title: 1,1'-(3-methyl-4-phenylthieno[2,3-b]thiophene-2,5-diyl)diethanone as a building block in heterocyclic synthesis. Novel synthesis of some pyrazole and pyrimidine derivatives.
abstract: A series of new bis(heterocycles) featuring thieno[2,3-b]thiophene rings was synthesized in a combinatorial manner. Intramolecular cyclization of enaminone derivatives with appropriate N-nucleophiles afforded the target compounds. All compounds were characterized by ¹H-, ¹³C-NMR, GCMS, IR, and UV-Vis spectrometry. These compounds represent a new class of sulfur- and nitrogen-containing heterocycles that should also be of interest as new materials.
authors.affiliation: Department of Chemistry, Faculty of Science, King Saud University, P. O. Box 2455, Riyadh 11451, Saudi Arabia. Yahia@ksu.edu.sa
authors.forename: Yahia Nasser
authors.initials: YN
authors.lastname: Mabkhot
authors.forename: Abdullah Mohammed
authors.initials: AM
authors.lastname: Al-Majid
authors.forename: Assem
authors.initials: A
authors.lastname: Barakat
authors.forename: Saeed
authors.initials: S
authors.lastname: Alshahrani
authors.forename: Yamin
authors.initials: Y
authors.lastname: Siddiqui
mesh_terms: D001688:Biological Products / Q000138:chemical synthesis*; D002626:Chemistry, Pharmaceutical / Q000379:methods*; D020650:Combinatorial Chemistry Techniques; D003500:Cyclization; D009682:Magnetic Resonance Spectroscopy; D009584:Nitrogen / Q000737:chemistry; D011720:Pyrazoles / Q000138:chemical synthesis*; D011743:Pyrimidines / Q000138:chemical synthesis*; D013455:Sulfur / Q000737:chemistry; D013876:Thiophenes / Q000737:chemistry
chemical_list: D001688:Biological Products; D011720:Pyrazoles; D011743:Pyrimidines; D013876:Thiophenes; D013455:Sulfur; D009584:Nitrogen