title: Co-operative transport by molecular motors.
abstract: Intracellular transport is often driven co-operatively by several molecular motors, which may belong to one or several motor species. Understanding how these motors interact and what co-ordinates and regulates their movements is a central problem in studies of intracellular transport. A general theoretical framework for the analysis of such transport processes is described, which enables us to explain the behaviour of intracellular cargos by the transport properties of individual motors and their interactions. We review recent advances in the theoretical description of motor co-operativity and discuss related experimental results.
authors.affiliation: Max Planck Institute of Colloids and Interfaces, 14424 Potsdam, Germany. florian.berger@mpikg.mpg.de
authors.forename: Florian
authors.initials: F
authors.lastname: Berger
authors.forename: Corina
authors.initials: C
authors.lastname: Keller
authors.forename: Melanie J I
authors.initials: MJ
authors.lastname: Müller
authors.forename: Stefan
authors.initials: S
authors.lastname: Klumpp
authors.forename: Reinhard
authors.initials: R
authors.lastname: Lipowsky
mesh_terms: D001692:Biological Transport / Q000502:physiology*; D008870:Microtubules / Q000378:metabolism; D008954:Models, Biological; D020409:Molecular Motor Proteins / Q000378:metabolism*
chemical_list: D020409:Molecular Motor Proteins