title: Is there a place for AMH testing in Canada?
abstract: Anti-müllerian hormone (AMH) is a glycoprotein traditionally known for its role in male sexual differentiation. More recently, AMH has been studied for its role in ovarian folliculogenesis and as a potential marker of ovarian reserve. A number of studies have suggested that measurement of serum AMH is a superior test of ovarian reserve because it is highly associated with the number of antral follicles, has little cycle variability, and declines throughout the reproductive lifespan. There is also evidence supporting the ability of AMH levels to predict age of menopause. Other studies have shown that measurement of serum AMH can predict responsiveness to ovarian follicular stimulation and the risk for ovarian hyperstimulation syndrome in women undergoing in vitro fertilization. Given the variety of potential applications and favourable test characteristics, it is reasonable to ask whether there is a place for providing universal AMH testing in Canada.
authors.affiliation: Department of Medicine, Dalhousie University, Halifax NS.
authors.forename: Jordan A
authors.initials: JA
authors.lastname: Green
authors.affiliation: Department of Obstetrics and Gynaecology, IWK Health Centre, Dalhousie University, Halifax NS.
authors.forename: Gillian
authors.initials: G
authors.lastname: Graves
mesh_terms: D000328:Adult; D000818:Animals; D054304:Anti-Mullerian Hormone / Q000097:blood* / Q000502:physiology; D002170:Canada; D005260:Female; D006801:Humans; D008593:Menopause; D051379:Mice; D010053:Ovary / Q000502:physiology; D011085:Polycystic Ovary Syndrome; D011247:Pregnancy; D011256:Pregnancy Outcome; D012098:Reproduction / Q000502:physiology
chemical_list: D054304:Anti-Mullerian Hormone