title: Deep brain stimulation in the treatment of chorea.
abstract: Deep brain stimulation has been used as a means of reducing dyskinesias in various conditions, including Parkinson's disease and dystonia for many years. Recently, owing to the clinical similarities between L-dopa induced dyskinesia and chorea, deep brain stimulation has now been implemented as a novel treatment method in both Huntington's disease and neuroacanthocytosis, and a paucity of case studies exist reporting its efficacy. This review will summarize the case studies of deep brain stimulation in both Huntington's disease and neuroacanthocytosis, and discuss the possible implications and limitations associated with these reports. As both these disorders are often refractory to medication and difficult to treat, deep brain stimulation may be a useful treatment option in the future.
authors: Sobell Department of Motor Neuroscience, UCL Institute of Neurology, Queen Square, London, WC1N 3BG, UK.
authors: Thomas C
authors: TC
authors: Edwards
authors: Ludvic
authors: L
authors: Zrinzo
authors: Patricia
authors: P
authors: Limousin
authors: Tom
authors: T
authors: Foltynie
mesh_terms: D002819:Chorea / Q000628:therapy*; D016206:Databases, Bibliographic / Q000706:statistics & numerical data; D046690:Deep Brain Stimulation / Q000379:methods*; D006801:Humans