title: Acute mixed cellular and humoral rejection of renal allograft with leucopenia.
abstract: Diagnosis and management of acute renal allograft dysfunction often pose challenge to nephrologists during practice. Acute rejection is a major cause of acute graft dysfunction but is rare in patients with leucopenia. Acute rejection can have either humoral or cellular components or sometimes mixed components. Mixed acute cellular and humoral rejection often present as steroid resistant rejection. Here we report a patient with live related renal transplant recipient with acute graft dysfunction with leucopenia who was found to have mixed acute cellular and humoral rejection.
authors: Dept. of Nephrology, Indraprastha Apollo Hospitals, New Delhi.
authors: D K
authors: DK
authors: Agarwal
authors: J K
authors: JK
authors: Hota
authors: V
authors: V
authors: Malhotra
mesh_terms: D000328:Adult; D000961:Antilymphocyte Serum / Q000627:therapeutic use; D001706:Biopsy; D006084:Graft Rejection / Q000175:diagnosis / Q000188:drug therapy*; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D016030:Kidney Transplantation / Q000009:adverse effects*; D007970:Leukopenia / Q000139:chemically induced*; D008297:Male; D009173:Mycophenolic Acid / Q000009:adverse effects / Q000031:analogs & derivatives*; D010951:Plasma Exchange; D011239:Prednisolone / Q000627:therapeutic use; D016559:Tacrolimus / Q000627:therapeutic use; D014184:Transplantation, Homologous; D016896:Treatment Outcome; D018608:Ultrasonography, Doppler
chemical_list: D000961:Antilymphocyte Serum; D007166:Immunosuppressive Agents; D011239:Prednisolone; D009173:Mycophenolic Acid; D016559:Tacrolimus