title: Effect of AOT-assisted multi-walled carbon nanotubes on antibacterial activity.
abstract: The dispersing power of surfactant-modified multiwalled carbon nanotubes (MWCNTs) and their effect on the antibacterial activity were examined. The MWCNTs were modified using a dioctyl sodium sulfosuccinate (AOT) surfactant. UV-vis spectroscopy and transmission electron microscopy (TEM) were used to characterize the dispersion of MWCNTs in the aqueous phase. Fourier transform infrared spectroscopy confirmed the results of UV-vis spectroscopy and TEM, indicating that the AOT molecules had been adsorbed successfully onto the MWCNT surface. The highly dispersed AOT-modified MWCNTs showed strong antibacterial activity to Streptococcus mutans. The fluorescence images showed that the AOT-modified MWCNTs were capable of capturing bacteria and forming cell aggregates as well as killing them. The optical density growth curves and colony-forming units assays confirmed that the antibacterial activity of the AOT-modified MWCNTs was concentration-dependent and treatment time-dependent. This finding might be useful for applications of AOT-modified MWCNTs as an antibacterial agent to eliminate pathogens from a biocontaminated water phase.
authors.affiliation: Department of Dental Biomaterials, School of Dentistry, Brain Korea 21 Project, Chonbuk National University, Jeonju, South Korea.
authors.forename: Yu
authors.initials: Y
authors.lastname: Bai
authors.forename: Il Song
authors.initials: IS
authors.lastname: Park
authors.forename: Sook Jeong
authors.initials: SJ
authors.lastname: Lee
authors.forename: Pu Shan
authors.initials: PS
authors.lastname: Wen
authors.forename: Tae Sung
authors.initials: TS
authors.lastname: Bae
authors.forename: Min Ho
authors.initials: MH
authors.lastname: Lee
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D008855:Microscopy, Electron, Scanning; D046529:Microscopy, Electron, Transmission; D037742:Nanotubes, Carbon; D013056:Spectrophotometry, Ultraviolet; D017550:Spectroscopy, Fourier Transform Infrared; D013295:Streptococcus mutans / Q000187:drug effects
chemical_list: D000900:Anti-Bacterial Agents; D037742:Nanotubes, Carbon