title: Gynecological fertility-sparing surgery.
abstract: The implementation of early detection protocols and advanced treatment strategies has significantly improved survival outcomes for gynecologic cancer patients. The improvement of oncological outcomes has led to an increased attention toward Quality of Life issues, including the childbearing potential for young women. Traditionally the surgical treatment of cervical, endometrial and ovarian cancers involves the removal of the uterus and adnexa, irrespective of the impact on fertility and parenthood and regardless of patient desires. For young women affected by gynecological malignancies at an apparently early stage, fertility-sparing procedures could be offered. The aim of our review is to going through the available evidence in the Literature and to evaluate the current state of art regarding fertility-sparing procedures for women with gynecological malignancies in terms of oncological and fertility outcomes.
authors.affiliation: Department of Gynecology, Cancer Center, IRCCS Humanitas Clinical Institute, Via Manzoni 56, 20089 Rozzano, Milan, Italy. domenico.vitobello@tin.it
authors.forename: D
authors.initials: D
authors.lastname: Vitobello
authors.forename: G
authors.initials: G
authors.lastname: Siesto
authors.forename: C
authors.initials: C
authors.lastname: Bulletti
authors.forename: A
authors.initials: A
authors.lastname: Accardi
authors.forename: P E
authors.initials: PE
authors.lastname: Levi Setti
mesh_terms: D002277:Carcinoma / Q000150:complications / Q000601:surgery*; D005260:Female; D059247:Fertility Preservation / Q000379:methods*; D005833:Genital Neoplasms, Female / Q000150:complications / Q000601:surgery*; D013509:Gynecologic Surgical Procedures / Q000009:adverse effects / Q000379:methods*; D006801:Humans; D007247:Infertility, Female / Q000209:etiology / Q000517:prevention & control; D019060:Minimally Invasive Surgical Procedures / Q000379:methods; D009373:Neoplasms, Germ Cell and Embryonal / Q000150:complications / Q000601:surgery*; D059351:Organ Sparing Treatments / Q000379:methods*; D011247:Pregnancy; D016896:Treatment Outcome