title: Correlation between crossed cerebellar diaschisis and clinical neurological scales.
abstract: BACKGROUND
  A common consequence of unilateral stroke is crossed cerebellar diaschisis (CCD), a decrease in regional blood flow (CBF) and metabolism (CMRglu) in the cerebellar hemisphere contralateral to the affected cerebral hemisphere. Former studies indicated a post-stroke time-dependent relationship between the degree of CCD and the clinical status of acute and sub-acute stroke patients, but no study has been performed in post-stroke patients.
  
  
  OBJECTIVE
  The objective of this investigation was to evaluate the quantitative correlation between the degree of CCD and the values of clinical stroke scales in post-stroke patients.
  
  
  METHODS
  We measured with positron emission tomography (PET) regional CBF and CMRglu values in the affected cortical regions and the contralateral cerebellum in ten ischaemic post-stroke patients. Based on these quantitative parameters, the degree of diaschisis (DoD) was calculated, and the DoD values were correlated with three clinical stroke scales [Barthel Index, Orgogozo Scale and Scandinavian Neurological Scale (SNS)].
  
  
  RESULTS
  There were significant linear correlations between all clinical stroke scales and the CCD values (Barthel Index and Orgogozo Scale: P < 0.001, for both CBF and CMRglu; SNS: P = 0.007 and P = 0.044; CBF and CMRglu, respectively).
  
  
  CONCLUSIONS
  The findings indicate that DoD can be used as a quantitative indicator of the functional impairments following stroke, i.e. it can serve as a potential surrogate of the severity of the damage.
authors.affiliation: Department of Neurology, State Health Center, Budapest, Hungary.
authors.forename: G
authors.initials: G
authors.lastname: Szilágyi
authors.forename: A
authors.initials: A
authors.lastname: Vas
authors.forename: L
authors.initials: L
authors.lastname: Kerényi
authors.forename: Z
authors.initials: Z
authors.lastname: Nagy
authors.forename: L
authors.initials: L
authors.lastname: Csiba
authors.forename: B
authors.initials: B
authors.lastname: Gulyás
mesh_terms: D000368:Aged; D002545:Brain Ischemia / Q000000981:diagnostic imaging / Q000209:etiology / Q000378:metabolism / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D049268:Positron-Emission Tomography; D012039:Regional Blood Flow; D012042:Registries; D012720:Severity of Illness Index; D020521:Stroke / Q000150:complications / Q000000981:diagnostic imaging / Q000378:metabolism / Q000503:physiopathology*