title: [Interleukin network in pulmonary tuberculosis].
abstract: Pulmonary tuberculosis is an infectious disease caused by Mycobacterium tuberculosis which establishes intracellular parasitism in phagosomes of macrophages as initial infection sites. When host immune system recognizes the bacteria, anti-mycobacterial immunity is activated by various cytokines including interleukins, tumor necrosis factor-alpha and interferon-gamma. The cytokines form a network of co-operative action and mutual regulation. In this review, role of the network of interleukins and cytokines in protection against pulmonary tuberculosis will be discussed.
authors.affiliation: Molecular Microbiology Group, Department of Tropical Infectious Diseases, Tropical Biosphere Research Center, University of the Ryukyus.
authors.forename: Goro
authors.initials: G
authors.lastname: Matsuzaki
authors.forename: Masayuki
authors.initials: M
authors.lastname: Umemura
mesh_terms: D006801:Humans; D007378:Interleukins / Q000502:physiology*; D014397:Tuberculosis, Pulmonary / Q000276:immunology*
chemical_list: D007378:Interleukins