title: Evolving surgical techniques of and indications for corneal transplantation in Ontario from 2000 to 2009.
abstract: OBJECTIVE
  To determine the changes in the leading indications for and the preferred surgical techniques of corneal transplantation in Ontario over a 9-year period.
  
  
  METHODS
  Retrospective review of Eye Bank of Canada (Ontario Division) records.
  
  
  METHODS
  Recipients of corneal transplants performed in Ontario between 2000 and 2009, totaling 6240 patients.
  
  
  METHODS
  Records of all corneal tissues sent for transplantation in Ontario by the Eye Bank of Canada (Ontario Division) from July 1 2000 to June 30 2009 were reviewed. The records consist of recipient information forms completed by surgeons at the time of corneal transplant surgery. Of the 8186 available recipient information forms, 7755 (94.7%) were sufficiently complete to meet the inclusion criteria.
  
  
  RESULTS
  The leading indications for corneal transplantation were pseudophakic corneal edema (28.3%), regraft (21.5%), Fuchs dystrophy (16.6%), and anterior keratoconus (13.8%). Beginning in 2006, there has been a shift in the proportion of corneal transplants performed using Descemet's stripping automated endothelial keratoplasty (DSAEK) and deep anterior lamellar keratoplasty, from 2.4% to 36.1% of all corneal transplants. Concomitantly, DSAEK has replaced penetrating keratoplasty (PKP) as the technique of choice when corneal transplantation is indicated for Fuchs' dystrophy (139 DSAEKs vs. 68 PKPs in 2009) and for pseudophakic corneal edema (118 DSAEKs vs. 115 PKPs in 2009).
  
  
  CONCLUSIONS
  The indications for PKP in this study agree with the North American literature. In recent years, partial-thickness transplants have gained favor over PKP for select indications in Ontario. These changes reflect the future direction of corneal transplantation and will have implications on the supply of and demand for tissues.
authors.affiliation: University of Toronto Faculty of Medicine, ON, Canada.
authors.forename: Corey
authors.initials: C
authors.lastname: Boimer
authors.forename: Kenneth
authors.initials: K
authors.lastname: Lee
authors.forename: Linda
authors.initials: L
authors.lastname: Sharpen
authors.forename: Raneen Shehadeh
authors.initials: RS
authors.lastname: Mashour
authors.forename: Allan R
authors.initials: AR
authors.lastname: Slomovic
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D003316:Corneal Diseases / Q000453:epidemiology* / Q000601:surgery; D016039:Corneal Transplantation / Q000379:methods* / Q000639:trends*; D005125:Eye Banks / Q000706:statistics & numerical data; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D009864:Ontario / Q000453:epidemiology; D012189:Retrospective Studies; D055815:Young Adult