title: Vitamin C and fibre consumption from fruits and vegetables improves oxidative stress markers in healthy young adults.
abstract: The aim of the present cross-sectional study was to assess the potential relationships between fruit and vegetable (FV) consumption and some oxidative stress markers in young adults, with particular emphasis on fibre and vitamin C intake. The study enrolled 246 healthy subjects (eighty-eight men and 158 women), with a mean age of 22 (sd 3) years and a mean BMI of 21·9 (sd 2·8) kg/m2. Dietary intake, anthropometry, blood pressure, lifestyle features and blood biochemical data were assessed with validated procedures. Those subjects in the highest tertile (T) of FV consumption ( ≥ 705 g/d) had statistically lower oxidised LDL (ox-LDL) concentrations as well as higher plasma total antioxidant capacity (TAC) and glutathione peroxidase (GPx) activity (P for trend <0·05), after adjusting for sex, age, energy intake, physical activity, smoking, BMI, vitamin supplement use and other confounding factors. Moreover, plasma ox-LDL concentrations showed a decreasing trend and TAC an increasing trend across tertiles of fibre (T3: ≥14 g/d) and vitamin C (T3: ≥150 mg/d) from FV intake, while GPx activity was positively associated with vitamin C intake (P for trend < 0·05). In conclusion, greater FV consumption was independently associated with reduced ox-LDL as well as increased TAC and GPx activity in healthy young adults, with dietary fibre and vitamin C from FV clearly being implicated in this beneficial relationship.
authors: Department of Nutrition, Food Science, Physiology and Toxicology, University of Navarra, C/Irunlarrea 1, 31008 Pamplona, Spain.
authors: Helen Hermana M
authors: HH
authors: Hermsdorff
authors: Kiriaque B F
authors: KB
authors: Barbosa
authors: Ana Carolina P
authors: AC
authors: Volp
authors: Blanca
authors: B
authors: Puchau
authors: Josefina
authors: J
authors: Bressan
authors: M Ángeles
authors: MÁ
authors: Zulet
authors: J Alfredo
authors: JA
authors: Martínez
mesh_terms: D000293:Adolescent; D000328:Adult; D000975:Antioxidants / Q000008:administration & dosage; D001205:Ascorbic Acid / Q000008:administration & dosage*; D015415:Biomarkers / Q000097:blood; D003430:Cross-Sectional Studies; D004043:Dietary Fiber / Q000008:administration & dosage*; D005260:Female; D005638:Fruit; D005979:Glutathione Peroxidase / Q000097:blood; D006801:Humans; D008077:Lipoproteins, LDL / Q000097:blood; D008297:Male; D018384:Oxidative Stress / Q000187:drug effects*; D014675:Vegetables; D055815:Young Adult
chemical_list: D000975:Antioxidants; D015415:Biomarkers; D004043:Dietary Fiber; D008077:Lipoproteins, LDL; C099252:oxidized low density lipoprotein; D005979:Glutathione Peroxidase; D001205:Ascorbic Acid