title: Pharmacogenetics and pharmacogenomics: a clinical reality.
abstract: Pharmacogenetics and pharmacogenomics strive to explain the interindividual variability in response to drugs due to genetic variation. For certain drugs, genetic tests can reduce adverse drug reactions and improve treatment efficacy. In this review, we will briefly consider some successful tests introduced into clinical practice and potential future developments.
authors: Department of Medical Oncology, Christie Hospital NHS Trust, Manchester M20 4BX, UK.
authors: Roberta
authors: R
authors: Ferraldeschi
authors: William G
authors: WG
authors: Newman
mesh_terms: D001711:Biotransformation / Q000235:genetics*; D004305:Dose-Response Relationship, Drug; D004342:Drug Hypersensitivity / Q000235:genetics*; D006801:Humans; D058990:Molecular Targeted Therapy; D009369:Neoplasms / Q000188:drug therapy / Q000235:genetics / Q000378:metabolism; D010597:Pharmacogenetics