title: [Saturation of the Polish mitochondrial DNA database].
abstract: The main objective of the study was a statistical evaluation of Polish mitochondrial DNA database, consisting of 1253 maternally unrelated individuals from seven different regions of Poland. Four relevant parameters were examined: haplotype diversity, nucleotide diversity, number of polymorphic positions and number of haplotypes, including HVS I and HVS II mtDNA regions. The results show that while haplotype and nucleotide diversities have already reached saturation level, the number of haplotypes and polymorphic positions rises continuously inside the database. These results indicate a need for a substantial increase in the number of haplotypes in Polish mitochondrial DNA database.
authors.affiliation: Z Zakładu Genetyki Molekularnej i Sadowej, Katedry Medycyny Sadowej Uniwersytetu Mikołaja Kopernika w Toruniu, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy.
authors.forename: Patrycja
authors.initials: P
authors.lastname: Daca
authors.forename: Marta
authors.initials: M
authors.lastname: Mielnik-Sikorska
authors.forename: Jarosław
authors.initials: J
authors.lastname: Bednarek
authors.forename: Tomasz
authors.initials: T
authors.lastname: Grzybowski
mesh_terms: D022801:Complementarity Determining Regions; D016172:DNA Fingerprinting / Q000379:methods; D004272:DNA, Mitochondrial / Q000235:genetics*; D019992:Databases as Topic; D014644:Genetic Variation; D005828:Genetics, Population; D006239:Haplotypes; D006801:Humans; D011044:Poland; D011110:Polymorphism, Genetic; D018401:Sample Size; D044465:White People / Q000235:genetics*
chemical_list: D022801:Complementarity Determining Regions; D004272:DNA, Mitochondrial