title: Emerging technologies for the prevention of dental caries. Are current methods of prevention sufficient for the high risk patient?
abstract: Fluorides and chlorhexidine are technologies that are 65 and 40 years old, respectively. This overview argues that current methods of caries prevention are not effective for the high caries risk patient. In this review examples, arguments and recommendations are provided to address the high caries risk patient that include: failure of comprehensive chemical modalities treatments to address the high caries risk patient; ecological alteration - would this be an effective approach?; and biomaterials and oral microbiome research to address the high caries risk patient.
authors: New York University College of Dentistry, New York, NY 10010, USA. wb36@nyu.edu
authors: Walter A
authors: WA
authors: Bretz
authors: Odila P S
authors: OP
authors: Rosa
mesh_terms: D000891:Anti-Infective Agents, Local / Q000627:therapeutic use; D002327:Cariostatic Agents / Q000627:therapeutic use; D002710:Chlorhexidine / Q000627:therapeutic use; D003731:Dental Caries / Q000382:microbiology* / Q000517:prevention & control*; D016503:Drug Delivery Systems; D005260:Female; D054884:Host-Pathogen Interactions / Q000235:genetics*; D006801:Humans; D007223:Infant; D018445:Infectious Disease Transmission, Vertical / Q000517:prevention & control; D054892:Metagenome; D011247:Pregnancy; D016032:Randomized Controlled Trials as Topic; D012306:Risk; D012471:Salivary Proteins and Peptides / Q000235:genetics; D013295:Streptococcus mutans / Q000235:genetics / Q000378:metabolism
chemical_list: D000891:Anti-Infective Agents, Local; D002327:Cariostatic Agents; D012471:Salivary Proteins and Peptides; D002710:Chlorhexidine