title: [Pathological gambling induced by dopamine agonists].
abstract: Problems with impulse control and pathological gambling are known as possible side effects of dopaminergic therapy in patients with Parkinson's disease. We report 2 cases of pathological gambling induced by dopamine agonists in patients without Parkinson's disease. The first patient, a 46-year-old man, was treated with ropinirole for restless legs syndrome and had lost huge amounts of money in the context of internet-based poker game. Another 46-year-old male patient developed pathological gambling under treatment with cabergoline administered for prolactinoma. The two cases implicate pathological gambling as a possible consequence of dopaminergic treatment and support the increasing evidence regarding pathological gambling as an adverse drug reaction of dopaminergic treatment, also in patients who do not suffer from Parkinson's disease.
authors.affiliation: Klinik für Psychiatrie und Psychotherapie III, Universitätsklinikum Ulm. maximilian.gahr@uni-ulm.de
authors.forename: M
authors.initials: M
authors.lastname: Gahr
authors.forename: B J
authors.initials: BJ
authors.lastname: Connemann
authors.forename: C J
authors.initials: CJ
authors.lastname: Schönfeldt-Lecuona
mesh_terms: D000978:Antiparkinson Agents / Q000009:adverse effects* / Q000627:therapeutic use; D000077465:Cabergoline; D018491:Dopamine Agonists / Q000009:adverse effects* / Q000627:therapeutic use; D004873:Ergolines / Q000009:adverse effects* / Q000627:therapeutic use; D005715:Gambling / Q000139:chemically induced* / Q000523:psychology*; D006801:Humans; D007211:Indoles / Q000009:adverse effects* / Q000627:therapeutic use; D038801:International Classification of Diseases; D008297:Male; D008875:Middle Aged; D010911:Pituitary Neoplasms / Q000150:complications / Q000188:drug therapy; D015175:Prolactinoma / Q000150:complications / Q000188:drug therapy; D012148:Restless Legs Syndrome / Q000150:complications / Q000188:drug therapy
chemical_list: D000978:Antiparkinson Agents; D018491:Dopamine Agonists; D004873:Ergolines; D007211:Indoles; C046649:ropinirole; D000077465:Cabergoline