title: Degradation of ochratoxin a by Brevibacterium species.
abstract: The ability to degrade ochratoxin A was studied in different bacteria with a well-known capacity to transform aromatic compounds. Strains belonging to Rhodococcus, Pseudomonas, and Brevibacterium genera were grown in liquid synthetic culture medium containing ochratoxin A. Brevibacterium spp. strains showed 100% degradation of ochratoxin A. Ochratoxin α was detected and identified by high-performance liquid chromatography-mass spectrometry (HPLC-MS) as a degradation product in the cell-free supernatants. The degradation of ochratoxin A is of public concern for food and environmental safety, because it could contribute to the development of new biological ochratoxin A detoxification systems in foodstuffs. In this study, the degradation of ochratoxin A by bacteria belonging to the food chain was demonstrated for the first time.
authors: Lab. Biotecnología Bacteriana, Instituto de Ciencia y Tecnología de Alimentos y Nutrición (ICTAN) , CSIC, Juan de la Cierva 3, 28006 Madrid, Spain.
authors: Hector
authors: H
authors: Rodriguez
authors: Ines
authors: I
authors: Reveron
authors: Francesca
authors: F
authors: Doria
authors: Antonella
authors: A
authors: Costantini
authors: Blanca
authors: B
authors: De Las Rivas
authors: Rosario
authors: R
authors: Muňoz
authors: Emilia
authors: E
authors: Garcia-Moruno
mesh_terms: D001673:Biodegradation, Environmental; D001951:Brevibacterium / Q000378:metabolism*; D002851:Chromatography, High Pressure Liquid; D005506:Food Contamination / Q000032:analysis / Q000517:prevention & control; D013058:Mass Spectrometry; D009183:Mycotoxins / Q000378:metabolism*; D009793:Ochratoxins / Q000032:analysis / Q000378:metabolism*; D011042:Poisons / Q000378:metabolism
chemical_list: D009183:Mycotoxins; D009793:Ochratoxins; D011042:Poisons; C025589:ochratoxin A