title: Uveitis preceding Crohn's disease by 8 years.
abstract: We report the clinical history of a child affected by Crohn's disease in which uveitis precedes intestinal involvement by years and occurs with the atypical features of anterior chronic inflammation complicated by unilateral optic disc edema, rather than recurrent anterior uveitis with sudden onset which has been more widely reported in inflammatory bowel diseases. The uveitis onset occurred 8 years before symptoms of the primary intestinal disease, while in inflammatory bowel diseases the intestinal inflammation typically precedes ocular symptoms, and ocular inflammation only occasionally precedes inflammatory involvement of the bowel.
authors: Ocular Immunovirology Service, Department of Ophthalmology, Sapienza University of Rome, V.le del Policlinico 155, 00161, Rome, Italy. mpparoli@tiscali.it
authors: Maria Pia
authors: MP
authors: Paroli
authors: Giovanni
authors: G
authors: Spinucci
authors: Alice
authors: A
authors: Bruscolini
authors: Maurizio
authors: M
authors: La Cava
authors: Irene
authors: I
authors: Abicca
mesh_terms: D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D001379:Azathioprine / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D003424:Crohn Disease / Q000175:diagnosis* / Q000188:drug therapy; D004359:Drug Therapy, Combination; D016099:Endoscopy, Gastrointestinal; D006801:Humans; D008297:Male; D008853:Microscopy; D010211:Papilledema / Q000175:diagnosis; D012460:Sulfasalazine / Q000627:therapeutic use; D013997:Time Factors; D014606:Uveitis, Anterior / Q000175:diagnosis* / Q000601:surgery; D014792:Visual Acuity / Q000502:physiology; D014821:Vitrectomy
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D012460:Sulfasalazine; D001379:Azathioprine