title: Growth of hydroxyapatite on physiologically clotted fibrin capped gold nanoparticles.
abstract: The growth of hydroxyapatite (HAp) on physiologically clotted fibrin (PCF)-gold nanoparticles is presented for the first time by employing a wet precipitation method. Fourier transform infrared (FTIR) spectroscopy confirmed the characteristic functionalities of PCF and HAp in the PCF-Au-HAp nanocomposite. Scanning electron microscopy (SEM) images have shown cuboidal nanostructures having a size in the range of 70-300 nm of HAp, whereas 2-50 nm sized particles were visualized in high-resolution transmission electron microscopy (TEM). Energy-dispersive x-ray (EDX) and x-ray diffraction (XRD) studies have confirmed the presence of HAp. These results show that gold nanoparticles with PCF acted as a matrix for the growth of HAp, and that PCF-Au-HAp nanocomposite is expected to have better osteoinductive properties.
authors.forename: T P
authors.initials: TP
authors.lastname: Sastry
authors.forename: J
authors.initials: J
authors.lastname: Sundaraseelan
authors.forename: K
authors.initials: K
authors.lastname: Swarnalatha
authors.forename: S S
authors.initials: SS
authors.lastname: Liji Sobhana
authors.forename: M
authors.initials: M
authors.lastname: Uma Makheswari
authors.forename: S
authors.initials: S
authors.lastname: Sekar
authors.forename: A B
authors.initials: AB
authors.lastname: Mandal