Myxoid liposarcoma of the ankle: a case report.
Myxoid liposarcoma occurs predominantly in the deep soft tissues of the extremities, and tends to metastasize to a wide range of soft tissue or bone locations. We report a case of myxoid liposarcoma arising in the ankle of a 19-year-old man. A diagnosis of myxoid liposarcoma was made by open biopsy, and a wide resection requiring plastic surgical reconstruction was performed. Cytogenetic analysis of the resected tumor exhibited a reciprocal translocation t(12;16)(q13;p11) as the sole anomaly, which is found in more than 90% of myxoid liposarcoma cases. The patient had no evidence of local recurrence or metastasis within 7 years of follow-up. Although myxoid liposarcoma is rare in the ankle, it should be considered in the differential diagnosis of a painless soft tissue mass in this region.
Department of Orthopaedic Surgery, Faculty of Medicine, Fukuoka University, Jonan-ku, Fukuoka, Japan. jnishio@cis.fukuoka-u.ac.jp
Jun
J
Nishio
Teruto
T
Isayama
Ichiro
I
Yoshimura
Hiroyuki
H
Ohjimi
Hiroshi
H
Iwasaki
Masatoshi
M
Naito
D000842:Ankle / Q000601:surgery*; D006801:Humans; D018208:Liposarcoma, Myxoid / Q000473:pathology* / Q000601:surgery*; D008297:Male; D012983:Soft Tissue Neoplasms / Q000473:pathology* / Q000601:surgery*; D055815:Young Adult