title: Induction of labour with vaginal prostaglandin tablet vs gel.
abstract: The objective of this study was to compare outcomes in women whose labour was induced with vaginal prostaglandin E2 tablets with those induced with prostaglandin gel. We compared outcomes of induction during two audits conducted in 2005 (PGE2 gel) and 2009 (PGE2 tablets). We found that there was no difference in induction rates; 21% in 2005 and 24% in 2009. The recommended dose of prostaglandin E2 was exceeded in 6% and 17% of women induced with gel and tablets, respectively (p=0.007). There was a difference in use of syntocinon to augment uterine contractions, 39% vs 58% for women induced with gel and tablets, respectively (p=0.001). There was no difference in overall operative delivery, 37% in gel and 38% in tablets. There was no difference in the proportion of women who had vaginal birth within 24 h; 50% vs 42% for gel and tablet, respectively (p=0.187). We conclude that compared to prostaglandin gel, women who received prostaglandin tablets were more likely to require syntocinon to augment contractions.
authors.affiliation: Department of Obstetrics and Gynaecology, Singleton Hospital, Swansea, UK. zainabmallhi@yahoo.co.uk
authors.forename: Z A
authors.initials: ZA
authors.lastname: Khan
authors.forename: B
authors.initials: B
authors.lastname: Abdul
authors.forename: F
authors.initials: F
authors.lastname: Majoko
mesh_terms: D000282:Administration, Intravaginal; D000328:Adult; D015232:Dinoprostone / Q000008:administration & dosage*; D005260:Female; D005782:Gels / Q000008:administration & dosage; D006801:Humans; D007751:Labor, Induced / Q000379:methods*; D010120:Oxytocics; D011247:Pregnancy; D011256:Pregnancy Outcome; D012189:Retrospective Studies; D013607:Tablets / Q000008:administration & dosage
chemical_list: D005782:Gels; D010120:Oxytocics; D013607:Tablets; D015232:Dinoprostone