title: Clinical SERS: are we there yet?
abstract: Surface Enhanced Raman Spectroscopy or SERS has witnessed many successes over the past 3 decades, owing particularly to its simplicity of use as well as its highly-multiplexing capability. This article provides an overview of SERS and its applicability in the field of bio-medicine. We will preview recent developments in SERS substrate designs, and the various sensing technologies that are based on the SERS phenomenon. An overview of the clinical applications of SERS is also included. Finally, we provide an opinion on the future trends of this unique spectroscopic technique.
authors.affiliation: Bio-photonics Group, School of Physics, National University of Ireland, Galway, Ireland; National Cancer Centre Singapore, 11 Hospital Drive, Singapore 169610, Singapore.
authors.forename: Kiang Wei
authors.initials: KW
authors.lastname: Kho
authors.forename: Chit Yaw
authors.initials: CY
authors.lastname: Fu
authors.forename: U S
authors.initials: US
authors.lastname: Dinish
authors.forename: Malini
authors.initials: M
authors.lastname: Olivo
mesh_terms: D035843:Biomedical Research / Q000295:instrumentation / Q000379:methods* / Q000639:trends; D006801:Humans; D053758:Nanoparticles; D013059:Spectrum Analysis, Raman / Q000295:instrumentation / Q000379:methods*; D020349:Surface Plasmon Resonance / Q000295:instrumentation / Q000379:methods*; D013499:Surface Properties