title: Plastoquinones from Sargassum yezoense; chemical structures and effects on the activation of peroxisome proliferator-activated receptor gamma.
abstract: Four new plastoquinones, together with two known compounds, sargahydroquinoic acid and sargaquinoic acid, were isolated from the brown alga, Sargassum yezoense collected from the eastern coast of Korea. The structures of these compounds were elucidated based on spectroscopic analyses including NMR and MS. Their structures designated as meroterphenol A (1), B (2), C (3) and D (4) were characterized by a 6-methyl-1,4-benzohydroquinone moiety with an oxygenated diterpenoic acid chain. Meroterphenols A-D showed potent activation effects on peroxisome proliferator-activated receptor gamma (PPARγ).
authors: Natural Products Research Center, Korea Institute of Science and Technology (KIST), Gangneung 210–340, Korea.
authors: Min Cheol
authors: MC
authors: Kim
authors: Hak Cheol
authors: HC
authors: Kwon
authors: Su Nam
authors: SN
authors: Kim
authors: Hyung Seop
authors: HS
authors: Kim
authors: Byung Hun
authors: BH
authors: Um
mesh_terms: D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D008968:Molecular Conformation; D047495:PPAR gamma / Q000819:agonists / Q000235:genetics / Q000378:metabolism*; D010971:Plastoquinone / Q000737:chemistry* / Q000302:isolation & purification; D044647:Sargassum / Q000737:chemistry*
chemical_list: D047495:PPAR gamma; D010971:Plastoquinone