title: Tolerance induction by allogeneic hematopoietic stem cells.
abstract: In this issue of Cell Stem Cell, Zheng et al. (2011) report that HSCs expressing PD-L1 display enhanced engraftment in irradiated allogeneic recipients. Independently in Nature, Fujisaki et al. (2011) observe allogeneic HSCs persisting in proximity to regulatory T cells in nonirradiated recipients, further connecting HSCs and immune tolerance.
authors.affiliation: Center for Cell Engineering, Molecular Pharmacology and Chemistry Program, Memorial Sloan-Kettering Cancer Center (MSKCC), New York, NY 10065, USA.
authors.forename: Maud
authors.initials: M
authors.lastname: Condomines
authors.forename: Michel
authors.initials: M
authors.lastname: Sadelain