title: Research challenges and gaps in malaria knowledge in Papua New Guinea.
abstract: Taking into consideration the relative number of people living in Papua New Guinea the burden of malaria in this country is among the highest in Asia and the Pacific region. This article summarizes the research questions and challenges being undertaken by the Southwest Pacific International Center of Excellence for Malaria Research in the context of the epidemiology, transmission and pathogenesis of Plasmodium falciparum and P. vivax at the present time and the recent past. It is hoped that the research accomplished and local infrastructure strengthened by this effort will help inform regional and national policy with regard to the control and ultimately elimination of malaria in this region of the world.
authors: Center for Global Health & Diseases, Case Western Reserve University, School of Medicine, Cleveland, OH 44106-7286, USA. james.kazura@case.edu
authors: James W
authors: JW
authors: Kazura
authors: Peter M
authors: PM
authors: Siba
authors: Inoni
authors: I
authors: Betuela
authors: Ivo
authors: I
authors: Mueller
mesh_terms: D000818:Animals; D000852:Anopheles / Q000469:parasitology; D000962:Antimalarials / Q000494:pharmacology; D003695:Delivery of Health Care / Q000458:organization & administration; D018562:Disease Transmission, Infectious / Q000517:prevention & control*; D018432:Drug Resistance, Multiple; D015894:Genome, Human; D006291:Health Policy / Q000331:legislation & jurisprudence; D006302:Health Services Research / Q000379:methods / Q000458:organization & administration; D006801:Humans; D016778:Malaria, Falciparum / Q000188:drug therapy / Q000453:epidemiology* / Q000276:immunology / Q000469:parasitology; D016780:Malaria, Vivax / Q000188:drug therapy / Q000453:epidemiology* / Q000276:immunology / Q000469:parasitology; D009313:National Health Programs / Q000331:legislation & jurisprudence / Q000458:organization & administration*; D010219:Papua New Guinea / Q000453:epidemiology; D010963:Plasmodium falciparum / Q000276:immunology / Q000472:pathogenicity; D010966:Plasmodium vivax / Q000276:immunology / Q000472:pathogenicity; D011110:Polymorphism, Genetic; D015995:Prevalence; D012641:Selection, Genetic
chemical_list: D000962:Antimalarials