title: Rubidium-82 cardiac positron emission tomography imaging: an overview for the general cardiologist.
abstract: Cardiac positron emission tomography (PET) imaging has been used for more than 3 decades to study myocardial perfusion and metabolism, but for a majority of those years, confined to large academic and research centers with access to a cyclotron. With the advent of the generator-produced PET radionuclide Rubidium-82, PET myocardial perfusion imaging has become far more accessible in daily practice, and is backed by a strong evidence-base for the diagnosis and prognosis of coronary artery disease and myocardial viability. Intended to describe basic principles for the general cardiologist, this review highlights the role of Rb-82 in PET myocardial perfusion imaging and provides an overview of its properties, its diagnostic accuracy for diagnosing coronary artery disease and myocardial viability, and some unique applications.
authors.affiliation: Henry Ford Hospital, Heart and Vascular Institute, Department of Medicine, Detroit, MI, USA.
authors.forename: Ritesh
authors.initials: R
authors.lastname: Dhar
authors.forename: Karthikeyan
authors.initials: K
authors.lastname: Ananthasubramaniam
mesh_terms: D003324:Coronary Artery Disease / Q000000981:diagnostic imaging*; D006321:Heart / Q000502:physiology; D006801:Humans; D055414:Myocardial Perfusion Imaging; D049268:Positron-Emission Tomography; D012414:Rubidium Radioisotopes; D012507:Sarcoidosis / Q000000981:diagnostic imaging; D014022:Tissue Survival
chemical_list: D012414:Rubidium Radioisotopes