HLA-A*33:25, a novel allele identified by sequence-based typing, is a well-documented allele in Koreans.
The new allele, HLA-A*33:25, differs from A*33:03:01 by one nucleotide substitution in exon 4 (c.778G>A) which results in an amino acid change at codon 236 [GCA→ACA (Ala>Thr)] in β2-microglobulin-binding domain.
Department of Laboratory Medicine, Seoul Paik Hospital, Inje University College of Medicine, Seoul, Korea.
S Y
SY
Joo
E Y
EY
Song
J Y
JY
Huh
M S
MS
Kang
M H
MH
Park
D000328:Adult; D000483:Alleles; D019943:Amino Acid Substitution; D044466:Asian People; D001483:Base Sequence; D016026:Bone Marrow Transplantation; D036101:Cord Blood Stem Cell Transplantation; D005091:Exons; D005260:Female; D005787:Gene Frequency; D015234:HLA-A Antigens / Q000235:genetics* / Q000276:immunology; D006239:Haplotypes; D006650:Histocompatibility Testing; D006801:Humans; D008875:Middle Aged; D008969:Molecular Sequence Data; D017354:Point Mutation; D016133:Polymerase Chain Reaction; D017434:Protein Structure, Tertiary; D012042:Registries; D056910:Republic of Korea; D017422:Sequence Analysis, DNA
D015234:HLA-A Antigens; C082945:HLA-A*33 antigen