title: Neonatal outcome of macrosomic infants: an analysis of a two-year period.
abstract: OBJECTIVE
  To assess the neonatal outcome of macrosomic neonates in uncomplicated, singleton, term deliveries.
  
  
  METHODS
  A retrospective analysis was performed on 5738 live-born term neonates born in the period 2008-2009. The neonatal outcomes were compared between two birth weight (BW) groups: the macrosomic neonates born with BW≥4000g and a control group: 2500-3999g. There were 410 (7.1%) neonates in the macrosomic group, 4757 (82.9%) in the control group, while 571 (10.0%) were less than 2500g at birth. A correlation analysis of two subgroups of the macrosomic neonates (4000-4499g vs. ≥4500g) was also carried out.
  
  
  RESULTS
  The rate of caesarean section (CS) was significantly higher in the macrosomic group as compared with the control group (49.3% vs. 39.9%), as were the prevalences of hypoglycaemia (6.1% vs. 2.9%), adrenal haemorrhage (0.98% vs. 0.15%) and the male to female ratio (2.15 vs. 0.95). The rate of icterus was significantly higher in the control group (30.4% vs. 18.5%). The macrosomic subgroups were similar in many aspects, but we found significantly more neonates in the higher weight subgroup as regards a low Apgar score, clavicle fracture and the need for intensive care.
  
  
  CONCLUSIONS
  The macrosomic infants were born in good general condition, although those with BW ≥4500g more frequently had an adverse outcome. The macrosomic and control groups' data revealed significant differences in the rate of CS, the male to female ratio, hypoglycaemia and adrenal haemorrhage.
authors.affiliation: Department of Obstetrics and Gynaecology, University of Szeged, Szeged, Hungary. gyurkovits2000@yahoo.com
authors.forename: Zita
authors.initials: Z
authors.lastname: Gyurkovits
authors.forename: Karola
authors.initials: K
authors.lastname: Kálló
authors.forename: Judit
authors.initials: J
authors.lastname: Bakki
authors.forename: Márta
authors.initials: M
authors.lastname: Katona
authors.forename: Tamás
authors.initials: T
authors.lastname: Bitó
authors.forename: Attila
authors.initials: A
authors.lastname: Pál
authors.forename: Hajnalka
authors.initials: H
authors.lastname: Orvos
mesh_terms: D000307:Adrenal Gland Diseases / Q000151:congenital / Q000000981:diagnostic imaging / Q000209:etiology; D001720:Birth Injuries / Q000209:etiology; D001724:Birth Weight; D002585:Cesarean Section; D002968:Clavicle / Q000293:injuries; D016640:Diabetes, Gestational / Q000503:physiopathology; D005260:Female; D005320:Fetal Macrosomia / Q000453:epidemiology / Q000209:etiology* / Q000503:physiopathology*; D050723:Fractures, Bone / Q000151:congenital / Q000209:etiology; D006470:Hemorrhage / Q000151:congenital / Q000000981:diagnostic imaging / Q000209:etiology; D006801:Humans; D006814:Hungary / Q000453:epidemiology; D007003:Hypoglycemia / Q000151:congenital / Q000209:etiology; D015994:Incidence; D007231:Infant, Newborn; D015931:Intensive Care, Neonatal; D007567:Jaundice, Neonatal / Q000209:etiology; D008297:Male; D011247:Pregnancy; D011254:Pregnancy in Diabetics / Q000503:physiopathology; D012189:Retrospective Studies; D017678:Sex Distribution; D014463:Ultrasonography