title: Highly diastereo- and enantioselective NHC-catalyzed [3+2] annulation of enals and isatins.
abstract: The chiral N-heterocyclic carbene bearing a proximal hydroxy group derived from L-pyroglutamic acid was found to be an efficient catalyst for the [3+2] annulation of enals and isatins to give the corresponding spirocyclic oxindolo-γ-butyrolactones in good yield with good diastereo- and enantioselectivities.
authors.affiliation: Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China.
authors.forename: Li-Hui
authors.initials: LH
authors.lastname: Sun
authors.forename: Li-Tao
authors.initials: LT
authors.lastname: Shen
authors.forename: Song
authors.initials: S
authors.lastname: Ye