title: Measurements using 7.0 T post-mortem magnetic resonance imaging of the scalar dimensions of the fetal brain between 12 and 20 weeks gestational age.
abstract: In this study, scalar values for the fetal brain from 12 to 20 weeks gestational age were obtained. Fifty-two fetal specimens of 12-20 weeks gestational age with an anatomically normal and developmentally appropriate central nervous system (CNS) were scanned using a 7.0 T magnetic resonance imaging (MRI) scanner. The linear biometric measurements of the brain were then determined. All the measurements (except for the interhemispheric distance) were found to increase linearly with gestational age, although each increased at a different growth rates. The 95% confidence interval for each value was obtained. These data may be considered to be a valuable reference for the assessment of normal fetal brain development in clinical settings and as a supplement to post-mortem MRI or anatomical investigations.
authors.affiliation: Research Center for Sectional and Imaging Anatomy, Shandong University School of Medicine, 250012 Jinan, Shandong, China.
authors.forename: Xiangtao
authors.initials: X
authors.lastname: Lin
authors.forename: Zhonghe
authors.initials: Z
authors.lastname: Zhang
authors.forename: Gaojun
authors.initials: G
authors.lastname: Teng
authors.forename: Haiwei
authors.initials: H
authors.lastname: Meng
authors.forename: Taifei
authors.initials: T
authors.lastname: Yu
authors.forename: Zhongyu
authors.initials: Z
authors.lastname: Hou
authors.forename: Fang
authors.initials: F
authors.lastname: Fang
authors.forename: Fengchao
authors.initials: F
authors.lastname: Zang
authors.forename: Shuwei
authors.initials: S
authors.lastname: Liu
mesh_terms: D000818:Animals; D001344:Autopsy; D001921:Brain / Q000033:anatomy & histology* / Q000196:embryology*; D005260:Female; D005333:Fetus / Q000033:anatomy & histology* / Q000196:embryology*; D005865:Gestational Age; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000295:instrumentation / Q000379:methods* / Q000592:standards; D011247:Pregnancy