title: Measuring SeHCAT retention: a technical note.
abstract: TauroH-23-((75)Se)selena-25-homocholic acid (SeHCAT) retention has been used for the diagnosis of bile acid malabsorption since the early 1980s. Bile acid malabsorption has been increasingly recognized as an important cause of severe chronic diarroea with subsequent increase in the number of referrals for the SeHCAT test. In this study, we review and discuss the standard techniques for the measurement of SeHCAT retention and describe a simple and modified technique using a noncollimated whole-body scanner, suitable for most modern dual-headed cameras.
authors.affiliation: Departments of Physics and Nuclear Medicine at City Hospital, Sandwell and West Birmingham Hospitals NHS Trust, Birmingham, UK. alp.notghi@swbh.nhs.uk
authors.forename: Alp
authors.initials: A
authors.lastname: Notghi
authors.forename: Joseph
authors.initials: J
authors.lastname: O'Brien
authors.forename: Chen Sheng
authors.initials: CS
authors.lastname: Low
authors.forename: William
authors.initials: W
authors.lastname: Thomson
mesh_terms: D006801:Humans; D015203:Reproducibility of Results; D013656:Taurocholic Acid / Q000031:analogs & derivatives* / Q000493:pharmacokinetics; D051598:Whole Body Imaging / Q000295:instrumentation / Q000379:methods*
chemical_list: D013656:Taurocholic Acid; C033638:23-seleno-25-homotaurocholic acid