title: Crystallographic recognition controls peptide binding for bio-based nanomaterials.
abstract: The ability to control the size, shape, composition, and activity of nanomaterials presents a formidable challenge. Peptide approaches represent new avenues to achieve such control at the synthetic level; however, the critical interactions at the bio/nano interface that direct such precision remain poorly understood. Here we present evidence to suggest that materials-directing peptides bind at specific time points during Pd nanoparticle (NP) growth, dictated by material crystallinity. As such surfaces are presented, rapid peptide binding occurs, resulting in the stabilization and size control of single-crystal NPs. Such specificity suggests that peptides could be engineered to direct the structure of nanomaterials at the atomic level, thus enhancing their activity.
authors.affiliation: Department of Chemistry, University of Miami, Coral Gables, Florida 33124, United States.
authors.forename: Ryan
authors.initials: R
authors.lastname: Coppage
authors.forename: Joseph M
authors.initials: JM
authors.lastname: Slocik
authors.forename: Beverly D
authors.initials: BD
authors.lastname: Briggs
authors.forename: Anatoly I
authors.initials: AI
authors.lastname: Frenkel
authors.forename: Hendrik
authors.initials: H
authors.lastname: Heinz
authors.forename: Rajesh R
authors.initials: RR
authors.lastname: Naik
authors.forename: Marc R
authors.initials: MR
authors.lastname: Knecht
mesh_terms: D001665:Binding Sites; D003460:Crystallization; D056004:Molecular Dynamics Simulation; D053758:Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D010165:Palladium / Q000737:chemistry*; D010316:Particle Size; D010455:Peptides / Q000737:chemistry*; D011485:Protein Binding; D013499:Surface Properties
chemical_list: D010455:Peptides; D010165:Palladium