title: Superselective internal radiation with yttrium-90 microspheres in the management of a chemorefractory testicular liver metastasis.
abstract: We treated a patient with biopsy-proven, chemotherapy-resistant testicular cancer liver metastasis using Y-90 selective internal radiation treatment. We chose yttrium-90 rather than surgery and ablation due to tumor location and size as well as the patient's clinical history. The result was marked tumor response by positron emission tomography and computed tomography as well as significant improvement of the patient's quality of life accompanied by a substantial decrease of his tumor markers.
authors.affiliation: Memorial Sloan Kettering Cancer Center, 410, E68th Street, New York, NY 10065, USA.
authors.forename: Panagiotis A
authors.initials: PA
authors.lastname: Sideras
authors.forename: Constantinos T
authors.initials: CT
authors.lastname: Sofocleous
authors.forename: Lynn A
authors.initials: LA
authors.lastname: Brody
authors.forename: Robert H
authors.initials: RH
authors.lastname: Siegelbaum
authors.forename: Rajesh P
authors.initials: RP
authors.lastname: Shah
authors.forename: Neeta-Pandit
authors.initials: NP
authors.lastname: Taskar
mesh_terms: D014408:Biomarkers, Tumor / Q000097:blood; D019008:Drug Resistance, Neoplasm; D006801:Humans; D008113:Liver Neoplasms / Q000097:blood / Q000175:diagnosis / Q000532:radiotherapy* / Q000556:secondary*; D008297:Male; D008863:Microspheres; D008875:Middle Aged; D011788:Quality of Life; D012074:Remission Induction; D013736:Testicular Neoplasms / Q000473:pathology*; D015021:Yttrium Radioisotopes / Q000008:administration & dosage*
chemical_list: D014408:Biomarkers, Tumor; D015021:Yttrium Radioisotopes