title: Hyperthyroidism presenting with hyperglycemia in an adolescent female.
abstract: A 15-year-old female presented to a pediatric emergency department with glycosuria, ketonuria, and hyperglycemia and was admitted with a presumed diagnosis of diabetes mellitus. The patient required no insulin therapy and only minor dietary modification to maintain euglycemia. Clinical examination and laboratory findings revealed a primary diagnosis of Graves' hyperthyroidism with associated impaired glucose tolerance. Here, we review the mechanisms of thyrotoxicosis resulting in impaired glucose metabolism.
authors.affiliation: Division of Endocrinology, Department of Pediatrics, University of Louisville, Louisville, KY 40202, USA. kawint01@louisville.edu
authors.forename: Kupper A
authors.initials: KA
authors.lastname: Wintergerst
authors.forename: Erica S
authors.initials: ES
authors.lastname: Rogers
authors.forename: Michael B
authors.initials: MB
authors.lastname: Foster
mesh_terms: D000293:Adolescent; D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use; D013956:Antithyroid Agents / Q000627:therapeutic use; D001786:Blood Glucose / Q000378:metabolism; D005260:Female; D006111:Graves Disease / Q000097:blood / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D006801:Humans; D006943:Hyperglycemia / Q000097:blood / Q000209:etiology*; D007457:Iodine Radioisotopes / Q000627:therapeutic use; D008713:Methimazole / Q000627:therapeutic use; D011433:Propranolol / Q000627:therapeutic use; D013971:Thyrotoxicosis / Q000097:blood / Q000150:complications / Q000175:diagnosis / Q000628:therapy; D013974:Thyroxine / Q000627:therapeutic use
chemical_list: D000319:Adrenergic beta-Antagonists; D013956:Antithyroid Agents; D001786:Blood Glucose; D007457:Iodine Radioisotopes; D008713:Methimazole; D011433:Propranolol; D013974:Thyroxine