title: In vivo evaluation of human skin anisotropy by polarization-sensitive optical coherence tomography.
abstract: We performed an in vivo three-dimensional analysis of anisotropic changes in the dermal birefringence of mechanically deformed human skin using polarization-sensitive optical coherence tomography (PS-OCT). The papillary-dermal birefringence of the forehead increased significantly when the skin was shrunk parallel to the body axis, and decreased significantly when the skin was shrunk perpendicular to the body axis. En-face images of the papillary-dermal birefringence revealed variations among individual subjects, and that both shrinking parallel to and stretching in perpendicular to the body axis promoted the formation of macro rope-like birefringent domains. We found that PS-OCT is useful for understanding anisotropic properties of collagen structure in the skin.
authors: Shingo
authors: S
authors: Sakai
authors: Masahiro
authors: M
authors: Yamanari
authors: Yiheng
authors: Y
authors: Lim
authors: Noriaki
authors: N
authors: Nakagawa
authors: Yoshiaki
authors: Y
authors: Yasuno