title: [Radiotherapy of lung cancer: Any room left for elective mediastinal irradiation in 2011?].
abstract: Traditionally, the target volumes of curative-intent radiotherapy for non-small cell lung cancer include all uninvolved mediastinal nodes. However, an improvement in tumour control requires an increase of the total dose to the macroscopic target volume. This is only achievable if the irradiation of the organs at risk is reduced, i.e. elective irradiation of the mediastinum is omitted. The available data suggest that elective mediastinal irradiation may be safely omitted, provided that an adequate staging procedure, including FDG PET-CT, has been performed.
authors.affiliation: Département de radiothérapie-oncologie, institut Jules-Bordet, Bruxelles, Belgique. paul.vanhoutte@bordet.be
authors.forename: P
authors.initials: P
authors.lastname: Van Houtte
authors.forename: M
authors.initials: M
authors.lastname: Roelandts
authors.forename: F
authors.initials: F
authors.lastname: Mornex
mesh_terms: D002289:Carcinoma, Non-Small-Cell Lung / Q000532:radiotherapy* / Q000556:secondary*; D005462:Fluorine Radioisotopes; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008175:Lung Neoplasms / Q000532:radiotherapy*; D015182:Lymphatic Irradiation / Q000009:adverse effects / Q000379:methods*; D008207:Lymphatic Metastasis / Q000000981:diagnostic imaging / Q000517:prevention & control / Q000532:radiotherapy*; D008482:Mediastinum / Q000528:radiation effects*; D009367:Neoplasm Staging / Q000379:methods; D058958:Organs at Risk; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals; D014057:Tomography, X-Ray Computed; D019564:Unnecessary Procedures
chemical_list: D005462:Fluorine Radioisotopes; D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18