title: Role of pretrial systemic opioid requirements, intrathecal trial dose, and non-psychological factors as predictors of outcome for intrathecal pump therapy: one clinician's experience with lumbar postlaminectomy pain.
abstract: OBJECTIVE
  Non-psychological parameters may predict pump success.
  
  
  METHODS
  Review was performed on 35 implants for gender, age, pretrial/trial dose, baseline visual analog scale (VAS), and pain location. One-year outcomes were % change VAS/intrathecal dose and medication change. Spearman coefficients correlated pretrial/trial dose, age, baseline VAS, and % change in VAS/intrathecal dose. Wilcoxon Rank-Sum tests correlated gender/pain location and % change in VAS/intrathecal dose. Pretrial/trial dose, baseline VAS, and medication change was tested using Wilcoxon Rank-Sums. Chi-square was used to correlate medication change with gender/pain location. A two-sample t-test compared age and medication change.
  
  
  RESULTS
  Positive correlation between % change VAS and trial dose was noted. Greater age correlated with lower VAS and % dose change. Marginally significant difference in % dose change by pain location was present with higher doses for leg pain.
  
  
  CONCLUSIONS
  Trial dose, age, and partially pain location are good predictors of pain relief.
authors: Department of Anesthesiology, Henry Ford Hospital, Detroit, MI 48202, USA. dklm1@hfhs.org
authors: David
authors: D
authors: Kim
authors: Alik
authors: A
authors: Saidov
authors: Vijay
authors: V
authors: Mandhare
authors: Adam
authors: A
authors: Shuster
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000701:Analgesics, Opioid / Q000008:administration & dosage* / Q000627:therapeutic use*; D059350:Chronic Pain / Q000188:drug therapy / Q000523:psychology; D002986:Clinical Trials as Topic; D005260:Female; D006801:Humans; D015918:Infusion Pumps, Implantable / Q000523:psychology*; D007278:Injections, Spinal; D017116:Low Back Pain / Q000188:drug therapy* / Q000523:psychology*; D008297:Male; D008875:Middle Aged; D010147:Pain Measurement / Q000523:psychology; D018579:Patient Selection; D012189:Retrospective Studies; D016896:Treatment Outcome
chemical_list: D000701:Analgesics, Opioid