title: Fatal bronchiolitis obliterans complicating Stevens-Johnson syndrome following treatment with nimesulide: a case report.
abstract: Nimesulide is a frequently used non-steroidal anti-inflammatory drug with analgesic and antipyretic effects in children. In view of fatal adverse drug reactions, however, its safety has been questioned. A 5-year-old boy developed Stevens-Johnson syndrome following use of nimesulide which was later complicated by rapidly progressive fatal bronchiolitis obliterans.
authors.affiliation: Department of Pediatrics, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
authors.forename: S
authors.initials: S
authors.lastname: Dogra
authors.forename: D
authors.initials: D
authors.lastname: Suri
authors.forename: A G
authors.initials: AG
authors.lastname: Saini
authors.forename: A
authors.initials: A
authors.lastname: Rawat
authors.forename: K S
authors.initials: KS
authors.lastname: Sodhi
mesh_terms: D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects*; D001989:Bronchiolitis Obliterans / Q000175:diagnosis* / Q000473:pathology*; D002675:Child, Preschool; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D013902:Radiography, Thoracic; D013262:Stevens-Johnson Syndrome / Q000139:chemically induced* / Q000150:complications*; D013449:Sulfonamides / Q000009:adverse effects*; D014057:Tomography, X-Ray Computed
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D013449:Sulfonamides; C012655:nimesulide