title: Facial basal cell carcinoma: analysis of recurrence and follow-up strategies.
abstract: Rates of recurrence after incomplete surgical excision of basal cell carcinoma             (BCC) range from 4 to 16.6% of analyzed cases. The aim of the present study was             to identify the predictive factors associated with facial BBC recurrence following             excision and their influences, in order to establish a proper therapeutic strategy.             A monocentric retrospective study was performed reviewing all BCCs surgically             excised at the Institute of Plastic Surgery, University of Padua, with particular             focus on the involvement of surgical margins and recurrence. Seven hundred and             nineteen lesions in 605 patients were studied. Correlations between recurrence             probability and various characteristics of BCC were analyzed using a logistic             regression model. It was observed that incomplete excision, deep margin involvement,             the presence of sclerodermiform or metatypic basaloid squamous cells, as well             as pleomorphous histological variants and/or peritumoral inflammatory infiltrates,             were all related to an increase in the probability of recurrence. BCC excision             must be followed by individualized management with particular consideration for             the localization, the histological type and other known predisposing factors;             the treatment strategy and, in particular, the length of the surveillance period             and the frequency of patient assessment should be evaluated on the basis of the             recurrence probability outlined.
authors.affiliation: Unit of Plastic Surgery, Department of Statistical Sciences, University of Padua, Padua, Italy.
authors.forename: Leonardo
authors.initials: L
authors.lastname: Sartore
authors.forename: Luca
authors.initials: L
authors.lastname: Lancerotto
authors.forename: Michela
authors.initials: M
authors.lastname: Salmaso
authors.forename: Giorgio
authors.initials: G
authors.lastname: Giatsidis
authors.forename: Omar
authors.initials: O
authors.lastname: Paccagnella
authors.forename: Mauro
authors.initials: M
authors.lastname: Alaibac
authors.forename: Franco
authors.initials: F
authors.lastname: Bassetto
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002280:Basal Cell Carcinoma / Q000453:epidemiology* / Q000601:surgery; D018572:Disease-Free Survival; D005153:Facial Neoplasms / Q000453:epidemiology* / Q000601:surgery; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009364:Neoplasm Recurrence, Local / Q000453:epidemiology* / Q000601:surgery