title: Rhodamine-based derivatives for Cu2+ sensing: spectroscopic studies, structure-recognition relationships and its test strips.
abstract: A rhodamine spirolactam/2-hydrazinopyridine derivative was synthesized and characterized, which exhibited high selectivity to Cu(2+) over other metal cations. The Cu(2+) recognition of this rhodamine derivative could be detected by fluorescence spectra, absorption spectra and an obvious color change which was observed easily by naked-eyes. The binding of this rhodamine derivative to Cu(2+) is instantaneous and sensitive. Moreover, a linear relationship was found between the fluorescence intensity at 575 nm from 0.5×10(-6) M to 3.0×10(-6) M of Cu(2+) concentration, and the limit of detection (LOD) was at low concentration of 2.11×10(-8) M, this would benefit for the establishment of standard working curves in practical Cu(2+) detection. Additionally, we synthesized rhodamine spirolactam/2-aminomethylpyridine derivative and rhodamine spirolactam/phenylhydrazine derivative as analogs for elucidate the structure-recognition relationships. Finally, we prepared the test strips of rhodamine spirolactam/2-hydrazinopyridine derivative for practical chromogenic the Cu(2+) detection.
authors: Department of Chemistry and Chemical Engineering, University of Science and Technology Beijing, 100083, China. yxyang63@yahoo.com.cn
authors: Yunxu
authors: Y
authors: Yang
authors: Weiling
authors: W
authors: Gao
authors: Ruilong
authors: R
authors: Sheng
authors: Weili
authors: W
authors: Wang
authors: Hui
authors: H
authors: Liu
authors: Wumin
authors: W
authors: Yang
authors: Tianyi
authors: T
authors: Zhang
authors: Xuetao
authors: X
authors: Zhang
mesh_terms: D001665:Binding Sites; D015374:Biosensing Techniques / Q000379:methods*; D002863:Chromogenic Compounds / Q000032:analysis / Q000737:chemistry; D003300:Copper / Q000032:analysis*; D005456:Fluorescent Dyes / Q000737:chemistry; D008954:Models, Biological; D011934:Reagent Strips / Q000737:chemistry / Q000494:pharmacology; D012235:Rhodamines / Q000737:chemistry*; D013057:Spectrum Analysis / Q000379:methods*; D013329:Structure-Activity Relationship; D014867:Water / Q000737:chemistry
chemical_list: D002863:Chromogenic Compounds; D005456:Fluorescent Dyes; D011934:Reagent Strips; D012235:Rhodamines; D014867:Water; D003300:Copper