title: The low frequency of reported sexual dysfunction in Asian patients with schizophrenia (2001-2009): low occurrence or ignored side effect?
abstract: OBJECTIVE
  The purpose of the study was to evaluate the frequency of reported sexual dysfunction (SD) in schizophrenia and its associations with sociodemographic and clinical variables in selected Asian countries.
  
  
  METHODS
  A total of 5877 schizophrenia patients in nine Asian countries and territories were examined between 2001 and 2009. The patients' sociodemographic and clinical characteristics, prescription of psychotropic drugs, and drug-induced side effects were recorded using a standardized protocol and data collection. SD was evaluated as "present" or "absent" according to the clinical judgment of experienced psychiatrists.
  
  
  RESULTS
  The frequency of reported SD in the whole sample in women and men was 3.0%, 0.8%, and 4.6%, respectively, with variations across study sites. In the multivariate analyses, male sex, more second-generation antipsychotics, benzodiazepines, and antidepressants were independently associated with higher likelihood of reported SD, whereas negative symptoms had an inverse association with reported SD.
  
  
  CONCLUSIONS
  The results of this study indicate that SD was seldom recorded as a side effect by Asian psychiatrists while treating patients with schizophrenia. It is unclear whether the low prevalence of reported SD compared with Western data is real or whether the results are being insufficiently recognized.
authors.affiliation: Department of Psychiatry, Chinese University of Hong Kong, Hong Kong, China. xyutly@gmail.com
authors.forename: Yu-Tao
authors.initials: YT
authors.lastname: Xiang
authors.forename: Chuan-Yue
authors.initials: CY
authors.lastname: Wang
authors.forename: Tian-Mei
authors.initials: TM
authors.lastname: Si
authors.forename: Edwin H M
authors.initials: EH
authors.lastname: Lee
authors.forename: Yan-Ling
authors.initials: YL
authors.lastname: He
authors.forename: Gabor S
authors.initials: GS
authors.lastname: Ungvari
authors.forename: Helen F K
authors.initials: HF
authors.lastname: Chiu
authors.forename: Shu-Yu
authors.initials: SY
authors.lastname: Yang
authors.forename: Mian-Yoon
authors.initials: MY
authors.lastname: Chong
authors.forename: Chay-Hoon
authors.initials: CH
authors.lastname: Tan
authors.forename: Ee-Heok
authors.initials: EH
authors.lastname: Kua
authors.forename: Senta
authors.initials: S
authors.lastname: Fujii
authors.forename: Kang
authors.initials: K
authors.lastname: Sim
authors.forename: Michael K H
authors.initials: MK
authors.lastname: Yong
authors.forename: Jitendra K
authors.initials: JK
authors.lastname: Trivedi
authors.forename: Eun-Kee
authors.initials: EK
authors.lastname: Chung
authors.forename: Pichet
authors.initials: P
authors.lastname: Udomratn
authors.forename: Kok-Yoon
authors.initials: KY
authors.lastname: Chee
authors.forename: Norman
authors.initials: N
authors.lastname: Sartorius
authors.forename: Naotaka
authors.initials: N
authors.lastname: Shinfuku
mesh_terms: D000328:Adult; D000928:Antidepressive Agents / Q000009:adverse effects / Q000627:therapeutic use; D014150:Antipsychotic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D001208:Asia; D001569:Benzodiazepines / Q000009:adverse effects / Q000627:therapeutic use; D003430:Cross-Sectional Studies; D039721:Diagnostic and Statistical Manual of Mental Disorders; D005260:Female; D006306:Health Surveys; D006801:Humans; D038801:International Classification of Diseases; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D015995:Prevalence; D012559:Schizophrenia / Q000150:complications* / Q000188:drug therapy; D012727:Sex Characteristics; D012735:Sexual Dysfunction, Physiological / Q000139:chemically induced / Q000150:complications / Q000453:epidemiology*; D020018:Sexual Dysfunctions, Psychological / Q000139:chemically induced / Q000150:complications / Q000453:epidemiology*
chemical_list: D000928:Antidepressive Agents; D014150:Antipsychotic Agents; D001569:Benzodiazepines