title: Green tea consumption, abdominal obesity as related factors of lacunar infarction in Korean women.
abstract: OBJECTIVE
  Our purpose was to evaluate interaction of green tea consumption and abdominal obesity as related factors for lacunar infarction in Korean women.
  
  
  METHODS
  A hospital-based, incident case-control study.
  
  
  METHODS
  The Prevention and Managements of Stroke in Women study.
  
  
  METHODS
  Cases (n=233) of first incident lacunar infarction were enrolled and matched by age to stroke-free hospital controls (n=204).
  
  
  METHODS
  The data were collected through face-to-face interviews by well trained research assistants to assess demographic, medical, lifestyle, marital status, religions status, green tea consumptions, family history of stroke, smoking status, alcohol consumption, meat and vegetable intake frequency, and past history of hypertension. Biochemical analysis, fasting blood specimens for lipid, glucose, and cholesterol level were acquired.
  
  
  RESULTS
  Compared with the non green tea consumer and obese women group, only the green tea consumption and non obese women group had a protective effect of lacunar infarction when adjusted for age, and age plus diet factors (OR, 0.23; 95% CI, 0.09, 0.59; OR, 0.21; 95% CI, 0.08, 0.56 respectively), but lost their significance after adjustment for age, diet factors, vascular risk factors and full model included atherogenic index factors (OR, 0.32; 95% CI, 0.09 to 1.01; OR, 0.49; 95% CI, 0.12, 1.89 respectively).
  
  
  CONCLUSIONS
  The interaction of green tea consumption and non obesity have reduced risk of lacunar infarction, but not after adjustment for age, diet factors, vascular risk factors and atherogenic index. Also individually green tea consumption and abdominal obesity have failed to find an independent relationship with lacunar infarction after adjustment by all risk factors. Green tea consumption and green tea consumption with non obese group seemed to have a protective effect for lacunar infarction. In the results of our study, these results still remain controversial, and then we need further and larger study to get at the root of real causal effect of both relationships.
authors.affiliation: Center for Clinical Research and Genomics, Kyung Hee University, Seoul.
authors.forename: S-G
authors.initials: SG
authors.lastname: Ko
authors.forename: H
authors.initials: H
authors.lastname: Go
authors.forename: S
authors.initials: S
authors.lastname: Sun
authors.forename: S
authors.initials: S
authors.lastname: Lee
authors.forename: W
authors.initials: W
authors.lastname: Park
authors.forename: Y
authors.initials: Y
authors.lastname: Choi
authors.forename: Y
authors.initials: Y
authors.lastname: Song
authors.forename: G
authors.initials: G
authors.lastname: Hwang
authors.forename: G
authors.initials: G
authors.lastname: Kim
authors.forename: C
authors.initials: C
authors.lastname: Jeon
authors.forename: J
authors.initials: J
authors.lastname: Park
authors.forename: K
authors.initials: K
authors.lastname: Lee
authors.forename: M
authors.initials: M
authors.lastname: Cha
authors.forename: O
authors.initials: O
authors.lastname: Bang
authors.forename: H
authors.initials: H
authors.lastname: Jung
authors.forename: N
authors.initials: N
authors.lastname: Kim
authors.forename: Y-C
authors.initials: YC
authors.lastname: Shin
mesh_terms: D000368:Aged; D044466:Asian People; D028241:Camellia sinensis; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D007407:Interviews as Topic; D007723:Korea; D008875:Middle Aged; D056128:Obesity, Abdominal / Q000150:complications*; D016017:Odds Ratio; D012307:Risk Factors; D059409:Stroke, Lacunar / Q000209:etiology / Q000517:prevention & control; D013662:Tea
chemical_list: D013662:Tea