title: An epidemiological study of asymptomatic neurocysticercosis in a pig farming community in northern India.
abstract: Neurocysticercosis (NCC) is the most frequent parasitic infection of the central nervous system caused by the larvae of Taenia solium. The prevalence of NCC is obscured due to variations in the methods used for epidemiological studies and often asymptomatic manifestation. The present study was conducted on 595 apparently healthy individuals belonging to the pig farming community of northern India to estimate the prevalence of asymptomatic NCC and to evaluate risk factors based on questionnaires. Diagnosis of NCC was based on neuroimaging, immunological and epidemiological criteria. Asymptomatic NCC was detected in 90 (15.1%) of 595 individuals. The evaluation of risk factors showed that age >15 years (P=0.001), intake of raw vegetables (P=0.025) and undercooked pork (P=0.005), lack of safe drinking water (P=0.003), inadequate drainage system (P=0.049), no separate place for pigs (P≤0.001), NCC related active epilepsy in the family (P≤0.001) were significantly associated with asymptomatic NCC. The present study shows high prevalence of asymptomatic NCC in pig farming community of northern India. Further, asymptomatic NCC is associated with most variables of poor socio-economic parameters.
authors.affiliation: Department of Microbiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow-226014, India. knprasad@sgpgi.ac.in
authors.forename: Kashi N
authors.initials: KN
authors.lastname: Prasad
authors.forename: Avantika
authors.initials: A
authors.lastname: Verma
authors.forename: Sandeep
authors.initials: S
authors.lastname: Srivastava
authors.forename: Rakesh K
authors.initials: RK
authors.lastname: Gupta
authors.forename: Chandra M
authors.initials: CM
authors.lastname: Pandey
authors.forename: Vimal K
authors.initials: VK
authors.lastname: Paliwal
mesh_terms: D000293:Adolescent; D000328:Adult; D000822:Animal Husbandry / Q000592:standards*; D000818:Animals; D001921:Brain / Q000469:parasitology*; D004827:Epilepsy / Q000453:epidemiology* / Q000469:parasitology; D005260:Female; D006801:Humans; D007194:India / Q000453:epidemiology; D008279:Magnetic Resonance Imaging; D008297:Male; D008460:Meat / Q000469:parasitology*; D020019:Neurocysticercosis / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology*; D015995:Prevalence; D012307:Risk Factors; D011795:Surveys and Questionnaires; D013552:Swine; D041201:Taenia solium; D055815:Young Adult