Complex systems, evolution, and animal models.
In this paper, we respond to arguments made concerning our position regarding animal models (Shelley, 2010) by briefly examining the fact that animals (human and nonhuman) are complex systems that have different evolutionary trajectories. This historical fact has implications for using animals as predictive models for human response to drugs and disease.
Americans For Medical Advancement, 2251 Refugio Rd, Goleta, CA 93117, USA. DrRayGreek@aol.com
Ray
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Greek
Niall
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Shanks
D000818:Animals; D005075:Biological Evolution; D006801:Humans; D023421:Models, Animal; D008954:Models, Biological; D013223:Statistics as Topic; D049490:Systems Biology