title: [Experimental quality assessment of APTT-control reagent kits in the study of heparin-containing plasma in therapeutic ranges].
abstract: Investigation of activated partial thromboplastin time (APTT) in the plasma samples containing different levels of heparin determines the following parameters of the quality of APTT-control reagent kits: coefficient of variation, linearity, sensitivity, and detection. The kit is shown to meet GOST P 51352-99 requirements. The determination of the validity coefficient of approximation has proven a directly proportional functional relationship of the APTT values to the level of heparin in therapeutic ranges in the logarithmic coordinate system. The kit may be used to monitor heparin therapy.
authors: N N
authors: NN
authors: Staritsyna
authors: A I
authors: AI
authors: Shanskaia
authors: L P
authors: LP
authors: Papaian
authors: R P
authors: RP
authors: Ivanova
mesh_terms: D001778:Blood Coagulation Disorders / Q000097:blood* / Q000188:drug therapy; D005240:Feasibility Studies; D006493:Heparin / Q000097:blood* / Q000627:therapeutic use; D006801:Humans; D008991:Monitoring, Physiologic; D010314:Partial Thromboplastin Time / Q000379:methods / Q000592:standards*; D011785:Quality Assurance, Health Care; D011933:Reagent Kits, Diagnostic / Q000592:standards*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
chemical_list: D011933:Reagent Kits, Diagnostic; D006493:Heparin