title: Intrinsic curvature: a marker of millimeter-scale tangential cortico-cortical connectivity?
abstract: In this paper, we draw a link between cortical intrinsic curvature and the distributions of tangential connection lengths. We suggest that differential rates of surface expansion not only lead to intrinsic curvature of the cortical sheet, but also to differential inter-neuronal spacing. We propose that there follows a consequential change in the profile of neuronal connections: specifically an enhancement of the tendency towards proportionately more short connections. Thus, the degree of cortical intrinsic curvature may have implications for short-range connectivity.
authors.affiliation: Brain Mapping Unit, Department of Psychiatry, University of Cambridge, Cambridge, UK. lr344@cam.ac.uk
authors.forename: Lisa
authors.initials: L
authors.lastname: Ronan
authors.forename: Rudolph
authors.initials: R
authors.lastname: Pienaar
authors.forename: Guy
authors.initials: G
authors.lastname: Williams
authors.forename: Ed
authors.initials: E
authors.lastname: Bullmore
authors.forename: Tim J
authors.initials: TJ
authors.lastname: Crow
authors.forename: Neil
authors.initials: N
authors.lastname: Roberts
authors.forename: Peter B
authors.initials: PB
authors.lastname: Jones
authors.forename: John
authors.initials: J
authors.lastname: Suckling
authors.forename: Paul C
authors.initials: PC
authors.lastname: Fletcher
mesh_terms: D000818:Animals; D002540:Cerebral Cortex / Q000033:anatomy & histology*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008953:Models, Anatomic; D009434:Neural Pathways / Q000033:anatomy & histology*; D009474:Neurons / Q000166:cytology; D002679:Pan troglodytes / Q000033:anatomy & histology; D015203:Reproducibility of Results; D014894:Weights and Measures