title: Injectability and mechanical properties of magnesium phosphate cements.
abstract: Up to now magnesium phosphate cements are mainly being utilized in wastewater treatment due to their adsorptive properties. Recently they also have been shown to have a high potential as degradable biocements for application as replacement materials for bone defects. In comparison to degradable calcium phosphate cements they have the advantage of setting at neutral pH, which is favorable in biological environment. In this study two parameters of the cement composition, namely powder-to-liquid ratio (PLR) and citrate content, were varied in order to optimize the injectability properties of the cement paste and the mechanical properties of the reaction product. These properties were determined by means of testing setting time and temperature, paste viscosity, and injectability as well as phase composition and compressive strength of the set cements. Best results were obtained, when the cements were prepared with a PLR of 2.5 and a binder liquid consisting of an aqueous solution of 3 mol/l diammonium hydrogen phosphate and 0.5 mol/l diammonium citrate.
authors.affiliation: Department of Functional Materials in Medicine and Dentistry, School of Dentistry, University of Würzburg, Würzburg, Germany. claus.moseke@fmz.uni-wuerzburg.de
authors.forename: Claus
authors.initials: C
authors.lastname: Moseke
authors.forename: Vasileios
authors.initials: V
authors.lastname: Saratsis
authors.forename: Uwe
authors.initials: U
authors.lastname: Gbureck
mesh_terms: D000327:Adsorption; D001843:Bone Cements / Q000737:chemistry*; D018786:Bone Substitutes / Q000737:chemistry*; D002130:Calcium Phosphates / Q000737:chemistry; D019245:Compressive Strength; D006863:Hydrogen-Ion Concentration; D017616:Magnesium Compounds / Q000737:chemistry*; D008422:Materials Testing; D008855:Microscopy, Electron, Scanning; D010710:Phosphates / Q000737:chemistry*; D011208:Powders; D013314:Stress, Mechanical; D013696:Temperature; D014783:Viscosity; D014961:X-Ray Diffraction
chemical_list: D001843:Bone Cements; D018786:Bone Substitutes; D002130:Calcium Phosphates; D017616:Magnesium Compounds; D010710:Phosphates; D011208:Powders; C024788:ammonium phosphate; C030781:magnesium phosphate; C020243:calcium phosphate