title: Change in transfusion practice in massively bleeding patients.
abstract: This retrospective study evaluates changes in transfusion practice and modified blood product utilisation that occurred over the course of eleven years in patients receiving massive transfusion. The mean number of fresh frozen plasma units transfused increased from 9.0 ± 7.9 in 1998 to 11.3 ± 6.7 in 2008 (p=0.03). The mean number of platelet units increased from 1.9 ± 1.3 in 1998 to 2.6 ± 1.7 in 2008 (p=0.02). The proportion of cryoprecipitate increased from 0.03 ± 0.19 in 1998 to 1.3 ± 1.6 in 2008 (p=0.001). Along with these changes was a trend toward decreased mortality (p=0.05).
authors.affiliation: Flinders Medical Centre, Transfusion Services, Flinders Medical Centre, Flinders Drive, Bedford Park, SA 5042, Australia. Romi.Sinha@health.sa.gov.au
authors.forename: Romi
authors.initials: R
authors.lastname: Sinha
authors.forename: David
authors.initials: D
authors.lastname: Roxby
mesh_terms: D000368:Aged; D001803:Blood Transfusion / Q000379:methods* / Q000639:trends; D005260:Female; D006470:Hemorrhage / Q000097:blood / Q000628:therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies