title: Rapid aqueous [18F]-labeling of a bodipy dye for positron emission tomography/fluorescence dual modality imaging.
abstract: We report the rapid nucleophilic [(18)F]-radiolabeling of a bodipy dye in aqueous solutions. This radiolabeled dye, whose biodistribution and clearance has been studied in mice, is stable in vivo and can be used as a positron emission tomography/fluorescence dual modality imaging agent.
authors.affiliation: Molecular Imaging Center, Department of Radiology, University of Southern California, Los Angeles 90033, USA. ziboli@usc.edu
authors.forename: Zibo
authors.initials: Z
authors.lastname: Li
authors.forename: Tzu-Pin
authors.initials: TP
authors.lastname: Lin
authors.forename: Shuanglong
authors.initials: S
authors.lastname: Liu
authors.forename: Chiun-Wei
authors.initials: CW
authors.lastname: Huang
authors.forename: Todd W
authors.initials: TW
authors.lastname: Hudnall
authors.forename: François P
authors.initials: FP
authors.lastname: Gabbaï
authors.forename: Peter S
authors.initials: PS
authors.lastname: Conti
mesh_terms: D000818:Animals; D001896:Boron Compounds / Q000737:chemistry*; D003287:Contrast Media / Q000138:chemical synthesis / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000737:chemistry*; D005462:Fluorine Radioisotopes / Q000737:chemistry; D007553:Isotope Labeling; D007668:Kidney / Q000000981:diagnostic imaging; D008099:Liver / Q000000981:diagnostic imaging; D051379:Mice; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals / Q000138:chemical synthesis / Q000737:chemistry*
chemical_list: C095489:4,4-difluoro-4-bora-3a,4a-diaza-s-indacene; D001896:Boron Compounds; D003287:Contrast Media; D005456:Fluorescent Dyes; D005462:Fluorine Radioisotopes; D019275:Radiopharmaceuticals