title: Antibody-functionalized SERS tags with improved sensitivity.
abstract: Protein detection at the femtomolar level can be achieved by using metallic nanoparticle assemblies that function as surface enhanced Raman spectroscopy reporters and that contain suitable surface-bound recognition elements. Proper control of the interaction between nanoparticles within the assemblies is critical for achieving this performance.
authors: Instituto de Ciencia y Tecnología de Polímeros (ICTP), Consejo Superior de Investigaciones Científicas (CSIC), Juan de la Cierva 3, 28006 Madrid, Spain. nekane@ictp.csic.es
authors: Nekane
authors: N
authors: Guarrotxena
authors: Guillermo C
authors: GC
authors: Bazan
mesh_terms: D000906:Antibodies / Q000276:immunology*; D006046:Gold / Q000737:chemistry; D006801:Humans; D053768:Metal Nanoparticles / Q000737:chemistry; D011092:Polyethylene Glycols / Q000737:chemistry; D013059:Spectrum Analysis, Raman; D013917:Thrombin / Q000032:analysis / Q000276:immunology
chemical_list: D000906:Antibodies; D011092:Polyethylene Glycols; D006046:Gold; D013917:Thrombin