title: Pattern of gynaecological cancers in University of Nigeria Teaching Hospital, Enugu, south eastern Nigeria.
abstract: BACKGROUND
  Gynaecological cancers are among the leading causes of cancer related deaths worldwide. The objective of this study was to determine the pattern and relative frequencies of gynecological cancers as seen at the University of Nigeria Teaching Hospital (UNTH), Ituku/Ozalla, Enugu, Southeastern Nigeria.
  
  
  METHODS
  An analysis of retrospective clinical data from the ward admissions and discharge books and the operating theatre record books.
  
  
  RESULTS
  During the 10-year period under study (2000-2009), 407 cases of gynaecological cancers were admitted into the hospital. The age range of these women was 21-80years with mean age of 54.6 +/- 14.2 years. The commonest gynaecological cancers in women less than 30 years of age were choriocarcinoma (36.1%) and ovarian cancer (33.3%). After 30 years, cervical cancer became the commonest cancer. Overall, cervical cancer was by far the commonest gynecological cancer constituting 78% of all the cases, followed by ovarian cancer (8.9%), choriocarcinoma (4.3%), endometrial cancer (4.1%), vulva cancer (4.0%) and leiomyosarcoma (0.5%). There was no case of vaginal cancer during the study period. Anaemia was the commonest sequelae, complicating 55% of the cases, followed by genital fistulae (12%), infertility (3%), renal failure (3%), and pulmonary complications (2%).
  
  
  CONCLUSIONS
  Cervical cancer is by far the commonest gynaecological cancer in Enugu and there is high incidence of this cancer even in young women below the age of 30 years. The commonest gynaecological cancer in women less than 30 years is choriocarcinoma, and anaemia is the commonest sequelae of all gynaecological cancers.
authors.affiliation: Department of Obstetrics/Gynaecology, University of Nigeria Teaching Hospital, Ituku-Ozalla, Enugu.
authors.forename: E O
authors.initials: EO
authors.lastname: Ugwu
authors.forename: E S
authors.initials: ES
authors.lastname: Iferikigwe
authors.forename: T C
authors.initials: TC
authors.lastname: Okeke
authors.forename: A O
authors.initials: AO
authors.lastname: Ugwu
authors.forename: O A
authors.initials: OA
authors.lastname: Okezie
authors.forename: P U
authors.initials: PU
authors.lastname: Agu
mesh_terms: D000328:Adult; D017677:Age Distribution; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005833:Genital Neoplasms, Female / Q000453:epidemiology* / Q000473:pathology; D006784:Hospitals, Teaching / Q000706:statistics & numerical data; D006801:Humans; D008875:Middle Aged; D009549:Nigeria / Q000453:epidemiology; D011247:Pregnancy; D012189:Retrospective Studies; D012959:Socioeconomic Factors; D055815:Young Adult