title: Delaying vascular aging with Chinese medicine: implications from an overview of the p53 and miR-34s family.
abstract: p53 is an important target for studying vascular aging. However, as people gradually learned more about the miR-34s and the relationship between miR-34s and p53, new research idea emerged. This paper tries to elaborate the feature of p53, microRNA and miR-34s in-depth, analyze the regulatory action of miR-34s on p53, and offer some new prevention and treatment prospects about vascular aging in Chinese medicine.
authors.affiliation: Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
authors.forename: Ming
authors.initials: M
authors.lastname: Wang
authors.forename: Yan
authors.initials: Y
authors.lastname: Lei
mesh_terms: D001808:Blood Vessels / Q000473:pathology*; D016922:Cellular Senescence; D025461:Feedback, Physiological; D006801:Humans; D008516:Medicine, Chinese Traditional; D035683:MicroRNAs / Q000378:metabolism*; D016159:Tumor Suppressor Protein p53 / Q000378:metabolism*
chemical_list: D035683:MicroRNAs; D016159:Tumor Suppressor Protein p53