title: Predicting successful 24-hr quit attempt in a smoking cessation intervention.
abstract: BACKGROUND
  The factors that influence the initial phase of quitting smoking have been understudied. Although maintenance of change is the ultimate test of the efficacy of treatment, maintenance is a nonissue for those who fail to manage even brief periods of abstinence. We examined factors associated with smokers' ability to achieve a targeted 24-hr quit during a smoking cessation program. As a comparison, we also examine whether predictors of an initial quit are different from factors that predict smoking abstinence at 52-week follow-up.
  
  
  METHODS
  Using baseline data from a randomized clinical trial to examine the efficacy of selegiline for cigarette smoking cessation (n = 280), we conducted univariate analyses (analysis of variance or chi-square) to determine statistically significant predictors of a successful quit attempt (SQA) versus unsuccessful quit attempt. Multiple logistic regression was performed with significant predictors from the univariate analyses to determine main effects and interactions in a multivariate model. The same factors and analyses were used to examine predictors of 52-week point prevalence abstinence.
  
  
  RESULTS
  Lower nicotine dependence (modified Fagerström Tolerance Questionnaire [mFTQ]), higher Behavioral Inhibition System score, and lower baseline heart rate were predictive of SQA in both the univariate and the multivariate models. Gender was the only predictor of 52-week smoking abstinence.
  
  
  CONCLUSIONS
  Predictors of initial induction of change were not predictors of abstinence at the 1-year follow-up, suggesting that different factors mediate the different subprocesses of behavior change. Knowledge of these pretreatment factors that moderate a SQA could help clinicians target smokers who need more intensive therapy during the initial induction of cessation.
authors.affiliation: Stanford Prevention Research Center, Stanford University School of Medicine, 1070 Arastradero Road, Suite 300, Palo Alto, CA 94304-1334, USA. stbailey@stanford.edu
authors.forename: Steffani R
authors.initials: SR
authors.lastname: Bailey
authors.forename: Susan W
authors.initials: SW
authors.lastname: Bryson
authors.forename: Joel D
authors.initials: JD
authors.lastname: Killen
mesh_terms: D000328:Adult; D001521:Behavior Therapy; D004311:Double-Blind Method; D005260:Female; D005500:Follow-Up Studies; D006293:Health Promotion; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D008996:Monoamine Oxidase Inhibitors / Q000627:therapeutic use*; D012642:Selegiline / Q000627:therapeutic use*; D057566:Self Report; D012737:Sex Factors; D016540:Smoking Cessation / Q000379:methods* / Q000706:statistics & numerical data; D000074606:Smoking Prevention; D013997:Time Factors; D014029:Tobacco Use Disorder / Q000628:therapy*; D057968:Transdermal Patch; D016896:Treatment Outcome
chemical_list: D008996:Monoamine Oxidase Inhibitors; D012642:Selegiline