title: Gastric cancer location and histological subtype in Pacific people and Māori defies international trends.
abstract: OBJECTIVE
  Gastric cancer location and histopathology in Pacific people (mostly of Samoan, Tongan, Niuean, or Cook Islands origin) and Māori in New Zealand has not been specifically examined.
  
  
  METHODS
  A retrospective review of all histologically-proven new cases of gastric adenocarcinoma and gastro-oesophageal adenocarcinoma at Middlemore Hospital (Auckland, New Zealand) from June 2003-June 2009 was conducted. Demographic data, clinical presentation, diagnostic/ staging investigations and surgical outcomes were recorded.
  
  
  RESULTS
  There were 133 patients of whom 79 (59%) were male. Forty-nine (37%) patients were of Pacific ethnicity and 34 (26%) were Māori. Māori (59.3 years; p=0.01) and Pacific (64.5 years; p=0.01) patients were significantly younger at diagnosis compared to European patients (77.2 years). European patients had more proximal tumours (n=18; 47%) compared to Pacific (n=5; 10%) and Māori (n=4; 12%) patients (p= 0.01). Pacific (n=25; 51%) and Māori (n=21; 62%) patients had a significantly higher percentage of diffuse-type gastric cancer compared to European (n=7; 18%) patients. There was no difference in stage of presentation between ethnic groups.
  
  
  CONCLUSIONS
  Māori and Pacific patients present with gastric cancer at higher rates and at a younger age. They have a predominance of diffuse-type antral and gastric body cancers which stand in contrast to global trends in gastric cancer.
authors: Department of Surgery, Middlemore Hospital, Auckland, New Zealand.
authors: Magdalena
authors: M
authors: Biggar
authors: Sanket
authors: S
authors: Srinivasa
authors: Binula
authors: B
authors: Wickramarachchi
authors: Richard
authors: R
authors: Babor
authors: Garth H
authors: GH
authors: Poole
authors: Andrew G
authors: AG
authors: Hill
mesh_terms: D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D000230:Adenocarcinoma / Q000175:diagnosis / Q000208:ethnology; D017677:Age Distribution; D002423:Cause of Death / Q000639:trends; D016099:Endoscopy, Gastrointestinal / Q000379:methods; D005500:Follow-Up Studies; D009017:Morbidity / Q000639:trends; D009367:Neoplasm Staging / Q000379:methods; D009520:New Zealand / Q000453:epidemiology; D011379:Prognosis; D012189:Retrospective Studies; D017678:Sex Distribution; D013274:Stomach Neoplasms / Q000175:diagnosis / Q000208:ethnology; D000095188:Pacific Island People; D000095284:Maori People