title: Comparison of the INNO-LiPA and PapType assays for detection of human papillomavirus in archival vulva dysplasia and/or neoplasia tissue biopsy specimens.
abstract: INNO-LiPA and PapType human papillomavirus (HPV) genotyping assays were compared for detection of HPV genotypes on archival vulvar tissue. The INNO-LiPA assay detected 49 HPV-16 infections, compared with 47 detected by the PapType assay. The INNO-LiPA assay detected amplifiable DNA in 59 (91%) biopsy specimens, compared with 57 (88%) specimens for which amplifiable DNA was detected by the PapType assay. The two genotyping assays were highly comparable.
authors.affiliation: Department of Microbiology and Infectious Diseases, The Royal Women's Hospital, Victoria 3052, Australia. s.tan39@pgrad.unimelb.edu.au
authors.forename: Sarah E
authors.initials: SE
authors.lastname: Tan
authors.forename: Suzanne M
authors.initials: SM
authors.lastname: Garland
authors.forename: Alice R
authors.initials: AR
authors.lastname: Rumbold
authors.forename: Sepehr N
authors.initials: SN
authors.lastname: Tabrizi
mesh_terms: D000293:Adolescent; D000328:Adult; D001706:Biopsy; D004279:DNA, Viral / Q000235:genetics; D005260:Female; D005838:Genotype; D006801:Humans; D008875:Middle Aged; D025202:Molecular Diagnostic Techniques / Q000379:methods*; D027383:Papillomaviridae / Q000145:classification / Q000302:isolation & purification*; D030361:Papillomavirus Infections / Q000175:diagnosis* / Q000821:virology; D012680:Sensitivity and Specificity; D014773:Virology / Q000379:methods; D014844:Vulva / Q000821:virology*; D014846:Vulvar Neoplasms / Q000821:virology*; D055815:Young Adult
chemical_list: D004279:DNA, Viral