title: A rare case of recurrent ovarian cancer presenting as a round ligament metastasis.
abstract: We report a rare case of recurrent ovarian cancer presenting as a round ligament metastasis. A 44-year-old woman presented with a lower abdominal mass. Computed tomography showed a pelvic mass. Primary surgery was performed. A histopathological examination showed an ovarian serous adenocarcinoma of Stage IIIb. The patient received 6 cycles of paclitaxel and carboplatin. Almost 2 years after the initial operation, the patient noticed a left inguinal mass. Computed tomography showed a left inguinal mass, 18 mm in size. An excisional biopsy was performed and the tumor was found to originate in the left round ligament. A histopathological examination showed serous adenocarcinoma and there was no evidence of lymph node tissue. Recurrence of ovarian cancer in the round ligament is extremely rare. This unique case suggests, however, that the round ligament in rare cases may be a recurrence site for ovarian cancer, and that accurate differentiation including confirmation by diagnostic imaging and excisional biopsy, is necessary for a definitive pathological diagnosis.
authors: Division of Gynecology, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan. stogami@ncc.go.jp
authors: Shinichi
authors: S
authors: Togami
authors: Tomoyasu
authors: T
authors: Kato
authors: Takateru
authors: T
authors: Oi
authors: Mitsuya
authors: M
authors: Ishikawa
authors: Takashi
authors: T
authors: Onda
authors: Shun-ichi
authors: S
authors: Ikeda
authors: Takahiro
authors: T
authors: Kasamatsu
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D016190:Carboplatin / Q000008:administration & dosage; D018284:Cystadenocarcinoma, Serous / Q000188:drug therapy / Q000556:secondary*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007264:Inguinal Canal / Q000473:pathology*; D010051:Ovarian Neoplasms / Q000188:drug therapy / Q000473:pathology*; D017239:Paclitaxel / Q000008:administration & dosage; D011379:Prognosis; D012404:Round Ligament of Uterus / Q000473:pathology*; D014057:Tomography, X-Ray Computed
chemical_list: D016190:Carboplatin; D017239:Paclitaxel