title: [Current laboratory methods to evaluate the efficiency of immunization against dangerous and extremely dangerous infections].
abstract: By taking into account the leading role of specific cellular immunity in the development of protection against the majority of dangerous and extremely dangerous infections of bacterial, viral, and rickettsial nature, the study of the above immunity should be considered as most important on estimating the body's immunological rearrangement when vaccines against respective infections are administered. The battery of the test used to date for the analysis of specific cellular immunity is mainly restricted to skin tests that have disadvantages. This paper reviews the currently available laboratory methods for in vitro studies of a specific cellular immune response as a criterion for evaluating the efficiency of immunization.
authors.forename: N V
authors.initials: NV
authors.lastname: Bogacheva
authors.forename: I V
authors.initials: IV
authors.lastname: Darmov
authors.forename: G D
authors.initials: GD
authors.lastname: Elagin
authors.forename: A V
authors.initials: AV
authors.lastname: Kriuchkov
authors.forename: O V
authors.initials: OV
authors.lastname: Tikhvinskaia
mesh_terms: D001424:Bacterial Infections / Q000517:prevention & control*; D006801:Humans; D007111:Immunity, Cellular; D007159:Immunologic Tests / Q000379:methods*; D014611:Vaccination; D014612:Vaccines / Q000008:administration & dosage*; D014777:Virus Diseases / Q000517:prevention & control*
chemical_list: D014612:Vaccines