title: A case of hyperammonaemic encephalopathy due to valproic acid.
abstract: A patient with valproic acid induced hyperammonaemic encephalopathy is presented. During chronic treatment with valproic acid this patient developed a potentially life-threatening encephalopathy without signs of liver failure. After discontinuing the valproic acid the patient recovered completely. In the case of a patient presenting with hyperammonaemic encephalopathy, the possibility of the use of valproic acid should not be overlooked.
authors: Department of Internal Medicine, Sint Lucas Andreas Hospital, Amsterdam, The Netherlands. meikeprins@hotmail.com
authors: M C
authors: MC
authors: Prins
authors: J J
authors: JJ
authors: van Meijel
mesh_terms: D000927:Anticonvulsants / Q000009:adverse effects* / Q000627:therapeutic use; D004827:Epilepsy / Q000188:drug therapy; D006801:Humans; D022124:Hyperammonemia / Q000139:chemically induced*; D008297:Male; D008875:Middle Aged; D020258:Neurotoxicity Syndromes / Q000209:etiology*; D014635:Valproic Acid / Q000009:adverse effects* / Q000627:therapeutic use
chemical_list: D000927:Anticonvulsants; D014635:Valproic Acid