title: The impact of Haemophilus influenzae serotype B resurgence on the epidemiology of childhood invasive Haemophilus influenzae disease in England and Wales.
abstract: This study describes the epidemiology of childhood invasive Haemophilus influenzae disease in England and Wales between 1994 and 2008. H. influenzae serotype b incidence was lowest in 1998 (0.26/100,000), rising to 1.8/100,000 in 2002 before falling to 0.27/100,000 in 2008. During this period, nontype b H. influenzae disease remained stable, but there was a small year-on-year increase (3.4%/y; 95% CI: 1.4-5.5%) in incidence.
authors.affiliation: Immunisation Department, Centre for Infections, Health Protection Agency, London, England. shamez.ladhani@hpa.org.uk
authors.forename: Shamez N
authors.initials: SN
authors.lastname: Ladhani
authors.forename: Mary
authors.initials: M
authors.lastname: Ramsay
authors.forename: Mary P E
authors.initials: MP
authors.lastname: Slack
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D004739:England / Q000453:epidemiology; D005260:Female; D006193:Haemophilus influenzae / Q000145:classification* / Q000302:isolation & purification; D006801:Humans; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008583:Meningitis, Haemophilus / Q000453:epidemiology* / Q000382:microbiology*; D012703:Serotyping; D014852:Wales / Q000453:epidemiology