title: Palladium(II)-catalyzed cycloisomerization of functionalized 1,5-hexadienes.
abstract: Scope and limitations of the Pd(II)-catalyzed cycloisomerization of functionalized 1,5-hexadienes have been studied. In situ NMR experiments indicate a challenging competition between various reaction pathways. A careful balance between substrate structure, nature of the precatalyst, and reaction conditions was required to gain access to a useful building block for sesquiterpene total synthesis.
authors.affiliation: Fakultät Chemie, Technische Universität Dortmund, 44227 Dortmund, Germany.
authors.forename: Björn
authors.initials: B
authors.lastname: Nelson
authors.forename: Wolf
authors.initials: W
authors.lastname: Hiller
authors.forename: Annett
authors.initials: A
authors.lastname: Pollex
authors.forename: Martin
authors.initials: M
authors.lastname: Hiersemann
mesh_terms: D000466:Alkadienes / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000466:Alkadienes; C545783:1,5-hexadiene; D010165:Palladium