title: General approach to allenes through copper-catalyzed γ-selective and stereospecific coupling between propargylic phosphates and alkylboranes.
abstract: Copper-catalyzed γ-selective coupling between propargylic phosphates and alkylboron compounds (alkyl-9-BBN, prepared by hydroboration of alkenes with 9-BBN-H) affords multisubstituted allenes with various functional groups. The reaction of enantioenriched propargylic phosphates to give axially chiral allenes proceeds with excellent point-to-axial chirality transfer with 1,3-anti stereochemistry.
authors: Department of Chemistry, Faculty of Science, Hokkaido University, Sapporo 060-0810, Japan. ohmiya@sci.hokudai.ac.jp
authors: Hirohisa
authors: H
authors: Ohmiya
authors: Umi
authors: U
authors: Yokobori
authors: Yusuke
authors: Y
authors: Makida
authors: Masaya
authors: M
authors: Sawamura