title: Define baseline levels of segments per beam for intensity-modulated radiation therapy delivery for brain, head and neck, thoracic, abdominal, and prostate applications.
abstract: The purpose of this study was to evaluate the number of segments per beam for intensity-modulated radiation therapy (IMRT) treatments and its effects on the plan quality, treatment delivery time, machine quality assurance, and machine maintenance. We have retrospectively analyzed 24 patients treated with IMRT. Five were selected within each of the following regions: head and neck, thoracic, abdomen, and prostate. Four patients were optimized within the brain region. The clinically treated plans were re-optimized using Philips Pinnacle3 v. 8 with the direct machine parameter optimization algorithm. The number of segments per beam from the treated plan was systematically reduced by 80%, 60%, 40%, and 30%, and the following statistics have been analyzed for plan quality: target min, mean, and max doses; critical structure doses; and integral dose. We have attempted to define the smallest number of segments per beam for IMRT treatment plans. Results indicate that IMRT plans can be delivered with acceptable quality with approximately 3-6 segments per beam for the anatomical regions analyzed. A reduction in the number of segments decreases treatment delivery time, reduces machine wear and tear, and minimizes the amount of time the patient is on the treatment table, which in turn reduces the chances of intrafractional uncertainties.
authors: University of Texas M. D. Anderson Cancer Center, Houston, TX, USA. jsutton@mdanderson.org
authors: Jordan
authors: J
authors: Sutton
authors: David
authors: D
authors: Kabiru
authors: Michael
authors: M
authors: Neu
authors: Lehendrick
authors: L
authors: Turner
authors: Peter
authors: P
authors: Balter
authors: Matthew
authors: M
authors: Palmer
mesh_terms: D000328:Adult; D000368:Aged; D001822:Body Burden; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000532:radiotherapy*; D011829:Radiation Dosage; D011874:Radiometry / Q000379:methods*; D011880:Radiotherapy Planning, Computer-Assisted / Q000379:methods*; D020266:Radiotherapy, Conformal / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D055815:Young Adult