Transcutaneous ultrasound for evaluation of vocal fold movement in patients with thyroid disease.
BACKGROUND
Preoperative evaluation of recurrent laryngeal nerve function is important in the context of thyroid surgery. Transcutaneous ultrasound may be useful to visualize vocal fold movement when evaluating thyroid disease.


METHODS
A 7-18 MHz linear array transducer was placed transversely on the midline of the thyroid cartilage at the anterior neck of patients with thyroid disease. The gray-scale technique was used, with the scan setting for the thyroid gland.


RESULTS
Between August 2008 and March 2010, 705 patients, including 672 patients with normal vocal fold movement and 33 patients with vocal fold paralysis were enrolled. They included 159 male and 546 female patients. Their ages ranged from 10 to 88 years. Vocal fold movement could be seen by ultrasound in 614 (87%) patients, including 589 (88%) patients with normal vocal fold movement and 25 (76%) patients with vocal fold paralysis (p=0.06). The mean age of patients with visible and invisible vocal fold movement was 46.6 and 57.9 years old, respectively (p=0.001). Ultrasound was able to see vocal fold movement in 533 (98%) female patients but only in 81 (51%) male patients (p=0.001). Among the patients with vocal fold paralysis, ultrasound revealed palsied vocal folds in 17 of 18 (94%) female patients but in only 8 of 15 (53%) male patients (p=0.01).


CONCLUSIONS
Transcutaneous ultrasound represents an alternative tool to evaluate vocal fold movement for more than 85% of patients with thyroid disease, including more than 90% of female patients and about half of male patients.
Institute of Biomedical Engineering, College of Medicine, National Taiwan University, and Department of Otolaryngology, National Taiwan University Hospital, Taipei, Taiwan. wangcp@ntu.edu.tw
Cheng-Ping
CP
Wang
Tseng-Cheng
TC
Chen
Tsung-Lin
TL
Yang
Chun-Nan
CN
Chen
Chin-Fon
CF
Lin
Pei-Jen
PJ
Lou
Ya-Ling
YL
Hu
Ming-Jium
MJ
Shieh
Fon-Jou
FJ
Hsieh
Tzu-Yu
TY
Hsiao
Jenq-Yuh
JY
Ko
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012009:Recurrent Laryngeal Nerve / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D013959:Thyroid Diseases / Q000503:physiopathology*; D014159:Transducers; D014463:Ultrasonography; D014826:Vocal Cord Paralysis / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D014827:Vocal Cords / Q000000981:diagnostic imaging* / Q000503:physiopathology*