title: Hyperbranched polymers for molecular imaging: designing polymers for parahydrogen induced polarisation (PHIP).
abstract: The first hyperpolarisation of polymers using parahydrogen induced polarisation (PHIP) is reported by hydrogenation of terminal alkyne groups in a biocompatible hyperbranched polymer. Signal enhancements of 1500-fold could be obtained depending on the structure of the polymer, thus opening new potential avenues for polymeric molecular imaging.
authors: Max Planck Institute for Polymer Research, Ackermannweg 10, 55128 Mainz, Germany. muenne@mpip-mainz.mpg.de
authors: Kerstin
authors: K
authors: Münnemann
authors: Michael
authors: M
authors: Kölzer
authors: Idriss
authors: I
authors: Blakey
authors: Andrew K
authors: AK
authors: Whittaker
authors: Kristofer J
authors: KJ
authors: Thurecht
mesh_terms: D000480:Alkynes / Q000737:chemistry; D006865:Hydrogenation; D057054:Molecular Imaging; D015394:Molecular Structure; D011108:Polymers / Q000138:chemical synthesis / Q000737:chemistry*
chemical_list: D000480:Alkynes; D011108:Polymers