title: [Severe primary liver abscess and septic pulmonary embolism due to Klebsiella pneumoniae with hypermucoviscosity phenotype].
abstract: A 70-year-old man with diabetes mellitus seen for fever, right chest pain, and right-lung field consolidation on chest X-ray was found in thoracoabdominal computed tomography (CT) to have variable-sized nodules in both lung fields and multiple low-density hepatic areas. On physical examination, his pulse was 145 beats per minute and blood pressure 92/68mmHg, indicating a preshock state. Laboratory tests showed elevated WBC of 15,200/microL, serum-C-reactive protein (CRP) of 34.4 mg/dL, and a decreased platelet count of 16,000/microL. Suspecting liver abscesses complicated by a septic pulmonary embolism, we immediately conducted percutaneous transhepatic abscess drainage (PTAD). Liver abscess blood culture and drainage fluid grew the Klebsiella pneumoniae hypermucoviscosity phenotype, carrying the rmpA gene. Although the man had been in critical condition on admission, broad-spectrum antibiotics and PTAD treatment improved his clinical condition to where he could be discharged without problem.
authors.affiliation: Department of Respiratory Medicine, Kyorin University School of Medicine.
authors.forename: Keitaro
authors.initials: K
authors.lastname: Nakamoto
authors.forename: Takashi
authors.initials: T
authors.lastname: Koide
authors.forename: Tomoko
authors.initials: T
authors.lastname: Nagatomo
authors.forename: Masaki
authors.initials: M
authors.lastname: Tamura
authors.forename: Manabu
authors.initials: M
authors.lastname: Higaki
authors.forename: Saori
authors.initials: S
authors.lastname: Takata
authors.forename: Hiroo
authors.initials: H
authors.lastname: Wada
authors.forename: Haruyuki
authors.initials: H
authors.lastname: Ishii
authors.forename: Mitsuhiro
authors.initials: M
authors.lastname: Okazaki
authors.forename: Shinichi
authors.initials: S
authors.lastname: Takahashi
authors.forename: Hajime
authors.initials: H
authors.lastname: Goto
mesh_terms: D000368:Aged; D001426:Bacterial Proteins / Q000235:genetics; D006801:Humans; D007710:Klebsiella Infections; D007711:Klebsiella pneumoniae / Q000235:genetics; D008100:Liver Abscess / Q000209:etiology*; D008297:Male; D010641:Phenotype; D011655:Pulmonary Embolism / Q000209:etiology*; D014783:Viscosity
chemical_list: D001426:Bacterial Proteins; C512267:RmpA protein, Klebsiella pneumoniae