title: The role of α-, δ- and F cells in insulin secretion and action.
abstract: Nowadays, most of the basic pancreatic islet research is focused on the beta and alpha cells. Nonetheless, the pancreatic islets are complete organs with five, up to now, different cell types and dedicated vasculature and neural supply. Every cell contributes in the integration of the islet function and deserves a closer lookup in the saga of the glucose homeostasis. In this brief report we describe the current concepts about the contribution of the non-beta cells in the overall islet contribution to glucose metabolism.
authors.affiliation: Division of Endocrinology and Diabetes, Aristotle University of Thessaloniki, Thessaloniki, Greece. giovos@med.auth.gr
authors.forename: John G
authors.initials: JG
authors.lastname: Youos
mesh_terms: D000818:Animals; D050416:Glucagon-Secreting Cells / Q000378:metabolism*; D006801:Humans; D007328:Insulin / Q000378:metabolism*; D000078790:Insulin Secretion; D007515:Islets of Langerhans / Q000166:cytology*; D019864:Somatostatin-Secreting Cells / Q000378:metabolism*
chemical_list: D007328:Insulin