title: Biphenyl and biphenyl ether quinolizidine N-oxide alkaloids from Lagerstroemia indica L.
abstract: Four new biphenyl and biphenyl ether quinolizidine N-oxide alkaloids, 5- EPI-dihydrolyfoline N-oxide (1), decamine N-oxide (2), lagerstroemine N-oxide (3), and lagerine N-oxide (4), were isolated from the aerial parts of Lagerstroemia indica, and their structures were established by extensive spectroscopic studies. In addition, the inhibitory effects of isolated compounds on rat lens aldose reductase (RLAR) were examined.
authors.affiliation: College of Pharmacy, Chungnam National University, Daejeon, Republic of Korea.
authors.forename: IkSoo
authors.initials: I
authors.lastname: Lee
authors.forename: UiJoung
authors.initials: U
authors.lastname: Youn
authors.forename: HongJin
authors.initials: H
authors.lastname: Kim
authors.forename: ByungSun
authors.initials: B
authors.lastname: Min
authors.forename: Jin Sook
authors.initials: JS
authors.lastname: Kim
authors.forename: KiHwan
authors.initials: K
authors.lastname: Bae
mesh_terms: D000449:Aldehyde Reductase / Q000187:drug effects; D000470:Alkaloids / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D000818:Animals; D001713:Biphenyl Compounds / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D005591:Chemical Fractionation; D003497:Cyclic N-Oxides / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D004791:Enzyme Inhibitors / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D004987:Ethers / Q000737:chemistry; D031563:Lagerstroemia / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D035261:Plant Components, Aerial / Q000737:chemistry; D054837:Quinolizidines / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D051381:Rats; D017207:Rats, Sprague-Dawley
chemical_list: D000449:Aldehyde Reductase; D000470:Alkaloids; D001713:Biphenyl Compounds; D003497:Cyclic N-Oxides; D004791:Enzyme Inhibitors; D004987:Ethers; D054837:Quinolizidines; C571317:5-epi-dihydrolyfoline N-oxide; C571312:decamine N-oxide; C571319:lagerine N-oxide; C571318:lagerstroemine N-oxide; C010574:biphenyl