title: Dyslipidemias in type 2 diabetes mellitus patients in Nnewi South-East Nigeria.
abstract: BACKGROUND
  Dyslipidemia has been noted to play an integral role in the pathogenesis and progression of micro and macrovascular complications in diabetes mellitus patients. The complications exemplified by renal vascular and cardiovascular disease cause the most morbidity and mortality in this group of patients.
  
  
  OBJECTIVE
  This study is aimed at understanding the pattern of dyslipidemia among type 2 diabetic patients.
  
  
  METHODS
  A total of 108 consenting adult type 2 diabetic patients seen in the medical unit of the Nnamdi Azikiwe University Teaching Hospital Nnewi were evaluated in this crosssectional study. Their fasting lipid profile, fasting blood glucose, weight, height and blood pressure were evaluated.
  
  
  RESULTS
  The prevalence of dyslipidemia (at least one abnormal lipid profile) was 90.7%. The 24.1% had single dyslipidemia while 66.6% had combined dyslipidemia. Reduced HDL constituted the highest single abnormality (62%) followed by hypertriglyceridemia (56.5%), hypercholesterolemia (53.7%) and high LDL in (44.4%). The duration of DM was not significantly associated with dyslipidemia (P > 0.05).
  
  
  CONCLUSIONS
  Dyslipidemia is highly prevalent among type 2 diabetic patients in Nigeria with the majority of the patients having combined dyslipidemia. We recommend that aggressive treatment of lipidemia and hyperglycemia can be instituted to reduce the risk of macro and microvascular complications.
authors: Department of Medicine, Nnamdi Azikiwe University Teaching Hospital Nnewi, P.M.B 5025 Nnewi, Nigeria. nonjyske@yahoo.com
authors: N N
authors: NN
authors: Jisieike-Onuigbo
authors: E I
authors: EI
authors: Unuigbe
authors: C O
authors: CO
authors: Oguejiofor
mesh_terms: D016009:Chi-Square Distribution; D008076:Cholesterol, HDL / Q000097:blood; D003430:Cross-Sectional Studies; D003924:Diabetes Mellitus, Type 2 / Q000453:epidemiology* / Q000401:mortality / Q000473:pathology; D018450:Disease Progression; D050171:Dyslipidemias / Q000453:epidemiology* / Q000401:mortality / Q000473:pathology; D005260:Female; D006784:Hospitals, Teaching; D006801:Humans; D015228:Hypertriglyceridemia / Q000453:epidemiology / Q000401:mortality / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009549:Nigeria / Q000453:epidemiology; D015995:Prevalence; D018570:Risk Assessment
chemical_list: D008076:Cholesterol, HDL