title: [Correlation analysis of computed tomography imaging scoring to the presence of acute kidney injury in severe acute pancreatitis].
abstract: OBJECTIVE
  To investigate the multi-detector-row spiral CT (MDCT) imaging findings of severe acute pancreatitis (SAP) complicated with acute kidney injury (AKI), and to evaluate the correlation of MDCT imaging scoring to the presence of AKI in SAP.
  
  
  METHODS
  One hundred and nineteen patients with confirmed diagnosis of SAP during March 2008-December 2010 in our hospital were retrospectively included into the study. The imaging features including pancreatic size, areas and degrees of pancreatic necrosis, peripancreatic retroperitoneal and intraperitoneal inflammation and other organs involvement (liver, kidney, spleen, gastrointestinal tract, etc.) were observed, as well as related CT severity indexes such as Balthazar CT score, CT severity index (CTSI) and extra-pancreatic inflammation on CT (EPIC) score were calculated. At the mean time, the clinical data including serum creatinine, urine output and the eventual prognosis were collected and compared with CT indexes, which was used for statistical analysis.
  
  
  RESULTS
  SAP with AKI patients were often associated with the high incidence of multiple organ dysfunction (MODS) (88.1%) and high mortality (47.6%). In SAP with AKI patients, the CT indexes were significantly higher than those of SAP without AKI patients. Among the CT indexes, EPIC score showed the larger area under the ROC curve (AUC = 0.903) than CTSI score (AUC = 0.721) and Balthazar CT score (AUC = 0.571).
  
  
  CONCLUSIONS
  Among the CT indexes, EPIC score has a better prediction of AKI in SAP patients than CTSI and Balthazar CT scores.
authors: Department of Radiology, West China Hospital, Sichuan University, Chengdu 610041, China.
authors: Zheng-Yan
authors: ZY
authors: Li
authors: Ling
authors: L
authors: Zhang
authors: Tao
authors: T
authors: Jin
authors: Zi-Xing
authors: ZX
authors: Huang
authors: Bin
authors: B
authors: Song
authors: Bi
authors: B
authors: Wu
authors: Wei-Wei
authors: WW
authors: Zhang
authors: Huan-Huan
authors: HH
authors: Zhong
authors: Xi-Jiao
authors: XJ
authors: Liu
authors: Dan
authors: D
authors: Liu
mesh_terms: D058186:Acute Kidney Injury / Q000000981:diagnostic imaging* / Q000209:etiology*; D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D019283:Pancreatitis, Acute Necrotizing / Q000150:complications* / Q000000981:diagnostic imaging*; D010538:Peritonitis / Q000000981:diagnostic imaging; D012189:Retrospective Studies; D013223:Statistics as Topic; D036542:Tomography, Spiral Computed / Q000379:methods*; D055815:Young Adult