title: Clinical outcome of levonorgestrel intra-uterine system in idiopathic menorrhagia.
abstract: OBJECTIVE
  To evaluate the efficacy, acceptability and side effects of levonorgestrel intrauterine system in patients with idiopathic menorrhagia.
  
  
  METHODS
  A prospective, non-randomized clinical study in which 42 women between the age of 35-55 years complaining of menorrhagia with or without irregular cycle were recruited during one year period. The women were followed up at 3, 6, 12, 24 and 36 months after insertion.
  
  
  RESULTS
  The reduction in mean blood loss was found to be statistically significant with a p value of < 0.001 for all the follow-up periods.
  
  
  CONCLUSIONS
  The present study projects levonorgestrel intrauterine system as an effective patient friendly device with a high degree of compliance and worth considering as a viable alternative to surgery for the management of menorrhagia due to dysfunctional uterine bleeding in developing countries like India.
authors.affiliation: Department of Obstetrics and Gynaecology, Lady Hardinge Medical College, New Delhi, India.
authors.forename: B
authors.initials: B
authors.lastname: Chattopdhyay
authors.forename: A
authors.initials: A
authors.lastname: Nigam
authors.forename: S
authors.initials: S
authors.lastname: Goswami
authors.forename: P S
authors.initials: PS
authors.lastname: Chakravarty
mesh_terms: D000282:Administration, Intravaginal; D000328:Adult; D015415:Biomarkers / Q000097:blood; D016009:Chi-Square Distribution; D003271:Contraceptive Agents, Female / Q000008:administration & dosage* / Q000009:adverse effects; D003906:Developing Countries; D005260:Female; D006454:Hemoglobins / Q000378:metabolism; D006801:Humans; D007194:India; D007436:Intrauterine Devices, Medicated; D016912:Levonorgestrel / Q000008:administration & dosage* / Q000009:adverse effects; D008595:Menorrhagia / Q000097:blood / Q000188:drug therapy* / Q000503:physiopathology; D008598:Menstruation / Q000187:drug effects*; D008875:Middle Aged; D017060:Patient Satisfaction; D011446:Prospective Studies; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D015415:Biomarkers; D003271:Contraceptive Agents, Female; D006454:Hemoglobins; D016912:Levonorgestrel