title: Intraoperative resistance index measured with transsonic flowmeter on kidney graft artery can predict early and long-term graft function.
abstract: BACKGROUND
  Resistive index (RI) measured by Doppler sonography in the early period after kidney transplantation is a well-known predictor of kidney transplant outcome. The purpose of this study was to analyze the impact of RI values calculated intraoperatively in renal allograft artery using transit time flowmetry (TTF) on both early and long-term kidney graft function.
  
  
  METHODS
  TTF was performed on 72 patients who received kidney grafts fed by a single artery. TTF was performed before wound closure. We excluded patients with an early acute rejection (n=8), an early graft loss (n=2), or primary graft nonfunction (n=1). Recipients were divided into RI tertile groups. The initial kidney graft function was defined as immediate (IGF), slow or delayed. Kidney graft estimated glomerular filtration rate (eGFR) was analyzed upon long-term follow-up.
  
  
  RESULTS
  Patients with a low RI (<0.57) showed the highest incidence of immediate graft function (65% versus 5.3%), whereas the high RI group (>0.70). Show the most frequent rate of delayed graft function (52.6% versus 15%). Recipients with low RI values displayed significantly better eGFR (by at least 12 mL/min/1.73 m2) than those with medium or high RI values at all analyzed times; subjects with medium or high RI showed similar eGFR at 48-months.
  
  
  CONCLUSIONS
  An high RI value measured intraoperatively was a valuable predictor of inferior early and long-term kidney graft function.
authors: Department of General, Vascular and Transplant Surgery, Medical University of Silesia, Katowice, Poland. robertk@hot.pl
authors: R
authors: R
authors: Król
authors: J
authors: J
authors: Chudek
authors: A
authors: A
authors: Kolonko
authors: J
authors: J
authors: Ziaja
authors: J
authors: J
authors: Pawlicki
authors: A
authors: A
authors: Wiecek
authors: L
authors: L
authors: Cierpka
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D045268:Flowmeters; D005919:Glomerular Filtration Rate; D006801:Humans; D016030:Kidney Transplantation / Q000000981:diagnostic imaging* / Q000502:physiology; D008297:Male; D008875:Middle Aged; D016343:Monitoring, Intraoperative; D012077:Renal Artery / Q000000981:diagnostic imaging* / Q000502:physiology; D012079:Renal Circulation; D013997:Time Factors; D016896:Treatment Outcome; D018608:Ultrasonography, Doppler; D014655:Vascular Resistance; D055815:Young Adult