title: [Difficult decisions in stroke therapy].
abstract: In numerous situations stroke physicians face a lack of evidence during their daily practice. In this report the authors address some of the difficult treatment decisions encountered in acute therapy and secondary prevention. Examples include off-label thrombolysis and prevention in high-risk situations. The available data from trials and registries are discussed, and personal views and recommendations are expressed.
authors.affiliation: Klinik und Hochschulambulanz für Neurologie, Charité - Universitätsmedizin Berlin, Campus Charité Mitte, Berlin, Deutschland.
authors.forename: M
authors.initials: M
authors.lastname: Endres
authors.forename: M
authors.initials: M
authors.lastname: Grond
authors.forename: W
authors.initials: W
authors.lastname: Hacke
authors.forename: M
authors.initials: M
authors.lastname: Ebinger
authors.forename: P D
authors.initials: PD
authors.lastname: Schellinger
authors.forename: M
authors.initials: M
authors.lastname: Dichgans
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000959:Antihypertensive Agents / Q000009:adverse effects / Q000627:therapeutic use; D001281:Atrial Fibrillation / Q000150:complications / Q000188:drug therapy / Q000401:mortality; D001786:Blood Glucose / Q000378:metabolism; D002543:Cerebral Hemorrhage / Q000188:drug therapy / Q000401:mortality; D002986:Clinical Trials as Topic; D003937:Diagnosis, Differential; D016894:Endarterectomy, Carotid; D004827:Epilepsy / Q000175:diagnosis; D019317:Evidence-Based Medicine; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000188:drug therapy / Q000401:mortality; D019934:International Normalized Ratio; D056687:Off-Label Use; D010644:Phenprocoumon / Q000009:adverse effects / Q000627:therapeutic use; D010975:Platelet Aggregation Inhibitors / Q000009:adverse effects / Q000627:therapeutic use; D012042:Registries; D012307:Risk Factors; D055502:Secondary Prevention; D020521:Stroke / Q000401:mortality / Q000517:prevention & control / Q000628:therapy*; D016019:Survival Analysis; D015912:Thrombolytic Therapy / Q000009:adverse effects / Q000379:methods; D016896:Treatment Outcome
chemical_list: D000959:Antihypertensive Agents; D001786:Blood Glucose; D010975:Platelet Aggregation Inhibitors; D010644:Phenprocoumon