title: LAK cell therapy of AML: not to be lost in translation.
abstract: Expanding highly cytotoxic lymphokine activated natural killer cells and cytokine induced killer T cells by Good Manufacturing Practice-quality cultures is an important step toward effective use of those killer cells to treat acute myeloid leukemia patients receiving stem cell transplantation. Elucidating how those killer cells recognize leukemia stem cells will be the next challenge.
authors.affiliation: Terry Fox Laboratory, BC Cancer Agency, Vancouver, Canada. ftakei@bccrc.ca
authors.forename: Fumio
authors.initials: F
authors.lastname: Takei
mesh_terms: D018929:Cell Culture Techniques / Q000379:methods; D064987:Cell- and Tissue-Based Therapy / Q000379:methods*; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D007167:Immunotherapy / Q000379:methods; D015979:Killer Cells, Lymphokine-Activated / Q000276:immunology* / Q000637:transplantation*; D015470:Leukemia, Myeloid, Acute / Q000473:pathology / Q000628:therapy*; D014411:Neoplastic Stem Cells / Q000276:immunology