title: Localization of nonpalpable breast lesions.
abstract: The introduction of mammography screening and improvements in diagnostic tools resulted in a major increase of breast cancers detectable as small, nonpalpable lesions suitable for breast-conserving treatment. Accurate preoperative localization of these cancers is a necessity. Several methods are available for localization, of which wire-guided localization is considered the current gold standard. Promising techniques are radio-guided occult lesion localization, radioactive seed localization and ultrasound-guided surgery. In this article, an overview of the various localization techniques is provided, describing advantages, shortcomings and effectiveness.
authors.affiliation: Department of Surgery, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX, The Netherlands. e.l.postma@umcutrecht.nl
authors.forename: Emily L
authors.initials: EL
authors.lastname: Postma
authors.forename: Arjen J
authors.initials: AJ
authors.lastname: Witkamp
authors.forename: Maurice Aaj
authors.initials: MA
authors.lastname: van den Bosch
authors.forename: Helena M
authors.initials: HM
authors.lastname: Verkooijen
authors.forename: Richard
authors.initials: R
authors.lastname: van Hillegersberg
mesh_terms: D001940:Breast / Q000473:pathology*; D001941:Breast Diseases / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008327:Mammography