title: Vitamin C derivatives as new coreactants for tris(2,2'-bipyridine)ruthenium(II) electrochemiluminescence.
abstract: Vitamin C derivatives (VCDs) have been widely used as the alternative and stable sources of vitamin C, and accordingly exhibit many new applications, such as anti-tumor and central nervous system drug delivery. In this study, their Ru(bpy)(3)(2+) electrochemiluminescence (ECL) properties have been investigated for the first time using well-known ascorbyl phosphate and ascorbyl palmitate as representative VCDs. Ascorbyl phosphate and ascorbyl palmitate are VCDs with different substituted positions. Both of them increase Ru(bpy)(3)(2+) ECL, indicating that other VCDs may also enhance Ru(bpy)(3)(2+) ECL signal. The calibration plot for ascorbyl phosphate is linear from 3×10(-6) to 1.0×10(-3) M with a detection limit of 1.4×10(-6) M at a signal-to-noise ratio of 3. The relative standard deviation is 3.6% for six replicate measurements of 0.01mM ascorbyl 2-phosphate solution. The proposed method is about one order of magnitude more sensitive than electrochemical and UV-vis methods for the determination of ascorbyl phosphate, and is used successfully for the determination of ascorbyl phosphate in whitening and moisturising body wash.
authors.affiliation: State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin 130022, Chinadouglas.baxter@alsglobal.com.
authors.forename: Yali
authors.initials: Y
authors.lastname: Yuan
authors.forename: Haijuan
authors.initials: H
authors.lastname: Li
authors.forename: Shuang
authors.initials: S
authors.lastname: Han
authors.forename: Lianzhe
authors.initials: L
authors.lastname: Hu
authors.forename: Saima
authors.initials: S
authors.lastname: Parveen
authors.forename: Guobao
authors.initials: G
authors.lastname: Xu
mesh_terms: D015082:2,2'-Dipyridyl / Q000031:analogs & derivatives* / Q000737:chemistry; D001205:Ascorbic Acid / Q000031:analogs & derivatives / Q000032:analysis*; D002244:Carbon / Q000737:chemistry; D056831:Coordination Complexes; D055664:Electrochemical Techniques / Q000379:methods*; D004566:Electrodes; D008163:Luminescent Measurements / Q000379:methods*; D017975:Ruthenium Compounds
chemical_list: D015082:2,2'-Dipyridyl; D001205:Ascorbic Acid; D002244:Carbon; D056831:Coordination Complexes; C547232:tris(2,2-bipyridine)-ruthenium(II); D017975:Ruthenium Compounds; C011669:ascorbate-2-phosphate; C031226:6-O-palmitoylascorbic acid