title: Larvicidal activity of Tagetes erecta against Aedes aegypti.
abstract: The aim of this study was to evaluate the activity of essential oil from Tagetes erecta against 3rd instars of Aedes aegypti and to determine the amounts of larvicidal thiophenes in all plant tissues. The oil obtained by steam distillation and analyzed by gas chromatography/mass spectrometry showed 14 compounds. The main compounds were piperitone (45.72%), D-limonene (9.67%), and piperitenone (5.89%). The essential oil was active against larvae of Ae. aegypti, with LC50 of 79.78 microg/ml and LC90 of 100.84 microg/ml. The larvicidal thiophene contents were higher in the roots and flowers as demonstrated by high-performance liquid chromatography analysis. Thus, T. erecta constitutes a good source of varied compounds showing larvicidal activity against Ae. aegypti.
authors.affiliation: Laboratory of Natural Products Chemistry, Ceará State University, Campus do Itaperi, Avenida Parajana 1700, CEP 60740-000, Fortaleza, Ceará, Brazil.
authors.forename: Márcia M M
authors.initials: MM
authors.lastname: Marques
authors.forename: Selene M
authors.initials: SM
authors.lastname: Morais
authors.forename: Icaro G P
authors.initials: IG
authors.lastname: Vieira
authors.forename: Mariano G S
authors.initials: MG
authors.lastname: Vieira
authors.forename: Ana
authors.initials: A
authors.lastname: Raquel
authors.forename: A
authors.initials: A
authors.lastname: Silva
authors.forename: Raimundo Rafael
authors.initials: RR
authors.lastname: De Almeida
authors.forename: Maria Izabel F
authors.initials: MI
authors.lastname: Guedes
mesh_terms: D000330:Aedes / Q000187:drug effects; D000818:Animals; D000081005:Cyclohexane Monoterpenes; D053138:Cyclohexenes; D008401:Gas Chromatography-Mass Spectrometry; D007306:Insecticides; D007814:Larva / Q000187:drug effects; D007928:Lethal Dose 50; D000077222:Limonene; D039821:Monoterpenes; D009032:Mosquito Control / Q000379:methods*; D009822:Oils, Volatile / Q000494:pharmacology*; D010938:Plant Oils; D031686:Tagetes / Q000737:chemistry; D013729:Terpenes
chemical_list: D000081005:Cyclohexane Monoterpenes; D053138:Cyclohexenes; D007306:Insecticides; D039821:Monoterpenes; D009822:Oils, Volatile; D010938:Plant Oils; D013729:Terpenes; C496656:piperitone; D000077222:Limonene; C044956:piperitenone