title: Factors predicting health-related quality of life in knee osteoarthritis among community-dwelling women in Japan: the Hizen-Oshima study.
abstract: Knee osteoarthritis is the most common chronic joint disorder in elderly people. However, a population-based, longitudinal study on health-related quality of life in knee osteoarthritis has not been conducted in Japan. We studied 333 women aged 50 years and older at baseline, with 8 to 9 years of follow-up. Anteroposterior weight-bearing knee radiographs were obtained at baseline and graded according to the Kellgren-Lawrence criteria. Definite osteoarthritis was defined as Kellgren-Lawrence grade 2 or higher in at least 1 joint. At baseline, all participants were asked if they had knee pain and comorbidities (heart disease, lung disease, stroke, or diabetes mellitus). Height (m), weight (kg), and chair stand time were measured. At follow-up, quality of life in knee osteoarthritis was evaluated using the Japanese Knee Osteoarthritis Measure score. Multiple linear regression analysis showed that age, knee osteoarthritis, knee pain, comorbidity, and increasing chair stand time were independently related to subsequent health-related quality of life. These findings suggest that treating knee osteoarthritis and comorbidities, managing pain, and optimizing lower extremity muscle strength may be effective targets for intervention.
authors: Department of Orthopedic Surgery, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
authors: Takahiro
authors: T
authors: Norimatsu
authors: Makoto
authors: M
authors: Osaki
authors: Masato
authors: M
authors: Tomita
authors: Zhaojia
authors: Z
authors: Ye
authors: Yasuyo
authors: Y
authors: Abe
authors: Sumihisa
authors: S
authors: Honda
authors: Mitsuo
authors: M
authors: Kanagae
authors: Satoshi
authors: S
authors: Mizukami
authors: Noboru
authors: N
authors: Takamura
authors: Yosuke
authors: Y
authors: Kusano
authors: Hiroyuki
authors: H
authors: Shindo
authors: Kiyoshi
authors: K
authors: Aoyagi
mesh_terms: D000203:Activities of Daily Living; D000367:Age Factors; D000368:Aged; D003153:Community Health Services; D005260:Female; D006801:Humans; D057187:Independent Living; D007564:Japan / Q000453:epidemiology; D008019:Life Style; D008137:Longitudinal Studies; D008875:Middle Aged; D020370:Osteoarthritis, Knee / Q000453:epidemiology / Q000523:psychology* / Q000534:rehabilitation*; D011237:Predictive Value of Tests; D015995:Prevalence; D011788:Quality of Life; D012307:Risk Factors; D012720:Severity of Illness Index; D016474:Weight-Bearing