title: How does morphology relate to function in sensory arbors?
abstract: Sensory dendrites fall into many different morphological and functional classes. Polymodal nociceptors are one subclass of sensory neurons, which are of particular note owing to their elaborate dendritic arbors. Complex developmental programs are required to form these arbors and there is striking conservation of morphology, function and molecular determinants between vertebrate and invertebrate polymodal nociceptors. Based on these studies, we argue that arbor morphology plays an important role in the function of polymodal nociceptors. Similar associations between form and function might explain the plethora of dendrite morphologies seen among all sensory neurons.
authors.affiliation: Department of Neuroscience, Albert Einstein College of Medicine, Bronx, New York 10461, USA.
authors.forename: David H
authors.initials: DH
authors.lastname: Hall
authors.forename: Millet
authors.initials: M
authors.lastname: Treinin
mesh_terms: D000818:Animals; D017173:Caenorhabditis elegans / Q000033:anatomy & histology / Q000254:growth & development; D048430:Cell Shape; D003712:Dendrites / Q000502:physiology* / Q000648:ultrastructure*; D004331:Drosophila melanogaster / Q000033:anatomy & histology / Q000254:growth & development; D008465:Mechanoreceptors / Q000502:physiology / Q000648:ultrastructure; D040542:Mechanotransduction, Cellular; D009619:Nociceptors / Q000502:physiology* / Q000648:ultrastructure*