title: In situ replacement for mycotic aneurysms on the thoracic and abdominal aorta using rifampicin-bonded grafting and omental pedicle grafting.
abstract: BACKGROUND
  The objective of this report is to discuss the efficacy of in situ replacement for treating mycotic aneurysm, particularly using rifampicin-bonded grafts and omental pedicle grafts, on the basis of our 7 years of experience.
  
  
  METHODS
  Between December 2003 and December 2010, we performed surgical treatments in 23 patients (for the thoracic aorta in 6 patients, for the thoracoabdominal aorta in 8 patients, and for the abdominal aorta in 9 patients; 7 emergency, 10 urgent, and 6 elective operations) with mycotic aneurysm by using rifampicin-bonded grafting and omental pedicle grafting.
  
  
  RESULTS
  One patient died in hospital because of local recurrent infection. One patient required an additional operation on another aortic site, and 3 patients had spinal cord injuries (2 transient and 1 permanent). Overall survival at 5 years was 95%, and the rate of freedom from aortic events at 5 years was 86%.
  
  
  CONCLUSIONS
  In situ replacement using rifampicin-bonded grafting and omental pedicle grafting is effective for treating mycotic aneurysms of the thoracic and abdominal aorta.
authors: Department of Cardiovascular Surgery, Hiroshima City Asa General Hospital, and Department of Surgery, Hiroshima University, Hiroshima, Japan. uchidacv@hiroshima-u.ac.jp
authors: Naomichi
authors: N
authors: Uchida
authors: Akira
authors: A
authors: Katayama
authors: Kentaro
authors: K
authors: Tamura
authors: Sutoh
authors: S
authors: Miwa
authors: Kuraoka
authors: K
authors: Masatsugu
authors: Taijiro
authors: T
authors: Sueda
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000785:Aneurysm, Infected / Q000188:drug therapy / Q000601:surgery*; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D017544:Aortic Aneurysm, Abdominal / Q000188:drug therapy / Q000601:surgery*; D017545:Aortic Aneurysm, Thoracic / Q000188:drug therapy / Q000601:surgery*; D016470:Bacteremia / Q000150:complications / Q000188:drug therapy; D019917:Blood Vessel Prosthesis Implantation / Q000379:methods*; D003131:Combined Modality Therapy; D017558:Elective Surgical Procedures; D004756:Enterobacteriaceae Infections / Q000188:drug therapy / Q000601:surgery; D005260:Female; D016908:Gram-Positive Bacterial Infections / Q000188:drug therapy / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D009852:Omentum; D011093:Polyethylene Terephthalates; D012189:Retrospective Studies; D012293:Rifampin / Q000494:pharmacology; D015607:Stents; D013524:Surgical Flaps; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D011093:Polyethylene Terephthalates; D012293:Rifampin