title: Chronic inflammatory lumbosacral polyradiculopathy: a regional variant of CIDP.
abstract: Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) affects various components and segments of the peripheral nervous system differently, and thus there can be phenotypic heterogeneity. We report a 47-year-old woman with chronic sensory disturbances and proximal weakness limited to the legs. Motor and sensory nerve conduction studies were normal. Somatosensory evoked potentials and imaging indicated a demyelinating process involving the lumbosacral roots. The patient responded favorably to IVIg. Although she did not fulfill the diagnostic criteria for CIDP we believe this patient represents a restricted regional CIDP variant.
authors: Neurocenter of Southern Switzerland (EOC), Ospedale Civico, EOC Via Tesserete 46, 6900 Lugano, Switzerland. christina.caporale@eoc.ch
authors: Christina M
authors: CM
authors: Caporale
authors: Claudio
authors: C
authors: Staedler
authors: Claudio
authors: C
authors: Gobbi
authors: Claudio L
authors: CL
authors: Bassetti
authors: Antonino
authors: A
authors: Uncini
mesh_terms: D005260:Female; D014644:Genetic Variation / Q000235:genetics*; D006801:Humans; D008161:Lumbosacral Region / Q000503:physiopathology*; D008875:Middle Aged; D020277:Polyradiculoneuropathy, Chronic Inflammatory Demyelinating / Q000175:diagnosis* / Q000235:genetics* / Q000503:physiopathology