title: Early to midterm results of cardiac surgery with concomitant pulmonary resection.
abstract: BACKGROUND
  We report our experience of cardiac surgery with concomitant pulmonary resection, based on analysis of the results.
  
  
  METHODS
  Eleven patients (1 woman, 10 men) underwent cardiac surgery simultaneously with pulmonary resection; ten of them through median sternotomy. The cancer pathology consisted of non-small cell carcinoma (n = 10), and benign teratoma (n = 1). All lung lesions were removed using a wedge resection. Cardiac procedures consisted of off-pump coronary artery bypass grafting (n = 4), aortic valve replacement (n = 3), mitral valve plasty (n = 2), total arch replacement (n = 1), and descending aorta replacement (n = 1). Lung wedge resections were performed after induction with protamine sulfate.
  
  
  RESULTS
  The mean follow-up period was 19 ± 11 months (2-34). There was no operative mortality and no major cardiac complications. Three patients underwent a subsequent lobectomy through lateral thoracotomy. There were two postoperative deaths: one was from an unknown cause, 8 months postoperatively and another was from a lung cancer recurrence, 9 months after surgery. There were two local recurrences, 9 months and 14 months, postoperatively. The mean cancer-free period was 17 ± 10 (2-32) months.
  
  
  CONCLUSIONS
  Rates of operative mortality and morbidity following cardiac surgery with concomitant pulmonary resection were favorable, and early to midterm results were acceptable.
authors.affiliation: Division of Cardiovascular and Thoracic Surgery, Shiga University of Medical Science, Otsu, Shiga, Japan. sohosoba@belle.shiga-med.ac.jp
authors.forename: Soh
authors.initials: S
authors.lastname: Hosoba
authors.forename: Jun
authors.initials: J
authors.lastname: Hanaoka
authors.forename: Tomoaki
authors.initials: T
authors.lastname: Suzuki
authors.forename: Noriyuki
authors.initials: N
authors.lastname: Takashima
authors.forename: Atsushi
authors.initials: A
authors.lastname: Kambara
authors.forename: Keiji
authors.initials: K
authors.lastname: Matsubayashi
authors.forename: Tohru
authors.initials: T
authors.lastname: Asai
mesh_terms: D000368:Aged; D002289:Carcinoma, Non-Small-Cell Lung / Q000401:mortality / Q000601:surgery*; D006348:Cardiac Surgical Procedures / Q000379:methods* / Q000401:mortality; D002318:Cardiovascular Diseases / Q000401:mortality / Q000601:surgery*; D015897:Comorbidity; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008175:Lung Neoplasms / Q000401:mortality / Q000601:surgery*; D008297:Male; D011013:Pneumonectomy / Q000379:methods* / Q000401:mortality; D011183:Postoperative Complications; D011479:Protamines / Q000008:administration & dosage; D015996:Survival Rate; D013724:Teratoma / Q000401:mortality / Q000601:surgery*; D013908:Thoracotomy / Q000379:methods / Q000401:mortality; D016896:Treatment Outcome
chemical_list: D011479:Protamines