title: [Peculiarities of urinary bladder cancer tumor cells apoptosis response on neoadjuvant chemotherapy].
abstract: Induced apoptosis in urinary bladder cancer tumor cells of patients was studied using TUNEL reaction. It was shown that increase in induced apoptosis value had a definite correlation between corresponding features of tumor reaction as a response on Gemcitabine-Cisplatin neoadjuvant chemotherapy application. It was found that evaluation of induced apoptosis in urinary bladder cancer tumor cells using TUNEL method allows forecasting the effectiveness of chemotherapy on the cellular level in patients with this type of cancer.
authors.forename: A I
authors.initials: AI
authors.lastname: Iatsyna
authors.forename: É A
authors.initials: ÉA
authors.lastname: Stakhovskiĭ
authors.forename: Ia A
authors.initials: IaA
authors.lastname: Sheremet
authors.forename: S I
authors.initials: SI
authors.lastname: Spivak
authors.forename: A É
authors.initials: AÉ
authors.lastname: Stakhovskiĭ
authors.forename: O N
authors.initials: ON
authors.lastname: Gavriliuk
authors.forename: Iu V
authors.initials: IuV
authors.lastname: Vitruk
authors.forename: A I
authors.initials: AI
authors.lastname: Emets
authors.forename: Ia B
authors.initials: IaB
authors.lastname: Blium
mesh_terms: D000970:Antineoplastic Agents / Q000494:pharmacology* / Q000627:therapeutic use; D017209:Apoptosis / Q000187:drug effects; D015415:Biomarkers / Q000032:analysis; D001706:Biopsy; D002277:Carcinoma / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology; D002454:Cell Differentiation / Q000187:drug effects; D017024:Chemotherapy, Adjuvant / Q000379:methods*; D002945:Cisplatin / Q000494:pharmacology* / Q000627:therapeutic use; D053938:DNA Fragmentation / Q000187:drug effects; D003841:Deoxycytidine / Q000031:analogs & derivatives* / Q000494:pharmacology / Q000627:therapeutic use; D042241:Early Diagnosis; D006801:Humans; D020287:In Situ Nick-End Labeling; D008855:Microscopy, Electron, Scanning; D008856:Microscopy, Fluorescence; D020360:Neoadjuvant Therapy / Q000379:methods*; D009367:Neoplasm Staging; D001749:Urinary Bladder Neoplasms / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology; D000093542:Gemcitabine
chemical_list: D000970:Antineoplastic Agents; D015415:Biomarkers; D003841:Deoxycytidine; D002945:Cisplatin; D000093542:Gemcitabine