Successful non-invasive treatment of stricturing fibrosing colonopathy in an adult patient.
OBJECTIVE
Fibrosing colonopathy (FC) is a rare entity associated with cystic fibrosis (CF). Until now, patients with stricturing FC have usually been treated surgically. In this instance, we aimed at avoiding surgery by applying a new conservative approach. -


METHODS
Case report on an adult with CF who developed persistent abdominal pain due to a non-passable stricture in the right transverse colon. Histology confirmed fibrosing colonopathy. -


RESULTS
Initially we treated the patient with prednisolone pulse therapy and additive antibiotic therapy. For maintenance therapy we administered budesonide. The patient underwent clinical, laboratory and endoscopic follow-up over a three-year period. The stricture healed and was easy to pass. A relapse in the cecum at the ileocecal valve again improved under steroid and antibiotic therapy. -


CONCLUSIONS
We present a novel therapeutic approach for advanced stricturing FC in an adult patient which successfully avoided surgery (right hemicolectomy) over a three year follow up.
Department of Medicine, Evangelisches Krankenhaus Duesseldorf, Duesseldorf, Germany. grischa.terheggen@evk-duesseldorf.de
G
G
Terheggen
D
D
Dieninghoff
E
E
Rietschel
U
U
Drebber
W
W
Kruis
L
L
Leifeld
D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D003106:Colon / Q000473:pathology*; D003108:Colonic Diseases / Q000188:drug therapy* / Q000209:etiology*; D003550:Cystic Fibrosis / Q000150:complications*; D005355:Fibrosis / Q000188:drug therapy* / Q000209:etiology*; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D013997:Time Factors; D016896:Treatment Outcome
D000900:Anti-Bacterial Agents