title: Palladium-catalyzed 1,4-addition of diarylphosphines to α,β-unsaturated N-acylpyrroles.
abstract: Highly stereoselective asymmetric 1,4-addition of diarylphosphines to α,β-unsaturated N-acylpyrroles catalyzed by a PCP pincer-Pd complex has been developed for the synthesis of chiral phosphines with excellent stereoselectivity (91-99% ee) under mild conditions. The products obtained can be further converted into chiral phosphine-oxazoline ligands.
authors: School of Chemistry & Molecular Engineering, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, China.
authors: Dan
authors: D
authors: Du
authors: Wei-Liang
authors: WL
authors: Duan