title: Coronary artery angiographic changes in veterans poisoned by mustard gas.
abstract: OBJECTIVE
  We aimed to identify coronary artery involvement in mustard gas-poisoned patients.
  
  
  METHODS
  We conducted a case-control study on 40 mustard gas-poisoned patients who underwent coronary artery angiography due to cardiac pain. The study was performed during a 3-year interval on patients who were referred to three main hospitals of Mashhad, Iran. The nonexposed control group consisted of 40 normal individuals who had undergone angiography for the same reasons. The primary outcome measurement was coronary artery involvement and its location. Data were collected through studying the angiography films.
  
  
  RESULTS
  Among the 40 poisoned patients studied, 15 (37.5%) had coronary artery ectasia, mainly in the left anterior descending artery, but 25 (62.5%) did not. The same values were 2 (5%) and 38 (95%) in the nonexposed group, respectively, which was significantly different compared to the exposed group (p = 0.001). The odds ratio was 11.40.
  
  
  CONCLUSIONS
  The prevalence of coronary artery ectasia in mustard gas-poisoned patients was 7.5 times more than in nonexposed controls. Considering the proposed odds ratio, the occurrence of coronary artery ectasia is around 11.4 times greater in mustard gas-poisoned veterans. This is the first study to suggest a strong correlation between mustard gas poisoning and coronary artery ectasia.
authors: Department of Interventional Cardiology, Imam Reza Hospital, Mashhad, Iran.
authors: Mahmoud M
authors: MM
authors: Shabestari
authors: Farahzad
authors: F
authors: Jabbari
authors: Behnaz
authors: B
authors: Gohari
authors: Nasrin
authors: N
authors: Moazen
authors: Hoda
authors: H
authors: Azizi
authors: Toktam
authors: T
authors: Moghiman
authors: Saeed
authors: S
authors: Ibrahimzadeh
authors: Amir
authors: A
authors: Amirabadi
mesh_terms: D000368:Aged; D016022:Case-Control Studies; D002619:Chemical Warfare Agents / Q000506:poisoning*; D003323:Coronary Aneurysm / Q000139:chemically induced / Q000000981:diagnostic imaging / Q000473:pathology; D017023:Coronary Angiography; D003324:Coronary Artery Disease / Q000139:chemically induced* / Q000000981:diagnostic imaging / Q000473:pathology; D004108:Dilatation, Pathologic / Q000139:chemically induced / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D007492:Iran; D008297:Male; D008875:Middle Aged; D009151:Mustard Gas / Q000506:poisoning*; D014728:Veterans
chemical_list: D002619:Chemical Warfare Agents; D009151:Mustard Gas