title: Analyzing Chinese patients with post-operative acute kidney injury.
abstract: BACKGROUND
  To investigate clinical characteristics and risk factors of Chinese patients with post-operative acute kidney injury (PO-AKI).
  
  
  METHODS
  Patients with PO-AKI in Ruijin Hospital from December 1997 to December 2005 were retrospectively studied.
  
  
  RESULTS
  Patients' mean age was 62.2 ± 18.1 years. There were 111 males and 57 females. The mean serum creatinine at diagnosis was 370.41 ± 320.92 μmol/L and the mean estimated glomerular filtration rate was 33.56 ± 24.24 mL/min. For the outcome of the patients, 38 died and the mortality rate was 22.6%. There were 17 patients (10.1%) with Acute Dialysis Quality Initiative-RIFLE (risk-injury-failure-loss-end classification) phase R, 21 (12.5%) with phase I, and 130 (77.4%) with phase F. There was no significant difference in mortality regarding patients who underwent different types of surgeries. For the risk factors related to PO-AKI, acute tubular necrosis (ATN) increased relative risk of mortality PO-AKI (odds ratio = 7.089, 95% confidence interval = 2.069-24.288, p < 0.001). Multivariate regression models showed that ATN had a positive correlation with mortality of PO-AKI.
  
  
  CONCLUSIONS
  PO-AKI is one of the most common causes of AKI in patients who underwent operations. Special attention should be paid to risk factors related to PO-AKI in order to improve prognosis.
authors.affiliation: Department of Nephrology, Shanghai Ruijin Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, PR China.
authors.forename: Wen
authors.initials: W
authors.lastname: Zhang
authors.forename: Ping-Yan
authors.initials: PY
authors.lastname: Shen
authors.forename: Yong-Xi
authors.initials: YX
authors.lastname: Chen
authors.forename: Ping
authors.initials: P
authors.lastname: Zhu
authors.forename: Hao
authors.initials: H
authors.lastname: Shi
authors.forename: Xiao
authors.initials: X
authors.lastname: Li
authors.forename: Yao-Wen
authors.initials: YW
authors.lastname: Xu
authors.forename: Hong
authors.initials: H
authors.lastname: Ren
authors.forename: Nan
authors.initials: N
authors.lastname: Chen
mesh_terms: D058186:Acute Kidney Injury / Q000175:diagnosis / Q000453:epidemiology; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002681:China; D006801:Humans; D008875:Middle Aged; D011183:Postoperative Complications / Q000175:diagnosis / Q000453:epidemiology; D012189:Retrospective Studies; D012307:Risk Factors; D015996:Survival Rate; D055815:Young Adult