title: Derivatives of R-aminocarnitine without ammonium moiety as liver carnitine palmitoyltransferase I (L-CPT I) inhibitors.
authors.affiliation: Chemistry & Analytical Department, Sigma-Tau S.p.A. Via Pontina Km 30.400, 00040 Pomezia, Italy. emanuela.tassoni@sigma-tau.it
authors.forename: Emanuela
authors.initials: E
authors.lastname: Tassoni
authors.forename: Roberto
authors.initials: R
authors.lastname: Conti
authors.forename: Grazia
authors.initials: G
authors.lastname: Gallo
authors.forename: Silvia
authors.initials: S
authors.lastname: Vincenti
authors.forename: Lucilla
authors.initials: L
authors.lastname: Mastrofrancesco
authors.forename: Tiziana
authors.initials: T
authors.lastname: Brunetti
authors.forename: Walter
authors.initials: W
authors.lastname: Cabri
authors.forename: Fabio
authors.initials: F
authors.lastname: Giannessi
mesh_terms: D000284:Administration, Oral; D000818:Animals; D001622:Betaine / Q000031:analogs & derivatives* / Q000737:chemistry; D002331:Carnitine / Q000737:chemistry*; D002334:Carnitine O-Palmitoyltransferase / Q000037:antagonists & inhibitors*; D004353:Drug Evaluation, Preclinical; D004791:Enzyme Inhibitors / Q000008:administration & dosage / Q000737:chemistry* / Q000494:pharmacology*; D007004:Hypoglycemic Agents / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology; D051379:Mice; D008815:Mice, Inbred Strains; D008929:Mitochondria, Heart / Q000187:drug effects / Q000201:enzymology; D008930:Mitochondria, Liver / Q000187:drug effects / Q000201:enzymology; D000644:Quaternary Ammonium Compounds / Q000737:chemistry; D051381:Rats
chemical_list: D004791:Enzyme Inhibitors; D007004:Hypoglycemic Agents; D000644:Quaternary Ammonium Compounds; D001622:Betaine; C045761:emeriamine; D002334:Carnitine O-Palmitoyltransferase; D002331:Carnitine