title: Prevalence of medication administration errors in two medical units with automated prescription and dispensing.
abstract: OBJECTIVE
  To identify the frequency of medication administration errors and their potential risk factors in units using a computerized prescription order entry program and profiled automated dispensing cabinets.
  
  
  METHODS
  Prospective observational study conducted within two clinical units of the Gastroenterology Department in a 1537-bed tertiary teaching hospital in Madrid (Spain).
  
  
  METHODS
  Medication errors were measured using the disguised observation technique. Types of medication errors and their potential severity were described. The correlation between potential risk factors and medication errors was studied to identify potential causes.
  
  
  RESULTS
  In total, 2314 medication administrations to 73 patients were observed: 509 errors were recorded (22.0%)-68 (13.4%) in preparation and 441 (86.6%) in administration. The most frequent errors were use of wrong administration techniques (especially concerning food intake (13.9%)), wrong reconstitution/dilution (1.7%), omission (1.4%), and wrong infusion speed (1.2%). Errors were classified as no damage (95.7%), no damage but monitoring required (2.3%), and temporary damage (0.4%). Potential clinical severity could not be assessed in 1.6% of cases. The potential risk factors morning shift, evening shift, Anatomical Therapeutic Chemical medication class antacids, prokinetics, antibiotics and immunosuppressants, oral administration, and intravenous administration were associated with a higher risk of administration errors. No association was found with variables related to understaffing or nurse's experience.
  
  
  CONCLUSIONS
  Medication administration errors persist in units with automated prescription and dispensing. We identified a need to improve nurses' working procedures and to implement a Clinical Decision Support tool that generates recommendations about scheduling according to dietary restrictions, preparation of medication before parenteral administration, and adequate infusion rates.
authors: Department of Pharmacy, Hospital General Universitario Gregorio Marañón, Madrid, Spain. crodriguezg.hgugm@salud.madrid.org
authors: Carmen Guadalupe
authors: CG
authors: Rodriguez-Gonzalez
authors: Ana
authors: A
authors: Herranz-Alonso
authors: Maria Luisa
authors: ML
authors: Martin-Barbero
authors: Esther
authors: E
authors: Duran-Garcia
authors: Maria Isabel
authors: MI
authors: Durango-Limarquez
authors: Paloma
authors: P
authors: Hernández-Sampelayo
authors: Maria
authors: M
authors: Sanjurjo-Saez
mesh_terms: D005762:Gastroenterology; D006302:Health Services Research; D006748:Hospital Departments; D006757:Hospital Units; D006784:Hospitals, Teaching; D006801:Humans; D050316:Medical Order Entry Systems; D008508:Medication Errors / Q000706:statistics & numerical data*; D008510:Medication Systems, Hospital / Q000706:statistics & numerical data*; D013030:Spain