title: [The use of silymarin in patients with toxic and viral liver diseases].
abstract: Effective use of Silybum marianum medicines is still urgent in hepatology practice. Data about effectiveness and safety of silymarin in patients with acute and chronic toxic injuries including drug-induced ones and patients with acute and chronic viral hepatitis is reviewed in the article. An attempt of trials limitations and disadvantages systematization is made and methods of their solvation are discussed. A possibility of silymarin use as antiviral agent in patients with chronic hepatitis C is also reviewed and perspectives of this drug clinical use in future is discussed.
authors.forename: A V
authors.initials: AV
authors.lastname: Matveev
authors.forename: E I
authors.initials: EI
authors.lastname: Koniaeva
mesh_terms: D056486:Chemical and Drug Induced Liver Injury / Q000188:drug therapy* / Q000209:etiology; D002986:Clinical Trials as Topic; D006525:Hepatitis, Viral, Human / Q000188:drug therapy* / Q000821:virology; D006801:Humans; D020011:Protective Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D012838:Silymarin / Q000008:administration & dosage / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D020011:Protective Agents; D012838:Silymarin