title: Comparison between Alzheimer's disease and subcortical vascular dementia: attentional cortex study in functional magnetic resonance imaging.
abstract: Blood oxygen level dependent functional magnetic resonance imaging (fMRI) and the Stroop test were used to assess attentional cortex activation in patients with Alzheimer's disease, subcortical vascular dementia, and normal control subjects. Patients with Alzheimer's disease and subcortical  vascular dementia demonstrated similar locations of cortical activation, including the bilateral middle and inferior frontal gyri, anterior cingulate and inferior parietal lobule in response to Stroop colour word stimuli. This activation was distinctly decreased in patients with dementia compared  with normal control subjects. Different regions of the brain were activated in patients with Alzheimer's disease and subcortical vascular dementia compared with normal controls. fMRI is a useful tool for the study of dementia in humans and has some potential diagnostic value. Further studies  with larger numbers of participants are required.
authors: Department of Radiology, Southwest Hospital, Third Military Medical University, Chongqing, China. li_chuanming@yeah.net
authors: C
authors: C
authors: Li
authors: J
authors: J
authors: Zheng
authors: J
authors: J
authors: Wang
authors: L
authors: L
authors: Gui
mesh_terms: D000368:Aged; D000544:Alzheimer Disease / Q000473:pathology*; D001288:Attention; D016022:Case-Control Studies; D015140:Dementia, Vascular / Q000473:pathology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D057190:Stroop Test