title: The effect of major depression on postexercise cardiovascular recovery.
abstract: Major depressive disorder (MDD) is associated with increased cardiovascular (CV) mortality. Dysfunctional autonomic control of the CV system may represent a mechanism explaining this relationship. Poor CV recovery after exercise, indicative of dysfunctional autonomic control of the CV system, predicts CV events and death. This is the first study to examine the association between MDD and postexercise CV recovery. Some 886 patients underwent exercise stress tests. Heart rate (HR), systolic blood pressure, and diastolic blood pressure were measured at rest, peak exercise, 1 min, and 5 min after exercise. Patients with MDD had slower HR recovery (p=.026) 1 min after exercise than non-MDD patients. No other effects of MDD were found. MDD is accompanied by a dysregulation in autonomic control of exercise-related CV recovery, suggesting that depressed individuals have a slow parasympathetic recovery from exercise.
authors.affiliation: Montreal Behavioural Medicine Centre, Montréal, Québec, CanadaResearch Centre, Montreal Heart Institute, Montréal, Québec, CanadaDepartment of Psychology, McGill University, Montréal, Québec, CanadaResearch Centre, Hôpital du Sacré-Cœur, Montréal, Montréal, Québec, CanadaDepartment of Psychology, University of Québec at Montréal, Montréal, Québec, CanadaDepartment of Psychology, University of Calgary, Calgary, Alberta, CanadaDepartment of Exercise Science, Concordia University, Montréal, Québec, Canada.
authors.forename: Jennifer L
authors.initials: JL
authors.lastname: Gordon
authors.affiliation: Montreal Behavioural Medicine Centre, Montréal, Québec, CanadaResearch Centre, Montreal Heart Institute, Montréal, Québec, CanadaDepartment of Psychology, McGill University, Montréal, Québec, CanadaResearch Centre, Hôpital du Sacré-Cœur, Montréal, Montréal, Québec, CanadaDepartment of Psychology, University of Québec at Montréal, Montréal, Québec, CanadaDepartment of Psychology, University of Calgary, Calgary, Alberta, CanadaDepartment of Exercise Science, Concordia University, Montréal, Québec, Canada.
authors.forename: Blaine
authors.initials: B
authors.lastname: Ditto
authors.affiliation: Montreal Behavioural Medicine Centre, Montréal, Québec, CanadaResearch Centre, Montreal Heart Institute, Montréal, Québec, CanadaDepartment of Psychology, McGill University, Montréal, Québec, CanadaResearch Centre, Hôpital du Sacré-Cœur, Montréal, Montréal, Québec, CanadaDepartment of Psychology, University of Québec at Montréal, Montréal, Québec, CanadaDepartment of Psychology, University of Calgary, Calgary, Alberta, CanadaDepartment of Exercise Science, Concordia University, Montréal, Québec, Canada.
authors.forename: Kim L
authors.initials: KL
authors.lastname: Lavoie
authors.affiliation: Montreal Behavioural Medicine Centre, Montréal, Québec, CanadaResearch Centre, Montreal Heart Institute, Montréal, Québec, CanadaDepartment of Psychology, McGill University, Montréal, Québec, CanadaResearch Centre, Hôpital du Sacré-Cœur, Montréal, Montréal, Québec, CanadaDepartment of Psychology, University of Québec at Montréal, Montréal, Québec, CanadaDepartment of Psychology, University of Calgary, Calgary, Alberta, CanadaDepartment of Exercise Science, Concordia University, Montréal, Québec, Canada.
authors.forename: Roxanne
authors.initials: R
authors.lastname: Pelletier
authors.affiliation: Montreal Behavioural Medicine Centre, Montréal, Québec, CanadaResearch Centre, Montreal Heart Institute, Montréal, Québec, CanadaDepartment of Psychology, McGill University, Montréal, Québec, CanadaResearch Centre, Hôpital du Sacré-Cœur, Montréal, Montréal, Québec, CanadaDepartment of Psychology, University of Québec at Montréal, Montréal, Québec, CanadaDepartment of Psychology, University of Calgary, Calgary, Alberta, CanadaDepartment of Exercise Science, Concordia University, Montréal, Québec, Canada.
authors.forename: Tavis S
authors.initials: TS
authors.lastname: Campbell
authors.affiliation: Montreal Behavioural Medicine Centre, Montréal, Québec, CanadaResearch Centre, Montreal Heart Institute, Montréal, Québec, CanadaDepartment of Psychology, McGill University, Montréal, Québec, CanadaResearch Centre, Hôpital du Sacré-Cœur, Montréal, Montréal, Québec, CanadaDepartment of Psychology, University of Québec at Montréal, Montréal, Québec, CanadaDepartment of Psychology, University of Calgary, Calgary, Alberta, CanadaDepartment of Exercise Science, Concordia University, Montréal, Québec, Canada.
authors.forename: André
authors.initials: A
authors.lastname: Arsenault
authors.affiliation: Montreal Behavioural Medicine Centre, Montréal, Québec, CanadaResearch Centre, Montreal Heart Institute, Montréal, Québec, CanadaDepartment of Psychology, McGill University, Montréal, Québec, CanadaResearch Centre, Hôpital du Sacré-Cœur, Montréal, Montréal, Québec, CanadaDepartment of Psychology, University of Québec at Montréal, Montréal, Québec, CanadaDepartment of Psychology, University of Calgary, Calgary, Alberta, CanadaDepartment of Exercise Science, Concordia University, Montréal, Québec, Canada.
authors.forename: Simon L
authors.initials: SL
authors.lastname: Bacon
mesh_terms: D000368:Aged; D001341:Autonomic Nervous System / Q000503:physiopathology*; D001794:Blood Pressure / Q000502:physiology*; D003865:Major Depressive Disorder / Q000503:physiopathology*; D015444:Exercise / Q000502:physiology*; D005080:Exercise Test; D005260:Female; D006339:Heart Rate / Q000502:physiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011795:Surveys and Questionnaires