title: Successful use of hirudin during cardiac surgery using minimized extracorporeal circulation in patients with heparin-induced thrombocytopenia.
abstract: In this case series, we describe our successful use of a reduced hirudin dosage as an anticoagulant during cardiac surgery using minimized extracorporeal circulation in patients with heparin-induced thrombocytopenia.
authors.affiliation: Department of Cardiothoracic Surgery, Medical Center University Regensburg, Regensburg, Germany. assadhaneya@web.de
authors.forename: Assad
authors.initials: A
authors.lastname: Haneya
authors.forename: Alois
authors.initials: A
authors.lastname: Philipp
authors.forename: Karla
authors.initials: K
authors.lastname: Lehle
authors.forename: Claudius
authors.initials: C
authors.lastname: Diez
authors.forename: Leopold
authors.initials: L
authors.lastname: Rupprecht
authors.forename: Reinhard
authors.initials: R
authors.lastname: Kobuch
authors.forename: Stephan W
authors.initials: SW
authors.lastname: Hirt
authors.forename: York A
authors.initials: YA
authors.lastname: Zausig
authors.forename: Christof
authors.initials: C
authors.lastname: Schmid
authors.forename: Thomas
authors.initials: T
authors.lastname: Puehler
mesh_terms: D000368:Aged; D000925:Anticoagulants / Q000009:adverse effects*; D016063:Blood Loss, Surgical / Q000517:prevention & control; D001804:Blood Transfusion, Autologous; D001026:Coronary Artery Bypass / Q000379:methods*; D017707:Erythrocyte Transfusion; D005112:Extracorporeal Circulation / Q000295:instrumentation*; D005260:Female; D005343:Fibrinolytic Agents / Q000008:administration & dosage* / Q000097:blood; D006493:Heparin / Q000009:adverse effects*; D006629:Hirudins / Q000008:administration & dosage* / Q000097:blood; D006801:Humans; D008297:Male; D008875:Middle Aged; D016343:Monitoring, Intraoperative; D010314:Partial Thromboplastin Time; D010949:Plasma; D011182:Postoperative Care; D011994:Recombinant Proteins / Q000008:administration & dosage / Q000097:blood; D013921:Thrombocytopenia / Q000097:blood / Q000139:chemically induced*; D014914:Whole Blood Coagulation Time
chemical_list: D000925:Anticoagulants; D005343:Fibrinolytic Agents; D006629:Hirudins; D011994:Recombinant Proteins; D006493:Heparin; C083544:lepirudin