title: [Forensic medical diagnostics of chronic alcoholic intoxication based on histological changes in the soft tissues of oral cavity and salivary glands].
abstract: Histological studies of oral cavity mucosa and salivary glands in subjects with chronic alcoholic intoxication revealed changes at the surface of the tongue and in the glandular tissues. Specific features of chronic alcoholic intoxication include acinar and ductal hyperplasia, reduction of the adipose tissue mass in salivary gland stroma, predominance of T-lymphocytes in hard palate minor salivary glands and B-lymphocytes in the stroma of labial minor salivary gland, the absence of plasma cells in the stroma of hard palate minor salivary glands and labial mucosa. Leukoplakia, dysplasia, and hyperplasia of the basal epithelial layer of oral cavity mucosa are considered to be the signs of long-term (over 12 months) alcohol consumption.
authors.forename: Iu I
authors.initials: IuI
authors.lastname: Pigolkin
authors.forename: O V
authors.initials: OV
authors.lastname: Dolzhanskiĭ
authors.forename: T S
authors.initials: TS
authors.lastname: Mamsurova
authors.forename: A A
authors.initials: AA
authors.lastname: Chertovskikh
mesh_terms: D000328:Adult; D000428:Alcohol Drinking; D000437:Alcoholism / Q000150:complications*; D001706:Biopsy; D003945:Diagnosis, Oral / Q000379:methods; D005260:Female; D049429:Forensic Pathology / Q000379:methods; D006801:Humans; D007150:Immunohistochemistry / Q000379:methods; D008297:Male; D008875:Middle Aged; D009059:Mouth Diseases / Q000209:etiology / Q000473:pathology*; D058958:Organs at Risk; D021362:Palate, Hard / Q000473:pathology*; D012307:Risk Factors; D012469:Salivary Glands / Q000473:pathology*; D012907:Smoking; D014059:Tongue / Q000473:pathology*