title: Xpert MTB/RIF for rapid diagnosis of tuberculous lymphadenitis from fine-needle-aspiration biopsy specimens.
abstract: This study demonstrates the excellent diagnostic accuracy of the Xpert MTB/RIF test in patients with tuberculous lymphadenitis. The test sensitivity and specificity were 96.7% (95% confidence interval [CI], 86.6 to 100%) and 88.9% (95% CI, 69.6 to 100%), respectively, and it correctly identified 6/6 (100%) of the cytology smear-negative/culture-positive cases and 1 of 2 (50%) rifampin-resistant cases.
authors: Division of Anatomical Pathology, National Health Laboratory Service, Tygerberg Hospital, Tygerberg, Cape Town, South Africa. louisligthelm@sun.ac.za
authors: Louis J
authors: LJ
authors: Ligthelm
authors: Mark P
authors: MP
authors: Nicol
authors: Kim G P
authors: KG
authors: Hoek
authors: Rachael
authors: R
authors: Jacobson
authors: Paul D
authors: PD
authors: van Helden
authors: Ben J
authors: BJ
authors: Marais
authors: Robin M
authors: RM
authors: Warren
authors: Colleen A
authors: CA
authors: Wright
mesh_terms: D000293:Adolescent; D000328:Adult; D000995:Antitubercular Agents / Q000494:pharmacology; D001431:Bacteriological Techniques / Q000379:methods*; D044963:Biopsy, Fine-Needle; D002648:Child; D002675:Child, Preschool; D024881:Drug Resistance, Bacterial; D005260:Female; D006801:Humans; D008297:Male; D025202:Molecular Diagnostic Techniques / Q000379:methods*; D009169:Mycobacterium tuberculosis / Q000235:genetics / Q000302:isolation & purification*; D011933:Reagent Kits, Diagnostic; D012293:Rifampin / Q000494:pharmacology; D012680:Sensitivity and Specificity; D014388:Tuberculosis, Lymph Node / Q000175:diagnosis*; D055815:Young Adult
chemical_list: D000995:Antitubercular Agents; D011933:Reagent Kits, Diagnostic; D012293:Rifampin