title: Carpentier edwards porcine valved conduit for right ventricular outflow tract reconstruction.
abstract: BACKGROUND
  The optimal conduit for right ventricular outflow tract (RVOT) reconstruction is uncertain, with varying degrees of longevity reported for pericardial, homograft, and xenograft valves utilized in this position.
  
  
  METHODS
  A retrospective review of children and adults with congenital heart disease who underwent RVOT reconstruction with the Carpentier Edwards™ (CE) porcine valved conduit was conducted from 2001 to 2009 at the University of Rochester and SUNY Upstate Medical Centers. Clinical data were analyzed for each subject according to conduit size, and all of the Doppler derived transconduit gradients from postoperative echocardiograms were analyzed.
  
  
  RESULTS
  Two hundred and eighteen patients received a single CE conduit for RVOT reconstruction with conduit size ranging from 12 to 30 mm. Perioperative mortality was 1.8% (4/218). Follow-up data were available for 95% of subjects with duration of follow-up ranging from 1 to 9 years. The increase in transconduit gradient over time was inversely proportional to conduit size. For the entire series, freedom from reoperation was 70.3% at 8.2 years. Patients receiving 25 and 30 mm conduits demonstrated no gradient development over this period of follow-up.
  
  
  CONCLUSIONS
  In this series, the CE conduit showed excellent longevity at intermediate term follow-up, with slower progression of conduit stenosis as measured by RVOT gradient change compared with previous reports.
authors.affiliation: Pediatric Cardiac Consortium of Upstate New York, Rochester, New York, USA.
authors.forename: Matthew P
authors.initials: MP
authors.lastname: Schiralli
authors.forename: Jill M
authors.initials: JM
authors.lastname: Cholette
authors.forename: Michael F
authors.initials: MF
authors.lastname: Swartz
authors.forename: Roger
authors.initials: R
authors.lastname: Vermilion
authors.forename: Cecilia
authors.initials: C
authors.lastname: Meagher
authors.forename: George M
authors.initials: GM
authors.lastname: Alfieris
mesh_terms: D000293:Adolescent; D000818:Animals; D001705:Bioprosthesis; D018618:Echocardiography, Doppler, Color; D017548:Echocardiography, Transesophageal; D005260:Female; D005500:Follow-Up Studies; D006350:Heart Valve Prosthesis; D006801:Humans; D008297:Male; D011093:Polyethylene Terephthalates; D011474:Prosthesis Design; D011664:Pulmonary Valve / Q000000981:diagnostic imaging / Q000601:surgery*; D012189:Retrospective Studies; D015607:Stents; D013552:Swine; D016896:Treatment Outcome; D016278:Ventricular Function, Right; D014694:Ventricular Outflow Obstruction / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*
chemical_list: D011093:Polyethylene Terephthalates