title: Comparison of success rates of 'transvaginal aspiration and tetracycline sclerotherapy' versus 'only aspiration' in the management of non-neoplastic ovarian cysts.
abstract: OBJECTIVE
  To investigate the value of tetracycline sclerotherapy for management of recurrent or persisting non-neoplastic ovarian cysts in comparison to the aspiration without sclerotherapy.
  
  
  METHODS
  Ninety-six patients with proven non-neoplastic ovarian cysts were randomized into two groups. Group 1 patients underwent cyst aspiration together with tetracycline sclerotherapy (n=48). Group 2 patients underwent only cyst aspiration without tetracycline sclerotherapy (n=48). Then, all patients were followed up monthly with ultrasonography for 12months. The procedure was considered to have failed if the recurring cyst, detected by ultrasound, was 4cm in size or greater.
  
  
  RESULTS
  There were no differences between the two groups regarding demographic data, initial cyst volume and tumor markers. Recurrence rates within 12months were 14.6% in group 1 and 50% in group 2 (P<0.001).
  
  
  CONCLUSIONS
  Based on the recurrence rates, we suggest transvaginal aspiration together with tetracycline sclerotherapy rather than only simple transvaginal aspiration in the management of non-neoplastic ovarian cysts.
authors.affiliation: Dr Lutfi Kirdar Kartal Education and Research Hospital, Department of Obstetrics and Gynecology, Istanbul, Turkey. bulent1972kars@yahoo.com
authors.forename: Bulent
authors.initials: B
authors.lastname: Kars
authors.forename: Esra E
authors.initials: EE
authors.lastname: Buyukbayrak
authors.forename: A Yasemin K
authors.initials: AY
authors.lastname: Karsidag
authors.forename: Meltem
authors.initials: M
authors.lastname: Pirimoglu
authors.forename: Orhan
authors.initials: O
authors.lastname: Unal
authors.forename: Cem
authors.initials: C
authors.lastname: Turan
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008875:Middle Aged; D010048:Ovarian Cysts / Q000000981:diagnostic imaging / Q000601:surgery / Q000628:therapy*; D010053:Ovary / Q000000981:diagnostic imaging*; D012008:Recurrence; D015911:Sclerotherapy / Q000379:methods*; D013396:Suction; D013752:Tetracycline / Q000627:therapeutic use*; D016896:Treatment Outcome; D014463:Ultrasonography
chemical_list: D000900:Anti-Bacterial Agents; D013752:Tetracycline