title: [HHV-6 infection and its clinical significance].
abstract: Human herpes virus 6 (HHV-6) is a common virus, known as the causative agent of exanthema subitum. In addition, the virus is known for its tropism for the central nervous system and as the causative agent of encephalitides. HHV-6 produces a lifetime latency and may be reactivated during immunosuppression therapy for instance in organ transplantation patients. In recent years, new laboratory methods have improved the diagnostics of HHV-6 infections and enabled the study of the clinical significance of the virus. Although specific drugs effective against the virus are available, their clinical use is not established.
authors.affiliation: HUSLAB, virologian osasto ja Helsingen yliopisto, PL 400, 00029 HUS.
authors.forename: Irmeli
authors.initials: I
authors.lastname: Lautenschlager
authors.forename: Raisa
authors.initials: R
authors.lastname: Loginov
mesh_terms: D004660:Encephalitis / Q000821:virology; D005077:Exanthema Subitum / Q000821:virology; D015654:Herpesvirus 6, Human; D006801:Humans; D019349:Roseolovirus Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000821:virology*