title: Anatomic dependency of phase shifts in the cerebral venous system of neonates at susceptibility-weighted MRI.
abstract: OBJECTIVE
  To assess the anatomic variation and age-related changes of phase shifts in the neonatal cerebral venous system at susceptibility-weighted imaging (SWI).
  
  
  METHODS
  Thirty-five neonates who had undergone SWI and who did not have any intracranial or systemic abnormalities were retrospectively assessed. Phase shifts in the veins in the deep gray matter and in the cortical veins in the frontal, rolandic, and parietal areas were measured and compared. Correlations between phase ratio (ratio of the phase shift in the vein in the deep gray matter to that in the cortical veins) and gestational age at birth, gestational age at magnetic resonance imaging (MRI), and age after birth were assessed.
  
  
  RESULTS
  Phase shift in the veins in the deep gray matter was significantly higher than those in the cortical veins (P < 0.01). Among the cortical veins, the venous phase shift in the rolandic area was significantly higher than those in the frontal and parietal areas (P < 0.01). There was a negative correlation between the phase ratio and the gestational age at MRI (Spearman ρ = -0.35, P = 0.04).
  
  
  CONCLUSIONS
  An anatomical variation in phase shifts was identified in the neonatal venous system. The observed reduction in phase shift differences between the veins in the deep gray matter and those in the cortex as gestational age at MRI increased may reflect brain development.
authors: Department of Radiology, Kanagawa Children's Medical Center, Yokohama, Japan. tniwa@kcmc.jp
authors: Tetsu
authors: T
authors: Niwa
authors: Noriko
authors: N
authors: Aida
authors: Hiroshi
authors: H
authors: Kawaguchi
authors: Takayuki
authors: T
authors: Obata
authors: Thomas C
authors: TC
authors: Kwee
authors: Yasuhiko
authors: Y
authors: Tachibana
authors: Jun
authors: J
authors: Shibasaki
authors: Taro
authors: T
authors: Takahara
mesh_terms: D001921:Brain / Q000502:physiology; D002550:Cerebral Veins / Q000033:anatomy & histology* / Q000473:pathology*; D002560:Cerebrovascular Circulation; D005865:Gestational Age; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods; D007231:Infant, Newborn; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008953:Models, Anatomic; D015233:Models, Statistical