title: The incidence of heterogeneous vancomycin-intermediate Staphylococcus aureus correlated with increase of vancomycin MIC.
abstract: A total of 559 methicillin-resistant Staphylococcus aureus isolates were investigated for heterogeneous vancomycin-intermediate S. aureus (hVISA) by population analysis profile area under the curve. Our results suggested that the incidence of hVISA increased rapidly when vancomycin MIC shifted from 1 to 2 μg/mL, and at vancomycin MIC of 2 μg/mL, the incidence of hVISA was nearly 40%.
authors.affiliation: Department of Clinical Laboratory, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, 100730, People's Republic of China.
authors.forename: Hongbin
authors.initials: H
authors.lastname: Chen
authors.forename: Yudong
authors.initials: Y
authors.lastname: Liu
authors.forename: Wenjia
authors.initials: W
authors.lastname: Sun
authors.forename: Minjun
authors.initials: M
authors.lastname: Chen
authors.forename: Hui
authors.initials: H
authors.lastname: Wang
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D006801:Humans; D015994:Incidence; D055624:Methicillin-Resistant Staphylococcus aureus / Q000187:drug effects* / Q000302:isolation & purification; D008826:Microbial Sensitivity Tests; D013203:Staphylococcal Infections / Q000453:epidemiology; D014640:Vancomycin / Q000494:pharmacology*; D020713:Vancomycin Resistance
chemical_list: D000900:Anti-Bacterial Agents; D014640:Vancomycin