title: Biomarker evaluation does not confirm efficacy of computer-tailored nutrition education.
abstract: OBJECTIVE
  To evaluate the efficacy of computer-tailored nutrition education with objective outcome measures.
  
  
  METHODS
  A 3-group randomized, controlled trial with posttests at 1 and 6 months post-intervention.
  
  
  METHODS
  Worksites and 2 neighborhoods in the urban area of Rotterdam.
  
  
  METHODS
  A convenience sample of healthy Dutch adults (n = 442).
  
  
  METHODS
  A computer-tailored intervention delivered on CD-ROM; a computer-tailored intervention delivered in print; and a generic information condition.
  
  
  METHODS
  Blood lipids (total, high-density lipoprotein, and low-density lipoprotein cholesterol, and triacylglycerol) were measured by analyzing venous blood samples.
  
  
  METHODS
  Linear mixed model procedure.
  
  
  RESULTS
  There were no significant differences among the 3 intervention groups in total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, and triacylglycerol.
  
  
  CONCLUSIONS
  Contrary to results based on self-report data, no effects of the computer-tailored interventions were found based on objective outcomes. This contradiction calls for a critical reflection on the use of computer-tailored nutrition education interventions and the need to improve those interventions. Furthermore, this study indicates that feasible methods are needed to objectively assess the impact of computer-tailored nutrition education interventions in free-living subjects.
authors: Department of Public Health, Erasmus University Medical Center, Rotterdam, The Netherlands. willemieke.kroeze@falw.vu.nl
authors: Willemieke
authors: W
authors: Kroeze
authors: Pieter C
authors: PC
authors: Dagnelie
authors: Martijn W
authors: MW
authors: Heymans
authors: Anke
authors: A
authors: Oenema
authors: Johannes
authors: J
authors: Brug
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D015415:Biomarkers / Q000097:blood; D003194:Computer-Assisted Instruction / Q000706:statistics & numerical data*; D005260:Female; D006266:Health Education / Q000379:methods* / Q000706:statistics & numerical data; D006801:Humans; D016014:Linear Models; D008075:Lipoproteins, HDL / Q000097:blood; D008077:Lipoproteins, LDL / Q000097:blood; D008297:Male; D008875:Middle Aged; D009426:Netherlands; D052756:Nutritional Sciences; D014280:Triglycerides / Q000097:blood
chemical_list: D015415:Biomarkers; D008075:Lipoproteins, HDL; D008077:Lipoproteins, LDL; D014280:Triglycerides