title: West Nile virus infection in killer whale, Texas, USA, 2007.
abstract: In 2007, nonsuppurative encephalitis was identified in a killer whale at a Texas, USA, marine park. Panviral DNA microarray of brain tissue suggested West Nile virus (WNV); WNV was confirmed by reverse transcription PCR and sequencing. Immunohistochemistry demonstrated WNV antigen within neurons. WNV should be considered in cases of encephalitis in cetaceans.
authors.affiliation: SeaWorld, San Diego, California 92109, USA. judy.st.leger@seaworld.com
authors.forename: Judy
authors.initials: J
authors.lastname: St Leger
authors.forename: Guang
authors.initials: G
authors.lastname: Wu
authors.forename: Mark
authors.initials: M
authors.lastname: Anderson
authors.forename: Les
authors.initials: L
authors.lastname: Dalton
authors.forename: Erika
authors.initials: E
authors.lastname: Nilson
authors.forename: David
authors.initials: D
authors.lastname: Wang
mesh_terms: D000818:Animals; D000956:Antigens, Viral / Q000032:analysis; D001921:Brain / Q000821:virology; D018792:Encephalitis, Viral / Q000662:veterinary* / Q000821:virology; D017809:Fatal Outcome; D007150:Immunohistochemistry; D008297:Male; D020411:Oligonucleotide Array Sequence Analysis; D020133:Reverse Transcriptase Polymerase Chain Reaction; D017422:Sequence Analysis, DNA; D013781:Texas; D014901:West Nile Fever / Q000175:diagnosis / Q000662:veterinary* / Q000821:virology; D014902:West Nile virus / Q000145:classification / Q000235:genetics / Q000276:immunology / Q000302:isolation & purification*; D050685:Whale, Killer / Q000821:virology*
chemical_list: D000956:Antigens, Viral