title: Benign transient hyperphosphatasemia in infants and children: a prospective cohort.
abstract: A total of 20 children with benign transient hyperphosphatasemia were prospectively evaluated with no additional investigations recommended except repeat serologic evaluation in 2-3 months. The average age of our patients was 2.5 years (range 1 year 2 months-5 years 10 months). The serum levels of alkaline phosphatase averaged 2383 IU/L (range 1013-5700 IU/L). Levels returned to normal within several months. This condition should be recognized by the clinician in order not to put patients through lengthy, expensive and unnecessary investigations.
authors.affiliation: Pediatric Gastroenterology and Nutrition, The Children's Hospital at Monmouth Medical Center, Long Branch, NJ 07750, USA. JTeitelbaum@SBHCS.com
authors.forename: Jonathan E
authors.initials: JE
authors.lastname: Teitelbaum
authors.forename: Alexandra
authors.initials: A
authors.lastname: Laskowski
authors.forename: Frank P
authors.initials: FP
authors.lastname: Barrows
mesh_terms: D000469:Alkaline Phosphatase / Q000097:blood*; D001842:Bone and Bones / Q000201:enzymology; D002675:Child, Preschool; D015331:Cohort Studies; D005260:Female; D006801:Humans; D007223:Infant; D007527:Isoenzymes / Q000097:blood; D008099:Liver / Q000201:enzymology; D008297:Male; D011446:Prospective Studies; D013997:Time Factors
chemical_list: D007527:Isoenzymes; D000469:Alkaline Phosphatase