title: TVT-O vs. TVT for the treatment of SUI: a non-inferiority study.
abstract: OBJECTIVE
  This study aimed to prospectively compare, in terms of efficacy and safety, the tension-free vaginal tape (TVT) and the transobturator vaginal tape inside-out (TVT-O) procedure for stress urinary incontinence.
  
  
  METHODS
  A cough stress test was applied to the objective outcomes, while urinary incontinence-specific quality of life questionnaire was applied to the subjective outcomes. A test for non-inferiority was carried out for detecting the success rate between the two groups.
  
  
  RESULTS
  The objective success rates were found to be 95.4% (62/65) in the TVT group and 96.4% (108/112) in the TVT-O group. No significant difference was found between these two groups in the success rate by non-inferiority test (P < 0.0005), with significant improvement in quality of life and no significant difference in patient satisfaction rates in the two groups (P > 0.05).
  
  
  CONCLUSIONS
  In the study, the TVT-O procedure could be defined to be identical to the TVT approach in success rate by non-inferiority test.
authors.affiliation: Department of Obstetrics and Gynecology, Tongji Hospital of Tongji University, 389 Xincun Rd., Shanghai, China.
authors.forename: Xiang
authors.initials: X
authors.lastname: Yang
authors.forename: Min
authors.initials: M
authors.lastname: Jiang
authors.forename: Xinliang
authors.initials: X
authors.lastname: Chen
authors.forename: Xiaowen
authors.initials: X
authors.lastname: Tong
authors.forename: Huaifang
authors.initials: H
authors.lastname: Li
authors.forename: Jin
authors.initials: J
authors.lastname: Qiu
authors.forename: Lingyun
authors.initials: L
authors.lastname: Shao
mesh_terms: D000368:Aged; D016063:Blood Loss, Surgical; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008875:Middle Aged; D017060:Patient Satisfaction; D011446:Prospective Studies; D011475:Prosthesis Failure; D011788:Quality of Life; D018709:Statistics, Nonparametric; D053825:Suburethral Slings / Q000009:adverse effects; D011795:Surveys and Questionnaires; D013997:Time Factors; D016896:Treatment Outcome; D001743:Urinary Bladder / Q000293:injuries; D014550:Urinary Incontinence, Stress / Q000601:surgery*; D016055:Urinary Retention / Q000209:etiology; D013520:Urologic Surgical Procedures / Q000009:adverse effects / Q000379:methods*