title: Clinical review: Thinking outside the box--an iconoclastic view of current practice.
abstract: Many advances in medicine have been achieved through challenging established dogma with revolutionary thought and novel practices. Each and every specialty is reinvigorated by regular re-evaluation of processes and practices in the light of new evidence and fresh conceptualization. Challenge can galvanize fresh thinking and new approaches, yet may also reinforce and strengthen traditional paradigms if the prevailing orthodoxy is subsequently revalidated. This article is a synopsis of a roundtable meeting held in Brussels in March 2010 designed specifically to confront doctrine with reasoned scientific argument, and to propose new ideas for advancing critical care practices and outcomes.
authors: Bloomsbury Institute of Intensive Care Medicine, Department of Medicine, University College London, London WC1E 6BT, UK. m.singer@ucl.ac.uk
authors: Mervyn
authors: M
authors: Singer
authors: Michael A
authors: MA
authors: Matthay
mesh_terms: D002395:Catecholamines; D000075202:Contraindications; D003422:Critical Care; D003693:Delirium / Q000139:chemically induced; D019937:Diagnostic Techniques and Procedures; D055317:Evidence-Based Practice; D006126:Group Processes; D006801:Humans; D007362:Intensive Care Units; D016032:Randomized Controlled Trials as Topic; D012131:Respiratory Insufficiency / Q000628:therapy
chemical_list: D002395:Catecholamines