title: The role of dynamic, contrast-enhanced MRI in differentiating lung tumor subtypes.
abstract: The aim was to correlate dynamic magnetic resonance imaging perfusion parameters of pulmonary tumors with histological tumor classification. Eighty-six patients with lung cancer were examined. A differentiation of non-small cell lung cancer vs. small cell lung cancer was possible with the parameters tumor necrosis, maximum contrast upslope, and the time until the maximum contrast upslope was reached. The beginning of a relevant contrast uptake, the mean time to peak and the time until the maximum contrast upslope was reached allowed a differentiation between squamous cell carcinoma and adenocarcinoma.
authors: Department of Radiology and Nuclear Medicine, Sana Hospitals Lübeck, Kronsforder Allee 71-73, 23560 Lübeck, Germany. sandra.pauls@t-online.de
authors: Sandra
authors: S
authors: Pauls
authors: Thomas
authors: T
authors: Breining
authors: Rainer
authors: R
authors: Muche
authors: Stefan A
authors: SA
authors: Schmidt
authors: Arthur
authors: A
authors: Wunderlich
authors: S
authors: S
authors: Krüger
authors: Hans-Jürgen
authors: HJ
authors: Brambs
authors: Sebastian
authors: S
authors: Feuerlein
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology; D000077192:Adenocarcinoma of Lung; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001706:Biopsy; D002289:Carcinoma, Non-Small-Cell Lung / Q000473:pathology; D002294:Carcinoma, Squamous Cell / Q000473:pathology; D016009:Chi-Square Distribution; D003287:Contrast Media; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D016015:Logistic Models; D008175:Lung Neoplasms / Q000473:pathology*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009942:Organometallic Compounds; D011446:Prospective Studies; D012372:ROC Curve; D055752:Small Cell Lung Carcinoma / Q000473:pathology
chemical_list: D003287:Contrast Media; D009942:Organometallic Compounds; C090600:gadobutrol