title: Biocatalytic resolution of enantiomeric mixtures of 1-aminoethanephosphonic acid.
abstract: Several fungal strains, namely Bauveria bassiana, Cuninghamella echinulata, Aspergillus fumigatus, Penicillium crustosum and Cladosporium herbarum, were used as biocatalysts to resolve racemic mixtures of 1-aminoethanephosphonic acid using L/D amino acid oxidase activity. The course of reaction was analyzed by 31P-NMR in the presence of cyclodextrin used as chiral discriminating agent. The best result (42% e.e of R-isomer) was obtained with a strain of Cuninghamella echinulata.
authors.affiliation: Department of Bioorganic Chemistry, Faculty of Chemistry, Wroclaw University of Technology, Wybrzeże Wyspiańskiego 27, 50-370 Wroclaw, Poland. malgorzata.brzezinska-rodak@pwr.wroc.pl
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Brzezińska-Rodak
authors.forename: Magdalena
authors.initials: M
authors.lastname: Klimek-Ochab
authors.forename: Ewa
authors.initials: E
authors.lastname: Zymańczyk-Duda
authors.forename: Paweł
authors.initials: P
authors.lastname: Kafarski
mesh_terms: D001232:Aspergillus fumigatus / Q000378:metabolism; D055162:Biocatalysis; D002963:Cladosporium / Q000378:metabolism; D005658:Fungi / Q000378:metabolism*; D009682:Magnetic Resonance Spectroscopy; D063065:Organophosphonates / Q000737:chemistry* / Q000378:metabolism*; D010407:Penicillium / Q000378:metabolism; D013237:Stereoisomerism
chemical_list: D063065:Organophosphonates