title: Extrapulmonary small cell carcinoma: a pictorial review.
abstract: OBJECTIVE
  Extrapulmonary small cell carcinoma (EPSCC) is a rare, aggressive neoplasm arising from virtually any organ. Numerous oncologic studies have addressed prognostic indicators and survival rates in EPSCC, however relatively little has been published regarding the imaging features and metastatic patterns of these uncommon tumors. This article provides a pictorial review of EPSCC in multiple organs, emphasizing the imaging appearance at presentation and the radiologic patterns of recurrence/metastasis.
  
  
  CONCLUSIONS
  Although the appearance of EPSCC is often nonspecific, the typical presentation is large aggressive tumors that, similar to small cell carcinoma in the lung, often respond well to local therapy but tend to recur relentlessly at distant sites.
authors.affiliation: Department of Radiology, Dana-Farber Cancer Institute, 44 Binney St, Boston, MA 02115, USA. sahoward@partners.org
authors.forename: Stephanie
authors.initials: S
authors.lastname: Howard
authors.forename: Kevin
authors.initials: K
authors.lastname: O'Regan
authors.forename: Jyothi
authors.initials: J
authors.lastname: Jagannathan
authors.forename: Katherine
authors.initials: K
authors.lastname: Krajewski
authors.forename: Angela
authors.initials: A
authors.lastname: Giardino
authors.forename: Nikhil
authors.initials: N
authors.lastname: Ramaiya
mesh_terms: D018288:Carcinoma, Small Cell / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D003287:Contrast Media; D003952:Diagnostic Imaging; D005260:Female; D005770:Gastrointestinal Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D006801:Humans; D008297:Male; D009362:Neoplasm Metastasis; D009367:Neoplasm Staging; D011379:Prognosis; D011471:Prostatic Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D014571:Urologic Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy
chemical_list: D003287:Contrast Media