title: [Polymorphism of 17 short tandem repeat Loci of Tibetan minority ethnic group from Lhasa].
abstract: OBJECTIVE
  To investigate the polymorphism of 17 short tandem repeat (STR) loci of Tibetan minority ethnic group from Lhasa.
  
  
  METHODS
  Blood samples were obtained from 132 unrelated Tibetan individuals from Lhasa. DNA templates were screened by home-made AGCU17+1 kit and 3130XL genetic analyzer. Genotyping was performed using GeneMapper software (version 3.2).
  
  
  RESULTS
  The allele frequencies of 17 STR loci ranged 0.0038-0.5720, and the power of discrimination ranged 0.779-0.979, the power of exclusion ranged 0.327-0.737, the polymorphism information contents ranged 0.538-0.910, and the heterozygosity ranged 0.629-0.871. The cumulative coupling probability was 3.93 × 10(-20), and the cumulative power of exclusion was 0.9999995234. Of 17 STR loci, Penta E and D6S1043 had the highest polymorphism indicators, while TPOX had the lowest.
  
  
  CONCLUSIONS
  The 17 STR loci used in this study are highly polymorphism in Tibetan minority ethnic group from Lhasa and fit for the population genetic study and forensic cases.
authors: Detachment Criminal of Public Security Bureau of Changzhou, Changzhou, Jiangsu, China. liymajun@sina.com
authors: Jun
authors: J
authors: Ma
authors: Hua-jie
authors: HJ
authors: Ba
authors: Wen-jie
authors: WJ
authors: Zhang
authors: Kai
authors: K
authors: Li
mesh_terms: D044466:Asian People / Q000235:genetics; D005006:Ethnicity / Q000235:genetics; D005787:Gene Frequency; D005838:Genotype; D006801:Humans; D018895:Microsatellite Repeats / Q000235:genetics*; D008913:Minority Groups; D011110:Polymorphism, Genetic; D018609:Tibet