Prevalence of human leukocyte antigen HLA-B*57:01 in HIV-infected subjects in the Czech Republic.
The HLA-B*57:01 allele is associated with a hypersensitivity reaction to abacavir, and its prevalence varies in different populations. The aim of the study was to investigate HLA-B*57:01 prevalence in the Czech HIV-infected population. HLA-B*57:01 prevalence in our cohort was 5.33%, which is similar to the situation in other Central European countries.
Department of Infectious and Tropical Diseases, First Faculty of Medicine, Charles University in Prague, Czech Republic.
David
D
Jilich
Milena
M
Vraná
Svatava
S
Snopková
Dalibor
D
Sedlácek
Jaroslav
J
Kapla
Hanus
H
Rozsypal
Jitka
J
Kolcáková
Lenka
L
Olbrechtová
Alena
A
Zjevíková
Zdenka
Z
Jerhotová
Marek
M
Malý
Marie
M
Stanková
Ladislav
L
Machala
D019380:Anti-HIV Agents / Q000009:adverse effects; D003430:Cross-Sectional Studies; D018153:Czech Republic / Q000453:epidemiology; D015224:Dideoxynucleosides / Q000009:adverse effects; D004342:Drug Hypersensitivity / Q000175:diagnosis / Q000453:epidemiology*; D015658:HIV Infections / Q000097:blood / Q000188:drug therapy; D015235:HLA-B Antigens / Q000097:blood; D006801:Humans; D015995:Prevalence; D000099227:Abacavir
D019380:Anti-HIV Agents; D015224:Dideoxynucleosides; D015235:HLA-B Antigens; D000099227:Abacavir; C484830:HLA-B*57:01 antigen