title: [Severe amblyopia - literature review].
abstract: OBJECTIVE
  The aim of this study was to characterise the visual acuity prognosis in the therapy for severe amblyopia.
  
  
  METHODS
  Literature review on the basis of studies in PubMed was undertaken.
  
  
  RESULTS
  The studies investigating severe amblyopia due to anisometropia and/or strabismus are unanimous in their finding that the early onset of therapy leads to better results for visual acuity. In children under the age of seven years a visual acuity of at least 0.4 (logMAR 0.4); that is, the ability to read, is achieved. At the beginning of therapy, even a partial occlusion with a limited number of hours already shows an improvement in visual acuity. Poor visual acuity at the end of therapy worsens the long-term prognosis. Anisometropia has a poorer visual acuity prognosis than anisohyperopia. Recent studies investigating the possibility of still better visual acuity, and therefore less recurrence of amblyopia and better long-term prognosis, following long-term occlusion therapy are lacking.
  
  
  CONCLUSIONS
  Screening and early and long-term therapy are necessary in order to reduce the prevalence of severe amblyopia.
authors: Augenklinik, Universitätsklinikum Erlangen, Erlangen. gabriele.gusek-schneider@ukerlangen.de
authors: G C
authors: GC
authors: Gusek-Schneider
mesh_terms: D000293:Adolescent; D000367:Age Factors; D000550:Amblyopia / Q000628:therapy*; D015875:Anisocoria / Q000628:therapy; D002648:Child; D002675:Child, Preschool; D015897:Comorbidity; D005403:Fixation, Ocular; D006801:Humans; D008137:Longitudinal Studies; D009216:Myopia / Q000628:therapy; D011379:Prognosis; D012030:Refractive Errors / Q000628:therapy; D012683:Sensory Deprivation; D013285:Strabismus / Q000628:therapy; D016896:Treatment Outcome; D014792:Visual Acuity