title: Evaluation of optical clearing with the combined liquid paraffin and glycerol mixture.
abstract: By scanning biological tissues in vivo and in vitro with optical coherence tomography, it is found that liquid paraffin can enhance the percutaneous penetration of glycerol in deep layers of tissue and take synergistically optical clearing effect with glycerol. It is shown from experimental results that 30% - 50% liquid paraffin glycerol solutions have the best enhancement effect. Considering the refractive index of liquid paraffin and its medicinal value, we think liquid paraffin will play an important role in optical clearing as the penetration enhancer of glycerol in future clinical research.
authors.forename: Jingyi
authors.initials: J
authors.lastname: Wang
authors.forename: Yanmei
authors.initials: Y
authors.lastname: Liang
authors.forename: Shu
authors.initials: S
authors.lastname: Zhang
authors.forename: Yueqiao
authors.initials: Y
authors.lastname: Zhou
authors.forename: Haiyang
authors.initials: H
authors.lastname: Ni
authors.forename: Yan
authors.initials: Y
authors.lastname: Li