title: Retrospective analysis of risk factors and predictors of intraoperative complications in neuraxial blocks at Faculdade de Medicina de Botucatu-UNESP.
abstract: OBJECTIVE
  Cardiovascular changes associated with neuraxial blocks are a cause of concern due to their frequency and because some of them can be considered physiological effects triggered by the sympathetic nervous system blockade. The objective of this study was to evaluate intraoperative cardiovascular complications and predictive factors associated with neuraxial blocks in patients ≥ 18 years of age undergoing non-obstetric procedures over an 18-year period in a tertiary university hospital--HCFMB-UNESP.
  
  
  METHODS
  A retrospective analysis of the following complications was undertaken: hypertension, hypotension, sinus bradycardia, and sinus tachycardia. These complications were correlated with anesthetic technique, physical status (ASA), age, gender, and preoperative co-morbidities. The Tukey test for comparisons among proportions and logistic regression was used for statistical analysis.
  
  
  RESULTS
  32,554 patients underwent neuraxial blocks. Intraoperative complications mentioned included hypotension (n=4,109), sinus bradycardia (n=1,107), sinus tachycardia (n=601), and hypertension (n=466). Hypotension was seen more often in patients undergoing continuous subarachnoid anesthesia (29.4%, OR=2.39), ≥ 61 years of age, and female (OR=1.27).
  
  
  CONCLUSIONS
  Intraoperative hypotension and bradycardia were the complications observed more often. Hypotension was related to anesthetic technique (CSA), increased age, and female. Tachycardia and hypertension may not have been directly related to neuraxial blocks.
authors.affiliation: Faculdade de Medicina de Botucatu-UNESP, Brazil. idmblh@uol.com.br
authors.forename: Ivan Dias Fernandes
authors.initials: ID
authors.lastname: Pereira
authors.forename: Marcela Miguel
authors.initials: MM
authors.lastname: Grando
authors.forename: Pedro Thadeu Galvão
authors.initials: PT
authors.lastname: Vianna
authors.forename: José Reinaldo Cerqueira
authors.initials: JR
authors.lastname: Braz
authors.forename: Yara Marcondes Machado
authors.initials: YM
authors.lastname: Castiglia
authors.forename: Luís Antônio
authors.initials: LA
authors.lastname: Vane
authors.forename: Norma Sueli Pinheiro
authors.initials: NS
authors.lastname: Módolo
authors.forename: Paulo
authors.initials: P
authors.lastname: do Nascimento
authors.forename: Rosa Beatriz
authors.initials: RB
authors.lastname: Amorim
authors.forename: Geraldo Rolim
authors.initials: GR
authors.lastname: Rodrigues
authors.forename: Leandro Gobbo
authors.initials: LG
authors.lastname: Braz
authors.forename: Eliana Marisa
authors.initials: EM
authors.lastname: Ganem
mesh_terms: D000293:Adolescent; D000328:Adult; D001919:Bradycardia / Q000209:etiology; D005260:Female; D006801:Humans; D006973:Hypertension / Q000209:etiology; D007022:Hypotension / Q000209:etiology; D007431:Intraoperative Complications / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D009407:Nerve Block / Q000009:adverse effects*; D012189:Retrospective Studies; D012307:Risk Factors; D013610:Tachycardia / Q000209:etiology; D055815:Young Adult