title: Two new triterpenoids from Lysimachia heterogenea Klatt and evaluation of their cytotoxicity.
abstract: Two new 13,28-epoxy oleanane-type triterpenoids, namely heterogenoside E and F, were isolated from Lysimachia heterogenea Klatt, together with the eight known compounds: palmitic acid, β-stigmasterol, kaempferol, quercetin, hyperin, isorhamnetin, isorhamnetin-3-O-galactopyranoside and anagallisin C. Heterogenoside F possesses acetoxyl groups at the unusual C-21 and C-22 positions of its oleanane skeleton. The cytotoxic activities of anagallisin C, heterogenoside E and F were weak.
authors.affiliation: Tropical Medicine Institute, Guangzhou University of Chinese Medicine, Guangzhou 510405, China.
authors.forename: Xin-An
authors.initials: XA
authors.lastname: Huang
authors.forename: Xiao-Ling
authors.initials: XL
authors.lastname: Shen
authors.forename: Ying-Jie
authors.initials: YJ
authors.lastname: Hu
authors.forename: Ya-Ming
authors.initials: YM
authors.lastname: Liu
authors.forename: Kang-Lun
authors.initials: KL
authors.lastname: Liu
authors.forename: Feng-Xue
authors.initials: FX
authors.lastname: Zhang
authors.forename: Xin-Xin
authors.initials: XX
authors.lastname: Zhou
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D045744:Cell Line, Tumor; D004354:Drug Screening Assays, Antitumor; D006801:Humans; D020128:Inhibitory Concentration 50; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D029623:Primulaceae / Q000737:chemistry*; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D010936:Plant Extracts; D014315:Triterpenes; C568732:heterogenoside E; C568731:heterogenoside F