title: Are dysregulated inflammatory responses to commensal bacteria involved in the pathogenesis of hepatobiliary-pancreatic autoimmune disease? An analysis using mice models of primary biliary cirrhosis and autoimmune pancreatitis.
abstract: The etiopathogenesis of many autoimmune disorders has not been identified. The aim of this paper is to focus on the involvement of bacterial exposure in the pathogenesis of primary biliary cirrhosis (PBC) and autoimmune pancreatitis (AIP), both of which are broadly categorized as autoimmune disorders involving hepatobiliary-pancreatic lesions. Avirulent and/or commensal bacteria, which may have important role(s) as initiating factors in the pathogenesis of autoimmune disorders such as PBC and AIP, will be emphasized.
authors: Departments of Infection Control Science and Bacteriology, School of Medicine, Juntendo University, Tokyo 113-8421, Japan Departments of Microbiology and Immunology, Tokyo Women's Medical University, 8-1 Kawada-cho, Shinjuku-ku, Tokyo, Japan.
authors: Naoko
authors: N
authors: Yanagisawa
authors: Ikuko
authors: I
authors: Haruta
authors: Ken
authors: K
authors: Kikuchi
authors: Noriyuki
authors: N
authors: Shibata
authors: Junji
authors: J
authors: Yagi