title: [Good response of scleromyxedema and dermato-neuro syndrome to treatment with intravenous immunoglobulins].
abstract: Scleromyxedema is a potentially serious disease that can have various systemic complications. One of the most frequent forms of central nervous system involvement is dermato-neuro syndrome. High-dose intravenous immunoglobulins are among the drug treatments that have been used for this syndrome. We describe 2 patients with scleromyxedema, one of whom developed dermato-neuro syndrome. Both patients responded well to treatment with high-dose intravenous immunoglobulins. We suggest this therapy as a suitable first-line treatment for scleromyxedema and for its neurological complications.
authors.affiliation: Servicio de Dermatología, Hospital Universitari Germans Trias i Pujol, Badalona, Universitat Autònoma de Barcelona, España. ibielsa.germanstrias@gencat.cat
authors.forename: I
authors.initials: I
authors.lastname: Bielsa
authors.forename: F
authors.initials: F
authors.lastname: Benvenutti
authors.forename: R M
authors.initials: RM
authors.lastname: Guinovart
authors.forename: C
authors.initials: C
authors.lastname: Ferrándiz
mesh_terms: D000368:Aged; D005260:Female; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D009422:Nervous System Diseases / Q000188:drug therapy* / Q000209:etiology*; D053718:Scleromyxedema / Q000150:complications* / Q000188:drug therapy*; D013577:Syndrome
chemical_list: D016756:Immunoglobulins, Intravenous