title: Total synthesis of the natural product (±)-dibromophakellin and analogues.
abstract: (±)-Dibromophakellin has been synthesized in two steps from a known alkene intermediate. The key step in the synthesis is the NBS olefin activation to facilitate the addition of a guanidine molecule across the double bond.
authors.affiliation: Department of Chemistry, Michigan State University, East Lansing, Michigan 48824, USA.
authors.forename: Nicole M
authors.initials: NM
authors.lastname: Hewlett
authors.forename: Jetze J
authors.initials: JJ
authors.lastname: Tepe
mesh_terms: D001685:Biological Factors / Q000138:chemical synthesis* / Q000737:chemistry; D006576:Heterocyclic Compounds, 4 or More Rings / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D001685:Biological Factors; D006576:Heterocyclic Compounds, 4 or More Rings; C541047:dibromophakellin