title: [The expressions of alpha-enolase in the nasopharyngeal cancer tissue].
abstract: OBJECTIVE
  To study the meaning of expressions of ENO1 in the nasopharyngeal cancer tissue.
  
  
  METHODS
  By using SP immunohistochemical methods.
  
  
  RESULTS
  The positive expressions for ENO1 were 60.0% in the nasopharyngeal cancer tissues,significantly higher than that (27.5%, 11/40) of in inflammatory nasopharyngeal mucosa (P<0.05). The positive expression rate of ENO1 protein in stage T1 + T2 + T3 was higher than that of in patients with T4 (chi2 = 11.424, P<0.05). But there was no significant relationship between expression of ENO1 and lymph node metastasis and postradiotherapy distant metastasis (P>0.05).
  
  
  CONCLUSIONS
  The results show that ENO1 over expression may play a important role in cell proliferation and canceration of nasopharyngeal cancer.
authors.affiliation: Department of Otorhinolaryngology Head and Neck Surgery, Zhujiang Hospital, South Medical University, Guangzhou, 510282, China.
authors.forename: Chao
authors.initials: C
authors.lastname: Cheng
authors.forename: Xiaobin
authors.initials: X
authors.lastname: Long
authors.forename: Xin
authors.initials: X
authors.lastname: Li
authors.forename: Minqiang
authors.initials: M
authors.lastname: Xie
authors.forename: Menghe
authors.initials: M
authors.lastname: Guo
mesh_terms: D000328:Adult; D000368:Aged; D014408:Biomarkers, Tumor / Q000378:metabolism*; D002277:Carcinoma; D016022:Case-Control Studies; D004268:DNA-Binding Proteins / Q000378:metabolism*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D000077274:Nasopharyngeal Carcinoma; D009303:Nasopharyngeal Neoplasms / Q000378:metabolism* / Q000473:pathology; D009361:Neoplasm Invasiveness / Q000473:pathology; D009367:Neoplasm Staging; D010751:Phosphopyruvate Hydratase / Q000378:metabolism*; D025521:Tumor Suppressor Proteins / Q000378:metabolism*; D055815:Young Adult
chemical_list: D014408:Biomarkers, Tumor; D004268:DNA-Binding Proteins; D025521:Tumor Suppressor Proteins; C095157:ENO1 protein, human; D010751:Phosphopyruvate Hydratase