title: The battle over inhibitory synaptic plasticity in satiety brain circuits.
abstract: The synaptic basis underlying food intake is poorly understood. New research shows that an animal's satiety state dictates the polarity of long-term inhibitory synaptic plasticity in the hypothalamus, which is mediated by an activity-dependent competition between endocannabinoid and nitric oxide signaling.
authors.affiliation: Dominick P. Purpura Department of Neuroscience, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
authors.forename: Thomas J
authors.initials: TJ
authors.lastname: Younts
authors.forename: Pablo E
authors.initials: PE
authors.lastname: Castillo