title: Antifungal activity of sakurasosaponin from the root extract of Jacquinia flammea.
abstract: The methanolic crude extract from the roots of Jacquinia flammea showed moderate antifungal activity against dermatophytes and very strong antifungal activity against Colletotrichum gloeosporioides. The bioassay-guided purification of the extract, using a combination of vacuum-liquid chromatography and high performance liquid chromatography, allowed the identification of sakurasosaponin as the main metabolite responsible for the antifungal activity.
authors: Unidad de Biotecnología, Centro de Investigación Científica de Yucatán, Calle 43 No. 130 Col. Chuburná de Hidalgo, Mérida, Yucatán, 97200 México.
authors: K
authors: K
authors: García-Sosa
authors: A
authors: A
authors: Sánchez-Medina
authors: Sandra L
authors: SL
authors: Álvarez
authors: S
authors: S
authors: Zacchino
authors: N C
authors: NC
authors: Veitch
authors: P
authors: P
authors: Simá-Polanco
authors: L M
authors: LM
authors: Peña-Rodriguez
mesh_terms: D000935:Antifungal Agents / Q000032:analysis / Q000737:chemistry / Q000494:pharmacology*; D003883:Arthrodermataceae / Q000187:drug effects; D002853:Chromatography, Liquid; D020231:Colletotrichum / Q000187:drug effects; D000432:Methanol; D015394:Molecular Structure; D010936:Plant Extracts / Q000032:analysis / Q000737:chemistry / Q000494:pharmacology*; D018517:Plant Roots / Q000737:chemistry*; D029623:Primulaceae / Q000737:chemistry*; D012503:Saponins / Q000032:analysis / Q000737:chemistry / Q000494:pharmacology*
chemical_list: D000935:Antifungal Agents; D010936:Plant Extracts; D012503:Saponins; C549307:sakurasosaponin; D000432:Methanol