title: Pneumococcal pneumonia complicating purulent pericarditis in a previously healthy girl: a rare yet possible fatal complication in the antibiotic era.
abstract: Purulent pericarditis is an extremely rare complication of invasive Streptococcus pneumoniae infection among children in the antibiotic era, and its mortality remains high if left untreated. This report involves a 4½-year-old girl who presented to our emergency department with productive cough, shortness of breath, and left-sided chest pain with a diagnosis of pneumococcal pneumonia. She subsequently developed life-threatening conditions including bilateral empyema with respiratory failure, purulent pericarditis, and multiple organ failure leading to death. The case highlights that purulent pericarditis is a rare yet possible disorder complicating pneumococcal disease in the antibiotic era. The increase in strains resistant to penicillin should alert emergency physicians to the potential for reemergence of pneumococcal pericarditis in children.
authors.affiliation: Department of Pediatrics, Chung Shan Medical University Hospital, Taichung, Taiwan.
authors.forename: Fong-Fong
authors.initials: FF
authors.lastname: Lim
authors.forename: Hung-Ming
authors.initials: HM
authors.lastname: Chang
authors.forename: Ko-Huang
authors.initials: KH
authors.lastname: Lue
authors.forename: Ji-Nan
authors.initials: JN
authors.lastname: Sheu
mesh_terms: D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D002443:Ceftriaxone / Q000008:administration & dosage; D002675:Child, Preschool; D016724:Empyema, Pleural / Q000209:etiology; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D010493:Pericarditis / Q000209:etiology* / Q000382:microbiology; D010996:Pleural Effusion / Q000000981:diagnostic imaging; D011018:Pneumonia, Pneumococcal / Q000150:complications* / Q000188:drug therapy / Q000628:therapy; D012121:Respiration, Artificial; D013907:Thoracostomy; D014463:Ultrasonography; D014640:Vancomycin / Q000008:administration & dosage
chemical_list: D000900:Anti-Bacterial Agents; D014640:Vancomycin; D002443:Ceftriaxone