title: Effects of the artificial sweetener sucralose on Daphnia magna and Americamysis bahia survival, growth and reproduction.
abstract: The artificial sweetener sucralose has been detected in municipal wastewater effluent and surface waters at concentrations ranging from ng/L to low μg/L. Few chronic ecotoxicological data are available in the peer reviewed literature with respect to sucralose. To address this data gap, 21 d Daphnia magna and 28 d Americamysis bahia (mysid shrimp) studies were conducted to assess the effects of sucralose on the survival, growth and reproduction of these organisms. Concentrations ⩽1800mg/L resulted in no statistically significant reduction in D. magna survival or reproduction. Survival, growth and reproduction of mysid shrimp were unaffected by ⩽93mg/L sucralose. The no observable effect concentration (NOEC) and lowest observable effect concentration (LOEC) for the D. magna study were 1800 and >1800mg/L, respectively. The NOEC and LOEC for the mysid study were 93 and >93mg/L, respectively. Collectively, these data suggest that the concentrations of sucralose detected in the environment are well below those required to elicit chronic effects in freshwater or marine invertebrates.
authors: Department of Biological Sciences, University of North Texas, Denton, TX 76203, USA. dbhuggett@unt.edu
authors: D B
authors: DB
authors: Huggett
authors: K I
authors: KI
authors: Stoddard
mesh_terms: D000818:Animals; D003445:Crustacea / Q000187:drug effects* / Q000254:growth & development; D003621:Daphnia / Q000187:drug effects* / Q000254:growth & development; D005260:Female; D019055:No-Observed-Adverse-Effect Level; D012098:Reproduction / Q000187:drug effects; D013395:Sucrose / Q000031:analogs & derivatives* / Q000633:toxicity; D013549:Sweetening Agents / Q000633:toxicity*; D018675:Toxicity Tests; D014874:Water Pollutants, Chemical / Q000633:toxicity*
chemical_list: D013549:Sweetening Agents; D014874:Water Pollutants, Chemical; D013395:Sucrose; C026285:trichlorosucrose