title: Thrombocytopenia in cardiac surgery: diagnostic and prognostic importance.
abstract: OBJECTIVE
  Patients undergo to cardiac surgery have more probability to develop thrombocytopenia. The heparin induced thrombocytopenia happens in 5% of the patients. The aim from this study was to evaluate the clinical importance from the severe thrombocytopenia in postoperative cardiac surgical patients.
  
  
  METHODS
  It was included cardiac surgical patients with platelets < 150000 cel/mm³ during firsts 24 h from postoperative. All patients underwent evaluation for four Ts score (thrombocytopenia, use preview of heparin, thrombosis and platelets decreased not related to heparin). In order to a four Ts score e" 6 was considered as suggestive of heparin induced thrombocytopenia type II. The mortality rate in intensive care (ICU) and hospital, length of stay, healthy state and incidence from thrombosis were compared in patients with score > 6 (group 1) and < 6 (group 2).
  
  
  RESULTS
  It was include 120 patients who met the inclusions criterions. There was no difference between the groups in related to age, gender, time of cardiopulmonary bypass and surgery. However, the incidence of thrombosis was higher in group 1 (23% vs. 0%, P<0.0001), as well as the greater score is related to higher hospital mortality rate.
  
  
  CONCLUSIONS
  The score > 6, in postoperative cardiac surgical patients, it is associated to higher incidence of thrombosis as well as the greater score is related to higher hospital mortality rate.
authors: Intensive Care Service, State Civil Servant Hospital.
authors: Ederlon
authors: E
authors: Rezende
authors: Gustavo
authors: G
authors: Morais
authors: João Manoel
authors: JM
authors: Silva Junior
authors: Amanda Maria Ribas Rosa de
authors: AM
authors: Oliveira
authors: Jose Marconi Almeida
authors: JM
authors: Souza
authors: Diogo Oliveira
authors: DO
authors: Toledo
authors: Ivo
authors: I
authors: Richter
authors: Enock Meira
authors: EM
authors: Brandão
mesh_terms: D000925:Anticoagulants / Q000009:adverse effects; D006348:Cardiac Surgical Procedures / Q000009:adverse effects*; D005260:Female; D006493:Heparin / Q000009:adverse effects; D017052:Hospital Mortality; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D011446:Prospective Studies; D018570:Risk Assessment / Q000379:methods; D013921:Thrombocytopenia / Q000175:diagnosis* / Q000209:etiology / Q000401:mortality
chemical_list: D000925:Anticoagulants; D006493:Heparin