title: Male infertility and its causes in human.
abstract: Infertility is one of the most serious social problems facing advanced nations. In general, approximate half of all cases of infertility are caused by factors related to the male partner. To date, various treatments have been developed for male infertility and are steadily producing results. However, there is no effective treatment for patients with nonobstructive azoospermia, in which there is an absence of mature sperm in the testes. Although evidence suggests that many patients with male infertility have a genetic predisposition to the condition, the cause has not been elucidated in the vast majority of cases. This paper discusses the environmental factors considered likely to be involved in male infertility and the genes that have been clearly shown to be involved in male infertility in humans, including our recent findings.
authors: Department of Obstetrics and Gynecology, Asahikawa Medical University, Midorigaokahigashi 2-1-1-1, Asahikawa, Hokkaido 078-8510, Japan.
authors: Toshinobu
authors: T
authors: Miyamoto
authors: Akira
authors: A
authors: Tsujimura
authors: Yasushi
authors: Y
authors: Miyagawa
authors: Eitetsu
authors: E
authors: Koh
authors: Mikio
authors: M
authors: Namiki
authors: Kazuo
authors: K
authors: Sengoku