title: Effect of four different vegetable oils (red palm olein, palm olein, corn oil, coconut oil) on antioxidant enzymes activity of rat liver.
abstract: The objective of the study was to evaluate the effect of four different vegetable oils [red palm olein (RPO), palm olein (PO), corn oil (CO), coconut oil (COC)] on antioxidant enzymes activity of rat liver. Sixty six Sprague Dawley male rats which were randomly divided into eleven groups of 6 rats per group and were treated with 15% of RPO, PO, CO and COC for 4 and 8 weeks. Rats in the control group were given normal rat pellet only while in treated groups, 15% of additional different vegetable oils were given. After 4 weeks of treatment the catalase (CAT) activity results showed that there was no significance difference (p > or = 0.05) between the control group and treated groups while after 8 weeks of treatment showed that there was no significant different (p > or = 0.05) between control group and RPO group but the treated rat liver with PO, CO and COC groups were the lowest and it were significantly lower (> or = 0.05) than control group. For superoxide dismutase (SOD) there was no significance difference (p > or = 0.05) between the control group and treated groups of vegetable oils after 4 and 8 weeks of treatment. Thus the study indicated that there was no significant (p > or = 0.05) effect on antioxidant enzyme (superoxide dismutase) but there was significant effect (p > or = 0.05) on catalase in rat liver.
authors: School of Biosciences and Biotechnology, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, 43600 Bangi Selangor, Malaysia.
authors: Eqbal
authors: E
authors: Dauqan
authors: Halimah Abdullah
authors: HA
authors: Sani
authors: Aminah
authors: A
authors: Abdullah
authors: Zalifah Mohd
authors: ZM
authors: Kasim
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000378:metabolism / Q000494:pharmacology; D002338:Carotenoids / Q000494:pharmacology; D002374:Catalase / Q000378:metabolism; D000074263:Coconut Oil; D003314:Corn Oil / Q000494:pharmacology; D008099:Liver / Q000187:drug effects* / Q000201:enzymology*; D008297:Male; D018384:Oxidative Stress / Q000187:drug effects; D000073878:Palm Oil; D010938:Plant Oils / Q000494:pharmacology*; D051381:Rats; D017207:Rats, Sprague-Dawley; D013482:Superoxide Dismutase / Q000378:metabolism; D014810:Vitamin E / Q000494:pharmacology
chemical_list: D000975:Antioxidants; D010938:Plant Oils; D014810:Vitamin E; D002338:Carotenoids; D000073878:Palm Oil; D003314:Corn Oil; D002374:Catalase; D013482:Superoxide Dismutase; D000074263:Coconut Oil