title: Highly enantioselective Michael addition of 2-oxindoles to vinyl selenone in RTILs catalyzed by a Cinchona alkaloid-based thiourea.
abstract: A highly enantioselective Michael addition of 2-oxindoles (1) to vinyl selenone (2) in RTILs catalyzed by a Cinchona alkaloid-based thiourea has been developed in high yields (80-91%) with excellent enantioselectivities (up to 95% ee).
authors.affiliation: Beijing National Laboratory for Molecular Sciences (BNLMS), Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China.
authors.forename: Tao
authors.initials: T
authors.lastname: Zhang
authors.forename: Liang
authors.initials: L
authors.lastname: Cheng
authors.forename: Shahid
authors.initials: S
authors.lastname: Hameed
authors.forename: Li
authors.initials: L
authors.lastname: Liu
authors.forename: Dong
authors.initials: D
authors.lastname: Wang
authors.forename: Yong-Jun
authors.initials: YJ
authors.lastname: Chen
mesh_terms: D002384:Catalysis; D002930:Cinchona Alkaloids / Q000737:chemistry; D007211:Indoles / Q000737:chemistry*; D052578:Ionic Liquids / Q000737:chemistry*; D000078183:Oxindoles; D012643:Selenium / Q000737:chemistry*; D013237:Stereoisomerism; D013696:Temperature; D013890:Thiourea / Q000737:chemistry*; D014753:Vinyl Compounds / Q000737:chemistry
chemical_list: D002930:Cinchona Alkaloids; D007211:Indoles; D052578:Ionic Liquids; D000078183:Oxindoles; D014753:Vinyl Compounds; C022960:2-oxindole; D013890:Thiourea; D012643:Selenium