title: [The new approach in diagnostics of systemic lupus erythematosus: the immunoagglutination of collaurin].
abstract: The data is presented concerning the implementation of nano-particles of aurum in the diagnostics of systemic lupus erythematosus. It is demonstrated that nano-particles sensibilized by deoxyribonucleoprotein are able to detect the specific antibodies--the known markers of systemic lupus erythematosus. To optimize the reaction various approaches were applied. The comparative analysis was made including latex-agglutination technique, immune-enzyme analysis and fluorescence immunoassay. It is demonstrated that the given system is characterized by very high sensibility to determine the specific antibodies and hence can be effectively applied in diagnostics process.
authors: É É
authors: ÉÉ
authors: Eritsian
mesh_terms: D000372:Agglutination Tests / Q000379:methods*; D000818:Animals; D000974:Antibodies, Antinuclear / Q000276:immunology*; D004247:DNA / Q000276:immunology; D006046:Gold / Q000737:chemistry*; D006657:Histones / Q000276:immunology; D006801:Humans; D007118:Immunoassay; D008180:Lupus Erythematosus, Systemic / Q000175:diagnosis* / Q000276:immunology; D053768:Metal Nanoparticles / Q000737:chemistry*; D012313:RNA / Q000276:immunology; D051381:Rats; D020349:Surface Plasmon Resonance
chemical_list: D000974:Antibodies, Antinuclear; D006657:Histones; D012313:RNA; D006046:Gold; D004247:DNA