title: The effect of adenotonsillectomy on right ventricle function and pulmonary artery pressure in children with adenotonsillar hypertrophy.
abstract: OBJECTIVE
  Adenotonsillar hypertrophy (ATH) is the most common cause of upper airway obstruction in children. Severe upper airway obstruction may have an effect on chronic alveolar hypoventilation, which consequently may lead to right ventricle (RV) dysfunction induced by hypoxemic pulmonary vasoconstriction. The investigators aimed to study RV function and mean pulmonary artery pressure (mPAP) in patients with ATH who were undergoing adenotonsillectomy by using tissue Doppler echocardiography (TDE).
  
  
  METHODS
  The study examined 27 children with ATH who had a mean age of 8 ± 2 years. The subjects were comprised 17 (63%) males and 10 (37%) females. Hypertrophy of the tonsils was graded according to the Brodsky scale. Children having either grade 3 or 4 hypertrophied adenotonsils were recruited for the study. Adenotonsillectomy was performed on all subjects in the study group and echocardiographic examination was repeated 3 months postoperatively.
  
  
  RESULTS
  Tricuspid Em significantly increased after adenotonsillectomy (17.7 ± 3.6 vs. 19.1 ± 5.5, p=0.04). The RV myocardial performance index (MPI) and mPAP significantly decreased after adenotonsillectomy (RV MPI: 0.57 ± 0.13 vs. 0.40 ± 0.12, p<0.001 and mPAP (mmHg): 31 ± 9 vs. 25 ± 7, p=0.001).
  
  
  CONCLUSIONS
  The results of this study, evaluated with the results of previous studies, demonstrated that adenotonsillectomy improved RV performance and reduced mPAP in children with ATH.
authors: Gaziosmanpasa University, Medical Faculty, Otolaryngology Department, Tokat, Turkey.
authors: Sema
authors: S
authors: Koc
authors: Metin
authors: M
authors: Aytekin
authors: Nihat
authors: N
authors: Kalay
authors: Mustafa
authors: M
authors: Ozcetin
authors: Turgay
authors: T
authors: Burucu
authors: Kerem
authors: K
authors: Ozbek
authors: Atac
authors: A
authors: Celik
authors: Hasan
authors: H
authors: Kadi
authors: Sefa
authors: S
authors: Gulturk
authors: Fatih
authors: F
authors: Koc
mesh_terms: D000233:Adenoidectomy; D000234:Adenoids / Q000473:pathology* / Q000601:surgery*; D000402:Airway Obstruction / Q000209:etiology; D001794:Blood Pressure / Q000502:physiology; D002648:Child; D015331:Cohort Studies; D015150:Echocardiography, Doppler; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006976:Hypertension, Pulmonary / Q000175:diagnosis / Q000209:etiology / Q000517:prevention & control*; D006984:Hypertrophy / Q000150:complications / Q000601:surgery; D008297:Male; D014066:Palatine Tonsil / Q000473:pathology* / Q000601:surgery*; D011651:Pulmonary Artery / Q000502:physiology; D020127:Recovery of Function; D014068:Tonsillectomy; D016896:Treatment Outcome; D018497:Ventricular Dysfunction, Right / Q000000981:diagnostic imaging / Q000209:etiology / Q000517:prevention & control*; D016278:Ventricular Function, Right / Q000502:physiology*