title: Relationships between menopausal and mood symptoms and EEG sleep measures in a multi-ethnic sample of middle-aged women: the SWAN sleep study.
abstract: OBJECTIVE
  Examine associations of vasomotor and mood symptoms with visually scored and computer-generated measures of EEG sleep.
  
  
  METHODS
  Cross-sectional analysis.
  
  
  METHODS
  Community-based in-home polysomnography (PSG).
  
  
  METHODS
  343 African American, Caucasian, and Chinese women; ages 48-58 years; pre-, peri- or post-menopausal; participating in the Study of Women's Health Across the Nation Sleep Study (SWAN Sleep Study).
  
  
  METHODS
  None.
  
  
  RESULTS
  Measures included PSG-assessed sleep duration, continuity, and architecture, delta sleep ratio (DSR) computed from automated counts of delta wave activity, daily diary-assessed vasomotor symptoms (VMS), questionnaires to collect mood (depression, anxiety) symptoms, medication, and lifestyle information, and menopausal status using bleeding criteria. Sleep outcomes were modeled using linear regression. Nocturnal VMS were associated with longer sleep time. Higher anxiety symptom scores were associated with longer sleep latency and lower sleep efficiency, but only in women reporting nocturnal VMS. Contrary to expectations, VMS and mood symptoms were unrelated to either DSR or REM latency.
  
  
  CONCLUSIONS
  Vasomotor symptoms moderated associations of anxiety with EEG sleep measures of sleep latency and sleep efficiency and was associated with longer sleep duration in this multi-ethnic sample of midlife women.
authors: Department of Psychiatry and 2Department of Preventive Medicine, Rush University Medical Center, Chicago, IL 60612, USA. hkravitz@rush.edu
authors: Howard M
authors: HM
authors: Kravitz
authors: Elizabeth
authors: E
authors: Avery
authors: Maryfran
authors: M
authors: Sowers
authors: Joyce T
authors: JT
authors: Bromberger
authors: Jane F
authors: JF
authors: Owens
authors: Karen A
authors: KA
authors: Matthews
authors: Martica
authors: M
authors: Hall
authors: Huiyong
authors: H
authors: Zheng
authors: Ellen B
authors: EB
authors: Gold
authors: Daniel J
authors: DJ
authors: Buysse
mesh_terms: D001741:Black or African American; D044466:Asian People; D003430:Cross-Sectional Studies; D004569:Electroencephalography; D005260:Female; D006801:Humans; D008593:Menopause / Q000208:ethnology / Q000502:physiology*; D008875:Middle Aged; D019964:Mood Disorders / Q000208:ethnology* / Q000503:physiopathology; D017286:Polysomnography; D012893:Sleep Wake Disorders / Q000208:ethnology* / Q000503:physiopathology; D014666:Vasomotor System / Q000503:physiopathology; D044465:White People