title: Prevention of ovarian damage and infertility in young female cancer patients awaiting chemotherapy--clinical approach and unsolved issues.
abstract: Great advances in the oncological therapy of childhood and adolescent cancer patients lead to an increase of young cancer survivors with a normal expectancy of life. The aggressive chemotherapy and/or radiation often compromises endocrine function with consecutive menopausal symptoms and sterility. Recently, new approaches were developed to preserve fertility with different methods to restore the ovarian function. The present review gives an overview of the current possibilities, which may be offered to these young cancer patients, as well as the chances of success and risks and the unsolved issues in special situations.
authors.affiliation: Department of Obstetrics and Gynaecology, University of Ulm, Prittwitzstr 43, 89075 Ulm, Germany. ka_hancke@yahoo.de
authors.forename: Katharina
authors.initials: K
authors.lastname: Hancke
authors.forename: Vladimir
authors.initials: V
authors.lastname: Isachenko
authors.forename: Evgenia
authors.initials: E
authors.lastname: Isachenko
authors.forename: Jürgen M
authors.initials: JM
authors.lastname: Weiss
mesh_terms: D000328:Adult; D005260:Female; D059247:Fertility Preservation; D006801:Humans; D007247:Infertility, Female / Q000139:chemically induced / Q000517:prevention & control*; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000188:drug therapy*; D010053:Ovary / Q000293:injuries*