title: Characteristics of HIV-infected women and factors associated with HCV seropositivity in the Republic of Georgia.
abstract: BACKGROUND
  The aim of this study was to describe the extent of the HIV epidemic among women in the Republic of Georgia and to identify factors associated with HCV co-infection in this population.
  
  
  RESULTS
  All women aged ≥18 years who were diagnosed with HIV between 1989 and 2006 were identified through the National HIV/AIDS surveillance database. Medical records were reviewed for demographic characteristics, risk factors and HCV serostatus. A total of 249 women were identified. Only 4% declared injection drug use (IDU); sex work was reported by 9%. Substantial risk factors were identified among the women's sexual partners, nearly 69% of whom were IDUs, 84% were HIV positive and 66% HCV positive. Seventeen percent of women were seropositive for HCV. Factors significantly associated with HCV seropositivity in bivariate analyses among non-IDU women were partner IDU+ [Prevalence ratio (PR): 4.5 (95% CI: 1.4, 14.2)], and partner HCV+ [PR: 7.2 (95% CI: 1.8, 29.5)].
  
  
  CONCLUSIONS
  The HIV epidemic in the Republic of Georgia is closely tied to the IDU community. Evidence-based interventions targeting IDU and partners of IDU are urgently required to halt the spread of the HIV epidemic in the country.
authors.affiliation: Infectious Diseases, AIDS and Clinical Immunology Research Center, 16 Al, Kazbegi Avenue, Tbilisi 0160, Georgia. nikoloch@yahoo.com.
authors.forename: Nikoloz
authors.initials: N
authors.lastname: Chkhartishvili
authors.forename: Louise-Anne
authors.initials: LA
authors.lastname: McNutt
authors.forename: Perry F
authors.initials: PF
authors.lastname: Smith
authors.forename: Tengiz
authors.initials: T
authors.lastname: Tsertsvadze