title: Endodontic surgery failure: SEM analysis of root-end filling.
abstract: This study investigated the quality of root-end filling in cases of periapical lesions persisting after endodontic surgery. Ten patients requiring extraction of an endodontically treated tooth were included. The root-ends of extracted teeth were examined by scanning electron microscopy. Defects at the interface between the root-end filling and cavity margin were classified as ideal, imperfect (some marginal disruption) or inadequate (continuous marginal disruption involving >30% of the interface). Four cases were scored as imperfect, and six were scored as inadequate. A defective apical seal could favour continuous leakage of surviving bacteria and their by-products from the infected root canal system to periapical tissues, thereby sustaining inflammation.
authors.affiliation: Department of Health Technologies, IRCCS Galeazzi Orthopaedic Institute, University of Milan, Milan, Italy.
authors.forename: Silvio
authors.initials: S
authors.lastname: Taschieri
authors.forename: Raphael
authors.initials: R
authors.lastname: Bettach
authors.forename: Alessandra
authors.initials: A
authors.lastname: Lolato
authors.forename: Laura
authors.initials: L
authors.lastname: Moneghini
authors.forename: Massimo Del
authors.initials: MD
authors.lastname: Fabbro
mesh_terms: D003763:Dental Leakage / Q000209:etiology; D019232:Dental Restoration Failure / Q000706:statistics & numerical data*; D006801:Humans; D008855:Microscopy, Electron, Scanning; D019815:Oxalic Acid; D011446:Prospective Studies; D012184:Retrograde Obturation / Q000009:adverse effects*; D012387:Root Canal Filling Materials; D014081:Tooth Extraction; D017211:Treatment Failure
chemical_list: D012387:Root Canal Filling Materials; C474198:SuperSeal; D019815:Oxalic Acid