title: Composition of Satureja kitaibelii essential oil and its antimicrobial activity.
abstract: The composition of the essential oil obtained by hydrodistillation from the aerial parts of Satureja kitaibelii from Rtanj mountain (Serbia), collected during three years, was studied. Thirty-nine components were identified in each sample of S. kitaibelii essential oil, representing about 87% of the oils. p-Cymene was the most dominant compound in all three oils (27.9%, 14.7% and 24.4%, respectively). The simple formulation of a lozenge with 0.2% of S. kitaibelii essential oil was prepared and the antimicrobial activity of the essential oil and the lozenge with essential oil was tested using a broth microdilution assay. Both essential oil and lozenge possessed strong antimicrobial activity with MIC values of 0.10-25 microg/mL, and 0.97-15.6 mg/mL, respectively.
authors.affiliation: Department of Pharmacognosy, Faculty of Pharmacy, University of Belgrade, Vojvode Stepe 450, 11221 Belgrade, Serbia. ktatjana@pharmacy.bg.ac.rs
authors.forename: Tatjana
authors.initials: T
authors.lastname: Kundaković
authors.forename: Marina
authors.initials: M
authors.lastname: Milenković
authors.forename: Sasa
authors.initials: S
authors.lastname: Zlatković
authors.forename: Nada
authors.initials: N
authors.lastname: Kovacević
authors.forename: Nikolić
authors.initials: N
authors.lastname: Goran
mesh_terms: D000890:Anti-Infective Agents / Q000737:chemistry / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects; D009822:Oils, Volatile / Q000737:chemistry* / Q000494:pharmacology*; D018515:Plant Leaves / Q000737:chemistry; D010938:Plant Oils / Q000737:chemistry* / Q000494:pharmacology*; D031362:Satureja / Q000737:chemistry*
chemical_list: D000890:Anti-Infective Agents; D009822:Oils, Volatile; D010938:Plant Oils