title: The role of adhesion energy in controlling cell-cell contacts.
abstract: Recent advances in microscopy techniques and biophysical measurements have provided novel insight into the molecular, cellular and biophysical basis of cell adhesion. However, comparably little is known about a core element of cell-cell adhesion--the energy of adhesion at the cell-cell contact. In this review, we discuss approaches to understand the nature and regulation of adhesion energy, and propose strategies to determine adhesion energy between cells in vitro and in vivo.
authors.affiliation: Institute of Science and Technology Austria, Am Campus 1, 3400 Klosterneuburg, Austria.
authors.forename: Jean-Léon
authors.initials: JL
authors.lastname: Maître
authors.forename: Carl-Philipp
authors.initials: CP
authors.lastname: Heisenberg
mesh_terms: D000818:Animals; D015820:Cadherins / Q000378:metabolism; D051177:Catenins / Q000378:metabolism; D002448:Cell Adhesion; D002465:Cell Movement; D003599:Cytoskeleton; D004734:Energy Metabolism; D006801:Humans
chemical_list: D015820:Cadherins; D051177:Catenins