title: Burkholderia pseudomallei infection in a child with cystic fibrosis: acquisition in the Western Hemisphere.
abstract: Melioidosis, an infection caused by the bacterium Burkholderia pseudomallei, is endemic to Southeast Asia and northern Australia but is only very rarely seen in patients in the United States. We report pulmonary B pseudomallei infection in a young girl with cystic fibrosis (CF) who had never traveled to Asia or Australia. Biochemical and epidemiologic investigation determined Aruba as the likely site of disease acquisition. This report highlights the ability of patients with CF to acquire this organism outside of Southeast Asia and describes an aggressive treatment regimen that has kept this patient culture-negative for the organism over a long period of time.
authors: Department of Pediatrics, University of Massachusetts Medical School and UMass Memorial Health Care, Worcester, MA. Electronic address: osullivb@ummhc.org.
authors: Brian P
authors: BP
authors: O'Sullivan
authors: Department of Laboratory Sciences, UMass Memorial Health Care, Worcester, MA.
authors: Brenda
authors: B
authors: Torres
authors: Division of Epidemiology and Immunization, Bureau of Infectious Diseases, Massachusetts Department of Public Health, Jamaica Plain, MA.
authors: Giuseppe
authors: G
authors: Conidi
authors: Bureau of Laboratory Sciences, William A. Hinton State Laboratory Institute, Massachusetts Department of Public Health, Jamaica Plain, MA.
authors: Sandra
authors: S
authors: Smole
authors: Bureau of Laboratory Sciences, William A. Hinton State Laboratory Institute, Massachusetts Department of Public Health, Jamaica Plain, MA.
authors: Cheryl
authors: C
authors: Gauthier
authors: Department of Agriculture, Animal Plant Health Inspection Service/Veterinary Service, Gainesville, FL.
authors: Kendra E
authors: KE
authors: Stauffer
authors: Bacterial Special Pathogens Branch, Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA.
authors: Mindy B
authors: MB
authors: Glass
authors: Bacterial Special Pathogens Branch, Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA.
authors: Jay E
authors: JE
authors: Gee
authors: Bacterial Special Pathogens Branch, Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA.
authors: David
authors: D
authors: Blaney
authors: Bacterial Special Pathogens Branch, Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA.
authors: Theresa L
authors: TL
authors: Smith
mesh_terms: D016957:Burkholderia pseudomallei / Q000302:isolation & purification*; D002648:Child; D003550:Cystic Fibrosis / Q000150:complications*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008554:Melioidosis / Q000150:complications* / Q000175:diagnosis / Q000382:microbiology; D009894:Opportunistic Infections / Q000150:complications* / Q000175:diagnosis / Q000382:microbiology; D013902:Radiography, Thoracic; D013183:Sputum / Q000382:microbiology*