title: Shrink-film configurable multiscale wrinkles for functional alignment of human embryonic stem cells and their cardiac derivatives.
abstract: A biomimetic substrate for cell-culture is fabricated by plasma treatment of a prestressed thermoplastic shrink film to create tunable multiscaled alignment "wrinkles". Using this substrate, the functional alignment of human embryonic stem cell derived cardiomyocytes is demonstrated.
authors: Department of Chemical Engineering and Material Science, University of California, Irvine, 92697, USA.
authors: Aaron
authors: A
authors: Chen
authors: Deborah K
authors: DK
authors: Lieu
authors: Lauren
authors: L
authors: Freschauf
authors: Valerie
authors: V
authors: Lew
authors: Himanshu
authors: H
authors: Sharma
authors: Jiaxian
authors: J
authors: Wang
authors: Diep
authors: D
authors: Nguyen
authors: Ioannis
authors: I
authors: Karakikes
authors: Roger J
authors: RJ
authors: Hajjar
authors: Ajay
authors: A
authors: Gopinathan
authors: Elliot
authors: E
authors: Botvinick
authors: Charless C
authors: CC
authors: Fowlkes
authors: Ronald A
authors: RA
authors: Li
authors: Michelle
authors: M
authors: Khine
mesh_terms: D000200:Action Potentials; D000818:Animals; D032701:Biomimetics; D002454:Cell Differentiation; D002478:Cells, Cultured; D053595:Embryonic Stem Cells / Q000166:cytology*; D004867:Equipment Design; D005434:Flow Cytometry / Q000379:methods; D006801:Humans; D008422:Materials Testing; D051379:Mice; D009206:Myocardium / Q000166:cytology*; D032383:Myocytes, Cardiac / Q000166:cytology*; D051381:Rats; D013234:Stem Cells / Q000166:cytology; D013499:Surface Properties