title: Development of biological standards for the quality assurance of presumptive testing reagents.
abstract: Forensic scientists periodically check working test reagents with known or standards to verify that the presumptive testing reagents are working properly. Often times, this is done with a neat body fluid such as blood or saliva that is dried onto a swab and kept in a freezer. The problem with this practice is that a degrading test reagent, for example acid phosphatase testing reagent, may test positive on a neat standard but miss a weak semen stain from a case. To ensure that presumptive testing reagents are working properly, a series of "weak" standards have been developed for the testing of acid phosphatase, amylase, creatinine and hemoglobin. The preparation and use of these biological standards will be discussed.
authors: Ohio Attorney General's Office, Ohio Bureau of Criminal Identification and Investigation, Richfield, OH, USA.
authors: Dale L
authors: DL
authors: Laux
mesh_terms: D000135:Acid Phosphatase / Q000378:metabolism; D000681:Amylases / Q000378:metabolism; D001769:Blood; D003404:Creatinine / Q000378:metabolism; D044707:Forensic Sciences / Q000592:standards*; D006454:Hemoglobins / Q000378:metabolism; D006801:Humans; D007202:Indicators and Reagents / Q000592:standards*; D011786:Quality Control; D012463:Saliva / Q000378:metabolism; D012661:Semen / Q000378:metabolism
chemical_list: D006454:Hemoglobins; D007202:Indicators and Reagents; D003404:Creatinine; D000135:Acid Phosphatase; D000681:Amylases