title: Analysis and antimicrobial activity of volatile constituents from Quercus leucotrichophora (Fagaceae) bark.
abstract: The chemical composition of the volatile extract (yield ≈ 0.13%, v/w) from the bark of Quercus leucotrichophora (Fagaceae) was analysed for the first time by GC-MS. Twenty-three constituents, amounting to 93.0% of the total detected contents of the volatile extract, were identified. The volatile extract contained approximately 86.36% monoterpenoids, 6.53% sesquiterpenoids and 0.11% aliphatic aldehydes. 1,8-Cineol (40.359%) followed by γ-terpinene (16.369%) were the major monoterpene constituents of the volatile extract. The residue of volatile extract (0.00025-250 µg  mL(-1)) exhibited a potent antimicrobial activity against Streptococcus pyogenes ATCC 19615. This study concludes that residues of the volatile extract of Q. leucotrichophora could serve as an important bioresource for the extraction and isolation of monoterpenoids exhibiting antimicrobial activity, and thus has good potential for use in the pharmaceutical industry.
authors.affiliation: Department of Chemistry, HNB Garhwal University, Srinagar, Garhwal, Uttarakhand, India. sushilsati1983@gmail.com
authors.forename: Sushil Chandra
authors.initials: SC
authors.lastname: Sati
authors.forename: Nitin
authors.initials: N
authors.lastname: Sati
authors.forename: O P
authors.initials: OP
authors.lastname: Sati
authors.forename: D
authors.initials: D
authors.lastname: Biswas
authors.forename: B S
authors.initials: BS
authors.lastname: Chauhan
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology; D000890:Anti-Infective Agents / Q000032:analysis*; D008826:Microbial Sensitivity Tests; D024301:Plant Bark / Q000737:chemistry*; D029963:Quercus / Q000737:chemistry*; D013297:Streptococcus pyogenes / Q000187:drug effects; D014835:Volatilization
chemical_list: D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents