title: Stereoselective 6-exo cyclization of amidyl radicals. An experimental and theoretical study.
abstract: Unsaturated primary amidyl radicals of Z-configurations underwent efficient chemo- and stereoselective 6-exo cyclization reactions via chair-conformational transition states, leading to the predominant formations of 3,6-trans, 4,6-cis, or 5,6-trans substituted δ-lactams.
authors.affiliation: Key Laboratory of Synthetic Chemistry of Natural Substances, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, PR China.
authors.forename: Shunjun
authors.initials: S
authors.lastname: Zhuang
authors.forename: Kun
authors.initials: K
authors.lastname: Liu
authors.forename: Chaozhong
authors.initials: C
authors.lastname: Li
mesh_terms: D000577:Amides / Q000737:chemistry*; D003500:Cyclization; D008958:Models, Molecular; D008968:Molecular Conformation; D011789:Quantum Theory; D013237:Stereoisomerism; D013379:Substrate Specificity; D013816:Thermodynamics
chemical_list: D000577:Amides