Microwave-assisted synthesis of medium-sized heterocycles.
The development of new strategies for synthesis of medium-sized heterocycles has remained a highly attractive but challenging proposition. In the last few years, the application of microwave irradiation has greatly facilitated the construction of such heterocyclic ring systems through a myriad of different synthetic approaches. This feature article illustrates the progress made in the microwave-assisted synthesis of medium-sized heterocycles with an emphasis on examples describing the use of a dedicated microwave synthesizer.
Laboratory for Organic & Microwave-Assisted Chemistry (LOMAC), Department of Chemistry, Katholieke Universiteit Leuven, Celestijnenlaan 200F, B-3001, Leuven, Belgium.
Abhishek
A
Sharma
Prasad
P
Appukkuttan
Erik
E
Van der Eycken
D006571:Heterocyclic Compounds / Q000138:chemical synthesis*; D008872:Microwaves; D004364:Pharmaceutical Preparations / Q000138:chemical synthesis
D006571:Heterocyclic Compounds; D004364:Pharmaceutical Preparations