title: Increase of success rate for women undergoing embryo transfer by transcutaneous electrical acupoint stimulation: a prospective randomized placebo-controlled study.
abstract: OBJECTIVE
  To evaluate the effect of transcutaneous electrical acupoint stimulation (TEAS) on pregnancy rates (PR) in women undergoing ET.
  
  
  METHODS
  Prospective, randomized, single-blinded placebo-controlled clinical trial.
  
  
  METHODS
  Research and laboratory facilities.
  
  
  METHODS
  A total of 309 patients, less than 45 years old, undergoing cryopreservation embryos transplant or fresh cycle IVF with or without intracytoplasmic sperm injection (ICSI).
  
  
  METHODS
  The subjects were randomly allocated to three groups: mock TEAS treatment: 30 minutes after ET (group I, n = 99); single TEAS treatment: 30 minutes after ET (group II, n = 110); and double TEAS treatments: 24 hours before ET and 30 minutes after ET (group III, n = 100).
  
  
  METHODS
  Clinical PR, embryos implantation rate, live birth rate.
  
  
  RESULTS
  The clinical PR, embryos implantation rate, and live birth rate of group I (29.3%, 15.0%, and 21.2%, respectively) were significantly lower than those in group II (42.7%, 25.7%, and 37.3%, respectively) and group III (50.0%, 25.9%, and 42.0%, respectively).
  
  
  CONCLUSIONS
  Transcutaneous electrical acupoint stimulation, especially double TEAS, significantly improved the clinical outcome of ET.
authors.affiliation: Neuroscience Research Institute and Department of Neurobiology, Peking University Health Science Center, Key Laboratory of Neuroscience, The Ministry of Education and Ministry of Public Health, Beijing, People's Republic of China.
authors.forename: Rong
authors.initials: R
authors.lastname: Zhang
authors.forename: Xiao-Jun
authors.initials: XJ
authors.lastname: Feng
authors.forename: Qun
authors.initials: Q
authors.lastname: Guan
authors.forename: Wei
authors.initials: W
authors.lastname: Cui
authors.forename: Ying
authors.initials: Y
authors.lastname: Zheng
authors.forename: Wei
authors.initials: W
authors.lastname: Sun
authors.forename: Ji-Sheng
authors.initials: JS
authors.lastname: Han
mesh_terms: D015669:Acupuncture Points; D000328:Adult; D004624:Embryo Transfer / Q000295:instrumentation / Q000379:methods*; D005260:Female; D006801:Humans; D011247:Pregnancy; D018873:Pregnancy Rate / Q000639:trends*; D011446:Prospective Studies; D016037:Single-Blind Method; D004561:Transcutaneous Electric Nerve Stimulation / Q000295:instrumentation / Q000379:methods*; D016896:Treatment Outcome