title: Survey of polyphenol constituents in grapes and grape-derived products.
abstract: A rapid and comprehensive qualitative method has been developed to characterize the different classes of polyphenols, such as anthocyanins, flavonols, phenolic acids, and flavanols/proanthocyanidins, in grape products. The detection was achieved by two runs with the same LC gradient in different MS ionization modes and mobile phase modifiers (positive ionization mode and 0.4% trifluoroacetic acid for anthocyanins and flavonols; negative ionization mode and 0.1% formic acid for phenolic acids and flavanols). From an analysis of the MS and UV data and in comparison with the authenticated standards, a total of 53 compounds were identified, including 33 anthocyanins, 12 flavonols, 4 phenolic acids, and 4 flavanols/proanthocyanidins. With the method developed, a survey was then conducted to qualitatively assess the composition of polyphenols among 29 different grape products including original grape, grape juice, grape wine, and grape-derived dietary supplements, and their chemical profiles were systematically compared. This method provided a comprehensive qualitative insight into the composition of polyphenols in grape-derived products.
authors: New Use Agriculture and Natural Plant Products Program, Department of Plant Biology and Pathology, Rutgers University , 59 Dudley Road, New Brunswick, New Jersey 08901, United States.
authors: Yanping
authors: Y
authors: Xu
authors: James E
authors: JE
authors: Simon
authors: Cara
authors: C
authors: Welch
authors: Jolynne D
authors: JD
authors: Wightman
authors: Mario G
authors: MG
authors: Ferruzzi
authors: Lap
authors: L
authors: Ho
authors: Giulio M
authors: GM
authors: Pasinetti
authors: Guilio M
authors: GM
authors: Passinetti
authors: Qingli
authors: Q
authors: Wu
mesh_terms: D000872:Anthocyanins / Q000032:analysis; D001628:Beverages / Q000032:analysis; D002851:Chromatography, High Pressure Liquid; D005419:Flavonoids / Q000032:analysis; D005638:Fruit / Q000737:chemistry*; D062385:Hydroxybenzoates / Q000032:analysis; D013058:Mass Spectrometry; D059808:Polyphenols / Q000032:analysis*; D012639:Seeds / Q000737:chemistry; D027843:Vitis / Q000737:chemistry*; D014920:Wine / Q000032:analysis
chemical_list: D000872:Anthocyanins; D005419:Flavonoids; D062385:Hydroxybenzoates; D059808:Polyphenols; C017616:phenolic acid