title: The effect of 90 day administration of a high dose vitamin B-complex on work stress.
abstract: OBJECTIVE
  Occupational stress is increasing in Western societies and the impact is significant at a personal, organisational and community level. The present study examined for the first time the efficacy of 3 months administration of two forms of high dose vitamin B complex on mood and psychological strain associated with chronic work stress.
  
  
  METHODS
  Sixty participants completed the 3-month, double-blind, randomised, placebo-controlled trial in which personality, work demands, mood, anxiety and strain were assessed.
  
  
  RESULTS
  After individual differences in personality and work demands were statistically controlled, the vitamin B complex treatment groups reported significantly lower personal strain and a reduction in confusion and depressed/dejected mood after 12 weeks. There were no treatment-related changes in other measures of mood and anxiety.
  
  
  CONCLUSIONS
  The results of the study are consistent with two previous studies examining multivitamin supplementation and personal (non-work) feelings of strain and suggestive of significant decreases in the experience of workplace stress after 90 day supplementation of a B multivitamin.
  
  
  CONCLUSIONS
  Given the direct and indirect costs of workplace stress, these findings point to the utility of a cost-effective treatment for the mood and psychological strain effects of occupational stress. These findings may have important personal health, organisational and societal outcomes given the rising cost and incidence of workplace stress.
authors: Centre for Human Psychopharmacology, Swinburne University of Technology, Hawthorn, Victoria, Australia. cstough@swin.edu.au
authors: Con
authors: C
authors: Stough
authors: Andrew
authors: A
authors: Scholey
authors: Jenny
authors: J
authors: Lloyd
authors: Jo
authors: J
authors: Spong
authors: Stephen
authors: S
authors: Myers
authors: Luke A
authors: LA
authors: Downey
mesh_terms: D000328:Adult; D000339:Affect / Q000187:drug effects; D001007:Anxiety / Q000188:drug therapy / Q000209:etiology; D003362:Cost-Benefit Analysis; D003692:Delayed-Action Preparations; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009784:Occupational Diseases / Q000188:drug therapy* / Q000191:economics; D013315:Stress, Psychological / Q000188:drug therapy* / Q000191:economics; D014803:Vitamin B Complex / Q000008:administration & dosage / Q000191:economics / Q000494:pharmacology*
chemical_list: D003692:Delayed-Action Preparations; D014803:Vitamin B Complex