title: The ten grand challenges of synthetic life.
abstract: The construction of artificial life is one of the main scientific challenges of the Synthetic Biology era. Advances in DNA synthesis and a better understanding of regulatory processes make the goal of constructing the first artificial cell a realistic possibility. This would be both a fundamental scientific milestone and a starting point of a vast range of applications, from biofuel production to drug design. However, several major issues might hamper the objective of achieving an artificial cell. From the bottom-up to the selection-based strategies, this work encompasses the ten grand challenges synthetic biologists will have to be aware of in order to cope with the task of creating life in the lab.
authors.forename: Manuel
authors.initials: M
authors.lastname: Porcar
authors.forename: Antoine
authors.initials: A
authors.lastname: Danchin
authors.forename: Victor
authors.initials: V
authors.lastname: de Lorenzo
authors.forename: Vitor A
authors.initials: VA
authors.lastname: Dos Santos
authors.forename: Natalio
authors.initials: N
authors.lastname: Krasnogor
authors.forename: Steen
authors.initials: S
authors.lastname: Rasmussen
authors.forename: Andrés
authors.initials: A
authors.lastname: Moya