title: Tailoring the specificity and reactivity of a mechanism-based inactivator of glucocerebrosidase for potential therapeutic applications.
authors.affiliation: Department of Chemistry, University of British Columbia, Vancouver, B.C. V6T 1Z1, Canada.
authors.forename: Brian P
authors.initials: BP
authors.lastname: Rempel
authors.forename: Michael B
authors.initials: MB
authors.lastname: Tropak
authors.forename: Don J
authors.initials: DJ
authors.lastname: Mahuran
authors.forename: Stephen G
authors.initials: SG
authors.lastname: Withers
mesh_terms: D002478:Cells, Cultured; D004791:Enzyme Inhibitors / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D005347:Fibroblasts / Q000187:drug effects / Q000201:enzymology; D005461:Fluorine / Q000737:chemistry; D005776:Gaucher Disease / Q000188:drug therapy*; D005962:Glucosylceramidase / Q000037:antagonists & inhibitors*; D006801:Humans
chemical_list: D004791:Enzyme Inhibitors; D005461:Fluorine; D005962:Glucosylceramidase