title: Effects of corneal thickness and axial length on intraocular pressure and ocular pulse amplitude before and after cataract surgery.
abstract: OBJECTIVE
  To investigate the relationship between the biophysical properties of the cornea and eye on the intraocular pressure (IOP) and ocular pulse amplitude (OPA) before and after cataract surgery.
  
  
  METHODS
  Intervention study.
  
  
  METHODS
  The left eyes of 311 patients.
  
  
  METHODS
  The left eyes of 338 patients undergoing cataract surgery without other eye pathology were studied. IOP and OPA were recorded by dynamic contour tonometry (DCT) 1 week before and 14 weeks after cataract surgery. The axial length, corneal curvature, central corneal thickness, anterior chamber depth, and anterior chamber angle were measured 1 week before cataract surgery. Multiple regression analyses of these factors to the preoperative OPA were performed. The difference between the pre- and postoperative IOP and OPA were investigated by paired t tests.
  
  
  RESULTS
  Three hundred and eleven of 338 eyes were analyzed. The preoperative OPA was negatively correlated with axial length (β = -0.24, p < 0.0001) and positively correlated with the preoperative IOP (β = 0.13, p < 0.0001). The average OPA was significantly decreased after cataract surgery (p < 0.0001). The mean change in postoperative OPA was -0.45 ± 0.63 mm Hg (95% CI -0.52 to -0.38 mm Hg).
  
  
  CONCLUSIONS
  The preoperative OPA was negatively correlated with axial length as reported. A significant decrease in OPA was observed after the cataract surgery.
authors.affiliation: Department of Ophthalmology, Tsukazaki Hospital, Himeji, 68-1 Waku, Aboshi-ku, Himeji-City, Hyogo 671-1227, Japan. H.Tabuchi@tsukazaki-eye.net
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Tabuchi
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Kiuchi
authors.forename: Hideharu
authors.initials: H
authors.lastname: Ohsugi
authors.forename: Shunsuke
authors.initials: S
authors.lastname: Nakakura
authors.forename: Zaigen
authors.initials: Z
authors.lastname: Han
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000867:Anterior Chamber / Q000033:anatomy & histology / Q000502:physiology; D001703:Biophysics; D002387:Cataract Extraction; D003315:Cornea / Q000033:anatomy & histology* / Q000502:physiology*; D005260:Female; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D011184:Postoperative Period; D057234:Preoperative Period; D011446:Prospective Studies; D011673:Pulsatile Flow / Q000502:physiology*; D014065:Tonometry, Ocular; D014129:Trabecular Meshwork / Q000033:anatomy & histology / Q000502:physiology