title: Cystic sebaceous lymphadenoma of the parotid gland: case report and review of the literature.
abstract: Sebaceous lymphadenoma (SL) of the salivary glands is a very rare, benign tumour with distinct histopathologic characteristics and uncertain histogenesis. It is almost exclusively confined to the parotid gland where it occurs generally as a slowly growing mass in elderly patients. Several imaging techniques and fine-needle aspiration cytology (FNAC) can be used for diagnosis, but definitive diagnosis is usually established only by histopathological examination. Such lesions are composed of a varying admixture of islands, duct-like structures and cysts covered with squamous or cuboid and columnar epithelium intermingled with a background of lymphoid stroma, sometimes with lymph follicles. Accurate diagnosis of SL is important since many salivary masses in adults are malignant. We report a case of cystic sebaceous lymphadenoma of the left parotid gland surgically resected in a 70-year-old woman. Fifteen months after surgery, the patient is well, with no evidence of recurrence. Differential diagnostic problems and histogenetic considerations are provided; a comprehensive review of the literature has also been performed.
authors.affiliation: U.O. Anatomia Patologica, Ospedale di Vallecamonica, Esine (BS), Italy. s.squillaci@ospedalevallecamonica.it
authors.forename: S
authors.initials: S
authors.lastname: Squillaci
authors.forename: R
authors.initials: R
authors.lastname: Marchione
authors.forename: M
authors.initials: M
authors.lastname: Piccolomini
mesh_terms: D000235:Adenolymphoma / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D000368:Aged; D044963:Biopsy, Fine-Needle; D005260:Female; D006801:Humans; D053555:Keratin-5 / Q000378:metabolism; D008565:Membrane Proteins / Q000378:metabolism; D018396:Mucin-1 / Q000378:metabolism; D010307:Parotid Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D016896:Treatment Outcome
chemical_list: C081876:CKAP4 protein, human; D053555:Keratin-5; D008565:Membrane Proteins; D018396:Mucin-1