title: [The effect of retinoic acid on the meiosis in the chick embryo (Gallus gallus domesticus)].
abstract: In this study it was shown that the injection of retinoic acid (RA) into incubated eggs on day 9 or 14 induced entry the males germ cells into preleptotene stage of prophase I on day 17, which are absent in the control embryos. At the same time the meiosis marker SCP3 was detected in the germ cells. Which was also absent at control embryos. On day 19 in male embryos the number of male germ cells at the stage preleptoteny increased, but there were no germ cells in the following stages of the prophase of meiosis. In 20-day-old chicks meiotic germ cells were absent. Thus, white it is shown that the influence of RA on the developing chicken embryos induces the entry of germ cells into preleptotene stage of prophase I meiosis. However, further meiotic transformations don't occur. Thus RA is only one of many factors providing meiotic cell division.
authors.forename: A A
authors.initials: AA
authors.lastname: Nekrasova
authors.forename: N A
authors.initials: NA
authors.lastname: Lukina
authors.forename: L V
authors.initials: LV
authors.lastname: Kozikova
authors.forename: A F
authors.initials: AF
authors.lastname: Smirnov
mesh_terms: D000818:Animals; D002642:Chick Embryo; D005455:Fluorescent Antibody Technique; D005854:Germ Cells / Q000166:cytology / Q000187:drug effects*; D006066:Gonads / Q000166:cytology / Q000187:drug effects* / Q000196:embryology / Q000378:metabolism; D008297:Male; D008540:Meiosis / Q000187:drug effects*; D009924:Organ Culture Techniques; D012733:Sex Differentiation / Q000502:physiology*; D013573:Synaptonemal Complex / Q000378:metabolism; D014212:Tretinoin / Q000494:pharmacology*
chemical_list: D014212:Tretinoin