title: Dietary conjugated linoleic acid and long-chain n-3 fatty acids in mammary and prostate cancer protection: a review.
abstract: The role of dietary fatty acids on cancer is still controversial. To examine the current literature on the protective role of conjugated linoleic acid (CLA) and marine long-chain fatty acids [eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA)] and the risk of breast and prostate cancer, data from 41 case-control and cohort studies and relevant in vitro and animal experiments were included in this 2000-2010 revision. Epidemiological studies on CLA intake or its tissue concentration related to breast and prostate tumorigenesis are not conclusive; EPA and DHA intake have shown important inverse associations just in some studies. Additional research on the analysed association is required.
authors.affiliation: Facultad de Ciencias de la Salud, Universidad Adventista del Plata, 25 de Mayo 99, 3103 Libertador San Martín, Entre Ríos, Argentina. vheinze@hotmail.com
authors.forename: Verónica M
authors.initials: VM
authors.lastname: Heinze
authors.forename: Adriana B
authors.initials: AB
authors.lastname: Actis
mesh_terms: D001943:Breast Neoplasms / Q000517:prevention & control*; D004041:Dietary Fats / Q000627:therapeutic use*; D004281:Docosahexaenoic Acids / Q000627:therapeutic use*; D015118:Eicosapentaenoic Acid / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D019787:Linoleic Acid / Q000627:therapeutic use; D044243:Linoleic Acids, Conjugated / Q000627:therapeutic use*; D008297:Male; D011471:Prostatic Neoplasms / Q000517:prevention & control*
chemical_list: D004041:Dietary Fats; D044243:Linoleic Acids, Conjugated; D004281:Docosahexaenoic Acids; D019787:Linoleic Acid; D015118:Eicosapentaenoic Acid