title: New dermal substitutes.
abstract: The quality of skin wound healing can be improved by the application of scaffolds as skin replacement materials. Although the clinical requirements for the function of such materials are defined, the translation of these requirements into physical and mechanobiological properties of scaffolds is difficult. Natural as well as constructed biological materials and synthetic substitutes are discussed. Furthermore, new techniques such as electrospinning and solid freeform fabrication as well as new types of materials such as self-assembling peptides are reviewed with regard to their potential role in the production of skin substitute materials.
authors.affiliation: Association of Dutch Burn Centers, Beverwijk, The Netherlands.
authors.forename: Vincent C
authors.initials: VC
authors.lastname: van der Veen
authors.forename: Bouke K H L
authors.initials: BK
authors.lastname: Boekema
authors.forename: Magda M W
authors.initials: MM
authors.lastname: Ulrich
authors.forename: Esther
authors.initials: E
authors.lastname: Middelkoop
mesh_terms: D001672:Biocompatible Materials; D006801:Humans; D012867:Skin; D017768:Skin, Artificial / Q000639:trends*; D023822:Tissue Engineering / Q000639:trends; D014945:Wound Healing / Q000502:physiology*
chemical_list: D001672:Biocompatible Materials