title: Synthesis of epoxybenzo[d]isothiazole 1,1-dioxides via a reductive-Heck, metathesis-sequestration protocol.
abstract: An atom-economical purification protocol, using solution phase processing via ring-opening metathesis polymerization (ROMP) has been developed for the synthesis of tricyclic sultams. This chromatography-free method allows for convenient isolation of reductive-Heck products and reclamation of excess starting material via sequestration involving metathesis catalysts and a catalyst-armed Si-surface.
authors: Department of Chemistry, University of Kansas, 1251 Wescoe Hall Drive, Lawrence, KS 66045, USA.
authors: Naeem
authors: N
authors: Asad
authors: Paul R
authors: PR
authors: Hanson
authors: Toby R
authors: TR
authors: Long
authors: Dinesh K
authors: DK
authors: Rayabarapu
authors: Alan
authors: A
authors: Rolfe
mesh_terms: D002384:Catalysis; D010084:Oxidation-Reduction; D010087:Oxides / Q000138:chemical synthesis / Q000737:chemistry*; D058105:Polymerization; D012825:Silicon / Q000737:chemistry; D013844:Thiazoles / Q000737:chemistry*
chemical_list: D010087:Oxides; D013844:Thiazoles; D012825:Silicon