title: MR imaging-guided cryoablation for the treatment of benign prostatic hyperplasia.
abstract: A patient with benign prostatic hyperplasia presented with chronic lower urinary tract symptoms despite prior surgery and continued medical therapy. Using a magnetic resonance imaging-guided transperineal approach, two cryoprobes were placed into the transition zone of the prostate gland, and two cryoablation freeze-thaw cycles were performed. At 10 weeks after treatment, the frequency of nocturia had decreased from once every 1.5 hours to once per night, urinary peak flow rates had increased from 5.1 mL/s to 10.3 mL/s, and postvoid residual urinary bladder volume had decreased from 187 mL to 58 mL. Improved flow rates and symptoms remained stable 16 weeks after treatment.
authors.affiliation: Department of Radiology, Stanford University Hospital and Clinics, Stanford, California, USA.
authors.forename: Pejman
authors.initials: P
authors.lastname: Ghanouni
authors.forename: Harcharan
authors.initials: H
authors.lastname: Gill
authors.forename: Elena
authors.initials: E
authors.lastname: Kaye
authors.forename: Kim Butts
authors.initials: KB
authors.lastname: Pauly
authors.forename: Bruce
authors.initials: B
authors.lastname: Daniel
mesh_terms: D003452:Cryosurgery; D006801:Humans; D059411:Lower Urinary Tract Symptoms / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology / Q000601:surgery*; D053783:Magnetic Resonance Imaging, Interventional; D008297:Male; D008875:Middle Aged; D053158:Nocturia / Q000209:etiology / Q000503:physiopathology; D011470:Prostatic Hyperplasia / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery*; D013997:Time Factors; D016896:Treatment Outcome; D014563:Urodynamics