title: Base-free two-step synthesis of 1,3-diketones and β-ketoesters from α-diazocarbonyl compounds, trialkylboranes, and aromatic aldehydes.
abstract: We describe a convergent, base-free two-step synthesis of 1,3-diketones and β-ketoesters from α-diazocarbonyl compounds, trialkylboranes, and aromatic aldehydes in a three-component process. The synthetic potential of this protocol was underscored by the synthesis of several symmetrical 1,3,5-triaryl-4-alkyl and 1,3,4,5-tetraryl substituted pyrazoles in a three-step sequence.
authors.affiliation: Instituto de Química, Universidad Nacional Autónoma de México, Circuito Exterior, Ciudad Universitaria, Coyoacán México, DF 04510, México.
authors.forename: Miguel A
authors.initials: MA
authors.lastname: Sanchez-Carmona
authors.forename: David A
authors.initials: DA
authors.lastname: Contreras-Cruz
authors.forename: Luis D
authors.initials: LD
authors.lastname: Miranda
mesh_terms: D000447:Aldehydes / Q000737:chemistry*; D001391:Azo Compounds / Q000737:chemistry*; D001880:Boranes / Q000737:chemistry*; D060326:Chemistry Techniques, Synthetic; D004952:Esters / Q000138:chemical synthesis* / Q000737:chemistry; D007659:Ketones / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D000447:Aldehydes; D001391:Azo Compounds; D001880:Boranes; D004952:Esters; D007659:Ketones