title: [Avascular necrosis of the femoral head in children with sickle cell disease (Libreville, Gabon)].
abstract: We present the clinical aspects of avascular osteonecrosis in children with sickle-cell disease and emphasize the need for early detection of this necrosis of the femoral head, which is often nearly or totally asymptomatic. This retrospective descriptive study covers the 10 years from January 1989 through December 1999 and includes 22 homozygous (Hb-SS) children and adolescents with sickle-cell disease, all presenting pain in the hip and/or limping. The sex ratio was 2.6 (72% boys). Epiphyseal infarction in these children can concern the femoral as well as the humeral head. Femoral osteonecrosis is disabling and often has severe complications, involving not only functional prognosis but also growth potential. Patient and family education is essential to facilitate early diagnosis and treatment and avoid severe consequences in adulthood.
authors.affiliation: Université des sciences de la santé, Département de pédiatrie, Libreville, Gabon. jfmouba@yahoo.fr
authors.forename: John Florent
authors.initials: JF
authors.lastname: Mouba
authors.forename: Mylène
authors.initials: M
authors.lastname: Mimbila
authors.forename: Léonie Ester
authors.initials: LE
authors.lastname: Lentombo
authors.forename: Jean-François
authors.initials: JF
authors.lastname: Thardin
authors.forename: Alain
authors.initials: A
authors.lastname: Ondo
mesh_terms: D000293:Adolescent; D000755:Anemia, Sickle Cell / Q000150:complications*; D002648:Child; D005260:Female; D005271:Femur Head Necrosis / Q000175:diagnosis / Q000209:etiology*; D005681:Gabon; D006801:Humans; D008297:Male; D012189:Retrospective Studies