title: Building the DREAM interactome.
abstract: DREAM/calsenilin/KChIP3 is a calcium binding protein of the neuronal calcium sensor superfamily. DREAM interacts with DRE (downstream regulatory element) sites in the DNA to regulate transcription and with many proteins to exert specialized functions in different subcellular compartments. Work from different laboratories has identified a growing list of interacting proteins that constitutes the DREAM interactome. The knowledge of these interactions has greatly contributed to the understanding of the various physiological functions of DREAM.
authors.affiliation: Department of Molecular and Cellular Biology, National Center of Biotechnology, Consejo Superior Investigaciones Cientificas, Madrid, Spain.
authors.forename: Marcos
authors.initials: M
authors.lastname: Rivas
authors.forename: Diego
authors.initials: D
authors.lastname: Villar
authors.forename: Paz
authors.initials: P
authors.lastname: González
authors.forename: Xosé M
authors.initials: XM
authors.lastname: Dopazo
authors.forename: Britt
authors.initials: B
authors.lastname: Mellstrom
authors.forename: José R
authors.initials: JR
authors.lastname: Naranjo
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D004247:DNA / Q000378:metabolism; D005786:Gene Expression Regulation; D006801:Humans; D051605:Kv Channel-Interacting Proteins / Q000235:genetics / Q000378:metabolism*; D008969:Molecular Sequence Data; D011485:Protein Binding; D025941:Protein Interaction Mapping / Q000379:methods*; D016415:Sequence Alignment; D013961:Thyroid Gland / Q000502:physiology; D020798:Two-Hybrid System Techniques
chemical_list: D051605:Kv Channel-Interacting Proteins; D004247:DNA