title: Switching on the deep brain stimulation: effects on cardiovascular regulation and respiration.
abstract: BACKGROUND
  Objective of this study was to evaluate the acute cardiovascular and respiratory effects of switching on the deep brain stimulation in the follow up of nine Parkinson's disease patients with subthalamic nucleus stimulation and six cluster headache patients with posterior hypothalamic area stimulation.
  
  
  METHODS
  Systolic and diastolic blood pressure, heart rate, and respiratory rate were monitored continuously during supine rest in both groups. Each patient was assessed in two conditions: resting supine with stimulator off and with stimulator on.
  
  
  RESULTS
  In supine resting condition switching on the DBS induced no significant changes (p>0.05) in systolic and diastolic blood pressure as well as in heart rate and respiratory rate, in both groups of patients, either taking 1 min or 10 heartbeats as a sample for analysis.
  
  
  CONCLUSIONS
  Switching on the DBS does not modify heart rate, blood pressure nor respiratory rate in both Parkinson and cluster headache patients under resting conditions.
authors: Department of Clinical Neurosciences, University of Palermo, Palermo, Italy. simone.vigneri@gmail.com
authors: S
authors: S
authors: Vigneri
authors: P
authors: P
authors: Guaraldi
authors: G
authors: G
authors: Calandra-Buonaura
authors: R
authors: R
authors: Terlizzi
authors: A
authors: A
authors: Cecere
authors: G
authors: G
authors: Barletta
authors: P
authors: P
authors: Cortelli
mesh_terms: D000328:Adult; D000368:Aged; D002320:Cardiovascular Physiological Phenomena; D003027:Cluster Headache / Q000503:physiopathology / Q000628:therapy*; D046690:Deep Brain Stimulation / Q000009:adverse effects* / Q000379:methods; D004567:Electrodes, Implanted / Q000009:adverse effects / Q000592:standards; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000503:physiopathology / Q000628:therapy*; D012143:Respiratory Physiological Phenomena