title: [Dynamics of blood concentration of neurospecific proteins and risk of neuropathy development in the conditions of 105-day confinement].
abstract: Six male volunteers (aged 25 to 40 years) were subjects in all-round psychophysiological, hormonal and immunological studies before, in and after 105-day isolation and confinement. Blood was drawn and the 16-factorial Cattell personality inventory was filled out every 30 days. Concentrations of blood hormones, neurospecific proteins and cytokines point to a close interrelation between antibody titers to myelin-associated glycoprotein and changes in the parameters of metabolism and reproduction-related hormones, as well as cytokines and individual psychophysiology (extra-introversion, dominance, intropunitiveness, social contact selectivity, etc.), and suggest a minimum risk of demyelinizing neuropathy due to exposure to the conditions of isolation and confinement.
authors.forename: I A
authors.initials: IA
authors.lastname: Nichiporuk
authors.forename: G Iu
authors.initials: GIu
authors.lastname: Vasil'eva
authors.forename: M P
authors.initials: MP
authors.lastname: Rykova
authors.forename: B V
authors.initials: BV
authors.lastname: Morukov
mesh_terms: D000328:Adult; D000906:Antibodies / Q000097:blood / Q000276:immunology; D016207:Cytokines / Q000096:biosynthesis / Q000097:blood; D003711:Demyelinating Diseases / Q000097:blood* / Q000175:diagnosis / Q000276:immunology* / Q000517:prevention & control; D006728:Hormones / Q000096:biosynthesis / Q000097:blood; D006801:Humans; D007120:Immunochemistry; D008297:Male; D018992:Myelin-Associated Glycoprotein / Q000096:biosynthesis* / Q000097:blood; D011115:Polyneuropathies / Q000097:blood* / Q000175:diagnosis / Q000276:immunology* / Q000517:prevention & control; D012044:Regression Analysis; D012307:Risk Factors; D012919:Social Behavior; D012934:Social Isolation / Q000523:psychology*; D013026:Space Flight; D018561:Space Simulation / Q000379:methods*; D011795:Surveys and Questionnaires
chemical_list: D000906:Antibodies; D016207:Cytokines; D006728:Hormones; D018992:Myelin-Associated Glycoprotein