title: Acute disseminated encephalomyelitis following influenza vaccination.
abstract: BACKGROUND
  Approximately 5% of cases of acute disseminated encephalomyelitis are preceded by vaccination within 1 month prior to symptom onset. This occurs rarely following influenza immunization.
  
  
  METHODS
  Case presentation and literature review.
  
  
  RESULTS
  A 75-year-old woman developed acute disseminated encephalomyelitis within 3 weeks of receiving the seasonal influenza vaccine. The patient subsequently passed away, despite treatment with methylprednisolone and plasma exchange therapy.
  
  
  CONCLUSIONS
  The literature on post-influenza vaccination encephalomyelitis is limited. The majority of published cases had favourable outcomes following treatment with intravenous methylprednisolone. Given the limited number of cases, no incidence estimates have been published.
authors.affiliation: UBC Hospital, Vancouver, BC, Canada. ashkan.sho@gmail.com
authors.forename: A
authors.initials: A
authors.lastname: Shoamanesh
authors.forename: A
authors.initials: A
authors.lastname: Traboulsee
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage; D002675:Child, Preschool; D004673:Encephalomyelitis, Acute Disseminated / Q000139:chemically induced* / Q000175:diagnosis*; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007252:Influenza Vaccines / Q000008:administration & dosage* / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D010951:Plasma Exchange; D011239:Prednisolone / Q000008:administration & dosage; D014611:Vaccination / Q000009:adverse effects*
chemical_list: D000893:Anti-Inflammatory Agents; D007252:Influenza Vaccines; D011239:Prednisolone