title: Prospective multi-centre study of adjustable single-incision mini-sling (Ajust(®) ) in the management of stress urinary incontinence in women: 1-year follow-up study.
abstract: OBJECTIVE
  To determine whether an adjustable single-incision mini-sling (SIMS, Ajust(®) ) is safe and effective in the management of female stress urinary incontinence (SUI) at 12 months follow-up. To determine whether it is feasible to be performed under local anesthesia (LA).
  
  
  METHODS
  The present study is a multicentre prospective cohort study in which 90 female patients underwent SIMS-Ajust(®) using a standardized insertion technique. The last 45 women were offered the procedure under LA. All patients completed their 12-month follow-up.
  
  
  RESULTS
  The patient-reported success rate, using Patient Global Impression of Improvement (PGI-I), was 80% at 12 months follow-up and a further 6% (n= 5) reported themselves to be 'improved'. In all, 32/45 (71%) patients agreed to undergo the procedure under LA while one patient required conversion to general anaesthetic. There was no organ damage or requirement for blood transfusion. Significantly lower rates of blood loss (P= 0.025) and postoperative voiding difficulties (P= 0.026) were seen in the LA group. The re-operation rate for SUI was 6% at 12 months.
  
  
  CONCLUSIONS
  SIMS (Ajust) appears to be a safe procedure, which is feasible under LA. SIMS (Ajust) have an 80% patient-reported success rate at 12 months follow-up.
authors: Division of Applied Health Sciences, University of Aberdeen, Aberdeen, Scotland. m.abdelfattah@abdn.ac.uk
authors: Mohamed
authors: M
authors: Abdel-Fattah
authors: Wael
authors: W
authors: Agur
authors: Mohamed
authors: M
authors: Abdel-All
authors: Karen
authors: K
authors: Guerrero
authors: Mohamed
authors: M
authors: Allam
authors: Alison
authors: A
authors: Mackintosh
authors: Alyaa
authors: A
authors: Mostafa
authors: Mohamed
authors: M
authors: Yousef
mesh_terms: D000772:Anesthesia, Local; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008875:Middle Aged; D011446:Prospective Studies; D053825:Suburethral Slings; D016896:Treatment Outcome; D014550:Urinary Incontinence, Stress / Q000601:surgery*; D013520:Urologic Surgical Procedures / Q000379:methods*