title: Toxicology in the ICU: Part 1: general overview and approach to treatment.
abstract: Poisonings, adverse drug effects, and envenomations continue to be commonly encountered. Patients often present critically ill and warrant ICU admission. Many other patients who are initially stable have the potential for rapid deterioration and require continuous cardiopulmonary and neurologic monitoring. Given the potential for rapid deterioration, and because patients need continuous monitoring, ICU admission is frequently required. This article is the first of a three-part series to be published in CHEST; it discusses general management, laboratory tests, enhanced elimination, and emerging therapies. The second article will address the management of specific overdoses; the last will cover plants, mushrooms, envenomations, and heavy metals.
authors: Department of Medical Toxicology, Banner Good Samaritan Medical Center, Phoenix, AZ. Electronic address: michael.levine@bannerhealth.com.
authors: Michael
authors: M
authors: Levine
authors: Department of Medical Toxicology, Banner Good Samaritan Medical Center, Phoenix, AZ.
authors: Daniel E
authors: DE
authors: Brooks
authors: Department of Medical Toxicology, Banner Good Samaritan Medical Center, Phoenix, AZ.
authors: Carrie A
authors: CA
authors: Truitt
authors: Division of Medical Toxicology, Department of Emergency Medicine, University of Massachusetts, Worcester, MA.
authors: Brian J
authors: BJ
authors: Wolk
authors: Division of Medical Toxicology, Department of Emergency Medicine, University of Massachusetts, Worcester, MA.
authors: Edward W
authors: EW
authors: Boyer
authors: Department of Medical Toxicology, Banner Good Samaritan Medical Center, Phoenix, AZ.
authors: Anne-Michelle
authors: AM
authors: Ruha
mesh_terms: D000136:Acid-Base Equilibrium; D000138:Acidosis / Q000209:etiology; D005217:Fat Emulsions, Intravenous; D006801:Humans; D006879:Hydroxocobalamin; D007362:Intensive Care Units; D009270:Naloxone / Q000008:administration & dosage; D009292:Narcotic Antagonists / Q000008:administration & dosage; D009459:Neuroleptic Malignant Syndrome / Q000628:therapy; D009994:Osmolar Concentration; D011041:Poisoning / Q000503:physiopathology / Q000628:therapy*; D006435:Renal Dialysis; D020230:Serotonin Syndrome / Q000628:therapy; D007507:Therapeutic Irrigation; D015262:Xenobiotics
chemical_list: D005217:Fat Emulsions, Intravenous; D009292:Narcotic Antagonists; D015262:Xenobiotics; D009270:Naloxone; D006879:Hydroxocobalamin