title: Bead-selected antitumor genetic cell vaccines.
abstract: Cancer vaccines have always been in the scope of gene therapy research. One of the most successful approaches has been working with genetically modified tumor cells. However, to become a clinical reality, tumor cells must suffer a long and risky process from the extraction from the patient to the reimplantation as a vaccine. In this work, we explain our group's approach to reduce the cell number required to achieve an immune response against a melanoma murine model, employing bead-selected B16 tumor cells expressing GM-CSF and B7.2.
authors: Gene Therapy Group, Dpto. Farmacologia, Fac. Medicina, Univ. Valencia, Valencia, España.
authors: Mj
authors: M
authors: Herrero
authors: Botella
authors: B
authors: R
authors: Algás
authors: A
authors: R
authors: Fm
authors: F
authors: Marco
authors: Sf
authors: S
authors: Aliño