title: Cultural and linguistic validation of acne-QoL in French.
abstract: BACKGROUND
  Acne-Quality of Life (acne-QoL) is a facial acne-specific quality-of-life instrument developed in English.
  
  
  OBJECTIVE
  Our objective was to translate and validate acne-QoL in French and to establish the reliability and responsivity of this measure.
  
  
  METHODS
  Acne-QoL was translated into French (acne-QoLfr) in accordance with international methodological recommendations. The validated French version of the Cardiff Acne Disability Index (CADIfr) was used as a comparator. Acne patients in Quebec (n = 20) and France (n = 14) completed the acne-QoLfr and CADIfr on three occasions over 3 months (day 0, day 2-3, day 60-90).
  
  
  RESULTS
  A total of 34 patients were recruited. Pearson's correlation for total acne-QoLfr scores at day 0 and day 2-3 was 0.77. Of the four domains comprising the acne-QoLfr, correlations were highest for symptoms (0.85) and lowest for the role-emotional domain (0.66). At day 60-90, total acne-QoLfr scores increased by a mean of 19.7 points, reflecting improved quality-of-life with acne therapy and demonstrating responsivity of the instrument.
  
  
  CONCLUSIONS
  Acne-QoLfr is a linguistically and culturally validated tool for facial acne that is both reliable and responsive.
authors.affiliation: Department of Medicine, University of Western Ontario, London, ON, Canada. jerrytan@bellnet.ca
authors.forename: J
authors.initials: J
authors.lastname: Tan
authors.forename: A
authors.initials: A
authors.lastname: O'Toole
authors.forename: X
authors.initials: X
authors.lastname: Zhang
authors.forename: B
authors.initials: B
authors.lastname: Dreno
authors.forename: Y
authors.initials: Y
authors.lastname: Poulin
mesh_terms: D000152:Acne Vulgaris / Q000503:physiopathology* / Q000523:psychology; D000293:Adolescent; D000328:Adult; D003466:Cultural Characteristics; D005260:Female; D005602:France; D006801:Humans; D008037:Linguistics; D008297:Male; D008875:Middle Aged; D011788:Quality of Life; D055815:Young Adult