title: Magnetic resonance spectroscopy of the canine brain at 3.0 T and 7.0 T.
abstract: The purpose of this study was to evaluate the feasibility of proton magnetic resonance spectroscopy (1H MRS) to study the concentration of metabolites in the brain of dogs at 3.0 and 7.0 T. Four healthy male beagles were scanned using 3.0 T and 7.0 T human magnetic resonance imaging (MRI) units. The results obtained showed that all dogs had excellent quality spectra for a small (1 cm3) and large (8 cm3) voxel at 3.0 T, whereas only 2 dogs had high quality spectra at 7.0 T due to insufficient water suppression. 1H MRS at 3.0 T appears to be a reliable method to study metabolite concentrations in the canine brain. The development of more advanced water suppression techniques is necessary to improve the results at 7.0 T.
authors.affiliation: Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Ohio State University, 601 Vernon L. Tharp Street, Columbus, OH 43210, USA. martin-vaquero.1@osu.edu
authors.forename: Paula
authors.initials: P
authors.lastname: Martin-Vaquero
authors.forename: Ronaldo C
authors.initials: RC
authors.lastname: da Costa
authors.forename: Rita L
authors.initials: RL
authors.lastname: Echandi
authors.forename: Christina L
authors.initials: CL
authors.lastname: Sammet
authors.forename: Michael V
authors.initials: MV
authors.lastname: Knopp
authors.forename: Steffen
authors.initials: S
authors.lastname: Sammet
mesh_terms: D000818:Animals; D001921:Brain / Q000033:anatomy & histology*; D004285:Dogs / Q000033:anatomy & histology; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D008297:Male; D059906:Neuroimaging / Q000379:methods / Q000662:veterinary*