[Clinical pharmacology in arthritis].
The definition of clinical pharmacology in arthritis includes different levels of measures of the clinical activity and the anatomical. The clinical measure of osteoarthritis (OA) is well validated and includes the measures of pain, disability and quality of life. Those measures should be adapted to each localisation of osteoarthritis. The measure of structural evolution of OA could be approached by the dosage in the serum of biomarkers. Several have shown some interests but none is validated in clinical practice.
Service de Rhumatologie, Hopital Henri Mondor, Creiteil, France. xavier.chevalier@hmn.aphp.fr
Xavier
X
Chevalier
D001168:Arthritis / Q000150:complications / Q000188:drug therapy* / Q000473:pathology / Q000523:psychology; D015415:Biomarkers; D004185:Disability Evaluation; D005385:Fingers / Q000473:pathology; D006801:Humans; D010003:Osteoarthritis / Q000150:complications / Q000188:drug therapy; D010146:Pain / Q000209:etiology; D010147:Pain Measurement; D010597:Pharmacogenetics; D011788:Quality of Life
D015415:Biomarkers