title: Intentionally induced swirling flow may improve the hemodynamic performance of coronary bifurcation stenting.
abstract: OBJECTIVE
  Bifurcation stenting represents a challenge for the high rate of restenosis that has close correlations with local hemodynamics. This study sought to test the hypothesis that by intentionally inducing swirling flow the hemodynamic performance of bifurcation stenting can be improved.
  
  
  METHODS
  The hemodynamics of bifurcation stenting with and without swirling flows were numerically simulated and compared.
  
  
  RESULTS
  The results revealed that swirling flow significantly suppressed flow disturbance of blood at the bifurcation and WSS at two critical regions, the outer wall of the bifurcation ostium and the floor wall opposite the branching, was enhanced.
  
  
  CONCLUSIONS
  This study therefore suggests that intentionally inducing swirling flow might be a good strategy in bifurcation stenting.
authors.affiliation: Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, School of Biological Science and Medical Engineering, Beihang University, Beijing 100191, China.
authors.forename: Anqiang
authors.initials: A
authors.lastname: Sun
authors.forename: Yubo
authors.initials: Y
authors.lastname: Fan
authors.forename: Xiaoyan
authors.initials: X
authors.lastname: Deng
mesh_terms: D015906:Angioplasty, Balloon, Coronary / Q000009:adverse effects / Q000295:instrumentation*; D001783:Blood Flow Velocity; D003198:Computer Simulation; D003324:Coronary Artery Disease / Q000503:physiopathology / Q000628:therapy*; D003326:Coronary Circulation; D023903:Coronary Restenosis / Q000209:etiology / Q000503:physiopathology / Q000517:prevention & control; D006439:Hemodynamics; D006801:Humans; D008955:Models, Cardiovascular; D009716:Numerical Analysis, Computer-Assisted; D011474:Prosthesis Design; D012039:Regional Blood Flow; D015607:Stents; D013314:Stress, Mechanical; D016896:Treatment Outcome