title: Comparative survival of uncemented acetabular components following primary total hip arthroplasty.
abstract: BACKGROUND
  Since their initial introduction in the early 1980s, uncemented acetabular components have become the preferred implant type for the majority of hip arthroplasties performed in the United States. The purpose of the present study was to compare differences in the survival of uncemented acetabular components following primary total hip arthroplasty.
  
  
  METHODS
  The study population included 7989 patients who had undergone 9584 primary total hip arthroplasties with twenty different types of uncemented acetabular components at the Mayo Clinic from January 1984 to December 2004. The overall rate of survival as well as the rate of survival free of revision for specific reasons (aseptic loosening, wear, osteolysis) were compared among the different components using age and sex-adjusted Cox proportional hazards regression models.
  
  
  RESULTS
  The risk of acetabular cup revision was significantly higher for beaded and hydroxyapatite-coated designs as compared with titanium wire mesh designs. Cross-linked polyethylene performed better than conventional polyethylene, but this finding did not reach significance. Elevated liners were associated with a significantly higher risk of cup revision due to aseptic loosening.
  
  
  CONCLUSIONS
  There are significant differences in the long-term survival of different types of uncemented acetabular components following total hip arthroplasty. The increased risk of revisions in the second decade after the initial total hip arthroplasty is a concern and is largely due to a steady increase in revisions because of polyethylene wear, osteolysis, and component loosening more than ten years after the time of the index arthroplasty.
authors.affiliation: Mayo Clinic, Rochester, Minnesota, USA.
authors.forename: James L
authors.initials: JL
authors.lastname: Howard
authors.forename: Hilal Maradit
authors.initials: HM
authors.lastname: Kremers
authors.forename: Youlonda A
authors.initials: YA
authors.lastname: Loechler
authors.forename: Cathy D
authors.initials: CD
authors.lastname: Schleck
authors.forename: William S
authors.initials: WS
authors.lastname: Harmsen
authors.forename: Daniel J
authors.initials: DJ
authors.lastname: Berry
authors.forename: Miguel E
authors.initials: ME
authors.lastname: Cabanela
authors.forename: Arlen D
authors.initials: AD
authors.lastname: Hanssen
authors.forename: Mark W
authors.initials: MW
authors.lastname: Pagnano
authors.forename: Robert T
authors.initials: RT
authors.lastname: Trousdale
authors.forename: David G
authors.initials: DG
authors.lastname: Lewallen
mesh_terms: D000077:Acetabulum / Q000601:surgery; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D019644:Arthroplasty, Replacement, Hip / Q000009:adverse effects / Q000379:methods*; D001843:Bone Cements; D015331:Cohort Studies; D016001:Confidence Intervals; D005260:Female; D005500:Follow-Up Studies; D006622:Hip Prosthesis; D006801:Humans; D053208:Kaplan-Meier Estimate; D008297:Male; D008875:Middle Aged; D016016:Proportional Hazards Models; D011474:Prosthesis Design; D011475:Prosthesis Failure; D020127:Recovery of Function; D012042:Registries; D012086:Reoperation / Q000379:methods; D012189:Retrospective Studies; D018570:Risk Assessment; D012737:Sex Factors; D013997:Time Factors; D016896:Treatment Outcome; D014481:United States
chemical_list: D001843:Bone Cements