title: Ferritin level at diagnosis is not correlated with poorer survival in non RBC transfusion dependent lower risk de novo MDS.
abstract: We evaluated the prognostic value of serum ferritin (SF) level at diagnosis in 318 newly diagnosed IPSS low and int 1 (lower) risk MDS patients included in the French MDS registry, who did not require RBC transfusions and had baseline SF level determination. Increased baseline SF level (>300 ng/ml) was correlated with male gender, more pronounced anaemia, and diagnosis of RARS but had no negative impact on progression to AML or survival.
authors.affiliation: Hôpital Cochin Assistance Publique des Hôpitaux de Paris (AP-HP), Paris V, France. sophie.park@cch.aphp.fr
authors.forename: S
authors.initials: S
authors.lastname: Park
authors.forename: R
authors.initials: R
authors.lastname: Sapena
authors.forename: C
authors.initials: C
authors.lastname: Kelaidi
authors.forename: D
authors.initials: D
authors.lastname: Vassilieff
authors.forename: D
authors.initials: D
authors.lastname: Bordessoule
authors.forename: A
authors.initials: A
authors.lastname: Stamatoullas
authors.forename: S
authors.initials: S
authors.lastname: Cheze
authors.forename: O
authors.initials: O
authors.lastname: Beyne-Rauzy
authors.forename: N
authors.initials: N
authors.lastname: Vey
authors.forename: C
authors.initials: C
authors.lastname: Rose
authors.forename: A
authors.initials: A
authors.lastname: Guerci
authors.forename: Shanti
authors.initials: S
authors.lastname: Natarajan-Amé
authors.forename: Gérard
authors.initials: G
authors.lastname: Tertian
authors.forename: B
authors.initials: B
authors.lastname: Slama
authors.forename: P
authors.initials: P
authors.lastname: Fenaux
authors.forename: F
authors.initials: F
authors.lastname: Dreyfus
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001803:Blood Transfusion; D005260:Female; D005293:Ferritins / Q000378:metabolism*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009190:Myelodysplastic Syndromes / Q000097:blood / Q000175:diagnosis* / Q000401:mortality*; D011379:Prognosis; D012307:Risk Factors; D015996:Survival Rate
chemical_list: D005293:Ferritins