title: Ilizarov hip reconstruction for the management of advanced osteonecrosis in an adolescent with leukemia.
abstract: With advances in chemotherapy, long-term survival for childhood leukemia is improving. However, chemotherapy-induced osteonecrosis of the proximal femur remains a challenging problem. We present a case of an adolescent female with advanced osteonecrosis of the proximal femur after chemotherapy for acute lymphoblastic leukemia. She underwent an Ilizarov hip reconstruction with a subtrochanteric valgus extension osteotomy and distal femoral lengthening with varus angulation using an external fixator. At a 3-year follow-up, her symptoms and gait had markedly improved. On the basis of this preliminary report, Ilizarov hip reconstruction is a viable alternative for advanced osteonecrosis of the proximal femur in an adolescent.
authors.affiliation: Department of Orthopedics, University of Medicine and Dentistry of New Jersey, New Jersey Medical School, 90 Bergen Street, Newark, NJ 07103, USA. sabharsa@umdnj.edu
authors.forename: Sanjeev
authors.initials: S
authors.lastname: Sabharwal
authors.forename: Robert
authors.initials: R
authors.lastname: MacLeod
mesh_terms: D000293:Adolescent; D000970:Antineoplastic Agents / Q000009:adverse effects / Q000627:therapeutic use; D020821:Dystonic Disorders / Q000139:chemically induced / Q000601:surgery; D005260:Female; D005269:Femur / Q000601:surgery; D005271:Femur Head Necrosis / Q000139:chemically induced / Q000601:surgery*; D005684:Gait; D006801:Humans; D018889:Ilizarov Technique; D016916:Joint Deformities, Acquired / Q000139:chemically induced / Q000601:surgery*; D010027:Osteotomy / Q000379:methods; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications / Q000188:drug therapy / Q000601:surgery*; D019651:Plastic Surgery Procedures; D020127:Recovery of Function
chemical_list: D000970:Antineoplastic Agents