title: [Next-generation sequencing technologies and the application in microbiology--a review].
abstract: Since its invention in 1970s, nucleic acid sequencing technology has contributed tremendously to the genomics advances. The next-generation sequencing technologies, represented by HiSeq 2000 from Illumina, SOLiD from Applied Biosystems and 454 from Roche, re-energized the application of genomics. In this review, we first introduced the next-generation sequencing technologies, then, described their potential applications in the field of microbiology.
authors.affiliation: BGI-Shenzhen, Shenzhen 518083, China. qinnan@gmail.com
authors.forename: Nan
authors.initials: N
authors.lastname: Qin
authors.forename: Dongfang
authors.initials: D
authors.lastname: Li
authors.forename: Ruifu
authors.initials: R
authors.lastname: Yang
mesh_terms: D001419:Bacteria / Q000235:genetics*; D023281:Genomics / Q000295:instrumentation / Q000379:methods*; D008828:Microbiological Techniques / Q000295:instrumentation / Q000379:methods*; D008829:Microbiology; D017422:Sequence Analysis, DNA / Q000295:instrumentation / Q000379:methods* / Q000639:trends