title: Why are multi-centre clinical observational studies still so difficult to run?
abstract: Despite the introduction of IRAS, obtaining R&D approvals for multicentre studies is a major rate limiting step. Our experience with cleft research demonstrates that this approvals process must be drastically and rapidly improved if we wish to continue attract clinical research to the UK.
authors.affiliation: School of Oral & Dental Sciences, University of Bristol, Bristol, UK. jonathan.sandy@bristol.ac.uk
authors.forename: J
authors.initials: J
authors.lastname: Sandy
authors.forename: N
authors.initials: N
authors.lastname: Kilpatrick
authors.forename: M
authors.initials: M
authors.lastname: Persson
authors.forename: A
authors.initials: A
authors.lastname: Bessel
authors.forename: A
authors.initials: A
authors.lastname: Waylen
authors.forename: A
authors.initials: A
authors.lastname: Ness
authors.forename: A
authors.initials: A
authors.lastname: Ireland
mesh_terms: D002971:Cleft Lip / Q000628:therapy; D002972:Cleft Palate / Q000628:therapy; D054976:Clinical Governance; D002986:Clinical Trials as Topic; D032982:Contracts; D018865:Dental Research; D032984:Ethics, Research; D005568:Forms and Records Control; D006258:Head and Neck Neoplasms / Q000628:therapy; D006801:Humans; D015337:Multicenter Studies as Topic; D009862:Online Systems; D010043:Outcome and Process Assessment, Health Care; D010348:Patient Care Team; D012107:Research Design; D012108:Research Personnel; D012109:Research Support as Topic; D013218:State Dentistry; D013997:Time Factors; D006113:United Kingdom