title: Full-term pregnancy and vaginal delivery after treatment for non-Hodgkin's lymphoma of the cervix and lower uterine segment: a case report.
abstract: BACKGROUND
  Primary gynaecologic non-Hodgkin's lymphomas are rare. We present a case of primary large B-cell lymphoma localized to the lower uterine segment and endocervical stroma that was successfully treated with chemotherapy and immunotherapy. Treatment was followed by a disease-free interval and successful term vaginal delivery.
  
  
  METHODS
  A 21-year-old nulliparous woman presented with dysfunctional uterine bleeding. Radiologic assessment of a posterior lower uterine segment mass and pathologic evaluation of cervical biopsies demonstrated diffuse large B-cell lymphoma involving the endocervical stroma. The patient was treated with chemotherapy and immunotherapy. She had a normal, uncomplicated full-term pregnancy and spontaneous vaginal delivery six years after treatment.
  
  
  CONCLUSIONS
  Aggressive diagnosis and treatment of primary non-Hodgkin's lymphomas of the cervix do not preclude the possibility of a successful pregnancy and term vaginal delivery.
authors.affiliation: Department of Obstetrics and Gynecology, Lankenau Hospital, Wynnewood PA.
authors.forename: Mehdi
authors.initials: M
authors.lastname: Parva
authors.affiliation: Jefferson Medical College, Thomas Jefferson University, Philadelphia PA.
authors.forename: Kathleen
authors.initials: K
authors.lastname: Lamb
authors.affiliation: Department of Hematology and Oncology, Lankenau Hospital, Wynnewood PA.
authors.forename: Deric C
authors.initials: DC
authors.lastname: Savior
authors.affiliation: Department of Hematology and Oncology, Lankenau Hospital, Wynnewood PA.
authors.forename: Paul
authors.initials: P
authors.lastname: Gilman
authors.affiliation: Department of Obstetrics and Gynecology, Lankenau Hospital, Wynnewood PA; Jefferson Medical College, Thomas Jefferson University, Philadelphia PA.
authors.forename: Michael
authors.initials: M
authors.lastname: Belden
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D036861:Delivery, Obstetric; D005260:Female; D059247:Fertility Preservation; D006801:Humans; D007167:Immunotherapy; D016403:Lymphoma, Large B-Cell, Diffuse / Q000175:diagnosis / Q000628:therapy*; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic; D011256:Pregnancy Outcome; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis / Q000628:therapy*; D014594:Uterine Neoplasms / Q000175:diagnosis / Q000628:therapy*