title: Circulating strains of human respiratory syncytial virus in central and south America.
abstract: Human respiratory syncytial virus (HRSV) is a major cause of viral lower respiratory tract infections among infants and young children. HRSV strains vary genetically and antigenically and have been classified into two broad subgroups, A and B (HRSV-A and HRSV-B, respectively). To date, little is known about the circulating strains of HRSV in Latin America. We have evaluated the genetic diversity of 96 HRSV strains by sequencing a variable region of the G protein gene of isolates collected from 2007 to 2009 in Central and South America. Our results show the presence of the two antigenic subgroups of HRSV during this period with the majority belonging to the genotype HRSV-A2.
authors.affiliation: United States Naval Medical Research Unit 6, Lima, Peru.
authors.forename: Merly
authors.initials: M
authors.lastname: Sovero
authors.forename: Josefina
authors.initials: J
authors.lastname: Garcia
authors.forename: Tadeusz
authors.initials: T
authors.lastname: Kochel
authors.forename: V Alberto
authors.initials: VA
authors.lastname: Laguna-Torres
authors.forename: Jorge
authors.initials: J
authors.lastname: Gomez
authors.forename: Wilson
authors.initials: W
authors.lastname: Chicaiza
authors.forename: Melvin
authors.initials: M
authors.lastname: Barrantes
authors.forename: Felix
authors.initials: F
authors.lastname: Sanchez
authors.forename: Mirna
authors.initials: M
authors.lastname: Jimenez
authors.forename: Guillermo
authors.initials: G
authors.lastname: Comach
authors.forename: Ivette Lorenzana
authors.initials: IL
authors.lastname: de Rivera
authors.forename: Ana E
authors.initials: AE
authors.lastname: Arango
authors.forename: Roberto
authors.initials: R
authors.lastname: Agudo
authors.forename: Eric S
authors.initials: ES
authors.lastname: Halsey
mesh_terms: D000818:Animals; D001483:Base Sequence; D002460:Cell Line; D002489:Central America; D017931:DNA Primers; D006801:Humans; D010802:Phylogeny; D012136:Respiratory Syncytial Viruses / Q000737:chemistry / Q000302:isolation & purification*; D020133:Reverse Transcriptase Polymerase Chain Reaction; D013020:South America
chemical_list: D017931:DNA Primers