title: [Study on chemical constituents from leaves of Tripterygium wilfordii].
abstract: In order to study the chemical constituents of the leaves of Tripterygium wilfordii and provide references for the bio-active study, we isolated nine compounds from the dried leaves of Tripterygium wilfordii. Their structures were determined by application of spectroscopic (NMR, MS) and chemical methods. These compounds were isolated and identified as (+)-lyoniresinol (1), (+)-isolariciresinol (2), burselignan (3), dibutyl phthalate (4), cyclo-(S-Pro-R-Phe) (5), cyclo-(S-Pro-R-Leu) (6), cyclo-(S-Pro-S-Ile) (7), 3-hydroxy-1-(4-hydroxy-3,5-dimethoxyphenyl)-1-propanone (8) and daucosterol (9). Compounds 1-3, 5-8 were isolated from this plant for the first time.
authors.affiliation: Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herb Medicine, Ministry of Education, Institute of Materia Medica, Peking Union Medical College Chinese Academy of Medical Sciences, Beijing 100050, China.
authors.forename: Xu
authors.initials: X
authors.lastname: Cao
authors.forename: Chuangjun
authors.initials: C
authors.lastname: Li
authors.forename: Jingzhi
authors.initials: J
authors.lastname: Yang
authors.forename: Baixing
authors.initials: B
authors.lastname: Wei
authors.forename: Yongming
authors.initials: Y
authors.lastname: Luo
authors.forename: Dongming
authors.initials: D
authors.lastname: Zhang
mesh_terms: D000840:Anisoles / Q000737:chemistry / Q000302:isolation & purification; D003993:Dibutyl Phthalate / Q000737:chemistry / Q000302:isolation & purification; D008031:Lignin / Q000737:chemistry / Q000302:isolation & purification; D008279:Magnetic Resonance Imaging / Q000379:methods; D013058:Mass Spectrometry / Q000379:methods; D009281:Naphthalenes / Q000737:chemistry / Q000302:isolation & purification; D009284:Naphthols / Q000737:chemistry / Q000302:isolation & purification; D010456:Peptides, Cyclic / Q000737:chemistry / Q000302:isolation & purification; D010936:Plant Extracts / Q000737:chemistry* / Q000302:isolation & purification*; D018515:Plant Leaves / Q000737:chemistry*; D012855:Sitosterols / Q000737:chemistry / Q000302:isolation & purification; D029757:Tripterygium / Q000737:chemistry*
chemical_list: D000840:Anisoles; D009281:Naphthalenes; D009284:Naphthols; D010456:Peptides, Cyclic; D010936:Plant Extracts; D012855:Sitosterols; C502379:lyoniresinol; D003993:Dibutyl Phthalate; C060284:isolariciresinol; D008031:Lignin; C011015:lyoniside