title: Best practice in primary care pathology: review 14.
abstract: This 14th best practice review is the second of a pair that examines tumour marker requesting primary care situations. This review considers carbohydrate antigen 125, α-fetoprotein and human chorionic gonadotropin. It is presented in question-answer format, referenced for each question. The recommendations represent a précis of guidance found using a standardised literature search of national and international guidance notes, consensus statements, health policy documents and evidence-based medicine reviews, supplemented by MEDLINE EMBASE searches to identify relevant primary research documents. They will be updated periodically to take into account new information.
authors: Department of Clinical Biochemistry, Royal Berkshire and Battle NHS Trust, Reading, UK.
authors: J C
authors: JC
authors: Cabrera-Abreu
authors: W S A
authors: WS
authors: Smellie
authors: R
authors: R
authors: Bowley
authors: N
authors: N
authors: Shaw
mesh_terms: D014408:Biomarkers, Tumor / Q000032:analysis*; D018394:CA-125 Antigen / Q000032:analysis; D006063:Chorionic Gonadotropin / Q000032:analysis; D055088:Early Detection of Cancer / Q000379:methods*; D006801:Humans; D009369:Neoplasms / Q000175:diagnosis*; D011320:Primary Health Care; D011379:Prognosis; D012680:Sensitivity and Specificity; D000509:alpha-Fetoproteins / Q000032:analysis
chemical_list: C097353:AFP protein, human; D014408:Biomarkers, Tumor; D018394:CA-125 Antigen; D006063:Chorionic Gonadotropin; D000509:alpha-Fetoproteins