title: Design and synthesis of C2-symmetric N-heterocyclic carbene precursors and metal carbenoids.
abstract: Chiral, C(2)-symmetric imidazolium and imidazolinium ions, as well as the corresponding copper- or silver-bound carbenoids, have been prepared. Structural study of these compounds by X-ray crystallography reveals a chiral pocket that surrounds the putative carbene site or the metal-carbene bond, at carbon 2, in three of the four ligands prepared. Preliminary investigation into the application of these complexes has shown one of them to be highly enantioselective in the hydrosilylation of acetophenone.
authors.affiliation: Department of Chemistry and Biochemistry, University of Arkansas, Fayetteville, Arkansas 72701, USA.
authors.forename: Abigail
authors.initials: A
authors.lastname: Albright
authors.forename: Daniel
authors.initials: D
authors.lastname: Eddings
authors.forename: Regina
authors.initials: R
authors.lastname: Black
authors.forename: Christopher J
authors.initials: CJ
authors.lastname: Welch
authors.forename: Nikolay N
authors.initials: NN
authors.lastname: Gerasimchuk
authors.forename: Robert E
authors.initials: RE
authors.lastname: Gawley
mesh_terms: D015195:Drug Design; D006571:Heterocyclic Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D008670:Metals / Q000737:chemistry*; D008697:Methane / Q000031:analogs & derivatives* / Q000737:chemistry
chemical_list: D006571:Heterocyclic Compounds; D008670:Metals; C030011:carbene; D008697:Methane