Does acceptance and relationship focused behavior therapy contribute to bupropion outcomes? A randomized controlled trial of functional analytic psychotherapy and acceptance and commitment therapy for smoking cessation.
This study evaluated a treatment combining bupropion with a novel acceptance and relationship focused behavioral intervention based on the acceptance and relationship context (ARC) model. Three hundred and three smokers from a community sample were randomly assigned to bupropion, a widely used smoking cessation medication, or bupropion plus functional analytic psychotherapy (FAP) and acceptance and commitment therapy (ACT). Objective measures of smoking outcomes and self-report measures of acceptance and relationship processes were taken at pretreatment, posttreatment, 6-month, and 1-year follow-up. The combined treatment was significantly better than bupropion alone at 1-year follow-up with 7-day point prevalence quit rates of 31.6% in the combined condition versus 17.5% in the medication-alone condition. Acceptance and the therapeutic relationship at posttreatment statistically mediated 12-month outcomes. Bupropion outcomes were enhanced with an acceptance and relationship focused behavioral treatment.
Department of Veterans Affairs, Center for Health Care Evaluation, 795 Willow Rd., Menlo Park, CA 94025, USA. Elizabeth.Gifford@va.gov
Elizabeth V
EV
Gifford
Barbara S
BS
Kohlenberg
Steven C
SC
Hayes
Heather M
HM
Pierson
Melissa P
MP
Piasecki
David O
DO
Antonuccio
Kathleen M
KM
Palm
D000328:Adult; D001521:Behavior Therapy / Q000379:methods*; D016642:Bupropion / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D018765:Dopamine Uptake Inhibitors / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009042:Motivation; D012907:Smoking / Q000188:drug therapy / Q000523:psychology / Q000628:therapy*; D016540:Smoking Cessation / Q000379:methods* / Q000523:psychology; D061485:Tobacco Use Cessation Devices; D016896:Treatment Outcome
D018765:Dopamine Uptake Inhibitors; D016642:Bupropion