title: [A case of multiple metastases breast cancer controlled using S-1 as third-line chemotherapy].
abstract: A 42-year-old female underwent surgery for cancer of the left breast (T3N2M0) in February 2003, and FEC 70, followed by CMF, was administered as adjuvant therapy. In January 2009, second-line chemotherapy with weekly paclitaxel therapy was started after multiple pleural and bone metastatic lesions had been found. Despite this treatment, she required radiation therapy for the growth of bone metastatic lesions. As paclitaxel apparently had no useful effect on the lesions, S-1 chemotherapy, given as third-line therapy starting in December 2009, was considered useful for disease control without progression demonstrated by PET evaluation.
authors.affiliation: Dept. of Surgery, Nemuro City Hospital, Japan.
authors.forename: Futoshi
authors.initials: F
authors.lastname: Nakajima
authors.forename: Koji
authors.initials: K
authors.lastname: Matsuoka
authors.forename: Tadashi
authors.initials: T
authors.lastname: Ogawa
authors.forename: Hiroki
authors.initials: H
authors.lastname: Nomura
authors.forename: Jun
authors.initials: J
authors.lastname: Araya
mesh_terms: D000328:Adult; D000964:Antimetabolites, Antineoplastic / Q000627:therapeutic use*; D001859:Bone Neoplasms / Q000188:drug therapy* / Q000556:secondary; D001943:Breast Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D004338:Drug Combinations; D005260:Female; D006801:Humans; D010094:Oxonic Acid / Q000627:therapeutic use*; D010997:Pleural Neoplasms / Q000188:drug therapy* / Q000556:secondary; D049268:Positron-Emission Tomography; D012008:Recurrence; D016879:Salvage Therapy; D005641:Tegafur / Q000627:therapeutic use*
chemical_list: D000964:Antimetabolites, Antineoplastic; D004338:Drug Combinations; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid