title: Adiponectin and metabolic syndrome in a Tunisian population.
abstract: The aim of this study was to investigate the relationship between the adiponectin levels and various characteristics of the metabolic syndrome (MS) in a sample of the Tunisian population. Three hundred and fifty-four individuals were included in this study. Body mass index, blood pressure, HDL-cholesterol, triglycerides, glucose, insulin, and adiponectin concentrations were measured. Insulin resistance was assessed by homeostasis model assessment of insulin resistance (HOMA-IR). MS was identified with the NCEP-ATP III criteria. Subjects with MS showed significantly lower adiponectin levels compared to those without MS. For both genders, the prevalence and the number of MS components increased significantly as the adiponectin concentrations decreased. Subjects with the lowest adiponectin quartile had an increased risk of MS adjusted for age, gender, and HOMA-IR. Our findings suggest that hypoadiponectinemia is strongly associated with the risk of MS independent of insulin resistance.
authors.affiliation: Research Laboratory LR99ES11, Biochemistry Department, Rabta University Hospital, Jabbari, Tunis 1007, Tunisia. Samir.BenAli@fst.rnu.tn
authors.forename: Samir
authors.initials: S
authors.lastname: Ben Ali
authors.forename: Riadh
authors.initials: R
authors.lastname: Jemaa
authors.forename: Bouchra
authors.initials: B
authors.lastname: Ftouhi
authors.forename: Amani
authors.initials: A
authors.lastname: Kallel
authors.forename: Moncef
authors.initials: M
authors.lastname: Feki
authors.forename: Hedia
authors.initials: H
authors.lastname: Slimene
authors.forename: Naziha
authors.initials: N
authors.lastname: Kaabachi
mesh_terms: D052242:Adiponectin / Q000097:blood*; D000328:Adult; D000368:Aged; D001827:Body Height; D015992:Body Mass Index; D001835:Body Weight; D005260:Female; D006801:Humans; D007333:Insulin Resistance; D008297:Male; D024821:Metabolic Syndrome / Q000097:blood* / Q000175:diagnosis; D008875:Middle Aged; D014416:Tunisia; D055815:Young Adult
chemical_list: D052242:Adiponectin