title: Biofunctionalization of zinc oxide nanowires for DNA sensory applications.
abstract: We report on the biofunctionalization of zinc oxide nanowires for the attachment of DNA target molecules on the nanowire surface. With the organosilane glycidyloxypropyltrimethoxysilane acting as a bifunctional linker, amino-modified capture molecule oligonucleotides have been immobilized on the nanowire surface. The dye-marked DNA molecules were detected via fluorescence microscopy, and our results reveal a successful attachment of DNA capture molecules onto the nanowire surface. The electrical field effect induced by the negatively charged attached DNA molecules should be able to control the electrical properties of the nanowires and gives way to a ZnO nanowire-based biosensing device.
authors.affiliation: Institute of Solid State Physics, Friedrich-Schiller-Universität, Max-Wien-Platz 1, 07743 Jena, Germany. raphael.niepelt@uni-jena.de.
authors.forename: Raphael
authors.initials: R
authors.lastname: Niepelt
authors.forename: Ulrich C
authors.initials: UC
authors.lastname: Schröder
authors.forename: Jana
authors.initials: J
authors.lastname: Sommerfeld
authors.forename: Irma
authors.initials: I
authors.lastname: Slowik
authors.forename: Bettina
authors.initials: B
authors.lastname: Rudolph
authors.forename: Robert
authors.initials: R
authors.lastname: Möller
authors.forename: Barbara
authors.initials: B
authors.lastname: Seise
authors.forename: Andrea
authors.initials: A
authors.lastname: Csaki
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Fritzsche
authors.forename: Carsten
authors.initials: C
authors.lastname: Ronning