title: [Studies on the chemical constituents of Ligusticum sinense].
abstract: OBJECTIVE
  To study the chemical constituents of Ligusticum sinense.
  
  
  METHODS
  The chemical constituents were isolated and purified by column chromatography on silica gel and Sephadex LH-20; Using spectroscopy methods to elucidate their structures.
  
  
  RESULTS
  Nine compounds were isolated and identified as levistolide A (1), (Z)-3-butylidene-7-hydroxyphthalide (2), senkyunolide B (3), 3-butylphthalide(4), (Z)-ligustilide (5), riligustilide (6), neocnidilide (7), senkyunolide A (8), beta-sitostesol (9).
  
  
  CONCLUSIONS
  Compounds 2 and 3 are obtained from this plant for the first time.
authors.affiliation: Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education & Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
authors.forename: Jia
authors.initials: J
authors.lastname: Wang
authors.forename: Jian-Bo
authors.initials: JB
authors.lastname: Yang
authors.forename: Ai-Guo
authors.initials: AG
authors.lastname: Wang
authors.forename: Teng-Fei
authors.initials: TF
authors.lastname: Ji
authors.forename: Ya-Lun
authors.initials: YL
authors.lastname: Su
mesh_terms: D000447:Aldehydes / Q000737:chemistry / Q000302:isolation & purification*; D001572:Benzofurans / Q000737:chemistry / Q000302:isolation & purification*; D030004:Ligusticum / Q000737:chemistry*; D013058:Mass Spectrometry / Q000379:methods; D015394:Molecular Structure; D010936:Plant Extracts / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D027343:Rhizome / Q000737:chemistry
chemical_list: C437411:7-hydroxyphthalide; D000447:Aldehydes; D001572:Benzofurans; D010936:Plant Extracts; C523615:levistolide A; C027125:3-n-butylphthalide