title: Invasive infection in an acute myeloblastic leukemia patient due to triazole-resistant Candida tropicalis.
abstract: Non-albicans Candida species are being increasingly reported as causes of nosocomial fungal infections. For example, invasive candidiasis caused by C. tropicalis has been associated with hematologic malignancies. In this study, we report a fatal case of fungemia and a possible urinary and pulmonary infection in a leukemia patient that was due to a strain of C. tropicalis resistant to 2 triazole antifungals.
authors.affiliation: Departamento de Micologia, Centro de Ciências Biológicas, Universidade Federal de Pernambuco, Av. Prof. Nelson Chaves, s/no- Cidade Universitária, 50670-420 Recife, Brazil.
authors.forename: Ana Maria Rabelo
authors.initials: AM
authors.lastname: de Carvalho Parahym
authors.forename: Carolina Maria
authors.initials: CM
authors.lastname: da Silva
authors.forename: Mariele Porto Carneiro
authors.initials: MP
authors.lastname: Leão
authors.forename: Michele Chianca
authors.initials: MC
authors.lastname: Macario
authors.forename: Gustavo Antônio da Trindade Meira Henriques
authors.initials: GA
authors.lastname: Filho
authors.forename: Neiva Tinti
authors.initials: NT
authors.lastname: de Oliveira
authors.forename: Rejane Pereira
authors.initials: RP
authors.lastname: Neves
mesh_terms: D000368:Aged; D000935:Antifungal Agents / Q000494:pharmacology / Q000627:therapeutic use*; D041022:Candida tropicalis / Q000187:drug effects* / Q000302:isolation & purification; D002177:Candidiasis / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D025141:Drug Resistance, Fungal; D017809:Fatal Outcome; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000150:complications*; D008297:Male; D008826:Microbial Sensitivity Tests; D012772:Shock, Septic / Q000150:complications; D014230:Triazoles / Q000494:pharmacology / Q000627:therapeutic use*
chemical_list: D000935:Antifungal Agents; D014230:Triazoles