title: Evaluation of different fluoride concentrations supplemented with trimetaphosphate on enamel de- and remineralization in vitro.
abstract: Trimetaphosphate (TMP) effects on demineralized bovine enamel were studied after 15 days of pH cycling. Treatments included 30 wt% (weight percent) dilutions of 0, 500, 1,500 or 3,000 μg F/g aqueous NaF solutions with or without 3% TMP. Treated specimens were assessed by transverse microradiography. With the exception of the 3,000 μg F/g case, 3% TMP addition provided significant additional overall remineralization compared with F alone. Mineral content profiles differed significantly between corresponding F and F + TMP groups. Fluoride alone resulted in more remineralization in the original demineralized zone, whereas F + TMP caused less demineralization in the underlying, originally sound enamel.
authors.affiliation: Department of Cariology Endodontology Pedodontology, Academic Center for Dentistry Amsterdam, University of Amsterdam and Free University, Amsterdam, The Netherlands. elimitsue@yahoo.com.br
authors.forename: E M
authors.initials: EM
authors.lastname: Takeshita
authors.forename: R A M
authors.initials: RA
authors.lastname: Exterkate
authors.forename: A C B
authors.initials: AC
authors.lastname: Delbem
authors.forename: J M
authors.initials: JM
authors.lastname: ten Cate
mesh_terms: D000818:Animals; D002327:Cariostatic Agents / Q000008:administration & dosage*; D002417:Cattle; D011232:Chemical Precipitation; D003460:Crystallization; D003743:Dental Enamel / Q000187:drug effects* / Q000473:pathology; D004338:Drug Combinations; D006863:Hydrogen-Ion Concentration; D008852:Microradiography; D008903:Minerals / Q000032:analysis; D011122:Polyphosphates / Q000008:administration & dosage*; D012969:Sodium Fluoride / Q000008:administration & dosage*; D013997:Time Factors; D017001:Tooth Demineralization / Q000503:physiopathology*; D014089:Tooth Remineralization / Q000379:methods*
chemical_list: D002327:Cariostatic Agents; D004338:Drug Combinations; D008903:Minerals; D011122:Polyphosphates; D012969:Sodium Fluoride; C009293:trimetaphosphoric acid