title: Environmental microbiota represents a natural reservoir for dissemination of clinically relevant metallo-beta-lactamases.
abstract: A total of 10 metallo-β-lactamase-producing isolates of six different species, including Brevundimonas diminuta (n = 3), Rhizobium radiobacter (n = 2), Pseudomonas monteilii (n = 1), Pseudomonas aeruginosa (n = 2), Ochrobactrum anthropi (n = 1), and Enterobacter ludwigii (n = 1), were detected in the sewage water of a hospital. The presence of bla(VIM-13) associated with a Tn1721-class 1 integron structure was detected in all but one of the isolates (E. ludwigii, which produced VIM-2), and in two of them (R. radiobacter), this structure was located on a plasmid, suggesting that environmental bacteria represent a reservoir for the dissemination of clinically relevant metallo-β-lactamase genes.
authors.affiliation: Área de Microbiología, Universidad de las Islas Baleares, Palma de Mallorca, Spain.
authors.forename: Claudia
authors.initials: C
authors.lastname: Scotta
authors.forename: Carlos
authors.initials: C
authors.lastname: Juan
authors.forename: Gabriel
authors.initials: G
authors.lastname: Cabot
authors.forename: Antonio
authors.initials: A
authors.lastname: Oliver
authors.forename: Jorge
authors.initials: J
authors.lastname: Lalucat
authors.forename: Antonio
authors.initials: A
authors.lastname: Bennasar
authors.forename: Sebastián
authors.initials: S
authors.lastname: Albertí
mesh_terms: D016960:Agrobacterium tumefaciens / Q000201:enzymology / Q000235:genetics; D004754:Enterobacter / Q000201:enzymology / Q000235:genetics; D006761:Hospitals; D032023:Integrons / Q000235:genetics; D020621:Ochrobactrum anthropi / Q000201:enzymology / Q000235:genetics; D010957:Plasmids / Q000235:genetics; D011549:Pseudomonas / Q000201:enzymology / Q000235:genetics; D011550:Pseudomonas aeruginosa / Q000201:enzymology / Q000235:genetics; D012722:Sewage / Q000382:microbiology; D014871:Water Microbiology; D001618:beta-Lactamases / Q000235:genetics*
chemical_list: D012722:Sewage; D001618:beta-Lactamases