title: MeCP2: phosphorylated locally, acting globally.
abstract: In this issue of Neuron, Greenberg and colleagues revise our understanding of how activity-dependent MeCP2 phosphorylation regulates distinct aspects of brain development and circuit function. The study also suggests a prominent role for MeCP2 in the regulation of global chromatin state in vivo.
authors: Department of Biology and National Center for Behavioral Genomics, Brandeis University, Waltham, MA 02454, USA.
authors: Michael
authors: M
authors: Rutlin
authors: Sacha B
authors: SB
authors: Nelson
mesh_terms: D000818:Animals; D001921:Brain / Q000254:growth & development*; D005106:Exploratory Behavior / Q000502:physiology*; D018507:Gene Expression Regulation, Developmental / Q000502:physiology*; D016678:Genome / Q000502:physiology*; D051783:Methyl-CpG-Binding Protein 2 / Q000235:genetics* / Q000502:physiology*
chemical_list: C497393:Mecp2 protein, mouse; D051783:Methyl-CpG-Binding Protein 2