title: When the going gets tough, memory T cells check out.
abstract: Memory CD8(+) T cells proliferate faster than naive cells to rapidly control an infectious challenge, but West et al. (2011) in this issue of Immunity report that this superiority is lost in the face of a high dose or chronic viral challenge.
authors.affiliation: Department of Molecular Microbiology and Immunology, Oregon Health and Science University, Portland, OR 97239, USA. hillan@ohsu.edu
authors.forename: Ann
authors.initials: A
authors.lastname: Hill