title: Extensively drug-resistant tuberculosis case in the Thames Valley, UK and public health interventions.
abstract: This study describes the first case of extensively drug-resistant tuberculosis (XDR-TB) in the Thames Valley and South East Region and discuss the public health implications, highlighting the need to integrate current epidemiological knowledge with clinical expertise in order to diagnose drug-resistant tuberculosis (TB) early. The management of the XDR-TB patients is challenging with few treatment options, expensive therapy, side effects of drugs and a longer course of the treatment.
authors: Thames Valley Health Protection Unit, Chilton, Oxfordshire, UK. muhammad.abid@hpa.org.uk
authors: Muhammad
authors: M
authors: Abid
authors: Noel
authors: N
authors: McCarthy
authors: Luisa
authors: L
authors: Saldaña
authors: Tracey
authors: T
authors: Langham
authors: Anne
authors: A
authors: McGown
authors: Christopher
authors: C
authors: Conlon
authors: Pablo
authors: P
authors: de Vena Franks
mesh_terms: D000328:Adult; D000995:Antitubercular Agents / Q000494:pharmacology; D016358:Contact Tracing / Q000379:methods*; D024901:Drug Resistance, Multiple, Bacterial; D054908:Extensively Drug-Resistant Tuberculosis / Q000175:diagnosis* / Q000453:epidemiology / Q000382:microbiology / Q000517:prevention & control; D006801:Humans; D008403:Mass Screening / Q000379:methods*; D009169:Mycobacterium tuberculosis / Q000145:classification / Q000187:drug effects / Q000235:genetics*; D011159:Population Surveillance; D011634:Public Health; D006113:United Kingdom / Q000453:epidemiology; D055815:Young Adult
chemical_list: D000995:Antitubercular Agents