title: Is hyperhomocysteinemia relevant in patients with celiac disease?
abstract: OBJECTIVE
  To investigate whether this might be related to the presence of hyperhomocysteinemia.
  
  
  METHODS
  From January 1998 to December 2008, we evaluated the presence of hyperhomocysteinemia in a series of 165 adult celiac disease (CD) patients (138 females and 27 males, mean age 43 years).
  
  
  RESULTS
  Hyperhomocysteinemia was evident in 32 patients (19.3%), although most of them had moderate levels (mean value 25 mcg/ml; range 15-30). Only one patient had a history of myocardial infarction (heterozygosis for N5-N10-metil tetrahydrofolate reductase mutation).
  
  
  CONCLUSIONS
  The systematic assessment of hyperhomocysteinemia seems, at present, unjustified in CD patients.
authors: Division of Internal Medicine, Desio General Hospital, 20033 Desio, Italy.
authors: Giovanni
authors: G
authors: Casella
authors: Gabrio
authors: G
authors: Bassotti
authors: Vincenzo
authors: V
authors: Villanacci
authors: Camillo
authors: C
authors: Di Bella
authors: Fabio
authors: F
authors: Pagni
authors: Gian Luigi
authors: GL
authors: Corti
authors: Giuseppe
authors: G
authors: Sabatino
authors: Mara
authors: M
authors: Piatti
authors: Vittorio
authors: V
authors: Baldini
mesh_terms: D000328:Adult; D000368:Aged; D002446:Celiac Disease / Q000453:epidemiology* / Q000473:pathology / Q000503:physiopathology; D015897:Comorbidity; D005260:Female; D006801:Humans; D020138:Hyperhomocysteinemia / Q000453:epidemiology* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D055815:Young Adult