title: Use of alkyl 2,4,6-triisopropylbenzoates in the asymmetric homologation of challenging boronic esters.
abstract: (-)-Sparteine induced lithiation of primary 2,4,6-triisopropylbenzoates and subsequent homologation of boronic esters is reported. A comparative study with lithiated N,N-diisopropylcarbamates has demonstrated the superiority of the hindered benzoate.
authors: School of Chemistry, University of Bristol, Cantock's Close, Bristol, BS8 1TS, UK.
authors: Robin
authors: R
authors: Larouche-Gauthier
authors: Catherine J
authors: CJ
authors: Fletcher
authors: Irantzu
authors: I
authors: Couto
authors: Varinder K
authors: VK
authors: Aggarwal
mesh_terms: D000478:Alkylation; D001565:Benzoates / Q000737:chemistry*; D001896:Boron Compounds / Q000737:chemistry*; D004952:Esters; D007700:Kinetics
chemical_list: D001565:Benzoates; D001896:Boron Compounds; D004952:Esters