title: A Malignant Gastrointestinal Stromal Tumor of the Gallbladder Immunoreactive for PDGFRA and Negative for CD 117 Antigen (c-KIT).
abstract: Gastrointestinal stromal tumors (GISTs) compose the largest category of well-recognized nonepithelial neoplasms of the gastrointestinal tract (GI). GISTs of the gallbladder are extremely rare tumors. Only four malignant, two benign and one GIST-like tumor of the gall bladder have ever been described. The four malignant GISTs were all positive for CD 117 antigen (c-kit). We present for the first time a malignant gastrointestinal stromal tumor of the gallbladder, immunoreactive for platelet-derived growth factor receptor alpha (PDGFRA) and negative for CD 117 antigen (c-KIT).
authors.affiliation: Department of Hepatobilary Surgery, Churchill Hospital, Oxford OX3 7LJ, UK.
authors.forename: Athanasios
authors.initials: A
authors.lastname: Petrou
authors.forename: Pari
authors.initials: P
authors.lastname: Alexandrou
authors.forename: Alexandros
authors.initials: A
authors.lastname: Papalambros
authors.forename: Angelica
authors.initials: A
authors.lastname: Saetta
authors.forename: Paraskevi
authors.initials: P
authors.lastname: Fragkou
authors.forename: Michalis
authors.initials: M
authors.lastname: Kontos
authors.forename: Nicholas
authors.initials: N
authors.lastname: Brennan
authors.forename: Antonio
authors.initials: A
authors.lastname: Manzelli
authors.forename: Kostantinos
authors.initials: K
authors.lastname: Bramis
authors.forename: Evangelos
authors.initials: E
authors.lastname: Felekouras