[The key target of Chinese medicine treatment on alcoholic and nonalcoholic fatty liver disease: the gut].
In recent years, the pathogenesis of "gut-liver axis" in alcoholic and nonalcoholic fatty liver disease has attracted more attention in this field. In this paper, the relationship among fatty liver, gut-permeability, gut-derived endotoxin, and gut microbiota was systematically clarified. Based on the researches of treatment and prevention of fatty liver and gut injury by Chinese medicine, the gut is believed as the curative target for fatty liver disease, which not only is the modern annotation for the Chinese medicine practice, but also might possibly become an important view angle and strategy for fatty liver disease treatment.
Institute of Liver Diseases, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 201203. yyhuliver@163.com
Yi-yang
YY
Hu
Jing-hua
JH
Peng
Qin
Q
Feng
D004365:Drugs, Chinese Herbal / Q000008:administration & dosage / Q000627:therapeutic use*; D005234:Fatty Liver / Q000209:etiology / Q000628:therapy*; D041981:Gastrointestinal Tract; D006801:Humans; D008516:Medicine, Chinese Traditional / Q000379:methods; D065626:Non-alcoholic Fatty Liver Disease; D008517:Phytotherapy / Q000379:methods*
D004365:Drugs, Chinese Herbal