title: Aplasia cutis congenita and other anomalies associated with methimazole exposure during pregnancy.
abstract: Aplasia cutis congenita (ACC) is a congenital defect consisting of a circumscribed absence of skin that usually involves the scalp. The etiology is uncertain, and several teratogenic agents such as methimazole have been involved. We report two cases of ACC and other anomalies in newborns exposed to methimazole during pregnancy.
authors: Department of Dermatology, Hospital Universitario de Canarias, University of La Laguna (Canary Islands), Spain.
authors: Cristina
authors: C
authors: Rodríguez-García
authors: Department of Dermatology, Hospital Universitario de Canarias, University of La Laguna (Canary Islands), Spain.
authors: Sorahaya
authors: S
authors: González-Hernández
authors: Department of Dermatology, Hospital del Niño Jesús, Madrid, Spain.
authors: Angela
authors: A
authors: Hernández-Martín
authors: Department of Dermatology, Hospital Universitario de Canarias, University of La Laguna (Canary Islands), Spain.
authors: Nuria
authors: N
authors: Pérez-Robayna
authors: Department of Dermatology, Hospital Universitario de Canarias, University of La Laguna (Canary Islands), Spain.
authors: Rosalba
authors: R
authors: Sánchez
authors: Department of Dermatology, Hospital del Niño Jesús, Madrid, Spain.
authors: Antonio
authors: A
authors: Torrelo
mesh_terms: D000328:Adult; D013956:Antithyroid Agents / Q000009:adverse effects*; D004476:Ectodermal Dysplasia / Q000139:chemically induced*; D005260:Female; D006111:Graves Disease / Q000188:drug therapy*; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D008713:Methimazole / Q000009:adverse effects*; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects / Q000139:chemically induced*; D011441:Propylthiouracil / Q000009:adverse effects; D012535:Scalp / Q000002:abnormalities
chemical_list: D013956:Antithyroid Agents; D008713:Methimazole; D011441:Propylthiouracil