Activating L265P mutations of the MYD88 gene are common in primary central nervous system lymphoma.
Manuel
M
Montesinos-Rongen
Elzbieta
E
Godlewska
Anna
A
Brunn
Otmar D
OD
Wiestler
Reiner
R
Siebert
Martina
M
Deckert
D000328:Adult; D000368:Aged; D001706:Biopsy; D053468:CARD Signaling Adaptor Proteins / Q000235:genetics / Q000502:physiology; D016543:Central Nervous System Neoplasms / Q000235:genetics* / Q000473:pathology / Q000503:physiopathology; D005260:Female; D006162:Guanylate Cyclase / Q000235:genetics / Q000502:physiology; D006801:Humans; D053592:Interleukin-1 Receptor-Associated Kinases / Q000502:physiology; D008223:Lymphoma / Q000235:genetics* / Q000473:pathology / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D009154:Mutation / Q000235:genetics*; D053594:Myeloid Differentiation Factor 88 / Q000235:genetics* / Q000502:physiology; D016328:NF-kappa B / Q000502:physiology; D012189:Retrospective Studies; D015398:Signal Transduction / Q000235:genetics* / Q000502:physiology; D051193:Toll-Like Receptors / Q000502:physiology
D053468:CARD Signaling Adaptor Proteins; C507779:MYD88 protein, human; D053594:Myeloid Differentiation Factor 88; D016328:NF-kappa B; D051193:Toll-Like Receptors; C507773:IRAK4 protein, human; D053592:Interleukin-1 Receptor-Associated Kinases; C426242:CARD11 protein, human; D006162:Guanylate Cyclase