title: How are tonoplast proteins degraded?
abstract: Protein turnover is fundamental both for development and cellular homeostasis. The mechanisms responsible for the turnover of integral membrane proteins in plant cells are however still largely unknown. Recently, considerable attention has been devoted to the degradation of plasma membrane proteins. We have now studied the turnover of a tonoplast protein, the potassium channel TPK1, in fully differentiated Arabidopsis leaf cells and showed that its degradation occurs upon internalization into the vacuole. Here, we discuss the possible mechanisms and triggering events involved.
authors: Istituto di Biologia e Biotecnologia Agraria, Consiglio Nazionale delle Ricerche, Milano, Italy.
authors: Marie
authors: M
authors: Maîtrejean
authors: Alessandro
authors: A
authors: Vitale
mesh_terms: D017360:Arabidopsis / Q000378:metabolism*; D029681:Arabidopsis Proteins / Q000378:metabolism*; D059828:Plant Cells / Q000378:metabolism; D018515:Plant Leaves / Q000378:metabolism; D015221:Potassium Channels / Q000378:metabolism*; D059748:Proteolysis; D014617:Vacuoles / Q000378:metabolism
chemical_list: D029681:Arabidopsis Proteins; D015221:Potassium Channels