title: [The progress study of HDAC2 function in diseases].
abstract: HDAC2 is a histone acetyltransferase I, promotes the hormone and cytokine-dependent signal transduction. HDAC2 is unique marker for oral, prostate, ovarian, endometrial or gastric cancer, and related with muscle and heart related diseases, it plays an important role in embryonic development and neural function. As the precise target of drug development and drug intervention technology, HDAC2 has been proved to be an effective treatment. In this paper, the role of HDAC2 is summarized in health and related diseases.
authors: Guangxi University, NanNing 530004, China.
authors: Li-he
authors: LH
authors: Jiang
mesh_terms: D000818:Animals; D014408:Biomarkers, Tumor; D047108:Embryonic Development / Q000502:physiology*; D006331:Heart Diseases / Q000201:enzymology* / Q000503:physiopathology; D056464:Histone Deacetylase 2 / Q000502:physiology*; D006801:Humans; D008297:Male; D009062:Mouth Neoplasms / Q000201:enzymology; D009369:Neoplasms / Q000201:enzymology* / Q000503:physiopathology; D011471:Prostatic Neoplasms / Q000201:enzymology
chemical_list: D014408:Biomarkers, Tumor; D056464:Histone Deacetylase 2