title: Antihypertensive Treatment in the Elderly and Very Elderly: Always "the Lower, the Better?".
abstract: Arterial hypertension (HT) is age dependent and, with the prolongation of life expectancy, affects more and more elderly people. In the elderly, HT is a risk factor for organ damage and cardiovascular (CV) events. Both pharmacologic and nonpharmacologic reduction of blood pressure (BP) is associated with a corresponding decrease in systolic-diastolic or isolated systolic HT. Clinical trials have shown that BP lowering is associated with a decrease in stroke and other CV events. Therefore, BP reduction per se appears more important than a particular class of antihypertensive drugs. The benefit of antihypertensive treatment has been confirmed up to the age of 80 years, remaining unclear in the octogenarians. The benefit in lowering diastolic BP between 80 and 90 mmHg is well established, while that of lowering systolic BP below 140 mmHg requires further confirmations.
authors.affiliation: Department of Internal Medicine, "Santa Maria della Misericordia" Hospital, 45100 Rovigo, Italy.
authors.forename: Alberto
authors.initials: A
authors.lastname: Mazza
authors.forename: Emilio
authors.initials: E
authors.lastname: Ramazzina
authors.forename: Stefano
authors.initials: S
authors.lastname: Cuppini
authors.forename: Michela
authors.initials: M
authors.lastname: Armigliato
authors.forename: Laura
authors.initials: L
authors.lastname: Schiavon
authors.forename: Ciro
authors.initials: C
authors.lastname: Rossetti
authors.forename: Marco
authors.initials: M
authors.lastname: Marzolo
authors.forename: Giancarlo
authors.initials: G
authors.lastname: Santoro
authors.forename: Roberta
authors.initials: R
authors.lastname: Ravenni
authors.forename: Marco
authors.initials: M
authors.lastname: Zuin
authors.forename: Sara
authors.initials: S
authors.lastname: Zorzan
authors.forename: Domenico
authors.initials: D
authors.lastname: Rubello
authors.forename: Edoardo
authors.initials: E
authors.lastname: Casiglia