title: Electrophysiological analysis of heterologously expressed Kv and SK/IK potassium channels.
abstract: This unit describes protocols to aid investigators in determining the electrophysiological and pharmacological profile of heterologously expressed voltage or calcium-activated potassium channels belonging to the Kv1.x and SK/IK gene families. Protocols for data acquisition as well as analysis are provided.
authors.affiliation: Icagen, Durham, North Carolina, USA.
authors.forename: Neil A
authors.initials: NA
authors.lastname: Castle
authors.forename: Alan D
authors.initials: AD
authors.lastname: Wickenden
authors.forename: Anruo
authors.initials: A
authors.lastname: Zou
mesh_terms: D000818:Animals; D016466:CHO Cells; D006224:Cricetinae; D057809:HEK293 Cells; D006801:Humans; D051660:Intermediate-Conductance Calcium-Activated Potassium Channels / Q000187:drug effects / Q000502:physiology*; D008647:Mesocricetus; D018408:Patch-Clamp Techniques / Q000379:methods*; D051637:Shaker Superfamily of Potassium Channels / Q000187:drug effects / Q000502:physiology*
chemical_list: D051660:Intermediate-Conductance Calcium-Activated Potassium Channels; D051637:Shaker Superfamily of Potassium Channels