title: A new bisabolene from Stevia tomentosa.
abstract: The new sesquiterpene (1R,2R,3R,6R,7S)-1-acetoxy-2,3-dihydroxy-2,3-dihydrobisabolene (3) together with ten known terpenes and three known flavonoids were isolated from the aerial parts and from the roots of Stevia tomentosa. The structure of 3 follows from spectral studies, the relative chirality at C-3 follows from 1H NMR coupling constants comparison with the corresponding calculated values obtained by applying a generalized Karplus-type relationship to the dihedral angles of model compounds, and the absolute configuration is assumed in analogy to known (2R,3R,6R,7S)-2,3-epoxy-2,3-dihydrobisabolen-1-one (2).
authors.affiliation: Area Académica de Química, Universidad Autónoma del Estado de Hidalgo, Km 4.5 Carretera Pachuca-Tulancingo, Mineral de la Reforma, Hidalgo, 42184 Mexico.
authors.forename: Alejandro
authors.initials: A
authors.lastname: Valdez-Calderón
authors.forename: J Martín
authors.initials: JM
authors.lastname: Torres-Valenci
authors.forename: J Jesús
authors.initials: JJ
authors.lastname: Manríquez-Torres
authors.forename: René
authors.initials: R
authors.lastname: Velázquez-Jiménez
authors.forename: Mario A
authors.initials: MA
authors.lastname: Gómez-Hurtado
authors.forename: Luisa U
authors.initials: LU
authors.lastname: Román-Marín
authors.forename: Juan D
authors.initials: JD
authors.lastname: Hernández-Hernández
authors.forename: Carlos M
authors.initials: CM
authors.lastname: Cerda-García-Rojas
authors.forename: Pedro
authors.initials: P
authors.lastname: Joseph-Nathan
mesh_terms: D015394:Molecular Structure; D035261:Plant Components, Aerial / Q000737:chemistry; D018517:Plant Roots / Q000737:chemistry; D012717:Sesquiterpenes / Q000737:chemistry*; D036625:Stevia / Q000737:chemistry*
chemical_list: C562086:(1R,2R,3R,6R,7S)-1-acetoxy-2,3-dihydroxy-2,3-dihydrobisabolene; D012717:Sesquiterpenes