title: Synthesis of withanolide A, biological evaluation of its neuritogenic properties, and studies on secretase inhibition.
authors.affiliation: Department of Chemistry, University of Basel, St. Johanns-Ring 19, 4056 Basel, Switzerland.
authors.forename: Chandan Kumar
authors.initials: CK
authors.lastname: Jana
authors.forename: Johannes
authors.initials: J
authors.lastname: Hoecker
authors.forename: Tom M
authors.initials: TM
authors.lastname: Woods
authors.forename: Henning J
authors.initials: HJ
authors.lastname: Jessen
authors.forename: Markus
authors.initials: M
authors.lastname: Neuburger
authors.forename: Karl
authors.initials: K
authors.lastname: Gademann
mesh_terms: D053829:Amyloid Precursor Protein Secretases / Q000037:antagonists & inhibitors* / Q000378:metabolism; D002454:Cell Differentiation / Q000187:drug effects; D045744:Cell Line, Tumor; D018360:Crystallography, X-Ray; D006801:Humans; D008968:Molecular Conformation; D016501:Neurites / Q000187:drug effects / Q000502:physiology; D026082:Singlet Oxygen / Q000737:chemistry; D013237:Stereoisomerism; D032341:Withania / Q000737:chemistry; D054358:Withanolides / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology
chemical_list: C433551:3-rhamnopyranosyl(1-4)-glucopyranosyl-12-diacetoxy-20-hydroxywitha-5,24-dienolide; D054358:Withanolides; D026082:Singlet Oxygen; D053829:Amyloid Precursor Protein Secretases