title: [Clinical course and outcomes of influenza A (H1N1) 2009 in pregnant women].
abstract: OBJECTIVE
  Study of course of pregnancy, delivery, postpartum period and perinatal outcomes in pregnant women with influenza A (H1N1) 2009.
  
  
  METHODS
  Course of pregnancy and outcomes in 16 women, who had influenza A (H1N1) 2009, were analyzed. Influenza A (H1N1) 2009 virus was detected by PCR.
  
  
  RESULTS
  Influenza A (H1N1) 2009 had a severe course and high rates of complications: pneumonia (100%), respiratory distress syndrome (25%), placental deficiency (100%). Most of the neonates (87%) from mothers, who had influenza A (H1N1) 2009, had neonatal period disorders: congenital pneumonia--2 (12.5%), cerebral ischemia--10 (62.5%), hyperbilirubinemia--2 (12.5%), vegeto-visceral syndrome--4 (25%), hemorrhagic, convulsive and respiratory distress syndrome--1 (6.7%) each. Alteration in placenta was detected--influenza placentitis. Transplacental route of virus transmission was not detected.
  
  
  CONCLUSIONS
  Pregnant women are a high risk group for influenza and serious complications caused by the virus. Influenza A (H1N1) 2009 has a more severe course and a higher rate of complications in both mothers and neonates.
authors.forename: D A
authors.initials: DA
authors.lastname: Tarbaeva
authors.forename: M P
authors.initials: MP
authors.lastname: Kostinov
authors.forename: S A
authors.initials: SA
authors.lastname: Iozefson
authors.forename: E D
authors.initials: ED
authors.lastname: Zagorodnyaya
mesh_terms: D000293:Adolescent; D000328:Adult; D002545:Brain Ischemia / Q000453:epidemiology / Q000209:etiology; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D053118:Influenza A Virus, H1N1 Subtype; D007251:Influenza, Human / Q000150:complications* / Q000453:epidemiology / Q000503:physiopathology*; D010922:Placenta Diseases / Q000453:epidemiology / Q000821:virology; D011014:Pneumonia / Q000453:epidemiology / Q000821:virology; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000453:epidemiology / Q000503:physiopathology* / Q000821:virology*; D012128:Respiratory Distress Syndrome / Q000453:epidemiology / Q000821:virology; D012127:Respiratory Distress Syndrome, Newborn / Q000453:epidemiology / Q000821:virology; D016896:Treatment Outcome