title: Quality control of plant food supplements.
abstract: It is essential to guarantee the safety of unprocessed plants and food supplements if consumers' health is to be protected. Although botanicals and their preparations are regulated at EU level, at least in part, there is still considerable discretion at national level, and Member States may choose to classify a product either as a food supplement or as a drug. Accurate data concerning the finished products and the plant used as the starting point are of major importance if risks and safety are to be properly assessed, but in addition standardized criteria for herbal preparation must be laid down and respected by researchers and manufacturers. Physiologically active as well as potentially toxic constituents need to be identified, and suitable analytical methods for their measurement specified, particularly in view of the increasing incidence of economically motivated adulteration of herbal raw materials and extracts. It remains the duty of food operators to keep up with the scientific literature and to provide sufficient information to enable the adaptation of specifications, sampling schemes and analytical methods to a fast-changing environment.
authors.affiliation: Dept. Veterinary Public Health and Food Safety, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161, Rome, Italy. elisabetta.sanzini@iss.it
authors.forename: Elisabetta
authors.initials: E
authors.lastname: Sanzini
authors.forename: Mihaela
authors.initials: M
authors.lastname: Badea
authors.forename: Ariana Dos
authors.initials: AD
authors.lastname: Santos
authors.forename: Patrizia
authors.initials: P
authors.lastname: Restani
authors.forename: Hartwig
authors.initials: H
authors.lastname: Sievers
mesh_terms: D000383:Agriculture / Q000379:methods; D019587:Dietary Supplements / Q000009:adverse effects / Q000145:classification; D004365:Drugs, Chinese Herbal / Q000009:adverse effects / Q000737:chemistry; D005062:European Union; D005506:Food Contamination / Q000331:legislation & jurisprudence / Q000517:prevention & control; D006801:Humans; D007880:Legislation, Drug; D007881:Legislation, Food; D019216:Metals, Heavy / Q000032:analysis; D009183:Mycotoxins / Q000032:analysis; D010573:Pesticide Residues / Q000032:analysis; D028321:Plant Preparations / Q000009:adverse effects / Q000737:chemistry; D010945:Plants, Edible / Q000009:adverse effects / Q000737:chemistry / Q000145:classification; D011786:Quality Control
chemical_list: D004365:Drugs, Chinese Herbal; D019216:Metals, Heavy; D009183:Mycotoxins; D010573:Pesticide Residues; D028321:Plant Preparations