title: Benign notochordal lesions of the axial skeleton: a review and current appraisal.
abstract: At the 1996 meeting of the International Skeletal Society, an idea was put forth that there existed symptomatic lesions of the axial skeleton, morphologically different from chordoma, that were consistent with benign notochordal remnants (rests). A review of the embryological basis for this concept is made, along with an analysis of these lesions, termed giant notochordal rests or benign notochordal cell tumors, that have been reported in the intervening 15 years, with a commentary on their relationship, if any, to chordoma.
authors.affiliation: Division of Surgical Pathology, Washington University School of Medicine, St. Louis, MO, USA. mkyriakos@path.wustl.edu
authors.forename: Michael
authors.initials: M
authors.lastname: Kyriakos
mesh_terms: D002817:Chordoma / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D009672:Notochord / Q000473:pathology*; D013125:Spinal Neoplasms / Q000473:pathology*