title: [Placing of oral implants in patients using bisphosphonates].
abstract: Dentists are with increasing frequency confronted with patients who are being treated with bisphosphonates for certain bone diseases, hypercalcaemia, and bone metastases of solid malignancies. A side effect of the use of bisphosphonates is osteonecrosis of the jaw. Bisphosphonate-induced osteonecrosis of the jaw occurs mainly after treatment with intravenous bisphosphonates and to a much lesser extent after oral administration of bisphosphonates. The question remains whether oral implants can be safely placed in patients using bisphosphonates. A survey of the literature shows that the risk ofosteonecrosis of the jaw and loss of oral implants is not increased when the implants are placed within 3 years after starting treatment with oral bisphosphonates. After this period there is the possibility of a slightly increased risk of complications. The possibility of complications is higher in patients receiving the intravenous bisphosphonates, and, therefore, elective surgical treatments is not advocated.
authors: Afdeling Mondziekten, Kaak- en Aangezichtschirurgie, Medisch Centrum Leeuwarden, Leeuwarden.
authors: K H E
authors: KH
authors: Verbruggen
authors: J G A M
authors: JG
authors: de Visscher
mesh_terms: D050071:Bone Density Conservation Agents / Q000009:adverse effects*; D003758:Dental Implantation, Endosseous; D019232:Dental Restoration Failure; D004164:Diphosphonates / Q000009:adverse effects*; D006801:Humans; D007571:Jaw Diseases / Q000139:chemically induced*; D008334:Mandible / Q000601:surgery; D008437:Maxilla / Q000601:surgery; D010020:Osteonecrosis / Q000139:chemically induced*; D012307:Risk Factors; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D050071:Bone Density Conservation Agents; D004164:Diphosphonates