title: The role of omega-3 fatty acids contained in olive oil on chronic inflammation.
abstract: Nowadays, people have been eating lots of unhealthy dietary excesses, that make them have chronic inflammatory diseases or known as chronic diseases. Countless millions of people worldwide can not help eating selectively massive quantities of unhealthy foods, until they become sick, often mortality. The omega-6 fatty acids account for the majority of PUFA (Poly Unsaturated Fatty Acids) in the food supply. They are the pre-dominant PUFA in all diets, especially the western diets, which produce pro-inflammatory metabolic products. The persistent antigenic or cytotoxic effects will lead to chronic inflammation. Olive tree is native to the Mediterranean basin and parts of Asia Minor. Its compression-extracted oil from the fruit has a wide range of therapeutic and culinary applications. It had been used as aphrodisiacs, emollients, laxatives, nutritives, sedatives, and tonics. In the later part of the 20th century, several studies had revealed that the olives in the Mediteranian diet is linked to a reduced incidence of degenerative diseases. It is one of phytomedicine which has omega-3 fatty acid as its constituent, may inhibit inflammation composing chronic inflammatory process in many chronic diseases, such as coronary artery disease, rheumatoid arthritis, hypertension, and even cancer.
authors.affiliation: Division of Allergy and Clinical Immunology, Department of Internal Medicine, Sam Ratulangi University School of Medicine/Prof.Dr.RD Kandou General Hospital-Sitti Maryam Islamic Hospital, Manado, North Sulawesi, Indonesia. wadiswas@yahoo.com
authors.lastname: Wardhana
authors.forename: Eko S
authors.initials: ES
authors.lastname: Surachmanto
authors.forename: E A
authors.initials: EA
authors.lastname: Datau
mesh_terms: D002908:Chronic Disease; D004032:Diet; D015525:Fatty Acids, Omega-3 / Q000627:therapeutic use*; D043371:Fatty Acids, Omega-6 / Q000009:adverse effects; D006801:Humans; D007249:Inflammation / Q000188:drug therapy*; D008019:Life Style; D009752:Nutritional Status; D000069463:Olive Oil; D010938:Plant Oils / Q000009:adverse effects / Q000494:pharmacology / Q000627:therapeutic use*
chemical_list: D015525:Fatty Acids, Omega-3; D043371:Fatty Acids, Omega-6; D000069463:Olive Oil; D010938:Plant Oils