title: The use of anti-osteoporosis drugs in total knee arthroplasty.
abstract: Stress shielding, osteolysis, lack of integration affect the clinical results of total joint arthroplasty. Drugs as bisphosphonates administered after surgery may improve the fixation of the components to the bone, preserving the survival of the implant: however, few reports regarding applications in Total Knee Arthroplasty (TKA) are published.
authors.affiliation: First Orthopaedic Clinic, Orthopaedic Traumatologic Center, University of Florence, Italy. christian.carulli@unifi.it
authors.forename: Christian
authors.initials: C
authors.lastname: Carulli
authors.forename: Roberto
authors.initials: R
authors.lastname: Civinini
authors.forename: Fabrizio
authors.initials: F
authors.lastname: Matassi
authors.forename: Marco
authors.initials: M
authors.lastname: Villano
authors.forename: Massimo
authors.initials: M
authors.lastname: Innocenti
mesh_terms: D019645:Arthroplasty, Replacement, Knee / Q000379:methods*; D050071:Bone Density Conservation Agents / Q000494:pharmacology*; D016723:Bone Remodeling; D001842:Bone and Bones; D004164:Diphosphonates; D006801:Humans; D007719:Knee Joint / Q000601:surgery; D007720:Knee Prosthesis; D010024:Osteoporosis / Q000188:drug therapy*; D011474:Prosthesis Design
chemical_list: D050071:Bone Density Conservation Agents; D004164:Diphosphonates