title: Synthesis of 1,5-benzothiazepine derivatives bearing 2-phenoxy-quinoline moiety via 1,3-diplolar cycloaddition reaction.
abstract: A series of 1,5-benzothiazepine derivatives were synthesized by the reaction of 1,5-benzothiazepine containing 2-phenoxy-quinoline with benzohydroximinoyl chlorides and hydrazonoyl chlorides at room temperature. The structures of these novel compounds were confirmed by spectrum, elemental, and X-ray crystallographic analysis.
authors.affiliation: College of Material, Chemistry and Chemical Engineering, Hangzhou Normal University, Hangzhou, 310036 Zhejiang, People's Republic of China.
authors.forename: Zhi-Qiang
authors.initials: ZQ
authors.lastname: Dong
authors.forename: Fang-Ming
authors.initials: FM
authors.lastname: Liu
authors.forename: Feng
authors.initials: F
authors.lastname: Xu
authors.forename: Zai-Liang
authors.initials: ZL
authors.lastname: Yuan
mesh_terms: D060326:Chemistry Techniques, Synthetic / Q000379:methods*; D015195:Drug Design; D010069:Oxadiazoles / Q000737:chemistry; D011804:Quinolines / Q000737:chemistry*; D013841:Thiazepines / Q000138:chemical synthesis* / Q000737:chemistry*; D014230:Triazoles / Q000737:chemistry
chemical_list: C106746:1,5-benzothiazepine; D010069:Oxadiazoles; D011804:Quinolines; D013841:Thiazepines; D014230:Triazoles; C037219:quinoline