title: Assessing atropisomer axial chirality in drug discovery and development.
authors.affiliation: Department of Chemistry, Boehringer Ingelheim (Canada) Ltd., 2100 Cunard Street, Laval, Quebec, H7S 2G5, Canada. steven.laplante@boehringer-ingelheim.com
authors.forename: Steven R
authors.initials: SR
authors.lastname: Laplante
authors.forename: Lee
authors.initials: L
authors.lastname: D Fader
authors.forename: Keith R
authors.initials: KR
authors.lastname: Fandrick
authors.forename: Daniel R
authors.initials: DR
authors.lastname: Fandrick
authors.forename: Oliver
authors.initials: O
authors.lastname: Hucke
authors.forename: Ray
authors.initials: R
authors.lastname: Kemper
authors.forename: Stephen P F
authors.initials: SP
authors.lastname: Miller
authors.forename: Paul J
authors.initials: PJ
authors.lastname: Edwards
mesh_terms: D000577:Amides / Q000737:chemistry; D055808:Drug Discovery; D006576:Heterocyclic Compounds, 4 or More Rings / Q000737:chemistry; D007880:Legislation, Drug; D047028:Macrocyclic Compounds / Q000737:chemistry; D008958:Models, Molecular; D004364:Pharmaceutical Preparations / Q000737:chemistry*; D010599:Pharmacokinetics; D013237:Stereoisomerism; D013329:Structure-Activity Relationship; D013816:Thermodynamics; D014481:United States; D014486:United States Food and Drug Administration
chemical_list: D000577:Amides; D006576:Heterocyclic Compounds, 4 or More Rings; D047028:Macrocyclic Compounds; D004364:Pharmaceutical Preparations