title: A strong case for viral genetic factors in HIV virulence.
abstract: HIV infections show great variation in the rate of progression to disease, and the role of viral genetic factors in this variation had remained poorly characterized until recently. Now a series of four studies [1-4] published within a year has filled this important gap and has demonstrated a robust effect of the viral genotype on HIV virulence.
authors: Institute of Biology, Eötvös Loránd University, Pázmány P. s. 1/C, 1117 Budapest, Hungary.
authors: Viktor
authors: V
authors: Müller
authors: Department of Infectious Disease Epidemiology, School of Public Health, Imperial College London, London W2 1PG, UK.
authors: Christophe
authors: C
authors: Fraser
authors: Department of Microbiology, University of Washington School of Medicine, Seattle, WA 98195, USA.
authors: Joshua T
authors: JT
authors: Herbeck
mesh_terms: D015658:HIV Infections / Q000821:virology*; D015497:HIV-1 / Q000235:genetics* / Q000472:pathogenicity* / Q000502:physiology; D006801:Humans; D019562:Viral Load; D014774:Virulence