title: Clinical profiles of Thai patients with ocular myasthenia gravis in Siriraj Hospital.
abstract: Ninety-six patients with ocular myasthenia gravis (OMG) seen at Siriraj Hospital during 1994 to 2004 were retrospectively reviewed. There were 59 female (61.5%) and 37 (38.5%) male patients with mean ages of 39.5 and 33.8 years, respectively Patients presented with initial symptoms of only ptosis in 46.9%, only diplopia in 13.5% and both ptosis and diplopia in 39.6%. However, diplopia alone is uncommon in childhood OMG. Fifteen percent developed systemic symptoms within two years of diagnosis. Thyroid function test was abnormal in 27.5% of investigated patients. Most abnormalities were hyperthyroidism. Thymoma associated with OMG is a rare condition. Most purely OMG patients can control the disease by pyridostigmine, prednisolone or immunosuppressive drugs.
authors.affiliation: Department of Ophthalmology, Faculty of Medicine, Thammasat University, Pathumthani, Thailand.
authors.forename: Supinda
authors.initials: S
authors.lastname: Leeamornsiri
authors.forename: Niphon
authors.initials: N
authors.lastname: Chirapapaisan
authors.forename: Wanicha
authors.initials: W
authors.lastname: Chuenkongkaew
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D017668:Age of Onset; D000368:Aged; D044466:Asian People; D001763:Blepharoptosis / Q000150:complications*; D002648:Child; D002675:Child, Preschool; D003131:Combined Modality Therapy; D004172:Diplopia / Q000150:complications*; D005260:Female; D006784:Hospitals, Teaching; D006801:Humans; D006980:Hyperthyroidism / Q000150:complications* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D009157:Myasthenia Gravis / Q000175:diagnosis* / Q000628:therapy; D015835:Ocular Motility Disorders / Q000175:diagnosis* / Q000628:therapy; D011729:Pyridostigmine Bromide / Q000627:therapeutic use; D012189:Retrospective Studies; D017678:Sex Distribution; D013960:Thyroid Function Tests; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D011729:Pyridostigmine Bromide