title: [Nourishing-yin effect and mechanism of different parts of Cornu Elaphuri Davidiani in rats].
abstract: OBJECTIVE
  To investigate nourishing-yin effect and mechanism of different parts of Cornu Elaphuri Davidiani in rats.
  
  
  METHODS
  The model of yin asthenia rats was built by thy roxine. The substance metabolism, pain threshold, hormone levels and biochemical indicators in serum were measured.
  
  
  RESULTS
  The ethanol extract of Cornu Elaphuri Davidiani could regulate the substance metabolism and raise the pain threshold in yin asthenia model rats. Furthermore, it could regulate the hormone levels, biochemical indicators in serum and it could improvte the antioxidant ability.
  
  
  CONCLUSIONS
  The ethanol extract of Cornu Elaphuri Davidiani showed significant nourishing-yin effect in rats and the possible mechanism is correlated with regulating the neuroendocrine network.
authors.affiliation: Jiangsu Provincial Institute of Traditional Chinese Medicine, Nanjing 210028, China. pengyunru@126.com
authors.forename: Yun-ru
authors.initials: YR
authors.lastname: Peng
authors.forename: Da-wei
authors.initials: DW
authors.lastname: Qian
authors.forename: Jin-ao
authors.initials: JA
authors.lastname: Duan
authors.forename: Yu-hua
authors.initials: YH
authors.lastname: Ding
mesh_terms: D000324:Adrenocorticotropic Hormone / Q000097:blood; D000818:Animals; D000999:Antlers; D003670:Deer; D004195:Disease Models, Animal; D004958:Estradiol / Q000097:blood; D000431:Ethanol / Q000737:chemistry; D005260:Female; D006980:Hyperthyroidism / Q000097:blood / Q000139:chemically induced / Q000188:drug therapy*; D007376:Interleukin-2 / Q000097:blood; D008297:Male; D008419:Materia Medica / Q000008:administration & dosage / Q000494:pharmacology*; D008516:Medicine, Chinese Traditional; D017288:Pain Threshold / Q000187:drug effects; D011897:Random Allocation; D051381:Rats; D017207:Rats, Sprague-Dawley; D013482:Superoxide Dismutase / Q000097:blood; D013739:Testosterone / Q000097:blood; D013974:Thyroxine / Q000009:adverse effects; D016710:Yin Deficiency / Q000097:blood / Q000139:chemically induced / Q000188:drug therapy*
chemical_list: D007376:Interleukin-2; D008419:Materia Medica; D000431:Ethanol; D013739:Testosterone; D004958:Estradiol; D000324:Adrenocorticotropic Hormone; D013482:Superoxide Dismutase; D013974:Thyroxine