title: New antioxidant bibenzyl derivative and isoflavonoid from the Tunisian Salsola tetrandra Folsk.
abstract: Two new phytochemical compounds, Tetranins A and B, 1-(3,5'-dihydroxy-4'-méthoxyphenyl)-2-phenylethanol 1 and 5,2'-dihydroxy-5'-methoxy-6,7-methylenedioxy-isoflavone 2, were isolated from the EtOAc extract of Salsola tetrandra roots. They exhibited a significant antioxidant effect in 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical and 2,2'-azinobis (3-ethylbenzothiazoline-6-sulphonic acid (ABTS) assays. Their structures were elucidated by extensive spectroscopic methods including 1-D-((1)H and (13)C) and 2-D-NMR experiments (CHcorr, HMBC, (1)H-(1)H COSY and NOESY) as well as high-resolution ES-MS and they were found to be quite active as antioxidants in the DPPH and ABTS assays.
authors.affiliation: Department of Chemistry, Laboratory of Natural Products, Faculty of Sciences, University of Monastir, Monastir 5000, Tunisia.
authors.forename: Ahlem
authors.initials: A
authors.lastname: Beyaoui
authors.forename: Atef
authors.initials: A
authors.lastname: Chaari
authors.forename: Hatem
authors.initials: H
authors.lastname: Ghouila
authors.forename: M'hamed
authors.initials: M
authors.lastname: Ali Hamza
authors.forename: Hichem
authors.initials: H
authors.lastname: Ben Jannet
mesh_terms: D000975:Antioxidants / Q000302:isolation & purification* / Q000494:pharmacology; D005419:Flavonoids / Q000302:isolation & purification* / Q000494:pharmacology; D016166:Free Radical Scavengers / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D010936:Plant Extracts / Q000302:isolation & purification* / Q000494:pharmacology; D031248:Salsola / Q000737:chemistry*; D021241:Spectrometry, Mass, Electrospray Ionization; D013055:Spectrophotometry, Infrared
chemical_list: D000975:Antioxidants; D005419:Flavonoids; D016166:Free Radical Scavengers; D010936:Plant Extracts