title: Chemical composition and in vitro antibacterial activity of the essential oil of Phthirusa adunca from Venezuelan Andes.
abstract: In this paper, preliminary studies on the chemical characterization of Phthirusa adunca Meyer essential oil, obtained by hydrodistillation, is presented. The separation of the components was performed by GC-MS. Twenty-three compounds (94.5% of the sample) were identified of which the three major ones (76% of the sample) were beta-phellandrene (38.1%), germacrene D (26.8%) and beta-pinene (11.5%). The essential oil showed a broad spectrum of activity against Salmonella Typhi CDC 57 (100 microg/mL), Staphylococcus aureus ATCC 25923 (200 microg/mL), Enterococcus faecalis ATCC 29212 (250 microg/mL), Escherichia coli ATCC 25922 y Klebsiella pneumoniae ATCC 23357 (500 microg/mL). This is the first report on the composition and activity of the essential oil of this species.
authors.affiliation: Department of Pharmacognosy and Organic Medicaments, Facultad de Farmacia y Bioanálisis, University of Los Andes, Mérida, Venezuela 5101. flormv@ula.ve
authors.forename: Flor D
authors.initials: FD
authors.lastname: Mora
authors.forename: Nurby
authors.initials: N
authors.lastname: Ríos
authors.forename: Luis B
authors.initials: LB
authors.lastname: Rojas
authors.forename: Tulia
authors.initials: T
authors.lastname: Díaz
authors.forename: Judith
authors.initials: J
authors.lastname: Velasco
authors.forename: Juan A
authors.initials: JA
authors.lastname: Carmona
authors.forename: Bladimiro
authors.initials: B
authors.lastname: Silva
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects; D008401:Gas Chromatography-Mass Spectrometry; D028183:Loranthaceae / Q000737:chemistry*; D008826:Microbial Sensitivity Tests; D039821:Monoterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D009822:Oils, Volatile / Q000737:chemistry* / Q000494:pharmacology*; D035261:Plant Components, Aerial / Q000737:chemistry; D010938:Plant Oils / Q000737:chemistry* / Q000494:pharmacology; D014687:Venezuela
chemical_list: D000900:Anti-Bacterial Agents; D039821:Monoterpenes; D009822:Oils, Volatile; D010938:Plant Oils