title: Active cobalt catalyst for the cleavage of benzyl ether.
abstract: An improved method for the deprotection of benzyl ethers using a catalytic amount of Co(2)(CO)(8) in the presence of Me(2)PhSiH and CO (1 atm) is described. The deprotection reaction is compatible with double bond or sulfur-containing substrates. The method also tolerates other functional groups, such as Ac, Piv, and Bz, and shows potential selectivity in perbenzylated monosaccharides.
authors: The State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, P. R. China.
authors: Bo
authors: B
authors: Wang
authors: Zhaojun
authors: Z
authors: Yin
authors: Yangbing
authors: Y
authors: Li
authors: Ting-Xiang
authors: TX
authors: Yang
authors: Xiang-Bao
authors: XB
authors: Meng
authors: Zhong-Jun
authors: ZJ
authors: Li
mesh_terms: D002384:Catalysis; D003035:Cobalt / Q000737:chemistry*; D015394:Molecular Structure; D010647:Phenyl Ethers / Q000737:chemistry*
chemical_list: D010647:Phenyl Ethers; D003035:Cobalt