[Comparative analysis of volatile oils of Mahuang Fuzi Xixin decoction and its major constituted herbs by GC-MS].
OBJECTIVE
To evaluate the correlativity between volatile oils of Mahuang Fuzi Xixin decoction and its major constituted herbs in composition and proportion.


METHODS
The chemical compositions of volatile oils obtained by wet distillation from Mahuang Fuzi Xixin decoction and its major constituted herbs (Herba Ephedrae, processed Radix Aconiti Lateralis, Herba Asari) were analyzed by GC-MS.


RESULTS
44 volatile components of Mahuang Fuzi Xixin decoction were identified, which mainly derived from its constituted herbs Mahuang and Xixin. 68, 8, 39 volatile components were respectively identified from volatile oils of Herba Epherae, processd Radix Aconiti Lateralis and Herba Asari. There were apparent changes in composition and proportion between volatile oils of Mahuang Fuzi Xixin decoction and its major constituted herbs.


CONCLUSIONS
There are apparent changes not only in quantity but also in quality between decoction and its major constituted herbs. Meanwhile any changes in composition may lead to a change in efficacy.
School of Traditional Chinese Medicine, Southern Medical University/Guangdong Key Lab of Traditional Chinese Medicine, Guangzhou 510515, China. lsy1199@126.com
Shao-yu
SY
Liang
Xiao-mei
XM
Tan
Fei-long
FL
Chen
Jia-bo
JB
Luo
D031841:Aconitum / Q000737:chemistry*; D030023:Asarum / Q000737:chemistry*; D004365:Drugs, Chinese Herbal / Q000032:analysis / Q000737:chemistry*; D029790:Ephedra sinica / Q000737:chemistry*; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods; D009822:Oils, Volatile / Q000032:analysis* / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry
D004365:Drugs, Chinese Herbal; D009822:Oils, Volatile