title: F33:A-:B- and F2:A-:B- plasmids mediate dissemination of rmtB-blaCTX-M-9 group genes and rmtB-qepA in Enterobacteriaceae isolates from pets in China.
abstract: This study investigated the prevalence of 16S rRNA methylase genes in 267 Enterobacteriaceae isolates collected from pets. The rmtB gene was detected in 69 isolates, most of which were clonally unrelated. The coexistence of the rmtB gene with the bla(CTX-M-9) group genes and/or qepA within the same IncFII replicons was commonly detected. The two dominant types of IncF plasmids, F2:A-:B-, carrying rmtB-qepA, and F33:A-:B-, carrying the rmtB-bla(CTX-M-9) group genes (and especially bla(CTX-M-65)), shared restriction patterns within each incompatibility group.
authors.affiliation: College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, People's Republic of China.
authors.forename: Yuting
authors.initials: Y
authors.lastname: Deng
authors.forename: Liangying
authors.initials: L
authors.lastname: He
authors.forename: Sheng
authors.initials: S
authors.lastname: Chen
authors.forename: Hongqing
authors.initials: H
authors.lastname: Zheng
authors.forename: Zhenling
authors.initials: Z
authors.lastname: Zeng
authors.forename: Yahong
authors.initials: Y
authors.lastname: Liu
authors.forename: Yan
authors.initials: Y
authors.lastname: Sun
authors.forename: Junying
authors.initials: J
authors.lastname: Ma
authors.forename: Zhangliu
authors.initials: Z
authors.lastname: Chen
authors.forename: Jian-Hua
authors.initials: JH
authors.lastname: Liu
mesh_terms: D000617:Aminoglycosides / Q000494:pharmacology; D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001426:Bacterial Proteins / Q000235:genetics; D002415:Cats; D002681:China; D004285:Dogs; D024901:Drug Resistance, Multiple, Bacterial; D004755:Enterobacteriaceae / Q000187:drug effects / Q000235:genetics* / Q000302:isolation & purification; D029968:Escherichia coli Proteins / Q000235:genetics*; D022761:Gene Transfer, Horizontal; D008780:Methyltransferases / Q000235:genetics*; D008826:Microbial Sensitivity Tests; D008969:Molecular Sequence Data; D057805:Pets / Q000382:microbiology*; D010957:Plasmids / Q000235:genetics*; D012336:RNA, Ribosomal, 16S / Q000235:genetics; D001618:beta-Lactamases / Q000235:genetics*
chemical_list: D000617:Aminoglycosides; D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; D029968:Escherichia coli Proteins; C524438:QepA protein, E coli; D012336:RNA, Ribosomal, 16S; D008780:Methyltransferases; C540682:RmtB protein, E coli; C412613:CTX-M-9 protein, E coli; D001618:beta-Lactamases