title: Comparison of invasive and non-invasive measurements of haemodynamic parameters in patients with advanced heart failure.
abstract: OBJECTIVE
  Measurement of haemodynamic parameters using a Swan-Ganz catheter is of clinical importance in patients with advanced heart failure; however, its applicability is limited due to its invasiveness. The aim of the study was to estimate the concordance between invasive and non-invasive measurements of haemodynamic parameters in patients with advanced heart failure.
  
  
  RESULTS
  We examined 25 patients with advanced heart failure (20 men, age: 64 ± 11 years, New York Heart Association class III/IV: 88/12%, left ventricular ejection fraction: 37 ± 20%), 13 (52%) demonstrated decompensated heart failure. Resting haemodynamic parameters were measured simultaneously using two methods: an invasive Swan-Ganz catheterization and a thermodilution technique; and a non-invasive recording using a device for finger arterial pressure waveform analysis. The following parameters were analysed: stroke volume (SV, ml), cardiac output (CO, l/min) and systemic vascular resistance (SVR, dyne × s/cm⁵). The concordance between these two methods was assessed using the variability coefficient calculated according to a Bland-Altman method. Comparing the invasive and non-invasive measures, variability coefficients were: 13, 18 and 11% for SV, SVR and CO, respectively. Similar variability coefficients were obtained when invasive and non-invasive measurements were compared in prespecified subgroups of patients, distinguished based on the presence of decompensation, atrial fibrillation and values of SBP.
  
  
  CONCLUSIONS
  Evaluation of haemodynamic parameters using a non-invasive method based on a pressure pulse contour model reveals an adequate concordance with the measures obtained using an invasive approach. Our results suggest that a non-invasive method for haemodynamic monitoring could be applied in clinical practice in patients with advanced heart failure.
authors.affiliation: Department of Heart Diseases, Wroclaw Medical University, Wroclaw, Poland. matsok@gmail.com
authors.forename: Mateusz
authors.initials: M
authors.lastname: Sokolski
authors.forename: Agnieszka
authors.initials: A
authors.lastname: Rydlewska
authors.forename: Bartosz
authors.initials: B
authors.lastname: Krakowiak
authors.forename: Jan
authors.initials: J
authors.lastname: Biegus
authors.forename: Robert
authors.initials: R
authors.lastname: Zymlinski
authors.forename: Waldemar
authors.initials: W
authors.lastname: Banasiak
authors.forename: Ewa Anita
authors.initials: EA
authors.lastname: Jankowska
authors.forename: Piotr
authors.initials: P
authors.lastname: Ponikowski
mesh_terms: D000368:Aged; D001794:Blood Pressure; D001795:Blood Pressure Determination / Q000379:methods*; D002302:Cardiac Output; D002407:Catheterization, Swan-Ganz; D005260:Female; D005385:Fingers / Q000098:blood supply*; D006333:Heart Failure / Q000175:diagnosis* / Q000503:physiopathology; D006439:Hemodynamics; D006801:Humans; D008297:Male; D008875:Middle Aged; D011044:Poland; D011237:Predictive Value of Tests; D011379:Prognosis; D013318:Stroke Volume; D013815:Thermodilution; D014655:Vascular Resistance