title: Mannose-binding lectin (MBL2) polymorphisms and inflammation in hypertensive patients.
abstract: We investigated the possible role of Mannose binding lectin 2 (MBL2) functional polymorphisms in the prevalence of hypertension and hypertensive end-organ damage in 300 hypertensive patients and 313 normotensive individuals from Southern Brazil. Hypertensive subjects with MBL2 AO/OO genotypes presented lower C-reactive protein levels than AA individuals and consequently lower inflammatory status.
authors: Department of Internal Medicine, University of Campinas, Campinas, Brazil.
authors: R
authors: R
authors: Schreiber
authors: A V
authors: AV
authors: Campos-Coelho
authors: L
authors: L
authors: Brandão
authors: R L
authors: RL
authors: Guimarães
authors: A J
authors: AJ
authors: Kamada
authors: M C
authors: MC
authors: Ferreira-Sae
authors: J R
authors: JR
authors: Matos-Souza
authors: J A
authors: JA
authors: Cipolli
authors: J L
authors: JL
authors: de Lima-Filho
authors: S
authors: S
authors: Crovella
authors: W
authors: W
authors: Nadruz
mesh_terms: D001938:Brazil; D002097:C-Reactive Protein / Q000378:metabolism; D005260:Female; D020022:Genetic Predisposition to Disease; D006801:Humans; D006973:Hypertension / Q000150:complications* / Q000235:genetics*; D007249:Inflammation / Q000150:complications* / Q000235:genetics*; D008297:Male; D037601:Mannose-Binding Lectin / Q000235:genetics*; D008875:Middle Aged; D020641:Polymorphism, Single Nucleotide / Q000235:genetics*
chemical_list: C445619:MBL2 protein, human; D037601:Mannose-Binding Lectin; D002097:C-Reactive Protein