title: Evaluation of the interaction between endodontic sealers and dentin treated with different irrigant solutions.
abstract: BACKGROUND
  Dentin surface treatment with different substances might cause alterations in chemical and structural compositions of the human dentin. The aim of this study was to investigate the wettability of endodontic sealers in contact with dentin treated with 5.25% sodium hypochlorite (NaOCl) and 2% chlorhexidine (CHX) in the presence or absence of smear layer.
  
  
  METHODS
  Thirty-six dentin slices were used. They were irrigated with NaOCl and washed with distilled water (DW) to simulate irrigation during chemomechanical preparation. After this procedure, the samples were divided into 6 groups: group 1, DW (control); group 2, NaOCl + DW; group 3, CHX + DW; group 4, ethylenediaminetetraacetic acid (EDTA) + DW; group 5, EDTA + DW + NaOCl + DW; group 6, EDTA + DW + CHX + DW. The Ramé-Hart goniometer was used to measure the contact angle between the dentin surfaces and the AH Plus and Real Seal SE sealers. Data were statistically analyzed.
  
  
  RESULTS
  With regard to the contact angle between AH Plus and treated surfaces, the values of contact angle were lower when CHX was used, regardless of the presence or absence of smear layer. When Real Seal SE was evaluated, in the absence of smear layer, CHX presented lower values of contact angle. In the presence of smear layer, the use of NaOCl and CHX did not favor the spread of the sealer.
  
  
  CONCLUSIONS
  The present study has revealed that smear layer removal and final flush with CHX favor the wettability of AH Plus and Real Seal SE sealers.
authors: Department of Metallurgic and Materials Engineering, Federal University of Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil.
authors: Danielle Ferreira
authors: DF
authors: de Assis
authors: Maíra do
authors: Md
authors: Prado
authors: Renata A
authors: RA
authors: Simão
mesh_terms: D002710:Chlorhexidine / Q000494:pharmacology; D003188:Composite Resins / Q000494:pharmacology; D003786:Dental Pulp Cavity; D003804:Dentin / Q000187:drug effects*; D003806:Dentin Permeability / Q000187:drug effects; D003808:Dentin Solubility / Q000187:drug effects; D004347:Drug Interactions; D004492:Edetic Acid / Q000494:pharmacology; D004853:Epoxy Resins / Q000494:pharmacology; D006801:Humans; D012387:Root Canal Filling Materials / Q000494:pharmacology*; D012388:Root Canal Irrigants / Q000494:pharmacology*; D016369:Smear Layer; D012973:Sodium Hypochlorite / Q000494:pharmacology; D018709:Statistics, Nonparametric; D014867:Water; D017155:Wettability
chemical_list: D003188:Composite Resins; D004853:Epoxy Resins; C511498:Real Seal composite resin; D012387:Root Canal Filling Materials; D012388:Root Canal Irrigants; C534916:epoxy resin-based root canal sealer; D014867:Water; D004492:Edetic Acid; D012973:Sodium Hypochlorite; D002710:Chlorhexidine