title: [Timeline trends in surgery of bronchogenic carcinoma].
abstract: BACKGROUND
  The aim of our study was to determine how patient preoperative status and outcomes of resection have changed over last 12 years.
  
  
  METHODS
  This retrospective study of prospective database included 1412 patients operated from January 1,1998 through December 31,2009. Patient characteristics and outcomes were compared for two time periods (1998-2003 and 2004-2009).
  
  
  RESULTS
  We performed 985 lobectomies with 30-days mortality 1.8% and 300 pneumonectomies with 30-days mortality 5.7%. Median of survival of all 1412 patients was 4.3 year and 5-year survival was 45%. The percentage of female patients, lobectomies and adenocarcinoma increased over time, as well as age of our patients. Outcome improved over time, with significant decrease in 30-days mortality after pneumonectomy (8.2% vs. 2.3%, p = 0.029). The overall 3-year survival improved in patients with III. stage (30 % vs. 40%, p = 0.012).
  
  
  CONCLUSIONS
  Our study identified time trends which are in-line with increased incidence of lung cancer among women and with improvement of preoperative evaluation, preoperative and postoperative care
authors.affiliation: III. chirurgická klinika 1. LF UK a FN Motol, Praha. stolz@seznam.cz
authors.forename: A
authors.initials: A
authors.lastname: Stolz
authors.forename: J
authors.initials: J
authors.lastname: Simonek
authors.forename: T
authors.initials: T
authors.lastname: Harustiak
authors.forename: J
authors.initials: J
authors.lastname: Schützner
authors.forename: P
authors.initials: P
authors.lastname: Pafko
authors.forename: R
authors.initials: R
authors.lastname: Lischke
mesh_terms: D002283:Carcinoma, Bronchogenic / Q000401:mortality / Q000601:surgery*; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000401:mortality / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D011013:Pneumonectomy / Q000009:adverse effects; D011183:Postoperative Complications; D015996:Survival Rate