title: Bilateral rubeosis iridis and rubeotic glaucoma due to peripheral occlusive vasculitis associated with multiple sclerosis.
abstract: Multiple sclerosis is associated with iridocyclitis, intermediate uveitis, retinal periphlebitis, and optic neuritis. The periphlebitis is known to be rarely sight-threatening as a result of the sequelae of retinal neovascularization.
  
  
  METHODS
  This is a rare case of bilateral rubeosis iridis and rubeotic glaucoma in the setting of a branch retinal vein occlusion, widespread peripheral periphlebitis, and angiographic peripheral closure associated with "clinically definite" multiple sclerosis.
  
  
  CONCLUSIONS
  The case illustrates the extreme end of the spectrum of peripheral retinal ischemia and neovascularization associated with demyelinating disease, which can present as rubeotic glaucoma. Such patients require a proactive approach to inflammation, neovascularization, and raised intraocular pressure, including systemic immunosuppression, photocoagulation, and augmented trabeculectomy, respectively. As with other causes of peripheral ischemia, a favorable visual outcome can often be achieved using this strategy.
authors: Ophthalmology Department, Leicester Royal Infirmary , Infirmary Square, Leicester, UK. stove@doctors.org.uk
authors: S J
authors: SJ
authors: Turner
authors: A
authors: A
authors: Dharmasena
authors: J
authors: J
authors: Deane
mesh_terms: D000086:Acetazolamide / Q000627:therapeutic use; D000328:Adult; D015355:Glaucoma, Neovascular / Q000209:etiology* / Q000601:surgery; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007500:Iritis / Q000209:etiology* / Q000601:surgery; D008028:Light Coagulation; D008297:Male; D016685:Mitomycin / Q000627:therapeutic use; D009103:Multiple Sclerosis / Q000150:complications*; D011239:Prednisolone / Q000627:therapeutic use; D015861:Retinal Neovascularization / Q000150:complications* / Q000601:surgery; D012170:Retinal Vein Occlusion / Q000150:complications* / Q000209:etiology; D016896:Treatment Outcome; D014792:Visual Acuity / Q000187:drug effects
chemical_list: D007166:Immunosuppressive Agents; D016685:Mitomycin; D011239:Prednisolone; D000086:Acetazolamide