title: Syntheses and self-assembling behaviors of pentagonal conjugates of tryptophane zipper-forming peptide.
abstract: Pentagonal conjugates of tryptophane zipper-forming peptide (CKTWTWTE) with a pentaazacyclopentadecane core (Pentagonal-Gly-Trpzip and Pentagonal-Ala-Trpzip) were synthesized and their self-assembling behaviors were investigated in water. Pentagonal-Gly-Trpzip self-assembled into nanofibers with the width of about 5 nm in neutral water (pH 7) via formation of tryptophane zipper, which irreversibly converted to nanoribbons by heating. In contrast, Pentagonal-Ala-Trpzip formed irregular aggregates in water.
authors.affiliation: Department of Chemistry and Biochemistry, Graduate School of Engineering, Kyushu University, Moto-oka 744, Nishi-ku, Fukuoka 819-0395, Japan; E-Mails:  ma2ra-k@mail.cstm.kyushu-u.ac.jp  (K.M.);  n-kimi@mail.cstm.kyushu-u.ac.jp  (N.K.).
authors.forename: Kazunori
authors.initials: K
authors.lastname: Matsuura
authors.forename: Kazuya
authors.initials: K
authors.lastname: Murasato
authors.forename: Nobuo
authors.initials: N
authors.lastname: Kimizuka
mesh_terms: D002942:Circular Dichroism; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010455:Peptides / Q000138:chemical synthesis / Q000737:chemistry*; D017510:Protein Folding; D055503:Protein Multimerization; D017433:Protein Structure, Secondary; D014364:Tryptophan / Q000737:chemistry*; D014867:Water / Q000737:chemistry
chemical_list: D010455:Peptides; D014867:Water; D014364:Tryptophan