title: Adrenalectomy in dogs with adrenal gland tumors: 52 cases (2002-2008).
abstract: OBJECTIVE
  To evaluate predictors of survival time in dogs undergoing adrenalectomy and identify risk factors associated with adrenal gland tumor metastasis and vein thrombosis.
  
  
  METHODS
  Retrospective case series.
  
  
  METHODS
  52 dogs with primary adrenal gland tumors.
  
  
  METHODS
  Medical records were reviewed. Signalment, tumor features, and information from surgical procedures were evaluated to identify factors predictive of overall survival time, which was defined as the time from surgery until death. The association between metastasis or vein thrombosis and tumor type, size, and site (right or left adrenal gland) was investigated.
  
  
  RESULTS
  On the basis of results of univariate analysis, survival time was significantly shorter for dogs with adenocarcinoma, tumor major axis length ≥ 5 cm, metastasis, and vein thrombosis and when adrenalectomy was combined with an additional abdominal surgical intervention. On multivariate analysis, survival time was significantly shorter for dogs with an adrenal gland tumor with major axis length ≥ 5 cm and for dogs with metastasis or vein thrombosis. Significant associations were found between metastasis and adenocarcinoma and between vein thrombosis and tumors with major axis length ≥ 5 cm.
  
  
  CONCLUSIONS
  Dogs with an adrenal gland tumor with major axis length ≥ 5 cm, documented metastasis, or vein thrombosis had a poorer prognosis. Metastasis was more frequent in dogs with adenocarcinoma and vein thrombosis when tumors were ≥ 5 cm in length.
authors.affiliation: Clinica Veterinaria Nerviano, Via Lampugnani 3, Nerviano, 20014 Milan, Italy. fidomas@hotmail.com
authors.forename: Federico
authors.initials: F
authors.lastname: Massari
authors.forename: Stefano
authors.initials: S
authors.lastname: Nicoli
authors.forename: Giorgio
authors.initials: G
authors.lastname: Romanelli
authors.forename: Paolo
authors.initials: P
authors.lastname: Buracco
authors.forename: Eric
authors.initials: E
authors.lastname: Zini
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology / Q000601:surgery / Q000662:veterinary; D000236:Adenoma / Q000473:pathology / Q000601:surgery / Q000662:veterinary; D000310:Adrenal Gland Neoplasms / Q000473:pathology / Q000601:surgery / Q000662:veterinary*; D000315:Adrenalectomy / Q000662:veterinary*; D000818:Animals; D004283:Dog Diseases / Q000601:surgery*; D004285:Dogs; D005260:Female; D008297:Male; D018209:Myelolipoma / Q000473:pathology / Q000601:surgery / Q000662:veterinary; D009362:Neoplasm Metastasis; D010673:Pheochromocytoma / Q000473:pathology / Q000601:surgery / Q000662:veterinary; D012189:Retrospective Studies