title: Copper-mediated trifluoromethylation of arylboronic acids by trifluoromethyl sulfonium salts.
abstract: The ligand-free trifluoromethylation of arylboronic acids with a [Ph(2)SCF(3)](+)[OTf](-)/Cu(0) system has been carefully investigated. Aryl-, alkenyl- and heteroarylboronic acids with a variety of functional groups were suitable substrates for this reaction. It is suggested that a CuCF(3) species is formed under the reaction conditions.
authors.affiliation: Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, China.
authors.forename: Cheng-Pan
authors.initials: CP
authors.lastname: Zhang
authors.forename: Ji
authors.initials: J
authors.lastname: Cai
authors.forename: Chang-Bing
authors.initials: CB
authors.lastname: Zhou
authors.forename: Xiao-Ping
authors.initials: XP
authors.lastname: Wang
authors.forename: Xing
authors.initials: X
authors.lastname: Zheng
authors.forename: Yu-Cheng
authors.initials: YC
authors.lastname: Gu
authors.forename: Ji-Chang
authors.initials: JC
authors.lastname: Xiao
mesh_terms: D001897:Boronic Acids / Q000737:chemistry*; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D012492:Salts / Q000737:chemistry; D013452:Sulfonium Compounds / Q000737:chemistry*
chemical_list: D001897:Boronic Acids; D012492:Salts; D013452:Sulfonium Compounds; D003300:Copper