Bilateral multicystic parotid masses in primary Sjögren syndrome.
We report the case of a 48-year-old woman who presented with bilateral parotid gland enlargement as the initial manifestation of primary Sjögren syndrome. Magnetic resonance imaging demonstrated multiple areas of low-intensity signal mixed with foci of high-intensity signal, a finding suggestive of Sjögren syndrome. Autoimmune blood tests for Sjögren syndrome were positive, and a sublabial biopsy confirmed the diagnosis. Investigations for other conditions, including human immunodeficiency virus infection, were negative. After 5 years of follow-up, the parotid swellings remained essentially unchanged. We discuss the etiology of multicystic parotid gland pathology, its involvement in Sjögren syndrome, and the risk of lymphoma.
Department of Otolaryngology, Royal Blackburn Hospital, Blackburn, UK. alextoh@doctors.org.uk
Alex S
AS
Toh
Stephen J
SJ
Broomfield
Lee-Suan
LS
Teh
Muhammad B
MB
Aslam
Gavin
G
Duncan
Pradeep
P
Morar
D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010307:Parotid Neoplasms / Q000209:etiology* / Q000473:pathology*; D012859:Sjogren's Syndrome / Q000150:complications / Q000175:diagnosis* / Q000276:immunology / Q000473:pathology