title: Bdellovibrios, potential biocontrol bacteria against pathogenic Aeromonas hydrophila.
abstract: Recent studies have revealed that the use of bdellovibrios is an alternative to control bacteriosis. However, no bdellovibrios are available against Aeromonas hydrophila infections in sturgeons. In the present study, a potential Bdellovibrio strain F16 was isolated from sturgeon gut samples, using a sturgeon-pathogenic A. hydrophila as the prey bacterium. It was initially identified as a Bdellovibrio strain using morphological characteristics and specific PCR amplification, and confirmed to be Bdellovibrio sp. strain ETB (GenBank Accession No. DQ302728) and Bdellovibrio bacteriovorus strain SRA9 (GenBank Accession No. AF263833) by phylogenetic analysis. In addition, it was shown to be safe for mammalians and sturgeons, had a wide prey range, and exhibited significant bacteriolytic effects on the pathogenic A. hydrophila. To the best of our knowledge, this is the first report on a promising gut Bdellovibrio strain against pathogenic A. hydrophila.
authors.affiliation: Key Laboratory of Exploration and Utilization of Aquatic Genetic Resources of Ministry of Education, National Pathogen Collection Center for Aquatic Animals, Shanghai Ocean University, Shanghai 201306, PR China.
authors.forename: Haipeng
authors.initials: H
authors.lastname: Cao
authors.forename: Shan
authors.initials: S
authors.lastname: He
authors.forename: Huicong
authors.initials: H
authors.lastname: Wang
authors.forename: Sanling
authors.initials: S
authors.lastname: Hou
authors.forename: Liqun
authors.initials: L
authors.lastname: Lu
authors.forename: Xianle
authors.initials: X
authors.lastname: Yang
mesh_terms: D016980:Aeromonas hydrophila / Q000145:classification / Q000235:genetics / Q000472:pathogenicity / Q000502:physiology*; D000818:Animals; D000898:Antibiosis; D001419:Bacteria / Q000235:genetics; D001501:Bdellovibrio / Q000145:classification / Q000235:genetics / Q000502:physiology*; D061046:Biological Control Agents; D005393:Fish Diseases / Q000382:microbiology; D016905:Gram-Negative Bacterial Infections / Q000382:microbiology / Q000662:veterinary; D010802:Phylogeny; D016133:Polymerase Chain Reaction
chemical_list: D061046:Biological Control Agents