title: Cutaneous Ewing sarcoma: report of 2 cases and literature review of presentation, treatment, and outcome of 76 other reported cases.
abstract: Cutaneous Ewing sarcoma is a rare variant that has been poorly characterized and has no standard therapy. We report 2 patients with cutaneous Ewing sarcoma and review 76 other cases reported in the literature for demographics, presentation, treatment, and outcome. Only 2 patients presented with metastatic disease, and only 8 patients developed metastatic disease. Ninety-one percent of all patients are alive despite wide variations in treatment regimens. On the basis of this summary, treatment consisting of local control with surgery and/or radiation and abbreviated chemotherapy is proposed as a treatment option for this less aggressive Ewing sarcoma.
authors: Department of Pediatrics, Lehigh Valley Hospital Health Network, University of South Florida College of Medicine, Bethlehem, PA, USA. Anderson.Collier@lvh.com
authors: Anderson B
authors: AB
authors: Collier
authors: Lesley
authors: L
authors: Simpson
authors: Philip
authors: P
authors: Monteleone
mesh_terms: D000293:Adolescent; D059248:Chemoradiotherapy; D002648:Child; D005260:Female; D006801:Humans; D012074:Remission Induction; D012512:Sarcoma, Ewing / Q000473:pathology / Q000601:surgery / Q000628:therapy; D012878:Skin Neoplasms / Q000473:pathology / Q000601:surgery / Q000628:therapy; D016896:Treatment Outcome