New approaches to the inhibition of replication of viral pathogens.
This meeting was a special symposium sponsored by the American Society for Biochemistry and Molecular Biology. The conference was held in Gangzhou, China on 24-26 July 2011 and shared a venue with the Society of Chinese Bioscientists in America Thirteenth International Symposium. Over 150 participants from the Americas, Europe, Asia and Australia attended the meeting. This article focuses on two areas of research in which there have been exciting developments that have application to the development of antivirals: the regulation of host and viral mRNA by RNAi and NF-κB regulation of viral gene expression.
Division of Pharmacology and Toxicology, UMKC-School of Pharmacy, 2464 Charlotte Street, Kansas City, MO 64108, USA. kumaran@umkc.edu
Anil
A
Kumar
Peter S
PS
Silverstein
D004261:DNA Replication / Q000187:drug effects*; D015967:Gene Expression Regulation, Viral / Q000187:drug effects; D006801:Humans; D035683:MicroRNAs / Q000494:pharmacology*; D008967:Molecular Biology / Q000379:methods*; D016328:NF-kappa B / Q000037:antagonists & inhibitors / Q000235:genetics / Q000378:metabolism*; D034622:RNA Interference; D012367:RNA, Viral / Q000037:antagonists & inhibitors; D015398:Signal Transduction; D014773:Virology / Q000379:methods*; D014777:Virus Diseases / Q000188:drug therapy / Q000821:virology; D014780:Viruses / Q000187:drug effects / Q000254:growth & development
D035683:MicroRNAs; D016328:NF-kappa B; D012367:RNA, Viral