title: Incidence and risk factors of intraoperative awareness during general anesthesia.
abstract: OBJECTIVE
  To investigate the incidence of awareness during general anesthesia and analyze the risk factors in anesthetic practice and patient populations.
  
  
  METHODS
  A total of 2 300 patients who underwent general anesthesia were included. Perioperative data and anesthetic drugs were collected prospectively. Patients were interviewed twice postoperatively with the same structured questionnaire. Each patient was classified into categories as no awareness, possible awareness, and awareness.
  
  
  RESULTS
  Twenty-one patients (0.91%) definitely reported awareness, and another 205 (8.91%) reported possible awareness. Few of the patients with awareness required psychological intervention. ASA physical status III-IV and propofol maintenance were associated risk factors of awareness.
  
  
  CONCLUSIONS
  The incidence of intraoperative awareness is high in the clinical practice in major medical centers.
authors.affiliation: Department of Anesthesiology, Xiangya Hospital, Central South University, Changsha 410008, China.
authors.forename: E
authors.initials: E
authors.lastname: Wang
authors.forename: Zhi
authors.initials: Z
authors.lastname: Ye
authors.forename: Yundan
authors.initials: Y
authors.lastname: Pan
authors.forename: Zongbin
authors.initials: Z
authors.lastname: Song
authors.forename: Changsheng
authors.initials: C
authors.lastname: Huang
authors.forename: Hui
authors.initials: H
authors.lastname: Luo
authors.forename: Qulian
authors.initials: Q
authors.lastname: Guo
mesh_terms: D000328:Adult; D000768:Anesthesia, General / Q000009:adverse effects*; D018686:Anesthetics, Intravenous / Q000009:adverse effects; D001364:Awareness; D002681:China / Q000453:epidemiology; D005260:Female; D006801:Humans; D015994:Incidence; D007431:Intraoperative Complications / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D015742:Propofol / Q000009:adverse effects; D012307:Risk Factors
chemical_list: D018686:Anesthetics, Intravenous; D015742:Propofol