title: Proteins on the move: insights gained from fluorescent protein technologies.
abstract: Proteins are always on the move, and this may occur through diffusion or active transport. The realization that the regulation of signal transduction is highly dynamic in space and time has stimulated intense interest in the movement of proteins. Over the past decade, numerous new technologies using fluorescent proteins have been developed, allowing us to observe the spatiotemporal dynamics of proteins in living cells. These technologies have greatly advanced our understanding of protein dynamics, including protein movement and protein interactions.
authors.affiliation: Life Function and Dynamics, Exploratory Research for Advanced Technology, Japan Science and Technology Corporation, Saitama, Japan. matsushi@brain.riken.jp
authors.forename: Atsushi
authors.initials: A
authors.lastname: Miyawaki
mesh_terms: D000818:Animals; D001709:Biotechnology / Q000379:methods*; D049452:Green Fluorescent Proteins / Q000235:genetics / Q000378:metabolism; D006801:Humans; D008164:Luminescent Proteins / Q000235:genetics / Q000378:metabolism*; D011485:Protein Binding; D011506:Proteins; D015398:Signal Transduction / Q000235:genetics / Q000502:physiology
chemical_list: D008164:Luminescent Proteins; D011506:Proteins; D049452:Green Fluorescent Proteins