title: Gastric fundic gland polyps and their relationship to colorectal neoplasia in Koreans: a 16-year retrospective study.
abstract: OBJECTIVE
  There is an ongoing debate on the relationship between gastric fundic gland polyps and increased incidence of colorectal neoplasia in Caucasians. However, there was no report on the relationship between gastric fundic gland polyp and colorectal neoplasia in Korea. The aim of this study was to identify the characteristics of gastric fundic gland polyps and whether a relationship exists between fundic gland polyps and colorectal neoplasia in Korean population.
  
  
  METHODS
  Persons who underwent an esophagogastroduodenoscopy and colonoscopy from 1992 to 2007 at the Health Promotion Center of Incheon St. Mary's Hospital, The Catholic University of Korea were reviewed retrospectively. The relationship between gastric fundic gland polyps and colorectal neoplasia were analyzed.
  
  
  RESULTS
  Among 22,451 subjects, fundic gland polyps were found in 328 subjects (1.5%). Fundic gland polyps were more common in women than in men (odds ratio of 6.25; 95% CI of 4.68-8.34). The odds ratios for colorectal neoplasia in all subjects with gastric fundic gland polyps were 0.56 (95% CI of 0.33-0.95) and men who were 50 years of age or older had an odds ratio of 2.81 (95% CI of 1.03-7.66) as compared to the control group. However, age and sex-adjusted odds ratios for all gastric fundic gland polyps were 0.73 (95% CI of 0.42-1.26), for men 1.78 (95% CI of 0.80-3.98), and for women 0.37 (95% CI of 0.16-0.87).
  
  
  CONCLUSIONS
  Surveillance colonoscopy in patients with fundic gland polyps can be performed in the same manner as general population in Korea.
authors.affiliation: Department of Internal Medicine, The Catholic University of Korea, College of Medicine, Seoul, Korea.
authors.forename: Sun-Mee
authors.initials: SM
authors.lastname: Hwang
authors.forename: Byung-Wook
authors.initials: BW
authors.lastname: Kim
authors.forename: Hiun-Suk
authors.initials: HS
authors.lastname: Chae
authors.forename: Bo-In
authors.initials: BI
authors.lastname: Lee
authors.forename: Hwang
authors.initials: H
authors.lastname: Choi
authors.forename: Jeong-Seon
authors.initials: JS
authors.lastname: Ji
authors.forename: Kyu-Yong
authors.initials: KY
authors.lastname: Choi
authors.forename: In-Sik
authors.initials: IS
authors.lastname: Chung
authors.forename: Lee-So
authors.initials: LS
authors.lastname: Maeng
mesh_terms: D000328:Adult; D000367:Age Factors; D015179:Colorectal Neoplasms / Q000453:epidemiology* / Q000473:pathology; D016099:Endoscopy, Gastrointestinal; D005260:Female; D005748:Gastric Fundus / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D011127:Polyps / Q000453:epidemiology* / Q000473:pathology; D056910:Republic of Korea; D012189:Retrospective Studies; D012737:Sex Factors