title: New simvastatin dosing recommendations.
mesh_terms: D000818:Animals; D051544:Cytochrome P-450 CYP3A / Q000378:metabolism; D065692:Cytochrome P-450 CYP3A Inhibitors; D004305:Dose-Response Relationship, Drug; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000008:administration & dosage / Q000009:adverse effects; D009135:Muscular Diseases / Q000139:chemically induced* / Q000201:enzymology / Q000517:prevention & control; D016032:Randomized Controlled Trials as Topic / Q000379:methods; D019821:Simvastatin / Q000008:administration & dosage* / Q000009:adverse effects*; D014481:United States; D014486:United States Food and Drug Administration / Q000592:standards* / Q000639:trends
chemical_list: D065692:Cytochrome P-450 CYP3A Inhibitors; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D019821:Simvastatin; D051544:Cytochrome P-450 CYP3A; C510163:CYP3A4 protein, human