title: Naturally acquired rabies virus infections in wild-caught bats.
abstract: The study of a zoonotic disease requires an understanding of the disease incidence in animal reservoirs. Rabies incidence in bats submitted to diagnostic laboratories does not accurately reflect the true incidence in wild bat populations as a bias exists for testing bats that have been in contact with humans or pets. This article details the rabies incidence in two species of bats collected from natural settings without such bias. In this study, brain smears from 0.6% and 2.5% of wild-caught and apparently healthy Tadarida brasiliensis and Eptesicus fuscus, respectively, were positive for rabies virus (RV) antigen. Conversely, 92% of the grounded T. brasiliensis were positive for RV. Serology performed on captive colony and sick bats reveal an immune response to rabies. This work illustrates the complex interplay between immunity, disease state, and the conundrum of RV maintenance in bats.
authors.affiliation: Department of Infectious Diseases, Wadsworth Center, Slingerlands, New York 12159, USA. add02@health.state.ny.us
authors.forename: April
authors.initials: A
authors.lastname: Davis
authors.forename: Paul
authors.initials: P
authors.lastname: Gordy
authors.forename: Robert
authors.initials: R
authors.lastname: Rudd
authors.forename: Jodie A
authors.initials: JA
authors.lastname: Jarvis
authors.forename: Richard A
authors.initials: RA
authors.lastname: Bowen
mesh_terms: D000818:Animals; D000956:Antigens, Viral / Q000302:isolation & purification; D001921:Brain / Q000821:virology; D002685:Chiroptera; D011818:Rabies / Q000453:epidemiology / Q000662:veterinary* / Q000821:virology; D011820:Rabies virus / Q000302:isolation & purification*; D012469:Salivary Glands / Q000821:virology
chemical_list: D000956:Antigens, Viral