title: Influence of premorbid psychopathology and lesion location on affective and behavioral disorders after ischemic stroke.
abstract: Early recognition of psychopathological symptoms (PSs) after stroke is important because they greatly influence the recovery of patients. The aim of this study was to investigate the predictive factors of PSs occurring in patients with ischemic stroke. Eighty-nine patients were prospectively evaluated upon admission and 4, 12, and 26 weeks later with the Neuropsychiatric Inventory, Hamilton's Rating Scales for Depression and Anxiety, and a battery of neuropsychological and functional scales. Depression and apathy were the most frequent PSs detected after stroke. Premorbid psychopathologies and right-hemisphere location were the main predictive indicators of early and long-term PSs.
authors.affiliation: Department of Neurology, Hospital Virgen del Puerto, Plasencia, Spain. fernando.castellanos@ya.com
authors.forename: Fernando
authors.initials: F
authors.lastname: Castellanos-Pinedo
authors.forename: José María
authors.initials: JM
authors.lastname: Hernández-Pérez
authors.forename: Martín
authors.initials: M
authors.lastname: Zurdo
authors.forename: Beatriz
authors.initials: B
authors.lastname: Rodríguez-Fúnez
authors.forename: José María
authors.initials: JM
authors.lastname: Hernández-Bayo
authors.forename: Ciara
authors.initials: C
authors.lastname: García-Fernández
authors.forename: Bernardo
authors.initials: B
authors.lastname: Cueli-Rincón
authors.forename: Juan Antonio
authors.initials: JA
authors.lastname: Castro-Posada
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001526:Behavioral Symptoms / Q000209:etiology* / Q000473:pathology*; D005260:Female; D006801:Humans; D016014:Linear Models; D008297:Male; D001523:Mental Disorders / Q000209:etiology*; D008875:Middle Aged; D011237:Predictive Value of Tests; D011446:Prospective Studies; D011569:Psychiatric Status Rating Scales; D013223:Statistics as Topic; D020521:Stroke / Q000150:complications*; D013997:Time Factors