title: [Efficiency of etoxidol in treating cardiovascular disorders caused by experimental cerebral ischemia].
abstract: A complex pharmacological study of the new cytoprotector drug etoksidol in animals with the disturbances of cerebral blood circulation showed that the intravenous introduction of the drug restores autonomous nomotopic driver of rhythm, conductivity in the atria and atrioventricular connection, and refractoriness of the atrioventricular connection, which were violated a result of sharp cerebral ischemia. The new drug does not suppress the inotropic function of the heart in cats and limits the dimensions of the zone of necrosis in rats with the myocardial infarction on the background of deficiency of the cerebral blood flow.
authors: D S
authors: DS
authors: Blinov
authors: L N
authors: LN
authors: Sernov
authors: E V
authors: EV
authors: Blinova
authors: V P
authors: VP
authors: Balashov
authors: E D
authors: ED
authors: Gogina
authors: L V
authors: LV
authors: Van'kova
authors: S Ia
authors: SIa
authors: Skachilova
authors: A B
authors: AB
authors: Lebedev
authors: L A
authors: LA
authors: Belova
mesh_terms: D000818:Animals; D002545:Brain Ischemia / Q000188:drug therapy* / Q000503:physiopathology; D002339:Carotid Arteries / Q000503:physiopathology / Q000601:surgery; D002415:Cats; D002560:Cerebrovascular Circulation / Q000187:drug effects*; D004195:Disease Models, Animal; D004562:Electrocardiography / Q000187:drug effects; D006439:Hemodynamics / Q000187:drug effects; D007042:Hypoxanthines / Q000008:administration & dosage / Q000627:therapeutic use; D008026:Ligation / Q000009:adverse effects / Q000379:methods; D009200:Myocardial Contraction / Q000187:drug effects; D011725:Pyridines / Q000008:administration & dosage / Q000138:chemical synthesis / Q000627:therapeutic use*; D051381:Rats
chemical_list: D007042:Hypoxanthines; D011725:Pyridines