title: [Ultrastructural changes of the capillary endotheliocytes in the muscle tissue of patients with chronic ischemia of the extremities after transplantation of the progenitor fetal liver cells].
abstract: Taking into account impossibility of reconstruction-restoration operations performance in cases of the distal arterial bed affection, it is necessary to find out and elaborate the methods of indirect revascularization. The cells transplantation performance for stimulation of reparation and angiogenesis in the affected extremity is considered a perspective direction of treatment. Essential stimulation of angiogenesis occurs after transplantation of progenitor stem cells of a fetal liver according to the data, obtained in experiment on laboratory animals. Later, transplantation of the cells was accomplished in patients with chronic ischemia of the extremities. Using method of electron microscopy of endotheliocvtes of the muscular tissue capillaries there was proved, that the cells transplantation causes essential stimulation of angiogenesis in patients, suffering chronic ischemia and constitutes a perspective method of indirect revascularization.
authors.forename: Iu V
authors.initials: IuV
authors.lastname: Poliachenko
authors.forename: R V
authors.initials: RV
authors.lastname: Saliutin
mesh_terms: D000792:Angiography; D001162:Arteriosclerosis Obliterans / Q000473:pathology / Q000601:surgery; D002196:Capillaries / Q000648:ultrastructure*; D002908:Chronic Disease; D042783:Endothelial Cells / Q000648:ultrastructure*; D006801:Humans; D007511:Ischemia / Q000473:pathology / Q000601:surgery*; D007866:Leg / Q000098:blood supply*; D008099:Liver / Q000166:cytology* / Q000196:embryology; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D018482:Muscle, Skeletal / Q000098:blood supply*; D018919:Neovascularization, Physiologic; D033581:Stem Cell Transplantation; D018608:Ultrasonography, Doppler