title: Studies based on the Danish Multiple Sclerosis Registry.
abstract: BACKGROUND
  This paper reviews the most important articles using data from the Danish Multiple Sclerosis Registry (DMSR) published in the past 25 years.
  
  
  RESULTS
  These articles include: descriptive epidemiological studies, indicating that the female incidence of multiple sclerosis (MS) in Denmark has increased considerably; follow-up studies on social events, showing that patients at a high rate lose their working ability and their spouses/partners; mortality studies, demonstrating a considerable excess mortality; cause-of-death studies; comorbidity studies; and, most importantly, historical prospective studies identifying some risk factors (e.g. infectious mononucleosis) and refuting others (head trauma and a number of occupational exposures e.g. nurses, utility workers, people exposed to solvents). The most important results are briefly presented.
  
  
  CONCLUSIONS
  The Danish MS register has proven to be a valuable tool for MS epidemiology and has provided knowledge that could not otherwise be achieved.
authors.affiliation: The Danish Multiple Sclerosis Registry, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark. nils.koch-henriksen@rh.regionh.dk
authors.forename: Nils
authors.initials: N
authors.lastname: Koch-Henriksen
authors.forename: Egon
authors.initials: E
authors.lastname: Stenager
authors.forename: Henrik
authors.initials: H
authors.lastname: Brønnum-Hansen
mesh_terms: D015331:Cohort Studies; D003718:Denmark / Q000453:epidemiology; D004781:Environmental Exposure / Q000009:adverse effects; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D008297:Male; D009103:Multiple Sclerosis / Q000150:complications / Q000453:epidemiology* / Q000401:mortality; D011379:Prognosis; D011446:Prospective Studies; D012042:Registries / Q000592:standards; D012307:Risk Factors