title: Beneficial effects of physical activity in an HIV-infected woman with lipodystrophy: a case report.
abstract: BACKGROUND
  Lipodystrophy is common in patients infected with human immunodeficiency virus receiving highly active antiretroviral therapy, and presents with morphologic changes and metabolic alterations that are associated with depressive behavior and reduced quality of life. We examined the effects of exercise training on morphological changes, lipid profile and quality of life in a woman with human immunodeficiency virus presenting with lipodystrophy.
  
  
  METHODS
  A 31-year-old Latin-American Caucasian woman infected with human immunodeficiency virus participated in a 12-week progressive resistance exercise training program with an aerobic component. Her weight, height, skinfold thickness, body circumferences, femur and humerus diameter, blood lipid profile, maximal oxygen uptake volume, exercise duration, strength and quality of life were assessed pre-exercise and post-exercise training. After 12 weeks, she exhibited reductions in her total subcutaneous fat (18.5%), central subcutaneous fat (21.0%), peripheral subcutaneous fat (10.7%), waist circumference (WC) (4.5%), triglycerides (9.9%), total cholesterol (12.0%) and low-density lipoprotein cholesterol (8.6%). She had increased body mass (4.6%), body mass index (4.37%), humerus and femur diameter (3.0% and 2.3%, respectively), high-density lipoprotein cholesterol (16.7%), maximal oxygen uptake volume (33.3%), exercise duration (37.5%) and strength (65.5%). Quality of life measures improved mainly for psychological and physical measures, independence and social relationships.
  
  
  CONCLUSIONS
  These findings suggest that supervised progressive resistance exercise training is a safe and effective treatment for evolving morphologic and metabolic disorders in adults infected with HIV receiving highly active antiretroviral therapy, and improves their quality of life.
authors: Programa de Pós-Graduação em Biologia Celular e Estrutural, Laboratório de Imunovirologia Molecular, Universidade Federal de Viçosa/MG, Brasil. edmar.mendes@ufv.br.
authors: Edmar Lacerda
authors: EL
authors: Mendes
authors: Alynne Christian
authors: AC
authors: Ribeiro Andaki
authors: Ciro José
authors: CJ
authors: Brito
authors: Cláudio
authors: C
authors: Córdova
authors: Antônio José
authors: AJ
authors: Natali
authors: Paulo Roberto Dos
authors: PR
authors: Santos Amorim
authors: Leandro Licursi
authors: LL
authors: de Oliveira
authors: Sérgio Oliveira
authors: SO
authors: de Paula
authors: Eugene
authors: E
authors: Mutimura