title: A new furanoxanthone from the stem bark of Calophyllum inophyllum.
abstract: The stem bark extracts of Calophyllum inophyllum furnished one new furanoxanthone, inophinnin (1), in addition to inophyllin A (2), macluraxanthone (3), pyranojacareubin (4), 4-hydroxyxanthone, friedelin, stigmasterol, and betulinic acid. The structures of these compounds were determined by spectroscopic analysis of 1D and 2D NMR spectral data ((1)H, (13)C, DEPT, COSY, HMQC, and HMBC) while EI-MS gave the molecular mass. The new xanthone, inophinnin (1), exhibited some anti-inflammatory activity in nitric oxide assay.
authors.affiliation: Department of Chemistry, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia. gwen@science.upm.edu.my
authors.forename: Gwendoline Cheng Lian
authors.initials: GC
authors.lastname: Ee
authors.forename: Siau Hui
authors.initials: SH
authors.lastname: Mah
authors.forename: Mawardi
authors.initials: M
authors.lastname: Rahmani
authors.forename: Yun Hin
authors.initials: YH
authors.lastname: Taufiq-Yap
authors.forename: Soek Sin
authors.initials: SS
authors.lastname: Teh
authors.forename: Yang Mooi
authors.initials: YM
authors.lastname: Lim
mesh_terms: D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D029759:Calophyllum / Q000737:chemistry*; D005663:Furans / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D008296:Malaysia; D051379:Mice; D015394:Molecular Structure; D024301:Plant Bark / Q000737:chemistry; D044004:Xanthones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D005663:Furans; D044004:Xanthones; C568254:inophinnin