title: Obstructive sleep apnea and the risk of adverse pregnancy outcomes.
abstract: OBJECTIVE
  We examined the risk of adverse pregnancy outcomes, including low birthweight (LBW), preterm birth, small for gestational age (SGA), cesarean section (CS), low Apgar score (at 5 minutes after delivery), and preeclampsia in pregnant women with and without obstructive sleep apnea (OSA).
  
  
  METHODS
  Our subjects included 791 women with OSA and 3955 randomly selected women without OSA. We performed conditional logistic regression analyses to examine the risks of adverse pregnancy outcomes between women with and without OSA.
  
  
  RESULTS
  Compared with women without OSA, adjusted odds ratios for LBW, preterm birth, SGA infants, CS, and preeclampsia in women with OSA were 1.76 (95% confidence interval [CI], 1.28-2.40), 2.31 (95% CI, 1.77-3.01), 1.34 (95% CI, 1.09-1.66), 1.74 (95% CI, 1.48-2.04), and 1.60 (95% CI, 2.16-11.26), respectively.
  
  
  CONCLUSIONS
  Pregnant women with OSA are at increased risk for having LBW, preterm, and SGA infants, CS, and preeclampsia, compared with pregnant women without OSA.
authors: School of Public Health, Taipei Medical University, Taipei, Taiwan.
authors: Yi-Hua
authors: YH
authors: Chen
authors: Jiunn-Horng
authors: JH
authors: Kang
authors: Ching-Chun
authors: CC
authors: Lin
authors: I-Te
authors: IT
authors: Wang
authors: Joseph J
authors: JJ
authors: Keller
authors: Herng-Ching
authors: HC
authors: Lin
mesh_terms: D000293:Adolescent; D000328:Adult; D003430:Cross-Sectional Studies; D016208:Databases, Factual; D005260:Female; D006801:Humans; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D008875:Middle Aged; D011225:Pre-Eclampsia / Q000209:etiology*; D011247:Pregnancy; D011256:Pregnancy Outcome; D047928:Premature Birth / Q000209:etiology*; D012306:Risk; D020181:Sleep Apnea, Obstructive / Q000150:complications*