title: Epidemiology of candidemia in Songklanagarind Hospital.
abstract: OBJECTIVE
  To study the epidemiology of candidemia patients in Songklanagarind Hospital.
  
  
  METHODS
  A retrospective study examining the epidemiological data of candidemia patients in Songklanagarind Hospital, a referral center in southern Thailand, between January 2004 and December 2009.
  
  
  RESULTS
  Two hundred six candidemia inpatients had an overall 54% mortality rate. The median age of the patients was 53 years (range: 1-98 years). Length of hospital stay was an average of 55 days. Most of them (129, 62.6%) were admitted in a non-intensive care unit (non-ICU). The most common associated condition was solid organ malignancy (67, 32.5%). Most of the patients (181, 88%) had a history of broad spectrum antibiotic usage; however, in the non-broad spectrum antibiotics group solid organ malignancy was still the most common associated condition. Candida albicans and non-albicans Candida accounted for 83 (40.3%) and 123 (59.7%) cases, respectively. Higher mortality rates were significantly related with intensive care unit (ICU) admission, elderly patients, and the presence of solid organ tumors, hematologic malignancies, and neutropenia, and influenced by intubation with a mechanical ventilator, central venous or urethral catheterization, surgical procedures, and administration of antibiotics.
  
  
  CONCLUSIONS
  Candidemia can cause a high mortality rate that is influenced with many independent risk factors including surgical and medical interventions. Non-albicans Candida is more common than Candida albicans whereas each mortality rate was not significantly different.
authors.affiliation: Department of Medicine, Faculty of Medicine, Prince of Songkla University, Songkhla, Thailand.
authors.forename: Noppawan
authors.initials: N
authors.lastname: Jutiamornlerd
authors.forename: Sarunyou
authors.initials: S
authors.lastname: Chusri
authors.forename: Pisud
authors.initials: P
authors.lastname: Siripaitoon
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D000935:Antifungal Agents / Q000627:therapeutic use; D002175:Candida / Q000145:classification / Q000302:isolation & purification*; D058387:Candidemia / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology / Q000401:mortality*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006784:Hospitals, Teaching; D006801:Humans; D007223:Infant; D007902:Length of Stay / Q000706:statistics & numerical data; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D012044:Regression Analysis; D012189:Retrospective Studies; D012307:Risk Factors; D017678:Sex Distribution; D013785:Thailand / Q000453:epidemiology; D055815:Young Adult
chemical_list: D000935:Antifungal Agents