title: Plants grow on brassinosteroids.
abstract: Brassinosteroids (BRs) are plant steroid hormones known mainly for promoting organ growth through their combined effect on cell expansion and division. In addition, BRs regulate a broad spectrum of plant developmental and physiological responses, including plant architecture, vascular differentiation, male fertility, flowering, senescence, photomorphogenesis and tolerance to biotic and abiotic stresses. Recently, a complete core BR signaling pathway was defined in which BR signals are conveyed from the cell surface to the nucleus through sequential signaling modules. A major challenge now is to understand precisely how this signaling pathway controls the different BR-regulated actions. The current identification of direct targets of BRASSINAZOLE-RESISTANT1 (BRZ1) and BR-INSENSITIVE-EMS-SUPPRESSOR1 (BES1)/BZR2 transcription factors suggests that BR signaling pathway controls growth and interacts with other signaling pathways mainly at the transcriptional level.
authors.affiliation: Department of Plant Systems Biology, VIB, Technologiepark 927, 9052 Gent, Belgium.
authors.forename: Gustavo E
authors.initials: GE
authors.lastname: Gudesblat
authors.forename: Eugenia
authors.initials: E
authors.lastname: Russinova
mesh_terms: D029681:Arabidopsis Proteins / Q000378:metabolism; D060406:Brassinosteroids / Q000378:metabolism*; D004268:DNA-Binding Proteins; D009687:Nuclear Proteins / Q000378:metabolism; D063245:Plant Development; D010937:Plant Growth Regulators / Q000378:metabolism*; D010944:Plants / Q000378:metabolism; D015398:Signal Transduction; D014157:Transcription Factors / Q000378:metabolism
chemical_list: D029681:Arabidopsis Proteins; C454444:BZR1 protein, Arabidopsis; D060406:Brassinosteroids; D004268:DNA-Binding Proteins; D009687:Nuclear Proteins; D010937:Plant Growth Regulators; D014157:Transcription Factors