title: Red blood cell products: consideration of the discrepant temperature ranges permitted for storage versus transport.
abstract: The focus of this study was to determine if there is significant data to prohibit short-term storage of red blood cells (RBCs; i.e., <24 hr) at 1 to 10°C rather than 1 to 6°C, which occurs not uncommonly when RBCs are stored in a cooler for a patient during surgery. This document will describe the evidence in the literature to date regarding the potential impact of having RBCs temporarily in the 1 to 10°C range versus in the 1 to 6°C range, if any, on key measures of the quality of RBC storage: potassium, adenosine triphosphate, 2,3-diphosphoglycerate, posttransfusion survival, and bacterial contamination.
authors.affiliation: Transfusion Medicine, Department of Pathology, University of Illinois at Chicago, Chicago, Illinois 60612, USA. scampbe@uic.edu
authors.forename: Sally
authors.initials: S
authors.lastname: Campbell Lee
authors.forename: Beth
authors.initials: B
authors.lastname: Shaz
authors.forename: Roberto
authors.initials: R
authors.lastname: Arena
authors.forename: Steven
authors.initials: S
authors.lastname: Sloan
authors.forename: Mark
authors.initials: M
authors.lastname: Fung
authors.forename: Glenn
authors.initials: G
authors.lastname: Ramsey
mesh_terms: D019794:2,3-Diphosphoglycerate / Q000737:chemistry; D000255:Adenosine Triphosphate / Q000737:chemistry; D001793:Blood Preservation / Q000379:methods*; D004912:Erythrocytes / Q000737:chemistry*; D006801:Humans; D011188:Potassium / Q000737:chemistry; D013696:Temperature
chemical_list: D019794:2,3-Diphosphoglycerate; D000255:Adenosine Triphosphate; D011188:Potassium