title: Primary HIV infection with acute transverse myelitis.
abstract: Primary HIV infection (PHI) is associated with various neurological disorders. However, acute transverse myelitis (ATM) complicating PHI has not been reported after the introduction of the combination antiretroviral therapy (cART). We encountered one patient with known PHI with clinical presentation of ATM. Treatment with cART and corticosteroids successfully improved symptoms, and no recurrence was noted after discontinuation of cART. In conclusion, concurrent use of cART and corticosteroids was effective against PHI accompanied by ATM and could be withdrawn after improvement of ATM.
authors.affiliation: AIDS Clinical Center, National Center for Global Health and Medicine, Japan. yhamada@acc.ncgm.go.jp
authors.forename: Yohei
authors.initials: Y
authors.lastname: Hamada
authors.forename: Koji
authors.initials: K
authors.lastname: Watanabe
authors.forename: Takahiro
authors.initials: T
authors.lastname: Aoki
authors.forename: Noritoshi
authors.initials: N
authors.lastname: Arai
authors.forename: Miwako
authors.initials: M
authors.lastname: Honda
authors.forename: Yoshimi
authors.initials: Y
authors.lastname: Kikuchi
authors.forename: Shinichi
authors.initials: S
authors.lastname: Oka
mesh_terms: D000328:Adult; D023241:Antiretroviral Therapy, Highly Active; D015658:HIV Infections / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D008297:Male; D008775:Methylprednisolone / Q000627:therapeutic use; D009188:Myelitis, Transverse / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D016896:Treatment Outcome
chemical_list: D008775:Methylprednisolone