Supramolecular stabilization of acid tolerant L-arabinose isomerase from Lactobacillus sakei.
L-Arabinose isomerase stability is a crucial criterion for the industrial application of this biocatalyst. Noria and NoriaPG are capable of increasing the L-arabinose isomerase stability not only at high temperatures but also at low pH. Such results highlight, for the first time, the use of the Noria series of molecules for protein stabilization and activation.
LMI CNRS UMR 5615, Université de Lyon 1, Villeurbanne, F69622, France.
Said
S
Jebors
Yannick
Y
Tauran
Nushin
N
Aghajari
Samira
S
Boudebbouze
Emmanuelle
E
Maguin
Richard
R
Haser
Anthony W
AW
Coleman
Moez
M
Rhimi
D019747:Aldose-Ketose Isomerases / Q000378:metabolism*; D006863:Hydrogen-Ion Concentration; D007778:Lactobacillus / Q000201:enzymology*; D008274:Magnesium / Q000737:chemistry; D008345:Manganese / Q000737:chemistry; D055550:Protein Stability; D013696:Temperature
D008345:Manganese; D019747:Aldose-Ketose Isomerases; C019715:L-arabinose isomerase; D008274:Magnesium