title: Effect of primary percutaneous coronary intervention on myocardial repolarization.
abstract: OBJECTIVE
  We aimed to investigate the effect of coronary perfusion on QT interval dispersion in patients with acute myocardial infarction (MI).
  
  
  METHODS
  Seventy-seven consecutive patients who had undergone primary percutaneous coronary intervention (PCI) for a first ST segment elevation MI during the first 12 h of symptom onset were included in the study. After achievement of thrombolysis in MI (TIMI) 3 flow of the infarct-related artery, corrected TIMI frame count (cTFC) and TIMI myocardial perfusion grade (TMPG) were measured. ECGs were performed in the following manner: at baseline, within 1 h after completion of the procedure, 24 h after the procedure and 48 h after the procedure. The corrected QT dispersion (QTd) and ST segment resolution (STR) were calculated.
  
  
  RESULTS
  There was a difference between the durations of corrected QTd (cQTd) before PCI and cQTd just after PCI. On the first day, cQTd before PCI was significantly more prolonged (52.3 ± 80 vs. 41.5 ± 49, P = 0.05) than cQTd on second day (52.3 ± 80 vs. 37 ± 50, P = 0.001). In the correlation analysis conducted among the durations of cQTd, cTFC and TMPG, no significant association was established. STR was, however, inversely correlated with duration of cQTd.
  
  
  CONCLUSIONS
  Our study results demonstrated that primary percutaneous coronary intervention leads to progressive shortening of QT dispersion in successful reperfusion, even in reduced cTFC.
authors.affiliation: Department of Cardiology, Ataturk Education and Research Hospital, Ankara, Turkey.
authors.forename: Emine
authors.initials: E
authors.lastname: Bilen
authors.forename: Ayşe S
authors.initials: AS
authors.lastname: Yasar
authors.forename: Mehmet
authors.initials: M
authors.lastname: Bilge
authors.forename: Isa O
authors.initials: IO
authors.lastname: Yuksel
authors.forename: Uğur
authors.initials: U
authors.lastname: Aslantas
authors.forename: Mustafa
authors.initials: M
authors.lastname: Kurt
authors.forename: Göktürk
authors.initials: G
authors.lastname: Ipek
authors.forename: Mehmet F
authors.initials: MF
authors.lastname: Karakaş
authors.forename: Ibrahim H
authors.initials: IH
authors.lastname: Tanboğa
mesh_terms: D000368:Aged; D015906:Angioplasty, Balloon, Coronary; D003326:Coronary Circulation; D004562:Electrocardiography; D005260:Female; D006329:Heart Conduction System / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008833:Microcirculation; D008875:Middle Aged; D009203:Myocardial Infarction / Q000503:physiopathology / Q000628:therapy*; D015588:Observer Variation; D011237:Predictive Value of Tests; D015203:Reproducibility of Results; D013997:Time Factors; D016896:Treatment Outcome; D014421:Turkey; D016276:Ventricular Function