title: [Studies of mutagenic activity of positively charged alkyl glycerolipids in Ames test].
abstract: Mutagenic activity of non-phosphorous cationic alkyl glycerolipid rac-N-{4-[(2-Methoxy-3-octadecyloxy)propyl]oxycarbonylbutyl}-N,N-dimethyl-N-(2-hydroxyethyl) ammonium iodide was evaluated. According performed Ames assay results indicated on non-mutagenic properties tested compound. Resulting data open the possibility to carry out biological study in vivo for class of ether cationic glycerolipids and further applications as a potential agent of anticancer therapy.
authors: S G
authors: SG
authors: Romanova
authors: G A
authors: GA
authors: Belitskiĭ
authors: I A
authors: IA
authors: Khitrovo
authors: G A
authors: GA
authors: Serebrennikova
authors: A A
authors: AA
authors: Shtil'
mesh_terms: D000970:Antineoplastic Agents / Q000737:chemistry / Q000494:pharmacology; D004354:Drug Screening Assays, Antitumor; D006017:Glycolipids / Q000737:chemistry / Q000494:pharmacology; D016296:Mutagenesis / Q000187:drug effects*; D012486:Salmonella typhimurium / Q000235:genetics* / Q000254:growth & development / Q000378:metabolism
chemical_list: D000970:Antineoplastic Agents; D006017:Glycolipids