title: The effects of serotonin transporter promoter and monoamine oxidase A gene polymorphisms on trait emotional intelligence.
abstract: OBJECTIVE
  The purpose of this study was to evaluate the influences of major serotonin-related genetic variants of the serotonin transporter-linked promoter region (5-HTTLPR), tryptophan hydroxylase 1 gene (TPH1) and monoamine oxidase A gene (MAOA-EcoRV) on trait emotional intelligence (EI).
  
  
  METHODS
  The Trait Meta-Mood Scale (TMMS) measuring trait EI and genotyping were performed in 336 healthy Korean college students (204 males, 132 females).
  
  
  RESULTS
  Among the male participants, those with the T genotype of MAOA (lower MAOA activity) had significantly lower subscale scores on the TMMS than those with the C genotype (higher MAOA activity) did. Additionally, male participants with the s/s genotype of the 5-HTTLPR gene had significantly lower attention subscale scores and total TMMS scores than those with the non-s/s (l/l + l/s) genotypes did. Among the female participants, there were no associations between any of the 5-HTTLPR, TPH1 or MAOA-EcoRV polymorphisms and any of the TMMS scores.
  
  
  CONCLUSIONS
  These findings suggest a potential genetic basis of EI with regard to attention to one's own feelings involving the serotonin system in males.
authors.affiliation: Department of Psychiatry and Institute of Behavioral Science in Medicine, Yonsei University College of Medicine, Seoul, South Korea.
authors.forename: Se Joo
authors.initials: SJ
authors.lastname: Kim
authors.forename: Jee In
authors.initials: JI
authors.lastname: Kang
authors.forename: Kee
authors.initials: K
authors.lastname: Namkoong
authors.forename: Dong-Ho
authors.initials: DH
authors.lastname: Song
mesh_terms: D000328:Adult; D056348:Emotional Intelligence / Q000235:genetics*; D005260:Female; D005838:Genotype; D006801:Humans; D008297:Male; D008995:Monoamine Oxidase / Q000235:genetics*; D020641:Polymorphism, Single Nucleotide / Q000235:genetics*; D011401:Promoter Regions, Genetic / Q000235:genetics*; D057566:Self Report; D050486:Serotonin Plasma Membrane Transport Proteins / Q000235:genetics*; D012727:Sex Characteristics; D014365:Tryptophan Hydroxylase / Q000235:genetics
chemical_list: C493230:SLC6A4 protein, human; D050486:Serotonin Plasma Membrane Transport Proteins; C497467:TPH1 protein, human; D014365:Tryptophan Hydroxylase; D008995:Monoamine Oxidase