title: Investigation of the dependence of inactivation coefficient on pertinent physical quality parameters to low doses ionizing radiation.
abstract: Inactivation constant for V79 cells has been extracted from radiobiology experiments that utilize charged particles to irradiate mammal cells in vitro. Physical parameters such as effective charge, radiation mean free path and linear ionization which characterized protons and heluim-4 particles are determined using of standard values. The relationship between inactivation constant α and physical quality parameters have been determined, in this research, for protons and heluim-4 particles. This approach allows getting the characteristic biological response of inactivation of V79 cells in terms of each selected physical quality parameter. The best regression models are formulated for each obtained relationship.
authors.affiliation: Nuclear Science Programme, School of Applied Physics, University Kebangsaan Malaysia, Bangi, Selangor, Malaysia. alghoul75@yahoo.com
authors.forename: Abubaker Ali
authors.initials: AA
authors.lastname: Yousif
authors.forename: Ismail
authors.initials: I
authors.lastname: Bin Bahari
authors.forename: Muhamad Samudi
authors.initials: MS
authors.lastname: Yasir
mesh_terms: D000818:Animals; D002478:Cells, Cultured; D004307:Dose-Response Relationship, Radiation; D006371:Helium; D018499:Linear Energy Transfer; D008322:Mammals; D011522:Protons; D011829:Radiation Dosage; D011839:Radiation, Ionizing; D012062:Relative Biological Effectiveness; D055672:Static Electricity
chemical_list: D011522:Protons; D006371:Helium