title: Relationship between macular ganglion cell complex parameters and visual field parameters after tumor resection in chiasmal compression.
abstract: OBJECTIVE
  To evaluate the relationship between macular ganglion cell complex (GCC) parameters and visual field (VF) parameters in chiasmal compression and the potential for GCC parameters in order to predict the short-term postsurgical VF.
  
  
  METHODS
  Twenty-three eyes of 12 patients with chiasmal compression and 33 control eyes were studied. All patients underwent transsphenoidal tumor resection. Before surgery a 3D scan of the macula was taken using spectral-domain optical coherence tomography. All patients underwent Humphrey 24-2 VF testing after surgery. Spearman's rank correlation coefficients were used to evaluate the relationship between the GCC parameters and VF parameters [mean deviation (MD), pattern standard deviation]. Coefficients of determination (R2) were calculated using linear regression.
  
  
  RESULTS
  Average thickness in the patients was significantly thinner than that of controls. Average thickness, global loss volume and focal loss volume (FLV) significantly correlated with the MD. We observed the greatest R2 between FLV and MD.
  
  
  CONCLUSIONS
  Examining the macular GCC was useful for evaluating structural damage in patients with chiasmal compression. Preoperative GCC parameters, especially FLV, may be useful in predicting visual function following surgical decompression of chiasmal compression.
authors: Department of Ophthalmology and Visual Science, Kanazawa University Graduate School of Medical Science, 13-1 Takara-machi, Kanazawa 920-8641, Japan. eyeshin@med.kanazawa-u.ac.jp
authors: Shinji
authors: S
authors: Ohkubo
authors: Tomomi
authors: T
authors: Higashide
authors: Hisashi
authors: H
authors: Takeda
authors: Eiji
authors: E
authors: Murotani
authors: Yasuhiko
authors: Y
authors: Hayashi
authors: Kazuhisa
authors: K
authors: Sugiyama
mesh_terms: D000236:Adenoma / Q000150:complications / Q000601:surgery; D000328:Adult; D000368:Aged; D003560:Cysts / Q000150:complications / Q000601:surgery; D019299:Decompression, Surgical; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009408:Nerve Compression Syndromes / Q000209:etiology / Q000503:physiopathology*; D009412:Nerve Fibers / Q000473:pathology*; D009897:Optic Chiasm / Q000503:physiopathology*; D010911:Pituitary Neoplasms / Q000150:complications / Q000601:surgery*; D012165:Retinal Ganglion Cells / Q000473:pathology*; D041623:Tomography, Optical Coherence; D058609:Visual Field Tests; D014794:Visual Fields / Q000502:physiology*; D055815:Young Adult