title: Basal cell carcinoma arising in association with a maxillary keratocyst in a patient with Gorlin-Goltz syndrome. Report of a case.
abstract: BACKGROUND
  Gorlin-Goltz syndrome, also known as nevoid basal cell carcinoma syndrome, is an autosomal dominant inherited disorder which is characterized by the presence of multiple basal cell carcinomas, maxillary keratocysts, and musculoskeletal anomalies.
  
  
  METHODS
  We present a case of a patient suffering from Gorlin-Goltz syndrome who developed an intraosseous basal cell carcinoma associated with a recurrent maxillary keratocyst. To our knowledge, this is the first case of malignant transformation of a keratocyst into a basal cell carcinoma described in the literature.
  
  
  CONCLUSIONS
  This case highlights the importance of careful histologic examination of keratocysts excised in patients suffering from Gorlin-Goltz syndrome.
authors: Department of Oral and Maxillofacial Surgery, G. Papanikolaou Hospital, Exohi, Thessaloniki, Ioanni Hatzoudi 9, Neapoli, 56727 Thessaloniki, Greece. lazaridoudm@yahoo.gr
authors: Maria Nikolaou
authors: MN
authors: Lazaridou
authors: Ioannis
authors: I
authors: Dimitrakopoulos
authors: Ioannis
authors: I
authors: Tilaveridis
authors: Christos
authors: C
authors: Iliopoulos
authors: Antigoni
authors: A
authors: Heva
mesh_terms: D000328:Adult; D001478:Basal Cell Nevus Syndrome / Q000235:genetics / Q000473:pathology*; D002280:Basal Cell Carcinoma / Q000235:genetics / Q000473:pathology*; D002471:Cell Transformation, Neoplastic / Q000235:genetics / Q000473:pathology*; D002869:Chromosome Aberrations; D018450:Disease Progression; D005500:Follow-Up Studies; D005799:Genes, Dominant / Q000235:genetics; D006801:Humans; D008297:Male; D008437:Maxilla / Q000473:pathology / Q000601:surgery; D008439:Maxillary Diseases / Q000235:genetics / Q000473:pathology*; D008441:Maxillary Neoplasms / Q000235:genetics / Q000473:pathology*; D008938:Mitosis / Q000502:physiology; D009807:Odontogenic Cysts / Q000235:genetics / Q000473:pathology*; D011862:Radiography, Panoramic; D012086:Reoperation