Two new xanthones from Calophyllum nodusum (Guttiferae).
The air-dried powdered stem bark of Calophyllum nodusum (Guttiferea) collected from Sandakan (Sabah, Malaysia), was extracted sequentially with hexane, chloroform and methanol. The solvents were removed by rotary evaporator to give dark viscous extracts. Detailed and repeated chromatographic separation of the extracts lead to isolation of two new xanthones, identified as nodusuxanthone and trapezifolixanthone A. Other common terpenoids such as betulinic acid, lupeol, stigmasterol and friedelin were also isolated from the extracts and identified. The structures of the compounds were established by detailed spectral analysis and comparison with previously reported data.
Department of Chemistry, Universiti Putra Malaysia, 43400 UPM, Serdang, Malaysia.
Nadiah Mad
NM
Nasir
Mawardi
M
Rahmani
Khozirah
K
Shaari
Gwendoline Cheng Lian
GC
Ee
Rusea
R
Go
Nur Kartinee
NK
Kassim
Siti Noor Kamilah
SN
Muhamad
Mohd Johadi
MJ
Iskandar
D029759:Calophyllum / Q000033:anatomy & histology / Q000737:chemistry*; D006801:Humans; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D024301:Plant Bark / Q000737:chemistry*; D010936:Plant Extracts / Q000737:chemistry*; D044004:Xanthones / Q000737:chemistry* / Q000302:isolation & purification*
D010936:Plant Extracts; D044004:Xanthones