title: [Neuroendocrine factors in hypertension during pregnancy].
abstract: Pregnancy induced hypertension is a condition of high blood pressure during early and mid-pregnancy. This type of hypertension is much like the chronic type, but it occurs only when the woman is pregnant and resolves completely after delivery.
  
  
  OBJECTIVE
  to evaluate some stress hormones in both normotensive and hypertensive pregnant women.
  
  
  METHODS
  The study investigated the correlation between pregnancy induced hypertension and different immune/inflammatory and other markers. This exploratory investigation was performed on pregnant women diagnosed with pregnancy-induced hypertension, admitted to the lasi Cuza Voda Hospital. The psychometric assessment was performed by using the daily stress test, daily hassle scale, blood pressure measurements, and determination of anthropometrical parameters. Some parameters, such as the neuroendocrine and immune/inflammatory ones, and specific parameters for pregnancy hypertension were determined.
  
  
  CONCLUSIONS
  Our study revealed that blood pressure values presented significant differences between systolic, but not diastolic blood pressure values (p < 0.05). In 75% of subjects blood cortisol levels were not changed. Daily stress level assessment proved that low potential factors and an annoying environment had a high influence on both normotensive and hypertensive pregnant women. Hypertensive women also presented leukocytosis and thrombocytopenia.
  
  
  CONCLUSIONS
  The research results showed that plasma cortisol level was higher in hypertensive pregnant women, compared with normotensives.
authors.affiliation: Universităţii de Medicină şi Farmacie Gr. T. Popa Iaşi, Universitatea de Medicină şi Farmacie Gr. T. Popa Iaşi, Facultatea de Medicină, Disciplina de Farmacologie.
authors.forename: Minodora
authors.initials: M
authors.lastname: Diaconu
authors.forename: Cristina-Mihaela
authors.initials: CM
authors.lastname: Ghiciuc
authors.forename: Liliana
authors.initials: L
authors.lastname: Tarţău
authors.forename: Cătălina-Elena
authors.initials: CE
authors.lastname: Lupuşoru
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000097:blood; D001794:Blood Pressure; D001795:Blood Pressure Determination; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000097:blood*; D006973:Hypertension / Q000097:blood* / Q000503:physiopathology; D007964:Leukocytosis / Q000097:blood; D008019:Life Style; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000097:blood* / Q000503:physiopathology; D011594:Psychometrics; D012307:Risk Factors; D013315:Stress, Psychological / Q000097:blood / Q000503:physiopathology; D013921:Thrombocytopenia / Q000097:blood
chemical_list: D015415:Biomarkers; D006854:Hydrocortisone