title: Short-term outcome for term and near-term singleton infants with intrapartum polyhydramnios.
abstract: OBJECTIVE
  To evaluate rates of early short-term neonatal complications among term and near-term newborn infants with polyhydramnios.
  
  
  METHODS
  Retrospective data were collected on 788 term infants with prenatal diagnosis of polyhydramnios and 1,576 matched controls, including information on maternal condition and on infant perinatal complications.
  
  
  RESULTS
  The total rate of major congenital malformations among infants born to mothers with polyhydramnios was 2.3% compared to 0.13% for those with normal amniotic fluid index (p < 0.001). Infants in the study group were more likely to be born to diabetic mothers, were heavier and large for gestational age and were more likely to be delivered by cesarean section. Infants with polyhydramnios, but no major congenital malformations, are at increased risk for minor congenital malformations (4.2%) as well as for postnatal complications, such as respiratory distress (5.7%), cardiovascular manifestations (mainly delayed closure of the ductus arteriosus; 3.1%) and hypoglycemia (7%) compared to controls. Multivariate logistic regression revealed that polyhydramnios was associated only with postnatal respiratory distress and hypoglycemia. The severity of polyhydramnios was not associated with an increased rate of neonatal complications.
  
  
  CONCLUSIONS
  Although infants with polyhydramnios, but no major congenital malformations, were found to have increased rates of respiratory distress and hypoglycemia, these clinical manifestations were mild and had little effect on the babies' well-being and length of hospital stay.
authors.affiliation: Department of Neonatology, The Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, Israel.
authors.forename: Leah
authors.initials: L
authors.lastname: Leibovitch
authors.forename: Irit
authors.initials: I
authors.lastname: Schushan-Eisen
authors.forename: Jacob
authors.initials: J
authors.lastname: Kuint
authors.forename: Alina
authors.initials: A
authors.lastname: Weissmann-Brenner
authors.forename: Ayala
authors.initials: A
authors.lastname: Maayan-Metzger
mesh_terms: D000328:Adult; D015897:Comorbidity; D000013:Congenital Abnormalities / Q000175:diagnosis / Q000453:epidemiology*; D005260:Female; D005865:Gestational Age; D006801:Humans; D007003:Hypoglycemia / Q000175:diagnosis / Q000453:epidemiology; D007231:Infant, Newborn; D007234:Infant, Premature; D007557:Israel / Q000453:epidemiology; D008297:Male; D006831:Polyhydramnios / Q000175:diagnosis / Q000453:epidemiology*; D011247:Pregnancy; D012127:Respiratory Distress Syndrome, Newborn / Q000175:diagnosis / Q000453:epidemiology; D012189:Retrospective Studies; D015996:Survival Rate; D047929:Term Birth