title: Determination of relative binding affinities of labeling molecules with amino acids by using scanning tunneling microscopy.
abstract: The binding behaviour of labeling molecule copper phthalocyanine tetrasulfonate sodium (PcCu(SO(3)Na)(4)) on the assemblies of representative polyamino acids has been studied by using scanning tunneling microscopy (STM). By directly visualizing the adsorption and distribution of the labeling species on the peptide assemblies in STM images, one could obtain relative binding affinities of the labeling molecule with different amino acid residues.
authors.affiliation: National Center for Nanoscience and Technology, Beijing 100190, China.
authors.forename: Chenxuan
authors.initials: C
authors.lastname: Wang
authors.forename: Xiaobo
authors.initials: X
authors.lastname: Mao
authors.forename: Aihua
authors.initials: A
authors.lastname: Yang
authors.forename: Lin
authors.initials: L
authors.lastname: Niu
authors.forename: Shengnan
authors.initials: S
authors.lastname: Wang
authors.forename: Denghua
authors.initials: D
authors.lastname: Li
authors.forename: Yuanyuan
authors.initials: Y
authors.lastname: Guo
authors.forename: Yibing
authors.initials: Y
authors.lastname: Wang
authors.forename: Yanlian
authors.initials: Y
authors.lastname: Yang
authors.forename: Chen
authors.initials: C
authors.lastname: Wang
mesh_terms: D000327:Adsorption; D000595:Amino Acid Sequence; D000596:Amino Acids / Q000737:chemistry*; D003300:Copper / Q000737:chemistry*; D007211:Indoles / Q000737:chemistry; D016252:Microscopy, Scanning Tunneling; D009942:Organometallic Compounds / Q000737:chemistry*; D010455:Peptides / Q000737:chemistry / Q000378:metabolism; D011485:Protein Binding
chemical_list: D000596:Amino Acids; D007211:Indoles; D009942:Organometallic Compounds; D010455:Peptides; C028418:tetrasulfophthalocyanine; D003300:Copper