title: [Selection and spreading of antibiotic resistance in bacteria].
abstract: Use of an antibiotic may not only select for resistance against the agent itself, but may at the same time co-select for resistance against other antibiotics if resistance genes are linked on e.g. a plasmid. Resistance plasmids may also carry genes mediating resistance against metals and disinfectants. Therefore, abundant use of metals, e.g. copper and zinc for growth promotion in animals used for food, may also co-select for antibiotic resistance. The same applies to disinfectants, e.g. silver and chlorhexidine. Prudent use of antibiotics and these other agents is essential to control antibiotic resistance.
authors: Klinisk Mikrobiologisk Afdeling, Hvidovre Hospital, Kettegård Allé 30, 2650 Hvidovre, Denmark. niels.frimodt-moeller@hvh.regionh.dk
authors: Niels
authors: N
authors: Frimodt-Møller
authors: Hans Jørn
authors: HJ
authors: Kolmos
mesh_terms: D000822:Animal Husbandry; D000818:Animals; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000009:adverse effects; D004202:Disinfectants / Q000008:administration & dosage / Q000009:adverse effects; D024881:Drug Resistance, Bacterial / Q000187:drug effects / Q000235:genetics; D024901:Drug Resistance, Multiple, Bacterial / Q000187:drug effects / Q000235:genetics; D004363:Drug Utilization; D016984:Enterococcus faecium / Q000187:drug effects; D006801:Humans; D008670:Metals / Q000008:administration & dosage / Q000009:adverse effects; D011200:Poultry / Q000382:microbiology; D013552:Swine / Q000382:microbiology
chemical_list: D000900:Anti-Bacterial Agents; D004202:Disinfectants; D008670:Metals