title: Exposure factors that contribute to variability in toxic responses in man.
abstract: The route of exposure is an important determinant of the internal dose of a chemical in man and the expression of toxicity. Routes of exposure are inhalation via the lung and dermal penetration, and the degree of absorption and first pass metabolism vary between chemicals. Inter-individual differences in metabolism of both genetic and environmental cause contribute to variability in metabolic fate and toxic response.
authors.forename: F M
authors.initials: FM
authors.lastname: Williams