title: Discovery and genomic characterization of a novel ovine partetravirus and a new genotype of bovine partetravirus.
abstract: Partetravirus is a recently described group of animal parvoviruses which include the human partetravirus, bovine partetravirus and porcine partetravirus (previously known as human parvovirus 4, bovine hokovirus and porcine hokovirus respectively). In this report, we describe the discovery and genomic characterization of partetraviruses in bovine and ovine samples from China. These partetraviruses were detected by PCR in 1.8% of bovine liver samples, 66.7% of ovine liver samples and 71.4% of ovine spleen samples. One of the bovine partetraviruses detected in the present samples is phylogenetically distinct from previously reported bovine partetraviruses and likely represents a novel genotype. The ovine partetravirus is a novel partetravirus and phylogenetically most related to the bovine partetraviruses. The genome organization is conserved amongst these viruses, including the presence of a putative transmembrane protein encoded by an overlapping reading frame in ORF2. Results from the present study provide further support to the classification of partetraviruses as a separate genus in Parvovirinae.
authors: Department of Microbiology, The University of Hong Kong, Hong Kong, China.
authors: Herman
authors: H
authors: Tse
authors: Hoi-Wah
authors: HW
authors: Tsoi
authors: Jade L L
authors: JL
authors: Teng
authors: Xin-Chun
authors: XC
authors: Chen
authors: Haiying
authors: H
authors: Liu
authors: Boping
authors: B
authors: Zhou
authors: Bo-Jian
authors: BJ
authors: Zheng
authors: Patrick C Y
authors: PC
authors: Woo
authors: Susanna K P
authors: SK
authors: Lau
authors: Kwok-Yung
authors: KY
authors: Yuen
mesh_terms: D000818:Animals; D002417:Cattle / Q000821:virology*; D004279:DNA, Viral / Q000235:genetics; D016679:Genome, Viral / Q000235:genetics; D023281:Genomics; D005838:Genotype; D006801:Humans; D017992:Parvovirus / Q000235:genetics* / Q000302:isolation & purification*; D010802:Phylogeny; D016133:Polymerase Chain Reaction; D017422:Sequence Analysis, DNA; D012756:Sheep / Q000821:virology*
chemical_list: D004279:DNA, Viral