title: [Diagnostic laparoscopy under dual antiplatelet therapy with clopidogrel and aspirin].
abstract: Dual antiplatelet therapy using aspirin and a thienopyridine (e.g. clopidogrel) is known to be essential in patients in whom percutaneous coronary intervention with stent implantation has been performed in order to prevent stent thrombosis and its fatal consequences. On the other hand dual antiplatelet therapy increases the incidence of perioperative bleeding complications. In case of urgent or emergency surgery the risk of perioperative stent thrombosis on the one hand and the perioperative bleeding risk on the other has to be evaluated carefully in order to keep time period without sufficient platelet inhibition as short as possible. The presented case offers a strategy for managing perioperative administration of antiplatelet agents.
authors: Klinik und Poliklinik für Innere Medizin III, Universitätsklinikum Halle (Saale) der Martin-Luther-Universität Halle-Wittenberg, Halle (Saale), Deutschland. alexander.vogt@medizin.uni-halle.de
authors: A
authors: A
authors: Vogt
authors: A
authors: A
authors: Schlitt
authors: M
authors: M
authors: Buerke
authors: F
authors: F
authors: Mannes
authors: H-H
authors: HH
authors: Wolf
authors: K
authors: K
authors: Werdan
authors: A
authors: A
authors: Plehn
mesh_terms: D000368:Aged; D015906:Angioplasty, Balloon, Coronary; D001241:Aspirin / Q000008:administration & dosage / Q000009:adverse effects*; D000077144:Clopidogrel; D003937:Diagnosis, Differential; D057915:Drug Substitution; D004359:Drug Therapy, Combination; D054855:Drug-Eluting Stents; D000077542:Eptifibatide; D005260:Female; D006801:Humans; D010535:Laparoscopy; D009101:Multiple Myeloma / Q000175:diagnosis; D010455:Peptides / Q000008:administration & dosage / Q000009:adverse effects; D010975:Platelet Aggregation Inhibitors / Q000008:administration & dosage / Q000009:adverse effects*; D019106:Postoperative Hemorrhage / Q000139:chemically induced*; D012307:Risk Factors; D013927:Thrombosis / Q000517:prevention & control; D013988:Ticlopidine / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives*
chemical_list: D010455:Peptides; D010975:Platelet Aggregation Inhibitors; D000077144:Clopidogrel; D000077542:Eptifibatide; D013988:Ticlopidine; D001241:Aspirin