title: Myxofibrosarcoma of the infratemporal space.
abstract: A 42-year-old lady described a three-month history of a left-sided, painless swelling below the left earlobe. She presented to us after an acute exacerbation--with complaints of aching pain over the area for the past ten days. Computed tomography (CT) revealed a heterodense mass lesion measuring 48 x 53 mm at its greatest dimension, arising from the left infratemporal fossa. A preoperative trucut biopsy of the lesion showed features of a spindle cell lesion with fibromyxoid stroma. Resection of the infratemporal mass, a left-sided posterior segmental mandibulectomy with infratemporal clearance was performed. The tumor was histopathologically and immunohistochemically diagnosed as a myxofibrosarcoma-Grade II. She received 56 Gy/30 fractions postoperatively. The patient's postoperative clinical course was uneventful, and she remains free of disease 26 months after treatment. We review our experience and to the best of our knowledge, document the first case of myxofibrosarcoma to arise in the infratemporal space.
authors.affiliation: Department of Surgical Oncology, Cancer Institute WIA, 36, Sardar Patel Road, Adyar, Chennai 600 020, India. dravindkrishnamurthy@yahoo.com
authors.forename: Arvind
authors.initials: A
authors.lastname: Krishnamurthy
authors.forename: Anitha
authors.initials: A
authors.lastname: Vaidhyanathan
authors.forename: Urmila
authors.initials: U
authors.lastname: Majhi
mesh_terms: D000328:Adult; D003037:Cobalt Radioisotopes; D003131:Combined Modality Therapy; D019583:Dose Fractionation, Radiation; D005260:Female; D005354:Fibrosarcoma / Q000000981:diagnostic imaging* / Q000473:pathology / Q000628:therapy; D006258:Head and Neck Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000628:therapy; D006801:Humans; D008339:Mandibular Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000628:therapy; D018714:Radiotherapy, Adjuvant; D013701:Temporal Bone; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D003037:Cobalt Radioisotopes