title: Islet transplantation: factors in short-term islet survival.
abstract: Islet transplantation has the potential to cure type 1 diabetes. In recent years, the proportion of patients achieving initial insulin independence has improved, but longer term outcomes remain poor compared to those for whole pancreas transplants. This review article will discuss factors affecting islet yield and viability leading up to transplantation and in the immediate post-transplant period.
authors: Diabetes and Transcription Factors, Garvan Institute of Medical Research, 384 Victoria St, Darlinghurst, NSW, 2010, Australia.
authors: Natasha A
authors: NA
authors: Deters
authors: Rebecca A
authors: RA
authors: Stokes
authors: Jenny E
authors: JE
authors: Gunton
mesh_terms: D000367:Age Factors; D017209:Apoptosis / Q000276:immunology; D003922:Diabetes Mellitus, Type 1 / Q000601:surgery*; D006084:Graft Rejection / Q000517:prevention & control*; D006801:Humans; D000860:Hypoxia / Q000276:immunology; D007249:Inflammation / Q000276:immunology; D016381:Islets of Langerhans Transplantation / Q000276:immunology / Q000379:methods; D016035:Pancreas Transplantation / Q000379:methods; D020858:Tissue and Organ Harvesting / Q000379:methods*; D016896:Treatment Outcome