title: ROPGAPs of Arabidopsis limit susceptibility to powdery mildew.
abstract: The barley ROP GTPase HvRACB is a susceptibility factor of barley to powdery mildew caused by the biotrophic fungus Blumeria graminis f.sp. hordei (Bgh). In a recent publication, we reported about a MICROTUBULE-ASSOCIATED ROP GTPASE-ACTIVATING PROTEIN 1 (HvMAGAP1) of barley. Transient-induced gene silencing or overexpression of HvMAGAP1 resulted in enhanced or reduced susceptibility to Bgh, respectively, indicating a possible HvRACB-antagonistic function of HvMAGAP1 in interaction with Bgh. HvMAGAP1 also influences the polarity of cortical microtubules in interaction with Bgh. In AtROPGAP1 and AtROPGAP4, Arabidopsis homologs of HvMAGAP1, knock-out T-DNA insertions enhanced susceptibility of Arabidopsis to the virulent powdery mildew fungus Erysiphe cruciferarum, indicating functions of ROPGAPs in pathogen interaction of monocots and dicots. Here we discuss the role of AtROPGAP1 and AtROPGAP4 in Arabidopsis pathogenesis of powdery mildew in some more detail.
authors: Lehrstuhl für Phytopathologie, Technische Universität München, Freising-Weihenstephan, Germany.
authors: Christina
authors: C
authors: Huesmann
authors: Caroline
authors: C
authors: Hoefle
authors: Ralph
authors: R
authors: Hückelhoven
mesh_terms: D017360:Arabidopsis / Q000235:genetics* / Q000378:metabolism / Q000382:microbiology; D029681:Arabidopsis Proteins / Q000235:genetics / Q000378:metabolism*; D001203:Ascomycota / Q000472:pathogenicity*; D004269:DNA, Bacterial; D004198:Disease Susceptibility; D018506:Gene Expression Regulation, Plant; D020868:Gene Silencing; D016254:Mutagenesis, Insertional; D010935:Plant Diseases / Q000235:genetics*; D020741:rho GTP-Binding Proteins / Q000235:genetics / Q000378:metabolism*
chemical_list: D029681:Arabidopsis Proteins; D004269:DNA, Bacterial; C036483:T-DNA; C459444:RopGAP4 protein, Arabidopsis; D020741:rho GTP-Binding Proteins