title: [Changes in the chromatin structure of lymphoid cells under the influence of low-intensity extremely high-frequency electromagnetic radiation against the background of inflammatory process].
abstract: Using the alkaline single cell gel electrophoresis technique (comet assay), changes in chromatin structure of peripheral blood leukocytes and peritoneal neutrophils have been studied in mice exposed to low-intensity extremely high-frequency electromagnetic radiation (42.2 GHz, 0.1 mW/cm2, 20 min at 1 h after induction of inflammation) against the background of the systemic inflammatory process. It was revealed that the exposure of mice with the developing inflammation leads to a pronounced decrease in the level of DNA damage to peripheral blood leukocytes and peritoneal neutrophils. It is supposed that the changes in the chromatin structure of lymphoid cells have a genoprotective character in the inflammatory process and can underlie the mechanisms of realization of antiinflammatory effects of the electromagnetic radiation.
authors.forename: A B
authors.initials: AB
authors.lastname: Gapeev
authors.forename: N A
authors.initials: NA
authors.lastname: Romanova
authors.forename: N K
authors.initials: NK
authors.lastname: Chemeris
mesh_terms: D000818:Animals; D002843:Chromatin / Q000378:metabolism*; D007249:Inflammation / Q000139:chemically induced / Q000378:metabolism / Q000628:therapy; D008214:Lymphocytes / Q000378:metabolism*; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D008872:Microwaves; D009504:Neutrophils / Q000378:metabolism; D010538:Peritonitis / Q000139:chemically induced / Q000378:metabolism* / Q000628:therapy; D012780:Short-Wave Therapy
chemical_list: D002843:Chromatin