title: The use of lymecycline and benzoyl peroxide for the treatment of progressive macular hypomelanosis: a prospective study.
abstract: Progressive macular hypomelanosis is a dermatosis of uncertain etiology. The participation of Propionibacterium acnes has been suggested in view of the response achieved following therapy with drugs that are active against this bacterium. This report describes a series of thirteen patients with progressive macular hypomelanosis who were treated with an association of lymecycline and benzoyl peroxide over a three-month period. Response to treatment was excellent and the positive results were maintained during the entire follow up period.
authors: Department of Dermatology, Universidade de Pernambuco, Recife, Brasil. silvana_cavalcanti@yahoo.com.br
authors: Silvana Maria de Morais
authors: SM
authors: Cavalcanti
authors: Marina Coutinho Domingues
authors: MC
authors: Querino
authors: Vera
authors: V
authors: Magalhães
authors: Emmanuel Rodrigues de
authors: ER
authors: França
authors: Marcelo
authors: M
authors: Magalhães
authors: Eliane
authors: E
authors: Alencar
mesh_terms: D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D001585:Benzoyl Peroxide / Q000008:administration & dosage*; D003879:Dermatologic Agents / Q000008:administration & dosage*; D004359:Drug Therapy, Combination; D005500:Follow-Up Studies; D006801:Humans; D017496:Hypopigmentation / Q000188:drug therapy*; D008194:Lymecycline / Q000008:administration & dosage*; D011446:Prospective Studies; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D003879:Dermatologic Agents; D008194:Lymecycline; D001585:Benzoyl Peroxide