title: A case of rectal cancer arising from long-standing prolapsed mucosa of the rectum.
abstract: Mucosal prolapse syndrome (MPS) has been recognized as a chronic benign inflammatory disorder, characterized mainly by rectal mucosal prolapse. Disorders representing this condition include solitary rectal ulcer syndrome (SRUS), rectal prolapse, proctitis cystica profunda, and inflammatory cap polyps. The gross appearance of rectal MPS can be occasionally misinterpreted as rectal cancer. In contrast, there have been a few reports of colorectal cancer originating from prolapsed mucosa. Herein, we report a case of MPS associated with two independent rectal cancers extending into the submucosal layer. We speculate that long-standing MPS may increase the risk of malignant transformation.
authors: Gastroenterology Division, Yokohama City University School of Medicine, Japan.
authors: Takashi
authors: T
authors: Nonaka
authors: Masahiko
authors: M
authors: Inamori
authors: Tadaomi
authors: T
authors: Kessoku
authors: Yuji
authors: Y
authors: Ogawa
authors: Shogo
authors: S
authors: Yanagisawa
authors: Tadahiko
authors: T
authors: Shiba
authors: Takashi
authors: T
authors: Sakaguchi
authors: Eiji
authors: E
authors: Gotoh
authors: Shin
authors: S
authors: Maeda
authors: Atsushi
authors: A
authors: Nakajima
authors: Kazuhiro
authors: K
authors: Atsukawa
authors: Hisao
authors: H
authors: Takahasi
authors: Yoshikiyo
authors: Y
authors: Akasaka
mesh_terms: D000368:Aged; D006801:Humans; D007413:Intestinal Mucosa / Q000473:pathology* / Q000601:surgery; D008297:Male; D012004:Rectal Neoplasms / Q000175:diagnosis* / Q000209:etiology* / Q000601:surgery; D012005:Rectal Prolapse / Q000150:complications* / Q000175:diagnosis* / Q000601:surgery