title: An Interview with Matthew P. Greving, PhD. Interview by Vicki Glaser.
abstract: Matthew P. Greving is Chief Scientific Officer at Nextval Inc., a company founded in early 2010 that has developed a discovery platform called MassInsight™.. He received his PhD in Biochemistry from Arizona State University, and prior to that he spent nearly 7 years working as a software engineer. This experience in solving complex computational problems fueled his interest in developing technologies and algorithms related to acquisition and analysis of high-dimensional biochemical data. To address the existing problems associated with label-based microarray readouts, he beganwork on a technique for label-free mass spectrometry (MS) microarray readout compatible with both matrix-assisted laser/desorption ionization (MALDI) and matrix-free nanostructure initiator mass spectrometry (NIMS). This is the core of Nextval’s MassInsight technology, which utilizes picoliter noncontact deposition of high-density arrays on mass-readout substrates along with computational algorithms for high-dimensional data processingand reduction.
authors.forename: Matthew P
authors.initials: MP
authors.lastname: Greving
mesh_terms: D000465:Algorithms; D003198:Computer Simulation; D055808:Drug Discovery / Q000379:methods*; D004345:Drug Industry / Q000379:methods; D057166:High-Throughput Screening Assays / Q000379:methods; D006801:Humans; D036103:Nanotechnology; D040901:Proteomics / Q000379:methods*; D012984:Software; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / Q000379:methods