title: Asian lineage of peste des petits ruminants virus, Africa.
abstract: Interest in peste des petits ruminants virus (PPRV) has been stimulated by recent changes in its host and geographic distribution. For this study, biological specimens were collected from camels, sheep, and goats clinically suspected of having PPRV infection in Sudan during 2000-2009 and from sheep soon after the first reported outbreaks in Morocco in 2008. Reverse transcription PCR analysis confirmed the wide distribution of PPRV throughout Sudan and spread of the virus in Morocco. Molecular typing of 32 samples positive for PPRV provided strong evidence of the introduction and broad spread of Asian lineage IV. This lineage was defined further by 2 subclusters; one consisted of camel and goat isolates and some of the sheep isolates, while the other contained only sheep isolates, a finding with suggests a genetic bias according to the host. This study provides evidence of the recent spread of PPRV lineage IV in Africa.
authors.affiliation: Control of Exotic and Emerging Animal Diseases, Montpellier, France.
authors.forename: Olivier
authors.initials: O
authors.lastname: Kwiatek
authors.forename: Yahia Hassan
authors.initials: YH
authors.lastname: Ali
authors.forename: Intisar Kamil
authors.initials: IK
authors.lastname: Saeed
authors.forename: Abdelmelik Ibrahim
authors.initials: AI
authors.lastname: Khalafalla
authors.forename: Osama Ishag
authors.initials: OI
authors.lastname: Mohamed
authors.forename: Ali Abu
authors.initials: AA
authors.lastname: Obeida
authors.forename: Magdi Badawi
authors.initials: MB
authors.lastname: Abdelrahman
authors.forename: Halima Mohamed
authors.initials: HM
authors.lastname: Osman
authors.forename: Khalid Mohamed
authors.initials: KM
authors.lastname: Taha
authors.forename: Zakia
authors.initials: Z
authors.lastname: Abbas
authors.forename: Mehdi
authors.initials: M
authors.lastname: El Harrak
authors.forename: Youssef
authors.initials: Y
authors.lastname: Lhor
authors.forename: Adama
authors.initials: A
authors.lastname: Diallo
authors.forename: Renaud
authors.initials: R
authors.lastname: Lancelot
authors.forename: Emmanuel
authors.initials: E
authors.lastname: Albina
authors.forename: Genevieve
authors.initials: G
authors.lastname: Libeau
mesh_terms: D000818:Animals; D000956:Antigens, Viral / Q000032:analysis; D002162:Camelus; D016000:Cluster Analysis; D004196:Disease Outbreaks; D004797:Enzyme-Linked Immunosorbent Assay; D015511:Goat Diseases / Q000453:epidemiology / Q000235:genetics / Q000821:virology*; D006041:Goats; D008137:Longitudinal Studies; D058889:Molecular Typing; D009018:Morocco; D029021:Peste-des-Petits-Ruminants / Q000453:epidemiology / Q000662:veterinary* / Q000821:virology; D018107:Peste-des-petits-ruminants virus / Q000235:genetics / Q000302:isolation & purification / Q000472:pathogenicity; D010802:Phylogeny; D058974:Phylogeography; D020133:Reverse Transcriptase Polymerase Chain Reaction; D012756:Sheep; D012757:Sheep Diseases / Q000453:epidemiology / Q000235:genetics / Q000821:virology*; D013397:Sudan
chemical_list: D000956:Antigens, Viral