title: Congenital abnormalities at a tertiary center in Jamaica: an 18-month maternal-fetal medicine experience.
abstract: OBJECTIVE
  The objective of this study was to compare outcomes of patients with prenatally versus postnatally diagnosed congenital abnormalities seen during the first 18 months of a recently established MFM unit.
  
  
  METHODS
  Hospital charts of all congenital abnormalities diagnosed between July 2008 and December 2009 were reviewed. Data collected included: maternal demographics, perinatal outcome, neonatal mortality and morbidity as defined in the Radius trial.
  
  
  RESULTS
  Fifty-five pregnancies with 57 anomalous fetuses were identified: 13 (23%) postnatally and 44 (77%) prenatally. Most frequent postnatally diagnosed anomalies were gastrointestinal (33%), central nervous system (CNS) (16%) and cardiac (16%); whereas prenatally diagnosed were CNS (29%) and genitourinary (23%). Mothers postnatally diagnosed had a 12 kg (17%) greater mean weight; 12 (92%) had anomaly scans reported as normal; birth weight and moderate neonatal morbidity were statistically greater (2.8 vs. 2.13 kg, p < 0.02) and (9/12 vs. 11/29, p < 0.03), respectively. Neonatal morbidity was 6.2 times more likely in the postnatally diagnosed group adjusting for birth weight, gestational age and route of delivery [OR (95% CI) 6.2, (1.2-32.4), p = 0.03].
  
  
  CONCLUSIONS
  Most abnormalities were diagnosed prenatally; however, the majority of postnatally diagnosed had false negative anomaly scans and experienced significantly more moderate neonatal morbidity.
authors.affiliation: Maternal-Fetal Medicine Unit, Department of Obstetrics and Gynaecology, University of the West Indies, Mona, Kingston, Jamaica. nadinej@cwjamaica.com
authors.forename: N
authors.initials: N
authors.lastname: Johnson
authors.forename: K
authors.initials: K
authors.lastname: Bishop
authors.forename: H
authors.initials: H
authors.lastname: Trotman
authors.forename: M
authors.initials: M
authors.lastname: Reid
mesh_terms: D000328:Adult; D000013:Congenital Abnormalities / Q000175:diagnosis / Q000453:epidemiology*; D005260:Female; D005865:Gestational Age; D006801:Humans; D007563:Jamaica / Q000453:epidemiology; D008430:Maternal-Child Health Centers / Q000706:statistics & numerical data; D033261:Maternal-Fetal Relations; D011247:Pregnancy; D011256:Pregnancy Outcome / Q000453:epidemiology*; D011262:Pregnancy Trimester, Second; D011263:Pregnancy Trimester, Third; D011296:Prenatal Diagnosis / Q000706:statistics & numerical data; D012189:Retrospective Studies; D013997:Time Factors; D055815:Young Adult