title: Mortality study in an asbestos cement factory in Naples, Italy.
abstract: The objective of this paper is to investigate mortality among 1247 male asbestos-cement workers employed in an asbestos-cement plant located in Naples. The cohort included 1247 men hired between 1950 and 1986. The follow-up began on January 1st 1965. The vital status and causes of death were ascertained up to December 31 2005. Cause-specific mortality rates of the Campania Region population were used as reference. Relative risks were estimated using Standardized Mortality Ratios (SMRs), and the confidence intervals were calculated at a 95% level (95% CI). A significant increase in mortality was observed for respiratory disease (81 deaths; SMR = 187; 95% CI = 149- 233), particularly for pneumoconiosis (42 deaths; SMR = 13 313; 95% CI = 9595-17 996) of which 41 deaths for asbestosis (SMR = 43 385; 95% CI = 31 134-58 857), for pleural cancer (24 deaths; SMR = 2617; 95% CI = 1677-3893), for lung cancer (84 deaths; SMR=153; 95% CI = 122-189) and for peritoneal cancer (9 deaths; SMR = 1985; 95% CI = 908-3769). Non-significant increases were also observed for rectum cancer (6 deaths; SMR = 157; 95% CI = 58-342). In conclusion, consistently with other mortality studies on asbestos-cement workers performed in different countries, an increased mortality from asbestosis, lung cancer, pleural and peritoneal mesothelioma was detected in the present cohort.
authors.affiliation: Registro Mesoteliomi della Campania, Centro Operativo Regionale del Registro Nazionale dei casi di neoplasia di sospetta origine professionale, Dipartimento di Medicina Sperimentale, Seconda Università degli Studi di Napoli, Naples, Italy. simonamenegozzo@libero.it
authors.forename: Simona
authors.initials: S
authors.lastname: Menegozzo
authors.forename: Pietro
authors.initials: P
authors.lastname: Comba
authors.forename: Daniela
authors.initials: D
authors.lastname: Ferrante
authors.forename: Marco
authors.initials: M
authors.lastname: De Santis
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Gorini
authors.forename: Francesco
authors.initials: F
authors.lastname: Izzo
authors.forename: Corrado
authors.initials: C
authors.lastname: Magnani
authors.forename: Roberta
authors.initials: R
authors.lastname: Pirastu
authors.forename: Andrea
authors.initials: A
authors.lastname: Simonetti
authors.forename: Sara
authors.initials: S
authors.lastname: Tùnesi
authors.forename: Massimo
authors.initials: M
authors.lastname: Menegozzo
mesh_terms: D000328:Adult; D000368:Aged; D001194:Asbestos; D001195:Asbestosis / Q000401:mortality*; D002273:Carcinogens; D002318:Cardiovascular Diseases / Q000139:chemically induced / Q000401:mortality; D015331:Cohort Studies; D003252:Construction Materials; D005260:Female; D006801:Humans; D007558:Italy / Q000453:epidemiology; D008175:Lung Neoplasms / Q000453:epidemiology / Q000401:mortality; D008297:Male; D008654:Mesothelioma / Q000453:epidemiology / Q000401:mortality; D008875:Middle Aged; D009784:Occupational Diseases / Q000139:chemically induced / Q000453:epidemiology* / Q000401:mortality*; D016273:Occupational Exposure / Q000032:analysis; D010534:Peritoneal Neoplasms / Q000453:epidemiology / Q000401:mortality; D010997:Pleural Neoplasms / Q000453:epidemiology / Q000401:mortality; D011009:Pneumoconiosis / Q000401:mortality; D011153:Population; D012042:Registries; D055815:Young Adult
chemical_list: D002273:Carcinogens; D001194:Asbestos