title: [The concept of small volume resuscitation for preclinical trauma management. Experiences in the Air Rescue Service].
abstract: BACKGROUND
  Prompt hemorrhage control and adequate fluid resuscitation are the key components of early trauma care. However, the optimal resuscitation strategy remains controversial. In this context the small volume resuscitation (SVR) concept with hypertonic-hyperoncotic solutions is a new strategy.
  
  
  METHODS
  This was a retrospective study in the Helicopter Emergency Medical Service over a 5-year period. Included were all major trauma victims if they were candidates for SVR (initially 4 ml HyperHaes/kg body weight, followed by conventional fluid resuscitation with crystalloids and colloids). Demographic data, type and cause of injury and injury severity score (ISS) were recorded and the amount of fluid volume and the hemodynamic profile were analyzed. Negative side-effects as well as sodium chloride serum levels on hospital admission were recorded.
  
  
  RESULTS
  A total of 342 trauma victims (male 70.2%, mean age 39.0 ± 18.8 years, ISS 31.6 ± 16.9, ISS>16, 81.6%) underwent prehospital SVR. A blunt trauma mechanism was predominant (96.8%) and the leading cause of injury was motor vehicle accidents (61.5%) and motorcycle accidents (22.3%). Multiple trauma and polytrauma were noted in 87.4% of the cases. Predominant was traumatic brain injury (73.1%) as well as chest injury (73.1%) followed by limb injury (69.9%) and abdominal/pelvic trauma (45.0%). Within the whole study group in addition to 250 ml HyperHaes, mean volumes of 1214 ± 679 ml lactated Ringers and 1288 ± 954 ml hydroxethylstarch were infused during the prehospital treatment phase. There were no statistically significant differences in the amount of crystalloids and colloids infused regarding the subgroups multisystem trauma (ISS>16), severe traumatic brain injury (GCS<9) and entrapment trauma compared to the total study group. In patients with an initial systolic blood pressure (SBP) >80 mmHg significantly less colloids (1035 ± 659 ml vs. 1288 ± 954 ml, p<0.006) were infused, whereas in patients with an initial SBP ≤ 80 mmHg significantly more colloids were infused (1609 ± 1159 ml vs. 1288 ± 954 ml, p<0.002). There was a statistically significant increase in systolic as well as diastolic blood pressure at all times of blood pressure measurement during prehospital treatment after bolus infusion of HyperHaes within the whole study group. The same applies to the subgroups multisystem trauma, severe traumatic brain injury and entrapment trauma. Minor negative side-effects were observed in 4 cases (1.2%). The mean serum sodium chloride profile on hospital admission was 146.9 ± 5.0 mmol/l, the base excess (BE) was -5.7 ± 5.3 mmol/l) and the pH was 7.3 ± 0.1.
  
  
  CONCLUSIONS
  The concept of small volume resuscitation provides early and effective hemodynamic control. Clinical side-effects associated with bolus infusion of hypertonic-hyperoncotic solutions are rare.
authors: Sektion Notfallmedizin, Abteilung für Anästhesiologie & Intensivmedizin, Bundeswehrkrankenhaus Ulm, Oberer Eselsberg 40, 89070 Ulm. matthias.helm@extern.uni-ulm.de
authors: M
authors: M
authors: Helm
authors: J
authors: J
authors: Hauke
authors: J
authors: J
authors: Kohler
authors: L
authors: L
authors: Lampl
mesh_terms: D000328:Adult; D061906:Advanced Trauma Life Support Care / Q000706:statistics & numerical data*; D017732:Air Ambulances / Q000706:statistics & numerical data*; D015897:Comorbidity; D004632:Emergency Medical Services / Q000706:statistics & numerical data*; D005260:Female; D005440:Fluid Therapy / Q000379:methods / Q000706:statistics & numerical data*; D005858:Germany / Q000453:epidemiology; D006470:Hemorrhage / Q000453:epidemiology / Q000628:therapy*; D006801:Humans; D007552:Isotonic Solutions / Q000627:therapeutic use; D008297:Male; D015995:Prevalence; D012151:Resuscitation / Q000379:methods*; D018570:Risk Assessment; D016896:Treatment Outcome; D014947:Wounds and Injuries / Q000453:epidemiology / Q000628:therapy*
chemical_list: D007552:Isotonic Solutions