title: Prevention of infections associated with combat-related burn injuries.
abstract: Burns are a very real component of combat-related injuries, and infections are the leading cause of mortality in burn casualties. The prevention of infection in the burn casualty transitioning from the battlefield to definitive care provided at the burn center is critical in reducing overall morbidity and mortality. This review highlights evidence-based medicine recommendations using military and civilian data to provide the most comprehensive, up-to-date management strategies for initial care of burned combat casualties. Areas of emphasis include antimicrobial prophylaxis, debridement of devitalized tissue, topical antimicrobial therapy, and optimal time to wound coverage. This evidence-based medicine review was produced to support the Guidelines for the Prevention of Infections Associated With Combat-Related Injuries: 2011 Update contained in this supplement of Journal of Trauma.
authors.affiliation: US Air Force Medical Support Agency, Lackland Air Force Base, TX 78235, USA. laurie.davignon@us.af.mil
authors.forename: Laurie C
authors.initials: LC
authors.lastname: D'Avignon
authors.forename: Kevin K
authors.initials: KK
authors.lastname: Chung
authors.forename: Jeffery R
authors.initials: JR
authors.lastname: Saffle
authors.forename: Evan M
authors.initials: EM
authors.lastname: Renz
authors.forename: Leopoldo C
authors.initials: LC
authors.lastname: Cancio
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002056:Burns / Q000150:complications* / Q000382:microbiology / Q000628:therapy; D003646:Debridement; D006801:Humans; D008887:Military Medicine; D017410:Practice Guidelines as Topic; D014857:Warfare; D014946:Wound Infection / Q000209:etiology / Q000517:prevention & control*
chemical_list: D000900:Anti-Bacterial Agents