title: Combination of π-π stacking and electrostatic repulsion between carboxylic carbon nanoparticles and fluorescent oligonucleotides for rapid and sensitive detection of thrombin.
abstract: On the basis of simultaneous electrostatic repulsion and π-π stacking interactions of carboxylic carbon nanoparticles (cCNPs) with single-stranded DNA, a noncovalent assembly of cCNPs and fluorescent aptamers is reported for rapid, sensitive, and selective detection of thrombin.
authors.affiliation: State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, 410082, China.
authors.forename: Jinhua
authors.initials: J
authors.lastname: Liu
authors.forename: Jishan
authors.initials: J
authors.lastname: Li
authors.forename: Ying
authors.initials: Y
authors.lastname: Jiang
authors.forename: Sheng
authors.initials: S
authors.lastname: Yang
authors.forename: Weihong
authors.initials: W
authors.lastname: Tan
authors.forename: Ronghua
authors.initials: R
authors.lastname: Yang
mesh_terms: D000818:Animals; D052157:Aptamers, Nucleotide / Q000737:chemistry; D015374:Biosensing Techniques / Q000379:methods*; D002244:Carbon / Q000737:chemistry*; D002264:Carboxylic Acids / Q000737:chemistry*; D002417:Cattle; D005456:Fluorescent Dyes / Q000737:chemistry; D006801:Humans; D053758:Nanoparticles / Q000737:chemistry*; D009838:Oligodeoxyribonucleotides / Q000737:chemistry*; D055672:Static Electricity; D013917:Thrombin / Q000032:analysis*; D013997:Time Factors
chemical_list: D052157:Aptamers, Nucleotide; D002264:Carboxylic Acids; D005456:Fluorescent Dyes; D009838:Oligodeoxyribonucleotides; D002244:Carbon; D013917:Thrombin