title: [Sleep disorder and pain: the good hypnotic].
abstract: Chronic pain and sleep disorder can put the patient in a vicious circle (bidirectional relation between those two morbid entities). Clinical management must be global. The physiopathology includes chronic sleep deficit, mainly in deep sleep (the "restoring" sleep) generated principally by the prefrontal regions. These areas are also implicated in the modulation of pain. To break this "loops", we advocate an approach based on three main components: hygiene principles, cognitive and behavioral therapy, medications with analgesic and hypnotic proprieties.
authors.affiliation: Laboratoire du sommeil-EEG Service de Neuropsychiatrie, HUG, Genève. stephen.perrig@hcuge.ch
authors.forename: S
authors.initials: S
authors.lastname: Perrig
authors.forename: K
authors.initials: K
authors.lastname: Espa-Cervena
authors.forename: J L
authors.initials: JL
authors.lastname: Pépin
mesh_terms: D000700:Analgesics / Q000627:therapeutic use*; D018712:Analgesics, Non-Narcotic / Q000627:therapeutic use; D000701:Analgesics, Opioid / Q000627:therapeutic use; D000818:Animals; D000927:Anticonvulsants / Q000627:therapeutic use*; D001521:Behavior Therapy; D001921:Brain / Q000503:physiopathology*; D002908:Chronic Disease; D015928:Cognitive Behavioral Therapy; D004359:Drug Therapy, Combination; D019317:Evidence-Based Medicine; D006801:Humans; D006993:Hypnotics and Sedatives / Q000627:therapeutic use*; D008019:Life Style; D008550:Melatonin / Q000627:therapeutic use; D010146:Pain / Q000188:drug therapy* / Q000503:physiopathology; D059408:Pain Management; D010919:Placebos / Q000627:therapeutic use; D007319:Sleep Initiation and Maintenance Disorders / Q000188:drug therapy* / Q000503:physiopathology / Q000628:therapy; D012978:Sodium Oxybate / Q000627:therapeutic use; D016896:Treatment Outcome
chemical_list: D000700:Analgesics; D018712:Analgesics, Non-Narcotic; D000701:Analgesics, Opioid; D000927:Anticonvulsants; D006993:Hypnotics and Sedatives; D010919:Placebos; D012978:Sodium Oxybate; D008550:Melatonin