title: Combined toxicity of the mixtures of phenol and aniline derivatives to Vibrio qinghaiensis sp.-Q67.
abstract: To test whether the dose addition and independent action models can predict the combined toxicity of the mixtures of phenol and aniline derivatives, six phenolic and two aniline derivatives were selected as the test components. The inhibition toxicity of the derivatives and their mixtures to Vibrio qinghaiensis sp.-Q67 indicated that all dose-response relationships could be effectively described by the Weibull function with correlation coefficients greater than 0.99. The combined toxicity of two equivalent-effect concentration ratio mixtures and eight uniform design concentration ratio mixtures could be predicted successfully by the dose addition model within 95% confidence intervals. However, it was also well predicted by the independent action model, especially at lower concentrations.
authors.affiliation: College of Environmental Science and Engineering, Guilin University of Technology, 541004 Guilin, People's Republic of China.
authors.forename: Ling-Yun
authors.initials: LY
authors.lastname: Mo
authors.forename: Shu-Shen
authors.initials: SS
authors.lastname: Liu
authors.forename: Yi-Nian
authors.initials: YN
authors.lastname: Zhu
authors.forename: Hai-Ling
authors.initials: HL
authors.lastname: Liu
authors.forename: Hong-Yan
authors.initials: HY
authors.lastname: Liu
authors.forename: Zhong-Sheng
authors.initials: ZS
authors.lastname: Yi
mesh_terms: D000814:Aniline Compounds / Q000633:toxicity*; D004305:Dose-Response Relationship, Drug; D010636:Phenols / Q000633:toxicity*; D014733:Vibrio / Q000187:drug effects*; D014874:Water Pollutants, Chemical / Q000633:toxicity*
chemical_list: D000814:Aniline Compounds; D010636:Phenols; D014874:Water Pollutants, Chemical; C023650:aniline