title: Resonance scattering particles as biological nanosensors in vitro and in vivo.
abstract: Recently dark-field microscopy and Rayleigh scattering spectroscopy have emerged as complementary technologies for ultrasensitive biological detection and imaging with high spatial and temporal resolution. Plasmonic resonant nanoparticles are key nano-scale probes for these technologies that have enabled single-molecule sensitivity and imaging. In this tutorial review, we focus on the use of plasmonic probes as single-particle biological nanosensors in vitro and in vivo. The progress in this field over the last decade will be highlighted.
authors.affiliation: Shanghai Key Laboratory of Functional Materials Chemistry & Department of Chemistry, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, P. R. China.
authors.forename: Yang
authors.initials: Y
authors.lastname: Li
authors.forename: Chao
authors.initials: C
authors.lastname: Jing
authors.forename: Lei
authors.initials: L
authors.lastname: Zhang
authors.forename: Yi-Tao
authors.initials: YT
authors.lastname: Long
mesh_terms: D000682:Amyloid / Q000737:chemistry; D000818:Animals; D015374:Biosensing Techniques; D004735:Energy Transfer; D006801:Humans; D053758:Nanoparticles / Q000737:chemistry*; D009369:Neoplasms / Q000473:pathology; D009842:Oligopeptides / Q000378:metabolism; D020349:Surface Plasmon Resonance
chemical_list: D000682:Amyloid; D009842:Oligopeptides; C047981:arginyl-glycyl-aspartic acid