title: Oral manifestation associated with multiple pituitary hormone deficiency and ectopic neurohypophysis.
abstract: Multiple pituitary hormone deficiency (MPHD) is the diminished secretion of all the hormones produced in the anterior lobe of the pituitary gland. The oral manifestation of this condition includes delayed eruption and prolonged retention of primary teeth, delayed formation and eruption of permanent teeth, delay in development and growth of the jaws, tendency towards development of deep bite and enamel disturbances. This paper reports the case of an adolescent patient with MPHD. Clinical examination revealed partial ankylosis and prolonged retention ofprimary second molars, primary maxillary canines and deep bite. Dental treatment included extraction of all molars with prolonged retention preceded by the necessary medical care with clinical and radiographic follow-up afterwards. The patient was also referred to an orthodontist for orthodontic treatment. Patients' medical condition should always be investigated by clinicians when faced with cases of delayed tooth eruption and bone development.
authors: Restorative Dentistry Department, School of Dentistry, University of São Paulo, Brazil. tais.sca@usp.br
authors: T
authors: T
authors: Scaramucci
authors: C A B
authors: CA
authors: Guglielmi
authors: R D
authors: RD
authors: Fonoff
authors: C G D
authors: CG
authors: Zardetto
mesh_terms: D002648:Child; D002828:Choristoma / Q000150:complications* / Q000503:physiopathology*; D003481:Cuspid / Q000503:physiopathology; D004967:Estrogens / Q000627:therapeutic use; D005260:Female; D019382:Human Growth Hormone / Q000627:therapeutic use; D006801:Humans; D008963:Molar / Q000503:physiopathology; D057887:Overbite / Q000209:etiology / Q000628:therapy; D010904:Pituitary Gland, Posterior; D010908:Pituitary Hormones, Anterior / Q000172:deficiency*; D011241:Prednisone / Q000627:therapeutic use; D013974:Thyroxine / Q000627:therapeutic use; D020254:Tooth Ankylosis; D014080:Tooth Exfoliation; D014081:Tooth Extraction; D014094:Tooth, Deciduous / Q000503:physiopathology / Q000601:surgery
chemical_list: D004967:Estrogens; D010908:Pituitary Hormones, Anterior; D019382:Human Growth Hormone; D013974:Thyroxine; D011241:Prednisone