Clinical experience with a novel bovine collagen dura mater substitute.
BACKGROUND
Dural substitutes are used to achieve a watertight closure in situations where adequate closure is not possible .This study was conducted to evaluate the efficacy and safety of use a new collagen matrix dural substitute ( Duradry, Tecnodry, Belo Horizonte MG) in repair or expansion of cranial and spinal dura-mater.


METHODS
30 patients operated on between March and September 2008, were studied. Surgical logs were reviewed for sex, age, diagnosis, location of the graft, technique and presence of fistula or infection. The patients were followed-up for at least 3 months, and the presence of complications as cerebrospinal leakage, infection, aseptic meningitis, hydrocephalus, pseudomeningocele were analysed.


RESULTS
Only one patient presented with CSF fistula. No patients presented with wound infections, hydrocephalus, pseudomeningocele, meningitis, brain abscesses or signs of toxicity related to the material.


CONCLUSIONS
The new dural substitute used in this study is effective and safe, and the initial results are similar to those of other dural substitutes reported in the literature.
Department of Neurosurgery, Hospital Santa Casa de Belo Horizonte, Minas Gerais, Brazil.
Bruno Silva
BS
Costa
George de Albuquerque
Gde A
Cavalcanti-Mendes
Marcelo Sartori
MS
de Abreu
Atos Alves
AA
de Sousa