title: Tuberculous damaged lung in a child.
abstract: Tuberculosis (TB) remains the "great pretender." We report the case of a 10-year-old female, who presented with a mass in the left chest that was suspected initially to be a tumor. This was later confirmed to be tuberculous in nature, with dissemination to the liver. A large granuloma eventually replaced the left lung, leaving her with "tuberculous destroyed lung" (TDL), an extremely rare, life-threatening sequela of the disease. We review the pathophysiology, radiologic findings, and management options, which includes pneumonectomy, for this seldom seen but preventable condition.
authors.affiliation: Department of Pediatrics and Child Health, Pediatric Respirology, University of Manitoba, Winnipeg, Manitoba, Canada. caraneta@cc.umanitoba.ca
authors.forename: Raquel
authors.initials: R
authors.lastname: Consunji-Araneta
authors.forename: Rick
authors.initials: R
authors.lastname: Higgins
authors.forename: Gefei
authors.initials: G
authors.lastname: Qing
authors.forename: Lamya
authors.initials: L
authors.lastname: Bouhasan
mesh_terms: D000995:Antitubercular Agents / Q000627:therapeutic use; D002648:Child; D004359:Drug Therapy, Combination; D004977:Ethambutol / Q000627:therapeutic use; D005260:Female; D006099:Granuloma / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000188:drug therapy; D006801:Humans; D007538:Isoniazid / Q000627:therapeutic use; D008168:Lung / Q000000981:diagnostic imaging; D008175:Lung Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging; D009169:Mycobacterium tuberculosis / Q000187:drug effects / Q000302:isolation & purification; D011718:Pyrazinamide / Q000627:therapeutic use; D011859:Radiography; D012293:Rifampin / Q000627:therapeutic use; D016896:Treatment Outcome; D014386:Tuberculosis, Hepatic / Q000175:diagnosis* / Q000188:drug therapy; D014397:Tuberculosis, Pulmonary / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000188:drug therapy
chemical_list: D000995:Antitubercular Agents; D011718:Pyrazinamide; D004977:Ethambutol; D007538:Isoniazid; D012293:Rifampin