title: A conserved haplotype controls parallel adaptation in geographically distant salmonid populations.
abstract: Salmonid fishes exhibit extensive local adaptations owing to abundant environmental variation and precise natal homing. This extensive local adaptation makes conservation and restoration of salmonids a challenge. For example, defining unambiguous units of conservation is difficult, and restoration attempts often fail owing to inadequate adaptive matching of translocated populations. A better understanding of the genetic architecture of local adaptation in salmonids could provide valuable information to assist in conserving and restoring natural populations of these important species. Here, we use a combination of laboratory crosses and next-generation sequencing to investigate the genetic architecture of the parallel adaptation of rapid development rate in two geographically and genetically distant populations of rainbow trout (Oncorhynchus mykiss). Strikingly, we find that not only is a parallel genetic mechanism used but that a conserved haplotype is responsible for this intriguing adaptation. The repeated use of adaptive genetic variation across distant geographical areas could be a general theme in salmonids and have important implications for conservation and restoration.
authors: Institute of Molecular Biology and Howard Hughes Medical Institute, University of Oregon, Eugene, OR 97403, USA. miller.michael.ryan@gmail.com
authors: Michael R
authors: MR
authors: Miller
authors: Joseph P
authors: JP
authors: Brunelli
authors: Paul A
authors: PA
authors: Wheeler
authors: Sixin
authors: S
authors: Liu
authors: Caird E
authors: CE
authors: Rexroad
authors: Yniv
authors: Y
authors: Palti
authors: Chris Q
authors: CQ
authors: Doe
authors: Gary H
authors: GH
authors: Thorgaard
mesh_terms: D000222:Adaptation, Physiological / Q000235:genetics*; D000818:Animals; D003247:Conservation of Natural Resources; D014644:Genetic Variation; D023281:Genomics; D006239:Haplotypes; D017686:Oncorhynchus mykiss / Q000235:genetics; D058974:Phylogeography; D012487:Salmonidae / Q000235:genetics*; D017422:Sequence Analysis, DNA