title: Metallothioneins and heat shock proteins 70 in marine mussels as sensors of environmental pollution in Northern Adriatic Sea.
abstract: In an attempt to assess the intensity of environmental pollution in industrial zones of Kvarnerian Bay in Northern Adriatic Sea and the reactivity of Mytilus galloprovincialis to these changes, in this study we estimated the concentration of heavy metals at four locations in both sea-sediment and in the mussels. Further we tried to correlate these changes with seasonal variations in environmental temperature, pH and salinity, as well as with the expression of metallothioneins (MTs) and heat shock proteins (HSPs) in the digestive tract of the mussels. Sampling in vivo was performed monthly, during the year 2008, while under the laboratory conditions the reactivity of acclimated mussels were tested to increasing concentrations of CdCl(2) and to thermal stress. The data have shown that the induction of MTs and HSP isoforms of the 70-kDa size class were highly affected by model agents treatment including contamination of sea-sediment by Pb, Hg and Cd, implying that these stress proteins might be power biomarkers of marine pollution.
authors.affiliation: Teaching Institute of Public Health, Primorsko-Goranska County, Medical Faculty, University of Rijeka, Rijeka, Croatia.
authors.forename: Vladimir
authors.initials: V
authors.lastname: Mićović
authors.forename: Aleksandar
authors.initials: A
authors.lastname: Bulog
authors.forename: Natalia
authors.initials: N
authors.lastname: Kučić
authors.forename: Hrvoje
authors.initials: H
authors.lastname: Jakovac
authors.forename: Biserka
authors.initials: B
authors.lastname: Radošević-Stašić