title: Vector competence of Australian mosquitoes for yellow fever virus.
abstract: The vector competence of Australian mosquitoes for yellow fever virus (YFV) was evaluated. Infection and transmission rates in Cairns and Townsville populations of Aedes aegypti and a Brisbane strain of Ae. notoscriptus were not significantly different from a well-characterized YFV-susceptible strain of Ae. aegypti. After exposure to 10⁷·² tissue culture infectious dose (TCID₅₀)/mL of an African strain of YFV, > 70% of Ae. aegypti and Ae. notoscriptus became infected, and > 50% transmitted the virus. When exposed to 10⁶·⁷) TCID₅₀/mL of a South American strain of YFV, the highest infection (64%) and transmission (56%) rates were observed in Ae. notoscriptus. The infection and transmission rates in the Cairns Ae. aegypti were both 24%, and they were 36% and 28%, respectively, for the Townsville population. Because competent vectors are present, the limited number of travelers from endemic areas and strict vaccination requirements will influence whether YFV transmission occurs in Australia.
authors: Public Health Virology, Communicable Diseases Unit, Forensic and Scientific Services, Queensland Health, Coopers Plains, Australia. andrew_hurk@health.qld.gov.au
authors: Andrew F
authors: AF
authors: van den Hurk
authors: Kate
authors: K
authors: McElroy
authors: Alyssa T
authors: AT
authors: Pyke
authors: Charles E
authors: CE
authors: McGee
authors: Sonja
authors: S
authors: Hall-Mendelin
authors: Andrew
authors: A
authors: Day
authors: Peter A
authors: PA
authors: Ryan
authors: Scott A
authors: SA
authors: Ritchie
authors: Dana L
authors: DL
authors: Vanlandingham
authors: Stephen
authors: S
authors: Higgs
mesh_terms: D000330:Aedes / Q000145:classification / Q000821:virology*; D000818:Animals; D001315:Australia; D007303:Insect Vectors / Q000145:classification / Q000821:virology*; D015004:Yellow Fever / Q000635:transmission; D015005:Yellow fever virus / Q000502:physiology*