title: Development of quality assessment method for optically active food flavor chemicals.
abstract: A quality assessment method for commercially available, optically active flavor compounds, namely, menthol, menthyl acetate, borneol, perillaldehyde, and 1,8-cineol, was developed. A gas chromatograph equipped with a flame ionization detector and a DB-5ms capillary column was used for the chemical purity test. A GC/MS with a beta-DEX cyclodextrin column was used for the optical purity test, by which the enantiomeric separation of each flavor compound was achieved. Enantiomeric excess was calculated as an expression of optical purity. Of the 25 standard samples subjected to the chemical purity test, six were found to have lower purity than the data provided by the manufacturers. When the same samples were subjected to the optical purity test, 11 were found to have lower purity than that indicated on the reagent labels. These results suggest that there is a need to conduct an optical purity test, in addition to a chemical purity test, for the quality assessment of flavor standards.
authors.affiliation: Hoshi University, Faculty of Pharmaceutical Sciences, Department of Analytical Chemistry, 2-4-41 Ebara, Shinagawa-ku, Tokyo 142-8501. k-saito@hoshi.ac.jp
authors.forename: Koichi
authors.initials: K
authors.lastname: Saito
authors.forename: Kouhei
authors.initials: K
authors.lastname: Hosono
authors.forename: Nariko
authors.initials: N
authors.lastname: Kitazawa
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Iwasaki
authors.forename: Rie
authors.initials: R
authors.lastname: Ito
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Nakazawa
mesh_terms: D005421:Flavoring Agents / Q000737:chemistry*; D005504:Food Analysis / Q000379:methods*; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods*; D015394:Molecular Structure; D009904:Optical Rotation; D011786:Quality Control
chemical_list: D005421:Flavoring Agents