title: Seizure-induced miosis.
abstract: Ictal autonomic pupillary dilation is common; however, miosis is rare. We describe a case of focal seizures secondary to cortical dysplasia presenting with bilateral pupillary miosis, rendered seizure free by resective surgery. The seizure-onset zone was localized within the left middle parietal gyrus by intracranial electrographic recording. Seizure onset was coincident with focal left centroparietal fast spike activity on electroencephalography (EEG). A large region of the left frontocentral cortical dysplasia was demonstrated on magnetic resonance imaging (MRI). Complete resection of the area of cortical dysplasia and additional cortical regions of ictal activity, identified using intracranial EEG, rendered the patient seizure free.
authors: Wessex Neurological Centre, Southampton University Hospitals NHS Trust, Southampton, United Kingdom. a.sadek@soton.ac.uk
authors: Ahmed-Ramadan
authors: AR
authors: Sadek
authors: Fenella
authors: F
authors: Kirkham
authors: Simon
authors: S
authors: Barker
authors: William P
authors: WP
authors: Gray
authors: David
authors: D
authors: Allen
mesh_terms: D004569:Electroencephalography; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D008297:Male; D054220:Malformations of Cortical Development / Q000150:complications*; D010296:Parietal Lobe / Q000473:pathology / Q000503:physiopathology; D011681:Pupil Disorders / Q000151:congenital* / Q000209:etiology; D012640:Seizures / Q000150:complications*