title: The higher expression levels of dehydroascorbate reductase and glutathione reductase in salicylic acid-deficient plants may contribute to their alleviated symptom infected with RNA viruses.
abstract: Salicylic acid (SA) is a critical signal for activation of both local and systemic resistance responses. However, SA-deficient plants adapt to RNA virus infections better, which show a less-severe symptom and less reactive oxygen species (ROS) accumulation. The higher levels of reduced glutathione (GSH) and reduced ascorbic acid (AsA) in SA-deficient plants may contribute to their alleviated symptoms, which are consistent with their higher expression levels of dehydroascorbate reductase gene (DHAR) and glutathione reductase gene (GR). High-dose AsA or GSH treatment could alleviate the symptom and inhibit virus replication after 20 days, but ROS eliminators could not imitate the effect of AsA or GSH. The data show a new link between SA and AsA/GSH-mediated redox homeostasis.
authors.affiliation: Ministry of Education Key Laboratory for Bio-Resource & Eco-Environment, College of Life Science, China.
authors.forename: Feng
authors.initials: F
authors.lastname: Zhu
authors.forename: Shu
authors.initials: S
authors.lastname: Yuan
authors.forename: Shao-Dong
authors.initials: SD
authors.lastname: Wang
authors.forename: De-Hui
authors.initials: DH
authors.lastname: Xi
authors.forename: Hong-Hui
authors.initials: HH
authors.lastname: Lin
mesh_terms: D017360:Arabidopsis / Q000187:drug effects / Q000378:metabolism; D001205:Ascorbic Acid / Q000494:pharmacology; D005978:Glutathione / Q000494:pharmacology; D005980:Glutathione Reductase / Q000235:genetics / Q000378:metabolism*; D010088:Oxidoreductases / Q000235:genetics / Q000378:metabolism; D030821:Plants, Genetically Modified / Q000235:genetics / Q000378:metabolism* / Q000821:virology; D012328:RNA Viruses / Q000472:pathogenicity*; D020156:Salicylic Acid / Q000378:metabolism*; D014779:Virus Replication / Q000187:drug effects
chemical_list: D010088:Oxidoreductases; D005980:Glutathione Reductase; C020666:glutathione dehydrogenase (ascorbate); D005978:Glutathione; D020156:Salicylic Acid; D001205:Ascorbic Acid