title: [Patient stratification: interactions between diagnosis and therapy].
abstract: There is a high interest in developing diagnostic tests, e.g. in terms of molecular markers. Usually diagnostic tests are judged by their accuracy. The benefit of diagnostic testing for the patient, though, can only derive from the received treatment after diagnosis. In this way, interaction between diagnostic testing and therapy is a prerequisite. In such cases diagnostic testing is predictive of therapy. To show its interaction, diagnostic tests should be embedded in randomised controlled trials.
authors.affiliation: Ruhr-Universität Bochum, Abteilung für Medizinische Informatik, Biometrie und Epidemiologie. trampisch@amib.rub
authors.forename: Hans
authors.initials: H
authors.lastname: Joachim Trampisch
authors.forename: Ulrike Sonja
authors.initials: US
authors.lastname: Trampisch
authors.forename: Ulrich
authors.initials: U
authors.lastname: Thiem
mesh_terms: D015415:Biomarkers; D003955:Diagnostic Tests, Routine; D019317:Evidence-Based Medicine; D006801:Humans; D025202:Molecular Diagnostic Techniques; D019547:Neck Pain / Q000534:rehabilitation; D010043:Outcome and Process Assessment, Health Care; D026741:Physical Therapy Modalities; D016032:Randomized Controlled Trials as Topic; D016896:Treatment Outcome
chemical_list: D015415:Biomarkers