title: Highly stereoselective synthesis of tetrasubstituted alkenes via hydroamination of alkynes and C-H acetoxylation.
abstract: A novel reaction including the sequence of hydroamination of alkynes and subsequent oxidative C-H bond functionalization has been developed in the presence of diacetoxyiodobenzene (DIB). The method allows us to synthesize a wide range of tetrasubstituted (E)-alkenes and provides a potential method to construct densely functionalized carbonyl compounds.
authors.affiliation: School of Chemistry and Life Science, Guangdong University of Petrochemical Technology, 139 Guangdu Two Road, Maoming 525000, PR China. lwb409@yahoo.com.cn
authors.forename: Weibing
authors.initials: W
authors.lastname: Liu
authors.forename: Cui
authors.initials: C
authors.lastname: Chen
authors.forename: Qing
authors.initials: Q
authors.lastname: Zhang
mesh_terms: D000475:Alkenes / Q000138:chemical synthesis* / Q000737:chemistry; D000480:Alkynes / Q000737:chemistry*; D000586:Amination; D060326:Chemistry Techniques, Synthetic; D007462:Iodobenzenes / Q000737:chemistry*; D015394:Molecular Structure; D010084:Oxidation-Reduction; D013237:Stereoisomerism
chemical_list: D000475:Alkenes; D000480:Alkynes; D007462:Iodobenzenes