title: [Evoked potentials and brainstem reflex activity in patients of young and middle age with chronic headache].
abstract: Neurophysiological peculiarities of functional state of afferent systems, including brain evoked potentials of different modalities and brainstem reflex activity, in patients of young and middle age with chronic headaches have been studied. In young patients, there was the increased reflex activity of visual and trigeminal systems, somatosensory cortex and brainstem structures that indicated the main role of the generator of pathologically increased excitation (GPIE) of different levels in the pathogenesis of chronic pain. In patients of middle age, we observed the predominant role of conduction delay on the supraspinal level. The revealed age-related neurophysiological peculiarities determine the pathogenetic therapy of chronic headaches.
authors.forename: E A
authors.initials: EA
authors.lastname: Kuznetsova
authors.forename: E Z
authors.initials: EZ
authors.lastname: Iakupov
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D001933:Brain Stem / Q000503:physiopathology*; D005071:Evoked Potentials; D005260:Female; D020773:Headache Disorders / Q000503:physiopathology*; D006801:Humans; D008297:Male; D012018:Reflex; D055815:Young Adult