title: Streptococcus pneumoniae serotypes isolated from the middle ear of Mexican children diagnosed with acute otitis media.
abstract: OBJECTIVE
  The aim of this study was to identify the etiology and the serotypes of S. pneumoniae (Sp) in Mexican children with acute otitis media (AOM).
  
  
  METHODS
  The study includessamples frompatientsdiagnosed with AOM at the Federico Gomez Children's Hospital of Mexico (2002-2003),with positive culture for Sp bacteriologically confirmed in middle ear fluid obtained by tympanocentesis. All Sp were serotyped. A total of 138 samples from 135 children with AOM were included.
  
  
  RESULTS
  Sp was isolated in 72 samples from 70 children. Sixty (85.7%) were previously healthy and 10 (14.3%) were immunocompromised. The most common serotypes were 6B and 19F (16.67%), and 6 A, 14 and 23F (15.27%).
  
  
  CONCLUSIONS
  The distribution of serotypes among the children with AOM in the study is similar to that reported in developing cities, and 63.9% of the isolated serotypes are found to be included in the 7-Valent Pneumococcal Conjugate Vaccine (PCV), 68.1% in the 10-Valent PCV and 83.3% in 13-Valent PCV.
authors.affiliation: Hospital Infantil de México Federico Gómez, México, DF, México. dgbarreto30@hotmail.com
authors.forename: Demóstenes
authors.initials: D
authors.lastname: Gómez-Barreto
authors.forename: Luz Elena Espinosa
authors.initials: LE
authors.lastname: de Los Monteros
authors.forename: Claudia
authors.initials: C
authors.lastname: López-Enríquez
authors.forename: Romeo Rodríguez
authors.initials: RR
authors.lastname: Suarez
authors.forename: Carlos
authors.initials: C
authors.lastname: de la Torre
mesh_terms: D000208:Acute Disease; D002648:Child; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D003906:Developing Countries; D004432:Ear, Middle / Q000382:microbiology*; D006776:Hospitals, Pediatric / Q000706:statistics & numerical data; D006801:Humans; D016867:Immunocompromised Host; D007223:Infant; D008800:Mexico / Q000453:epidemiology; D010033:Otitis Media / Q000453:epidemiology / Q000382:microbiology*; D011008:Pneumococcal Infections / Q000453:epidemiology / Q000382:microbiology*; D022242:Pneumococcal Vaccines / Q000276:immunology; D012189:Retrospective Studies; D012703:Serotyping; D013296:Streptococcus pneumoniae / Q000145:classification* / Q000302:isolation & purification; D014611:Vaccination / Q000706:statistics & numerical data; D018074:Vaccines, Conjugate / Q000276:immunology; D014774:Virulence
chemical_list: D022242:Pneumococcal Vaccines; D018074:Vaccines, Conjugate