title: C-Reactive protein-directed immobilization of phosphocholine ligands on a solid surface.
abstract: The complexes of C-reactive protein (CRP) with its polymerizable phosphocholine ligands adsorbed at the styrene-water interface were polymerized. The molecularly imprinted polymer (MIP) exhibited a binding affinity for CRP comparable to that of immobilized anti-CRP antibody. The determination of human serum CRP using the MIP-based sandwich immunoassay has been demonstrated.
authors: Nano & Bio Research Division, Daegu Gyeongbuk Institute of Science and Technology (DGIST), Daegu 711-873, Korea.
authors: Eunjoo
authors: E
authors: Kim
authors: Hyun-Chul
authors: HC
authors: Kim
authors: Se Geun
authors: SG
authors: Lee
authors: Sung Jun
authors: SJ
authors: Lee
authors: Tae-Jung
authors: TJ
authors: Go
authors: Chul Su
authors: CS
authors: Baek
authors: Sang Won
authors: SW
authors: Jeong
mesh_terms: D055910:Antibodies, Immobilized / Q000276:immunology; D002097:C-Reactive Protein / Q000032:analysis* / Q000276:immunology; D006801:Humans; D007118:Immunoassay / Q000379:methods*; D008024:Ligands; D054802:Molecular Imprinting; D009821:Oils / Q000737:chemistry; D010767:Phosphorylcholine / Q000737:chemistry*; D011137:Polystyrenes / Q000737:chemistry; D013499:Surface Properties; D014867:Water / Q000737:chemistry
chemical_list: D055910:Antibodies, Immobilized; D008024:Ligands; D009821:Oils; D011137:Polystyrenes; D014867:Water; D010767:Phosphorylcholine; D002097:C-Reactive Protein