title: Pathogenesis and management of hypertension after kidney transplantation.
abstract: Arterial hypertension is frequently encountered after renal transplantation and is associated not only with increased cardiovascular complications but also with decreased allograft survival. Adequate blood pressure control is, thus, as essential as immunologic surveillance for the long-term transplant care. Nevertheless, randomized control trials assessing treatment targets in these patients are not available and most of the evidence comes from studies in patients with native chronic kidney disease or the general population. In this regard, the renal transplant recipient is treated according to recommendations that are applicable to nontransplanted individuals at high cardiovascular risk. However, the accepted treatment targets for the nontransplanted population are recently being disputed and this makes the management of posttransplant hypertension even more challenging.
authors.affiliation: Division of Nephrology and Hypertension, Department of Medicine, Integrated Research and Treatment Center Transplantation (IFB-Tx) Hannover, Hannover Medical School, Hanover, Germany.
authors.forename: Christos
authors.initials: C
authors.lastname: Chatzikyrkou
authors.forename: Jan
authors.initials: J
authors.lastname: Menne
authors.forename: Wilfried
authors.initials: W
authors.lastname: Gwinner
authors.forename: Bernhard M
authors.initials: BM
authors.lastname: Schmidt
authors.forename: Frank
authors.initials: F
authors.lastname: Lehner
authors.forename: Cornelia
authors.initials: C
authors.lastname: Blume
authors.forename: Anke
authors.initials: A
authors.lastname: Schwarz
authors.forename: Hermann
authors.initials: H
authors.lastname: Haller
authors.forename: Mario
authors.initials: M
authors.lastname: Schiffer
mesh_terms: D000465:Algorithms; D000959:Antihypertensive Agents / Q000627:therapeutic use*; D001794:Blood Pressure / Q000187:drug effects; D006085:Graft Survival; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000209:etiology*; D007165:Immunosuppression Therapy; D007676:Kidney Failure, Chronic / Q000188:drug therapy / Q000503:physiopathology / Q000601:surgery; D016030:Kidney Transplantation / Q000009:adverse effects*; D011183:Postoperative Complications; D016032:Randomized Controlled Trials as Topic; D012084:Renin-Angiotensin System / Q000187:drug effects; D013997:Time Factors
chemical_list: D000959:Antihypertensive Agents