title: Simple and sensitive determination of low-molecular-mass aromatic aldehydes in swimming pool water by LC-diode array detector.
abstract: This work reports the development of a simple method for the quantitative determination of aromatic and aliphatic low-molecular-mass aldehydes (LMMAs) as disinfection by-products (DBPs) in indoor swimming pool waters after chlorination with a simplified SPE sample treatment. The method is based on the continuous in situ derivatization/preconcentration of the aldehydes with 2,4-dinitrophenylhydrazine (DNPH) on a Lichrolut EN column in the presence of β-CD. After elution, the 2,4-dinitrophenylhydrazine derivatives were separated on an RP-C(18) analytical column using gradient of ACN-water at 60-80%. The optimized sample treatment described here allowed the direct analysis of large volumes of water in order to improve the sensitivity of the method; LODs in the 60-120 ng/L range were achieved for aromatic LMMAs by using a volume of 50 mL of water, precision being 7.5% or better at a concentration level of 5 μg/L. These results indicate that the ensuing method is a useful choice for the determination of LMMAs in water samples that provides better results than reported LC alternatives in terms of the LOD (except for MS/MS detection), sample requirements for analysis and cost.
authors: Department of Analytical Chemistry, Marie-Curie Building (Annex), Rabanales Campus, University of Cordoba, Cordoba, Spain.
authors: José María
authors: JM
authors: Fernández-Molina
authors: Manuel
authors: M
authors: Silva
mesh_terms: D000447:Aldehydes / Q000737:chemistry*; D056148:Chromatography, Reverse-Phase / Q000379:methods*; D015394:Molecular Structure; D008970:Molecular Weight; D012680:Sensitivity and Specificity; D052616:Solid Phase Extraction / Q000379:methods*; D013551:Swimming Pools; D014874:Water Pollutants, Chemical / Q000737:chemistry*
chemical_list: D000447:Aldehydes; D014874:Water Pollutants, Chemical