title: Ovarian cancer during pregnancy.
abstract: OBJECTIVE
  To evaluate the clinical features, pregnancy outcome, and treatment of patients with ovarian cancer diagnosed during pregnancy.
  
  
  METHODS
  The present study was a retrospective review of 11 cases of ovarian cancer detected during pregnancy. The women were treated and followed up at Selçuk University, Meram Faculty of Medicine, Konya, Turkey, during 2006-2010.
  
  
  RESULTS
  Approximately half the patients were asymptomatic (5 [45.5%]) and diagnosed during cesarean delivery (6 [54.5%]). The histopathologic tumor categories comprised malignant epithelial ovarian tumor (4 [36.4%]), borderline tumor (4 [36.4%]), malignant germ cell tumor (2 [18.2%]), and sex cord stromal tumor (1 [9.1%]). Nine (81.8%) tumors were classified as stage I. Conservative surgery was performed in 10 (90.9%) patients. A patient with stage IIIC serous papillary adenocarcinoma underwent hysterectomy with bilateral salpingo-oophorectomy. A patient with dysgerminoma in stage IV died on follow-up. Three infants were born premature; they were followed up in the neonatal intensive care unit with satisfactory outcomes.
  
  
  CONCLUSIONS
  Early diagnosis and appropriate treatment are crucial for patients with ovarian cancer diagnosed during pregnancy. Tumor staging is possible during pregnancy, but the appropriateness of surgery needs to be considered carefully. Ideally, the treatment strategy should be discussed and structured on an individual basis.
authors.affiliation: Department of Obstetrics and Gynecology, Meram Medical School, Selçuk University, Konya, Turkey.
authors.forename: Kazım
authors.initials: K
authors.lastname: Gezginç
authors.forename: Rengin
authors.initials: R
authors.lastname: Karataylı
authors.forename: Fatma
authors.initials: F
authors.lastname: Yazıcı
authors.forename: Ali
authors.initials: A
authors.lastname: Acar
authors.forename: Cetin
authors.initials: C
authors.lastname: Celik
authors.forename: Metin
authors.initials: M
authors.lastname: Capar
mesh_terms: D000328:Adult; D000970:Antineoplastic Agents / Q000008:administration & dosage; D000077216:Carcinoma, Ovarian Epithelial; D002585:Cesarean Section; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D007044:Hysterectomy; D009367:Neoplasm Staging; D009373:Neoplasms, Germ Cell and Embryonal / Q000175:diagnosis / Q000453:epidemiology / Q000473:pathology / Q000628:therapy; D009375:Neoplasms, Glandular and Epithelial / Q000175:diagnosis / Q000453:epidemiology / Q000473:pathology / Q000628:therapy; D010051:Ovarian Neoplasms / Q000175:diagnosis / Q000453:epidemiology* / Q000473:pathology / Q000628:therapy; D010052:Ovariectomy; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000175:diagnosis / Q000453:epidemiology* / Q000473:pathology / Q000628:therapy; D011256:Pregnancy Outcome; D011296:Prenatal Diagnosis; D012189:Retrospective Studies; D018312:Sex Cord-Gonadal Stromal Tumors / Q000175:diagnosis / Q000453:epidemiology / Q000473:pathology / Q000628:therapy; D014421:Turkey / Q000453:epidemiology; D055815:Young Adult
chemical_list: D000970:Antineoplastic Agents