title: Prenatal high-dose immunoglobulin treatment for neonatal hemochromatosis: a case report and review of the literature.
abstract: Neonatal hemochromatosis is a difficult disorder to cure, and it has a high rate of recurrence. High-dose immunoglobulin treatment is very effective as prenatal treatment for recurrent neonatal hemochromatosis. A 34-year-old pregnant Japanese woman underwent high-dose immunoglobulin treatment for recurrent neonatal hemochromatosis. High-dose non-specific intravenous immunoglobulin (1 g/kg bodyweight) was administered to the mother intravenously every week from 18 until 36 gestational weeks. A male infant was delivered at 37 weeks of gestation, and his condition was favorable, including hepatic function. The use of γ-globulin for neonatal hemochromatosis appears adequately validated by experience.
authors: Departments of Perinatology and Gynecology, Kagawa University School of Medicine, Kagawa, Japan. hiroka@med.kagawa-u.ac.jp
authors: Hirokazu
authors: H
authors: Tanaka
authors: Reiji
authors: R
authors: Haba
authors: Susumu
authors: S
authors: Itoh
authors: Haruhiko
authors: H
authors: Sakamoto
authors: Toshiyuki
authors: T
authors: Hata
mesh_terms: D000328:Adult; D005260:Female; D006432:Hemochromatosis / Q000188:drug therapy*; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use*; D007223:Infant; D007231:Infant, Newborn; D008111:Liver Function Tests; D008297:Male; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy*; D011295:Prenatal Care; D016896:Treatment Outcome
chemical_list: D016756:Immunoglobulins, Intravenous