title: [Outcome of differentiated thyroid cancer after initial treatment].
abstract: Incidence of differentiated thyroid cancer has increased in the last two decades. This type of cancer is now being diagnosed at an earlier stage. Treatment strategy has been modified.
  
  
  OBJECTIVE
  The goals of this study were to analyze the outcome of differentiated thyroid cancer after initial treatment (surgery and radioiodine ablation) in patients evaluated and followed up in a single centre between l999 and 2009, to compare these results with others as well as to monitor the adoption of international recommendation. 107 patients having T1-T2 differentiated thyroid cancer were studied. Mean follow-up time was 63 months.
  
  
  RESULTS
  After surgery patients were prepared using thyroid hormone withdrawal or recombinant human thyrotropin, then 1.1-3.7 GBq 131-iodine was administered. First year evaluation consisted of ultrasound as well as serum thyrotropin and thyroglobulin (plus thyroglobulin antibody) determinations. Ablation success rate was 83% and the five year survival was 100%. There was not any cancer specific death.
  
  
  CONCLUSIONS
  In the future somewhat more radical surgery and less remnant ablation is needed with unified follow-up protocol.
authors: Jávorszky Ödön Kórház Vác Argenti Döme tér 1-3. 2600. 2konrady@invitel.hu
authors: András
authors: A
authors: Konrády
authors: Zsuzsa
authors: Z
authors: Bencsik
authors: Zoltán
authors: Z
authors: Locsey
authors: Tamás
authors: T
authors: Bénik
mesh_terms: D018263:Adenocarcinoma, Follicular / Q000628:therapy; D000328:Adult; D000368:Aged; D002277:Carcinoma / Q000097:blood / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000473:pathology / Q000628:therapy*; D002291:Carcinoma, Papillary / Q000628:therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006814:Hungary / Q000453:epidemiology; D007457:Iodine Radioisotopes / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D018714:Radiotherapy, Adjuvant; D012086:Reoperation; D016019:Survival Analysis; D013954:Thyroglobulin / Q000097:blood; D013964:Thyroid Neoplasms / Q000097:blood / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000473:pathology / Q000628:therapy*; D013965:Thyroidectomy; D013972:Thyrotropin / Q000097:blood; D016896:Treatment Outcome; D014463:Ultrasonography
chemical_list: D007457:Iodine Radioisotopes; D013972:Thyrotropin; D013954:Thyroglobulin