title: Increasing αvβ3 selectivity of the anti-angiogenic drug cilengitide by N-methylation.
authors.affiliation: Institute for Advanced Study and Center of Integrated Protein Science, Department Chemie, Technische Universität München, 85747 Garching, Germany.
authors.forename: Carlos
authors.initials: C
authors.lastname: Mas-Moruno
authors.forename: Johannes G
authors.initials: JG
authors.lastname: Beck
authors.forename: Lucas
authors.initials: L
authors.lastname: Doedens
authors.forename: Andreas O
authors.initials: AO
authors.lastname: Frank
authors.forename: Luciana
authors.initials: L
authors.lastname: Marinelli
authors.forename: Sandro
authors.initials: S
authors.lastname: Cosconati
authors.forename: Ettore
authors.initials: E
authors.lastname: Novellino
authors.forename: Horst
authors.initials: H
authors.lastname: Kessler
mesh_terms: D020533:Angiogenesis Inhibitors / Q000737:chemistry* / Q000378:metabolism / Q000494:pharmacology*; D039302:Integrin alphaVbeta3 / Q000737:chemistry / Q000378:metabolism*; D008745:Methylation; D056004:Molecular Dynamics Simulation; D019906:Nuclear Magnetic Resonance, Biomolecular; D019151:Peptide Library; D010456:Peptides, Cyclic / Q000737:chemistry; D011487:Protein Conformation; D019030:Receptors, Vitronectin / Q000737:chemistry; D012910:Snake Venoms / Q000737:chemistry* / Q000378:metabolism* / Q000494:pharmacology*; D013329:Structure-Activity Relationship
chemical_list: D020533:Angiogenesis Inhibitors; D039302:Integrin alphaVbeta3; D019151:Peptide Library; D010456:Peptides, Cyclic; D019030:Receptors, Vitronectin; D012910:Snake Venoms; C064660:integrin alphaVbeta5; C422910:Cilengitide