title: Treatment of peristomal pyoderma gangrenosum with topical crushed dapsone.
abstract: A 27-year-old male with a history of Crohn's disease was treated for chronic pyoderma gangrenosum at his stoma site. Treatment with topical application of crushed dapsone resulted in improvement of his pyoderma gangrenosum. Crushed dapsone may be an efficacious treatment with minimal systemic side effects. This appears to be the first case of pyoderma gangrenosum treated with crushed dapsone.
authors: University of Nebraska Medical Center, College of Medicine, Omaha, NE, USA.
authors: Marc Z
authors: MZ
authors: Handler
authors: Heather
authors: H
authors: Hamilton
authors: Daniel
authors: D
authors: Aires
mesh_terms: D000279:Administration, Cutaneous; D000328:Adult; D000890:Anti-Infective Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use; D003622:Dapsone / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D005500:Follow-Up Studies; D006801:Humans; D007081:Ileostomy / Q000009:adverse effects*; D008297:Male; D017511:Pyoderma Gangrenosum / Q000188:drug therapy* / Q000473:pathology; D016896:Treatment Outcome
chemical_list: D000890:Anti-Infective Agents; D003622:Dapsone