Stimulation on demand: closing the loop on deep brain stimulation.
High-frequency open-loop deep brain stimulation (DBS) has been used to alleviate Parkinson's symptoms for almost 20 years. In this issue of Neuron, Rosin et al. present a closed-loop real-time approach that improves DBS and shines light on the etiology of motor symptoms in Parkinson's disease.
Champalimaud Neuroscience Programme at Instituto Gulbenkian de Ciência, Rua da Quinta Grande, 2780-901 Oeiras, Portugal.
Fernando J
FJ
Santos
Rui M
RM
Costa
Fatuel
F
Tecuapetla
D000818:Animals; D001479:Basal Ganglia / Q000503:physiopathology*; D046690:Deep Brain Stimulation / Q000379:methods*; D005917:Globus Pallidus / Q000503:physiopathology*; D010302:Parkinson Disease, Secondary / Q000628:therapy*