title: Natural history and outcome of mucinous carcinoma of the ovary.
abstract: OBJECTIVE
  We performed a population-based analysis to compare the clinical characteristics of women with mucinous tumors with women with other epithelial tumors.
  
  
  METHODS
  The Surveillance, Epidemiology, and End Results database was queried to identify all women with epithelial ovarian cancer diagnosed from 1988 to 2007. The natural history, clinical characteristics, and survival of women with serous tumors were compared with women with mucinous carcinomas.
  
  
  RESULTS
  A total of 40,571 women including 4811 with mucinous carcinomas (11.9%) were identified. Among women with stage I neoplasms, the presence of mucinous histology had no effect on either cancer-specific survival (hazard ratio, 0.87; 95% confidence interval, 0.74-1.04). Survival was inferior in patients with advanced-stage mucinous compared with serous tumors. The hazard ratio for cancer-specific survival for women with stage III mucinous tumors was 1.55 (95% confidence interval, 1.43-1.96).
  
  
  CONCLUSIONS
  Although survival for early-stage mucinous and serous tumors is similar, survival for advanced-stage mucinous neoplasms is inferior to that of serous carcinomas.
authors.affiliation: Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, College of Physicians and Surgeons, Columbia University, New York, NY, USA.
authors.forename: Maria B
authors.initials: MB
authors.lastname: Schiavone
authors.forename: Thomas J
authors.initials: TJ
authors.lastname: Herzog
authors.forename: Sharyn N
authors.initials: SN
authors.lastname: Lewin
authors.forename: Israel
authors.initials: I
authors.lastname: Deutsch
authors.forename: Xuming
authors.initials: X
authors.lastname: Sun
authors.forename: William M
authors.initials: WM
authors.lastname: Burke
authors.forename: Jason D
authors.initials: JD
authors.lastname: Wright
mesh_terms: D002288:Adenocarcinoma, Mucinous / Q000401:mortality / Q000473:pathology*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D018450:Disease Progression; D005260:Female; D006801:Humans; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000401:mortality / Q000473:pathology*; D010053:Ovary / Q000473:pathology*; D011379:Prognosis; D018426:SEER Program; D015996:Survival Rate; D014481:United States