title: Continuous flow hydrogenation using polysilane-supported palladium/alumina hybrid catalysts.
abstract: Continuous flow systems for hydrogenation using polysilane-supported palladium/alumina (Pd/(PSi-Al(2)O(3))) hybrid catalysts were developed. Our original Pd/(PSi-Al(2)O(3)) catalysts were used successfully in these systems and the hydrogenation of unsaturated C-C bonds and a nitro group, deprotection of a carbobenzyloxy (Cbz) group, and a dehalogenation reaction proceeded smoothly. The catalyst retained high activity for at least 8 h under neat conditions.
authors.affiliation: Department of Chemistry, School of Science and Graduate School of Pharmaceutical Sciences, The University of Tokyo, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.
authors.forename: Hidekazu
authors.initials: H
authors.lastname: Oyamada
authors.forename: Takeshi
authors.initials: T
authors.lastname: Naito
authors.forename: Shū
authors.initials: S
authors.lastname: Kobayashi