title: The tug-of-war between dendritic cells and human chronic viruses.
abstract: The human immune system is under constant challenge from many viruses, some of which the body is successfully able to clear. Other viruses have evolved to escape the host immune responses and thus persist, leading to the development of chronic diseases. Dendritic cells are professional antigen-presenting cells that play a major role in both innate and adaptive immunity against different pathogens. This review focuses on the interaction of different chronic viruses with dendritic cells and the viruses' ability to exploit this critical cell type to their advantage so as to establish persistence within the host.
authors: Department of Microbiology and Immunology, Drexel Institute for Biotechnology and Virology Research, Drexel University College of Medicine, 3805 Old Easton Road, Doylestown, PA 18902, USA.
authors: Saifur
authors: S
authors: Rahman
authors: Zafar K
authors: ZK
authors: Khan
authors: Pooja
authors: P
authors: Jain
mesh_terms: D000938:Antigen-Presenting Cells; D002908:Chronic Disease; D003713:Dendritic Cells / Q000166:cytology / Q000276:immunology* / Q000821:virology*; D006801:Humans; D014777:Virus Diseases / Q000276:immunology* / Q000821:virology; D014780:Viruses / Q000276:immunology* / Q000472:pathogenicity