title: Spectrin-based skeleton as an actor in cell signaling.
abstract: This review focuses on the recent advances in functions of spectrins in non-erythroid cells. We discuss new data concerning the commonly known role of the spectrin-based skeleton in control of membrane organization, stability and shape, and tethering protein mosaics to the cellular motors and to all major filament systems. Particular effort has been undertaken to highlight recent advances linking spectrin to cell signaling phenomena and its participation in signal transduction pathways in many cell types.
authors.affiliation: University of Zielona Góra, Zielona Góra, Poland.
authors.forename: B
authors.initials: B
authors.lastname: Machnicka
authors.forename: R
authors.initials: R
authors.lastname: Grochowalska
authors.forename: D M
authors.initials: DM
authors.lastname: Bogusławska
authors.forename: A F
authors.initials: AF
authors.lastname: Sikorski
authors.forename: M C
authors.initials: MC
authors.lastname: Lecomte
mesh_terms: D000818:Animals; D029742:Caenorhabditis elegans Proteins / Q000235:genetics / Q000378:metabolism; D002448:Cell Adhesion; D018797:Cell Cycle Proteins / Q000378:metabolism; D003599:Cytoskeleton / Q000378:metabolism*; D029721:Drosophila Proteins / Q000235:genetics / Q000378:metabolism; D006801:Humans; D021962:Membrane Microdomains / Q000378:metabolism; D051379:Mice; D020033:Protein Isoforms / Q000235:genetics / Q000378:metabolism; D011499:Protein Processing, Post-Translational; D015398:Signal Transduction; D013049:Spectrin / Q000235:genetics / Q000378:metabolism*
chemical_list: D029742:Caenorhabditis elegans Proteins; D018797:Cell Cycle Proteins; D029721:Drosophila Proteins; D020033:Protein Isoforms; D013049:Spectrin