title: Melamine-related urinary stones in 195 infants and young children: clinical features within 2 years of follow-up.
abstract: OBJECTIVE
  To summarize the clinical features and follow-up, the effects of melamine-tainted milk powder (MMP) consumption on kidney and body growth in children who suffered from melamine-related urinary stones (MUS) 2 years earlier were checked.
  
  
  METHODS
  Body height and weight, kidney and bladder morphology monitored by ultrasound, urinalysis and renal function were recorded. Plain abdominal radiography was performed for differential diagnosis. The first follow-up was carried out at 15 months and the second 2 years later for patients who showed any abnormality at the first follow-up. Two hundred age- and gender-matched cohorts were included.
  
  
  RESULTS
  All cases received conservative treatment in hospital. Fifteen months of follow-up was successfully carried out in 167 cases. 91 children had residual MUS at the time of discharge, 58 MUS disappeared completely, 25 dissolved partially, 1 increased in size, and 7 did not change. At 2 years of follow-up, the residual stones all disappeared except for 1 case; the patient who showed a delayed development with regard to height caught up at 24 months of follow-up.
  
  
  CONCLUSIONS
  Conservative treatment shows a high effectiveness in cases with residual MUS. Consumption of MMP with timely treatment did not demonstrate an evident impact on kidney and bladder although body height is slightly affected in a few cases.
authors: Urodynamic Center, Department of Urology of the First Affiliated Hospital of Zhengzhou University, Institute of Clinical Medicine of Zhengzhou University, Zhengzhou, China. jgwen @ zzu.edu.cn
authors: Jian Guo
authors: JG
authors: Wen
authors: Qing Long
authors: QL
authors: Chang
authors: An Feng
authors: AF
authors: Lou
authors: Zhen Zhen
authors: ZZ
authors: Li
authors: Shan
authors: S
authors: Lu
authors: Yan
authors: Y
authors: Wang
authors: Ya Lun
authors: YL
authors: Wang
authors: Jin Hua
authors: JH
authors: Hu
authors: Shu Ping
authors: SP
authors: Mao
authors: Yan
authors: Y
authors: Zhang
authors: Rui
authors: R
authors: Xue
authors: Chuanchuan
authors: C
authors: Ren
authors: Lu
authors: L
authors: Xing
authors: Guo Xian
authors: GX
authors: Zhang
authors: Shengjun
authors: S
authors: Zhang
authors: Jens Christian
authors: JC
authors: Djurhuus
authors: Jørgen
authors: J
authors: Frøkiaer
mesh_terms: D001827:Body Height; D016022:Case-Control Studies; D016009:Chi-Square Distribution; D002657:Child Development; D002675:Child, Preschool; D002681:China; D005260:Female; D005500:Follow-Up Studies; D005506:Food Contamination; D006801:Humans; D007223:Infant; D041943:Infant Formula; D007668:Kidney / Q000254:growth & development; D008297:Male; D011379:Prognosis; D011859:Radiography; D012074:Remission Induction; D013997:Time Factors; D014227:Triazines / Q000009:adverse effects*; D001743:Urinary Bladder / Q000254:growth & development; D014545:Urinary Calculi / Q000139:chemically induced* / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000628:therapy
chemical_list: D014227:Triazines; C011907:melamine