title: A case of fibroelastolytic papulosis on the neck of a young man.
abstract: Fibroelastolytic papulosis of the neck (FEPN) encompasses a spectrum of two disorders that were previously reported as pseudoxanthoma elasticum-like papillary dermal elastolysis (PXE-PDE) and white fibrous papulosis of the neck (WFPN). The clinical presentation of FEPN is asymptomatic to mildly pruritic whitish-yellow papules that may coalesce into cobblestone patterned plaques that resemble pseudoxanthoma elasticum (PXE). The histology is characterized by a decrease or loss of elastic fibers in the papillary dermis and this is sometimes accompanied by a minimal or nodular increase of dermal collagen fibers. We report here on a 28-year-old Korean man with asymptomatic, multiple, skin-colored to slightly yellowish, match-head sized, cobblestone-patterned papules on the neck, and these were histologically consistent with FEPN and the papules showed slightly increased dermal collagen associated with decreased and fragmented elastic fibers, elastin and tropoelastin. The pathogenesis of FEPN in this case might have been related with mild dermal inflammation, followed by fragmentation, elastolysis and increased dermal collagen.
authors: Department of Dermatology, Konkuk University School of Medicine, Seoul, Korea.
authors: Young Chan
authors: YC
authors: Song
authors: Byung Ho
authors: BH
authors: Oh
authors: Jong Hyun
authors: JH
authors: Ko
authors: Ji Young
authors: JY
authors: Kim
authors: Young Ji
authors: YJ
authors: Hwang
authors: Yang Won
authors: YW
authors: Lee
authors: Yong Beom
authors: YB
authors: Choe
authors: Kyu Joong
authors: KJ
authors: Ahn
authors: Kyae Yong
authors: KY
authors: Song