title: Update on childhood and adolescent immunizations: selected review of US recommendations and literature: part 1.
abstract: OBJECTIVE
  To provide a clinically relevant synopsis of research findings regarding childhood and adolescent vaccines.
  
  
  RESULTS
  Much research confirms the safety, immunogenicity, and efficacy of specific vaccines as well as the positive impact on overall morbidity and mortality. Prevention and control strategies involve the expansion of vaccine recommendations to include more individuals and/or more vaccine doses. In addition, the role of universal infant vaccination, the advantages of even partial immunization, and the documented benefits of recently introduced vaccines are explored. The material in this review includes important areas of clinical practice improvement, such as awareness of interim recommendations or monitoring of vaccine failures. Literature on hepatitis B, rotavirus, Haemophilus influenzae type b conjugate, and pneumococcal vaccines is included in this first of two articles.
  
  
  CONCLUSIONS
  New research on childhood and adolescent vaccines is anticipated to shape the practice of pediatric providers. Research will continue to provide the science to optimize protection and to promote the health and well being of all children and adolescents.
authors.affiliation: Department of Pediatrics, Children's Hospital at Dartmouth, Lebanon, New Hampshire, USA.
authors.forename: Kathryn E
authors.initials: KE
authors.lastname: Fay
authors.forename: Joanne
authors.initials: J
authors.lastname: Lai
authors.forename: Joseph A
authors.initials: JA
authors.lastname: Bocchini
mesh_terms: D000293:Adolescent; D001428:Bacterial Vaccines / Q000008:administration & dosage; D002648:Child; D006192:Haemophilus Infections / Q000517:prevention & control; D019741:Haemophilus influenzae type b; D006509:Hepatitis B / Q000517:prevention & control; D006801:Humans; D007115:Immunization Schedule; D011008:Pneumococcal Infections / Q000517:prevention & control; D012400:Rotavirus Infections / Q000517:prevention & control; D014481:United States; D014611:Vaccination / Q000009:adverse effects / Q000379:methods / Q000706:statistics & numerical data; D014765:Viral Vaccines / Q000008:administration & dosage
chemical_list: D001428:Bacterial Vaccines; D014765:Viral Vaccines