Streptobactin, a tricatechol-type siderophore from marine-derived Streptomyces sp. YM5-799.
A new catechol-type siderophore, streptobactin (1), was isolated from a culture broth of the marine-derived actinomycete Streptomyces sp. YM5-799. The structure of streptobactin was determined by NMR and MS analyses and ESIMS/MS experiments to be a cyclic trimer of benarthin. A dibenarthin (2), a tribenarthin (3), and benarthin (4) were also obtained. The production of 1 was regulated by an iron concentration in the culture. The iron-chelating activity of the compounds was evaluated by the chrome azurol sulfonate assay.
Suntory Holdings Ltd. , Yamazaki, Shimamoto, Mishima, Osaka 618-0001, Japan.
Yoshihide
Y
Matsuo
Kaneo
K
Kanoh
Jae-Hyuk
JH
Jang
Kyoko
K
Adachi
Satoru
S
Matsuda
Osamu
O
Miki
Toshiaki
T
Kato
Yoshikazu
Y
Shizuri
D004151:Dipeptides / Q000737:chemistry / Q000302:isolation & purification; D008386:Marine Biology; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010456:Peptides, Cyclic / Q000737:chemistry / Q000302:isolation & purification*; D017262:Siderophores / Q000737:chemistry / Q000302:isolation & purification*; D013302:Streptomyces / Q000737:chemistry
D004151:Dipeptides; D010456:Peptides, Cyclic; D017262:Siderophores; C569545:streptobactin; C076470:benarthin