title: Determining the difference in medication compliance between the general patient population and patients receiving antihypertensive therapy: a case study.
abstract: This study addressed the issue of medication compliance in general, compliance with antihypertensive therapy, and the relationship between these two groups. In addition to determining the reasons for noncompliance with therapy prescription, the aim of this study was to also establish whether it was considered feasible by the patients to comply with their physician's instructions and whether the patients believed that the prescribed therapy was beneficial to their health. Hypertensive patients were compared to the total study population according to age groups. The study was designed as a cross-sectional survey with the use of a 33-item self-administered questionnaire. The study included 635 individuals who were collecting or buying drugs for the treatment of chronic diseases, with special reference to subjects taking antihypertensive agents (n = 361). More than half (n = 361; 56.9%) of the 635 study subjects were on therapy for arterial hypertension and possibly for some other diseases. The great majority of study subjects reported forgetfulness as the main reason for skipping drug doses. Comparison between the total study population and the subjects treated for arterial hypertension according to age groups (compliant, noncompliant and all together) yielded no statistically significant difference. We concluded that there was no difference in medication compliance between the general patient population and patients receiving antihypertensive therapy and there was no correlation between medication compliance and age.
authors.affiliation: Department of Pharmacoepidemiology, Andrija Stampar Institute of Public Health, Zagreb 10000, Croatia.
authors.forename: Josip
authors.initials: J
authors.lastname: Culig
authors.forename: Marcel
authors.initials: M
authors.lastname: Leppée
authors.forename: Jelena
authors.initials: J
authors.lastname: Boskovic
authors.forename: Mirela
authors.initials: M
authors.lastname: Eric
mesh_terms: D000328:Adult; D000368:Aged; D000959:Antihypertensive Agents / Q000627:therapeutic use*; D001294:Attitude to Health; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D010349:Patient Compliance / Q000706:statistics & numerical data*; D010820:Physicians; D011795:Surveys and Questionnaires; D017539:Tunica Intima / Q000473:pathology; D016903:Drug Monitoring
chemical_list: D000959:Antihypertensive Agents