title: Aspergillus fumigatus in Poultry.
abstract: Aspergillus fumigatus remains a major respiratory pathogen in birds. In poultry, infection by A. fumigatus may induce significant economic losses particularly in turkey production. A. fumigatus develops and sporulates easily in poor quality bedding or contaminated feedstuffs in indoor farm environments. Inadequate ventilation and dusty conditions increase the risk of bird exposure to aerosolized spores. Acute cases are seen in young animals following inhalation of spores, causing high morbidity and mortality. The chronic form affects older birds and looks more sporadic. The respiratory tract is the primary site of A. fumigatus development leading to severe respiratory distress and associated granulomatous airsacculitis and pneumonia. Treatments for infected poultry are nonexistent; therefore, prevention is the only way to protect poultry. Development of avian models of aspergillosis may improve our understanding of its pathogenesis, which remains poorly understood.
authors.affiliation: UMR BIPAR, Ecopham, Ecole Nationale Vétérinaire d'Alfort (ENVA), 94700 Maisons-Alfort, France.
authors.forename: Pascal
authors.initials: P
authors.lastname: Arné
authors.forename: Simon
authors.initials: S
authors.lastname: Thierry
authors.forename: Dongying
authors.initials: D
authors.lastname: Wang
authors.forename: Manjula
authors.initials: M
authors.lastname: Deville
authors.forename: Guillaume
authors.initials: G
authors.lastname: Le Loc'h
authors.forename: Anaïs
authors.initials: A
authors.lastname: Desoutter
authors.forename: Françoise
authors.initials: F
authors.lastname: Féménia
authors.forename: Adélaïde
authors.initials: A
authors.lastname: Nieguitsila
authors.forename: Weiyi
authors.initials: W
authors.lastname: Huang
authors.forename: René
authors.initials: R
authors.lastname: Chermette
authors.forename: Jacques
authors.initials: J
authors.lastname: Guillot