title: Gram-negative groin sepsis treated with covered stents and systemic antibiotics.
abstract: Prosthetic graft infections are hazardous conditions. Those due to Gram-negative bacteria are particularly serious. When Gram-negative microorganisms are present, entire graft excision is recommended, with revascularization if needed, preferably with autogenous tissues or with prosthetic grafts via non-infected planes if autogenous options are not available. We herein report the case of a diabetic man with critical limb ischemia, who after lower-extremity revascularization with a prosthetic graft, developed an early graft infection due to Gram-negative and fungal organisms, and who was successfully treated with a covered stent placed across grossly infected tissues. A discussion on the pertinent literature is also offered.
authors.affiliation: University of Arizona Health Science Center, Tucson, AZ, USA. luis@luisleonmd.com
authors.forename: Luis R
authors.initials: LR
authors.lastname: Leon
authors.forename: Janice
authors.initials: J
authors.lastname: Thai
authors.forename: John P
authors.initials: JP
authors.lastname: Pacanowski
mesh_terms: D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D001807:Blood Vessel Prosthesis / Q000009:adverse effects*; D019917:Blood Vessel Prosthesis Implantation / Q000009:adverse effects* / Q000295:instrumentation; D020878:Device Removal; D006090:Gram-Negative Bacteria / Q000302:isolation & purification*; D006119:Groin / Q000098:blood supply*; D006801:Humans; D008297:Male; D008875:Middle Aged; D016459:Prosthesis-Related Infections / Q000000981:diagnostic imaging / Q000382:microbiology / Q000628:therapy; D012086:Reoperation; D018805:Sepsis / Q000000981:diagnostic imaging / Q000382:microbiology / Q000628:therapy; D015607:Stents; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D014945:Wound Healing
chemical_list: D000900:Anti-Bacterial Agents