title: Potential new anticancer molecular targets for the treatment of human testicular seminomas.
abstract: In the last years novel therapeutic approaches for the treatment of cancer have been proposed: specific inhibitors of serine/threonine and tyrosine kinases, angiogenesis inhibitors, antibodies against receptors/surface molecules on cancer cells, gene therapy approaches and others. In a lot of cases the clinical trials have confirmed the efficacy of these approaches. Here, we will review the discovered new potential molecular targets for the treatment of human testicular seminomas.
authors.affiliation: Dipartimento di Medicina Sperimentale, II Università di Napoli, 80138 Naples, Italy. Paolo.Chieffi@unina2.it
authors.forename: P
authors.initials: P
authors.lastname: Chieffi
mesh_terms: D000970:Antineoplastic Agents / Q000737:chemistry / Q000494:pharmacology*; D049109:Cell Proliferation / Q000187:drug effects; D004354:Drug Screening Assays, Antitumor; D006801:Humans; D008297:Male; D018239:Seminoma / Q000188:drug therapy* / Q000473:pathology; D013329:Structure-Activity Relationship; D013736:Testicular Neoplasms / Q000188:drug therapy* / Q000473:pathology
chemical_list: D000970:Antineoplastic Agents