title: Is synaesthesia one condition or many? A large-scale analysis reveals subgroups.
abstract: Synaesthesia is a broadly defined neural phenomenon in which stimulation of a sense or concept triggers a second perception not normally associated with the stimulus. For example, letters or numbers may trigger a colour experience, sounds may trigger a taste sensation, or tastes may trigger a feeling of touch. Dozens of forms of synaesthesia have been reported, but the relationship between the different forms has not been studied: is someone with a particular form of synaesthesia likely to possess other types? If so, which ones? As an inroad to illuminating underlying mechanisms, we here examine which different synaesthesia types tend to co-occur. We analyzed reports of the forms of synaesthesia experienced by 19,133 participants who completed the Synaesthesia Battery (Eagleman, Kagan, Nelson, Sagaram, & Sarma, 2007), using correlation analysis, exploratory factor analysis (EFA), confirmatory factor analysis (CFA), and multidimensional scaling (MDS). Our analyses converged on the finding of five distinct groupings of synaesthesia forms. We label these coloured sequence synaesthesias (CSSs), coloured music synaesthesias, non-visual sequela synaesthesias, spatial sequence synaesthesia (SSS), and coloured sensation synaesthesias. Collectively, our findings reveal that synaesthesia is an umbrella term that encompasses several distinct groups with independent probabilities of expression, and this may in turn suggest distinct underlying mechanisms and the possibility of different genetic bases.
authors.affiliation: Department of Neuroscience, Baylor College of Medicine, Houston, Texas, USA.
authors.forename: Scott
authors.initials: S
authors.lastname: Novich
authors.forename: Sherry
authors.initials: S
authors.lastname: Cheng
authors.forename: David M
authors.initials: DM
authors.lastname: Eagleman
mesh_terms: D001244:Association; D005163:Factor Analysis, Statistical; D005260:Female; D006801:Humans; D008297:Male; D010465:Perception / Q000145:classification* / Q000502:physiology*; D010551:Personality; D012677:Sensation; D013223:Statistics as Topic