title: Some more fundamental problems in clinical research: comment on "Statistical significance testing and clinical trials".
abstract: Comments on an article "Statistical significance testing and clinical trials" by Merton S. Krause (see record 2011-19228-002). The article provides a thought-provoking and critical discussion of the conventional statistical testing in clinical research. Krause argues that, by focusing exclusively on mean differences between groups and their statistical significance, important information about the individual participant is being ignored. This article argues a few central issues with Krause's article.
authors.affiliation: Department of Psychology, Boston University, Boston, MA 02215, USA. shofmann@bu.edu
authors.forename: Stefan G
authors.initials: SG
authors.lastname: Hofmann
mesh_terms: D006801:Humans; D017063:Outcome Assessment, Health Care / Q000379:methods*; D011613:Psychotherapy / Q000379:methods*; D016032:Randomized Controlled Trials as Topic / Q000706:statistics & numerical data*; D012107:Research Design / Q000706:statistics & numerical data*