title: Using the same organocatalyst for asymmetric synthesis of both enantiomers of glutamic acid-derived Ni(II) complexes via 1,4-additions of achiral glycine and dehydroalanine Schiff base Ni(II) complexes.
abstract: (S)- and (R)-BIMBOL were efficient PT catalysts of asymmetric Michael addition of prochiral Ni-PBP-Gly (1) to acrylic esters and malonic esters to Ni-PBP-Δ-Ala (2) correspondingly. The salient feature of the catalysis is opposite configurations of Glu prepared via the two paths with BIMBOL of the same configuration and a perspective novel catalytic procedure for the synthesis of Gla derivatives.
authors.affiliation: Institute of Russian Academy of Sciences, A.N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, Vavilov str. 28, 119991, Moscow, Russia. yubel@ineos.ac.ru
authors.forename: Yuri N
authors.initials: YN
authors.lastname: Belokon
authors.forename: Zalina T
authors.initials: ZT
authors.lastname: Gugkaeva
authors.forename: Karine V
authors.initials: KV
authors.lastname: Hakobyan
authors.forename: Victor I
authors.initials: VI
authors.lastname: Maleev
authors.forename: Margarita A
authors.initials: MA
authors.lastname: Moskalenko
authors.forename: Victor N
authors.initials: VN
authors.lastname: Khrustalev
authors.forename: Ashot S
authors.initials: AS
authors.lastname: Saghyan
authors.forename: Alan T
authors.initials: AT
authors.lastname: Tsaloev
authors.forename: Kiryl K
authors.initials: KK
authors.lastname: Babievsky
mesh_terms: D015055:1-Carboxyglutamic Acid / Q000737:chemistry; D000409:Alanine / Q000031:analogs & derivatives / Q000737:chemistry; D002384:Catalysis; D018698:Glutamic Acid / Q000737:chemistry*; D005998:Glycine / Q000737:chemistry; D009284:Naphthols / Q000737:chemistry* / Q000378:metabolism; D009532:Nickel / Q000737:chemistry; D012545:Schiff Bases / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D009284:Naphthols; D012545:Schiff Bases; D018698:Glutamic Acid; D015055:1-Carboxyglutamic Acid; D009532:Nickel; C015102:dehydroalanine; D000409:Alanine; D005998:Glycine