title: Effect of temporary vocal fold injection medialization on the rate of permanent medialization laryngoplasty in unilateral vocal fold paralysis patients.
abstract: OBJECTIVE
  To determine whether temporary vocal fold injection affects the need for permanent medialization laryngoplasty in patients with unilateral vocal fold paralysis (UVFP).
  
  
  METHODS
  Retrospective chart review.
  
  
  METHODS
  A total of 175 patients with dysphonia resulting from UVFP were identified. Patients with documented recovery of vocal fold mobility, <9 months of follow-up after diagnosis of UVFP, previous treatment at other institutions, neoplastic disease involving the larynx, or history of radiation to the larynx were excluded. Fifty-four patients met all inclusion/exclusion criteria. Rates of permanent medialization laryngoplasty in patients undergoing vocal fold injection were compared with those of patients who chose observation or voice therapy.
  
  
  RESULTS
  A total of 35% of patients underwent temporary injection medialization, and the remaining 65% chose conservative management. Five of 19 of the temporary injection medialization patients subsequently underwent permanent intervention compared to 23 of 35 of the conservative management group (P = .0131).
  
  
  CONCLUSIONS
  UVFP patients who underwent vocal fold injection with an agent intended to provide temporary medialization were statistically significantly less likely to undergo permanent medialization laryngoplasty compared to those patients who were treated with conservative management only.
authors: UCSF Voice and Swallowing Center, University of California, San Francisco, San Francisco, California 94115, USA. kyung@ohns.ucsf.edu
authors: Katherine C
authors: KC
authors: Yung
authors: Ilya
authors: I
authors: Likhterov
authors: Mark S
authors: MS
authors: Courey
mesh_terms: D000328:Adult; D000368:Aged; D001672:Biocompatible Materials / Q000008:administration & dosage; D015331:Cohort Studies; D017886:Durapatite / Q000008:administration & dosage*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015552:Injections, Intralesional; D058753:Laryngoplasty / Q000379:methods*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D018570:Risk Assessment; D012720:Severity of Illness Index; D016896:Treatment Outcome; D014826:Vocal Cord Paralysis / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery*; D014833:Voice Quality
chemical_list: D001672:Biocompatible Materials; D017886:Durapatite