title: Survey to determine the seroprevalence of Toxoplasma gondii infection in British sheep flocks.
abstract: A serological survey of Toxoplasma gondii infection in adult breeding sheep in Great Britain was conducted using surplus sera taken during a seroprevalence study of Brucella melitensis in 2009. Of the 3539 sera collected from 227 flocks, 2619 (74 per cent) were found to be positive for T gondii specific antibody when tested using latex agglutination. Multilevel logistic modelling suggested that the likelihood of infection increased with age and this effect appeared to be amplified in animals vaccinated against T gondii. The model also indicated that the odds of sheep being seropositive were increased on premises where cattle were also kept. These results suggest a high level of Toxoplasma infection in breeding sheep in Great Britain and provide further evidence to suggest that postnatal infection is more common than congenital infection in sheep.
authors.affiliation: Animal Health and Veterinary Laboratories Agency (AHVLA) - Newcastle, Whitley Road, NE12 9SE, UK. john.hutchinson@ahvla.gsi.gov.uk
authors.forename: J P
authors.initials: JP
authors.lastname: Hutchinson
authors.forename: A R
authors.initials: AR
authors.lastname: Wear
authors.forename: S L
authors.initials: SL
authors.lastname: Lambton
authors.forename: R P
authors.initials: RP
authors.lastname: Smith
authors.forename: G C
authors.initials: GC
authors.lastname: Pritchard
mesh_terms: D000372:Agglutination Tests / Q000662:veterinary; D000818:Animals; D000913:Antibodies, Protozoan / Q000097:blood*; D005260:Female; D008297:Male; D012307:Risk Factors; D016036:Seroepidemiologic Studies; D012756:Sheep; D012757:Sheep Diseases / Q000453:epidemiology*; D014122:Toxoplasma / Q000276:immunology*; D014124:Toxoplasmosis, Animal / Q000453:epidemiology*; D006113:United Kingdom / Q000453:epidemiology
chemical_list: D000913:Antibodies, Protozoan