title: Interkinetic nuclear migration: reciprocal activities of dynein and kinesin.
abstract: A hallmark of neurogenesis in vertebrate is the apical-basal fluctuation of radial glia nuclei. Such a phenomenon, called INM, has been known for decades and is closely associated with mitosis but still puzzles scientists. An impressive step in the molecular understanding of INM has recently been achieved by Tsai and coworkers. Using RNA interference associated with time-lapse imaging, these authors demonstrated a dual motor system that can push/pull the nuclei accordingly with the cell cycle stages.
authors.affiliation: Joint Master in Neuroscience; University of Strasbourg-France; Strasbourg, France.
authors.forename: Sofya
authors.initials: S
authors.lastname: Kulikova
authors.forename: Marios
authors.initials: M
authors.lastname: Abatis
authors.forename: Celine
authors.initials: C
authors.lastname: Heng
authors.forename: Vincent
authors.initials: V
authors.lastname: Lelievre