title: Fusobacterium necrophorum causing infective endocarditis and liver and splenic abscesses.
abstract: A 25-year-old male without prior co-morbidities was admitted to hospital with Fusobacterium necrophorum bacteremia, where he was found to have liver and splenic abscesses. Further evaluation with echocardiography revealed a bicuspid aortic valve with severe insufficiency and a 1.68 x 0.86 cm vegetation. The patient required abscess drainage, intravenous antimicrobial therapy and aortic valve replacement. Complete resolution of the infection was achieved after valve replacement and a prolonged course of intravenous antimicrobial therapy. A brief analysis of the patient's clinical course and review of the literature is presented.
authors.affiliation: Department of Medicine, University of Nebraska Medical Center, Omaha, NE, USA.
authors.forename: Marc Zac
authors.initials: MZ
authors.lastname: Handler
authors.forename: Benjamin
authors.initials: B
authors.lastname: Miriovsky
authors.forename: Howard E
authors.initials: HE
authors.lastname: Gendelman
authors.forename: Uriel
authors.initials: U
authors.lastname: Sandkovsky
mesh_terms: D018784:Abdominal Abscess / Q000382:microbiology*; D000328:Adult; D016470:Bacteremia / Q000382:microbiology*; D004697:Endocarditis, Bacterial / Q000382:microbiology*; D005674:Fusobacterium Infections / Q000150:complications*; D005675:Fusobacterium necrophorum / Q000302:isolation & purification*; D006801:Humans; D008297:Male; D012720:Severity of Illness Index; D013158:Splenic Diseases / Q000382:microbiology*