title: Use of catalytic fluoride under neutral conditions for cleaving silicon-oxygen bonds.
abstract: This Article describes the development of conditions for cleaving silicon-oxygen bonds using catalytic quantities of fluoride at neutral pH in mixed organic-aqueous solutions that contain buffer. A variety of silicon protecting groups can be removed under these conditions, which show tolerance for acid- and base-sensitive groups. A modified procedure also is presented using catalytic fluoride in anhydrous dimethyl sulfoxide-methanol, which generates primarily volatile silicon byproducts.
authors.affiliation: Department of Chemistry, The Pennsylvania University, University Park, Pennsylvania 16802, USA.
authors.forename: Anthony M
authors.initials: AM
authors.lastname: DiLauro
authors.forename: Wanji
authors.initials: W
authors.lastname: Seo
authors.forename: Scott T
authors.initials: ST
authors.lastname: Phillips