title: [The recent progress in the studies of vitamin D receptor].
abstract: Vitamin D receptor (VDR) is a nuclear receptor which can regulate the expression of many kinds of genes by combining with its ligand. This article is about the recent progress in the studies of VDR, including its co-activator, co-repressor, and the function in development, differentiation, immuno-regulation and cancer repressor. In the end, we summarized the recent progress in research of drug development about the analog of VDR ligand.
authors.affiliation: National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100005, China.
authors.forename: Jian
authors.initials: J
authors.lastname: Cui
authors.forename: Hong
authors.initials: H
authors.lastname: Chen
authors.forename: Bing-ren
authors.initials: BR
authors.lastname: Huang
mesh_terms: D000818:Animals; D005786:Gene Expression Regulation; D006801:Humans; D056747:Immunomodulation; D009369:Neoplasms / Q000503:physiopathology; D011110:Polymorphism, Genetic; D018167:Receptors, Calcitriol / Q000235:genetics* / Q000502:physiology*; D014807:Vitamin D / Q000378:metabolism
chemical_list: D018167:Receptors, Calcitriol; D014807:Vitamin D