title: Photodimerisation of glycothymidines in solution and in micelles.
abstract: Glycothymidines were designed and synthesized as a new class of functional glycomimetics in which a photochemical [2+2] cycloaddition of the thymine moiety induces structural changes of carbohydrate presentation. To test if photodimerisation of these glycothymidines is feasible within an array of molecules, the photochemical reaction was investigated using NMR and NMR diffusion experiments in solution as well as in the supramolecular context of detergent micelles that mimic cellular membranes.
authors.affiliation: Otto Diels Institute of Organic Chemistry, Christiana Albertina University of Kiel, Otto-Hahn-Platz 3-4, D-24098 Kiel, Germany.
authors.forename: Kirsten
authors.initials: K
authors.lastname: Schwekendiek
authors.forename: Hauke
authors.initials: H
authors.lastname: Kobarg
authors.forename: Lena
authors.initials: L
authors.lastname: Daumlechner
authors.forename: Frank D
authors.initials: FD
authors.lastname: Sönnichsen
authors.forename: Thisbe K
authors.initials: TK
authors.lastname: Lindhorst
mesh_terms: D019281:Dimerization; D006027:Glycosides / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D008823:Micelles; D055668:Photochemical Processes; D012996:Solutions / Q000737:chemistry; D013936:Thymidine / Q000737:chemistry*
chemical_list: D006027:Glycosides; D008823:Micelles; D012996:Solutions; D013936:Thymidine