title: [Application of intravenous immunoglobulin preparations (IVIGs) in organ transplantation].
abstract: In clinical setting intravenous immunoglobulin preparations (IVIGs) are used for over thirty years. They were used initially as a substitutive treatment. Discovering of IVIG immunosuppressive properties has led to its use in the treatment of autoimmune diseases. Since then the range of indications in this group of diseases is becoming wider. With regard to IVIG's multidirectional influence exerted on the immune system it has also find its application in transplantology. In the article IVIG's mechanism of action, possible applications in transplantation and adverse effects are discussed.
authors.affiliation: Klinika Immunologii, Transplantologii i Chorób Wewnetrznych, Instytut Transplantologii Warszawskiego Uniwersytetu Medycznego. gsenat@poczta.onet.pl
authors.forename: Grzegorz
authors.initials: G
authors.lastname: Senatorski
authors.forename: Ewa
authors.initials: E
authors.lastname: Hryniewiecka
mesh_terms: D006801:Humans; D056724:Immunity, Humoral; D016756:Immunoglobulins, Intravenous / Q000009:adverse effects / Q000276:immunology* / Q000627:therapeutic use*; D017053:Infection Control / Q000379:methods; D007239:Infections / Q000276:immunology; D011655:Pulmonary Embolism / Q000139:chemically induced; D014181:Transplantation Immunology / Q000276:immunology*
chemical_list: D016756:Immunoglobulins, Intravenous