title: Do defense styles of ego relate to volumes of orbito-frontal cortex in patients with obsessive-compulsive disorder?
abstract: OBJECTIVE
  Although the importance of orbito-frontal cortex (OFC) is established in the pathogenesis of obsessive compulsive disorder (OCD), no study have evaluated its relation to the traditional psychodynamic perspective. In the present study, we aimed to evaluate the relationship between the defense styles consisting of mature, immature and neurotic defenses and OFC volumes of patients with OCD.
  
  
  METHODS
  Subjects were selected among those of our previous study, and so eighteen patients with OCD and same number of healthy controls were took into the study. The patients and controls had underwent magnetic resonance imaging (MRI). In addition, the Defense Style Questionnaire-40 was administered to obtain defense styles of patients and controls.
  
  
  RESULTS
  No significant relationship was found between the right OFC volumes of both the patient and control groups and their scores of mature, neurotic, or immature defense mechanisms. As for the left OFC volumes, the only significant relationship for the scores of immature defense mechanism was found in the patient group.
  
  
  CONCLUSIONS
  The results of the present study indicated that there was no significant relationship between OFC volumes of the patient group and their scores of mature, neurotic, or immature defense mechanisms, except a significant relation with the scores of immature defense mechanisms.
authors.affiliation: Department of Psychiatry, School of Medicine, Firat University, Elazig, Turkey.
authors.forename: Murad
authors.initials: M
authors.lastname: Atmaca
authors.forename: Hanefi
authors.initials: H
authors.lastname: Yildirim
authors.forename: Mustafa
authors.initials: M
authors.lastname: Koc
authors.forename: Sevda
authors.initials: S
authors.lastname: Korkmaz
authors.forename: Sinan
authors.initials: S
authors.lastname: Ozler
authors.forename: Zehra
authors.initials: Z
authors.lastname: Erenkus