title: Correlation-induced spectral changes in tissues.
abstract: We report experimental evidence of correlation-induced spectral changes in biological tissues. The overall spectral shift in our transmission measurements is to the red and the mean wavelength of the original spectrum is up 10% larger. These results indicate that the spectral changes due to elastic scattering are significant and likely to hinder all spectroscopic measurements based on the inelastic (i.e., emission and absorption) interaction between light and tissues. Thus, simultaneous morphology and spectral measurements are required for accurate measurements spectroscopic information.
authors: Quantitative Light Imaging Laboratory, Department of Electrical and Computer Engineering, Beckman Institute for Advanced Science & Technology, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801 USA.
authors: Ruoyu
authors: R
authors: Zhu
authors: Shamira
authors: S
authors: Sridharan
authors: Krishnarao
authors: K
authors: Tangella
authors: Andre
authors: A
authors: Balla
authors: Gabriel
authors: G
authors: Popescu
mesh_terms: D001706:Biopsy; D006454:Hemoglobins / Q000737:chemistry; D006801:Humans; D055620:Optical Phenomena; D010108:Oxyhemoglobins / Q000737:chemistry; D012542:Scattering, Radiation; D013057:Spectrum Analysis / Q000379:methods* / Q000706:statistics & numerical data; D013059:Spectrum Analysis, Raman; D014018:Tissue Distribution
chemical_list: D006454:Hemoglobins; D010108:Oxyhemoglobins; C100003:deoxyhemoglobin