title: A zygomycetes-contaminated corneal graft harvested from a donor with signs of orbital trauma.
abstract: OBJECTIVE
  To report the clinical features and histopathology of a transplanted cornea that was immediately replaced because of the possible diagnosis of lattice corneal dystrophy in the graft in which histopathologic examination revealed a Zygomycetes infection.
  
  
  METHODS
  A 19-year-old patient with keratoconus underwent deep anterior lamellar keratoplasty (DALK) in the right eye. The operation was uneventful, transplanting a corneal graft without Descemet membrane, harvested from a donor with signs of orbital trauma.
  
  
  RESULTS
  Three days after keratoplasty, multiple refractile lines involving the entire donor stroma were observed. With the potential diagnosis of lattice dystrophy of the donor cornea, the graft was replaced and sent for histopathologic analysis, which revealed a Zygomycetes graft infection.
  
  
  CONCLUSIONS
  This case report introduces Zygomycetes as a cause of donor-to-host infection and also suggests that corneas harvested from donors with signs of orbital trauma may be a risk factor for donor-to-recipient transmission of such fungal infections.
authors.affiliation: Ophthalmic Research Center and Department of Ophthalmology, Labbafinejad Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran. sepehrfeizi@yahoo.com
authors.forename: Sepehr
authors.initials: S
authors.lastname: Feizi
authors.forename: Mohammad R
authors.initials: MR
authors.lastname: Jafarinasab
authors.forename: Mozhgan R
authors.initials: MR
authors.lastname: Kanavi
mesh_terms: D003316:Corneal Diseases / Q000209:etiology*; D016039:Corneal Transplantation / Q000009:adverse effects*; D018562:Disease Transmission, Infectious; D015821:Eye Infections, Fungal / Q000635:transmission*; D005131:Eye Injuries; D006084:Graft Rejection / Q000209:etiology*; D006801:Humans; D007640:Keratoconus / Q000601:surgery; D008297:Male; D014019:Tissue Donors; D055815:Young Adult; D020096:Zygomycosis / Q000635:transmission*