title: Spontaneous regression of primary lung cancer arising from an emphysematous bulla.
abstract: Bullous emphysema is an important risk factor for lung cancer. Here, we report the case of a 56-year-old man who underwent surgical treatment for primary lung cancer arising from the wall of a bulla. Chest computed tomography (CT) had revealed a nodule arising from the bulla wall. This nodule showed positive uptake of (18)fluorodeoxyglucose (FDG) during positron emission tomography (PET)-CT. However, repeat CT performed after 2 months showed a spontaneous decrease in the tumor size. Exploratory resection revealed non-small cell lung cancer, which was confirmed by the findings of intraoperative frozen-section analysis; therefore, right upper lobectomy and mediastinal lymph node dissection were performed. The postoperative, pathological diagnosis was squamous cell carcinoma arising from the wall of a bulla. From this case, we infer that lung cancer arising from the wall of a bulla may spontaneously regress, and FDG/PET is a useful tool to diagnose lung tumor in patients with pulmonary bullous disease.
authors: Department of Thoracic Surgery, Okayama University Hospital, 2-5-1 Shikatacho, Kita-ku, Okayama, Japan.
authors: Masashi
authors: M
authors: Furukawa
authors: Takahiro
authors: T
authors: Oto
authors: Masaomi
authors: M
authors: Yamane
authors: Shinichi
authors: S
authors: Toyooka
authors: Katsuyuki
authors: K
authors: Kiura
authors: Shinichiro
authors: S
authors: Miyoshi
mesh_terms: D001768:Blister / Q000150:complications*; D002289:Carcinoma, Non-Small-Cell Lung / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D002294:Carcinoma, Squamous Cell / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D019788:Fluorodeoxyglucose F18; D005629:Frozen Sections; D006801:Humans; D008175:Lung Neoplasms / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D008297:Male; D008875:Middle Aged; D064847:Multimodal Imaging; D009365:Neoplasm Regression, Spontaneous; D009367:Neoplasm Staging; D049268:Positron-Emission Tomography; D011237:Predictive Value of Tests; D011656:Pulmonary Emphysema / Q000150:complications*; D019275:Radiopharmaceuticals; D014057:Tomography, X-Ray Computed; D047368:Tumor Burden
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18