title: [Topical negative pressure and skin transplantation for the treatment of pyoderma gangrenosum].
abstract: Pyoderma gangrenosum (PG) is a rare idiopathic, autoimmune and inflammatory disease characterized by the development of ulcerative skin lesions. A 58 year-old woman, diagnosed with biopsy-verified PG was admitted to the Wound Center at Odense University Hospital, with rapid progression of painful, necrotic PG lesions on both crura. The lesions were treated, in collaboration with the dermatologists, with systemic steroids, topical negative pressure treatments and surgical revision in addition to partial skin graft with good results. Following the treatment the patient has been pain free and without recurrence for 11 months.
authors: Plastikkirurgisk Afdeling, Odense Universitetshospital, Denmark. roalemana@hotmail.com
authors: Rocío Caballero
authors: RC
authors: Gámiz
authors: Ana Marie
authors: AM
authors: Nielsen
mesh_terms: D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007866:Leg; D008875:Middle Aged; D054843:Negative-Pressure Wound Therapy; D011239:Prednisolone / Q000627:therapeutic use; D017511:Pyoderma Gangrenosum / Q000188:drug therapy / Q000473:pathology / Q000601:surgery / Q000628:therapy*; D016038:Skin Transplantation; D016896:Treatment Outcome
chemical_list: D005938:Glucocorticoids; D011239:Prednisolone