Light signaling mediated by PAS domain-containing proteins in Xanthomonas campestris pv. campestris.
Per-ARNT-Sim (PAS) domains are important signalling modules that possibly monitor changes in various stimuli such as light. For the majority of PAS domains that have been identified by sequence similarity, the biological function of the signalling pathways has not yet been experimentally investigated.Thirty-three PAS proteins were discovered in Xanthomonas campestris pv. campestris(Xcc) by genome/proteome analysis. Thirteen PAS proteins were identified as contributing to light signalling and Xcc growth, motility or virulence using molecular genetics and bioinformatics methods. The PAS domains played important roles in light signalling to regulate the growth, motility and virulence of Xcc. They might be regulated by not only light quality (wavelength)but also quantity (intensity) as potential light-signalling components. Evaluating the light wavelength, three light-signalling types of PAS proteins in Xcc were shown to be involved in blue light signalling, tricolour (blue, red and far red)signalling or red/far-red signalling. This showed that Xcc had evolved a complicated light-signalling system to adapt to a complex environment.
School of Life Sciences, Tsinghua University, Beijing, China.
Daqing
D
Mao
Jun
J
Tao
Chunxia
C
Li
Chao
C
Luo
Linlin
L
Zheng
Chaozu
C
He
D000222:Adaptation, Physiological; D001426:Bacterial Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D001937:Brassica / Q000382:microbiology; D016000:Cluster Analysis; D019295:Computational Biology; D016680:Genome, Bacterial; D000071677:Histidine Kinase; D008027:Light; D055537:Light Signal Transduction; D009068:Movement; D009154:Mutation; D010802:Phylogeny; D010935:Plant Diseases / Q000382:microbiology; D054730:Protein Interaction Domains and Motifs; D011494:Protein Kinases / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D014157:Transcription Factors / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D016959:Xanthomonas campestris / Q000235:genetics / Q000254:growth & development / Q000472:pathogenicity / Q000502:physiology*
D001426:Bacterial Proteins; D014157:Transcription Factors; D011494:Protein Kinases; D000071677:Histidine Kinase