title: Validity of the hangover symptoms scale: evidence from an electronic diary study.
abstract: BACKGROUND
  The Hangover Symptoms Scale (HSS) assesses the frequency of 13 symptoms experienced after drinking in the past year. Cross-sectional analyses in college drinkers showed preliminary evidence for the validity of the HSS (Slutske et al., 2003). The current investigation extended this work by examining the construct validity of the HSS in an ecological momentary assessment investigation.
  
  
  METHODS
  Frequent drinkers (N = 404) carried electronic diaries to track their daily experiences over 3 weeks. Each morning, the diary assessed prior-night drinking behaviors, the presence of current hangover, and intensity of current headache and nausea.
  
  
  RESULTS
  Adjusting for sex and body mass, the HSS significantly predicted diary endorsement of hangover (OR = 2.11, 95% CI = 1.78 to 2.49, p < 0.001). Participants who endorsed the HSS headache and nausea items were especially likely to report the elevations of corresponding symptoms in diary records made the morning after drinking. HSS scores incrementally predicted hangover when the number of drinks consumed in the episode was covaried but did not moderate the relationship between the number of drinks and diary hangover reports.
  
  
  CONCLUSIONS
  The HSS appears to be a valid tool for hangover research. Higher HSS scores identify individuals who complain of "real world" hangovers and who may be especially likely to display particular symptoms after a night of drinking. Past hangovers predicted future hangovers, suggesting hangovers do not necessarily discourage or inhibit future drinking, at least across the several-week time interval studied here. There is a need to develop and evaluate complementary measures that can more directly index individual differences in hangover susceptibility in survey designs.
authors.affiliation: Midwest Alcoholism Research Center, Washington University School of Medicine, St. Louis, Missouri, USA.
authors.forename: Brandon M
authors.initials: BM
authors.lastname: Robertson
authors.forename: Thomas M
authors.initials: TM
authors.lastname: Piasecki
authors.forename: Wendy S
authors.initials: WS
authors.lastname: Slutske
authors.forename: Phillip K
authors.initials: PK
authors.lastname: Wood
authors.forename: Kenneth J
authors.initials: KJ
authors.lastname: Sher
authors.forename: Saul
authors.initials: S
authors.lastname: Shiffman
authors.forename: Andrew C
authors.initials: AC
authors.lastname: Heath
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000428:Alcohol Drinking / Q000009:adverse effects* / Q000453:epidemiology; D000435:Alcoholic Intoxication / Q000453:epidemiology*; D003430:Cross-Sectional Studies; D005260:Female; D006261:Headache / Q000453:epidemiology* / Q000209:etiology; D006801:Humans; D008297:Male; D008499:Medical Records / Q000592:standards*; D008875:Middle Aged; D009325:Nausea / Q000453:epidemiology* / Q000209:etiology; D012189:Retrospective Studies; D055815:Young Adult