title: Non-insulinoma pancreatogenous hypoglycemia syndrome.
abstract: We present the case of a 55 yr female who had recurrent severe hypoglycemic attacks with neuroglycopenic symptoms and altered sensorium including coma. The hypoglycemic episodes were not related to fasting. The hypoglycemia was hyperinsulinemic but all imaging modalities for insulinoma were negative. Selective arterial calcium stimulation test localized the lesion to splenic artery territory and distal pancreatectomy left to the splenic vein was done. The histopathology was consistent with nesidioblastosis and gradient guided pancreatectomy relieved the hypoglycemic episodes.
authors.affiliation: Department of Endocrinology, Batra Hospital and Medical Research Center, New Delhi.
authors.forename: Chander Mohan
authors.initials: CM
authors.lastname: Batra
authors.forename: Sundeep Singh
authors.initials: SS
authors.lastname: Saluja
authors.forename: Rajeev
authors.initials: R
authors.lastname: Bajaj
authors.forename: Usha
authors.initials: U
authors.lastname: Rajshekar
authors.forename: Vineeta
authors.initials: V
authors.lastname: Thakur
authors.forename: Vimal
authors.initials: V
authors.lastname: Gupta
mesh_terms: D001786:Blood Glucose / Q000378:metabolism; D002096:C-Peptide / Q000097:blood; D002118:Calcium / Q000097:blood; D005260:Female; D006801:Humans; D006946:Hyperinsulinism / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D007003:Hypoglycemia / Q000175:diagnosis* / Q000209:etiology / Q000601:surgery; D007004:Hypoglycemic Agents / Q000627:therapeutic use; D007150:Immunohistochemistry; D007269:Injections, Intra-Arterial; D007328:Insulin / Q000097:blood*; D007340:Insulinoma / Q000097:blood / Q000473:pathology; D008875:Middle Aged; D010180:Pancreatectomy; D010190:Pancreatic Neoplasms / Q000097:blood / Q000473:pathology; D013156:Splenectomy; D013577:Syndrome; D016896:Treatment Outcome
chemical_list: D001786:Blood Glucose; D002096:C-Peptide; D007004:Hypoglycemic Agents; D007328:Insulin; D002118:Calcium