title: Genetic characterization of equine adenovirus type 1.
abstract: Two known serotypes of equine adenovirus (EAdV), equine adenovirus type 1 (EAdV-1) and equine adenovirus type 2 (EAdV-2) have been isolated from horses. EAdV-1 is predominantly associated with upper respiratory tract infections while EAdV-2 appears to be associated with gastrointestinal infections in horses. In this report the EAdV-1 genome has been sequenced for the first time. The EAdV-1 genome encoded genes are characteristic of the Mastadenovirus genus such as protein V and IX. Unexpectedly, phylogenetic reconstructions also revealed a close relationship between EAdV-1 and two recently characterized bat adenoviruses. The results of this study suggest that EAdV-1 may share a common ancestor with canine and bat adenoviruses.
authors.affiliation: School of Biomedical Sciences, Charles Sturt University, Wagga Wagga, NSW 2678, Australia.
authors.forename: Heather M A
authors.initials: HM
authors.lastname: Cavanagh
authors.forename: Timothy J
authors.initials: TJ
authors.lastname: Mahony
authors.forename: Thiru
authors.initials: T
authors.lastname: Vanniasinkam
mesh_terms: D000256:Adenoviridae / Q000145:classification* / Q000235:genetics*; D000257:Adenoviridae Infections / Q000662:veterinary* / Q000821:virology; D000818:Animals; D001483:Base Sequence; D016679:Genome, Viral / Q000235:genetics*; D006734:Horse Diseases / Q000821:virology*; D006736:Horses; D017921:Mastadenovirus / Q000145:classification / Q000235:genetics; D010802:Phylogeny