title: Characterization of Acinetobacter baumannii from intensive care units and home care patients in Palermo, Italy.
abstract: In this study 45 isolates of Acinetobacter baumannii identified from patients in intensive care units of three different hospitals and from pressure ulcers in home care patients in Palermo, Italy, during a 3-month period in 2010, were characterized. All isolates were resistant to at least three classes of antibiotics, but susceptible to colistin and tygecycline. Forty isolates were non-susceptible to carbapenems. Eighteen and two isolates, respectively, carried the bla(OXA-23-like) and the bla(OXA-58-like) genes. One strain carried the VIM-4 gene. Six major rep-PCR subtype clusters were defined, including isolates from different hospitals or home care patients. The sequence type/pulsed field gel electrophoresis group ST2/A included 33 isolates, and ST78/B the remaining 12. ST2 clone proved to be predominant, but a frequent involvement of the ST78 clone was evident.
authors.affiliation: Department of Sciences for Health Promotion G. D'Alessandro, Section of Hygiene, University, Palermo, Italy. diptigmi@unipa.it
authors.forename: C
authors.initials: C
authors.lastname: Mammina
authors.forename: C
authors.initials: C
authors.lastname: Bonura
authors.forename: A
authors.initials: A
authors.lastname: Aleo
authors.forename: C
authors.initials: C
authors.lastname: Calà
authors.forename: G
authors.initials: G
authors.lastname: Caputo
authors.forename: M C
authors.initials: MC
authors.lastname: Cataldo
authors.forename: A
authors.initials: A
authors.lastname: Di Benedetto
authors.forename: S
authors.initials: S
authors.lastname: Distefano
authors.forename: T
authors.initials: T
authors.lastname: Fasciana
authors.forename: M
authors.initials: M
authors.lastname: Labisi
authors.forename: C
authors.initials: C
authors.lastname: Sodano
authors.forename: D M
authors.initials: DM
authors.lastname: Palma
authors.forename: A
authors.initials: A
authors.lastname: Giammanco
mesh_terms: D000151:Acinetobacter Infections / Q000382:microbiology*; D040981:Acinetobacter baumannii / Q000187:drug effects / Q000235:genetics / Q000302:isolation & purification*; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D016000:Cluster Analysis; D017714:Community-Acquired Infections / Q000382:microbiology*; D003428:Cross Infection / Q000382:microbiology*; D024901:Drug Resistance, Multiple, Bacterial; D016521:Electrophoresis, Gel, Pulsed-Field; D005838:Genotype; D006699:Home Care Services; D006801:Humans; D007362:Intensive Care Units; D007558:Italy; D008826:Microbial Sensitivity Tests; D058889:Molecular Typing; D058885:Multilocus Sequence Typing; D001618:beta-Lactamases / Q000235:genetics
chemical_list: D000900:Anti-Bacterial Agents; D001618:beta-Lactamases