title: Convenient synthesis of 3-vinyl and 3-styryl coumarins.
abstract: A variety of 2-hydroxy aldehydes on reaction with 3-butenoic acid afford in a one-pot reaction the corresponding 3-vinylcoumarins. As expected, extension of the delocalized π-electron system accomplished by Heck coupling reactions with aryl halides results in an increased fluorescence of the compounds whose applicability is yet to be established.
authors.affiliation: REQUIMTE, Departamento de Química, Faculdade de Ciências e Tecnologia, FCT, Universidade Nova de Lisboa, Portugal.
authors.forename: Joana
authors.initials: J
authors.lastname: Gordo
authors.forename: João
authors.initials: J
authors.lastname: Avó
authors.forename: A Jorge
authors.initials: AJ
authors.lastname: Parola
authors.forename: João C
authors.initials: JC
authors.lastname: Lima
authors.forename: António
authors.initials: A
authors.lastname: Pereira
authors.forename: Paula S
authors.initials: PS
authors.lastname: Branco
mesh_terms: D003374:Coumarins / Q000138:chemical synthesis*; D005456:Fluorescent Dyes / Q000138:chemical synthesis*; D015394:Molecular Structure; D013343:Styrenes / Q000737:chemistry*; D014753:Vinyl Compounds / Q000138:chemical synthesis*
chemical_list: D003374:Coumarins; D005456:Fluorescent Dyes; D013343:Styrenes; D014753:Vinyl Compounds