title: Hypothyroidism presenting as cardiac tamponade in Down syndrome.
abstract: Down syndrome is the commonest chromosomal anomaly. It is often associated with hypothyroidism, which may rarely present with cardiac tamponade as the earliest manifestation and prompt treatment with L-thyroxine is life saving. A six-month-old female child diagnosed as a case of Down syndrome presented with shortness of breathing for last 1 1/2 months. Facial dysmorphism, characteristic of Down syndrome was present. Echocardiography revealed large pericardial effusion and right ventricular diagnostic collapse. A case of Down syndrome with hypothyroidism and cardiac tamponade was kept in mind. She was treated with L-thyroxine and clinical status improved.
authors: Department of Paediatrics, Indira Gandhi Medical College, Shimla.
authors: Parveen
authors: P
authors: Bhardwaj
authors: V K
authors: VK
authors: Sharma
authors: Rajeev
authors: R
authors: Bhardwaj
mesh_terms: D002305:Cardiac Tamponade / Q000150:complications*; D004314:Down Syndrome / Q000150:complications*; D005260:Female; D006801:Humans; D007037:Hypothyroidism / Q000150:complications / Q000188:drug therapy / Q000209:etiology*; D007223:Infant; D013974:Thyroxine / Q000627:therapeutic use
chemical_list: D013974:Thyroxine