title: Y-haplotype screening of local patrilineages followed by autosomal STR typing can detect likely perpetrators in some populations.
abstract: The male-specific, human Y-chromosomal short tandem repeats (Y-STRs) are very useful in forensic analysis and human evolution studies. The authors report two sexual crime cases in which the perpetrators were successfully traced using Y-haplotype screening of local patrilineages followed by autosomal STR typing. First, several main local patrilineages from local cases were investigated using Y-STR haplotyping, aimed to find the pedigrees whose haplotypes were identical or similar to those of the crime scene samples. Then, several key suspects were defined from the screened pedigrees, and autosomal STR typing was performed to identify the perpetrator of the crime. The application of Y-haplotype screening of local patrilineages followed by autosomal STR typing in these two cases demonstrates its usefulness for solving sexually related crimes in certain populations.
authors.affiliation: Faculty of Forensic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China. huangdaixin@mails.tjmu.edu.cn
authors.forename: Daixin
authors.initials: D
authors.lastname: Huang
authors.forename: Shaoxing
authors.initials: S
authors.lastname: Shi
authors.forename: Chuanhong
authors.initials: C
authors.lastname: Zhu
authors.forename: Shaohua
authors.initials: S
authors.lastname: Yi
authors.forename: Wei
authors.initials: W
authors.lastname: Ma
authors.forename: Haisheng
authors.initials: H
authors.lastname: Wang
authors.forename: Huamin
authors.initials: H
authors.lastname: Li
mesh_terms: D000017:ABO Blood-Group System / Q000235:genetics; D000328:Adult; D000369:Aged, 80 and over; D041322:Chromosomes, Human, Y; D016172:DNA Fingerprinting / Q000379:methods*; D005260:Female; D005838:Genotype; D006239:Haplotypes; D006801:Humans; D008297:Male; D018895:Microsatellite Repeats; D016133:Polymerase Chain Reaction; D011902:Rape; D012661:Semen / Q000737:chemistry
chemical_list: D000017:ABO Blood-Group System