Angiographically silent cystoid macular oedema secondary to paclitaxel therapy.
Bilateral macular oedema is an uncommon side-effect of paclitaxel administration in oncological patients. We report the case of a 64-year-old man who presented with decreased visual acuity due to bilateral macular oedema after paclitaxel administration for lung cancer. Optical coherence tomography scans of both eyes revealed cystoid macular oedema. Fluorescein angiography demonstrated the unusual finding of the absence of localised retinal capillary leakage. Ketorolac eye drops and acetazolamide tablets were prescribed and one month later the cystoid macular oedema resolved with subsequent improvement in visual acuity. This case illustrates the unusual presentation of cystoid macular oedema induced by paclitaxel.
Department of Ophthalmology, University of Patras, Medical School, Patras, Greece. cgeorg@upatras.gr
Constantine D
CD
Georgakopoulos
Olga E
OE
Makri
Panagiotis
P
Vasilakis
Artemis
A
Exarchou
D000972:Antineoplastic Agents, Phytogenic / Q000009:adverse effects; D002289:Carcinoma, Non-Small-Cell Lung / Q000188:drug therapy*; D005451:Fluorescein Angiography; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy*; D008269:Macular Edema / Q000139:chemically induced* / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D017239:Paclitaxel / Q000009:adverse effects*; D041623:Tomography, Optical Coherence
D000972:Antineoplastic Agents, Phytogenic; D017239:Paclitaxel