Serum trace elements and heavy metals in polycystic ovary syndrome.
OBJECTIVE
We aimed to investigate the serum levels of essential trace elements copper (Cu), zinc (Zn), manganese (Mn), magnesium (Mg) and heavy metals cadmium (Cd), cobalt (Co) and lead (Pb) in the patients with polycystic ovary syndrome (PCOS).


METHODS
A total of 65 (35 patients with PCOS and 30 healthy controls) women were included in the study. Serum Cu, Zn, Mn, Pb, Mg, Co and Cd levels were analyzed using atomic absorption spectrophotometric method.


RESULTS
Serum Cu and Zn levels were significantly higher, but Mn and Pb levels were lower in patients with PCOS compared with the healthy participants (p < 0.01). There was no difference between patients with PCOS and the controls with respect to the serum levels of Mg, Co and Cd.


CONCLUSIONS
This is the first study investigating serum Cu, Zn, Mn, Pb, Co, Mg and Cd levels in the patients with PCOS. The serum levels of trace elements and heavy metals might change in patients with PCOS. The findings in this study should be investigated with further trials in order to obtain new insights into PCOS.
Department of Obstetrics and Gynecology, Yuzuncu Yil University, Van, Turkey. zehrakurdoglu@hotmail.com
Z
Z
Kurdoglu
M
M
Kurdoglu
H
H
Demir
H G
HG
Sahin
D000328:Adult; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D019216:Metals, Heavy / Q000097:blood*; D011085:Polycystic Ovary Syndrome / Q000097:blood* / Q000453:epidemiology; D014131:Trace Elements / Q000097:blood*; D055815:Young Adult
D019216:Metals, Heavy; D014131:Trace Elements