[The neuropsychology of nigrostriatal dopaminergic transmission in Parkinson's disease].
Through cortico-subcortico-cortical loop systems, the dopaminergic modulation influences not only motor, but also other executive functions. Neuropsychological findings in Parkinson's disease are reviewed and physiologically interpreted. The theory of a "supervisory attentional system" according to Norman and Shallice (1986) seems to be an adequate model of the interaction of cortex and basal ganglia in executive function and control.
BDH-Klinik Elzach, Am Tannwald 179215 Elzach, Germany. cwallesch@neuroklinik-elzach.de
C
C
Wallesch
D001288:Attention / Q000502:physiology; D001479:Basal Ganglia / Q000503:physiopathology; D003342:Corpus Striatum / Q000503:physiopathology*; D004298:Dopamine / Q000502:physiology*; D056344:Executive Function; D006801:Humans; D007858:Learning / Q000502:physiology; D008568:Memory / Q000502:physiology; D009068:Movement / Q000502:physiology; D009484:Neuropsychology; D010300:Parkinson Disease / Q000503:physiopathology* / Q000523:psychology*; D011597:Psychomotor Performance / Q000502:physiology; D013378:Substantia Nigra / Q000503:physiopathology*; D009435:Synaptic Transmission / Q000502:physiology*
D004298:Dopamine