title: The use of gold nanoparticle aggregation for DNA computing and logic-based biomolecular detection.
abstract: The use of DNA molecules as a physical computational material has attracted much interest, especially in the area of DNA computing. DNAs are also useful for logical control and analysis of biological systems if efficient visualization methods are available. Here we present a quick and simple visualization technique that displays the results of the DNA computing process based on a colorimetric change induced by gold nanoparticle aggregation, and we apply it to the logic-based detection of biomolecules. Our results demonstrate its effectiveness in both DNA-based logical computation and logic-based biomolecular detection.
authors.affiliation: School of Computer Science and Engineering, Seoul National University, 599 Gwanak-ro, Gwanak-gu, Seoul 151-742, Korea.
authors.forename: In-Hee
authors.initials: IH
authors.lastname: Lee
authors.forename: Kyung-Ae
authors.initials: KA
authors.lastname: Yang
authors.forename: Ji-Hoon
authors.initials: JH
authors.lastname: Lee
authors.forename: Ji-Yoon
authors.initials: JY
authors.lastname: Park
authors.forename: Young Gyu
authors.initials: YG
authors.lastname: Chai
authors.forename: Jae-Hoon
authors.initials: JH
authors.lastname: Lee
authors.forename: Byoung-Tak
authors.initials: BT
authors.lastname: Zhang