title: Borna disease virus - fact and fantasy.
abstract: The occasion of Brian Mahy's retirement as editor of Virus Research provides an opportunity to reflect on the work that led one of the authors (Lipkin) to meet him shortly after the molecular discovery and characterization of Borna disease virus in the late 1980s, and work with authors Briese and Hornig to investigate mechanisms of pathogenesis and its potential role in human disease. This article reviews the history, molecular biology, epidemiology, and pathobiology of bornaviruses.
authors.affiliation: Center for Infection and Immunity, Columbia University Mailman School of Public Health, 722 W 168th St., 17th Floor, New York, NY 10032, United States. wil2001@columbia.edu
authors.forename: W Ian
authors.initials: WI
authors.lastname: Lipkin
authors.forename: Thomas
authors.initials: T
authors.lastname: Briese
authors.forename: Mady
authors.initials: M
authors.lastname: Hornig
mesh_terms: D000818:Animals; D001890:Borna Disease / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology / Q000473:pathology / Q000821:virology*; D001891:Borna disease virus / Q000235:genetics*; D001921:Brain / Q000473:pathology / Q000821:virology*; D002417:Cattle; D002418:Cattle Diseases / Q000175:diagnosis / Q000473:pathology / Q000821:virology*; D016679:Genome, Viral; D006734:Horse Diseases / Q000175:diagnosis / Q000473:pathology / Q000821:virology*; D006736:Horses; D006801:Humans; D012367:RNA, Viral / Q000235:genetics; D012559:Schizophrenia / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology / Q000473:pathology / Q000821:virology*; D012756:Sheep; D012757:Sheep Diseases / Q000175:diagnosis / Q000473:pathology / Q000821:virology*; D014481:United States / Q000453:epidemiology; D014771:Virion / Q000737:chemistry / Q000235:genetics; D014779:Virus Replication
chemical_list: D012367:RNA, Viral