title: [Breast cancer in Mexican women under 40].
abstract: BACKGROUND
  Breast cancer is the leading cause of death from malignancy in women. The incidence increases with age, but the relationship between age and survival of breast cancer patients is not well defined. It is observed that young women with breast cancer have patterns more aggressive biological.
  
  
  OBJECTIVE
  To determine the frequency, sociodemographic, clinical and histopathological features of breast cancer in women under 40 years attending a specialist breast unit in Mexico City.
  
  
  METHODS
  Transversal, descriptive and retrospective study of patients under 40 years of age with breast cancer treated between 2005 and 2010.
  
  
  RESULTS
  1430 cases were diagnosed with breast cancer five years with a mean age of 53.64 +/- 11.87 years (range 23 to 93 years), 142 cases were women under 40 years of age (10%). The auto-detection of a breast lump was the most frequent clinical manifestation (50%).
  
  
  CONCLUSIONS
  The prevalence of clinical stage III in this age group suggests the difficulty of diagnosis, the high breast density, which is one factor limiting studies of screening with mammography, it diminishes their effectiveness in early detection of breast cancer.
authors.affiliation: Instituto de Enfermedades de la Mama FUCAM (IEM-FUCAM).
authors.forename: Javier
authors.initials: J
authors.lastname: Robles-Castillo
authors.forename: Eva
authors.initials: E
authors.lastname: Ruvalcaba-Limón
authors.forename: Antonio
authors.initials: A
authors.lastname: Maffuz
authors.forename: Sergio
authors.initials: S
authors.lastname: Rodríguez-Cuevas
mesh_terms: D000328:Adult; D017677:Age Distribution; D017668:Age of Onset; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001943:Breast Neoplasms / Q000000981:diagnostic imaging / Q000453:epidemiology* / Q000628:therapy; D018270:Carcinoma, Ductal, Breast / Q000000981:diagnostic imaging / Q000453:epidemiology* / Q000628:therapy; D018275:Carcinoma, Lobular / Q000000981:diagnostic imaging / Q000453:epidemiology* / Q000601:surgery / Q000628:therapy; D017024:Chemotherapy, Adjuvant / Q000706:statistics & numerical data; D003131:Combined Modality Therapy; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008327:Mammography; D008408:Mastectomy / Q000379:methods; D008800:Mexico / Q000453:epidemiology; D008875:Middle Aged; D009376:Neoplasms, Hormone-Dependent / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000628:therapy; D010052:Ovariectomy / Q000706:statistics & numerical data; D015995:Prevalence; D018714:Radiotherapy, Adjuvant / Q000706:statistics & numerical data; D012189:Retrospective Studies; D012307:Risk Factors; D012959:Socioeconomic Factors; D055815:Young Adult