title: Lithium-induced sinus node dysfunction at therapeutic serum levels.
abstract: Lithium-induced cardiotoxicity, though rare at therapeutic levels, has been reported frequently in overdoses. We report a patient who developed sinus bradycardia while being treated with lithium carbonate even though the serum lithium levels were within the therapeutic range. It reversed following withdrawal of lithium and did not reappear with subsequent treatment with valproate.
authors.affiliation: Department of Psychiatry, Pandit Jawaharlal Nehru Medical College, Raipur, Chhattisgarh, India. singhlokesh123@gmail.com
authors.forename: L K
authors.initials: LK
authors.lastname: Singh
authors.forename: S K
authors.initials: SK
authors.lastname: Praharaj
authors.forename: S K
authors.initials: SK
authors.lastname: Munda
authors.forename: C R J
authors.initials: CR
authors.lastname: Khess
mesh_terms: D000328:Adult; D018692:Antimanic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D008094:Lithium / Q000097:blood*; D018020:Lithium Compounds / Q000009:adverse effects* / Q000627:therapeutic use; D008297:Male; D012804:Sick Sinus Syndrome / Q000139:chemically induced*; D013431:Sulfates / Q000009:adverse effects* / Q000627:therapeutic use
chemical_list: D018692:Antimanic Agents; D018020:Lithium Compounds; D013431:Sulfates; C054097:lithium sulfate; D008094:Lithium