title: Roles of multidrug efflux pumps on the biofilm formation of Escherichia coli K-12.
abstract: We genetically analyzed the roles of multidrug efflux pumps on the biofilm formation of Escherichia coli K-12 BW25113. We used 22 mutants missing various genes related to the multidrug efflux pumps and found that the biofilm formation of emrD, emrE, emrK, acrD, acre and mdtE-deleted mutants was extremely decreased. These results indicate that some multidrug efflux pumps significantly contribute to the biofilm formation of E. coli.
authors: Department of Food Bioscience and Biotechnology, College of Bioresource Science, Nihon University, Kameino, Fujisawa, Japan. furukawa@brs.nihon-u.ac.jp
authors: Kayo
authors: K
authors: Matsumura
authors: Soichi
authors: S
authors: Furukawa
authors: Hirokazu
authors: H
authors: Ogihara
authors: Yasushi
authors: Y
authors: Morinaga
mesh_terms: D018441:Biofilms / Q000254:growth & development*; D024901:Drug Resistance, Multiple, Bacterial; D048168:Escherichia coli K12 / Q000235:genetics* / Q000254:growth & development; D017353:Gene Deletion; D005798:Genes, Bacterial / Q000235:genetics / Q000502:physiology*; D019450:Genes, MDR / Q000502:physiology*; D057927:Hydrophobic and Hydrophilic Interactions; D011137:Polystyrenes / Q000737:chemistry; D013499:Surface Properties
chemical_list: D011137:Polystyrenes