title: Antimicrobial activity of Hedeoma drummondii against opportunistic pathogens.
abstract: Hedeoma drummondii is a medicinal plant with diverse properties; however, validations of its medicinal uses are scarce. To evaluate its antimicrobial properties H. drummondii, was tested against opportunistic pathogens of medical importance. Antimicrobial tests were performed by the microdilution method in order to determine the Minimal Inhibitory Concentration (MIC) for each extract. Extracts of this plant showed relevant antimicrobial activity, results revealed that the hexanic extract has stronger activity and broader spectrum compared to acetone and methanol extracts. The activity of hexanic extract may be attributed mainly to the presence of the monoterpenes pulegone and menthol. In conclusion, the hexanic extract possess relevant antibacterial properties which suggests that H. drummondii have bioactive principles; these new data provide scientific support for the use of this plant in traditional medicine, particularly for gastrointestinal diseases.
authors.affiliation: Department of Chemistry, Faculty of Biological Sciences, Autonomous University of Nuevo Leon, San Nicolas de los Garza, Mexico.
authors.forename: E
authors.initials: E
authors.lastname: Viveros-Valdez
authors.forename: C
authors.initials: C
authors.lastname: Rivas-Morales
authors.forename: A
authors.initials: A
authors.lastname: Oranday-Cardenas
authors.forename: M J
authors.initials: MJ
authors.lastname: Verde-Star
authors.forename: P
authors.initials: P
authors.lastname: Carranza-Rosales
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects; D000081005:Cyclohexane Monoterpenes; D031336:Hedeoma / Q000737:chemistry*; D006586:Hexanes / Q000737:chemistry; D008826:Microbial Sensitivity Tests; D039821:Monoterpenes / Q000494:pharmacology; D010936:Plant Extracts / Q000494:pharmacology*
chemical_list: D000900:Anti-Bacterial Agents; D000081005:Cyclohexane Monoterpenes; D006586:Hexanes; D039821:Monoterpenes; D010936:Plant Extracts; C039648:pulegone