title: A case study: neuroleptic malignant syndrome with risperidone and CYP2D6 gene variation.
abstract: We present a schizophrenic patient who experienced neuroleptic malignant syndrome with risperidone treatment due to variants of the CYP2D6 gene with reduced function. Clinicians need to be aware of this potential complication.
authors.affiliation: Department of Neuropsychiatry, Ehime University Graduate School of Medicine, Shitsukawa, Toon, Ehime 791-0295, Japan. sugekoma80@hotmail.com
authors.forename: Shinichiro
authors.initials: S
authors.lastname: Ochi
authors.forename: Koichiro
authors.initials: K
authors.lastname: Kawasoe
authors.forename: Masao
authors.initials: M
authors.lastname: Abe
authors.forename: Ryuji
authors.initials: R
authors.lastname: Fukuhara
authors.forename: Kantaro
authors.initials: K
authors.lastname: Sonobe
authors.forename: Kentaro
authors.initials: K
authors.lastname: Kawabe
authors.forename: Shu-ichi
authors.initials: S
authors.lastname: Ueno
mesh_terms: D000328:Adult; D000483:Alleles; D014150:Antipsychotic Agents / Q000009:adverse effects* / Q000378:metabolism; D019389:Cytochrome P-450 CYP2D6 / Q000235:genetics*; D005260:Female; D006801:Humans; D009459:Neuroleptic Malignant Syndrome / Q000209:etiology / Q000235:genetics*; D011110:Polymorphism, Genetic / Q000235:genetics; D018967:Risperidone / Q000009:adverse effects* / Q000378:metabolism
chemical_list: D014150:Antipsychotic Agents; D019389:Cytochrome P-450 CYP2D6; D018967:Risperidone