title: Nucleophilic ortho allylation of aryl and heteroaryl sulfoxides.
abstract: Aryl and heteroaryl sulfoxides undergo ortho allylation upon treatment with Tf(2)O and allylsilanes. The method complements the use of sulfoxides to direct ortho-metalation and reaction with electrophiles as it allows allylic carbon nucleophiles to be added ortho to the directing group in a metal-free process. The versatile sulfide adducts can be selectively manipulated using various methods including Kumada-Corriu cross-coupling of the organosulfanyl group.
authors: School of Chemistry, University of Manchester, Oxford Road, Manchester, M13 9PL, UK.
authors: Andrew J
authors: AJ
authors: Eberhart
authors: Jason E
authors: JE
authors: Imbriglio
authors: David J
authors: DJ
authors: Procter
mesh_terms: D002384:Catalysis; D015394:Molecular Structure; D013454:Sulfoxides / Q000737:chemistry*
chemical_list: D013454:Sulfoxides