title: Serial changes of fatty acids in preterm breast milk of Korean women.
abstract: Samples of breast milk were collected at postpartum weeks 1, 2, 4, 6, 8, and 12 from 104 Korean mothers who had delivered infants at less than 34 weeks or weighing less than 1.8 kg to investigate changes in fatty acid (FAs). Full-term breast milk (FBM) collected at the end of first week postpartum from 26 Korean women delivering healthy, term infants was used for comparison. Stability in relative FA composition was maintained during the first 3 months of lactation in preterm breast milk (PBM), and the relative composition of polyunsaturated FAs (PUFA), monounsaturated FAs, and saturated FAs remained constant in PBM. However, the ω6/ω3 ratio was significantly higher as lactation progressed owing to lower ω3 PUFA in PBM. The proportions of docosahexaenoic acid (DHA) and arachidonic acid (AA) in PBM gradually decreased over time, but the DHA/AA ratio was kept constant at 1.13, higher than that of Western countries. At the end of the first week, relative proportions of FAs were similar in PBM and FBM, but absolute concentrations of FA were higher in PBM.
authors.affiliation: Research Institute of Food and Nutritional Sciences, Yonsei University, Seoul, Korea.
authors.forename: Sung-Hee
authors.initials: SH
authors.lastname: Jang
authors.forename: Byong Sop
authors.initials: BS
authors.lastname: Lee
authors.forename: Jung Hwa
authors.initials: JH
authors.lastname: Park
authors.forename: Eun Jung
authors.initials: EJ
authors.lastname: Chung
authors.forename: Young Sook
authors.initials: YS
authors.lastname: Um
authors.forename: Yang Cha
authors.initials: YC
authors.lastname: Lee-Kim
authors.forename: Ellen Ai-Rhan
authors.initials: EA
authors.lastname: Kim
mesh_terms: D000328:Adult; D005227:Fatty Acids / Q000008:administration & dosage / Q000032:analysis*; D015525:Fatty Acids, Omega-3 / Q000032:analysis; D043371:Fatty Acids, Omega-6 / Q000032:analysis; D005231:Fatty Acids, Unsaturated / Q000008:administration & dosage / Q000032:analysis*; D005260:Female; D006801:Humans; D007223:Infant; D007227:Infant Nutritional Physiological Phenomena / Q000502:physiology*; D007231:Infant, Newborn; D007234:Infant, Premature; D007723:Korea; D008895:Milk, Human / Q000737:chemistry*
chemical_list: D005227:Fatty Acids; D015525:Fatty Acids, Omega-3; D043371:Fatty Acids, Omega-6; D005231:Fatty Acids, Unsaturated