title: Structural reassignment of cytosporolides A-C via biomimetic synthetic studies and reinterpretation of NMR data.
abstract: A structure revision for the recently isolated fungal meroterpenoids, cytosporolides A-C, is suggested based on biosynthetic speculation and reinterpretation of existing spectroscopic data. The structure revision is supported by a biomimetic synthetic study, featuring a [4 + 2] cycloaddition reaction between a presumed o-quinone methide intermediate and β-caryophyllene.
authors: Discipline of Chemistry, School of Chemistry & Physics, University of Adelaide, North Terrace, Adelaide SA 5005, Australia.
authors: Justin T J
authors: JT
authors: Spence
authors: Jonathan H
authors: JH
authors: George
mesh_terms: D040761:Biomimetic Materials / Q000138:chemical synthesis*; D003500:Cyclization; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D000081223:Polycyclic Sesquiterpenes; D012717:Sesquiterpenes / Q000138:chemical synthesis*
chemical_list: D000081223:Polycyclic Sesquiterpenes; D012717:Sesquiterpenes; C569249:cytosporolide A; C569250:cytosporolide B; C569251:cytosporolide C; C024714:caryophyllene