection of metabolites, and whole-cell analysis.
authors: School of Nano-Bioscience and Chemical Engineering, Ulsan National Institute of Science and Technology, 100 Banyeon-ri, Ulsan 689-798, Korea; E-Mails: vinu23pari@unist.ac.kr (P.V.); wjdals24@unist.ac.kr (J.M.P.).
authors: Parisutham
authors: P
authors: Vinuselvi
authors: Seongyong
authors: S
authors: Park
authors: Minseok
authors: M
authors: Kim
authors: Jung Min
authors: JM
authors: Park
authors: Taesung
authors: T
authors: Kim
authors: Sung Kuk
authors: SK
authors: Lee
mesh_terms: D019295:Computational Biology; D005434:Flow Cytometry; D005786:Gene Expression Regulation; D006801:Humans; D055432:Metabolomics; D046228:Microarray Analysis; D046210:Microfluidic Analytical Techniques; D008904:Miniaturization; D058615:Synthetic Biology / Q000379:methods*