title: New 1,3-amino alcohols derived from enantiopure bridgehead β-aminobicyclo[2.2.2]oct-5-ene-2-carboxylic acids.
abstract: Constrained enantiopure bicyclic β-amino acids derived from the asymmetric Diels-Alder reaction of the (R)-benzyl-4-(3-acryloyloxy-4,4-dimethyl-2-oxopyrrolidin-1-yl)-benzoate and the 1-(benzyloxycarbonylamino)cyclohexadiene provide original templates for the construction of new rigid enantiopure 1,3-amino alcohols.
authors.affiliation: Institut des Biomolécules Max Mousseron (IBMM) UMR 5247 CNRS-Université Montpellier 1 et 2, Bâtiment Chimie (17), Université Montpellier 2, place E. Bataillon, 34095, Montpellier Cedex 5, France.
authors.forename: Christophe
authors.initials: C
authors.lastname: André
authors.forename: Monique
authors.initials: M
authors.lastname: Calmès
authors.forename: Françoise
authors.initials: F
authors.lastname: Escale
authors.forename: Muriel
authors.initials: M
authors.lastname: Amblard
authors.forename: Jean
authors.initials: J
authors.lastname: Martinez
authors.forename: Olivier
authors.initials: O
authors.lastname: Songis
mesh_terms: D000596:Amino Acids / Q000737:chemistry*; D000605:Amino Alcohols / Q000138:chemical synthesis* / Q000737:chemistry; D001643:Bridged Bicyclo Compounds / Q000737:chemistry*; D002264:Carboxylic Acids / Q000737:chemistry; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D000596:Amino Acids; D000605:Amino Alcohols; D001643:Bridged Bicyclo Compounds; D002264:Carboxylic Acids