title: Severity of mitral stenosis and left ventricular mechanics: a speckle tracking study.
abstract: BACKGROUND
  It has been shown that mitral stenosis (MS) impairs left ventricular (LV) systolic function; however, this issue has not been studied comprehensively. We aimed to evaluate the role of 2D strain in the assessment of subclinical LV systolic dysfunction in patients with MS.
  
  
  METHODS
  Seventy-two patients with isolated MS (mild, moderate and severe) and 31 healthy control subjects constituted the study population. 2D echocardiography images were obtained from LV apical 4-chamber (4C), long axis (LAX), and 2-chamber (2C) views. Peak longitudinal strain and strain rate (Sr) were obtained from 4C, LAX, and 2C views. Global strain and Sr were calculated by averaging the three apical views.
  
  
  RESULTS
  There were no significant differences in LV ejection fraction and LV systolic or diastolic dimensions between the groups. Patients with MS had significantly lower LV longitudinal strain and Sr measurements than the control group. In addition, there were no significant differences in MS subgroups with respect to LV strain and Sr measurements.
  
  
  CONCLUSIONS
  We demonstrated that patients with MS had lower LV functions using 2D strain imaging, and this is independent of the hemodynamic severity of MS. In the detection of subclinical LV dysfunction in patients with MS, 2D strain imaging appears to be useful.
authors.affiliation: Ankara Ataturk Education and Research Hospital, Ankara, Turkey.
authors.forename: Emine
authors.initials: E
authors.lastname: Bilen
authors.forename: Mustafa
authors.initials: M
authors.lastname: Kurt
authors.forename: Ibrahim Halil
authors.initials: IH
authors.lastname: Tanboga
authors.forename: Ahmet
authors.initials: A
authors.lastname: Kaya
authors.forename: Turgay
authors.initials: T
authors.lastname: Isik
authors.forename: Mehmet
authors.initials: M
authors.lastname: Ekinci
authors.forename: Mehmet Mustafa
authors.initials: MM
authors.lastname: Can
authors.forename: Mehmet Fatih
authors.initials: MF
authors.lastname: Karakas
authors.forename: Vecih
authors.initials: V
authors.lastname: Oduncu
authors.forename: Ednan
authors.initials: E
authors.lastname: Bayram
authors.forename: Enbiya
authors.initials: E
authors.lastname: Aksakal
authors.forename: Serdar
authors.initials: S
authors.lastname: Sevimli
mesh_terms: D000328:Adult; D000368:Aged; D016022:Case-Control Studies; D004452:Echocardiography; D005260:Female; D006352:Heart Ventricles / Q000000981:diagnostic imaging*; D006801:Humans; D008297:Male; D008875:Middle Aged; D008946:Mitral Valve Stenosis / Q000150:complications / Q000000981:diagnostic imaging*; D012720:Severity of Illness Index; D018487:Ventricular Dysfunction, Left / Q000150:complications / Q000000981:diagnostic imaging*