title: Primary hypothyroidism presenting as pseudoacromegaly.
abstract: Pseudoacromegaly is a condition characterized by cutaneous manifestations of growth hormone excess but with normal growth hormone levels. This is described in patients with severe insulin resistance, pachydermoperiostitis, burnt out acromegaly and with intake of drugs like Minoxidil. Severe thyroid hormone deficiency rarely present with similar picture and the issue is further complicated in presence of pituitary hyperplasia. We report an unusual presentation of primary hypothyroidism with pseudoacromegaly and thyrotroph hyperplasia mimicking a pituitary macroadenoma. The thyrotroph hyperplasia resolved completely with levothyroxine therapy.
authors.affiliation: Department of Endocrinology, Command Hospital, Lucknow, UP, 226002, India. hariendo@rediffmail.com
authors.forename: K V S Hari
authors.initials: KV
authors.lastname: Kumar
authors.forename: Altamash
authors.initials: A
authors.lastname: Shaikh
authors.forename: Irfan
authors.initials: I
authors.lastname: Anwar
authors.forename: P
authors.initials: P
authors.lastname: Prusty
mesh_terms: D000172:Acromegaly / Q000175:diagnosis* / Q000378:metabolism; D000328:Adult; D006801:Humans; D007037:Hypothyroidism / Q000175:diagnosis* / Q000378:metabolism; D007333:Insulin Resistance; D008297:Male; D010902:Pituitary Gland / Q000473:pathology; D055815:Young Adult