title: Use of administrative claims data for comparative effectiveness research of rheumatoid arthritis treatments.
abstract: Observational studies, particularly those using large administrative claims databases, have become increasingly popular sources of comparative effectiveness or comparative safety research. Studies using claims data often face challenges and criticisms due to the lack of certain clinical information, such as lifestyle risk factors, disease severity, and questionable accuracy of disease diagnoses. A novel, claims-based algorithm to evaluate the clinical effectiveness of rheumatoid arthritis medications has been developed and its performance seems promising, although further validation is needed.
authors: Seo Young
authors: SY
authors: Kim
authors: Daniel H
authors: DH
authors: Solomon
mesh_terms: D000465:Algorithms; D018501:Antirheumatic Agents / Q000627:therapeutic use*; D001172:Arthritis, Rheumatoid / Q000188:drug therapy* / Q000453:epidemiology*; D005260:Female; D006801:Humans; D007345:Insurance Claim Review / Q000592:standards*; D008297:Male; D014493:United States Department of Veterans Affairs / Q000592:standards*
chemical_list: D018501:Antirheumatic Agents