title: Sperm storage for cancer patients in the UK: a review of current practice.
abstract: An increasing number of cancer patients can now hope to have a full and normal life due to significant improvements in treatment outcomes and survival rates. The application of cryobiology to store fertile gametes before sterilizing treatments has been a natural progression. Greater awareness has markedly increased the worldwide demand for long-term storage of sperm, and has prompted the UK Human Fertilization and Embryology Authority to extend the period of storage permitted by their regulations to 55 years. Other patients undergoing sterilizing chemotherapy and/or radiotherapy such as haemoglobinopathies requiring bone marrow transplantation and autoimmune disorders such as rheumatoid arthritis may further increase the indications for sperm storage. Most adult and adolescent patients and their relatives/spouses/parents/guardians value this service even though very few eventually use the sperm. There is an urgent need to develop national and international guidelines for the provision, organization, maintenance and management of the cryopreservation services.
authors.affiliation: The Leeds Centre for Reproductive Medicine, Seacroft Hospital, Leeds LS146UH, UK. vinay.sharma@leedsth.nhs.uk
authors.forename: Vinay
authors.initials: V
authors.lastname: Sharma
mesh_terms: D000293:Adolescent; D000328:Adult; D000970:Antineoplastic Agents / Q000009:adverse effects; D015925:Cryopreservation / Q000379:methods; D005260:Female; D005615:Freezing; D006801:Humans; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000150:complications / Q000473:pathology / Q000628:therapy*; D012662:Semen Preservation / Q000379:methods* / Q000592:standards; D013094:Spermatozoa / Q000166:cytology* / Q000473:pathology; D011795:Surveys and Questionnaires; D006113:United Kingdom
chemical_list: D000970:Antineoplastic Agents