title: [Evaluation of a new compact prothrombin time-international normalized ratio measurement device in pediatric management].
abstract: BACKGROUND
  In a pediatric setting, the need for lifetime oral anticoagulation is increasing because of currency of extracardiac total cavo-pulmonary connection (TCPC) and pediatric valve surgery. We evaluated a new compact device "CoaguChek XS" for measuring prothrombin time-internatinal normalized ratio (PT-INR).
  
  
  METHODS
  The international normalized ratio (INR) values obtained from 71 patients (223 samples) by a CoaguChek XS were compared with those obtained by a laboratory-based coagulation analyzer.
  
  
  RESULTS
  The values from the CoaguChek XS had a significant correlation with the laboratory based results. (r2 = 0.92, p < 0.01, regression line y = 1.05 x -0.02).
  
  
  CONCLUSIONS
  The CoaguChek XS will be useful in pediatric management.
authors.affiliation: Division of Cardiovascular Surgery, Nagano Children's Hospital, Azumino, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Maekawa
authors.forename: T
authors.initials: T
authors.lastname: Sakawa
authors.forename: K
authors.initials: K
authors.lastname: Umezu
authors.forename: N
authors.initials: N
authors.lastname: Ohashi
authors.forename: Y
authors.initials: Y
authors.lastname: Harada
authors.forename: S
authors.initials: S
authors.lastname: Yasukochi
authors.forename: K
authors.initials: K
authors.lastname: Takigiku
authors.forename: H
authors.initials: H
authors.lastname: Matsui
authors.forename: N
authors.initials: N
authors.lastname: Inoue
authors.forename: Y
authors.initials: Y
authors.lastname: Morimoto
authors.forename: S
authors.initials: S
authors.lastname: Watanabe
authors.forename: H
authors.initials: H
authors.lastname: Mori
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005260:Female; D018610:Heart Bypass, Right; D006351:Heart Valves / Q000601:surgery; D006801:Humans; D007223:Infant; D008297:Male; D011517:Prothrombin Time / Q000295:instrumentation*; D055815:Young Adult