title: The impact of developmental biology on pluripotent stem cell research: successes and challenges.
abstract: Research on developmental pathways in model organisms provides key information on how to isolate, maintain, and differentiate human pluripotent stem cells. However, details of developmental pathways differ even across mammalian species. Full realization of the potential of stem cells will require more direct studies of human or primate developmental biology.
authors.affiliation: Program in Developmental and Stem Cell Biology, Hospital for Sick Children, University of Toronto, 555 University Avenue, Toronto,Ontario, Canada. janet.rossant@sickkids.ca
authors.forename: Janet
authors.initials: J
authors.lastname: Rossant
mesh_terms: D000818:Animals; D002454:Cell Differentiation; D065150:Cellular Reprogramming; D015509:Developmental Biology; D006801:Humans; D051379:Mice; D039904:Pluripotent Stem Cells / Q000166:cytology*; D057905:Stem Cell Research