title: Long-term follow-up after robotic thymectomy for nonthymomatous myasthenia gravis.
abstract: BACKGROUND
  Thymectomy is recognized as a significant component in the treatment of myasthenia gravis. However, controversy exists as to the optimal surgical approach. This investigation summarizes our experience performing extended thymectomy using a robotic technique in a large group of patients with significant follow-up.
  
  
  METHODS
  Data collection for patients undergoing robotic thymectomy for nonthymomatous myasthenia gravis over a 6-year period was prospectively performed. Patients were assessed using the Myasthenia Gravis Foundation of America's quantitative disease severity score and the post intervention status classification.
  
  
  RESULTS
  During the study period, 75 patients underwent thymectomy by this method. Mean preoperative myasthenia gravis severity score was 2.7. Mean operative time was 113±46 minutes. Extubation in the operating room occurred in 73 (98%) patients. Mean intensive care stay and total hospital length of stay were 0.9 and 2.2 days respectively. Mean interval between surgery and return to work (or prethymectomy activities of daily living) was 15±6 days. Significant improvement of myasthenia gravis symptoms occurred in 65 (87%) patients with a mean follow-up of 45±14 months.
  
  
  CONCLUSIONS
  Robotic-assisted thymectomy is a safe and effective technique for patients with symptomatic myasthenia gravis. It allowed an extended thymectomy to be performed without the associated length of stay or recovery period of a transsternal approach while producing comparable rates of symptom improvement.
authors.affiliation: Department of Thoracic and Cardiovascular Surgery, St. Vincent Hospital, Indianapolis, Indiana 46260, USA. rfreeman@corvascmds.com
authors.forename: Richard K
authors.initials: RK
authors.lastname: Freeman
authors.forename: Anthony J
authors.initials: AJ
authors.lastname: Ascioti
authors.forename: Jaclyn M
authors.initials: JM
authors.lastname: Van Woerkom
authors.forename: Amy
authors.initials: A
authors.lastname: Vyverberg
authors.forename: Robert J
authors.initials: RJ
authors.lastname: Robison
mesh_terms: D000293:Adolescent; D000328:Adult; D018450:Disease Progression; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D009157:Myasthenia Gravis / Q000175:diagnosis / Q000601:surgery*; D011446:Prospective Studies; D012371:Robotics / Q000379:methods*; D012720:Severity of Illness Index; D013934:Thymectomy / Q000379:methods*; D013997:Time Factors; D016896:Treatment Outcome; D055815:Young Adult