title: Survival trends of cancer amongst the south Asian and non-south Asian population under 30 years of age in Yorkshire, UK.
abstract: BACKGROUND
  Several studies have shown differences in survival trends between ethnic groups across adults with cancer in the UK. It is unclear whether these differences exist exclusively in the older adult population or whether they begin to emerge in children and young adults.
  
  
  METHODS
  Subjects (n=3534) diagnosed with cancer under 30 years of age in Yorkshire between 1990 and 2005 were analysed. Differences in survival rates for diagnostic subgroups were estimated by ethnic group (south Asian or not) using Kaplan-Meier estimation and Cox regression.
  
  
  RESULTS
  When compared to non-south Asians (all other ethnic groups excluding south Asians) a significant increased risk of death was seen for south Asians with leukaemia (hazard ratio (HR)=1.75; 95% confidence interval (CI)=1.11-2.76) and lymphoma (HR=2.05; 95% CI=1.09-3.87), whereas south Asians with solid tumours other than central nervous system tumours had a significantly reduced risk of death(HR=0.50; 95% CI=0.28-0.89). This was independent of socioeconomic deprivation.
  
  
  CONCLUSIONS
  We found evidence of poorer survival outcomes for south Asians compared to non-south Asian children and young adults with leukaemia and lymphoma, but better outcomes for south Asian children and young adults with other solid tumours. This needs to be explained, and carefully addressed in the on-going development of cancer services.
authors: Paediatric Epidemiology Group, Division of Epidemiology, Room 8.49, Worsley Building, Clarendon Way, University of Leeds, LS2 9NL, UK. m.vanlaar@leeds.ac.uk
authors: M
authors: M
authors: van Laar
authors: P A
authors: PA
authors: McKinney
authors: D P
authors: DP
authors: Stark
authors: A
authors: A
authors: Glaser
authors: S E
authors: SE
authors: Kinsey
authors: I J
authors: IJ
authors: Lewis
authors: S V
authors: SV
authors: Picton
authors: M
authors: M
authors: Richards
authors: P D
authors: PD
authors: Norman
authors: R G
authors: RG
authors: Feltbower
mesh_terms: D000293:Adolescent; D000328:Adult; D001208:Asia / Q000208:ethnology; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D009369:Neoplasms / Q000453:epidemiology / Q000208:ethnology / Q000401:mortality*; D016019:Survival Analysis; D006113:United Kingdom / Q000453:epidemiology; D055815:Young Adult