title: [Imperative partial nephrectomy for renal cell carcinoma: oncological and functional results].
abstract: OBJECTIVE
  To study oncological results and functional results after partial nephrectomy in imperative indication for the treatment of renal cell carcinoma.
  
  
  METHODS
  From January 1990 to December 2009, 65 partial nephrectomies in 61 patients were performed in imperative indication for renal cell carcinoma.
  
  
  RESULTS
  The mean age of patients was 59.3 years. The mean follow-up was 47.4 months. The tumours were asymptomatic in 87.5%. The average tumour diameter was 4.3 cm. Twenty-nine percent of patients relapsed after a mean time of 27.4 months. The morbidity was 38.5%. Preoperative and endpoint serum creatinine and renal clearance were respectively 119 μmol/L and 63.1 mL/min versus 137 μmol/L and 50.9 mL/min (P=0.0003; 0.0002). Overall survival at one, three, five and ten years was 98.4%, 91.2%, 91.2% and 51.9%.
  
  
  CONCLUSIONS
  Partial nephrectomy in imperative indication for renal cell carcinoma has helped preserve renal function but has a significant morbidity and recurrence rate.
authors.affiliation: Clinique urologique, CHU de Nantes, place Alexis-Ricordeau, Nantes, France. adrien.lecouteux@gmail.com
authors.forename: A
authors.initials: A
authors.lastname: Lecouteux
authors.forename: J
authors.initials: J
authors.lastname: Rigaud
authors.forename: P
authors.initials: P
authors.lastname: Glemain
authors.forename: L
authors.initials: L
authors.lastname: Le Normand
authors.forename: O
authors.initials: O
authors.lastname: Bouchot
authors.forename: G
authors.initials: G
authors.lastname: Karam
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002292:Carcinoma, Renal Cell / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007680:Kidney Neoplasms / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009392:Nephrectomy / Q000379:methods*; D012189:Retrospective Studies; D016896:Treatment Outcome; D055815:Young Adult