title: Task-induced deactivation and the "resting" state.
abstract: Task-induced decreases in blood flow and the widespread use of "resting" baselines produced unexpected and discrepant results in early cognitive imaging studies, especially in language comprehension experiments. Here I describe from a personal perspective some of the events and thought processes leading to the first hypothesis-driven fMRI study of the "resting" state.
authors: Department of Neurology, Medical College of Wisconsin, Milwaukee, WI 53226, USA. jbinder@mcw.edu
authors: Jeffrey R
authors: JR
authors: Binder
mesh_terms: D001921:Brain / Q000098:blood supply / Q000502:physiology*; D001931:Brain Mapping / Q000266:history* / Q000379:methods; D002560:Cerebrovascular Circulation / Q000502:physiology; D003071:Cognition / Q000502:physiology; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000266:history* / Q000379:methods; D012146:Rest / Q000502:physiology*