title: Recurrence of erythema induratum of Bazin in a patient under chemotherapy for breast cancer.
abstract: Erythema induratum of Bazin (EIB) is a chronic nodular eruption occurring on the lower legs of young and middleaged women which is considered the most common tuberculid. A 54-year-old woman, in treatment with chemotherapy for breast cancer, presented subcutaneous erythematous plaques and nodules on the lower limbs. She had been diagnosed with EIB 3 years earlier and diagnostic work-up showed at that time signs suggestive of latent tuberculosis. The suspect of a recurrent form of EIB was confirmed by histopathological examination. A peculiar feature of our report consists in the recurrence of EIB, which is regarded as a hyperergic response against M. tuberculosis antigens, in a patient who was receiving chemotherapy with well-known immunosuppressive effects.
authors.affiliation: 2nd Dermatology Clinic, University of Bari, Policlinico, Bari, Italy. g.vena@dermatologia.uniba.it
authors.forename: Gino A
authors.initials: GA
authors.lastname: Vena
authors.forename: Doriana
authors.initials: D
authors.lastname: Apruzzi
authors.forename: Michelangelo
authors.initials: M
authors.lastname: Vestita
authors.forename: Maria
authors.initials: M
authors.lastname: Panaro
authors.forename: Simona
authors.initials: S
authors.lastname: Carpagnano
authors.forename: Ruggero
authors.initials: R
authors.lastname: Filannino
authors.forename: Nicoletta
authors.initials: N
authors.lastname: Cassano
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use; D001943:Breast Neoplasms / Q000188:drug therapy* / Q000382:microbiology*; D004891:Erythema Induratum / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009169:Mycobacterium tuberculosis / Q000187:drug effects / Q000472:pathogenicity
chemical_list: D000970:Antineoplastic Agents