title: P300 in neglect.
abstract: OBJECTIVE
  Attentional deficits have been thought to underlie hemispatial neglect. The present study investigates this using the P300 component of the event-related potential, which is assumed to reflect the allocation of attention.
  
  
  METHODS
  We recorded the P300 and oddball detection performance from patients with neglect. Infrequent targets appeared either in the affected contralesional or the unaffected ipsilesional visual hemifield.
  
  
  RESULTS
  Contralesional targets produced weaker average P300 responses than ipsilesional ones, but stronger responses than when only distractors were presented. In the affected hemifield, the difference in P300 amplitude between identified and missed targets was correlated with the miss rate. The number of missed contralesional targets for a given participant was positively correlated with the time required for completion of standard neglect tests.
  
  
  CONCLUSIONS
  The P300 not only reflects a general attentional impairment in neglect, but also varies as a function of the participants' awareness of individual stimuli.
  
  
  CONCLUSIONS
  The findings reflect an important link between attentional dysfunction and impaired stimulus processing in neglect and extinction.
authors.affiliation: Department of Neuropsychology, Institute of Psychology, University of Freiburg, Engelbergstr. 41, 79085 Freiburg, Germany. a.a.wijers@rug.nl
authors.forename: Styrmir
authors.initials: S
authors.lastname: Saevarsson
authors.forename: Arni
authors.initials: A
authors.lastname: Kristjánsson
authors.forename: Michael
authors.initials: M
authors.lastname: Bach
authors.forename: Sven P
authors.initials: SP
authors.lastname: Heinrich
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001288:Attention / Q000502:physiology; D001289:Attention Deficit Disorder with Hyperactivity / Q000175:diagnosis / Q000503:physiopathology*; D004569:Electroencephalography; D018913:Event-Related Potentials, P300 / Q000502:physiology*; D005108:Extinction, Psychological / Q000502:physiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010468:Perceptual Disorders / Q000175:diagnosis / Q000503:physiopathology*; D010775:Photic Stimulation; D014796:Visual Perception