title: [Modern three-dimensional conformal craniospinal radiotherapy].
abstract: The main problem of craniospinal irradiation (CSI) is the matching of the fields. The use of a suitable technique is very important because matching of the fields is necessary to use for the optimal cancer irradiation of the long planning target volume (PTV). Since 2007, 8 patients have received CT-based, 3D-planned conformal CSI in our Institute. Patient immobilization was made in prone position in a vacuum bed, using skull and pelvis masks. Organ-at-risk (OAR) contours were made by radiographers. PTV was contoured by radiation oncologists. The prescribed dose to the PTV was 36 Gy with 1.8 Gy dose per fraction. In the planning process the following aspects were taken under consideration: all points of the PTV had to receive at least 95% of the prescribed dose (according to ICRU 50, 62); at junction field edges the overlapping parts were eliminated using a multisegmental technique, where the adjacent segment ends of the neighbouring fields were shifted two times 2 cm, so that the three equally weighted segments used in one field had 2-2 cm distance from each other. In the CSI planning the shape of the patient and so the length of the PTV has made a big emphasis on determining the number of field matching. Thus in some cases instead of two, only one field matching was sufficient - this could be achieved by increasing the source-to-skin distance (SSD) of the fields. The verification made with a solid-water phantom justified the precision of the field matching. The offset used at junction field edges in between one treatment facilitates the verification of field matching - and so the patient positioning. Thus the possibility of having overdosed regions could be reduced, which was very important from a radiation biological point of view.
authors.affiliation: Onkoterápiás Intézet, Pécsi Tudományegyetem, ÁOK KK, Pécs, Hungary. zsolt.sebestyen@aok.pte.hu
authors.forename: Zsolt
authors.initials: Z
authors.lastname: Sebestyén
authors.forename: Péter
authors.initials: P
authors.lastname: Kovács
authors.forename: Akos
authors.initials: A
authors.lastname: Gulybán
authors.forename: Róbert
authors.initials: R
authors.lastname: Farkas
authors.forename: Szabolcs
authors.initials: S
authors.lastname: Bellyei
authors.forename: András
authors.initials: A
authors.lastname: Szigeti
authors.forename: Dóra Földvári
authors.initials: DF
authors.lastname: Gallainé
authors.forename: László
authors.initials: L
authors.lastname: Mangel
mesh_terms: D001932:Brain Neoplasms / Q000532:radiotherapy*; D004806:Ependymoma / Q000532:radiotherapy; D006801:Humans; D021621:Imaging, Three-Dimensional; D008527:Medulloblastoma / Q000532:radiotherapy; D016684:Prone Position; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted; D020266:Radiotherapy, Conformal / Q000379:methods*; D016896:Treatment Outcome