title: Helical tomotherapy for resected malignant pleural mesothelioma: dosimetric evaluation and toxicity.
abstract: This study evaluated adjuvant helical tomotherapy after extrapleural pneumonectomy ± neo-adjuvant chemotherapy in 24 patients with malignant pleural mesothelioma. Toxicity was judged acceptable despite 2 cases (8%) of suspected grade 5 pneumonitis. With a mean follow-up of 7 months, 5 patients had distant and 2 local and distant failure.
authors.affiliation: Department of Radiation Oncology, Hôpital Européen Georges-Pompidou, 20 rue Leblanc, Paris, France. philippe.giraud@egp.aphp.fr
authors.forename: Philippe
authors.initials: P
authors.lastname: Giraud
authors.forename: Alma
authors.initials: A
authors.lastname: Sylvestre
authors.forename: Sofia
authors.initials: S
authors.lastname: Zefkili
authors.forename: Albert
authors.initials: A
authors.lastname: Lisbona
authors.forename: Pierre
authors.initials: P
authors.lastname: Bonnette
authors.forename: Françoise
authors.initials: F
authors.lastname: Le Pimpec Barthes
authors.forename: Edouard
authors.initials: E
authors.lastname: Paris
authors.forename: Christian
authors.initials: C
authors.lastname: Perigaud
authors.forename: Alexia
authors.initials: A
authors.lastname: Savignoni
authors.forename: Marc-André
authors.initials: MA
authors.lastname: Mahé
mesh_terms: D005260:Female; D005602:France / Q000453:epidemiology; D006801:Humans; D008297:Male; D008654:Mesothelioma / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery; D008875:Middle Aged; D020360:Neoadjuvant Therapy; D009367:Neoplasm Staging; D010997:Pleural Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery; D011013:Pneumonectomy; D017564:Radiation Pneumonitis / Q000453:epidemiology; D011878:Radiotherapy / Q000379:methods*; D011879:Radiotherapy Dosage; D012189:Retrospective Studies; D017211:Treatment Failure