title: Histamine receptor assays.
abstract: This unit describes three standard in vitro bioassays for studying histamine H₁, H₂ and H₃ receptors in isolated intact tissues removed from the guinea pig. Both the H₁ and H₃ receptor assays are based on preparations of the ileum, whereas the spontaneously beating right atrium assay is used for the H₂-receptor.This unit describes three standard in vitro bioassays for studying histamine H₁, H₂ and H₃ receptors in isolated intact tissue.
authors.affiliation: R.W. Johnson Pharmaceutical Research Institute, La Jolla, California, USA.
authors.forename: N P
authors.initials: NP
authors.lastname: Shankley
authors.forename: M F
authors.initials: MF
authors.lastname: Morton
authors.forename: G F
authors.initials: GF
authors.lastname: Watt
mesh_terms: D000818:Animals; D006168:Guinea Pigs; D017442:Histamine Agonists / Q000378:metabolism; D006633:Histamine Antagonists / Q000378:metabolism; D007082:Ileum / Q000378:metabolism*; D066298:In Vitro Techniques; D008297:Male; D011869:Radioligand Assay / Q000379:methods*; D011968:Receptors, Histamine / Q000378:metabolism*
chemical_list: D017442:Histamine Agonists; D006633:Histamine Antagonists; D011968:Receptors, Histamine