title: DynaCT evaluation of in-stent restenosis following Wingspan stenting of intracranial stenosis.
abstract: OBJECTIVE
  To describe the use of DynaCT angiographic imaging for the evaluation of Wingspan in-stent restenosis (ISR).
  
  
  METHODS
  Two patients were treated with Wingspan stenting and percutaneous transluminal angioplasty (Patient 1 had treatment of a severe stenosis of the right middle cerebral artery and patient 2 had severe stenosis of the left intracranial internal carotid artery. Both patients developed ISR and were evaluated with high resolution DynaCT angiographic imaging.
  
  
  RESULTS
  DynaCT demonstrated circumferential soft tissue density material distributed within the stent as the cause of the stenosis visualized with conventional angiography.
  
  
  CONCLUSIONS
  These findings support the hypothesis that ISR is caused by neointimal proliferation, rather than vascular re-coil with stent collapse.
authors: Division of Cerebrovascular and Endovascular Neurosurgery, Department of Neurosurgery, Cleveland Clinic, Cleveland, Ohio, USA.
authors: S I
authors: SI
authors: Moskowitz
authors: M E
authors: ME
authors: Kelly
authors: J
authors: J
authors: Haynes
authors: D
authors: D
authors: Fiorella
mesh_terms: D000328:Adult; D000368:Aged; D017130:Angioplasty / Q000592:standards*; D016893:Carotid Stenosis / Q000000981:diagnostic imaging* / Q000628:therapy; D005260:Female; D006801:Humans; D008297:Male; D020768:Middle Cerebral Artery / Q000000981:diagnostic imaging*; D011859:Radiography; D015607:Stents / Q000009:adverse effects*