title: Resolution and mass range performance in distance-of-flight mass spectrometry with a multichannel focal-plane camera detector.
abstract: Distance-of-flight mass spectrometry (DOFMS) is a velocity-based mass-separation technique in which ions are separated in space along the plane of a spatially selective detector. In the present work, a solid-state charge-detection array, the focal-plane camera (FPC), was incorporated into the DOFMS platform. Use of the FPC with our DOFMS instrument resulted in improvements in analytical performance, usability, and versatility over a previous generation instrument that employed a microchannel-plate/phosphor DOF detector. Notably, FPC detection provided resolution improvements of at least a factor of 2, with typical DOF linewidths of 300 μm (R((fwhm)) = 1000). The merits of solid-state detection for DOFMS are evaluated, and methods to extend the DOFMS mass range are considered.
authors.affiliation: Department of Chemistry, Indiana University, Bloomington, Indiana 47405, United States.
authors.forename: Alexander W G
authors.initials: AW
authors.lastname: Graham
authors.forename: Steven J
authors.initials: SJ
authors.lastname: Ray
authors.forename: Christie G
authors.initials: CG
authors.lastname: Enke
authors.forename: Jeremy A
authors.initials: JA
authors.lastname: Felton
authors.forename: Anthony J
authors.initials: AJ
authors.lastname: Carado
authors.forename: Charles J
authors.initials: CJ
authors.lastname: Barinaga
authors.forename: David W
authors.initials: DW
authors.lastname: Koppenaal
authors.forename: Gary M
authors.initials: GM
authors.lastname: Hieftje
mesh_terms: D003300:Copper / Q000032:analysis; D007854:Lead / Q000032:analysis; D013058:Mass Spectrometry / Q000295:instrumentation* / Q000379:methods*; D014001:Tin / Q000032:analysis; D015032:Zinc / Q000032:analysis
chemical_list: C048399:brass; D007854:Lead; D014001:Tin; D003300:Copper; D015032:Zinc