title: Asymmetric reduction of ketones with recombinant E. coli whole cells in neat substrates.
abstract: The asymmetric reduction of ketones is performed by using lyophilized whole cells in neat substrates with defined water activity (a(w)). Ketones and alcohols prone to be unstable in aqueous media can now be converted via biocatalysis.
authors: Lehrstuhl für Biotechnology, RWTH Aachen University, Worringer Weg 1, D-52074 Aachen, Germany.
authors: Andre
authors: A
authors: Jakoblinnert
authors: Radoslav
authors: R
authors: Mladenov
authors: Albert
authors: A
authors: Paul
authors: Fabrizio
authors: F
authors: Sibilla
authors: Ulrich
authors: U
authors: Schwaneberg
authors: Marion B
authors: MB
authors: Ansorge-Schumacher
authors: Pablo Domínguez
authors: PD
authors: de María
mesh_terms: D019840:2-Propanol / Q000378:metabolism; D000098:Acetophenones / Q000378:metabolism; D000429:Alcohol Oxidoreductases / Q000235:genetics / Q000378:metabolism*; D000449:Aldehyde Reductase; D000074408:Aldo-Keto Reductases; D055162:Biocatalysis; D002175:Candida / Q000201:enzymology; D004926:Escherichia coli / Q000235:genetics / Q000378:metabolism*; D007659:Ketones / Q000378:metabolism*; D010084:Oxidation-Reduction; D011994:Recombinant Proteins / Q000378:metabolism
chemical_list: D000098:Acetophenones; D007659:Ketones; D011994:Recombinant Proteins; D000429:Alcohol Oxidoreductases; D000074408:Aldo-Keto Reductases; D000449:Aldehyde Reductase; D019840:2-Propanol; C038699:acetophenone