title: Simultaneous analysis of pesticides from different chemical classes by using a derivatisation step and gas chromatography-mass spectrometry.
abstract: This work presents a new method to analyse simultaneously by GC-MS 31 pesticides from different chemical classes (2,4 D, 2,4 MCPA, alphacypermethrin, bifenthrin, bromoxynil, buprofezin, carbaryl, carbofuran, clopyralid, cyprodinil, deltamethrin dicamba, dichlobenil, dichlorprop, diflufenican, diuron, fenoxaprop, flazasulfuron, fluroxypyr, ioxynil, isoxaben, mecoprop-P, myclobutanil, oryzalin, oxadiazon, picloram, tau-fluvalinate tebuconazole, triclopyr, trifluralin and trinexapac-p-ethyl). This GC-MS method will be applied to the analysis of passive samplers (Tenax(®) tubes and SPME fiber) used for the evaluation of the indoor and outdoor atmospheric contamination by non-agricultural pesticides. The method involves a derivatisation step for thermo-labile or polar pesticides. Different agents were tested and MtBSTFA (N-(t-butyldimethylsilyl)-N-methyltrifluoroacetamide), a sylilation agent producing very specific fragments [M-57], was retained. However, diuron could not be derivatised and the isocyanate product was used for identification and quantification. Pesticides which did not need a derivatisation step were not affected by the presence of the derivatisation agent and they could easily be analysed in mixture with derivatised pesticides. The method can be coupled to a thermal-desorption unit or to SPME extraction for a multiresidue analysis of various pesticides in atmospheric samples.
authors.affiliation: Equipe de Physico-Chimie de l'Atmosphère, LMSPC (UMR 7515 CNRS - Université de Strasbourg), 1, rue Blessig, 67084 Strasbourg Cedex, France.
authors.forename: Caroline
authors.initials: C
authors.lastname: Raeppel
authors.forename: Marie
authors.initials: M
authors.lastname: Nief
authors.forename: Marie
authors.initials: M
authors.lastname: Fabritius
authors.forename: Lucie
authors.initials: L
authors.lastname: Racault
authors.forename: Brice M
authors.initials: BM
authors.lastname: Appenzeller
authors.forename: Maurice
authors.initials: M
authors.lastname: Millet
mesh_terms: D000081:Acetamides; D000215:Acylation; D000577:Amides / Q000737:chemistry; D005463:Fluoroacetates; D005466:Fluorocarbons; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods*; D017646:Organosilicon Compounds / Q000737:chemistry; D010575:Pesticides / Q000032:analysis* / Q000737:chemistry / Q000145:classification; D012680:Sensitivity and Specificity; D014269:Trifluoroacetic Acid / Q000737:chemistry; D014297:Trimethylsilyl Compounds / Q000737:chemistry
chemical_list: D000081:Acetamides; D000577:Amides; D005463:Fluoroacetates; D005466:Fluorocarbons; C103253:N-methyl-bis(heptafluorobutyramide); D017646:Organosilicon Compounds; D010575:Pesticides; D014297:Trimethylsilyl Compounds; C047270:N,N-bis(trimethylsilyl)-2,2,2-trifluoroacetamide; C014666:N-methyl-bis(trifluoroacetamide); C059151:N-methyl-N-(tert-butyldimethylsilyl)trifluoroacetamide; D014269:Trifluoroacetic Acid