title: Cerebral palsy among children born moderately preterm or at moderately low birthweight between 1980 and 1998: a European register-based study.
abstract: OBJECTIVE
  The aim of this study was to describe trends in prevalence, subtypes, and severity among children with cerebral palsy (CP) born moderately preterm (MPT; (gestational age 32-36 wks) or at moderately low birthweight (MLBW; 1500-2499 g) in Europe.
  
  
  METHODS
  We conducted trend analyses of data from 903 children with CP born between 1980 and 1998 who were MPT (gestational age 32-36 wks), taken from 11 registers in the Surveillance of Cerebral Palsy in Europe database and from 1835 children with CP who were born at moderately low birthweight (1500-2499 g), taken from 14 registers in the Surveillance of Cerebral Palsy in Europe database.
  
  
  RESULTS
  The overall annual prevalence of CP in children born MPT varied between 12.2 (95% confidence interval [CI] 8.5-17.1) per 1000 live births in 1983 and 4.5 (95% CI 3.2-6.3) per 1000 in 1997. There was a significant decrease in the prevalence over time adjusted for register, with an annual change in prevalence of -3% (95% CI -5 to -2%). This was due to a decrease in the prevalence of bilateral spastic CP (annual change -5%; 95% CI -7 to -3%).
  
  
  CONCLUSIONS
  There was a trend towards a decrease in the prevalence of CP among children born MPT, but no difference in prevalence among children born at MLBW. Both results may represent an improvement in perinatal and neonatal care.
authors.affiliation: Norwegian Cerebral Palsy Registry, Habilitation Center, Vestfold Hospital, Tønsberg, Norway. guro.andersen@siv.no
authors.forename: Guro L
authors.initials: GL
authors.lastname: Andersen
authors.forename: Pål
authors.initials: P
authors.lastname: Romundstad
authors.forename: Javier
authors.initials: J
authors.lastname: De La Cruz
authors.forename: Kate
authors.initials: K
authors.lastname: Himmelmann
authors.forename: Elodie
authors.initials: E
authors.lastname: Sellier
authors.forename: Christine
authors.initials: C
authors.lastname: Cans
authors.forename: Jennifer J
authors.initials: JJ
authors.lastname: Kurinczuk
authors.forename: Torstein
authors.initials: T
authors.lastname: Vik
mesh_terms: D000293:Adolescent; D000328:Adult; D002547:Cerebral Palsy / Q000453:epidemiology*; D016001:Confidence Intervals; D005060:Europe / Q000453:epidemiology; D005260:Female; D006801:Humans; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D007234:Infant, Premature; D007235:Infant, Premature, Diseases / Q000453:epidemiology*; D008297:Male; D015995:Prevalence; D012042:Registries / Q000706:statistics & numerical data*; D055815:Young Adult