title: European expert opinion on the management of invasive candidiasis in adults.
abstract: This report discusses the present status of antifungal therapy and treatment options for candidaemia, considered by experts in the field in Europe. A conference of 26 experts from 13 European countries was held to discuss strategies for the treatment and prevention of invasive candidiasis, with the aim of providing a review on optimal management strategies. Published and unpublished comparative trials on antifungal therapy were analysed and discussed. Commonly asked questions about the management of candidaemia were selected, and possible responses to these questions were discussed. Panellists were then asked to respond to each question by using a touchpad answering system. After the initial conference, the viewpoint document has been reviewed and edited to include new insights and developments since the initial meeting. For many situations, consensus on treatment could not be reached, and the responses indicate that treatment is likely to be modified on a patient-to-patient basis, depending on factors such as degree of illness, prior exposure to azole antifungals, and the presence of potentially antifungal drug-resistant Candida species.
authors: Nijmegen Institute for Infection, Inflammation and Immunity, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands. b.kullberg@aig.umcn.nl
authors: B J
authors: BJ
authors: Kullberg
authors: P E
authors: PE
authors: Verweij
authors: M
authors: M
authors: Akova
authors: M C
authors: MC
authors: Arendrup
authors: J
authors: J
authors: Bille
authors: T
authors: T
authors: Calandra
authors: M
authors: M
authors: Cuenca-Estrella
authors: R
authors: R
authors: Herbrecht
authors: F
authors: F
authors: Jacobs
authors: M
authors: M
authors: Kalin
authors: C C
authors: CC
authors: Kibbler
authors: O
authors: O
authors: Lortholary
authors: P
authors: P
authors: Martino
authors: J F
authors: JF
authors: Meis
authors: P
authors: P
authors: Muñoz
authors: F C
authors: FC
authors: Odds
authors: B E
authors: BE
authors: De Pauw
authors: J H
authors: JH
authors: Rex
authors: E
authors: E
authors: Roilides
authors: T R
authors: TR
authors: Rogers
authors: M
authors: M
authors: Ruhnke
authors: A J
authors: AJ
authors: Ullmann
authors: Ö
authors: Ö
authors: Uzun
authors: K
authors: K
authors: Vandewoude
authors: J-L
authors: JL
authors: Vincent
authors: J P
authors: JP
authors: Donnelly
mesh_terms: D000328:Adult; D019072:Antibiotic Prophylaxis; D000935:Antifungal Agents / Q000627:therapeutic use*; D058365:Candidiasis, Invasive / Q000175:diagnosis / Q000188:drug therapy*; D005060:Europe; D006801:Humans; D007362:Intensive Care Units; D057832:Watchful Waiting
chemical_list: D000935:Antifungal Agents