title: Designing the biocompatibility of biohybrids.
abstract: Biohybrid has been used as a fashionable term in scientific publications during the past years to describe a functional unit consisting of a bioactive and a structural component. The bioactive part of the biohybrid could consist of cells or bioactive molecules, while the structural part is of biological or non-biological origin. Biohybrids are currently used as implants and transplants in regenerative medicine or in vitro applications such as assays, biosensors or bioreactors. However, a clear definition of a biohybrid has not been given yet. This chapter reviews the current applications of biohybrids and identifies the challenges of biohybrids in in vivo applications. A classification of biohybrids according to their functional use and application is provided.
authors: Laboratory for Biomechanics and Biomaterials, Orthopaedic Clinic, Hannover Medical School, Anna-von-Borries-Straβe 1-7, 30625, Hannover, Germany, witte.frank@mh-hannover.de.
authors: Frank
authors: F
authors: Witte
authors: Ivonne
authors: I
authors: Bartsch
authors: Elmar
authors: E
authors: Willbold
mesh_terms: D001672:Biocompatible Materials / Q000138:chemical synthesis*; D001688:Biological Products / Q000737:chemistry*; D019736:Prostheses and Implants; D011474:Prosthesis Design; D013499:Surface Properties; D023822:Tissue Engineering / Q000379:methods*
chemical_list: D001672:Biocompatible Materials; D001688:Biological Products