title: From Hen House to Bedside: Tracing Hanafusa's Legacy from Avian Leukemia Viruses to SRC to ABL and Beyond.
abstract: The discovery of the Src oncogene was the first step on a long journey toward improved cancer chemotherapy. In this review, we explore Src and BCR-ABL, signal transduction, and recent advances in oncogene addiction and celebrate Hidesaboro Hanafusa and the many researchers who ushered in the age of target-directed therapy against tyrosine kinase oncoproteins.
authors.affiliation: Division of Hematology, Brigham and Women's Hospital, Boston, MA, USA.
authors.forename: Michael G
authors.initials: MG
authors.lastname: Kharas
authors.forename: George Q
authors.initials: GQ
authors.lastname: Daley