title: AtAGP18, a lysine-rich arabinogalactan protein in Arabidopsis thaliana, functions in plant growth and development as a putative co-receptor for signal transduction.
abstract: Arabinogalactan-proteins (AGPs) are a class of hyperglycosylated, hydroxyproline-rich glycoproteins that are widely distributed in the plant kingdom. AtAGP17, 18 and 19 are homologous genes encoding three classical lysine-rich AGPs in Arabidopsis. We observed subcellular localization of AtAGP18 at the plasma membrane by expressing a translational fusion gene construction of AtAGP18 attached to a green fluorescent protein (GFP) tag in Arabidopsis plants. We also overexpressed AtAGP18 without the GFP tag in Arabidopsis plants, and the resulting transgenic plants had a short, bushy phenotype. Here we discuss putative roles of AtAGP18 as a glycosylphosphatidylinositol (GPI)-anchored protein involved in a signal transduction pathway regulating plant growth and development.
authors.affiliation: Department of Environmental and Plant Biology, Molecular and Cellular Biology Program, Ohio University, Athens, Ohio, USA.
authors.forename: Yizhu
authors.initials: Y
authors.lastname: Zhang
authors.forename: Jie
authors.initials: J
authors.lastname: Yang
authors.forename: Allan M
authors.initials: AM
authors.lastname: Showalter
mesh_terms: D017360:Arabidopsis / Q000254:growth & development* / Q000378:metabolism*; D029681:Arabidopsis Proteins / Q000378:metabolism*; D008239:Lysine / Q000378:metabolism*; D008562:Membrane Glycoproteins / Q000378:metabolism*; D008954:Models, Biological; D009088:Mucoproteins / Q000378:metabolism*; D010940:Plant Proteins / Q000378:metabolism; D015398:Signal Transduction
chemical_list: C559462:AGP18 protein, Arabidopsis; D029681:Arabidopsis Proteins; D008562:Membrane Glycoproteins; D009088:Mucoproteins; D010940:Plant Proteins; C006619:arabinogalactan proteins; D008239:Lysine