Molecular patterning at a liquid/solid interface: the foldamer approach.
Molecular patterning has received a lot of attention in the past decade; however, the functionalization of these surface-confined 2D patterns on the nanoscale level remains a challenge. Assembling 2D patterns from oligomeric foldamers turns out to be an interesting approach to accomplishing the controlled positioning of functional elements. We designed a family of peptidomimetic foldamers bearing a 2D turn element folding at the liquid/solid interface. The turning element was developed while studying derivatives with one turning unit. Furthermore, folding was found to be induced by the confinement of the surface. This achievement paves the way for the design of foldamers with multiple turns, providing a higher versatility in the functionalization of nanopatterns.
Department of Chemistry, Division of Molecular Imaging and Photonics, Katholieke Universiteit Leuven, Celestijnenlaan 200F, 3001 Leuven, Belgium.
Min
M
Li
Cristian
C
Gobbo
Inge
I
De Cat
Rienk
R
Eelkema
Bernard
B
Vanaverbeke
Roberto
R
Lazzaroni
Steven
S
De Feyter
Jan
J
van Esch