title: Two antifungal active triterpenoid saponins from the seeds of Lathyrus plants.
abstract: Two novel triterpenoid glycosides have been isolated from butanolic seeds extract of two varieties of Lathyrus plants, i.e. Lathyrus ratan and Lathyrus aphaca. Their structures were elucidated as 3-O-[β-D-glucuronopyranosyl-(1 → 4)-α-L-arabinopyranosyl-(1 → 2)-α-L-arabinopyranosyl]-olean-11,13(18)-dien-28-oic acid (1) and 3-O-{β-D-xylopyranosyl-(1  →  2)-β-D-glcopyranosyl-(1 → 4)-[β-D-glucopyranosyl-(1 → 2)]-β-D-xylopyranosyl}-2,16α-dihydroxy-4-hydroxymethyl urs-12-en-28-oic acid (2) on the basis of spectral evidences, i.e. FTIR, (1)H-NMR, (13)C-NMR, ESI-MS and FAB-MS data. The isolated saponins were tested for their antifungal activity. Compound 1 showed maximum inhibition against Colletotrichum dematium (77.8%), whereas compound 2 showed maximum inhibition against Alternaria alternata (53.9%).
authors: Department of Postgraduate and Research in Chemistry, R. D. University of Jabalpur, Jabalpur - 482001, M.P., India. noor_afshan25@yahoo.com
authors: Noor Afshan
authors: NA
authors: Khan
mesh_terms: D000528:Alternaria / Q000187:drug effects; D000935:Antifungal Agents / Q000032:analysis / Q000302:isolation & purification* / Q000494:pharmacology; D000440:Butanols; D020231:Colletotrichum / Q000187:drug effects; D027807:Lathyrus / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D012503:Saponins / Q000032:analysis / Q000302:isolation & purification* / Q000494:pharmacology; D012639:Seeds / Q000737:chemistry*; D013045:Species Specificity; D021241:Spectrometry, Mass, Electrospray Ionization; D017550:Spectroscopy, Fourier Transform Infrared; D014315:Triterpenes / Q000032:analysis / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: D000935:Antifungal Agents; D000440:Butanols; D012503:Saponins; D014315:Triterpenes