title: Preparation of photoresponsive DNA tethering ortho-methylated azobenzene as a supra-photoswitch.
abstract: This unit describes synthetic procedures of photoresponsive DNA via a phosphoramidite monomer composed of D-threoninol as a scaffold and 4-carboxy-2',6'-dimethylazobenzene or 4-carboxy-2'-methylazobenzene that works as a photoswitch more efficiently than previous nonmodified azobenzene (4-phenylazobenzoic acid). With these newly modified-azobenzenes, photoregulatory efficiency of DNA hybridization can be greatly improved. Furthermore, thermal stability of cis-azobenzene of 4-carboxy-2',6'-dimethylazobenzene remarkably increases compared with the previous non-modified azobenzene.
authors: Nagoya University, Nagoya, Japan.
authors: Hiroyuki
authors: H
authors: Asanuma
authors: Hidenori
authors: H
authors: Nishioka
authors: Teruchika
authors: T
authors: Ishikawa
authors: Xingguo
authors: X
authors: Liang
mesh_terms: D000605:Amino Alcohols / Q000737:chemistry; D001391:Azo Compounds / Q000737:chemistry; D002072:Butylene Glycols / Q000737:chemistry; D004247:DNA / Q000737:chemistry*; D010777:Photochemistry / Q000379:methods*
chemical_list: D000605:Amino Alcohols; D001391:Azo Compounds; D002072:Butylene Glycols; C532652:threoninol; D004247:DNA; C009850:azobenzene