title: Laryngeal cancer in Egypt: quality of life measurement with different treatment modalities.
abstract: BACKGROUND
  Quality of life (QOL) reflects the need to assess the patient's overall sense of well-being. A nonrandomized, prospective longitudinal study was conducted to evaluate QOL in Egyptian patients treated for laryngeal cancer.
  
  
  METHODS
  In all, 60 newly diagnosed patients with laryngeal cancer were divided into 3 groups: surgical resection, radiotherapy, and combined therapy. The European Organization for Research and Treatment of Cancer Quality of Life Questionnaires (EORTC-QLQ) were administered to the patients at 4 points: prior to treatment, during active treatment, and at 3 and 6 months after completion of treatment.
  
  
  RESULTS
  All pretreatment scales were worse in the combined therapy group. The functional scales reached their lowest levels in all groups during active treatment. Radiotherapy group scales showed persistent slow recovery. There was striking prevalence of the financial difficulties score in all groups.
  
  
  CONCLUSIONS
  QOL measurement provides information to guide clinical decision making in patients treated for laryngeal carcinoma.
authors.affiliation: Department of Otolaryngology, Ain Shams University, Cairo, Egypt.
authors.forename: Ossama A
authors.initials: OA
authors.lastname: Hamid
authors.forename: Lobna M
authors.initials: LM
authors.lastname: El Fiky
authors.forename: Medani M
authors.initials: MM
authors.lastname: Medani
authors.forename: Ayman
authors.initials: A
authors.lastname: Abdelhady
authors.forename: Hanan H
authors.initials: HH
authors.lastname: Ali
mesh_terms: D000223:Adaptation, Psychological; D016022:Case-Control Studies; D003131:Combined Modality Therapy; D019583:Dose Fractionation, Radiation; D004534:Egypt; D005260:Female; D006801:Humans; D007822:Laryngeal Neoplasms / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery*; D007825:Laryngectomy / Q000379:methods* / Q000401:mortality; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness / Q000473:pathology; D009367:Neoplasm Staging; D011379:Prognosis; D011788:Quality of Life; D018570:Risk Assessment; D018434:Sickness Impact Profile; D012959:Socioeconomic Factors; D011795:Surveys and Questionnaires; D016896:Treatment Outcome