Palatal ulceration as the first sign of pulmonary tuberculosis: a case report.
Tuberculosis (TB) is one of the leading casues of morbidity and death in a number of countries worldwide. A healthy 42-year-old patient presented with a chronic palatal ulcer that was not responsive to routine antibiotic treatment. A biopsy and further systemic investigation revealed a diagnosis of TB. An eight-month extended course of oral rifampin and isoniazid was instituted successfully resulting in complete resolution of symptoms. It is important that clinicians be aware that chronic oral ulcerations may be the first sign of systemic disease. A biopsy should therefore be mandatory for any chronic oral ulcer not responsive to conventional treatment.
Department of Oral Medicine and Periodontology, University of the Western Cape, Private Bag X1, Tygerberg 7505, Cape Town, South Africa. 9552379@uwc.ac.za
Mogammad Thabit
MT
Peck
Lawrence X G
LX
Stephen
Johan
J
Marnewick
Abdul
A
Majeed
D000328:Adult; D000995:Antitubercular Agents / Q000627:therapeutic use; D002908:Chronic Disease; D006801:Humans; D007538:Isoniazid / Q000627:therapeutic use; D008297:Male; D009061:Mouth Mucosa / Q000382:microbiology / Q000473:pathology; D009169:Mycobacterium tuberculosis / Q000187:drug effects / Q000302:isolation & purification*; D019226:Oral Ulcer / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology* / Q000473:pathology; D012293:Rifampin / Q000627:therapeutic use; D016896:Treatment Outcome; D014393:Tuberculosis, Oral / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology / Q000473:pathology; D014397:Tuberculosis, Pulmonary / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology
D000995:Antitubercular Agents; D007538:Isoniazid; D012293:Rifampin