title: Application of criteria developed by the Task Force on Neonatal Encephalopathy and Cerebral Palsy to acutely asphyxiated neonates.
abstract: OBJECTIVE
  To estimate whether term neonates with acute intrapartum hypoxic ischemic encephalopathy and permanent brain injury satisfied the criteria for causation of cerebral palsy developed by the Task Force on Neonatal Encephalopathy and Cerebral Palsy.
  
  
  METHODS
  In this descriptive study, patients in the case group were obtained from a registry of singleton, liveborn, term, neurologically impaired neonates. Entry criteria included a reactive intrapartum fetal heart rate pattern followed by a sudden, rapid, and sustained deterioration of the fetal heart rate that lasted until delivery and an umbilical artery cord pH. All patients in the case group were then assessed to determine if they met the criteria developed by the Task Force on Neonatal Encephalopathy and Cerebral Palsy.
  
  
  RESULTS
  Thirty-nine neonates met the entry criteria, and the proportion meeting each essential criterion was as follows: 38 of 39 (97.4%) had umbilical artery pH of less than 7.00 and 30 of 30 (100%) had a base deficit of 12 mmol/L or higher; 33 of 34 (97%) had either moderate or severe encephalopathy; 34 of 36 (94%) had spastic quadriplegia or dyskinetic cerebral palsy or death attributable to brain injury; and 39 of 39 (100%) had no identifiable reason for exclusion.
  
  
  CONCLUSIONS
  Fetuses that underwent a sudden and sustained deterioration of the fetal heart rate and that subsequently were found to have cerebral palsy demonstrated characteristics consistent with criteria developed by the Task Force on Neonatal Encephalopathy and Cerebral Palsy for intrapartum asphyxial injury.
  
  
  METHODS
  III.
authors.affiliation: Department of Obstetrics and Gynecology, Citrus Valley Medical Center, West Covina, CA, USA. phelanjp@earthlink.net
authors.forename: Jeffrey P
authors.initials: JP
authors.lastname: Phelan
authors.forename: Lisa Marie
authors.initials: LM
authors.lastname: Korst
authors.forename: Gilbert I
authors.initials: GI
authors.lastname: Martin
mesh_terms: D000328:Adult; D001238:Asphyxia Neonatorum / Q000145:classification / Q000150:complications* / Q000175:diagnosis*; D002547:Cerebral Palsy / Q000097:blood / Q000209:etiology*; D005260:Female; D005312:Fetal Blood / Q000737:chemistry; D006340:Heart Rate, Fetal; D006801:Humans; D006863:Hydrogen-Ion Concentration; D020925:Hypoxia-Ischemia, Brain / Q000150:complications* / Q000503:physiopathology; D007231:Infant, Newborn; D008297:Male; D017410:Practice Guidelines as Topic; D011247:Pregnancy; D012720:Severity of Illness Index; D014469:Umbilical Arteries / Q000503:physiopathology; D055815:Young Adult