title: New triterpenoid saponins from Patrinia scabiosaefolia.
abstract: Phytochemical investigation of the methanol extract from the whole plants of Patrinia scabiosaefolia Fisch. resulted in the isolation of four new triterpenoid saponins (1-4) along with six known compounds (5-10). On the basis of spectroscopic and chemical methods, the structures of the new compounds were established as 3-O-β-D-xylopyranosyl-(1→3)-α-L-rhamnopyranosyl-(1→2)-β-D-xylopyranosyl-12β,30-dihydroxy-olean-28,13β-olide (1), 3-O-α-L-rhamnopyranosyl-(1→2)-β-D-xylopyranosyl-12β,30-dihydroxy-olean-28,13β-olide (2), 3-O-β-D-xylopyranosyl-(1→2)-β-D-glucopyranosyl-12β, 30-dihydroxy-olean-28,13β-olide (3), and 3-O-β-D-glucopyranosyl-(1→4)-β-D-xylopyranosyl-(1→3)-α-L-rhamnopyranosyl-(1→2)-β-D-xylopyranosyl-oleanolic acid 28-O-β-D-glucopyranoside (4), respectively. Compounds 1-3 possess a novel 12β,30-dihydroxy-olean-28,13β-lactone aglycone and a 12β-hydroxy substituent that is rarely found in this kind of triterpenoid saponin.
authors: College of Pharmaceutical Science, Soochow University, Suzhou 215123, Jiangsu Province, China.
authors: Liang
authors: L
authors: Gao
authors: Lin
authors: L
authors: Zhang
authors: Nan
authors: N
authors: Li
authors: Jiang-Yun
authors: JY
authors: Liu
authors: Pei-Lie
authors: PL
authors: Cai
authors: Shi-Lin
authors: SL
authors: Yang
mesh_terms: D002240:Carbohydrate Sequence; D008968:Molecular Conformation; D008969:Molecular Sequence Data; D032405:Patrinia / Q000737:chemistry*; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification*; D012503:Saponins / Q000737:chemistry / Q000302:isolation & purification*; D013237:Stereoisomerism; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification*
chemical_list: D010936:Plant Extracts; D012503:Saponins; D014315:Triterpenes