title: Palladium-catalyzed approach to stereodefined ten-membered cycles from 1,5-bisallenes.
abstract: A three-component Pd(0)-catalyzed reaction of 1,5-bisallenes with organic halides in the presence of primary amines was observed to afford stereodefined not readily available ten-membered cyclic compounds highly chemo- and regioselectively. A mechanism involving two π-allylic palladium intermediates was proposed to account for the observed regio- and stereoselectivity.
authors.affiliation: State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Lu, Shanghai 200032, PR China.
authors.forename: Jiajia
authors.initials: J
authors.lastname: Cheng
authors.forename: Xuefeng
authors.initials: X
authors.lastname: Jiang
authors.forename: Shengming
authors.initials: S
authors.lastname: Ma
mesh_terms: D000466:Alkadienes / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D008958:Models, Molecular; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000466:Alkadienes; C025947:propadiene; D010165:Palladium