title: Catalytic hydroacylation as an approach to homoaldol products.
abstract: A method has been developed for the intermolecular hydroacylation of homoallyl alcohols with salicylaldehydes to furnish homoaldol products in 50-98% yields. The method also applies to the hydroacylation of 2-hydroxystyrenes. This work highlights the use of hydroacylation as a unified approach to both aldol and homoaldol products.
authors: Department of Chemistry, University of Toronto, 80 St. George Street, Toronto, Ontario M5S 3H6, Canada.
authors: Stephen K
authors: SK
authors: Murphy
authors: David A
authors: DA
authors: Petrone
authors: Matthew M
authors: MM
authors: Coulter
authors: Vy M
authors: VM
authors: Dong
mesh_terms: D000438:Alcohols / Q000138:chemical synthesis / Q000737:chemistry*; D000447:Aldehydes / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D013343:Styrenes / Q000737:chemistry
chemical_list: D000438:Alcohols; D000447:Aldehydes; D013343:Styrenes; C013243:salicylaldehyde; C116609:3-hydroxybutanal