Rhomboid proteases in plants - still in square one?
Rhomboids are ubiquitous intramembrane serine proteases the sequences of which are found in nearly all sequenced genomes, including those of plants. They were molecularly characterized in a number of organisms, and were found to play a role in a variety of biological functions including signaling, development, apoptosis, mitochondrial integrity, parasite invasion and more. Although rhomboid sequences are found in plants, very little is known about their function. Here, we present the current knowledge in the rhomboids field in general, and in plant rhomboids in particular. In addition, we discuss possible physiological roles of different plant rhomboids.
The Robert H. Smith Institute of Plant Sciences and Genetics in Agriculture, The Hebrew University of Jerusalem, Rehovot 76100, Israel.
Ronit Rimon
RR
Knopf
Zach
Z
Adam
D017360:Arabidopsis / Q000201:enzymology* / Q000235:genetics / Q000502:physiology; D029681:Arabidopsis Proteins / Q000378:metabolism / Q000502:physiology; D020134:Catalytic Domain; D002462:Cell Membrane / Q000378:metabolism / Q000502:physiology; D004789:Enzyme Activation; D008565:Membrane Proteins / Q000378:metabolism* / Q000502:physiology; D008928:Mitochondria / Q000201:enzymology; D024101:Mitochondrial Proteins / Q000378:metabolism; D017434:Protein Structure, Tertiary; D059748:Proteolysis; D012697:Serine Endopeptidases / Q000378:metabolism / Q000502:physiology; D015398:Signal Transduction; D013379:Substrate Specificity
D029681:Arabidopsis Proteins; D008565:Membrane Proteins; D024101:Mitochondrial Proteins; C506071:RBL2 protein, Arabidopsis; D012697:Serine Endopeptidases