title: Transforming terpene-derived aldehydes into 1,2-epoxides via asymmetric α-chlorination: subsequent epoxide opening with carbon nucleophiles.
abstract: Merging Jørgensen's and MacMillan's organocatalytic aldehyde chlorinations enables the synthesis of chiral vinylcyclopropanes and (-)-cis-aerangis lactone via terpene-derived 1,2-epoxides.
authors: TU Dortmund University, Otto-Hahn-Straße 6, D-44227 Dortmund, Germany.
authors: Philipp
authors: P
authors: Winter
authors: Jörg
authors: J
authors: Swatschek
authors: Matthieu
authors: M
authors: Willot
authors: Lea
authors: L
authors: Radtke
authors: Tobias
authors: T
authors: Olbrisch
authors: Andreas
authors: A
authors: Schäfer
authors: Mathias
authors: M
authors: Christmann
mesh_terms: D000447:Aldehydes / Q000737:chemistry*; D003521:Cyclopropanes / Q000737:chemistry; D004852:Epoxy Compounds / Q000737:chemistry*; D054879:Halogenation; D007783:Lactones / Q000737:chemistry; D013729:Terpenes / Q000737:chemistry*; D014753:Vinyl Compounds / Q000737:chemistry
chemical_list: D000447:Aldehydes; D003521:Cyclopropanes; D004852:Epoxy Compounds; D007783:Lactones; D013729:Terpenes; D014753:Vinyl Compounds