title: Severe anaphylactic reaction to chlorhexidine during total hip arthroplasty surgery. A case report.
abstract: Two consecutive hip surgery procedures in the same patient were aborted following a severe anaphylactic reaction of the patient. After the second procedure, the patient was diagnosed to be allergic to chlorhexidine, a component of the gel used to insert a urinary catheter. Chlorhexidine allergy is rare, and the delayed presentation may make it easy to overlook. In hip arthroplasty surgery, this may result in an abandoned procedure and the need for re-operation.
authors.affiliation: Department of Orthopaedic Surgery, St. Anna Hospital, Geldrop, The Netherlands.
authors.forename: Thea
authors.initials: T
authors.lastname: Sijbesma
authors.forename: Heike
authors.initials: H
authors.lastname: Röckmann
authors.forename: Walter
authors.initials: W
authors.lastname: van der Weegen
mesh_terms: D000707:Anaphylaxis / Q000139:chemically induced* / Q000175:diagnosis; D000891:Anti-Infective Agents, Local / Q000009:adverse effects*; D019644:Arthroplasty, Replacement, Hip / Q000009:adverse effects*; D002710:Chlorhexidine / Q000009:adverse effects*; D004342:Drug Hypersensitivity / Q000209:etiology*; D006801:Humans; D007431:Intraoperative Complications / Q000139:chemically induced*; D008297:Male; D008875:Middle Aged; D014546:Urinary Catheterization / Q000009:adverse effects
chemical_list: D000891:Anti-Infective Agents, Local; D002710:Chlorhexidine