title: [Chemical constituents of aerial parts of Gelsemium elegans].
abstract: OBJECTIVE
  To study the chemical constituents from the aerial parts of Gelsemium elegans.
  
  
  METHODS
  Compounds were isolated and purified by repeated column chromatography, as well as semiprep arative HPLC, and their structures were identified by physicochemical properties and spectroscopic methods, such as NMR and MS.
  
  
  RESULTS
  Sixteen compounds were obtained and identified from G. elegans, including nine alkaloids: koumine (1), gelsenicine (2), 19-(Z)-akuammidine (3), gelsemoxonine(4), gelsemin (5), gelsevirine (6), humantenine (7), 11-methoxygelsemamide (8) and gelegamine D (9). Three megastigmane glycosides: (3R, 5S, 6S, 7E, 9R)-megastigman-7-ene-3, 5, 6, 9-tetrol-9-O-beta-D-glucopyranoside (10), (6R, 7E, 9R)-9-hydroxy-4, 7-megastigmadien-3-one-9-O-[alpha-L-arabinopyranosyl-(1 --> 6)-beta-D-glucopyranoside] (11) and (6S, 7E, 9R) -6, 9-dihydroxy-4, 7-megastigmadien-3-one-9-O-[alpha-L-arabinopyranosyl-(1 --> 6) -beta-D-glucopyranoside] (12). Two flavone C-glycosides: orientin (13) and isorientin (14); one iridoid glycoside, sweroside (15) and one fructoside, n-butyl-alpha-D-fructofuranoside (16).
  
  
  CONCLUSIONS
  Compounds 10-16 were isolated from the genus Gelsemium for the first time.
authors.affiliation: Department of Pharmacognosy, China Pharmaceutical University, Nanjing 210009, China.
authors.forename: Qiuping
authors.initials: Q
authors.lastname: Zhang
authors.forename: Binfeng
authors.initials: B
authors.lastname: Zhang
authors.forename: Guixin
authors.initials: G
authors.lastname: Chou
authors.forename: Zhengtao
authors.initials: Z
authors.lastname: Wang
mesh_terms: D002851:Chromatography, High Pressure Liquid; D004365:Drugs, Chinese Herbal / Q000737:chemistry* / Q000302:isolation & purification; D031450:Gelsemium / Q000737:chemistry*; D013058:Mass Spectrometry; D035261:Plant Components, Aerial / Q000737:chemistry
chemical_list: D004365:Drugs, Chinese Herbal