title: Transplacental fetal therapy for junctional ectopic tachycardia.
abstract: Junctional ectopic tachycardia (JET) is a rare type of tachyarrhythmia. A 39-year-old woman was transferred to our hospital for fetal tachyarrhythmia at 32 weeks' gestation. Fetal cardiac sonography revealed atrial and ventricular rates of 120-130 and 175-230 bpm, respectively, without 1:1 atrioventricular relationship. As ventricular tachycardia was considered to be the most probable diagnosis, transplacental therapy with digoxin and sotalol was done with partial response. Diagnosis of JET was made after birth. Although fetal JET is rare and prenatal diagnosis and treatment of this condition is still a challenge, differential diagnosis of fetal tachyarrhythmia should include this disorder.
authors.affiliation: Department of Obstetrics, Center for Perinatal Medicine, Nagano Children's Hospital, 3100 Toyoshina, Azumino, Nagano 399-8288, Japan.
authors.forename: Kaori
authors.initials: K
authors.lastname: Ishikawa
authors.forename: Akihiko
authors.initials: A
authors.lastname: Kikuchi
authors.forename: Hikoro
authors.initials: H
authors.lastname: Matsui
authors.forename: Shunsuke
authors.initials: S
authors.lastname: Tamaru
authors.forename: Shinya
authors.initials: S
authors.lastname: Imada
authors.forename: Tsuguhiro
authors.initials: T
authors.lastname: Horikoshi
authors.forename: Kimiyo
authors.initials: K
authors.lastname: Takagi
mesh_terms: D000328:Adult; D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use*; D004077:Digoxin / Q000627:therapeutic use*; D004562:Electrocardiography; D005260:Female; D006801:Humans; D011247:Pregnancy; D011256:Pregnancy Outcome; D013015:Sotalol / Q000627:therapeutic use*; D013613:Tachycardia, Ectopic Junctional / Q000000981:diagnostic imaging* / Q000188:drug therapy*; D016216:Ultrasonography, Prenatal / Q000379:methods*
chemical_list: D000889:Anti-Arrhythmia Agents; D004077:Digoxin; D013015:Sotalol