title: Rapid CE-UV binding tests of environmentally hazardous compounds with polymer-modified magnetic nanoparticles.
abstract: Hazardous compounds and bacteria in water have an adverse impact on human health and environmental ecology. Polydopamine (or polypyrrole)-coated magnetic nanoparticles and polymethacrylic acid-co-ethylene glycol dimethacrylate submicron particles were investigated for their fast binding kinetics with bisphenol A, proflavine, naphthalene acetic acid, and Escherichia coli. A new method was developed for the rapid determination of % binding by sequential injection of particles first and compounds (or E. coli) next into a fused-silica capillary for overlap binding during electrophoretic migration. Only nanolitre volumes of compounds and particles were sufficient to complete a rapid binding test. After heterogeneous binding, separation of the compounds from the particles was afforded by capillary electrophoresis. % binding was influenced by applied voltage but not current flow. In-capillary coating of particles affected the % binding of compounds.
authors.affiliation: Ottawa-Carleton Chemistry Institute, Department of Chemistry, Carleton University, Ottawa, ON, Canada.
authors.forename: Zafar
authors.initials: Z
authors.lastname: Iqbal
authors.forename: Samar
authors.initials: S
authors.lastname: Alsudir
authors.forename: Musharraf
authors.initials: M
authors.lastname: Miah
authors.forename: Edward P C
authors.initials: EP
authors.lastname: Lai
mesh_terms: D001559:Benzhydryl Compounds / Q000032:analysis / Q000737:chemistry / Q000378:metabolism; D019075:Electrophoresis, Capillary / Q000379:methods*; D004926:Escherichia coli / Q000737:chemistry / Q000378:metabolism; D015386:Hazardous Substances / Q000032:analysis* / Q000378:metabolism; D058185:Magnetite Nanoparticles / Q000737:chemistry*; D008956:Models, Chemical; D010636:Phenols / Q000032:analysis / Q000737:chemistry / Q000378:metabolism; D011109:Polymethacrylic Acids / Q000737:chemistry* / Q000378:metabolism; D011370:Proflavine / Q000032:analysis / Q000737:chemistry / Q000378:metabolism; D013056:Spectrophotometry, Ultraviolet; D000098826:Bisphenol A Compounds
chemical_list: D001559:Benzhydryl Compounds; D015386:Hazardous Substances; D058185:Magnetite Nanoparticles; D010636:Phenols; D011109:Polymethacrylic Acids; D011370:Proflavine; C497090:poly((ethylene glycol dimethacrylate)-co-(methacrylic acid)); C006780:bisphenol A; D000098826:Bisphenol A Compounds