title: [Progress of TSC-22 gene research].
abstract: Transformation growth factor β -inducible gene 22 (TSC-22) is a putative negative growth regulation and tumor suppressor gene. It has the ability to combine with other transcription factors to regulate the cell growth and apoptosis. TSC-22 is lowly expressed in many types of tumors,which may be related to the tumorgenesis and development.
authors.affiliation: Cancer Research Institute, Central South University, Changsha 410078, China.
authors.forename: Shiming
authors.initials: S
authors.lastname: Tan
authors.forename: Guiyuan
authors.initials: G
authors.lastname: Li
mesh_terms: D000818:Animals; D016147:Genes, Tumor Suppressor; D006801:Humans; D016350:Leucine Zippers / Q000235:genetics; D009369:Neoplasms / Q000503:physiopathology*; D012097:Repressor Proteins / Q000235:genetics* / Q000502:physiology*; D014157:Transcription Factors
chemical_list: D012097:Repressor Proteins; C099726:TSC22D1 protein, human; D014157:Transcription Factors