title: Case study and review: treatment of tricuspid prosthetic valve thrombosis.
abstract: Prosthetic valve thrombosis (PVT) is a severe and life-threatening complication of heart valve replacement. Conventional therapy is surgical thrombectomy or valve replacement. Medical thrombolysis is another emerging option. We report the case of a 57 year old woman with a history of Ebstein anomaly who underwent successful treatment of tricuspid prosthetic valve thrombosis with intra-atrial infusion of very low dose recombinant tissue plasminogen activator (tPA). We review the presentation, etiology, diagnosis, and treatment of tricuspid PVT emphasizing a modified medical option as a safe, minimally invasive alternative to surgical intervention or conventional medical therapy for tricuspid valve thrombosis.
authors: Division of Internal Medicine, University of Miami Miller School of Medicine, Miami, FL, USA.
authors: David Yi
authors: DY
authors: Zhang
authors: Jay
authors: J
authors: Lozier
authors: Richard
authors: R
authors: Chang
authors: Vandana
authors: V
authors: Sachdev
authors: Marcus Y
authors: MY
authors: Chen
authors: Jennifer L
authors: JL
authors: Audibert
authors: Keith A
authors: KA
authors: Horvath
authors: Douglas R
authors: DR
authors: Rosing
mesh_terms: D005260:Female; D006350:Heart Valve Prosthesis / Q000009:adverse effects*; D006801:Humans; D008875:Middle Aged; D015912:Thrombolytic Therapy; D013927:Thrombosis / Q000188:drug therapy / Q000209:etiology*; D014261:Tricuspid Valve / Q000601:surgery*