title: Bioactive glass S53P4 and autograft bone in treatment of depressed tibial plateau fractures - a prospective randomized 11-year follow-up.
abstract: The clinical and radiological outcomes of bioactive glass (BAG)-S53P4 and autograft bone (AB) used as bone-graft substitutes in depressed tibial plateau fractures were evaluated in a prospective randomized 11-year follow-up study. All patients (n = 29) had sustained tibial plateau fractures with a joint-line depression of >3 mm. Fifteen patients (5 patients the BAG group, 10 patients in the AB group) participated in this long-term follow-up. X-rays were taken preoperatively, postoperatively, and at the long-term follow-up, and computed tomography (CT) scans were made at the long-term follow-up for evaluation of the bone substitute, osteoarthritis, the tibial-femoral angle, and deviation of mechanical axes. No material-dependent adverse effects were seen in any patient. The means of the articular surface depression on X-rays at the long-term follow-up were 1.4 mm (range: 0-2 mm) in the BAG group and 1.4 mm (range: 0-4 mm) in the AB group, and on CT scans the means were 2.2 mm (range: 2-3 mm), and 2.1 mm (range: 0-3), respectively. No significant difference in the tibial-femoral angle or deviation of mechanical axes was observed between the two groups. BAG-S53P4 can be used as a bone substitute in depressed lateral tibial plateau fractures with good functional and radiological long-term results.
authors: Department of Orthopedics and Traumatology, Turku University Hospital, Turku, Finland.
authors: K
authors: K
authors: Pernaa
authors: I
authors: I
authors: Koski
authors: K
authors: K
authors: Mattila
authors: E
authors: E
authors: Gullichsen
authors: J
authors: J
authors: Heikkila
authors: A
authors: A
authors: Aho
authors: Nina
authors: N
authors: Lindfors
mesh_terms: D000328:Adult; D000368:Aged; D018786:Bone Substitutes / Q000627:therapeutic use*; D005260:Female; D005500:Follow-Up Studies; D017102:Fracture Healing; D005898:Glass; D006801:Humans; D007085:Ilium / Q000637:transplantation*; D007719:Knee Joint / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D010147:Pain Measurement; D011446:Prospective Studies; D013978:Tibial Fractures / Q000601:surgery*; D014057:Tomography, X-Ray Computed; D014182:Transplantation, Autologous
chemical_list: D018786:Bone Substitutes; C403922:bioactive glass S53P4