title: Combined effects of whole-body vibration, resistance exercise, and vascular occlusion on skeletal muscle and performance.
abstract: The purpose of this study was to evaluate the effects of a new high-intensity training modality comprised of vibration exercise with superimposed resistance exercise and vascular occlusion (vibroX) on skeletal muscle and performance. Young untrained women were randomized to either train in a progressive mode on 3 days per week for 5 weeks ( N=12) or to maintain a sedentary lifestyle ( N=9). VibroX increased peak cycling power (+9%, P=0.001), endurance capacity (+57%, P=0.002), ventilatory threshold (+12%, P<0.001), and end-test torque (+15%, P=0.002) relative to the sedentary group. Training load increased by 84.5% ( P<0.001) after vibroX. The increases were paralleled by increases in myosin heavy chain type 1 vastus lateralis muscle fiber cross-sectional area (+14%, P=0.031) and proportion (+17%, P=0.015), thigh lean mass (+4%, P=0.001), capillary-to-fiber ratio (+14%, P=0.003), and cytochrome c oxidase activity. Conversely, maximal values for oxygen consumption, cardiac output, isokinetic leg extension power and jumping power remained unaffected. Notably, vastus lateralis muscle adaptations were achieved with a very low weekly training volume. We conclude that vibroX quickly increases muscle (fiber) size, capillarization, and oxidative potential, and markedly augments endurance capacity in young women.
authors.affiliation: Exercise Physiology, Institute of Human Movement Sciences and Sport, ETH Zurich, Switzerland.
authors.forename: F
authors.initials: F
authors.lastname: Item
authors.forename: J
authors.initials: J
authors.lastname: Denkinger
authors.forename: P
authors.initials: P
authors.lastname: Fontana
authors.forename: M
authors.initials: M
authors.lastname: Weber
authors.forename: U
authors.initials: U
authors.lastname: Boutellier
authors.forename: M
authors.initials: M
authors.lastname: Toigo
mesh_terms: D000328:Adult; D001642:Bicycling / Q000502:physiology*; D002302:Cardiac Output / Q000502:physiology; D003576:Electron Transport Complex IV / Q000378:metabolism; D015444:Exercise / Q000502:physiology*; D005260:Female; D006801:Humans; D018485:Muscle Fibers, Skeletal / Q000502:physiology; D018482:Muscle, Skeletal / Q000502:physiology*; D018995:Myosin Heavy Chains / Q000378:metabolism; D010101:Oxygen Consumption / Q000502:physiology; D010807:Physical Endurance / Q000502:physiology*; D052097:Quadriceps Muscle / Q000502:physiology; D055070:Resistance Training / Q000379:methods; D019415:Torque; D014732:Vibration; D055815:Young Adult
chemical_list: D003576:Electron Transport Complex IV; D018995:Myosin Heavy Chains