title: Acellular dermal matrix slings in tissue expander breast reconstruction: are there substantial benefits?
abstract: Acellular dermal matrix (ADM) slings in breast reconstruction are increasingly used but are not yet validated. This study compares immediate, expander-based breast reconstruction with and without the use of inferolateral ADM slings. There were 63 patients (106 breasts) in the ADM group and 42 patients (68 breasts) in the control group. Initial intraoperative fill volumes were significantly greater in the ADM group, median 69% full (250 mL) versus 50% full (180 mL; P < 0.001). However, the number of days to complete expansion between the 2 groups was similar. One less office visit was required to complete the fills in the ADM group (P < 0.01). Drains were removed 3 days later in the ADM group (P < 0.01). Overall complication rate was greater in the ADM group (18.9% vs. 7.4%, P < 0.05), with a slightly higher percentage of expanders requiring removal due to infection in the ADM group (5.7% vs. 4.4%, P = NS). This study suggests inferolateral ADM slings in expander-based breast reconstruction allow for significantly increased initial fill volumes and may offer an aesthetic advantage; however, its use is costly and increases complications.
authors.affiliation: Division of Plastic Surgery, Mayo Clinic, Jacksonville, FL, USA.
authors.forename: George N
authors.initials: GN
authors.lastname: Collis
authors.forename: Sarvam P
authors.initials: SP
authors.lastname: TerKonda
authors.forename: James C
authors.initials: JC
authors.lastname: Waldorf
authors.forename: Galen
authors.initials: G
authors.lastname: Perdikis
mesh_terms: D001672:Biocompatible Materials / Q000008:administration & dosage*; D019928:Breast Implantation; D001943:Breast Neoplasms / Q000601:surgery; D003094:Collagen / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D016462:Mammaplasty / Q000295:instrumentation* / Q000379:methods; D008408:Mastectomy; D008875:Middle Aged; D011183:Postoperative Complications / Q000453:epidemiology; D012189:Retrospective Studies; D015625:Tissue Expansion Devices; D016896:Treatment Outcome
chemical_list: C440568:Alloderm; D001672:Biocompatible Materials; D003094:Collagen