title: Non-invasive evaluation of internal thoracic artery anastomosed to the left anterior descending artery with 320-detector row computed tomography and adenosine thallium-201 myocardial perfusion scintigraphy.
abstract: OBJECTIVE
  We evaluated the relationship between internal thoracic artery (ITA) stenosis anastomosed to the left anterior descending artery (LAD) and the degree of LAD stenosis using 320-detector row computed tomography (320-ADCT) and adenosine thallium-201 myocardial perfusion scintigraphy (Tl-201-MPS).
  
  
  METHODS
  We included 101 patients who underwent coronary artery bypass grafting (CABG) using ITA grafts; 320-ADCT and adenosine Tl-201-MPS were performed 2-3 months after CABG. Clinical parameters, degree of LAD stenosis, and regional myocardial ischemia of the LAD territory were compared between patients without ITA stenosis (Group A) and with ITA stenosis (Group B).
  
  
  RESULTS
  Thirty patients (30%) had ≤75% LAD stenosis, and 9 patients (30%) showed significant ITA stenosis. Regional ischemia was noted in 23 patients (23%). There were no differences in clinical parameters between the 2 groups. Twenty-two patients (24%) in Group A and 8 patients (89%) in Group B had ≤75% LAD stenosis (P <0.002). No Group B patients had regional myocardial ischemia of the LAD territory.
  
  
  CONCLUSIONS
  We concluded that ≤75% LAD stenosis significantly influences ITA stenosis, without associated regional myocardial ischemia of the LAD territory. Non-invasive 320-ADCT and adenosine Tl-201-MPS for ITA evaluation may be useful for long-term follow-up of patients after CABG.
authors: Department of Cardiovascular Surgery, Fujita Health University, Dengakugakubo, Kutukake-cho, Toyoake, Aichi, Japan. ytakagi@fujita-hu.ac.jp
authors: Yasushi
authors: Y
authors: Takagi
authors: Kiyotoshi
authors: K
authors: Akita
authors: Hiroshi
authors: H
authors: Kondo
authors: Michiko
authors: M
authors: Ishida
authors: Kan
authors: K
authors: Kaneko
authors: Masato
authors: M
authors: Sato
authors: Motomi
authors: M
authors: Ando
mesh_terms: D000241:Adenosine; D000368:Aged; D000714:Anastomosis, Surgical; D001026:Coronary Artery Bypass / Q000379:methods*; D003327:Coronary Disease / Q000000981:diagnostic imaging* / Q000601:surgery*; D023921:Coronary Stenosis / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D008297:Male; D008323:Mammary Arteries / Q000637:transplantation*; D017202:Myocardial Ischemia / Q000000981:diagnostic imaging*; D055420:Perfusion Imaging / Q000379:methods*; D011183:Postoperative Complications / Q000000981:diagnostic imaging*; D013794:Thallium Radioisotopes; D014057:Tomography, X-Ray Computed / Q000379:methods*; D016896:Treatment Outcome
chemical_list: D013794:Thallium Radioisotopes; D000241:Adenosine