title: Clinical characteristics of small bowel tumors diagnosed by double-balloon endoscopy: KASID multi-center study.
abstract: BACKGROUND
  Small bowel tumors are relatively rare, and their confirmative diagnosis before surgery is not easy.
  
  
  OBJECTIVE
  This study was performed to investigate the clinical characteristics of patients with small bowel tumors who received double-balloon enteroscopy (DBE). Secondary end points were to evaluate the usefulness and safety of DBE for the diagnosis of patients with suspected SB tumors derived from other previous procedures.
  
  
  METHODS
  We retrospectively analyzed consecutive DBE examinations to explore the small intestine in eight university hospitals over a 5-year period.
  
  
  RESULTS
  A total of 877 DBE examinations (per oral 487, per anal 390) were performed in 645 patients (405 males, mean age 48.2 years). Small bowel tumors were diagnosed in 112 patients (17.4%), of which 38 patients had benign polyps, 29 had gastrointestinal stromal tumors/leiomyomata, 18 had lymphomas, 14 had adenocarcinomas, five had metastatic or invasive cancers, five had lipomas, and three patients had cystic tumors. The main reasons for DBE among patients with small bowel tumors were obscure gastrointestinal bleeding (OGIB, 40.2%) followed by abnormal imaging study (25.2%). The concordance rate of diagnoses based on DBE with diagnoses based on small bowel follow-through, CT, and capsule endoscopy among patients with small bowel tumors was 68.9% (42/61), 75.3% (70/93), and 78.3% (18/23), respectively. Therapeutic plans were changed due to the DBE results in 64.2% of patients with small bowel tumors.
  
  
  CONCLUSIONS
  Approximately one-sixth of patients who received DBE had small bowel tumors, and the most common reason for DBE among patients with small bowel tumors was OGIB. DBE is a useful method for the confirmative diagnosis of small bowel tumors and has a good clinical impact on therapeutic plans and short-term clinical results.
authors.affiliation: Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea.
authors.forename: Bo-In
authors.initials: BI
authors.lastname: Lee
authors.forename: Hwang
authors.initials: H
authors.lastname: Choi
authors.forename: Kyu-Yong
authors.initials: KY
authors.lastname: Choi
authors.forename: Jeong-Sik
authors.initials: JS
authors.lastname: Byeon
authors.forename: Hyun-Joo
authors.initials: HJ
authors.lastname: Jang
authors.forename: Chang-Soo
authors.initials: CS
authors.lastname: Eun
authors.forename: Jae Hee
authors.initials: JH
authors.lastname: Cheon
authors.forename: Sung Jae
authors.initials: SJ
authors.lastname: Shin
authors.forename: Jin-Oh
authors.initials: JO
authors.lastname: Kim
authors.forename: Moon-Sung
authors.initials: MS
authors.lastname: Lee
authors.forename: Jai-Hyun
authors.initials: JH
authors.lastname: Choi
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis / Q000473:pathology*; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001706:Biopsy; D002404:Catheterization; D002648:Child; D016099:Endoscopy, Gastrointestinal / Q000009:adverse effects / Q000295:instrumentation / Q000379:methods*; D005260:Female; D046152:Gastrointestinal Stromal Tumors / Q000175:diagnosis / Q000473:pathology*; D006801:Humans; D007082:Ileum / Q000473:pathology; D007414:Intestinal Neoplasms / Q000175:diagnosis / Q000473:pathology*; D007583:Jejunum / Q000473:pathology; D008223:Lymphoma / Q000175:diagnosis / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D055815:Young Adult