title: Incessant monomorphic ventricular tachycardia induced by the proarrhythmic effect of amiodarone.
abstract: This case report describes incessant monomorphic ventricular tachycardia (VT), not torsade de pointes, induced by intravenous amiodarone in a 48-year-old woman with dilated cardiomyopathy. VT was reproducibly triggered by short coupled premature ventricular complex (PVC) with different morphology from VT. After amiodarone infusion, the coupling interval of initiating PVC was prolonged, and moreover, the morphology of initiating PVC became the same as that of VT. Though amiodarone has become the first line drug to treat ventricular tachyarrhythmias in patients with cardiac dysfunction, it is important to be aware of its proarrhythmic effect, which may lead to an electrical storm of monomorphic VT.
authors: Division of Arrhythmia and Electrophysiology, Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Japan.
authors: Hisaki
authors: H
authors: Makimoto
authors: Takashi
authors: T
authors: Noda
authors: Takashi
authors: T
authors: Kurita
authors: Ikutaro
authors: I
authors: Nakajima
authors: Teruki
authors: T
authors: Yokoyama
authors: Atsushi
authors: A
authors: Doi
authors: Yuko
authors: Y
authors: Yamada
authors: Hideo
authors: H
authors: Okamura
authors: Kazuhiro
authors: K
authors: Satomi
authors: Takeshi
authors: T
authors: Aiba
authors: Wataru
authors: W
authors: Shimizu
authors: Kazuhiro
authors: K
authors: Suyama
authors: Naohiko
authors: N
authors: Aihara
authors: Shiro
authors: S
authors: Kamakura
mesh_terms: D000638:Amiodarone / Q000008:administration & dosage / Q000009:adverse effects*; D001145:Arrhythmias, Cardiac / Q000139:chemically induced / Q000175:diagnosis; D004562:Electrocardiography / Q000187:drug effects; D005260:Female; D006801:Humans; D007275:Injections, Intravenous; D008875:Middle Aged; D017180:Tachycardia, Ventricular / Q000139:chemically induced* / Q000175:diagnosis*
chemical_list: D000638:Amiodarone