Acoustic radiation force impulse elastography and contrast-enhanced sonography of sinusoidal obstructive syndrome (Veno-occlusive Disease): preliminary results.
We report quantitative liver acoustic radiation force impulse (ARFI) elastographic findings in 2 cases of sinusoidal obstructive syndrome and liver contrast-enhanced sonographic features in one of these cases. To our knowledge, findings in this condition from these techniques have not been reported previously. Acoustic radiation force impulse elastography showed median high shear wave velocities (case 1, 2.75 m/s; case 2, 2.58 m/s) that normalized after specific treatment for sinusoidal obstructive syndrome; therefore, ARFI elastography provided quantitative information that helped diagnose this condition as well as monitor the response to treatment. Contrast-enhanced sonographic findings in one of the cases showed patchy liver enhancement that correlated with the high-velocity patchy distribution on ARFI elastography in that case and enhanced multidetector row computed tomographic findings in the other case. This contrast-enhanced sonographic pattern progressively normalized during follow-up after specific treatment. The elastographic features in both cases and contrast-enhanced sonographic features in one of them contributed to early diagnosis and follow-up of sinusoidal obstructive syndrome in both patients. Further prospective studies are necessary to define the role of ARFI elastography and contrast-enhanced sonography in the early diagnosis and clinical follow-up of this condition.
Departments of Diagnostic Radiology, Puerta de Hierro Majadahonda University Hospital, Madrid, Spain. tfontanilla@telefonica.net
Teresa
T
Fontanilla
Concepción González
CG
Hernando
Juan Cristóbal Valenzuela
JC
Claros
Guiomar
G
Bautista
Javier
J
Minaya
Maria
M
Del Carmen Vega
Ana
A
Piazza
Santiago
S
Méndez
Claudio
C
Rodriguez
Rafael Pérez
RP
Arangüena
D000162:Acoustics; D003287:Contrast Media; D054459:Elasticity Imaging Techniques / Q000379:methods*; D005260:Female; D006504:Hepatic Veno-Occlusive Disease / Q000000981:diagnostic imaging*; D006801:Humans; D008875:Middle Aged
D003287:Contrast Media