title: Conjugate addition-initiated Nazarov cyclization.
abstract: A reaction sequence involving the 1,6-conjugate addition of a nucleophile to a dienyl diketone followed by Nazarov cyclization is described. Several nucleophiles are identified as competent initiators for the sequence. A different reaction outcome is observed when catalytic amounts of nucleophile are employed, involving elimination of the nucleophile after the electrocyclization.
authors.affiliation: Department of Chemistry, University of Rochester, Rochester, New York 14627, United States.
authors.forename: Joshua L
authors.initials: JL
authors.lastname: Brooks
authors.forename: Patrick A
authors.initials: PA
authors.lastname: Caruana
authors.forename: Alison J
authors.initials: AJ
authors.lastname: Frontier
mesh_terms: D002384:Catalysis; D003500:Cyclization; D007659:Ketones / Q000737:chemistry*; D008958:Models, Molecular
chemical_list: D007659:Ketones