title: Physiological and electroencephalographic responses to acute exhaustive physical exercise in people with juvenile myoclonic epilepsy.
abstract: Although the available evidence suggests that exercise may positively affect epilepsy, whether this effect is applicable to different types of epilepsy has not been established. Physiological responses during rest, acute physical effort, and a recovery period were studied by concomitant analysis of cerebral electric activity using EEGs in subjects with juvenile myoclonic epilepsy (JME) and healthy controls. In addition, level of habitual physical activity, body composition, and 1 week of actigraphy monitoring data were evaluated. Twenty-four subjects (12 with JME and 12 controls) participated in this study. Compared with the control group, the JME group had a significantly lower V˙O(2) at rest (13.3%) and resting metabolic rate (15.6%). The number of epileptiform discharges in the JME group was significantly reduced during the recovery period (72%) compared with the resting state. There were no significant differences between the JME and control groups in behavioral outcomes and sleep parameters evaluated by actigraphy monitoring. The positive findings of our study strengthen the evidence for the benefits of physical exercise for people with JME.
authors: Departamento de Psicobiologia, Universidade Federal de São Paulo, São Paulo (SP), Brazil.
authors: Cristiano
authors: C
authors: de Lima
authors: Rodrigo Luiz
authors: RL
authors: Vancini
authors: Ricardo Mario
authors: RM
authors: Arida
authors: Laura M F F
authors: LM
authors: Guilhoto
authors: Marco Túlio
authors: MT
authors: de Mello
authors: Amaury Tavares
authors: AT
authors: Barreto
authors: Mirian Salvadori Bittar
authors: MS
authors: Guaranha
authors: Elza Márcia Targas
authors: EM
authors: Yacubian
authors: Sergio
authors: S
authors: Tufik
mesh_terms: D056044:Actigraphy; D000293:Adolescent; D000328:Adult; D000886:Anthropometry; D001823:Body Composition / Q000502:physiology; D058256:Brain Waves / Q000502:physiology*; D004569:Electroencephalography / Q000379:methods; D015444:Exercise / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009043:Motor Activity / Q000502:physiology*; D020190:Myoclonic Epilepsy, Juvenile / Q000473:pathology / Q000503:physiopathology*; D011795:Surveys and Questionnaires; D055815:Young Adult