title: The possible introduction of anti-osteoporosis drugs as an integrated treatment in total hip arthroplasty.
abstract: The anchorage of cementless total hip arthroplasty relies on a direct bone to implant bonding. Several factors including material properties and surface treatment determine the interfacial response of the host bone to a foreign material. Another factor that must be taken into account is the bone remodeling after the prosthesis introduction. Considering this bone remodeling, in the last few years the possibility of using anti-osteoporotic drugs has been introduced as a supplementary and integrated treatment in total hip replacement.
authors.affiliation: Clinica Ortopedica dell'Università degli Studi di Brescia, Spedali Civili di Brescia, Spedali Civili di Brescia, Italy. marcellamarchese@libero.it
authors.forename: Marcella
authors.initials: M
authors.lastname: Marchese
authors.forename: Guido
authors.initials: G
authors.lastname: Zarattini
authors.forename: Ugo E
authors.initials: UE
authors.lastname: Pazzaglia
mesh_terms: D019644:Arthroplasty, Replacement, Hip / Q000379:methods*; D050071:Bone Density Conservation Agents / Q000494:pharmacology; D001862:Bone Resorption; D001842:Bone and Bones / Q000473:pathology; D002116:Calcitonin / Q000737:chemistry; D006622:Hip Prosthesis; D006801:Humans; D008422:Materials Testing; D009942:Organometallic Compounds / Q000494:pharmacology; D011474:Prosthesis Design; D053245:RANK Ligand / Q000037:antagonists & inhibitors; D013876:Thiophenes / Q000494:pharmacology
chemical_list: D050071:Bone Density Conservation Agents; D009942:Organometallic Compounds; D053245:RANK Ligand; D013876:Thiophenes; C081587:strontium ranelate; D002116:Calcitonin