title: Influence of internal optical astigmatism on the correction of myopic astigmatism by LASIK.
abstract: OBJECTIVE
  To investigate the influence of the origin of astigmatism on the correction of myopic astigmatism by LASIK.
  
  
  METHODS
  A retrospective study was conducted of the records of 192 patients (192 eyes) undergoing LASIK for correction of myopia and myopic astigmatism from January to September 2010. Ocular residual astigmatism (ORA) and lenticular astigmatism (LA) were determined by vector analysis using objective refraction and Pentacam (Oculus Optikgeräte GmbH) imaging of both corneal surfaces. Patients were divided into two groups according to ORA (high ORA group: ORA/preoperative refractive astigmatism >1; normal ORA group: ORA/preoperative refractive astigmatism ≤ 1) and LA (high LA group: LA/preoperative refractive astigmatism >1; normal LA group: LA/preoperative refractive astigmatism ≤ 1). Procedural efficacy was compared between those eyes with and without a significant amount of internal optical astigmatism using index of success.
  
  
  RESULTS
  Mean preoperative vectors for the astigmatism of the anterior cornea, posterior cornea, and lens were -1.33 × 3.0°, -0.33 × 95.3°, and -0.27 × 103.3°, respectively. Mean indices of success in the high and low ORA groups were 1.75 and 0.59, respectively (t=7.81, P<.001). Mean indices of success in the high and low LA groups were 2.07 and 0.70, respectively (t=12.36, P<.001). The higher indices of success in the high ORA and high LA groups suggest a lower efficacy of LASIK in treating astigmatism primarily located intraocularly.
  
  
  CONCLUSIONS
  Myopic LASIK is less effective in correcting astigmatism when astigmatism is mainly located at the internal optics. Topography and refractive value should be incorporated in the treatment of patients when a significant amount of internal optical astigmatism is detected preoperatively.
authors: Department of Ophthalmology, Eye, Ear, Nose and Throat Hospital, Fudan University Shanghai Medical College, China.
authors: Yi-Shan
authors: YS
authors: Qian
authors: Jia
authors: J
authors: Huang
authors: Rui
authors: R
authors: Liu
authors: Ren-Yuan
authors: RY
authors: Chu
authors: Ye
authors: Y
authors: Xu
authors: Xing-Tao
authors: XT
authors: Zhou
authors: Matthew R
authors: MR
authors: Hoffman
mesh_terms: D000293:Adolescent; D000328:Adult; D001251:Astigmatism / Q000503:physiopathology*; D003315:Cornea / Q000503:physiopathology*; D005260:Female; D006801:Humans; D020731:Keratomileusis, Laser In Situ; D054018:Lasers, Excimer / Q000627:therapeutic use*; D007908:Lens, Crystalline / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D009216:Myopia / Q000503:physiopathology / Q000601:surgery*; D012029:Refraction, Ocular / Q000502:physiology; D012189:Retrospective Studies; D016896:Treatment Outcome; D014792:Visual Acuity / Q000502:physiology; D055815:Young Adult