title: Target weight gain for moderately wasted children during supplementation interventions--a population-based approach.
abstract: OBJECTIVE
  In malnourished populations, the weight-for-height Z-score (WHZ) distribution is shifted to the left. The aim of nutrition interventions should be to restore a normal WHZ distribution for the whole population. The present paper examines the WHZ change needed by each individual to achieve this objective.
  
  
  METHODS
  We developed a mathematical model of required individual change in WHZ as a function of characteristics of the initial population to restore a normal distribution. This model was then tested by simulating WHZ change needed to restore a normal WHZ distribution in a test population.
  
  
  METHODS
  A rural area of Democratic Republic of the Congo with a high prevalence of undernutrition.
  
  
  METHODS
  Children under 5 years of age.
  
  
  RESULTS
  To restore a normal distribution for the whole population, the WHZ of all children should be shifted. The desired WHZ change of each individual should be higher when the individual's initial WHZ is low, when the mean WHZ of the whole population is low and, for the most wasted individual, when the variance of WHZ and WHZ change in the population are high. Using the suggested model in a simulation on the test population resulted in a WHZ distribution close to the growth standard.
  
  
  CONCLUSIONS
  To restore a normal WHZ distribution in wasted populations, nutritional programmes should cover the whole population with a higher weight gain in areas where mean WHZ is low.
authors.affiliation: Department of International Health, University of Tampere Medical School, FIN-33014, Tampere, Finland. andre.briend@gmail.com
authors.forename: André
authors.initials: A
authors.lastname: Briend
authors.forename: Jan
authors.initials: J
authors.lastname: Van den Broeck
authors.forename: Lars T
authors.initials: LT
authors.lastname: Fadnes
mesh_terms: D001827:Body Height; D002675:Child, Preschool; D015023:Democratic Republic of the Congo / Q000453:epidemiology; D019587:Dietary Supplements; D004614:Emaciation / Q000453:epidemiology* / Q000517:prevention & control; D006801:Humans; D044342:Malnutrition / Q000453:epidemiology* / Q000517:prevention & control; D008962:Models, Theoretical; D009752:Nutritional Status; D015995:Prevalence; D015430:Weight Gain