title: Complex partial cluster seizures in cats with orofacial involvement.
abstract: Seventeen cats were presented with acute onset of complex partial seizures with orofacial involvement (salivation, facial twitching, lip smacking, chewing, licking or swallowing), motor arrest (motionless starring) and behavioural changes. In 11 cats hippocampal necrosis (HN) was confirmed by histopathology. In a further six cats hippocampal changes were suggested by magnetic resonance imaging. The mean monitoring time of eight cats which were not euthanased in the acute phase of the disease, was 408 days (60-908): four cats are still alive. In all surviving cases, the owners reported a good quality of life. We conclude that an acute cluster of complex partial seizures with orofacial involvement are often associated with HN and that HN is not necessarily a fatal condition. Supportive and antiepileptic therapy can result in remission. The long-term outcome can be good to excellent; therefore, euthanasia should be avoided in the acute phase of the signs.
authors.affiliation: Clinic for Internal Medicine and Infectious Diseases, Vienna, Austria. akos.pakozdy@vetmeduni.ac.at
authors.forename: Akos
authors.initials: A
authors.lastname: Pakozdy
authors.forename: Andrea
authors.initials: A
authors.lastname: Gruber
authors.forename: Sibylle
authors.initials: S
authors.lastname: Kneissl
authors.forename: Michael
authors.initials: M
authors.lastname: Leschnik
authors.forename: Peter
authors.initials: P
authors.lastname: Halasz
authors.forename: Johann G
authors.initials: JG
authors.lastname: Thalhammer
mesh_terms: D000818:Animals; D000927:Anticonvulsants / Q000627:therapeutic use; D001522:Behavior, Animal; D002371:Cat Diseases / Q000188:drug therapy / Q000473:pathology / Q000503:physiopathology*; D002415:Cats; D004828:Epilepsies, Partial / Q000473:pathology / Q000503:physiopathology / Q000662:veterinary*; D005152:Facial Muscles; D005260:Female; D006624:Hippocampus / Q000473:pathology; D008279:Magnetic Resonance Imaging / Q000662:veterinary; D008297:Male; D009336:Necrosis; D013035:Spasm / Q000503:physiopathology / Q000662:veterinary
chemical_list: D000927:Anticonvulsants