title: The University of Kansas High-Throughput Screening Laboratory. Part II: enabling collaborative drug-discovery partnerships through cutting-edge screening technology.
abstract: The University of Kansas High-Throughput Screening (KU HTS) core is a state-of-the-art drug-discovery facility with an entrepreneurial open-service policy, which provides centralized resources supporting public- and private-sector research initiatives. The KU HTS core was established in 2002 at the University of Kansas with support from an NIH grant and the state of Kansas. It collaborates with investigators from national and international academic, nonprofit and pharmaceutical organizations in executing HTS-ready assay development and screening of chemical libraries for target validation, probe selection, hit identification and lead optimization. This is part two of a contribution from the KU HTS laboratory.
authors.affiliation: High-Throughput Screening Core Facility, Structural Biology Center, University of Kansas, Lawrence, KS 66047, USA.
authors.forename: Peter R
authors.initials: PR
authors.lastname: McDonald
authors.forename: Anuradha
authors.initials: A
authors.lastname: Roy
authors.forename: Rathnam
authors.initials: R
authors.lastname: Chaguturu
mesh_terms: D003299:Cooperative Behavior; D055808:Drug Discovery / Q000379:methods*; D057166:High-Throughput Screening Assays; D006801:Humans; D007615:Kansas; D010330:Patents as Topic; D054852:Small Molecule Libraries / Q000378:metabolism; D013678:Technology, Pharmaceutical / Q000379:methods*; D014495:Universities
chemical_list: D054852:Small Molecule Libraries