title: Acute effect of soybean beta-conglycinin hydrolysate ingestion on appetite sensations in healthy humans.
abstract: A hydrolysate prepared from soybean beta-conglycinin reduced food intake through cholecystokinin release in rats; however, effects of the hydrolysate on human appetites are unknown. In this study, healthy volunteers ingested 3g of the beta-conglycinin hydrolysate (BconB) and/or a soy protein hydrolysate (HN) contained in a beverage or in a jelly. Appetite profiles (hunger, fullness and prospective consumption) after the ingestion and palatability of test jellies were recorded. Fullness was rated higher, and hunger was rated lower after BconB ingestion as compared to HN ingestion. These results demonstrate that 3g of BconB is effective to enhance fullness and reduce hunger sensations in healthy humans.
authors.affiliation: Laboratory of Nutritional Biochemistry, Research Faculty of Agriculture, Hokkaido University, Kita-9, Nishi-9, Kita-ku, Sapporo 060-8589, Japan. hira@chem.agr.hokudai.ac.jp
authors.forename: Tohru
authors.initials: T
authors.lastname: Hira
authors.forename: Naomi
authors.initials: N
authors.lastname: Mori
authors.forename: Toshihiro
authors.initials: T
authors.lastname: Nakamori
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Furuta
authors.forename: Kozo
authors.initials: K
authors.lastname: Asano
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Chiba
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Hara
mesh_terms: D000328:Adult; D000818:Animals; D052179:Antigens, Plant / Q000494:pharmacology*; D001066:Appetite / Q000187:drug effects*; D002766:Cholecystokinin / Q000378:metabolism; D004435:Eating; D002149:Energy Intake / Q000187:drug effects; D005260:Female; D005916:Globulins / Q000494:pharmacology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010936:Plant Extracts / Q000494:pharmacology*; D011446:Prospective Studies; D011492:Protein Hydrolysates / Q000494:pharmacology*; D051381:Rats; D012527:Satiation / Q000187:drug effects; D055314:Seed Storage Proteins / Q000494:pharmacology*; D030262:Soybean Proteins / Q000494:pharmacology*; D013025:Glycine max / Q000737:chemistry; D055815:Young Adult
chemical_list: D052179:Antigens, Plant; D005916:Globulins; D010936:Plant Extracts; D011492:Protein Hydrolysates; D055314:Seed Storage Proteins; D030262:Soybean Proteins; C013894:beta-conglycinin protein, Glycine max; D002766:Cholecystokinin