title: Echinopsacetylenes A and B, new thiophenes from Echinops transiliensis.
abstract: Two new polyacetylene thiophenes, echinopsacetylenes A and B (1 and 2), were isolated from the roots of Echinops transiliensis. The structures of 1 and 2 were elucidated on the basis of spectroscopic analyses and chemical transformations. Echinopsacetylenes A (1) is the first natural product possessing an α-terthienyl moiety covalently linked with another thiophene moiety. Echinopsacetylenes B (2) is the first natural thiophene conjugated with a fatty acid moiety. Echinopsacetylene A (1) showed toxicity against the Formosoan subterranean termite (Coptotermes formosanus).
authors: NARO Kyushu Okinawa Agricultural Research Center, 496 Izumi, Chikugo, Fukuoka 833-0041, Japan. nakanohr@affrc.go.jp
authors: Hiroshi
authors: H
authors: Nakano
authors: Charles L
authors: CL
authors: Cantrell
authors: Leonid K
authors: LK
authors: Mamonov
authors: Weste L A
authors: WL
authors: Osbrink
authors: Samir A
authors: SA
authors: Ross
mesh_terms: D000818:Animals; D031182:Echinops Plant / Q000737:chemistry*; D007306:Insecticides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D020049:Isoptera / Q000187:drug effects*; D015394:Molecular Structure; D018517:Plant Roots / Q000737:chemistry; D053279:Polyynes; D013876:Thiophenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: D007306:Insecticides; D013876:Thiophenes; C569603:echinopsacetylene A; C569604:echinopsacetylene B; D053279:Polyynes