title: Coccidioidomycosis during pregnancy: a review and recommendations for management.
abstract: Pregnancy is an established risk factor for the development of severe and disseminated coccidioidomycosis, particularly when infection is acquired during the later stages of gestation. Although recent studies suggest that the incidence of symptomatic coccidioidomycosis during pregnancy is decreasing and that outcome has improved, management is complicated by the observations that azole antifungal agents can be teratogenic when given to some women, particularly at high doses, early in pregnancy. This article summarizes the data on these issues and offers guidance on the management of coccidioidomycosis during pregnancy.
authors.affiliation: University of California, San Diego, California, USA.
authors.forename: Robert S
authors.initials: RS
authors.lastname: Bercovitch
authors.forename: Antonino
authors.initials: A
authors.lastname: Catanzaro
authors.forename: Brian S
authors.initials: BS
authors.lastname: Schwartz
authors.forename: Demosthenes
authors.initials: D
authors.lastname: Pappagianis
authors.forename: D Heather
authors.initials: DH
authors.lastname: Watts
authors.forename: Neil M
authors.initials: NM
authors.lastname: Ampel
mesh_terms: D000818:Animals; D000935:Antifungal Agents / Q000009:adverse effects / Q000627:therapeutic use; D003047:Coccidioidomycosis / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000188:drug therapy* / Q000382:microbiology*
chemical_list: D000935:Antifungal Agents