title: [Study on the estrogen derivative marked by CdTe quantum dots].
abstract: Water-soluble CdTe quantum dots (QDs) stabilized by thioglycolic acid (TGA) with high quantum yield were synthesized. And the small biomolecule 17beta-amino-estradiol was marked successfully by CdTe QDs. The analysis of UV-Vis spectroscopy, fluorescence spectroscopy, infrared spectroscopy and inverted microscope photographs showed that the surface carboxyl of CdTe quantum dots conjugated with the amino of 17beta-amino-estradiol through the activation of N-hydroxysuccinimide. 17beta-amino-estradiol marked by CdTe QDs successfully provided an experimental basis for new drug screening model.
authors: Department of Analytical Chemistry, China Pharmaceutical University, Nanjing 210009, China. wyzhong@cpu.edu.cn
authors: Wen-Ying
authors: WY
authors: Zhong
authors: Cui
authors: C
authors: Zhang
authors: Guo-Feng
authors: GF
authors: Xu
authors: Ming
authors: M
authors: Yan
authors: Dan-Ke
authors: DK
authors: Xu
mesh_terms: D019187:Cadmium Compounds; D004967:Estrogens / Q000737:chemistry*; D045663:Quantum Dots; D013050:Spectrometry, Fluorescence; D013388:Succinimides; D013691:Tellurium; D013864:Thioglycolates; D014867:Water
chemical_list: D019187:Cadmium Compounds; D004967:Estrogens; D013388:Succinimides; D013864:Thioglycolates; D014867:Water; C017487:2-mercaptoacetate; C001426:N-hydroxysuccinimide; D013691:Tellurium