title: Gemcitabine induced myositis in patients with pancreatic cancer: case reports and topic review.
abstract: Gemcitabine potential myotoxicity has been described in several cases of radiation recall and in patients treated with gemcitabine alone or in combination with other chemotherapy agents.  We report two cases of gemcitabine related myositis identified at our institution, and perform a literature review of cases which meet the criteria for gemcitabine induced myositis associated to either radiation therapy or chemotherapy alone.
authors.affiliation: Department of Neurology, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.
authors.forename: Elena
authors.initials: E
authors.lastname: Pentsova
authors.forename: Anli
authors.initials: A
authors.lastname: Liu
authors.forename: Marc
authors.initials: M
authors.lastname: Rosenblum
authors.forename: Eileen
authors.initials: E
authors.lastname: O'Reilly
authors.forename: Xi
authors.initials: X
authors.lastname: Chen
authors.forename: Adília
authors.initials: A
authors.lastname: Hormigo
mesh_terms: D000230:Adenocarcinoma / Q000150:complications* / Q000188:drug therapy* / Q000473:pathology; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D000964:Antimetabolites, Antineoplastic / Q000009:adverse effects* / Q000627:therapeutic use; D003841:Deoxycytidine / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000627:therapeutic use; D003907:Dexamethasone / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D018482:Muscle, Skeletal / Q000473:pathology; D009220:Myositis / Q000139:chemically induced* / Q000473:pathology; D010190:Pancreatic Neoplasms / Q000150:complications* / Q000188:drug therapy* / Q000473:pathology; D011878:Radiotherapy / Q000009:adverse effects; D013848:Thigh / Q000473:pathology; D000093542:Gemcitabine
chemical_list: D000893:Anti-Inflammatory Agents; D000964:Antimetabolites, Antineoplastic; D003841:Deoxycytidine; D003907:Dexamethasone; D000093542:Gemcitabine