title: Phakic anterior chamber lenses in very high myopia: an 18-month follow up.
abstract: BACKGROUND
  To evaluate the efficacy and tolerance of two different foldable anterior chamber phakic intraocular lenses for high myopia.
  
  
  METHODS
  A prospective interventional case series at the Eye Clinic, Kartal Training and Research Hospital, Istanbul, Turkey.
  
  
  METHODS
  Sixty-two eyes of 31 patients received iris-claw lens (group 1) (Artiflex AC 401, Ophtec), and 43 eyes of 22 patients received angle-supported lens (group 2) (I-Care, Corneal).
  
  
  METHODS
  The mean preoperative spherical equivalents for group 1 and group 2 were -12.13 D and -18.95 D, respectively. Endothelial cell density was measured at day 1 and at 1, 3, 6, 12 and 18 months for follow ups.
  
  
  METHODS
  Percentage change in endothelial cell density and improvement in visual acuity.
  
  
  RESULTS
  At the 18-months follow up, uncorrected visual acuity improved to logMAR 0.37 ± 0.23 from 1.60 ± 0.10 in group 1, and logMAR 0.47 ± 0.14 from 0.70 ± 0.20 in group 2; best spectacle corrected visual acuity improved to logMAR 0.23 ± 0.22 from logMAR 0.36 ± 0.14) in group 1, and logMAR 0.29 ± 0.18 from logMAR 0.50 ± 0.20) in group 2 (P<0.001, in both groups). Mean decreased endothelial cell density was 241 cells/mm(2) (8.61%) and 223 cells/mm(2) (8.42%) at 18 months follow up in group 1 and 2, respectively (P=0.17) but significant in comparison to preoperative values for both groups (P<0.001).
  
  
  CONCLUSIONS
  Although both iris-claw and angle-supported lenses offer good refractive outcomes significant endothelial cell density was observed at 18 months follow up.
authors: Dr Lutfi Kirdar Kartal Training and Research Hospital, Eye Clinic Acibadem Hospital, Maslak, Istanbul.
authors: Levent
authors: L
authors: Akcay
authors: Ilker
authors: I
authors: Eser
authors: Aysin T
authors: AT
authors: Kaplan
authors: Arzu
authors: A
authors: Taskiran-Comez
authors: Omer K
authors: OK
authors: Dogan
mesh_terms: D000293:Adolescent; D000328:Adult; D000867:Anterior Chamber / Q000601:surgery*; D002452:Cell Count; D055954:Corneal Endothelial Cell Loss / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D019654:Lens Implantation, Intraocular; D008297:Male; D008875:Middle Aged; D047728:Myopia, Degenerative / Q000503:physiopathology / Q000601:surgery*; D054120:Phakic Intraocular Lenses; D011183:Postoperative Complications; D011446:Prospective Studies; D016896:Treatment Outcome; D014792:Visual Acuity / Q000502:physiology; D055815:Young Adult