title: [Study on antioxidant effect and chemical constituents of taohong siwu decoction].
abstract: OBJECTIVE
  To evaluate the antioxidant effects of Taohong Siwu decoction and to exploit the bioactive constituents.
  
  
  METHODS
  The samples were prepared by macroporous adsorptive resins (TH-1-TH-15). Three antioxidant models were adopted to evaluate the antioxidant activities of Taohong Siwu decoction and its different separated fractions in vitro. It was found that fractions (TH-2, TH-4, TH-7, TH-8, TH-9), separated from Taohong Siwu decoction, mainly contributed to the antioxidant effects. The chemical constituents in the most active fraction TH-8 were identified and determined by HPLC.
  
  
  RESULTS
  TH-8 showed significant antioxidant activities in the antioxidant experiments. Six compounds in the fraction were determined which were amygdalin, albiflorin, paeoniflorin, benzoic acid, coumaric acid and ferulic acid. The contents were 75.70, 31.26, 60.79, 1.196, 1.108, 4.861 mg L(-1), respectively.
  
  
  CONCLUSIONS
  Glycosides and aromatic acids may be the principle effective constituents in the active fraction.
authors: Jiangsu Key Laboratory for Traditional Chinese Medicine Formulae Research, Nanjing University of Chinese Medicine, Nanjing 210046, China.
authors: Li
authors: L
authors: Liu
authors: Jin'ao
authors: J
authors: Duan
authors: Yuping
authors: Y
authors: Tang
authors: Hongyue
authors: H
authors: Ma
authors: Shulan
authors: S
authors: Su
authors: Xiaoxi
authors: X
authors: Li
mesh_terms: D000975:Antioxidants / Q000737:chemistry*; D004365:Drugs, Chinese Herbal / Q000737:chemistry*
chemical_list: D000975:Antioxidants; D004365:Drugs, Chinese Herbal