title: Keratoameloblastoma: complex histologic variant of ameloblastoma.
abstract: Keratoameloblastoma is a rare subtype of ameloblastoma that has been reported only 12 times previously in the literature. Ameloblastomas are benign, locally aggressive neoplasms that constitute approximately 1% of odontogenic neoplasms. The mandible is involved in 80% of cases and the maxilla 20%. Clinically, these appear as solid, unicystic, multicystic, and mixed solid and multicystic tumors. Histologically, these are classified as follicular, plexiform, acanthomatous, and granular cell. Less common histologic variants are clear cell, desmoplastic, basal cell, papilliferous, and keratoameloblastoma. This report presents a new case to the literature, reviews histologic findings and radiographic appearance, and discusses the clinical significance of this tumor with respect to treatment based on currently available literature.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Cook County Hospital, Chicago, IL, USA.
authors.forename: John M
authors.initials: JM
authors.lastname: Sisto
authors.forename: Gregory G
authors.initials: GG
authors.lastname: Olsen
mesh_terms: D000328:Adult; D000564:Ameloblastoma / Q000175:diagnosis*; D001707:Biopsy, Needle; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008336:Mandibular Diseases / Q000175:diagnosis; D008339:Mandibular Neoplasms / Q000175:diagnosis*; D009807:Odontogenic Cysts / Q000175:diagnosis; D010173:Palpation; D011862:Radiography, Panoramic; D014057:Tomography, X-Ray Computed