title: Polyphenol-rich strawberry pomace reduces serum and liver lipids and alters gastrointestinal metabolite formation in fructose-fed rats.
abstract: This study compared the effects of supplementation with a polyphenol-rich pomace from strawberry (US) and a strawberry pomace without most of these compounds (PS) on gastrointestinal, blood, and tissue biomarkers in rats fed diets differing in carbohydrate contents for 4 wk. The diets were: corn starch (group CS), high fructose (60% by weight; group F), starch with 7.7% of either US or PS (groups CS+US and CS+PS, respectively), and high fructose with 7.7% of either US or PS (groups F+US and F+PS, respectively). An interaction (P < 0.05) was observed between diet type and strawberry preparation, showing that upon fructose feeding, US had a greater effect than PS on lowering serum insulin, liver total cholesterol, and conjugated dienes. Additionally, the F+US group had lower serum FFA than the F+PS group (P < 0.05). The extraction of polyphenols diminished the physiological effect associated with strawberry intake, suggesting that the fiber component of the pomace was also active in reducing metabolic complications following fructose feeding to rats.
authors.affiliation: Division of Food Science, Institute of Animal Reproduction and Food Research, Polish Academy of Science, Olsztyn, Poland. j.jaroslawska@pan.olsztyn.pl
authors.forename: Julia
authors.initials: J
authors.lastname: Jaroslawska
authors.forename: Jerzy
authors.initials: J
authors.lastname: Juskiewicz
authors.forename: Monika
authors.initials: M
authors.lastname: Wroblewska
authors.forename: Adam
authors.initials: A
authors.lastname: Jurgonski
authors.forename: Boguslaw
authors.initials: B
authors.lastname: Krol
authors.forename: Zenon
authors.initials: Z
authors.lastname: Zdunczyk
mesh_terms: D000818:Animals; D015415:Biomarkers / Q000097:blood / Q000378:metabolism; D005511:Food Handling; D005525:Food-Processing Industry / Q000191:economics; D031985:Fragaria / Q000737:chemistry; D005632:Fructose / Q000009:adverse effects; D005638:Fruit / Q000737:chemistry; D041981:Gastrointestinal Tract / Q000378:metabolism*; D006949:Hyperlipidemias / Q000517:prevention & control; D007220:Industrial Waste / Q000032:analysis / Q000191:economics; D007333:Insulin Resistance; D015227:Lipid Peroxidation; D008055:Lipids / Q000097:blood*; D008099:Liver / Q000378:metabolism*; D008297:Male; D024821:Metabolic Syndrome / Q000517:prevention & control*; D059808:Polyphenols / Q000032:analysis / Q000627:therapeutic use*; D011897:Random Allocation; D051381:Rats; D017208:Rats, Wistar
chemical_list: D015415:Biomarkers; D007220:Industrial Waste; D008055:Lipids; D059808:Polyphenols; D005632:Fructose