title: Guidance on minimally important clinical difference and trial size is needed.
authors.forename: Jonathan A
authors.initials: JA
authors.lastname: Cook
authors.forename: Craig R
authors.initials: CR
authors.lastname: Ramsay
authors.forename: Luke D
authors.initials: LD
authors.lastname: Vale
mesh_terms: D002908:Chronic Disease; D004185:Disability Evaluation; D006801:Humans; D017116:Low Back Pain / Q000601:surgery*; D019919:Prosthesis Implantation; D016032:Randomized Controlled Trials as Topic; D018401:Sample Size