title: [Acute polyradiculoneuropathy in children: the Kairouan pediatric department experience. Report of 22 cases].
abstract: BACKGROUND
  Guillain-Barre Syndrome (GBS) is an acute polyradidulonevritis which is primitive inflammatory and demyelinisant. It represents the most frequent cause of acute peripheric paralysis of the child.
  
  
  OBJECTIVE
  To study the epidemiologic, clinic, electromyographic, outcome and therapeutic features of this disease.
  
  
  METHODS
  22 cases of GBS were reported in the pediatric department of Ibn El Jazzar's hospital of Kairouan from January 1990 to September 2009.
  
  
  RESULTS
  The GBS represents a hospital frequency of 0.45 %o . The mean age of the patients was 6.88 years with a sex ratio of 1.2. The prodromic infectious manifestations were observed in 54.5% of cases. The clinic symptomatology was the muscular deficiency observed in all cases with absence of deep reflex an albumincytologic dissociation was observed in 12 cases. The electromyographic manifestations were: an axonal disorder in four cases, axonomyelinic in eight cases and myelinic in seven cases. A specific therapy by intravenous polyvalent immunoglobulin was prescribed for 14 patients. The evolution was favourable in 10 cases with total recovery three cases of drop foot gait were observed, seven patients were lost to follow up and two patients are dead.
  
  
  CONCLUSIONS
  GB syndrome is the most frequent cause of child acute primitive distal paralysis, since acute polio has been eradicated. Acute Respiratory disorder is the most severe complication this syndrome can lead to in 5% of cases. The course of the disease is often mild and severe scars are only encountered in 5 to 10 % of cases. Indeed, the use intravenous immunoglobulin has utterly changed prognosis.
authors.affiliation: Service de pediatrie, Kairouan.
authors.forename: Fethi
authors.initials: F
authors.lastname: Amri
authors.forename: Zakia
authors.initials: Z
authors.lastname: Habboul
authors.forename: Monia
authors.initials: M
authors.lastname: Troudi
authors.forename: M
authors.initials: M
authors.lastname: Ghribi
authors.forename: Hamdi
authors.initials: H
authors.lastname: Guedhami
authors.forename: Nizar
authors.initials: N
authors.lastname: Khattat
mesh_terms: D002648:Child; D004576:Electromyography; D005260:Female; D020275:Guillain-Barre Syndrome / Q000175:diagnosis* / Q000188:drug therapy* / Q000453:epidemiology; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D008297:Male; D010243:Paralysis / Q000188:drug therapy / Q000209:etiology; D012189:Retrospective Studies; D014416:Tunisia / Q000453:epidemiology
chemical_list: D016756:Immunoglobulins, Intravenous