title: Acquired hemophilia A.
abstract: Acquired hemophilia A is a rare but often life-threatening hemorrhagic disorder characterized by an autoantibody directed against coagulation factor VIII. Fifty per cent of cases are idiopathic whereas the remaining 50% are associated with pregnancy, autoimmune conditions, malignancies and drugs. In this review the actual knowledge on diagnostic and therapeutic aspects of this disease will be summarized.
authors.affiliation: Department of Pathology and Laboratory Medicine, Immunohematology and Transfusion Center, University Hospital of Parma, Parma, Italy mfranchini@ao.pr.it
authors.forename: Massimo
authors.initials: M
authors.lastname: Franchini
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Lippi
mesh_terms: D000818:Animals; D006467:Hemophilia A / Q000175:diagnosis / Q000209:etiology / Q000628:therapy*; D006801:Humans