title: Molecular markers that can be utilized in diet and dietary supplement research.
abstract: Prostate and other cancers have a multitude of potential markers that can be used in laboratory and clinical studies of diet and dietary supplement interventions. More overt clinical markers include imaging tests, biopsy samples, prostate-specific antigen kinetics, and urinary testing. Many molecular markers are currently available, including antiapoptotic and apoptotic proteins, cell adhesion molecules, cell cycle compounds, growth factors, angiogenic markers, and proliferative and inflammatory signals. Protein kinases and transcription factors should also be considered for diversity. Testing of numerous molecular markers has become critical in gaining preliminary insight into the potential impact of a novel diet and supplemental agents.
authors.affiliation: Department of Urology, University of Michigan Medical Center, 1500 East Medical Center Drive, Ann Arbor, MI 48109-0330, USA. moyad@umich.edu
authors.forename: Mark A
authors.initials: MA
authors.lastname: Moyad
authors.forename: Kirk J
authors.initials: KJ
authors.lastname: Wojno
mesh_terms: D015415:Biomarkers / Q000032:analysis; D035843:Biomedical Research / Q000379:methods*; D004032:Diet; D019587:Dietary Supplements; D006801:Humans; D011506:Proteins / Q000032:analysis
chemical_list: D015415:Biomarkers; D011506:Proteins