title: S-alkylation of thiacalixarenes: a long-neglected possibility in the calixarene family.
abstract: Despite the high nucleophilicity of sulfur atoms, thiacalixarenes have been alkylated only on oxygen atoms thus far. Using strong alkylating agents (triflates, trialkyloxonium salts), the substitution of the sulfur bridges has been successfully accomplished. The corresponding sulfonium salts of thiacalix[4]arene are formed regio- and stereoselectively as a completely new type of substitution pattern in thiacalixarene chemistry. These compounds possess interesting conformational behavior and could be used as unusual alkylating agents with uncommon selectivity.
authors: Department of Organic Chemistry, Prague Institute of Chemical Technology, Technicka 6, 166 28 Prague 6, Czech Republic.
authors: Ondrej
authors: O
authors: Kundrat
authors: Vaclav
authors: V
authors: Eigner
authors: Hana
authors: H
authors: Dvorakova
authors: Pavel
authors: P
authors: Lhotak