title: Mechanism of dioxindolylalanine formation by singlet molecular oxygen-mediated oxidation of tryptophan residues.
abstract: The singlet molecular oxygen-oxidation of tryptophan generates diastereoisomeric dioxindolylalanine (diOia) along with hydroperoxides, alcohols and carbonyl compounds. Mechanistic investigations based on isotopic labeling and MS/MS analyses support diOia formation through a dioxetane intermediate.
authors.affiliation: Instituto de Química, Universidade de São Paulo, SP, Brazil. ronsein@iq.usp.br
authors.forename: Graziella Eliza
authors.initials: GE
authors.lastname: Ronsein
authors.forename: Mauricio Cesar Bof
authors.initials: MC
authors.lastname: de Oliveira
authors.forename: Marisa Helena Gennari
authors.initials: MH
authors.lastname: de Medeiros
authors.forename: Paolo
authors.initials: P
authors.lastname: Di Mascio