title: Iron-catalyzed oxidative monoarylation of primary amines with organozinc reagents.
abstract: The reaction of a primary zinc amide with a diorganozinc reagent gives a secondary amine in the presence of Fe(acac)(3) as a catalyst and 1,2-dichloroisobutane (DCIB) as an oxidant. Halogen groups such as F, Cl, Br, and I are tolerated well. The dichloride oxidant and heat are essential to achieve the C-N bond formation presumably from a catalytic iron intermediate species bearing aryl and amido groups.
authors: Department of Chemistry, School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033.
authors: Yuki
authors: Y
authors: Nakamura
authors: Laurean
authors: L
authors: Ilies
authors: Eiichi
authors: E
authors: Nakamura