title: Stereotactic body radiation therapy for prostate cancer.
abstract: Stereotactic body radiation therapy (SBRT) is a promising treatment option for prostate cancer. Hypofractionation regimens, such as SBRT, may be more advantageous compared with conventional regimens because low α:β ratio of prostate cancer has high sensitivity to dose per fraction. In addition, a smaller and tighter margin with SBRT is expected to provide a low toxicity rate without reducing tumor control. The purpose of this article is to examine radiobiological, technical and clinical aspects of SBRT for prostate cancer.
authors.affiliation: Department of Radiation Oncology, The Methodist Hospital & Research Institute, Houston, TX 77030, USA.
authors.forename: Hiromichi
authors.initials: H
authors.lastname: Ishiyama
authors.forename: Bin S
authors.initials: BS
authors.lastname: Teh
authors.forename: Simon S
authors.initials: SS
authors.lastname: Lo
authors.forename: Thomas
authors.initials: T
authors.lastname: Mathews
authors.forename: Angel
authors.initials: A
authors.lastname: Blanco
authors.forename: Robert
authors.initials: R
authors.lastname: Amato
authors.forename: Rodney J
authors.initials: RJ
authors.lastname: Ellis
authors.forename: Nina A
authors.initials: NA
authors.lastname: Mayr
authors.forename: Arnold C
authors.initials: AC
authors.lastname: Paulino
authors.forename: Bo
authors.initials: B
authors.lastname: Xu
authors.forename: Brian E
authors.initials: BE
authors.lastname: Butler
mesh_terms: D000818:Animals; D019583:Dose Fractionation, Radiation; D006801:Humans; D008297:Male; D011471:Prostatic Neoplasms / Q000601:surgery*; D016634:Radiosurgery / Q000191:economics