title: Impact of the vaginal applicator and dummy pellets on the dosimetry parameters of Cs-137 brachytherapy source.
abstract: In this study, dose rate distribution around a spherical 137Cs pellet source, from a low-dose-rate (LDR) Selectron remote afterloading system used in gynecological brachytherapy, has been determined using experimental and Monte Carlo simulation techniques. Monte Carlo simulations were performed using MCNP4C code, for a single pellet source in water medium and Plexiglas, and measurements were performed in Plexiglas phantom material using LiF TLD chips. Absolute dose rate distribution and the dosimetric parameters, such as dose rate constant, radial dose functions, and anisotropy functions, were obtained for a single pellet source. In order to investigate the effect of the applicator and surrounding pellets on dosimetric parameters of the source, the simulations were repeated for six different arrangements with a single active source and five non-active pellets inside central metallic tubing of a vaginal cylindrical applicator. In commercial treatment planning systems (TPS), the attenuation effects of the applicator and inactive spacers on total dose are neglected. The results indicate that this effect could lead to overestimation of the calculated F(r,θ), by up to 7% along the longitudinal axis of the applicator, especially beyond the applicator tip. According to the results obtained in this study, in a real situation in treatment of patients using cylindrical vaginal applicator and using several active pellets, there will be a large discrepancy between the result of superposition and Monte Carlo simulations.
authors.affiliation: School of Mechanical Engineering, Shiraz University, Shiraz, Iran. faghihir@shirazu.ac.ir
authors.forename: Sedigheh
authors.initials: S
authors.lastname: Sina
authors.forename: Reza
authors.initials: R
authors.lastname: Faghihi
authors.forename: Ali S
authors.initials: AS
authors.lastname: Meigooni
authors.forename: Simin
authors.initials: S
authors.lastname: Mehdizadeh
authors.forename: M Amin
authors.initials: MA
authors.lastname: Mosleh Shirazi
authors.forename: Mehdi
authors.initials: M
authors.lastname: Zehtabian
mesh_terms: D000465:Algorithms; D016880:Anisotropy; D001918:Brachytherapy / Q000379:methods* / Q000592:standards; D002588:Cesium Radioisotopes / Q000627:therapeutic use*; D003198:Computer Simulation; D005260:Female; D006801:Humans; D008670:Metals / Q000627:therapeutic use; D009010:Monte Carlo Method; D011879:Radiotherapy Dosage; D013819:Thermoluminescent Dosimetry / Q000379:methods* / Q000592:standards; D014621:Vagina / Q000528:radiation effects*
chemical_list: D002588:Cesium Radioisotopes; D008670:Metals