title: Modular synthesis of naphthothiophenes by Pd-catalyzed tandem direct arylation/Suzuki coupling.
abstract: A short and highly modular three-step synthesis of a new class of substituted naphthothiophenes has been developed exploiting a Pd-catalyzed tandem direct arylation/Suzuki coupling transformation as the key step.
authors.affiliation: Davenport Laboratories, Department of Chemistry, University of Toronto, Toronto, Ontario, Canada M5S 3H6.
authors.forename: Norman
authors.initials: N
authors.lastname: Nicolaus
authors.forename: Patrick T
authors.initials: PT
authors.lastname: Franke
authors.forename: Mark
authors.initials: M
authors.lastname: Lautens
mesh_terms: D002384:Catalysis; D008958:Models, Molecular; D015394:Molecular Structure; D009284:Naphthols / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*; D013876:Thiophenes / Q000138:chemical synthesis*
chemical_list: D009284:Naphthols; D013876:Thiophenes; D010165:Palladium