title: Uterine leiomyoma with amianthoid-like fibers.
abstract: A rare case of a gynecologic type leiomyoma with amianthoid-like fibers is presented. The 6 cm tumor was found in the uterus of a 46-year-old woman. Histologically, it contained a cellular spindle cell population with numerous eosinophilic amianthoid-like fibers. The morphology closely resembled that of palisaded "amianthoid" myofibroblastoma. Immunohistochemically, the lesion showed a smooth muscle phenotype with expression of h-caldesmon, desmin, alpha smooth-muscle actin, and with negativity for CD10 and the S100 protein. The finding of amianthoid-like fibers expands the morphologic spectrum of leiomyomas. It represents one of the overlapping features between leiomyoma and palisaded myofibroblastoma.
authors: Medicyt s. r. o., Laboratory Trencín, Slovak Republic. zamecnikm@seznam.cz
authors: M
authors: M
authors: Zámecník
authors: P
authors: P
authors: Kascák
mesh_terms: D005260:Female; D006801:Humans; D007889:Leiomyoma / Q000473:pathology*; D008875:Middle Aged; D009379:Neoplasms, Muscle Tissue / Q000473:pathology; D014594:Uterine Neoplasms / Q000473:pathology*