title: Production of fluorous-based microarrays with uncharged carbohydrates.
abstract: Fluorous-based carbohydrate microarrays provide an alternative to traditional covalent microarray -platforms for probing protein-carbohydrate-binding interactions. The most studied plant lectin, concanavalin A (ConA), is known to bind to terminally α-linked mannose. In the studies presented, the binding of ConA with α-mannose is analyzed using a microarray formed on a fluorous-coated glass slide with the sugar containing a fluorous tag at the anomeric position.
authors: Department of Chemistry, The Plant Sciences Institute, and the Interdepartmental Program in Microbiology, Iowa State University, Ames, IA, USA.
authors: Sahana K
authors: SK
authors: Nagappayya
authors: Nicola L B
authors: NL
authors: Pohl
mesh_terms: D003208:Concanavalin A / Q000737:chemistry; D005461:Fluorine / Q000737:chemistry*; D008358:Mannose / Q000737:chemistry*; D046228:Microarray Analysis / Q000379:methods*
chemical_list: D003208:Concanavalin A; D005461:Fluorine; D008358:Mannose