title: Complex mammary adenoma with sebaceous differentiation in a dog.
abstract: Sebaceous metaplasia arising within a complex adenoma of the left fourth mammary gland is described in a 9-year-old miniature pinscher bitch. Microscopically, the tumour was composed of tubular and ductular structures admixed with clusters of spindle-shaped, myoepithelial-like cells and units formed of well-differentiated sebocytes surrounded by basaloid cells. Abundant lipid droplets were identified within the latter population by Sudan III staining. Immunohistochemical expression of cytokeratin AE1/AE3 was detected in epithelial cells and in the cells with sebaceous differentiation.
authors.affiliation: Department of Veterinary Pathology, Faculty of Veterinary Medicine, University of Zagreb, Heinzelova 55, Zagreb 10000, Croatia. agudan@vef.hr
authors.forename: A G
authors.initials: AG
authors.lastname: Kurilj
authors.forename: M
authors.initials: M
authors.lastname: Hohšteter
authors.forename: A
authors.initials: A
authors.lastname: Beck
authors.forename: B
authors.initials: B
authors.lastname: Artuković
authors.forename: I-C
authors.initials: IC
authors.lastname: Soštarić-Zuckermann
authors.forename: Z
authors.initials: Z
authors.lastname: Grabarević
mesh_terms: D000236:Adenoma / Q000473:pathology / Q000662:veterinary*; D000818:Animals; D002454:Cell Differentiation; D004283:Dog Diseases / Q000473:pathology*; D004285:Dogs; D004847:Epithelial Cells / Q000473:pathology; D005260:Female; D015674:Mammary Neoplasms, Animal / Q000473:pathology*