title: Polymorphism of the growth hormone gene and its association with growth traits in Boer goat bucks.
abstract: In the present study, the polymorphism of growth hormone (GH) gene was analyzed as a genetic marker candidate for growth traits in Boer goat bucks. Two single nucleotide polymorphisms (SNPs) - A781G (Ser/Gly35) and A1575G (Leu147), were identified by GH gene sequencing and PCR-RFLP (polymerase chain reaction-restriction fragment length polymorphism) analysis. AA genotype resulted in a significant decrease in birth chest girth (P=0.03) and weaning weight (P=0.014) comparing to AB genotype, while CC genotype contributed to weaning height (P=0.04) greater than CD genotype. When in combination, AACD genotype was undesired for lower scores in a series of growth traits including body weight, length, height, and chest girth at birth and weaning, as well as the pre-weaning daily gain and body weight at age of 11 months. These results indicate that new molecular markers associated with caprine growth traits can be used in MAS (marker-assisted selection) in Boer goat bucks.
authors: College of Animal Science and Technology, Key Laboratory under Education Ministry of China for Agricultural Animal Genetics, Breeding, and Reproduction, Huazhong Agricultural University, Shizi Street, Wuhan, Hubei 430070, China.
authors: G H
authors: GH
authors: Hua
authors: S L
authors: SL
authors: Chen
authors: J N
authors: JN
authors: Yu
authors: K L
authors: KL
authors: Cai
authors: C J
authors: CJ
authors: Wu
authors: Q L
authors: QL
authors: Li
authors: C Y
authors: CY
authors: Zhang
authors: A X
authors: AX
authors: Liang
authors: L
authors: L
authors: Han
authors: L Y
authors: LY
authors: Geng
authors: Z
authors: Z
authors: Shen
authors: D Q
authors: DQ
authors: Xu
authors: L G
authors: LG
authors: Yang