title: Tissue remodeling: making way for cellular invaders.
abstract: Cellular invasion through protein matrices is a critical process during epithelial-mesenchymal transitions. A recent study of Caenorhabditis elegans vulval development reports a novel invasive mechanism in which cells coordinate spatially restricted degradation and sliding of a basement membrane during cellular ingression and tissue formation.
authors.affiliation: Department of Zoology, University of Wisconsin, Madison, WI 53706, USA.
authors.forename: Mark
authors.initials: M
authors.lastname: Schramp
authors.forename: Jeff
authors.initials: J
authors.lastname: Hardin
mesh_terms: D000818:Animals; D017173:Caenorhabditis elegans / Q000502:physiology*; D058750:Epithelial-Mesenchymal Transition