title: Non-surgical treatment of peri-implantitis using an air-abrasive device or mechanical debridement and local application of chlorhexidine: a prospective, randomized, controlled clinical study.
abstract: OBJECTIVE
  The aim of this prospective, parallel group designed, randomized controlled clinical study was to evaluate the effectiveness of an air-abrasive device (AAD) for non-surgical treatment of peri-implantitis.
  
  
  METHODS
  Thirty patients, each of whom displayed at least one implant with initial to moderate peri-implantitis, were enrolled in an oral hygiene program (OHI) and randomly instrumented using either (1) AAD (amino acid glycine powder) or (2) mechanical debridement using carbon curets and antiseptic therapy with chlorhexidine digluconate (MDA). Clinical parameters were measured at baseline, 3 and 6 months after treatment [e.g. bleeding on probing (BOP), probing depth (PD), clinical attachment level (CAL)].
  
  
  RESULTS
  At 6 months, AAD group revealed significantly higher (p<0.05; unpaired t-test) changes in mean BOP scores when compared with MDA-treated sites (43.5 ± 27.7%versus 11.0 ± 15.7%). Both groups exhibited comparable PD reductions (AAD: 0.6 ± 0.6 mm versus MDA: 0.5 ± 0.6 mm) and CAL gains (AAD: 0.4 ± 0.7 mm versus MDA: 0.5 ± 0.8 mm) (p>0.05; unpaired t-test, respectively).
  
  
  CONCLUSIONS
  Within its limitations, the present study has indicated that (i) both treatment procedures resulted in comparable but limited CAL gains at 6 months, and (ii) OHI+AAD was associated with significantly higher BOP reductions than OHI+MDA.
authors.affiliation: Department of Oral Surgery, Heinrich Heine University, Düsseldorf, Germany.
authors.forename: Narja
authors.initials: N
authors.lastname: Sahm
authors.forename: Jürgen
authors.initials: J
authors.lastname: Becker
authors.forename: Thore
authors.initials: T
authors.lastname: Santel
authors.forename: Frank
authors.initials: F
authors.lastname: Schwarz
mesh_terms: D000287:Administration, Topical; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D020906:Air Abrasion, Dental / Q000295:instrumentation*; D000891:Anti-Infective Agents, Local / Q000008:administration & dosage*; D002710:Chlorhexidine / Q000008:administration & dosage*; D015921:Dental Implants / Q000382:microbiology; D005260:Female; D005998:Glycine; D006801:Humans; D008297:Male; D008875:Middle Aged; D057873:Peri-Implantitis / Q000188:drug therapy* / Q000628:therapy*; D057747:Periodontal Debridement / Q000295:instrumentation* / Q000379:methods*; D010512:Periodontal Index; D011446:Prospective Studies; D016037:Single-Blind Method; D018709:Statistics, Nonparametric; D055815:Young Adult
chemical_list: D000891:Anti-Infective Agents, Local; D015921:Dental Implants; D002710:Chlorhexidine; D005998:Glycine