title: Silver-catalysed intramolecular cyclisation of 2-alkynylacetophenones and 3-acetyl-2-alkynylpyridines in the presence of ammonia.
abstract: Silver-catalysed/microwave-assisted domino reactions of 2-alkynyl-acetophenones and 3-acetyl-2-alkynylpyridines in the presence of ammonia are widely described. In most cases the reaction give a mixture of the imino- and carbo-cyclisation products, with a general preference for the former. A plausible mechanism is proposed and the dual activity of silver salts is supported by NMR experiments.
authors.affiliation: DISMAB-Sezione di Chimica Organica A. Marchesini, Università degli Studi di Milano, Milano, Italia.
authors.forename: Monica
authors.initials: M
authors.lastname: Dell'Acqua
authors.forename: Giorgio
authors.initials: G
authors.lastname: Abbiati
authors.forename: Antonio
authors.initials: A
authors.lastname: Arcadi
authors.forename: Elisabetta
authors.initials: E
authors.lastname: Rossi