title: Syntheses and NMR characterizations of epimeric 4-deoxy-4-fluoro carbohydrates.
abstract: The synthesis and NMR characterizations of 1,2,3,6-tetra-O-benzoyl-4-deoxy-4-fluoro-β-d-galactopyranoside, the 4-deoxy-4-fluoro epimer of an intermediate in the synthesis of a drug substance, needed for use as a potential impurity standard and to confirm the stereoselectivity of a key fluorination step, are described.
authors: Chemical Development, sanofi-aventis US, 1041 Route 202-206, Bridgewater, NJ 08807, USA. w.subotkowski@gmail.com
authors: Witold
authors: W
authors: Subotkowski
authors: Dirk
authors: D
authors: Friedrich
authors: Franz J
authors: FJ
authors: Weiberth
mesh_terms: D002236:Carbohydrate Conformation; D002851:Chromatography, High Pressure Liquid; D005643:Fucose / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy / Q000592:standards*; D012015:Reference Standards; D013237:Stereoisomerism
chemical_list: D005643:Fucose