title: Chemiluminescence of the reaction system Ce(IV)-non-steroidal anti-inflammatory drugs containing europium(III) ions and its application to the determination of naproxen in pharmaceutical preparations and urine.
abstract: The chemiluminescence (CL) of oxidation of non-steroidal anti-inflammatory drugs (NSAIDs) by Ce(IV) ions, was recorded in the presence and absence europium(III) ions, in solution of pH ~ 4 of solution. Kinetic curves and CL emission spectra of the all studied systems were discussed. CL of measurable intensity was observed in the Ce(IV)-NP-Eu(III) reaction system only in acidic solutions. The CL spectrum rcegistered for this system shows emission bands, typical of Eu(III) ions, with maximum at λ ~ 600 nm. The chemiluminescent method, based on Eu(III) emission in reaction system of NP-Ce(IV)-Eu(III) in acid solution was therefore used for the determination of naproxen in mixture of non-steroidal anti-inflammatory drugs.
authors.affiliation: Department of Rare Earths, Faculty of Chemistry, Adam Mickiewicz University, Poznań, Poland. mkaczmar@amu.edu.pl
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Kaczmarek
mesh_terms: D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000737:chemistry*; D002563:Cerium / Q000737:chemistry*; D005063:Europium / Q000737:chemistry*; D006801:Humans; D007477:Ions / Q000737:chemistry; D049449:Luminescence; D009288:Naproxen / Q000032:analysis*; D009942:Organometallic Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D004364:Pharmaceutical Preparations / Q000032:analysis*; D012016:Reference Values
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D007477:Ions; D009942:Organometallic Compounds; D004364:Pharmaceutical Preparations; D002563:Cerium; D005063:Europium; D009288:Naproxen