title: Highly enantioselective one-pot synthesis of spirocyclopentaneoxindoles containing the oxime group by organocatalyzed Michael addition/ISOC/fragmentation sequence.
abstract: A highly diastereo- and enantioselective organocatalytic protocol for the synthesis of biologically important spirocyclopentaneoxindoles containing the oxime functional group from easily accessible 3-allyl-substituted oxindoles and nitroolefins has been developed by a one-pot Michael addition/ISOC/fragmentation sequence.
authors: Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education, School of Chemical Science and Technology, Yunnan University, Kunming 650091, China.
authors: Xiang
authors: X
authors: Li
authors: Ying-Mei
authors: YM
authors: Li
authors: Fang-Zhi
authors: FZ
authors: Peng
authors: Shou-Tao
authors: ST
authors: Wu
authors: Ze-Qian
authors: ZQ
authors: Li
authors: Zhong-Wen
authors: ZW
authors: Sun
authors: Hong-Bin
authors: HB
authors: Zhang
authors: Zhi-Hui
authors: ZH
authors: Shao
mesh_terms: D002384:Catalysis; D003500:Cyclization; D003517:Cyclopentanes / Q000138:chemical synthesis* / Q000737:chemistry; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D010091:Oximes / Q000737:chemistry*; D000078183:Oxindoles; D013141:Spiro Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D003517:Cyclopentanes; D007211:Indoles; D010091:Oximes; D000078183:Oxindoles; D013141:Spiro Compounds; C022960:2-oxindole