title: [Smoking impairs endothelial function in ED patients].
abstract: OBJECTIVE
  To determine whether smoking affects the endothelial function of young ED patients with no cardiovascular disease.
  
  
  METHODS
  This study included 69 ED patients (21 smokers and 48 non-smokers) and 16 age-matched normal healthy controls. All underwent measurement of brachial artery flow-mediated vasodilation (FMD) and examinations of blood pressure, cholesterol, triglycerides and glucose.
  
  
  RESULTS
  Brachial artery FMD was remarkably decreased in the ED patients, even more significantly in the smokers ([6.0 +/- 0.8]%) than in the non-smokers ([9.7 +/- 2.5]%) (P < 0.05), as compared with that in the normal healthy controls ([14.0 +/- 2. 5]%, P < 0.05).
  
  
  CONCLUSIONS
  Endothelial function is impaired in ED patients, and is further damaged by smoking.
authors.affiliation: Department of Ultrasound, The First Hospital Affiliated to Sun Yat-sen University, Guangzhou, Guangdong 510080, China.
authors.forename: Feng-juan
authors.initials: FJ
authors.lastname: Yao
authors.forename: Yan-ping
authors.initials: YP
authors.lastname: Huang
authors.forename: Hong
authors.initials: H
authors.lastname: Lin
authors.forename: Dong-hong
authors.initials: DH
authors.lastname: Liu
authors.forename: Rui
authors.initials: R
authors.lastname: Fan
authors.forename: Yan-qiu
authors.initials: YQ
authors.lastname: Liu
authors.forename: Kun
authors.initials: K
authors.lastname: Lu
authors.forename: Chun-hua
authors.initials: CH
authors.lastname: Deng
authors.forename: Xiang-zhou
authors.initials: XZ
authors.lastname: Sun
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D004730:Endothelium, Vascular / Q000503:physiopathology*; D007172:Erectile Dysfunction / Q000503:physiopathology*; D006801:Humans; D018783:Impotence, Vasculogenic / Q000503:physiopathology; D008297:Male; D012907:Smoking; D014664:Vasodilation