title: Selective monobenzoylation of 1,2- and 1,3-diols catalyzed by Me2SnCl2 in water (organic solvent free) under mild conditions.
abstract: We have developed an efficient method for selective monobenzoylation of 1,2- and 1,3-diols in water catalyzed by Me(2)SnCl(2). Treatment of 1,2- and 1,3-diols with benzoyl chlorides, DMT-MM, and potassium carbonate in the presence of a catalytic amount of Me(2)SnCl(2) and DMAP in water at room temperature gave monobenzoates in up to 97% yield.
authors: Graduate School of Biomedical Sciences, Nagasaki University, 1-14 Bunkyo-machi, Nagasaki, Nagasaki 852-8521, Japan. muramatu@nagasaki-u.ac.jp
authors: Wataru
authors: W
authors: Muramatsu
authors: Julius M
authors: JM
authors: William
authors: Osamu
authors: O
authors: Onomura
mesh_terms: D000438:Alcohols / Q000737:chemistry*; D002384:Catalysis; D015394:Molecular Structure; D009025:Morpholines / Q000737:chemistry*; D012997:Solvents / Q000737:chemistry*; D013237:Stereoisomerism; D017971:Tin Compounds / Q000737:chemistry*; D014867:Water / Q000737:chemistry*
chemical_list: C467606:4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride; D000438:Alcohols; D009025:Morpholines; D012997:Solvents; D017971:Tin Compounds; D014867:Water