title: Effect of mouth rinses with fluoride and trimetaphosphate on enamel erosion: an in vitro study.
abstract: The effect of mouth rinses containing fluoride (100 μg/ml) and sodium trimetaphosphate (TMP) on enamel erosion was evaluated in vitro. Bovine enamel blocks were subjected to erosive challenges 4 times per day for 5 min, followed by treatment with placebo, 225 μg F/ml, 100 μg F/ml, 100 μg F/ml and TMP (0.2, 0.4 and 0.6%) solutions (30 s) and storage in artificial saliva, over a duration of 5 days. TMP groups showed lower enamel wear than fluoride-only and placebo groups (p < 0.05). Addition of TMP at a TMP:NaF molar proportion between 1.24:1 and 3.72:1 to a solution containing 100 μg F/ml presented a greater protective effect under erosive conditions than a solution containing 225 μg F/ml, in the absence of TMP.
authors.affiliation: Departamento de Odontologia Infantil e Social, UNESP-Univ. Estadual Paulista, Araçatuba, Brazil.
authors.forename: M M
authors.initials: MM
authors.lastname: Manarelli
authors.forename: A E M
authors.initials: AE
authors.lastname: Vieira
authors.forename: A A
authors.initials: AA
authors.lastname: Matheus
authors.forename: K T
authors.initials: KT
authors.lastname: Sassaki
authors.forename: A C B
authors.initials: AC
authors.lastname: Delbem
mesh_terms: D000818:Animals; D002327:Cariostatic Agents / Q000627:therapeutic use*; D002417:Cattle; D003743:Dental Enamel / Q000473:pathology; D006244:Hardness; D009067:Mouthwashes / Q000737:chemistry / Q000627:therapeutic use*; D011122:Polyphosphates / Q000627:therapeutic use*; D011897:Random Allocation; D012969:Sodium Fluoride / Q000627:therapeutic use; D014077:Tooth Erosion / Q000517:prevention & control*
chemical_list: D002327:Cariostatic Agents; D009067:Mouthwashes; D011122:Polyphosphates; D012969:Sodium Fluoride; C009293:trimetaphosphoric acid