title: [Experience in the treatment of interstitial cystitis: review of 17 cases].
abstract: BACKGROUND
  The Interstitial Cystitis (IC) has been considered in the past an uncommon pathology, however it has received a special attention during the last 20 years, (1678 scientific articles published since 1984 to 2009). There are many therapeutic options not at all satisfactory because there isn't consensus about diagnostic and treatment.
  
  
  OBJECTIVE
  To share our experiences in the treatment of interstitial cystitis, additionally, to comment on the therapeutic response of treatment used.
  
  
  METHODS
  Observational, retrospective an analytic study of 17 treated patients from 22 with diagnosis of IC and Bladder Painful Syndrome (IC/BPS) were managed in Urodifem de Occidente, S.C. a private Urogynecologic unit between January 2001 and April 2010. The diagnosis was done in agreement with the concepts of Interstitial Cystitis group from clinical and cystoscopic characteristics. The treatment was: Dimethyl sulfoxide (DIMSO) and Pentosan Polysulfate.
  
  
  RESULTS
  The evaluation was measured by Interstitial Cystitis Symptomatic Index (ICSI) and Interstitial Cystitis Problem Index (ICPI) both validated evaluation instruments, 82% of the patients had a significative improvement of symptomatology and quality of live The ICSI pre and post treatment was of 17.0 and 4.5 and the ICPI was of 14.8 and 4.1 respectively.
  
  
  CONCLUSIONS
  We recommend the use of combine treatment of DIMSO and PPS in cases of I.C.
authors.affiliation: Hospital Civil Fray Antonio Alcalde, CUCS, Universidad de Guadalajara, Jalisco, México. oscar.flores@urodifem.com.mx
authors.forename: Oscar
authors.initials: O
authors.lastname: Flores-Carreras
authors.forename: Claudia J
authors.initials: CJ
authors.lastname: Martínez-Espinoza
authors.forename: María Isabel
authors.initials: MI
authors.lastname: González-Ruiz
mesh_terms: D000283:Administration, Intravesical; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D018856:Cystitis, Interstitial / Q000150:complications / Q000188:drug therapy*; D003907:Dexamethasone / Q000008:administration & dosage / Q000627:therapeutic use; D004121:Dimethyl Sulfoxide / Q000008:administration & dosage / Q000627:therapeutic use*; D004341:Drug Evaluation; D004359:Drug Therapy, Combination; D005260:Female; D006417:Hematuria / Q000188:drug therapy / Q000209:etiology; D006801:Humans; D008875:Middle Aged; D010146:Pain / Q000188:drug therapy / Q000209:etiology; D010426:Pentosan Sulfuric Polyester / Q000008:administration & dosage / Q000627:therapeutic use*; D012189:Retrospective Studies; D016896:Treatment Outcome
chemical_list: D010426:Pentosan Sulfuric Polyester; D003907:Dexamethasone; D004121:Dimethyl Sulfoxide