title: Updates on Somatoform Disorders (SFMD) in Parkinson's Disease and Dementia with Lewy Bodies and discussion of phenomenology.
abstract: Somatoform Disorders (SFMD) were recently described in Parkinson Disease (PD) and Dementia with Lewy Bodies (DLB). The present paper updates the observations in our cohort of patients and further details clinical phenomenology. Of 3178 patients consecutively referred to our Institutions from 1999, 1572 subjects had neurodegenerative diseases and 1718 psychiatric disorders. After 2-9 years of follow up, 488 patients were labelled as PD, 415 as Alzheimer Disease, 162 as DLB, 48 as Progressive Supranuclear Palsy, 48 as Multiple System Atrophy and 49 as Fronto-Temporal Dementia. The frequency of SFMD (DSM-IV-TR criteria) was determined in each diagnostic category by direct observation of SFMD symptoms, psychiatric interviews, SCL 90Rss, collection of previous general practitioners and hospital charts. The frequency of SFMD was considerably higher in DLB (29 patients, 18%) and PD (37 patients, 7.5%) than in any other group (0-2%). The frequency of SFMD in psychiatric patients was 2%. SFMD in PD and DLB were characterised by motor and non-motor patterns and were often accompanied by catatonic signs consisting of posturing stereotypies and negativism (55%). SFMD symptoms preceded PD motor signs by 6 months-5 years in 92% of the 29 DLB and 37 PD patients and in 70% SFMD were recurrent at follow-up. In 93% of these patients, hypochondria was a preceding or concomitant background.
authors.affiliation: Department of Neuroscience and Imaging, Neurology University G.D'Annunzio of Chieti-Pescara, Italy. onofrj@unich.it
authors.forename: Marco
authors.initials: M
authors.lastname: Onofrj
authors.forename: Astrid
authors.initials: A
authors.lastname: Thomas
authors.forename: Pietro
authors.initials: P
authors.lastname: Tiraboschi
authors.forename: Gregor
authors.initials: G
authors.lastname: Wenning
authors.forename: Francesco
authors.initials: F
authors.lastname: Gambi
authors.forename: Gianna
authors.initials: G
authors.lastname: Sepede
authors.forename: Massimo
authors.initials: M
authors.lastname: Di Giannantonio
authors.forename: Caterina
authors.initials: C
authors.lastname: Di Carmine
authors.forename: Daniela
authors.initials: D
authors.lastname: Monaco
authors.forename: Valerio
authors.initials: V
authors.lastname: Maruotti
authors.forename: Fausta
authors.initials: F
authors.lastname: Ciccocioppo
authors.forename: Maria Chiara
authors.initials: MC
authors.lastname: D'Amico
authors.forename: Laura
authors.initials: L
authors.lastname: Bonanni
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003243:Consciousness; D005260:Female; D006801:Humans; D020961:Lewy Body Disease / Q000150:complications* / Q000453:epidemiology; D008297:Male; D010300:Parkinson Disease / Q000150:complications* / Q000453:epidemiology; D011569:Psychiatric Status Rating Scales; D012189:Retrospective Studies; D013001:Somatoform Disorders / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology / Q000523:psychology*