title: [Histogenesis of the liver of Japanese quail embryos developed in the conditions of microgravity].
abstract: The article reports the results of histogenetic studies of the liver extracted from Japanese quail embryos and hatchlings that had passed the embryonic and postnatal development in microgravity. Comparison of the liver from the flight and laboratory embryos showed identity of organogenesis and histogenesis processes in space and on Earth. However, it should be noted that early histogenetic development of the space embryo liver had been retarded which was concluded from an enlarged lumen in bile capillaries and loose arrangement of epithelium girders as compared with the control On day-10 post flight, the flight embryos exhibited liver induration through narrowing of sinusoids lumen. Haemopoietic zones became less numerous. By the end of embryonic development these histological differences of the flight and control liver disappeared essentially. Organogenesis and histogenesis of the liver obtained from the hatchlings that had spent 5 days in microgravity did not depart from the norm. However, inability of the birds to adapt to microgravity and ensuing starvation was the reason for dystrophic changes in the liver, venous congestion and increased histoleucocytic activity. All the liver changes faded away soon alter the hatchlings were settled in favorable life conditions
authors.forename: O A
authors.initials: OA
authors.lastname: Dadasheva
authors.forename: T S
authors.initials: TS
authors.lastname: Gur'eva
authors.forename: E I
authors.initials: EI
authors.lastname: Mednikova
authors.forename: M T
authors.initials: MT
authors.lastname: Dadasheva
authors.forename: V N
authors.initials: VN
authors.lastname: Sychev
mesh_terms: D000818:Animals; D003370:Coturnix / Q000196:embryology*; D005500:Follow-Up Studies; D008099:Liver / Q000196:embryology*; D038081:Organogenesis / Q000502:physiology*; D014893:Weightlessness