title: Evaluation of medetomidine, ketamine and buprenorphine for neutering feral cats.
abstract: A combination of medetomidine (M, 100 μg/kg), ketamine (K, 10 mg/kg) and buprenorphine (B, 10 μg/kg), administered by intramuscular injection, was evaluated for spaying and castration (neutering) of feral cats (n = 101). Eleven animals (11%) required supplemental anesthesia (isoflurane by mask) to maintain an adequate plane of surgical anesthesia. Atipamezole (A, 125 μg/kg) was administered subcutaneously at the completion of surgery. All cats recovered from surgery and were released the following day. A hemoglobin saturation (SpO(2)) value of < 95% was recorded at least once during anesthesia in all cats. This MKB combination can be used in a feral cat sterilization clinic, but isoflurane supplementation may be necessary. Further research is indicated to determine the clinical significance of the low SpO(2) values associated with this anesthetic regimen.
authors: Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL 32610-0136, USA.
authors: Kelly A
authors: KA
authors: Harrison
authors: Sheilah A
authors: SA
authors: Robertson
authors: Julie K
authors: JK
authors: Levy
authors: Natalie M
authors: NM
authors: Isaza
mesh_terms: D000768:Anesthesia, General / Q000662:veterinary*; D019162:Anesthetics, Combined / Q000008:administration & dosage*; D000818:Animals; D000835:Animals, Wild; D001784:Blood Gas Analysis / Q000662:veterinary; D001794:Blood Pressure; D002047:Buprenorphine / Q000008:administration & dosage; D002369:Castration / Q000662:veterinary*; D002415:Cats / Q000601:surgery*; D005260:Female; D006339:Heart Rate; D007649:Ketamine / Q000008:administration & dosage; D008297:Male; D020926:Medetomidine / Q000008:administration & dosage
chemical_list: D019162:Anesthetics, Combined; D002047:Buprenorphine; D007649:Ketamine; D020926:Medetomidine