title: Sudden death from systemic rotavirus infection and detection of nonstructural rotavirus proteins.
abstract: A 2.5-year-old girl died suddenly during the course of rotavirus gastroenteritis. The autopsy showed encephalopathy with rotavirus systemic infection. Here, we provide evidence of rotavirus replication in multiple organs. Our findings clarify that rotavirus infection in children can extend beyond the intestinal tract through viremia.
authors: Kyoto Min-iren Chuo Hospital, 16-1 Nishinokyo-Kasuga-cho, Nakagyo-ku, Kyoto 604-8453, Japan. inekoto@E-mail.jp
authors: Ineko
authors: I
authors: Nakano
authors: Koki
authors: K
authors: Taniguchi
authors: Hatsue
authors: H
authors: Ishibashi-Ueda
authors: Yoshimasa
authors: Y
authors: Maeno
authors: Naoki
authors: N
authors: Yamamoto
authors: Akiko
authors: A
authors: Yui
authors: Satoshi
authors: S
authors: Komoto
authors: Yasushi
authors: Y
authors: Wakata
authors: Tamehito
authors: T
authors: Matsubara
authors: Nozomu
authors: N
authors: Ozaki
mesh_terms: D001921:Brain / Q000473:pathology / Q000821:virology; D002675:Child, Preschool; D003645:Death, Sudden / Q000209:etiology*; D018792:Encephalitis, Viral / Q000175:diagnosis* / Q000473:pathology / Q000821:virology; D005260:Female; D005759:Gastroenteritis / Q000150:complications / Q000175:diagnosis* / Q000821:virology; D006321:Heart / Q000821:virology; D006651:Histocytochemistry; D006801:Humans; D007150:Immunohistochemistry; D007422:Intestines / Q000473:pathology / Q000821:virology; D008099:Liver / Q000473:pathology / Q000821:virology; D008853:Microscopy; D009206:Myocardium / Q000473:pathology; D012401:Rotavirus / Q000302:isolation & purification*; D012400:Rotavirus Infections / Q000175:diagnosis* / Q000473:pathology / Q000821:virology; D017361:Viral Nonstructural Proteins / Q000032:analysis*
chemical_list: D017361:Viral Nonstructural Proteins