title: Acute change in left ventricle end-diastolic pressure after primary percutaneous coronary intervention in patients with ST segment elevation myocardial infarction.
abstract: ST segment elevation myocardial infarction (STEMI) causes decreasing left ventricle compliance, increasing left ventricle end-diastolic pressure (LVEDP), and diastolic dysfunctioning. It is known that primary percutaneous coronary intervention (PCI) has an acute effect on left ventricle compliance.
  
  
  OBJECTIVE
  This study aims to determine whether left ventricle diastolic function improves and LVEDP decreases post-PCI in patients with STEMI.
  
  
  METHODS
  Twenty-nine patients (21 male, mean age 62 ± 12) diagnosed with a first anterior or inferior STEMI and hospitalized in the first six hours were enrolled. Coronary angiography (CAG) showed occlusion of the right coronary artery (RCA), circumflex (Cx), or left anterior descending (LAD) coronary artery. Aortic pressure and LVEDP were measured and compared before and after PCI.
  
  
  RESULTS
  After successful reperfusion, left ventricle diastolic function improved and LVEDP decreased significantly. Decrease in mean LVEDP was 5.7 ± 2.9 mmHg (p=0.0005) and 4.9 ± 6.5 mmHg (p=0.026) in inferior and anterior MI, respectively. Clinical and electrocardiographic (ECG) findings improved quickly.
  
  
  CONCLUSIONS
  Primary PCA provides rapid improvement of LVEDP and diastolic functions in both anterior and inferior MI. Left ventricular pressure (before and after PCI) can be measured during the procedure without any complication, so it can be used for quick evaluation of left ventricular diastolic function improvement.
authors.affiliation: Cardiology Department, Medical Faculty, Rize University, Turkey. omersatiroglu@yahoo.com
authors.forename: Omer
authors.initials: O
authors.lastname: Satıroğlu
authors.forename: Yüksel
authors.initials: Y
authors.lastname: Ciçek
authors.forename: Mehmet
authors.initials: M
authors.lastname: Bostan
authors.forename: Mustafa
authors.initials: M
authors.lastname: Cetin
authors.forename: Engin
authors.initials: E
authors.lastname: Bozkurt
mesh_terms: D017023:Coronary Angiography; D003971:Diastole; D004562:Electrocardiography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000150:complications / Q000000981:diagnostic imaging / Q000628:therapy*; D015425:Myocardial Reperfusion / Q000379:methods*; D011379:Prognosis; D012307:Risk Factors; D015996:Survival Rate; D016896:Treatment Outcome; D018487:Ventricular Dysfunction, Left / Q000000981:diagnostic imaging / Q000209:etiology / Q000628:therapy*; D017725:Ventricular Pressure