title: [Pulmonary Langerhans histiocytosis and Hodgkin's lymphoma].
abstract: Pulmonary Langerhans histiocytosis (PLH) is a rare disease due to the accumulation of Langerhans cells at the level of the bronchioles. These dendritic immunocytes form granulomata and destroy the wall of the airway. We report a case of PLH developing at the same time as Hodgkin's lymphoma in a young woman who smoked tobacco and cannabis. We observed a complete remission of the PLH lesions parallel to the remission of the Hodgkin's lymphoma after chemotherapy, in the absence of any change in the consumption of tobacco and cannabis. This observation leads us to discuss the potential relationships between PLH on one hand, and smoking, the lymphoma and its treatment on the other.
authors.affiliation: Département de pneumologie, CHU d'Angers, 4, rue Larrey, 49933 Angers cedex 9, France.
authors.forename: A
authors.initials: A
authors.lastname: Paris
authors.forename: M
authors.initials: M
authors.lastname: Dib
authors.forename: M-C
authors.initials: MC
authors.lastname: Rousselet
authors.forename: T
authors.initials: T
authors.lastname: Urban
authors.forename: A
authors.initials: A
authors.lastname: Tazi
authors.forename: F
authors.initials: F
authors.lastname: Gagnadoux
mesh_terms: D000063:Accidents, Traffic; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000627:therapeutic use; D001761:Bleomycin / Q000008:administration & dosage; D055745:Bronchioles / Q000473:pathology; D002330:Carmustine / Q000008:administration & dosage; D003561:Cytarabine / Q000008:administration & dosage; D003606:Dacarbazine / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage; D005047:Etoposide / Q000008:administration & dosage; D005260:Female; D006646:Histiocytosis, Langerhans-Cell / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology; D006689:Hodgkin Disease / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D007069:Ifosfamide / Q000008:administration & dosage; D033162:Incidental Findings; D008171:Lung Diseases / Q000150:complications* / Q000000981:diagnostic imaging / Q000188:drug therapy; D008206:Lymphatic Diseases / Q000000981:diagnostic imaging / Q000209:etiology; D008385:Marijuana Smoking / Q000009:adverse effects; D008558:Melphalan / Q000008:administration & dosage; D008775:Methylprednisolone / Q000008:administration & dosage; D008935:Mitoguazone / Q000008:administration & dosage; D012074:Remission Induction; D012907:Smoking / Q000009:adverse effects; D014057:Tomography, X-Ray Computed; D014747:Vinblastine / Q000008:administration & dosage / Q000031:analogs & derivatives; D014751:Vindesine / Q000008:administration & dosage; D000077235:Vinorelbine; D055815:Young Adult
chemical_list: D003561:Cytarabine; D001761:Bleomycin; D014747:Vinblastine; D005047:Etoposide; D003606:Dacarbazine; D004317:Doxorubicin; D008935:Mitoguazone; D008558:Melphalan; D000077235:Vinorelbine; D014751:Vindesine; D002330:Carmustine; D007069:Ifosfamide; D008775:Methylprednisolone