title: Evaluation of 532-nm KTP laser treatment efficacy on acne vulgaris with once and twice weekly applications.
abstract: BACKGROUND
  Light-based therapies and lasers have been proposed for the treatment of acne vulgaris but the efficacy and application periods of 532-nm KTP laser treatment are not clear.
  
  
  OBJECTIVE
  To evaluate the efficacy and safety of 532-nm KTP laser and compare the effects of once and twice weekly applications in the treatment of mild to moderate acne vulgaris.
  
  
  METHODS
  Totally 38 patients were treated once weekly and twice weekly in group I and in group II respectively. One half of the face of each patient was treated with 532-nm KTP and the other half was remained as untreated. Patients were evaluated at the beginning, one and four weeks after the last treatment session with Michaëlsson acne severity grading score (MASS).
  
  
  RESULTS
  Statistically significant improvement was found at second control (p = 0.005) in group I, and at the first (p = 0.004), and second (p < 0.001) controls in group II for treated sides. For both groups, changes of MASS were insignificant for untreated sites. Improvement of MASS of treated sides was not statistically significant between two treatment groups for both controls.
  
  
  CONCLUSIONS
  532-nm KTP laser treatment may be an alternative method in selected acne vulgaris patients. No significant difference was noted between once and twice weekly applications.
authors: Department of Dermatology, School of Medicine, Ondokuz Mayis University, Samsun, Turkey.
authors: Ozlem
authors: O
authors: Yilmaz
authors: Nilgun
authors: N
authors: Senturk
authors: Esra Pancar
authors: EP
authors: Yuksel
authors: Fatma
authors: F
authors: Aydin
authors: Muge Guler
authors: MG
authors: Ozden
authors: Tayyar
authors: T
authors: Canturk
authors: Ahmetyasar
authors: A
authors: Turanli
mesh_terms: D000152:Acne Vulgaris / Q000473:pathology / Q000532:radiotherapy*; D005145:Face; D005260:Female; D006801:Humans; D053844:Lasers, Solid-State / Q000627:therapeutic use*; D028022:Low-Level Light Therapy; D008297:Male; D012720:Severity of Illness Index; D016896:Treatment Outcome; D055815:Young Adult