title: Radiofrequency lesioning for epileptogenic periventricular nodular heterotopia: a rational approach.
abstract: Periventricular nodular heterotopias (PNHs) are frequently associated with pharmacoresistant epilepsy. They are considered part of a dysfunctional network, connected to the overlying cortex. Therefore, removal of the PNHs and additional cortectomy or lobectomy seem to be essential for significant and long-lasting seizure reduction. These procedures, however, can have considerable limitations, especially in patients with functional eloquent cortex adjacent to the PNH. Alternatively, stereotactic neurosurgery can reduce the surgical trauma. Presented is a 56-year-old man who became seizure-free after stereotactically guided radiofrequency lesioning of a solitary PNH.
authors: Department of Neurology, University of Magdeburg, Magdeburg, Germany. fcschmitt@gmx.net
authors: Friedhelm C
authors: FC
authors: Schmitt
authors: Juergen
authors: J
authors: Voges
authors: Lars
authors: L
authors: Buentjen
authors: Friedrich
authors: F
authors: Woermann
authors: Heinz W
authors: HW
authors: Pannek
authors: Martin
authors: M
authors: Skalej
authors: Hans-Jochen
authors: HJ
authors: Heinze
authors: Alois
authors: A
authors: Ebner
mesh_terms: D017115:Catheter Ablation / Q000379:methods*; D004569:Electroencephalography; D004827:Epilepsy / Q000150:complications; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D008875:Middle Aged; D054091:Periventricular Nodular Heterotopia / Q000209:etiology / Q000601:surgery*; D013238:Stereotaxic Techniques