title: Florid cutaneous papillomatosis and acanthosis nigricans maligna revealing gastric adenocarcinoma.
abstract: This paper reports the case of a 57-year-old, previously healthy male with no systemic symptoms who over a short period of time developed multiple wart-like lesions on his trunk, limbs and face, typical lesions of acanthosis nigricans in the major body folds and tripe palms. Diagnostic tests revealed a metastatic gastric adenocarcinoma. Despite the implementation of therapy, which had a transient effect on the tumor and skin lesions, the patient died in 14 months. The association of these three paraneoplastic dermatoses (florid cutaneous papillomatosis, acanthosis nigricans maligna and tripe palms) in the same patient, apparently with a common pathogenic mechanism, is noteworthy.
authors: Teaching Hospitals of the University of Coimbra; EPE Service of Dermatology, Coimbra, Portugal. anabrinca@gmail.com
authors: Ana
authors: A
authors: Brinca
authors: José Carlos
authors: JC
authors: Cardoso
authors: Maria Manuel
authors: MM
authors: Brites
authors: Oscar
authors: O
authors: Tellechea
authors: Américo
authors: A
authors: Figueiredo
mesh_terms: D000052:Acanthosis Nigricans / Q000150:complications* / Q000473:pathology; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D008875:Middle Aged; D010212:Papilloma / Q000150:complications* / Q000473:pathology; D012878:Skin Neoplasms / Q000150:complications* / Q000473:pathology; D013274:Stomach Neoplasms / Q000150:complications* / Q000473:pathology