Erythrodermic lichen planus.
Lichen planus (LP) is a relatively common papulosquamous disorder that is characterized by pruritic, polygonal papules in a characteristic distribution. We present a case of a 71-year-old man with erythroderma, who was ultimately diagnosed with severe, generalized LP. Treatment of severe LP is challenging, and there are few, robust, clinical trials in the literature to guide the selection of appropriate treatment. We discuss the treatment options for generalized LP and the evidence in support of these agents.
Department of Dermatology, New York University, New York, New York, USA.
Amy E
AE
Rose
Utpal
U
Patel
Julie
J
Chu
Rishi
R
Patel
Shane
S
Meehan
Jo-Ann M
JA
Latkowski
D000368:Aged; D023341:Chills; D003873:Dermatitis, Exfoliative / Q000209:etiology*; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007155:Immunologic Factors / Q000627:therapeutic use; D017964:Itraconazole / Q000627:therapeutic use; D007871:Leg Ulcer / Q000209:etiology / Q000382:microbiology; D008010:Lichen Planus / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D008297:Male; D008795:Metronidazole / Q000627:therapeutic use; D011701:PUVA Therapy; D011537:Pruritus / Q000209:etiology; D016032:Randomized Controlled Trials as Topic; D012176:Retinoids / Q000627:therapeutic use; D013207:Staphylococcal Skin Infections / Q000150:complications; D013792:Thalidomide / Q000627:therapeutic use
D005938:Glucocorticoids; D007155:Immunologic Factors; D012176:Retinoids; D008795:Metronidazole; D017964:Itraconazole; D013792:Thalidomide