title: Unusual sites of extrapulmonary metastases of osteosarcoma after several lines of treatment.
abstract: The authors report a case of peritoneal and chest wall metastases in a 17-year-old boy previously diagnosed of femur osteosarcoma with metastases in the lung and bones. Although the patient achieved complete remission after initial treatment, he presented with lung metastasis 15 months after initial diagnosis. They were resected 3 times and he received second-line chemotherapy with gemcitabine and docetaxel. However, 31 months after initial diagnosis he presented with abdominal and chest wall masses. In this report the authors discuss clinical outcomes and how unusual sites of metastasis are being increasingly reported after the use of new treatments.
authors.affiliation: Department of Hemato-Oncology and Stem Cell Transplantation, Hospital Infantil Universitario Niño Jesús, Av. Menéndez Pelayo 65, Madrid, Spain. gonorootero@hotmail.com
authors.forename: Gonzalo
authors.initials: G
authors.lastname: Oñoro
authors.forename: Carmen
authors.initials: C
authors.lastname: Hernández
authors.forename: Sara
authors.initials: S
authors.lastname: Sirvent
authors.forename: Esther
authors.initials: E
authors.lastname: Aleo
authors.forename: Blanca
authors.initials: B
authors.lastname: Molina
authors.forename: Alvaro Lassaletta
authors.initials: AL
authors.lastname: Atienza
authors.forename: Antonio
authors.initials: A
authors.lastname: Pérez-Martínez
mesh_terms: D000293:Adolescent; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D017809:Fatal Outcome; D005266:Femoral Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy*; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis / Q000556:secondary* / Q000628:therapy; D008297:Male; D012516:Osteosarcoma / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy*