title: Analysis of D-β-aspartyl isomers at specific sites in proteins.
abstract: Recent studies have shown that biologically uncommon D-β-aspartic acid residues accumulate in specific proteins during the aging process. However, aspartyl residues are not racemized uniformly because D-Asp appears to be confined to particular sites in these proteins. We here describe the method to identify the specific sites of D-β-aspartic acids inversion in proteins.
authors.affiliation: Research Reactor Institute, Kyoto University, Osaka, Japan. nfujii@rri.kyoto-u.ac.jp
authors.forename: Noriko
authors.initials: N
authors.lastname: Fujii
authors.forename: Norihiko
authors.initials: N
authors.lastname: Fujii
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001224:Aspartic Acid / Q000737:chemistry*; D002851:Chromatography, High Pressure Liquid; D006801:Humans; D013058:Mass Spectrometry; D011506:Proteins / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D011506:Proteins; D001224:Aspartic Acid