title: Dynamic microvascular responses with a high speed TiVi imaging system.
abstract: TiVi technology presents a high resolution, low speed methodology for imaging microcirculation. Recently, the TiVi system was adapted to produce a high speed system capable of analysing dynamic responses from human tissues at a frame rate of 30 frames per second. We present results based on this system by investigating dynamic responses such as arterial pulsations both from a controlled flow model and in vivo tissue sites. We also quantify the effects of sympathetic vasomotion, a biological effect which is evident in many tissue sites, and show that the effects of arterial pulsations and vasomotion on the resulting TiVi time traces are easily determined.
authors.affiliation: Department of Medical Physics, Royal Surrey County Hospital, Egerton Road, Guildford GU27XX, UK. jim.o'doherty@nhs.net
authors.forename: Jim
authors.initials: J
authors.lastname: O'Doherty
authors.forename: Paul M
authors.initials: PM
authors.lastname: McNamara
authors.forename: Barry W
authors.initials: BW
authors.lastname: Fitzgerald
authors.forename: Martin J
authors.initials: MJ
authors.lastname: Leahy
mesh_terms: D006801:Humans; D008833:Microcirculation; D055806:Microvessels / Q000502:physiology*; D057054:Molecular Imaging / Q000295:instrumentation / Q000379:methods*; D012815:Signal Processing, Computer-Assisted; D014664:Vasodilation; D014741:Video Recording / Q000295:instrumentation / Q000379:methods*