title: Dehydrative glycosylation with the Hendrickson reagent.
abstract: The Hendrickson reagent is able to perform efficiently dehydrative glycosylation of 1-hydroxyglycosyl donors. The reaction occurs under mild conditions through an anomeric oxophosphonium intermediate detected by nuclear magnetic resonance. Further insight into the mechanism was gained by (18)O labeling of anomeric OH.
authors.affiliation: Dipartimento di Scienze Chimiche, Alimentari, Farmaceutiche e Farmacologiche, Università del Piemonte Orientale, Via Bovio 6, 28100 Novara, Italy.
authors.forename: Matteo
authors.initials: M
authors.lastname: Mossotti
authors.forename: Luigi
authors.initials: L
authors.lastname: Panza
mesh_terms: D006027:Glycosides / Q000737:chemistry*; D006031:Glycosylation; D007202:Indicators and Reagents / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure
chemical_list: D006027:Glycosides; D007202:Indicators and Reagents