title: Pure seminoma: a review and update.
abstract: Pure seminoma is a rare pathology of the young adult, often discovered in the early stages. Its prognosis is generally excellent and many therapeutic options are available, especially in stage I tumors. High cure rates can be achieved in several ways: standard treatment with radiotherapy is challenged by surveillance and chemotherapy. Toxicity issues and the patients' preferences should be considered when management decisions are made. This paper describes firstly the management of primary seminoma and its nodal involvement and, secondly, the various therapeutic options according to stage.
authors.affiliation: Department of Radiation Oncology, Centre Hospitalier Universitaire Vaudois (CHUV), Bugnon 46, CH-1011 Lausanne, Switzerland. nboujelbene@gmail.com
authors.forename: Noureddine
authors.initials: N
authors.lastname: Boujelbene
authors.forename: Adrien
authors.initials: A
authors.lastname: Cosinschi
authors.forename: Nadia
authors.initials: N
authors.lastname: Boujelbene
authors.forename: Kaouthar
authors.initials: K
authors.lastname: Khanfir
authors.forename: Shushila
authors.initials: S
authors.lastname: Bhagwati
authors.forename: Eveleyn
authors.initials: E
authors.lastname: Herrmann
authors.forename: Rene-Olivier
authors.initials: RO
authors.lastname: Mirimanoff
authors.forename: Mahmut
authors.initials: M
authors.lastname: Ozsahin
authors.forename: Abderrahim
authors.initials: A
authors.lastname: Zouhair
mesh_terms: D000293:Adolescent; D000328:Adult; D001706:Biopsy / Q000379:methods; D002986:Clinical Trials as Topic; D003131:Combined Modality Therapy / Q000379:methods; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D008495:Medical Oncology / Q000379:methods; D009367:Neoplasm Staging; D011379:Prognosis; D011878:Radiotherapy / Q000379:methods; D012008:Recurrence; D018239:Seminoma / Q000175:diagnosis* / Q000628:therapy*; D013736:Testicular Neoplasms / Q000175:diagnosis* / Q000628:therapy*; D016896:Treatment Outcome