title: Burkholderia multivorans acts as an antagonist against the growth of Burkholderia pseudomallei in soil.
abstract: In this study, it was demonstrated, by using agar diffusion tests and a Transwell system, that Burkholderia multivorans NKI379 has an antagonistic effect against the growth of B. pseudomallei. Bacterial representatives were isolated from agricultural crop soil and mixed to construct a partial bacterial community structure that was based on the results of reproducible patterns following PCR-denaturing gradient gel electrophoresis analysis of total soil chromosomes. The antagonistic effect of B. multivorans on B. pseudomallei was observed in this imitate community. In a field study of agricultural crop soil, the presence of B. pseudomallei was inversely related to the presence of the antagonistic strains B. multivorans or B. cenocepacia. B. multivorans NKI379 can survive in a broader range of pH, temperatures and salt concentrations than B. pseudomallei, suggesting that B. multivorans can adapt to extreme environmental changes and therefore predominates over B. pseudomallei in natural environments.
authors.affiliation: Department of Infectious Disease, E-DA Hospital/I-Shou University Division of Infectious Diseases, Kaohsiung, Taiwan.
authors.forename: Hsi-Hsun
authors.initials: HH
authors.lastname: Lin
authors.forename: Yao-Shen
authors.initials: YS
authors.lastname: Chen
authors.forename: Yu-Cheng
authors.initials: YC
authors.lastname: Li
authors.forename: I-Ling
authors.initials: IL
authors.lastname: Tseng
authors.forename: Tzung-Han
authors.initials: TH
authors.lastname: Hsieh
authors.forename: Leh-Miauh
authors.initials: LM
authors.lastname: Buu
authors.forename: Ya-Lei
authors.initials: YL
authors.lastname: Chen
mesh_terms: D000898:Antibiosis; D042602:Burkholderia cepacia complex / Q000502:physiology*; D016957:Burkholderia pseudomallei / Q000254:growth & development*; D006863:Hydrogen-Ion Concentration; D012492:Salts / Q000378:metabolism; D012988:Soil Microbiology; D013696:Temperature
chemical_list: D012492:Salts