title: Metabolic syndrome and chronic kidney disease in a rural Chinese population.
abstract: BACKGROUND
  Metabolic syndrome is a common risk factor for cardiovascular disease. Chronic kidney disease (CKD) is a worldwide public health problem. We investigated the association between metabolic syndrome and CKD in a rural Chinese population.
  
  
  METHODS
  This was a cross-sectional study using data from the Handan Eye Study.
  
  
  RESULTS
  4944 of participants aged ≥ 30 y were included in this analysis. Participants with metabolic syndrome had a higher prevalence of CKD (20.9% vs.15.8%, P<0.001) than those without. As the number of metabolic syndrome components increased, so did the prevalence of CKD (P<0.001). The multivariate-adjusted odds ratio (OR) of chronic kidney disease in participants with metabolic syndrome was 1.293 (95% CI 1.093-1.529) compared with those without. In multivariate logistic regression analysis, high blood pressure (OR 1.348; 95% CI 1.122-1.619) and high fasting glucose (OR 1.501; 95% CI 1.235-1.794) were independently associated with the risk for CKD. Compared with participants without any component, multivariate adjusted OR for CKD was 1.316 (95%CI 1.004-1.723), 1.397(95%CI 1.038-1.882), 1.672 (95%CI 1.183-2.363) for those with 2, 3, 4 or 5 components, respectively.
  
  
  CONCLUSIONS
  In this rural Chinese population aged ≥ 30 y, metabolic syndrome was associated with CKD.
authors.affiliation: Department of Nephrology, Beijing TongRen Hospital, Capital Medical University, Beijing, China.
authors.forename: LiPing
authors.initials: L
authors.lastname: Jiang
authors.forename: YuanBo
authors.initials: Y
authors.lastname: Liang
authors.forename: Bo
authors.initials: B
authors.lastname: Qiu
authors.forename: FengHua
authors.initials: F
authors.lastname: Wang
authors.forename: XinRong
authors.initials: X
authors.lastname: Duan
authors.forename: XiaoHui
authors.initials: X
authors.lastname: Yang
authors.forename: JinGang
authors.initials: J
authors.lastname: Yang
authors.forename: Wen
authors.initials: W
authors.lastname: Huang
authors.forename: NingLi
authors.initials: N
authors.lastname: Wang
mesh_terms: D044466:Asian People / Q000706:statistics & numerical data; D002681:China / Q000453:epidemiology / Q000208:ethnology; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D024821:Metabolic Syndrome / Q000097:blood / Q000150:complications* / Q000175:diagnosis / Q000453:epidemiology; D008875:Middle Aged; D051436:Renal Insufficiency, Chronic / Q000097:blood / Q000150:complications* / Q000175:diagnosis / Q000453:epidemiology; D012423:Rural Health / Q000706:statistics & numerical data; D012424:Rural Population