title: [Long-term clarithromycin therapy in patients with chronic polypous rhinosinusitis].
abstract: Article is dedicated to therapeutic effect of long-term therapy clarithromycin in patients with varying severity of chronic polypous rhinosinusitis. The effectiveness of therapy based on monitoring of symptoms and quality of life on a scale of SNOT-20 in an open clinical trial in the treatment in patients with varying degrees of severity of chronic polypous rhino sinusitis with the macrolide Klaсid 500 SR was assessed in three months. As a result of investigations, good and excellent effect was observed mainly in patients with mild to moderate disease. Obviously, the duration of therapy should be in cases with severe forms of chronic polypous rhino sinusitismore than 3 months.
authors: FGU "Nauchno-klinicheskiĭ tsentr otorinolaringologii" FMBA Rossii, Moskva.
authors: M A
authors: MA
authors: Mokronosova
authors: Iu S
authors: IuS
authors: Kuian
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002908:Chronic Disease; D017291:Clarithromycin / Q000008:administration & dosage; D006801:Humans; D011788:Quality of Life; D012220:Rhinitis / Q000188:drug therapy; D012852:Sinusitis / Q000188:drug therapy
chemical_list: D000900:Anti-Bacterial Agents; D017291:Clarithromycin