title: The effect of transient proanthocyanidins preconditioning on the cross-linking and mechanical properties of demineralized dentin.
abstract: Proanthocyanidin-based preconditioners were prepared by adding powdered proanthocyanidins-rich grape seed extract to various solvents at different concentrations. Demineralized dentin specimens were preconditioned for 20, 30, 60 or 120 s, followed by the evaluation of their cross-linking degree, mechanical properties and micromorphology. The cross-linking degree of the demineralized dentin collagen exhibited concentration- and time- dependent increase after preconditioning treatment, irrespective of the preconditioner and the solvent. When treated for the same exposure time, specimens after 15% proanthocyanidins preconditioning resulted in the highest mean ultimate tensile strength compared with all the other groups tested. Five percent glutaraldehyde control group produced the highest cross-linking degree, but the ultimate tensile strength was lower than that of 15% proanthocyanidins group. The field emission scanning electron microscopy confirmed that the demineralized dentin collagen was in a homogeneous and regular arrangement after preconditioning and maintained expanding, regardless of the surface moisture conditions.
authors: Department of Prosthodontics, School of Stomatology, Fourth Military Medical University, #145 Changle Xi Road, 710032 Xi'an, People's Republic of China.
authors: Ruirui
authors: R
authors: Liu
authors: Ming
authors: M
authors: Fang
authors: Yuhong
authors: Y
authors: Xiao
authors: Fang
authors: F
authors: Li
authors: Lan
authors: L
authors: Yu
authors: Sanjun
authors: S
authors: Zhao
authors: Lijuan
authors: L
authors: Shen
authors: Jihua
authors: J
authors: Chen
mesh_terms: D001696:Biomechanical Phenomena; D003804:Dentin / Q000737:chemistry*; D049672:History, 19th Century; D006801:Humans; D044945:Proanthocyanidins / Q000737:chemistry*; D013718:Tensile Strength; D014070:Tooth / Q000737:chemistry
chemical_list: D044945:Proanthocyanidins