title: A new vampire saga: the molecular mechanism of T cell trogocytosis.
abstract: In the current issue of Immunity, Martínez-Martín et al. (2011) describe the central supramolecular activation cluster (cSMAC) as a site of clathrin-independent T cell receptor (TCR) internalization and trogocytosis. Further, they identify small Rho GTPases TC21 and RhoG as key mediators of these processes.
authors.affiliation: Department of Molecular Immunology, Faculty of Biology, BIOSS Centre for Biological Signalling Studies, Center for Chronic Immunodeficiency (CCI) and Max-Planck-Institute for Immunbiology and Epigenetics, Stübeweg 51, 79108 Freiburg, Germany.
authors.forename: Elaine Pashupati
authors.initials: EP
authors.lastname: Dopfer
authors.forename: Susana
authors.initials: S
authors.lastname: Minguet
authors.forename: Wolfgang W A
authors.initials: WW
authors.lastname: Schamel