title: Sleep-wake patterns of school-age children and adolescents before diagnosis and during induction chemotherapy for acute lymphocytic leukemia.
abstract: Sleep disturbances are commonly reported by children receiving chemotherapy for leukemia. Sleep patterns before diagnosis and during induction chemotherapy were evaluated in 38 children (7 to 18 years old). Child Sleep Assessment (CSA) was used to evaluate sleep patterns prior to diagnosis. Sleep diaries and actigraphy were used during chemotherapy. Adolescents went to bed later and awakened later than school-age children before diagnosis and during chemotherapy. During chemotherapy, children averaged 60 minutes of nighttime wake time. The early recognition of sleep problems associated with disease, treatment, and age is important for school-age children and adolescents with leukemia.
authors: University of Washington, Department of Family and Child Nursing, Seattle, WA, USA. walkeraj@uw.edu
authors: Amy J
authors: AJ
authors: Walker
authors: Yupaporn
authors: Y
authors: Pongsing
authors: Lillian
authors: L
authors: Nail
authors: Nisreen
authors: N
authors: Pedhiwala
authors: Michael
authors: M
authors: Leo
authors: Joanne
authors: J
authors: Price
authors: Kathryn
authors: K
authors: Lee
authors: Vivian
authors: V
authors: Gedaly-Duff
mesh_terms: D000293:Adolescent; D000294:Adolescent Behavior / Q000187:drug effects; D002648:Child; D002652:Child Behavior / Q000187:drug effects; D005221:Fatigue / Q000453:epidemiology* / Q000209:etiology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D060828:Induction Chemotherapy; D008137:Longitudinal Studies; D008297:Male; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000175:diagnosis / Q000188:drug therapy* / Q000523:psychology; D011446:Prospective Studies; D018570:Risk Assessment; D012894:Sleep Stages / Q000187:drug effects; D012893:Sleep Wake Disorders / Q000453:epidemiology / Q000209:etiology* / Q000503:physiopathology; D013997:Time Factors