Symptom clusters and quality of life in older adult breast cancer survivors.
OBJECTIVE
To identify symptom clusters in older adult breast cancer survivors (ages 65-97 years) and examine whether symptom clusters are related to demographic, health, and quality-of-life variables.


METHODS
Factor analysis to identify possible symptom clusters. The resulting clusters then were correlated with quality-of-life measures.


METHODS
Phone interviews between the participants and a trained research nurse.


METHODS
192 breast cancer survivors (X age = 70).


METHODS
This was a secondary data analysis of the baseline measures of demographics, health history, symptom bother, and physical, mental, and existential dimensions of quality of life. Exploratory and confirmatory factor analyses were conducted as well as multiple indicator multiple cause modeling and partial correlation analyses to assess the relationships among clusters and demographic, health history, and quality-of-life measures.


METHODS
Self-reported symptom bother, demographics such as age and education level, health history, and quality of life.


RESULTS
Seven clinically distinct symptom clusters tapping 36 different symptoms in older adult breast cancer survivors were found. These symptom clusters were significantly related to multiple dimensions of quality of life.


CONCLUSIONS
Older adult breast cancer survivors experience multiple concurrent symptoms that appear to cluster. Identifying symptom clusters helps to elucidate possible intersymptom relationships which may lead to the design of more effective symptom management interventions for older adult breast cancer survivors.


CONCLUSIONS
Older adult breast cancer survivors should be assessed for a wide variety of symptoms if clinicians hope to identify and understand intersymptom relationships. Such assessment would enable more comprehensive symptom management.
John A Hartford Building Academic Geriatric Capacity scholar, University of Wisconsin-Madison, USA. raroiland@wisc.edu
Rachel A
RA
Roiland
Susan M
SM
Heidrich
D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D001943:Breast Neoplasms / Q000150:complications*; D016000:Cluster Analysis; D059026:Diagnostic Self Evaluation; D004522:Educational Status; D005163:Factor Analysis, Statistical; D005260:Female; D006801:Humans; D008487:Medical History Taking; D015399:Nursing Research; D011788:Quality of Life; D057566:Self Report; D017741:Survivors / Q000523:psychology*