title: Post-operative ocular infection due to Streptococcus dysgalactiae subspecies equisimilis.
abstract: Ocular infections due to Streptococcus dysgalactiae subsp. equisimilis are rare. In the present report, three patients with a history of uncomplicated small incision cataract surgery with intraocular lens implantation developed exogenous endophthalmitis due to Streptococcus dysgalactiae subsp. equisimilis. The identification of the organisms was confirmed by PCR for a 16S rRNA sequence specific to the species S. dysgalactiae. Intravitreal treatment of cefazolin and amikacin, in addition to topical ofloxacin and tobramycin, resulted in resolution of infection in all three patients. Our reports indicate the importance of bacterial culture and molecular identification in the diagnosis of S. dysgalactiae subsp. equisimilis infection in the eye.
authors: Department of Ocular Microbiology, Institute of Ophthalmology, Joseph Eye Hospital, Trichy - 620001, Tamilnadu, India. kaliaj17@gmail.com
authors: Jayaraman
authors: J
authors: Kaliamurthy
authors: Vincenzo
authors: V
authors: Cuteri
authors: Nelson
authors: N
authors: Jesudasen
authors: Amjad
authors: A
authors: Salman
authors: Philip A
authors: PA
authors: Thomas
authors: Silvia
authors: S
authors: Preziuso
mesh_terms: D000368:Aged; D000583:Amikacin / Q000008:administration & dosage; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D002387:Cataract Extraction / Q000009:adverse effects; D002437:Cefazolin / Q000008:administration & dosage; D004269:DNA, Bacterial / Q000737:chemistry / Q000235:genetics; D004275:DNA, Ribosomal / Q000737:chemistry / Q000235:genetics; D009877:Endophthalmitis / Q000382:microbiology* / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008969:Molecular Sequence Data; D012336:RNA, Ribosomal, 16S / Q000235:genetics; D017422:Sequence Analysis, DNA; D013290:Streptococcal Infections / Q000175:diagnosis* / Q000473:pathology*; D013291:Streptococcus / Q000145:classification / Q000302:isolation & purification*; D013530:Surgical Wound Infection / Q000382:microbiology* / Q000473:pathology*; D014031:Tobramycin / Q000008:administration & dosage; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D004269:DNA, Bacterial; D004275:DNA, Ribosomal; D012336:RNA, Ribosomal, 16S; D000583:Amikacin; D002437:Cefazolin; D014031:Tobramycin