title: 2-{1-[2,8-Bis(trifluoro-meth-yl)quinolin-4-yl]-3,5,6,7,8,8a-hexa-hydro-1H-1,3-oxazolo[3,4-a]pyridin-3-yl}phenol.
abstract: In the title mefloquine-oxazolidine derivative, C(24)H(20)F(6)N(2)O(2), the oxazoline ring adopts an envelope conformation (the flap atom is N) and the piperidine ring has a chair conformation. The oxazoline and benzene residues lie away from the C(6) ring of the quinoline group and, to a first approximation, to one side of the plane through the ten atoms (r.m.s. deviation = 0.025 Å). An intra-molecular O-H⋯N(piperidine) hydrogen bond is present. The crystal packing features C-H⋯O, C-H⋯F and C-H⋯π(hy-droxy-benzene) inter-actions.
authors.forename: Raoni S B
authors.initials: RS
authors.lastname: Gonçalves
authors.forename: Carlos R
authors.initials: CR
authors.lastname: Kaiser
authors.forename: Marcus V N
authors.initials: MV
authors.lastname: de Souza
authors.forename: James L
authors.initials: JL
authors.lastname: Wardell
authors.forename: Solange M S V
authors.initials: SM
authors.lastname: Wardell
authors.forename: Edward R T
authors.initials: ER
authors.lastname: Tiekink