title: IRiS: construction of ARG networks at genomic scales.
abstract: CONCLUSIONS
  Given a set of extant haplotypes IRiS first detects high confidence recombination events in their shared genealogy. Next using the local sequence topology defined by each detected event, it integrates these recombinations into an ancestral recombination graph. While the current system has been calibrated for human population data, it is easily extendible to other species as well.
  
  
  BACKGROUND
  IRiS (Identification of Recombinations in Sequences) binary files are available for non-commercial use in both Linux and Microsoft Windows, 32 and 64 bit environments from https://researcher.ibm.com/researcher/view_project.php?id = 2303
  
  
  BACKGROUND
  parida@us.ibm.com.
authors.affiliation: Computational Biology Center, IBM T J Watson Research, Yorktown Heights, NY 10598, USA.
authors.forename: Asif
authors.initials: A
authors.lastname: Javed
authors.forename: Marc
authors.initials: M
authors.lastname: Pybus
authors.forename: Marta
authors.initials: M
authors.lastname: Melé
authors.forename: Filippo
authors.initials: F
authors.lastname: Utro
authors.forename: Jaume
authors.initials: J
authors.lastname: Bertranpetit
authors.forename: Francesc
authors.initials: F
authors.lastname: Calafell
authors.forename: Laxmi
authors.initials: L
authors.lastname: Parida
mesh_terms: D000465:Algorithms; D015894:Genome, Human; D023281:Genomics; D006239:Haplotypes; D006801:Humans; D008957:Models, Genetic; D011995:Recombination, Genetic; D012984:Software