title: Clinical features of ocular toxoplasmosis in Korean patients.
abstract: We report here the records of 10 consecutive Korean patients (10 eyes) with ocular toxoplasmosis which showed the typical clinical manifestations with seropositivity for Toxoplasma gondii specific IgG antibodies by micro-ELISA between 2006 and 2010. Nine patients were males and 1 was female; their age was 50.5 ± 13.8 years. The most common accompanying signs were vitritis (100%), anterior uveitis (70%), and scattered white deposit (80%). Pre-existing retinochoroidal scar was found in 1 (10%) patient. All patients received antiparasitic chemotherapy and systemic corticosteroid treatment, which resolved the presenting attack and recovered the visual acuity better than initial one in 9 patients and worse in 1. Optic atrophy, cataract, and retinal neovascularization were observed during the follow-up period and recurrence was detected in 3 eyes (30%) 6 to 20 months after the initial attack. In Korea, although rarely detected and reported, ocular toxoplasmosis needs more attention in clinical field of retinal diseases.
authors: Department of Ophthalmology and Visual Science, College of Medicine, The Catholic University of Korea, Seoul 137-701, Korea.
authors: Young-Hoon
authors: YH
authors: Park
authors: Jae-Hyung
authors: JH
authors: Han
authors: Ho-Woo
authors: HW
authors: Nam
mesh_terms: D000305:Adrenal Cortex Hormones / Q000008:administration & dosage; D000328:Adult; D017677:Age Distribution; D000368:Aged; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage; D000913:Antibodies, Protozoan / Q000097:blood*; D000981:Antiprotozoal Agents / Q000008:administration & dosage; D002386:Cataract / Q000473:pathology; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D007723:Korea; D008297:Male; D008875:Middle Aged; D009896:Optic Atrophy / Q000473:pathology; D015861:Retinal Neovascularization / Q000473:pathology; D017678:Sex Distribution; D014122:Toxoplasma / Q000276:immunology / Q000302:isolation & purification*; D014126:Toxoplasmosis, Ocular / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology*; D014606:Uveitis, Anterior / Q000150:complications / Q000188:drug therapy / Q000469:parasitology / Q000473:pathology
chemical_list: D000305:Adrenal Cortex Hormones; D000893:Anti-Inflammatory Agents; D000913:Antibodies, Protozoan; D000981:Antiprotozoal Agents; D007074:Immunoglobulin G