title: MRI of chondromyxoid fibroma.
abstract: BACKGROUND
  Chondromyxoid fibroma is a rare benign primary bone tumor of cartilage. Despite a characteristic radiographic appearance, chondromyxoid fibroma with atypical radiographic findings may mimic more common tumors.
  
  
  OBJECTIVE
  To describe the MR findings of chondromyxoid fibroma.
  
  
  METHODS
  MR images of 19 histopathologically confirmed chondromyxoid fibromas were retrospectively analyzed for signal intensity, periosteal reaction, adjacent abnormal bone marrow and soft tissue signal, and patterns of contrast enhancement.
  
  
  RESULTS
  All cases of chondromyxoid fibroma showed hypointense to intermediate signal intensity and internal hyperintense foci were observed in seven (37%) cases on T1-weighted images. On T2-weighted images, all lesions were hyperintense: peripheral intermediate signal band with central hyperintense signal in 11 (58%) of 19 lesions, whereas diffusely hyperintense with heterogeneous pattern in eight (42%). Periosteal reaction was observed in 11 (58%) of 19 cases. Adjacent abnormal bone marrow or soft tissue signal was observed in 12 (63%) or 14 (74%) of 19 cases, respectively. On contrast-enhanced T1-weighted images, peripheral nodular enhancement was observed in 69% (11/16) and diffuse contrast enhancement was observed in 31% (5/16) with homogeneous (n = 3) or heterogeneous (n = 2) patterns. Among the cases with peripheral nodular enhancement, the peripheral nodular enhancing portion generally corresponded to the peripheral intermediate signal band on T2-weighted images, although the peripheral enhancement was not as wide as a band of intermediate signal intensity. On the other hand, the central non-enhancing portion generally corresponded to the central hyperintense signal intensity on T2-weighted images.
  
  
  CONCLUSIONS
  The helpful features of chondromyxoid fibroma are the peripheral intermediate signal band and central hyperintense signal on T2-weighted images, generally corresponding to the peripheral nodular enhancement and central non-enhancing portion on contrast-enhanced T1-weighted images, respectively.
authors.affiliation: Department of Radiology, Seoul St Mary's Hospital, School of Medicine, The Catholic University of Korea, Korea.
authors.forename: Hyun-Soo
authors.initials: HS
authors.lastname: Kim
authors.forename: Won-Hee
authors.initials: WH
authors.lastname: Jee
authors.forename: Kyung-Nam
authors.initials: KN
authors.lastname: Ryu
authors.forename: Kil-Ho
authors.initials: KH
authors.lastname: Cho
authors.forename: Jin-Suck
authors.initials: JS
authors.lastname: Suh
authors.forename: Jae-Hyun
authors.initials: JH
authors.lastname: Cho
authors.forename: Yun-Sun
authors.initials: YS
authors.lastname: Choi
authors.forename: Sung Moon
authors.initials: SM
authors.lastname: Lee
authors.forename: Jong-Min
authors.initials: JM
authors.lastname: Lee
authors.forename: Mi Sook
authors.initials: MS
authors.lastname: Sung
authors.forename: Jee Young
authors.initials: JY
authors.lastname: Kim
authors.forename: Eun Sun
authors.initials: ES
authors.lastname: Jung
authors.forename: Yang-Guk
authors.initials: YG
authors.lastname: Chung
authors.forename: In-Young
authors.initials: IY
authors.lastname: Ok
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001859:Bone Neoplasms / Q000473:pathology*; D002648:Child; D002812:Chondroma / Q000473:pathology*; D003287:Contrast Media; D005260:Female; D005350:Fibroma / Q000473:pathology*; D019786:Gadolinium DTPA; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies
chemical_list: D003287:Contrast Media; D019786:Gadolinium DTPA