title: A comparison of methods of post-operative analgesia in children undergoing limb reconstruction with circular frames.
abstract: This retrospective study compared post-operative epidural analgesia (E), continuous peripheral nerve blocks (CPNB) and morphine infusion (M) in 68 children undergoing limb reconstruction with circular frames. The data collected included episodes of severe pain, post-operative duration of analgesia, requirement for top-up analgesia, number of osteotomies, side effects and complications. There was a significant difference between the number of episodes of severe pain in patients receiving a morphine infusion and those receiving epidurals or CPNB (M vs E, p < 0.0001; M vs CPNB, p = 0.018). The CPNB group was associated with the lowest incidence of episodes of severe pain and top-up analgesia. Epidural analgesia was associated with significantly more nausea and vomiting than morphine infusion (p = 0.053) and CPNB (p = 0.023). It also had a significantly higher incidence of motor blockade than CPNB (p < 0.01). We found that the most effective method of post-operative analgesia for children undergoing lower limb reconstruction was sciatic nerve catheterisation and continuous infusion.
authors: Royal Manchester Children's Hospital, Oxford Road, Manchester M13 9WL, UK.
authors: E
authors: E
authors: Wells-Cole
authors: A
authors: A
authors: Griffiths
authors: D
authors: D
authors: Fines
authors: M
authors: M
authors: Zenios
mesh_terms: D000293:Adolescent; D000698:Analgesia / Q000009:adverse effects / Q000379:methods*; D015360:Analgesia, Epidural / Q000009:adverse effects / Q000379:methods; D000701:Analgesics, Opioid / Q000008:administration & dosage; D002648:Child; D002675:Child, Preschool; D004334:Drug Administration Schedule; D016267:External Fixators; D005260:Female; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D009020:Morphine / Q000008:administration & dosage; D009407:Nerve Block / Q000009:adverse effects / Q000379:methods; D019857:Osteogenesis, Distraction / Q000379:methods*; D010027:Osteotomy / Q000009:adverse effects / Q000379:methods; D010149:Postoperative Pain / Q000517:prevention & control*; D011182:Postoperative Care / Q000379:methods; D020250:Postoperative Nausea and Vomiting / Q000139:chemically induced; D012189:Retrospective Studies
chemical_list: D000701:Analgesics, Opioid; D009020:Morphine