title: mTOR inhibitors in the treatment of subependymal giant-cell astrocytomas associated with tuberous sclerosis.
authors.forename: Ricardo J
authors.initials: RJ
authors.lastname: Komotar
authors.forename: Robert M
authors.initials: RM
authors.lastname: Starke
authors.forename: E Sander
authors.initials: ES
authors.lastname: Connolly
authors.forename: Michael B
authors.initials: MB
authors.lastname: Sisti
mesh_terms: D000818:Animals; D001254:Astrocytoma / Q000150:complications / Q000188:drug therapy* / Q000378:metabolism; D001932:Brain Neoplasms / Q000150:complications / Q000188:drug therapy* / Q000378:metabolism; D000068338:Everolimus; D006801:Humans; D020123:Sirolimus / Q000031:analogs & derivatives / Q000494:pharmacology / Q000627:therapeutic use; D058570:TOR Serine-Threonine Kinases / Q000037:antagonists & inhibitors* / Q000378:metabolism; D016896:Treatment Outcome; D014402:Tuberous Sclerosis / Q000150:complications / Q000188:drug therapy* / Q000378:metabolism
chemical_list: D000068338:Everolimus; C546842:MTOR protein, human; D058570:TOR Serine-Threonine Kinases; D020123:Sirolimus