title: UK Renal Registry 13th Annual Report (December 2010): Chapter 9: haemoglobin, ferritin and erythropoietin amongst UK adult dialysis patients in 2009: national and centre-specific analyses.
abstract: BACKGROUND
  The UK Renal Association (RA) and National Institute for Health and Clinical Excellence (NICE) have published Clinical Practice Guidelines which include recommendations for management of anaemia in established renal failure.
  
  
  OBJECTIVE
  To determine the extent to which the guidelines for anaemia management are met in the UK.
  
  
  METHODS
  Quarterly data were obtained regarding haemoglobin (Hb) and factors that influence Hb from renal centres in England, Wales, Northern Ireland (EWNI) and the Scottish Renal Registry for the incident and prevalent renal replacement therapy (RRT) cohorts for 2009.
  
  
  RESULTS
  In the UK, in 2009 55% of patients commenced dialysis therapy with Hb x10.0 g/dl (median Hb 10.2 g/dl). The median Hb of haemodialysis (HD) patients was 11.6 g/dl with an interquartile range (IQR) of 10.6 - 12.4 g/dl. Of HD patients 85% had Hb ≥ 10.0 g/dl. The median Hb of peritoneal dialysis (PD) patients in the UK was 11.7 g/dl (IQR 10.7-12.6 g/dl). Of UK PD patients, 88% had Hb ≥ 10.0 g/dl. The median ferritin in HD patients in EWNI was 441 mg/L (IQR 289-629) and 96% of HD patients had a ferritin ≥ 100 mg/L. The median ferritin in PD patients was 249 mg/L (IQR 142-412) with 86% of PD patients having a ferritin 5100 mg/L. In EWNI the mean Erythropoietin Stimulating Agent (ESA) dose was higher for HD than PD patients (9,507 vs. 6,212 IU/week).
  
  
  CONCLUSIONS
  In 2009, 56% of prevalent HD patients had a Hb ≥ 10.5 and ≤ 12.5 g/dl compared with 54% in 2008 and 53% in 2007. Fifty-four percent of prevalent PD patients had a Hb ≥10.5 and ≤12.5 g/dl compared to 55% in 2008.
authors: UK Renal Registry, Southmead Hospital, Bristol, UK. renalreg@renalreg.com
authors: Julie
authors: J
authors: Gilg
authors: Lynsey
authors: L
authors: Webb
authors: Terry
authors: T
authors: Feest
authors: Damian
authors: D
authors: Fogarty
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000554:Ambulatory Care Facilities / Q000639:trends; D000740:Anemia / Q000453:epidemiology / Q000628:therapy; D000847:Annual Reports as Topic; D015331:Cohort Studies; D004921:Erythropoietin / Q000097:blood* / Q000627:therapeutic use; D005260:Female; D005293:Ferritins / Q000097:blood / Q000627:therapeutic use*; D006454:Hemoglobins / Q000378:metabolism / Q000627:therapeutic use*; D006801:Humans; D007676:Kidney Failure, Chronic / Q000097:blood / Q000453:epidemiology / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D012042:Registries; D006435:Renal Dialysis / Q000379:methods*; D006113:United Kingdom / Q000453:epidemiology; D055815:Young Adult
chemical_list: C554270:EPO protein, human; D006454:Hemoglobins; D004921:Erythropoietin; D005293:Ferritins