title: Suzuki-Miyaura Cross-Coupling of Benzylic Bromides Under Microwave Conditions.
abstract: A procedure for benzylic Suzuki-Miyaura cross-coupling under microwave conditions has been developed. These conditions allowed for heterocyclic compounds to be coupled. Optimum conditions found were Pd(OAc)(2), JohnPhos as the catalyst and ligand, potassium carbonate as base, and DMF as the solvent. Using these conditions, a library of structurally diverse compounds was synthesized.
authors.affiliation: Core Laboratory for Neuromolecular Production, Dept. of Biomedical and Pharmaceutical Sciences, The University of Montana, Missoula, Montana 59803, United States.
authors.forename: Steven W
authors.initials: SW
authors.lastname: McDaniel
authors.forename: Charles M
authors.initials: CM
authors.lastname: Keyari
authors.forename: Kevin C
authors.initials: KC
authors.lastname: Rider
authors.forename: Nicholas R
authors.initials: NR
authors.lastname: Natale
authors.forename: Philippe
authors.initials: P
authors.lastname: Diaz