title: Is gene loss in pedigree dogs surprisingly rapid?
abstract: Factors affecting the probabilities of gene loss are discussed, with particular attention given to population expansion, sex ratio and inbreeding. Much of the variation in gene survival probabilities among breeds can be explained by differences in expansion rate, sex ratio and family size, with little or no influence of average inbreeding and population size.
authors.affiliation: Faculty of Veterinary Science, University of Sydney, NSW 2006, Australia. john.james@sydney.edu.au
authors.forename: John W
authors.initials: JW
authors.lastname: James
mesh_terms: D000818:Animals; D001947:Breeding / Q000706:statistics & numerical data; D004285:Dogs / Q000235:genetics*; D014644:Genetic Variation; D007178:Inbreeding; D010375:Pedigree; D011156:Population Density; D012744:Sex Ratio; D013045:Species Specificity