title: Mg- and Zn-modified calcium phosphates prepared by biomimetic precipitation and subsequent treatment at high temperature.
abstract: Powders of magnesium-modified as well as zinc-modified calcium phosphates (Me-β-TCP and HA) with a (Ca(2+)+Mg(2+)+Zn(2+)+Na(+)+K(+))/P ratio of 1.3-1.4 and various Me(2+)/(Me(2+)+Ca(2+)) ratios (from 0.005 to 0.16) were prepared in biomimetic electrolyte systems at pH 8, mother liquid maturation and further syntering at 600-1000°C. Some differences in zinc and magnesium modifications have been prognosed on the basis of thermodynamic modeling of the studied systems and explained by the Mg(2+) and Zn(2+) ion chemical behaviour. The temperature as well as the degree of Zn(2+) and Mg(2+) ions substitutions were found to stabilize the β-TCP structure and this effect was more prononced for zinc. Thus, zinc-modified β-TCP powders consisting of idiomorphic crystals were obtained through sintering of Zn(2+) ion substituted calcium phosphates precursors at 800-1000°C. The Mg(2+) ion substitution leads to obtaining magnesium-modified β-TCP with spherical grains.
authors.affiliation: Institute of General and Inorganic Chemistry, Bulgarian Academy of Sciences, Acad. G. Bontchev Str., Bl.11, 1113, Sofia, Bulgaria. didiarab@svr.igic.bas.bg
authors.forename: D
authors.initials: D
authors.lastname: Rabadjieva
authors.forename: S
authors.initials: S
authors.lastname: Tepavitcharova
authors.forename: R
authors.initials: R
authors.lastname: Gergulova
authors.forename: K
authors.initials: K
authors.lastname: Sezanova
authors.forename: R
authors.initials: R
authors.lastname: Titorenkova
authors.forename: O
authors.initials: O
authors.lastname: Petrov
authors.forename: E
authors.initials: E
authors.lastname: Dyulgerova
mesh_terms: D001672:Biocompatible Materials / Q000737:chemistry; D001826:Body Fluids / Q000737:chemistry; D002130:Calcium Phosphates / Q000737:chemistry*; D011232:Chemical Precipitation; D006358:Hot Temperature; D006801:Humans; D008274:Magnesium / Q000737:chemistry*; D008855:Microscopy, Electron, Scanning; D010949:Plasma / Q000737:chemistry; D015032:Zinc / Q000737:chemistry*
chemical_list: D001672:Biocompatible Materials; D002130:Calcium Phosphates; D008274:Magnesium; D015032:Zinc