Lymphohistiocytoid mesothelioma of the pleura: a case report with cytological findings.
Lymphohistiocytoid malignant mesothelioma is an infrequent variant of sarcomatoid mesothelioma representing approximately 0.5-3.3% of malignant mesotheliomas. It has been related to asbestos exposure. The tumor is characterized by a diffuse large histiocyte-like cells proliferation mixed with an inflammatory infiltrate of lymphocytes and plasma cells. Its cytological diagnosis is difficult. We present a case of a 67-year-old female with lymphohistiocytoid mesothelioma involving the left pleura. The cytological, histological, and immunohistochemical features are discussed.
Laboratory of Cytology, Department of Obstetrics, Gynecology and Reproduction, USP-Institut Universitari Dexeus, Barcelona, Spain. fratre@dexeus.com
Francisco
F
Tresserra
Miriam
M
Castella
Gemma
G
Fabra
Maria
M
Angeles Martinez
Mariasun
M
Dominguez
Carmen
C
Fernandez-Cid
Maria Dolors
MD
Amalrich
Carolina
C
Ramos
D000368:Aged; D005260:Female; D006644:Histiocytes / Q000473:pathology; D006801:Humans; D008214:Lymphocytes / Q000473:pathology; D008654:Mesothelioma / Q000175:diagnosis* / Q000473:pathology; D010994:Pleura / Q000473:pathology*; D010997:Pleural Neoplasms / Q000175:diagnosis* / Q000473:pathology