title: [Natural course of preneoplastic bronchial lesions].
abstract: Advances in endoscopic technology have improved the detection of precancerous bronchial lesions associated with the occurence of proximal squamous cell lung cancer (SCC) in high-risk individuals for broncho-pulmonary neoplasm. The debates and controversies regarding the control and treatment of intraepitelial bronchial lesions is due to the fact that the regression rate of all preneoplastic bronchial lesions is 54%. But the progression to carcinoma in situ or to cancer is significantly higher for severe dysplasia, than for preneoplastic lesions showing lower-grade dysplasia, such as squamous metaplasia and mild or moderate dysplasia. The progression rate to carcinoma in situ or cancer with squamous cells varies between 19% and 46% for patients with severe dysplasia. The diagnosis and resection of pulmonary cancer in incipient stages increases spectacularly the survival rates of the resected patients, by comparison to the non-operated patients.
authors.affiliation: Institutul de Pneumoftiziologie "Marius Nasta" Bucureşti, Facultatea de Medicină şi Farmnacie - Universitatea Oradea - Catedra de Pneumoftiziologie. r_ulmeanu@yahoo.com
authors.forename: Ruxandra
authors.initials: R
authors.lastname: Ulmeanu
authors.forename: Ruxandra
authors.initials: R
authors.lastname: Râjnoveanu
authors.forename: Eugenia
authors.initials: E
authors.lastname: Halic
authors.forename: Oana
authors.initials: O
authors.lastname: Deleanu
authors.forename: Florin
authors.initials: F
authors.lastname: Mihălţan
mesh_terms: D001980:Bronchi / Q000473:pathology*; D001984:Bronchial Neoplasms / Q000175:diagnosis / Q000209:etiology*; D001999:Bronchoscopy; D002278:Carcinoma in Situ / Q000175:diagnosis / Q000209:etiology; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis / Q000209:etiology; D002471:Cell Transformation, Neoplastic; D006801:Humans; D009361:Neoplasm Invasiveness; D011230:Precancerous Conditions / Q000473:pathology*; D012307:Risk Factors