title: A facile transformation of amino acids to functionalized coumarins.
abstract: The synthesis of novel chiral coumarins functionalized with proteinogenic amino acid side chains via N-protected γ-amino-β-keto esters and their incorporation into the cell permeable HIV-1 TAT peptide through the modified solid phase peptide synthesis are described.
authors: Department of Chemistry, Indian Institute of Science Education and Research, Pashan, Pune 411021, India.
authors: Anupam
authors: A
authors: Bandyopadhyay
authors: Hosahudya N
authors: HN
authors: Gopi
mesh_terms: D000596:Amino Acids / Q000737:chemistry*; D045744:Cell Line, Tumor; D003374:Coumarins / Q000138:chemical synthesis*; D015696:Gene Products, tat / Q000138:chemical synthesis; D015497:HIV-1 / Q000737:chemistry; D006801:Humans; D008958:Models, Molecular; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D000596:Amino Acids; D003374:Coumarins; D015696:Gene Products, tat