title: [Predictors of Wingspan in-stent restenosis for the treatment of symptomatic intracranial arterial stenosis].
abstract: OBJECTIVE
  To analyze the predictors of Wingspan in-stent restenosis (ISR) for the treatment of symptomatic intracranial arterial stenosis.
  
  
  METHODS
  Between January 2007 and November 2009, 42 patients with symptomatic intracranial arterial stenosis registered in Nanjing stroke registry program (NSRP) were treated with Wingspan stent system. Clinical and follow-up results were retrospectively analyzed. They were divided into the non-restenosis and restenosis groups according to their follow-up imaging data. ISR was defined as > 50% stenosis within 5 mm or adjacent to stent or an absolute luminal loss > 20%. The analysis of stepwise multivariate Cox regression was performed to evaluate the independent predictive factors.
  
  
  RESULTS
  ISR was found in 15 patients (15/42, 35.7%) with 16 lesions (16/43, 37.2%) at a median follow-up period of 7 months (range: 4 - 23). Diabetes (HR = 0.281; 95%CI = 0.088 - 0.898; P = 0.032) and stent diameter (HR = 0.213; 95%CI = 0.049 - 0.918; P = 0.038) were two independent predictors for ISR.
  
  
  CONCLUSIONS
  Diabetes and stent diameter may be two independent predictors for ISR after a treatment of Wingspan system.
authors.affiliation: Department of Neurology, Jinling Hospital, Nanjing University School of Medicine, China.
authors.forename: Min-min
authors.initials: MM
authors.lastname: Ma
authors.forename: Qin
authors.initials: Q
authors.lastname: Yin
authors.forename: Ge-lin
authors.initials: GL
authors.lastname: Xu
authors.forename: Ren-liang
authors.initials: RL
authors.lastname: Zhang
authors.forename: Shuang-gen
authors.initials: SG
authors.lastname: Zhu
authors.forename: Xin-ying
authors.initials: XY
authors.lastname: Fan
authors.forename: Wu-sheng
authors.initials: WS
authors.lastname: Zhu
authors.forename: Xin-feng
authors.initials: XF
authors.lastname: Liu
mesh_terms: D000328:Adult; D000368:Aged; D000800:Angioplasty, Balloon; D023903:Coronary Restenosis / Q000453:epidemiology* / Q000628:therapy; D003920:Diabetes Mellitus / Q000453:epidemiology; D005260:Female; D006083:Graft Occlusion, Vascular / Q000453:epidemiology* / Q000628:therapy; D006801:Humans; D002537:Intracranial Arteriosclerosis / Q000628:therapy; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D015607:Stents; D016896:Treatment Outcome