title: Short and efficient synthetic route to methyl α-trioxacarcinoside B and anomerically activated derivatives.
abstract: A 9-step synthetic route to the complex carbohydrate methyl α-trioxacarcinoside B from 2-acetylfuran is described. Anomerically activated forms, including 1-phenylthio, 1-O-(4'-pentenyl), 1-fluoro, and 1-O-acetyl derivatives are also prepared.
authors.affiliation: Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts 02138, USA.
authors.forename: Thomas
authors.initials: T
authors.lastname: Magauer
authors.forename: Andrew G
authors.initials: AG
authors.lastname: Myers
mesh_terms: D005663:Furans / Q000737:chemistry*; D015394:Molecular Structure; D009005:Monosaccharides / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D005663:Furans; D009005:Monosaccharides; C568586:methyl alpha-trioxacarcinoside B; C039669:2-acetylfuran