title: Pyrophosphate-selective fluorescent chemosensor based on 1,8-naphthalimide-DPA-Zn(II) complex and its application for cell imaging.
abstract: A new zinc(II) complex with a two-dipicolylamine-substituted 1,8-naphthalimide for recognition of pyrophosphate with ratiometrical fluorescence changes in aqueous solution has been synthesized and characterized. Its biological application to monitor the intracellular pyrophosphate (PPi) was successfully demonstrated by the observation that the fluorescence of 1 was enhanced by the presence of the Zn(2+) ion and was quenched by addition of PPi.
authors: Department of Chemistry and Research Institute for Natural Sciences, Korea University, Seoul 136-701, Korea.
authors: Jun Feng
authors: JF
authors: Zhang
authors: Sooyeon
authors: S
authors: Kim
authors: Ji Hae
authors: JH
authors: Han
authors: Seung-Jea
authors: SJ
authors: Lee
authors: Tuhin
authors: T
authors: Pradhan
authors: Qian Yong
authors: QY
authors: Cao
authors: Suk Joong
authors: SJ
authors: Lee
authors: Chulhun
authors: C
authors: Kang
authors: Jong Seung
authors: JS
authors: Kim
mesh_terms: D000588:Amines / Q000737:chemistry*; D000818:Animals; D002460:Cell Line; D011756:Diphosphates / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000737:chemistry*; D051379:Mice; D008958:Models, Molecular; D015394:Molecular Structure; D053644:Naphthalimides / Q000737:chemistry*; D010848:Picolinic Acids / Q000737:chemistry*; D015032:Zinc / Q000737:chemistry*
chemical_list: C501847:2,2'-dipicolylamine; D000588:Amines; D011756:Diphosphates; D005456:Fluorescent Dyes; D053644:Naphthalimides; D010848:Picolinic Acids; D015032:Zinc