title: A web of imprinting in stem cells.
abstract: Imprinted genes are the prototypical epigenetically regulated genes. On the basis of findings in adult lung stem cells, Zacharek et al. (2011) suggest in this issue of Cell Stem Cell that epigenetic silencing of imprinted genes is a common requirement for maintaining self-renewal in adult stem cell populations.
authors: Epigenetics Programme, The Babraham Institute, Cambridge CB22 3AT, UK. gavin.kelsey@babraham.ac.uk
authors: Gavin
authors: G
authors: Kelsey
mesh_terms: D053687:Adult Stem Cells / Q000378:metabolism*; D000818:Animals; D019941:Cyclin-Dependent Kinase Inhibitor p16 / Q000378:metabolism*; D018507:Gene Expression Regulation, Developmental; D009687:Nuclear Proteins / Q000378:metabolism*; D063150:Polycomb Repressive Complex 1; D011518:Proto-Oncogene Proteins / Q000378:metabolism*; D012097:Repressor Proteins / Q000378:metabolism*; D044786:S-Phase Kinase-Associated Proteins / Q000378:metabolism*
chemical_list: C489421:Bmi1 protein, mouse; D019941:Cyclin-Dependent Kinase Inhibitor p16; D009687:Nuclear Proteins; D011518:Proto-Oncogene Proteins; D012097:Repressor Proteins; D044786:S-Phase Kinase-Associated Proteins; D063150:Polycomb Repressive Complex 1