title: Ultrasensitive diagnosis for an anthrax-protective antigen based on a polyvalent directed peptide polymer coupled to zinc oxide nanorods.
abstract: A flexible poly-D-lysine polymer conjugated with different target-binding peptides is demonstrated with an ultralow concentration detection limit compared to those of other conventional detection systems. This polyvalent directed peptide polymer (PDPP) exhibits increased binding affinity and detects anthrax protective antigen at low levels using a well-known zinc oxide nanorod detection system.
authors: Department of Chemistry, Hanyang University, Seoul, Korea.
authors: Hye-Yeon
authors: HY
authors: Park
authors: Vinayakumar
authors: V
authors: Gedi
authors: Joungmok
authors: J
authors: Kim
authors: Hae-Chul
authors: HC
authors: Park
authors: Sung-Hwan
authors: SH
authors: Han
authors: Moon-Young
authors: MY
authors: Yoon
mesh_terms: D000942:Antigens, Bacterial / Q000032:analysis* / Q000378:metabolism; D001427:Bacterial Toxins / Q000032:analysis* / Q000378:metabolism; D015374:Biosensing Techniques / Q000379:methods*; D043942:Nanotubes / Q000737:chemistry*; D010455:Peptides / Q000737:chemistry* / Q000378:metabolism; D015034:Zinc Oxide / Q000737:chemistry*
chemical_list: D000942:Antigens, Bacterial; D001427:Bacterial Toxins; D010455:Peptides; C030325:anthrax toxin; D015034:Zinc Oxide