title: [Research progress of BDNF and depression].
abstract: BDNF is widespread existed in CNS and PNS, because of its function in nerve regeneration and restoration, more and more researches focused on the effect of BDNF on neural plasticity in the development of depression and the mechanisms of antidepressant. This article review the basic results and the research trends on BDNF and depression at present, more researches about the interactions of BDNF and proBDNF, BDNF and other transmitters and their receptors should be expected.
authors.affiliation: College of Life Science, Shanxi Normal University, Xian 710062, China.
authors.forename: Hui
authors.initials: H
authors.lastname: Qiao
authors.forename: Shu-Cheng
authors.initials: SC
authors.lastname: An
authors.forename: Chang
authors.initials: C
authors.lastname: Xu
mesh_terms: D000818:Animals; D000928:Antidepressive Agents / Q000494:pharmacology*; D001921:Brain / Q000378:metabolism / Q000502:physiology; D019208:Brain-Derived Neurotrophic Factor / Q000378:metabolism / Q000502:physiology*; D003863:Depression / Q000503:physiopathology*; D006801:Humans; D009473:Neuronal Plasticity / Q000502:physiology*; D020813:Receptor, trkB / Q000378:metabolism
chemical_list: D000928:Antidepressive Agents; D019208:Brain-Derived Neurotrophic Factor; D020813:Receptor, trkB