title: Trichosporon asahii keratitis in a patient with a type I Boston keratoprosthesis and contact lens.
abstract: OBJECTIVE
  The aim of the study was to report a case of Trichosporon asahii in a patient with a type I Boston keratoprosthesis and contact lens with review of the literature.
  
  
  METHODS
  A case report and literature review are provided.
  
  
  RESULTS
  A 70-year-old monocular South Asian man with light perception vision and dense corneal scarring from previously failed amniotic membrane grafting and one failed corneal transplant was evaluated for a keratoprosthesis for visual rehabilitation. Three months after undergoing uneventful implantation of a type I Boston keratoprosthesis and placement of a therapeutic contact lens, he was found on routine follow-up to have a corneal infiltrate that was culture positive for T. asahii. The fungal keratitis was successfully treated with topical amphotericin B and oral ketoconazole.
  
  
  CONCLUSIONS
  Contact lens wear is a known risk factor for fungal keratitis. Trichosporon is an uncommon agent of fungal keratitis. We report the first known case of fungal keratitis caused by T.asahii in a patient with a keratoprosthesis and contact lens.
authors.affiliation: Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA, USA. keat0026@gmail.com
authors.forename: Anne
authors.initials: A
authors.lastname: Keating
authors.forename: Roberto
authors.initials: R
authors.lastname: Pineda
mesh_terms: D000368:Aged; D003261:Contact Lenses / Q000009:adverse effects*; D015821:Eye Infections, Fungal / Q000382:microbiology*; D006801:Humans; D007634:Keratitis / Q000382:microbiology*; D008297:Male; D019736:Prostheses and Implants / Q000009:adverse effects*; D016459:Prosthesis-Related Infections / Q000382:microbiology*; D014250:Trichosporon / Q000302:isolation & purification; D060586:Trichosporonosis / Q000175:diagnosis*