title: Successful outcome in a HIV infected child presenting with Pre-B Acute Lymphoblastic Leukemia.
abstract: The present case is a 5 y old child with Pre-B Acute Lymphoblastic Leukemia (ALL), presenting with fever, pallor, purpuric spots, hepato-splenomegaly and lymphadenopathy of 20 d duration. During re-induction chemotherapy, he developed atypical skin lesions diagnosed as Varicella Zoster infection. He and his parents tested positive for anti HIV antibody. He entered complete remission and Anti-retroviral therapy (ART) along with maintenance chemotherapy has been initiated 3 mon ago. Acute leukemia is rare in HIV and probably this is the first case of Pre-B Acute Leukemia in association with perinatally transmitted HIV.
authors.affiliation: Department of Pediatric Medicine, Medical College Kolkata, 88, College Street, Kolkata 700073, West Bengal, India. dr.moumitaghosh@gmail.com
authors.forename: Moumita
authors.initials: M
authors.lastname: Ghosh
authors.forename: Mukut
authors.initials: M
authors.lastname: Banerjee
authors.forename: Swapna
authors.initials: S
authors.lastname: Chakraborty
authors.forename: Subhasish
authors.initials: S
authors.lastname: Bhattacharyya
mesh_terms: D002675:Child, Preschool; D015658:HIV Infections / Q000150:complications* / Q000188:drug therapy*; D006562:Herpes Zoster / Q000150:complications*; D006801:Humans; D008297:Male; D015452:Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications*; D016896:Treatment Outcome