title: Steric Crowding Makes Challenging C(sp3)-F Reductive Eliminations Feasible.
abstract: A high-yielding fluorination of (triphos)Pt-R(+) has been achieved using an array of F(+) sources, with XeF(2) yielding R-F in minutes. The C-F coupling proved to be a stereoretentive process that proceeds via a concerted reductive elimination from a putative dicationic Pt(IV) center. The larger the steric congestion of the (triphos)Pt-C(sp3) (+) complexes, the more efficient the fluorination, seemingly a result of sterically accelerated C-F reductive elimination along with simultaneous deceleration of its competing processes (β-H elimination).
authors.affiliation: Caudill Laboratories, Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-3290, USA.
authors.forename: Shu-Bin
authors.initials: SB
authors.lastname: Zhao
authors.forename: Jennifer J
authors.initials: JJ
authors.lastname: Becker
authors.forename: Michel R
authors.initials: MR
authors.lastname: Gagné