title: 2-Lithiated-2-phenyloxetane: a new attractive synthon for the preparation of oxetane derivatives.
abstract: A valuable and direct method to access 2-substituted-2-phenyloxetanes by electrophilic quenching of the corresponding 2-lithiated derivative has, for the first time, been described. 2-Lithiated-2-phenyloxetane was found to be configurationally unstable. Evidence is presented to show that electron-transfer processes are also operative in the coupling reactions with electrophiles.
authors.affiliation: Dipartimento Farmaco-Chimico, Università di Bari Aldo Moro, Consorzio Interuniversitario Nazionale Metodologie e Processi Innovativi di Sintesi CINMPIS, Bari, Italy.
authors.forename: Donato Ivan
authors.initials: DI
authors.lastname: Coppi
authors.forename: Antonio
authors.initials: A
authors.lastname: Salomone
authors.forename: Filippo Maria
authors.initials: FM
authors.lastname: Perna
authors.forename: Vito
authors.initials: V
authors.lastname: Capriati
mesh_terms: D060326:Chemistry Techniques, Synthetic / Q000379:methods*; D004988:Ethers, Cyclic / Q000138:chemical synthesis* / Q000737:chemistry*; D008094:Lithium / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D004988:Ethers, Cyclic; D008094:Lithium; C005287:oxetane