title: Retinal nerve fiber layer retardation measurements using a polarization-sensitive fundus camera.
abstract: To measure the retardation distribution of the optic retinal nerve fiber layer (RNFL) from a single image, we have developed a new polarization analysis system that is able to detect the Stokes vector using a fundus camera. The polarization analysis system is constructed with a CCD area image sensor, a linear polarizing plate, a microphase plate array, and a circularly polarized light illumination unit. In this system, the Stokes vector expressing the whole state of polarization is detected, and the influence of the background scattering in the retina and of the retardation caused by the cornea are numerically eliminated. The measurement method is based on the hypothesis that the retardation process of the eye optics can be quantified by a numerical equation that consists of a retardation matrix of all the polarization components. We show the method and the measurement results for normal eyes. Our results indicate that the present method may provide a useful means for the evaluation of retardation distribution of the RNFL.
authors.affiliation: Topcon Corporation, Eye Care Business Unit, 75-1 Hasunuma-chou, Itabashi-ku, Tokyo, Japan 174-8580. y.fukuma@topcon.co.jp
authors.forename: Yasufumi
authors.initials: Y
authors.lastname: Fukuma
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Okazaki
authors.forename: Takashi
authors.initials: T
authors.lastname: Shioiri
authors.forename: Yukio
authors.initials: Y
authors.lastname: Iida
authors.forename: Hisao
authors.initials: H
authors.lastname: Kikuta
authors.forename: Motohiro
authors.initials: M
authors.lastname: Shirakashi
authors.forename: Kiyoshi
authors.initials: K
authors.lastname: Yaoeda
authors.forename: Haruki
authors.initials: H
authors.lastname: Abe
authors.forename: Kazuhiko
authors.initials: K
authors.lastname: Ohnuma
mesh_terms: D000328:Adult; D001718:Birefringence; D003941:Diagnostic Techniques, Ophthalmological / Q000295:instrumentation* / Q000706:statistics & numerical data; D005260:Female; D006801:Humans; D019721:Ophthalmoscopes; D055096:Optical Devices; D055620:Optical Phenomena; D012160:Retina / Q000033:anatomy & histology* / Q000502:physiology; D055815:Young Adult