title: [MicroRNA-29 and fibrosis diseases].
abstract: MicroRNAs (miRNAs,miR) are small, noncoding RNAs with 21-23 nucleotides. MicroRNA-29 (miR-29), a newly discovered miRNAs, is closely related with fibrosis diseases. MiR-29 directly suppresses the expression of a variety of extracellular matrix components and regulates signaling pathways associated with fibrosis. The serum level of miR-29 in patients with liver disease is consistent with the degree of liver cirrhosis.
authors.affiliation: Department of Nephropathy, Central South University, Changsha, China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Ge
authors.forename: Guochun
authors.initials: G
authors.lastname: Chen
authors.forename: Lin
authors.initials: L
authors.lastname: Sun
authors.forename: Fuyou
authors.initials: F
authors.lastname: Liu
mesh_terms: D005109:Extracellular Matrix / Q000235:genetics* / Q000378:metabolism; D006801:Humans; D008103:Liver Cirrhosis / Q000097:blood* / Q000235:genetics; D035683:MicroRNAs / Q000097:blood* / Q000235:genetics; D015398:Signal Transduction
chemical_list: C532045:MIRN29a microRNA, human; D035683:MicroRNAs