title: [The immunomorphologic analysis of innervation of chromaffin paraganglian cells of the mammalian arteries and heart].
abstract: Innervation of chromaffin cells of paraganglia of the wall of mammalian large arterial vessels and heart (in rat, cat, and human) was studied by neuromorphological and immunohistochemical methods. There is established similarity in structure of specialized, "basket"-type nerve endings of the chromaffin cells (ChC) with pericellular nerve apparatuses of sympathetic and parasympathetic autonomic neurons. It is proposed to use immunohistochemical reaction for synaptophysin as method of selective detection of ChC of paraganglia and adrenal medulla. The conclusion is made that synaptophysin-positive terminals (SPPT) found on bodies of ChC and postganglionic neurons represent efferent, rather than afferent, synapses formed by myelinated axons of preganglionic fibers. It is suggested that ChC of paraganglia alongside with their characteristic endocrine function participate in complex mechanisms of chemoreceptor regulation of tissue homeostasis of mammalian blood vessels and heart.
authors.forename: E I
authors.initials: EI
authors.lastname: Chumasov
authors.forename: E S
authors.initials: ES
authors.lastname: Petrova
authors.forename: D E
authors.initials: DE
authors.lastname: Korzhevskiĭ
mesh_terms: D000313:Adrenal Medulla / Q000294:innervation; D000818:Animals; D001158:Arteries / Q000294:innervation*; D002415:Cats; D006352:Heart Ventricles / Q000294:innervation*; D006801:Humans; D007150:Immunohistochemistry; D010233:Paraganglia, Chromaffin / Q000378:metabolism / Q000648:ultrastructure*; D051381:Rats; D013045:Species Specificity; D016708:Synaptophysin / Q000378:metabolism
chemical_list: D016708:Synaptophysin