title: Linear immunoglobulin a bullous disease of childhood responsive to intravenous immunoglobulin monotherapy.
abstract: We report a case of linear immunoglobulin A bullous disease in a 9-year-old boy who presented with rapidly progressive severe disease and could not tolerate dapsone because of high liver enzymes within a week after a low dose of dapsone in association with an underlying fatty liver. He showed remarkable improvement with intravenous immunoglobulins used as monotherapy, with a rapid clearance and a sustained remission after stopping the treatment.
authors: As'ad Al-Hamad Dermatology Center, Al-Sabah Hospital, Kuwait. artinanda@hotmail.com
authors: Arti
authors: A
authors: Nanda
authors: Fatima
authors: F
authors: Khawaja
authors: Mousmee
authors: M
authors: Nanda
authors: Humoud
authors: H
authors: Al-Sabah
authors: Mohamed K
authors: MK
authors: Selim
authors: Richard
authors: R
authors: Dvorak
authors: Qasem A
authors: QA
authors: Alsaleh
mesh_terms: D002648:Child; D000075202:Contraindications; D003622:Dapsone / Q000009:adverse effects; D005493:Folic Acid Antagonists / Q000009:adverse effects; D006801:Humans; D007070:Immunoglobulin A / Q000276:immunology*; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use*; D008297:Male; D012074:Remission Induction; D012872:Skin Diseases, Vesiculobullous / Q000188:drug therapy* / Q000276:immunology* / Q000473:pathology
chemical_list: D005493:Folic Acid Antagonists; D007070:Immunoglobulin A; D016756:Immunoglobulins, Intravenous; D003622:Dapsone