title: Facile synthesis of monodisperse superparamagnetic Fe3O4 Core@hybrid@Au shell nanocomposite for bimodal imaging and photothermal therapy.
abstract: A simple seed-mediated growth route is developed to fabricate monodisperse, uniform superparamagnetic Fe(3)O(4) core/gold shell structured nanocomposites with tunable sizes and optical properties, in which gold seed formation and attachment onto the core surface via S-Au covalent bonding proceeds almost simultaneously in the one-pot synthesis. The as-prepared nanocomposite is demonstrated to have a great potential for magnetic resonance imaging (MRI)-guided, focused photothermal tumor therapy under near-IR laser radiation.
authors: Key Laboratory for Ultrafine Materials of Ministry of Education, School of Materials Science and Engineering, East China University of Science and Technology, Shanghai, China.
authors: Wenjie
authors: W
authors: Dong
authors: Yongsheng
authors: Y
authors: Li
authors: Dechao
authors: D
authors: Niu
authors: Zhi
authors: Z
authors: Ma
authors: Jinlou
authors: J
authors: Gu
authors: Yi
authors: Y
authors: Chen
authors: Wenru
authors: W
authors: Zhao
authors: Xiaohang
authors: X
authors: Liu
authors: Changsheng
authors: C
authors: Liu
authors: Jianlin
authors: J
authors: Shi
mesh_terms: D045744:Cell Line, Tumor; D006046:Gold / Q000737:chemistry*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D058185:Magnetite Nanoparticles / Q000737:chemistry*; D053761:Nanocomposites / Q000737:chemistry / Q000627:therapeutic use*; D036103:Nanotechnology / Q000379:methods*; D010316:Particle Size; D011878:Radiotherapy / Q000379:methods*
chemical_list: D058185:Magnetite Nanoparticles; D006046:Gold