Biodegradation of ciprofloxacin in water and soil and its effects on the microbial communities.
While antibiotics are frequently found in the environment, their biodegradability and ecotoxicological effects are not well understood. Ciprofloxacin inhibits active and growing microorganisms and therefore can represent an important risk for the environment, especially for soil microbial ecology and microbial ecosystem services. We investigated the biodegradation of (14)C-ciprofloxacin in water and soil following OECD tests (301B, 307) to compare its fate in both systems. Ciprofloxacin is recalcitrant to biodegradation and transformation in the aqueous system. However, some mineralisation was observed in soil. The lower bioavailability of ciprofloxacin seems to reduce the compound's toxicity against microorganisms and allows its biodegradation. Moreover, ciprofloxacin strongly inhibits the microbial activities in both systems. Higher inhibition was observed in water than in soil and although its antimicrobial potency is reduced by sorption and aging in soil, ciprofloxacin remains biologically active over time. Therefore sorption does not completely eliminate the effects of this compound.
UFZ--Helmholtz Centre for Environmental Research, Department of Environmental Biotechnology, Leipzig, Germany. cristobal.girardi-lavin@ufz.de
Cristobal
C
Girardi
Josephine
J
Greve
Marc
M
Lamshöft
Ingo
I
Fetzer
Anja
A
Miltner
Andreas
A
Schäffer
Matthias
M
Kästner
D000900:Anti-Bacterial Agents / Q000378:metabolism*; D001673:Biodegradation, Environmental; D002939:Ciprofloxacin / Q000378:metabolism*; D012988:Soil Microbiology; D012989:Soil Pollutants / Q000378:metabolism*; D014871:Water Microbiology; D014874:Water Pollutants, Chemical / Q000378:metabolism*
D000900:Anti-Bacterial Agents; D012989:Soil Pollutants; D014874:Water Pollutants, Chemical; D002939:Ciprofloxacin