title: Giant stomach secondary to juvenile polyposis syndrome.
abstract: BACKGROUND
  Juvenile polyposis syndrome (JPS) is a rare, autosomal dominant condition. The polyps predominate in the colon but may be seen less commonly in the stomach or small intestine. We report an unusual case of JPS associated with massive gastric polyposis, resulting in a giant stomach, severe anemia, hematemesis, protein-losing enteropathy, and gastric outlet obstruction. Progressive complications ultimately necessitated a total gastrectomy.
  
  
  METHODS
  A 27-year-old woman presented in 2005 with severe anemia. Gastroscopy revealed severe gastric polyposis. Histopathology confirmed juvenile polyposis. Gastrectomy was initially declined. Progressive hematemesis, hypoproteinemia, and gastric outlet obstruction, however, resulted in a total gastrectomy 5 years following initial presentation. Massive gastric polyposis resulted in severe gastromegaly.
authors: Department of Surgery, Mount Sinai Hospital, 600 University Avenue, Suite 1225, Toronto, ON, M5G 1X5, Canada.
authors: Nathalie
authors: N
authors: Wong-Chong
authors: Wondwossen Hailu
authors: WH
authors: Kidanewold
authors: Richard
authors: R
authors: Kirsch
authors: Gary Robert
authors: GR
authors: May
authors: Judith Andrea
authors: JA
authors: McCart
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D005743:Gastrectomy; D005773:Gastroscopy; D006801:Humans; D044483:Intestinal Polyposis / Q000150:complications / Q000151:congenital* / Q000175:diagnosis; D009386:Neoplastic Syndromes, Hereditary; D013272:Stomach Diseases / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery