title: [Risk factors of contrast-induced nephropathy after percutaneous coronary intervention in patients with coronary heart disease and the countermeasures].
abstract: OBJECTIVE
  To identify the risk factors of contrast-induced nephropathy (CIN) after coronary interventional therapy (PCI) in patients with coronary heart disease and analyze the clinical outcomes and the preventive measures of CIN.
  
  
  METHODS
  Ninety-one patients who developed CIN after PCI were retrospectively analyzed to identify the risk factors and explore the preventive measures.
  
  
  RESULTS
  CIN was strongly associated with pre-procedural chronic renal failure, diabetes mellitus and administration of large-dose contrast. The incidence of cardiac mortality in hospital or in the follow-up at one year after PCI, and the incidence of myocardial infarction or major adverse cardiac events in the follow-up at one year were obviously higher in patients with CIN than those without CIN.
  
  
  CONCLUSIONS
  Chronic renal failure, diabetes mellitus and large-dose contrast administration are 3 independent risk factors of CIN, which affects the prognosis of the patients. Reinforcement of a comprehensive perioperative management of PCI, especially a rigorous preoperative preparation, can be an important strategy for prevention of CIN.
authors.affiliation: Department of Cardiology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China. gzhzmd@fimmu.com
authors.forename: Hua
authors.initials: H
authors.lastname: Zheng
authors.forename: Yan
authors.initials: Y
authors.lastname: Tu
authors.forename: Li-qin
authors.initials: LQ
authors.lastname: Ma
mesh_terms: D000368:Aged; D002681:China / Q000453:epidemiology; D003287:Contrast Media / Q000009:adverse effects*; D003327:Coronary Disease / Q000628:therapy*; D005260:Female; D006801:Humans; D007674:Kidney Diseases / Q000139:chemically induced* / Q000453:epidemiology / Q000517:prevention & control*; D008297:Male; D008875:Middle Aged; D062645:Percutaneous Coronary Intervention / Q000009:adverse effects*; D012189:Retrospective Studies; D012307:Risk Factors
chemical_list: D003287:Contrast Media