title: Molecular basis of sulfonamide and trimethoprim resistance in fish-pathogenic Aeromonas isolates.
abstract: Sulfonamide-trimethoprim-resistant Aeromonas salmonicida and motile Aeromonas spp. from diseased fish of the GERM-Vet study carried the sul1 gene together with mostly cassette-borne trimethoprim resistance genes, including the novel gene dfrA28. The seven dfrA and dfrB genes identified were located mostly in class 1 integrons which commonly harbored other gene cassettes.
authors.affiliation: Institute of Farm Animal Genetics, Friedrich-Loeffler-Institut (FLI), Höltystr. 10, 31535 Neustadt-Mariensee, Germany. kristina.kadlec@fli.bund.de
authors.forename: Kristina
authors.initials: K
authors.lastname: Kadlec
authors.forename: Ellen
authors.initials: E
authors.lastname: von Czapiewski
authors.forename: Heike
authors.initials: H
authors.lastname: Kaspar
authors.forename: Jürgen
authors.initials: J
authors.lastname: Wallmann
authors.forename: Geovana Brenner
authors.initials: GB
authors.lastname: Michael
authors.forename: Ulrike
authors.initials: U
authors.lastname: Steinacker
authors.forename: Stefan
authors.initials: S
authors.lastname: Schwarz
mesh_terms: D048409:Aeromonas salmonicida / Q000187:drug effects* / Q000235:genetics / Q000302:isolation & purification; D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D004269:DNA, Bacterial / Q000235:genetics; D024881:Drug Resistance, Bacterial; D005393:Fish Diseases / Q000382:microbiology*; D005399:Fishes; D023061:Gene Order; D005798:Genes, Bacterial; D016905:Gram-Negative Bacterial Infections / Q000382:microbiology / Q000662:veterinary*; D032023:Integrons; D013449:Sulfonamides / Q000494:pharmacology*; D014295:Trimethoprim / Q000494:pharmacology*
chemical_list: D000900:Anti-Bacterial Agents; D004269:DNA, Bacterial; D013449:Sulfonamides; D014295:Trimethoprim