title: Ru-catalyzed asymmetric hydrogenation of γ-heteroatom substituted β-keto esters.
abstract: A series of enantiomerically pure γ-heteroatom substituted β-hydroxy esters were synthesized with high enantioselectivities (up to 99.1% ee) by hydrogenation of γ-heteroatom substituted β-keto esters in the presence of Ru-(S)-SunPhos catalyst. These asymmetric hydrogenations provide key building blocks for a variety of naturally occurring and biologically active compounds.
authors: School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University, Shanghai 200240, China.
authors: Weizheng
authors: W
authors: Fan
authors: Wanfang
authors: W
authors: Li
authors: Xin
authors: X
authors: Ma
authors: Xiaoming
authors: X
authors: Tao
authors: Xiaoming
authors: X
authors: Li
authors: Ying
authors: Y
authors: Yao
authors: Xiaomin
authors: X
authors: Xie
authors: Zhaoguo
authors: Z
authors: Zhang