title: [Study on purification of strictosamide from Nauclea officinalis by macroporous resin].
abstract: OBJECTIVE
  To study on the purification of strictosamide from Nauclea officinalis by macroporous resin to provide reference for production.
  
  
  METHODS
  The best macroporous resin was selected among 10 kinds of resins according to adsorption and desorption of the static adsorption experiments. The adsorption quantity, elution volume of water, concentration and elution volume of alcohol were determined according to the single factor experiment.
  
  
  RESULTS
  HPD400 was the best resin, and the best adsorption quantity was 20.23 mg x g(-1), the elution volume of water and 30% alcohol was 6 BV, and the elution volume of 70% alcohol was 4 BV.
  
  
  CONCLUSIONS
  This technology is simple, feasible, and it can provide reference for the industrialized production.
authors.affiliation: Jiangsu Zeukov Pharmaceutical S&T Inc., Nanjing 210017, China.
authors.forename: Zhaoqing
authors.initials: Z
authors.lastname: Meng
authors.forename: Gang
authors.initials: G
authors.lastname: Ding
authors.forename: Yujie
authors.initials: Y
authors.lastname: Liu
authors.forename: Jia
authors.initials: J
authors.lastname: Xu
authors.forename: Wenjun
authors.initials: W
authors.lastname: Liu
authors.forename: Wei
authors.initials: W
authors.lastname: Xiao
mesh_terms: D000327:Adsorption; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification; D000431:Ethanol / Q000737:chemistry; D012117:Resins, Synthetic / Q000737:chemistry*; D019666:Rubiaceae / Q000737:chemistry*; D013678:Technology, Pharmaceutical / Q000379:methods*; D014748:Vinca Alkaloids / Q000737:chemistry / Q000302:isolation & purification*
chemical_list: D004365:Drugs, Chinese Herbal; D012117:Resins, Synthetic; D014748:Vinca Alkaloids; C539462:strictosamide; D000431:Ethanol