title: [Post-marketing surveillance systems for psychoactive prescription drug abuse].
abstract: Drugs affecting the central nervous system form a unique group of products for surveillance because they could be misused, abused or diverted. Considering the characteristics of this behaviour that is often concealed, specific post-marketing surveillance systems have been developed to monitor abuse of prescription drugs in some countries. The purpose of this review is to list and to describe post-marketing surveillance systems, according their methodology, in France and in foreign countries. These programs are based on adverse effect notifications, medical or legal consequences of abuse, general or specific population-based survey, professional networks or medication databases. Some programs use simultaneously several information sources. In conclusion, the multifaceted nature, the diversity and the inventiveness of post-marketing surveillance systems reflects the complexity of the abuse issue.
authors.affiliation: Clinique de Pharmacologie, CHU Timone, Marseille, France.
authors.forename: Sandra
authors.initials: S
authors.lastname: Nordmann
authors.forename: Elisabeth
authors.initials: E
authors.lastname: Frauger
authors.forename: Vanessa
authors.initials: V
authors.lastname: Pauly
authors.forename: Frank
authors.initials: F
authors.lastname: Rouby
authors.forename: Michel
authors.initials: M
authors.lastname: Mallaret
authors.forename: Joëlle
authors.initials: J
authors.lastname: Micallef
authors.forename: Xavier
authors.initials: X
authors.lastname: Thirion
mesh_terms: D005602:France; D006801:Humans; D010361:Patients; D010820:Physicians; D011358:Product Surveillance, Postmarketing / Q000379:methods*; D011619:Psychotropic Drugs / Q000627:therapeutic use*; D019966:Substance-Related Disorders / Q000517:prevention & control
chemical_list: D011619:Psychotropic Drugs