title: Clinical value of integrated [18F]fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography in the preoperative assessment of papillary thyroid carcinoma: comparison with sonography.
abstract: OBJECTIVE
  The purpose of this study was to evaluate the clinical value of preoperative [(18)F]fluoro-2-deoxy-D-glucose (FDG) positron emission tomography/computed tomography (PET/CT) by comparing it to neck sonography in papillary thyroid carcinoma.
  
  
  METHODS
  The diagnostic accuracies of PET/CT and sonography for detecting cervical node metastasis were compared. The association between FDG uptake in the primary tumor and the prognostic factors of differentiated thyroid cancer, such as tumor size, multiplicity, extrathyroid extension, and lymph node metastasis, was also assessed.
  
  
  RESULTS
  Positron emission tomography/computed tomography showed lower sensitivity and higher specificity than sonography for detection of cervical node metastasis; however, no statistically significant difference was noted (P > .99). Only the tumor size was associated with FDG uptake in the primary tumor.
  
  
  CONCLUSIONS
  [(18)F]Fluoro-2-deoxy-d-glucose PET/CT could not provide additional information compared to neck sonography.
authors.affiliation: Department of Radiology, Seoul St Mary's Hospital, Seoul, Korea.
authors.forename: Woo Hee
authors.initials: WH
authors.lastname: Choi
authors.forename: Yong-An
authors.initials: YA
authors.lastname: Chung
authors.forename: Eun Ji
authors.initials: EJ
authors.lastname: Han
authors.forename: Hyung Sun
authors.initials: HS
authors.lastname: Sohn
authors.forename: Sang Hoon
authors.initials: SH
authors.lastname: Lee
mesh_terms: D000328:Adult; D000368:Aged; D002277:Carcinoma; D002291:Carcinoma, Papillary; D016009:Chi-Square Distribution; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008207:Lymphatic Metastasis / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D049268:Positron-Emission Tomography / Q000379:methods*; D057234:Preoperative Period; D011379:Prognosis; D019275:Radiopharmaceuticals; D012680:Sensitivity and Specificity; D000077273:Thyroid Cancer, Papillary; D013964:Thyroid Neoplasms / Q000000981:diagnostic imaging*; D014057:Tomography, X-Ray Computed / Q000379:methods*; D014463:Ultrasonography
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18