title: Psychosocial variables are associated with being wait-listed, but not with receiving a kidney transplant in the Dialysis Outcomes and Practice Patterns Study (DOPPS).
abstract: BACKGROUND
  Psychosocial factors are associated with clinical outcomes in patients with end-stage renal disease. It is not known if self-reported depression and quality of life influence the likelihood of being wait-listed and receiving a transplant.
  
  
  METHODS
  Prevalent cross section of 18- to 65-year-old hemodialysis (HD) patients in the USA (N = 2033) and seven European countries (N = 4350) from the Dialysis Outcomes and Practice Patterns Study phase II and III was analyzed. Wait-listed patients (N = 1838) were followed until kidney transplantation. Self-reported depressive symptoms were assessed by the Center for Epidemiologic Studies-Depression scale, 10-item version (CES-D) and health-related quality of life (HR-QoL) by the Kidney Disease Quality of Life Short Form 12 scale Physical Component Score (PCS).
  
  
  RESULTS
  At study entry, 27% (USA) to 53% (UK) of patients were wait-listed in participating countries. Variables associated with lower odds of being on the waiting list included worse HR-QoL, more severe depressive symptoms, older age, fewer years of education, lower serum albumin, lower hemoglobin, shorter time on dialysis and presence of multiple comorbid conditions. Among wait-listed patients, significantly lower transplantation rates were seen for females, blacks, patients having prior transplantation and multiple comorbid conditions but not PCS or CES-D.
  
  
  CONCLUSIONS
  Fewer depressive symptoms and better HR-QoL are associated with being on the waiting list in prevalent HD patients but not with receiving a kidney transplant among wait-listed dialysis patients. Regular assessment of subjective well-being may help identify patients with reduced access to wait-listing and kidney transplantation.
authors: Institute of Behavioral Sciences, Semmelweis University, Budapest, Hungary.
authors: Lilla
authors: L
authors: Szeifert
authors: Jennifer L
authors: JL
authors: Bragg-Gresham
authors: Jyothi
authors: J
authors: Thumma
authors: Brenda W
authors: BW
authors: Gillespie
authors: Istvan
authors: I
authors: Mucsi
authors: Bruce M
authors: BM
authors: Robinson
authors: Ronald L
authors: RL
authors: Pisoni
authors: Alex
authors: A
authors: Disney
authors: Christian
authors: C
authors: Combe
authors: Friedrich K
authors: FK
authors: Port
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D015331:Cohort Studies; D003430:Cross-Sectional Studies; D003863:Depression / Q000453:epidemiology; D005060:Europe; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D007676:Kidney Failure, Chronic / Q000453:epidemiology / Q000523:psychology* / Q000628:therapy*; D016030:Kidney Transplantation; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011584:Psychology; D011788:Quality of Life / Q000523:psychology; D006435:Renal Dialysis; D057566:Self Report; D014481:United States; D014850:Waiting Lists; D055815:Young Adult