title: Membrane trafficking: decoding vesicle identity with contrasting chemistries.
abstract: Proteins involved in membrane traffic must distinguish between different classes of vesicles. New work now shows that α-synuclein and ALPS motifs represent two extreme types of amphipathic helix that are tuned to detect both the curvature of transport vesicles as well as their bulk lipid content.
authors: Department of Biochemistry and Huntsman Cancer Institute, University of Utah, School of Medicine, Salt Lake City, UT 84112, USA. frost@biochem.utah.edu
authors: Adam
authors: A
authors: Frost
mesh_terms: D020816:Amino Acid Motifs; D001665:Binding Sites; D022162:Cytoplasmic Vesicles / Q000737:chemistry / Q000378:metabolism*; D006056:Golgi Apparatus / Q000378:metabolism; D057927:Hydrophobic and Hydrophilic Interactions; D008563:Membrane Lipids / Q000378:metabolism*; D012441:Saccharomyces cerevisiae / Q000166:cytology* / Q000378:metabolism*; D022142:Secretory Vesicles / Q000378:metabolism; D051844:alpha-Synuclein / Q000378:metabolism*
chemical_list: D008563:Membrane Lipids; D051844:alpha-Synuclein