title: Haemophilus influenza endophthalmitis after pterygium surgery.
abstract: OBJECTIVE
  To describe a case of Haemophilus influenza endophthalmitis after pterygium surgery.
  
  
  METHODS
  Retrospective case report.
  
  
  RESULTS
  A 50-year-old Hispanic male underwent a pterygium excision with amniotic membrane graft (AMG) and 0.02% MMC. He presented 3.5 months later with severe pain, yellow-white discharge, and decreased visual acuity for several days, and conjunctival injection for 3 months. Repair of perforation with a corneal graft was performed. Intravitreal antibiotics were administered. Many β-lactamase negative H. influenza organisms were cultured from the vitreous aspirate. The vitritis significantly improved and hypopyon resolved over the next week. The patient underwent surgery for a combined tractional and rhegmatogenous RD 9 days later. The endophthalmitis resolved; however, he developed proliferative vitreoretinopathy (PVR) with redetached retina 21 days after the initial RD repair. He underwent subsequent surgery. Six months later, AMG was performed for recurrent corneal erosion with a large epithelial defect. At last follow-up, the vision remains at hand motions, the retina is flat, there is mild corneal decompensation, the eye is soft to palpation, and there are signs of early phthisis.
  
  
  CONCLUSIONS
  A prospective study to identify the optimal concentration and period of application for MMC, as well as patient characteristics resulting in the highest clinical benefit-to-risk ratio may be warranted.
authors.affiliation: Institute of Ophthalmology and Visual Science, University of Medicine and Dentistry of New Jersey, Newark, NJ 07101-1709, USA.
authors.forename: Anton M
authors.initials: AM
authors.lastname: Kolomeyer
authors.forename: Neelakshi
authors.initials: N
authors.lastname: Bhagat
authors.forename: David S
authors.initials: DS
authors.lastname: Chu
mesh_terms: D009877:Endophthalmitis / Q000382:microbiology*; D015818:Eye Infections, Bacterial / Q000382:microbiology*; D006192:Haemophilus Infections / Q000382:microbiology*; D006193:Haemophilus influenzae / Q000302:isolation & purification*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000382:microbiology*; D011625:Pterygium / Q000601:surgery*