title: Mediastinal endodermal sinus tumor associated with fatal hemophagocytic syndrome.
abstract: The association of endodermal sinus tumor, known also as yolk sac tumor, of the mediastinum with hemophagocytic syndrome is exceedingly rare with only a few cases on record. We report a 24-year-old male who had a large mediastinal germ cell tumor, proven to be an endodermal sinus tumor on biopsy. The patient developed pancytopenia and coagulopathy related to associated hemophagocytic syndrome, with a fatal outcome. A brief review of the relevant literature is presented as well.
authors: Department of Surgery, King Fahad Specialist Hospital, Dammam, Saudi Arabia.
authors: Ikram Ul Haq
authors: IU
authors: Chaudary
authors: Shoukat Ahmad
authors: SA
authors: Bojal
authors: Adel
authors: A
authors: Attia
authors: Battal
authors: B
authors: Al-Dossary
authors: A fra Qasem
authors: Af
authors: Al Dayel
authors: Samir Sami
authors: SS
authors: Amr
mesh_terms: D001853:Bone Marrow / Q000473:pathology; D018240:Endodermal Sinus Tumor / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology; D017809:Fatal Outcome; D006801:Humans; D051359:Lymphohistiocytosis, Hemophagocytic / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology; D008297:Male; D008479:Mediastinal Neoplasms / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology; D014057:Tomography, X-Ray Computed; D055815:Young Adult