title: Low frequency of endemic patient-to-patient transmission of antibiotic-resistant gram-negative bacilli in a pediatric intensive care unit.
abstract: We sought to determine the frequency of horizontal transmission of antibiotic-resistant gram-negative bacilli (ARGNB) in a pediatric intensive care unit during a nonoutbreak period. Among 5,300 admissions over 39 consecutive months, 13 ARGNB clusters involving 35 children were identified by pulsed-filed gel electrophoresis analysis, which suggests that person-to-person transmission was uncommon.
authors.affiliation: Department of Pediatrics, Case Western Reserve University School of Medicine, Cleveland, OH, USA. joan.zoltanski2@uhhospitals.org
authors.forename: Joan
authors.initials: J
authors.lastname: Zoltanski
authors.forename: Michael
authors.initials: M
authors.lastname: Dul
authors.forename: Mary Ann
authors.initials: MA
authors.lastname: O'Riordan
authors.forename: Jeffrey
authors.initials: J
authors.lastname: Blumer
authors.forename: Philip
authors.initials: P
authors.lastname: Toltzis
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D003428:Cross Infection / Q000635:transmission*; D024901:Drug Resistance, Multiple, Bacterial; D016521:Electrophoresis, Gel, Pulsed-Field; D004755:Enterobacteriaceae / Q000235:genetics; D004756:Enterobacteriaceae Infections / Q000635:transmission; D005260:Female; D016905:Gram-Negative Bacterial Infections / Q000635:transmission*; D006801:Humans; D007223:Infant; D015278:Intensive Care Units, Pediatric; D008297:Male; D011552:Pseudomonas Infections / Q000635:transmission; D011550:Pseudomonas aeruginosa / Q000235:genetics; D020615:Stenotrophomonas maltophilia / Q000235:genetics; D055815:Young Adult