title: Medicinal Flowers. XXXII. Structures of oleanane-type triterpene saponins, perennisosides VIII, IX, X, XI, and XII, from the flowers of Bellis perennis.
abstract: Five new triterpene saponins perennisosides VIII (1), IX (2), X (3), XI (4), and XII (5) were isolated from the MeOH-eluated fraction of the methanolic extract from the flowers of Bellis perennis. The MeOH-eluted fraction of the methanolic extract from the flowers of B. perennis was found to inhibit gastric emptying in olive oil-loaded mice at a dose of 200 mg/kg, per os (p.o.). The stereostructures of 1-5 were elucidated on the basis of chemical and spectroscopic evidence.
authors: Pharmaceutical Research and Technology Institute, Kinki University.
authors: Toshio
authors: T
authors: Morikawa
authors: Xuezheng
authors: X
authors: Li
authors: Eriko
authors: E
authors: Nishida
authors: Seikou
authors: S
authors: Nakamura
authors: Kiyofumi
authors: K
authors: Ninomiya
authors: Hisashi
authors: H
authors: Matsuda
authors: Makoto
authors: M
authors: Hamao
authors: Osamu
authors: O
authors: Muraoka
authors: Takao
authors: T
authors: Hayakawa
authors: Masayuki
authors: M
authors: Yoshikawa
mesh_terms: D000818:Animals; D019659:Asteraceae / Q000737:chemistry*; D035264:Flowers / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D051379:Mice; D008968:Molecular Conformation; D009828:Oleanolic Acid / Q000737:chemistry*; D000069463:Olive Oil; D010938:Plant Oils / Q000633:toxicity; D010946:Plants, Medicinal / Q000737:chemistry; D012503:Saponins / Q000737:chemistry* / Q000302:isolation & purification / Q000627:therapeutic use; D013237:Stereoisomerism; D013272:Stomach Diseases / Q000139:chemically induced / Q000188:drug therapy
chemical_list: D000069463:Olive Oil; D010938:Plant Oils; D012503:Saponins; D009828:Oleanolic Acid