title: Impact of a combined diet and progressive exercise intervention for overweight and obese children: the B.E. H.I.P. study.
abstract: The Biochemical Evaluation of a Health Intervention Programme (B.E. H.I.P.) investigated the impact of progressive exercise intensity in overweight and obese children. A 5-month prospective randomized crossover design (X(A), immediate intervention; O(B), control group; X(B), delayed intervention, O(A), postintervention follow-up) with a 10-week health intervention programme was employed. The intervention utilized a progressive increase in high-intensity exercise (≥ 75% maximum heart rate) and included 3 nutrition and 2 parent education sessions. Primary analysis was completed with (i) X(A) versus O(B) and (ii) all intervention participants (collapsed X(A) and X(B) = X(A)X(B)). Prepubertal overweight and obese male and female children (n = 27) between 5 and 10 years of age were randomly allocated to X(A) (n = 16; 11 females; waist circumference = 80.0 ± 10.6 cm) or O(B) (n = 11; 3 females; waist circumference = 76.6 ± 7.5 cm). The primary variables were heart rate and percent fat mass. All variables, including body composition, habitual activity, and serum lipids, were repeatedly measured for up to a maximum of 7 time points. Energy expenditure was quantitatively measured throughout each exercise class (n = 20). A significantly longer time in the exercise sessions was spent in high-intensity (35.1%-60.0%) versus low- to moderate-intensity (64.9%-40.0%) exercise as the intervention progressed from the first to the last attended exercise class (Fisher exact test, p < 0.0001). The percent fat mass decreased in all intervention participants (-2.2%, p < 0.0001). X(A) had a greater slope decrease than O(B) for percent fat mass (p = 0.00051) and triglycerides (p = 0.0467). In conclusion, high-intensity exercise, within a comprehensive health programme that includes nutrition education, improved the lipid and physiological health profiles of obese children.
authors.affiliation: Faculty of Kinesiology, University of Calgary, Calgary, AB T2N 1N4, Canada. pdoyleba@ucalgary.ca
authors.forename: Patricia K
authors.initials: PK
authors.lastname: Doyle-Baker
authors.forename: Allison A
authors.initials: AA
authors.lastname: Venner
authors.forename: Martha E
authors.initials: ME
authors.lastname: Lyon
authors.forename: Tak
authors.initials: T
authors.lastname: Fung
mesh_terms: D000273:Adipose Tissue / Q000378:metabolism; D001794:Blood Pressure / Q000502:physiology; D015992:Body Mass Index; D002648:Child; D002675:Child, Preschool; D018592:Cross-Over Studies; D004038:Diet, Reducing / Q000379:methods*; D002149:Energy Intake / Q000502:physiology; D004734:Energy Metabolism / Q000502:physiology; D015444:Exercise / Q000502:physiology*; D005260:Female; D005500:Follow-Up Studies; D015438:Health Behavior; D006266:Health Education / Q000379:methods*; D006293:Health Promotion / Q000379:methods*; D006339:Heart Rate / Q000502:physiology; D006801:Humans; D008055:Lipids / Q000097:blood; D008297:Male; D009752:Nutritional Status; D009765:Obesity / Q000097:blood / Q000628:therapy; D050177:Overweight / Q000097:blood / Q000628:therapy*; D011446:Prospective Studies; D013997:Time Factors; D016896:Treatment Outcome; D015431:Weight Loss / Q000502:physiology
chemical_list: D008055:Lipids