title: [Prediction of bone strength using a quantitative computed tomography based finite element method].
abstract: Clinically available methods for estimating bone strength include bone densitometry techniques such as dual energy X-ray absorptiometry and quantitative computed tomography, and other diagnostic imaging procedures such as radiographic imaging. These techniques evaluate regional bone density and morphology, which are partly related to fracture risk, but are of limited value for quantifying structural strength. Therefore, it is necessary to develop a noninvasive method for accurate quantitative structural analysis that incorporates information on both morphology and bone density in a three-dimensional distribution. Computed tomography-based finite element method (CT/FEM), which incorporates information on both the three-dimensional architecture and bone density distribution, could possibly achieve precise assessment of the strength of the bone. We focused on a CT/FEM to quantify structural strength, developing a nonlinear CT/FEM to achieve accurate assessment of strength in the proximal femur and lumbar vertebrae. Here, we describe the CT/FEM.
authors: Department of Orthopaedic surgery, Kaken Hospital, Clinical Medical Research Center, International University of Health and Welfare.
authors: Masahiko
authors: M
authors: Bessho
authors: Isao
authors: I
authors: Ohnishi
authors: Masako
authors: M
authors: Kaneko
authors: Satoru
authors: S
authors: Ohashi
authors: Kenji
authors: K
authors: Tobita
authors: Takuya
authors: T
authors: Matsumoto
authors: Kazuhiro
authors: K
authors: Imai
authors: Kozo
authors: K
authors: Nakamura
mesh_terms: D001842:Bone and Bones / Q000000981:diagnostic imaging* / Q000502:physiology*; D020342:Finite Element Analysis; D005544:Forecasting; D006801:Humans; D012306:Risk; D013718:Tensile Strength; D014057:Tomography, X-Ray Computed / Q000379:methods*