title: Large-scale functional brain networks in human non-rapid eye movement sleep: insights from combined electroencephalographic/functional magnetic resonance imaging studies.
abstract: This paper reviews the existing body of knowledge on the neural correlates of spontaneous oscillations, functional connectivity and brain plasticity in human non-rapid eye movement (NREM) sleep. The first section reviews the evidence that specific sleep events as slow waves and spindles are associated with transient increases in regional brain activity. The second section describes the changes in functional connectivity during NREM sleep, with a particular focus on changes within a low-frequency, large-scale functional brain network. The third section will discuss the possibility that spontaneous oscillations and differential functional connectivity are related to brain plasticity and systems consolidation, with a particular focus on motor skill acquisition. Implications for the mode of information processing per sleep stage and future experimental studies are discussed.
authors: RG Neuroimaging, Max Planck Institute of Psychiatry, Kraepelinstrasse 2-10, 80804 Munich, Germany. spoormaker@mpipsykl.mpg.de
authors: Victor I
authors: VI
authors: Spoormaker
authors: Michael
authors: M
authors: Czisch
authors: Pierre
authors: P
authors: Maquet
authors: Lutz
authors: L
authors: Jäncke
mesh_terms: D001921:Brain / Q000033:anatomy & histology / Q000502:physiology*; D004569:Electroencephalography / Q000379:methods*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D009415:Nerve Net / Q000033:anatomy & histology / Q000502:physiology*; D009473:Neuronal Plasticity; D012894:Sleep Stages / Q000502:physiology*