title: Modulation and elimination of yeast prions by protein chaperones and co-chaperones.
abstract: The yeast system has provided considerable insight into the biology of amyloid and prions. Here we focus on how alterations in abundance or function of protein chaperones and co-chaperones affect propagation of yeast prions. In spite of a considerable amount of information, a clear understanding of the molecular mechanisms underlying these effects remains wanting.
authors: Laboratory of Biochemistry and Genetics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA.
authors: Michael
authors: M
authors: Reidy
authors: Daniel C
authors: DC
authors: Masison
mesh_terms: D005656:Fungal Proteins / Q000737:chemistry / Q000378:metabolism*; D006360:Heat-Shock Proteins / Q000737:chemistry / Q000378:metabolism*; D008958:Models, Molecular; D011328:Prions / Q000737:chemistry / Q000378:metabolism*
chemical_list: D005656:Fungal Proteins; D006360:Heat-Shock Proteins; D011328:Prions