title: Surgical strategies for management of the open abdomen.
abstract: Since the mid-1990s the surgical community has seen a surge in the prevalence of open abdomens (OAs) reported in the surgical literature and in clinical practice. The OA has proven to be effective in decreasing mortality and immediate postoperative complications; however, it may come at the cost of delayed morbidity and the need for further surgical procedures. Indications for leaving the abdomen open have broadened to include damage control surgery, abdominal compartment syndrome, and abdominal sepsis. The surgical options for management of the OA are now more diverse and sophisticated, but there is a lack of prospective randomized controlled trials demonstrating the superiority of any particular method. Additionally, critical care strategies for optimization of the patient with an OA are still being developed. Review of the literature suggests a bimodal distribution of primary closure rates, with early closure dependent on postoperative intensive care management and delayed closure more affected by the choice of the temporary abdominal closure technique. Invariably, a small fraction of patients requiring OA management fail to have primary fascial closure and require some form of biologic fascial bridge with delayed ventral hernia repair in the future.
authors.affiliation: Division of Trauma, Surgical Critical Care, and Burns, Department of Surgery, University of California, San Diego, 200 West Arbor Drive, #8896, San Diego, CA 92103-8896, USA.
authors.forename: Justin L
authors.initials: JL
authors.lastname: Regner
authors.forename: Leslie
authors.initials: L
authors.lastname: Kobayashi
authors.forename: Raul
authors.initials: R
authors.lastname: Coimbra
mesh_terms: D034861:Abdominal Wall / Q000601:surgery*; D058107:Abdominal Wound Closure Techniques; D013505:Digestive System Surgical Procedures / Q000379:methods / Q000639:trends*; D004750:Enteral Nutrition; D000071938:Fasciotomy; D006801:Humans; D007813:Laparotomy; D054843:Negative-Pressure Wound Therapy; D012307:Risk Factors