title: Torque teno sus virus 1 and 2 viral loads in postweaning multisystemic wasting syndrome (PMWS) and porcine dermatitis and nephropathy syndrome (PDNS) affected pigs.
abstract: Torque teno viruses (TTV) are small, non-enveloped viruses with a circular single-stranded DNA genome, which are considered non-pathogenic. However, TTVs have been eventually linked to human diseases. TTVs infecting pigs, Torque teno sus virus 1 (TTSuV1) and 2 (TTSuV2), have been recently associated to porcine circovirus diseases (PCVD). To get more insights into such potential disease association, the aim of this study was to quantify TTSuV1 and TTSuV2 viral loads in serum of pigs affected by two PCVDs, postweaning multisystemic wasting syndrome (PMWS) and porcine dermatitis and nephropathy syndrome (PDNS). Such study was carried out by means of a newly developed real-time quantitative PCR (qPCR) method. Both TTSuVs were highly prevalent among studied pigs. TTSuV2 viral loads were significantly higher in PMWS affected animals, further supporting the previously suggested association between TTSuV2 and PMWS. On the contrary, TTSuV1 prevalence and loads were not related with the studied PCVDs.
authors: Centre de Recerca en Sanitat Animal (CReSA), UAB-IRTA, Campus de la Universitat Autònoma de Barcelona, 08193 Bellaterra, Barcelona, Spain.
authors: M
authors: M
authors: Aramouni
authors: J
authors: J
authors: Segalés
authors: M
authors: M
authors: Sibila
authors: G E
authors: GE
authors: Martin-Valls
authors: D
authors: D
authors: Nieto
authors: T
authors: T
authors: Kekarainen
mesh_terms: D000818:Animals; D018173:Circoviridae Infections / Q000821:virology; D003872:Dermatitis / Q000821:virology; D006801:Humans; D053570:Porcine Postweaning Multisystemic Wasting Syndrome / Q000821:virology*; D060888:Real-Time Polymerase Chain Reaction / Q000662:veterinary; D013552:Swine; D013553:Swine Diseases / Q000821:virology*; D022783:Torque teno virus / Q000235:genetics / Q000502:physiology*; D019562:Viral Load / Q000662:veterinary*