title: Systolic blood pressure control after participation in a hypertension intervention study.
abstract: OBJECTIVE
  To evaluate whether systolic blood pressure (SBP) control is maintained following participation in a multimodal hypertension intervention.
  
  
  METHODS
  This was a retrospective cohort of patients completing the Improving Blood Pressure in Colorado study, a randomized trial comparing a multimodal intervention with usual care for patients who had uncontrolled hypertension. Chart review assessed the first SBP measurement recorded as part of routine care after the study ended. Among patients who had controlled SBP at the final study visit, the proportions who had uncontrolled SBP during follow-up were compared for the intervention and usual care (UC) groups. Kaplan-Meier estimates assessed time to uncontrolled SBP by treatment arm.
  
  
  RESULTS
  Of 283 patients completing the Improving Blood Pressure in Colorado study, 51.5% in the intervention and 46.9% in the UC group had controlled SBP at the final study visit. Of patients with controlled SBP, 37.0% and 46.4% of patients in the intervention and UC groups, respectively, had uncontrolled SBP at their initial measurement during follow-up (P = .32). There was no difference in median time to uncontrolled SBP (126 vs 114 days for the intervention and UC groups, respectively; P = .47).
  
  
  CONCLUSIONS
  SBP control was not maintained in a significant proportion of patients in both groups following hypertension study participation. These findings suggest the need for interventions to focus on longer-term BP control in contrast to the short duration of most hypertension intervention trials.
authors.affiliation: Denver, CO 80220, USA. Lesley.welch@va.gov
authors.forename: Lesley K
authors.initials: LK
authors.lastname: Welch
authors.forename: Kari L
authors.initials: KL
authors.lastname: Olson
authors.forename: Karen E
authors.initials: KE
authors.lastname: Snow
authors.forename: Lauren
authors.initials: L
authors.lastname: Pointer
authors.forename: Anne
authors.initials: A
authors.lastname: Lambert-Kerzner
authors.forename: Edward P
authors.initials: EP
authors.lastname: Havranek
authors.forename: David J
authors.initials: DJ
authors.lastname: Magid
authors.forename: P Michael
authors.initials: PM
authors.lastname: Ho
mesh_terms: D000328:Adult; D000959:Antihypertensive Agents / Q000627:therapeutic use*; D001794:Blood Pressure / Q000187:drug effects; D015331:Cohort Studies; D003120:Colorado; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006973:Hypertension / Q000188:drug therapy / Q000503:physiopathology / Q000628:therapy*; D008297:Male; D011446:Prospective Studies; D012189:Retrospective Studies
chemical_list: D000959:Antihypertensive Agents