title: Laparoscopic cholecystostomy and bile duct lavage for treatment of inspissated bile syndrome: a single-center experience.
abstract: BACKGROUND
  We aim to describe our experience of laparoscopic cholecystostomy and bile duct lavage in the treatment of inspissated bile syndrome.
  
  
  METHODS
  Between January 2005 and December 2009, 16 infants with inspissated bile syndrome underwent laparoscopic cholecystostomy and bile duct lavage in our department. They were 7 males and 9 females, aged 40 days to 3 months, with an average of 65±23.4 days. A laparoscopic aided cholecystostomy was done. Cholangiography and bile duct lavage were performed during the operation. One week after the operation, bile duct lavage with saline was repeated every 2 to 3 days. According to bilirubin levels and liver function, the tube was kept for 2-4 weeks.
  
  
  RESULTS
  The level of bilirubin decreased and liver function was greatly improved after bile duct lavage. Direct bilirubin level, aspartate aminotransferase and γ-GT were significantly decreased 1-2 months after the operation compared with those before surgery (P<0.05).
  
  
  CONCLUSIONS
  The treatment strategy for inspissated bile syndrome with laparoscopic cholecystostomy and biliary duct lavage is feasible and effective.
authors.affiliation: Department of Pediatric Surgery, Children's Hospital, Zhejiang University School of Medicine, 57 Zhugan Xiang, Hangzhou, 310003, China.
authors.forename: Zhi-Gang
authors.initials: ZG
authors.lastname: Gao
authors.forename: Min
authors.initials: M
authors.lastname: Shao
authors.forename: Qi-Xing
authors.initials: QX
authors.lastname: Xiong
authors.forename: Jin-Fa
authors.initials: JF
authors.lastname: Tou
authors.forename: Wei-Guang
authors.initials: WG
authors.lastname: Liu
mesh_terms: D017734:Bile Ducts, Extrahepatic; D017081:Cholecystectomy, Laparoscopic; D001651:Cholestasis, Extrahepatic / Q000628:therapy*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D007507:Therapeutic Irrigation