title: Cross-resistance patterns and fitness in fufenozide-resistant diamondback moth, Plutella xylostella (Lepidoptera: Plutellidae).
abstract: BACKGROUND
  Fufenozide is a novel non-steroidal ecdysone agonist with good efficacy against diamondback moth (DBM), Plutella xylostella (Lepidoptera: Plutellidae). At present, it is widely applied for the control of a range of lepidopterous pests in China. This study compared the activities of fufenozide and 12 other insecticides against unselected and fufenozide-selected strains of DBM to examine potential patterns of cross-resistance. The relative fitness of the fufenozide-selected strain was assessed to provide information pertinent to insecticide resistance management.
  
  
  RESULTS
  Compared with the susceptible strain (JSS), the fufenozide-resistant strain (JSR) showed high cross-resistance to dibenzoylhydrazines and benzoylphenylureas, low cross-resistance to abamectin and no cross-resistance to organophosphates, carbamates and pyrethroids. JSR had a lower reproductive ability and a relative fitness of 0.5 compared with JSS.
  
  
  CONCLUSIONS
  P. xylostella has the potential to develop resistance to fufenozide, albeit at the expense of fitness. Cross-resistance between the same and other classes of insecticides is of concern, and should be a key consideration when implementing fufenozide-based control strategies for this species.
authors.affiliation: Department of Entomology, China Agricultural University, Beijing 100193, China.
authors.forename: Jingyan
authors.initials: J
authors.lastname: Sun
authors.forename: Pei
authors.initials: P
authors.lastname: Liang
authors.forename: Xiwu
authors.initials: X
authors.lastname: Gao
mesh_terms: D000818:Animals; D001572:Benzofurans; D005260:Female; D006834:Hydrazines; D007305:Insecticide Resistance; D007306:Insecticides; D008018:Life Cycle Stages; D008297:Male; D009036:Moths / Q000254:growth & development
chemical_list: D001572:Benzofurans; D006834:Hydrazines; D007306:Insecticides; C550384:fufenozide