title: Amblyopia and strabismus by monocular corneal opacity following suspected epidemic keratoconjunctivitis in infancy.
abstract: OBJECTIVE
  To identify the long term clinical course of amblyopia and strabismus that developed secondary to a monocular corneal opacity following suspected epidemic keratoconjunctivitis (EKC) in infancy.
  
  
  METHODS
  This was a retrospective study analyzing the medical records of seven patients, treated in our clinic, who were followed for more than five years.
  
  
  RESULTS
  Four patients in our clinic underwent a corneal ulcer treatment following suspected EKC. Each developed a monocular corneal opacity. Three patients with a chief complaint of corneal opacity were transferred to our clinic from other clinics. These patients had documented histories of treatment for EKC in infancy. All patients were treated with early occlusion therapy, but amblyopia persisted in four patients. Furthermore, all patients had strabismus and showed a significant reduction of stereoscopic vision.
  
  
  CONCLUSIONS
  Although infants with EKC are not always cooperative, slit lamp examination should be performed as early as possible, and appropriate medical treatment should be performed, thus reducing the development of corneal opacity. Careful follow up should be regularly performed, and the occurrence of amblyopia or strabismus should be verified at an early stage using visual acuity or ocular alignment examination. Ophthalmologic treatments, including active occlusion therapy, should also be pursued.
authors.affiliation: Department of Ophthalmology, Yeungnam University College of Medicine, #317-1 Daemyeong-dong, Nam-gu, Daegu, Korea.
authors.forename: Byoungyoung
authors.initials: B
authors.lastname: Gu
authors.forename: Junhyuk
authors.initials: J
authors.lastname: Son
authors.forename: Myungmi
authors.initials: M
authors.lastname: Kim
mesh_terms: D000257:Adenoviridae Infections / Q000150:complications* / Q000175:diagnosis / Q000453:epidemiology; D000550:Amblyopia / Q000209:etiology* / Q000473:pathology / Q000503:physiopathology; D002648:Child; D002675:Child, Preschool; D003318:Corneal Opacity / Q000150:complications* / Q000473:pathology; D018450:Disease Progression; D058872:Epidemics; D015828:Eye Infections, Viral / Q000150:complications* / Q000175:diagnosis / Q000453:epidemiology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007637:Keratoconjunctivitis / Q000150:complications* / Q000175:diagnosis / Q000453:epidemiology; D008297:Male; D011379:Prognosis; D012029:Refraction, Ocular; D056910:Republic of Korea / Q000453:epidemiology; D012189:Retrospective Studies; D012307:Risk Factors; D013285:Strabismus / Q000209:etiology* / Q000473:pathology / Q000503:physiopathology; D015348:Vision, Binocular; D014792:Visual Acuity