title: Chorioretinal architecture in Aicardi syndrome: an optical coherence tomography and fluorescein angiography study.
abstract: Aicardi syndrome is a rare congenital disorder with a classic triad of infantile spasms, chorioretinal lacunae, and agenesis of the corpus callosum. We report the use of fluorescein angiography and spectral domain optical coherence tomography to examine the posterior segment structures in an 8-month-old girl with Aicardi syndrome. Most of the observed features correlated with previously published histopathological findings, but inner nuclear layer cysts have not been previously described. To our knowledge, this is the first study of the tomographic and angiographic chorioretinal features in vivo.
authors.affiliation: Department of Ophthalmology, University of California-San Francisco, San Francisco, California 94143-0412, USA.
authors.forename: Joseph N
authors.initials: JN
authors.lastname: Martel
authors.forename: Tina
authors.initials: T
authors.lastname: Rutar
authors.forename: Brandon J
authors.initials: BJ
authors.lastname: Lujan
authors.forename: Alejandra
authors.initials: A
authors.lastname: de Alba Campomanes
mesh_terms: D058540:Aicardi Syndrome / Q000175:diagnosis*; D015862:Choroid Diseases / Q000175:diagnosis*; D003103:Coloboma / Q000175:diagnosis; D003560:Cysts / Q000175:diagnosis; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D007223:Infant; D009898:Optic Disk / Q000002:abnormalities; D012164:Retinal Diseases / Q000175:diagnosis*; D041623:Tomography, Optical Coherence