title: Comparison of multilocus variable-number tandem-repeat analysis and multilocus sequence typing for differentiation of hemolytic-uremic syndrome-associated Escherichia coli (HUSEC) collection strains.
abstract: Multilocus variable-number tandem-repeat analysis (MLVA) was compared to multilocus sequence typing (MLST) to differentiate hemolytic uremic syndrome-associated enterohemorrhagic Escherichia coli strains. Although MLVA--like MLST--was highly discriminatory (index of diversity, 0.988 versus 0.984), a low level of concordance demonstrated the limited ability of MLVA to reflect long-term evolutionary events.
authors.affiliation: Institute of Hygiene and National Consulting Laboratory for Hemolytic Uremic Syndrome, University Hospital Münster, Robert-Koch-Strasse 41, 48149 Münster, Germany.
authors.forename: Christian
authors.initials: C
authors.lastname: Jenke
authors.forename: Björn Arne
authors.initials: BA
authors.lastname: Lindstedt
authors.forename: Dag
authors.initials: D
authors.lastname: Harmsen
authors.forename: Helge
authors.initials: H
authors.lastname: Karch
authors.forename: Lin Thorstensen
authors.initials: LT
authors.lastname: Brandal
authors.forename: Alexander
authors.initials: A
authors.lastname: Mellmann
mesh_terms: D054324:Enterohemorrhagic Escherichia coli / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification; D004927:Escherichia coli Infections / Q000150:complications* / Q000382:microbiology*; D006463:Hemolytic-Uremic Syndrome / Q000382:microbiology*; D006801:Humans; D018598:Minisatellite Repeats; D058889:Molecular Typing / Q000379:methods*; D058885:Multilocus Sequence Typing / Q000379:methods*