title: [C-reactive protein as an inflammatory marker in monitoring therapy effectiveness of acute odontogenic infections].
abstract: BACKGROUND
  Clinical presentation of acute odontogenic infections may vary, while adequate evaluation of its severity is of great importance for determination of appropriate and effective therapy.
  
  
  OBJECTIVE
  The aim of the present study was to monitor changes of C-reactive protein (CRP) levels, to correlate its values with symptoms of different acute odontogenic infections (AOI), and to monitor the effectiveness of the applied therapy.
  
  
  METHODS
  Fifty-four patients with AOI were included in the study. Eighteen patients with good drainage and normal body temperature were treated only by surgical incision without using antibiotics. Twenty-two patients with poor drainage after incision and normal body temperature were treated by surgical incision and antibiotics. Fourteen patients with elevated body temperature were treated by incision and antibiotics, irrespective of the quality of the drainage. CRP levels were measured on admission, on the 3rd and 7th day after therapy initiation.
  
  
  RESULTS
  On admission CRP levels were higher in AOI with elevated body temperature compared to poorly and well-drained AOI. There were no differences in CRP levels between well and poorly drained AOI on admission. On the 3rd day, a decline in the CRP levels was evident in all three groups of patients, and there was no difference among the groups. On the 7th day, the CRP levels normalized in all groups.
  
  
  CONCLUSIONS
  CRP levels correlate well with the severity and resolution of AOI and could be used as a reliable parameter in monitoring the effectiveness of AOI therapy.
authors: Radojica
authors: R
authors: Dražić
authors: Milan
authors: M
authors: Jurišić
authors: Aleksa
authors: A
authors: Marković
authors: Snežana
authors: S
authors: Colić
authors: Bojan
authors: B
authors: Gačić
authors: Ljiljana
authors: L
authors: Stojčev-Stajčić
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015415:Biomarkers / Q000097:blood; D002097:C-Reactive Protein / Q000032:analysis*; D002648:Child; D005260:Female; D005491:Focal Infection, Dental / Q000175:diagnosis / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D055815:Young Adult
chemical_list: D015415:Biomarkers; D002097:C-Reactive Protein