title: [Synergic effect of alprostadil injection and ginaton in treating sudden deafness].
abstract: OBJECTIVE
  To explore synergic effect of Alprostadil injection and ginaton in treating sudden deafness.
  
  
  METHODS
  ninety one patients with sudden deafness were divided into group A, group B and group C at random; 33 ears of group A were treated with 70 mg ginaton by vein, 30 ears of group B were treated with 10 microg Alprostadil injection by vein, 31 ears of group C were treated with 10 microg Alprostadil injection and ginaton by vein,once a day, the time of treatment is 14 days.
  
  
  RESULTS
  the effective rate of group A is 60.61%, the effective rate of group B is 60.00%, the effective rate of group C is 87.09% the treating effect was significantly different in the group A and C (P < 0.05), it was significantly different in the group B and C (P < 0.05)).
  
  
  CONCLUSIONS
  It is effective for Alprostadil injection and ginaton to treat sudden deafness, and it has significantly Synergic effect in treating sudden deafness with Alprostadil injection and ginaton.
authors.affiliation: Department of Otorhinolaryngology-Head and Neck Surgery, 305 Hospital, Beijing, 100017, China. 305jiangjiping@163.com
authors.forename: Jiping
authors.initials: J
authors.lastname: Jiang
authors.forename: Shuyun
authors.initials: S
authors.lastname: Wang
authors.forename: Kang
authors.initials: K
authors.lastname: Tong
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000527:Alprostadil / Q000008:administration & dosage / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D003639:Hearing Loss, Sudden / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D055815:Young Adult
chemical_list: D004365:Drugs, Chinese Herbal; C526713:ginaton; D000527:Alprostadil