title: False-positive human immunodeficiency virus antibody test and autoimmune hemolytic anemia in a patient with angioimmunoblastic T-cell lymphoma.
abstract: A 44-year-old woman was admitted with generalized lymphadenopathy, which was diagnosed as angioimmunoblastic T-cell lymphoma (AITL). The patient showed autoimmune hemolytic anemia (AIHA), polyclonal hypergammaglobulinemia and a high antinuclear antibody titer. Moreover, a human immunodeficiency virus (HIV)-1/2 screening test using the particle agglutination method was reactive. After chemotherapy for AITL, the AIHA was eliminated, and the false-positive HIV results were no longer detected. Autoimmunity associated with AITL is the likely cause of the cross-reaction with HIV and the AIHA. It is important to recognize that the cross-reaction with HIV can be a potential complication in AITL as well as AIHA.
authors: Department of Hematology, Nephrology and Rheumatology, Akita University Graduate School of Medicine, Japan.
authors: Seiji
authors: S
authors: Shida
authors: Naoto
authors: N
authors: Takahashi
authors: Naohito
authors: N
authors: Fujishima
authors: Yoshihiro
authors: Y
authors: Kameoka
authors: Miho
authors: M
authors: Nara
authors: Masumi
authors: M
authors: Fujishima
authors: Hirobumi
authors: H
authors: Saitoh
authors: Hiroyuki
authors: H
authors: Tagawa
authors: Makoto
authors: M
authors: Hirokawa
authors: Ryo
authors: R
authors: Ichinohasama
authors: Kenichi
authors: K
authors: Sawada
mesh_terms: D015492:AIDS Serodiagnosis; D000328:Adult; D000744:Anemia, Hemolytic, Autoimmune / Q000150:complications*; D005189:False Positive Reactions; D005260:Female; D006801:Humans; D007119:Immunoblastic Lymphadenopathy / Q000150:complications*; D016399:Lymphoma, T-Cell / Q000150:complications*