A graphene oxide platform for the assay of biomolecules based on chemiluminescence resonance energy transfer.
The bifunctionality of graphene oxide (GO) that can highly adsorb single-stranded DNA (ssDNA) and effectively quench the emission of organic dyes is reasonably utilized in a chemiluminescence resonance energy transfer (CRET) system, achieving sensitive and selective detection of DNA (H1V1) and protein (thrombin), respectively.
State Key Laboratory Base of Eco-chemical Engineering, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, PR China. bisai11@126.com
Sai
S
Bi
Tingting
T
Zhao
Baoyu
B
Luo
D015374:Biosensing Techniques / Q000379:methods*; D004247:DNA / Q000032:analysis* / Q000737:chemistry; D004735:Energy Transfer; D019793:Fluorescein / Q000737:chemistry; D006108:Graphite / Q000737:chemistry*; D006735:Horseradish Peroxidase / Q000378:metabolism; D006861:Hydrogen Peroxide / Q000737:chemistry; D008163:Luminescent Measurements; D010087:Oxides / Q000737:chemistry*; D013917:Thrombin / Q000032:analysis* / Q000737:chemistry
D010087:Oxides; D006108:Graphite; D004247:DNA; D006861:Hydrogen Peroxide; D006735:Horseradish Peroxidase; D013917:Thrombin; D019793:Fluorescein