title: Hypertensive patients show delayed wound healing following total hip arthroplasty.
abstract: BACKGROUND
  Prolonged wound-discharge following total hip arthroplasty (THA) is associated with an increased risk of infection. However, the potential role of hypertension in prolonging the duration of wound healing in this population has not yet been investigated. The aim of the present study was to compare healing in this population that has not yet been investigated. The aim of the present study was to compare hypertensive and normotensive THA patients in terms of the length of time required to achieve a dry wound and the length of stay in the hospital.
  
  
  METHODS
  One hundred and twenty primary THA patients were evaluated. Pre-operative clinical history and physical examination revealed that 29 were hypertensive and 91 were normotensive. The two groups were statistically matched using optimal propensity score matching. The outcomes of interest were the number of days until a dry wound was observed and the duration of hospital stay.
  
  
  RESULTS
  The average systolic blood pressures were 150.1 mmHg and 120.3 mmHg for the hypertensive and normotensive groups, respectively. The mean number of days until the wound was dry was 3.79 for the hypertensive group and 2.03 for the normotensive group. Hypertensive patients required more days for their wounds to dry than normotensive patients (odds ratio  =  1.65, p<0.05). No significant difference in the duration of hospital stay was found between the two groups.
  
  
  CONCLUSIONS
  Hypertensive patients had a higher risk of prolonged wound discharge after THA than their normotensive counterparts. Patients with prolonged wound drainage are at greater risk for infection. Clinicians should pay particular attention to infection-prevention strategies in hypertensive THA patients.
authors.affiliation: Temple University School of Medicine, Philadelphia, Pennsylvania, United States of America. awad.ahmed@temple.edu
authors.forename: Awad A
authors.initials: AA
authors.lastname: Ahmed
authors.forename: Pekka A
authors.initials: PA
authors.lastname: Mooar
authors.forename: Matthew
authors.initials: M
authors.lastname: Kleiner
authors.forename: Joseph S
authors.initials: JS
authors.lastname: Torg
authors.forename: Curtis T
authors.initials: CT
authors.lastname: Miyamoto
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D019644:Arthroplasty, Replacement, Hip; D001794:Blood Pressure; D005260:Female; D006801:Humans; D006973:Hypertension / Q000473:pathology* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D014945:Wound Healing