title: A facile and sensitive immunoassay for the detection of alpha-fetoprotein using gold-coated magnetic nanoparticle clusters and dynamic light scattering.
abstract: A facile and sensitive immunoassay protocol for the detection of alpha-fetoprotein (AFP) was developed using gold-coated iron oxide magnetic nanoclusters and dynamic light scattering (DLS) methods. The increase in the average particle size due to AFP-mediated aggregation was measured using DLS, and the detection limit was better than 0.01 ng mL(-1).
authors: Department of Chemical Engineering, Pohang University of Science and Technology (POSTECH), Pohang, Korea.
authors: Changho
authors: C
authors: Chun
authors: Jinmyoung
authors: J
authors: Joo
authors: Donghoon
authors: D
authors: Kwon
authors: Chang Sup
authors: CS
authors: Kim
authors: Hyung Joon
authors: HJ
authors: Cha
authors: Myung-Sub
authors: MS
authors: Chung
authors: Sangmin
authors: S
authors: Jeon
mesh_terms: D005290:Ferric Compounds / Q000737:chemistry*; D006046:Gold / Q000737:chemistry*; D007118:Immunoassay / Q000379:methods*; D008027:Light; D059346:Magnets / Q000737:chemistry; D053758:Nanoparticles / Q000737:chemistry*; D010316:Particle Size; D012542:Scattering, Radiation; D000509:alpha-Fetoproteins / Q000032:analysis*
chemical_list: D005290:Ferric Compounds; D000509:alpha-Fetoproteins; C000499:ferric oxide; D006046:Gold