title: Frozen section diagnoses of 578 ovarian tumors made by pathologists with and without expertise on gynecologic pathology.
abstract: OBJECTIVE
  Frozen section is an important diagnostic tool to determine the nature of the ovarian masses intraoperatively. The optimal surgical treatment can be achieved by classifying the masses as benign, borderline and malignant. The aim of this retrospective study was to evaluate the accuracy of frozen section diagnosis of ovarian neoplasms and to determine the effects of Gynecologic (Gyn) pathologist or non-Gyn pathologist on frozen section diagnosis.
  
  
  METHODS
  Intraoperative frozen section diagnosis was retrospectively evaluated in 578 patients operated with the suspicion of ovarian neoplasms. We compared the results of frozen section diagnosis by Gyn pathologists (Group 1) and by non-Gyn (Group 2) pathologists.
  
  
  RESULTS
  In 23 patients (3.9%), the tissues were other than ovary. No opinion could be obtained on frozen sections of 14 cases (2.4%). The sensitivities for benign, borderline and malignant tumors for frozen section diagnoses of Gyn pathologists were 99.7%, 89.5%, and 96.3% respectively. The corresponding specificities were 97.6%, 85% and 99%, respectively. Group 2 pathologists had sensitivities and specificities of 97%, 50%, 84.6% and 95.2%, 96.2% and 94.5% for benign, borderline and malignant tumors, respectively. The overall accuracy rate of frozen section was 97.1%.
  
  
  CONCLUSIONS
  Intraoperative frozen section diagnosis has a high accuracy rate for ovarian pathologies. Those rates do increase even more if it is evaluated by the Gyn pathologists.
authors.affiliation: Department of Obstetrics and Gynecology, Dokuz Eylul University School of Medicine, Izmir, Turkey. ozgurbigef@yahoo.com
authors.forename: Ozgur
authors.initials: O
authors.lastname: Bige
authors.forename: Ahmet
authors.initials: A
authors.lastname: Demir
authors.forename: Ugur
authors.initials: U
authors.lastname: Saygili
authors.forename: Funda
authors.initials: F
authors.lastname: Gode
authors.forename: Turhan
authors.initials: T
authors.lastname: Uslu
authors.forename: Meral
authors.initials: M
authors.lastname: Koyuncuoglu
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002983:Clinical Competence; D005260:Female; D005629:Frozen Sections / Q000379:methods / Q000592:standards; D006176:Gynecology / Q000379:methods / Q000592:standards*; D006801:Humans; D007430:Intraoperative Care; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D016612:Paraffin Embedding; D010340:Pathology, Surgical / Q000379:methods / Q000592:standards*; D012189:Retrospective Studies; D055815:Young Adult