title: A heterodimeric glucuronide prodrug for cancer tritherapy: the double role of the chemical amplifier.
authors.affiliation: Laboratoire de Synthèse et Réactivité des Substances Naturelles, UMR-CNRS 6514, Université de Poitiers, 4 rue Michel Brunet, BP 633, 86022 Poitiers, France.
authors.forename: Marion
authors.initials: M
authors.lastname: Grinda
authors.forename: Jonathan
authors.initials: J
authors.lastname: Clarhaut
authors.forename: Isabelle
authors.initials: I
authors.lastname: Tranoy-Opalinski
authors.forename: Brigitte
authors.initials: B
authors.lastname: Renoux
authors.forename: Arnaud
authors.initials: A
authors.lastname: Monvoisin
authors.forename: Laurent
authors.initials: L
authors.lastname: Cronier
authors.forename: Sébastien
authors.initials: S
authors.lastname: Papot
mesh_terms: D000970:Antineoplastic Agents / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D001549:Benzamides / Q000138:chemical synthesis / Q000737:chemistry / Q000633:toxicity; D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects; D019281:Dimerization; D004317:Doxorubicin / Q000031:analogs & derivatives / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology / Q000633:toxicity; D004354:Drug Screening Assays, Antitumor; D004357:Drug Synergism; D005966:Glucuronidase / Q000378:metabolism; D020719:Glucuronides / Q000737:chemistry*; D006801:Humans; D009369:Neoplasms; D011355:Prodrugs / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D011725:Pyridines / Q000138:chemical synthesis / Q000737:chemistry / Q000633:toxicity
chemical_list: D000970:Antineoplastic Agents; D001549:Benzamides; D020719:Glucuronides; D011355:Prodrugs; D011725:Pyridines; C118739:entinostat; D004317:Doxorubicin; D005966:Glucuronidase