title: Drug surveillance programme in psychiatry - adverse durg reactions.
abstract: In a clinically monitored surveillance of adverse drug reactions in a sample of 186 indoor patients in a general hospital over an average hospital stay of about two weeks, the following points were noteworthy. 32.8% of the patients reported side-effects and of these 79.3% were of mild to moderate intensity.Side-effects could be easily managed by specific antidotes and reassurance and permitted continuation of the same medication.There was no association between side-effects and socio-demography or clinical characteristics of the patient. Side-effects fitted in with the pharmacological profiles of the drugs used. In only 7.3% of cases was major treatment change made after the occurrence of the side effect. Improvement was independent of side-effects and no unusual or toxic reactions were seen.
authors.affiliation: Prof. of Psychiatry, Department of Psychiatry & Department of Pharmacology & Clinical Pharmacology Unit, Seth G. S. Medical College & K.E.M. Hospital, Parel, Bombay 400 012.
authors.forename: L P
authors.initials: LP
authors.lastname: Shah
authors.forename: K S
authors.initials: KS
authors.lastname: Ayyar
authors.forename: B R
authors.initials: BR
authors.lastname: Agarawal
authors.forename: P V
authors.initials: PV
authors.lastname: Pradhan
authors.forename: V N
authors.initials: VN
authors.lastname: Bagadia
authors.forename: K C
authors.initials: KC
authors.lastname: Gupta
authors.forename: T
authors.initials: T
authors.lastname: Paul
authors.forename: H
authors.initials: H
authors.lastname: Santhanam
authors.forename: U K
authors.initials: UK
authors.lastname: Sheth