title: Trans-dimer D, a novel dimeric sesquiterpene with a bis-bisabolene skeleton from a Hainan sponge Axinyssa variabilis.
abstract: A novel bisabolene sesquiterpene dimer named trans-dimer D (1) and its diastereoisomer trans-dimer C (2) reported in our previous work have been isolated as an inseparable mixture in a ratio of 1.5:1 from the South China Sea sponge Axinyssa variabilis. The structure of 1 was determined on the basis of extensive spectroscopic analysis and by comparison of its NMR spectral data with those of structurally related compounds. Compound 1 represents the fourth example of a sesquiterpene dimer with a bis-bisabolene skeleton.
authors.affiliation: Department of Pharmacy, Nanchang University, Nanchang, China.
authors.forename: Shui-Chun
authors.initials: SC
authors.lastname: Mao
authors.forename: Yue-Wei
authors.initials: YW
authors.lastname: Guo
authors.forename: Rob
authors.initials: R
authors.lastname: van Soest
authors.forename: Guido
authors.initials: G
authors.lastname: Cimino
mesh_terms: D000818:Animals; D015394:Molecular Structure; D011161:Porifera / Q000737:chemistry*; D012717:Sesquiterpenes / Q000737:chemistry* / Q000302:isolation & purification*; D013237:Stereoisomerism
chemical_list: D012717:Sesquiterpenes; C560970:trans-dimer D, Axinyssa variabilis