title: Diagnosis and prognosis of malignant mesothelioma of the tunica vaginalis testis.
abstract: OBJECTIVE
  The objective of this study is to evaluate the diagnosis and prognosis of malignant mesothelioma of the tunica vaginalis testis through an additional 6 patients with urogenital mesothelioma.
  
  
  METHODS
  Six patients with urogenital mesothelioma who underwent adequate surgical procedures and histopathologic analysis from 1990 to 2009 were identified and retrospectively reviewed.
  
  
  RESULTS
  Six patients between the ages of 26 and 78 years with urogenital mesothelioma, 5 of which originated in the scrotum and 1 in the spermatic cord. Histopathologic analysis showed that CK5/6 and calretinin were positive in all cases, 5 cases were positive for vimentin, and 1 case showed focal weak positive reaction with MOC3, but none of the cases stained for CEA or CD15. The overall recurrence rate of urogenital mesothelioma after surgery was 5/6, including local recurrences and fatalities due to tumour.
  
  
  CONCLUSIONS
  In cases of mesothelioma of the tunica vaginalis testis, the histopathologic markers we chose helped confirm the histopathological diagnosis; adequate surgical procedures are typically not curative, and this tumour is often fatal.
authors.affiliation: Department of Urology, Union Hospital, Tongji Medical School, Huazhong University of Science and Technology, Wuhan, China;
authors.forename: Bo
authors.initials: B
authors.lastname: Hai
authors.forename: Yu
authors.initials: Y
authors.lastname: Yang
authors.forename: Yajun
authors.initials: Y
authors.lastname: Xiao
authors.forename: Bing
authors.initials: B
authors.lastname: Li
authors.forename: Chaohui
authors.initials: C
authors.lastname: Chen