title: [The study on significance of detecting the hepatitis B virus large proteins in public health physical examination].
abstract: OBJECTIVE
  It was to explore the application of the hepatitis B virus large proteins (HBV-LP) in public health physical examination through clinical testing of HBV-LP in Catering practitioners, students and soldiers of New requisition etc.
  
  
  METHODS
  709 samples of HBV infection people were collected in public health physical examination and all collected samples were detected. ELISA was used to detect HBV serum markers (HBV-M) and HBV-LP. Real-time PCR was applied to detect quantity of HBV DNA.
  
  
  RESULTS
  (1) The detectable results of HBV-LP and HBV DNA were no statistical significance in 709 samples. (2) The detectable results of HBV-LP and HBV DNA were also no statistical significance in different models of HBV infection patients. The values of chi2 and P were respectively 2.67, 0.60, 0.00 and 0.10, 0.44, 1.00. S/A of HBV-LP and the copies of HBV-DNA had a positive relationship (r = 0.959, P < 0.05).
  
  
  CONCLUSIONS
  HBV-LP could reflect the level of hepatitis B virus replication and be used to judge the level of hepatitis B virus replication in people of public health physical examination. HBV-LP may be worth using widely in physical examination.
authors: Shaoxing Center for Disease Control and Prevention, Shaoxing 312071, China.
authors: Guo-Shao
authors: GS
authors: Pan
authors: Xing-Xiang
authors: XX
authors: Jiang
authors: Jin-Kun
authors: JK
authors: Chen
authors: Dong-Qing
authors: DQ
authors: Cao
authors: Dan-Yan
authors: DY
authors: Zhao
authors: Ming-Zhi
authors: MZ
authors: Jian
authors: Yi
authors: Y
authors: Zhang
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D005260:Female; D006515:Hepatitis B virus / Q000235:genetics / Q000378:metabolism*; D006801:Humans; D008111:Liver Function Tests; D008297:Male; D008875:Middle Aged; D011634:Public Health; D014764:Viral Proteins / Q000235:genetics / Q000378:metabolism*; D055815:Young Adult
chemical_list: D014764:Viral Proteins