title: Epidemic methicillin-susceptible Staphylococcus aureus lineages are the main cause of infections at an Iranian university hospital.
abstract: The majority of Staphylococcus aureus infections from Isfahan, Iran, were caused by epidemic methicillin-susceptible S. aureus (MSSA) lineages, sequence type 8 (ST8), ST22, ST30, and ST6. The predominant methicillin-resistant S. aureus strain was ST239. We observed a high prevalence of Panton-Valentine leukocidin-positive MSSA strains (19.7%), which is a matter of considerable concern, since these strains have the ability to cause severe infections.
authors.affiliation: Isfahan University of Medical Sciences, Isfahan, Iran.
authors.forename: Seyed Asghar
authors.initials: SA
authors.lastname: Havaei
authors.forename: Sinisa
authors.initials: S
authors.lastname: Vidovic
authors.forename: Narimani
authors.initials: N
authors.lastname: Tahmineh
authors.forename: Kazemi
authors.initials: K
authors.lastname: Mohammad
authors.forename: Karbalaei
authors.initials: K
authors.lastname: Mohsen
authors.forename: Stefania
authors.initials: S
authors.lastname: Starnino
authors.forename: Jo-Anne R
authors.initials: JA
authors.lastname: Dillon
mesh_terms: D000483:Alleles; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001427:Bacterial Toxins / Q000235:genetics; D016000:Cluster Analysis; D004269:DNA, Bacterial / Q000737:chemistry / Q000235:genetics; D005098:Exotoxins / Q000235:genetics; D005838:Genotype; D006785:Hospitals, University; D006801:Humans; D007492:Iran / Q000453:epidemiology; D007956:Leukocidins / Q000235:genetics; D008712:Methicillin / Q000494:pharmacology*; D008969:Molecular Sequence Data; D058889:Molecular Typing; D010802:Phylogeny; D017422:Sequence Analysis, DNA; D013203:Staphylococcal Infections / Q000453:epidemiology* / Q000382:microbiology; D013211:Staphylococcus aureus / Q000145:classification* / Q000187:drug effects / Q000235:genetics / Q000302:isolation & purification*
chemical_list: D000900:Anti-Bacterial Agents; D001427:Bacterial Toxins; D004269:DNA, Bacterial; D005098:Exotoxins; D007956:Leukocidins; C078284:Panton-Valentine leukocidin; D008712:Methicillin