title: Functional assessment of cancer therapy-brain questionnaire: translation and linguistic adaptation to Brazilian Portuguese.
abstract: OBJECTIVE
  Quality of life assessment among patients with brain tumors is important, given that new treatments have increased patient survival. The aim of this study was to translate the Functional Assessment of Cancer Therapy-Brain (FACT-Br) questionnaire (version 4) into Portuguese, carry out cross-cultural adaptation and assess its reproducibility.
  
  
  METHODS
  Cohort at the Universidade Federal de São Paulo (Unifesp).
  
  
  METHODS
  Forty patients with a brain tumor seen at the neuro-oncology outpatient clinic participated in the study. The process of translation and back-translation was carried out, along with adaptation to the Portuguese language and Brazilian culture. The intraclass correlation coefficient (ICC) was used to test the reproducibility of the FACT-Br (version 4).
  
  
  RESULTS
  The reproducibility of the questionnaire was excellent (ICC = 0.95; 95% confidence interval, CI: 0.89-0.97). The ICC with a mean interval of 15 days between applications of the questionnaire was very good in all domains (ICC = 0.87 to 0.95). The mean time taken to answer the questionnaire was 6.27 ± 2.26 minutes, ranging from 3 to 11 minutes.
  
  
  CONCLUSIONS
  The translated version of the FACT-Br questionnaire (version 4) adapted to the Portuguese language and Brazilian culture proved to be easily understood and achieved very good reproducibility among patients with diagnoses of brain tumors.
authors.affiliation: Neurosurgery Physiotherapy Research Group, Respiratory Division, Universidade Federal de São Paulo, Brazil. marigazzotti@terra.com.br
authors.forename: Mariana Rodrigues
authors.initials: MR
authors.lastname: Gazzotti
authors.forename: Marcela Batan
authors.initials: MB
authors.lastname: Alith
authors.forename: Suzana Maria Fleury
authors.initials: SM
authors.lastname: Malheiros
authors.forename: Milena Carlos
authors.initials: MC
authors.lastname: Vidotto
authors.forename: José Roberto
authors.initials: JR
authors.lastname: Jardim
authors.forename: Oliver Augusto
authors.initials: OA
authors.lastname: Nascimento
mesh_terms: D001932:Brain Neoplasms; D001938:Brazil; D003466:Cultural Characteristics; D005260:Female; D006801:Humans; D007802:Language; D008297:Male; D008875:Middle Aged; D015588:Observer Variation; D011788:Quality of Life; D015203:Reproducibility of Results; D011795:Surveys and Questionnaires / Q000592:standards*; D014177:Translations