title: Macrodystrophia lipomatosa involving multiple nerves.
abstract: Macrodystrophia lipomatosa (MDL), a rare congenital disorder, is considered by some to be a localized form of Proteus syndrome. The implication of the PTEN (phosphatase and tensin homolog deleted on chromosome 10) gene in both strengthens this belief. We present a case who had MDL in multiple nerve territories--all on the same side of the body--with hypertrophy of mainly fibroadipose tissue throughout their distribution, thus pointing to a form of localized hemihypertrophy; both hemihypertrophy and lipomatous tumors are components of Proteus syndrome.
authors.affiliation: Department of Radiodiagnosis and Imaging, Postgraduate Institute of Medical Sciences, Pt. B.D. Sharma University of Health Sciences, Rohtak, 124001 Haryana, India.
authors.forename: Seema
authors.initials: S
authors.lastname: Rohilla
authors.forename: Nitin
authors.initials: N
authors.lastname: Jain
authors.forename: Rambaksh
authors.initials: R
authors.lastname: Sharma
authors.forename: Dhara B
authors.initials: DB
authors.lastname: Dhaulakhandi
mesh_terms: D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008069:Lipomatosis, Multiple Symmetrical / Q000175:diagnosis* / Q000601:surgery; D008279:Magnetic Resonance Imaging; D010523:Peripheral Nervous System Diseases / Q000175:diagnosis* / Q000601:surgery; D016715:Proteus Syndrome / Q000175:diagnosis* / Q000601:surgery; D019651:Plastic Surgery Procedures / Q000379:methods*; D055815:Young Adult