title: Determinants for postoperative complications after laparoscopic intestinal resection for Crohn's disease.
abstract: BACKGROUND
  There is lack of studies that define parameters predictive of complications following laparoscopic resection for Crohn's disease.
  
  
  METHODS
  Between 1998 and 2008, 182 patients underwent laparoscopic intestinal resection for Crohn's disease at a single institution. Conversion occurred in 12 patients (6.6%). We aimed to identify risk factors for short-term postoperative complications (<30 days) by using univariate and multiple regression tests. Complications were defined according to the Clavien-Dindo classification (grades I-V). Data were obtained from an institutional database and individual chart review retrospectively.
  
  
  RESULTS
  There were 25 (13.7%) complications after surgery. According to the Clavien-Dindo classification, complications were classified as grade I in 9 patients, grade II in 9 patients, and grade IIIb in 7 patients. There were no deaths after laparoscopic surgery. A low level of hemoglobin after surgery (r (s )= -0.15, P = 0.0441) and an elevated CRP before surgery (r (s )= -0.16, P = 0.0346) seemed to increase the likelihood of postoperative complications.
  
  
  CONCLUSIONS
  Laparoscopic surgery can be performed safely in Crohn's disease patients. An increased inflammation process before operation seems to be associated an eventful postoperative course.
authors: Department of General Surgery, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria. stefan.riss@meduniwien.ac.at
authors: Stefan
authors: S
authors: Riss
authors: Clemens
authors: C
authors: Bittermann
authors: Katrin
authors: K
authors: Schwameis
authors: Ivan
authors: I
authors: Kristo
authors: Martina
authors: M
authors: Mittlböck
authors: Friedrich
authors: F
authors: Herbst
authors: Anton
authors: A
authors: Stift
mesh_terms: D000328:Adult; D015992:Body Mass Index; D003424:Crohn Disease / Q000601:surgery*; D005260:Female; D006801:Humans; D010535:Laparoscopy / Q000009:adverse effects*; D007902:Length of Stay; D008297:Male; D011183:Postoperative Complications / Q000209:etiology; D012307:Risk Factors; D055815:Young Adult