title: N-Bromosuccinimide promoted one-pot synthesis of guanidine: scope and mechanism.
abstract: A novel electrophilic one-pot guanidine synthesis has been developed using an olefin, a cyanimide, an amine, and N-bromosuccinimide. A number of guanidine derivatives were prepared with good to excellent yields. An rTRTVI precursor was also prepared based on this useful process.
authors: 3 Science Drive 3, Department of Chemistry, National University of Singapore, Singapore 117543.
authors: Ling
authors: L
authors: Zhou
authors: Jie
authors: J
authors: Chen
authors: Jing
authors: J
authors: Zhou
authors: Ying-Yeung
authors: YY
authors: Yeung
mesh_terms: D000475:Alkenes / Q000737:chemistry; D000588:Amines / Q000737:chemistry; D001974:Bromosuccinimide / Q000737:chemistry*; D003485:Cyanates / Q000737:chemistry; D019791:Guanidine / Q000031:analogs & derivatives / Q000138:chemical synthesis*; D015394:Molecular Structure
chemical_list: D000475:Alkenes; D000588:Amines; D003485:Cyanates; D019791:Guanidine; D001974:Bromosuccinimide