title: [Alkaline phosphatase in mixed saliva in abdominal inflammatory diseases and gestoses].
abstract: By applying enzyme electrophoresis in the agar gel prepared on veronal-medinal buffer (pH 8.6) (the substrate was naphthol AS phosphate; the dye was fast blue B or PP), the authors first revealed mixed salivary alkaline phosphatase (AP) that differed in physicochemical properties from the known serum AP isoforms, in 63% of patients with cholecystitis or pancreatitis, in 90% of those with appendicitis, and in 55.3% of pregnant women with second- and third-degree gestoses. After treatment, the detection rate for salivary AP significantly decreased to 16.6, 40.0, and 6.4%, respectively. This noninvasive test may be useful for the additional diagnosis and monitoring of treatment for abdominal inflammatory diseases and gestational toxicosis.
authors.forename: A E
authors.initials: AE
authors.lastname: Sukhareva
authors.forename: N A
authors.initials: NA
authors.lastname: Bulakh
authors.forename: T N
authors.initials: TN
authors.lastname: Ermolaeva
authors.forename: A A
authors.initials: AA
authors.lastname: Nikolaeva
mesh_terms: D000328:Adult; D000469:Alkaline Phosphatase / Q000032:analysis*; D001064:Appendicitis / Q000175:diagnosis* / Q000188:drug therapy; D002764:Cholecystitis / Q000175:diagnosis* / Q000188:drug therapy; D004586:Electrophoresis; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008991:Monitoring, Physiologic; D010195:Pancreatitis / Q000175:diagnosis* / Q000188:drug therapy; D011225:Pre-Eclampsia / Q000175:diagnosis* / Q000188:drug therapy; D011247:Pregnancy; D012463:Saliva / Q000201:enzymology*
chemical_list: D000469:Alkaline Phosphatase