title: Synthesis of mono, bis-2-(2-arylideneaminophenyl) indole azomethines as potential antimicrobial agents.
abstract: A series of mono and bis 2-2-(arylidineaminophenyl)indole azomethines have been synthesized by a condensation reaction of 2-(2-amino phenyl) indole with various mono and diketones R-CO-R(l) /R-CO-X-CO-R(l) (1:1/2:1 ratio) in ethanol media. The synthesized azomethines were characterized via IR, (1)H-NMR, (13)C-NMR, MS and elemental analysis. The antimicrobial activity of these compounds against different bacteria and fungi was also evaluated.
authors.affiliation: Department of Chemistry, Kakatiya University, Warangal 506009, A.P, India.
authors.forename: Rondla
authors.initials: R
authors.lastname: Rohini
authors.forename: P Muralidhar
authors.initials: PM
authors.lastname: Reddy
authors.forename: Kanne
authors.initials: K
authors.lastname: Shanker
authors.forename: Kodipelli
authors.initials: K
authors.lastname: Kanthaiah
authors.forename: Vadde
authors.initials: V
authors.lastname: Ravinder
authors.forename: Anren
authors.initials: A
authors.lastname: Hu
mesh_terms: D000890:Anti-Infective Agents / Q000032:analysis / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D001391:Azo Compounds / Q000032:analysis / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects; D005658:Fungi / Q000187:drug effects; D007211:Indoles / Q000032:analysis / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D013329:Structure-Activity Relationship; D013882:Thiosemicarbazones / Q000032:analysis / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*
chemical_list: D000890:Anti-Infective Agents; D001391:Azo Compounds; D007211:Indoles; D013882:Thiosemicarbazones; C512188:azomethine