title: Skull base chordomas.
abstract: Skull base chordomas are rare midline malignancies of clival origin that represent one of the most challenging skull base tumors to treat, given their location, invasiveness, potential extension around vital neurovascular structures, and high recurrence rate. Total tumor resection is the mainstay of treatment. The combination of surgery and postoperative irradiation appears to provide the best outcome.
authors: Department of Neurological Surgery, University of Pittsburgh School of Medicine, 200 Lothrop Street, PUH 400, Pittsburgh, PA 15213, USA.
authors: Maria
authors: M
authors: Koutourousiou
authors: Carl H
authors: CH
authors: Snyderman
authors: Juan
authors: J
authors: Fernandez-Miranda
authors: Paul A
authors: PA
authors: Gardner
mesh_terms: D002817:Chordoma / Q000175:diagnosis / Q000601:surgery*; D004724:Endoscopy / Q000009:adverse effects / Q000379:methods; D006801:Humans; D008279:Magnetic Resonance Imaging; D011183:Postoperative Complications; D019292:Skull Base Neoplasms / Q000175:diagnosis / Q000601:surgery*