title: Self-assembled highly ordered ethane-bridged periodic mesoporous organosilica and its application in HPLC.
abstract: Monodisperse spherical periodic mesoporous organosilicas (PMOs) with ethane integrated in the framework were synthesized and their application as stationary phase for chromatographic separation is demonstrated. The ethane-PMOs were prepared by condensation of 1,2-bis(triethoxysilyl)ethane (BTSE) in basic condition using octadecyltrimethylammonium chloride (C(18)TMACl) as template and ethanol as co-solvent. The morphology and mesoporous structure of ethane-PMOs were controlled under different concentrations of sodium hydroxide (NaOH) and EtOH. The results of scanning electron microscopy (SEM), transmission electron microscopy (TEM), powder X-ray diffraction (XRD), nitrogen sorption measurement, Fourier transform infrared spectroscopy (FT-IR) and elemental analysis showed that ethane-PMOs have spherical morphology, uniform particle distribution, highly ordered pore structure, high surface area and narrow pore-size distribution. The column packed with these materials exhibits good permeability, high chemical stability and good selectivity of mixtures of aromatic hydrocarbons in normal phase high-performance liquid chromatography (HPLC).
authors.affiliation: Department of Pharmaceutical Analysis, China Pharmaceutical University, Nanjing, PR China.
authors.forename: Lili
authors.initials: L
authors.lastname: Huang
authors.forename: Juan
authors.initials: J
authors.lastname: Lu
authors.forename: Bin
authors.initials: B
authors.lastname: Di
authors.forename: Fang
authors.initials: F
authors.lastname: Feng
authors.forename: Mengxiang
authors.initials: M
authors.lastname: Su
authors.forename: Fang
authors.initials: F
authors.lastname: Yan
mesh_terms: D002851:Chromatography, High Pressure Liquid; D004980:Ethane / Q000737:chemistry*; D017646:Organosilicon Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D010316:Particle Size; D016062:Porosity; D013499:Surface Properties
chemical_list: D017646:Organosilicon Compounds; D004980:Ethane