title: Regenerative endodontic treatment (revascularization) of immature necrotic molars medicated with calcium hydroxide: a case series.
abstract: BACKGROUND
  Revascularization is an emerging regenerative treatment protocol with little published data available in immature molar teeth. The present case series demonstrates the outcome of revascularization treatment with intracanal medicament of calcium hydroxide in immature necrotic molars.
  
  
  METHODS
  Immature necrotic permanent first molars (n = 6) of patients 8-11 years old were treated by a revascularization protocol that used 2.5% NaOCl irrigation, medication with calcium hydroxide placed in the coronal third of the root canals, induction of apical bleeding, and coronal sealing with white mineral trioxide aggregate. Among the treated teeth, 4 molars had undergone prior root canal instrumentation by the referring dentists. National Institutes of Health Image-J program with TurboReg plug-in was used for standardization of the radiographs and to determine the increase in root length and root width.
  
  
  RESULTS
  After a follow-up period of 10 months, all teeth demonstrated radiographic evidence of complete periapical healing, progressive thickening of dentinal walls, and continued apical development in the absence of clinical symptoms. Two uninstrumented molars showed a positive response to cold testing at 9 months.
  
  
  CONCLUSIONS
  On the basis of a follow-up period of 10 months, the present cases demonstrate a favorable outcome of the revascularization procedure in immature necrotic molars by using calcium hydroxide medication in the coronal third of the root canals.
authors.affiliation: Department of Pediatric Dentistry, Faculty of Dentistry, Hacettepe University, Ankara, Turkey. zcehreli@gmail.com
authors.forename: Zafer C
authors.initials: ZC
authors.lastname: Cehreli
authors.forename: Beste
authors.initials: B
authors.lastname: Isbitiren
authors.forename: Sezgi
authors.initials: S
authors.lastname: Sara
authors.forename: Gizem
authors.initials: G
authors.lastname: Erbas
mesh_terms: D056624:Apexification / Q000379:methods*; D002126:Calcium Hydroxide / Q000627:therapeutic use; D002648:Child; D003782:Dental Pulp / Q000098:blood supply* / Q000000981:diagnostic imaging; D003790:Dental Pulp Necrosis / Q000628:therapy*; D005260:Female; D006801:Humans; D008297:Male; D008963:Molar; D018919:Neovascularization, Physiologic; D011859:Radiography; D012038:Regeneration; D012388:Root Canal Irrigants / Q000627:therapeutic use*; D012390:Root Canal Therapy / Q000379:methods*; D019227:Tooth Apex / Q000098:blood supply / Q000000981:diagnostic imaging / Q000254:growth & development*
chemical_list: D012388:Root Canal Irrigants; D002126:Calcium Hydroxide