title: Novel insights into FH-associated disease are KEAPing the lid on oncogenic HIF signalling.
authors: Julie
authors: J
authors: Adam
authors: Peter J
authors: PJ
authors: Ratcliffe
authors: Patrick J
authors: PJ
authors: Pollard
mesh_terms: D000818:Animals; D002471:Cell Transformation, Neoplastic / Q000378:metabolism*; D005649:Fumarate Hydratase / Q000235:genetics / Q000378:metabolism*; D006801:Humans; D051795:Hypoxia-Inducible Factor 1, alpha Subunit / Q000235:genetics / Q000378:metabolism*; D047908:Intracellular Signaling Peptides and Proteins / Q000235:genetics / Q000378:metabolism*; D000072019:Kelch-Like ECH-Associated Protein 1; D007680:Kidney Neoplasms / Q000235:genetics / Q000378:metabolism* / Q000473:pathology; D018231:Leiomyomatosis / Q000235:genetics / Q000378:metabolism* / Q000473:pathology; D009386:Neoplastic Syndromes, Hereditary / Q000235:genetics / Q000378:metabolism* / Q000473:pathology; D015398:Signal Transduction / Q000502:physiology*; D012878:Skin Neoplasms; D014594:Uterine Neoplasms
chemical_list: C497442:HIF1A protein, human; D051795:Hypoxia-Inducible Factor 1, alpha Subunit; D047908:Intracellular Signaling Peptides and Proteins; C431364:KEAP1 protein, human; D000072019:Kelch-Like ECH-Associated Protein 1; D005649:Fumarate Hydratase