title: [Prostatic adenocarcinoma with glomeruloid structure].
abstract: OBJECTIVE
  To investigate the architectural features and frequency of glomeruloid features in pathological section of prostatic adenocarcinoma and evaluate the association between glomerulations and its clinical data.
  
  
  METHODS
  We studied 196 prostatic adenocarcinoma specimens obtained from needle biopsies or radical prostatectomy and their clinical data, and reviewed related literatures.
  
  
  RESULTS
  Three of the 196 cases showed glomeruloid features, the Gleason score of which was 7, 8, and 8, respectively. Of the 3 cases 1 had osseous metastasis and 2 extraprostatic nervus extension. After 5 to 15 months' follow-up, 1 case died and the other 2 still under treatment.
  
  
  CONCLUSIONS
  Glomeruloid structures in the prostate represented an uncommon but distinctive growth pattern that was specific for malignancy. Glomeruloid structures were usually seen in high-grade adenocarcinoma, often with extraprostatic extension.
authors.affiliation: Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology,Wuhan 430030, China.
authors.forename: Zhuo
authors.initials: Z
authors.lastname: Liu
authors.forename: Bao
authors.initials: B
authors.lastname: Chang
authors.forename: Shui-ming
authors.initials: SM
authors.lastname: Guo
authors.forename: Tao
authors.initials: T
authors.lastname: Wang
authors.forename: Ming-chao
authors.initials: MC
authors.lastname: Li
authors.forename: Jun
authors.initials: J
authors.lastname: Yang
authors.forename: Ke
authors.initials: K
authors.lastname: Chen
authors.forename: Wei-min
authors.initials: WM
authors.lastname: Yang
authors.forename: Ji-hong
authors.initials: JH
authors.lastname: Liu
authors.forename: Zhang-qun
authors.initials: ZQ
authors.lastname: Ye
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology*; D000368:Aged; D000369:Aged, 80 and over; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D011471:Prostatic Neoplasms / Q000473:pathology*; D012189:Retrospective Studies