title: Resistance exercise inter-set cooling strategy: effect on performance and muscle damage.
abstract: OBJECTIVE
  To compare the effect of inter-set cooling and no cooling during resistance exercise (RE) on the total repetitions and select muscle damage biomarker responses.
  
  
  METHODS
  Sixteen healthy men volunteered to participate in this study and were randomly assigned to Cooling (n = 8) or Control (n = 8) groups. They performed a RE protocol consisting of four sets of biceps curl at 80% of 1RM. The cooling group received the application of wet bags of ice during each interest rest interval (Cooling), while the Control realized the same protocol without ice application. Exercise was performed to voluntary fatigue and the numbers of repetitions per set were recorded. Subjects provided blood samples before and at 24, 48, and 72 h following RE to evaluate serum CK activity and myoglobin concentration.
  
  
  RESULTS
  The Cooling group produced a greater number of repetitions (approx. 21%) than did the Control, but there were no differences in serum CK activity and myoglobin responses between the groups.
  
  
  CONCLUSIONS
  Incorporating inter-set external cooling augments the number of repetitions per set during RE without inducing an additional muscle damage biomarker response.
authors.affiliation: Laboratory of Human Movement Studies, University Foundation of Itaperuna, Itaperuna, Brazil.
authors.forename: Pedro
authors.initials: P
authors.lastname: Galoza
authors.forename: Felipe
authors.initials: F
authors.lastname: Sampaio-Jorge
authors.forename: Marco
authors.initials: M
authors.lastname: Machado
authors.forename: Ricardo
authors.initials: R
authors.lastname: Fonseca
authors.forename: Pierre A V
authors.initials: PA
authors.lastname: Silva
mesh_terms: D000704:Analysis of Variance; D001265:Athletic Injuries / Q000517:prevention & control*; D054874:Athletic Performance / Q000502:physiology*; D015415:Biomarkers / Q000097:blood; D003080:Cold Temperature; D003402:Creatine Kinase / Q000097:blood; D006801:Humans; D008297:Male; D018482:Muscle, Skeletal / Q000293:injuries*; D009211:Myoglobin / Q000097:blood; D055070:Resistance Training; D055815:Young Adult
chemical_list: D015415:Biomarkers; D009211:Myoglobin; D003402:Creatine Kinase