title: Longitudinal characterization of Acinetobacter baumannii-calcoaceticus complex, Klebsiella pneumoniae, and methicillin-resistant Staphylococcus aureus colonizing and infecting combat casualties.
abstract: Drug-resistant Acinetobacter baumannii-calcoaceticus complex, Klebsiella pneumoniae, and methicillin-resistant Staphylococcus aureus colonize and infect combat casualties from Iraq and Afghanistan. We retrospectively evaluated relatedness, by pulsed-field gel electrophoresis and antibiotic susceptibility testing, of isolates colonizing and infecting casualties over 2 years. Colonizing organisms were unrelated to isolates producing later infection in up to 27% of cases; most isolates underwent change in antibiotic susceptibilities. The same is true for serial infecting isolates recovered during hospitalization.
authors.affiliation: Brooke Army Medical Center, Fort Sam Houston, TX, USA.
authors.forename: Rebekah A
authors.initials: RA
authors.lastname: Sensenig
authors.forename: Clinton K
authors.initials: CK
authors.lastname: Murray
authors.forename: Katrin
authors.initials: K
authors.lastname: Mende
authors.forename: Steven E
authors.initials: SE
authors.lastname: Wolf
authors.forename: Kevin K
authors.initials: KK
authors.lastname: Chung
authors.forename: Duane R
authors.initials: DR
authors.lastname: Hospenthal
authors.forename: Heather C
authors.initials: HC
authors.lastname: Yun
mesh_terms: D040981:Acinetobacter baumannii / Q000235:genetics* / Q000302:isolation & purification; D016954:Acinetobacter calcoaceticus / Q000235:genetics* / Q000302:isolation & purification; D055826:Afghan Campaign 2001-; D015373:Bacterial Typing Techniques; D003428:Cross Infection / Q000188:drug therapy / Q000382:microbiology*; D024901:Drug Resistance, Multiple, Bacterial / Q000235:genetics*; D016521:Electrophoresis, Gel, Pulsed-Field; D006772:Hospitals, Military; D006801:Humans; D054542:Iraq War, 2003-2011; D007711:Klebsiella pneumoniae / Q000235:genetics* / Q000302:isolation & purification; D008137:Longitudinal Studies; D055624:Methicillin-Resistant Staphylococcus aureus / Q000235:genetics* / Q000302:isolation & purification; D008826:Microbial Sensitivity Tests; D008889:Military Personnel; D012189:Retrospective Studies; D014481:United States; D014947:Wounds and Injuries / Q000188:drug therapy / Q000382:microbiology*