title: [The determination of content of circulating CD32+CD40+ micro particles: the modification of method of assessment of destruction of endothelial cells].
abstract: The purpose of study was to develop and test the method of determination of destruction of endotheliocytes in blood-vascular system. The level of circulating endothelial cells was determined by enumeration of CD32+CD40+ micro particles by means of flow cytofluorometry. During the application of the modified method it is demonstrated that in patients with metabolic syndrome the amount of CD32+CD40+ micro particles is twice higher than in the control group (p < 0.05). The research data revealed the increase of content of big endothelin and atherogenic lipoproteids. The method of determination of the level of circulating CD32+CD40+ micro particles can be applied to assess the desquamationed endotheliocytes.
authors: N L
authors: NL
authors: Kutsenko
authors: L G
authors: LG
authors: Savchenko
authors: E I
authors: EI
authors: Kaĭdasheva
authors: L A
authors: LA
authors: Kutsenko
authors: I L
authors: IL
authors: Solokhina
authors: I P
authors: IP
authors: Kaĭdashev
mesh_terms: D000368:Aged; D019013:CD40 Antigens / Q000097:blood*; D055252:Cell-Derived Microparticles / Q000378:metabolism*; D042783:Endothelial Cells / Q000276:immunology / Q000378:metabolism*; D019332:Endothelin-1 / Q000097:blood; D004730:Endothelium, Vascular / Q000166:cytology / Q000503:physiopathology; D005434:Flow Cytometry / Q000379:methods; D006801:Humans; D008297:Male; D024821:Metabolic Syndrome / Q000473:pathology; D008875:Middle Aged; D017452:Receptors, IgG / Q000097:blood*
chemical_list: D019013:CD40 Antigens; D019332:Endothelin-1; D017452:Receptors, IgG