title: Oxo-tethered ruthenium(II) complex as a bifunctional catalyst for asymmetric transfer hydrogenation and H2 hydrogenation.
abstract: Newly developed oxo-tethered Ru amido complexes (R,R)-1 and their HCl adducts (R,R)-2 exhibited excellent catalytic performance for both asymmetric transfer hydrogenation and the hydrogenation of ketonic substrates under neutral conditions without any cocatalysts to give chiral secondary alcohols with high levels of enantioselectivity.
authors.affiliation: Corporate Research & Development Division, Takasago International Corporation, Hiratsuka City, Kanagawa, Japan.
authors.forename: Taichiro
authors.initials: T
authors.lastname: Touge
authors.forename: Tomohiko
authors.initials: T
authors.lastname: Hakamata
authors.forename: Hideki
authors.initials: H
authors.lastname: Nara
authors.forename: Tohru
authors.initials: T
authors.lastname: Kobayashi
authors.forename: Noboru
authors.initials: N
authors.lastname: Sayo
authors.forename: Takao
authors.initials: T
authors.lastname: Saito
authors.forename: Yoshihito
authors.initials: Y
authors.lastname: Kayaki
authors.forename: Takao
authors.initials: T
authors.lastname: Ikariya
mesh_terms: D000438:Alcohols / Q000138:chemical synthesis* / Q000737:chemistry; D000577:Amides / Q000737:chemistry*; D002384:Catalysis; D006859:Hydrogen / Q000737:chemistry*; D006865:Hydrogenation; D007659:Ketones / Q000737:chemistry; D007783:Lactones / Q000737:chemistry; D008958:Models, Molecular; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D012428:Ruthenium / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000438:Alcohols; D000577:Amides; D007659:Ketones; D007783:Lactones; D009942:Organometallic Compounds; D012428:Ruthenium; D006859:Hydrogen