An unusual case of hepatic carcinosarcoma.
We report a rare case of a hepatic carcinosarcoma with rabdomyosarcomatous differentiation in its sarcomatous component. A 71-year old Caucasian female patient underwent a liver resection for a 4-cm lesion developed on an underlying HCV-related cirrhosis. Post-operative course was uneventful and the patient was discharged 5 days after surgery. At pathology, the tumor presented the features of hepatocellular carcinoma and rhabdomyosarcoma Three months later the patient experienced a liver recurrence, dying 2 months later for systemic disease. The reported case presents several peculiarities, i.e. the female gender, the HCV-related cirrhotic status, and the European origin of the patient. However, the outcome of our case confirms that this neoplasm pursues a highly aggressive course with poor prognosis.
Department of General Surgery and Organ Transplantation, Sapienza University of Rome, Italy.
Q
Q
Lai
G B
GB
Levi Sandri
F
F
Melandro
M
M
Di Laudo
M
M
Garofalo
N
N
Guglielmo
M
M
Grieco
U
U
Di Tondo
M
M
Rossi
P B
PB
Berloco
D000368:Aged; D002296:Carcinosarcoma / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D017809:Fatal Outcome; D005260:Female; D006498:Hepatectomy / Q000379:methods; D019698:Hepatitis C, Chronic / Q000150:complications; D006801:Humans; D033162:Incidental Findings; D007558:Italy; D008103:Liver Cirrhosis / Q000150:complications; D008113:Liver Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D009364:Neoplasm Recurrence, Local