title: Comparisons of inhibin B versus antimüllerian hormone in poor ovarian responders undergoing in vitro fertilization.
abstract: OBJECTIVE
  To evaluate serum inhibin B as a predictor of poor ovarian response in patients undergoing in vitro fertilization/intracytoplasmic sperm injection (IVF-ICSI) and to compare it with the performance of antimüllerian hormone (AMH).
  
  
  METHODS
  Meta-analysis.
  
  
  METHODS
  University hospital.
  
  
  METHODS
  Patients undergoing IVF.
  
  
  METHODS
  None.
  
  
  METHODS
  Poor ovarian response in controlled ovarian hyperstimulation (COH).
  
  
  RESULTS
  Fifteen studies on serum inhibin B and 12 studies on AMH were selected for meta-analysis. Both basal and stimulated inhibin B levels were statistically significantly lower in poor ovarian responders than in controls. The estimated summary receiver operating characteristic (ROC) curves suggested that stimulated inhibin B was more accurate than basal inhibin B and AMH in the prediction of poor ovarian response.
  
  
  CONCLUSIONS
  Both basal and stimulated serum inhibin B levels are lower in poor responders than in controls. Compared with AMH, stimulated inhibin B is a more accurate predictor of ovarian response in patients undergoing IVF, making it a potentially useful tool in future IVF practice.
authors.affiliation: The State Key Laboratory of Reproductive Medicine, Department of Obstetrics and Gynecology, The First Affiliated Hospital of Nanjing Medical University, Nanjing Medical University, Nanjing, People's Republic of China.
authors.forename: Rongrong
authors.initials: R
authors.lastname: Tan
authors.forename: Danhua
authors.initials: D
authors.lastname: Pu
authors.forename: Lipeng
authors.initials: L
authors.lastname: Liu
authors.forename: Jiayin
authors.initials: J
authors.lastname: Liu
authors.forename: Jie
authors.initials: J
authors.lastname: Wu
mesh_terms: D054304:Anti-Mullerian Hormone / Q000097:blood*; D015415:Biomarkers / Q000097:blood; D005260:Female; D005307:Fertilization in Vitro / Q000639:trends*; D006801:Humans; D007265:Inhibins / Q000097:blood*; D016471:Ovarian Hyperstimulation Syndrome / Q000097:blood*; D010062:Ovulation Induction / Q000639:trends*; D011237:Predictive Value of Tests; D020554:Sperm Injections, Intracytoplasmic / Q000639:trends; D016896:Treatment Outcome
chemical_list: D015415:Biomarkers; C422364:inhibin B; D007265:Inhibins; D054304:Anti-Mullerian Hormone