title: Relation between serum magnesium level and migraine attacks.
abstract: OBJECTIVE
  The determination of serum magnesium levels in migraine.
  
  
  METHODS
  In a case control study performed between January 2007 and December 2007 at Tabriz University of Medical Sciences, Tabriz, Iran, 140 migraine patients were enrolled and their level of serum magnesium was determined and the results were compared with 140 healthy people who did not have any headache, kidney, or gastrointestinal disorders, and no consumption of magnesium complements.
  
  
  RESULTS
  Migraine patients (22 male, 118 female) with a mean age of 33.82+/-10.31 and 140 healthy people (26 male, 114 female) with a mean age of (34.19+/-9.95) were enrolled. Forty patients had aura and 100 patients did not have aura. The average serum magnesium level in the patient group (26.14+/-4.3) was significantly lower than the control (31.09+/-4.32) group (p=0.000). There was no significant difference between the mean level of serum magnesium in patients with migraine with aura and without aura, however, there was a significant linear relationship between the amount of serum magnesium and the frequency of headache.
  
  
  CONCLUSIONS
  Serum magnesium in migraine patients was significantly lower than the normal population and related to the frequency of migraine attacks, supporting the use of magnesium in prevention and treatment of migraine.
authors: Department of Neurology, Tabriz University of Medical Sciences, Tabriz, Iran.
authors: Mahnaz
authors: M
authors: Talebi
authors: Dariush
authors: D
authors: Savadi-Oskouei
authors: Mehdi
authors: M
authors: Farhoudi
authors: Solmaz
authors: S
authors: Mohammadzade
authors: Seyyedjamal
authors: S
authors: Ghaemmaghamihezaveh
authors: Akbar
authors: A
authors: Hasani
authors: Amir
authors: A
authors: Hamdi
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D015897:Comorbidity; D005260:Female; D006801:Humans; D007492:Iran / Q000453:epidemiology; D008274:Magnesium / Q000097:blood* / Q000502:physiology / Q000627:therapeutic use; D008275:Magnesium Deficiency / Q000097:blood / Q000175:diagnosis / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D008881:Migraine Disorders / Q000097:blood* / Q000175:diagnosis / Q000453:epidemiology*; D012720:Severity of Illness Index; D013997:Time Factors
chemical_list: D008274:Magnesium