title: Factors associated with subjective quality of life in Korean patients with depressive disorders: the CRESCEND study.
abstract: OBJECTIVE
  A number of studies suggest that depression is associated with the significant disability and the poorer subjective quality of life (QOL). We aimed to assess subjective QOL in Korean patients with depression and explore the factors (sociodemographic characteristics and clinical features) associated with subjective QOL.
  
  
  METHODS
  We obtained the data from 808 depressive patients who entered the Clinical Research Center for Depression (CRESCEND) study and evaluated the relationship between subjective QOL and personal sociodemographics, and various clinical features, including depressive severity, and subjective QOL. We assessed subjective QOL using the 26-item abbreviated version of the World Health Organization Quality of Life (WHOQOL-BREF) instrument.
  
  
  RESULTS
  Decrements in patients' physical health, psychological health, social relationships, and environment domains of subjective QOL were all strongly associated with the greater depressive symptom severity. After controlling for age and depressive symptom severity, the lower subjective QOL was independently related to being divorced or separated, the less monthly household income, and having no religious practices.
  
  
  CONCLUSIONS
  Our results suggest the importance of sociodemographic characteristics in addition to symptoms for the understanding of subjective QOL in depressed patients. The prospective studies to compare the different treatments' effects on various subjective QOL domains are needed.
authors.affiliation: Department of Psychiatry, The Catholic University College of Medicine, 62 Yeouido-Dong, Youngdeungpo-Gu, Seoul, 150-713, Republic of Korea.
authors.forename: Young-Eun
authors.initials: YE
authors.lastname: Jung
authors.forename: Ho-Jun
authors.initials: HJ
authors.lastname: Seo
authors.forename: Hoo Rim
authors.initials: HR
authors.lastname: Song
authors.forename: Young Sup
authors.initials: YS
authors.lastname: Woo
authors.forename: Hyeon-Woo
authors.initials: HW
authors.lastname: Yim
authors.forename: Hyung-Mo
authors.initials: HM
authors.lastname: Sung
authors.forename: Min-Soo
authors.initials: MS
authors.lastname: Lee
authors.forename: Jae-Min
authors.initials: JM
authors.lastname: Kim
authors.forename: Tae-Youn
authors.initials: TY
authors.lastname: Jun
mesh_terms: D000328:Adult; D003866:Depressive Disorder / Q000150:complications; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011569:Psychiatric Status Rating Scales; D011788:Quality of Life / Q000523:psychology; D056910:Republic of Korea; D012307:Risk Factors; D012959:Socioeconomic Factors; D011795:Surveys and Questionnaires