title: Asymmetric synthesis of ageliferin.
abstract: We describe herein an asymmetric synthesis of ageliferin. A Mn(III)-mediated oxidative radical cyclization reaction was used as the key step to construct the core skeleton of this pyrrole-imidazole dimer. This approach resembles the biogenic [4 + 2] dimerization in an intramolecular fashion.
authors: Division of Chemistry, Department of Biochemistry, The University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Dallas, Texas 75390-9038, United States.
authors: Xiao
authors: X
authors: Wang
authors: Zhiqiang
authors: Z
authors: Ma
authors: Jianming
authors: J
authors: Lu
authors: Xianghui
authors: X
authors: Tan
authors: Chuo
authors: C
authors: Chen
mesh_terms: D002384:Catalysis; D007093:Imidazoles / Q000138:chemical synthesis* / Q000737:chemistry; D008345:Manganese / Q000737:chemistry; D010084:Oxidation-Reduction; D011758:Pyrroles / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D007093:Imidazoles; D011758:Pyrroles; C514118:ageliferin; D008345:Manganese