title: Late stent thrombosis after drug-eluting stent implantation: a rare case of accelerated neo-atherosclerosis and early manifestation of neointimal rupture.
abstract: An 80-year old woman suffered from sudden onset of chest pain and dyspnea, and visited the emergency room. She received stent implantation with a biolimus A9-eluting stent (Nobori® 3.0×24 mm) at a the mid-portion of the left anterior descending artery 5 months prior to admission. The emergency 5-month follow-up angiogram was performed under the impression of late stent thrombosis. The follow-up angiogram showed subtotal occlusion at the mid-portion of the left anterior descending artery, which was the same segment of previous stent implantation 5 months ago. Immediately after thrombus aspiration with the thrombus aspiration catheter, the optical coherence tomography showed layered appearance of neointimal hyperplasia and neointimal rupture within the previously stented segment. Thus, neointimal rupture within accelerated growth of neointimal tissue was observed within a relatively shorter period (i.e., about 5 months) after stent implantation.
authors.affiliation: Division of Cardiology, Severance Cardiovascular Hospital, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: Young-June
authors.initials: YJ
authors.lastname: Yang
authors.forename: Mihyun
authors.initials: M
authors.lastname: Kim
authors.forename: Choongki
authors.initials: C
authors.lastname: Kim
authors.forename: Junbeom
authors.initials: J
authors.lastname: Park
authors.forename: Jaewon
authors.initials: J
authors.lastname: Oh
authors.forename: Hoyoun
authors.initials: H
authors.lastname: Won
authors.forename: Byeong-Keuk
authors.initials: BK
authors.lastname: Kim
authors.forename: Myeong-Ki
authors.initials: MK
authors.lastname: Hong