title: Correlative magnetic resonance imaging and autopsy findings in a patient with coagulation necrosis treated with tissue plasminogen activator.
abstract: Coagulation necrosis is a peculiar type of ischemic necrosis that is characterized by firm, eosinophilic parenchyma with recognizable cell outlines without massive glial reactions. This is an autopsy report of coagulation necrosis 6 months after thrombolytic tissue plasminogen activator therapy against massive cerebral embolism in an 84-year-old man with atrial fibrillation.
authors: Department of Neurology, Tokyo Metropolitan Institute for Neuroscience, Tokyo, Japan. suzukimiki@nij.twmu.ac.jp
authors: Miki
authors: M
authors: Suzuki
authors: Toshiki
authors: T
authors: Uchihara
authors: Shuta
authors: S
authors: Toru
authors: Yuan
authors: Y
authors: Bae
authors: Toru
authors: T
authors: Igari
authors: Masanobu
authors: M
authors: Kitagawa
authors: Shinichiro
authors: S
authors: Uchiyama
authors: Katsuiku
authors: K
authors: Hirokawa
authors: Takayoshi
authors: T
authors: Kobayashi
mesh_terms: D000369:Aged, 80 and over; D001281:Atrial Fibrillation / Q000150:complications*; D001344:Autopsy; D001921:Brain / Q000187:drug effects / Q000473:pathology*; D017809:Fatal Outcome; D005343:Fibrinolytic Agents / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D020766:Intracranial Embolism / Q000188:drug therapy* / Q000209:etiology; D020300:Intracranial Hemorrhages / Q000139:chemically induced / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D008297:Male; D009336:Necrosis; D015912:Thrombolytic Therapy / Q000009:adverse effects*; D010959:Tissue Plasminogen Activator / Q000008:administration & dosage / Q000009:adverse effects*; D016896:Treatment Outcome
chemical_list: D005343:Fibrinolytic Agents; D010959:Tissue Plasminogen Activator