title: The esophagogastric junction.
abstract: The following discussion of the esophagogastric junctions includes commentaries on the three component structures of the sphincteric segment between the stomach and the esophagus; the pressure contributions from the three sphincteric components in normal subjects and in gastroesophageal reflux (GERD) patients; the mechanism of action of endoscopic plication to determine the underlying pathophysiology of GERD; and in vitro muscle strip studies of defects within the gastroesophageal sphincteric segment potentially leading to GERD.
authors.affiliation: Department of Medicine, Temple University, Philadelphia, Pennsylvania, USA.
authors.forename: Larry S
authors.initials: LS
authors.lastname: Miller
authors.forename: Anil K
authors.initials: AK
authors.lastname: Vegesna
authors.forename: James G
authors.initials: JG
authors.lastname: Brasseur
authors.forename: Alan S
authors.initials: AS
authors.lastname: Braverman
authors.forename: Michael R
authors.initials: MR
authors.lastname: Ruggieri
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D004943:Esophagogastric Junction / Q000473:pathology / Q000502:physiology*; D005764:Gastroesophageal Reflux / Q000473:pathology; D006801:Humans; D066298:In Vitro Techniques; D008875:Middle Aged