title: [Thickness of the renal pelvis smooth muscle indicates the postoperative course of ureteropelvic junction obstruction treatment].
abstract: OBJECTIVE
  To investigate the relationship between the histopathologic findings and the postoperative course of children surgically treated for ureteropelvic junction (UPJ) obstruction.
  
  
  METHODS
  Twenty-eight patients operated for unilateral UPJ obstruction from 1998 to 2005 with adequate histopathologic specimens and postoperative follow up were retrospectively reviewed. Specimens were stained using elastic van Geisson to differentiate smooth muscle from collagen and elastin. Postoperative follow up included renal ultrasound (U/S) and diuretic renogram studies.
  
  
  RESULTS
  Twelve patients with mean renal pelvis smooth muscle thickness (mRPSMT) of 136.97 ± 34.17 improved on the 6(th) postoperative month. Nine patients that improved after 9 months postoperatively had mRPSMT=173.61 ± 33.91. The rest 7 patients that improved on the 12(th) postoperative month had mRPSMT=258.78 ± 96.09. Correlation between renal pelvis smooth muscle and time of postoperative improvement was extremely significant (r = 0.7928, p < 0.0001).
  
  
  CONCLUSIONS
  The thickness of the renal pelvis smooth muscle is significantly correlated to the postoperative course of patients with UPJ obstruction and can be used as a prognostic tool for the onset of their improvement.
authors.affiliation: Servicio Secundario de Cirugía Pediátrica, Hospital Universitario Aristotle, Hospital General Papageorgiou, Thessaloniki, Grecia. xkaselas@otenet.gr
authors.forename: C
authors.initials: C
authors.lastname: Kaselas
authors.forename: S
authors.initials: S
authors.lastname: Aggelidou
authors.forename: G
authors.initials: G
authors.lastname: Papouis
authors.forename: C
authors.initials: C
authors.lastname: Kazakis
authors.forename: A
authors.initials: A
authors.lastname: Philippopoulos
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007682:Kidney Pelvis / Q000002:abnormalities / Q000000981:diagnostic imaging / Q000601:surgery / Q000648:ultrastructure*; D008297:Male; D009130:Muscle, Smooth / Q000648:ultrastructure*; D011184:Postoperative Period; D011379:Prognosis; D012189:Retrospective Studies; D016896:Treatment Outcome; D014463:Ultrasonography; D014513:Ureter / Q000002:abnormalities; D014517:Ureteral Obstruction / Q000151:congenital / Q000601:surgery*; D014945:Wound Healing