title: [Thoughts about thromboembolic events prophylaxis in cancer patients].
abstract: The risk of venous thromboembolic events (VTE) in cancer patients is higher than in the general population. Treatment may also increase this risk in these patients. Based on the appropriate criteria (of which the most important are the current ministerial guidelines) thrombosis prophylaxis should be started (given that there is no contraindication) on these patients and be continued while they are at risk. In the event of permanent risk thrombosis prophylaxis should be given lifelong. The drug of choice is low-molecular-weight heparin (LMWH) which is safer and more effective than the oral vitamin K antagonists. Platelet aggregation inhibitors have proved unsuccessful in this patient group. The evidence so far suggests that LMWH (during VTE prophylaxis) can have a positive impact on the course of cancer and perhaps it will be registered under the indication section for cancer patients in the future.
authors.affiliation: Megyei Onkológiai Központ, Békés Megyei Képviselõtestület Pándy Kálmán Kórháza, Gyula, Hungary. dr.piko.bela@gmail.com
authors.forename: Béla
authors.initials: B
authors.lastname: Pikó
authors.forename: Ildiko Maria
authors.initials: IM
authors.lastname: Kremer
authors.forename: Pal
authors.initials: P
authors.lastname: Rahoty
authors.forename: Ali
authors.initials: A
authors.lastname: Bassam
authors.forename: Sándor
authors.initials: S
authors.lastname: Dimák
authors.forename: Anita
authors.initials: A
authors.lastname: Kis
authors.forename: Margit
authors.initials: M
authors.lastname: Csiffári
authors.forename: Paul
authors.initials: P
authors.lastname: Rus-Gal
authors.forename: Zsolt
authors.initials: Z
authors.lastname: Szabó
authors.forename: Blanka
authors.initials: B
authors.lastname: Veréb
authors.forename: Janos
authors.initials: J
authors.lastname: Zsilak
mesh_terms: D000925:Anticoagulants / Q000627:therapeutic use*; D006495:Heparin, Low-Molecular-Weight / Q000627:therapeutic use*; D006801:Humans; D009369:Neoplasms / Q000150:complications*; D018570:Risk Assessment; D012307:Risk Factors; D013923:Thromboembolism / Q000209:etiology / Q000517:prevention & control; D016896:Treatment Outcome; D054556:Venous Thromboembolism / Q000139:chemically induced / Q000209:etiology* / Q000517:prevention & control*; D020246:Venous Thrombosis / Q000209:etiology / Q000517:prevention & control; D014812:Vitamin K / Q000037:antagonists & inhibitors*
chemical_list: D000925:Anticoagulants; D006495:Heparin, Low-Molecular-Weight; D014812:Vitamin K