title: [Epithelial neoplasia of the appendix: what has recently changed?].
abstract: Appendicular tumors are mostly found incidentally in up to 1.5% of all appendectomies. Neuroendocrine tumors are the commonest malignancies, and are associated with an excellent long-term prognosis. While small lesions located at the appendicular tip can be treated with simple appendectomy, advanced tumors require right hemicolectomy. Goblet cell carcinoids are rare tumors showing a mixed phenotype. Long-term outcome is impaired, and for most cases a right hemicolectomy is mandatory. Colonic-type adenocarcinomas have a similar behavior like conventional colonic cancer and should be treated similarly. Mucinous neoplasias possess the characteristic of extensive mucin production with intraperitoneal spread. Treatment options are ranging from right hemicolectomy to multivisceral resection with intraperitoneal chemotherapy.
authors.affiliation: Service de chirurgie viscérale, Département de chirurgie, CHUV, Lausanne. styliani.mantziari@chuv.ch
authors.forename: S
authors.initials: S
authors.lastname: Mantziari
authors.forename: F
authors.initials: F
authors.lastname: Grass
authors.forename: N
authors.initials: N
authors.lastname: Demartines
authors.forename: M
authors.initials: M
authors.lastname: Schaefer
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology / Q000601:surgery; D000970:Antineoplastic Agents / Q000008:administration & dosage; D001062:Appendectomy; D001063:Appendiceal Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery*; D002276:Carcinoid Tumor / Q000473:pathology / Q000601:surgery; D003082:Colectomy; D006801:Humans; D033162:Incidental Findings; D007274:Injections, Intraperitoneal; D009367:Neoplasm Staging; D009375:Neoplasms, Glandular and Epithelial / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery*; D018358:Neuroendocrine Tumors / Q000473:pathology / Q000601:surgery; D011379:Prognosis; D016896:Treatment Outcome
chemical_list: D000970:Antineoplastic Agents