title: Central pontine and extrapontine myelinolysis: a rare and fatal complication after liver transplantation.
abstract: Central pontine myelinolysis (CPM) may be more prevalent after liver transplantation (OLT). Central pontine and extrapontine myelinolysis (CPEM) is rare. The occurence of CPM may be associated with hyponatremia, a rapid rise in serum sodium concentrations, postoperatively increased plasma osmolality, and the duration of the operation. Only 1 patient had abnormal sodium levels before LT. No abnormalities were detected in immunosuppressive drug blood levels. The aim of this paper was to report our experience with CPEM among LT patients.
authors.affiliation: Liver Transplant Unit, Department of Surgery, Virgen de la Arrixaca University Hospital, Murcia, Spain. cascalex@yahoo.es
authors.forename: P
authors.initials: P
authors.lastname: Cascales Campos
authors.forename: P
authors.initials: P
authors.lastname: Ramirez
authors.forename: R
authors.initials: R
authors.lastname: Gonzalez
authors.forename: J A
authors.initials: JA
authors.lastname: Pons
authors.forename: M
authors.initials: M
authors.lastname: Miras
authors.forename: F
authors.initials: F
authors.lastname: Sanchez Bueno
authors.forename: R
authors.initials: R
authors.lastname: Robles
authors.forename: P
authors.initials: P
authors.lastname: Parrilla
mesh_terms: D000368:Aged; D005260:Female; D006801:Humans; D007010:Hyponatremia / Q000209:etiology; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D016031:Liver Transplantation / Q000009:adverse effects* / Q000401:mortality; D008297:Male; D008875:Middle Aged; D017590:Myelinolysis, Central Pontine / Q000097:blood / Q000209:etiology* / Q000401:mortality / Q000628:therapy; D011379:Prognosis; D012189:Retrospective Studies; D012964:Sodium / Q000097:blood; D013030:Spain; D016896:Treatment Outcome
chemical_list: D007166:Immunosuppressive Agents; D012964:Sodium