title: In silico prediction of transcriptional factor-binding sites.
abstract: The recognition of transcription factor binding sites (TFBSs) is the first step on the way to deciphering the DNA regulatory code. A large variety of computational approaches and corresponding in silico tools for TFBS recognition are available, each having their own advantages and shortcomings. This chapter provides a brief tutorial to assist end users in the application of these tools for functional characterization of genes.
authors.affiliation: Laboratory of Theoretical Genetics, Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia. diman@bionet.nsc.ru
authors.forename: Dmitry Y
authors.initials: DY
authors.lastname: Oshchepkov
authors.forename: Victor G
authors.initials: VG
authors.lastname: Levitsky
mesh_terms: D000818:Animals; D001665:Binding Sites / Q000235:genetics; D019295:Computational Biology / Q000379:methods*; D003198:Computer Simulation; D006801:Humans; D016247:Information Storage and Retrieval; D020407:Internet; D008954:Models, Biological; D012984:Software; D014157:Transcription Factors / Q000378:metabolism*
chemical_list: D014157:Transcription Factors