title: Relation between cooperative molecular motors and active Brownian particles.
abstract: Active Brownian particles (ABPs), obeying a nonlinear Langevin equation with speed-dependent drift and noise amplitude, are well-known models used to describe self-propelled motion in biology. In this paper we study a model describing the stochastic dynamics of a group of coupled molecular motors (CMMs). Using two independent numerical methods, one based on the stationary velocity distribution of the motors and the other one on the local increments (also known as the Kramers-Moyal coefficients) of the velocity, we establish a connection between the CMM and the ABP models. The parameters extracted for the ABP via the two methods show good agreement for both symmetric and asymmetric cases and are independent of N, the number of motors, provided that N is not too small. This indicates that one can indeed describe the CMM problem with a simpler ABP model. However, the power spectrum of velocity fluctuations in the CMM model reveals a peak at a finite frequency, a peak which is absent in the velocity spectrum of the ABP model. This implies richer dynamic features of the CMM model which cannot be captured by an ABP model.
authors: Max-Planck-Institut für Physik komplexer Systeme, Dresden, Germany.
authors: Clément
authors: C
authors: Touya
authors: Tilo
authors: T
authors: Schwalger
authors: Benjamin
authors: B
authors: Lindner
mesh_terms: D008954:Models, Biological; D020409:Molecular Motor Proteins / Q000378:metabolism*; D009068:Movement; D013816:Thermodynamics
chemical_list: D020409:Molecular Motor Proteins