title: Two out of three required: a case of incomplete Carney triad.
abstract: A 48-year-old woman presented with chest symptoms. Multiple lesions seen on chest imaging were found to be pulmonary chondromas following surgical resection. Whole body magnetic resonance scan performed to investigate the possibility of Carney triad demonstrated a gastric lesion. This was resected and found to be a gastrointestinal stromal tumor. No evidence of paragangliomata was found on imaging. A diagnosis of incomplete Carney triad was made. Carney triad is a rare multiple neoplastic association of pulmonary chondroma, gastrointestinal stromal tumor, and paraganglioma. At least 2 tumors are required for diagnosis. Most patients are young women. No genetic cause has been identified. Management involves surgical resection of tumors and follow-up for recurrence and investigation for other elements of the triad.
authors.affiliation: Department of Hepatopancreatobiliary and General Surgery, North Manchester General Hospital, Manchester, UK. finbar.slevin@pat.nhs.uk
authors.forename: Finbar
authors.initials: F
authors.lastname: Slevin
authors.forename: Patricia
authors.initials: P
authors.lastname: Duncan
authors.forename: Patrick
authors.initials: P
authors.lastname: Shenjere
authors.forename: Michael
authors.initials: M
authors.lastname: Leahy
authors.forename: Gareth
authors.initials: G
authors.lastname: Evans
authors.forename: David
authors.initials: D
authors.lastname: Sherlock
mesh_terms: D056733:Carney Complex / Q000473:pathology*; D002812:Chondroma / Q000150:complications / Q000473:pathology*; D005260:Female; D005770:Gastrointestinal Neoplasms / Q000150:complications / Q000473:pathology*; D046152:Gastrointestinal Stromal Tumors / Q000150:complications / Q000473:pathology*; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications / Q000473:pathology*; D008875:Middle Aged