title: Organocatalytic asymmetric intermolecular dehydrogenative α-alkylation of aldehydes using molecular oxygen as oxidant.
abstract: An organocatalytic enantioselective intermolecular oxidative dehydrogenative α-alkylation of aldehydes via benzylic C-H bond activation has been developed. The asymmetric reaction is smoothly fulfilled by using simple and green molecular oxygen as the oxidant. Two hydrogen dissociations make this transformation more environmentally benign because of high atom efficiency.
authors: State Key Laboratory of Natural and Biomimetic Drugs, Peking University, School of Pharmaceutical Sciences, Peking University, Xue Yuan Road 38, Beijing 100191, China.
authors: Bo
authors: B
authors: Zhang
authors: Shi-Kai
authors: SK
authors: Xiang
authors: Li He
authors: LH
authors: Zhang
authors: Yuxin
authors: Y
authors: Cui
authors: Ning
authors: N
authors: Jiao
mesh_terms: D000447:Aldehydes / Q000737:chemistry*; D000478:Alkylation; D002384:Catalysis; D006859:Hydrogen / Q000737:chemistry*; D015394:Molecular Structure; D016877:Oxidants / Q000737:chemistry*; D010100:Oxygen / Q000737:chemistry*; D013237:Stereoisomerism; D014966:Xanthenes / Q000737:chemistry
chemical_list: D000447:Aldehydes; D016877:Oxidants; D014966:Xanthenes; D006859:Hydrogen; D010100:Oxygen