title: Five-year progression-free survival in 577 patients operated on with laparoscopic radical prostatectomy for localized prostate cancer.
abstract: OBJECTIVE
  Laparoscopic radical prostatectomy (LRP) was introduced in the Department of Urology, Oslo University Hospital, in 2002. The aim of this study was to report mid-term oncology results and survival data.
  
  
  METHODS
  From February 2002 to November 2007, 582 consecutive patients with localized prostate cancer underwent LRP. Data were collected prospectively into a database.
  
  
  RESULTS
  Mean and median follow-up after LRP was 30.3 months (± 15.5) and 36.0 months (range 3-72). Five patients (1%) were lost during follow-up. Two patients died of prostate cancer during the study period and 10 patients died of other causes. The overall positive surgical margin (PSM) rate was 29% and decreased to 13% for the last 100 patients. The overall PSA progression-free survival (PFS) was 85% at 3 years and 73% at 5 years. Gleason score in the tumour specimen, pT stage and surgical margins were statistical significant independent predictors of biochemical PFS.
  
  
  CONCLUSIONS
  These oncology results and 5-year PFS data after LRP are in line with other reports.
authors.affiliation: Department of Urology, Oslo University Hospital, Aker, Oslo, Norway. viktbe@online.no
authors.forename: Viktor
authors.initials: V
authors.lastname: Berge
authors.forename: Rolf Eigil
authors.initials: RE
authors.lastname: Berg
authors.forename: Jon Roar
authors.initials: JR
authors.lastname: Hoff
authors.forename: Nicolai
authors.initials: N
authors.lastname: Wessel
authors.forename: Aud
authors.initials: A
authors.lastname: Svindland
authors.forename: Steinar Johan
authors.initials: SJ
authors.lastname: Karlsen
authors.forename: Lars Magne
authors.initials: LM
authors.lastname: Eri
mesh_terms: D000230:Adenocarcinoma / Q000453:epidemiology / Q000473:pathology / Q000601:surgery*; D000328:Adult; D000368:Aged; D018572:Disease-Free Survival; D005500:Follow-Up Studies; D006801:Humans; D010535:Laparoscopy / Q000379:methods*; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D009664:Norway / Q000453:epidemiology; D011446:Prospective Studies; D011468:Prostatectomy / Q000379:methods*; D011471:Prostatic Neoplasms / Q000453:epidemiology / Q000473:pathology / Q000601:surgery*; D012189:Retrospective Studies; D015996:Survival Rate; D016896:Treatment Outcome