title: [Neonatal seizures revealing incontinentia pigmenti].
abstract: Incontinentia pigmenti (IP) is a rare affection inherited as X-linked dominant disease. It is usually lethal in male infants. IP can affect ectodermal tissues such as the skin, teeth, eyes, bones, and the central nervous system. Skin lesions occur mostly during the neonatal period and are characterized by a classic progression in 4 stages leading to hyperpigmentation. We report on the case of a female neonate presenting on the 3rd day of life with seizures without obvious cause, in which the diagnosis of IP was made 1 week later when skin lesions appeared.
authors.affiliation: Service de néonatologie, CHU Farhat-Hached, Sousse, Tunisie. soniamerchaoui@yahoo.fr
authors.forename: S
authors.initials: S
authors.lastname: Nouri-Merchaoui
authors.forename: N
authors.initials: N
authors.lastname: Mahdhaoui
authors.forename: J
authors.initials: J
authors.lastname: Methlouthi
authors.forename: R
authors.initials: R
authors.lastname: Zakhama
authors.forename: H
authors.initials: H
authors.lastname: Seboui
mesh_terms: D000927:Anticonvulsants / Q000627:therapeutic use; D003241:Consanguinity; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007184:Incontinentia Pigmenti / Q000175:diagnosis* / Q000235:genetics* / Q000473:pathology; D007231:Infant, Newborn; D010634:Phenobarbital / Q000627:therapeutic use; D012307:Risk Factors; D012640:Seizures / Q000188:drug therapy / Q000235:genetics*; D012867:Skin / Q000473:pathology*; D014071:Tooth Abnormalities / Q000473:pathology*; D016896:Treatment Outcome
chemical_list: D000927:Anticonvulsants; D010634:Phenobarbital