title: Selective determination of arbutin in cosmetic products through online derivatization followed by disposable electrochemical sensor.
abstract: An online derivatization followed by a disposable electrochemical sensor was used for the determination of arbutin (AR) in cosmetic products. The AR was chemically oxidized by MnO2 and subsequently reduced at inexpensive screen-printed carbon electrodes using a low detection potential which improved the selectivity of the method. The effects of various parameters, such as solution pH, detection potential, and flow rate of the mobile phase, were studied in detail. Under optimal conditions [pH 1.6 (0.1 M H3PO4), detection potential 0.0 V (versus Ag/AgCl), flow rate 0.6 mL/min], the linear range for AR was 0.1-1500 ppm (r2 = 0.999) with LOD of 30.06 ppb (S/N = 3). The practical application of the proposed method was demonstrated by the determination of arbutin concentration in commercial cosmetic products.
authors.affiliation: National Chung Hsing University, Department of Chemistry, Taichung 402, Taiwan.
authors.forename: Jyh-Myng
authors.initials: JM
authors.lastname: Zen
authors.forename: Hsueh-Hui
authors.initials: HH
authors.lastname: Yang
authors.forename: Mei-Hsin
authors.initials: MH
authors.lastname: Chiu
authors.forename: Chao-Hsun
authors.initials: CH
authors.lastname: Yang
authors.forename: Ying
authors.initials: Y
authors.lastname: Shih
mesh_terms: D001104:Arbutin / Q000737:chemistry*; D003358:Cosmetics / Q000737:chemistry*; D004563:Electrochemistry / Q000295:instrumentation* / Q000379:methods*; D017895:Manganese Compounds / Q000737:chemistry; D010084:Oxidation-Reduction; D010087:Oxides / Q000737:chemistry
chemical_list: D003358:Cosmetics; D017895:Manganese Compounds; D010087:Oxides; D001104:Arbutin; C016552:manganese dioxide