title: [Gender-related differences in pathological characteristics of upper urinary tract urothelial carcinoma: analysis of 597 cases].
abstract: OBJECTIVE
  To assess the sex differences in pathologic characteristics of Chinese patients with upper urinary tract urothelial carcinoma (UUTUC).
  
  
  METHODS
  Between January 2004 and December 2010, 597 patients (253 men and 344 women) underwent surgical management at Peking University First Hospital for pathologically proven UUTUC. We reviewed pathological data from these patients, and used univariate analysis to determine sex differences.
  
  
  RESULTS
  Of the 597 consecutive cases, mean age was 67 years ranging from 20 to 94 years. Univariate analyses showed that female patients had less proportion of large tumor (P=0.017), local advanced tumor (P<0.001) and lymph node metastasis (P=0.022). No significant sex-related differences were found in the age, tumor grade, and tumor number.
  
  
  CONCLUSIONS
  In Chinese UUTUC patients, female patients were more common. Females are less likely to have more advanced pathologic stage than males.
authors.affiliation: Department of Urology, Peking University First Hospital; Institute of Urology, Peking University, Beijing 100034, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Yu
authors.forename: Ya-yuan
authors.initials: YY
authors.lastname: Zhao
authors.forename: Qi
authors.initials: Q
authors.lastname: Shen
authors.forename: Xin-yu
authors.initials: XY
authors.lastname: Yang
authors.forename: Qun
authors.initials: Q
authors.lastname: He
authors.forename: Yi
authors.initials: Y
authors.lastname: Song
authors.forename: Jie
authors.initials: J
authors.lastname: Jin
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002295:Carcinoma, Transitional Cell / Q000473:pathology*; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012737:Sex Factors; D014516:Ureteral Neoplasms / Q000473:pathology*; D055815:Young Adult