title: Palladium-catalyzed desulfitative C-arylation of a benzo[d]oxazole C-H bond with arene sulfonyl chlorides.
abstract: A palladium-catalyzed direct desulfitative C-arylation of a benzo[d]oxazole C-H bond with arene sulfonyl chlorides is described. The procedure tolerates halo, cyano, nitro, trifluoromethyl, acetyl and acetylamino groups on the phenyl ring of sulfonyl chlorides, providing the arylation products in moderate to good yields. It represents a practical and attractive alternative for the synthesis of 2-aryl benzoxazoles.
authors.affiliation: College of Chemistry & Materials Engineering, Wenzhou University, Wenzhou 325000, People's Republic of China.
authors.forename: Manli
authors.initials: M
authors.lastname: Zhang
authors.forename: Shouhui
authors.initials: S
authors.lastname: Zhang
authors.forename: Miaochang
authors.initials: M
authors.lastname: Liu
authors.forename: Jiang
authors.initials: J
authors.lastname: Cheng
mesh_terms: D001583:Benzoxazoles / Q000737:chemistry*; D002384:Catalysis; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*; D013441:Sulfinic Acids / Q000737:chemistry*
chemical_list: D001583:Benzoxazoles; D013441:Sulfinic Acids; D010165:Palladium; C044255:sulfonyl chloride