title: Differences in prognostic factors between early and advanced gastric cancer.
abstract: OBJECTIVE
  The aim of this study was to assess any differences in the prognostic factors affecting long term survival in early gastric cancer (EGC) and advanced gastric cancer (AGC).
  
  
  METHODS
  The prognostic factors affecting long term survival between EGC and AGC were evaluated.
  
  
  RESULTS
  Based on the result of multivariate analysis, the variables related with poor prognosis in patient with EGC were ages of more than 60 (p=0.003, Relative risk [RR]:2.683) and more than 7 lymph nodes with metastasis (p=0.001, RR:12.129). The relevant variables in AGC were the presence of more than 7 lymph nodes with metastasis (p=0.002, RR:2.491), lymphovascular invasion (p=0.038, RR:1.476) and tumor depth (serosa ; p<0.001, RR:3.493, adjacent structure; p=0.005, RR:3.013).
  
  
  CONCLUSIONS
  The prognostic factors affecting long term survival are a little different between the patients with EGC and AGC. Age of more than 60 years is one of the prognostic factors affecting long term survival in patients with EGC, but not with AGC. In AGC, lymphovascular invasion and tumor depth are prognostic factors but not in EGC.
authors.affiliation: Department of Surgery, Hallym University College of Medicine, Anyang, Korea.
authors.forename: Byung Seup
authors.initials: BS
authors.lastname: Kim
authors.forename: Sung Wook
authors.initials: SW
authors.lastname: Cho
authors.forename: Soo Kee
authors.initials: SK
authors.lastname: Min
authors.forename: Bong Hwa
authors.initials: BH
authors.lastname: Lee
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011379:Prognosis; D012189:Retrospective Studies; D013274:Stomach Neoplasms / Q000737:chemistry / Q000401:mortality* / Q000473:pathology; D015996:Survival Rate; D016159:Tumor Suppressor Protein p53 / Q000032:analysis
chemical_list: D016159:Tumor Suppressor Protein p53