title: Psychiatric comorbidities in women with celiac disease.
abstract: OBJECTIVE
  Although the physical consequences of Celiac Disease are well studied, less is known about co-occurring psychiatric symptoms. This study examines psychiatric risk and comorbidities of women with Celiac Disease, who may be at increased risk for psychiatric symptoms (e.g. depression, and disordered eating behaviours).
  
  
  METHODS
  Women (N = 177) with Celiac Disease responded to an extensive web-mediated survey assessing dietary compliance, illness symptoms, psychiatric functioning, and disordered eating.
  
  
  RESULTS
  Despite high reported dietary compliance, patients reported marked illness symptoms and impaired quality of life. A substantial minority endorsed symptoms that met criteria for the diagnosis of psychiatric disorders: 37% (n = 65) met the threshold suggesting depression, and 22% (n = 39) for disordered eating. Participants whose symptoms exceeded these clinical thresholds reported greater perceived stress and reduced overall mental health, relative to women below the clinical cutoffs.
  
  
  CONCLUSIONS
  Despite largely adhering to a gluten-free diet, a substantial subset of women with Celiac Disease report clinically relevant symptoms of depression and disordered eating; such symptoms are associated with increased psychosocial distress in other domains. These results suggest potential to improve the patient well-being through attention to psychosocial care, in addition to existing dietary recommendations for individuals with Celiac Disease.
authors.affiliation: Department of Psychology, Syracuse University, Syracuse, NY, USA.
authors.forename: Danielle
authors.initials: D
authors.lastname: Arigo
authors.forename: Alicia M
authors.initials: AM
authors.lastname: Anskis
authors.forename: Joshua M
authors.initials: JM
authors.lastname: Smyth
mesh_terms: D000328:Adult; D002446:Celiac Disease / Q000178:diet therapy / Q000453:epidemiology* / Q000523:psychology*; D002908:Chronic Disease; D015897:Comorbidity; D003863:Depression / Q000453:epidemiology*; D055050:Diet, Gluten-Free; D001068:Feeding and Eating Disorders / Q000453:epidemiology*; D005260:Female; D006305:Health Status Indicators; D006306:Health Surveys; D006801:Humans; D010349:Patient Compliance / Q000706:statistics & numerical data; D011788:Quality of Life; D013315:Stress, Psychological; D055815:Young Adult