Remission and recovery and their predictors in schizophrenia spectrum disorder: results from a 1-year follow-up naturalistic trial.
Remission and recovery are major outcome goals in schizophrenia yet their predictors have not been studied in detail. Therefore, 186 patients were examined regarding remission and recovery including their potential sociodemographic and clinical predictors 1 year after discharge. Remission was defined according to the consensus remission criteria and recovery following the definition by Liberman et al. (2002). Of the 186 patients 54% achieved remission and 26% recovery at the 1-year follow-up. The remission status at discharge was found to significantly influence remission and recovery at follow-up. A higher SOFAS score (P = 0.0002) as well as a positive attitude towards treatment at discharge (P = 0.0038) were identified to be significant predictors of remission at 1-year follow-up. Having a job (P = <0.0001) and being without pharmacological treatment at follow-up (P = 0.0113) were found to be significantly predictive of recovery. Our results underline the need to implement more specific treatment strategies to improve long-term outcome.
Department of Psychiatry and Psychotherapy, Ludwig-Maximilians-University Munich, Nussbaumstrasse 7, 80336, Munich, Germany. Rebecca.Schennach-Wolff@med.uni-muenchen.de
Rebecca
R
Schennach
Michael
M
Riedel
Michael
M
Obermeier
Markus
M
Jäger
Max
M
Schmauss
Gerd
G
Laux
Herbert
H
Pfeiffer
Dieter
D
Naber
Lutz G
LG
Schmidt
Wolfgang
W
Gaebel
Joachim
J
Klosterkötter
Isabella
I
Heuser
Wolfgang
W
Maier
Matthias R
MR
Lemke
Eckart
E
Rüther
Stefan
S
Klingberg
Markus
M
Gastpar
Florian
F
Seemüller
Hans-Jürgen
HJ
Möller
D000293:Adolescent; D000328:Adult; D000359:Aftercare / Q000706:statistics & numerical data; D000368:Aged; D004651:Employment / Q000706:statistics & numerical data; D005260:Female; D005500:Follow-Up Studies; D033062:Friends; D005858:Germany; D006801:Humans; D057187:Independent Living / Q000706:statistics & numerical data; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D017063:Outcome Assessment, Health Care / Q000706:statistics & numerical data*; D010349:Patient Compliance / Q000706:statistics & numerical data; D010351:Patient Discharge / Q000706:statistics & numerical data*; D011569:Psychiatric Status Rating Scales / Q000706:statistics & numerical data; D012074:Remission Induction; D012559:Schizophrenia / Q000534:rehabilitation*; D012565:Schizophrenic Psychology; D012720:Severity of Illness Index; D058992:Social Participation; D012944:Social Support; D012959:Socioeconomic Factors; D055815:Young Adult