title: A short synthesis of bisabolane sesquiterpenes.
abstract: A facile total synthesis of three members of the bisabolane sesquiterpene family, namely (±)-curcumene, (±)-xanthorrhizol and (±)-curcuhydroquinone had been achieved in high overall yield. The synthesis used bromobenzene derivatives as starting materials. The halogen-lithium exchange followed by addition of isoprenylacetone and reduction of the obtained carbinols are the key steps of the synthetic pathway. This synthetic approach provides a new route to the bisabolane sesquiterpenes.
authors.affiliation: College of Science, Northwest A&F University, Yangling, Shaanxi 712100, China. duzt@nwsuaf.edu.cn
authors.forename: Zhen-Ting
authors.initials: ZT
authors.lastname: Du
authors.forename: Shuai
authors.initials: S
authors.lastname: Zheng
authors.forename: Gang
authors.initials: G
authors.lastname: Chen
authors.forename: Dong
authors.initials: D
authors.lastname: Lv
mesh_terms: D001969:Bromobenzenes / Q000737:chemistry; D010636:Phenols / Q000138:chemical synthesis* / Q000737:chemistry; D012717:Sesquiterpenes / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D001969:Bromobenzenes; D010636:Phenols; D012717:Sesquiterpenes; C568729:curcuhydroquinone; C120248:xanthorrhizol; C086829:alpha-curcumene