title: [Minimization of endogenous intoxication syndrome by individual choice of drugs for therapy of chronic hepatitis].
abstract: The results of clinical and laboratory examination of 107 children suffering from chronic hepatitis B or C were analysed. The biochemical criteria of the endogenous intoxication were investigated. Specific blood tests with antiviral drugs were conducted before the treatment and individual therapy schemes were assigned according to the tests' results. The early and sustained virological response rates during the individual antiviral treatment of the children with chronic hepatitis C proved to be 70.83 and 62.5% respectively.
authors.forename: D K
authors.initials: DK
authors.lastname: Vasil'eva
authors.forename: L G
authors.initials: LG
authors.lastname: Goriacheva
authors.forename: M Ia
authors.initials: MIa
authors.lastname: Kotiv
authors.forename: L A
authors.initials: LA
authors.lastname: Alekseeva
authors.forename: M G
authors.initials: MG
authors.lastname: Romantsov
authors.forename: T V
authors.initials: TV
authors.lastname: Bessonova
mesh_terms: D000166:Acridines / Q000191:economics / Q000627:therapeutic use*; D000293:Adolescent; D000998:Antiviral Agents / Q000191:economics / Q000627:therapeutic use*; D058345:Asymptomatic Infections / Q000628:therapy; D015415:Biomarkers / Q000032:analysis; D002648:Child; D002675:Child, Preschool; D003362:Cost-Benefit Analysis / Q000191:economics; D004359:Drug Therapy, Combination; D019694:Hepatitis B, Chronic / Q000175:diagnosis / Q000188:drug therapy / Q000191:economics; D019698:Hepatitis C, Chronic / Q000175:diagnosis / Q000188:drug therapy / Q000191:economics; D006801:Humans; D007369:Interferon Inducers / Q000191:economics / Q000627:therapeutic use*; D016898:Interferon-alpha / Q000191:economics / Q000627:therapeutic use*; D012254:Ribavirin / Q000191:economics / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D000166:Acridines; D000998:Antiviral Agents; D015415:Biomarkers; D007369:Interferon Inducers; D016898:Interferon-alpha; D012254:Ribavirin; C026430:10-carboxymethyl-9-acridanone