title: Clinical manifestations and pathogenesis of tonsillar focal diseases: IgA nephropathy and palmoplantar pustulosis.
abstract: Tonsillar focal disease is defined as clinical disorders in the distant organ from the tonsil that are caused by the tonsils without any symptoms of the tonsil itself. Palmoplantar pustulosis and IgA nephropathy are known typical tonsillar focal diseases. In this paper, the clinical outcome of tonsillectomy and the etiological evidence of related diseases are reviewed.
authors.affiliation: Department of Otolaryngology- Head and Neck Surgery, Asahikawa Medical University, Asahikawa, Hokkaido, Japan. hyasu@asahikawa-med.ac.jp
authors.forename: Yasuaki
authors.initials: Y
authors.lastname: Harabuchi
mesh_terms: D060908:CTLA-4 Antigen / Q000096:biosynthesis / Q000235:genetics; D005922:Glomerulonephritis, IGA / Q000209:etiology* / Q000276:immunology / Q000628:therapy; D005938:Glucocorticoids / Q000627:therapeutic use*; D006801:Humans; D007111:Immunity, Cellular; D014066:Palatine Tonsil / Q000276:immunology / Q000473:pathology*; D011565:Psoriasis / Q000209:etiology* / Q000276:immunology / Q000628:therapy; D012333:RNA, Messenger / Q000235:genetics; D012307:Risk Factors; D051906:Smad7 Protein / Q000096:biosynthesis / Q000235:genetics; D013601:T-Lymphocytes / Q000276:immunology; D014068:Tonsillectomy; D014069:Tonsillitis / Q000150:complications* / Q000235:genetics / Q000601:surgery
chemical_list: D060908:CTLA-4 Antigen; D005938:Glucocorticoids; D012333:RNA, Messenger; D051906:Smad7 Protein