title: Determination of bisphenol A, 4-n-nonylphenol, and 4-tert-octylphenol by temperature-controlled ionic liquid dispersive liquid-phase microextraction combined with high performance liquid chromatography-fluorescence detector.
abstract: Present study described a simple, sensitive, and viable method for the determination of bisphenol A, 4-n-nonylphenol and 4-tert-octylphenol in water samples using temperature-controlled ionic liquid dispersive liquid-phase microextraction coupled to high performance liquid chromatography-fluorescence detector. In this experiment, 1-octyl-3-methylimidazolium hexafluorophosphate ([C(8)MIM][PF(6)]) was used as the extraction solvent, and bisphenol A, 4-n-nonylphenol and 4-tert-octylphenol were selected as the model analytes. Parameters affecting the extraction efficiency such as the volume of [C(8)MIM][PF(6)], dissolving temperature, extraction time, sample pH, centrifuging time and salting-out effect have been investigated in detail. Under the optimized conditions, good linear relationship was found in the concentration range of 1.0-100 μg L(-1) for BPA, 1.5-150 μg L(-1) for 4-NP, and 3-300 μg L(-1) for 4-OP, respectively. Limits of detection (LOD, S/N=3) were in the range of 0.23-0.48 μg L(-1). Intra day and inter day precisions (RSDs, n=6) were in the range of 4.6-5.5% and 8.5-13.3%, respectively. This method has been also successfully applied to analyze the real water samples at two different spiked concentrations and excellent results were obtained.
authors.affiliation: Henan Key Laboratory for Environmental Pollution Control, Ministry of Education, School of Chemistry and Environmental Sciences, Henan Normal University, Xinxiang, China. zhouqx@cup.edu.cn
authors.forename: Qingxiang
authors.initials: Q
authors.lastname: Zhou
authors.forename: Yuanyuan
authors.initials: Y
authors.lastname: Gao
authors.forename: Guohong
authors.initials: G
authors.lastname: Xie
mesh_terms: D001559:Benzhydryl Compounds; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D004784:Environmental Monitoring / Q000379:methods; D005618:Fresh Water / Q000032:analysis / Q000737:chemistry; D006801:Humans; D007093:Imidazoles / Q000737:chemistry; D052578:Ionic Liquids / Q000737:chemistry; D059627:Liquid Phase Microextraction / Q000379:methods*; D010636:Phenols / Q000032:analysis*; D015203:Reproducibility of Results; D045483:Rivers / Q000737:chemistry; D012722:Sewage / Q000032:analysis / Q000737:chemistry; D012997:Solvents / Q000737:chemistry; D013050:Spectrometry, Fluorescence / Q000379:methods; D013696:Temperature; D014874:Water Pollutants, Chemical / Q000032:analysis*; D000098826:Bisphenol A Compounds
chemical_list: D001559:Benzhydryl Compounds; D007093:Imidazoles; D052578:Ionic Liquids; D010636:Phenols; D012722:Sewage; D012997:Solvents; D014874:Water Pollutants, Chemical; C446740:1-octyl-3-methylimidazolium hexafluorophosphate; C041594:4-nonylphenol; C105260:4-tert-octylphenol; C006780:bisphenol A; D000098826:Bisphenol A Compounds