title: Using fluorescence to locate intercalants within the lipid bilayer of liposomes, bioliposomes and erythrocyte ghosts.
abstract: In previous work, we have shown the utility of the "NMR technique" in locating intercalants within the lipid bilayer. We describe herein the development of a more sensitive and complementary "fluorescence technique" for this purpose and its application to liposomes, bioliposomes and erythrocyte ghosts. This technique is based on the observation in selected compounds of an excellent correlation between the emission wavelength (λ(em)) and Dimroth-Reichardt E(T)(30) polarity parameter for the solvent in which the fluorescence emission spectrum was obtained.
authors.affiliation: Department of Chemistry, Bar Ilan University, Ramat Gan, Israel. Michal.Afri@biu.ac.il
authors.forename: Michal
authors.initials: M
authors.lastname: Afri
authors.forename: Miriam E
authors.initials: ME
authors.lastname: Naqqash
authors.forename: Aryeh A
authors.initials: AA
authors.lastname: Frimer
mesh_terms: D002462:Cell Membrane; D004910:Erythrocyte Membrane / Q000737:chemistry; D005453:Fluorescence; D008024:Ligands; D008051:Lipid Bilayers / Q000737:chemistry; D008081:Liposomes / Q000737:chemistry; D008954:Models, Biological; D012997:Solvents
chemical_list: D008024:Ligands; D008051:Lipid Bilayers; D008081:Liposomes; D012997:Solvents