title: Exhaustive fluorine scanning toward potent p53-Mdm2 antagonists.
authors.affiliation: Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, PA 15261, USA.
authors.forename: Yijun
authors.initials: Y
authors.lastname: Huang
authors.forename: Siglinde
authors.initials: S
authors.lastname: Wolf
authors.forename: David
authors.initials: D
authors.lastname: Koes
authors.forename: Grzegorz M
authors.initials: GM
authors.lastname: Popowicz
authors.forename: Carlos J
authors.initials: CJ
authors.lastname: Camacho
authors.forename: Tad A
authors.initials: TA
authors.lastname: Holak
authors.forename: Alexander
authors.initials: A
authors.lastname: Dömling
mesh_terms: D001555:Benzene Derivatives / Q000737:chemistry / Q000494:pharmacology; D055808:Drug Discovery; D005461:Fluorine / Q000737:chemistry* / Q000494:pharmacology*; D006801:Humans; D008958:Models, Molecular; D011485:Protein Binding / Q000187:drug effects; D051736:Proto-Oncogene Proteins c-mdm2 / Q000037:antagonists & inhibitors* / Q000378:metabolism; D016159:Tumor Suppressor Protein p53 / Q000037:antagonists & inhibitors* / Q000378:metabolism
chemical_list: D001555:Benzene Derivatives; D016159:Tumor Suppressor Protein p53; D005461:Fluorine; C497206:MDM2 protein, human; D051736:Proto-Oncogene Proteins c-mdm2