title: [Research progress in regulation of adiponectin receptors expression].
abstract: Adiponectin is an adipokine mainly secreted by adipose tissue, which exerts insulin-sensitivity, anti-inflammation, anti-atherosclerosis and cardio-protective effects. These biological effects are mediated by adiponectin receptor 1 and adiponectin receptor 2. Expression levels of adiponectin receptor affect activation of downstream signaling pathway and biological effects. Research about regulation factors of adiponectin receptor expression contributes discovering the molecular mechanism and provides new ideas for the prevention and treatment of the metabolism disorder and cardiovascular diseases.
authors.affiliation: Department of Physiology and Pathophysiology, Peking University Health Science Center, Key Laboratory of Molecular Cardiovascular Science, Ministry of Education, Beijing 100191, China.
authors.forename: Xiao-Bing
authors.initials: XB
authors.lastname: Cui
authors.forename: Yi
authors.initials: Y
authors.lastname: Han
authors.forename: Li
authors.initials: L
authors.lastname: Li
authors.forename: Li-Ling
authors.initials: LL
authors.lastname: Wu
mesh_terms: D051700:Activating Transcription Factor 3 / Q000378:metabolism; D052242:Adiponectin / Q000502:physiology*; D000818:Animals; D000071161:Forkhead Box Protein O1; D051858:Forkhead Transcription Factors / Q000378:metabolism; D006801:Humans; D008869:Microtubule-Associated Proteins / Q000378:metabolism; D009687:Nuclear Proteins / Q000378:metabolism; D019869:Phosphatidylinositol 3-Kinases / Q000378:metabolism; D054419:Receptors, Adiponectin / Q000378:metabolism / Q000502:physiology*
chemical_list: D051700:Activating Transcription Factor 3; D052242:Adiponectin; D000071161:Forkhead Box Protein O1; D051858:Forkhead Transcription Factors; D008869:Microtubule-Associated Proteins; D009687:Nuclear Proteins; D019869:Phosphatidylinositol 3-Kinases; D054419:Receptors, Adiponectin; C085126:FOXO1 protein, human; C476755:NINL protein, human