title: Yolk sac tumor in a patient with transverse testicular ectopia.
abstract: Transverse testicular ectopia (TTE) is a rare anomaly in which both testes descend through a single inguinal canal. We report a case of yolk sac tumor in the ectopic testis of a patient with TTE. A 24-year-old man presented to our hospital with a left inguinal-mass, right cryptorchidism and elevated alpha-fetoprotein (AFP). A left herniotomy 3 years earlier demonstrated both testes in the left scrotum, one above another positionally. Four months ago, a left scrotal mass appeared and radical orchiectomy of both testes revealed testicular yolk sac tumor of the ectopic testis. An enlarging left inguinal-mass appeared 2 months ago and he was referred to our hospital. Laboratory data showed an elevation of AFP (245.5 ng/ml) and a 46 XY karyotype. He underwent bilateral retroperitoneal lymph node dissection and simultaneous left inguinal mass dissection. Histopathologic examination revealed a diagnosis of recurrent yolk sac tumor in the left inguinal mass. The retroperitoneal lymph node was not enlarged and, on histopathology, was not involved. The patient has now been followed up for 8 months without evidence of biochemical or radiological recurrence.
authors.affiliation: Department of Urology, Fudan University Shanghai Cancer Center, China.
authors.forename: Yi-Ping
authors.initials: YP
authors.lastname: Zhu
authors.forename: Shi-Lin
authors.initials: SL
authors.lastname: Zhang
authors.forename: Ding-Wei
authors.initials: DW
authors.lastname: Ye
authors.forename: Guo-hai
authors.initials: GH
authors.lastname: Shi
authors.forename: Wen-jun
authors.initials: WJ
authors.lastname: Xiao
mesh_terms: D003456:Cryptorchidism / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D003937:Diagnosis, Differential; D018240:Endodermal Sinus Tumor / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D009367:Neoplasm Staging / Q000379:methods; D009919:Orchiectomy / Q000379:methods; D013736:Testicular Neoplasms / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery; D013737:Testis / Q000002:abnormalities*; D055815:Young Adult