title: Comprehensive risk reduction in patients with atrial fibrillation: emerging diagnostic and therapeutic options--a report from the 3rd Atrial Fibrillation Competence NETwork/European Heart Rhythm Association consensus conference.
abstract: While management of atrial fibrillation (AF) patients is improved by guideline-conform application of anticoagulant therapy, rate control, rhythm control, and therapy of accompanying heart disease, the morbidity and mortality associated with AF remain unacceptably high. This paper describes the proceedings of the 3rd Atrial Fibrillation NETwork (AFNET)/European Heart Rhythm Association (EHRA) consensus conference that convened over 60 scientists and representatives from industry to jointly discuss emerging therapeutic and diagnostic improvements to achieve better management of AF patients. The paper covers four chapters: (i) risk factors and risk markers for AF; (ii) pathophysiological classification of AF; (iii) relevance of monitored AF duration for AF-related outcomes; and (iv) perspectives and needs for implementing better antithrombotic therapy. Relevant published literature for each section is covered, and suggestions for the improvement of management in each area are put forward. Combined, the propositions formulate a perspective to implement comprehensive management in AF.
authors.affiliation: University Hospital Münster, Münster, Germany. kirchhp@uni-muenster.de
authors.forename: Paulus
authors.initials: P
authors.lastname: Kirchhof
authors.forename: Gregory Y H
authors.initials: GY
authors.lastname: Lip
authors.forename: Isabelle C
authors.initials: IC
authors.lastname: Van Gelder
authors.forename: Jeroen
authors.initials: J
authors.lastname: Bax
authors.forename: Elaine
authors.initials: E
authors.lastname: Hylek
authors.forename: Stefan
authors.initials: S
authors.lastname: Kaab
authors.forename: Ulrich
authors.initials: U
authors.lastname: Schotten
authors.forename: Karl
authors.initials: K
authors.lastname: Wegscheider
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Boriani
authors.forename: Axel
authors.initials: A
authors.lastname: Brandes
authors.forename: Michael
authors.initials: M
authors.lastname: Ezekowitz
authors.forename: Hans
authors.initials: H
authors.lastname: Diener
authors.forename: Laurent
authors.initials: L
authors.lastname: Haegeli
authors.forename: Hein
authors.initials: H
authors.lastname: Heidbuchel
authors.forename: Deirdre
authors.initials: D
authors.lastname: Lane
authors.forename: Luis
authors.initials: L
authors.lastname: Mont
authors.forename: Stephan
authors.initials: S
authors.lastname: Willems
authors.forename: Paul
authors.initials: P
authors.lastname: Dorian
authors.forename: Maria
authors.initials: M
authors.lastname: Aunes-Jansson
authors.forename: Carina
authors.initials: C
authors.lastname: Blomstrom-Lundqvist
authors.forename: Maria
authors.initials: M
authors.lastname: Borentain
authors.forename: Stefanie
authors.initials: S
authors.lastname: Breitenstein
authors.forename: Martina
authors.initials: M
authors.lastname: Brueckmann
authors.forename: Nilo
authors.initials: N
authors.lastname: Cater
authors.forename: Andreas
authors.initials: A
authors.lastname: Clemens
authors.forename: Dobromir
authors.initials: D
authors.lastname: Dobrev
authors.forename: Sergio
authors.initials: S
authors.lastname: Dubner
authors.forename: Nils G
authors.initials: NG
authors.lastname: Edvardsson
authors.forename: Leif
authors.initials: L
authors.lastname: Friberg
authors.forename: Andreas
authors.initials: A
authors.lastname: Goette
authors.forename: Michele
authors.initials: M
authors.lastname: Gulizia
authors.forename: Robert
authors.initials: R
authors.lastname: Hatala
authors.forename: Jenny
authors.initials: J
authors.lastname: Horwood
authors.forename: Lukas
authors.initials: L
authors.lastname: Szumowski
authors.forename: Lukas
authors.initials: L
authors.lastname: Kappenberger
authors.forename: Josef
authors.initials: J
authors.lastname: Kautzner
authors.forename: Angelika
authors.initials: A
authors.lastname: Leute
authors.forename: Trudie
authors.initials: T
authors.lastname: Lobban
authors.forename: Ralf
authors.initials: R
authors.lastname: Meyer
authors.forename: Jay
authors.initials: J
authors.lastname: Millerhagen
authors.forename: John
authors.initials: J
authors.lastname: Morgan
authors.forename: Felix
authors.initials: F
authors.lastname: Muenzel
authors.forename: Michael
authors.initials: M
authors.lastname: Nabauer
authors.forename: Christoph
authors.initials: C
authors.lastname: Baertels
authors.forename: Michael
authors.initials: M
authors.lastname: Oeff
authors.forename: Dieter
authors.initials: D
authors.lastname: Paar
authors.forename: Juergen
authors.initials: J
authors.lastname: Polifka
authors.forename: Ursula
authors.initials: U
authors.lastname: Ravens
authors.forename: Ludger
authors.initials: L
authors.lastname: Rosin
authors.forename: W
authors.initials: W
authors.lastname: Stegink
authors.forename: Gerhard
authors.initials: G
authors.lastname: Steinbeck
authors.forename: Panos
authors.initials: P
authors.lastname: Vardas
authors.forename: Alphons
authors.initials: A
authors.lastname: Vincent
authors.forename: Maureen
authors.initials: M
authors.lastname: Walter
authors.forename: Günter
authors.initials: G
authors.lastname: Breithardt
authors.forename: A John
authors.initials: AJ
authors.lastname: Camm
mesh_terms: D000818:Animals; D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use; D001281:Atrial Fibrillation / Q000175:diagnosis* / Q000188:drug therapy / Q000503:physiopathology / Q000628:therapy*; D015415:Biomarkers / Q000032:analysis; D005260:Female; D005343:Fibrinolytic Agents / Q000627:therapeutic use; D006801:Humans; D008297:Male; D051381:Rats; D040242:Risk Reduction Behavior; D016896:Treatment Outcome
chemical_list: D000889:Anti-Arrhythmia Agents; D015415:Biomarkers; D005343:Fibrinolytic Agents