title: Comparison of CLSI broth macrodilution and microdilution methods for echinocandin susceptibility testing of 5 Candida species.
abstract: In order to compare the Clinical and Laboratory Standards Institute (CLSI) broth macrodilution and microdilution methods of susceptibility testing for echinocandins and yeast, 55 strains of Candida representing 5 species were tested using the CLSI-recommended broth macro- and microdilution methods. Small (1-3 log(2)) but potentially important method-, species-, and drug-dependent differences in MICs were observed.
authors.affiliation: Stratton VA Medical Center, Albany, NY 12208, USA.
authors.forename: Lawrence H
authors.initials: LH
authors.lastname: Bopp
authors.forename: Aldona L
authors.initials: AL
authors.lastname: Baltch
authors.forename: William J
authors.initials: WJ
authors.lastname: Ritz
authors.forename: Raymond P
authors.initials: RP
authors.lastname: Smith
mesh_terms: D000935:Antifungal Agents / Q000494:pharmacology*; D002175:Candida / Q000187:drug effects* / Q000302:isolation & purification; D054714:Echinocandins / Q000494:pharmacology*; D006801:Humans; D008826:Microbial Sensitivity Tests / Q000379:methods*; D015203:Reproducibility of Results
chemical_list: D000935:Antifungal Agents; D054714:Echinocandins