title: [Study of gly-proline-containing peptides (PGP and GPGPGP) degradation by aggressive factors in vitro].
abstract: PGP, as well as GPGPGP remain stable after 24-hour incubation in a proteolytic environment (in vitro), like equine and rat gastric juice, hydrochloric acid and pepsin in the solution of hydrochloric acid. Perhaps the appearance of PGP's metabolites--PG and GP, that found in the stomachic tissues, is associated with the action of tissue and blood peptidases. Thus, the effects of PGP and GPGPGP cause by the influences both of the peptides and their metabolites, that agree with previously results.
authors.forename: A V
authors.initials: AV
authors.lastname: Trufanova
authors.forename: G E
authors.initials: GE
authors.lastname: Samonina
authors.forename: Iu A
authors.initials: IuA
authors.lastname: Zolotarev
authors.forename: K V
authors.initials: KV
authors.lastname: Shevchenko
mesh_terms: D000818:Animals; D004305:Dose-Response Relationship, Drug; D004355:Drug Stability; D005750:Gastric Juice / Q000737:chemistry*; D005998:Glycine / Q000031:analogs & derivatives* / Q000737:chemistry; D006736:Horses; D066298:In Vitro Techniques; D008297:Male; D009842:Oligopeptides / Q000737:chemistry*; D011392:Proline / Q000031:analogs & derivatives* / Q000737:chemistry; D051381:Rats
chemical_list: C561661:GPGPGP peptide; D009842:Oligopeptides; C113164:prolyl-glycyl-proline; D011392:Proline; D005998:Glycine