title: [Pharmacotherapy for preventing calcium containing stone formation].
abstract: Many urinary tract stones consist of calcium, and has high relapse rate. Accordingly, it is very important to prevent calcium-containing stone formation. This paper describes about effects and mechanisms for Xanthine oxidase inhibitor, citrate formulation, magnesium formulation, thiazides, vitamin B(6), extract of Quercus salicina Blume and chorei-to (medical herb) . Recent new drugs and the elucidation of new metabolic pathways may lead to the development of prevention of urolithiasis.
authors.affiliation: Department of Urology, Hamamatsu University School of Medicine, Japan.
authors.forename: Masao
authors.initials: M
authors.lastname: Nagata
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Takayama
authors.forename: Souichi
authors.initials: S
authors.lastname: Mugiya
authors.forename: Seiichiro
authors.initials: S
authors.lastname: Ohzono
mesh_terms: D000493:Allopurinol / Q000494:pharmacology* / Q000627:therapeutic use*; D000818:Animals; D002118:Calcium / Q000378:metabolism*; D002951:Citrates / Q000494:pharmacology / Q000627:therapeutic use; D004365:Drugs, Chinese Herbal / Q000494:pharmacology / Q000627:therapeutic use; D006801:Humans; D017616:Magnesium Compounds / Q000494:pharmacology / Q000627:therapeutic use; D008517:Phytotherapy; D010936:Plant Extracts / Q000494:pharmacology / Q000627:therapeutic use; D055502:Secondary Prevention; D049993:Sodium Chloride Symporter Inhibitors / Q000494:pharmacology / Q000627:therapeutic use; D014545:Urinary Calculi / Q000188:drug therapy* / Q000378:metabolism / Q000517:prevention & control*; D025101:Vitamin B 6 / Q000494:pharmacology / Q000627:therapeutic use; D014969:Xanthine Oxidase / Q000037:antagonists & inhibitors
chemical_list: D002951:Citrates; D004365:Drugs, Chinese Herbal; D017616:Magnesium Compounds; D010936:Plant Extracts; D049993:Sodium Chloride Symporter Inhibitors; C041804:choreito; D000493:Allopurinol; D025101:Vitamin B 6; D014969:Xanthine Oxidase; D002118:Calcium