title: Design and synthesis of catenated rings based on toroidal DNA structures.
abstract: Strand proximity and self-crossing that occur intrinsically in the relaxed forms of toroidal DNA are utilized unprecedentedly in our investigations for creating catenated DNA rings. In addition, our current studies show that the geometrical shapes of our newly obtained catenated DNA circles as well as their topological arrangements are vividly visible under atomic force microscopic examination.
authors: Division of Chemistry and Biological Chemistry, Nanyang Technological University, 21 Nanyang Link, Singapore 637371.
authors: Zhaoqi
authors: Z
authors: Yang
authors: Dawei
authors: D
authors: Li
authors: Tianhu
authors: T
authors: Li
mesh_terms: D055162:Biocatalysis; D043864:DNA, Catenated / Q000096:biosynthesis / Q000737:chemistry*; D004270:DNA, Circular / Q000737:chemistry*; D019426:Integrases / Q000378:metabolism; D018625:Microscopy, Atomic Force
chemical_list: D043864:DNA, Catenated; D004270:DNA, Circular; C045073:Cre recombinase; D019426:Integrases