title: Synchronous double primary malignant tumor of the gallbladder and liver: a case report.
abstract: We report a case of synchronous double primary tumor of gallbladder and liver. A 63-year-old male was admitted to the hospital complaining of abdominal discomfort. Enhanced computed tomography of the abdomen showed acute cholecystitis with tiny gallbladder stones and a 2.2 cm size enhanced nodule in the left lobe of the liver. Under the impression of acute cholecystitis with gall bladder stones and hepatocellular carcinoma of the left Liver, the patient underwent a laparotomy. At laparotomy, a mass was palpated on the surface of the neck portion of the gall bladder. Intraoperative frozen diagnosis revealed adenocarcinoma of the gall bladder. The patient was diagnosed as having gall bladder cancer and hepatocellular carcinoma, so extended cholecystectomy with dissection of regional lymph nodes and left hemihepatectomy were performed. Histological examination revealed moderated differentiated adenocarcinoma of gallbladder and hepatocellular carcinoma of liver. To our knowledge, the simultaneous occurrence of primary malignant tumor of the gallbladder and liver has never been published before. The patient is doing well with no evidence of recurrence 17 months after surgery.
authors.affiliation: Department of Surgery, Kangnam Sacred Heart Hospital, Hallym Medical Center, 948-1, Daerim-1Dong, Yeongdeunpo-gu, Seoul 150-950, Korea.
authors.forename: Ji Won
authors.initials: JW
authors.lastname: Kim
authors.forename: Jae Woong
authors.initials: JW
authors.lastname: Han
authors.forename: So Young
authors.initials: SY
authors.lastname: Jung
authors.forename: Jae Pil
authors.initials: JP
authors.lastname: Jung
authors.forename: Jeong Won
authors.initials: JW
authors.lastname: Kim
mesh_terms: D002763:Cholecystectomy / Q000379:methods*; D003937:Diagnosis, Differential; D005500:Follow-Up Studies; D005706:Gallbladder Neoplasms / Q000175:diagnosis* / Q000601:surgery; D006498:Hepatectomy / Q000379:methods*; D006801:Humans; D007813:Laparotomy; D008113:Liver Neoplasms / Q000175:diagnosis* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary; D013997:Time Factors; D014057:Tomography, X-Ray Computed