title: Intraocular pressure and ocular perfusion during hemodialysis.
abstract: OBJECTIVE
  To evaluate the intraocular pressure and ocular perfusion pressure during a hemodialysis.
  
  
  METHODS
  Sixty-seven eyes from thirty-five patients were evaluated at the beggining of hemodialysis, 2 hours and 4 hours after initiation. Intraocular pressure was evaluated using a Tonopen. Systolic and diastolic arterial pressures were measured with a manual sphygmomanometer. The ocular perfusion pressure was estimated by measuring the difference between 2/3 of the mean arterial pressure and the intraocular pressure values. Generalized estimating equations were used to evaluate the difference between the repeated measurements using the appropriate correction for inter-eye dependency.
  
  
  RESULTS
  There was no statistically significant difference in ocular perfusion pressure, in intraocular pressure (p=0.93) and in systolic arterial pressure (p=0.92) at the three time points (p=0.69). But, when analyzing the extreme values, some patients exhibited lower diastolic perfusion pressures at all time points.
  
  
  CONCLUSIONS
  Our results did not support the view that significant changes in ocular perfusion pressure and intraocular pressure occur during hemodialysis session. However, we observed that some patients exhibited lower diastolic perfusion pressures, which could be a poor prognostic factor for glaucoma patients.
authors.affiliation: Ophthalmology Department, Universidade Federal de São Paulo, Brazil. carolepm@gmail.com
authors.forename: Carolina Pelegrini
authors.initials: CP
authors.lastname: Barbosa
authors.forename: Francisco Rosa
authors.initials: FR
authors.lastname: Stefanini
authors.forename: Fernando
authors.initials: F
authors.lastname: Penha
authors.forename: Miguel Ângelo
authors.initials: MÂ
authors.lastname: Góes
authors.forename: Sérgio Antonio
authors.initials: SA
authors.lastname: Draibe
authors.forename: Maria Eugênia
authors.initials: ME
authors.lastname: Canziani
authors.forename: Augusto
authors.initials: A
authors.lastname: Paranhos Junior
mesh_terms: D000328:Adult; D000368:Aged; D000704:Analysis of Variance; D001794:Blood Pressure / Q000502:physiology; D005123:Eye / Q000098:blood supply*; D005260:Female; D005901:Glaucoma / Q000503:physiopathology; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis; D012307:Risk Factors; D013997:Time Factors