title: Primary pulmonary cancer colliding with metastatic breast carcinoma: hitherto unreported cases of cancer-to-cancer metastasis focusing on clinical implications.
abstract: Lung is one of the main sites of metastatic tumors, but collision neoplasms consisting of a primary lung cancer and metastatic breast carcinoma have never been so far reported. We describe here 2 cases of primary non-small cell lung cancers (squamous cell and adenocarcinoma, respectively) colliding with metastatic breast carcinomas (ductal and lobular carcinomas, respectively). Clinico-pathologic features characterizing this challenging diagnosis and the important therapeutic implications are discussed.
authors.affiliation: Department of Oncology, Haematology and Respiratory Diseases, Azienda Ospedaliero-Universitaria Policlinico di Modena & University of Modena and Reggio Emilia, Modena, Italy.
authors.forename: Federico
authors.initials: F
authors.lastname: Piacentini
authors.forename: Giulio
authors.initials: G
authors.lastname: Rossi
authors.forename: Christian
authors.initials: C
authors.lastname: Casali
authors.forename: Annamaria
authors.initials: A
authors.lastname: Cadioli
authors.forename: Elena
authors.initials: E
authors.lastname: Barbieri
authors.forename: Valentina
authors.initials: V
authors.lastname: Guarneri
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis* / Q000473:pathology / Q000503:physiopathology / Q000628:therapy; D000368:Aged; D000818:Animals; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000503:physiopathology / Q000628:therapy; D044584:Carcinoma, Ductal / Q000175:diagnosis* / Q000503:physiopathology / Q000556:secondary / Q000628:therapy; D018275:Carcinoma, Lobular / Q000175:diagnosis* / Q000503:physiopathology / Q000556:secondary / Q000628:therapy; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis* / Q000473:pathology / Q000503:physiopathology / Q000628:therapy; D059186:Chemoradiotherapy, Adjuvant; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000503:physiopathology / Q000556:secondary*; D008408:Mastectomy; D008875:Middle Aged; D009367:Neoplasm Staging; D057089:Pathology, Molecular; D011013:Pneumonectomy; D012074:Remission Induction