title: Rab GTPases and tethering in the yeast endocytic pathway.
abstract: Within eukaryotic cells, Rab GTPases control the maturation of early to late endosomes and their subsequent fusion with the vacuole. Within this ExtraView, we will focus on our recent findings regarding the activation of the Rab7 homolog Ypt7 in yeast and its interplay with the two multisubunit tethering complexes CORVET and HOPS.
authors.affiliation: Department of Biology/Chemistry; Biochemistry Section; University of Osnabrück; Osnabrück, Germany.
authors.forename: Jens
authors.initials: J
authors.lastname: Lachmann
authors.forename: Christian
authors.initials: C
authors.lastname: Ungermann
authors.forename: Siegfried
authors.initials: S
authors.lastname: Engelbrecht-Vandré