title: Clinical study of mucosa-associated lymphoid tissue lymphomas of the head and neck.
abstract: BACKGROUND
  Limited information is available on mucosa-associated lymphoid tissue lymphomas arising in the head and neck.
  
  
  METHODS
  A retrospective analysis was conducted of 20 patients who were histologically diagnosed with mucosa-associated lymphoid tissue lymphoma and treated at our institution between January 1990 and December 2009.
  
  
  RESULTS
  Treatment consisted of surgical resection alone in two patients (10 per cent), surgical resection with consecutive radiotherapy in one (5 per cent), and radiotherapy alone in eight (40 per cent). Three patients (15 per cent) were treated with systemic chemotherapy, and three (15 per cent) received chemoradiotherapy. Three patients (15 per cent) were informed of the diagnosis but not treated for their condition.
  
  
  CONCLUSIONS
  All of the 20 patients were still alive after a mean follow-up period of 50.8 months. Local treatment for mucosa-associated lymphoid tissue lymphoma of the head and neck should be the first choice in early-stage disease. However, prolonged follow up is important to determine these patients' long-term response to treatment.
authors.affiliation: Department of Otolaryngology, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan. seijih@hama-med.ac.jp
authors.forename: S
authors.initials: S
authors.lastname: Hosokawa
authors.forename: J
authors.initials: J
authors.lastname: Okamura
authors.forename: Y
authors.initials: Y
authors.lastname: Takizawa
authors.forename: G
authors.initials: G
authors.lastname: Takahashi
authors.forename: K
authors.initials: K
authors.lastname: Hosokawa
authors.forename: H
authors.initials: H
authors.lastname: Mineta
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003131:Combined Modality Therapy; D018572:Disease-Free Survival; D005260:Female; D006258:Head and Neck Neoplasms / Q000175:diagnosis / Q000401:mortality / Q000473:pathology / Q000628:therapy*; D006801:Humans; D018442:Lymphoma, B-Cell, Marginal Zone / Q000175:diagnosis / Q000401:mortality / Q000473:pathology / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D012008:Recurrence; D012189:Retrospective Studies; D015996:Survival Rate; D016896:Treatment Outcome; D055815:Young Adult