Mode of delivery influences the regression of abnormal cervical cytology.
OBJECTIVE
The purpose was to investigate the influence of delivery mode on the postpartum regression of abnormal cervical cytology.


METHODS
A retrospective review was conducted of 64 pregnant women with abnormal cervical cytology at Yonsei University Health System in Korea between 2001 and 2008. A Papanicolaou smear and pathological data were categorized into three groups by cervical intraepithelial neoplasia classification. Postpartum evaluation was taken 3-6 months after delivery. The regression rates of cervical cytologic findings were compared between the vaginal delivery group and Cesarean section group. p < 0.05 was considered significant.


RESULTS
Of the 64 women, 45 (70.3%) were delivered vaginally and 19 (29.7%) by cesarean section. No significant difference was found between the two groups with respect to age, gestational age, parity, smoking, and HPV (human papilloma virus) screening. Postpartum regression was shown in 39 (92.9%) women who delivered vaginally and in 12 (63.2%) women who underwent cesarean section (p = 0.016). In the cesarean section group, 1 patient had progressed from CIN2 to microinvasive cancer and 2 patients from carcinoma in situ to invasive cancer.


CONCLUSIONS
The rate of spontaneous regression of antepartum abnormal cervical cytology was higher after vaginal delivery.
Department of Obstetrics and Gynecology, Yonsei University College of Medicine, Seoul, Korea.
Sue Min
SM
Chung
Ga Hyun
GH
Son
Eun Ji
EJ
Nam
Young Han
YH
Kim
Young Tae
YT
Kim
Yong Won
YW
Park
Ja Young
JY
Kwon
D000328:Adult; D002585:Cesarean Section; D036861:Delivery, Obstetric / Q000379:methods*; D005260:Female; D006801:Humans; D060787:Neoplasm Grading; D009365:Neoplasm Regression, Spontaneous / Q000473:pathology*; D065006:Papanicolaou Test; D049590:Postpartum Period; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic; D012189:Retrospective Studies; D002583:Uterine Cervical Neoplasms / Q000473:pathology*; D014626:Vaginal Smears; D002578:Uterine Cervical Dysplasia / Q000473:pathology*