title: Inference for cumulative incidence quantiles via parametric and nonparametric approaches.
abstract: In survival analysis, a point estimate and confidence interval for median survival time have been frequently used to summarize the survival curve. However, such quantile analyses on competing risks data have not been widely investigated. In this paper, we propose parametric inferences for quantiles from the cumulative incidence function and develop parametric confidence intervals for quantiles. In addition, we study a simplified method of inference for the nonparametric approach. We compare the parametric and nonparametric inferences in empirical studies. Simulation studies show that the procedures perform well, with parametric analyses yielding smaller mean square error when the model is not too badly misspecified. We illustrate the methods with data from a breast cancer clinical trial.
authors: Department of Statistics, University of Wisconsin, Madison, WI 53706, USA. leem5@mail.nih.gov
authors: Minjung
authors: M
authors: Lee
authors: Jason P
authors: JP
authors: Fine
mesh_terms: D000368:Aged; D000972:Antineoplastic Agents, Phytogenic / Q000627:therapeutic use; D001943:Breast Neoplasms / Q000188:drug therapy; D003198:Computer Simulation; D016001:Confidence Intervals; D005260:Female; D006801:Humans; D015994:Incidence; D015233:Models, Statistical; D009364:Neoplasm Recurrence, Local; D016019:Survival Analysis; D013629:Tamoxifen / Q000627:therapeutic use
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D013629:Tamoxifen