title: MAOS and medicinal chemistry: some important examples from the last years.
abstract: This review aims to highlight microwave-assisted organic synthesis as applied to medicinal chemistry in the last years, showing some reactions performed under microwave irradiation for the synthesis of distinct structurally molecules of biological interest, divided into the following groups: antineoplastics, anti-inflammatory, antimicrobial agents, antivirals, agents for the treatment of neglected diseases and central nervous system-acting prototypes.
authors: Laboratório de Avaliação e Síntese de substâncias Bioativas (LASSBio), Universidade Federal do Rio de Janeiro, Brazil.
authors: Nailton M
authors: NM
authors: Nascimento-Júnior
authors: Arthur E
authors: AE
authors: Kümmerle
authors: Eliezer J
authors: EJ
authors: Barreiro
authors: Carlos A M
authors: CA
authors: Fraga
mesh_terms: D000818:Animals; D000890:Anti-Infective Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000627:therapeutic use; D000893:Anti-Inflammatory Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000627:therapeutic use; D000970:Antineoplastic Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000627:therapeutic use; D000998:Antiviral Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000627:therapeutic use; D002493:Central Nervous System Diseases / Q000188:drug therapy; D060326:Chemistry Techniques, Synthetic / Q000379:methods*; D002626:Chemistry, Pharmaceutical; D020650:Combinatorial Chemistry Techniques / Q000379:methods*; D006571:Heterocyclic Compounds / Q000138:chemical synthesis / Q000737:chemistry / Q000627:therapeutic use; D006801:Humans; D008872:Microwaves; D015394:Molecular Structure; D058069:Neglected Diseases / Q000188:drug therapy; D010272:Parasitic Diseases / Q000188:drug therapy
chemical_list: D000890:Anti-Infective Agents; D000893:Anti-Inflammatory Agents; D000970:Antineoplastic Agents; D000998:Antiviral Agents; D006571:Heterocyclic Compounds