title: [Profile of sex steroids in healthy volunteers' urine during experiment in isolated object].
abstract: The quantitative determination a number of endogenous steroids and their metabolites in urine of healthy volunteers by means of gas chromatography - mass spectrometry was performed. The dynamic of steroid profile of healthy individuals as well as possible ranges of several endogenous steroid parameters have been investigated. Samples were obtained during 105-days experiment with 6 volunteers in isolated on ground modules where were modeling the main life conditions which could influence the steroid profile: meal volume and composition, water consumption, motion activity, air composition and temperature, rate sleep - wakefulness and emotional tension. The parameters of urine steroid profile of healthy volunteer which were affected by life conditions in isolated object were revealed. The parameters of individual and group variability of steroid profile and its dependence from definite experiment conditions - change of salt consumption periods, autonomy of vital activity were detected.
authors.forename: I M
authors.initials: IM
authors.lastname: Larina
authors.forename: E A
authors.initials: EA
authors.lastname: Kochnova
authors.forename: L Kh
authors.initials: LKh
authors.lastname: Pastushkova
authors.forename: G M
authors.initials: GM
authors.lastname: Rodchenkov
authors.forename: A M
authors.initials: AM
authors.lastname: Nosovskiĭ
authors.forename: E N
authors.initials: EN
authors.lastname: Nikolaev
mesh_terms: D000328:Adult; D004644:Emotions; D008401:Gas Chromatography-Mass Spectrometry; D012739:Gonadal Steroid Hormones / Q000652:urine*; D006801:Humans; D008019:Life Style; D008297:Male; D012934:Social Isolation; D014851:Wakefulness
chemical_list: D012739:Gonadal Steroid Hormones