title: Bacteriophage assembly.
abstract: Bacteriophages have been a model system to study assembly processes for over half a century. Formation of infectious phage particles involves specific protein-protein and protein-nucleic acid interactions, as well as large conformational changes of assembly precursors. The sequence and molecular mechanisms of phage assembly have been elucidated by a variety of methods. Differences and similarities of assembly processes in several different groups of bacteriophages are discussed in this review. The general principles of phage assembly are applicable to many macromolecular complexes.
authors: Department of Biological Sciences, Purdue University, West Lafayette, IN 47907, USA.
authors: Anastasia A
authors: AA
authors: Aksyuk
authors: Department of Biological Sciences, Purdue University, West Lafayette, IN 47907, USA.
authors: Michael G
authors: MG
authors: Rossmann
mesh_terms: D001435:Bacteriophages / Q000235:genetics / Q000502:physiology*; D014764:Viral Proteins / Q000235:genetics / Q000378:metabolism; D019065:Virus Assembly
chemical_list: D014764:Viral Proteins