title: [The clinical study of femtosecond lenticule extraction for myopia].
abstract: OBJECTIVE
  To evaluate the clinical efficacy, safety and predictability of femtosecond lenticule extraction (FLEx) for myopia.
  
  
  METHODS
  This is a prospective Clinical trial involved 10 cases (10 eyes). The patients aged from 18 years old to 53 years old, an average of (34 ± 11) years old. Femtosecond lenticule extraction (FLEx) was used to treat myopia from -4.88 DS to -9.25 DS, an average of (-6.94 ± 1.50) DS with cylinder from 0.50 DC to 3.0 µm DC an average of (1.28 ± 0.73)DC. Their corneal thickness were (527.10 ± 29.05) µm in an average. The patients were followed up for 6 to 10 months with visual acuity, manifest refraction, intraocular pressure, wavefront aberration, corneal topography and optical coherence tomography (OCT). SPSS software was used to analysis.
  
  
  RESULTS
  FLEx procedure was done well in every patients without any scanning problem. No infection happened to in the trial. The patients' UCVA improved to 0.6 - 1.2 while BCVA improved 0.7 - 1.2 postoperatively. BCVA improved more than 2 lines in 2 eyes whereas 1 line in 2 eyes. No eye lost BCVA. The difference between pre-and postoperative refraction was within ± 0.75 DS, an average of SE (-0.25 ± 0.33) DS. No epicenter showed in topography. Spherical aberration increased slightly in 8 eyes but decreased in 2 eyes. OCT showed that stroma bed fit to each other very well.
  
  
  CONCLUSIONS
  Femtosecond lenticule extraction appears to be efficiency, safety and predictable for myopia. Femtosecond lenticule extraction could have a good stroma fit. Its wavefront aberration changes need to further investigation.
authors: Department of Ophthalmology, Eye and ENT Hospital, Fudan University, Key Laboratory of Health Ministry for Myopia, Shanghai 200031, China. xingtaozhou@163.com
authors: Xing-tao
authors: XT
authors: Zhou
authors: Zi-xian
authors: ZX
authors: Dong
authors: Pei-jun
authors: PJ
authors: Yao
authors: Jia
authors: J
authors: Huang
authors: Ye
authors: Y
authors: Xu
authors: Hai-peng
authors: HP
authors: Xu
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D020731:Keratomileusis, Laser In Situ / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009216:Myopia / Q000601:surgery*; D011446:Prospective Studies; D055815:Young Adult