title: [Cholesterol-degrading by Lactobacillus plantarum LpT1 and LpT2 in vitro].
abstract: OBJECTIVE
  To explore the mechanism of cholesterol-degrading by Lactobacillus plantarum LpT1 and LpT2 in vitro.
  
  
  METHODS
  After Lactobacillus plantarum LpT1 and LpT2 being inoculated and cultured in the medium MRS, MRS +CH, MRS + CH + S and MRS + CH + N, the cholesterol content in supernatant, deposit and cells, and the total cholesterol content before and after inoculation were determined and compared to primarily predict the mechanism of cholesterol-degrading by L. plantarum.
  
  
  RESULTS
  The mechanism of cholesterol- degrading by L. plantarum LpT1 and LpT2 in vitro involved in metabolic and non-metabolic pathway. Non-metabolic pathway was related to co-precipitation and cell absorption. Metabolic pathway was due to the production of the special enzymes during the growth of L. plantarum which made the cholesterol degrade to be other materials and caused its content reduction.
  
  
  CONCLUSIONS
  L. plantarum has shown its ability to degrade cholesterol in vitro.
authors.affiliation: College of Food Science and Biotechnology, Zhejiang Gongshang University, Hangzhou 310035, China. yup9202@yahoo.com.cn
authors.forename: Ping
authors.initials: P
authors.lastname: Yu
authors.forename: Haisen
authors.initials: H
authors.lastname: Sun
authors.forename: Jianrong
authors.initials: J
authors.lastname: Li
authors.forename: Xiaohui
authors.initials: X
authors.lastname: Wang
authors.forename: Haixia
authors.initials: H
authors.lastname: Lu
mesh_terms: D001426:Bacterial Proteins / Q000235:genetics; D002784:Cholesterol / Q000378:metabolism*; D003470:Culture Media / Q000378:metabolism; D048191:Lactiplantibacillus plantarum / Q000201:enzymology / Q000235:genetics / Q000378:metabolism*
chemical_list: D001426:Bacterial Proteins; D003470:Culture Media; D002784:Cholesterol