title: Marine diterpene glycosides.
abstract: Marine diterpene glycosides (MDGs) respresent a small but highly significant group of the much larger class of marine diterpenes. The three well-studied examples of MDGs are eleutherobins, pseudopterosins and fuscosides, all of which exhibit extremely promising biological activity. The eleutherobins are potent anti-mitotic agents, and the pseudopterosins and fuscosides are potent anti-inflammatory agents. This review discusses the structures and biological activities of these compounds, as well as their biosynthesis and synthesis.
authors.affiliation: Department of Chemistry, University of Prince Edward Island, Charlottetown, PEI, Canada.
authors.forename: Fabrice
authors.initials: F
authors.lastname: Berrué
authors.forename: Malcolm W B
authors.initials: MW
authors.lastname: McCulloch
authors.forename: Russell G
authors.initials: RG
authors.lastname: Kerr
mesh_terms: D000818:Animals; D037421:Anthozoa / Q000737:chemistry / Q000378:metabolism; D059001:Aquatic Organisms / Q000737:chemistry* / Q000378:metabolism; D004224:Diterpenes / Q000737:chemistry* / Q000378:metabolism; D006027:Glycosides / Q000096:biosynthesis / Q000737:chemistry*
chemical_list: D004224:Diterpenes; D006027:Glycosides; C109551:eleutherobin