title: Assessing biocomputational modelling in transforming clinical guidelines for osteoporosis management.
abstract: Biocomputational modelling as developed by the European Virtual Physiological Human (VPH) Initiative is the area of ICT most likely to revolutionise in the longer term the practice of medicine. Using the example of osteoporosis management, a socio-economic assessment framework is presented that captures how the transformation of clinical guidelines through VPH models can be evaluated. Applied to the Osteoporotic Virtual Physiological Human Project, a consequent benefit-cost analysis delivers promising results, both methodologically and substantially.
authors: Empirica Communication and Technology Research, Bonn, Germany. rainer.thiel@empirica.com
authors: Rainer
authors: R
authors: Thiel
authors: Marco
authors: M
authors: Viceconti
authors: Karl
authors: K
authors: Stroetmann
mesh_terms: D003198:Computer Simulation; D020000:Decision Support Systems, Clinical; D004470:Economics, Medical; D006291:Health Policy; D006801:Humans; D008490:Medical Informatics / Q000379:methods*; D010024:Osteoporosis / Q000628:therapy*; D017410:Practice Guidelines as Topic; D015203:Reproducibility of Results; D012984:Software; D014584:User-Computer Interface