title: Laser trabeculoplasty for open-angle glaucoma: a report by the american academy of ophthalmology.
abstract: OBJECTIVE
  To provide an evidence-based summary of the outcomes, repeatability, and safety of laser trabeculoplasty for open-angle glaucoma.
  
  
  METHODS
  A search of the peer-reviewed literature in the PubMed and the Cochrane Library databases was conducted in June 2008 and was last repeated in March 2010 with no date or language restrictions. The search yielded 637 unique citations, of which 145 were considered to be of possible clinical relevance for further review and were included in the evidence analysis.
  
  
  RESULTS
  Level I evidence indicates an acceptable long-term efficacy of initial argon laser trabeculoplasty for open-angle glaucoma compared with initial medical treatment. Among the remaining studies, level II evidence supports the efficacy of selective laser trabeculoplasty for lowering intraocular pressure for patients with open-angle glaucoma. Level III evidence supports the efficacy of repeat use of laser trabeculoplasty.
  
  
  CONCLUSIONS
  Laser trabeculoplasty is successful in lowering intraocular pressure for patients with open-angle glaucoma. At this time, there is no literature establishing the superiority of any particular form of laser trabeculoplasty. The theories of action of laser trabeculoplasty are not elucidated fully. Further research into the differences among the lasers used in trabeculoplasty, the repeatability of the procedure, and techniques of treatment is necessary.
  
  
  BACKGROUND
  Proprietary or commercial disclosure may be found after the references.
authors.affiliation: Department of Ophthalmology, Oregon Health and Sciences University, Portland, Oregon, USA.
authors.forename: John R
authors.initials: JR
authors.lastname: Samples
authors.forename: Kuldev
authors.initials: K
authors.lastname: Singh
authors.forename: Shan C
authors.initials: SC
authors.lastname: Lin
authors.forename: Brian A
authors.initials: BA
authors.lastname: Francis
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Hodapp
authors.forename: Henry D
authors.initials: HD
authors.lastname: Jampel
authors.forename: Scott D
authors.initials: SD
authors.lastname: Smith
mesh_terms: D000047:Academies and Institutes; D016208:Databases, Factual; D005902:Glaucoma, Open-Angle / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology; D053685:Laser Therapy; D054018:Lasers, Excimer; D054023:Lasers, Semiconductor; D009885:Ophthalmology / Q000458:organization & administration / Q000592:standards*; D015203:Reproducibility of Results; D013673:Technology Assessment, Biomedical; D014129:Trabecular Meshwork / Q000601:surgery*; D014130:Trabeculectomy; D016896:Treatment Outcome; D014481:United States