title: Histopathological changes in gill, liver and kidney of neotropical fish Colossoma macropomum exposed to paraquat at different temperatures.
abstract: This work focused on the histological alterations in gill, liver and kidney of fish Colossoma macropomum exposed to different temperatures (18°C, 29°C, 35°C) with 10mg/L of herbicide Paraquat (PQ), during 21 days. The fish exhibited histopathological changes in these tissues; the most important alteration in gills was telangiectasis. Liver showed debris accumulation inside cytoplasm hepatocytes, karyolysis, karyohesis and a decrease in the size of sinusoids. Hyperplasia of melanomacrophagic centers (MMC) and an increase in basophils were observed in kidney. The lesion inducing by PQ and the damage in tissue depended of temperature exposure fish. The severity of lesions clearly differed among organs with the liver showing the most extensive damages followed in order by the kidney and gills. In PQ/18°C group it was observed the changes in the pattern of lesions, with kidney showing higher damage followed gills and liver.
authors.affiliation: Departamento de Bioanálisis, Escuela de Ciencias, Universidad de Oriente, Núcleo de Sucre, Cumaná, Estado Sucre, Venezuela. raquelugove@yahoo.com
authors.forename: Raquel
authors.initials: R
authors.lastname: Salazar-Lugo
authors.forename: Claunis
authors.initials: C
authors.lastname: Mata
authors.forename: Aridays
authors.initials: A
authors.lastname: Oliveros
authors.forename: Luz Marina
authors.initials: LM
authors.lastname: Rojas
authors.forename: Mairin
authors.initials: M
authors.lastname: Lemus
authors.forename: Evelin
authors.initials: E
authors.lastname: Rojas-Villarroel
mesh_terms: D000818:Animals; D017756:Aquaculture; D001491:Basophils / Q000473:pathology; D060126:Characidae / Q000502:physiology*; D004784:Environmental Monitoring; D005880:Gills / Q000473:pathology*; D006540:Herbicides / Q000633:toxicity*; D007668:Kidney / Q000473:pathology*; D008099:Liver / Q000473:pathology*; D010269:Paraquat / Q000633:toxicity*; D013684:Telangiectasis / Q000139:chemically induced / Q000473:pathology; D013696:Temperature; D014687:Venezuela
chemical_list: D006540:Herbicides; D010269:Paraquat