title: [Efficiency of Cikatridina spray for healing of episiotomy and perineal ruptures].
abstract: Episiotomy is the most common surgical intervention during childbirth. Cikatridina spray allows treatment of this primary contaminated surgical wound and assist its primary healing. The aim of this study is to determine the effectiveness of aid healing of episiotomy, and spontaneous perineal ruptures after normal and operative vaginal delivery.
  
  
  METHODS
  The study included 90 women after spontaneous or operative vaginal delivery with episiotomy or a spontaneous perineal rupture treated with Cikatridina spray. Control group of 90 women was used to compare the efficency. The status of the wound was determined on the first, third, fifth and 30th day after birth, according to presence of the following symptoms: redness, swelling, pain, exudation, epithelization, open wound.
  
  
  RESULTS
  Symptoms of redness, swelling and pain in the group treated with Cikatridina spray after normal birth resolved on the third postpartum day in 100% of cases. Same symptoms after operative vaginal birth persist in average 9% of women and resolved on the 5th day When comparing treated patients with Cikatridina spray with perineal ruptures and the control group in 100% were reported no symptoms in the study group compared with the control group where the redness, swelling persist in 20% and 85.7% epithelization is showing at 5 postpartum day. There was one open episiotomy of a patient from a control group after operative vaginal birth healed in 26 days.
  
  
  CONCLUSIONS
  Cikatridina spray effectively eliminates symptoms of redness, swelling and pain regardless of perineal trauma and the method of delivery. There is an earlier epithelization after using the Cikatridina spray. Open and infected perineal wounds are treated with conventional medicines.
authors.forename: S
authors.initials: S
authors.lastname: Nashar
authors.forename: A
authors.initials: A
authors.lastname: Nikolov
authors.forename: M
authors.initials: M
authors.lastname: Atanasova
authors.forename: T
authors.initials: T
authors.lastname: Garnizov
mesh_terms: D004841:Episiotomy / Q000009:adverse effects*; D005260:Female; D006801:Humans; D009822:Oils, Volatile / Q000627:therapeutic use*; D010502:Perineum / Q000293:injuries* / Q000473:pathology; D010938:Plant Oils / Q000627:therapeutic use; D011247:Pregnancy; D012421:Rupture / Q000188:drug therapy; D012422:Rupture, Spontaneous / Q000188:drug therapy; D014810:Vitamin E / Q000627:therapeutic use*; D014945:Wound Healing / Q000187:drug effects*
chemical_list: C561838:Cikatridina; D009822:Oils, Volatile; D010938:Plant Oils; D014810:Vitamin E