title: Lower sense of coherence, negative religious coping, and disease severity as indicators of a decrease in quality of life in Iranian family caregivers of relatives with breast cancer during the first 6 months after diagnosis.
abstract: BACKGROUND
  Breast cancer challenges not only the patients who suffer from the disease but also their family caregivers. Little is known about how Iranian family caregivers are influenced.
  
  
  OBJECTIVE
  The objective of the study was to describe quality of life (QoL), well-being, sense of coherence (SOC), spirituality, and religious coping in family caregivers of patients with breast cancer at the time of diagnosis (T1) and 6 months after diagnosis (T2) and identify predictive factors of change in QoL.
  
  
  METHODS
  Data were collected from 150 family caregivers. The Persian version of Caregiver Quality of Life Index-Cancer, Sense of Coherence Scale, Spirituality Perspective Scale, Religious Coping Scale, and the Health Index were used at T1 and T2.
  
  
  RESULTS
  The results showed significant increase in overall QoL (P = .00) and well-being (P = .03) at T2. However, ratings of their SOC (P = .03), spirituality (P = .01), and negative religious coping (P = .00) decreased. Multiple regression analyses revealed the rating of QoL at T1 as the strongest predictor in the rating of quality-of-life change at T2 followed by the degree of SOC, negative religious coping, and patients having more severe breast cancer (R² = 0.64).
  
  
  CONCLUSIONS
  Despite improved QoL in the sample from diagnosis to 6 months, family caregivers struggle to cope with the situation.
  
  
  CONCLUSIONS
  It is suggested to develop and investigate the effects of support programs targeting coping ability in Iranian family caregivers to women with breast cancer.
authors.affiliation: Nursing Division, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden. sedigheh.khanjari@ki.se
authors.forename: Sedigheh
authors.initials: S
authors.lastname: Khanjari
authors.forename: Fatemeh
authors.initials: F
authors.lastname: Oskouie
authors.forename: Ann
authors.initials: A
authors.lastname: Langius-Eklöf
mesh_terms: D000223:Adaptation, Psychological; D000328:Adult; D001943:Breast Neoplasms / Q000175:diagnosis / Q000523:psychology*; D017028:Caregivers / Q000523:psychology*; D005195:Family Relations; D005260:Female; D006305:Health Status Indicators; D006801:Humans; D007492:Iran; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011788:Quality of Life / Q000523:psychology*; D012069:Religion and Psychology; D060685:Sense of Coherence; D012720:Severity of Illness Index; D013997:Time Factors