title: Killing two birds with one salicylate: aspirin's dual roles in preventative health.
abstract: In a recent article published in The Lancet, investigators studied the impact of daily aspirin use on subsequent cancer deaths. Utilizing data from more than 25,000 patients enrolled in 8 large trials, which were originally intended to study the impact of daily aspirin use on the incidence of cardiovascular events, the authors found a substantial decrease in risk of fatal solid organ malignancies. In particular, the risk reduction was specific to adenocarcinomas. The findings from this study are highly relevant to the thoracic surgeon, with adenocarcinomas of the lung and esophagus among those tumors demonstrating the most profound risk reduction.
authors: Division of Thoracic and Foregut Surgery, Department of Surgery, University of Minnesota, Minneapolis, Minnesota 55455, USA.
authors: Mara B
authors: MB
authors: Antonoff
authors: Jonathan
authors: J
authors: D'Cunha
mesh_terms: D000230:Adenocarcinoma / Q000401:mortality / Q000517:prevention & control; D000077192:Adenocarcinoma of Lung; D016588:Anticarcinogenic Agents / Q000627:therapeutic use*; D001241:Aspirin / Q000627:therapeutic use*; D002317:Cardiovascular Agents / Q000627:therapeutic use*; D002318:Cardiovascular Diseases / Q000401:mortality / Q000517:prevention & control*; D004938:Esophageal Neoplasms / Q000401:mortality / Q000517:prevention & control; D006801:Humans; D015994:Incidence; D008175:Lung Neoplasms / Q000401:mortality / Q000517:prevention & control; D009369:Neoplasms / Q000401:mortality / Q000517:prevention & control*; D011314:Preventive Health Services; D018570:Risk Assessment; D012307:Risk Factors
chemical_list: D016588:Anticarcinogenic Agents; D002317:Cardiovascular Agents; D001241:Aspirin