title: Redox profile in liver of Leporinus macrocephalus exposed to different dissolved oxygen levels.
abstract: Aquatic organisms are continuously exposed to environmental variations, which can lead to physiological and biochemical alterations. Leporinus macrocephalus, known as piavuçu, is a migratory species that may be exposed to variations in dissolved oxygen levels. Studies evaluating oxidative changes undergone by this species in these conditions are scarce. Therefore, this investigation aimed at evaluating oxidative alterations in L. macrocephalus exposed to different oxygen levels for 96 h: 6.12 ± 0.18, 3.99 ± 0.17, 3.22 ± 0.17, 2.47 ± 0.30 and 0.710 ± 0.07 mg L(-1). At the end of the experimental period, fish were euthanized and livers used to determine lipid hydroperoxides, thiobarbituric acid reactive substances, catalase, glutathione-S-transferase, superoxide dismutase and thiol groups, which are an indirect measure of reduced glutathione. Results indicated a decrease in the studied parameters in hypoxic situations, suggesting a possible metabolic depression.
authors: Departamento de Fisiologia e Farmacologia, Universidade Federal de Santa Maria, Santa Maria, Brazil.
authors: A P K
authors: AP
authors: Riffel
authors: L O
authors: LO
authors: Garcia
authors: I A
authors: IA
authors: Finamor
authors: E M H
authors: EM
authors: Saccol
authors: M
authors: M
authors: Meira
authors: C
authors: C
authors: Kolberg
authors: A
authors: A
authors: Horst
authors: W
authors: W
authors: Partata
authors: S
authors: S
authors: Llesuy
authors: B
authors: B
authors: Baldisserotto
authors: M A
authors: MA
authors: Pavanato
mesh_terms: D025041:Animal Migration; D000818:Animals; D000975:Antioxidants / Q000378:metabolism; D002374:Catalase / Q000378:metabolism; D060125:Characiformes / Q000378:metabolism* / Q000502:physiology; D005393:Fish Diseases / Q000378:metabolism; D029941:Fish Proteins / Q000378:metabolism; D005978:Glutathione / Q000378:metabolism; D005982:Glutathione Transferase / Q000378:metabolism; D000860:Hypoxia / Q000378:metabolism / Q000662:veterinary; D015227:Lipid Peroxidation; D008099:Liver / Q000378:metabolism; D010084:Oxidation-Reduction; D018384:Oxidative Stress; D010100:Oxygen / Q000008:administration & dosage / Q000378:metabolism*; D045483:Rivers / Q000737:chemistry; D013482:Superoxide Dismutase / Q000378:metabolism; D017392:Thiobarbituric Acid Reactive Substances / Q000378:metabolism
chemical_list: D000975:Antioxidants; D029941:Fish Proteins; D017392:Thiobarbituric Acid Reactive Substances; D002374:Catalase; D013482:Superoxide Dismutase; D005982:Glutathione Transferase; D005978:Glutathione; D010100:Oxygen