title: Reference values of tricuspid annular peak systolic velocity in healthy pediatric patients, calculation of z score, and comparison to tricuspid annular plane systolic excursion.
abstract: The tricuspid annular peak systolic velocity (TAPSV) is an echocardiographic measurement assessing right ventricular systolic function in children and adults. We determined the growth-related changes of the TAPSV to establish the references values for the entire pediatric age group. A prospective study was conducted of a group of 860 healthy pediatric patients (age 1 day to 18 years; body surface area [BSA] 0.14 to 2.30 m(2)). We determined the effects of age, gender, and BSA on the TAPSV values. Stepwise linear multiple regression analysis was used to estimate the TAPSV from the age, BSA, and gender. A correlation of normal TAPSV with normal tricuspid annular plane systolic excursion values was performed. The TAPSV ranged from a mean of 7.2 cm/s (z score ± 2: 4.8 to 9.5 cm/s) in the newborn to 14.3 cm/s (z score ± 2: 10.6 to 18.6 cm/s) in the 18-year-old adolescent. The TAPSV values showed a positive correlation with age and BSA, with a nonlinear course. No significant difference was found in the TAPSV values according to gender. A significant correlation was found between the TAPSV and tricuspid annular plane systolic excursion values in our pediatric population. In conclusion, the z scores of the TAPSV values were calculated, and percentile charts were established to serve as reference data for patients with congenital heart disease.
authors.affiliation: Division of Pediatric Cardiology, Department of Pediatrics, Medical University, Graz, Austria. martin.koestenberger@medunigraz.at
authors.forename: Martin
authors.initials: M
authors.lastname: Koestenberger
authors.forename: Bert
authors.initials: B
authors.lastname: Nagel
authors.forename: William
authors.initials: W
authors.lastname: Ravekes
authors.forename: Alexander
authors.initials: A
authors.lastname: Avian
authors.forename: Bernd
authors.initials: B
authors.lastname: Heinzl
authors.forename: Gerhard
authors.initials: G
authors.lastname: Cvirn
authors.forename: Peter
authors.initials: P
authors.lastname: Fritsch
authors.forename: Andrea
authors.initials: A
authors.lastname: Fandl
authors.forename: Thomas
authors.initials: T
authors.lastname: Rehak
authors.forename: Andreas
authors.initials: A
authors.lastname: Gamillscheg
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D015150:Echocardiography, Doppler; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D009200:Myocardial Contraction / Q000502:physiology*; D011446:Prospective Studies; D012016:Reference Values; D013599:Systole; D014261:Tricuspid Valve / Q000000981:diagnostic imaging / Q000502:physiology*; D016278:Ventricular Function, Right / Q000502:physiology*