title: Is rTMS an effective therapeutic strategy that can be used to treat Parkinson's disease?
abstract: Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive procedure whereby a pulsed magnetic field stimulates electrical activity in the brain. Parkinson's disease (PD) is a neurodegenerative process characterized by numerous motor and nonmotor clinical manifestations for which effective, mechanism-based treatments remain elusive. Consequently, more advanced non-invasive therapeutic methods are required. A possible method of rehabilitation that may be effective and potentially viable for use in clinical practice is rTMS. Here, we focus on the basic foundation of rTMS, the main findings of rTMS from animal models, the effects of rTMS on sensorimotor integration in patients with PD, and the experimental advances of rTMS that may become a viable clinical application to treat the disease.
authors.affiliation: Department of Neurology, Philipps University-Marburg, Germany. arias@exp-neuro.de
authors.forename: Oscar
authors.initials: O
authors.lastname: Arias-Carrion
authors.forename: Sergio
authors.initials: S
authors.lastname: Machado
authors.forename: Flavia
authors.initials: F
authors.lastname: Paes
authors.forename: Bruna
authors.initials: B
authors.lastname: Velasques
authors.forename: Silmar
authors.initials: S
authors.lastname: Teixeira
authors.forename: Lizbeth
authors.initials: L
authors.lastname: Cardenas-Morales
authors.forename: Roberto
authors.initials: R
authors.lastname: Piedade
authors.forename: Pedro
authors.initials: P
authors.lastname: Ribeiro
authors.forename: Antonio E
authors.initials: AE
authors.lastname: Nardi
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D006801:Humans; D009410:Nerve Degeneration / Q000534:rehabilitation / Q000628:therapy; D010300:Parkinson Disease / Q000534:rehabilitation* / Q000628:therapy*; D050781:Transcranial Magnetic Stimulation / Q000379:methods* / Q000639:trends*