title: Stem cell engineering: limitation, alternatives, and insight.
abstract: The 21st century will see improvements in the quality of human life. The development of new therapeutic technologies will prevent prevalent diseases and enable recovery from currently incurable diseases. The development of cell and tissue replacement therapies using stem cells and their progenitors will accelerate the development of causative treatments. The effort expended thus far in developing cell therapies has revealed many technical limitations. Thus, we must explore conceptual changes in the feasibility of stem cell therapy. This paper introduces the current limitations to stem cell engineering and ways to overcome these limitations, which will provide new insight into their clinical application.
authors.affiliation: WCU Biomodulation and Department of Agricultural Biotechnology, Seoul National University, Seoul, Korea. limjm@snu.ac.kr
authors.forename: Jeong Mook
authors.initials: JM
authors.lastname: Lim
authors.forename: Myungook
authors.initials: M
authors.lastname: Lee
authors.forename: Eun Ju
authors.initials: EJ
authors.lastname: Lee
authors.forename: Seung Pyo
authors.initials: SP
authors.lastname: Gong
authors.forename: Seung Tae
authors.initials: ST
authors.lastname: Lee
mesh_terms: D000818:Animals; D006801:Humans; D033581:Stem Cell Transplantation / Q000379:methods / Q000639:trends*; D013234:Stem Cells / Q000166:cytology* / Q000378:metabolism; D023822:Tissue Engineering / Q000379:methods