title: Cardiac myxoma in Iceland: a case series with an estimation of population incidence.
abstract: Cardiac myxoma (CM) is the most common primary benign tumor of the heart, but the true age-standardized incidence rate (ASR) has remained unknown. We therefore used nationwide registries in Iceland to study CM and establish its incidence rate. This was a retrospective study involving all patients diagnosed with CM in Iceland between 1986 and 2010. Cases were identified through three different registries, and hospital charts and histology results reviewed. An ASR was estimated based on a world standard population (w). Nine cases of CM (six women) were identified with a mean age of 62.8 years (range: 37-85), giving an ASR of 0.11 (95% CI: 0.05-0.22) per 100,000. The mean tumor size was 4.4 cm (range: 1.5-8.0) with all the tumors located in the left atrium. Dyspnea (n = 6) and ischemic stroke (n = 2) were the most common symptoms. All patients underwent complete resection of the tumor and there were no postoperative deaths or CM-related deaths at follow-up (mean 85 months). The ASR of CM in Iceland was 0.11 per 100,000. To our knowledge, this is the first study to determine the incidence of CM in an entire population. In Iceland, the presenting symptoms and mode of detection of CM are similar to those in other series.
authors.affiliation: Departments of Cardiothoracic Surgery.|Faculty of Medicine, University of Iceland, Reykjavik, Iceland.
authors.forename: Hannes
authors.initials: H
authors.lastname: Sigurjonsson
authors.affiliation: Cardiology.|Faculty of Medicine, University of Iceland, Reykjavik, Iceland.
authors.forename: Karl
authors.initials: K
authors.lastname: Andersen
authors.affiliation: Radiology.
authors.forename: Marianna
authors.initials: M
authors.lastname: Gardarsdottir
authors.affiliation: Pathology.
authors.forename: Vigdis
authors.initials: V
authors.lastname: Petursdottir
authors.affiliation: Anaesthesia & Intensive Care at Landspitali University Hospital.
authors.forename: Gudmundur
authors.initials: G
authors.lastname: Klemenzson
authors.affiliation: Department of Internal Medicine, Akureyri Hospital.|Faculty of Medicine, University of Iceland, Reykjavik, Iceland.
authors.forename: Gunnar
authors.initials: G
authors.lastname: Gunnarsson
authors.affiliation: Cardiology.
authors.forename: Ragnar
authors.initials: R
authors.lastname: Danielsen
authors.affiliation: Departments of Cardiothoracic Surgery.|Faculty of Medicine, University of Iceland, Reykjavik, Iceland.
authors.forename: Tomas
authors.initials: T
authors.lastname: Gudbjartsson
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005500:Follow-Up Studies; D006325:Heart Atria; D006338:Heart Neoplasms / Q000175:diagnosis / Q000453:epidemiology* / Q000601:surgery; D006801:Humans; D007055:Iceland / Q000453:epidemiology; D015994:Incidence; D008297:Male; D008875:Middle Aged; D009232:Myxoma / Q000175:diagnosis / Q000453:epidemiology* / Q000601:surgery; D012042:Registries; D012189:Retrospective Studies