title: The Clinical Value of Performing an MRI before Prostate Biopsy.
abstract: OBJECTIVE
  Prostate cancer foci have a characteristic feature in magnetic resonance imaging (MRI). We aimed to assess the clinical value of MRI before prostate biopsy in prostate cancer detection.
  
  
  METHODS
  From March 2009 to June 2010, 154 patients were enrolled in this study. A total of 51 patients with a clinical suspicion of prostate cancer underwent prostate MRI by a 3T scanner before transrectal ultrasound (TRUS)-guided biopsies. A total of 103 patients with a clinical suspicion of prostate cancer underwent prostate MRI after biopsies. The sensitivity, specificity, and positive predictive value (PPV) were evaluated. In addition, tumor location of pathologic findings and ADC mapping on MRI were matched and compared.
  
  
  RESULTS
  The sensitivity of MRI before and after biopsy was 84.8% and 92.4%, respectively. The PPV of MRI before and after biopsy was 75.7% and 92.4%, respectively. The MRI location match percentage before and after biopsy was 89.3% and 94.1%, respectively.
  
  
  CONCLUSIONS
  Compared with other previous reports, our results show that the prostate cancer detection sensitivity of MRI is on the rise. Furthermore, MRI before prostate biopsy can provide more information by which to identify prostate cancer during prostate biopsy and thus reduce the false-negative rate.
authors.affiliation: Department of Urology, The Catholic University of Korea, College of Medicine, Seoul, Korea.
authors.forename: Myung Sun
authors.initials: MS
authors.lastname: Choi
authors.forename: Yong Sun
authors.initials: YS
authors.lastname: Choi
authors.forename: Byung Il
authors.initials: BI
authors.lastname: Yoon
authors.forename: Su Jin
authors.initials: SJ
authors.lastname: Kim
authors.forename: Hyuk Jin
authors.initials: HJ
authors.lastname: Cho
authors.forename: Sung Hoo
authors.initials: SH
authors.lastname: Hong
authors.forename: Ji Youl
authors.initials: JY
authors.lastname: Lee
authors.forename: Tae-Kon
authors.initials: TK
authors.lastname: Hwang
authors.forename: Sae Woong
authors.initials: SW
authors.lastname: Kim