title: Spatio-temporal trends of Iberian wild boar contact with Mycobacterium tuberculosis complex detected by ELISA.
abstract: The continuing expansion of Eurasian wild boar (Sus scrofa) populations raises concerns regarding disease transmission. In south-central Spain, overabundant wild boar are reservoirs of Mycobacterium bovis, and related members of the Mycobacterium tuberculosis complex (MTBC), the causative agents of bovine tuberculosis (bTB). An indirect enzyme-linked immunosorbent assay using bovine-purified protein derivative was applied to determine the spatial and temporal distribution of wild boar contact with MTBC in the Iberian Peninsula and to model and identify the associated risk factors. Wild boar apparent seroprevalence was 22%. Seropositives were detected in 71% of 81 sites, including 23 sites where wildlife was thought to be bTB free. The results described a new geographic range of wild boar contact with MTBC and a stable prevalence in this wildlife reservoir that contrasts with the success of bTB control in cattle. Inference of which host (wild boar or cattle) is driving bTB maintenance was not possible with our correlational results. The possibility of a wild boar bTB emergence in non-endemic regions should urgently be taken into account to avoid a future scenario resembling the current situation in south-central Spain.
authors: Instituto de Investigación en Recursos Cinegéticos (CSIC-UCLM-JCCM), Ciudad Real, Spain. mariana.boadella@gmail.com
authors: Mariana
authors: M
authors: Boadella
authors: Pelayo
authors: P
authors: Acevedo
authors: Joaquín
authors: J
authors: Vicente
authors: Gregorio
authors: G
authors: Mentaberre
authors: Ana
authors: A
authors: Balseiro
authors: MariCruz
authors: M
authors: Arnal
authors: David
authors: D
authors: Martínez
authors: Ignacio
authors: I
authors: García-Bocanegra
authors: Carmen
authors: C
authors: Casal
authors: Julio
authors: J
authors: Álvarez
authors: Álvaro
authors: Á
authors: Oleaga
authors: Santiago
authors: S
authors: Lavín
authors: Marta
authors: M
authors: Muñoz
authors: Jose L
authors: JL
authors: Sáez-Llorente
authors: Jose
authors: J
authors: de la Fuente
authors: Christian
authors: C
authors: Gortázar
mesh_terms: D000818:Animals; D002417:Cattle; D004197:Disease Reservoirs / Q000662:veterinary; D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods; D009163:Mycobacterium bovis / Q000302:isolation & purification*; D009169:Mycobacterium tuberculosis / Q000302:isolation & purification*; D011174:Portugal / Q000453:epidemiology; D016036:Seroepidemiologic Studies; D013030:Spain / Q000453:epidemiology; D034421:Sus scrofa / Q000382:microbiology*; D013552:Swine; D013553:Swine Diseases / Q000453:epidemiology / Q000382:microbiology*; D014380:Tuberculosis, Bovine / Q000453:epidemiology