title: [Bacteriology of ethmoidal sinus in chronic rhinosinusitis with and without nasal polyps].
abstract: OBJECTIVE
  To compare the bacteriologic features of anterior ethmoidal biopsy specimens between chronic rhinosinusitis without nasal polyps (CRSNP-), chronic rhinosinusitis with nasal polyps(CRSNP+) and control patients.
  
  
  METHODS
  The biopsy specimens obtained during the nasal endoscopic surgery were cultured for aerobic and anaerobic bacteria.
  
  
  RESULTS
  One hundred and nineteen biopsy specimens were processed for homogenization and semiquantitatively bacterial culture of aerobe and anaerobe. Bacterial culture were positive in 104 specimens (total culture-positive rate was 87.4%). The positive rate of aerobe or facultative anaerobe culture were 86.5%, 85.7%, 90.0% in CRSNP- group, CRSNP+ group and control group, respectively. There were no significant differences between 3 groups (P > 0.05). Mixed growth of aerobe and anaerobe bacteria were mainly detected in the biopsy specimens and the positive rate were 78.4%, 81.0% and 85.0% in CRSNP- group, CRSNP+ group and control group. There were no significant differences in 3 groups (P > 0.05). The most common aerobe bacteria found in 3 groups were coagulase-negative staphylococci and corynebacterium species and there were no significant differences between 3 groups (P > 0.05). The positive rate of anaerobic bacteria culture were 78.4%,76.2% and 77.5% in 3 groups. There were no significant differences between the groups (P > 0.05). Propionibacterium and peptostreptococcus species were the most common anaerobes, and there were no significant differences between 3 groups (P > 0.05).
  
  
  CONCLUSIONS
  There are no significant differences in the bacteriologic features of ethmoidal biopsy specimens between CRSNP+, CRSNP- and control patients. Therefore, bacterial infection may not play a key role in the pathogenesis of nasal polyps in CRS patients.
authors.affiliation: Department of Otorhinolaryngology, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi 830001, China.
authors.forename: Abdureyim
authors.initials: A
authors.lastname: Arkin
authors.forename: Kyrm
authors.initials: K
authors.lastname: Arzguli
authors.lastname: Abdurusuli
authors.forename: Xiuqin
authors.initials: X
authors.lastname: Cheng
authors.lastname: Yulitus
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001706:Biopsy; D016022:Case-Control Studies; D002908:Chronic Disease; D005005:Ethmoid Sinus / Q000382:microbiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009298:Nasal Polyps / Q000150:complications / Q000382:microbiology*; D012852:Sinusitis / Q000150:complications / Q000382:microbiology*; D055815:Young Adult