title: Hydroa vacciniforme-like Epstein-Barr virus-associated lymphoproliferative disease: a case report.
abstract: We report a case of hydroa vacciniforme-like skin eruptions with chronic active Epstein-Barr virus infection in a 16-year-old boy. The patient had repeated episodes of vesiculo-necrotic eruptions on the face, trunk, and extremities for 13 years. General symptoms included fever, splenomegaly, and abnormal liver function. Histopathological examination of skin biopsy specimen demonstrated dense infiltration of lymphocytes, histocytes, and some neutrophils and plasma cells in the dermis. Immunohistochemical stain revealed that the lymphocytes were positive for T cell and B cell markers. Epstein-Barr virus infection studies and systemic presentation confirmed the diagnosis.
authors: Department of Dermatology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
authors: Yueping
authors: Y
authors: Zeng
authors: Lanqin
authors: L
authors: Fu
authors: Hongzhong
authors: H
authors: Jin
authors: Qiuning
authors: Q
authors: Sun
authors: Baoxi
authors: B
authors: Wang
mesh_terms: D000293:Adolescent; D001706:Biopsy; D020031:Epstein-Barr Virus Infections / Q000150:complications*; D006801:Humans; D006837:Hydroa Vacciniforme / Q000150:complications* / Q000473:pathology / Q000821:virology*; D008232:Lymphoproliferative Disorders / Q000150:complications* / Q000821:virology*; D008297:Male; D012867:Skin / Q000473:pathology