title: [Biomarkers in rheumatoid arthritis].
abstract: The search for biomarkers in rheumatoid arthritis (RA) has been the object of interesting research in the past few years, although results have not always been relevant. Several biomarkers, from several different locations (blood, urine, synovial fluid, synovial tissue) and of different nature (autoantibodies, genetic markers, joint remodeling markers), and related to different outcomes, diagnostic and prognostic markers (joint destruction, disability, lack of remission, mortality, response to anti-rheumatic treatment, etc.) have been studied. The present article reviews research only on soluble biomarkers, mainly those in serum, related to the diagnosis and joint destruction in RA.
authors.affiliation: Unidad de Artritis, Servicio de Reumatología, Hospital Clínic de Barcelona, Barcelona, España. sanmarti@clinic.ub.es
authors.forename: Raimon
authors.initials: R
authors.lastname: Sanmartí
authors.forename: José A
authors.initials: JA
authors.lastname: Gómez-Puerta
mesh_terms: D000918:Antibody Specificity; D001172:Arthritis, Rheumatoid / Q000175:diagnosis / Q000188:drug therapy / Q000378:metabolism* / Q000473:pathology; D001323:Autoantibodies / Q000032:analysis / Q000276:immunology; D001324:Autoantigens / Q000276:immunology; D015415:Biomarkers / Q000032:analysis*; D001826:Body Fluids / Q000737:chemistry; D002956:Citrulline; D006801:Humans; D007596:Joints / Q000473:pathology; D010455:Peptides / Q000276:immunology; D011379:Prognosis; D012680:Sensitivity and Specificity; D016896:Treatment Outcome
chemical_list: D001323:Autoantibodies; D001324:Autoantigens; D015415:Biomarkers; D010455:Peptides; D002956:Citrulline