title: Clinical and pathological analysis of hepatic artery aneurysm in a patient with systemic lupus erythematosus: report of a case.
abstract: A hepatic artery aneurysm is an unusual but life-threatening hepatobiliary complication occurring in patients with systemic lupus erythematosus (SLE), and early diagnosis and treatment of this complication are essential. A 31-year-old man with SLE presented with recurring epigastric pain and jaundice for 2 months; he was diagnosed with choledocholithiasis and underwent surgery. Hemobilia was found intraoperatively, and two hepatic artery aneurysms were identified in the left lateral lobe during postoperative arteriography. Major hemobilia occurred 6 days after the operation, and the patient was immediately treated with selective embolization of the hepatic artery. However, the major hemobilia recurred 2 days later, and he was treated with a left lateral lobectomy and ligation of the proximal hepatic artery. The patient recovered uneventfully and is in good condition. A histological analysis revealed small- and medium-sized arteritis as well as hepatic artery aneurysm. Systemic lupus erythematosus complicated by a hepatic artery aneurysm should be considered in the differential diagnosis of patients showing symptoms of abdominal pain, jaundice, or gastrointestinal bleeding.
authors.affiliation: Department of Hepato-Pancreato-Biliary Surgery, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, Guangdong Province, PR China.
authors.forename: Chao
authors.initials: C
authors.lastname: Liu
authors.forename: Qi-Bin
authors.initials: QB
authors.lastname: Tang
authors.forename: Hong
authors.initials: H
authors.lastname: Zeng
authors.forename: Xian-Huan
authors.initials: XH
authors.lastname: Yu
authors.forename: Lei-Bo
authors.initials: LB
authors.lastname: Xu
authors.forename: Yong
authors.initials: Y
authors.lastname: Li
mesh_terms: D000328:Adult; D000783:Aneurysm / Q000175:diagnosis* / Q000628:therapy*; D001707:Biopsy, Needle; D002760:Cholangiopancreatography, Endoscopic Retrograde / Q000379:methods; D004621:Embolization, Therapeutic / Q000009:adverse effects / Q000379:methods; D005500:Follow-Up Studies; D006431:Hemobilia / Q000209:etiology / Q000601:surgery*; D006498:Hepatectomy / Q000379:methods*; D006499:Hepatic Artery; D006801:Humans; D007150:Immunohistochemistry; D008107:Liver Diseases / Q000175:diagnosis / Q000601:surgery; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000175:diagnosis; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D018570:Risk Assessment; D012720:Severity of Illness Index; D016896:Treatment Outcome