title: Characteristics of sodium sensitivity in Korean populations.
abstract: Sodium sensitivity (SS) is a variable response of blood pressure (BP) to changes in sodium intake. The present study evaluated the existence and the characteristics of subjects with SS in Koreans. One hundred one subjects with (n = 31, 57.7 ± 9.8 yr) or without hypertension (n = 70, 40.8 ± 16.5 yr) were given a low-sodium dietary approache to stop hypertension (DASH) diet (LSD) for 7 days and a high-sodium DASH diet (HSD) for the following 7 days. The prevalence of SS in the present study population was 27.7% (17.6% in the non-hypertensive subjects and 51.6% in the hypertensive subjects). Analysis of the non-hypertensive subjects showed that systolic BP, diastolic BP, and mean arterial pressure at baseline and after HSD were higher in the subjects with SS than the subjects without SS, and there were no differences after LSD. In the hypertensive subjects, there was no difference in the BP at baseline and after HSD whether or not the subjects had SS. However, the systolic BP of hypertensive subjects with SS was lower than hypertensive subjects without SS after LSD. In the present study population, subjects with SS have distinctive BP features unlike to subjects without SS.
authors.affiliation: Department of Internal Medicine, Dongguk University Ilsan Hospital, Dongguk University, Goyang, Korea.
authors.forename: Sung Joon
authors.initials: SJ
authors.lastname: Shin
authors.forename: Chi Yeon
authors.initials: CY
authors.lastname: Lim
authors.forename: Moo-Yong
authors.initials: MY
authors.lastname: Rhee
authors.forename: Sang Woo
authors.initials: SW
authors.lastname: Oh
authors.forename: Sang Hoon
authors.initials: SH
authors.lastname: Na
authors.forename: Yongsoon
authors.initials: Y
authors.lastname: Park
authors.forename: Cho-Il
authors.initials: CI
authors.lastname: Kim
authors.forename: Seo-Young
authors.initials: SY
authors.lastname: Kim
authors.forename: Jong-Wook
authors.initials: JW
authors.lastname: Kim
authors.forename: Hye-Kyung
authors.initials: HK
authors.lastname: Park
mesh_terms: D000328:Adult; D000368:Aged; D001774:Blood Chemical Analysis; D001794:Blood Pressure / Q000187:drug effects / Q000502:physiology; D004039:Diet, Sodium-Restricted / Q000379:methods; D006801:Humans; D006973:Hypertension / Q000178:diet therapy* / Q000209:etiology / Q000517:prevention & control; D008875:Middle Aged; D056910:Republic of Korea; D012982:Sodium, Dietary / Q000009:adverse effects*; D016482:Urinalysis; D055815:Young Adult
chemical_list: D012982:Sodium, Dietary