title: DDTRP: Database of Drug Targets for Resistant Pathogens.
abstract: Emergence of drug resistance is a major threat to public health. Many pathogens have developed resistance to most of the existing antibiotics, and multidrug-resistant and extensively drug resistant strains are extremely difficult to treat. This has resulted in an urgent need for novel drugs. We describe a database called 'Database of Drug Targets for Resistant Pathogens' (DDTRP). The database contains information on drugs with reported resistance, their respective targets, metabolic pathways involving these targets, and a list of potential alternate targets for seven pathogens. The database can be accessed freely at http://bmi.icmr.org.in/DDTRP.
authors.affiliation: ICMR-Biomedical Informatics Centre, Tuberculosis Research Centre (ICMR), Chetpet, Chennai-600031, Tamil Nadu, India.
authors.forename: Jagadish Chandrabose
authors.initials: JC
authors.lastname: Sundaramurthi
authors.forename: Prabhakaran
authors.initials: P
authors.lastname: Ramanandan
authors.forename: Sridharan
authors.initials: S
authors.lastname: Brindha
authors.forename: Chelladurai Ramarathnam
authors.initials: CR
authors.lastname: Subhasree
authors.forename: Abhimanyu
authors.initials: A
authors.lastname: Prasad
authors.forename: Vasanthapuram
authors.initials: V
authors.lastname: Kumaraswami
authors.forename: Luke Elizabeth
authors.initials: LE
authors.lastname: Hanna