title: Aggressive behavior in patients with dementia: correlates and management.
abstract: OBJECTIVE
  To consider the phenomenon of aggressive behavior perpetrated by people with dementia.
  
  
  METHODS
  We searched electronic databases and key journals using the search terms: aggressive behavior; dementia; behavioral and psychological symptoms.
  
  
  RESULTS
  Aggressive behavior (AB) is probably one of the principal problems in dementia. Aggression is linked to internal factors (depression, psychosis, pain) and external determinants (caregiver burden, social stimulation, quality of caregiver-patient relationship). It has been suggested that challenging behavior in people with dementia reflects their premorbid personality traits.
  
  
  CONCLUSIONS
  Over the course of the illness AB occurs in 30 to 50% of patients and causes extreme stress for caregivers. Careful identification of target symptoms and their consequences, non-pharmacological approaches, and use of the least harmful medication for the shortest period of time should be the guiding principle of treatment.
authors.affiliation: Neurolocy Unit Department of Psychiatry, Versilia Hospital, Lido di Camaiore, Italy. cprgrl@gmail.com
authors.forename: Gabriele
authors.initials: G
authors.lastname: Cipriani
authors.forename: Marcella
authors.initials: M
authors.lastname: Vedovello
authors.forename: Angelo
authors.initials: A
authors.lastname: Nuti
authors.forename: Mario
authors.initials: M
authors.lastname: Di Fiorino
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000374:Aggression / Q000187:drug effects / Q000502:physiology / Q000523:psychology*; D014150:Antipsychotic Agents / Q000627:therapeutic use; D001521:Behavior Therapy / Q000379:methods; D017028:Caregivers / Q000523:psychology; D003704:Dementia / Q000188:drug therapy / Q000503:physiopathology / Q000523:psychology*; D006801:Humans; D010551:Personality; D011595:Psychomotor Agitation / Q000188:drug therapy / Q000503:physiopathology / Q000523:psychology*
chemical_list: D014150:Antipsychotic Agents