title: Hoofbeats and zebras: neurodegenerative disorder presenting as a "first episode" of psychosis.
abstract: Neurodegenerative disorders can include diverse neuropsychiatric symptoms. Here we present a case referred to a "first-episode" psychosis clinic with socio-occupational decline, auditory hallucinations and paranoid ideation who subsequently exhibited a rapid, severe cognitive and behavioral decline. The brain magnetic resonance imaging findings of the patient have shown a progressive cortical atrophy prominent in the frontal lobes due to a neurodegenerative disorder.
authors.affiliation: Department of Psychiatry, Yale University, School of Medicine, New Haven, CT 06519, USA. banu.ozyuksel@yale.edu
authors.forename: Banu
authors.initials: B
authors.lastname: Ozkan
authors.forename: Vivek
authors.initials: V
authors.lastname: Phutane
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Jonas
authors.forename: Cenk
authors.initials: C
authors.lastname: Tek
authors.forename: Vinod
authors.initials: V
authors.lastname: Srihari
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D057180:Frontotemporal Dementia / Q000175:diagnosis* / Q000503:physiopathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D017063:Outcome Assessment, Health Care; D011618:Psychotic Disorders / Q000503:physiopathology*