title: Autophagy: cellular defense to excessive inflammation.
abstract: Autophagy can orchestrate a variety of cellular responses to dangerous stimuli. Our understanding of the physiologic roles of autophagy has recently expanded; in addition to its other roles, autophagy now appears to play an essential role in regulating inflammatory responses. This review describes recent findings concerning the roles and mechanisms of autophagy in controlling excessive inflammation.
authors.affiliation: Department of Microbiology, College of Medicine, Chungnam National University, 6 Munhwa-dong, Jungku, Daejeon 301-747, South Korea. hayoungj@cnu.ac.kr
authors.forename: Eun-Kyeong
authors.initials: EK
authors.lastname: Jo
authors.forename: Dong-Min
authors.initials: DM
authors.lastname: Shin
authors.forename: Augustine M K
authors.initials: AM
authors.lastname: Choi
mesh_terms: D000818:Animals; D001343:Autophagy / Q000276:immunology* / Q000502:physiology; D006801:Humans; D007111:Immunity, Cellular / Q000276:immunology*; D007249:Inflammation / Q000276:immunology* / Q000517:prevention & control; D015398:Signal Transduction / Q000276:immunology