title: Discontinued drugs 2010: rheumatology, allergy and dermatology, pulmonary.
abstract: This is the annual perspective paper on the discontinued drugs in the field of pulmonary disease allergy, rheumatology, and dermatology. It is part of series of papers discussing drugs dropped from clinical development in the previous year and presented according to therapeutic indication. Specifically, this paper presents the four rheumatology and dermatology, four pulmonary and three allergy drugs discontinued in 2010. Information for this perspective was derived from a search of the Pharmaprojects database for drugs discontinued after reaching Phase I - III clinical trials.
authors.affiliation: Gr.T.Popa University of Medicine and Pharmacy Iasi, Pulmonary Disease University Hospital, Pulmonary Disease Department, 30 Dr I Cihac Str, 700115 Iasi, Romania. sabina.antonela.antoniu@pneum.umfiasi.ro
authors.forename: Sabina A
authors.initials: SA
authors.lastname: Antoniu
mesh_terms: D000630:Aminopterin / Q000031:analogs & derivatives / Q000627:therapeutic use; D018926:Anti-Allergic Agents / Q000627:therapeutic use; D000890:Anti-Infective Agents / Q000627:therapeutic use; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D000911:Antibodies, Monoclonal / Q000627:therapeutic use; D000982:Antipruritics / Q000627:therapeutic use; D018501:Antirheumatic Agents / Q000627:therapeutic use; D001993:Bronchodilator Agents / Q000627:therapeutic use; D015507:Drugs, Investigational / Q000627:therapeutic use; D006801:Humans; D051550:I-kappa B Kinase / Q000037:antagonists & inhibitors; D007155:Immunologic Factors / Q000627:therapeutic use; D008228:Lymphoma, Non-Hodgkin / Q000188:drug therapy
chemical_list: C512248:4'-methylene-5,8,10-trideazaaminopterin; D018926:Anti-Allergic Agents; D000890:Anti-Infective Agents; D000893:Anti-Inflammatory Agents; D000911:Antibodies, Monoclonal; D000982:Antipruritics; D018501:Antirheumatic Agents; D001993:Bronchodilator Agents; D015507:Drugs, Investigational; D007155:Immunologic Factors; D051550:I-kappa B Kinase; D000630:Aminopterin; C437823:galiximab