title: Remineralization of primary tooth enamel from individuals with Down syndrome.
abstract: OBJECTIVE
  The purpose of this study was to clarify the characteristics of primary tooth enamel of Down syndrome patients (DSPs). We examined 9 primary teeth of Down syndrome children and 11 primary teeth of normally developed children to investigate the remineralization processes  of enamel by transverse microradiography and X ray micro analyzer (XMA).
  
  
  METHODS
  Mineral loss, lesion depth, maximum mineral value, minimum mineral value, depth of maximum mineral value, and depth of minimum mineral value were used to analyze transverse microradiography  (TMR). In addition, we calculated the percentage of enamel remineralization.
  
  
  RESULTS
  All the parameters in the 2 groups showed marked recovery. The results indicated that the Down syndrome group was significantly remineralized the same way as the control group. According  to the comparison of mineral content distribution by XMA, the content distribution of magnesium was different between the 2 groups.
  
  
  CONCLUSIONS
  While recovery through remineralization of primary teeth was similar between Down syndrome children and normally developed children, the  mechanism of remineralization process may be different between the 2 groups; consequently, magnesium may be considered as one of the factors affecting recovery.
authors: School of Dentistry, Aichi-Gakuin university, Nagoya, Japan. okataku@dpc.aichi-gakuin.ac.jp
authors: Takuma
authors: T
authors: Okamoto
authors: Munenori
authors: M
authors: Shibata
authors: Shinji
authors: S
authors: Tsuboi
authors: Haruo
authors: H
authors: Nakagaki
authors: Osamu
authors: O
authors: Fukuta
authors: Yoshitaka
authors: Y
authors: Kusabe
authors: Junko
authors: J
authors: Inukai
mesh_terms: D002648:Child; D003743:Dental Enamel / Q000000981:diagnostic imaging / Q000473:pathology*; D004314:Down Syndrome / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D008852:Microradiography; D018709:Statistics, Nonparametric; D017001:Tooth Demineralization / Q000000981:diagnostic imaging / Q000473:pathology*; D014089:Tooth Remineralization; D014094:Tooth, Deciduous