title: Successful treatment of Aspergillus flavus spondylodiscitis with epidural abscess in a patient with chronic granulomatous disease.
abstract: Chronic granulomatous disease is a genetic disorder characterized by defects in the ability of the phagocytes to kill ingested microbes, leading to recurrent bacterial and fungal infections. Vertebral osteomyelitis complicated by an epidural abscess from aspergillosis is rare. We report a case of Aspergillus spondylodiscitis with an epidural abscess in a 17-year-old autosomal recessive chronic granulomatous disease patient.
authors.affiliation: Department of Pediatrics, Buddhist Tzu-Chi General Hospital, Hualien, Taiwan.
authors.forename: Hsien-Mei
authors.initials: HM
authors.lastname: Chang
authors.forename: Hsin-Hui
authors.initials: HH
authors.lastname: Yu
authors.forename: Yao-Hsu
authors.initials: YH
authors.lastname: Yang
authors.forename: Wen-I
authors.initials: WI
authors.lastname: Lee
authors.forename: Jyh-Hong
authors.initials: JH
authors.lastname: Lee
authors.forename: Li-Chieh
authors.initials: LC
authors.lastname: Wang
authors.forename: Yu-Tsan
authors.initials: YT
authors.lastname: Lin
authors.forename: Bor-Luen
authors.initials: BL
authors.lastname: Chiang
mesh_terms: D000293:Adolescent; D000935:Antifungal Agents / Q000627:therapeutic use*; D001228:Aspergillosis / Q000150:complications / Q000188:drug therapy* / Q000382:microbiology; D001231:Aspergillus flavus / Q000187:drug effects*; D015299:Discitis / Q000150:complications / Q000188:drug therapy* / Q000382:microbiology; D020802:Epidural Abscess / Q000150:complications / Q000188:drug therapy* / Q000382:microbiology; D006105:Granulomatous Disease, Chronic / Q000150:complications*; D006801:Humans; D007371:Interferon-gamma / Q000627:therapeutic use*; D008159:Lumbar Vertebrae / Q000382:microbiology / Q000473:pathology; D008297:Male; D016896:Treatment Outcome
chemical_list: D000935:Antifungal Agents; D007371:Interferon-gamma