title: Subcutaneous myxopapillary ependymal rest: a potential sign of spinal dysraphism.
abstract: Subcutaneous myxopapillary ependymal rests are heterotopias of neuroglial tissue that present in the subcutaneous tissue of the sacrococcygeal region. We report a case which presented as a flesh-colored, pedunculated papule near the gluteal cleft. The presence of a congenital lesion near the midline of the spine should alert the clinician to the possibility of spinal dysraphism and necessitates imaging before biopsy. Subcutaneous myxopapillary rests are benign but must be distinguished from their histologic mimic, subcutaneous myxopapillary ependymomas, which are low-grade tumors with metastatic potential.
authors.affiliation: Departments of Dermatology and Cutaneous Pathology, Cleveland Clinic, Cleveland, Ohio.
authors.forename: Laura M
authors.initials: LM
authors.lastname: Burdick
authors.affiliation: Departments of Dermatology and Cutaneous Pathology, Cleveland Clinic, Cleveland, Ohio.
authors.forename: Wilma
authors.initials: W
authors.lastname: Bergfeld
authors.affiliation: Departments of Dermatology and Cutaneous Pathology, Cleveland Clinic, Cleveland, Ohio.
authors.forename: Najwa
authors.initials: N
authors.lastname: Somani
authors.affiliation: Departments of Dermatology and Cutaneous Pathology, Cleveland Clinic, Cleveland, Ohio.
authors.forename: Melissa
authors.initials: M
authors.lastname: Piliang
mesh_terms: D002828:Choristoma / Q000473:pathology*; D004805:Ependyma / Q000473:pathology*; D004806:Ependymoma / Q000175:diagnosis / Q000473:pathology; D005260:Female; D006801:Humans; D007223:Infant; D012445:Sacrococcygeal Region / Q000473:pathology; D016135:Spinal Dysraphism / Q000473:pathology*; D040521:Subcutaneous Tissue / Q000473:pathology