title: Lipoprotein profiles in Mexican American and non-Hispanic white women with polycystic ovary syndrome.
abstract: OBJECTIVE
  To compare lipid profiles between Mexican American and non-Hispanic white women with polycystic ovary syndrome (PCOS).
  
  
  METHODS
  Cross-sectional analysis using the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) guidelines.
  
  
  METHODS
  University gynecology service.
  
  
  METHODS
  Self-identified Mexican Americans (n = 71) and non-Hispanic whites (n = 120) with PCOS defined by the 2003 European Society of Human Reproduction and Embryology and American Society of Reproductive Medicine consensus.
  
  
  METHODS
  Serum drawn from fasting state followed by oral glucose tolerance test.
  
  
  METHODS
  Age, body mass index (BMI), androgens, cholesterol, triglycerides, HDL cholesterol, LDL cholesterol, fasting, and minimal model analyses of insulin sensitivity.
  
  
  RESULTS
  Mexican American women were more insulin resistant than non-Hispanic whites, but cholesterol, triglycerides, HDL cholesterol, LDL cholesterol, and calculated non-HDL cholesterol levels were similar. BMI inversely correlated with HDL cholesterol and positively with triglycerides. Approximately half of both ethnic groups had at least one lipid level in the low (HDL) or high (cholesterol, triglycerides, and LDL cholesterol) range according to National Cholesterol Education Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults guidelines.
  
  
  CONCLUSIONS
  Despite greater insulin resistance among Mexican Americans with PCOS, lipid levels were similar to those of age- and weight-matched non-Hispanic whites. Obesity adversely affected lipid levels-primarily HDL cholesterol and triglycerides-in both groups. The prevalence of dyslipidemia was approximately 50% in each ethnic group.
authors: Department of Obstetrics and Gynecology, Texas Tech University Health Science Center School of Medicine at Amarillo, Amarillo, Texas 79106, USA. robert.kauffman@ttuhsc.edu
authors: Robert P
authors: RP
authors: Kauffman
authors: Teresa E
authors: TE
authors: Baker
authors: Kory
authors: K
authors: Graves-Evenson
authors: Vicki M
authors: VM
authors: Baker
authors: V Daniel
authors: VD
authors: Castracane
mesh_terms: D000328:Adult; D015992:Body Mass Index; D008078:Cholesterol, LDL / Q000097:blood; D003430:Cross-Sectional Studies; D005260:Female; D005951:Glucose Tolerance Test; D006801:Humans; D007328:Insulin / Q000097:blood; D007333:Insulin Resistance; D008074:Lipoproteins / Q000097:blood* / Q000378:metabolism; D055442:Metabolome / Q000502:physiology; D017058:Mexican Americans / Q000706:statistics & numerical data; D011085:Polycystic Ovary Syndrome / Q000097:blood* / Q000453:epidemiology / Q000208:ethnology* / Q000378:metabolism; D044465:White People / Q000706:statistics & numerical data
chemical_list: D008078:Cholesterol, LDL; D007328:Insulin; D008074:Lipoproteins