title: Lung cancer risk in painters: a meta-analysis.
abstract: We conducted a meta-analysis to quantitatively compare the association between occupation as a painter and the incidence or mortality from lung cancer. PubMed and the reference lists of pertinent publications were searched and reviewed. For the meta-analysis, we used data from 47 independent cohort, record linkage, and case-control studies (from a total of 74 reports), including > 11,000 incident cases or deaths from lung cancer among painters. Three authors independently abstracted data and assessed study quality. The summary relative risk (meta-RR, random effects) for lung cancer in painters was 1.35 [95% confidence interval (CI), 1.29-1.41; 47 studies] and 1.35 (95% CI, 1.21-1.51; 27 studies) after controlling for smoking. The relative risk was higher in never-smokers (meta-RR = 2.00; 95% CI, 1.09-3.67; 3 studies) and persisted when restricted to studies that adjusted for other occupational exposures (meta-RR = 1.57; 95% CI, 1.21-2.04; 5 studies). These results support the conclusion that occupational exposures in painters are causally associated with the risk of lung cancer.
authors.affiliation: Department of Biomedical Sciences and Human Oncology, University of Turin, Turin, Italy. guhan@iarc.fr
authors.forename: Neela
authors.initials: N
authors.lastname: Guha
authors.forename: Franco
authors.initials: F
authors.lastname: Merletti
authors.forename: Nelson Kyle
authors.initials: NK
authors.lastname: Steenland
authors.forename: Andrea
authors.initials: A
authors.lastname: Altieri
authors.forename: Vincent
authors.initials: V
authors.lastname: Cogliano
authors.forename: Kurt
authors.initials: K
authors.lastname: Straif
mesh_terms: D006801:Humans; D015994:Incidence; D008175:Lung Neoplasms / Q000453:epidemiology* / Q000401:mortality; D009784:Occupational Diseases / Q000453:epidemiology* / Q000401:mortality; D016273:Occupational Exposure / Q000009:adverse effects* / Q000706:statistics & numerical data*; D010150:Paint / Q000009:adverse effects*; D012307:Risk Factors