title: [Arsine: an unknown industrial chemical toxic].
abstract: Arsines family includes many compounds with various toxicities. Arsenic trihydride or arsine is the most toxic form of arsenic. Powerful haemolytic gas, it has never been used as a chemical weapon because its toxicity is not immediate and it is non persistent. However, cases of industrial poisoning with arsine are still identified in spite of a strict regulation at work. It is also identified as a potential toxic of chemical terrorism. This agent, of which the mechanism of action is still not well defined, is badly recognized because of intoxications rarity. However, fast detection means are available. Health professionals and especially those who are involved in piratox plan need to learn to recognize arsine intoxication (hematuria, oliguria, haemolytic anemia) in order to provide early, specific treatment and avoid damages.
authors.affiliation: Département contrôle analytique, pharmacie centrale des armées, Fleury-les-Aubrais cedex, France. j.plantamura@yahoo.fr
authors.forename: J
authors.initials: J
authors.lastname: Plantamura
authors.forename: F
authors.initials: F
authors.lastname: Dorandeu
authors.forename: P
authors.initials: P
authors.lastname: Burnat
authors.forename: C
authors.initials: C
authors.lastname: Renard
mesh_terms: D020261:Arsenic Poisoning / Q000175:diagnosis / Q000517:prevention & control / Q000628:therapy*; D001152:Arsenicals / Q000493:pharmacokinetics; D006801:Humans; D009784:Occupational Diseases / Q000139:chemically induced / Q000175:diagnosis / Q000628:therapy; D016273:Occupational Exposure; D014018:Tissue Distribution
chemical_list: D001152:Arsenicals; C006633:arsine