title: Melioidosis, phnom penh, Cambodia.
abstract: We describe 58 adult patients with melioidosis in Cambodia (2007-2010). Diabetes was the main risk factor (59%); 67% of infections occurred during the rainy season. Bloodstream infection was present in 67% of patients, which represents 12% of all bloodstream infections. The case-fatality rate was 52% and associated with inappropriate empiric treatment.
authors.affiliation: Institute of Tropical Medicine, Antwerp, Belgium. evlieghe@itg.be
authors.forename: Erika
authors.initials: E
authors.lastname: Vlieghe
authors.forename: Lim
authors.initials: L
authors.lastname: Kruy
authors.forename: Birgit
authors.initials: B
authors.lastname: De Smet
authors.forename: Chun
authors.initials: C
authors.lastname: Kham
authors.forename: Chhun Heng
authors.initials: CH
authors.lastname: Veng
authors.forename: Thong
authors.initials: T
authors.lastname: Phe
authors.forename: Olivier
authors.initials: O
authors.lastname: Koole
authors.forename: Sopheak
authors.initials: S
authors.lastname: Thai
authors.forename: Lut
authors.initials: L
authors.lastname: Lynen
authors.forename: Jan
authors.initials: J
authors.lastname: Jacobs
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D016957:Burkholderia pseudomallei / Q000187:drug effects / Q000302:isolation & purification; D002160:Cambodia / Q000453:epidemiology; D015780:Carbapenems / Q000008:administration & dosage / Q000627:therapeutic use; D002511:Cephalosporins / Q000008:administration & dosage / Q000627:therapeutic use; D003924:Diabetes Mellitus, Type 2 / Q000503:physiopathology; D003951:Diagnostic Errors; D004318:Doxycycline / Q000008:administration & dosage / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008297:Male; D008554:Melioidosis / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology* / Q000401:mortality; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D012307:Risk Factors; D013420:Sulfamethoxazole / Q000008:administration & dosage / Q000627:therapeutic use; D015996:Survival Rate; D014295:Trimethoprim / Q000008:administration & dosage / Q000627:therapeutic use
chemical_list: D015780:Carbapenems; D002511:Cephalosporins; D014295:Trimethoprim; D013420:Sulfamethoxazole; D004318:Doxycycline