title: Outcome of eyes developing retinal detachment during the Early Treatment for Retinopathy of Prematurity study.
abstract: OBJECTIVE
  To describe the structural and visual outcomes at age 6 years of retinal detachment (RD) from retinopathy of prematurity (ROP) in the Early Treatment for Retinopathy of Prematurity (ETROP) study.
  
  
  METHODS
  Prospective multicenter nonrandomized series of infants with high-risk prethreshold ROP who developed an RD by 6 months corrected age treated with observation or vitreoretinal surgery.
  
  
  RESULTS
  Of 401 patients, 63 (89 eyes) experienced RD. Follow-up at age 6 years was available for 70 eyes (79%) of 49 surviving patients. The RDs were stage 4A in 28 eyes (40%), stage 4B in 14 (20%), stage 5 in 13 (19%), and not classified in 15 (21%). The macula was attached in 17 of 50 eyes (34%) after vitrectomy with or without scleral buckle, in 6 of 9 (67%) after scleral buckle only, and in 2 of 11 eyes (18%) observed. An attached macula at age 6 years after vitreoretinal surgery was present in 5 of 16 eyes (31%) with stage 4A, 6 of 10 (60%) with stage 4B, and 0 of 10 with stage 5. Favorable visual acuity (>20/200) was found in 6 of 70 eyes (9%); 5 had stage 4A, and 1 was not classified.
  
  
  CONCLUSIONS
  Macular attachment was achieved in approximately one-third of eyes with RD and favorable visual acuity in some eyes with stage 4A.
authors.affiliation: Wilmer Eye Institute and Department of Pediatrics, The Johns Hopkins University, Baltimore, MD 21287-9028, USA. mrepka@jhmi.edu
authors.forename: Michael X
authors.initials: MX
authors.lastname: Repka
authors.forename: Betty
authors.initials: B
authors.lastname: Tung
authors.forename: William V
authors.initials: WV
authors.lastname: Good
authors.forename: Antonio
authors.initials: A
authors.lastname: Capone
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Shapiro
mesh_terms: D002648:Child; D002675:Child, Preschool; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D019102:Infant, Very Low Birth Weight; D019370:Observation; D011446:Prospective Studies; D012163:Retinal Detachment / Q000209:etiology / Q000503:physiopathology* / Q000601:surgery; D012178:Retinopathy of Prematurity / Q000150:complications / Q000503:physiopathology* / Q000601:surgery; D012591:Scleral Buckling; D016896:Treatment Outcome; D014792:Visual Acuity / Q000502:physiology*; D014821:Vitrectomy