title: Inhibition of terminal complement activation in severe Shiga toxin-associated HUS - perfect example for a fast track from bench to bedside.
authors.affiliation: Division of Hygiene & Med. Microbiology, Innsbruck Medical University, Innsbruck, Austria.
authors.forename: Dorothea
authors.initials: D
authors.lastname: Orth-Höller
authors.forename: Magdalena
authors.initials: M
authors.lastname: Riedl
authors.forename: Reinhard
authors.initials: R
authors.lastname: Würzner
mesh_terms: D061067:Antibodies, Monoclonal, Humanized / Q000627:therapeutic use*; D003167:Complement Activation / Q000187:drug effects*; D003182:Complement C5 / Q000037:antagonists & inhibitors* / Q000276:immunology; D054324:Enterohemorrhagic Escherichia coli / Q000276:immunology* / Q000502:physiology; D006463:Hemolytic-Uremic Syndrome / Q000188:drug therapy* / Q000276:immunology* / Q000382:microbiology; D006801:Humans; D022621:Shiga Toxin / Q000276:immunology*
chemical_list: D061067:Antibodies, Monoclonal, Humanized; D003182:Complement C5; D022621:Shiga Toxin; C481642:eculizumab