Engineering aspects of biological ion channels--from biosensors to computational models for permeation.
This paper presents two important engineering aspects of biological ion channels-how to build sensors out of gramicidin channels and how to construct computational models for ion channel permeation. We describe our recent research in these areas, potential challenges and possible solutions.
Department of Electrical and Computer Engineering, University of British Columbia, Vancouver, V6T 1Z4, Canada. vikramk@ece.ubc.ca
Vikram
V
Krishnamurthy
Bruce
B
Cornell
D000818:Animals; D001692:Biological Transport; D015374:Biosensing Techniques / Q000379:methods*; D019295:Computational Biology / Q000379:methods*; D003198:Computer Simulation; D006096:Gramicidin / Q000378:metabolism; D006801:Humans; D007473:Ion Channels / Q000378:metabolism*; D008954:Models, Biological
D007473:Ion Channels; D006096:Gramicidin