title: Follicle loss after laparoscopic treatment of ovarian endometriotic cysts.
abstract: OBJECTIVE
  To evaluate follicle loss and its associated factors during laparoscopic cystectomy for ovarian endometrioma.
  
  
  METHODS
  Between October 2008 and December 2009, 140 patients with ovarian cysts undergoing laparoscopic cystectomy at Peking Union Medical Hospital were enrolled: 74 had ovarian endometrioma with no preoperative hormonal therapy (group A), 40 had ovarian endometrioma pretreated with GnRHa (group B), and 26 had non-endometriotic cysts (group C). Pre-, peri- , and postoperative clinical data were collected, and cyst specimens were evaluated histologically.
  
  
  RESULTS
  The number of capsules showing follicles and the mean number of follicles per capsule were lower in group C than in group A or B (P<0.05). Fewer type IIC than type IIB endometriomas showed follicles (P<0.05). The number of follicles per cyst was related negatively to disease duration but positively to pain severity. Women in group A with unilateral endometrioma had a lower mean dysmenorrhea score after the surgery (P<0.05), but no change in basal follicle-stimulating hormone (FSH).
  
  
  CONCLUSIONS
  The type of cyst, disease duration, and severity of dysmenorrhea were associated with ovarian follicle loss during laparoscopic excision of endometrioma. Laparoscopic unilateral cystectomy for endometrioma was effective in relieving pain but had little effect on serum FSH, which might reflect the remaining ovarian reserve.
authors.affiliation: Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China.
authors.forename: Jinghua
authors.initials: J
authors.lastname: Shi
authors.forename: Jinhua
authors.initials: J
authors.lastname: Leng
authors.forename: Quancai
authors.initials: Q
authors.lastname: Cui
authors.forename: Jinghe
authors.initials: J
authors.lastname: Lang
mesh_terms: D000293:Adolescent; D000328:Adult; D002681:China; D004412:Dysmenorrhea / Q000209:etiology; D004715:Endometriosis / Q000601:surgery*; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood; D005500:Follow-Up Studies; D017273:Goserelin / Q000627:therapeutic use; D006801:Humans; D010535:Laparoscopy / Q000009:adverse effects* / Q000379:methods; D008875:Middle Aged; D010048:Ovarian Cysts / Q000601:surgery*; D006080:Ovarian Follicle; D010146:Pain / Q000209:etiology; D012189:Retrospective Studies; D012720:Severity of Illness Index; D013997:Time Factors; D055815:Young Adult
chemical_list: D017273:Goserelin; D005640:Follicle Stimulating Hormone