title: Biocompatibility evaluation of nano hydroxyapatite-starch biocomposites.
abstract: In this work, we report the synthesis and characterization of nano hydroxyapatite (nHAp) in the presence of starch matrix via a biomimetic process for in vitro biocompatibility evaluation. Characterization of the samples was carried out using X-ray diffraction (XRD) and Fourier Transform infrared spectroscopy (FT-IR). The Size and morphology of the nHAp samples were determined using scanning and transmission electron microscopy (SEM and TEM). The results show that, the shape and morphology of nHAp is influenced by the presence of starch as a template agent. It leads to formation of rod-like nHAp. Cell culture and MTT assays were performed for in vitro biocompatibility. They show that n-HAp can affect the proliferation of cells and the n-HAp/starch biocomposites have no negative effect on the cell morphology, viability and proliferation.
authors.affiliation: Department of Chemistry, Lahijan Branch, Islamic Azad University, Lahijan 4416939515, Iran.
authors.forename: M
authors.initials: M
authors.lastname: Meskinfam
authors.forename: M A S
authors.initials: MA
authors.lastname: Sadjadi
authors.forename: H
authors.initials: H
authors.lastname: Jazdarreh
authors.forename: K
authors.initials: K
authors.lastname: Zare
mesh_terms: D001854:Bone Marrow Cells / Q000737:chemistry / Q000187:drug effects; D049109:Cell Proliferation; D017886:Durapatite / Q000737:chemistry* / Q000494:pharmacology; D006801:Humans; D008422:Materials Testing; D008855:Microscopy, Electron, Scanning; D008954:Models, Biological; D049329:Nanostructures / Q000737:chemistry*; D017550:Spectroscopy, Fourier Transform Infrared; D013213:Starch / Q000737:chemistry* / Q000494:pharmacology; D013234:Stem Cells / Q000737:chemistry / Q000166:cytology / Q000187:drug effects; D014961:X-Ray Diffraction
chemical_list: D013213:Starch; D017886:Durapatite