title: Regioselective copper-mediated synthesis of thieno[2,3-c]pyrane-7-one, indolo[2,3-c]pyrane-1-one, and indolo[3,2-c]pyrane-1-one.
abstract: In the presence of copper(I) iodide, heteroaromatic β-iodo-α,β-unsaturated carboxylic acid systems opposed to terminal alkyne afford selectively 6-endo-dig cyclization products via a tandem coupling oxacyclization reaction.
authors: Laboratoire de Physicochimie des Matériaux et des Biomolécules, EA 4244, Faculté des Sciences et Techniques de Tours, Parc de Grandmont, 37200 Tours, France.
authors: Samuel
authors: S
authors: Inack Ngi
authors: Vincent
authors: V
authors: Guilloteau
authors: Mohamed
authors: M
authors: Abarbri
authors: Jérôme
authors: J
authors: Thibonnet
mesh_terms: D000480:Alkynes / Q000737:chemistry; D002264:Carboxylic Acids / Q000737:chemistry; D002384:Catalysis; D002626:Chemistry, Pharmaceutical / Q000379:methods*; D003300:Copper / Q000737:chemistry; D003500:Cyclization; D007211:Indoles / Q000138:chemical synthesis*; D007454:Iodides / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D011714:Pyrans / Q000138:chemical synthesis*; D013237:Stereoisomerism; D013876:Thiophenes / Q000138:chemical synthesis*
chemical_list: D000480:Alkynes; D002264:Carboxylic Acids; D007211:Indoles; D007454:Iodides; D011714:Pyrans; D013876:Thiophenes; D003300:Copper