title: Moxifloxacin prophylaxis for chemoembolization or embolization in patients with previous biliary interventions: a pilot study.
abstract: OBJECTIVE
  Abscess formation is a common serious adverse event after intraarterial therapy for hepatic malignancy in patients with colonized bile ducts. The combination of antibiotic prophylaxis and bowel preparation has been used to prevent hepatic abscess. We describe our outcomes with moxifloxacin prophylaxis alone without bowel preparation.
  
  
  CONCLUSIONS
  Ten patients underwent 25 procedures and were followed for a median of 250 days. No abscesses developed. Our results suggest moxifloxacin alone may suffice for prophylaxis.
authors.affiliation: Department of Radiology, Division of Interventional Radiology, Thomas Jefferson University, 132 S 10th St, Ste 766 Main Bldg, Philadelphia, PA 19107, USA.
authors.forename: Waseem
authors.initials: W
authors.lastname: Khan
authors.forename: Kevin L
authors.initials: KL
authors.lastname: Sullivan
authors.forename: Jeffrey W
authors.initials: JW
authors.lastname: McCann
authors.forename: Carin F
authors.initials: CF
authors.lastname: Gonsalves
authors.forename: Takami
authors.initials: T
authors.lastname: Sato
authors.forename: David J
authors.initials: DJ
authors.lastname: Eschelman
authors.forename: Daniel B
authors.initials: DB
authors.lastname: Brown
mesh_terms: D000890:Anti-Infective Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D019072:Antibiotic Prophylaxis; D000970:Antineoplastic Agents / Q000008:administration & dosage; D001372:Aza Compounds / Q000008:administration & dosage / Q000627:therapeutic use*; D001660:Biliary Tract Diseases / Q000628:therapy; D016022:Case-Control Studies; D016461:Chemoembolization, Therapeutic; D004621:Embolization, Therapeutic / Q000379:methods*; D004998:Ethiodized Oil / Q000008:administration & dosage; D005260:Female; D024841:Fluoroquinolones; D006801:Humans; D008100:Liver Abscess / Q000517:prevention & control*; D008113:Liver Neoplasms / Q000628:therapy*; D008297:Male; D000077266:Moxifloxacin; D010865:Pilot Projects; D011804:Quinolines / Q000008:administration & dosage / Q000627:therapeutic use*; D015641:Radiography, Interventional; D012189:Retrospective Studies; D012307:Risk Factors
chemical_list: D000890:Anti-Infective Agents; D000970:Antineoplastic Agents; D001372:Aza Compounds; D024841:Fluoroquinolones; D011804:Quinolines; D004998:Ethiodized Oil; D000077266:Moxifloxacin