title: Hepatosplenic T-cell lymphoma is a distinct rare entity: diagnosis by fine-needle aspiration cytology.
abstract: In this brief report, we have described the fine-needle aspiration cytology (FNAC) of a hepatosplenic T-cell lymphoma (HSTCL) in a 60-year-old female patient. The patient complained of fever and heaviness of left upper abdomen. Ultrasound-guided FNAC of the spleen showed immature lymphoid cells, and a diagnosis of primary non-Hodgkin lymphoma of spleen was offered. Subsequently, the patient underwent splenectomy and wedge biopsy of liver that confirmed the cytological diagnosis. The lymphoma cells were positive for CD3 immunostain. Primary hepatosplenic T-cell lymphoma is a rare entity and may often pose diagnostic problems on FNAC.
authors.affiliation: Department of Cytology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
authors.forename: Rajiv
authors.initials: R
authors.lastname: Kumar
authors.forename: Pranab
authors.initials: P
authors.lastname: Dey
authors.forename: Ashim
authors.initials: A
authors.lastname: Das
authors.forename: Manupdesh Singh
authors.initials: MS
authors.lastname: Sachdeva
authors.forename: Subhash
authors.initials: S
authors.lastname: Varma
mesh_terms: D044963:Biopsy, Fine-Needle; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D016399:Lymphoma, T-Cell / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D013160:Splenic Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D014463:Ultrasonography