title: Pulmonary histoplasmosis presenting with the reversed halo sign on high-resolution CT scan.
abstract: We describe the case of a 23-year-old man with pulmonary histoplasmosis whose high-resolution CT scan demonstrated the reversed halo sign. We also extensively review the literature about this CT scan sign. The reversed halo sign has been described in a number of diseases, both infectious and noninfectious. However, to our knowledge, this is the first reported case of pulmonary histoplasmosis presenting with this radiologic finding.
authors: Federal University of Rio de Janeiro, Rio de Janeiro, Brazil. Electronic address: edmarchiori@gmail.com.
authors: Edson
authors: E
authors: Marchiori
authors: University Center Serra dos Órgãos, Teresópolis, Rio de Janeiro, Brazil.
authors: Saulo Maia Davila
authors: SMD
authors: Melo
authors: Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
authors: Flávia Gavinho
authors: FG
authors: Vianna
authors: University Center Serra dos Órgãos, Teresópolis, Rio de Janeiro, Brazil.
authors: Bárbara Santana D
authors: BSD
authors: Melo
authors: Federal University of Sergipe, Aracaju, Sergipe, Brazil; University Center Serra dos Órgãos, Teresópolis, Rio de Janeiro, Brazil.
authors: Saulo Santana D
authors: SSD
authors: Melo
authors: Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
authors: Gláucia
authors: G
authors: Zanetti
mesh_terms: D000328:Adult; D000818:Animals; D000935:Antifungal Agents / Q000008:administration & dosage; D002685:Chiroptera; D004781:Environmental Exposure; D006660:Histoplasmosis / Q000000981:diagnostic imaging* / Q000188:drug therapy; D006801:Humans; D007654:Ketoconazole / Q000008:administration & dosage; D008168:Lung / Q000000981:diagnostic imaging; D008172:Lung Diseases, Fungal / Q000000981:diagnostic imaging* / Q000188:drug therapy; D008297:Male; D014057:Tomography, X-Ray Computed / Q000379:methods*
chemical_list: D000935:Antifungal Agents; D007654:Ketoconazole