title: NMO-DBr: the Brazilian Neuromyelitis Optica Database System.
abstract: OBJECTIVE
  To present the Brazilian Neuromyelitis Optica Database System (NMO-DBr), a database system which collects, stores, retrieves, and analyzes information from patients with NMO and NMO-related disorders.
  
  
  METHODS
  NMO-DBr uses Flux, a LIMS (Laboratory Information Management Systems) for data management. We used information from medical records of patients with NMO spectrum disorders, and NMO variants, the latter defined by the presence of neurological symptoms associated with typical lesions on brain magnetic resonance imaging (MRI) or aquaporin-4 antibody seropositivity.
  
  
  RESULTS
  NMO-DBr contains data related to patient's identification, symptoms, associated conditions, index events, recurrences, family history, visual and spinal cord evaluation, disability, cerebrospinal fluid and blood tests, MRI, optic coherence tomography, diagnosis and treatment. It guarantees confidentiality, performs cross-checking and statistical analysis.
  
  
  CONCLUSIONS
  NMO-DBr is a tool which guides professionals to take the history, record and analyze information making medical practice more consistent and improving research in the area.
authors.affiliation: CIEM MS Research Center, Belo Horizonte MG, Brazil. marco.lanapma@gmail.com
authors.forename: Marco A
authors.initials: MA
authors.lastname: Lana-Peixoto
authors.forename: Lívia Edwiges
authors.initials: LE
authors.lastname: Talim
authors.forename: Alessandra C
authors.initials: AC
authors.lastname: Faria-Campos
authors.forename: Sérgio V A
authors.initials: SV
authors.lastname: Campos
authors.forename: Cristiane F
authors.initials: CF
authors.lastname: Rocha
authors.forename: Lucas A
authors.initials: LA
authors.lastname: Hanke
authors.forename: Natália
authors.initials: N
authors.lastname: Talim
authors.forename: Paulo Henrique
authors.initials: PH
authors.lastname: Batista
authors.forename: Carolina R
authors.initials: CR
authors.lastname: Araujo
authors.forename: Rodrigo
authors.initials: R
authors.lastname: Kleinpaul
mesh_terms: D001938:Brazil; D003628:Database Management Systems; D016208:Databases, Factual; D006801:Humans; D009471:Neuromyelitis Optica