title: Weight loss and severe jaundice in a patient with hyperthyroidism.
abstract: BACKGROUND
  Thyrotoxicosis may significantly alter hepatic function and is associated with autoimmune disorders of the liver.
  
  
  METHODS
  We report the case of a thyrotoxic patient with Graves' disease and histologically established cholestatic hepatitis. Medical treatment of hyperthyroidism normalized liver function tests.
  
  
  CONCLUSIONS
  In patients with elevated liver function parameters and jaundice of unknown origin, thyroid function should generally be tested. Moreover, medical treatment of hyperthyroidism with thyrostatics may cause severe hepatitis whereas untreated hyperthyroid patients are at risk of developing chronic liver failure.
authors: Department of Internal Medicine I, District Hospital Clinic Altmühltal, Kösching, Germany. Matthias.Breidert@klinikkoesching.de
authors: M
authors: M
authors: Breidert
authors: S
authors: S
authors: Offensperger
authors: H E
authors: HE
authors: Blum
authors: R
authors: R
authors: Fischer
mesh_terms: D006111:Graves Disease / Q000150:complications* / Q000503:physiopathology; D006801:Humans; D041781:Jaundice, Obstructive / Q000209:etiology* / Q000503:physiopathology; D008111:Liver Function Tests; D008297:Male; D015431:Weight Loss; D055815:Young Adult