title: Intramedullary cavernous angiomas of the spinal cord: clinical characteristics of 13 lesions.
abstract: Magnetic resonance imaging has increased the incidence of the diagnosis of intramedullary cavernous angioma. Surgical therapy tends not to be recommended for asymptomatic lesions, but symptomatic lesions that bleed recurrently should be treated. The natural course of intramedullary cavernous angioma remains unknown and arguments have been raised against the surgical treatment of symptomatic lesions. We reviewed the clinical features of 13 intramedullary cavernous angiomas in 12 patients surgically treated between 1988 and 2009. The 7 men and 5 women were aged from 14 to 60 years, the preoperative interval ranged from 0 to 161 months, and the mean number of hemorrhages in the 13 lesions was 2.5. Sixteen operations were performed to treat the 13 lesions. The surgical approach depended on the lesion location. The outcome of patients with mild to moderate preoperative symptoms (McCormick grades I-III) was significantly better than that of patients with severe symptoms (McCormick grade IV) (p < 0.05). Symptomatic intramedullary cavernous angioma tends to bleed repeatedly. The lesion should be surgically removed to avoid further deterioration due to recurrent hemorrhages. The shortest path approach should be selected based on preoperative images and complete removal should be attempted. Residual lesion may be masked by surrounding gliosis, so careful postoperative follow up is necessary.
authors.affiliation: Department of Neurosurgery, Hokkaido University Graduate School of Medicine, Sapporo, Hokkaido, Japan. taoya@sirius.ocn.ne.jp
authors.forename: Takeshi
authors.initials: T
authors.lastname: Aoyama
authors.forename: Kazutoshi
authors.initials: K
authors.lastname: Hida
authors.forename: Kiyohiro
authors.initials: K
authors.lastname: Houkin
mesh_terms: D000293:Adolescent; D000328:Adult; D015897:Comorbidity / Q000639:trends; D003937:Diagnosis, Differential; D005260:Female; D020786:Hemangioma, Cavernous, Central Nervous System / Q000175:diagnosis / Q000453:epidemiology / Q000601:surgery*; D006470:Hemorrhage / Q000175:diagnosis / Q000453:epidemiology / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D019635:Neurosurgical Procedures / Q000379:methods* / Q000592:standards; D012189:Retrospective Studies; D013120:Spinal Cord Neoplasms / Q000175:diagnosis / Q000453:epidemiology / Q000601:surgery*; D014656:Vascular Surgical Procedures / Q000379:methods* / Q000592:standards; D055815:Young Adult