title: Extraskeletal osteosarcoma, telangiectatic variant arising from the small bowel mesentery.
abstract: Extraskeletal osteosarcoma (EOS) is a highly aggressive and rare malignant soft tissue tumor, characterized by the production of neoplastic osseous tissue without attachment to the bone or periosteum. It rarely involves the visceral organs. Only 3 cases of mesenteric EOS have been reported in English literature. Here, we describe a male patient of 40 years, who was diagnosed to have EOS arising from small bowel mesentery. This patient presented with lower gastrointestinal (GI) bleeding. Upper GI endoscopy and colonoscopy were normal. Computed tomography scan demonstrated a well defined multi-loculated mixed density mass lesion measuring about 13x7x7 cm in lower abdomen adjacent to small bowel loops with liver metastasis. Palliative en bloc resection of tumor with adjacent small bowel was performed. The histopathology revealed a telangiectatic type osteosarcoma of mesentery. Diagnosis of EOS, its management and the outcome in context of the current literature are discussed.
authors: Department of Surgery, King Saud University Unit, King Saud Medical City, Riyadh, Kingdom of Saudi Arabia. ibrarme@yahoo.com
authors: Muhammad I
authors: MI
authors: Hussain
authors: Mohammed H
authors: MH
authors: Al-Akeely
authors: Mohammed K
authors: MK
authors: Alam
authors: Nayel A
authors: NA
authors: Jasser
mesh_terms: D000328:Adult; D001859:Bone Neoplasms / Q000175:diagnosis / Q000473:pathology*; D016099:Endoscopy, Gastrointestinal; D006471:Gastrointestinal Hemorrhage / Q000209:etiology; D006801:Humans; D007421:Intestine, Small / Q000473:pathology; D008297:Male; D012516:Osteosarcoma / Q000175:diagnosis / Q000473:pathology*; D010534:Peritoneal Neoplasms / Q000175:diagnosis / Q000473:pathology*; D013684:Telangiectasis / Q000175:diagnosis / Q000473:pathology; D014057:Tomography, X-Ray Computed