title: Clinical features and risk factors for post-partum depression in a large cohort of Chinese women with recurrent major depressive disorder.
abstract: BACKGROUND
  Post partum depression (PPD) is relatively common in China but its clinical characteristics and risk factors have not been studied. We set out to investigate whether known risk factors for PPD could be found in Chinese women.
  
  
  METHODS
  A case control design was used to determine the impact of known risk factors for PPD in a cohort of 1970 Chinese women with recurrent DSM-IV major depressive disorder (MDD). In a within-case design we examined the risk factors for PPD in patients with recurrent MDD. We compared the clinical features of MDD in cases with PPD to those without MDD. Odds ratios were calculated using logistic and ordinal regression.
  
  
  RESULTS
  Lower occupational and educational statuses increased the risk of PPD, as did a history of pre-menstrual symptoms, stressful life events and elevated levels of the personality trait of neuroticism. Patients with PPD and MDD were more likely to experience a comorbid anxiety disorder, had a younger age of onset of MDD, have higher levels of neuroticism and dysthymia.
  
  
  CONCLUSIONS
  Results obtained in this clinical sample may not be applicable to PPD within the community. Data were obtained retrospectively and we do not know whether the correlations we observe have the same causes as those operating in other populations.
  
  
  CONCLUSIONS
  Our results are consistent with the hypothesis that the despite cultural differences between Chinese and Western women, the phenomenology and risk factors for PPD are very similar.
authors.affiliation: Tianjin Anding Hospital, No. 13 Liu Lin Road, Hexi District, Tianjin 300222, PR China.
authors.forename: Tian
authors.initials: T
authors.lastname: Tian
authors.forename: Yihan
authors.initials: Y
authors.lastname: Li
authors.forename: Dong
authors.initials: D
authors.lastname: Xie
authors.forename: Yifeng
authors.initials: Y
authors.lastname: Shen
authors.forename: Jianer
authors.initials: J
authors.lastname: Ren
authors.forename: Wenyuan
authors.initials: W
authors.lastname: Wu
authors.forename: Chengbin
authors.initials: C
authors.lastname: Guan
authors.forename: Zhen
authors.initials: Z
authors.lastname: Zhang
authors.forename: Danning
authors.initials: D
authors.lastname: Zhang
authors.forename: Chengge
authors.initials: C
authors.lastname: Gao
authors.forename: Xiaoming
authors.initials: X
authors.lastname: Zhang
authors.forename: Jinbo
authors.initials: J
authors.lastname: Wu
authors.forename: Hong
authors.initials: H
authors.lastname: Deng
authors.forename: Gang
authors.initials: G
authors.lastname: Wang
authors.forename: Yunshu
authors.initials: Y
authors.lastname: Zhang
authors.forename: Yun
authors.initials: Y
authors.lastname: Shao
authors.forename: Han
authors.initials: H
authors.lastname: Rong
authors.forename: Zhaoyu
authors.initials: Z
authors.lastname: Gan
authors.forename: Yan
authors.initials: Y
authors.lastname: Sun
authors.forename: Bin
authors.initials: B
authors.lastname: Hu
authors.forename: Jiyang
authors.initials: J
authors.lastname: Pan
authors.forename: Yi
authors.initials: Y
authors.lastname: Li
authors.forename: Shufan
authors.initials: S
authors.lastname: Sun
authors.forename: Libo
authors.initials: L
authors.lastname: Song
authors.forename: Xuesheng
authors.initials: X
authors.lastname: Fan
authors.forename: Yi
authors.initials: Y
authors.lastname: Li
authors.forename: Xiaochuan
authors.initials: X
authors.lastname: Zhao
authors.forename: Bin
authors.initials: B
authors.lastname: Yang
authors.forename: Luxian
authors.initials: L
authors.lastname: Lv
authors.forename: Yunchun
authors.initials: Y
authors.lastname: Chen
authors.forename: Xiaoli
authors.initials: X
authors.lastname: Wang
authors.forename: Yuping
authors.initials: Y
authors.lastname: Ning
authors.forename: Shenxun
authors.initials: S
authors.lastname: Shi
authors.forename: Yiping
authors.initials: Y
authors.lastname: Chen
authors.forename: Kenneth S
authors.initials: KS
authors.lastname: Kendler
authors.forename: Jonathan
authors.initials: J
authors.lastname: Flint
authors.forename: Hongjun
authors.initials: H
authors.lastname: Tian
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D002681:China; D015331:Cohort Studies; D015897:Comorbidity; D019052:Depression, Postpartum / Q000175:diagnosis / Q000453:epidemiology*; D003865:Major Depressive Disorder / Q000175:diagnosis / Q000453:epidemiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D012189:Retrospective Studies; D012307:Risk Factors