title: Revealing human ocular dominance columns using high-resolution functional magnetic resonance imaging.
abstract: In this review, I will recall some events at the time when we conducted a high-resolution functional magnetic resonance imaging (fMRI) study mapping ocular dominance columns in humans (Cheng et al., 2001). In particular, I will comment on why and how we had to deal with several key issues in the experimental procedure that we developed in this study, including the adoption of prolonged monocular stimulation, the treatment of large surface veins and the prescription of imaging slice on selected subjects. I will then touch upon several key developments after our work was published and give my thoughts on the challenges that the field of high-resolution fMRI faces.
authors.affiliation: Support Unit for Functional Magnetic Resonance Imaging, and Laboratory for Cognitive Brain Mapping, RIKEN Brain Science Institute, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan. kcheng@postman.riken.jp
authors.forename: Kang
authors.initials: K
authors.lastname: Cheng
mesh_terms: D001921:Brain / Q000033:anatomy & histology* / Q000502:physiology; D001931:Brain Mapping / Q000266:history* / Q000379:methods; D023882:Dominance, Ocular / Q000502:physiology*; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000266:history* / Q000379:methods; D008279:Magnetic Resonance Imaging / Q000266:history* / Q000379:methods; D014796:Visual Perception / Q000502:physiology