title: Surgery for tardive dyskinesia.
abstract: Tardive dyskinesia (TD) is an often bothersome side effect of antipsychotic treatment. Medical treatment options are usually disappointing. A few single case reports have suggested some efficacy of lesionning surgery (i.e. pallidotomy or thalamotomy). A much greater number of series (including one controlled-study) have assessed the effects of deep brain stimulation applied to the internal globus pallidus. All of them have shown a marked improvement of motor symptoms without any major psychiatric side effects.
authors: Université Lyon I; Hospices Civils de Lyon, Hôpital Neurologique Pierre Wertheimer, service de Neurologie C, Lyon, France.
authors: Stéphane
authors: S
authors: Thobois
authors: Alice
authors: A
authors: Poisson
authors: Philippe
authors: P
authors: Damier
mesh_terms: D014150:Antipsychotic Agents / Q000009:adverse effects; D046690:Deep Brain Stimulation / Q000379:methods; D005917:Globus Pallidus / Q000502:physiology; D006801:Humans; D009069:Movement Disorders / Q000209:etiology / Q000628:therapy*; D053860:Pallidotomy / Q000379:methods; D013788:Thalamus / Q000502:physiology / Q000601:surgery
chemical_list: D014150:Antipsychotic Agents