title: Prospective assessment of transient cocaine-induced psychotic symptoms in a clinical setting.
abstract: Cocaine use is associated with the occurrence of transient psychotic symptoms. Sixteen poly-substance abusers already in treatment, who were diagnosed with crack dependence, were assessed twice: at baseline and after 3 weeks of medical management specifically aimed at cocaine abstinence. The psychotic symptoms were assessed with the French version of the Scale for Assessment of Positive Symptoms-Cocaine-Induced Psychosis (SAPS-CIP). There was a decrease of both cocaine intake and psychotic symptoms at week 3 (Wilcoxon's Z, p < .001 and .028, respectively). Furthermore, there was a significant correlation between psychotic symptoms and dose reduction (r(2) = .49, Spearman's ρ= .613, p < .012).
authors: Neuropsychopharmacologie des Addictions, INSERM U, CNRS UMR, Université PRES Sorbonne-Paris Cité, Paris, France. florence.vorspan@lrb.aphp.fr
authors: Florence
authors: F
authors: Vorspan
authors: Vanessa
authors: V
authors: Bloch
authors: Georges
authors: G
authors: Brousse
authors: Laetitia
authors: L
authors: Bellais
authors: Julien
authors: J
authors: Gascon
authors: Jean-Pierre
authors: JP
authors: Lépine
mesh_terms: D000328:Adult; D019970:Cocaine-Related Disorders / Q000150:complications / Q000523:psychology*; D016578:Crack Cocaine / Q000008:administration & dosage / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D011446:Prospective Studies; D011569:Psychiatric Status Rating Scales / Q000706:statistics & numerical data; D011605:Psychoses, Substance-Induced / Q000150:complications / Q000523:psychology*; D012651:Self Medication / Q000706:statistics & numerical data*
chemical_list: D016578:Crack Cocaine