title: [Determination of Hg in biological samples by inductively coupled plasma mass spectrometry].
abstract: OBJECTIVE
  To establish an inductively coupled plasma mass spectrometry (ICP-MS) method for determination of Hg in biological samples.
  
  
  METHODS
  The samples were digested with microwave digestion instrument. ICP-MS was applied to detect Hg in blood, urine and hair specimens by using 115In as an internal marker. The ability of gold to eliminate the memory effect of mercury was investigated with the gold amalgamate produced by gold and mercury.
  
  
  RESULTS
  The limits of detection were in the 0.01 microg/L, and the accuracy of the method ranged from 97.0% to 107.1%. The concentration of gold was 10 microg/L and the memory effect of mercury was resolved.
  
  
  CONCLUSIONS
  The method is accurate, rapid, sensitive and suitable for the cases of mercury poisoning and the clinical diagnosis and monitoring for patients with mercury poisoning.
authors: Department of Forensic Medicine, Shanghai Medical College, Fudan University, Shanghai 200032, China. madong@ssfjd.cn
authors: Dong
authors: D
authors: Ma
authors: Dan
authors: D
authors: Zhang
authors: Xian-Yi
authors: XY
authors: Zhuo
authors: Wei
authors: W
authors: Liu
authors: Bao-Hua
authors: BH
authors: Shen
authors: Min
authors: M
authors: Shen
mesh_terms: D053593:Forensic Toxicology; D006197:Hair / Q000737:chemistry*; D006801:Humans; D007202:Indicators and Reagents; D013058:Mass Spectrometry / Q000379:methods*; D008628:Mercury / Q000032:analysis* / Q000097:blood / Q000652:urine; D008630:Mercury Poisoning / Q000175:diagnosis; D008872:Microwaves; D012015:Reference Standards; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013048:Specimen Handling / Q000379:methods
chemical_list: D007202:Indicators and Reagents; D008628:Mercury