title: [Clinical epidemiologic features in children allergic to Dermatophagoides pteronyssinus].
abstract: OBJECTIVE
  To investigate the prevalence of Dermatophagoides pteronyssinus in children allergic diseases in Hangzhou and its surrounding areas.
  
  
  METHODS
  Western blotting was used to detect the serum antibody for 9 422 children who were admitted due to clinically suspected allergic diseases. Clinical epidemiological features were analyzed for those with total IgE>100 IU/ml and Dermatophagoides pteronyssinus-specific IgE > or = 0.35 IU/ml.
  
  
  RESULTS
  The prevalence of Dermatophagoides pteronyssinus in children with allergic diseases was 41.2% (3 878/9 422). The most common symptoms were allergic rhinitis [47.8%(1852/3 878)] and asthma [18.5%(716/3 878)]. The allergic diseases were most prevalent in July, August and October. The diseases were more prevalent in children over 3 years old and above. more in males [68.8% (2668/3878)] than females [31.2% (1210/3878)].
  
  
  CONCLUSIONS
  Data suggest that Dermatophagoides pteronyssinus is an important allergen causing allergic diseases in children in Hangzhou.
authors.affiliation: The Children's Hospital Affiliated to Zhejiang University School of Medicine, Hangzhou 310003, China.
authors.forename: Fang
authors.initials: F
authors.lastname: Ye
authors.forename: Jian-feng
authors.initials: JF
authors.lastname: Liang
authors.forename: Jin-tu
authors.initials: JT
authors.lastname: Lou
mesh_terms: D000293:Adolescent; D000485:Allergens / Q000097:blood / Q000276:immunology; D000818:Animals; D002648:Child; D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D040002:Dermatophagoides pteronyssinus / Q000276:immunology*; D005260:Female; D006801:Humans; D006967:Hypersensitivity / Q000453:epidemiology* / Q000276:immunology / Q000469:parasitology*; D007223:Infant; D007231:Infant, Newborn; D008297:Male
chemical_list: D000485:Allergens