title: A randomized clinical trial to compare levonorgestrel-releasing intrauterine system (Mirena) vs trans-cervical endometrial resection for treatment of menorrhagia.
abstract: OBJECTIVE
  To compare the acceptability, efficacy, adverse effects, and user satisfaction of the levonorgestrel intrauterine system (LNG-IUS) and trans-cervical resection of the endometrium (TCRE) for the treatment of menorrhagia.
  
  
  METHODS
  104 women with menorrhagia were divided into 2 groups: 52 women had the LNG-IUS inserted and 52 underwent TCRE. Menstrual pattern, pictorial blood loss assessment chart score, adverse effects, and rates of acceptability and satisfaction, were recorded at 6 and 12 months after the procedure.
  
  
  RESULTS
  After a year there were reductions of 93.9% and 88.4% in menstrual blood loss in the TCRE and LNG-IUS groups, respectively. Amenorrhea was more common in the TCRE group and spotting and systemic effects in the LNG-IUS group. Satisfaction rates of the TCRE group were higher than the LNG-IUS group (80.8% vs 69.2%), but the difference was not statistically significant.
  
  
  CONCLUSIONS
  Although both treatments were found to be equally effective, LNG-IUS was less invasive and can be advised for younger women with a desire to preserve fertility.
authors.affiliation: Valie-Asr Reproductive Health Research Center, Valie-Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran;
authors.forename: Shirin
authors.initials: S
authors.lastname: Ghazizadeh
authors.forename: Fatemeh
authors.initials: F
authors.lastname: Bakhtiari
authors.forename: Haleh
authors.initials: H
authors.lastname: Rahmanpour
authors.forename: Fatemeh
authors.initials: F
authors.lastname: Davari-Tanha
authors.forename: Fatemeh
authors.initials: F
authors.lastname: Ramezanzadeh