title: [Allergic bronchopulmonary mycosis due to Schizophyllum commune and Aspergillus fumigatus].
abstract: A 53-year-old man who had been suffering from asthma presented to our hospital because of abnormal shadows detected on a chest X-ray film during a routine medical examination. A biopsy specimen of a mucus plug obtained by bronchoscopy showed fungal hyphae, eosinophils, and Charcot-Leyden crystals, with evidence of lung tissue eosinophilia. Schizophyllum commune and Aspergillus fumigatus were isolated from his sputum, bronchial washing specimens and the mucus plug. We detected specific immunoglobulin E anti-Aspergillus fumigatus responses and precipitating antibodies against Schizophyllum commune and Aspergillus fumigatus, which led to the diagnosis of allergic bronchopulmonary mycosis caused by both fungi. We gave him fluticasone/salmeterol and itraconazole; thereafter, his symptoms of cough and sputum production and his radiological findings all improved.
authors: Department of Respiratory Medicine, Saitama Cardiovascular and Respiratory Center.
authors: Takashi
authors: T
authors: Ishiguro
authors: Noboru
authors: N
authors: Takayanagi
authors: Akemi
authors: A
authors: Saito
authors: Kazuo
authors: K
authors: Akiyama
authors: Megumi
authors: M
authors: Wakayama
authors: Kazutoshi
authors: K
authors: Shibuya
authors: Yoshihiko
authors: Y
authors: Shimizu
authors: Yutaka
authors: Y
authors: Sugita
authors: Katsuhiko
authors: K
authors: Kamei
mesh_terms: D001229:Aspergillosis, Allergic Bronchopulmonary / Q000382:microbiology*; D001232:Aspergillus fumigatus / Q000302:isolation & purification*; D006801:Humans; D055744:Invasive Pulmonary Aspergillosis; D008297:Male; D008875:Middle Aged; D012567:Schizophyllum / Q000302:isolation & purification*