[Chemical constituents of Excoecaria acerifclia].
OBJECTIVE
To study the chemical constituents of Excoecaria acerifclia.


METHODS
Column chromatography on Silica gel and Sephadex LH-20 were applied for isolation and purification of the constituents. The structures were elucidated on the basis of spectrascopic analysis, chemical evidences and by comparison with the data reported in the literature.


RESULTS
From the crude EtOAc fraction of Excoecaria acerifclia F. Didr, 14 compounds were isolated and identified as 7,8-trans-4,5,9-trihydroxy-3,3',9'-trimethoxy-7-O-5',8-O-4'-neolignan (1), 7,8-trans 4,5,9,9'-tetrahydroxy-3,3'-dimethoxy-7-O-5',8-O-4'-neolignan (2), malloapelin C (3), sy-ringaresinol (4), 2alpha,3beta,24-trihydroxy-12-ursen-28-oic acid (5), 11-hydroxy-3-oxo-12-ursen-28-oic acid (6), 6-hydroxy-20 (29)-lupen-3-one (7), isolupenyl acetate (8), kaempferol (9), quercetin (10), apigenin (11), catechin (12), kamepferol-3-O-beta-D-galactopyranoside (13), and catechin (6-->8) catechin (14).


CONCLUSIONS
Compound 1 was new, the remained compounds were isolated and identified from E. acerifclia for the first time. Among them, compounds 5-8 are triterpenoids, while the other compounds are phenylpropanoids.
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, Yunnan, P. R. China.
Jiang
J
Hu
Lanchun
L
Zhang
Qinshi
Q
Zhao
D002845:Chromatography; D004365:Drugs, Chinese Herbal / Q000737:chemistry; D019665:Euphorbiaceae / Q000737:chemistry*; D009930:Organic Chemicals / Q000032:analysis*
D004365:Drugs, Chinese Herbal; D009930:Organic Chemicals