title: An anatomical study of the myelination of human laryngeal nerves.
abstract: OBJECTIVE
  To determine the differences in myelination between the human recurrent laryngeal nerve and superior laryngeal nerve.
  
  
  METHODS
  Fifteen confirmed laryngeal nerve specimens were harvested from five cadavers. Cross-sections were examined under a photomicroscope and morphometric analysis performed.
  
  
  RESULTS
  There was a significantly greater number of myelinated fibres than unmyelinated fibres, in both the recurrent laryngeal nerve (p = 0.018) and the superior laryngeal nerve (p = 0.012). There was a significantly greater number of myelinated fibres in the superior laryngeal nerve, compared with the recurrent laryngeal nerve (p = 0.028). However, there was no significant difference in the number of unmyelinated fibres, comparing the two nerves (p = 0.116).
  
  
  CONCLUSIONS
  These findings support those of previous studies, and provide further evidence against the historical plexus theory of laryngeal nerve morphology. The differences in the degree of myelination, both within and between the human laryngeal nerves, may have clinical consequence regarding recovery of function following nerve injury.
authors.affiliation: ENT Department, Royal Sussex County Hospital, Brighton, UK. JCFleming@doctors.net.uk
authors.forename: J C
authors.initials: JC
authors.lastname: Fleming
authors.forename: N
authors.initials: N
authors.lastname: Gibbins
authors.forename: P J
authors.initials: PJ
authors.lastname: Ingram
authors.forename: M
authors.initials: M
authors.lastname: Harries
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002102:Cadaver; D006801:Humans; D007823:Laryngeal Nerves / Q000033:anatomy & histology*; D008875:Middle Aged; D009186:Myelin Sheath / Q000502:physiology; D009413:Nerve Fibers, Myelinated; D036421:Nerve Fibers, Unmyelinated; D009445:Neuroanatomy; D012009:Recurrent Laryngeal Nerve / Q000033:anatomy & histology