title: Novel strategies for sample preparation in forensic toxicology.
abstract: This paper provides a review of novel strategies for sample preparation in forensic toxicology. The review initially outlines the principle of each technique, followed by sections addressing each class of abused drugs separately. The novel strategies currently reviewed focus on the preparation of various biological samples for the subsequent determination of opiates, benzodiazepines, amphetamines, cocaine, hallucinogens, tricyclic antidepressants, antipsychotics and cannabinoids. According to our experience, these analytes are the most frequently responsible for intoxications in Greece. The applications of techniques such as disposable pipette extraction, microextraction by packed sorbent, matrix solid-phase dispersion, solid-phase microextraction, polymer monolith microextraction, stir bar sorptive extraction and others, which are rapidly gaining acceptance in the field of toxicology, are currently reviewed.
authors: Laboratory of Analytical Chemistry, Department of Chemistry, Aristotle University of Thessaloniki, Greece. samanidu@chem.auth.gr
authors: Victoria
authors: V
authors: Samanidou
authors: Leda
authors: L
authors: Kovatsi
authors: Domniki
authors: D
authors: Fragou
authors: Konstantinos
authors: K
authors: Rentifis
mesh_terms: D000327:Adsorption; D053593:Forensic Toxicology / Q000379:methods*; D006115:Greece; D006213:Hallucinogens / Q000032:analysis; D006801:Humans; D013287:Illicit Drugs / Q000032:analysis*; D059627:Liquid Phase Microextraction / Q000295:instrumentation / Q000379:methods; D008872:Microwaves; D004364:Pharmaceutical Preparations / Q000032:analysis; D052616:Solid Phase Extraction / Q000295:instrumentation / Q000379:methods; D052617:Solid Phase Microextraction / Q000295:instrumentation / Q000379:methods
chemical_list: D006213:Hallucinogens; D013287:Illicit Drugs; D004364:Pharmaceutical Preparations