title: 3' processing in protists.
abstract: Molecular biologists have traditionally focused on the very small corner of eukaryotic evolution that includes yeast and animals; even plants have been neglected. In this article, we describe the scant information that is available concerning RNA processing in the other four major eukaryotic groups, especially pathogenic protists. We focus mainly on polyadenylation and nuclear processing of stable RNAs. These processes have--where examined--been shown to be conserved, but there are many novel details. We also briefly mention other processing reactions such as splicing.
authors.affiliation: Zentrum für Molekulare Biologie der Universität Heidelberg, DKFZ-ZMBH Alliance, Im Neuenheimer Feld 282, Heidelberg, Germany. cclayton@zmbh.uni-heidelberg.de
authors.forename: Christine
authors.initials: C
authors.lastname: Clayton
authors.forename: Shula
authors.initials: S
authors.lastname: Michaeli
mesh_terms: D056893:Alveolata / Q000235:genetics / Q000378:metabolism; D056894:Amoebozoa / Q000235:genetics / Q000378:metabolism; D000818:Animals; D016828:Diplomonadida / Q000235:genetics / Q000378:metabolism; D056898:Euglenozoa / Q000235:genetics / Q000378:metabolism; D056890:Eukaryota / Q000235:genetics* / Q000378:metabolism*; D006801:Humans; D056900:Parabasalidea / Q000235:genetics / Q000378:metabolism; D010802:Phylogeny; D026721:RNA 3' End Processing / Q000235:genetics / Q000502:physiology*; D016337:RNA, Catalytic / Q000235:genetics / Q000378:metabolism; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism
chemical_list: D016337:RNA, Catalytic; D012333:RNA, Messenger