title: Krukenberg tumor of gastric origin in pregnancy with dismal outcome.
abstract: Krukenberg tumors are mostly found as metastatic signet-ring cell adenomucinous carcinomas in young, premenopausal women. They are bilateral in 80% of the cases, and thus can be expected in pregnancy. A 31-year-old female was diagnosed by explorative laparotomy at 27 weeks of gestation with a Krukenberg tumor due to bilateral adnexal masses and a large amount of ascites. At surgery cesarean section with total abdominal hysterectomy, bilateral salpingo-oophorectomy, total omentectomy and pelvic lymphadenectomy was performed. The neonate died 24 hours later due to prematurity and respiratory distress syndrome. The primary site of the cancer was detected metachronously two months after surgery and postoperative chemotherapy, as stomach adenomucinous carcinoma. In spite of surgery and postoperative multiagent chemotherapy, the patient died six months from the diagnosis of Krukenberg.
authors.affiliation: Institute of Gynecology and Obstetrics, University of Belgrade, Clinical Centre of Serbia, Belgrade, Serbia. jelence_01@open.telecom.rs
authors.forename: J
authors.initials: J
authors.lastname: Stojnic
authors.forename: A
authors.initials: A
authors.lastname: Stefanovic
authors.forename: K
authors.initials: K
authors.lastname: Jeremic
authors.forename: S
authors.initials: S
authors.lastname: Kadija
authors.forename: M
authors.initials: M
authors.lastname: Jeftovic
authors.forename: J
authors.initials: J
authors.lastname: Jeremic
mesh_terms: D000328:Adult; D018279:Carcinoma, Signet Ring Cell / Q000473:pathology* / Q000601:surgery; D002585:Cesarean Section; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007044:Hysterectomy; D007725:Krukenberg Tumor / Q000473:pathology* / Q000601:surgery; D010051:Ovarian Neoplasms / Q000473:pathology* / Q000601:surgery; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000473:pathology* / Q000601:surgery; D013274:Stomach Neoplasms / Q000473:pathology* / Q000601:surgery