title: [Perfluorocarbon liquids and vitreoretinal surgery in 2011].
abstract: Perfluorocarbon liquids (PFCLs) are one of the most innovative recent tools for vitreoretinal surgery. PFCLs are characterized by their number of carbon atoms, which has an impact on the density, viscosity, surface tension, vapor pressure, the boiling point, and the refraction index. PFCLs are routinely used because of their high gravity (double that of water) and their low viscosity. Furthermore, they are immiscible in water, optically clear with refraction indices similar to that of water, allowing visualization of an interface between the PFCL and saline. The use of intravitreally injected liquid PFCLs as adjunctive agents to vitreoretinal surgery plays an important role in facilitating retinal reattachment, especially in cases of giant retinal tear, trauma, and/or proliferative vitreoretinopathy. PFCLs are also used as intraoperative instruments to re-establish intraocular volume, assist in separating membranes adherent to the retina (in proliferative diabetic retinopathy, for example), and manage the dislocated crystalline lens and intraocular lens.
authors.affiliation: Clinique universitaire d'ophtalmologie, université Joseph-Fourier-Grenoble-1, CHU de Grenoble, BP 217, 38043 Grenoble cedex 09, France. cchiquet@chu-grenoble.fr
authors.forename: C
authors.initials: C
authors.lastname: Chiquet
authors.forename: G
authors.initials: G
authors.lastname: Thuret
mesh_terms: D055808:Drug Discovery / Q000266:history / Q000639:trends; D004345:Drug Industry / Q000266:history / Q000639:trends; D005466:Fluorocarbons / Q000737:chemistry / Q000627:therapeutic use*; D049674:History, 21st Century; D006801:Humans; D008954:Models, Biological; D011182:Postoperative Care / Q000379:methods / Q000639:trends; D012996:Solutions; D013500:Surface Tension; D013997:Time Factors; D057586:Vitreoretinal Surgery / Q000266:history / Q000379:methods* / Q000534:rehabilitation / Q000639:trends*
chemical_list: D005466:Fluorocarbons; D012996:Solutions