title: Porcine xenograft biosynthetic wound dressings for the management of postoperative Mohs wounds.
abstract: Cadaveric allografts and a large variety of other biologic dressings have been reported as being useful for the postoperative management of Mohs micrographic surgery (MMS) wounds. Although the use of porcine xenografts for the immediate postoperative management of these wounds is known, their use has not been detailed in the dermatology literature. A case series of 15 consecutive Mohs micrographic surgery patients (mean age = 74.9 years, range = 49 to 89 years) with wounds initially managed with porcine xenografts is described. Porcine xenografts were useful in a variety of clinical settings following MMS. These included: (1) wound management when tumor margins were indeterminate pending additional dermatopathology studies and (2) wound management when there are issues such as through and through nasal defects involving the mucosa, large wound depth, exposed cartilage and or bone, or patient medical comorbidities that delay or prevent plans for immediate wound reconstruction. Future controlled studies of biologic dressings are needed to determine which options are best for micrographic surgery wounds. Comparisons should also include the traditional option of second intention healing without biologic dressings.
authors.affiliation: The University of Texas Medical Branch, Galveston, Texas, USA.
authors.forename: David W
authors.initials: DW
authors.lastname: Raimer
authors.forename: Ashley R
authors.initials: AR
authors.lastname: Group
authors.forename: Matthew S
authors.initials: MS
authors.lastname: Petitt
authors.forename: Neda
authors.initials: N
authors.lastname: Nosrati
authors.forename: Mika L
authors.initials: ML
authors.lastname: Yamazaki
authors.forename: Nathan A
authors.initials: NA
authors.lastname: Davis
authors.forename: Brent C
authors.initials: BC
authors.lastname: Kelly
authors.forename: Bernard R
authors.initials: BR
authors.lastname: Gibson
authors.forename: Richard D
authors.initials: RD
authors.lastname: Montilla
authors.forename: Richard F
authors.initials: RF
authors.lastname: Wagner
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001672:Biocompatible Materials; D001684:Biological Dressings; D002280:Basal Cell Carcinoma / Q000601:surgery*; D005260:Female; D006801:Humans; D018327:Hutchinson's Melanotic Freckle / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D015580:Mohs Surgery; D011182:Postoperative Care; D012878:Skin Neoplasms / Q000601:surgery*; D014945:Wound Healing
chemical_list: D001672:Biocompatible Materials