title: Primary retroperitoneal mucinous cystadenocarcinoma with mural nodules: a case report and literature review.
abstract: A primary retroperitoneal mucinous cystadenocarcinoma (PRMC) is an extremely rare lesion. To date, only 49 cases have been reported. The presence of mural nodules in a PRMC may indicate a worse prognosis. We report the case of a 40-year-old Japanese woman with a PRMC with mural nodules. Microscopic examination revealed that the stromal cells of the nodules were spindle-shaped and varied in size. The nodules were immunoreactive for vimentin but negative for cytokeratin and EMA, and the nuclei of the stromal cells were pleomorphic and strongly Ki-67 immunoreactive. The nodules were diagnosed as true sarcoma. To the best of our knowledge, this is 11th published case report of a PRMC with mural nodules.
authors.affiliation: Department of Obstetrics and Gynecology, Graduate School of Medicine, Osaka University, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
authors.forename: Tomoko
authors.initials: T
authors.lastname: Kanayama
authors.forename: Kiyoshi
authors.initials: K
authors.lastname: Yoshino
authors.forename: Takayuki
authors.initials: T
authors.lastname: Enomoto
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Ohashi
authors.forename: Masami
authors.initials: M
authors.lastname: Fujita
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Ueda
authors.forename: Toshihiro
authors.initials: T
authors.lastname: Kimura
authors.forename: Eiji
authors.initials: E
authors.lastname: Kobayashi
authors.forename: Eiichi
authors.initials: E
authors.lastname: Morii
authors.forename: Tadashi
authors.initials: T
authors.lastname: Kimura
mesh_terms: D000328:Adult; D018282:Cystadenocarcinoma, Mucinous / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D007633:Keratins; D011379:Prognosis; D012186:Retroperitoneal Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D012509:Sarcoma / Q000473:pathology; D014746:Vimentin
chemical_list: D014746:Vimentin; D007633:Keratins