title: Effect of gestational weight gain on perinatal outcomes in women with type 2 diabetes mellitus using the 2009 Institute of Medicine guidelines.
abstract: OBJECTIVE
  We sought to examine associations between gestational weight gain according to the 2009 Institute of Medicine (IOM) guidelines and perinatal outcomes in overweight/obese women with type 2 diabetes mellitus (T2DM).
  
  
  METHODS
  This is a retrospective cohort study of 2310 women with T2DM enrolled in the California Diabetes and Pregnancy Program. Gestational weight gain was categorized by 2009 IOM guidelines. Perinatal outcomes were assessed using the χ(2) test and multivariable logistic regression analysis.
  
  
  RESULTS
  With excessive gestational weight gain, the odds of having large-for-gestational age (adjusted odds ratio [aOR], 2.00; 95% confidence interval [CI], 1.33-3.00) or macrosomic (aOR, 2.59; 95% CI, 1.56-4.30) neonates and cesarean delivery (aOR, 1.47; 95% CI, 1.03-2.10) was higher. Women with excessive gestational weight gain per week had increased odds of preterm delivery (aOR, 1.57; 95% CI, 1.11-2.20).
  
  
  CONCLUSIONS
  In overweight or obese women with T2DM, gestational weight gain greater than the revised IOM guidelines was associated with higher odds of perinatal morbidity, suggesting these guidelines are applicable to a diabetic population.
authors: Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco, CA, USA. yeelm@obgyn.ucsf.edu
authors: Lynn M
authors: LM
authors: Yee
authors: Yvonne W
authors: YW
authors: Cheng
authors: Maribeth
authors: M
authors: Inturrisi
authors: Aaron B
authors: AB
authors: Caughey
mesh_terms: D000328:Adult; D015992:Body Mass Index; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000503:physiopathology*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D015969:National Academies of Science, Engineering, and Medicine, U.S., Health and Medicine Division; D050177:Overweight / Q000150:complications / Q000503:physiopathology*; D011247:Pregnancy; D011256:Pregnancy Outcome; D011254:Pregnancy in Diabetics / Q000503:physiopathology*; D012189:Retrospective Studies; D014481:United States; D015430:Weight Gain / Q000502:physiology*