title: Spectrum of diseases presenting as architectural distortion on mammography: multimodality radiologic imaging with pathologic correlation.
abstract: Architectural distortion is the third most-common appearance of breast cancer and often is a subtle finding on mammography. In this article, we review a variety of breast diseases that may present as architectural distortion on mammography; review the utility of correlative imaging, such as ultrasound and magnetic resonance; and review appropriate management for these diagnoses. Primary causes include breast cancer, ductal carcinoma in situ, radial scar, complex sclerosing lesion, and fat necrosis. Secondary etiologies include previous breast surgery, trauma, and infection. Familiarity with imaging findings presenting as distortion on multimodality imaging will optimize detection and management of this subtle-yet-significant finding.
authors.affiliation: Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA. rshaheen@bidmc.harvard.edu
authors.forename: Rola
authors.initials: R
authors.lastname: Shaheen
authors.forename: Catrien A
authors.initials: CA
authors.lastname: Schimmelpenninck
authors.forename: Lanu
authors.initials: L
authors.lastname: Stoddart
authors.forename: Howard
authors.initials: H
authors.lastname: Raymond
authors.forename: Priscilla J
authors.initials: PJ
authors.lastname: Slanetz
mesh_terms: D000328:Adult; D000368:Aged; D001940:Breast / Q000473:pathology / Q000601:surgery; D001941:Breast Diseases / Q000000981:diagnostic imaging / Q000473:pathology; D001943:Breast Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology*; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000000981:diagnostic imaging* / Q000473:pathology*; D002921:Cicatrix / Q000000981:diagnostic imaging; D005218:Fat Necrosis / Q000000981:diagnostic imaging; D005260:Female; D005348:Fibrocystic Breast Disease / Q000000981:diagnostic imaging; D006801:Humans; D016462:Mammaplasty; D008327:Mammography / Q000379:methods*; D015412:Mastectomy, Segmental; D008875:Middle Aged