title: The zebrafish embryo model in toxicology and teratology, September 2–3, 2010, Karlsruhe, Germany.
abstract: The use of fish embryos is gaining popularity for research in the area of toxicology and teratology. Particularly embryos of the zebrafish offer an array of different applications ranging from regulatory testing to mechanistic research. For this reason a consortium of two research centres and a company with the support of the COST Action EuFishBiomed has organised the Workshop “The zebrafish embryo model in toxicology and teratology”, in Karlsruhe, Germany, 2nd–3rd September 2010. The workshop aimed at bringing together experts from different areas of toxicology using the (zebra)fish embryo and stimulating networking between scientists and representatives from regulatory bodies, research institutions and industry. Recent findings, presented in various platform presentations in the area of regulatory toxicity, high throughput screening, toxicogenomics, as well as environmental and human risk assessment are highlighted in this meeting report. Furthermore, the constraints and possibilities of the model as discussed at the workshop are described. A follow up-meeting was appreciated by the about 120 participants and is planned for 2012.
authors.affiliation: UFZ – Helmholtz Centre for Environmental Research, Department of Bioanalytical Ecotoxicology, Permoserstr. 15, 04318 Leipzig, Germany.
authors.forename: Wibke
authors.initials: W
authors.lastname: Busch
authors.forename: Karen
authors.initials: K
authors.lastname: Duis
authors.forename: Martina
authors.initials: M
authors.lastname: Fenske
authors.forename: Gerd
authors.initials: G
authors.lastname: Maack
authors.forename: Juliette
authors.initials: J
authors.lastname: Legler
authors.forename: Stephanie
authors.initials: S
authors.lastname: Padilla
authors.forename: Uwe
authors.initials: U
authors.lastname: Strähle
authors.forename: Hilda
authors.initials: H
authors.lastname: Witters
authors.forename: Stefan
authors.initials: S
authors.lastname: Scholz
mesh_terms: D000014:Abnormalities, Drug-Induced / Q000209:etiology* / Q000235:genetics; D000818:Animals; D004625:Embryo, Nonmammalian / Q000002:abnormalities / Q000187:drug effects* / Q000473:pathology; D018507:Gene Expression Regulation, Developmental / Q000187:drug effects; D057166:High-Throughput Screening Assays / Q000592:standards; D006801:Humans; D018570:Risk Assessment; D013723:Teratogens / Q000633:toxicity*; D018675:Toxicity Tests / Q000592:standards; D043922:Toxicogenetics; D015027:Zebrafish / Q000196:embryology* / Q000235:genetics
chemical_list: D013723:Teratogens