title: Regional cortical thickness and cognitive functions in non-demented Parkinson's disease patients: a pilot study.
abstract: OBJECTIVE
  The pathology of neuropsychological deficits in Parkinson's disease (PD) is incompletely defined.
  
  
  METHODS
  We investigated cortical thickness and neuropsychological performances in non-demented patients with PD and healthy controls.
  
  
  RESULTS
  Patients showed significant cortical thinning in right middle temporal and left fusiform cortices. Verbal memory performance was related with left fusiform thinning.
  
  
  CONCLUSIONS
  Cognitive and cortical changes in non-demented patients with PD are detectable and clearly related.
authors.affiliation: Movement Disorder Unit, Sant'Andrea Hospital, Rome, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Pellicano
authors.forename: F
authors.initials: F
authors.lastname: Assogna
authors.forename: F
authors.initials: F
authors.lastname: Piras
authors.forename: C
authors.initials: C
authors.lastname: Caltagirone
authors.forename: F E
authors.initials: FE
authors.lastname: Pontieri
authors.forename: G
authors.initials: G
authors.lastname: Spalletta
mesh_terms: D000328:Adult; D000368:Aged; D002540:Cerebral Cortex / Q000473:pathology*; D003071:Cognition / Q000502:physiology; D003072:Cognition Disorders / Q000473:pathology; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D010300:Parkinson Disease / Q000473:pathology* / Q000523:psychology*; D010865:Pilot Projects