title: Recovery of advanced atrioventricular block by cilostazol.
abstract: We describe a case of advanced atrioventricular (AV) block, in which treatment with cilostazol was effective in recovering the AV conduction. The patient was referred to our hospital for close examination of the advanced AV block and permanent pacemaker implantation. Although the patient had experienced third-degree AV block with occasional AV synchrony for more than two days, the AV conduction completely recovered after treatment with oral cilostazol at 200 mg/day. Here we discuss the possible mechanism of the improvement in the AV conduction by cilostazol.
authors.affiliation: Cardiovascular Respiratory and Neurology Division, Department of Internal Medicine, Asahikawa Medical College, Japan.
authors.forename: Asami
authors.initials: A
authors.lastname: Nimura
authors.forename: Nobuyuki
authors.initials: N
authors.lastname: Sato
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Sakuragi
authors.forename: Satoshi
authors.initials: S
authors.lastname: Koyama
authors.forename: Junichi
authors.initials: J
authors.lastname: Maruyama
authors.forename: Ahmed Karim
authors.initials: AK
authors.lastname: Talib
authors.forename: Naoki
authors.initials: N
authors.lastname: Nakagawa
authors.forename: Naka
authors.initials: N
authors.lastname: Sakamoto
authors.forename: Hisanobu
authors.initials: H
authors.lastname: Ota
authors.forename: Yasuko
authors.initials: Y
authors.lastname: Tanabe
authors.forename: Toshiharu
authors.initials: T
authors.lastname: Takeuchi
authors.forename: Yuichiro
authors.initials: Y
authors.lastname: Kawamura
authors.forename: Naoyuki
authors.initials: N
authors.lastname: Hasebe
mesh_terms: D000369:Aged, 80 and over; D054537:Atrioventricular Block / Q000188:drug therapy* / Q000503:physiopathology; D000077407:Cilostazol; D004562:Electrocardiography; D005260:Female; D006329:Heart Conduction System / Q000187:drug effects / Q000503:physiopathology; D006801:Humans; D058987:Phosphodiesterase 3 Inhibitors / Q000494:pharmacology / Q000627:therapeutic use*; D013777:Tetrazoles / Q000494:pharmacology / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D058987:Phosphodiesterase 3 Inhibitors; D013777:Tetrazoles; D000077407:Cilostazol