title: Endometrial intestinal metaplasia: a report of two cases, including one associated with cervical intestinal and pyloric metaplasia.
abstract: Intestinal metaplasia of the endometrium is extremely uncommon with only a single earlier case report. We describe 2 cases of endometrial intestinal metaplasia, one of them involving an endometrial polyp, characterized by the presence of intestinal-type epithelium containing goblet and neuroendocrine cells, which were positive with CK20, CDX2, chromogranin, and villin. In 1 case, there was concomitant intestinal and pyloric metaplasia in the endocervix. Together with the observation of the earlier reported case of endometrial intestinal metaplasia, there was also intestinal metaplasia in the cervix. This suggests a possible association between intestinal metaplasia at different sites in the female genital tract.
authors.affiliation: Pathology Department of San Cecilio University Hospital, Avenida Madrid 11, Granada, Spain.
authors.forename: Alina
authors.initials: A
authors.lastname: Nicolae
authors.forename: Pablo
authors.initials: P
authors.lastname: Goyenaga
authors.forename: W Glenn
authors.initials: WG
authors.lastname: McCluggage
authors.forename: Ovidiu
authors.initials: O
authors.lastname: Preda
authors.forename: Francisco F
authors.initials: FF
authors.lastname: Nogales
mesh_terms: D000368:Aged; D002584:Cervix Uteri / Q000473:pathology*; D004717:Endometrium / Q000473:pathology*; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D007413:Intestinal Mucosa / Q000473:pathology*; D008679:Metaplasia; D008875:Middle Aged; D011708:Pylorus / Q000473:pathology*