Just add tetrazole: 5-(2-pyrrolo)tetrazoles are simple, highly potent anion recognition elements.
We report a novel pyrrolo-tetrazole motif that encodes anion binding orders of magnitude stronger than closely related systems and suggests the general utility of amide-tetrazole exchanges for creating simple, high-affinity anion binders.
University of Victoria, Department of Chemistry, Victoria, V8W 3V6, Canada.
Rebecca J M
RJ
Courtemanche
Thomas
T
Pinter
Fraser
F
Hof
D000577:Amides / Q000737:chemistry; D000838:Anions / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D008968:Molecular Conformation; D013777:Tetrazoles / Q000737:chemistry*
D000577:Amides; D000838:Anions; D013777:Tetrazoles