title: Antihistamine therapy in allergic rhinitis.
abstract: Antihistamines have long been a mainstay in the therapy for allergic rhinitis. Many different oral antihistamines are available for use, and they are classified as first generation or second generation based on their pharmacologic properties and side-effect profiles. The recent introduction of intranasal antihistamines has further expanded the role of antihistamines in the treatment of allergic rhinitis. Certain patient populations, such as children and pregnant or lactating women, require special consideration regarding antihistamine choice and dosing as part of rhinitis therapy.
authors: Division of Allergy, Asthma, and Immunology, National Jewish Health, 1400 Jackson Street, Room K624, Denver, CO 80206, USA.
authors: Flavia C L
authors: FC
authors: Hoyte
authors: Rohit K
authors: RK
authors: Katial
mesh_terms: D000281:Administration, Intranasal; D000284:Administration, Oral; D000305:Adrenal Cortex Hormones / Q000008:administration & dosage / Q000627:therapeutic use; D002648:Child; D005260:Female; D006632:Histamine / Q000266:history / Q000378:metabolism; D006633:Histamine Antagonists / Q000008:administration & dosage / Q000737:chemistry / Q000266:history / Q000627:therapeutic use*; D049672:History, 19th Century; D049673:History, 20th Century; D006801:Humans; D008297:Male; D011247:Pregnancy; D011968:Receptors, Histamine / Q000378:metabolism; D012221:Rhinitis, Allergic, Perennial / Q000188:drug therapy*; D006255:Rhinitis, Allergic, Seasonal / Q000188:drug therapy*; D016896:Treatment Outcome
chemical_list: D000305:Adrenal Cortex Hormones; D006633:Histamine Antagonists; D011968:Receptors, Histamine; D006632:Histamine