title: In vitro evaluation of hexagonal polymeric micelles in macrophage phagocytosis.
abstract: This paper develops a non-spherical polymeric micelle using an amphiphilic block copolymer and a porphyrin crystalline structure. The nanoscale polymer micelles were characterized by transmission electron microscopy (TEM) and atomic force microscopy (AFM), revealing particle sizes of approximately 150 nm with a particular shape in the hexagonal lattice. The shape shows the selective uptake efficacy for the HeLa and macrophage cells, and inhibits phagocytosis against the macrophage.
authors: Graduate Institute of Applied Science and Technology, National Taiwan University of Science and Technology, Taipei, Taiwan, ROC. h.c.tsai@mail.ntust.edu.tw
authors: Hsieh-Chih
authors: HC
authors: Tsai
authors: Che-Hau
authors: CH
authors: Chang
authors: Yie-Chan
authors: YC
authors: Chiu
authors: Shuian-Yin
authors: SY
authors: Lin
authors: Che-Ping
authors: CP
authors: Lin
authors: Ging-Ho
authors: GH
authors: Hsiue
mesh_terms: D004337:Drug Carriers / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D016503:Drug Delivery Systems / Q000295:instrumentation*; D006367:HeLa Cells; D006801:Humans; D008264:Macrophages / Q000187:drug effects / Q000502:physiology*; D008823:Micelles; D010316:Particle Size; D010587:Phagocytosis / Q000187:drug effects; D011108:Polymers / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology
chemical_list: D004337:Drug Carriers; D008823:Micelles; D011108:Polymers