title: Occurrence and risk factors of mild cognitive impairment in the older Chinese population: a 3-year follow-up study.
abstract: OBJECTIVE
  To investigate the occurrence and risk factors of mild cognitive impairment (MCI) and the conversion rates to dementia in Chinese people over 80 years of age.
  
  
  METHODS
  Two hundred and two participants (>80 years old) without dementia were assessed clinically using neuropsychological tests; they were re-assessed at 1, 2, and 3 years.
  
  
  RESULTS
  The results revealed that 30.2% of the study population was classified as having MCI at baseline. Multivariate linear regression analysis showed that coronary heart disease, hypertension, and stroke were risk factors of MCI. During the 3 years follow-up, the occurrence of MCI increased, and 21.8% of the participants with MCI progressed to dementia.
  
  
  CONCLUSIONS
  These results suggest that in the older elderly, prevention and early treatment of cardiovascular and cerebrovascular diseases may be effective in lowering the risk of MCI. MCI is a high risk factor for dementia.
authors.affiliation: Department of Geriatrics, West China Hospital of Sichuan University, Chengdu, China.
authors.forename: Shan
authors.initials: S
authors.lastname: Hai
authors.forename: Birong
authors.initials: B
authors.lastname: Dong
authors.forename: Yixin
authors.initials: Y
authors.lastname: Liu
authors.forename: Yupei
authors.initials: Y
authors.lastname: Zou
mesh_terms: D000369:Aged, 80 and over; D000428:Alcohol Drinking; D002681:China / Q000453:epidemiology; D060825:Cognitive Dysfunction / Q000453:epidemiology* / Q000209:etiology; D003327:Coronary Disease / Q000150:complications; D003704:Dementia / Q000453:epidemiology*; D018450:Disease Progression; D004522:Educational Status; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006973:Hypertension / Q000150:complications; D016015:Logistic Models; D008297:Male; D015995:Prevalence; D012307:Risk Factors; D020521:Stroke / Q000150:complications