Targeting RSK2 in myeloid leukemia: right for FLT3 but wrong for BCR-ABL.
Benjamin H
BH
Lee
Sumin
S
Kang
D000818:Animals; D002471:Cell Transformation, Neoplastic; D016044:Fusion Proteins, bcr-abl / Q000378:metabolism*; D007951:Leukemia, Myeloid / Q000235:genetics* / Q000378:metabolism / Q000628:therapy; D051379:Mice; D008954:Models, Biological; D038744:Ribosomal Protein S6 Kinases, 90-kDa / Q000378:metabolism / Q000502:physiology*; D015398:Signal Transduction; D051941:fms-Like Tyrosine Kinase 3 / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*
C497970:FLT3 protein, human; D051941:fms-Like Tyrosine Kinase 3; D016044:Fusion Proteins, bcr-abl; D038744:Ribosomal Protein S6 Kinases, 90-kDa; C069330:ribosomal protein S6 kinase, 90kDa, polypeptide 3