title: Microbiologic findings 1 year after partial- and full-mouth scaling in the treatment of moderate chronic periodontitis.
abstract: OBJECTIVE
  To investigate the impact on microbiologic variables of full-mouth scaling (FMS) and conventional scaling and root planing (cSRP) after 12 months.
  
  
  METHODS
  In a prospective randomized controlled clinical study, 37 volunteers with moderate chronic periodontitis were treated by FMS or by cSRP in two sessions at 4-week intervals. Clinical attachment level, probing depth, and bleeding on probing were recorded at baseline as well as at 6 and 12 months. Four subgingival plaque samples were taken from the deepest sites in premolars and molars at baseline and after 12 months. Pooled sample analysis was performed using real-time polymerase chain reaction for the identification of Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Tannerella forsythia, and Treponema denticola.
  
  
  RESULTS
  At baseline, the bacterial load of A actinomycetemcomitans was significantly higher in the cSRP group compared to the FMS group (P = .042). In the cSRP group, this load decreased significantly (P = .011), leading to similar quantities of A actinomycetemcomitans in both groups. Further, significant reductions in frequency were found in the FMS group for T forsythia and P gingivalis and in the cSRP group for A actinomycetemcomitans and T denticola.
  
  
  CONCLUSIONS
  The data suggest that both therapy modalities lead to similar effects on target periodontal pathogen species. FMS compared to cSRP was not favorable in reduction of periodontopathogens.
authors: Department of Conservative Dentistry and Periodontology, University of Leipzig, Leipzig, Germany. gerhild.knoefler@medizin.uni-leipzig.de
authors: Gerhild U
authors: GU
authors: Knöfler
authors: Regina E
authors: RE
authors: Purschwitz
authors: Sigrun
authors: S
authors: Eick
authors: Wolfgang
authors: W
authors: Pfister
authors: Mirjam
authors: M
authors: Roedel
authors: Holger F R
authors: HF
authors: Jentsch
mesh_terms: D016976:Aggregatibacter actinomycetemcomitans / Q000302:isolation & purification; D058491:Bacterial Load; D001439:Bacteroides / Q000302:isolation & purification; D001641:Bicuspid / Q000382:microbiology; D055113:Chronic Periodontitis / Q000382:microbiology / Q000628:therapy*; D003773:Dental Plaque / Q000382:microbiology; D005260:Female; D005500:Follow-Up Studies; D005884:Gingival Hemorrhage / Q000145:classification / Q000628:therapy; D006090:Gram-Negative Bacteria / Q000302:isolation & purification*; D006801:Humans; D008297:Male; D008875:Middle Aged; D008963:Molar / Q000382:microbiology; D017622:Periodontal Attachment Loss / Q000145:classification / Q000628:therapy; D010514:Periodontal Pocket / Q000145:classification / Q000628:therapy; D016966:Porphyromonas gingivalis / Q000302:isolation & purification; D011446:Prospective Studies; D016745:Root Planing / Q000379:methods; D016896:Treatment Outcome; D048373:Treponema denticola / Q000302:isolation & purification