title: Behcet's disease and IgA nephropathy.
abstract: Although Behçet's disease (BD) is a kind of systemic disease, renal involvement is rare, especially IgA nephropathy (IgAN). Renal manifestations in BD range from mild urinary abnormalities to glomerulonephritis with persistent renal failure, which includes minimal change disease, proliferative glomerulonephritis, rapidly crescentic glomerulonephritis, renal amyloidosis and IgA nephropathy. Amyloidosis seems to be the most common type of renal lesion in BD, and several cases of nephrotic syndrome secondary to amyloidosis have been documented. Co-occurrence of BD and IgA nephropathy has only been reported in only few cases. We describe two patients with the rare association of BD and IgAN. We suggested that it is important to periodically perform renal function assessment in patients with BD, through urinalysis and measurement of serum creatinine for detecting any abnormality and providing an early adequate treatment.
authors.forename: Mustafa
authors.initials: M
authors.lastname: Altay
authors.forename: Sema
authors.initials: S
authors.lastname: Secilmis
authors.forename: Selman
authors.initials: S
authors.lastname: Unverdi
authors.forename: Mevlut
authors.initials: M
authors.lastname: Ceri
authors.forename: Murat
authors.initials: M
authors.lastname: Duranay
mesh_terms: D001241:Aspirin / Q000627:therapeutic use; D001528:Behcet Syndrome / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D003078:Colchicine / Q000627:therapeutic use; D003404:Creatinine / Q000097:blood / Q000652:urine; D004359:Drug Therapy, Combination; D005922:Glomerulonephritis, IGA / Q000150:complications / Q000175:diagnosis*; D006801:Humans; D007677:Kidney Function Tests; D008297:Male; D008875:Middle Aged; D009543:Nifedipine / Q000627:therapeutic use; D016896:Treatment Outcome; D014665:Vasodilator Agents / Q000627:therapeutic use; D055815:Young Adult
chemical_list: D014665:Vasodilator Agents; D003404:Creatinine; D009543:Nifedipine; D001241:Aspirin; D003078:Colchicine