title: High temperature normal phase liquid chromatography of aromatic hydrocarbons on bare zirconia.
abstract: The normal phase HPLC behavior of a bare zirconia column was studied at temperatures up to 200 °C using a hexane mobile phase. The use of elevated column temperatures significantly decreased the retention of twenty five aromatic model compounds according to the van't Hoff equation (>30-fold decrease for some compounds). Large improvements in peak shape, efficiency (>2.2-fold), aromatic group-type selectivity, and column re-equilibration times (>5-fold) were obtained at elevated temperatures. The thermal decomposition of two polar nitrogen compounds (indole and carbazole) was observed in a hexane/dichloromethane mobile phase at temperatures greater than 100 °C. The first order decomposition of carbazole was studied in further detail.
authors.affiliation: Department of Chemistry, Gunning/Lemieux Chemistry Centre, University of Alberta, Edmonton, AB, Canada T6G 2G2.
authors.forename: Richard E
authors.initials: RE
authors.lastname: Paproski
authors.forename: Chen
authors.initials: C
authors.lastname: Liang
authors.forename: Charles A
authors.initials: CA
authors.lastname: Lucy
mesh_terms: D002227:Carbazoles / Q000737:chemistry; D002853:Chromatography, Liquid / Q000295:instrumentation / Q000379:methods*; D006586:Hexanes / Q000737:chemistry; D006358:Hot Temperature; D006841:Hydrocarbons, Aromatic / Q000737:chemistry*; D007211:Indoles / Q000737:chemistry; D008752:Methylene Chloride / Q000737:chemistry; D008956:Models, Chemical; D015040:Zirconium / Q000737:chemistry*
chemical_list: D002227:Carbazoles; D006586:Hexanes; D006841:Hydrocarbons, Aromatic; D007211:Indoles; C041514:carbazole; D008752:Methylene Chloride; C030374:indole; D015040:Zirconium; C028541:zirconium oxide