title: A triazine bridged p-phenylenevinylene polymer film for biomolecular patterning.
abstract: Photo-reaction by UV irradiation of a highly fluorescent s-triazine bridged p-phenylenevinylene polymer resulted in micro and submicron fluorescent pattern because carbonyl group (C=O) was generated from vinylene group (C=C) through the photo-oxidation. This fluorescent pattern could be used for micro scale cell patterning as well as submicron scale biomolecules patterning such as proteins. When exposed to a solution containing biomolecules, the polymeric patterns were selectively coated with biomoleucles, to result in biomolecular patterns. In particular, the UV exposed area of the poly[4,6-bis(phenoxy)-2-diphenylamino-s-triazine]co(2, 5-bis(trimethylsily)-1,4-phenylenevinylene) (DTSPV) patterns was highly selective toward fluorescein isothiocyanate (FITC) conjugated-collagen. These studies provide an exciting opportunity for tissue engineering and fundamental understanding of the mechanisms of cellular adhesion, proliferation, and differentiation.
authors.affiliation: Department of Chemical and Biomolecular Engineering, Yonsei University, 262 Seongsanno, Seodaemun-gu, Seoul 120-749, Korea.
authors.forename: Jiyea
authors.initials: J
authors.lastname: Lee
authors.forename: Jungmok
authors.initials: J
authors.lastname: You
authors.forename: Eunkyoung
authors.initials: E
authors.lastname: Kim
mesh_terms: D000327:Adsorption; D011108:Polymers / Q000737:chemistry*; D011145:Polyvinyls / Q000737:chemistry*; D013056:Spectrophotometry, Ultraviolet; D014227:Triazines / Q000737:chemistry*; D014297:Trimethylsilyl Compounds / Q000737:chemistry*; D014466:Ultraviolet Rays
chemical_list: D011108:Polymers; D011145:Polyvinyls; D014227:Triazines; D014297:Trimethylsilyl Compounds; C560107:poly(4,6-bis(phenoxy)-2-diphenylamino-s-triazine)co(2,5-bis(trimethylsily)-1,4-phenylenevinylene)