title: Expeditious entry to novel 2-methylene-2,3-dihydrofuro[3,2-c] chromen-2-ones from 6-chloro-4-hydroxychromen-2-one and propargylic alcohols.
abstract: A catalytic system consisting of the ruthenium(II) complex [Ru(η³-2-C3H4Me)(CO)(dppf)][SbF6] (dppf=1,1'-bis(diphenylphosphino)ferrocene) and trifluoroacetic acid has been used to promote the coupling of secondary propargylic alcohols with 6-chloro-4-hydroxychromen-2-one. The reactions afforded unusual 2-methylene-2,3-dihydrofuro[3,2-c]chromen-2-ones in good yields.
authors.affiliation: Departamento de Química Orgánica e Inorgánica, IUQOEM-CSIC, Facultad de Química, Universidad de Oviedo, E-33071 Oviedo, Spain.
authors.forename: Noel
authors.initials: N
authors.lastname: Nebra
authors.forename: Alba E
authors.initials: AE
authors.lastname: Díaz-Álvarez
authors.forename: Josefina
authors.initials: J
authors.lastname: Díez
authors.forename: Victorio
authors.initials: V
authors.lastname: Cadierno
mesh_terms: D000480:Alkynes / Q000737:chemistry; D001688:Biological Products / Q000138:chemical synthesis*; D002236:Carbohydrate Conformation; D002384:Catalysis; D002625:Chemistry, Organic / Q000379:methods*; D003374:Coumarins / Q000138:chemical synthesis*; D018360:Crystallography, X-Ray; D005296:Ferrous Compounds / Q000737:chemistry; D006358:Hot Temperature; D009682:Magnetic Resonance Spectroscopy; D000075163:Metallocenes; D008872:Microwaves; D009942:Organometallic Compounds / Q000138:chemical synthesis*; D010720:Phosphines / Q000737:chemistry; D020005:Propanols / Q000737:chemistry; D012428:Ruthenium / Q000737:chemistry; D014269:Trifluoroacetic Acid / Q000737:chemistry
chemical_list: D000480:Alkynes; D001688:Biological Products; D003374:Coumarins; D005296:Ferrous Compounds; D000075163:Metallocenes; D009942:Organometallic Compounds; D010720:Phosphines; D020005:Propanols; D012428:Ruthenium; D014269:Trifluoroacetic Acid; C028255:propargyl alcohol; C519379:1,1'-bis(diphenylphosphino)ferrocene