title: Invasive Streptococcus pneumoniae in children, Malawi, 2004-2006.
abstract: Of 176 invasive Streptococcus pneumoniae isolates from children in Malawi, common serotypes were 1 (23%), 6A/B (18%), 14 (6%), and 23F (6%). Coverage with the 7-valent pneumococcal conjugate vaccine (PCV) was 39%; PCV10 and PCV13 increased coverage to 66% and 88%, respectively. We found chloramphenicol resistance in 27% of isolates and penicillin nonsusceptibility in 10% (by using meningitis breakpoints); all were ceftriaxone susceptible.
authors.affiliation: Malawi-Liverpool-Wellcome Trust Clinical Research Programme, Blantyre, Malawi. j.cornick@liverpool.ac.uk
authors.forename: Jennifer E
authors.initials: JE
authors.lastname: Cornick
authors.forename: Dean B
authors.initials: DB
authors.lastname: Everett
authors.forename: Caroline
authors.initials: C
authors.lastname: Broughton
authors.forename: Brigitte B
authors.initials: BB
authors.lastname: Denis
authors.forename: Daniel L
authors.initials: DL
authors.lastname: Banda
authors.forename: Enitan D
authors.initials: ED
authors.lastname: Carrol
authors.forename: Christopher M
authors.initials: CM
authors.lastname: Parry
mesh_terms: D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D002648:Child; D002675:Child, Preschool; D024881:Drug Resistance, Bacterial; D005260:Female; D015658:HIV Infections / Q000150:complications; D006801:Humans; D007223:Infant; D008297:Male; D008826:Microbial Sensitivity Tests; D011008:Pneumococcal Infections / Q000175:diagnosis / Q000382:microbiology* / Q000401:mortality; D012703:Serotyping; D013296:Streptococcus pneumoniae / Q000145:classification / Q000187:drug effects / Q000302:isolation & purification / Q000502:physiology*
chemical_list: D000900:Anti-Bacterial Agents