title: Leptin, adiponectin and other adipokines in gestational diabetes mellitus and pre-eclampsia.
abstract: Proteins secreted from adipocytes - so-called adipokines - influence metabolic and vascular function. Recent data suggest that various adipokines are dysregulated in gestational diabetes mellitus (GDM) and pre-eclampsia (PE) and might be of pathophysiological and prognostic significance in these complications of pregnancy. This review gives an overview on the regulation and pathophysiology of leptin and adiponectin in GDM and PE. Furthermore, data on novel adipokines including resistin, visfatin, retinol-binding protein 4 and vaspin are summarized.
authors.affiliation: Department of Internal Medicine (Endocrinology and Nephrology), University of Leipzig, Germany.
authors.forename: Konstanze
authors.initials: K
authors.lastname: Miehle
authors.forename: Holger
authors.initials: H
authors.lastname: Stepan
authors.forename: Mathias
authors.initials: M
authors.lastname: Fasshauer
mesh_terms: D052242:Adiponectin / Q000235:genetics / Q000378:metabolism*; D016640:Diabetes, Gestational / Q000378:metabolism*; D005260:Female; D006801:Humans; D020738:Leptin / Q000235:genetics / Q000378:metabolism*; D011225:Pre-Eclampsia / Q000378:metabolism*; D011247:Pregnancy
chemical_list: D052242:Adiponectin; D020738:Leptin