title: High-throughput age synchronisation of Caenorhabditis elegans.
abstract: We present a passive microfluidic strategy for sorting adult C. elegans nematodes on the basis of age and size. The separation mechanism takes advantage of phenotypic differences between 'adult' and 'juvenile' organisms and their behaviour in microfluidic architectures. In brief, the microfluidic device allows worms to sort themselves in a passive manner.
authors.affiliation: Department of Chemistry, Imperial College London, London, UK. x.casadevall-i-solvas@imperial.ac.uk
authors.forename: Xavier
authors.initials: X
authors.lastname: Casadevall i Solvas
authors.forename: Florian M
authors.initials: FM
authors.lastname: Geier
authors.forename: Armand M
authors.initials: AM
authors.lastname: Leroi
authors.forename: Jake G
authors.initials: JG
authors.lastname: Bundy
authors.forename: Joshua B
authors.initials: JB
authors.lastname: Edel
authors.forename: Andrew J
authors.initials: AJ
authors.lastname: DeMello
mesh_terms: D000375:Aging; D000818:Animals; D049628:Body Size; D017173:Caenorhabditis elegans / Q000254:growth & development / Q000302:isolation & purification* / Q000502:physiology*; D046210:Microfluidic Analytical Techniques / Q000379:methods*; D013997:Time Factors