title: Improved premenstrual syndrome symptoms after NovaSure endometrial ablation.
abstract: OBJECTIVE
  To evaluate the change in premenstrual syndrome (PMS) symptoms in women with heavy periods who underwent endometrial ablation.
  
  
  METHODS
  The study used a prospective, single-arm cohort of adult women who were to undergo NovaSure endometrial ablation for heavy menses who also reported symptoms of PMS. A brief baseline survey was done to evaluate menstrual bleeding and baseline PMS symptoms, and two 30-day prospective validated measures of PMS were used. Follow-up surveys were sent at 4 to 6 months and included both the brief survey questions and the validated measures of PMS (Canadian Task Force classification II-3).
  
  
  RESULTS
  Thirty-six women with heavy periods who were to undergo endometrial ablation had PMS symptoms and completed all surveys at baseline and follow-up. The mean age was 41.4 years, with a mean body mass index of 26.7. Most (27/36, 75%) had failed hormonal management. All measures of PMS showed significant improvement after endometrial ablation. Self-rating of PMS symptoms on a scale of 0 (none) to 10 (severe) improved from a baseline of 7.4 to a follow-up rating of 3.2 (p <.05). The vast majority of women (35/36, 97%) reported improvement in PMS after undergoing endometrial ablation. Both validated measures of PMS, Daily Symptoms Report and Daily Record of Severity of Symptoms, showed statistically significant improvement in PMS symptoms.
  
  
  CONCLUSIONS
  Women with heavy menses and associated PMS symptoms who undergo NovaSure endometrial ablation showed improvement in PMS symptoms, as well as reduced menstrual bleeding.
authors.affiliation: Carolina Women's Research and Wellness Center, Durham, NC 27713, USA. andrealukes@cwrwc.com
authors.forename: Andrea S
authors.initials: AS
authors.lastname: Lukes
authors.forename: Ryan J
authors.initials: RJ
authors.lastname: McBride
authors.forename: Amy H
authors.initials: AH
authors.lastname: Herring
authors.forename: Michael
authors.initials: M
authors.lastname: Fried
authors.forename: Atiya
authors.initials: A
authors.lastname: Sherwani
authors.forename: Diana
authors.initials: D
authors.lastname: Dell
mesh_terms: D000328:Adult; D055356:Endometrial Ablation Techniques; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008595:Menorrhagia / Q000601:surgery*; D008875:Middle Aged; D011293:Premenstrual Syndrome / Q000601:surgery*; D011446:Prospective Studies; D012720:Severity of Illness Index; D016896:Treatment Outcome