title: High rates of intestinal colonization with extended-spectrum lactamase-producing Enterobacteriaceae among healthy individuals.
abstract: BACKGROUND
  Infections caused by extended-spectrum β-lactamase (ESBL)-producing bacteria become an emerging problem in the community setting in many parts of the world.
  
  
  OBJECTIVE
  The objective of the study was to determine fecal carriage of ESBL-producing organisms in a community setting.
  
  
  METHODS
  A total of 632 fecal specimens from healthy individuals were screened for ESBL using the agar screening test with MacConkey agar plates supplemented with 1 μg/mL of cefotaxime for selection of ESBL-producing strains and confirmed by the Clinical Laboratory Standards Institute combined disk method.
  
  
  RESULTS
  Four hundred isolates (63.3%) were ESBL producers. Two hundred eighty-five isolates (71.25%) of them were Escherichia coli and 96 (24.0%) Klebsiella pneumoniae.
  
  
  CONCLUSIONS
  We concluded that the community could be a reservoir of these ESBL-producing bacteria and enzymes.
authors: Department of Clinical Microbiology, Cairo University, Cairo, Egypt. eimanmousa@yahoo.com
authors: Eiman Mohammed
authors: EM
authors: Abdul Rahman
authors: Rasha Hamed
authors: RH
authors: El-Sherif
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000890:Anti-Infective Agents / Q000494:pharmacology; D015169:Colony Count, Microbial; D004755:Enterobacteriaceae / Q000187:drug effects / Q000201:enzymology* / Q000302:isolation & purification; D004926:Escherichia coli / Q000187:drug effects / Q000201:enzymology / Q000302:isolation & purification; D005243:Feces / Q000382:microbiology; D006262:Health; D006801:Humans; D007422:Intestines / Q000187:drug effects / Q000382:microbiology*; D007711:Klebsiella pneumoniae / Q000187:drug effects / Q000201:enzymology / Q000302:isolation & purification; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D055815:Young Adult; D001618:beta-Lactamases / Q000096:biosynthesis*
chemical_list: D000890:Anti-Infective Agents; D001618:beta-Lactamases