title: The effects of implementation of the Surviving Sepsis Campaign in the Netherlands.
abstract: To reduce unintentional and avoidable adverse events in patients in hospitals in the Netherlands, a patient safety agency (VMS) programme was launched in 2008. Among the VMS topics, the programme 'optimal therapy in severe sepsis', according to the international Surviving Sepsis Campaign (SSC), aims to improve early diagnosis and treatment of sepsis to reduce sepsis mortality by 15% before the end of 2012. We analysed compliance data submitted to the international SSC database from the Netherlands and compared these data with published international SS C results. Data of 863 patients, representing 6% of the international data (n=14,209), were used for analysis. In the Netherlands, the resuscitation bundle compliance improved significantly from 7% at baseline to 27% after two years (p=0.002). Internationally, the resuscitation bundle compliance increased significantly from 11 to 31% (p.
authors.affiliation: Nijmegen Institute for Infection, Inflammation, and Immunity (N4i), Radboud University Nijmegen Medical Centre, the Netherlands. m.tromp@aig.umcn.nl
authors.forename: M
authors.initials: M
authors.lastname: Tromp
authors.forename: D H T
authors.initials: DH
authors.lastname: Tjan
authors.forename: A R H
authors.initials: AR
authors.lastname: van Zanten
authors.forename: S E M
authors.initials: SE
authors.lastname: Gielen-Wijffels
authors.forename: G J D
authors.initials: GJ
authors.lastname: Goekoop
authors.forename: M
authors.initials: M
authors.lastname: van den Boogaard
authors.forename: C M
authors.initials: CM
authors.lastname: Wallenborg
authors.forename: H S
authors.initials: HS
authors.lastname: Biemond-Moeniralam
authors.forename: P
authors.initials: P
authors.lastname: Pickkers
mesh_terms: D000328:Adult; D042241:Early Diagnosis; D019983:Guideline Adherence / Q000706:statistics & numerical data; D006284:Health Plan Implementation; D017052:Hospital Mortality / Q000639:trends*; D006801:Humans; D009426:Netherlands / Q000453:epidemiology; D061214:Patient Safety / Q000592:standards*; D018805:Sepsis / Q000175:diagnosis* / Q000401:mortality / Q000628:therapy*; D016019:Survival Analysis