title: [Melanin of Laetiporus sulphureus (Bull.: Fr.) Murr sterile form].
abstract: Melanin complex was isolated from mycelium of the basidiomycete Laetiporus sulphumreus (Bull.: Fr.) Murr (with a yield of 2.49% of the fresh weight). UV and IR spectroscopies, gel chromatography, and alkaline cleavage assay demonstrated that the isolated melanin was heterogeneous and belonged to the dihydronaphthalene type. 13C-NMR data suggested that aromatic fragments were dominant in the melanin structure. In vitro study of the antioxidant action demonstrated that the L. sulphureus melanin displayed a radical-scavenging activity and the ability to inactivate hydrogen peroxide and nitrogen(II) oxide molecules and to chelate iron(II) ions.
authors.forename: D N
authors.initials: DN
authors.lastname: Olennikov
authors.forename: S V
authors.initials: SV
authors.lastname: Agafonova
authors.forename: A V
authors.initials: AV
authors.lastname: Stolbikova
authors.forename: A V
authors.initials: AV
authors.lastname: Rokhin
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000737:chemistry / Q000302:isolation & purification / Q000378:metabolism; D001487:Basidiomycota / Q000254:growth & development / Q000378:metabolism*; D002850:Chromatography, Gel; D002855:Chromatography, Thin Layer; D005296:Ferrous Compounds / Q000378:metabolism; D006861:Hydrogen Peroxide / Q000378:metabolism; D007246:Infertility; D007501:Iron / Q000378:metabolism; D009682:Magnetic Resonance Spectroscopy; D008543:Melanins / Q000096:biosynthesis / Q000737:chemistry / Q000302:isolation & purification; D009281:Naphthalenes / Q000737:chemistry / Q000302:isolation & purification / Q000378:metabolism; D009589:Nitrogen Oxides / Q000378:metabolism; D051381:Rats; D017208:Rats, Wistar; D013057:Spectrum Analysis
chemical_list: D000975:Antioxidants; D005296:Ferrous Compounds; D008543:Melanins; D009281:Naphthalenes; D009589:Nitrogen Oxides; D006861:Hydrogen Peroxide; D007501:Iron