title: Intermediate uveitis in a pediatric Italian population.
abstract: OBJECTIVE
  To investigate clinical data, outcome, and treatment of intermediate uveitis in children.
  
  
  METHODS
  Retrospective cohort study, including 116 children affected by intermediate uveitis.
  
  
  RESULTS
  Sixty-two percent of patients were males. Ocular involvement was bilateral in 84%. Mean age at uveitis onset was 10.3 ± 3.6 years and 12.2 ± 7 years at first visit. Ninety-seven percent were classified as having idiopathic uveitis. The incidence of ocular complications during follow-up was 0.131/eye-year. Macular edema or a marked vitreous haze at presentation may be risks factors for incident visual loss. The most frequent causes of visual loss were macular edema (64%) and cataract (21%).
  
  
  CONCLUSIONS
  Most cases are idiopathic (pars planitis); only few children presented associated systemic disease. Macular edema and severe vitritis at presentation are associated with increased risk of visual impairment. Cystoid macular edema is the main cause of visual impairment.
authors.affiliation: Department of Ophthalmology, Ocular Immunovirology Service, Sapienza University of Rome, Viale del Policlinico 155, Rome, Italy. mpparoli@tiscali.it
authors.forename: Maria Pia
authors.initials: MP
authors.lastname: Paroli
authors.forename: Giovanni
authors.initials: G
authors.lastname: Spinucci
authors.forename: Rita
authors.initials: R
authors.lastname: Monte
authors.forename: Francesca Romana
authors.initials: FR
authors.lastname: Pesci
authors.forename: Irene
authors.initials: I
authors.lastname: Abicca
authors.forename: Paola
authors.initials: P
authors.lastname: Pivetti Pezzi
mesh_terms: D000293:Adolescent; D017668:Age of Onset; D002648:Child; D005260:Female; D006801:Humans; D015994:Incidence; D007558:Italy / Q000453:epidemiology; D008269:Macular Edema / Q000150:complications; D008297:Male; D012189:Retrospective Studies; D012307:Risk Factors; D015867:Uveitis, Intermediate / Q000150:complications / Q000453:epidemiology*; D014786:Vision Disorders / Q000453:epidemiology* / Q000209:etiology