title: [Cardiac biomarkers in perioperative medicine : significance for noncardiac surgery patients].
abstract: Perioperative detection of cardiac biomarkers may help to identify patients at risk. Whether detection of these markers will be recommended in the preoperative setting for patients with cardiac diseases in the future has to be discussed as large prospective trials on this topic are missing. For preoperative evaluation of cardiac insufficiency quantification of brain natriuretic peptide (BNP) and amino-terminal pro-brain natriuretic peptide (NT-proBNP) are useful markers. Troponin is the marker of choice for detection of myocardial ischemia/infarction in the postoperative setting. In unstable patients coronary angiography and/or percutaneous coronary intervention (PCI) are indicated. However, in stable patients the decision for coronary angiography and/or PCI has to be made in each patient individually after interdisciplinary discussion between anesthesiologists, cardiologists and surgeons.
authors.affiliation: Klinik und Poliklinik für Innere Medizin III, Universitätsklinikum, Martin Luther-Universität Halle-Wittenberg, Halle (Saale), Deutschland. axel.schlitt@medizin.uni-halle.de
authors.forename: A
authors.initials: A
authors.lastname: Schlitt
authors.forename: I
authors.initials: I
authors.lastname: Reindl
authors.forename: H
authors.initials: H
authors.lastname: Ebelt
authors.forename: M
authors.initials: M
authors.lastname: Buerke
authors.forename: K
authors.initials: K
authors.lastname: Werdan
mesh_terms: D015415:Biomarkers; D002097:C-Reactive Protein / Q000032:analysis; D017023:Coronary Angiography; D006321:Heart / Q000502:physiology*; D006334:Heart Function Tests; D006801:Humans; D009203:Myocardial Infarction / Q000097:blood / Q000175:diagnosis; D017202:Myocardial Ischemia / Q000097:blood / Q000175:diagnosis; D020097:Natriuretic Peptide, Brain / Q000097:blood; D010446:Peptide Fragments / Q000097:blood; D019990:Perioperative Care; D018570:Risk Assessment; D013514:Surgical Procedures, Operative; D014336:Troponin / Q000097:blood
chemical_list: D015415:Biomarkers; D010446:Peptide Fragments; D014336:Troponin; C109794:pro-brain natriuretic peptide (1-76); D020097:Natriuretic Peptide, Brain; D002097:C-Reactive Protein