title: Empiric antimicrobial therapy for Gram-negative sepsis: back to the future.
authors.forename: Surbhi
authors.initials: S
authors.lastname: Leekha
authors.forename: Harold C
authors.initials: HC
authors.lastname: Standiford
mesh_terms: D000617:Aminoglycosides / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D016470:Bacteremia / Q000188:drug therapy* / Q000382:microbiology; D003422:Critical Care / Q000379:methods; D016638:Critical Illness / Q000401:mortality / Q000628:therapy; D004359:Drug Therapy, Combination; D036262:Empirical Research; D005260:Female; D005544:Forecasting; D006090:Gram-Negative Bacteria / Q000187:drug effects* / Q000302:isolation & purification; D016905:Gram-Negative Bacterial Infections / Q000175:diagnosis / Q000188:drug therapy*; D006801:Humans; D017053:Infection Control / Q000639:trends; D007362:Intensive Care Units; D008297:Male; D011113:Polymyxins / Q000627:therapeutic use; D018805:Sepsis / Q000188:drug therapy / Q000382:microbiology; D016896:Treatment Outcome
chemical_list: D000617:Aminoglycosides; D000900:Anti-Bacterial Agents; D011113:Polymyxins