title: Microwave-assisted multicomponent reaction in water leading to highly regioselective formation of benzo[f]azulen-1-ones.
abstract: Microwave-assisted three-component reaction has been established for the regioselective synthesis of benzo[f]azulen-1-ones. The reaction was performed in aqueous media under microwave irradiation by using readily available and inexpensive starting materials. A total of 38 examples were examined to show a broad substrate scope and good overall yields (70-89%). The present new synthesis shows attractive green chemistry characteristics, such as the use of water as reaction media, concise one-pot conditions, short reaction periods (7-24 min), easy work-up/purification and reduced waste production without the use of any strong acids or metal promoters.
authors: School of Chemistry and Chemical Engineering, Laboratory of Green Synthetic Chemistry for Functional Materials. Xuzhou Normal University; Xuzhou 221116, Jiangsu, P. R. China.
authors: Shu-Liang
authors: SL
authors: Wang
authors: Chuang
authors: C
authors: Cheng
authors: Fei-Yue
authors: FY
authors: Wu
authors: Bo
authors: B
authors: Jiang
authors: Feng
authors: F
authors: Shi
authors: Shu-Jiang
authors: SJ
authors: Tu
authors: Trideep
authors: T
authors: Rajale
authors: Guigen
authors: G
authors: Li