title: Disinfection of dentinal tubules with two different formulations of calcium hydroxide as compared to 2% chlorhexidine: As intracanal medicaments against Enterococcus faecalis and Candida albicans: An in vitro study.
abstract: OBJECTIVE
  To evaluate the disinfection of dentinal tubules using calcium hydroxide with propylene glycol and calcium hydroxide with iodoform in silicone oil, as compared to 2% chlorhexidine gel.
  
  
  METHODS
  The antimicrobial efficacy of the medicaments against E.faecalis and C.albicans were assessed in vitro, using a dentinal tubule model at depths of 200 μm and 400 μm in extracted single rooted teeth. Saline was taken as the negative control (Group I) RESULTS: All three medicaments used in this study exerted antibacterial and antifungal activity. Group II (calcium hydroxide with propylene glycol) and Group IV (2% chlorhexidine gel) had the highest antimicrobial activity and the differences between their antibacterial activities were not statistically significant. Group III (calcium hydroxide with iodoform in silicone oil) and Group IV had the highest antifungal activity and the differences between their antifungal activities were not statistically significant. The inhibition of growth at 200 μm and 400 μm was uniform, with no statistical difference.
  
  
  CONCLUSIONS
  Two percent chlorhexidine gel was effective against both E.faecalis and C.albicans. Calcium hydroxide with propylene glycol was the most effective intracanal medicament along with 2% chlorhexidine against E.faecalis, whereas, calcium hydroxide with iodoform in silicone oil was the most effective intracanal medicament along with 2% chlorhexidine against C.albicans.
authors.affiliation: Department of Conservative Dentistry and Endodontics, Kothiwal Dental College Research Center and Hospital, Moradabad, India.
authors.forename: Dakshita Joy
authors.initials: DJ
authors.lastname: Vaghela
authors.forename: Deivanayagam
authors.initials: D
authors.lastname: Kandaswamy
authors.forename: Nagendrababu
authors.initials: N
authors.lastname: Venkateshbabu
authors.forename: Narasimman
authors.initials: N
authors.lastname: Jamini
authors.forename: Arathi
authors.initials: A
authors.lastname: Ganesh