title: Accuracy and variability of right ventricular volumes and mass assessed by dual-source computed tomography: influence of slice orientation in comparison to magnetic resonance imaging.
abstract: OBJECTIVE
  To evaluate the accuracy and variability of right ventricular (RV) volumes and mass using dual-source computed tomography (DSCT) and the influence of slice orientation in comparison to cardiac magnetic resonance imaging (CMR).
  
  
  METHODS
  In 33 patients undergoing cardiac DSCT and CMR, RV parameters were calculated using the short-axis (DSCT, CMR) and axial orientation (DSCT). Intra- and interobserver variability were assessed by Bland-Altman analysis.
  
  
  RESULTS
  Short-axis orientation: RV parameters of the two techniques were not statistically different. Axial orientation: RV volumes and mass were significantly overestimated compared with short-axis parameters whereas EF was similar. The short-axis approach resulted in low variability, although the axial orientation had the least amount of intra- and interobserver variability.
  
  
  CONCLUSIONS
  RV parameters can be more accurately assessed by DSCT compared with CMR using short-axis slice orientation. RV volumes and mass are significantly higher using axial compared with short-axis slices, whereas EF is unaffected. RV parameters derived from both approaches yield high reproducibility.
authors.affiliation: Department of Cardiology and Angiology, Elisabeth Hospital Essen, Essen, Germany. Christoph.Jensen@duke.edu
authors.forename: Christoph J
authors.initials: CJ
authors.lastname: Jensen
authors.forename: Alexander
authors.initials: A
authors.lastname: Wolf
authors.forename: Holger C
authors.initials: HC
authors.lastname: Eberle
authors.forename: Michael
authors.initials: M
authors.lastname: Forsting
authors.forename: Kai
authors.initials: K
authors.lastname: Nassenstein
authors.forename: Thomas C
authors.initials: TC
authors.lastname: Lauenstein
authors.forename: Georg V
authors.initials: GV
authors.lastname: Sabin
authors.forename: Oliver
authors.initials: O
authors.lastname: Bruder
authors.forename: Thomas
authors.initials: T
authors.lastname: Schlosser
mesh_terms: D000465:Algorithms; D015331:Cohort Studies; D003430:Cross-Sectional Studies; D005260:Female; D006352:Heart Ventricles / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D008875:Middle Aged; D015588:Observer Variation; D009929:Organ Size; D015203:Reproducibility of Results; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed / Q000379:methods; D018497:Ventricular Dysfunction, Right / Q000000981:diagnostic imaging* / Q000453:epidemiology / Q000473:pathology*