MINOS is plus: a Mitofilin complex for mitochondrial membrane contacts.
Cristae junctions mark the boundaries of respiratory compartments in the inner mitochondrial membrane. In this issue of Developmental Cell, von der Malsburg et al. (2011) identify a complex, MINOS, that organizes cristae junctions. Mitofilin/Fcj1, the central component of the MINOS complex, also connects the inner membrane to outer membrane protein import machinery.
Cell Biology, University of Kaiserslautern, Erwin-Schrödinger-Strasse 13, 67663 Kaiserslautern, Germany. hannes.herrmann@biologie.uni-kl.de
Johannes M
JM
Herrmann