title: Clinical features and surgical outcome of solid pseudopapillary tumor of the pancreas: 30 consecutive clinical cases.
abstract: OBJECTIVE
  This study examined the clinical characteristics and surgical outcomes of solid pseudopapillary tumors of the pancreas (SPT).
  
  
  METHODS
  Cases of SPT encountered in our hospital between January 1994 and December 2009 were reviewed retrospectively. The clinicopathological factors in the benign and malignant cases were compared to determine what features of the tumor could suggest malignant potential.
  
  
  RESULTS
  Thirty patients with SPT were identified: 26 females and 4 males with a average age of 30.5 years (range 9-66). The median size of the tumors was 6.2cm (range 1.25 to 15.0). Tumors were located in the head (50%), neck (3.3%), body (16.7%) and tail (30%) of the pancreas. Surgical procedures included a local tumor resection (10 cases) or radical resection, such as a pancreaticoduodenectomy (6 cases), central pancreatectomy (1 case) or distal pancreatectomy (13 cases). There was no recurrence after the surgical resection. All patients were alive at a median follow-up of 58 months (range 6 to 187). Among the clinico-pathological factors, the presence of calcification was associated with the malignant potential (OR=16.000, 95% CI=1.451-176.451, p=0.024).
  
  
  CONCLUSIONS
  SPT is a less aggressive pancreatic neoplasm that differs from other pancreatic cancers. The prognosis is favorable after a surgical resection. The presence of calcification is a predictive factor for a malignant SPT.
authors.affiliation: Department of Surgery, Chonnam National University Medical School, Gwangju, Korea.
authors.forename: Ho Hyun
authors.initials: HH
authors.lastname: Kim
authors.forename: Sang Kwon
authors.initials: SK
authors.lastname: Yun
authors.forename: Jung Chul
authors.initials: JC
authors.lastname: Kim
authors.forename: Eun Kyu
authors.initials: EK
authors.lastname: Park
authors.forename: Jin Shick
authors.initials: JS
authors.lastname: Seoung
authors.forename: Young Hoe
authors.initials: YH
authors.lastname: Hur
authors.forename: Yang Seok
authors.initials: YS
authors.lastname: Koh
authors.forename: Chol Kyoon
authors.initials: CK
authors.lastname: Cho
authors.forename: Sang Soo
authors.initials: SS
authors.lastname: Shin
authors.forename: Sun Seog
authors.initials: SS
authors.lastname: Kweon
authors.forename: Hyung Seok
authors.initials: HS
authors.lastname: Kim
authors.forename: Hyun Jong
authors.initials: HJ
authors.lastname: Kim
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002291:Carcinoma, Papillary / Q000473:pathology / Q000601:surgery*; D002648:Child; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010190:Pancreatic Neoplasms / Q000473:pathology / Q000601:surgery*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome