title: The application of magnetic resonance imaging in preoperative evaluation of patients with endometrial carcinoma.
abstract: OBJECTIVE
  The aim of this paper was to assess the usefulness of the preoperative application of magnetic resonance (MRI) imaging in patients with confirmed endometrial carcinoma.
  
  
  METHODS
  This prospective study included 50 patients with endometrial cancer. MRI was used for preoperative disease staging and in planning the operative treatment. The parameters monitored by MRI were compared with the findings of curettage pathological examination. Estimated were the depth of myometrial invasion, the involvement of the cervix by the tumor, the presence of adnexal metastases and regional lymph nodes. Sensitivity, specificity, positive (PPV) and negative predictive value (NPV) of the MRI in relation to the aforementioned clinicopathological parameters were assessed.
  
  
  RESULTS
  The presence of myometrial invasion was estimated with 100% specificity, 86% sensitivity, 100% PPV and 40% NPV. The estimation of the depth of myometrial invasion (>or<50%) was defined with 89% sensitivity, 54% specificity, 83% PPV and 60% NPV. MRI provided valuable data about cervical invasion (100% PPV for the presence of cervical invasion and 55% PPV for the depth of cervical invasion), thereby helping to decide on the kind of surgical intervention, the choice of approach (open or laparoscopic surgery) and the choice of the surgeon.
  
  
  CONCLUSIONS
  MRI is useful and reliable in preoperative evaluation. The information obtained by MRI provides space and time for planning the treatment modality.
authors: Clinic of Obstetrics and Gynecology, Nis Clinical Center, Nis, Serbia. sanja.petric@hotmail.com
authors: A
authors: A
authors: Petric
authors: D
authors: D
authors: Stojanov
authors: V
authors: V
authors: Lilic
authors: S
authors: S
authors: Filipovic
authors: P
authors: P
authors: Bosnjakovic
authors: R
authors: R
authors: Zivadinovic
authors: G
authors: G
authors: Lilic
authors: I
authors: I
authors: Todorovska
authors: S
authors: S
authors: Vrbic
authors: I
authors: I
authors: Pejcic
mesh_terms: D000328:Adult; D000368:Aged; D002584:Cervix Uteri / Q000473:pathology; D016889:Endometrial Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008875:Middle Aged; D009215:Myometrium / Q000473:pathology; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D057234:Preoperative Period; D011446:Prospective Studies