title: Squamous cell carcinoma arising in a mature cystic ovarian teratoma with bladder invasion: a case report.
abstract: BACKGROUND
  Malignant transformation in a mature cystic ovarian teratoma is rare. Except in cases with high index of suspicion or overt metastasis, oophorectomy is the mainstay of treatment for ovarian teratoma.
  
  
  METHODS
  A 46-year-old perimenopausal woman who had salpingo-oophorectomy following a clinical diagnosis of benign ovarian tumour that was subsequently reported histologically as mature cystic ovarian teratoma with malignant transformation is presented.
  
  
  RESULTS
  She was referred to our facility based on the histopathology report and haematuria two weeks after surgery. Cystoscopic biopsy done was reported as metastatic squamous cell carcinoma most probably from the ovary. Patient was thereafter referred for radiotherapy but was lost to follow-up after the first course.
  
  
  CONCLUSIONS
  Adequate evaluation prior to surgery in suspected ovarian teratoma with malignant transformation is critical to determine extent of surgery and adjuvant therapy. Prognosis in advanced disease condition such as the case presented is generally poor although radical pelvic surgery with resection of the adjacent involved bladder before radiotherapy would probably have improved her prognosis.
authors.affiliation: Department of Pathology, College of Health Sciences, University of Ilorin, Nigeria. badmoskb@yahoo.com
authors.forename: K B
authors.initials: KB
authors.lastname: Badmos
authors.forename: O K
authors.initials: OK
authors.lastname: Ibrahim
authors.forename: A P
authors.initials: AP
authors.lastname: Aboyeji
authors.forename: J A
authors.initials: JA
authors.lastname: Omotayo
mesh_terms: D000328:Adult; D001706:Biopsy; D002294:Carcinoma, Squamous Cell / Q000473:pathology*; D002471:Cell Transformation, Neoplastic / Q000473:pathology*; D003558:Cystoscopy; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D059012:Lost to Follow-Up; D009367:Neoplasm Staging; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D010051:Ovarian Neoplasms / Q000473:pathology*; D013724:Teratoma / Q000473:pathology*; D001749:Urinary Bladder Neoplasms / Q000473:pathology*