title: Power estimation predicts specific function action of acupuncture: an fMRI study.
abstract: OBJECTIVE
  The purpose was to investigate the distinct pattern of brain response induced by electroacupuncture stimulation (EAS) related to sustained acupuncture effects.
  
  
  METHODS
  Twenty-eight healthy volunteers were enrolled and randomized into two groups. According to grouping, volunteers were separately treated by EAS at GB37 (Guangming) or KI8 (Jiaoxin) during functional magnetic resonance imaging. Differences in acupuncture effects between the groups were tested by the power estimation approach.
  
  
  RESULTS
  Spatial patterns of the whole brain power were different in the periaqueductal gray, occipital cortex (OC) and temporal cortex when induced by EAS at GB37 and KI8. Moreover, the differences in the sustained effects between these two acupoints were also identified and associated with the OC, dorsolateral prefrontal cortex, medial prefrontal cortex, anterior cingulate cortex and insula.
  
  
  CONCLUSIONS
  Electroacupuncture stimulation induced different power fluctuation patterns related to GB37 and KI8. We suggest that these findings might be attributed to the specific function action of these acupoints.
authors.affiliation: Life Science Research Center, School of Life Science and Technology, Xidian University, Xi'an, Shaanxi 710071, China.
authors.forename: Peng
authors.initials: P
authors.lastname: Liu
authors.forename: Guangyu
authors.initials: G
authors.lastname: Zhou
authors.forename: Xuejuan
authors.initials: X
authors.lastname: Yang
authors.forename: Jixin
authors.initials: J
authors.lastname: Liu
authors.forename: Jinbo
authors.initials: J
authors.lastname: Sun
authors.forename: Minghao
authors.initials: M
authors.lastname: Dong
authors.forename: Kai
authors.initials: K
authors.lastname: Yuan
authors.forename: Yi
authors.initials: Y
authors.lastname: Zhang
authors.forename: Wei
authors.initials: W
authors.lastname: Qin
authors.forename: Jie
authors.initials: J
authors.lastname: Tian
mesh_terms: D026881:Acupuncture / Q000379:methods*; D000328:Adult; D001519:Behavior; D001921:Brain / Q000473:pathology; D001931:Brain Mapping / Q000379:methods; D003952:Diagnostic Imaging / Q000379:methods; D004594:Electrophysiology / Q000379:methods; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male