title: [Claude Bernard pioneer of experimental medicine and clinical research].
abstract: With the publication of l"Introduction à l'étude de la médecine expérimentale (Introduction to the Study of Experimental Medicine) in 1865, Claude Bernard opened up a new concept in experimental methodology. By stressing the essential link between clinical observation, exploration of the "internal medium", and animal studies, he established the founding principles of clinical research.
authors: l'Académie nationale de médecine. rene.mornex@chu-lyon.fr
authors: René
authors: R
authors: Mornex
mesh_terms: D000818:Animals; D035843:Biomedical Research / Q000266:history* / Q000379:methods; D003210:Concept Formation; D005602:France; D049672:History, 19th Century; D006801:Humans; D008962:Models, Theoretical; D011642:Publications / Q000266:history