title: [Subcutaneous implanted system for the treatment of type 2 diabetes].
abstract: Type 2 diabetes is a complex metabolic disorder characterized by hyperglycemia arising from a combination of insufficient insulin secretion and resistance to insulin action. Insulin has become an important agent in treating this disease, but long-term administration of insulin not only brings pain and inconvenience to the patients but also causes local adipose tissue atrophy and scleroma. Therefore, novel delivery method has become a hot topic, mainly including improving delivery systems, developing new recombinant insulin, and changing the route of administration. This article introduces DUROS (an implanted delivery system), a new route of drug administration.
authors: Department of Endocrinology, The First Hospital of Jilin University, Changchun, China.
authors: Yan
authors: Y
authors: Li
authors: Hui
authors: H
authors: Guo
mesh_terms: D003924:Diabetes Mellitus, Type 2 / Q000188:drug therapy*; D006801:Humans; D007004:Hypoglycemic Agents / Q000008:administration & dosage / Q000627:therapeutic use; D007328:Insulin / Q000008:administration & dosage / Q000627:therapeutic use; D007332:Insulin Infusion Systems
chemical_list: D007004:Hypoglycemic Agents; D007328:Insulin