title: A large Venous-Arterial PCO(2) Is Associated with Poor Outcomes in Surgical Patients.
abstract: Background. This study evaluated whether large venous-arterial CO(2) gap (PCO(2) gap) preoperatively is associated to poor outcome. Method. Prospective study which included adult high-risk surgical patients. The patients were pooled into two groups: wide [P(v-a)CO(2)] versus narrow [P(v-a)CO(2)]. In order to determine the best value to discriminate hospital mortality, it was applied a ROC (receiver operating characteristic) curve for the [P(v-a)CO(2)] values collected preoperatively, and the most accurate value was chosen as cut-off to define the groups. Results. The study included 66 patients. The [P(v-a)CO(2)] value preoperatively that best discriminated hospital mortality was 5.0 mmHg, area = 0.73. Preoperative patients with [P(v-a)CO(2)] more than 5.0 mmHg presented a higher hospital mortality (36.4% versus 4.5% P = 0.004), higher prevalence of circulatory shock (56.8% versus 22.7% P = 0.01) and acute renal failure postoperatively (27.3% versus 4.5% P = 0.02), and longer hospital length of stays 20.0 (14.0-30.0) versus 13.5 (9.0-25.0) days P = 0.01. Conclusions. The PCO(2) gap values more than 5.0 mmHg preoperatively were associated with worse postoperatively outcome.
authors: Anestesiologia e Cuidados Intensivos, Hospital do Servidor Público Estadual, 04039-901 São Paulo, SP, Brazil.
authors: João M
authors: JM
authors: Silva
authors: Amanda M Ribas R
authors: AM
authors: Oliveira
authors: Juliano Lopes
authors: JL
authors: Segura
authors: Marcel Henrique
authors: MH
authors: Ribeiro
authors: Carolina Nacevicius
authors: CN
authors: Sposito
authors: Diogo O
authors: DO
authors: Toledo
authors: Ederlon
authors: E
authors: Rezende
authors: Luiz M Sá
authors: LM
authors: Malbouisson