title: Acute renal failure in the pediatric age group - single center prospective study of 180 cases.
abstract: Acute renal failure (ARF) is one of the common emergencies in pediatric practice. In the Indian subcontinent, its etiology, clinical features and outcome vary from other parts of the world. We decided to perform a prospective study of ARF in 180 pediatric patients admitted to our institute between August 2006 and March 2008. Our study included children, neonates 7.8%, <1 year 16.7%, 1-5 years 30.5% and >5 years comprised 52.8%. The male:female ratio was 2.3:1. Acute tubular necrosis remains the major cause of ARF; other intrinsic renal disease accounted for almost 30% of the patients. In all patients of ARF who required dialysis, peritoneal dialysis was offered as the first-line management. Six patients were offered hemodialysis. Mortality below one year age was higher compared with those who were more than one year of age (40% vs 11.3%). The overall mortality in the present study was 17.7%. ARF in pediatric nephrology is not uncommon. In our setup, peritoneal dialysis (PD) is an effective and safe modality of renal replacement therapy in most of the cases. Delayed referral, malnutrition, infections, age less than one year and multiorgan involvement were bad prognostic features.
authors.affiliation: Department of Nephrology and Clinical Transplantation, Dr. H. L. Trivedi Institute of Transplantation Sciences - Smt Gulabben Rasiklal Doshi and Smt Kamlaben Mafatlal Mehta Institute of Kidney Diseases and Research Centre, Civil Hospital Campus, Asarwa, Ahmedabad, Gujarat, India. drpankajrshah@yahoo.com
authors.forename: P R
authors.initials: PR
authors.lastname: Shah
authors.forename: J
authors.initials: J
authors.lastname: Falodia
authors.forename: V B
authors.initials: VB
authors.lastname: Kute
authors.forename: K V
authors.initials: KV
authors.lastname: Kanodia
authors.forename: A V
authors.initials: AV
authors.lastname: Vanikar
authors.forename: K R
authors.initials: KR
authors.lastname: Goplani
authors.forename: D N
authors.initials: DN
authors.lastname: Gera
authors.forename: H L
authors.initials: HL
authors.lastname: Trivedi
mesh_terms: D058186:Acute Kidney Injury / Q000453:epidemiology* / Q000209:etiology / Q000401:mortality / Q000628:therapy; D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007194:India / Q000453:epidemiology; D007223:Infant; D007673:Kidney Cortex Necrosis / Q000150:complications; D008297:Male; D010530:Peritoneal Dialysis; D011379:Prognosis; D011446:Prospective Studies