title: Prospective Changes in Health-Related Quality of Life and Emotional Outcomes in Kidney Transplantation over 6 Years.
abstract: Little is known on long-term outcomes in kidney transplantation. This study evaluated changes and predictors of generic and transplantation-specific health-related quality of life (HQoL) over six years in N = 102 kidney transplant survivors using the Short-form Health Survey-36 and the Transplant Effects questionnaire. Mixed models analysis was used to determine long-term outcomes. Emotional HQoL improved over time: Mental Component score, Mental Health, Energy (Ps = .000). Physical HQoL deteriorated: Physical Component Score (P = .001), Pain (P = .002). LRD transplant recipients had greater decline in physical functioning (P = .003) and PCS (P = .000) compared to cadaver recipients. Worry about the transplant (P = .036) and feelings of responsibility (P = .008) increased significantly over time. Worry about the transplant and perceived ability to work predicted 12.7% and 31.1% in variance in MCS and PCS, respectively. Efforts should be made to maintain HQoL and emotional outcomes with ongoing monitoring and support programs throughout the course of posttransplant care.
authors.affiliation: Department of Psychology, National University of Singapore, 9Arts Link AS402/28, Singapore.
authors.forename: Konstadina
authors.initials: K
authors.lastname: Griva
authors.forename: Jan
authors.initials: J
authors.lastname: Stygall
authors.forename: Juan Hui
authors.initials: JH
authors.lastname: Ng
authors.forename: Andrew
authors.initials: A
authors.lastname: Davenport
authors.forename: Mike J
authors.initials: MJ
authors.lastname: Harrison
authors.forename: Stanton
authors.initials: S
authors.lastname: Newman