Microbial ecology of swine farms and PRRS vaccine vaccination strategies.
The present study investigated the microbial ecology and vaccination strategies against porcine reproductive and respiratory syndrome (PRRS) in field condition. Four representative farms with a history of PRRS were included in this study. Over the almost 3-year period, the average detection rate was 68.9%, making PRRSV the first most frequently detected virus, followed by porcine circovirus type 2 (PCV2) (64.2%), pseudorabies virus (PRV) (11.03%) and classical swine fever virus (CSFV) (4.41%). Streptococcus suis (77.92%), Haemophilus parasuis (51.25%) and Escherichia coli (52.39%), Pasteurella multocida (26.77%) were isolated most frequently in association with PRRSV. Under the present microbial ecology, production performances of sows their offspring after mass vaccination with a PRRS attenuated vaccine were evaluated. In addition, large scale PRRS vaccines usage and efficacy were further performed. The results indicated that mass vaccination following our immunization program can improve health status and production performances of both sows (2ml/i.m. booster after 4 weeks, and then immunized quarterly) and their offsprings (1ml/i.m. on 14-18 days of age).
Beijing Institute of Animal Husbandry and Veterinary Medicine, Chinese Academy of Agricultural Sciences, Beijing 100193, People's Republic of China.
Zhanzhong
Z
Zhao
Yuming
Y
Qin
Zhi
Z
Lai
Liying
L
Peng
Xuehui
X
Cai
Liyong
L
Wang
Xin
X
Guo
Hanchun
H
Yang
D000818:Animals; D017925:Circovirus / Q000302:isolation & purification; D011558:Herpesvirus 1, Suid / Q000302:isolation & purification; D008297:Male; D019318:Porcine Reproductive and Respiratory Syndrome / Q000175:diagnosis / Q000517:prevention & control* / Q000821:virology*; D019316:Porcine respiratory and reproductive syndrome virus / Q000276:immunology* / Q000302:isolation & purification; D013552:Swine; D014611:Vaccination / Q000662:veterinary; D014613:Vaccines, Attenuated / Q000276:immunology; D014765:Viral Vaccines / Q000276:immunology
D014613:Vaccines, Attenuated; D014765:Viral Vaccines