title: Chemical composition and antibacterial activity of the essential oil of Lantana camara var. moritziana.
abstract: The essential oil obtained from the leaves of Lantana camara var. moritziana (Otto & Dietr.) López-Palacios collected at Rubio, Táchira State, Venezuela, was obtained by hydrodistillation in a Clevenger trap (0.1% yield). The oil was analyzed by gas chromatography-mass spectrometry (GC/MS) on HP GC-MS System, model 5973, identifying 33 compounds (97.1%) of which the major components were germacrene D (31.0%), followed by beta-caryophyllene (14.8%), a-phellandrene (6.7%), limonene (5.7%) and 1,8-cineole (5.2%). Evaluation of the antibacterial activity by agar diffusion method with discs against international reference bacteria (Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, Klebsiella pneumoniae, Salmonella Typhi, Pseudomonas aeruginosa) showed growing inhibition of E. faecalis and S. aureus at MIC of 350 mg/mL and 400 mg/mL, respectively.
authors.affiliation: Departamento de Farmacognosia y Medicamentos Orgánicos, Facultad de Farmacia y Bioanálisis, Universidad de Los Andes, Mérida, Venezuela 5101. nurbyrios@ula.ve
authors.forename: Nurby Rios
authors.initials: NR
authors.lastname: Tesch
authors.forename: Flor
authors.initials: F
authors.lastname: Mora
authors.forename: Luis
authors.initials: L
authors.lastname: Rojas
authors.forename: Tulia
authors.initials: T
authors.lastname: Díaz
authors.forename: Judith
authors.initials: J
authors.lastname: Velasco
authors.forename: Carlos
authors.initials: C
authors.lastname: Yánez
authors.forename: Nahile
authors.initials: N
authors.lastname: Rios
authors.forename: Juan
authors.initials: J
authors.lastname: Carmona
authors.forename: Sara
authors.initials: S
authors.lastname: Pasquale
mesh_terms: D001419:Bacteria / Q000187:drug effects*; D008401:Gas Chromatography-Mass Spectrometry; D032410:Lantana / Q000737:chemistry*; D008826:Microbial Sensitivity Tests; D009822:Oils, Volatile / Q000737:chemistry* / Q000494:pharmacology*; D018515:Plant Leaves / Q000737:chemistry; D010938:Plant Oils / Q000737:chemistry* / Q000494:pharmacology*; D013729:Terpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D014687:Venezuela
chemical_list: D009822:Oils, Volatile; D010938:Plant Oils; D013729:Terpenes