title: A stochastic model of autocatalytic reaction networks.
abstract: Autocatalytic cycles are rather widespread in nature and in several theoretical models of catalytic reaction networks their emergence is hypothesized to be inevitable when the network is or becomes sufficiently complex. Nevertheless, the emergence of autocatalytic cycles has been never observed in wet laboratory experiments. Here, we present a novel model of catalytic reaction networks with the explicit goal of filling the gap between theoretical predictions and experimental findings. The model is based on previous study of Kauffman, with new features in the introduction of a stochastic algorithm to describe the dynamics and in the possibility to increase the number of elements and reactions according to the dynamical evolution of the system. Furthermore, the introduction of a temporal threshold allows the detection of cycles even in our context of a stochastic model with asynchronous update. In this study, we describe the model and present results concerning the effect on the overall dynamics of varying (a) the average residence time of the elements in the reactor, (b) both the composition of the firing disk and the concentration of the molecules belonging to it, (c) the composition of the incoming flux.
authors: European Centre for Living Technology, Calle del Clero 2940, 30124 Venice, Italy. alessandro.filisetti@ecltech.org
authors: Alessandro
authors: A
authors: Filisetti
authors: Alex
authors: A
authors: Graudenzi
authors: Roberto
authors: R
authors: Serra
authors: Marco
authors: M
authors: Villani
authors: Rudolf M
authors: RM
authors: Füchslin
authors: Norman
authors: N
authors: Packard
authors: Stuart A
authors: SA
authors: Kauffman
authors: Irene
authors: I
authors: Poli
mesh_terms: D002384:Catalysis; D003198:Computer Simulation; D008954:Models, Biological; D011108:Polymers / Q000737:chemistry*; D013269:Stochastic Processes
chemical_list: D011108:Polymers