title: Transplant glomerulopathy: it's not always about chronic rejection.
abstract: Transplant glomerulopathy (TG) is a morphologic lesion of renal allografts characterized by duplication of the glomerular basement membrane and is widely accepted as a manifestation of chronic antibody-mediated rejection (AMR). However, TG is not specific for chronic AMR, and this pattern of injury may result from a number of disease processes affecting the glomerular endothelium. Baid-Agrawal and co-workers consider three different, but not mutually exclusive, processes that can produce morphologic lesions of TG: chronic AMR, hepatitis C, and thrombotic microangiopathy.
authors.forename: Mark
authors.initials: M
authors.lastname: Haas
mesh_terms: D006084:Graft Rejection / Q000150:complications*; D006526:Hepatitis C / Q000150:complications*; D006801:Humans; D007674:Kidney Diseases / Q000209:etiology*; D007678:Kidney Glomerulus / Q000473:pathology*; D016030:Kidney Transplantation / Q000009:adverse effects*; D057049:Thrombotic Microangiopathies / Q000150:complications*