title: CUL4B: trash talking at chromatin.
abstract: In this issue, Nakagawa and Xiong (2011) reveal a mechanism targeting WDR5 for proteolysis dependent on the X-linked mental retardation gene, CUL4B. This provides a link between the stability of a chromatin factor and gene expression implicated in neurological pathogenesis.
authors.affiliation: Department of Biology, Stanford University, Stanford, CA, USA.
authors.forename: Erin M
authors.initials: EM
authors.lastname: Green
authors.forename: Or
authors.initials: O
authors.lastname: Gozani