title: Synthesized oversulfated and acetylated derivatives of polysaccharide extracted from Enteromorpha linza and their potential antioxidant activity.
abstract: Sulfated polysaccharide extracted from blue algae Enteromorpha linza is proved to possess excellent antioxidant activities. Two derivatives by means of oversulfated and acetylated coupling were synthesized and investigated their antioxidant activities including scavenging effect of superoxide, hydroxyl and 1,1-diphenyl-2-picrylhydrazyl radicals. And then the relationship between antioxidant activity and chemical characteristics was characterized. The results of chemical analysis and FT-IR showed that the modification of polysaccharide was successful. In addition, it was found that certain derivatives exhibited stronger antioxidant activity than raw material. They could serve as free-radical inhibitors or scavengers, acting possibly as primary antioxidants.
authors: Department of chemistry, Huzhou Teachers College, Huzhou 313000, China. zhzs@hutc.zj.cn
authors: Zhongshan
authors: Z
authors: Zhang
authors: Xiaomei
authors: X
authors: Wang
authors: Shuchi
authors: S
authors: Yu
authors: Li
authors: L
authors: Yin
authors: Mingxing
authors: M
authors: Zhao
authors: Zhiping
authors: Z
authors: Han
mesh_terms: D000107:Acetylation; D001713:Biphenyl Compounds / Q000037:antagonists & inhibitors / Q000378:metabolism; D002626:Chemistry, Pharmaceutical / Q000379:methods*; D016166:Free Radical Scavengers / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D005609:Free Radicals / Q000037:antagonists & inhibitors / Q000378:metabolism; D017665:Hydroxyl Radical / Q000037:antagonists & inhibitors / Q000378:metabolism; D010084:Oxidation-Reduction / Q000187:drug effects; D010851:Picrates / Q000037:antagonists & inhibitors / Q000378:metabolism; D010936:Plant Extracts / Q000737:chemistry*; D011134:Polysaccharides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D012996:Solutions; D017550:Spectroscopy, Fourier Transform Infrared; D013329:Structure-Activity Relationship; D013431:Sulfates / Q000737:chemistry; D013481:Superoxides / Q000037:antagonists & inhibitors / Q000378:metabolism; D044445:Ulva / Q000737:chemistry*
chemical_list: D001713:Biphenyl Compounds; D016166:Free Radical Scavengers; D005609:Free Radicals; D010851:Picrates; D010936:Plant Extracts; D011134:Polysaccharides; D012996:Solutions; D013431:Sulfates; D013481:Superoxides; D017665:Hydroxyl Radical; C004931:1,1-diphenyl-2-picrylhydrazyl