title: [A case of primary T-cell central nervous system lymphoma (T-PCNSL) relevant to HTLV-I].
abstract: Primary T-cell lymphoma of the central nervous system lymphoma (T-PCNSL) is an extremely rare tumor. A human T-cell lymphoma virus type I(HTLV-I) associated adult TCL often involves the CNS during its course but disease limited to the CNS is exceptional. We report a case of a 63-year-old male with a highly malignant TCL localized in the bilateral cerebral hemispheres. The patient was HTLV-I positive but no systemic disease was detected after various examinations. We discuss the clinico-pathological features of TCL in the CNS reported in the literature including our case and compare them with those of B-cell lymphomas.
authors.affiliation: Department of Neurosurgery, National Hospital Organization Kyushu Medical Center, Japan.
authors.forename: Ai
authors.initials: A
authors.lastname: Uka
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Hamada
authors.forename: Yojiro
authors.initials: Y
authors.lastname: Akagi
authors.forename: Sei
authors.initials: S
authors.lastname: Haga
authors.forename: Tadahisa
authors.initials: T
authors.lastname: Shono
authors.forename: Shinji
authors.initials: S
authors.lastname: Nagata
authors.forename: Yoshifuku
authors.initials: Y
authors.lastname: Nakayama
mesh_terms: D000964:Antimetabolites, Antineoplastic / Q000627:therapeutic use; D001932:Brain Neoplasms / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D006801:Humans; D015459:Leukemia-Lymphoma, Adult T-Cell / Q000188:drug therapy / Q000473:pathology; D008297:Male; D008727:Methotrexate / Q000627:therapeutic use; D008875:Middle Aged
chemical_list: D000964:Antimetabolites, Antineoplastic; D008727:Methotrexate