title: Characterization and antibacterial efficacy of silver-coated Ca-Na-Zn-Si/Ti glasses.
abstract: A glass series [xSiO₂[-y])·0.36ZnO·0.17Na₂O·0.05CaO (starting at x = 0.50, y = 0.08 TiO₂)] was formulated with TiO₂ substituting SiO₂. Each glass/silver-coated glass was characterized using X-ray diffraction, X-ray photoelectron spectroscopy (XPS), and scanning electron microscopy. Surface area analysis revealed significant changes after silver coating, 0.43-0.95 m²/g (control), to 0.53-1.85 m²/g (AU-1), and 0.20-1.11 m²/g (AU-2). Ion release from uncoated glasses included sodium (0.08 mg/L), calcium (0.07 mg/L), and zinc (0.008 mg/L), where silver-coated glasses presented 0.42 mg/L (silver), 0.33 mg/L (sodium), 0.02 mg/L (calcium), and 0.01 mg/L (zinc). Ag-coated glasses presented inhibition zones of 7.75 mm (control) compared to 1.04 mm (AU-2).
authors.affiliation: Inamori School of Engineering, Alfred University, 1 Saxon Drive, Alfred, NY 14802, USA. wren@alfred.edu
authors.forename: Anthony
authors.initials: A
authors.lastname: Wren
authors.forename: Betul
authors.initials: B
authors.lastname: Akgun
authors.forename: Brian
authors.initials: B
authors.lastname: Adams
authors.forename: Aisling
authors.initials: A
authors.lastname: Coughlan
authors.forename: Nathan
authors.initials: N
authors.lastname: Mellott
authors.forename: Mark
authors.initials: M
authors.lastname: Towler
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000494:pharmacology*; D002118:Calcium / Q000737:chemistry; D020099:Coated Materials, Biocompatible / Q000737:chemistry* / Q000494:pharmacology*; D004926:Escherichia coli / Q000187:drug effects; D004927:Escherichia coli Infections / Q000188:drug therapy; D005898:Glass / Q000737:chemistry*; D006801:Humans; D056951:Photoelectron Spectroscopy; D012834:Silver / Q000737:chemistry* / Q000494:pharmacology*; D012964:Sodium / Q000737:chemistry; D014025:Titanium / Q000737:chemistry; D014961:X-Ray Diffraction; D015032:Zinc / Q000737:chemistry
chemical_list: D000900:Anti-Bacterial Agents; D020099:Coated Materials, Biocompatible; C009495:titanium dioxide; D012834:Silver; D012964:Sodium; D014025:Titanium; D015032:Zinc; D002118:Calcium