title: Acid-base jointly promoted copper(I)-catalyzed azide-alkyne cycloaddition.
abstract: In this novel acid-base jointly promoted CuAAC, the combination of CuI/DIPEA/HOAc was developed as a highly efficient catalytic system. The functions of DIPEA and HOAc have been assigned, and HOAc was recognized to accelerate the conversions of the C-Cu bond-containing intermediates and buffer the basicity of DIPEA. As a result, all drawbacks occurring in the popular catalytic system CuI/NR(3) were overcome easily.
authors.affiliation: Department of Chemistry, Tsinghua University, Beijing 100084, P. R. China.
authors.forename: Changwei
authors.initials: C
authors.lastname: Shao
authors.forename: Xinyan
authors.initials: X
authors.lastname: Wang
authors.forename: Qun
authors.initials: Q
authors.lastname: Zhang
authors.forename: Sheng
authors.initials: S
authors.lastname: Luo
authors.forename: Jichen
authors.initials: J
authors.lastname: Zhao
authors.forename: Yuefei
authors.initials: Y
authors.lastname: Hu