title: Methods for the preparation of allenes employing indium- and zinc-mediated dehalogenation reactions in aqueous solutions.
abstract: Simple and mild methods for the synthesis of allenes, employing indium- and zinc-mediated dehalogenation reactions of vicinal dihalides in an aqueous solvent, are described. By using these procedures, various allenylmethyl aryl ethers and monosubstituted allenes have been prepared in good to excellent yields.
authors: Department of Chemistry, National Changhua University of Education, Changhua, Taiwan 50007. mhlin@cc.ncue.edu.tw
authors: Mei-Huey
authors: MH
authors: Lin
authors: Wen-Shing
authors: WS
authors: Tsai
authors: Long-Zhi
authors: LZ
authors: Lin
authors: Shiang-Fu
authors: SF
authors: Hung
authors: Tsung-Hsun
authors: TH
authors: Chuang
authors: Yi-Jen
authors: YJ
authors: Su
mesh_terms: D000466:Alkadienes / Q000138:chemical synthesis* / Q000494:pharmacology; D000970:Antineoplastic Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D002384:Catalysis; D002626:Chemistry, Pharmaceutical / Q000379:methods*; D004987:Ethers / Q000138:chemical synthesis* / Q000494:pharmacology; D055772:Green Chemistry Technology; D006219:Halogens / Q000737:chemistry*; D006801:Humans; D007204:Indium / Q000737:chemistry; D015394:Molecular Structure; D009369:Neoplasms / Q000188:drug therapy; D012996:Solutions; D013237:Stereoisomerism; D014867:Water; D015032:Zinc / Q000737:chemistry
chemical_list: D000466:Alkadienes; D000970:Antineoplastic Agents; D004987:Ethers; D006219:Halogens; D012996:Solutions; D007204:Indium; D014867:Water; C025947:propadiene; D015032:Zinc