title: Primary spontaneous pneumothorax and mitral valve prolapse are not associated.
abstract: BACKGROUND
  Mitral valve prolapse (MVP) is a common diagnosis in patients with primary spontaneous pneumothorax (PSP). This description assumes that MVP and PSP might be manifestations of a systemic connective tissue abnormality. The purpose of this study was to determine the prevalence of MVP in PSP patients of Croatian origin and evaluate their relationship with connective tissue disorders. We also examined the prevalence of PSP in patients with primary MVP.
  
  
  METHODS
  Thirty-two patients with PSP and without underlying pulmonary disease or connective tissue disease underwent two-dimensional transthoracic echocardiography performed by a certified cardiologist. Echocardiography and demographic features were analyzed using descriptive statistics. We also examined the medical records of 60 patients with primary MVP.
  
  
  RESULTS
  MVP was found in none of the 32 patients suffering from PSP. The age, sex, smoking status, body mass index, side, rate, and family history were similar to previous investigations. Likewise, none of the 60 patients with primary MVP ever had PSP.
  
  
  CONCLUSIONS
  By applying an updated definition of MVP, we found no MVP case among PSP patients of Croatian origin. We also found no PSP in the primary MVP group. Ethnicity may influence the occurrence of MVP in PSP patients, and PSP in primary MVP patients.
authors: Department of Pulmonology, University Hospital Rijeka, Rijeka, Croatia. veljko.flego2@ri.t-com.hr
authors: Veljko
authors: V
authors: Flego
authors: Dubravka Matanic
authors: DM
authors: Lender
authors: Igor
authors: I
authors: Barkovic
authors: Ljiljana
authors: L
authors: Bulat-Kardum
authors: Teodora
authors: T
authors: Zaninovic Jurjevic
authors: Zeljka
authors: Z
authors: Diklic
authors: Milan
authors: M
authors: Niksic
authors: Ante
authors: A
authors: Matana
authors: Luka
authors: L
authors: Zaputovic
mesh_terms: D000328:Adult; D015984:Causality; D015897:Comorbidity; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008945:Mitral Valve Prolapse / Q000000981:diagnostic imaging* / Q000453:epidemiology*; D011030:Pneumothorax / Q000000981:diagnostic imaging* / Q000453:epidemiology*; D015995:Prevalence; D018570:Risk Assessment; D012307:Risk Factors; D017678:Sex Distribution; D014463:Ultrasonography; D055815:Young Adult