title: Synthesis of the 6-O-methyl-D-glycero-α-L-gluco-heptopyranose moiety present in the capsular polysaccharide from Campylobacter jejuni NCTC 11168.
abstract: The first synthesis of the 6-O-methyl-D-glycero-α-L-gluco-heptopyranose moiety present in the capsular polysaccharide from Campylobacter jejuni NCTC 11168 is reported. The target (1) was synthesized as the 8-aminooctyl glycoside and then conjugated to bovine serum albumin (BSA) for the generation of antibodies recognizing this motif. Heptose 1 was obtained from D-galactose via a series of galactofuranose derivatives.
authors: Alberta Innovates Centre for Carbohydrate Science and Department of Chemistry, The University of Alberta, Gunning-Lemieux Chemistry Centre, Edmonton, AB T6G 2G2 Canada.
authors: Wenjie
authors: W
authors: Peng
authors: Anushka B
authors: AB
authors: Jayasuriya
authors: Akihiro
authors: A
authors: Imamura
authors: Todd L
authors: TL
authors: Lowary
mesh_terms: D000818:Animals; D016123:Campylobacter jejuni / Q000737:chemistry*; D002417:Cattle; D005990:Glycerol / Q000031:analogs & derivatives* / Q000138:chemical synthesis; D015394:Molecular Structure; D009005:Monosaccharides / Q000138:chemical synthesis*; D011134:Polysaccharides / Q000737:chemistry*; D012710:Serum Albumin, Bovine / Q000737:chemistry
chemical_list: C569216:6-O-methyl-D-glycero-alpha-L-gluco-heptopyranose; D009005:Monosaccharides; D011134:Polysaccharides; D012710:Serum Albumin, Bovine; D005990:Glycerol