title: A deep cavitand with a fluorescent wall functions as an ion sensor.
abstract: The synthesis and characterization of a deep cavitand bearing a fluorescent benzoquinoxaline wall is reported. Noncovalent host-guest recognition events are exploited to sense small charged molecules including acetylcholine. The cavitand also exhibits an anion dependent change in fluorescence that is used to differentiate halide ions in solution.
authors.affiliation: The Skaggs Institute for Chemical Biology and Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA.
authors.forename: Orion B
authors.initials: OB
authors.lastname: Berryman
authors.forename: Aaron C
authors.initials: AC
authors.lastname: Sather
authors.forename: Julius
authors.initials: J
authors.lastname: Rebek
mesh_terms: D004988:Ethers, Cyclic / Q000032:analysis / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000032:analysis / Q000737:chemistry*; D007477:Ions / Q000032:analysis; D008958:Models, Molecular; D015394:Molecular Structure; D012118:Resorcinols / Q000032:analysis / Q000737:chemistry*
chemical_list: D004988:Ethers, Cyclic; D005456:Fluorescent Dyes; D007477:Ions; D012118:Resorcinols; C442939:cavitand