title: Adrenocortical carcinoma masquerading as a benign adenoma on computed tomography washout study.
abstract: An incidental adrenal mass is a common finding on cross-sectional imaging, with most of these lesions being benign adenomas. Indications for adrenalectomy turn on the likelihood that a mass is malignant or whether it exhibits metabolic activity. Modern imaging is considered highly accurate in differentiating adrenal adenomas from other adrenal pathology. We present a case of a 5-cm adrenal lesion with computed tomography washout characteristics consistent with a benign adenoma, which proved upon resection to be an adrenocortical carcinoma.
authors.affiliation: Department of Pathology, Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111, USA.
authors.forename: Jay
authors.initials: J
authors.lastname: Simhan
authors.forename: Daniel
authors.initials: D
authors.lastname: Canter
authors.forename: Ervin
authors.initials: E
authors.lastname: Teper
authors.forename: Marc C
authors.initials: MC
authors.lastname: Smaldone
authors.forename: Ninad
authors.initials: N
authors.lastname: Patil
authors.forename: Arthur
authors.initials: A
authors.lastname: Patchefsky
authors.forename: Marlane C
authors.initials: MC
authors.lastname: Guttmann
authors.forename: Barton
authors.initials: B
authors.lastname: Milestone
authors.forename: Yu-Ning
authors.initials: YN
authors.lastname: Wong
authors.forename: Lisa A
authors.initials: LA
authors.lastname: Hicks
authors.forename: Robert G
authors.initials: RG
authors.lastname: Uzzo
authors.forename: Alexander
authors.initials: A
authors.lastname: Kutikov
mesh_terms: D000236:Adenoma / Q000175:diagnosis*; D000306:Adrenal Cortex Neoplasms / Q000000981:diagnostic imaging* / Q000601:surgery; D000315:Adrenalectomy; D002277:Carcinoma / Q000000981:diagnostic imaging* / Q000601:surgery; D003287:Contrast Media / Q000493:pharmacokinetics; D003937:Diagnosis, Differential; D003951:Diagnostic Errors; D005260:Female; D006801:Humans; D033162:Incidental Findings; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D014057:Tomography, X-Ray Computed
chemical_list: D003287:Contrast Media