title: Maternal and neonatal outcomes following induction of labor: a cohort study.
abstract: OBJECTIVE
  To evaluate maternal and neonatal outcomes associated with birth at term by week of gestational age and also by onset of labor.
  
  
  METHODS
  Cohort study.
  
  
  METHODS
  A state-wide perinatal outcome database.
  
  
  METHODS
  28,626 women with spontaneous onset of labor, induction of labor for recognized indications and induction of labor for non-recognized indications.
  
  
  METHODS
  Cohort study utilizing a validated dataset comparing outcomes with type of onset of labor using a log binomial model.
  
  
  METHODS
  Cesarean section, assisted vaginal birth, important measures of maternal and neonatal morbidity.
  
  
  RESULTS
  Induction of labor for non-recognized indications was associated with a significantly increased risk of a range of outcomes, including cesarean section (RR 1.67, 95% CI 1.55-1.80). The lowest risk of adverse maternal and infant outcome occurred with birth between 38 and 39 weeks and with the spontaneous onset of labor.
  
  
  CONCLUSIONS
  Induction of labor for non-recognized indications at term is associated with an increased risk of adverse outcomes. Caution is warranted with a liberal policy of induction of labor at term in an otherwise uncomplicated pregnancy.
authors: Discipline of Obstetrics and Gynaecology, University of Adelaide, South Australia, Australia. rosalie.grivell@adelaide.edu.au
authors: Rosalie M
authors: RM
authors: Grivell
authors: Aimee J
authors: AJ
authors: Reilly
authors: Helena
authors: H
authors: Oakey
authors: Annabelle
authors: A
authors: Chan
authors: Jodie M
authors: JM
authors: Dodd
mesh_terms: D000328:Adult; D001720:Birth Injuries / Q000453:epidemiology / Q000209:etiology*; D001724:Birth Weight; D002585:Cesarean Section / Q000706:statistics & numerical data; D005113:Extraction, Obstetrical / Q000706:statistics & numerical data; D005260:Female; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D015931:Intensive Care, Neonatal / Q000706:statistics & numerical data; D007751:Labor, Induced / Q000009:adverse effects*; D015233:Models, Statistical; D007744:Obstetric Labor Complications / Q000453:epidemiology / Q000209:etiology*; D054238:Perinatal Mortality; D011247:Pregnancy; D011256:Pregnancy Outcome; D011446:Prospective Studies; D012306:Risk