title: Fast and protecting-group-free synthesis of (±)-subincanadine C.
abstract: The first total synthesis of (±)-subincanadine C has been accomplished in a protecting-group-free fashion. This pentacyclic indole alkaloid was synthesized in six steps from the known intermediate 4, featuring Ni(COD)(2)-mediated intramolecular Michael addition as a key transformation.
authors.affiliation: Key Laboratory of Synthetic Chemistry of Natural Substances, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China.
authors.forename: Fangmiao
authors.initials: F
authors.lastname: Yu
authors.forename: Bin
authors.initials: B
authors.lastname: Cheng
authors.forename: Hongbin
authors.initials: H
authors.lastname: Zhai
mesh_terms: D004952:Esters / Q000737:chemistry; D026121:Indole Alkaloids / Q000138:chemical synthesis*; D015394:Molecular Structure; D013997:Time Factors
chemical_list: D004952:Esters; D026121:Indole Alkaloids; C472462:subincanadine C