title: Benign gastrointestinal mesenchymal BUMPS: a brief review of some spindle cell polyps with published names.
abstract: BACKGROUND
  There are several benign, predominantly spindle cell, mesenchymal proliferations involving the mucosa and/or submucosa in the gut, which present as polyps and pathologists see as polypectomy specimens. These include perineuriomas, Schwann cell nodules, ganglioneuromas, leiomyomas of the muscularis mucosae, inflammatory fibroid polyps, and granular cell tumors.
  
  
  OBJECTIVE
  To evaluate these mesenchymal polyps for their morphologic, immunohistochemical, ultrastructural, and molecular characteristics and to determine some of their associations.
  
  
  METHODS
  Personal observations based on years of analyzing endoscopic biopsies and a review of the world's literature.
  
  
  CONCLUSIONS
  These polyps do surface every so often. There is significant literature covering inflammatory fibroid polyps and granular cell tumors, but there is little literature about the other entities.
authors.affiliation: Department of Pathology, University of Michigan Hospital, Ann Arbor, MI 48109, USA.
authors.forename: Ahren C
authors.initials: AC
authors.lastname: Rittershaus
authors.forename: Henry D
authors.initials: HD
authors.lastname: Appelman
mesh_terms: D005729:Ganglioneuroma / Q000473:pathology; D005770:Gastrointestinal Neoplasms / Q000473:pathology*; D016586:Granular Cell Tumor / Q000473:pathology; D006222:Hamartoma / Q000473:pathology; D006801:Humans; D007417:Intestinal Polyps / Q000473:pathology; D007889:Leiomyoma / Q000473:pathology; D018317:Nerve Sheath Neoplasms / Q000473:pathology; D011127:Polyps / Q000473:pathology*; D012583:Schwann Cells / Q000473:pathology