title: [Risk factors for recurrence of stage II colon cancer].
abstract: OBJECTIVE
  This study was designed to clarify risk factors for the recurrence of stage II colon cancer in patients and to determine possible treatment options for postoperative adjuvant chemotherapy.
  
  
  METHODS
  The subjects were 132 patients with stage II colon cancer who underwent surgery in this department from January 1998 to December 2007. Various high risk factors for recurrence and factors indicative of poor prognosis were examined (age, gender, site of tumor, maximum tumor diameter, invasion depth, histopathological classification, D number, ly, v, number of biopsied lymph nodes, preoperative tumor marker values and presence of postoperative adjuvant therapy).
  
  
  RESULTS
  The group with postoperative adjuvant therapy had a better prognosis than the others (p=0. 0168). Groups with an absence of postoperative adjuvant therapy (p=0. 041), presence of vessel involvement (p=0. 0127), and poorly-differentiated types (p=0. 027)were extracted in a multivariate analysis of risk factors for recurrence.
  
  
  CONCLUSIONS
  Postoperative adjuvant therapy was effective for stage II colon cancer. Vessel involvement and poorly-differentiated types were risk factors for recurrence of stage II colon cancer.
authors: Department of Surgery, Kakogawa Municipal Hospital, Japan.
authors: Yoshiki
authors: Y
authors: Okamoto
authors: Takashi
authors: T
authors: Kawamura
authors: Tetsuya
authors: T
authors: Sakai
authors: Masaaki
authors: M
authors: Mitsutsuji
authors: Taro
authors: T
authors: Oshikiri
authors: Yasuhisa
authors: Y
authors: Kamoda
authors: Nobunao
authors: N
authors: Takase
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000970:Antineoplastic Agents / Q000627:therapeutic use; D003110:Colonic Neoplasms / Q000098:blood supply / Q000188:drug therapy / Q000473:pathology*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D012008:Recurrence; D012189:Retrospective Studies; D012307:Risk Factors
chemical_list: D000970:Antineoplastic Agents