title: Diarrhea-related hemolytic uremic syndrome: unmasking antifactor H antibodies.
abstract: The cases of hemolytic uremic syndrome (HUS) preceeded by diarrhea are commonly labeled as D+ HUS. However, with severe renal failure or with delayed recovery, such cases should be evaluated for rarer associations like Factor H (FH), I and CD 46 deficiency or mutations. We report such a presentation of a young boy who initially came with diarrhea and had features of HUS with delayed renal recovery. He later turned out to have anti-FH antibody-related HUS.
authors.affiliation: Department of Nephrology, All India Institute of Medical Sciences, New Delhi, India. parthankur@yahoo.com
authors.forename: Ankur
authors.initials: A
authors.lastname: Gupta
authors.forename: Ambar
authors.initials: A
authors.lastname: Khaira
authors.forename: Om P
authors.initials: OP
authors.lastname: Rathi
authors.forename: Sandeep
authors.initials: S
authors.lastname: Mahajan
authors.forename: Dipankar
authors.initials: D
authors.lastname: Bhowmik
authors.forename: Sanjay K
authors.initials: SK
authors.lastname: Agarwal
authors.forename: Suresh C
authors.initials: SC
authors.lastname: Tiwari
mesh_terms: D000293:Adolescent; D065766:Atypical Hemolytic Uremic Syndrome; D017242:Complement Factor H / Q000235:genetics / Q000276:immunology*; D003967:Diarrhea / Q000150:complications* / Q000276:immunology; D006463:Hemolytic-Uremic Syndrome / Q000150:complications* / Q000175:diagnosis / Q000276:immunology*; D006801:Humans; D008297:Male
chemical_list: D017242:Complement Factor H