title: [Allergy to materials used in dental procedures].
abstract: OBJECTIVE
  To provide a review of the literature regarding the pathological effects of material used in clinical dentistry.
  
  
  METHODS
  PubMed search was performed using the key words: dental biomaterial, odontologic toxicity, odontologic allergy, dental allergens, dental resins.
  
  
  METHODS
  Articles were selected based on their relevance to this topic.
  
  
  RESULTS
  The biomaterials used in orthodontic or dental treatment may lead to alterations of greater biological importance in susceptible or sensitized individuals, and may be able to alter the functions of cells in the mouth, including dentinogenesis and tissue repair; toxicity and mutagenicity have been observed. Some of them release potential antigens or allergens capable of inducing immune or immediate and delayed allergic reactions of diverse severity and extension, which may include extraoral damage.
  
  
  CONCLUSIONS
  The number of patients with pathology originated by dental materials has increased. The scarce knowledge about it delays diagnosis. The study of biomaterials used in odontologic procedures and its harmful effect must be encouraged, as well as its pathological manifestations which require more clinical investigation and diffusion, with the aim to give more and better information to dentists, family and allergy physicians so that they can provide prompt and successful care.
authors.affiliation: Servicio de Alergia e Inmunología Clínica, Hospital General de México, México, DF, Mexico. valenciazavala@hotmail.com.
authors.forename: Martha Patricia
authors.initials: MP
authors.lastname: Valencia Zavala
authors.forename: Manuel Anastacio
authors.initials: MA
authors.lastname: Sánchez Olivas
authors.forename: Guillermo
authors.initials: G
authors.lastname: Velázquez Sámano
authors.forename: Guadalupe
authors.initials: G
authors.lastname: Sepúlveda
authors.forename: Iveth
authors.initials: I
authors.lastname: Flores
authors.forename: Andrea
authors.initials: A
authors.lastname: Velazco
authors.forename: Gloria Bertha
authors.initials: GB
authors.lastname: Vega Robledo
mesh_terms: D000485:Allergens; D001672:Biocompatible Materials; D003729:Dental Care; D003764:Dental Materials; D006801:Humans; D006967:Hypersensitivity; D012117:Resins, Synthetic
chemical_list: D000485:Allergens; D001672:Biocompatible Materials; D003764:Dental Materials; D012117:Resins, Synthetic