title: Readily accessible chiral diene ligands for Rh-catalyzed enantioselective conjugate additions of boronic acids.
abstract: Enabled by the broad scope of the Pd-catalyzed asymmetric alkylation of meso- and d,l-divinylethylene carbonate, several chiral diene ligands were prepared in two steps from commercial materials. Subsequently, these ligands were evaluated in the Rh-catalyzed asymmetric conjugate addition of boronic acids to enones.
authors.affiliation: Department of Chemistry, Stanford University, Stanford, California 94305-5080, USA. bmtrost@stanford.edu
authors.forename: Barry M
authors.initials: BM
authors.lastname: Trost
authors.forename: Aaron C
authors.initials: AC
authors.lastname: Burns
authors.forename: Thomas
authors.initials: T
authors.lastname: Tautz
mesh_terms: D001897:Boronic Acids / Q000737:chemistry*; D002384:Catalysis; D003516:Cycloparaffins / Q000737:chemistry*; D006844:Hydrocarbons, Cyclic / Q000138:chemical synthesis* / Q000737:chemistry; D008024:Ligands; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry; D010165:Palladium / Q000737:chemistry; D012238:Rhodium / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D001897:Boronic Acids; D003516:Cycloparaffins; D006844:Hydrocarbons, Cyclic; D008024:Ligands; D009942:Organometallic Compounds; D010165:Palladium; D012238:Rhodium