title: Circulating coxsackievirus A16 identified as recombinant type A human enterovirus, China.
abstract: To determine the relationship of coxsackievirus A16 (CA16) to prototype CA16-G10, we conducted a phylogenetic analysis of circulating CA16 strains in China. Complex recombinant forms of CA16-related viruses involving multiple human enteroviruses, subgroup A (CA4, CA16, and enterovirus 71), are prevalent among patients with hand, foot, and mouth disease.
authors.affiliation: First Hospital of Jilin University, Changchun, People's Republic of China.
authors.forename: Ke
authors.initials: K
authors.lastname: Zhao
authors.forename: Xue
authors.initials: X
authors.lastname: Han
authors.forename: Guanjun
authors.initials: G
authors.lastname: Wang
authors.forename: Wei
authors.initials: W
authors.lastname: Hu
authors.forename: Wenyan
authors.initials: W
authors.lastname: Zhang
authors.forename: Xiao-Fang
authors.initials: XF
authors.lastname: Yu
mesh_terms: D002681:China / Q000453:epidemiology; D029821:Enterovirus A, Human / Q000145:classification / Q000235:genetics*; D004769:Enterovirus Infections / Q000453:epidemiology* / Q000821:virology; D006232:Hand, Foot and Mouth Disease / Q000453:epidemiology* / Q000821:virology; D006801:Humans; D008969:Molecular Sequence Data; D010802:Phylogeny; D011995:Recombination, Genetic; D017422:Sequence Analysis, DNA