title: Damage control: how HIV survives the editor APOBEC3G.
abstract: The antiviral factor APOBEC3G upregulates the expression of ligands for the activating receptor NKG2D via DNA damage induced by the viral protein Vpr in cells infected with human immunodeficiency virus. The virus overcomes greater susceptibility to natural killer cell–mediated lysis by targeting APOBEC3G for degradation.
authors.forename: J Ludovic
authors.initials: JL
authors.lastname: Croxford
authors.forename: Stephan
authors.initials: S
authors.lastname: Gasser
mesh_terms: D000071480:APOBEC-3G Deaminase; D003564:Cytidine Deaminase / Q000502:physiology*; D006678:HIV / Q000276:immunology*; D006801:Humans; D007694:Killer Cells, Natural / Q000276:immunology*; D013601:T-Lymphocytes / Q000821:virology*
chemical_list: D000071480:APOBEC-3G Deaminase; C464924:APOBEC3G protein, human; D003564:Cytidine Deaminase