title: [Rehabilitation by hollow obturator prosthesis immediately after total maxillectomy for malignant tumor].
abstract: OBJECTIVE
  The feasibility and clinical effects of hollow obturator prosthesis for the repair of maxillofacial defect immediately after maxillectomy for cancer were assessed.
  
  
  METHODS
  Thirteen patients with T3-4aN0M0 maxillary neoplasm were treated by the prostheses immediately after maxillectomy. According to the 3D-CT reconstruction of nasal sinus, the 3D stereoscopic prototype was constructed before the surgery. Simulating surgery with Surgicare 5.0 software and then the prosthesis 3D stereoscopic model was shaped. The prosthesis was made quickly and precisely with methacrylate resins according to the model and the print mold before surgery, with supplementary tooth at the bottom of prosthesis. In the surgery, the prosthesis was installed instantly after maxillectomy. The patients were followed up at 1, 3 and 6 month after the surgery, respectively. The facial features and the pronunciation clarity were examined and the questionnaires were carried out in the patients, with comparation by paired t-test. The hollow obturator prosthesis would be replaced by permanent prosthesis made of methacrylate resins at 6 month after the surgery.
  
  
  RESULTS
  The hollow obturator prostheses were installed accurately and maxillofacial defects were repaired immediately after maxillectomy in the 13 patients. Postoperative follow-up showed there were significant differences in eyeball sagging (t = 4.67, P < 0.05), mid-facial region collapse (t = 5.67, P < 0.05), and pronunciation clarity (t = 16.38, P < 0.05) between patients with and without prostheses. Questionnaires showed that all the patients were satisfied with the retention of prostheses, the improvement of appearance, the improvement of the symptom of water choking and speech definition. Six months after the surgery, the hollow obturator prostheses were replaced smoothly by permanent prostheses in 11 of the 13 patients.
  
  
  CONCLUSIONS
  The precise and instant repair of maxillofacial defect by prosthesis after maxillectomy can improve survival quality of patient.
authors.affiliation: Department of Otorhinolaryngology Head and Neck Surgery, the First Hospital of China Medical University, Shenyang 110001, China.
authors.forename: Xiao-ye
authors.initials: XY
authors.lastname: Li
authors.forename: Ai-hui
authors.initials: AH
authors.lastname: Yan
authors.forename: Shuai
authors.initials: S
authors.lastname: Hao
authors.forename: Wei
authors.initials: W
authors.lastname: Li
authors.forename: Xue-jun
authors.initials: XJ
authors.lastname: Jiang
authors.forename: Li
authors.initials: L
authors.lastname: Lu
authors.forename: Xing-jun
authors.initials: XJ
authors.lastname: Qin
authors.forename: Hai-xin
authors.initials: HX
authors.lastname: Yan
mesh_terms: D000328:Adult; D000368:Aged; D003831:Denture, Partial, Immediate; D005260:Female; D006801:Humans; D008297:Male; D008441:Maxillary Neoplasms / Q000601:surgery*; D019931:Maxillofacial Prosthesis Implantation; D008875:Middle Aged; D019919:Prosthesis Implantation; D019651:Plastic Surgery Procedures / Q000295:instrumentation / Q000379:methods*