title: Metformin-induced cholangiohepatitis.
abstract: Drug-induced cholangiohepatitis accounts for 20-50% of non-viral chronic hepatitis cases. Metformin is the most commonly prescribed oral anti-diabetic drug from the biguanide class used in treatment of overweight and obese type 2 diabetes mellitus patients. Metformin-induced cholangiohepatitis with marked elevations in serum liver transaminases and intrahepatic cholestasis has been infrequently reported. Here, we report a case of acute cholangiohepatitis after initiation of metformin treatment.
authors.affiliation: Case Western Reserve University @ MetroHealth Medical Center, Hospital Medicine, 2500 MetroHealth Dr, Cleveland, Ohio, 44138, USA.
authors.forename: Raja Shekhar Reddy Sappati
authors.initials: RS
authors.lastname: Biyyani
authors.forename: Smitha
authors.initials: S
authors.lastname: Battula
authors.forename: Christopher A
authors.initials: CA
authors.lastname: Erhardt
authors.forename: Khalil
authors.initials: K
authors.lastname: Korkor