title: Acute and long-term safety of external trigeminal nerve stimulation for drug-resistant epilepsy.
abstract: Trigeminal nerve stimulation (TNS) is a novel therapy for drug-resistant epilepsy. We report in detail the safety of external TNS (eTNS), focusing on acute and long-term heart rate and systolic and diastolic blood pressure in response to TNS from the pilot feasibility study. The data indicate that eTNS of the infraorbital and supraorbital branches of the trigeminal nerve is safe and well tolerated.
authors.affiliation: Department of Neurology, Olive View Internal Medicine Program, UCLA School of Medicine, Los Angeles, CA 90095, USA.
authors.forename: Juliana
authors.initials: J
authors.lastname: Pop
authors.forename: Diana
authors.initials: D
authors.lastname: Murray
authors.forename: Daniela
authors.initials: D
authors.lastname: Markovic
authors.forename: Christopher M
authors.initials: CM
authors.lastname: DeGiorgio
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000704:Analysis of Variance; D001794:Blood Pressure / Q000502:physiology; D004599:Electric Stimulation Therapy / Q000379:methods*; D004827:Epilepsy / Q000628:therapy*; D005500:Follow-Up Studies; D006339:Heart Rate / Q000502:physiology; D006801:Humans; D008875:Middle Aged; D013997:Time Factors; D014276:Trigeminal Nerve / Q000502:physiology*; D055815:Young Adult