title: Renal disease in an urban HIV population in the era prior and following the introduction of highly active antiretroviral therapy.
abstract: Renal disease related to human immunodeficiency virus (HIV) has been a past and present burden on the HIV positive community, both in the United States and worldwide. Previously, focus has been on the impact of HIV-associated nephropathy (HIVAN) on the black population. This paper presents a large renal biopsy series of 108 HIV patients from an urban setting with early renal dysfunction. The purpose of the paper is to highlight clinical characteristics and epidemiological changes in HIV-related renal disease between 2 distinct time periods: pre- and postintroduction of highly active antiretroviral therapy. Our data show a persistence of HIVAN in the black HIV US population and, in addition, an increase in other renal diseases in that population. These findings are discussed in regard to current and future HIV renal disease management.
authors.affiliation: Southern Manhattan Hemodialysis Center, 510-526 Avenue of the Americas, SC Floor, New York, NY 10011, USA. andrew.bohmart@gmail.com
authors.forename: Andrew
authors.initials: A
authors.lastname: Bohmart
authors.forename: Godfrey
authors.initials: G
authors.lastname: Burns
mesh_terms: D016263:AIDS-Associated Nephropathy / Q000188:drug therapy* / Q000453:epidemiology* / Q000473:pathology* / Q000503:physiopathology / Q000821:virology; D000328:Adult; D019380:Anti-HIV Agents / Q000627:therapeutic use; D023241:Antiretroviral Therapy, Highly Active / Q000706:statistics & numerical data / Q000639:trends*; D044963:Biopsy, Fine-Needle; D005260:Female; D006678:HIV / Q000187:drug effects; D006679:HIV Seropositivity / Q000453:epidemiology / Q000208:ethnology; D019456:Health Transition; D006801:Humans; D007668:Kidney / Q000473:pathology* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D010818:Practice Patterns, Physicians' / Q000639:trends*; D015995:Prevalence; D012189:Retrospective Studies; D014481:United States / Q000453:epidemiology / Q000208:ethnology; D014505:Urban Population / Q000706:statistics & numerical data / Q000639:trends
chemical_list: D019380:Anti-HIV Agents