title: Type 2 lepra reaction with HIV1 co-infection: a case report with interesting management implications.
abstract: A patient co-infected with leprosy and Human Immunodeficiency Virus (HIV)-type 1 who developed type 2 lepra reaction in the absence of antiretroviral therapy is presented. The reaction responded only after initiating anti retroviral therapy (ART) despite normal CD4+ counts. The present report suggests that type 2 reactions in leprosy and HIV co-infected patients may not always be the typical manifestation of immune reconstitution inflammatory syndrome (IRIS) and stresses the importance of considering concomitant HIV infection in refractory lepra reactions. Extensive research is required into the manifestations of HIV in leprosy patients.
authors.affiliation: Department of Dematology, Venereology and Leprology, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh-202 002, India. sandeepsemail@rediffmail.com
authors.forename: S
authors.initials: S
authors.lastname: Sachdeva
authors.forename: S S
authors.initials: SS
authors.lastname: Amin
authors.forename: S
authors.initials: S
authors.lastname: Qaisar
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000139:chemically induced* / Q000276:immunology; D000328:Adult; D044966:Anti-Retroviral Agents / Q000627:therapeutic use; D018791:CD4 Lymphocyte Count; D004893:Erythema Nodosum / Q000139:chemically induced* / Q000175:diagnosis; D005260:Female; D015658:HIV Infections / Q000150:complications / Q000188:drug therapy / Q000276:immunology*; D015497:HIV-1; D006801:Humans; D007917:Leprostatic Agents / Q000627:therapeutic use; D015440:Leprosy, Lepromatous / Q000139:chemically induced* / Q000175:diagnosis; D016896:Treatment Outcome
chemical_list: D044966:Anti-Retroviral Agents; D007917:Leprostatic Agents