title: Plunging ranula intruding into the parapharyngeal space treated with OK-432.
abstract: We report a very rare case of a plunging ranula extending into the parapharyngeal space, which was treated successfully with OK-432. A 27-year-old woman presented with a 4-month history of right submandibular swelling. Based on computed tomography and magnetic resonance imaging findings, we established a diagnosis of plunging ranula intruding into the parapharyngeal space. The patient was treated with an intracystic OK-432 injection that was administered under ultrasonographic guidance. At 6 weeks after the injection, computed tomography showed complete disappearance of the cystic mass. No recurrence was noted during the 10-month follow-up.
authors.affiliation: Department of Otolaryngology, National Hospital Organization Disaster Medical Center, Tokyo, Japan. kinoshitam-zao@umin.ac.jp
authors.forename: Makoto
authors.initials: M
authors.lastname: Kinoshita
authors.forename: Wataru
authors.initials: W
authors.lastname: Kida
authors.forename: Haruka
authors.initials: H
authors.lastname: Nakahara
mesh_terms: D000328:Adult; D000970:Antineoplastic Agents / Q000008:administration & dosage; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015552:Injections, Intralesional; D008279:Magnetic Resonance Imaging; D010608:Pharyngeal Diseases / Q000175:diagnosis / Q000188:drug therapy*; D010614:Pharynx; D010844:Picibanil / Q000008:administration & dosage*; D011900:Ranula / Q000175:diagnosis / Q000188:drug therapy*; D014057:Tomography, X-Ray Computed
chemical_list: D000970:Antineoplastic Agents; D010844:Picibanil