title: Primary angiitis of the central nervous system: a case report.
abstract: Primary angiitis of the central nervous system is a rare and difficult entity. Here we represented the clinical and pathological features of a patient with little response to steroid before definite diagnosis. The 50-year-old male had a fluctuating disease course for more than 3 years. He presented visual disorders, seizure, cognitive impairment, hypersomnia, unsteady gait, dysphasia, dysphagia, and incontinence. Magnetic resonance imaging showed multiple, supratentorial and infratentorial abnormal signals, while cerebrospinal fluid and cerebral angiography were normal. Magnetic resonance spectrum showed a decrease of N-acetyl-aspartate. Brain biopsy revealed nongranulomatous lymphatic vasculitis with reactive gliosis, cicatrization, demyelination and focal hemorrhages.
authors: Department of Geriatrics, Qilu Hospital of Shandong University, Jinan, Shandong 250012, China.
authors: Xiao-lin
authors: XL
authors: Yu
authors: Ai-fen
authors: AF
authors: Liu
authors: Lin
authors: L
authors: Ma
authors: Chuan-zhu
authors: CZ
authors: Yan
authors: Yu-ying
authors: YY
authors: Zhao
authors: Pei-yan
authors: PY
authors: Shan
mesh_terms: D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D020293:Vasculitis, Central Nervous System / Q000175:diagnosis*