title: [Determination of synephrine and arecoline contents in Xiao'er Xiaoji Zhike oral liquid].
abstract: OBJECTIVE
  To develop a HPLC method for the determination of synephrine and arecoline contents in Xiao'er Xiaoji Zhike oral liquid.
  
  
  METHODS
  The analysis was performed on a Symmetry C18 column (4.6 mm x 250 mm, 5 microm) eluted with acetonitrile-methanol-0.1% acetic acid solution (containing potassium dihydrogen phosphate 0.6 g and SDS 1.0 g per 1 000 mL) (15: 30: 55) as mobile phase. The detection wavelength was set at 215 nm.
  
  
  RESULTS
  The synephrine and arecoline concentrations had good linear relationship between 0.281 5-2.815 and 0.040 16-0.401 6 microg (r > 0.999 7), and the average recoveries of the two compounds were 97.1% (RSD 1.4%) and 100% (RSD 1.3%), respectively.
  
  
  CONCLUSIONS
  The method is simple, accurate and sensitive.
authors.affiliation: Hubei Institute for Food and Drug Control, Wuhan 430064, China. shkyjs@163.com
authors.forename: Sihe
authors.initials: S
authors.lastname: Kang
mesh_terms: D001115:Arecoline / Q000032:analysis*; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D004365:Drugs, Chinese Herbal / Q000032:analysis*; D013578:Synephrine / Q000032:analysis*
chemical_list: D004365:Drugs, Chinese Herbal; D001115:Arecoline; D013578:Synephrine