title: Excessive eosinophilia as paraneoplastic syndrome in a patient with non-small-cell lung carcinoma: a case report and review of the literature.
abstract: Hypereosinophilia is a phenomenon which is associated with a broad variety of allergic, infectious, paraneoplastic and systemic diseases. Depending on the aetiology, these disorders differ in severity from self-limiting to life-threatening. Although it is well known that hypereosinophilia can occur in association with a solid tumour, exact numbers of incidence are lacking. We describe a patient with respiratory insufficiency and an elevated level of eosinophils in the peripheral blood. A diagnostic work-up revealed the presence of a disseminated non-small-cell carcinoma of the lung; an association not frequently described.
authors.affiliation: Department of Pulmonary Medicine, Antwerp University Hospital, University of Antwerp, Antwerp, Belgium. An-Sofie.Verstraeten@uza.be
authors.forename: A S
authors.initials: AS
authors.lastname: Verstraeten
authors.forename: A
authors.initials: A
authors.lastname: De Weerdt
authors.forename: G
authors.initials: G
authors.lastname: van Den Eynden
authors.forename: E
authors.initials: E
authors.lastname: Van Marck
authors.forename: A
authors.initials: A
authors.lastname: Snoeckx
authors.forename: P G
authors.initials: PG
authors.lastname: Jorens
mesh_terms: D000368:Aged; D001859:Bone Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary; D002289:Carcinoma, Non-Small-Cell Lung / Q000453:epidemiology* / Q000473:pathology; D015897:Comorbidity; D004802:Eosinophilia / Q000453:epidemiology*; D006801:Humans; D008175:Lung Neoplasms / Q000453:epidemiology* / Q000473:pathology; D008297:Male; D010257:Paraneoplastic Syndromes / Q000453:epidemiology*; D012131:Respiratory Insufficiency / Q000209:etiology; D014057:Tomography, X-Ray Computed