title: Cluster of symptoms in women with breast cancer treated with curative intent.
abstract: OBJECTIVE
  The purpose of this study is to verify that there is a cluster of symptoms in women with breast cancer who were treated with curative intent and are free of disease.
  
  
  METHODS
  One hundred and thirty-eight patients were recruited from the Mastology Department of Hospital A.C. Camargo with breast cancer, who have been treated with curative intent and concluded adjuvant chemotherapy 3-24 months prior who may or may not be using hormone therapy. The characterization of the sample was made through descriptive statistics (mean, standard deviation, median, and percentage). For evaluation of the cluster of symptoms, the following were used: Pearson correlation coefficient among the scales of Profile of Mood States, EORTC-QLQ-C30, and EORTC-BR23 and a factor analysis with principal components analysis with promax rotation (oblique). For the extraction of factors, an eigenvalue of 1 was considered, and to evaluate the permanence of symptom factor, a load greater than 0.40 was considered. Statistical significance was defined as p value <0.05.
  
  
  RESULTS
  Through factor analysis of data, three distinct groupings were observed. Factor 1 corresponds to the psychoemotional symptoms and grouped as depression, confusion, anger, tension, fatigue, and breast symptoms. Factor 2 corresponds to physical symptoms, which include pain, dyspnea, arm symptoms, and insomnia. Finally, factor 3 corresponds to gastrointestinal symptoms (inappetence, diarrhea, nausea, and vomiting).
  
  
  CONCLUSIONS
  Through the data presented, the cluster of symptoms could be verified in women with breast cancer who were treated with curative intent and free of disease.
authors.affiliation: Antonio Prudente Foundation, São Paulo, Brazil. contato@alexandrelevangelista.com.br
authors.forename: Alexandre Lopes
authors.initials: AL
authors.lastname: Evangelista
authors.forename: Erika Maria Monteiro
authors.initials: EM
authors.lastname: Santos
mesh_terms: D000328:Adult; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D001943:Breast Neoplasms / Q000473:pathology* / Q000523:psychology / Q000628:therapy; D017024:Chemotherapy, Adjuvant / Q000379:methods; D016000:Cluster Analysis; D005163:Factor Analysis, Statistical; D005260:Female; D006801:Humans; D008875:Middle Aged; D011788:Quality of Life
chemical_list: D000970:Antineoplastic Agents