title: Trends in poisoning hospitalization and mortality in Taiwan, 1999-2008: a retrospective analysis.
abstract: BACKGROUND
  Subjects with non-fatal poisoning may be left with permanent, disabling sequelae, and the resultant long-term use of medical services smay be a burden on the public health care system. The objective of this study was to describe the epidemiology of poisoning in Taiwan from 1999 to 2008.
  
  
  METHODS
  We analyzed poisoning-related data of mortality rates sourced from official Taiwanese vital statistics and of hospitalization from the National Health Insurance (NHI) Research Database. The data were age-adjusted to the year 2000 Standard Population to determine 10-year hospitalization and mortality rate trends, which we stratified according to gender, age, and poisoning agent. Poisson regression was used to investigate the trends.
  
  
  RESULTS
  There were 20,260 deaths and 210,021 hospitalizations related to poisoning, with mortality and hospitalization rates of 8.21 per 100,000 and 86.30 per 100,000 population, respectively. Males exhibited higher rates of mortality and hospitalization as a result of poisoning, with the highest risk in those aged 65 years or older. Medicinal drugs followed by pesticides were the two most common agents of poisoning. There was an increasing trend of both poisoning-related mortality and hospitalization rates during the study period, with a greater increase occurring in the hospitalization rate than in the mortality rate.
  
  
  CONCLUSIONS
  We found the males aged 65 years or older were at highest risk of poisoning, with medicinal drugs being the leading cause. Hospitalization rates increased more than mortality rates over the 10-year period. Appropriate poisoning prevention programs need to be developed. We should strengthen case management and improve access to health services to increase survival in cases of poisoning.
authors.affiliation: School of Public Health, National Defense Medical Center, No, 161, Section 6, Min-Chuan E, Rd,, Neihu, Taipei, 11490, Taiwan. chienwu@mail.ndmctsgh.edu.tw
authors.forename: Wu-Chien
authors.initials: WC
authors.lastname: Chien
authors.forename: Jin-Ding
authors.initials: JD
authors.lastname: Lin
authors.forename: Ching-Huang
authors.initials: CH
authors.lastname: Lai
authors.forename: Chi-Hsiang
authors.initials: CH
authors.lastname: Chung
authors.forename: Yu-Chen
authors.initials: YC
authors.lastname: Hung
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006760:Hospitalization / Q000639:trends*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011041:Poisoning / Q000401:mortality*; D012189:Retrospective Studies; D012737:Sex Factors; D013624:Taiwan / Q000453:epidemiology; D055815:Young Adult