title: Comparative chemical composition and antioxidant activity of Calamintha nepeta (L.) Savi subsp. glandulosa (Req.) Nyman and Calamintha grandiflora (L.) Moench (Labiatae).
abstract: The two studied Calamintha species showed different polyphenolic content and sterol composition. Calamintha grandiflora possessed twice the polyphenolic content of Calamintha nepeta subsp. glandulosa, while the latter contained a higher number of sterols. Among them, stigmast-5-en-3β-ol was found to be the major constituent. The methanolic extract of C. grandiflora was more potent than the C. nepeta subsp. glandulosa methanolic extract in a DPPH assay, while the activity of the C. grandiflora EtOAc fraction was weaker than its C. nepeta subsp. glandulosa counterpart. Fractions of C. nepeta subsp. glandulosa showed higher activity using a β-carotene bleaching test. The petrol ether fraction of C. grandiflora showed significant inhibition of NO production.
authors.affiliation: Department of Pharmaceutical Sciences, Nutritional and Health Sciences, University of Calabria, Italy.
authors.forename: Filomena
authors.initials: F
authors.lastname: Conforti
authors.forename: Mariangela
authors.initials: M
authors.lastname: Marrelli
authors.forename: Giancarlo
authors.initials: G
authors.lastname: Statti
authors.forename: Federica
authors.initials: F
authors.lastname: Menichini
authors.forename: Dimitar
authors.initials: D
authors.lastname: Uzunov
authors.forename: Umberto
authors.initials: U
authors.lastname: Solimene
authors.forename: Francesco
authors.initials: F
authors.lastname: Menichini
mesh_terms: D000975:Antioxidants / Q000032:analysis* / Q000737:chemistry / Q000378:metabolism; D000431:Ethanol; D016166:Free Radical Scavengers / Q000378:metabolism; D020128:Inhibitory Concentration 50; D019686:Lamiaceae / Q000737:chemistry*; D000432:Methanol; D009569:Nitric Oxide / Q000378:metabolism; D010840:Phytosterols / Q000032:analysis* / Q000378:metabolism; D010936:Plant Extracts / Q000737:chemistry* / Q000494:pharmacology; D059808:Polyphenols / Q000032:analysis* / Q000378:metabolism; D013045:Species Specificity; D013265:Stigmasterol / Q000032:analysis
chemical_list: D000975:Antioxidants; D016166:Free Radical Scavengers; D010840:Phytosterols; D010936:Plant Extracts; D059808:Polyphenols; D009569:Nitric Oxide; D000431:Ethanol; D013265:Stigmasterol; D000432:Methanol