title: Synthesis, characterization and biological activity of some new VO(IV), Co(II), Ni(II), Cu(II) and Zn(II) complexes of chromone based NNO Schiff base derived from 2-aminothiazole.
abstract: Coordination compounds of VO(IV), Co(II), Ni(II), Cu(II) and Zn(II) with the Schiff base obtained through the condensation of 2-aminothiazole with 3-formyl chromone were synthesized. The compounds were characterized by (1)H, (13)C NMR, UV-Vis, IR, Mass, EPR, molar conductance and magnetic susceptibility measurements. The Cu(II) complex possesses tetrahedrally distorted square planar geometry whereas Co(II), Ni(II), and Zn(II) show distorted tetrahedral geometry. The VO(IV) complex shows square pyramidal geometry. The cyclic voltammogram of Cu (II) complex showed a well defined redox couple Cu(II)/Cu(I) with quasireversible nature. The antimicrobial activity against the species Pseudomonas aeruginosa, Escherichia coli, Staphylococcus aureus, Bacillus subtilis, Candida albigans and Aspergillus niger was screened and compared to the activity of the ligand. Emission spectrum was recorded for the ligand and the metal(II) complexes. The second harmonic generation (SHG) efficiency was measured and found to have one fourth of the activity of urea. The SEM image of the copper(II) complex implies that the size of the particles is 2 μm.
authors.affiliation: Department of Chemistry, Jayaraj Annapackiam College for Women, Periyakulam 625601, India.
authors.forename: M
authors.initials: M
authors.lastname: Kalanithi
authors.forename: D
authors.initials: D
authors.lastname: Kodimunthiri
authors.forename: M
authors.initials: M
authors.lastname: Rajarajan
authors.forename: P
authors.initials: P
authors.lastname: Tharmaraj
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001234:Aspergillus niger / Q000378:metabolism; D001412:Bacillus subtilis / Q000378:metabolism; D002176:Candida albicans / Q000378:metabolism; D003300:Copper / Q000737:chemistry*; D004578:Electron Spin Resonance Spectroscopy / Q000379:methods; D004926:Escherichia coli / Q000378:metabolism; D008024:Ligands; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D008826:Microbial Sensitivity Tests / Q000379:methods; D008855:Microscopy, Electron, Scanning / Q000379:methods; D009532:Nickel / Q000737:chemistry*; D010087:Oxides / Q000737:chemistry*; D011550:Pseudomonas aeruginosa / Q000378:metabolism; D012545:Schiff Bases / Q000737:chemistry*; D013055:Spectrophotometry, Infrared / Q000379:methods; D013056:Spectrophotometry, Ultraviolet / Q000379:methods; D013211:Staphylococcus aureus / Q000378:metabolism; D013844:Thiazoles / Q000737:chemistry*; D014639:Vanadium / Q000737:chemistry*; D015032:Zinc / Q000737:chemistry*
chemical_list: D000900:Anti-Bacterial Agents; D008024:Ligands; D010087:Oxides; D012545:Schiff Bases; D013844:Thiazoles; D014639:Vanadium; C004483:2-aminothiazole; D003300:Copper; D009532:Nickel; D015032:Zinc