title: Changes in risk perceptions in relation to self-reported colorectal cancer screening among first-degree relatives of colorectal cancer cases enrolled in a randomized trial.
abstract: OBJECTIVE
  This secondary data analysis was conducted to evaluate the applicability of the Risk Reappraisal Hypothesis, which has been proposed to explain the influence of performing a health behavior on perceived risk. Data were collected in the context of a randomized trial, which found that an individually tailored, multicomponent intervention was successful in increasing colorectal cancer (CRC) screening among first-degree relatives of CRC cases.
  
  
  METHODS
  The ethnically diverse study sample (N = 841; 29% Latino, 21% African American, 20% Asian) consisted of adult siblings and children (40-80 years) of CRC cases, identified through the California Cancer Registry. Data were collected at baseline and at 6- and 12-month follow-up. Changes in self-reported risk perception (perceived likelihood of developing CRC) were examined over the study period in relation to study condition and screening status.
  
  
  RESULTS
  Greater increases in perceived risk were observed among intervention versus control-group participants over the study period, but increases were limited to intervention participants who had not been screened. We also examined trajectories of perceived risk in relation to timing of screening receipt (e.g., before 6 months, 6-12 months, never). Continued upward shifts in risk were observed during the study period among intervention participants not screened during the study. In contrast, participants screened by 6 months displayed a reduction or leveling off in perceived risk between 6- and 12-month follow-up.
  
  
  CONCLUSIONS
  Results provide support for the applicability of the Risk Reappraisal Hypothesis within a high-risk sample enrolled in a CRC screening promotion trial. Future research is needed to explore the impact of short-term risk reductions on future CRC screening behavior.
authors: Division of Cancer Prevention & Control Research, School of Public Health & Jonsson Comprehensive Cancer Center, University of California, Los Angeles, CA 90095-6900, USA. bglenn@ucla.edu
authors: Beth A
authors: BA
authors: Glenn
authors: Alison K
authors: AK
authors: Herrmann
authors: Catherine M
authors: CM
authors: Crespi
authors: Cynthia M
authors: CM
authors: Mojica
authors: L Cindy
authors: LC
authors: Chang
authors: Annette E
authors: AE
authors: Maxwell
authors: Roshan
authors: R
authors: Bastani
mesh_terms: D000328:Adult; D032721:Adult Children / Q000523:psychology; D000368:Aged; D000369:Aged, 80 and over; D002140:California; D015179:Colorectal Neoplasms / Q000175:diagnosis* / Q000523:psychology*; D055088:Early Detection of Cancer / Q000523:psychology*; D005260:Female; D015438:Health Behavior; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D008297:Male; D008875:Middle Aged; D012042:Registries; D018570:Risk Assessment; D012647:Self-Assessment; D035781:Siblings / Q000523:psychology