title: Tissue states provide novel insights into attributes that drive metastasis.
abstract: Recently, in Nature Medicine, Schedin and colleagues define attributes within the involuting postpartum breast microenvironment that promote breast cancer metastasis. Cell invasiveness is controlled by a positive feedback loop involving COX-2 and fibrillar collagen. NSAIDs suppress tumor progression during postpartum involution, potentially providing effective agents for intervention in pregnant women.
authors: Helen Diller Comprehensive Cancer Center, University of California, San Francisco, CA 94143-0511, USA. thea.tlsty@ucsf.edu
authors: Thea D
authors: TD
authors: Tlsty