title: Management of vaginal agenesis.
abstract: Rokitansky syndrome and complete androgen insensitivity syndrome are the most common causes of vaginal agenesis. Treatment should be deferred until adolescence to allow informed consent and compliance. The best treatment for vaginal agenesis remains controversial although vaginal dilation therapy is still widely considered the first line treatment because success rates are high and associated risks are low. A variety of surgical options are also available, each with enthusiastic proponents. Long-term outcome studies on most surgical techniques, however, are still lacking and until recently most studies have reported on success rate in terms of anatomical success only, without including sexual function. Moreover, the medical literature lacks prospective comparative outcome studies, meaning that current choice of surgical procedure relies greatly on the surgeon's preference and experience.
authors.affiliation: UCL Institute of Women's Health, University College London Hospitals, London, UK. rolanakhal@homail.com
authors.forename: Rola S
authors.initials: RS
authors.lastname: Nakhal
authors.forename: Sarah M
authors.initials: SM
authors.lastname: Creighton
mesh_terms: D058489:46, XX Disorders of Sex Development; D000015:Abnormalities, Multiple / Q000601:surgery* / Q000628:therapy; D013734:Androgen-Insensitivity Syndrome / Q000601:surgery* / Q000628:therapy; D000013:Congenital Abnormalities; D004106:Dilatation; D005260:Female; D006801:Humans; D007668:Kidney / Q000002:abnormalities / Q000601:surgery; D008297:Male; D009095:Mullerian Ducts / Q000002:abnormalities / Q000601:surgery; D019170:Somites / Q000002:abnormalities / Q000601:surgery; D013131:Spine / Q000002:abnormalities / Q000601:surgery; D013997:Time Factors; D014599:Uterus / Q000002:abnormalities / Q000601:surgery; D014621:Vagina / Q000002:abnormalities* / Q000601:surgery