title: MRI-guided ablation of breast cancer: where do we stand today?
abstract: The treatment of patients with localized breast cancer has changed considerably over the past few decades. The next challenge is to use image-guided minimally invasive tumor ablation techniques. The fact that MRI is the most accurate imaging modality for visualization and delineation of breast tumor margins in three dimensions and provides MRI-based temperature mapping, makes it particularly applicable for monitoring during minimally invasive ablation techniques. The overall result of the studies performed on MRI-guided minimally invasive tumor ablation studies are varying, with reported total tumor ablation rates ranging between 20% and 100%. Strict selection of patients, consensus on the treatment zone margin and optimization of MR-imaging, should make MRI-guided breast cancer tumor ablation a useful tool in clinical practice.
authors.affiliation: Department of Surgery, University Medical Center Utrecht, The Netherlands.
authors.forename: Emily L
authors.initials: EL
authors.lastname: Postma
authors.forename: Richard
authors.initials: R
authors.lastname: van Hillegersberg
authors.forename: Bruce L
authors.initials: BL
authors.lastname: Daniel
authors.forename: Laura G
authors.initials: LG
authors.lastname: Merckel
authors.forename: Helena M
authors.initials: HM
authors.lastname: Verkooijen
authors.forename: Maurice A A J
authors.initials: MA
authors.lastname: van den Bosch
mesh_terms: D001940:Breast / Q000473:pathology; D001943:Breast Neoplasms / Q000532:radiotherapy* / Q000628:therapy*; D017115:Catheter Ablation / Q000379:methods; D004867:Equipment Design; D005260:Female; D006801:Humans; D006979:Hyperthermia, Induced / Q000379:methods; D007834:Lasers; D008279:Magnetic Resonance Imaging / Q000379:methods*; D053783:Magnetic Resonance Imaging, Interventional / Q000379:methods*; D019060:Minimally Invasive Surgical Procedures / Q000379:methods; D013696:Temperature