title: Cortical evoked potentials in children of diabetic mothers.
abstract: Type 1 diabetic mothers' infants show a delay of visual evoked potential (VEP) significantly related to some parameters of poor metabolic control during pregnancy. In the present paper we analyzed the characteristics of VEPs and somatosensory evoked potentials (SEPs) recorded in 16 three-year-old type 1 diabetic mothers' children (DMC). Compared with controls (23 nondiabetic mothers' healthy matched children), DMC showed significantly delayed mean latency of VEP (P2) and SEP (P22). In 3 cases (19%), we found pathological responses (+3 SD from the mean value of controls) of VEPs and SEPs. At the age of 3 years, the offspring of type 1 diabetic mothers showed delay of cortical evoked responses in both visual and somatosensory systems.
authors: Department of Pediatrics and Child Neuropsychiatry, Faculty of Medicine and Dentistry, Sapienza University of Rome, 00185 Rome, Italy. mario.brinciotti@uniroma1.it
authors: Mario
authors: M
authors: Brinciotti
authors: Angela
authors: A
authors: Napoli
authors: Antonio
authors: A
authors: Mittica
authors: Olimpia
authors: O
authors: Bitterman
authors: Maria
authors: M
authors: Matricardi
mesh_terms: D000367:Age Factors; D000704:Analysis of Variance; D016022:Case-Control Studies; D016009:Chi-Square Distribution; D002675:Child, Preschool; D048909:Diabetes Complications / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology; D003922:Diabetes Mellitus, Type 1 / Q000150:complications* / Q000503:physiopathology; D004558:Electric Stimulation; D004569:Electroencephalography; D005073:Evoked Potentials, Somatosensory; D005074:Evoked Potentials, Visual; D005260:Female; D006801:Humans; D007223:Infant; D007558:Italy; D008297:Male; D008475:Median Nerve; D010775:Photic Stimulation; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D011930:Reaction Time; D013997:Time Factors; D014793:Visual Cortex / Q000503:physiopathology*