title: Solitary fibrous tumor of the prostate: a report of two cases.
abstract: We here report two cases of solitary fibrous tumor (SFT) arising in the prostate. Two men, 66 and 69 years old, with urinary tract symptoms were diagnosed with SFT on transrectal needle biopsy and transurethral resection of the prostate, respectively. The tumors were removed by a low anterior resection including tumor, prostate and rectum en bloc and cystoprostatectomy, respectively. Both tumors were well-circumscribed but also showed some infiltration of the prostate glands. They were composed of storiform bundles of bland spindle cells that stained strongly for CD34 and vimentin but negative for muscle markers. Although rare, SFT should be considered as differential diagnosis of spindle cell lesions on prostate biopsies.
authors: Department of Oncology-Pathology, Karolinska Institute, Karolinska University Hospital, Stockholm, Sweden.
authors: Heidi
authors: H
authors: Talvitie
authors: Kristina
authors: K
authors: Aström
authors: Olle
authors: O
authors: Larsson
authors: Jan
authors: J
authors: Ahlén
authors: Anders
authors: A
authors: Bergh
authors: Lars
authors: L
authors: Egevad
mesh_terms: D000368:Aged; D018952:Antigens, CD34 / Q000032:analysis / Q000378:metabolism; D001707:Biopsy, Needle; D003937:Diagnosis, Differential; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D011467:Prostate / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D011471:Prostatic Neoplasms / Q000473:pathology* / Q000601:surgery; D054364:Solitary Fibrous Tumors / Q000473:pathology* / Q000601:surgery; D020728:Transurethral Resection of Prostate; D014746:Vimentin / Q000032:analysis / Q000378:metabolism
chemical_list: D018952:Antigens, CD34; D014746:Vimentin