title: Alkaloids from Hippeastrum morelianum Lem. (Amaryllidaceae).
abstract: The Amaryllidaceae family has proven to be a rich source of active molecules. As part of an ongoing project, we report a phytochemical study of Hippeastrum morelianum (Amaryllidaceae), from which we have isolated two homolycorine-type alkaloids, the new 2α,7-dimethoxyhomolycorine (1) and the poorly described candimine (2), as well as six known alkaloids: tazettine, pretazettine, 3-epimacronine, haemanthamine, hamayne and trisphaeridine. For reference purposes, the NMR of the isolated compounds was unequivocally described, based on 2D NMR measurements including (1)H-(1)H COSY, (1)H-(1)H NOESY, HSQC and HMBC.
authors: Raquel B
authors: RB
authors: Giordani
authors: Jean P
authors: JP
authors: de Andrade
authors: Hugo
authors: H
authors: Verli
authors: Julie H
authors: JH
authors: Dutilh
authors: Amélia T
authors: AT
authors: Henriques
authors: Strahil
authors: S
authors: Berkov
authors: Jaume
authors: J
authors: Bastida
authors: José Angelo S
authors: JA
authors: Zuanazzi
mesh_terms: D000470:Alkaloids / Q000737:chemistry* / Q000302:isolation & purification; D003198:Computer Simulation; D018360:Crystallography, X-Ray; D019668:Liliaceae / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy / Q000592:standards; D008958:Models, Molecular; D015394:Molecular Structure; D010936:Plant Extracts / Q000737:chemistry* / Q000302:isolation & purification; D012015:Reference Standards; D013237:Stereoisomerism
chemical_list: D000470:Alkaloids; D010936:Plant Extracts