title: Diagnosis of congenital toxoplasmosis by polymerase chain reaction on neonatal peripheral blood.
abstract: In a cohort of 12 consecutive neonates, polymerase chain reaction (PCR) established the diagnosis of 5 of 6 cases of congenital toxoplasmosis and did so earlier than serologic methods. We validated that PCR using neonatal peripheral blood is a sensitive, rapid, and cost-effective method to affirm the diagnosis of previously undiagnosed congenital toxoplasmosis.
authors.affiliation: Department of Parasitology-Mycology, Faculty of Medicine, University Hospital Centre of Montpellier and University Montpellier I, Montpellier, France. y-sterkers@chu-montpellier.fr
authors.forename: Yvon
authors.initials: Y
authors.lastname: Sterkers
authors.forename: Jennifer
authors.initials: J
authors.lastname: Ribot
authors.forename: Sahar
authors.initials: S
authors.lastname: Albaba
authors.forename: Eric
authors.initials: E
authors.lastname: Issert
authors.forename: Patrick
authors.initials: P
authors.lastname: Bastien
authors.forename: Francine
authors.initials: F
authors.lastname: Pratlong
mesh_terms: D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007231:Infant, Newborn; D018445:Infectious Disease Transmission, Vertical; D016133:Polymerase Chain Reaction / Q000379:methods*; D011247:Pregnancy; D015597:Pregnancy Complications, Parasitic / Q000175:diagnosis; D011446:Prospective Studies; D014122:Toxoplasma / Q000302:isolation & purification / Q000472:pathogenicity; D014125:Toxoplasmosis, Congenital / Q000097:blood* / Q000175:diagnosis* / Q000469:parasitology