title: Heterogeneity in simvastatin-induced cytotoxicity in AML is caused by differences in Ras-isoprenylation.
authors.forename: K
authors.initials: K
authors.lastname: van der Weide
authors.forename: P M
authors.initials: PM
authors.lastname: Korthuis
authors.forename: F
authors.initials: F
authors.lastname: Kuipers
authors.forename: E G E
authors.initials: EG
authors.lastname: de Vries
authors.forename: E
authors.initials: E
authors.lastname: Vellenga
mesh_terms: D002070:Butadienes / Q000494:pharmacology; D048049:Extracellular Signal-Regulated MAP Kinases / Q000378:metabolism; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000494:pharmacology*; D015470:Leukemia, Myeloid, Acute / Q000188:drug therapy* / Q000378:metabolism; D009570:Nitriles / Q000494:pharmacology; D054876:Prenylation / Q000187:drug effects*; D019821:Simvastatin / Q000494:pharmacology*; D018631:ras Proteins / Q000378:metabolism*
chemical_list: D002070:Butadienes; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D009570:Nitriles; C113580:U 0126; D019821:Simvastatin; D048049:Extracellular Signal-Regulated MAP Kinases; D018631:ras Proteins