title: N-Prolinylanthranilamide pseudopeptides as bifunctional organocatalysts for asymmetric aldol reactions.
abstract: Proline anthranilamide-based pseudopeptides were shown to be effective organocatalysts for enantioselective direct aldol reactions of a selection of aldehydes with various ketones with excellent yield, enantioselectivity up to 99% and anti to syn diastereoselectivity up to 25:1.
authors.affiliation: Department of Chemistry, Case Western Reserve University, Cleveland, Ohio 44106, USA. ajp4@cwru.edu
authors.forename: Anthony J
authors.initials: AJ
authors.lastname: Pearson
authors.forename: Santanu
authors.initials: S
authors.lastname: Panda
mesh_terms: D000447:Aldehydes / Q000737:chemistry*; D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D007659:Ketones / Q000737:chemistry*; D015394:Molecular Structure; D010455:Peptides / Q000737:chemistry; D011392:Proline / Q000031:analogs & derivatives / Q000737:chemistry; D013237:Stereoisomerism; D062367:ortho-Aminobenzoates / Q000737:chemistry*
chemical_list: D000447:Aldehydes; D007659:Ketones; D010455:Peptides; D062367:ortho-Aminobenzoates; D011392:Proline