title: [Comorbidity, discapacity and mortality in patients with multiple conditions and chronic obstructive pulmonary disease].
abstract: OBJECTIVE
  To determine the association between different comorbidities and other clinical conditions with mortality in patients with multiple diseases (PMD) suffering from chronic obstructive pulmonary disease (COPD).
  
  
  METHODS
  Patients with COPD and PMD criteria were included in an observational, prospective and multicentrer study. Data on age, gender, Charlson index, Barthel index, Lawton-Brody index, Pfeiffer test, sociofamilial Gijon scale, education level, hospitalizations during the previous 3 and 12 months and survival at one year were collected. The relationship between the variables and mortality were established by means of a univariate analysis and logistic regression model.
  
  
  RESULTS
  A total of 688 PMD with COPD and mean age of 77.9 years were included. The mean score one the Charlson index was 3.99 (2.07). The most frequent comorbidities were heart failure (59%), diabetes (48%), myocardial infarction (29%), moderate kidney failure (22%), cerebrovascular disease (19%), hypertension (71%), anemia (62%), atrial fibrillation (34%), dyslipidemia (28%) and obesity (21%). A total of 26% of patients were dependent for activities of daily living, 47% needed a caregiver and 54% were at risk of having social problems. At one year, 258 patients (37%) had died. The Charlson index, dependency for activities of daily living and anemia were associated with mortality and hypertension and capacity for reading and writing were associated with survival.
  
  
  CONCLUSIONS
  Comorbidity and discapacity are two prognostic factors in COPD patients.
authors: Servicio de Medicina Interna, Hospital Royo Villanova, Zaragoza, España. jdiez@aragon.es
authors: J
authors: J
authors: Díez Manglano
authors: M
authors: M
authors: Bernabeu-Wittel
authors: A
authors: A
authors: Escalera-Zalvide
authors: M
authors: M
authors: Sánchez-Ledesma
authors: A
authors: A
authors: Mora-Rufete
authors: D
authors: D
authors: Nieto-Martín
authors: J
authors: J
authors: Barbé Gil-Ortega
authors: L
authors: L
authors: Moreno-Gaviño
mesh_terms: D000203:Activities of Daily Living; D000368:Aged; D000369:Aged, 80 and over; D015897:Comorbidity; D005260:Female; D006305:Health Status Indicators; D006760:Hospitalization / Q000706:statistics & numerical data; D006801:Humans; D016015:Logistic Models; D008297:Male; D011379:Prognosis; D011446:Prospective Studies; D029424:Pulmonary Disease, Chronic Obstructive / Q000453:epidemiology / Q000401:mortality*; D013030:Spain / Q000453:epidemiology