title: Tissue-specific expression of FLOWERING LOCUS T in Arabidopsis is maintained independently of polycomb group protein repression.
abstract: The Polycomb Group (PcG) pathway represses transcription through a mechanism conserved among plants and animals. PcG-mediated repression can determine spatial territories of gene expression, but it remains unclear whether PcG-mediated repression is a regulatory requirement for all targets. Here, we show the role of PcG proteins in the spatial regulation of FLOWERING LOCUS T (FT), a main activator of flowering in Arabidopsis thaliana exclusively expressed in the vasculature. Strikingly, the loss of PcG repression causes down-regulation of FT. In addition, our results show how the effect of PcG-mediated regulation differs for target genes and that, for FT expression, it relies primarily on tissue differentiation.
authors.affiliation: Max Planck Institute for Plant Breeding Research, 50829 Cologne, Germany.
authors.forename: Sara
authors.initials: S
authors.lastname: Farrona
authors.forename: Frazer L
authors.initials: FL
authors.lastname: Thorpe
authors.forename: Julia
authors.initials: J
authors.lastname: Engelhorn
authors.forename: Jessika
authors.initials: J
authors.lastname: Adrian
authors.forename: Xue
authors.initials: X
authors.lastname: Dong
authors.forename: Liron
authors.initials: L
authors.lastname: Sarid-Krebs
authors.forename: Justin
authors.initials: J
authors.lastname: Goodrich
authors.forename: Franziska
authors.initials: F
authors.lastname: Turck
mesh_terms: D017360:Arabidopsis / Q000235:genetics* / Q000378:metabolism; D029681:Arabidopsis Proteins / Q000235:genetics / Q000378:metabolism*; D002843:Chromatin / Q000378:metabolism; D016000:Cluster Analysis; D015536:Down-Regulation; D035264:Flowers / Q000235:genetics / Q000254:growth & development*; D018506:Gene Expression Regulation, Plant; D006657:Histones / Q000378:metabolism; D020411:Oligonucleotide Array Sequence Analysis; D063146:Polycomb-Group Proteins; D018749:RNA, Plant / Q000235:genetics; D012097:Repressor Proteins / Q000378:metabolism*; D014158:Transcription, Genetic; D059467:Transcriptome
chemical_list: D029681:Arabidopsis Proteins; D002843:Chromatin; C418905:FT protein, Arabidopsis; D006657:Histones; D063146:Polycomb-Group Proteins; D018749:RNA, Plant; D012097:Repressor Proteins