title: [Darier-White disease treated with oral isotretinoin].
abstract: Darier-White Disease (DWD) is an autosomal dominant disorder, described by Darier and White in 1889, characterized by abnormal keratinization in the epidermis, nails and mucosae. We present the case of a 16-year-old, male patient, with clinically and histologically confirmed DWD treated with oral isotretinoin (0.7 mg/kg/day) for six months, with good response. We recommend an optional therapeutic treatment for chronic, itchy, recalcitrant lesions with oral retinoids.
authors.affiliation: Servicio de Dermatología, Hospital Universitario Austral, Argentina. leimer@cas.austral.edu.ar
authors.forename: Lena
authors.initials: L
authors.lastname: Eimer
authors.forename: César
authors.initials: C
authors.lastname: Lagodin
authors.forename: Paula
authors.initials: P
authors.lastname: Bonavia
authors.forename: Matías
authors.initials: M
authors.lastname: Stringa
authors.forename: Ignacio
authors.initials: I
authors.lastname: Rébora
authors.forename: Javier
authors.initials: J
authors.lastname: Anaya
mesh_terms: D000284:Administration, Oral; D000293:Adolescent; D007644:Darier Disease / Q000188:drug therapy*; D003879:Dermatologic Agents / Q000008:administration & dosage*; D006801:Humans; D015474:Isotretinoin / Q000008:administration & dosage*; D008297:Male
chemical_list: D003879:Dermatologic Agents; D015474:Isotretinoin