title: Time-resolved three-dimensional magnetic resonance velocity mapping of chronic thoracic aortic dissection: a preliminary investigation.
abstract: OBJECTIVE
  The blood flow patterns of chronic thoracic aortic dissection are complicated, and their clinical significance remains unknown. We evaluated the technical and clinical potentials of time-resolved 3-dimensional (3D) magnetic resonance (MR) velocity mapping for assessing these patterns.
  
  
  METHODS
  We used data collected from time-resolved 3D phase-contrast MR imaging of 16 patients with chronic thoracic aortic dissection to generate time-resolved 3D MR velocity mapping that included 3D streamline and path line. We investigated blood flow patterns of this disease in the mapping and compared them with the morphological changes of the patent false lumen.
  
  
  RESULTS
  Time-resolved 3D MR velocity mapping visualized rapid flow at the entry and in the true lumen immediately distal to the entry. We observed slower helical or laminar flow in the patent false lumen. In patients with disease progression, slower helical flow following rapid entry jet collided with the outer wall of the false lumen and was also observed in a growing ulcer-like projection.
  
  
  CONCLUSIONS
  We showed the potential of time-resolved 3D MR velocity mapping for visualizing pathologic flow patterns related to chronic thoracic aortic dissection.
authors: Department of Radiology, Nippon Medical School, Tokyo, Japan. yas-amano@nifty.com
authors: Yasuo
authors: Y
authors: Amano
authors: Tetsuro
authors: T
authors: Sekine
authors: Yuriko
authors: Y
authors: Suzuki
authors: Keiji
authors: K
authors: Tanaka
authors: Ryo
authors: R
authors: Takagi
authors: Shinichiro
authors: S
authors: Kumita
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000784:Aortic Dissection / Q000503:physiopathology* / Q000601:surgery; D017545:Aortic Aneurysm, Thoracic / Q000503:physiopathology* / Q000601:surgery; D001783:Blood Flow Velocity; D002908:Chronic Disease; D003287:Contrast Media; D018450:Disease Progression; D005260:Female; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D021621:Imaging, Three-Dimensional / Q000379:methods*; D018810:Magnetic Resonance Angiography / Q000379:methods*; D008297:Male; D008875:Middle Aged
chemical_list: D003287:Contrast Media