title: Is there circadian variation in cortisol levels in young sows in heart catheterization?
abstract: Cortisol is the main glucocorticoid (GC) hormone in pigs associated             with stress response. It is well known that GCs levels are not stable during the             day; their concentration is a circadian variable with the peak in the morning and             the nadir in the night (in diurnal animals). Circadian variation is present during             postnatal ontogeny. The onset of the circadian fluctuation occurs in pigs at the             age of 3 to 20 weeks (according to the literature). The aim of our pilot study             was to determine if young sows (used in cardiosurgical experiments) already             developed the circadian variation. Twelve-week-old sows were used in the heart             catheterization experiment. Cortisol was measured during four different stages of             the experiment at two different times of the day (the operation was performed             in the morning or afternoon). To determine circadian variation the Mann-Whitney             test was used; to determine changes in cortisol levels within the experiment the             Friedman test was performed. We didn't find any circadian variation (p>0.05) or             statistical significant variation in the Friedman test (p>0.05). We assumed that             our pigs are too young to have circadian rhythm present. Our findings are in             accordance with many authors.
authors: Institute of Physiology, Charles University, Prague, Czech Republic. hana.skarlandtova@lf1.cuni.cz
authors: H
authors: H
authors: Skarlandtová
authors: M
authors: M
authors: Bičíková
authors: P
authors: P
authors: Neužil
authors: M
authors: M
authors: Mlček
authors: V
authors: V
authors: Hrachovina
authors: T
authors: T
authors: Svoboda
authors: E
authors: E
authors: Medová
authors: J
authors: J
authors: Kudlička
authors: A
authors: A
authors: Dohnalová
authors: S
authors: S
authors: Havránek
authors: H
authors: H
authors: Kazihnítková
authors: L
authors: L
authors: Máčová
authors: O
authors: O
authors: Kittnar
mesh_terms: D000818:Animals; D006328:Cardiac Catheterization; D002940:Circadian Rhythm; D005260:Female; D006854:Hydrocortisone / Q000097:blood*; D034421:Sus scrofa
chemical_list: D006854:Hydrocortisone