title: Urinary level of CA19-9 as a tumor marker in urothelial carcinoma of the bladder.
abstract: To diagnose the urothelial carcinoma of the bladder by measuring CA19-9 level in the urine.
  
  
  
  This study was conducted on 47 patients with histopathologically confirmed urothelial cancer and 50 control subjects. The urinary level of CA19-9 was measured in both groups by enzyme-linked immunosorbent assay after concentration of urine with Bio-Gel dry beads. Urine cytology was also done in both controls and patients.
  
  
  
  The mean urinary level of CA19-9 was 194.59 ± 110.56 u/mL in patients and 11.67 ± 8.42 u/mL in controls (P = .0001). The mean urinary level of CA19-9 in patients with low-grade and high-grade bladder cancer was 206.56 ± 114.56 u/mL and 174.80 ± 94.06 u/mL, respectively (P = .56). Urine cytology by Papanicolaou stain was mostly negative.
  
  
  
  It can be concluded that CA19-9 may be a useful non-invasive test to diagnose the urothelial carcinoma of the bladder.
authors: Department of Biochemistry, IPGME & R, 244-AJC, Bose Road, Kolkata, 700020, West Bengal, India. pal.keya@gmail.com
authors: Keya
authors: K
authors: Pal
authors: Suparna
authors: S
authors: Roy
authors: Samim Ali
authors: SA
authors: Mondal
authors: Uttara
authors: U
authors: Chatterjee
authors: Punit
authors: P
authors: Tiwari
authors: Malay
authors: M
authors: Bera
mesh_terms: D014408:Biomarkers, Tumor / Q000652:urine*; D018395:CA-19-9 Antigen / Q000652:urine*; D002295:Carcinoma, Transitional Cell / Q000175:diagnosis* / Q000652:urine*; D016022:Case-Control Studies; D006801:Humans; D008875:Middle Aged; D001749:Urinary Bladder Neoplasms / Q000175:diagnosis* / Q000652:urine*
chemical_list: D014408:Biomarkers, Tumor; D018395:CA-19-9 Antigen