title: [Ebrictus study. Functional results, survival, and potential years of life lost after the first stroke].
abstract: OBJECTIVE
  To determine the mortality, degree of dependence, survival, and years of life lost (YLL) after first episode of stroke.
  
  
  METHODS
  Cohort study.
  
  
  METHODS
  Community based register.
  
  
  METHODS
  A total of 553 subjects between 15-90 years with a first episode of definitive or transitory stroke were recruited between 01/04/2006 and 31/03/2008.
  
  
  METHODS
  The analyses were performed with the use of time-to-event methods, according to the intention-to-treat principle. The level of dependency was assessed according to the Barthel Scale one year after stroke; YLL (1-70 years) from the mean life expectancies at birth; survival analysis by Kaplan-Meier's curves, bivariate analysis comparing the variables between patients who had survived and those who died, and Cox's multivariate.
  
  
  RESULTS
  The mean age was 73.3 (±11.6 years. The mean time of follow-up was 29.7 ± 13,4 months, during which 26.6% of the patients died. The mean Barthel score fell by >20%, particularly among women. There was moderate or greater dependence in 41.5% (95%CI 30.6-52.8%) of the subjects. The overall accumulative probability of survival was 0.96 (95% CI 0.94-0.97) in the first month and 0.69 (95% CI 0.65-0.72) in the fourth year. The thrombolytic treatment showed a protective effect on mortality, particularly among the women. The main predictive variables were, history of recurrent cardiovascular event (RR 6.7, 95% CI 2.2-21.7) and aging (RR 1.08, 95% CI 1.01-1.2). The average YLL was 11.5/10000/year SD7.2, and higher among men.
  
  
  CONCLUSIONS
  There are differences in functional outcome, mortality, and potential years of life lost by gender. A new cardiovascular event is an independent prognostic factor of survival.
authors.affiliation: Especialista en Medicina de Familia y Comunitaria, Equipo de Atención Primaria Tortosa, Servicio de Atención Primaria Terres de l'Ebre, Institut Català de la Salut, España. jlclua@telefonica.net
authors.forename: J L
authors.initials: JL
authors.lastname: Clua-Espuny
authors.forename: J L
authors.initials: JL
authors.lastname: Piñol-Moreso
authors.forename: A
authors.initials: A
authors.lastname: Panisello-Tafalla
authors.forename: J
authors.initials: J
authors.lastname: Lucas-Noll
authors.forename: V F
authors.initials: VF
authors.lastname: Gil-Guillen
authors.forename: D
authors.initials: D
authors.lastname: Orozco-Beltran
authors.forename: M L
authors.initials: ML
authors.lastname: Queralt-Tomas
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015331:Cohort Studies; D005260:Female; D006801:Humans; D008017:Life Expectancy; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D020521:Stroke / Q000401:mortality* / Q000503:physiopathology*; D015996:Survival Rate; D055815:Young Adult