title: Brønsted acid-catalyzed enantioselective Friedländer condensations: achiral amine promoter plays crucial role in the stereocontrol.
abstract: A highly enantioselective Friedländer condensation has been established by using chiral Brønsted acids in combination with achiral amines to give quinolines in high yields (up to 99%) and with excellent enantioselectivities (up to 95%).
authors.affiliation: Hefei National Laboratory for Physical Sciences at the Microscale and Department of Chemistry, University of Science and Technology of China, Hefei 230026, People's Republic of China.
authors.forename: Lei
authors.initials: L
authors.lastname: Ren
authors.forename: Tao
authors.initials: T
authors.lastname: Lei
authors.forename: Liu-Zhu
authors.initials: LZ
authors.lastname: Gong
mesh_terms: D000143:Acids / Q000737:chemistry*; D000588:Amines / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000143:Acids; D000588:Amines