title: Techniques for functional and structural modeling of nitrogenase.
abstract: Synthetic compounds play an important role in developing our understanding of nitrogenase enzymes, and over the years, a multitude of new metal-containing compounds have been created using nitrogenase as an inspiration. The techniques for handling coordination compounds in organic solvents are different than those commonly encountered in a biochemistry or molecular biology laboratory. This chapter describes the precautions that are essential for successful synthesis of air- and moisture-sensitive synthetic compounds and gives details of the synthesis of some coordinatively unsaturated iron-dinitrogen and iron-sulfide compounds of interest in nitrogenase research.
authors.affiliation: Department of Chemistry, University of Rochester, 14618 Rochester, NY, USA. Holland@chem.rochester.edu
authors.forename: Patrick L
authors.initials: PL
authors.lastname: Holland
mesh_terms: D008958:Models, Molecular; D015394:Molecular Structure; D009591:Nitrogenase / Q000737:chemistry*
chemical_list: D009591:Nitrogenase