title: Fatigue in chronic dialysis patients.
abstract: Fatigue is common in chronic hemodialysis (HD) patients and impacts on daily living, impairs significantly the quality of life, increases the risk of cardiovascular events and negatively influences survival. Although numerous social, demographic, clinical, and laboratory variables have been associated with fatigue, the causes of this symptom are often unclear. In the absence of an underlying, treatable disorder, the results of therapeutic intervention are typically frustrating. So far, none of the drugs tested can be recommended for preventing and treating fatigue in chronic HD patients. There is some evidence that exercise may significantly improve fatigue in dialysis patients; however, this requires confirmation through large, prospective, randomized studies.
authors.affiliation: Hemodialysis Service, Department of Surgery, Catholic University, Rome, Italy. maubosso@tin.it
authors.forename: Maurizio
authors.initials: M
authors.lastname: Bossola
authors.forename: Carlo
authors.initials: C
authors.lastname: Vulpio
authors.forename: Luigi
authors.initials: L
authors.lastname: Tazza
mesh_terms: D005221:Fatigue / Q000453:epidemiology / Q000209:etiology* / Q000628:therapy; D006801:Humans; D015995:Prevalence; D006435:Renal Dialysis / Q000009:adverse effects*