title: The use of ticagrelor in a patient at increased risk of stent thrombosis resistant to multiple thienopyridines.
abstract: Ticagrelor has been shown to be superior to clopidogrel in patients presenting with acute myocardial infarction who undergo early invasive treatment. We discuss a hitherto unreported use of ticagrelor in the management of a patient resistant to multiple thienopyridines at high risk of stent thrombosis.
authors.affiliation: Manchester Heart Centre, Manchester Royal Infirmary, Manchester, UK.
authors.forename: Kenneth P
authors.initials: KP
authors.lastname: Morgan
authors.forename: Ranjit S
authors.initials: RS
authors.lastname: More
authors.forename: Anoop
authors.initials: A
authors.lastname: Chauhan
mesh_terms: D000241:Adenosine / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D000369:Aged, 80 and over; D006328:Cardiac Catheterization; D000077144:Clopidogrel; D054855:Drug-Eluting Stents; D006801:Humans; D008297:Male; D009203:Myocardial Infarction / Q000628:therapy; D058921:Purinergic P2Y Receptor Antagonists / Q000008:administration & dosage / Q000627:therapeutic use*; D058924:Thienopyridines / Q000627:therapeutic use; D013927:Thrombosis / Q000517:prevention & control*; D000077486:Ticagrelor; D013988:Ticlopidine / Q000031:analogs & derivatives / Q000627:therapeutic use; D016896:Treatment Outcome
chemical_list: D058921:Purinergic P2Y Receptor Antagonists; D058924:Thienopyridines; D000077144:Clopidogrel; D000077486:Ticagrelor; D000241:Adenosine; D013988:Ticlopidine