title: Calcium hydroxide mixed with camphoric p-monochlorophenol or chlorhexidine in delayed tooth replantation.
abstract: This study evaluated the repair process after delayed replantation of rat teeth, using calcium hydroxide (Ca(OH)2) mixed with camphorated p-monochlorophenol (CMCP), chlorhexidine 2% (CHX), or saline as temporary root canal dressing to prevent and/or control inflammatory radicular resorption. Thirty Wistar rats (Rattus norvegicus albinos) had their right upper incisor extracted, which was bench-dried for 60 minutes. The dental papilla, the enamel organ, the dental pulp, and the periodontal ligament were removed. The teeth were immersed in 2% acidulated-phosphate sodium fluoride solution for 10 minutes. The root canals were dried with absorbent paper cones and divided into 3 groups of 10 animals according to root canal dressing used: group 1: Ca(OH)2 + saline, group 2: Ca(OH)2 + CMCP, and group 3: Ca(OH)2 + CHX 2%. Before replanting, the teeth sockets were irrigated with saline. Histological analysis revealed the presence of inflammatory resorption, replacement resorption, and ankylosis in all 3 groups. Statistical analysis showed a significant difference between group 3 and the other groups. The use of Ca(OH)2 mixed with CMCP or CHX did not show an advantage over the use of Ca(OH)2 mixed with saline in preventing and/or controlling inflammatory resorption in delayed replantation of rat teeth.
authors: Department of Surgery and Integrated Clinic, UNESP–Universidade Estadual Paulista, Dentistry School of Araçatuba, Araçatuba, São Paulo, Brazil.
authors: Carolina Lunardelli
authors: CL
authors: Trevisan
authors: Sônia Regina
authors: SR
authors: Panzarini
authors: Daniela Atili
authors: DA
authors: Brandini
authors: Wilson Roberto
authors: WR
authors: Poi
authors: Eloá Rodrigues
authors: ER
authors: Luvizuto
authors: Cláudia Letícia Vendrame
authors: CL
authors: Dos Santos
authors: Célia Tomiko Hamada Matida
authors: CT
authors: Saito
mesh_terms: D000704:Analysis of Variance; D000818:Animals; D002126:Calcium Hydroxide / Q000494:pharmacology*; D002164:Camphor / Q000494:pharmacology*; D002710:Chlorhexidine / Q000494:pharmacology*; D002733:Chlorophenols / Q000494:pharmacology*; D004338:Drug Combinations; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D012387:Root Canal Filling Materials / Q000494:pharmacology*; D012388:Root Canal Irrigants / Q000494:pharmacology*; D012390:Root Canal Therapy / Q000379:methods*; D012965:Sodium Chloride / Q000494:pharmacology; D014090:Tooth Replantation
chemical_list: D002733:Chlorophenols; D004338:Drug Combinations; D012387:Root Canal Filling Materials; D012388:Root Canal Irrigants; D012965:Sodium Chloride; D002164:Camphor; C029804:camphorated parachlorophenol; D002126:Calcium Hydroxide; D002710:Chlorhexidine