title: How HIV takes advantage of the cytoskeleton in entry and replication.
abstract: The host cell cytoskeleton plays a key role in the life cycle of viral pathogens whose propagation depends on mandatory intracellular steps. Accordingly, also the human immunodeficiency virus type 1 (HIV-1) has evolved strategies to exploit and modulate in particular the actin cytoskeleton for its purposes. This review will recapitulate recent findings on how HIV-1 hijacks the cytoskeleton to facilitate entry into, transport within and egress from host cells as well as to commandeer communication of infected with uninfected bystander cells.
authors: Department of Infectious Diseases, Virology, University Hospital Heidelberg, Heidelberg, Germany. bettina.stolp@med.uni-heidelberg.de
authors: Bettina
authors: B
authors: Stolp
authors: Oliver T
authors: OT
authors: Fackler
mesh_terms: D000818:Animals; D003599:Cytoskeleton / Q000378:metabolism / Q000821:virology*; D006678:HIV / Q000235:genetics / Q000502:physiology*; D015658:HIV Infections / Q000378:metabolism / Q000821:virology*; D006801:Humans; D053586:Virus Internalization; D014779:Virus Replication