title: [The characteristics of iron metabolism under iron-deficiency anemia and chronic disorders anemia].
abstract: The study investigated the issues of iron metabolism under iron-deficiency anemia and chronic disorders anemia and dependencies of production of IL-1? and sICAM-1 immunoinflammatory markers from degree of severity and duration of anemia. The study data indicates that under iron-deficiency anemia lactoferrin and sICAM-1 are the negative regulators of hemopoiesis. The inhibition of transferrin expression by the proinflammatory cytokines is one of the causes of inefficient hemopoiesis under chronic disorders anemia.
authors: E V
authors: EV
authors: Smorkalova
authors: L F
authors: LF
authors: Aznabaeva
authors: V I
authors: VI
authors: Nikulicheva
authors: G Sh
authors: GSh
authors: Safuanova
authors: A N
authors: AN
authors: Chepurnaia
mesh_terms: D000328:Adult; D018798:Anemia, Iron-Deficiency / Q000503:physiopathology*; D015415:Biomarkers / Q000097:blood; D002908:Chronic Disease; D004920:Erythropoiesis / Q000502:physiology; D004921:Erythropoietin / Q000097:blood; D005260:Female; D006801:Humans; D018799:Intercellular Adhesion Molecule-1 / Q000097:blood; D053583:Interleukin-1beta / Q000097:blood; D007501:Iron / Q000378:metabolism*; D033862:Iron-Binding Proteins / Q000097:blood* / Q000378:metabolism; D008297:Male; D008875:Middle Aged
chemical_list: D015415:Biomarkers; D053583:Interleukin-1beta; D033862:Iron-Binding Proteins; D004921:Erythropoietin; D018799:Intercellular Adhesion Molecule-1; D007501:Iron