title: Neurogenic detrusor overactivity in patients with spinal cord injury: evaluation and management.
abstract: Lower urinary tract dysfunction can have a significant impact on patients with spinal cord injury. Over the years, many treatment options have become available. This article reviews the assessment and management of neurogenic detrusor overactivity, with a particular focus on articles from the recent literature. Recent guidelines on the subject will be discussed. Management options include antimuscarinics and bladder emptying measures, botulinum toxin A, and neuromodulation in refractory cases and surgery for intractable cases. Recent and relevant publications in these areas will be summarized and discussed.
authors.affiliation: Department of Urology & Medical Research Council (MRC) Centre for Transplantation, King's College London, King's Health Partners, Guy's Hospital, London, UK. arun.sahai@gstt.nhs.uk
authors.forename: Arun
authors.initials: A
authors.lastname: Sahai
authors.forename: Eduardo
authors.initials: E
authors.lastname: Cortes
authors.forename: Jai
authors.initials: J
authors.lastname: Seth
authors.forename: Muhammad Shamim
authors.initials: MS
authors.lastname: Khan
authors.forename: Jalesh
authors.initials: J
authors.lastname: Panicker
authors.forename: Cornelius
authors.initials: C
authors.lastname: Kelleher
authors.forename: Thomas M
authors.initials: TM
authors.lastname: Kessler
authors.forename: Clare J
authors.initials: CJ
authors.lastname: Fowler
authors.forename: Prokar
authors.initials: P
authors.lastname: Dasgupta
mesh_terms: D019468:Disease Management; D014943:Global Health; D006801:Humans; D015994:Incidence; D009465:Neuromuscular Agents / Q000627:therapeutic use*; D018377:Neurotransmitter Agents / Q000627:therapeutic use; D011379:Prognosis; D013119:Spinal Cord Injuries / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology; D001750:Urinary Bladder, Neurogenic / Q000209:etiology / Q000503:physiopathology / Q000628:therapy; D014554:Urination / Q000502:physiology*; D013520:Urologic Surgical Procedures / Q000379:methods*
chemical_list: D009465:Neuromuscular Agents; D018377:Neurotransmitter Agents