title: Synthesis of chiral sulfoximines derived from 3-aminoquinazolinones and their catalysis of enantioselective diethylzinc addition to aldehydes.
abstract: A series of sulfoxides were sulfoximinated using oxidative addition of 3-aminoquinazolinones by lead tetraacetate in the presence of hexamethyldisilazane. They were applied for the first time in catalytic enantioselective addition to aromatic aldehydes with a product enantiopurity (ee) of 92% in the case of 2-methoxybenzaldehyde.
authors.affiliation: Department of Chemistry, Faculty of Science and Letters, Kahramanmaras Sutcu Imam University, 46100, Kahramanmaras, Turkey.
authors.forename: Semistan
authors.initials: S
authors.lastname: Karabuga
authors.forename: Murat
authors.initials: M
authors.lastname: Cakici
authors.forename: Cavit
authors.initials: C
authors.lastname: Kazaz
authors.forename: Ertan
authors.initials: E
authors.lastname: Sahin
authors.forename: Hamdullah
authors.initials: H
authors.lastname: Kilic
authors.forename: Sabri
authors.initials: S
authors.lastname: Ulukanli