title: [Study on diagnosis of chronic schistosomiasis japonicum with rSj26-Sj32 fusion protein].
abstract: OBJECTIVE
  To study whether rSj26-Sj32 fusion protein can be used for diagnosis of chronic schistosomiasis japonicum.
  
  
  METHODS
  ELISA, Dot-ELISA and dipstick were performed to detect the IgG in the sera of patients with chronic schistosomiasis japonicum using the antigens of rSj26-Sj32 fusion protein and SjAWA. The control sera were taken from health donors and the patients with clonorchiasis sinensis, paragonimiasis westermani, alveolar echinococcosis and cystic echinococcosis.
  
  
  RESULTS
  The sensitivity of the three methods was 95.00%, 92.50% and 92.50% respectively, whereas the specificity of the three methods was 97.67%, 95.35% and 97.67%, respectively.
  
  
  CONCLUSIONS
  The rSj26-Sj32 fusion protein has therapeutic potential for immunodiagnosis of chronic schistosomiasis japonicum.
authors.affiliation: Institute of Infectious and Parasitic Diseases, the First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China.
authors.forename: Shi-fei
authors.initials: SF
authors.lastname: Cai
authors.forename: Wen-gui
authors.initials: WG
authors.lastname: Li
authors.forename: Min
authors.initials: M
authors.lastname: Wang
mesh_terms: D000818:Animals; D002908:Chronic Disease; D004797:Enzyme-Linked Immunosorbent Assay; D004926:Escherichia coli / Q000235:genetics / Q000378:metabolism; D015964:Gene Expression Regulation, Bacterial; D005822:Genetic Vectors / Q000235:genetics; D015801:Helminth Proteins / Q000235:genetics / Q000378:metabolism; D006801:Humans; D011993:Recombinant Fusion Proteins / Q000235:genetics / Q000378:metabolism; D012549:Schistosoma japonicum / Q000235:genetics; D012554:Schistosomiasis japonica / Q000175:diagnosis*
chemical_list: D015801:Helminth Proteins; D011993:Recombinant Fusion Proteins