title: Pharmacogenetics and age-related macular degeneration.
abstract: Pharmacogenetics seeks to explain interpatient variability in response to medications by investigating genotype-phenotype correlations. There is a small but growing body of data regarding the pharmacogenetics of both nonexudative and exudative age-related macular degeneration. Most reported data concern polymorphisms in the complement factor H and age-related maculopathy susceptibility 2 genes. At this time, the data are not consistent and no definite conclusions may be drawn. As clinical trials data continue to accumulate, these relationships may become more apparent.
authors: Bascom Palmer Eye Institute, Miller School of Medicine, University of Miami, 311 9th Street North, No. 100, Naples, FL 34102, USA.
authors: Stephen G
authors: SG
authors: Schwartz
authors: Milam A
authors: MA
authors: Brantley