title: Invasive group B streptococcal infections in adults, France (2007-2010).
abstract: Group B streptococcus (GBS) has emerged as an important cause of invasive infection in adults. Here, we report the clinical and microbiological characteristics of 401 non-redundant GBS strains causing adult invasive infections collected during a 4-year period (2007-2010). Bacteraemia without focus (43.4%) and bone and joint infections (18.7%) were the main clinical manifestations. The distribution of capsular polysaccharide (CPS) type showed that types Ia, III, and V accounted for 71.8% of all strains. Resistance to erythromycin increased from 20.2% in 2007 to 35.3% in 2010, and was mainly associated with CPS type V harbouring the erm(B) resistant determinant.
authors: Centre National de Référence des Streptocoques (CNR-Strep), Groupe Hospitalier Cochin-Hôtel Dieu-Broca Assistance Publique Hôpitaux de Paris, Paris, France.
authors: A
authors: A
authors: Tazi
authors: P C
authors: PC
authors: Morand
authors: H
authors: H
authors: Réglier-Poupet
authors: N
authors: N
authors: Dmytruk
authors: A
authors: A
authors: Billoët
authors: D
authors: D
authors: Antona
authors: P
authors: P
authors: Trieu-Cuot
authors: C
authors: C
authors: Poyart
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016470:Bacteremia / Q000453:epidemiology / Q000382:microbiology; D016667:Bacterial Capsules / Q000032:analysis; D001842:Bone and Bones / Q000382:microbiology; D024881:Drug Resistance, Bacterial; D004917:Erythromycin / Q000494:pharmacology; D005260:Female; D005602:France / Q000453:epidemiology; D005798:Genes, Bacterial; D006801:Humans; D007596:Joints / Q000382:microbiology; D008297:Male; D008875:Middle Aged; D010641:Phenotype; D013290:Streptococcal Infections / Q000453:epidemiology / Q000382:microbiology*; D013292:Streptococcus agalactiae / Q000187:drug effects / Q000235:genetics / Q000472:pathogenicity*; D055815:Young Adult
chemical_list: C068312:capsular polysaccharide, streptoccal group B type V; D004917:Erythromycin