title: Primary sternal osteomyelitis due to Peptostreptococcus anaerobius.
abstract: Primary sternal osteomyelitis (PSO) is a rare syndrome. In adults, it usually occurs with underlying predisposing factors, such as immunodeficiency, or intravenous (IV) drug abuse. The infecting organism in these patients is usually Staphylococcus aureus or Pseudomonas aeruginosa. Peptostreptococcus species are Gram-positive anaerobic cocci and are part of the normal flora of human mucocutaneous surfaces. Peptostreptococcus infection can occur in all body sites, including the central nervous system, head, neck, chest, abdomen, pelvis, skin, bone, joint, and soft tissue. Here, we report on a 32-year-old previously healthy Chinese man who was diagnosed with PSO and P. anaerobius was yielded in the bacterial culture. He was treated empirically with antibiotics, but these failed. After additional limited surgical intervention with debridement, the PSO was cured.
authors.affiliation: Department of Emergency Medicine, National Defense Medical Center, Taipei, Taiwan.
authors.forename: Y-L
authors.initials: YL
authors.lastname: Chen
authors.forename: S-H
authors.initials: SH
authors.lastname: Tsai
authors.forename: K-C
authors.initials: KC
authors.lastname: Hsu
authors.forename: C-S
authors.initials: CS
authors.lastname: Chen
authors.forename: C-W
authors.initials: CW
authors.lastname: Hsu
mesh_terms: D000328:Adult; D000658:Amoxicillin / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D044466:Asian People; D019818:Clavulanic Acid / Q000627:therapeutic use; D003646:Debridement / Q000379:methods*; D016908:Gram-Positive Bacterial Infections / Q000382:microbiology* / Q000628:therapy; D006801:Humans; D008297:Male; D010019:Osteomyelitis / Q000382:microbiology* / Q000628:therapy; D010068:Oxacillin / Q000627:therapeutic use; D010462:Peptostreptococcus / Q000302:isolation & purification*; D013249:Sternum; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D019818:Clavulanic Acid; D000658:Amoxicillin; D010068:Oxacillin