title: Quantitative evaluation of bacteria adherent and in biofilm on single-wall carbon nanotube-coated surfaces.
abstract: Biofilm is a common bacterial lifestyle, and it plays a crucial role in human health, causing biofilm-mediated infections. Recently, to counteract biofilm development, new nano-structured biomaterials have been proposed. However, data about the antibacterial properties of nano-structured surfaces are fragmentary and controversial, and, in particular, the susceptibility of nano-structured materials to colonization and biofilm formation by bacterial pathogens has not been yet thoroughly considered. Here, the ability of the pathogenic Streptococcus mutans and Pseudomonas aeruginosa to adhere and form biofilm on surfaces coated with single-wall carbon nanotubes (SWCNTs) was analyzed. Our results showed that the surfaces of SWCNTs-coated glass beads (SWCNTs-GBs) were colonized at the same extent of uncoated GBs both by S. mutans and P. aeruginosa. In conclusion, our results demonstrate that single wall SWCNTs-coated surfaces are not suitable to counteract bacterial adhesion and biofilm development.
authors: Dipartimento di Sanità Pubblica e Malattie Infettive, Sapienza-Università di Roma, Piazzale A. Moro 5, 00185 Roma, Italy.
authors: Fabrizio
authors: F
authors: Pantanella
authors: Francesca
authors: F
authors: Berlutti
authors: Daniele
authors: D
authors: Passeri
authors: Daniela
authors: D
authors: Sordi
authors: Alessandra
authors: A
authors: Frioni
authors: Tiziana
authors: T
authors: Natalizi
authors: Maria Letizia
authors: ML
authors: Terranova
authors: Marco
authors: M
authors: Rossi
authors: Piera
authors: P
authors: Valenti