title: Bilateral redundancy gain and callosal integrity in a man with callosal lipoma: a diffusion-tensor imaging study.
abstract: We investigated whether abnormalities in the structural organization of the corpus callosum in the presence of curvilinear lipoma are associated with increased facilitation of response time to bilateral stimuli, an effect known as the redundancy gain (RG). A patient (A.J.) with a curvilinear lipoma of the corpus callosum, his genetically-identical twin, and age-matched control participants made speeded responses to luminant stimuli. Structural organization of callosal regions was assessed with diffusion-tensor imaging. A.J. was found to have reduced structural integrity in the splenium of the corpus callosum and produced a large RG suggestive of neural summation.
authors.affiliation: School of Psychology, University of Plymouth, Plymouth, Devon PL4 8AA, UK. matt.roser@plymouth.ac.uk
authors.forename: Matthew E
authors.initials: ME
authors.lastname: Roser
authors.forename: Michael C
authors.initials: MC
authors.lastname: Corballis
authors.forename: Ashok
authors.initials: A
authors.lastname: Jansari
authors.forename: Jon
authors.initials: J
authors.lastname: Fulford
authors.forename: Abdelmalek
authors.initials: A
authors.lastname: Benattayallah
authors.forename: William M
authors.initials: WM
authors.lastname: Adams
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D001932:Brain Neoplasms / Q000175:diagnosis* / Q000503:physiopathology*; D016022:Case-Control Studies; D003337:Corpus Callosum / Q000473:pathology* / Q000503:physiopathology; D056324:Diffusion Tensor Imaging / Q000379:methods; D005260:Female; D007839:Functional Laterality; D006801:Humans; D021621:Imaging, Three-Dimensional; D008067:Lipoma / Q000175:diagnosis* / Q000503:physiopathology*; D008297:Male; D010775:Photic Stimulation; D011597:Psychomotor Performance; D011930:Reaction Time