title: Lemierre syndrome in a 22-month-old due to Streptococcus pyogenes: a case report.
abstract: We report a case of Lemierre syndrome secondary to Streptococcus pyogenes in a 22-month-old girl. This case report and literature review took place at a pediatric intensive care unit at a freestanding tertiary children's hospital. Diagnosis occurred after the discovery of left internal jugular thrombus and multiple metastatic infection sites including the right knee, kidneys, lungs, and brain. Lemierre syndrome can occur in young children secondary to S. pyogenes, and a classic presentation may not occur. A high index of suspicion is crucial to the diagnosis.
authors: Department of Anesthesiology and Critical Care Medicine, Nemours Children's Clinic-Wilmington, Alfred I. duPont Hospital for Children, Wilmington, DE 19803, USA. mfrizzol@nemours.org
authors: Meg A
authors: MA
authors: Frizzola
authors: James H
authors: JH
authors: Hertzog
mesh_terms: D000667:Ampicillin / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001170:Arthritis, Infectious / Q000188:drug therapy / Q000382:microbiology; D016470:Bacteremia / Q000188:drug therapy / Q000209:etiology / Q000382:microbiology; D002443:Ceftriaxone / Q000627:therapeutic use; D002675:Child, Preschool; D005260:Female; D005334:Fever / Q000209:etiology; D020022:Genetic Predisposition to Disease; D006579:Heterozygote; D006801:Humans; D007601:Jugular Veins / Q000382:microbiology; D057831:Lemierre Syndrome / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology / Q000382:microbiology*; D042965:Methylenetetrahydrofolate Reductase (NADPH2) / Q000235:genetics; D010019:Osteomyelitis / Q000209:etiology / Q000382:microbiology; D010612:Pharyngitis / Q000150:complications / Q000188:drug therapy / Q000382:microbiology; D013290:Streptococcal Infections / Q000188:drug therapy / Q000382:microbiology*; D013297:Streptococcus pyogenes / Q000302:isolation & purification*; D019851:Thrombophilia / Q000150:complications / Q000235:genetics
chemical_list: D000900:Anti-Bacterial Agents; D002443:Ceftriaxone; D000667:Ampicillin; D042965:Methylenetetrahydrofolate Reductase (NADPH2)