title: Detection of extended-spectrum-beta-lactamase-positive Escherichia coli in bile isolates from two dogs with bacterial cholangiohepatitis.
abstract: This is the first report of Escherichia coli isolates producing CTX-M-15, the predominant type of extended-spectrum β-lactamase (ESBL) associated with clinical disease in humans in the United Kingdom, in a United Kingdom pet dog. This report also describes the first isolation of CTX-M/Tem ESBL-positive E. coli from bile in dogs with hepatobiliary disease.
authors.affiliation: Diagnostic Microbiology, University of Liverpool, Leahurst Campus, Neston, Cheshire CH64 7TE, UK. d.timofte@liv.ac.uk
authors.forename: Dorina
authors.initials: D
authors.lastname: Timofte
authors.forename: Julien
authors.initials: J
authors.lastname: Dandrieux
authors.forename: Andrew
authors.initials: A
authors.lastname: Wattret
authors.forename: Jenny
authors.initials: J
authors.lastname: Fick
authors.forename: Nicola J
authors.initials: NJ
authors.lastname: Williams
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001646:Bile / Q000382:microbiology; D002761:Cholangitis / Q000150:complications / Q000382:microbiology / Q000662:veterinary*; D004283:Dog Diseases / Q000382:microbiology*; D004285:Dogs; D004926:Escherichia coli / Q000201:enzymology* / Q000302:isolation & purification; D004927:Escherichia coli Infections / Q000150:complications / Q000382:microbiology / Q000662:veterinary*; D005260:Female; D006520:Hepatitis, Animal / Q000150:complications* / Q000382:microbiology; D008826:Microbial Sensitivity Tests; D006113:United Kingdom; D001618:beta-Lactamases / Q000032:analysis*
chemical_list: D000900:Anti-Bacterial Agents; C473109:beta-lactamase CTX-M-15; D001618:beta-Lactamases