title: Comparison of the effect of Aminopielik D pesticide and its active components on human erythrocytes.
abstract: In the present work, the effect of Aminopielik D [417.5g/l of dimethylamino salts of 2,4-dichlorophenoxyacetic acid (2,4-D) and 32.5g/l of 3,6-dichloro-2-metoxybenzoic acid (Dicamba)] and its active components (used separately and in mixture) on human erythrocytes was examined. The parameters studied were: lipid peroxidation, metHb formation and catalase activity. Aminopielik D used at doses of 100-1000ppm was found to increase lipid peroxidation, decrease of catalase activity and oxidation of haemoglobin. 2,4-D and Dicamba are present in Aminopielik D in the dimethylamino form; their sodium salts in solution (separately and as a mixture) did not cause such strong effects. A synergistic action of 2,4-D and Dicamba was excluded as the individual compounds caused the same effects as their mixture. Aminopielik D provoked slightly higher changes in the lipid peroxidation and catalase activity than its active components alone and in mixture, which was probably a result of the properties of the additives and interaction of tested systems with the dimethylamino group.
authors.affiliation: Department of Biophysics of Environmental Pollution, University of Łódź, Banacha 12/16 Str., 90-237 Lódź, Poland.
authors.forename: Bożena
authors.initials: B
authors.lastname: Bukowska
authors.forename: Anna
authors.initials: A
authors.lastname: Kopka
authors.forename: Jaromir
authors.initials: J
authors.lastname: Michałowicz
authors.forename: Wirgiliusz
authors.initials: W
authors.lastname: Duda