title: Pseudotumour cerebri in children: etiological, clinical features and treatment modalities.
abstract: To investigate the etiological and clinical features of pseudotumour cerebri (PTC) in children, features of 12 children with PTC were documented. The etiology could be clarified in 6 patients. The other 6 patients were accepted as idiopathic intracranial hypertension (primary PTC). Acetazolamide was used as the first drug and was effective in only 4 patients who had no underlying cause. Repeated lumbar punctures (LP) were performed in 6 patients and 5 of them were unresponsive. Prednisone was used in 3 patients and was effective in only one patient. The CSF pressure continued to be high in five patients and could be normalized only by withdrawing of the precipitating drug in three patients and by ventricular-peritoneal shunting in two patients with cerebral venous thrombosis. Although, medical treatment and repeated LP are usually effective in children with PTC, clarifying and solving the underlying cause can be crucial.
authors: Department of Pediatrics, Division of Child Neurology, Marmara University School of Medicine, Istanbul, Turkey. ninieldes@yahoo.com
authors: Nilufer
authors: N
authors: Hacifazlioglu Eldes
authors: Yuksel
authors: Y
authors: Yilmaz
mesh_terms: D000086:Acetazolamide / Q000627:therapeutic use; D000293:Adolescent; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D000927:Anticonvulsants / Q000627:therapeutic use; D015170:Cerebrospinal Fluid Pressure / Q000502:physiology; D002648:Child; D002675:Child, Preschool; D004172:Diplopia / Q000209:etiology; D005123:Eye / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D006261:Headache / Q000209:etiology; D006801:Humans; D007223:Infant; D018810:Magnetic Resonance Angiography; D008279:Magnetic Resonance Imaging; D008297:Male; D009460:Neurologic Examination; D010690:Phlebography; D011379:Prognosis; D011559:Pseudotumor Cerebri / Q000209:etiology* / Q000523:psychology / Q000628:therapy*; D013256:Steroids / Q000627:therapeutic use; D017287:Ventriculoperitoneal Shunt; D014792:Visual Acuity / Q000502:physiology
chemical_list: D000893:Anti-Inflammatory Agents; D000927:Anticonvulsants; D013256:Steroids; D000086:Acetazolamide