title: [Diagnostic and treatment of leg ulcers].
abstract: Ulcers are a frequent cause of dermatologic consultation, and most correspond to leg ulcers. Major advances in the treatment of ulcers have occurred in recent years as a result of research that has led to new concepts such as the consideration of the chronic ulcer as an inflammatory process involving proinflammatory cytokines and deficits of growth factors. Furthermore, studies into the use of the wet dressing have led to the appearance of a wide variety of new dressings. The aim of this review is to update the reader's knowledge of the treatment of ulcers in general and of leg ulcers in particular, with a detailed description of the new dressings available and of the new therapies for use in refractory cases.
authors: Servicio de Dermatología, Hospital Arnau de Vilanova, Valencia, España. m.velasco@arrakis.es
authors: M
authors: M
authors: Velasco
mesh_terms: D000465:Algorithms; D055109:Ankle Brachial Index; D000891:Anti-Infective Agents, Local / Q000627:therapeutic use; D001458:Bandages; D001706:Biopsy; D003131:Combined Modality Therapy; D016207:Cytokines / Q000502:physiology; D003646:Debridement; D003937:Diagnosis, Differential; D016326:Extracellular Matrix Proteins / Q000502:physiology; D006801:Humans; D020100:Hydrogels; D007249:Inflammation; D036341:Intercellular Signaling Peptides and Proteins / Q000502:physiology; D007871:Leg Ulcer / Q000145:classification / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology / Q000503:physiopathology / Q000628:therapy*; D058729:Peripheral Arterial Disease / Q000150:complications / Q000175:diagnosis; D012878:Skin Neoplasms / Q000150:complications / Q000175:diagnosis; D014463:Ultrasonography; D014647:Varicose Ulcer / Q000175:diagnosis / Q000000981:diagnostic imaging; D014945:Wound Healing; D014946:Wound Infection / Q000517:prevention & control
chemical_list: D000891:Anti-Infective Agents, Local; D016207:Cytokines; D016326:Extracellular Matrix Proteins; D020100:Hydrogels; D036341:Intercellular Signaling Peptides and Proteins