title: Ginkgo biloba extract alters the binding of the sodium [123I] iodide (Na123I) on blood constituents.
abstract: We evaluated the in vitro effect of an aqueous extract of Ginkgo biloba (EGb) on the distribution in blood cells (BC) and plasma (P) and on the binding of Na(123)I to the blood constituents using precipitation with trichloroacetic acid. The radioactivity percentages insoluble (SF) and insoluble fraction (IF) of blood constituents were determined. The EGb interfered (p<0.05) on the distribution of Na(123)I in the P (from 69.64 to 86.13) and BC (from 30.36 to 13.87) and altered the fixation of the Na(123)I in IF-P and in IF-BC.
authors.affiliation: Universidade do Estado do Rio de Janeiro, Instituto de Biologia Roberto Alcântara Gomes, Departamento de Biofísica e Biometria, 28 de Setembro, 87, 20551-030, Rio de Janeiro, RJ, Brasil.
authors.forename: Luiz Cláudio Martins
authors.initials: LC
authors.lastname: Aleixo
authors.forename: Silvana Ramos Farias
authors.initials: SR
authors.lastname: Moreno
authors.forename: Rosimeire de Souza
authors.initials: Rde S
authors.lastname: Freitas
authors.forename: Hélio
authors.initials: H
authors.lastname: Thomaz
authors.forename: Sebastião David
authors.initials: SD
authors.lastname: Santos-Filho
authors.forename: Mario
authors.initials: M
authors.lastname: Bernardo-Filho
mesh_terms: D001774:Blood Chemical Analysis / Q000379:methods*; D001798:Blood Proteins / Q000737:chemistry*; D020441:Ginkgo biloba / Q000737:chemistry*; D006801:Humans; D007457:Iodine Radioisotopes / Q000737:chemistry; D010936:Plant Extracts / Q000737:chemistry*; D011485:Protein Binding; D025941:Protein Interaction Mapping / Q000379:methods*; D012974:Sodium Iodide / Q000737:chemistry*
chemical_list: D001798:Blood Proteins; D007457:Iodine Radioisotopes; D010936:Plant Extracts; D012974:Sodium Iodide