title: Chronic kidney disease in urolithiasis patients following successful             extracorporeal shockwave lithotripsy.
abstract: Recently, it has been reported that kidney stones are a significant and             independent risk factor for chronic kidney disease (CKD) in the general population.             However, the prevalence of CKD in patients following successful extracorporeal             shockwave lithotripsy (ESWL) has yet to be elucidated. In the present study, the             prevalence of CKD and the clinical factors associated with the presence of CKD             in patients following successful ESWL were investigated. A cross‑sectional study             was performed in 114 patients who had undergone ESWL for upper urinary tract stones             and 96 age- and gender-matched healthy control subjects. We initially determined             the stage of CKD and compared the prevalence of CKD between healthy subjects and             patients who underwent successful ESWL. We then investigated the clinical factors             associated with the presence of CKD by logistic regression analysis. The prevalence             of CKD was significantly higher in patients following successful ESWL than in             the healthy subjects [40 patients (35.1%) vs. 9 healthy controls (9.4%), P<0.0001].             Logistic regression analysis showed that the significant factors associated with             the presence of CKD were increased body mass index (BMI) and the presence of a             ureteric stone (pre‑ESWL stone position). The findings indicated that there was             a high prevalence of CKD among patients following successful ESWL, and that an             increased BMI and a ureteric stone were factors associated with the presence of             CKD.
authors.affiliation: Department of Urology, Osaka City University Graduate School of Medicine, Osaka, Japan.
authors.forename: Satoshi
authors.initials: S
authors.lastname: Maeda
authors.forename: Toshihide
authors.initials: T
authors.lastname: Naganuma
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Takemoto
authors.forename: Tetsuo
authors.initials: T
authors.lastname: Shoji
authors.forename: Mikio
authors.initials: M
authors.lastname: Okamura
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Nakatani
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D015992:Body Mass Index; D002908:Chronic Disease; D003404:Creatinine / Q000097:blood; D003430:Cross-Sectional Studies; D005260:Female; D005919:Glomerular Filtration Rate; D006801:Humans; D006973:Hypertension / Q000150:complications; D007674:Kidney Diseases / Q000150:complications* / Q000453:epidemiology*; D008096:Lithotripsy / Q000706:statistics & numerical data*; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D015995:Prevalence; D012307:Risk Factors; D012737:Sex Factors; D052878:Urolithiasis / Q000150:complications* / Q000628:therapy*
chemical_list: D003404:Creatinine