title: Circulation of diverse genotypes of Tahyna virus in Xinjiang, People's Republic of China.
abstract: Tahyna virus (TAHV) is widely distributed in Europe and Asia. A previous study reported a high level of conservation of the TAHV genome in isolates from Europe. During 2006 and 2007, three Tahyna virus isolates from mosquitoes were obtained from various locations in Xinjiang, People's Republic of China. We analyzed the complete coding sequence of full-length small, medium, and large segments of these isolates. Molecular and phylogenetic analyses of the three complete TAHV genomes showed that sequence identity between isolates from China and Europe was more divergent, and an unexpected level of medium segment diversity was found among isolates from China compared with high levels of sequence conservation for the small and large segments. This study indicated that effects of genotypic diversity on the ecology, transmission, and pathogenicity of TAHV in China should be studied.
authors: State Key Laboratory for Infectious Disease Prevention and Control, Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
authors: Zhi
authors: Z
authors: Lu
authors: Shi-Hong
authors: SH
authors: Fu
authors: Feng-Tian
authors: FT
authors: Wang
authors: Roger S
authors: RS
authors: Nasci
authors: Qing
authors: Q
authors: Tang
authors: Guo-Dong
authors: GD
authors: Liang
mesh_terms: D002681:China / Q000453:epidemiology; D002141:Encephalitis Virus, California / Q000235:genetics*; D004670:Encephalitis, California / Q000453:epidemiology / Q000821:virology*; D014644:Genetic Variation; D005838:Genotype; D010802:Phylogeny