title: Click-chemistry approach to isoxazole-containing α-CF3-substituted α-aminocarboxylates and α-aminophosphonates.
abstract: A convenient strategy for the synthesis of isoxazole-containing α-CF(3)-substituted α-aminocarboxylates and α-aminophosphonates have been developed. The method is based on copper-catalyzed 1,3-dipolar cycloaddition of different aromatic nitrile oxides to functionalized acetylenes.
authors: A.N. Nesmeyanov Institute of Organoelement compounds, Russian Academy of Sciences, 119991, Moscow, Russia. vorobyeva-daria@yandex.ru
authors: Daria V
authors: DV
authors: Vorobyeva
authors: Natalya M
authors: NM
authors: Karimova
authors: Irina L
authors: IL
authors: Odinets
authors: Gerd-Volker
authors: GV
authors: Röschenthaler
authors: Sergey N
authors: SN
authors: Osipov
mesh_terms: D002264:Carboxylic Acids / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D057930:Click Chemistry; D003300:Copper / Q000737:chemistry; D003500:Cyclization; D006845:Hydrocarbons, Fluorinated / Q000737:chemistry*; D007555:Isoxazoles / Q000737:chemistry*; D015394:Molecular Structure; D063065:Organophosphonates / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D002264:Carboxylic Acids; D006845:Hydrocarbons, Fluorinated; D007555:Isoxazoles; D063065:Organophosphonates; D003300:Copper