title: A multiplexed 1,440 and 1,320 nm laser for treatment of chronic photodamage.
abstract: OBJECTIVE
  The purpose of this study is to quantify the safety and effectiveness of a multiplexed 1,440 and 1,320 nm fractionated laser for the treatment of chronic photodamage.
  
  
  METHODS
  A total of twenty subjects with chronic photodamage were enrolled in this study. Subjects received a maximum of four full-face treatments at an average fluence of 9.5 J/cm2 at 1,320 nm and 2 J/cm2 at 1,450 nm, delivered sequentially using forced-air cooling, at monthly intervals. Digital photographs were taken two months following the final treatment and compared to pre-treatment photographs by two blinded physician observers.
  
  
  RESULTS
  Improvement in photodamage, overall appearance, wrinkles, hyper-pigmentation, enlarged pores, and sagging skin was rated by blinded physician evaluation of digital photographs as being in the 25-50 percent range. Subjective ratings averaged improved for all criteria that were evaluated, including wrinkles, enlarged pores, redness, sagging skin and hyper-pigmentation.
  
  
  CONCLUSIONS
  The multiplexed 1,320 nm and 1,440 nm fractionated laser improves cutaneous photodamage as assessed by objective and subjective criteria.
authors: Main Line Center for Laser Surgery, Ardmore, PA, USA.
authors: Eric F
authors: EF
authors: Bernstein
mesh_terms: D000328:Adult; D000368:Aged; D003357:Cosmetic Techniques; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D053685:Laser Therapy / Q000009:adverse effects / Q000379:methods*; D008297:Male; D008875:Middle Aged; D010781:Photography; D015595:Skin Aging; D012880:Skin Pigmentation; D016896:Treatment Outcome; D014466:Ultraviolet Rays / Q000009:adverse effects*