[Arguments for prophylactic therapy of ocular hypertension].
Increased intraocular pressure is currently the only manipulable risk factor for glaucoma. In ocular hypertension the intraocular pressure is increased but the optic nerve head and visual field are thought to show no damage. Classification into glaucoma by means of the optic nerve head is often possible only over a period of time because there is a large overlap between the already pathological and still normal findings. In the Ocular Hypertension Treatment Study (OHTS) the effectiveness of prophylactic treatment was demonstrated. In the OHTS and the European Glaucoma Prevention Study (EGPS) risk factors have been identified, such as increased intraocular pressure, size of the excavation of the optic nerve head, decreased central corneal thickness, increased pattern standard deviation in the visual field and age. Before treatment of ocular hypertension is initiated these risk factors and the patient's personal situation should be considered. The higher the intraocular pressure, the smaller the central corneal thickness and the larger the excavation of the optic nerve and the younger the patient, the earlier treatment should be started.
Augenklinik, Universitätsmedizin Mainz, Mainz, Deutschland. jochen.wahl@uni-mainz.de
J
J
Wahl
D000959:Antihypertensive Agents / Q000008:administration & dosage*; D019317:Evidence-Based Medicine; D005858:Germany; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects*; D009798:Ocular Hypertension / Q000188:drug therapy* / Q000517:prevention & control*; D016896:Treatment Outcome; D019564:Unnecessary Procedures
D000959:Antihypertensive Agents