title: Herpes zoster infection, vaccination and immunocompromised rheumatology patients.
abstract: Varicella is a self-limiting and relatively mild disease of childhood, although it is frequently more severe and complicated among the immunocompromised rheumatology patients on immunomodulator therapies. In addition, future reactivation of the dormant virus in dorsal root ganglia may cause herpes zoster infection, which can be very debilitating. In this manuscript, we discuss the nature of this infection along with its potential vaccine especially among rheumatology patients.
authors.affiliation: Department of Rheumatology, South Infirmary Victoria University Hospital, Cork, Ireland. mortimeroconnor@gmail.com
authors.forename: Mortimer B
authors.initials: MB
authors.lastname: O'Connor
authors.forename: Mark J
authors.initials: MJ
authors.lastname: Phelan
mesh_terms: D018501:Antirheumatic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D002644:Chickenpox / Q000276:immunology* / Q000517:prevention & control; D019433:Chickenpox Vaccine / Q000009:adverse effects* / Q000276:immunology; D006801:Humans; D016867:Immunocompromised Host / Q000276:immunology*; D007166:Immunosuppressive Agents / Q000009:adverse effects* / Q000627:therapeutic use; D012216:Rheumatic Diseases / Q000188:drug therapy / Q000276:immunology*; D014775:Virus Activation / Q000187:drug effects / Q000276:immunology
chemical_list: D018501:Antirheumatic Agents; D019433:Chickenpox Vaccine; D007166:Immunosuppressive Agents