Plasma cell meningitis: a rare neurological complication of multiple myeloma requiring a high index of suspicion.
OBJECTIVE
Plasma cell meningitis is an uncommon neurologic complication of multiple myeloma with a very poor prognosis (median overall survival of 3 months).


METHODS
We describe a previously heavy treated 54-year-old caucasian female with Bence Jones multiple myeloma who developed, shortly after a good partial response to a third line therapy, a plasma cell meningitis. Intrathecal chemotherapy was give with achievement of a complete response and improvement of her neurologic status, being alive after more than 6 months of follow-up.


CONCLUSIONS
A high index of suspicion is necessary to diagnose this rae entity since treatment initiation may provide symptomatic relief and improve the quality of life.
Serviço de Hematologia, Hospital Santo António dos Capuchos, Lisboa, Portugal. ronolosi@gmail.com
R
R
Lopes da Silva
Isabel
I
Costa
Marta
M
Prata
Aida Botelho
AB
Sousa
D005260:Female; D006801:Humans; D008581:Meningitis / Q000473:pathology*; D008875:Middle Aged; D009101:Multiple Myeloma / Q000150:complications*; D010950:Plasma Cells / Q000473:pathology*