title: Functionalized 2,3-dihydrofurans via palladium-catalyzed oxyarylation of α-allyl-β-ketoesters.
abstract: The palladium-catalyzed reaction of (hetero)aryl bromides, chlorides, and nonaflates with α-allyl-β-ketoesters provides ready efficient access to functionalized 2,3-dihydrofurans. The reaction tolerates several useful substituents including chloro, fluoro, ether, ketone, ester, cyano, and nitro groups.
authors: Dipartimento di Chimica e Tecnologie del Farmaco, Sapienza, Università di Roma, P.le A. Moro 5, 00185 Roma, Italy. sandro.cacchi@uniroma1.it
authors: Sandro
authors: S
authors: Cacchi
authors: Giancarlo
authors: G
authors: Fabrizi
authors: Antonella
authors: A
authors: Goggiamani
authors: Antonia
authors: A
authors: Iazzetti
authors: David
authors: D
authors: Madec
authors: Giovanni
authors: G
authors: Poli
authors: Guillaume
authors: G
authors: Prestat
mesh_terms: D002384:Catalysis; D004952:Esters / Q000737:chemistry*; D005663:Furans / Q000138:chemical synthesis* / Q000737:chemistry; D007659:Ketones / Q000737:chemistry*; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D004952:Esters; D005663:Furans; D007659:Ketones; C073812:2,3-dihydrofuran; D010165:Palladium