title: Induced pluripotent stem cells from highly endangered species.
abstract: For some highly endangered species there are too few reproductively capable animals to maintain adequate genetic diversity, and extraordinary measures are necessary to prevent extinction. We report generation of induced pluripotent stem cells (iPSCs) from two endangered species: a primate, the drill, Mandrillus leucophaeus and the nearly extinct northern white rhinoceros, Ceratotherium simum cottoni. iPSCs may eventually facilitate reintroduction of genetic material into breeding populations.
authors: Center for Regenerative Medicine, Department of Chemical Physiology, The Scripps Research Institute, La Jolla, California, USA.
authors: Inbar Friedrich
authors: IF
authors: Ben-Nun
authors: Susanne C
authors: SC
authors: Montague
authors: Marlys L
authors: ML
authors: Houck
authors: Ha T
authors: HT
authors: Tran
authors: Ibon
authors: I
authors: Garitaonandia
authors: Trevor R
authors: TR
authors: Leonardo
authors: Yu-Chieh
authors: YC
authors: Wang
authors: Suellen J
authors: SJ
authors: Charter
authors: Louise C
authors: LC
authors: Laurent
authors: Oliver A
authors: OA
authors: Ryder
authors: Jeanne F
authors: JF
authors: Loring
mesh_terms: D000818:Animals; D056727:Endangered Species; D057026:Induced Pluripotent Stem Cells / Q000166:cytology*; D048528:Mandrillus; D010527:Perissodactyla; D013045:Species Specificity