title: Pseudomonas aeruginosa bacteraemia in an adult with cystic fibrosis and acute appendicitis.
abstract: Despite their high bacterial load, bacteraemia is rare in patients with cystic fibrosis (CF). We report an adult with CF who developed Pseudomonas aeruginosa bacteraemia during an episode of acute appendicitis. The Pseudomonas aeruginosa isolated from the blood culture was confirmed by molecular typing to be the same transmissible strain responsible for the patient's chronic pulmonary infection. We hypothesise that this patient's bacteraemia was caused by Pseudomonas aerunginosa in swallowed sputum, crossing the inflamed appendiceal wall and entering the blood stream.
authors.affiliation: Manchester Adult Cystic Fibrosis Centre, University Hospital of South Manchester, Southmoor Road, Manchester, M23 9LT, UK.
authors.forename: Francis J
authors.initials: FJ
authors.lastname: Gilchrist
authors.forename: Catherine J
authors.initials: CJ
authors.lastname: Doherty
authors.forename: John R
authors.initials: JR
authors.lastname: Govan
authors.forename: A Kevin
authors.initials: AK
authors.lastname: Webb
authors.forename: Andrew M
authors.initials: AM
authors.lastname: Jones
mesh_terms: D000328:Adult; D001064:Appendicitis / Q000382:microbiology*; D016470:Bacteremia / Q000382:microbiology*; D003550:Cystic Fibrosis / Q000150:complications*; D005260:Female; D006801:Humans; D011552:Pseudomonas Infections / Q000150:complications*; D011550:Pseudomonas aeruginosa