title: Factors influencing the time of sentinel node visualization in breast cancer patients using intradermal injection of the radiotracer.
abstract: BACKGROUND
  The objective of our study was to determine the important factors that have influence on the time of sentinel node visualization using intradermal injection of (99m)Tc-antimony sulfide colloid.
  
  
  METHODS
  Two hundred fifty consecutive patients with the diagnosis of early-stage breast cancer were evaluated. Anterior and lateral views were acquired in various intervals after intradermal injection of the tracer until 180 minutes or visualization of the sentinel node. The effect of several variables on the time of sentinel node visualization was evaluated by univariate and multivariate analyses.
  
  
  RESULTS
  The time of sentinel node visualization was significantly correlated with age, body mass index (BMI), and interval between biopsy and sentinel node mapping. Standardized beta values for these variables were .1, .3, -.55 respectively.
  
  
  CONCLUSIONS
  Older age and higher BMI can result in slow sentinel node visualization. Longer interval between biopsy and sentinel node mapping can be associated with rapid sentinel node detection.
authors.affiliation: Surgical Oncology Research Center, Mashhad University of Medical Sciences, Islamic Republic of Iran.
authors.forename: Mohsen
authors.initials: M
authors.lastname: Aliakbarian
authors.forename: Bahram
authors.initials: B
authors.lastname: Memar
authors.forename: Ali
authors.initials: A
authors.lastname: Jangjoo
authors.forename: Seyed Rasoul
authors.initials: SR
authors.lastname: Zakavi
authors.forename: Vahid
authors.initials: V
authors.lastname: Reza Dabbagh Kakhki
authors.forename: Kamran
authors.initials: K
authors.lastname: Aryana
authors.forename: Mohammad Naser
authors.initials: MN
authors.lastname: Forghani
authors.forename: Ramin
authors.initials: R
authors.lastname: Sadeghi
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000704:Analysis of Variance; D000965:Antimony / Q000008:administration & dosage*; D001365:Axilla; D015992:Body Mass Index; D001943:Breast Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology*; D005260:Female; D006801:Humans; D007271:Injections, Intradermal; D008198:Lymph Nodes / Q000000981:diagnostic imaging* / Q000473:pathology*; D008875:Middle Aged; D009367:Neoplasm Staging; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals / Q000008:administration & dosage*; D021701:Sentinel Lymph Node Biopsy / Q000379:methods; D017556:Technetium Compounds / Q000008:administration & dosage*; D013997:Time Factors
chemical_list: D019275:Radiopharmaceuticals; D017556:Technetium Compounds; C019096:technetium Tc 99m antimony sulfide; D000965:Antimony