title: Upper gastrointestinal bleeding in an end-stage renal disease patient treated with fluoxetine.
abstract: The defective platelets of end-stage renal disease patients might be further incapacitated by the antiplatelet effect of selective serotonin reuptake inhibitor, and bleeding tendency in these patients could be aggravated. Here we demonstrate an end-stage renal disease patient who was admitted for duodenal ulcer bleeding during the treatment with fluoxetine, and the bleeding did not stop by various active treatments until the cessation of fluoxetine.
authors.affiliation: Department of Psychiatry, Shin Kong Wu Ho-Su Memorial Hospital, Taipei City 111, Taiwan (R.O.C.). paneth@mail2000.com.tw
authors.forename: Chia-Ta
authors.initials: CT
authors.lastname: Chan
authors.forename: Sidney S
authors.initials: SS
authors.lastname: Chang
authors.forename: Eng-Kung
authors.initials: EK
authors.lastname: Yeh
authors.forename: Lih-Chih
authors.initials: LC
authors.lastname: Jou
mesh_terms: D000368:Aged; D001714:Bipolar Disorder / Q000150:complications* / Q000188:drug therapy*; D004381:Duodenal Ulcer; D005473:Fluoxetine / Q000009:adverse effects* / Q000627:therapeutic use; D006471:Gastrointestinal Hemorrhage / Q000139:chemically induced; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications; D008297:Male; D010438:Peptic Ulcer Hemorrhage / Q000139:chemically induced* / Q000628:therapy; D017367:Selective Serotonin Reuptake Inhibitors / Q000009:adverse effects* / Q000627:therapeutic use; D016896:Treatment Outcome
chemical_list: D005473:Fluoxetine; D017367:Selective Serotonin Reuptake Inhibitors