title: Dietary flavonoids: molecular mechanisms of action as anti- inflammatory agents.
abstract: Flavonoids are a large group of polyphenolic compounds, which are ubiquitously expressed in plants. They are grouped according to their chemical structure and function into flavonols, flavones, flavan-3-ols, anthocyanins, flavanones and isoflavones. Many of flavonoids are found in fruits, vegetables and beverages. Flavonoids have been demonstrated to have advantageous effects on human health because their anti-allergic, anti-inflammatory, anti-platelet aggregation, anti-tumor and anti-oxidant behavior. This report reviews the current knowledge on the molecular mechanisms of action of flavonoids as anti-inflammatory agents and also discusses the relevant patents.
authors.affiliation: Department of Experimental Medicine and Biochemical Sciences, University of Rome Tor Vergata , Via Montpellier 1, 00133 Rome, Italy. bei@med.uniroma2.it
authors.forename: Laura
authors.initials: L
authors.lastname: Marzocchella
authors.forename: Massimo
authors.initials: M
authors.lastname: Fantini
authors.forename: Monica
authors.initials: M
authors.lastname: Benvenuto
authors.forename: Laura
authors.initials: L
authors.lastname: Masuelli
authors.forename: Ilaria
authors.initials: I
authors.lastname: Tresoldi
authors.forename: Andrea
authors.initials: A
authors.lastname: Modesti
authors.forename: Roberto
authors.initials: R
authors.lastname: Bei
mesh_terms: D000818:Animals; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D000975:Antioxidants / Q000627:therapeutic use*; D004032:Diet; D005419:Flavonoids / Q000008:administration & dosage / Q000737:chemistry / Q000627:therapeutic use*; D005638:Fruit / Q000737:chemistry; D006801:Humans; D006967:Hypersensitivity / Q000188:drug therapy*; D009369:Neoplasms / Q000188:drug therapy*; D010330:Patents as Topic; D010944:Plants; D014675:Vegetables / Q000737:chemistry
chemical_list: D000893:Anti-Inflammatory Agents; D000975:Antioxidants; D005419:Flavonoids