title: Trastuzumab (herceptin).
abstract: Herceptin (trastuzumab) is a human monoclonal antibody that interferes with the HER2 receptor. It is currently the only FDA-approved therapeutic antibody for HER2-positive breast cancer. This article will present the mechanism at action as well as the clinical role at this monoclonal antibody.
authors.affiliation: Division of Neuroradiology, Department of Radiology, University of Michigan Health System, Ann Arbor, USA. gemmete@med.umich.edu
authors.forename: J J
authors.initials: JJ
authors.lastname: Gemmete
authors.forename: S K
authors.initials: SK
authors.lastname: Mukherji
mesh_terms: D061067:Antibodies, Monoclonal, Humanized / Q000627:therapeutic use*; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D001943:Breast Neoplasms / Q000188:drug therapy*; D005260:Female; D006801:Humans; D000068878:Trastuzumab
chemical_list: D061067:Antibodies, Monoclonal, Humanized; D000970:Antineoplastic Agents; D000068878:Trastuzumab