Driving with no brakes: molecular pathophysiology of Kv7 potassium channels.
Kv7 potassium channels regulate excitability in neuronal, sensory, and muscular cells. Here, we describe their molecular architecture, physiological roles, and involvement in genetically determined channelopathies highlighting their relevance as targets for pharmacological treatment of several human disorders.
Department of Health Science, University of Molise, Campobasso, Italy.
Maria Virginia
MV
Soldovieri
Francesco
F
Miceli
Maurizio
M
Taglialatela
D000818:Animals; D006801:Humans; D051656:KCNQ Potassium Channels / Q000235:genetics* / Q000378:metabolism*; D057089:Pathology, Molecular
D051656:KCNQ Potassium Channels