title: Fetal gender ratio in recurrent miscarriages.
abstract: BACKGROUND
  The purpose of this study was to evaluate the gender ratio and incidence of chromosomal anomalies in the products of conception (POC) from recurrent miscarriages.
  
  
  METHODS
  We determined the karyotypes of POC from patients with recurrent spontaneous miscarriages between 1999 and 2009.
  
  
  RESULTS
  In total, 313 specimens were successfully karyotyped, with a median gestational age of 10 weeks at miscarriage (interquartile range 8-13); 199 (64%) were females and 114 (36%) were males. In total, 121 (39%) had abnormal karyotypes, the most prevalent of which were chromosome 21 and 16 trisomies, triploidy, and monosomy X.
  
  
  CONCLUSIONS
  Our findings suggest that female POC might be more susceptible to recurrent miscarriages than male ones during embryogenesis, implantation, and initial fetal development.
authors.affiliation: Clinic of Obstetrics and Gynecology.
authors.forename: Anna
authors.initials: A
authors.lastname: Del Fabro
authors.forename: Lorenza
authors.initials: L
authors.lastname: Driul
authors.forename: Omar
authors.initials: O
authors.lastname: Anis
authors.forename: Ambrogio P
authors.initials: AP
authors.lastname: Londero
authors.forename: Serena
authors.initials: S
authors.lastname: Bertozzi
authors.forename: Livio
authors.initials: L
authors.lastname: Bortotto
authors.forename: Diego
authors.initials: D
authors.lastname: Marchesoni