title: Aspergillus oryzae laeA regulates kojic acid synthesis genes.
abstract: Kojic acid synthesis genes regulation was investigated in Aspergillus oryzae. Our results indicate that kojic acid production was lost in the laeA disruption strain, but was recovered in the LaeA complement strain. Real-time PCR also confirmed that expression of kojic acid biosynthesis genes decreased in the laeA disruption strain, indicating that these genes are under the control of LaeA.
authors: Genome Biotechnology Laboratory, Kanazawa Institute of Technology.
authors: Ken
authors: K
authors: Oda
authors: Akiko
authors: A
authors: Kobayashi
authors: Shinichi
authors: S
authors: Ohashi
authors: Motoaki
authors: M
authors: Sano
mesh_terms: D001236:Aspergillus oryzae / Q000201:enzymology / Q000235:genetics; D005656:Fungal Proteins / Q000235:genetics / Q000378:metabolism*; D017353:Gene Deletion; D015966:Gene Expression Regulation, Fungal; D005816:Genetic Complementation Test; D008780:Methyltransferases / Q000235:genetics / Q000378:metabolism*; D020161:Physical Chromosome Mapping; D011753:Pyrones / Q000378:metabolism*; D060888:Real-Time Polymerase Chain Reaction
chemical_list: D005656:Fungal Proteins; D011753:Pyrones; C011890:kojic acid; D008780:Methyltransferases