title: Osteolipoma: radiological, pathological, and cytogenetic analysis of three cases.
abstract: Osteolipoma is a rare variant of lipoma consisting of mature adipose tissue and mature lamellar bone. The presence of non-fatty elements may lead to a wide differential diagnosis on radiology including benign and malignant lipomatous and nonlipomatous entities. The pathological diagnosis is also confounded by the presence of heterologous differentiation. Fortunately, most lipomas harbor classic cytogenetic aberrations, and the finding of translocations involving 12q13-15 may aid in the correct diagnosis. We report three cases of osteolipoma with radiological, histological, and cytogenetic correlation.
authors.affiliation: Department of Laboratory Medicine and Pathology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA. karenfritchie@gmail.com
authors.forename: Karen J
authors.initials: KJ
authors.lastname: Fritchie
authors.forename: Jordan B
authors.initials: JB
authors.lastname: Renner
authors.forename: Kathleen W
authors.initials: KW
authors.lastname: Rao
authors.forename: Robert J
authors.initials: RJ
authors.lastname: Esther
mesh_terms: D000328:Adult; D001859:Bone Neoplasms / Q000175:diagnosis*; D005260:Female; D020022:Genetic Predisposition to Disease / Q000235:genetics; D006801:Humans; D008067:Lipoma / Q000175:diagnosis* / Q000235:genetics*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed / Q000379:methods*