title: Cryosurgical treatment of warts: dimethyl ether and propane versus liquid nitrogen - case report and review of the literature.
abstract: For years, dermatologists have relied on cryotherapy with liquid nitrogen as a safe and effective treatment for warts. More recently, several over-the-counter (OTC) wart-freezing therapies have become available. Manufacturers have substituted liquid nitrogen with dimethyl ether and propane (DMEP), and marketed these new preparations to be safe and effective alternatives to in-office cryotherapy with liquid nitrogen. However, data from in vitro studies and comparative studies in humans refute manufacturers' claims that these products reproduce in-office cryotherapy.
authors.affiliation: Children's Mercy Hospital, Kansas City, MO, USA.
authors.forename: Nicholas V
authors.initials: NV
authors.lastname: Nguyen
authors.forename: Craig G
authors.initials: CG
authors.lastname: Burkhart
mesh_terms: D000328:Adult; D003452:Cryosurgery / Q000009:adverse effects / Q000379:methods*; D006801:Humans; D008297:Male; D008738:Methyl Ethers / Q000009:adverse effects / Q000627:therapeutic use*; D009584:Nitrogen / Q000009:adverse effects / Q000627:therapeutic use*; D004366:Nonprescription Drugs / Q000009:adverse effects / Q000627:therapeutic use; D011407:Propane / Q000009:adverse effects / Q000737:chemistry; D016896:Treatment Outcome; D014860:Warts / Q000601:surgery*
chemical_list: D008738:Methyl Ethers; D004366:Nonprescription Drugs; C033413:dimethyl ether; D009584:Nitrogen; D011407:Propane