title: Transformation in mandibular imaging with sweep imaging with fourier transform magnetic resonance imaging.
abstract: OBJECTIVE
  Current imaging techniques are often suboptimal for the detection of mandibular invasion by squamous cell carcinoma. The aim of this study was to determine the feasibility of a magnetic resonance imaging (MRI)-based technique known as sweep imaging with Fourier transform (SWIFT) to visualize the structural changes of intramandibular anatomy during invasion.
  
  
  METHODS
  Descriptive case study.
  
  
  METHODS
  Tertiary academic institution.
  
  
  METHODS
  Patients with oral carcinoma who underwent segmental mandibulectomy.
  
  
  METHODS
  Two specimens from each patient were imaged using a 9.4-T Varian MRI system. The SWIFT images were correlated with histologic sections.
  
  
  RESULTS
  The SWIFT technique with in vitro specimens produced images with sufficient resolution (156-273 μm) and contrast to allow accurate depiction of tumor invasion of cortical and medullary bone. Both specimens had histopathologic evidence of mandibular invasion with tumor. A high degree of correlation was found between magnetic resonance images and histopathologic findings.
  
  
  CONCLUSIONS
  The SWIFT MRI offers 3-dimensional assessment of cortical and medullary bone in fine detail and excellent qualitative agreement with histopathologic findings. Imaging with the SWIFT MRI technique demonstrates great potential to identify mandibular invasion by oral carcinoma.
authors.affiliation: Department of Radiology, University of Minnesota, Minneapolis, 55455, USA. karag003@umn.edu
authors.forename: Ayse Tuba Karagulle
authors.initials: AT
authors.lastname: Kendi
authors.forename: Samir S
authors.initials: SS
authors.lastname: Khariwala
authors.forename: Jinjin
authors.initials: J
authors.lastname: Zhang
authors.forename: Djaudat S
authors.initials: DS
authors.lastname: Idiyatullin
authors.forename: Curtis A
authors.initials: CA
authors.lastname: Corum
authors.forename: Shalom
authors.initials: S
authors.lastname: Michaeli
authors.forename: Stefan E
authors.initials: SE
authors.lastname: Pambuccian
authors.forename: Michael
authors.initials: M
authors.lastname: Garwood
authors.forename: Bevan
authors.initials: B
authors.lastname: Yueh
mesh_terms: D000539:Alveolar Process / Q000473:pathology / Q000601:surgery; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D005240:Feasibility Studies; D005583:Fourier Analysis; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008334:Mandible / Q000473:pathology / Q000601:surgery; D008339:Mandibular Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D009062:Mouth Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D009361:Neoplasm Invasiveness; D012680:Sensitivity and Specificity