title: Phosphorylation of RNAPII: To P-TEFb or not to P-TEFb?
abstract: The C-terminal domain of RNA polymerase II undergoes a cycle of phosphorylation which allows it to temporally couple transcription with transcription-associated processes. The characterization of hitherto unrecognized metazoan elongation phase CTD kinase activities expands our understanding of this coupling. We discuss the circumstances that delayed the recognition of these kinase activities.
authors.affiliation: Department of Biochemistry; Duke Center for RNA Biology; Duke University Medical Center; Durham, NC USA.
authors.forename: Bartlomiej
authors.initials: B
authors.lastname: Bartkowiak
authors.forename: Arno L
authors.initials: AL
authors.lastname: Greenleaf