title: Contacts with children and young people and adult risk of suffering herpes zoster.
abstract: We carried out a matched case-control study to analyze the possible association between exposure to the children and the risk of suffering herpes-zoster in adulthood. Cases of herpes zoster in immunocompetent healthy patients aged ≥ 25 years seen in the dermatology department of the Sagrado Corazón Hospital in 2007-2008 were matched with four controls. Data were analyzed using conditional logistic regression. 153 cases and 604 matched controls were included. Contacts with children were significantly associated with a reduction in the risk of suffering herpes zoster in adulthood (adjusted OR 0.56 [0.37-0.85]). Herpes-zoster vaccination in immunocompetent people aged ≥ 50 years could counteract the possible negative effects of mass varicella vaccination in childhood on the epidemiology of herpes zoster in adults.
authors: Dermatology Department, Sagrado Corazón Hospital, Barcelona, Spain.
authors: M
authors: M
authors: Salleras
authors: A
authors: A
authors: Domínguez
authors: N
authors: N
authors: Soldevila
authors: A
authors: A
authors: Prat
authors: P
authors: P
authors: Garrido
authors: N
authors: N
authors: Torner
authors: E
authors: E
authors: Borrás
authors: L
authors: L
authors: Salleras
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016022:Case-Control Studies; D005260:Female; D006562:Herpes Zoster / Q000453:epidemiology* / Q000276:immunology; D053061:Herpes Zoster Vaccine / Q000008:administration & dosage / Q000276:immunology; D006801:Humans; D008297:Male; D008875:Middle Aged; D018570:Risk Assessment; D013030:Spain / Q000453:epidemiology
chemical_list: D053061:Herpes Zoster Vaccine