title: Severe compensatory hyperhidrosis following thoracic sympathectomy successfully treated with low doses of botulinum toxin A.
abstract: Compensatory hyperhidrosis is an adverse effect of thoracic sympathectomy that can be debilitating, which is why an efficient treatment is demanded. Botulinum toxin is an emerging treatment, not well known yet. We report two cases of compensatory hyperhidrosis following thoracic sympathectomy which were both treated with low doses of botulinum toxin A. The patients, a male and a female, noted a high level of satisfaction with the abolishment of sweating that was maintained up to 10 months. We consider that low doses of botulinum toxin A is a well tolerated, safe and effective treatment for compensatory hyperhidrosis and should be offered as an alternative treatment.
authors.affiliation: Experimental Surgery Unit, Hospital Dr. Negrín, Las Palmas de Gran Canaria, Spain. norbesr@terra.es
authors.forename: Norberto
authors.initials: N
authors.lastname: Santana-Rodríguez
authors.forename: Bernardino
authors.initials: B
authors.lastname: Clavo
authors.forename: Joaquín
authors.initials: J
authors.lastname: Calatayud-Gastardi
authors.forename: José Manuel
authors.initials: JM
authors.lastname: García-Castellano
authors.forename: Miguel A
authors.initials: MA
authors.lastname: Ponce-González
authors.forename: Vicente
authors.initials: V
authors.lastname: Olmo-Quintana
authors.forename: Pedro
authors.initials: P
authors.lastname: Llontop
authors.forename: Alejandro
authors.initials: A
authors.lastname: Alvarez-Prats
authors.forename: Nagib Atallah
authors.initials: NA
authors.lastname: Yordi
authors.forename: José Antonio
authors.initials: JA
authors.lastname: Ruíz-Caballero
mesh_terms: D000328:Adult; D019274:Botulinum Toxins, Type A / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D006945:Hyperhidrosis / Q000188:drug therapy* / Q000209:etiology* / Q000601:surgery; D007271:Injections, Intradermal; D008297:Male; D013562:Sympathectomy / Q000009:adverse effects*; D016896:Treatment Outcome
chemical_list: D019274:Botulinum Toxins, Type A