title: Daily muscle vibration amelioration of neural impairments of the soleus muscle during 2 weeks of immobilization.
abstract: V-wave, F wave and H-reflex responses of soleus were used to determine neural adaptations to 2-week immobilization and whether muscle vibration intervention during immobilization would attenuate the negative adaptations induced by immobilization. Thirty subjects were divided into the ankle immobilization group and the immobilization with muscle vibration group. Mechanical vibrations with constant low amplitude (0.3mm) were applied (12×4 min daily) with a constant frequency of 100Hz on the soleus muscle of the subjects in vibration group during the ankle immobilization period. Soleus maximal M-wave (Mmax) and H-reflex (Hmax) were evoked at rest. F-wave was recorded by supramaximal stimulation delivered at rest and V-wave during maximum voluntary contraction (MVC). The EMG during MVC was represented by its root-mean-square (RMS) value. Each subject was examined before and after 2 weeks of immobilization. Results showed that following 2 weeks of immobilization, Mmax, Hmax and F wave all did not change with immobilization in either group (P>0.05). After 2 weeks of immobilization, significant reductions in V/Mmax (of 30.78%) (P<0.01) and EMG RMS (24.82%) (P<0.001) were found in the immobilization group. However, no significant changes occurred in the immobilization with muscle vibration group. Such findings suggested that 2 weeks of immobilization resulted in neural impairments as evidenced by the reduction in EMG and V wave, and that such decrease was prevented by the intervention of muscle vibration during the immobilization period.
authors.affiliation: Department of Physiology and Pathophysiology, Medical School, Xi'an Jiaotong University, Xi'an, Shaanxi 710061, PR China.
authors.forename: Xuehong
authors.initials: X
authors.lastname: Zhao
authors.forename: Xiaoli
authors.initials: X
authors.lastname: Fan
authors.forename: Xin'ai
authors.initials: X
authors.lastname: Song
authors.forename: Lei
authors.initials: L
authors.lastname: Shi
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D007103:Immobilization / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D009119:Muscle Contraction; D018482:Muscle, Skeletal / Q000294:innervation / Q000503:physiopathology*; D009135:Muscular Diseases / Q000209:etiology / Q000503:physiopathology* / Q000517:prevention & control*; D012018:Reflex; D016896:Treatment Outcome; D014732:Vibration / Q000627:therapeutic use*; D055815:Young Adult