title: Quality improvement guidelines for percutaneous catheter-directed intra-arterial thrombolysis and mechanical thrombectomy for acute lower-limb ischemia.
abstract: Percutaneous catheter-directed intra-arterial thrombolysis is a safe and effective method of treating acute and subacute lower limb ischemia, as long as accurate patient selection and procedural monitoring are ensured. Although larger, controlled trials are needed to establish the role of PTDs in ALI, mechanical thrombectomy could currently be applied combined with lytic infusion in selected cases where rapid recanalization is required or as a stand-alone therapy when the administration of thrombolytic agents is contraindicated.
authors: Department of Radiology, Patras University Hospital, School of Medicine, Rion, Greece. karnaby@med.upatras.gr
authors: Dimitris
authors: D
authors: Karnabatidis
authors: Stavros
authors: S
authors: Spiliopoulos
authors: Dimitrios
authors: D
authors: Tsetis
authors: Dimitris
authors: D
authors: Siablis
mesh_terms: D000208:Acute Disease; D000465:Algorithms; D057785:Catheters; D003952:Diagnostic Imaging; D005343:Fibrinolytic Agents / Q000627:therapeutic use; D006801:Humans; D007511:Ischemia / Q000175:diagnosis / Q000628:therapy*; D007866:Leg / Q000098:blood supply*; D016491:Peripheral Vascular Diseases / Q000175:diagnosis / Q000628:therapy*; D058996:Quality Improvement; D017131:Thrombectomy / Q000295:instrumentation / Q000379:methods; D015912:Thrombolytic Therapy / Q000295:instrumentation / Q000379:methods*
chemical_list: D005343:Fibrinolytic Agents