title: Point-of-care urine trypsinogen-2 test for diagnosis of acute pancreatitis.
abstract: OBJECTIVE
  To assess a point-of-care urine trypsinogen-2 (UT) test for the diagnosis of acute pancreatitis.
  
  
  METHODS
  This was a prospective study of patients presenting to the emergency department with abdominal pain suggestive of acute pancreatitis. A 3-minute point-of-care UT test (Actim Pancreatitis; Medix Biochemica, Kauniainen, Finland) was compared with final diagnosis of acute pancreatitis, which was based on suggestive clinical features, serum lipase and/or amylase levels and imaging.
  
  
  RESULTS
  Of 124 patients included in this study, 69 patients had final diagnosis of acute pancreatitis. The sensitivity and specificity of UT were, respectively, 73.9% (95% CI 61.9% to 83.8%) and 94.6% (95% CI 84.9% to 98.9%).
  
  
  CONCLUSIONS
  The point-of-care UT test for acute pancreatitis had good sensitivity and specificity, and can be used reliably at the bedside to make a positive diagnosis.
authors.affiliation: P D Hinduja National Hospital and MRC, Mahim, Mumbai 400016.
authors.forename: Philip
authors.initials: P
authors.lastname: Abraham
mesh_terms: D000006:Abdomen, Acute / Q000209:etiology; D000208:Acute Disease; D000681:Amylases / Q000097:blood; D006801:Humans; D007194:India; D008049:Lipase / Q000097:blood; D010195:Pancreatitis / Q000175:diagnosis* / Q000652:urine*; D010361:Patients / Q000706:statistics & numerical data; D019095:Point-of-Care Systems; D011446:Prospective Studies; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014357:Trypsin / Q000652:urine*; D014362:Trypsinogen / Q000652:urine*
chemical_list: D014362:Trypsinogen; D008049:Lipase; D000681:Amylases; D014357:Trypsin