title: Directed heterodimerization: stereocontrolled assembly via solvent-caged unsymmetrical diazene fragmentation.
abstract: A general strategy for the directed and stereocontrolled assembly of carbon-carbon linked heterodimeric hexahydropyrroloindoles is described. The stepwise union of complex amines in the form of mixed diazenes followed by photoexpulsion of dinitrogen in a solvent cage provides completely guided assembly at challenging C(sp(3))-C(sp(3)) and C(sp(3))-C(sp(2)) connections.
authors.affiliation: Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA. movassag@mit.edu
authors.forename: Mohammad
authors.initials: M
authors.lastname: Movassaghi
authors.forename: Omar K
authors.initials: OK
authors.lastname: Ahmad
authors.forename: Stephen P
authors.initials: SP
authors.lastname: Lathrop
mesh_terms: D019281:Dimerization; D007094:Imides / Q000737:chemistry*; D007211:Indoles; D012997:Solvents; D013237:Stereoisomerism
chemical_list: D007094:Imides; D007211:Indoles; D012997:Solvents; C038867:diazene