title: Clinical and serological features of patients with suspected Lyme borreliosis.
abstract: Serology is currently the method of choice for the laboratory diagnosis of Lyme Borreliosis, but it must be interpreted with caution. A total of 954 patients with suspected Lyme borreliosis were evaluated on the basis of clinical and serological data. The seroprevalence of Borrelia burgdorferi antibodies was 4.4% (42 of the 954 serum samples). The most frequent clinical manifestation was erythema migrans which occurred in 50% of the seropositive patients, followed by neuroborreliosis (16.6%) and arthritis (11.9%). Carditis was rare. Our findings suggest that for the diagnosis of Lyme borreliosis, serologic tests need to be combined with clinical signs and symptoms.
authors: Iolanda
authors: I
authors: Santino
authors: V
authors: V
authors: Longobardi
mesh_terms: D000328:Adult; D000907:Antibodies, Bacterial / Q000032:analysis; D001168:Arthritis / Q000209:etiology; D015153:Blotting, Western; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005929:Glossitis, Benign Migratory / Q000175:diagnosis / Q000209:etiology; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D008193:Lyme Disease / Q000150:complications / Q000175:diagnosis* / Q000276:immunology; D008297:Male; D012698:Serologic Tests
chemical_list: D000907:Antibodies, Bacterial; D007074:Immunoglobulin G; D007075:Immunoglobulin M