title: Off-pump coronary artery bypass grafting in elderly and high-risk patients--a review.
abstract: Elderly and high-risk patients are increasingly being considered for myocardial revascularisation. Most trials comparing the various options for revascularisation exclude elderly and 'high-risk' patients. We have reviewed the options for myocardial revascularisation for elderly patients, and for patients with a number of common 'high-risk' co-morbidities--diabetes mellitus, renal insufficiency, poor left ventricular ejection fraction, peripheral vascular disease, left main coronary artery disease and chronic obstructive pulmonary disease--with a focus on coronary artery bypass grafting without the use of cardiopulmonary bypass and aortic manipulation.
authors.affiliation: Cardiothoracic Surgical Unit, RPA Medical Center, Royal Prince Alfred Hospital, 304/100 Carillon Ave, Newtown, Sydney, NSW 2042, Australia.
authors.forename: Edward A
authors.initials: EA
authors.lastname: Cooper
authors.forename: J James B
authors.initials: JJ
authors.lastname: Edelman
authors.forename: Michael K
authors.initials: MK
authors.lastname: Wilson
authors.forename: Paul G
authors.initials: PG
authors.lastname: Bannon
authors.forename: Michael P
authors.initials: MP
authors.lastname: Vallely
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002986:Clinical Trials as Topic; D047549:Coronary Artery Bypass, Off-Pump / Q000379:methods*; D003324:Coronary Artery Disease / Q000150:complications / Q000601:surgery; D003920:Diabetes Mellitus / Q000601:surgery; D005260:Female; D006299:Health Services for the Aged; D006801:Humans; D008297:Male; D016491:Peripheral Vascular Diseases / Q000150:complications / Q000601:surgery; D029424:Pulmonary Disease, Chronic Obstructive / Q000150:complications / Q000601:surgery; D051437:Renal Insufficiency / Q000150:complications / Q000601:surgery; D012307:Risk Factors; D013318:Stroke Volume