Translation, cross-cultural adaptation and validation of SinoNasal Outcome Test (SNOT): 22 to Brazilian Portuguese.
Quality of life questionnaires have been increasingly used in clinical trials to help establish the impact of medical intervention or to assess the outcome of health care services. Among disease-specific outcome measures, SNOT-22 was considered the most suitable tool for assessing chronic rhinosinusitis and patients with nasal polyps.


OBJECTIVE
To perform translation, cross-cultural adaptation and validation of the SNOT-22 to Brazilian Portuguese.


METHODS
Prospective study involving eighty-nine patients with chronic rhinosinusitis or nasal polyps submitted to functional endoscopic sinus surgery, who answered the questionnaire before and after surgery. Furthermore, 113 volunteers without sinonasal disease also answered the questionnaire. Internal consistency, test-retest reliability, measure validity, responsiveness and clinical interpretability were assessed.


RESULTS
Mean preoperative, postoperative and no sinonasal disease scores were 62.39, 23.09 and 11.42, respectively (p<0.0001); showing validity and responsiveness. Internal consistency was high (Cronbach's alpha = 0.9276). Reliability was sufficiently good, considering inter-interviewers (r=0.81) and intra-interviewers within a 10 to 14 day-interval (r=0.72). Surgery effect size was 1.55. Minimally important difference was 14 points; and scores up to 10 points were considered normal.


CONCLUSIONS
The Brazilian Portuguese SNOT-22 version is a valid instrument to assess patients with chronic rhinosinusitis and nasal polyps.
ENT Residency Program, Paulista School of Medicine, Federal University of São Paulo. edumacoto@uol.com.br
Eduardo Macoto
EM
Kosugi
Vitor Guo
VG
Chen
Viviane Maria Guerreiro da
VM
Fonseca
Milena Martins Pellogia
MM
Cursino
José Arruda
JA
Mendes Neto
Luís Carlos
LC
Gregório
D000293:Adolescent; D000328:Adult; D000368:Aged; D001938:Brazil; D016022:Case-Control Studies; D002908:Chronic Disease; D003466:Cultural Characteristics; D005260:Female; D006801:Humans; D007802:Language; D008297:Male; D008875:Middle Aged; D009298:Nasal Polyps / Q000523:psychology / Q000601:surgery*; D011446:Prospective Studies; D011788:Quality of Life; D012220:Rhinitis / Q000523:psychology / Q000601:surgery*; D012852:Sinusitis / Q000523:psychology / Q000601:surgery*; D011795:Surveys and Questionnaires; D014175:Translating; D016896:Treatment Outcome; D055815:Young Adult