title: Two contemporary cases of hepatitis associated with Teucrium chamaedrys L. decoction use: case reports and review of literature.
abstract: Teucrium chamaedrys L. is a herbaceous plant common in European woods that has been used for many purposes for centuries. Recently, T. chamaedrys L. has become popular as a slimming decoction without any scientific proof of efficacy notwithstanding its well-known hepatotoxicity. Hydroalcoholic extracts are currently used as flavourings in the preparation of wines, bitters and liqueurs. Teucrin A and teuchamaedryn A are the major toxic components of the diterpenoid fraction of T. chamaedrys L.
authors.affiliation: Center of Integrative Medicine, AOU Careggi, Universitary Medical Hospital, Florence, Italy. firenzuolif@aou-careggi.toscana.it
authors.forename: Luigi
authors.initials: L
authors.lastname: Gori
authors.forename: Paola
authors.initials: P
authors.lastname: Galluzzi
authors.forename: Vittorio
authors.initials: V
authors.lastname: Mascherini
authors.forename: Eugenia
authors.initials: E
authors.lastname: Gallo
authors.forename: Francesco
authors.initials: F
authors.lastname: Lapi
authors.forename: Francesca
authors.initials: F
authors.lastname: Menniti-Ippolito
authors.forename: Roberto
authors.initials: R
authors.lastname: Raschetti
authors.forename: Alessandro
authors.initials: A
authors.lastname: Mugelli
authors.forename: Alfredo
authors.initials: A
authors.lastname: Vannacci
authors.forename: Fabio
authors.initials: F
authors.lastname: Firenzuoli
mesh_terms: D000368:Aged; D056486:Chemical and Drug Induced Liver Injury / Q000175:diagnosis / Q000209:etiology*; D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification; D005260:Female; D006801:Humans; D008111:Liver Function Tests; D008297:Male; D015394:Molecular Structure; D010936:Plant Extracts / Q000009:adverse effects* / Q000737:chemistry / Q000302:isolation & purification; D031367:Teucrium / Q000009:adverse effects* / Q000737:chemistry
chemical_list: D004224:Diterpenes; D010936:Plant Extracts; C040618:teucrium extract