title: Comment on "Additive genetic breeding values correlate with the load of partially deleterious mutations".
abstract: Tomkins et al. (Reports, 14 May 2010, p. 892) reported a strong negative correlation between breeding values and mutational load in cow-pea weevils. Here, I show that this result can be attributed to a statistical artifact. By testing the observed correlation against an incorrect null hypothesis, they find a negative correlation where one does not exist.
authors: Institute of Evolutionary Biology and Environmental Studies, University of Zürich, Winterthurerstrasse 190, CH-8057 Zürich, Switzerland. erik.postma@ieu.uzh.ch
authors: Erik
authors: E
authors: Postma
mesh_terms: D000818:Animals; D001947:Breeding; D001517:Coleoptera / Q000235:genetics* / Q000502:physiology; D003627:Data Interpretation, Statistical; D005260:Female; D017344:Genes, Insect; D056084:Genetic Fitness; D014644:Genetic Variation; D007178:Inbreeding; D008297:Male; D009154:Mutation; D010641:Phenotype; D012098:Reproduction; D012641:Selection, Genetic; D013223:Statistics as Topic