title: [Fiftieth anniversary of the description of the chemical structure of antibodies].
abstract: The identification of the antitoxic property of serum in 1890 by Emil von Behring and the introduction of the term "Antikörper" by Paul Ehrlich in 1891 referring to one of the most relevant mechanisms of defense of the adaptive immune system, i.e., the humoral immune response mediators, mark the beginning of modern immunology. The "Y" structure was described 50 years ago by Gerald M. Edelman and Rodney R. Porter. Thus, on the fiftieth anniversary of the description of the chemical structure of antibodies, we consider it appropriate to celebrate this fact by sketching a brief outline and review of these epoch-making achievements.
authors.affiliation: Departamento de Inmunología y Reumatología, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, México DF, México.
authors.forename: Dolores
authors.initials: D
authors.lastname: Ramos-Bello
authors.forename: Luis
authors.initials: L
authors.lastname: Llorente