title: Epithelial interleukin-8 responses to oral bacterial biofilms.
abstract: An in vitro model of bacterial biofilms on rigid gas-permeable contact lenses (RGPLs) was developed to challenge oral epithelial cells. This novel model provided seminal data on oral biofilm-host cell interactions, and with selected bacteria, the biofilms were more effective than their planktonic counterparts at stimulating host cell responses.
authors.affiliation: Center for Oral Health Research, College of Dentistry, University of Kentucky, 414 HSRB, 1095 VA Drive, Lexington, KY 40536, USA. rpeyy1@email.uky.edu
authors.forename: R
authors.initials: R
authors.lastname: Peyyala
authors.forename: S
authors.initials: S
authors.lastname: Kirakodu
authors.forename: K F
authors.initials: KF
authors.lastname: Novak
authors.forename: J L
authors.initials: JL
authors.lastname: Ebersole
mesh_terms: D001419:Bacteria / Q000276:immunology*; D018441:Biofilms; D004847:Epithelial Cells / Q000276:immunology* / Q000382:microbiology*; D054884:Host-Pathogen Interactions; D016209:Interleukin-8 / Q000378:metabolism*; D009061:Mouth Mucosa / Q000276:immunology* / Q000382:microbiology*
chemical_list: D016209:Interleukin-8