title: Poststeroid panniculitis in an adult.
abstract: Poststeroid panniculitis is a rare disorder usually reported in children after a sudden decrease or withdrawal of corticosteroid therapy. We report a case in an adult, a finding very rarely reported in English literature. The case report is about a 34-year-old man with multiple erythematous, firm and tender subcutaneous nodules on both thighs and legs after the withdrawal of long-term doses of dexamethasone prescribed before and after surgery for a frontoinsular anaplastic oligodendroglioma. Histopathologic study revealed mainly lobular and also septal panniculitis with fat necrosis and characteristic needle-shaped clefts in radial arrangement within fat cells and multinucleated giant cells. The lesions resolved in about 5 months, after weight loss and application of topical corticosteroids for 1 month, leaving only residual hyperpigmentation.
authors.affiliation: Department of Dermatology, Universitary Hospitalary Complex Coruña, A Coruña, Spain. ana.de.andres.del.rosario@sergas.es
authors.forename: Ana
authors.initials: A
authors.lastname: de-Andrés-del-Rosario
authors.forename: María Magdalena
authors.initials: MM
authors.lastname: Verea-Hernando
authors.forename: María Teresa
authors.initials: MT
authors.lastname: Yebra-Pimentel
authors.forename: Laura
authors.initials: L
authors.lastname: Rosende-Maceiras
authors.forename: Francisca
authors.initials: F
authors.lastname: Piñeyro-Molina
authors.forename: Eduardo Fonseca
authors.initials: EF
authors.lastname: Capdevila
mesh_terms: D000305:Adrenal Cortex Hormones / Q000009:adverse effects*; D000328:Adult; D018931:Antineoplastic Agents, Hormonal / Q000009:adverse effects; D001932:Brain Neoplasms / Q000628:therapy; D003131:Combined Modality Therapy; D003907:Dexamethasone / Q000009:adverse effects*; D006801:Humans; D008297:Male; D009837:Oligodendroglioma / Q000628:therapy; D015434:Panniculitis / Q000139:chemically induced* / Q000473:pathology*
chemical_list: D000305:Adrenal Cortex Hormones; D018931:Antineoplastic Agents, Hormonal; D003907:Dexamethasone