title: Comparison of apatite-coated titanium prepared by blast coating and flame spray methods--evaluation using simulated body fluid and initial histological study.
abstract: It has previously been demonstrated that apatite may be coated on the surface of titanium (Ti) at room temperature when the titanium is blasted with apatite powder. This method is known as the blast coating (BC) method. In this study, the osteoconductivity and tissue response to Ti implants blast-coated with apatite (BC implants) were evaluated using apatite-coated Ti implants produced using the flame spraying (FS) method (FS implants) and pure Ti implants as a control. Initial evaluation using simulated body fluid demonstrated higher osteoconductivity in BC implants than in FS implants. Therefore, specimens were implanted in rat tibias for 1, 3 and 6 weeks. At one week after implantation, BC implants showed much higher bone contact ratio when compared with FS implants; the bone contact ratio of BC implants was 75.7%, while the FS and pure Ti implants had ratios of 30.8% and 5.5%, respectively. The difference in bone contact ratio between BC and FS implants decreased with implantation time and the ratios were equal after 6 weeks. In conclusion, BC implants show higher osteoconductivity than FS implants, and thus BC implants are beneficial for early fixation of implants to bone tissue.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Yamaguchi University Graduate School of Medicine, 1-1-1 Minamikogushi, Ube, Japan. tmano@yamaguchi-u.ac.jp
authors.forename: Takamitsu
authors.initials: T
authors.lastname: Mano
authors.forename: Kunio
authors.initials: K
authors.lastname: Ishikawa
authors.forename: Koji
authors.initials: K
authors.lastname: Harada
authors.forename: Hirotsugu
authors.initials: H
authors.lastname: Umeda
authors.forename: Yoshiya
authors.initials: Y
authors.lastname: Ueyama
mesh_terms: D000818:Animals; D001031:Apatites / Q000737:chemistry*; D002021:Buffers; D002122:Calcium Chloride / Q000737:chemistry; D020099:Coated Materials, Biocompatible / Q000737:chemistry*; D045662:Dental Etching / Q000379:methods*; D015921:Dental Implants; D003764:Dental Materials / Q000737:chemistry*; D015636:Magnesium Chloride / Q000737:chemistry; D008297:Male; D008855:Microscopy, Electron, Scanning; D016348:Osseointegration / Q000502:physiology; D010012:Osteogenesis / Q000502:physiology; D010710:Phosphates / Q000737:chemistry; D011189:Potassium Chloride / Q000737:chemistry; D017680:Potassium Compounds / Q000737:chemistry; D051381:Rats; D017208:Rats, Wistar; D017693:Sodium Bicarbonate / Q000737:chemistry; D012965:Sodium Chloride / Q000737:chemistry; D013053:Spectrophotometry; D017550:Spectroscopy, Fourier Transform Infrared; D013499:Surface Properties; D013696:Temperature; D013977:Tibia / Q000473:pathology / Q000601:surgery; D013997:Time Factors; D014025:Titanium / Q000737:chemistry*; D014961:X-Ray Diffraction
chemical_list: D001031:Apatites; D002021:Buffers; D020099:Coated Materials, Biocompatible; D015921:Dental Implants; D003764:Dental Materials; D010710:Phosphates; D017680:Potassium Compounds; D015636:Magnesium Chloride; D012965:Sodium Chloride; D011189:Potassium Chloride; D017693:Sodium Bicarbonate; C013216:potassium phosphate; D014025:Titanium; D002122:Calcium Chloride