title: Association between biofuel exposure and adverse birth outcomes at high altitudes in Peru: a matched case-control study.
abstract: Nearly one-third of the Peruvian population burns biofuels for cooking. Similarly, approximately one-third of this population lives at high altitudes. Cooking with biofuels and living at high altitudes have been implicated in adverse perinatal outcomes. This study attempted to determine the risk of low birth weight (LBW) and/or preterm delivery in relation to biofuel use in inhabitants at high altitudes in Peru. A matched-case study was performed in two high-altitude cities. All subjects (n=190) were identified from public-hospital records. Cases were matched by hospital by week of birth and area of residence. Cases were defined as: women with an at-term but LBW newborn; or women with a preterm birth. Adjusted conditional logistic regression analyses were used to determine odds ratio. Fifty-two percent of the cases used biofuel whereas only 30% of the controls used biofuel. The use of biofuel for cooking was found to be strongly associated with increased risks of LBW, but was not significantly linked to preterm births.
authors: Instituto de Investigaciones de la Altura, Faculty of Sciences and Philosophy, Universidad Peruana Cayetano Heredia, Lima, Peru. Sandra.yucra@upch.pe
authors: Sandra
authors: S
authors: Yucra
authors: Vilma
authors: V
authors: Tapia
authors: Kyle
authors: K
authors: Steenland
authors: Luke P
authors: LP
authors: Naeher
authors: Gustavo F
authors: GF
authors: Gonzales
mesh_terms: D000293:Adolescent; D000328:Adult; D016902:Air Pollution, Indoor / Q000009:adverse effects*; D000531:Altitude; D056804:Biofuels / Q000009:adverse effects*; D016022:Case-Control Studies; D004560:Electricity / Q000009:adverse effects; D005260:Female; D006753:Hospital Records; D006801:Humans; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D007648:Kerosene / Q000009:adverse effects; D016015:Logistic Models; D008875:Middle Aged; D010568:Peru / Q000453:epidemiology; D011247:Pregnancy; D011256:Pregnancy Outcome; D047928:Premature Birth / Q000453:epidemiology* / Q000209:etiology*; D011407:Propane / Q000009:adverse effects; D012307:Risk Factors; D055815:Young Adult
chemical_list: D056804:Biofuels; D007648:Kerosene; D011407:Propane