title: [Expression of neural salient serine-/arginine-rich protein 1 (NSSR1) in colorectal cancer].
abstract: OBJECTIVE
  To investigate the expression of neural salient serine/arginine-rich protein 1 (NSSR1) in colorectal cancer.
  
  
  METHODS
  RT-PCR, Western blot and immunohistochemical staining were used to detect the expression of NSSR1 mRNA and protein in different mouse tissues and human colorectal cancer, respectively.
  
  
  RESULTS
  NSSR1 mRNA was expressed in mouse cerebrum, cerebellum, heart, liver, intestine, kidney and lung tissue, but NSSR1 protein was only expressed in neural tissues. In normal human intestinal mucosa, NSSR1 was expressed in the colorectal epithelial cells. In colorectal cancer, NSSR1 was highly expressed in the nucleus of tumor cells.
  
  
  CONCLUSIONS
  The extensive expression of NSSR1 in colorectal cancer cells may hint it's roles in the biological function of colorectal cancer.
authors: School of Medicine and Life Science, Zhejiang University City College, Hangzhou, China.
authors: Wei
authors: W
authors: Zhang
authors: Quan
authors: Q
authors: Shen
authors: Jia-xi
authors: JX
authors: Shen
mesh_terms: D000818:Animals; D018797:Cell Cycle Proteins / Q000235:genetics / Q000378:metabolism*; D003106:Colon / Q000378:metabolism; D015179:Colorectal Neoplasms / Q000378:metabolism*; D006801:Humans; D051379:Mice; D009363:Neoplasm Proteins / Q000235:genetics / Q000378:metabolism*; D012333:RNA, Messenger / Q000235:genetics; D016601:RNA-Binding Proteins / Q000235:genetics / Q000378:metabolism*; D012007:Rectum / Q000378:metabolism; D012097:Repressor Proteins / Q000235:genetics / Q000378:metabolism*; D000068103:Serine-Arginine Splicing Factors
chemical_list: D018797:Cell Cycle Proteins; C485446:Fusip1 protein, mouse; D009363:Neoplasm Proteins; D012333:RNA, Messenger; D016601:RNA-Binding Proteins; D012097:Repressor Proteins; C115188:SRSF10 protein, human; D000068103:Serine-Arginine Splicing Factors