title: An oxidative cross-dehydrogenative-coupling reaction in water using molecular oxygen as the oxidant: vanadium catalyzed indolation of tetrahydroisoquinolines.
abstract: An aerobic oxidative cross-dehydrogenative coupling reaction between sp(3) C-H and sp(2) C-H bonds is developed by employing a vanadium catalyst (10 mol%) in an aqueous medium using molecular oxygen as the oxidant. This environmentally benign strategy exhibits larger substrate scope and shows high regioselectivity.
authors.affiliation: Department of Organic Chemistry, Indian Institute of Science, Bangalore 560 012, Karnataka, India.
authors.forename: Kaliyamoorthy
authors.initials: K
authors.lastname: Alagiri
authors.forename: Guralamatta Siddappa Ravi
authors.initials: GS
authors.lastname: Kumara
authors.forename: Kandikere Ramaiah
authors.initials: KR
authors.lastname: Prabhu