title: Cerebral venous and sinus thrombosis associated with subcutaneous immunoglobulin injection and oral contraceptive use.
abstract: Although patients of cerebral sinus thrombosis after intravenous immunoglobulin (IVIG) has been previously reported; reports of cerebral venous thrombosis secondary to subcutaneous injection of immunoglobulin (SIG) in conjunction with oral contraceptives are nonexistent in the current literature. We describe here a patient of cerebral venous and sinus thrombosis occurring after the combination of SIG and oral contraceptive use. Furthermore, we shall explore proper clinical precautions for someone who receives IG therapy, especially in conjunction with the use of oral contraceptives.
authors.affiliation: Division of Cerebral Vascular Diseases, Sparrow Health System, Department of Neurology and Ophthalmology, Michigan State University, A-217 Clinical Center, 138 Service Road, East Lansing, MI 48824, USA. minjy@msu.edu
authors.forename: Jiangyong
authors.initials: J
authors.lastname: Min
authors.forename: Archit
authors.initials: A
authors.lastname: Bhatt
authors.forename: Rany
authors.initials: R
authors.lastname: Aburashed
authors.forename: Stephen
authors.initials: S
authors.lastname: Burton
mesh_terms: D003276:Contraceptives, Oral / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007136:Immunoglobulins / Q000009:adverse effects*; D007279:Injections, Subcutaneous / Q000009:adverse effects; D018810:Magnetic Resonance Angiography; D008279:Magnetic Resonance Imaging; D012851:Sinus Thrombosis, Intracranial / Q000139:chemically induced* / Q000150:complications / Q000175:diagnosis; D020246:Venous Thrombosis / Q000139:chemically induced* / Q000150:complications / Q000175:diagnosis; D055815:Young Adult
chemical_list: D003276:Contraceptives, Oral; D007136:Immunoglobulins