title: The in vivo anti-plasmodial activity of haliclonacyclamine A, an alkaloid from the marine sponge, Haliclona sp.
abstract: The compound haliclonacyclamine A was isolated from the Haliclona sponge at Solomon Islands. It acts as a powerful in vitro and in vivo anti-plasmodial agent against the chloroquine-resistant Plasmodium falciparum strain FCB1and Plasmodium vinckei petteri-infected mice, respectively.
authors: Faculté des Sciences Pharmaceutiques, UMR152, IRD-Université Paul Sabatier, Toulouse III, 31062 Toulouse Cedex 9, France.
authors: L
authors: L
authors: Mani
authors: S
authors: S
authors: Petek
authors: A
authors: A
authors: Valentin
authors: S
authors: S
authors: Chevalley
authors: E
authors: E
authors: Folcher
authors: W
authors: W
authors: Aalbersberg
authors: C
authors: C
authors: Debitus
mesh_terms: D000818:Animals; D045744:Cell Line, Tumor; D005260:Female; D047129:Haliclona / Q000737:chemistry*; D006801:Humans; D047028:Macrocyclic Compounds / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology* / Q000627:therapeutic use; D009682:Magnetic Resonance Spectroscopy; D008288:Malaria / Q000188:drug therapy*; D008542:Melanesia; D051379:Mice; D015394:Molecular Structure; D010880:Piperidines / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology* / Q000627:therapeutic use; D010961:Plasmodium / Q000187:drug effects*; D016019:Survival Analysis
chemical_list: D047028:Macrocyclic Compounds; D010880:Piperidines; C114409:haliclonacyclamine A