title: Antiestrogen therapy in recurrent ovarian cancer resulting in 28 months of stable disease: a case report and review of the literature.
abstract: Hormonal therapy for adjuvant treatment of ovarian cancer may provide a low toxicity option in some patients with refractory disease. A 53 year-old patient with stage IIIC papillary serous ovarian cancer previously treated with multiple chemotherapy regimens with platinum-resistant disease was treated with antiestrogen therapy for 28 months before requiring reinstitution of cytotoxic chemotherapy. Hormonal therapy may be effective in a subset of epithelial ovarian cancer patients with endocrine sensitivity and should be considered in the treatment of platinum-resistant patients.
authors.affiliation: University of Minnesota Medical Center, Division of Gynecologic Oncology, Minneapolis, MN, USA.
authors.forename: Rajul
authors.initials: R
authors.lastname: Kothari
authors.forename: Peter
authors.initials: P
authors.lastname: Argenta
authors.forename: Jeffrey
authors.initials: J
authors.lastname: Fowler
authors.forename: Jori
authors.initials: J
authors.lastname: Carter
authors.forename: William
authors.initials: W
authors.lastname: Shimp