title: Qualitative variation of anti-diabetic compounds in different tarragon (Artemisia dracunculus L.) cytotypes.
abstract: Ethanolic extracts of diploid Artemisia dracunculus L. (wild tarragon) from populations in the U.S., and polyploid tarragon from a variety of sources, were screened for the anti-diabetic compounds davidigenin; sakuranetin; 2',4'-dihydroxy-4-methoxydihydrochalcone; 4,5-di-O-caffeoylquinic acid; 5-O-caffeoylquinic acid and 6-demethoxycapillarisin using LC-MS. Only decaploid plants contained all six target compounds and were the only plants that contained davidigenin and 2,4-dihydroxy-4-methoxydihydrochalcone. These results exhibit the importance of germplasm selection and provenance when studying plants for medicinal activity. Relying only on the "right species" for consistent medicinal activities may not be sufficient, as intraspecific variation may be highly significant.
authors.affiliation: Rutgers University, School of Environmental and Biological Sciences, Department of Plant Biology and Pathology, Cook Campus, New Brunswick, NJ 08901-8520, USA. eisenman@temple.edu
authors.forename: Sasha W
authors.initials: SW
authors.lastname: Eisenman
authors.forename: Alexander
authors.initials: A
authors.lastname: Poulev
authors.forename: Lena
authors.initials: L
authors.lastname: Struwe
authors.forename: Ilya
authors.initials: I
authors.lastname: Raskin
authors.forename: David M
authors.initials: DM
authors.lastname: Ribnicky
mesh_terms: D019306:Artemisia / Q000737:chemistry* / Q000235:genetics; D014644:Genetic Variation; D007004:Hypoglycemic Agents / Q000032:analysis*; D015394:Molecular Structure; D010936:Plant Extracts / Q000737:chemistry*; D011123:Polyploidy
chemical_list: D007004:Hypoglycemic Agents; D010936:Plant Extracts