title: Pre-hospital discharge testing after implantable cardioverter defibrillator implantation: a measure of safety or out of date? A retrospective analysis of 975 patients.
abstract: OBJECTIVE
  The present study evaluates the relevance and additional safety value of pre-hospital discharge (PHD) testing in patients with implantable cardioverter defibrillator (ICD) therapy.
  
  
  METHODS
  From June 1998 to May 2009, 975 patients (830 male, 145 female) with ICD were screened retrospectively for failed PHD and analysed for its consequences, risk factors, and patient characteristics after successful intra-operative testing in the implantation procedure.
  
  
  RESULTS
  Pre-hospital discharge testing procedure was performed in 809 cases. No serious adverse events (e.g. death, persistant ventricular fibrillation or ventricular tachycardia, stroke) occurred. The overall incidence of failed PHD was 1.4% (n = 11). The underlying mechanisms were defibrillation threshold failure in 9/11 cases and sensing failure in 2/11 cases.
  
  
  CONCLUSIONS
  In this study predictors for PHD-failure are: (i) cardiomyopathy other than ischaemic or dilative, (ii) young age, and (iii) small or very large left ventricular end-diastolic diameter ( < 40 or > 65 mm). Particularly, (i) manufacture of device or leads, (ii) lead design, (iii) medical treatment, or (iv) gender have no significant influence on PHD failure.
authors.affiliation: Medical Clinic, Department of Internal Medicine and Cardiology,  University of Technology Dresden, Fetscherstr. 76, 01307 Dresden,  Germany.
authors.forename: M
authors.initials: M
authors.lastname: Guenther
authors.forename: T
authors.initials: T
authors.lastname: Rauwolf
authors.forename: B
authors.initials: B
authors.lastname: Brüggemann
authors.forename: M
authors.initials: M
authors.lastname: Gerlach
authors.forename: N K
authors.initials: NK
authors.lastname: Wässnig
authors.forename: M
authors.initials: M
authors.lastname: Christoph
authors.forename: M U
authors.initials: MU
authors.lastname: Braun
authors.forename: R H
authors.initials: RH
authors.lastname: Strasser
authors.forename: C
authors.initials: C
authors.lastname: Wunderlich
mesh_terms: D017677:Age Distribution; D000368:Aged; D001145:Arrhythmias, Cardiac / Q000401:mortality* / Q000517:prevention & control*; D017147:Defibrillators, Implantable / Q000706:statistics & numerical data*; D019544:Equipment Failure Analysis / Q000706:statistics & numerical data*; D004869:Equipment Safety / Q000706:statistics & numerical data; D005260:Female; D005858:Germany / Q000453:epidemiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010351:Patient Discharge / Q000706:statistics & numerical data*; D011475:Prosthesis Failure; D012189:Retrospective Studies; D018570:Risk Assessment; D012307:Risk Factors; D016019:Survival Analysis; D015996:Survival Rate