title: Evolution of genuine cross-correlation strength of focal onset seizures.
abstract: To quantify the evolution of genuine zero-lag cross-correlations of focal onset seizures, we apply a recently introduced multivariate measure to broad band and to narrow-band EEG data. For frequency components below 12.5 Hz, the strength of genuine cross-correlations decreases significantly during the seizure and the immediate postseizure period, while higher frequency bands show a tendency of elevated cross-correlations during the same period. We conclude that in terms of genuine zero-lag cross-correlations, the electrical brain activity as assessed by scalp electrodes shows a significant spatial fragmentation, which might promote seizure offset.
authors.affiliation: Facultad de Ciencias, Universidad Autónoma del Estado de Morelos, Cuernavaca, Mexico. muellerm@buzon.uaem.mx
authors.forename: Markus F
authors.initials: MF
authors.lastname: Müller
authors.forename: Gerold
authors.initials: G
authors.lastname: Baier
authors.forename: Yurytzy López
authors.initials: YL
authors.lastname: Jiménez
authors.forename: Arlex O
authors.initials: AO
authors.lastname: Marín García
authors.forename: Christian
authors.initials: C
authors.lastname: Rummel
authors.forename: Kaspar
authors.initials: K
authors.lastname: Schindler
mesh_terms: D000328:Adult; D058256:Brain Waves; D004569:Electroencephalography; D005260:Female; D006801:Humans; D016014:Linear Models; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D017711:Nonlinear Dynamics; D012189:Retrospective Studies; D012640:Seizures / Q000175:diagnosis* / Q000503:physiopathology; D012815:Signal Processing, Computer-Assisted; D013702:Temporal Lobe / Q000503:physiopathology*; D013997:Time Factors; D055815:Young Adult