title: Management of gastrointestinal leaks after minimally invasive esophagectomy: conventional treatments vs. endoscopic stenting.
abstract: BACKGROUND
  Gastrointestinal leak is a dreaded complication after esophagectomy. Conventional treatments for leak include conservative therapy, surgical reoperation, and even complete gastrointestinal (GI) diversion. The aim of this study was to evaluate the impact of endoluminal stenting in the management of esophagogastric leak after esophagectomy.
  
  
  METHODS
  Data on 18 (11.3%) of 160 patients who developed postoperative leaks after minimally invasive esophagectomy were reviewed. Indications for esophagectomy included carcinoma (n = 14), Barrett's with high-grade dysplasia (n = 3), and benign stricture (n = 1). Neoadjuvant therapy was used in 57.1% of patients with carcinoma. The first nine patients underwent conventional treatments for leak whereas the latter nine patients underwent endoscopic esophageal covered stenting as primary therapy. There were 5 cervical and 13 intrathoracic anastomotic leaks. Main outcome measures included patient characteristics, types of treatment, length of hospital stay, morbidity, and mortality.
  
  
  RESULTS
  Subjects were 16 males and 2 females with a mean age of 66 years. In the conventional treatment group, leaks were treated with neck drainage (n = 4), GI diversion (n = 2), and thoracoscopic drainage with or without repair or T-tube placement (n = 3). In the endoscopy group, all leaks were treated with endoscopic covered stenting with or without percutaneous drainage (n = 9). Control of leaks occurred in 89% of patients in the conventional treatment group vs. 100% of patients in the endoscopic stenting group. Three patients in the conventional treatment group (33%) required esophageal diversion compared to none of the patients in the endoscopy group. The 60-day or in-hospital mortality was 0% for both groups.
  
  
  CONCLUSIONS
  In our clinical practice, there has been a shift in the management of esophagogastric anastomotic leaks to nonsurgical therapy using endoscopic esophageal covered stenting. Endoluminal stenting is a safe and effective alternative in the management of GI leaks.
authors: Department of Surgery, University of California Irvine Medical Center, Orange, CA 92868, USA. ninhn@uci.edu
authors: Ninh T
authors: NT
authors: Nguyen
authors: Patrick Donohue
authors: PD
authors: Rudersdorf
authors: Brian R
authors: BR
authors: Smith
authors: Kevin
authors: K
authors: Reavis
authors: Xuan-Mai T
authors: XM
authors: Nguyen
authors: Michael J
authors: MJ
authors: Stamos
mesh_terms: D000368:Aged; D057868:Anastomotic Leak / Q000209:etiology / Q000401:mortality / Q000628:therapy*; D001471:Barrett Esophagus / Q000601:surgery; D002277:Carcinoma / Q000601:surgery*; D004322:Drainage; D016099:Endoscopy, Gastrointestinal; D004938:Esophageal Neoplasms / Q000601:surgery*; D004940:Esophageal Stenosis / Q000601:surgery; D016629:Esophagectomy / Q000009:adverse effects*; D005260:Female; D017052:Hospital Mortality; D006801:Humans; D007902:Length of Stay; D008297:Male; D015607:Stents