Ruthenium-catalysed oxidative synthesis of heterocycles from alcohols.
Ruthenium-catalysed hydrogen transfer has been successfully used for the conversion of alcohols into either 2,3-dihydroquinazolines or quinazolines. The choice of reaction conditions allows for the selective formation of either heterocycle and the methodology can also be applied to the sulfonamide analogue.
Department of Chemistry, University of Bath, Claverton Down, Bath, UK BA2 7AY. ajaw20@bath.ac.uk
Andrew J A
AJ
Watson
Aoife C
AC
Maxwell
Jonathan M J
JM
Williams
D000438:Alcohols / Q000737:chemistry*; D002384:Catalysis; D006571:Heterocyclic Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D010084:Oxidation-Reduction; D012428:Ruthenium / Q000737:chemistry*
D000438:Alcohols; D006571:Heterocyclic Compounds; D009942:Organometallic Compounds; D012428:Ruthenium