title: Feedback from area 21a influences orientation but not direction maps in the primary visual cortex of the cat.
abstract: In the monkey's visual cortex, there are two well-documented information processing streams: the dorsal motion and ventral form/color pathways. Similarly, two corresponding information streams were also found in the cat's visual cortices, and PMLS and area 21a are the gateways for distinct motion and form information processing. It has been shown that the feedback from PMLS solely modulates motion direction, but not orientation response, while the feedback from area 21a modulates form related features, such as spatial frequency dependency and neuronal oblique effect. Here, we postulate that feedback signals from higher cortical areas in the form or the motion information pathway may solely modulate the corresponding properties in neurons in the lower areas of the visual system. To examine the above hypothesis, the impact of feedback from higher area 21a on both orientation and direction maps was investigated in area 17 of the cat using intrinsic signal optical imaging. The results showed that the feedback from area 21a did not affect the amplitude and preference of direction, but did modulate orientation response in area 17, supporting the above hypothesis.
authors.affiliation: Vision Research Laboratory, Center for Brain Science Research and School of Life Sciences, Fudan University, 220 Handan Road, Shanghai 200433, China.
authors.forename: Lei
authors.initials: L
authors.lastname: Tong
authors.affiliation: Vision Research Laboratory, Center for Brain Science Research and School of Life Sciences, Fudan University, 220 Handan Road, Shanghai 200433, China.
authors.forename: Bin
authors.initials: B
authors.lastname: Zhu
authors.affiliation: Vision Research Laboratory, Center for Brain Science Research and School of Life Sciences, Fudan University, 220 Handan Road, Shanghai 200433, China.
authors.forename: Zhong
authors.initials: Z
authors.lastname: Li
authors.affiliation: Vision Research Laboratory, Center for Brain Science Research and School of Life Sciences, Fudan University, 220 Handan Road, Shanghai 200433, China.
authors.forename: Tiande
authors.initials: T
authors.lastname: Shou
authors.affiliation: Vision Research Laboratory, Center for Brain Science Research and School of Life Sciences, Fudan University, 220 Handan Road, Shanghai 200433, China. Electronic address: hongboyu@fudan.edu.cn.
authors.forename: Hongbo
authors.initials: H
authors.lastname: Yu
mesh_terms: D000818:Animals; D002415:Cats; D004562:Electrocardiography; D004569:Electroencephalography; D025461:Feedback, Physiological / Q000502:physiology*; D005260:Female; D018698:Glutamic Acid / Q000008:administration & dosage / Q000494:pharmacology; D006339:Heart Rate / Q000502:physiology; D008297:Male; D008845:Microinjections; D009949:Orientation / Q000502:physiology*; D010775:Photic Stimulation; D014793:Visual Cortex / Q000502:physiology*; D005680:gamma-Aminobutyric Acid / Q000008:administration & dosage / Q000494:pharmacology
chemical_list: D018698:Glutamic Acid; D005680:gamma-Aminobutyric Acid