title: Histological examination of the intestine from dogs and cats with intussusception.
abstract: OBJECTIVE
  To review the histological findings in the intestine from dogs and cats with intussusception.
  
  
  METHODS
  Medical records and histopathology reports of dogs and cats with intussusception were reviewed retrospectively.
  
  
  RESULTS
  Fourty-nine animals (31 dogs and 18 cats) were identified for inclusion. Tissues examined com-prised the intussusception alone in 29 animals (16 dogs and 13 cats), and the intussusception with additional intestinal biopsies in 20 animals (15 dogs and 5 cats). Twenty-eight of 49 (57·1%) animals, comprising 19 of 31 (61·3%) dogs and 9 of 18 cats (50%) had abnormalities detected on histological examination of tissue. Eleven of 29 (46·9%) cases where only the intussusception was submitted achieved a histological diagnosis, compared to 17 of 20 (85%) where additional biopsies were submitted (P=0·003). Cats (median age 36 months, range 2 to 174) were significantly older than dogs (median age 7·5 months, range 1 to 125 months, P=0·010) and were significantly more likely to have underlying neoplasia (5 of 9; 55·6%) compared to dogs who were more likely to have inflammatory causes (17 of 19; 89·5%, P=0·020). There was no association between histological diagnosis and location of the intussusception (P=1·000).
  
  
  CONCLUSIONS
  Histological abnormalities were detected in more than half of the animals. Diagnosis of intestinal disease in animals with intussusception may be improved by submission of additional biopsy samples. Cats with intussusception are more likely to be older and have underlying neoplasia than dogs which are more likely to have inflammatory disease.
authors: Department of Veterinary Clinical Sciences, The Royal Veterinary College, Hawkshead Lane, North Mymms, Hatfield, Hertfordshire AL9 7TA.
authors: A S
authors: AS
authors: Levien
authors: S J
authors: SJ
authors: Baines
mesh_terms: D000367:Age Factors; D000818:Animals; D001706:Biopsy / Q000662:veterinary; D002371:Cat Diseases / Q000209:etiology / Q000473:pathology*; D002415:Cats; D004283:Dog Diseases / Q000209:etiology / Q000473:pathology*; D004285:Dogs; D005260:Female; D007249:Inflammation / Q000150:complications / Q000662:veterinary; D007414:Intestinal Neoplasms / Q000150:complications / Q000662:veterinary; D007443:Intussusception / Q000209:etiology / Q000473:pathology / Q000662:veterinary*; D008297:Male; D012189:Retrospective Studies; D013045:Species Specificity