title: Indications and practice with androgen deprivation therapy.
abstract: The Cancer of the Prostate Strategic Urological Research Endeavor (CaPSURE) is an ongoing longitudinal observational study of current trends in prostate cancer staging and treatment across a spectrum of different treatment facilities in the United States. To date, the study has documented 2 principal findings: (a) a large variation exists in the treatment choices applied to similar patient presentations across the range of facility type, size, and geographic location in the United States; and (b) although it does not seem to make much difference in mortality outcomes which approach--hormonal therapy, radiotherapy, or surgery--is applied to men at low or intermediate risk, a survival benefit exists with surgery for men at high risk.
authors: Division of Urologic Surgery, Department of Surgery, Duke University Medical Center, Durham, North Carolina, USA.
authors: Judd W
authors: JW
authors: Moul
authors: Adam S
authors: AS
authors: Kibel
authors: Mack
authors: M
authors: Roach
authors: Robert
authors: R
authors: Dreicer
mesh_terms: D000726:Androgen Antagonists / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D011471:Prostatic Neoplasms / Q000188:drug therapy*
chemical_list: D000726:Androgen Antagonists