title: Bispectral index monitoring in the management of sedation in an intensive care unit patient with locked-in syndrome.
abstract: Locked-in syndrome is an extremely rare neurological state caused by injury of the ventral pons. The syndrome is characterized by quadriplegia and anarthria with concomitant preservation of cortical function. When a reversible underlying pathological abnormality is identified and managed aggressively, meaningful recovery is possible. Because patients retain consciousness throughout their illness, a dependable method for titrating sedation may improve their quality of life. The case presented suggests that bispectral index monitoring may be a cost-effective and reliable method for managing sedation in patients with locked-in syndrome.
authors: Harvard Medical School, Boston, Massachusetts, USA. squraishi@partners.org
authors: Sadeq A
authors: SA
authors: Quraishi
authors: Sandralee A
authors: SA
authors: Blosser
authors: Robert A
authors: RA
authors: Cherry
mesh_terms: D016292:Procedural Sedation; D056805:Consciousness Monitors; D006801:Humans; D007362:Intensive Care Units; D011782:Quadriplegia; D011788:Quality of Life