title: [Study of human papillomavirus in small cell neuroendocrine carcinoma of the uterine cervix].
abstract: OBJECTIVE
  To observe the infection of the high risk human papillomavirus (HPV) in the specimen of the small cell neuroendocrine carcinoma of the uterine cervix (SCNEC).
  
  
  METHODS
  We extracted the nucleic acids in the formalin-fixed and paraffin-embedded specimen from a 33-year-old patient diagnosed as small cell neuroendocrine carcinoma of uterine cervix and detected the HPV genotype with the nested PCR.
  
  
  RESULTS
  We identified HPV18, a high-risk genotype, in the specimen.
  
  
  CONCLUSIONS
  The HPV detection with the nested PCR was available for identification of the HPV genotype(s) in the paraffin-embedded specimens of small cell neuroendocrine carcinoma of the uterine cervix with a high accuracy and sensitivity.
authors.affiliation: Department of Obstetrics and Gynaecology, Chinese PLA General Hospital, Beijing 100853, China.
authors.forename: Li-hua
authors.initials: LH
authors.lastname: Bian
authors.forename: Xiao-li
authors.initials: XL
authors.lastname: Wang
authors.forename: Yi-fan
authors.initials: YF
authors.lastname: Guo
authors.forename: Xiao-zhou
authors.initials: XZ
authors.lastname: Wu
authors.forename: Lei
authors.initials: L
authors.lastname: Song
authors.forename: Hong-tu
authors.initials: HT
authors.lastname: Liu
mesh_terms: D000328:Adult; D001483:Base Sequence; D018278:Carcinoma, Neuroendocrine / Q000821:virology*; D018288:Carcinoma, Small Cell / Q000821:virology*; D005260:Female; D052161:Human papillomavirus 18 / Q000235:genetics / Q000302:isolation & purification*; D006801:Humans; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D002583:Uterine Cervical Neoplasms / Q000821:virology*