title: Timing is everything, even for cholinergic control.
abstract: Synaptic plasticity is widely considered to be a cellular mechanism underlying learning and memory. In this issue of Neuron, Gu and Yakel show that the precise timing of a single cholinergic pulse of activity can determine whether plasticity will occur at a glutamatergic synapse and confer long-term potentiation versus depression.
authors: Division of Biological Sciences, University of California, San Diego, La Jolla, CA 92093-0357, USA. dberg@ucsd.edu
authors: Darwin K
authors: DK
authors: Berg