title: Management of corneal endothelial decompensation caused by iris-fixated phakic intraocular lenses with descemet stripping automated endothelial keratoplasty.
abstract: OBJECTIVE
  To describe 2 cases of corneal decompensation after iris-fixated phakic intraocular lens (pIOL) implantation requiring Descemet stripping automated endothelial keratoplasty (DSAEK).
  
  
  METHODS
  Case reports and literature review.
  
  
  RESULTS
  Two cases of corneal decompensation after pIOL implantation are reported. The average age at presentation was 52 years (range: 37 to 67 years) in 2 women. The mean presentation time of corneal decompensation after pIOL implantation was 29 months (range: 22 to 36 months). Both the affected eyes required pIOL explantation and DSAEK to treat corneal decompensation. One patient (1 eye) had concurrent cataract surgery to maximize visual rehabilitation. The mean follow-up after DSAEK surgery was 14 months (range: 12 to 16 months). The best-corrected visual acuity was 20/50 (range: 20/40 to 20/60) at the last follow-up.
  
  
  CONCLUSIONS
  Despite a good safety profile for iris-fixated pIOLs, some patients may still develop corneal decompensation after implantation. We report a pair of cases with corneal decompensation severe enough to warrant endothelial transplantation and pIOL explantation, with and without concomitant cataract surgery.
authors.affiliation: Wilmer Eye Institute, Johns Hopkins University, Baltimore, MD, USA.
authors.forename: Shameema
authors.initials: S
authors.lastname: Sikder
authors.forename: Virag
authors.initials: V
authors.lastname: Patel
authors.forename: Huck A
authors.initials: HA
authors.lastname: Holz
authors.forename: Mark D
authors.initials: MD
authors.lastname: Mifflin
authors.forename: Scott
authors.initials: S
authors.lastname: Davis
authors.forename: Majid
authors.initials: M
authors.lastname: Moshirfar
mesh_terms: D000328:Adult; D000368:Aged; D015715:Corneal Edema / Q000209:etiology / Q000601:surgery*; D057111:Descemet Stripping Endothelial Keratoplasty; D004728:Endothelium, Corneal / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D007498:Iris / Q000601:surgery*; D019654:Lens Implantation, Intraocular / Q000379:methods; D009216:Myopia / Q000601:surgery; D054120:Phakic Intraocular Lenses / Q000009:adverse effects*; D014792:Visual Acuity / Q000502:physiology