title: Auditory N1 as a change-related automatic response.
abstract: To test the hypothesis that the N1 component of auditory evoked potentials (AEPs) is one form of the change-related response elicited by an abrupt change in sound pressure from a silent background, two AEP experiments were conducted. Change-N1 was evoked by a test stimulus at 70dB following a 3-s conditioning stimulus of 0-69dB. On-N1 was evoked by the test sound alone at various sound pressures. As the physical difference between stimuli increased, the amplitude of Change-N1 increased, and the latency shortened. The amplitude and latency of On-N1 showed a similar pattern to the Change-N1 response. These results support the idea that On-N1 is a change-related component elicited by a sound pressure change.
authors.affiliation: Department of Integrative Physiology, National Institute for Physiological Sciences, Myodaiji, Okazaki 444-8585, Japan. nisihara@aichi-med-u.ac.jp
authors.forename: Makoto
authors.initials: M
authors.lastname: Nishihara
authors.forename: Koji
authors.initials: K
authors.lastname: Inui
authors.forename: Eishi
authors.initials: E
authors.lastname: Motomura
authors.forename: Naofumi
authors.initials: N
authors.lastname: Otsuru
authors.forename: Takahiro
authors.initials: T
authors.lastname: Ushida
authors.forename: Ryusuke
authors.initials: R
authors.lastname: Kakigi
mesh_terms: D000161:Acoustic Stimulation / Q000379:methods*; D000328:Adult; D005072:Evoked Potentials, Auditory / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011930:Reaction Time / Q000502:physiology*