title: Wide optic nerve canal decompression for the treatment of blindness resulting from an indirect optic nerve injury.
abstract: OBJECTIVE
  The objective of this study was to investigate the efficacy of wide decompression of the optic canal for treating blindness resulting from an indirect optic nerve injury.
  
  
  METHODS
  Forty-three patients with blindness resulting from an indirect optic nerve injury were retrospectively reviewed for preoperative vision, preoperative image, operative video, postoperative visual acuity, complications, and follow-up results.
  
  
  RESULTS
  The 43 patients included 37 men and 6 women with an age range from 15 to 41 years (average, 31.8 years). On preoperative examination, all patients presented blindness in the involved eye. Six patients had an optic canal fracture. During the operation, a compression of the optic canal from a bony fragment was found in 1 patient, and an optic nerve sheath hematoma was found in another patient. After the operation, 6 patients developed cerebrospinal fluid rhinorrhea but recovered with conservative therapy. At the 6-month follow-up, visual acuity was improved to 3/60 in 3 patients, 5 patients could count fingers, 3 patients could see hand motions, and 3 patients retained light perception in the afflicted eye. The vision in other patients remained nonperceptive to light.
  
  
  CONCLUSIONS
  Although the prognosis for blindness resulting from an indirect optic injury is poor, some patients have a chance to recover with enough decompression on the traumatized optic nerve. Poor results of this procedure may be related to the severity of the primary optic nerve injury.
authors.affiliation: Neurosurgical Department, Ninth People's Hospital of Shanghai Affiliated with Shanghai Jiaotong University, Shanghai, People's Republic of China. gzlysr@126.com
authors.forename: Guo
authors.initials: G
authors.lastname: Zhilin
authors.forename: Ouyang
authors.initials: O
authors.lastname: Huoniu
authors.forename: Cheng
authors.initials: C
authors.lastname: Zhihua
authors.forename: Ding
authors.initials: D
authors.lastname: Guorong
mesh_terms: D000293:Adolescent; D000328:Adult; D001766:Blindness / Q000209:etiology / Q000601:surgery*; D002559:Cerebrospinal Fluid Rhinorrhea / Q000209:etiology; D019299:Decompression, Surgical / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006406:Hematoma / Q000150:complications / Q000601:surgery; D006801:Humans; D008297:Male; D009408:Nerve Compression Syndromes / Q000209:etiology / Q000601:surgery; D020221:Optic Nerve Injuries / Q000150:complications*; D011183:Postoperative Complications; D020127:Recovery of Function / Q000502:physiology; D012189:Retrospective Studies; D012887:Skull Fractures / Q000150:complications / Q000601:surgery; D013100:Sphenoid Bone / Q000293:injuries / Q000601:surgery*; D016896:Treatment Outcome; D014792:Visual Acuity / Q000502:physiology; D055815:Young Adult