title: Proteasome modulator 9 and carpal tunnel syndrome.
abstract: Proteasome modulator 9 (PSMD9) is linked to type 2 diabetes (T2D). The author studied whether PSMD9 IVS3 + nt460 A > G, IVS3 + nt437 T > C and E197 are linked to carpal tunnel syndrome in T2D Italian families. Non-parametric linkage, linkage disequilibrium-based and independent SNPs-based linkage analyses were performed. The PSMD9 SNPs show linkage to carpal tunnel syndrome.
authors.affiliation: Laboratory of Molecular Genetics of Complex and Monogenic Disorders, Department of Medicine and Cellular & Molecular Physiology and Biostatistics, Penn State University and MS Hershey Medical Center, Hershey, PA 17033, United States. claudia.gragnoli@gmail.com
authors.forename: Claudia
authors.initials: C
authors.lastname: Gragnoli
mesh_terms: D002349:Carpal Tunnel Syndrome / Q000453:epidemiology / Q000235:genetics*; D048909:Diabetes Complications / Q000453:epidemiology / Q000235:genetics*; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000453:epidemiology / Q000235:genetics*; D005787:Gene Frequency; D020022:Genetic Predisposition to Disease; D006801:Humans; D007558:Italy / Q000453:epidemiology; D015810:Linkage Disequilibrium; D008126:Lod Score; D010641:Phenotype; D020641:Polymorphism, Single Nucleotide; D015995:Prevalence; D046988:Proteasome Endopeptidase Complex / Q000235:genetics*; D018570:Risk Assessment; D012307:Risk Factors
chemical_list: C114476:PSMD9 protein, human; D046988:Proteasome Endopeptidase Complex