title: [The levels of enzymes of blood neutrophilic leukocytes during the impact on the organism of vibration, vibration in aggregate with nickelous dust and nickel hydroaerosol].
abstract: The predominant impact of vibration and vibration in aggregate with nickelous dust and nickel hydroaerosol on the organism of workers administer significant influence on the levels of blood neutrophilic leukocytes and such neutrophil enzymes as acid and alkaline phosphatase and myeloperoxidase. In addition to that the activity of acid and alkaline phosphatases increases and the activity of myelopemroxidase reliably decreases. The intensive alteration of enzymes' activity develops already on the preclinical stage and even worsens in patients with vibratory disease. At the contact with the higher levels of nickel hydroaerosol the alteration of activity of these enzymes develops in early period at the experience less than 10 years.
authors: L I
authors: LI
authors: Antoshina
authors: N A
authors: NA
authors: Pavlovskaia
authors: I V
authors: IV
authors: Iatsyna
mesh_terms: D000135:Acid Phosphatase / Q000097:blood; D000469:Alkaline Phosphatase / Q000097:blood; D015415:Biomarkers / Q000097:blood*; D004391:Dust; D006801:Humans; D009504:Neutrophils / Q000201:enzymology*; D009532:Nickel / Q000009:adverse effects*; D009784:Occupational Diseases / Q000209:etiology*; D009195:Peroxidase / Q000097:blood; D013997:Time Factors; D014732:Vibration / Q000009:adverse effects*
chemical_list: D015415:Biomarkers; D004391:Dust; D009532:Nickel; D009195:Peroxidase; D000469:Alkaline Phosphatase; D000135:Acid Phosphatase