title: Effects of hydrogen peroxide-containing bleaching on cariogenic bacteria and plaque accumulation.
abstract: OBJECTIVE
  To evaluate the effects of a commercial bleaching agent containing 36% hydrogen peroxide on the clinical plaque index and Streptococcus mutans and Lactobacilli counts in dental plaque and saliva in vivo.
  
  
  METHODS
  Twenty volunteers were recruited in the present study. Evaluation of plaque index and bacteria counts in plaque and saliva was performed before bleaching the teeth, and 3 days, 2 weeks and 4 weeks post-treatment.
  
  
  RESULTS
  Quigley-Hein Plaque Index and Modified Navy Plaque Index were significantly lower on day three after bleaching compared to that before bleaching and the other time points after bleaching. The total number of bacteria in the plaque on day three after bleaching was also less than that before bleaching and the other time points after bleaching. The Streptococcus mutans counts in the plaque and saliva four weeks after bleaching were decreased significantly compared to that before bleaching.
  
  
  CONCLUSIONS
  Hydrogen peroxide bleaching can decrease plaque accumulation and cariogenic bacteria for a short period of time.
authors: General Dentistry, Peking University School and Hospital of Stomatology, Beijing, PR China.
authors: Chun Yan
authors: CY
authors: Zheng
authors: Jie
authors: J
authors: Pan
authors: Lin
authors: L
authors: Wang
authors: Cheng Fei
authors: CF
authors: Zhang
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D015169:Colony Count, Microbial; D003773:Dental Plaque / Q000382:microbiology / Q000517:prevention & control*; D003774:Dental Plaque Index; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D006861:Hydrogen Peroxide / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D007778:Lactobacillus / Q000187:drug effects; D008297:Male; D012463:Saliva / Q000382:microbiology; D018709:Statistics, Nonparametric; D013295:Streptococcus mutans / Q000187:drug effects*; D014073:Tooth Bleaching; D058205:Tooth Bleaching Agents / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D055815:Young Adult
chemical_list: D058205:Tooth Bleaching Agents; D006861:Hydrogen Peroxide