title: Laparoscopic radical prostatectomy: oncological and functional outcomes of 559 cases in Siriraj Hospital, Thailand.
abstract: OBJECTIVE
  To evaluate the results of oncological and functional outcomes of laparoscopic radical prostatectomy (LRP) during the first five years experience in Siriraj hospital.
  
  
  METHODS
  Between September 2004 and September 2009, the functional and oncological outcomes of 559 patients that underwent LRP were retrospectively evaluated.
  
  
  RESULTS
  The distribution of pathological T stage was T2 (52.1%), T3 (39.9%), and T4 (2.9%). Lymph node metastasis (N1) were found in 19 patients (3.4%). The positive margin rates in pT2a-b, pT2c, pT3a, pT3b and pT4 were 13.2%, 34.7%, 65.9%, 72.7% and 76.9%, respectively. The 3-year biological progression free survival (bPFS) rate for all patients was 87.2%. Three-year bPFS rates in pT2a-b, pT2c, pT3a, pT3b and pT4 were 96.3%, 93%, 75%, 55.6% and 62.5% respectively. The continent rate at 12 months was 84% and potency rate at 12 months in group that received bilateral nerve sparing was 29.1%.
  
  
  CONCLUSIONS
  The oncological and functional results of our first LRPs in Thai men are acceptable and compared well with the early experience of previous studies. However, longer follow up is needed for further evaluation.
authors.affiliation: Division of Urology, Department of Surgery, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand.
authors.forename: Phisaiphun
authors.initials: P
authors.lastname: Wattayang
authors.forename: Chaiyong
authors.initials: C
authors.lastname: Nualyong
authors.forename: Sunai
authors.initials: S
authors.lastname: Leewansangtong
authors.forename: Sittiporn
authors.initials: S
authors.lastname: Srinualnad
authors.forename: Tawatchai
authors.initials: T
authors.lastname: Taweemonkongsap
authors.forename: Bansithi
authors.initials: B
authors.lastname: Chaiyaprasithi
authors.forename: Teerapon
authors.initials: T
authors.lastname: Amornvesukit
authors.forename: Kittipong
authors.initials: K
authors.lastname: Phinthusophon
authors.forename: Siros
authors.initials: S
authors.lastname: Jitpraphai
authors.forename: Buncha
authors.initials: B
authors.lastname: Thiptirapong
authors.forename: Pichaya
authors.initials: P
authors.lastname: Sujijantararat
authors.forename: Suchai
authors.initials: S
authors.lastname: Soontrapa
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D007172:Erectile Dysfunction / Q000209:etiology; D005500:Follow-Up Studies; D006784:Hospitals, Teaching; D006801:Humans; D010535:Laparoscopy / Q000379:methods; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D011467:Prostate / Q000294:innervation* / Q000473:pathology / Q000601:surgery; D011468:Prostatectomy / Q000379:methods*; D011471:Prostatic Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D020127:Recovery of Function / Q000502:physiology; D012189:Retrospective Studies; D015996:Survival Rate; D013785:Thailand / Q000453:epidemiology; D016896:Treatment Outcome; D014549:Urinary Incontinence / Q000209:etiology