title: Oral health status, salivary factors and microbial analysis in patients with active gastro-oesophageal reflux disease.
abstract: OBJECTIVE
  To present a complex oral health status including salivary factors, microbial analysis and periodontal and hygiene indices in patients with active gastro-oesophageal reflux disease (GORD). Return of stomach contents is quite common in cases of gastro-oesophageal reflux. Pathological acid movement from the stomach into the oesophagus and oral cavity may lead to a development of dental erosion. Long-lasting untreated GORD may damage hard dental and periodontal tissues and alter the oral microbial environment. The quality and amount of the saliva play an important role in hard and soft oral tissues changes.
  
  
  METHODS
  Fifty patients with diagnosed GORD using 24-hour pH manometry underwent dental examination; 24 patients had active GORD and had been waiting for surgical therapy. In this patient group oral health status and salivary analysis were evaluated.
  
  
  RESULTS
  Indicated low salivary flow rates and buffering capacity with a low caries risk but a high risk for dental erosion progression.
authors.affiliation: Department of Conservative Dentistry, St Anna's Faculty Hospital, and Faculty of Medicine, Masaryk University, Brno, Czech Republic. 44343@mail.muni.cz
authors.forename: Kristina
authors.initials: K
authors.lastname: Filipi
authors.forename: Zdenka
authors.initials: Z
authors.lastname: Halackova
authors.forename: Vladimir
authors.initials: V
authors.lastname: Filipi
mesh_terms: D000328:Adult; D002021:Buffers; D015169:Colony Count, Microbial; D004245:DMF Index; D003731:Dental Caries / Q000209:etiology* / Q000382:microbiology; D003773:Dental Plaque / Q000382:microbiology*; D005260:Female; D005764:Gastroesophageal Reflux / Q000150:complications*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007778:Lactobacillus / Q000302:isolation & purification; D008297:Male; D008365:Manometry; D008875:Middle Aged; D009909:Oral Health; D010512:Periodontal Index; D012307:Risk Factors; D012463:Saliva / Q000737:chemistry / Q000378:metabolism* / Q000382:microbiology; D012636:Secretory Rate; D013295:Streptococcus mutans / Q000302:isolation & purification; D014077:Tooth Erosion / Q000209:etiology*
chemical_list: D002021:Buffers