title: Evaluation of magnetic resonance imaging criteria for Meckel's cave lesion: logistic regression analysis and correlation with surgical findings.
abstract: OBJECTIVE
  Our aim was to investigate the statistical preoperative diagnostic criteria of lesions of Meckel's cave (MC) on MRI.
  
  
  METHODS
  We retrospectively reviewed the MR images with MC lesions in 34 patients. The MR signs were compared with histopathologic and surgical findings in all lesions. Odds ratio values and the confidence intervals of the MRI diagnostic criteria were evaluated by univariate logistic regression.
  
  
  RESULTS
  The following three signs of MC on post-contrast T1WI of MRI have been found to represent the most valuable criterion for determination of MC lesion: (1) contrast enhancement, (2) bulging of lateral wall, and (3) the absence of normal MC, with odds ratios of 362.67 (P<.001), 40.38 (P = .001), and 40.38 (P = .001) individually.
  
  
  CONCLUSIONS
  Contrast enhancement on post-contrast T1WI is the most sensitive MR sign for demonstrating the presence of MC lesion.
authors.affiliation: Department of Radiology, Huashan Hospital, Eye and ENT Hospital of Shanghai Medical School, Fudan University, Shanghai 200031, China. tzh518sunny@163.com
authors.forename: Zuohua
authors.initials: Z
authors.lastname: Tang
authors.forename: Xiaoyuan
authors.initials: X
authors.lastname: Feng
authors.forename: Wen
authors.initials: W
authors.lastname: Qian
authors.forename: Jichang
authors.initials: J
authors.lastname: Song
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001927:Brain Diseases / Q000175:diagnosis* / Q000473:pathology; D002426:Cavernous Sinus / Q000473:pathology*; D016009:Chi-Square Distribution; D003287:Contrast Media; D005260:Female; D006801:Humans; D016015:Logistic Models; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D012189:Retrospective Studies; D012680:Sensitivity and Specificity
chemical_list: D003287:Contrast Media