title: A fluorescent turn-on probe for the detection of alkaline phosphatase activity in living cells.
abstract: Fluorescent probe 1, showing a high fluorescence turn-on signal ratio, enables the real-time imaging of endogenous alkaline phosphatase (ALP) activity in living cells, and the fast and quantitative analysis of enzyme activity at the single-cell level.
authors.affiliation: Department of Chemistry, Dankook University, Yongin-si, Gyeonggi-do, Korea.
authors.forename: Tae-Il
authors.initials: TI
authors.lastname: Kim
authors.forename: Hyunjin
authors.initials: H
authors.lastname: Kim
authors.forename: Yongdoo
authors.initials: Y
authors.lastname: Choi
authors.forename: Youngmi
authors.initials: Y
authors.lastname: Kim
mesh_terms: D000469:Alkaline Phosphatase / Q000378:metabolism*; D002470:Cell Survival; D005456:Fluorescent Dyes / Q000737:chemistry*; D006367:HeLa Cells; D006801:Humans; D042541:Intracellular Space / Q000201:enzymology; D057054:Molecular Imaging / Q000379:methods*; D013997:Time Factors
chemical_list: D005456:Fluorescent Dyes; D000469:Alkaline Phosphatase