title: Contact dermatitis caused by dimethylfumarate in Argentina.
abstract: For the first time in Argentina, we describe an outbreak of contact dermatitis. New pairs of shoes caused intense pruritus, pain, and eruption, followed by edema, blisters, and a severe negative impact on the epidermal barrier of the feet. We identify dimethylfumarate as the causal agent and suggest an analytical method for its fast identification.
authors.affiliation: Centro de Investigaciones Toxicológicas, Juan B. Alberdi 2986, Ciudad de Buenos Aires, Argentina. lbalbo55@yahoo.com
authors.forename: A
authors.initials: A
authors.lastname: Lo Balbo
authors.forename: M J
authors.initials: MJ
authors.lastname: Gotelli
authors.forename: W P
authors.initials: WP
authors.lastname: Mac Cormack
authors.forename: N
authors.initials: N
authors.lastname: Kogan
authors.forename: C
authors.initials: C
authors.lastname: Gotelli
mesh_terms: D000328:Adult; D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001118:Argentina; D001768:Blister / Q000209:etiology / Q000473:pathology; D003877:Dermatitis, Contact / Q000209:etiology* / Q000473:pathology; D000069462:Dimethyl Fumarate; D058872:Epidemics; D004890:Erythema / Q000473:pathology; D005260:Female; D005528:Foot / Q000473:pathology*; D005650:Fumarates / Q000009:adverse effects*; D005659:Fungicides, Industrial / Q000009:adverse effects* / Q000627:therapeutic use; D005839:Gentamicins / Q000627:therapeutic use; D006801:Humans; D006967:Hypersensitivity / Q000175:diagnosis; D008825:Miconazole / Q000627:therapeutic use; D010328:Patch Tests; D011537:Pruritus / Q000473:pathology; D011817:Rabbits; D012775:Shoes
chemical_list: D000900:Anti-Bacterial Agents; D005650:Fumarates; D005659:Fungicides, Industrial; D005839:Gentamicins; D008825:Miconazole; D000069462:Dimethyl Fumarate