title: Mania following addition of hydroxytryptophan to monoamine oxidase inhibitor.
abstract: This case report highlights the risk of nutritional supplements and misinformation obtained from the internet particularly for those on monamine oxdiase inhibitors (MAOIs). Despite sophisticated medical knowledge, this patient, who was taking an MOAI and complying with a tyramine-free diet, used a supplement of hydroxytryptophan that along with the MAOI appears to have precipitated mania, despite no personal or familial history of bipolar disorder.
authors.affiliation: Department of Psychiatry, University of Minnesota, Minneapolis, MN, USA. jose.pardo@va.gov
authors.forename: José V
authors.initials: JV
authors.lastname: Pardo
mesh_terms: D006916:5-Hydroxytryptophan / Q000009:adverse effects* / Q000627:therapeutic use*; D001714:Bipolar Disorder; D004359:Drug Therapy, Combination / Q000009:adverse effects; D006801:Humans; D020407:Internet; D008297:Male; D008875:Middle Aged; D008996:Monoamine Oxidase Inhibitors / Q000627:therapeutic use*; D020230:Serotonin Syndrome / Q000139:chemically induced
chemical_list: D008996:Monoamine Oxidase Inhibitors; D006916:5-Hydroxytryptophan