title: Survival analysis of gastric cancer patients with tumor thrombus in the portal vein.
abstract: BACKGROUND
  A tumor thrombus in the portal vein originating from gastric cancer is a rare condition. Little is known about the development of portal vein tumor thrombus (PVTT) and its effect on the survival of gastric cancer patients.
  
  
  METHODS
  PVTT originating from gastric cancer was identified retrospectively with computed tomography in 51 patients, from January 2002 to June 2007. PVTT was classified by metastatic routes as follows: lymph node (LN), hepatic mass, and hematogenous type. The median survival from PVTT, and the factors affecting the survival of gastric cancer patients with PVTT were analyzed.
  
  
  RESULTS
  The median survival of gastric cancer patients with PVTT (N = 51) was 5.4 months. The median survival was compared according to clinical characteristics, and multivariate analysis proved that female and hepatic mass type were independent risk factors for poor prognosis. The characteristics of the hepatic mass type were old age, higher proportion of tumors located in the upper-third of the stomach, and liver metastasis, compared to the LN or the hematogeneous type.
  
  
  CONCLUSIONS
  PVTT originating from gastric cancer was a poor prognostic factor and the median survival from PVTT was different according to several clinical factors.
authors: Gastric Cancer Branch, Research Institute and Hospital, National Cancer Center, Gyeonggi-do, Korea.
authors: Bang Wool
authors: BW
authors: Eom
authors: Jun Ho
authors: JH
authors: Lee
authors: Jong Seok
authors: JS
authors: Lee
authors: Min Ju
authors: MJ
authors: Kim
authors: Keun Won
authors: KW
authors: Ryu
authors: Il Ju
authors: IJ
authors: Choi
authors: Soo-Jeong
authors: SJ
authors: Cho
authors: Jong Yeul
authors: JY
authors: Lee
authors: Jiyoung
authors: J
authors: Rhee
authors: Byung-Ho
authors: BH
authors: Nam
authors: Young-Woo
authors: YW
authors: Kim
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000401:mortality / Q000556:secondary; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D011169:Portal Vein / Q000000981:diagnostic imaging*; D011379:Prognosis; D012189:Retrospective Studies; D012737:Sex Factors; D013274:Stomach Neoplasms / Q000150:complications / Q000401:mortality*; D016019:Survival Analysis; D014057:Tomography, X-Ray Computed; D020246:Venous Thrombosis / Q000000981:diagnostic imaging / Q000209:etiology / Q000401:mortality*