title: Redirecting traffic in the nucleus.
abstract: Nuclear spatial organization of genes has emerged as an important determinant of their transcriptional activity. In this issue, Wang et al. (2011) show that the Msx1 homeoprotein induces a dramatic redistribution of Ezh2 and H3K27me3 to the nuclear periphery of muscle progenitor cells to repress transcription of developmentally regulated genes.
authors.affiliation: Sprott Center for Stem Cell Research, Regenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, ON K1H 8L6, Canada.
authors.forename: Kulwant
authors.initials: K
authors.lastname: Singh
authors.forename: F Jeffrey
authors.initials: FJ
authors.lastname: Dilworth