title: Three-Dimensional Structure of Arabidopsis thaliana Lipase Predicted by Homology Modeling Method.
abstract: Triacylglycerol lipases have been thoroughly characterized in mammals and microorganisms. By contrast, very little is known about plant lipases. In this investigation, a homology model of Arabidopsis thaliana lipase (NP_179126) was constructed using a human gastric lipase (PDB ID: 1HLG), as a template for model building. This model was then assessed for stereochemical quality and side chain environment. Natural substrates: tributyrin, trioctanoin and triolen were docked into the model to investigate ligand-substrate interaction.
authors.affiliation: Unité de Protéomie Fonctionnelle and Biopréservation Alimentaire, Institut Supérieur des Sciences Biologiques Appliquées de Tunis, Université Tunis El Manar, Tunisie.
authors.forename: Abdelmonaem
authors.initials: A
authors.lastname: Messaoudi
authors.forename: Hatem
authors.initials: H
authors.lastname: Belguith
authors.forename: Jeannette
authors.initials: J
authors.lastname: Ben Hamida