title: Life-space mobility is associated with frequency of hospitalization in adults with cystic fibrosis.
abstract: OBJECTIVE
  The Life-Space Assessment can be used to measure a patient's level of mobility. This study evaluated the relationship between life-space mobility and frequency of hospitalization in the previous year and other clinical markers of health among adults with cystic fibrosis (CF).
  
  
  METHODS
  The Life-Space Assessment was administered to ambulatory adults with CF in clinic or by telephone. Life-space mobility was correlated with the most recent forced expiratory volume in one second as a percent of the predicted value (FEV(1) % predicted), body mass index (BMI) and number of hospitalizations in the previous year.
  
  
  RESULTS
  Forty-eight subjects completed the Life-Space Assessment. Subjects had a life-space score of 88 ± 26, FEV(1) % predicted of 66% ± 26% and BMI of 22.5 ± 3.3. There was a statistically significant negative linear correlation between the number of times a subject was hospitalized in the previous year and life-space mobility (P = 0.001, R(2) = 0.20). This association was independent of FEV(1) % predicted and BMI.
  
  
  CONCLUSIONS
  The life-space mobility score is associated with frequency of hospitalization in adults with CF. A prospective study should be undertaken to assess the ability of the Life-Space Assessment to predict hospitalization and other outcomes in adults with CF.
authors.affiliation: Emory Cystic Fibrosis Center, Atlanta, GA, USA.
authors.forename: Eric Raphael
authors.initials: ER
authors.lastname: Gottlieb
authors.forename: Elisabeth Christine
authors.initials: EC
authors.lastname: Smith
authors.forename: Linda Lucetta
authors.initials: LL
authors.lastname: Wolfenden
authors.forename: Richard Mark
authors.initials: RM
authors.lastname: Allman
authors.forename: Vin
authors.initials: V
authors.lastname: Tangpricha
mesh_terms: D000328:Adult; D015992:Body Mass Index; D003550:Cystic Fibrosis / Q000503:physiopathology* / Q000628:therapy; D005260:Female; D005541:Forced Expiratory Volume; D006760:Hospitalization; D006801:Humans; D008297:Male; D011788:Quality of Life; D011795:Surveys and Questionnaires; D016138:Walking