title: A resettable dynamic microarray device.
abstract: This paper describes a simple reusable device that hydrodynamically traps a large number of beads in an array. Guiding pillars allow us to release the trapped beads by simply reversing the flow direction. The trap and reset operations are extremely simple, robust and highly efficient. We analyzed the path of the beads in a microchannel with pillars to optimize the design of the device. We succeeded in arraying hundreds of 100 μm microbeads, subsequently released them in a few minutes, and demonstrated multiple experiments with a single device.
authors.affiliation: Center for International Research on Micronano Mechatronics-CIRMM, Institute of Industrial Science-IIS, The University of Tokyo, Bunkyo, Japan.
authors.forename: Kosuke
authors.initials: K
authors.lastname: Iwai
authors.forename: Wei-Heong
authors.initials: WH
authors.lastname: Tan
authors.forename: Hirotaka
authors.initials: H
authors.lastname: Ishihara
authors.forename: Shoji
authors.initials: S
authors.lastname: Takeuchi
mesh_terms: D002469:Cell Separation / Q000295:instrumentation; D055252:Cell-Derived Microparticles / Q000737:chemistry; D004867:Equipment Design; D056656:Lab-On-A-Chip Devices; D046228:Microarray Analysis; D046210:Microfluidic Analytical Techniques / Q000295:instrumentation* / Q000379:methods*; D008863:Microspheres