title: Absence of human papillomavirus sequences in epithelial breast cancer in a Mexican female population.
abstract: The role of human papillomavirus (HPV) in breast cancer is controversial. We evaluated 118 breast carcinomas and two paraffin-embedded tissues of lesions of the nipple of Mexican patients for HPV sequences. No carcinoma sample exhibited koilocytosis, in contrast to lesions of the nipple. We subjected purified DNAs to PCR employing two HPV16/E6 or GP5/6 primer set oligonucleotides. Results showed that HPV DNA sequences were absent in the breast tissues. Absence of HPV in breast carcinoma failed to support an association between HPV infection and this carcinoma.
authors: División de Investigación en Salud, Unidad Médica de Alta Especialidad, Hospital de Especialidades General de División Manuel Ávila Camacho, Instituto Mexicano del Seguro Social, Puebla, Mexico.
authors: Lisbeth
authors: L
authors: Herrera-Romano
authors: Nora
authors: N
authors: Fernández-Tamayo
authors: Eduardo
authors: E
authors: Gómez-Conde
authors: Juan M
authors: JM
authors: Reyes-Cardoso
authors: Felipe
authors: F
authors: Ortiz-Gutierrez
authors: Guillermo
authors: G
authors: Ceballos
authors: Alejandra
authors: A
authors: Valdivia
authors: Patricia
authors: P
authors: Piña
authors: Mauricio
authors: M
authors: Salcedo
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001943:Breast Neoplasms / Q000821:virology*; D018270:Carcinoma, Ductal, Breast / Q000821:virology*; D004279:DNA, Viral / Q000032:analysis; D005260:Female; D006801:Humans; D008800:Mexico; D008875:Middle Aged; D027383:Papillomaviridae; D030361:Papillomavirus Infections / Q000453:epidemiology*; D016133:Polymerase Chain Reaction
chemical_list: D004279:DNA, Viral