title: [Disturbances of carbohydrate metabolism and factors stimulating its development in ontogenesis].
abstract: The review contains comprehencive literature data about the effect of unfavourable factors on forming of islet's apparatus of pancreas and the development of disturbances of carbohydrate metabolism in ontogenesis. The analyses of current sources showed that the effect of unfavourable factors in embrional period and early childhood defines the development of some disturbances of carbohydrate metabolism in adult life. In the process of ontogenesis the combination of the reduction of islet's apparatus functional activity and risk factors (age, abundant weight, stress, hypodinamia) can lead to the development of metabolic syndrome, diabetes mellitus and obesity.
authors.forename: S S
authors.initials: SS
authors.lastname: Moĭsa
authors.forename: A D
authors.initials: AD
authors.lastname: Nozdrachev
mesh_terms: D000375:Aging / Q000378:metabolism*; D000818:Animals; D050260:Carbohydrate Metabolism / Q000502:physiology*; D006801:Humans; D007515:Islets of Langerhans / Q000378:metabolism / Q000502:physiology; D024821:Metabolic Syndrome / Q000196:embryology / Q000209:etiology / Q000378:metabolism*; D012307:Risk Factors