title: Research and technology in neurocritical care.
abstract: The daily practice of neurointensivists focuses on the recognition of subtle changes in the neurological examination, interactions between the brain and systemic derangements, and brain physiology. Common alterations such as fever, hyperglycemia, and hypotension have different consequences in patients with brain insults compared with patients of general medical illness. Various technologies have become available or are currently being developed. The session on "research and technology" of the first neurocritical care research conference held in Houston in September of 2009 was devoted to the discussion of the current status, and the research role of state-of-the art technologies in neurocritical patients including multi-modality neuromonitoring, biomarkers, neuroimaging, and "omics" research (proteomix, genomics, and metabolomics). We have summarized the topics discussed in this session. We have provided a brief overview of the current status of these technologies, and put forward recommendations for future research applications in the field of neurocritical care.
authors.affiliation: Department of Neurology, Stanford University, Palo Alto, CA, USA. cwijman@stanford.edu
authors.forename: C A C
authors.initials: CA
authors.lastname: Wijman
authors.forename: S M
authors.initials: SM
authors.lastname: Smirnakis
authors.forename: P
authors.initials: P
authors.lastname: Vespa
authors.forename: K
authors.initials: K
authors.lastname: Szigeti
authors.forename: W C
authors.initials: WC
authors.lastname: Ziai
authors.forename: M M
authors.initials: MM
authors.lastname: Ning
authors.forename: J
authors.initials: J
authors.lastname: Rosand
authors.forename: D F
authors.initials: DF
authors.lastname: Hanley
authors.forename: R
authors.initials: R
authors.lastname: Geocadin
authors.forename: C
authors.initials: C
authors.lastname: Hall
authors.forename: P D
authors.initials: PD
authors.lastname: Le Roux
authors.forename: J I
authors.initials: JI
authors.lastname: Suarez
authors.forename: O O
authors.initials: OO
authors.lastname: Zaidat
mesh_terms: D020811:Biomedical Technology / Q000379:methods* / Q000639:trends*; D003422:Critical Care / Q000379:methods / Q000639:trends; D023281:Genomics / Q000379:methods / Q000639:trends; D006801:Humans; D055432:Metabolomics / Q000379:methods / Q000639:trends; D009422:Nervous System Diseases / Q000235:genetics / Q000378:metabolism / Q000628:therapy*; D040901:Proteomics / Q000379:methods / Q000639:trends; D012107:Research Design / Q000639:trends