title: Importance of proper scaling of aerobic power when relating to cardiometabolic risk factors in children.
abstract: BACKGROUND
  The relationship between cardiometabolic risk factors (CMRF) and aerobic power (VO(2max)) scaled as mL O(2) per kilogram body mass is controversial because mass includes both fat and fat-free mass, and fat mass is independently associated with the CMRF.
  
  
  OBJECTIVE
  To examine common units used to scale VO(2max) and their relationships to mean blood pressure (MBP), total cholesterol (TC), HDL cholesterol, triglycerides (TG), insulin resistance (HOMA-IR) and cumulative risk score (z-score).
  
  
  METHODS
  1784, 8-18 year-old youths, 938 girls and 886 boys.
  
  
  METHODS
  Fasting blood samples were obtained. VO(2max) was estimated in mL/min from cycle ergometry and scaled to body mass (kg), fat free mass (kg(FFM)), body surface area (m(2)), height (cm) and allometric (mL/kg(0.67)/min).
  
  
  RESULTS
  Unadjusted correlations between CMRF and many of the scaled VO(2max) units were significant (p < 0.0001), especially for MBP, HOMA-IR, HDL and z-score, with lower correlations for TC and TG. After adjusting for ancestry, sex, height and body fat associations were greatly weakened (r < 0.09), except for MBP.
  
  
  CONCLUSIONS
  On a population basis, the physical characteristics of the child, especially body fat, are more related to CMRF than any scaled units of VO(2max); thus care is needed when relating fitness and health issues.
authors.affiliation: Department of Exercise and Sport Science, University of North Carolina, Chapel Hill, NC, USA. exphys@email.unc.edu
authors.forename: Robert G
authors.initials: RG
authors.lastname: McMurray
authors.forename: Peter A
authors.initials: PA
authors.lastname: Hosick
authors.forename: Anna
authors.initials: A
authors.lastname: Bugge
mesh_terms: D000293:Adolescent; D000332:Aerobiosis; D000886:Anthropometry; D001794:Blood Pressure / Q000502:physiology; D002318:Cardiovascular Diseases / Q000453:epidemiology* / Q000378:metabolism* / Q000503:physiopathology; D002648:Child; D005260:Female; D006801:Humans; D007333:Insulin Resistance / Q000502:physiology; D008297:Male; D024821:Metabolic Syndrome / Q000453:epidemiology* / Q000378:metabolism* / Q000503:physiopathology; D009657:North Carolina / Q000453:epidemiology; D010101:Oxygen Consumption / Q000502:physiology; D012307:Risk Factors