title: [A case of antiphospholipid syndrome in course of pregnancy and puerperium with lupus-like disease suspicion].
abstract: The antiphospholipid syndrome (APS) is a systemic non-inflammatory and autoimmune connective tissue disease. ASP is characterized by formation of autoantibodies against cell membrane phospholipids which act as procaogulation factors. Association with recurrent pregnancy loss, intrauterine growth retardation, preeclampsia and placenta ablation makes ASP a serious perinatologic problem. The primary form can evaluate into lupus-like disease or full-symptomatic lupus erythematosus, both usually preceded by acute form of APS. In pregnant women this situation may present considerable diagnostic problems. The aim of this work was to present a patient with acute primary antiphospholipid syndrome during pregnancy and puerperium, which subsequently was diagnosed as systemic lupus erythematosus flare. Such progression is rare and, despite several previous reports, requires extensive explanations and research.
authors: Klinika Perinatologii i Chorób Kobiecych Uniwersytet Medyczny w Poznaniu, Polska.
authors: Anna
authors: A
authors: Lorenc
authors: Agnieszka
authors: A
authors: Seremak-Mrozikiewicz
authors: Krzysztof
authors: K
authors: Drews
authors: Paweł
authors: P
authors: Ratajczak
authors: Mariusz
authors: M
authors: Puszczewicz
mesh_terms: D000328:Adult; D016736:Antiphospholipid Syndrome / Q000150:complications* / Q000175:diagnosis* / Q000628:therapy; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000175:diagnosis* / Q000628:therapy; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis* / Q000628:therapy; D011256:Pregnancy Outcome; D012307:Risk Factors