title: Arterial vascularisation of the anterior perforated substance.
abstract: BACKGROUND
  The arteries of the anterior perforated substance (APS) are important due to their role in supplying blood to important internal structures such as the internal capsule, putamen and caudate nucleus. The purpose of this study was to investigate in detail the arteries of the APS.
  
  
  METHODS
  The arteries of the APS were investigated in 60 cerebral hemispheres from 30 adult cadaveric brains. The internal carotid arteries were cannulated and perfused with coloured latex. The branches of the middle cerebral artery (MCA) penetrating the APS were investigated. These arteries, known as the lateral lenticulostriate arteries and originating from the M1 segment, early temporal and early frontal branches of the MCA, were recorded.
  
  
  RESULTS
  The branches of the anterior choroidal artery, which reached the APS, were seen in all specimens. We found one to three branches that arose from the A2 segment of the anterior cerebral artery (ACA) to the APS in all hemispheres, and one to three branches that originated from the A1 segment of the ACA in 48 hemispheres. In addition, two accessory MCAs that originated from the A2 segment of the ACA were recorded as variations, and perforating branches to the APS were observed.
  
  
  CONCLUSIONS
  Serious complications like motor deficits can occur as a result of injury to the arteries of the APS. Hence, neurosurgeons performing operations such as aneurysm or insular tumour surgeries must be aware of the importance of preserving these arteries.
authors: Department of Anatomy, Ankara University School of Medicine, Morfoloji Binasi, Sihhiye, Ankara 06100, Turkey.
authors: T
authors: T
authors: Sen
authors: A F
authors: AF
authors: Esmer
authors: H I
authors: HI
authors: Acar
authors: S T
authors: ST
authors: Karahan
authors: E
authors: E
authors: Tuccar
mesh_terms: D001158:Arteries / Q000033:anatomy & histology / Q000473:pathology*; D001921:Brain / Q000033:anatomy & histology* / Q000098:blood supply*; D002102:Cadaver; D002421:Caudate Nucleus / Q000098:blood supply*; D002560:Cerebrovascular Circulation; D006801:Humans; D020772:Internal Capsule / Q000098:blood supply*; D007840:Latex; D011699:Putamen / Q000098:blood supply*; D013997:Time Factors
chemical_list: D007840:Latex