title: Synthesis of biaryls via AlCl3 catalyzed domino reaction involving cyclization, dehydration, and oxidation.
abstract: A new chemical access has been developed to synthesize biaryls from substituted acetophenones, phenylacetones, dihydrochalcone, and 2-acetylnaphthalene in reasonably good yields at room temperature via a domino reaction sequence of AlCl(3) catalyzed cyclization, dehydration, and then oxidation.
authors: Medicinal and Process Chemistry Division, CSIR-Central Drug Research Institute, Lucknow-226001, U.P., India. t_narendra@cdri.res.in
authors: Tadigoppula
authors: T
authors: Narender
authors: Satinath
authors: S
authors: Sarkar
authors: Kandikonda
authors: K
authors: Rajendar
authors: Sriniwas
authors: S
authors: Tiwari
mesh_terms: D000096:Acetone / Q000031:analogs & derivatives* / Q000737:chemistry*; D000098:Acetophenones / Q000737:chemistry*; D000077410:Aluminum Chloride; D017607:Aluminum Compounds / Q000737:chemistry*; D001713:Biphenyl Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D047188:Chalcones / Q000737:chemistry*; D002712:Chlorides / Q000737:chemistry*; D020650:Combinatorial Chemistry Techniques; D003500:Cyclization; D003681:Dehydration; D015394:Molecular Structure; D009281:Naphthalenes / Q000737:chemistry*; D010084:Oxidation-Reduction
chemical_list: D000098:Acetophenones; D017607:Aluminum Compounds; D001713:Biphenyl Compounds; D047188:Chalcones; D002712:Chlorides; D009281:Naphthalenes; D000096:Acetone; C503376:2-acetylnaphthalene; D000077410:Aluminum Chloride