title: [HIFU for prostate cancer in patients with a history of severe colorectal disease].
abstract: OBJECTIVE
  To report the functional and oncological outcomes of HIFU for prostate cancer in patients with a history of severe colorectal disease.
  
  
  METHODS
  Between 2002 and 2009, 14 patients with a history of severe colorectal disease (cancer, lymphoma, inflammatory bowel diseases [IBD]) were treated with HIFU as a primary care option for localized prostate cancer.
  
  
  RESULTS
  Mean age was 65.8 ± 6.1 years. Mean time between colorectal disease treatment and HIFU was 10.6 ± 6.8 years. The mean Prostate Specific Antigen (PSA) before HIFU was 12.1 ng/mL (4.5-55). Gleason score was inferior or equal to 6 in four patients (28.6%), equal to 7 in nine patients (64.3%) and superior or equal to 8 in one patient (7.1%). The mean prostate volume before HIFU was 22.1 ± 11.7 mL. The number of HIFU sessions per patient was 1.35. The mean nadir PSA was 0.61 ± 0.82 ng/mL. Systematic control biopsies were negative in seven patients (50%). Mean follow-up was 22 months with a 35.7% complication rate (three erectile dysfunctions, two urinary stress incontinences). No recto-urethral fistula occurred.
  
  
  CONCLUSIONS
  HIFU was an interesting therapy for patients with a history of colorectal disease for whom regular treatment was challenging or non feasible.
authors.affiliation: Service d'urologie et chirurgie de la transplantation, hôpital Édouard-Herriot, Lyon, France. mitach2@yahoo.fr
authors.forename: A
authors.initials: A
authors.lastname: Mitach
authors.forename: S
authors.initials: S
authors.lastname: Crouzet
authors.forename: L
authors.initials: L
authors.lastname: Poissonier
authors.forename: O
authors.initials: O
authors.lastname: Rouvière
authors.forename: F
authors.initials: F
authors.lastname: Mege-Lechevallier
authors.forename: M
authors.initials: M
authors.lastname: Colombel
authors.forename: X
authors.initials: X
authors.lastname: Martin
authors.forename: A
authors.initials: A
authors.lastname: Gelet
mesh_terms: D000368:Aged; D003424:Crohn Disease / Q000150:complications*; D005240:Feasibility Studies; D057086:High-Intensity Focused Ultrasound Ablation; D006801:Humans; D008297:Male; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000150:complications*; D011446:Prospective Studies; D011471:Prostatic Neoplasms / Q000150:complications* / Q000601:surgery*; D012004:Rectal Neoplasms / Q000150:complications*; D012720:Severity of Illness Index