title: The role of the toxicologic pathologist in the biopharmaceutical industry.
abstract: Toxicologic pathologists contribute significantly to the development of new biopharmaceuticals, yet there is often a lack of awareness of this specialized role. As the members of multidisciplinary teams, toxicologic pathologists participate in all aspects of the drug development process. This review is part of an initiative by the Society of Toxicologic Pathology to educate scientists about toxicologic pathology and to attract junior scientists, veterinary students, and veterinarians into the field. We describe the role of toxicologic pathologists in identifying candidate agents, elucidating bioactive pathways, and evaluating efficacy and toxicity in preclinical animal models. Educational and specialized training requirements and the challenges of working in a global environment are discussed. The biopharmaceutical industry provides diverse, challenging, and rewarding career opportunities in toxicologic pathology. We hope that this review promotes understanding of the important role the toxicologic pathologist plays in drug development and encourages exploration of an important career option.
authors: Nonclinical Drug Safety US, Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, CT, USA.
authors: Susan
authors: S
authors: van Tongeren
authors: Jane A
authors: JA
authors: Fagerland
authors: Michael W
authors: MW
authors: Conner
authors: Kelly
authors: K
authors: Diegel
authors: Kevin
authors: K
authors: Donnelly
authors: Branka
authors: B
authors: Grubor
authors: Alric
authors: A
authors: Lopez-Martinez
authors: Anne Provencher
authors: AP
authors: Bolliger
authors: Alok
authors: A
authors: Sharma
authors: Sarah
authors: S
authors: Tannehill-Gregg
authors: Patricia V
authors: PV
authors: Turner
authors: Lyn M
authors: LM
authors: Wancket
mesh_terms: D000818:Animals; D001709:Biotechnology / Q000379:methods*; D055808:Drug Discovery; D004353:Drug Evaluation, Preclinical / Q000379:methods; D004345:Drug Industry / Q000193:education* / Q000639:trends; D006801:Humans; D010338:Pathology, Clinical / Q000193:education* / Q000639:trends; D018570:Risk Assessment; D013334:Students; D014116:Toxicology / Q000193:education* / Q000639:trends; D018634:Veterinarians