title: Pathologically confirmed malignant syphilis in an HIV-infected patient.
abstract: We report a case of pathologically confirmed malignant syphilis in an HIV-infected patient. Physical examinations revealed ulceronecrotic skin lesions. Skin biopsies demonstrated syphilis spirochetes on immunohistochemical stain, and syphilis serological titers were positive. Treatment with intravenous penicillin G was begun, and complete resolution of the skin lesions was observed. A rapid plasma reagin titer test performed 3 months after treatment revealed a 4-fold reduction in the titer, indicating successful treatment.
authors: Department of Infectious Diseases, Tokyo Metropolitan Komagome Hospital, Japan. naokiy97@gmail.com
authors: Naoki
authors: N
authors: Yanagisawa
authors: Minoru
authors: M
authors: Ando
authors: Akifumi
authors: A
authors: Imamura
authors: Kumiko
authors: K
authors: Akagi
authors: Shin-ichiro
authors: S
authors: Horiguchi
authors: Akihiko
authors: A
authors: Suganuma
authors: Atsushi
authors: A
authors: Ajisawa
mesh_terms: D000328:Adult; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D008297:Male; D013587:Syphilis / Q000150:complications* / Q000473:pathology*