title: Automatic extraction of 3D dynamic left ventricle model from 2D rotational angiocardiogram.
abstract: In this paper, we propose an automatic method to directly extract 3D dynamic left ventricle (LV) model from sparse 2D rotational angiocardiogram (each cardiac phase contains only five projections). The extracted dynamic model provides quantitative cardiac function for analysis. The overlay of the model onto 2D real-time fluoroscopic images provides valuable visual guidance during cardiac intervention. Though containing severe cardiac motion artifacts, an ungated CT reconstruction is used in our approach to extract a rough static LV model. The initialized LV model is projected onto each 2D projection image. The silhouette of the projected mesh is deformed to match the boundary of LV blood pool. The deformation vectors of the silhouette are back-projected to 3D space and used as anchor points for thin plate spline (TPS) interpolation of other mesh points. The proposed method is validated on 12 synthesized datasets. The extracted 3D LV meshes match the ground truth quite well with a mean point-to-mesh error of 0.51 +/- 0.11 mm. The preliminary experiments on two real datasets (included a patient and a pig) show promising results too.
authors: Image Analytics and Informatics, Siemens Corporate Research, Princeton, NJ, USA.
authors: Mingqing
authors: M
authors: Chen
authors: Yefeng
authors: Y
authors: Zheng
authors: Kerstin
authors: K
authors: Mueller
authors: Christopher
authors: C
authors: Rohkohl
authors: Guenter
authors: G
authors: Lauritsch
authors: Jan
authors: J
authors: Boese
authors: Gareth
authors: G
authors: Funka-Le
authors: Joachim
authors: J
authors: Hornegger
authors: Dorin
authors: D
authors: Comaniciu
mesh_terms: D000465:Algorithms; D000792:Angiography / Q000379:methods*; D000818:Animals; D001331:Automation; D003952:Diagnostic Imaging / Q000379:methods; D004562:Electrocardiography / Q000379:methods*; D005471:Fluoroscopy / Q000379:methods; D006352:Heart Ventricles / Q000473:pathology; D006801:Humans; D021621:Imaging, Three-Dimensional / Q000379:methods*; D015233:Models, Statistical; D009038:Motion; D010363:Pattern Recognition, Automated; D015203:Reproducibility of Results; D013552:Swine; D014057:Tomography, X-Ray Computed / Q000379:methods