title: [Effect of natural and postradiation volatile secretions of mice on the immune reactivity and blood cellularity of irradiated animals].
abstract: It has been shown that natural and postradiation volatile urinary secretions of mice can remotely restore the immune reactivity and blood indices reduced as a result of exposure of laboratory mice to ionizing radiation. Antibody formation in spleen of gamma-irradiated (1 Gy) CBA strain mice was increased after exposure of both syngeneic and allogeneic animals with urine volatile secretions. Volatile natural secretions of intact mice have a more pronounced antibody stimulating activity than volatile secretions from animals exposed to gamma-radiation. Immunoreactivity ofy-irradiated C57B16 strain mice with low olfactory reactivity increases only after their exposure with volatile secretions of intact syngeneic animals. The total number of leukocytes and lymphocytes in the peripheral blood of gamma-irradiated (1 Gy) inbred mice increases after exposure with secretions obtained from them before irradiation. The role of hemo-signalling in the selective stimulation of immunity and blood content in conditions of radiation damage is discussed.
authors.forename: V G
authors.initials: VG
authors.lastname: Isaeva
authors.forename: B P
authors.initials: BP
authors.lastname: Surinov
mesh_terms: D000818:Animals; D005720:Gamma Rays / Q000009:adverse effects; D007962:Leukocytes / Q000276:immunology*; D008214:Lymphocytes / Q000276:immunology; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D012724:Sex Attractants / Q000276:immunology* / Q000378:metabolism / Q000652:urine*; D013154:Spleen / Q000502:physiology; D014835:Volatilization; D014916:Whole-Body Irradiation
chemical_list: D012724:Sex Attractants