title: [Rapid analysis of psoralen and isopsoralen in Psoralea corylifolia by microwave-assisted extraction].
abstract: OBJECTIVE
  To establish a convenient and rapid method of microwave-assisted extraction (MAE) for the extraction of psoralen and isopsoralen in Psoralea corylifolia.
  
  
  METHODS
  The effects of various parameters on the MAE were investigated with several single-factor tests, and compared with the traditional extraction.
  
  
  RESULTS
  The optimal conditions of MAE were as follows: the extractine time was 3 min, and the ratio of solvent to material was 400 mL x g(-1) by using methanol as the solvent. Compared with soxhlet extraction, heat reflux extraction, and ultrasound-assisted extraction, MAE needed only 3 min to give the highest yield of psoralen and isopsoralen, while the other extraction methods needed several hours and gave lower yield.
  
  
  CONCLUSIONS
  The proposed method has greatly shortened extraction time and improved extraction yield, so it provides a neotype, simple and rapid measure for the separation of psoralen and isopsoralen from P. corylifolia.
authors.affiliation: School of Pharmacy, Hebei Medical University, Shijiazhuang 050017.
authors.forename: Yanfang
authors.initials: Y
authors.lastname: Lu
authors.forename: Jing
authors.initials: J
authors.lastname: An
authors.forename: Ye
authors.initials: Y
authors.lastname: Jiang
mesh_terms: D002851:Chromatography, High Pressure Liquid; D005363:Ficusin / Q000737:chemistry*; D011564:Furocoumarins / Q000737:chemistry*; D008872:Microwaves; D029907:Psoralea / Q000737:chemistry*; D015203:Reproducibility of Results
chemical_list: D011564:Furocoumarins; C011659:angelicin; D005363:Ficusin