title: [Content of CD4+ CD25+ regulatory T cells in peripheral blood lymphocytes in patients with allergic rhinitis].
abstract: OBJECTIVE
  To investigate the change of CD4- CD25 regulatory T cells (Tregs) of peripheral blood in allergic rhinitis (AR) patients.
  
  
  METHODS
  T lymphocytes of twenty AR patients and eight healthy subjects were separated and the flow cytometry was used to measure the percentage of CD4+ CD25+ Treg.
  
  
  RESULTS
  Compared with control group, the percentage of Treg and CD4- CD25high Tregs of AR patients was decreased significantly (P < 0.05).
  
  
  CONCLUSIONS
  The proportion of CD4+ CD25+ Tregs decreased in AR patients conspicuously, which might be one of the pathogenesis of AR.
authors.affiliation: Department of Otolaryngology, Huadong Hospital, Fudan University, Shanghai, 200040, China.
authors.forename: Shaoqing
authors.initials: S
authors.lastname: Yu
authors.forename: Yingjian
authors.initials: Y
authors.lastname: Chen
authors.forename: Jie
authors.initials: J
authors.lastname: Zhang
authors.forename: Zhiqiang
authors.initials: Z
authors.lastname: Yan
authors.forename: Ruxin
authors.initials: R
authors.lastname: Zhang
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D005260:Female; D005434:Flow Cytometry; D006801:Humans; D053645:Interleukin-2 Receptor alpha Subunit / Q000276:immunology / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D012221:Rhinitis, Allergic, Perennial / Q000097:blood* / Q000276:immunology; D050378:T-Lymphocytes, Regulatory / Q000276:immunology / Q000378:metabolism*; D055815:Young Adult
chemical_list: D053645:Interleukin-2 Receptor alpha Subunit