title: Differentiation of intercalated cells in the kidney.
abstract: The intercalated cell of collecting ducts of the kidney is of two forms, the α form secretes acid, whereas the β form secretes HCO(3). Here, we review recent work that shows that the α form is derived from the β form and that the pathway is mediated by an extracellular matrix protein called hensin/DMBT1.
authors.affiliation: Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, New York, USA. Qa1@columbia.edu
authors.forename: Qais
authors.initials: Q
authors.lastname: Al-Awqati
authors.forename: Xaio Bo
authors.initials: XB
authors.lastname: Gao
mesh_terms: D000818:Animals; D002454:Cell Differentiation / Q000502:physiology*; D016326:Extracellular Matrix Proteins / Q000378:metabolism; D006801:Humans; D007668:Kidney / Q000166:cytology* / Q000378:metabolism; D007685:Kidney Tubules, Collecting / Q000166:cytology / Q000378:metabolism
chemical_list: D016326:Extracellular Matrix Proteins