title: Using conjoint analysis to measure the acceptability of rectal microbicides among men who have sex with men in four South American cities.
abstract: Conjoint Analysis (CJA), a statistical market-based technique that assesses the value consumers place on product characteristics, may be used to predict acceptability of hypothetical products. Rectal Microbicides (RM)-substances that would prevent HIV infection during receptive anal intercourse-will require acceptability data from potential users in multiple settings to inform the development process by providing valuable information on desirable product characteristics and issues surrounding potential barriers to product use. This study applied CJA to explore the acceptability of eight different hypothetical RM among 128 MSM in Lima and Iquitos, Peru; Guayaquil, Ecuador; and Rio de Janeiro, Brazil. Overall RM acceptability was highest in Guayaquil and lowest in Rio. Product effectiveness had the greatest impact on acceptability in all four cities, but the impact of other product characteristics varied by city. This study demonstrates that MSM from the same region but from different cities place different values on RM characteristics that could impact uptake of an actual RM. Understanding specific consumer preferences is crucial during RM product development, clinical trials and eventual product dissemination.
authors.affiliation: Department of Community Health Sciences, School of Public Health, University of California, Los Angeles, USA. jkinsler@yahoo.com
authors.forename: Janni J
authors.initials: JJ
authors.lastname: Kinsler
authors.forename: William E
authors.initials: WE
authors.lastname: Cunningham
authors.forename: César R
authors.initials: CR
authors.lastname: Nureña
authors.forename: Carsten
authors.initials: C
authors.lastname: Nadjat-Haiem
authors.forename: Beatriz
authors.initials: B
authors.lastname: Grinsztejn
authors.forename: Martin
authors.initials: M
authors.lastname: Casapia
authors.forename: Orlando
authors.initials: O
authors.lastname: Montoya-Herrera
authors.forename: Jorge
authors.initials: J
authors.lastname: Sánchez
authors.forename: Jerome T
authors.initials: JT
authors.lastname: Galea
mesh_terms: D000285:Administration, Rectal; D000293:Adolescent; D000328:Adult; D000890:Anti-Infective Agents / Q000008:administration & dosage*; D003256:Community Participation; D015658:HIV Infections / Q000517:prevention & control; D018451:Homosexuality, Male; D006801:Humans; D054327:Lubricants / Q000008:administration & dosage*; D008297:Male; D008389:Marketing of Health Services; D008875:Middle Aged; D015233:Models, Statistical; D010342:Patient Acceptance of Health Care / Q000706:statistics & numerical data*; D012959:Socioeconomic Factors; D013020:South America; D014505:Urban Population; D055815:Young Adult
chemical_list: D000890:Anti-Infective Agents; D054327:Lubricants