title: A diagnostic challenge: acute generalized exanthematous pustulosis or pustular psoriasis due to terbinafine.
abstract: A 72-year-old man developed a generalized erythematous pustular eruption 11 weeks after commencing terbinafine. Clinically and histologically, the appearance was that of acute generalized exanthematous pustulosis (AGEP), and the disease was managed with topical preparations. Initial improvement was marred by relapse of acute pustulosis, now more in keeping with terbinafine-induced pustular psoriasis (PP), which was successfully treated with acitretin. This case highlights the difficulty of differentiating between AGEP and PP.
authors.affiliation: Birmingham Skin Centre, City Hospital, Birmingham,UK.
authors.forename: L
authors.initials: L
authors.lastname: Duckworth
authors.forename: M B
authors.initials: MB
authors.lastname: Maheshwari
authors.forename: M A
authors.initials: MA
authors.lastname: Thomson
mesh_terms: D056150:Acute Generalized Exanthematous Pustulosis / Q000139:chemically induced / Q000175:diagnosis*; D000368:Aged; D000935:Antifungal Agents / Q000009:adverse effects; D003937:Diagnosis, Differential; D003875:Drug Eruptions / Q000175:diagnosis*; D006801:Humans; D008297:Male; D009281:Naphthalenes / Q000009:adverse effects; D011565:Psoriasis / Q000139:chemically induced / Q000175:diagnosis*; D012872:Skin Diseases, Vesiculobullous / Q000139:chemically induced / Q000175:diagnosis*; D000077291:Terbinafine
chemical_list: D000935:Antifungal Agents; D009281:Naphthalenes; D000077291:Terbinafine