title: Oxalic acid under adhesive restorations as a means to reduce dentin sensitivity: a four-month clinical trial.
abstract: The aim of this double-blind randomized controlled clinical trial was to evaluate the reduction of dentin sensitivity using an oxalate-based compound, placed under adhesive restorations, during a four-month period. One hundred three preoperatively sensitive teeth, on 36 patients aged 25-66 years (mean, 40.3±7), were included in the study. Group A (experimental) was treated with oxalic acid (BisBlock) before resin-based composite (RBC) restorations (n=52), and group B (control) was treated with distilled water before RBC restorations (n=51). The first tooth in each patient was randomly assigned to group A, and the second tooth received group B. Clinical evaluation as made by a thermal/evaporation test with an air syringe and measurement by visual analog scale (VAS) at baseline and four months after treatment. The results showed sensitivity reduction during the evaluation period (expressed in VAS values): group A, 7.6 to 0.8; group B, 7.3 to 2.6. We concluded from this study that both treatments reduced dentin sensitivity during the evaluation period, with group A showing significantly less dentin sensitivity after four months (p<0.05).
authors.affiliation: University of Chile, Operative Dentistry, Santiago, Chile.
authors.forename: Claudia
authors.initials: C
authors.lastname: Barrientos
authors.forename: Gloria
authors.initials: G
authors.lastname: Xaus
authors.forename: Catherine
authors.initials: C
authors.lastname: Leighton
authors.forename: Javier
authors.initials: J
authors.lastname: Martin
authors.forename: Valeria V
authors.initials: VV
authors.lastname: Gordan
authors.forename: Gustavo
authors.initials: G
authors.lastname: Moncada
mesh_terms: D000328:Adult; D000368:Aged; D003188:Composite Resins / Q000737:chemistry; D003764:Dental Materials / Q000737:chemistry; D003793:Dental Restoration, Permanent; D057133:Dentin Desensitizing Agents / Q000627:therapeutic use*; D003807:Dentin Sensitivity / Q000145:classification / Q000517:prevention & control*; D004311:Double-Blind Method; D005500:Follow-Up Studies; D006801:Humans; D008875:Middle Aged; D019815:Oxalic Acid / Q000627:therapeutic use*; D010147:Pain Measurement; D019163:Reducing Agents / Q000627:therapeutic use*
chemical_list: C514542:BisBlock; D003188:Composite Resins; D003764:Dental Materials; D057133:Dentin Desensitizing Agents; D019163:Reducing Agents; D019815:Oxalic Acid