title: Partial recovery from amnesia following bilateral surgical fornix transection is correlated with cortical plasticity.
abstract: We report a case of an interventricular ependymoma which was surgically removed but also required bilateral transection of the fornices resulting in memory impairment which gradually improved. Functional MR images using a memory paradigm showed that recovery correlated with cortical plasticity involving activation of the orbitofrontal cortex and the middle temporal gyrus.
authors.affiliation: Department of Neurosurgery, Queen's Medical Centre, Nottingham, UK. nm1@doctors.org.uk
authors.forename: N K
authors.initials: NK
authors.lastname: Mazarakis
authors.forename: F
authors.initials: F
authors.lastname: Summers
authors.forename: A D
authors.initials: AD
authors.lastname: Murray
authors.forename: G D
authors.initials: GD
authors.lastname: Waiter
authors.forename: I P
authors.initials: IP
authors.lastname: Fouyas
mesh_terms: D000328:Adult; D000647:Amnesia / Q000209:etiology* / Q000503:physiopathology; D002551:Cerebral Ventricle Neoplasms / Q000000981:diagnostic imaging / Q000601:surgery*; D004806:Ependymoma / Q000000981:diagnostic imaging / Q000601:surgery*; D020712:Fornix, Brain / Q000293:injuries; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009473:Neuronal Plasticity; D009483:Neuropsychological Tests; D011183:Postoperative Complications; D017397:Prefrontal Cortex / Q000502:physiology; D011859:Radiography; D020127:Recovery of Function; D016896:Treatment Outcome