title: [Common carotid arterial diameter and coronary artery disease].
abstract: The clinical significance of the diameter of common carotid artery (CCA) measured ultrasonographically has not been sufficiently established. The object of this cross-sectional study was to investigate the relationship of the ultrasonic CCA diameter with coronary artery disease (CAD). In the male patients (n=169, mean age: 61 years) who had no apparent carotid arterial stenosis and cerebrovascular disease, a history of CAD, current smoking, body mass index, blood pressure, hemoglobin A1c, serum low-density-lipoprotein cholesterol, estimated glomerular filtration rate and ultrasonic measures of CCA diameter were analyzed. A total of 25 patients had a history of CAD (15%). The CCA diameters of patients with CAD were significantly higher than those of patients without CAD (7.9 +/- 1.0 mm and 7.4 +/- 0.9 mm; p = 0.01). Receiver operating characteristic curve of boundary value of CCA diameter revealed an area under the curve to identify the patients with CAD (0.63, p = 0.04). When the cut off value was considered 8.5 mm, the odds ratio was 4.50 (95% confidence interval = 1.71-11.84, p < 0.01), and the ratio were not largely altered in multivariate logistic regression analyses. The CCA diameter may therefore serve as a useful predictive marker for CAD in men.
authors.affiliation: Department of Clinical Laboratory Medicine, Jichi Medical University, Shimotsuke 329-0498, Japan.
authors.forename: Michiaki
authors.initials: M
authors.lastname: Miyamoto
authors.forename: Kazuhiko
authors.initials: K
authors.lastname: Kotani
authors.forename: Kei
authors.initials: K
authors.lastname: Konno
authors.forename: Toshiyuki
authors.initials: T
authors.lastname: Yamada
authors.forename: Shun
authors.initials: S
authors.lastname: Ishibashi
authors.forename: Nobuyuki
authors.initials: N
authors.lastname: Taniguchi
mesh_terms: D000368:Aged; D015415:Biomarkers; D017536:Carotid Artery, Common / Q000000981:diagnostic imaging* / Q000473:pathology*; D003324:Coronary Artery Disease / Q000175:diagnosis*; D003430:Cross-Sectional Studies; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D011237:Predictive Value of Tests; D012372:ROC Curve; D014463:Ultrasonography
chemical_list: D015415:Biomarkers