Retrospective analysis for thirty-nine patients with solitary fibrous tumor of pleura and review of the literature.
BACKGROUND
Solitary fibrous tumor of the pleura (SFTP) is an uncommon neoplasm arising from mesenchymal cells. The aim of this study is to summarize the experience and the outcome of the surgical treatment for 39 cases of SFTP.


METHODS
From January 2004 to December 2008, 39 patients underwent surgical resection of SFTP in our department. All patients had clinical follow-up by the same team of surgeons. The mean follow-up was 40.3 months.


RESULTS
A local removal of the neoplasm was accomplished by video-assisted thoracic surgery (VATS) in 9 patients (group A) and by thoracotomy in 30 patients (group B) respectively. Comparing with group B, operations in group A took significantly less operative time, blood loss and spent less time in the intensive care unit and hospital. All specimens were positive for CD34 and Bcl-2. One patient developed recurrence, and the remaining 38 patients are alive and disease free at the end of follow-up.


CONCLUSIONS
Malignant SFTP still had the potential recurrence. VATS represents the more acceptable choice for the selected patients with SFTP.
Department of Thoracic Surgery, Institute of Surgery Research, Daping Hospital, Third Military Medical University, Changjiang Route 10#, Chongqing, PR China.
Wei
W
Guo
Hua-Liang
HL
Xiao
Yao-Guang
YG
Jiang
Ru-Wen
RW
Wang
Yun-Ping
YP
Zhao
Zheng
Z
Ma
Hui-Jun
HJ
Niu
D000328:Adult; D000368:Aged; D014408:Biomarkers, Tumor / Q000032:analysis; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007124:Immunoenzyme Techniques; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000473:pathology / Q000601:surgery*; D009367:Neoplasm Staging; D011379:Prognosis; D012189:Retrospective Studies; D012196:Review Literature as Topic; D054363:Solitary Fibrous Tumor, Pleural / Q000473:pathology / Q000601:surgery*; D020775:Thoracic Surgery, Video-Assisted; D055815:Young Adult
D014408:Biomarkers, Tumor