title: Ultrasonographic features of intrathyroidal parathyroid adenoma causing primary hyperparathyroidism.
abstract: Preoperative localization study is difficult in patients with primary hyperparathyroidism (PHPT) caused by intrathyroidal parathyroid adenoma.  The objective of this study was to evaluate the usefulness of ultrasonography (US) in the diagnosis of intrathyroidal parathyroid adenoma.  Between January 2004 and December 2009, seven of 373 patients who underwent parathyroidectomy because of PHPT in our hospital were found to have intrathyroidal parathyroid adenoma.  The ultrasonographic features of intrathyroidal parathyroid adenoma were examined retrospectively.  The most characteristic feature of intrathyroidal parathyroid adenoma was a hyperechoic line on the ventral surface of the parathyroid gland.  A hyperechoic line was clearly detected even in small adenomas in which feeding vessels could not be detected on color Doppler sonography.  In comparison with feeding vessels, a hyperechoic line was frequently detected in normally located parathyroid adenoma.  (99m)Tc-sestamibi (MIBI) scintigraphy and computed tomography (CT) could show parathyroid adenoma in the intrathyroidal position in only three of five and in only one of three patients examined, respectively.  Since a hyperechoic line is characteristic of parathyroid adenoma, an intrathyroidal parathyroid adenoma could be suspected by only non-invasive US.
authors: Department of Surgery, Kuma Hospital, Kobe 650-0011, Japan. yabuta@kuma-h.or.jp
authors: Tomonori
authors: T
authors: Yabuta
authors: Yukiko
authors: Y
authors: Tsushima
authors: Hiroo
authors: H
authors: Masuoka
authors: Chisato
authors: C
authors: Tomoda
authors: Mitsuhiro
authors: M
authors: Fukushima
authors: Minoru
authors: M
authors: Kihara
authors: Hiroyuki
authors: H
authors: Inoue
authors: Takuya
authors: T
authors: Higashiyama
authors: Yuuki
authors: Y
authors: Takamura
authors: Yasuhiro
authors: Y
authors: Ito
authors: Kaoru
authors: K
authors: Kobayashi
authors: Akihiro
authors: A
authors: Miya
authors: Akira
authors: A
authors: Miyauchi
mesh_terms: D000328:Adult; D000368:Aged; D016009:Chi-Square Distribution; D005260:Female; D006801:Humans; D006961:Hyperparathyroidism / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D008297:Male; D008875:Middle Aged; D010282:Parathyroid Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D011877:Radionuclide Imaging; D012189:Retrospective Studies; D017256:Technetium Tc 99m Sestamibi; D013964:Thyroid Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D014057:Tomography, X-Ray Computed; D018615:Ultrasonography, Doppler, Color
chemical_list: D017256:Technetium Tc 99m Sestamibi