title: Synthesis and structural studies of a new class of quaternary ammonium salts, which are derivatives of cage adamanzane type aminal 1, 3, 6, 8-tetraazatricyclo[4.3.1.13,8]undecane (TATU).
abstract: BACKGROUND
  Novel mono N-alkyl quaternary ammonium salts (3a-f) were prepared using the Menschutkin reaction from the cage adamanzane type aminal 1,3,6,8-tetraazatricyclo[4.3.1.13,8]undecane (TATU) and alkyl iodides, such as methyl, ethyl, propyl, butyl, pentyl and hexyl iodide (2a-f), in dry acetonitrile at room temperature.
  
  
  RESULTS
  The structures of these new quaternary ammonium salts were established using various spectral and electrospray ionization mass spectrometry (ESI-MS) analyses. Compound (3b) was also analyzed using X-ray crystallography.
  
  
  CONCLUSIONS
  It was noted that alkyl chain length did not significantly affect the reaction because all employed alkyl iodide electrophiles reacted in a similar fashion with the aminal 1 to produce the corresponding mono N-quaternary ammonium salts, which were characterized by spectroscopic and analytical techniques.
authors.affiliation: Departamento de Química, Universidad Nacional de Colombia, Ciudad Universitaria, Carrera 30 No, 45-03, Bogotá D,C,, Colombia. ariverau@unal.edu.co.
authors.forename: Augusto
authors.initials: A
authors.lastname: Rivera
authors.forename: John
authors.initials: J
authors.lastname: Sadat-Bernal
authors.forename: Jaime
authors.initials: J
authors.lastname: Ríos-Motta
authors.forename: Michal
authors.initials: M
authors.lastname: Dušek
authors.forename: Lukáš
authors.initials: L
authors.lastname: Palatinus