title: Risk factors of ascites after hepatectomy for patients with hepatocellular carcinoma and hepatitis B virus-associated cirrhosis.
abstract: OBJECTIVE
  To identify risk factors of postoperative ascites after hepatectomy for patients with hepatocellular carcinoma (HCC) and hepatitis B virus associated-cirrhosis.
  
  
  METHODS
  The data of 73 patients were reviewed in current study. Pre- and intra-operative variables were retrospectively analyzed using uni- and multi-variate analyses. The diagnostic accuracy of the predictors was evaluated by the receiver operating characteristics (ROC) analysis.
  
  
  RESULTS
  Indocyanine green retention rate at 15 minutes (ICGR15) >10%, tumor size >10cm, splenectomy, middle hepatic vein (MHV) resection, red blood cell (RBC) transfusion were risk factors in univariate analysis. However, only ICGR15 >10%, tumor size >10cm and RBC transfusion showed prognostic power in multivariate analysis. ROC analysis suggested the best cut-off value of risk factors was 2.
  
  
  CONCLUSIONS
  Our study indicated the postoperative ascites could be predicted by pre- and intra-operative variables. ICGR15 >10%, tumor size >10cm and RBC transfusion were independent risk factors for ascites after hepatectomy. Patients with two or more of the above-mentioned risk factors may suffer postoperative ascites after hepatectomy.
authors.affiliation: Sichuan University, Chengdu, China.
authors.forename: Li-ping
authors.initials: LP
authors.lastname: Chen
authors.forename: Chuan
authors.initials: C
authors.lastname: Li
authors.forename: Chuan
authors.initials: C
authors.lastname: Wang
authors.forename: Tian-fu
authors.initials: TF
authors.lastname: Wen
authors.forename: Lu-nan
authors.initials: LN
authors.lastname: Yan
authors.forename: Bo
authors.initials: B
authors.lastname: Li
mesh_terms: D000328:Adult; D001201:Ascites / Q000209:etiology*; D006528:Carcinoma, Hepatocellular / Q000175:diagnosis / Q000601:surgery* / Q000821:virology; D016009:Chi-Square Distribution; D002681:China; D005260:Female; D006498:Hepatectomy / Q000009:adverse effects*; D006509:Hepatitis B / Q000150:complications*; D006801:Humans; D008103:Liver Cirrhosis / Q000175:diagnosis / Q000601:surgery* / Q000821:virology; D008113:Liver Neoplasms / Q000175:diagnosis / Q000601:surgery* / Q000821:virology; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D012372:ROC Curve; D012189:Retrospective Studies; D018570:Risk Assessment; D012307:Risk Factors; D016896:Treatment Outcome