title: [The study of human rhinovirus in infants with lower respiratory tract infections].
abstract: OBJECTIVE
  We want to explore the harm degree of human rhinovirus in infants in Beijing area.
  
  
  METHODS
  From May 2008 to September 2009, 240 nasopharyngeal aspirates were collected from the children and infants who were hospitalized and with lower respiratory tract infections. These specimens were screened for HRV by real-time reverse transcription PCR (RT-PCR) and statistically analysised.
  
  
  RESULTS
  In all of 240 hospitalized children, 208 cases were admission diagnosis of pneumonia, accounting for 86.67% (208/240), no deaths, the ratio of male and female patients was 1.93 : 1, and the collected samples reached to a maximum number in February 2009. Real-time PCR used to detect human rhinovirus, positive samples number is 71, positive rate is 29.58% (71/240), and the main symptoms and clinical diagnosis was pneumonia. Most cases were less than 2 years old, making up 81.69% (58/71), amony them, 13 months-18 months age and > or = 24 months groups have the highest incidence rates, the incidence rate is 33.33%.
  
  
  CONCLUSIONS
  Human rhinovirus happened in spring and winter seasons, especially the infants who were under 2 years are the main infection groups, the important symptoms are lower respiratory infections such as pneumonia, bronchitis and bronchiolitis et al. Human rhinovirus is seasonal and contagious, spreads fast, so protective measures in hospitals should be prepared to avoid cross-infection.
authors.affiliation: Department of Neurobiology, Taishan Medical College, Taian 271000, China.
authors.forename: Huan-huan
authors.initials: HH
authors.lastname: Wang
authors.forename: Nai-ying
authors.initials: NY
authors.lastname: Mao
authors.forename: Song-tao
authors.initials: ST
authors.lastname: Xu
authors.forename: Liu-ying
authors.initials: LY
authors.lastname: Tang
authors.forename: Hui-ling
authors.initials: HL
authors.lastname: Wang
authors.forename: Zheng-dei
authors.initials: ZD
authors.lastname: Xie
authors.forename: Zeng-xian
authors.initials: ZX
authors.lastname: Wang
authors.forename: Wen-bo
authors.initials: WB
authors.lastname: Xu
mesh_terms: D002648:Child; D002675:Child, Preschool; D002681:China; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D010850:Picornaviridae Infections / Q000821:virology*; D012141:Respiratory Tract Infections / Q000821:virology*; D012229:Rhinovirus / Q000235:genetics / Q000302:isolation & purification*; D012621:Seasons