title: Long-term brain and behavioral consequences of early iron deficiency.
abstract: Early iron deficiency not only affects brain and behavioral function during the period of iron deficiency, it persists long after treatment. The mechanisms include long-term alterations in dopamine metabolism, myelination, and hippocampal structure and function. Recent studies have demonstrated long-term genomic changes, which suggests the regulation of brain function is fundamentally altered.
authors: Center for Neurobehavioral Development, University of Minnesota School of Medicine and College of Education and Human Development, Minneapolis, Minnesota 55455, USA. georg001@umn.edu
authors: Michael K
authors: MK
authors: Georgieff
mesh_terms: D000367:Age Factors; D018798:Anemia, Iron-Deficiency / Q000473:pathology* / Q000523:psychology*; D000818:Animals; D001519:Behavior; D004298:Dopamine / Q000378:metabolism; D006624:Hippocampus / Q000378:metabolism*; D006801:Humans; D023421:Models, Animal; D011181:Postnatal Care; D009435:Synaptic Transmission; D013997:Time Factors
chemical_list: D004298:Dopamine