title: Optical technologies and molecular imaging for cervical neoplasia: a program project update.
abstract: There is an urgent global need for effective and affordable approaches to cervical cancer screening and diagnosis. In developing nations, cervical malignancies remain the leading cause of cancer-related deaths in women. This reality may be difficult to accept given that these deaths are largely preventable; where cervical screening programs have been implemented, cervical cancer-related deaths have decreased dramatically. In developed countries, the challenges of cervical disease stem from high costs and overtreatment. The National Cancer Institute-funded Program Project is evaluating the applicability of optical technologies in cervical cancer. The mandate of the project is to create tools for disease detection and diagnosis that are inexpensive, require minimal expertise, are more accurate than existing modalities, and can be feasibly implemented in a variety of clinical settings. This article presents the status and long-term goals of the project.
authors.affiliation: Imaging Unit, Department of Integrative Oncology, British Columbia Cancer Research Centre, Vancouver, British Columbia, Canada. tbuys@bccrc.ca
authors.forename: Timon P H
authors.initials: TP
authors.lastname: Buys
authors.forename: Scott B
authors.initials: SB
authors.lastname: Cantor
authors.forename: Martial
authors.initials: M
authors.lastname: Guillaud
authors.forename: Karen
authors.initials: K
authors.lastname: Adler-Storthz
authors.forename: Dennis D
authors.initials: DD
authors.lastname: Cox
authors.forename: Clement
authors.initials: C
authors.lastname: Okolo
authors.forename: Oyedunni
authors.initials: O
authors.lastname: Arulogon
authors.forename: Oladimeji
authors.initials: O
authors.lastname: Oladepo
authors.forename: Karen
authors.initials: K
authors.lastname: Basen-Engquist
authors.forename: Eileen
authors.initials: E
authors.lastname: Shinn
authors.forename: José-Miguel
authors.initials: JM
authors.lastname: Yamal
authors.forename: J Robert
authors.initials: JR
authors.lastname: Beck
authors.forename: Michael E
authors.initials: ME
authors.lastname: Scheurer
authors.forename: Dirk
authors.initials: D
authors.lastname: van Niekerk
authors.forename: Anais
authors.initials: A
authors.lastname: Malpica
authors.forename: Jasenka
authors.initials: J
authors.lastname: Matisic
authors.forename: Gregg
authors.initials: G
authors.lastname: Staerkel
authors.forename: Edward Neely
authors.initials: EN
authors.lastname: Atkinson
authors.forename: Luc
authors.initials: L
authors.lastname: Bidaut
authors.forename: Pierre
authors.initials: P
authors.lastname: Lane
authors.forename: J Lou
authors.initials: JL
authors.lastname: Benedet
authors.forename: Dianne
authors.initials: D
authors.lastname: Miller
authors.forename: Tom
authors.initials: T
authors.lastname: Ehlen
authors.forename: Roderick
authors.initials: R
authors.lastname: Price
authors.forename: Isaac F
authors.initials: IF
authors.lastname: Adewole
authors.forename: Calum
authors.initials: C
authors.lastname: MacAulay
authors.forename: Michele
authors.initials: M
authors.lastname: Follen
mesh_terms: D003127:Colposcopy / Q000295:instrumentation / Q000379:methods; D004867:Equipment Design; D005260:Female; D006801:Humans; D008403:Mass Screening; D008857:Microscopy, Interference; D013050:Spectrometry, Fluorescence / Q000379:methods; D013057:Spectrum Analysis; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis* / Q000517:prevention & control