title: [Predictive value C-reactive protein assessment level in women with arterial hypertension].
abstract: Classic modifiable cardiovascular risk factors, such as blood pressure and dyslipidaemia are incorporated into clinical practice to estimate the 10-year risk of fatal cardiovascular disease (CVD): the SCORE project. To improve CVD risk estimation in women we compared predictive value of two models: risk chart based on the SCORE study and the Reynolds Risk Score in 134 women with hypertension to optimise risk stratification and preventive strategies in high-risk individuals. We concluded that Reynolds Risk model causes clinically relevant changes in risk category classification compared to risk chart SCORE and improves risk stratification. Addition of C-reactive protein to Reynolds Risk model improves it predictive value regardless of other risk factors. C-reactive protein is a strong marker of atherosclerosis, can be useful in women for risk stratification in daily practice regardless of risk prediction model.
authors.forename: E M
authors.initials: EM
authors.lastname: Andrievskaia
authors.forename: A Ia
authors.initials: AIa
authors.lastname: Ivleva
authors.forename: E S
authors.initials: ES
authors.lastname: Minina
authors.forename: O E
authors.initials: OE
authors.lastname: Lagutina
mesh_terms: D050197:Atherosclerosis / Q000097:blood* / Q000150:complications; D015415:Biomarkers; D001795:Blood Pressure Determination; D002097:C-Reactive Protein / Q000032:analysis*; D002318:Cardiovascular Diseases / Q000097:blood* / Q000209:etiology / Q000401:mortality; D015150:Echocardiography, Doppler; D004562:Electrocardiography; D005260:Female; D006801:Humans; D006973:Hypertension / Q000097:blood* / Q000150:complications / Q000175:diagnosis; D008875:Middle Aged; D008991:Monitoring, Physiologic / Q000379:methods / Q000592:standards*; D017410:Practice Guidelines as Topic; D011237:Predictive Value of Tests; D018570:Risk Assessment; D012307:Risk Factors
chemical_list: D015415:Biomarkers; D002097:C-Reactive Protein