title: Folic acid and colorectal cancer: unwarranted fears.
abstract: OBJECTIVE
  Some of my female patients are afraid of taking folic acid because they "fear cancer." What is the evidence for this?
  
  
  CONCLUSIONS
  Theoretical evidence in experimental models is sharply contrasted by 3 recent meta-analyses of randomized and observational studies. Women planning to become pregnant should supplement with the folate dose they need to prevent neural tube defects.
authors.affiliation: Motherisk Team at Hospital for Sick Children in Toronto, Ont.
authors.forename: Gideon
authors.initials: G
authors.lastname: Koren
mesh_terms: D015179:Colorectal Neoplasms / Q000139:chemically induced*; D019317:Evidence-Based Medicine; D005260:Female; D005492:Folic Acid / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D009436:Neural Tube Defects / Q000517:prevention & control; D019370:Observation; D011247:Pregnancy; D016032:Randomized Controlled Trials as Topic
chemical_list: D005492:Folic Acid