title: Mitral valve repair in a patient with acromegaly.
abstract: We report on a successful mitral valve (MV) repair and modified Cox maze procedure in a 35-year-old male patient with acromegaly, associated with severe mitral regurgitation and atrial fibrillation. He underwent a transsphenoidal adenomectomy, 7 months after the cardiac operation, and IGF-I level was normalized postoperatively. Valvular disease in patients with acromegaly is associated with hormonal activity, and control of growth hormone and insulin-like growth factor I excesses is important in the long-term durability of mitral valve repair.
authors: Division of Thoracic and Cardiovascular Surgery, Department of Surgery, Showa University, Tokyo, Japan. tomoto@med.showa-u.ac.jp
authors: Tadashi
authors: T
authors: Omoto
authors: Takeo
authors: T
authors: Tedoriya
authors: Masaya
authors: M
authors: Oi
authors: Naoko
authors: N
authors: Nagano
authors: Tadamasa
authors: T
authors: Miyauchi
authors: Noboru
authors: N
authors: Ishikawa
mesh_terms: D000172:Acromegaly / Q000097:blood / Q000209:etiology* / Q000601:surgery; D000236:Adenoma / Q000097:blood / Q000150:complications* / Q000601:surgery; D000328:Adult; D001281:Atrial Fibrillation / Q000175:diagnosis / Q000209:etiology / Q000601:surgery; D015415:Biomarkers / Q000097:blood; D006348:Cardiac Surgical Procedures; D017115:Catheter Ablation; D018618:Echocardiography, Doppler, Color; D049912:Growth Hormone-Secreting Pituitary Adenoma / Q000097:blood / Q000150:complications* / Q000601:surgery; D019382:Human Growth Hormone / Q000097:blood; D006801:Humans; D007334:Insulin-Like Growth Factor I / Q000378:metabolism; D008297:Male; D008944:Mitral Valve Insufficiency / Q000097:blood / Q000175:diagnosis / Q000209:etiology / Q000601:surgery*; D012720:Severity of Illness Index; D016896:Treatment Outcome
chemical_list: D015415:Biomarkers; D019382:Human Growth Hormone; D007334:Insulin-Like Growth Factor I