title: Musculoskeletal magnetic resonance imaging suggesting the possibility of liposarcoma: correlation between radiologists' certainty of diagnosis and pathology results.
abstract: OBJECTIVE
  Reliable diagnosis of liposarcoma by magnetic resonance imaging (MRI) is essential for surgical planning. The purpose of this study was to correlate radiologists' certainty of the diagnosis of liposarcoma on musculoskeletal MRI with pathology results.
  
  
  METHODS
  Between January 2001 and February 2009, 105 patients who radiologically suggested liposarcoma on their MRI reports were retrospectively reviewed. Among them, pathologically confirmed 64 patients (benign, 42; malignant, 22) were included. Two musculoskeletal radiologists reviewed MR reports and classified these into 3 groups according to the degree of certainty of liposarcoma (CL) by consensus: C1, high; C2, undetermined; and C3, low. Classified data were compared with pathology results.
  
  
  RESULTS
  The number of cases in each group was C1, 32; C2, 12; and C3, 20. Group C1 included 17 liposarcomas (53%), 7 lipomas, 4 other sarcomas, 2 hibernomas, 1 abscess, and 1 epidermal cyst. There were 11 lipomas (92%) and one liposarcoma in C2. In C3, all patients had lipomas. Fifteen (47%) of 32 variable benign or malignant tumors were incorrectly diagnosed as liposarcomas.
  
  
  CONCLUSIONS
  On the diagnosis of liposarcoma, the radiologists' high degree of CL showed high agreement. However, nonadipose tumors were sometimes misdiagnosed as liposarcomas with a high CL. Therefore, we should consider other soft tissue tumors and benign lipomas for the differential diagnosis of liposarcoma.
authors.affiliation: Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
authors.forename: Yoon Mi
authors.initials: YM
authors.lastname: Lee
authors.forename: Hye Won
authors.initials: HW
authors.lastname: Chung
authors.forename: Myung Jin
authors.initials: MJ
authors.lastname: Shin
authors.forename: Sang Hoon
authors.initials: SH
authors.lastname: Lee
authors.forename: Sam Soo
authors.initials: SS
authors.lastname: Kim
authors.forename: Jong Seok
authors.initials: JS
authors.lastname: Lee
authors.forename: Mi-Jung
authors.initials: MJ
authors.lastname: Kim
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001706:Biopsy; D002648:Child; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008080:Liposarcoma / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012983:Soft Tissue Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery