title: High-frequency oscillations and other electrophysiological biomarkers of epilepsy: clinical studies.
abstract: Accurate localization of epileptogenic brain is critical for successful epilepsy surgery. Recent research using wide bandwidth intracranial EEG has demonstrated that interictal high-frequency oscillations are preferentially localized to the brain region generating spontaneous seizures, and are a potential biomarker of epileptogenic brain. The existence of an interictal, electrophysiological biomarker of epileptogenic brain has the potential to significantly advance epilepsy surgery by improving outcomes through improved localization and potentially eliminating the reliance on chronic intracranial EEG monitoring.
authors: Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA. worrell.gregory@mayo.edu
authors: Greg
authors: G
authors: Worrell
authors: Jean
authors: J
authors: Gotman
mesh_terms: D015415:Biomarkers / Q000737:chemistry*; D001921:Brain / Q000503:physiopathology; D004569:Electroencephalography; D004827:Epilepsy / Q000503:physiopathology* / Q000601:surgery; D006624:Hippocampus / Q000503:physiopathology; D006801:Humans; D012640:Seizures / Q000503:physiopathology / Q000601:surgery
chemical_list: D015415:Biomarkers