title: Global aspects of drug development.
abstract: About nine million children die every year before they reach the age of 5 years, of conditions largely amendable with existing medicines. Lack of medicines is not the single most important health problem of children, but work to provide children with better access to appropriate medicines is essential for achievement of the child health goals set. Taking into consideration the global aspect in the development of paediatric medicines the benefits of the regional paediatric initiatives can be spread worldwide. This chapter provides insights in the challenges and opportunities of developing paediatric medicines for health needs of children in the developing world. The Essential Medicines List for children first made available in 2008 serves as an example of the many tools available from WHO to improve children's access to the medicines they need.
authors: Poison Information Centre, Helsinki University Central Hospital and Hospital for Children and Adolescents, Institute for Clinical Sciences, University of Helsinki, Helsinki, Finland. kalle.hoppu@hus.fi
authors: Kalle
authors: K
authors: Hoppu
authors: Hans V
authors: HV
authors: Hogerzeil
mesh_terms: D002626:Chemistry, Pharmaceutical; D002980:Climate; D002986:Clinical Trials as Topic / Q000941:ethics; D003469:Culture; D003906:Developing Countries; D004338:Drug Combinations; D018954:Drugs, Essential / Q000008:administration & dosage / Q000191:economics / Q000600:supply & distribution / Q000627:therapeutic use*; D006291:Health Policy; D006297:Health Services Accessibility; D006801:Humans; D038622:Internationality; D010372:Pediatrics; D011786:Quality Control; D014944:World Health Organization
chemical_list: D004338:Drug Combinations; D018954:Drugs, Essential