title: Synthesis of oligoribonucleotides containing 2'-O-methoxymethyl group by the phosphotriester method.
abstract: An effective procedure for the synthesis of ribonucleotide monomers containing a 2 '-О-methoxymethyl-modifying group was developed. These monomers were used for the synthesis of RNA fragments by the solid-phase phosphotriester method under O-nucleophilic intramolecular catalysis. The properties of 2 '-О-methoxymethyl-containing oligoribonucleotides were examined.
authors: Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.
authors: Vladimir A
authors: VA
authors: Efimov
authors: Andrey V
authors: AV
authors: Aralov
authors: Oksana G
authors: OG
authors: Chakhmakhcheva
mesh_terms: D002384:Catalysis; D009843:Oligoribonucleotides / Q000138:chemical synthesis* / Q000737:chemistry; D010756:Phosphoric Acids / Q000737:chemistry; D012313:RNA / Q000138:chemical synthesis* / Q000737:chemistry; D060327:Solid-Phase Synthesis Techniques / Q000191:economics / Q000379:methods*
chemical_list: D009843:Oligoribonucleotides; D010756:Phosphoric Acids; D012313:RNA