title: A preclinical study of stem subsidence and graft incorporation after femoral impaction grafting using porous hydroxyapatite as a bone graft extender.
abstract: This preclinical in vivo screening study compared bone graft incorporation and stem subsidence in cemented hemiarthroplasty after femoral impaction bone grafting with either morselized allograft bone (n = 5, control group) or a 1:1 mix of allograft and porous hydroxyapatite ceramics (HA) granules (n = 5, HA group). At 14 weeks, there was excellent bone graft incorporation by bone, and the stems were well fixed in both groups. The median subsidence at the cement-bone interface, measured using radiostereometric analysis, was 0.14 and 0.93 mm in the control and HA groups, respectively. The comparable histologic results between groups and good stem fixation in this study support the conduct of a larger scale investigation of the use of porous HA in femoral impaction bone grafting at revision hip arthroplasty.
authors.affiliation: The Department of Orthopaedics and Trauma, Royal Adelaide Hospital, Adelaide, South Australia, Australia.
authors.forename: Donald W
authors.initials: DW
authors.lastname: Howie
authors.forename: Margaret A
authors.initials: MA
authors.lastname: McGee
authors.forename: Stuart A
authors.initials: SA
authors.lastname: Callary
authors.forename: Angelo
authors.initials: A
authors.lastname: Carbone
authors.forename: Roumen B
authors.initials: RB
authors.lastname: Stamenkov
authors.forename: Warrick J
authors.initials: WJ
authors.lastname: Bruce
authors.forename: David M
authors.initials: DM
authors.lastname: Findlay
mesh_terms: D000818:Animals; D018786:Bone Substitutes; D016025:Bone Transplantation; D017886:Durapatite; D005269:Femur / Q000473:pathology / Q000601:surgery*; D006622:Hip Prosthesis; D016348:Osseointegration; D016062:Porosity; D059869:Radiostereometric Analysis; D012756:Sheep
chemical_list: D018786:Bone Substitutes; D017886:Durapatite