title: Primary prevention of CVD: diet.
abstract: BACKGROUND
  Diet is important in the cause of many chronic diseases. Individual change in dietary behaviour has the potential to decrease the burden of chronic disease, particularly cardiovascular disease (CVD).
  
  
  METHODS
  We conducted a systematic review and aimed to answer the following clinical question: What are the effects of dietary advice in generally healthy adults without existing CVD or increased CVD risk factors to improve cardiovascular outcomes (mortality, cardiovascular events, and cardiovascular risk factors)? We searched: Medline, Embase, The Cochrane Library, and other important databases up to April 2010 (Clinical Evidence reviews are updated periodically, please check our website for the most up-to-date version of this review). We included harms alerts from relevant organisations such as the US Food and Drug Administration (FDA) and the UK Medicines and Healthcare products Regulatory Agency (MHRA).
  
  
  RESULTS
  We found 14 systematic reviews or RCTs that met our inclusion criteria. We performed a GRADE evaluation of the quality of evidence for interventions.
  
  
  CONCLUSIONS
  In this systematic review we present information relating to the effectiveness and safety of the following interventions: advice to increase fibre intake alone, advice to increase fruit and vegetable intake alone, advice to reduce and/or modify fat intake alone, and advice to reduce sodium intake alone.
authors: Oxford Radcliffe Hospitals NHS Trust, Oxford, UK.
authors: Hermione Clare
authors: HC
authors: Price
authors: Rebecca K
authors: RK
authors: Simmons
mesh_terms: D002318:Cardiovascular Diseases / Q000517:prevention & control; D004032:Diet; D019317:Evidence-Based Medicine; D005247:Feeding Behavior; D006801:Humans; D015994:Incidence; D008019:Life Style; D011322:Primary Prevention; D012307:Risk Factors