title: Antioxidant and urease inhibitory C-glycosylflavonoids from Celtis africana.
abstract: Two new C-glycosylflavonoids celtisides A (1) and B (2) have been isolated from n-butanol-soluble fraction of Celtis africana, along with five known C-glycosylflavonoids vitexin (3), orientin (4), isoswertiajaponin (5), isoswertisin (6), and 2″-O-rhamnosyl vitexin (7) reported for the first time from this species. Their structures were assigned from 1D and 2D NMR spectra. These compounds were investigated for biological activities and showed significant antioxidant and urease inhibitory activities.
authors.affiliation: Department of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh 2457, Riyadh 11451, Saudi Arabia. shakhan@ksu.edu.sa
authors.forename: Shagufta
authors.initials: S
authors.lastname: Perveen
authors.forename: Azza Muhammed
authors.initials: AM
authors.lastname: El-Shafae
authors.forename: Areej
authors.initials: A
authors.lastname: Al-Taweel
authors.forename: Ghada Ahmed
authors.initials: GA
authors.lastname: Fawzy
authors.forename: Abdul
authors.initials: A
authors.lastname: Malik
authors.forename: Nighat
authors.initials: N
authors.lastname: Afza
authors.forename: Mehreen
authors.initials: M
authors.lastname: Latif
authors.forename: Lubna
authors.initials: L
authors.lastname: Iqbal
mesh_terms: D000975:Antioxidants / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D047310:Apigenin / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D005419:Flavonoids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D005960:Glucosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D006801:Humans; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D012529:Saudi Arabia; D034401:Ulmaceae / Q000737:chemistry*; D014510:Urease / Q000037:antagonists & inhibitors*
chemical_list: D000975:Antioxidants; D005419:Flavonoids; D005960:Glucosides; D006027:Glycosides; C561906:celtiside A; C561907:celtiside B; D047310:Apigenin; C032731:vitexin; D014510:Urease; C065886:orientin