title: Toxic multinodular goiter with low radioactive iodine uptake.
abstract: A 74-year-old woman was referred to our hospital for goiter and persistent thyrotoxicosis. She had no signs of ophthalmopathy. She was not taking thyroid hormone. Thyroid CT revealed multiple nodules. The thyroid gland was not detected on (99m)Tc scintigraphy, (123)I uptake rate was 4.5% at 24 hours without hot nodules, and aberrant goiter was negative. After partial thyroidectomy, she was treated with levothyroxine. TRAb was undetectable during the disease course, and focal destructive change or chronic lymphocytic thyroiditis on the pathological specimens was not evident. We report a rare case of toxic multinodular goiter with low radioactive iodine uptake.
authors.affiliation: Department of Internal Medicine, Toyama Prefectural Central Hospital, Japan. kchizu1230@yahoo.co.jp
authors.forename: Toshio
authors.initials: T
authors.lastname: Kahara
authors.forename: Akiko
authors.initials: A
authors.lastname: Shimizu
authors.forename: Akio
authors.initials: A
authors.lastname: Uchiyama
authors.forename: Shintaro
authors.initials: S
authors.lastname: Terahata
authors.forename: Junichi
authors.initials: J
authors.lastname: Tajiri
authors.forename: Eijun
authors.initials: E
authors.lastname: Nishihara
authors.forename: Akira
authors.initials: A
authors.lastname: Miyauchi
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Abo
authors.forename: Hisashi
authors.initials: H
authors.lastname: Sumiya
authors.forename: Kazuhide
authors.initials: K
authors.lastname: Ishikura
authors.forename: Rika
authors.initials: R
authors.lastname: Usuda
authors.forename: Hirofumi
authors.initials: H
authors.lastname: Noto
mesh_terms: D000368:Aged; D005260:Female; D006044:Goiter, Nodular / Q000175:diagnosis* / Q000378:metabolism* / Q000601:surgery; D006801:Humans; D007457:Iodine Radioisotopes / Q000378:metabolism*; D013971:Thyrotoxicosis / Q000175:diagnosis / Q000378:metabolism / Q000601:surgery
chemical_list: D007457:Iodine Radioisotopes