title: Kaposi sarcoma of the adrenal gland resembling epithelioid angiosarcoma: a case report.
abstract: Patients with human immunodeficiency virus infection are known to have increased risk of various neoplasms, including Kaposi sarcoma, which classically involves the skin and mucosal locations. The anaplastic variant of Kaposi sarcoma is rare and poorly documented in the literature. It is characterised clinically by a more aggressive behaviour and increased metastatic potential, and histologically by increased cellularity, mitotic rate, and rarely by epithelioid angiosarcoma-like morphology. We report herein a 64-year-old man with a long-standing history of human immunodeficiency virus infection who developed a right adrenal tumor with a high-grade anaplastic angiosarcoma-like morphology. Immunohistochemistry for human herpes virus-8 was strongly positive in the tumor cells. To the best of our knowledge, this is the first report of an anaplastic Kaposi sarcoma in the adrenal gland.
authors.affiliation: Anatomical Pathology JP1401, Vancouver Hospital, 855 West 12th Avenue, Vancouver, BC, V5Z 1M9, Canada.
authors.forename: Hassan
authors.initials: H
authors.lastname: Huwait
authors.forename: Adam
authors.initials: A
authors.lastname: Meneghetti
authors.forename: Torsten O
authors.initials: TO
authors.lastname: Nielsen