title: [Three cases effectively treated with S-1 therapy for liver metastasis of breast cancer in long term].
abstract: We experienced 3 cases of anti-cancer drug-resistant recurrent breast cancer with liver metastasis showing significant improvement by S-1. Almost all patients maintained the full dose through the whole course of treatment, and the drug showed good tolerability. Furthermore, long-term therapeutic efficacy(more than 2 years)and QOL have been maintained for all patients. We concluded that S-1 is not only effective as a therapeutic agent, but is safe and maintains QOL.
authors.affiliation: Dept. of Surgery, Kishiwada City Hospital.
authors.forename: Tomohiko
authors.initials: T
authors.lastname: Mori
authors.forename: Goro
authors.initials: G
authors.lastname: Yoshimura
authors.forename: Daisuke
authors.initials: D
authors.lastname: Ito
authors.forename: Katsuyoshi
authors.initials: K
authors.lastname: Furumoto
authors.forename: Masafumi
authors.initials: M
authors.lastname: Kogire
mesh_terms: D000368:Aged; D000964:Antimetabolites, Antineoplastic / Q000627:therapeutic use*; D001943:Breast Neoplasms / Q000188:drug therapy* / Q000473:pathology; D004338:Drug Combinations; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000556:secondary; D010094:Oxonic Acid / Q000627:therapeutic use*; D011788:Quality of Life; D005641:Tegafur / Q000627:therapeutic use*; D013997:Time Factors
chemical_list: D000964:Antimetabolites, Antineoplastic; D004338:Drug Combinations; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid