title: Exploring natural products for new taste sensations.
abstract: This paper discusses the discovery of uncommon taste or trigeminal active compounds and their associated sensory analysis using human tasting panels with the aim of enhancing the overall taste experience whilst reducing where possible the sugar and salt content of foods. The first example outlines the discovery of the sensory quality attributes of (R)-2-(carboxymethylamino)propanoic acid, named (R)-strombine, as assessed by a panel of 47 subjects to confirm its contribution to the typical taste of scallop muscle. The second example discusses the pungency and trigeminal effect of polygodial, which is compared with piperine and capsaicin, as well as the elucidation of a new structure eliciting a trigeminal effect, (+/-)-trans-2,3,3a,7a-tetrahydro-1 H-indene-4-carbaldehyde, discovered in Amomum tsao-ko. Finally, the time intensity trigeminal effect of (-)-menthol is compared with (1R,2RS,4RS)-1-isopropyl-4-methylbicyclo[3.1.0]hexan-2-ol, named dihydroumbellulol, a new cooling compound obtained by hemi-synthesis from umbellulone extracted from Umbellularia californica Nutt.
authors.affiliation: Firmenich SA, Corporate R&D Division, P.O. Box 239, CH-1211 Geneva 8. christian.starkenmann@firmenich.com
authors.forename: Christian
authors.initials: C
authors.lastname: Starkenmann
authors.forename: Isabelle
authors.initials: I
authors.lastname: Cayeux
authors.forename: Anthony A
authors.initials: AA
authors.lastname: Birkbeck
mesh_terms: D001688:Biological Products / Q000737:chemistry*; D005421:Flavoring Agents / Q000737:chemistry*; D006801:Humans; D015394:Molecular Structure; D014276:Trigeminal Nerve / Q000187:drug effects
chemical_list: D001688:Biological Products; D005421:Flavoring Agents