title: [State-dependent motivational interviewing for people with schizophrenia and substance use: results of a randomised controlled trial].
abstract: BACKGROUND
  Comorbid substance use disorder in patients with schizophrenia is associated with poor clinical and social outcome and low compliance with integrated outpatient treatment programs. For the first time the present trial compares the efficacy of four sessions of motivational interviewing (MI) and four sessions of supportive therapy (ST). The primary outcome was compliance with integrated outpatient treatment post-intervention. Secondary outcomes were substance use, psychopathology, compliance with medication and stage of change in psychotherapy.
  
  
  METHODS
  Sixty inpatients with schizophrenia and substance use disorder were randomised to receive either four sessions of MI or four sessions of ST. Masked assessments took place at baseline, post-treatment and 3- and 6-month follow-ups.
  
  
  RESULTS
  The integrated outpatient program was attended by 70.0% of the MI (n=30) and 40.0% of the ST patients (n=30; p=0.020). There were no differences regarding secondary outcome between MI and ST groups.
  
  
  CONCLUSIONS
  The study design allows one for the first time to attribute the findings to the specific effects of MI and thereby emphasizes the effectiveness of this particular treatment approach. In summary, these findings show that the integration of short-term MI for people with both psychosis and substance abuse could significantly improve their chances of attending appropriate outpatient settings and thereby improve their well-being.
authors: Klinik und Poliklinik für Psychiatrie und Psychotherapie, Uniklinik Köln, Kerpener Str. 62, 50937 Köln, Deutschland. andreas.bechdolf@uk-koeln.de
authors: A
authors: A
authors: Bechdolf
authors: B
authors: B
authors: Pohlmann
authors: J
authors: J
authors: Güttgemanns
authors: C
authors: C
authors: Geyer
authors: K
authors: K
authors: Lindner
authors: C
authors: C
authors: Ferber
authors: E
authors: E
authors: Gouzoulis-Mayfrank
mesh_terms: D000293:Adolescent; D000328:Adult; D015928:Cognitive Behavioral Therapy / Q000379:methods*; D005260:Female; D006801:Humans; D007406:Interview, Psychological / Q000379:methods*; D007407:Interviews as Topic; D008297:Male; D009042:Motivation; D012559:Schizophrenia / Q000150:complications* / Q000628:therapy*; D019966:Substance-Related Disorders / Q000150:complications* / Q000628:therapy*; D016896:Treatment Outcome; D055815:Young Adult