title: Diagnostic markers for glioblastoma.
abstract: Glioblastoma (GBM) is the most malignant form of cerebral gliomas, and despite distinct progress in surgical resection, radiation and chemotherapy, the prognosis of patients with GBM is still very poor. In the past decades knowledge of genomics and proteomics and of diagnostic, prognostic, predictive and pharmakodynamic markers measured in cerebrospinal-fluid (CSF), serum, or tumor tissue biomarkers has improved. This review briefly compiles our concepts on diagnostic markers for GBM, focusing on the latest developments.
authors.affiliation: Department of Neurosurgery, Institute of Pathology, Ruprecht-Karls-University Heidelberg and Clinical Cooperation Unit Neuropathology, German Cancer Research Center, Germany. carla.jung@med.uni-heidelberg.de
authors.forename: C S
authors.initials: CS
authors.lastname: Jung
authors.forename: A W
authors.initials: AW
authors.lastname: Unterberg
authors.forename: C
authors.initials: C
authors.lastname: Hartmann
mesh_terms: D014408:Biomarkers, Tumor / Q000032:analysis*; D001932:Brain Neoplasms / Q000175:diagnosis* / Q000378:metabolism; D005909:Glioblastoma / Q000175:diagnosis* / Q000378:metabolism; D006801:Humans
chemical_list: D014408:Biomarkers, Tumor