title: [Heart involvement and pulmonary arterial hypertension in patients with systemic sclerosis].
abstract: In patients with systemic sclerosis heart involvement is often manifest, associated with poor prognosis and increased mortality. Cardiac involvement may be manifested by myocardial disease, arrhhythmias, conduction system disturbances, pericardial abnormalities and right heart failure, which develops as a complication of pulmonary arterial hypertension and significantly influences the disease progression. Pulmonary arterial hypertension is a severe and progressive disease with significant morbidity and mortality, being more often diagnosed. Diagnostic methods in evaluation of heart involvement as well as pulmonary arterial hypertension are presented. Today's treatment modalities are discussed.
authors.affiliation: Zavod za klinikku imunologiju i reumatologiju, Kispatićeva 12,10000 Zagreb.
authors.forename: Nada
authors.initials: N
authors.lastname: Cikes
mesh_terms: D006331:Heart Diseases / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D006976:Hypertension, Pulmonary / Q000150:complications* / Q000175:diagnosis; D012595:Scleroderma, Systemic / Q000150:complications* / Q000175:diagnosis