title: [Immunosupressive effect of hypokinetic stress and sensitization of thymus to glucocorticoids].
abstract: 24-hour hypokinetic stress expressed in decrease of sensitivity of cellular and humoral immu nity to subsequent immunization with sheep erythrocytes was studied. The development of this phenomenon is associated with sensitization of lymphoid tissue to hypoplasia effect of glycocorticoid hormones. In introduction of glycocorticoid stress, the animals revealed a more pronounced depression of proliferative activity of thymocytes compared with non stressed animals.
authors.forename: V É
authors.initials: VÉ
authors.lastname: Tseĭlikman
authors.forename: T A
authors.initials: TA
authors.lastname: Filimonova
authors.forename: S V
authors.initials: SV
authors.lastname: Sibiriak
authors.forename: A I
authors.initials: AI
authors.lastname: Sinitskiĭ
authors.forename: D A
authors.initials: DA
authors.lastname: Kozochkin
authors.forename: L A
authors.initials: LA
authors.lastname: Strel'nikova
mesh_terms: D000818:Animals; D017209:Apoptosis / Q000187:drug effects; D002452:Cell Count; D049109:Cell Proliferation / Q000187:drug effects; D002469:Cell Separation; D002478:Cells, Cultured; D004912:Erythrocytes / Q000276:immunology; D005938:Glucocorticoids / Q000494:pharmacology*; D006968:Hypersensitivity, Delayed / Q000276:immunology / Q000503:physiopathology; D018476:Hypokinesia / Q000276:immunology* / Q000503:physiopathology; D007108:Immune Tolerance; D007111:Immunity, Cellular / Q000187:drug effects*; D056724:Immunity, Humoral / Q000187:drug effects; D007114:Immunization / Q000379:methods; D007274:Injections, Intraperitoneal; D008938:Mitosis / Q000187:drug effects; D051381:Rats; D017208:Rats, Wistar; D012756:Sheep; D013601:T-Lymphocytes / Q000166:cytology / Q000276:immunology*; D013950:Thymus Gland / Q000166:cytology / Q000276:immunology*
chemical_list: D005938:Glucocorticoids