title: Aichi virus shedding in high concentrations in patients with acute diarrhea.
abstract: We assessed Aichi virus shedding in patients with gastroenteritis and negative test results for other viral and bacterial infections. High concentrations of up to 1.32 × 1012 RNA copies/g stool were found in 10 (2.0%) of 499 outpatients sampled in northern Germany, 2004. These data substantiate Aichi virus pathogenicity in humans.
authors.affiliation: University of Bonn Medical Centre, Bonn, Germany.
authors.forename: Jan Felix
authors.initials: JF
authors.lastname: Drexler
authors.forename: Sigrid
authors.initials: S
authors.lastname: Baumgarte
authors.forename: Luciano Kleber
authors.initials: LK
authors.lastname: de Souza Luna
authors.forename: Monika
authors.initials: M
authors.lastname: Eschbach-Bludau
authors.forename: Alexander N
authors.initials: AN
authors.lastname: Lukashev
authors.forename: Christian
authors.initials: C
authors.lastname: Drosten
mesh_terms: D020121:5' Untranslated Regions / Q000235:genetics; D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D003967:Diarrhea / Q000453:epidemiology* / Q000821:virology*; D005243:Feces / Q000821:virology*; D018628:Gene Dosage; D005858:Germany / Q000453:epidemiology; D006801:Humans; D007223:Infant; D052699:Kobuvirus / Q000145:classification / Q000235:genetics / Q000302:isolation & purification* / Q000472:pathogenicity*; D008875:Middle Aged; D008969:Molecular Sequence Data; D010850:Picornaviridae Infections / Q000453:epidemiology / Q000821:virology; D012367:RNA, Viral / Q000032:analysis / Q000302:isolation & purification; D020133:Reverse Transcriptase Polymerase Chain Reaction; D017422:Sequence Analysis, DNA; D017201:Virus Shedding; D055815:Young Adult
chemical_list: D020121:5' Untranslated Regions; D012367:RNA, Viral