title: A PROMIS fatigue short form for use by individuals who have multiple sclerosis.
abstract: OBJECTIVE
  To derive from the Patient Reported Outcomes Measurement Information System (PROMIS) fatigue item bank, a short form for individuals with multiple sclerosis (MS), the PROMIS-Fatigue(MS).
  
  
  METHODS
  A panel of 37 clinicians and 46 individuals with MS ranked the relevance of PROMIS fatigue items to persons with MS. Eight items were selected for the PROMIS-Fatigue(MS) that maximized relevance rankings, content coverage, and item discrimination. The PROMIS-Fatigue(MS) and an existing, 7-item PROMIS fatigue short form (PROMIS-Fatigue(SFv1.0)) were administered to a new sample of 231 individuals with MS. Known groups and content validity were assessed.
  
  
  RESULTS
  Scores from the short forms were highly correlated (r = 0.92). Discriminant validity of the PROMIS-Fatigue(MS) scores was supported in known groups comparisons. Scores of neither short form exhibited an advantage in quantitative analyses. The PROMIS-Fatigue(MS) targeted more of the content included in participants' responses to open-ended questions than did the PROMIS-Fatigue(SFv1.0).
  
  
  CONCLUSIONS
  The PROMIS-Fatigue(MS) was derived to have content validity in MS samples. The validity of the measure was further supported by the ability of PROMIS-Fatigue(MS) items to discriminate among groups expected to differ in levels of fatigue. We recommend its use in measuring the fatigue of individuals with MS.
authors.affiliation: Northwestern University, Chicago, IL, USA. karon.cook@northwestern.edu
authors.forename: Karon F
authors.initials: KF
authors.lastname: Cook
authors.forename: Alyssa M
authors.initials: AM
authors.lastname: Bamer
authors.forename: Toni S
authors.initials: TS
authors.lastname: Roddey
authors.forename: George H
authors.initials: GH
authors.lastname: Kraft
authors.forename: Jiseon
authors.initials: J
authors.lastname: Kim
authors.forename: Dagmar
authors.initials: D
authors.lastname: Amtmann
mesh_terms: D000328:Adult; D005221:Fatigue / Q000175:diagnosis* / Q000209:etiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000150:complications*; D017063:Outcome Assessment, Health Care / Q000379:methods*; D011594:Psychometrics; D011788:Quality of Life; D015203:Reproducibility of Results; D011795:Surveys and Questionnaires