title: [The use of exogenous nitrogen monoxide for the prophylaxis of postoperative wound infection].
abstract: The study covers treatment results of 220 patients operated on ventral hernia and in vivo experimental treatment of 36 rats proved the nitrogen monoxide (NO) to be the effective means of wound infection prophylaxis. NO potentiates antiseptic effects, minimizing intraoperative wound contamination. It, besides, stimulates endothelial and basal cells of epidermis proliferation. Wound infection was observed only in 9,8% of patients, treated with NO intraoperatively. All cases of infective complications were serous and infiltrative, but not purulent.
authors: A B
authors: AB
authors: Larichev
authors: V K
authors: VK
authors: Shishlo
authors: A V
authors: AV
authors: Lisovskiĭ
authors: A L
authors: AL
authors: Chistiakov
mesh_terms: D000328:Adult; D000818:Animals; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000493:pharmacokinetics; D000891:Anti-Infective Agents, Local / Q000008:administration & dosage / Q000493:pharmacokinetics; D019072:Antibiotic Prophylaxis / Q000379:methods / Q000592:standards; D001682:Biological Availability; D004202:Disinfectants / Q000494:pharmacology; D004866:Equipment Contamination / Q000517:prevention & control; D005260:Female; D006097:Granulation Tissue / Q000187:drug effects / Q000378:metabolism; D006555:Hernia, Ventral / Q000601:surgery*; D006801:Humans; D008297:Male; D008991:Monitoring, Physiologic; D018919:Neovascularization, Physiologic / Q000187:drug effects*; D009569:Nitric Oxide / Q000008:administration & dosage / Q000493:pharmacokinetics; D051381:Rats; D013530:Surgical Wound Infection / Q000378:metabolism / Q000517:prevention & control*; D016896:Treatment Outcome; D014945:Wound Healing / Q000187:drug effects*
chemical_list: D000900:Anti-Bacterial Agents; D000891:Anti-Infective Agents, Local; D004202:Disinfectants; D009569:Nitric Oxide