title: A new shield for a cytokine storm.
abstract: Highly virulent influenza virus infection results in excessive cytokine production, recruitment of leukocytes, and immune-mediated pulmonary injury. Teijaro et al. (2011) now demonstrate that sphingosine-1-phosphate receptor 1 ligands suppress all features of flu-inflicted pathological inflammation and place the endothelium at the center of this regulatory network.
authors.affiliation: Department of Immunobiology, School of Medicine, Yale University New Haven, CT 06520, USA.
authors.forename: Akiko
authors.initials: A
authors.lastname: Iwasaki
authors.forename: Ruslan
authors.initials: R
authors.lastname: Medzhitov