title: Successful treatment of cyclosporine-induced sebaceous hyperplasia with oral isotretinoin in two renal transplant recipients.
abstract: We present two cases of cyclosporine-induced sebaceous hyperplasia in renal transplant recipients, successfully treated with isotretinoin. Both patients tolerated isotretinoin well, with no alteration in graft function. These cases provide support for the safe and effective use of oral isotretinoin in the treatment of cyclosporine-induced sebaceous hyperplasia in the kidney transplant population.
authors.affiliation: Department of Medicine (Dermatology), St Vincent's Hospital, Melbourne, Victoria, Australia. alvin.chong@svhm.org.au
authors.forename: Sarah K
authors.initials: SK
authors.lastname: McDonald
authors.forename: Michelle S
authors.initials: MS
authors.lastname: Goh
authors.forename: Alvin H
authors.initials: AH
authors.lastname: Chong
mesh_terms: D000328:Adult; D016572:Cyclosporine / Q000009:adverse effects; D003879:Dermatologic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D005148:Facial Dermatoses / Q000139:chemically induced / Q000188:drug therapy* / Q000473:pathology*; D006801:Humans; D006965:Hyperplasia / Q000139:chemically induced / Q000188:drug therapy; D007166:Immunosuppressive Agents / Q000009:adverse effects; D015474:Isotretinoin / Q000008:administration & dosage / Q000627:therapeutic use*; D016030:Kidney Transplantation / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D012627:Sebaceous Glands / Q000473:pathology*
chemical_list: D003879:Dermatologic Agents; D007166:Immunosuppressive Agents; D016572:Cyclosporine; D015474:Isotretinoin