title: Small but smart--microRNAs in the centre of inflammatory processes during cardiovascular diseases, the metabolic syndrome, and ageing.
abstract: With a progressively growing elderly population, ageing-associated pathologies such as cardiovascular diseases are becoming an increasing economic, social, and personal burden for Western societies. Interestingly, all ageing-associated diseases share a common denominator: inflammation. Recently, microRNAs were shown to be implicated in the full range of processes of ageing, inflammation, and cardiovascular diseases. This review focuses on their role in cardiovascular diseases with emphasis on their implication in the inflammatory processes that accompany heart failure, atherosclerosis, coronary artery disease, and finally obesity and diabetes as components of the ageing-associated metabolic syndrome.
authors: Center for Heart Failure Research, Cardiovascular Research Institute Maastricht,  Maastricht University, Universiteitssingel 50, Maastricht 6229 ER,  The Netherlands.
authors: Blanche
authors: B
authors: Schroen
authors: Stephane
authors: S
authors: Heymans
mesh_terms: D000375:Aging / Q000502:physiology*; D000818:Animals; D002318:Cardiovascular Diseases / Q000503:physiopathology*; D003920:Diabetes Mellitus / Q000503:physiopathology; D004195:Disease Models, Animal; D006801:Humans; D007249:Inflammation / Q000503:physiopathology*; D024821:Metabolic Syndrome / Q000503:physiopathology*; D035683:MicroRNAs / Q000502:physiology*; D009765:Obesity / Q000503:physiopathology
chemical_list: D035683:MicroRNAs