title: Critical appraisal of ophthalmic ketorolac in treatment of pain and inflammation following cataract surgery.
abstract: BACKGROUND
  The purpose of this review was to provide a critical appraisal of the literature supporting the efficacy of ophthalmic ketorolac (Acuvail(®)) in the treatment of pain and inflammation after cataract surgery.
  
  
  METHODS
  Literature search and expert opinion of the authors.
  
  
  RESULTS
  Recent studies indicate greater intraocular drug levels in the anterior chamber and iris-ciliary body after topical application of Acuvail in comparison with older formulations of ketorolac. A large randomized, multicenter, placebo-controlled study demonstrated significantly less inflammation and pain after cataract surgery using Acuvail.
  
  
  CONCLUSIONS
  Acuvail appears to be effective in reducing post-cataract surgery pain and inflammation.
authors.affiliation: Department of Ophthalmology, Vanderbilt University, Nashville, TN, USA.
authors.forename: Rahul
authors.initials: R
authors.lastname: Reddy
authors.forename: Stephen Jae
authors.initials: SJ
authors.lastname: Kim