title: [The significance of the expression of Col IV and LN in nasal and paranasal sinus malignant tumor].
abstract: OBJECTIVE
  To study the pathological relationship between the expression of Col IV and LN in nasal and paranasal sinus malignant tumor (NPMT).
  
  
  METHODS
  The immunohistochemical technique was used to detected the expression of Col IV and LN in NPMT, para-cancer tissues and non-cancer tissues.
  
  
  RESULTS
  There was a significance on the expression of the Col IV and LN in NPMT, para-cancer tissues and non-cancer tissues (P<0.01), and no significance in endepidermis and soft connective tissue of the NPMT (P>0.05).
  
  
  CONCLUSIONS
  The Col IV and LN perhaps participate in tumorigenesis of NPMT, and may play the homoioplastic role in different pathological types of the NPMT.
authors: Department of Otorhinolaryngology, Central Hospital Conde De S. Januario, Macau, China. moktinseak@gmail.com
authors: Tinseak
authors: T
authors: Mok
authors: Yanchun
authors: Y
authors: Shan
authors: Haiying
authors: H
authors: Jia
authors: Tao
authors: T
authors: Zhang
authors: Jiqun
authors: J
authors: Wang
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D024141:Collagen Type IV / Q000378:metabolism*; D005260:Female; D006801:Humans; D007797:Laminin / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D009296:Nasal Cavity / Q000473:pathology; D009669:Nose Neoplasms / Q000378:metabolism* / Q000473:pathology; D010255:Paranasal Sinus Neoplasms / Q000378:metabolism* / Q000473:pathology; D055815:Young Adult
chemical_list: D024141:Collagen Type IV; D007797:Laminin