title: [A case of Sjogren syndrome coexistent with MALT lymphoma occurring along the parotid gland and trachea].
abstract: A 62-year-old woman with Sjogren syndrome was admitted for computed tomographic (CT) evaluation of a thickened trachea and parotid tumor. She had been given a diagnosis of mucosa-associated lymphoid tissue (MALT) lymphoma 6 years previously, and had undergone surgical resection of the parotid tumor. Endoscopic examination revealed an annular tumor that had formed a stricture in the mid-trachea. Pathologic specimens were obtained by surgical resection of the parotid tumor and bronchoscopic biopsy of the tracheal tumor. Both histological examinations revealed MALT-type marginal zone B-cell lymphoma. Because CD20 immunostaining was positive, the patient received 6 cycles of rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisolone (CHOP) without any signs of major toxicity. All lesions disappeared after treatment, and this patient remained disease-free for 40 months.
authors.affiliation: Department of Internal, Nihonkoukan Hospital.
authors.forename: Kazuma
authors.initials: K
authors.lastname: Sekine
authors.forename: Naoki
authors.initials: N
authors.lastname: Miyao
authors.forename: Naoko
authors.initials: N
authors.lastname: Harada
authors.forename: Masaki
authors.initials: M
authors.lastname: Akao
authors.forename: Naoya
authors.initials: N
authors.lastname: Nakamura
authors.forename: Masahiro
authors.initials: M
authors.lastname: Kizaki
authors.forename: Osamu
authors.initials: O
authors.lastname: Suzuki
mesh_terms: D005260:Female; D006801:Humans; D018442:Lymphoma, B-Cell, Marginal Zone / Q000150:complications*; D008875:Middle Aged; D010307:Parotid Neoplasms / Q000150:complications*; D012859:Sjogren's Syndrome / Q000150:complications*; D014134:Tracheal Neoplasms / Q000150:complications*