title: Application of chicken egg yolk immunoglobulins in the control of terrestrial and aquatic animal diseases: a review.
abstract: Oral administration of chicken egg yolk immunoglobulin (IgY) has attracted considerable attention as a means of controlling infectious diseases of bacterial and viral origin. Oral administration of IgY possesses many advantages compared with mammalian IgG including cost-effectiveness, convenience and high yield. This review presents an overview of the potential to use IgY immunotherapy for the prevention and treatment of terrestrial and aquatic animal diseases and speculates on the future of IgY technology. Included are a review of the potential application of IgY for the treatment of livestock diseases such as mastitis and diarrhea, poultry diseases such as Salmonella, Campylobacteriosis, infectious bursal disease and Newcastle disease, as well as aquatic diseases like shrimp white spot syndrome virus, Yersina ruckeri and Edwardsiella tarda. Some potential obstacles to the adoption of IgY technology are also discussed.
authors.affiliation: School of Life Science and Technology, Dalian University of Technology, Dalian 116024, China.
authors.forename: Yongping
authors.initials: Y
authors.lastname: Xu
authors.forename: Xiaoyu
authors.initials: X
authors.lastname: Li
authors.forename: Liji
authors.initials: L
authors.lastname: Jin
authors.forename: Yuhong
authors.initials: Y
authors.lastname: Zhen
authors.forename: Yanan
authors.initials: Y
authors.lastname: Lu
authors.forename: Shuying
authors.initials: S
authors.lastname: Li
authors.forename: Jiansong
authors.initials: J
authors.lastname: You
authors.forename: Linhui
authors.initials: L
authors.lastname: Wang
mesh_terms: D000284:Administration, Oral; D000820:Animal Diseases / Q000188:drug therapy* / Q000276:immunology / Q000517:prevention & control; D000818:Animals; D002645:Chickens; D003141:Communicable Diseases / Q000188:drug therapy* / Q000276:immunology; D004530:Egg Yolk; D007116:Immunization, Passive; D007136:Immunoglobulins / Q000276:immunology / Q000494:pharmacology*; D058751:Livestock; D033561:Penaeidae
chemical_list: C016512:IgY; D007136:Immunoglobulins