title: Retro-mode imaging of fibrovascular membrane in proliferative diabetic retinopathy after intravitreal bevacizumab injection.
abstract: The F10 is a new commercially available scanning laser confocal ophthalmoscope (SLO) that can perform multiple functions. We determined the usefulness of noninvasive evaluation of proliferative diabetic retinopathy (PDR) pathologies before and after intravitreal injection of bevacizumab (IVB) using the new indirect viewing system of the retro-mode function of the F10 SLO, and compared the images histologically with surgically excised fibrovascular membrane from two cases. In PDR, neovascular vessels in fibrovascular membrane were clearly seen with the retro-mode, even after IVB and without blood flow. The F10 SLO may be useful in evaluating neovascular vessels in fibrovascular membrane in PDR and for determining the precise retinal changes in diabetic retinopathy.
authors.affiliation: Department of Ophthalmology and Visual Sciences, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan.
authors.forename: Kiyoshi
authors.initials: K
authors.lastname: Suzuma
authors.forename: Eiko
authors.initials: E
authors.lastname: Tsuiki
authors.forename: Makiko
authors.initials: M
authors.lastname: Matsumoto
authors.forename: Azusa
authors.initials: A
authors.lastname: Fujikawa
authors.forename: Takashi
authors.initials: T
authors.lastname: Kitaoka