title: Comparative and stability analyses of 9- and 13-Oxo-octadecadienoic acids in various species of tomato.
abstract: Peroxisome proliferator-activated receptor-α (PPARα) regulates lipid metabolism. We have reported that tomato fruit contains 9-Oxo-(10E,12E)-octadecadienoic acid (9-Oxo-(10E,12E)-ODA), a PPARα agonist. In this study, we found that various tomato samples contained 9-Oxo-(10E,12Z)-ODA and its 13-Oxo-ODA isomers. Furthermore, several isomers showed structural stability under hot and acidic conditions.
authors.affiliation: Laboratory of Molecular Functions of Food, Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University, Uji, Kyoto, Japan.
authors.forename: Haruya
authors.initials: H
authors.lastname: Takahashi
authors.forename: Young-Il
authors.initials: YI
authors.lastname: Kim
authors.forename: Shizuka
authors.initials: S
authors.lastname: Hirai
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Goto
authors.forename: Chie
authors.initials: C
authors.lastname: Ohyane
authors.forename: Taneaki
authors.initials: T
authors.lastname: Tsugane
authors.forename: Chiaki
authors.initials: C
authors.lastname: Konishi
authors.forename: Takashi
authors.initials: T
authors.lastname: Fujii
authors.forename: Shuji
authors.initials: S
authors.lastname: Inai
authors.forename: Yoko
authors.initials: Y
authors.lastname: Iijima
authors.forename: Koh
authors.initials: K
authors.lastname: Aoki
authors.forename: Daisuke
authors.initials: D
authors.lastname: Shibata
authors.forename: Nobuyuki
authors.initials: N
authors.lastname: Takahashi
authors.forename: Teruo
authors.initials: T
authors.lastname: Kawada
mesh_terms: D002853:Chromatography, Liquid; D004355:Drug Stability; D050171:Dyslipidemias / Q000188:drug therapy / Q000503:physiopathology; D005231:Fatty Acids, Unsaturated / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D005638:Fruit / Q000737:chemistry*; D007536:Isomerism; D050356:Lipid Metabolism / Q000187:drug effects*; D018551:Solanum lycopersicum / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D047493:PPAR alpha / Q000819:agonists* / Q000378:metabolism
chemical_list: D005231:Fatty Acids, Unsaturated; D047493:PPAR alpha; C027369:octadecadienoic acid