title: Reliability and validity of the Chinese version of the neuropsychiatric inventory in mainland China.
abstract: OBJECTIVE
  The reliability and validity of the Chinese version of the neuropsychiatric inventory (CNPI) in patients with Alzheimer's disease (AD) have not been assessed in mainland China. We do the reliability and validity research about CNPI of mainland China in the present study.
  
  
  METHODS
  The CNPI was administered to 219 caregivers of patients with AD. Each caregiver was retested 4 weeks after initial testing.
  
  
  RESULTS
  The Cronbach's α coefficient of the total symptom scale was 0.69. The Cronbach's α coefficient of the total caregiver distress subscale was 0.72. The Cronbach's α coefficient of the entire inventory was 0.82. The test-retest coefficients ranged from 0.66 to 0.98 (p < 0.001). Principal axis factoring analysis of the symptom subscale yielded a five-factor solution, which contributed to 67.0% of the cumulative variance. Factor 1, which included aberrant motor behavior, hallucinations, delusion and irritability had the most significant contribution to the cumulative variance. Principal axis factoring analysis of the caregiver distress subscale also yielded a five-factor solution, which contributed to 70.2% of the cumulative variance. Factor 1, which included depression, delusion, sleep/night behavior, aberrant motor behavior and irritability had the most significant contribution to the cumulative variance.
  
  
  CONCLUSIONS
  This Chinese version of NPI is a reliable and valid tool for measuring neuropsychiatric disturbances in patients with AD.
authors.affiliation: Department of Geriatric Psychiatry, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
authors.forename: Tao
authors.initials: T
authors.lastname: Wang
authors.forename: Shifu
authors.initials: S
authors.lastname: Xiao
authors.forename: Xia
authors.initials: X
authors.lastname: Li
authors.forename: Haihong
authors.initials: H
authors.lastname: Wang
authors.forename: Yuanyuan
authors.initials: Y
authors.lastname: Liu
authors.forename: Ning
authors.initials: N
authors.lastname: Su
authors.forename: Yiru
authors.initials: Y
authors.lastname: Fang
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000451:nursing / Q000523:psychology; D017028:Caregivers / Q000523:psychology*; D002681:China; D005163:Factor Analysis, Statistical; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests / Q000592:standards*; D015203:Reproducibility of Results; D013315:Stress, Psychological / Q000175:diagnosis*; D011795:Surveys and Questionnaires / Q000592:standards