title: Influence of blue light-filtering intraocular lenses on retinal nerve fiber layer measurements by spectral-domain optical coherence tomography.
abstract: OBJECTIVE
  The purpose of this study was to assess the influence of blue light-filtering intraocular lenses (IOL) on peripapillary retinal nerve fiber layer (RNFL) thickness measurements by spectral-domain (SD) optical coherence tomography (OCT).
  
  
  METHODS
  This prospective study included 50 eyes of 50 patients. Patients were randomly assigned to receive either a blue light-filtering IOL (acrysof IQ (SN60WF) [Alcon]) or a clear IOL (Tecnis (Z9003) [AMO]). The peripapillary RNFL thickness was measured using a Cirrus SD OCT before and 8 weeks after cataract surgery. Perioperative differences in RNFL thickness measurements and signal strengths (SS) were evaluated and compared in both IOL groups.
  
  
  RESULTS
  Thirty-nine eyes of 39 patients were included in the final analysis. There was a significant increase in average RNFL thickness and SS after cataract surgery in both IOL groups. No significant difference in perioperative changes of RNFL measurements was noted between yellow and clear IOL groups. In the multivariable analysis, the factor affecting perioperative differences of RNFL measurements was not IOL type but SS.
  
  
  CONCLUSIONS
  Our data suggests that blue-light filtering IOL does not influence RNFL thickness measurements by Cirrus SD-OCT.
authors.affiliation: Institute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Seodaemun-gu, Seoul, Korea.
authors.forename: Ji Hyun
authors.initials: JH
authors.lastname: Kim
authors.forename: Na Rae
authors.initials: NR
authors.lastname: Kim
authors.forename: Eun Suk
authors.initials: ES
authors.lastname: Lee
authors.forename: Seungsoo
authors.initials: S
authors.lastname: Rho
authors.forename: Sung Yong
authors.initials: SY
authors.lastname: Kang
authors.forename: Chan Yun
authors.initials: CY
authors.lastname: Kim
mesh_terms: D006801:Humans; D019654:Lens Implantation, Intraocular; D007910:Lenses, Intraocular; D009412:Nerve Fibers / Q000473:pathology*; D018918:Phacoemulsification; D011446:Prospective Studies; D011474:Prosthesis Design; D019591:Pseudophakia / Q000503:physiopathology; D012165:Retinal Ganglion Cells / Q000473:pathology*; D041623:Tomography, Optical Coherence; D014792:Visual Acuity