title: [Bone loss in lactating women and post-pregnancy osteoporosis].
abstract: Measurement of the bone mineral density have shown that lactating women had 1 to 3% decrease in bone mineral density. Post pregnancy osteoporosis is rare condition that causes fragile fracture mostly in vertebrae. The bone loss in lactating women is caused by calcium loss, decrease in estrogen level, and increase in PTHrP (parathyroid hormone related protein) level. Some data have shown that extended lactation and amenorrhea had an association with the degree of bone loss. Mostly, the bone loss of the lactating women recovers to the baseline level, soon after the weaning, and there is no long term effect. Post pregnancy osteoporosis should be concerned, when we see a lactating woman with fragile fracture of the vertebrae.
authors: Department of gynecology and obstetrics, Yokohama Rousai Hospital, Japan.
authors: Go
authors: G
authors: Hirata
authors: Osamu
authors: O
authors: Chaki
mesh_terms: D015519:Bone Density; D050071:Bone Density Conservation Agents / Q000008:administration & dosage; D002118:Calcium / Q000172:deficiency; D002136:Calcium, Dietary / Q000008:administration & dosage; D004164:Diphosphonates / Q000008:administration & dosage; D004967:Estrogens / Q000172:deficiency; D005260:Female; D006801:Humans; D007774:Lactation / Q000378:metabolism*; D010024:Osteoporosis / Q000209:etiology* / Q000628:therapy; D058866:Osteoporotic Fractures / Q000209:etiology* / Q000517:prevention & control; D044162:Parathyroid Hormone-Related Protein / Q000378:metabolism; D049590:Postpartum Period / Q000378:metabolism; D011247:Pregnancy; D012307:Risk Factors; D016103:Spinal Fractures / Q000209:etiology*; D014807:Vitamin D / Q000008:administration & dosage
chemical_list: D050071:Bone Density Conservation Agents; D002136:Calcium, Dietary; D004164:Diphosphonates; D004967:Estrogens; D044162:Parathyroid Hormone-Related Protein; D014807:Vitamin D; D002118:Calcium