Outcome of living kidney donors left with multiple renal arteries.
Individuals with kidneys having ≥ 2 arteries appear to have an increased incidence of hypertension. Whether kidney donors in whom the remaining kidney has ≥ 2 arteries are at increased risk of hypertension is unknown. Therefore, we studied 3685 kidney donors to determine whether donors left with a kidney having ≥ 2 arteries were at increased risk of hypertension, impaired renal function, or death. Cohorts were assigned based on our practice pattern and the anatomy of the donated kidney. Of the 3685 donors, 1211 were estimated to have a remaining kidney with ≥ 2 arteries. Mean follow-up time for the single-artery group was 14.1 (± 11.0) yr and 15.3 (± 11.2) yr for the ≥ 2 artery group. Six-month hospital readmission rate was 1.4% and 1.2%, hypertension was noted in 22.4% and 21.8% and proteinuria in 9.7% and 9.6%, and estimated glomerular filtration rate at last follow-up was 62 (± 28) and 62 (± 16) for single vs. ≥ 2 renal artery groups, respectively. Our data suggest no adverse clinical sequelae nor any decrease in long-term survival for donors left with a kidney having ≥ 2 renal arteries.
Department of Surgery, Division of Transplantation, University of Minnesota, Minneapolis, MN 55414, USA.
Michael D
MD
Rizzari
Thomas M
TM
Suszynski
Kristen J
KJ
Gillingham
Arthur J
AJ
Matas
Hassan N
HN
Ibrahim
D000328:Adult; D003404:Creatinine / Q000097:blood; D005260:Female; D005500:Follow-Up Studies; D005919:Glomerular Filtration Rate; D006801:Humans; D006973:Hypertension / Q000209:etiology; D007668:Kidney / Q000098:blood supply / Q000503:physiopathology*; D007677:Kidney Function Tests; D019520:Living Donors; D008297:Male; D009392:Nephrectomy / Q000009:adverse effects* / Q000401:mortality*; D011183:Postoperative Complications; D011379:Prognosis; D011507:Proteinuria / Q000209:etiology; D012077:Renal Artery / Q000002:abnormalities / Q000502:physiology*; D051437:Renal Insufficiency / Q000209:etiology; D015996:Survival Rate
D003404:Creatinine