title: Scientific frontiers: emerging technologies for salivary diagnostics.
abstract: Saliva, a biofluid historically well-studied biochemically and physiologically, has entered the post-genomic 'omics' era, where its proteomic, genomic, and microbiome constituents have been comprehensively deciphered. The translational path of these salivary constituents has begun toward a variety of personalized individual medical applications, including early detection of cancer. Salivary diagnostics is a late-comer, but it is catching up where dedicated resources, like the Salivaomics Knowledge Base (SKB), now have taken center stage in the dissemination of the diagnostic potentials of salivary biomarkers and other translational and clinical utilities.
authors.affiliation: Molecular Physiology and Therapeutics Branch, NIDCR, NIH, Bethesda, MD 20892, USA.
authors.forename: B J
authors.initials: BJ
authors.lastname: Baum
authors.forename: J R
authors.initials: JR
authors.lastname: Yates
authors.forename: S
authors.initials: S
authors.lastname: Srivastava
authors.forename: D T W
authors.initials: DT
authors.lastname: Wong
authors.forename: J E
authors.initials: JE
authors.lastname: Melvin
mesh_terms: D014408:Biomarkers, Tumor; D003945:Diagnosis, Oral / Q000379:methods*; D055088:Early Detection of Cancer; D006801:Humans; D051188:Knowledge Bases; D054892:Metagenome; D040901:Proteomics; D012463:Saliva / Q000737:chemistry / Q000502:physiology; D012471:Salivary Proteins and Peptides
chemical_list: D014408:Biomarkers, Tumor; D012471:Salivary Proteins and Peptides