Association between metabolic syndrome and parameters of 24-hour blood pressure ambulatory monitoring.
OBJECTIVE
To investigate associations between metabolic syndrome (MS) and 24-hour blood pressure parameters as a measure of cardiovascular risk (CVR).


METHODS
136 hypertensive subjects, of both sexes, aged between 29 and 83 years were studied. CVR was defined as having at least three of the following conditions: 1) systolic/diastolic blood pressure (BP) ≥ 140/90 mmHg, absence/attenuation of nighttime fall in BP during sleep, pulse pressure (PP) ≥ 53 mmHg; 2) 24-h PP > 53 mmHg, 3) nighttime PP > 53 mmHg, 4) daytime PP > 53 mmHg and 5) nighttime fall in BP during sleep.


RESULTS
The 24-h PP, daytime PP and nighttime PP were elevated in 54% of the population. Hypertriglyceridemia (52%), low HDL (72.8%), abdominal obesity (60.3%), MS (58.1%), dyslipidemia (88.8%), overweight (74.3%) and obesity (33.8%) were also elevated. Age-adjusted MS was associated with higher CVR (OR = 4.5 and 3.6), 24-h PP (OR = 2.3 and 4.7), and daytime PP (OR = 2.2 and 4.6).


CONCLUSIONS
MS was highly prevalent and correlated with altered 24-hour blood pressure parameters.
Nursing School, Universidade Federal de Minas Gerais, Av. Alfredo Balena 190, Belo Horizonte, MG, Brazil.
Mariana Santos
MS
Felisbino-Mendes
Tatiane
T
Géa-Horta
Antônio Luiz Pinho
AL
Ribeiro
Gilberto
G
Kac
Salete Maria de Fátima
SM
Silqueira
Gustavo
G
Velásquez-Meléndez
D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D001794:Blood Pressure / Q000502:physiology*; D018660:Blood Pressure Monitoring, Ambulatory / Q000592:standards*; D002318:Cardiovascular Diseases / Q000453:epidemiology*; D002940:Circadian Rhythm / Q000502:physiology; D004812:Epidemiologic Methods; D005260:Female; D006801:Humans; D006973:Hypertension / Q000175:diagnosis* / Q000503:physiopathology; D008297:Male; D024821:Metabolic Syndrome / Q000453:epidemiology* / Q000503:physiopathology; D008875:Middle Aged; D011237:Predictive Value of Tests; D012307:Risk Factors