hCG, five independent molecules.
BACKGROUND
The hCG amino acid sequence supports 5 glycoproteins. All are called hCG forms. This review examines all 5 molecules, the hormone as produced by the placental syncytiotrophoblast cells, the sulfated hormone produced by the pituitary gonadotrope cells, the hyperglycosylated hCG autocrine made by placental cytotrophoblast cells, and the autocrine cancer promoters hyperglycosylated hCG, hCGß and hyperglycosylated hCGß as made by all malignancies. This review examines all the molecules and multiple proven functions, ranging from evolution to cancer promotion to hormone action.


CONCLUSIONS
hCG forms are critical super-growth factors in humans, with an exceptional wide range of functions.
USA hCG Reference Service Reference Service, Division of Women's Health Research, Albuquerque, NM 87104, United States. larry@hcglab.com
Laurence A
LA
Cole
D002240:Carbohydrate Sequence; D006063:Chorionic Gonadotropin / Q000737:chemistry*; D005260:Female; D006031:Glycosylation; D006801:Humans; D008958:Models, Molecular; D008969:Molecular Sequence Data; D011247:Pregnancy
D006063:Chorionic Gonadotropin