Clinical analysis of patients with autoimmune disease complicated by mesenteric vein thrombosis: a retrospective study in a hospital.
OBJECTIVE
To analyze the clinical characteristics of patients with mesenteric venous thrombosis related to autoimmune disease (AID).


METHODS
Retrospective study of 5 AID patients with mesenteric vein thrombosis in a single hospital.


RESULTS
All 5 patients were female with an average age of 57.6 years. At the clinical visit all patients had clinical manifestations with signs of mesenteric blood vessel involvement and a significant increase of inflammatory markers. Surgical exploration identified peritonitis in all 5 cases - 2 cases of intestinal stenosis with mucosal ulcers and 3 cases of intestinal necrosis complicated by perforation. All 5 patients underwent partial bowel resection. Pathological examination confirmed chronic inflammation and vasculitis of intestinal connective tissue, combined with the formation of mesenteric vein thrombosis.


CONCLUSIONS
Mesenteric vein thrombosis is a serious complication of AID. AID patients with digestive tract symptoms should be screened by abdominal imaging. In addition to early hormonal therapy and immunosuppressant treatment of the primary disease, surgical treatment should be performed as soon as possible if the disease progresses.
Department of Rheumatology and Immunology, Capital Medical University, Beijing, China.
Wen
W
Luo
Mingwei
M
Li
Jing
J
Luo
Yueming
Y
He
D000328:Adult; D000368:Aged; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D001327:Autoimmune Diseases / Q000150:complications* / Q000175:diagnosis / Q000276:immunology / Q000401:mortality / Q000628:therapy; D001706:Biopsy; D002681:China; D013505:Digestive System Surgical Procedures; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006785:Hospitals, University; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D018836:Inflammation Mediators / Q000097:blood; D007511:Ischemia / Q000175:diagnosis / Q000209:etiology* / Q000276:immunology / Q000401:mortality / Q000628:therapy; D065666:Mesenteric Ischemia; D008641:Mesenteric Vascular Occlusion / Q000175:diagnosis / Q000209:etiology* / Q000276:immunology / Q000401:mortality / Q000628:therapy; D008642:Mesenteric Veins; D008875:Middle Aged; D011237:Predictive Value of Tests; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D014652:Vascular Diseases / Q000175:diagnosis / Q000209:etiology* / Q000276:immunology / Q000401:mortality / Q000628:therapy; D014656:Vascular Surgical Procedures; D020246:Venous Thrombosis / Q000175:diagnosis / Q000209:etiology* / Q000276:immunology / Q000401:mortality / Q000628:therapy
D000894:Anti-Inflammatory Agents, Non-Steroidal; D005938:Glucocorticoids; D007166:Immunosuppressive Agents; D018836:Inflammation Mediators