title: [Application of BODIPY-trimethylmelamine conjugate for DNA cross-linking in vitro].
abstract: Conjugate the fluorescent dye 4,4-difluoro-1,3,5,7-tetramethyl-4-bora-3a,4a-diaza-s-indatsen-8-propionic acid (BODIPY) and N2,N4,N6-trimethylmelamine was obtained. It was shown that this compound in the presence of formaldehyde generates covalent cross-links of DNA strands in vitro.
authors: V A
authors: VA
authors: Efimov
authors: S V
authors: SV
authors: Fediunin
authors: O G
authors: OG
authors: Chakhmakhcheva
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000138:chemical synthesis* / Q000627:therapeutic use; D001896:Boron Compounds / Q000138:chemical synthesis*; D003432:Cross-Linking Reagents / Q000138:chemical synthesis*; D004247:DNA / Q000737:chemistry; D005456:Fluorescent Dyes / Q000138:chemical synthesis*; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy; D013050:Spectrometry, Fluorescence; D014227:Triazines / Q000138:chemical synthesis*
chemical_list: C095489:4,4-difluoro-4-bora-3a,4a-diaza-s-indacene; D000970:Antineoplastic Agents; D001896:Boron Compounds; D003432:Cross-Linking Reagents; D005456:Fluorescent Dyes; D014227:Triazines; C049507:trimelamol; D004247:DNA