title: Arterial thrombosis and acute myocardial infarction with angiographically normal coronary arteries in a woman heterozygous for both factor V Leiden and prothrombin mutation.
abstract: Thirteen years after her last thrombotic event, anticoagulation was discontinued in a patient with combined thrombophilia involving mutation in factor V and G20210A polymorphism of the prothrombin gene. The only history was of arterial thrombosis. Three months later she presented a transmural myocardial infarction caused by coronary thrombosis.
authors.affiliation: Hospital de Ipanema, Hospital Samaritano, Rio de Janeiro, Brazil.
authors.forename: João
authors.initials: J
authors.lastname: Gaspar
authors.forename: Cláudio
authors.initials: C
authors.lastname: Benchimol
authors.forename: Telma
authors.initials: T
authors.lastname: Gadelha
authors.forename: Guilherme Loures
authors.initials: GL
authors.lastname: Penna
mesh_terms: D017023:Coronary Angiography; D003328:Coronary Thrombosis / Q000150:complications* / Q000235:genetics*; D005165:Factor V / Q000235:genetics*; D005260:Female; D006579:Heterozygote; D006801:Humans; D008875:Middle Aged; D009154:Mutation; D009203:Myocardial Infarction / Q000150:complications* / Q000235:genetics*; D011516:Prothrombin / Q000235:genetics*
chemical_list: C095381:factor V Leiden; D005165:Factor V; D011516:Prothrombin