title: Adrenal adenomatoid tumor in a patient with human immunodeficiency virus.
abstract: We present the clinical course of a patient with human immunodeficiency virus and an adrenal adenomatoid tumor (AAT). We describe the clinical course and laboratory, radiographic, and microscopic findings of a patient with human immunodeficiency virus (HIV) and an adenomatoid tumor of the right adrenal gland. A review of the literature was also done via electronic searches through PubMed for articles from 1965 to 2008 that contained the following search terms, adenomatoid tumor limited to the English language only. A 22 year-old African-American male with HIV was incidentally found to have a hypermetabolic right adrenal mass. The patient underwent laparoscopic adrenalectomy and the mass had morphological and immunohistochemical features that were consistent with an AAT. A review of the medical literature reveals that almost all cases of AAT were in male patients (96%) with a mean age of 41±11 years (range=22-64) with no significant difference in laterality (right side=46%, left side=50%, unknown=4%). AAT have an average size of 4.2±3.5 cm (range=0.5-14.3 cm). Pre-operative imaging studies do not appear to be able to reliably distinguish AAT from other types of adrenocortical tumors. For reasons that require further research, AAT typically occur in male patients and may be associated with immunosuppression. AAT can be safely removed laparoscopically with no evidence of long-term recurrence even with tumor extension beyond the adrenal capsule.
authors.affiliation: Department of Surgery, The Massachusetts General Hospital, Harvard Medical School, Boston, MA;
authors.forename: Roy
authors.initials: R
authors.lastname: Phitayakorn
authors.forename: Gregory
authors.initials: G
authors.lastname: Maclennan
authors.forename: Peter
authors.initials: P
authors.lastname: Sadow
authors.forename: Scott
authors.initials: S
authors.lastname: Wilhelm