title: Game changers: why did the scale-up of HIV treatment work despite weak health systems?
abstract: Game changers are radical innovations that result in fundamental and durable changes. The global HIV program scale-up witnessed over the past decade has included some innovations that are not well appreciated. The willingness to rapidly adopt and implement innovations, the flexibility and speed of program implementation, and the readiness to re-examine professional roles are just a few of such game changers. However, moving ahead, further work is needed to enhance the quality of programs, to energetically tackle HIV prevention, to build on this success, and to address other health threats that these same communities face.
authors.affiliation: Center for Global Health, US Center for Disease Control and Prevention, 1600 Clifton Road, Atlanta, GA 30333, USA. kmd2@cdc.gov
authors.forename: Kevin M
authors.initials: KM
authors.lastname: De Cock
authors.forename: Wafaa M
authors.initials: WM
authors.lastname: El-Sadr
authors.forename: Tedros A
authors.initials: TA
authors.lastname: Ghebreyesus
mesh_terms: D019380:Anti-HIV Agents / Q000191:economics / Q000627:therapeutic use; D003695:Delivery of Health Care / Q000191:economics* / Q000706:statistics & numerical data; D003906:Developing Countries / Q000191:economics / Q000706:statistics & numerical data; D005380:Financing, Government / Q000191:economics / Q000706:statistics & numerical data; D015658:HIV Infections / Q000188:drug therapy / Q000191:economics* / Q000453:epidemiology / Q000635:transmission; D006301:Health Services Needs and Demand / Q000191:economics / Q000706:statistics & numerical data; D006801:Humans; D007391:International Cooperation; D011634:Public Health / Q000191:economics / Q000706:statistics & numerical data
chemical_list: D019380:Anti-HIV Agents