title: Prevalence, incidence, and recurrence of oral lesions among HIV-infected patients on HAART in Alabama: a two-year longitudinal study.
abstract: OBJECTIVE
  Our aim was to quantify prevalence, incidence, and recurrence of oral lesions (OL) among a population in the Southeast.
  
  
  METHODS
  A retrospective study based on chart review was conducted among patients (n = 744) who were ≥19 years of age and initiated highly active antiretroviral therapy (HAART) between January 2000 and June 2006 at the University of Alabama at Birmingham (UAB) 1917 Clinic. Patients' laboratory data and oral conditions were recorded for 2 years after enrollment into the study.
  
  
  RESULTS
  During 2 years of follow-up, the period prevalence of individuals experienced at least one OL was 35.6% (266/744). Among all of the 374 episodes of OL, 183 were new cases, while 57 were recurrences. The OL person-visit incidence rate was 0.02 per 100 person-visits. Oropharyngeal candidiasis (OPC) was the most frequent manifestation in terms of period prevalence (74.9%) with a person-visit incident rate of 0.01 per 100 person-visits.
  
  
  CONCLUSIONS
  Patients undergoing HAART continue to be affected by HIV-related oral conditions, especially OPC. These results clearly indicate that OL during HIV infection are still highly prevalent in spite of the improvements in medical care and the availability of HAART.
authors: Department of Epidemiology, School of Public Health, University of Alabama at Birmingham, Birmingham, Alabama, USA. irene.tami@fulbrightmail.org
authors: Irene M
authors: IM
authors: Tamí-Maury
authors: James H
authors: JH
authors: Willig
authors: Pauline E
authors: PE
authors: Jolly
authors: Sten
authors: S
authors: Vermund
authors: Inmaculada
authors: I
authors: Aban
authors: Jeffery D
authors: JD
authors: Hill
authors: Craig M
authors: CM
authors: Wilson
authors: Mirjam-Collette
authors: MC
authors: Kempf
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000150:complications / Q000453:epidemiology*; D000328:Adult; D000368:Aged; D000407:Alabama / Q000453:epidemiology; D023241:Antiretroviral Therapy, Highly Active; D002180:Candidiasis, Oral / Q000150:complications / Q000453:epidemiology; D005260:Female; D015658:HIV Infections / Q000150:complications / Q000188:drug therapy*; D006801:Humans; D015994:Incidence; D017733:Leukoplakia, Hairy / Q000150:complications / Q000453:epidemiology; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D009059:Mouth Diseases / Q000150:complications / Q000453:epidemiology*; D009819:Office Visits; D019226:Oral Ulcer / Q000150:complications / Q000453:epidemiology; D015995:Prevalence; D012008:Recurrence; D012189:Retrospective Studies; D013283:Stomatitis, Herpetic / Q000150:complications / Q000453:epidemiology; D055815:Young Adult