title: Management of epidermolysis bullosa acquisita.
abstract: Epidermolysis bullosa acquisita is a rare and debilitating autoimmune mucocutaneous blistering disease caused by autoantibodies directed against type VII collagen or anchoring fibrils in the subepidermal basement membrane zone. Treatment is quite challenging because this disease can be recalcitrant to multiple modalities. This article discusses the current management of this disease.
authors.affiliation: Department of Dermatology, James Laws House, St George Hospital, Gray Street, Kogarah, Sydney, NSW 2217, Australia.
authors.forename: Lizbeth R A
authors.initials: LR
authors.lastname: Intong
authors.forename: Dédée F
authors.initials: DF
authors.lastname: Murrell
mesh_terms: D058846:Antibodies, Monoclonal, Murine-Derived / Q000627:therapeutic use; D001323:Autoantibodies / Q000276:immunology; D001327:Autoimmune Diseases / Q000188:drug therapy / Q000276:immunology; D002908:Chronic Disease; D003078:Colchicine / Q000627:therapeutic use; D024143:Collagen Type VII / Q000276:immunology; D016572:Cyclosporine / Q000627:therapeutic use; D003622:Dapsone / Q000627:therapeutic use; D003879:Dermatologic Agents / Q000627:therapeutic use; D016107:Epidermolysis Bullosa Acquisita / Q000188:drug therapy* / Q000276:immunology / Q000628:therapy; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008297:Male; D009173:Mycophenolic Acid / Q000031:analogs & derivatives / Q000627:therapeutic use; D010778:Photochemotherapy; D010956:Plasmapheresis; D000069283:Rituximab; D013427:Sulfapyridine / Q000627:therapeutic use; D012460:Sulfasalazine / Q000627:therapeutic use
chemical_list: D058846:Antibodies, Monoclonal, Murine-Derived; D001323:Autoantibodies; D024143:Collagen Type VII; D003879:Dermatologic Agents; D016756:Immunoglobulins, Intravenous; D007166:Immunosuppressive Agents; D012460:Sulfasalazine; D000069283:Rituximab; D016572:Cyclosporine; D003622:Dapsone; D009173:Mycophenolic Acid; D003078:Colchicine; D013427:Sulfapyridine