title: Chromenopyridines: promising scaffolds for medicinal and biological chemistry.
abstract: Chromenopyridines constitute a structurally diverse class of compounds with a wide range of bioactivities and increasing presence in drugs. Here we analyze the scope of the synthetic methodology to access this nucleus with emphasis on multicomponent reactions and robust methodologies. Reactivity issues, medicinal applications and other properties are also reviewed.
authors.affiliation: Bioelectrochemistry Laboratory, Faculty of Chemical and Pharmaceutical Sciences, University of Chile, Sergio Livingstone Polhammer 1007, Santiago-Chile. lnunezv@ciq.uchile.cl
authors.forename: L J
authors.initials: LJ
authors.lastname: Núñez-Vergara
authors.forename: J A
authors.initials: JA
authors.lastname: Squella
authors.forename: P A
authors.initials: PA
authors.lastname: Navarrete-Encina
authors.forename: E
authors.initials: E
authors.lastname: Vicente-García
authors.forename: S
authors.initials: S
authors.lastname: Preciado
authors.forename: R
authors.initials: R
authors.lastname: Lavilla
mesh_terms: D000900:Anti-Bacterial Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D000893:Anti-Inflammatory Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D001578:Benzopyrans / Q000737:chemistry; D006801:Humans; D009942:Organometallic Compounds / Q000737:chemistry; D010720:Phosphines / Q000737:chemistry; D011725:Pyridines / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D000893:Anti-Inflammatory Agents; D001578:Benzopyrans; D009942:Organometallic Compounds; D010720:Phosphines; D011725:Pyridines; C044646:phosphine