title: Mussel-inspired chemistry for robust and surface-modifiable multilayer films.
abstract: In this article, we report a bioinspired approach to preparing stable, functional multilayer films by the integration of mussel-inspired catechol oxidative chemistry into a layer-by-layer (LbL) assembly. A polyanion of poly(acrylic acid-g-dopamine) (PAA-dopamine) bearing catechol groups, a mussel adhesive protein-mimetic polymer, was synthesized as the building block for LbL assembly with poly(allylamine hydrochloride) (PAH). The oxidization of the incorporated catechol group under mild oxidative condition yields o-quinone, which exhibits high reactivity with amine and catechol, thus endowing the chemical covalence and retaining the assembled morphology of multilayer films. The cross-linked films showed excellent stability even in extremely acidic, basic, and highly concentrated aqueous salt solutions. The efficient chemical cross-linking allows for the production of intact free-standing films without using a sacrificial layer. Moreover, thiol-modified multilayer films with good stability were exploited by a combination of thiols-catechol addition and then oxidative cross-linking. The outstanding stability under harsh conditions and the facile functionalization of the PAA-dopamine/PAH multilayer films make them attractive for barriers, separation, and biomedical devices.
authors: Beijing National Laboratory for Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, PR China.
authors: Junjie
authors: J
authors: Wu
authors: Liang
authors: L
authors: Zhang
authors: Yongxin
authors: Y
authors: Wang
authors: Yuhua
authors: Y
authors: Long
authors: Huan
authors: H
authors: Gao
authors: Xiaoli
authors: X
authors: Zhang
authors: Ning
authors: N
authors: Zhao
authors: Yuanli
authors: Y
authors: Cai
authors: Jian
authors: J
authors: Xu
mesh_terms: D000818:Animals; D049872:Bivalvia / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D018625:Microscopy, Atomic Force; D008855:Microscopy, Electron, Scanning; D010084:Oxidation-Reduction; D011073:Polyamines / Q000737:chemistry; D013056:Spectrophotometry, Ultraviolet; D013499:Surface Properties
chemical_list: D011073:Polyamines; C063994:polyallylamine