title: Correlates of mobility limitation in African Americans.
abstract: BACKGROUND
  This study identified demographic and health-related characteristics that were related to mobility limitation in a sample of community-dwelling African Americans.
  
  
  METHODS
  The sample consisted of 602 community-dwelling African-American men and women ages 48-92 years at study inception. Participants who reported being limited "a lot" or "a little" in climbing one flight of stairs or walking several blocks were considered to have mobility limitation. Logistic regression was conducted to estimate the independent effect of each demographic and health-related characteristic on odds of mobility limitation.
  
  
  RESULTS
  African Americans who reported two or more medical conditions had higher odds of mobility limitation (women: odds ratio = 3.52; 95% confidence interval: 1.89-6.53 and men: odds ratio = 2.53; 95% confidence interval: 1.10-5.85) than those who reported one or fewer medical conditions. African Americans with major depressive symptoms had higher odds of mobility limitation (women: odds ratio = 2.98; 95% confidence interval: 1.55-5.71 and men: odds ratio = 3.19; 95% confidence interval: 1.33-7.65) than those without major depressive symptoms.
  
  
  CONCLUSIONS
  These results highlight the importance of creating interventions particularly focused on chronic disease prevention and management for African American men and women during midlife to attempt to delay the onset or impede the progression of mobility problems that will likely become exacerbated in late life and severely affect the quality of life.
authors.affiliation: Hopkins Center for Health Disparities Solutions, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA. rthorpe@jhsph.edu
authors.forename: Roland J
authors.initials: RJ
authors.lastname: Thorpe
authors.forename: Olivio J
authors.initials: OJ
authors.lastname: Clay
authors.forename: Sarah L
authors.initials: SL
authors.lastname: Szanton
authors.forename: Jason C
authors.initials: JC
authors.lastname: Allaire
authors.forename: Keith E
authors.initials: KE
authors.lastname: Whitfield
mesh_terms: D001741:Black or African American; D000368:Aged; D000369:Aged, 80 and over; D002908:Chronic Disease; D015897:Comorbidity; D003430:Cross-Sectional Studies; D018450:Disease Progression; D005260:Female; D015577:Geriatric Assessment; D006801:Humans; D016015:Logistic Models; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D051346:Mobility Limitation; D016017:Odds Ratio; D011788:Quality of Life