title: [Influence of hemicellulose based anticoagulant on male rat reproductive function].
abstract: Results of estimation of the effect of a new hemicellulose-based anticoagulant drug on the reproductive function of white male rats are presented. No negative impact on the fertility and breed was observed for the drug administered in doses of 5 and 25 mg/kg. However, in a dose of 50 mg/kg, the new drug negatively affected spermatogenesis and decrease the reproductive function of male rats.
authors.forename: T E
authors.initials: TE
authors.lastname: Vladimirskaia
authors.forename: I A
authors.initials: IA
authors.lastname: Shved
authors.forename: N N
authors.initials: NN
authors.lastname: Veialkina
authors.forename: A V
authors.initials: AV
authors.lastname: Adamovich
authors.forename: S G
authors.initials: SG
authors.lastname: Krivorot
authors.forename: F N
authors.initials: FN
authors.lastname: Kaputskiĭ
mesh_terms: D000818:Animals; D000925:Anticoagulants / Q000008:administration & dosage* / Q000009:adverse effects; D004195:Disease Models, Animal; D004305:Dose-Response Relationship, Drug; D005260:Female; D005298:Fertility / Q000187:drug effects; D005328:Fetal Viability / Q000187:drug effects; D008297:Male; D015394:Molecular Structure; D011134:Polysaccharides / Q000008:administration & dosage / Q000009:adverse effects; D011247:Pregnancy; D051381:Rats; D012098:Reproduction / Q000187:drug effects*; D013091:Spermatogenesis / Q000187:drug effects*; D013094:Spermatozoa / Q000187:drug effects / Q000473:pathology
chemical_list: D000925:Anticoagulants; D011134:Polysaccharides; C007916:hemicellulose