title: Fatal dengue hemorrhagic fever imported into Germany.
abstract: Dengue virus (DENV) is an arthropod-borne virus (family Flaviviridae) causing dengue fever or dengue hemorrhagic fever. Here, we report the first fatal DENV infection imported into Germany. A female traveler was hospitalized with fever and abdominal pain after returning from Ecuador. Due to a suspected acute acalculous cholecystitis, cholecystectomy was performed. After cholecystectomy, severe spontaneous bleeding from the abdominal wound occurred and the patient died. Postmortem analysis of transudate and tissue demonstrated a DENV secondary infection of the patient and a gallbladder wall thickening (GBWT) due to an extensive edema.
authors: Department of Virology, Clinical Virology Laboratory, Bernhard Nocht Institute for Tropical Medicine, Bernhard-Nocht-Strasse 74, 20359 Hamburg, Germany. jonassi@gmx.de
authors: J
authors: J
authors: Schmidt-Chanasit
authors: K
authors: K
authors: Tenner-Racz
authors: D
authors: D
authors: Poppert
authors: P
authors: P
authors: Emmerich
authors: C
authors: C
authors: Frank
authors: C
authors: C
authors: Dinges
authors: R
authors: R
authors: Penning
authors: A
authors: A
authors: Nerlich
authors: P
authors: P
authors: Racz
authors: S
authors: S
authors: Günther
mesh_terms: D000328:Adult; D017809:Fatal Outcome; D005260:Female; D005858:Germany; D006801:Humans; D019595:Severe Dengue / Q000401:mortality*; D014195:Travel