title: Autoinductive exponential signal amplification: a diagnostic probe for direct detection of fluoride.
abstract: A new example of an exponential signal amplification strategy for the direct detection of fluoride is demonstrated. The amplification occurred through reaction of fluoride with a responsive chromogenic probe. The probe activity is based on a unique dendritic chain reaction that generates a fluoride anion, which is the analyte of interest, during the disassembly pathway of the dendritic probe. This autoinductive amplification mechanism may be applied for detection of other analytes by coupling activity of a modified probe with that of the fluoride amplifier.
authors: School of Chemistry, Raymond and Beverly Sackler Faculty of Exact Sciences, Tel Aviv University, Tel Aviv 69978, Israel.
authors: Rotem
authors: R
authors: Perry-Feigenbaum
authors: Eran
authors: E
authors: Sella
authors: Doron
authors: D
authors: Shabat
mesh_terms: D001709:Biotechnology; D002384:Catalysis; D002863:Chromogenic Compounds / Q000032:analysis* / Q000737:chemistry*; D004396:Coloring Agents / Q000737:chemistry*; D050091:Dendrimers / Q000032:analysis* / Q000145:classification*; D005459:Fluorides / Q000032:analysis* / Q000737:chemistry*; D015336:Molecular Probe Techniques; D015394:Molecular Structure; D021141:Nucleic Acid Amplification Techniques / Q000379:methods*
chemical_list: D002863:Chromogenic Compounds; D004396:Coloring Agents; D050091:Dendrimers; D005459:Fluorides