title: Ethnic variation in estradiol metabolism in reproductive age Asian and white women treated with transdermal estradiol.
abstract: Asian women have significantly higher serum E(2) levels during treatment with transdermal E(2) compared with white women. This finding suggests altered metabolic clearance of this steroid hormone.
authors.affiliation: Department of Obstetrics, Gynecology and Reproductive Sciences, University of California at San Francisco, San Francisco, California 94115-0916, USA. Huddlestonh@obgyn.ucsf.edu
authors.forename: Heather G
authors.initials: HG
authors.lastname: Huddleston
authors.forename: Mitchell P
authors.initials: MP
authors.lastname: Rosen
authors.forename: Mark
authors.initials: M
authors.lastname: Gibson
authors.forename: Marcelle I
authors.initials: MI
authors.lastname: Cedars
authors.forename: Victor Y
authors.initials: VY
authors.lastname: Fujimoto
mesh_terms: D000279:Administration, Cutaneous; D000328:Adult; D000367:Age Factors; D001213:Asian / Q000706:statistics & numerical data*; D015331:Cohort Studies; D004958:Estradiol / Q000097:blood / Q000493:pharmacokinetics* / Q000627:therapeutic use; D004967:Estrogens / Q000097:blood / Q000493:pharmacokinetics / Q000627:therapeutic use; D005260:Female; D020249:Hormone Replacement Therapy; D006801:Humans; D007247:Infertility, Female / Q000188:drug therapy / Q000208:ethnology / Q000378:metabolism; D015999:Multivariate Analysis; D012044:Regression Analysis; D012189:Retrospective Studies; D044465:White People / Q000706:statistics & numerical data*
chemical_list: D004967:Estrogens; D004958:Estradiol