title: Diagnostic performance of 320-slice multidetector computed tomography coronary angiography in patients after coronary artery bypass grafting.
abstract: OBJECTIVE
  To evaluate the diagnostic performance of 320-slice computed tomography coronary angiography (CTA) in the evaluation of patients with prior coronary artery bypass grafting (CABG). Invasive coronary angiography (ICA) served as the standard of reference, using a quantitative approach.
  
  
  METHODS
  CTA studies were performed using CT equipment with 320 detector-rows, each 0.5 mm wide, and a gantry rotation time of 0.35 s. All grafts, recipient and nongrafted vessels were deemed interpretable or uninterpretable. The presence of significant (≥50%) stenosis and occlusion were determined on vessel and patient basis. Results were compared to ICA using quantitative coronary angiography.
  
  
  RESULTS
  A total of 40 patients (28 men, 76 ± 15 years), with 89 grafts, were included in the study. On a graft analysis, the sensitivity, specificity, positive and negative predictive values in the evaluation of significant stenosis were 96%, 92%, 83% and 98% respectively. The diagnostic accuracy for the assessment of recipient and nongrafted vessels was 89% and 80%, respectively. The diagnostic accuracy for the assessment of graft, recipient and nongrafted vessel occlusion was 96%, 92% and 100%, respectively.
  
  
  CONCLUSIONS
  320-slice CTA allows accurate non-invasive assessment of significant graft, recipient vessel and nongrafted vessel stenosis in patients with prior CABG.
authors: Department of Cardiology, Leiden University Medical Center, Albinusdreef 2 Postal zone: C5-P, P.O. Box 9600, 2300 RC Leiden, The Netherlands. f.r.de_graaf@lumc.nl
authors: Fleur R
authors: FR
authors: de Graaf
authors: Joëlla E
authors: JE
authors: van Velzen
authors: Agnieszka J
authors: AJ
authors: Witkowska
authors: Joanne D
authors: JD
authors: Schuijf
authors: Noortje
authors: N
authors: van der Bijl
authors: Lucia J
authors: LJ
authors: Kroft
authors: Albert
authors: A
authors: de Roos
authors: Johan H C
authors: JH
authors: Reiber
authors: Jeroen J
authors: JJ
authors: Bax
authors: Greetje J
authors: GJ
authors: de Grooth
authors: J Wouter
authors: JW
authors: Jukema
authors: Ernst E
authors: EE
authors: van der Wall
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D017023:Coronary Angiography / Q000379:methods*; D001026:Coronary Artery Bypass / Q000379:methods*; D003331:Coronary Vessels / Q000473:pathology*; D003952:Diagnostic Imaging / Q000379:methods; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D061330:Multidetector Computed Tomography / Q000379:methods*; D011237:Predictive Value of Tests; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity