title: Topical therapy of hand eczema - analysis of the prescription profile from dermatologists in private practice.
abstract: BACKGROUND
  Chronic hand eczema (CHE) is a common dermatological disease. Due to different etiologies, severity levels, and high therapy costs, it presents a challenge for dermatologists. Nowadays, it is recommended that treatment be adapted to the severity of the disease. According to the guidelines on the management of hand eczema, topical corticosteroids are the first-line therapy for hand eczema.
  
  
  METHODS
  The present study investigated the prescription profile of topical treatments. Data sets from 13 191 patients with hand eczema were analyzed.
  
  
  RESULTS
  The results indicate that topical corticosteroids are frequently prescribed for the treatment of hand eczema. Corticosteroid treatment (72.6 %) was most commonly prescribed by private practice physicians. Betamethasone was the most frequently prescribed, but other substances such as mometasone furoate, prednicarbate, clobetasol, and methylprednisolone aceponate were often prescribed as well.
  
  
  CONCLUSIONS
  The results show that the concept of the risk-to-benefit ratio is reflected by the prescription profile of topical corticosteroids (therapeutic index). However, even corticosteroids with a less favorable therapeutic index are sometimes prescribed, perhaps due to economic reasons.
authors.affiliation: Department of Dermatology, Venereology and Allergology, Charité Universitätsmedizin Berlin, Germany             IMS Health GmbH & Co. OHG, Frankfurt, Germany.
authors.forename: Stephanie
authors.initials: S
authors.lastname: Soost
authors.forename: Mandana
authors.initials: M
authors.lastname: Abdollahnia
authors.forename: Karel
authors.initials: K
authors.lastname: Kostev
authors.forename: Margitta
authors.initials: M
authors.lastname: Worm
mesh_terms: D000287:Administration, Topical; D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000008:administration & dosage*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D003880:Dermatology / Q000706:statistics & numerical data*; D004485:Eczema / Q000188:drug therapy* / Q000453:epidemiology; D005260:Female; D005858:Germany / Q000453:epidemiology; D006229:Hand Dermatoses / Q000188:drug therapy* / Q000453:epidemiology; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D010818:Practice Patterns, Physicians' / Q000706:statistics & numerical data; D055656:Prescriptions / Q000706:statistics & numerical data*; D015995:Prevalence; D011331:Private Practice / Q000706:statistics & numerical data*; D055815:Young Adult
chemical_list: D000305:Adrenal Cortex Hormones