title: Assembly of the isoindolinone core of muironolide A by asymmetric intramolecular Diels-Alder cycloaddition.
abstract: The hexahydro-1H-isoindolin-1-one core of muironolide A was prepared by asymmetric intramolecular Diels-Alder cycloaddition using a variant of the MacMillan organocatalyst which sets the C4,C5 and C11 stereocenters.
authors.affiliation: Department of Chemistry and Biochemistry, University of California San Diego, 9500 Gilman Drive MC0358, La Jolla, California 92093, USA.
authors.forename: Beatris
authors.initials: B
authors.lastname: Flores
authors.forename: Tadeusz F
authors.initials: TF
authors.lastname: Molinski
mesh_terms: D002384:Catalysis; D003500:Cyclization; D007211:Indoles / Q000737:chemistry*; D054833:Isoindoles / Q000737:chemistry*; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D007211:Indoles; D054833:Isoindoles; C568569:muironolide A