title: Does massive cerebral venous thrombosis mean poor outcome?
abstract: A 21-year-old woman taking oral contraceptives presented with headaches, nausea, vomiting and somnolence. The next day she had a generalized tonic-clonic seizure after which her neurological condition deteriorated. CT and MRI showed multiple cerebral haemorrhages, while MR venography revealed extensive dural sinus and venous thrombosis involving almost all sinuses, great cerebral vein of Galen and internal cerebral veins. Two weeks after initiation of the anticoagulant treatment the patient recovered completely with complete recanalization of all cerebral sinuses and veins. Although the patient had conditions which were indicative of poor outcome, her neurological deficit improved completely, which correlated with recanalization of the thrombosed vessels.
authors.affiliation: Clinical Centre of Vojvodina, Department of Neurology. petars@eunet.rs
authors.forename: Petar
authors.initials: P
authors.lastname: Slankamenac
authors.forename: Zeljko
authors.initials: Z
authors.lastname: Zivanović
authors.forename: Aleksandar
authors.initials: A
authors.lastname: Jesić
authors.forename: Branka
authors.initials: B
authors.lastname: Vitić
authors.forename: Svetlana
authors.initials: S
authors.lastname: Ruzicka-Kaloci
authors.forename: Ivana
authors.initials: I
authors.lastname: Divjak
authors.forename: Mirjana
authors.initials: M
authors.lastname: Jovicević
authors.forename: Slobodan
authors.initials: S
authors.lastname: Sekulić
mesh_terms: D000925:Anticoagulants / Q000627:therapeutic use; D002550:Cerebral Veins; D003278:Contraceptives, Oral, Hormonal / Q000009:adverse effects; D005260:Female; D006801:Humans; D020767:Intracranial Thrombosis / Q000139:chemically induced / Q000175:diagnosis / Q000188:drug therapy*; D008279:Magnetic Resonance Imaging; D014057:Tomography, X-Ray Computed; D055815:Young Adult
chemical_list: D000925:Anticoagulants; D003278:Contraceptives, Oral, Hormonal