title: Primary hepatic leiomyosarcoma: Case report and literature review.
abstract: Primary hepatic leiomyosarcoma are rare tumors with less than 30 cases reported in the English literature. Non specific presentations and often diagnosis delayed until they reach a large size, is the norm with therapy leading to an often dismal prognosis. A 67-year-old man presented complaining of abdominal pain and a palpable abdominal mass since Jan 2010. Abdominal ultrasonography and abdominal computed tomography revealed a large tumor in the left lobe of the liver. Surgical exploration was undertaken and an extended left hepatectomy with extension onto the dorsal part of segment 8 preserving the MHV with partial resection of segment 6 was undertaken. The weight of the resected specimen was 1300 g of the left lobectomy specimen and 8 g of the segment 6 partial resection specimen. The pathology report confirmed the diagnosis of leiomyosarcoma. On immunohistochemistry, the tumor cells were positive for smooth muscle actin stain. The patient is on regular follow up and is currently 9 mo post resection with no evidence of recurrence. We report the case of a resected primary hepatic leiomyosarcoma and emphasize the need for a global database for these rare tumors to promote a better and broader understanding of this less understood subject.
authors: Nairuthya Shivathirthan, Junji Kita, Yukihiro Iso, Hiroyuki Hachiya, Park KyungHwa, Tokihiko Sawada, Keiichi Kubota, Second Department of Surgery, Dokkyo Medical University, 880 Kita Kobayashi, Mibu, Tochigi 321-0293, Japan.
authors: Nairuthya
authors: N
authors: Shivathirthan
authors: Junji
authors: J
authors: Kita
authors: Yukihiro
authors: Y
authors: Iso
authors: Hiroyuki
authors: H
authors: Hachiya
authors: Park
authors: P
authors: Kyunghwa
authors: Tokihiko
authors: T
authors: Sawada
authors: Keiichi
authors: K
authors: Kubota