title: Differential diagnosis of acute abdominal pain - acute intermittent porphyria.
abstract: Acute intermittent porphyria (AIP) is a rare autosomal dominant disorder of heme biosynthesis in liver due to deficiency of porphobilinogen deaminase enzyme. Clinically, AIP is dominated by a colicky type pain, which does not subside after taking usual analgesics. Additional frequent symptoms are vomiting, hypertension, peripheral neuropathy, seizures, depression, delirium and coma. This paper reported a case of a twenty-five- year-old female patient, who had undergone a period of six days between the first presentation to the medical department and the diagnosis confirmation. It has accentuated possible mistakes in symptomatic therapy administration as well as dangers of a delayed diagnosis.
authors.affiliation: Department of Internal Medicine, General Hospital Bjelovar, Croatia. mislav.klobucic@bj.t-com.hr
authors.forename: Mislav
authors.initials: M
authors.lastname: Klobucić
authors.forename: Duska
authors.initials: D
authors.lastname: Sklebar
authors.forename: Renata
authors.initials: R
authors.lastname: Ivanac
authors.forename: Dragica
authors.initials: D
authors.lastname: Vrabec Matković
authors.forename: Anita
authors.initials: A
authors.lastname: Jug-Klobucić
authors.forename: Ivan
authors.initials: I
authors.lastname: Sklebar
mesh_terms: D000006:Abdomen, Acute / Q000209:etiology*; D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D017118:Porphyria, Acute Intermittent / Q000150:complications / Q000175:diagnosis*