title: Determination of paracetamol based on its quenching effect on the photoluminescence of CdTe fluorescence probes.
abstract: L-Cysteine capped CdTe nanoparticles (NPs) were synthesized in aqueous medium, and their application as fluorescence probes in the determination of paracetamol was studied. The L-cysteine capped CdTe NPs were characterized by transmission electron microscopy, X-ray diffraction spectrometry, spectrofluorometry, ultraviolet-visible and Fourier transform infrared spectrometry. Based on the distinct fluorescence quenching of CdTe fluorescence probes in the presence of paracetamol, a simple, rapid and specific method for paracetamol determination was presented. Under optimum conditions, the relative fluorescence intensity of CdTe NPs was linearly proportional to paracetamol concentration from 1.0 × 10(-8) mol/L to 1.6 × 10(-7) mol/L with a detection limit of 4.2 × 10(-9) mol/L. The proposed method was applied to detect paracetamol in commercial tablets with satisfactory results.
authors: Department of Chemistry, Shanghai University, Shanghai, People's Republic of China.
authors: Li
authors: L
authors: Li
authors: Yaxiang
authors: Y
authors: Lu
authors: Yaping
authors: Y
authors: Ding
authors: Yu
authors: Y
authors: Cheng
authors: Wanchen
authors: W
authors: Xu
authors: Fenfen
authors: F
authors: Zhang
mesh_terms: D000082:Acetaminophen / Q000032:analysis*; D019187:Cadmium Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D003545:Cysteine / Q000737:chemistry; D005456:Fluorescent Dyes / Q000138:chemical synthesis / Q000737:chemistry*; D049449:Luminescence; D053758:Nanoparticles / Q000737:chemistry; D010316:Particle Size; D013499:Surface Properties; D013691:Tellurium / Q000737:chemistry*
chemical_list: D019187:Cadmium Compounds; D005456:Fluorescent Dyes; D000082:Acetaminophen; D003545:Cysteine; D013691:Tellurium; C028337:cadmium telluride