title: [Haemophagocytic lymphohistiocytosis syndrome: a possible cause of multi-organ failure in severe head trauma?].
abstract: We report the case of a 26-year-old patient who was victim of severe head trauma following a trafic road accident. Two days after trauma, she had fever, pancytopenia and multi-organ failure. The haemophagocytic lymphohistiocytosis syndrome was suspected. This diagnosis was confirmed by biologic findings (elevated serum levels of ferritin and triglycerid) and histological findings (examination of bone marrow smears showing histiocytes phagocytosing blood cells). The evolution was unfavorable despite of corticotherapy and symptomatic measures.
authors: Service de réanimation médicale, CHU Habib Bourguiba, route El-Ain-Km 1, 3029 Sfax, Tunisie. anischaari2004@yahoo.fr
authors: A
authors: A
authors: Chaari
authors: I
authors: I
authors: Jedidi
authors: H
authors: H
authors: Chelly
authors: M
authors: M
authors: Bahloul
authors: M
authors: M
authors: Bouaziz
mesh_terms: D000063:Accidents, Traffic; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D001853:Bone Marrow / Q000473:pathology; D006259:Craniocerebral Trauma / Q000150:complications* / Q000601:surgery; D017809:Fatal Outcome; D005260:Female; D005293:Ferritins / Q000097:blood; D006801:Humans; D007958:Leukocyte Count; D051359:Lymphohistiocytosis, Hemophagocytic / Q000150:complications* / Q000473:pathology; D009102:Multiple Organ Failure / Q000209:etiology*; D019635:Neurosurgical Procedures; D010198:Pancytopenia / Q000150:complications; D010976:Platelet Count; D014280:Triglycerides / Q000097:blood
chemical_list: D000305:Adrenal Cortex Hormones; D014280:Triglycerides; D005293:Ferritins