title: Primary central nervous system mucosa-associated lymphoid tissue lymphoma--case report.
abstract: A 55-year-old woman presented with an extremely rare primary central nervous system mucosa-associated lymphoid tissue (MALT) lymphoma manifesting as seizure and was subsequently diagnosed with dural MALT lymphoma in the cranium. Magnetic resonance imaging revealed a left frontal dural mass with peritumoral edema. Histological examination of the dural mass confirmed MALT lymphoma and revealed infiltration of small cells with irregular nuclear borders and expression of a B cell marker (CD20) but absence of CD5, CD10, CD23, and cyclinD1. Reactive T-cell infiltration was also seen. Subsequently, local irradiation (40 Gy/20 fractions) was performed. Magnetic resonance imaging showed complete remission just after irradiation was completed. There was no evidence of systemic MALT lymphoma. There has been no recurrence for 3 years without additional therapy.
authors.affiliation: Department of Neurosurgery, Graduate School of Medicine, Hokkaido University, Sapporo, Hokkaido, Japan. kamoshima2002@yahoo.co.jp
authors.forename: Yuuta
authors.initials: Y
authors.lastname: Kamoshima
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Sawamura
authors.forename: Taku
authors.initials: T
authors.lastname: Sugiyama
authors.forename: Shigeru
authors.initials: S
authors.lastname: Yamaguchi
authors.forename: Kiyohiro
authors.initials: K
authors.lastname: Houkin
authors.forename: Kanako
authors.initials: K
authors.lastname: Kubota
mesh_terms: D004388:Dura Mater / Q000473:pathology; D005260:Female; D005625:Frontal Lobe / Q000473:pathology; D006801:Humans; D018442:Lymphoma, B-Cell, Marginal Zone / Q000175:diagnosis / Q000473:pathology* / Q000532:radiotherapy*; D008577:Meningeal Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000532:radiotherapy*; D008579:Meningioma / Q000175:diagnosis / Q000473:pathology / Q000532:radiotherapy; D008875:Middle Aged