title: An experimental study on the application of radionuclide imaging in repair of the bone defect.
abstract: The aim of our study was to validate the effect of radionuclide imaging in early monitoring of the bone's reconstruction, the animal model of bone defect was made on the rabbits repaired with HA artificial bone. The ability of bone defect repair was evaluated by using radionuclide bone imaging at 2, 4, 8 and 12 weeks postoperatively. The results indicate that the experimental group stimulated more bone formation than that of the control group. The differences of the bone reconstruction ability were statistically significant (p<0.05). The nano-HA artificial has good bone conduction, and it can be used for the treatment of bone defects. Radionuclide imaging may be an effective and first choice method for the early monitoring of the bone's reconstruction.
authors.affiliation: Department of Sports Medicine, Shenzhen Second People's Hospital, Futian district, P.R. China.
authors.forename: Weimin
authors.initials: W
authors.lastname: Zhu
authors.forename: Daping
authors.initials: D
authors.lastname: Wang
authors.forename: Xiaojun
authors.initials: X
authors.lastname: Zhang
authors.forename: Wei
authors.initials: W
authors.lastname: Lu
authors.forename: Jianquan
authors.initials: J
authors.lastname: Liu
authors.forename: Liangquan
authors.initials: L
authors.lastname: Peng
authors.forename: Hao
authors.initials: H
authors.lastname: Li
authors.forename: Yun
authors.initials: Y
authors.lastname: Han
authors.forename: Yanjun
authors.initials: Y
authors.lastname: Zeng
mesh_terms: D000818:Animals; D001861:Bone Regeneration / Q000502:physiology*; D018786:Bone Substitutes; D001842:Bone and Bones / Q000098:blood supply / Q000000981:diagnostic imaging* / Q000293:injuries / Q000601:surgery; D017886:Durapatite; D008297:Male; D049329:Nanostructures; D011817:Rabbits; D019275:Radiopharmaceuticals; D012039:Regional Blood Flow; D013669:Technetium Tc 99m Medronate; D015899:Tomography, Emission-Computed, Single-Photon
chemical_list: D018786:Bone Substitutes; D019275:Radiopharmaceuticals; D017886:Durapatite; D013669:Technetium Tc 99m Medronate