title: [Immunomodulating effects of macrolides: areas of possible clinical use in pulmonology].
abstract: The review is devoted to non-antibacterial effects of macrolides in patients with respiratory diseases: bronchial asthma, bronchoectasis, chronic obstructive pulmonary disease, chronic rhinosinusitis, mucoviscidosis, diffuse bronchiolithiasis, severe flu, posttransplantation obliterating bronchiositis. The discussion covers mechanisms of an immunomodulating action of macrolides. Current data base on non-antibacterial effects of macrolides is analysed.
authors.forename: A I
authors.initials: AI
authors.lastname: Sinopal'nikov
mesh_terms: D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D004305:Dose-Response Relationship, Drug; D024881:Drug Resistance, Bacterial; D006801:Humans; D007155:Immunologic Factors / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D018942:Macrolides / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D012140:Respiratory Tract Diseases / Q000188:drug therapy* / Q000276:immunology / Q000382:microbiology; D013997:Time Factors
chemical_list: D000900:Anti-Bacterial Agents; D007155:Immunologic Factors; D018942:Macrolides