title: Transfer-printing of single DNA molecule arrays on graphene for high-resolution electron imaging and analysis.
abstract: Graphene represents the ultimate substrate for high-resolution transmission electron microscopy, but the deposition of biological samples on this highly hydrophobic material has until now been a challenge. We present a reliable method for depositing ordered arrays of individual elongated DNA molecules on single-layer graphene substrates for high-resolution electron beam imaging and electron energy loss spectroscopy analysis. This method is a necessary step toward the observation of single elongated DNA molecules with single base spatial resolution to directly read genetic and epigenetic information.
authors.affiliation: School of Applied and Engineering Physics, Cornell University , Ithaca, New York 14853, United States. ac675@cornell.edu
authors.forename: Aline
authors.initials: A
authors.lastname: Cerf
authors.forename: Thomas
authors.initials: T
authors.lastname: Alava
authors.forename: Robert A
authors.initials: RA
authors.lastname: Barton
authors.forename: Harold G
authors.initials: HG
authors.lastname: Craighead