title: Management of children with thrombocytopenia-absent radius syndrome: an institutional experience.
abstract: OBJECTIVE
  Thrombocytopenia-absent radius (TAR) syndrome is characterised by bilateral absence of the radii in the presence of both thumbs and hypomegakaryocytic thrombocytopenia. We report our experience of three patients affected by TAR syndrome presenting with different clinical manifestations focusing on the management of these patients.
  
  
  RESULTS
  We propose the use of long-term central venous catheters to reduce discomfort because of repeated vein punctures in search for a venous access, rendered difficult by upper limbs abnormalities.
  
  
  CONCLUSIONS
  It is important to improve the quality of life of affected patients.
authors.affiliation: Division of Paediatric Oncology, Department of Surgery, Catholic University of Rome, Rome, Italy. p.coccia@fastwebnet.it
authors.forename: Paola
authors.initials: P
authors.lastname: Coccia
authors.forename: Antonio
authors.initials: A
authors.lastname: Ruggiero
authors.forename: Stefano
authors.initials: S
authors.lastname: Mastrangelo
authors.forename: Giorgio
authors.initials: G
authors.lastname: Attinà
authors.forename: Maria
authors.initials: M
authors.lastname: Scalzone
authors.forename: Mauro
authors.initials: M
authors.lastname: Pittiruti
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Zampino
authors.forename: Palma
authors.initials: P
authors.lastname: Maurizi
authors.forename: Riccardo
authors.initials: R
authors.lastname: Riccardi
mesh_terms: D000015:Abnormalities, Multiple; D002405:Catheterization, Central Venous / Q000379:methods*; D000080984:Congenital Bone Marrow Failure Syndromes; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D011884:Radius / Q000002:abnormalities*; D013921:Thrombocytopenia / Q000628:therapy*; D013933:Thumb / Q000002:abnormalities; D038062:Upper Extremity Deformities, Congenital / Q000628:therapy*