title: Design and synthesis of a terbium(III) complex-based luminescence probe for time-gated luminescence detection of mercury(II) ions.
abstract: Time-gated luminescence detection technique using lanthanide complexes as luminescent probes is a useful and highly sensitive method. However, the effective application of this technique is limited by the lack of the target-responsive luminescent lanthanide complexes that can specifically recognize various analytes in aqueous solutions. In this work, a dual-functional ligand that can form a stable complex with Tb(3+) and specifically recognize Hg(2+) ions in aqueous solutions, N,N,N(1),N(1)-{[2,6-bis(3'-aminomethyl-1'-pyrazolyl)-4-[N,N-bis(3″,6″-dithiaoctyl)-aminomethyl]- pyridine]} tetrakis(acetic acid) (BBAPTA), has been designed and synthesized. The luminescence of its Tb(3+) complex is weak, but can be effectively enhanced upon reaction with Hg(2+) ions in aqueous solutions. The luminescence response investigations of BBAPTA-Tb(3+) to various metal ions indicate that the complex has a good luminescence sensing selectivity for Hg(2+) ions, but not for other metal ions. Thus a highly sensitive time-gated luminescence detection method for Hg(2+) ions was developed by using BBAPTA-Tb(3+) as a luminescent probe. The dose-dependent luminescence enhancement of the probe shows a good linearity with a detection limit of 17 nM for Hg(2+) ions. These results demonstrated the efficacy and advantages of the new Tb(3+) complex-based luminescence probe for the sensitive and selective detection of Hg(2+) ions.
authors.affiliation: State Key Laboratory of Fine Chemicals, School of Chemistry, Dalian University of Technology, Dalian, 116024, People's Republic of China.
authors.forename: Guanfeng
authors.initials: G
authors.lastname: Cui
authors.forename: Zhiqiang
authors.initials: Z
authors.lastname: Ye
authors.forename: Run
authors.initials: R
authors.lastname: Zhang
authors.forename: Guilan
authors.initials: G
authors.lastname: Wang
authors.forename: Jingli
authors.initials: J
authors.lastname: Yuan
mesh_terms: D015195:Drug Design; D049408:Luminescent Agents / Q000138:chemical synthesis / Q000737:chemistry; D008163:Luminescent Measurements; D008628:Mercury / Q000032:analysis* / Q000737:chemistry*; D009942:Organometallic Compounds / Q000138:chemical synthesis* / Q000737:chemistry*; D011720:Pyrazoles / Q000138:chemical synthesis / Q000737:chemistry; D013725:Terbium / Q000737:chemistry*; D013997:Time Factors
chemical_list: D049408:Luminescent Agents; D009942:Organometallic Compounds; D011720:Pyrazoles; D013725:Terbium; D008628:Mercury