title: Prevalence of unrecognized myocardial infarction detected with magnetic resonance imaging and its relationship to cerebral ischemic lesions in both sexes.
abstract: OBJECTIVE
  The purpose of this study was to investigate the prevalence of unrecognized myocardial infarction (UMI) detected with magnetic resonance imaging (MRI) and whether it is related to cerebral ischemic lesions on MRI in an elderly population-based cohort.
  
  
  BACKGROUND
  There is a correlation between stroke and recognized myocardial infarction (RMI) and between stroke and UMI detected with electrocardiography, whereas the prevalence of stroke in subjects with MRI-detected UMI is unknown.
  
  
  METHODS
  Cerebral MRI and cardiac late-enhancement MRI were performed on 394 randomly selected 75-year-old subjects (188 women, 206 men). Images were assessed for cerebral ischemic lesions and myocardial infarction (MI) scars. Medical records were scrutinized. Subjects with MI scars, with or without a hospital diagnosis of MI, were classified as RMI or UMI, respectively.
  
  
  RESULTS
  UMIs were found in 120 subjects (30%) and RMIs in 21 (5%). The prevalence of UMIs (p = 0.004) and RMIs (p = 0.02) was greater in men than in women. Men with RMI displayed an increased prevalence of cortical and lacunar cerebral infarctions, whereas women with UMI more frequently had cortical cerebral infarctions (p = 0.003).
  
  
  CONCLUSIONS
  MI scars are more frequent in men than in women at 75 years of age. The prevalence of RMI is related to that of cerebral infarctions.
authors.affiliation: Department of Radiology, Uppsala University Hospital, Uppsala, Sweden. Charlotte.Ebeling_Barbier@radiol.uu.se
authors.forename: Charlotte Ebeling
authors.initials: CE
authors.lastname: Barbier
authors.forename: Ruta
authors.initials: R
authors.lastname: Nylander
authors.forename: Raquel
authors.initials: R
authors.lastname: Themudo
authors.forename: Håkan
authors.initials: H
authors.lastname: Ahlström
authors.forename: Lars
authors.initials: L
authors.lastname: Lind
authors.forename: Elna-Marie
authors.initials: EM
authors.lastname: Larsson
authors.forename: Tomas
authors.initials: T
authors.lastname: Bjerner
authors.forename: Lars
authors.initials: L
authors.lastname: Johansson
mesh_terms: D000368:Aged; D002545:Brain Ischemia / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology*; D003937:Diagnosis, Differential; D003951:Diagnostic Errors / Q000706:statistics & numerical data*; D004562:Electrocardiography; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D009203:Myocardial Infarction / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology*; D015995:Prevalence; D012189:Retrospective Studies; D018570:Risk Assessment / Q000379:methods*; D012307:Risk Factors; D017678:Sex Distribution; D012737:Sex Factors; D013548:Sweden / Q000453:epidemiology