title: Gene regulation in response to DNA damage.
abstract: To deal with different kinds of DNA damages, there are a number of repair pathways that must be carefully orchestrated to guarantee genomic stability. Many proteins that play a role in DNA repair are involved in multiple pathways and need to be tightly regulated to conduct the functions required for efficient repair of different DNA damage types, such as double strand breaks or DNA crosslinks caused by radiation or genotoxins. While most of the factors involved in DNA repair are conserved throughout the different kingdoms, recent results have shown that the regulation of their expression is variable between different organisms. In the following paper, we give an overview of what is currently known about regulating factors and gene expression in response to DNA damage and put this knowledge in context with the different DNA repair pathways in plants. This article is part of a Special Issue entitled: Plant gene regulation in response to abiotic stress.
authors.affiliation: Botanical Institute II, Karlsruhe Institute of Technology, Karlsruhe, Germany.
authors.forename: Anja
authors.initials: A
authors.lastname: Mannuss
authors.forename: Oliver
authors.initials: O
authors.lastname: Trapp
authors.forename: Holger
authors.initials: H
authors.lastname: Puchta
mesh_terms: D004249:DNA Damage; D004260:DNA Repair; D018506:Gene Expression Regulation, Plant; D010940:Plant Proteins / Q000235:genetics / Q000378:metabolism*; D010944:Plants / Q000235:genetics* / Q000378:metabolism
chemical_list: D010940:Plant Proteins