title: The grey mouse lemur: a non-human primate model for ageing studies.
abstract: The use of non-human primate models is required to understand the ageing process and evaluate new therapies against age-associated pathologies. The present article summarizes all the contributions of the grey mouse lemur Microcebus murinus, a small nocturnal prosimian primate, to the understanding of the mechanisms of ageing. Results from studies of both healthy and pathological ageing research on the grey mouse lemur demonstrated that this animal is a unique model to study age-dependent changes in endocrine systems, biological rhythms, thermoregulation, sensorial, cerebral and cognitive functions.
authors.affiliation: CNRS UMR 7179, MNHN, Brunoy, France.
authors.forename: S
authors.initials: S
authors.lastname: Languille
authors.forename: S
authors.initials: S
authors.lastname: Blanc
authors.forename: O
authors.initials: O
authors.lastname: Blin
authors.forename: C I
authors.initials: CI
authors.lastname: Canale
authors.forename: A
authors.initials: A
authors.lastname: Dal-Pan
authors.forename: G
authors.initials: G
authors.lastname: Devau
authors.forename: M
authors.initials: M
authors.lastname: Dhenain
authors.forename: O
authors.initials: O
authors.lastname: Dorieux
authors.forename: J
authors.initials: J
authors.lastname: Epelbaum
authors.forename: D
authors.initials: D
authors.lastname: Gomez
authors.forename: I
authors.initials: I
authors.lastname: Hardy
authors.forename: P-Y
authors.initials: PY
authors.lastname: Henry
authors.forename: E A
authors.initials: EA
authors.lastname: Irving
authors.forename: J
authors.initials: J
authors.lastname: Marchal
authors.forename: N
authors.initials: N
authors.lastname: Mestre-Francés
authors.forename: M
authors.initials: M
authors.lastname: Perret
authors.forename: J-L
authors.initials: JL
authors.lastname: Picq
authors.forename: F
authors.initials: F
authors.lastname: Pifferi
authors.forename: A
authors.initials: A
authors.lastname: Rahman
authors.forename: E
authors.initials: E
authors.lastname: Schenker
authors.forename: J
authors.initials: J
authors.lastname: Terrien
authors.forename: M
authors.initials: M
authors.lastname: Théry
authors.forename: J-M
authors.initials: JM
authors.lastname: Verdier
authors.forename: F
authors.initials: F
authors.lastname: Aujard
mesh_terms: D000375:Aging / Q000473:pathology* / Q000502:physiology*; D000818:Animals; D016565:Cheirogaleidae / Q000502:physiology*; D006801:Humans; D023421:Models, Animal; D013045:Species Specificity; D057170:Translational Research, Biomedical / Q000379:methods / Q000639:trends