title: Thirteen-month-old boy with malignant lymphoma having symptoms mimicking acute otitis media and mastoiditis with facial palsy.
abstract: Non-Hodgkin diffuse large B-cell lymphomas of the mastoid that extend from the nasopharynx are extremely rare in children. Moreover, in lymphoproliferative diseases, the presence of otoneurological signs prior to systemic disease involvement is rare. Here, we present a rare case of non-Hodgkin B-cell lymphoma invading the middle ear and mastoid in a 1-year-old boy that mimicked acute mastoiditis with complete facial nerve palsy. As this case illustrates, physicians should consider a diagnosis of malignant lymphoma if a patient presents with otitis media and mastoiditis accompanied by facial palsy.
authors.affiliation: Department of Otolaryngology, Head and Neck Surgery, Keio University School of Medicine, Tokyo, Japan. skan@a7.keio.jp
authors.forename: Sho
authors.initials: S
authors.lastname: Kanzaki
authors.forename: Hideyuki
authors.initials: H
authors.lastname: Saito
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Mori
authors.forename: Noriko
authors.initials: N
authors.lastname: Shimasaki
authors.forename: Makio
authors.initials: M
authors.lastname: Mukai
authors.forename: Kaoru
authors.initials: K
authors.lastname: Ogawa
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D016393:Lymphoma, B-Cell / Q000175:diagnosis* / Q000188:drug therapy / Q000601:surgery; D008279:Magnetic Resonance Imaging; D008297:Male; D008417:Mastoiditis / Q000175:diagnosis*; D010033:Otitis Media / Q000175:diagnosis*; D016879:Salvage Therapy; D014057:Tomography, X-Ray Computed
chemical_list: D000970:Antineoplastic Agents