title: Molecularly imprinted solid-phase extraction coupled with HPLC for the selective determination of monobutyl phthalate in bottled water.
abstract: A molecularly imprinted polymer (MIP) was prepared using monobutyl phthalate as template. The synthesis was optimized by using different porogens and functional monomers. The MIP was used as a selective sorbent in molecularly imprinted solid-phase extraction (MIP-SPE) for pre-concentration and determination of monobutyl phthalate (mBP) from the bottled water. The difference in recognition selectivity of the polymer columns was observed in HPLC system, and the effect of the mobile phase on the performance of MIP columns was also investigated. Control of the MIP-SPE process is seen as important in helping to facilitate the selective extraction of mBP from water samples. Thereafter, the choice of washing solvent, eluting solvent amount, pH of loading sample, flow rate of loading solution and the loading sample volume was presented. The optimized procedure was described as follows: 25 mL spiked aqueous solution was percolated through the MIP-SPE cartridge at the flow rate of 1.5 mL/min. After rinsing with acetonitrile/methanol mixture (1:1, v/v), the bound analyte was desorbed with 3 mL methanol. The developed MIP-SPE method was demonstrated to be applicable for the analysis of mBP in the bottled water.
authors: Dalian Institute of Chemical Physics, Chinese Academy of Science, Dalian, P. R. China.
authors: Peipei
authors: P
authors: Qi
authors: Jincheng
authors: J
authors: Wang
authors: Yun
authors: Y
authors: Li
authors: Fan
authors: F
authors: Su
authors: Jing
authors: J
authors: Jin
authors: Jiping
authors: J
authors: Chen
mesh_terms: D000327:Adsorption; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D060766:Drinking Water / Q000737:chemistry*; D054802:Molecular Imprinting; D010795:Phthalic Acids / Q000737:chemistry* / Q000302:isolation & purification; D011108:Polymers / Q000138:chemical synthesis / Q000737:chemistry*; D052616:Solid Phase Extraction / Q000295:instrumentation / Q000379:methods*; D014874:Water Pollutants, Chemical / Q000737:chemistry* / Q000302:isolation & purification
chemical_list: D060766:Drinking Water; D010795:Phthalic Acids; D011108:Polymers; D014874:Water Pollutants, Chemical; C028577:monobutyl phthalate