title: Whole-genome sequencing informs treatment: personalized medicine takes another step forward.
authors.affiliation: University of Birmingham, Birmingham, UK. k.morrison@bham.ac.uk
authors.forename: Karen E
authors.initials: KE
authors.lastname: Morrison
mesh_terms: D006916:5-Hydroxytryptophan / Q000627:therapeutic use; D000429:Alcohol Oxidoreductases / Q000235:genetics; D002886:Chromosomes, Human, Pair 17 / Q000235:genetics; D020821:Dystonic Disorders / Q000188:drug therapy / Q000235:genetics; D050939:Gene Fusion; D015894:Genome, Human; D006801:Humans; D015473:Leukemia, Promyelocytic, Acute / Q000188:drug therapy / Q000235:genetics; D009154:Mutation; D011110:Polymorphism, Genetic; D057285:Precision Medicine; D018168:Receptors, Retinoic Acid / Q000235:genetics; D000072482:Retinoic Acid Receptor alpha; D017422:Sequence Analysis, DNA; D014178:Translocation, Genetic
chemical_list: C000607071:RARA protein, human; D018168:Receptors, Retinoic Acid; D000072482:Retinoic Acid Receptor alpha; D006916:5-Hydroxytryptophan; D000429:Alcohol Oxidoreductases; C022630:sepiapterin reductase