title: Adverse events after mass azithromycin treatments for trachoma in Ethiopia.
abstract: During a cluster-randomized clinical trial for trachoma in Ethiopia, two rounds of adverse event surveillance were performed in a random sample of communities after community-wide mass azithromycin treatment. The prevalence of any reported adverse event ranged from 4.9% to 7.0% in children 1-9 years of age and from 17.0% to 18.7% in persons ≥ 10 years of age. Adverse events appeared to cluster by household and perhaps by village. Mass azithromycin distributions were well tolerated in this setting.
authors.affiliation: The Carter Center, Addis Ababa, Ethiopia.
authors.forename: Berhan
authors.initials: B
authors.lastname: Ayele
authors.forename: Teshome
authors.initials: T
authors.lastname: Gebre
authors.forename: Jenafir I
authors.initials: JI
authors.lastname: House
authors.forename: Zhaoxia
authors.initials: Z
authors.lastname: Zhou
authors.forename: Charles E
authors.initials: CE
authors.lastname: McCulloch
authors.forename: Travis C
authors.initials: TC
authors.lastname: Porco
authors.forename: Bruce D
authors.initials: BD
authors.lastname: Gaynor
authors.forename: Paul M
authors.initials: PM
authors.lastname: Emerson
authors.forename: Thomas M
authors.initials: TM
authors.lastname: Lietman
authors.forename: Jeremy D
authors.initials: JD
authors.lastname: Keenan
mesh_terms: D019072:Antibiotic Prophylaxis; D017963:Azithromycin / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D016000:Cluster Analysis; D005002:Ethiopia / Q000453:epidemiology; D005260:Female; D005767:Gastrointestinal Diseases / Q000139:chemically induced*; D006801:Humans; D007223:Infant; D008297:Male; D014141:Trachoma / Q000517:prevention & control*
chemical_list: D017963:Azithromycin