title: Invited commentary.
authors.affiliation: Division of Cardiothoracic and Vascular Anesthesia, University of Pennsylvania, 3400 Spruce St, Dulles 680, Philadelphia, PA 19104-4283, USA.
authors.forename: Scott A
authors.initials: SA
authors.lastname: Falk
authors.forename: Albert T
authors.initials: AT
authors.lastname: Cheung
mesh_terms: D055371:Acute Lung Injury / Q000401:mortality; D001803:Blood Transfusion / Q000706:statistics & numerical data; D005500:Follow-Up Studies; D006331:Heart Diseases / Q000401:mortality / Q000601:surgery*; D006333:Heart Failure / Q000401:mortality; D017052:Hospital Mortality; D006801:Humans; D053208:Kaplan-Meier Estimate; D016015:Logistic Models; D018447:Medical Futility; D010949:Plasma; D011183:Postoperative Complications / Q000401:mortality* / Q000628:therapy; D016016:Proportional Hazards Models; D012131:Respiratory Insufficiency / Q000401:mortality* / Q000628:therapy; D012189:Retrospective Studies; D012307:Risk Factors; D014139:Tracheostomy / Q000401:mortality*; D065227:Transfusion Reaction; D015300:Ventilator Weaning