title: Α-pyrones and diketopiperazine derivatives from the marine-derived actinomycete Nocardiopsis dassonvillei HR10-5.
abstract: Three new α-pyrones, nocapyrones E-G (1-3), and three new diketopiperazine derivatives, nocazines A-C (4-6), together with a new oxazoline compound, nocazoline A (7), were isolated from the marine-derived actinomycete  Nocardiopsis dassonvillei  HR10-5. The new structures of 1-7 were determined by spectroscopic analysis, X-ray single-crystal diffraction, CD spectra, and modified Mosher and Marfey methods. Compounds 1-3 showed modest antimicrobial activity against  Bacillus subtilis  with MIC values of 26, 14, and 12 μM, respectively.
authors.affiliation: Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, and Affiliated Hospital of Medical College of Qingdao University, Qingdao 266003, People's Republic of China.
authors.forename: Peng
authors.initials: P
authors.lastname: Fu
authors.forename: Peipei
authors.initials: P
authors.lastname: Liu
authors.forename: Haijun
authors.initials: H
authors.lastname: Qu
authors.forename: Yi
authors.initials: Y
authors.lastname: Wang
authors.forename: Dianfeng
authors.initials: D
authors.lastname: Chen
authors.forename: Hui
authors.initials: H
authors.lastname: Wang
authors.forename: Jing
authors.initials: J
authors.lastname: Li
authors.forename: Weiming
authors.initials: W
authors.lastname: Zhu
mesh_terms: D039903:Actinobacteria / Q000737:chemistry*; D000900:Anti-Bacterial Agents / Q000737:chemistry*; D001412:Bacillus subtilis / Q000187:drug effects; D054659:Diketopiperazines / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004354:Drug Screening Assays, Antitumor; D008386:Marine Biology; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D010080:Oxazoles / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D011753:Pyrones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D054659:Diketopiperazines; D010080:Oxazoles; D011753:Pyrones