title: Microfluidic platforms for performing surface-based clinical assays.
abstract: The need for fast, specific and portable diagnostic systems for clinical assays has, in recent years, led to an explosion of research into microfluidic chip-based immunoassays towards rapid point-of-care analysis. Such devices exploit small dimensions, superior fluidic control and low reagent volumes to allow a number of clinically important procedures to be achieved with improvements on conventional methods, many of which rely on the surface-based binding of antigens to antibodies. Here, we discuss recent developments and innovations in the area of on-chip surface-based immunoassays and provide an outlook on the potential of such platforms for future diagnostics.
authors: Department of Chemistry, University of Hull, Cottingham Road, Hull, HU6 7RX, UK.
authors: Mark D
authors: MD
authors: Tarn
authors: Nicole
authors: N
authors: Pamme
mesh_terms: D006801:Humans; D007118:Immunoassay; D007159:Immunologic Tests; D046208:Microchip Analytical Procedures; D046210:Microfluidic Analytical Techniques; D044085:Microfluidics