title: [Pleural puncture biopsy in the aetiological diagnosis of pleurisy].
abstract: BACKGROUND
  Pleurisy represents a worrying situation because of the difficulty of aetiological diagnosis. The aim of this study was to evaluate the contribution of pleural puncture biopsy (PPB) in the diagnosis of pleurisy.
  
  
  METHODS
  A prospective study of the contribution of the pleural puncture biopsy in the pulmonary service of Bamako (Mali) from 2005 to 2009. PPB was used in the investigation of exudative, non-purulent pleurisy of unknown aetiology. Castelin biopsy forceps were used.
  
  
  RESULTS
  Pleurisy was the reason for 20% of the total admissions of 6374 patients. The PPB was performed in 390 patients or 30.6% of the cases of pleurisy. The HIV test was performed in 341 patients (87.4%), of whom 72 cases (21.1%) were positive. The pleural biopsies were: lymphocytic (68.7%), mixed cellular (17.1%). Histological interpretation was possible in 367 biopsy specimens, a yield of 94.1%. Tuberculous granulomata were found in 65.1% with a close relationship to HIV status (P<0.004). Pleural cancer was found in 16.1%.
  
  
  CONCLUSIONS
  The PPB is easy to perform at a low cost. It permits the diagnosis of tuberculous and neoplastic pleurisy, particularly in low income countries with a high prevalence of TB/HIV.
authors.affiliation: Service de pneumophtisiologie, CHU du Point-G, BP 333, Bamako, Mali. toloba71@yahoo.fr
authors.forename: Y
authors.initials: Y
authors.lastname: Toloba
authors.forename: S
authors.initials: S
authors.lastname: Diallo
authors.forename: B-F
authors.initials: BF
authors.lastname: Sissoko
authors.forename: B
authors.initials: B
authors.lastname: Kamaté
authors.forename: K
authors.initials: K
authors.lastname: Ouattara
authors.forename: D
authors.initials: D
authors.lastname: Soumaré
authors.forename: B
authors.initials: B
authors.lastname: Keïta
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001707:Biopsy, Needle / Q000009:adverse effects / Q000191:economics / Q000379:methods; D015897:Comorbidity; D003906:Developing Countries; D019353:Endemic Diseases; D005260:Female; D015658:HIV Infections / Q000453:epidemiology; D006801:Humans; D008214:Lymphocytes / Q000473:pathology; D008297:Male; D008302:Mali / Q000453:epidemiology; D008875:Middle Aged; D010996:Pleural Effusion / Q000175:diagnosis / Q000453:epidemiology / Q000473:pathology; D016066:Pleural Effusion, Malignant / Q000175:diagnosis / Q000453:epidemiology / Q000473:pathology; D010997:Pleural Neoplasms / Q000175:diagnosis / Q000453:epidemiology / Q000473:pathology; D010998:Pleurisy / Q000175:diagnosis* / Q000453:epidemiology / Q000473:pathology; D011030:Pneumothorax / Q000209:etiology; D011446:Prospective Studies; D016037:Single-Blind Method; D014375:Tuberculoma / Q000175:diagnosis / Q000453:epidemiology / Q000473:pathology; D014396:Tuberculosis, Pleural / Q000175:diagnosis* / Q000453:epidemiology / Q000473:pathology; D055815:Young Adult