title: Estrogens and obesity: is it all in our heads?
abstract: Estrogens have preventative effects on weight gain and associated comorbidities, but the tissue-specific targets remain unknown. Here, Xu et al. (2011) demonstrate that ablation of estrogen signaling in two populations of hypothalamic neurons leads to weight gain and subsequent metabolic dysregulation and could be important target sites of estrogen actions.
authors: Pediatric Endocrinology, Duke University Medical Center, Durham, NC 27710, USA.
authors: Sarah
authors: S
authors: Hart-Unger
authors: Kenneth S
authors: KS
authors: Korach