title: Antioxidant, electrochemical, thermal, antimicrobial and alkane oxidation properties of tridentate Schiff base ligands and their metal complexes.
abstract: In this study, two Schiff base ligands (HL(1) and HL(2)) and their Cu(II), Co(II), Ni(II), Pd(II) and Ru(III) metal complexes were synthesized and characterized by the analytical and spectroscopic methods. Alkane oxidation activities of the metal complexes were studied on cyclohexane as substrate. The ligands and their metal complexes were evaluated for their antimicrobial activity against Corynebacterium xerosis, Bacillus brevis, Bacillus megaterium, Bacillus cereus, Mycobacterium smegmatis, Staphylococcus aureus, Micrococcus luteus and Enterococcus faecalis (as gram-positive bacteria) and Pseudomonas aeruginosa, Klebsiella pneumoniae, Escherichia coli, Yersinia enterocolitica, Klebsiella fragilis, Saccharomyces cerevisiae, and Candida albicans (as gram-negative bacteria). The antioxidant properties of the Schiff base ligands were evaluated in a series of in vitro tests: 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging and reducing power activity of superoxide anion radical generated non-enzymatic systems. Electrochemical and thermal properties of the compounds were investigated.
authors.affiliation: Kahramanmaraş Sütçü Imam University, Chemistry Department, 46100 K.Maras, Turkey.
authors.forename: Gökhan
authors.initials: G
authors.lastname: Ceyhan
authors.forename: Cumali
authors.initials: C
authors.lastname: Çelik
authors.forename: Serhan
authors.initials: S
authors.lastname: Uruş
authors.forename: İbrahim
authors.initials: İ
authors.lastname: Demirtaş
authors.forename: Mahfuz
authors.initials: M
authors.lastname: Elmastaş
authors.forename: Mehmet
authors.initials: M
authors.lastname: Tümer
mesh_terms: D000473:Alkanes / Q000378:metabolism*; D000890:Anti-Infective Agents / Q000032:analysis / Q000737:chemistry / Q000494:pharmacology; D000975:Antioxidants / Q000032:analysis / Q000737:chemistry / Q000494:pharmacology*; D056831:Coordination Complexes / Q000032:analysis / Q000737:chemistry / Q000494:pharmacology*; D004055:Differential Thermal Analysis; D004563:Electrochemistry; D006090:Gram-Negative Bacteria / Q000187:drug effects / Q000254:growth & development; D006094:Gram-Positive Bacteria / Q000187:drug effects / Q000254:growth & development; D006801:Humans; D008024:Ligands; D008826:Microbial Sensitivity Tests; D008954:Models, Biological; D015394:Molecular Structure; D010084:Oxidation-Reduction / Q000187:drug effects; D012545:Schiff Bases / Q000032:analysis / Q000737:chemistry / Q000494:pharmacology*; D013329:Structure-Activity Relationship
chemical_list: D000473:Alkanes; D000890:Anti-Infective Agents; D000975:Antioxidants; D056831:Coordination Complexes; D008024:Ligands; D012545:Schiff Bases