[Dipodascus capitatus (Geotrichum capitatum): fatal systemic infection on patient with acute myeloid leukemia].
The infections caused by Dipodascus capitatus are rare, and the treatment is difficult. We reported a case of a patient with acute myeloid leukemia. The fungus was first isolated from hemocultures, and the phenotypic identification was based on mycological methods. The genotyping was carried out by sequencing the region D1/D2 from 26 rDNA. The susceptibility tests were assayed by Etest® and by the microdilution technique. None of the antifungal treatments employed were effective. The patient died on day 17 after the mycological diagnosis. The authors discussed the emergence of such infections as well as the difficulty regarding the diagnosis and treatment.
Hospital Universitário de Santa Maria, Santa Maria, Brazil.
Thereza Christina Sampaio
TC
Lafayette
Loiva Therezinha Otonelli
LT
Oliveira
Melissa
M
Landell
Patrícia
P
Valente
Sydney Hartz
SH
Alves
Waldir Veiga
WV
Pereira
D000293:Adolescent; D004271:DNA, Fungal / Q000032:analysis; D004275:DNA, Ribosomal / Q000032:analysis; D055157:Dipodascus / Q000235:genetics / Q000302:isolation & purification*; D017809:Fatal Outcome; D005260:Female; D005838:Genotype; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000382:microbiology*; D008826:Microbial Sensitivity Tests; D009181:Mycoses / Q000382:microbiology*
D004271:DNA, Fungal; D004275:DNA, Ribosomal