title: Clinical trial design in the neurocritical care unit.
abstract: Clinical trials provide a robust mechanism to advance science and change clinical practice across the widest possible spectrum. Fundamental in the Neurocritical Care Society's mission is to promote Quality Patient Care by identifying and implementing best medical practices for acute neurological disorders that are consistent with the current scientific knowledge. The next logical step will be to foster rapid growth of our scientific body of evidence, to establish and disseminate these best practices. In this manuscript, five invited experts were impaneled to address questions, identified by the conference organizing committee as fundamental issues for the design of clinical trials in the neurological intensive care unit setting.
authors.affiliation: University of Texas Southwestern, Dallas, TX, USA.
authors.forename: C E
authors.initials: CE
authors.lastname: Hall
authors.forename: M
authors.initials: M
authors.lastname: Mirski
authors.forename: Y Y
authors.initials: YY
authors.lastname: Palesch
authors.forename: M N
authors.initials: MN
authors.lastname: Diringer
authors.forename: A I
authors.initials: AI
authors.lastname: Qureshi
authors.forename: C S
authors.initials: CS
authors.lastname: Robertson
authors.forename: R
authors.initials: R
authors.lastname: Geocadin
authors.forename: C A C
authors.initials: CA
authors.lastname: Wijman
authors.forename: P D
authors.initials: PD
authors.lastname: Le Roux
authors.forename: Jose I
authors.initials: JI
authors.lastname: Suarez
mesh_terms: D002986:Clinical Trials as Topic / Q000191:economics / Q000379:methods / Q000592:standards; D003422:Critical Care / Q000379:methods*; D006801:Humans; D009422:Nervous System Diseases / Q000628:therapy*; D012107:Research Design / Q000592:standards*