title: 21-(4-Methyl-phenyl-sulfon-yl)-4,7,13,16-tetra-oxa-1,10,21-triaza-bicyclo-[8.8.5]tricosane-19,23-dione: an N-tosyl-ated macrobicyclic dilactam.
abstract: The macrobicyclic title compound, C(23)H(35)N(3)O(8)S, contains two tertiary amide bridgehead N atoms and a toluene-sulfonamide N atom in the center of the five-atom bridging strand. The mol-ecule has a central cavity that is defined by the 18-membered ring identified by the N(2)O(4) donor atom set and two 15-membered rings with N(3)O(2) donor atom sets. The toluene-sulfonamide N atom adopts an exo orientation with respect to the central cavity, and the tosyl group is oriented on one side of the aza-bridging strand that connects the bridgehead N atoms.
authors.affiliation: University of Oklahoma, Department of Chemistry and Biochemistry, 101 Stephenson Pkwy, Norman, OK 73019-5251, USA.
authors.forename: Trevor K
authors.initials: TK
authors.lastname: Ellis
authors.forename: Stephen M
authors.initials: SM
authors.lastname: Clayton
authors.forename: Douglas R
authors.initials: DR
authors.lastname: Powell
authors.forename: Richard W
authors.initials: RW
authors.lastname: Taylor