title: Distribution of malassezia species on the scalp in korean seborrheic dermatitis patients.
abstract: BACKGROUND
  Malassezia species play an important role in the pathogenesis of seborrheic dermatitis. In particular, M. restricta and M. globosa are considered to be the predominant organisms in seborrheic dermatitis of Western countries. However, species distribution of Malassezia in seborrheic dermatitis has not been clearly determined yet in Asia.
  
  
  OBJECTIVE
  To identify the distribution of Malassezia species on the scalp of seborrheic dermatitis patients in Korea using 26S rDNA PCR-RFLP analysis.
  
  
  METHODS
  A total of 40 seborrheic dermatitis patients and 100 normal healthy volunteers were included in this study. For the identification of Malassezia species, the scalp scales of the subjects were analyzed by 26S rDNA PCR-RFLP analysis.
  
  
  RESULTS
  The most commonly identified Malassezia species were M. restricta in the seborrheic dermatitis patients, and M. globosa in the normal controls. In the seborrheic dermatitis group, M. restricta was identified in 47.5%, M. globosa in 27.5%, M. furfur in 7.5%, and M. sympodialis in 2.5% of patients. In the healthy control group, M. globosa was identified in 32.0%, M. restricta in 25.0%, M. furfur in 8.0%, M. obtusa in 6.0%, M. slooffiae in 6.0%, and M. sympodialis in 4.0% of subjects.
  
  
  CONCLUSIONS
  M. restricta is considered to be the most important Malassezia species in Korean seborrheic dermatitis patients.
authors: Department of Dermatology, Konkuk University College of Medicine, Seoul, Korea.
authors: Yang Won
authors: YW
authors: Lee
authors: Hee Jin
authors: HJ
authors: Byun
authors: Beom Joon
authors: BJ
authors: Kim
authors: Dong Ha
authors: DH
authors: Kim
authors: Yun Young
authors: YY
authors: Lim
authors: Jin Woong
authors: JW
authors: Lee
authors: Myeung Nam
authors: MN
authors: Kim
authors: Donghak
authors: D
authors: Kim
authors: Young-Jin
authors: YJ
authors: Chun
authors: Seog Kyun
authors: SK
authors: Mun
authors: Chan Woong
authors: CW
authors: Kim
authors: Sung Eun
authors: SE
authors: Kim
authors: Jae Sung
authors: JS
authors: Hwang