title: Physical activity and cognitive function in multiple sclerosis.
abstract: Cognitive impairment is prevalent, disabling, and poorly managed in persons with multiple sclerosis (MS). This cross-sectional study examined the associations among physical activity, cognitive processing speed, and learning and memory in 33 persons with MS who underwent neuropsychological assessments and wore a physical activity monitor for 7 days. Cognitive impairment was greatest in cognitive processing speed. Physical activity was significantly correlated with cognitive processing speed (pr = .35), but not learning and memory (pr = .20), after controlling for sex, age, and education. Researchers should examine exercise training and physical activity effects on cognitive performance, particularly processing speed, in MS.
authors: Department of Kinesiology and Community Health, University of Illinois at Urbana-Champaign, USA.
authors: Robert W
authors: RW
authors: Motl
authors: Eduard
authors: E
authors: Gappmaier
authors: Kathryn
authors: K
authors: Nelson
authors: Ralph H B
authors: RH
authors: Benedict
mesh_terms: D056044:Actigraphy / Q000295:instrumentation; D000328:Adult; D000368:Aged; D003071:Cognition; D003072:Cognition Disorders; D003430:Cross-Sectional Studies; D015444:Exercise / Q000523:psychology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000523:psychology*; D011930:Reaction Time; D014589:Utah