title: Direct synthesis of enaminone functionalized biaryl ethers by CuI-catalyzed O-arylation of enaminone functionalized phenols.
abstract: The O-arylation of o-enaminone functionalized phenols, namely, (E)-3-(dimethylamino)-1-(2-hydroxyphenyl)prop-2-en-1-ones, has been achieved via a self-promoted process in the presence of CuI, which provided a class of new biaryl ethers bearing a reactive enaminone fragment. The reactions were performed under mild conditions and the functionalized biaryl ether products have been found as useful building blocks for the assembly of heterocyclic compounds.
authors.affiliation: College of Chemistry and Chemical Engineering, Jiangxi Normal University, Nanchang, 330022, China. wanjieping@gmail.com
authors.forename: Jie-Ping
authors.initials: JP
authors.lastname: Wan
authors.forename: Chunping
authors.initials: C
authors.lastname: Wang
authors.forename: Yunyun
authors.initials: Y
authors.lastname: Liu
mesh_terms: D002384:Catalysis; D060326:Chemistry Techniques, Synthetic; D003300:Copper / Q000737:chemistry*; D004987:Ethers / Q000138:chemical synthesis* / Q000737:chemistry; D007454:Iodides / Q000737:chemistry*; D015394:Molecular Structure; D010636:Phenols / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D004987:Ethers; D007454:Iodides; D010636:Phenols; D003300:Copper; C073870:cuprous iodide