title: Outcome of cochlear implantation in asymptomatic congenital cytomegalovirus deafened children.
abstract: OBJECTIVE
  Congenital cytomegalovirus (cCMV) infection is a common cause of sensorineural hearing loss (SNHL). The incidence of SNHL is higher in symptomatic cCMV infants and is usually identified early. By contrast, the incidence of SNHL is lower in children with asymptomatic cCMV, and the hearing loss can be delayed in onset and progressive. The objective was to compare the outcome of cochlear implantation in children deafened by cCMV with a control group of children with implants who do not have the condition.
  
  
  METHODS
  Retrospective review of case notes and data base.
  
  
  METHODS
  Retrospective review of 14 children with asymptomatic cCMV who underwent cochlear implantation. Their outcome measures were compared with those of a matched population by using standard assessment tools.
  
  
  RESULTS
  In the study group, the Modified Categories of Auditory Performance (M-CAP) score (range, 1-7) ranged from 2 to 7 (mean, 4.2). In the control group, the M-CAP ranged from 5 to 7 (mean, 6.0). In the study group, the Manchester Spoken Language Development Scale (MSLDS) score (range, 1-10) ranged from 1 to 9 (mean, 5.4). In the control group, the MSLDS ranged from 3 to 10 (mean, 8.1).
  
  
  CONCLUSIONS
  Children with asymptomatic deafness caused by cCMV benefit from cochlear implantation but perform less well than a comparable group of children with implants who do not have cCMV. There is a range of performance in the cCMV group that may relate to the degree of motor or cognitive disabilities.
authors.affiliation: Department of Otorhinolaryngology-Head and Neck Surgery, Manchester Royal Infirmary, Central Manchester University Hospitals NHS Foundation Trust, Manchester, United Kingdom. malikvik@yahoo.com
authors.forename: Vikas
authors.initials: V
authors.lastname: Malik
authors.forename: Iain A
authors.initials: IA
authors.lastname: Bruce
authors.forename: Stephen J
authors.initials: SJ
authors.lastname: Broomfield
authors.forename: Lisa
authors.initials: L
authors.lastname: Henderson
authors.forename: Kevin M J
authors.initials: KM
authors.lastname: Green
authors.forename: Richard T
authors.initials: RT
authors.lastname: Ramsden
mesh_terms: D058070:Asymptomatic Diseases; D002648:Child; D002675:Child, Preschool; D019929:Cochlear Implantation; D003586:Cytomegalovirus Infections / Q000150:complications* / Q000151:congenital* / Q000175:diagnosis; D005260:Female; D006319:Hearing Loss, Sensorineural / Q000150:complications / Q000503:physiopathology / Q000601:surgery* / Q000821:virology; D006320:Hearing Tests; D006801:Humans; D007859:Learning Disabilities / Q000209:etiology; D008297:Male; D016896:Treatment Outcome