title: Effect of antioxidant mixtures on growth and ochratoxin a production of Aspergillus section Nigri species under different water activity conditions on peanut meal extract agar.
abstract: The effect of mixtures of antioxidants butylated hydroxyanisol (BHA) and propyl paraben (PP) on lag phase, growth rate and ochratoxin A (OTA) production by four Aspergillus section Nigri strains was evaluated on peanut meal extract agar (PMEA) under different water activities (a(w)). The antioxidant mixtures used were: BHA + PP (mM), M1 (0.5 + 0.5), M2 (1.0 + 0.5), M3 (2.5 + 0.5), M4 (0.5 + 1.0), M5 (1.0 + 1.0), M6 (2.5 + 1.0), M7 (5.0 + 2.5) and M8 (10 + 2.5). The mixture M8 completely suppressed mycelial growth for all strains. A significant stimulation in OTA production was observed with mixtures M1 to M5 mainly at the highest a(w); whereas M6, M7 and M8 completely inhibited OTA production in all strains assayed; except M6 in A. carbonarius strain (RCP G). These results could enable a future intervention strategy to minimize OTA contamination.
authors: Departamento de Microbiología e Inmunología, Facultad de Ciencias Exactas, Físico-Químicas y Naturales, Universidad Nacional de Río Cuarto, Ruta Nacional Nº 36 Km 601 (5800) Río Cuarto, Córdoba, Argentina. cbarberis@exa.unrc.edu.ar
authors: Carla
authors: C
authors: Barberis
authors: Andrea
authors: A
authors: Astoreca
authors: María Guillermina
authors: MG
authors: Fernandez-Juri
authors: Ana María
authors: AM
authors: Dalcero
authors: Carina
authors: C
authors: Magnoli
mesh_terms: D000975:Antioxidants / Q000008:administration & dosage*; D010367:Arachis; D001230:Aspergillus / Q000187:drug effects* / Q000254:growth & development / Q000378:metabolism; D002084:Butylated Hydroxytoluene / Q000008:administration & dosage*; D003470:Culture Media; D004347:Drug Interactions; D005506:Food Contamination / Q000517:prevention & control; D009793:Ochratoxins / Q000378:metabolism*; D010226:Parabens / Q000008:administration & dosage*; D010936:Plant Extracts; D014867:Water
chemical_list: D000975:Antioxidants; D003470:Culture Media; D009793:Ochratoxins; D010226:Parabens; D010936:Plant Extracts; D014867:Water; C025589:ochratoxin A; D002084:Butylated Hydroxytoluene; C006068:propylparaben