title: Sporobolomyces roseus in the cerebrospinal fluid of an immunocompetent patient--to treat or not to treat?
abstract: We present the case of an immunocompetent male who presented with symptoms of meningitis. Yeasts were seen in two consecutive cerebrospinal fluid samples, which were identified by PCR as Sporobolomyces roseus. This yeast is rarely encountered in clinical settings, and has only previously been seen to cause infection in immunocompromised patients. This case highlights the challenges presented by the identification of an unusual pathogen in an unexpected clinical setting.
authors.affiliation: Department of Microbiology, Beaumont Hospital, Dublin 9, Ireland.|Department of Clinical Microbiology, Royal College of Surgeons in Ireland, Dublin 9, Ireland.
authors.forename: S
authors.initials: S
authors.lastname: McNicholas
authors.affiliation: Department of Microbiology, Beaumont Hospital, Dublin 9, Ireland.
authors.forename: H
authors.initials: H
authors.lastname: McDermott
authors.affiliation: Department of Microbiology, Beaumont Hospital, Dublin 9, Ireland.
authors.forename: L
authors.initials: L
authors.lastname: Power
authors.affiliation: Mycology Reference Laboratory, Southwest HPA Laboratory, Myrtle Road, Kingsdown, Bristol, UK.
authors.forename: E M
authors.initials: EM
authors.lastname: Johnson
authors.affiliation: Department of Neurology, Beaumont Hospital, Dublin 9, Ireland.
authors.forename: J
authors.initials: J
authors.lastname: Moroney
authors.affiliation: Department of Microbiology, Beaumont Hospital, Dublin 9, Ireland.|Department of Clinical Microbiology, Royal College of Surgeons in Ireland, Dublin 9, Ireland.
authors.forename: H
authors.initials: H
authors.lastname: Humphreys
authors.affiliation: Department of Microbiology, Beaumont Hospital, Dublin 9, Ireland.
authors.forename: E G
authors.initials: EG
authors.lastname: Smyth
mesh_terms: D000328:Adult; D000666:Amphotericin B / Q000008:administration & dosage; D000935:Antifungal Agents / Q000008:administration & dosage; D001487:Basidiomycota / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D020314:Central Nervous System Fungal Infections / Q000175:diagnosis* / Q000188:drug therapy; D002555:Cerebrospinal Fluid / Q000382:microbiology*; D004271:DNA, Fungal / Q000235:genetics; D006801:Humans; D008297:Male; D008581:Meningitis / Q000175:diagnosis* / Q000382:microbiology*; D016133:Polymerase Chain Reaction
chemical_list: D000935:Antifungal Agents; D004271:DNA, Fungal; C068538:liposomal amphotericin B; D000666:Amphotericin B