title: Catestatin is useful in detecting patients with stage B heart failure.
abstract: Screening patients with stage B heart failure(HF) may be one strategy for reducing human morbidity. To describe catestatin levels in different stages of HF and evaluate the diagnostic utility of catestatin for detecting stage B HF, we included 300 patients. Catestatin, BNP testing and echocardiogram were performed. Our studies showed catestatin decreased gradually from stage A to C. There was significant difference between stage A and B. Cutoff value for detecting stage B HF was 19.73 ng/ml for catestatin with 90% sensitivity and 50.9% specificity. These results may have implications in the new method to detect patients with stage B HF.
authors: Department of Cardiology, Peking University Third Hospital, Beijing, China.
authors: Dan
authors: D
authors: Zhu
authors: Fangfang
authors: F
authors: Wang
authors: Haiyi
authors: H
authors: Yu
authors: Lin
authors: L
authors: Mi
authors: Wei
authors: W
authors: Gao
mesh_terms: D053379:Chromogranin A / Q000378:metabolism; D006333:Heart Failure / Q000175:diagnosis* / Q000378:metabolism; D006801:Humans; D010446:Peptide Fragments / Q000378:metabolism
chemical_list: D053379:Chromogranin A; D010446:Peptide Fragments; C109084:chromogranin A (344-364)