title: Targeting histone lysine demethylases by truncating the histone 3 tail to obtain selective substrate-based inhibitors.
authors.affiliation: Department of Medicinal Chemistry, Faculty of Pharmaceutical Sciences, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen, Denmark.
authors.forename: Brian
authors.initials: B
authors.lastname: Lohse
authors.forename: Anders L
authors.initials: AL
authors.lastname: Nielsen
authors.forename: Jan B L
authors.initials: JB
authors.lastname: Kristensen
authors.forename: Charlotte
authors.initials: C
authors.lastname: Helgstrand
authors.forename: Paul A C
authors.initials: PA
authors.lastname: Cloos
authors.forename: Lars
authors.initials: L
authors.lastname: Olsen
authors.forename: Michael
authors.initials: M
authors.lastname: Gajhede
authors.forename: Rasmus P
authors.initials: RP
authors.lastname: Clausen
authors.forename: Jesper L
authors.initials: JL
authors.lastname: Kristensen
mesh_terms: D000595:Amino Acid Sequence; D055162:Biocatalysis; D004791:Enzyme Inhibitors / Q000737:chemistry* / Q000494:pharmacology; D056466:Histone Demethylases / Q000037:antagonists & inhibitors* / Q000378:metabolism; D006657:Histones / Q000737:chemistry* / Q000378:metabolism; D006801:Humans; D056484:Jumonji Domain-Containing Histone Demethylases / Q000037:antagonists & inhibitors / Q000378:metabolism; D008969:Molecular Sequence Data; D013379:Substrate Specificity; D014157:Transcription Factors / Q000037:antagonists & inhibitors / Q000378:metabolism
chemical_list: D004791:Enzyme Inhibitors; D006657:Histones; C413655:KDM4C protein, human; D014157:Transcription Factors; D056466:Histone Demethylases; D056484:Jumonji Domain-Containing Histone Demethylases; C511934:PHF8 protein, human; C494424:KDM4A protein, human