title: Simple and efficient nickel-catalyzed cross-coupling reaction of alkynylalanes with benzylic and aryl bromides.
abstract: Highly efficient and simple coupling reactions of benzylic and aryl bromides with aluminium acetylide catalyzed by NiCl(2)(PPh(3))(2) are reported. The coupling reactions proceed at room temperature employing 4 mol% catalyst, affording coupling products in excellent yields of up to 95% in short reaction times. The system worked efficiently with aryl and heterocyclic bromides as well.
authors.affiliation: Department of Chemistry, National Chung Hsing University, Taichung, 402, Taiwan.
authors.forename: Deepak B
authors.initials: DB
authors.lastname: Biradar
authors.forename: Han-Mou
authors.initials: HM
authors.lastname: Gau