title: [Emotion and Brodmann's areas: special reference on area 12].
abstract: Brodmann's brain maps, assembled in 1909, are still in use, but understanding of their animal-human homology is uncertain. Furthermore, in 1909, Brodmann did not identify human Area 12 (BA12); a location now important to understanding of frontotemporal lobar degeneration (FTLD) and emotional function. We found Brodmann did identify human BA12 in later maps (1910 and 1914), not in the 1909 monograph. Because of its current link with FTLD, BA 12's translation from animal (1909) to human (1910 and 1914) is not only an historical puzzle. It impacts how Brodmann's areas, based on comparative animal-human cyto-architecture, are widely used in current research as functional loci in human brain. If Brodmann's maps are of current value, then an accurate rather than a generic Brodmann number is in order.
authors.affiliation: Department of Neurology, Showa University School of Medicine.
authors.forename: Mitsuru
authors.initials: M
authors.lastname: Kawamura
mesh_terms: D000818:Animals; D001931:Brain Mapping; D004644:Emotions / Q000502:physiology*; D005625:Frontal Lobe / Q000502:physiology*; D057174:Frontotemporal Lobar Degeneration / Q000503:physiopathology / Q000523:psychology; D006801:Humans