title: Multi-endpoint toxicities on Chinese rare minnow (Gobiocypris rarus) fed with different diets.
abstract: To compare the effects of three diets, rare minnow was fed with three diets from 30 dph to mature period. The activities of EROD, PROD, SOD and GST were measured in the WBHs as well as Vtg and TBARS concentrations at 60 dph. The rest fish were fed until adulthood for breeding studies. The group A served as the control group. It was found that Vtg, GST and EROD were significantly increased in the groups B and C, but SOD, TBARS and PROD levels were significantly increased only in the group C. In the adulthood, Vtg was significantly induced in the males in the group C. In generation F1, inhibition of CAT D activities and decrease of reproductive success were only found in pellet A group, but not in pellet B group. These findings indicate that the selection of diet is extremely important to assure veracity of the experiment results.
authors.affiliation: Institute for Farm Products Processing and Nuclear-Agricultural Technology, Hubei Academy of Agricultural Sciences, Hubei Innovation Center of Agricultural Science and Technology, 8# Nanhu YaoYuan Road, Wuhan 430064, China.
authors.forename: Tao
authors.initials: T
authors.lastname: Liao
authors.forename: Fangxing
authors.initials: F
authors.lastname: Yang
authors.forename: Yang
authors.initials: Y
authors.lastname: Hui
authors.forename: Wei
authors.initials: W
authors.lastname: Cheng
authors.forename: Guangquan
authors.initials: G
authors.lastname: Xiong
authors.forename: Shiwei
authors.initials: S
authors.lastname: Jin
authors.forename: Jianwei
authors.initials: J
authors.lastname: Wang
authors.forename: Ying
authors.initials: Y
authors.lastname: Xu
mesh_terms: D000818:Animals; D015415:Biomarkers; D002402:Cathepsin D / Q000378:metabolism; D002681:China; D003530:Cyprinidae / Q000502:physiology*; D019363:Cytochrome P-450 CYP1A1 / Q000378:metabolism; D019362:Cytochrome P-450 CYP2B1 / Q000378:metabolism; D004032:Diet; D005260:Female; D005298:Fertility / Q000187:drug effects; D005978:Glutathione / Q000378:metabolism; D006128:Growth / Q000187:drug effects; D007202:Indicators and Reagents; D015227:Lipid Peroxidation / Q000187:drug effects; D008297:Male; D012098:Reproduction / Q000187:drug effects; D012741:Sexual Maturation / Q000187:drug effects; D013482:Superoxide Dismutase / Q000378:metabolism; D017392:Thiobarbituric Acid Reactive Substances / Q000378:metabolism; D014817:Vitelline Membrane / Q000187:drug effects; D014874:Water Pollutants, Chemical / Q000633:toxicity*
chemical_list: D015415:Biomarkers; D007202:Indicators and Reagents; D017392:Thiobarbituric Acid Reactive Substances; D014874:Water Pollutants, Chemical; D019363:Cytochrome P-450 CYP1A1; D019362:Cytochrome P-450 CYP2B1; D013482:Superoxide Dismutase; D002402:Cathepsin D; D005978:Glutathione