title: [The phylogenetic position of Chlamydia strains isolated from monkeys and humans with Chlamydial pathology in the family Chiamydiaceae. Genotypic and phenotypic properties of this pathogen].
abstract: Based on the results of the comparative analysis concerning relatedness and evolutional difference of the 16S - 23S nucleotide sequences of the middle ribosomal cluster and 23S rRNA I domain, and based on identification of phylogenetic position for Chlamydophila pneumoniae and Chlamydia trichomatis strains released from monkeys, relatedness of the above stated isolates with similar strains released from humans and with strains having nucleotide sequences presented in the GenBank electronic database has been detected for the first time ever. Position of these isolates in the Chlamydiaceae family phylogenetic tree has been identified. The evolutional position of the investigated original Chlamydia and Chlamydophila strains close to analogous strains from the GenBank electronic database has been demonstrated. Differences in the 16S - 23S nucleotide sequence of the middle ribosomal cluster and 23S rRNA I domain of plasmid and non-plasmid Chlamydia trachomatis strains released from humans and monkeys relative to different genotype groups (group B- B, Ba, D, Da, E, L1, L2, L2a; intermediate group - F, G, Ga) have been revealed for the first time ever. Abnormality in incA chromosomal gene expression resulting in Chlamydia life and development cycle disorder and decrease of Chlamydia virulence can be related to probable changes in the nucleotide sequence of the gene under consideration.
authors: A V
authors: AV
authors: Karaulov
authors: V V
authors: VV
authors: Slobodeniuk
authors: V A
authors: VA
authors: Aleshkin
authors: O G
authors: OG
authors: Grechishnikova
authors: S S
authors: SS
authors: Afanas'ev
authors: B A
authors: BA
authors: Lapin
authors: É K
authors: ÉK
authors: Dzhikidze
authors: Iu V
authors: IuV
authors: Nesvizhskiĭ
authors: E A
authors: EA
authors: Voropaeva
authors: M S
authors: MS
authors: Afanas'ev
authors: A V
authors: AV
authors: Aleshkin
authors: V A
authors: VA
authors: Metel'skaia
authors: E A
authors: EA
authors: Egorova
authors: A L
authors: AL
authors: Baĭrakova
mesh_terms: D000818:Animals; D001483:Base Sequence; D002692:Chlamydia trachomatis / Q000145:classification / Q000235:genetics* / Q000472:pathogenicity; D023521:Chlamydophila Infections / Q000235:genetics* / Q000382:microbiology; D016993:Chlamydophila pneumoniae / Q000145:classification / Q000235:genetics* / Q000472:pathogenicity; D019143:Evolution, Molecular; D000882:Haplorhini; D006801:Humans; D008969:Molecular Sequence Data; D009690:Nucleic Acid Conformation; D012336:RNA, Ribosomal, 16S; D012338:RNA, Ribosomal, 23S; D016415:Sequence Alignment; D012689:Sequence Homology, Nucleic Acid
chemical_list: D012336:RNA, Ribosomal, 16S; D012338:RNA, Ribosomal, 23S