title: Physicochemical properties, in vitro antioxidant activities and inhibitory potential against α-glucosidase of polysaccharides from Ampelopsis grossedentata leaves and stems.
abstract: In the present study, polysaccharides named ALPS and ASPS were isolated from Ampelopsis grossedentata leaves and stems, respectively. Physicochemical properties, in vitro antioxidant activities and the inhibitory effects on α-glucosidase of ALPS and ASPS were investigated. It was found that both ALPS and ASPS were acid protein-bound heteropolysaccharides, although with considerably different chemical composition and molecular weight distribution. Meanwhile, in comparison with ALPS, ASPS exhibited stronger antioxidant activity and inhibitory potential against α-glucosidase according to the in vitro evaluation. Moreover, our results suggested that protein and uronic acid might, at least partly, contribute positively to the biological behavior of ALPS and ASPS.
authors.affiliation: Department of Tea Science, Zhejiang University, Hangzhou 310058, China.
authors.forename: Yuefei
authors.initials: Y
authors.lastname: Wang
authors.forename: Xiaoying
authors.initials: X
authors.lastname: Bian
authors.forename: Jinhyouch
authors.initials: J
authors.lastname: Park
authors.forename: Le
authors.initials: L
authors.lastname: Ying
authors.forename: Lisheng
authors.initials: L
authors.lastname: Qian
authors.forename: Ping
authors.initials: P
authors.lastname: Xu
mesh_terms: D032421:Ampelopsis / Q000737:chemistry*; D052160:Benzothiazoles / Q000737:chemistry; D001713:Biphenyl Compounds / Q000737:chemistry; D002614:Chelating Agents / Q000737:chemistry; D057075:Enzyme Assays; D005296:Ferrous Compounds / Q000737:chemistry; D016166:Free Radical Scavengers / Q000737:chemistry*; D065089:Glycoside Hydrolase Inhibitors; D010851:Picrates / Q000737:chemistry; D010936:Plant Extracts / Q000737:chemistry*; D018515:Plant Leaves / Q000737:chemistry*; D010940:Plant Proteins / Q000737:chemistry; D018547:Plant Stems / Q000737:chemistry*; D011134:Polysaccharides / Q000737:chemistry*; D011509:Proteoglycans / Q000737:chemistry; D013451:Sulfonic Acids / Q000737:chemistry; D000520:alpha-Glucosidases / Q000737:chemistry
chemical_list: D052160:Benzothiazoles; D001713:Biphenyl Compounds; D002614:Chelating Agents; D005296:Ferrous Compounds; D016166:Free Radical Scavengers; D065089:Glycoside Hydrolase Inhibitors; D010851:Picrates; D010936:Plant Extracts; D010940:Plant Proteins; D011134:Polysaccharides; D011509:Proteoglycans; D013451:Sulfonic Acids; C002502:2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid; C020748:ferrous sulfate; C004931:1,1-diphenyl-2-picrylhydrazyl; D000520:alpha-Glucosidases