title: Evaluation of four rapid diagnostic tests for the diagnosis of Plasmodium vivax in Korea.
abstract: OBJECTIVE
  To evaluate 4 rapid malaria diagnostic kits (RDTs) in Korea: OptiMAL test, SD BIOLINE Malaria Ag P.f/Pan test, Humasis Malaria P.f/Pan antigen test and CareStart Malaria Pf/Pv Combo test.
  
  
  METHODS
  Hundred malaria patients with Plasmodium vivax (P. vivax) and 100 healthy volunteers were recruited. The results from earlier four RDTs were compared with the reference standard, the Giemsa-stained traditional microscopic diagnosis.
  
  
  RESULTS
  Compared with the reference standard, the sensitivity and specificity for Plasmodium vivax were 92.7 and 100% for SD BIOLINE Malaria Ag P.f/Pan; and 94.6% and 100% for OptiMAL; 95.5% and 100% for both Humasis Malaria P.f/Pan antigen test and CareStart Malaria Pf/Pv Combo test.
  
  
  CONCLUSIONS
  The performances of all four malaria RDT kits were acceptable, although Humasis Malaria P.f/Pan antigen test and CareStart Malaria Pf/Pv Combo test gave superior performances with ROK isolates.
authors.affiliation: Department of Laboratory Medicine, Korea University, Seoul, Korea.
authors.forename: Kyung Hee
authors.initials: KH
authors.lastname: Kim
authors.forename: Jin Woo
authors.initials: JW
authors.lastname: Jang
authors.forename: Mi Kyung
authors.initials: MK
authors.lastname: Woo
authors.forename: Jun Seo
authors.initials: JS
authors.lastname: Oh
authors.forename: Eun Taek
authors.initials: ET
authors.lastname: Han
authors.forename: Won Ja
authors.initials: WJ
authors.lastname: Lee
authors.forename: Seong Soo A
authors.initials: SS
authors.lastname: An
authors.forename: Chae Seung
authors.initials: CS
authors.lastname: Lim
mesh_terms: D000328:Adult; D000818:Animals; D003955:Diagnostic Tests, Routine / Q000379:methods*; D006801:Humans; D016780:Malaria, Vivax / Q000175:diagnosis*; D010966:Plasmodium vivax / Q000302:isolation & purification*; D011237:Predictive Value of Tests; D011933:Reagent Kits, Diagnostic / Q000592:standards*; D056910:Republic of Korea; D012680:Sensitivity and Specificity; D055815:Young Adult
chemical_list: D011933:Reagent Kits, Diagnostic