title: [Study on four natures of six flavor Chinese materia medica as rhizoma coptidis and radix aconiti lateralis praeparata etc].
abstract: OBJECTIVE
  To study on four natures of six flavor Chinese meteria medica as rhizoma coptidis, radix scutellariae, radix aconiti lateralis praeparata, rhizoma zingiberis, rhizoma dioscoreae and radix et rhizoma glycyrrhizae.
  
  
  METHODS
  To determine the biological enthalpy of extracts of Chinese meteria medica, rats' metabolites and excrement after feeding the extract of medicines and the standard substance of basic by the oxygen bomb calorimeter.
  
  
  RESULTS
  The biological enthalpy of rhizoma coptidis, radix scutellariae, radix aconiti lateralis praeparata, rhizoma zingiberis, rhizoma dioscoreae and radix et rhizoma glycyrrhizae were (3006.02 +/- 201.51)J/g, (1592.41 +/- 404.41)J/g, -(433.10 +/- 64.43)J/g, -(665.72 +/- 198.59)J/g, -(18.41 +/- 50.08)J/g, (29.55 +/- 55.13)J/g respectively. According to the results, rhizoma coptidis and radix scutellariae showed cold properties, whereas those of radix aconiti lateralis praeparata and rhizoma zingiberis were opposite as well as rhizoma dioscoreae and radix et rhizoma glycyrrhizae were neutral drugs.
  
  
  CONCLUSIONS
  The four natures of Chinese meteria medica presente in traditional Chinese pharmacology could be determined by the mathematical model of four natures.
authors.affiliation: Department of Pharmaceutics, Hunan University of Traditional Chinese Medicine, Changsha 410208, China. tangyu1015@163.com
authors.forename: Yu
authors.initials: Y
authors.lastname: Tang
authors.forename: Ping-An
authors.initials: PA
authors.lastname: Liu
authors.forename: Yun
authors.initials: Y
authors.lastname: Qiu
authors.forename: Jing
authors.initials: J
authors.lastname: Tian
authors.forename: Ji-Lian
authors.initials: JL
authors.lastname: Shi
authors.forename: Wen-Long
authors.initials: WL
authors.lastname: Liu
authors.forename: Jian-Sheng
authors.initials: JS
authors.lastname: Guo
authors.forename: Fu-Yuan
authors.initials: FY
authors.lastname: He
mesh_terms: D031841:Aconitum / Q000737:chemistry; D000465:Algorithms; D000818:Animals; D001835:Body Weight; D039323:Coptis / Q000737:chemistry; D004365:Drugs, Chinese Herbal / Q000737:chemistry* / Q000494:pharmacology; D008516:Medicine, Chinese Traditional; D008962:Models, Theoretical; D010946:Plants, Medicinal / Q000737:chemistry*; D051381:Rats; D017207:Rats, Sprague-Dawley; D031364:Scutellaria baicalensis / Q000737:chemistry; D013696:Temperature; D013816:Thermodynamics
chemical_list: D004365:Drugs, Chinese Herbal