title: Biological properties of sodium alkyl methyl ester sulfonate/alkyltrimethylammonium bromide surfactant mixtures.
abstract: Quaternary ammonium compounds (QACs) are commonly used as disinfectant in medical care, food industry, detergents and glue industries. This is due to a small concentration of QACs is sufficient to inhibit the growth of various bacteria strains. In this work, the inhibitive power of cationic surfactants, alkyltrimethylammonium bromide (C(n)TAB) in the presence of anionic surfactants, sodium alkyl methyl ester α-sulfonate (C(n)MES) was studied. The growth inhibition test with gram-positive (Staphylococcus aureus) and gram-negative (Escherichia coli and Pseudomonas aeruginosa) bacteria were used to determine the toxicity of single and mixed surfactants. Results from this work showed that certain mixed surfactants have lower minimum inhibition concentration (MIC) as compared to the single C(n)TAB surfactants. Besides that, it was also found that alkyl chain length and the mixing ratios of the surfactants play a significant role in determining the mixture inhibitive power.
authors.affiliation: Chemistry Department, Faculty of Science, University of Malaya, Kuala Lumpur, Malaysia.
authors.forename: S P
authors.initials: SP
authors.lastname: Wong
authors.forename: W H
authors.initials: WH
authors.lastname: Lim
authors.forename: S F
authors.initials: SF
authors.lastname: Cheng
authors.forename: C H
authors.initials: CH
authors.lastname: Chuah
mesh_terms: D000476:Alkanesulfonates / Q000737:chemistry* / Q000494:pharmacology; D001965:Bromides / Q000737:chemistry*; D004952:Esters; D006090:Gram-Negative Bacteria / Q000187:drug effects; D006094:Gram-Positive Bacteria / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D000644:Quaternary Ammonium Compounds / Q000737:chemistry* / Q000494:pharmacology; D013501:Surface-Active Agents / Q000737:chemistry* / Q000494:pharmacology
chemical_list: D000476:Alkanesulfonates; D001965:Bromides; D004952:Esters; D000644:Quaternary Ammonium Compounds; D013501:Surface-Active Agents