Microwave-assisted benzyl-transfer reactions of commercially available 2-benzyloxy-1-methylpyridinium triflate.
Benzylation of alcohols and other substrates under thermal conditions translates smoothly from conventional heating into MW-assisted organic synthesis (MAOS). Reactions times are decreased from hours to minutes while good to excellent yields are maintained. MW heating should be considered for benzylation of high-value substrates using the title reagent.
Department of Chemistry and Biochemistry, Florida State University, Tallahassee, Florida, USA.
Teng-wei
TW
Wang
Tanit
T
Intaranukulkit
Michael R
MR
Rosana
Rimantas
R
Slegeris
Janet
J
Simon
Gregory B
GB
Dudley
D000438:Alcohols / Q000737:chemistry; D001593:Benzyl Compounds / Q000737:chemistry*; D002264:Carboxylic Acids / Q000737:chemistry; D004987:Ethers / Q000138:chemical synthesis* / Q000737:chemistry; D008698:Mesylates / Q000737:chemistry*; D008872:Microwaves; D015394:Molecular Structure; D011726:Pyridinium Compounds / Q000737:chemistry*
C525419:2-benzyloxy-1-methylpyridinium triflate; D000438:Alcohols; D001593:Benzyl Compounds; D002264:Carboxylic Acids; D004987:Ethers; D008698:Mesylates; D011726:Pyridinium Compounds