title: [Serotonin and impulsivity (experiments on animals)].
abstract: In the current paper a role of the serotinergic system in organization of impulsive behaviour in animals was considered. The results of influence of antagonists and agonists of the different types and subtypes of 5-HT receptors (1A, B; 2A, B, C; 7) and the effects of the dorsal raphe nuclei lesions on characteristics of impulsivity related with a motor control, mechanisms of attention, reinforcement and decision making were summarized. The data on knock-out animals and the experiments with microdialysis have been also considered. There was emphasized the important role of interaction of 5-HT-, dopamine- and glutamatergic systems in mediation of impulsive behaviour.
authors.forename: G A
authors.initials: GA
authors.lastname: Grigor'ian
mesh_terms: D032761:Animal Experimentation; D000818:Animals; D001288:Attention / Q000187:drug effects; D001522:Behavior, Animal / Q000187:drug effects / Q000502:physiology*; D001921:Brain / Q000502:physiology*; D055786:Gene Knockout Techniques; D007175:Impulsive Behavior / Q000503:physiopathology*; D017551:Microdialysis; D009043:Motor Activity / Q000187:drug effects / Q000502:physiology; D011985:Receptors, Serotonin / Q000502:physiology*; D012701:Serotonin / Q000502:physiology*; D012702:Serotonin Antagonists / Q000494:pharmacology; D017366:Serotonin Receptor Agonists / Q000494:pharmacology
chemical_list: D011985:Receptors, Serotonin; D012702:Serotonin Antagonists; D017366:Serotonin Receptor Agonists; D012701:Serotonin