title: Water-soluble prodrug of antimicrotubule agent plinabulin: effective strategy with click chemistry.
authors.affiliation: School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo, Japan.
authors.forename: Fumika
authors.initials: F
authors.lastname: Yakushiji
authors.forename: Hironari
authors.initials: H
authors.lastname: Tanaka
authors.forename: Kyohei
authors.initials: K
authors.lastname: Muguruma
authors.forename: Takahiro
authors.initials: T
authors.lastname: Iwahashi
authors.forename: Yuri
authors.initials: Y
authors.lastname: Yamazaki
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Hayashi
mesh_terms: D000970:Antineoplastic Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D043182:Carboxylesterase / Q000378:metabolism*; D057930:Click Chemistry; D054659:Diketopiperazines / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D006868:Hydrolysis; D015394:Molecular Structure; D011355:Prodrugs / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D012995:Solubility; D014867:Water
chemical_list: D000970:Antineoplastic Agents; D054659:Diketopiperazines; C514351:NPI 2358; D011355:Prodrugs; C119340:phenylahistin; D014867:Water; D043182:Carboxylesterase