title: Oral propranolol as a new treatment for facial infantile hemangioma: case report.
abstract: Hemangiomas are the most common benign tumors of infancy. Despite their self-limited course, infantile capillary hemangiomas can impair vital or sensory functions as vision and cause cosmetic deformity. The usual treatments include oral/intralesional steroids, alpha interferon, cytotoxins, pulsed dye laser and cosmetic surgery resection. These treatments are not free of multiple complications and toxic side effects. This report describes the case of a 3-month-old female baby with progressively increasing hemangioma of the left upper eyelid impinging over the visual field. The hemangioma promptly responded to low-dose oral propranolol. A clinical response was noticed few days after the beginning of the treatment, with regression to 1/4 of its original size in 45 days of treatment, and to less than 1/10 after 8 months, free of any major side effects.
authors.affiliation: Federal University of São Paulo, São Paulo, SP, Brazil. rosaneferreira@hotmail.com
authors.forename: Rosane da Cruz
authors.initials: Rda C
authors.lastname: Ferreira
authors.forename: Francisco Romeu Locatelli
authors.initials: FR
authors.lastname: Wolff
authors.forename: Ricardo
authors.initials: R
authors.lastname: Mörschbächer
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use*; D005142:Eyelid Neoplasms / Q000188:drug therapy*; D005260:Female; D018324:Hemangioma, Capillary / Q000188:drug therapy*; D006801:Humans; D060828:Induction Chemotherapy / Q000379:methods; D007223:Infant; D009386:Neoplastic Syndromes, Hereditary / Q000188:drug therapy*; D011433:Propranolol / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D000319:Adrenergic beta-Antagonists; D011433:Propranolol