title: Demographics of apheresis platelet donors in five blood centers in China.
abstract: BACKGROUND
  Blood component donations by apheresis has become more common in modern blood transfusion practices. However, apheresis donation still remains less common in China. This study describes the demographic profile and transfusion-transmissible infection (TTI) prevalence among donors making apheresis platelet (AP) donations compared to those making whole blood (WB) donations and the differences among five geographically diverse blood centers in China.
  
  
  METHODS
  This is a descriptive study using data from all successful donations at the five blood centers in 2008 and 2009. Donor demographic and TTI screening reactive rates were collected for WB and AP donations and blood centers. Logistic regression was used to identify independent factors associated with AP donations.
  
  
  RESULTS
  From January 1, 2008, to December 31, 2009, there were 512,594 WB and 26,199 AP donations at five blood centers. AP donations accounted for 4.9% of all donations. AP donations have lower reactive rate than WB donations for hepatitis B virus surface antigen, hepatitis C virus antibodies, human immunodeficiency virus antibodies, and syphilis screening testing. Males, donors older than 25 years old, non-Han donors, and donors with below high school educational level were more likely to make AP donations. The characteristics of AP donations differed among the five Chinese blood centers.
  
  
  CONCLUSIONS
  Our analysis suggests that the characteristics of AP donations in China are different from WB donations and differ among the five Chinese blood centers. Some of the differences are likely due to different recruitment policies. Further studies should be conducted to understand what motivates Chinese blood donors to participate as AP donors.
authors: Johns Hopkins Medical Institutions, Baltimore, Maryland 21205, USA. nguo@jhsph.edu
authors: Nan
authors: N
authors: Guo
authors: Jingxing
authors: J
authors: Wang
authors: Paul
authors: P
authors: Ness
authors: Fuzhu
authors: F
authors: Yao
authors: Xiangdong
authors: X
authors: Dong
authors: Xinhong
authors: X
authors: Bi
authors: Heili
authors: H
authors: Mei
authors: Julin
authors: J
authors: Li
authors: Weilan
authors: W
authors: He
authors: Yunlai
authors: Y
authors: Lu
authors: Hongli
authors: H
authors: Ma
authors: Xiuqiong
authors: X
authors: Wen
authors: Mei
authors: M
authors: Huang
authors: Jing
authors: J
authors: Liu
authors: David J
authors: DJ
authors: Wright
authors: Hua
authors: H
authors: Shan
mesh_terms: D000017:ABO Blood-Group System; D000328:Adult; D001771:Blood Banks / Q000706:statistics & numerical data*; D001782:Blood Donors / Q000706:statistics & numerical data*; D002681:China / Q000453:epidemiology; D004522:Educational Status; D005260:Female; D015658:HIV Infections / Q000208:ethnology; D019694:Hepatitis B, Chronic / Q000208:ethnology; D019698:Hepatitis C, Chronic / Q000208:ethnology; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D010983:Plateletpheresis / Q000706:statistics & numerical data*; D015995:Prevalence; D012959:Socioeconomic Factors; D013587:Syphilis / Q000208:ethnology
chemical_list: D000017:ABO Blood-Group System