title: Nucleic acid amphiphiles: synthesis and self-assembled nanostructures.
abstract: This review provides an overview of a relatively new class of bio-conjugates, DNA amphiphiles, which consist of oligonucleotides covalently bonded to synthetic hydrophobic units. The reader will find the basic principles for the structural design and preparation methods of the materials. Moreover, the self-assembly into superstructures of higher order will be highlighted. Finally, some potential applications will be described.
authors.affiliation: Department of Polymer Chemistry, Zernike Institute for Advanced Materials, University of Groningen, Groningen, The Netherlands.
authors.forename: Minseok
authors.initials: M
authors.lastname: Kwak
authors.forename: Andreas
authors.initials: A
authors.lastname: Herrmann
mesh_terms: D000818:Animals; D060326:Chemistry Techniques, Synthetic / Q000379:methods*; D004247:DNA / Q000138:chemical synthesis* / Q000737:chemistry*; D057927:Hydrophobic and Hydrophilic Interactions; D053761:Nanocomposites / Q000737:chemistry; D049329:Nanostructures / Q000737:chemistry*; D009838:Oligodeoxyribonucleotides / Q000138:chemical synthesis / Q000737:chemistry
chemical_list: D009838:Oligodeoxyribonucleotides; D004247:DNA