title: Superquencher formation via nucleic acid induced noncovalent perylene probe self-assembly.
abstract: A fluorophore labeled oligonucleotide could induce aggregation of a positively charged perylene probe. The perylene aggregate could very efficiently quench the fluorescence of the labeled fluorophore. Based on this observation, a new method for the highly sensitive and selective detection of a protein has been developed.
authors.affiliation: State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, PR China.
authors.forename: Bin
authors.initials: B
authors.lastname: Wang
authors.forename: Huping
authors.initials: H
authors.lastname: Jiao
authors.forename: Wenying
authors.initials: W
authors.lastname: Li
authors.forename: Dongli
authors.initials: D
authors.lastname: Liao
authors.forename: Fangyuan
authors.initials: F
authors.lastname: Wang
authors.forename: Cong
authors.initials: C
authors.lastname: Yu
mesh_terms: D008958:Models, Molecular; D008968:Molecular Conformation; D009696:Nucleic Acids / Q000737:chemistry*; D015345:Oligonucleotide Probes / Q000737:chemistry*; D010569:Perylene / Q000737:chemistry*; D013050:Spectrometry, Fluorescence
chemical_list: D009696:Nucleic Acids; D015345:Oligonucleotide Probes; D010569:Perylene