title: Lessons from genome-wide association studies in venous thrombosis.
abstract: From the first genome wide association studies (GWAS) conducted on age-related macular degeneration back in 2005 until now, hundreds of studies have applied this strategy to identify novel genetic loci associated with hundreds of human diseases and related quantitative risk factors. While the GWAS revolution has just started to shift towards the next generation sequencing's burst, it is important to illustrate how the genetics research in venous thrombosis has benefit from the GWAS paradigm.
authors.affiliation: INSERM, UMR_S 626, Marseille, France. pierre.morange@ap-hm.fr
authors.forename: P E
authors.initials: PE
authors.lastname: Morange
authors.forename: D A
authors.initials: DA
authors.lastname: Tregouet
mesh_terms: D020022:Genetic Predisposition to Disease; D055106:Genome-Wide Association Study; D006801:Humans; D020641:Polymorphism, Single Nucleotide; D012307:Risk Factors; D020246:Venous Thrombosis / Q000453:epidemiology / Q000235:genetics*