title: [Study of human papillomavirus in biopsy tissue specimens of esophageal carcinomas in Linzhou city].
abstract: OBJECTIVE
  To investigate the prevalence of human papillomavirus (HPV), particularly of high-risk HPV in biopsy tissue specimens of esophageal carcinomas in Linzhou city.
  
  
  METHODS
  General nested primer sets were used to detected the whole HPV genotypes, following by HPV16 and 18 type specific PCR for the HPV16 and 18 detection respectively.
  
  
  RESULTS
  All 18 biopsy samples were HPV positive, and HPV 16 was detected in 13 of the 18 samples, HPV 18 was detected in 4 of the 18 samples.
  
  
  CONCLUSIONS
  The high rate of HPV in the esophageal carcinoma samples suggested that HPV infection may be an important etiologic factor in the development of esophageal cancer in Linzhou city.
authors.affiliation: Luohe Medical College, Henan 462002, China.
authors.forename: Ming-chen
authors.initials: MC
authors.lastname: Cui
authors.forename: Ying
authors.initials: Y
authors.lastname: Li
authors.forename: Xin
authors.initials: X
authors.lastname: He
authors.forename: Xiao-li
authors.initials: XL
authors.lastname: Wang
authors.forename: Li-dong
authors.initials: LD
authors.lastname: Wang
authors.forename: Hong-tu
authors.initials: HT
authors.lastname: Liu
mesh_terms: D000328:Adult; D000368:Aged; D001706:Biopsy; D002681:China; D004938:Esophageal Neoplasms / Q000209:etiology / Q000821:virology*; D004947:Esophagus / Q000473:pathology / Q000821:virology; D005260:Female; D005838:Genotype; D052162:Human papillomavirus 16 / Q000302:isolation & purification*; D052161:Human papillomavirus 18 / Q000302:isolation & purification*; D006801:Humans; D008297:Male; D008875:Middle Aged; D027383:Papillomaviridae / Q000235:genetics; D016133:Polymerase Chain Reaction