title: Screening and treatment of dyslipidemias in children and adolescents.
abstract: OBJECTIVE
  Cardiovascular disease is the most prominent cause of mortality worldwide. A key risk factor for atherosclerotic cardiovascular disease is the presence of dyslipidemia. Clinical approaches to evaluation and treatment of dyslipidemia in children and adolescents are presented.
  
  
  METHODS
  A review of published guidelines and presentation of illustrative cases.
  
  
  RESULTS
  Dyslipidemia is an important risk factor in early-stage atherosclerosis. Children and adolescents at high risk for dyslipidemia can be identified using a positive family history or the presence of other risk factors as a trigger. Once high-risk individuals are identified, primary treatment is lifestyle modification. In cases where low-density lipoprotein-cholesterol is high, pharmacologic intervention may be needed.
  
  
  CONCLUSIONS
  Screening of appropriate children and adolescents for dyslipidemia and treating those at high risk are important for the long-term prevention of cardiovascular disease.
authors.affiliation: Department of Pediatrics, University of Colorado, Denver School of Medicine, Aurora, CO 80045, USA. daniels.stephen@tchden.org
authors.forename: S R
authors.initials: SR
authors.lastname: Daniels
mesh_terms: D000293:Adolescent; D000368:Aged; D002318:Cardiovascular Diseases / Q000517:prevention & control*; D002648:Child; D002675:Child, Preschool; D008078:Cholesterol, LDL / Q000097:blood; D050171:Dyslipidemias / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D005192:Family Health; D005260:Female; D006801:Humans; D008019:Life Style; D008297:Male; D008403:Mass Screening; D008875:Middle Aged; D009765:Obesity / Q000150:complications / Q000628:therapy; D012307:Risk Factors
chemical_list: D008078:Cholesterol, LDL