title: [Primary cerebral lymphomatoid granulomatosis in a HIV-positive patient. Case report].
abstract: We report a 34-years-old male, with a history of hepatitis B and human immunodeficiency virus (HIV) infection that was admitted to the hospital with malaise, weight loss, frontal behavior and chest pain. Imaging studies showed two frontal cortical/subcortical nodules. A stereotactic cerebral biopsy showed reactive gliosis and a prominent atypical angiocentric and angiodestructive lymphoid infiltrate containing large pleomorphic CD20 and EBV-positive cells consistent with Lymphomatoid granulomatosis. Other studies were negative. The patient was lost from follow up.
authors.affiliation: Departamento de Anatomía Patológica, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
authors.forename: Kurt A
authors.initials: KA
authors.lastname: Schalper
authors.forename: José R
authors.initials: JR
authors.lastname: Valbuena
mesh_terms: D000328:Adult; D001706:Biopsy; D001921:Brain / Q000473:pathology*; D001932:Brain Neoplasms / Q000473:pathology*; D006679:HIV Seropositivity / Q000150:complications*; D006801:Humans; D016483:Lymphoma, AIDS-Related / Q000473:pathology*; D008230:Lymphomatoid Granulomatosis / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D008297:Male; D011379:Prognosis