title: 18F-FDG PET-CT and USG/CT in benign and malignant ovarian tumors with postoperative histopathological correlation.
abstract: OBJECTIVE
  The role of 18F-FDG (18F fluorodeoxyglucose) PET/CT** (Positron emission tomography) in the diagnosis, treatment and follow up of benign and malignant ovarian tumors had been investigated previously. The objective of the following study was to evaluate the predictive value of PET/CT in benign and malignant ovarian tumors and compare with computerized tomography and post-operative pathology.
  
  
  METHODS
  In this retrospective study a total of sixty nine cases with benign or malignant pelvic masses underwent laparotomy at our clinic. Postoperative pathology of the patients was recorded and PET/CT results were compared with ultrasonography computerized tomography and postoperative pathology.
  
  
  RESULTS
  The ROCs and AUCs values four predictors were shown in Figure 1. The AUCs (95 % CI) values calculated for CA 125, ultrasonography (USG), PET/CT and CT were as follows: 0.855 (0.752-0.958), 0.703 (0.540-0.866), 0.681 (0.514-0.848) and 0.631 (0.463-0.799) respectively CA 125 has the highest AUC value in order to predict the malignant potential of the patient. USG has the highest AUC value between the imaging techniques, following PET/CT and CT CONCLUSION: According to this study among four modalities that distinguish malignant potential preoperatively; CA 125 is the best parameter USG and PET provide similar benefits in detecting malignant ovarian masses preoperatively. Both of these parameters are superior to CT Combination of CA 125, USG and PET/CT may be useful in detecting malignant ovarian masses preoperatively resulting in less invasive surgeries.
authors.affiliation: Dicle University, School of Medicine, Department of Obstetrics and Gynecology, Diyarbakir, Turkey.
authors.forename: Umur
authors.initials: U
authors.lastname: Kuyumcuoğlu
authors.forename: Ali Irfan
authors.initials: AI
authors.lastname: Guzel
authors.forename: Yusuf
authors.initials: Y
authors.lastname: Celik
authors.forename: Mahmut
authors.initials: M
authors.lastname: Erdemoğlu
authors.forename: Halil
authors.initials: H
authors.lastname: Komek
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008875:Middle Aged; D009367:Neoplasm Staging; D010049:Ovarian Diseases / Q000175:diagnosis; D010051:Ovarian Neoplasms / Q000175:diagnosis* / Q000473:pathology*; D011044:Poland; D049268:Positron-Emission Tomography / Q000379:methods*; D019275:Radiopharmaceuticals; D015203:Reproducibility of Results; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed / Q000379:methods*; D018615:Ultrasonography, Doppler, Color
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18