title: Histological diagnosis determines complications of percutaneous renal biopsy: a single-center experience in 353 patients.
abstract: BACKGROUND
  We studied the connection between complication occurrence related to renal biopsies and histological diagnoses of the biopsy specimen. We also analyzed the distribution of diagnoses in our population.
  
  
  METHODS
  We retrospectively studied 353 patients undergoing renal biopsy at the same center. Biopsies were performed after marking the site of puncture by ultrasound imaging. Connection of complications with diagnoses and clinical parameters was evaluated.
  
  
  RESULTS
  Complication rate was 44.5% in our study. There was a significantly lower rate of complications in patients with diabetic nephropathy (likelihood ratio, LR = 0.44) or acute tubular necrosis (LR = 0.38), while patients with thin basement membrane syndrome had a more than 6-fold higher risk for development of intrarenal hemorrhage than others. Patients with vasculitis (LR = 2.88) and acute interstitial nephritis (LR = 3.18) have a more than doubled risk for arteriovenous shunts, while in patients with severe arteriosclerosis the prevalence of this complication was lower (LR = 0.46). Arteriovenous shunts developed also at a significantly higher rate in patients with rapidly progressive glomerulonephritis.
  
  
  CONCLUSIONS
  Patients with thin basement membrane syndrome, vasculitis, rapidly progressive glomerulonephritis or acute interstitial nephritis should be observed more carefully after renal biopsy due to the significantly higher risk for certain complications.
authors.affiliation: Second Department of Medicine and Nephrological Center, University of Pécs, Pécs, Hungary.
authors.forename: Viktória
authors.initials: V
authors.lastname: Fisi
authors.forename: István
authors.initials: I
authors.lastname: Mazák
authors.forename: Péter
authors.initials: P
authors.lastname: Degrell
authors.forename: Richárd
authors.initials: R
authors.lastname: Halmai
authors.forename: Gergo A
authors.initials: GA
authors.lastname: Molnár
authors.forename: Eszter
authors.initials: E
authors.lastname: Fehér
authors.forename: Kinga
authors.initials: K
authors.lastname: Németh
authors.forename: István
authors.initials: I
authors.lastname: Pintér
authors.forename: Tibor
authors.initials: T
authors.lastname: Kovács
authors.forename: István
authors.initials: I
authors.lastname: Wittmann
mesh_terms: D000328:Adult; D001706:Biopsy / Q000009:adverse effects; D005260:Female; D006801:Humans; D007668:Kidney / Q000473:pathology*; D007674:Kidney Diseases / Q000175:diagnosis* / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies