title: Preparation and antioxidant capacity of element selenium nanoparticles sol-gel compounds.
abstract: This paper reported the preparation and antioxidant capacities of element selenium nanoparticles (nanoSe(0))-ascorbic acid (Vc) sol and nanSe(0)/Vc/selenocystine (SeCys) sol-gel compounds. NanoSe(0)-Vc sol was prepared by reduction of selenious dioxide (SeO2) with Vc. In the nanoSe(0)-Vc sol, highly concentrated Vc was also used as a modifier to modulate the diameter of Se(0) nanoparticles in the liquid phase. Then excellent nanoSe(0) sol-gel compounds were obtained by adding SeCys into the nanoSe(0)-Vc sol. The structure of the nanoSe(0)/Vc/SeCys sol-gel compounds was defined, which was constructed via C-Se, Se-H and O=C-Se valences and by interaction between SeCys and Vc via peptide bonds, esterification and dehydration. The antioxidant capacities of the nanoSe(0)-Vc sol and the nanoSe(0)Vc/SeCys sol-gel compounds were estimated by oxygen radical absorption capacity (ORAC) assay. The nanoSe(0)/Vc/SeCys sol-gel compounds possessed a strong antioxidant capacity due to forming the perfect three-dimensional (3D) frameworks structure. The results suggested that the nanoSe(0)-Vc sol and the nanoSe(0)Vc/SeCys sol-gel compounds might be potential medicine, especially antioxidant.
authors.affiliation: College of Life Science and Technology of Jinan University, Guangzhou 510632, People's Republics of China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Bai
authors.forename: Biyin
authors.initials: B
authors.lastname: Qin
authors.forename: Yanhui
authors.initials: Y
authors.lastname: Zhou
authors.forename: Yudong
authors.initials: Y
authors.lastname: Wang
authors.forename: Zi
authors.initials: Z
authors.lastname: Wang
authors.forename: Wenjie
authors.initials: W
authors.lastname: Zheng
mesh_terms: D000042:Absorption; D000975:Antioxidants / Q000737:chemistry*; D019540:Area Under Curve; D001205:Ascorbic Acid / Q000737:chemistry; D019793:Fluorescein; D008854:Microscopy, Electron; D053758:Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D044367:Phase Transition; D012643:Selenium / Q000737:chemistry*; D017279:Selenocysteine / Q000737:chemistry; D017550:Spectroscopy, Fourier Transform Infrared
chemical_list: D000975:Antioxidants; D017279:Selenocysteine; D012643:Selenium; D001205:Ascorbic Acid; D019793:Fluorescein