title: [The average cell size as a factor reflecting the interaction of the CHO cells during process of proliferation].
abstract: Changes in the cell area during cultivation of the CHO line cells were studied using time-lapse technique (start of registration in one day after cell plating). It was established that the size of the daughter cells after mitosis remains lees than the size of the mother cell for a long time (up to 6 h). Nevertheless, the average cell area of the whole population is constant throughout the observation period (up to 18 h). We assume that this phenomenon could be a result of interaction among dividing and not-dividing cells. The experimental data confirming this conclusion are presented.
authors.forename: Iu P
authors.initials: IuP
authors.lastname: Petrov
authors.forename: Iu A
authors.initials: IuA
authors.lastname: Neguliaev
mesh_terms: D000818:Animals; D016466:CHO Cells; D002450:Cell Communication / Q000502:physiology*; D018929:Cell Culture Techniques; D049108:Cell Enlargement; D049109:Cell Proliferation; D048429:Cell Size; D006224:Cricetinae; D003412:Cricetulus; D007091:Image Processing, Computer-Assisted; D007700:Kinetics; D008853:Microscopy; D013997:Time Factors