title: Annular elastolytic giant cell granuloma--case report.
abstract: Annular elastolytic giant cell granuloma is a rare granulomatous skin disease characterized histologically by phagocytosis of elastic fibers by multinucleated giant cells and clinically by annular patches with elevated borders and atrophic centers found mainly on sun-exposed skin. The pathogenesis of the disease is controversial. We report the case of a 44-year-old woman with classical clinical and histological findings of the disease whose condition improved when hydroxychloroquine was administered over a four-week period.
authors: Serviço de Dermatologia, Universidade Federal do Pará, Belém, PA, Brasil.
authors: Rossana Ruth da Veiga
authors: RR
authors: Gonçalves
authors: Mario Fernando Ribeiro de
authors: MF
authors: Miranda
authors: Fernanda de Oliveira
authors: Fde O
authors: Viana
authors: Luíza Helena dos Santos
authors: LH
authors: Cavaleiro
authors: Diana Mendes da
authors: DM
authors: Fonseca
mesh_terms: D000328:Adult; D018501:Antirheumatic Agents / Q000627:therapeutic use; D004547:Elastic Tissue / Q000473:pathology; D005260:Female; D005542:Forearm; D006101:Granuloma, Giant Cell / Q000188:drug therapy / Q000473:pathology*; D006801:Humans; D006886:Hydroxychloroquine / Q000627:therapeutic use; D012871:Skin Diseases / Q000188:drug therapy / Q000473:pathology*
chemical_list: D018501:Antirheumatic Agents; D006886:Hydroxychloroquine