Fine needle aspiration biopsy of intraparotid spindle cell lipoma: a case report.
Intraparotid spindle cell lipoma (SCL) of the salivary gland is a rare entity. Review of the literature revealed only two previous reports describing its cytological features. We report a case of a 44-year-old man who complained for a slowly growing, asymptomatic mass in the left parotid gland that since 12 months. Fine needle aspiration biopsy (FNAB) showed a loose collections of bland-appearing spindle cells in a myxoid background admixed with capillary fragments and some mature fat cells suggesting a diagnosis of SCL. A cytological diagnosis of mesenchymal myxoid spindle cell tumor with lipomatous differentiation, possibly an intraparotideal SCL was performed. Histological examination of the mass and the positive immunostaining for CD34 and negativity for S-100, CK-cocktail, and actin confirmed the diagnosis of SCL. The diagnosis of intraparotid SCL can be made by examining cytologic material containing mature fat with bland spindle cells in a myxoid background. FNAB diagnosis on SCL also allows to rule out other primary salivary gland tumors that may be clinically and instrumentally indistinguishable and thereby permits an appropriate surgical procedure to ensue.
Department of Pathologic Anatomy and Oncology, A.O.U. San Giovanni di Dio e Ruggi d'Aragona via S. Leonardo, Salerno, Italy. ada66@inwind.it
Antonio
A
D'Antonio
Carlo
C
Baldi
Domenico
D
Memoli
Alessia
A
Caleo
Rosa
R
Rosamilio
Pio
P
Zeppa
D000199:Actins / Q000032:analysis; D017667:Adipocytes / Q000473:pathology; D000328:Adult; D018952:Antigens, CD34 / Q000032:analysis; D044963:Biopsy, Fine-Needle; D006801:Humans; D008067:Lipoma / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000473:pathology*; D008297:Male; D010306:Parotid Gland / Q000000981:diagnostic imaging; D010307:Parotid Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000473:pathology*; D009418:S100 Proteins / Q000032:analysis; D014463:Ultrasonography
D000199:Actins; D018952:Antigens, CD34; D009418:S100 Proteins