title: [Polymorphic analysis of 5 Y-SNP loci in Han population of Jinan].
abstract: OBJECTIVE
  To investigate polymorphism distribution of the 5 Y-SNP loci in Jinan Han population, and evaluate their potential in forensic application.
  
  
  METHODS
  Genotyping of 5 Y-SNP loci (M89, M9, M122, M134, M95) were executed in the sample of 103 unrelated Chinese male individuals in Jinan Han population by using fragment length discrepant allele specific PCR (FLDAS-PCR).
  
  
  RESULTS
  In 5 Y-SNP loci, genetic polymorphism were identified in Jinan Han population, and the ranges of gene diversity(GD) were 0.093 3-0.491 2. Twenty different haplotypes were observed and the haplotypes diversity (HD) was 0.867 9. Six different haplogroups were detected according to international association of Y chromosome nomenclature.
  
  
  CONCLUSIONS
  Five Y-SNP loci and their haplogroups in Jinan Han population are highly polymorphic, which can provide more information for the genetic structure analysis and forensic genetics research in the region.
authors: Jinan Central Hospital Affiliated to Shandong University, Jinan 250013, China. hanshuyi2007@126.com
authors: Shu-Yi
authors: SY
authors: Han
authors: Hong-Mei
authors: HM
authors: Gao
authors: Mao-Xiu
authors: MX
authors: Zhang
authors: Yan
authors: Y
authors: Zheng
authors: Yan-Fei
authors: YF
authors: Jia
authors: Bu-Tong
authors: BT
authors: Ding
authors: Yun-Shan
authors: YS
authors: Wang
mesh_terms: D000483:Alleles; D044466:Asian People / Q000208:ethnology / Q000235:genetics*; D002681:China / Q000208:ethnology; D041322:Chromosomes, Human, Y / Q000235:genetics*; D053803:Forensic Genetics / Q000379:methods; D005787:Gene Frequency; D005819:Genetic Markers; D006239:Haplotypes; D006801:Humans; D008297:Male; D016133:Polymerase Chain Reaction / Q000379:methods; D020641:Polymorphism, Single Nucleotide / Q000235:genetics*
chemical_list: D005819:Genetic Markers