title: Efficacy of Adcon-L gel or Healon-GV in epidural fibrosis after lumbar microdiscectomy.
abstract: OBJECTIVE
  To evaluate the efficacy of anti-adhesion barrier agents following lumbar microdiscectomy.
  
  
  METHODS
  Healon GV or Adcon-L was applied to a laminectomy defect overlying the duramater in 60 patients assigned to 3 randomized groups: Group I - Adcon-L (n=21), Group II - Healon GV (n=21), and Group III - control group, no adhesion barrier used (n=18). We conducted this study between 2004 and 2006 at Selcuk University, Konya, Turkey.
  
  
  RESULTS
  No significant difference was found between the 3 groups either in the outcome measurements according to visual analogue score and the Oswestry Disability Index or in the radiological evaluation of epidural fibrosis by application of those anti-adhesion barrier agents. When comparing group III with groups I and II, we could not find a statistically significant difference in the clinical results and in the outcome measures (p>0.01).
  
  
  CONCLUSIONS
  The epidural application of popular anti-adhesion barriers, after lumbar microdiscectomy was not found to be effective regarding outcome measures in human spinal surgery.
authors.affiliation: Department of Neurosurgery, Meram Medicine Faculty, Selcuk University, A/5 Meram, Akyokus 42080, Konya, Turkey. Tel. +90 (332) 2336449. Fax. +90 (312) 4413824. Mobile. +90 (505) 5351708. E-mail: livacengiz@yahoo.com.
authors.forename: Sahika L
authors.initials: SL
authors.lastname: Cengiz
authors.forename: Alper
authors.initials: A
authors.lastname: Baysefer