title: [Frontiers in vitamin D; basic research and clinical application. Vitamin D deficiency, insufficiency and sufficiency].
abstract: In November 2010, IOM (Institute of Medicine) of USA issued a report on DRI (Dietary Reference Intakes) for calcium and vitamin D, which challenged then widespread view among many in US that vitamin D sufficiency is defined by serum 25 (OH) D level more than 30 ng/mL. The IOM report concluded serum 25 (OH) D level of 20 ng/mL would be sufficient for 97.5% of general healthy population, and recommended vitamin D intake much lower than that had been believed among many experts. After much discussion, disputes, in July 2011, American Endocrine Society issued a guideline for Vitamin D deficiency, which contrasted to IOM report in many aspects. In this article, differences between those two guidelines are reviewed and current issues surrounding vitamin D deficiency/sufficiency are discussed.
authors: Third Depatment of Medicine, Teikyo University Chiba Medical Center, Japan.
authors: Ryo
authors: R
authors: Okazaki
mesh_terms: D015415:Biomarkers / Q000097:blood; D006801:Humans; D006887:Hydroxycholecalciferols / Q000097:blood; D007564:Japan; D017410:Practice Guidelines as Topic; D014481:United States; D014807:Vitamin D / Q000008:administration & dosage*; D014808:Vitamin D Deficiency / Q000175:diagnosis / Q000517:prevention & control*
chemical_list: D015415:Biomarkers; D006887:Hydroxycholecalciferols; D014807:Vitamin D