title: Bilateral posterior subcapsular cataracts associated with long-term intranasal steroid use.
abstract: The use of systemic steroids has been established as a risk factor for the development of posterior subcapsular cataracts. In recent decades, the use of nasal topical steroids has increased in an effort to decrease systemic side effects. Current evidence of an association between nasal steroid use and cataract formation is contradictory. We present a case of rapid-onset bilateral posterior subcapsular cataracts in a young healthy patient with a history of long-term nasal steroid use.
authors.affiliation: Department of Ophthalmology, Stanford University School of Medicine, Palo Alto, California 94303, USA.
authors.forename: Anthony
authors.initials: A
authors.lastname: Liu
authors.forename: Edward E
authors.initials: EE
authors.lastname: Manche
mesh_terms: D057128:Aberrometry; D000281:Administration, Intranasal; D000328:Adult; D000730:Androstadienes / Q000008:administration & dosage / Q000009:adverse effects*; D002386:Cataract / Q000139:chemically induced* / Q000175:diagnosis; D000068298:Fluticasone; D005938:Glucocorticoids / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D008297:Male; D057852:Posterior Capsule of the Lens / Q000187:drug effects* / Q000473:pathology; D006255:Rhinitis, Allergic, Seasonal / Q000188:drug therapy
chemical_list: D000730:Androstadienes; D005938:Glucocorticoids; D000068298:Fluticasone