title: Voluven, a new colloid solution.
abstract: Hydroxyethyl starch (HES) 130/0.4 (Voluven, Fresenius/Hospira, Germany) is indicated for the treatment and prophylaxis of hypovolemia. As the Voluven molecule is smaller than those of other available hydroxyethyl starch products, it is associated with less plasma accumulation and can be safely used in patients with renal impairment. Previous studies have demonstrated that Voluven has comparable effects on volume expansion and hemodynamics as other available HES products. Voluven is also associated with fewer effects on coagulation and may be an acceptable alternative to albumin for volume expansion in situations in which other starches are contraindicated secondary to risk of coagulopathy.
authors.affiliation: Department of Cardiothoracic and Vascular Anesthesia, San Raffaele Hospital, "Vita e Salute" University, Milan, Italy.
authors.forename: Anna
authors.initials: A
authors.lastname: Mizzi
authors.forename: Thanh
authors.initials: T
authors.lastname: Tran
authors.forename: Rachel
authors.initials: R
authors.lastname: Karlnoski
authors.forename: Ashley
authors.initials: A
authors.lastname: Anderson
authors.forename: Devanand
authors.initials: D
authors.lastname: Mangar
authors.forename: Enrico M
authors.initials: EM
authors.lastname: Camporesi
mesh_terms: D016063:Blood Loss, Surgical; D003102:Colloids / Q000627:therapeutic use; D000077324:Crystalloid Solutions; D005440:Fluid Therapy; D006801:Humans; D006895:Hydroxyethyl Starch Derivatives / Q000627:therapeutic use; D020896:Hypovolemia / Q000188:drug therapy; D007552:Isotonic Solutions / Q000627:therapeutic use; D010952:Plasma Substitutes; D012709:Serum Albumin / Q000627:therapeutic use
chemical_list: D003102:Colloids; D000077324:Crystalloid Solutions; C485123:HES 130-0.4; D006895:Hydroxyethyl Starch Derivatives; D007552:Isotonic Solutions; D010952:Plasma Substitutes; D012709:Serum Albumin