title: [Studies of physical and chemical properties of the vacuum UV-irradiated molecules of human hemoglobin and its components (heme and globin)].
abstract: The purpose of the present work is to study the vacuum ultraviolet radiation action on the optical and chromatographic characteristics of human hemoglobin molecules and their components - haem and globin. Using the methods of spectrophotometry and thin layer chromatography (TLC), we have investigated into the structural changes of molecules of human hemoglobin, haem and globin, induced by the influence of vacuum UV light (gamma = 118-134 nm, dose - 1.2 kJ/m2). It has been shown that vacuum ultraviolet radiation induces an infringement of the higher types of the spatial organization ofglobin molecules, thus leading to the changes in the structural state of the albuminous globule.
authors.forename: A A
authors.initials: AA
authors.lastname: Pantiavin
authors.forename: A K
authors.initials: AK
authors.lastname: Isheeva
authors.forename: V G
authors.initials: VG
authors.lastname: Artiukhov
mesh_terms: D002855:Chromatography, Thin Layer; D005914:Globins / Q000737:chemistry / Q000528:radiation effects; D006418:Heme / Q000737:chemistry* / Q000528:radiation effects; D006454:Hemoglobins / Q000737:chemistry* / Q000528:radiation effects; D006801:Humans; D055668:Photochemical Processes; D014466:Ultraviolet Rays; D014618:Vacuum
chemical_list: D006454:Hemoglobins; D006418:Heme; D005914:Globins