title: The challenge of profound hypoglycorrhachia: two cases of sarcoidosis and review of the literature.
abstract: We report two cases of sarcoidosis which were initially misdiagnosed due to profound hypoglycorrhachia. Sarcoidosis is a systemic inflammatory disorder which can mimick other entities and has a vast array of presentations including altered mentation and signs of increased intracranial pressure. Though hypoglycorrhachia has been described previously, these two cases are unique in not only the level of hypoglycorrhachia but also the diagnostic challenge presented. We propose that sarcoidosis should be in the differential of all cases of CNS diseases with any level of hypoglycorrhachia.
authors.affiliation: SUNY Downstate Medical Center, 450 Clarkson Avenue, Brooklyn, NY 11203, USA. harini.rao@downstate.edu
authors.forename: Harini
authors.initials: H
authors.lastname: Sarva
authors.forename: Rachel
authors.initials: R
authors.lastname: Chapman
authors.forename: Eghosa
authors.initials: E
authors.lastname: Omoregie
authors.forename: Charles
authors.initials: C
authors.lastname: Abrams
mesh_terms: D000328:Adult; D001706:Biopsy; D003937:Diagnosis, Differential; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D005947:Glucose / Q000134:cerebrospinal fluid*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D010900:Pituitary Diseases / Q000134:cerebrospinal fluid / Q000175:diagnosis* / Q000188:drug therapy; D011241:Prednisone / Q000627:therapeutic use; D012507:Sarcoidosis / Q000134:cerebrospinal fluid / Q000175:diagnosis* / Q000188:drug therapy; D014390:Tuberculosis, Meningeal / Q000134:cerebrospinal fluid / Q000175:diagnosis* / Q000188:drug therapy
chemical_list: D005938:Glucocorticoids; D005947:Glucose; D011241:Prednisone