title: [Role of vascular endothelial growth factor and monocyte chemoattractant protein-1 in the development of endothelial dysfunction in types 1 and 2 diabetes mellitus complicated by diabetic retinopathy].
abstract: The paper presents the results of a study of the serum levels of monocyte chemoattractant protein-1 (MCP-1) and vascular endothelial growth factor (VEGF) in 120 patients with types 1 and 2 diabetes mellitus complicated by diabetic retinopathy. All the patients with diabetes have been ascertained to show a rise in the levels of MCP-1 and VEGF. Calculation of VEGF/MCP-1 ratio is proposed to evaluate vascular bed lesion in diabetic patients.
authors.forename: V V
authors.initials: VV
authors.lastname: Nikitina
authors.forename: N B
authors.initials: NB
authors.lastname: Zakharova
authors.forename: T G
authors.initials: TG
authors.lastname: Kamenskikh
mesh_terms: D000293:Adolescent; D000328:Adult; D018932:Chemokine CCL2 / Q000097:blood*; D003922:Diabetes Mellitus, Type 1 / Q000150:complications*; D003924:Diabetes Mellitus, Type 2 / Q000150:complications*; D003930:Diabetic Retinopathy / Q000097:blood* / Q000209:etiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D042461:Vascular Endothelial Growth Factor A / Q000097:blood*
chemical_list: C111835:CCL2 protein, human; D018932:Chemokine CCL2; D042461:Vascular Endothelial Growth Factor A