title: Synthesis of phenanthridinones from N-methoxybenzamides and arenes by multiple palladium-catalyzed C-H activation steps at room temperature.
abstract: Many steps make light work: substituted phenanthridinones can be obtained with high regioselectivity and in very good yields by palladium-catalyzed cyclization reactions of N-methoxybenzamides with arenes. The reaction proceeds through multiple oxidative C-H activation and C-C/C-N formation steps in one pot at room temperature, and thus provides a simple method for generating bioactive phenanthridinones.
authors: Department of Chemistry, National Tsing Hua University, Hsinchu, Taiwan.
authors: Jaganathan
authors: J
authors: Karthikeyan
authors: Chien-Hong
authors: CH
authors: Cheng
mesh_terms: D002384:Catalysis; D006841:Hydrocarbons, Aromatic / Q000737:chemistry*; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*; D010616:Phenanthrenes / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism; D013696:Temperature
chemical_list: D006841:Hydrocarbons, Aromatic; D009942:Organometallic Compounds; D010616:Phenanthrenes; D010165:Palladium