title: Modern-day challenges in therapeutic protein production.
abstract: The market for therapeutic proteins is on the rise, plagued by several challenges related to production amounts and costs. Solutions to these problems are widely thought to come from academia, governments and production companies. This conference aimed to bring experts in the industry together under one roof, in order to demystify several novel technologies in therapeutic protein development. Key topics included analytical tools for protein stability and ligand interactions, measurement of protein aggregates as small as 30 nm and reducing production costs, just to name a few. The need to eliminate protein aggregates early during bioprocessing was emphasized. Finally, several companies presented novel technologies related to therapeutic protein development.
authors: School of Chemical Engineering and Analytical Science, The University of Manchester, Oxford Road, Manchester, M13 9PL, UK. kennethfuh@yahoo.com
authors: Kenneth
authors: K
authors: Fuh
mesh_terms: D004345:Drug Industry; D006801:Humans; D055550:Protein Stability; D011506:Proteins / Q000737:chemistry / Q000191:economics* / Q000627:therapeutic use*
chemical_list: D011506:Proteins