title: [Oocyte/embryo cryopreservation before chemotherapy for breast cancer].
abstract: Breast cancer affects 6300 new patients per year under age 40 per year in France. The new adjuvant chemotherapy protocols have significantly improved the prognosis of these young women who may wish to conceive later. Embryo cryopreservation is the best way to preserve fertility, providing 25 to 35% chance of pregnancy. Oocyte freezing may be an alternative for single patients. This review will focus on: (1) ovarian toxicity of new adjuvant chemotherapy protocols, (2) the place of embryo or oocyte cryopreservation in fertility preservation techniques, (3) indications and protocols.
authors.affiliation: Service d'AMP de l'hôpital Jeanne-de-Flandre, centre de préservation ovarienne, CHRU de Lille, rue Eugène-Avinée, Lille cedex, France. christine.decanter@chru-lille.fr
authors.forename: C
authors.initials: C
authors.lastname: Decanter
authors.forename: J
authors.initials: J
authors.lastname: Gligorov
mesh_terms: D000328:Adult; D001943:Breast Neoplasms / Q000188:drug therapy*; D017024:Chemotherapy, Adjuvant / Q000009:adverse effects; D015925:Cryopreservation; D004622:Embryo, Mammalian; D005260:Female; D059247:Fertility Preservation / Q000379:methods*; D005602:France; D006801:Humans; D007247:Infertility, Female / Q000139:chemically induced; D009865:Oocytes; D011247:Pregnancy