Template-directed RNA polymerization: the taming of the milieu.
No-bias binding: The abiotic template-directed synthesis of RNA could have been a key process in the origins of life on Earth. Recreating this process in the laboratory has been challenging, yet a combination of strategies has given rise to a synthesis that is both efficient and unbiased against any of the four nucleotides.
Department of Chemistry, Portland State University, P. O. Box 751, Portland, OR 97207, USA. niles@pdx.edu
Niles
N
Lehman
Eric J
EJ
Hayden
D001704:Biopolymers / Q000737:chemistry*; D012313:RNA / Q000737:chemistry* / Q000235:genetics; D013698:Templates, Genetic
D001704:Biopolymers; D012313:RNA