title: First report of human infection by Rhodoplanes sp., Alphaproteobacteria in China.
abstract: We isolated a novel strain of Alphaproteobacteria from a patient, who had medical history of chronic rhinitis for more than twenty years and recently experienced local skin abscess and ulcer. He eventually died of multiple organ failure due to multi-antibiotics resistance. We identified the microorganism by 16SrRNA sequencing and found that it belonged to the genus Rhodoplanes. It was named as Rhodoplanes sp. strain ZLJ-0. It is resumed that Rhodoplanes sp. strain ZLJ-0 might be an emerging human pathogen involving in unknown febrile conditions and could cause local infection of any tissues or organs. Differential diagnosis of febrile patients should be conducted in clinical practice and research on emerging pathogens of Alphaproteobacteria should be performed to determine the epidemiology, clinical symptoms and pathogenic features of these pathogens.
authors.affiliation: Department of Rickettsiology, National Institute of Communicable Disease Control and Prevention, China CDC, Changping, Beijng, People's Republic of China. zhanglijuan@icdc.cn
authors.forename: L J
authors.initials: LJ
authors.lastname: Zhang
authors.forename: G Q
authors.initials: GQ
authors.lastname: Wang
authors.forename: H L
authors.initials: HL
authors.lastname: Yu
authors.forename: J
authors.initials: J
authors.lastname: Wang
authors.forename: S W
authors.initials: SW
authors.lastname: Wang
authors.forename: Y
authors.initials: Y
authors.lastname: Jia
authors.forename: Y Y
authors.initials: YY
authors.lastname: Yu
authors.forename: J G
authors.initials: JG
authors.lastname: Xu
mesh_terms: D000038:Abscess / Q000175:diagnosis / Q000382:microbiology / Q000473:pathology; D001424:Bacterial Infections / Q000175:diagnosis* / Q000382:microbiology* / Q000473:pathology; D001853:Bone Marrow / Q000473:pathology; D002681:China; D002908:Chronic Disease; D004269:DNA, Bacterial / Q000737:chemistry / Q000235:genetics; D004275:DNA, Ribosomal / Q000737:chemistry / Q000235:genetics; D006651:Histocytochemistry; D006801:Humans; D041921:Hyphomicrobiaceae / Q000302:isolation & purification*; D008297:Male; D008853:Microscopy; D008875:Middle Aged; D012336:RNA, Ribosomal, 16S / Q000235:genetics; D012220:Rhinitis / Q000150:complications / Q000175:diagnosis* / Q000382:microbiology* / Q000473:pathology; D017422:Sequence Analysis, DNA; D017192:Skin Diseases, Bacterial / Q000175:diagnosis / Q000382:microbiology / Q000473:pathology; D014456:Ulcer / Q000175:diagnosis / Q000382:microbiology / Q000473:pathology
chemical_list: D004269:DNA, Bacterial; D004275:DNA, Ribosomal; D012336:RNA, Ribosomal, 16S