title: Enzyme electrode for aromatic compounds exploiting the catalytic activities of microperoxidase-11.
abstract: Microperoxidase-11 (MP-11) which has been immobilised in a matrix of chitosan-embedded gold nanoparticles on the surface of a glassy carbon electrode catalyzes the conversion of aromatic substances. This peroxide-dependent catalysis of microperoxidase has been applied in an enzyme electrode for the first time to indicate aromatic compounds such as aniline, 4-fluoroaniline, catechol and p-aminophenol. The electrode signal is generated by the cathodic reduction of the quinone or quinoneimine which is formed in the presence of both MP-11 and peroxide from the substrate. The same sensor principle will be extended to aromatic drugs.
authors: Fraunhofer Institute for Biomedical Engineering IBMT, D-14476 Potsdam, Germany.
authors: Aysu
authors: A
authors: Yarman
authors: Artavazd
authors: A
authors: Badalyan
authors: Nenad
authors: N
authors: Gajovic-Eichelmann
authors: Ulla
authors: U
authors: Wollenberger
authors: Frieder W
authors: FW
authors: Scheller
mesh_terms: D015374:Biosensing Techniques / Q000295:instrumentation*; D002384:Catalysis; D003217:Conductometry / Q000295:instrumentation*; D004789:Enzyme Activation; D004800:Enzymes, Immobilized / Q000737:chemistry; D004867:Equipment Design; D019544:Equipment Failure Analysis; D006841:Hydrocarbons, Aromatic / Q000032:analysis*; D009842:Oligopeptides / Q000737:chemistry*
chemical_list: D004800:Enzymes, Immobilized; D006841:Hydrocarbons, Aromatic; C067309:MP 11; D009842:Oligopeptides