title: [Antitachycardia and resynchronization devices  in the treatment of heart failure and prevention of  sudden death].
abstract: According to the modern ideas of the heart failure pathogenesis the noticeable contribution introduces ventricular dissynchrony which essence consists of the electrical and mechanical dissociation of different segments of the myocardium. In recent years the new method of cardiac resynchronization therapy has been worked out and achived good results. Its main purpose is the resynchronization of the heart by three-chamber or biventricular stimulation, which leads to an improvement of the effectiveness of heart activity. At the same time implanted cardioverter-defibrillator systems are actively used in the complex treatment of heart failure as a mean of sudden cardiac death prevention. In this article we present results of main international studies, which reveal clinical effectiveness of both methods for decreasing total mortality and frequency of hospitalizations, prolonging life span, and improving quality of life.
authors.forename: O V
authors.initials: OV
authors.lastname: Sapel'nikov
authors.forename: R S
authors.initials: RS
authors.lastname: Latypov
authors.forename: I R
authors.initials: IR
authors.lastname: Grishin
authors.forename: Iu V
authors.initials: IuV
authors.lastname: Mareev
authors.forename: M A
authors.initials: MA
authors.lastname: Saidova
authors.forename: R S
authors.initials: RS
authors.lastname: Akchurin
mesh_terms: D058406:Cardiac Resynchronization Therapy / Q000379:methods*; D058409:Cardiac Resynchronization Therapy Devices; D016757:Death, Sudden, Cardiac / Q000209:etiology / Q000517:prevention & control*; D017147:Defibrillators, Implantable; D004554:Electric Countershock / Q000295:instrumentation / Q000379:methods*; D006333:Heart Failure / Q000150:complications / Q000401:mortality / Q000503:physiopathology / Q000628:therapy; D006352:Heart Ventricles / Q000503:physiopathology; D006801:Humans; D016032:Randomized Controlled Trials as Topic; D017180:Tachycardia, Ventricular / Q000209:etiology / Q000503:physiopathology / Q000628:therapy*; D016896:Treatment Outcome