title: Synthesis of selenium-containing amino acid analogues and their biological study.
abstract: Synthesis of selenium-containing amino acid analogues is described. These compounds were prepared in a concise and short synthetic route in good yields by nucleophilic substitution reaction of pyridineselenol and quinolineselenol derivatives with N-phthaloylglycyl chloride followed by hydrazinolysis. The newly synthesized compounds were screened against different strains of bacteria and fungi.
authors: Chemistry Department, Faculty of Science, Taif University, 888, Alhawiya, Taif University, Tai, Kingdom of Saudi Arabia. sabdel68@yahoo.co.uk
authors: S H
authors: SH
authors: Abdel-Hafez
authors: H A
authors: HA
authors: Saad
authors: M R E
authors: MR
authors: Aly
mesh_terms: D000596:Amino Acids / Q000138:chemical synthesis* / Q000494:pharmacology; D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D000935:Antifungal Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D005658:Fungi / Q000187:drug effects; D016566:Organoselenium Compounds / Q000138:chemical synthesis* / Q000494:pharmacology
chemical_list: D000596:Amino Acids; D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D016566:Organoselenium Compounds