[Risk factors and psychosocial disability of treatment-resistant depression].
Resistant and/or chronic depression has severe consequences on social and professional functioning. Clinical and health-economic studies allowed the identification of the main factors involved in these adverse outcomes. Some factors are illness-dependent or related to personal characteristics, while others are linked to a wide range of psychosocial stresses. Guidelines have been developed to improve the pharmacological treatment of resistant depression, but they are not easy to implement and therapeutic failures are frequent. The knowledge of the factors influencing the evolution of depressive syndromes gives an empirical basis to assess their consequences on work capacity. It should also guide public health policies.
Service de psychiatrie générale, Département de santé mentale et de psychiatrie, HUG - Belle-Idée Chemin du Petit-Bel-Air 2, 1225 Chêne-Bourg. patrick.baud@hcuge.ch
Patrick
P
Baud
D000928:Antidepressive Agents / Q000627:therapeutic use; D002908:Chronic Disease; D003863:Depression / Q000188:drug therapy* / Q000209:etiology / Q000517:prevention & control* / Q000628:therapy; D006801:Humans; D011613:Psychotherapy; D018570:Risk Assessment; D012307:Risk Factors; D055502:Secondary Prevention; D012944:Social Support; D013315:Stress, Psychological / Q000150:complications; D014937:Work; D014938:Work Capacity Evaluation
D000928:Antidepressive Agents