title: Altered mandibular growth under functional posterior displacement in rats.
abstract: OBJECTIVE
  To test the null hypothesis that there is no difference in mandibular growth between growing rats with posterior functional mandibular displacement and growing rats without functional mandibular displacement.
  
  
  METHODS
  Twenty female Wistar rats (5 weeks old) were randomized into two groups: (1) control and (2) mandible posterior displacement in the occluded condition induced by an occlusal guiding appliance. After 8 weeks all animals were sacrificed, cone beam computed tomography scan images of the heads were taken using the classic I-CAT, and acrylic rapid-prototyped templates of the mandibles were constructed. Mandibular length, ramus height, and intercondylar distance were measured. Mandibular length and ramus height were submitted to the two-way analysis of variance, while intercondylar distance was analyzed by nonpaired Student's t-test.
  
  
  RESULTS
  Mandibular length was bigger (P < .0001) in the control than in the experimental group, but no significant difference was found between the left and right sides (P  =  .9380). No significant differences were observed for ramus height and intercondylar distance.
  
  
  CONCLUSIONS
  The results of this study demonstrated that functional posterior displacement of the mandible in growing rats resulted in shorter mandibular length.
authors.affiliation: Department of Prosthodontics and Periodontology, Piracicaba Dental School, State University of Campinas, Piracicaba, São Paulo, Brazil. saudeoral@yahoo.com.br
authors.forename: Arcelino
authors.initials: A
authors.lastname: Farias-Neto
authors.forename: Ana Paula Varela Brown
authors.initials: AP
authors.lastname: Martins
authors.forename: Sidney Raimundo
authors.initials: SR
authors.lastname: Figueroba
authors.forename: Francisco Carlos
authors.initials: FC
authors.lastname: Groppo
authors.forename: Solange Maria de
authors.initials: SM
authors.lastname: Almeida
authors.forename: Célia Marisa
authors.initials: CM
authors.lastname: Rizzatti-Barbosa
mesh_terms: D000818:Animals; D002508:Cephalometry; D005260:Female; D008310:Malocclusion / Q000503:physiopathology*; D008334:Mandible / Q000033:anatomy & histology / Q000254:growth & development*; D008445:Maxillofacial Development / Q000502:physiology*; D017090:Occlusal Splints; D009929:Organ Size; D009973:Orthodontics, Preventive; D016059:Range of Motion, Articular; D051381:Rats; D017208:Rats, Wistar; D018709:Statistics, Nonparametric; D013314:Stress, Mechanical; D013704:Temporomandibular Joint / Q000254:growth & development / Q000503:physiopathology*; D014057:Tomography, X-Ray Computed