title: Community transmission in the United States of a CTX-M-15-producing sequence type ST131 Escherichia coli strain resulting in death.
abstract: A middle-aged woman developed fatal urosepsis due to a multidrug-resistant Escherichia coli strain representing sequence type ST131, a recently emerged, disseminated, multidrug-resistant extraintestinal pathogen, after presumably having acquired it from her extensively antibiotic-exposed sister with chronic recurrent cystitis. Susceptibility results (reported on day 4) showed resistance to the initially selected regimen.
authors.affiliation: Division of Infectious Diseases, Department of Medicine, Maine Medical Center, Portland, Maine, USA.
authors.forename: Robert C
authors.initials: RC
authors.lastname: Owens
authors.forename: James R
authors.initials: JR
authors.lastname: Johnson
authors.forename: Patricia
authors.initials: P
authors.lastname: Stogsdill
authors.forename: Lonny
authors.initials: L
authors.lastname: Yarmus
authors.forename: Karen
authors.initials: K
authors.lastname: Lolans
authors.forename: John
authors.initials: J
authors.lastname: Quinn
mesh_terms: D016000:Cluster Analysis; D017714:Community-Acquired Infections / Q000175:diagnosis* / Q000382:microbiology / Q000635:transmission; D004269:DNA, Bacterial / Q000235:genetics; D024901:Drug Resistance, Multiple, Bacterial; D016521:Electrophoresis, Gel, Pulsed-Field; D004926:Escherichia coli / Q000145:classification / Q000187:drug effects / Q000201:enzymology* / Q000302:isolation & purification*; D004927:Escherichia coli Infections / Q000175:diagnosis* / Q000382:microbiology / Q000635:transmission; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008875:Middle Aged; D058889:Molecular Typing; D018805:Sepsis / Q000175:diagnosis* / Q000382:microbiology / Q000635:transmission; D014481:United States; D014552:Urinary Tract Infections / Q000175:diagnosis* / Q000382:microbiology / Q000635:transmission; D001618:beta-Lactamases / Q000378:metabolism*
chemical_list: D004269:DNA, Bacterial; C473109:beta-lactamase CTX-M-15; D001618:beta-Lactamases