title: In vitro antimicrobial activity of Romanian medicinal plants hydroalcoholic extracts on planktonic and adhered cells.
abstract: The aim of this study was to assess the antibacterial and antifungal potential of some Romanian medicinal plants, arnica--Arnica montana, wormwood--Artemisia absinthium and nettle--Urtica dioica. In order to perform this antimicrobial screening, we obtained the vegetal extracts and we tested them on a series of Gram-positive and Gram-negative bacteria, and also against two fungal strains. The vegetal extracts showed antimicrobial activity preferentially directed against the planktonic fungal and bacterial growth, while the effect against biofilm formation and development was demonstrated only against S. aureus and C. albicans. Our in vitro assays indicate that the studied plant extracts are a significant source of natural alternatives to antimicrobial therapy, thus avoiding antibiotic therapy, the use of which has become excessive in recent years.
authors: National Institute R&D for Biological Sciences, Department of Cellular and Molecular Biology, 296 Splaiul Independentei, 060031, Bucharest, Romania. annastanciuc@yahoo.fr
authors: A M
authors: AM
authors: Stanciuc
authors: A
authors: A
authors: Gaspar
authors: L
authors: L
authors: Moldovan
authors: C
authors: C
authors: Saviuc
authors: M
authors: M
authors: Popa
authors: L
authors: L
authors: Măruţescu
mesh_terms: D000890:Anti-Infective Agents / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects; D018441:Biofilms / Q000187:drug effects; D002176:Candida albicans / Q000187:drug effects; D010933:Plankton / Q000187:drug effects*; D010936:Plant Extracts / Q000494:pharmacology*; D010946:Plants, Medicinal; D012383:Romania
chemical_list: D000890:Anti-Infective Agents; D010936:Plant Extracts