title: Detection and genetic characterization of a novel pig astrovirus: relationship to other astroviruses.
abstract: Emerging viruses represent a continuous threat to human health and to farmed animals, as evidenced on multiple occasions by outbreaks of influenza, henipavirus and SARS. Knowledge about the diversity of viromes present in reservoir species can lead to a better understanding of the origin of emerging pathogens. In this study, we extend the knowledge of astrovirus diversity in pigs by reporting the genetic characterization of an unknown astrovirus lineage. Phylogenetic analyses provided evidence that this porcine astrovirus lineage is unique and does not appear to share a recent common ancestor with any known mamastrovirus. The data reported in this study extend the number of porcine astrovirus lineages to a total of five, all of which most likely represent distinct species of different origins.
authors.affiliation: Canadian Food Inspection Agency, St-Hyacinthe Laboratory, 3400 Blvd Casavant West, St-Hyacinthe, QC, J2S 8E3, Canada.
authors.forename: Marc-André
authors.initials: MA
authors.lastname: Laurin
authors.forename: Margaux
authors.initials: M
authors.lastname: Dastor
authors.forename: Yvan
authors.initials: Y
authors.lastname: L'homme
mesh_terms: D000818:Animals; D019200:Astroviridae / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification*; D019350:Astroviridae Infections / Q000662:veterinary* / Q000821:virology*; D014644:Genetic Variation; D006801:Humans; D008969:Molecular Sequence Data; D010802:Phylogeny; D034421:Sus scrofa; D013552:Swine; D013553:Swine Diseases / Q000821:virology*