title: Surgical outcomes of hemorrhagic metastatic brain tumors.
abstract: OBJECTIVE
  Hemorrhagic metastatic brain tumors are not rare, but little is known about the surgical outcome following treatment. We conducted this study to determine the result of the surgical outcome of hemorrhagic metastatic brain tumors.
  
  
  METHODS
  From July 2001 to December 2008, 21 patients underwent surgery for hemorrhagic metastatic brain tumors at our institution. 15 patients had lung cancer, 3 had hepatocellular carcinoma, and the rest had rectal cancer, renal cell carcinoma, and sarcoma. 20 patients had macroscopic hemorrhage in the tumors, and one patient had intracerebral hemorrhage surrounding the tumor. A retrospective clinical review was conducted focusing on the patterns of presenting symptoms and signs, as well as local recurrence following surgery.
  
  
  RESULTS
  Among 21 hemorrhagic brain metastases, local recurrence developed in two patients. The 12 month progression free survival rate was 86.1%. Mean time to progression was 20.8 months and median survival time after surgery was 11.7 months.
  
  
  CONCLUSIONS
  The results of our study showed that hemorrhagic metastatic brain tumors rarely recurred after surgery. Surgery should be considered as a good treatment option for hemorrhagic brain metastasis, especially in cases with increased intracranial pressure or severe neurologic deficits.
authors.affiliation: Neuro-Oncology Clinic, National Cancer Center, Goyang, Korea.
authors.forename: Heon
authors.initials: H
authors.lastname: Yoo
authors.forename: Eugene
authors.initials: E
authors.lastname: Jung
authors.forename: Ho Shin
authors.initials: HS
authors.lastname: Gwak
authors.forename: Sang Hoon
authors.initials: SH
authors.lastname: Shin
authors.forename: Seung Hoon
authors.initials: SH
authors.lastname: Lee