title: Serologic evidence of arboviral infections among humans in Kenya.
abstract: Outbreaks of arthropod-borne viral infections occur periodically across Kenya. However, limited surveillance takes place during interepidemic periods. Using serum samples obtained from asymptomatic persons across Kenya in 2000-2004, we assessed (by indirect immunofluorescent assay) prevalence of IgG against yellow fever virus (YFV), West Nile virus (WNV), tick-borne encephalitis virus (TBEV), dengue virus serotypes 1-4 (DENV1-4), and chikungunya virus (CHIKV). Older persons on the Indian Ocean coast were more likely to be seropositive than children inland: YFV = 42% versus 6%, WNV = 29% versus 6%, TBEV = 16% versus 6%, DENV-1 = 63% versus 9%, DENV-2 = 67% versus 7%, DENV-3 = 55% versus 6%, DENV-4 = 44% versus 8%, and CHIKV = 37% versus 20%. Among inland samples, children in lowlands were more likely to be seropositive for CHIKV (42% versus 0%) than children in highlands. In Kenya, transmission of arboviral infection continues between known epidemics and remains common across the country.
authors: Center for Global Health and Diseases, Case Western Reserve University, Cleveland, Ohio 44106, USA. chikungunya.ljs@gmail.com
authors: Laura J
authors: LJ
authors: Sutherland
authors: Ayla A
authors: AA
authors: Cash
authors: Yan-Jang Scott
authors: YJ
authors: Huang
authors: Rosemary C
authors: RC
authors: Sang
authors: Indu
authors: I
authors: Malhotra
authors: Ann M
authors: AM
authors: Moormann
authors: Christopher L
authors: CL
authors: King
authors: Scott C
authors: SC
authors: Weaver
authors: Charles H
authors: CH
authors: King
authors: A Desiree
authors: AD
authors: LaBeaud
mesh_terms: D000818:Animals; D001102:Arbovirus Infections / Q000097:blood / Q000175:diagnosis* / Q000453:epidemiology; D001179:Arthropod Vectors; D004196:Disease Outbreaks; D019084:Fluorescent Antibody Technique, Indirect; D006801:Humans; D007630:Kenya / Q000453:epidemiology; D016036:Seroepidemiologic Studies