title: End point selection in acute decompensated heart failure clinical trials: economic end points.
abstract: The selection of economic end points in acute decompensated heart failure (ADHF) clinical trials requires prospectively planned evaluations that are developed in tandem with clinical end points. Integrating economic end points with concrete clinical outcomes postdischarge will provide meaningful data to evaluate a treatment's incremental value in the setting of ADHF.
authors.affiliation: Department of Medicine, Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC 27715, USA. shelby.reed@duke.edu
authors.forename: Shelby D
authors.initials: SD
authors.lastname: Reed
authors.forename: Zubin J
authors.initials: ZJ
authors.lastname: Eapen
authors.forename: Kevin A
authors.initials: KA
authors.lastname: Schulman
mesh_terms: D000208:Acute Disease; D002986:Clinical Trials as Topic / Q000191:economics*; D018450:Disease Progression; D017048:Health Care Costs; D006333:Heart Failure / Q000191:economics* / Q000628:therapy; D006801:Humans; D014481:United States