[Chemotherapy in urologic oncology].
Chemotherapy is an effective treatment in urologic cancers either for localized tumor or metastatic disease. In urologic cancers, chemotherapy always takes part in a multidisciplinary strategy including surgery, oncology and radiotherapy. Except for metastatic testicular germ cell cancers, chemotherapy is a palliative treatment in other metastatic urologic cancers such as bladder and castration-resistant prostate carcinomas. In metastatic clear cell renal carcinomas, it has not any indication and anti-angiogenic drugs are the only therapeutic options. Neoadjuvant chemotherapy in non-metastatic muscle-invasive bladder cancers must be considered as a standard treatment in fit patients.
Service d'oncologie médicale, CHU Timone, France. jean-laurent.deville@sfr.fr
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Deville
D000230:Adenocarcinoma / Q000188:drug therapy; D000970:Antineoplastic Agents / Q000627:therapeutic use; D002295:Carcinoma, Transitional Cell / Q000188:drug therapy; D006801:Humans; D008297:Male; D009373:Neoplasms, Germ Cell and Embryonal / Q000188:drug therapy; D011471:Prostatic Neoplasms / Q000188:drug therapy; D013736:Testicular Neoplasms / Q000188:drug therapy; D001749:Urinary Bladder Neoplasms / Q000188:drug therapy; D014571:Urologic Neoplasms / Q000188:drug therapy*
D000970:Antineoplastic Agents