title: Acute appendicitis, a rare complication of varicella: a report of three cases.
abstract: Acute appendicitis is a very rare complication of varicella, and is rarely reported in studies of complications of varicella or appendicitis. This report describes three cases of acute appendicitis in the course of varicella, diagnosed in Clinical Department of Infectious Diseases at Split University Hospital, Croatia between 1998 and 2010. Varicella was diagnosed clinically, and in two cases confirmed by positive serological tests for varicella-zoster virus (VZV). In addition to routine histopathological examination, testing for viral antigens or DNA in the appendix, omentum and peripheral blood by genetic and immunohistochemistry methods may be important to confirm whether VZV and appendicitis are etiopathogenetically connected.
authors: Clinical Department of Infectious Diseases, Split University Hospital and Split University Medical School, Šoltanska 1, Split, Croatia. boris.luksic1@st.t-com.hr
authors: Boris
authors: B
authors: Lukšić
authors: Suzana
authors: S
authors: Mladinov
authors: Ivana
authors: I
authors: Goić-Barišić
authors: Ante
authors: A
authors: Srzić
authors: Ivica
authors: I
authors: Brizić
authors: Ljiljana
authors: L
authors: Perić
mesh_terms: D000208:Acute Disease; D000328:Adult; D000914:Antibodies, Viral / Q000097:blood; D001062:Appendectomy; D001064:Appendicitis / Q000150:complications* / Q000473:pathology / Q000601:surgery; D002644:Chickenpox / Q000150:complications* / Q000175:diagnosis; D002648:Child; D017523:Croatia; D014645:Herpesvirus 3, Human / Q000276:immunology; D006801:Humans; D008297:Male; D055815:Young Adult
chemical_list: D000914:Antibodies, Viral