title: Histopathological evaluation of the effect of intranasal phototherapy on nasal mucosa in rabbits.
abstract: Allergic rhinitis is a high-incidence allergic inflammation of the nasal airways that impacts quality of life. Of the numerous therapies used to treat allergic rhinitis, intranasal phototherapy has emerged as a promising new treatment modality for inflammatory airway disease. Phototherapy is widely used for the treatment of immune-mediated skin diseases because its profound immunosuppressive effect inhibits hypersensitivity reactions in the skin. Intranasal phototherapy using a combination of Ultraviolet-A (UVA) and Ultraviolet-B (UVB) plus Visible light (VIS) has been shown to suppress the clinical symptoms of allergic rhinitis, but limited data regarding its adverse effects on the nasal mucosa currently exists. In this study, we demonstrate that UV displays no harmful effects on the nasal mucosa cells of rabbits following 2 weeks of intranasal phototherapy.
authors: Department of Otorhinolaryngology and Head and Neck Surgery, Izzet Baysal Medicine Faculty of Abant Izzet Baysal University, Bolu, Turkey. tayfunent@yahoo.com
authors: Tayfun
authors: T
authors: Apuhan
authors: Elçin Hakan
authors: EH
authors: Terzi
authors: Aysel
authors: A
authors: Kükner
authors: Uzeyir
authors: U
authors: Gök
mesh_terms: D000818:Animals; D005260:Female; D008027:Light; D009297:Nasal Mucosa / Q000473:pathology*; D010789:Phototherapy; D011817:Rabbits; D012220:Rhinitis / Q000473:pathology / Q000628:therapy; D014466:Ultraviolet Rays