title: Voltammetric behaviour of antimalarial drug artesunate in solubilized systems.
abstract: The voltammetric behaviour of artesunate is studied at glassy carbon electrode in different buffer systems using square wave, differential pulse and cyclic voltammetric techniques. The peak current is linear with the drug concentration in the range 4.0-40 μg mL(-1) for serum, plasma and urine. The mean percentage recoveries of the drug, urine, plasma and serum samples are 98.6-100.2%. No electroactive interferences from the excipients and endogenous substance could be observed in the pharmaceutical dosage forms and in biological samples.
authors: School of Studies in Chemistry, Jiwaji University, Gwalior (MP) - 474011, India. rajeevjain54@yahoo.co.in
authors: Rajeev
authors: R
authors: Jain
authors: Vikas
mesh_terms: D000962:Antimalarials / Q000097:blood* / Q000652:urine*; D037621:Artemisinins / Q000097:blood* / Q000652:urine*; D000077332:Artesunate; D004563:Electrochemistry / Q000379:methods*; D006801:Humans
chemical_list: D000962:Antimalarials; D037621:Artemisinins; D000077332:Artesunate