title: Assessor-blinded study of the metabolic syndrome and surrogate markers of increased cardiovascular risk in children with moderate-to-severe psoriasis compared with age-matched population of children with warts.
abstract: Adult patients with psoriasis have an increased prevalence of the metabolic syndrome (MetS) and cardiovascular disease (CVD) risk factors due to elevations of Tumor Necrosis Factor and other inflammatory cytokines.1,2 Recently, higher rates of hyperlipidemia, obesity, hypertension, and diabetes mellitus were seen in patients with juvenile psoriasis.3 Here, we report the interim results of an ongoing study of MetS and CVD risk factors in pediatric psoriasis patients.
authors.affiliation: Tufts University School of Medicine, Boston, MA 02111, USA. eva.volf@tufts.edu
authors.forename: Eva M
authors.initials: EM
authors.lastname: Volf
authors.forename: Danielle E
authors.initials: DE
authors.lastname: Levine
authors.forename: Melissa A
authors.initials: MA
authors.lastname: Michelon
authors.forename: Shiu-Chung
authors.initials: SC
authors.lastname: Au
authors.forename: Eshan
authors.initials: E
authors.lastname: Patvardhan
authors.forename: Nicole
authors.initials: N
authors.lastname: Dumont
authors.forename: Daniel S
authors.initials: DS
authors.lastname: Loo
authors.forename: Jeffrey
authors.initials: J
authors.lastname: Kuvin
authors.forename: Alice B
authors.initials: AB
authors.lastname: Gottlieb
mesh_terms: D000293:Adolescent; D015415:Biomarkers / Q000378:metabolism; D002318:Cardiovascular Diseases / Q000150:complications / Q000453:epidemiology* / Q000209:etiology / Q000473:pathology; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D024821:Metabolic Syndrome / Q000150:complications / Q000453:epidemiology* / Q000473:pathology; D011565:Psoriasis / Q000150:complications / Q000453:epidemiology* / Q000473:pathology; D012307:Risk Factors; D016037:Single-Blind Method; D014860:Warts / Q000150:complications / Q000453:epidemiology* / Q000473:pathology
chemical_list: D015415:Biomarkers