title: Incorporation of in situ exposure and biomarkers response in clams Ruditapes philippinarum for assessment of metal pollution in coastal areas from the Maluan Bay of China.
abstract: The clams Ruditapes philippinarum were used to assess the impact of metal contaminants when transplanted to seven study sites along the Maluan Bay (China). Metal concentrations in digestive gland tissues of clams after 7-day in situ cage exposure were determined in conjunction with antioxidant enzyme activities. The results showed the importance of specific antioxidant biomarkers to assess complex pollutant mixtures and their good correlations to the pollutant compositions of deployment sites. Multivariate analysis indicated causal relationship between the chemicals at each study site and the biochemical "response" of the caged clams at these sites and demonstrated the potential presence of two different contaminant sources. This study suggested that the incorporation of tissue residue analysis with biomarkers response in caged clams together with factor analysis can be a useful biomonitoring tool for the identification of causal toxic pollutants and the assessment of complex metal pollutions in marine coastal environment.
authors: Key Laboratory of Urban Environment and Health, Institute of Urban Environment, Chinese Academy of Sciences, 1799 Jimei Boulevard, Xiamen City 361021, China. Electronic address: zswang@iue.ac.cn.
authors: Zaosheng
authors: Z
authors: Wang
authors: Key Laboratory of Urban Environment and Health, Institute of Urban Environment, Chinese Academy of Sciences, 1799 Jimei Boulevard, Xiamen City 361021, China. Electronic address: czyan@iue.ac.cn.
authors: Changzhou
authors: C
authors: Yan
authors: Department of Nutritional Sciences and Toxicology, University of California, 317 Morgan Hall, Berkeley, CA 94720, United States.
authors: Chris D
authors: CD
authors: Vulpe
authors: Key Laboratory of Urban Environment and Health, Institute of Urban Environment, Chinese Academy of Sciences, 1799 Jimei Boulevard, Xiamen City 361021, China.
authors: Yijun
authors: Y
authors: Yan
authors: Key Laboratory of Urban Environment and Health, Institute of Urban Environment, Chinese Academy of Sciences, 1799 Jimei Boulevard, Xiamen City 361021, China.
authors: Qiaoqiao
authors: Q
authors: Chi
mesh_terms: D000818:Animals; D061006:Bays / Q000737:chemistry; D015415:Biomarkers / Q000378:metabolism; D049872:Bivalvia / Q000187:drug effects / Q000378:metabolism*; D002374:Catalase / Q000378:metabolism; D002681:China; D004784:Environmental Monitoring / Q000379:methods*; D005979:Glutathione Peroxidase / Q000378:metabolism; D005982:Glutathione Transferase / Q000378:metabolism; D008670:Metals / Q000378:metabolism / Q000633:toxicity*; D012623:Seawater / Q000737:chemistry; D013482:Superoxide Dismutase / Q000378:metabolism
chemical_list: D015415:Biomarkers; D008670:Metals; D002374:Catalase; D005979:Glutathione Peroxidase; D013482:Superoxide Dismutase; D005982:Glutathione Transferase