title: Spontaneous resolution of diabetes insipidus after cranioplasty and cranial defect repair.
abstract: We describe the resolution of persistent diabetes insipidus after cranioplasty with autogenous bone and bone morphogentic protein 2-infused collagen matrix in a patient who had large bilateral craniectomies for trauma. A potential pathogenic mechanism is presented.
authors.affiliation: University of Oklahoma School of Medicine, Oklahoma, Oklahoma, USA.
authors.forename: Josephine J
authors.initials: JJ
authors.lastname: Sung
authors.forename: Timothy B
authors.initials: TB
authors.lastname: Mapstone
authors.forename: Christian A
authors.initials: CA
authors.lastname: El-Amm
mesh_terms: D000203:Activities of Daily Living; D000293:Adolescent; D055396:Bone Morphogenetic Protein 2 / Q000008:administration & dosage / Q000627:therapeutic use; D016025:Bone Transplantation / Q000379:methods; D001930:Brain Injuries / Q000601:surgery*; D003094:Collagen; D056424:Decompressive Craniectomy / Q000379:methods; D003919:Diabetes Insipidus / Q000503:physiopathology*; D004337:Drug Carriers; D005260:Female; D005500:Follow-Up Studies; D005547:Foreign Bodies / Q000601:surgery; D005597:Fractures, Open / Q000601:surgery; D005624:Frontal Bone / Q000293:injuries / Q000601:surgery; D006801:Humans; D019651:Plastic Surgery Procedures / Q000379:methods*; D020127:Recovery of Function / Q000502:physiology; D012075:Remission, Spontaneous; D020204:Skull Fracture, Depressed / Q000601:surgery; D014934:Wood
chemical_list: C525718:BMP2 protein, human; D055396:Bone Morphogenetic Protein 2; D004337:Drug Carriers; D003094:Collagen