title: The metabolic fate of isocombretastatin A-4 in human liver microsomes: identification, synthesis and biological evaluation of metabolites.
authors: Univ Paris-Sud, Faculté de Pharmacie, CNRS, BioCIS-UMR 8076, Laboratoire de Chimie Thérapeutique, 5 Rue J.-B. Clément, Châtenay-Malabry 92296, France.
authors: Mohamed Ali
authors: MA
authors: Soussi
authors: Silvio
authors: S
authors: Aprile
authors: Samir
authors: S
authors: Messaoudi
authors: Olivier
authors: O
authors: Provot
authors: Erika
authors: E
authors: Del Grosso
authors: Jérôme
authors: J
authors: Bignon
authors: Joëlle
authors: J
authors: Dubois
authors: Jean-Daniel
authors: JD
authors: Brion
authors: Giorgio
authors: G
authors: Grosa
authors: Mouad
authors: M
authors: Alami
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000138:chemical synthesis / Q000378:metabolism* / Q000494:pharmacology; D045744:Cell Line, Tumor; D006801:Humans; D006900:Hydroxylation; D007536:Isomerism; D008862:Microsomes, Liver / Q000378:metabolism*; D013267:Stilbenes / Q000737:chemistry / Q000378:metabolism* / Q000494:pharmacology; D014404:Tubulin / Q000187:drug effects; D050257:Tubulin Modulators / Q000138:chemical synthesis / Q000378:metabolism* / Q000494:pharmacology
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D013267:Stilbenes; D014404:Tubulin; D050257:Tubulin Modulators; C058728:fosbretabulin