title: Vasculitis of dental pulp associated with cryoglobulinemia in hepatitis C virus patients: case report.
abstract: BACKGROUND
  This report presents a case of impacted lower third molar extracted for surgical reasons in patient with uncontrolled hepatitis C. After decalcification, dental pulp vasculature and its tissue quality were investigated.
  
  
  METHODS
  Serial sections of 4-μm thickness along the midline buccolingually for the demineralized specimen were obtained, mounted on a glass slide, stained with hematoxylin-eosin, covered, and viewed under the light microscope.
  
  
  RESULTS
  The histologic investigation of the pulp tissue revealed thickening, stenosis, and occlusion of the vessel wall, ectopic calcification of the pulp tissue in close association with pulpal blood vessels, interrupted and vacuolated odontoblastic layer in the coronal pulp chamber, with an inflammatory cell infiltrate throughout the pulpal tissue.
  
  
  CONCLUSIONS
  Cryoglobulinemia associated with uncontrolled hepatitis C virus infection in patients endangers the dental pulp vasculature and alters its normal tissue architecture.
authors: Oral Biology Department, Faculty of Dentistry, Mansoura University, Mansoura, Dakahlia, Egypt. Grawish2005@yahoo.com
authors: Mohammed El-Awady
authors: Mel-A
authors: Grawish
authors: Ahmed Ragheb
authors: AR
authors: Zaher
authors: Heba M
authors: HM
authors: Elsabaa
authors: Doha
authors: D
authors: Hegazy
mesh_terms: D000328:Adult; D003449:Cryoglobulinemia / Q000150:complications* / Q000821:virology; D003782:Dental Pulp / Q000098:blood supply*; D003784:Dental Pulp Calcification / Q000150:complications*; D004534:Egypt; D016174:Hepacivirus / Q000472:pathogenicity; D019698:Hepatitis C, Chronic / Q000150:complications*; D006801:Humans; D008297:Male; D008964:Molar, Third / Q000473:pathology / Q000601:surgery; D014081:Tooth Extraction; D014095:Tooth, Impacted / Q000150:complications / Q000601:surgery; D014657:Vasculitis / Q000150:complications*