title: [The role of subclinical inflammation in the formation of early signs of cardiac lesions in hypertensive disease].
abstract: Compromised diastolic relaxation of the left ventricle occurs in hypertensive disease with and without its hypertrophy. Classic ventricular hypertension takes some time to develop during which manifestations of myocardial diastolic dysfunction remain the sole criterion (marker) of the lesion. Patients with uncomplicated arterial hypertension display interrelated changes in inflammation, endothelial function, and disorders at the level of different organs. These relationships are believed to be underlain by common neurohumoral mechanisms.
authors.forename: S A
authors.initials: SA
authors.lastname: Smakotina
authors.forename: T N
authors.initials: TN
authors.lastname: Zvereva
authors.forename: E D
authors.initials: ED
authors.lastname: Bazdyrev
authors.forename: O L
authors.initials: OL
authors.lastname: Barbarash
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000097:blood; D004727:Endothelium / Q000473:pathology; D005260:Female; D006801:Humans; D006973:Hypertension / Q000097:blood / Q000150:complications* / Q000473:pathology; D017379:Hypertrophy, Left Ventricular / Q000209:etiology* / Q000473:pathology / Q000503:physiopathology; D007249:Inflammation / Q000097:blood / Q000209:etiology* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009200:Myocardial Contraction
chemical_list: D015415:Biomarkers