title: Structure of Golgi transport proteins.
abstract: The function of the Golgi has long been recognized to critically depend on vesicular transport from, to, and within its cisternae, involving constant membrane fission and fusion. These processes are mediated by Arf GTPases and coat proteins, and Rabs, tethers and SNARE proteins, respectively. In this article, we describe structural studies of Golgi coats and tethers and their interactions with SNAREs and GTPases as well as insights regarding membrane traffic processes that these have provided.
authors.affiliation: Department of Cell Biology, Yale University School of Medicine, New Haven, Connecticut 06520, USA.
authors.forename: Daniel
authors.initials: D
authors.lastname: Kümmel
authors.forename: Karin M
authors.initials: KM
authors.lastname: Reinisch
mesh_terms: D022163:Clathrin-Coated Vesicles / Q000737:chemistry / Q000378:metabolism / Q000502:physiology; D005656:Fungal Proteins / Q000737:chemistry / Q000378:metabolism / Q000502:physiology; D006056:Golgi Apparatus / Q000378:metabolism*; D006801:Humans; D008565:Membrane Proteins / Q000737:chemistry* / Q000378:metabolism / Q000502:physiology; D008954:Models, Biological; D017434:Protein Structure, Tertiary; D021381:Protein Transport; D033921:Vesicular Transport Proteins / Q000737:chemistry / Q000378:metabolism / Q000502:physiology
chemical_list: D005656:Fungal Proteins; D008565:Membrane Proteins; D033921:Vesicular Transport Proteins