title: Drug-induced inhibition of tubulin polymerization induces mitochondrion-mediated apoptosis in yeast.
authors.forename: Vanessa
authors.initials: V
authors.lastname: Palermo
authors.forename: Luisa
authors.initials: L
authors.lastname: Pieri
authors.forename: Romano
authors.initials: R
authors.lastname: Silvestri
authors.forename: Giuseppe
authors.initials: G
authors.lastname: La Regina
authors.forename: Claudio
authors.initials: C
authors.lastname: Falcone
authors.forename: Cristina
authors.initials: C
authors.lastname: Mazzoni
mesh_terms: D000970:Antineoplastic Agents / Q000494:pharmacology; D017209:Apoptosis; D002264:Carboxylic Acids / Q000494:pharmacology; D020169:Caspases / Q000235:genetics / Q000378:metabolism; D017353:Gene Deletion; D005800:Genes, Fungal; D006131:Growth Inhibitors / Q000494:pharmacology; D007211:Indoles / Q000494:pharmacology; D008928:Mitochondria / Q000187:drug effects*; D015394:Molecular Structure; D058105:Polymerization; D011758:Pyrroles / Q000494:pharmacology; D012441:Saccharomyces cerevisiae / Q000187:drug effects* / Q000235:genetics / Q000254:growth & development; D029701:Saccharomyces cerevisiae Proteins / Q000235:genetics / Q000378:metabolism; D014404:Tubulin / Q000378:metabolism*
chemical_list: C569685:1-(3,4,5-trimethoxybenzyl)-1H-pyrrole-2-carboxylic acid; C569683:5-bromo-3-((3,4,5-trimethoxyphenyl)thio)-1H indole; D000970:Antineoplastic Agents; D002264:Carboxylic Acids; D006131:Growth Inhibitors; D007211:Indoles; D011758:Pyrroles; D029701:Saccharomyces cerevisiae Proteins; D014404:Tubulin; D020169:Caspases; C456272:MCA1 protein, S cerevisiae