title: Treatment of a large corneal perforation with a multilayer of amniotic membrane and TachoSil.
abstract: OBJECTIVE
  To describe a novel surgical technique for the sealing of large corneal perforations.
  
  
  METHODS
  Case report of a perforated, 3-mm, postherpetic, corneal ulcer. A single layer of amniotic membrane was sewn to the internal surface of the cornea. An absorbable fibrin sealant patch (TachoSil) was placed in the area of the perforation, and a folded double layer of amniotic membrane was finally sewn to the external face of the cornea.
  
  
  RESULTS
  Surgery without complications, leading to restoration of the anterior chamber and good subjective tolerance.
  
  
  CONCLUSIONS
  The reported technique seems to represent a good alternative emergency procedure for the management of corneal perforations larger than 2 mm.
authors.affiliation: Instituto Clínico Quirúrgico Oftalmológico, Bilbao, Spain.
authors.forename: Arturo E
authors.initials: AE
authors.lastname: Grau
authors.forename: Juan A
authors.initials: JA
authors.lastname: Durán
mesh_terms: D000368:Aged; D000650:Amnion / Q000637:transplantation*; D057112:Corneal Perforation / Q000601:surgery*; D003320:Corneal Ulcer / Q000601:surgery; D004338:Drug Combinations; D015718:Fibrin Tissue Adhesive / Q000627:therapeutic use*; D005340:Fibrinogen / Q000627:therapeutic use*; D006801:Humans; D016849:Keratitis, Herpetic / Q000150:complications; D008297:Male; D013917:Thrombin / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D004338:Drug Combinations; D015718:Fibrin Tissue Adhesive; C518955:TachoSil; D005340:Fibrinogen; D013917:Thrombin