title: An unusual presentation of aggressive epithelial-myoepithelial carcinoma of the nasal cavity with high-grade histology.
abstract: BACKGROUND
  Epithelial-myoepithelial carcinoma is an uncommon, low-grade carcinoma that generally occurs in the salivary glands. A few cases of epithelial-myoepithelial carcinoma arising in the nasal cavity have been reported. We describe a unique case of aggressive epithelial-myoepithelial carcinoma in the nasal cavity.
  
  
  METHODS
  A 36-year-old woman presented with a mass in her left nasal cavity. Histopathological evaluation revealed it to be an epithelial-myoepithelial carcinoma with overt nuclear atypia, frequent mitoses and necrosis. The tumour recurred in the contralateral nasal cavity 15 months following primary excision. Medial maxillectomy and radiation therapy were performed. Seven-month follow up revealed extensive bone metastases.
  
  
  CONCLUSIONS
  We report a rare case of aggressive epithelial-myoepithelial carcinoma in the nasal cavity, with high-grade histology.
authors: Department of Otolaryngology-Head and Neck Surgery, College of Medicine, The Catholic University of Korea, Seoul, South Korea.
authors: J-O
authors: JO
authors: Park
authors: C-K
authors: CK
authors: Jung
authors: D-I
authors: DI
authors: Sun
authors: M-S
authors: MS
authors: Kim
mesh_terms: D000328:Adult; D001859:Bone Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary*; D002277:Carcinoma / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D005260:Female; D006652:Histological Techniques; D006801:Humans; D064847:Multimodal Imaging; D009208:Myoepithelioma / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D009296:Nasal Cavity / Q000473:pathology* / Q000601:surgery; D009669:Nose Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D049268:Positron-Emission Tomography; D014057:Tomography, X-Ray Computed