title: A fatal case of mesenchymal chondrosarcoma of the mandible.
abstract: A 34-year-old man presented with an expansile, erosive tumor involving the left side of the mandible, with secondary invasion into the maxilla, measuring 13 Χ 7 cm. Microscopic analysis revealed a malignant small round cell neoplasm with focal cartilaginous differentiation. Immunohistochemical analysis revealed positivity for vimentin, NSE and CD99 with primitive small round cells, and S100 positivity with neoplastic chondrocytes. To the best of our knowledge, this is perhaps the largest reported case of mesenchymal chondrosarcoma of the maxillofacial region. Diagnosed as inoperable, he was treated with radiation and chemotherapy only to die within a few months.
authors.affiliation: Department of Surgical Oncology, Cancer Institute WIA, 36 Sardar Patel Road, Adyar, Chennai 600 020, India. dravindkrishnamurthy@yahoo.com
authors.forename: Arvind
authors.initials: A
authors.lastname: Krishnamurthy
authors.forename: Anitha
authors.initials: A
authors.lastname: Vaidhyanathan
authors.forename: Satish
authors.initials: S
authors.lastname: Srinivas
authors.forename: Urmila
authors.initials: U
authors.lastname: Majhi
mesh_terms: D000328:Adult; D018211:Chondrosarcoma, Mesenchymal / Q000175:diagnosis* / Q000188:drug therapy / Q000532:radiotherapy; D003131:Combined Modality Therapy; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D008339:Mandibular Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000532:radiotherapy; D008437:Maxilla / Q000473:pathology; D009361:Neoplasm Invasiveness; D010166:Palliative Care; D011859:Radiography; D013125:Spinal Neoplasms / Q000000981:diagnostic imaging; D013904:Thoracic Vertebrae / Q000000981:diagnostic imaging