title: [A case of metastatic esophageal cancer - endoscopic resection of the primary site following systemic chemotherapies].
abstract: A 64-year-old male presented with discomfort in the chest. His endoscopic examination and CT scan showed esophageal cancer with multiple liver metastases. A total of ten courses of systemic chemotherapy by 5-fluorouracil (5-FU) (800 mg for five days) and cisplatin (CDDP) (80 mg/day on the first day of the week for four weeks) were performed, and liver and lymph node metastases disappeared. The primary lesion was the only site detected positive by PET scan. After a concurrent chemoradiation therapy, salvage endoscopic mucosal resection (EMR) was performed on the remainder of the primary site and the patient gained a complete response (CR). We report this case because, although the mean survival time of advanced esophageal cancer is less than one year, this patient responded to chemotherapy and gained complete response by salvage EMR. This patient has had no recurrence for four years since his initial diagnosis.
authors.affiliation: Dept. of Gastroenterology and Hepatology, Keio University, Japan.
authors.forename: Motoko
authors.initials: M
authors.lastname: Izumiya
authors.forename: Yoshiyuki
authors.initials: Y
authors.lastname: Yamagishi
authors.forename: Shouko
authors.initials: S
authors.lastname: Nakamura
authors.forename: Gen
authors.initials: G
authors.lastname: Sakai
authors.forename: Shinsuke
authors.initials: S
authors.lastname: Funakoshi
authors.forename: Masayuki
authors.initials: M
authors.lastname: Adachi
authors.forename: Hajime
authors.initials: H
authors.lastname: Higuchi
authors.forename: Hiromasa
authors.initials: H
authors.lastname: Takaishi
authors.forename: Jin
authors.initials: J
authors.lastname: Sugiura
authors.forename: Eri
authors.initials: E
authors.lastname: Irie
authors.forename: Tai
authors.initials: T
authors.lastname: Ohmori
authors.forename: Toshifumi
authors.initials: T
authors.lastname: Hibi
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002945:Cisplatin / Q000008:administration & dosage / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D004724:Endoscopy; D004938:Esophageal Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D005472:Fluorouracil / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000556:secondary; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D049268:Positron-Emission Tomography; D014057:Tomography, X-Ray Computed
chemical_list: D002945:Cisplatin; D005472:Fluorouracil