title: Schistosoma hematobium-associated glomerulopathy.
abstract: Schistosomiasis is the second most devastating tropical parasitic disease worldwide and is responsible for many urological complications. However, glomerular injury is a rare complication mainly described with Schistosoma mansoni. We report a case of membranoproliferative glomerulonephritis (MPGN) associated with Schistosoma hematobium infection in a young Senegalese boy living in a rural area. Clinical presentation was with steroid-resistant with nephrotic syndrome. Renal biopsy showed type 1 MPGN with the presence of S. hematobium eggs surrounded by a gigantocellular granuloma. Despite therapy with antihelminthic and immunosuppressive drugs, evolution was characterized by progression to end-stage renal disease over 1 year. More efforts should be made on the prevention and early detection of schistosomiasis among at-risk populations.
authors: Department of Nephrology, University Hospital Aristide Le Dantec, Dakar, Senegal.
authors: S M
authors: SM
authors: Seck
authors: M L
authors: ML
authors: Sarr
authors: M C
authors: MC
authors: Dial
authors: E F
authors: EF
authors: Ka