title: [Comparative study of periprostatic tissues thickness after retropubic or laparoscopic radical prostatectomy].
abstract: OBJECTIVE
  Analysing periprostatic tissue (PPT) thickness after retropubic (RP) or laparoscopic (LP) prostatectomy.
  
  
  METHODS
  From January to December 2007, 114 consecutives prostatectomies were performed in our institution (38 RP, 76 LP). Clinical data were prospectively collected in a database. Gardner et al.'s (1988) procedure was used for pathological analysis. PPT thickness was measured on pathological specimens by a single observer on a single microscope. The observer had no knowledge of either clinical data or surgical approach. Four levels were chosen (at the base, the proximal part, the distal part, the apex) and 12 standardized measures were performed on each level, 48 measures: a prostate. We compared PPT thickness and surgical margins according to surgical approach and clinical data.
  
  
  RESULTS
  Comparative analysis confirmed that LP and RP groups were similar as far as it concerns preoperative and pathological findings. Positive margin rate was also similar in LP and RP groups (4% versus 5.3%; P=0,37). Overall PPT thickness was thinner after LP than after RP except at the apex and the anterior face. Nevertheless, in the "complete preservation" group, PPT thickness was thinner at the apex in the RP group, thinner at the base in the LP group.
  
  
  CONCLUSIONS
  Measuring PPT thickness was an original objective and reproducible way to compare different techniques and new technologies for radical prostatectomy. PPT sparing was different but not better with the laparoscopic approach.
authors.affiliation: Service d'Urologie, CHU Pellegrin, Place Amélie-Raba-Léon, 33076 Bordeaux, France. seb.barbet@gmail.com
authors.forename: S
authors.initials: S
authors.lastname: Barbet
authors.forename: G
authors.initials: G
authors.lastname: Robert
authors.forename: C
authors.initials: C
authors.lastname: Deminière
authors.forename: S
authors.initials: S
authors.lastname: Maurice-Tison
authors.forename: J-M
authors.initials: JM
authors.lastname: Ferrière
mesh_terms: D000368:Aged; D006801:Humans; D010535:Laparoscopy; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011467:Prostate / Q000473:pathology*; D011468:Prostatectomy / Q000379:methods; D011471:Prostatic Neoplasms / Q000473:pathology* / Q000601:surgery*