A database for animal tuberculosis (mycoDB.es) within the context of the Spanish national programme for eradication of bovine tuberculosis.
Spoligotyping and mycobacterial interspersed repetitive unit-variable number tandem repeat (MIRU-VNTR) analysis are the international standard techniques for molecular typing of members of the Mycobacterium tuberculosis complex. To enable the exploitation of molecular typing data for epidemiological purposes, the creation of large databases is indispensable. Here we describe mycoDB.es, a database for animal tuberculosis which forms part of the Spanish national programme for eradication of bovine tuberculosis. This database has been created as an epidemiological tool at national level and contains spoligotype patterns of 17,273 isolates clustered in 401 different spoligotypes of Mycobacterium bovis, Mycobacterium caprae and M. tuberculosis. The database offers an overview of the present spoligotypes, to a lower extent also of MIRU-VNTR types, affected animal species and furthermore of the spatial distribution of these genotypes.
Centro de Vigilancia Sanitaria Veterinaria (VISAVET), Universidad Complutense de Madrid, 28040 Madrid, Spain.
Sabrina
S
Rodriguez-Campos
Sergio
S
González
Lucía
L
de Juan
Beatriz
B
Romero
Javier
J
Bezos
Carmen
C
Casal
Julio
J
Álvarez
Isabel G
IG
Fernández-de-Mera
Elena
E
Castellanos
Ana
A
Mateos
José L
JL
Sáez-Llorente
Lucas
L
Domínguez
Alicia
A
Aranaz
D000818:Animals; D015373:Bacterial Typing Techniques; D002417:Cattle; D019295:Computational Biology / Q000379:methods; D004269:DNA, Bacterial; D030541:Databases, Genetic; D020407:Internet; D018598:Minisatellite Repeats; D058889:Molecular Typing; D009163:Mycobacterium bovis / Q000145:classification* / Q000235:genetics* / Q000302:isolation & purification; D009313:National Health Programs; D058974:Phylogeography; D057386:Search Engine; D013030:Spain; D014380:Tuberculosis, Bovine / Q000453:epidemiology* / Q000382:microbiology
D004269:DNA, Bacterial