title: Kyphoplasty in osteoporotic vertebral compression fractures--guidelines and technical considerations.
abstract: Osteoporotic vertebral compression fractures are a menace to the elderly generation causing diminished quality of life due to pain and deformity. At first, conservative treatment still is the method of choice. In case of resulting deformity, sintering and persistent pain vertebral cement augmentation techniques today are widely used. Open correction of resulting deformity by different types of osteotomies addresses sagittal balance, but has comparably high morbidity. Besides conventional vertebral cement augmentation techniques balloon kyphoplasty has become a popular tool to address painful thoracic and lumbar compression fractures. It showed improved pain reduction and lower complication rates compared to standard vertebroplasty. Interestingly the results of two placebo-controlled vertebroplasty studies question the value of cement augmentation, if compared to a sham operation. Even though there exists now favourable data for kyphoplasty from one randomised controlled trial, the absence of a sham group leaves the placebo effect unaddressed. Technically kyphoplasty can be performed with a transpedicular or extrapedicular access. Polymethyl methacrylate (PMMA)-cement should be favoured, since calcium phosphate cement showed inferior biomechanical properties and less effect on pain reduction especially in less stable burst fractures. Common complications of kyphoplasty are cement leakage and adjacent segment fractures. Rare complications are toxic PMMA-monomer reactions, cement embolisation, and infection.
authors.affiliation: Uppsala University Hospital, Institute for Surgical Sciences, Department of Orthopaedics, Uppsala, Sweden. yohan.robinson@surgsci.uu.se
authors.forename: Yohan
authors.initials: Y
authors.lastname: Robinson
authors.forename: Christoph E
authors.initials: CE
authors.lastname: Heyde
authors.forename: Peter
authors.initials: P
authors.lastname: Försth
authors.forename: Claes
authors.initials: C
authors.lastname: Olerud
mesh_terms: D001843:Bone Cements; D005260:Female; D050815:Fractures, Compression / Q000601:surgery*; D006801:Humans; D058498:Kyphoplasty / Q000379:methods*; D008159:Lumbar Vertebrae / Q000601:surgery; D008297:Male; D058866:Osteoporotic Fractures / Q000601:surgery*; D017410:Practice Guidelines as Topic; D016103:Spinal Fractures / Q000601:surgery*; D013904:Thoracic Vertebrae / Q000601:surgery
chemical_list: D001843:Bone Cements