title: Prognosis according to the timing of percutaneous coronary intervention in non-ST segment elevation myocardial infarction, based on the Korean Acute Myocardial Infarction Registry (KAMIR).
abstract: BACKGROUND
  Patients with acute coronary syndrome without ST-segment elevation (ACS- -NSTE) are at risk for adverse cardiac events. Based on data in the Korean Acute Myocardial Infarction Registry (KAMIR), we analyzed the prognosis according to the timing of percutaneous coronary intervention (PCI) in patients with NSTEMI in Korea.
  
  
  RESULTS
  2,455 patients with NSTEMI in KAMIR were classified according to the time interval from the onset of cardiac symptoms to PCI. Patients in Group I underwent PCI within 24 hours of the onset of symptoms; in Group II between 24 and 48 hours; and in Group III after 48 hours. Major adverse cardiac events (MACEs) are defined as cardiac death, non-cardiac death, myocardial infarction, revascularization and coronary-artery bypass graft surgery. The MACEs were compared between groups. Of the 2,455 patients, 743 (30.2%) were assigned to Group I, 583 (23.7%) to Group II, and 1,129 (45.9%) to Group III. The total incidence of MACEs was higher in Group I than Group III, and similar between Groups I and II (Group I: 15.1%, Group II: 14.4%, Group III: 11.6%, p = 0.053). The incidence of MACEs in the intermediate TIMI risk score group had decreased as the intervention time was delayed.
  
  
  CONCLUSIONS
  The prognosis according to the timing of PCI in patients with NSTEMI was similar based on the data in KAMIR. TIMI risk score was related to a high incidence of MACEs.
authors.affiliation: Division of Cardiology, Department of Internal Medicine, College of Medicine, Pusan National University, 10 Ami-dong 1-ga Seo-gu, Busan, Korea.
authors.forename: Jin-Sup
authors.initials: JS
authors.lastname: Park
authors.forename: Han Cheol
authors.initials: HC
authors.lastname: Lee
authors.forename: Hye-Won
authors.initials: HW
authors.lastname: Lee
authors.forename: Sung Gyu
authors.initials: SG
authors.lastname: Ahn
authors.forename: Kwang Soo
authors.initials: KS
authors.lastname: Cha
authors.forename: Taek Jong
authors.initials: TJ
authors.lastname: Hong
authors.forename: Sang-Pil
authors.initials: SP
authors.lastname: Kim
authors.forename: Yeong Dae
authors.initials: YD
authors.lastname: Kim
authors.forename: Sang-Kwon
authors.initials: SK
authors.lastname: Lee
authors.forename: Hae Kyu
authors.initials: HK
authors.lastname: Kim
authors.forename: Myung Ho
authors.initials: MH
authors.lastname: Jeong
mesh_terms: D000368:Aged; D000704:Analysis of Variance; D015906:Angioplasty, Balloon, Coronary / Q000009:adverse effects / Q000401:mortality; D016009:Chi-Square Distribution; D017023:Coronary Angiography; D001026:Coronary Artery Bypass; D005260:Female; D006331:Heart Diseases / Q000209:etiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000000981:diagnostic imaging / Q000401:mortality / Q000628:therapy*; D016016:Proportional Hazards Models; D012008:Recurrence; D012042:Registries; D056910:Republic of Korea; D018570:Risk Assessment; D012307:Risk Factors; D013997:Time Factors; D016896:Treatment Outcome