title: Patent ductus arteriosus in a family of Chihuahuas.
abstract: This report describes a patent ductus arteriosus (PDA) in four puppies from the same family of Chihuahuas, bred from the same mother and from two different litters. Identification of this congenital anomaly relies on clinical examination, radiography and ultrasonography. Three of these puppies were female, and had a type-1 PDA. A conventional surgical ligation was performed on one of them, whilst the others underwent no treatment. One puppy was male, and presented with a type-4 PDA, requiring euthanasia. Post-mortem examination and histopathological examination of the PDA allowed characterisation of the histological anomalies, which were identical to those described in other breeds. The mother and the two stud dogs were not affected. Even though the mode of transmission has not been fully identified, it is evident that this PDA is hereditary in nature. To the authors' knowledge this is the first description of this congenital cardiopathy in a family of this breed, and in a significant number of first-generation individuals.
authors: Centre Hospitalier Vétérinaire des Cordeliers, 29 Avenue du Maréchal Joffre, F-77100 Meaux, France.
authors: E
authors: E
authors: Bomassi
authors: S
authors: S
authors: Libermann
authors: C
authors: C
authors: Bille
authors: E
authors: E
authors: Rattez
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D004283:Dog Diseases / Q000151:congenital* / Q000473:pathology / Q000601:surgery; D004285:Dogs; D004374:Ductus Arteriosus, Patent / Q000473:pathology / Q000601:surgery / Q000662:veterinary*; D017809:Fatal Outcome; D005260:Female; D020022:Genetic Predisposition to Disease; D008297:Male; D016896:Treatment Outcome