title: [Simulation of parameters of alcohol-oxidizing enzyme systems and pathomorphological characteristics in situations of acute ethanol poisoning and ischemic heart disease].
abstract: Morphometric characteristics and forensic chemical information used in diagnostics of acute ethanol intoxication and coronary heart disease in conjunction with macro- and microscopic pathomorphological signs of the changes in the heart, liver, and kidneys provide data that may suggest the presence of pathology but do not permit to reliably identify it. In this context, evaluation of activities of alcohol-oxidizing enzyme systems acquires clinical significance. The analysis of correlations between quantitative parameters supplemented by the construction of binary models allows to objectively interpret the conclusions about the cause of death in each concrete case of acute ethanol poisoning and coronary heart disease.
authors.forename: V A
authors.initials: VA
authors.lastname: Porodenko
authors.forename: V T
authors.initials: VT
authors.lastname: Korkhmazov
mesh_terms: D000208:Acute Disease; D000426:Alcohol Dehydrogenase / Q000378:metabolism; D000435:Alcoholic Intoxication / Q000150:complications / Q000201:enzymology* / Q000473:pathology*; D002374:Catalase / Q000378:metabolism; D003627:Data Interpretation, Statistical; D000431:Ethanol / Q000097:blood / Q000506:poisoning* / Q000652:urine; D049429:Forensic Pathology; D053593:Forensic Toxicology; D006801:Humans; D008954:Models, Biological; D017202:Myocardial Ischemia / Q000150:complications / Q000201:enzymology* / Q000473:pathology*; D009252:NADPH Dehydrogenase / Q000378:metabolism; D009195:Peroxidase / Q000378:metabolism
chemical_list: D000431:Ethanol; D000426:Alcohol Dehydrogenase; D002374:Catalase; D009195:Peroxidase; D009252:NADPH Dehydrogenase