title: Behaviour and metabolic control in children with Type 1 diabetes mellitus on insulin pump therapy: 2-year follow-up.
abstract: OBJECTIVE
  This study investigated whether continuous subcutaneous insulin infusion is associated with sustained improvement in behaviour and metabolic control.
  
  
  METHODS
  Children with Type 1 diabetes mellitus (n = 27, 8-18 years old) who had been assessed previously prior to commencing continuous subcutaneous insulin infusion, and 6-8 weeks later, were re-evaluated 2 years after commencing insulin pump therapy. Behaviour was reassessed using the Behavioral Assessment System for Children-2nd edition (BASC-2) and current HbA(1c) levels were recorded.
  
  
  RESULTS
  Two years after commencing continuous subcutaneous insulin infusion, parent-reported internalizing and externalizing symptoms were significantly lower than pre-insulin pump therapy commencement levels. Self reports of internalizing and externalizing problems did not differ significantly across the three assessment points. There was no significant difference between pre-insulin pump therapy HbA(1c) and HbA(1c) after 2 years on continuous subcutaneous insulin infusion, despite an initial improvement 6-8 weeks after commencing the therapy.
  
  
  CONCLUSIONS
  Children with Type 1 diabetes mellitus showed sustained improvements in parent-reported behaviour, but not in self reports of behaviour or in metabolic control 2 years after commencement of continuous subcutaneous insulin infusion.
authors.affiliation: Murdoch Childrens Research Institute, Royal Children's Hspital, Victoria, Australia. sarah.knight@mcri.edu.au
authors.forename: S J
authors.initials: SJ
authors.lastname: Knight
authors.forename: E A
authors.initials: EA
authors.lastname: Northam
authors.forename: F J
authors.initials: FJ
authors.lastname: Cameron
authors.forename: G R
authors.initials: GR
authors.lastname: Ambler
mesh_terms: D000293:Adolescent; D002648:Child; D002652:Child Behavior; D003922:Diabetes Mellitus, Type 1 / Q000097:blood / Q000188:drug therapy* / Q000523:psychology; D005260:Female; D005500:Follow-Up Studies; D006442:Glycated Hemoglobin / Q000378:metabolism*; D006801:Humans; D007004:Hypoglycemic Agents / Q000008:administration & dosage*; D007328:Insulin / Q000008:administration & dosage*; D007332:Insulin Infusion Systems; D008297:Male; D057566:Self Report
chemical_list: D006442:Glycated Hemoglobin; D007004:Hypoglycemic Agents; D007328:Insulin