title: A plug and play polymeric template driven by supramolecular interactions.
abstract: A new "plug and play" polymeric template with the driving force of host-guest interaction between β-CD and naphthalene-modified functional groups was designed and studied. Multiple functional groups can be loaded into the template directly and conveniently. Importantly, the "plug and play" effect of the polymeric template is reversible and the functional groups could be removed from the polymeric template conveniently by adding AD-HCl. The studies on the cell viability and phagocytosis proved that the loading and unloading process of this template could be realized in vitro.
authors: Key Laboratory of Biomedical Polymers of Ministry of Education and Department of Chemistry, Wuhan University, Wuhan 430072, People's Republic of China.
authors: Wang
authors: W
authors: Xiao
authors: Wei-Hai
authors: WH
authors: Chen
authors: Cao
authors: C
authors: Li
authors: Jin-Xiao
authors: JX
authors: Chen
authors: Xian-Zheng
authors: XZ
authors: Zhang
authors: Ren-Xi
authors: RX
authors: Zhuo
mesh_terms: D000818:Animals; D019556:COS Cells; D002166:Camptothecin / Q000494:pharmacology; D016923:Cell Death / Q000187:drug effects; D002522:Chlorocebus aethiops; D005029:Ethylenediamines / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D006367:HeLa Cells; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D018613:Microscopy, Confocal; D009280:Naphthaleneacetic Acids / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D009842:Oligopeptides / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D010455:Peptides / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D011108:Polymers / Q000138:chemical synthesis* / Q000737:chemistry* / Q000494:pharmacology; D013050:Spectrometry, Fluorescence; D047392:beta-Cyclodextrins / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology
chemical_list: D005029:Ethylenediamines; D009280:Naphthaleneacetic Acids; D009842:Oligopeptides; D010455:Peptides; D011108:Polymers; D047392:beta-Cyclodextrins; C017645:polyaspartate; C020424:2-naphthylacetic acid; C047981:arginyl-glycyl-aspartic acid; D002166:Camptothecin