title: Using the Alberta Infant Motor Scale to early identify very low-birth-weight infants with cystic periventricular leukomalacia.
abstract: We examined whether the Alberta Infant Motor Scale (AIMS) is able to identify very low-birth-weight (VLBW) preterm infants with cystic periventricular leukomalacia (PVL) as early as 6 months of corrected age. Longitudinal follow-up AIMS assessments were done at 6, 12, and 18 months old for 35 VLBW infants with cystic PVL (cPVL(+)), 70 VLBW infants without cystic PVL (cPVL(-)), and 76 term infants (healthy controls: HC). Corrected age was used for the preterm infants. The cPVL(+) group had significantly lower prone, supine and sitting subscales at age 6, 12, and 18 months than the cPVL(-) group (all p<0.05). The cPVL(-) group showed significantly lower supine, prone, sitting, and standing subscales than the HC group only at age 6 months. At age 6 months, the areas under the receiver operator curve used to discriminate the cPVL(+) infants from cPVL(-) infants were 0.82±0.04 for prone, 0.93±0.02 for supine, 0.83±0.05 for sitting, and 0.62±0.07 for standing. The AIMS may help early identify VLBW infants with cystic PVL at age 6 months old.
authors.affiliation: Department of Pediatrics, Chei-Mei Medical Center, Tainan, Taiwan.
authors.forename: Lin-Yu
authors.initials: LY
authors.lastname: Wang
authors.forename: Yu-Lin
authors.initials: YL
authors.lastname: Wang
authors.forename: Shan-Tair
authors.initials: ST
authors.lastname: Wang
authors.forename: Chao-Ching
authors.initials: CC
authors.lastname: Huang
mesh_terms: D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D019102:Infant, Very Low Birth Weight; D007969:Leukomalacia, Periventricular / Q000175:diagnosis* / Q000503:physiopathology; D008137:Longitudinal Studies; D008297:Male; D009043:Motor Activity / Q000502:physiology*; D012307:Risk Factors