title: Exhaled breath volatile alterations in pregnancy assessed with electronic nose.
abstract: BACKGROUND
  Pregnancy-linked accelerated metabolism and oxidative stress may alter the exhaled volatile compound pattern ("breathprint"). Electronic noses can distinguish "breathprints" associated with different disorders.
  
  
  OBJECTIVE
  This is the first study assessing alterations in "breathprint" during gestation.
  
  
  METHODS
  130 women participated in our study (78 pregnant vs. 52 non-pregnant). Breath samples were processed by an electronic nose and analyzed using principal component analysis.
  
  
  RESULTS
  Significant differences were found in exhaled breath pattern between pregnant and non-pregnant women (p = 0.001).
  
  
  CONCLUSIONS
  Pregnancy-induced changes in exhaled gases need to be considered when pregnant women with respiratory disorders carry out breath tests.
authors.affiliation: Department of Pulmonology, Semmelweis University , Budapest , Hungary.
authors.forename: Andras
authors.initials: A
authors.lastname: Bikov
authors.forename: Judit
authors.initials: J
authors.lastname: Pako
authors.forename: Dorottya
authors.initials: D
authors.lastname: Kovacs
authors.forename: Lilla
authors.initials: L
authors.lastname: Tamasi
authors.forename: Zsofia
authors.initials: Z
authors.lastname: Lazar
authors.forename: Janos
authors.initials: J
authors.lastname: Rigo
authors.forename: Gyorgy
authors.initials: G
authors.lastname: Losonczy
authors.forename: Ildiko
authors.initials: I
authors.lastname: Horvath
mesh_terms: D000328:Adult; D001944:Breath Tests / Q000295:instrumentation / Q000379:methods; D016022:Case-Control Studies; D002623:Chemistry Techniques, Analytical / Q000379:methods*; D019411:Clinical Laboratory Techniques / Q000379:methods*; D003430:Cross-Sectional Studies; D004581:Electronics / Q000379:methods*; D045853:Exhalation / Q000502:physiology*; D005260:Female; D006801:Humans; D006814:Hungary; D018384:Oxidative Stress / Q000502:physiology; D011247:Pregnancy; D025341:Principal Component Analysis / Q000379:methods