title: Invited commentary.
authors.affiliation: Nationwide Children's Hospital Heart Center, The Ohio State University College of Medicine, Columbus, OH, USA. timothy.hoffman@nationwidechildrens.org
authors.forename: Timothy M
authors.initials: TM
authors.lastname: Hoffman
mesh_terms: D005260:Female; D018729:Fontan Procedure / Q000706:statistics & numerical data*; D006330:Heart Defects, Congenital / Q000401:mortality*; D006801:Humans; D008297:Male; D018570:Risk Assessment / Q000379:methods*