title: Synthetic route to chiral tetrahydroquinoxalines via ring-opening of activated aziridines.
abstract: A highly regio- and stereoselective route for the synthesis of racemic and nonracemic tetrahydroquinoxalines via the S(N)2-type ring-opening of activated aziridines with 2-bromoanilines followed by the Pd-catalyzed intramolecular C-N bond formation is described.
authors: Department of Chemistry, Indian Institute of Technology, Kanpur 208016, India.
authors: Manas K
authors: MK
authors: Ghorai
authors: Ashis K
authors: AK
authors: Sahoo
authors: Sarvesh
authors: S
authors: Kumar
mesh_terms: D001388:Aziridines / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D006865:Hydrogenation; D008958:Models, Molecular; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry; D011810:Quinoxalines / Q000138:chemical synthesis*; D013237:Stereoisomerism
chemical_list: D001388:Aziridines; D011810:Quinoxalines; D010165:Palladium