title: Method to predict the chance of developing a male profile out of mixtures of male and female DNA.
abstract: In forensic examination it is a standard to take vaginal swabs from victims of sexual assault for further molecular genetic analysis. Laboratories then are usually confronted with mixtures of lots of female and only a small amount of male DNA. Nowadays it is possible to work with specific Y chromosomal markers after DNA extraction by differential lysis. The determined ratio of autosomal DNA and Y chromosomal DNA can be used to identify the possibility of generating a male profile in these samples.
authors: Kantonsspital St. Gallen, Institute of Legal Medicine St. Gallen, St. Gallen, Switzerland. patrick.laberke@kssg.ch
authors: Patrick Johannes
authors: PJ
authors: Laberke
authors: Rahel
authors: R
authors: Grossenbacher
authors: Roland
authors: R
authors: Hausmann
authors: Beate
authors: B
authors: Balitzki
mesh_terms: D001769:Blood; D041322:Chromosomes, Human, Y / Q000235:genetics*; D016172:DNA Fingerprinting; D005260:Female; D005554:Forensic Medicine / Q000379:methods*; D006801:Humans; D008297:Male; D011902:Rape; D013094:Spermatozoa; D020080:Tandem Repeat Sequences; D014626:Vaginal Smears