title: Powdered lipid nano and microparticles: production and applications.
abstract: This review details articles and recent patents in an emerging topic called powdered form of nano- and microparticles. Solid lipid particles were developed in the early 1990s and since, they have been considered as promising drug delivery systems, especially in providing a sustained release profile of the encapsulated drug. This kind of drug delivery system has several advantages, due to its physiological composition. It is generally well tolerated by the human body and are relatively stable during storage in comparison with other carriers like liposomes. The description of these powdered lipid particles, their different production processes and their applications are the focus of the article.
authors.affiliation: Laboratory of Pharmaceutical Technology, University of Liège, Liège, Belgium.
authors.forename: Amandine
authors.initials: A
authors.lastname: Berton
authors.forename: Géraldine
authors.initials: G
authors.lastname: Piel
authors.forename: Brigitte
authors.initials: B
authors.lastname: Evrard
mesh_terms: D000818:Animals; D003692:Delayed-Action Preparations / Q000008:administration & dosage / Q000737:chemistry; D004339:Drug Compounding / Q000639:trends; D016503:Drug Delivery Systems / Q000639:trends; D004355:Drug Stability; D005079:Excipients / Q000737:chemistry; D018014:Gene Transfer Techniques / Q000639:trends; D006801:Humans; D008055:Lipids / Q000737:chemistry*; D053758:Nanoparticles / Q000737:chemistry*; D010330:Patents as Topic; D011208:Powders
chemical_list: D003692:Delayed-Action Preparations; D005079:Excipients; D008055:Lipids; D011208:Powders