title: Visual involvement in corticobasal syndrome.
abstract: Corticobasal syndrome (CBS) is the clinical presentation of corticobasal degeneration (CBD), a rare neurodegenerative disorder, with features of both cerebral and basal ganglia involvement. Visual disturbance is uncommonly a predominant symptom but when present can be markedly debilitating. Visual findings primarily manifest as oculomotor apraxia, but significant cognitive impairment may result in the inability to process visuospatial information and can result in simultagnosia and visuomotor ataxia. A 60-year-old woman with a history of CBS presented with progressive visual impairment. Her symptoms were primarily due to severe oculomotor apraxia, optic ataxia, and pronounced simultagnosia. We present the case and review the literature regarding visual dysfunction in CBS.
authors.affiliation: Department of Ophthalmology and Visual Sciences, Washington University, Saint Louis, Missouri 63110, USA.
authors.forename: Rithwick
authors.initials: R
authors.lastname: Rajagopal
authors.forename: Randall
authors.initials: R
authors.lastname: Bateman
authors.forename: Gregory P
authors.initials: GP
authors.lastname: Van Stavern
mesh_terms: D001479:Basal Ganglia / Q000473:pathology*; D002540:Cerebral Cortex / Q000473:pathology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D019636:Neurodegenerative Diseases / Q000150:complications* / Q000473:pathology; D014786:Vision Disorders / Q000209:etiology*