title: Leptomeningeal carcinomatosis from ovarian cancer.
abstract: Ovarian cancer is the most common cause of mortality among women with gynecologic malignancies and the fifth leading cause of death in all women. It usually spreads locally; hematogenous dissemination is rare, most often involving the liver and lungs. Cerebral metastases are reported in less than 2% of cases and tend to localize to the parenchyma, usually in the cerebrum. Leptomeningeal involvement is exceptionally rare. We report a case of a woman with metastatic ovarian cancer who developed leptomeningeal carcinomatosis while receiving systemic chemotherapy. We also provide an extensive review of the existing literature on neoplastic meningitis from ovarian cancer.
authors: Columbia University College of Physicians and Surgeons, 2012 630 West 168th St, New York, NY 10032, USA. ecm2137@columbia.edu
authors: Eliza
authors: E
authors: Miller
authors: Irene
authors: I
authors: Dy
authors: Thomas
authors: T
authors: Herzog
mesh_terms: D005260:Female; D006801:Humans; D055756:Meningeal Carcinomatosis / Q000556:secondary*; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000473:pathology*