title: A domino Michael/Dieckmann process as an entry to α-(hydroxymethyl)glutamic acid.
abstract: A domino process that involves a Michael-type addition followed by a Dieckmann reaction mediated by the participation of the cyclic carbamate group is the key step in the synthesis of both enantiomers of α-(hydroxymethyl)glutamic acid (HMG).
authors.affiliation: Departamento de Química, Universidad de La Rioja, Centro de Investigación en Síntesis Química, UA-CSIC, 26006 Logroño, Spain.
authors.forename: Carlos
authors.initials: C
authors.lastname: Aydillo
authors.forename: Gonzalo
authors.initials: G
authors.lastname: Jiménez-Osés
authors.forename: Alberto
authors.initials: A
authors.lastname: Avenoza
authors.forename: Jesús H
authors.initials: JH
authors.lastname: Busto
authors.forename: Jesús M
authors.initials: JM
authors.lastname: Peregrina
authors.forename: María M
authors.initials: MM
authors.lastname: Zurbano
mesh_terms: D002219:Carbamates / Q000737:chemistry; D003500:Cyclization; D005971:Glutamates / Q000737:chemistry*; D008958:Models, Molecular; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: C449086:(hydroxymethyl)glutamic acid; D002219:Carbamates; D005971:Glutamates