title: Previous conization on patient eligibility of sentinel lymph node detection for early invasive cervical cancer.
abstract: OBJECTIVE
  Sentinel lymph node (SLN) detection has been accepted as a common strategy to preserve the quality of life of the patients with gynecologic cancers. However, the feasibility of SLN detection after conization is not yet clarified. Accuracy of SLN after conization was evaluated.
  
  
  METHODS
  Eighteen cases with prior conization (cone group) and 32 cases without conization (noncone group), all of which belonged to IB1 except 1 case in IA stage, underwent SLN detection. Systemic pelvic and para-aortic lymphadenectomy was coincidently performed for the estimation of negative and positive predictive values.
  
  
  RESULTS
  Detection rate in which at least unilateral nodes were identified or bilaterally identified was 100% and 72.2% in the cone group, 90.6% and 71.9% in the noncone group, respectively. The average number of the detected SLN was 2.4 in the cone group and 2.1 in the noncone group. Negative and positive predictive value was 100% in both groups. On the distribution of sentinel node stations, most of the detected nodes were internal iliac and obturator node in both groups. Less frequent detection was observed in superficial common iliac node (5.4% in the cone group, 3.1% in the noncone group), external iliac node (2.7% and 9.5%), and parauterine artery node (5.4% and 1.6%).In both groups, no other lymph nodes were identified as SLN except 1 case in the cone group with the node in cardinal ligament.
  
  
  CONCLUSIONS
  No significant difference was observed on detection rate, predictive value, and the distribution of sentinel node between the cone and noncone groups. Sentinel lymph node detection after conization can be performed with a certain reliability.
authors: Division of Gynecologic Oncology, National Hospital Organization, Hokkaido Cancer Center, Sapporo, Japan. hidekato@sap-cc.go.jp
authors: Hidenori
authors: H
authors: Kato
authors: Yukiharu
authors: Y
authors: Todo
authors: Shin-Ichiro
authors: S
authors: Minobe
authors: Yoshihiro
authors: Y
authors: Suzuki
authors: Makiko
authors: M
authors: Nakatani
authors: Yoko
authors: Y
authors: Ohba
authors: Katsusige
authors: K
authors: Yamashiro
authors: Kazuhira
authors: K
authors: Okamoto
mesh_terms: D019092:Conization; D005260:Female; D006801:Humans; D011237:Predictive Value of Tests; D021701:Sentinel Lymph Node Biopsy; D002583:Uterine Cervical Neoplasms / Q000473:pathology* / Q000601:surgery