title: Severe neuropsychiatric presentation of Wilson's disease.
abstract: Wilson's disease (WD) is a relatively rare disease of copper metabolism. The diagnosis is often missed initially. The presentation is usually neurologic or hepatic, seen in 40% of patients. Psychiatric presentation of WD is reported in only 15% of patients. We present a 32-year-old patient with severe psychiatric manifestations. On examination, he had mild rest and postural tremors and a KF ring was seen. Serum ceruloplasmin was low and 24-hour urinary copper was elevated. The patient responded to penicillamine, lorazepam and quetiapine, and is being followed up.
authors.affiliation: Department of Neurology, T. N. M. C. and B. Y. L. Nair Charitable Hospital, Mumbai Central, Mumbai, Maharashtra, India.
authors.forename: Rahul T
authors.initials: RT
authors.lastname: Chakor
authors.forename: N S
authors.initials: NS
authors.lastname: Santhosh