title: Survival after accidental extrahepatic distribution of Y90 microspheres to the mesentery during a radioembolization procedure.
abstract: We present the acute management and outcome of a patient after an accidental mesenteric distribution of Y90 microspheres during radioembolization (RE). This report describes and highlights: (1) the incidence of a significant reflux during a RE session while injecting into a replaced right hepatic artery from the superior mesenteric artery, (2) the appearance of diffuse mesenteric Y90 distribution in bremsstrahlung-imaging, (3) the management protocol with the radiation protection agent amifostine, (4) the development of typical adverse effects in the expected time window, and (5) survival of the patient without long-term sequelae. This report should sensitize physicians to this particular problem and may help to avoid as well as manage similar radioembolization incidences.
authors: Department of Nuclear Medicine, University Hospital, Bonn, Germany.
authors: Amir
authors: A
authors: Sabet
authors: Hojjat
authors: H
authors: Ahmadzadehfar
authors: Nico
authors: N
authors: Schäfer
authors: Kai
authors: K
authors: Wilhelm
authors: Heinrich
authors: H
authors: Schüller
authors: Samer
authors: S
authors: Ezziddin
mesh_terms: D000368:Aged; D006528:Carcinoma, Hepatocellular / Q000628:therapy*; D004621:Embolization, Therapeutic / Q000009:adverse effects*; D005119:Extravasation of Diagnostic and Therapeutic Materials / Q000150:complications* / Q000175:diagnosis*; D005260:Female; D005471:Fluoroscopy; D006801:Humans; D008113:Liver Neoplasms / Q000628:therapy*; D008643:Mesentery / Q000528:radiation effects*; D008863:Microspheres; D019275:Radiopharmaceuticals; D013668:Technetium Tc 99m Aggregated Albumin; D015021:Yttrium Radioisotopes / Q000009:adverse effects*
chemical_list: D019275:Radiopharmaceuticals; D013668:Technetium Tc 99m Aggregated Albumin; D015021:Yttrium Radioisotopes