title: [Non-surgical treatment for nonresectable advanced hepatic alveolar echinococcosis].
abstract: OBJECTIVE
  To investigate the therapeutic methods of nonresectable advanced hepatic alveolar echinococcosis.
  
  
  METHODS
  A retrospective study was carried out to analyze 25 cases of nonresectable advanced hepatic alveolar echinococcosis in the Fourth Hospital of PLA from 2006 to 2009.
  
  
  RESULTS
  There were 18 male and 7 female patients with a mean age of 41 years. Twelve cases were treated with albendazole alone. Eleven patients were treated with albendazole combined with percutaneous puncture. Two cases were treated with albendazole combined with other intervention. A course of albendazole administration lasted 2 weeks with a dose of 15-20 mg/(kg x d) for 3 course in general. Eighteen patients were followed up for 1-4 years. In albendazole group, 2 cases were effective and 7 cases were symptom-improved. Five patients got improved and 2 cases showed effective in albendazole combined with percutaneous puncture group. Two cases of albendazole combined with intervention group showed no efficacy.
  
  
  CONCLUSIONS
  Long-term use of albendazole is the main treatment for nonresectable advanced hepatic alveolar echinococcosis.
authors.affiliation: Department of Surgery, The Fourth Hospital of PLA, Xining 810007, China. Tangqunke@hotmail.com
authors.forename: Qun-ke
authors.initials: QK
authors.lastname: Tang
authors.forename: Ying
authors.initials: Y
authors.lastname: Zhang
authors.forename: Yong-shou
authors.initials: YS
authors.lastname: Li
authors.forename: Chun-ping
authors.initials: CP
authors.lastname: Yuan
authors.forename: Dong-tian
authors.initials: DT
authors.lastname: Zhang
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D015766:Albendazole / Q000627:therapeutic use*; D004444:Echinococcosis, Hepatic / Q000628:therapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D015766:Albendazole