title: First experiences with hysterosalpingo-foam sonography (HyFoSy) for office tubal patency testing.
abstract: BACKGROUND
  This study was conducted to describe the first experiences with hysterosalpingo-foam sonography (HyFoSy) as a first step routine office procedure for tubal patency testing.
  
  
  METHODS
  A prospective observational cohort study was started in a university affiliated teaching hospital. In 2010, 73 patients with subfertility and a low risk of tubal pathology were examined. A non-toxic foam containing hydroxymethylcellulose and glycerol was applicated through a cervical applicator for contrast sonography (HyFoSy). Tubal patency was determined by transvaginal ultrasonographic demonstration of echogenic dispersion of foam in the Fallopian tube and/or the peritoneal cavity. Only in case patency could not be demonstrated, a hysterosalpingography (HSG) was performed as a control.
  
  
  RESULTS
  In 67 out of 73 (92%) patients, a successful procedure was performed. In 57 out of 73 (78%) cases, there was no further need for a HSG. In five patients (5/73; 7%) tubal occlusion was confirmed by HSG and in five patients (5/73; 7%) there was discordance between HyFoSy and HSG. Of 73 patients, 14 (19%) conceived within a median of 3 months after the procedure.
  
  
  CONCLUSIONS
  HyFoSy is a successful procedure to demonstrate tubal patency as a first step office procedure.
authors: Department of Obstetrics and Gynaecology, Spaarne Ziekenhuis Heemstede/Hoofddorp, PO Box 770, 2130 AT Hoofddorp, The Netherlands. m@emanuel.nl
authors: Mark Hans
authors: MH
authors: Emanuel
authors: Michelle
authors: M
authors: van Vliet
authors: Maaike
authors: M
authors: Weber
authors: Niek
authors: N
authors: Exalto
mesh_terms: D000328:Adult; D003287:Contrast Media / Q000494:pharmacology; D005184:Fallopian Tube Diseases / Q000175:diagnosis / Q000000981:diagnostic imaging*; D005186:Fallopian Tube Patency Tests / Q000379:methods*; D005187:Fallopian Tubes / Q000000981:diagnostic imaging / Q000473:pathology; D005260:Female; D006801:Humans; D007047:Hysterosalpingography / Q000379:methods*; D007246:Infertility / Q000175:diagnosis / Q000000981:diagnostic imaging*; D011247:Pregnancy; D011446:Prospective Studies; D014463:Ultrasonography / Q000379:methods
chemical_list: D003287:Contrast Media