title: Gold(I)-catalyzed tandem cyclization-selective migration reaction of 1,3-dien-5-ynes: regioselective synthesis of highly substituted benzenes.
abstract: Highly substituted benzene derivatives have been easily prepared in a regioselective way from readily available 1,3-hexadien-5-ynes through a gold(I)-catalyzed tandem reaction. The process involves an initial cyclization followed by a selective Wagner-Meerwein shift in which the migration preference seems to be determined by the ability to stabilize a positive charge.
authors.affiliation: Área de Química Orgánica, Departamento de Química, Facultad de Ciencias, Universidad de Burgos, Pza. Misael Bañuelos s/n, 09001-Burgos, Spain.
authors.forename: Patricia
authors.initials: P
authors.lastname: García-García
authors.forename: Alberto
authors.initials: A
authors.lastname: Martínez
authors.forename: Ana M
authors.initials: AM
authors.lastname: Sanjuán
authors.forename: Manuel A
authors.initials: MA
authors.lastname: Fernández-Rodríguez
authors.forename: Roberto
authors.initials: R
authors.lastname: Sanz
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D001555:Benzene Derivatives / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D003500:Cyclization; D006046:Gold / Q000737:chemistry*; D015394:Molecular Structure; D050607:Organogold Compounds / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000480:Alkynes; D001555:Benzene Derivatives; D050607:Organogold Compounds; D006046:Gold