title: Late-onset Klebsiella oxytoca flap-margin-related corneal ulcer following laser in situ keratomileusis.
abstract: A 45-year-old woman developed a spontaneous flap-margin-related corneal ulcer 11 years after the original laser in situ keratomileusis (LASIK) procedure. Two enhancements had been performed; the most recent was 3 years prior to presentation. Cultures were positive for a heavy growth of Klebsiella oxytoca. The ulcer responded clinically to topical treatment with fortified cefazolin. Eighteen days after presentation, the infiltrate had resolved and the cornea had fully epithelialized. To our knowledge, this is the first report of post-LASIK infectious keratitis caused by K oxytoca.
authors.affiliation: Department of Ophthalmology, Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada. sonia.y@gmail.com
authors.forename: Sonia N
authors.initials: SN
authors.lastname: Yeung
authors.forename: Alejandro
authors.initials: A
authors.lastname: Lichtinger
authors.forename: Peter
authors.initials: P
authors.lastname: Kim
authors.forename: Maoz D
authors.initials: MD
authors.lastname: Amiran
authors.forename: Allan R
authors.initials: AR
authors.lastname: Slomovic
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002437:Cefazolin / Q000627:therapeutic use; D019781:Corneal Topography; D003320:Corneal Ulcer / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D015818:Eye Infections, Bacterial / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D005260:Female; D006801:Humans; D020731:Keratomileusis, Laser In Situ; D007710:Klebsiella Infections / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D041121:Klebsiella oxytoca / Q000302:isolation & purification*; D008875:Middle Aged; D013524:Surgical Flaps / Q000382:microbiology*; D013530:Surgical Wound Infection / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*
chemical_list: D000900:Anti-Bacterial Agents; D002437:Cefazolin