title: [Predictive value of immunological parameters on sepsis following abdominal operation for patients with HIV infection].
abstract: OBJECTIVE
  To study postoperative sepsis in HIV/AIDS patients who underwent abdominal operations.
  
  
  METHODS
  A retrospective analysis was performed to study 34 HIV/AIDS patients treated between January 2009 and December 2010 at the Shanghai Public Health Clinical Center Affiliated to Fudan University.
  
  
  RESULTS
  There were 31 males and 3 females in this cohort with a mean age of 45±13 years. Nineteen patients developed postoperative sepsis. The levels of preoperative CD4, postoperative CD4, preoperative CD4/CD8, and postoperative platelet were significantly lower than those without sepsis (all P<0.05). Among 19 patients with a preoperative CD4 cell count less than or equal to 200×10(6)/L, the incidence of postoperative sepsis rate was 84.2%(16/19), and for those with a preoperative CD4 cell count greater than 200×10(6)/L, the incidence of postoperative sepsis rate was 20.0%(3/15), the difference was statistically significant(P<0.05). There were 3 postoperative deaths.
  
  
  CONCLUSIONS
  CD4 cell count can be used as a predictive marker for the development of postoperative sepsis in patients with HIV/AIDS.
authors.affiliation: Department of Surgery, Shanghai Public Health Clinical Center Affiliated to Fudan University, Shanghai 201508, China.
authors.forename: Xian-jun
authors.initials: XJ
authors.lastname: Xia
authors.forename: Bao-chi
authors.initials: BC
authors.lastname: Liu
mesh_terms: D000005:Abdomen / Q000601:surgery; D000328:Adult; D000368:Aged; D018791:CD4 Lymphocyte Count; D015496:CD4-Positive T-Lymphocytes / Q000276:immunology; D005260:Female; D015658:HIV Infections / Q000150:complications / Q000276:immunology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D012189:Retrospective Studies; D018805:Sepsis / Q000209:etiology; D055815:Young Adult