title: [Alcohol-induced changes of biogenic amine-containing structures of the large intestine].
abstract: Using the methods of luminescent microscopy and cytospectrofluorometry, biogenic amine-containing structures were studied in colon of rats subjected to alcohol intoxication of 2, 4 and 6 months' duration. It was demonstrated that 2- and 4-month-long alcohol intoxication of animals resulted in biogenic amine content increase in the mucosal surface epithelium, submucosal mast cells and adrenergic nerve fibers within the connective tissue bands in the muscular tunic. At the same time, 6 month-long intoxication was accompanied by a stabilization of bioamine content at the elevated level.
authors.forename: L M
authors.initials: LM
authors.lastname: Iakovleva
authors.forename: L A
authors.initials: LA
authors.lastname: Liubovtseva
authors.forename: M D
authors.initials: MD
authors.lastname: Timofeeva
authors.forename: O S
authors.initials: OS
authors.lastname: Krotkova
mesh_terms: D000320:Adrenergic Fibers / Q000187:drug effects / Q000378:metabolism; D000435:Alcoholic Intoxication / Q000378:metabolism*; D000818:Animals; D001679:Biogenic Amines / Q000378:metabolism*; D003106:Colon / Q000187:drug effects / Q000473:pathology; D000431:Ethanol / Q000008:administration & dosage*; D008407:Mast Cells / Q000187:drug effects / Q000378:metabolism; D008856:Microscopy, Fluorescence; D009092:Mucous Membrane / Q000187:drug effects / Q000378:metabolism; D051381:Rats; D013997:Time Factors
chemical_list: D001679:Biogenic Amines; D000431:Ethanol