title: Primary Ewing's sarcoma/primitive neuroectodermal tumor of the vagina in a 54-year-old woman: a case report.
abstract: BACKGROUND
  Ewing's sarcoma (ES)/primitive neuroectodermal tumor (PNET) of the genital tract of women is uncommon. Presentation in vagina is exceedingly rare.
  
  
  METHODS
  A 54-year-old Chinese woman presented with complaints of vaginal bleeding with fragmented bits occasionally. Physical examination revealed two nodules about 4 cm × 3 cm in the vagina. The immunohistochemical stains revealed a rare presentation of a primitive neuroectodermal tumor. The patient was treated with whole-pelvis external beam radiation, vaginal cylinder intracavitary brachytherapy, intracavitary afterloading radiotherapy and bilateral groin area radiotherapy. She died of clinical recurrence after 18 months of treatment.
  
  
  CONCLUSIONS
  This is the oldest but virgin case, treated with radiation completely, of primitive neuroectodermal tumor located in the vagina reported in the literature.
authors: Department of Gynecology, The First Affiliated Hospital of China Medical University, Shenyang, 110001 Liaoning, People's Republic of China.
authors: Xiaoyan
authors: X
authors: Pang
authors: Pan
authors: P
authors: Chen
authors: Fang
authors: F
authors: Wen
authors: Yi
authors: Y
authors: Zhang
mesh_terms: D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008875:Middle Aged; D018241:Neuroectodermal Tumors, Primitive, Peripheral / Q000175:diagnosis* / Q000532:radiotherapy*; D014625:Vaginal Neoplasms / Q000175:diagnosis* / Q000532:radiotherapy*