title: Changing trends in mortality of thyroid cancer in Belgrade population.
abstract: OBJECTIVE
  Thyroid cancer patients have favorable prognosis. The aim of this study was to analyze changing trends in mortality of thyroid cancer in Belgrade, during the period between 1987 and 2006.
  
  
  METHODS
  Mortality data were obtained from the Belgrade Office of Statistics. Mortality rates per 100,000 inhabitants were standardized according to the Segi's world population. Regression analysis was used to estimate the thyroid cancer mortality trend for the period 1987-2006.
  
  
  RESULTS
  The average percent of deaths due to thyroid cancer among all deaths was almost 2-fold higher in females (0.11%) than in males (0.6%), as well as among deaths due to all malignancies (females 0.54% and males 0.27%). During this 20-year period, the average standardized mortality rate was 1.5 times higher in females (0.74 per 100.000) than in males (0.51 per 100.000). In the observed period, the mortality rates for thyroid cancer were increased (+0.40%) in women and decreased (-0.42%) in men. In particular, in the 60-69 years age group in males, a significant trend for mortality decrease of 3.5%/year was detected.
  
  
  CONCLUSIONS
  Belgrade is classified in the regions with low risk of dying due to thyroid malignancies. The increasing trend of thyroid cancer mortality in females during the examined period calls for improvement of methods for early detection of disease and differential diagnosis of thyroid nodules, so that surgical treatment of thyroid cancer could be performed at a stage when it is not life threatening.
authors.affiliation: Center for Endocrine Surgery, Institute for Endocrinology, Clinical Centre of Serbia, Belgrade, Serbia.
authors.forename: B
authors.initials: B
authors.lastname: Bukvic
authors.forename: S
authors.initials: S
authors.lastname: Sipetic
authors.forename: N
authors.initials: N
authors.lastname: Kalezic
authors.forename: A
authors.initials: A
authors.lastname: Diklic
authors.forename: I
authors.initials: I
authors.lastname: Paunovic
authors.forename: B
authors.initials: B
authors.lastname: Kovacevic
authors.forename: A
authors.initials: A
authors.lastname: Knezevic
authors.forename: V
authors.initials: V
authors.lastname: Zivaljevic
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D009026:Mortality / Q000639:trends*; D011379:Prognosis; D055771:Serbia / Q000453:epidemiology; D015996:Survival Rate; D013964:Thyroid Neoplasms / Q000453:epidemiology / Q000401:mortality*; D013997:Time Factors; D055815:Young Adult