title: Olfactory groove meningioma.
abstract: Meningiomas are slow-growing benign tumors believed to originate from arachnoidal cap cells. This article discusses the surgical approaches for resection, especially the transnasal endoscopic approach. Alternative treatment options are primarily used where patients are not surgical candidates or location of recurrence precludes additional surgery. These options include radiotherapy, stereotactic radiosurgery, and chemotherapy. In addition, we discuss the current on going research in molecular targeting agents for meningioma treatment.
authors.affiliation: Department of Otorhinolaryngology-Head and Neck Surgery, University of Pennsylvania School of Medicine, Hospital of the University of Pennsylvania, Ravdin Building 5th Floor, 3400 Spruce Street, Philadelphia, PA 19104, USA. Nithin.Adappa@uphs.upenn.edu
authors.forename: Nithin D
authors.initials: ND
authors.lastname: Adappa
authors.forename: John Y K
authors.initials: JY
authors.lastname: Lee
authors.forename: Alexander G
authors.initials: AG
authors.lastname: Chiu
authors.forename: James N
authors.initials: JN
authors.lastname: Palmer
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D003131:Combined Modality Therapy; D004724:Endoscopy / Q000009:adverse effects / Q000379:methods; D006801:Humans; D008577:Meningeal Neoplasms / Q000175:diagnosis / Q000209:etiology / Q000401:mortality / Q000628:therapy; D008579:Meningioma / Q000175:diagnosis / Q000209:etiology / Q000401:mortality / Q000628:therapy*; D019060:Minimally Invasive Surgical Procedures; D058990:Molecular Targeted Therapy; D018579:Patient Selection; D011839:Radiation, Ionizing; D016634:Radiosurgery / Q000009:adverse effects / Q000379:methods; D011878:Radiotherapy; D012008:Recurrence; D012307:Risk Factors; D015996:Survival Rate; D016896:Treatment Outcome
chemical_list: D000970:Antineoplastic Agents