title: Preparation of high purity biphenyl cyclooctene lignans from Schisandra extract by ion exchange resin catalytic transformation combined with macroporous resin separation.
abstract: In this study, ester-bond biphenyl cyclooctene lignans were efficiently hydrolytically degraded into free biphenyl cyclooctene lignans by ion exchange resin transformation and simultaneous removal of impurities by macroporous resin. The OH-type strongly basic anion exchange resin 201×7 was the best one, and the dynamic hydrolysis efficiency was 146.7±5.0%. HPD5000 macroporous resin, which offered higher adsorption and desorption capacities and faster adsorption than other resins. The purity of free biphenyl cyclooctene lignans in the product increased from 5.14±0.24% to 79.67±0.0.67%. After dynamic catalytic transformation by 201×7 resin combined with purification of HPD5000 resin, the yield and the purity of free biphenyl cyclooctene lignans in the product were 132.1±4.7% and 80.91±3.53%, respectively.
authors.affiliation: Key Laboratory of Forest Plant Ecology, Ministry of Education, Northeast Forestry University, Harbin, China.
authors.forename: Chun-hui
authors.initials: CH
authors.lastname: Ma
authors.forename: Ting-ting
authors.initials: TT
authors.lastname: Liu
authors.forename: Lei
authors.initials: L
authors.lastname: Yang
authors.forename: Yuan-gang
authors.initials: YG
authors.lastname: Zu
authors.forename: Feng-jian
authors.initials: FJ
authors.lastname: Yang
authors.forename: Chun-jian
authors.initials: CJ
authors.lastname: Zhao
authors.forename: Lin
authors.initials: L
authors.lastname: Zhang
authors.forename: Zhong-hua
authors.initials: ZH
authors.lastname: Zhang
mesh_terms: D000327:Adsorption; D000704:Analysis of Variance; D002852:Chromatography, Ion Exchange / Q000379:methods*; D034242:Cyclooctanes / Q000302:isolation & purification*; D004149:Dioxoles / Q000302:isolation & purification*; D000431:Ethanol; D005638:Fruit / Q000737:chemistry; D006868:Hydrolysis; D007475:Ion Exchange Resins; D017705:Lignans / Q000302:isolation & purification*; D010936:Plant Extracts / Q000737:chemistry; D011083:Polycyclic Compounds / Q000302:isolation & purification*; D032141:Schisandra / Q000737:chemistry*; D021241:Spectrometry, Mass, Electrospray Ionization; D013696:Temperature
chemical_list: D034242:Cyclooctanes; D004149:Dioxoles; D007475:Ion Exchange Resins; D017705:Lignans; D010936:Plant Extracts; D011083:Polycyclic Compounds; D000431:Ethanol; C034734:schizandrin A; C034557:schizandrer A; C011105:schizandrin