[One new lignan glycoside from whole plants of Senecio chrysanthemoides].
OBJECTIVE
To investigate the chemical constituents from the whole plants of Senecio chrysanthemoides.


METHODS
Constituents were isolated by using a combination of various chromatographic techniques including column chromatography over silica gel, Sephadex LH-20, and ODS C18, as well as reversed-phase HPLC. Structures of the isolates were identified by spectroscopic and chemical methods.


RESULTS
Eighteen glycosides were obtained from a H2O-soluble portion of an ethanolic extract of the whole plants of Senecio chrysanthemoides and their structures were elucidated as 5'-methoxyligusinenoside B (1), hyuganoside III b (2), citrusin A (3), alaschanioside A (4), citrusin B (5), dehydrodieoniferyl alcohol 4, gamma'-di-O-beta-D-glucopyranoside (6), osmanthuside G (7), syringin (8), dehydrosyringin (9), 2-(4-hydroxy-3,5-dimethoxyphenyl) ethanol 4-O-beta-D-glucopyranoside (10), 2-phenylethyl beta-gentiobioside (11), phenethyl beta-D-glucopyranoside (12), nikoenoside (13), benzyl beta-D-glucopyranoyl (1 --> 6 ) -beta-D-glucopyranoside (14), 3,5-dimethoxy-4-hydroxybenzyl alcohol 4-O-beta-D-glucopyranoside (15), icariside B2 (16), sonchuionoside C (17), and 1-[(beta-D-glucopyranosyloxy) methyl] -5,6-dihydropyrrolizin-7-one (18).


CONCLUSIONS
Compound 1 was a new lignan glycoside, and the remaining compounds were obtained from this plant for the first time.
College of Pharmacy, Second Military Medical University, Shanghai 200433, China.
Sheng
S
Lin
Zhongxiao
Z
Zhang
Yunheng
Y
Shen
Huiliang
H
Li
Lei
L
Shan
Runhui
R
Liu
Xike
X
Xu
Weidong
W
Zhang
D002845:Chromatography / Q000379:methods; D006027:Glycosides / Q000737:chemistry* / Q000302:isolation & purification; D017705:Lignans / Q000737:chemistry* / Q000302:isolation & purification; D010936:Plant Extracts / Q000737:chemistry*; D010946:Plants, Medicinal / Q000737:chemistry; D012674:Senecio / Q000737:chemistry*
C584928:5'-methoxyligusinenoside B; D006027:Glycosides; D017705:Lignans; D010936:Plant Extracts