title: Rapid screening for pesticides using automated online sample preparation with a high-resolution benchtop Orbitrap mass spectrometer.
abstract: For pesticide analysis in food products a common approach is to develop a fast multi-residue method that is capable of identifying and quantifying a large number of analytes in various matrices. This study demonstrates rapid screening and accurate mass confirmation of 116 pesticides in oranges and hazelnuts using an automated online sample preparation method with turbulent-flow chromatography technology coupled to a high-resolution benchtop Orbitrap™ mass spectrometer. The limits of quantification (LOQs) for the majority of analytes are well below the maximum residue limit (MRL) set by the European Union and the Japanese government. The recoveries were in the range of 70-120% for over 75% of analytes in both matrices. The present methodology is suitable for routine pesticides analysis in food safety laboratories.
authors.affiliation: Thermo Fisher Scientific, Franklin, MA 02038, USA. yang.shi@thermofisher.com
authors.forename: Y
authors.initials: Y
authors.lastname: Shi
authors.forename: J S
authors.initials: JS
authors.lastname: Chang
authors.forename: C L
authors.initials: CL
authors.lastname: Esposito
authors.forename: C
authors.initials: C
authors.lastname: Lafontaine
authors.forename: M J
authors.initials: MJ
authors.lastname: Berube
authors.forename: J A
authors.initials: JA
authors.lastname: Fink
authors.forename: F A
authors.initials: FA
authors.lastname: Espourteille
mesh_terms: D001331:Automation; D057230:Limit of Detection; D013058:Mass Spectrometry / Q000295:instrumentation / Q000379:methods*; D010573:Pesticide Residues / Q000032:analysis*; D015203:Reproducibility of Results
chemical_list: D010573:Pesticide Residues