title: Familial ossification of the stylohyoid ligament in a three generation family--a new clinical entity displaying autosomal dominant inheritance.
abstract: Ossification of the stylohyoid ligament is very common in the Caucasian population. More than 9000 descriptions of apparently isolated case reports on PubMed have been cited over the last 20 years, often associated with an incidental finding on imaging after neck trauma. No cases of familial ossification have been described. We document a family with several affected members, each with an ossified stylohyoid ligament, confirming that ossification may be hereditary in some families and is most likely due to an autosomal dominant gene.
authors: Regional Medical Genetics Centre, Belfast HSC Trust, Belfast, UK. patrick.morrison@belfasttrust.hscni.net
authors: P J
authors: PJ
authors: Morrison
authors: R J
authors: RJ
authors: Morrison
authors: C S
authors: CS
authors: McKinstry
mesh_terms: D000328:Adult; D005260:Female; D005799:Genes, Dominant; D006801:Humans; D008875:Middle Aged; D009999:Ossification, Heterotopic / Q000000981:diagnostic imaging / Q000235:genetics*; D010375:Pedigree; D011859:Radiography; D013701:Temporal Bone / Q000002:abnormalities / Q000000981:diagnostic imaging