title: From pharmacovigilance to therapy amelioration in paediatric patients: the role of the clinical pharmacologists and family paediatricians. Part of a series on Paediatric Pharmacology, guest edited by Gianvincenzo Zuccotti, Emilio Clementi, and Massimo Molteni.
abstract: An active pharmacovigilance approach is advisable in paediatric pharmacotherapy as it contributes to generate knowledge promptly and to enhance the estimation of true risk in clinical practice. Reports and studies from the scientific community and regulatory agencies have shown that effective methods for early detection of adverse drug reaction and pharmacoepidemiological studies are a primary need since they increase drug safety in the paediatric population. In this perspective article we describe how pharmacologists and paediatricians may actively synergise to optimise drug therapies and their management in paediatric patients.
authors: Italian Paediatric Federation and FIMP-MCRN (Family Paediatricians-Medicines for Children Research Network), Rome, Italy.
authors: Ettore
authors: E
authors: Napoleone
authors: Sonia
authors: S
authors: Radice
mesh_terms: D016907:Adverse Drug Reaction Reporting Systems; D019468:Disease Management; D064420:Drug-Related Side Effects and Adverse Reactions; D006801:Humans; D010372:Pediatrics / Q000379:methods*; D010595:Pharmacists; D060735:Pharmacovigilance; D010821:Physicians, Family