title: Competing for the clamp: promoting RNA polymerase processivity and managing the transition from initiation to elongation.
abstract: Transcription elongation factor NusG/Spt5 spans the central cleft of RNA polymerase and functionally competes with transcription initiation factors. This work highlights the RNA polymerase clamp as a target for regulation and points to dynamic interactions between initiation and elongation machineries.
authors.affiliation: Department of Molecular, Cell and Developmental Biology, University of California, Santa Cruz, CA 95064, USA. hartzog@biology.ucsc.edu
authors.forename: Grant A
authors.initials: GA
authors.lastname: Hartzog
authors.forename: Craig D
authors.initials: CD
authors.lastname: Kaplan