title: Antibacterial potential of citral derivatives.
abstract: Nine conjugated acid derivatives from monoterpene citral have been synthesized using ester, amide condensations, Wittig, Knoevenagel, Baylis-Hillman reactions and their antimicrobial activities were evaluated through disc diffusion and serial dilution methods. Several derivatives displayed interesting antimicrobial activity. Particularly, the Baylis-Hillman adducts 8-10 were found to have more potent antibacterial and antifungal activities than standard drugs namely chloramphenicol and nystatin respectively.
authors.affiliation: Advanced Research Laboratory in Natural and Synthetic Chemistry, Department of Biotechnology, V. G. Vaze College, Mumbai University, Mithagar Road, Mulund (E), Mumbai 400 0081, India.
authors.forename: Soni A
authors.initials: SA
authors.lastname: Singh
authors.forename: Yogesh A
authors.initials: YA
authors.lastname: Potdar
authors.forename: Rasika S
authors.initials: RS
authors.lastname: Pawar
authors.forename: Sujata V
authors.initials: SV
authors.lastname: Bhat
mesh_terms: D000080462:Acyclic Monoterpenes; D015394:Molecular Structure; D039821:Monoterpenes / Q000737:chemistry* / Q000494:pharmacology*
chemical_list: D000080462:Acyclic Monoterpenes; D039821:Monoterpenes; C007076:citral