title: Factors related to an early restoration of exercise capacity after major lung resection.
abstract: OBJECTIVE
  We attempted to identify the factors related to an early restoration of the exercise capacity after lung resection.
  
  
  METHODS
  Major lung resection was performed in 164 patients. Exercise testing and spirometry were performed before surgery, and 2 weeks and 1 month afterward. During exercise, the maximum oxygen uptake per minute per m(2) of body surface area (VO(2)max/m(2)) was measured. The percent change of VO(2)max/m(2) at 2 weeks and 1 month after surgery was calculated by setting the preoperative VO(2)max/m(2) value as 100%. Patients were then assigned to the early restoration group or late restoration group according to their VO(2)max/m(2) measured 2 weeks after surgery. Preoperative cardiopulmonary function, as well as various preoperative and intraoperative factors were compared between the two groups.
  
  
  RESULTS
  At 2 weeks after surgery, the mean VO(2)max/m(2) was 80.9% compared with that before surgery, and was 88.1% at 1 month. A multivariate analysis showed that the surgical method used (thoracotomy and mediastinal lymph node dissection) had a significant effect on the postoperative restoration of the VO(2)max/m(2).
  
  
  CONCLUSIONS
  An early restoration of exercise capacity after lung resection is possible in patients without mediastinal lymph node dissection and in those who have a small thoracotomy wound.
authors.affiliation: Department of Surgery, National Hospital Organization Omuta National Hospital, 1044-1 Tachibana, Ohmuta, Fukuoka, 837-0911, Japan.
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Nagamatsu
authors.forename: Yasunori
authors.initials: Y
authors.lastname: Iwasaki
authors.forename: Ryozo
authors.initials: R
authors.lastname: Hayashida
authors.forename: Masaki
authors.initials: M
authors.lastname: Kashihara
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Nishi
authors.forename: Koichi
authors.initials: K
authors.lastname: Yoshiyama
authors.forename: Hideaki
authors.initials: H
authors.lastname: Yamana
authors.forename: Kazuo
authors.initials: K
authors.lastname: Shirouzu
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005080:Exercise Test; D017079:Exercise Tolerance; D005260:Female; D006801:Humans; D016015:Logistic Models; D008175:Lung Neoplasms / Q000601:surgery*; D008197:Lymph Node Excision; D008297:Male; D008482:Mediastinum; D008875:Middle Aged; D015999:Multivariate Analysis; D010101:Oxygen Consumption; D011013:Pneumonectomy / Q000379:methods / Q000534:rehabilitation*; D020127:Recovery of Function / Q000502:physiology*; D012189:Retrospective Studies; D013147:Spirometry; D013908:Thoracotomy