title: CVD graphene electrochemistry: biologically relevant molecules.
abstract: We investigate the electrochemical properties of CVD grown graphene towards the detection of various biologically prevalent analytes including l-ascorbic acid (AA), dopamine hydrochloride (DA), β-nicotinamide adenine dinucleotide (NADH), uric acid (UA) and epinephrine (EP). We find that the observed electrochemical response of the CVD-graphene towards these select analytes does not originate from the graphene, however, from various other contributions including the presence of 'graphitic islands' on the surface of the CVD-graphene which dominate its electrochemistry. In the systems studied within, it appears at best, CVD-graphene acts akin to that of an edge plane pyrolytic graphite (EPPG) electrode constructed from highly ordered pyrolytic graphite. However, in other cases, the response of the CVD-graphene is worse than that of an EPPG electrode, which is likely due to the low O/C ratio.
authors: Faculty of Science and Engineering, School of Science and the Environment, Division of Chemistry and Environmental Science, Manchester Metropolitan University, Chester Street, Manchester M1 5GD, Lancs, UK.
authors: Dale A C
authors: DA
authors: Brownson
authors: Maria
authors: M
authors: Gómez-Mingot
authors: Craig E
authors: CE
authors: Banks
mesh_terms: D001205:Ascorbic Acid / Q000032:analysis*; D015374:Biosensing Techniques / Q000379:methods*; D004298:Dopamine / Q000032:analysis*; D055664:Electrochemical Techniques / Q000379:methods; D004563:Electrochemistry; D004566:Electrodes; D004837:Epinephrine / Q000032:analysis*; D006108:Graphite / Q000737:chemistry*; D009243:NAD / Q000032:analysis*; D014527:Uric Acid / Q000032:analysis*
chemical_list: D009243:NAD; D014527:Uric Acid; D006108:Graphite; D001205:Ascorbic Acid; D004298:Dopamine; D004837:Epinephrine