title: [Results of fibrin clot application for acceleration of regeneration of the damaged mandible in experiment].
abstract: The processes of regeneration of the damaged rat bottom jaw bone after application of enriched thrombocytes a fibrin clot were studied by morphological and radiovisiographic methods. At a natural course of regeneration the artificial aperture of bone was filled with blood and there the blood clot was formed. After 1 week the separate bone islets of a young tissue occurred in bone defect. In 2-3 weeks the aperture in a bottom jaw bone was completely closed by a young bone tissue. After operation with filling of bone bottom jaw defect by fibrin clot there was no formation of a blood clot. Already after 1 week the bone tissue defect was filled by the merged islets of again generated bone. By second week after fibrin use the further formation of bone tissue in defect and formation of a bone callosity was noted.
authors: I V
authors: IV
authors: Maĭborodin
authors: I S
authors: IS
authors: Kolesnikov
authors: A I
authors: AI
authors: Shevela
authors: B V
authors: BV
authors: Sheplev
authors: M N
authors: MN
authors: Drovosekov
authors: M S
authors: MS
authors: Toder
mesh_terms: D000818:Animals; D001792:Blood Platelets / Q000502:physiology; D001861:Bone Regeneration / Q000187:drug effects*; D005338:Fibrin Fibrinogen Degradation Products / Q000008:administration & dosage*; D008297:Male; D008334:Mandible / Q000166:cytology / Q000502:physiology* / Q000601:surgery*; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D005338:Fibrin Fibrinogen Degradation Products