title: [Update of PDE5 inhibitors for the treatment of ischemia-reperfusion].
abstract: Phosphodiesterase type 5 (PDE5) inhibitors are used most commonly in the treatment of penile erectile dysfunction (ED). Recent studies show that PDE5 inhibitors are ideal drugs for treating ischemia-reperfusion injury. This review focuses on the results of basic and clinical researches on PDE5 inhibitors for the treatment of ischemia-reperfusion injury and provides some theoretical evidence for clinical options of the drugs.
authors.affiliation: Department of Urology, The First Hospital Affiliated to Wenzhou Medical College, Wenzhou, Zhejiang 325000, China. huyangyang0577@126.com
authors.forename: Yang-Yang
authors.initials: YY
authors.lastname: Hu
authors.forename: Zhi-Gang
authors.initials: ZG
authors.lastname: Wu
mesh_terms: D007172:Erectile Dysfunction / Q000188:drug therapy*; D006801:Humans; D008297:Male; D058986:Phosphodiesterase 5 Inhibitors / Q000627:therapeutic use*; D010726:Phosphodiesterase Inhibitors / Q000627:therapeutic use*; D015427:Reperfusion Injury / Q000188:drug therapy*
chemical_list: D058986:Phosphodiesterase 5 Inhibitors; D010726:Phosphodiesterase Inhibitors