title: Renal transplantation in patients with atypical haemolytic uraemic syndrome: a tailor made approach is necessary.
abstract: A 33-year-old woman with a history of chronic transplant dysfunction because of repeated bouts of haemolytic uraemic syndrome (HUS) was considered for a second transplant. Extensive genetic investigation of the complement system was executed to rule out known mutations prone to development of HUS. This case illustrates the importance of genetic screening in patients with recurrent HUS.
authors.affiliation: Department of Nephrology, Academic Medical Centre, Groningen, the Netherlands. jacobien1@hotmail.com
authors.forename: J
authors.initials: J
authors.lastname: van der Wijk
authors.forename: W M
authors.initials: WM
authors.lastname: Smid
authors.forename: M A
authors.initials: MA
authors.lastname: Seelen
authors.forename: N C
authors.initials: NC
authors.lastname: van de Kar
authors.forename: J J G
authors.initials: JJ
authors.lastname: Offerman
authors.forename: W J
authors.initials: WJ
authors.lastname: van Son
mesh_terms: D000328:Adult; D065766:Atypical Hemolytic Uremic Syndrome; D017242:Complement Factor H / Q000235:genetics / Q000276:immunology*; D018450:Disease Progression; D005260:Female; D006463:Hemolytic-Uremic Syndrome / Q000235:genetics / Q000276:immunology / Q000517:prevention & control / Q000601:surgery; D006801:Humans; D007165:Immunosuppression Therapy / Q000379:methods; D007166:Immunosuppressive Agents / Q000008:administration & dosage; D007676:Kidney Failure, Chronic / Q000209:etiology / Q000601:surgery*; D016030:Kidney Transplantation / Q000009:adverse effects / Q000276:immunology* / Q000592:standards; D019520:Living Donors; D010951:Plasma Exchange / Q000379:methods; D012086:Reoperation / Q000592:standards; D016559:Tacrolimus / Q000008:administration & dosage; D061349:Unrelated Donors
chemical_list: D007166:Immunosuppressive Agents; D017242:Complement Factor H; D016559:Tacrolimus