title: Antiphospholipid syndrome following toxoplasma retinochoroiditis.
abstract: OBJECTIVE
  To report a case of antiphospholipid syndrome (APS) following toxoplasma retinochoroiditis.
  
  
  METHODS
  Interventional case report.
  
  
  METHODS
  The patient was a 24-year-old female with an attack of visual loss due to toxoplasma retinochoroiditis concomitant with branch retinal vein occlusion. Retinitis resolved with anti-toxoplasma treatment. However, a recurrent episode of BRVO and vitreous hemorrhage occurred later.
  
  
  RESULTS
  In systemic evaluation, evidence of APS was detected, including high titers of anti-cardiolipin antibody, increased beta-2 microglobulin and anti-toxoplasma IgG antibody, and also low titers of C3, C4, and CH50.
  
  
  CONCLUSIONS
  Ocular toxoplasmosis should be included in the list of etiologies of secondary APS. Systemic evaluation for detection of APS is a necessary approach to patients with toxoplasma retinochoroiditis and concomitant vascular accident.
authors.affiliation: Ophthalmology Department and Ophthalmic Research Center, Labbafinejad Medical Center, Shahid Beheshti Medical University, Tehran, Iran.
authors.forename: Mehdi
authors.initials: M
authors.lastname: Tavakoli
authors.forename: Shiva
authors.initials: S
authors.lastname: Roghaee
authors.forename: Roham
authors.initials: R
authors.lastname: Soheilian
authors.forename: Masoud
authors.initials: M
authors.lastname: Soheilian
mesh_terms: D017153:Antibodies, Anticardiolipin / Q000097:blood; D016736:Antiphospholipid Syndrome / Q000209:etiology* / Q000276:immunology; D000981:Antiprotozoal Agents / Q000627:therapeutic use; D002825:Chorioretinitis / Q000150:complications* / Q000188:drug therapy / Q000276:immunology; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D012170:Retinal Vein Occlusion / Q000276:immunology / Q000469:parasitology; D014126:Toxoplasmosis, Ocular / Q000150:complications* / Q000188:drug therapy / Q000276:immunology; D055815:Young Adult; D001613:beta 2-Microglobulin / Q000097:blood
chemical_list: D017153:Antibodies, Anticardiolipin; D000981:Antiprotozoal Agents; D007074:Immunoglobulin G; D001613:beta 2-Microglobulin