title: Plasma carotenoid concentrations before and after supplementation with astaxanthin in middle-aged and senior subjects.
abstract: A randomized, double-blind human trial was conducted to assess the effect on the plasma carotenoid concentration of 4- or 12-week astaxanthin supplementation (1 or 3 mg/d) of 20 Japanese middle-aged and senior subjects. The plasma carotenoid concentration was significantly higher after the astaxanthin supplementation than that before in both the 1 mg/d (10 subjects) and 3 mg/d (10 subjects) groups.
authors: Food and Biodynamic Chemistry Laboratory, Graduate School of Agricultural Science, Tohoku University.
authors: Taiki
authors: T
authors: Miyazawa
authors: Kiyotaka
authors: K
authors: Nakagawa
authors: Fumiko
authors: F
authors: Kimura
authors: Akira
authors: A
authors: Satoh
authors: Teruo
authors: T
authors: Miyazawa
mesh_terms: D000284:Administration, Oral; D000368:Aged; D000975:Antioxidants / Q000737:chemistry / Q000378:metabolism*; D001682:Biological Availability; D002338:Carotenoids / Q000097:blood; D002851:Chromatography, High Pressure Liquid; D019587:Dietary Supplements; D004311:Double-Blind Method; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D007564:Japan; D014975:Lutein / Q000097:blood; D000077276:Lycopene; D008297:Male; D008875:Middle Aged; D018384:Oxidative Stress / Q000187:drug effects; D053719:Tandem Mass Spectrometry; D024341:Xanthophylls / Q000008:administration & dosage / Q000097:blood / Q000493:pharmacokinetics; D019207:beta Carotene / Q000097:blood
chemical_list: D000975:Antioxidants; D024341:Xanthophylls; D019207:beta Carotene; D002338:Carotenoids; C005948:astaxanthine; D000077276:Lycopene; D014975:Lutein