title: Risk characterization for mercury, dichlorodiphenyltrichloroethane and polychlorinated biphenyls associated with fish consumption in Serbia.
abstract: The aim of this work was to assess the risk due to mercury (Hg), dichlorodiphenyltrichloroethane (DDT) and non-dioxin-like polychlorinated biphenyls (ndl PCBs) intake via fish consumption in Serbia. We have developed 24 scenarios using four concentration levels (mean, maximum, 50th and 95th percentile) of contaminants, determined in 521 samples of fish products available on Serbian market; two consumption levels (Food and Agriculture Organization/World Health Organization data and recommendation of American Heart Association); and three body weights (5th, 50th and 95th percentile). All the values concerning the intake of DDT are below the corresponding health based guidance value. Calculated weekly intake of Hg using maximal concentration, intake of 340g/week and 5th percentile of body weight exceeded the provisional tolerable weekly intake (PTWI). When maximal and 95th percentile concentration of ndl PCBs was used, weekly intakes exceeded a "guidance value" with one exception i.e., when 95th percentile of concentration along with 95th percentile of body weight were used. Concerning Hg and ndl PCBs, when extreme concentrations were used, HIs exceeded the value of 1, indicating that fish and fishery products may pose a threat to consumer's health.
authors.affiliation: Department of Toxicology, "Akademik Danilo Soldatovic", Belgrade University-Faculty of Pharmacy, Vojvode Stepe 450, 11221 Belgrade, Serbia. abiljana@pharmacy.bg.ac.rs
authors.forename: B
authors.initials: B
authors.lastname: Antonijevic
authors.forename: S
authors.initials: S
authors.lastname: Jankovic
authors.forename: M
authors.initials: M
authors.lastname: Curcic
authors.forename: K
authors.initials: K
authors.lastname: Durgo
authors.forename: E
authors.initials: E
authors.lastname: Stokic
authors.forename: B
authors.initials: B
authors.lastname: Srdic
authors.forename: D
authors.initials: D
authors.lastname: Tomic-Naglic
mesh_terms: D000818:Animals; D003634:DDT / Q000032:analysis*; D004435:Eating; D005396:Fish Products / Q000032:analysis*; D005506:Food Contamination / Q000032:analysis*; D006801:Humans; D008628:Mercury / Q000032:analysis*; D011078:Polychlorinated Biphenyls / Q000032:analysis*; D018570:Risk Assessment / Q000379:methods; D055771:Serbia
chemical_list: D003634:DDT; D011078:Polychlorinated Biphenyls; D008628:Mercury