title: Multimodal treatment for multistation mediastinal lymph node adenocarcinoma: a case report.
abstract: We report on a 68-year-old male with a multistation mediastinal lymph node adenocarcinoma, who had no primary lesions occurring within 48 months. After diagnosis by lymph node biopsy via right-sided thoracoscopy, the bilateral mediastinal lymphadenopathy responded to platinum-based chemotherapy. At 30 months after completion of chemotherapy, left mediastinal lymphadenopathy recurred. Left anterior mediastinal dissection via left-sided thoracoscopy was successful. After surgery, the patient did well with no primary lesions for more than a year. The etiology of mediastinal lymph node carcinoma of unknown origin is discussed.
authors: Department of General Thoracic Surgery, Jichi Medical University, Shimotsuke, Tochigi, Japan. tcvnknt@jichi.ac.jp
authors: Tomoyuki
authors: T
authors: Nakano
authors: Shunsuke
authors: S
authors: Endo
authors: Tetsuya
authors: T
authors: Endo
authors: Tsuyoshi
authors: T
authors: Hasegawa
authors: Masayuki
authors: M
authors: Nakayama
authors: Yukihiko
authors: Y
authors: Sugiyama
authors: Mitsugu
authors: M
authors: Hironaka
mesh_terms: D000230:Adenocarcinoma / Q000737:chemistry / Q000556:secondary / Q000628:therapy*; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D014408:Biomarkers, Tumor / Q000032:analysis; D001706:Biopsy; D017024:Chemotherapy, Adjuvant; D002945:Cisplatin / Q000008:administration & dosage; D006801:Humans; D007150:Immunohistochemistry; D008197:Lymph Node Excision / Q000379:methods; D008198:Lymph Nodes / Q000737:chemistry / Q000187:drug effects* / Q000473:pathology / Q000601:surgery*; D008207:Lymphatic Metastasis; D008297:Male; D064847:Multimodal Imaging; D009382:Neoplasms, Unknown Primary / Q000737:chemistry / Q000473:pathology / Q000628:therapy*; D017239:Paclitaxel / Q000008:administration & dosage; D049268:Positron-Emission Tomography; D012008:Recurrence; D012086:Reoperation; D013906:Thoracoscopy; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D014408:Biomarkers, Tumor; D017239:Paclitaxel; D002945:Cisplatin