title: Subtypes of dementia: a study from a memory clinic in India.
abstract: BACKGROUND
  The clinical syndrome of dementia consists of several subtypes that are distinct in their etiology, clinical profile, management, and outcome. Limited specialized services are available for dementia patients in India. We report the profile of dementia subtypes from a clinic-based dementia registry in India.
  
  
  METHODS
  Consecutive dementia patients were investigated with clinical evaluation, neuropsychological tests modified for local use, and brain imaging.
  
  
  RESULTS
  In 347 consecutive dementia patients, Alzheimer's disease was the most common subtype of dementia (38.3%), followed by a high proportion of vascular dementia (25.4%). Frontotemporal dementia syndromes were not uncommon (18.7%). Dementia with Lewy bodies was encountered in 8.9% of the patients, and mixed dementia was found in 8.6%. The mean age of the group at presentation was 66.3 years, nearly a decade younger than in developed countries. The proportion of patients with early-onset dementia was high (49.9%).
  
  
  CONCLUSIONS
  Our results demonstrate that the clinical profiles of dementia subtypes in a clinic population are influenced by the population's demographic profile, cardiovascular risk factor burden, sociocultural attitudes about cognitive impairment, and possibly genetic factors.
authors.affiliation: Department of Neurology, Nizam’s Institute of Medical Sciences, Punjagutta, Hyderabad 500082, India. alladisuvarna@hotmail.com
authors.forename: Suvarna
authors.initials: S
authors.lastname: Alladi
authors.forename: Shailaja
authors.initials: S
authors.lastname: Mekala
authors.forename: Santhoshi Kumari
authors.initials: SK
authors.lastname: Chadalawada
authors.forename: Sireesha
authors.initials: S
authors.lastname: Jala
authors.forename: Rukmini
authors.initials: R
authors.lastname: Mridula
authors.forename: Subhash
authors.initials: S
authors.lastname: Kaul
mesh_terms: D000328:Adult; D000367:Age Factors; D017668:Age of Onset; D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000145:classification / Q000523:psychology; D000554:Ambulatory Care Facilities; D018888:Aphasia, Primary Progressive / Q000145:classification / Q000523:psychology; D003071:Cognition / Q000502:physiology; D003704:Dementia / Q000145:classification* / Q000453:epidemiology / Q000523:psychology*; D015140:Dementia, Vascular / Q000145:classification / Q000523:psychology; D003952:Diagnostic Imaging; D004522:Educational Status; D005260:Female; D057174:Frontotemporal Lobar Degeneration / Q000145:classification / Q000523:psychology; D006801:Humans; D007194:India / Q000453:epidemiology; D007802:Language; D020961:Lewy Body Disease / Q000145:classification / Q000523:psychology; D008297:Male; D008569:Memory Disorders / Q000628:therapy*; D008875:Middle Aged; D009483:Neuropsychological Tests; D012042:Registries; D012923:Social Class