title: Cu(2+)-selective fluorescent chemosensor based on coumarin and its application in bioimaging.
abstract: A new fluorescent sensor L1 based on coumarin was synthesized. It shows high sensitivity and selectivity toward Cu(2+) in aqueous solution. The complexation mode and corresponding quenching mechanism were elucidated by ESI-MS and DFT calculations. In addition, biological imaging studies have demonstrated that L1 can detect Cu(2+) in living cells.
authors.affiliation: Key Laboratory of Nonferrous Metals Chemistry and Resources Utilization of Gansu Province, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, 730000, PR China.
authors.forename: Liang
authors.initials: L
authors.lastname: Huang
authors.forename: Ju
authors.initials: J
authors.lastname: Cheng
authors.forename: Kefeng
authors.initials: K
authors.lastname: Xie
authors.forename: Pinxian
authors.initials: P
authors.lastname: Xi
authors.forename: Fengping
authors.initials: F
authors.lastname: Hou
authors.forename: Zhengpeng
authors.initials: Z
authors.lastname: Li
authors.forename: Guoqiang
authors.initials: G
authors.lastname: Xie
authors.forename: Yanjun
authors.initials: Y
authors.lastname: Shi
authors.forename: Hongyan
authors.initials: H
authors.lastname: Liu
authors.forename: Decheng
authors.initials: D
authors.lastname: Bai
authors.forename: Zhengzhi
authors.initials: Z
authors.lastname: Zeng
mesh_terms: D056831:Coordination Complexes / Q000138:chemical synthesis / Q000737:chemistry*; D003300:Copper / Q000737:chemistry*; D003374:Coumarins / Q000737:chemistry*; D018360:Crystallography, X-Ray; D005456:Fluorescent Dyes / Q000737:chemistry*; D056945:Hep G2 Cells; D006801:Humans; D006835:Hydrazones / Q000737:chemistry*; D018613:Microscopy, Confocal; D008968:Molecular Conformation
chemical_list: D056831:Coordination Complexes; D003374:Coumarins; D005456:Fluorescent Dyes; D006835:Hydrazones; D003300:Copper; C030123:coumarin