title: Hypertensive crisis due to contrast-enhanced computed tomography in a patient with malignant pheochromocytoma.
abstract: A 63-year-old man underwent computed tomography (CT) using intravenous low-osmolar iodine contrast medium (LOCM) 6 days after undergoing high-dose (131)I-MIBG therapy for metastatic pheochromocytoma. Immediately after the CT examination, his blood pressure increased to 260/160 mmHg (from 179/101 mmHg before the examination). Phentolamine mesilate was administered, and the blood pressure rapidly went back to normal. Although hypertensive crisis after administration of LOCM is rare, this case suggests that high-dose (131)IMIBG therapy may be a risk factor for hypertensive crisis after administration of intravenous LOCM.
authors.affiliation: Department of Diagnostic Radiology and Nuclear Medicine, Gunma University Hospital, 3-39-15 Showa-machi, Maebashi, Gunma 371-8511, Japan. be_shappy@yahoo.co.jp
authors.forename: Sachiko
authors.initials: S
authors.lastname: Nakano
authors.forename: Yoshito
authors.initials: Y
authors.lastname: Tsushima
authors.forename: Ayako
authors.initials: A
authors.lastname: Taketomi-Takahashi
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Higuchi
authors.forename: Makoto
authors.initials: M
authors.lastname: Amanuma
authors.forename: Noboru
authors.initials: N
authors.lastname: Oriuchi
authors.forename: Keigo
authors.initials: K
authors.lastname: Endo
mesh_terms: D019797:3-Iodobenzylguanidine / Q000627:therapeutic use; D000310:Adrenal Gland Neoplasms / Q000000981:diagnostic imaging* / Q000532:radiotherapy; D003287:Contrast Media / Q000009:adverse effects*; D006801:Humans; D020343:Hypertensive Encephalopathy / Q000139:chemically induced*; D007479:Iopamidol / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D010673:Pheochromocytoma / Q000000981:diagnostic imaging* / Q000532:radiotherapy; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals / Q000627:therapeutic use*; D014057:Tomography, X-Ray Computed / Q000009:adverse effects*
chemical_list: D003287:Contrast Media; D019275:Radiopharmaceuticals; D019797:3-Iodobenzylguanidine; D007479:Iopamidol