title: Coblation-assisted endonasal endoscopic resection of juvenile nasopharyngeal angiofibroma.
abstract: OBJECTIVE
  Juvenile nasopharyngeal angiofibroma may be successfully resected using endoscopic techniques. However, the use of coblation technology for such resection has not been described. This study aimed to document cases of Fisch class I juvenile nasopharyngeal angiofibroma with limited nasopharyngeal and nasal cavity extension, which were completely resected using an endoscopic coblation technique.
  
  
  METHODS
  We retrospectively studied 23 patients with juvenile nasopharyngeal angiofibroma who underwent resection with either traditional endoscopic instruments (n = 12) or coblation (n = 11). Intra-operative blood loss and overall operative time were recorded.
  
  
  RESULTS
  The mean tumour resection time for coblation and traditional endoscopic instruments was 87 and 136 minutes, respectively (t = 9.962, p < 0.001). Mean intra-operative blood loss was 121 and 420 ml, respectively (t = 28.944, p < 0.001), a significant difference. Both techniques achieved complete tumour resection with minimal damage to adjacent tissues, and no recurrence in any patient.
  
  
  CONCLUSIONS
  Coblation successfully achieves transnasal endoscopic resection of juvenile nasopharyngeal angiofibroma (Fisch class I), with good surgical margins and minimal blood loss.
authors: Department of Otolaryngology, Zhongnan Hospital of Wuhan University, Hubei, People's Republic of China. Yelinfeng69@163.com
authors: L
authors: L
authors: Ye
authors: X
authors: X
authors: Zhou
authors: J
authors: J
authors: Li
authors: J
authors: J
authors: Jin
mesh_terms: D000293:Adolescent; D018322:Angiofibroma / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D016063:Blood Loss, Surgical / Q000706:statistics & numerical data; D017115:Catheter Ablation / Q000295:instrumentation / Q000379:methods; D004724:Endoscopy; D004844:Epistaxis / Q000209:etiology; D006488:Hemostasis, Surgical / Q000379:methods; D006801:Humans; D008297:Male; D015508:Nasal Obstruction / Q000209:etiology; D009303:Nasopharyngeal Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D012189:Retrospective Studies; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome