title: Synthesis and photophysics of an octathioglycosylated zinc(II) phthalocyanine.
abstract: A water soluble zinc(II) phthalocyanine symmetrically appended with eight thioglucose units was synthesized from commercially available hexadecafluorophthalocyaninatozinc(II) by controlled nucleophilic substitution of the peripheral fluoro groups. The photophysical properties and cancer cell uptake studies of this nonhydrolyzable thioglycosylated phthalocyanine are reported. The new compound has amphiphilic character, is chemically stable, and can potentially be used as a photosensitizer in photodynamic therapy.
authors.affiliation: Department of Chemistry and Biochemistry, Hunter College of the City University of New York, 695 Park Avenue, New York, New York 10065, USA.
authors.forename: Amit
authors.initials: A
authors.lastname: Aggarwal
authors.forename: Sunaina
authors.initials: S
authors.lastname: Singh
authors.forename: Yazhou
authors.initials: Y
authors.lastname: Zhang
authors.forename: Mariah
authors.initials: M
authors.lastname: Anthes
authors.forename: Diana
authors.initials: D
authors.lastname: Samaroo
authors.forename: Ruomei
authors.initials: R
authors.lastname: Gao
authors.forename: Charles Michael
authors.initials: CM
authors.lastname: Drain