title: Cardiometabolic biomarkers in young black girls: relations to body fatness and aerobic fitness, and effects of a randomized physical activity trial.
abstract: There is little evidence from randomized trials showing that physical activity alone influences biomarker profiles in youths. This study tested two hypotheses: (i) that elevated body fatness and poor fitness would be associated with unfavorable levels of cardiometabolic biomarkers in 8-12-y-old black girls (n = 242) and (ii) that a 10-mo PA intervention would have favorable effects on the fatness-related cardiometabolic biomarkers. At baseline, all fatness indices (i.e., percent body fat, visceral adipose tissue, BMI, and waist circumference) were significantly (P < 0.05) associated with unfavorable levels of insulin, glucose, systolic BP, diastolic BP, triglycerides, C-reactive protein (CRP), and fibrinogen. Aerobic fitness was significantly (P < 0.05) associated with favorable levels of insulin, CRP, fibrinogen, and HDL(2). The PA intervention had significant and favorable effects on fitness, fatness, and two biomarkers-resting heart rate and LDL cholesterol. More research is needed to clarify what types of interventions can enhance the cardiometabolic health of youths.
authors: Georgia Prevention Institute, Department of Pediatrics, Georgia Health Sciences University (Formerly the Medical College of Georgia), Augusta, GA 30912, USA.
authors: Bernard
authors: B
authors: Gutin
authors: Ryan A
authors: RA
authors: Harris
authors: Cheryl A
authors: CA
authors: Howe
authors: Maribeth H
authors: MH
authors: Johnson
authors: Haidong
authors: H
authors: Zhu
authors: Yanbin
authors: Y
authors: Dong