title: Successful management of descending necrotizing mediastinitis.
abstract: Descending necrotizing mediastinitis is a critical infection and the mortality rate remains high. Early aggressive surgical drainage and antibiotic therapy are essential for treatment. We evaluated the efficiency of transthoracic drainage using a minimally invasive technique in 11 cases of descending necrotizing mediastinitis between May 2002 and March 2008. We performed a right-side minithoracotomy with thoracoscopic assistance, and the mediastinum was thoroughly drained. The length of hospitalization ranged from 30 to 117 days. The postoperative course was good in all patients, and the outcome was favorable. All patients were discharged without major complications. We recommend employing a minithoracotomy with thoracoscopic assistance for aggressive treatment of descending necrotizing mediastinitis.
authors: Division of Thoracic Surgery, Kobe University Graduate School of Medicine, Kobe, Japan.
authors: Teppei
authors: T
authors: Wakahara
authors: Yugo
authors: Y
authors: Tanaka
authors: Yoshimasa
authors: Y
authors: Maniwa
authors: Wataru
authors: W
authors: Nishio
authors: Masahiro
authors: M
authors: Yoshimura
mesh_terms: D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D003646:Debridement; D004322:Drainage / Q000009:adverse effects / Q000379:methods*; D005260:Female; D006801:Humans; D007564:Japan; D007902:Length of Stay; D008297:Male; D008480:Mediastinitis / Q000382:microbiology / Q000473:pathology / Q000601:surgery*; D008875:Middle Aged; D009336:Necrosis; D018579:Patient Selection; D007507:Therapeutic Irrigation; D013906:Thoracoscopy / Q000009:adverse effects; D013908:Thoracotomy / Q000009:adverse effects; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents