title: [Carcinosarcoma of the corpus uteri: potential of p53, PTEN and COX-2 expression for survival].
abstract: Clinico-morphological and immunohistochemical examinations were carried out in 46 patients with carcinocarcinoma of the corpus uteri to evaluate p53, PTEN and cyclooxygenase-2 (COX-2) expression in mesenchymal and epithelial cells of tumor. p53 expression in the epithelium and that of COX-2 in both compartments appeared to be unfavorable prognosticators of survival while that of PTEN is a lesser one in significance.
authors.forename: N V
authors.initials: NV
authors.lastname: Levitskaia
authors.forename: K M
authors.initials: KM
authors.lastname: Pozharisskiĭ
authors.forename: L N
authors.initials: LN
authors.lastname: Alekseeva
authors.forename: T V
authors.initials: TV
authors.lastname: Kharitonova
authors.forename: I V
authors.initials: IV
authors.lastname: Matrosova
authors.forename: I V
authors.initials: IV
authors.lastname: Poddubnaia
mesh_terms: D000328:Adult; D000368:Aged; D014408:Biomarkers, Tumor / Q000032:analysis*; D002296:Carcinosarcoma / Q000737:chemistry* / Q000401:mortality / Q000473:pathology*; D051546:Cyclooxygenase 2 / Q000032:analysis*; D005260:Female; D015972:Gene Expression Regulation, Neoplastic; D006801:Humans; D007150:Immunohistochemistry; D008875:Middle Aged; D051059:PTEN Phosphohydrolase / Q000032:analysis*; D011237:Predictive Value of Tests; D011379:Prognosis; D016019:Survival Analysis; D016159:Tumor Suppressor Protein p53 / Q000032:analysis*; D014594:Uterine Neoplasms / Q000737:chemistry* / Q000401:mortality / Q000473:pathology*
chemical_list: D014408:Biomarkers, Tumor; D016159:Tumor Suppressor Protein p53; D051546:Cyclooxygenase 2; C496540:PTGS2 protein, human; D051059:PTEN Phosphohydrolase; C494929:PTEN protein, human