title: Lanostane and hopane triterpenes from the entomopathogenic fungus Hypocrella sp. BCC 14524.
abstract: Seven new lanostane-type triterpenes, hypocrellols A-G (1-7), and six new hopane-type triterpenes, 7β,15α-dihydroxy-22(29)-hopene (8), 3β,7β-dihydroxy-22(29)-hopene (9), 3β-acetoxy-15α-hydroxy-22(29)-hopene (10), 3β,7β,15α,22-tetrahydroxyhopane (11), 3β-acetoxy-7β,15α,22-trihydroxyhopane (12), and 7β,15α,22-trihydroxyhopane (13), were isolated from the scale insect pathogenic fungus Hypocrella sp. BCC 14524. The structures of the new compounds were elucidated by analyses of the NMR spectroscopic and mass spectrometry data. The structure of 1 was confirmed by X-ray crystallography.
authors: National Center for Genetic Engineering and Biotechnology (BIOTEC), 113 Thailand Science Park, Phaholyothin Road, Klong Luang, Pathumthani 12120, Thailand. isaka@biotec.or.th
authors: Masahiko
authors: M
authors: Isaka
authors: Panida
authors: P
authors: Chinthanom
authors: Malipan
authors: M
authors: Sappan
authors: Rungtiwa
authors: R
authors: Chanthaket
authors: J Jennifer
authors: JJ
authors: Luangsa-ard
authors: Samran
authors: S
authors: Prabpai
authors: Palangpon
authors: P
authors: Kongsaeree
mesh_terms: D000818:Animals; D000962:Antimalarials / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D000970:Antineoplastic Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D000995:Antitubercular Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D002522:Chlorocebus aethiops; D018360:Crystallography, X-Ray; D004351:Drug Resistance; D004354:Drug Screening Assays, Antitumor; D006999:Hypocreales / Q000737:chemistry*; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D009169:Mycobacterium tuberculosis / Q000187:drug effects; D019906:Nuclear Magnetic Resonance, Biomolecular; D010963:Plasmodium falciparum / Q000187:drug effects; D013237:Stereoisomerism; D013785:Thailand; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D014709:Vero Cells
chemical_list: D000962:Antimalarials; D000970:Antineoplastic Agents; D000995:Antitubercular Agents; D014315:Triterpenes; C025206:hopane