title: Management of Hypertension among Patients with Coronary Heart Disease.
abstract: Evidence suggests that coronary heart disease (CHD) is the most common outcome of hypertension. Hypertension accelerates the development of atherosclerosis, and sustained elevation of blood pressure (BP) can destabilize vascular lesions and precipitate acute coronary events. Hypertension can cause myocardial ischemia in the absence of CHD. These cardiovascular risks attributed to hypertension can be reduced by optimal BP control. Although several antihypertensive agents exist, the choice of agent and the appropriate target BP for patients with CHD remain controversial. In this succinct paper, we examine the evidence and the mechanisms for the linkage between hypertension and CHD and we discuss the treatment options and the goals of therapy that are consistent with the report of the seventh Joint National Committee on the Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC 7) and American Heart Association scientific statement. We anticipate changes in the recommendations of the forthcoming JNC 8.
authors.affiliation: Brooklyn Health Disparities Center, Department of Medicine, SUNY Downstate Medical Center, Brooklyn, NY 11203, USA.
authors.forename: Oladipupo
authors.initials: O
authors.lastname: Olafiranye
authors.forename: Ferdinand
authors.initials: F
authors.lastname: Zizi
authors.forename: Perry
authors.initials: P
authors.lastname: Brimah
authors.forename: Girardin
authors.initials: G
authors.lastname: Jean-Louis
authors.forename: Amgad N
authors.initials: AN
authors.lastname: Makaryus
authors.forename: Samy
authors.initials: S
authors.lastname: McFarlane
authors.forename: Gbenga
authors.initials: G
authors.lastname: Ogedegbe