title: Signaling of hypochlorous acid by selective deprotection of dithiane. [corrected].
abstract: The selective signaling of hypochlorous acid by dithiane-protected [corrected] pyrene-aldehyde was investigated. Dithiolane derivative of pyrene-aldehyde was efficiently deprotected by hypochlorous acid to its corresponding aldehyde, which resulted in a prominent UV-vis and turn-on type fluorescence signaling. The signaling was not affected by the presence of other common alkali, alkaline earth metal ions, and anions. Interference from Hg(2+) ions could be successfully circumvented by using Chelex-100 resin. Dithiane [corrected] also provided selectivity toward hypochlorous acid over other commonly used oxidant of hydrogen peroxide.
authors.affiliation: Department of Chemistry, Chung-Ang University, Seoul, 156-756, Korea.
authors.forename: Jiyoung
authors.initials: J
authors.lastname: Hwang
authors.forename: Myung Gil
authors.initials: MG
authors.lastname: Choi
authors.forename: Jihee
authors.initials: J
authors.lastname: Bae
authors.forename: Suk-Kyu
authors.initials: SK
authors.lastname: Chang
mesh_terms: D006863:Hydrogen-Ion Concentration; D006997:Hypochlorous Acid / Q000737:chemistry*; D015394:Molecular Structure; D008063:Thioctic Acid / Q000737:chemistry*
chemical_list: D006997:Hypochlorous Acid; D008063:Thioctic Acid