title: Altered eosinophil proteome in a patient with hypereosinophilia from acute fascioliasis.
abstract: We used comparative proteomics to analyze eosinophils from a patient with hypereosinophilia due to fascioliasis. Using 2-dimensional electrophoresis and mass spectrometry, we demonstrated that the eosinophil proteome was significantly altered compared to those of healthy controls.
authors.affiliation: Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77555-0435, USA.
authors.forename: Christof
authors.initials: C
authors.lastname: Straub
authors.forename: Jason P
authors.initials: JP
authors.lastname: Burnham
authors.forename: A Clinton
authors.initials: AC
authors.lastname: White
authors.forename: Konrad
authors.initials: K
authors.lastname: Pazdrak
authors.forename: Cesar
authors.initials: C
authors.lastname: Sanchez
authors.forename: Luis Carlos
authors.initials: LC
authors.lastname: Watanabe
authors.forename: Alexander
authors.initials: A
authors.lastname: Kurosky
authors.forename: Martín
authors.initials: M
authors.lastname: Montes
mesh_terms: D015180:Electrophoresis, Gel, Two-Dimensional; D004802:Eosinophilia / Q000276:immunology*; D004804:Eosinophils / Q000737:chemistry*; D005211:Fascioliasis / Q000276:immunology*; D005260:Female; D006801:Humans; D013058:Mass Spectrometry; D008875:Middle Aged; D020543:Proteome / Q000032:analysis*
chemical_list: D020543:Proteome