title: [Epidemiological study of thalasaemia among children in Xishuangbanna, Dehong and Nujiang of Yunnan province].
abstract: OBJECTIVE
  To investigate the carrier rate of thalasaemia among the children of 10 minority ethnic groups in 3 border states (Xishuangbanna, Dehong and Nujiang) of Yunnan Province.
  
  
  METHODS
  A total of 6562 samples of children under 10 years old were analyzed by blood cell automatic analysis and hemoglobin electrophoresis.
  
  
  RESULTS
  The overall carrier frequency of thalasaemia was highest (46.2%) in Dehong, and lowest (30.6%) in Nujiang. The carrier frequency of beta-thalasaemia was the highest (40.6%) in Achang, and lowest (2.5%) in Dulong. The carrier frequency of alpha-thalasaemia was the highest (22.1%) in Dai from Xishuangbanna, followed by Dulong (19.1%).
  
  
  CONCLUSIONS
  Thalasaemia carrier rates were high among the children of 10 minority ethnic groups in Yunnan. There were regional differences in their incidences. The results provide a valuable basis for thalasaemia prevention in Yunnan minorities in the three border states.
authors: Yunnan Provincial Women and Children's Hospital, Kunming, Yunnan, People's Republic of China.
authors: Li-qin
authors: LQ
authors: Yao
authors: Tuan-biao
authors: TB
authors: Zou
authors: Fa-bin
authors: FB
authors: Yang
authors: Li-sha
authors: LS
authors: Hu
authors: Qian
authors: Q
authors: Chen
authors: Li-mei
authors: LM
authors: Fan
authors: Zhong-ming
authors: ZM
authors: Zhao
authors: Jin-tao
authors: JT
authors: Liu
authors: Xing-tian
authors: XT
authors: Wang
mesh_terms: D002648:Child; D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D006455:Hemoglobins, Abnormal / Q000235:genetics; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008913:Minority Groups; D015995:Prevalence; D013789:Thalassemia / Q000208:ethnology* / Q000235:genetics; D017085:alpha-Thalassemia / Q000453:epidemiology / Q000235:genetics; D017086:beta-Thalassemia / Q000453:epidemiology / Q000235:genetics
chemical_list: D006455:Hemoglobins, Abnormal