title: Metal nitrite: a powerful oxidizing reagent.
abstract: An efficient and simple source of nitroso reagents and their oxidation reactions are described. The combination of a Lewis acid and a metal nitrite was applied to the oxidation of silyl enol ethers. Amino acid and peptide derivatives were easily accessed through in situ C-C bond cleavage of fully substituted silyl enol ethers upon oxidation.
authors.affiliation: Department of Chemistry, The University of Chicago, Illinois 60637, United States.
authors.forename: Mahiuddin
authors.initials: M
authors.lastname: Baidya
authors.forename: Hisashi
authors.initials: H
authors.lastname: Yamamoto
mesh_terms: D000596:Amino Acids / Q000138:chemical synthesis; D008670:Metals / Q000737:chemistry*; D009573:Nitrites / Q000737:chemistry*; D009603:Nitroso Compounds / Q000737:chemistry; D016877:Oxidants / Q000737:chemistry*; D010084:Oxidation-Reduction; D010455:Peptides / Q000138:chemical synthesis
chemical_list: D000596:Amino Acids; D008670:Metals; D009573:Nitrites; D009603:Nitroso Compounds; D016877:Oxidants; D010455:Peptides