title: Comparison of hemoglobin A1c with fasting plasma glucose and 2-h postchallenge glucose for risk stratification among women with recent gestational diabetes mellitus.
abstract: OBJECTIVE
  Postpartum testing with a 75-g 2-h oral glucose tolerance test or fasting plasma glucose (FPG) alone is often not performed among women with histories of gestational diabetes mellitus (GDM). Use of hemoglobin A(1c) (A1C) might increase testing. The association between A1C and glucose has not been examined in women with histories of GDM.
  
  
  METHODS
  We assessed the association of A1C ≥5.7% with FPG ≥100 mg/dL and 2-h glucose ≥140 mg/dL among 54 women with histories of GDM between 6 weeks and 36 months postpartum.
  
  
  RESULTS
  A1C ≥5.7% had 65% sensitivity and 68% specificity for identifying elevated FPG or 2-h glucose and 75% sensitivity and 62% specificity for elevated FPG alone. The area under the receiver operating characteristic curve for A1C was 0.76 for elevated FPG or 2-h glucose and 0.77 for elevated FPG alone.
  
  
  CONCLUSIONS
  The agreement between A1C and glucose levels is fair for detection of abnormal glucose tolerance among women with histories of GDM.
authors.affiliation: Department of Medicine and Obstetrics & Gynecology, University of Michigan, Ann Arbor, MI, USA. cathkim@umich.edu
authors.forename: Catherine
authors.initials: C
authors.lastname: Kim
authors.forename: William H
authors.initials: WH
authors.lastname: Herman
authors.forename: N Wah
authors.initials: NW
authors.lastname: Cheung
authors.forename: Erica P
authors.initials: EP
authors.lastname: Gunderson
authors.forename: Caroline
authors.initials: C
authors.lastname: Richardson
mesh_terms: D000328:Adult; D001786:Blood Glucose / Q000378:metabolism*; D015992:Body Mass Index; D016640:Diabetes, Gestational / Q000097:blood* / Q000378:metabolism*; D005260:Female; D006442:Glycated Hemoglobin / Q000378:metabolism*; D006801:Humans; D049590:Postpartum Period / Q000097:blood / Q000378:metabolism; D011247:Pregnancy
chemical_list: D001786:Blood Glucose; D006442:Glycated Hemoglobin