title: Fabrication of nano-structured SPR chip for sensitivity enhancement.
abstract: We used the Langmuir-Blodgett (LB) method for preparation of large area, defect-free monolayer silica particle film as a template for the fabrication of nano-structure Au pattern on a conventional Au substrate for Surface Plasmon Resonance (SPR). Well organized, trigonal pyramid shaped Au nano-structures were able to construct on 34 separate chips in one fabrication process. The dimensions of trigonal pyramid nano-structures were precisely controlled by changing the particle size of the silica LB template. The nano-structure Au patterned SPR chips provides the enhancement of sensitivity in SPR analysis. The sensitivity enhancement of nano-structure patterned chips was evaluated by comparison with conventional flat Au chips. The nano-structure patterned substrate demonstrated a sensitivity enhancement up to 120% compared to a conventional SPR chip when ethanol solution was used as an analyte.
authors.affiliation: Department of Molecular Science and Technology, Ajou University, Suwon 443-749, Korea.
authors.forename: Hyo-Sop
authors.initials: HS
authors.lastname: Kim
authors.forename: Jin-Ho
authors.initials: JH
authors.lastname: Kim
authors.forename: Young A
authors.initials: YA
authors.lastname: Song
authors.forename: Sung-Wook
authors.initials: SW
authors.lastname: Choi
authors.forename: Yong-Jin
authors.initials: YJ
authors.lastname: Cho
authors.forename: Jae-Ho
authors.initials: JH
authors.lastname: Kim