title: Absorbed dose assessment of cardiac and other tissues around the cardiovascular system in brachytherapy with 90Sr/90Y source by Monte Carlo simulation.
abstract: Cardiac disease is one of the most important causes of death in the world. Coronary artery stenosis is a very common cardiac disease. Intravascular brachytherapy (IVBT) is one of the radiotherapy methods which have been used recently in coronary artery radiation therapy for the treatment of restenosis. (90)Sr/(90)Y, a beta-emitting source, is a proper option for cardiovascular brachytherapy. In this research, a Monte Carlo simulation was done to calculate dosimetry parameters and effective equivalent doses to the heart and its surrounding tissues during IVBT. The results of this study were compared with the published experimental data and other simulations performed by different programs but with the same source of radiation. A very good agreement was found between results of this work and the published data. An assessment of the risk for cardiac and other sensitive soft tissues surrounding the treated vessel during (90)Sr/(90)Y IVBT was also performed in the study.
authors.affiliation: Department of Physics, Faculty of Science , University of Isfahan, 81746-73441 Isfahan,  Iran.
authors.forename: S
authors.initials: S
authors.lastname: Saghamanesh
authors.forename: A
authors.initials: A
authors.lastname: Karimian
authors.forename: M
authors.initials: M
authors.lastname: Abdi
mesh_terms: D000465:Algorithms; D001610:Beta Particles; D001918:Brachytherapy / Q000295:instrumentation* / Q000379:methods*; D003198:Computer Simulation; D023903:Coronary Restenosis / Q000532:radiotherapy*; D006321:Heart / Q000528:radiation effects; D006801:Humans; D009010:Monte Carlo Method; D019047:Phantoms, Imaging; D011874:Radiometry; D011879:Radiotherapy Dosage; D012062:Relative Biological Effectiveness; D013326:Strontium Radioisotopes / Q000627:therapeutic use*; D015021:Yttrium Radioisotopes / Q000627:therapeutic use*
chemical_list: D013326:Strontium Radioisotopes; D015021:Yttrium Radioisotopes