title: A new acyclic thiophene sesterterpene from the Sikao Bay sponge, Xestospongia sp.
abstract: Bioactivity-guided fractionation of the ethyl acetate extract of a marine sponge, Xestospongia sp., led to the isolation of a new thiophene-S-oxide acyclic sesterterpene (1). The chemical structure was extensively analyzed using NMR and mass spectral data. Compound 1 showed weak cytotoxicity against Vero cells.
authors.affiliation: Department of Marine Science, Faculty of Sciences and Fishery Technology, Rajamangala University of Technology Srivijaya, Trang Campus, Sikao, Trang 92150, Thailand. agelas2004@gmail.com
authors.forename: Patchara
authors.initials: P
authors.lastname: Pedpradab
authors.forename: Khanit
authors.initials: K
authors.lastname: Suwanborirux
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D002522:Chlorocebus aethiops; D004354:Drug Screening Assays, Antitumor; D008386:Marine Biology; D015394:Molecular Structure; D054830:Sesterterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D013876:Thiophenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D014709:Vero Cells; D047131:Xestospongia / Q000737:chemistry*
chemical_list: C561690:3-(4,8,12,16-tetramethyl-heptadeca-3,7,11,15-tetraenyl)thiophene-1-oxide; D000970:Antineoplastic Agents; D054830:Sesterterpenes; D013876:Thiophenes