title: Immunology of paracoccidioidomycosis.
abstract: Paracoccidioidomycosis is the most prevalent systemic mycosis in Latin America, among immunecompetent patients. It's caused by the dimorphic fungus Paracoccidioiddes brasiliensis. Investigations regarding its immunopathogenesis are very important in the understanding of aspects related to natural history, as the protective immunity, and the relationship between host and parasite; also favoring the knowledge about clinical patterns and the elaboration of therapeutic strategies. The disease clinical polymorphism depends, at least, of the immune response profile according to the tissue and blood released citokynes, resulting in tissue damage.
authors: chool of Medicine, Sao Paulo State University (Unesp) - Botucatu (SP), Brazil.
authors: Maria Rita Parise
authors: MR
authors: Fortes
authors: Hélio Amante
authors: HA
authors: Miot
authors: Cilmery Suemi
authors: CS
authors: Kurokawa
authors: Mariângela Esther Alencar
authors: ME
authors: Marques
authors: Sílvio Alencar
authors: SA
authors: Marques
mesh_terms: D000208:Acute Disease; D002908:Chronic Disease; D016207:Cytokines / Q000276:immunology*; D054884:Host-Pathogen Interactions / Q000502:physiology; D006801:Humans; D010228:Paracoccidioides / Q000276:immunology / Q000502:physiology*; D010229:Paracoccidioidomycosis / Q000276:immunology* / Q000473:pathology; D012720:Severity of Illness Index
chemical_list: D016207:Cytokines