title: Responsive neurostimulation for the treatment of epilepsy.
abstract: Neurostimulation in epilepsy has witnessed a century-long evolution that has resulted in the use of neurostimulation to both modulate and suppress abnormal neuronal firing. The recent development of advanced responsive stimulation via a closed-loop device (the RNS System) has provided evidence that surgical epilepsy treatment continues to move toward the possibility of reducing or eliminating seizures in medically refractory patients.
authors.affiliation: Department of Neurological Surgery, Columbia University, New York, NY 10032, USA. pg2223@columbia.edu
authors.forename: Paul R
authors.initials: PR
authors.lastname: Gigante
authors.forename: Robert R
authors.initials: RR
authors.lastname: Goodman
mesh_terms: D000818:Animals; D046690:Deep Brain Stimulation / Q000266:history*; D004599:Electric Stimulation Therapy / Q000266:history*; D004827:Epilepsy / Q000266:history* / Q000628:therapy; D049672:History, 19th Century; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans