New directions for drug discovery in psychiatric disease.
Although many new potential drug targets have been discovered subsequent to the cloning of the human genome and the discovery of most of the relevant receptors, the role of these receptors in psychiatric disease is still not clear. We argue that research into the disease process leading to new animal models that can be transposed to man is critical to drug discovery, and present an example of an animal model for schizophrenia using electroencephalography.
Institut de Recherches Internationales Servier, Neuilly-sur-Seine, France.
Michael
M
Speeding
Claude
C
Sebban
Laurent
L
Perret