title: Methicillin-susceptible Staphylococcus aureus nasal colonization and the risk of subsequent methicillin-resistant Staphylococcus aureus infections among hospitalized patients.
abstract: Few data exist on the risk of methicillin-resistant Staphylococcus aureus (MRSA) infections among known methicillin-susceptible S. aureus (MSSA) carriers. In a cohort of 2991 hospitalized MSSA carriers, 22 (22%) of 98 S. aureus infections that occurred within a subsequent 6-month period were caused by MRSA. Recent fluoroquinolone use was an independent predictor of MRSA infections (P < .001).
authors.affiliation: Department of Medicine, Beth Israel Medical Center, New York, NY 10003, USA. jruhe@chpnet.org
authors.forename: Jörg J
authors.initials: JJ
authors.lastname: Ruhe
authors.forename: Leonidez
authors.initials: L
authors.lastname: de Guzman
authors.forename: Marie
authors.initials: M
authors.lastname: Moss
authors.forename: William
authors.initials: W
authors.lastname: Riley
authors.forename: Donna
authors.initials: D
authors.lastname: Mildvan
authors.forename: David C
authors.initials: DC
authors.lastname: Perlman
authors.forename: Brian
authors.initials: B
authors.lastname: Koll
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002353:Carrier State / Q000453:epidemiology / Q000382:microbiology; D003428:Cross Infection / Q000453:epidemiology* / Q000382:microbiology; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D055624:Methicillin-Resistant Staphylococcus aureus / Q000302:isolation & purification* / Q000472:pathogenicity*; D008875:Middle Aged; D015999:Multivariate Analysis; D009296:Nasal Cavity / Q000382:microbiology / Q000473:pathology; D016017:Odds Ratio; D012189:Retrospective Studies; D012307:Risk Factors; D013203:Staphylococcal Infections / Q000453:epidemiology* / Q000382:microbiology*; D055815:Young Adult