title: Clinical applications of long-wavelength (1,000-nm) optical coherence tomography.
abstract: Commercial optical coherence tomography (OCT) instruments generally use light sources in the range of 800 to 860 nm. Although imaging with these light sources provides excellent visualization of the retinal architecture, details of structures and abnormalities below the retinal pigment epithelium are often limited. At the same time, the optimal light source wavelength for clinical OCT imaging is unknown. OCT imaging using longer wavelength light (1,050 nm) has several potential advantages, including less scattering with media opacity and deeper penetration. This article reviews the current state-of-the-art of long wavelength OCT imaging and explores potential clinical applications.
authors.affiliation: NIHR Biomedical Research Centre for Ophthalmology, Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, United Kingdom.
authors.forename: Pearse A
authors.initials: PA
authors.lastname: Keane
authors.forename: Humberto
authors.initials: H
authors.lastname: Ruiz-Garcia
authors.forename: Srinivas R
authors.initials: SR
authors.lastname: Sadda
mesh_terms: D003941:Diagnostic Techniques, Ophthalmological / Q000295:instrumentation*; D005128:Eye Diseases / Q000175:diagnosis*; D006801:Humans; D041623:Tomography, Optical Coherence / Q000295:instrumentation*