title: Valvular heart disease in pregnancy: maternal and fetal outcome.
abstract: The aim of this study was to evaluate the maternal and fetal outcome of pregnancy in Valvular Heart Disease (VHD). A better understanding of the effects of valvular abnormalities on pregnancy outcome is of value for risk assessment and the design of a therapeutic plan from the available information of a series of patient. A multicenter prospective study was carried out over a period of 5 years (2005-2009) involving 60 pregnant patients with valvular heart disease. Thirty eight patients (64%) had single valve involvement and mitral stenosis was the most predominant lesion (50%). Ten patients (16.7%) had undergone interventional and surgical correction prior to the pregnancy. Fourteen (24%) patients were identified as a NYHA class III-IV. Women with VHD had 8.35% pulmonary edema, 15.03% developed different types arrhythmia. The incidence of preterm birth and small for gestational age newborn was 11.69% and 13.36% respectively. There was one (1.67%) maternal death. Pregnancy in women with valvular heart disease is associated with remarkable unfavourable effect on maternal and fetal outcome which are related to severity of disease.
authors.affiliation: Department of Gynae and Obstetrics, Bangabandhu Sheikh Mujib Medical University, Shahbagh, Dhaka, Bangladesh.
authors.forename: N
authors.initials: N
authors.lastname: Akhter
authors.forename: F
authors.initials: F
authors.lastname: Rahman
authors.forename: M
authors.initials: M
authors.lastname: Salman
authors.forename: K
authors.initials: K
authors.lastname: Anam
authors.forename: N
authors.initials: N
authors.lastname: Begum
authors.forename: S
authors.initials: S
authors.lastname: Naher
authors.forename: N
authors.initials: N
authors.lastname: Fatema
authors.forename: Z
authors.initials: Z
authors.lastname: Hasan
authors.forename: M A
authors.initials: MA
authors.lastname: Rashid
authors.forename: S K
authors.initials: SK
authors.lastname: Benerjee
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D005865:Gestational Age; D006333:Heart Failure / Q000209:etiology*; D006349:Heart Valve Diseases / Q000150:complications*; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D007236:Infant, Small for Gestational Age; D008943:Mitral Valve; D011247:Pregnancy; D011248:Pregnancy Complications; D055815:Young Adult