title: Urinary incontinence following deep brain stimulation of the pedunculopontine nucleus.
abstract: Low-frequency deep brain stimulation (DBS) of the pedunculopontine nucleus (PPN) has been reported to improve akinesia and gait difficulties in patients with Parkinson's disease (PD). We report on a patient with PD and L: -dopa refractory gait symptoms who developed detrusor over-activity immediately after right PPN DBS. Proximity between caudal PPN and brainstem structures implicated in control of micturition is a possible explanation.
authors.affiliation: Unit of Functional Neurosurgery, Sobell Department of Motor Neuroscience and Movement Disorders, UCL Institute of Neurology, Queen Square, London, WC1N 3BG, UK. i.olmos@ion.ucl.ac.uk
authors.forename: Iciar
authors.initials: I
authors.lastname: Aviles-Olmos
authors.forename: Thomas
authors.initials: T
authors.lastname: Foltynie
authors.forename: Jalesh
authors.initials: J
authors.lastname: Panicker
authors.forename: Dorothy
authors.initials: D
authors.lastname: Cowie
authors.forename: Patricia
authors.initials: P
authors.lastname: Limousin
authors.forename: Marwan
authors.initials: M
authors.lastname: Hariz
authors.forename: Clare J
authors.initials: CJ
authors.lastname: Fowler
authors.forename: Ludvic
authors.initials: L
authors.lastname: Zrinzo
mesh_terms: D000368:Aged; D046690:Deep Brain Stimulation / Q000009:adverse effects* / Q000295:instrumentation / Q000379:methods; D006801:Humans; D007431:Intraoperative Complications / Q000209:etiology / Q000503:physiopathology*; D008297:Male; D010300:Parkinson Disease / Q000503:physiopathology / Q000628:therapy*; D045042:Pedunculopontine Tegmental Nucleus / Q000503:physiopathology / Q000601:surgery*; D014549:Urinary Incontinence / Q000209:etiology* / Q000503:physiopathology; D014554:Urination / Q000502:physiology*