title: Novel hybrid vesicles co-assembled from a cationic lipid and PAAc-g-mPEG with pH-triggered transmembrane channels for controlled drug release.
abstract: This work presents an important example of novel hybrid vesicles with pH-triggered transmembrane channels prepared by co-assembly of poly(acrylic acid)-g-poly(monomethoxy ethylene glycol) (PAAc-g-mPEG) with a cationic lipid, didodecyldimethylammonium bromide (DDAB), via electrostatic interaction for effective doxorubicin (DOX) release.
authors: Department of Chemical Engineering, National Chung Hsing University, Taichung 402, Taiwan.
authors: Yi-Fong
authors: YF
authors: Huang
authors: Wen-Hsuan
authors: WH
authors: Chiang
authors: Pei-Ling
authors: PL
authors: Tsai
authors: Chorng-Shyan
authors: CS
authors: Chern
authors: Hsin-Cheng
authors: HC
authors: Chiu
mesh_terms: D000180:Acrylic Resins / Q000737:chemistry*; D002462:Cell Membrane / Q000378:metabolism*; D003692:Delayed-Action Preparations; D004317:Doxorubicin / Q000737:chemistry / Q000378:metabolism; D004337:Drug Carriers / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D008958:Models, Molecular; D008968:Molecular Conformation; D010316:Particle Size; D011092:Polyethylene Glycols / Q000737:chemistry*; D000644:Quaternary Ammonium Compounds / Q000737:chemistry*
chemical_list: D000180:Acrylic Resins; D003692:Delayed-Action Preparations; D004337:Drug Carriers; D000644:Quaternary Ammonium Compounds; C046112:didodecyldimethylammonium; D011092:Polyethylene Glycols; C006903:carbopol 940; D004317:Doxorubicin; C028210:monomethoxypolyethylene glycol