title: Posterior reversible encephalopathy syndrome associated with deoxycoformycin and alemtuzumab.
abstract: Posterior reversible encephalopathy syndrome (PRES) is a combined clinical and radiological syndrome characterised by headaches, encephalopathy, seizures and visual loss. We present the case of a 55-year-old male who developed this condition following treatment with deoxycoformycin and alemtuzumab. We review the literature considering diagnosis, pathophysiology and optimal strategies for treatment of this condition.
authors.affiliation: Department of Critical Care, The Christie, Manchester, UK. cooks199@hotmail.com
authors.forename: T
authors.initials: T
authors.lastname: Cooksley
authors.forename: P
authors.initials: P
authors.lastname: Haji-Michael
mesh_terms: D000074323:Alemtuzumab; D061067:Antibodies, Monoclonal, Humanized / Q000009:adverse effects*; D000912:Antibodies, Neoplasm / Q000009:adverse effects*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects*; D006801:Humans; D008297:Male; D015649:Pentostatin / Q000009:adverse effects*; D054038:Posterior Leukoencephalopathy Syndrome / Q000139:chemically induced*
chemical_list: D061067:Antibodies, Monoclonal, Humanized; D000912:Antibodies, Neoplasm; D015649:Pentostatin; D000074323:Alemtuzumab