title: Diabetic dyslipidaemia in Asian populations in the Western Pacific Region: what we know and don't know.
abstract: Approximately 77 million persons with diabetes reside in the Western Pacific Region. This number is estimated to rise to 113 million in 2030 with increasing burden of cardio-renal disease, affecting an increasingly young population. Randomized clinical trials have confirmed the benefits of using statins to reduce low-density lipoprotein cholesterol in preventing cardiovascular disease (CVD) in Caucasians, although similar data are lacking in Asia. Experts from the Western Pacific Region met and reviewed evidence regarding risk association of diabetic dyslipidaemia with cardio-renal disease, effects of lipid lowering, recommended guidelines and clinical practices in Asian populations. There is strong evidence supporting the role of diabetic dyslipidaemia in cardio-renal disease and the benefits of lipid lowering in these populations. The high rate of diabetic kidney disease, its close links with CVD, and the benefits of lipid lowering on renal function are particularly relevant to this population. While most national guidelines use criteria similar to the West in management of diabetic dyslipidaemia, there are consistently low rates of use of lipid-lowering drugs and attaining treatment goals in the region. The group recommends conducting randomized studies, strengthening of the health care system to promote early detection, and intervention of diabetic dyslipidaemia to prevent end organ damage.
authors: Hong Kong Institute of Diabetes and Obesity and Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, NT, Hong Kong Special Administrative Region. jchan@cuhk.edu.hk
authors: Juliana C N
authors: JC
authors: Chan
authors: Siew Pheng
authors: SP
authors: Chan
authors: Chaicharn
authors: C
authors: Deerochanawong
authors: Ruby T
authors: RT
authors: Go
authors: Kok-Onn
authors: KO
authors: Lee
authors: Ronald Ching-Wan
authors: RC
authors: Ma
authors: Chang-Yu
authors: CY
authors: Pan
authors: Wayne H-H
authors: WH
authors: Sheu
authors: Philip
authors: P
authors: Barter
mesh_terms: D000818:Animals; D044466:Asian People; D002318:Cardiovascular Diseases / Q000378:metabolism; D003920:Diabetes Mellitus / Q000378:metabolism*; D050171:Dyslipidemias / Q000378:metabolism*; D005260:Female; D006801:Humans; D008297:Male