title: Azidomethyl-ruthenocene: facile synthesis of a useful metallocene derivative and its application in the 'click' labelling of biomolecules.
abstract: A convenient synthesis of azidomethyl-ruthenocene and its use in the covalent labelling of amino acids, peptides and a peptide nucleic acid (PNA) monomer derivative by Cu(I) catalyzed azide-alkyne coupling (Cu-AAC, "click chemistry") are described.
authors.affiliation: Lehrstuhl für Anorganische Chemie I, Bioanorganische Chemie, Fakultät für Chemie und Biochemie, Ruhr-Universität Bochum, Universitätsstr. 150, 44801, Bochum, Germany.
authors.forename: Malay
authors.initials: M
authors.lastname: Patra
authors.forename: Nils
authors.initials: N
authors.lastname: Metzler-Nolte
mesh_terms: D000480:Alkynes / Q000737:chemistry; D000596:Amino Acids / Q000737:chemistry; D001386:Azides / Q000737:chemistry; D057930:Click Chemistry / Q000379:methods*; D003300:Copper / Q000737:chemistry; D009942:Organometallic Compounds / Q000138:chemical synthesis*; D020135:Peptide Nucleic Acids / Q000737:chemistry; D010455:Peptides / Q000737:chemistry; D013194:Staining and Labeling / Q000379:methods
chemical_list: D000480:Alkynes; D000596:Amino Acids; D001386:Azides; D009942:Organometallic Compounds; D020135:Peptide Nucleic Acids; D010455:Peptides; C013108:metallocene; C016721:ruthenocene; D003300:Copper