title: [One case of correlation between the human herpesvirus 7 DNA load and the hemo hagocytic syndrome].
abstract: OBJECTIVE
  To research the relationship between human herpesvirus 7 (HHV-7) viral Load and the etiopathogenisis of hemophagocytic syndrome, in order to provide evidence for the clinical diagnosis of hemophagocytic syndrome and anti-virus therapy.
  
  
  METHODS
  Peripheral blood of patient with hemophagocytic syndrome during different treatment periods, extracted DNA, Syntheticed the primers of HHV-7, gene sequence of PCR amplified fragments detected, determined HHV-7 viral Load by Real-time fluorescent quantitative PCR and the ferritin concentration in peripheral blood detected by chemiluminescence.
  
  
  RESULTS
  The sequence result indicated that PCR amplified fragment was a part of HHV-7 gene, the ferritin concentration viried with the load of HHV-7.
  
  
  CONCLUSIONS
  The occurrence of hemophagocytic syndrome is connetted with the load of HHV-7.
authors.affiliation: Beijing Dao Pei Hospital, Beijing 100039, China.
authors.forename: Peng
authors.initials: P
authors.lastname: Cai
authors.forename: Chun-rong
authors.initials: CR
authors.lastname: Tong
authors.forename: Jun-fang
authors.initials: JF
authors.lastname: Yang
authors.forename: Ying
authors.initials: Y
authors.lastname: Liu
authors.forename: Guo-lin
authors.initials: GL
authors.lastname: Xu
authors.forename: Gian-feng
authors.initials: GF
authors.lastname: Zhang
authors.forename: Cheng-liang
authors.initials: CL
authors.lastname: Zhen
authors.forename: Gun-fang
authors.initials: GF
authors.lastname: Li
authors.forename: Zhi-ping
authors.initials: ZP
authors.lastname: Teng
mesh_terms: D005293:Ferritins / Q000378:metabolism; D016199:Herpesvirus 7, Human / Q000235:genetics / Q000302:isolation & purification* / Q000502:physiology*; D006801:Humans; D051359:Lymphohistiocytosis, Hemophagocytic / Q000378:metabolism / Q000821:virology*; D019562:Viral Load
chemical_list: D005293:Ferritins