title: Ocular melanoma: Keep your eyes open for late brain metastases.
abstract: BACKGROUND
  The most frequent intraocular malignant tumor is choroidal melanoma (CM). Although brain metastasis is a common feature of other types of cancers, metastasis of CM to the brain is a rare entity.
  
  
  METHODS
  The authors report a case of a 28-year-old woman presenting with a single brain metastasis, 10 years after the treatment of a CM. She underwent a total en-bloc resection of the lesion, and the diagnosis was conﬁrmed histopathologically. The patient concomitantly received whole-brain irradiation therapy combined with chemotherapy, with a survival period of 24 months.
  
  
  CONCLUSIONS
  The present case report draws attention to the necessity of a close and lifelong follow-up of patients treated for this malignancy. The international literature is also reviewed.
authors: Department of Neurosurgery, Weill Cornell Medical College, New York, USA.
authors: Danilo O
authors: DO
authors: de A Silva
authors: Georgios K
authors: GK
authors: Matis
authors: Leonardo F
authors: LF
authors: Costa
authors: Matheus A P
authors: MA
authors: Kitamura
authors: Eduardo V
authors: EV
authors: de C Júnior
authors: Breno J A P
authors: BJ
authors: Barbosa
authors: Isaac B
authors: IB
authors: Santiago
authors: Tatiane I
authors: TI
authors: Silva
authors: Fabiana Q
authors: FQ
authors: de P A Silva
authors: Carlos U
authors: CU
authors: Pereira
authors: Hildo R C
authors: HR
authors: Azevedo Filho