title: In vitro fertilization and embryo transfer outcomes in relation to myometrial thickness.
abstract: OBJECTIVE
  To evaluate the effects of myometrial thickening on the outcomes of in vitro fertilization and embryo transfer (IVF-ET).
  
  
  METHODS
  Four hundred thirteen patients, a total of 551 IVF-ET cycles, were divided into group A (<2.00 cm), group B (2.00-2.49 cm), and group C (≥2.50 cm) based on myometrial thickness.
  
  
  RESULTS
  The implantation, clinical pregnancy, and live birth rates were significantly lower in group C. The abortion rates were significantly higher in group C. Among patients in group B, cases with other sonographic findings suggestive of adenomyosis, such as myometrial striations, heterogeneous myometrium, myometrial cysts, and poor definition of the endometrial-myometrial junction showed lower implantation, clinical pregnancy, live birth rates, and higher abortion rates.
  
  
  CONCLUSIONS
  Myometrial thickening of more than 2.50 cm on TVUS exerts overall adverse effects on IVF-ET outcomes. Even with mild thickening (2.00-2.49 cm), the presence of sonographic findings suggestive of adenomyosis is associated with adverse outcomes of IVF-ET.
authors.affiliation: Department of Obstetrics and Gynecology, Wonju Christian Hospital, Yonsei University Wonju College of Medicine, 162 Ilsan-dong, Wonju, Gangwon-do, 220-701, Republic of Korea.
authors.forename: Hyun Sik
authors.initials: HS
authors.lastname: Youm
authors.forename: Young Sik
authors.initials: YS
authors.lastname: Choi
authors.forename: Hyuck Dong
authors.initials: HD
authors.lastname: Han
mesh_terms: D000028:Abortion, Induced / Q000706:statistics & numerical data; D000328:Adult; D004624:Embryo Transfer; D004715:Endometriosis / Q000000981:diagnostic imaging / Q000473:pathology; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D009215:Myometrium / Q000000981:diagnostic imaging* / Q000473:pathology*; D011247:Pregnancy; D011248:Pregnancy Complications; D011256:Pregnancy Outcome / Q000453:epidemiology; D018873:Pregnancy Rate; D012189:Retrospective Studies; D014463:Ultrasonography