title: Extraction and isolation of shikimic acid from Ginkgo biloba leaves utilizing an ionic liquid that dissolves cellulose.
abstract: Shikimic acid, the starting material in the commercial synthesis of oseltamivir phosphate (Tamiflu®), was efficiently extracted and isolated from Ginkgo biloba leaves utilizing the ionic liquid 1-butyl-3-methylimidazolium chloride ([bmim]Cl), which dissolves cellulose.
authors.affiliation: Department of Materials and Life Sciences, Faculty of Science and Technology, Sophia University, Tokyo 102-8554, Japan. t-usuki@sophia.ac.jp
authors.forename: Toyonobu
authors.initials: T
authors.lastname: Usuki
authors.forename: Nanae
authors.initials: N
authors.lastname: Yasuda
authors.forename: Masahiro
authors.initials: M
authors.lastname: Yoshizawa-Fujita
authors.forename: Masahiro
authors.initials: M
authors.lastname: Rikukawa
mesh_terms: D002482:Cellulose / Q000737:chemistry*; D002851:Chromatography, High Pressure Liquid; D056148:Chromatography, Reverse-Phase; D020441:Ginkgo biloba / Q000737:chemistry*; D007093:Imidazoles / Q000737:chemistry; D052578:Ionic Liquids / Q000737:chemistry*; D018515:Plant Leaves / Q000737:chemistry; D012765:Shikimic Acid / Q000737:chemistry* / Q000302:isolation & purification
chemical_list: D007093:Imidazoles; D052578:Ionic Liquids; D012765:Shikimic Acid; C502841:1-butyl-3-methylimidazolium chloride; D002482:Cellulose