title: The molecular biology of inflammatory bowel diseases.
abstract: IBDs (inflammatory bowel diseases) are a group of diseases affecting the gastrointestinal tract. The diseases are multifactorial and cover genetic aspects: susceptibility genes, innate and adaptive responses to inflammation, and structure and efficacy of the mucosal protective barrier. Animal models of IBD have been developed to gain further knowledge of the disease mechanisms. These topics form an overlapping background to enable an improved understanding of the molecular features of these diseases. A series of articles is presented based on the topics covered at the Biochemical Society Focused Meeting The Molecular Biology of Inflammatory Bowel Diseases.
authors.affiliation: Mucin Research Group, School of Clinical Sciences, Bristol Royal Infirmary, Level 7, Marlborough Street, Bristol BS2 8HW, UK. tony.corfield@bristol.ac.uk
authors.forename: Anthony P
authors.initials: AP
authors.lastname: Corfield
authors.forename: Heather M
authors.initials: HM
authors.lastname: Wallace
authors.forename: Chris S J
authors.initials: CS
authors.lastname: Probert
mesh_terms: D000818:Animals; D004032:Diet; D041981:Gastrointestinal Tract / Q000382:microbiology / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000209:etiology / Q000235:genetics* / Q000382:microbiology / Q000503:physiopathology; D008967:Molecular Biology