title: [Küttner's tumor (chronic sclerosing sialadenitis) - a rare cause of submandibular gland enlargement].
abstract: Küttner's tumor is a benign tumour-like lesion of the salivary glands. Predominantly affects the submandibular gland. It is also known as chronic sclerosing sialoadenitis or cirrhosis of submandibular gland. This is an underrecognized entity in the surgical pathology and cytology literature. Most patients experience recurrent pain, discharge and swelling that is often associated with eating, but others only have asymptomatic hard swelling of the submandibular gland. Histologic examination of the excised submandibular glands revealed preserved lobular architecture, thickening of interlobular septa by sclerotic tissue, dense lymphoplasmacytic infiltrate, preservation of ducts with periductal fibrosis, and variable loss of acini. The morphologic appearance, in conjunction with the elevated IgG4 expression, distinguishes chronic sclerosing sialadenitis from other inflammatory diseases of the salivary glands. Chronic sclerosing sialadenitis belongs to the spectrum of IgG4-related diseases. We present a case of Küttner's tumor in a 62-year-old female treated by surgery. Although this disease was first described by Küttner in 1896, this clinical entity which masquerades as carcinoma is underdiagnosed by many surgeons. There is not enough evidence to support any diagnostic means that could help in the differential diagnosis of this benign condition. Given the high rate of malignancy in firm, painless lesions of the submandibular gland, surgical excision is often advocated and Küttner's tumor is usually diagnosed by the histopathologist.
authors: Katedra i Klinika Laryngologii SUM w Katowicach. jmarkow1@poczta.onet.pl
authors: Jarosław
authors: J
authors: Markowski
authors: Tatiana
authors: T
authors: Gierek
authors: Małgorzata
authors: M
authors: Witkowska
authors: Jarosław
authors: J
authors: Paluch
authors: Monika
authors: M
authors: Swiderek
authors: Ewa
authors: E
authors: Zielińska-Pająk
authors: Jacek
authors: J
authors: Pająk
authors: Lucyna
authors: L
authors: Klimczak-Gołąb
authors: Katarzyna
authors: K
authors: Smółka
mesh_terms: D044963:Biopsy, Fine-Needle; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008875:Middle Aged; D018987:Salivary Ducts / Q000473:pathology* / Q000601:surgery; D012468:Salivary Gland Neoplasms / Q000473:pathology* / Q000601:surgery; D012793:Sialadenitis / Q000473:pathology* / Q000601:surgery; D013363:Submandibular Gland / Q000473:pathology* / Q000601:surgery