title: Thermally induced cycloadditions of donor/acceptor carbenes.
abstract: The thermal decomposition of aryldiazoacetates and aryldiazoketones in the absence of a catalyst leads to synthetically useful transformations. The thermal reaction of aryldiazoacetates with alkenes generates cyclopropanes in 68-97% yield and with good diastereoselectivity (up to 19:1 dr) when the aryl substituent is electron-rich. The thermal reaction of aryldiazoketones with alkenes generated cyclobutanones in 71-94% yield and with good diastereocontrol (≥9:1 dr).
authors.affiliation: Emory University, Department of Chemistry, 1515 Dickey Drive, Atlanta, Georgia 30322, USA.
authors.forename: Stephanie R
authors.initials: SR
authors.lastname: Ovalles
authors.forename: Jørn H
authors.initials: JH
authors.lastname: Hansen
authors.forename: Huw M L
authors.initials: HM
authors.lastname: Davies