title: Determination of dicofol in aquatic products using molecularly imprinted solid-phase extraction coupled with GC-ECD detection.
abstract: The novel molecularly imprinted microsphere (MIM) that could be applied as special sorbent was synthesized by aqueous suspension polymerization using 1,1-bis(4-chlorophenyl)-1,2,2,2-tetrachloroethane (α-chloro-DDT) as the dummy template. The obtained MIM exhibited good recognition and selectivity to dicofol and it was successfully applied as selective sorbent of solid-phase extraction for the determination of dicofol from aquatic products. At the optimum conditions of the molecularly imprinted solid-phase extraction (MISPE) coupled with GC-ECD, good linearity for dicofol was achieved in a range of 0.4-100 ng g(-1) (r(2)=0.9995) and the recoveries at three spiked levels were ranged from 85.8% to 101.2% for aquatic products with the relative standard deviation (RSD) less than 5.6%. The presented MISPE-GC-ECD method exhibited the advantages of simplicity, selectivity and sensitivity, and could be potentially applied to the determination of dicofol in complicated aquatic products.
authors.affiliation: Key Laboratory of Pharmaceutical Quality Control of Hebei Province & College of Pharmacy, Hebei University, Baoding 071002, China.
authors.forename: Hui
authors.initials: H
authors.lastname: Wang
authors.forename: Hongyuan
authors.initials: H
authors.lastname: Yan
authors.forename: Mande
authors.initials: M
authors.lastname: Qiu
authors.forename: Jindong
authors.initials: J
authors.lastname: Qiao
authors.forename: Gengliang
authors.initials: G
authors.lastname: Yang
mesh_terms: D000818:Animals; D059001:Aquatic Organisms / Q000737:chemistry*; D002849:Chromatography, Gas / Q000379:methods*; D003634:DDT / Q000031:analogs & derivatives / Q000737:chemistry; D033364:Decapoda / Q000737:chemistry; D004010:Dicofol / Q000032:analysis* / Q000302:isolation & purification*; D004583:Electrons; D004785:Environmental Pollutants / Q000032:analysis / Q000302:isolation & purification; D005399:Fishes; D008863:Microspheres; D054802:Molecular Imprinting / Q000379:methods*; D052616:Solid Phase Extraction / Q000379:methods*
chemical_list: D004785:Environmental Pollutants; C051165:alpha-chloro-DDT; D003634:DDT; D004010:Dicofol