title: Colchicine-sensitive nephrotic syndrome due to AA amyloidosis.
abstract: A 28-year-old women is presented who was evaluated for a new-onset postpartum nephrotic syndrome with normal renal function. Histological diagnosis was AA amyloidosis but no underlying disease has been diagnosed despite extensive workup. Complete remission was achieved with colchicine. Upon discontinuation of colchicines, the patient's nephrotic syndrome flared up but completely responded to reinstitution of colchicine therapy. Remission of this patient's nephrotic syndrome is thus not attributable to resolution of any "idiopathic" primary disease.
authors.affiliation: Department of Nephrology, Soroka Medical Center and Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel. hausmann@bgu.ac.il
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Hausmann
authors.forename: Esther
authors.initials: E
authors.lastname: Maor
authors.forename: Leonid
authors.initials: L
authors.lastname: Kachko
mesh_terms: D000328:Adult; D000686:Amyloidosis / Q000188:drug therapy* / Q000378:metabolism / Q000473:pathology; D003078:Colchicine / Q000008:administration & dosage / Q000627:therapeutic use*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D009404:Nephrotic Syndrome / Q000188:drug therapy* / Q000378:metabolism / Q000473:pathology; D049590:Postpartum Period; D011247:Pregnancy; D000685:Serum Amyloid A Protein / Q000378:metabolism*; D016896:Treatment Outcome
chemical_list: D000685:Serum Amyloid A Protein; D003078:Colchicine