title: Low-grade myofibroblastic sarcoma of the maxillary region in a dog.
abstract: A subcutaneous tumour was identified in the maxillary region of a 14-year-old mixed breed dog. This tumour had grown rapidly over 2 weeks. Microscopically, the tumour had ill-defined borders and was composed of bundles and whorls of atypical spindle cells accompanied by abundant collagen fibres. Immunohistochemically, neoplastic cells were immunoreactive for vimentin, α-smooth muscle actin and calponin and negative for S100 protein, von Willebrand factor, desmin and smoothelin. These results suggested that the neoplastic cells were derived from myofibroblasts and that the tumour was a low-grade myofibroblastic sarcoma.
authors: Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology, Tokyo, Japan.
authors: T
authors: T
authors: Tsuchiya
authors: K
authors: K
authors: Suzuki
authors: Y
authors: Y
authors: Hojo
authors: A
authors: A
authors: Shiraki
authors: M
authors: M
authors: Imaoka
authors: M
authors: M
authors: Shibutani
authors: K
authors: K
authors: Mitsumori
mesh_terms: D000199:Actins / Q000378:metabolism; D000818:Animals; D014408:Biomarkers, Tumor / Q000378:metabolism; D002135:Calcium-Binding Proteins / Q000378:metabolism; D004283:Dog Diseases / Q000378:metabolism / Q000473:pathology*; D004285:Dogs; D005354:Fibrosarcoma / Q000378:metabolism / Q000473:pathology / Q000662:veterinary*; D007150:Immunohistochemistry / Q000379:methods / Q000662:veterinary; D008297:Male; D008441:Maxillary Neoplasms / Q000378:metabolism / Q000473:pathology / Q000662:veterinary*; D008840:Microfilament Proteins / Q000378:metabolism; D058628:Myofibroblasts / Q000378:metabolism / Q000473:pathology; D009217:Myosarcoma / Q000378:metabolism / Q000473:pathology / Q000662:veterinary*; D014746:Vimentin / Q000378:metabolism; D000096985:Calponins
chemical_list: D000199:Actins; D014408:Biomarkers, Tumor; D002135:Calcium-Binding Proteins; D008840:Microfilament Proteins; D014746:Vimentin; D000096985:Calponins