title: Recommendation for use of the newly introduced pneumococcal protein conjugate vaccines in Korea.
abstract: Streptococcus pneumoniae remains a leading cause of invasive infections including bacteremia and meningitis, as well as mucosal infections such as otitis media and pneumonia among children and adults. The 7-valent pneumococcal conjugate vaccine (PCV7) was licensed for use among infants and young children in many countries including Korea. The routine use of PCV7 has resulted in a decreased incidence of invasive pneumococcal disease (IPD) by the vaccine serotypes among the vaccinees and substantial declines in IPD among unvaccinated populations such as older children and adults as well. In addition, there are increasing evidences to suggest that routine immunization with PCV7 is changing the epidemiology of pneumococcal diseases such as serotype distribution of IPD, nasopharyngeal colonization, and antibiotic resistance patterns. In contrast, there is an increase in the number of IPDs caused by nonvaccine serotypes, though it is much smaller than overall declines of vaccine serotype diseases. Several vaccines containing additional serotypes have been developed and tested clinically in order to expand the range of serotypes of Streptococcus pneumoniae. Recently two new pneumococcal protein conjugate vaccines, 10-valent pneumococcal conjugate vaccine (PCV10) and 13-valent pneumococcal conjugate vaccine (PCV13), have been approved for use in several countries including Korea. This report summarizes the recommendations approved by the Committee on Infectious Diseases, the Korean Pediatric Society.
authors: The Committee on Infectious Diseases, the Korean Pediatric Society, Korea.
authors: Eun Hwa
authors: EH
authors: Choi
authors: Kyung Hyo
authors: KH
authors: Kim
authors: Yae Jean
authors: YJ
authors: Kim
authors: Jong Hyun
authors: JH
authors: Kim
authors: Su Eun
authors: SE
authors: Park
authors: Hoan Jong
authors: HJ
authors: Lee
authors: Byung Wook
authors: BW
authors: Eun
authors: Dae Sun
authors: DS
authors: Jo
authors: Kyong Min
authors: KM
authors: Choi
authors: Young Jin
authors: YJ
authors: Hong