title: Macular microcirculation blood flow after pars plana vitrectomy with silicone oil tamponade.
abstract: OBJECTIVE
  To assess the macular microcirculation blood flow with Doppler laser scanning (HRF-Heidelberg Retinal Flowmeter), in patients with complicated rhegmatogenous retinal detachment (RRD), after pars plana vitrectomy (PPV), with silicone oil tamponade.
  
  
  METHODS
  Eleven patients (6 males and 5 females), aged 38-64 years, mean age: 52.4 years, with unilateral macula-on complicated RRD were included in a study. In all cases conventional (20-gauge) pars plana vitectomy with silicone oil tamponade was performed. Control group consists of the fellow eyes.
  
  
  RESULTS
  In the early postoperative period (1-3 days after surgery), in all operated eyes the mean values of macular microcirculation blood flow were significantly reduced in the comparison with those of the control eyes (p = 0.01). The reduction of mean values of macular microcirculation blood flow was still observed in all silicone-oil-filled eyes one month after surgery as compared to the contralateral eyes (p = 0.01). There was no correlation between the values of macular microcirculation blood flow and the duration of RRD, baseline BCVA, refractive error, number of retinal tears, and the patient age.
  
  
  CONCLUSIONS
  The preliminary results of this study suggest that PPV with silicone oil tamponade influences over the retinal blood flow. We have observed that silicone oil may have a negative long-term effect on the retinal microcirculation as it was noted one month after surgery.
authors.affiliation: Clinic of Ophthalmology and Ocular Oncology, Department of Ophthalmology, Jagiellonian University, Medical College, Krakow, Poland. akubicka@onet.pl
authors.forename: Agnieszka
authors.initials: A
authors.lastname: Kubicka-Trzaska
authors.forename: Joanna
authors.initials: J
authors.lastname: Kobylarz
authors.forename: Bozena
authors.initials: B
authors.lastname: Romanowska-Dixon
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D017078:Laser-Doppler Flowmetry; D008266:Macula Lutea / Q000098:blood supply*; D008297:Male; D008833:Microcirculation; D008875:Middle Aged; D012039:Regional Blood Flow; D012163:Retinal Detachment / Q000503:physiopathology / Q000601:surgery*; D012827:Silicone Oils / Q000627:therapeutic use*; D041623:Tomography, Optical Coherence; D014821:Vitrectomy
chemical_list: D012827:Silicone Oils