title: In vivo efficacy of praziquantel against Echinoparyphium aconiatum (Trematoda: Echinostomatidae) parasitizing the great pond snails Lymnaea stagnalis (Gastropoda: Lymnaeidae).
abstract: The present study had a practical goal. I aimed to determine whether praziquantel could reduce the production of Echinoparyphium aconiatum (Trematoda: Echinostomatidae) cercariae in infected snails Lymnaea stagnalis (Gastropoda: Lymnaeidae) without killing the hosts. Praziquantel is a broad-spectrum antihelminth agent. It caused a total cessation of cercaria shedding when the praziquantel concentration in the treatment bath was 10 mg/L and the treatment time was 30 h or longer. A next research step which has to be taken before giving detailed recommendations about using praziquantel for ceasing production of E. aconiatum cercariae in parasitized snails is to follow the survivorship and performance of treated snails after a praziquantel exposure for longer than in this medium-term (3 days) experiment.
authors.affiliation: Department of Biology, University of Eastern Finland, Joensuu Campus, P.O. Box 111, FI-80101 Joensuu, Finland. ari.voutilainen@uef.fi
authors.forename: Ari
authors.initials: A
authors.lastname: Voutilainen
mesh_terms: D000704:Analysis of Variance; D000818:Animals; D000871:Anthelmintics / Q000494:pharmacology*; D004450:Echinostomatidae / Q000187:drug effects* / Q000502:physiology; D005618:Fresh Water; D006790:Host-Parasite Interactions / Q000187:drug effects; D008195:Lymnaea / Q000469:parasitology*; D011223:Praziquantel / Q000494:pharmacology*
chemical_list: D000871:Anthelmintics; D011223:Praziquantel