title: Wt1 flip-flops chromatin in a CTCF domain.
abstract: CTCF plays diverse roles in nuclear organization and transcriptional regulation. In this issue of Developmental Cell, Essafi et al. (2011) report a mechanism by which the repressive or active state of chromatin in a domain defined by CTCF can be switched by the Wt1 transcription factor to regulate gene expression.
authors.affiliation: Department of Biology, Emory University, Atlanta, GA 30322, USA.
authors.forename: B V
authors.initials: BV
authors.lastname: Gurudatta
authors.forename: Victor G
authors.initials: VG
authors.lastname: Corces