title: CTX-M-9 group extended-spectrum β-lactamases in neonatal stool isolates: emergence in India.
abstract: The study reports for the first time the identification of CTX-M-14-like and CTX-M-27-like extended-spectrum β-lactamases (ESBLs) belonging to the CTX-M-9 group in Klebsiella pneumoniae and Escherichia coli isolated from the neonatal stool in India. The plasmid carrying the blaCTX-M-9 group in both the isolates was transferable. Till date, no other CTX-M group, except the CTX-M-1 group, has been reported from India. A total of 77% of the neonates had ESBL-producing K. pneumoniae or E. coli in their stool, and blaCTX-M-15 was the predominant ESBL gene. Although the CTX-M-9 group was found in the stool and did not cause infection, the detection of the CTX-M-9 group might be a prelude to future infections.
authors.affiliation: Division of Bacteriology, National Institute of Cholera and Enteric Diseases, P33, CIT Road, Scheme XM, Beliaghata, Kolkata - 700 010, India.
authors.forename: S
authors.initials: S
authors.lastname: Roy
authors.forename: S
authors.initials: S
authors.lastname: Mukherjee
authors.forename: A K
authors.initials: AK
authors.lastname: Singh
authors.forename: S
authors.initials: S
authors.lastname: Basu
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D004926:Escherichia coli / Q000187:drug effects / Q000201:enzymology* / Q000302:isolation & purification*; D029968:Escherichia coli Proteins / Q000378:metabolism*; D005243:Feces / Q000382:microbiology*; D022761:Gene Transfer, Horizontal; D006801:Humans; D007194:India; D007231:Infant, Newborn; D007711:Klebsiella pneumoniae / Q000187:drug effects / Q000201:enzymology* / Q000302:isolation & purification*; D008826:Microbial Sensitivity Tests; D001618:beta-Lactamases / Q000378:metabolism*
chemical_list: D000900:Anti-Bacterial Agents; D029968:Escherichia coli Proteins; C412613:CTX-M-9 protein, E coli; D001618:beta-Lactamases