Delirium in the intensive care unit: a review.
Delirium occurs commonly in both general medical and intensive care unit (ICU) patients, with prevalence rates of up to 80% reported. A common expression of acute brain dysfunction, it is related to wide-ranging untoward outcomes such as prolonged hospitalization, increased costs, higher mortality, and, potentially long-term cognitive impairment. Different risk factors are associated with delirium, including sedation, which has implications for patient management. Multicomponent interventions to prevent delirium, developed in the non-ICU setting, can be adapted to critically ill patients with the purpose of reducing its incidence. Future studies should evaluate target interventions to prevent delirium in the ICU.
Center for Health Services Research, Vanderbilt Medical Center, 1215 21st Avenue South MCE Suite 6100, Nashville, TN 37232-1269, USA. morandi.alessandro@gmail.com
Alessandro
A
Morandi
James C
JC
Jackson
D003693:Delirium / Q000191:economics / Q000209:etiology / Q000401:mortality / Q000628:therapy*; D006801:Humans; D007249:Inflammation / Q000150:complications; D007362:Intensive Care Units; D059906:Neuroimaging; D012307:Risk Factors; D018805:Sepsis / Q000150:complications