title: [Association of insulin resistance to different anthropometric measures and cardiovascular risk factors in a non-diabetic population].
abstract: OBJECTIVE
  Insulin resistance (IR) has been directly related to obesity, particularly central obesity, and to other cardiovascular risk factors (CVRFs). Direct IR quantification is difficult in clinical practice, and indirect methods such as HOMA (homeostasis model assessment) have therefore been developed. The aim of this study was to assess the association of IR, as measured by HOMA, with different anthropometric measures and some CVRFs.
  
  
  METHODS
  A cross-sectional, observational study was carried out in a general population sample older than 18 years in the province of Albacete, Spain. Sample size was 678 subjects. Participants completed a survey and underwent physical examinations and laboratory tests. Obesity measures included body mass index, waist perimeter, and sagittal abdominal diameter. Data analysis was performed using SPSS 15.0 software.
  
  
  RESULTS
  Mean values of obesity measures were higher in males as compared to females and increased with age. IR prevalence was 39.8%. All assessed anthropometric measures, decreased HDL (high density lipoprotein) cholesterol and increased non-HDL cholesterol were independently associated to the risk of IR.
  
  
  CONCLUSIONS
  A clear association exists between different anthropometrical measures and IR in the general population. There is also an association between lipid profile cahnges and the risk of experiencing IR.
authors.affiliation: Centro de Salud Zona 4, Albacete, España. martasimr@gmail.com
authors.forename: Marta
authors.initials: M
authors.lastname: Simarro Rueda
authors.forename: Julio A
authors.initials: JA
authors.lastname: Carbayo Herencia
authors.forename: Javier
authors.initials: J
authors.lastname: Massó Orozco
authors.forename: Luis Miguel
authors.initials: LM
authors.lastname: Artigao Rodenas
authors.forename: Lucinio
authors.initials: L
authors.lastname: Carrión Valero
authors.forename: Juan Antonio
authors.initials: JA
authors.lastname: Divisón Garrote
authors.forename: Pilar
authors.initials: P
authors.lastname: Torres Moreno
authors.forename: Juan
authors.initials: J
authors.lastname: López Abril
authors.forename: Abel J
authors.initials: AJ
authors.lastname: Herrero Hernández
authors.forename: Francisca
authors.initials: F
authors.lastname: Molina Escribano
mesh_terms: D015992:Body Mass Index; D002318:Cardiovascular Diseases / Q000453:epidemiology*; D003430:Cross-Sectional Studies; D003920:Diabetes Mellitus; D005260:Female; D006801:Humans; D007333:Insulin Resistance; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012307:Risk Factors; D055105:Waist Circumference