title: cis-Glyco-fused benzopyran compounds as new amyloid-β peptide ligands.
abstract: A small library of glyco-fused benzopyran compounds has been synthesised. Their interaction features with Aβ peptides have been characterised by using STD-NMR and trNOESY experiments. The conformational analysis of the compounds has also been carried out through molecular mechanics (MM) and molecular dynamics (MD) simulations.
authors.affiliation: Dept. of Biotechnology and Biosciences, University of Milano-Bicocca, P.zza della Scienza 2, 20126, Milan, Italy.
authors.forename: Cristina
authors.initials: C
authors.lastname: Airoldi
authors.forename: Francisco
authors.initials: F
authors.lastname: Cardona
authors.forename: Erika
authors.initials: E
authors.lastname: Sironi
authors.forename: Laura
authors.initials: L
authors.lastname: Colombo
authors.forename: Mario
authors.initials: M
authors.lastname: Salmona
authors.forename: Artur
authors.initials: A
authors.lastname: Silva
authors.forename: Francesco
authors.initials: F
authors.lastname: Nicotra
authors.forename: Barbara
authors.initials: B
authors.lastname: La Ferla
mesh_terms: D016229:Amyloid beta-Peptides / Q000378:metabolism*; D001578:Benzopyrans / Q000737:chemistry* / Q000378:metabolism*; D008024:Ligands; D011485:Protein Binding; D013237:Stereoisomerism
chemical_list: D016229:Amyloid beta-Peptides; D001578:Benzopyrans; D008024:Ligands