title: Relationship between three-year survival and functional outcome at discharge from acute-care hospitals in each subtype of first-ever ischemic stroke patients.
abstract: BACKGROUND
  We studied the relationship between survival prognosis and the functional outcome at discharge from acute-care hospitals in each subtype of ischemic stroke patients.
  
  
  METHODS
  A total of 853 consecutive patients with first-ever ischemic stroke, recruited from December 1999 to November 2002, were followed for 725.8 ± 430.0 days. Functional outcome was scored using the modified Rankin scale (mRS). Survival analysis was performed using Kaplan-Meier curves, log rank test, and Cox regression model.
  
  
  RESULTS
  The respective mortality of the groups with mRS scores of 0-2, 3, 4, and 5 were 13.1%, 25.0%, 47.2% (p<0.05), and 74.0% (p<0.05) in cardioembolic infarction (CEI) patients; 11.3%, 6.9%, 5.6%, and 46.7% (p<0.05) in atherothrombotic infarction (ATI) patients; 8.5%, 5.6%, 11.1%, and 0% (no patient) in lacunar infarction (LACI) patients; and 2.6%, 3.0%, 23.3% (p<0.05), and 28.9% (p<0.05) in infarction of unknown cause (IUC) patients. Multi-variate analysis showed that the mRS score was a significant predictive factor for death in CEI patients, and tended to be a predictive factor for death in ATI patients, or IUC patients.
  
  
  CONCLUSIONS
  Functional outcome at discharge from acute-care hospitals may predict the survival prognosis of each subtype of ischemic stroke.
authors: Division of Neurology, Department of Brain and Neurosciences, Faculty of Medicine, Tottori University, Japan. sutou@med.tottori-u.ac.jp
authors: Yutaka
authors: Y
authors: Suto
authors: Hisanori
authors: H
authors: Kowa
authors: Hiroyuki
authors: H
authors: Nakayasu
authors: Etsuko
authors: E
authors: Awaki
authors: Jun
authors: J
authors: Saito
authors: Yoshito
authors: Y
authors: Irizawa
authors: Kenji
authors: K
authors: Nakashima
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002545:Brain Ischemia / Q000175:diagnosis* / Q000401:mortality* / Q000503:physiopathology; D005260:Female; D006761:Hospitals / Q000639:trends*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010351:Patient Discharge / Q000639:trends*; D011446:Prospective Studies; D020127:Recovery of Function / Q000502:physiology; D020521:Stroke / Q000401:mortality* / Q000503:physiopathology; D015996:Survival Rate / Q000639:trends; D013997:Time Factors; D016896:Treatment Outcome