title: Phytic acid derived bioactive CaO-P2O5-SiO2 gel-glasses.
abstract: The possibility of using phytic acid as a precursor to synthesize CaO-P(2)O(5)-SiO(2) glasses by sol-gel method has been explored and the pseudo ternary phase diagram has been established. It was shown that gel-glasses over a broader range of compositions could be prepared compared to other phosphorus precursors or melt-quenching method. Furthermore, phytic acid was found to assist calcium being incorporated into glass networks. In vitro tests in simulated body fluid (SBF) were performed on the above gel-glasses and it was found that they were bioactive over a much broader compositional range especially at high phosphate content, thus enabling one to design bioactive materials with various degradation rates by adjusting the phosphate content.
authors: Beijing National Laboratory for Molecular Sciences, State Key Laboratory of Polymer Physics and Chemistry, Institute of Chemistry, Chinese Academy of Sciences, Beijing, China.
authors: Ailing
authors: A
authors: Li
authors: Dong
authors: D
authors: Qiu
mesh_terms: D001672:Biocompatible Materials / Q000737:chemistry*; D001826:Body Fluids; D017610:Calcium Compounds / Q000737:chemistry; D002516:Ceramics / Q000737:chemistry*; D000431:Ethanol / Q000737:chemistry; D005782:Gels; D006801:Humans; D007477:Ions; D008855:Microscopy, Electron, Scanning; D009566:Nitrates / Q000737:chemistry; D044367:Phase Transition; D010710:Phosphates / Q000737:chemistry; D010833:Phytic Acid / Q000737:chemistry*; D010949:Plasma / Q000737:chemistry; D012825:Silicon / Q000737:chemistry; D013696:Temperature; D013818:Thermogravimetry; D014867:Water / Q000737:chemistry; D014961:X-Ray Diffraction
chemical_list: D001672:Biocompatible Materials; D017610:Calcium Compounds; D005782:Gels; D007477:Ions; D009566:Nitrates; D010710:Phosphates; C416205:calcium oxide-silicon dioxide-diphosphorus pentoxide glass; D014867:Water; D000431:Ethanol; D010833:Phytic Acid; C059948:calcium nitrate; D012825:Silicon