title: N-6 Substituted Deoxygenated Derivatives of L-like 5'-Noraristeromycin.
abstract: Several N-6 substituted derivatives (4-11) of (+)-4'-deoxy-5'-noraristeromycin (2) and its unsaturated counterpart (3) have been prepared. The derivatives are designed to systematically vary the hydrophobic/hydrophilic balance of the lead compounds. These compounds were evaluated against a large number of viruses but, no significant antiviral activity was observed. Also, no cytotoxicity to host cells was found.
authors.affiliation: Elizabeth City State University, Department of Chemistry, Geology, and Physics Elizabeth city, NC 27909 USA.
authors.forename: Henry
authors.initials: H
authors.lastname: Yu
authors.forename: Tesfaye
authors.initials: T
authors.lastname: Serbessa