title: The galvanizing of Mycobacterium tuberculosis: an antimicrobial mechanism.
abstract: Evolving under constant threat from invading microbes, macrophages have acquired multiple means of killing bacteria. In this issue of Cell Host & Microbe, Botella and colleagues (Botella et al., 2011) describe a novel antimicrobial mechanism based on elevated levels of intraphagosomal Zn(2+) and the corresponding induction of bacterial genes to ameliorate this host-derived stress.
authors.affiliation: Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY 14850, USA.
authors.forename: David G
authors.initials: DG
authors.lastname: Russell
mesh_terms: D000818:Animals; D025243:Bacterial Proton-Translocating ATPases / Q000378:metabolism*; D005260:Female; D006801:Humans; D008264:Macrophages / Q000378:metabolism*; D009169:Mycobacterium tuberculosis / Q000201:enzymology*; D014376:Tuberculosis / Q000378:metabolism*; D015032:Zinc / Q000378:metabolism*
chemical_list: D025243:Bacterial Proton-Translocating ATPases; D015032:Zinc