title: Determination of epichlorohydrin and 1,3-dichloro-2-propanol in synthesis of cationic etherifying reagent by headspace gas chromatography.
abstract: This study demonstrates a headspace gas chromatographic(HS-GC) technique for the determination of residual epichlorohydrin (ECH) and generated 1,3-dichloro-2-propanol (DCP) in synthesis process of 3-chloro-2-hydroxypropyltrimethylammonium chloride (CHTAC). By a weight-based sampling method, coupled with significant dilution in 15.8% sodium sulfate and 0.1% silver nitrate mixed solution rapidly, the sample for HS-GC analysis is prepared. Based on the reaction stoichiometry, the conversion (R) of CHTAC during the synthesis process can be calculated from sampling weight and GC peak area. The results showed that the method has a good measurement precision (RSD<2.5%) and accuracy (recovery=101-104%) for the quantification of both ECH and DCP in the process samples. The present method is simple and accurate, which can be used for the efficient determination of the CHTAC conversion in the synthesis research.
authors.affiliation: State Key Laboratory of Pulp and Paper Engineering, South China University of Technology, 510640, China.
authors.forename: Zheng-Yi
authors.initials: ZY
authors.lastname: Tao
authors.forename: Xin-Sheng
authors.initials: XS
authors.lastname: Chai
authors.forename: Shu-Bin
authors.initials: SB
authors.lastname: Wu
mesh_terms: D002849:Chromatography, Gas / Q000379:methods*; D004811:Epichlorohydrin / Q000032:analysis* / Q000737:chemistry; D020005:Propanols / Q000138:chemical synthesis* / Q000737:chemistry; D000644:Quaternary Ammonium Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012835:Silver Nitrate / Q000737:chemistry; D013431:Sulfates / Q000737:chemistry; D000517:alpha-Chlorohydrin / Q000031:analogs & derivatives* / Q000032:analysis / Q000737:chemistry
chemical_list: D020005:Propanols; D000644:Quaternary Ammonium Compounds; D013431:Sulfates; D004811:Epichlorohydrin; C033489:1,3-dichloro-2-propanol; C012036:sodium sulfate; D012835:Silver Nitrate; D000517:alpha-Chlorohydrin; C496948:(3-chloro-2-hydroxypropyl)trimethylammonium chloride