title: Organocatalytic asymmetric Michael-type reaction between β,γ-unsaturated α-keto ester and α-nitro ketone.
abstract: A Michael-type reaction of β,γ-unsaturated α-keto ester and α-nitro ketone was established. With a thiourea catalyst derived from cinchona alkaloid, the reactions afford products in 47-94% yields with 68-96% ee.
authors.affiliation: Department of Chemistry, Faculty of Science, Hong Kong Baptist University, Hong Kong, China.
authors.forename: Pengfei
authors.initials: P
authors.lastname: Li
authors.forename: Sau Hing
authors.initials: SH
authors.lastname: Chan
authors.forename: Albert S C
authors.initials: AS
authors.lastname: Chan
authors.forename: Fuk Yee
authors.initials: FY
authors.lastname: Kwong
mesh_terms: D002384:Catalysis; D002930:Cinchona Alkaloids / Q000737:chemistry; D004952:Esters / Q000737:chemistry*; D007659:Ketones / Q000737:chemistry*; D015394:Molecular Structure; D009584:Nitrogen / Q000737:chemistry*; D013237:Stereoisomerism; D013890:Thiourea / Q000737:chemistry
chemical_list: D002930:Cinchona Alkaloids; D004952:Esters; D007659:Ketones; D013890:Thiourea; D009584:Nitrogen