title: [Hypertension, obesity, erectile dysfunction. What kind of drug to choose].
abstract: Hypertension is one of the most common cardiovascular diseases. The development and progression of hypertension is associated with prolonged hyper activation of the renin-angiotensin-aldosterone system. ACE inhibitors and angiotensin receptor blockers (ARBs) are highly effective medicines and are widely used in the treatment of cardiovascular diseases: hypertension, congestive heart failure, coronary heart disease. The main pharmacological effects of ACE inhibitors and ARBs are hypotensive, neurohumoral, antiproliferative, cardio- and nefroprotective functions, as well as constantly improving endothelial function. In accordance with the article, hypertensive effectiveness, tolerability and organ-protective properties of valsartan are noticeable among patients with hypertension, obesity and erectile dysfunction, taking this medicine.
authors: M L
authors: ML
authors: Maksimov
authors: A S
authors: AS
authors: Ermolaeva
authors: O V
authors: OV
authors: Dralova
mesh_terms: D057911:Angiotensin Receptor Antagonists / Q000008:administration & dosage / Q000009:adverse effects / Q000493:pharmacokinetics; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000008:administration & dosage / Q000009:adverse effects / Q000493:pharmacokinetics; D000959:Antihypertensive Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000493:pharmacokinetics; D001794:Blood Pressure / Q000187:drug effects; D007172:Erectile Dysfunction / Q000150:complications / Q000188:drug therapy* / Q000378:metabolism; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000188:drug therapy* / Q000378:metabolism; D008297:Male; D009765:Obesity / Q000150:complications / Q000188:drug therapy* / Q000378:metabolism; D012084:Renin-Angiotensin System / Q000187:drug effects*; D012307:Risk Factors; D013777:Tetrazoles / Q000008:administration & dosage / Q000009:adverse effects / Q000493:pharmacokinetics; D014633:Valine / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives / Q000493:pharmacokinetics; D000068756:Valsartan
chemical_list: D057911:Angiotensin Receptor Antagonists; D000806:Angiotensin-Converting Enzyme Inhibitors; D000959:Antihypertensive Agents; D013777:Tetrazoles; D000068756:Valsartan; D014633:Valine