title: Primary acinic cell carcinoma of the breast: a case report with an immunohistochemical and ultrastructural studies.
abstract: Acinic cell carcinoma (ACC) of the breast is extremely rare and is characterized by widespread acinar cell-like differentiation. We report of a 39-year-old woman presented with a palpable breast mass with significant morphological, immunohistochemical and ultrastructural findings. Histologically, ACC showed a diffuse glandular infiltrative pattern, with small acinar or glandular structures mixed with solid nests. Neoplastic cells were monotonous proliferation of cells with a granular or clear cytoplasm, resembling acinar cells of the salivary glands or Paneth cells. Both glandular and solid tumor cell populations were strongly positive for lysozyme and α-1-antitrypsin.
authors.affiliation: Department of Pathology, The Catholic University of Korea College of Medicine, Seoul, Korea.
authors.forename: Eun Deok
authors.initials: ED
authors.lastname: Chang
authors.forename: Eun Jung
authors.initials: EJ
authors.lastname: Lee
authors.forename: Ah Won
authors.initials: AW
authors.lastname: Lee
authors.forename: Jeong Soo
authors.initials: JS
authors.lastname: Kim
authors.forename: Chang Suk
authors.initials: CS
authors.lastname: Kang