title: Parent-reported ISAAC written questionnaire may underestimate the prevalence of asthma in children aged 10-12 years.
abstract: OBJECTIVE
  The aim of the present study was to compare the validity of the International Study of Asthma and Allergies in Childhood (ISAAC) written (WQ) and audiovisual questionnaires (AVQ 3.0) in two age-groups (10-12 and 13-15 years, respectively).
  
  
  METHODS
  The 13-15 year olds performed the self-completed the WQ and AVQ on the same day. The 10-12 year olds performed the self-completed the AVQ and the parent-completed WQ was completed by their parents. The methacholine challenge test was conducted in 10-12 year olds from one elementary school.
  
  
  RESULTS
  In 10-12 year olds, the AVQ detected a generally higher prevalence of asthma symptoms than WQ. In 13-15 year olds, this was reversed. In 10-12 year olds, poor agreement was found between the parent-completed WQ and the self-reported AVQ. In 13-15 year olds, moderate agreement was found between the self-reported WQ and AVQ. Low sensitivity was found, in predicting bronchial hyper-responsiveness (BHR) for all questions of both WQ and AVQ in 10-12 year olds. However, the AVQ had slightly higher sensitivity than WQ, with the exception of wheeze ever, although it was not statistically significant.
  
  
  CONCLUSIONS
  The ISAAC AVQ may be another effective instrument for assessing the prevalence of asthma symptoms in children aged 10-12 years, whereas the parent-reported-WQ may underestimate the prevalence of asthma symptoms in this age-group.
authors.affiliation: Department of Epidemiology and Biostatistics, Graduate School of Public Health, Seoul National University, Seoul, Korea.
authors.forename: Myoung Hee
authors.initials: MH
authors.lastname: Kim
authors.forename: Ji-Won
authors.initials: JW
authors.lastname: Kwon
authors.forename: Hyo Bin
authors.initials: HB
authors.lastname: Kim
authors.forename: Younghwa
authors.initials: Y
authors.lastname: Song
authors.forename: Jinho
authors.initials: J
authors.lastname: Yu
authors.forename: Woo-Kyung
authors.initials: WK
authors.lastname: Kim
authors.forename: Byeong-Ju
authors.initials: BJ
authors.lastname: Kim
authors.forename: So Yeon
authors.initials: SY
authors.lastname: Lee
authors.forename: Kyoung-Won
authors.initials: KW
authors.lastname: Kim
authors.forename: Hye-Mi
authors.initials: HM
authors.lastname: Ji
authors.forename: Kyu-Earn
authors.initials: KE
authors.lastname: Kim
authors.forename: Yee-Jin
authors.initials: YJ
authors.lastname: Shin
authors.forename: Ho
authors.initials: H
authors.lastname: Kim
authors.forename: Soo-Jong
authors.initials: SJ
authors.lastname: Hong
mesh_terms: D000293:Adolescent; D001249:Asthma / Q000175:diagnosis* / Q000453:epidemiology; D016085:Bronchoconstrictor Agents; D002648:Child; D006801:Humans; D016210:Methacholine Chloride; D010290:Parents; D011237:Predictive Value of Tests; D015995:Prevalence; D015203:Reproducibility of Results; D011795:Surveys and Questionnaires / Q000592:standards*
chemical_list: D016085:Bronchoconstrictor Agents; D016210:Methacholine Chloride