title: FLUKA simulations of the response of tissue-equivalent proportional counters to ion beams for applications in hadron therapy and space.
abstract: For both cancer therapy with protons and ions (hadron therapy) and space radiation environments, the spatial energy deposition patterns of the radiation fields are of importance for quantifying the resulting radiation damage in biological structures. Tissue-equivalent proportional counters (TEPC) are the principal instruments for measuring imparted energy on a microscopic scale and for characterizing energy deposition patterns of radiation. Moreover, the distribution of imparted energy can serve as a complementary quantity to particle fluences of the primary beam and secondary fragments for characterizing a radiation field on a physical basis for radiobiological models. In this work, the Monte Carlo particle transport code FLUKA is used for simulating energy depositions in TEPC by ion beams. The capability of FLUKA in predicting imparted energy and derived quantities, such as lineal energy, for microscopic volumes is evaluated by comparing it with a large set of TEPC measurements for different ion beams with atomic numbers ranging from 1 to 26 and energies from 80 up to 1000 MeV/n. The influence of different physics configurations in the simulation is also discussed. It is demonstrated that FLUKA can simulate energy deposition patterns of ions in TEPC cavities accurately and that it provides an adequate description of the main features of the spectra.
authors.affiliation: European Organization for Nuclear Research CERN, CH-1211, Geneva 23, Switzerland. Till.Tobias.Boehlen@cern.ch
authors.forename: T T
authors.initials: TT
authors.lastname: Böhlen
authors.forename: M
authors.initials: M
authors.lastname: Dosanjh
authors.forename: A
authors.initials: A
authors.lastname: Ferrari
authors.forename: I
authors.initials: I
authors.lastname: Gudowska
authors.forename: A
authors.initials: A
authors.lastname: Mairani
mesh_terms: D007477:Ions / Q000627:therapeutic use; D008962:Models, Theoretical; D009010:Monte Carlo Method; D061766:Proton Therapy; D011878:Radiotherapy / Q000295:instrumentation*; D011879:Radiotherapy Dosage
chemical_list: D007477:Ions