title: Diastereo- and enantioselective conjugate addition of α-substituted nitroacetates to maleimides under base-free neutral phase-transfer conditions.
abstract: Highly diastereo- and enantioselective conjugate addition of α-substituted nitroacetates to maleimides under base-free neutral phase-transfer conditions was developed for the synthesis of α,α-disubstituted α-amino acid derivatives.
authors.affiliation: Laboratory of Synthetic Organic Chemistry, Department of Chemistry, Graduate School of Science, Kyoto University, Sakyo, Kyoto, 606-8502, Japan.
authors.forename: Seiji
authors.initials: S
authors.lastname: Shirakawa
authors.forename: Shogo J
authors.initials: SJ
authors.lastname: Terao
authors.forename: Rongjun
authors.initials: R
authors.lastname: He
authors.forename: Keiji
authors.initials: K
authors.lastname: Maruoka
mesh_terms: D000085:Acetates / Q000737:chemistry*; D002384:Catalysis; D018360:Crystallography, X-Ray; D008301:Maleimides / Q000138:chemical synthesis / Q000737:chemistry*; D008968:Molecular Conformation; D013237:Stereoisomerism
chemical_list: D000085:Acetates; D008301:Maleimides; C028257:nitroacetic acid