title: [Characteristics of the pineal gland and thymus relationship in aging].
abstract: The review presents the interference between thymus and pineal gland during their involution. The research data of thymus peptides influence on pineal gland and pineal peptides on thymus are summarized. Analysis of these data showed that pineal peptides (Epithalamin, Epitalon) had more effective geroprotective effect on thymus involution in comparison with geroprotective effect of thymic peptides (Thymalin, Thymogen) on involution of pineal gland. The key mechanisms of pineal peptides effect on thymus dystrophy is immunoendocrine cooperation, which is realized as transcription's activation of various proteins.
authors.forename: N S
authors.initials: NS
authors.lastname: Lin'kova
authors.forename: V O
authors.initials: VO
authors.lastname: Poliakova
authors.forename: I M
authors.initials: IM
authors.lastname: Kvetnoĭ
authors.forename: A V
authors.initials: AV
authors.lastname: Trofimov
authors.forename: N N
authors.initials: NN
authors.lastname: Sevost'ianova
mesh_terms: D000375:Aging / Q000187:drug effects / Q000378:metabolism / Q000502:physiology*; D000818:Animals; D004151:Dipeptides / Q000378:metabolism / Q000494:pharmacology / Q000502:physiology; D006801:Humans; D015213:Neuroimmunomodulation / Q000187:drug effects / Q000502:physiology; D009842:Oligopeptides / Q000378:metabolism / Q000494:pharmacology / Q000502:physiology; D010455:Peptides / Q000378:metabolism / Q000494:pharmacology / Q000502:physiology; D010870:Pineal Gland / Q000502:physiology*; D013950:Thymus Gland / Q000378:metabolism / Q000502:physiology*; D013951:Thymus Hormones / Q000378:metabolism / Q000494:pharmacology / Q000502:physiology
chemical_list: D004151:Dipeptides; D009842:Oligopeptides; D010455:Peptides; D013951:Thymus Hormones; C060736:thymogen; C027437:epithalamin; C032805:thymalin; C421253:alanyl-glutamyl-aspartyl-glycine