title: [Effect of vault irritation on the bulbar respiratory neurons during hypoxia].
abstract: Influence of the vault on the impulse activity of respiration center neurons in medulla oblongata and respiration was studied in the norm and during hypoxia. Hypoxia stages served as a test model for ensuing vault effect summation. In normoxia, electrical irritation of the vault had largely an activating effect. Moderate pO2 reduction with rising to the altitudes of 4000-5000 m activated pulsation of the respiratory neurons; influence of vault irritation was less evident than in normoxia even though it prevailed over inhibition. The respiratory neurons activity declined conspicuously at the peak altitude of 7500-8000 m and critical hypoxia; it was then that the facilitatory effect of vault irritation was especially strong. On "descent" to normal atmospheric pressure the spontaneous rhythmic activity of neurons and reaction to irritation returned gradually to baseline values.
authors.forename: N Iu
authors.initials: NIu
authors.lastname: Adamian
authors.forename: R S
authors.initials: RS
authors.lastname: Arutiunian
authors.forename: M A
authors.initials: MA
authors.lastname: Karapetian
mesh_terms: D000200:Action Potentials / Q000502:physiology*; D000222:Adaptation, Physiological; D000531:Altitude; D000818:Animals; D001274:Atmospheric Pressure; D002404:Catheterization; D002452:Cell Count; D004558:Electric Stimulation; D000860:Hypoxia; D008032:Limbic System / Q000502:physiology*; D008839:Microelectrodes; D009415:Nerve Net / Q000502:physiology; D009474:Neurons / Q000502:physiology; D051381:Rats; D012119:Respiration; D012125:Respiratory Center / Q000502:physiology*; D012143:Respiratory Physiological Phenomena