title: Bioactive constituents from Michelia champaca.
abstract: (-)-Anonaine (1), (-)-asimilobine (2), (-)-nuciferine (3), (-)-anolobine (4), (-)-romerine (5), (-)-N-acetylanonaine (6), liriodenine (7), (+)-syringaresinol (8), N-trans-feruloyltyramine (9), N-cis-feruloyltyramine (10), scopoletin (11), 4-acetonyl-3,5-dimethoxy-p-quinol (12), vanillin (13), vanillic acid (14), syringic acid (15), beta-sitosterol (16) and stigmasterol (17) were isolated from branches of Michelia champaca L. In addition, a cell proliferation assay of five of the isolated compounds on human breast and lung cancer cells showed that liriodenine (7) was the strongest inhibitor.
authors.affiliation: School of Medical and Health Sciences, Fooyin University, Kaohsiung 831, Taiwan, ROC.
authors.forename: Yu-Ting
authors.initials: YT
authors.lastname: Yeh
authors.forename: Jin-Cherng
authors.initials: JC
authors.lastname: Huang
authors.forename: Po-Lin
authors.initials: PL
authors.lastname: Kuo
authors.forename: Chung-Yi
authors.initials: CY
authors.lastname: Chen
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry* / Q000494:pharmacology* / Q000627:therapeutic use; D001943:Breast Neoplasms / Q000188:drug therapy; D045744:Cell Line, Tumor; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy; D029562:Magnoliaceae / Q000737:chemistry*; D018547:Plant Stems / Q000737:chemistry*
chemical_list: D000972:Antineoplastic Agents, Phytogenic