title: A T-2 translational research perspective on interventions to improve post-fracture osteoporosis care.
abstract: The objectives of this paper are to: quickly outline the extent of the care gap in osteoporosis; define T-2 (knowledge) translation and its relationship to quality improvement; discuss the barriers to best practice in osteoporosis care after a fracture; convey the importance of rigor in design and evaluation of translational interventions by drawing upon examples from the broader literature; describe in some detail a series of post-fracture intervention trials conducted in Alberta, Canada; and make some conclusions specifically about osteoporosis interventions and more generally about T-2 translational research.
authors.affiliation: Department of Medicine, University of Alberta, 2F1.24 Walter Mackenzie Health Sciences Centre, University of Alberta Hospital, 8440-112th Street, Edmonton, Alberta, T6G 2B7, Canada. majumdar@ualberta.ca
authors.forename: S R
authors.initials: SR
authors.lastname: Majumdar
mesh_terms: D000368:Aged; D006620:Hip Fractures / Q000209:etiology; D006801:Humans; D008875:Middle Aged; D010024:Osteoporosis / Q000150:complications / Q000175:diagnosis / Q000628:therapy*; D058866:Osteoporotic Fractures / Q000517:prevention & control*; D058996:Quality Improvement / Q000458:organization & administration; D016032:Randomized Controlled Trials as Topic; D057170:Translational Research, Biomedical / Q000379:methods*; D014954:Wrist Injuries / Q000209:etiology