title: Isolated splenic peliosis presenting with giant splenomegaly and severe coagulopathy.
abstract: We herein describe a case of successful surgical treatment of isolated splenic peliosis presenting with giant splenomegaly and severe coagulopathy. Pathological features of the spleen included multinodular, blood-filled, cyst-like lesions distributed throughout the whole organ. The pathogenesis of isolated splenic peliosis is controversial, and no definitive disease mechanism has been reported. To our knowledge, this is the first report in English of a case like this.
authors.affiliation: Department of Surgery, Tokyo Metropolitan Tama Medical Hospital, Fuchu, Tokyo, 183-8524, Japan. kensuke_adachi@tmhp.jp
authors.forename: Kensuke
authors.initials: K
authors.lastname: Adachi
authors.forename: Mitsuhito
authors.initials: M
authors.lastname: Ui
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Nojima
authors.forename: Yukari
authors.initials: Y
authors.lastname: Takada
authors.forename: Kazuaki
authors.initials: K
authors.lastname: Enatsu
mesh_terms: D000686:Amyloidosis / Q000175:diagnosis / Q000209:etiology; D015415:Biomarkers / Q000097:blood; D003560:Cysts / Q000000981:diagnostic imaging / Q000601:surgery; D004211:Disseminated Intravascular Coagulation / Q000097:blood / Q000209:etiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009929:Organ Size; D011693:Purpura / Q000209:etiology; D012720:Severity of Illness Index; D013154:Spleen / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D013156:Splenectomy; D013158:Splenic Diseases / Q000097:blood / Q000150:complications* / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D013163:Splenomegaly / Q000097:blood / Q000209:etiology*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D015415:Biomarkers