title: Oral misoprostol for the management of incomplete abortion in Ecuador.
abstract: OBJECTIVE
  To assess the feasibility of introducing misoprostol for the treatment of incomplete abortion in Quito, Ecuador.
  
  
  METHODS
  In a randomized prospective study conducted at a large tertiary-level maternity hospital and a private secondary-level clinic between November 2006 and November 2007, women with incomplete abortion were treated with either 600 μg of oral misoprostol (n=122) or manual vacuum aspiration (MVA) (n=120). All participants were requested to return for follow-up care on day 7 to determine the success of the treatment and to document their satisfaction with the method and the adverse effects experienced.
  
  
  RESULTS
  Sixteen percent of women (39/242) did not return for their follow-up visit and their outcomes are unknown. Among those who did return, 94% (100/106) of women showed successful completion of abortion after treatment with misoprostol, as compared with 100% (97/97) of women treated with MVA. Most women described their adverse effects after treatment as tolerable (misoprostol, 95%; MVA, 91%). Nearly all women reported being satisfied with their treatment (196/203); there were no differences among the women's reports of satisfaction according to treatment received.
  
  
  CONCLUSIONS
  An oral dose of 600 μg of misoprostol was found to be an acceptable and effective non-surgical option for treating incomplete abortion. Clinical trials.gov NCT00674232.
authors.affiliation: Hospital Gineco-Obstétrico Isidro Ayora, Quito, Ecuador.
authors.forename: Rolando
authors.initials: R
authors.lastname: Montesinos
authors.forename: Jill
authors.initials: J
authors.lastname: Durocher
authors.forename: Wilfrido
authors.initials: W
authors.lastname: León
authors.forename: Mónica
authors.initials: M
authors.lastname: Arellano
authors.forename: Melanie
authors.initials: M
authors.lastname: Peña
authors.forename: Ernesto
authors.initials: E
authors.lastname: Pinto
authors.forename: Beverly
authors.initials: B
authors.lastname: Winikoff
mesh_terms: D000020:Abortifacient Agents, Nonsteroidal / Q000008:administration & dosage / Q000627:therapeutic use*; D000027:Abortion, Incomplete / Q000188:drug therapy* / Q000601:surgery; D000284:Administration, Oral; D000328:Adult; D004484:Ecuador; D005260:Female; D006801:Humans; D008427:Maternal Health Services; D016595:Misoprostol / Q000008:administration & dosage / Q000627:therapeutic use*; D017060:Patient Satisfaction; D011247:Pregnancy; D011446:Prospective Studies; D014619:Vacuum Curettage
chemical_list: D000020:Abortifacient Agents, Nonsteroidal; D016595:Misoprostol