title: Enhancers: from developmental genetics to the genetics of common human disease.
abstract: In mammals, long-range gene regulation became apparent through simple Mendelian disease genetics in human and developmental genetics in the mouse. Can the insights into gene control, provided by the study of these enhancers, help us understand the functional significance of sequence variation associated with common/complex human disease and quantitative traits?
authors.affiliation: MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, Crewe Road, Edinburgh, UK.
authors.forename: Iain
authors.initials: I
authors.lastname: Williamson
authors.forename: Robert E
authors.initials: RE
authors.lastname: Hill
authors.forename: Wendy A
authors.initials: WA
authors.lastname: Bickmore
mesh_terms: D000818:Animals; D015509:Developmental Biology; D004194:Disease / Q000235:genetics*; D004742:Enhancer Elements, Genetic / Q000235:genetics*; D005786:Gene Expression Regulation / Q000235:genetics*; D006801:Humans