title: Brain oxygenation monitoring during neonatal resuscitation of very low birth weight infants.
abstract: OBJECTIVE
  To explore if regional cerebral tissue oxygen saturation monitoring by near-infrared spectroscopy (NIRS) is feasible during neonatal resuscitation of very low birth weight (VLBW) infants after birth.
  
  
  METHODS
  Cerebral tissue oxygen saturation was measured by NIRS in 51 VLBW infants (mean gestational age: 27.8 weeks) during the first 10 min after delivery.
  
  
  RESULTS
  A regional cerebral tissue oxygen saturation signal was available after a median (interquartile range) age of 52 (44 to 68) s. In three infants the signal was obtained after 10 min of age. After delivery cerebral tissue oxygen saturation rose continuously from 37 (31 to 49) % at 1 minute of age and reached a steady state in the range of 61 to 84% ∼7 min after birth. Percentiles of cerebral tissue oxygen saturation of this cohort of preterm infants are given.
  
  
  CONCLUSIONS
  Cerebral tissue oxygen saturation monitoring is feasible during neonatal resuscitation of VLBW infants within the first minutes of life.
authors.affiliation: Division of Neonatology and Pediatric Intensive Care, Department of Pediatrics, University Medical Center Ulm, Ulm, Germany. hans.fuchs@uniklinik-ulm.de
authors.forename: H
authors.initials: H
authors.lastname: Fuchs
authors.forename: W
authors.initials: W
authors.lastname: Lindner
authors.forename: A
authors.initials: A
authors.lastname: Buschko
authors.forename: M
authors.initials: M
authors.lastname: Almazam
authors.forename: H D
authors.initials: HD
authors.lastname: Hummler
authors.forename: M B
authors.initials: MB
authors.lastname: Schmid
mesh_terms: D001921:Brain / Q000098:blood supply; D002545:Brain Ischemia / Q000517:prevention & control; D016887:Cardiopulmonary Resuscitation / Q000379:methods*; D002423:Cause of Death; D002560:Cerebrovascular Circulation / Q000502:physiology*; D015331:Cohort Studies; D005240:Feasibility Studies; D005260:Female; D005865:Gestational Age; D017052:Hospital Mortality / Q000639:trends; D006801:Humans; D007231:Infant, Newborn; D019102:Infant, Very Low Birth Weight; D007363:Intensive Care Units, Neonatal; D008297:Male; D008991:Monitoring, Physiologic / Q000379:methods; D010092:Oximetry / Q000379:methods; D010101:Oxygen Consumption / Q000502:physiology*; D011247:Pregnancy; D011379:Prognosis; D012189:Retrospective Studies; D018570:Risk Assessment; D019265:Spectroscopy, Near-Infrared / Q000379:methods*; D015996:Survival Rate; D013997:Time Factors