title: Effect of reduced heifer nutrition during in utero and post-weaning development on glucose and acetate kinetics.
abstract: Energetic efficiency was evaluated in composite bred heifers born from dams receiving 1·8 or 1·2 kg/d winter supplementation for approximately 80 d before parturition. Heifers were then developed post-weaning and randomly assigned to heifer development treatments of either control (100 %; ad libitum; n 8/year) or restricted (80 %; fed 80 % of supplementation fed to controls adjusted to a common body weight: n 8/year) in a 2-year study. A glucose tolerance test (GTT) and acetate irreversible loss test (AILT) were administered to heifers at the termination of a 140 d development period when the heifers were approximately 403 d of age and consumed a silage-based diet, and again at 940 d of age when pregnant with their second calf and grazing dormant forage. No differences were measured (P>0·08) for dam winter nutrition or heifer development treatment for baseline serum metabolites or measures in either the GTT or the AILT. However, changes in baseline serum concentrations (P>0·05) were different between metabolic challenges, which occurred at different stages of development. No difference in acetate disappearance (P = 0·18) and half-life (P = 0·66) was measured between the two metabolic challenges. A trend for glucose half-life to be shorter in heifers born from dams receiving in utero winter treatments that supplied 1·2 kg/d of winter supplementation was observed (P = 0·083). Heifers developed with lower total DM intake during a 140 d development period had similar glucose and acetate incorporation rates as ad libitum-fed heifers when evaluated at two different production stages.
authors: Fort Keogh Livestock and Range Research Laboratory, United States Department of Agriculture - Agricultural Research Service, Miles City, MT 59301, USA. richard.waterman@ars.usda.gov
authors: Richard C
authors: RC
authors: Waterman
authors: Andrew J
authors: AJ
authors: Roberts
authors: Thomas W
authors: TW
authors: Geary
authors: Elaine E
authors: EE
authors: Grings
authors: Leeson J
authors: LJ
authors: Alexander
authors: Michael D
authors: MD
authors: MacNeil
mesh_terms: D000085:Acetates / Q000378:metabolism*; D000818:Animals; D001786:Blood Glucose / Q000378:metabolism*; D002417:Cattle; D004734:Energy Metabolism; D005260:Female; D006207:Half-Life; D009752:Nutritional Status; D011247:Pregnancy; D014886:Weaning
chemical_list: D000085:Acetates; D001786:Blood Glucose