title: CT image quality improvement using Adaptive Iterative Dose Reduction with wide-volume acquisition on 320-detector CT.
abstract: OBJECTIVE
  To evaluate the impact of Adaptive Iterative Dose Reduction (AIDR) on image quality and radiation dose in phantom and patient studies.
  
  
  METHODS
  A phantom was examined in volumetric mode on a 320-detector CT at different tube currents from 25 to 550 mAs. CT images were reconstructed with AIDR and with Filtered Back Projection (FBP) reconstruction algorithm. Image noise, Contrast-to-Noise Ratio (CNR), Signal-to-Noise Ratio (SNR) and spatial resolution were compared between FBP and AIDR images. AIDR was then tested on 15 CT examinations of the lumbar spine in a prospective study. Again, FBP and AIDR images were compared. Image noise and SNR were analysed using a Wilcoxon signed-rank test.
  
  
  RESULTS
  In the phantom, spatial resolution assessment showed no significant difference between FBP and AIDR reconstructions. Image noise was lower with AIDR than with FBP images with a mean reduction of 40%. CNR and SNR were also improved with AIDR. In patients, quantitative and subjective evaluation showed that image noise was significantly lower with AIDR than with FBP. SNR was also greater with AIDR than with FBP.
  
  
  CONCLUSIONS
  Compared to traditional FBP reconstruction techniques, AIDR significantly improves image quality and has the potential to decrease radiation dose.
  
  
  CONCLUSIONS
  This study showed that Adaptive Iterative Dose Reduction (AIDR) reduces image noise.                                                                                                                                                                       In a phantom image noise was reduced without altering spatial resolution.                                                                                                                                                                       In patients AIDR reduced the image noise in lumbar spine CT.                                                                                                                                                                       AIDR can potentially reduce the dose for lumbar spine CT by 52%.
authors.affiliation: Service d'Imagerie Médicale, Hôpital d'Instruction des Armées Legouest, 27 Avenue de Plantières, 57070 Metz, France. alban.gervaise@hotmail.fr
authors.forename: Alban
authors.initials: A
authors.lastname: Gervaise
authors.forename: Benoît
authors.initials: B
authors.lastname: Osemont
authors.forename: Sophie
authors.initials: S
authors.lastname: Lecocq
authors.forename: Alain
authors.initials: A
authors.lastname: Noel
authors.forename: Emilien
authors.initials: E
authors.lastname: Micard
authors.forename: Jacques
authors.initials: J
authors.lastname: Felblinger
authors.forename: Alain
authors.initials: A
authors.lastname: Blum
mesh_terms: D000368:Aged; D000465:Algorithms; D003287:Contrast Media / Q000494:pharmacology; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008159:Lumbar Vertebrae / Q000473:pathology; D008297:Male; D008875:Middle Aged; D019047:Phantoms, Imaging; D010865:Pilot Projects; D011446:Prospective Studies; D011874:Radiometry / Q000379:methods*; D059629:Signal-To-Noise Ratio; D014057:Tomography, X-Ray Computed / Q000379:methods*
chemical_list: D003287:Contrast Media