title: Mitral annuloplasty for dilated cardiomyopathy with mitral regurgitation.
abstract: OBJECTIVE
  This study reports survival, functional status, the change in post-operative left ventricular dimensions and function after'undersized mitral annuloplasty' in patients with non-ischaemic non-valvular dilated cardiomyopathy and secondary mitral regurgitation.
  
  
  METHODS
  Between 2003 and 2009 10 patients (mean age 61.5 +/- 14 years) with non-ischaemic, non-valvular dilated cardiomyopathy with left ventricular ejection fraction (LV EF) <40% (mean +/- SD, 30.7 +/- 5.27) underwent isolated mitral repair and annuloplasty. All patients were receiving maximal drug therapy. Preoperatively 1 patient (10%) was functioning in New York Heart Association (NYHA) class II, 8 patients (80%) in class III and 1 patient (10%) in class IV. Transthoracic echocardiography was performed immediately before surgery and one year after surgery to assess valvular and ventricular function. For statistical analysis we have used paired t-tests and Wilcoxon's rank test.
  
  
  RESULTS
  There were no hospital deaths. Duration of intubation and ICU stay was 1.8 +/- 1.3 and 3.8 +/- 1.8 days, respectively. Functional class after one year was significantly better than the preoperative value (from 3.00 +/- 0.47 to 1.40 +/- 0.52, P<0.001). One year post-operative data showed significant improvement of LV EF (from 30.70 +/- 5.27 to 46.60 +/- 14.47%) and a decrease of the left ventricular diastolic dimension (LVDd) (from 59.30 +/- 5.62 to 50.70 +/- 6.04 mm).
  
  
  CONCLUSIONS
  Isolated undersized mitral annuloplasty in patients with non-ischaemic non-valvular dilated cardiomyopathy with associated mitral regurgitation, is a safe method with the potential of improving functional class, LV EF, and LVDd after one year.
authors: Department of Intensive Care, University Hospitals Leuven, Leuven, Belgium. tomsarens@hotmail.com
authors: Tom
authors: T
authors: Sarens
authors: Paul
authors: P
authors: Herijgers
authors: Hadewich
authors: H
authors: Hermans
authors: Marie-Christine
authors: MC
authors: Herregods
mesh_terms: D000328:Adult; D000368:Aged; D058385:Cardiac Valve Annuloplasty; D002311:Cardiomyopathy, Dilated / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000401:mortality / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve / Q000601:surgery*; D008944:Mitral Valve Insufficiency / Q000453:epidemiology; D012189:Retrospective Studies; D013318:Stroke Volume; D014463:Ultrasonography