title: [HIF-1 signal pathway in cellular response to hypoxia].
abstract: HIF-1 is composed of HIF-1α and HIF-1β subunits. It promotes target genes transcription under hypoxia and plays essential roles in cell development, physiological adaptations, and pathological processes. In the past 10 years, the research on signaling pathways of HIF-1 in response to cell hypoxia stress, especially on HIF-1α-mediated gene transcription has made great progress.
authors: Department of Basic Medical Sciences, Zhejiang University School of Medicine, Hangzhou, China.
authors: Ping-ping
authors: PP
authors: Wang
authors: Fan-ping
authors: FP
authors: Kong
authors: Xue-qun
authors: XQ
authors: Chen
authors: Ji-zeng
authors: JZ
authors: Du
mesh_terms: D000818:Animals; D015687:Cell Hypoxia / Q000502:physiology; D006801:Humans; D051793:Hypoxia-Inducible Factor 1 / Q000378:metabolism*; D015398:Signal Transduction
chemical_list: D051793:Hypoxia-Inducible Factor 1