title: Facial melanoses: Indian perspective.
abstract: Facial melanoses (FM) are a common presentation in Indian patients, causing cosmetic disfigurement with considerable psychological impact. Some of the well defined causes of FM include melasma, Riehl's melanosis, Lichen planus pigmentosus, erythema dyschromicum perstans (EDP), erythrosis, and poikiloderma of Civatte. But there is considerable overlap in features amongst the clinical entities. Etiology in most of the causes is unknown, but some factors such as UV radiation in melasma, exposure to chemicals in EDP, exposure to allergens in Riehl's melanosis are implicated. Diagnosis is generally based on clinical features. The treatment of FM includes removal of aggravating factors, vigorous photoprotection, and some form of active pigment reduction either with topical agents or physical modes of treatment. Topical agents include hydroquinone (HQ), which is the most commonly used agent, often in combination with retinoic acid, corticosteroids, azelaic acid, kojic acid, and glycolic acid. Chemical peels are important modalities of physical therapy, other forms include lasers and dermabrasion.
authors.affiliation: Department of Dermatology and Venereology, All India Institute of Medical Sciences, New Delhi, India. neena_aiims@yahoo.co.in
authors.forename: Neena
authors.initials: N
authors.lastname: Khanna
authors.forename: Seemab
authors.initials: S
authors.lastname: Rasool
mesh_terms: D000287:Administration, Topical; D000818:Animals; D005148:Facial Dermatoses / Q000208:ethnology* / Q000473:pathology* / Q000628:therapy; D006801:Humans; D017495:Hyperpigmentation / Q000208:ethnology / Q000473:pathology / Q000628:therapy; D007641:Keratolytic Agents / Q000008:administration & dosage; D008548:Melanosis / Q000208:ethnology* / Q000473:pathology* / Q000628:therapy; D014212:Tretinoin / Q000008:administration & dosage; D014466:Ultraviolet Rays / Q000009:adverse effects
chemical_list: D007641:Keratolytic Agents; D014212:Tretinoin