title: Patients' report of statins use and side-effects in a sample of hospitalized cardiac patients in the Islamic Republic of Iran.
abstract: We aim to study the prevalence of the side-effects of statins among Iranians patients admitted to a cardiac-specialized hospital and had taken statins prior to hospitalization. Data was collected between September 2007 and March 2008 and 200 patients were enrolled. A questionnaire was completed using the patients' records and by interviewing the patients. The mean age of the participants was 61.5 (SD 12.3) years and 63% were males. The most commonly used statins was atrovastatin (99% of the patients). In all, 63.5% of the participants reported experiencing side-effects due to statins. The reported side-effects were respiratory (18.5%), headache (16.5%), rash (0.5%) and allergic reactions (5%); 9.5% reported (4%) and gastrointestinal effect muscle-related side-effects such as myalgia. Although, the clinical benefits outweigh the small risk of liver failure and myopathy, clinicians should be aware of the side-effects of statins.
authors.affiliation: National Public Health Management Centre, Clinical Pharmacy Department, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Islamic Republic of Iran. mashayekhis@yahoo.co.uk
authors.forename: S O
authors.initials: SO
authors.lastname: Mashayekhi
authors.forename: M
authors.initials: M
authors.lastname: Ghandforoush-Sattari
authors.forename: M E
authors.initials: ME
authors.lastname: Baghdadchi
authors.forename: M
authors.initials: M
authors.lastname: Kheyri
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003430:Cross-Sectional Studies; D005260:Female; D006331:Heart Diseases; D006760:Hospitalization; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000009:adverse effects* / Q000627:therapeutic use; D007492:Iran; D008297:Male; D008875:Middle Aged; D011795:Surveys and Questionnaires
chemical_list: D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors