title: Early pregnancy complicated with juvenile granulosa cell tumor.
abstract: BACKGROUND
  Granulosa cell tumors (GCTs) are extremely rare tumors and are divided into 2 types: adult (AGCT) and juvenile (JGCT). The JGCTs represent only 5% of all cases. The incidence of ovarian carcinoma diagnosed during pregnancy varies about 0.0179 to 0.11 per 1000 pregnancies.
  
  
  METHODS
  A 24-year-old woman at 12 weeks and 3 days of pregnancy was admitted to the authors' hospital due to a pelvic mass. Surgical exploration revealed a smooth, solid, mobile and well-encapsulated left ovarian mass. Histological and immunohistochemical findings led to the diagnosis of a well-differentiated JGCT. Pregnancy continued uncomplicated and she delivered a healthy baby girl at 37 weeks gestation. About 9 months after the original diagnosis, the patient showed no evidence of disease.
  
  
  CONCLUSIONS
  Treatment options and a review of the literature related to JGCTs are discussed.
authors.affiliation: First Hospital, Jilin University, Changchun 130021, China.
authors.forename: Hongmei
authors.initials: H
authors.lastname: Xu
authors.forename: Chang
authors.initials: C
authors.lastname: Shu
authors.forename: Na
authors.initials: N
authors.lastname: Li
authors.forename: Meihui
authors.initials: M
authors.lastname: Xia
authors.forename: Tingting
authors.initials: T
authors.lastname: Li
authors.forename: Yanping
authors.initials: Y
authors.lastname: Zhong
authors.forename: Xu
authors.initials: X
authors.lastname: Yan
authors.forename: Hong
authors.initials: H
authors.lastname: Wang
authors.forename: Haipeng
authors.initials: H
authors.lastname: Zhang
authors.forename: Jin
authors.initials: J
authors.lastname: He
mesh_terms: D000328:Adult; D005260:Female; D006106:Granulosa Cell Tumor / Q000473:pathology* / Q000601:surgery; D006801:Humans; D010051:Ovarian Neoplasms / Q000473:pathology* / Q000601:surgery; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000473:pathology* / Q000601:surgery; D016896:Treatment Outcome