title: Examining the stability of DSM-IV and empirically derived eating disorder classification: implications for DSM-5.
abstract: OBJECTIVE
  The purpose of this investigation was to derive an empirical classification of eating disorder symptoms in a heterogeneous eating disorder sample using latent class analysis (LCA) and to examine the longitudinal stability of these latent classes (LCs) and the stability of DSM-IV eating disorder (ED) diagnoses.
  
  
  METHODS
  A total of 429 females with ED symptoms were assessed using the Eating Disorder Examination every 6 months for 2 years. LCA was used to derive empirical classification at baseline. Latent transition analysis (LTA) was used to examine the longitudinal stability of LCs, and Markov modeling procedures were used to examine DSM-IV ED diagnoses over all the time points.
  
  
  RESULTS
  LCA yielded a 3-class solution: binge eating and purging, binge eating only, and low body mass index. LTA indicated that these LCs showed greater stability over 2 years than DSM-IV diagnoses with the probability of remaining in the same class ranging from 0.69 to 0.91 for LCs and from 0.40 to 0.75 for DSM-IV diagnoses. Transition patterns also revealed more stability for LCs with only 21% changing classes compared with 63% of the DSM-IV diagnostic categories.
  
  
  CONCLUSIONS
  Empirically derived classes of ED symptoms showed greater longitudinal stability than DSM-IV diagnoses over a 2-year time period, suggesting that modifying the criteria to be consistent with empirically based classification (e.g., reducing frequency requirements of binge eating and purging) may reduce ED diagnostic crossover in DSM-5.
authors: Department of Psychiatry, University of Minnesota Medical School, Minneapolis, MN 55454-1495, USA. peter161@umn.edu
authors: Carol B
authors: CB
authors: Peterson
authors: Scott J
authors: SJ
authors: Crow
authors: Sonja A
authors: SA
authors: Swanson
authors: Ross D
authors: RD
authors: Crosby
authors: Stephen A
authors: SA
authors: Wonderlich
authors: James E
authors: JE
authors: Mitchell
authors: W Stewart
authors: WS
authors: Agras
authors: Katherine A
authors: KA
authors: Halmi
mesh_terms: D000328:Adult; D039721:Diagnostic and Statistical Manual of Mental Disorders; D001068:Feeding and Eating Disorders / Q000145:classification* / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008137:Longitudinal Studies