title: Chemical composition and antimicrobial activity of essential oil of Achillea cretica L. (Asteraceae) from Turkey.
abstract: Hydrodistilled volatile oil from the aerial parts of Achillea cretica L. (Asteraceae) was analysed by a combination of GC and GC/MS. Seventy-six components were identified, constituting 86.4% of the oil. The main constituents of the essential oil were caryophylladienol-II (13.4%), β-maaliene (6.1%), neo-intermedeol (6.0%), carvone (4.9%), spathulenol (4.5%), palmitic acid (3.3%) and selina-3,11-dien-6α-ol (3.2%). The antimicrobial activity was evaluated by the broth-dilution method on nine microbial strains and showed to be quite strong against the Gram-positive bacteria Staphylococcus aureus and Bacillus cereus. The antibacterial properties of A. cretica justify its use in traditional medicine for the treatment of wounds, contaminated through bacterial infections.
authors: Department of Basic Pharmaceutical Sciences, Division of Analytical Chemistry, Faculty of Pharmacy, İnönü University, 44280 Malatya, Turkey. zkucukbay@inonu.edu.tr
authors: F Zehra
authors: FZ
authors: Küçükbay
authors: Ebru
authors: E
authors: Kuyumcu
authors: Tuçe
authors: T
authors: Bilenler
authors: Bayram
authors: B
authors: Yıldız
mesh_terms: D031162:Achillea / Q000737:chemistry*; D000890:Anti-Infective Agents / Q000737:chemistry* / Q000494:pharmacology*; D001409:Bacillus cereus / Q000187:drug effects; D008401:Gas Chromatography-Mass Spectrometry; D008826:Microbial Sensitivity Tests; D009822:Oils, Volatile / Q000737:chemistry* / Q000494:pharmacology*; D013211:Staphylococcus aureus / Q000187:drug effects; D014421:Turkey
chemical_list: D000890:Anti-Infective Agents; D009822:Oils, Volatile