title: Clinical evaluation of a PHMB-impregnated biocellulose dressing on paediatric lacerations.
abstract: OBJECTIVE
  To evaluate the clinical benefits, primarily tolerability and reduction in pain levels, associated with the use of a PHMB-impregnated biosynthetic cellulose dressing (Suprasorb X + PHMB) on paediatric heel lacerations.
  
  
  METHODS
  These lacerations were caused when children, who were being transported on their parents' bicycles, got their heels trapped in the wheel spokes. Where these injuries just comprised skin contusion and laceration, treatment had previously comprised cleansing followed by application of conventional dressings and moist wound healing dressings. However, the high incidence of infection necessitated regular dressing changes, which caused parents and children stress and anxiety. This clinical evaluation assessed the benefits of a new treatment protocol, where the PHMB-impregnated biocellulose dressing was applied and left in situ until epithelialisation occurred. A cork splint was used for 3 days to prevent pes equinus and to let the ankle joint rest. Change in wound size (cm²), incidence of local infection, wound bed characteristics and pain levels (measured on a 0-10 paediatric pain scale) were assessed at 3-day intervals during the 14-day treatment period. Satisfaction with the dressing was also evaluated.
  
  
  RESULTS
  Twenty children (mean age 5.6 years (± 1.33) were recruited into the study and included in the analysis. The mean baseline wound area was 8.60cm² (± 6.57). The mean time to complete wound closure was 12.95 days (± 7.69) with a mean total of 4.70 visits (± 1.56). The mean VAS pain score was 9.55 (± 0.69), compared with 0.15 (± 0.37) on day 14 (p<0.003). At the second visit (after 3 days) 17 of the 20 children were reported to be free of pain. No cases of local infection were noted.
  
  
  CONCLUSIONS
  The dressing was found to be child and parent friendly. The evaluation also showed that it was well tolerated and achieved good healing outcome. It has now been incorporated into the clinic's treatment protocol for these wounds.
  
  
  BACKGROUND
  None. The authors have no relevant financial interest in this article. All authors were involved in the critical revision of the manuscript for important intellectual content.
authors: Emergency Department and Wound Healing Centre, Bovenlj Hospital, Amsterdam, The Natherlands.
authors: G
authors: G
authors: Elzinga
authors: J
authors: J
authors: van Doorn
authors: A M
authors: AM
authors: Wiersema
authors: R J
authors: RJ
authors: Klicks
authors: A
authors: A
authors: Andriessen
authors: J G
authors: JG
authors: Alblas
authors: H
authors: H
authors: Spits
authors: A
authors: A
authors: Post
authors: M
authors: M
authors: van Gent
mesh_terms: D001458:Bandages; D001642:Bicycling / Q000293:injuries*; D001645:Biguanides / Q000627:therapeutic use*; D001672:Biocompatible Materials; D002482:Cellulose; D002648:Child; D002675:Child, Preschool; D004202:Disinfectants / Q000627:therapeutic use*; D005260:Female; D018409:Foot Injuries / Q000628:therapy*; D006365:Heel; D006801:Humans; D022125:Lacerations / Q000628:therapy*; D008297:Male; D009426:Netherlands; D014945:Wound Healing
chemical_list: D001645:Biguanides; D001672:Biocompatible Materials; D004202:Disinfectants; C031233:polihexanide; D002482:Cellulose