Curaxins: a new family of non-genotoxic multitargeted anticancer agents.
Dipartimento di Scienze Farmaceutiche, Università di Pisa, Via Bonanno 6-56126 Pisa, Italy.
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D000818:Animals; D000970:Antineoplastic Agents / Q000737:chemistry* / Q000494:pharmacology / Q000627:therapeutic use; D002227:Carbazoles / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use; D045744:Cell Line, Tumor; D049109:Cell Proliferation / Q000187:drug effects; D004247:DNA / Q000378:metabolism; D004268:DNA-Binding Proteins / Q000737:chemistry / Q000378:metabolism; D006609:High Mobility Group Proteins / Q000737:chemistry / Q000378:metabolism; D006801:Humans; D051379:Mice; D008862:Microsomes, Liver / Q000378:metabolism; D016328:NF-kappa B / Q000037:antagonists & inhibitors / Q000378:metabolism; D009369:Neoplasms / Q000188:drug therapy; D035602:Transcriptional Elongation Factors / Q000737:chemistry / Q000378:metabolism; D016159:Tumor Suppressor Protein p53 / Q000819:agonists / Q000378:metabolism
D000970:Antineoplastic Agents; D002227:Carbazoles; D004268:DNA-Binding Proteins; D006609:High Mobility Group Proteins; D016328:NF-kappa B; C073537:SSRP1 protein, human; D035602:Transcriptional Elongation Factors; D016159:Tumor Suppressor Protein p53; D004247:DNA