title: [The analysis of AllergyScreen results among allergic patients of different age groups].
abstract: OBJECTIVE
  To investigate the positive rates of some allergens in different age groups of allergic rhinitis patients, and to analyze the relationship between serum specific immunoglobulin E(sIgE) and total immunoglobulin E(IgE).
  
  
  METHODS
  Six hundred and fifty-three patients with allergic rhinitis, tested by AllergyScreen system, were enrolled in our research.
  
  
  RESULTS
  The positive rate of sIgE in all patients was 85.5%. The positive rate of dust mite was the highest with the result of 76.3%, and the positive rate of feline or dogs hair was the lowest of 20.3%. The statistical significance of different positive rate of some allergens were found in the different age groups. All the patients were divided into two groups, one was younger than 18 years old group, which including 18 years old and another was older than 18 years old group. Except Mx, the positive rate of other allergens existed statistical difference. The level of serum total IgE could not reflect the positive rate of sIgE completely.
  
  
  CONCLUSIONS
  It is an effective and reliable method of the diagnosis of allergic rhinitis to combine the analysis of total serum IgE and sIgE levels with patients clinical manifestations. Different strategies should be employed for the prevention and treatment of allergic rhinitis according to their ages.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Renmin Hospital of Wuhan University, Wuhan, 430060,China.
authors.forename: Zhe
authors.initials: Z
authors.lastname: Chen
authors.forename: Zezhang
authors.initials: Z
authors.lastname: Tao
authors.forename: Yuqin
authors.initials: Y
authors.lastname: Deng
authors.forename: Yu
authors.initials: Y
authors.lastname: Xu
authors.forename: Yonggang
authors.initials: Y
authors.lastname: Kong
authors.forename: Bokui
authors.initials: B
authors.lastname: Xiao
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000485:Allergens / Q000032:analysis*; D002648:Child; D005260:Female; D006801:Humans; D007073:Immunoglobulin E / Q000097:blood*; D008297:Male; D008875:Middle Aged; D012221:Rhinitis, Allergic, Perennial / Q000097:blood / Q000175:diagnosis* / Q000276:immunology; D012882:Skin Tests; D055815:Young Adult
chemical_list: D000485:Allergens; D007073:Immunoglobulin E