title: Tumor targeted nanoparticles: a modern day Trojan horse.
abstract: During the past few decades, particles of various compositions have been engineered in ever smaller sizes to function in both diagnostic and therapeutic capacities. Nanoparticles are now available on a scale similar to many biological molecules and infectious agents, thereby opening the possibility of biological intervention on the molecular level. Several recent timely reports summarize nanoparticle properties and potential clinical applications in early-stage clinical trials.
authors.affiliation: Division of Thoracic Surgery, Department of Surgery, Brigham and Women's Hospital, Boston, Massachusetts 02215, USA.
authors.forename: Denis
authors.initials: D
authors.lastname: Gilmore
authors.forename: Yolonda L
authors.initials: YL
authors.lastname: Colson
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000008:administration & dosage*; D004337:Drug Carriers; D018014:Gene Transfer Techniques; D015316:Genetic Therapy / Q000379:methods*; D006801:Humans; D053758:Nanoparticles; D009369:Neoplasms / Q000175:diagnosis* / Q000235:genetics / Q000628:therapy*; D011237:Predictive Value of Tests
chemical_list: D000970:Antineoplastic Agents; D004337:Drug Carriers