title: Where will new neuroscience therapies come from?
abstract: The challenges of developing drugs for central nervous system disorders have led some major companies to reduce or discontinue investment in the field, even though the unmet medical need is substantial. How can the wealth of basic research knowledge in neuroscience be successfully translated into new therapies?
authors.affiliation: Neuroscience and Ophthalmology Research at Merck 351 Sumneytown Pike, North Wales, Pennsylvania 19454, USA. darryle_schoepp@merck.com
authors.forename: Darryle D
authors.initials: DD
authors.lastname: Schoepp
mesh_terms: D000818:Animals; D002493:Central Nervous System Diseases / Q000188:drug therapy* / Q000378:metabolism; D002986:Clinical Trials as Topic / Q000639:trends; D055808:Drug Discovery / Q000639:trends*; D006801:Humans; D009422:Nervous System Diseases / Q000188:drug therapy / Q000378:metabolism; D009488:Neurosciences / Q000639:trends*; D004364:Pharmaceutical Preparations / Q000008:administration & dosage / Q000378:metabolism
chemical_list: D004364:Pharmaceutical Preparations