title: A novel route to copper(II) detection using 'click' chemistry-induced aggregation of gold nanoparticles.
abstract: A simple colorimetric method for the detection of copper ions in water is described. This method is based on the 'click' copper(I)-catalyzed azide-alkyne cycloaddition reaction and its use in promoting the aggregation of azide-tagged gold nanoparticles by a dialkyne cross-linker is described. Nanoparticle cross-linking, evidenced as a colour change, is used for the detection of copper ions. The lowest detected concentration by the naked eye was 1.8 μM, with the response linear with log(concentration) between 1.8-200 μM. The selectivity relative to other potentially interfering ions was evaluated.
authors: School of Chemistry, The University of New South Wales, Sydney, NSW 2052, Australia.
authors: Carol
authors: C
authors: Hua
authors: William H
authors: WH
authors: Zhang
authors: Swahnnya R M
authors: SR
authors: De Almeida
authors: Simone
authors: S
authors: Ciampi
authors: Danmar
authors: D
authors: Gloria
authors: Guozhen
authors: G
authors: Liu
authors: Jason B
authors: JB
authors: Harper
authors: J Justin
authors: JJ
authors: Gooding
mesh_terms: D000480:Alkynes / Q000737:chemistry; D001386:Azides / Q000737:chemistry; D015374:Biosensing Techniques / Q000295:instrumentation / Q000379:methods*; D002384:Catalysis; D002413:Cations, Divalent / Q000032:analysis; D057930:Click Chemistry / Q000295:instrumentation / Q000379:methods*; D003124:Colorimetry / Q000379:methods; D003300:Copper / Q000032:analysis*; D003432:Cross-Linking Reagents / Q000737:chemistry; D003500:Cyclization; D006046:Gold / Q000737:chemistry*; D057230:Limit of Detection; D053768:Metal Nanoparticles / Q000737:chemistry*; D008855:Microscopy, Electron, Scanning / Q000379:methods; D014881:Water Supply / Q000032:analysis / Q000592:standards
chemical_list: D000480:Alkynes; D001386:Azides; D002413:Cations, Divalent; D003432:Cross-Linking Reagents; D006046:Gold; D003300:Copper