Interpretation problems in a forensic case of abstinence determination using alcohol markers in hair.
In a child custody case a mother with a longstanding history of alcohol misuse had to show absolute abstinence for one year. She entered a residential rehabilitation for six months and was tested two months later by way of a hair test for ethyl glucuronide (EtG) with the result of 22 pg/mg in the proximal 0-1cm segment and the segments 1-2 cm and 2-3 cm being negative. This was interpreted as a minimum alcohol intake of 20-50 units per week in the month before sampling. Since the mother denied any alcohol intake a second hair sample was collected seven weeks after the first and analyzed for fatty acid ethyl esters (FAEEs) by a second laboratory. A low concentration of 0.03 ng/mg was measured within the 0-6 cm segment of recently bleached hair and was interpreted as showing no evidence of alcohol use during the last six months. Three further hair samples were analyzed during the next nine months with low EtG values (<2.4-3.3 pg/mg, 0-3 cm segment) and low FAEE values (0.27-0.53 ng/mg, 0-6 cm segment). These findings were summarized as indicating continued low alcohol consumption over the past one year period. As a consequence of the conflicting results, the case was dealt with in a hearing before the Family Division of the High Court of London. It was concluded in the judgment that the evidence did not indicate that the mother had consumed alcohol in the period tested by the hair samples. It was stated that the evidence in this case highlighted the need for the exercise of considerable caution when hair tests for alcohol are being interpreted and relied upon, both generally and particularly in isolation, and that this case is a proper reminder of the need for expert evidence to be given in a manner according to the Practice Direction.
University Hospital Charité, Institute of Legal Medicine, Turmstr. 21, Building N, 10559 Berlin, Germany. fritz.pragst@charite.de
Fritz
F
Pragst
D000437:Alcoholism / Q000534:rehabilitation*; D015415:Biomarkers / Q000032:analysis; D002648:Child; D002655:Child Custody / Q000331:legislation & jurisprudence; D002853:Chromatography, Liquid; D004952:Esters; D005227:Fatty Acids / Q000032:analysis*; D005260:Female; D005965:Glucuronates / Q000032:analysis*; D006197:Hair / Q000737:chemistry*; D006202:Hair Dyes; D006801:Humans; D008297:Male; D015813:Substance Abuse Detection / Q000379:methods*; D053719:Tandem Mass Spectrometry
D015415:Biomarkers; D004952:Esters; D005227:Fatty Acids; D005965:Glucuronates; D006202:Hair Dyes; C093924:ethyl glucuronide