title: [Primary evaluation of a mass screening program for colorectal tumor in China].
abstract: OBJECTIVE
  To evaluate a colorectal cancer screening program by tumor detection rate and discussing its application values.
  
  
  METHODS
  In total, 43 713 subjects were recruited in the screening program who were the registered people aged 40 - 74 in Xiacheng and Jiashan during year 2007 - 2009. The first screening involved questionnaire survey of colorectal cancer related risk factors and fecal occult blood test (FOBT), colonoscopy was performed when a positive result was observed in the first screening. If polyps were found during colonoscopy, biopsy and pathological diagnosis were carried out. The screening data were analyzed and the tumor detection rate was calculated according to age or sex.
  
  
  RESULTS
  6489 subjects (14.85%) belonged to the high risk group of colorectal cancer in the first screening, in which 4701 subjects finished complete colonoscopy. Finally, 569 colorectal neoplasm were diagnosed, the detection rate was 12.10% (95%CI: 11.17% - 13.04%). It included 52 colorectal cancer (1.11%, 95%CI: 0.81% - 1.41%), 183 advanced adenoma (3.89%, 95%CI: 3.34% - 4.45%), 334 non-advanced adenoma (7.10%, 95%CI: 6.37% - 7.84%). The highest detective rate was observed in male group that aged 70 - 74 (22.81%, 95%CI: 16.98% - 28.70%), the lowest detective rate was observed in female group aged 40 - 44 (2.49%, 95%CI: 0.79% - 4.20%).
  
  
  CONCLUSIONS
  The current colorectal cancer screening program in China works well, but the revision of the program is necessary.
authors: Cancer Institute, the Second Affiliated Hospital, Zhejiang University, School of Medicine (Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education, Key Laboratory of Molecular Biology in Medical Science, Zhejiang Province), Hangzhou 310009, China.
authors: Yan-Qin
authors: YQ
authors: Huang
authors: Shan-Rong
authors: SR
authors: Cai
authors: Su-Zhan
authors: SZ
authors: Zhang
authors: Qi-Long
authors: QL
authors: Li
authors: Xin-Yuan
authors: XY
authors: Ma
authors: Yu-Fang
authors: YF
authors: He
authors: Xiao-Hong
authors: XH
authors: Zhou
authors: Shu
authors: S
authors: Zheng
mesh_terms: D000328:Adult; D000368:Aged; D001706:Biopsy; D002681:China; D015179:Colorectal Neoplasms / Q000175:diagnosis / Q000517:prevention & control*; D005260:Female; D006801:Humans; D008297:Male; D008403:Mass Screening / Q000379:methods*; D008875:Middle Aged; D011795:Surveys and Questionnaires