title: Serum myeloperoxidase and adenosine deaminase activities in polycystic ovary syndrome.
abstract: OBJECTIVE
  To evaluate serum myeloperoxidase (MPO) and adenosine deaminase activities and to investigate whether there was a correlation between these and sex hormones, and lipids in polycystic ovary syndrome.
  
  
  METHODS
  Forty-five women with polycystic ovary syndrome and 40 healthy controls were included in this study. Leukocyte counts, serum MPO and adenosine deaminase activities, and high-sensitive C-reactive protein (hs-CRP), sex hormone and lipid levels were assessed.
  
  
  RESULTS
  Leukocyte counts and serum MPO activities were higher (p < 0.01 and p < 0.05, respectively) and there was a significant correlation between serum adenosine deaminase and hs-CRP level in women with polycystic ovary syndrome (r = 0.853, p < 0.01). Serum MPO and adenosine deaminase levels did not correlate with sex hormones or lipid profiles in these patients.
  
  
  CONCLUSIONS
  Polycystic ovary syndrome may involve an inflammatory process by increasing serum MPO activity independent of sex hormones, body mass index and lipid profiles.
authors.affiliation: Department of Obstetrics and Gynecology, Faculty of Medicine, Yuzuncu Yil University, Van, Turkey. zehrakurdoglu@hotmail.com
authors.forename: Zehra
authors.initials: Z
authors.lastname: Kurdoglu
authors.forename: Halil
authors.initials: H
authors.lastname: Ozkol
authors.forename: Mertihan
authors.initials: M
authors.lastname: Kurdoglu
mesh_terms: D000243:Adenosine Deaminase / Q000378:metabolism*; D000293:Adolescent; D015992:Body Mass Index; D002097:C-Reactive Protein / Q000032:analysis; D005260:Female; D012739:Gonadal Steroid Hormones / Q000097:blood; D006801:Humans; D008055:Lipids / Q000097:blood; D009195:Peroxidase / Q000097:blood / Q000378:metabolism*; D011085:Polycystic Ovary Syndrome / Q000097:blood / Q000378:metabolism*; D055815:Young Adult
chemical_list: D012739:Gonadal Steroid Hormones; D008055:Lipids; D002097:C-Reactive Protein; D009195:Peroxidase; D000243:Adenosine Deaminase