title: Two cases of spontaneous regression of congenital cholesteatomas.
abstract: Congenital cholesteatoma arises behind a normal, intact tympanic membrane and is most plausibly explained by the persistence of fetal epidermoid formation. It is generally accepted that cholesteatoma in children has greater aggressive growth activity than that in adults. The congenital type of cholesteatoma starts as a small pearl in the middle ear and eventually grows to involve the ossicles and then the attic and mastoid, causing varying degrees of destruction and functional impairment. However, here we report the cases of two children with congenital cholesteatoma which disappeared spontaneously during the follow-up period. To the best of our knowledge, this is the first report on the spontaneous regression of congenital cholesteatoma. On the basis of the two cases, we could take a "wait and watch" attitude for congenital cholesteatoma in the absence of severe infection, hearing loss, or bone destruction in the middle ear.
authors: Jichi Medical University, Saitama Medical Center, 1-847 Amanuma, Saitama 330-8503, Japan. kozuekk@jichi.ac.jp
authors: Kozue
authors: K
authors: Kodama
authors: Mariko
authors: M
authors: Hara
authors: Masayo
authors: M
authors: Hasegawa
authors: Shingo
authors: S
authors: Matsuzawa
authors: Masahiro
authors: M
authors: Shinnabe
authors: Hiromi
authors: H
authors: Kanazawa
authors: Naohiro
authors: N
authors: Yoshida
authors: Yukiko
authors: Y
authors: Iino
mesh_terms: D002675:Child, Preschool; D018424:Cholesteatoma, Middle Ear / Q000151:congenital* / Q000175:diagnosis* / Q000503:physiopathology; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D038781:Otoscopy / Q000379:methods; D012075:Remission, Spontaneous; D014057:Tomography, X-Ray Computed / Q000379:methods