title: Oligonucleotide-based label-free Hg2+ assay with a monomer-excimer fluorescence switch.
abstract: A novel fluorescent Hg(2+) sensor was developed based on the T-Hg(2+)-T structure and a thioflavine T monomer-excimer fluorescent switch. Under optimum conditions, the selectivity is remarkably high, and Hg(2+) can be quantified over the dynamic range of 0.1 to 1.2 μM, with a limit of detection (LOD) of ~20 nM and a linear correlation coefficient of 0.995.
authors: Henan Key Laboratory Cultivation Base of Nanobiological Analytical Chemistry, College of Chemistry and Chemical Engineering, Shangqiu Normal University, Shangqiu, 476000, China.
authors: Yongxiang
authors: Y
authors: Wang
authors: Fenghua
authors: F
authors: Geng
authors: Qianli
authors: Q
authors: Cheng
authors: Huiying
authors: H
authors: Xu
authors: Maotian
authors: M
authors: Xu
mesh_terms: D052160:Benzothiazoles; D006863:Hydrogen-Ion Concentration; D008628:Mercury / Q000032:analysis*; D009841:Oligonucleotides / Q000737:chemistry*; D013050:Spectrometry, Fluorescence; D013844:Thiazoles / Q000737:chemistry
chemical_list: D052160:Benzothiazoles; D009841:Oligonucleotides; D013844:Thiazoles; C009462:thioflavin T; D008628:Mercury