title: A case of acute stent thrombosis during treatment with the thrombopoietin receptor agonist peptide--romiplostim.
abstract: Romiplostim is a thrombopoietin receptor agonist that increases platelet counts and restores platelet function in patients with chronic immune thrombocytopenia (ITP). Increase in platelet count and platelet activation has been associated with increased thromboembolic risk. The present case report describes an interesting case of acute stent thrombosis in a patient with chronic immune thrombocytopenic purpura (ITP) being treated with romiplostim.
authors.affiliation: Department of Cardiology, The Northern Hospital, 185 Cooper Street, Epping, VIC 3076, Australia. rinkumukta@yahoo.com
authors.forename: Rinku
authors.initials: R
authors.lastname: Rayoo
authors.forename: Naveen
authors.initials: N
authors.lastname: Sharma
authors.forename: William J
authors.initials: WJ
authors.lastname: van Gaal
mesh_terms: D000208:Acute Disease; D001241:Aspirin / Q000627:therapeutic use; D002637:Chest Pain; D000077144:Clopidogrel; D000077542:Eptifibatide; D005260:Female; D006801:Humans; D008875:Middle Aged; D010455:Peptides / Q000627:therapeutic use; D010879:Piperazines / Q000627:therapeutic use; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use; D010976:Platelet Count; D000068799:Prasugrel Hydrochloride; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000188:drug therapy*; D053628:Receptors, Thrombopoietin / Q000819:agonists* / Q000096:biosynthesis; D012307:Risk Factors; D015607:Stents; D013876:Thiophenes / Q000627:therapeutic use; D013927:Thrombosis / Q000139:chemically induced*; D013988:Ticlopidine / Q000031:analogs & derivatives / Q000627:therapeutic use; D018084:Ultrasonography, Interventional
chemical_list: D010455:Peptides; D010879:Piperazines; D010975:Platelet Aggregation Inhibitors; D053628:Receptors, Thrombopoietin; D013876:Thiophenes; D000077144:Clopidogrel; D000068799:Prasugrel Hydrochloride; D000077542:Eptifibatide; D013988:Ticlopidine; D001241:Aspirin