title: Genome cartography: charting the apicomplexan genome.
abstract: Genes reside in particular genomic contexts that can be mapped at many levels. Historically, 'genetic maps' were used primarily to locate genes. Recent technological advances in the determination of genome sequences have made the analysis and comparison of whole genomes possible and increasingly tractable. What do we see if we shift our focus from gene content (the 'inventory' of genes contained within a genome) to the composition and organization of a genome? This review examines what has been learned about the evolution of the apicomplexan genome as well as the significance and impact of genomic location on our understanding of the eukaryotic genome and parasite biology.
authors.affiliation: Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, USA. jkissing@uga.edu
authors.forename: Jessica C
authors.initials: JC
authors.lastname: Kissinger
authors.forename: Jeremy
authors.initials: J
authors.lastname: DeBarry
mesh_terms: D016782:Apicomplexa / Q000235:genetics*; D002503:Centromere / Q000235:genetics; D002843:Chromatin / Q000235:genetics*; D002874:Chromosome Mapping; D019143:Evolution, Molecular; D005786:Gene Expression Regulation; D022761:Gene Transfer, Horizontal; D017125:Genes, Protozoan; D016678:Genome; D008928:Mitochondria / Q000235:genetics; D026801:Synteny; D016615:Telomere
chemical_list: D002843:Chromatin