title: [Thinking on dose-effect relationship of Chinese herbal compounds in clinical studies].
abstract: Dose-effect relationship is an important topic as well as difficulties in clinical studies on Chinese herbal compounds. The relevant concepts of the dose-effect relationship, its features, its backgrounds, directions and roles of clinical studies on the dose-effect relationship of Chinese herbal compounds were discussed in this essay. The current state of clinical studies was introduced. The confronting challenges of clinical studies were also analyzed, thus providing references for the establishment of appropriate clinical research methods in line with Chinese medicine features.
authors.affiliation: Center for Evidence-Based Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029.
authors.forename: Hui
authors.initials: H
authors.lastname: Luo
authors.forename: Jian-ping
authors.initials: JP
authors.lastname: Liu
mesh_terms: D004305:Dose-Response Relationship, Drug; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage* / Q000494:pharmacology*; D006801:Humans; D008517:Phytotherapy
chemical_list: D004338:Drug Combinations; D004365:Drugs, Chinese Herbal