title: Regioselective synthesis of 1,3,5-substituted benzenes via the InCl(3)/2-iodophenol-catalyzed cyclotrimerization of alkynes.
abstract: A novel indium(III)-catalyzed cyclotrimerization of alkynes in the presence of 2-iodophenol gave 1,3,5-substituted benzenes in excellent yields with complete regioselectivity. The reaction condition is tolerant to air, and atom economical, in accordance with the concept of modern green chemistry. This method provides a rapid and efficient access to 1,3,5-substituted benzenes.
authors.affiliation: Key Laboratory for the Chemistry and Molecular Engineering of Medicinal Resources (Ministry of Education of China), School of Chemistry & Chemical Engineering of Guangxi Normal University, Guilin 541004, People's Republic of China.
authors.forename: Yan-li
authors.initials: YL
authors.lastname: Xu
authors.forename: Ying-ming
authors.initials: YM
authors.lastname: Pan
authors.forename: Qiang
authors.initials: Q
authors.lastname: Wu
authors.forename: Heng-shan
authors.initials: HS
authors.lastname: Wang
authors.forename: Pei-zhen
authors.initials: PZ
authors.lastname: Liu
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D001554:Benzene / Q000737:chemistry*; D002384:Catalysis; D002625:Chemistry, Organic / Q000379:methods*; D003500:Cyclization; D055772:Green Chemistry Technology; D007204:Indium / Q000737:chemistry*; D007462:Iodobenzenes / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D058105:Polymerization; D012997:Solvents; D013237:Stereoisomerism
chemical_list: D000480:Alkynes; D007462:Iodobenzenes; D012997:Solvents; D007204:Indium; C020758:indium trichloride; C011289:2-iodophenol; D001554:Benzene