title: Acute renal failure in orthopaedic surgery.
abstract: Orthopaedic diseases affect a broad spectrum of patients, and many of these have concomitant medical problems that may differ from those of the general surgical population. Acute postoperative renal failure is thought to arise secondary to acute tubular necrosis from volume depletion, reduction in glomerular filtration rate, hypotension, and nephrotoxic drugs. If acute renal failure occurs and necessitates hemodialysis, morbidity and mortality are significantly increased. To enhance the literature, we performed this study to review the rates and risk factors for acute renal failure in orthopaedic surgery. This information may be useful for orthopaedic surgeons and treating physicians during the rehabilitation stage, to provide a rationale to stratify a patient's risk of acute renal failure or death on the basis of perioperative medical factors and type of surgery, or for improved perioperative monitoring, better surveillance, and preventive measures to reduce this risk.
authors: First Department of Orthopaedics, Athens University Medical School, Athens, Greece.
authors: Andreas
authors: A
authors: Mavrogenis
authors: Evanthia A
authors: EA
authors: Mitsiokapa
authors: Matteo
authors: M
authors: Romantini
authors: Valeria
authors: V
authors: Grandinetti
authors: Luis
authors: L
authors: Coll-Mesa
authors: Pietro
authors: P
authors: Ruggieri
authors: Panayiotis J
authors: PJ
authors: Papagelopoulos
mesh_terms: D058186:Acute Kidney Injury / Q000209:etiology*; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000009:adverse effects; D001843:Bone Cements / Q000737:chemistry; D006801:Humans; D019637:Orthopedic Procedures; D011183:Postoperative Complications; D012206:Rhabdomyolysis / Q000150:complications; D012307:Risk Factors
chemical_list: D000900:Anti-Bacterial Agents; D001843:Bone Cements