The value of growth hormone supplements in ART for poor ovarian responders.
Recently, three meta-analyses have concluded that cotreatment with GH improves assisted reproduction outcome in poor controlled ovarian stimulation responders. Although generally GH supplements did not increase controlled ovarian stimulation response or number of oocytes, the supplements improved pregnancy and live-birth rates-thus speaking for an effect on oocyte quality.
Université Paris Descartes-Assistance Publique Hôpitaux de Paris, CHU Cochin, Department of Obstetrics, Gynecology, and Reproductive Medicine, Paris, France. ddeziegler@orange.fr
Dominique
D
de Ziegler
Isabelle
I
Streuli
David R
DR
Meldrum
Charles
C
Chapron
D004359:Drug Therapy, Combination; D019317:Evidence-Based Medicine; D005260:Female; D005300:Fertility Agents, Female / Q000627:therapeutic use*; D013006:Growth Hormone / Q000627:therapeutic use*; D006801:Humans; D007246:Infertility / Q000503:physiopathology / Q000628:therapy*; D050498:Live Birth; D010053:Ovary / Q000187:drug effects* / Q000503:physiopathology; D010060:Ovulation / Q000187:drug effects*; D010062:Ovulation Induction / Q000379:methods*; D018579:Patient Selection; D011247:Pregnancy; D018873:Pregnancy Rate; D017211:Treatment Failure
D005300:Fertility Agents, Female; D013006:Growth Hormone