title: Synthesis of the disialic acid-embedded glycan part of ganglioside HPG-1.
abstract: Synthesis of tetrasaccharide portion of ganglioside HPG-1 is described. The tetrasaccharide sequence, Fuc-α(1,8)-Neu5Gc-α(2,4)-Neu5Ac-α(2,6)-Glc, was successfully assembled by a linear strategy, in which the 1,5-lactamized sialyl galactose acceptor and the 8-O-Lev-N-Troc-sialic acid donor were exploited as key units.
authors: Department of Applied Bio-Organic Chemistry, Gifu University, Gifu, Japan.
authors: Hiroyo
authors: H
authors: Shimizu
authors: Yuki
authors: Y
authors: Iwayama
authors: Akihiro
authors: A
authors: Imamura
authors: Hiromune
authors: H
authors: Ando
authors: Hideharu
authors: H
authors: Ishida
authors: Makoto
authors: M
authors: Kiso
mesh_terms: D002240:Carbohydrate Sequence; D060326:Chemistry Techniques, Synthetic / Q000379:methods*; D005732:Gangliosides / Q000737:chemistry*; D008969:Molecular Sequence Data; D019158:N-Acetylneuraminic Acid / Q000737:chemistry*; D011134:Polysaccharides / Q000138:chemical synthesis* / Q000737:chemistry*
chemical_list: D005732:Gangliosides; D011134:Polysaccharides; D019158:N-Acetylneuraminic Acid