title: Diet and prostate cancer - a holistic approach to management.
abstract: There is now increasing evidence from epidemiologic surveys and from laboratory, intervention, and case-control studies that diet and lifestyle plays a crucial role in prostate cancer biology and tumorigenesis. This applies to both the development and progression of prostate cancer, although in many cases the specific initiating factors in the diet are poorly understood. Conversely, many nutrients and herbs also show significant promise in helping to treat prostate cancer by slowing progression and reducing recurrence, ultimately reducing the risk of morbidity and mortality from the disease. Furthermore for all grades of prostate cancer, nutritional interventions complement conventional treatment to improve response and quality of life. Slowing or even reversing the progression of, high-grade prostate intraepithelial neoplasia [HGPIN]). with chemo-preventative agents could be the best primary defense against prostate cancer, preventing it from occurring in the first place. The information given in this review about prostate cancer chemoprevention summarizes the key evidence for the role of different dietary components and their effect on prostate cancer prevention and progression. Most nutritional chemoprevention agents also have the added benefit of being beneficial for the cardiovascular system, bone health and for the prevention of other cancers.
authors: Department of Oncology, Columbia University Medical Center, New York, NY 10032, USA. pcheethame@doctors.org.uk
authors: Philippa J
authors: PJ
authors: Cheetham
authors: Aaron E
authors: AE
authors: Katz
mesh_terms: D000230:Adenocarcinoma / Q000178:diet therapy / Q000188:drug therapy / Q000453:epidemiology / Q000209:etiology* / Q000517:prevention & control*; D000975:Antioxidants / Q000627:therapeutic use; D015897:Comorbidity; D003611:Dairy Products / Q000009:adverse effects; D004032:Diet / Q000009:adverse effects; D004041:Dietary Fats / Q000009:adverse effects; D019468:Disease Management; D006694:Holistic Health; D006801:Humans; D008297:Male; D008460:Meat / Q000009:adverse effects; D009765:Obesity / Q000453:epidemiology; D008517:Phytotherapy; D028321:Plant Preparations / Q000627:therapeutic use; D010945:Plants, Edible; D019048:Prostatic Intraepithelial Neoplasia / Q000178:diet therapy / Q000188:drug therapy / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control; D011471:Prostatic Neoplasms / Q000178:diet therapy / Q000188:drug therapy / Q000453:epidemiology / Q000209:etiology* / Q000517:prevention & control*; D055502:Secondary Prevention; D057185:Sedentary Behavior
chemical_list: D000975:Antioxidants; D004041:Dietary Fats; D028321:Plant Preparations