title: Comparison of myocardial perfusion imaging using thallium-201 between a new cadmium-zinc-telluride cardiac camera and a conventional SPECT camera.
abstract: OBJECTIVE
  Cadmium zinc telluride (CZT) solid-state detectors have been recently introduced in myocardial perfusion imaging. However, they had not been yet validated with thallium-201. This study compares the clinical performances of the CZT ultrafast camera GE DNM 530c with a conventional SPECT camera (CC) using thallium-201.
  
  
  METHODS
  We prospectively studied with thallium-201 a total of 153 consecutive patients referred for myocardial perfusion imaging at exercise (3-4 mCi) then redistribution (with 1 mCi reinjection). Sequential acquisitions were performed first with a conventional dual-head tomographic Anger camera (CC) in 10 to 15 minutes and then with a CZT camera (CZT) in 5 minutes, in prone position.
  
  
  RESULTS
  In all, 9 patients were excluded: 1 for mispositioning, 3 for camera failure, 3 for delayed acquisition after exercise, 1 for nonacceptance of redistribution, 1 for motion. Acquisition was more comfortable with CZT for all patients. Global counts rate was higher with CZT than with CC (3.6±0.57 KCts/s vs. 1.14±0.16). CZT has a 5-fold increased myocardial counts rate compared with CC (448±69 Kcts in 5 minutes vs. 209±40 Kcts in 12.5±1.8 minutes). Quality of CZT images was considered as better in 40%, equal in 56%, and worse in 4% of cases; we found less artifacts with CZT; diagnostic conclusions were the same in 140 of 144 cases (97%); discordances were 2 artifacts with CC and 2 small ischemia (less than 2 segments) missed by CZT.
  
  
  CONCLUSIONS
  This new dedicated cardiac CZT camera allows with thallium-201 five minutes acquisitions with an increased image quality and a reliable diagnosis quality.
authors.affiliation: Centre Cardiologique du Nord, Saint-Denis, Paris, France. b.songy@ccncardio.com
authors.forename: Bernard
authors.initials: B
authors.lastname: Songy
authors.forename: David
authors.initials: D
authors.lastname: Lussato
authors.forename: Mohamed
authors.initials: M
authors.lastname: Guernou
authors.forename: Mathieu
authors.initials: M
authors.lastname: Queneau
authors.forename: Ricardo
authors.initials: R
authors.lastname: Geronazzo
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016477:Artifacts; D002104:Cadmium; D005260:Female; D015902:Gamma Cameras / Q000592:standards; D006801:Humans; D008297:Male; D008875:Middle Aged; D055414:Myocardial Perfusion Imaging / Q000295:instrumentation*; D013691:Tellurium; D013794:Thallium Radioisotopes; D015899:Tomography, Emission-Computed, Single-Photon / Q000295:instrumentation* / Q000592:standards; D015032:Zinc
chemical_list: C474490:CdZnTe; D013794:Thallium Radioisotopes; D002104:Cadmium; D015032:Zinc; D013691:Tellurium