title: Ion-tuned DNA/Ag fluorescent nanoclusters as versatile logic device.
abstract: A novel kind of versatile logic device has been constructed utilizing ion-tuned DNA/Ag fluorescent nanoclusters, with K(+) and H(+) as two inputs. A well-chosen hairpin DNA with a poly-C loop serves as the template for synthesizing two species of Ag nanoclusters. Several G-tracts and C-tracts on its two terminals enable the hairpin DNA to convert into the G-quadruplex and/or i-motif structures upon input of K(+) and H(+). Such a structural change remarkably influences the spectral behaviors of Ag nanoclusters. In particular, different species of Ag nanoclusters have distinct fluorescence responses to the input of K(+) and H(+). These unique features of DNA/Ag nanoclusters enable multiple logic operations via multichannel fluorescence output, indicating the versatility as a molecular logic device. By altering the specific sequence of the hairpin DNA, more logic gates can be constructed utilizing Ag nanoclusters.
authors: State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130022, China.
authors: Tao
authors: T
authors: Li
authors: Libing
authors: L
authors: Zhang
authors: Jun
authors: J
authors: Ai
authors: Shaojun
authors: S
authors: Dong
authors: Erkang
authors: E
authors: Wang
mesh_terms: D001483:Base Sequence; D039301:Computers, Molecular; D004247:DNA / Q000737:chemistry* / Q000235:genetics; D005456:Fluorescent Dyes / Q000737:chemistry*; D054856:G-Quadruplexes; D055029:Inverted Repeat Sequences; D008128:Logic; D049329:Nanostructures / Q000737:chemistry*; D059372:Nucleotide Motifs; D012834:Silver / Q000737:chemistry*; D013050:Spectrometry, Fluorescence
chemical_list: D005456:Fluorescent Dyes; D012834:Silver; D004247:DNA