title: [Determination of evodiamine and rutacarpine in zhuyu hewei zhitong capsules by HPLC].
abstract: OBJECTIVE
  To develop a HPLC method for the determination of evodiamine and rutacarpine in Zhuyu Hewei Zhitong capsules.
  
  
  METHODS
  The separation was performed at 30 degrees C on an Eclipse XDB-C18 column (4.6 mm x 150 mm, 5 microm) eluted with the mobile phase consisted of acetonitrile-water(45:55). The detection wavelength was 250 nm.
  
  
  RESULTS
  The standard curve for evodiamine is linear in the range of 0.0510-0.560 microg, the average recovery was 97.5% (RSD 1.0%). The standard curve for rutacarpine is linear in the range of 0.0508-0.559 microg, the average recovery was 98.7% (RSD 1.5%).
  
  
  CONCLUSIONS
  The method is specific, accurate and stable. It can be used for detemination of evodiamine and rutacarpine in Zhuyu Hewei Zhitong capsules.
authors.affiliation: Guiyang College of Traditional Chinese Medicine, Guiyang 550002, China. mxp001130@sina.com.cn
authors.forename: Xiuping
authors.initials: X
authors.lastname: Ma
authors.forename: Jiang
authors.initials: J
authors.lastname: Li
authors.forename: Yingbo
authors.initials: Y
authors.lastname: Liu
mesh_terms: D000470:Alkaloids / Q000032:analysis*; D002214:Capsules; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D004365:Drugs, Chinese Herbal / Q000737:chemistry* / Q000592:standards; D016014:Linear Models; D011786:Quality Control; D011799:Quinazolines / Q000032:analysis*; D015203:Reproducibility of Results
chemical_list: D000470:Alkaloids; D002214:Capsules; D004365:Drugs, Chinese Herbal; D011799:Quinazolines; C560377:rutacarpine; C049639:evodiamine