title: Endoscopic management of gastrointestinal stromal tumors.
abstract: Subepithelial lesions are increasingly being identified with improved endoscopic imaging technologies. Many of these lesions are now recognized as gastrointestinal stromal tumors (GISTs). Recent advances in immunohistochemistry have allowed for reliable differentiation of GISTs from other subepithelial tumors, thereby significantly improving our understanding of these lesions. The wealth of recent information and continual evolution in our understanding of GISTs has exposed some knowledge gaps pertaining to the optimal management of these lesions. In this article, we review the endoscopic management of GISTs as it relates to the identification, diagnosis and management of these lesions based on the best available literature and our own clinical experience to date.
authors.affiliation: Hospital of the University of Pennsylvania, GI Division, 3 Ravdin, 3400 Spruce Street, Philadelphia, PA 19104, USA. chandrav@uphs.upenn.edu
authors.forename: Vinay
authors.initials: V
authors.lastname: Chandrasekhara
authors.forename: Gregory G
authors.initials: GG
authors.lastname: Ginsberg
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use; D001706:Biopsy; D016099:Endoscopy, Gastrointestinal; D019160:Endosonography; D005770:Gastrointestinal Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000628:therapy*; D046152:Gastrointestinal Stromal Tumors / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000628:therapy*; D006801:Humans; D018084:Ultrasonography, Interventional
chemical_list: D000970:Antineoplastic Agents