title: Depsitinuside: a new depside galactoside from an endophytic fungus isolated from Viburnum tinus.
abstract: Chromatographic purification of the extract of an endophytic fungal culture yielded depsitinuside (1), a new phenolic ester together with ergosterol (2) and (22E,24S)-24-methyl-5-α-cholesta-7,22-diene-3β,5,6β-triol (3). The structure of 1 was elucidated based on 1D, 2D NMR spectroscopy and high-resolution mass spectrometry, whereas the known compounds (2 and 3) were identified by (1)H NMR, mass spectrometry, and in comparison with the literature values. Compound 1 was evaluated for its enzyme inhibitory potential against acetylcholinesterase, butyrylcholinesterase and lipoxygenase, and was found inactive (10%-40% inhibition at a concentration of 2 mg/ml).
authors: Department of Chemistry , Baghdad-ul-Jadeed Campus, The Islamia University of Bahawalpur, Bahawalpur, 63100, Pakistan.
authors: Mamona
authors: M
authors: Nazir
authors: Misbah
authors: M
authors: Sultan
authors: Naheed
authors: N
authors: Riaz
authors: Maria
authors: M
authors: Hafeez
authors: Hidayat
authors: H
authors: Hussain
authors: Ishtiaq
authors: I
authors: Ahmed
authors: Barbara
authors: B
authors: Schulz
authors: Siegfried
authors: S
authors: Draeger
authors: Abdul
authors: A
authors: Jabbar
authors: Karsten
authors: K
authors: Krohn
authors: Muhammad
authors: M
authors: Ashraf
authors: Muhammad
authors: M
authors: Saleem
mesh_terms: D001203:Ascomycota / Q000737:chemistry*; D053630:Depsides / Q000737:chemistry / Q000302:isolation & purification*; D005697:Galactosides / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010154:Pakistan; D027925:Viburnum / Q000382:microbiology
chemical_list: D053630:Depsides; D005697:Galactosides; C569325:depsitinuside