title: Anti-müllerian hormone is the best predictor of poor response in ICSI cycles of patients with endometriosis.
abstract: OBJECTIVE
  To correlate ovarian reserve (OR) markers with response in assisted reproduction techniques (ART) and determine their ability to predict poor response among patients with endometriosis (EDT).
  
  
  METHODS
  We evaluated ART cycles of 27 women with EDT and 50 with exclusive male factor. Basal follicle stimulating hormone (FSH) and anti-müllerian hormone (AMH) levels were determined. Ovarian response to gonadotropin stimulation was assessed and correlation coefficients calculated between the variables and reserve markers. Areas under the curve (AUC) determined ability of tests to predict poor response.
  
  
  RESULTS
  AMH was significantly correlated with response in both groups and it was the only marker with significant discriminative capacity to predict poor response among EDT (AUC = 0.842; 95% CI: 0.651-0.952) and control group (AUC = 0.869; 95% CI: 0.743-0.947).
  
  
  CONCLUSIONS
  Infertile patients with endometriosis can benefit from the pre-therapeutic assessment of OR markers. However, regardless of disease presence, only AMH predicts poor response to stimulus.
authors.affiliation: Sector of Human Reproduction, Department of Gynecology and Obstetrics, Faculty of Medicine of Ribeirão Preto, University of São Paulo, Ribeirão Preto, São Paulo, Brazil. bruno@genesis.med.br
authors.forename: B Ramalho
authors.initials: BR
authors.lastname: de Carvalho
authors.forename: A C Japur de Sá
authors.initials: AC
authors.lastname: Rosa-e-Silva
authors.forename: J C
authors.initials: JC
authors.lastname: Rosa-e-Silva
authors.forename: R M
authors.initials: RM
authors.lastname: dos Reis
authors.forename: R A
authors.initials: RA
authors.lastname: Ferriani
authors.forename: M F Silva
authors.initials: MF
authors.lastname: de Sá
mesh_terms: D054304:Anti-Mullerian Hormone / Q000097:blood*; D004715:Endometriosis / Q000097:blood* / Q000150:complications / Q000628:therapy; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood*; D006801:Humans; D007247:Infertility, Female / Q000209:etiology; D007248:Infertility, Male; D008297:Male; D010053:Ovary / Q000502:physiology*; D010062:Ovulation Induction / Q000379:methods*; D012372:ROC Curve; D020554:Sperm Injections, Intracytoplasmic / Q000379:methods*
chemical_list: D054304:Anti-Mullerian Hormone; D005640:Follicle Stimulating Hormone