title: The effect of Quercus castaneifolia extract on pathogenic enteric bacteria.
abstract: The family of Enterobacteriaceae is a major group of gram negative bacteria, some of these microorganisms are pathogen and could cause disease mainly gastroenteritis. Recently, due to drug resistant nature of these bacteria specially in developing countries treatment of the patient considered as important investigate. Quercus castaneifolia is a native plant of Yasuj province in Iran, which the people who living in this area consume the fruit of this plant for treatment of enteric disease. Hence, the present study was conducted to evaluate the effect of fruit of Q. castaneifolia extract on pathogenic enteric bacteria viz., E. coli, Salmonella typhimurium, Shigella dysenteriae and Yersinia enterocolitica. Antimicrobial susceptibility and minimal inhibitory concentration (MIC) of the extracts were assessed by gel diffusion method and modification of E-test respectively. All the experiments were performed in triplicate and the statistical analysis was carried out on the results. The results obtained from this study indicated that alcoholic extract was shown antimicrobial effect on the microorganisms tested. In addition, S. dysentriae was more sensitive with zone of inhibition 18 mm and MIC value was 2.5 × 10(-4) whereas, E. coli was less sensitive with zone of inhibition 12 mm and MIC value 1 × 10(-2). Salmonella typhimurium and Yersinia enterocolitica showed relatively intermediate susceptibility to the extract with zone of inhibition of 14 mm and MIC value 5 × 10(-3). Overall, Q. castaneifolia may be considered for treatment of the patients suffering from enteric disease.
authors.affiliation: Department of Microbiology, Science and Research Branch, Islamic Azad University, Fars, Iran. dr.bahador@fsriau.ac.ir
authors.forename: N
authors.initials: N
authors.lastname: Bahador
authors.forename: M
authors.initials: M
authors.lastname: Baserisalehi
mesh_terms: D000900:Anti-Bacterial Agents / Q000302:isolation & purification* / Q000494:pharmacology*; D004755:Enterobacteriaceae / Q000187:drug effects*; D006801:Humans; D007492:Iran; D008826:Microbial Sensitivity Tests; D010936:Plant Extracts / Q000302:isolation & purification* / Q000494:pharmacology*; D029963:Quercus / Q000737:chemistry*
chemical_list: D000900:Anti-Bacterial Agents; D010936:Plant Extracts