title: Renal anomalies associated with ectopic neurohypophysis.
abstract: OBJECTIVE
  Although the etiology of ectopic neurohypophysis that leads to pituitary hormone deficiencies is not yet clearly understood, birth trauma or genetic factors have been considered responsible. Concurrent cranial and extracranial congenital anomalies have been reported in such cases. The aim of the present study was to investigate the frequency of renal anomalies in nonsyndromic cases with ectopic neurohypophysis.
  
  
  METHODS
  We retrospectively evaluated the medical records of 20 patients with ectopic neurohypophysis who were followed up between January 1990 and December 2007 in a tertiary University Hospital.
  
  
  RESULTS
  Renal anomalies were identified in three (15%) cases including unilateral renal agenesis in one case, renal hypoplasia in one case, and double collecting system and unilateral renal agenesis in one case.
  
  
  CONCLUSIONS
  In the present study, the increased frequency of renal anomalies in cases of ectopic neurohypophysis was highlighted, and it was emphasized that there might be common genetic factors that lead to such associations.
authors.affiliation: Pediatric Endocrinology Unit, Mersin Children Hospital, Toroslar, Mersin, Turkey. samimozen@gmail.com
authors.forename: Samim
authors.initials: S
authors.lastname: Özen
authors.forename: Damla Gökşen
authors.initials: DG
authors.lastname: Şişmek
authors.forename: Asan
authors.initials: A
authors.lastname: Önder
authors.forename: Şükran
authors.initials: Ş
authors.lastname: Darcan
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D002828:Choristoma / Q000150:complications; D000013:Congenital Abnormalities; D005260:Female; D019382:Human Growth Hormone / Q000172:deficiency; D006801:Humans; D007223:Infant; D007668:Kidney / Q000002:abnormalities*; D007674:Kidney Diseases / Q000150:complications / Q000151:congenital; D008297:Male; D010904:Pituitary Gland, Posterior; D010908:Pituitary Hormones, Anterior / Q000172:deficiency; D012189:Retrospective Studies
chemical_list: D010908:Pituitary Hormones, Anterior; D019382:Human Growth Hormone