title: A case whose outcome is consistent with the possibility that if slow embryo cleavage is related to a male factor the prognosis is far greater than if it was related to an egg factor.
abstract: OBJECTIVE
  To determine if the male partner's sperm can be the cause of embryos with slow cleavage.
  
  
  METHODS
  Retrospective evaluation of shared donor oocyte pairs where two women shared one pool of oocytes from an oocyte donor.
  
  
  RESULTS
  Only one woman formed embryos that were all < 6 blastomeres in 376 paired cycles (total 752). With one previous IVF cycle where she formed only two embryos (5-cell and 4-cell) this woman had in five embryos formed all < 6-cells and four of five only 4-cells on day 3. In contrast, the woman who was donating half of the oocytes but had her half fertilized by her own male partner's sperm had only one of three with < 6-cells.
  
  
  CONCLUSIONS
  This study suggests that rarely the sperm may be the reason for slow cleaving embryos.
authors: The University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School at Camden Cooper Hospital/University Medical Center, Department of Obstetrics and Gynecology Division of Reproductive Endocrinology & Infertility, Camden, NJ, USA. laurie@ccivf.com
authors: J H
authors: JH
authors: Check
authors: B
authors: B
authors: Katsoff
authors: C
authors: C
authors: Wilson
authors: A
authors: A
authors: Bollendorf
mesh_terms: D000328:Adult; D001757:Blastomeres; D002970:Cleavage Stage, Ovum; D010064:Embryo Implantation; D004624:Embryo Transfer; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D008297:Male; D018587:Oocyte Donation; D009865:Oocytes / Q000166:cytology*; D011379:Prognosis; D013084:Sperm-Ovum Interactions