title: Neurological complications following treatment of children with brain tumors.
abstract: Brain tumors and their treatments in children result in a range of neurological complications that can affect daily function and rehabilitation potential, including neurocognitive sequelae, ototoxicity, seizure disorders, stroke, and peripheral neuropathy. Deficits in cognitive function, particularly learning and memory, attention and speed of information processing, can be debilitating. With new insights to the cellular and molecular etiology of these deficits, new therapies for cognitive decline after therapy are emerging. Management strategies for other neurological complications are also emerging.
authors.affiliation: Department of Neurology, Stanford University, Stanford, CA 94305, USA. mmonje@stanford.edu
authors.forename: Michelle
authors.initials: M
authors.lastname: Monje
authors.forename: Paul Graham
authors.initials: PG
authors.lastname: Fisher
mesh_terms: D001932:Brain Neoplasms / Q000628:therapy*; D002648:Child; D003072:Cognition Disorders / Q000453:epidemiology / Q000209:etiology*; D003131:Combined Modality Therapy / Q000009:adverse effects; D006801:Humans; D015994:Incidence; D009483:Neuropsychological Tests; D012307:Risk Factors; D020521:Stroke / Q000453:epidemiology / Q000209:etiology*; D014481:United States / Q000453:epidemiology