title: New electrophilic addition of α-diazoesters with ketones for enantioselective C-N bond formation.
abstract: α-Diazoesters were discovered to be good electrophiles in a catalytic asymmetric α-functionalization of ketones for the first time. This reaction also provided a direct and efficient method for C-N bond formation with excellent yields (up to 98%) and enantioselectivities (up to 99% ee) under mild conditions. The application of the electrophilicity of α-diazoesters opens up a novel way to access the diversity of diazo chemistry.
authors: Key Laboratory of Green Chemistry and Technology, Ministry of Education, College of Chemistry, Sichuan University, Chengdu 610064, PR China.
authors: Wei
authors: W
authors: Li
authors: Xiaohua
authors: X
authors: Liu
authors: Xiaoyu
authors: X
authors: Hao
authors: Xiaolei
authors: X
authors: Hu
authors: Yangyang
authors: Y
authors: Chu
authors: Weidi
authors: W
authors: Cao
authors: Song
authors: S
authors: Qin
authors: Changwei
authors: C
authors: Hu
authors: Lili
authors: L
authors: Lin
authors: Xiaoming
authors: X
authors: Feng