title: Sociality, pathogen avoidance, and the neuropeptides oxytocin and arginine vasopressin.
abstract: Both humans and nonhumans have evolved a variety of mechanisms to recognize pathogen threat and a variety of adaptive behavioral responses to minimize exposure to it. Because social interactions facilitate the spread of infection among individuals, the ability to recognize and avoid infected and potentially infected individuals is crucial. The neuropeptides oxytocin (OT) and arginine vasopressin (AVP) are involved in mediating various facets of social behavior, including social recognition and responses to salient social threats. Results of studies with rodents have revealed that OT and AVP are also associated with the olfactory-mediated recognition and avoidance of actually or potentially infected individuals. The evidence reviewed here suggests that OT and AVP likely play parallel roles in modulating the recognition and avoidance of socially relevant pathogen threat in both humans and rodents.
authors.affiliation: Department of Psychology, Social Science Centre, University of Western Ontario, London, Ontario, Canada N6A 5C1. kavalier@uwo.ca
authors.forename: Martin
authors.initials: M
authors.lastname: Kavaliers
authors.forename: Elena
authors.initials: E
authors.lastname: Choleris
mesh_terms: D000818:Animals; D001127:Arginine Vasopressin / Q000502:physiology*; D001362:Avoidance Learning / Q000502:physiology*; D001522:Behavior, Animal / Q000502:physiology*; D006801:Humans; D010121:Oxytocin / Q000502:physiology*; D021641:Recognition, Psychology / Q000502:physiology*; D012377:Rodentia / Q000502:physiology* / Q000523:psychology; D012919:Social Behavior; D060756:Social Networking
chemical_list: D001127:Arginine Vasopressin; D010121:Oxytocin