title: Outcome predictors in treatment of yaws.
abstract: To estimate failure rates after treatment with benzathine penicillin and to identify determinants of failure that affected outcomes for yaws, we conducted a cohort study of 138 patients; treatment failed in 24 (17.4%). Having low initial titers on Venereal Disease Research Laboratory test and living in a village where yaws baseline incidence was high were associated with increased likelihood of treatment failure.
authors.affiliation: Lihir Medical Centre, Lihir Island, Papua New Guinea. oriolmitja@hotmail.com
authors.forename: Oriol
authors.initials: O
authors.lastname: Mitjà
authors.forename: Russell
authors.initials: R
authors.lastname: Hays
authors.forename: Anthony
authors.initials: A
authors.lastname: Ipai
authors.forename: David
authors.initials: D
authors.lastname: Gubaila
authors.forename: Francis
authors.initials: F
authors.lastname: Lelngei
authors.forename: Martin
authors.initials: M
authors.lastname: Kirara
authors.forename: Raymond
authors.initials: R
authors.lastname: Paru
authors.forename: Quique
authors.initials: Q
authors.lastname: Bassat
mesh_terms: D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D005260:Female; D006801:Humans; D008297:Male; D010401:Penicillin G Benzathine / Q000627:therapeutic use*; D011379:Prognosis; D012883:Skin Ulcer / Q000188:drug therapy / Q000473:pathology; D017211:Treatment Failure; D016896:Treatment Outcome; D015001:Yaws / Q000175:diagnosis* / Q000188:drug therapy* / Q000453:epidemiology / Q000473:pathology
chemical_list: D000900:Anti-Bacterial Agents; D010401:Penicillin G Benzathine