title: Italian intersociety consensus statement on antithrombotic prophylaxis in hip and knee replacement and in femoral neck fracture surgery.
abstract: Anticoagulant prophylaxis for preventing venous thrombembolism (VTE) is a worldwide established procedure in hip (HR) and knee replacement (KR) surgery, as well as in the treatment of femoral neck fractures (FNF). Different guidelines are available in the literature, with quite different recommendations. None of them is a multidisciplinary effort as the one presented. The Italian Society for Studies on Hemostasis and Thrombosis, the Italian Society of Orthopedics and Traumatology, the association of Orthopedic Traumatology of Italian Hospitals, together with the Italian Society of Anesthesia, Analgesia, Resuscitation, and Intensive Care have set down easy and quick suggestions for VTE prophylaxis in HR and KR surgery as well as in FNF treatment. This inter-society consensus statement aims at simplifying the grading system reported in the literature, and thus at improving its proper application. Special focus is given to fragile patients, those with high bleeding risk, and on those receiving chronic antiplatelet and vitamin K antagonists treatment. A special chapter is dedicated to regional anesthesia and VTE prophylaxis.
authors.affiliation: Department of Anesthesia and Intensive Care Medicine, University of Udine, Italy. giorgio.dellarocca@uniud.it
authors.forename: G
authors.initials: G
authors.lastname: Della Rocca
authors.forename: F
authors.initials: F
authors.lastname: Biggi
authors.forename: P
authors.initials: P
authors.lastname: Grossi
authors.forename: D
authors.initials: D
authors.lastname: Imberti
authors.forename: R
authors.initials: R
authors.lastname: Landolfi
authors.forename: G
authors.initials: G
authors.lastname: Palareti
authors.forename: F
authors.initials: F
authors.lastname: Randelli
authors.forename: D
authors.initials: D
authors.lastname: Prisco
mesh_terms: D000758:Anesthesia; D019644:Arthroplasty, Replacement, Hip / Q000379:methods*; D019645:Arthroplasty, Replacement, Knee / Q000379:methods*; D032921:Consensus; D005265:Femoral Neck Fractures / Q000601:surgery*; D005343:Fibrinolytic Agents / Q000009:adverse effects / Q000627:therapeutic use*; D000077425:Fondaparinux; D006495:Heparin, Low-Molecular-Weight / Q000627:therapeutic use; D006801:Humans; D019637:Orthopedic Procedures / Q000379:methods; D061214:Patient Safety; D011134:Polysaccharides / Q000627:therapeutic use; D011183:Postoperative Complications / Q000517:prevention & control*; D019106:Postoperative Hemorrhage / Q000453:epidemiology / Q000628:therapy; D012306:Risk; D053828:Stockings, Compression; D013927:Thrombosis / Q000517:prevention & control*; D054556:Venous Thromboembolism / Q000453:epidemiology / Q000517:prevention & control; D014812:Vitamin K / Q000037:antagonists & inhibitors
chemical_list: D005343:Fibrinolytic Agents; D006495:Heparin, Low-Molecular-Weight; D011134:Polysaccharides; D014812:Vitamin K; D000077425:Fondaparinux