title: Calorie supply does not alleviate running-based taste aversion learning in rats.
abstract: Voluntary running establishes aversion to the paired taste in rats. A proposed mechanism underlying this taste aversion learning is energy expenditure caused by the running. The energy expenditure hypothesis predicts that running-based taste aversion should be alleviated by a calorie supply since this would compensate for the energy expended by running. Accordingly, running-based taste aversion would be less readily established to a caloric substance (20% sucrose solution) than to a noncaloric substance (0.2% sodium saccharin solution). Because the sucrose and saccharin aversions were equivalent in Experiment 1, the validity of the energy expenditure hypothesis was questioned. Experiments 2 and 3 also pose a problem for this hypothesis, as post-session calorie supply by glucose tablets failed to alleviate running-based aversion to salty water.
authors.affiliation: Department of Psychological Science, Kwansei Gakuin University, Nishinomiya, 662-8501, Japan. nakajima@kwansei.ac.jp
authors.forename: Sadahiko
authors.initials: S
authors.lastname: Nakajima
mesh_terms: D000818:Animals; D003214:Conditioning, Classical / Q000187:drug effects*; D003520:Cyclophosphamide; D002149:Energy Intake / Q000187:drug effects*; D004734:Energy Metabolism; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D015203:Reproducibility of Results; D012107:Research Design; D012420:Running / Q000502:physiology*; D012439:Saccharin / Q000008:administration & dosage; D013395:Sucrose / Q000008:administration & dosage; D013649:Taste
chemical_list: D013395:Sucrose; D003520:Cyclophosphamide; D012439:Saccharin