title: [HIV infection and diabetes: experience and quality of life in patients with two chronic diseases].
abstract: OBJECTIVE
  Diabetes mellitus is frequently associated with HIV infection but there's only limited evidence regarding the control and impact of this co-morbidity. This study aimed to estimate the prevalence of diabetes, compliance with treatment, perception and quality of life of HIV patients with diabetes.
  
  
  METHODS
  We conducted a cross-sectional study among patients treated for diabetes and registered in the DMI2 databasis in a French university hospital in January 2010. Clinical assessment and follow-up data were collected using chart review and self-administered questionnaires. Quality of life (MOS SF-12) and compliance with treatment (simplified medication adherence questionnaire) were assessed using validated scales.
  
  
  RESULTS
  The prevalence of treated diabetes mellitus was 3.9% (29/748, 95% confidence interval, 2.6% to 5.5%). Among these 29 HIV diabetic patients, 93% had a virologic control of HIV infection while only 22% had well-controlled diabetes. Ninety-six percent of patients were scared to die from HIV-which was rated as the main pathology-compared with 71% of patients for diabetes. The mean score for physical quality of life was 43.1 (13.2), which was lower than estimates for overall population. Non-compliance with treatment was reported for 35% of patients.
  
  
  CONCLUSIONS
  Although anti-retroviral treatments turned HIV infection into a chronic disease, patient perception was not altered. This study shows a better control of HIV infection than diabetes. We have to find out ways (e.g. patient education programs, annual multidisciplinary consultation...) to give the patient a global feel for his health thereby improving prognosis and quality of life.
authors.affiliation: Clinique médicale maladies infectieuses et tropicales, centre hospitalier universitaire Grenoble, 38000 Grenoble, France. drcarolinehenry@gmail.com
authors.forename: Caroline
authors.initials: C
authors.lastname: Henry
authors.forename: Patricia
authors.initials: P
authors.lastname: Pavese
authors.forename: Myriam
authors.initials: M
authors.lastname: Blanc
authors.forename: José
authors.initials: J
authors.lastname: Labarère
authors.forename: Pascale
authors.initials: P
authors.lastname: Leclercq
authors.forename: Jean-Paul
authors.initials: JP
authors.lastname: Brion
mesh_terms: D002908:Chronic Disease; D003430:Cross-Sectional Studies; D048909:Diabetes Complications / Q000150:complications* / Q000453:epidemiology*; D003920:Diabetes Mellitus / Q000453:epidemiology*; D005260:Female; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D011788:Quality of Life; D012189:Retrospective Studies