title: Incidence, risk factors and ERCP outcome for biliary complications after cadaveric OLT.
abstract: OBJECTIVE
  Biliary complications (BC) occur in up to 39.5% of patients after orthotopic liver transplantation (OLT), being an important source of post-transplant morbidity. The aim is to evaluate the incidence of BC after OLT, associated risk factors and outcome after endoscopic treatment.
  
  
  METHODS
  A retrospective case series between June 2005 and December 2008, including 195 patients that underwent 216 OLT from deceased donors. Thirty-one patients (14.3%) presented at least 1 BC, anastomotic stricture being the most frequent (83.8%). Non-anastomotic stricture was present in 1 (3.2%) and anastomotic fistula in 1. One patient presented anastomotic disconnection at ERCP.
  
  
  RESULTS
  BC occurred 94.6 (7-487) days after OLT. Twenty-seven patients underwent endoscopic treatment, on average 2.6 ERCPs were performed per patient. Global endoscopic treatment success rate was 77.3%; being 73.7% for stenosis and 100% (3/3) for anastomotic fistula with stenosis. Recurrence of biliary stricture was observed in 3 patients, all referred to endoscopic re-treatment. ERCP complications: 2 (2.8%) stent migrations, 1 (1.4%) early stent occlusion, 1 (1.4%) respiratory distress and 1(1.4%) severe acute pancreatitis and death. There was no correlation between studied risk factors and BC's occurrence.
  
  
  CONCLUSIONS
  ERCP was effective for the treatment of BC after OLT. Studied risk factors had no correlation with BC.
authors.affiliation: Department of Endoscopy, Hospital Israelita Albert Einstein, São Paulo, Brazil. fernandaprata@terra.com.br
authors.forename: Fernanda Prata
authors.initials: FP
authors.lastname: Martins
authors.forename: Gustavo Andrade
authors.initials: GA
authors.lastname: De Paulo
authors.forename: Raquel Dilgerian
authors.initials: RD
authors.lastname: Conceição
authors.forename: Maria Paula
authors.initials: MP
authors.lastname: Zurstrassen
authors.forename: Tadeu
authors.initials: T
authors.lastname: Thomé
authors.forename: Ben-Hur
authors.initials: BH
authors.lastname: Ferraz-Neto
authors.forename: Angelo Paulo
authors.initials: AP
authors.lastname: Ferrari
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001660:Biliary Tract Diseases / Q000453:epidemiology* / Q000209:etiology; D002102:Cadaver; D002648:Child; D002760:Cholangiopancreatography, Endoscopic Retrograde / Q000009:adverse effects*; D005260:Female; D006801:Humans; D015994:Incidence; D016031:Liver Transplantation / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000453:epidemiology* / Q000209:etiology; D012189:Retrospective Studies; D012307:Risk Factors