title: Modeling of oleaginous fungal biofilm developed on semi-solid media.
abstract: An oleaginous fungus, Mortierella isabellina, able to transform efficiently sugar to storage lipid, was used as a model microorganism which develops a biofilm structure during the semi-solid fermentation process for the production of biodiesel from sweet sorghum. A mathematical model was developed to describe the fungal oil production in M. isabellina biofilm. The model describes diffusion and consumption of sugars and nitrogen of sweet sorghum and single cell oil production in a biofilm, which grows according to the kinetics of double-substrate limitation (sugars and nitrogen) with sugar inhibition. Experimental data from a previous experimental study were used to determine the kinetic parameters of the model. Maximum biofilm thickness and the percentage of lipid inside the biofilm were estimated using the model at 1892 μm and 15%, respectively. The proposed mathematical model could prove a useful tool for designing semi-solid fermentation processes.
authors: Department of Environmental and Natural Resources Management, University of Ioannina, G. Seferi 2, 30100 Agrinio, Greece.
authors: Ch N
authors: ChN
authors: Economou
authors: I A
authors: IA
authors: Vasiliadou
authors: G
authors: G
authors: Aggelis
authors: S
authors: S
authors: Pavlou
authors: D V
authors: DV
authors: Vayenas
mesh_terms: D018441:Biofilms; D050260:Carbohydrate Metabolism; D004058:Diffusion; D005285:Fermentation; D007700:Kinetics; D008962:Models, Theoretical; D020094:Mortierella / Q000378:metabolism*