title: [Hirschsprung's disease in adults].
abstract: Up-to-date information about Hirschsprung's disease in children and adults is presented including definition of this pathology, data on its prevalence, and debatable questions of terminology. Etiology and pathogenesis of Hirschsprung"s disease, the role of hereditary factors in its development and clinico-anatomic classification are considered. Clinical variants of Hirschsprung's disease in children and adults are discussed along with its complications and combinations with other congenital malformations. Diagnostic and informative value of clinical and instrumental tools is assessed. Modern methods of conservative and surgical treatment are described.
authors.forename: Ia S
authors.initials: IaS
authors.lastname: Tsimmerman
mesh_terms: D000328:Adult; D002648:Child; D006627:Hirschsprung Disease / Q000145:classification / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D006801:Humans