title: Use of cyclosporin in a patient with hepatitis C and pustular psoriasis.
abstract: Cyclosporine has been contraindicated in patients with chronic infections such as infection with hepatitis C because of its immunosuppressive effect. Recent studies have shown however that cyclosporine suppresses viral replication and thus cannot exacerbate infection with hepatitis C when employed for treating patients with psoriasis. We present the case of a female patient with psoriasis for 30 years and hepatitis C for 20 years, with diffuse circinate lesions. Improvement in the skin condition and liver enzymes was obtained with the use of cyclosporine, with no adverse effect.
authors: Hospital Universitário Pedro Ernesto, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brasil. lislainebomm@gmail.com
authors: Lislaine
authors: L
authors: Bomm
authors: Carolina Cotta
authors: CC
authors: Zimmermann
authors: Roberto
authors: R
authors: Souto
authors: Aline
authors: A
authors: Bressan
authors: Alexandre
authors: A
authors: Gripp
mesh_terms: D000368:Aged; D016572:Cyclosporine / Q000627:therapeutic use*; D003879:Dermatologic Agents / Q000627:therapeutic use*; D005260:Female; D006526:Hepatitis C / Q000150:complications*; D006801:Humans; D011565:Psoriasis / Q000150:complications / Q000188:drug therapy*
chemical_list: D003879:Dermatologic Agents; D016572:Cyclosporine