title: Green factory: plants as bioproduction platforms for recombinant proteins.
abstract: Molecular farming, long considered a promising strategy to produce valuable recombinant proteins not only for human and veterinary medicine, but also for agriculture and industry, now has some commercially available products. Various plant-based production platforms including whole-plants, aquatic plants, plant cell suspensions, and plant tissues (hairy roots) have been compared in terms of their advantages and limits. Effective recombinant strategies are summarized along with descriptions of scalable culture systems and examples of commercial progress and success.
authors.affiliation: Arkansas Biosciences Institute, Arkansas State University, Jonesboro, AR 72401, United States.
authors.forename: Jianfeng
authors.initials: J
authors.lastname: Xu
authors.forename: Maureen C
authors.initials: MC
authors.lastname: Dolan
authors.forename: Giuliana
authors.initials: G
authors.lastname: Medrano
authors.forename: Carole L
authors.initials: CL
authors.lastname: Cramer
authors.forename: Pamela J
authors.initials: PJ
authors.lastname: Weathers
mesh_terms: D019149:Bioreactors; D001709:Biotechnology / Q000191:economics / Q000379:methods*; D002478:Cells, Cultured; D003132:Commerce; D006801:Humans; D010944:Plants / Q000378:metabolism*; D011994:Recombinant Proteins / Q000096:biosynthesis* / Q000145:classification / Q000191:economics
chemical_list: D011994:Recombinant Proteins