title: Outcomes of 25-gauge pars plana vitrectomy in the surgical management of proliferative diabetic retinopathy.
abstract: OBJECTIVE
  To report outcomes and complications of 25-gauge pars plana vitrectomy (PPV) for patients with complications of proliferative diabetic retinopathy (PDR).
  
  
  METHODS
  Retrospective, interventional, consecutive case series of 174 eyes undergoing primary 25-gauge PPV for PDR from 2006 to 2009. Primary outcomes were visual acuity changes and rates of postoperative complications.
  
  
  RESULTS
  Visual acuity improved from 20/187 before to 20/69 after surgery (P < .0001). Postoperative vitreous hemorrhage occurred in 38.7% of eyes and 10.4% of all eyes required another PPV for non-clearing vitreous hemorrhage. Complications included limited choroidal effusion (5.2%), rhegmatogenous retinal detachment (4.6%), hypotony, rubeosis, and ocular hypertension (4.1%), neovascular glaucoma (2.3%), hyphema (1.2%), and phthisis bulbi (0.6%).
  
  
  CONCLUSIONS
  The authors found 25-gauge PPV to be effective for vitreous removal and membrane dissection. The spectrum and frequency of complications were similar to those reported for 20-gauge PPV for PDR. In the surgical management of PDR, 25-gauge PPV is an alternative.
authors: Department of Ophthalmology, University of Cincinnati College of Medicine, Cincinnati, OH 45242, USA.
authors: Scott D
authors: SD
authors: Schoenberger
authors: Daniel M
authors: DM
authors: Miller
authors: Christopher D
authors: CD
authors: Riemann
authors: Robert E
authors: RE
authors: Foster
authors: Robert A
authors: RA
authors: Sisk
authors: Robert K
authors: RK
authors: Hutchins
authors: Michael R
authors: MR
authors: Petersen
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003930:Diabetic Retinopathy / Q000150:complications / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D014792:Visual Acuity; D014821:Vitrectomy / Q000009:adverse effects / Q000379:methods*