title: Noncovalent organocatalysis: a powerful tool for the nucleophilic epoxidation of α-ylideneoxindoles.
abstract: A novel asymmetric nucleophilic epoxidation for α-ylideneoxindole esters has been successfully devised, resulting in enantioenriched spiro compounds with two new contiguous stereocenters. The employed (S)-α,α-diphenylprolinol functions as a bifunctional catalyst, creating a complex H-bond network in conjunction with a substrate and an oxidant.
authors: Department of Chemistry, Sapienza Università di Roma, p.le Aldo Moro 5, I-00185 Roma, Italy.
authors: Chiara
authors: C
authors: Palumbo
authors: Giuseppe
authors: G
authors: Mazzeo
authors: Andrea
authors: A
authors: Mazziotta
authors: Augusto
authors: A
authors: Gambacorta
authors: M Antonietta
authors: MA
authors: Loreto
authors: Antonella
authors: A
authors: Migliorini
authors: Stefano
authors: S
authors: Superchi
authors: Daniela
authors: D
authors: Tofani
authors: Tecla
authors: T
authors: Gasperi
mesh_terms: D002384:Catalysis; D004852:Epoxy Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D004952:Esters; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry*; D015394:Molecular Structure; D013141:Spiro Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D004852:Epoxy Compounds; D004952:Esters; D007211:Indoles; D013141:Spiro Compounds