title: [Regulation of motor behaviour].
abstract: The review is devoted to analysis of the basic links of motor behavior control systems: sensorimotor cortex, cerebellum, a red nucleus and striatum. The organization and communications of these structures and their participation in learning and memory processes are described. The synaptic neurotransmitter and nonsynaptic neuromodulatory systems innervating these structures are also described. Hierarchical synaptic networks are formed by GABA and glutamatergic systems. The nonsynaptic dopaminergic system innervates both of these structures, but carries out a modulatory function. The mesocorticolimbic dopaminergic system induces an emotional and motivational state - processes of reinforcement, and participates in realization of purposeful behavior. The nigrostriatal dopaminergic system, through triggering an endocellular signal and the processes ofphosphorylation and dephosphorylation modulates activity ofGABA and glutamatergic receptors ofdorsal striatum spiny neurons and adapted thalamocortical networks.
authors.forename: A S
authors.initials: AS
authors.lastname: Bazian
authors.forename: G A
authors.initials: GA
authors.lastname: Grigir'ian
authors.forename: M E
authors.initials: ME
authors.lastname: Ioffe
mesh_terms: D000818:Animals; D001921:Brain / Q000502:physiology*; D002540:Cerebral Cortex / Q000502:physiology*; D003342:Corpus Striatum / Q000502:physiology*; D004298:Dopamine / Q000502:physiology; D004644:Emotions / Q000502:physiology; D008568:Memory / Q000502:physiology*; D009042:Motivation / Q000502:physiology; D009043:Motor Activity / Q000502:physiology*; D017072:Neostriatum / Q000502:physiology; D009434:Neural Pathways / Q000502:physiology; D018377:Neurotransmitter Agents / Q000378:metabolism; D051381:Rats; D009435:Synaptic Transmission / Q000502:physiology
chemical_list: D018377:Neurotransmitter Agents; D004298:Dopamine