title: No evidence for a role of xenotropic murine leukaemia virus-related virus and BK virus in prostate cancer of German patients.
abstract: Prostate cancer is one of the most prevalent types of cancer in men. Controversial data exist concerning the role of BKPyV and the xenotropic murine leukaemia virus-related gammaretrovirus (XMRV) in prostate cancer development. We therefore assessed the association between prostate cancer and viral infections. We could detect BKPyV in only 1 out of 85 prostate cancer samples, whereas none of the tissue samples showed evidence for XMRV positivity. Lack of detection of BKPyV and XMRV in prostate cancer tissues suggests that these viruses do not play a role in the pathogenesis of this type of cancer.
authors: Institute of Virology, National Reference Center for Papillomaviruses and Polyomaviruses, University of Cologne, Fürst-Pückler-Str. 56, 50935, Cologne, Germany.
authors: Baki
authors: B
authors: Akgül
authors: David
authors: D
authors: Pfister
authors: Ruth
authors: R
authors: Knüchel
authors: Axel
authors: A
authors: Heidenreich
authors: Ulrike
authors: U
authors: Wieland
authors: Herbert
authors: H
authors: Pfister
mesh_terms: D000328:Adult; D000368:Aged; D001739:BK Virus / Q000302:isolation & purification*; D005858:Germany / Q000453:epidemiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D027601:Polyomavirus Infections / Q000453:epidemiology* / Q000821:virology; D015995:Prevalence; D011471:Prostatic Neoplasms / Q000453:epidemiology* / Q000209:etiology* / Q000821:virology; D012192:Retroviridae Infections / Q000453:epidemiology* / Q000821:virology; D014412:Tumor Virus Infections / Q000453:epidemiology* / Q000821:virology; D058008:Xenotropic murine leukemia virus-related virus / Q000302:isolation & purification*