title: [Comparision of adsorption-desorption dynamics of huanglian jiedu decoction using different macroporous resins combinations].
abstract: OBJECTIVE
  To establish the techniques for the purification of Huanglian Jiedu decoction by macroporous resins combinations, and to lay the foundation of improvement of dosage forms in clinical application and realization of industrialized production about Huanglian Jiedu decoction.
  
  
  METHODS
  Four kinds of macroporous resins (X-5, S-8, HPD100, AB-8) were chosen and combined in six different forms. Adsorption and desorption experiments were carried out and contents of six index constituents, gardenoside, baicalin, palmatine, berberine, baicalein and wogonin, in different groups were compared before and after purification.
  
  
  RESULTS
  Adsorption rates of six index constituents in Huanglian Jiedu decoction of different combinations of macroporous resins groups were all nearly 100%, but desorption rates had remarkable differences.
  
  
  CONCLUSIONS
  Through comprehensive comparison, macroporous resins combination 6 resulted in high contents of index suitable relatively. It is suitable for purification of Huanglian Jiedu decoction.
authors: Key Laboratory of Separation Engineering of Chinese Traditional Medicine Compound, Nanjing University of Chinese Medicine, Nanjing 210029, China.
authors: Bihan
authors: B
authors: Qiu
authors: Huan
authors: H
authors: Li
authors: Linmei
authors: L
authors: Pan
authors: Huaxu
authors: H
authors: Zhu
authors: Liwei
authors: L
authors: Guo
mesh_terms: D000327:Adsorption; D002626:Chemistry, Pharmaceutical; D002853:Chromatography, Liquid; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification*
chemical_list: D004365:Drugs, Chinese Herbal; C494417:huanglian