title: A facile approach for the delivery of inorganic nanoparticles into the brain by passing through the blood-brain barrier (BBB).
abstract: This study provides an easy and simple method to obtain inorganic nanoparticles that can penetrate the blood-brain barrier, the heavily guarded system in the brain, via cross-linked serum albumin surface coatings. Their intact BBB permeability was confirmed in both in vitro and in vivo tests.
authors: Department of Pharmacology, Yonsei University, College of Medicine, Seoul 120-752, Korea.
authors: Yeong Shin
authors: YS
authors: Yim
authors: Jin-sil
authors: JS
authors: Choi
authors: Gun Tae
authors: GT
authors: Kim
authors: Chul Hoon
authors: CH
authors: Kim
authors: Tae-Hyun
authors: TH
authors: Shin
authors: Dong Goo
authors: DG
authors: Kim
authors: Jinwoo
authors: J
authors: Cheon
mesh_terms: D000818:Animals; D001253:Astrocytes / Q000378:metabolism; D001692:Biological Transport; D001812:Blood-Brain Barrier / Q000378:metabolism*; D042783:Endothelial Cells / Q000378:metabolism; D005290:Ferric Compounds / Q000737:chemistry* / Q000378:metabolism*; D051379:Mice; D053758:Nanoparticles / Q000737:chemistry*; D009474:Neurons / Q000378:metabolism; D010539:Permeability; D012709:Serum Albumin / Q000737:chemistry* / Q000378:metabolism*
chemical_list: D005290:Ferric Compounds; D012709:Serum Albumin; C001215:ferrite