title: Steroid-refractory cryptogenic multifocal ulcerous stenosing enteritis.
abstract: Cryptogenic multifocal ulcerous stenosing enteritis (CMUSE) is a rare disease of unclear origin and pathophysiology. Treatment is symptomatic, with no particular medical therapy except for corticosteroids. We describe a patient with steroid-refractory CMUSE. A 25-year-old woman underwent bowel surgery 4 times because of small-bowel obstruction. She was diagnosed with CMUSE. Despite steroid treatment and immunosuppressive therapy, she continued to complain of recurrent gastrointestinal symptoms and persistent anemia. To avoid short-bowel syndrome in our patient, new medical treatment is necessary for steroid-refractory CMUSE.
authors.affiliation: Department of Colon & Rectal Surgery, University of Ulsan College of Medicine and Asan Medical Center, 388-1 Poongnap-2-Dong, Songpa-Ku, Seoul 138-736, Korea.
authors.forename: Chan Wook
authors.initials: CW
authors.lastname: Kim
authors.forename: Chang Sik
authors.initials: CS
authors.lastname: Yu
authors.forename: Yong Sik
authors.initials: YS
authors.lastname: Yoon
authors.forename: Sang Nam
authors.initials: SN
authors.lastname: Yoon
authors.forename: Seok-Byung
authors.initials: SB
authors.lastname: Lim
authors.forename: Jin Cheon
authors.initials: JC
authors.lastname: Kim
mesh_terms: D015746:Abdominal Pain / Q000209:etiology; D000328:Adult; D000740:Anemia / Q000209:etiology / Q000628:therapy; D001803:Blood Transfusion; D003251:Constriction, Pathologic / Q000473:pathology; D004351:Drug Resistance; D004751:Enteritis / Q000473:pathology* / Q000628:therapy; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use*; D006801:Humans; D007413:Intestinal Mucosa / Q000473:pathology; D007415:Intestinal Obstruction / Q000209:etiology / Q000473:pathology; D007421:Intestine, Small / Q000473:pathology* / Q000601:surgery; D007501:Iron / Q000627:therapeutic use; D011239:Prednisolone / Q000627:therapeutic use; D014131:Trace Elements / Q000627:therapeutic use; D014456:Ulcer / Q000473:pathology*
chemical_list: D005938:Glucocorticoids; D014131:Trace Elements; D011239:Prednisolone; D007501:Iron