title: Thrombosis in children with acute lymphoblastic leukemia treated at a tertiary care center in Lebanon: revisiting the role of predictive models.
abstract: The incidence of symptomatic venous thromboembolism (VTE) in children receiving therapy for acute lymphoblastic leukemia (ALL) varies widely and is protocol dependent. The authors herein report the incidence and potential risk factors for VTE in children with ALL while being treated on a uniform protocol at a single tertiary care center in Lebanon. The authors also examine necessary modifications in a recently published model before it could predict VTE in their patients.
authors.affiliation: Department of Pediatrics, Children's Cancer Center of Lebanon, American University of Beirut Medical Center, Beirut, Lebanon.
authors.forename: Carol
authors.initials: C
authors.lastname: Al-Aridi
authors.forename: Miguel R
authors.initials: MR
authors.lastname: Abboud
authors.forename: Raya
authors.initials: R
authors.lastname: Saab
authors.forename: Dalia
authors.initials: D
authors.lastname: Eid
authors.forename: Sima
authors.initials: S
authors.lastname: Jeha
authors.forename: Anthony K C
authors.initials: AK
authors.lastname: Chan
authors.forename: Samar A
authors.initials: SA
authors.lastname: Muwakkit
mesh_terms: D000293:Adolescent; D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects* / Q000627:therapeutic use; D001215:Asparaginase / Q000009:adverse effects* / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D004926:Escherichia coli / Q000201:enzymology; D005260:Female; D006801:Humans; D007223:Infant; D007861:Lebanon; D008297:Male; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000175:diagnosis / Q000188:drug therapy*; D011237:Predictive Value of Tests; D012189:Retrospective Studies; D012307:Risk Factors; D012680:Sensitivity and Specificity; D016896:Treatment Outcome; D054556:Venous Thromboembolism / Q000175:diagnosis / Q000188:drug therapy*; D055815:Young Adult
chemical_list: D001215:Asparaginase