title: Network reconfiguration and neuronal plasticity in rhythm-generating networks.
abstract: Neuronal networks are highly plastic and reconfigure in a state-dependent manner. The plasticity at the network level emerges through multiple intrinsic and synaptic membrane properties that imbue neurons and their interactions with numerous nonlinear properties. These properties are continuously regulated by neuromodulators and homeostatic mechanisms that are critical to maintain not only network stability and also adapt networks in a short- and long-term manner to changes in behavioral, developmental, metabolic, and environmental conditions. This review provides concrete examples from neuronal networks in invertebrates and vertebrates, and illustrates that the concepts and rules that govern neuronal networks and behaviors are universal.
authors.affiliation: Center for Integrative Brain Research, Seattle Children's Research Institute, 1900 9th Street, Seattle, WA 98101, USA.
authors.forename: Henner
authors.initials: H
authors.lastname: Koch
authors.forename: Alfredo J
authors.initials: AJ
authors.lastname: Garcia
authors.forename: Jan-Marino
authors.initials: JM
authors.lastname: Ramirez
mesh_terms: D000818:Animals; D001522:Behavior, Animal; D006706:Homeostasis; D007448:Invertebrates / Q000502:physiology*; D009415:Nerve Net / Q000502:physiology*; D009433:Neural Inhibition; D009434:Neural Pathways / Q000502:physiology; D009473:Neuronal Plasticity; D009474:Neurons / Q000502:physiology*; D010507:Periodicity; D055366:Synaptic Potentials; D009435:Synaptic Transmission; D014714:Vertebrates / Q000502:physiology*