title: [Sinus node activity in Parkinson's disease].
abstract: Results of evaluation of cardiac rhythm variability (CRV) in Parkinson's disease (PD) are presented. High-resolution rhythmocardiography with a KAP-RK-01-Mikor diagnostic system was used to register CRY, peripheral and autonomous dysregulation of pacemaker activity of the synoatrial node. Reduced CRV was documented in 107 PD patients of whom 26% exhibited synoatrial dysfunction. The temporal statistical and spectral analysis of CRV, comparison of its results with clinical data suggest dissociation between cerebral and peripheral vegetative effects in PD, relatively well preserved suprasegmental ergotropic regulatory afferent impacts, and inadequate vegetative control at the post-ganglionic level.
authors.forename: A F
authors.initials: AF
authors.lastname: Vasilenko
authors.forename: Iu S
authors.initials: IuS
authors.lastname: Shamurov
authors.forename: T F
authors.initials: TF
authors.lastname: Mironova
mesh_terms: D000328:Adult; D000368:Aged; D001145:Arrhythmias, Cardiac / Q000150:complications / Q000503:physiopathology*; D015716:Electrocardiography, Ambulatory / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006339:Heart Rate / Q000502:physiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000150:complications / Q000503:physiopathology*; D012189:Retrospective Studies; D012849:Sinoatrial Node / Q000503:physiopathology*