title: Birth cohort differences in cardiovascular risk factors in a Brazilian population of older elderly: the Bambuí Cohort Study of Aging (1997 and 2008).
abstract: The aim of this study was to investigate whether cohort differences exist in the prevalence of cardiovascular risk factors among older elderly from the Bambuí Cohort Study of Aging. Participants were those aged 71-81 years at two points in time a decade apart: 457 in 1997 (earlier cohort) and 553 in 2008 (recent cohort). The prevalence of hypertension (PR = 1.27; 95%CI: 1.19-1.36) and of diabetes mellitus (PR = 1.39; 95%CI: 1.06-1.83) was higher in the recent cohort compared to the earlier one, regardless of sex. The recent cohort had a lower prevalence of smoking (PR = 0.58; 95%CI: 0.42-0.80), and lower total cholesterol/HDL cholesterol ratio level (PR = 0.85; 95%CI: 0.80-0.89). There was a 136% increase in the pharmacologic treatment of diabetes and a 56% increase in pharmacologic management of hypertension in 2008 in comparison with 1997. Overall, the number of cardiovascular risk factors in the recent cohort remained similar to that of the early cohort.
authors.affiliation: Hospital Universitário de Brasília, Universidade de Brasília, Brasília, Brasil. marcopolo.freitas@gmail.com
authors.forename: Marco Polo Dias
authors.initials: MP
authors.lastname: Freitas
authors.forename: Antônio Ignácio de
authors.initials: AI
authors.lastname: Loyola Filho
authors.forename: Maria Fernanda
authors.initials: MF
authors.lastname: Lima-Costa
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001938:Brazil / Q000453:epidemiology; D002318:Cardiovascular Diseases / Q000453:epidemiology*; D002784:Cholesterol / Q000097:blood; D015331:Cohort Studies; D003920:Diabetes Mellitus / Q000188:drug therapy; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy; D008297:Male; D015995:Prevalence; D012307:Risk Factors; D012907:Smoking / Q000453:epidemiology
chemical_list: D002784:Cholesterol