title: Vertebral bone metastasis in breast cancer: a case report.
abstract: BACKGROUND
  We report here a case of a 66-year-old woman with a very aggressive form of breast carcinoma, having both liver and bone dissemination points.
  
  
  METHODS
  The patient was admitted for a rapid onset disk-herniation-like syndrome, but which on further investigation proved to be in fact a metastatic case of breast cancer. We found evidence of disseminations at least in the lumbar vertebral bodies and the liver. Pathological analysis of the available vertebral metastasis revealed a HER2+ molecular pattern, accordingly to the newly evolving molecular typing of breast cancers. Despite a rapid treatment instauration, the patient reacted poorly to taxanes and octeoclast inhibitors, and died after less than 11 months from admitting to the hospital.
  
  
  CONCLUSIONS
  This is a rare case of an aggressive breast carcinoma identified initially after the vertebral metastases themselves that induced a non-specific symptomatology.
authors: Department of Oncology, Emergency County Hospital Valcea, Ramnicu Valcea, Romania. daniel.pirici@webmail.umfcv.ro
authors: Elena
authors: E
authors: Pirici
authors: A
authors: A
authors: Pirici
authors: Nicoleta
authors: N
authors: Pătrană
authors: Felicia
authors: F
authors: Recăreanu
authors: Fl
authors: F
authors: Bădulescu
authors: Anda Elena
authors: AE
authors: Crişan
authors: Ana Sorina
authors: AS
authors: Zaharie
mesh_terms: D000368:Aged; D001859:Bone Neoplasms / Q000556:secondary*; D001943:Breast Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans; D008159:Lumbar Vertebrae / Q000473:pathology*