title: Olfactory learning-induced enhancement of the predisposition for LTP induction.
abstract: Learning of a particularly difficult olfactory-discrimination (OD) task results in acquisition of rule learning. This enhancement in learning capability is accompanied by the long-term enhancement of synaptic connectivity between piriform cortex pyramidal neurons. In this study we examined whether olfactory rule learning would modify the predisposition to induce long-term potentiation (LTP) in the pathway projecting from the piriform cortex to the olfactory bulb. We report that OD learning was associated with enhancement in the predisposition to induce LTP. This learning-related effect may be affected by process generation of new granule cells located in the olfactory bulb.
authors.affiliation: Department of Biology, Faculty of Natural Sciences, University of Haifa, Haifa 31905, Israel.
authors.forename: Yaniv
authors.initials: Y
authors.lastname: Cohen
authors.forename: Sonya
authors.initials: S
authors.lastname: Avramoav
authors.forename: Edi
authors.initials: E
authors.lastname: Barkai
authors.forename: Mouna
authors.initials: M
authors.lastname: Maroun
mesh_terms: D000704:Analysis of Variance; D000818:Animals; D001703:Biophysics; D004193:Discrimination Learning / Q000502:physiology*; D004558:Electric Stimulation; D017774:Long-Term Potentiation / Q000502:physiology*; D008297:Male; D009830:Olfactory Bulb / Q000166:cytology* / Q000502:physiology*; D009833:Olfactory Pathways / Q000502:physiology; D051381:Rats; D017207:Rats, Sprague-Dawley; D011984:Sensory Receptor Cells / Q000502:physiology*; D012903:Smell; D013569:Synapses / Q000502:physiology*; D014868:Water Deprivation