title: [Application of different nutrition therapies in pregnancy with abnormal glucose metabolism].
abstract: OBJECTIVE
  To explore the effect of different nutrition therapies on abnormal glucose metabolism during pregnancy and pregnancy outcomes.
  
  
  METHODS
  The 83 cases of pregnant women with abnormal glucose metabolism who came to nutrition clinic were randomly divided into two groups before 30 weeks pregnancy: 42 cases in traditional food exchange serving group (FES) and 41 cases in food exchange serving based on glycemic load group (FES + GL). Traditional food exchange serving and food exchange serving based on glycemic load were used as the different nutrition therapies for two groups respectively until the time of delivery. The influence of two nutrition therapies on the blood glucose and pregnancy outcomes were observed.
  
  
  RESULTS
  The daily food glucose load (GL) after nutrition therapy in the FES + GL group (145.9 ± 26.3) were significantly decreased than that of the FES group (179.9 ± 28.9, t = 5.602, P < 0.01). Fasting plasma glucose (FPG) and 2 h postprandial glucose (2 h PG) ((4.63 ± 0.97) and (6.15 ± 1.07) mmol/L, respectively) after nutrition therapy in the FES + GL group were significantly lower than that in pre-nutrition therapy ((4.96 ± 0.81) and (9.13 ± 1.61) mmol/L, t = 2.237, 11.202, respectively, all P values < 0.05). The 2 h PG in the FES + GL group ((6.15 ± 1.07) mmol/L) after nutrition therapy was significantly lower than that of the FES group ((6.86 ± 1.26) mmol/L, t = 2.760, P < 0.05). 19.51% (8/41) of the total incidence of complications in the FES + GL group was lower than that (11/42, 26.19%) in the FES group, but the difference was not significant (χ² = 0.524, P > 0.05).
  
  
  CONCLUSIONS
  FES based on GL was much easier to reduce blood glucose compared with FES. Two nutrition therapies can improve maternal and neonatal outcomes in pregnant women with abnormal glucose metabolism.
authors.affiliation: Department of Nutrition, Guangdong General Hospital, Guangdong Academy of Medical Science, Guangzhou 510080, China.
authors.forename: Wen-jun
authors.initials: WJ
authors.lastname: Ma
authors.forename: Ben-hua
authors.initials: BH
authors.lastname: Qi
authors.forename: Yan-jun
authors.initials: YJ
authors.lastname: Zhang
authors.forename: Zhi-hong
authors.initials: ZH
authors.lastname: Huang
authors.forename: Ben-xi
authors.initials: BX
authors.lastname: Xiao
authors.forename: Yuan-hong
authors.initials: YH
authors.lastname: Li
authors.forename: Wei
authors.initials: W
authors.lastname: Yu
authors.forename: Hui-lian
authors.initials: HL
authors.lastname: Zhu
mesh_terms: D000328:Adult; D001786:Blood Glucose / Q000378:metabolism; D016640:Diabetes, Gestational / Q000178:diet therapy* / Q000378:metabolism; D005260:Female; D044882:Glucose Metabolism Disorders / Q000178:diet therapy* / Q000378:metabolism; D006801:Humans; D018529:Nutritional Support / Q000379:methods*; D011247:Pregnancy
chemical_list: D001786:Blood Glucose