title: The influence of perforating the autogenous block bone and the recipient bed in dogs. Part I: a radiographic analysis.
abstract: OBJECTIVE
  This study evaluated radiographically the integration and volume maintenance of grafted autogenous block bone under various cortical bone perforation conditions in dogs.
  
  
  METHODS
  Five mongrel dogs were used. Each dog received four differently prepared onlay block bone grafts: a solid block graft was fixed on either (1) a cortically perforated recipient bed (SGPR) or (2) a nonperforated recipient bed (SGNPR), a perforated block graft was fixed on either (3) a nonperforated recipient bed (PGNPR) or (4) a cortically perforated recipient bed (PGPR). The animals were sacrificed at 1 day, 4 days, 10 days, 4 weeks, and 8 weeks after surgery. Specimens were prepared and radiographic analysis was conducted by using micro-computed tomography. The residual bone volume (RBV; mm(3) ), cross-sectional bone area (BA; mm(2)), and residual height (RH; %) of the grafted block bone were measured radiographically.
  
  
  RESULTS
  The interface between the recipient bed and the graft showed no signs of bone integration at 1, 4, and 10 days of healing. However, at 4 weeks of healing, bone integration was observed in all groups. The RBV, BA, and RH of the grafts gradually decreased by 4 weeks of healing. At 8 weeks, the PGPR condition exhibited a higher RBV, BA, and RH than the other conditions, whereas the SGNPR condition exhibited the lowest RBV, BA, and RH.
  
  
  CONCLUSIONS
  Within the limitations of this study, it can be concluded that intentional cortical perforation on the recipient bed and block bone graft may influence volume maintenance of the graft.
authors: Department of Periodontology, Research Institute for Periodontal Regeneration, College of Dentistry, Yonsei University, Seoul, South Korea.
authors: Kyung-Choon
authors: KC
authors: Oh
authors: Jae-Kook
authors: JK
authors: Cha
authors: Chang-Sung
authors: CS
authors: Kim
authors: Seong-Ho
authors: SH
authors: Choi
authors: Jung-Kiu
authors: JK
authors: Chai
authors: Ui-Won
authors: UW
authors: Jung
mesh_terms: D019412:Anatomy, Cross-Sectional; D000818:Animals; D001862:Bone Resorption / Q000145:classification / Q000000981:diagnostic imaging; D016025:Bone Transplantation / Q000000981:diagnostic imaging / Q000379:methods*; D004285:Dogs; D006085:Graft Survival; D007091:Image Processing, Computer-Assisted / Q000379:methods; D021621:Imaging, Three-Dimensional / Q000379:methods; D008297:Male; D008437:Maxilla / Q000000981:diagnostic imaging / Q000601:surgery*; D009929:Organ Size; D010012:Osteogenesis / Q000502:physiology; D010027:Osteotomy / Q000379:methods; D011897:Random Allocation; D013997:Time Factors; D020858:Tissue and Organ Harvesting / Q000379:methods; D014182:Transplantation, Autologous; D014945:Wound Healing / Q000502:physiology; D055114:X-Ray Microtomography