title: Transglutaminases and receptor tyrosine kinases.
abstract: Transglutaminases are confounding enzymes which are known to play key roles in various cellular processes. In this paper, we aim to bring together several pieces of evidence from published research and literature that suggest a potentially vital role for transglutaminases in receptor tyrosine kinases (RTK) signalling. We cite literature that confirms and suggests the formation of integrin:RTK:transglutaminase complexes and explores the occurrence and functionality of these complexes in a large fraction of the RTK family.
authors: Tissue Repair and Regeneration Program, Institute of Health and Biomedical Innovation, Queensland University of Technology, 60 Musk Ave, Kelvin Grove Qld 4059, Australia. manaswini.s@student.qut.edu.au
authors: Manaswini
authors: M
authors: Sivaramakrishnan
authors: Gary K
authors: GK
authors: Shooter
authors: Zee
authors: Z
authors: Upton
authors: Tristan I
authors: TI
authors: Croll
mesh_terms: D016326:Extracellular Matrix Proteins / Q000502:physiology; D006801:Humans; D016023:Integrins / Q000502:physiology; D060066:Protein Interaction Maps; D020794:Receptor Protein-Tyrosine Kinases / Q000502:physiology*; D015398:Signal Transduction; D011503:Transglutaminases / Q000502:physiology*
chemical_list: D016326:Extracellular Matrix Proteins; D016023:Integrins; D011503:Transglutaminases; D020794:Receptor Protein-Tyrosine Kinases