title: [Clinical efficacy and safety of percutaneous nephrolithotomy for upper urinary tract calculi patients with metabolic syndrome].
abstract: OBJECTIVE
  To investigate the efficacy and safety of percutaneous nephrolithotomy (PCNL) for upper urinary tract calculi patients complicated with metabolic syndrome (MS).
  
  
  METHODS
  The clinical data of 66 PCNL cases with upper urinary tract calculi from March 2010 to February 2011 were retrospectively reviewed. Patients were divided into two groups according to 2004 Diagnostic Criteria of Metabolic Syndrome by the Chinese Diabetes Society (CDS). Twenty six upper urinary tract calculi patients complicated with metabolic syndrome were defined as case group (average aged 52.4 years, 16 males and 10 females). The other 40 cases without MS served as control group (average aged 45.9 years, 21 males and 19 females). The stone burden was (7.2 ± 1.8) cm(3) in case group and (6.4 ± 1.3) cm(3) in control group (P=0.712). The stone free rate, operative time, drop in hemoglobin level and fever were compared between the two groups.
  
  
  RESULTS
  The operation time was (87.1 ± 9.0) min in case group and (87.6 ± 6.0) min in control group (P=0.963). The stone free rate was 76.9% (20/26) vs. 75.0% (30/40), P=0.859. The drop in hemoglobin level was (8.4 ± 1.6) g/L vs. (9.1 ± 1.4) g/L, P=0.739. The incidence of post-operative fever was 38.5% (10/26) vs. 45.0% (18/40), P=0.599.
  
  
  CONCLUSIONS
  MS will neither increase the difficulty of surgery, nor reduce the stone free rate of PCNL for upper urinary tract calculi. And it will not raise the incidence of postoperative complications.
authors.affiliation: Department of Urology, Peking University People's Hospital, Beijing 100044, China.
authors.forename: Tian
authors.initials: T
authors.lastname: Wang
authors.forename: Xiao-bo
authors.initials: XB
authors.lastname: Huang
authors.forename: Qing-quan
authors.initials: QQ
authors.lastname: Xu
authors.forename: Hai-yun
authors.initials: HY
authors.lastname: Ye
authors.forename: Kai
authors.initials: K
authors.lastname: Ma
authors.forename: Xiao-feng
authors.initials: XF
authors.lastname: Wang
mesh_terms: D005260:Female; D006801:Humans; D008096:Lithotripsy / Q000009:adverse effects* / Q000379:methods; D008297:Male; D024821:Metabolic Syndrome / Q000150:complications*; D008875:Middle Aged; D009403:Nephrostomy, Percutaneous / Q000009:adverse effects*; D012189:Retrospective Studies; D012449:Safety; D014514:Ureteral Calculi / Q000150:complications* / Q000628:therapy*