title: Effective wound closure with a new two-component wound closure device (Prineo™) in excisional body-contouring surgery: experience in over 200 procedures.
abstract: BACKGROUND
  In excisional body-contouring surgery the surgeon is often confronted with time-consuming closure of long wounds. Recently, a new combination of a self-adhering mesh together with a liquid 2-octyl cyanoacrylate adhesive (Prineo™; Ethicon, Inc., Somerville, NJ, USA) has been introduced to replace intracutaneous running suture.
  
  
  METHODS
  An observational study was undertaken to evaluate the efficacy of the new wound closure device in excisional body-contouring procedures between January 2008 and November 2010. Wound characteristics were recorded in a prospectively maintained database.
  
  
  RESULTS
  During the study period, 224 procedures in 180 patients were undertaken. Twenty-seven patients had two subsequent operations and four patients had three subsequent operations. Application of the new device was easy and safe and patient satisfaction with the results was generally high. However, intense local allergic reactions were seen in 4 patients (1.8%), which necessitated early removal and topical corticosteroid treatment.
  
  
  CONCLUSIONS
  Prineo™ enables the surgeon to perform a quick and smooth skin closure, especially in long incisions frequently encountered in excisional body-contouring surgery. The application is fast and easy if basic guidelines are respected. Operating time is saved by eliminating the need for time-consuming intracutaneous running sutures. Removal is easy and painless for the patient. However, there is a potential for local allergic adverse effects of which the surgeon must be aware.
authors.affiliation: Plastic, Aesthetic & Reconstructive Surgery, General Hospital Linz, Krankenhausstrasse 9, 4020, Linz, Austria. georg.huemer@maz.at
authors.forename: Georg M
authors.initials: GM
authors.lastname: Huemer
authors.forename: Manfred
authors.initials: M
authors.lastname: Schmidt
authors.forename: Gudrun H
authors.initials: GH
authors.lastname: Helml
authors.forename: Maziar
authors.initials: M
authors.lastname: Shafighi
authors.forename: Karin M
authors.initials: KM
authors.lastname: Dunst-Huemer
mesh_terms: D000328:Adult; D000368:Aged; D003487:Cyanoacrylates / Q000008:administration & dosage*; D006801:Humans; D015187:Lipectomy; D008875:Middle Aged; D017060:Patient Satisfaction; D013526:Surgical Mesh; D014014:Tissue Adhesives / Q000008:administration & dosage*; D058106:Wound Closure Techniques / Q000295:instrumentation*; D014945:Wound Healing / Q000502:physiology
chemical_list: D003487:Cyanoacrylates; D014014:Tissue Adhesives; C100832:octyl 2-cyanoacrylate