title: Asynchronous osteoradionecrosis of the mandible treated with sequential fibula osteoseptocutaneous flaps: a report of two cases.
abstract: Osteroradionecrosis of the mandible is one of the most serious complications of radiotherapy in head and neck cancer. Once osteoradionecrosis of the mandible has been established, conservative therapy is often useless. Two cases of asynchronous bilateral osteoradionecrosis of the mandible are presented. In both cases, successful reconstruction was performed with 2 free fibula osteoseptocutaneous flap transfers from both legs. We believe that adequate debridement, with removal of dead or hypovascular bone and surrounding soft tissue, followed by vascularized composite bone grafts, is the key for a successful outcome. In our cases, the oral function after 2 reconstructive surgeries with the fibula osteoseptocutaneous flap was acceptable. Furthermore, the patient could walk without difficulty.
authors.affiliation: Department of Plastic Surgery, Faculty of Medicine, Oita University, Hasumi, Oita, Japan. fumi@med.oita-u.ac.jp
authors.forename: Fumiaki
authors.initials: F
authors.lastname: Shimizu
authors.forename: Aiko
authors.initials: A
authors.lastname: Kato
authors.forename: Hiroko
authors.initials: H
authors.lastname: Taneda
authors.forename: Daisuke
authors.initials: D
authors.lastname: Masuda
authors.forename: Seiichi
authors.initials: S
authors.lastname: Sato
authors.forename: Miyuki
authors.initials: M
authors.lastname: Uehara
authors.forename: Kaho
authors.initials: K
authors.lastname: Matsuda
authors.forename: Kenji
authors.initials: K
authors.lastname: Kawano
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Takahashi
authors.forename: Kenji
authors.initials: K
authors.lastname: Yamaguchi
authors.forename: Sakuhei
authors.initials: S
authors.lastname: Fujiwara
mesh_terms: D000368:Aged; D005360:Fibula / Q000637:transplantation; D006801:Humans; D008297:Male; D008336:Mandibular Diseases / Q000601:surgery*; D010025:Osteoradionecrosis / Q000601:surgery*; D016038:Skin Transplantation; D013524:Surgical Flaps