title: Changes in the thickness and stiffness of plantar soft tissues in people with diabetic peripheral neuropathy.
abstract: OBJECTIVE
  To compare the thickness and stiffness of plantar soft tissues between people with diabetic peripheral neuropathy (DPN) and healthy subjects.
  
  
  METHODS
  Cross-sectional study.
  
  
  METHODS
  University research laboratory.
  
  
  METHODS
  Subjects with DPN (n=70 [35 men, 35 women]; mean age ± SD, 65.4 ± 8.6y) and healthy control subjects (n=54 [12 men, 42 women]; mean age ± SD, 57.9 ± 6.1y) were recruited.
  
  
  METHODS
  Not applicable.
  
  
  METHODS
  The thickness and stiffness of the plantar soft tissues were measured by the tissue ultrasound palpation system over the pulp of the big toe (BT), first metatarsal head (MTH), second MTH, and the heel.
  
  
  RESULTS
  No significant difference in the thickness of the plantar soft tissues was found in any measurement site between the diabetic group and control group. The plantar soft tissues of the DPN group were significantly stiffer than those of the control group at the BT (85.29 kPa vs 50.49 kPa), first MTH (96.29 kPa vs 62.05 kPa), second MTH (84.77 kPa vs 52.93 kPa), and the heel (65.62 kPa vs 44.95 kPa) (all P<.01).
  
  
  CONCLUSIONS
  People with DPN tend to have stiffer plantar tissues than do healthy control subjects. The stiffer plantar soft tissues may reduce the cushioning effects of the foot during walking for people with DPN.
authors.affiliation: Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hong Kong, China.
authors.forename: Jia-Hui
authors.initials: JH
authors.lastname: Sun
authors.forename: Benson K
authors.initials: BK
authors.lastname: Cheng
authors.forename: Yong-Ping
authors.initials: YP
authors.lastname: Zheng
authors.forename: Yan-Ping
authors.initials: YP
authors.lastname: Huang
authors.forename: Jenny Y
authors.initials: JY
authors.lastname: Leung
authors.forename: Gladys L
authors.initials: GL
authors.lastname: Cheing
mesh_terms: D000368:Aged; D003430:Cross-Sectional Studies; D003929:Diabetic Neuropathies / Q000473:pathology*; D005260:Female; D005528:Foot / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged