[Correction of the immune disorders in patients with diabetes mellitus type II with complicated diabetic foot syndrome].
There were examined 86 patients, suffering mixed form of diabetic foot syndrome. In all the patients diabetes mellitus type II was diagnosed, the disease duration have constituted (12.3 +/- 2.5) yrs at average. The immune status was estimated, using determination of the lymphocytes subpopulations with the help of the monoclonal antibodies towards antigens reaction by the flowcytometry method, as well as concentration of the main classes of immunoglobulins IgA, IgM, IgG. The investigation was performed in dynamics: immediately after a patient admittance to hospital, on the 7 - 8th, 12 - 16th and 25 - 30th day. Basing on the analysis of the data obtained, there was conclusion made, that immediately after admittance to the hospital in the patients, suffering complicated diabetic foot syndrome, the disorders of cellular immunity of degree II and of humoral immunity of I degree were revealed. The indices improvement were noted while application of certain immunocorrecting therapy.
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Savon
D000119:Acetylmuramyl-Alanyl-Isoglutamine / Q000008:administration & dosage / Q000031:analogs & derivatives / Q000627:therapeutic use; D015703:Antigens, CD / Q000276:immunology; D003131:Combined Modality Therapy; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000276:immunology / Q000628:therapy*; D017719:Diabetic Foot / Q000209:etiology / Q000276:immunology / Q000628:therapy*; D004359:Drug Therapy, Combination; D005434:Flow Cytometry; D006801:Humans; D007154:Immune System Diseases / Q000276:immunology / Q000628:therapy*; D007111:Immunity, Cellular / Q000187:drug effects; D056724:Immunity, Humoral / Q000187:drug effects; D007136:Immunoglobulins / Q000097:blood; D007155:Immunologic Factors / Q000008:administration & dosage / Q000627:therapeutic use; D018655:Lymphocyte Count; D008875:Middle Aged; D013601:T-Lymphocytes / Q000166:cytology / Q000187:drug effects / Q000276:immunology; D016896:Treatment Outcome
D015703:Antigens, CD; D007136:Immunoglobulins; D007155:Immunologic Factors; C089161:glikopin; D000119:Acetylmuramyl-Alanyl-Isoglutamine