title: Autologous biologic treatment for equine musculoskeletal injuries: platelet-rich plasma and IL-1 receptor antagonist protein.
abstract: Autologous biologic therapies such as platelet-rich plasma and autologous conditioned serum are in widespread clinical use to treat musculoskeletal pathology in horses. These substances exert a therapeutic effect through the provision of either anabolic or anti-catabolic factors, or a combination of both. This article discusses the history, experimental and clinical literature, and currently accepted preparation and usage strategies for both platelet-rich plasma and autologous conditioned serum.
authors.affiliation: Tablin Laboratory, Department of Pathology, Microbiology and Immunology, College of Veterinary Medicine, University of California Davis, VM3A 4318, 1 Shields Avenue, Davis, CA 95616, USA. jamietextor@gmail.com
authors.forename: Jamie
authors.initials: J
authors.lastname: Textor
mesh_terms: D000818:Animals; D006734:Horse Diseases / Q000209:etiology / Q000628:therapy*; D006736:Horses / Q000293:injuries*; D053590:Interleukin 1 Receptor Antagonist Protein / Q000191:economics / Q000627:therapeutic use*; D008022:Ligaments / Q000293:injuries; D009141:Musculoskeletal System / Q000293:injuries*; D053657:Platelet-Rich Plasma; D012421:Rupture / Q000628:therapy / Q000662:veterinary; D013708:Tendon Injuries / Q000628:therapy / Q000662:veterinary
chemical_list: D053590:Interleukin 1 Receptor Antagonist Protein