title: Transient and switchable (triethylsilyl)ethynyl protection of DNA against cleavage by restriction endonucleases.
authors.affiliation: Institute of Organic Chemistry and Biochemistry, Academy of Science Czech Republic, Gilead Sciences & IOCB Research Center, Flemingovo náměstí 2, Prague 6, 16610, Czech Republic.
authors.forename: Pavel
authors.initials: P
authors.lastname: Kielkowski
authors.forename: Hana
authors.initials: H
authors.lastname: Macíčková-Cahová
authors.forename: Radek
authors.initials: R
authors.lastname: Pohl
authors.forename: Michal
authors.initials: M
authors.lastname: Hocek
mesh_terms: D053837:DNA Cleavage / Q000187:drug effects*; D015252:Deoxyribonucleases, Type II Site-Specific / Q000037:antagonists & inhibitors* / Q000378:metabolism*; D004791:Enzyme Inhibitors / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*; D015394:Molecular Structure; D017646:Organosilicon Compounds / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*; D013237:Stereoisomerism; D013329:Structure-Activity Relationship
chemical_list: D004791:Enzyme Inhibitors; D017646:Organosilicon Compounds; D015252:Deoxyribonucleases, Type II Site-Specific