title: Divergent synthetic routes for ring expansion or cyclization from 1,4-allylic diol derivatives via gold(I) catalysis or zinc(II) mediation.
abstract: A new efficient method was developed to transform cyclic alkanols into one-carbon higher homologated ketones using various esters as the leaving groups through gold-catalyzed allylic cation-promoted pinacol-type rearrangement. This reaction, coupled with oxy-Cope rearrangement, provided a new strategy to synthesize five-carbon homologated ring ketones. In addition, using ZnBr(2), 2,5-dihydrofuran products were obtained in moderate to good yields via an intramolecular cyclization process.
authors.affiliation: Department of Chemistry, Renmin University of China, Beijing 100872, China.
authors.forename: Li-Li
authors.initials: LL
authors.lastname: Zhu
authors.forename: Xiao-Xiao
authors.initials: XX
authors.lastname: Li
authors.forename: Wen
authors.initials: W
authors.lastname: Zhou
authors.forename: Xin
authors.initials: X
authors.lastname: Li
authors.forename: Zili
authors.initials: Z
authors.lastname: Chen