title: Multiple symmetric lipomatosis.
abstract: BACKGROUND
  Multiple symmetric lipomatosis (MSL) is a relatively uncommon entity of unknown etiology characterized by symmetrically subcutaneous accumulation of nonencapsulated adipose tissue. Approximately 200 to 300 cases have been published.
  
  
  OBJECTIVE
  The aims of this article are to report the case of a 58-year-old Brazilian patient with MSL and provide a comprehensive overview of the current concepts concerning this disease.
  
  
  METHODS
  Our search yielded 28 articles on MSL, including case reports and reviews of the literature.
  
  
  RESULTS
  MSL predominantly affects Mediterranean males with a history of chronic alcohol abuse. It is usually asymptomatic and may be associated with diabetes mellitus, hyperlipidemia, hyperuricemia, macrocytic anemia, and oral cancer. Surgical resection is the best treatment option.
  
  
  CONCLUSIONS
  The case reported is a classic presentation of MSL; however, it is particularly uncommon owing to the association with immune thrombocytopenic purpura. This association has been described only once in the medical literature.
authors.affiliation: Federal University of Minas Gerais, Belo Horizonte/MG, Brazil. rodrigogsilva@uol.com
authors.forename: Rodrigo
authors.initials: R
authors.lastname: Gomes da Silva
authors.forename: Renan
authors.initials: R
authors.lastname: Detoffol Bragança
authors.forename: Carolina
authors.initials: C
authors.lastname: Ribeiro Costa
authors.forename: Lorena
authors.initials: L
authors.lastname: Torres de Melo
authors.forename: Rosa
authors.initials: R
authors.lastname: Weiss Telles
authors.forename: Luciana
authors.initials: L
authors.lastname: Costa Silva
mesh_terms: D006801:Humans; D008069:Lipomatosis, Multiple Symmetrical / Q000150:complications / Q000175:diagnosis* / Q000276:immunology; D008297:Male; D008875:Middle Aged; D011696:Purpura, Thrombocytopenic / Q000150:complications / Q000276:immunology; D012307:Risk Factors; D014057:Tomography, X-Ray Computed