title: Bilateral tonsillar and esophageal Kaposi sarcoma in an HIV-negative patient.
abstract: Tonsillar involvement in Kaposi sarcoma is extremely rare, as only a few such cases have been reported; all but 1 of these previously reported cases occurred in patients with human immunodeficiency virus (HIV) infection. We describe what to the best of our knowledge is the first reported case of concurrent bilateral tonsillar and esophageal Kaposi sarcoma in an HIV-negative patient. A 68-year-old man presented with sore throat and dysphagia. Clinical examination revealed the presence of bilateral and asymmetrical tonsillar masses, as well as generalized lymphadenopathy in the cervical chain. The masses were resected, and findings on histopathologic analysis were consistent with Kaposi sarcoma. In addition, human herpesvirus 8 was demonstrated on a tonsil specimen by polymerase chain reaction, and microinvasive squamous cell carcinoma was also detected. Later, another Kaposi sarcoma lesion was detected in the lower third of the esophagus. We recommend that clinicians not discount the possibility of oral classic Kaposi sarcoma in the workup of an immunocompetent patient with oral vascular lesions.
authors.affiliation: Department of Pathology, Akdeniz University School of Medicine, Tip Fakultesi Patoloji AD, Antalya, Turkey. iremhicrang@hotmail.com
authors.forename: Irem Hicran
authors.initials: IH
authors.lastname: Ozbudak
authors.forename: Kenan
authors.initials: K
authors.lastname: Guney
authors.forename: Derya
authors.initials: D
authors.lastname: Mutlu
authors.forename: Tekinalp
authors.initials: T
authors.lastname: Gelen
authors.forename: Gulay
authors.initials: G
authors.lastname: Ozbilim
mesh_terms: D000368:Aged; D003951:Diagnostic Errors; D004938:Esophageal Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D018023:HIV Seronegativity; D006801:Humans; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis*; D012514:Sarcoma, Kaposi / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D014067:Tonsillar Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy