title: [Comparison of echocardiographic findings in AVS patients with and without high IgG, IgM, IgA titers against Chlamydia pneumoniae during 12 months' observation of AVS natural course].
abstract: OBJECTIVE
  Comparison of echocardiographic findings in AVS patients with and without high IgG, IgM, IgA titers against Chlamydia pneumoniae during 12 months' observation of AVS natural course.
  
  
  METHODS
  60 AVS patients who did not agree for operational treatment were divided into group A (30 patients with high IgG titer) group B (30 patients with low IgG titer), group C (22 patients with high IgA titer) group D (38 patients with low IgA titer), group E (7 patients with high IgM titer), group F (53 patients with low IgA titer) Antibodies titers and echocardiographic scans were carried out every 12 months.
  
  
  RESULTS
  There were more (p < 0.02) patients with AVS deterioration in group A compared to group B. Group A patients had lower left ventricle posteriori wall systolic diameter compared to group B. There were no differences in echocardiographic parameters between group C and D. Mean ejection fraction was lower and mean right atrium diameter was higher in group E compared to group F.
  
  
  CONCLUSIONS
  The results may suggest link between Chlamydia pneumoniae and deterioration of AVS.
authors.affiliation: II Klinika Kardiologii Collegium Medicum, Uniwersytetu Jagiellońskiego. grasshoppers@interia.eu
authors.forename: Jolanta
authors.initials: J
authors.lastname: Swierszcz
authors.forename: Jacek S
authors.initials: JS
authors.lastname: Dubiel
authors.forename: Józef
authors.initials: J
authors.lastname: Krzysiek
authors.forename: Krystyna
authors.initials: K
authors.lastname: Sztefko
authors.forename: Danuta
authors.initials: D
authors.lastname: Galicka-Latała
authors.forename: Pfitzner
authors.initials: P
authors.lastname: Roman
authors.forename: Piotr
authors.initials: P
authors.lastname: Podolec
authors.forename: Jan
authors.initials: J
authors.lastname: Wodniecki
mesh_terms: D000328:Adult; D000368:Aged; D001024:Aortic Valve Stenosis / Q000000981:diagnostic imaging* / Q000276:immunology*; D016993:Chlamydophila pneumoniae / Q000276:immunology*; D018450:Disease Progression; D004452:Echocardiography; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000097:blood*; D007074:Immunoglobulin G / Q000097:blood*; D007075:Immunoglobulin M / Q000097:blood*; D008297:Male; D008875:Middle Aged
chemical_list: D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M