title: Acanthosis nigricans as a local cutaneous side effect of repeated human insulin injections.
abstract: Acanthosis nigricans is a hyperkeratotic lesion of the epidermis associated with insulin resistance. We present a diabetic patient with acanthosis nigricans at the insulin injection site on the abdominal wall. Neglecting rotation of sites for insulin injections and local hyperinsulinemia may play a role in the development of acanthosis nigricans.
authors.affiliation: Department of Endocrinology and Angiology, Bajcsy-Zsilinszky Hospital, Maglódi út 89-91, Budapest 1106, Hungary.
authors.forename: Katalin
authors.initials: K
authors.lastname: Buzási
authors.forename: Zoltán
authors.initials: Z
authors.lastname: Sápi
authors.forename: György
authors.initials: G
authors.lastname: Jermendy
mesh_terms: D000052:Acanthosis Nigricans / Q000139:chemically induced* / Q000473:pathology; D000368:Aged; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000175:diagnosis / Q000188:drug therapy*; D006801:Humans; D007004:Hypoglycemic Agents / Q000008:administration & dosage / Q000009:adverse effects*; D007267:Injections; D007328:Insulin / Q000008:administration & dosage / Q000009:adverse effects*; D008297:Male; D012867:Skin / Q000187:drug effects* / Q000473:pathology
chemical_list: D007004:Hypoglycemic Agents; D007328:Insulin