title: Coarse particles and mortality in three Chinese cities: the China Air Pollution and Health Effects Study (CAPES).
abstract: Evidence concerning the health risks of coarse particles (PM(10-2.5)) is limited. There have been no multi-city epidemiologic studies of PM(10-2.5) in developing Asian countries. We examine the short-term association between PM(10-2.5) and daily mortality in three Chinese cities: Beijing, Shanghai, and Shenyang. PM(10-2.5) concentrations were estimated by subtracting PM(2.5) from PM(10) measurements. Data were analyzed using the over-dispersed generalized linear Poisson models. The average daily concentrations of PM(10-2.5) were 101 μg/m(3) for Beijing (2007-2008), 50 μg/m(3) for Shanghai (2004-2008), and 49 μg/m(3) for Shenyang (2006-2008). In the single-pollutant models, the three-city combined analysis showed significant associations between PM(10-2.5) and daily mortality from both total non-accidental causes and from cardiopulmonary diseases. A 10-μg/m(3) increase in 1-day lagged PM(10-2.5) was associated with a 0.25% (95% CI: 0.08 to 0.42) increase in total mortality, 0.25% (95% CI: 0.10 to 0.40) increase in cardiovascular mortality, and 0.48% (95% CI: 0.20 to 0.76) increase in respiratory mortality. However, these associations became statistically insignificant after adjustment for PM(2.5). PM(2.5) was significantly associated with mortality both before and after adjustment for PM(10-2.5). In conclusion, there were no statistically significant associations between PM(10-2.5) and daily mortality after adjustment for PM(2.5) in the three Chinese cities.
authors.affiliation: School of Public Health, Key Lab of Public Health Safety of the Ministry of Education, Fudan University, Shanghai, China.
authors.forename: Renjie
authors.initials: R
authors.lastname: Chen
authors.forename: Yi
authors.initials: Y
authors.lastname: Li
authors.forename: Yanjun
authors.initials: Y
authors.lastname: Ma
authors.forename: Guowei
authors.initials: G
authors.lastname: Pan
authors.forename: Guang
authors.initials: G
authors.lastname: Zeng
authors.forename: Xiaohui
authors.initials: X
authors.lastname: Xu
authors.forename: Bingheng
authors.initials: B
authors.lastname: Chen
authors.forename: Haidong
authors.initials: H
authors.lastname: Kan
mesh_terms: D002318:Cardiovascular Diseases / Q000139:chemically induced* / Q000401:mortality*; D002681:China / Q000453:epidemiology; D002947:Cities; D004784:Environmental Monitoring / Q000379:methods / Q000706:statistics & numerical data*; D062665:Epidemiological Monitoring; D016014:Linear Models; D010316:Particle Size; D052638:Particulate Matter / Q000032:analysis / Q000633:toxicity*
chemical_list: D052638:Particulate Matter