title: C-N bond cleavage of allylic amines via hydrogen bond activation with alcohol solvents in Pd-catalyzed allylic alkylation of carbonyl compounds.
abstract: Hydrogen-bond-activated C-N bond cleavage of allylic amines was realized in Pd-catalyzed allylic alkylation to form the C-C bond product. The method could be expanded to a series of allylic amines and carbonyl compounds with excellent results. It provides a new and convenient access to C-C bond formation based on Pd-catalyzed allylic alkylation of allylic amines by using only inexpensive alcohol solvents.
authors: School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai 200240, PR China.
authors: Xiaohu
authors: X
authors: Zhao
authors: Delong
authors: D
authors: Liu
authors: Hui
authors: H
authors: Guo
authors: Yangang
authors: Y
authors: Liu
authors: Wanbin
authors: W
authors: Zhang
mesh_terms: D000438:Alcohols / Q000737:chemistry*; D000478:Alkylation; D000498:Allyl Compounds / Q000737:chemistry*; D000588:Amines / Q000737:chemistry*; D002384:Catalysis; D006860:Hydrogen Bonding; D010165:Palladium / Q000737:chemistry*
chemical_list: D000438:Alcohols; D000498:Allyl Compounds; D000588:Amines; D010165:Palladium