Superimposed linear psoriasis: a historical case revisited.
In 1978, a case of "ichthyosis vulgaris and ILVEN syndrome (inflammatory linear verrucous epidermal nevus)" was presented by Johannes Ring, of Munich [1]. Based on present knowledge, a diagnosis of superimposed linear psoriasis appears simpler and more appropriate because the 10-year-old girl also had multiple psoriatic plaques, with a symmetrical and non-segmental distribution. The linear manifestation most likely reflects the clonal outgrowth of a population of cells harboring a postzygotic mutation that increased the predisposition to psoriasis.
Department of Dermatology, Freiburg University Medical Center, Freiburg, Germany. rudolf.happle@uniklinik-freiburg.de
Rudolf
R
Happle
D002648:Child; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D011565:Psoriasis / Q000145:classification* / Q000175:diagnosis*; D009626:Terminology as Topic