title: Antioxidant and antiacetylcholinesterase activities of some commercial essential oils and their major compounds.
abstract: The commercial essential oils of Citrus aurantium L., Cupressus sempervirens L., Eucalyptus globulus Labill., Foeniculum vulgare Mill. and Thymus vulgaris L., isolated by steam distillation by a company of Morocco were evaluated in terms of in vitro antioxidant activity through several methods. In vitro acetylcholinesterase inhibitory activity was also determined. Citrus limon (L.) Burm. f. oil was also studied, but it was obtained by peel expression. The best antioxidant was T. vulgaris oil, independent of the method used, mainly due to the presence of the phenolic monoterpenes thymol and carvacrol, which when studied as single compounds also presented the best activities. Concerning the acetylcholinesterase inhibition activity, E. globulus was the most effective. Nevertheless its main components 1,8-cineole and limonene were not the most active, a feature that corresponded to d-3-carene.
authors: Laboratory of Physiology-Pharmacology-Environmental Health, Faculty of Sciences Dhar El Mehraz, BP 1796 Atlas, University Sidi Mohamed Ben Abdallah, Fez 30 000, Morocco.
authors: Smail
authors: S
authors: Aazza
authors: Badiâ
authors: B
authors: Lyoussi
authors: Maria G
authors: MG
authors: Miguel
mesh_terms: D000110:Acetylcholinesterase / Q000737:chemistry; D000975:Antioxidants / Q000737:chemistry*; D000081008:Bicyclic Monoterpenes; D001713:Biphenyl Compounds / Q000737:chemistry; D002800:Cholinesterase Inhibitors / Q000737:chemistry*; D003511:Cyclohexanols / Q000737:chemistry; D053138:Cyclohexenes / Q000737:chemistry; D000081007:Cymenes; D057168:Distillation; D057075:Enzyme Assays; D000077591:Eucalyptol; D000077222:Limonene; D015227:Lipid Peroxidation / Q000187:drug effects; D039821:Monoterpenes / Q000737:chemistry; D009822:Oils, Volatile / Q000737:chemistry*; D010084:Oxidation-Reduction; D010851:Picrates / Q000737:chemistry; D010938:Plant Oils / Q000737:chemistry*; D013729:Terpenes / Q000737:chemistry; D017392:Thiobarbituric Acid Reactive Substances / Q000737:chemistry; D013943:Thymol / Q000737:chemistry
chemical_list: D000975:Antioxidants; D000081008:Bicyclic Monoterpenes; D001713:Biphenyl Compounds; D002800:Cholinesterase Inhibitors; D003511:Cyclohexanols; D053138:Cyclohexenes; D000081007:Cymenes; D039821:Monoterpenes; D009822:Oils, Volatile; D010851:Picrates; D010938:Plant Oils; D013729:Terpenes; D017392:Thiobarbituric Acid Reactive Substances; D013943:Thymol; C073316:carvacrol; D000077222:Limonene; C004931:1,1-diphenyl-2-picrylhydrazyl; D000110:Acetylcholinesterase; C030218:3-carene; D000077591:Eucalyptol