title: How the Orthopedic Foundation for Animals (OFA) is tackling inherited disorders in the USA: using hip and elbow dysplasia as examples.
abstract: The Orthopedic Foundation for Animals (OFA) maintains an on-line health pedigree database for inherited disorders of animals. With the American Kennel Club Canine Health Foundation, the OFA maintains the Canine Health Information Center (CHIC) for parent breed clubs to identify breed-specific required health tests. Analysis of the results of OFA evaluations in the hip and elbow registries show that selection based on phenotype improves conformation. Disorders with complex inheritance respond best to selection based on depth (ancestors) and breadth (siblings) of pedigree health test results. This information can be derived from vertical pedigrees generated on the OFA website.
authors: Orthopedic Foundation for Animals, Columbia, MO 65201-3806, USA. ofa@offa.org
authors: G Gregory
authors: GG
authors: Keller
authors: Edmund
authors: E
authors: Dziuk
authors: Jerold S
authors: JS
authors: Bell
mesh_terms: D000818:Animals; D001947:Breeding; D016208:Databases, Factual; D004283:Dog Diseases / Q000235:genetics*; D004285:Dogs; D004551:Elbow Joint / Q000002:abnormalities*; D030342:Genetic Diseases, Inborn / Q000235:genetics / Q000662:veterinary*; D006619:Hip Dysplasia, Canine / Q000235:genetics*; D009985:Orthopedics / Q000662:veterinary; D010375:Pedigree; D014481:United States