title: Conservative management of placenta increta: case report and literature review.
abstract: Placenta increta, a rare complication of pregnancy, is associated with significant postpartum hemorrhage often requiring emergency hysterectomy. We report a case of conservative management, with a combination of parenteral methotrexate, serial ultrasound and β-hCG assessment. Serum β-hCG levels were undetectable after 8 weeks of therapy. A scan at 6 months showed complete involution of the uterus. Review of the literature discussing the diagnostic tools, clinical features, management and outcome of pregnancies with placenta increta.
authors.affiliation: Department of Gynecological Oncology, School of Medicine, Tehran University of Medical Sciences, Mirza Koochak-Khan Hospital, Tehran, Iran. Fariba_Yarandi@Yahoo.com
authors.forename: Fariba
authors.initials: F
authors.lastname: Yarandi
authors.forename: Zahra
authors.initials: Z
authors.lastname: Eftekhar
authors.forename: Hadi
authors.initials: H
authors.lastname: Shojaei
authors.forename: Fatemeh
authors.initials: F
authors.lastname: Rahimi-Sharbaf
authors.forename: Fatemeh
authors.initials: F
authors.lastname: Baradaran
mesh_terms: D000020:Abortifacient Agents, Nonsteroidal / Q000008:administration & dosage*; D000328:Adult; D015415:Biomarkers / Q000097:blood; D018997:Chorionic Gonadotropin, beta Subunit, Human / Q000097:blood; D005260:Female; D006801:Humans; D007273:Injections, Intramuscular; D008727:Methotrexate / Q000008:administration & dosage*; D010921:Placenta Accreta / Q000097:blood / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000188:drug therapy*; D011247:Pregnancy; D050497:Stillbirth; D013997:Time Factors; D016896:Treatment Outcome; D018615:Ultrasonography, Doppler, Color
chemical_list: D000020:Abortifacient Agents, Nonsteroidal; D015415:Biomarkers; D018997:Chorionic Gonadotropin, beta Subunit, Human; D008727:Methotrexate