title: Will mineral trioxide aggregate replace calcium hydroxide in treating pulpal and periodontal healing complications subsequent to dental trauma? A review.
abstract: Mineral trioxide aggregate (MTA) has over the last two decades begun to take the place of calcium hydroxide (CH) in the treatment of a variety of pulpal and periodontal healing complications following dental trauma. These conditions include teeth with: (i) exposed pulps, (ii) immature roots and pulp necrosis, (iii) root fractures and pulp necrosis located in the coronal part of the pulps, and (iv) external infection-related (inflammatory) root resorption. The main reasons for replacing CH with MTA in these situations have generally been the delayed effect when using CH to induce hard tissues, the quality of such induced hard tissues, and finally the dentin weakening effect of CH, which in some instances lead to cervical root fractures in immature teeth. MTA appears, from a relatively few clinical studies, to overcome these shortcomings of CH. The lack of long-term clinical studies, however, may warrant a certain reservation in an unrestricted replacement of CH with MTA. A definite need for randomized clinical studies comparing CH and MTA in trauma healing situations is urgently needed.
authors: Department of Endodontics, School of Dentistry, Loma Linda University, Loma Linda, CA, USA.
authors: Leif K
authors: LK
authors: Bakland
authors: Jens O
authors: JO
authors: Andreasen
mesh_terms: D017607:Aluminum Compounds / Q000627:therapeutic use*; D056624:Apexification / Q000379:methods; D017610:Calcium Compounds / Q000627:therapeutic use*; D002126:Calcium Hydroxide / Q000627:therapeutic use*; D003788:Dental Pulp Diseases / Q000628:therapy*; D003809:Dentin, Secondary / Q000187:drug effects; D004338:Drug Combinations; D006801:Humans; D010087:Oxides / Q000627:therapeutic use*; D010510:Periodontal Diseases / Q000628:therapy*; D057872:Pulp Capping and Pulpectomy Agents / Q000627:therapeutic use; D012387:Root Canal Filling Materials / Q000627:therapeutic use*; D017640:Silicates / Q000627:therapeutic use*; D018677:Tooth Injuries / Q000150:complications*
chemical_list: D017607:Aluminum Compounds; D017610:Calcium Compounds; D004338:Drug Combinations; D010087:Oxides; D057872:Pulp Capping and Pulpectomy Agents; D012387:Root Canal Filling Materials; D017640:Silicates; C086631:mineral trioxide aggregate; D002126:Calcium Hydroxide