title: Association between ABO blood groups and osteoporosis severity in Chinese adults aged 50 years and over.
abstract: This study investigated whether the ABO blood groups contributed to the severity of osteoporosis in 1452 community-dwelling Chinese adults aged 50-85 years. Osteoporosis severity was scored as: F(0), no osteoporosis; F(1), osteopenia; F(2), osteoporosis; and F(3), severe osteoporosis. The proportions of adults with a non-O blood group were 55.0%, 62.0%, 70.8% and 72.6% for the groups with F(0), F(1), F(2) and F(3) osteoporosis scores, respectively. Having a non-O blood group was associated with an increased severity of osteoporosis, even after adjustment for gender, age and cigarette consumption (odds ratio 1.8; 95% confidence interval 1.0, 2.9). This study demonstrated that having a non-O blood group was an independent risk factor for the progression of osteoporosis in Chinese adults with osteoporosis aged ≥ 50 years.
authors.affiliation: Department of Orthopaedics, Xiangya Hospital, Central South University, Changsha, China. bangbaolu@yahoo.com.cn
authors.forename: B-B
authors.initials: BB
authors.lastname: Lu
authors.forename: K-H
authors.initials: KH
authors.lastname: Li
mesh_terms: D000017:ABO Blood-Group System; D015502:Absorptiometry, Photon; D000368:Aged; D000369:Aged, 80 and over; D002681:China; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010024:Osteoporosis / Q000097:blood* / Q000473:pathology; D012720:Severity of Illness Index
chemical_list: D000017:ABO Blood-Group System