title: HIV/AIDS research conducted in the developing world and sponsored by the developed world: reporting of research ethics committee review in two countries.
abstract: We explored how often journal articles reporting HIV research sponsored by a developed country, but conducted in a developing country, mention research ethics committee (REC) approval from both countries, and what factors are involved. Of all such 2007 articles on Medline conducted in one of four developing countries (N = 154), only 52% mentioned such dual approval. Mention of dual vs. single approval was more likely among articles with ≥ 50% sponsor country authors, and the United States as the sponsor country. Also, dual approval was more likely among articles that mentioned informed consent and funding, had ≥ 50% sponsor country authors, were biomedical (vs. psychosocial), and appeared in journals adopting International Committee Medical Journal Editors (ICMJE) guidelines. Dual approval was thus obtained in only half of the articles and was associated with ethical and logistic issues, indicating the need for clearer and more universally accepted guidelines.
authors.affiliation: Columbia University College of Physicians & Surgeons & Mailman School of Public Health, 1051 Riverside Drive, New York, NY 10032, USA.
authors.forename: Lisa Judy
authors.initials: LJ
authors.lastname: Chin
authors.forename: Hoda
authors.initials: H
authors.lastname: Rifai-Bashjawish
authors.forename: Kelly
authors.initials: K
authors.lastname: Kleinert
authors.forename: Alexandra
authors.initials: A
authors.lastname: Saltman
authors.forename: Cheng-Shiun
authors.initials: CS
authors.lastname: Leu
authors.forename: Robert
authors.initials: R
authors.lastname: Klitzman
mesh_terms: D000163:Acquired Immunodeficiency Syndrome; D001319:Authorship; D015706:Bibliometrics; D035843:Biomedical Research / Q000941:ethics*; D019049:Developed Countries; D003906:Developing Countries; D035081:Editorial Policies; D028744:Ethics Committees, Research; D032984:Ethics, Research; D017408:Guidelines as Topic; D006678:HIV; D015658:HIV Infections; D006801:Humans; D007258:Informed Consent / Q000941:ethics; D007391:International Cooperation; D010506:Periodicals as Topic / Q000941:ethics* / Q000706:statistics & numerical data; D011643:Publishing / Q000941:ethics* / Q000706:statistics & numerical data; D014481:United States