title: Confusion and SIRPIDs regress with parenteral lorazepam.
abstract: Stimulus-induced rhythmic, periodic or ictal discharges (SIRPIDs) are EEG epileptiform periodic discharges (PD) induced by arousal. SIRPIDs lie along an ictal-interictal continuum with debate regarding urgency of treatment. In a patient with SIRPIDs, aphasia and confusion, i.v. lorazepam during EEG resulted in improved level of consciousness, return of verbal interaction and regression of SIRPIDs. This suggests that some forms of SIRPIDs may be associated with an ictal confusional state.
authors.affiliation: Department of Neurology, The Johns Hopkins Bayview Medical Center, Baltimore, MD, USA. pkaplan@jhmi.edu
authors.forename: Peter W
authors.initials: PW
authors.lastname: Kaplan
authors.forename: Josh
authors.initials: J
authors.lastname: Duckworth
mesh_terms: D000368:Aged; D000925:Anticoagulants / Q000627:therapeutic use; D000927:Anticonvulsants / Q000627:therapeutic use*; D003221:Confusion / Q000188:drug therapy* / Q000209:etiology* / Q000523:psychology; D003244:Consciousness Disorders; D048909:Diabetes Complications; D004569:Electroencephalography; D005260:Female; D006801:Humans; D008140:Lorazepam / Q000627:therapeutic use*; D012640:Seizures / Q000150:complications* / Q000188:drug therapy* / Q000523:psychology; D013226:Status Epilepticus / Q000150:complications / Q000188:drug therapy; D014859:Warfarin / Q000627:therapeutic use
chemical_list: D000925:Anticoagulants; D000927:Anticonvulsants; D014859:Warfarin; D008140:Lorazepam