title: [Eighty-five-year-old patient with recurrent rectal cancer effectively treated with CapeOX chemotherapy].
abstract: We report a case of a super-elderly patient with recurrent rectal cancer effectively treated with CapeOX chemotherapy. A 85-year-old man who had a low anterior resection was diagnosed with rectal cancer in July 2009. Although peritoneal dissemination near the main tumor was disclosed during the operation, a R0 and Cur B operation was performed. After the operation, an elevation of tumor markers was detected in October. A chest-abdominal-pelvic CT scan revealed multiple liver metastases of the bilateral lobe and a metastasis of the right iliac bone. We attempted CapeOX chemotherapy from November. After 3 courses of CapeOX chemotherapy, the multiple liver metastases shrank and the bone metastasis changed to a consolidation. Although grade 1 chronic peripheral neuropathy appeared after 8 courses of chemotherapy, no other adverse event appeared. After 10 courses of CapeOX chemotherapy, the chemotherapy was changed to capecitabine at the patient's request. A chest-abdominal-pelvic CT scan after 10 courses of CapeOX chemotherapy revealed that the multiple liver metastases were shrinking. As of September 2010, the patient's PS score is 0, and he has been under treatment as an outpatient.
authors.affiliation: Dept. of Surgery, Sado General Hospital, Nagaoka Red Cross Hospital, Japan.
authors.forename: Yoshifumi
authors.initials: Y
authors.lastname: Shimada
authors.forename: Takeya
authors.initials: T
authors.lastname: Sakamoto
authors.forename: Manabu
authors.initials: M
authors.lastname: Oyamatsu
authors.forename: Kenji
authors.initials: K
authors.lastname: Sato
authors.forename: Tatsuo
authors.initials: T
authors.lastname: Tani
mesh_terms: D000369:Aged, 80 and over; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001859:Bone Neoplasms / Q000188:drug therapy / Q000556:secondary; D000069287:Capecitabine; D003841:Deoxycytidine / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D005472:Fluorouracil / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D006801:Humans; D008113:Liver Neoplasms / Q000188:drug therapy / Q000556:secondary; D008297:Male; D009944:Organoplatinum Compounds / Q000008:administration & dosage / Q000627:therapeutic use*; D000077150:Oxaliplatin; D012004:Rectal Neoplasms / Q000188:drug therapy* / Q000473:pathology; D012008:Recurrence; D014057:Tomography, X-Ray Computed
chemical_list: D009944:Organoplatinum Compounds; D000077150:Oxaliplatin; D003841:Deoxycytidine; D000069287:Capecitabine; D005472:Fluorouracil