title: [Administration of dalteparin in reconstructive vascular surgery].
abstract: The article contains a review of the literature regarding the use of low-molecular-weight heparins (LMWHs) exemplified by dalteparin in the hitherto insufficiently explored area of their implementation, i. e., during the intraoperative period in patients suff ering from atherothrombosis. Presented herein is analysis of alterations in the parameters of the plasmatic and thrombocytic links of haemostatis during intraoperative administration of various molecular-weight fractions of heparin. The obtained findings make it possible to conclude that LMWHs do off er certain advantages when used during surgical interventions in patients with atherosclerotic lesions of the arterial bed.
authors: A V
authors: AV
authors: Pokrovskiĭ
authors: V N
authors: VN
authors: Gontarenko
authors: M I
authors: MI
authors: Titova
mesh_terms: D000925:Anticoagulants / Q000008:administration & dosage / Q000009:adverse effects / Q000493:pharmacokinetics; D001157:Arterial Occlusive Diseases / Q000097:blood / Q000473:pathology / Q000517:prevention & control*; D001158:Arteries / Q000473:pathology*; D001777:Blood Coagulation / Q000187:drug effects*; D001779:Blood Coagulation Factors / Q000378:metabolism; D001780:Blood Coagulation Tests; D002986:Clinical Trials as Topic; D017985:Dalteparin / Q000008:administration & dosage / Q000009:adverse effects / Q000493:pharmacokinetics; D016903:Drug Monitoring; D006488:Hemostasis, Surgical / Q000379:methods; D006493:Heparin / Q000008:administration & dosage / Q000009:adverse effects / Q000493:pharmacokinetics; D006801:Humans; D007431:Intraoperative Complications / Q000097:blood / Q000473:pathology / Q000517:prevention & control*; D018579:Patient Selection; D018570:Risk Assessment; D013927:Thrombosis / Q000097:blood / Q000473:pathology / Q000517:prevention & control*; D014656:Vascular Surgical Procedures / Q000009:adverse effects
chemical_list: D000925:Anticoagulants; D001779:Blood Coagulation Factors; D006493:Heparin; D017985:Dalteparin