Recurrent localized primary cutaneous marginal-zone B cell lymphoma.
A 36-year-old man with a prior diagnosis of primary cutaneous marginal-zone B cell lymphoma presented with newly-developed, small, erythematous papules and nodules on his upper left arm and pink-to-skin-colored, clustered papules on his left forearm. A biopsy specimen and immunohistochemical analysis of the left arm lesions showed a lymphocytic infiltrate which stained positively for CD20 and Bcl-2 and negatively for CD10. A PET-CT scan was negative for any extra-cutaneous manifestations of disease. These clinicopathologic findings are indicative of recurrent localized primary cutaneous marginal-zone B cell lymphoma.
Department of Dermatology, New York University, New York, New York, USA.
Shoshana
S
Marmon
Julie
J
Chu
Rishi
R
Patel
Shane
S
Meehan
Miriam Keltz
MK
Pomeranz
D000328:Adult; D018951:Antigens, CD20 / Q000032:analysis; D001132:Arm; D000077610:Bexarotene; D014408:Biomarkers, Tumor / Q000032:analysis; D001706:Biopsy; D003131:Combined Modality Therapy; D006801:Humans; D019394:Ki-67 Antigen / Q000032:analysis; D018442:Lymphoma, B-Cell, Marginal Zone / Q000737:chemistry / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000737:chemistry / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy; D019253:Proto-Oncogene Proteins c-bcl-2 / Q000032:analysis; D012878:Skin Neoplasms / Q000737:chemistry / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy; D013764:Tetrahydronaphthalenes / Q000627:therapeutic use
D018951:Antigens, CD20; D014408:Biomarkers, Tumor; D019394:Ki-67 Antigen; D019253:Proto-Oncogene Proteins c-bcl-2; D013764:Tetrahydronaphthalenes; D000077610:Bexarotene