title: Out-of-hospital cardiac arrest: recent advances in resuscitation and effects on outcome.
abstract: Successful treatment of out-of-hospital cardiac arrest remains an unmet health need. Key elements of treatment comprise early recognition of cardiac arrest, prompt and effective cardiopulmonary resuscitation (CPR), effective defibrillation strategies and organised post-resuscitation care. The initiation of bystander CPR followed by a prompt emergency response that delivers high quality CPR is critical to outcomes. The integration of additional tasks such as defibrillation, airway management, vascular access and drug administration should avoid interruptions in chest compressions. Evidence for the routine use of CPR prompt/feedback devices, mechanical chest compression devices and pharmacological therapy is limited.
authors: University of Warwick, Warwick Medical School, Warwick CV4 7AL, UK. g.d.perkins@warwick.ac.uk
authors: Gavin D
authors: GD
authors: Perkins
authors: Samantha J
authors: SJ
authors: Brace
authors: Mike
authors: M
authors: Smythe
authors: Giok
authors: G
authors: Ong
authors: Simon
authors: S
authors: Gates
mesh_terms: D016887:Cardiopulmonary Resuscitation / Q000379:methods / Q000592:standards*; D004562:Electrocardiography; D006801:Humans; D015994:Incidence; D058687:Out-of-Hospital Cardiac Arrest / Q000453:epidemiology / Q000503:physiopathology / Q000628:therapy; D015996:Survival Rate