title: ROS signalling of inflammatory cytokines during Trypanosoma cruzi infection.
abstract: Inflammation is a host defence activated by exogenous (e.g. pathogen-derived, pollutants) or endogenous (e.g. reactive oxygen species-ROS) danger signals. Mostly, endogenous molecules (or their derivatives) have well-defined intracellular function but become danger signal when released or exposed following stress or injury. In this review, we discuss the potential role of ROS in chronic evolution of inflammatory cardiovascular diseases, using our experiences working on chagasic cardiomyopathy as a focus-point.
authors: Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, USA.
authors: Shivali
authors: S
authors: Gupta
authors: Monisha
authors: M
authors: Dhiman
authors: Jian-Jun
authors: JJ
authors: Wen
authors: Nisha Jain
authors: NJ
authors: Garg
mesh_terms: D000818:Animals; D002598:Chagas Cardiomyopathy / Q000276:immunology* / Q000473:pathology; D016207:Cytokines / Q000378:metabolism*; D006801:Humans; D007249:Inflammation / Q000276:immunology / Q000473:pathology; D017382:Reactive Oxygen Species / Q000378:metabolism*; D015398:Signal Transduction; D014349:Trypanosoma cruzi / Q000276:immunology* / Q000472:pathogenicity
chemical_list: D016207:Cytokines; D017382:Reactive Oxygen Species