title: [The latest trend and prospects of development of influenza vaccine].
abstract: Vaccine is the most effective measure against influenza. Current vaccine production is based on chicken eggs and has limitation of scalability. In addition, adaptation of influenza viruses to chicken eggs during passages causes antigenic change of viruses and may reduce the efficiency of vaccination. On the contrary, cell-based vaccine production has advantages over egg-based vaccine production in terms of above mentioned points of view.
authors.affiliation: National Institute of Infectious Diseases.
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Harada
authors.forename: Shigeyuki
authors.initials: S
authors.lastname: Itamura
mesh_terms: D006801:Humans; D007252:Influenza Vaccines
chemical_list: D007252:Influenza Vaccines