title: Isolation of pure disubstituted E olefins through Mo-catalyzed Z-selective ethenolysis of stereoisomeric mixtures.
abstract: Monoaryloxide-pyrrolide (MAP) complexes of molybdenum were employed for the selective ethenolysis of 1,2-disubstituted Z olefins in the presence of the corresponding E olefins. Reactions were performed in the presence of 0.02-3.0 mol % catalyst at 22 °C under 20 atm ethylene. We have demonstrated that the Z isomer of an easily accessible E:Z mixture can be destroyed through ethenolysis and the E alkene thereby isolated readily in high yield and exceptional stereoisomeric purity.
authors: Department of Chemistry 6-331, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.
authors: Smaranda C
authors: SC
authors: Marinescu
authors: Daniel S
authors: DS
authors: Levine
authors: Yu
authors: Y
authors: Zhao
authors: Richard R
authors: RR
authors: Schrock
authors: Amir H
authors: AH
authors: Hoveyda
mesh_terms: D000475:Alkenes / Q000138:chemical synthesis / Q000737:chemistry / Q000302:isolation & purification*; D002384:Catalysis; D015394:Molecular Structure; D008982:Molybdenum / Q000737:chemistry*; D009942:Organometallic Compounds / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000475:Alkenes; D009942:Organometallic Compounds; D008982:Molybdenum