title: Scalable fabrication of immunosensors based on carbon nanotube polymer composites.
abstract: In this work we present the fabrication and characterization of immunosensors based on polystyrene (PS)-multiwalled carbon nanotube (MWCNT) composites. The electrochemical properties of the sensors have been investigated and show that the surface area is increased upon addition of the MWCNT-PS layer. Furthermore, a plasma activation process is used to partially remove the PS and expose the MWCNTs. This results in a huge increase in the electrochemical area and opens up the possibility of binding biomolecules to the MWCNT wall. The MWCNTs have been functionalized covalently with a model antibody (rabbit IgG). The biosensors have been tested using amperometric techniques and show detection limits comparable to standard techniques such as ELISA.
authors.affiliation: Institut Català de Nanotecnologia, Campus Universitat Autónoma de Barcelona, 08193 Bellaterra, Spain.
authors.forename: Ernest
authors.initials: E
authors.lastname: Mendoza
authors.forename: Jahir
authors.initials: J
authors.lastname: Orozco
authors.forename: Cecilia
authors.initials: C
authors.lastname: Jiménez-Jorquera
authors.forename: Ana B
authors.initials: AB
authors.lastname: González-Guerrero
authors.forename: Ana
authors.initials: A
authors.lastname: Calle
authors.forename: Laura M
authors.initials: LM
authors.lastname: Lechuga
authors.forename: César
authors.initials: C
authors.lastname: Fernández-Sánchez