title: Lymphomatosis cerebri: clinical characteristics, neuroimaging, and pathological findings.
abstract: Lymphomatosis cerebri is a rare variant of primary central nervous system lymphoma. We present a case involving a 56-year-old immunocompetent woman who complained of rapid deterioration of her higher brain function over a 4-month period. Magnetic resonance imaging showed extensive white-matter lesions. During brain biopsy, a diffusely infiltrating lymphoma with distinctive immunohistochemical features was detected. Awareness of this unique presentation and early tissue diagnosis provide the best hope for instituting appropriate treatments.
authors.affiliation: Department of Neurosurgery, Faculty of Medical Sciences, University of Fukui, Fukui, Japan. kitai@u-fukui.ac.jp
authors.forename: Ryuhei
authors.initials: R
authors.lastname: Kitai
authors.forename: Norichika
authors.initials: N
authors.lastname: Hashimoto
authors.forename: Kouji
authors.initials: K
authors.lastname: Yamate
authors.forename: Masamichi
authors.initials: M
authors.lastname: Ikawa
authors.forename: Makoto
authors.initials: M
authors.lastname: Yoneda
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Nakajima
authors.forename: Hidetaka
authors.initials: H
authors.lastname: Arishima
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Takeuchi
authors.forename: Kazufumi
authors.initials: K
authors.lastname: Sato
authors.forename: Ken-Ichiro
authors.initials: K
authors.lastname: Kikuta
mesh_terms: D001932:Brain Neoplasms / Q000378:metabolism / Q000473:pathology*; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008223:Lymphoma / Q000378:metabolism / Q000473:pathology*; D008875:Middle Aged