title: Metastatic choroidal paraganglioma.
abstract: OBJECTIVE
  To describe a patient with metastatic choroidal paraganglioma that was locally controlled with radiotherapy.
  
  
  METHODS
  Interventional clinicopathologic case report.
  
  
  METHODS
  One patient with metastatic choroidal paraganglioma.
  
  
  METHODS
  Interventional clinicopathologic case report and systematic search of the literature.
  
  
  METHODS
  Description of clinicopathologic features, treatment methods, and outcome.
  
  
  RESULTS
  A 50-year-old man had a nonpigmented atypical choroidal mass with secondary retinal detachment in the left eye. After incisional biopsy, the diagnosis of paraganglioma was established. Metastatic work-up revealed vertebral, mediastinal, and pulmonary metastases of a nonsecretory, malignant paraganglioma without tracer uptake. The primary tumor was not identified. The ocular tumor regressed after stereotaxic radiotherapy. Two years later, recurrent lesions developed in the contralateral eye, which also was irradiated.
  
  
  CONCLUSIONS
  Malignant paraganglioma can metastasize in the choroid and should be included in the differential diagnosis of a nonpigmented choroidal mass. Stereotaxic radiation therapy is an effective treatment method. To the authors' knowledge, this is the first report of a patient with choroidal paraganglioma.
  
  
  BACKGROUND
  The author(s) have no proprietary or commercial interest in any materials discussed in this article.
authors: Jules-Gonin Eye Hospital, University of Lausanne, Lausanne, Switzerland. ann.schalenbourg@fa2.ch
authors: Ann
authors: A
authors: Schalenbourg
authors: Alexandre
authors: A
authors: Moulin
authors: Louis
authors: L
authors: Guillou
authors: Leonidas
authors: L
authors: Zografos
mesh_terms: D002830:Choroid Neoplasms / Q000000981:diagnostic imaging / Q000532:radiotherapy / Q000556:secondary*; D006801:Humans; D008175:Lung Neoplasms / Q000556:secondary*; D008297:Male; D008479:Mediastinal Neoplasms / Q000556:secondary*; D008875:Middle Aged; D010235:Paraganglioma / Q000000981:diagnostic imaging / Q000532:radiotherapy / Q000556:secondary*; D013125:Spinal Neoplasms / Q000556:secondary*; D014463:Ultrasonography; D014792:Visual Acuity / Q000502:physiology