title: MRI-guided vascular access with an active visualization needle.
abstract: OBJECTIVE
  To develop an approach to vascular access under magnetic resonance imaging (MRI), as a component of comprehensive MRI-guided cardiovascular catheterization and intervention.
  
  
  METHODS
  We attempted jugular vein access in healthy pigs as a model of "difficult" vascular access. Procedures were performed under real-time MRI guidance using reduced field of view imaging. We developed an "active" MRI antenna-needle having an open-lumen, distinct tip appearance and indicators of depth and trajectory in order to enhance MRI visibility during the procedure. We compared performance of the active needle against an unmodified commercial passively visualized needle, measured by procedure success among operators with different levels of experience.
  
  
  RESULTS
  MRI-guided central vein access was feasible using both the active needle and the unmodified passive needle. The active needle required less time (88 vs. 244 sec, P = 0.022) and fewer needle passes (4.5 vs. 9.1, P = 0.028), irrespective of operator experience.
  
  
  CONCLUSIONS
  MRI-guided access to central veins is feasible in our animal model. When image guidance is necessary for vascular access, performing this component under MRI will allow wholly MRI-guided catheterization procedures that do not require adjunctive imaging facilities such as x-ray or ultrasound. The active needle design showed enhanced visibility, as expected. These capabilities may permit more complex catheter-based cardiovascular interventional procedures enabled by enhanced image guidance.
authors: Cardiovascular and Pulmonary Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland 20892-1061, USA.
authors: Christina E
authors: CE
authors: Saikus
authors: Kanishka
authors: K
authors: Ratnayaka
authors: Israel M
authors: IM
authors: Barbash
authors: Jessica H
authors: JH
authors: Colyer
authors: Ozgur
authors: O
authors: Kocaturk
authors: Anthony Z
authors: AZ
authors: Faranesh
authors: Robert J
authors: RJ
authors: Lederman
mesh_terms: D000792:Angiography / Q000379:methods; D000818:Animals; D002309:Cardiology / Q000379:methods; D002404:Catheterization; D002405:Catheterization, Central Venous / Q000295:instrumentation / Q000379:methods*; D002983:Clinical Competence; D003952:Diagnostic Imaging / Q000379:methods*; D004867:Equipment Design; D007601:Jugular Veins / Q000473:pathology*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D009339:Needles; D015203:Reproducibility of Results; D013552:Swine