title: Epidemiological characteristics of sarcoidosis patients in the city of Rio de Janeiro, Brazil.
abstract: OBJECTIVE
  To analyze the epidemiological characteristics of sarcoidosis patients in the city of Rio de Janeiro, Brazil.
  
  
  METHODS
  A descriptive, case-control study involving 100 sarcoidosis patients under outpatient treatment between 2008 and 2010 at the Pedro Ernesto University Hospital, located in the city of Rio de Janeiro, Brazil. The diagnosis of sarcoidosis was based on clinical, radiological, biochemical, and histopathological criteria.
  
  
  RESULTS
  There was a predominance of females in the 35-40 year age bracket (range, 7-69 years), who accounted for 65% of the sample, although there was a second peak at approximately 55 years of age. The most common symptom was dyspnea (in 47%), and the most common radiological findings were pulmonary and lymph node involvement (stage II; in 43%), followed by stage III (in 20%), stage I (in 19%), stage 0 (in 15%), and stage IV (in 3%). No pleural effusion or digital clubbing was observed at diagnosis. The tuberculin skin test was negative in 94 patients. Spirometric findings at diagnosis were normal in 61 patients; indicative of obstructive lung disease in 21; and indicative of restrictive lung disease in 18. The most common biopsy sites were the lungs (principally by bronchoscopy) and the skin, the diagnosis being confirmed by biopsy in 56% and 29% of the cases, respectively. Treatment with prednisone was initiated in 75% of the patients and maintained for more than 2 years in 19.7%.
  
  
  CONCLUSIONS
  This study corroborates the findings of previous studies regarding the epidemiological characteristics of sarcoidosis patients.
authors: Pedro Ernesto University Hospital, Rio de Janeiro State University School of Medical Sciences – Rio de Janeiro, Brazil.
authors: Vinicius
authors: V
authors: Lemos-Silva
authors: Paula Barroso
authors: PB
authors: Araújo
authors: Christiane
authors: C
authors: Lopes
authors: Rogério
authors: R
authors: Rufino
authors: Cláudia Henrique
authors: CH
authors: da Costa
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D001706:Biopsy; D001938:Brazil / Q000453:epidemiology; D016022:Case-Control Studies; D002648:Child; D002947:Cities / Q000453:epidemiology; D005260:Female; D006801:Humans; D015994:Incidence; D008168:Lung / Q000473:pathology; D008297:Male; D008875:Middle Aged; D012507:Sarcoidosis / Q000453:epidemiology* / Q000473:pathology / Q000628:therapy; D017565:Sarcoidosis, Pulmonary / Q000453:epidemiology / Q000473:pathology / Q000628:therapy; D055815:Young Adult