title: Liver cirrhosis as a delayed complication of Stevens-Johnson syndrome.
abstract: A 26-year-old woman was referred to our department due to fever and skin rash after having taken medication for a common cold. Physical examination revealed erythematous skin changes on her body associated with mucosal involvement in her eyes and oral cavity. Peripheral blood examination revealed leukopenia and thrombocytopenia. Liver function test showed hyperbilirubinemia. She was managed with high dose intravenous immunoglobulin (IVIG) at 1.0 gm/kg of body weight infused for 5 consecutive days. Although the patient's skin lesion improved dramatically with IVIG therapy, her hyperbilirubinemia aggravated progressively. Eighteen months after her presentation, liver cirrhosis was diagnosed by ultrasonography, laboratory and liver biopsy findings.
authors.affiliation: Department of Internal Medicine, College of Medicine, Dong-A University, Republic of Korea.
authors.forename: Young-Hee
authors.initials: YH
authors.lastname: Nam
authors.forename: Sung-Wook
authors.initials: SW
authors.lastname: Lee
authors.forename: Soo-Keol
authors.initials: SK
authors.lastname: Lee
authors.forename: Mee-Sook
authors.initials: MS
authors.lastname: Roh
authors.forename: Il-Hwan
authors.initials: IH
authors.lastname: Jeong
authors.forename: Su-Min
authors.initials: SM
authors.lastname: Park
authors.forename: Neul-Bom
authors.initials: NB
authors.lastname: Yoon
authors.forename: Ki-Ho
authors.initials: KH
authors.lastname: Kim
authors.forename: Soo-Jung
authors.initials: SJ
authors.lastname: Um
authors.forename: Choon-Hee
authors.initials: CH
authors.lastname: Son
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000008:administration & dosage; D008103:Liver Cirrhosis / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology*; D013262:Stevens-Johnson Syndrome / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy
chemical_list: D016756:Immunoglobulins, Intravenous