title: Prediction of β-lactoglobulin genotypes based on milk Fourier transform infrared spectra.
abstract: β-Lactoglobulin (β-LG) genotypes are associated with differences in bovine milk protein composition. Therefore, β-LG genotypes are of direct relevance for the dairy industry. In this study, we predicted β-lactoglobulin genotypes based on routinely recorded milk Fourier transform infrared spectra using 500 calibration samples. The results show that 76% of the cows carrying the β-LG AA genotype, 80% of the cows carrying the β-LG AB genotype, and 66% of the cows carrying the β-LG BB genotype were predicted correctly. Furthermore, the prediction of β-LG genotypes based on Fourier transform infrared spectra showed a repeatability of 0.85. We discuss how the combined use of predicted β-LG genotypes, pedigree information, and β-LG genotypes derived using other methods could lead to further improvement in the percentage of correctly predicted β-LG genotypes. The presented methodology is easy and inexpensive and could ultimately provide β-LG genotypes at the individual cow level.
authors.affiliation: Animal Breeding and Genomics Centre, Wageningen University, PO Box 338, 6700 AH, Wageningen, the Netherlands. marc.rutten@wur.nl
authors.forename: M J M
authors.initials: MJ
authors.lastname: Rutten
authors.forename: H
authors.initials: H
authors.lastname: Bovenhuis
authors.forename: J M L
authors.initials: JM
authors.lastname: Heck
authors.forename: J A M
authors.initials: JA
authors.lastname: van Arendonk
mesh_terms: D000818:Animals; D002417:Cattle / Q000235:genetics; D003612:Dairying; D005260:Female; D005787:Gene Frequency / Q000235:genetics; D005838:Genotype; D006579:Heterozygote; D007782:Lactoglobulins / Q000032:analysis / Q000235:genetics*; D008892:Milk / Q000737:chemistry*; D017550:Spectroscopy, Fourier Transform Infrared / Q000662:veterinary
chemical_list: D007782:Lactoglobulins; C064259:beta-lactoglobin W