title: [Comparative study of mucosa irritation of crude and processed Radix Phytolaccae].
abstract: OBJECTIVE
  To study the changes of mucosa irritation of crude and processed Radix Phytolaccae.
  
  
  METHODS
  Gastrointestinal experiments on rats and mice and the rabbits' eyes irritation experiments were applied to investigate the changes of mucosa irritation of crude and processed Radix Phytolaccae.
  
  
  RESULTS
  The mucosa irritation of processed Radix Phytolaccae decreased obviously compared to crude one.
  
  
  CONCLUSIONS
  After being processed with vinegar, the mucosa irritation on Radix Phytolaccae decreased obviously.
authors.affiliation: Pharmacology College of Nanjing University of Chinese Medicine, Nanjing 210029. chenliner198506@163.com
authors.forename: Lin
authors.initials: L
authors.lastname: Chen
authors.forename: Hao
authors.initials: H
authors.lastname: Wu
authors.forename: Mei
authors.initials: M
authors.lastname: Wang
authors.forename: Runjun
authors.initials: R
authors.lastname: Shi
mesh_terms: D019342:Acetic Acid / Q000737:chemistry; D000818:Animals; D015232:Dinoprostone / Q000378:metabolism; D004339:Drug Compounding; D004365:Drugs, Chinese Herbal / Q000009:adverse effects* / Q000737:chemistry*; D005123:Eye / Q000187:drug effects; D005753:Gastric Mucosa / Q000187:drug effects* / Q000378:metabolism; D008297:Male; D051379:Mice; D029603:Phytolacca / Q000737:chemistry*; D018517:Plant Roots / Q000737:chemistry*; D051381:Rats
chemical_list: D004365:Drugs, Chinese Herbal; D015232:Dinoprostone; D019342:Acetic Acid