title: Tissue polarity: PCP inheritance ensured by selective mitotic endocytosis.
abstract: Recent findings report the selective internalization of core planar cell polarity components during mitosis followed by cell-non-autonomous polarized recycling. This novel mechanistic model explains how tissue polarity is inherited in daughter cells of proliferative tissue.
authors.affiliation: CNRS, UMR 6061, Institut Génétique et Développement de Rennes, Université Rennes 1, UEB, IFR 140, F-35043 Rennes, France.
authors.forename: Nabila
authors.initials: N
authors.lastname: Founounou
authors.forename: Roland
authors.initials: R
authors.lastname: Le Borgne
mesh_terms: D000818:Animals; D016764:Cell Polarity / Q000235:genetics / Q000502:physiology*; D048749:Cytokinesis / Q000502:physiology; D004330:Drosophila / Q000166:cytology / Q000235:genetics; D004705:Endocytosis; D011992:Endosomes / Q000502:physiology; D051157:Frizzled Receptors / Q000235:genetics / Q000378:metabolism / Q000502:physiology; D051379:Mice; D008822:Mice, Transgenic; D008938:Mitosis / Q000235:genetics / Q000502:physiology*; D009154:Mutation; D009419:Nerve Tissue Proteins / Q000235:genetics / Q000378:metabolism / Q000502:physiology; D043562:Receptors, G-Protein-Coupled / Q000235:genetics / Q000378:metabolism / Q000502:physiology; D012867:Skin / Q000166:cytology; D013234:Stem Cells / Q000166:cytology / Q000502:physiology
chemical_list: C117380:Celsr1 protein, mouse; D051157:Frizzled Receptors; C111048:Fzd6 protein, mouse; C431577:Ltap protein, mouse; D009419:Nerve Tissue Proteins; D043562:Receptors, G-Protein-Coupled