title: [Retroperitoneal fibrosis associated with chronic use of ergotamine: report of one case].
abstract: Retroperitoneal fibrosis (RPF) associated with chronic use of ergotamine is a very rare disorder. We report a 45-year-old woman who presented with a RPf after using, almost daily for 23 years, ergotamine tartrate for migraine relief. FRP presented as a chronic inflammatory state, anemia, abdominal and lumbosacral pain and a hypogastric mass. A CT-Scan showed a periaortic mass and left hydronephrosis. A percutaneous biopsy was obtained and the patient was subjected to a surgical ureterolysis and tissue resection. The biopsy confirmed the presence of RPf. Due to persistent symptoms and increase in the volume of periaortic tissue, treatment with colchicine 1 mg/day and defazacort 30 mg/day was started, resulting in a rapid disappearance of symptoms, disappearance of inflammation and a significant reduction in the volume of the periaortic tissue. The patient remains in complete remission after 29 months of follow up.
authors: Servicio de Medicina Interna, Sección de Nefrología, Hospital Naval A. Nef, Viña del Mar, Chile. jvegastieb@gmail.com
authors: Jorge
authors: J
authors: Vega
authors: Helmuth
authors: H
authors: Goecke
authors: Mario
authors: M
authors: Santamarina
mesh_terms: D018712:Analgesics, Non-Narcotic / Q000008:administration & dosage / Q000009:adverse effects*; D003078:Colchicine / Q000627:therapeutic use; D004878:Ergotamine / Q000008:administration & dosage / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008875:Middle Aged; D008881:Migraine Disorders / Q000188:drug therapy; D011241:Prednisone / Q000627:therapeutic use; D012185:Retroperitoneal Fibrosis / Q000139:chemically induced* / Q000188:drug therapy; D013997:Time Factors
chemical_list: D018712:Analgesics, Non-Narcotic; D004878:Ergotamine; D003078:Colchicine; D011241:Prednisone