title: 1,3-dipolar cycloadditions from tricyclic hemiaminals. Synthesis of the quinocarcin core through catalyst-free generation of azomethine ylides.
abstract: The generation of azomethine ylides from the readily accessible hemiaminals 3 and 8 or from iminium salt 10 was studied. Compounds 8 gave anti- and syn-cycloadducts containing the quinocarcin core through a catalyst-free dehydration process.
authors.affiliation: Departamento de Química Orgánica y Farmacéutica, Facultad de Farmacia, Universidad Complutense, Madrid, Spain.
authors.forename: Lena
authors.initials: L
authors.lastname: Huck
authors.forename: J Francisco
authors.initials: JF
authors.lastname: González
authors.forename: Elena
authors.initials: E
authors.lastname: de la Cuesta
authors.forename: J Carlos
authors.initials: JC
authors.lastname: Menéndez
authors.forename: Carmen
authors.initials: C
authors.lastname: Avendaño
mesh_terms: D000588:Amines / Q000737:chemistry*; D001391:Azo Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D003500:Cyclization; D007097:Imines / Q000737:chemistry; D007546:Isoquinolines / Q000138:chemical synthesis* / Q000737:chemistry; D013882:Thiosemicarbazones / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D000588:Amines; D001391:Azo Compounds; D007097:Imines; D007546:Isoquinolines; D013882:Thiosemicarbazones; C512188:azomethine; C038710:quinocarcin