title: A systematic review of microsurgical reconstruction of the jaws using vascularized fibula flap technique in patients with bisphosphonate-related osteonecrosis.
abstract: OBJECTIVE
  The aim of this systematic review was to assess the role of microsurgical reconstruction of the jaws in patients with bisphosphonate-related osteonecrosis, and biological complications after an observation period of at least 12 months.
  
  
  METHODS
  An electronic MEDLINE search supplemented by manual searching was conducted to identify studies reporting data of at least 12 months observation on the microsurgical reconstruction of the jaws in patients with bisphosphonate-related osteonecrosis.
  
  
  RESULTS
  Four studies resulted eligible for the analysis yielded. Three out of five studies were free of complications, with a success rate of 100% as no recurrence of osteonecrosis was registered.
  
  
  CONCLUSIONS
  Microsurgical reconstruction of the jaws represents a valid treatment modality in patients with bisphosphonate-related osteonecrosis at 3rd stage of the disease.
authors.affiliation: Department of Odontostomathology, Faculty of Medicine, University of Sassari. saccoroberto@yahoo.it
authors.forename: Roberto
authors.initials: R
authors.lastname: Sacco
authors.forename: Gianluca
authors.initials: G
authors.lastname: Sacco
authors.forename: Alessandro
authors.initials: A
authors.lastname: Acocella
authors.forename: Silvana
authors.initials: S
authors.lastname: Sale
authors.forename: Nicola
authors.initials: N
authors.lastname: Sacco
authors.forename: Edoardo
authors.initials: E
authors.lastname: Baldoni
mesh_terms: D059266:Bisphosphonate-Associated Osteonecrosis of the Jaw / Q000601:surgery*; D005360:Fibula / Q000601:surgery / Q000637:transplantation*; D006801:Humans; D008866:Microsurgery / Q000379:methods*; D019651:Plastic Surgery Procedures / Q000379:methods*; D013524:Surgical Flaps