title: Concise formal synthesis of (+)-neopeltolide.
abstract: A concise formal synthesis of (+)-neopeltolide (1) has been accomplished. The synthesis demonstrated high atom efficiency employing only one step of functional group protection. Key steps involved iridium-catalyzed double asymmetric carbonyl allylation, palladium-catalyzed intramolecular alkoxycarbonylation, ruthenium-catalyzed olefin isomerization, and ring-closing metathesis.
authors: State Key Laboratory of Applied Organic Chemistry, Department of Chemistry, Lanzhou University, Lanzhou 730000, People's Republic of China.
authors: Zhen
authors: Z
authors: Yang
authors: Bingbin
authors: B
authors: Zhang
authors: Gaoyuan
authors: G
authors: Zhao
authors: Juan
authors: J
authors: Yang
authors: Xingang
authors: X
authors: Xie
authors: Xuegong
authors: X
authors: She
mesh_terms: D018942:Macrolides / Q000138:chemical synthesis*; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D018942:Macrolides; C519136:neopeltolide