title: Primary gastric diffuse large B-cell lymphoma with orbital involvement: diagnostic usefulness of 18F-fluorodeoxyglucose positron emission tomography.
abstract: A 38-year-old man presented to our hospital with abdominal pain and melena. Gastrointestinal endoscopy revealed a large gastric ulcer, and the pathological diagnosis of diffuse large B-cell lymphoma (DLBCL) was made based on immunohistochemical findings. Left diplopia developed soon after commencement of chemotherapy. Despite normal findings from head MRI, orbital involvement in DLBCL was detected with 18F-fluorodeoxyglucose positron emission tomography (FDG-PET). The patient was treated with salvage chemotherapy with success. Treatment analysis using FDG-PET for patients with DLBCL, especially for those with clinical symptoms and negative findings on conventional modalities, may be useful for assessing disease status and adjusting treatments.
authors.affiliation: Department of Gastroenterology, Shinshu University School of Medicine, Japan. yiwaya@shinshu-u.ac.jp
authors.forename: Yugo
authors.initials: Y
authors.lastname: Iwaya
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Takenaka
authors.forename: Taiji
authors.initials: T
authors.lastname: Akamatsu
authors.forename: Yuki
authors.initials: Y
authors.lastname: Yamada
authors.forename: Shin
authors.initials: S
authors.lastname: Haba
authors.forename: Kensuke
authors.initials: K
authors.lastname: Matsuda
authors.forename: Hideyuki
authors.initials: H
authors.lastname: Nakazawa
authors.forename: Takashi
authors.initials: T
authors.lastname: Muraki
authors.forename: Yasunori
authors.initials: Y
authors.lastname: Kaneko
authors.forename: Toshiro
authors.initials: T
authors.lastname: Ito
authors.forename: Kenji
authors.initials: K
authors.lastname: Sano
authors.forename: Norikazu
authors.initials: N
authors.lastname: Arakura
authors.forename: Eiji
authors.initials: E
authors.lastname: Tanaka
authors.forename: Fumihiro
authors.initials: F
authors.lastname: Ishida
mesh_terms: D000328:Adult; D001706:Biopsy; D004358:Drug Therapy; D016099:Endoscopy, Gastrointestinal; D019788:Fluorodeoxyglucose F18; D006801:Humans; D016403:Lymphoma, Large B-Cell, Diffuse / Q000175:diagnosis* / Q000188:drug therapy; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D009915:Orbit / Q000000981:diagnostic imaging / Q000473:pathology; D009918:Orbital Neoplasms / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000556:secondary*; D049268:Positron-Emission Tomography; D016879:Salvage Therapy; D013274:Stomach Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology*; D016896:Treatment Outcome
chemical_list: D019788:Fluorodeoxyglucose F18