title: An observational study to validate the Satisfaction Measure of the Injection of Growth Hormone Therapy (SMIGHTy) questionnaire.
abstract: OBJECTIVE
  The objective of this study was to psychometrically evaluate a tool to measure adult caregivers' level of satisfaction with the delivery device used to administer injections of recombinant human growth hormone (rhGH) to a child - the Satisfaction Measure of the Injection of Growth Hormone Therapy (SMIGHTy*) questionnaire.
  
  
  METHODS
  One hundred caregivers who administer rhGH to a child using an injection device completed the SMIGHTy questionnaire at baseline and 7-14 days later, and also completed other measures of treatment adherence and treatment satisfaction at baseline.
  
  
  METHODS
  SMIGHTy reliability (inter-item and test-retest) and external validity (association with other study measures) were assessed.
  
  
  RESULTS
  Analyses revealed good inter-item agreement and test-retest reliability for the SMIGHTy questionnaire. External validity, measured by associations with adherence and other measures of treatment satisfaction, was high.
  
  
  CONCLUSIONS
  This study assessed only adult caregivers; the instrument was not validated for use by young or adult patients.
  
  
  CONCLUSIONS
  The SMIGHTy instrument is more comprehensive than existing instruments for assessing the growth hormone treatment experience. It is multidimensional, assesses both positive and negative aspects of the treatment experience (Device Satisfaction, Negative Events, Benefits), and has separate measures of overall satisfaction and preference.
authors.affiliation: Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.
authors.forename: Richard R
authors.initials: RR
authors.lastname: Rubin
authors.forename: Mark
authors.initials: M
authors.lastname: Peyrot
authors.forename: Catherine P
authors.initials: CP
authors.lastname: Metzinger
authors.forename: Yaping
authors.initials: Y
authors.lastname: Xu
authors.forename: Barbara
authors.initials: B
authors.lastname: Lippe
authors.forename: Leah
authors.initials: L
authors.lastname: McCormack
authors.forename: Daniel Aaron
authors.initials: DA
authors.lastname: Davis
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D003695:Delivery of Health Care; D005260:Female; D020249:Hormone Replacement Therapy; D019382:Human Growth Hormone / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D017060:Patient Satisfaction; D011795:Surveys and Questionnaires
chemical_list: D019382:Human Growth Hormone