title: A comparison of brachytherapy techniques for partial breast irradiation.
abstract: Accelerated partial breast irradiation has emerged as an important treatment option for select patients with early-stage breast cancer. Numerous techniques for the delivery of accelerated partial breast irradiation have been developed involving both external beam and brachytherapy techniques. Brachytherapy techniques in general have the advantage of directly targeting the tumor bed and are not hampered by the requirement for large planning target volume margins needed with external beam techniques to account for uncertainties in targeting a very mobile organ, easily affected by patient and respiratory motion. We review established brachytherapy techniques and new emerging approaches. Technical considerations, available clinical data, advantages and shortcomings of each technique are reviewed.
authors.affiliation: Department of Radiation Oncology, Rhode Island Hospital, Brown University, Providence, RI 02903, USA. jhepel@lifespan.org
authors.forename: Jaroslaw T
authors.initials: JT
authors.lastname: Hepel
authors.forename: David E
authors.initials: DE
authors.lastname: Wazer
mesh_terms: D000367:Age Factors; D001918:Brachytherapy / Q000295:instrumentation / Q000379:methods*; D001943:Breast Neoplasms / Q000473:pathology / Q000532:radiotherapy*; D002986:Clinical Trials as Topic; D005260:Female; D006801:Humans; D011879:Radiotherapy Dosage