title: New biomarkers for acute renal injury.
abstract: Incidence of acute kidney injury (AKI) is increasing rapidly to epidemic proportions. Development of AKI, especially in intensive care settings, is associated with increased morbidity, mortality and hospitalization costs. Currently available diagnostic tools are mostly insensitive for early diagnosis, however prompt diagnosis and risk stratification are necessary for guiding therapy and preventing progression of disease. Finding an early, reliable, suitable, easily reproducible, economical and accurate biomarker for AKI is a top research priority. In recent years, many urinary and serum proteins have been investigated as possible early markers of AKI and some of them have shown great promise. This topic reviews some of the emerging biomarkers of AKI.
authors: Manik Hospital and Research Centre, Aurangabad, India.
authors: Sachin S
authors: SS
authors: Soni
authors: JJ Hospital, Mumbai, India.
authors: Rupesh
authors: R
authors: Pophale
authors: Department of Nephrology, Dialysis and Transplantation, International Renal Research Institute, Vicenza (IRRIV), Italy.
authors: Claudio
authors: C
authors: Ronco
mesh_terms: D058186:Acute Kidney Injury / Q000175:diagnosis* / Q000401:mortality; D000209:Acute-Phase Proteins / Q000652:urine; D015415:Biomarkers / Q000032:analysis* / Q000097:blood / Q000652:urine; D042241:Early Diagnosis; D050556:Fatty Acid-Binding Proteins / Q000097:blood / Q000652:urine; D000072596:Hepatitis A Virus Cellular Receptor 1; D006801:Humans; D020382:Interleukin-18 / Q000652:urine; D000071068:Lipocalin-2; D054834:Lipocalins / Q000097:blood / Q000652:urine; D008562:Membrane Glycoproteins / Q000097:blood / Q000652:urine; D011518:Proto-Oncogene Proteins / Q000097:blood / Q000652:urine; D011991:Receptors, Virus / Q000097:blood
chemical_list: D000209:Acute-Phase Proteins; D015415:Biomarkers; C493319:FABP1 protein, human; D050556:Fatty Acid-Binding Proteins; C491143:HAVCR1 protein, human; D000072596:Hepatitis A Virus Cellular Receptor 1; D020382:Interleukin-18; C489506:LCN2 protein, human; D000071068:Lipocalin-2; D054834:Lipocalins; D008562:Membrane Glycoproteins; D011518:Proto-Oncogene Proteins; D011991:Receptors, Virus