title: Coverage of gingival recession defects using acellular dermal matrix allograft with or without beta-tricalcium phosphate.
abstract: The aim of this study was to investigate the effect of beta-tricalcium phosphate (β-TCP) particles in combination with acellular dermal matrix (ADM) allograft in gingival recession. Experimental gingival recession defects were created in beagle dogs and randomly assigned to one of the following groups: ADM, ADM + β-TCP, or coronally positioned flap (CPF; control). Tissues were histologically examined at 4, 8, or 16 weeks following treatment. A greater thickness of gingiva was observed at the sites treated in both the ADM + β-TCP and ADM groups than in the CPF group. The ADM + β-TCP group showed a statistically significant increase in both new bone and cementum formations compared to the ADM group. The results suggest that the combination of β-TCP and ADM is more effective in promoting new bone and cementum formations than ADM graft alone.
authors.affiliation: Department of Periodontology, Tokyo Dental College, 1-2-2, Masago Mihama-ku, Chiba, 261-8502, Japan. ookubonobuki@tdc.ac.jp
authors.forename: Nobuki
authors.initials: N
authors.lastname: Okubo
authors.forename: Takahisa
authors.initials: T
authors.lastname: Fujita
authors.forename: Yoshihito
authors.initials: Y
authors.lastname: Ishii
authors.forename: Mikio
authors.initials: M
authors.lastname: Ota
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Shibukawa
authors.forename: Satoru
authors.initials: S
authors.lastname: Yamada
mesh_terms: D062088:Acellular Dermis; D000818:Animals; D002130:Calcium Phosphates; D004285:Dogs; D005889:Gingival Recession / Q000601:surgery*; D008297:Male; D014184:Transplantation, Homologous
chemical_list: D002130:Calcium Phosphates; C485817:beta-tricalcium phosphate