title: The complete genome sequence of an enterovirus 76 isolate in China reveals a recombination event.
abstract: Enterovirus 76 (EV76) is a new member of species Human Enterovirus A (HEV-A). So far, the only complete genome sequence of the prototype strain from France has been available. In this study, we determined the complete nucleotide sequence of strain 04360, isolated from an acute flaccid paralysis patient in Shandong province, China in 2004. Sequence analysis revealed 80.7-94.7% VP1 nucleotide identity to other EV76 strains and provided evidence of recombination with other types of HEV-A in the P2 and P3 coding regions.
authors.affiliation: Department of Epidemiology, School of Public Health, Shandong University, No. 44 Wenhuaxi Road, Jinan 250012, People's Republic of China.
authors.forename: Aiqiang
authors.initials: A
authors.lastname: Xu
authors.forename: Zexin
authors.initials: Z
authors.lastname: Tao
authors.forename: Xiaojuan
authors.initials: X
authors.lastname: Lin
authors.forename: Yao
authors.initials: Y
authors.lastname: Liu
authors.forename: Yong
authors.initials: Y
authors.lastname: Zhang
authors.forename: Lizhi
authors.initials: L
authors.lastname: Song
authors.forename: Haiyan
authors.initials: H
authors.lastname: Wang
authors.forename: Jing
authors.initials: J
authors.lastname: Yang
authors.forename: Yan
authors.initials: Y
authors.lastname: Li
authors.forename: Feng
authors.initials: F
authors.lastname: Ji
authors.forename: Lei
authors.initials: L
authors.lastname: Feng
authors.forename: Zhongtang
authors.initials: Z
authors.lastname: Zhao
mesh_terms: D001483:Base Sequence; D002681:China / Q000453:epidemiology; D004770:Enterovirus / Q000235:genetics*; D004769:Enterovirus Infections / Q000453:epidemiology / Q000821:virology*; D016679:Genome, Viral; D006801:Humans; D008969:Molecular Sequence Data; D010802:Phylogeny; D016865:Reassortant Viruses / Q000235:genetics*