title: Posterior capsule opacification and capsular bag performance of a microincision intraocular lens.
abstract: OBJECTIVE
  To assess the axial stability and posterior capsule opacification (PCO)-inhibiting efficacy of a microincision hydrophilic intraocular lens (IOL) (Idea 613 XC) and a standard hydrophobic open-loop acrylic IOL (Acrysof SA60AT).
  
  
  METHODS
  Moorfields Eye Hospital NHS Foundation Trust, London, United Kingdom.
  
  
  METHODS
  Clinical trial.
  
  
  METHODS
  Patients with bilateral cataract received a microincision cataract surgery (MICS) IOL in 1 eye and a small-incision cataract surgery (SICS) IOL in the contralateral eye. Follow-up examinations were performed immediately after surgery and postoperatively at 1 week and 3 and 24 months. Posterior capsule opacification was assessed using retroillumination photography. Anterior chamber depth (ACD) was measured using partial coherence laser interferometry, and IOL tilt and decentration were measured using a Purkinje meter.
  
  
  RESULTS
  Seventy eyes (35 patients) were enrolled. The mean ACD at 3 months was 4.91 mm ± 0.26 (SD) in the MICS group and 4.60 ± 0.23 mm in the SICS group. The anterior IOL shift over the first 3 months was slightly smaller with the MICS IOL (81 μm) than with the SICS IOL (254 μm). The mean ACD was 0.377 ± 178 μm deeper with the MICS IOL (P<.01, paired t test). Two years postoperatively, the amount of regeneratory PCO was higher with the MICS IOL than with the SICS IOL (image analysis software score 2.6 versus 1.9; P=.005).
  
  
  CONCLUSIONS
  Two years after surgery, the PCO rate was slightly higher with the MICS IOL. The 2 IOLs had similar performance in terms of axial stability, decentration, and tilt.
  
  
  BACKGROUND
  No author has a financial or proprietary interest in any material or method mentioned. Additional disclosures are found in the footnotes.
authors: Moorfields Eye Hospital NHS Foundation Trust, London, United Kingdom.
authors: Vinod
authors: V
authors: Gangwani
authors: Nino
authors: N
authors: Hirnschall
authors: John
authors: J
authors: Koshy
authors: Alja
authors: A
authors: Crnej
authors: Yutaro
authors: Y
authors: Nishi
authors: Vincenzo
authors: V
authors: Maurino
authors: Oliver
authors: O
authors: Findl
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000867:Anterior Chamber / Q000473:pathology; D058442:Capsule Opacification / Q000209:etiology* / Q000601:surgery; D004311:Double-Blind Method; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007368:Interferometry; D053685:Laser Therapy; D053844:Lasers, Solid-State; D019654:Lens Implantation, Intraocular; D007910:Lenses, Intraocular / Q000009:adverse effects*; D008027:Light; D008297:Male; D008866:Microsurgery / Q000379:methods; D008875:Middle Aged; D018918:Phacoemulsification / Q000379:methods*; D057852:Posterior Capsule of the Lens / Q000473:pathology*; D011474:Prosthesis Design; D019591:Pseudophakia / Q000503:physiopathology; D012029:Refraction, Ocular / Q000502:physiology; D014792:Visual Acuity / Q000502:physiology