A novel hemotropic Mycoplasma (hemoplasma) in a patient with hemolytic anemia and pyrexia.
A patient with chronic moderate neutropenia, acute hemolysis, and pyrexia was found to be infected with a novel hemoplasma species. A clinical response to doxycyline was noted, and moxifloxacin was added subsequently to aid infection clearance. This represents the first report of hemolysis in association with confirmed hemoplasma infection in a human.
Department of Microbiology, Derriford Hospital, Plymouth, United Kingdom.
Jane A
JA
Steer
Séverine
S
Tasker
Emily N
EN
Barker
Jørgen
J
Jensen
Joanne
J
Mitchell
Teresa
T
Stocki
Victoria J
VJ
Chalker
Mike
M
Hamon
D000743:Anemia, Hemolytic / Q000175:diagnosis* / Q000209:etiology; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D001372:Aza Compounds / Q000008:administration & dosage; D002908:Chronic Disease; D016000:Cluster Analysis; D004269:DNA, Bacterial / Q000737:chemistry / Q000235:genetics; D004275:DNA, Ribosomal / Q000737:chemistry / Q000235:genetics; D004318:Doxycycline / Q000008:administration & dosage; D005260:Female; D005334:Fever / Q000175:diagnosis* / Q000209:etiology; D024841:Fluoroquinolones; D006801:Humans; D008875:Middle Aged; D008969:Molecular Sequence Data; D000077266:Moxifloxacin; D009174:Mycoplasma / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification*; D009175:Mycoplasma Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology* / Q000473:pathology; D009503:Neutropenia / Q000175:diagnosis / Q000209:etiology; D010802:Phylogeny; D011804:Quinolines / Q000008:administration & dosage; D012336:RNA, Ribosomal, 16S / Q000235:genetics; D017422:Sequence Analysis, DNA
D000900:Anti-Bacterial Agents; D001372:Aza Compounds; D004269:DNA, Bacterial; D004275:DNA, Ribosomal; D024841:Fluoroquinolones; D011804:Quinolines; D012336:RNA, Ribosomal, 16S; D004318:Doxycycline; D000077266:Moxifloxacin