title: Transvaginal mesh surgery for pelvic organ prolapse--Prolift+M: a prospective clinical trial.
abstract: OBJECTIVE
  This study deals with assessment of safety, efficacy, and potential complications of Prolift+M system to correct uterovaginal prolapse.
  
  
  METHODS
  We analyzed a prospective cohort treated with the Gynecare PROLIFT+M mesh system between October 2008 and March 2010. A composite score that included subjective/objective cure and lack of complications was used to assess treatment success.
  
  
  RESULTS
  One hundred sixty-seven women (age 65.1 ± 11.2 years, BMI 29.2 ± 5.8 kg/m(2)) were treated for pelvic organ prolapse using the PROLIFT+M system. Seven anterior Prolift+M, 42 posterior Prolift+M, and 118 total Prolift+M mesh surgeries were performed in patients with stage II or greater degrees of prolapse. Mean operative time was 122.7 ± 43.9 min. Mean intraoperative blood loss was 119.4 ± 125.3 ml. Our composite success score was 72.5% (treatment failures per POP-Q stage 1.4%, perception of bulge 4.4%, erosions 3.6%, pain/dyspareunia 3.7%, incontinence 0.7%, de novo urge urinary incontinence 8.7%, voiding dysfunction 0.6%, recurrent urinary tract infection 2.2%, and anal incontinence 2.2%).
  
  
  CONCLUSIONS
  Prolift+M surgery is safe and effective with minimal postoperative morbidities.
authors: Division of Urogynecology, Oakwood Hospital and Medical Center, Dearborn, MI, USA. salil@augm.org
authors: Salil
authors: S
authors: Khandwala
authors: Chaandini
authors: C
authors: Jayachandran
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016063:Blood Loss, Surgical; D004414:Dyspareunia / Q000209:etiology; D005242:Fecal Incontinence / Q000209:etiology; D005260:Female; D006801:Humans; D008875:Middle Aged; D056887:Pelvic Organ Prolapse / Q000473:pathology / Q000601:surgery*; D011183:Postoperative Complications / Q000209:etiology*; D011475:Prosthesis Failure / Q000209:etiology; D012725:Sexual Behavior; D013526:Surgical Mesh / Q000009:adverse effects; D011795:Surveys and Questionnaires; D013997:Time Factors; D016896:Treatment Outcome; D053202:Urinary Incontinence, Urge / Q000209:etiology; D014552:Urinary Tract Infections / Q000209:etiology; D014621:Vagina / Q000473:pathology / Q000601:surgery