title: Physical activity (PA) and the disablement process: a 14-year follow-up study of older non-disabled women and men.
abstract: Few studies have explored the associations of reported PA (RPA) with the processes underlying the development of disability. The present study was performed to explore RPA among older persons and its association with onset of functional dependence and mortality. Among a probability sample of 1782 community-living persons, aged 75-83 years, we evaluated the 1021 who reported no disability in basic activities of daily living. Participants were followed for a median of 8.34 years in public registers to determine onset of disability and mortality. RPA predicted mortality in older women (HR=1.77, 95%CI=1.42-2.19) and men (HR=1.65, 95%CI=1.27-2.14) over long time intervals. The effect of RPA persisted among permanently disabled older women, after adjusting for age, baseline vulnerability and grade of disability. Low RPA was independently associated with risk of incident disability (HR=1.56, 95%CI=1.10-2.23) in men. Among older women, the association between RPA and incidence of disability was attenuated in analyses that controlled for baseline mobility function. Thus, the association between physical activity and mortality reflected processes different from those underlying a simple relation between physical activity, disability and mortality. Physical activity was an ubiquitous predictor of longevity, but only for women.
authors.affiliation: Department of Occupational and Environmental Medicine, Copenhagen University Hospital, Bispebjerg, Bispebjerg Bakke 23, Copenhagen, DK 2200 NV, Denmark. ejj@post5.tele.dk
authors.forename: Kirsten
authors.initials: K
authors.lastname: Schultz-Larsen
authors.forename: Naghmeh
authors.initials: N
authors.lastname: Rahmanfard
authors.forename: Claus
authors.initials: C
authors.lastname: Holst
mesh_terms: D000203:Activities of Daily Living; D017668:Age of Onset; D000368:Aged; D000369:Aged, 80 and over; D002423:Cause of Death; D006233:Persons with Disabilities / Q000706:statistics & numerical data*; D005260:Female; D005500:Follow-Up Studies; D015577:Geriatric Assessment / Q000706:statistics & numerical data*; D006801:Humans; D015994:Incidence; D008136:Longevity; D008297:Male; D009043:Motor Activity; D012111:Residence Characteristics / Q000706:statistics & numerical data; D012306:Risk; D012720:Severity of Illness Index; D012737:Sex Factors