title: Guidelines of care for the management of primary cutaneous melanoma. American Academy of Dermatology.
abstract: The incidence of primary cutaneous melanoma has been increasing dramatically for several decades. Melanoma accounts for the majority of skin cancer-related deaths, but treatment is nearly always curative with early detection of disease. In this update of the guidelines of care, we will discuss the treatment of patients with primary cutaneous melanoma. We will discuss biopsy techniques of a lesion clinically suspicious for melanoma and offer recommendations for the histopathologic interpretation of cutaneous melanoma. We will offer recommendations for the use of laboratory and imaging tests in the initial workup of patients with newly diagnosed melanoma and for follow-up of asymptomatic patients. With regard to treatment of primary cutaneous melanoma, we will provide recommendations for surgical margins and briefly discuss nonsurgical treatments. Finally, we will discuss the value and limitations of sentinel lymph node biopsy and offer recommendations for its use in patients with primary cutaneous melanoma.
authors.affiliation: Department of Dermatology, University of Michigan Health System and Comprehensive Cancer Center, Ann Arbor, Michigan, USA.
authors.forename: Christopher K
authors.initials: CK
authors.lastname: Bichakjian
authors.forename: Allan C
authors.initials: AC
authors.lastname: Halpern
authors.forename: Timothy M
authors.initials: TM
authors.lastname: Johnson
authors.forename: Antoinette
authors.initials: A
authors.lastname: Foote Hood
authors.forename: James M
authors.initials: JM
authors.lastname: Grichnik
authors.forename: Susan M
authors.initials: SM
authors.lastname: Swetter
authors.forename: Hensin
authors.initials: H
authors.lastname: Tsao
authors.forename: Victoria Holloway
authors.initials: VH
authors.lastname: Barbosa
authors.forename: Tsu-Yi
authors.initials: TY
authors.lastname: Chuang
authors.forename: Madeleine
authors.initials: M
authors.lastname: Duvic
authors.forename: Vincent C
authors.initials: VC
authors.lastname: Ho
authors.forename: Arthur J
authors.initials: AJ
authors.lastname: Sober
authors.forename: Karl R
authors.initials: KR
authors.lastname: Beutner
authors.forename: Reva
authors.initials: R
authors.lastname: Bhushan
authors.forename: Wendy
authors.initials: W
authors.lastname: Smith Begolka
mesh_terms: D000634:Aminoquinolines / Q000627:therapeutic use; D000970:Antineoplastic Agents / Q000627:therapeutic use; D058070:Asymptomatic Diseases; D017679:Cryotherapy; D003952:Diagnostic Imaging; D019317:Evidence-Based Medicine; D005500:Follow-Up Studies; D006801:Humans; D018327:Hutchinson's Melanotic Freckle / Q000188:drug therapy / Q000532:radiotherapy; D000077271:Imiquimod; D008207:Lymphatic Metastasis; D008545:Melanoma / Q000175:diagnosis / Q000473:pathology / Q000556:secondary / Q000601:surgery / Q000628:therapy*; D009260:Nail Diseases / Q000175:diagnosis / Q000628:therapy; D060787:Neoplasm Grading / Q000592:standards; D009367:Neoplasm Staging / Q000592:standards; D021701:Sentinel Lymph Node Biopsy; D012878:Skin Neoplasms / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery / Q000628:therapy*
chemical_list: D000634:Aminoquinolines; D000970:Antineoplastic Agents; D000077271:Imiquimod