title: [Clinical features and experience of diagnosis and treatment of thyroid neoplasm in children].
abstract: OBJECTIVE
  To study the clinical features, diagnosis and therapy of thyroid neoplasm in children.
  
  
  METHODS
  A retrospective study was performed on 32 children with thyroid nodular who were underwent operation in Xiangya Hospital between January 2002 and December 2010.
  
  
  RESULTS
  Of the 32 cases, there were 23 girls and 9 boys. Six cases were diagnosed as nodular Goiter adenoma and 26 cases were diagnosed as thyroid papillary carcinoma. B-ultrasonic examination showed a 100% accurate rate for the diagnosis of thyroid carcinoma. Fourteen children (44%) were proven to have concurrent Hashimoto's thyroiditis. Twenty-two (69%) children with thyroid carcinoma were found to have lymph metastasis in the lateral neck. The children younger than 10 years showed a high rate of metastasis than those older one (94% vs 56%, P<0.05). All 32 children received a surgical therapy. Subtotal thyroidectomy was performed on the 6 children with nodular Goiter adenoma. Total thyroidectomy (17 cases) or ipsilateral thyroidectomy (9 cases) was performed according to the stage of thyroid carcinoma. The surgical outcomes were followed up for 3 months to 9 years and no recurrence or death occurred. The development and growth were normal in the children.
  
  
  CONCLUSIONS
  Childhood thyroid nodular attacks girls more than boys, and the frequency of malignancy is high. Hashimoto's thyroiditis is a common concurrent disease. The incidence of local lymph metastasis is high in those younger than 10 years. The surgical therapy for thyroid neoplasm may lead satisfactory outcomes in children.
authors.affiliation: Department of General Surgery, Xiangya Hospital of Central South University, Changsha, China.
authors.forename: Shi
authors.initials: S
authors.lastname: Chang
authors.forename: Zhen-Han
authors.initials: ZH
authors.lastname: Deng
authors.forename: Chao
authors.initials: C
authors.lastname: Dong
authors.forename: Zhi-Peng
authors.initials: ZP
authors.lastname: Zhang
authors.forename: Hui-Jun
authors.initials: HJ
authors.lastname: Liao
authors.forename: Zhi-Ming
authors.initials: ZM
authors.lastname: Wang
mesh_terms: D000293:Adolescent; D002648:Child; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D012189:Retrospective Studies; D013964:Thyroid Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery*