title: Treatment of status epilepticus with plasmapheresis in a patient with thrombotic thrombocytopenic purpura.
abstract: Thrombotic thrombocytopenic purpura (TTP) is a syndrome with numerous neurological manifestations including altered mental status and seizures. However, status epilepticus (SE) has rarely been reported in this condition. Signs may be transient or fluctuate; however, permanent deficits do occur. Its prognosis was once considered uniformly poor, with a high mortality rate. Since the introduction of plasma infusions and exchanges, the prognosis of the disease has improved dramatically; remissions now occur in 80-90% of patients. Altered mental status in TTP often resolves with plasmapheresis. Likewise, we successfully treated a patient with thrombotic thrombocytopenic purpura (TTP) with pronounced clinical effects of status epilepticus with plasmapheresis and steroid treatment.
authors.affiliation: Department of 2nd Internal Medicine, Izmir Bozyaka Training and Research Hospital, Izmir, Turkey. obilgir2001@yahoo.com
authors.forename: Oktay
authors.initials: O
authors.lastname: Bilgir
authors.forename: Ferda
authors.initials: F
authors.lastname: Bilgir
authors.forename: Mehmet
authors.initials: M
authors.lastname: Calan
authors.forename: Levent
authors.initials: L
authors.lastname: Kebapcilar
authors.forename: Baris
authors.initials: B
authors.lastname: Pamuk
authors.forename: Arif
authors.initials: A
authors.lastname: Yuksel
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D010956:Plasmapheresis; D011379:Prognosis; D011697:Purpura, Thrombotic Thrombocytopenic / Q000175:diagnosis / Q000628:therapy*; D013226:Status Epilepticus / Q000628:therapy*
chemical_list: D000305:Adrenal Cortex Hormones