title: Incidence and predictors of advance care planning among persons with cognitive impairment.
abstract: OBJECTIVE
  Persons with mild cognitive impairment (MCI) and Alzheimer disease (AD) are at heightened risk for future decisional incapacity. We sought to characterize advance care planning (ACP) rates over time in individuals who had no advance directives (living will or durable power of attorney) in place when they initially presented for a cognitive evaluation.
  
  
  METHODS
  Retrospective analysis of data that had been prospectively collected.
  
  
  METHODS
  Alzheimer's Disease Research Center memory disorders clinic.
  
  
  METHODS
  Persons (N = 127) with a diagnosis of MCI or early AD (n = 72) or moderate to severe AD (n = 55) and no advance directives upon initial presentation for a cognitive evaluation.
  
  
  METHODS
  Extraction of responses to items pertaining to ACP assessed during annual semistructured interviews.
  
  
  RESULTS
  By 5 years of follow-up, 39% of the sample had initiated ACP, with little difference by baseline diagnosis. Younger subjects (younger than 65 years) were significantly more likely to initiate advance directives (43%) than older subjects (37%). This age effect was more pronounced in men than in women as well as in married subjects, those with a family history of dementia, those with no depressive disorder, and subjects with moderate to severe AD (versus those with MCI or early AD) at baseline.
  
  
  CONCLUSIONS
  Only a minority of subjects initiated ACP. The findings suggest the need for interventions aimed at enhancing ACP completion rates, particularly among older adults with cognitive impairment, since these individuals may have a time-limited opportunity to plan for future medical, financial, and other major life decisions.
authors.affiliation: Department of Health and Community Systems, University of Pittsburgh, PA 15261, USA. ligst4@pitt.edu
authors.forename: Linda
authors.initials: L
authors.lastname: Garand
authors.forename: Mary Amanda
authors.initials: MA
authors.lastname: Dew
authors.forename: Jennifer H
authors.initials: JH
authors.lastname: Lingler
authors.forename: Steven T
authors.initials: ST
authors.lastname: DeKosky
mesh_terms: D032722:Advance Care Planning; D016223:Advance Directives / Q000523:psychology*; D000368:Aged; D000544:Alzheimer Disease / Q000175:diagnosis / Q000453:epidemiology; D003072:Cognition Disorders / Q000175:diagnosis / Q000453:epidemiology*; D003863:Depression / Q000175:diagnosis; D005260:Female; D005500:Follow-Up Studies; D015577:Geriatric Assessment; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D010414:Pennsylvania; D012189:Retrospective Studies