Malaria prevalence and morbidity among children reporting at health facilities in Nouakchott, Mauritania.
Although malaria has become a serious public health problem in Mauritania since the late 1990s, few documented data on its epidemiology exist. The objective of this study was to assess the morbidity of clinical malaria among children in Nouakchott. Three hundred and one febrile children, consulting at three health facilities of Nouakchott, were screened for malaria in 2009 (n=216) and 2010 (n=85). Plasmodium species identification and parasite density were determined by microscopic examination of Giemsa-stained thin and thick films and confirmed by rapid diagnostic test and nested PCR. Of 301 febrile children, 105 (34.9%) were malaria-positive by nested PCR and 87 (28.9%) by microscopy. Plasmodium vivax represented 97.1% (102/105) and P. falciparum accounted for 2.9% (3/105) of positive cases. All positive children under five years old were infected with P. vivax. The highest numbers of malaria positives were found during or shortly after the rainy season and the lowest during the dry season. Fifty-four of 105 (51.4%) malaria cases, all with P. vivax, had never travelled outside Nouakchott. Individuals belonging to the Moors ethnic group represented 97.0% of P. vivax cases. Results of the present study indicate that malaria is endemic in Nouakchott and that P. vivax is the principal causative agent. Regular surveillance is required to monitor malaria prevalence and incidence, and further measures are needed to counter the possible spread of malaria in the country.
Laboratoire de Biotechnologies, Université de Nouakchott, Mauritania.
Khadijetou Mint
KM
Lekweiry
Leonardo K
LK
Basco
Mohamed Salem O Ahmedou
MS
Salem
Jamal Eddine
JE
Hafid
Adeline
A
Marin-Jauffre
Abdallahi O
AO
Weddih
Sébastien
S
Briolant
Hervé
H
Bogreau
Bruno
B
Pradines
Christophe
C
Rogier
Jean-François
JF
Trape
Ali O Mohamed Salem O
AO
Boukhary
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005260:Female; D005334:Fever / Q000469:parasitology; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008288:Malaria / Q000453:epidemiology* / Q000235:genetics / Q000635:transmission; D008297:Male; D008435:Mauritania / Q000453:epidemiology; D010963:Plasmodium falciparum / Q000302:isolation & purification* / Q000472:pathogenicity*; D010966:Plasmodium vivax / Q000302:isolation & purification* / Q000472:pathogenicity*; D016133:Polymerase Chain Reaction; D015995:Prevalence; D012621:Seasons; D018571:Sentinel Surveillance