Expansion of MT neurons excitatory receptive fields during covert attentive tracking.
Primates can attentively track moving objects while keeping gaze stationary. The neural mechanisms underlying this ability are poorly understood. We investigated this issue by recording responses of neurons in area MT of two rhesus monkeys while they performed two different tasks. During the Attend-Fixation task, two moving random dot patterns (RDPs) translated across a screen at the same speed and in the same direction while the animals directed gaze to a fixation spot and detected a change in its luminance. During the Tracking task, the animals kept gaze on the fixation spot and attentively tracked the two RDPs to report a change in the local speed of one of the patterns' dots. In both conditions, neuronal responses progressively increased as the RDPs entered the neurons' receptive field (RF), peaked when they reached its center, and decreased as they translated away. This response profile was well described by a Gaussian function with its center of gravity indicating the RF center and its flanks the RF excitatory borders. During Tracking, responses were increased relative to Attend-Fixation, causing the Gaussian profiles to expand. Such increases were proportionally larger in the RF periphery than at its center, and were accompanied by a decrease in the trial-to-trial response variability (Fano factor) relative to Attend-Fixation. These changes resulted in an increase in the neurons' performance at detecting targets at longer distances from the RF center. Our results show that attentive tracking dynamically changes MT neurons' RF profiles, ultimately improving the neurons' ability to encode the tracked stimulus features.
Cognitive Neurophysiology Laboratory, Department of Physiology, McGill University, Montreal, Quebec H3G 1Y6, Canada.
Robert
R
Niebergall
Paul S
PS
Khayat
Stefan
S
Treue
Julio C
JC
Martinez-Trujillo
D000200:Action Potentials / Q000502:physiology; D000704:Analysis of Variance; D000818:Animals; D001288:Attention / Q000502:physiology*; D005163:Factor Analysis, Statistical; D005403:Fixation, Ocular / Q000502:physiology*; D008253:Macaca mulatta; D008297:Male; D009044:Motor Cortex / Q000166:cytology*; D009046:Motor Neurons / Q000145:classification / Q000502:physiology*; D017711:Nonlinear Dynamics; D010775:Photic Stimulation / Q000379:methods; D011930:Reaction Time / Q000502:physiology; D017603:Signal Detection, Psychological; D014794:Visual Fields / Q000502:physiology*