title: Reproductive characteristics of a captive colony of big-eared climbing rats (Ototylomys phyllotis).
abstract: The authors analyzed the breeding characteristics of a colony of Ototylomys phyllotis (big-eared climbing rat) from Campeche, México, that was bred in captivity for 6 y. The big-eared climbing rat is a reservoir of Leishmania (Leishmania) mexicana, a causal agent of localized cutaneous leishmaniasis on the Yucatán Peninsula. The colony had been established to facilitate studies analyzing the effectiveness of O. phyllotis as an experimental model for L. (L.) mexicana. The authors describe the housing and husbandry of the colony, the procedures used for mating the animals and the behavior of the animals during mating. They report that the animals showed social behavior and could be bred successfully. Most breeding pairs successfully produced litters; some pairs produced more than one litter. The authors also report data for other parameters, such as the interval between pairing and birth or between births of consecutive litters, litter size, survival to weaning, the timing of sexual maturity and the effects of breeder age on breeding success.
authors.affiliation: Instituto de Ciencias Biomédicas, Departamento de Ciencias Veterinarias, Universidad Autónoma de Ciudad Juárez, Ciudad Juárez, Chihuahua, México.
authors.forename: Mateo F
authors.initials: MF
authors.lastname: Itzá-Ortiz
authors.forename: Nicole R
authors.initials: NR
authors.lastname: Van Wynsberghe
authors.forename: Erika I
authors.initials: EI
authors.lastname: Sosa-Bibiano
authors.forename: Fernando J
authors.initials: FJ
authors.lastname: Andrade-Narváez
mesh_terms: D000822:Animal Husbandry / Q000379:methods*; D000818:Animals; D004195:Disease Models, Animal; D004197:Disease Reservoirs / Q000469:parasitology / Q000662:veterinary*; D030762:Estrous Cycle / Q000502:physiology; D005260:Female; D007894:Leishmania mexicana / Q000302:isolation & purification / Q000502:physiology; D016773:Leishmaniasis, Cutaneous / Q000473:pathology / Q000662:veterinary*; D008297:Male; D012098:Reproduction / Q000502:physiology*; D012377:Rodentia / Q000469:parasitology / Q000502:physiology*