title: Bilateral femoral insufficiency fractures likely related to long-term alendronate therapy.
abstract: Osteoporosis-related fractures are a major public health problem and one in two women and one in four men are affected with osteoporosis-related fractures. Alendronate (Fosamax) is one of the first bisphosphonates used to treat osteoporosis effectively. Recently, however, there is a concern regarding long bone insufficiency fractures related to long-term alendronate therapy. We report a case of bilateral femoral insufficiency fractures likely related to long-term alendronate therapy, the classic symptoms, signs, and treatment of these fractures.
authors.affiliation: Department of Orthopedics, University of Calgary, 711B, 3607-49 ST NW, Calgary, Alberta, Canada T3A 2H3.
authors.forename: Ravindra
authors.initials: R
authors.lastname: Gudena
authors.forename: Jason
authors.initials: J
authors.lastname: Werle
authors.forename: Kelly
authors.initials: K
authors.lastname: Johnston