title: The central nervous system solitary fibrous tumor: a review of clinical, imaging and pathologic findings among all reported cases from 1996 to 2010.
abstract: OBJECTIVE
  Central nervous system (CNS) solitary fibrous tumor (SFT) is a rare lesion first identified as a unique entity in 1996. We describe two cases treated at the University of Florida followed by a review of all reported cases of CNS SFT between 1996 and 2010.
  
  
  METHODS
  A review of the literature was performed to identify all reported cases of CNS SFT.
  
  
  RESULTS
  189 cases (including the two presented herein) were discovered, of which 46 were spinal and 143 were intracranial. Demographic, imaging, and pathologic findings are presented. Roughly 6% of reported lesions are malignant. Subtotal resection (STR) was associated with a 16-fold increased odds of recurrence (OR 15.9, 95% CI 5.5-46.1), although mean follow-up was shorter in those cases of GTR without recurrence.
  
  
  CONCLUSIONS
  CNS SFT is a rare lesion. Six percent of lesions are malignant. GTR is superior to STR although the degree of superiority is not clear.
authors.affiliation: Department of Neurosurgery, University of Florida College of Medicine, Gainesville, FL, USA. kyle.fargen@neurosurgery.ufl.edu
authors.forename: Kyle M
authors.initials: KM
authors.lastname: Fargen
authors.forename: Katherine J
authors.initials: KJ
authors.lastname: Opalach
authors.forename: Dara
authors.initials: D
authors.lastname: Wakefield
authors.forename: R Patrick
authors.initials: RP
authors.lastname: Jacob
authors.forename: Anthony T
authors.initials: AT
authors.lastname: Yachnis
authors.forename: J Richard
authors.initials: JR
authors.lastname: Lister
mesh_terms: D000328:Adult; D000367:Age Factors; D001932:Brain Neoplasms / Q000453:epidemiology / Q000473:pathology / Q000601:surgery; D016543:Central Nervous System Neoplasms / Q000453:epidemiology / Q000473:pathology* / Q000601:surgery; D002533:Cerebral Angiography; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D019635:Neurosurgical Procedures; D011782:Quadriplegia / Q000209:etiology; D054364:Solitary Fibrous Tumors / Q000453:epidemiology / Q000473:pathology* / Q000601:surgery; D013120:Spinal Cord Neoplasms / Q000453:epidemiology / Q000473:pathology / Q000601:surgery; D016896:Treatment Outcome