title: Physical association of pattern-triggered immunity (PTI) and effector-triggered immunity (ETI) immune receptors in Arabidopsis.
abstract: Plants possess two distinct types of immune receptor. The first type, pattern recognition receptors (PRRs), recognizes microbe-associated molecular patterns (MAMPs) and initiates pattern-triggered immunity (PTI) on recognition. FLS2 is a PRR, which recognizes a part of bacterial flagellin. The second type, resistance (R) proteins, recognizes pathogen effectors and initiates effector-triggered immunity (ETI) on recognition. RPM1, RPS2 and RPS5 are R proteins. Here, we provide evidence that FLS2 is physically associated with all three R proteins. Our findings suggest that signalling interactions occur between PTI and ETI at very early stages and/or that FLS2 forms a PTI signalling complex, some components of which are guarded by R proteins.
authors: Department of Plant Biology, Microbial and Plant Genomics Institute, University of Minnesota, St. Paul, MN 55108, USA.
authors: Yiping
authors: Y
authors: Qi
authors: Kenichi
authors: K
authors: Tsuda
authors: Jane
authors: J
authors: Glazebrook
authors: Fumiaki
authors: F
authors: Katagiri
mesh_terms: D017360:Arabidopsis / Q000235:genetics / Q000378:metabolism* / Q000382:microbiology; D029681:Arabidopsis Proteins / Q000235:genetics / Q000378:metabolism*; D002352:Carrier Proteins / Q000235:genetics / Q000378:metabolism; D002462:Cell Membrane / Q000378:metabolism; D047908:Intracellular Signaling Peptides and Proteins; D011485:Protein Binding; D011494:Protein Kinases / Q000235:genetics / Q000378:metabolism*; D051192:Receptors, Pattern Recognition / Q000235:genetics / Q000378:metabolism*
chemical_list: D029681:Arabidopsis Proteins; D002352:Carrier Proteins; D047908:Intracellular Signaling Peptides and Proteins; C453279:RIN4 protein, Arabidopsis; C095014:RPM1 protein, Arabidopsis; C089426:RPS2 protein, Arabidopsis; C465630:RPS5 protein, Arabidopsis; D051192:Receptors, Pattern Recognition; D011494:Protein Kinases; C411853:FLS2 protein, Arabidopsis