title: GeT peptides: a single-domain approach to gene delivery.
abstract: A generic peptide sequence for gene delivery is described. The sequence penetrates eukaryotic cells and promotes active DNA transport into mammalian cells (EGFP positive) by undergoing differential membrane-induced folding, which renders it both endosomolytic and antibacterial.
authors.affiliation: National Physical Laboratory, Teddington, TW11 0LW, UK.
authors.forename: Baptiste
authors.initials: B
authors.lastname: Lamarre
authors.forename: Jascindra
authors.initials: J
authors.lastname: Ravi
authors.forename: Maxim G
authors.initials: MG
authors.lastname: Ryadnov
mesh_terms: D000595:Amino Acid Sequence; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000378:metabolism; D002463:Cell Membrane Permeability; D002478:Cells, Cultured; D004247:DNA / Q000008:administration & dosage* / Q000235:genetics; D005347:Fibroblasts / Q000166:cytology / Q000378:metabolism; D018014:Gene Transfer Techniques; D049452:Green Fluorescent Proteins / Q000235:genetics; D006801:Humans; D008969:Molecular Sequence Data; D010455:Peptides / Q000737:chemistry* / Q000378:metabolism*
chemical_list: D000900:Anti-Bacterial Agents; D010455:Peptides; C485184:enhanced green fluorescent protein; D049452:Green Fluorescent Proteins; D004247:DNA