title: Quantification of Clostridium difficile in antibiotic-associated-diarrhea patients.
abstract: Comparing culture- and non-culture-based methods for quantifying Clostridium difficile in antibiotic-associated-diarrhea patients, we found that the real-time PCR method correlated well with quantitative culture and was more sensitive. A positive association between the population levels of C. difficile and the presence of its toxins was found.
authors.affiliation: Department of Medical Microbiology, Stavanger University Hospital, Postbox 8100, 4068 Stavanger, Norway. napa@sus.no
authors.forename: Paul
authors.initials: P
authors.lastname: Naaber
authors.forename: Jelena
authors.initials: J
authors.lastname: Stsepetova
authors.forename: Imbi
authors.initials: I
authors.lastname: Smidt
authors.forename: Merle
authors.initials: M
authors.lastname: Rätsep
authors.forename: Siiri
authors.initials: S
authors.lastname: Kõljalg
authors.forename: Krista
authors.initials: K
authors.lastname: Lõivukene
authors.forename: Liis
authors.initials: L
authors.lastname: Jaanimäe
authors.forename: Iren H
authors.initials: IH
authors.lastname: Löhr
authors.forename: Olav B
authors.initials: OB
authors.lastname: Natås
authors.forename: Kai
authors.initials: K
authors.lastname: Truusalu
authors.forename: Epp
authors.initials: E
authors.lastname: Sepp
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D058491:Bacterial Load / Q000379:methods*; D001427:Bacterial Toxins / Q000032:analysis; D002648:Child; D002675:Child, Preschool; D016360:Clostridioides difficile / Q000302:isolation & purification*; D003015:Clostridium Infections / Q000382:microbiology*; D003967:Diarrhea / Q000382:microbiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012680:Sensitivity and Specificity; D013223:Statistics as Topic; D055815:Young Adult
chemical_list: D000900:Anti-Bacterial Agents; D001427:Bacterial Toxins