title: The histopathological feature of the nail isthmus in an ectopic nail.
abstract: The nail unit has a unique structure. It has been recently proposed that the nail isthmus as a transitional zone between the most distal part of the nail bed and the hyponychium. A 7-year-old Japanese boy presented with an ectopic nail, an additional and independent miniature nail on the digital pulp of the right fifth finger. We studied the expression of a series of keratin in longitudinal specimens and showed the histopathological manifestation in the nail isthmus. This region in the ectopic nail is subdivided into 2 parts: a proximal and narrow part anchored to the nail plate and a distal and wide part with a semihard keratinized structure.
authors: Department of Dermatology, Kinki University Faculty of Medicine, Osaka, Japan. naoiso@med.kindai.ac.jp
authors: Naoki
authors: N
authors: Oiso
authors: Ichiro
authors: I
authors: Kurokawa
authors: Daisuke
authors: D
authors: Tsuruta
authors: Tomohiko
authors: T
authors: Narita
authors: Takaaki
authors: T
authors: Chikugo
authors: Airo
authors: A
authors: Tsubura
authors: Masatomo
authors: M
authors: Kimura
authors: Robert
authors: R
authors: Baran
authors: Akira
authors: A
authors: Kawada
mesh_terms: D015415:Biomarkers / Q000032:analysis; D001706:Biopsy; D002648:Child; D002828:Choristoma; D005385:Fingers / Q000002:abnormalities* / Q000601:surgery; D006801:Humans; D007150:Immunohistochemistry; D007633:Keratins / Q000032:analysis; D008297:Male; D009262:Nails
chemical_list: D015415:Biomarkers; D007633:Keratins