PNA to DNA to microarray decoding facilitates ligand discovery.
The development of a method for the amplification of PNA tags (Svensen et al., in this issue of Chemistry & Biology) should expand the range of biological targets amenable to screening using PNA-encoded combinatorial libraries and thus facilitate the discovery of new biologically useful agents.
Department of Chemistry University of Cambridge, Cambridge CB2 1EW, UK.
Warren R J D
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Galloway
David R
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Spring