title: A case of haemophagocytic syndrome in HIV-associated disseminated histoplasmosis.
abstract: Disseminated histoplasmosis is an opportunistic infection which is commonly associated with HIV. Haemophagocytic lymphohistiocytosis (HLH) has been described as a secondary phenomenon to infection, collagen-vascular disorders and malignancies. In patients with HIV, cases of reactive haemophagocytic syndrome associated with disseminated histoplasmosis have been reported with CD4 counts of less than 50 cells/µl (450-1660 cells/µl). We report a case of a 25 year old man with HIV who presented with a CD4 count of 153 cells/µl and would suggest that this diagnosis should be considered at higher CD4 counts than previously reported.
authors: Chelsea and Westminster Hospital, London, UK. nvaid07@gmail.com
authors: Nidhi
authors: N
authors: Vaid
authors: Parind
authors: P
authors: Patel
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000150:complications / Q000175:diagnosis*; D000328:Adult; D018791:CD4 Lymphocyte Count; D015658:HIV Infections / Q000276:immunology; D006660:Histoplasmosis / Q000150:complications / Q000175:diagnosis*; D006801:Humans; D051359:Lymphohistiocytosis, Hemophagocytic / Q000150:complications / Q000175:diagnosis*; D008297:Male