title: Incidence, predictors, and clinical impact of tissue prolapse after coronary intervention: an intravascular optical coherence tomography study.
abstract: OBJECTIVE
  To evaluate the predictors of tissue prolapse after stenting and whether this phenomenon can affect the clinical outcome.
  
  
  METHODS
  All consecutive patients who underwent optical coherence tomography (OCT) examination after stent implantation were included. Qualitative and quantitative assessment of tissue prolapse after stent implantation was performed. The lesions were classified into 4 groups according to the severity of tissue prolapse. We analyzed the clinical, procedural, and image-based predictors of severe tissue prolapse and evaluated the clinical impact of tissue prolapse.
  
  
  RESULTS
  Tissue prolapse within the stented segment was visible in 102/104 (98.08%) cases. The frequency and severity of tissue prolapse was similar in acute coronary syndrome (ACS) and non-ACS lesions. The OCT-defined thin cap fibroatheroma (TCFA) was related with severe tissue prolapse (≥ grade III) (r = 17.722, p < 0.001). No difference in events was observed among different tissue prolapse groups during the hospitalization period and 1-year follow-up.
  
  
  CONCLUSIONS
  The incidence of tissue prolapse after stent implantation was relatively high, irrespective of the clinical presentation. OCT-defined TCFA lesions were more likely with severe tissue prolapse (≥ grade III). Tissue prolapse was not associated with clinical events during the hospitalization period and 1-year clinical follow-up.
authors: Department of Cardiovascular Medicine, Chinese PLA General Hospital, Beijing.
authors: Qin-Hua
authors: QH
authors: Jin
authors: Yun-Dai
authors: YD
authors: Chen
authors: Jing
authors: J
authors: Jing
authors: Feng
authors: F
authors: Tian
authors: Jun
authors: J
authors: Guo
authors: Chang-Fu
authors: CF
authors: Liu
authors: Lian
authors: L
authors: Chen
authors: Zhi-Jun
authors: ZJ
authors: Sun
authors: Hong-Bin
authors: HB
authors: Liu
authors: Zhi-Feng
authors: ZF
authors: Wang
authors: Jin-da
authors: JD
authors: Wang
authors: Lu-Yue
authors: LY
authors: Gai
mesh_terms: D054058:Acute Coronary Syndrome / Q000473:pathology / Q000628:therapy; D000368:Aged; D000787:Angina Pectoris / Q000473:pathology* / Q000628:therapy; D015906:Angioplasty, Balloon, Coronary; D017023:Coronary Angiography / Q000379:methods; D003324:Coronary Artery Disease / Q000473:pathology* / Q000628:therapy; D054855:Drug-Eluting Stents / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D058226:Plaque, Atherosclerotic / Q000473:pathology; D011391:Prolapse; D012189:Retrospective Studies; D012307:Risk Factors; D041623:Tomography, Optical Coherence / Q000379:methods