title: Lowering the dose in head CT using adaptive statistical iterative reconstruction.
abstract: OBJECTIVE
  While CT has found wide use in medical practice, it is also a substantial source of radiation exposure and is associated with an increased lifetime risk of cancer. There is an urgent need for new approaches to reduce the radiation dose in CT. In this regard, ASIR is an alternative method to FBP. We assessed the effect of ASIR on dose reduction in adult head CT.
  
  
  METHODS
  We retrospectively evaluated a sample of 149 adult head CT examinations that were divided into 2 groups, STD and LD. We lowered the tube current and used ASIR in the LD group. SNR and CNR were analyzed. Dose parameters were recorded while subjective image noise, sharpness, diagnostic acceptability, and artifacts were graded. The Student t test, the Mann-Whitney U test, and κ statistics were used for statistical analyses.
  
  
  RESULTS
  We achieved a dose reduction of 31% in the LD group (STD, 2.3 ± 0.1 mSv; LD, 1.6 ± 0.1 mSv; P < .001). There was no significant difference in the noise measured in the air between the 2 comparison groups (P = .273). Noise in the CSF was higher in the STD group (P < .001), while the noise in the WM was higher in the LD group (P < .001). Differences in the CNR between groups were insignificant, but the STD group displayed better SNR values. There was no significant difference in the modal scores of diagnostic acceptability (P = .062) and the artifacts (P = .148) between the 2 groups. Better scores for subjective image noise (P < .001) and sharpness (P = .04) were observed in the STD group.
  
  
  CONCLUSIONS
  ASIR appears to be useful in reducing the dose in adult head CT examinations. While the effect of ASIR on noise reduction observed in the present study of head CT is less than that reported previously in abdomen and chest CT, these findings encourage further prospective studies in larger patient samples.
authors.affiliation: Department of Radiology, School of Medicine, Gazi University, Ankara, Turkey. koraykilic@yahoo.com
authors.forename: K
authors.initials: K
authors.lastname: Kilic
authors.forename: G
authors.initials: G
authors.lastname: Erbas
authors.forename: M
authors.initials: M
authors.lastname: Guryildirim
authors.forename: M
authors.initials: M
authors.lastname: Arac
authors.forename: E
authors.initials: E
authors.lastname: Ilgit
authors.forename: B
authors.initials: B
authors.lastname: Coskun
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000465:Algorithms; D016477:Artifacts; D001479:Basal Ganglia / Q000000981:diagnostic imaging; D003388:Cranial Fossa, Posterior / Q000000981:diagnostic imaging; D005260:Female; D006257:Head / Q000000981:diagnostic imaging*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009381:Neoplasms, Radiation-Induced / Q000453:epidemiology / Q000517:prevention & control*; D015588:Observer Variation; D011829:Radiation Dosage; D012189:Retrospective Studies; D012307:Risk Factors; D014057:Tomography, X-Ray Computed / Q000009:adverse effects / Q000379:methods* / Q000706:statistics & numerical data; D055815:Young Adult