title: Sedentary leisure time behavior, snacking habits and cardiovascular biomarkers: the Inter99 Study.
abstract: OBJECTIVE
  To explore the association between sedentary leisure time behavior (SLTB) and cardiovascular biomarkers, taking into account snacking habits, alcohol intake and physical activity level.
  
  
  METHODS
  Cross-sectional.
  
  
  METHODS
  Study participants were recruited from the 5-year follow-up of a population-based intervention study, The Inter99 Study (1999-2006, Copenhagen, Denmark). A group of 6536 men and women, aged 35-65, was invited to attend a health examination and fill in a self-report questionnaire. Multiple linear regression analysis was applied.
  
  
  RESULTS
  Response rate was 69% (N = 4511), with equal gender distribution and mean age of 52. SLTB (hours per day) was significantly positively associated with triglyceride in men (β = 1.030, [1.013; 1.047]) and women (β = 1.036, [1.022; 1.050]), non-HDL cholesterol in men (β = 0.044, [0.012; 0.076]) and women (β = 0.064, [0.035; 0.094]), waist circumference in men (β = 0.835, [0.517; 1.153]) and women (β = 1.234, [0.087; 1.598]), and with waist/hip ratio (WHR) in men (β = 0.0054, [0.0036; 0.0073]) and women (β = 0.0040, [0.0019; 0.0060]). The associations persisted after adjustment for relevant confounders, except in HDL, where the association became non-significant in men (β = 0.9924, [0.9839; 1.0011]) and women (β = 0.9932, [0.8605; 1.0014]).
  
  
  CONCLUSIONS
  SLTB appears to be an independent CVD risk factor, regardless of snacking habits and physical activity.
authors.affiliation: Research Centre for Prevention and Health, Glostrup University Hospital, Glostrup, Denmark. gfrydenlund@hotmail.com
authors.forename: Gitte
authors.initials: G
authors.lastname: Frydenlund
authors.forename: Torben
authors.initials: T
authors.lastname: Jørgensen
authors.forename: Ulla
authors.initials: U
authors.lastname: Toft
authors.forename: Charlotta
authors.initials: C
authors.lastname: Pisinger
authors.forename: Mette
authors.initials: M
authors.lastname: Aadahl
mesh_terms: D000328:Adult; D000368:Aged; D015415:Biomarkers / Q000097:blood*; D015992:Body Mass Index; D002318:Cardiovascular Diseases / Q000097:blood / Q000453:epidemiology / Q000523:psychology*; D003718:Denmark / Q000453:epidemiology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007899:Leisure Activities / Q000523:psychology*; D008019:Life Style; D008297:Male; D008875:Middle Aged; D009043:Motor Activity; D011159:Population Surveillance; D015995:Prevalence; D011379:Prognosis; D012189:Retrospective Studies; D012307:Risk Factors; D062410:Snacks / Q000523:psychology*; D013997:Time Factors
chemical_list: D015415:Biomarkers