title: PI3K/AKT/mTORC1 and MEK/ERK signaling in T-cell acute lymphoblastic leukemia: new options for targeted therapy.
authors: Cellular Signalling Laboratory, Department of Anatomical Sciences, University of Bologna, Italy. alberto.martelli@unibo.it
authors: Alberto M
authors: AM
authors: Martelli
authors: Giovanna
authors: G
authors: Tabellini
authors: Francesca
authors: F
authors: Ricci
authors: Camilla
authors: C
authors: Evangelisti
authors: Francesca
authors: F
authors: Chiarini
authors: Roberta
authors: R
authors: Bortul
authors: James A
authors: JA
authors: McCubrey
authors: Francesco Antonio
authors: FA
authors: Manzoli
mesh_terms: D015153:Blotting, Western; D049109:Cell Proliferation / Q000187:drug effects; D002470:Cell Survival / Q000187:drug effects; D002478:Cells, Cultured; D006801:Humans; D015851:Interleukin-7 / Q000494:pharmacology; D016906:Interleukin-9 / Q000494:pharmacology; D000076222:Mechanistic Target of Rapamycin Complex 1; D020929:Mitogen-Activated Protein Kinase Kinases / Q000235:genetics / Q000378:metabolism*; D046912:Multiprotein Complexes / Q000235:genetics / Q000378:metabolism*; D019869:Phosphatidylinositol 3-Kinases / Q000235:genetics / Q000378:metabolism*; D054218:Precursor T-Cell Lymphoblastic Leukemia-Lymphoma / Q000378:metabolism*; D051057:Proto-Oncogene Proteins c-akt / Q000235:genetics / Q000378:metabolism*; D015398:Signal Transduction / Q000235:genetics / Q000502:physiology; D058570:TOR Serine-Threonine Kinases / Q000235:genetics / Q000378:metabolism*
chemical_list: D015851:Interleukin-7; D016906:Interleukin-9; D000076222:Mechanistic Target of Rapamycin Complex 1; D020929:Mitogen-Activated Protein Kinase Kinases; D046912:Multiprotein Complexes; D019869:Phosphatidylinositol 3-Kinases; D051057:Proto-Oncogene Proteins c-akt; D058570:TOR Serine-Threonine Kinases