Palladium-catalyzed carbonylative reaction of 1-(2,2-dibromovinyl)-2-alkenylbenzene and carbon monoxide, with phenol or alcohol.
A palladium-catalyzed carbonylative reaction of 1-(2,2-dibromovinyl)-2-alkenylbenzene and carbon monoxide, with phenol or alcohol, is reported, which affords 1-methylene-1H-indene-2-carboxylates in moderate to good yields. This cascade process, which includes carbonylation and Heck reaction, proceeds smoothly with good functional group tolerance and high selectivity.
Department of Chemistry, Fudan University, 220 Handan Road, Shanghai 200433, China.
Shengqing
S
Ye
Jie
J
Wu