title: [Clinical observation of vitrectomy for treatment of diffuse nontraditional diabetic macular edema].
abstract: OBJECTIVE
  To evaluate the efficacy of vitrectomy combined with internal limiting membrane (ILM) peeling in the treatment of diffuse nontraditional diabetic macular edema.
  
  
  METHODS
  It was a retrospective case series study. Clinical records of 21 consecutive patients (21 eyes) with diffuse diabetic macular edema without macular traction were reviewed. All patients underwent pars plana vitrectomy with internal limiting membrane peeling. Main outcome measurements included pre- and postoperative optical coherence tomography (OCT) and visual acuity.
  
  
  RESULTS
  Postoperative follow-up ranged from 12 to 24 months (mean, 16.3 months). Mean preoperative foveal thickness significantly decreased from (406 ± 59) µm to (291 ± 67) µm at 1 months after surgery (t = 9.26, P < 0.01), and further decreased to (280 ± 77) µm at 12 months (t = 9.46, P < 0.01). No differences in visual acuity between preoperative and postoperative were found during follow-up periods. The final best-corrected visual acuity improved in 8 (38.1%) of the 21 eyes, remained unchanged in 11 eyes (52.4%), and decreased in 2 eyes (9.5%).
  
  
  CONCLUSIONS
  Pars plana vitrectomy with internal limiting membrane peeling appears to be beneficial in eyes with diffuse nontraditional diabetic macular edema in retinal thickness but visual acuity outcomes showed only minimal improvement as compared to the baseline.
authors.affiliation: Department of Ophthalmology, Xuanwu Hospital, Capital Medical University, Beijing , China. ldc99@sina.com
authors.forename: Da-chuan
authors.initials: DC
authors.lastname: Liu
authors.forename: Hang
authors.initials: H
authors.lastname: Wu
authors.forename: Hui-qing
authors.initials: HQ
authors.lastname: Yang
mesh_terms: D000328:Adult; D000368:Aged; D048909:Diabetes Complications / Q000601:surgery; D003930:Diabetic Retinopathy / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008269:Macular Edema / Q000209:etiology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D016896:Treatment Outcome; D014821:Vitrectomy / Q000379:methods*