title: Unilateral stellate ganglion block produces bidirectional changes in tissue oxygen tension of the mental nerve in rabbits.
abstract: OBJECTIVE
  The purpose of this study was to investigate changes in the tissue oxygen tension (PO(2)) of the mental nerve bilaterally before and after unilateral stellate ganglion block (SGB).
  
  
  METHODS
  Nine male Japan white rabbits were used. Anesthesia was maintained by a continuous infusion of propofol under mechanical ventilation with room air. For the SGB, the tip of a 26-gauge needle was placed on the left transverse process of the cervical vertebra; 0.2 mL of 1% lidocaine solution was injected. Data were recorded immediately before SGB and when the maximal change in PO(2) after SGB was observed. Observed variables were heart rate, blood pressure, common carotid arterial blood flow, tongue mucosal blood flow, left PO(2), and right PO(2).
  
  
  RESULTS
  PO(2) showed maximal changes 7.9 ± 2.0 minutes after SGB. No changes were observed in heart rate and blood pressure after SGB. Common carotid arterial blood flow, tongue mucosal blood flow, and left PO(2) were increased by 106.4% ± 39.8%, 36.2% ± 35.2%, and 38.7% ± 19.8%, respectively, after SGB. In contrast, right PO(2) was decreased by 29.8% ± 7.4% after SGB.
  
  
  CONCLUSIONS
  These results suggest that unilateral SGB produces bidirectional changes in the PO(2) of the mental nerve and that SGB decreases the PO(2) of the mental nerve on the contralateral side.
authors.affiliation: Department of Dental Anesthesiology, Tokyo Dental College, Chiba, Japan.
authors.forename: Masataka
authors.initials: M
authors.lastname: Kasahara
authors.forename: Yui
authors.initials: Y
authors.lastname: Terakawa
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Ichinohe
authors.forename: Yuzuru
authors.initials: Y
authors.lastname: Kaneko
mesh_terms: D000779:Anesthetics, Local / Q000008:administration & dosage; D000818:Animals; D001794:Blood Pressure / Q000187:drug effects; D017536:Carotid Artery, Common / Q000187:drug effects; D002680:Chin / Q000294:innervation*; D006339:Heart Rate / Q000187:drug effects; D007278:Injections, Spinal / Q000379:methods; D008012:Lidocaine / Q000008:administration & dosage; D008297:Male; D008340:Mandibular Nerve / Q000187:drug effects; D009407:Nerve Block / Q000379:methods*; D010101:Oxygen Consumption / Q000187:drug effects*; D011817:Rabbits; D012039:Regional Blood Flow / Q000187:drug effects; D013233:Stellate Ganglion; D014059:Tongue / Q000098:blood supply
chemical_list: D000779:Anesthetics, Local; D008012:Lidocaine