title: Trabecular microstructure of the human lunate in Kienbock's disease.
abstract: The trabecular microstructure of normal lunates and lunates with Kienböck's disease was investigated using micro-computed tomography (micro-CT). Five lunates with advanced Kienböck's disease were obtained during lunate excision and scaphocapitate fusion, and five control lunates were from embalmed cadavers. Microstructural morphometric parameters were measured using micro-CT images. Trabeculations of lunates with Kienböck's disease were 2.67 times denser and 1.84 times thicker than those of normal lunates. Furthermore, bone surface areas were 1.43 times greater and bone volume 2.67 times greater, and structural model indices were significantly lower in lunates with Kienböck's disease. The study estimated that high mechanical stress would be applied to lunates with Kienböck's disease, and suggests that new bone formation and collapse may play important roles in the microstructural changes in the lunate with advanced Kienböck's disease.
authors.affiliation: Department of Orthopaedic Surgery, Ajou University School of Medicine, Suwon, Korea.
authors.forename: K-J
authors.initials: KJ
authors.lastname: Han
authors.forename: J Y
authors.initials: JY
authors.lastname: Kim
authors.forename: N-S
authors.initials: NS
authors.lastname: Chung
authors.forename: H R
authors.initials: HR
authors.lastname: Lee
authors.forename: Y S
authors.initials: YS
authors.lastname: Lee
mesh_terms: D000328:Adult; D002348:Carpal Bones / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D021621:Imaging, Three-Dimensional; D012667:Lunate Bone / Q000000981:diagnostic imaging*; D008297:Male; D008852:Microradiography; D008875:Middle Aged; D010020:Osteonecrosis / Q000000981:diagnostic imaging*; D014057:Tomography, X-Ray Computed