title: Defects in coagulation encountered in small animal critical care.
abstract: Critically ill small animals are at risk for developing coagulation abnormalities. The processes of inflammation and coagulation are intertwined, and severe inflammation can lead to disturbances of coagulation. Severe coagulation dysfunction is associated with increased morbidity and mortality. Pathophysiology, diagnosis, and treatment of coagulation dysfunction are discussed. Defects in coagulation in small animal patients are complex and a consensus on diagnosis and treatment has yet to be reached.
authors.affiliation: Department of Small Animal Medicine and Surgery, University of Georgia, 501 D.W. Brooks Drive, Athens, GA 30602, USA. brainard@uga.edu
authors.forename: Benjamin M
authors.initials: BM
authors.lastname: Brainard
authors.forename: Andrew J
authors.initials: AJ
authors.lastname: Brown
mesh_terms: D000818:Animals; D000925:Anticoagulants / Q000627:therapeutic use; D002371:Cat Diseases / Q000175:diagnosis / Q000503:physiopathology* / Q000628:therapy; D002415:Cats; D003422:Critical Care; D016638:Critical Illness / Q000628:therapy; D019468:Disease Management; D004211:Disseminated Intravascular Coagulation / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy / Q000662:veterinary*; D004283:Dog Diseases / Q000175:diagnosis / Q000503:physiopathology* / Q000628:therapy; D004285:Dogs; D006801:Humans; D018805:Sepsis / Q000150:complications / Q000503:physiopathology / Q000628:therapy / Q000662:veterinary; D013045:Species Specificity; D018746:Systemic Inflammatory Response Syndrome / Q000150:complications / Q000503:physiopathology / Q000628:therapy / Q000662:veterinary
chemical_list: D000925:Anticoagulants