title: A gram scale synthesis of a multi-13C-labelled anthocyanin, [6,8,10,3',5'-13C5]cyanidin-3-glucoside, for use in oral tracer studies in humans.
abstract: The major dietary anthocyanin, cyanidin-3-glucoside, was prepared on a 4 g scale from three units of diethyl [2-(13)C]malonate and one unit of [1,3-(13)C(2)]acetone, such that five isotope locations were distributed throughout the molecule to provide a penta-(13)C(5)-labelled anthocyanin, [6,8,10,3',5'-(13)C(5)]cyanidin-3-glucoside chloride, for use in human stable-isotope tracer studies.
authors: University of St Andrews, EaStChem School of Chemistry and Centre for Biomolecular Sciences, North Haugh, St Andrews, Fife, KY16 9ST, UK. qz@st-andrews.ac.uk
authors: Qingzhi
authors: Q
authors: Zhang
authors: Nigel P
authors: NP
authors: Botting
authors: Colin
authors: C
authors: Kay
mesh_terms: D000284:Administration, Oral; D000872:Anthocyanins / Q000138:chemical synthesis / Q000737:chemistry* / Q000493:pharmacokinetics; D002247:Carbon Isotopes / Q000737:chemistry; D005960:Glucosides / Q000138:chemical synthesis* / Q000737:chemistry* / Q000493:pharmacokinetics; D006801:Humans; D007553:Isotope Labeling; D013237:Stereoisomerism
chemical_list: D000872:Anthocyanins; D002247:Carbon Isotopes; D005960:Glucosides; C462279:cyanidin-3-O-beta-glucopyranoside