title: Magnetic-fluorescent nanohybrids of carbon nanotubes coated with Eu, Gd co-doped LaF3 as a multimodal imaging probe.
abstract: Multifunctional magnetic-fluorescent nanohybrids were successfully fabricated by a facile layer-by-layer (LBL) self-assembly of in situ generated Eu, Gd co-doped LaF(3) nanocrystals (LaF(3):Eu:Gd) on the surface of multi-walled carbon nanotubes (MWNTs). Photoluminescence (PL) quenching occurred when LaF(3):Eu:Gd nanoparticles were directly coated on the surface of MWNTs. By growth of a SiO(2) shell spacer between MWNTs and LaF(3):Eu:Gd nanocrystals, we circumvented the PL quenching and achieved the magnetic-fluorescent MWNTs. Moreover, the nanohybrids showed powerful T(1) and T(2)-weighted magnetic resonance imaging (MRI) signal in water and could be used as MRI contrast agents. As a result, the nanohybrids can be expected to act as a promising multimodal MRI/optical imaging probe.
authors: State Key Lab of Silicon Materials, Department of Materials Science and Engineering, Zhejiang University, Hangzhou 310027, People's Republic of China. inanochen@tongji.edu.cn
authors: Bingdi
authors: B
authors: Chen
authors: Hui
authors: H
authors: Zhang
authors: Ning
authors: N
authors: Du
authors: Bo
authors: B
authors: Zhang
authors: Yulian
authors: Y
authors: Wu
authors: Donglu
authors: D
authors: Shi
authors: Deren
authors: D
authors: Yang
mesh_terms: D003287:Contrast Media / Q000737:chemistry*; D005063:Europium / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000737:chemistry; D005459:Fluorides / Q000737:chemistry*; D005682:Gadolinium / Q000737:chemistry*; D007811:Lanthanum / Q000737:chemistry*; D008279:Magnetic Resonance Imaging / Q000379:methods; D059346:Magnets / Q000737:chemistry; D053758:Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D037742:Nanotubes, Carbon / Q000737:chemistry* / Q000648:ultrastructure
chemical_list: D003287:Contrast Media; D005456:Fluorescent Dyes; D037742:Nanotubes, Carbon; C083668:lanthanum trifluoride; D005063:Europium; D007811:Lanthanum; D005682:Gadolinium; D005459:Fluorides