title: Prevalence and epidemiology of overweight and obesity in children with inflammatory bowel disease.
abstract: BACKGROUND
  Obesity is a significant public health threat to children in the United States. The aims were to: 1) Determine the prevalence of obesity in a multicenter cohort of children with inflammatory bowel disease (IBD); 2) Evaluate whether overweight and obese status is associated with patient demographics or disease characteristics.
  
  
  METHODS
  We used data from the ImproveCareNow Collaborative for pediatric IBD, a multicenter registry of children with IBD, collected between April 2007 and December 2009. Children ages 2-18 years were classified into body mass index (BMI) percentiles. Bivariate analyses and multivariate logistic regression were used to compare demographic and disease characteristics by overweight (BMI >85%) and obese (BMI >95%) status.
  
  
  RESULTS
  The population consisted of 1598 children with IBD. The prevalence of overweight/obese status in pediatric IBD is 23.6%, (20.0% for Crohn's disease [CD] and 30.1% for ulcerative colitis [UC] and indeterminate colitis [IC]). African American race (odds ratio [OR] 1.64, 95% confidence interval [CI] 1.10-2.48) and Medicaid insurance (OR 1.67, 95% CI 1.19-2.34) were positively associated with overweight/obese status. Prior IBD-related surgery (OR 1.73, 95% CI 1.07-2.82) was also associated with overweight and obese status in children with CD. Other disease characteristics were not associated with overweight and obesity in children with IBD.
  
  
  CONCLUSIONS
  Approximately one in five children with CD and one in three with UC are overweight or obese. Rates of obesity in UC are comparable to the general population. Obese IBD patients may have a more severe disease course, as indicated by increased need for surgery. Sociodemographic risk factors for obesity in the IBD population are similar to those in the general population.
authors: University of North Carolina at Chapel Hill, Department of Medicine, Division of Gastroenterology and Hepatology, Chapel Hill, North Carolina 27599-7080, USA. millie_long@med.unc.edu
authors: Millie D
authors: MD
authors: Long
authors: Wallace V
authors: WV
authors: Crandall
authors: Ian H
authors: IH
authors: Leibowitz
authors: Lynn
authors: L
authors: Duffy
authors: Fernando
authors: F
authors: del Rosario
authors: Sandra C
authors: SC
authors: Kim
authors: Mark J
authors: MJ
authors: Integlia
authors: James
authors: J
authors: Berman
authors: John
authors: J
authors: Grunow
authors: Richard B
authors: RB
authors: Colletti
authors: Bess T
authors: BT
authors: Schoen
authors: Ashish S
authors: AS
authors: Patel
authors: Howard
authors: H
authors: Baron
authors: Esther
authors: E
authors: Israel
authors: George
authors: G
authors: Russell
authors: Sabina
authors: S
authors: Ali
authors: Hans H
authors: HH
authors: Herfarth
authors: Christopher
authors: C
authors: Martin
authors: Michael D
authors: MD
authors: Kappelman
mesh_terms: D000293:Adolescent; D015992:Body Mass Index; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D003093:Colitis, Ulcerative / Q000150:complications / Q000453:epidemiology*; D003424:Crohn Disease / Q000150:complications / Q000453:epidemiology*; D003430:Cross-Sectional Studies; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D009765:Obesity / Q000453:epidemiology* / Q000209:etiology; D050177:Overweight / Q000453:epidemiology* / Q000209:etiology; D015995:Prevalence; D011379:Prognosis; D012307:Risk Factors; D014481:United States / Q000453:epidemiology