title: Novel use of endoluminal repair as prophylaxis of aortic rupture secondary to radiotherapy for lung cancer.
abstract: Non-small-cell lung cancer (NSCLC) invading the aorta is staged as T(4). Only 9% of T(4) tumors are resected; the alternative is chemoradiotherapy, but for peri-aortic NSCLC, radiation damage to the aortic wall can induce fatal rupture. We report the case of a 76 year-old man with a 3-cm left lower lobe NSCLC clearly invading the aortic wall. A thoracic stent graft was inserted prophylactically to prevent aortic rupture. He then received 64 Gy radiotherapy in 32 fractions, resulting in tumor shrinkage. Prophylactic aortic endografting, a less invasive treatment than open surgery, may enable high dose irradiation of the aortic wall.
authors: King's Health Partners Vascular Unit, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom.
authors: Camus
authors: C
authors: Nimmo
authors: Oliver
authors: O
authors: Lyons
authors: Rachel
authors: R
authors: Clough
authors: David
authors: D
authors: Landau
authors: Tom
authors: T
authors: Routledge
authors: Peter
authors: P
authors: Taylor
mesh_terms: D017130:Angioplasty; D001019:Aortic Rupture / Q000209:etiology / Q000517:prevention & control*; D019917:Blood Vessel Prosthesis Implantation; D002289:Carcinoma, Non-Small-Cell Lung / Q000473:pathology / Q000532:radiotherapy*; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology / Q000532:radiotherapy*; D008297:Male; D008875:Middle Aged; D015607:Stents