title: [Experimental quality assessment of APTT-control reagent kits in the study of plasma with varying Factor VIII activity].
abstract: An investigation into activated partial thromboplastin time (APTT) in the plasma samples with varying Factor VIII activities has determined the following parameters of the quality of APTT-control reagent kits: coefficient of variation, linearity, sensitivity, and detection. The kit is shown to meet GOST P 51352-99 requirements. The determination of the validity coefficient of approximation has proven a directly proportional functional relationship of the APTT values to the Factor VIII activity in the bilogarithmic coordinate system. The kit may be used to diagnose hemophilia A and Willebrand disease.
authors.forename: N N
authors.initials: NN
authors.lastname: Staritsyna
authors.forename: A I
authors.initials: AI
authors.lastname: Shanskaia
authors.forename: L P
authors.initials: LP
authors.lastname: Papaian
authors.forename: R P
authors.initials: RP
authors.lastname: Ivanova
mesh_terms: D005169:Factor VIII / Q000235:genetics / Q000378:metabolism*; D006467:Hemophilia A / Q000175:diagnosis* / Q000235:genetics; D006801:Humans; D010314:Partial Thromboplastin Time / Q000379:methods / Q000592:standards*; D010949:Plasma / Q000378:metabolism*; D011786:Quality Control; D011933:Reagent Kits, Diagnostic / Q000706:statistics & numerical data; D012015:Reference Standards; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014842:von Willebrand Diseases / Q000175:diagnosis* / Q000235:genetics
chemical_list: D011933:Reagent Kits, Diagnostic; D005169:Factor VIII