title: [Prognostic value of the molecular markers ICAM-1 and C-JUN in patients with lung cancer].
abstract: Many of the clinical and fundamental scientific studies are directed to the investigation of the prognostic factors in patients with lung cancer. Many molecular factors are known to have independent prognostic significance and although these factors are not routinely used in the clinical practice, they may play an important role in the future.
  
  
  METHODS
  The study included 122 patients with non-small cell lung cancer. We examined the expression of ICAM-1 and C-Jun.
  
  
  RESULTS
  The median time of survival for the group with poor expression of C-Jun was 39 months, and 26 months for the group with strong expresssion. The median time of survival for the group with poor expression of ICAM-1 was 51 months and only 9 months for the group with strong expresssion.
  
  
  CONCLUSIONS
  The increased levels of ICAM-1 and C-Jun are negative prognostic factors for the patients with non-small cell lung cancer.
authors.forename: A
authors.initials: A
authors.lastname: Uchikov
authors.forename: I
authors.initials: I
authors.lastname: Dimitrov
authors.forename: B
authors.initials: B
authors.lastname: Hadjiev
authors.forename: G
authors.initials: G
authors.lastname: Prisadov
authors.forename: E
authors.initials: E
authors.lastname: Uchikova
authors.forename: P
authors.initials: P
authors.lastname: Ganchevska
mesh_terms: D000328:Adult; D000368:Aged; D002289:Carcinoma, Non-Small-Cell Lung / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D018799:Intercellular Adhesion Molecule-1; D008168:Lung / Q000473:pathology / Q000601:surgery; D008175:Lung Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D016755:Proto-Oncogene Proteins c-jun; D016019:Survival Analysis
chemical_list: D016755:Proto-Oncogene Proteins c-jun; D018799:Intercellular Adhesion Molecule-1