title: High-throughput GC/MS and HPLC/MS/MS techniques for the multiclass, multiresidue determination of 653 pesticides and chemical pollutants in tea.
abstract: An efficient and sensitive method has been established for simultaneous determination of 653 pesticides in teas by GC/MS and HPLC/MS/MS. The method involved extraction with acetonitrile followed by cleanup using Cleanert-TPT SPE and subsequent identification and quantitation of 490 pesticides by GC/MS and 448 pesticides by HPLC/MS/ MS. The LODs for pesticides determined by GC/MS were between 1.0 and 500 microg/kg, and those determined by HPLC/MS/MS were between 0.03 and 4820 microg/kg. At the low fortification levels of 0.01-100 microg/kg, the average recoveries of 94% of the pesticides determined by GC/MS were between 60 and 120%, 77% of which had an RSD below 20%. For 91% of pesticides determined by HPLC/MS/MS, the average recoveries were between 60 and 120%, 76% of which had an RSD below 20%. The paper also reports a novel SPE column, Cleanert TPT, which comprised graphitized carbon black (PestiCarb), polyamine silica, and amide polystyrene for purifying the tea samples. The results indicated good repeatiblity and reproducibility.
authors.affiliation: Chinese Academy of Inspection and Quarantine, No. 3 Gaobeidian North Rd 100123, Chaoyang District, Beijing, People's Republic of China. qhdciqgfpang@yahoo.com.cn
authors.forename: Guo-Fang
authors.initials: GF
authors.lastname: Pang
authors.forename: Chun-Lin
authors.initials: CL
authors.lastname: Fan
authors.forename: Feng
authors.initials: F
authors.lastname: Zhang
authors.forename: Yan
authors.initials: Y
authors.lastname: Li
authors.forename: Qiao-Ying
authors.initials: QY
authors.lastname: Chang
authors.forename: Yan-Zhong
authors.initials: YZ
authors.lastname: Cao
authors.forename: Yong-Ming
authors.initials: YM
authors.lastname: Liu
authors.forename: Zeng-Yin
authors.initials: ZY
authors.lastname: Li
authors.forename: Qun-Jie
authors.initials: QJ
authors.lastname: Wang
authors.forename: Xue-Yan
authors.initials: XY
authors.lastname: Hu
authors.forename: Ping
authors.initials: P
authors.lastname: Liang
mesh_terms: D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D004785:Environmental Pollutants / Q000737:chemistry*; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods*; D010573:Pesticide Residues / Q000737:chemistry*; D010575:Pesticides / Q000737:chemistry*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D053719:Tandem Mass Spectrometry / Q000379:methods*; D013662:Tea / Q000737:chemistry*
chemical_list: D004785:Environmental Pollutants; D010573:Pesticide Residues; D010575:Pesticides; D013662:Tea