title: Late-onset prosthetic valve endocarditis caused by Mycoplasma hominis, diagnosed using broad-range bacterial PCR.
abstract: We report what is believed to be the first case of late-onset prosthetic valve endocarditis caused by Mycoplasma hominis in a case of blood culture-negative endocarditis. The objective of this report is to emphasize the use of a broad-range PCR technique for bacterial 16S rRNA genes in identifying the causative pathogen, thus enabling targeted antimicrobial treatment.
authors: Department of Cardiology, Leeds General Infirmary, Great George Street, Leeds LS1 3EX, UK.
authors: H A
authors: HA
authors: Jamil
authors: Department of Microbiology, Leeds General Infirmary, Great George Street, Leeds LS1 3EX, UK.
authors: J A T
authors: JAT
authors: Sandoe
authors: Department of Microbiology, Leeds General Infirmary, Great George Street, Leeds LS1 3EX, UK.
authors: D
authors: D
authors: Gascoyne-Binzi
authors: Centre for Infections, Health Protection Agency, 61 Colindale Avenue, London NW9 5HT, UK.
authors: V J
authors: VJ
authors: Chalker
authors: Department of Cardiology, Leeds General Infirmary, Great George Street, Leeds LS1 3EX, UK.
authors: A D
authors: AD
authors: Simms
authors: Department of Cardiac Surgery, Leeds General Infirmary, Great George Street, Leeds LS1 3EX, UK.
authors: C M
authors: CM
authors: Munsch
authors: Department of Cardiology, Leeds General Infirmary, Great George Street, Leeds LS1 3EX, UK.
authors: M W
authors: MW
authors: Baig
mesh_terms: D000328:Adult; D004269:DNA, Bacterial / Q000737:chemistry / Q000235:genetics; D004275:DNA, Ribosomal / Q000737:chemistry / Q000235:genetics; D004697:Endocarditis, Bacterial / Q000175:diagnosis* / Q000382:microbiology / Q000473:pathology; D006801:Humans; D008297:Male; D009175:Mycoplasma Infections / Q000175:diagnosis* / Q000382:microbiology / Q000473:pathology; D019535:Mycoplasma hominis / Q000235:genetics / Q000302:isolation & purification*; D016133:Polymerase Chain Reaction; D016459:Prosthesis-Related Infections / Q000175:diagnosis* / Q000382:microbiology / Q000473:pathology; D012336:RNA, Ribosomal, 16S / Q000235:genetics; D017422:Sequence Analysis, DNA
chemical_list: D004269:DNA, Bacterial; D004275:DNA, Ribosomal; D012336:RNA, Ribosomal, 16S