title: Effectiveness of Biobrane for treatment of partial-thickness burns in children.
abstract: OBJECTIVE
  Wound care for partial-thickness burns should alleviate pain, decrease hospital length of stay, and be readily applied to a variety of wounds. The effectiveness of Biobrane (UDL Laboratories, Rockford, IL) is compared with that of Beta Glucan Collagen (BGC; Brennan Medical, St. Paul, MN) in a retrospective cohort study.
  
  
  METHODS
  A retrospective chart review of all children treated at a tertiary care pediatric hospital between 2003 and 2009 identified patients with partial-thickness burns treated with Biobrane. These patients were compared with historical controls treated with BGC.
  
  
  RESULTS
  A total of 235 children between the ages of 4 weeks and 18 years with an average of 6.0% body surface area partial-thickness burns were treated with Biobrane. In a multivariate statistical analysis, patients treated with Biobrane healed significantly faster than those treated with BGC (Biobrane vs BGC: median, 9 vs 13 days; P = .019; hazard ratio, 1.68). In addition, patients who required inpatient treatment trended toward having shorter length of hospital stay in the Biobrane group (2.6 vs 4.1 days, P = .079).
  
  
  CONCLUSIONS
  Partial-thickness burn care consists of early debridement and application of a burn wound dressing. Biobrane dressings result in faster healing compared with BGC and may decrease hospital length of stay for patients requiring inpatient admission.
authors.affiliation: Division of Pediatric Surgery, Department of Surgery, Medical University of South Carolina, Charleston, SC 29425-6130, USA.
authors.forename: Aaron P
authors.initials: AP
authors.lastname: Lesher
authors.forename: Ryan H
authors.initials: RH
authors.lastname: Curry
authors.forename: Jill
authors.initials: J
authors.lastname: Evans
authors.forename: Valerie A
authors.initials: VA
authors.lastname: Smith
authors.forename: Michael T
authors.initials: MT
authors.lastname: Fitzgerald
authors.forename: Robert A
authors.initials: RA
authors.lastname: Cina
authors.forename: Christian J
authors.initials: CJ
authors.lastname: Streck
authors.forename: Andre V
authors.initials: AV
authors.lastname: Hebra
mesh_terms: D000293:Adolescent; D002056:Burns / Q000473:pathology / Q000628:therapy*; D002648:Child; D002675:Child, Preschool; D020099:Coated Materials, Biocompatible / Q000627:therapeutic use*; D003094:Collagen / Q000627:therapeutic use*; D006801:Humans; D007223:Infant; D009779:Occlusive Dressings; D012189:Retrospective Studies; D014945:Wound Healing; D047071:beta-Glucans / Q000627:therapeutic use*
chemical_list: C042816:Biobrane; D020099:Coated Materials, Biocompatible; D047071:beta-Glucans; C420647:beta-glucan collagen; D003094:Collagen