title: Cord blood adiponectin and infant growth at one year.
abstract: OBJECTIVE
  The aim of this study was to determine the association between cord blood adiponectin and leptin and early infant growth at one year in small for gestational age (SGA) and appropriate for gestational age (AGA) infants.
  
  
  METHODS
  In this prospective study adiponectin and leptin concentrations were determined in cord blood of (i) AGA newborns (n = 44) and (ii) SGA newborns (n = 24). At one year of age, height and weight were measured. Linear regression analysis was used to determine which factors were associated with anthropometric measurements at the age of one year.
  
  
  RESULTS
  (i) SGA neonates had a significantly lower median cord blood adiponectin and leptin than AGA neonates; (ii) among SGA neonates, cord blood adiponectin concentrations were negatively correlated with body weight at one year, weight gain after one year and with BMI at one year; and (iii) among AGA neonates cord blood adiponectin concentrations were negatively correlated with body weight at one year, weight gain after one year and with BMI at one year.
  
  
  CONCLUSIONS
  The disparity in cord blood adiponectin and leptin concentrations between SGA and AGA neonates suggests a role for adipokines in fetal growth.
authors.affiliation: Department of Obstetrics and Gynecology, The Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel-Hashomer, Israel.
authors.forename: Shali
authors.initials: S
authors.lastname: Mazaki-Tovi
authors.forename: Hannah
authors.initials: H
authors.lastname: Kanety
authors.forename: Clara
authors.initials: C
authors.lastname: Pariente
authors.forename: Rina
authors.initials: R
authors.lastname: Hemi
authors.forename: Jacob
authors.initials: J
authors.lastname: Kuint
authors.forename: Yoav
authors.initials: Y
authors.lastname: Yinon
authors.forename: Eyal
authors.initials: E
authors.lastname: Schiff
authors.forename: Eyal
authors.initials: E
authors.lastname: Sivan
mesh_terms: D052242:Adiponectin / Q000097:blood; D001827:Body Height; D015992:Body Mass Index; D001835:Body Weight; D002657:Child Development; D005260:Female; D005312:Fetal Blood / Q000378:metabolism*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007236:Infant, Small for Gestational Age; D020738:Leptin / Q000097:blood; D008297:Male; D011446:Prospective Studies; D015430:Weight Gain
chemical_list: C499918:ADIPOQ protein, human; D052242:Adiponectin; D020738:Leptin