title: DNA cytometry testing for cervical cancer screening: approaches and reporting standards for new technologies.
abstract: Evaluation of new technologies requires rigorous methods to provide unbiased estimates of the performance and so inform future clinical practice. We review evidence on DNA cytometry reported earlier in this journal and point to the standards for reporting of diagnostic accuracy as a metric against which this article can be evaluated. The cross-sectional nature of the data and incomplete reporting limit the clinical utility of the study. With application of improved reporting standards for diagnostic tests and improved design and evaluation of new technologies for screening, we may better inform practices to improve clinical outcomes and population health.
authors.affiliation: Division of Public Health Sciences, Department of Surgery, Washington University School of Medicine, St. Louis, MO 63110, USA. colditzg@wustl.edu
authors.forename: Graham A
authors.initials: GA
authors.lastname: Colditz
authors.forename: John
authors.initials: J
authors.lastname: Crowley
mesh_terms: D005260:Female; D006801:Humans; D019044:Image Cytometry; D011003:Ploidies; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis* / Q000235:genetics*