title: Consolidation and reconsolidation: two lives of memories?
abstract: Most studies on memory consolidation consider the new information as if it were imposed on a tabula rasa, but considerable evidence indicates that new memories must be interleaved within a large network of relevant pre-existing knowledge. Early studies on reconsolidation highlighted that a newly consolidated memory could be erased after reactivation, but new evidence has shown that an effective reactivation experience must also involve memory reorganization to incorporate new learning. The combination of these observations on consolidation and reconsolidation highlights the fundamental similarities of both phenomena as the integration of new information and old, and it suggests reconsolidation = consolidation as a neverending process of schema modification.
authors.affiliation: Center for Memory and Brain, Boston University, Boston, MA 02215, USA.
authors.forename: Sam
authors.initials: S
authors.lastname: McKenzie
authors.forename: Howard
authors.initials: H
authors.lastname: Eichenbaum
mesh_terms: D000818:Animals; D001921:Brain / Q000033:anatomy & histology / Q000502:physiology*; D006801:Humans; D008568:Memory / Q000502:physiology*; D008954:Models, Biological; D009434:Neural Pathways / Q000502:physiology