title: Identification of sexual networks through molecular typing of quinolone-resistant Neisseria gonorrhoeae in Ontario, Canada.
abstract: Neisseria gonorrhoeae multi-antigen sequence typing technique demonstrated multiple sexual transmission networks in Ontario, Canada. Isolates with novel sequences had higher odds of originating in Toronto but had no association with heightened population-level quinolone exposure. Neisseria gonorrhoeae multi-antigen sequence typing technique can be a useful tool for investigation of multidrug-resistant N. gonorrhoeae emergence in North America.
authors.affiliation: University of Pennsylvania, Philadelphia, PA, USA. otak@email.chop.edu
authors.forename: Kaede V
authors.initials: KV
authors.lastname: Ota
authors.forename: Lai-King
authors.initials: LK
authors.lastname: Ng
authors.forename: Roberto G
authors.initials: RG
authors.lastname: Melano
authors.forename: Irene E
authors.initials: IE
authors.lastname: Martin
authors.forename: Elizabeth M
authors.initials: EM
authors.lastname: Brown
authors.forename: Susan E
authors.initials: SE
authors.lastname: Richardson
authors.forename: David N
authors.initials: DN
authors.lastname: Fisman
authors.forename: Donald E
authors.initials: DE
authors.lastname: Low
authors.forename: Frances B
authors.initials: FB
authors.lastname: Jamieson
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000554:Ambulatory Care Facilities; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D004269:DNA, Bacterial / Q000235:genetics; D024901:Drug Resistance, Multiple, Bacterial / Q000187:drug effects*; D005260:Female; D006069:Gonorrhea / Q000453:epidemiology / Q000382:microbiology* / Q000635:transmission; D018451:Homosexuality, Male; D006801:Humans; D016015:Logistic Models; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D058889:Molecular Typing / Q000379:methods; D009344:Neisseria gonorrhoeae / Q000145:classification* / Q000187:drug effects / Q000235:genetics; D009864:Ontario / Q000453:epidemiology; D015363:Quinolones / Q000494:pharmacology*; D012725:Sexual Behavior; D055815:Young Adult
chemical_list: D000900:Anti-Bacterial Agents; D004269:DNA, Bacterial; D015363:Quinolones