title: Dobutamine stress echocardiography assessment of myocardial contusion due to blunt impact in dogs.
abstract: We sought to investigate the role of two-dimensional stress echocardiography in the early assessment of myocardial contusion. For this purpose, 12 dogs, weighing 11.36 ± 1.50 kg, were selected and the myocardial contusion was experimentally induced. Two-dimensional dobutamine stress echocardiography (DSE) was used to detect abnormal myocardial motions segments at time phases of baseline and 0.5, 2, 4, and 8 h post-wounding. Finally, the above results were compared with pathological findings. The data show that after the dogs were induced to have severe myocardial contusion, 122 segments were found with abnormal myocardial wall motions at 0.5 h post-wounding, 133 segments at 2 h post-wounding, and 142 segments, each, at 4 h and 8 h post-wounding. The wall motion score (WMS) and wall motion score index (WMSI) increased (P < 0.001) as compared with the pre-impaction values. Considering the left ventricular axis view as the standard section, in the 60 segments examined by echocardiography, 54 segments were found to have wall motion abnormalities. Comparing with the results of pathological TTC staining, the sensitivity and specificity were found to be 100 and 66.6%, respectively. It was, therefore, concluded that two-dimensional DSE was a valuable technique in the early diagnosis of myocardial contusion due to its better sensitivity and specificity.
authors: Department of Ultrasound, Daping Hospital & Research Institute of Surgery, The Military Medical University, Chongqing, China.
authors: WenHua
authors: W
authors: Du
authors: XiuQin
authors: X
authors: Xiong
authors: WeiXiao
authors: W
authors: Yang
authors: Xiang
authors: X
authors: Wang
authors: Tao
authors: T
authors: Li
mesh_terms: D000818:Animals; D002316:Cardiotonic Agents; D003324:Coronary Artery Disease / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D004280:Dobutamine; D004285:Dogs; D025401:Echocardiography, Stress; D006439:Hemodynamics; D012680:Sensitivity and Specificity; D016277:Ventricular Function, Left / Q000502:physiology
chemical_list: D002316:Cardiotonic Agents; D004280:Dobutamine