Orphan cytokine reveals IL-17 family secret.
The biology of interleukin-17C (IL-17C) has remained largely a mystery for more than a decade. Chang et al. (2011), in this issue of Immunity, and two other reports (Song et al., 2011; Ramirez-Carrozzi et al., 2011) demonstrate that IL-17C has broad functions in a variety of tissues.
Merck Research Laboratories, 901 California Avenue, Palo Alto, CA 94304, USA.
Christopher J
CJ
Haines
Daniel J
DJ
Cua