title: Dendron-mediated self-assembly of highly PEGylated block copolymers: a modular nanocarrier platform.
abstract: PEGylated dendron coils (PDCs) were investigated as a novel potential nanocarrier platform. PDCs self-assembled into micelles at lower CMCs than linear copolymer counterparts by 1-2 orders of magnitude, due to the unique architecture of dendrons. MD simulations also supported thermodynamically favourable self-assembly mediated by dendrons.
authors.affiliation: Department of Biopharmaceutical Sciences, University of Illinois at Chicago, 833 S. Wood St. Chicago, IL 60612, USA.
authors.forename: Jin Woo
authors.initials: JW
authors.lastname: Bae
authors.forename: Ryan M
authors.initials: RM
authors.lastname: Pearson
authors.forename: Niladri
authors.initials: N
authors.lastname: Patra
authors.forename: Suhair
authors.initials: S
authors.lastname: Sunoqrot
authors.forename: Lela
authors.initials: L
authors.lastname: Vuković
authors.forename: Petr
authors.initials: P
authors.lastname: Král
authors.forename: Seungpyo
authors.initials: S
authors.lastname: Hong
mesh_terms: D050091:Dendrimers / Q000737:chemistry*; D057927:Hydrophobic and Hydrophilic Interactions; D008823:Micelles; D008968:Molecular Conformation; D056004:Molecular Dynamics Simulation; D011092:Polyethylene Glycols / Q000737:chemistry*
chemical_list: D050091:Dendrimers; D008823:Micelles; D011092:Polyethylene Glycols