title: The association of current hormonal contraceptive use with type-specific HPV detection.
abstract: BACKGROUND
  Increased duration of hormonal contraceptive (HC) use may be positively associated with the risk of invasive cervical cancer.
  
  
  METHODS
  This is a secondary analysis from the HPV Sentinel Surveillance Study. The authors examined the association between type-specific human papillomavirus (HPV) detection and current HC use among 7718 women attending 26 sexually transmitted disease, family planning and primary care clinics in the USA.
  
  
  RESULTS
  There was an association between HC use and HPV-16 detection (adjusted prevalence rate ratio 1.34 (95% CI 1.05 to 1.71) for oral contraceptive users and 1.41 (1.01 to 2.04) for depot-medroxyprogesterone acetate users); there was no association between HC use and detection of other HPV types or any HPV overall.
  
  
  CONCLUSIONS
  Longitudinal studies are needed to better define this type-specific association and its clinical significance.
authors.affiliation: JHUBMC, ID Division, 4940 Eastern Ave, B3N Suite 352, Baltimore, MD 21224, USA. kghanem@jhmi.edu
authors.forename: Khalil G
authors.initials: KG
authors.lastname: Ghanem
authors.forename: S Deblina
authors.initials: SD
authors.lastname: Datta
authors.forename: Elizabeth R
authors.initials: ER
authors.lastname: Unger
authors.forename: Michael
authors.initials: M
authors.lastname: Hagensee
authors.forename: Judith C
authors.initials: JC
authors.lastname: Shlay
authors.forename: Peter
authors.initials: P
authors.lastname: Kerndt
authors.forename: Katherine
authors.initials: K
authors.lastname: Hsu
authors.forename: Laura A
authors.initials: LA
authors.lastname: Koutsky
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D003075:Coitus; D003271:Contraceptive Agents, Female / Q000009:adverse effects*; D003430:Cross-Sectional Studies; D005260:Female; D052162:Human papillomavirus 16; D006801:Humans; D017258:Medroxyprogesterone Acetate / Q000009:adverse effects*; D008875:Middle Aged; D030361:Papillomavirus Infections / Q000139:chemically induced*; D012307:Risk Factors; D018571:Sentinel Surveillance; D012747:Sexual Partners; D002578:Uterine Cervical Dysplasia / Q000821:virology; D055815:Young Adult
chemical_list: D003271:Contraceptive Agents, Female; D017258:Medroxyprogesterone Acetate