title: [Complications after endothelial keratoplasty: three years of experience].
abstract: OBJECTIVE
  To study the complications after Descemet's stripping automated endothelial keratoplasty (DSAEK).
  
  
  METHODS
  Retrospective study of 75 eyes in 67 patients with Fuchs' endothelial dystrophy or bullous keratopathy operated on in the Instituto de Oftalmología La Arruzafa from March, 2007 until March, 2010. Phacoemulsification and IOL implantation was involved in 30 cases. All surgical and post-surgical complications, as well as the endothelial cell density were recorded.
  
  
  RESULTS
  Graft detachment was the most common complication: 17 cases (22.5%); 16 of them resolved with reintroduction of air in the anterior chamber. The rate of detachment in cases without capsular support (8 eyes) increased up to 50%. Five cases had primary graft failure and, in 2 cases, a medium term failure was observed. Only one case of endothelial rejection was observed (1.3%). Five eyes (6.5%) developed a pupillary block, but of them were solved with the aspiration of the air. In one eye (1.3%), a posterior capsule rupture was observed during the phacoemulsification. This case ended with a retinal detachment. The endothelial cell loss was 42.75%.
  
  
  CONCLUSIONS
  DSAEK is an effective surgical technique to resolve the corneal oedema due to endothelial failure; however, complications are not uncommon. Graft detachment is the most common complication, but is usually resolved with re-bubbling. There is an evident learning curve and the surgical trauma to the endothelium is the most important factor that influences the endothelial cell loss.
authors.affiliation: Instituto de Oftalmología La Arruzafa, Grupo INNOVA, Córdoba, España. alvillarrubia@yahoo.com
authors.forename: A
authors.initials: A
authors.lastname: Villarrubia
authors.forename: E
authors.initials: E
authors.lastname: Palacín
authors.forename: C
authors.initials: C
authors.lastname: Aránguez
authors.forename: J
authors.initials: J
authors.lastname: Solana
authors.forename: C R
authors.initials: CR
authors.lastname: García-Alonso
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000867:Anterior Chamber; D001768:Blister / Q000601:surgery; D003316:Corneal Diseases / Q000601:surgery; D057111:Descemet Stripping Endothelial Keratoplasty / Q000009:adverse effects; D004728:Endothelium, Corneal / Q000601:surgery; D005260:Female; D005642:Fuchs' Endothelial Dystrophy / Q000601:surgery; D006801:Humans; D019654:Lens Implantation, Intraocular; D007906:Lens Subluxation / Q000453:epidemiology* / Q000209:etiology; D008297:Male; D008875:Middle Aged; D018918:Phacoemulsification; D011183:Postoperative Complications / Q000453:epidemiology* / Q000209:etiology; D055031:Primary Graft Dysfunction / Q000453:epidemiology / Q000209:etiology; D012030:Refractive Errors / Q000453:epidemiology / Q000209:etiology; D012086:Reoperation; D012189:Retrospective Studies; D016896:Treatment Outcome; D055815:Young Adult