title: Assessment of the related factors of blood loss and blood ingredients among patients under hypotensive anesthesia in orthognathic surgery.
abstract: OBJECTIVE
  The objective of the study was to understand the factors associated with presurgical and postsurgical blood loss and blood ingredients among patients in the treatment of mandibular prognathism by intraoral vertical ramus osteotomy combined genioplasty.
  
  
  METHODS
  Preoperative and postoperative values of blood loss and blood ingredients were collected from 30 mandibular prognathic patients who underwent orthognathic surgery. The linear regression models and correlation coefficients were used to identify factors with respect to patients' blood loss level and 3 types of blood ingredients (ie, red blood cells, hemoglobin, and hematocrit).
  
  
  RESULTS
  The mean blood loss and operation time were 179.2 mL and 311.7 minutes, respectively. No blood transfusion was received by our patients. After adjusting for potential factors, the regression models showed that no significant factor was found to be associated with blood loss and reduce blood ingredients. Moreover, female patients were found to be more likely to have a low level of presurgical blood ingredients (β = -0.293 to -3.551; P < 0.05), whereas female sex (β = -1.606 to -4.008; P < 0.001), a high blood loss level (β = -0.003 to -0.009; P < 0.05), and long operation time (β = -0.005 to -0.018; P < 0.05) were associated with a low level of postsurgical blood ingredients (ie, hemoglobin and hematocrit).
  
  
  CONCLUSIONS
  No significant factor was associated with blood loss and reduced blood ingredients among patients in orthognathic surgery with hypotenstive anesthesia. Improvements in anesthesia provided surgeons with more time to promote hemostasis during surgery. Hypotensive anesthesia was a well-accepted method to reduce blood loss during orthognathic surgery.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Kaohsiung Medical University, 100 Shih-Chuan 1st Rd, Kaohsiung80708, Taiwan.
authors.forename: Chun-Ming
authors.initials: CM
authors.lastname: Chen
authors.forename: Steven Sheng-Tsung
authors.initials: SS
authors.lastname: Lai
authors.forename: Kun-Jung
authors.initials: KJ
authors.lastname: Hsu
authors.forename: Huey-Er
authors.initials: HE
authors.lastname: Lee
authors.forename: Hsiao-Ling
authors.initials: HL
authors.lastname: Huang
mesh_terms: D000328:Adult; D016063:Blood Loss, Surgical; D004906:Erythrocyte Count; D005260:Female; D006400:Hematocrit; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D007023:Hypotension, Controlled; D016014:Linear Models; D008297:Male; D056948:Orthognathic Surgical Procedures; D011378:Prognathism / Q000601:surgery*; D012189:Retrospective Studies; D012307:Risk Factors
chemical_list: D006454:Hemoglobins