title: Palladium-catalyzed enantioselective desymmetrization of silacyclobutanes: construction of silacycles possessing a tetraorganosilicon stereocenter.
abstract: A palladium-catalyzed desymmetrization of alkyne-tethered silacyclobutanes to give silacycles possessing a tetraorganosilicon stereocenter has been developed, and high chemo- and enantioselectivities have been achieved by the use of a newly synthesized chiral phosphoramidite ligand.
authors.affiliation: Department of Chemistry, Graduate School of Science, Kyoto University, Sakyo, Kyoto 606-8502, Japan. shintani@kuchem.kyoto-u.ac.jp
authors.forename: Ryo
authors.initials: R
authors.lastname: Shintani
authors.forename: Kohei
authors.initials: K
authors.lastname: Moriya
authors.forename: Tamio
authors.initials: T
authors.lastname: Hayashi
mesh_terms: D002384:Catalysis; D018360:Crystallography, X-Ray; D008958:Models, Molecular; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D017646:Organosilicon Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D010165:Palladium / Q000737:chemistry*; D012821:Silanes / Q000138:chemical synthesis* / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D009942:Organometallic Compounds; D017646:Organosilicon Compounds; D012821:Silanes; D010165:Palladium