Memory: the incomplete unhappening of differentiation.
The signals that regulate the differentiation of central and effector memory T cells remain unclear. In this issue of Immunity, Pepper et al. (2011) and Marshall et al. (2011) implicate the differential expression of transcription factors in driving memory subtypes.
Department of Medicine, Division of Allergy, Immunology and Rheumatology, University of Rochester, Rochester, NY 14642, USA.
André
A
Ballesteros-Tato
Troy D
TD
Randall