title: Purine scaffold effect on fluorescence properties of purine-hydroxyquinolinone bisheterocycles.
abstract: The fluorescence properties of bisheterocyclic compounds that contain purine and the 3-hydroxyquinolin-4(1H)-one skeleton connected with an aliphatic spacer of a different length/structure (3HQP) were examined. It was found that the introducing of the spacer-purine scaffold led in the comparison to 3HQs themselves to (1) the possibility of the effectual excitation in the wider range of excitation wavelengths, moreover, some derivatives can be excited at relatively high wavelengths around 400 nm, (2) the lowering of the quantum yield and (3) the slight longer wavelength shift of the dual emission spectra. Tested organic solvents did not affect significantly the 3HQP fluorescence properties. The characters of emission spectra as well as the quantum yields of 3HQPs were notably influenced by the ratio of water and DMSO in their composed mixture applied as a solvent. With increasing water content in the mixture both I(1)/I(2) and the quantum yield decreased.
authors.affiliation: Department of Organic Chemistry, Faculty of Science, Institute of Molecular and Translational Medicine, Palacký University, Olomouc, Czech Republic. motyka@orgchem.upol.cz
authors.forename: Kamil
authors.initials: K
authors.lastname: Motyka
authors.forename: Barbora
authors.initials: B
authors.lastname: Vaňková
authors.forename: Jan
authors.initials: J
authors.lastname: Hlaváč
authors.forename: Miroslav
authors.initials: M
authors.lastname: Soural
authors.forename: Petr
authors.initials: P
authors.lastname: Funk
mesh_terms: D005453:Fluorescence; D006571:Heterocyclic Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D006912:Hydroxyquinolines / Q000737:chemistry*; D015394:Molecular Structure; D011687:Purines / Q000737:chemistry*; D013050:Spectrometry, Fluorescence; D013237:Stereoisomerism
chemical_list: D006571:Heterocyclic Compounds; D006912:Hydroxyquinolines; D011687:Purines; C030985:purine