title: A case of myxofibrosarcoma of the maxilla with difficulty in preoperative diagnosis.
abstract: Myxofibrosarcoma (MFS) is a very rare fibroblast-derived sarcoma that occurs in the head and neck region. Here, we report the case of a 52-year-old man in whom MFS generated from the maxilla and whose beginning of treatment was considerably delayed because he was initially diagnosed as having a benign inflammatory lesion. Because a definite diagnosis was not obtained via 2 independent biopsies, total maxillectomy was used for both diagnosis and treatment. Histopathological and immunohistochemical analyses suggested that the tumor was a low-grade MFS. Because soft tissue tumors in the head and neck region are rare and a definite diagnosis is relatively difficult, surgical excision is indispensable if malignancy of the tumor is suspected.
authors.affiliation: Department of Otolaryngology, Head and Neck Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, 3-3, Nakamichi 1-chome, Higashinari-ku, Osaka, 537-8511, Japan. susumu.nakahara@gmail.com
authors.forename: Susumu
authors.initials: S
authors.lastname: Nakahara
authors.forename: Hirokazu
authors.initials: H
authors.lastname: Uemura
authors.forename: Tomoyuki
authors.initials: T
authors.lastname: Kurita
authors.forename: Motoyuki
authors.initials: M
authors.lastname: Suzuki
authors.forename: Takashi
authors.initials: T
authors.lastname: Fujii
authors.forename: Yasuhiko
authors.initials: Y
authors.lastname: Tomita
authors.forename: Kunitoshi
authors.initials: K
authors.lastname: Yoshino
mesh_terms: D005350:Fibroma / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D005354:Fibrosarcoma / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D006258:Head and Neck Neoplasms / Q000175:diagnosis / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D057234:Preoperative Period