title: [Epilepsy in elderly].
abstract: Seventy-two elderly patients with a possible diagnosis of epilepsy were studied. A study included the evaluation of anamnesis, clinical and neurological examination, EEG and/or video-EEG-monitoring, MRI of the brain. The follow-up period was 1-5 years (on average 3 years). Epilepsy was confirmed in 58 cases. Symptomatic partial epilepsy was diagnosed in 43,1% patients, cryptogenic - in 55,2%. Cerebrovascular accidents were the most frequent cause of symptomatic epilepsy. The distinct feature of the cohort studied was the non-compliance recorded in a half of all patients. In the end of the study, 46,6% patients received carbamazepine, 34,5% - valproate, 24,1% - phenobarbital, 13,8% - topiramate, 3,4% - phenytoin, 1,7% - lamotrigine and 12,1% of patients did not use antiepileptic drugs. Clinical features, efficacy of diagnosis and treatment as well as reasons of non-compliance in elderly epileptic patients were described and analyzed.
authors.forename: A S
authors.initials: AS
authors.lastname: Kotov
authors.forename: I G
authors.initials: IG
authors.lastname: Rudakova
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000375:Aging; D000927:Anticonvulsants / Q000008:administration & dosage*; D002220:Carbamazepine / Q000008:administration & dosage; D004569:Electroencephalography; D004828:Epilepsies, Partial / Q000188:drug therapy* / Q000503:physiopathology*; D004827:Epilepsy / Q000188:drug therapy* / Q000503:physiopathology*; D005260:Female; D005632:Fructose / Q000008:administration & dosage / Q000031:analogs & derivatives; D006801:Humans; D000077213:Lamotrigine; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010349:Patient Compliance; D010634:Phenobarbital / Q000008:administration & dosage; D010672:Phenytoin / Q000008:administration & dosage; D000077236:Topiramate; D014227:Triazines / Q000008:administration & dosage; D014635:Valproic Acid / Q000008:administration & dosage
chemical_list: D000927:Anticonvulsants; D014227:Triazines; D000077236:Topiramate; D005632:Fructose; D002220:Carbamazepine; D014635:Valproic Acid; D010672:Phenytoin; D000077213:Lamotrigine; D010634:Phenobarbital