title: Functional neuroimaging of the reciprocal influences between sleep and wakefulness.
abstract: The activity patterns adopted by brain neuronal populations differ dramatically between wakefulness and sleep. However, these vigilance states are not independent and they reciprocally interact. Here, we provide evidence that in humans, regional brain activity during wakefulness is influenced by sleep regulation, namely by the interaction between sleep homeostasis and circadian signals. We also show that, by contrast, regional brain activity during sleep is influenced by the experience acquired during the preceding waking period. These data reveal the dynamic interactions by which the succession of vigilance states support normal brain function and human cognition.
authors.affiliation: Cyclotron Research Centre (B30), University of Liège, 6, Allée du 8 Août, 4000, Liège, Belgium.
authors.forename: Zayd
authors.initials: Z
authors.lastname: Jedidi
authors.forename: Estelle
authors.initials: E
authors.lastname: Rikir
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Muto
authors.forename: Laura
authors.initials: L
authors.lastname: Mascetti
authors.forename: Caroline
authors.initials: C
authors.lastname: Kussé
authors.forename: Ariane
authors.initials: A
authors.lastname: Foret
authors.forename: Anahita
authors.initials: A
authors.lastname: Shaffii-Le Bourdiec
authors.forename: Gilles
authors.initials: G
authors.lastname: Vandewalle
authors.forename: Pierre
authors.initials: P
authors.lastname: Maquet
mesh_terms: D001921:Brain / Q000502:physiology*; D057906:Circadian Clocks / Q000502:physiology; D059907:Functional Neuroimaging; D006706:Homeostasis / Q000502:physiology; D006801:Humans; D012890:Sleep / Q000502:physiology*; D014851:Wakefulness / Q000502:physiology*