title: Ethnic differences in prostate cancer.
abstract: BACKGROUND
  It is recognised that the risk of prostate cancer is higher in black men than in white men worldwide. Recent studies suggest that a number of genetic mutations in black men predispose them to this disease; hence, race as well as environmental factors such as diet and migration are thought to be the determining factors.
  
  
  METHODS
  This review compares data from the United States (US), which suggest that African-American men have a 60% higher risk for developing prostate cancer with poorer prognosis in comparison with their white counterparts, with similar studies carried out in the United Kingdom (UK) and also in African and Caribbean countries.
  
  
  CONCLUSIONS
  Studies from the United States and the United Kingdom came to significantly different conclusions, and this has implications for policy development, awareness raising among black men in each country and clinical practice.
authors.affiliation: Department of Urology, St Bartholomew's hospital, Barts and The London NHS Trust, West Smithfield, London EC1A 7BE, UK. K_Pejman@hotmail.com
authors.forename: P
authors.initials: P
authors.lastname: Kheirandish
authors.forename: F
authors.initials: F
authors.lastname: Chinegwundoh
mesh_terms: D000349:Africa / Q000208:ethnology; D001741:Black or African American / Q000706:statistics & numerical data*; D000368:Aged; D000369:Aged, 80 and over; D044383:Black People / Q000706:statistics & numerical data*; D017691:Caribbean Region / Q000208:ethnology; D017281:Cost of Illness; D004041:Dietary Fats / Q000008:administration & dosage / Q000009:adverse effects; D005247:Feeding Behavior; D020022:Genetic Predisposition to Disease; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D011471:Prostatic Neoplasms / Q000097:blood / Q000208:ethnology* / Q000209:etiology* / Q000235:genetics / Q000401:mortality; D015203:Reproducibility of Results; D012107:Research Design; D012307:Risk Factors; D013739:Testosterone / Q000097:blood; D006113:United Kingdom / Q000453:epidemiology; D014481:United States / Q000453:epidemiology; D044465:White People / Q000706:statistics & numerical data
chemical_list: D004041:Dietary Fats; D013739:Testosterone