[Ependymomas of the lateral ventricle. A series of 27 cases with review of the literature].
Twenty-seven cases of ependymoma were collected in the French multicentric study dedicated to lateral ventricle tumors. The mean age of patients was 31,5 years. All patients underwent surgery, with complete resection of the tumor in 76% of cases. Histologic examination disclosed 23 grade 2 ependymomas and four grade 3 ependymomas. Postoperative mortality was 7%. Four patients underwent radiotherapy, and five chemotherapy. Local recurrence of the tumor occurred in seven cases, with a mean delay of 48 months. Disseminated disease within the central nervous system was found in only one patient. Median survival in all the 27 patients was 181 months, and median progression-free survival was 106 months. The relevant series of the literature are reviewed in order to precise the prognostic factors of ependymomas and therapeutic strategies.
Clinique de neurochirurgie, hôpital Roger-Salengro, rue Émile-Laine, CHRU de Lille, 59037 Lille cedex, France. jeanpaul.lejeune@chru-lille.fr
J-P
JP
Lejeune
N
N
Reyns
M
M
Baroncini
J
J
Peltier
D
D
Le Gars
D000293:Adolescent; D000328:Adult; D000368:Aged; D002551:Cerebral Ventricle Neoplasms / Q000150:complications / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D002648:Child; D002675:Child, Preschool; D003131:Combined Modality Therapy; D018450:Disease Progression; D018572:Disease-Free Survival; D004806:Ependymoma / Q000150:complications / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D005260:Female; D005602:France; D006801:Humans; D007223:Infant; D020547:Lateral Ventricles / Q000473:pathology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D019635:Neurosurgical Procedures / Q000379:methods*; D016019:Survival Analysis; D016896:Treatment Outcome; D055815:Young Adult