title: Pressure modes of invasive mechanical ventilation.
abstract: Pressure modes of invasive mechanical ventilation generate a tidal breath by delivering pressure over time. Pressure control ventilation (PC) is the prototypical pressure mode and is patient- or time-triggered, pressure-limited, and time-cycled. Other pressure modes include pressure support ventilation (PSV), pressure-regulated volume control (PRVC, also known as volume control plus [VC+]), airway pressure release ventilation (APRV), and biphasic ventilation (also known as BiLevel). Despite their complexity, modern ventilators respond to patient effort and respiratory system mechanics in a fairly predictable fashion. No single mode has consistently demonstrated superiority in clinical trials; however, empiric management with a pressure mode may achieve the goals of patient-ventilator synchrony, effective respiratory system support, adequate gas exchange, and limited ventilator-induced lung injury.
authors.affiliation: Department of Medicine, and Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA. bsinger007@md.northwestern.edu
authors.forename: Benjamin D
authors.initials: BD
authors.lastname: Singer
authors.forename: Thomas C
authors.initials: TC
authors.lastname: Corbridge
mesh_terms: D002986:Clinical Trials as Topic; D045422:Continuous Positive Airway Pressure / Q000379:methods; D006801:Humans; D011175:Positive-Pressure Respiration / Q000379:methods; D011659:Pulmonary Gas Exchange; D012121:Respiration, Artificial / Q000379:methods*; D012128:Respiratory Distress Syndrome / Q000628:therapy; D015656:Respiratory Mechanics; D055397:Ventilator-Induced Lung Injury / Q000517:prevention & control