title: New bioactive macrocyclic diterpenoids from Jatropha multifida.
abstract: Two new macrocyclic diterpenoids, multifidanol (1) and multifidenol (2) along with several known compounds have been isolated from the stem of Jatropha multifida. The structures of the new compounds were established from the extensive studies of their 1D and 2D NMR spectra. The cytotoxic and antimicrobial activities of these two constituents were examined.
authors: Organic Chemistry Division-I, Indian Institute of Chemical Technology, Hyderabad 500 607, India.
authors: Boddu Shashi
authors: BS
authors: Kanth
authors: Avula Satya
authors: AS
authors: Kumar
authors: Digambar Balaji
authors: DB
authors: Shinde
authors: Kothapalli Hari
authors: KH
authors: Babu
authors: Tuniki Venugopal
authors: TV
authors: Raju
authors: Chityal Ganesh
authors: CG
authors: Kumar
authors: Pombala
authors: P
authors: Sujitha
authors: Biswanath
authors: B
authors: Das
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects; D001424:Bacterial Infections / Q000188:drug therapy; D045744:Cell Line, Tumor; D004224:Diterpenes / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D006801:Humans; D031286:Jatropha / Q000737:chemistry*; D047028:Macrocyclic Compounds / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D009369:Neoplasms / Q000188:drug therapy
chemical_list: D000900:Anti-Bacterial Agents; D000972:Antineoplastic Agents, Phytogenic; D004224:Diterpenes; D047028:Macrocyclic Compounds