title: Facile synthesis of Ag/GNS-g-PAA nanohybrids for antimicrobial applications.
abstract: A facile and efficient aqueous phase-based strategy to synthesize silver nanocrystal/graphene nanosheet (GNS) nanohybrids at room temperature, via in situ poly(acrylic acid) (PAA) grafting followed by attachment of Ag nanocrystals, was reported. In the presence of PAA-grafted GNSs, Ag nanoparticles were in situ generated from AgNO(3) aqueous solution without any additional reducing agent or complicated treatment. They readily attached to the GNS surfaces, leading to Ag/GNS-g-PAA nanohybrids. The products of the Ag/GNS-g-PAA nanohybrids were examined by transmission electron microscope, thermogravimetric analyzer, X-ray powder diffraction analyzer, and energy disperse spectroscopy. The Ag nanoparticles can be uniformly deposited on the surfaces of functionalized GNSs with a controlled size distribution of 4-8 nm. Furthermore, the Ag/GNS-g-PAA nanohybrids exhibit good antimicrobial activity against Gram-positive Staphylococcus aureus and Gram-negative Escherichia coli. The mean diameters of the zones of inhibition are 11.4 mm and 9.9 mm, respectively, for S. aureus and E. coli. The simplicity, efficiency and large-scale availability of nanohybrids combined with good antimicrobial activity make them attractive for graphene-based biomaterials.
authors.affiliation: State Key Laboratory of Solid Lubrication, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, China.
authors.forename: Zhixin
authors.initials: Z
authors.lastname: Tai
authors.forename: Haibin
authors.initials: H
authors.lastname: Ma
authors.forename: Bin
authors.initials: B
authors.lastname: Liu
authors.forename: Xingbin
authors.initials: X
authors.lastname: Yan
authors.forename: Qunji
authors.initials: Q
authors.lastname: Xue
mesh_terms: D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D006090:Gram-Negative Bacteria / Q000187:drug effects; D006094:Gram-Positive Bacteria / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D046529:Microscopy, Electron, Transmission; D049329:Nanostructures; D033362:Powder Diffraction; D012834:Silver / Q000737:chemistry*; D013059:Spectrum Analysis, Raman; D013818:Thermogravimetry
chemical_list: D000900:Anti-Bacterial Agents; D012834:Silver