title: Oral rehabilitation with implant-based prostheses of two adult patients treated for childhood rhabdomyosarcoma.
abstract: BACKGROUND
  Rhabdomyosarcoma is the most common malignant tumor in the nasal and paranasal sinus area at childhood. Multimodal treatment for this disorder has severe side effects due to normal tissue damage. As a result of this treatment, facial growth retardation and oral abnormalities such as malformation of teeth and microstomia can cause esthetic and functional problems.
  
  
  METHODS
  Two cases are presented of patients with severe midfacial hypoplasia and reduced oral function as a result of treatment of rhabdomyosarcoma of the nasopharyngeal and nasal-tonsil region. With a combined surgical (osteotomy, distraction osteogenesis, implants) and prosthetic (implant-based overdenture) treatment, esthetics and function were improved.
authors.affiliation: Department of Oral and Maxillofacial Surgery and Maxillofacial Prosthetics, University Medical Center Groningen, University of Groningen, P.O. Box 30.001-BB70, 9700 RB, Groningen, The Netherlands. a.korfage@kchir.umcg.nl
authors.forename: Anke
authors.initials: A
authors.lastname: Korfage
authors.forename: Kees
authors.initials: K
authors.lastname: Stellingsma
authors.forename: Johan
authors.initials: J
authors.lastname: Jansma
authors.forename: Arjan
authors.initials: A
authors.lastname: Vissink
authors.forename: Gerry M
authors.initials: GM
authors.lastname: Raghoebar
mesh_terms: D000328:Adult; D019094:Dental Prosthesis, Implant-Supported; D005153:Facial Neoplasms / Q000534:rehabilitation* / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D019767:Maxillofacial Abnormalities / Q000209:etiology / Q000534:rehabilitation / Q000601:surgery; D008865:Microstomia / Q000209:etiology / Q000534:rehabilitation / Q000601:surgery; D019857:Osteogenesis, Distraction / Q000379:methods; D010027:Osteotomy / Q000379:methods; D012208:Rhabdomyosarcoma / Q000534:rehabilitation* / Q000601:surgery; D016896:Treatment Outcome; D055815:Young Adult