title: [Influence of alpha-lipoic acid on liver glutathione system of healthy and Ehrlich ascites carcinoma transplanted mice].
abstract: Influence of alpha-lipoic acid (LA) on liver glutathione system of Ehrlich ascites carcinoma (EAC) transplanted mice was studied. LA causes multidirectional influence on glutathione system of healthy mice. EAC transforms LA influence, strengthening prooxidative effects more expressed at introduction in early terms after inoculation of the tumor. The mechanism explaining realization of LA prooxidative effects as a result of interaction with glutathione system is suggested.
authors.forename: L S
authors.initials: LS
authors.lastname: Kolesnichenko
authors.forename: V S
authors.initials: VS
authors.lastname: Laletin
authors.forename: V I
authors.initials: VI
authors.lastname: Kulinskiĭ
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000494:pharmacology*; D002286:Carcinoma, Ehrlich Tumor / Q000378:metabolism*; D005978:Glutathione / Q000378:metabolism*; D008099:Liver / Q000378:metabolism*; D051379:Mice; D009368:Neoplasm Transplantation; D010084:Oxidation-Reduction / Q000187:drug effects; D008063:Thioctic Acid / Q000494:pharmacology*
chemical_list: D000975:Antioxidants; D008063:Thioctic Acid; D005978:Glutathione