title: Admission hyperglycemia and TIMI frame count in primary percutaneous coronary intervention.
abstract: We evaluated the relationship between admission blood glucose levels and estimated coronary flow by the thrombolysis in myocardial infarction (TIMI) frame count (TFC) method in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (pPCI). The TFC of 121 consecutive patients with STEMI were evaluated after pPCI. Patients with admission glucose levels > 198 mg/dL (11 mmol/L) were defined as hyperglycemic. Hyperglycemia was observed in 36 (29.8%) patients. The TFC was significantly higher in patients with hyperglycemia (70.75 [10-96] vs 56.87 [8-100], P = .04). No-reflow frequency was higher in the hyperglycemia group (44.4% vs 23.5%, P = .02). In multivariate linear regression analysis admission glucose was an independent predictor of high TFC (B = 0.21, P = .02). Our findings suggest that admission blood glucose is a predictor of TFC which reflects coronary blood flow.
authors.affiliation: Department of Cardiology, Istanbul University Institute of Cardiology, Istanbul, Turkey.
authors.forename: Ahmet
authors.initials: A
authors.lastname: Yildiz
authors.forename: Alev
authors.initials: A
authors.lastname: Arat-Ozkan
authors.forename: Cuneyt
authors.initials: C
authors.lastname: Kocas
authors.forename: Okay
authors.initials: O
authors.lastname: Abaci
authors.forename: Ugur
authors.initials: U
authors.lastname: Coskun
authors.forename: Cem
authors.initials: C
authors.lastname: Bostan
authors.forename: Ayhan
authors.initials: A
authors.lastname: Olcay
authors.forename: Faruk
authors.initials: F
authors.lastname: Akturk
authors.forename: Baris
authors.initials: B
authors.lastname: Okcun
authors.forename: Murat
authors.initials: M
authors.lastname: Ersanli
authors.forename: Tevfik
authors.initials: T
authors.lastname: Gurmen
mesh_terms: D000368:Aged; D015906:Angioplasty, Balloon, Coronary / Q000009:adverse effects; D001786:Blood Glucose / Q000032:analysis*; D016009:Chi-Square Distribution; D017023:Coronary Angiography; D003326:Coronary Circulation; D005260:Female; D006801:Humans; D006943:Hyperglycemia / Q000097:blood / Q000175:diagnosis*; D016014:Linear Models; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D009203:Myocardial Infarction / Q000150:complications / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000628:therapy*; D054318:No-Reflow Phenomenon / Q000097:blood / Q000209:etiology / Q000503:physiopathology; D010343:Patient Admission; D011237:Predictive Value of Tests; D018570:Risk Assessment; D012307:Risk Factors; D016896:Treatment Outcome; D014421:Turkey
chemical_list: D001786:Blood Glucose