title: Determination of the mechanical properties of the skin of pig foetuses with respect to its structure.
abstract: Skin is an important barrier protecting the organism against external environmental factors. Determination of its mechanical characteristics as regards its structure has significant scientific and application value. In this work, uniaxial tensile tests were conducted to determine the basic mechanical parameters of skin with respect to its structure. The subject of the study were skin samples taken from domestic pig foetuses. They were excised from different parts of body, in the direction parallel to the long axis of the body. Regardless of the sampling site, the tests revealed no significant differences in the values of the maximum tensile strength (2.08 ± 0.25 MPa) and the conventional Young's modulus (5.87 ± 1.52 MPa). The mechanical and structural tests confirmed that regardless of the sampling region the skin of domestic pig foetuses may constitute a human skin substitute model.
authors.affiliation: Division of Biomedical Engineering and Experimental Mechanics, Wrocław University of Technology, Poland.
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Zak
authors.forename: Piotr
authors.initials: P
authors.lastname: Kuropka
authors.forename: Magdalena
authors.initials: M
authors.lastname: Kobielarz
authors.forename: Agnieszka
authors.initials: A
authors.lastname: Dudek
authors.forename: Katarzyna
authors.initials: K
authors.lastname: Kaleta-Kuratewicz
authors.forename: Sylwia
authors.initials: S
authors.lastname: Szotek
mesh_terms: D000818:Animals; D001696:Biomechanical Phenomena / Q000502:physiology; D005333:Fetus / Q000033:anatomy & histology* / Q000502:physiology*; D024022:Fibrillar Collagens / Q000378:metabolism; D012867:Skin / Q000033:anatomy & histology*; D012879:Skin Physiological Phenomena; D013314:Stress, Mechanical; D034421:Sus scrofa / Q000502:physiology*
chemical_list: D024022:Fibrillar Collagens