title: Innate immune responses to Pseudomonas aeruginosa infection.
abstract: Innate immune responses play a critical role in controlling acute infections due to Pseudomonas aeruginosa in both mice and in humans. In this review we focus on innate immune recognition and clearance mechanisms that are important for controlling P. aeruginosa in the mammalian lung, with particular attention to those that influence the outcome of in vivo infection in murine models.
authors.affiliation: Department of Internal Medicine (Infectious Diseases), Yale University School of Medicine, New Haven, CT 06520-8022, USA.
authors.forename: Elise G
authors.initials: EG
authors.lastname: Lavoie
authors.forename: Tamding
authors.initials: T
authors.lastname: Wangdi
authors.forename: Barbara I
authors.initials: BI
authors.lastname: Kazmierczak
mesh_terms: D000818:Animals; D001426:Bacterial Proteins / Q000276:immunology*; D003165:Complement System Proteins / Q000276:immunology; D016207:Cytokines / Q000276:immunology; D003713:Dendritic Cells / Q000276:immunology; D006801:Humans; D007113:Immunity, Innate; D058847:Inflammasomes / Q000276:immunology; D008070:Lipopolysaccharides / Q000276:immunology / Q000378:metabolism; D008168:Lung / Q000276:immunology* / Q000382:microbiology; D008214:Lymphocytes / Q000276:immunology; D016676:Macrophages, Alveolar / Q000276:immunology; D051379:Mice; D018345:Mice, Knockout; D009504:Neutrophils / Q000276:immunology; D011014:Pneumonia / Q000276:immunology* / Q000382:microbiology; D011552:Pseudomonas Infections / Q000276:immunology* / Q000382:microbiology; D011550:Pseudomonas aeruginosa / Q000276:immunology*; D051192:Receptors, Pattern Recognition / Q000276:immunology; D015398:Signal Transduction / Q000276:immunology*
chemical_list: D001426:Bacterial Proteins; D016207:Cytokines; D058847:Inflammasomes; D008070:Lipopolysaccharides; D051192:Receptors, Pattern Recognition; D003165:Complement System Proteins