title: Coordination chemistry and biological activity of 5'-OH modified quinoline-B12 derivatives.
abstract: The consequences of structural modifications at the 5'-OH ribofuranotide moiety of quinoline modified B12 derivatives are discussed in regard of the coordination chemistry, the electrochemical properties and the biological behaviour of the compound.
authors.affiliation: Institute of Inorganic Chemistry, University of Zürich, Switzerland.
authors.forename: Karel
authors.initials: K
authors.lastname: Zelenka
authors.forename: Helmut
authors.initials: H
authors.lastname: Brandl
authors.forename: Bernhard
authors.initials: B
authors.lastname: Spingler
authors.forename: Felix
authors.initials: F
authors.lastname: Zelder
mesh_terms: D000900:Anti-Bacterial Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*; D049109:Cell Proliferation / Q000187:drug effects; D056831:Coordination Complexes / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*; D018360:Crystallography, X-Ray; D004305:Dose-Response Relationship, Drug; D004563:Electrochemistry; D048668:Lactobacillus delbrueckii / Q000166:cytology / Q000187:drug effects* / Q000254:growth & development; D008826:Microbial Sensitivity Tests; D008958:Models, Molecular; D015394:Molecular Structure; D011804:Quinolines / Q000737:chemistry*; D013237:Stereoisomerism; D013329:Structure-Activity Relationship; D013997:Time Factors; D014805:Vitamin B 12 / Q000737:chemistry / Q000494:pharmacology*
chemical_list: D000900:Anti-Bacterial Agents; D056831:Coordination Complexes; D011804:Quinolines; C037219:quinoline; D014805:Vitamin B 12