title: Different cognitive profiles of Brazilian patients with relapsing-remitting and primary progressive multiple sclerosis.
abstract: Cognitive impairment is a symptom of multiple sclerosis (MS). Different clinical forms of multiple sclerosis have different cognitive profiles, according to findings of previous studies which used extensive batteries of neuropsychological tests.
  
  
  OBJECTIVE
  To investigate cognitive profiles of Brazilian patients with relapsing-remitting multiple sclerosis (RRMS) and primary progressive multiple sclerosis (PPMS) by using a brief battery of neuropsychological tests.
  
  
  METHODS
  Sixty-six patients, within 18-65 of age and 3-18 years of education, were paired with healthy control subjects, regarding gender, age, and education level.
  
  
  RESULTS
  On Symbol Digit Modalities Test and Hooper Visual Organization Test, cognition was affected in 50% in RRMS and 69% in PPMS. Fluency of "F" was impaired in 24% of RRMS and 81% of PPMS. Immediate recall was affected in 32% of RRMS and in 63% of PPMS; whereas late recall, in 46% of relapsing-remitting and in 69% of primary progressive.
  
  
  CONCLUSIONS
  Cognitive profiles of relapsing-remitting and primary progressive patients are different.
authors.affiliation: Neurologia pela UNIRIO, Trabalho desenvolvido no Programa de Pós-Graduação em Neurologia, Universidade Federal do Estado do Rio de Janeiro (UNIRIO), Rio de Janeiro RJ, Brazil.
authors.forename: Dóra-Neide
authors.initials: DN
authors.lastname: Rodrigues
authors.forename: Renata Alves
authors.initials: RA
authors.lastname: Paes
authors.forename: Claudia Cristina Ferreira
authors.initials: CC
authors.lastname: Vasconcelos
authors.forename: Jesus
authors.initials: J
authors.lastname: Landeira-Fernandez
authors.forename: Maria Papais
authors.initials: MP
authors.lastname: Alvarenga
mesh_terms: D000328:Adult; D000368:Aged; D016022:Case-Control Studies; D003072:Cognition Disorders / Q000209:etiology*; D004522:Educational Status; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D020528:Multiple Sclerosis, Chronic Progressive / Q000150:complications*; D020529:Multiple Sclerosis, Relapsing-Remitting / Q000150:complications*; D009483:Neuropsychological Tests; D012720:Severity of Illness Index; D055815:Young Adult