title: Obstructive hydrocephalus in adult patients: the Louisiana State University Health Sciences Center-Shreveport experience with ventriculoperitoneal shunts.
abstract: OBJECTIVE
  Placement of ventriculoperitoneal shunt is a well-accepted neurosurgical procedure for the management of obstructive hydrocephalus. The purpose of this study is to evaluate our long-term experience in the management of obstructive hydrocephalus in adult patients with ventriculoperitoneal shunts.
  
  
  METHODS
  Adult patients who underwent ventriculoperitoneal shunt placement for obstructive hydrocephalus from October 1990 to October 2009 were included in this study. Medical charts, operative reports, imaging studies, and clinical follow-up evaluations were reviewed and analyzed retrospectively.
  
  
  RESULTS
  A total of 289 adult patients with the median age of 45.8 years were included. The mean and median follow-up time was 45 and 21 months, respectively, after the initial shunt surgery. Among the patients, 51% were men and 65% were white. The most common etiologies included tumors and cysts (45%), postcraniotomy (16%), post-traumatic (15%), and other (24%). Overall shunt revision rate was 37%, and most shunt revisions (28%) occurred within the first six months. The median time to first shunt revision was 5.95 months (range, 3.07-15.98 months). Patients with tumors experienced a significantly lower shunt revision rate and a higher median time to first shunt revision than patients without tumors. The major causes of shunt revision include obstruction (13.8%), infection (6.3%), old shunt dysfunction (16.4%), proximal shunt complication (12.7%), and other (19%).
  
  
  CONCLUSIONS
  The results of this retrospective study show that ventriculoperitoneal shunting is effective in the management of adult patients with obstructive hydrocephalus. The overall incidence of shunt revision was comparable with previously reported studies in the literature. However, the high proportion of patients experiencing shunt failure after shunt placement is still a concern.
authors.affiliation: Department of Neurosurgery, Louisiana State University Health Sciences Center, Shreveport, Louisiana, USA. kreddy_usa@yahoo.com
authors.forename: G Kesava
authors.initials: GK
authors.lastname: Reddy
authors.forename: Runhua
authors.initials: R
authors.lastname: Shi
authors.forename: A
authors.initials: A
authors.lastname: Nanda
authors.forename: Bharat
authors.initials: B
authors.lastname: Guthikonda
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001932:Brain Neoplasms / Q000150:complications / Q000601:surgery; D004868:Equipment Failure; D005006:Ethnicity; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006849:Hydrocephalus / Q000209:etiology / Q000601:surgery*; D053208:Kaplan-Meier Estimate; D008145:Louisiana; D008297:Male; D008875:Middle Aged; D019635:Neurosurgical Procedures / Q000379:methods* / Q000706:statistics & numerical data; D012086:Reoperation; D012189:Retrospective Studies; D012307:Risk Factors; D012959:Socioeconomic Factors; D016019:Survival Analysis; D017211:Treatment Failure; D016896:Treatment Outcome; D017287:Ventriculoperitoneal Shunt; D055815:Young Adult