title: Early and long-term prognosis of patients with coronary artery disease treated with percutaneous coronary interventions in 2005. Experience of single large-volume PCI center.
abstract: OBJECTIVE
  The progress which has been made in interventional cardiology contributes to the gradual improvement of the results of CHD (coronary heart disease) therapy. The aim of the study was the assessment of early and long-term prognosis in all the patients with CHD treated invasively in one large-volume PCI center in 2005.
  
  
  METHODS
  1390 consecutive patients with CHD treated with PCI in 2005 were included in the analysis. Patients with ST-elevation myocardial infarction (STEMI) accounted for 50% of cases, patients with stable angina (SA) amounted to 25%, and patients with non-ST elevation acute coronary syndromes (NSTE-ACS) constituted 25%. Mean follow-up was 738 (±237) days.
  
  
  RESULTS
  The highest mortality during the hospitalization was noted within the STEMI group(SA vs. NSTE-ACS vs. STEMI; 0% vs. 0.3% vs. 4.1%, respectively; p<0.001). The highest mortality during a 2-year follow-up was also observed in the STEMI group (SA vs. NSTE-ACS vs. STEMI, 6.3% vs. 8.5% vs. 13.8%, respectively; p<0.001). Multiple regression model showed that independent risk factors for death during the follow-up were: age, glycaemia at admission, heart rate, blood pressure, ejection fraction, STEMI, ineffective PCI (R=0.3613; F(10.131)=19.672; p<0.0001 for the model).
  
  
  CONCLUSIONS
  The highest relative increase of mortality after the discharge of patients with CHD undergoing PCI referred to the patients with NSTE-ACS. However, in the real life PCI practice STEMI patients have the worst hospital and long-term prognosis. Well recognized risk factors for death in patients with CHD are still of great importance in negative prognosis of patients undergoing PCI.
authors.affiliation: Department of Invasive Cardiology, Medical University of Bialystok, Bialystok, Poland. marcinkozuch@poczta.onet.pl
authors.forename: M
authors.initials: M
authors.lastname: Kozuch
authors.forename: P
authors.initials: P
authors.lastname: Kralisz
authors.forename: J
authors.initials: J
authors.lastname: Korecki
authors.forename: M
authors.initials: M
authors.lastname: Rog-Makal
authors.forename: P
authors.initials: P
authors.lastname: Prokopczuk
authors.forename: H
authors.initials: H
authors.lastname: Bachorzewska-Gajewska
authors.forename: K
authors.initials: K
authors.lastname: Nowak
authors.forename: B
authors.initials: B
authors.lastname: Poniatowski
authors.forename: E
authors.initials: E
authors.lastname: Sitniewska
authors.forename: B
authors.initials: B
authors.lastname: Sobkowicz
authors.forename: W J
authors.initials: WJ
authors.lastname: Musial
authors.forename: M
authors.initials: M
authors.lastname: Jozwowicz
authors.forename: R
authors.initials: R
authors.lastname: Sabiniewicz
authors.forename: S
authors.initials: S
authors.lastname: Dobrzycki
mesh_terms: D000368:Aged; D015906:Angioplasty, Balloon, Coronary / Q000379:methods*; D002309:Cardiology / Q000379:methods*; D003324:Coronary Artery Disease / Q000175:diagnosis / Q000401:mortality / Q000628:therapy*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D015233:Models, Statistical; D009203:Myocardial Infarction / Q000175:diagnosis / Q000401:mortality / Q000628:therapy; D011379:Prognosis; D012044:Regression Analysis; D012307:Risk Factors; D016896:Treatment Outcome