title: The RNA profile of porcine parvovirus 4, a boca-like virus, is unique among the parvoviruses.
abstract: PPV4 transcribes its genome from a single promoter, and the RNAs are generated via alternate splicing coupled with alternate polyadenylation, a strategy similar to that of the bocaviruses; however, several differences were detected. The PPV4 ORF1 codes for four NS proteins, while the bocavirus ORF1 codes for 1-3 NS proteins. Whereas the VP1/VP2 capsid proteins of bocavirus are encoded by a single RNA, VP1 and VP2 of PPV4 are encoded by two separate RNAs. While ORF3 of PPV4 encodes two NP proteins, ORF3 of bocavirus codes for only one NP polypeptide. Taken together, PPV4 is unique among the parvoviruses.
authors.affiliation: Virus and Prion Research Unit, National Animal Disease Center, USDA, Agricultural Research Service, P.O. Box 70, Ames, IA 50010, USA. andrew.cheung@ars.usda.gov
authors.forename: Andrew K
authors.initials: AK
authors.lastname: Cheung
authors.forename: Jin-Xue
authors.initials: JX
authors.lastname: Long
authors.forename: Lv
authors.initials: L
authors.lastname: Huang
authors.forename: Shi-Shan
authors.initials: SS
authors.lastname: Yuan
mesh_terms: D000818:Animals; D002460:Cell Line; D016679:Genome, Viral; D008969:Molecular Sequence Data; D016366:Open Reading Frames; D010322:Parvoviridae Infections / Q000662:veterinary* / Q000821:virology; D028323:Parvovirus, Porcine / Q000235:genetics* / Q000302:isolation & purification; D012367:RNA, Viral / Q000235:genetics*; D013552:Swine; D013553:Swine Diseases / Q000821:virology*; D014764:Viral Proteins / Q000235:genetics
chemical_list: D012367:RNA, Viral; D014764:Viral Proteins