title: Cucurbit[8]uril rotaxanes.
abstract: The synthesis of [2]rotaxanes, each comprising a viologen core threaded through a cucurbit[8]uril (Q8, Figure 1) macrocycle and stoppered by tetraphenylmethane groups, and their binding to second guests as inclusion complexes in organic and aqueous media are described. Stoppering was observed to have little effect on binding. Chemical modification of the threaded guest was used to control solubility and binding characteristics, thus demonstrating a novel approach to making artificial receptors with readily modifiable properties.
authors.affiliation: Department of Chemistry, Trinity University, 1 Trinity Place, San Antonio, Texas 78212, USA.
authors.forename: Vijayakumar
authors.initials: V
authors.lastname: Ramalingam
authors.forename: Adam R
authors.initials: AR
authors.lastname: Urbach
mesh_terms: D001952:Bridged-Ring Compounds / Q000737:chemistry*; D007093:Imidazoles / Q000737:chemistry*; D008958:Models, Molecular; D015394:Molecular Structure; D043862:Rotaxanes / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism; D047028:Macrocyclic Compounds; D000099246:Cucurbit(n)urils
chemical_list: D001952:Bridged-Ring Compounds; D007093:Imidazoles; D043862:Rotaxanes; C507198:cucurbit(8)uril; D047028:Macrocyclic Compounds; D000099246:Cucurbit(n)urils