title: Transplacental digoxin therapy for fetal atrial flutter with hydrops fetalis.
abstract: BACKGROUND
  Without timely treatment, fetal atrial flutter (AF) could result in congestive heart failure, hydrops fetalis and even fetal demise.
  
  
  METHODS
  Prenatal echocardiography was used to confirm AF and assess fetal cardiac function with cardiovascular profile score. Transplacental digoxin therapy was adopted, and the patient was followed up for 10 months.
  
  
  RESULTS
  The healthy male baby was delivered with normal postnatal electrocardiogram and echocardiogram. Neither arrhythmia nor neurodevelopmental impairment was found during the follow-up.
  
  
  CONCLUSIONS
  Timely transplacental digoxin therapy can successfully treat fetal AF and allow the fetus to recover from AF associated fetal heart failure and hydrops fetalis prior to delivery.
authors.affiliation: Division of Pediatric Cardiology, West China Second University Hospital, West China Medical School, Sichuan University, Chengdu, China.
authors.forename: Kai-Yu
authors.initials: KY
authors.lastname: Zhou
authors.forename: Yi-Min
authors.initials: YM
authors.lastname: Hua
authors.forename: Qi
authors.initials: Q
authors.lastname: Zhu
mesh_terms: D000328:Adult; D000889:Anti-Arrhythmia Agents / Q000008:administration & dosage*; D001282:Atrial Flutter / Q000000981:diagnostic imaging / Q000188:drug therapy*; D004077:Digoxin / Q000008:administration & dosage*; D004452:Echocardiography; D004562:Electrocardiography; D005260:Female; D005315:Fetal Diseases / Q000188:drug therapy*; D005323:Fetal Monitoring; D006801:Humans; D015160:Hydrops Fetalis / Q000000981:diagnostic imaging / Q000188:drug therapy*; D008297:Male; D008431:Maternal-Fetal Exchange; D011247:Pregnancy; D011256:Pregnancy Outcome; D016216:Ultrasonography, Prenatal
chemical_list: D000889:Anti-Arrhythmia Agents; D004077:Digoxin