title: Stem cells: keeping BMP signaling local.
abstract: In stem cell niches, the spatial extent of growth factor signaling needs to be tightly controlled. A new study on the Drosophila testicular germline stem cell niche has revealed that BMP signaling is locally activated through linkage to adherens junctions.
authors: Stowers Institute for Medical Research, Kansas City, MO 64110, USA.
authors: Xing
authors: X
authors: Ma
authors: Ting
authors: T
authors: Xie
mesh_terms: D022005:Adherens Junctions / Q000235:genetics / Q000378:metabolism; D000818:Animals; D019485:Bone Morphogenetic Proteins / Q000378:metabolism*; D004330:Drosophila / Q000166:cytology* / Q000235:genetics / Q000378:metabolism*; D029721:Drosophila Proteins / Q000235:genetics / Q000378:metabolism*; D005854:Germ Cells / Q000166:cytology / Q000378:metabolism; D008297:Male; D017346:Protein Serine-Threonine Kinases / Q000235:genetics / Q000378:metabolism; D011956:Receptors, Cell Surface / Q000235:genetics / Q000378:metabolism*; D015398:Signal Transduction; D055153:Stem Cell Niche; D013234:Stem Cells / Q000166:cytology / Q000378:metabolism; D013737:Testis / Q000166:cytology / Q000378:metabolism
chemical_list: D019485:Bone Morphogenetic Proteins; D029721:Drosophila Proteins; D011956:Receptors, Cell Surface; C090169:tkv protein, Drosophila; D017346:Protein Serine-Threonine Kinases