title: [Fibromyalgia].
abstract: Although chronic musculoskeletal pain represents the main symptom of fibromyalgia, those affected usually experience many and various accompanying symptoms of differing frequency and extent. While symptoms such as non-restful sleep, daytime fatigue, impaired memory and concentration, morning stiffness, as well as digestive and urination disorders help to establish the diagnosis, they represent a particular disease burden on patients, those around them and on the social system. Pathogenetic research is focussed increasingly on a central dysregulation in pain perception and pain processing, leading to the concept of "central sensitisation" as a final common pathway for fibromyalgia and similar syndromes. This supports the recommendations for prompt multimodal therapy based on pharmaco-, functional and behavioural therapy.
authors: Rheumatologische Schwerpunktpraxis München-Gräfelfing, Bahnhofstrasse 95, Gräfelfing, Germany. dr.spaeth@me.com
authors: M
authors: M
authors: Späth
mesh_terms: D002490:Central Nervous System / Q000503:physiopathology; D059333:Central Nervous System Sensitization / Q000502:physiology; D003299:Cooperative Behavior; D003937:Diagnosis, Differential; D003952:Diagnostic Imaging; D005260:Female; D005356:Fibromyalgia / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy; D006801:Humans; D033183:Interdisciplinary Communication; D008297:Male; D017288:Pain Threshold / Q000502:physiology; D010348:Patient Care Team; D012307:Risk Factors