title: Efficacy of antimicrobial triclosan-coated polyglactin 910 (Vicryl* Plus) suture for closure of the abdominal wall after colorectal surgery.
abstract: This study compared Triclosan coated polyglactin 910 (Vicryl* Plus) with polyglactin 910 (Vicryl*) on abdominal wall healing in colorectal surgery patients. 184 patients with colorectal cancer were included in the study. In 91, the abdominal wall was closed with the Vicryl* Plus, and in 93 patients with Vicryl*. Demographic characteristics, biochemical inflammatory parameters, wound appearance, length of hospital stay, postoperative wound complications and post-incisional hernia were recorded. In the Vicryl* Plus group there was a shorter hospital stay (13.2 +/- 1.3 days; 21.4 +/- 2.8 respectively). In the Vicryl* Plus group inflammatory parameters decreased to normal within the first week whereas in the Vicryl* group remained increased. In the Vicryl* Plus group four patients had a wound discharge, seven had inflammatory reactions to the skin sutures. One dehiscence was noticed. In the Vicryl* group 12 patients had an SSI, 14 patients had inflammatory reactions to the skin sutures and 7 patients had a wound dehiscence. Closure of the abdominal wall using Vicryl* Plus decreases postoperative wound complications, length of hospital stay and is associated with a more rapid return of inflammatory markers to normal.
authors.affiliation: University of Zagreb, "Sveti Duh" University Hospital, University Department of Surgery, Zagreb, Croatia.
authors.forename: Zarko
authors.initials: Z
authors.lastname: Rasić
authors.forename: Dragan
authors.initials: D
authors.lastname: Schwarz
authors.forename: Visnja Nesek
authors.initials: VN
authors.lastname: Adam
authors.forename: Marko
authors.initials: M
authors.lastname: Sever
authors.forename: Nermin
authors.initials: N
authors.lastname: Lojo
authors.forename: Domagoj
authors.initials: D
authors.lastname: Rasić
authors.forename: Tomislav
authors.initials: T
authors.lastname: Matejić
mesh_terms: D034861:Abdominal Wall / Q000601:surgery; D058107:Abdominal Wound Closure Techniques / Q000295:instrumentation*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000891:Anti-Infective Agents, Local; D015179:Colorectal Neoplasms / Q000601:surgery*; D016503:Drug Delivery Systems / Q000295:instrumentation; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011098:Polyglactin 910; D013530:Surgical Wound Infection / Q000517:prevention & control; D013537:Sutures; D014260:Triclosan
chemical_list: D000891:Anti-Infective Agents, Local; D011098:Polyglactin 910; D014260:Triclosan