title: Bullous systemic lupus erythematosus: differential diagnosis with dermatitis herpetiformis.
abstract: Bullous systemic lupus erythematosus is a rare subset of systemic lupus erythematosus that is even rarer in pediatric patients. We report a case of a 12-year-old girl who presented with a vesiculobullous eruption on her face, neck, trunk and genital and oral mucosa, as well as anemia, sterile pyuria, ANA (1:1280, speckled pattern) and positive anti-Sm and anti-RNP. Pathological examination suggested dermatitis herpetiformis, and direct immunofluorescence revealed IgG, IgA and fibrin in the epithelial basement membrane zone. We present a typical case of bullous systemic lupus erythematosus and emphasize the importance of clinical and histopathological differential diagnosis with dermatitis herpetiformis.
authors: Hospital das Clinicas, Federal University of Goias, HC – UFG, Goiania, GO, Brazil. wanessasimao@yahoo.com.br
authors: Wanessa Simão
authors: WS
authors: Barbosa
authors: Camila Martins
authors: CM
authors: Rodarte
authors: Jackeline Gomes
authors: JG
authors: Guerra
authors: Vanessa Gomes
authors: VG
authors: Maciel
authors: Luiz Fernando Fróes
authors: LF
authors: Fleury Júnior
authors: Maurício Barcelos
authors: MB
authors: Costa
mesh_terms: D002648:Child; D003874:Dermatitis Herpetiformis / Q000175:diagnosis / Q000473:pathology*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007074:Immunoglobulin G; D008180:Lupus Erythematosus, Systemic / Q000188:drug therapy / Q000473:pathology*; D012872:Skin Diseases, Vesiculobullous / Q000188:drug therapy / Q000473:pathology*
chemical_list: D007074:Immunoglobulin G