Repetitive magnetic stimulation of the phrenic nerves for diaphragm conditioning: a normative study of feasibility and optimal settings.
Electrical stimulation can enhance muscle function. We applied repetitive cervical magnetic phrenic stimulation (rCMS) to induce diaphragm contractions in 7 healthy subjects (800 ms trains; transdiaphragmatic pressure (Pdi) measurements; tolerance ratings). Each rCMS train produced a sustained diaphragm contraction. Sixty-five percent of the maximal available output at 15 Hz proved the best compromise between Pdi and discomfort with nonfatiguing contractions. rCMS appears feasible and should be investigated for diaphragm conditioning in appropriate clinical populations.
Service de Pneumologie et Réanimation et Centre de Neurostimulation Respiratoire, Groupe Hospitalier Pitié-Salpêtrière, Paris, France.
Dan
D
Adler
Stewart B
SB
Gottfried
Nathalie
N
Bautin
Tomislav
T
Mirkovic
Matthieu
M
Schmidt
Mathieu
M
Raux
Dragan
D
Pavlovic
Thomas
T
Similowski
Alexandre
A
Demoule
D015746:Abdominal Pain / Q000517:prevention & control; D000328:Adult; D003964:Diaphragm / Q000294:innervation* / Q000502:physiology / Q000503:physiopathology; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D007700:Kinetics; D055909:Magnetic Field Therapy / Q000009:adverse effects / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009119:Muscle Contraction; D018763:Muscle Fatigue; D009133:Muscular Atrophy / Q000517:prevention & control; D009334:Neck Muscles / Q000294:innervation*; D010791:Phrenic Nerve / Q000502:physiology*; D010865:Pilot Projects; D011312:Pressure; D012121:Respiration, Artificial / Q000009:adverse effects