title: Antifeedant diterpenoids against Tribolium castaneum from the stems and twigs of Ceriops tagal (Rhizophoraceae).
abstract: The screening of several Chinese mangrove plants for insecticidal principles showed that ethanol extract of Ceriops tagal stems and twigs possessed significant feeding deterrent activity against the red flour beetle, Tribolium castaneum (Family: Rhizophoraceae). From the ethanol extract, three feeding deterrent diterpenoids were isolated by bioassay-guided fractionation. The compounds were identified as tagalsin A, B, and H on the basis of their phytochemical and spectral data. Tagalsin A, B, and H exhibited strong feeding deterrent activity against T. castaneum adults with EC₅₀ values of 375.3 ppm, 277.3 ppm, and 285.45 ppm, respectively.
authors.affiliation: Protection and Utilization of Traditional Chinese Medicine of Beijing Area Major Laboratory, Beijing Normal University, Haidian District, Beijing 100875, China. dushushan@bnu.edu.cn
authors.forename: Shu Shan
authors.initials: SS
authors.lastname: Du
authors.forename: Cheng Fang
authors.initials: CF
authors.lastname: Wang
authors.forename: Jing
authors.initials: J
authors.lastname: Li
authors.forename: Hai Ming
authors.initials: HM
authors.lastname: Zhang
authors.forename: Qi Zhi
authors.initials: QZ
authors.lastname: Liu
authors.forename: Zhi Long
authors.initials: ZL
authors.lastname: Liu
authors.forename: Zhi Wei
authors.initials: ZW
authors.lastname: Deng
mesh_terms: D000818:Animals; D001517:Coleoptera / Q000187:drug effects*; D004224:Diterpenes / Q000737:chemistry / Q000494:pharmacology*; D007306:Insecticides / Q000737:chemistry / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010936:Plant Extracts / Q000737:chemistry* / Q000494:pharmacology*; D018547:Plant Stems / Q000737:chemistry*; D043982:Rhizophoraceae / Q000737:chemistry*; D014231:Tribolium / Q000737:chemistry*
chemical_list: D004224:Diterpenes; D007306:Insecticides; D010936:Plant Extracts