title: Hepatitis E Virus seroprevalence and chronic infections in patients with HIV, Switzerland.
abstract: We screened 735 HIV-infected patients in Switzerland with unexplained alanine aminotransferase elevation for hepatitis E virus (HEV) immunoglobulin G. Although HEV seroprevalence in this population is low (2.6%), HEV RNA can persist in patients with low CD4 cell counts. Findings suggest chronic HEV infection should be considered as a cause of persistent alanine aminotransferase elevation.
authors.affiliation: Centre Hospitalier Universitaire Vaudois and Lausanne University, Lausanne, Switzerland.
authors.forename: Alain
authors.initials: A
authors.lastname: Kenfak-Foguena
authors.forename: Franziska
authors.initials: F
authors.lastname: Schöni-Affolter
authors.forename: Phillippe
authors.initials: P
authors.lastname: Bürgisser
authors.forename: Andrea
authors.initials: A
authors.lastname: Witteck
authors.forename: Katharine E A
authors.initials: KE
authors.lastname: Darling
authors.forename: Helen
authors.initials: H
authors.lastname: Kovari
authors.forename: Laurent
authors.initials: L
authors.lastname: Kaiser
authors.forename: John-Marc
authors.initials: JM
authors.lastname: Evison
authors.forename: Luigia
authors.initials: L
authors.lastname: Elzi
authors.forename: Vanina
authors.initials: V
authors.lastname: Gurter-De La Fuente
authors.forename: Josef
authors.initials: J
authors.lastname: Jost
authors.forename: Darius
authors.initials: D
authors.lastname: Moradpour
authors.forename: Florence
authors.initials: F
authors.lastname: Abravanel
authors.forename: Jacques
authors.initials: J
authors.lastname: Izpopet
authors.forename: Matthais
authors.initials: M
authors.lastname: Cavassini
mesh_terms: D000914:Antibodies, Viral / Q000097:blood; D018791:CD4 Lymphocyte Count; D002908:Chronic Disease; D005260:Female; D015658:HIV Infections / Q000150:complications*; D016751:Hepatitis E / Q000150:complications* / Q000453:epidemiology* / Q000276:immunology / Q000821:virology; D016752:Hepatitis E virus / Q000235:genetics / Q000276:immunology; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D008297:Male; D012307:Risk Factors; D016036:Seroepidemiologic Studies; D013557:Switzerland / Q000453:epidemiology; D019562:Viral Load
chemical_list: D000914:Antibodies, Viral; D007074:Immunoglobulin G