title: Adverse reaction to metal release from a modular metal-on-polyethylene hip prosthesis.
abstract: A 70-year-old man with an uncemented metal-on-polyethylene total hip prosthesis underwent revision arthroplasty 33 months later because of pain, swelling and recurrent dislocation. There appeared to be corrosion and metal release from the prosthetic head, resulting in pseudotumour formation and severe local soft-tissue destruction. The corrosion occurred at the junction between the titanium-molybdenum-zirconium-iron taper and the cobalt-chrome-molybdenum head, but the mechanism was unproven.
authors.affiliation: Karolinska University Hospital, Department of Orthopaedics K54, Huddinge, S14186 Stockholm, Sweden. urban.lindgren@ki.se
authors.forename: J U
authors.initials: JU
authors.lastname: Lindgren
authors.forename: B H
authors.initials: BH
authors.lastname: Brismar
authors.forename: A C
authors.initials: AC
authors.lastname: Wikstrom
mesh_terms: D000368:Aged; D019644:Arthroplasty, Replacement, Hip / Q000379:methods; D003343:Corrosion; D006104:Granuloma, Plasma Cell / Q000000981:diagnostic imaging / Q000209:etiology; D006622:Hip Prosthesis / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008670:Metals / Q000009:adverse effects*; D020959:Polyethylene; D011474:Prosthesis Design; D011475:Prosthesis Failure; D012086:Reoperation / Q000379:methods; D014057:Tomography, X-Ray Computed
chemical_list: D008670:Metals; D020959:Polyethylene