title: A new furanocoumarin from the mangrove endophytic fungus Penicillium sp. (ZH16).
abstract: A new furanocoumarin, 5-methyl-8-(3-methylbut-2-enyl) furanocoumarin (1), together with seven known compounds, sterequinone C (2), cyclo(6,7-en-Pro-L-Phe) (3), bergapten, scopoletin, umbelliferone, 1,7-dihydroxyxanthone and 3,5-dimethoxybiphenyl, was isolated from the mangrove endophytic fungus, Penicillium sp. ZH16 obtained from the South China Sea. Their structures were determined by analysis of spectroscopic data. Compound 1 exhibited cytotoxicity against KB and KB(V)200 cells in vitro with IC(50) values 5 and 10 µg mL(-1), respectively.
authors.affiliation: College of Chemistry and Ecology Engineering, Guangxi University for Nationalities, Nanning, Guangxi 530006, China. zhongjinghuang@yahoo.cn
authors.forename: Zhongjing
authors.initials: Z
authors.lastname: Huang
authors.forename: Jianxiang
authors.initials: J
authors.lastname: Yang
authors.forename: Xiaoling
authors.initials: X
authors.lastname: Cai
authors.forename: Zhigang
authors.initials: Z
authors.lastname: She
authors.forename: Yongcheng
authors.initials: Y
authors.lastname: Lin
mesh_terms: D002470:Cell Survival / Q000187:drug effects; D011564:Furocoumarins / Q000737:chemistry* / Q000494:pharmacology; D006367:HeLa Cells; D056945:Hep G2 Cells; D006801:Humans; D010407:Penicillium / Q000737:chemistry*
chemical_list: D011564:Furocoumarins