title: Developmental genetics in Xenopus tropicalis.
abstract: The diploid pipid frog Xenopus tropicalis has recently emerged as a powerful new model system for combining genetic and genomic analysis of tetrapod development with embryological and biochemical assays. Its early development closely resembles that of its well-understood tetraploid relative Xenopus laevis, from which techniques and reagents can be readily transferred, but its compact genome is highly syntenic with those of amniotes. Genetic approaches are facilitated by the large number of embryos produced and the ease of haploid genetics and gynogenesis.
authors.affiliation: National Institute for Medical Research, London, UK.
authors.forename: Timothy J
authors.initials: TJ
authors.lastname: Geach
authors.forename: Lyle B
authors.initials: LB
authors.lastname: Zimmerman
mesh_terms: D000818:Animals; D001947:Breeding; D002503:Centromere / Q000235:genetics; D015925:Cryopreservation; D018076:DNA, Complementary / Q000235:genetics; D004625:Embryo, Nonmammalian / Q000378:metabolism; D005260:Female; D005307:Fertilization in Vitro; D008040:Genetic Linkage; D005819:Genetic Markers / Q000235:genetics; D005821:Genetic Techniques; D023281:Genomics; D005838:Genotype; D006238:Haploidy; D007621:Karyotyping; D008297:Male; D016296:Mutagenesis; D009154:Mutation; D010641:Phenotype; D020641:Polymorphism, Single Nucleotide / Q000235:genetics; D012100:Reproduction, Asexual; D016622:Silver Staining; D013094:Spermatozoa / Q000378:metabolism; D020858:Tissue and Organ Harvesting; D014981:Xenopus / Q000196:embryology / Q000235:genetics* / Q000254:growth & development* / Q000502:physiology
chemical_list: D018076:DNA, Complementary; D005819:Genetic Markers