title: A hospital-wide quality-improvement collaborative to reduce catheter-associated bloodstream infections.
abstract: BACKGROUND
  Catheter-associated bloodstream infections (CA BSIs) are associated with increased hospital length of stay, total hospital costs, and mortality. Quality-improvement collaboratives (QICs) are frequently used to improve health care quality. Our PICU was previously involved in a successful national QIC to reduce the incidence of CA BSI in critically ill children.
  
  
  OBJECTIVE
  We hypothesized that the formation of a hospital-wide QIC would reduce the incidence of CA BSI throughout our institution.
  
  
  METHODS
  We retrospectively reviewed the incidence of CA BSI from March 2006 to March 2010. The collaborative approach included hospital-wide implementation of central-line insertion and maintenance bundles that emphasized full sterile barrier precautions and chlorhexidine skin preparation during line insertion, daily discussion of catheter necessity, and meticulous site and tubing care. The hospital units involved were our 3 critical care units, the oncology unit, the bone marrow transplant unit, and wards. Each individual unit was responsible for collecting unit-specific data and performing event-cause analysis within 48 hours of identifying a CA BSI. These results were shared with the other hospital units during monthly meetings. Compliance with the insertion and maintenance bundles was monitored and reported to each unit monthly.
  
  
  RESULTS
  The hospital-wide CA-BSI rate decreased from a baseline of 3.0 to <1.0 CA BSI per 1000 line-days after implementation of the QIC.
  
  
  CONCLUSIONS
  Our hospital-wide QIC resulted in a significant reduction in the incidence of CA BSI at our children's hospital. A collaborative model based on improvement science methodology is both feasible and effective in reducing the incidence of CA BSI.
authors.affiliation: Division of Critical Care Medicine, Cincinnati Children's Hospital Medical Center,Cincinnati, Ohio 45229-3039, USA. derek.wheeler@cchmc.org
authors.forename: Derek S
authors.initials: DS
authors.lastname: Wheeler
authors.forename: Mary Jo
authors.initials: MJ
authors.lastname: Giaccone
authors.forename: Nancy
authors.initials: N
authors.lastname: Hutchinson
authors.forename: Mary
authors.initials: M
authors.lastname: Haygood
authors.forename: Pattie
authors.initials: P
authors.lastname: Bondurant
authors.forename: Kathy
authors.initials: K
authors.lastname: Demmel
authors.forename: Uma R
authors.initials: UR
authors.lastname: Kotagal
authors.forename: Beverly
authors.initials: B
authors.lastname: Connelly
authors.forename: Melinda S
authors.initials: MS
authors.lastname: Corcoran
authors.forename: Kristin
authors.initials: K
authors.lastname: Line
authors.forename: Kate
authors.initials: K
authors.lastname: Rich
authors.forename: Pamela J
authors.initials: PJ
authors.lastname: Schoettker
authors.forename: Richard J
authors.initials: RJ
authors.lastname: Brilli
mesh_terms: D016470:Bacteremia / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control*; D055499:Catheter-Related Infections / Q000453:epidemiology / Q000517:prevention & control*; D002405:Catheterization, Central Venous / Q000379:methods / Q000592:standards* / Q000706:statistics & numerical data; D002648:Child; D003299:Cooperative Behavior; D003428:Cross Infection / Q000453:epidemiology / Q000517:prevention & control*; D019983:Guideline Adherence / Q000706:statistics & numerical data; D006776:Hospitals, Pediatric / Q000592:standards*; D006801:Humans; D009820:Ohio; D010043:Outcome and Process Assessment, Health Care; D058996:Quality Improvement / Q000458:organization & administration / Q000706:statistics & numerical data*; D012189:Retrospective Studies