title: Surgical resection of locally advanced pulmonary adenocarcinoma after gefitinib therapy.
abstract: First-line therapy with gefitinib prolongs progression-free survival and improves quality of life among selected patients with non-small cell lung cancer. Selected locally advanced patients may derive benefit from surgical resection after gefitinib therapy. Further clinical trials are needed to evaluate the role of gefitinib therapy followed by surgical resection.
authors: Department of Thoracic Surgery, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.
authors: Ming
authors: M
authors: Liu
authors: Gening
authors: G
authors: Jiang
authors: Wenxin
authors: W
authors: He
authors: Peng
authors: P
authors: Zhang
authors: Nan
authors: N
authors: Song
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis / Q000188:drug therapy* / Q000235:genetics / Q000601:surgery*; D000284:Administration, Oral; D001707:Biopsy, Needle; D005260:Female; D005500:Follow-Up Studies; D000077156:Gefitinib; D018773:Genes, erbB-1 / Q000187:drug effects; D006801:Humans; D007150:Immunohistochemistry; D008175:Lung Neoplasms / Q000175:diagnosis / Q000188:drug therapy* / Q000235:genetics / Q000601:surgery*; D008875:Middle Aged; D020360:Neoadjuvant Therapy / Q000379:methods; D009361:Neoplasm Invasiveness / Q000473:pathology; D009367:Neoplasm Staging; D011013:Pneumonectomy / Q000379:methods*; D049268:Positron-Emission Tomography / Q000379:methods; D011799:Quinazolines / Q000008:administration & dosage*; D018570:Risk Assessment; D014057:Tomography, X-Ray Computed / Q000379:methods; D016896:Treatment Outcome
chemical_list: D011799:Quinazolines; D000077156:Gefitinib