title: Practical radical cyclizations with arylboronic acids and trifluoroborates.
abstract: Practical radical cyclizations using organoboronic acids and trifluoroborates take place in water, open to air, and in a scalable fashion employing catalytic silver nitrate and stoichiometric potassium persulfate. Both Pschorr-type cyclizations and tandem radical cyclization/trap cascades are described, illustrating the utility of these mild conditions for the generation of polycyclic scaffolds.
authors.affiliation: Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA.
authors.forename: Jonathan W
authors.initials: JW
authors.lastname: Lockner
authors.forename: Darryl D
authors.initials: DD
authors.lastname: Dixon
authors.forename: Rune
authors.initials: R
authors.lastname: Risgaard
authors.forename: Phil S
authors.initials: PS
authors.lastname: Baran
mesh_terms: D001881:Borates / Q000737:chemistry*; D001897:Boronic Acids / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D006845:Hydrocarbons, Fluorinated / Q000737:chemistry*; D015394:Molecular Structure; D011084:Polycyclic Aromatic Hydrocarbons / Q000138:chemical synthesis* / Q000737:chemistry; D014867:Water / Q000737:chemistry
chemical_list: D001881:Borates; D001897:Boronic Acids; D006845:Hydrocarbons, Fluorinated; D011084:Polycyclic Aromatic Hydrocarbons; D014867:Water