title: [The research of saffold virus in children with lower respiratory tract infection in Changsha].
abstract: OBJECTIVE
  To investigate prevalence of Saffold virus (SAFV) in Changsha area of hospitalized children with respiratory tract infection, and to discuss whether this virus is related to respiratory tract infection of children.
  
  
  METHODS
  643 nasopharyngeal aspirates samples were collected from hospitalized children with respiratory tract infection of the first affiliated hospital of Hunan nomal university during Nov. 2007 to Oct. 2008. Real-time fluorescent quanti-tative PCR(FQ-PCR) performed to screen the 5'UTR gene. And then analyze clinical data.
  
  
  RESULTS
  SAFV were detected in 67 patients (10.42%) out of the 643 children, it was not detected over 5 years of age. The virus were detected in 8 patients (25.81%) out of the 31 children with persistent pneumonia and chronic pneumonia, there was statistically significant.
  
  
  CONCLUSIONS
  There existed SAFV infection in hospitalized children with lower respiratory infection in Changsha area; SAFV maybe related to disease onset with lower respiratory tract infection of children.
authors.affiliation: The First Affiliated Hospital of Hunan Nomal University, Changsha 410000, China.
authors.forename: Qiong-hua
authors.initials: QH
authors.lastname: Zhou
authors.forename: Bing
authors.initials: B
authors.lastname: Zhang
authors.forename: Zhi-ping
authors.initials: ZP
authors.lastname: Xie
authors.forename: Han-chun
authors.initials: HC
authors.lastname: Gao
authors.forename: Ming-wei
authors.initials: MW
authors.lastname: Guo
authors.forename: Fei
authors.initials: F
authors.lastname: Zhang
authors.forename: Kun-long
authors.initials: KL
authors.lastname: Yan
authors.forename: Rong-fang
authors.initials: RF
authors.lastname: Zhang
authors.forename: Jing
authors.initials: J
authors.lastname: Zhang
authors.forename: Chang-qing
authors.initials: CQ
authors.lastname: Cao
authors.forename: Zhao-jun
authors.initials: ZJ
authors.lastname: Duan
mesh_terms: D000293:Adolescent; D017943:Cardiovirus / Q000235:genetics / Q000302:isolation & purification*; D002648:Child; D002675:Child, Preschool; D002681:China; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D016133:Polymerase Chain Reaction; D012141:Respiratory Tract Infections / Q000821:virology*