[Analysis of asbestos bodies and nude fibres in the lung parenchyma of operated lung cancers. A retrospective monocentric study of 73 cases].
We report on a study concerning a retrospective monocentric series of 73 lung cancers operated on between July 2004 and December 2009. All patients had a mineralogical analysis of a sample of lung tissue combined with an occupational questionnaire. This combination enables us to suggest a declaration of occupational exposure in almost one third of cases. We suggest that a healthy parenchymal fragment is to be obtained by biopsy routinely in cases of lung cancer surgery. The analysis should be carried out if the occupational survey does not demonstrate any evident exposure and if the patient is not known to be presenting a pleuropulmonary disease following asbestos exposure (pleural plaques and asbestosis).
Service de pneumologie, centre hospitalier Saint-Joseph-Saint-Luc, 20 quai Claude-Bernard, Lyon, France. mvincent@ch-stjoseph-stluc-lyon.fr
M
M
Vincent
G
G
Perrin
S
S
Vuillermoz-Blas
E
E
Laennec
A-S
AS
Blanchet
G
G
Frecon
F
F
Thivolet
E
E
Roux
C
C
Chemarin
D000328:Adult; D000368:Aged; D001194:Asbestos / Q000009:adverse effects / Q000032:analysis*; D001195:Asbestosis / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology / Q000473:pathology* / Q000601:surgery; D002277:Carcinoma / Q000150:complications / Q000453:epidemiology / Q000473:pathology* / Q000601:surgery; D015331:Cohort Studies; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D002479:Inclusion Bodies / Q000737:chemistry* / Q000473:pathology*; D008168:Lung / Q000473:pathology* / Q000601:surgery; D008175:Lung Neoplasms / Q000150:complications / Q000453:epidemiology / Q000473:pathology* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D019016:Mineral Fibers / Q000032:analysis; D016273:Occupational Exposure / Q000032:analysis / Q000706:statistics & numerical data; D012189:Retrospective Studies; D012907:Smoking / Q000009:adverse effects / Q000453:epidemiology
D019016:Mineral Fibers; D001194:Asbestos