title: Heavy metal chelation in neurotoxic exposures.
abstract: Metals such as iron and copper are critical to living organisms, whereas other metals such as lead and arsenic have no known biologic role. Any metals in large amounts may cause toxicity. Many metals cause pervasive systemic effects involving the nervous system, which can be subtle in some cases. Although challenging, the diagnosis and treatment of metal poisoning can be made based on history, physical examination, and the proper use of metal testing. This article focuses on the use, and misuse, of chelation in the diagnosis and management of metal intoxication.
authors.affiliation: Department of Emergency Medicine, New York University School of Medicine, Bellevue Hospital Center, New York, NY, USA. jangd01@nyumc.org
authors.forename: David H
authors.initials: DH
authors.lastname: Jang
authors.forename: Robert S
authors.initials: RS
authors.lastname: Hoffman
mesh_terms: D002614:Chelating Agents; D015913:Chelation Therapy; D000075322:Heavy Metal Poisoning; D006801:Humans; D020258:Neurotoxicity Syndromes / Q000628:therapy*
chemical_list: D002614:Chelating Agents