title: Bonobos fall within the genomic variation of chimpanzees.
abstract: To gain insight into the patterns of genetic variation and evolutionary relationships within and between bonobos and chimpanzees, we sequenced 150,000 base pairs of nuclear DNA divided among 15 autosomal regions as well as the complete mitochondrial genomes from 20 bonobos and 58 chimpanzees. Except for western chimpanzees, we found poor genetic separation of chimpanzees based on sample locality. In contrast, bonobos consistently cluster together but fall as a group within the variation of chimpanzees for many of the regions. Thus, while chimpanzees retain genomic variation that predates bonobo-chimpanzee speciation, extensive lineage sorting has occurred within bonobos such that much of their genome traces its ancestry back to a single common ancestor that postdates their origin as a group separate from chimpanzees.
authors: Max Plank Institute for Evolutionary Anthropology, Leipzig, Germany. afischer@icipe.org
authors: Anne
authors: A
authors: Fischer
authors: Kay
authors: K
authors: Prüfer
authors: Jeffrey M
authors: JM
authors: Good
authors: Michel
authors: M
authors: Halbwax
authors: Victor
authors: V
authors: Wiebe
authors: Claudine
authors: C
authors: André
authors: Rebeca
authors: R
authors: Atencia
authors: Lawrence
authors: L
authors: Mugisha
authors: Susan E
authors: SE
authors: Ptak
authors: Svante
authors: S
authors: Pääbo
mesh_terms: D000818:Animals; D004272:DNA, Mitochondrial / Q000235:genetics; D019143:Evolution, Molecular; D014644:Genetic Variation; D016678:Genome / Q000235:genetics*; D006801:Humans; D008297:Male; D019974:Pan paniscus / Q000235:genetics*; D002679:Pan troglodytes / Q000235:genetics*; D010802:Phylogeny; D017422:Sequence Analysis, DNA
chemical_list: D004272:DNA, Mitochondrial