title: Selenium, thiobarbituric acid reactive substances, and thyroid hormone activation in broilers supplemented with selenium as selenized yeast or sodium selenite.
abstract: The objective of this experiment was to compare the efficiencies of sodium selenite (SS) and selenized yeast (SY) supplemented at different doses (0.05 and 0.30 mg Se/kg feed) with respect to plasma glutathione peroxidase (Gpx) activity, extent of oxidative lipid injury, and thyroid hormone activation in broilers during the first four weeks of growth. Results indicate a significant increase in plasma Gpx activity and reduction in thiobarbituric acid reactive substances (TBARS) in all supplemented groups at 4 weeks of age compared to 2-week-old chicks. Plasma thyronine activation was highest in SY supplemented broilers. It can be concluded that in the first 4 weeks of broiler life selenite has a more efficient antioxidative effect which is reflected in lower plasma and liver TBARS values. However, broiler feed supplementation with selenized yeast results in a more proficient conversion of T4 to T3.
authors: Faculty of Veterinary Medicine, University of Belgrade, Department of Physiology and Biochemistry, Bulevar Oslobodjenja 18, 11000 Belgrade, Serbia. olja@vet.bg.ac.rs
authors: Olivera
authors: O
authors: Valcić
authors: Ivan B
authors: IB
authors: Jovanović
authors: Svetlana
authors: S
authors: Milanović
mesh_terms: D000821:Animal Feed / Q000032:analysis; D000824:Animal Nutritional Physiological Phenomena; D000818:Animals; D002645:Chickens / Q000378:metabolism*; D004032:Diet / Q000662:veterinary; D019587:Dietary Supplements; D004305:Dose-Response Relationship, Drug; D005979:Glutathione Peroxidase / Q000097:blood / Q000378:metabolism; D015227:Lipid Peroxidation; D008099:Liver / Q000378:metabolism; D012643:Selenium / Q000008:administration & dosage / Q000378:metabolism* / Q000494:pharmacology*; D018038:Sodium Selenite / Q000008:administration & dosage / Q000494:pharmacology*; D017392:Thiobarbituric Acid Reactive Substances / Q000378:metabolism*; D013963:Thyroid Hormones / Q000378:metabolism*; D015003:Yeasts
chemical_list: D017392:Thiobarbituric Acid Reactive Substances; D013963:Thyroid Hormones; D005979:Glutathione Peroxidase; D012643:Selenium; D018038:Sodium Selenite