title: Finding cases of Trichomonas vaginalis infection in England.
abstract: We describe the use of a new molecular assay for Trichomonas vaginalis (TV), the Gen-Probe Aptima TV (ATV) in female attendees at community clinics, a genitourinary (GU) medicine clinic and a prison GU medicine service. Positivity rates at community clinics and GU medicine were 0/382 (0%) and 3/358 (0.8%, 95% confidence interval [CI] 0-1.7%), respectively. Positivity was significantly higher, 29/269 (10.8%, 95% CI 7.1-14.5%), odds ratio (OR) 14.3 (4.11 < OR < 59.55), in those tested at the prison. A questionnaire survey of English GU medicine clinics and data from the UK Health Protection Agency (HPA) for England both demonstrated the large variation in case rates by region and testing methods employed. Higher rates were seen in women, in prison GU medicine services and in London GU medicine clinics. The ATV assay is now CE-marked (Conformité Européenne) and so a larger prospective study of its potential application is warranted.
authors.affiliation: East Cheshire NHS Trust, Macclesfield District General Hospital, Macclesfield, UK. drmmahto@aol.com
authors.forename: M
authors.initials: M
authors.lastname: Mahto
authors.forename: J
authors.initials: J
authors.lastname: Evans-Jones
authors.forename: S
authors.initials: S
authors.lastname: Zia
authors.forename: T I
authors.initials: TI
authors.lastname: Robinson
authors.forename: M M
authors.initials: MM
authors.lastname: Rothburn
authors.forename: H
authors.initials: H
authors.lastname: Mallinson
mesh_terms: D000328:Adult; D000554:Ambulatory Care Facilities / Q000706:statistics & numerical data; D018563:Disease Notification; D004739:England / Q000453:epidemiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D021141:Nucleic Acid Amplification Techniques; D016017:Odds Ratio; D011330:Prisons / Q000706:statistics & numerical data; D011446:Prospective Studies; D011635:Public Health Administration; D011933:Reagent Kits, Diagnostic; D011795:Surveys and Questionnaires; D014245:Trichomonas Infections / Q000175:diagnosis / Q000453:epidemiology*; D014246:Trichomonas vaginalis / Q000302:isolation & purification*
chemical_list: D011933:Reagent Kits, Diagnostic