title: Tinea corporis due to Trichophyton rubrum in a woman and Tinea capitis in her 15-day-old baby: molecular evidence of vertical transmission.
abstract: We report a case of a 40-year-old Caucasian woman who came under our observation with a 7-year history of a chronic erythematous scaly dermatitis, diagnosed as psoriasis, involving gluteal area and thighs, and treated with topical steroids without benefit. During pregnancy, a progressive worsening of her condition and an extension of cutaneous lesions were observed. Her newborn, a 15-day-old girl, presented a similar scaly and squamous lesion on her scalp. Mycological examination was positive for Trichophyton rubrum in both cases, and random amplified polymorphic DNA analysis confirmed the isogenicity of the two isolates. We performed a diagnosis of T. rubrum                         tinea corporis and tinea capitis. The case we describe illustrates an unusual clinical presentation of tinea corporis with remarkable extension of cutaneous lesions due to the diagnostic delay and the continuous use of local steroids, together with a rare tinea capitis in the newborn. Our experience highlights the possibility of mother-child transmission and the importance of an early diagnosis.
authors: Dermatologic Department, San Paolo Hospital, University of Milan, Milan, Italy. elisabetta.mapelli@hotmail.it
authors: E T M
authors: ET
authors: Mapelli
authors: E
authors: E
authors: Borghi
authors: A
authors: A
authors: Cerri
authors: R
authors: R
authors: Sciota
authors: G
authors: G
authors: Morace
authors: S
authors: S
authors: Menni
mesh_terms: D000328:Adult; D000935:Antifungal Agents / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D018445:Infectious Disease Transmission, Vertical; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000382:microbiology*; D014005:Tinea / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology / Q000635:transmission*; D014006:Tinea Capitis / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology / Q000635:transmission*; D014249:Trichophyton / Q000235:genetics / Q000302:isolation & purification* / Q000502:physiology
chemical_list: D000935:Antifungal Agents