title: Genome-wide association studies in lung disease.
abstract: Genome-wide association studies (GWAS) have provided new insights into the molecular mechanisms of lung function and lung diseases. GWAS, and studies that build upon their findings, will continue to provide evidence aimed at advancing understanding of lung disease. This paper summarises the key features of a GWAS, references some recent findings and discusses how the chest physician can interpret the validity and utility of future GWAS and related studies.
authors.affiliation: Department of Health Sciences, University of Leicester, Leicester LE1 7RH, UK. msa20@le.ac.uk
authors.forename: María
authors.initials: M
authors.lastname: Soler Artigas
authors.forename: Louise V
authors.initials: LV
authors.lastname: Wain
authors.forename: Martin D
authors.initials: MD
authors.lastname: Tobin
mesh_terms: D020022:Genetic Predisposition to Disease; D055106:Genome-Wide Association Study; D006801:Humans; D008171:Lung Diseases / Q000235:genetics*; D008173:Lung Diseases, Obstructive / Q000235:genetics; D020641:Polymorphism, Single Nucleotide