title: Cross-reactivity in the Platelia™ Aspergillus enzyme immunoassay caused by blastomycosis.
abstract: It is well known that cross reactions with other fungal pathogens including Histoplasma capsulatum can occur with the use of the Platelia™ Aspergillus galactomannan assay. We report two patients with confirmed blastomycosis whose bronchoalveolar lavage (BAL) fluid tested positive for Aspergillus galactomannan despite no evidence of aspergillosis.
authors.affiliation: The University of Iowa, Iowa Methodist Medical Center, Des Moines, Iowa, USA.
authors.forename: Jon
authors.initials: J
authors.lastname: Van Der Veer
authors.forename: Roshan J
authors.initials: RJ
authors.lastname: Lewis
authors.forename: Amir M
authors.initials: AM
authors.lastname: Emtiazjoo
authors.forename: Stephen D
authors.initials: SD
authors.lastname: Allen
authors.forename: L Joseph
authors.initials: LJ
authors.lastname: Wheat
authors.forename: Chadi A
authors.initials: CA
authors.lastname: Hage
mesh_terms: D000368:Aged; D001228:Aspergillosis / Q000175:diagnosis; D001230:Aspergillus / Q000737:chemistry; D001759:Blastomycosis / Q000175:diagnosis*; D019411:Clinical Laboratory Techniques / Q000379:methods*; D003429:Cross Reactions; D005690:Galactose / Q000031:analogs & derivatives; D006801:Humans; D007124:Immunoenzyme Techniques / Q000379:methods*; D008297:Male; D008351:Mannans / Q000032:analysis; D009172:Mycology / Q000379:methods*
chemical_list: D008351:Mannans; C012990:galactomannan; D005690:Galactose