title: Cerebral venous sinus thrombosis in Saudi Arabia.
abstract: OBJECTIVE
  To analyze the clinical patterns, etiologies, treatment, and outcome of cerebral venous sinus thrombosis (CVST) in 2 major cities of Saudi Arabia, Jeddah and Al-Baha.
  
  
  METHODS
  One hundred and eleven patients diagnosed as CVST were identified from the medical records at King Abdulaziz Medical City, Jeddah, and King Fahad Hospital, Al-Baha, Saudi Arabia, from January 1990 through November 2010. We retrospectively analyzed the data, compared it with local and international studies, and reviewed the literature.
  
  
  RESULTS
  There were 92 adults and 19 children. Among adults, females predominated, while more boys were affected than girls. The mean age of onset was 29.5 years. The most common clinical presentations were headache, focal neurologic deficits, seizures, papilledema, and decreased level of consciousness. The main risk factors identified were pregnancy/ puerperium, antiphospholipid antibody syndrome, oral contraceptive pills, malignancy, and infections. Multiple sinuses were affected in 51 patients (45.9%). When a single sinus was involved, the superior sagittal sinus (24.3%) was the most common. Seventy-four patients recovered completely, 23 patients recovered partially, and 10 patients died. Bad prognostic factors included incurable co-morbid conditions, late presentation, and status epilepticus.
  
  
  CONCLUSIONS
  Pregnancy/puerperium was the most common etiological factor in our series. Clinical features were similar to international series. Behcet`s disease was not a major etiological factor in our series. Most patients had involvement of multiple sinuses. Prompt treatment with anticoagulation resulted in complete or partial recovery in 87.4% of patients.
authors: Department of Medicine, King Abdulaziz Medical City, Jeddah 21483, Kingdom of Saudi Arabia. halgahtani@hotmail.com
authors: Hussein A
authors: HA
authors: Algahtani
authors: Abduljaleel P
authors: AP
authors: Abdu
authors: Abdulrahman M
authors: AM
authors: Shami
authors: Ayman E
authors: AE
authors: Hassan
authors: Moustafa A
authors: MA
authors: Madkour
authors: Saeed M
authors: SM
authors: Al-Ghamdi
authors: Ravi M
authors: RM
authors: Malhotra
authors: Ali M
authors: AM
authors: Al-Khathami
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D003392:Cranial Sinuses / Q000473:pathology / Q000503:physiopathology*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D011247:Pregnancy; D012189:Retrospective Studies; D012529:Saudi Arabia / Q000453:epidemiology; D012851:Sinus Thrombosis, Intracranial / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology*; D055815:Young Adult