title: In vitro human skin segmentation and drug concentration-skin depth profiles.
abstract: Highly optimized methods for skin segmentation are provided using tape stripping in combination with infrared absorption measurements for stratum corneum (SC) and cryosectioning for deeper skin layers. Furthermore, an example is calculated for demonstration of the respective procedures.
authors.affiliation: Biopharmaceutics and Pharmaceutical Technology, Saarland University, Saarbrucken, Germany.
authors.forename: Ana
authors.initials: A
authors.lastname: Melero
authors.forename: Tsambika
authors.initials: T
authors.lastname: Hahn
authors.forename: Ulrich F
authors.initials: UF
authors.lastname: Schaefer
authors.forename: Marc
authors.initials: M
authors.lastname: Schneider
mesh_terms: D001706:Biopsy; D002245:Carbon Dioxide / Q000737:chemistry; D016616:Cryoultramicrotomy; D003720:Densitometry; D004058:Diffusion; D004817:Epidermis / Q000378:metabolism / Q000648:ultrastructure; D006801:Humans; D007259:Infrared Rays; D007700:Kinetics; D008867:Microtomy / Q000379:methods*; D009929:Organ Size; D012869:Skin Absorption; D053832:Surgical Tape
chemical_list: D002245:Carbon Dioxide