title: Iminium ion cascade reaction in the total synthesis of (+)-vincadifformine.
abstract: An iminium ion triggered cascade reaction is described in the total synthesis of (+)-vincadifformine by the coupling of 3,3-substituted tetrahydropyridine and indole derivative. The strategy allows simultaneous construction of two new rings, three new sigma bonds, and two new stereogenic centers in one pot with complete stereochemical control.
authors.affiliation: Division of Organic Chemistry, National Chemical Laboratory, Pune-411008, India. gp.pandey@ncl.res.in
authors.forename: Ganesh
authors.initials: G
authors.lastname: Pandey
authors.forename: Prasanna Kumara
authors.initials: PK
authors.lastname: C
mesh_terms: D000470:Alkaloids / Q000138:chemical synthesis* / Q000737:chemistry; D007097:Imines / Q000737:chemistry*; D007477:Ions / Q000737:chemistry; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D000470:Alkaloids; D007097:Imines; D007477:Ions; C456406:vincadifformine