title: Organochlorine pesticide residue levels in blood serum of inhabitants from Veracruz, Mexico.
abstract: The objective of the present study was to monitor the levels of organochlorine pesticides HCB; α-, β-, γ-HCH; pp'DDE; op'DDT; and pp'DDT in blood serum of Veracruz, Mexico inhabitants. Organochlorine pesticides were analyzed in 150 blood serum samples that constituted that which remained after clinical analyses, using gas chromatography-electron-capture detection (GC-ECD). The results were expressed as milligrams per kilogram on fat basis and micrograms per liter on wet weight. Only the following pesticides were detected: p,p'-DDE was the major organochlorine component, detected in 100% of samples at mean 15.8 mg/kg and 8.4 μg/L; p,p'-DDT was presented in 41.3.% of monitored samples at mean 3.1 mg/kg and 1.4 μg/L; β-HCH was found in 48.6% of the samples at mean 4.9 mg/kg and 2.7 μg/L; op'DDT was determined to be in only 3.3% of monitored samples at mean 2.7 mg/kg and 1.4 μg/L. The pooled samples divided according to sex showed significant differences of β-HCH and pp'DDE concentrations in females. The samples grouped according to age presented the third tertile as more contaminated in both sexes, indicating age as a positively associated factor with serum organochlorine pesticide levels in Veracruz inhabitants.
authors.affiliation: Institute of Forensic Medicine, University of Veracruz, SS Juan Pablo II s/n, 91980 Boca del Río, Veracruz, Mexico. swal@uv.mx
authors.forename: Stefan M
authors.initials: SM
authors.lastname: Waliszewski
authors.forename: M
authors.initials: M
authors.lastname: Caba
authors.forename: M
authors.initials: M
authors.lastname: Herrero-Mercado
authors.forename: H
authors.initials: H
authors.lastname: Saldariaga-Noreña
authors.forename: E
authors.initials: E
authors.lastname: Meza
authors.forename: R
authors.initials: R
authors.lastname: Zepeda
authors.forename: C
authors.initials: C
authors.lastname: Martínez-Valenzuela
authors.forename: S
authors.initials: S
authors.lastname: Gómez Arroyo
authors.forename: R
authors.initials: R
authors.lastname: Villalobos Pietrini
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D003634:DDT / Q000097:blood; D003633:Dichlorodiphenyl Dichloroethylene / Q000097:blood; D004781:Environmental Exposure / Q000032:analysis / Q000706:statistics & numerical data*; D004785:Environmental Pollutants / Q000097:blood*; D005260:Female; D006581:Hexachlorobenzene / Q000097:blood; D001556:Hexachlorocyclohexane / Q000097:blood; D006801:Humans; D006843:Hydrocarbons, Chlorinated / Q000097:blood*; D008297:Male; D008800:Mexico; D008875:Middle Aged; D010575:Pesticides / Q000097:blood*; D055815:Young Adult
chemical_list: D004785:Environmental Pollutants; D006843:Hydrocarbons, Chlorinated; D010575:Pesticides; D003633:Dichlorodiphenyl Dichloroethylene; D006581:Hexachlorobenzene; D001556:Hexachlorocyclohexane; D003634:DDT; C023888:beta-hexachlorocyclohexane