title: Adhesive microarrays for multipurpose diagnostic tools.
abstract: We are reporting here a new technology for the straightforward production of integrated microarrays. The approach is based on the use of adhesive supports enabling (i) the immobilization of biomolecules as microarrays (up to 2500 spots per cm(2)) and (ii) the easy assembly of these microarrays with complex 3D structures such as 96-well bottomless microplates or polymer and glass microfluidic networks. The analytical performances of the system were demonstrated for sandwich protein detection (C-reactive protein) and hybridization assays, both in classical 96-well microplate format and microfluidic environment.
authors.affiliation: Laboratoire de Génie Enzymatique, Membranes Biomimétiques et Assemblages Supramoléculaires, Institut de Chimie et Biochimie Moléculaire et Supramoléculaire, Université Lyon1, CNRS 5246 ICBMS, Bat. CPE, 43 Bd du 11 Nov., 69622 Villeurbanne, France.
authors.forename: Benjamin P
authors.initials: BP
authors.lastname: Corgier
authors.forename: Céline A
authors.initials: CA
authors.lastname: Mandon
authors.forename: Gaelle C
authors.initials: GC
authors.lastname: Le Goff
authors.forename: Loïc J
authors.initials: LJ
authors.lastname: Blum
authors.forename: Christophe A
authors.initials: CA
authors.lastname: Marquette
mesh_terms: D002097:C-Reactive Protein / Q000032:analysis; D005898:Glass / Q000737:chemistry; D046210:Microfluidic Analytical Techniques / Q000295:instrumentation / Q000379:methods; D020411:Oligonucleotide Array Sequence Analysis / Q000295:instrumentation / Q000379:methods; D011108:Polymers / Q000737:chemistry; D040081:Protein Array Analysis / Q000295:instrumentation* / Q000379:methods
chemical_list: D011108:Polymers; D002097:C-Reactive Protein