title: Ruptured thoracoabdominal aneurysm in a 27-year-old with hyper IgE syndrome.
abstract: Hyperimmunoglobulin E syndrome is a rare primary immunodeficiency disorder defined by high serum immunoglobulin E titers and associated with characteristic infectious, dermatologic, skeletal, and dental abnormalities. We present the case of a 27-year-old man presenting acutely with a ruptured type IV thoracoabdominal aortic aneurysm. He was successfully treated by open operative repair and discharged with long-term prophylactic antibiotics. To our knowledge, this is the first such case reported in the English literature.
authors: Department of Vascular Surgery, Royal Infirmary of Edinburgh University Hospital, Edinburgh, United Kingdom. orwafalah@hotmail.com
authors: Orwa
authors: O
authors: Falah
authors: Stephen E
authors: SE
authors: Thwaites
authors: R T A
authors: RT
authors: Chalmers
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D017545:Aortic Aneurysm, Thoracic / Q000000981:diagnostic imaging / Q000209:etiology* / Q000601:surgery; D001019:Aortic Rupture / Q000000981:diagnostic imaging / Q000209:etiology* / Q000601:surgery; D001027:Aortography / Q000379:methods; D019917:Blood Vessel Prosthesis Implantation; D006801:Humans; D007589:Job Syndrome / Q000150:complications* / Q000235:genetics / Q000276:immunology; D008297:Male; D050796:STAT3 Transcription Factor / Q000235:genetics; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D050796:STAT3 Transcription Factor; C494086:STAT3 protein, human