title: [Research progress of construction of tissue engineered osteochondral composites].
abstract: OBJECTIVE
  To review the recent progress of the researches in construction of tissue engineered osteochondral composites, and to discuss the challenges in construction of tissue engineered osteochondral composites.
  
  
  METHODS
  The recent literature on the construction of tissue engineered osteochondral composites was extensively reviewed and analyzed.
  
  
  RESULTS
  The studies on the construction of tissue engineered osteochondral composites are relatively more in vivo, the current focus is that different tissues derived mesenchymal stem cells are widely used to be seed cells; single-phase scaffold has been limited, studies on biphase scaffold and triphase scaffold are new trends; the design and performance of bioreactor need to be further optimized in the future.
  
  
  CONCLUSIONS
  The construction of tissue engineered osteochondral composites will be a promising method for the treatment of cartilage defects.
authors: Department of Orthopaedics and Traumatology, Nanfang Hospital, Southern Medical University, Guangzhou Guangdong 510515, PR China.
authors: Yongtao
authors: Y
authors: Zhang
authors: Dan
authors: D
authors: Jin
mesh_terms: D019149:Bioreactors; D001842:Bone and Bones; D002356:Cartilage; D002478:Cells, Cultured; D019902:Chondrocytes; D059630:Mesenchymal Stem Cells / Q000166:cytology; D015607:Stents; D023822:Tissue Engineering / Q000379:methods*