Interfacing living yeast cells with graphene oxide nanosheaths.
The first example of the encapsulation of living yeast cells with multilayers of GO nanosheets via LbL self-assembly is reported. The GO nanosheets with opposite charges are alternatively coated onto the individual yeast cells while preserving the viability of the yeast cells, thus affording a means of interfacing graphene with living yeast cells. This approach is expanded by integrating other organic polymers or inorganic nanoparticles to the cells by hybridizing the entries with GO nanosheets through LbL self-assembly. It is demonstrated that incorporated iron oxide nanoparticles can deliver magnetic properties to the biological systems, allowing the integration of new physical and chemical functions for living cells with a combination of GO nanosheets.
Molecular-Level Interface Research Center, Department of Chemistry, Korea Advanced Institute of Science and Technology, Daejeon, Korea.
Sung Ho
SH
Yang
Taemin
T
Lee
Eunyong
E
Seo
Eun Hyea
EH
Ko
Insung S
IS
Choi
Byeong-Su
BS
Kim
D002470:Cell Survival; D020099:Coated Materials, Biocompatible / Q000737:chemistry*; D005022:Ethyldimethylaminopropyl Carbodiimide / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry; D006108:Graphite / Q000737:chemistry*; D058185:Magnetite Nanoparticles / Q000737:chemistry; D008422:Materials Testing / Q000379:methods*; D008855:Microscopy, Electron, Scanning; D053758:Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D010087:Oxides / Q000737:chemistry*; D055672:Static Electricity; D015003:Yeasts / Q000187:drug effects / Q000378:metabolism*
D020099:Coated Materials, Biocompatible; D058185:Magnetite Nanoparticles; D010087:Oxides; C041829:1-ethyl-3-(3-(dimethylamino)propyl)carbodiimide methiodide; D006108:Graphite; D005022:Ethyldimethylaminopropyl Carbodiimide