title: DDQ-promoted dehydrogenation from natural rigid polycyclic acids or flexible alkyl acids to generate lactones by a radical ion mechanism.
abstract: A novel and facile DDQ-mediated dehydrogenation from natural rigid polycyclic acids or flexible alkyl acids to generate lactones is described. The formation of lactones proceeds by a radical ion mechanism, which has been established by DPPH˙-mediated chemical identification, ESR spectroscopy and an enol intermediate trapping.
authors.affiliation: Center of Drug Discovery, China Pharmaceutical University, Nanjing 210009, China.
authors.forename: Ye
authors.initials: Y
authors.lastname: Ding
authors.forename: Zhangjian
authors.initials: Z
authors.lastname: Huang
authors.forename: Jian
authors.initials: J
authors.lastname: Yin
authors.forename: Yisheng
authors.initials: Y
authors.lastname: Lai
authors.forename: Shibo
authors.initials: S
authors.lastname: Zhang
authors.forename: Zhiguo
authors.initials: Z
authors.lastname: Zhang
authors.forename: Lei
authors.initials: L
authors.lastname: Fang
authors.forename: Sixun
authors.initials: S
authors.lastname: Peng
authors.forename: Yihua
authors.initials: Y
authors.lastname: Zhang
mesh_terms: D016227:Benzoquinones / Q000737:chemistry*; D001713:Biphenyl Compounds / Q000737:chemistry; D005609:Free Radicals / Q000737:chemistry; D007477:Ions / Q000737:chemistry; D007783:Lactones / Q000138:chemical synthesis / Q000737:chemistry*; D009828:Oleanolic Acid / Q000031:analogs & derivatives / Q000737:chemistry*; D010851:Picrates / Q000737:chemistry
chemical_list: C116817:2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid; D016227:Benzoquinones; D001713:Biphenyl Compounds; D005609:Free Radicals; D007477:Ions; D007783:Lactones; D010851:Picrates; C000928:dichlorodicyanobenzoquinone; D009828:Oleanolic Acid; C004931:1,1-diphenyl-2-picrylhydrazyl