title: Active surveillance criteria for prostate cancer: can they be applied to Japanese patients?
abstract: Prostate-specific antigen screening has significantly increased the percentage of men who are diagnosed with low-risk prostate cancer. All men undergoing retropubic radical prostatectomy for primary treatment of prostate cancer from April 2004 to September 2010 in our hospital were examined in order to determine whether active surveillance criteria could be applied to Japanese men. From pathological data of prostate biopsies, whether these men met five published criteria for active surveillance (Johns Hopkins Medical Institution, Prostate Cancer Research International: Active Surveillance Study, University of California, San Francisco, Toronto and Kakehi criteria) was evaluated. Men who met any of the criteria had a statistically significant lower extracapsular extension rate and organ-confinement rate. From the view of the possibility of Gleason upgrading and organ-confinement rate, the Johns Hopkins Medical Institution and Prostate Cancer Research International: Active Surveillance Study criteria showed to be appropriate for Japanese patients. However, the present study had limitations of selection bias and a limited number of cases.
authors: Department of Urology, Yokohama Rosai Hospital, Yokohama, Kanagawa, Japan. ygoto0213@gmail.com
authors: Yusuke
authors: Y
authors: Goto
authors: Kazuyoshi
authors: K
authors: Nozumi
authors: Kanetaka
authors: K
authors: Miyazaki
authors: Akihiro
authors: A
authors: Matsumoto
authors: Atsushi
authors: A
authors: Inoue
authors: Hiroki
authors: H
authors: Kito
authors: Naoki
authors: N
authors: Hasegawa
authors: Maki
authors: M
authors: Nagata
authors: Yukio
authors: Y
authors: Kakuta
authors: Hiroyoshi
authors: H
authors: Suzuki
authors: Kunio
authors: K
authors: Yamaguchi
mesh_terms: D000368:Aged; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D007564:Japan / Q000453:epidemiology; D008297:Male; D008403:Mass Screening / Q000379:methods*; D008875:Middle Aged; D060787:Neoplasm Grading / Q000379:methods*; D009367:Neoplasm Staging / Q000379:methods*; D011159:Population Surveillance; D011471:Prostatic Neoplasms / Q000175:diagnosis* / Q000453:epidemiology; D012189:Retrospective Studies; D012307:Risk Factors