title: Acromegaly and pregnancy.
abstract: In women with acromegaly due to growth hormone (GH)-secreting pituitary adenomas, the occurrence of pregnancy warrants consideration of: (1) the consequences of pregnancy on the pituitary adenoma including the tumor syndrome and GH/IGF-1 secretion, (2) the consequence of GH/IGF-1 hypersecretion on the pregnant woman and the fetus, (3) the consequences of pituitary surgery and medical treatment (dopamine agonists, somatostatin analogs, GH receptor antagonist) on the pregnant woman and the developing fetus.
authors.affiliation: Pôle cardiovasculaire et métabolique, service d'endocrinologie, maladies métaboliques et nutrition, CHU Rangueil-Larrey, 24, chemin de Pouvourville, TSA 30030, 31059 Toulouse cedex 9, France. Electronic address: caron.p@chu-toulouse.fr.
authors.forename: P
authors.initials: P
authors.lastname: Caron
mesh_terms: D000172:Acromegaly / Q000150:complications* / Q000503:physiopathology / Q000628:therapy; D005260:Female; D005333:Fetus / Q000503:physiopathology; D049912:Growth Hormone-Secreting Pituitary Adenoma / Q000150:complications / Q000378:metabolism / Q000503:physiopathology; D006727:Hormone Antagonists / Q000627:therapeutic use; D006801:Humans; D007334:Insulin-Like Growth Factor I / Q000378:metabolism; D008431:Maternal-Fetal Exchange; D010053:Ovary / Q000503:physiopathology; D010902:Pituitary Gland / Q000503:physiopathology; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy / Q000503:physiopathology* / Q000601:surgery; D011252:Pregnancy Complications, Neoplastic
chemical_list: D006727:Hormone Antagonists; D007334:Insulin-Like Growth Factor I