title: [Influenza H1N1 in obstetric population of a general hospital in Oaxaca].
abstract: BACKGROUND
  In April 2009 are reported the first cases of H1N1 influenza in Mexico, presenting the first death from this cause in the city of Oaxaca in the same month. Different epidemiological reports of pandemics brought to the pregnant and high risk population for complications secondary to infection with influenza H1N1 due to immune status.
  
  
  OBJECTIVE
  describe the obstetric population infected with H1N1 influenza in the Hospital General Dr. Aurelio Valdivieso of Oaxaca.
  
  
  METHODS
  Retrospective and observational study conducted in pregnant women with suspected infection by the virus of the influenza A/H1N1 served in the General Hospital Aurelio Valdivieso of Oaxaca, Oax in 13 patients with influenza H1N1 confirmed by RT-PCR during the pandemic occurred from May 2009 to April 2010.
  
  
  RESULTS
  We reported 27 suspected cases of H1N1 influenza in pregnant women of which 13 were positive by RT-PCR, the cumulative incidence was 1.6 per 1000 pregnant women during the period. The fatality rate was 7.6 per hundred pregnant women affected, one case of maternal death indirectly by fluid and electrolyte imbalance occurred and the attack rate was 0.16 per 100 pregnant women, the main complication of atypical pneumonia occurred in four cases followed by three cases of preeclampsia, infants showed no defects and perinatal outcomes were good to present two cases of admission to the NICU for iatrogenic prematurity without deaths.
  
  
  CONCLUSIONS
  H1N1 influenza infection has a high fatality rate in late pregnancy. Perinatal outcomes did not worsen the condition or management.
authors.affiliation: División de Ginecoobstetricia, Hospital General Dr. Aurelio Valdivieso, Oaxaca. omarcalvoaguilar@hotmail.com
authors.forename: Omar
authors.initials: O
authors.lastname: Calvo Aguilar
authors.forename: Yazmín Ruth
authors.initials: YR
authors.lastname: Canalizo Mendoza
authors.forename: Maritza Jenny
authors.initials: MJ
authors.lastname: Hernández Cuevas
mesh_terms: D000293:Adolescent; D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000998:Antiviral Agents / Q000627:therapeutic use; D003131:Combined Modality Therapy; D005260:Female; D006769:Hospitals, General / Q000706:statistics & numerical data*; D006801:Humans; D007231:Infant, Newborn; D053118:Influenza A Virus, H1N1 Subtype; D007251:Influenza, Human / Q000150:complications / Q000188:drug therapy / Q000453:epidemiology* / Q000821:virology; D008800:Mexico / Q000453:epidemiology; D053139:Oseltamivir / Q000627:therapeutic use; D058873:Pandemics; D011024:Pneumonia, Viral / Q000188:drug therapy / Q000453:epidemiology / Q000209:etiology / Q000628:therapy; D011225:Pre-Eclampsia / Q000453:epidemiology; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000453:epidemiology* / Q000821:virology; D011256:Pregnancy Outcome; D012121:Respiration, Artificial / Q000706:statistics & numerical data; D012189:Retrospective Studies; D014883:Water-Electrolyte Imbalance / Q000209:etiology / Q000401:mortality; D055815:Young Adult
chemical_list: D000900:Anti-Bacterial Agents; D000998:Antiviral Agents; D053139:Oseltamivir