title: Medication use for chronic health conditions by pregnant women attending an Australian maternity hospital.
abstract: BACKGROUND
  Most women use medications at some stage in their pregnancy. Medication nonadherence during pregnancy could be detrimental to both mother and fetus.
  
  
  OBJECTIVE
  To study the extent and nature of the use of prescribed medications during pregnancy and factors associated with medication nonadherence.
  
  
  METHODS
  All women≥18 years presenting for their 36th week antenatal visit at the pregnancy clinic of a maternity hospital were invited to complete an anonymous questionnaire that contained 61 items, including the Morisky scale. Factors associated with nonadherence were identified in univariate analysis; factors with P<0.1 were further analysed in a binary logistic regression model.
  
  
  RESULTS
  The participants (n=819) had a mean age of 30.8±5.3 years. Most participants were born in Australia, lived with a partner, had university education, were nulliparous, carried one fetus and were nonsmokers. Of these participants, 322 (39.3%) reported a chronic health condition during pregnancy, the most common being asthma (104; 12.7%). Two hundred and seventeen (26.5%) were using prescribed medications, which included anti-anaemics (68; 8.3%), medicines for chronic airway conditions (64; 7.8%), vitamins and minerals (59; 7.2%) and anti-diabetics (43; 5.2%). Nonadherence was reported by 107 (59.1%) participants, mainly because of forgetting (79; 43.6%). Factors associated with nonadherence were having asthma (OR 0.26 (95% CI 0.095-0.72), P=0.009) and using nonprescription dietary minerals (0.30 (0.10-0.87), P=0.027).
  
  
  CONCLUSIONS
  Adherence to prescribed medicines during pregnancy is alarmingly low. Health professionals should be more proactive in promoting adherence and assisting women avoid potential fetal harm because of nonadherence.
authors.affiliation: Centre for Medicine Use and Safety, Department of Pharmacy Practice, Faculty of Pharmacy and Pharmaceutical Sciences, Monash University, and Pharmacy Department, The Royal Women's Hospital, Parkville, Victoria, Australia.
authors.forename: Emilia
authors.initials: E
authors.lastname: Sawicki
authors.forename: Kay
authors.initials: K
authors.lastname: Stewart
authors.forename: Swee
authors.initials: S
authors.lastname: Wong
authors.forename: Laura
authors.initials: L
authors.lastname: Leung
authors.forename: Eldho
authors.initials: E
authors.lastname: Paul
authors.forename: Johnson
authors.initials: J
authors.lastname: George
mesh_terms: D000293:Adolescent; D000328:Adult; D000740:Anemia / Q000188:drug therapy*; D001249:Asthma / Q000188:drug therapy*; D001315:Australia; D002908:Chronic Disease; D003430:Cross-Sectional Studies; D003920:Diabetes Mellitus / Q000188:drug therapy*; D005260:Female; D006771:Hospitals, Maternity; D006801:Humans; D008173:Lung Diseases, Obstructive / Q000188:drug therapy; D008875:Middle Aged; D004366:Nonprescription Drugs / Q000627:therapeutic use; D011247:Pregnancy; D055553:Prescription Drugs / Q000627:therapeutic use*; D011795:Surveys and Questionnaires; D014131:Trace Elements / Q000627:therapeutic use; D014815:Vitamins / Q000627:therapeutic use; D055815:Young Adult; D016903:Drug Monitoring
chemical_list: D004366:Nonprescription Drugs; D055553:Prescription Drugs; D014131:Trace Elements; D014815:Vitamins