title: Intrapulmonary-located Castleman's disease, which was surgically resected without pulmonary resection.
abstract: Castleman's disease (CD) is a rare disease with unknown aetiology. It is characterised by benign lymph node hyperplasia that may involve all lymph nodes. The most common locations are the mediastinum and abdomen. CD arising from intrapulmonary lymph nodes has been reported in five cases, in the English language literature to date. Tumours in these patients are usually resected during lung surgery. An asymptomatic 29-year-old male patient was evaluated due to a mass lesion with a diameter of 55 mm located in the infrahilar region of the right lung with a high degree of contrast enhancement on thoracic computed tomography (CT). Vascularity of this central lesion was excluded by pulmonary angiography. Thoracotomy was performed due to the inability to obtain a diagnosis with percutaneous fine needle aspiration biopsies. A frozen section examination of the mass revealed a benign lesion, arising from the intrapulmonary lymph nodes and protruding to the lower-lobe parenchyma. The mass was then extracted from the parenchyma. After histopathological evaluation of the mass, CD involving the lymph nodes was diagnosed. CD rarely involves the intrapulmonary lymph nodes. Diagnosis is difficult in these patients, and thoracotomy may be required. After obtaining benign results by mass sampling, limited resection of these masses, while sparing the lung parenchyma, may be possible.
authors: Department of Chest Diseases, Yedikule Chest Diseases and Thoracic Surgery Education and Research Hospital, Istanbul, Turkey. gunluoglugulsah@yahoo.com.tr
authors: Gulsah
authors: G
authors: Gunluoglu
authors: Aysun
authors: A
authors: Olcmen
authors: Sinem Nedime
authors: SN
authors: Sokucu
authors: Hasan
authors: H
authors: Akin
authors: Ibrahim
authors: I
authors: Dincer
mesh_terms: D000328:Adult; D005871:Castleman Disease / Q000175:diagnosis / Q000601:surgery*; D005629:Frozen Sections; D006801:Humans; D033162:Incidental Findings; D008171:Lung Diseases / Q000175:diagnosis / Q000601:surgery*; D008197:Lymph Node Excision; D008297:Male; D013908:Thoracotomy; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome