title: The influence of prior obstetrical history on current 17-hydroxyprogesterone caproate use.
abstract: OBJECTIVE
  To determine if gestational age of prior preterm delivery influences a woman's receipt of 17-hydroxyprogesterone caproate (17-OHP-C).
  
  
  METHODS
  Retrospective cohort of women eligible for 17-OHP-C at Duke Obstetrics Clinic were identified by medical record review. Sociodemographic and clinical characteristics were abstracted. Results. Of 104 eligible subjects, 82 (78.8%) were offered 17-OHP-C. Of these, thirty-four (41.5%) declined. The median gestational age of the most recent preterm delivery was significantly lower among subjects who accepted 17-OHP-C as compared to those who declined (28.7 vs. 34.0 weeks, P = .02) and in subjects offered 17-OHP-C compared to those not offered 17-OHP-C (30.2 vs. 36.0 weeks, P = .03). Subjects not offered 17-OHP-C were more likely to have had an interval term delivery (31.8% vs. 9.7%, P = .009)
  
  
  CONCLUSIONS
  Women with earlier preterm deliveries were more likely to be offered and accept 17-OHP-C. Prior obstetric history may influence both providers' and patients' willingness to discuss and/or accept 17-OHP-C.
authors.affiliation: Department of Obstetrics and Gynecology, Duke University Medical Center (DUMC), P.O. Box 3967, Durham, NC 27710, USA. carla.ransom@duke.edu
authors.forename: Carla E
authors.initials: CE
authors.lastname: Ransom
authors.forename: Jeanette R
authors.initials: JR
authors.lastname: Chin
authors.forename: Hilary A
authors.initials: HA
authors.lastname: Roeder
authors.forename: Tammy R
authors.initials: TR
authors.lastname: Sinclair
authors.forename: R Phillips
authors.initials: RP
authors.lastname: Heine
authors.forename: Amy P
authors.initials: AP
authors.lastname: Murtha
mesh_terms: D000077713:17 alpha-Hydroxyprogesterone Caproate; D000328:Adult; D005260:Female; D005865:Gestational Age; D006801:Humans; D006908:Hydroxyprogesterones / Q000627:therapeutic use*; D010342:Patient Acceptance of Health Care / Q000523:psychology*; D010818:Practice Patterns, Physicians'; D011247:Pregnancy; D018566:Pregnancy, High-Risk; D047928:Premature Birth / Q000517:prevention & control* / Q000523:psychology; D011372:Progestins / Q000627:therapeutic use*; D012189:Retrospective Studies; D055502:Secondary Prevention; D047929:Term Birth / Q000523:psychology; D016312:Treatment Refusal / Q000523:psychology; D055815:Young Adult
chemical_list: D006908:Hydroxyprogesterones; D011372:Progestins; D000077713:17 alpha-Hydroxyprogesterone Caproate