title: Tumor microvasculature targeting with dendrimer-entrapped gold nanoparticles.
abstract: Monodisperse dendrimer-entrapped gold nanoparticles (diameter = 3.0 nm) were prepared using G5 poly(amidoamine) (PAMAM) dendrimer functionalized with fluorescein isothiocyanate (FI) and Arg-Gly-Asp (RGD) peptide as template; in vitro targeting efficacy to integrin receptor expressing cells was confirmed by flow cytometry, confocal microscopy, and ICP-MS.
authors.affiliation: Michigan Nanotechnology Institute for Medicine and Biological Sciences, University of Michigan, Ann Abor, MI 48109, USA.
authors.forename: Rameshwer
authors.initials: R
authors.lastname: Shukla
authors.forename: Elliott
authors.initials: E
authors.lastname: Hill
authors.forename: Xiangyang
authors.initials: X
authors.lastname: Shi
authors.forename: Jinkoo
authors.initials: J
authors.lastname: Kim
authors.forename: Maria C
authors.initials: MC
authors.lastname: Muniz
authors.forename: Kai
authors.initials: K
authors.lastname: Sun
authors.forename: James R
authors.initials: JR
authors.lastname: Baker