title: Aplasia cutis congenita: impact of early treatment on calvarial osteogenesis.
abstract: We describe an infant with severe aplasia cutis congenita of the scalp that was characterised by a full-thickness calvarial bone defect combined with the absence of dura mater complicated by sagittal sinus haemorrhage. The defect was successfully managed by closure with a local temporal flap combined with a periosteum patch to allow closure of the dura mater. Previously, conservative treatments failed to remedy unexpected, massive bleeding, which could potentially threaten a patient's life. We highlight the osteogenic potential of surgically manipulated dura mater in this patient who was managed early with a surgical approach.
authors: Hospital de Crânio e Face SOBRAPAR, Institute of Plastic and Craniofacial Surgery, Campinas-SP, Brazil. cassioeduardo@sobrapar.org.br
authors: Cassio E
authors: CE
authors: Raposo-Amaral
authors: Cesar A
authors: CA
authors: Raposo-Amaral
mesh_terms: D004388:Dura Mater / Q000002:abnormalities; D004476:Ectodermal Dysplasia / Q000601:surgery*; D006470:Hemorrhage / Q000209:etiology / Q000601:surgery; D006801:Humans; D007223:Infant; D008297:Male; D010012:Osteogenesis; D010521:Periosteum / Q000637:transplantation*; D012886:Skull / Q000002:abnormalities / Q000254:growth & development* / Q000601:surgery*; D054063:Superior Sagittal Sinus; D013524:Surgical Flaps