title: [A case of locally advanced non-small-cell lung cancer complicated with chronic renal failure and gastric cancer, successfully treated with weekly docetaxel and concurrent thoracic radiotherapy].
abstract: A standard therapy is not established for locally advanced non-small-cell lung cancer(NSCLC)complicated with chronic renal failure, although some cases of the disease have been reported. We report a case of a locally advanced squamous cell carcinoma of the lung, complicated with chronic renal failure. He was successfully treated with weekly docetaxel(DOC)and concurrent thoracic radiotherapy, and no deterioration of renal function was observed. In locally advanced NSCLC complicated with renal dysfunction, treatment with weekly DOC and concurrent thoracic radiotherapy is considered to be a therapeutic option. Since radiation pneumonitis occurred in the present case, the accumulation and precise analysis of applicable cases is an important subject for future consideration.
authors.affiliation: Dept. of Internal Medicine, Toyonaka Municipal Hospital.
authors.forename: Takayuki
authors.initials: T
authors.lastname: Takimoto
authors.forename: Akane
authors.initials: A
authors.lastname: Watanabe
authors.forename: Tasuku
authors.initials: T
authors.lastname: Nakabori
authors.forename: Akio
authors.initials: A
authors.lastname: Osa
authors.forename: Satomu
authors.initials: S
authors.lastname: Morita
authors.forename: Haruko
authors.initials: H
authors.lastname: Terada
authors.forename: Takashi
authors.initials: T
authors.lastname: Iwazawa
authors.forename: Kinya
authors.initials: K
authors.lastname: Abe
mesh_terms: D000368:Aged; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D002289:Carcinoma, Non-Small-Cell Lung / Q000188:drug therapy* / Q000473:pathology / Q000532:radiotherapy; D003131:Combined Modality Therapy; D000077143:Docetaxel; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications*; D008175:Lung Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000532:radiotherapy; D008297:Male; D009367:Neoplasm Staging; D016609:Neoplasms, Second Primary / Q000150:complications / Q000188:drug therapy*; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000473:pathology; D043823:Taxoids / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D000970:Antineoplastic Agents; D043823:Taxoids; D000077143:Docetaxel