title: Total hip arthroplasty to treat congenital musculoskeletal abnormalities in the juvenile Down Syndrome hip:  review of literature with case.
abstract: Down Syndrome can result in musculoskeletal abnormalities of the hip at an early age. Avascular necrosis of the femoral head can occur as a result of slipped capital femoral epiphysis causing the patient a great deal of pain, limiting the ability to ambulate. Despite the benefits that this patient group can receive from the surgery, surgeons may be apprehensive to operate. It is our experience that these patients benefit greatly from arthroplasty without complication. In this report, we present a total hip replacement to treat avascular necrosis in an adolescent and address the concerns that surgeons may have in treating this patient population.
authors.affiliation: Division of Orthopaedic Surgery, Mount Sinai Hospital, 600 University Avenue, Toronto, Ontario, Canada. drew.w.taylor@gmail.com
authors.forename: Drew W
authors.initials: DW
authors.lastname: Taylor
authors.forename: Matthew P
authors.initials: MP
authors.lastname: MacDonald
authors.forename: Yona
authors.initials: Y
authors.lastname: Kosashvili
authors.forename: Allan E
authors.initials: AE
authors.lastname: Gross
mesh_terms: D000203:Activities of Daily Living; D000293:Adolescent; D019644:Arthroplasty, Replacement, Hip / Q000379:methods*; D004314:Down Syndrome / Q000150:complications / Q000473:pathology / Q000601:surgery*; D005271:Femur Head Necrosis / Q000209:etiology / Q000473:pathology / Q000601:surgery*; D006617:Hip Dislocation / Q000209:etiology / Q000601:surgery*; D006801:Humans; D008297:Male; D010027:Osteotomy / Q000009:adverse effects*; D011183:Postoperative Complications / Q000601:surgery*; D011788:Quality of Life; D020127:Recovery of Function; D060048:Slipped Capital Femoral Epiphyses / Q000209:etiology / Q000473:pathology / Q000601:surgery; D017211:Treatment Failure; D016896:Treatment Outcome