title: Bioactive metabolites from a marine-derived strain of the fungus Neosartorya fischeri.
abstract: Two new compounds named fischeacid and fischexanthone, together with eight known compounds, were obtained from the culture of a marine-derived fungus Neosartorya fischeri strain 1008F₁. The structures of the new compounds were elucidated based on the spectroscopic data. Bioassays indicated that AGI-B4 and 3,4-dihydroxybenzoic acid showed potent inhibitory effect on the replication of tobacco mosaic virus, and AGI-B4 also possessed an inhibition of the cell proliferation of human gastric cancer cell line SGC-7901 and hepatic cancer cells BEL-7404.
authors.affiliation: Institute of Plant Virology, Fujian Agriculture and Forestry University, Fuzhou 350002, Fujian, P.R. China.
authors.forename: Qing-Wei
authors.initials: QW
authors.lastname: Tan
authors.forename: Ming-An
authors.initials: MA
authors.lastname: Ouyang
authors.forename: Shuo
authors.initials: S
authors.lastname: Shen
authors.forename: Wei
authors.initials: W
authors.lastname: Li
mesh_terms: D000970:Antineoplastic Agents / Q000737:chemistry / Q000494:pharmacology; D000998:Antiviral Agents / Q000737:chemistry / Q000494:pharmacology; D045744:Cell Line, Tumor; D049109:Cell Proliferation / Q000187:drug effects; D006801:Humans; D015394:Molecular Structure; D055326:Neosartorya / Q000737:chemistry*; D014027:Tobacco Mosaic Virus / Q000187:drug effects
chemical_list: D000970:Antineoplastic Agents; D000998:Antiviral Agents