title: Can the analysis of BH3-only protein knockout mice clarify the issue of 'direct versus indirect' activation of Bax and Bak?
authors: A
authors: A
authors: Villunger
authors: V
authors: V
authors: Labi
authors: P
authors: P
authors: Bouillet
authors: J
authors: J
authors: Adams
authors: A
authors: A
authors: Strasser
mesh_terms: D000818:Animals; D051017:Apoptosis Regulatory Proteins / Q000172:deficiency / Q000235:genetics; D051023:BH3 Interacting Domain Death Agonist Protein / Q000172:deficiency / Q000235:genetics; D045304:Cytochromes c / Q000378:metabolism; D007425:Intracellular Membranes / Q000378:metabolism; D008565:Membrane Proteins / Q000172:deficiency / Q000235:genetics; D051379:Mice; D018345:Mice, Knockout; D008928:Mitochondria / Q000378:metabolism; D055503:Protein Multimerization; D025521:Tumor Suppressor Proteins / Q000172:deficiency / Q000235:genetics; D050998:bcl-2 Homologous Antagonist-Killer Protein / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D051028:bcl-2-Associated X Protein / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*
chemical_list: D051017:Apoptosis Regulatory Proteins; D051023:BH3 Interacting Domain Death Agonist Protein; D008565:Membrane Proteins; D025521:Tumor Suppressor Proteins; D050998:bcl-2 Homologous Antagonist-Killer Protein; D051028:bcl-2-Associated X Protein; D045304:Cytochromes c