title: Endovascular management of the arteria profunda femoralis: long-term angiographic and clinical outcomes.
abstract: OBJECTIVE
  This study was designed to investigate the long-term angiographic and clinical outcomes of percutaneous transluminal angioplasty (PTA) of the arteria profunda femoralis (PFA), in a series of patients suffering from critical limb ischemia (CLI) or severe intermittent claudication (IC).
  
  
  METHODS
  Our department's database was searched to identify patients who underwent PTA or bail-out stenting of the PFA. Among the study's inclusion criteria were Rutherford categories 3-6 and ≥70% stenosis of the PFA. Only de novo stenotic lesions were assessed. Primary endpoints were technical success, angiographic lesion primary patency, angiographic binary in-lesion restenosis, and target lesion recanalization (TLR) rates. Secondary endpoints included patient survival, limb salvage, and complication rates. Patient's baseline demographics, lesion, and procedural details were analyzed.
  
  
  RESULTS
  Between 2001 and 2011, 20 consecutive patients (17 males) with a mean age of 73 ± 9 (range 53-87) years underwent PTA or bail-out stenting in 23 PFA lesions. Critical limb ischemia was the indication in eight of 20 patients (40%). The mean lesion length was 31 ± 9.5 mm. The procedural technical success was 100% (23/23), whereas mean time angiographic and clinical follow-up was 26.8 ± 24.6 months. According to the Kaplan-Meier analysis, primary patency and binary restenosis rate were 95 and 86.1% respectively up to 8 years follow-up. No TLR procedures were performed. The 8-year patient survival and limb salvage rates were 87.5 and 84.7% respectively.
  
  
  CONCLUSIONS
  PTA or stenting of focal, stenotic, PFA lesions, in patients suffering from CLI or IC, exhibit high long-term primary patency rates, as well as low binary restenosis and TLR rates. Large, multicenter studies are required to validate these results.
authors: Department of Diagnostic and Interventional Radiology, Patras University Hospital, School of Medicine, Rion, Greece. karnaby@med.upatras.gr
authors: Dimitrios
authors: D
authors: Karnabatidis
authors: Stavros
authors: S
authors: Spiliopoulos
authors: Georgios
authors: G
authors: Pastromas
authors: Kostantinos
authors: K
authors: Katsanos
authors: Dimitrios
authors: D
authors: Siablis
mesh_terms: D000368:Aged; D000792:Angiography; D000800:Angioplasty, Balloon; D000925:Anticoagulants / Q000627:therapeutic use; D015897:Comorbidity; D005260:Female; D005263:Femoral Artery / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D006801:Humans; D007383:Intermittent Claudication / Q000000981:diagnostic imaging / Q000601:surgery*; D007511:Ischemia / Q000000981:diagnostic imaging / Q000601:surgery*; D007866:Leg / Q000098:blood supply*; D023821:Limb Salvage; D008297:Male; D018709:Statistics, Nonparametric; D015607:Stents; D015996:Survival Rate; D016896:Treatment Outcome; D014654:Vascular Patency
chemical_list: D000925:Anticoagulants