title: Successful treatment of psoriasis vulgaris with targeted narrow-band ultraviolet B therapy using a new flat-type fluorescent lamp.
abstract: Narrow-band ultraviolet B (NB-UVB) therapy is widely used for refractory skin diseases. Targeted phototherapy is now being used to reduce the number of sessions and to avoid exposing normal skin. We developed a targeted NB-UVB therapy using a flat-type lamp emitting a wavelength similar to that of the TL-01 fluorescent lamp. Six Japanese patients with psoriasis were recruited and treated with the flat-type NB-UVB device with an initial dose of 70% of the minimal erythema dose, with a 20% increase at each subsequent session. The plaque severity score was determined. All lesions of the tested patients were responsive to NB-UVB therapy using the flat-type lamp. The mean percent reduction of the lesion was 58.3 ± 17.7%. The mean cumulative dose was 20.8 ± 10.8 J/cm². No side effects were observed during treatment. The flat-type targeted NB-UVB device is compact and convenient, and highly effective for the treatment of limited psoriasis lesions.
authors.affiliation: Department of Geriatric and Environmental Dermatology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan. emin@med.nagoya-cu.ac.jp
authors.forename: Emi
authors.initials: E
authors.lastname: Nishida
authors.forename: Takuya
authors.initials: T
authors.lastname: Furuhashi
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Kato
authors.forename: Natsumi
authors.initials: N
authors.lastname: Kaneko
authors.forename: Yoichi
authors.initials: Y
authors.lastname: Shintani
authors.forename: Akimichi
authors.initials: A
authors.lastname: Morita
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011565:Psoriasis / Q000473:pathology / Q000532:radiotherapy*; D014466:Ultraviolet Rays; D014467:Ultraviolet Therapy / Q000295:instrumentation* / Q000379:methods*