Are patients with the symptoms of overactive bladder and urodynamic detrusor overactivity different from those with overactive bladder but not detrusor overactivity?
BACKGROUND
The aim of this study is to identify the differences between patients with overactive bladder (OAB) and detrusor overactivity (DO) and those with OAB but without DO.


METHODS
We prospectively recruited patients with OAB symptoms between December 2008 and September 2009. All patients were required to complete a 3-day frequency-volume chart. Symptom severity was evaluated using the International Prostate Symptom Score (IPSS) and Overactive Bladder Symptom Score (OABSS) questionnaires. All patients also underwent urodynamic studies. Demographics, symptom severity, urinary frequency and volume, and urodynamic variables of patients with and without DO were compared.


RESULTS
Of the 133 enrolled patients (76 women and 57 men), DO was diagnosed in 80 patients (60.2%). All demographic variables were similar among the OAB patients, regardless of DO status. Total IPSS and OABSS scores did not differ between the OAB and DO groups. However, the nighttime urinary frequency subscore on the OABSS differed significantly between OAB patients with DO and without DO (p = 0.048). There were no significant differences in terms of urodynamic variables, urinary frequency, or urine volume between OAB patients with and without DO.


CONCLUSIONS
Patients with OAB symptoms and urodynamic DO show different clinical symptoms than OAB patients without DO. Patients with DO experience more frequent nocturnal urinary episodes.
Division of Urology, Department of Surgery, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.
Yu-Hua
YH
Fan
Chih-Chieh
CC
Lin
Alex T L
AT
Lin
Kuang-Kuo
KK
Chen
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011795:Surveys and Questionnaires; D053201:Urinary Bladder, Overactive / Q000503:physiopathology*; D014554:Urination; D014563:Urodynamics