title: Comparison of the compression anastomosis ring (EndoCAR) with a circular stapled anastomosis in a porcine model.
abstract: OBJECTIVE
  The aim of this study was to compare characteristics of rectal compression and stapled anastomoses at multiple time points.
  
  
  METHODS
  A total of 50 domestic pigs underwent a rectal anastomosis with a compression device or a circular stapler. They were sacrificed at zero-time, 2 days, 1 week, 1 month, and 3 months. Burst and maximal tolerated pressure and sites of failure, internal diameters, and radiographic leak rates were assessed. Desmosine (elastin) levels were determined.
  
  
  RESULTS
  There were no clinical or radiographic leaks. Overall, 10 out of 27 (37%) compression anastomoses burst at higher pressures than the 14 out of 24 (58%) stapled anastomoses. Mean circumference and anastomotic index were greater for the EndoCAR at 1 week and 3 months. Desmosine levels were similar.
  
  
  CONCLUSIONS
  In the porcine model, compression rectal anastomoses with the EndoCAR had improved bursting pressures and internal circumference compared with circular stapled anastomoses.
authors: Tuckson Colorectal Surgery, Louisville, KY, USA.
authors: Jonathan
authors: J
authors: Chun
authors: Dooseok
authors: D
authors: Lee
authors: David
authors: D
authors: Stewart
authors: Michael
authors: M
authors: Talcott
authors: James
authors: J
authors: Fleshman
mesh_terms: D000714:Anastomosis, Surgical / Q000295:instrumentation*; D000818:Animals; D016009:Chi-Square Distribution; D004867:Equipment Design; D005260:Female; D008422:Materials Testing; D023421:Models, Animal; D011312:Pressure; D012007:Rectum / Q000601:surgery*; D013528:Surgical Staplers; D013536:Suture Techniques / Q000295:instrumentation*; D013552:Swine