title: Global study of viral diarrhea in hospitalized children in Spain: results of structural surveillance of viral gastroenteritis net work (VIGESS-net) 2006-2008.
abstract: OBJECTIVE
  Detection and characterization of gastroenteritis cases (viruses) was conducted during eleven years through the surveillance VIGESS-net, which was created in an effort to conduct a structured surveillance of rotavirus genotypes co-circulating in Spain.
  
  
  RESULTS
  This phase includes the study of 2048 fecal samples from children <5 years old, hospitalized in fifteen different hospitals throughout Spain from March 2006 to March 2008. Of them, 821 (40.1%) samples were rotavirus positive. Rotavirus was identified as the only etiological agent in 694 (33.9%) cases and in 127 (6.2%) was found as coinfection with other enteric viruses, mainly with noroviruses. Predominant G genotypes detected were G1 (49.8%) followed by G9 (32.9%), G3 (2.6%), G8 (1.0%), G4 (0.4%), G6 (0.2%) and G12 (0.2%). The G2 was encountered in 3.2% of cases. Rotavirus mixed G-types infections occurred in 3.9% of cases. The main G/P combinations were G1P[8] (51.9%) and G9P[8] (35.6%), which predominates alternatively in the first and second period of the study. More rare combinations occur in less than 7.4% of cases.
  
  
  CONCLUSIONS
  The diversity of rotavirus circulating strains suggests to maintain a surveillance system through different regions of the country.
authors.affiliation: Viral Gastroenteritis Unit, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Ctra. Majadahonda Km 2, 28220 Madrid, Spain. asanchez@isciii.es
authors.forename: A
authors.initials: A
authors.lastname: Sánchez-Fauquier
authors.forename: V
authors.initials: V
authors.lastname: Montero
authors.forename: J
authors.initials: J
authors.lastname: Colomina
authors.forename: V
authors.initials: V
authors.lastname: González-Galán
authors.forename: J
authors.initials: J
authors.lastname: Aznar
authors.forename: M L
authors.initials: ML
authors.lastname: Aisa
authors.forename: C
authors.initials: C
authors.lastname: Gutierrez
authors.forename: C
authors.initials: C
authors.lastname: Sainz de Baranda
authors.forename: I
authors.initials: I
authors.lastname: Wilhelmi
mesh_terms: D002673:Child, Hospitalized; D002675:Child, Preschool; D060085:Coinfection / Q000453:epidemiology / Q000821:virology; D003967:Diarrhea / Q000453:epidemiology / Q000821:virology; D005243:Feces / Q000821:virology; D005260:Female; D005759:Gastroenteritis / Q000453:epidemiology* / Q000821:virology*; D005838:Genotype; D006801:Humans; D007223:Infant; D008297:Male; D015995:Prevalence; D013030:Spain / Q000453:epidemiology; D014777:Virus Diseases / Q000453:epidemiology* / Q000821:virology*; D014780:Viruses / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*