title: Quantifying stranded implant displacement following prostate brachytherapy.
abstract: We aim to compute radioactive stranded-implant displacement during and after prostate brachytherapy. We present the methods used to identify corresponding seeds in planned, intra-operative and postimplant patient data that enable us to compute seed displacements. A minimum cost network flow algorithm is used, on 8 patients, for needle track detection to group seeds into needles that can be matched between datasets. An iterative best line detection algorithm is used both to help with needle detection and to register the different datasets. Our results show that there was an average seed misplacement of 5.08 +/- 2.35 mm during the procedure, which then moved another 3.10 +/- 1.91 mm by the time the quality assurance CT was taken. Several directional trends in different regions of the prostate were noted and commented on.
authors: Department of Electrical and Computer Engineering, University of British Columbia, Vancouver, Canada. juliol@ece.ubc.ca
authors: Julio
authors: J
authors: Lobo
authors: Mehdi
authors: M
authors: Moradi
authors: Nick
authors: N
authors: Chng
authors: Ehsan
authors: E
authors: Dehghan
authors: Gabor
authors: G
authors: Fichtinger
authors: William J
authors: WJ
authors: Morris
authors: Septimiu E
authors: SE
authors: Salcudean
mesh_terms: D000465:Algorithms; D001918:Brachytherapy / Q000379:methods*; D016000:Cluster Analysis; D005471:Fluoroscopy / Q000379:methods; D006801:Humans; D008297:Male; D015233:Models, Statistical; D009339:Needles; D011471:Prostatic Neoplasms / Q000532:radiotherapy*; D015203:Reproducibility of Results; D014057:Tomography, X-Ray Computed / Q000379:methods