title: Genotypes of rotavirus associated with acute gastroenteritis in Seoul, Korea.
abstract: Acute viral gastroenteritis is one of the most common infectious diseases in infants and young children. Rotavirus is mainly important in childhood. The present study determined the detection rate, seasonality and G and P genotypes of rotaviruses in children hospitalized for acute gastroenteritis in Seoul, Korea in 2009. A total of 1,423 stool specimens were screened by ELISA for the presence of rotavirus antigens and the rotavirus-positive stools genotyped by RT-PCR. The G genotype was determined for 90% of samples (242/269) and the P genotype for 93.3% (251/269). During the study, 25 G-P combinations were detected with G1P[8] in 38.3% (n= 103) and G4P[6] in 5.9% (n= 16) cases. These data provided information on rotavirus in patients with acute gastroenteritis in Seoul, Korea and provided baseline data to motivate for the implementation of control measures for rotavirus disease.
authors.affiliation: Virus Team, Seoul Metropolitan Government Research Institute of Public Health and Environment, 202-3 Yangjae-Dong, Seocho-Gu, Seoul 137-734, Korea. sanghun93@seoul.go.kr
authors.forename: Sanghun
authors.initials: S
authors.lastname: Park
authors.forename: Seah
authors.initials: S
authors.lastname: Oh
authors.forename: Jibho
authors.initials: J
authors.lastname: Lee
authors.forename: Gunyong
authors.initials: G
authors.lastname: Park
authors.forename: Sungmin
authors.initials: S
authors.lastname: Choi
authors.forename: Youngzoo
authors.initials: Y
authors.lastname: Chae
authors.forename: Hyunsoo
authors.initials: H
authors.lastname: Kim
mesh_terms: D000956:Antigens, Viral / Q000032:analysis; D002675:Child, Preschool; D004797:Enzyme-Linked Immunosorbent Assay; D005243:Feces / Q000821:virology; D005260:Female; D005759:Gastroenteritis / Q000453:epidemiology* / Q000821:virology*; D005838:Genotype; D006760:Hospitalization; D006801:Humans; D015994:Incidence; D007223:Infant; D007723:Korea / Q000453:epidemiology; D008297:Male; D012367:RNA, Viral / Q000032:analysis; D011995:Recombination, Genetic; D020133:Reverse Transcriptase Polymerase Chain Reaction; D012401:Rotavirus / Q000145:classification* / Q000235:genetics* / Q000302:isolation & purification; D012400:Rotavirus Infections / Q000453:epidemiology* / Q000821:virology*; D012621:Seasons
chemical_list: D000956:Antigens, Viral; D012367:RNA, Viral