title: Outcome of Endometrial Cancer Stage IIIA with Adnexa or Serosal Involvement Only.
abstract: Objective. The aim of this study is to look at possible differences in outcome between serosa and adnexal involvement stage IIIA endometrial carcinoma. Methods. 67 patients with stage IIIA endometrial carcinoma were included, 46 with adnexal involvement and 21 with serosa. A central histopathological review was performed. Results. The 7-year locoregional failure rate was (LRFR) 2.2% for adnexal involvement and 16.0% for involvement of the serosa (P = .0522). The 7-year distant metastasis-free survival was 72.7% for adnexal involvement and 58.7% for serosa (P = .3994). The 7-year disease-specific survival (DSS) was 71.8% for patients with adnexal involvement and 75.4% for patients with serosa. Conclusion. Endometrial carcinoma stage IIIA with involvement of the adnexa or serosa showed to have a comparable disease-specific survival. Locoregional control was worse for serosa involvement compared to adnexa.
authors.affiliation: Department of Radiation Oncology, Medisch Spectrum Twente, Haaksbergerstraat 55, 7513 ER Enschede, The Netherlands.
authors.forename: Jan J
authors.initials: JJ
authors.lastname: Jobsen
authors.forename: Lambert
authors.initials: L
authors.lastname: Naudin Ten Cate
authors.forename: Marnix L M
authors.initials: ML
authors.lastname: Lybeert
authors.forename: Astrid
authors.initials: A
authors.lastname: Scholten
authors.forename: Elzbieta M
authors.initials: EM
authors.lastname: van der Steen-Banasik
authors.forename: Job
authors.initials: J
authors.lastname: van der Palen
authors.forename: Marika C
authors.initials: MC
authors.lastname: Stenfert Kroese
authors.forename: Annerie
authors.initials: A
authors.lastname: Slot
authors.forename: Eltjo M J
authors.initials: EM
authors.lastname: Schutter
authors.forename: Sabine
authors.initials: S
authors.lastname: Siesling