title: Peroxynitrite formation and function in plants.
abstract: Peroxynitrite (ONOO(-)) is a reactive nitrogen species formed when nitric oxide (NO) reacts with the superoxide anion (O(2)(-)). It was first identified as a mediator of cell death in animals but was later shown to act as a positive regulator of cell signaling, mainly through the posttranslational modification of proteins by tyrosine nitration. In plants, peroxynitrite is not involved in NO-mediated cell death and its physiological function is poorly understood. However, it is emerging as a potential signaling molecule during the induction of defense responses against pathogens and this could be mediated by the selective nitration of tyrosine residues in a small number of proteins. In this review we discuss the general role of tyrosine nitration in plants and evaluate recent evidence suggesting that peroxynitrite is an effector of NO-mediated signaling following pathogen infection.
authors: Dipartimento di Biotecnologie, Università degli Studi di Verona, Strada Le Grazie, 15, 37 134 Verona, Italy. elodiegenevieve.vandelle@univr.it
authors: Elodie
authors: E
authors: Vandelle
authors: Massimo
authors: M
authors: Delledonne
mesh_terms: D008954:Models, Biological; D009569:Nitric Oxide / Q000737:chemistry / Q000378:metabolism; D030421:Peroxynitrous Acid / Q000096:biosynthesis*; D010944:Plants / Q000378:metabolism*; D026361:Reactive Nitrogen Species / Q000096:biosynthesis*; D015398:Signal Transduction; D013312:Stress, Physiological
chemical_list: D026361:Reactive Nitrogen Species; D030421:Peroxynitrous Acid; D009569:Nitric Oxide