title: [Analysis of flavonoids in platycladi cacumen by UPLC-MS].
abstract: OBJECTIVE
  To investigate the flavonoids in Platycladi Cacumen.
  
  
  METHODS
  The constituents in Platycladi Cacumen were determined by UPLC-MS. A Waters BEH C18 column (2.1 mm x 150 mm, 1.7 microm) was used with a gradient elution of methanol-water containing 0.2% formic acid. The mass spectrometer equipped with electrospay ionization source was used as defector and operated in data was collected under the negative ion modes.
  
  
  RESULTS
  Eleven constituents were identified.
  
  
  CONCLUSIONS
  In this study, the main flavonoids in Platycladi Cacumen were separated by UPLC, and identified through the information of mass number and UV spectra. With the information of MS/MS from flavonoids, the modes of breaking up flavonoids were discussed. It is an accurate and effective method which can be applied for the constituent identification of Platycladi Cacumen.
authors: Nanjing University of Chinese Medicine, Jiangsu Key Laboratory for Traditional Chinese Medicine Formulae Research, Nanjing 210046, China. shanmingqiu@163.com
authors: Mingqiu
authors: M
authors: Shan
authors: Wen
authors: W
authors: Qian
authors: Jing
authors: J
authors: Gao
authors: Yumei
authors: Y
authors: Chi
authors: Li
authors: L
authors: Zhang
authors: Anwei
authors: A
authors: Ding
mesh_terms: D002853:Chromatography, Liquid / Q000379:methods*; D029779:Cupressaceae / Q000737:chemistry*; D005419:Flavonoids / Q000737:chemistry*; D013058:Mass Spectrometry / Q000379:methods*; D010936:Plant Extracts / Q000737:chemistry*
chemical_list: D005419:Flavonoids; D010936:Plant Extracts