title: Intramolecular Povarov reactions involving 3-aminocoumarins.
abstract: A series of pentacyclic heterocyclic systems (15 examples, 69-89%) have been synthesized using intramolecular Povarov reactions involving 3-aminocoumarins and O-cinnamylsalicylaldehydes. The Povarov adducts are formed with high selectivity for the trans,trans relative stereochemistry in the newly-formed [6,6] fused ring system. One example of a Povarov adduct featuring a new [6,5] fused ring system is reported. In this case, cis,trans relative stereochemistry was preferred.
authors.affiliation: Department of Chemistry, Memorial University, St. John's, NL, Canada A1B 3X7.
authors.forename: Amit A
authors.initials: AA
authors.lastname: Kudale
authors.forename: David O
authors.initials: DO
authors.lastname: Miller
authors.forename: Louise N
authors.initials: LN
authors.lastname: Dawe
authors.forename: Graham J
authors.initials: GJ
authors.lastname: Bodwell