title: Improved neurological function in a paediatric patient following Onyx embolization of a cervical glomus arteriovenous malformation.
abstract: Spinal cord intramedullary arteriovenous malformations (AVMs) pose a therapeutic challenge. Because of their complex angioanatomy, surgical excision of these lesions is difficult at best. Over the past decade, endovascular therapy has been established as an alternative treatment modality. As an embolic agent, N-butyl cyanoacrylate (NBCA) posed several problems such as difficulty of use and unpredictable performance. Onyx (ev3, Irvine, California, USA), an alternative liquid embolic agent, possesses several advantageous properties, such as increased control of agent delivery, over previous embolic agents like NBCA. However, reports of Onyx use in treating spinal intramedullary AVMs are still rare, especially in paediatric patients. We report a paediatric patient with glomus-type spinal intramedullary AVM treated successfully with Onyx with intermediate-term outcome.
authors: School of Medicine, Loma Linda University, USA.
authors: Gene
authors: G
authors: Kitamura
authors: J Paul
authors: JP
authors: Jacobson
authors: Alexander
authors: A
authors: Zouros
authors: Holly
authors: H
authors: Neglio
mesh_terms: D015901:Angiography, Digital Subtraction; D001165:Arteriovenous Malformations / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000628:therapy*; D002574:Cervical Vertebrae; D002675:Child, Preschool; D004121:Dimethyl Sulfoxide / Q000627:therapeutic use*; D004621:Embolization, Therapeutic / Q000379:methods*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D011145:Polyvinyls / Q000627:therapeutic use*; D013116:Spinal Cord / Q000098:blood supply* / Q000473:pathology; D014711:Vertebral Artery / Q000002:abnormalities / Q000000981:diagnostic imaging
chemical_list: C450660:Onyx copolymer; D011145:Polyvinyls; D004121:Dimethyl Sulfoxide