title: [Pulmonary non-infectious diseases in common variable immunodeficiency].
abstract: Few studies have described pulmonary non-infectious diseases (PNID) in patients with common variable immunodeficiency (CVID). Indeed the most frequent complications in these patients are infectious. The aim of our study is to analyze the characteristics of PNID in a retrospective study of patients with CVID of two pneumology departments in Paris (France), from 1990 to 2008. PNID was observed in 11 patients. Mean immunoglobulin serum level was 3.46g/L. The PNID observed were: arteriovenous pulmonary fistula: three; interstitial lung disease: three; asthma: two; mediastinal lymphadenopathy: four; emphysema: one; mesothelioma: one. Our study outlines the broad spectrum of pulmonary manifestations related to CVID. Clinicians should be aware of the diagnosis of PNID even in patients without classic infectious manifestations.
authors.affiliation: Service de Pneumologie, Hôpital Foch, 40, rue Worth, 92150 Suresnes, France. camillebron@hotmail.com
authors.forename: C
authors.initials: C
authors.lastname: Bron
authors.forename: E
authors.initials: E
authors.lastname: Catherinot
authors.forename: J
authors.initials: J
authors.lastname: Cadranel
authors.forename: E
authors.initials: E
authors.lastname: Oksenhendler
authors.forename: E
authors.initials: E
authors.lastname: Rivaud
authors.forename: L-J
authors.initials: LJ
authors.lastname: Couderc
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D017074:Common Variable Immunodeficiency / Q000150:complications*; D005260:Female; D006801:Humans; D008171:Lung Diseases / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D055815:Young Adult