title: Analgesic and anti-inflammatory properties of Thespesia populnea leaf extracts.
abstract: Analgesic and anti-inflammatory activities of the aqueous and ethanol extracts of Thespesia populnea Soland. ex. Correa (Malvaceae) leaves were evaluated in animal models. Orally-administered aqueous and ethanol extracts (100, 200 and 400 mg kg⁻¹ bw) showed significant analgesic activity in chemical-, mechanical- and thermally-induced pain test models in mice. The extracts also reduced paw oedema induced by carrageenan in rats. The results obtained in this study suggest that Thespesia populnea extracts have analgesic and anti-inflammatory properties.
authors.affiliation: Department of Pharmacology, C.L. Baid Metha College of Pharmacy, Thorapakkam, Chennai-600096, India. arilavarasan@yahoo.co.in
authors.forename: R
authors.initials: R
authors.lastname: Ilavarasan
authors.forename: S
authors.initials: S
authors.lastname: Mohideen
authors.forename: S
authors.initials: S
authors.lastname: Venkataraman
mesh_terms: D000700:Analgesics / Q000737:chemistry / Q000627:therapeutic use*; D000818:Animals; D000893:Anti-Inflammatory Agents / Q000737:chemistry / Q000627:therapeutic use*; D002351:Carrageenan / Q000494:pharmacology; D004487:Edema / Q000139:chemically induced / Q000188:drug therapy; D019660:Malvaceae / Q000737:chemistry*; D010146:Pain / Q000188:drug therapy; D010936:Plant Extracts / Q000737:chemistry / Q000627:therapeutic use*; D018515:Plant Leaves / Q000737:chemistry*; D051381:Rats
chemical_list: D000700:Analgesics; D000893:Anti-Inflammatory Agents; D010936:Plant Extracts; D002351:Carrageenan