title: Reactive oxygen species as transducers of sphinganine-mediated cell death pathway.
abstract: Long chain bases or sphingoid bases are building blocks of complex sphingolipids that display a signaling role in programmed cell death in plants. So far, the type of programmed cell death in which these signaling lipids have been demonstrated to participate is the cell death that occurs in plant immunity, known as the hypersensitive response. The few links that have been described in this pathway are: MPK6 activation, increased calcium concentrations, and reactive oxygen species (ROS) generation. The latter constitute one of the more elusive loops because of the chemical nature of ROS the multiple possible cell sites where they can be formed and the ways in which they influence cell structure and function.
authors.affiliation: Departamento de Bioquímica, Fac. de Química, Universidad Nacional Autónoma de México, México, D.F. México.
authors.forename: Mariana
authors.initials: M
authors.lastname: Saucedo-García
authors.forename: Ariadna
authors.initials: A
authors.lastname: González-Solís
authors.forename: Priscila
authors.initials: P
authors.lastname: Rodríguez-Mejía
authors.forename: Teresa de Jesús
authors.initials: Tde J
authors.lastname: Olivera-Flores
authors.forename: Sonia
authors.initials: S
authors.lastname: Vázquez-Santana
authors.forename: Edgar B
authors.initials: EB
authors.lastname: Cahoon
authors.forename: Marina
authors.initials: M
authors.lastname: Gavilanes-Ruiz
mesh_terms: D017360:Arabidopsis / Q000166:cytology* / Q000187:drug effects / Q000378:metabolism* / Q000648:ultrastructure; D016923:Cell Death / Q000187:drug effects; D002736:Chloroplasts / Q000187:drug effects / Q000378:metabolism / Q000648:ultrastructure; D037341:Fumonisins / Q000494:pharmacology; D006861:Hydrogen Peroxide / Q000378:metabolism; D008928:Mitochondria / Q000187:drug effects / Q000648:ultrastructure; D017382:Reactive Oxygen Species / Q000378:metabolism*; D015398:Signal Transduction / Q000187:drug effects*; D013110:Sphingosine / Q000031:analogs & derivatives* / Q000494:pharmacology
chemical_list: D037341:Fumonisins; D017382:Reactive Oxygen Species; C056933:fumonisin B1; D006861:Hydrogen Peroxide; D013110:Sphingosine; C005682:safingol