title: Aminoindanes--the next wave of 'legal highs'?
abstract: Due to its closed ring system, 2-aminoindane is a conformationally rigid analogue of amphetamine. Internet websites offering synthetic compounds as 'research chemicals' have recently been advertising 5,6-methylenedioxy-2-aminoindane (MDAI), 5, 6-methylenedioxy-N-methyl-2-aminoindane (MDMAI), 5-iodo-2-aminoindane (5-IAI), and 5-methoxy-6-methyl-2-aminoindane (MMAI). The chemistry, pharmacology, and toxicological aspects of this new class of psychoactive substances are reviewed, as these could become the next wave of 'legal highs'.
authors: Department of Forensic Science and Drug Monitoring, Franklin-Wilkins Building, King's College London SE1 9 NH, UK.
authors: P D
authors: PD
authors: Sainsbury
authors: A T
authors: AT
authors: Kicman
authors: R P
authors: RP
authors: Archer
authors: L A
authors: LA
authors: King
authors: R A
authors: RA
authors: Braithwaite
mesh_terms: D000588:Amines / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D000818:Animals; D006801:Humans; D013287:Illicit Drugs / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D007189:Indans / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D018377:Neurotransmitter Agents / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*
chemical_list: D000588:Amines; D013287:Illicit Drugs; D007189:Indans; D018377:Neurotransmitter Agents