title: Factors associated with lobar vs. non-lobar intracerebral hemorrhage.
abstract: OBJECTIVE
  The relationship between body mass index (BMI) and stroke subtypes has received more research attention than that between BMI and location of intracerebral hemorrhage (ICH). Lobar hemorrhage (LH) differs from non-LH primarily in terms of etiology, i.e. cerebral amyloid angiopathy is the main cause of LH. This study aimed to determine the relationship between BMI and ICH.
  
  
  METHODS
  In this retrospective study involving 460 consecutive patients with ICH, BMI was significantly lower in LH than for other ICH locations. BMI categories were underweight (BMI < 18.5 kg/m(2)), normal weight (18.5-23.0 kg/m(2)), overweight (23.0-27.5 kg/m(2)), or obesity (≥27.5 kg/m(2)). Outcome at 1 year was evaluated by the modified Rankin Scale (mRS). We investigated the relationship of BMI and other clinical characteristics with LH and non-LH.
  
  
  RESULTS
  LH was associated with age (>70 years), underweight, unfavorable outcome (mRS ≥3), and daily alcohol consumption. Hypertension and intraventricular bleeding were significantly less common in patients with LH than those with non-LH.
  
  
  CONCLUSIONS
  Alongside risk factors conventionally thought to be related to LH, underweight may also be a LH-related factor, specifically in the elderly.
authors: Department of Neurosurgery, St. Luke's International Hospital, Tokyo, Japan. mahide@luke.or.jp
authors: H
authors: H
authors: Matsukawa
authors: M
authors: M
authors: Shinoda
authors: M
authors: M
authors: Fujii
authors: O
authors: O
authors: Takahashi
authors: D
authors: D
authors: Yamamoto
authors: A
authors: A
authors: Murakata
authors: R
authors: R
authors: Ishikawa
mesh_terms: D000367:Age Factors; D000368:Aged; D000428:Alcohol Drinking / Q000009:adverse effects; D015992:Body Mass Index; D002543:Cerebral Hemorrhage / Q000453:epidemiology* / Q000209:etiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012307:Risk Factors; D013851:Thinness / Q000150:complications*