title: Increased serum interleukin-17 levels in patients with myasthenia gravis.
abstract: It has been suggested that interleukin-17 (IL-17) plays a crucial role in the development of several autoimmune diseases. However, there are no data about the relationship between myasthenia gravis and IL-17. The aim of this study was to measure the concentration of IL-17 and determine whether levels depend on the severity of MG. Serum IL-17 concentrations were measured in 25 patients. IL-17 concentrations were higher in generalized MG compared with controls and correlated with anti-acetylcholinesterase receptor antibody titers.
authors.affiliation: Neurology Department, Miguel Servet University Hospital, Paseo Isabel la Católica, No.1-3, Zaragoza 50009, Spain. jcrochebueno@hotmail.com
authors.forename: Jose C
authors.initials: JC
authors.lastname: Roche
authors.forename: Jose L
authors.initials: JL
authors.lastname: Capablo
authors.forename: Luis
authors.initials: L
authors.lastname: Larrad
authors.forename: Javier
authors.initials: J
authors.lastname: Gervas-Arruga
authors.forename: Jose R
authors.initials: JR
authors.lastname: Ara
authors.forename: Alejandro
authors.initials: A
authors.lastname: Sánchez
authors.forename: Raquel
authors.initials: R
authors.lastname: Alarcia
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D020381:Interleukin-17 / Q000097:blood*; D015850:Interleukin-6 / Q000097:blood; D008297:Male; D008875:Middle Aged; D009157:Myasthenia Gravis / Q000097:blood*
chemical_list: D020381:Interleukin-17; D015850:Interleukin-6