title: The missing link: implementation of morphogenetic growth control on the cellular and molecular level.
abstract: In the wing imaginal disc of Drosophila melanogaster, the morphogen Dpp controls growth, probably in an instructive manner. Many models for growth control by Dpp have been proposed and have been extensively discussed elsewhere. In this review, we speculate on how instructive growth control could provide a link between Dpp signaling and cell growth and/or cell cycle progression and so implement morphogenetic growth control on the cellular and molecular levels.
authors.affiliation: Department of Biochemistry and Molecular Biology, Sciences II, 30 Quai Ernest-Ansermet, CH 1211 Geneva 4, Switzerland.
authors.forename: O
authors.initials: O
authors.lastname: Wartlick
authors.forename: M
authors.initials: M
authors.lastname: González-Gaitán
mesh_terms: D000818:Animals; D002453:Cell Cycle; D002455:Cell Division; D049109:Cell Proliferation; D029721:Drosophila Proteins / Q000235:genetics / Q000378:metabolism*; D004331:Drosophila melanogaster / Q000166:cytology / Q000196:embryology* / Q000235:genetics; D018507:Gene Expression Regulation, Developmental; D060227:Imaginal Discs / Q000166:cytology / Q000254:growth & development*; D009024:Morphogenesis / Q000235:genetics*; D015398:Signal Transduction; D014921:Wings, Animal / Q000166:cytology / Q000254:growth & development*
chemical_list: D029721:Drosophila Proteins; C064196:dpp protein, Drosophila