title: Premature labour precipitated by highly active antiretroviral therapy: an adverse reaction in a newly diagnosed HIV-positive patient.
abstract: A pregnant woman was diagnosed with HIV infection at 29 weeks' gestation. Antiretroviral therapy (ART) of lopinavir-ritonavir and zidovudine-lamivudine was initiated. Ten days later, a hypersensitivity reaction occurred, followed by preterm delivery of the infant 3 days later at 30 weeks' gestation. Hypersensitivity reactions to ART should prompt urgent consideration of a change in ART to avoid the potential for adverse pregnancy outcomes.
authors.affiliation: Department of Infectious Diseases, Nambour General Hospital, Nambour, Qld 4560, Australia. jenniferkbroom@gmail.com
authors.forename: Jennifer
authors.initials: J
authors.lastname: Broom
authors.forename: David
authors.initials: D
authors.lastname: Sowden
mesh_terms: D000328:Adult; D023241:Antiretroviral Therapy, Highly Active / Q000009:adverse effects*; D003875:Drug Eruptions / Q000175:diagnosis*; D005260:Female; D015658:HIV Infections / Q000188:drug therapy*; D006801:Humans; D007231:Infant, Newborn; D007752:Obstetric Labor, Premature / Q000139:chemically induced*; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000188:drug therapy*; D012307:Risk Factors; D019562:Viral Load