title: Noncoding RNA, antigenic variation, and the virulence genes of Plasmodium falciparum.
abstract: Long non-coding RNAs (lncRNA) are being increasingly recognized as important regulators of gene expression. A recent paper in Genome Biology reports the identification of a lncRNA family in Plasmodium falciparum, the cause of the most deadly form of malaria, that may help to explain the mechanism of antigenic variation in virulence genes of this important pathogen.
authors.affiliation: Biomedical Sciences Program, University of California, San Diego, La Jolla, 92093, USA.
authors.forename: A Taylor
authors.initials: AT
authors.lastname: Bright
authors.forename: Elizabeth A
authors.initials: EA
authors.lastname: Winzeler
mesh_terms: D000818:Animals; D000940:Antigenic Variation / Q000235:genetics*; D006801:Humans; D016778:Malaria, Falciparum / Q000469:parasitology; D010963:Plasmodium falciparum / Q000235:genetics / Q000276:immunology* / Q000472:pathogenicity; D022661:RNA, Untranslated / Q000235:genetics*; D014774:Virulence / Q000235:genetics*
chemical_list: D022661:RNA, Untranslated