title: [A case of long-term remission of small-cell lung cancer with multiple brain metastases].
abstract: The prognosis for patients with brain metastases of small-cell lung cancer is particularly dismal. We present a case of a 47- year-old man diagnosed with multiple brain tumors which, following surgery, were revealed to be metastatic small-cell lung carcinoma through a pathological examination and a subsequent post-operative chest CT. Whole brain irradiation (50 Gy) with ten courses of systemic chemotherapy (carboplatin 200 mg/m2 day 1; etoposide 60 mg/m2 day 1-5) was applied. On the radiological examination, the lesions of the lung and brain gradually disappeared three and five years after the diagnosis, respectively. Sixteen years after diagnosis of the metastatic small cell carcinoma, the patient is disease-free and his ADL is excellent. This is an extremely rare case of small-cell lung cancer with multiple brain metastases in terms of showing a long- term remission.
authors.affiliation: Dept. of Neurosurgery, Karatsu Red Cross Hospital, Japan.
authors.forename: Naoshi
authors.initials: N
authors.lastname: Hagihara
authors.forename: Kazuo
authors.initials: K
authors.lastname: Tabuchi
mesh_terms: D001932:Brain Neoplasms / Q000556:secondary* / Q000628:therapy; D003131:Combined Modality Therapy; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology* / Q000628:therapy; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D012074:Remission Induction; D055752:Small Cell Lung Carcinoma / Q000473:pathology* / Q000628:therapy; D013997:Time Factors; D014057:Tomography, X-Ray Computed