title: [Antialcoholic properties of a subalin probiotic drug].
abstract: Efficiency of a subalin probiotic drug created on the basis of live microbic cultures was investigated, at acute alcoholic intoxication developed in experimental animals. It was shown that after one time administration of this drug to animals there was no considerable influence on activity of the main enzymes of ethanol metabolism--alcohol- and aldehyde dehydrogenase both in animals with an alcoholic intoxication and without. However subalin induced considerable changes in the quantitative maintenance of acetaldehyde in blood of animals with alcoholic intoxication, which concentration decreased almost in 20 times.
authors.forename: L A
authors.initials: LA
authors.lastname: Safronova
authors.forename: T P
authors.initials: TP
authors.lastname: Kryshtab
authors.forename: L V
authors.initials: LV
authors.lastname: Avdieieva
authors.forename: N A
authors.initials: NA
authors.lastname: Stogniĭ
authors.forename: D S
authors.initials: DS
authors.lastname: Lebediev
mesh_terms: D000079:Acetaldehyde / Q000097:blood*; D000426:Alcohol Dehydrogenase / Q000097:blood*; D000435:Alcoholic Intoxication / Q000097:blood / Q000201:enzymology; D000437:Alcoholism / Q000097:blood / Q000188:drug therapy / Q000201:enzymology; D000444:Aldehyde Dehydrogenase / Q000097:blood*; D000818:Animals; D001685:Biological Factors / Q000627:therapeutic use*; D000431:Ethanol / Q000097:blood*; D008297:Male; D023421:Models, Animal; D019936:Probiotics / Q000627:therapeutic use; D051381:Rats
chemical_list: D001685:Biological Factors; C112120:subalin; D000431:Ethanol; D000426:Alcohol Dehydrogenase; D000444:Aldehyde Dehydrogenase; D000079:Acetaldehyde