title: Stent implantation in aorto-ostial lesions: long-term follow-up and predictors of outcome.
abstract: OBJECTIVE
  To compare the outcomes of drug-eluting (DES) vs. bare-metal (BMS) stents for stenting of native aorto-ostial lesions (AOL) and to identify predictors of major adverse cardio and cerebrovascular events (MACCE).
  
  
  RESULTS
  A total of 181 patients (182 AOL) who underwent stenting of AOL were retrospectively identified: right-coronary artery in 130 (71.4%), left main in 52 (28.6%). In-hospital event rate was 1.1% (two non-Q-wave myocardial infarctions). Follow-up was possible in 98.3%, median time=23.9 months (IQR 12.1-37.7). Event rates and survival MACCE-free were not significantly different between DES and BMS. After multivariate analysis, only the logistic EuroSCORE >10% predicted MACCE (HR=4.66, 95% CI: 2.38-9.12, p<0.001), whereas the predictors for TLR were age (HR=0.96, 95% CI: 0.92-1.00, p=0.039) and the stented artery (RCA vs. LM, HR=10.2, 95% CI: 1.37-75.45, p=0.024).
  
  
  CONCLUSIONS
  AOL stenting can be performed with high success and low complication rates. At follow-up, no significant differences in event rates were found between DES and BMS; EuroSCORE>10% was the only predictor of MACCE.
authors.affiliation: Clinique Pasteur, Toulouse, France. andrecoimbraluz@hotmail.com
authors.forename: André
authors.initials: A
authors.lastname: Luz
authors.forename: Christine
authors.initials: C
authors.lastname: Hughes
authors.forename: Rui
authors.initials: R
authors.lastname: Magalhães
authors.forename: Teodoro
authors.initials: T
authors.lastname: Bisceglia
authors.forename: Fleur
authors.initials: F
authors.lastname: Descoutures
authors.forename: Khalid
authors.initials: K
authors.lastname: Tamamm
authors.forename: Didier
authors.initials: D
authors.lastname: Tchetche
authors.forename: Antoine
authors.initials: A
authors.lastname: Sauguet
authors.forename: Bruno
authors.initials: B
authors.lastname: Farah
authors.forename: Jean
authors.initials: J
authors.lastname: Fajadet
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D017130:Angioplasty / Q000379:methods*; D001018:Aortic Diseases / Q000175:diagnosis* / Q000401:mortality / Q000628:therapy*; D054855:Drug-Eluting Stents; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D008137:Longitudinal Studies; D008297:Male; D008670:Metals; D008875:Middle Aged; D015999:Multivariate Analysis; D009203:Myocardial Infarction / Q000453:epidemiology; D011379:Prognosis; D016016:Proportional Hazards Models; D012189:Retrospective Studies; D015607:Stents; D020521:Stroke / Q000453:epidemiology; D015996:Survival Rate; D016896:Treatment Outcome
chemical_list: D008670:Metals