title: Functional-food constituents in the fruiting bodies of Stropharia rugosoannulata.
abstract: Nine compounds (1-9) were isolated from the fruiting bodies of Stropharia rugosoannulata. Compounds 1-5, 8, and 9 suppressed the formation of osteoclast. Compounds 2 and 5 showed anti-fungal activity, and their MIC were 250 µM and 500 µM respectively. Compounds 2-6 showed inhibitory effects on thapsigargin toxicity.
authors.affiliation: Graduate School of Science and Technology, Shizuoka University, Suruga-ku, Shizuoka, Japan.
authors.forename: Jing
authors.initials: J
authors.lastname: Wu
authors.forename: Keiji
authors.initials: K
authors.lastname: Fushimi
authors.forename: Shinji
authors.initials: S
authors.lastname: Tokuyama
authors.forename: Masato
authors.initials: M
authors.lastname: Ohno
authors.forename: Takaaki
authors.initials: T
authors.lastname: Miwa
authors.forename: Tomoyuki
authors.initials: T
authors.lastname: Koyama
authors.forename: Kazunaga
authors.initials: K
authors.lastname: Yazawa
authors.forename: Kaoru
authors.initials: K
authors.lastname: Nagai
authors.forename: Tetsuo
authors.initials: T
authors.lastname: Matsumoto
authors.forename: Hirofumi
authors.initials: H
authors.lastname: Hirai
authors.forename: Hirokazu
authors.initials: H
authors.lastname: Kawagishi
mesh_terms: D000363:Agaricales / Q000737:chemistry*; D000935:Antifungal Agents / Q000737:chemistry / Q000494:pharmacology*; D001688:Biological Products / Q000737:chemistry / Q000494:pharmacology*; D001862:Bone Resorption / Q000503:physiopathology / Q000517:prevention & control*; D016923:Cell Death / Q000187:drug effects; D002470:Cell Survival / Q000187:drug effects; D002855:Chromatography, Thin Layer; D045424:Complex Mixtures / Q000737:chemistry; D004721:Endoplasmic Reticulum / Q000187:drug effects / Q000378:metabolism; D004791:Enzyme Inhibitors / Q000737:chemistry / Q000494:pharmacology*; D048690:Fruiting Bodies, Fungal / Q000737:chemistry; D055951:Functional Food / Q000032:analysis; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D009181:Mycoses / Q000188:drug therapy / Q000382:microbiology; D010010:Osteoclasts / Q000166:cytology / Q000187:drug effects*; D012997:Solvents; D019284:Thapsigargin / Q000737:chemistry / Q000494:pharmacology*
chemical_list: D000935:Antifungal Agents; D001688:Biological Products; D045424:Complex Mixtures; D004791:Enzyme Inhibitors; D012997:Solvents; D019284:Thapsigargin