Hyperacute rejection from a donor who died of carbamate intoxication--a case report.
Acute carbamate intoxication can cause cardiac manifestations. We present the case of a 53-year-old man who had been a heavy smoker, admitted to our hospital for recent anterior wall myocardial infarction complicated with congestive heart failure. Percutaneous transluminal coronary angioplasty with stent implantation, coronary artery bypass graft, and mitral annuloplasty were performed, but refractory heart failure and ventricular arrhythmia were still noted. He received orthotropic heart transplantation 7 days later. The donor was a 50-year-old man who had died of brain death due to carbamate intoxication, and the crossmatch before transplantation was negative. The recipient died 24 hours after the operation due to acute left ventricular dysfunction. This report reviews the cardiac manifestations of acute carbamate intoxication and the possibility of heart transplantations from donors who died of carbamate intoxication.
Division of Cardiology, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taipei, Taiwan.
Yi-Hsin
YH
Chan
Kuo-Ping
KP
Liew
Charles Chien-Feng
CC
Sun
Chuen
C
Hsueh
Bing-Chin
BC
Li
Feng-Chun
FC
Tsai
Ja-Liang
JL
Lin
Pao-Hsien
PH
Chu
D000208:Acute Disease; D002219:Carbamates / Q000506:poisoning*; D017809:Fatal Outcome; D006084:Graft Rejection / Q000209:etiology*; D006321:Heart / Q000187:drug effects; D016027:Heart Transplantation / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D014019:Tissue Donors
D002219:Carbamates