title: Evaluation of a single-channel portable monitor for the diagnosis of obstructive sleep apnea.
abstract: OBJECTIVE
  To validate the ApneaLINK (AL) as an accurate tool for determining the presence of obstructive sleep apnea (OSA) in an at-risk sleep clinic population in a home test environment.
  
  
  METHODS
  Consecutive participants referred with the suspicion of OSA were evaluated in the home with the AL portable monitor (AL Home), followed by simultaneous data collection with diagnostic polysomnography (PSG) and AL in the sleep laboratory (AL Lab). Prevalence, sensitivity, specificity, and ROC curves were calculated for PSG vs. AL Lab, PSG vs. AL Home, and AL Lab vs. AL Home test. Pearson correlations and Bland-Altman plots were constructed.
  
  
  RESULTS
  Fifty-three (55% female) participants completed the entire study. The mean age of the population was 45.1 ± 11.3 years, and body mass index was 35.9 ± 9.1 kg/m(2). The prevalence of an apnea hypopnea index (AHI) ≥ 15 in the cohort was 35.9%. The results demonstrated a high sensitivity and specificity of the AL respiratory disturbance index (RDI-AL) compared with the AHI from the PSG. The AL Lab had the highest sensitivity and specificity at RDI-AL values ≥ 20 events/h (sensitivity 100%, specificity 92.5%). The AL Home was most sensitive and specific at an RDI-AL ≥ 20 events/h (sensitivity 76.9%, specificity 92.5%). The Pearson correlations for PSG vs. AL Lab and PSG vs. AL Home were ρ = 0.88 and ρ = 0.82, respectively. The Bland-Altman Plots demonstrated good agreement between the methodologies.
  
  
  CONCLUSIONS
  The AL home test is an accurate alternative to PSG in sleep clinic populations at risk for moderate and severe OSA.
  
  
  BACKGROUND
  clinicaltrials.gov ID: NCT00354614.
authors: UPMC Sleep Medicine Center, Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
authors: Burcu
authors: B
authors: Oktay
authors: Thomas B
authors: TB
authors: Rice
authors: Charles W
authors: CW
authors: Atwood
authors: Michael
authors: M
authors: Passero
authors: Neeraj
authors: N
authors: Gupta
authors: Rachel
authors: R
authors: Givelber
authors: Oliver J
authors: OJ
authors: Drumheller
authors: Patricia
authors: P
authors: Houck
authors: Nancy
authors: N
authors: Gordon
authors: Patrick J
authors: PJ
authors: Strollo
mesh_terms: D000328:Adult; D015331:Cohort Studies; D004867:Equipment Design; D004869:Equipment Safety; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D018670:Monitoring, Ambulatory / Q000295:instrumentation* / Q000379:methods; D008991:Monitoring, Physiologic / Q000295:instrumentation*; D017286:Polysomnography / Q000379:methods; D011446:Prospective Studies; D012372:ROC Curve; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index; D020181:Sleep Apnea, Obstructive / Q000175:diagnosis*