title: [Primary immune thrombocytopenia in a patient with sarcoidosis].
abstract: Sarcoidosis is a disease with a strongly variable clinical manifestation. It may be associated with various autoimmune diseases but hematological manifestations have rarely been observed. The prevalence of thrombocytopenia in patients with sarcoidosis has been estimated at 2%, about 1% of patients with thrombocytopenia have been diagnosed with sarcoidosis We present a case of sarcoidosis associated with primary immune thrombocytopenia of an abrupt and severe onset. Three potential patomechanisms of thrombocytopenia in sarcoidosis: 1) autoantibody related platelet destruction, 2) bone marrow involvement, and 3) hipersplenism are discussed.
authors.affiliation: Katedra i Klinika Chorób Wewnętrznych, Pneumonologii i Alergologii Warszawskiego Uniwersytetu Medycznego. mdabrowska@mp.pl
authors.forename: Marta
authors.initials: M
authors.lastname: Dąbrowska
authors.forename: Rafał
authors.initials: R
authors.lastname: Krenke
authors.forename: Marta
authors.initials: M
authors.lastname: Maskey-Warzęchowska
authors.forename: Piotr
authors.initials: P
authors.lastname: Boguradzki
authors.forename: Anna
authors.initials: A
authors.lastname: Waszczuk-Gajda
authors.forename: Wiesław Wiktor
authors.initials: WW
authors.lastname: Jędrzejczak
authors.forename: Paweł
authors.initials: P
authors.lastname: Caban
authors.forename: Ryszarda
authors.initials: R
authors.lastname: Chazan
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D011241:Prednisone / Q000627:therapeutic use; D011859:Radiography; D017565:Sarcoidosis, Pulmonary / Q000150:complications* / Q000000981:diagnostic imaging* / Q000188:drug therapy; D013921:Thrombocytopenia / Q000150:complications* / Q000000981:diagnostic imaging* / Q000188:drug therapy; D016896:Treatment Outcome
chemical_list: D016756:Immunoglobulins, Intravenous; D011241:Prednisone