title: Synaptic ribbons: machines for priming vesicle release?
abstract: Synaptic ribbons are specialized organelles that hold vesicles close to the active zone of sensory synapses, but their function is mysterious. Acute disruption of the ribbon complex using light has now revealed that it has a role in priming synaptic vesicles for fusion.
authors: MRC Laboratory of Molecular Biology, Cambridge, CB2 0QH, UK.
authors: Ilaria
authors: I
authors: Pelassa
authors: Leon
authors: L
authors: Lagnado
mesh_terms: D000429:Alcohol Oxidoreductases; D000818:Animals; D056970:Co-Repressor Proteins; D004268:DNA-Binding Proteins / Q000378:metabolism / Q000494:pharmacology; D019706:Excitatory Postsynaptic Potentials / Q000502:physiology*; D005089:Exocytosis; D008027:Light / Q000009:adverse effects; D051379:Mice; D008810:Mice, Inbred C57BL; D010455:Peptides / Q000378:metabolism; D010750:Phosphoproteins / Q000378:metabolism / Q000494:pharmacology; D011485:Protein Binding; D012160:Retina / Q000166:cytology*; D051245:Retinal Bipolar Cells / Q000166:cytology*; D013569:Synapses / Q000502:physiology*; D013572:Synaptic Vesicles / Q000502:physiology*
chemical_list: D056970:Co-Repressor Proteins; D004268:DNA-Binding Proteins; D010455:Peptides; D010750:Phosphoproteins; D000429:Alcohol Oxidoreductases; C111341:Ctbp2 protein, mouse