title: A novel lignan glycoside with antioxidant activity from Tinospora sagittata var. yunnanensis.
abstract: A novel lignan glysocide, namely sagitiside A (1), together with two known ones, (+)-lyoniresinol-2α-O-β-D-glucopyranoside (2) and (+)-5'-methoxyisolariciresinol 3α-O-β-D-glucopyranoside (3), was isolated from the 95% ethanol extract of dry roots of Tinospora sagittata var. yunnanensis. The structure of the new compound (1) was determined based on MS, 1D and 2D NMR spectral data. Compounds 1-3 showed antioxidant activity with EC(50) values 55, 75 and 80 µM by 1,1-diphenyl-2-picryhydrazyl (DPPH) radical-scavenging assay.
authors.affiliation: Key Laboratory of Ethnic Medicine Resource Chemistry, State Ethnic Affairs Commission and Ministry of Education, School of Chemistry and Biotechnology, Yunnan University of Nationalities, Kunming 650031, China.
authors.forename: Xiang-Zhong
authors.initials: XZ
authors.lastname: Huang
authors.forename: Chun-Mei
authors.initials: CM
authors.lastname: Cheng
authors.forename: Yun
authors.initials: Y
authors.lastname: Dai
authors.forename: Guang-Miao
authors.initials: GM
authors.lastname: Fu
authors.forename: Jun-Ming
authors.initials: JM
authors.lastname: Guo
authors.forename: Hui
authors.initials: H
authors.lastname: Liang
authors.forename: Chao
authors.initials: C
authors.lastname: Wang
mesh_terms: D000975:Antioxidants / Q000737:chemistry*; D006027:Glycosides / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D018517:Plant Roots / Q000737:chemistry*; D031610:Tinospora / Q000737:chemistry*
chemical_list: D000975:Antioxidants; D006027:Glycosides