title: Prognostic value of preoperative radiological staging assessed by computed tomography in patients with nonmetastatic colon cancer.
abstract: OBJECTIVE
  This study evaluated the prognostic value of preoperative locoregional staging in patients with colon cancer and who underwent curative resection.
  
  
  METHODS
  A total of 536 consecutive patients who underwent curative resection for colon cancer from February 1999 to November 2007 were prospectively enrolled. The clinicopathological variables, including the radiological staging using computed tomography, were analyzed for the prognostic significance.
  
  
  RESULTS
  The 5-year overall survival rates of the patients with radiological T1, T2, T3, and T4 were 96%, 89%, 75%, and 79%, respectively (P = 0.028). The 5-year overall survival rates were 83%, 76%, and 54%, respectively, for patients with radiological N0, N1, and N2 disease (P < 0.001). The 5-year overall survival rates of the patients with radiological TNM (tumor-node-metastasis) stages I, II, and III were 90%, 81%, and 70%, respectively (P < 0.001) and the 5-year overall survival rates of the patients with pathological TNM stages I, II, and III were 93%, 80%, and 70%, respectively (P = 0.001). On multivariate analysis, the radiological T and N categories remained independent prognostic factors for both overall survival and disease-free survival.
  
  
  CONCLUSIONS
  Radiological staging is an independent predictor of long-term survival in the preoperative setting.
authors.affiliation: Departments of Surgery.
authors.forename: J W
authors.initials: JW
authors.lastname: Huh
authors.affiliation: Diagnostic Radiology, Chonnam National University Hwasun Hospital and Medical School, Gwangju, Korea.
authors.forename: Y Y
authors.initials: YY
authors.lastname: Jeong
authors.affiliation: Departments of Surgery. Electronic address: drkhr@chonnam.ac.kr.
authors.forename: H R
authors.initials: HR
authors.lastname: Kim
authors.affiliation: Departments of Surgery.
authors.forename: Y J
authors.initials: YJ
authors.lastname: Kim
mesh_terms: D000230:Adenocarcinoma / Q000000981:diagnostic imaging* / Q000401:mortality / Q000473:pathology* / Q000601:surgery; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003110:Colonic Neoplasms / Q000000981:diagnostic imaging* / Q000401:mortality / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D009364:Neoplasm Recurrence, Local / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D009367:Neoplasm Staging / Q000379:methods*; D011237:Predictive Value of Tests; D057234:Preoperative Period; D011379:Prognosis; D016019:Survival Analysis; D014057:Tomography, X-Ray Computed; D055815:Young Adult