title: Radiation-induced moyamoya disease after childhood astrocytoma.
abstract: Adjunctive radiation treatment of childhood intracranial neoplasms of grade II or higher creates a risk of subsequent vasculopathy. A 28-year-old male presented with a Glasgow Coma Scale 12 after acute collapse and hemiparesis with an intraparenchymal haematoma. Emergent craniotomy, histopathology and subsequent imaging confirmed the cause as radiation-induced moyamoya disease, subsequent to treatment for a grade 2 astrocytoma 24 years previously. He had been lost to follow-up after normal serial imaging performed up to 10 years after his initial diagnosis. Long term surveillance imaging may be of benefit in identifying treatable vascular anomalies.
authors.affiliation: Department of Neurosurgery, 7th Floor, Gold Coast Hospital, 108 Nerang Street, Southport, Queensland 4215, Australia. ben_manion@yahoo.com
authors.forename: Ben
authors.initials: B
authors.lastname: Manion
authors.forename: Wen-Shan
authors.initials: WS
authors.lastname: Sung
mesh_terms: D000328:Adult; D001254:Astrocytoma / Q000532:radiotherapy*; D001932:Brain Neoplasms / Q000532:radiotherapy*; D006801:Humans; D008297:Male; D009072:Moyamoya Disease / Q000175:diagnosis* / Q000209:etiology; D011832:Radiation Injuries / Q000175:diagnosis* / Q000209:etiology