title: Functional and anatomic results after creation of a neovagina according to Wharton-Sheares-George in patients with Mayer-Rokitansky-Küster-Hauser syndrome-long-term follow-up.
abstract: OBJECTIVE
  To evaluate the long-term outcomes and degree of satisfaction after neovaginoplasty according to Wharton-Sheares-George in women with Mayer-Rokitansky-Küster-Hauser syndrome.
  
  
  METHODS
  Open, monocentric follow-up study.
  
  
  METHODS
  University hospital and referral center for pediatric and adolescent gynecology.
  
  
  METHODS
  Ten patients with Mayer-Rokitansky-Küster-Hauser syndrome with neovaginas created according to Wharton-Sheares-George 3 to 77 months ago.
  
  
  METHODS
  Gynecologic follow-up examination, including vaginal swab, bacterial culture, Papanicolaou smear, hybrid capture test for human papillomavirus typing, biopsy, pelvic ultrasound, and 2 questionnaires concerning global quality of life and degree of sexual satisfaction.
  
  
  METHODS
  Satisfaction with sexual function, quality of life, length and width of neovagina, structure of vaginal epithelium, and type of bacterial colonization.
  
  
  RESULTS
  Functional long-term follow-up results showed a high subjective degree of general well-being and sexual satisfaction in affected women. A satisfactory neovaginal length (mean, 8.3 ± 1.06 cm; range, 7-10 cm) and width (mean, 3.3 ± 0.5 cm; range, 2.5-4 cm) was obtained. As revealed by smears and biopsy, the neovagina resembled a natural vagina with regard to type of bacterial colonization and structure of epithelium.
  
  
  CONCLUSIONS
  The goal of any method of creating a neovagina is to provide the patient the possibility to have satisfactory sexual intercourse and to enhance well-being and quality of life. These aims can be achieved by creating a neovagina according to Wharton-Sheares-George.
authors: Department of Obstetrics and Gynecology, Medical University of Vienna, Vienna, Austria.
authors: Katharina
authors: K
authors: Walch
authors: Eleen
authors: E
authors: Kowarik
authors: Katharina
authors: K
authors: Leithner
authors: Theresa
authors: T
authors: Schätz
authors: Daniela
authors: D
authors: Dörfler
authors: René
authors: R
authors: Wenzl
mesh_terms: D058489:46, XX Disorders of Sex Development / Q000503:physiopathology / Q000523:psychology / Q000601:surgery*; D000015:Abnormalities, Multiple / Q000503:physiopathology / Q000523:psychology / Q000601:surgery*; D000293:Adolescent; D000328:Adult; D001317:Austria; D001706:Biopsy; D003075:Coitus; D000013:Congenital Abnormalities; D005260:Female; D005500:Follow-Up Studies; D013509:Gynecologic Surgical Procedures; D006785:Hospitals, University; D006801:Humans; D007668:Kidney / Q000002:abnormalities; D010535:Laparoscopy; D009095:Mullerian Ducts / Q000002:abnormalities; D065006:Papanicolaou Test; D017060:Patient Satisfaction; D011788:Quality of Life; D012725:Sexual Behavior; D019170:Somites / Q000002:abnormalities; D013131:Spine / Q000002:abnormalities; D019738:Surgically-Created Structures / Q000382:microbiology; D011795:Surveys and Questionnaires; D013997:Time Factors; D016896:Treatment Outcome; D014599:Uterus / Q000002:abnormalities / Q000503:physiopathology / Q000601:surgery; D014621:Vagina / Q000002:abnormalities / Q000503:physiopathology / Q000601:surgery; D014626:Vaginal Smears; D055815:Young Adult