title: A case of naturally evolving gout in an elderly man.
abstract: Gout is a common disorder in adults that can lead to severe organ decline, disability and impaired quality of life due to the formation of periarticular tophi. We report a case of massive tophaceous gout in a 78-year-old man with a 16-year-long history of untreated disease. The patient gradually became disabled, his renal function deteriorated, and he finally died of sepsis. Our case demonstrates that chronic gout not only affects the joints, but is also associated with organ function decline and can, even nowadays, lead to death.
authors.affiliation: Department of Medical and Surgical Sciences, Geriatric Division, University of Padova, Italy.
authors.forename: Francesco
authors.initials: F
authors.lastname: Bolzetta
authors.forename: Nicola
authors.initials: N
authors.lastname: Veronese
authors.forename: Marco
authors.initials: M
authors.lastname: Mosele
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Sergi
authors.forename: Enzo
authors.initials: E
authors.lastname: Manzato
authors.forename: Valter
authors.initials: V
authors.lastname: Giantin
mesh_terms: D058186:Acute Kidney Injury / Q000628:therapy; D000368:Aged; D000493:Allopurinol / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D018771:Arthralgia / Q000188:drug therapy; D002908:Chronic Disease; D003078:Colchicine / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D017809:Fatal Outcome; D006073:Gout / Q000150:complications* / Q000188:drug therapy*; D006074:Gout Suppressants / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008775:Methylprednisolone / Q000627:therapeutic use; D051346:Mobility Limitation; D011788:Quality of Life; D006435:Renal Dialysis; D012131:Respiratory Insufficiency / Q000209:etiology; D018805:Sepsis / Q000188:drug therapy / Q000382:microbiology; D012720:Severity of Illness Index
chemical_list: D000900:Anti-Bacterial Agents; D006074:Gout Suppressants; D000493:Allopurinol; D003078:Colchicine; D008775:Methylprednisolone