title: A new twist on clock protein phosphorylation: a conformational change leads to protein degradation.
abstract: Progressive phosphorylation of circadian clock proteins is a hallmark of time-keeping. In this issue of Molecular Cell, Querfurth et al. (2011) demonstrate that phosphorylation of Neurospora FRQ induces a conformational change, which can account for its temporally gated degradation.
authors: Department of Biology, National Center for Behavioral Genomics, Brandeis University, 415 South Street, Waltham, MA 02454, USA.
authors: Jerome S
authors: JS
authors: Menet
authors: Michael
authors: M
authors: Rosbash