title: Responsive two-photon induced europium emission as fluorescent indicator for paralytic shellfish saxitoxin.
abstract: A water-soluble europium(III) complex (1) has been synthesized and demonstrated to be a specific fluorescence probe for the paralytic shellfish toxin saxitoxin, a neurotoxin that blocks the voltage-gated sodium channels on cell membranes. Saxitoxin binds to the europium complex (K(B) = 6.1 × 10(4) M(-1)) and triggers a two-photon induced f-f emission enhancement by over 100% and increases the two-photon absorption cross-section from 9 to 36 GM.
authors: Laboratory of Chemical Genomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Shenzhen University Town, Xili, Shenzhen 518055, China.
authors: Shuzhong
authors: S
authors: He
authors: Hongguang
authors: H
authors: Li
authors: Yuk-Wang
authors: YW
authors: Yip
authors: Chi-Tung
authors: CT
authors: Yeung
authors: Yuen On
authors: YO
authors: Fung
authors: Hoi-Kuan
authors: HK
authors: Kong
authors: Ho-Lun
authors: HL
authors: Yeung
authors: Ga-Lai
authors: GL
authors: Law
authors: Ka-Leung
authors: KL
authors: Wong
authors: Chi-Sing
authors: CS
authors: Lee
authors: Michael Hon-Wah
authors: MH
authors: Lam
authors: Margaret B
authors: MB
authors: Murphy
authors: Paul Kwan-Sing
authors: PK
authors: Lam
authors: Wing-Tak
authors: WT
authors: Wong
mesh_terms: D000818:Animals; D005063:Europium / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000737:chemistry*; D015394:Molecular Structure; D017785:Photons; D012530:Saxitoxin / Q000737:chemistry*; D012758:Shellfish
chemical_list: D005456:Fluorescent Dyes; D012530:Saxitoxin; D005063:Europium