title: New insights in plant immunity signaling activation.
abstract: Plant disease resistance can be triggered by specific recognition of microbial effectors by plant nucleotide binding-leucine rich repeat (NB-LRR) receptors. Over the last few years, many efforts have greatly improved the understanding of effector and NB-LRR function, but have left a lot of questions as to how effector perception activates NB-LRR induction of defense signaling. This review describes exciting new findings showing similarities and differences in function of diverse plant NB-LRR proteins in terms of pathogen recognition and where and how resistance proteins are activated. Localization studies have shown that some NB-LRRs can activate signaling from the cytosol while others act in the nucleus. Also, the structural determination of two NB-LRR signaling domains demonstrated that receptor oligomerization is fundamental for the activation of resistance signaling.
authors: CSIRO Plant Industry, Canberra, Australian Capital Territory 2601, Australia.
authors: Maud
authors: M
authors: Bernoux
authors: Jeffrey G
authors: JG
authors: Ellis
authors: Peter N
authors: PN
authors: Dodds
mesh_terms: D003674:Defense Mechanisms; D060467:Disease Resistance; D010935:Plant Diseases / Q000276:immunology*; D057865:Plant Immunity / Q000502:physiology*; D010940:Plant Proteins / Q000276:immunology*; D015398:Signal Transduction
chemical_list: D010940:Plant Proteins