title: Recurrent Miller Fisher syndrome with vestibular involvement.
abstract: We describe a patient who had four relapses of Miller Fisher syndrome over a period of 20 years. The classical triad - ophthalmoparesis, ataxia and areflexia - was present during the first two attacks; ataxia was not observed during the third episode. The final recurrence was characterized by signs suggestive of a central involvement of the oculomotor pathways, subclinical slowing of the visual-evoked potentials, and peripheral vestibular hyporeactivity. Brain imaging was normal, but high levels of anti-GQ1b IgG antibodies were detectable during the second relapse and persisted after the fourth recurrence despite complete clinical recovery.
authors.affiliation: Service de Neurologie et Laboratoire de Neurochimie, Université Catholique de Louvain, Brussels, Belgium.
authors.forename: G
authors.initials: G
authors.lastname: Vermeersch
authors.forename: A
authors.initials: A
authors.lastname: Boschi
authors.forename: N
authors.initials: N
authors.lastname: Deggouj
authors.forename: V
authors.initials: V
authors.lastname: van Pesch
authors.forename: C J M
authors.initials: CJ
authors.lastname: Sindic
mesh_terms: D000293:Adolescent; D002150:Caloric Tests; D007839:Functional Laterality; D006801:Humans; D008297:Male; D019846:Miller Fisher Syndrome / Q000150:complications*; D012438:Saccades; D015837:Vestibular Diseases / Q000209:etiology*; D014722:Vestibule, Labyrinth / Q000503:physiopathology