title: [Chromosome analysis in 92 children with congenital mental retardation].
abstract: OBJECTIVE
  To explore the chromosome karyotypes in children with mental retardation.
  
  
  METHODS
  The peripheral blood lymphocytes from 92 children with congenital mental retardation were cultured and analysed by the G-band technique.
  
  
  RESULTS
  Of the 92 cases, 43 cases (47%) showed chromosome abnormalities. Autosomal abnormalities were found in 35 cases (38%) and sex chromosome abnormalities were found in 8 cases (9%). A novel abnormal karyotype 45, XX, psu dic (11;9) (p15;p24) was found in a child.
  
  
  CONCLUSIONS
  Chromosome abnormalities may be important cytogenetic factors for congenital mental retardation. Cytogenetic chromosome karyotypic analysis appears to be an important method for genetic screening of congenital mental retardation.
authors.affiliation: Third Military Medical University, Chongqing 400038, China.
authors.forename: Fang
authors.initials: F
authors.lastname: Wang
authors.forename: Yao
authors.initials: Y
authors.lastname: Yang
authors.forename: Xiao
authors.initials: X
authors.lastname: Yang
authors.forename: Chun-Zhi
authors.initials: CZ
authors.lastname: Wang
authors.forename: Xi-Yu
authors.initials: XY
authors.lastname: He
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D002869:Chromosome Aberrations; D005260:Female; D005820:Genetic Testing; D006801:Humans; D007223:Infant; D008607:Intellectual Disability / Q000235:genetics*; D007621:Karyotyping; D008297:Male; D012729:Sex Chromosome Aberrations