title: Mandibular osteomyelitis associated with paroxysmal nocturnal hemoglobinuria.
abstract: A case of osteomyelitis in a 71-year-old woman with paroxysmal nocturnal hemoglobinuria (PNH) is reported. Osteomyelitis of the jaw is a well known condition of the oral and maxillofacial region that may cause severe morbidity. It is well documented that vaso-occlusive crises in sickle cell anaemia, a hemolytic blood disorder, can make the jaw bone susceptible to osteomyelitis. The authors report a case proposing an association between PNH and osteomyelitis of the mandible.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Central Hospital, Västerås, Sweden.
authors.forename: M
authors.initials: M
authors.lastname: Kharazmi
authors.forename: K
authors.initials: K
authors.lastname: Carlson
authors.forename: L
authors.initials: L
authors.lastname: Björnstad
authors.forename: A
authors.initials: A
authors.lastname: Petersson
authors.forename: G
authors.initials: G
authors.lastname: Warfvinge
mesh_terms: D000368:Aged; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D002908:Chronic Disease; D005260:Female; D005500:Follow-Up Studies; D005938:Glucocorticoids / Q000627:therapeutic use; D006457:Hemoglobinuria, Paroxysmal / Q000150:complications*; D006801:Humans; D008336:Mandibular Diseases / Q000209:etiology*; D010019:Osteomyelitis / Q000209:etiology*; D010026:Osteosclerosis / Q000209:etiology; D011239:Prednisolone / Q000627:therapeutic use; D011862:Radiography, Panoramic
chemical_list: D000893:Anti-Inflammatory Agents; D005938:Glucocorticoids; D011239:Prednisolone