title: [Relationship between fractional esterification rate of high density lipoprotein cholesterol and coronary artery disease].
abstract: OBJECTIVE
  To assess the relationship between fractional esterification rate of high density lipoprotein cholesterol (FER(HDL)) and coronary artery disease.
  
  
  METHODS
  A total of 131 hospitalized patients underwent coronary angiography due to chest pain were included in the study and patients were divided into CAD group (n = 76) and non CAD group (n = 55) according to coronary angiogram. Clinical and laboratory data including biochemical laboratory, FER(HDL) and lipid subclasses were analyzed.
  
  
  RESULTS
  The FER(HDL) value of CAD group was significantly higher than that of the non CAD group (21.70 ± 8.73 vs. 18.65 ± 6.26, P < 0.05). There was an increased trend of FER(HDL) with numbers of diseased coronary arteries, significant difference was evidenced between non CAD group and 3-vessel group (18.65 ± 6.26 vs. 24.00 ± 9.22, P < 0.05). FER(HDL) was positively correlated with TG (r = 0.647, P < 0.001), LDLb-C(r = 0.441, P < 0.001) and negatively correlated with HDL-C (r = -0.708, P < 0.001) and HDL(2)-C (r = -0.748, P < 0.001).
  
  
  CONCLUSIONS
  Our data showed that the values of FER(HDL) were significantly increased in CAD patients and correlated with the severity of the CAD.
authors.affiliation: Department of Cardiology, Beijing Hospital, Beijing 100730, China.
authors.forename: Wen
authors.initials: W
authors.lastname: Mao
authors.forename: Jun
authors.initials: J
authors.lastname: Dong
authors.forename: Hong-xia
authors.initials: HX
authors.lastname: Li
authors.forename: Min
authors.initials: M
authors.lastname: Zhou
authors.forename: Han-bang
authors.initials: HB
authors.lastname: Guo
authors.forename: Shu
authors.initials: S
authors.lastname: Wang
authors.forename: Wen-xiang
authors.initials: WX
authors.lastname: Chen
authors.forename: Qing
authors.initials: Q
authors.lastname: He
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D008076:Cholesterol, HDL / Q000378:metabolism*; D008078:Cholesterol, LDL / Q000378:metabolism; D017023:Coronary Angiography; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging / Q000378:metabolism*; D004951:Esterification; D005260:Female; D006801:Humans; D008075:Lipoproteins, HDL / Q000378:metabolism; D008077:Lipoproteins, LDL / Q000378:metabolism; D008297:Male; D008875:Middle Aged
chemical_list: D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D008075:Lipoproteins, HDL; D008077:Lipoproteins, LDL