title: Identifying influential observations in Bayesian models by using Markov chain Monte Carlo.
abstract: In statistical modelling, it is often important to know how much parameter estimates are influenced by particular observations. An attractive approach is to re-estimate the parameters with each observation deleted in turn, but this is computationally demanding when fitting models by using Markov chain Monte Carlo (MCMC), as obtaining complete sample estimates is often in itself a very time-consuming task. Here we propose two efficient ways to approximate the case-deleted estimates by using output from MCMC estimation. Our first proposal, which directly approximates the usual influence statistics in maximum likelihood analyses of generalised linear models (GLMs), is easy to implement and avoids any further evaluation of the likelihood. Hence, unlike the existing alternatives, it does not become more computationally intensive as the model complexity increases. Our second proposal, which utilises model perturbations, also has this advantage and does not require the form of the GLM to be specified. We show how our two proposed methods are related and evaluate them against the existing method of importance sampling and case deletion in a logistic regression analysis with missing covariates. We also provide practical advice for those implementing our procedures, so that they may be used in many situations where MCMC is used to fit statistical models.
authors: MRC Biostatistics Unit, Cambridge, UK. daniel.jackson@mrc-bsu.cam.ac.uk
authors: Dan
authors: D
authors: Jackson
authors: Ian R
authors: IR
authors: White
authors: James
authors: J
authors: Carpenter
mesh_terms: D001499:Bayes Theorem; D016022:Case-Control Studies; D003198:Computer Simulation / Q000706:statistics & numerical data; D006801:Humans; D007223:Infant; D008390:Markov Chains; D015233:Models, Statistical; D009010:Monte Carlo Method; D012044:Regression Analysis; D013398:Sudden Infant Death / Q000453:epidemiology