title: Effect of body mass index on survival in patients having aortic valve replacement for aortic stenosis with or without concomitant coronary artery bypass grafting.
abstract: The purpose of this report is to describe the effect of body mass index (BMI) on 30-day and late outcome in patients having aortic valve replacement (AVR) for aortic stenosis (AS) with or without concomitant coronary artery bypass grafting. From January 2002 through June 2010 (8.5 years), 1,040 operatively excised stenotic aortic valves were submitted to the cardiovascular laboratory at Baylor University Medical Center at Dallas. Of the 1,040 cases 175 were eliminated because they had a previous cardiac operation. The present study included 865 adults whose AVR for AS was their first cardiac operation. Propensity-adjusted analysis showed that 30-day and late mortality were strongly and significantly associated with BMI. Decreased risk of 30-day and long-term mortality was observed for patients with BMI in the low 30s compared to patients with BMI in the mid 20s or >40 kg/m(2). In conclusion, the findings in this study indicate a strong and significant adjusted association between BMI and 30-day and long-term mortality in patients having AVR for AS with or without concomitant coronary artery bypass grafting. Better survival was observed in patients with BMIs in the low 30s compared to patients with BMIs in the mid 20s and >40 kg/m(2).
authors: Baylor Heart and Vascular Institute, Baylor University Medical Center, Dallas, Texas, USA. wc.roberts@baylorhealth.edu
authors: William Clifford
authors: WC
authors: Roberts
authors: Carey Camille
authors: CC
authors: Roberts
authors: Travis James
authors: TJ
authors: Vowels
authors: Jong Mi
authors: JM
authors: Ko
authors: Giovanni
authors: G
authors: Filardo
authors: Baron Lloyd
authors: BL
authors: Hamman
authors: Gregory John
authors: GJ
authors: Matter
authors: Albert Carl
authors: AC
authors: Henry
authors: Robert Frederick
authors: RF
authors: Hebeler
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001024:Aortic Valve Stenosis / Q000401:mortality* / Q000601:surgery*; D015992:Body Mass Index; D001026:Coronary Artery Bypass; D005260:Female; D019918:Heart Valve Prosthesis Implantation; D006801:Humans; D008297:Male; D008875:Middle Aged; D015996:Survival Rate; D055815:Young Adult