title: Value of the BI-RADS classification in MR-Mammography for diagnosis of benign and malignant breast tumors.
abstract: OBJECTIVE
  To assess whether the BI-RADS classification in MR-Mammography (MRM) can distinguish between benign and malignant lesions.
  
  
  METHODS
  207 MRM investigations were categorised according to BI-RADS. The results were compared to histology. All MRM studies were interpreted by two examiners. Statistical significance for the accuracy of MRM was calculated.
  
  
  RESULTS
  A significant correlation between specific histology and MRM-tumour-morphology could not be reported. Mass (68%) was significant for malignancy. Significance raised with irregular shape (88%), spiculated margin (97%), rim enhancement (98%), fast initial increase (90%), post initial plateau (65%), and intermediate T2 result (82%). Highly significant for benignity was an oval mass (79%), slow initial increase (94%) and a hyperintense T2 result (77%), also an inconspicuous MRM result (77%) was often seen in benign histology. Symmetry (90%) and further post initial increase (90%) were significant, whereas a regional distribution (74%) was lowly significant for benignity.
  
  
  CONCLUSIONS
  On basis of the BI-RADS classification an objective comparability and statement of diagnosis could be made highly significant. Due to the fact of false-negative and false-positive MRM-results, histology is necessary.
authors.affiliation: Department of Cardiology and Pneumology, Heart Center, Georg-August-University of Göttingen, Robert-Koch-Strasse 40, 37075 Göttingen, Germany. csohns@med.uni-goettingen.de
authors.forename: Christian
authors.initials: C
authors.lastname: Sohns
authors.forename: Martin
authors.initials: M
authors.lastname: Scherrer
authors.forename: Wieland
authors.initials: W
authors.lastname: Staab
authors.forename: Silvia
authors.initials: S
authors.lastname: Obenauer
mesh_terms: D000465:Algorithms; D001940:Breast; D001941:Breast Diseases / Q000145:classification* / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D001943:Breast Neoplasms / Q000145:classification / Q000175:diagnosis; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008327:Mammography; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D015588:Observer Variation; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity