title: The Ax21 protein is a cell-cell signal that regulates virulence in the nosocomial pathogen Stenotrophomonas maltophilia.
abstract: Stenotrophomonas maltophilia encodes proteins related to the Rax proteins of Xanthomonas oryzae, which are required for the synthesis and secretion of the Ax21 protein. Here we show that Ax21 acts as a cell-cell signal to regulate a diverse range of functions, including virulence, in this nosocomial pathogen.
authors: BIOMERIT Research Centre, Department of Microbiology, Biosciences Institute, University College Cork, Cork, Ireland.
authors: Yvonne
authors: Y
authors: McCarthy
authors: J Maxwell
authors: JM
authors: Dow
authors: Robert P
authors: RP
authors: Ryan
mesh_terms: D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism*; D003428:Cross Infection / Q000382:microbiology*; D015964:Gene Expression Regulation, Bacterial; D006801:Humans; D015398:Signal Transduction; D020615:Stenotrophomonas maltophilia / Q000235:genetics / Q000378:metabolism* / Q000472:pathogenicity*; D014774:Virulence; D014974:Xanthomonas / Q000235:genetics / Q000378:metabolism / Q000472:pathogenicity
chemical_list: D001426:Bacterial Proteins