title: Investigation on acute toxicity and behavioral changes in Channa punctatus (Bloch) due to organophosphate pesticide profenofos.
abstract: Acute toxicity of an organophosphate pesticide profenofos (O-4-bromo-2- chlorophenyl-O-ethyl S-propyl phosphorothioate) to freshwater fish, Channa punctatus (Bloch), was studied in a static bioassay. Estimated 96-hour LC(50) of profenofos was found to be 2.68 μgL(-1). On the basis of the obtained LC(50) values for 96-hour exposure intervals, profenofos can be rated as highly toxic to C. punctatus. Fish exposed to profenofos showed hyper excitability, discoloration, erratic swimming, and secretion of excess amounts of mucus on the body and gills with eventual exhaustion and death.
authors.affiliation: Molecular Biology and Biotechnology Division, National Bureau of Fish Genetic Resources, Lucknow, India.
authors.forename: Atindra Kumar
authors.initials: AK
authors.lastname: Pandey
authors.forename: N S
authors.initials: NS
authors.lastname: Nagpure
authors.forename: Sunil P
authors.initials: SP
authors.lastname: Trivedi
authors.forename: Ravindra
authors.initials: R
authors.lastname: Kumar
authors.forename: Basdeo
authors.initials: B
authors.lastname: Kushwaha
authors.forename: Wazir S
authors.initials: WS
authors.lastname: Lakra
mesh_terms: D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects*; D007306:Insecticides / Q000737:chemistry / Q000633:toxicity*; D007928:Lethal Dose 50; D015394:Molecular Structure; D063086:Organothiophosphates / Q000737:chemistry / Q000633:toxicity*; D010473:Perciformes / Q000254:growth & development*; D016019:Survival Analysis; D023382:Toxicity Tests, Acute; D014874:Water Pollutants, Chemical / Q000737:chemistry / Q000633:toxicity*
chemical_list: D007306:Insecticides; D063086:Organothiophosphates; D014874:Water Pollutants, Chemical; C024273:profenofos