title: The synthesis of highly water-dispersible and targeted CdS quantum dots and it is used for bioimaging by confocal microscopy.
abstract: Synthesis of a highly dispersed hydrophilic CdS nanocrystals and their use as fluorescence labeling for live cell imaging is reported here. By carefully manipulating the surface of CdS nanocrystals, the dispersions of CdS-MAA-PEI-FA nanocrystals with high photostability is prepared. The receptor-mediated delivery of folic acid conjugated quantum dots into folate-receptor-positive cell lines such as CBRH7919 liver cancer cells was demonstrated by confocal microscopy. In the future, the further modified CdS nanoparticles can be used for the tissue imaging in vivo studies.
authors: Department of Pharmacy Science, Binzhou Medical College, Yantai, 264003, China.
authors: Guangcheng
authors: G
authors: Wei
authors: Miaomiao
authors: M
authors: Yan
authors: Liying
authors: L
authors: Ma
authors: Huaibin
authors: H
authors: Zhang
mesh_terms: D000818:Animals; D019187:Cadmium Compounds / Q000737:chemistry*; D045744:Cell Line, Tumor; D058973:Folate Receptors, GPI-Anchored / Q000378:metabolism*; D005492:Folic Acid / Q000032:analysis / Q000737:chemistry / Q000378:metabolism*; D008099:Liver / Q000166:cytology; D051379:Mice; D018613:Microscopy, Confocal; D045663:Quantum Dots; D013440:Sulfides / Q000737:chemistry*
chemical_list: D019187:Cadmium Compounds; D058973:Folate Receptors, GPI-Anchored; D013440:Sulfides; C034939:cadmium sulfide; D005492:Folic Acid