title: Subcortical low-intensity and restricted diffusion after first seizure in a child.
abstract: Our purpose was to increase the knowledge about subcortical low-intensity images on long repetition time by describing brain magnetic resonance images of a young boy after his first spontaneous seizure. Evident in the epileptogenic area were transient images of reversible subcortical low intensity on long-repetition time, T2*-weighted, and b = 0 s/mm2 diffusion, isointense signal on b = 1000 s/mm2 diffusion, and restricted diffusion. Most likely, mechanism was axonal flow disruption with iron accumulation and free radicals production induced during seizure.
authors.affiliation: Unit NINT Neuroimaging and Neurointervention, Azienda Ospedaliera Universitaria Senese, Policlinico Santa Maria alle Scotte, Siena, Italy. alfonsocerase@aliceposta.it
authors.forename: Alfonso
authors.initials: A
authors.lastname: Cerase
authors.forename: Sara
authors.initials: S
authors.lastname: Leonini
authors.forename: Rossella
authors.initials: R
authors.lastname: Franceschini
authors.forename: Salvatore
authors.initials: S
authors.lastname: Grosso
authors.forename: Carlo
authors.initials: C
authors.lastname: Venturi
mesh_terms: D001921:Brain / Q000473:pathology*; D002648:Child; D003287:Contrast Media; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods*; D004569:Electroencephalography; D006801:Humans; D008297:Male; D012640:Seizures / Q000473:pathology*
chemical_list: D003287:Contrast Media