title: Xpert MTB/RIF assay for diagnosis of pleural tuberculosis.
abstract: We prospectively investigated the diagnostic utility of the Xpert MTB/RIF (Mycobacterium tuberculosis/rifampin [RIF] resistance) assay in 20 cases with confirmed tuberculous pleural effusion. The sensitivity and specificity of the Xpert assay in pleural fluid were 25% and 100%, respectively. All cases positive by the Xpert assay were also positive by pleural fluid culture.
authors: Department of Biomedical Sciences, Faculty of Health Sciences, P.O. Box 19063, Tygerberg 7505, South Africa.
authors: Sven O
authors: SO
authors: Friedrich
authors: Florian
authors: F
authors: von Groote-Bidlingmaier
authors: Andreas H
authors: AH
authors: Diacon
mesh_terms: D000995:Antitubercular Agents / Q000494:pharmacology; D001431:Bacteriological Techniques / Q000379:methods*; D024881:Drug Resistance, Bacterial; D006801:Humans; D025202:Molecular Diagnostic Techniques / Q000379:methods*; D009169:Mycobacterium tuberculosis / Q000187:drug effects* / Q000235:genetics / Q000302:isolation & purification*; D011446:Prospective Studies; D012293:Rifampin / Q000494:pharmacology; D012680:Sensitivity and Specificity; D014396:Tuberculosis, Pleural / Q000175:diagnosis* / Q000382:microbiology*
chemical_list: D000995:Antitubercular Agents; D012293:Rifampin