title: Binaphthol-catalyzed asymmetric conjugate arylboration of enones.
abstract: Conjugate addition of arylboronates to α,β-unsaturated ketones may be catalyzed by chiral binaphthols with enantioselectivities of up to 99:1. Best results were observed with 3,3'-dichloro-BINOL. This chemistry was applied to syntheses of intermediates for syntheses of (+)-indatraline and (+)-tolterodine.
authors: Guelph-Waterloo Centre for Graduate Work in Chemistry and Biochemistry, (GWC)2, Department of Chemistry, University of Waterloo, Waterloo, Ontario, Canada N2L 3G1.
authors: Heather M
authors: HM
authors: Turner
authors: Jignesh
authors: J
authors: Patel
authors: Nootaree
authors: N
authors: Niljianskul
authors: J Michael
authors: JM
authors: Chong