title: Megahertz streak-mode Fourier domain optical coherence tomography.
abstract: Here we present an ultrahigh-speed Fourier-domain optical coherence tomography (OCT) that records the OCT spectrum in streak mode with a high-speed area scan camera, which allows higher OCT imaging speed than can be achieved with a line-scan camera. Unlike parallel OCT techniques that also use area scan cameras, the conventional single-mode fiber-based point-scanning mechanism is retained to provide a confocal gate that rejects multiply scattered photons from the sample. When using a 1000 Hz resonant scanner as the streak scanner, 1,016,000 A-scans have been obtained in 1 s. This method's effectiveness has been demonstrated by recording in vivo OCT-image sequences of embryonic chick hearts at 1000 frames/s. In addition, 2-megahertz OCT data have been obtained with another high speed camera.
authors: Clemson University, Department of Bioengineering, COMSET, Clemson, South Carolina 29634, USA.
authors: Rui
authors: R
authors: Wang
authors: Julie X
authors: JX
authors: Yun
authors: Xiaocong
authors: X
authors: Yuan
authors: Richard
authors: R
authors: Goodwin
authors: Roger R
authors: RR
authors: Markwald
authors: Bruce Z
authors: BZ
authors: Gao
mesh_terms: D000465:Algorithms; D000818:Animals; D002642:Chick Embryo; D004867:Equipment Design; D005583:Fourier Analysis; D006321:Heart / Q000033:anatomy & histology / Q000196:embryology; D007368:Interferometry; D019697:Onions / Q000033:anatomy & histology; D041623:Tomography, Optical Coherence / Q000379:methods*