title: [The chiral mutagens: cytogenetic effects on higher plants].
abstract: The paper covers investigation of cytogenetic activity of chiral mutagens and their specific effects on the plant cells chromosomes of soft winter wheat (Triticum aestivum L.). Comparative analysis of cytogenetic activity of chiral NEU: S(+)1-N-nitroso- 1-N-methyl-3-N-sec-buthylureas (S(+)NMsBU) and R(-)1-N-nitroso- 1N-methyl-3-Nsec-buthylureas (R(-)NMsBU) on winter wheat was performed. As it was shown by the frequency of chromosomal aberrations the S(+) stereoisomer was twice more active than R(-). In addition to typical anaphase aberrations (fragments, bridges, lagging chromosomes) the numerous mitosis pathologies were revealed - K-mitoses, hyperspiralization and despiralization of chromosomes, unequal allocation of chromosomes between the daughter nuclei, mass fragmentation, nondisjunction and chromosome adhesion, three-pole mitoses, etc. Neither of the mentioned pathologies was observed under the action of NEU and gamma-rays.
authors.forename: V V
authors.initials: VV
authors.lastname: Morgun
authors.forename: E A
authors.initials: EA
authors.lastname: Larchenko
authors.forename: R G
authors.initials: RG
authors.lastname: Kostianovskiĭ
authors.forename: A M
authors.initials: AM
authors.lastname: Keterinchuk
mesh_terms: D002467:Cell Nucleus / Q000187:drug effects* / Q000235:genetics / Q000528:radiation effects / Q000648:ultrastructure; D002869:Chromosome Aberrations / Q000187:drug effects* / Q000528:radiation effects; D032461:Chromosomes, Plant / Q000187:drug effects* / Q000528:radiation effects / Q000648:ultrastructure; D005720:Gamma Rays; D008938:Mitosis / Q000187:drug effects* / Q000528:radiation effects; D009153:Mutagens / Q000138:chemical synthesis / Q000494:pharmacology*; D009607:Nitrosourea Compounds / Q000138:chemical synthesis / Q000494:pharmacology*; D013237:Stereoisomerism; D014908:Triticum / Q000166:cytology / Q000187:drug effects / Q000235:genetics / Q000528:radiation effects
chemical_list: D009153:Mutagens; D009607:Nitrosourea Compounds