Cyclic bipyridine glycosides from the marine-derived actinomycete Actinoalloteichus cyanogriseus WH1-2216-6.
Cyanogrisides A-D (1-4), four new glycosidic derivatives of bipyridine featuring a novel cyclic glycoside generated by vicinal hydroxyl groups of an aglycone with both the anomeric center and the adjacent carbonyl of a keto sugar, were isolated from the marine-derived actinomycete Actinoalloteichus cyanogriseus WH1-2216-6. The structures of 1-4 were elucidated by spectroscopic analysis, X-ray single crystal diffraction, CD spectra, and chemical methods.
Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, PR China.
Peng
P
Fu
Peipei
P
Liu
Xia
X
Li
Yi
Y
Wang
Shuxia
S
Wang
Kui
K
Hong
Weiming
W
Zhu
D000192:Actinomycetales / Q000737:chemistry*; D018360:Crystallography, X-Ray; D003500:Cyclization; D006027:Glycosides / Q000138:chemical synthesis*; D008958:Models, Molecular; D015394:Molecular Structure; D011725:Pyridines / Q000737:chemistry*
D006027:Glycosides; D011725:Pyridines; C023666:pyridine