title: Diagnostic and prognostic value of procalcitonin and phosphorus in acute mesenteric ischemia.
abstract: BACKGROUND
  In this study, using an animal model of acute mesenteric ischemia (AMI), we investigated the possible use of procalcitonin and phosphorus in the early diagnosis of AMI.
  
  
  METHODS
  In this study, 21 New Zealand rabbits were used. Subjects were allocated into three groups as Control, Sham and Ischemia. No intervention was performed in the subjects in the Control group. In the subjects in the Sham and Ischemia groups, laparotomy was performed with midline incision. In the Ischemia group, the superior mesenteric artery was found and tied after laparotomy. Blood was drawn from the animals in all groups at 0, 1, 3 and 6 hours, and procalcitonin and phosphorus levels were studied in these samples.
  
  
  RESULTS
  In the Ischemia group, the increase in the levels of serum phosphorus and procalcitonin was found to be statistically significant compared to the Control and Sham groups (p<0.05). The levels of phosphorus and procalcitonin were detected to increase from the 1st hour after ischemia onset, and the increase continued for the following 6 hours (p<0.05).
  
  
  CONCLUSIONS
  Phosphorus and procalcitonin may be important parameters for use in the early diagnosis and prognosis of AMI.
authors.affiliation: Department of Emergency Medicine, Selçuk University Meram Faculty of Medicine, Konya, Turkey. dr_kezi@hotmail.com
authors.forename: Keziban
authors.initials: K
authors.lastname: Karabulut
authors.forename: Mehmet
authors.initials: M
authors.lastname: Gül
authors.forename: Zerrin Defne
authors.initials: ZD
authors.lastname: Dündar
authors.forename: Başar
authors.initials: B
authors.lastname: Cander
authors.forename: Sevil
authors.initials: S
authors.lastname: Kurban
authors.forename: Hatice
authors.initials: H
authors.lastname: Toy
mesh_terms: D000208:Acute Disease; D000818:Animals; D002116:Calcitonin / Q000097:blood*; D004195:Disease Models, Animal; D006023:Glycoproteins / Q000097:blood*; D007511:Ischemia / Q000097:blood / Q000175:diagnosis; D008638:Mesenteric Arteries; D008641:Mesenteric Vascular Occlusion / Q000097:blood / Q000175:diagnosis*; D010758:Phosphorus / Q000097:blood*; D011237:Predictive Value of Tests; D011379:Prognosis; D011498:Protein Precursors / Q000097:blood*; D011817:Rabbits
chemical_list: D006023:Glycoproteins; D011498:Protein Precursors; D010758:Phosphorus; D002116:Calcitonin