title: Retrospective and prospective verification of the Cepheid Xpert influenza virus assay.
abstract: We performed a retrospective (n = 121) and prospective (n = 305) verification of the Cepheid Xpert Flu assay to determine its performance characteristics. The overall sensitivity and specificity were 93% and 100%, respectively. Nasopharyngeal specimen sensitivities were 100% for seasonal influenza A/H1 virus and influenza A/H3 virus, 90% for influenza A/2009/H1N1 virus, and 95% for influenza B virus.
authors.affiliation: UNC School of Medicine, Department of Pathology and Laboratory Medicine, Campus Box 7525, Chapel Hill, NC 27599-7525, USA.
authors.forename: Elena B
authors.initials: EB
authors.lastname: Popowitch
authors.forename: Elaine
authors.initials: E
authors.lastname: Rogers
authors.forename: Melissa B
authors.initials: MB
authors.lastname: Miller
mesh_terms: D006801:Humans; D009980:Influenza A virus / Q000145:classification / Q000302:isolation & purification*; D009981:Influenza B virus / Q000145:classification / Q000302:isolation & purification*; D007251:Influenza, Human / Q000175:diagnosis* / Q000821:virology*; D025202:Molecular Diagnostic Techniques / Q000379:methods*; D009305:Nasopharynx / Q000821:virology; D011446:Prospective Studies; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D014773:Virology / Q000379:methods*