title: Provocative lumbar discography versus functional anesthetic discography: a comparison of the results of two different diagnostic techniques in 52 patients with chronic low back pain.
abstract: BACKGROUND
  There is mounting evidence that the currently available techniques for the diagnosis of discogenic low back pain are insufficiently accurate-this may explain some of the variability in outcomes of surgery for this important clinical problem. New diagnostic methods are needed to address this diagnostic issue; improvements here may do as much to improve overall patient outcomes as improvements in surgical treatment methods.
  
  
  OBJECTIVE
  To compare the results of standard pressure-controlled provocative discography (PD) to those of the functional anesthetic discogram (FAD) in a series of patients presenting with chronic low back pain and considering surgical treatment.
  
  
  METHODS
  Prospective clinical series in an academic spinal surgical practice.
  
  
  METHODS
  Fifty-two patients presenting with chronic low back pain; mean age 45 years (range, 24-70 years); 28 women, 24 men; and 25% in workman's compensation program.
  
  
  METHODS
  Oswestry, visual analog scale for back pain, distress and risk assessment method psychometric analysis, demographic data, magnetic resonance imaging scan of lumbar spine. During provocative discogram: pressurization at pain, pain level, and concordancy. During FAD: position or activity used to elicit typical pain, baseline pain level before injection, during injection, at 5, 10, and 20 minutes after the injection, and substance injected.
  
  
  METHODS
  Standard pressure-controlled PD was performed, followed by (in positive cases or in patients with clinical features and imaging studies felt to be highly suggestive of symptomatic disc degeneration) the FAD test-an assessment of the response to injection of a low dose of local anesthetic into the disc during a position productive of the patient's typical pain.
  
  
  RESULTS
  Discordant results of the two tests were noted in 46% of the patients in the series. Of them, 26% of patients with positive PD had negative findings on the FAD test; 16% had positive findings at a single level only, whereas the provocative discogram had been positive at two or more levels; 4% had new positive findings on the FAD test.
  
  
  CONCLUSIONS
  We have presented the results of a new diagnostic technique in 52 patients with chronic low back pain presumed discogenic in origin that was designed to help differentiate between symptomatic and asymptomatic disc degeneration. The findings of the test differed from those of standard pressure-controlled PD in 46% of the cases reported on here. Further studies are needed to demonstrate the clinical utility of the test.
authors.affiliation: Department of Orthopaedic Surgery, Stanford University School of Medicine, Room R-171, 300 Pasteur Drive, Stanford, CA 94305, USA. tfalamin@stanford.edu
authors.forename: Todd F
authors.initials: TF
authors.lastname: Alamin
authors.forename: Mi J
authors.initials: MJ
authors.lastname: Kim
authors.forename: Vijay
authors.initials: V
authors.lastname: Agarwal
mesh_terms: D000328:Adult; D000368:Aged; D000779:Anesthetics, Local; D002908:Chronic Disease; D003287:Contrast Media; D005260:Female; D006801:Humans; D017116:Low Back Pain / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D009192:Myelography / Q000379:methods*; D010147:Pain Measurement; D055815:Young Adult
chemical_list: D000779:Anesthetics, Local; D003287:Contrast Media