title: Influence of metal alloy and the profile of coronary stents in patients with multivessel coronary disease.
abstract: BACKGROUND
  In Brazil, despite the recommendations of the Brazilian Society of Hemodynamics and Interventional Cardiology, the National Health System has not yet approved the use of drug-eluting stents. In percutaneous coronary interventions performed in the public and part of the private health care system, bare metal stents are used as the only option. Therefore, new information on bare metal stents is of great importance. The primary endpoint was to evaluate the influence of the alloy and the profile of coronary stents on late loss and restenosis rates 6 months after implantation in patients with multivessel coronary disease.
  
  
  METHODS
  Single center, randomized and prospective study comparison of cobalt-chromium versus stainless steel stent implantation in 187 patients with multivessel coronary disease. At least one cobalt-chromium and one stainless steel stent were implanted per patient.
  
  
  RESULTS
  Mean age of patients was 59.5 + 10.1 years with a prevalence of males (66.3%) and patients with acute coronary syndrome (56%). Baseline clinical characteristics were similar with hypertension in 146 (78%), dyslipidemia in 85 (45.5%) and diabetes in 68 (36.4%). Two hundred and twenty-nine cobalt-chromium and 284 stainless steel stents were implanted. Angiographic variables showed no statistically significant difference. Angiographic follow-up to 6 months after implantation showed similar late loss and restenosis rates.
  
  
  CONCLUSIONS
  The use of two different alloys, stainless steel and cobalt-chrome stents, in the same patient and in the same vessel produced similar 6-month restenosis and late loss rates.
authors.affiliation: Hospital Stella Maris, Guarulhos, SP, Brazil.
authors.forename: Luciano Maurício de
authors.initials: LM
authors.lastname: Abreu Filho
authors.forename: Antonio Artur da Cruz
authors.initials: AA
authors.lastname: Forte
authors.forename: Marcos Kiyoshi
authors.initials: MK
authors.lastname: Sumita
authors.forename: Desidério
authors.initials: D
authors.lastname: Favarato
authors.forename: George Cesar Ximenes
authors.initials: GC
authors.lastname: Meireles
mesh_terms: D000368:Aged; D019917:Blood Vessel Prosthesis Implantation / Q000379:methods; D001938:Brazil; D002858:Chromium Alloys / Q000627:therapeutic use*; D003324:Coronary Artery Disease / Q000601:surgery*; D023903:Coronary Restenosis / Q000517:prevention & control*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012307:Risk Factors; D013193:Stainless Steel; D015607:Stents; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D002858:Chromium Alloys; D013193:Stainless Steel