title: Inflammation: cell recruitment versus local proliferation.
abstract: Inflammation leads to local accumulation of macrophages. A new study shows that macrophage accumulation in inflammatory reactions dominated by type 2 immune responses is a result of local cell proliferation as opposed to recruitment of monocytes from the blood.
authors.affiliation: Institute for Medical Microbiology, Immunology and Hygiene, Technische Universität München, Munich, Germany. laura.helming@mikrobio.med.tum.de
authors.forename: Laura
authors.initials: L
authors.lastname: Helming
mesh_terms: D000818:Animals; D000971:Antineoplastic Combined Chemotherapy Protocols; D001769:Blood; D049109:Cell Proliferation; D002945:Cisplatin; D005368:Filariasis / Q000276:immunology; D005370:Filarioidea / Q000276:immunology; D007069:Ifosfamide; D007249:Inflammation / Q000276:immunology*; D015847:Interleukin-4 / Q000276:immunology; D008262:Macrophage Activation; D008264:Macrophages / Q000166:cytology / Q000276:immunology*; D016685:Mitomycin; D009000:Monocytes / Q000166:cytology / Q000276:immunology; D018418:Th2 Cells / Q000276:immunology*
chemical_list: D015847:Interleukin-4; D016685:Mitomycin; D002945:Cisplatin; D007069:Ifosfamide