title: De novo chromosomal translocation t(3;5)(q13;q35) in an infertile man.
abstract: Chromosomal rearrangements are rare structural abnormalities that are usually associated with male infertility or sterility. We describe here the clinical and cytogenetic studies carried out in a couple with repeated abortions. Cytogenetic analysis of the male partner showed a de novo chromosomal translocation t(3;5)(q13;q35) which could be involved in the meiotic errors resulting in reproductive failure.
authors.affiliation: Institute of Genetics and Hospital for Genetic Diseases, Osmania University, Begumpet, Hyderabad, India. venkateshwari@yahoo.com
authors.forename: A
authors.initials: A
authors.lastname: Venkateshwari
authors.forename: A
authors.initials: A
authors.lastname: Srilekha
authors.forename: A
authors.initials: A
authors.lastname: Begum
authors.forename: M
authors.initials: M
authors.lastname: Sujatha
authors.forename: T
authors.initials: T
authors.lastname: Sunitha
authors.forename: P
authors.initials: P
authors.lastname: Nallari
authors.forename: A
authors.initials: A
authors.lastname: Jyothy
mesh_terms: D000026:Abortion, Habitual; D000328:Adult; D002893:Chromosomes, Human, Pair 3; D002895:Chromosomes, Human, Pair 5; D005260:Female; D006801:Humans; D007248:Infertility, Male / Q000235:genetics*; D007621:Karyotyping; D008297:Male; D014178:Translocation, Genetic