title: A new proposal for a clinical-oriented subclassification of baboon syndrome and a review of baboon syndrome.
abstract: OBJECTIVE
  To review baboon syndrome (BS).
  
  
  METHODS
  Date sources were obtained from PubMed and Google Scholar: Photographs of baboon syndrome were obtained from our patient.
  
  
  METHODS
  PubMed and Google Scholar were searched up to June 30, 2010. The search terms were "baboon syndrome", "SDRIFE" and "thimerosal allergy". Reverse references from relevant articles and Google Scholar were also used. As BS is a classical disease and cases of offending agents were relatively old, some references were more than five years old. In order to gather as many cases of offending agents as possible, more than 50 references were collected.
  
  
  CONCLUSIONS
  We divided BS into as 4 groups; classical baboon syndrome, topical drug-induced baboon syndrome, systemic drug-induced baboon syndrome and symmetrical drug-related intertriginous and flexural exanthema (SDRIFE). The pathomechanism of BS is still unknown. A delayed type of hypersensitivity reaction, a recall phenomenon, pharmacologic interaction with immune-receptors and anatomical factors may be involved in the causation of BS.
authors: Department of Pediatrics, Tokyo Medical University. miyahara.pediatrics@gmail.com
authors: Atsushi
authors: A
authors: Miyahara
authors: Hisashi
authors: H
authors: Kawashima
authors: Yukari
authors: Y
authors: Okubo
authors: Akinori
authors: A
authors: Hoshika
mesh_terms: D003937:Diagnosis, Differential; D003875:Drug Eruptions / Q000145:classification* / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology; D004781:Environmental Exposure / Q000009:adverse effects; D004890:Erythema; D006801:Humans; D006968:Hypersensitivity, Delayed; D007156:Immunologic Memory; D008628:Mercury / Q000009:adverse effects*; D011310:Preservatives, Pharmaceutical / Q000009:adverse effects*; D012307:Risk Factors; D013577:Syndrome; D013849:Thimerosal / Q000009:adverse effects*
chemical_list: D011310:Preservatives, Pharmaceutical; D013849:Thimerosal; D008628:Mercury