title: Ultrasound-promoted catalyst-free one-pot four component synthesis of 2H-indazolo[2,1-b]phthalazine-triones in neutral ionic liquid 1-butyl-3-methylimidazolium bromide.
abstract: A catalyst-free one-pot four component methodology for the synthesis of 2H-indazolo[2,1-b]phthalazine-triones under ultrasonic irradiation at room temperature using 1-butyl-3-methylimidazolium bromide, [Bmim]Br, as a neutral reaction medium is described. A broad range of structurally diverse aldehydes (aromatic aldehydes bearing electron withdrawing and/or electron releasing groups as well as heteroaromatic aldehydes) were applied successfully, and corresponding products were obtained in good to excellent yields without any byproduct.
authors.affiliation: College of Chemistry, Islamic Azad University, Bandar Abbas Branch, Hormozgan, Iran. arita@pharm.u-szeged.hu
authors.forename: Mohsen
authors.initials: M
authors.lastname: Shekouhy
authors.forename: Alireza
authors.initials: A
authors.lastname: Hasaninejad
mesh_terms: D060326:Chemistry Techniques, Synthetic / Q000379:methods*; D007093:Imidazoles / Q000737:chemistry*; D052578:Ionic Liquids / Q000737:chemistry*; D010793:Phthalazines / Q000138:chemical synthesis* / Q000737:chemistry*; D013696:Temperature; D014465:Ultrasonics
chemical_list: D007093:Imidazoles; D052578:Ionic Liquids; D010793:Phthalazines; C502841:1-butyl-3-methylimidazolium chloride; C043388:phthalazine