title: NICE guidance for off-pump CABG: keep the pump primed.
abstract: Because of a desire to reduce the morbidity of a well-established and effective procedure for coronary artery disease, up to 30% of coronary bypass operations are being performed without the use of a heart-lung pump. Concerns remain about the quality of the coronary anastomoses and the completeness of revascularisation. Randomised trials have not disclosed the significant reduction in morbidity or mortality that the early enthusiasts had hoped for. Yet a number of non-randomised studies have shown clinical benefit with the avoidance of an extracorporeal circulation, but these studies have been criticised for potential bias in patient selection and management. Most surgeons have not yet adopted this technique and are waiting for more evidence.
authors: Department of Surgery, Royal Brompton Hospital, Sydney Street, London SW3 6NP, UK. j.pepper@rbht.nhs.uk
authors: John R
authors: JR
authors: Pepper
mesh_terms: D047549:Coronary Artery Bypass, Off-Pump / Q000009:adverse effects / Q000592:standards*; D019317:Evidence-Based Medicine / Q000379:methods / Q000592:standards; D006801:Humans; D017410:Practice Guidelines as Topic; D012196:Review Literature as Topic; D006113:United Kingdom