title: Renal cocktail: too hard for a diabetic.
abstract: We herein report a case of a 67-year-old diabetic woman who presented with a history of fatigue for 1 month. Her investigations showed proteinuria, active urine sediment, p-ANCA positivity and worsened renal functions. A diagnosis of rapidly progressive glomerulonephritis was made. Renal biopsy revealed class V (membranous) lupus nephritis with superimposed ANCA-associated crescentic glomerulonephritis. She was treated with steroids and cyclophosphamide. Two months later, she presented with cytomegalovirus colitis and deep vein thrombosis of right leg. The case reflects an interesting renal pathology, and complications of the disease per se and its treatment.
authors.affiliation: Department of Nephrology, The Ottawa Hospital (University of Ottawa), Riverside Campus 1967 prom. Riverside Drive, Ottawa, ON, K1H 7W9, Canada. parthankur@yahoo.com
authors.forename: Ankur
authors.initials: A
authors.lastname: Gupta
authors.forename: Mohan
authors.initials: M
authors.lastname: Biyani
authors.forename: Susan J
authors.initials: SJ
authors.lastname: Robertson
mesh_terms: D000368:Aged; D019268:Antibodies, Antineutrophil Cytoplasmic / Q000032:analysis; D001706:Biopsy; D048909:Diabetes Complications / Q000150:complications* / Q000175:diagnosis; D005260:Female; D005500:Follow-Up Studies; D005921:Glomerulonephritis / Q000175:diagnosis / Q000209:etiology*; D015433:Glomerulonephritis, Membranous / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D007668:Kidney / Q000473:pathology*; D008181:Lupus Nephritis / Q000175:diagnosis / Q000209:etiology*
chemical_list: D019268:Antibodies, Antineutrophil Cytoplasmic