title: Successful treatment of a paraneoplastic pemphigus in a teenager using plasmapheresis, corticosteroids and tumour resection.
abstract: Paraneoplastic pemphigus (PNP) is a severe autoimmune blistering disease. Bronchiolitis obliterans (BO) is a common complication of PNP, is the major cause of death. PNP is rarely seen before the age of 18 years, and the prognosis is poor because of BO. We report a 16-year-old girl with the typical findings of PNP associated with Castleman's tumour. She was treated with tumour resection in combination with plasmapheresis and corticosteroids. Fifteen months after the operation, the patient had recovered without the development of BO.
authors.affiliation: Department of Dermatology, Peking University First Hospital, Beijing, China.
authors.forename: L
authors.initials: L
authors.lastname: Jing
authors.forename: Z
authors.initials: Z
authors.lastname: Shan
authors.forename: H
authors.initials: H
authors.lastname: Yongchu
authors.forename: C
authors.initials: C
authors.lastname: Xixue
authors.forename: Z
authors.initials: Z
authors.lastname: Xuejun
mesh_terms: D000293:Adolescent; D005871:Castleman Disease / Q000150:complications* / Q000628:therapy; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use*; D006801:Humans; D010257:Paraneoplastic Syndromes / Q000628:therapy*; D010392:Pemphigus / Q000628:therapy*; D010956:Plasmapheresis; D011239:Prednisolone / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D005938:Glucocorticoids; D011239:Prednisolone