title: [Current standards in the treatment of breast cancer].
abstract: Breast cancer is the most frequent malignoma in female individuals: more than 10 out 100 females suffer from the disease. The understanding of breast cancer as a primarily local disease has undergone a fundamental change in the last few decades. While throughout most of the previous century breast cancer was still mainly conceived of as a predominantly local disease, the radical nature of surgery can now be reduced to a minimum by the use of breast conserving procedures and axillary sentinel lymph node excision. The systemic use of cytostatic and endocrine therapeutic modalities has simultaneously provided a major overall survival benefit for patients treated in accordance with current therapeutic standards. The multidisciplinary treatment challenge of breast cancer comprises nowadays surgery, systemic treatment and radiotherapy and aims to a more individualized therapy.
authors.affiliation: Frauenklinik der Heinrich-Heine-Universität Düsseldorf, Moorenstrasse 5, 40225 Düsseldorf.
authors.forename: Karin
authors.initials: K
authors.lastname: Zwiefel
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Janni
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use; D018931:Antineoplastic Agents, Hormonal / Q000627:therapeutic use; D001943:Breast Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery / Q000628:therapy*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008197:Lymph Node Excision; D008207:Lymphatic Metastasis; D015412:Mastectomy, Segmental; D021701:Sentinel Lymph Node Biopsy
chemical_list: D000970:Antineoplastic Agents; D018931:Antineoplastic Agents, Hormonal