Comparative effectiveness of dried-plasma hepatitis B virus viral load (VL) testing in three different VL commercial platforms using ViveST for sample collection.
Ninety-six samples from hepatitis B virus (HBV)-infected individuals were used to compare ViveST samples to frozen samples in COBAS TaqMan, RealArt, and VERSANT. Correlation (r) between ViveST samples and frozen samples was 0.99 in all three platforms. Correlations among tests using frozen samples were 0.96 for COBAS and RealArt, 0.94 for COBAS and VERSANT, and 0.97 for VERSANT and RealArt. The results indicate that ViveST may be useful in clinical practice. Different HBV-VL platforms correlated well with one another.
Retrovirology Laboratory, Federal University of Sao Paulo, Sao Paulo, Brazil.
Michelle
M
Zanoni
Leila B
LB
Giron
Cintia
C
Vilhena
Maria Cecilia
MC
Sucupira
Robert M
RM
Lloyd
Ricardo Sobhie
RS
Diaz
D003890:Desiccation / Q000379:methods*; D005615:Freezing; D006509:Hepatitis B / Q000175:diagnosis* / Q000821:virology*; D006515:Hepatitis B virus / Q000235:genetics / Q000302:isolation & purification*; D006801:Humans; D010949:Plasma / Q000821:virology*; D013048:Specimen Handling / Q000379:methods*; D019562:Viral Load / Q000379:methods*