title: Hydrogen bonding mediated enantioselective organocatalysis in brine: significant rate acceleration and enhanced stereoselectivity in enantioselective Michael addition reactions of 1,3-dicarbonyls to β-nitroolefins.
abstract: Brine provides remarkable rate acceleration and a higher level of stereoselectivity over organic solvents, due to the hydrophobic hydration effect, in the enantioselective Michael addition reactions of 1,3-dicarbonyls to β-nitroolefins using chiral H-donors as organocatalysts.
authors.affiliation: Department of Chemistry, Sungkyunkwan University, 300 Cheoncheon, Jangan, Suwon, Gyeonggi, 440-746, Korea.
authors.forename: Han Yong
authors.initials: HY
authors.lastname: Bae
authors.forename: Surajit
authors.initials: S
authors.lastname: Some
authors.forename: Joong Suk
authors.initials: JS
authors.lastname: Oh
authors.forename: Yong Seop
authors.initials: YS
authors.lastname: Lee
authors.forename: Choong Eui
authors.initials: CE
authors.lastname: Song
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D002384:Catalysis; D006860:Hydrogen Bonding; D012492:Salts / Q000737:chemistry*; D013237:Stereoisomerism; D013379:Substrate Specificity; D014867:Water / Q000737:chemistry
chemical_list: D000475:Alkenes; D012492:Salts; C017082:brine; D014867:Water