title: [A case of advanced gastric cancer with tumor embolus in the portal vein successfully treated with S-1 and CDDP therapy].
abstract: A 50-year-old man with advanced gastric cancer and a tumor embolus in the portal vein was referred to our hospital. We diagnosed the tumor as cStage III B (cT3, cN2, cH0, P0, M0) gastric cancer, and selected neoadjuvant S-1 (80 mg/m2) and CDDP (60 mg/m2) therapy for him. After 2 courses of chemotherapy, the embolus in the portal vein disappeared. After additional chemotherapy, the primary tumor and regional lymph node revealed a partial response (PR), and judging from the results from the barium meal study, upper GI endoscopic findings and CT scan, a total gastrectomy with lymph node dissection was performed.
authors.affiliation: Dept. of Surgery, Fukui Prefectural Hospital, Japan.
authors.forename: Yoshihide
authors.initials: Y
authors.lastname: Asaumi
authors.forename: Tamon
authors.initials: T
authors.lastname: Miyanaga
authors.forename: Homare
authors.initials: H
authors.lastname: Ito
authors.forename: Hisato
authors.initials: H
authors.lastname: Shin
authors.forename: Manami
authors.initials: M
authors.lastname: Fujita
authors.forename: Manami
authors.initials: M
authors.lastname: Miyazaki
authors.forename: Daisuke
authors.initials: D
authors.lastname: Yagi
authors.forename: Hirotaka
authors.initials: H
authors.lastname: Kitamura
authors.forename: Mitsuyasu
authors.initials: M
authors.lastname: Hirano
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Hayashida
authors.forename: Kazuya
authors.initials: K
authors.lastname: Maeda
authors.forename: Koji
authors.initials: K
authors.lastname: Ohta
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Hayashi
authors.forename: Kenji
authors.initials: K
authors.lastname: Doden
authors.forename: Masakazu
authors.initials: M
authors.lastname: Hattori
authors.forename: Yasuo
authors.initials: Y
authors.lastname: Hashizume
authors.forename: Yasuharu
authors.initials: Y
authors.lastname: Kaizaki
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002945:Cisplatin / Q000008:administration & dosage / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D004338:Drug Combinations; D004617:Embolism / Q000188:drug therapy* / Q000209:etiology; D006801:Humans; D008297:Male; D009367:Neoplasm Staging; D010094:Oxonic Acid / Q000008:administration & dosage / Q000627:therapeutic use*; D011169:Portal Vein / Q000473:pathology*; D013274:Stomach Neoplasms / Q000098:blood supply / Q000150:complications / Q000188:drug therapy* / Q000601:surgery; D005641:Tegafur / Q000008:administration & dosage / Q000627:therapeutic use*; D014057:Tomography, X-Ray Computed
chemical_list: D004338:Drug Combinations; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid; D002945:Cisplatin