title: Nodular glomerulosclerosis in a non-diabetic hypertensive smoker with dyslipidemia.
abstract: Nodular glomerulosclerosis may be idiopathic or develop associated with diabetes mellitus, membranoprolipherative glomerulonephritis, light or heavy chain deposits, amyloidosis, fibrillary or immunotactoide disease, and Takayasu's arteritis. Histological features of idiopathic nodular glomerulosclerosis are similar to the Kimmelstiel-Wilson changes. Recent evidence points to the role of hyperglycemia, hyperlipidemia, hypertension and smoking in the mechanisms of this uncommon condition. The case study of a 65-year-old male presenting recent arterial hypertension and nodular non-diabetic glomerulosclerosis is described, and the possible role of heavy smoking in the pathogenesis of this condition is emphasized.
authors: Universidade Estadual de Ciências da Saúde de Alagoas, Maceió-AL, Brazil.
authors: A Falcão Pedrosa
authors: AF
authors: Costa
authors: W Albert
authors: WA
authors: Gomes dos Santos
authors: M A Gonçalves Pontes
authors: MA
authors: Filho
authors: F Teles
authors: FT
authors: Farias
authors: V
authors: V
authors: Modesto dos Santos
mesh_terms: D003928:Diabetic Nephropathies / Q000209:etiology*; D050171:Dyslipidemias / Q000150:complications*; D006801:Humans; D006973:Hypertension / Q000150:complications*; D008297:Male; D008875:Middle Aged; D012907:Smoking / Q000009:adverse effects*