title: Phenylketonuria with acute myeloblastic leukemia in a 9-year-old boy: reporting a rare case.
abstract: Phenylketonuria is a genetic metabolic disorder resulting in phenylalanine accumulation in blood. Phenylacetate, which is an abnormal phenylalanine metabolities, was hypothesized to have anticancer activity. Two-years-old boy was diagnosed with classical phenylketonuria because of mental motor retardation. When the patient was 9-year-old, he developed acute myeloblastic leukemia. Here, we present the case with phenylketonuria and acute myeloblastic leukemia because of its extreme rarity.
authors.affiliation: Division of Hematology and Oncology, Department of Pediatrics, Erciyes University, Kayseri, Turkey.
authors.forename: Turkan
authors.initials: T
authors.lastname: Patiroglu
authors.forename: Ekrem
authors.initials: E
authors.lastname: Unal
authors.forename: Fatih
authors.initials: F
authors.lastname: Kardas
authors.forename: Mehmet Akif
authors.initials: MA
authors.lastname: Ozdemir
authors.forename: Musa
authors.initials: M
authors.lastname: Karakukcu
authors.forename: Ozlem
authors.initials: O
authors.lastname: Sayilmaz
mesh_terms: D002648:Child; D006801:Humans; D008607:Intellectual Disability / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D015470:Leukemia, Myeloid, Acute / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D008297:Male; D010661:Phenylketonurias / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D011379:Prognosis