title: Detection of Extended Spectrum β-lactamase Production Among Uropathogens.
abstract: BACKGROUND
  Detection of extended spectrum β-lactamase (ESBL) production among uropathogens is an important marker of endemicity.
  
  
  OBJECTIVE
  Intervention of this endemic transmission is important for the control of initial outbreak of ESBL producing organisms in a hospital or specialized unit of hospital.
  
  
  METHODS
  During the study period of one and a half months, 1,551 urine samples were processed for significant bacteriuria. Two hundred gram negative bacterial isolates were tested for ESBL production. Antimicrobial sensitivity pattern was ascertained for ESBL producing isolates.
  
  
  RESULTS
  ESBL production was seen in 36% of isolates. All the isolates were multidrug resistant with uniform sensitivity to imipenem.
  
  
  CONCLUSIONS
  This study reveals the significant prevalence of ESBL producing organisms in this north Indian tertiary care hospital. Constant revision of antibiotic policies with infection control interventions is suggested.
authors.affiliation: Department of Microbiology, Pt. B.D. Sharma Post Graduate Institute of Medical Sciences, Rohtak-124 001, Haryana, India.
authors.forename: Ritu
authors.initials: R
authors.lastname: Aggarwal
authors.forename: Uma
authors.initials: U
authors.lastname: Chaudhary
authors.forename: Rama
authors.initials: R
authors.lastname: Sikka