title: Surgical outcomes for gastric cancer of a single institute in southeast China.
abstract: BACKGROUND
  In recent years, with social and economic development and lifestyle changes, the incidence of gastric cancer as well as the surgical results and prognoses of patients with gastric cancer have changed significantly in southeast China.
  
  
  METHODS
  A total of 1,451 patients were divided into 2 groups according to admission time periods. Trends in clinicopathologic characteristics and operative outcomes of these patients were analyzed retrospectively.
  
  
  RESULTS
  The numbers of old and young patients were significantly increased in period 2 compared with period 1. Tumors located in the proximal stomach increased from 20.26% to 36.83%. The incidence of early gastric cancer was significantly increased from period 1 to period 2. Lymph node metastasis was seen more prevalently in period 2 than in period 1. The rate of operation-related major complications decreased from 5.23% to 1.43%. Operative mortality was .49% in period 1 and .24% in period 2. The 5-year survival rate increased from 38.40% to 53.99%.
  
  
  CONCLUSIONS
  Early diagnosis, standardized surgical treatment including pertinent lymph node dissection, and better perioperative care notably improve the outcomes of patients with gastric cancer.
authors.affiliation: Department of General Surgery, First Affiliated Hospital of Nanjing Medical University, China.
authors.forename: Yong-Bin
authors.initials: YB
authors.lastname: Ding
authors.forename: Tian-Song
authors.initials: TS
authors.lastname: Xia
authors.forename: Jin-Dao
authors.initials: JD
authors.lastname: Wu
authors.forename: Guo-Yu
authors.initials: GY
authors.lastname: Chen
authors.forename: Shui
authors.initials: S
authors.lastname: Wang
authors.forename: Jian-Guo
authors.initials: JG
authors.lastname: Xia
mesh_terms: D000230:Adenocarcinoma / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D002681:China; D005260:Female; D005500:Follow-Up Studies; D005743:Gastrectomy / Q000639:trends*; D006801:Humans; D015994:Incidence; D053208:Kaplan-Meier Estimate; D008197:Lymph Node Excision / Q000639:trends; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011183:Postoperative Complications / Q000453:epidemiology; D012008:Recurrence; D012189:Retrospective Studies; D013274:Stomach Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D015996:Survival Rate; D016896:Treatment Outcome