title: An innovative model for changing the lifestyles of persons with obesity and/or Type 2 diabetes mellitus.
abstract: OBJECTIVE
  To describe the multidisciplinary lifestyle intervention model used in an experimental CURIAMO (Centro Universitario Ricerca Interdipartimentale Attività Motoria) project designed to validate the short- and long-term efficacy of the model in obesity and Type 2 diabetes.
  
  
  METHODS
  Over a 3-yr period, about 1000 adults (70% diabetes-free and overweight or obese; 30% with Type 2 diabetes and overweight or obese).
  
  
  METHODS
  Age range 18-80 yr, body mass index >27 kg/m2 with or without Type 2 diabetes mellitus; participants will be divided into three age groups (18-45, 45-65, 65-80 yr). The study duration will be from 5 to 6 yr: 1 yr of intervention followed by a mean follow-up period of 4 yr. In the first years, after a 4- month intensive lifestyle intervention, subjects will follow a maintenance programme. The intervention, which includes seven steps, involves the following experts: endocrinologists, sport medicine doctors or cardiologists, psychologists, dietitians, educators, nurses, exercise physiologists, and promoters of outdoor activities.
  
  
  RESULTS
  The main endpoint of the study is to measure the efficacy of the lifestyle improvement intervention, defined as a loss of at least 7% of body weight combined with an increase of at least 10 MET/h-1·week-1 of energy expenditure by physical activity, after 1 yr and during the follow-up. A cost/utility analysis of the model will be made in participants with diabetes.
  
  
  CONCLUSIONS
  We expect that the CURIAMO model will be highly effective, and that the aim of the intervention will be achieved in more than 70% of cases.
authors.affiliation: Healthy Lifestyle Institute (C.U.R.I.A.MO.: Centro Universitario Ricerca Interdipartimentale Attività Motoria), University of Perugia, Via G. Bambagioni 19, 06126 Perugia, Italy. pierpaolodefeo@gmail.com
authors.forename: P
authors.initials: P
authors.lastname: De Feo
authors.forename: C
authors.initials: C
authors.lastname: Fatone
authors.forename: P
authors.initials: P
authors.lastname: Burani
authors.forename: N
authors.initials: N
authors.lastname: Piana
authors.forename: C
authors.initials: C
authors.lastname: Pazzagli
authors.forename: D
authors.initials: D
authors.lastname: Battistini
authors.forename: D
authors.initials: D
authors.lastname: Capezzali
authors.forename: R
authors.initials: R
authors.lastname: Pippi
authors.forename: B
authors.initials: B
authors.lastname: Chipi
authors.forename: C
authors.initials: C
authors.lastname: Mazzeschi
mesh_terms: D000328:Adult; D003362:Cost-Benefit Analysis; D003924:Diabetes Mellitus, Type 2 / Q000628:therapy*; D037001:Directive Counseling; D015444:Exercise; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007558:Italy; D008019:Life Style; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000628:therapy*; D010348:Patient Care Team; D015431:Weight Loss