title: Bilateral multiple inflammatory myofibroblastic tumors of the lung successfully treated with corticosteroids.
abstract: Inflammatory myofibroblastic tumor (IMT) is a rare tumorous lesion that presents as a solitary nodule. Complete surgical resection is the standard treatment. However, due to its rarity, the optimal therapeutic strategy for multiple IMTs has not been defined. A 32-year-old man was referred to our hospital for evaluation of multiple pulmonary nodules. On computed tomography (CT) scan of the chest, there were a 3.0 × 1.7 cm mass with heterogeneous enhancement in the left upper lobe and multiple small nodules bilaterally. We performed wedge resection of the mass, and histopathology revealed IMT. He was treated with oral corticosteroids. The clinical and radiologic responses were so excellent that a CT scan showed complete resolution 1 month after the initiation of corticosteroid therapy. These observations suggest that corticosteroids may be the way to treat bilateral multiple IMT of the lung.
authors.affiliation: Department of Internal Medicine, Research Center for Pulmonary Disorders, Chonbuk National University Medical School, Jeonju, South Korea.
authors.forename: Min Hee
authors.initials: MH
authors.lastname: Lee
authors.forename: Heung Bum
authors.initials: HB
authors.lastname: Lee
authors.forename: Yong Chul
authors.initials: YC
authors.lastname: Lee
authors.forename: Yang Keun
authors.initials: YK
authors.lastname: Rhee
authors.forename: Eun Jung
authors.initials: EJ
authors.lastname: Lee
authors.forename: Myoung Ja
authors.initials: MJ
authors.lastname: Chung
authors.forename: Gong Yong
authors.initials: GY
authors.lastname: Jin
authors.forename: Eui Yong
authors.initials: EY
authors.lastname: Kweon
authors.forename: Seoung Ju
authors.initials: SJ
authors.lastname: Park
mesh_terms: D000328:Adult; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D006104:Granuloma, Plasma Cell / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D008297:Male; D055613:Multiple Pulmonary Nodules / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D009379:Neoplasms, Muscle Tissue / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D011241:Prednisone / Q000627:therapeutic use*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D000970:Antineoplastic Agents; D011241:Prednisone