title: Transistor-like behavior of single metalloprotein junctions.
abstract: Single protein junctions consisting of azurin bridged between a gold substrate and the probe of an electrochemical tunneling microscope (ECSTM) have been obtained by two independent methods that allowed statistical analysis over a large number of measured junctions. Conductance measurements yield (7.3 ± 1.5) × 10(-6)G(0) in agreement with reported estimates using other techniques. Redox gating of the protein with an on/off ratio of 20 was demonstrated and constitutes a proof-of-principle of a single redox protein field-effect transistor.
authors.affiliation: Institute for Bioengineering of Catalonia  (IBEC), Baldiri Reixac 15-21, Barcelona 08028 Spain.
authors.forename: Juan M
authors.initials: JM
authors.lastname: Artés
authors.forename: Ismael
authors.initials: I
authors.lastname: Díez-Pérez
authors.forename: Pau
authors.initials: P
authors.lastname: Gorostiza
mesh_terms: D001400:Azurin / Q000737:chemistry*; D004553:Electric Conductivity; D004566:Electrodes; D004867:Equipment Design; D019544:Equipment Failure Analysis; D006046:Gold / Q000737:chemistry*; D014173:Transistors, Electronic
chemical_list: D001400:Azurin; D006046:Gold