title: Treatment of chronic pulmonary blastomycosis with caspofungin.
abstract: Current practice guidelines recommend that pulmonary blastomycosis be treated with antifungal agents such as amphotericin B and itraconazole. Echinocandins are not recommended because of poor in vitro activity against Blastomyces dermatitidis and lack of supporting clinical data. We report a case of chronic pulmonary blastomycosis treated successfully with caspofungin.
authors.affiliation: University of Montréal, Montréal, Canada.
authors.forename: Joëlle
authors.initials: J
authors.lastname: Mardini
authors.affiliation: Department of Pneumology, Sacré-Coeur Hospital, Montréal, Canada.
authors.forename: Bich
authors.initials: B
authors.lastname: Nguyen
authors.affiliation: Department of Medicine, Verdun Hospital, Montréal, Canada.
authors.forename: Marc
authors.initials: M
authors.lastname: Ghannoum
authors.affiliation: Department of Anatomic Pathology and Cytology, Institut Universitaire de Cardiologie et de Pneumologie de Québec (Hôpital Laval), Québec, Canada.
authors.forename: Christian
authors.initials: C
authors.lastname: Couture
authors.affiliation: Department of Medical Microbiology and Infectious Diseases, Sacré-Coeur Hospital, Montréal, Canada.
authors.forename: Valéry
authors.initials: V
authors.lastname: Lavergne
mesh_terms: D000328:Adult; D000935:Antifungal Agents / Q000627:therapeutic use*; D001758:Blastomyces / Q000187:drug effects*; D001759:Blastomycosis / Q000188:drug therapy* / Q000382:microbiology; D000077336:Caspofungin; D054714:Echinocandins / Q000627:therapeutic use*; D006801:Humans; D055666:Lipopeptides; D008172:Lung Diseases, Fungal / Q000188:drug therapy* / Q000382:microbiology; D008297:Male
chemical_list: D000935:Antifungal Agents; D054714:Echinocandins; D055666:Lipopeptides; D000077336:Caspofungin