title: [Bilateral conjunctival oedema as a symptom of adrenal adenocarcinoma].
abstract: METHODS
  We present a case of a 67-year-old female suffering for bilateral conjunctival oedema that did not improve with antibiotic and antiinflammatory treatment. After a complete systemic examination she was diagnosed with an adrenal adenocarcinoma and treated by surgery and chemotherapy. The conjunctival chemosis subsequently improved. Unfortunately the patient died of respiratory failure due to metastasis.
  
  
  CONCLUSIONS
  We emphasise the need of an exhaustive and complete examination by the ophthalmologist in cases of non-responders to topical antibiotic and antiinflammatory treatment in patients with bilateral conjunctival oedema, in order to make a correct diagnosis of systemic potentially lethal diseases.
authors.affiliation: Departamento de Oftalmología, Hospital Universitario Príncipe de Asturias, Universidad de Alcalá, Madrid, España. javier paz moreno@hotmail.com
authors.forename: J
authors.initials: J
authors.lastname: Paz Moreno-Arrones
authors.forename: M Á
authors.initials: MÁ
authors.lastname: Montes-Mollón
mesh_terms: D000230:Adenocarcinoma / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy / Q000556:secondary / Q000601:surgery; D000306:Adrenal Cortex Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy / Q000601:surgery; D000315:Adrenalectomy; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002945:Cisplatin / Q000008:administration & dosage; D003131:Combined Modality Therapy; D003229:Conjunctival Diseases / Q000175:diagnosis / Q000209:etiology*; D003480:Cushing Syndrome / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology* / Q000601:surgery; D003520:Cyclophosphamide / Q000008:administration & dosage; D003924:Diabetes Mellitus, Type 2 / Q000150:complications; D004317:Doxorubicin / Q000008:administration & dosage; D004487:Edema / Q000175:diagnosis / Q000209:etiology*; D005047:Etoposide / Q000008:administration & dosage; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000378:metabolism; D007654:Ketoconazole / Q000627:therapeutic use; D008175:Lung Neoplasms / Q000556:secondary; D009364:Neoplasm Recurrence, Local; D010257:Paraneoplastic Syndromes / Q000175:diagnosis / Q000209:etiology*; D012131:Respiratory Insufficiency / Q000209:etiology; D014750:Vincristine / Q000008:administration & dosage
chemical_list: D014750:Vincristine; D005047:Etoposide; D004317:Doxorubicin; D003520:Cyclophosphamide; D002945:Cisplatin; D007654:Ketoconazole; D006854:Hydrocortisone