title: Chemical constituents from the roots of Xanthium sibiricum.
abstract: Xanthium sibiricum patrin ex Widder (Compositae) is an annual herb which grows all around China. Chemical investigations of its roots resulted in the identification of 15 compounds: stigmast-4-en-6β-ol-3-one (1), β-sitostenone (2), β-sitosterol (3), nonadecanoic acid (4), 5α,8α-epidioxy-22E-ergosta-6,22-dien-3β-ol (5), scopoletin (6), Jatrocin B (7), (±)syringaresinol (8), 9,9'-O-di-(E)-feruloyl-(-)-secoisolariciresinol (9), cleomiscosin A (10), cleomiscosin C (11), N-trans-feruloyl tyramine (12), daucosterol (13), 5-methyluracil (14) and uracil (15). Structures were elucidated by spectroscopic (NMR and MS) methods and confirmed by comparing with reference samples and literature data. Compounds 1-2, 4-12, 14, and 15 were isolated from this genus for the first time, while this is the first report of coumarinolignoids in the Compositae family, and coumarinoligoids could be considered as valuable chemotaxonomic markers for the plant.
authors.affiliation: Key Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education, College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou 571158, P R China.
authors.forename: Suqin
authors.initials: S
authors.lastname: Kan
authors.forename: Guangying
authors.initials: G
authors.lastname: Chen
authors.forename: Changri
authors.initials: C
authors.lastname: Han
authors.forename: Zhong
authors.initials: Z
authors.lastname: Chen
authors.forename: Xinming
authors.initials: X
authors.lastname: Song
authors.forename: Ming
authors.initials: M
authors.lastname: Ren
authors.forename: Hong
authors.initials: H
authors.lastname: Jiang
mesh_terms: D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D018517:Plant Roots / Q000737:chemistry*; D031210:Xanthium / Q000737:chemistry*