title: Laparoscopy within a fast-track program enhances the short-term results after elective surgery for resectable colorectal cancer.
abstract: BACKGROUND
  Whether laparoscopic colorectal resection improved recovery within an enhanced recovery program was investigated.
  
  
  METHODS
  This study was designed as a query of a prospectively maintained colorectal database to identify 350 patients who underwent elective colorectal resection with primary anastomosis for colorectal cancer between January 1, 2005 and December 31, 2009. Patients were categorized into two groups (laparoscopic and open resection), and demographic, treatment, and outcome variables were independently reviewed for accuracy. A detailed fast-track protocol was prepared and distributed to all patients, department doctors, and nurses to standardize the treatment.
  
  
  RESULTS
  A total of 209 patients underwent laparoscopic-assisted colorectal resection, and 141 had open surgery. There was no difference between the two groups in terms of age, sex, BMI, ASA, comorbidity, previous abdominal surgery, preoperative chemoradiotherapy, cancer site, and AJCC 2002 staging. Twenty-three patients in the laparoscopic group required conversion to an open procedure due to hemorrhage, tumor extension, or technical difficulties. Laparoscopic patients had earlier tolerance of diet, bowel movement, flatus and stool canalization, mobilization, suction drain removal, and interruption of analgesic drug administration. Length of postoperative stay was shorter (4 vs. 7 days, p = 0.0004) and fewer postoperative nonsurgical complications (3 vs. 13% p = 0.009) were registered for the laparoscopic group.
  
  
  CONCLUSIONS
  This study suggests that within an enhanced recovery program, laparoscopic resection may provide the best short-term clinical outcomes for patients with resectable colorectal cancer.
authors.affiliation: Department of General Surgery, Misericordia and Dolce Hospital, Piazza dell'Ospedale 5, 59100 Prato (Po), Italy. fferoci@yahoo.it
authors.forename: Francesco
authors.initials: F
authors.lastname: Feroci
authors.forename: Katrin C
authors.initials: KC
authors.lastname: Kröning
authors.forename: Elisa
authors.initials: E
authors.lastname: Lenzi
authors.forename: Luca
authors.initials: L
authors.lastname: Moraldi
authors.forename: Stefano
authors.initials: S
authors.lastname: Cantafio
authors.forename: Marco
authors.initials: M
authors.lastname: Scatizzi
mesh_terms: D000230:Adenocarcinoma / Q000534:rehabilitation / Q000601:surgery*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003082:Colectomy / Q000379:methods / Q000534:rehabilitation / Q000706:statistics & numerical data; D015179:Colorectal Neoplasms / Q000534:rehabilitation / Q000601:surgery*; D016208:Databases, Factual / Q000706:statistics & numerical data; D017558:Elective Surgical Procedures / Q000534:rehabilitation* / Q000706:statistics & numerical data; D005260:Female; D006801:Humans; D007081:Ileostomy / Q000379:methods / Q000534:rehabilitation / Q000706:statistics & numerical data; D007431:Intraoperative Complications / Q000453:epidemiology / Q000517:prevention & control; D010535:Laparoscopy / Q000379:methods / Q000534:rehabilitation* / Q000706:statistics & numerical data; D007813:Laparotomy / Q000379:methods / Q000534:rehabilitation / Q000706:statistics & numerical data; D007902:Length of Stay / Q000706:statistics & numerical data; D008297:Male; D008875:Middle Aged; D020360:Neoadjuvant Therapy; D011182:Postoperative Care / Q000379:methods*; D011183:Postoperative Complications / Q000453:epidemiology / Q000517:prevention & control; D011300:Preoperative Care / Q000379:methods*; D015397:Program Evaluation; D020127:Recovery of Function; D012189:Retrospective Studies; D016896:Treatment Outcome