title: Breast enlargement with prednisone treatment.
abstract: A 17-year-old boy sought endocrine advice for an unusual gynecomastia that inexplicably recurred whenever he was treated with prednisone. This began at the age of 14, when the patient was diagnosed as having Addison's disease and was first treated with prednisone. An ensuing breast enlargement caused him to stop the medication and a regression of the gynecomastia was observed. Breast enlargement reappeared each time prednisone treatment resumed. Review of this problem led to the final diagnosis of congenital adrenal hyperplasia in a teenager who was genetically female but phenotypically male.
authors.affiliation: Endocrine and Metabolism Research Center, Shiraz University of Medical Sciences, Shiraz, Iran. pishdadg@sums.ac.ir
authors.forename: Gholam Reza
authors.initials: GR
authors.lastname: Pishdad
authors.forename: Parisa
authors.initials: P
authors.lastname: Pishdad
authors.forename: Reza
authors.initials: R
authors.lastname: Pishdad
mesh_terms: D000224:Addison Disease / Q000188:drug therapy; D000293:Adolescent; D000312:Adrenal Hyperplasia, Congenital / Q000503:physiopathology; D005260:Female; D006177:Gynecomastia / Q000139:chemically induced*; D006801:Humans; D008297:Male; D011241:Prednisone / Q000009:adverse effects* / Q000627:therapeutic use
chemical_list: D011241:Prednisone