title: [Meta-analysis of proximal gastrectomy and total gastrectomy for cancer of cardia and fundus].
abstract: OBJECTIVE
  To assess the value of proximal gastrectomy (PG) and total gastrectomy (TG) for the treatment of cancer of cardia and fundus.
  
  
  METHODS
  Publications on comparision between PG and TG in the treatment of cancer of cardia and fundus were collected, the data from the publications were matched with the PG group and the TG group respectively according to its corresponding surgical resection, and the data on postoperative complications, motality and 5-year survival rate were meta-analyzed by fixed effect model and random effect model.
  
  
  RESULTS
  Thirteen reseaches on 2 219 patients were included in this study, 2 of which were randomly controlled studies. There were no significant differences in the postoperative complications (OR=1.00, 95%CI: 0.44-2.28,P>0.05) and mortality (OR=1.25, 95%CI: 0.62-2.48,P>0.05) between the PG group and the TG group, while there was significant difference in the 5-year survival rate (HR=0.87, 95%CI: 0.76-0.99,P=0.04). The 5-year survival rate in the TG group was higher than that in the PG group.
  
  
  CONCLUSIONS
  Total gastrectomy for the treatment of cancer of cardia and fundus has better long-term therapetic effect.
authors: Department of Gastrointestinal Surgery, Xiangya Hospital, Central South University, Changsha 410008, China.
authors: Jie
authors: J
authors: Ding
authors: Guoqing
authors: G
authors: Liao
authors: Zhongshu
authors: Z
authors: Yan
authors: Heli
authors: H
authors: Liu
authors: Jing
authors: J
authors: Tang
authors: Sheng
authors: S
authors: Liu
authors: Zhenqian
authors: Z
authors: Liu
authors: Jiancai
authors: J
authors: Wang
authors: Shunli
authors: S
authors: Yan
authors: Yi
authors: Y
authors: Zhou
mesh_terms: D002299:Cardia / Q000473:pathology; D005743:Gastrectomy / Q000379:methods*; D005748:Gastric Fundus / Q000473:pathology; D006801:Humans; D011379:Prognosis; D013274:Stomach Neoplasms / Q000401:mortality / Q000601:surgery*; D015996:Survival Rate