title: Dual kinetically controlled native chemical ligation using a combination of sulfanylproline and sulfanylethylanilide peptide.
abstract: Dual kinetically controlled native chemical ligation using a newly developed sulfanylproline-mediated reaction in combination with an N-sulfanylethylanilide peptide was successfully applied to a previously unreported sequential coupling of peptide fragments added simultaneously to the reaction.
authors.affiliation: Institute of Health Biosciences and Graduate School of Pharmaceutical Sciences, The University of Tokushima, Shomachi, Tokushima 770-8505, Japan.
authors.forename: Hao
authors.initials: H
authors.lastname: Ding
authors.forename: Akira
authors.initials: A
authors.lastname: Shigenaga
authors.forename: Kohei
authors.initials: K
authors.lastname: Sato
authors.forename: Ko
authors.initials: K
authors.lastname: Morishita
authors.forename: Akira
authors.initials: A
authors.lastname: Otaka
mesh_terms: D000595:Amino Acid Sequence; D007700:Kinetics; D015394:Molecular Structure; D009479:Neuropeptides / Q000138:chemical synthesis / Q000737:chemistry*; D010455:Peptides / Q000138:chemical synthesis / Q000737:chemistry*; D013237:Stereoisomerism; D013438:Sulfhydryl Compounds / Q000138:chemical synthesis / Q000737:chemistry*
chemical_list: D009479:Neuropeptides; D010455:Peptides; D013438:Sulfhydryl Compounds; C056900:neuromedin U