title: Residues of fluoroquinolones in marine aquaculture environment of the Pearl River Delta, South China.
abstract: Concentrations and distributions of selected fluoroquinolones (norfloxacin, ciprofloxacin and enrofloxacin) in water, sediments and nine kinds of fish species collected from 6 sites in two marine aquaculture regions of the Pearl River Delta, China, were analyzed by using high-performance liquid chromatography with fluorescence detector (HPLC). The results showed that the concentrations of ciprofloxacin and enrofloxacin were below the limits of quantification (LOQ) in all water samples except for norfloxacin. Norfloxacin and ciprofloxacin concentrations ranged from 1.88 to 11.20 ng g(-1) dry wt, 0.76-2.42 ng g(-1) dry wt in sediments collected from the Dapeng'ao region (sites 1-3) and ranged from 2.31 to 4.75 ng g(-1) dry wt, 1.26-1.76 ng g(-1) dry wt in sediments collected from the Hailing Island region (sites 4-6), respectively. However, no enrofloxacin was found in all sediment samples. The three fluoroquinolones (FQs) were detected in all fish samples, and the concentrations were higher in liver tissues than those in muscle tissues. The levels of norfloxacin were higher than ciprofloxacin and enrofloxacin in both liver and muscle tissues. Among the nine marine fish species, Siganus fuscescens from Hailing Island had a significantly high level of norfloxacin in liver tissue (254.58 ng g(-1) wet wt), followed by Sparus macrocephalus (133.15 ng g(-1) wet wt) from Dapeng'ao, and the lowest value was Lutianus argentimaculatus (5.18 ng g(-1) wet wt) from Hailing Island. The obtained results of FQs in present study do not represent a risk to the human health in Guangdong coastal area, based on the maximum residue limits (MRLs) established by Chinese Government and the acceptable daily intake (ADI) recommended by the Food and Agriculture Organization and World Health Organization (FAO/WHO).
authors: Institute of Hydrobiology, Jinan University, Guangzhou, 510632, China.
authors: Xiuting
authors: X
authors: He
authors: Zhaohui
authors: Z
authors: Wang
authors: Xiangping
authors: X
authors: Nie
authors: Yufen
authors: Y
authors: Yang
authors: Debo
authors: D
authors: Pan
authors: Anna O W
authors: AO
authors: Leung
authors: Zhang
authors: Z
authors: Cheng
authors: Yongtao
authors: Y
authors: Yang
authors: Kaibin
authors: K
authors: Li
authors: Kunci
authors: K
authors: Chen
mesh_terms: D000818:Animals; D000890:Anti-Infective Agents / Q000032:analysis* / Q000378:metabolism; D002681:China; D002851:Chromatography, High Pressure Liquid; D002939:Ciprofloxacin / Q000032:analysis* / Q000378:metabolism; D004784:Environmental Monitoring / Q000592:standards; D019015:Geologic Sediments / Q000032:analysis; D006801:Humans; D057230:Limit of Detection; D009643:Norfloxacin / Q000032:analysis* / Q000378:metabolism; D010473:Perciformes / Q000378:metabolism*; D018570:Risk Assessment; D012623:Seawater / Q000032:analysis; D013045:Species Specificity; D014874:Water Pollutants, Chemical / Q000032:analysis* / Q000378:metabolism
chemical_list: D000890:Anti-Infective Agents; D014874:Water Pollutants, Chemical; D002939:Ciprofloxacin; D009643:Norfloxacin