title: [Aging eyelid: clinical, morphological manifestations and peculiarities of microcirculation].
abstract: Morphological study of eyelid biopsy tissues with varying degrees of age-related changes revealed sclerosis, infiltration, expansion and the convoluted configuration of the walls of blood vessels, stasis, reflecting microcirculation disturbance in the skin. Decrease in elasticity, elasticity and skin turgor in aging eyelids is largely due to the thinning, randomly distributed bundles of collagen and a decrease in the number or total absence of elastic fibers. In 31 patients with blepharohalasis laser Doppler flowmetry revealed a failure in the neuromuscular regulation of vascular tone, which is a manifestation of chronic stagnation in the microcirculatory bed. Revealed changes in the morphological structure of eyelid skin and microcirculatory bed confirm the trophic disturbances and congestion occurring in the skin of eyelids with aging.
authors.forename: S V
authors.initials: SV
authors.lastname: Grishchenko
authors.forename: E N
authors.initials: EN
authors.lastname: Borkhunova
authors.forename: I A
authors.initials: IA
authors.lastname: Filatova
authors.forename: I V
authors.initials: IV
authors.lastname: Vissarionova
mesh_terms: D000328:Adult; D000368:Aged; D005143:Eyelids / Q000098:blood supply* / Q000473:pathology*; D005260:Female; D006801:Humans; D017078:Laser-Doppler Flowmetry; D008297:Male; D008833:Microcirculation; D008875:Middle Aged; D012039:Regional Blood Flow; D015595:Skin Aging / Q000473:pathology*