title: High-resolution optical coherence tomography retinal imaging: a case series illustrating potential and limitations.
abstract: Purpose. To present a series of retinal disease cases that were imaged by spectral domain optical coherence tomography (SD-OCT) in order to illustrate the potential and limitations of this new imaging modality. Methods. The series comprised four selected cases (one case each) of age-related macular degeneration (ARMD), diabetic retinopathy (DR), central retinal artery occlusion (CRAO), and branch retinal vein occlusion (BRVO). Patients were imaged using the Heidelberg Spectralis (Heidelberg Engineering, Germany) in SD-OCT mode. Patients also underwent digital fundus photography and clinical assessment. Results. SD-OCT imaging of a case of age-related macular degeneration revealed a subfoveal choroidal neovascular membrane with detachment of the retinal pigment epithelium (RPE) and neurosensory retina. Using SD-OCT, the cases of DR and BRVO both exhibited macular edema with cystoid spaces visible in the outer retina. Conclusions. The ability of SD-OCT to clearly and objectively elucidate subtle morphological changes within the retinal layers provides information that can be used to formulate diagnoses with greater confidence.
authors.affiliation: Retina Research Group, Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, ON, M5T 2S8, Canada.
authors.forename: Olena
authors.initials: O
authors.lastname: Puzyeyeva
authors.forename: Wai Ching
authors.initials: WC
authors.lastname: Lam
authors.forename: John G
authors.initials: JG
authors.lastname: Flanagan
authors.forename: Michael H
authors.initials: MH
authors.lastname: Brent
authors.forename: Robert G
authors.initials: RG
authors.lastname: Devenyi
authors.forename: Mark S
authors.initials: MS
authors.lastname: Mandelcorn
authors.forename: Tien
authors.initials: T
authors.lastname: Wong
authors.forename: Christopher
authors.initials: C
authors.lastname: Hudson