title: Microvascular decompression: salient surgical principles and technical nuances.
abstract: Trigeminal neuralgia is a disorder associated with severe episodes of lancinating pain in the distribution of the trigeminal nerve. Previous reports indicate that 80-90% of cases are related to compression of the trigeminal nerve by an adjacent vessel. The majority of patients with trigeminal neuralgia eventually require surgical management in order to achieve remission of symptoms. Surgical options for management include ablative procedures (e.g., radiosurgery, percutaneous radiofrequency lesioning, balloon compression, glycerol rhizolysis, etc.) and microvascular decompression. Ablative procedures fail to address the root cause of the disorder and are less effective at preventing recurrence of symptoms over the long term than microvascular decompression. However, microvascular decompression is inherently more invasive than ablative procedures and is associated with increased surgical risks. Previous studies have demonstrated a correlation between surgeon experience and patient outcome in microvascular decompression. In this series of 59 patients operated on by two neurosurgeons (JSN and PEK) since 2006, 93% of patients demonstrated substantial improvement in their trigeminal neuralgia following the procedure--with follow-up ranging from 6 weeks to 2 years. Moreover, 41 of 66 patients (approximately 64%) have been entirely pain-free following the operation. In this publication, video format is utilized to review the microsurgical pathology of this disorder. Steps of the operative procedure are reviewed and salient principles and technical nuances useful in minimizing complications and maximizing efficacy are discussed.
authors.affiliation: Department of Neurosurgery, Vanderbilt University Medical Center. jonathan.forbes@vanderbilt.edu
authors.forename: Jonathan
authors.initials: J
authors.lastname: Forbes
authors.forename: Calvin
authors.initials: C
authors.lastname: Cooper
authors.forename: Walter
authors.initials: W
authors.lastname: Jermakowicz
authors.forename: Joseph
authors.initials: J
authors.lastname: Neimat
authors.forename: Peter
authors.initials: P
authors.lastname: Konrad
mesh_terms: D002531:Cerebellum / Q000098:blood supply; D002536:Cerebral Arteries / Q000601:surgery; D003399:Craniotomy / Q000379:methods; D005260:Female; D006801:Humans; D008297:Male; D008866:Microsurgery / Q000379:methods; D061145:Microvascular Decompression Surgery / Q000379:methods*; D014276:Trigeminal Nerve / Q000601:surgery; D014277:Trigeminal Neuralgia / Q000601:surgery*