title: Morphological changes of the vocal fold mucosa in hyperfunctional dysphonia diagnosed by psychoacoustic and videostroboscopic methods.
abstract: OBJECTIVE
  The aim of the study was to provide a morphological assessment of the laryngeal mucosa in patients with hyperfunctional dysphonia diagnosed by psychoacoustic and videostroboscopic methods.
  
  
  METHODS
  Forty patients with voice quality disorders of hyperfunctional dysphonia were recruited for participation in the study. The diagnosis of dysphonia was based on the Voice Rating Scale GRBAS, and endoscopic and stroboscopic assessment of the vocal folds. Acoustic assessment was carried out using following parameters: fundamental frequency, Jitter, Shimmer, Noise to Harmonic Rate and Yanagihara (YG) scale. In order to evaluate the morphology of the vocal fold mucosa transmission electron microscopy was performed using postoperative material obtained from the larynx. Results of clinical and morphological analysis were compared with the reference group. The morphological material was obtained from patients with hypopharyngeal cancer without pathological changes of the vocal folds.
  
  
  RESULTS
  The psychoacoustic assessment using the perceptual GRBAS scale enables the appropriate diagnostics of hyperfunctional dysphonia, which was confirmed by evaluation of acoustic parameters and YG scale analysis. In 40 patients with voice quality disorders causing by hyperfunctional dysphonia, in morphological assessment of the laryngeal mucosa, 4 (10%) patients demonstrated the presence of oedema and signs of intensive dysphonia in psychoacoustic and stroboscopic examination.
  
  
  CONCLUSIONS
  Oedema of the laryngeal mucosa confirmed by stroboscopic and ultramorphological examination may coexist with hyperfunctional dysphonia. The presence of the laryngeal oedema in patients with hyperfunctional dysphonia has the negative impact on voice quality in psychoacoustic assessment with the use of the GRBAS and YG scales.
authors: Department of Clinical Phonoaudiology and Logopedics, Medical University of Bialystok, Bialystok, Poland. fono@umwb.edu.pl
authors: B
authors: B
authors: Kosztyła-Hojna
authors: D
authors: D
authors: Moskal
authors: A
authors: A
authors: Kuryliszyn-Moskal
authors: A
authors: A
authors: Andrzejewska
authors: D
authors: D
authors: Falkowski
mesh_terms: D000162:Acoustics; D000328:Adult; D004487:Edema / Q000473:pathology; D004724:Endoscopy / Q000379:methods; D005260:Female; D006801:Humans; D007820:Laryngeal Mucosa / Q000473:pathology; D007830:Larynx / Q000473:pathology; D008297:Male; D046529:Microscopy, Electron, Transmission / Q000379:methods; D008875:Middle Aged; D011571:Psychoacoustics; D012016:Reference Values; D015203:Reproducibility of Results; D049489:Stroboscopy / Q000379:methods*; D014827:Vocal Cords / Q000503:physiopathology*; D014832:Voice Disorders / Q000175:diagnosis* / Q000473:pathology