title: Palladium-catalyzed Heck reaction of aryl chlorides under mild conditions promoted by organic ionic bases.
abstract: An efficient Pd-catalyzed Heck reaction of aryl chlorides with olefins under mild conditions is described. High yields of products were achieved with n-Bu(4)N(+)OAc(-) as base. Significantly, the temperature of the Heck reaction of diverse nonactivated aryl chlorides can be lowered to 80 °C. The new reaction system can also tolerate a wider range of olefins.
authors.affiliation: School of Medical Engineering, Hefei University of Technology, Hefei 230009, PR China. hjxu@hfut.edu.cn
authors.forename: Hua-Jian
authors.initials: HJ
authors.lastname: Xu
authors.forename: Yong-Qiang
authors.initials: YQ
authors.lastname: Zhao
authors.forename: Xin-Feng
authors.initials: XF
authors.lastname: Zhou
mesh_terms: D001547:Benzaldehydes / Q000737:chemistry; D002384:Catalysis; D006841:Hydrocarbons, Aromatic / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*; D013696:Temperature
chemical_list: D001547:Benzaldehydes; D006841:Hydrocarbons, Aromatic; D010165:Palladium; C032175:benzaldehyde