title: Towards a reliable technology for antioxidant capacity and oxidative damage evaluation: electrochemical (bio)sensors.
abstract: To counteract and prevent the deleterious effect of free radicals the living organisms have developed complex endogenous and exogenous antioxidant systems. Several analytical methodologies have been proposed in order to quantify antioxidants in food, beverages and biological fluids. This paper revises the electroanalytical approaches developed for the assessment of the total or individual antioxidant capacity. Four electrochemical sensing approaches have been identified, based on the direct electrochemical detection of antioxidant at bare or chemically modified electrodes, and using enzymatic and DNA-based biosensors.
authors.affiliation: REQUIMTE/Instituto Superior de Engenharia do Porto, Porto, Portugal. mfb@isep.ipp.pt
authors.forename: M Fátima
authors.initials: MF
authors.lastname: Barroso
authors.forename: N
authors.initials: N
authors.lastname: de-los-Santos-Álvarez
authors.forename: C
authors.initials: C
authors.lastname: Delerue-Matos
authors.forename: M B P P
authors.initials: MB
authors.lastname: Oliveira
mesh_terms: D000975:Antioxidants / Q000032:analysis*; D015374:Biosensing Techniques / Q000295:instrumentation*; D017076:Computer-Aided Design; D003217:Conductometry / Q000295:instrumentation*; D004867:Equipment Design; D019544:Equipment Failure Analysis; D005504:Food Analysis / Q000295:instrumentation*; D020411:Oligonucleotide Array Sequence Analysis / Q000295:instrumentation*; D018384:Oxidative Stress
chemical_list: D000975:Antioxidants