title: Analysis of crown widths in subjects with congenitally missing maxillary lateral incisors.
abstract: The aim of the study was to test the hypothesis that the gene defect causing congenital absence of maxillary lateral incisors also causes narrowing of the dentition. A total of 81 patients with one or two congenitally missing lateral incisors were retrieved; 52 (64.2 per cent) patients presented bilateral agenesis, whereas 29 (35.8 per cent) had unilateral agenesis. The control group consisted of 90 consecutively treated patients. The largest mesiodistal crown dimension for all teeth, except for the maxillary second and third molars, was measured on plaster casts using a digital caliper to the nearest 10th of a millimetre. Statistical testing was performed using the analysis of variance model (P < 0.05) to test for differences in the mesiodistal dimension between the sample and the control group. Significance has been assessed using a P-value threshold level of 5 per cent. Agenesis of maxillary lateral incisors was found to be a significant predictor of tooth size. Patients who were missing maxillary lateral incisors had smaller teeth compared to control subjects, except for the maxillary right and left first molars. This finding was true for both unilateral and bilateral lateral incisor agenesis. Interaction between maxillary lateral incisor agenesis and gender was not significant. Patients with congenitally missing lateral incisors have narrower teeth than patients without any dental anomalies, except for maxillary first molars. A higher prevalence of microdontic contralateral incisors was found in patients with unilateral agenesis with respect to the control group.
authors.affiliation: Department of Orthodontics, University of Ferrara, Italy. davidemirabella@hotmail.com
authors.forename: A Davide
authors.initials: AD
authors.lastname: Mirabella
authors.forename: Vincent G
authors.initials: VG
authors.lastname: Kokich
authors.forename: Marco
authors.initials: M
authors.lastname: Rosa
mesh_terms: D000293:Adolescent; D000704:Analysis of Variance; D000848:Anodontia / Q000453:epidemiology / Q000235:genetics*; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D007180:Incisor / Q000002:abnormalities*; D008297:Male; D008437:Maxilla; D008963:Molar / Q000033:anatomy & histology; D008964:Molar, Third / Q000033:anatomy & histology; D019228:Tooth Crown / Q000473:pathology*; D055815:Young Adult