title: Usefulness of adjunctive pulse infusion thrombolysis after failed aspiration for massive intracoronary thrombus.
abstract: Slow/no-reflow phenomenon during emergent percutaneous coronary intervention in patients with ST-elevation myocardial infarction (STEMI) results in a poor prognosis. A high thrombus burden was an independent predictor of angiographic slow/no-reflow phenomenon. We experienced a case of a STEMI patient with massive intracoronary thrombus. In our case, a massive red thrombus was aspirated easily by adjunctive pulse infusion thrombolysis (PIT) after failed aspiration. Adjunctive pulse infusion thrombolysis after failed aspiration might be a useful strategy to prevent the slow/no-reflow phenomenon in STEMI patients with massive intracoronary thrombus.
authors.affiliation: Division of Cardiology, Department of Integrated Medicine and Informatics, Ehime University Graduate School of Medicine, and Department of Cardiology, Ehime Prefectural Central Hospital, Ehime, Japan.
authors.forename: Haruhiko
authors.initials: H
authors.lastname: Higashi
authors.forename: Shinji
authors.initials: S
authors.lastname: Inaba
authors.forename: Kazuhisa
authors.initials: K
authors.lastname: Nishimura
authors.forename: Tomoko
authors.initials: T
authors.lastname: Hamagami
authors.forename: Yohei
authors.initials: Y
authors.lastname: Fujita
authors.forename: Akiyoshi
authors.initials: A
authors.lastname: Ogimoto
authors.forename: Hideki
authors.initials: H
authors.lastname: Okayama
authors.forename: Jitsuo
authors.initials: J
authors.lastname: Higaki
mesh_terms: D000368:Aged; D017023:Coronary Angiography; D003328:Coronary Thrombosis / Q000175:diagnosis / Q000628:therapy*; D003331:Coronary Vessels; D004452:Echocardiography; D004562:Electrocardiography; D005260:Female; D005343:Fibrinolytic Agents / Q000008:administration & dosage*; D005500:Follow-Up Studies; D006801:Humans; D007261:Infusions, Intra-Arterial; D012720:Severity of Illness Index; D013396:Suction; D015912:Thrombolytic Therapy / Q000379:methods*; D017211:Treatment Failure
chemical_list: D005343:Fibrinolytic Agents