title: Analysis of fresh Mentha haplocalyx volatile components by comprehensive two-dimensional gas chromatography and high-resolution time-of-flight mass spectrometry.
abstract: Fresh Mentha haplocalyx is a well known traditional Chinese medicinal material (CMM) used in both China and America. This paper reports analysis of the volatile components of fresh Mentha haplocalyx by comprehensive two-dimensional gas chromatography (GCxGC) and high-resolution time-of-flight mass spectrometry (HR-TOF-MS), a combination that provides almost complete chemical separation with elemental composition determination of analytes. 163 ketones and terpenes, including menthol and menthone, were tentatively identified, including enantiomers. This study suggests that GCxGCxHR-TOF-MS is suitable for routine identification of target compounds and enantiomers in CMM.
authors.affiliation: Research Center of TCM Processing Technology, Zhejiang Chinese Medical University, Hangzhou, PR China.
authors.forename: Gang
authors.initials: G
authors.lastname: Cao
authors.forename: Qiyuan
authors.initials: Q
authors.lastname: Shan
authors.forename: Xiaomeng
authors.initials: X
authors.lastname: Li
authors.forename: Xiaodong
authors.initials: X
authors.lastname: Cong
authors.forename: Yun
authors.initials: Y
authors.lastname: Zhang
authors.forename: Hao
authors.initials: H
authors.lastname: Cai
authors.forename: Baochang
authors.initials: B
authors.lastname: Cai
mesh_terms: D002849:Chromatography, Gas / Q000379:methods*; D013058:Mass Spectrometry / Q000379:methods*; D027541:Mentha / Q000737:chemistry*; D055549:Volatile Organic Compounds / Q000032:analysis* / Q000302:isolation & purification
chemical_list: D055549:Volatile Organic Compounds