title: [Prognostic factors for gastric cancer without lymph node involvement].
abstract: BACKGROUND
  The absence of lymph node involvement (N0) in gastric cancer is associated with a better survival. However some N0 gastric tumors still have a bad prognosis.
  
  
  OBJECTIVE
  To study demographic and morphological variables associated with prognosis in N0 gastric carcinoma.
  
  
  METHODS
  Review of pathological records of a regional general hospital, identifying patients with a N0 gastric cancer surgically excised between 1986 and 2003.
  
  
  RESULTS
  In the study period, 459 gastrectomies were performed for gastric cancer and in 32%, the tumor was devoid of lymph node involvement. These later patients were followed for a median of 64 months with a 71% five years actuarial survival. Bivariate analysis identified age, tumor size, gastric wall infiltration, pathological type according to Lauren and Ming, lymphovascular involvement, number of lymph nodes excised and TNM stage as prognostic values Multivariate analysis disclosed the level of gastric wall infiltration, the presence of a poorly differentiated tumor, lymphatic vascular involvement, number of excise lymph nodes and tumor size as independent prognostic factors.
  
  
  CONCLUSIONS
  N0 gastric tumors are found in 32% of gastrectomies for gastric cancer and have a 71% five years actuarial survival. Gastric wall infiltration, pathological degree of differentiation tumor size and lymphovascular involvement are independent prognostic factors.
authors: Departamento de Anatomía Patológica, Facultad de Medicina, Universidad de La Frontera, Temuco, Chile. otescalona@gmail.com
authors: Oscar
authors: O
authors: Tapia
authors: Miguel
authors: M
authors: Villaseca
authors: Enrique
authors: E
authors: Bellolio
authors: Juan Carlos
authors: JC
authors: Araya
authors: Juan Carlos
authors: JC
authors: Roa
mesh_terms: D015331:Cohort Studies; D005260:Female; D005743:Gastrectomy; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness / Q000473:pathology; D009367:Neoplasm Staging; D011379:Prognosis; D012189:Retrospective Studies; D013274:Stomach Neoplasms / Q000401:mortality / Q000473:pathology* / Q000556:secondary / Q000601:surgery; D016019:Survival Analysis