title: Epidemiologic Study of Malassezia Yeasts in Acne Patients by Analysis of 26S rDNA PCR-RFLP.
abstract: BACKGROUND
  Although acne is a common follicular inflammatory dermatosis, studies of the relationship between Malassezia yeasts and acne have rarely been conducted.
  
  
  OBJECTIVE
  We sought to identify Malassezia yeasts from acne patients and establish a relationship between specific types of species of Malassezia and acne.
  
  
  METHODS
  Sixty acne patients were enrolled. Each strain obtained was identified as one of eleven species by 26S rDNA PCR-RFLP. We then compared these data with those of age- and sex-matched healthy subjects.
  
  
  RESULTS
  Growth of Malassezia was evident in fewer patients with acne (50%) in comparison to controls (70.6%). M. restricta was dominant in patients with acne (23.9%), whereas M. globosa was most common (26.7%) in healthy controls. In the patients group, the rate was the highest (71.7%) in the twenties and, in terms of body site, the rate was the highest (60%) in the chest. In the control group, the rate was the highest (75.0%) in the thirties and in the forehead (85.0%).
  
  
  CONCLUSIONS
  The detection rate of Malassezia yeasts was conspicuously low in the acne patients group. Statistically significant differences were observed between the patient and the control groups in the twenties and thirties, and in terms of body site, in the forehead and chest.
authors: Department of Dermatology, Konkuk University School of Medicine, Seoul, Korea.
authors: Young Chan
authors: YC
authors: Song
authors: Hyung Jin
authors: HJ
authors: Hahn
authors: Ji Young
authors: JY
authors: Kim
authors: Jong Hyun
authors: JH
authors: Ko
authors: Yang Won
authors: YW
authors: Lee
authors: Yong Beom
authors: YB
authors: Choe
authors: Kyu Joong
authors: KJ
authors: Ahn