title: The action mechanisms of plant cryptochromes.
abstract: Cryptochromes (CRY) are blue-light receptors that mediate various light responses in plants. The photoexcited CRY molecules undergo several biophysical and biochemical changes, including electron transfer, phosphorylation and ubiquitination, resulting in conformational changes to propagate light signals. Two modes of CRY signal transduction have recently been discovered: the cryptochrome-interacting basic-helix-loop-helix 1 (CIB)-dependent CRY2 regulation of transcription; and the SUPPRESSOR OF PHYA1/CONSTITUTIVELY PHOTOMORPHOGENIC1 (SPA1/COP1)-dependent cryptochrome regulation of proteolysis. Both CRY signaling pathways rely on blue light-dependent interactions between the CRY photoreceptor and its signaling proteins to modulate gene expression changes in response to blue light, leading to altered developmental programs in plants.
authors: Department of Molecular, Cell & Developmental Biology, University of California, Los Angeles, CA 90095, USA.
authors: Hongtao
authors: H
authors: Liu
authors: Bin
authors: B
authors: Liu
authors: Chenxi
authors: C
authors: Zhao
authors: Michael
authors: M
authors: Pepper
authors: Chentao
authors: C
authors: Lin
mesh_terms: D017360:Arabidopsis / Q000378:metabolism / Q000502:physiology*; D056931:Cryptochromes / Q000378:metabolism / Q000502:physiology*; D055519:Photoreceptors, Plant / Q000502:physiology; D015398:Signal Transduction
chemical_list: D056931:Cryptochromes; D055519:Photoreceptors, Plant