title: Laboratory-confirmed case of yaws in a 10-year-old boy from the Republic of the Congo.
abstract: We report a case of yaws in a patient with puritic cutaneous eruption who was initially suspected of infection with monkeypox. The diagnosis was established by real-time PCR and sequencing of specific treponemal DNA sequences. This is the first report describing the use of DNA sequencing to identify Treponema pallidum subsp. pertenue-specific sequences in a patient with active yaws.
authors.affiliation: Laboratory Reference and Research Branch, Division of Sexually Transmitted Disease Prevention, NCHHSTP,, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA. apillay@cdc.gov
authors.forename: Allan
authors.initials: A
authors.lastname: Pillay
authors.forename: Cheng-Yen
authors.initials: CY
authors.lastname: Chen
authors.forename: Mary G
authors.initials: MG
authors.lastname: Reynolds
authors.forename: Jean V
authors.initials: JV
authors.lastname: Mombouli
authors.forename: Arnold C
authors.initials: AC
authors.lastname: Castro
authors.forename: Davy
authors.initials: D
authors.lastname: Louvouezo
authors.forename: Bret
authors.initials: B
authors.lastname: Steiner
authors.forename: Ronald C
authors.initials: RC
authors.lastname: Ballard
mesh_terms: D002648:Child; D003223:Congo; D004269:DNA, Bacterial / Q000737:chemistry / Q000235:genetics; D006801:Humans; D008297:Male; D008969:Molecular Sequence Data; D060888:Real-Time Polymerase Chain Reaction; D017422:Sequence Analysis, DNA; D017192:Skin Diseases, Bacterial / Q000382:microbiology / Q000473:pathology; D014210:Treponema pallidum / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification*; D015001:Yaws / Q000175:diagnosis* / Q000382:microbiology
chemical_list: D004269:DNA, Bacterial