title: FoxO: a new addition to the ESC cartel.
abstract: The forkhead box O (FoxO) family is involved in diverse cellular processes such as tumor suppression, stress response, and metabolism. In a recent Nature Cell Biology Letter, Zhang et al. (2011) uncover a novel role for FoxO proteins in regulating the identity of human ESCs.
authors: Gene Regulation Laboratory, Genome Institute of Singapore, Singapore 138672.
authors: Kevin Andrew Uy
authors: KA
authors: Gonzales
authors: Huck-Hui
authors: HH
authors: Ng
mesh_terms: D000818:Animals; D002453:Cell Cycle; D002470:Cell Survival; D047108:Embryonic Development / Q000235:genetics; D053595:Embryonic Stem Cells / Q000378:metabolism* / Q000473:pathology; D000071161:Forkhead Box Protein O1; D000071316:Forkhead Box Protein O3; D051858:Forkhead Transcription Factors / Q000235:genetics / Q000378:metabolism*; D018507:Gene Expression Regulation, Developmental; D006801:Humans; D051379:Mice; D050814:Octamer Transcription Factor-3 / Q000235:genetics / Q000378:metabolism; D039904:Pluripotent Stem Cells / Q000378:metabolism* / Q000473:pathology; D055748:SOXB1 Transcription Factors / Q000235:genetics / Q000378:metabolism; D013045:Species Specificity
chemical_list: C085126:FOXO1 protein, human; D000071161:Forkhead Box Protein O1; D000071316:Forkhead Box Protein O3; D051858:Forkhead Transcription Factors; C474033:FoxO3 protein, mouse; D050814:Octamer Transcription Factor-3; C494173:POU5F1 protein, human; C527782:SOX2 protein, human; D055748:SOXB1 Transcription Factors