title: [Gibberellin signaling pathways in plants].
abstract: During the last decade plant growth and development have been investigated at the molecular level. Plant specific family GRAS-proteins plays one of the key roles in the molecular mechanisms of this process. In this report we highlight the importance of DELLA-proteins and show the model ofgibberellin signalling pathway in plants that starts from the binding of biologically active gibberellic acid with receptor and DELLA-protein. This complex stimulates ubiquitination and degradation of DELLA-proteins through the proteasome pathway. After degradation of DELLA-proteins the repression of plant growth stops that allows gibberellin response to occur. The role of DELLA-proteins as transcription factors is discussed.
authors.forename: G O
authors.initials: GO
authors.lastname: Chebotar
authors.forename: S V
authors.initials: SV
authors.lastname: Chebotar
mesh_terms: D018506:Gene Expression Regulation, Plant; D005875:Gibberellins / Q000235:genetics / Q000378:metabolism*; D063245:Plant Development; D010940:Plant Proteins / Q000235:genetics / Q000378:metabolism*; D010944:Plants / Q000235:genetics / Q000378:metabolism*; D046988:Proteasome Endopeptidase Complex / Q000378:metabolism; D011485:Protein Binding; D011499:Protein Processing, Post-Translational; D018000:Receptors, Peptide / Q000235:genetics / Q000378:metabolism*; D015398:Signal Transduction / Q000502:physiology; D054875:Ubiquitination
chemical_list: D005875:Gibberellins; D010940:Plant Proteins; D018000:Receptors, Peptide; C007842:gibberellic acid; D046988:Proteasome Endopeptidase Complex