title: Changing the odds. What do we learn from prevention studies targeted at people with a positive family history of type 2 diabetes?
abstract: People with a positive family history of type 2 diabetes (T2DM) are at high risk of developing diabetes. We set out to review the literature reporting on the development and/or evaluation of lifestyle interventions specifically aimed at prevention of T2DM in this group. Targeting people with a positive family history of T2DM seems so far an underutilized prevention strategy. They can and should be approached with the aim to raise risk awareness and promote healthy eating, weight loss and physical activity, thereby reducing their risk of developing diabetes.
authors.affiliation: Department of Medical Psychology, The EMGO Institute for Health and Care Research, VU University Medical Centre, Amsterdam, The Netherlands. w.heideman@vumc.nl
authors.forename: Wieke H
authors.initials: WH
authors.lastname: Heideman
authors.forename: Barend J C
authors.initials: BJ
authors.lastname: Middelkoop
authors.forename: Vera
authors.initials: V
authors.lastname: Nierkens
authors.forename: Karien
authors.initials: K
authors.lastname: Stronks
authors.forename: Arnoud P
authors.initials: AP
authors.lastname: Verhoeff
authors.forename: Suzanne C M
authors.initials: SC
authors.lastname: van Esch
authors.forename: Frank J
authors.initials: FJ
authors.lastname: Snoek
mesh_terms: D000328:Adult; D003924:Diabetes Mellitus, Type 2 / Q000209:etiology / Q000235:genetics / Q000517:prevention & control*; D004032:Diet; D019317:Evidence-Based Medicine; D015444:Exercise; D020022:Genetic Predisposition to Disease; D040941:Heredity; D006801:Humans; D008875:Middle Aged; D010375:Pedigree; D011322:Primary Prevention / Q000379:methods*; D012107:Research Design; D018570:Risk Assessment; D012307:Risk Factors; D040242:Risk Reduction Behavior; D016896:Treatment Outcome