title: Enhancement characteristics of lymphomatous lymph nodes of the mediastinum.
abstract: BACKGROUND
  Previous studies of CT enhancement of lymphomatous lymph nodes (LLN) of the neck showed that the LLN had lower enhancement values than normal lymph nodes.
  
  
  OBJECTIVE
  To elucidate the contrast medium enhancement curves of LLN in the mediastinum by comparing the curves of LLN with those of normal lymph nodes, and to compare the present enhancement curves of LLN of the mediastinum with the curves of LLN of the neck from a previous similar investigation.
  
  
  METHODS
  Twenty-four consecutive patients with LLN in the mediastinum (9 with Hodgkin's lymphoma [HL]) and 23 control patients with sarcomas and thus presumably normal mediastinal nodes underwent dynamic CT examinations. The previous, similar investigation of lymph nodes of the neck comprised 28 patients with LLN and 20 control patients.
  
  
  RESULTS
  The enhancement curves of the mediastinal LLN had significantly lower values than those of the mediastinal control nodes. The LLN of the mediastinum had lower mean peak contrast values than the corresponding nodes of the neck from a previous investigation.
  
  
  CONCLUSIONS
  The comparison of enhancement curves of mediastinal LLN with mediastinal control nodes showed a marked similarity with and substantiates our previous findings in lymph nodes of the neck.
authors: Department of Radiology, Oslo University Hospital, Norway.
authors: Trond
authors: T
authors: Hagtvedt
authors: Trond Mogens
authors: TM
authors: Aaløkken
authors: Hans-Jørgen
authors: HJ
authors: Smith
authors: Bjørn Anton
authors: BA
authors: Graff
authors: Harald
authors: H
authors: Holte
authors: Alf
authors: A
authors: Kolbenstvedt
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D019540:Area Under Curve; D003287:Contrast Media; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007472:Iohexol; D008198:Lymph Nodes / Q000000981:diagnostic imaging; D008223:Lymphoma / Q000000981:diagnostic imaging*; D008297:Male; D008479:Mediastinal Neoplasms / Q000000981:diagnostic imaging*; D008482:Mediastinum / Q000000981:diagnostic imaging; D008875:Middle Aged; D012372:ROC Curve; D011856:Radiographic Image Enhancement / Q000379:methods*; D015203:Reproducibility of Results; D012509:Sarcoma / Q000000981:diagnostic imaging; D012680:Sensitivity and Specificity; D018709:Statistics, Nonparametric; D014057:Tomography, X-Ray Computed / Q000379:methods*; D055815:Young Adult
chemical_list: D003287:Contrast Media; D007472:Iohexol