title: Concise asymmetric total synthesis of 9-epi-sessilifoliamide J.
abstract: A 10-step asymmetric synthesis of 9-epi-sessilifoliamide J (20), together with sessilifoliamide J (6), has been accomplished from the key chiral building block 11 via a threo-selective vinylogous Mannich reaction and a Ley oxidation-SmI(2)-mediated coupling lactonization. The absolute configuration of the natural sessilifoliamide J was established.
authors: Department of Chemistry and Key Laboratory for Chemical Biology of Fujian Province, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen, Fujian 361005, PR China.
authors: Shi-Chuan
authors: SC
authors: Tuo
authors: Jian-Liang
authors: JL
authors: Ye
authors: Ai-E
authors: AE
authors: Wang
authors: Su-Yu
authors: SY
authors: Huang
authors: Pei-Qiang
authors: PQ
authors: Huang
mesh_terms: D006575:Heterocyclic Compounds, 3-Ring / Q000138:chemical synthesis* / Q000737:chemistry; D008958:Models, Molecular; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: C569213:9-epi-sessilifoliamide J; D006575:Heterocyclic Compounds, 3-Ring