title: [Clinical analysis of 35 cases of penile cancer].
abstract: We retrospectively reviewed the records of 35 patients with penile cancer, who had been treated at Gifu University Hospital and its affiliated hospitals between July 1994 and January 2009. The mean values of follow-up periods, ages, serum squamous cell carcinoma levels and maximum diameters of the tumor were 23.7±28.0 months, 72.3±10.5 year-old, 4.5±4.3 ng/ml, and 4.0±2.6 cm, respectively. Systemic chemotherapy and local radiotherapy were performed in six, and three cases, respectively. Ten patients died of penile cancer. By univariate analyses, maximum tumor diameter (＜- 4.3 cmvs ＞4.3 cm), T factor (＜T3 vs ＞- T3) and N factor (＜N2 vs ＞- N2) were significantly associated with cancer-specific survival. The five-year survival of stage N2 cases (28.6%) were significantly lower than that of stage N0 and N1 cases (68.4%) (p＝0.0003). By multivariate analyses N factor (＜N2 vs ＞- N2) was significantly associated with cancer specific survival (p＝0.020). We concluded that the development of effective systemic chemotherapy might be crucial to improve the prognosis of patients with metastatic diseases.
authors.affiliation: The Department of Urology, Gifu University Graduate School of Medicine.
authors.forename: Taku
authors.initials: T
authors.lastname: Kato
authors.forename: Hidetoshi
authors.initials: H
authors.lastname: Ehara
authors.forename: Kimiaki
authors.initials: K
authors.lastname: Takagi
authors.forename: Kengo
authors.initials: K
authors.lastname: Horie
authors.forename: Shinichi
authors.initials: S
authors.lastname: Hattori
authors.forename: Keita
authors.initials: K
authors.lastname: Nakane
authors.forename: Kensaku
authors.initials: K
authors.lastname: Seike
authors.forename: Takashi
authors.initials: T
authors.lastname: Sugawara
authors.forename: Takahiro
authors.initials: T
authors.lastname: Goto
authors.forename: Naruyasu
authors.initials: N
authors.lastname: Masue
authors.forename: Masayoshi
authors.initials: M
authors.lastname: Tamaki
authors.forename: Yasuhisa
authors.initials: Y
authors.lastname: Ito
authors.forename: Takashi
authors.initials: T
authors.lastname: Deguchi
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D006801:Humans; D008297:Male; D008875:Middle Aged; D010412:Penile Neoplasms / Q000401:mortality* / Q000473:pathology / Q000628:therapy; D011379:Prognosis; D012189:Retrospective Studies; D015996:Survival Rate