Iatrogenic skin injury in hospitalized patients.
Iatrogenic skin injuries in hospitalized patients range from drug-related complications to those related to procedures. Common drug complications include drug reaction with eosinophilia and systemic symptoms (DRESS), linear immunoglobulin (Ig) A bullous dermatosis, Stevens-Johnson syndrome/toxic epidermal necrolysis, and acute generalized exanthematous pustulosis. Contact dermatitis can result from surgical preparations of chlorhexidine and povidone-iodine, medical adhesives, topical postsurgical ointments, most commonly neomycin and bacitracin, and internal prostheses, including coronary stents, pacemakers, and metal joints. Complications arising from procedures include thrombosis caused by placement of peripherally inserted central catheters, pyoderma gangrenosum from sites of dermal trauma, and anetoderma of prematurity from cutaneous monitoring devices in neonates. Calcinosis cutis and decubitus ulcers are also hospital problems.
Department of Dermatology, Massachusetts General Hospital, 50 Staniford St, Ste 200, Boston, MA 02114, USA.
Carol E
CE
Cheng
Daniela
D
Kroshinsky
D056150:Acute Generalized Exanthematous Pustulosis / Q000139:chemically induced; D057088:Anetoderma / Q000209:etiology; D002114:Calcinosis / Q000139:chemically induced; D003877:Dermatitis, Contact / Q000209:etiology; D004342:Drug Hypersensitivity / Q000209:etiology; D006760:Hospitalization; D006801:Humans; D007049:Iatrogenic Disease; D008047:Lip Diseases / Q000139:chemically induced; D003668:Pressure Ulcer / Q000209:etiology; D017511:Pyoderma Gangrenosum / Q000139:chemically induced; D012867:Skin / Q000293:injuries*; D012871:Skin Diseases / Q000139:chemically induced / Q000209:etiology*; D012872:Skin Diseases, Vesiculobullous / Q000139:chemically induced; D013262:Stevens-Johnson Syndrome / Q000209:etiology