Modifying Fe3O4-functionalized nanoparticles with N-halamine and their magnetic/antibacterial properties.
Magnetic/antibacterial bifunctional nanoparticles were fabricated through the immobilization of antibacterial N-halamine on silica-coated Fe(3)O(4)-decorated poly(styrene-co-acrylate acid) (PSA) nanoparticles. The samples were characterized by scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray photoelectron spectra (XPS), X-ray diffraction (XRD), energy-dispersive X-ray spectrometry (EDX), Fourier transform infrared (FTIR), and thermogravimetric analysis (TGA). The N-halamine was developed from the precursor 5,5-dimethylhydantoin (DMH) by chlorination treatment, and experimental results showed that the loading amount of DMH on the silica-coated Fe(3)O(4)-decorated poly(styrene-co-acrylate acid) nanoparticles was adjustable. The as-synthesized nanoparticles exhibited superparamagnetic behavior and had a saturation magnetization of 18.93 emu g(-1). Antibacterial tests showed that the resultant nanoparticles displayed enhanced antibacterial activity against both Gram-positive and Gram-negative bacteria compared with their bulk counterparts.
College of Chemistry, Jilin University and MacDiarmid Laboratory, Changchun 130021, People's Republic of China.
Alideertu
A
Dong
Shi
S
Lan
Jinfeng
J
Huang
Tao
T
Wang
Tianyi
T
Zhao
Linghan
L
Xiao
Weiwei
W
Wang
Xin
X
Zheng
Fengqi
F
Liu
Ge
G
Gao
Yuxin
Y
Chen
D000900:Anti-Bacterial Agents / Q000737:chemistry*; D001419:Bacteria / Q000187:drug effects; D006827:Hydantoins / Q000737:chemistry / Q000494:pharmacology; D058185:Magnetite Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D008855:Microscopy, Electron, Scanning; D046529:Microscopy, Electron, Transmission; D017550:Spectroscopy, Fourier Transform Infrared; D014961:X-Ray Diffraction
D000900:Anti-Bacterial Agents; D006827:Hydantoins; D058185:Magnetite Nanoparticles; C030615:5,5-dimethylhydantoin