title: Hypothalamic/pituitary morbidity in skull base pathology.
abstract: In this article the epidemiology, pathophysiology, clinical presentation, investigation, management, and prognosis of hypopituitarism and hypothalamic dysfunction, arising from skull base pathologies and treatment of these conditions, are reviewed and discussed. The clinical question: "What is the consequence of pituitary hypofunction in young patients (ie, craniopharyngioma)?" is answered based on information provided in the review.
authors.affiliation: Department of Diabetes and Endocrinology, Princess Alexandra Hospital, 199 Ipswich Road, Woolloongabba, Brisbane, Queensland, Australia 4102.
authors.forename: Paul
authors.initials: P
authors.lastname: Lee
authors.forename: Ken K Y
authors.initials: KK
authors.lastname: Ho
authors.forename: Jerry R
authors.initials: JR
authors.lastname: Greenfield
mesh_terms: D000367:Age Factors; D003397:Craniopharyngioma / Q000150:complications; D006801:Humans; D007018:Hypopituitarism / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology / Q000378:metabolism; D007027:Hypothalamic Diseases / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology / Q000378:metabolism; D007030:Hypothalamo-Hypophyseal System / Q000378:metabolism / Q000473:pathology / Q000503:physiopathology; D007031:Hypothalamus / Q000378:metabolism / Q000473:pathology; D053208:Kaplan-Meier Estimate; D010902:Pituitary Gland / Q000378:metabolism / Q000473:pathology; D010907:Pituitary Hormones / Q000172:deficiency*; D019291:Skull Base / Q000473:pathology / Q000503:physiopathology; D013997:Time Factors
chemical_list: D010907:Pituitary Hormones