Crassocolides N-P, three cembranoids from the Formosan soft coral Sarcophyton crassocaule.
Three new cembranoids crassocolides N-P (1-3), was isolated from the organic extract of a Formosan soft coral Sarcophyton crassocaule. These structures were elucidated on the basis of spectroscopic analyses and by comparison with those previously reported in literature. The cytotoxicity of these compounds toward various cancer cell lines has also been determined.
Department of Cosmetic Science, Chia-Nan University of Pharmacy and Science, Tainan 717, Taiwan.
Guey-Horng
GH
Wang
Ho-Cheng
HC
Huang
Jui-Hsin
JH
Su
Chiung-Yao
CY
Huang
Chi-Hsin
CH
Hsu
Yao-Haur
YH
Kuo
Jyh-Horng
JH
Sheu
D000818:Animals; D037421:Anthozoa / Q000737:chemistry*; D000970:Antineoplastic Agents / Q000737:chemistry* / Q000494:pharmacology; D002470:Cell Survival / Q000187:drug effects; D004224:Diterpenes / Q000737:chemistry*; D006367:HeLa Cells; D006801:Humans; D020128:Inhibitory Concentration 50; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D013624:Taiwan
D000970:Antineoplastic Agents; D004224:Diterpenes; C571313:crassocolide N; C571314:crassocolide O; C571315:crassocolide P