title: High chemoselectivity in the phenol synthesis.
abstract: Efforts to trap early intermediates of the gold-catalyzed phenol synthesis failed. Neither inter- nor intramolecularly offered vinyl groups, ketones or alcohols were able to intercept the gold carbenoid species. This indicates that the competing steps of the gold-catalyzed phenol synthesis are much faster than the steps of the interception reaction. In the latter the barrier of activation is higher. At the same time this explains the high tolerance of this very efficient and general reaction towards functional groups.
authors.affiliation: Organisch-Chemisches Institut, Ruprecht-Karls-Universität Heidelberg, Im Neuenheimer Feld 270, 69120 Heidelberg, Germany.
authors.forename: Matthias
authors.initials: M
authors.lastname: Rudolph
authors.forename: Melissa Q
authors.initials: MQ
authors.lastname: McCreery
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Frey
authors.forename: A Stephen K
authors.initials: AS
authors.lastname: Hashmi