title: Treatment of mixed urinary incontinence in women.
abstract: OBJECTIVE
  Deciding on an optimal therapy for mixed urinary incontinence (MUI) is challenging, as a single-treatment modality may be inadequate for alleviating both the urge and stress component. A MEDLINE search was conducted regarding English-language literature pertaining to the treatment for MUI focusing on literature within the last 18 months.
  
  
  RESULTS
  Behavioral therapy and lifestyle modification, such as moderate weight loss and caffeine reduction, should be considered first-line options for all women with MUI. The addition of pelvic floor muscle therapy may have an additional salutary effect. Treatment of the urge component with antimuscarinics is effective; however, the stress component is likely to persist after therapy. Treatment with vaginal estrogen cream may help in the short-term, but long-term benefits are unknown. Anti-incontinence surgery may have a positive impact on both the stress and urge components of MUI; however, it appears that women with MUI may have lower cure rates compared to women with pure stress urinary incontinence.
  
  
  CONCLUSIONS
  The optimum treatment of MUI may often require multiple treatment modalities. Although surgery may often have a positive impact on both components, its routine implementation should be approached with caution and patients should be carefully selected and counseled.
authors.affiliation: Department of Urology, Louisiana State University Health Sciences Center, Shreveport, Louisiana, USA.
authors.forename: Alex
authors.initials: A
authors.lastname: Gomelsky
authors.forename: Roger R
authors.initials: RR
authors.lastname: Dmochowski
mesh_terms: D005081:Exercise Therapy; D005260:Female; D006801:Humans; D018727:Muscarinic Antagonists / Q000627:therapeutic use*; D016032:Randomized Controlled Trials as Topic; D040242:Risk Reduction Behavior; D014550:Urinary Incontinence, Stress / Q000523:psychology / Q000534:rehabilitation* / Q000628:therapy; D053202:Urinary Incontinence, Urge / Q000523:psychology / Q000534:rehabilitation* / Q000628:therapy; D015431:Weight Loss
chemical_list: D018727:Muscarinic Antagonists