title: Norovirus: an overview.
abstract: Although noroviruses (NoVs) were the first viral agents linked to gastrointestinal disease, for a long time they have been considered secondary cause of gastroenteritis, second to rotaviruses as etiologic agents. The development of molecular techniques in diagnosing NoV provided a clearer insight into the epidemiological impact of these viruses, which are currently recognized not only as the leading cause of non-bacterial gastroenteritis outbreaks, but also as a major cause of sporadic gastroenteritis in both children and adults. This review focuses on the required knowledge to understand their morphology, genetics, transmission, pathogenesis, and control. Since no vaccine is available, prevention of NoV infection relies mainly on strict community and personal hygiene measures.
authors.affiliation: Instituto Adolfo Lutz, Virology Center, Nucleus of Enteric Diseases, São Paulo, SP, Brazil.
authors.forename: Simone Guadagnucci
authors.initials: SG
authors.lastname: Morillo
authors.forename: Maria do Carmo Sampaio Tavares
authors.initials: Mdo C
authors.lastname: Timenetsky
mesh_terms: D017250:Caliciviridae Infections / Q000175:diagnosis* / Q000635:transmission; D003967:Diarrhea / Q000175:diagnosis / Q000821:virology; D005759:Gastroenteritis / Q000175:diagnosis* / Q000821:virology; D006801:Humans; D029322:Norovirus / Q000145:classification* / Q000472:pathogenicity*