Primary adenosquamous cell carcinoma of the pancreas: a case report with a review of the Korean literature.
The most common pancreatic cancer is adenocarcinoma. Primary adenosquamous cell carcinoma of the pancreas is very rare and aggressive. A 46-year-old man presented with a 3-month history of dyspepsia and a 7-kg weight loss. The physical examination showed tenderness of the right upper quadrant of the abdomen. There was no jaundice. Amylase and lipase were elevated. CA 19-9 was elevated to 566.7 U/mL. Gastroduodenoscopy showed a hard ulceroinfiltrative mass with a yellowish exudate that bled readily on touch in the second portion of the duodenum. Abdominal computed tomography showed a 7.1 × 6.3-cm heterogeneously enhancing mass in the pancreatic head. The pancreatic mass had invaded the duodenum wall, gastric antrum, and gastroduodenal artery sheath. Fine-needle aspiration biopsy of the pancreatic mass revealed adenosquamous cell carcinoma, anaplastic type. We concluded that an adenosquamous cell carcinoma of pancreas had invaded the duodenal mucosa causing ulceration.
Department of Internal Medicine, Ewha Womans University School of Medicine, Seoul, Korea.
Youn Ju
YJ
Na
Ki-Nam
KN
Shim
Min Sun
MS
Cho
Sun Hee
SH
Sung
Sung-Ae
SA
Jung
Kwon
K
Yoo
Kyu Won
KW
Chung
D000681:Amylases / Q000097:blood; D044963:Biopsy, Fine-Needle; D018395:CA-19-9 Antigen / Q000097:blood; D018196:Carcinoma, Adenosquamous / Q000097:blood / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D004384:Duodenoscopy; D004386:Duodenum / Q000473:pathology; D006801:Humans; D007413:Intestinal Mucosa / Q000473:pathology; D008049:Lipase / Q000097:blood; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D010190:Pancreatic Neoplasms / Q000097:blood / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D014057:Tomography, X-Ray Computed
D018395:CA-19-9 Antigen; D008049:Lipase; C518354:PNLIP protein, human; D000681:Amylases