title: Comparative clinical dosimetry with X-knife and gamma knife.
abstract: X-knife and gamma knife techniques are well-established for cranial stereotactic radiosurgery (SRS). Due to differences in their radiation delivery methods, some of the dosimetric parameters of these two techniques differ which may have clinical significance. There are many dosimetric studies comparing linear accelerator based techniques such as X-knife with gamma knife but generally from different institutions. We carried out a retrospective comparative study of the dosimetric parameters of the SRS treatments performed at our centre with X-knife (circular cones) and gamma knife. Our results indicate that the dose conformity and dose fall-off in the vicinity of the target volumes were better for patients treated with gamma knife as compared to X-knife. However, the dose fall-off pattern shows a reversal at a larger distance from the target. It was better for the X-knife as compared to gamma knife in the low dose region.
authors.affiliation: Department of Radiotherapy, Army Hospital Research & Referral, New Delhi 110010, India. manojsemwal@yahoo.co.in
authors.forename: M K
authors.initials: MK
authors.lastname: Semwal
authors.forename: Sukhvir
authors.initials: S
authors.lastname: Singh
authors.forename: A
authors.initials: A
authors.lastname: Sarin
authors.forename: S
authors.initials: S
authors.lastname: Bhatnagar
authors.forename: H C
authors.initials: HC
authors.lastname: Pathak
mesh_terms: D006801:Humans; D009369:Neoplasms / Q000532:radiotherapy / Q000601:surgery; D011874:Radiometry; D016634:Radiosurgery / Q000379:methods*; D014964:X-Ray Therapy / Q000379:methods*