title: [Functional activity of peritoneal macrophages in acute destructive pancreatitis: evaluation, implication].
abstract: According to the etiology of acute pancreatitis, the authors identified the most common phenotypes of superficial antigens of peritoneal macrophages: CD14(+) CD25(-)CD64(-)HLA-DR(-) in acute biliary pancreatitis, CD14(+) CD25(+)CD64(+)HLA-DR(+) in nonbiliary pancreatitis; moreover, all the patients were found to have increased expression of early (CD25+) and late (HLA-DR+) markers of cell activation. A comparative study was conducted and the most informative tools to evaluate the adhesive, cytokine-producing, phagocytic, and oxygen-dependent activities of peritoneal macrophages were recognized.
authors.forename: I Iu
authors.initials: IIu
authors.lastname: Ukhanova
authors.forename: A V
authors.initials: AV
authors.lastname: Karaulov
authors.forename: A I
authors.initials: AI
authors.lastname: Konoplia
authors.forename: A L
authors.initials: AL
authors.lastname: Loktionov
authors.forename: O A
authors.initials: OA
authors.lastname: Suniaĭkina
mesh_terms: D000328:Adult; D002448:Cell Adhesion / Q000276:immunology; D002469:Cell Separation; D016207:Cytokines / Q000276:immunology; D003601:Cytotoxicity Tests, Immunologic; D006684:HLA-DR Antigens / Q000032:analysis; D006801:Humans; D007159:Immunologic Tests / Q000379:methods*; D053645:Interleukin-2 Receptor alpha Subunit / Q000032:analysis; D018950:Lipopolysaccharide Receptors / Q000032:analysis; D008262:Macrophage Activation; D017737:Macrophages, Peritoneal / Q000145:classification / Q000276:immunology*; D019283:Pancreatitis, Acute Necrotizing / Q000276:immunology*; D010587:Phagocytosis; D017452:Receptors, IgG / Q000032:analysis
chemical_list: D016207:Cytokines; D006684:HLA-DR Antigens; D053645:Interleukin-2 Receptor alpha Subunit; D018950:Lipopolysaccharide Receptors; D017452:Receptors, IgG