title: [Ovarian ginandroblastoma as a transcesarean incidental finding. A case report and literature review].
abstract: The gynandroblastoma is an extremely rare sexual cord stromal tumor, which contains both male and female elements, characterized by Sertoli or Leydig cells and granulose cells. We describe an ovarian gynandroblastoma in a 28 year-old female patient, found accidentally during a cesarean section operation. There is only one reported case in world literature occurring in a pregnant woman. The principal component we found was adult granulose cells, with a microfollicular pattern, and the presence of luteinized cells in some areas; besides we found the presence of well differentiated Sertoli cells elements, in addition to Leydig cells groups, in over 10% of the tumoral surface. Inmunohistochemical stainings were performed: citokeratin, which resulted positive in Sertoli cells and negative in granulose cells; and inhibin, which was positive in both components showing its mixed origin.
authors.affiliation: Servicio de Anatomía Patológica y Citopatología, Hospital Universitario Dr. José Eleuterio González, Universidad Autónoma de Nuevo León, Monterrey, México. bpositivo66@hotmail.com
authors.forename: Gabriela Sofía
authors.initials: GS
authors.lastname: Gómez-Macías
authors.forename: Raquel
authors.initials: R
authors.lastname: Garza-Guajardo
authors.forename: Juan Pablo
authors.initials: JP
authors.lastname: Flores-Gutiérrez
authors.forename: Oscar
authors.initials: O
authors.lastname: Vidal-Gutiérrez
authors.forename: Oralia
authors.initials: O
authors.lastname: Barboza-Quintana
mesh_terms: D000328:Adult; D014408:Biomarkers, Tumor / Q000032:analysis; D002585:Cesarean Section; D005260:Female; D006107:Granulosa Cells / Q000473:pathology; D006801:Humans; D033162:Incidental Findings; D007265:Inhibins / Q000032:analysis; D007633:Keratins / Q000032:analysis; D007985:Leydig Cells / Q000473:pathology; D008297:Male; D009363:Neoplasm Proteins / Q000032:analysis; D010051:Ovarian Neoplasms / Q000737:chemistry / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000175:diagnosis* / Q000378:metabolism / Q000473:pathology / Q000601:surgery; D012708:Sertoli Cells / Q000473:pathology; D018312:Sex Cord-Gonadal Stromal Tumors / Q000737:chemistry / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery
chemical_list: D014408:Biomarkers, Tumor; D009363:Neoplasm Proteins; D007265:Inhibins; D007633:Keratins