title: Highly sensitive nonenzymatic glucose sensor based on electrospun copper oxide-doped nickel oxide composite microfibers.
abstract: An improved nonenzymatic glucose sensor based on copper oxide-doped nickel oxide composite microfibers (CuO-NiO-MFs) modified fluorine tin oxide (FTO) electrode was prepared by electrospinning and calcination technologies without using any immobilization. The results of cyclic voltammetry (CV) and chronoamperometry demonstrated that the CuO-NiO-MFs modified electrode displayed much higher electrocatalytic activity than the nickel oxide microfibers (NiO-MFs) modified electrode toward glucose. The nonenzymatic glucose sensor based on CuO-NiO-MFs showed the highest sensitivity of 3165.53 μA mM(-1)cm(-2) with the lowest detection limit of 1 × 10(-9)M (signal/noise ratio (S/N)=3) in the nonenzymatic glucose sensors that have been reported in the literature. Additionally, its application for detecting glucose concentration of human serum sample showed good agreement with the results obtained from automatic biochemical analyzer.
authors: Key Laboratory of Polyoxometalates Science of Ministry of Education, Northeast Normal University, Changchun 130024, PR China.
authors: Fei
authors: F
authors: Cao
authors: Shu
authors: S
authors: Guo
authors: Huiyan
authors: H
authors: Ma
authors: Guocheng
authors: G
authors: Yang
authors: Shengxue
authors: S
authors: Yang
authors: Jian
authors: J
authors: Gong
mesh_terms: D015374:Biosensing Techniques / Q000295:instrumentation / Q000379:methods*; D003300:Copper / Q000737:chemistry*; D055664:Electrochemical Techniques / Q000295:instrumentation / Q000379:methods*; D005947:Glucose / Q000032:analysis*; D006801:Humans; D057139:Nanofibers / Q000737:chemistry*; D009532:Nickel / Q000737:chemistry*
chemical_list: D003300:Copper; D009532:Nickel; C028007:nickel monoxide; D005947:Glucose; C000520:cuprous oxide