title: SEOM clinical guidelines for diagnosis and treatment of testicular seminoma (2010).
abstract: Testicular cancer represents the most common malignancy in males aged 15-34 years. Nearly 40% of cases correspond to seminomas and three quarters of them are diagnosed with stage I disease. After orchiectomy, clinical staging should include serial tumour marker assays (alphafetoprotein must be negative), abdominal CT scan and chest X-ray films. Patients with stage I disease can be followedup (active surveillance) or receive adjuvant carboplatin chemotherapy (those with rete testis invasion or non-compliant with follow-up). More advanced disease (stage II and III) and patients with extragonadal seminomas should receive chemotherapy (3-4 courses of BEP) according to IGCCCG risk classification. Residual lesions must be managed by surveillance if they are smaller than 3 cm, while those larger than 3 cm should be evaluated by means of PET. Surgery is only recommended in PET-positive lesions.
authors.affiliation: Servicio de Oncología Médica, Hospital Universitario La Fe, Valencia, Spain. japariciou@seom.org
authors.forename: Jorge
authors.initials: J
authors.lastname: Aparicio
authors.forename: Javier
authors.initials: J
authors.lastname: Sastre
authors.forename: José Ramón
authors.initials: JR
authors.lastname: Germà
authors.forename: Dolores
authors.initials: D
authors.lastname: Isla
mesh_terms: D000293:Adolescent; D000328:Adult; D006801:Humans; D008297:Male; D008495:Medical Oncology / Q000379:methods*; D009367:Neoplasm Staging / Q000379:methods; D018239:Seminoma / Q000628:therapy*; D012955:Societies, Medical; D013736:Testicular Neoplasms / Q000628:therapy*; D014057:Tomography, X-Ray Computed / Q000379:methods; D016896:Treatment Outcome; D014965:X-Rays