title: Ten years of HIV testing with fourth generation assays: the Amsterdam experience.
abstract: Serological HIV assays combining detection of HIV antigen and antibodies are referred to as fourth generation assays. Fourth generation assays were implemented in Europe for routine patient testing about 10 years ago. The Academic Medical Center is one of the main HIV treatment centers in the Netherlands and has now 10 years experience with fourth generation testing, which is summarized here.
authors: Department of Medical Microbiology, Laboratory of Clinical Virology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
authors: Suzanne
authors: S
authors: Jurriaans
authors: Nicole K T
authors: NK
authors: Back
authors: Katja C
authors: KC
authors: Wolthers
mesh_terms: D000465:Algorithms; D015153:Blotting, Western; D015483:HIV Antibodies / Q000032:analysis* / Q000276:immunology; D015488:HIV Antigens / Q000032:analysis* / Q000276:immunology; D015658:HIV Infections / Q000175:diagnosis* / Q000453:epidemiology / Q000276:immunology / Q000821:virology; D015497:HIV-1 / Q000235:genetics / Q000276:immunology / Q000472:pathogenicity; D015498:HIV-2 / Q000235:genetics / Q000276:immunology / Q000472:pathogenicity; D006801:Humans; D007118:Immunoassay / Q000379:methods; D008403:Mass Screening / Q000379:methods; D009426:Netherlands / Q000453:epidemiology; D012367:RNA, Viral / Q000032:analysis; D012698:Serologic Tests / Q000379:methods; D013997:Time Factors; D019562:Viral Load
chemical_list: D015483:HIV Antibodies; D015488:HIV Antigens; D012367:RNA, Viral