[Microbial profile and antibiotic susceptibility of chronic rhinosinusitis].
OBJECTIVE
To investigate distribution and drug-susceptibility of bacteria in patients with chronic rhinosinusitis.


METHODS
The purulent discharges or mucous membrane lesions were collected from the sinus of 51 patients with chronic rhinosinusitis receiving sinus surgery. The clinical specimens were incubated and the drug susceptibility was analyzed.


RESULTS
Of 51 specimens, 41 (80.39%) showed positive results in bacteria culture. The antibiotic susceptibility was as follows: vancomycin-100%, moxifloxacin-100%, levofloxacin-92.31%, rifampin-90.91%, ciprofloxacin-81.58%, SMZ-TMP-67.65%, azithromycin-47.62%, clarithromycin-45.00%, ampicillin sodium and sulbactam sodium-35.90%, cefatriaxone-39.39%, cefuroxime sodium-30.43%, penicillin-8.33%.


CONCLUSIONS
There are bacteria infections in most of chronic rhinosinusitis. The fluoroquinolones should be preferred in sinus surgery.
Department of Otolaryngology Head and Neck Surgery, the First Affiliated Hospital of Guangzhou Medical College, Guangzhou, 510120, China.
Lizhi
L
Xiao
Jing
J
Zheng
Lei
L
Yang
Jinhai
J
Chen
Yingshen
Y
Lu
Shan
S
Lu
Xiaowen
X
Zhang
D000293:Adolescent; D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects; D001424:Bacterial Infections / Q000382:microbiology*; D002908:Chronic Disease; D024881:Drug Resistance, Bacterial; D005260:Female; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D012852:Sinusitis / Q000382:microbiology*; D055815:Young Adult
D000900:Anti-Bacterial Agents