title: Postural instability, frontotemporal dementia, and ophthalmoplegia: clinicopathological case.
abstract: A 56-year-old man presented with gait disturbance, personality change, and behavioral disturbances. He subsequently developed falls, postural instability, and axial rigidity. The cognitive problems progressed and he developed aphasia and later eye movement abnormalities. He died after 9 years of disease. Experts discuss the syndromal diagnosis and predict the underlying pathology. The pathological diagnosis is given and clinical learning points are considered.
authors.affiliation: Movement Disorders Unit, Neurology Service, Federal University of Minas Gerais, Belo Horizonte, Brazil.
authors.forename: Francisco
authors.initials: F
authors.lastname: Cardoso
authors.forename: John
authors.initials: J
authors.lastname: Hodges
authors.forename: Andrew H
authors.initials: AH
authors.lastname: Evans
authors.forename: Tamas
authors.initials: T
authors.lastname: Revesz
authors.forename: David R
authors.initials: DR
authors.lastname: Williams
mesh_terms: D005625:Frontal Lobe / Q000378:metabolism; D057180:Frontotemporal Dementia / Q000150:complications* / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009886:Ophthalmoplegia / Q000150:complications* / Q000473:pathology; D011187:Posture / Q000502:physiology*; D012678:Sensation Disorders / Q000150:complications* / Q000473:pathology; D016875:tau Proteins / Q000378:metabolism
chemical_list: D016875:tau Proteins