title: Updated Brazilian STR allele frequency data using over 100,000 individuals: an analysis of CSF1PO, D3S1358, D5S818, D7S820, D8S1179, D13S317, D16S539, D18S51, D21S11, FGA, Penta D, Penta E, TH01, TPOX and vWA loci.
abstract: The Brazilian population is one of the most heterogeneous populations of the world, formed mainly by an admixture of European, African and Native American populations. Brazil is the fifth largest country in the world (8,511,960 km(2)), being divided into five geographical regions. This study provides population genetic data of up to 137,161 unrelated individuals representing the entire Brazilian territory. Allelic frequencies and other population data analysis are reported for the 15 autosomal STR loci included in the PowerPlex®16 kit (Promega Corporation, Madison, WI, USA). In order to guarantee that individuals were not related, we have considered only F1 data from couples undergoing paternity testing. The number of individuals genotyped for each locus was: CSF1PO (113,526); D3S1358 (135,133); D5S818 (135,181); D7S820 (137,136); D8S1179 (134,211); D13S317 (137,161); D16S539 (136,942); D18S51 (136,739); D21S11 (130,014); FGA (135,839); Penta D (110,333); Penta E (128,055); TH01 (112,695); TPOX (123,102); vWA (127,415). Allele sizes ranged from 1 to 48.2. Statistic parameters (PD, PIC and Ho; considering values ≥0.75) suggest that markers D13S317, D16S539, D18S51, D21S11, D7S820, D8S1179, Penta D, Penta E, TH01, FGA and vWA were more informative for genetic identification purposes in the Brazilian population.
authors.affiliation: Núcleo de Genética Humana e Molecular, Departamento de Ciências Biológicas, Centro de Ciências Humanas e Naturais, Universidade Federal do Espírito Santo, Av. Marechal Campos 1468, Campus de Maruípe, CEP 29040-090 Vitória, ES, Brazil.
authors.forename: Vitor Rezende da Costa
authors.initials: VR
authors.lastname: Aguiar
authors.forename: Eldamária de Vargas
authors.initials: Ede V
authors.lastname: Wolfgramm
authors.forename: Frederico Scott Varella
authors.initials: FS
authors.lastname: Malta
authors.forename: Adriana Gonçalves
authors.initials: AG
authors.lastname: Bosque
authors.forename: Amanda de Castro
authors.initials: Ade C
authors.lastname: Mafia
authors.forename: Vanessa Cristina de Oliveira
authors.initials: VC
authors.lastname: Almeida
authors.forename: Fabiola de Andrade
authors.initials: Fde A
authors.lastname: Caxito
authors.forename: Victor Cavalcanti
authors.initials: VC
authors.lastname: Pardini
authors.forename: Alessandro Clayton Souza
authors.initials: AC
authors.lastname: Ferreira
authors.forename: Iúri Drumond
authors.initials: ID
authors.lastname: Louro
mesh_terms: D001938:Brazil; D016172:DNA Fingerprinting / Q000379:methods; D019075:Electrophoresis, Capillary; D005787:Gene Frequency; D056426:Genetic Loci; D005828:Genetics, Population; D005838:Genotype; D006801:Humans; D018895:Microsatellite Repeats; D016133:Polymerase Chain Reaction