title: Enterobacter endophthalmitis: clinicomicrobiologic profile and outcomes.
abstract: OBJECTIVE
  To report the clinical presentations, antibiotic sensitivities, management, and outcomes of Enterobacter endophthalmitis.
  
  
  METHODS
  This is a retrospective, consecutive, noncomparative, interventional case series. The medical records of culture-proven Enterobacter endophthalmitis cases from the endophthalmitis registry between January 1995 and March 2006 were reviewed.
  
  
  RESULTS
  Enterobacter was the causative agent in 36 culture-proven cases. The causative event was cataract surgery in 11 and trauma in 25 patients. The presenting visual acuity was light perception in 26 eyes (72.2%). Polymicrobial infection was detected in 7 patients (19.4%). Enterobacter organisms were most sensitive to ciprofloxacin (n = 34; 94%), followed by amikacin (n = 31; 86%) and ceftazidime (n = 28; 78%). In postoperative endophthalmitis, final visual outcome of ≥20/200 was achieved in 3 patients (27%) and of ≥5/200 in 5 patients (45%). The eyes became phthisical in 3 patients (27%) and evisceration was carried out in 1 patient. In posttraumatic endophthalmitis, final visual outcome of ≥20/200 was achieved in 5 patients (20%) and of ≥5/200 in 7 patients (28%). The eyes of 11 patients (44%) became phthisical and evisceration was carried out in 1 patient.
  
  
  CONCLUSIONS
  Enterobacter organisms are mostly susceptible to ciprofloxacin, amikacin, and ceftazidime. Despite this coverage, the visual outcome is often poor.
authors.affiliation: Department of Retina and Vitreous Surgery, L. V. Prasad Eye Institute, GMR Varalakshmi Campus, Visakhapatnam, Andhra Pradesh, India. avinash@lvpei.org
authors.forename: Avinash
authors.initials: A
authors.lastname: Pathengay
authors.forename: Hemant S
authors.initials: HS
authors.lastname: Trehan
authors.forename: Annie
authors.initials: A
authors.lastname: Mathai
authors.forename: Subhadra
authors.initials: S
authors.lastname: Jalali
authors.forename: Ajit B
authors.initials: AB
authors.lastname: Majji
authors.forename: Manmath K
authors.initials: MK
authors.lastname: Das
authors.forename: Savitri
authors.initials: S
authors.lastname: Sharma
authors.forename: Taraprasad
authors.initials: T
authors.lastname: Das
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D002387:Cataract Extraction / Q000009:adverse effects; D002648:Child; D002675:Child, Preschool; D060085:Coinfection / Q000188:drug therapy / Q000382:microbiology*; D009877:Endophthalmitis / Q000188:drug therapy / Q000382:microbiology*; D004755:Enterobacteriaceae; D004756:Enterobacteriaceae Infections / Q000382:microbiology*; D005260:Female; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D012189:Retrospective Studies; D014792:Visual Acuity / Q000502:physiology; D014796:Visual Perception / Q000502:physiology; D055815:Young Adult
chemical_list: D000900:Anti-Bacterial Agents