title: Mammary invasive ductal adenocarcinoma and vulvar invasive keratinizing squamous cell carcinoma in a woman with disseminated discoid lupus erythematosus (DDLE) - a case review.
abstract: A case of metachronous presentation of two malignancies, invasive mammary ductal adenocarcinoma and later invasive keratinizing squamous cell vulvar carcinoma, complicating a 20 years long course of disseminated discoid lupus erythematosus is described. The authors underline a potential role of long-standing immunotherapy as a factor responsible for inducing secondary neoplasia.
authors.affiliation: Department of Pathology District Specialist Hospital, Tychy, Poland. antosz@mp.pl
authors.forename: Zbigniew
authors.initials: Z
authors.lastname: Antosz
authors.forename: Ryszard
authors.initials: R
authors.lastname: Poręba
authors.forename: Waclaw
authors.initials: W
authors.lastname: Jez
authors.forename: Urszula
authors.initials: U
authors.lastname: Sioma-Markowska
mesh_terms: D000230:Adenocarcinoma / Q000276:immunology / Q000473:pathology; D001943:Breast Neoplasms / Q000276:immunology / Q000473:pathology*; D044584:Carcinoma, Ductal / Q000276:immunology / Q000473:pathology*; D002294:Carcinoma, Squamous Cell / Q000276:immunology / Q000473:pathology*; D005260:Female; D006801:Humans; D016867:Immunocompromised Host; D007166:Immunosuppressive Agents / Q000009:adverse effects; D008179:Lupus Erythematosus, Discoid / Q000150:complications* / Q000188:drug therapy; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D016609:Neoplasms, Second Primary / Q000276:immunology / Q000473:pathology*; D014846:Vulvar Neoplasms / Q000276:immunology / Q000473:pathology*
chemical_list: D007166:Immunosuppressive Agents