title: Ulcerated infantile hemangioma treated with imiquimod.
abstract: A 5-month-old boy was observed in our department presenting with an ulcerated infantile hemangioma on the right buttock. This lesion appeared during the first week of life and had been growing progressively, showing ulceration for 3 weeks. We started treatment with corticosteroids, first with the association of betametasone and fusidic acid topically, and then systemically. After 6 weeks of oral treatment as there was no significant improvement, corticosteroid therapy was slowly tapered and local application of imiquimod 5 percent cream, on alternate days, was started. After 12 weeks of therapy with imiquimod there was complete resolution of the ulceration. There were no side effects.
authors.affiliation: Department of Dermatology, Hospital de Santo André, Leiria, Portugal.
authors.forename: Rosa
authors.initials: R
authors.lastname: Mascarenhas
authors.forename: V
authors.initials: V
authors.lastname: Guiote
authors.forename: J
authors.initials: J
authors.lastname: Agro
authors.forename: M
authors.initials: M
authors.lastname: Henrique
mesh_terms: D000634:Aminoquinolines / Q000627:therapeutic use*; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D002081:Buttocks; D006391:Hemangioma / Q000150:complications / Q000188:drug therapy*; D006801:Humans; D000077271:Imiquimod; D007223:Infant; D008297:Male; D012878:Skin Neoplasms / Q000188:drug therapy*; D014456:Ulcer / Q000150:complications
chemical_list: D000634:Aminoquinolines; D000970:Antineoplastic Agents; D000077271:Imiquimod