title: Pseudomonas aeruginosa endophthalmitis after penetrating keratoplasty transmitted from the same donor to two recipients confirmed by pulsed-field gel electrophoresis.
abstract: Two devastating cases of multidrug-resistant Pseudomonas aeruginosa endophthalmitis after keratoplasty as the result of transmission from the same donor were confirmed by pulsed-field gel electrophoresis. Strategies for preventing donor-to-host transmission, such as the use of antimicrobial agents of greater efficacy and better methods for detecting microorganisms in preservation medium, could minimize this type of transmission.
authors.affiliation: Department of Ophthalmology, Universidade Estadual de Londrina, Robert Kock, 60, 86010 100, Londrina, Parana, Brazil. aoguido@gmail.com
authors.forename: Ana Paula Miyagusko Taba
authors.initials: AP
authors.lastname: Oguido
authors.forename: Antonio Marcelo Barbante
authors.initials: AM
authors.lastname: Casella
authors.forename: Ana Luisa
authors.initials: AL
authors.lastname: Hofling-Lima
authors.forename: Sergio Arruda
authors.initials: SA
authors.lastname: Pacheco
authors.forename: Paulo José Martins
authors.initials: PJ
authors.lastname: Bispo
authors.forename: Fernanda
authors.initials: F
authors.lastname: Marques
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D018562:Disease Transmission, Infectious; D024901:Drug Resistance, Multiple, Bacterial; D016521:Electrophoresis, Gel, Pulsed-Field; D009877:Endophthalmitis / Q000175:diagnosis / Q000382:microbiology*; D006801:Humans; D015948:Keratoplasty, Penetrating / Q000009:adverse effects*; D008297:Male; D058889:Molecular Typing; D011552:Pseudomonas Infections / Q000175:diagnosis* / Q000382:microbiology / Q000635:transmission; D011550:Pseudomonas aeruginosa / Q000145:classification / Q000187:drug effects / Q000235:genetics / Q000302:isolation & purification*; D013530:Surgical Wound Infection / Q000175:diagnosis / Q000382:microbiology*; D014019:Tissue Donors
chemical_list: D000900:Anti-Bacterial Agents