title: Hot-injection synthesis of iron/iron oxide core/shell nanoparticles for T2 contrast enhancement in magnetic resonance imaging.
abstract: Here we report a new, bench-top synthesis for iron/iron oxide core/shell nanoparticles via the thermal decomposition of Fe(η(5)-C(6)H(3)Me(4))(2). The iron/iron oxide core/shell nanoparticles are superparamagnetic at room temperature and show improved negative contrast in T(2)-weighted MR imaging compared to pure iron oxides nanoparticles, and have a transverse relaxivity (r(2)) of 332 mM(-1) s(-1).
authors.affiliation: School of Chemical and Physical Sciences and The MacDiarmid Institute of Advanced Materials and Nanotechnology, Victoria University of Wellington, P.O. Box 600, Wellington, New Zealand.
authors.forename: David A J
authors.initials: DA
authors.lastname: Herman
authors.forename: Peter
authors.initials: P
authors.lastname: Ferguson
authors.forename: Soshan
authors.initials: S
authors.lastname: Cheong
authors.forename: Ian F
authors.initials: IF
authors.lastname: Hermans
authors.forename: Ben J
authors.initials: BJ
authors.lastname: Ruck
authors.forename: Kathryn M
authors.initials: KM
authors.lastname: Allan
authors.forename: Sujay
authors.initials: S
authors.lastname: Prabakar
authors.forename: John L
authors.initials: JL
authors.lastname: Spencer
authors.forename: Conrad D
authors.initials: CD
authors.lastname: Lendrum
authors.forename: Richard D
authors.initials: RD
authors.lastname: Tilley
mesh_terms: D003287:Contrast Media / Q000138:chemical synthesis* / Q000737:chemistry; D005290:Ferric Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D006358:Hot Temperature; D008279:Magnetic Resonance Imaging / Q000379:methods; D053758:Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D036103:Nanotechnology / Q000379:methods
chemical_list: D003287:Contrast Media; D005290:Ferric Compounds; C000499:ferric oxide