title: A 27-year-old woman diagnosed as polycystic ovary syndrome associated with Graves' disease.
abstract: Polycystic ovary syndrome (PCOS) and Graves' disease are the common causes of menstrual irregularity leading to infertility in women of child-bearing age. A 21-year-old female patient visited us with complaints of oligomenorrhea and hand tremor. She was diagnosed as having PCOS and hyperthyroid Graves' disease, simultaneously. She had low body weight (BMI: 16.4 kg/m(2)), mild hirsutism, and thyrotoxicosis. The patient was treated with anti-thyroid drug and beta-blocker for about two years, and then recovered to normal thyroid function. Although some studies have suggested a connection between PCOS and autoimmune thyroiditis, no study indicated that PCOS is associated with Graves' disease until now. Here, we describe the first case report of a lean woman with normal insulin sensitivity presenting PCOS and Graves' disease simultaneously.
authors.affiliation: Department of Internal Medicine, Gyeongsang National University School of Medicine, South Korea.
authors.forename: Jung Hwa
authors.initials: JH
authors.lastname: Jung
authors.forename: Jong Ryeal
authors.initials: JR
authors.lastname: Hahm
authors.forename: Tae Sik
authors.initials: TS
authors.lastname: Jung
authors.forename: Hee Jin
authors.initials: HJ
authors.lastname: Kim
authors.forename: Ho Soo
authors.initials: HS
authors.lastname: Kim
authors.forename: Sungsu
authors.initials: S
authors.lastname: Kim
authors.forename: Soo Kyoung
authors.initials: SK
authors.lastname: Kim
authors.forename: Sang Min
authors.initials: SM
authors.lastname: Lee
authors.forename: Deok Ryong
authors.initials: DR
authors.lastname: Kim
authors.forename: Won Jun
authors.initials: WJ
authors.lastname: Choi
authors.forename: Yeong Mi
authors.initials: YM
authors.lastname: Seo
authors.forename: Soon Il
authors.initials: SI
authors.lastname: Chung
mesh_terms: D005260:Female; D006111:Graves Disease / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D006801:Humans; D007333:Insulin Resistance; D009839:Oligomenorrhea / Q000209:etiology; D011085:Polycystic Ovary Syndrome / Q000150:complications* / Q000175:diagnosis; D013851:Thinness / Q000150:complications; D055815:Young Adult