title: A 7-year-old girl with subcutaneous emphysema, pneumomediastinum, pneumothorax, and pneumoretroperitoneum caused by Mycoplasma pneumoniae pneumonia.
abstract: A 7-year-old girl presented with subcutaneous emphysema, pneumomediastinum (PM), pneumoretroperitoneum, and pneumothorax caused by Mycoplasma pneumoniae (MP). The patient had been treated with clarithromycin for pneumonia at another hospital; however, her condition deteriorated and complications developed. Soon after admission to our hospital, we started the patient on minocycline and prednisolone, and the complications improved promptly. Laboratory data showed serum ferritin and urinary beta-2-microglobulin levels were greatly elevated. We therefore speculated that the patient might have underlying hypercytokinemia. Prednisolone is an effective treatment for hypercytokinemia. We therefore recommend prednisolone treatment for cases of severe M. pneumoniae pneumonia that do not respond to antimicrobial agents.
authors: Department of General Pediatrics, Nihon University Nerima-Hikarigaoka Hospital, 2-11-1 Nerima-ku, Tokyo 179-0072, Japan. y-inamo@pb3.so-net.ne.jp
authors: Yasuji
authors: Y
authors: Inamo
authors: Yoshiaki
authors: Y
authors: Ishizuka
authors: Koji
authors: K
authors: Hashimoto
authors: Maki
authors: M
authors: Hasegawa
authors: Katsuya
authors: K
authors: Saito
authors: Tomoko
authors: T
authors: Kida
authors: Ayako
authors: A
authors: Nakamura
authors: Teruaki
authors: T
authors: Ishikawa
authors: Tatsuo
authors: T
authors: Fuchigami
mesh_terms: D002648:Child; D005260:Female; D006801:Humans; D008478:Mediastinal Emphysema / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology; D009177:Mycoplasma pneumoniae; D011019:Pneumonia, Mycoplasma / Q000150:complications* / Q000000981:diagnostic imaging / Q000382:microbiology; D011030:Pneumothorax / Q000000981:diagnostic imaging / Q000209:etiology*; D011859:Radiography; D012188:Retropneumoperitoneum / Q000000981:diagnostic imaging / Q000209:etiology*; D013352:Subcutaneous Emphysema / Q000000981:diagnostic imaging* / Q000209:etiology*