title: A review of antimalarial plants used in traditional medicine in communities in Portuguese-speaking countries: Brazil, Mozambique, Cape Verde, Guinea-Bissau, São Tomé and Príncipe and Angola.
abstract: The isolation of bioactive compounds from medicinal plants, based on traditional use or ethnomedical data, is a highly promising potential approach for identifying new and effective antimalarial drug candidates. The purpose of this review was to create a compilation of the phytochemical studies on medicinal plants used to treat malaria in traditional medicine from the Community of Portuguese-Speaking Countries (CPSC): Angola, Brazil, Cape Verde, Guinea-Bissau, Mozambique and São Tomé and Príncipe. In addition, this review aimed to show that there are several medicinal plants popularly used in these countries for which few scientific studies are available. The primary approach compared the antimalarial activity of native species used in each country with its extracts, fractions and isolated substances. In this context, data shown here could be a tool to help researchers from these regions establish a scientific and technical network on the subject for the CPSC where malaria is a public health problem.
authors: Laboratório de Cromatografia, Departamento de Química, Universidade Federal do Amazonas, Manaus, AM, Brasil.
authors: Jefferson Rocha de A
authors: JR
authors: Silva
authors: Aline de S
authors: Ade S
authors: Ramos
authors: Marta
authors: M
authors: Machado
authors: Dominique F
authors: DF
authors: de Moura
authors: Zoraima
authors: Z
authors: Neto
authors: Marilene M
authors: MM
authors: Canto-Cavalheiro
authors: Paula
authors: P
authors: Figueiredo
authors: Virgilio E
authors: VE
authors: do Rosário
authors: Ana Claudia F
authors: AC
authors: Amaral
authors: Dinora
authors: D
authors: Lopes
mesh_terms: D000810:Angola; D000962:Antimalarials / Q000145:classification / Q000302:isolation & purification / Q000627:therapeutic use*; D001266:Atlantic Islands; D001938:Brazil; D055726:Cabo Verde; D006169:Guinea-Bissau; D006801:Humans; D007802:Language; D008288:Malaria / Q000188:drug therapy*; D008519:Medicine, Traditional; D009073:Mozambique; D008517:Phytotherapy / Q000379:methods*; D010946:Plants, Medicinal / Q000145:classification*
chemical_list: D000962:Antimalarials