title: Nanotechniques in proteomics: protein microarrays and novel detection platforms.
abstract: The field of proteomics has undergone rapid advancements over the last decade and protein microarrays have emerged as a promising technological platform for the challenging tasks of studying complex proteomes. Researchers have gone beyond traditional techniques and approached promising disciplines like nanotechnology to satisfy the growing demands of studying proteins in high-throughput format. Applications of nanotechnology in proteomics came from the need to detect low-abundant proteins in complex mixtures for sensitive, real-time and multiplexed detection platform. The scope of this article is to outline the current status and key technological advances of nanotechniques in protein microarrays.
authors.affiliation: Centro de Investigación del Cáncer/IBMCC (USAL/CSIC), Departamento de Medicina and Servicio General de Citometría, University of Salamanca, 37007 Salamanca, Spain.
authors.forename: María
authors.initials: M
authors.lastname: Gonzalez-Gonzalez
authors.forename: Ricardo
authors.initials: R
authors.lastname: Jara-Acevedo
authors.forename: Sergio
authors.initials: S
authors.lastname: Matarraz
authors.forename: María
authors.initials: M
authors.lastname: Jara-Acevedo
authors.forename: Sara
authors.initials: S
authors.lastname: Paradinas
authors.forename: J M
authors.initials: JM
authors.lastname: Sayagües
authors.forename: Alberto
authors.initials: A
authors.lastname: Orfao
authors.forename: Manuel
authors.initials: M
authors.lastname: Fuentes
mesh_terms: D006801:Humans; D036103:Nanotechnology / Q000379:methods*; D040081:Protein Array Analysis; D040901:Proteomics / Q000379:methods*