[Synthetic treatment of malignant tumor of nasal cavity and sinus based-on modern technique radiotherapy].
OBJECTIVE
To evaluate the therapeutic effect of malignant tumor of nasal cavity and sinus that based on modern radiotherapy.


METHODS
Two hundred cases of malignant tumor of nasal cavity and sinus were retrospectively analyzed from 2004 to 2007. All the cases were location by CT simulator system and were treated with three dimensional conformal radiotherapy.


RESULTS
Among malignant tumor of nasal cavity and sinus, the incidence for locations was nasal cavity > maxillary sinus > ethmoid sinus > sphenoid sinus; the incidence for the type of pathology was squamous cell carcinoma > adenocarcinoma > olfactory neuroblastoma and olfactory esthesioneuroepithelioma > malignant melanoma > rhabdomyosarcoma; the incidence for general metastasis was rhabdomyosarcoma > malignant melanoma > adenocarcinoma, inverted papilloma and malignant changes > squamous cell carcinoma, olfactory neuroblastoma and olfactory esthesioneuroepithelioma. No severe radiation-related complication were found.


CONCLUSIONS
Clinical stage, pathological type were the important factors effecting the prognosis of patients with malignant tumor of nasal cavity and sinus. Three dimensional conformal radiotherapy based on CT simulator system could improve therapeutic effect and protect the normal tissue very well.
Department of Radiation Oncology, Eye Ear Nose Throat Hospital of Fudan University, Shanghai 200031, China shengziwang@yahoo.com
Shengzi
S
Wang
Fu
F
Chen
Ji
J
Li
Haiyan
H
Zhang
Lifen
L
Zou
Shuyi
S
Wang
Ming
M
Guo
Gang
G
Yang
D000230:Adenocarcinoma / Q000473:pathology / Q000532:radiotherapy; D000293:Adolescent; D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000532:radiotherapy; D018304:Esthesioneuroblastoma, Olfactory / Q000473:pathology / Q000532:radiotherapy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009296:Nasal Cavity; D009669:Nose Neoplasms / Q000473:pathology / Q000532:radiotherapy*; D010255:Paranasal Sinus Neoplasms / Q000473:pathology / Q000532:radiotherapy*; D011379:Prognosis; D020266:Radiotherapy, Conformal / Q000379:methods*; D012189:Retrospective Studies; D015996:Survival Rate; D055815:Young Adult