Pseudodysplastic regenerative mucosa associated with congenital ileal atresia.
A male neonate was clinically diagnosed with congenital intestinal atresia. Surgical operation was performed and the ileum including the atretic portion was resected. Grossly, there was a plaque-like elevation of mucosa at the proximal side of the ileal atresia. Microscopic examination of this lesion revealed proliferation of severely atypical glands. Although dysplasia was a serious diagnostic concern, we concluded that ischemia due to the intestinal atresia induced this benign pseudodysplastic regenerative mucosa, judging from the pattern of coexisting inflammation and the literature review.
Department of Pathology, Medical Research Institute, Kitano Hospital, Osaka, Japan. fujimasa@kuhp.kyoto-u.ac.jp
Masakazu
M
Fujimoto
Hiromi
H
Sakashita
Kengo
K
Hattori
Yuya
Y
Miyauchi
Mari
M
Sonoda
Masahito
M
Sato
Yoshiaki
Y
Yuba
D003937:Diagnosis, Differential; D006801:Humans; D007082:Ileum / Q000002:abnormalities* / Q000098:blood supply; D007231:Infant, Newborn; D007409:Intestinal Atresia / Q000150:complications* / Q000473:pathology / Q000601:surgery; D007413:Intestinal Mucosa / Q000098:blood supply / Q000473:pathology*; D007421:Intestine, Small / Q000002:abnormalities* / Q000473:pathology / Q000601:surgery; D007511:Ischemia / Q000209:etiology* / Q000473:pathology; D008297:Male