[Pseudopapillary solid tumor of the pancreas: report of 6 cases].
OBJECTIVE
Solid pseudopapillary neoplasms (SPNs) are rare tumours of the exocrine pancreas. Although they can develop metastasis, the prognosis is good. The aim of this study was to describe the characteristics of these tumours attended in our hospital.


METHODS
All cases of SPN in the database of the Pathology Department between 1991 and 2010 were included. Age, sex, symptoms, type of surgery, pathologic and immunohistochemical characteristics, and clinical evolution were analyzed.


RESULTS
Six cases were identified; all of them were women with a median age of 27.5 years. One patient presented haemoperitoneum, 2 abdominal pain and 3 were diagnosed incidentally. The most frequent localization was the pancreatic tail (n=4) and the median size was 7.7 cm. Four tumours were benign and 2 carcinomas. One of them had liver and lymph node metastases. Ki-67 proliferation index was low (1-3%). After a median follow-up of 33.5 months, all patients were alive and without evidence of relapse.


CONCLUSIONS
SPNs occur in young women. In most cases surgical resection is curative. A low mitotic index confers a good prognosis and a long survival.
Servicio de Gastroenterología, Hospital Clínic, Universidad de Barcelona, IDIBAPS, CIBERehd, Barcelona, España. snavarro@clinic.ub.es
Salvador
S
Navarro
Joana
J
Ferrer
Josep Antoni
JA
Bombí
Miguel Angel
MA
López-Boado
Juan Ramón
JR
Ayuso
Angels
A
Ginés
Gloria
G
Fernández-Esparrach
Eva
E
Vaquero
Miriam
M
Cuatrecasas
Laureano
L
Fernández-Cruz
D000328:Adult; D002291:Carcinoma, Papillary / Q000175:diagnosis / Q000378:metabolism / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D019394:Ki-67 Antigen / Q000378:metabolism; D008875:Middle Aged; D010180:Pancreatectomy; D010190:Pancreatic Neoplasms / Q000175:diagnosis / Q000378:metabolism / Q000601:surgery; D012189:Retrospective Studies
D019394:Ki-67 Antigen