title: A dysphagia study in patients with sporadic inclusion body myositis (s-IBM).
abstract: The nature of the swallowing impairment in patients with sporadic inclusion body myositis (s-IBM) has not been well characterized. In this study, we examined ten consecutive s-IBM patients using videofluoroscopy (VF) and computed pharyngoesophageal manometry (CPM). The patients were divided into two groups: patients with complaint and without complaint of dysphagia. VF results indicated pharyngeal muscle propulsion (PP) at the hypopharyngeal and upper esophagus sphincter (UES) in all s-IBM patients. Patients without complaint of dysphagia showed a mild degree of PP, whereas a severe form of PP was observed in patients with complaint of dysphagia. CPM revealed that negative pressure during UES opening was not observed in the s-IBM patients with complaint of dysphagia. Incomplete opening and PP at the UES were observed in all s-IBM patients. These results indicate that the dysphagic processes occur subclinically in s-IBM patients who may not report swallowing impairments.
authors: Department of Neurology, Wakayama Medical University, 840-1 Kimii-dera, Wakayama 641-8510, Japan. kemurata@wakayama-med.ac.jp
authors: Ken-Ya
authors: KY
authors: Murata
authors: Ken
authors: K
authors: Kouda
authors: Fumihiro
authors: F
authors: Tajima
authors: Tomoyoshi
authors: T
authors: Kondo
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003680:Deglutition Disorders / Q000175:diagnosis* / Q000209:etiology*; D005260:Female; D005471:Fluoroscopy / Q000379:methods; D006801:Humans; D008297:Male; D008365:Manometry / Q000379:methods; D008875:Middle Aged; D018979:Myositis, Inclusion Body / Q000150:complications*; D010609:Pharyngeal Muscles / Q000503:physiopathology; D016672:Zenker Diverticulum / Q000473:pathology