title: A new benzodioxocinone from the leaves of Cinnamomum tenuifolium.
abstract: Investigation of the leaves' extract of Cinnamomum tenuifolium (Lauraceae) led to the isolation of one novel benzodioxocinone, 2,3-dihydro-6,6-dimethylbenzo-[b][1,5]dioxocin-4(6 H)-one (1). The structure was determined through in-depth spectroscopic and mass-spectrometric analyses. The antioxidant potential was evaluated using the following in vitro method: scavenging of 1,1-diphenyl-2-picrylhydrazyl radical. We also detected the anti-proliferative effect of 1 on human oral cancer cells and its IC(50) is 107.7 µM.
authors: School of Medical and Health Sciences, Fooyin University, Kaohsiung County, Taiwan, ROC.
authors: Hsin-Liang
authors: HL
authors: Chen
authors: Soong-Yu
authors: SY
authors: Kuo
authors: Yun-Ping
authors: YP
authors: Li
authors: Ya-Fei
authors: YF
authors: Kang
authors: Yu-Ting
authors: YT
authors: Yeh
authors: Jin-Cherng
authors: JC
authors: Huang
authors: Chung-Yi
authors: CY
authors: Chen
mesh_terms: D000975:Antioxidants / Q000737:chemistry* / Q000494:pharmacology*; D001713:Biphenyl Compounds / Q000737:chemistry; D045744:Cell Line, Tumor; D049109:Cell Proliferation / Q000187:drug effects; D027424:Cinnamomum / Q000737:chemistry*; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D010851:Picrates / Q000737:chemistry; D018515:Plant Leaves / Q000737:chemistry*
chemical_list: D000975:Antioxidants; D001713:Biphenyl Compounds; D010851:Picrates; C004931:1,1-diphenyl-2-picrylhydrazyl