title: Sex steroid hormones and reproductive disorders: impact on women's health.
abstract: The role of sex steroid hormones in reproductive function in women is well established. However, in the last two decades it has been shown that receptors for estrogens, progesterone and androgens are expressed in non reproductive tissue /organs (bone, brain, cardiovascular system) playing a role in their function. Therefore, it is critical to evaluate the impact of sex steroid hormones in the pathophysiology of some diseases (osteoporosis, Alzheimer, atherosclerosis). In particular, women with primary ovarian insufficiency, polycystic ovary syndrome, endometriosis and climacteric syndrome may have more health problems and therefore an hormonal treatment may be crucial for these women.
authors.affiliation: 1Department of Reproductive Medicine and Gynecology, University Medical Center, Utrecht, Netherlands.
authors.forename: Bart C J M
authors.initials: BC
authors.lastname: Fauser
authors.forename: Joop S E
authors.initials: JS
authors.lastname: Laven
authors.forename: Basil C
authors.initials: BC
authors.lastname: Tarlatzis
authors.forename: Kelle H
authors.initials: KH
authors.lastname: Moley
authors.forename: Hilary O D
authors.initials: HO
authors.lastname: Critchley
authors.forename: Robert N
authors.initials: RN
authors.lastname: Taylor
authors.forename: Sarah L
authors.initials: SL
authors.lastname: Berga
authors.forename: Paul G
authors.initials: PG
authors.lastname: Mermelstein
authors.forename: Paul
authors.initials: P
authors.lastname: Devroey
authors.forename: Luca
authors.initials: L
authors.lastname: Gianaroli
authors.forename: Thomas
authors.initials: T
authors.lastname: D'Hooghe
authors.forename: Paolo
authors.initials: P
authors.lastname: Vercellini
authors.forename: Lone
authors.initials: L
authors.lastname: Hummelshoj
authors.forename: Susan
authors.initials: S
authors.lastname: Rubin
authors.forename: Angelique J
authors.initials: AJ
authors.lastname: Goverde
authors.forename: Vincenzo
authors.initials: V
authors.lastname: De Leo
authors.forename: Felice
authors.initials: F
authors.lastname: Petraglia
mesh_terms: D004715:Endometriosis / Q000503:physiopathology*; D005260:Female; D012739:Gonadal Steroid Hormones / Q000502:physiology*; D006801:Humans; D011085:Polycystic Ovary Syndrome / Q000503:physiopathology*; D017698:Postmenopause / Q000502:physiology*; D016649:Primary Ovarian Insufficiency / Q000503:physiopathology*
chemical_list: D012739:Gonadal Steroid Hormones