title: Simultaneous determination of ten ginsenosides in panacis quinquefolii radix by ultra performance liquid chromatography and quality evaluation based on chemometric methods.
abstract: A rapid, sensitive and reliable method based on ultra performance liquid chromatography coupled with a photodiode array detector (UPLC-PAD) was developed for both the quantitative analysis of ten bioactive ginsenosides and a chemical-fingerprint analysis. The chromatography was performed on an ACQUITY UPLC BEH C18 column using a gradient elution with acetonitrile/water as the mobile phase. To compare the UPLC fingerprints and to evaluate their quality, chemometric methods including similarity analysis (SA) and hierarchical-clustering analysis (HCA) were implemented when classifying the Panacis Quinquefolii Radix samples. The Panacis Quinquefolii Radix samples were successfully grouped in accordance with their geographic origins.
authors: Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
authors: C Y
authors: CY
authors: Zhang
authors: L
authors: L
authors: Dong
authors: J
authors: J
authors: Wang
authors: S L
authors: SL
authors: Chen
mesh_terms: D002138:Calibration; D002851:Chromatography, High Pressure Liquid; D016000:Cluster Analysis; D003627:Data Interpretation, Statistical; D036145:Ginsenosides / Q000032:analysis*; D007202:Indicators and Reagents; D005894:Panax / Q000737:chemistry*; D018517:Plant Roots / Q000737:chemistry; D011786:Quality Control; D012015:Reference Standards; D015203:Reproducibility of Results
chemical_list: D036145:Ginsenosides; D007202:Indicators and Reagents