title: [Safety of early cardiopulmonary exercise test in myocardial infarction patients with acute ST-elevation].
abstract: OBJECTIVE
  To investigate the safety of cardiopulmonary exercise testing (CPET) early after acute ST-elevation myocardial infarction (STEMI).
  
  
  METHODS
  We retrospectively reviewed 302 patients who underwent CPET early after STEMI in a single exercise laboratory. Demographic data, presence of concomitant diseases, characteristics of AMI, angiography findings and the safety of CPET were evaluated.
  
  
  RESULTS
  41.7% of the tests were reported to have stopped earlier than expected. The most common limiting symptoms were generalized fatigue (67.5%). None of the tests terminated because of severe arrhythmia, syncope or sudden death. In contrast to patients with incomplete revascularization (IR), the rate of stopping earlier than expected was lower in complete revascularization (CR) patients (35.1% vs. 49.6%, P=0.040). After being adjusted by the subjects' demographic features, clinical characteristics and cardiovascular risk factors, IR (P=0.013, OR=1.869, 95%CI 1.139 to 3.067) and left ventricular end-diastolic dimension (LVEDD, P=0.018, OR=1.064, 95%CI 1.011 to 1.121) were independent risk factors for the limiting symptoms of CPET.
  
  
  CONCLUSIONS
  The experience of this laboratory shows that CPET is relatively safe in patients early after STEMI. IR and LVEDD are independent risk factors for the limiting symptoms of CPET.
authors.affiliation: Department of Cardiology, Peking University Third Hospital, Key Laboratory of Cardiovascular Molecular Biology and Regulatory Peptides, Ministry of Health, Beijing 100191, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Zhao
authors.forename: Jin
authors.initials: J
authors.lastname: Bai
authors.forename: Fu-chun
authors.initials: FC
authors.lastname: Zhang
authors.forename: Hong-yan
authors.initials: HY
authors.lastname: Wang
authors.forename: Wei
authors.initials: W
authors.lastname: Gao
mesh_terms: D000368:Aged; D004562:Electrocardiography; D005080:Exercise Test / Q000009:adverse effects* / Q000379:methods*; D017079:Exercise Tolerance; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000503:physiopathology*; D012189:Retrospective Studies; D013997:Time Factors