title: A graphene oxide-peptide fluorescence sensor tailor-made for simple and sensitive detection of matrix metalloproteinase 2.
abstract: A graphene oxide-peptide based fluorescence sensor has been developed for matrix metalloproteinase 2 (MMP2), and its applicability has been demonstrated by monitoring the concentration of MMP2 secreted by HeLa cells, revealing that HeLa cells with a density of 5.48 × 10(5) cells per mL can produce 22 nM in cell culture media in 24 h.
authors: Beijing National Laboratory for Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China.
authors: Duan
authors: D
authors: Feng
authors: Yangyang
authors: Y
authors: Zhang
authors: Tingting
authors: T
authors: Feng
authors: Wen
authors: W
authors: Shi
authors: Xiaohua
authors: X
authors: Li
authors: Huimin
authors: H
authors: Ma
mesh_terms: D005456:Fluorescent Dyes / Q000737:chemistry; D006108:Graphite / Q000737:chemistry*; D006367:HeLa Cells; D006801:Humans; D020778:Matrix Metalloproteinase 2 / Q000032:analysis*; D010087:Oxides / Q000737:chemistry*; D010455:Peptides / Q000737:chemistry*; D010618:Phenanthrolines / Q000737:chemistry; D013050:Spectrometry, Fluorescence / Q000379:methods*
chemical_list: D005456:Fluorescent Dyes; D010087:Oxides; D010455:Peptides; D010618:Phenanthrolines; D006108:Graphite; D020778:Matrix Metalloproteinase 2; C025205:1,10-phenanthroline