title: Folding-promoted TBACl-mediated chemo- and regioselective demethylations of methoxybenzene-based macrocyclic pentamers.
abstract: Tetrabutylammonium chloride (TBACl) salt alone has not been shown previously to be capable of removing methoxy groups. It is demonstrated here that the use of TBACl achieves efficient folding-promoted chemo- and regioselective demethylations, eliminating up to two out of five methyl groups situated in similar macrocyclic chemical microenvironments.
authors: College of Chemistry and Chemical Engineering, Chongqing University, Chongqing, China 400030.
authors: Bo
authors: B
authors: Qin
authors: Liuyin
authors: L
authors: Jiang
authors: Sheng
authors: S
authors: Shen
authors: Chang
authors: C
authors: Sun
authors: Weixing
authors: W
authors: Yuan
authors: Sam F Y
authors: SF
authors: Li
authors: Huaqiang
authors: H
authors: Zeng
mesh_terms: D008745:Methylation; D008958:Models, Molecular; D015394:Molecular Structure; D000644:Quaternary Ammonium Compounds / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000644:Quaternary Ammonium Compounds; C009405:tetrabutylammonium