title: Profile of vitiligo patients attending a training and research hospital in Central Anatolia: a retrospective study.
abstract: Clinical characteristics of vitiligo had been reported in different countries previously. This is the second report from Turkey and it is from a different region of Turkey, middle Anatolia, and a more detailed study. The age and sex of patients, onset age, duration, areas of involvement, course, clinical types and severity of the disease, family history of vitiligo, associated disorders, the values of vitamin B12, folic acid, ferritin, iron and hemoglobin, antithyroglobulin and antithyroid peroxidase antibodies and positivity of viral markers were obtained from the records of the patients retrospectively. The study involved 93 vitiligo patients with a mean age of 37.4±17.05 years. The median age of onset disease was 33 years and onset age of disease was significantly lower in women. Of the patients, 24.8% had family history. The most frequent form of vitiligo was vitiligo vulgaris. Facial involvement was the most common localization. Trunk involvement was significantly higher in women but anogenital involvement was significantly higher in men. Of the patients, 40.3% had another autoimmune disease, 19.7% of the patients had low ferritin levels, 12% had low iron levels, 9.9% had anemia, 4.9% had low vitamin B12 levels, 3.8% had low folic acid levels and 4.3% had positivity of viral markers. The age of onset and the incidence of family history were higher and sites of involvement according to sex were different from the published work. The knowledge of clinical characteristics, course and associated conditions of vitiligo may improve the approach of dermatologists to vitiligo patients.
authors.affiliation: Ankara Numune Education and Research Hospital, 2nd Dermatology Clinic Department of Epidemiology, Gülhane Military Medical Academy, Ankara, Turkey. muzeyyengonul@yahoo.com
authors.forename: Müzeyyen
authors.initials: M
authors.lastname: Gönül
authors.forename: Seray K
authors.initials: SK
authors.lastname: Cakmak
authors.forename: Deniz
authors.initials: D
authors.lastname: Oğuz
authors.forename: Ulker
authors.initials: U
authors.lastname: Gül
authors.forename: Selim
authors.initials: S
authors.lastname: Kiliç
mesh_terms: D000293:Adolescent; D000328:Adult; D017668:Age of Onset; D000368:Aged; D001323:Autoantibodies / Q000097:blood; D001327:Autoimmune Diseases / Q000097:blood / Q000453:epidemiology; D002648:Child; D015897:Comorbidity; D005260:Female; D005293:Ferritins / Q000097:blood; D005492:Folic Acid / Q000097:blood; D006454:Hemoglobins / Q000032:analysis; D006784:Hospitals, Teaching; D006801:Humans; D015994:Incidence; D007453:Iodide Peroxidase / Q000276:immunology; D007501:Iron / Q000097:blood; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012189:Retrospective Studies; D012720:Severity of Illness Index; D014421:Turkey / Q000453:epidemiology; D014805:Vitamin B 12 / Q000097:blood; D014820:Vitiligo / Q000097:blood* / Q000175:diagnosis* / Q000453:epidemiology; D055815:Young Adult
chemical_list: D001323:Autoantibodies; D006454:Hemoglobins; C006606:anti-thyroglobulin; D005293:Ferritins; D005492:Folic Acid; D007501:Iron; D007453:Iodide Peroxidase; D014805:Vitamin B 12