title: Plasmonically active micron-sized beads for integrated solid-phase synthesis and label-free SERS analysis.
abstract: Self-assembly of gold nanospheres with a very thin glass shell onto the surface of beads yields a plasmonically active micron-sized substrate for integrated solid-phase synthesis and label-free SERS analysis. The proof-of-principle of this approach is demonstrated by the vibrational spectroscopic discrimination of three distinct amino acids and a dipeptide.
authors.affiliation: Department of Physics, University of Osnabrück, D-49076 Osnabrück, Germany.
authors.forename: Magdalena
authors.initials: M
authors.lastname: Gellner
authors.forename: Stephan
authors.initials: S
authors.lastname: Niebling
authors.forename: Hannes Y
authors.initials: HY
authors.lastname: Kuchelmeister
authors.forename: Carsten
authors.initials: C
authors.lastname: Schmuck
authors.forename: Sebastian
authors.initials: S
authors.lastname: Schlücker
mesh_terms: D000596:Amino Acids / Q000737:chemistry; D004151:Dipeptides / Q000737:chemistry; D006046:Gold / Q000737:chemistry; D053768:Metal Nanoparticles / Q000737:chemistry; D049329:Nanostructures / Q000737:chemistry*; D010316:Particle Size; D012822:Silicon Dioxide / Q000737:chemistry; D060327:Solid-Phase Synthesis Techniques; D013059:Spectrum Analysis, Raman
chemical_list: D000596:Amino Acids; D004151:Dipeptides; D006046:Gold; D012822:Silicon Dioxide