title: Early outcome of an implant system with a resorbable adhesive calcium-phosphate coating--a prospective clinical study in partially dentate patients.
abstract: This study aims to investigate the early outcome of a dental implant with bioactive calcium-phosphate (CaP) coating in the first year of usage in different clinical indications in partially edentulous patients, after early and delayed prosthetic loading. Therefore, in a prospective follow-up study, the cumulative survival and success rate of a conical, self-drilling and self-tapping implant system after 6 months and 1 year post-insertion was evaluated. A total of 311 CaP-coated implants were placed in 124 patients. Seventy-two implants in clinical high-quality bone situation were loaded after 2 weeks post-insertion with the definite restoration; the rest after 6 months. The indication for implant placement was treatment of partial dentate mandible and maxilla. One hundred sixty-three implants were placed in the posterior mandible, 117 in the posterior maxilla. In the frontal maxilla, 25 implants and in the frontal mandible, eight implants were used. In 126 cases (36%), bone augmentation procedures (guided bone regeneration and sinus lift) were performed concomitant with implant placement. The difference between primary and secondary stability (implant stability quotient (ISQ), Periotest, insertion torque), peri-implant clinical parameter as well as survival and success criteria were evaluated. In total, ISQ mean values after 6 months were higher than after implant placement. Periotest values increased in the period of the first 6 months and remained constant afterwards. After 6 months of insertion, the mean bone loss was 0.051 mm. After 12 months, a bone gain with a mean of +0.016 mm was observed; implants in the posterior maxilla showed significant less bone resorption than implants in the posterior mandible (p < 0.0001). In the most of the implants (74%), clinical normal gingival tissue could be observed. In 24%, a mild inflammation was analysed. In 35 implants, a provocation of peri-implant bleeding was possible. In the early loading group, no implant failure was seen. Altogether, one implant in D4 bone has been lost. The cumulative survival rate summed up to 99.7%. In general, implant success assessment analysis according to Albrektsson and Buser displayed success in 99.7% of the implants. With respect to the patient selection including 124 implants with minor and major augmentations as well as early loading prosthetic function, the 1-year clinical use of the studied implant system with CaP coating showed good results, comparable to that of conventional implants without a specific coating. After 1 year, neither special disadvantages nor benefits of CaP-coated implants could be evaluated. Long-term results are further needed.
authors.affiliation: Department of Oral and Maxillofacial Surgery, University Medical Centre Mainz, Augustusplatz 2, 55131 Mainz, Germany. vpalarie@gmail.com
authors.forename: Victor
authors.initials: V
authors.lastname: Palarie
authors.forename: Constantin
authors.initials: C
authors.lastname: Bicer
authors.forename: Karl M
authors.initials: KM
authors.lastname: Lehmann
authors.forename: Mohammad
authors.initials: M
authors.lastname: Zahalka
authors.forename: Florian G
authors.initials: FG
authors.lastname: Draenert
authors.forename: Peer W
authors.initials: PW
authors.lastname: Kämmerer
mesh_terms: D000293:Adolescent; D000328:Adult; D016301:Alveolar Bone Loss / Q000209:etiology; D000540:Alveolar Ridge Augmentation / Q000379:methods; D015519:Bone Density / Q000502:physiology; D016723:Bone Remodeling / Q000502:physiology; D002130:Calcium Phosphates / Q000737:chemistry*; D020099:Coated Materials, Biocompatible / Q000737:chemistry*; D015921:Dental Implants; D003774:Dental Plaque Index; D017267:Dental Prosthesis Design; D019094:Dental Prosthesis, Implant-Supported; D019232:Dental Restoration Failure; D005260:Female; D005500:Follow-Up Studies; D016557:Guided Tissue Regeneration, Periodontal / Q000379:methods; D006801:Humans; D057893:Immediate Dental Implant Loading / Q000379:methods; D007576:Jaw, Edentulous, Partially / Q000534:rehabilitation / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D016348:Osseointegration / Q000502:physiology; D010512:Periodontal Index; D011446:Prospective Studies; D059546:Sinus Floor Augmentation / Q000379:methods; D013499:Surface Properties; D016019:Survival Analysis; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D002130:Calcium Phosphates; D020099:Coated Materials, Biocompatible; D015921:Dental Implants; C020243:calcium phosphate