title: Cosmeceuticals for cellulite.
abstract: Cellulite is characterized by alterations to the skin surface, presenting as dimpled or puckered skin of the buttocks and posterior and lateral thighs. It mainly affects women. Cellulite occurrence is believed to be due to structural, inflammatory, morphological and biochemical alterations of the subcutaneous tissue. However, its pathogenesis is not completely understood. Topical treatments for cellulite include many agents, such those that increase the microcirculation flow, agents that reduce lipogenesis and promote lipolysis, agents that restore the normal structure of dermis and subcutaneous tissue, and agents that scavenge free radicals or prevent their formation. There are many cosmetic and medical treatments for cellulite. However, there is little clinical evidence of an improvement in cellulite, and none have been shown to lead to its resolution. The successful treatment of cellulite will ultimately depend upon our understanding of the physiopathology of cellulite adipose tissue.
authors.affiliation: Brazilian Center for Studies in Dermatology, Porto Alegre, RS. doris@hexsel.com.br
authors.forename: Doris
authors.initials: D
authors.lastname: Hexsel
authors.forename: Mariana
authors.initials: M
authors.lastname: Soirefmann
mesh_terms: D000273:Adipose Tissue / Q000098:blood supply / Q000187:drug effects* / Q000473:pathology; D003358:Cosmetics / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008833:Microcirculation / Q000187:drug effects; D009765:Obesity / Q000628:therapy*; D008517:Phytotherapy; D028321:Plant Preparations / Q000627:therapeutic use*; D040521:Subcutaneous Tissue / Q000187:drug effects* / Q000473:pathology
chemical_list: D003358:Cosmetics; D028321:Plant Preparations