title: Clinical effectiveness of a special silk textile in the treatment of recurrent pediatric inflammatory vulvitis: an open label pilot study.
abstract: OBJECTIVE
  Pediatric inflammatory vulvitis (PIV) is clinically characterized by itching, soreness and inflammation and can be due to both an infective process and a non-specific irritative process, especially in atopic patients. Sometimes these non-specific PIVs, that tend to be recurrent, can be overinfected, with exacerbation of the clinical features. The importance of the cleansers, emollients, and the kind of textiles that enter in direct contact all day long with the inflamed skin, is well known. The study objective is the evaluation of the safety and efficacy of the transpiring, slightly elastic knitted silk briefs, with anti-bacterial and non-irritating properties, registered as Dermasilk®, in recurrent PIV.
  
  
  METHODS
  The study we conducted was a prospective cohort study of 12 pre-pubertal girls, aged between 2 and 10 years, affected by recurrent PIV, that used Dermasilk® briefs in association to conventional treatments.
  
  
  RESULTS
  Dermasilk® briefs have proven to be an effective and safe adjuvant product available for use in association with conventional drugs for the treatment of recurrent PIV.
  
  
  CONCLUSIONS
  Dermasilk® briefs play an important role in the management of the flares of recurrent PIV, proven by an earlier resolution of symptoms, as well as in the maintenance of the remission and in the prevention of overinfections.
authors.affiliation: Department of Internal Medicine, Geriatrics and Nephrology, University of Bologna, Bologna, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Patrizi
authors.forename: F
authors.initials: F
authors.lastname: Giacomini
authors.forename: C
authors.initials: C
authors.lastname: Gurioli
authors.forename: I
authors.initials: I
authors.lastname: Neri
mesh_terms: D002648:Child; D002675:Child, Preschool; D003020:Clothing; D005260:Female; D006801:Humans; D010865:Pilot Projects; D011446:Prospective Studies; D012008:Recurrence; D047011:Silk; D013784:Textiles; D014847:Vulvitis / Q000628:therapy*
chemical_list: D047011:Silk