title: Elastomeric polypeptides.
abstract: Elastomeric polypeptides are very interesting biopolymers and are characterized by rubber-like elasticity, large extensibility before rupture, reversible deformation without loss of energy, and high resilience upon stretching. Their useful properties have motivated their use in a wide variety of materials and biological applications. This chapter focuses on elastin and resilin - two elastomeric biopolymers - and the recombinant polypeptides derived from them (elastin-like polypeptides and resilin-like polypeptides). This chapter also discusses the applications of these recombinant polypeptides in the fields of purification, drug delivery, and tissue engineering.
authors.affiliation: Institute for Molecules and Materials, Radboud University Nijmegen, Nijmegen, The Netherlands.
authors.forename: Mark B
authors.initials: MB
authors.lastname: van Eldijk
authors.forename: Christopher L
authors.initials: CL
authors.lastname: McGann
authors.forename: Kristi L
authors.initials: KL
authors.lastname: Kiick
authors.forename: Jan C M
authors.initials: JC
authors.lastname: van Hest
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001672:Biocompatible Materials / Q000737:chemistry* / Q000378:metabolism; D002846:Chromatography, Affinity; D003692:Delayed-Action Preparations / Q000737:chemistry* / Q000378:metabolism; D004337:Drug Carriers / Q000737:chemistry* / Q000378:metabolism; D004548:Elasticity; D004549:Elastin / Q000096:biosynthesis / Q000737:chemistry; D006801:Humans; D019476:Insect Proteins / Q000096:biosynthesis* / Q000737:chemistry; D007313:Insecta; D008969:Molecular Sequence Data; D010455:Peptides / Q000737:chemistry / Q000378:metabolism*; D044367:Phase Transition; D011994:Recombinant Proteins / Q000096:biosynthesis* / Q000737:chemistry; D013696:Temperature; D023822:Tissue Engineering / Q000379:methods*; D014333:Tropoelastin / Q000096:biosynthesis / Q000737:chemistry
chemical_list: D001672:Biocompatible Materials; D003692:Delayed-Action Preparations; D004337:Drug Carriers; D019476:Insect Proteins; D010455:Peptides; D011994:Recombinant Proteins; D014333:Tropoelastin; C030951:resilin; D004549:Elastin