title: REST: a toolkit for resting-state functional magnetic resonance imaging data processing.
abstract: Resting-state fMRI (RS-fMRI) has been drawing more and more attention in recent years. However, a publicly available, systematically integrated and easy-to-use tool for RS-fMRI data processing is still lacking. We developed a toolkit for the analysis of RS-fMRI data, namely the RESting-state fMRI data analysis Toolkit (REST). REST was developed in MATLAB with graphical user interface (GUI). After data preprocessing with SPM or AFNI, a few analytic methods can be performed in REST, including functional connectivity analysis based on linear correlation, regional homogeneity, amplitude of low frequency fluctuation (ALFF), and fractional ALFF. A few additional functions were implemented in REST, including a DICOM sorter, linear trend removal, bandpass filtering, time course extraction, regression of covariates, image calculator, statistical analysis, and slice viewer (for result visualization, multiple comparison correction, etc.). REST is an open-source package and is freely available at http://www.restfmri.net.
authors.affiliation: State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University, Beijing, China.
authors.forename: Xiao-Wei
authors.initials: XW
authors.lastname: Song
authors.forename: Zhang-Ye
authors.initials: ZY
authors.lastname: Dong
authors.forename: Xiang-Yu
authors.initials: XY
authors.lastname: Long
authors.forename: Su-Fang
authors.initials: SF
authors.lastname: Li
authors.forename: Xi-Nian
authors.initials: XN
authors.lastname: Zuo
authors.forename: Chao-Zhe
authors.initials: CZ
authors.lastname: Zhu
authors.forename: Yong
authors.initials: Y
authors.lastname: He
authors.forename: Chao-Gan
authors.initials: CG
authors.lastname: Yan
authors.forename: Yu-Feng
authors.initials: YF
authors.lastname: Zang
mesh_terms: D001921:Brain / Q000503:physiopathology*; D001931:Brain Mapping; D003952:Diagnostic Imaging; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging; D008280:Magnetics; D009415:Nerve Net; D012984:Software