[Evaluation of two arterial closure devices, Angioseal and Perclose, in coronary catheter interventions].
OBJECTIVE
To assess the efficacy and safety of two arterial closure devices, Angioseal and Perclose, in patients undergoing coronary angiography and invasive interventions.


METHODS
From January 2001 to April 2011, 997 inpatients underwent coronary angiography and interventions with arterial closure using Perclose (486 cases) or Angioseal (511 cases). The time to ambulation and hemostasis, major vascular complications and deployment success rate with the two devices were compared.


RESULTS
The time to hemostasis was significantly shorter in Angioseal group than in Perclose group (3∓0.9 min vs 10.8∓4.8 min, P<0.001), but the time to ambulation was comparable between the two groups (6.4∓1.2 h vs 6.3∓0.7 h, P>0.05). The incidences of vascular complications showed no significant differences between the two groups (4.5% vs 3.7%, P>0.05), and none of the cases in either group developed femoral artery thrombosis or low limb embolism following the procedures. The deployment success rate was comparable between the two groups (97.8% vss 98.6%, P>0.05), and deployment failure was associated mainly with mishandling and design defect of the devices.


CONCLUSIONS
Angioseal and Perclose are both effective and safe for arterial closure with reduced hemostasis and ambulation time and low incidences of vascular complications. Angioseal appears to have better performance than Perclose in shortening the hemostasis time and is easier to handle.
Department of Cardiology, Southern Medical University, Guangzhou, China. zzj2001911@126.com
Zhong-jiang
ZJ
Zhou
Kai
K
Cui
Shi-ping
SP
Cao
Zheng
Z
Huang
Zhi-gang
ZG
Guo
Jian-cheng
JC
Xiu
Yu-qing
YQ
Hou
D000368:Aged; D015906:Angioplasty, Balloon, Coronary / Q000009:adverse effects*; D002681:China; D017023:Coronary Angiography / Q000009:adverse effects*; D003327:Coronary Disease / Q000000981:diagnostic imaging / Q000628:therapy*; D005260:Female; D005263:Femoral Artery / Q000601:surgery; D006489:Hemostatic Techniques / Q000295:instrumentation*; D006801:Humans; D008297:Male; D008875:Middle Aged; D016491:Peripheral Vascular Diseases / Q000209:etiology; D012189:Retrospective Studies