title: In-hospital mortality among a cohort of cirrhotic patients admitted to a tertiary hospital.
abstract: OBJECTIVE
  To determine the mortality rate in a cohort of hospitalized patients with cirrhosis and examine their resuscitation status at admission.
  
  
  METHODS
  A retrospective chart review was conducted of patients with cirrhosis who were admitted to a tertiary care hospital in Riyadh, Saudi Arabia, from January 1, 2009, to December 31, 2009.
  
  
  RESULTS
  We reviewed 226 cirrhotic patients during the study period. The hospital mortality rate was 35%. A univariate analysis revealed that worse outcomes were seen in patients with advanced age or who had worse child-turcotte-pugh (CPT) scores, worse model for end-stage liver disease (MELD) scores, low albumin and high serum creatinine. Using a multivariate analysis, we found that advanced age (P=0.004) and high MELD (P=0.001) scores were independent risk factors for the mortality of cirrhotic patients. The end-of-life decision were made in 34% of cirrhotic patients, and the majority of deceased patients were "no resuscitation" status (90% vs. 4%, P<0.001).
  
  
  CONCLUSIONS
  The relatively high mortality in cirrhotic patients admitted for care in a tertiary hospital, Saudi Arabia was comparable to that reported in the literature. Furthermore, end-of-life discussions should be addressed early in the hospitalization of cirrhotic patients.
authors: Department of Intensive Care Medicine and Emergency Medicine, King Abdulaziz Medical City, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.
authors: Mohammad A
authors: MA
authors: Alsultan
authors: Rashed S
authors: RS
authors: Alrshed
authors: Abdulrahman A
authors: AA
authors: Aljumah
authors: Salim A
authors: SA
authors: Baharoon
authors: Yaseen M
authors: YM
authors: Arabi
authors: Abdulaziz S
authors: AS
authors: Aldawood
mesh_terms: D003657:Decision Making; D005260:Female; D005500:Follow-Up Studies; D017052:Hospital Mortality / Q000639:trends*; D006801:Humans; D007297:Inpatients; D008103:Liver Cirrhosis / Q000401:mortality* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012151:Resuscitation; D012189:Retrospective Studies; D012307:Risk Factors; D012529:Saudi Arabia / Q000453:epidemiology