Risk factors for postpartum hypertension in women with twin pregnancies.
OBJECTIVE
Which physical findings and blood parameters predict postpartum hypertension remain to be studied in women with twin pregnancies.


METHODS
The antenatal systolic and diastolic blood pressures (SBP and DBP, respectively), and 16 laboratory variables were investigated in 150 normotensive women who gave birth to twins.


RESULTS
When the median values of the 18 continuous variables were used as cut-off values, an SBP>120 mm Hg (relative risk [95% confidence interval], 2.81 [1.94-4.08]), a DBP>70 mm Hg (2.42 [1.68-3.49]), an aspartate aminotransferase level>18 U/L (2.22 [1.55-3.19]), and a uric acid level>5.3 mg/dL (1.68 [1.20-2.36]) were independent risk factors for postpartum hypertension.


CONCLUSIONS
Antenatal blood pressure measurements and a laboratory work-up may be useful clinically for predicting postpartum hypertension in women with twin pregnancies.
Department of Obstetrics, Hokkaido University Graduate School of Medicine, Sapporo, Japan. mmamoru@med.hokudai.ac.jp
Mamoru
M
Morikawa
Kazutoshi
K
Cho
Takashi
T
Yamada
Takahiro
T
Yamada
Rina
R
Akaishi
Takahiro
T
Koyama
Masamitsu
M
Takeda
Ryutaro
R
Nishida
Hisanori
H
Minakami
D000328:Adult; D000410:Alanine Transaminase / Q000097:blood; D001219:Aspartate Aminotransferases / Q000097:blood; D001806:Blood Urea Nitrogen; D003404:Creatinine / Q000097:blood; D003971:Diastole; D005260:Female; D006801:Humans; D006973:Hypertension / Q000453:epidemiology*; D010976:Platelet Count; D011247:Pregnancy; D059285:Pregnancy, Twin; D011644:Puerperal Disorders / Q000453:epidemiology*; D012307:Risk Factors; D013599:Systole; D014527:Uric Acid / Q000097:blood
D014527:Uric Acid; D003404:Creatinine; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase