title: [The role of magnesium in the implementation of vascular reactions during anesthesia in cardiac surgery patients].
abstract: The purpose of the study is to examine the relationship between the concentration of magnesium in plasma and vascular reactions during cardiac surgery.
  
  
  METHODS
  The study included 77 patients with coronary artery disease who underwent myocardial revascularization surgery. In the first group (n = 44) during the entire operation infusion solution "potassium and magnesium asparginate" (Berlin-Chemie) was carried out at a rate of 1.5-2 ml/kg/h, in the second group (n = 33) patients were injected magnesium free crystalloid solutions. An analysis of central hemodynamics (PiCCO Plus) and microcirculation (laser Doppler flowmetry LASMA) was carried out.
  
  
  CONCLUSIONS
  Maintenance of normal concentrations of magnesium in blood plasma reduces the incidence of episodes of intraoperative hypertension and improves peripheral microcirculation.
authors.forename: B A
authors.initials: BA
authors.lastname: Aksel'rod
authors.forename: I A
authors.initials: IA
authors.lastname: Tolstova
authors.forename: M Iu
authors.initials: MIu
authors.lastname: Andrianova
authors.forename: N A
authors.initials: NA
authors.lastname: Trekova
mesh_terms: D000328:Adult; D000368:Aged; D000768:Anesthesia, General; D002316:Cardiotonic Agents / Q000008:administration & dosage / Q000097:blood* / Q000627:therapeutic use; D000077324:Crystalloid Solutions; D005112:Extracorporeal Circulation; D005260:Female; D006439:Hemodynamics / Q000187:drug effects*; D006801:Humans; D006973:Hypertension / Q000517:prevention & control; D007431:Intraoperative Complications / Q000517:prevention & control; D007552:Isotonic Solutions; D008274:Magnesium / Q000008:administration & dosage / Q000097:blood* / Q000627:therapeutic use; D008297:Male; D008833:Microcirculation / Q000187:drug effects; D008875:Middle Aged; D009204:Myocardial Revascularization / Q000379:methods*; D011195:Potassium Magnesium Aspartate / Q000008:administration & dosage / Q000097:blood / Q000627:therapeutic use; D016896:Treatment Outcome
chemical_list: D002316:Cardiotonic Agents; D000077324:Crystalloid Solutions; D007552:Isotonic Solutions; D011195:Potassium Magnesium Aspartate; D008274:Magnesium