title: Stereospecific synthesis of new steroidal isoxazoles in dry media.
abstract: An easy and fast procedure was developed for one-pot synthesis of steroidal isoxazoles starting from 23-acetylsapogenins derivatives in presence of P2O5/SiO2 in dry media under microwaves irradiation is described. Substrates of the 25S and 25R series were used as raw materials, establishing that this new methodology is applicable to both series.
authors.affiliation: Escuela de Ingeniería en Petróleos e Ingeniería Química, Universidad del Istmo, Ciudad Universitaria S/N, C.P. 70760 Sto. Domingo Tehuantepec, Oax., Mexico. maguhdez@sandunga.unistmo.edu.mx
authors.forename: María Guadalupe
authors.initials: MG
authors.lastname: Hernández-Linares
authors.forename: Jesús
authors.initials: J
authors.lastname: Sandoval-Ramírez
authors.forename: Socorro
authors.initials: S
authors.lastname: Meza-Reyes
authors.forename: Sara
authors.initials: S
authors.lastname: Montiel-Smith
authors.forename: Gabriel
authors.initials: G
authors.lastname: Guerrero-Luna
mesh_terms: D060326:Chemistry Techniques, Synthetic / Q000379:methods*; D007555:Isoxazoles / Q000737:chemistry*; D008872:Microwaves; D012502:Sapogenins / Q000737:chemistry; D013237:Stereoisomerism; D013256:Steroids / Q000138:chemical synthesis* / Q000737:chemistry*; D013379:Substrate Specificity
chemical_list: D007555:Isoxazoles; D012502:Sapogenins; D013256:Steroids