title: An in vitro evaluation of the anthelmintic activity of Hedychium spichatum rhizomes and Zingiber zerumbet rhizomes on the Pheritima Posthuma model: A comparative study.
abstract: Ethanolic extracts of Hedychium spichatum rhizomes and Zingiber zerumbet rhizomes were taken for in vitro comparative studies on the anthelmintic activity against Pheritima posthuma. Different concentrations (25, 50, 100 mg/ml) of both the extracts were used for the activity. Varying albendazole concentrations (25, 50, 100 mg/ml) were used as a reference standard and normal saline (0.9% NaCl) was used for the control treatment. The results were expressed in terms of time in minutes to report the paralysis and time of death of the earthworms. The results obtained from the study indicate toward the anthelmintic activity, supporting folk use of both the plants when compared with the standard. The results also established that Z. zerumbet was a more potent candidature of as compared with H. spichatum.
authors.affiliation: Department of Pharmacy, Institute of Technology and Management, Gorakhpur, India.
authors.forename: Shambaditya
authors.initials: S
authors.lastname: Goswami
authors.forename: Awanish
authors.initials: A
authors.lastname: Pandey
authors.forename: Poonam
authors.initials: P
authors.lastname: Tripathi
authors.forename: Asheesh
authors.initials: A
authors.lastname: Singh
authors.forename: Amrita
authors.initials: A
authors.lastname: Rai