title: Prevention of visually debilitating deposits on soft contact lenses in keratoprosthesis patients.
abstract: OBJECTIVE
  To describe visually debilitating deposit formation on hydrogel contact lenses routinely used for protection in eyes with keratoprosthesis and to present different types of contact lenses that provide improved deposit resistance.
  
  
  METHODS
  Seven keratoprosthesis eyes with a history of rapid and severe deposit formation on their hydrogel lenses were evaluated and documented. The Schirmer values and blink rate of each patient were additionally analyzed. These patients were then subsequently refitted with varying types of contact lenses.
  
  
  RESULTS
  When soft hydrogel lenses were replaced with lenses with water-impermeable centers, dramatically fewer deposits accumulated. Deposit formation on hydrogel lenses did not seem to correlate with low Schirmer values but rather with an insufficient blink rate.
  
  
  CONCLUSIONS
  Excellent deposit resistance can be achieved in these patients with the use of hybrid contact lenses with rigid centers or large-diameter entirely rigid contact lenses.
authors: Contact Lens Department, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA 02114, USA. jill_beyer@meei.harvard.edu
authors: Jill
authors: J
authors: Beyer
authors: Amit
authors: A
authors: Todani
authors: Claes
authors: C
authors: Dohlman
mesh_terms: D000328:Adult; D000368:Aged; D001187:Artificial Organs; D001767:Blinking; D003263:Contact Lenses, Hydrophilic / Q000009:adverse effects*; D003315:Cornea; D003316:Corneal Diseases / Q000378:metabolism / Q000628:therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D017060:Patient Satisfaction; D013666:Tears / Q000378:metabolism