title: Meigs' syndrome with elevated serum cancer antigen 125 levels in a case of ovarian sclerosing stromal tumor.
abstract: OBJECTIVE
  Meigs' syndrome presenting as an ovarian tumor with elevated serum cancer antigen 125 (CA 125) levels is unusual. Only 37 cases have been reported, including three cases of ovarian sclerosing stromal tumor (SCT). Many reports have suggested that the presence of ascites is the major factor inducing mesothelial expression of CA 125.
  
  
  METHODS
  An 18-year-old woman presented with massive ascites, elevated serum CA 125 levels, and radiographic evidence of ovarian tumor. The histological and immunohistochemical examinations revealed a benign SCT.
  
  
  CONCLUSIONS
  SCT is a benign ovarian tumor and complete excision is curative. We also review all 37 cases and discuss possible mechanisms of Meigs' syndrome and elevated serum CA 125 level.
authors.affiliation: Department of Surgical Pathology, Changhua Christian Hospital, Changhua, Taiwan.
authors.forename: Jia-Hung
authors.initials: JH
authors.lastname: Liou
authors.forename: Tzu Cheng
authors.initials: TC
authors.lastname: Su
authors.forename: Jui-Chang
authors.initials: JC
authors.lastname: Hsu
mesh_terms: D000293:Adolescent; D018394:CA-125 Antigen / Q000097:blood*; D005260:Female; D006801:Humans; D008539:Meigs Syndrome / Q000097:blood* / Q000175:diagnosis* / Q000601:surgery; D018312:Sex Cord-Gonadal Stromal Tumors / Q000097:blood* / Q000175:diagnosis* / Q000601:surgery
chemical_list: D018394:CA-125 Antigen