title: Multifunctional Giant Amphiphiles via simultaneous copper(I)-catalyzed azide-alkyne cycloaddition and living radical polymerization.
abstract: A novel class of chemically addressable, multifunctional Giant Amphiphiles was synthesized in excellent yields and polydispersity following simultaneous or sequential living radical polymerization and the click, copper(I)-catalysed azide-alkyne cycloaddition (CuAAC). This new approach allows chemical tailoring of the biomacromolecules and in situ formation of nanocontainers.
authors.affiliation: Department of Materials Science and Technology, University of Crete, University Campus Voutes, 71003 Heraklion, Crete, Greece.
authors.forename: Eleftheria
authors.initials: E
authors.lastname: Daskalaki
authors.forename: Benjamin
authors.initials: B
authors.lastname: Le Droumaguet
authors.forename: David
authors.initials: D
authors.lastname: Gérard
authors.forename: Kelly
authors.initials: K
authors.lastname: Velonia
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D000818:Animals; D001386:Azides / Q000737:chemistry*; D002384:Catalysis; D002417:Cattle; D057930:Click Chemistry; D003300:Copper / Q000737:chemistry*; D003500:Cyclization; D057927:Hydrophobic and Hydrophilic Interactions; D008958:Models, Molecular; D015394:Molecular Structure; D011108:Polymers / Q000737:chemistry*; D012710:Serum Albumin, Bovine / Q000737:chemistry*
chemical_list: D000480:Alkynes; D001386:Azides; D011108:Polymers; D012710:Serum Albumin, Bovine; D003300:Copper