title: 19-oxygenated ent-kaurane diterpenoids from Isodon pharicus.
abstract: Eight new 19-oxygenated ENT-kaurane diterpenoids were isolated from the aerial parts of Isodon pharicus. Their structures were determined by means of extensive spectroscopic techniques including interpretation of 1D and 2D NMR spectra. Selected compounds were evaluated for their cytotoxicity against NB4, A549, PC-3, MCF-7, and SH-SY5Y cell lines.
authors.affiliation: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, People's Republic of China.
authors.forename: Yong
authors.initials: Y
authors.lastname: Zhao
authors.forename: Jian-Xin
authors.initials: JX
authors.lastname: Pu
authors.forename: Sheng-Xiong
authors.initials: SX
authors.lastname: Huang
authors.forename: Li-Sheng
authors.initials: LS
authors.lastname: Ding
authors.forename: Li-Mei
authors.initials: LM
authors.lastname: Li
authors.forename: Xian
authors.initials: X
authors.lastname: Li
authors.forename: Li-Bin
authors.initials: LB
authors.lastname: Yang
authors.forename: Wei-Lie
authors.initials: WL
authors.lastname: Xiao
authors.forename: Ying-Li
authors.initials: YL
authors.lastname: Wu
authors.forename: Guo-Qiang
authors.initials: GQ
authors.lastname: Chen
authors.forename: Han-Dong
authors.initials: HD
authors.lastname: Sun
mesh_terms: D045744:Cell Line, Tumor; D004224:Diterpenes / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D006801:Humans; D037602:Isodon / Q000737:chemistry*; D015394:Molecular Structure; D035261:Plant Components, Aerial; D010936:Plant Extracts / Q000737:chemistry* / Q000494:pharmacology
chemical_list: D004224:Diterpenes; D010936:Plant Extracts