title: Base promoted synthesis of activated cyclopropanes bearing homologated carbonyl groups via tandem Michael addition-intramolecular enolate trapping.
abstract: A simple base promoted intramolecular Michael initiated ring closure reaction of γ-hydroxyenone derived diphenyl phosphinates with 1,3-indandione, enabled the synthesis of novel activated cyclopropanes with homologated carbonyl moiety in good yield. Promising levels of enantioselectivity are achieved when using cinchona derivatives as promoters.
authors: Dipartimento di Chimica e Biologia, Fisciano, Italy.
authors: Alessio
authors: A
authors: Russo
authors: Alessandra
authors: A
authors: Lattanzi