title: The neural circadian system of mammals.
abstract: Humans and other mammals exhibit a remarkable array of cyclical changes in physiology and behaviour. These are often synchronized to the changing environmental light-dark cycle and persist in constant conditions. Such circadian rhythms are controlled by an endogenous clock, located in the suprachiasmatic nuclei of the hypothalamus. This structure and its cells have unique properties, and some of these are reviewed to highlight how this central clock controls and sculpts our daily activities.
authors.affiliation: AV Hill Building, University of Manchester, Oxford Road, U.K. hugh.d.piggins@manchester.ac.uk
authors.forename: Hugh D
authors.initials: HD
authors.lastname: Piggins
authors.forename: Clare
authors.initials: C
authors.lastname: Guilding
mesh_terms: D000200:Action Potentials / Q000502:physiology; D000818:Animals; D001519:Behavior / Q000502:physiology*; D001683:Biological Clocks / Q000502:physiology*; D002940:Circadian Rhythm / Q000502:physiology*; D006801:Humans; D007031:Hypothalamus / Q000378:metabolism / Q000502:physiology; D009474:Neurons / Q000378:metabolism / Q000502:physiology*; D017440:Photoperiod; D013493:Suprachiasmatic Nucleus / Q000378:metabolism / Q000502:physiology*