title: Two new dammarane monodesmosides from Centella asiatica.
abstract: Two new dammarane monodesmosides centellosides A (1) and B (2), and two new natural products ginsenosides Mc (10) and Y (11), together with 11 known compounds (3-9 and 12-15) reported for the first time from this genus, were isolated from the whole plants of Centella asiatica. All structures were elucidated by spectroscopic techniques and chemical methods, and compared with literature values. All the isolated compounds were evaluated in vitro for cytotoxicity.
authors.affiliation: Department of Chinese Traditional Medicine, Shanghai Institute of Pharmaceutical Industry, Shanghai, China.
authors.forename: Xiao-Xiang
authors.initials: XX
authors.lastname: Weng
authors.forename: Yan
authors.initials: Y
authors.lastname: Shao
authors.forename: Yun-Yan
authors.initials: YY
authors.lastname: Chen
authors.forename: Wen
authors.initials: W
authors.lastname: Gao
authors.forename: Liang
authors.initials: L
authors.lastname: Cheng
authors.forename: De-Yun
authors.initials: DY
authors.lastname: Kong
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D028041:Centella / Q000737:chemistry*; D004354:Drug Screening Assays, Antitumor; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D036145:Ginsenosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D056945:Hep G2 Cells; D006801:Humans; D020014:K562 Cells; D015394:Molecular Structure; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D000097669:Dammaranes
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D004365:Drugs, Chinese Herbal; D036145:Ginsenosides; D006027:Glycosides; D014315:Triterpenes; D000097669:Dammaranes; C561158:centelloside A; C561159:centelloside B