title: Thermotherapy: a novel possible treatment strategy of chronic rhinosinusitis based on the chilblain-like alteration in the early pathophysiology.
abstract: Chronic rhinosinusitis (CRS) is one of the most common inflammatory diseases affecting large number of patients globally. The pathogenesis of CRS is still unclear and the treatment is unsatisfied. Clinical data provide the evidence that the chilblain-like alteration occurs in the early pathophysiology of CRS. We hypothesize that thermotherapy may offer a novel possible treatment strategy of chronic rhinosinusitis. In this article, we discuss the possibility of the chilblain-like alteration in the early pathophysiology and a therapeutic role of thermotherapy.
authors: Key Laboratory of Nuclear Medicine, Ministry of Health, Jiangsu Key Laboratory of Molecular Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wuxi, Jiangsu 214063, China. dylizhong@126.com
authors: Zhong
authors: Z
authors: Li
mesh_terms: D002647:Chilblains / Q000503:physiopathology; D006801:Humans; D006979:Hyperthermia, Induced / Q000379:methods*; D008954:Models, Biological; D012220:Rhinitis / Q000503:physiopathology* / Q000628:therapy*; D012852:Sinusitis / Q000503:physiopathology* / Q000628:therapy*