title: Effects of feeding potato pulp on cholesterol metabolism and its association with cecal conditions in rats.
abstract: To clarify the functional properties of potato pulp (PP), a waste product resulting from extraction of starch from potatoes, we examined the effects of PP on cholesterol metabolism and cecal conditions in rats. Plasma total cholesterol (T-Chol) levels were lower in rats fed a PP-supplemented diet for four weeks than in those fed a control diet. Cecal pH was lowered due to an increase in the levels of cecal total short-chain fatty acids, especially butyrate, in the PP group compared to the control group. Furthermore, animals fed with the PP-supplemented diet showed increased cecal ratios of Lactobacillus and Clostridia and decreased cecal ratios of Bacteroides and Gammaproteobacteria with slightly negative and positive correlations with plasma T-Chol levels, respectively. In conclusion, ingestion of PP for four weeks is likely to improve both cecal conditions and cholesterol metabolism, suggesting that PP has prebiotic effects.
authors.affiliation: Koshi Headquarters, National Agricultural Research Center for Kyushu Okinawa Region, Suya 2421, Koshi, Kumamoto, Japan. hasshy@affrc.go.jp
authors.forename: Naoto
authors.initials: N
authors.lastname: Hashimoto
authors.forename: Yumi
authors.initials: Y
authors.lastname: Nakamura
authors.forename: Takahiro
authors.initials: T
authors.lastname: Noda
authors.forename: Kyu-Ho
authors.initials: KH
authors.lastname: Han
authors.forename: Michihiro
authors.initials: M
authors.lastname: Fukushima
mesh_terms: D000818:Animals; D001439:Bacteroides / Q000254:growth & development; D001835:Body Weight; D002432:Cecum / Q000737:chemistry / Q000382:microbiology*; D002784:Cholesterol / Q000097:blood / Q000378:metabolism*; D003013:Clostridium / Q000254:growth & development*; D004269:DNA, Bacterial / Q000235:genetics; D005232:Fatty Acids, Volatile / Q000378:metabolism*; D005243:Feces / Q000737:chemistry / Q000382:microbiology; D020563:Gammaproteobacteria / Q000254:growth & development; D006863:Hydrogen-Ion Concentration; D007778:Lactobacillus / Q000254:growth & development*; D008297:Male; D009929:Organ Size; D056692:Prebiotics; D051381:Rats; D017208:Rats, Wistar; D012037:Refuse Disposal; D011198:Solanum tuberosum / Q000737:chemistry*; D013997:Time Factors
chemical_list: D004269:DNA, Bacterial; D005232:Fatty Acids, Volatile; D056692:Prebiotics; D002784:Cholesterol