title: Single-incision laparoscopic total abdominal colectomy for refractory ulcerative colitis.
abstract: BACKGROUND
  A three-stage restorative proctocolectomy with ileal pouch-anal anastomosis is the treatment of choice for the particularly debilitated patient with medically refractory ulcerative colitis (UC). Laparoscopic surgery has been shown to offer several advantages over the open approach in this setting. Single-incision laparoscopic surgery is an emerging minimally invasive strategy representing a truly scarless procedure for the first surgical step, namely, the total abdominal colectomy (TAC).
  
  
  METHODS
  Nine consecutive patients with medically refractory UC underwent a single-incision laparoscopic TAC between May and October 2010. All patients were on aggressive medical therapy with corticosteroids or immunosuppressors and were selected for this approach on the basis of their body habitus and the absence of relevant comorbidities. The whole operation was performed through a single access to the abdominal cavity, placed at the ostomy site marked preoperatively.
  
  
  RESULTS
  Mean operating time was 142 ± 23 min, with an estimate blood loss of 108 ± 125 ml. No intraoperative complications or conversions to conventional laparoscopy or open surgery occurred. In all cases the postoperative course was uneventful. The return of bowel function was observed on postoperative day 1.7 ± 0.7, and patients could tolerate a solid diet on postoperative day 3 ± 0.5. The mean postoperative length of stay was 5.2 ± 1.3 days.
  
  
  CONCLUSIONS
  In our experience, a single-incision laparoscopic approach to total abdominal colectomy for refractory ulcerative colitis has been shown to be safe and feasible. Initial results suggest that this technique can lead to improvements in short-term outcomes in selected patients.
authors.affiliation: Department of Surgery, University of Chicago Medical Center, 5841 S. Maryland Ave, MC 5095, Chicago, IL 60637, USA. afichera@surgery.bsd.uchicago.edu
authors.forename: Alessandro
authors.initials: A
authors.lastname: Fichera
authors.forename: Marco
authors.initials: M
authors.lastname: Zoccali
mesh_terms: D000328:Adult; D016063:Blood Loss, Surgical; D002908:Chronic Disease; D003082:Colectomy / Q000379:methods*; D003093:Colitis, Ulcerative / Q000601:surgery*; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D010535:Laparoscopy / Q000379:methods*; D007902:Length of Stay; D008297:Male; D011300:Preoperative Care / Q000379:methods; D016896:Treatment Outcome