title: Calcium and vitamin d supplementation in men.
abstract: Calcium and vitamin D supplements reverse secondary hyperparathyroidism and are widely prescribed to prevent osteoporotic fractures, with proven antifracture efficacy when targeted to individuals with documented insufficiencies. Men who should particularly be considered for calcium and vitamin D supplements include elderly or institutionalized individuals, patients with documented osteoporosis on antiresorptive or anabolic medication, and individuals receiving glucocorticoids. Benefits are most apparent when a daily dose of 1000-1200 mg calcium is complemented with 800 IU vitamin D. Compliance is the key to optimizing clinical efficacy. While (conventionally dosed) vitamin D has not been associated with safety concerns, recent meta-analytic data have provided evidence to suggest that calcium supplements (without coadministered vitamin D) may potentially be associated with cardiovascular risks.
authors.affiliation: Division of Geriatric Medicine, Leuven University Hospital, Herestraat 49, 3000 Leuven, Belgium.
authors.forename: Evelien
authors.initials: E
authors.lastname: Gielen
authors.forename: Steven
authors.initials: S
authors.lastname: Boonen
authors.forename: Dirk
authors.initials: D
authors.lastname: Vanderschueren
authors.forename: Mieke
authors.initials: M
authors.lastname: Sinnesael
authors.forename: Annemieke
authors.initials: A
authors.lastname: Verstuyf
authors.forename: Frank
authors.initials: F
authors.lastname: Claessens
authors.forename: Koen
authors.initials: K
authors.lastname: Milisen
authors.forename: Sabine
authors.initials: S
authors.lastname: Verschueren