title: [Tako-Tsubo syndrome during normal human immunoglobolin perfusion].
abstract: This is a case of an 82 year old female patient with myasthenia gravis, who following treatment with Human Normal Immunoglobulin (Tegeline(®)), developed dyspnoea, chest pain without cardiac insufficiency, inverted T wave on ECG with slight increase in Troponine T 0.43ng/mL (<0.2ng/mL normal value in our hospital) and marked increase in Pro-BNP 4900 (Nl≤450pg/mL for an age greater than 65 years old). Her coronary angiogram showed hypokinesia of apical area but was otherwise normal. Also, MRI ruled out inflammatory and ischemic cardiac diseases. The most likely diagnosis for us was Tako-Tsubo syndrome in relation with injection of Human Normal Immunoglobulin (Tegeline(®)) according to the Mayo clinic criteria.
authors.affiliation: Unité de réanimation polyvalente et soins intensifs cardiaques, médecine interne et cardiologie, centre hospitalier Jacques-Lacarin, Vichy, France.
authors.forename: P
authors.initials: P
authors.lastname: Gautier
authors.forename: R
authors.initials: R
authors.lastname: Ravan
authors.forename: M
authors.initials: M
authors.lastname: Najjar
authors.forename: A
authors.initials: A
authors.lastname: Belhakem
authors.forename: N
authors.initials: N
authors.lastname: Ferrier
authors.forename: X
authors.initials: X
authors.lastname: Marcaggi
authors.forename: R
authors.initials: R
authors.lastname: Colamarino
authors.forename: G
authors.initials: G
authors.lastname: Amat
mesh_terms: D000369:Aged, 80 and over; D015415:Biomarkers / Q000097:blood; D003937:Diagnosis, Differential; D004562:Electrocardiography; D005260:Female; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000008:administration & dosage / Q000009:adverse effects*; D007155:Immunologic Factors / Q000008:administration & dosage / Q000009:adverse effects*; D008279:Magnetic Resonance Imaging; D009157:Myasthenia Gravis / Q000188:drug therapy; D045283:Natriuretic Agents / Q000097:blood; D020097:Natriuretic Peptide, Brain / Q000097:blood; D054549:Takotsubo Cardiomyopathy / Q000097:blood / Q000139:chemically induced* / Q000175:diagnosis*; D020107:Troponin T / Q000097:blood
chemical_list: D015415:Biomarkers; D016756:Immunoglobulins, Intravenous; D007155:Immunologic Factors; D045283:Natriuretic Agents; D020107:Troponin T; D020097:Natriuretic Peptide, Brain