title: Reengineering translational science: the time is right.
abstract: Despite dramatic advances in the molecular pathogenesis of disease, translation of basic biomedical research into safe and effective clinical applications remains a slow, expensive, and failure-prone endeavor. To pursue opportunities for disruptive translational innovation, the U.S. National Institutes of Health (NIH) intends to establish a new entity, the National Center for Advancing Translational Sciences (NCATS). The mission of NCATS is to catalyze the generation of innovative methods and technologies that will enhance the development, testing, and implementation of diagnostics and therapeutics across a wide range of diseases and conditions. The new center's activities will complement, and not compete with, translational research being carried out at NIH and elsewhere in the public and private sectors.
authors: Office of the Director, National Institutes of Health, Bethesda, MD 20892-8004, USA. francis.collins@nih.gov
authors: Francis S
authors: FS
authors: Collins
mesh_terms: D035843:Biomedical Research; D002986:Clinical Trials as Topic; D004059:Diffusion of Innovation; D055106:Genome-Wide Association Study; D006801:Humans; D009316:National Institutes of Health (U.S.); D057170:Translational Research, Biomedical; D014481:United States