title: [Persistent contact lens-associated keratitis].
abstract: A 43-year-old woman presented with a 2-month history of contact lens-associated keratitis and corneal ulceration on the left eye. Without having isolated the pathogenic agent, a calculated anti-infective and anti-inflammatory therapy had already been administered with no signs of improvement. Filamentous fungi (Acremonium sp) were found in the scraping material and the contact lens solution. A keratoplasty à chaud was necessary despite immediate initiation of pathogen-specific therapy. Early identification of the pathogen via corneal debridement and culturing are standard procedures in order to initiate a specific therapy and prevent ulceration which can threaten the visual outcome.
authors.affiliation: Augenklinik der LMU, Klinikum der Universität München, Campus Innenstadt, Mathildenstr. 8, 80336, München, Deutschland. Annemarie.Klingenstein@med.uni-muenchen.de
authors.forename: A
authors.initials: A
authors.lastname: Klingenstein
authors.forename: W J
authors.initials: WJ
authors.lastname: Mayer
authors.forename: J
authors.initials: J
authors.lastname: Rueping
authors.forename: C
authors.initials: C
authors.lastname: Miller
authors.forename: A
authors.initials: A
authors.lastname: Kampik
authors.forename: H
authors.initials: H
authors.lastname: Mino De Kaspar
mesh_terms: D002908:Chronic Disease; D003261:Contact Lenses / Q000009:adverse effects*; D003320:Corneal Ulcer / Q000175:diagnosis* / Q000209:etiology* / Q000517:prevention & control; D003646:Debridement; D005260:Female; D006801:Humans; D007634:Keratitis / Q000175:diagnosis* / Q000209:etiology* / Q000601:surgery; D008875:Middle Aged; D016896:Treatment Outcome