title: Why are there significant differences in published narrowband ultraviolet B dosimetry recommendations? The need for national standardization of phototherapy treatment.
abstract: Narrowband ultraviolet B phototherapy is an important treatment option for psoriasis and other skin diseases. When narrowband ultraviolet B phototherapy is initiated, one method involves determining the minimal erythema dose for each patient with the starting dose at 50% to 70% of the minimal erythema dose. An alternative method involves using the recommended narrowband ultraviolet B exposure dose based on a patient's Fitzpatrick skin type. When the recommended narrowband ultraviolet B exposure doses of separate publications are compared, alarming differences are found. These discrepancies not only create confusion but also suggest the risk of phototoxicity, or its opposite, namely the risk of suboptimal dosimetry. For these reasons, this article discusses possible explanations for the wide variation in dosimetry recommendations. To remedy the current situation, the authors advocate a national standard for the practice of phototherapy treatment with the guidelines of the United Kingdom as a possible model for emulation.
authors.affiliation: New York Medical College, Valhalla, New York. Electronic address: madelainehaddican@gmail.com.
authors.forename: Madelaine M
authors.initials: MM
authors.lastname: Haddican
authors.affiliation: University of California-San Francisco, California.
authors.forename: Tina
authors.initials: T
authors.lastname: Bhutani
authors.affiliation: University of California-San Francisco, California.
authors.forename: Patricia B
authors.initials: PB
authors.lastname: McClelland
authors.affiliation: University of California-San Francisco, California.
authors.forename: John Y M
authors.initials: JYM
authors.lastname: Koo
mesh_terms: D004307:Dose-Response Relationship, Radiation; D006801:Humans; D020380:Needs Assessment; D010789:Phototherapy / Q000592:standards*; D017410:Practice Guidelines as Topic / Q000592:standards*; D011874:Radiometry / Q000592:standards*; D011879:Radiotherapy Dosage; D012871:Skin Diseases / Q000532:radiotherapy; D014467:Ultraviolet Therapy / Q000592:standards*; D006113:United Kingdom