title: Characterization and properties of novel gallium-doped calcium phosphate ceramics.
abstract: Addition of a gallium (Ga) precursor in the typical reaction protocols used for the preparation of β-tricalcium phosphate (β-TCP) led to novel Ga-doped β-TCP ceramics with rhombohedral structures (R3c space group). From the refinement of their X-ray diffraction patterns, it was found that the incorporation of Ga in the β-TCP network occurs by substitution of one of the five calcium (Ca) sites, while occupation of another Ca site decreases in inverse proportion to the Ga content in the structure. The Ga local environment and the modification of the phosphorus environments due to the Ga/Ca substitution in Ga-doped β-TCP compounds are probed using (31)P and (71)Ga magic-angle spinning NMR. A decrease of the unit cell volume is observed with increasing Ga content, together with improved mechanical properties. Indeed, the compressive strength of these new bioceramics is enhanced in direct proportion of the Ga content, up to a 2.6-fold increase as compared to pure β-TCP.
authors.affiliation: Graftys SA, Eiffel Park, Bâtiment D, 415 Rue Claude Nicolas Ledoux, Pôle d'activités d'Aix en Provence, 13854 Aix en Provence CEDEX 3, France.
authors.forename: Charlotte
authors.initials: C
authors.lastname: Mellier
authors.forename: Franck
authors.initials: F
authors.lastname: Fayon
authors.forename: Verena
authors.initials: V
authors.lastname: Schnitzler
authors.forename: Philippe
authors.initials: P
authors.lastname: Deniard
authors.forename: Mathieu
authors.initials: M
authors.lastname: Allix
authors.forename: Sophie
authors.initials: S
authors.lastname: Quillard
authors.forename: Dominique
authors.initials: D
authors.lastname: Massiot
authors.forename: Jean-Michel
authors.initials: JM
authors.lastname: Bouler
authors.forename: Bruno
authors.initials: B
authors.lastname: Bujoli
authors.forename: Pascal
authors.initials: P
authors.lastname: Janvier
mesh_terms: D002130:Calcium Phosphates / Q000737:chemistry*; D002516:Ceramics / Q000737:chemistry*; D005708:Gallium / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy / Q000592:standards; D010759:Phosphorus Isotopes; D012015:Reference Standards
chemical_list: D002130:Calcium Phosphates; D010759:Phosphorus Isotopes; C020243:calcium phosphate; D005708:Gallium