title: Hydration status of patients with end-stage renal disease after kidney transplantation.
abstract: BACKGROUND
  This study was carried out to estimate the modification of hydration status within the first three months of renal transplantation.
  
  
  METHODS
  Fifty patients who underwent a first kidney allograft were prospectively followed for three months after renal transplantation to assess hydration status by bioimpedance spectroscopy.
  
  
  RESULTS
  Two hours before the transplant procedure, 10/42 (23.8%) patients were overhydrated. Two days after surgery, 32/40 (80.0%) patients were overhydrated and at three months, 14/27 (51.9%) patients remained fluid-overloaded. Peritoneal dialysis (PD) patients had a lower hydration status (-0.60 L) than hemodialysis (HD) patients (0.70 L; p < 0.05) and better residual diuresis (41.7 vs. 8.3 mL/h for HD patients, p < 0.01). Compared with patients who had a delayed graft function (DGF) or a slow graft function (SGF), the immediate graft function (IGF) group had a better hydration status before transplantation (p = 0.031). At three months, 12/14 of the overhydrated patients had a creatinine clearance between 30 and 60 mL/min/1.73 m(2) .
  
  
  CONCLUSIONS
  Patients receiving a first kidney transplant frequently have a hydration disorder. Transplantation is associated with increased hydration status, which seems to persist if DGF or SGF occurs.
authors: Nephrology Department, CHU Clemenceau, Caen, France.
authors: Victor
authors: V
authors: Gueutin
authors: Maxence
authors: M
authors: Ficheux
authors: Valérie
authors: V
authors: Châtelet
authors: Angélique
authors: A
authors: Lecouf
authors: Patrick
authors: P
authors: Henri
authors: Bruno
authors: B
authors: Hurault de Ligny
authors: Jean-Philippe
authors: JP
authors: Ryckelynck
authors: Thierry
authors: T
authors: Lobbedez
mesh_terms: D000328:Adult; D001834:Body Water / Q000502:physiology*; D003404:Creatinine / Q000378:metabolism; D051799:Delayed Graft Function; D005260:Female; D005500:Follow-Up Studies; D005919:Glomerular Filtration Rate; D006084:Graft Rejection; D006085:Graft Survival / Q000502:physiology; D006801:Humans; D007676:Kidney Failure, Chronic / Q000503:physiopathology* / Q000628:therapy*; D007677:Kidney Function Tests; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D011446:Prospective Studies; D006435:Renal Dialysis; D012307:Risk Factors
chemical_list: D003404:Creatinine