title: Aristolactams from roots of Ottonia anisum (Piperaceae).
abstract: The Piperaceae species are known worldwide for its medicinal properties and its chemical compounds. In Brazil, many species of this family are distributed mainly in Amazon Region and in the Atlantic Forest. The genus Ottonia is known as source of amides, flavonoids, arilpropanoids and terpenes with record biological activities. Six aristolactams, including, aristolactam BII, piperolactam C, goniothalactam, stigmalactam, aristolactam AII and aristolactam BIII were isolated from roots of this species. GC-MS, 1H NMR and NOESY techniques were used to characterize these compounds. This is the first report about the occurrence of aristolactams in the Ottonia anisum Sprengel.
authors.affiliation: Núcleo de Pesquisas de Produtos Naturais (NPPN), Centro de Ciências da Saúde, Bloco H, Universidade Federal do Rio de Janeiro (UFRJ), CEP: 21941-590 - Rio de Janeiro, RJ, Brazil.
authors.forename: André M
authors.initials: AM
authors.lastname: Marques
authors.forename: Leosvaldo S M
authors.initials: LS
authors.lastname: Velozo
authors.forename: Davyson L
authors.initials: DL
authors.lastname: de Moreira
authors.forename: Elsie F
authors.initials: EF
authors.lastname: Guimarães
authors.forename: Maria Auxiliadora C
authors.initials: MA
authors.lastname: Kaplan
mesh_terms: D001938:Brazil; D008401:Gas Chromatography-Mass Spectrometry; D007769:Lactams / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D026321:Piperaceae / Q000737:chemistry*; D018517:Plant Roots / Q000737:chemistry
chemical_list: D007769:Lactams