title: Changes in the repertoire of natural antibodies caused by immunization with bacterial antigens.
abstract: The repertoire of natural anti-glycan antibodies in naïve chickens and in chickens immunized with bacteria Burkholderia mallei, Burkholderia pseudomallei, and Francisella tularensis as well as with peptides from an outer membrane protein of B. pseudomallei was studied. A relatively restricted pattern of natural antibodies (first of all IgY against bacterial cell wall peptidoglycan fragments, L-Rha, and core N-acetyllactosamine) shrank and, moreover, the level of detectable antibodies decreased as a result of immunization.
authors: Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow.
authors: N V
authors: NV
authors: Shilova
authors: M J
authors: MJ
authors: Navakouski
authors: M
authors: M
authors: Huflejt
authors: A
authors: A
authors: Kuehn
authors: R
authors: R
authors: Grunow
authors: O
authors: O
authors: Blixt
authors: N V
authors: NV
authors: Bovin
mesh_terms: D000818:Animals; D000942:Antigens, Bacterial / Q000276:immunology*; D001425:Bacterial Outer Membrane Proteins / Q000276:immunology; D042726:Burkholderia mallei / Q000276:immunology*; D016957:Burkholderia pseudomallei / Q000276:immunology*; D002240:Carbohydrate Sequence; D002645:Chickens / Q000276:immunology*; D005604:Francisella tularensis / Q000276:immunology*; D007113:Immunity, Innate / Q000276:immunology*; D007114:Immunization / Q000662:veterinary*; D007136:Immunoglobulins / Q000032:analysis; D008969:Molecular Sequence Data
chemical_list: D000942:Antigens, Bacterial; D001425:Bacterial Outer Membrane Proteins; C016512:IgY; D007136:Immunoglobulins