title: Pregnane derivatives from Potentilla evestita.
abstract: A new pregnane derivative, 2,6beta,7beta-trihydroxy-4-methyl-19-norpregna-1,3,5(10)-trien-17-one, has been isolated from the ethyl acetate soluble fraction of Potentilla evestita along with a pregnane derivative, 11alpha,17alpha,21-trihydroxypregna-4,16(22)-diene-3,20-dione, that is reported for the first time as a natural product. Their structures were elucidated with the aid of 1H and 13C NMR spectra and by COSY, HMQC, HMBC and NOESY experiments.
authors.affiliation: International Center for Chemical and Biological Sciences, HEJ Research Institute of Chemistry, University of Karachi, Karachi - 75270, Pakistan.
authors.forename: Rehan
authors.initials: R
authors.lastname: Khan
authors.forename: Farah
authors.initials: F
authors.lastname: Siddiq
authors.forename: Itrat
authors.initials: I
authors.lastname: Fatima
authors.forename: Shazia
authors.initials: S
authors.lastname: Yasmeen
authors.forename: Aman
authors.initials: A
authors.lastname: Karim
authors.forename: Abdul
authors.initials: A
authors.lastname: Malik
authors.forename: Nighat
authors.initials: N
authors.lastname: Afza
authors.forename: Saira
authors.initials: S
authors.lastname: Hameed
mesh_terms: D015394:Molecular Structure; D031987:Potentilla / Q000737:chemistry*; D011278:Pregnanes / Q000737:chemistry*
chemical_list: C561790:11alpha,17alpha,21-trihydroxypregna-4,16(22)-diene-3,20-dione; C561789:2,6beta,7beta-trihydroxy-4-methyl-19-norpregna-1,3,5(10)-trien-17-one; D011278:Pregnanes