title: Improved metal cluster deposition on a genetically engineered tobacco mosaic virus template.
abstract: Improved depositions of various metal clusters onto a biomolecular template were achieved using a genetically engineered tobacco mosaic virus (TMV). Wild-type TMV was genetically altered to display multiple solid metal binding sites through the insertion of two cysteine residues within the amino-terminus of the virus coat protein. Gold, silver, and palladium clusters synthesized through in situ chemical reductions could be readily deposited onto the genetically modified template via the exposed cysteine-derived thiol groups. Metal cluster coatings on the cysteine-modified template were more densely deposited and stable than similar coatings on the unmodified wild-type template. Combined, these results confirm that the introduction of cysteine residues onto the outer surface of the TMV coat protein enhances the usefulness of this virus as a biotemplate for the deposition of metal clusters.
authors: School of Chemical Engineering, Purdue University, West Lafayette, IN 47907, USA.
authors: Sang-Yup
authors: SY
authors: Lee
authors: Elizabeth
authors: E
authors: Royston
authors: James N
authors: JN
authors: Culver
authors: Michael T
authors: MT
authors: Harris