title: Papuamides E and F, Cytotoxic Depsipeptides from the Marine Sponge Melophlus sp.
abstract: Two known papuamides C (1) and D (2) together with two new depsipeptides, papuamides E (3) and F (4), were isolated from an undescribed sponge of the genus Melophlus collected in the Solomon Islands. The planar structures of the compounds were elucidated on the basis of spectroscopic studies. Papuamides C-F (1-4) showed cytotoxicity against brine shrimp with LD(50) values between 92 and 106 μg/mL.
authors: Institute of Applied Science, Faculty of Science, Technology and Environment, The University of the South Pacific, Laucala Campus, Suva, Fiji Islands.
authors: Pritesh
authors: P
authors: Prasad
authors: William
authors: W
authors: Aalbersberg
authors: Klaus-D
authors: KD
authors: Feussner
authors: Ryan M
authors: RM
authors: Van Wagoner