title: Vitrectomy and internal limiting membrane peeling with and without gas tamponade for myopic foveoschisis.
abstract: OBJECTIVE
  To compare clinical outcomes after vitrectomy and internal limiting membrane (ILM) peeling, with and without gas tamponade, for the treatment of myopic foveoschisis.
  
  
  METHODS
  Retrospective, comparative, interventional case series.
  
  
  METHODS
  In this retrospective clinical study, 17 eyes of 17 consecutive patients underwent vitrectomy and ILM peeling for treatment of myopic foveoschisis. Eyes were divided into 2 groups, those with gas tamponade (n = 9) and those without (n = 8). Gas tamponade was chosen according to the period and surgeon's discretion. The changes of foveal anatomy on preoperative optical coherence tomography (OCT) were not considered in the decision. Main outcome measures were the rate of resolution of myopic foveoschisis measured by OCT, the time interval until resolution of myopic foveoschisis, central foveal thickness, and best-corrected visual acuity (BCVA).
  
  
  RESULTS
  After surgery, OCT showed a resolution of myopic foveoschisis in 8 eyes (88.9%) in the gas-treated group and in 6 eyes (75.0%) in the no-gas group. This difference between the groups was statistically insignificant (P = .576). The mean period until the resolution of myopic foveoschisis was 2.25 months in the gas-treated group and 4.50 months in the no-gas group (P = .011). The mean BCVA improved significantly in both the gas-treated and no-gas groups (P = .011 and P = .017, respectively).
  
  
  CONCLUSIONS
  Vitrectomy and ILM peeling without gas tamponade appears to be as effective in the treatment of myopic foveoschisis as vitrectomy with gas tamponade. However, eyes treated with gas tamponade showed more rapid resolution of myopic foveoschisis.
authors: Department of Ophthalmology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
authors: Kyu Seop
authors: KS
authors: Kim
authors: Seung Bum
authors: SB
authors: Lee
authors: Won Ki
authors: WK
authors: Lee
mesh_terms: D000328:Adult; D000368:Aged; D058452:Axial Length, Eye; D001485:Basement Membrane / Q000601:surgery*; D058450:Endotamponade; D005260:Female; D005466:Fluorocarbons / Q000008:administration & dosage*; D006801:Humans; D008875:Middle Aged; D009216:Myopia / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery*; D041441:Retinoschisis / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery*; D012189:Retrospective Studies; D041623:Tomography, Optical Coherence; D014792:Visual Acuity / Q000502:physiology; D014821:Vitrectomy
chemical_list: D005466:Fluorocarbons; C042852:perflutren