title: Preparation of magnetically separable N-halamine nanocomposites for the improved antibacterial application.
abstract: Magnetic N-halamine nanocomposites were synthesized through the encapsulation of the magnetic silica nanoparticles with antibacterial N-halamine polymer. The as-synthesized sample was characterized by transmission electron microscopy (TEM), dynamic light scattering (DLS), Fourier transform infrared (FTIR), X-ray diffraction (XRD), X-ray photoelectron spectra (XPS), and thermogravimetric analysis (TGA). The fabricated magnetic N-halamine nanocomposites possessed enhanced antibacterial activity against both gram-positive and gram-negative bacteria compared with their bulk counterparts. The effect of chlorine content of the magnetic N-halamine nanocomposites on the antibacterial activity was investigated. The magnetic N-halamine nanocomposites also exhibited super-paramagnetic behavior and had a saturation magnetization of 4.728 emu g(-1) at room temperature, which made these nanocomposites separable magnetically after the antibacterial behavior. Performances derived from the synergism between magnetic core and antibacterial shell suggest that the magnetic N-halamine nanocomposites are qualified for antibacterial applications and separable by the aid of the external magnetic field.
authors.affiliation: College of Chemistry, Jilin University and MacDiarmid Laboratory, Changchun 130021, People's Republic of China.
authors.forename: Alideertu
authors.initials: A
authors.lastname: Dong
authors.forename: Shi
authors.initials: S
authors.lastname: Lan
authors.forename: Jinfeng
authors.initials: J
authors.lastname: Huang
authors.forename: Tao
authors.initials: T
authors.lastname: Wang
authors.forename: Tianyi
authors.initials: T
authors.lastname: Zhao
authors.forename: Weiwei
authors.initials: W
authors.lastname: Wang
authors.forename: Linghan
authors.initials: L
authors.lastname: Xiao
authors.forename: Xin
authors.initials: X
authors.lastname: Zheng
authors.forename: Fengqi
authors.initials: F
authors.lastname: Liu
authors.forename: Ge
authors.initials: G
authors.lastname: Gao
authors.forename: Yuxin
authors.initials: Y
authors.lastname: Chen
mesh_terms: D000588:Amines / Q000737:chemistry* / Q000302:isolation & purification; D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000494:pharmacology; D006090:Gram-Negative Bacteria / Q000187:drug effects; D006094:Gram-Positive Bacteria / Q000187:drug effects; D008280:Magnetics; D008826:Microbial Sensitivity Tests; D046529:Microscopy, Electron, Transmission; D053761:Nanocomposites; D017550:Spectroscopy, Fourier Transform Infrared; D014961:X-Ray Diffraction
chemical_list: D000588:Amines; D000900:Anti-Bacterial Agents