title: Recombinant factor VIIa use in refractory ulcer bleeding in uremic patient.
abstract: Peptic ulcer bleeding is thought to be a major cause of bleeding in patients with end-stage renal disease and is more complicated in uremic patients. We described a 41-year-old man with end-stage renal disease who underwent hemodialysis with refractory ulcer bleeding, failure to all traditional peptic ulcer treatments, and correction of uremic component, who has been successfully treated by using recombinant factor VIIa. There have been few case reports in dealing refractory upper gastrointestinal bleeding in uremic patients in the literature; and in this case report, we demonstrates that recombinant factor VIIa could be used as a rescue therapy in these high–surgical risk patients when medical therapy fails.
authors.affiliation: Department of Emergency Medicine, National Taiwan University Hospital, Taipei, Taiwan.
authors.forename: An-Yi
authors.initials: AY
authors.lastname: Wang
authors.forename: Ang
authors.initials: A
authors.lastname: Yuan
authors.forename: Chien-Hua
authors.initials: CH
authors.lastname: Huang
authors.forename: Wei-Tien
authors.initials: WT
authors.lastname: Chang
authors.forename: Po-Chin
authors.initials: PC
authors.lastname: Liang
authors.forename: Tzu-Hsin
authors.initials: TH
authors.lastname: Lin
authors.forename: Shyr-Chyr
authors.initials: SC
authors.lastname: Chen
mesh_terms: D000328:Adult; D004381:Duodenal Ulcer / Q000150:complications* / Q000000981:diagnostic imaging; D004386:Duodenum / Q000000981:diagnostic imaging; D015942:Factor VIIa / Q000627:therapeutic use*; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications; D008297:Male; D010438:Peptic Ulcer Hemorrhage / Q000150:complications / Q000000981:diagnostic imaging / Q000188:drug therapy*; D011994:Recombinant Proteins / Q000627:therapeutic use; D014057:Tomography, X-Ray Computed
chemical_list: D011994:Recombinant Proteins; C103587:recombinant FVIIa; D015942:Factor VIIa