title: Preventive misconception as a motivation for participation and adherence in microbicide trials: evidence from female participants and male partners in Malawi and Zimbabwe.
abstract: This paper presents empirical data on motivation to join an HIV prevention trial of vaginal microbicide gels in Malawi and Zimbabwe, and participant assumption of a preventive misconception. Interviews were conducted with women participating in the trial and their male partners. Most of the female participants were able to adequately describe basic aspects of the trial design. HIV counseling and testing were primary reasons motivating women's participation, and male partners' support of the trial. 29% of women and 20% of men also provided indications of a preventive misconception, attributing gel use and trial participation to avoiding HIV infection.
authors.affiliation: International Partnership for Microbicides, Main Street 121, Paarl 7646, South Africa. cwoodsong@ipmglobal.org
authors.forename: Cynthia
authors.initials: C
authors.lastname: Woodsong
authors.forename: Patty
authors.initials: P
authors.lastname: Alleman
authors.forename: Petina
authors.initials: P
authors.lastname: Musara
authors.forename: Adlight
authors.initials: A
authors.lastname: Chandipwisa
authors.forename: Mike
authors.initials: M
authors.lastname: Chirenje
authors.forename: Francis
authors.initials: F
authors.lastname: Martinson
authors.forename: Irving
authors.initials: I
authors.lastname: Hoffman
mesh_terms: D000180:Acrylic Resins / Q000008:administration & dosage; D019380:Anti-HIV Agents / Q000008:administration & dosage; D017322:Clinical Trials, Phase II as Topic / Q000379:methods / Q000523:psychology*; D004311:Double-Blind Method; D005260:Female; D015658:HIV Infections / Q000517:prevention & control* / Q000523:psychology / Q000635:transmission; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D007407:Interviews as Topic; D008295:Malawi; D008297:Male; D055118:Medication Adherence / Q000523:psychology*; D009042:Motivation; D009282:Naphthalenesulfonates / Q000008:administration & dosage; D010358:Patient Participation / Q000523:psychology*; D011108:Polymers / Q000008:administration & dosage; D016032:Randomized Controlled Trials as Topic / Q000379:methods / Q000523:psychology*; D012747:Sexual Partners / Q000523:psychology; D015030:Zimbabwe
chemical_list: D000180:Acrylic Resins; D019380:Anti-HIV Agents; C420918:BufferGel; D009282:Naphthalenesulfonates; C120231:PRO 2000; D011108:Polymers