title: [From the physiology of pain to an antihyperalgesic nutritional approach].
abstract: Pain is brought into play by a system which detects and transmits messages signaling pain. Opioids negatively modulate nociception, but paradoxically also contribute to hyperalgesia. A nutritional approach with low polyamine contents helps to reduce this phenomenon without the harmful side effects of antihyperalgesic drugs.
authors: Département d'anesthésie-réanimation-douleur, Institut Curie, Paris. alicedesmouliere@hotmail.fr
authors: Alice
authors: A
authors: de la Brière
mesh_terms: D000701:Analgesics, Opioid / Q000008:administration & dosage / Q000009:adverse effects; D015317:Biogenic Polyamines / Q000008:administration & dosage*; D001921:Brain / Q000503:physiopathology; D002908:Chronic Disease; D002149:Energy Intake; D005602:France; D006801:Humans; D006930:Hyperalgesia / Q000178:diet therapy / Q000451:nursing* / Q000503:physiopathology; D009619:Nociceptors / Q000502:physiology; D010146:Pain / Q000178:diet therapy* / Q000451:nursing* / Q000503:physiopathology; D016194:Receptors, N-Methyl-D-Aspartate / Q000502:physiology; D009435:Synaptic Transmission / Q000502:physiology
chemical_list: D000701:Analgesics, Opioid; D015317:Biogenic Polyamines; D016194:Receptors, N-Methyl-D-Aspartate