title: Anticancer activity of Tephrosia purpurea and Ficus religiosa using MCF 7 cell lines.
abstract: OBJECTIVE
  To investigate anticancer activity of different fractions of Tephrosia purpurea [TP] (Sharapunkha, Fabaceae) and Ficus religiosa [FR] (Peepal, Moraceae).
  
  
  METHODS
  The fractions of TP and FR were prepared and tested for in vitro anticancer activity using human MCF 7 cell line by trypan blue exclusion method.
  
  
  RESULTS
  The result showed that among all these fractions of TPI, TPIII, FRI and FRIII showed better anticancer activity compared to other fractions. The IC(50) value for TPI (152.4 μM), TPIII (158.71 μM), FRI (160.3 μM) and for FRIII (222.7 μM) was observed.
  
  
  CONCLUSIONS
  The present study shows anticancer potential of TP and FR fractions in MCF 7 cell line.
authors.affiliation: Nandha College of Pharmacy, Erode, Tamilnadu, India. vishalgulecha@rediffmail.com
authors.forename: Vishal
authors.initials: V
authors.lastname: Gulecha
authors.forename: Thangavel
authors.initials: T
authors.lastname: Sivakuma
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000494:pharmacology*; D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D030681:Ficus / Q000737:chemistry*; D006801:Humans; D009369:Neoplasms / Q000378:metabolism; D010936:Plant Extracts / Q000494:pharmacology*; D031304:Tephrosia / Q000737:chemistry*; D014343:Trypan Blue / Q000378:metabolism
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D010936:Plant Extracts; D014343:Trypan Blue