title: Prevalence of aac(6')-Ib-cr plasmid-mediated and chromosome-encoded fluoroquinolone resistance in Enterobacteriaceae in Italy.
abstract: The spread of aac(6')-Ib-cr plasmid-mediated quinolone resistance determinants was evaluated in 197 enterobacterial isolates recovered in an Italian teaching hospital. The aac(6')-Ib-cr gene was found exclusively in Escherichia coli strains. The gene was located on a plasmid which presented additional ESBL genes. Most of the clinical strains were clonally related and displayed three point mutations at the topoisomerase level which conferred high resistance to fluoroquinolones.
authors.affiliation: Department of Histology, Microbiology and Medical Biotechnologies, University of Padua, via Gabelli 63, 35121 Padua, Italy. sara.richter@unipd.it.
authors.forename: Ilaria
authors.initials: I
authors.lastname: Frasson
authors.forename: Antonietta
authors.initials: A
authors.lastname: Cavallaro
authors.forename: Cristina
authors.initials: C
authors.lastname: Bergo
authors.forename: Sara N
authors.initials: SN
authors.lastname: Richter
authors.forename: Giorgio
authors.initials: G
authors.lastname: Palù