title: Life-threatening complications related to minocycline pleurodesis.
abstract: For decades, chemical pleurodesis using minocycline has been widely accepted as an effective, safe, and cheap treatment for persistent air leak after pulmonary resection. We report a case with persistent postoperative air leak that suffered from cardiorespiratory arrest just after a minocycline pleurodesis, which may be related to the aspiration of minocycline solution from a bronchopleural fistula. Therefore, we suggest a bronchoscopic examination be performed before the pleurodesis if a bronchopleural fistula is highly suspected.
authors.affiliation: Division of Thoracic Surgery, Department of Surgery, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.
authors.forename: Chia-Ying
authors.initials: CY
authors.lastname: Li
authors.forename: Shuenn-Wen
authors.initials: SW
authors.lastname: Kuo
authors.forename: Jang-Ming
authors.initials: JM
authors.lastname: Lee
mesh_terms: D000368:Aged; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000009:adverse effects; D001980:Bronchi / Q000601:surgery; D001983:Bronchial Fistula / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery; D001999:Bronchoscopy; D003937:Diagnosis, Differential; D005402:Fistula / Q000175:diagnosis / Q000209:etiology / Q000601:surgery; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008911:Minocycline / Q000008:administration & dosage / Q000009:adverse effects*; D010995:Pleural Diseases / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery; D018700:Pleurodesis / Q000009:adverse effects* / Q000379:methods; D011013:Pneumonectomy; D014057:Tomography, X-Ray Computed
chemical_list: D000900:Anti-Bacterial Agents; D008911:Minocycline