title: [Study of characteristic of the cochlear hydrops analysis masking procedure in normal adults].
abstract: OBJECTIVE
  To study the characteristic of the cochlear hydrops analysis masking procedure (CHAMP) in normal adults, and to evaluate the diagnostic values of its parameters for membranous labyrinth hydrops.
  
  
  METHODS
  Twenty otologically normal adults were recruited (male:female = 10:10), and their auditory brainstem responses (ABR) were obtained to six stimulus conditions using Bio-logic auditory evoked potential system: clicks presented alone (unmasked condition) and clicks presented with ipsilateral pink noise high-pass filtered at 8, 4, 2, 1, and 0.5 kHz respectively.
  
  
  RESULTS
  The wave V latency of ABR to the high-pass masking pink noise clicks were longer than ABR to clicks alone. The latency delays of wave V for clicks presented with ipsilateral pink noise high-pass filtered at 8, 4, 2, 1, and 0.5 kHz compared to clicks alone were (0.30 ± 0.18), (0.97 ± 0.43), (1.65 ± 0.64), (3.21 ± 0.56), (4.66 ± 0.37) ms respectively. The complex amplitude ratio between ABR to click + 0.5 kHz high-pass noise and click alone was 0.95 ± 0.11.
  
  
  CONCLUSIONS
  CHAMP is a promising diagnostic method for membranous labyrinth hydrops, and the latency delay of wave V might be used as the normal criterion. The specificity of the complex amplitude ratio need further evaluation in clinical work.
authors.affiliation: Department of Otorhinolaryngology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China.
authors.forename: Ying-ying
authors.initials: YY
authors.lastname: Shang
authors.forename: Wen-wen
authors.initials: WW
authors.lastname: Diao
authors.forename: Dao-feng
authors.initials: DF
authors.lastname: Ni
authors.forename: Chun-xiao
authors.initials: CX
authors.lastname: Xu
authors.forename: Zhi-qiang
authors.initials: ZQ
authors.lastname: Gao
authors.forename: Feng-rong
authors.initials: FR
authors.lastname: Li
mesh_terms: D000293:Adolescent; D000328:Adult; D018159:Endolymphatic Hydrops / Q000175:diagnosis* / Q000503:physiopathology; D016057:Evoked Potentials, Auditory, Brain Stem; D005260:Female; D006801:Humans; D008297:Male; D009622:Noise; D010470:Perceptual Masking; D055815:Young Adult