title: Epidemiological survey of Border disease virus among sheep from northern districts of Japan.
abstract: The first epidemiological survey of Border disease virus (BDV) was undertaken in small ruminants in Japan. Ovine sera, collected from the northern prefectures of Hokkaido, Aomori and Iwate, were examined for the presence of antibodies against BDV using the neutralization peroxidase-linked antibody test. Twenty-nine (17.6%) of one hundred and sixty-five samples were seropositive for BDV. Results were specific, excluding cross-reactions with bovine viral diarrhea virus (BVDV). Only one sample (0.6%) was positive for BVDV, and was negative for BDV. Despite serological evidence of virus circulation, there have been no clinical cases of border disease in sheep in Japan. Although no diagnostic measures were performed, the infection did not appear to be associated with a reduction in ewe fertility nor with lamb mortality.
authors.affiliation: Department of Veterinary Microbiology, School of Veterinary Medicine, Faculty of Agriculture, Iwate University, Morioka, Iwate 020–8550, Japan.
authors.forename: Massimo
authors.initials: M
authors.lastname: Giangaspero
authors.forename: Georgina
authors.initials: G
authors.lastname: Ibata
authors.forename: Giovanni
authors.initials: G
authors.lastname: Savini
authors.forename: Takeshi
authors.initials: T
authors.lastname: Osawa
authors.forename: Shingo
authors.initials: S
authors.lastname: Tatami
authors.forename: Eishu
authors.initials: E
authors.lastname: Takagi
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Moriya
authors.forename: Norimoto
authors.initials: N
authors.lastname: Okura
authors.forename: Atsushi
authors.initials: A
authors.lastname: Kimura
authors.forename: Ryô
authors.initials: R
authors.lastname: Harasawa
mesh_terms: D000818:Animals; D001882:Border Disease / Q000453:epidemiology*; D018083:Border disease virus / Q000302:isolation & purification*; D005260:Female; D007564:Japan / Q000453:epidemiology; D008297:Male; D016036:Seroepidemiologic Studies; D012756:Sheep