title: Performance of glycogen phosphorylase isoenzyme BB is weak in the detection of patients with non-ST-elevation acute coronary syndrome.
abstract: OBJECTIVE
  To examine the diagnostic performance of glycogen-phosphorylase-isoenzyme-BB (GPBB) combined with cardiac troponin I (cTnI) in acute coronary syndrome (ACS).
  
  
  METHODS
  Sixty patients with chest pain were investigated; GPBB and cTnI were measured.
  
  
  RESULTS
  ACS was confirmed in 31 patients; cTnI was >0.07 μg/L in 15 patients and GPBB was >10 μg/L in 6 patients. Areas under ROC curves were similar: 0.854 (cTnI+GPBB) vs. 0.843 (cTnI), p=0.728.
  
  
  CONCLUSIONS
  Combination of GPBB with cTnI does not improve the detection of ACS.
authors.affiliation: Cardiology Department, Université Paris Descartes, Groupe Hospitalier Cochin-Broca-Hôtel Dieu, APHP, Paris, France.
authors.forename: Christophe
authors.initials: C
authors.lastname: Meune
authors.forename: Karim
authors.initials: K
authors.lastname: Wahbi
authors.forename: Simon
authors.initials: S
authors.lastname: Weber
authors.forename: Stéphane
authors.initials: S
authors.lastname: Zuily
authors.forename: Luc
authors.initials: L
authors.lastname: Cynober
authors.forename: Camille
authors.initials: C
authors.lastname: Chenevier-Gobeaux
mesh_terms: D054058:Acute Coronary Syndrome / Q000097:blood* / Q000175:diagnosis / Q000201:enzymology*; D015415:Biomarkers / Q000097:blood; D002637:Chest Pain / Q000097:blood / Q000175:diagnosis; D005260:Female; D024981:Glycogen Phosphorylase / Q000097:blood*; D006801:Humans; D008297:Male; D008875:Middle Aged; D019210:Troponin I / Q000097:blood*
chemical_list: D015415:Biomarkers; D019210:Troponin I; D024981:Glycogen Phosphorylase; C528446:glycogen phosphorylase BB, human