title: [Borderline ovarian tumors and global radiation in relation with climate change impact].
abstract: There is limited information on borderline ovarian tumor detected intra-surgically and its most favorable treatment in relation with global radiation and climate changes.
  
  
  OBJECTIVE
  To study the pre-surgery and intra-surgery differentiation criteria of borderline ovarian tumors from invasive carcinoma, and to make a very complex analysis of the frequency, distribution, and variation in time of global radiation, temperature, and precipitation in North-East Romania.
  
  
  METHODS
  The 54 patients (age range 20-78 years, mean age 46 years) included in this study had borderline ovarian tumors surgically treated during the last 22 years (January 1988 - December 2009) at the 4th Gynecological Clinic at Iaşi, and representing 4.87% of the total 1107 ovarian tumors detected and treated during this interval. The histological types were: serous (18 cases), mucinous (27 cases), mixed (8 cases), and Brenner tumor (1 case). In order to analyze the impact of climate changes on borderline ovarian tumors a thorough study on the frequency of global radiation in relation with climate changes based on data recorded in the last 55 years was also carried out.
  
  
  RESULTS
  The distribution of these cases depending on when surgery was performed was analyzed. In our study the frequency of ovarian borderline tumors (4.87%) is lower than in similar reports in the literature being due, in our opinion, to the influence of global radiation in relation with climate changes.
  
  
  CONCLUSIONS
  In our study global radiation is probably responsible for a progression to invasive carcinoma in 0.7% of the borderline ovarian tumors.
authors: Universităţii de Medicină şi Farmacie "Gr. T. Popa" Iaşi.
authors: Alina-Mihaela
authors: AM
authors: Luchian
authors: M
authors: M
authors: Pricop
mesh_terms: D000328:Adult; D000368:Aged; D001948:Brenner Tumor / Q000453:epidemiology / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D002471:Cell Transformation, Neoplastic; D057231:Climate Change; D003359:Cosmic Radiation / Q000009:adverse effects*; D018291:Cystadenoma, Mucinous / Q000453:epidemiology / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D018293:Cystadenoma, Serous / Q000453:epidemiology / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D003937:Diagnosis, Differential; D018450:Disease Progression; D005260:Female; D057232:Global Warming; D006801:Humans; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D010051:Ovarian Neoplasms / Q000453:epidemiology / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D011379:Prognosis; D012189:Retrospective Studies; D012383:Romania / Q000453:epidemiology; D016896:Treatment Outcome