title: New prenylated C₆-C₃ compounds from the twigs of Illicium anisatum.
abstract: Two new prenylated C₆-C₃ compounds, cycloillicinone (1) and 4-allyl-2-methoxy-6-(2-methylbut-3-en-2-yl)phenol (2), were isolated from the twigs of Illicium anisatum, and their structures were determined by 2D-NMR methods. Cycloillicinone (1) is a unique prenylated C₆-C₃ that is appended with an additional geranyl unit. Compound 2 was found to show moderate neurite-outgrowth promoting activity in primary cultured rat cortical neurons at a concentration of 10 µM.
authors: Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Tokushima, Japan.
authors: Miwa
authors: M
authors: Kubo
authors: Naoki
authors: N
authors: Shima
authors: Kenichi
authors: K
authors: Harada
authors: Hideaki
authors: H
authors: Hioki
authors: Yoshiyasu
authors: Y
authors: Fukuyama
mesh_terms: D000818:Animals; D002478:Cells, Cultured; D029523:Illicium / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D009474:Neurons / Q000166:cytology / Q000187:drug effects; D010636:Phenols / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D051381:Rats; D013729:Terpenes / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology
chemical_list: C561822:4-allyl-2-methoxy-6-(2-methylbut-3-en-2-yl)phenol; D010636:Phenols; D013729:Terpenes; C561821:cycloillicinone