title: Isolation of a novel carotenoid, OH-chlorobactene glucoside hexadecanoate, and related rare carotenoids from Rhodococcus sp. CIP and their antioxidative activities.
abstract: In the course of screening for antioxidative carotenoids from bacteria, we isolated and identified a novel carotenoid, OH-chlorobactene glucoside hexadecanoate (4), and rare carotenoids, OH-chlorobactene glucoside (1), OH-γ-carotene glucoside (2) and OH-4-keto-γ-carotene glucoside hexadecanoate (3) from Rhodococcus sp. CIP. The singlet oxygen ((1)O(2)) quenching model of these carotenoids showed potent antioxidative activities IC(50) 14.6 µM for OH-chlorobactene glucoside hexadecanoate (4), 6.5 µM for OH-chlorobactene glucoside (1), 9.9 µM for OH-γ-carotene glucoside (2) and 7.3 µM for OH-4-keto-γ-carotene glucoside hexadecanoate (3).
authors: Department of Food and Nutrition, Japan Women's University, Tokyo, Japan.
authors: Ayako
authors: A
authors: Osawa
authors: Asami
authors: A
authors: Kasahara
authors: Shoko
authors: S
authors: Mastuoka
authors: Sören
authors: S
authors: Gassel
authors: Gerhard
authors: G
authors: Sandmann
authors: Kazutoshi
authors: K
authors: Shindo
mesh_terms: D000975:Antioxidants / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D002338:Carotenoids / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D005960:Glucosides / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D020128:Inhibitory Concentration 50; D015394:Molecular Structure; D018384:Oxidative Stress; D010168:Palmitates / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D010802:Phylogeny; D012336:RNA, Ribosomal, 16S / Q000235:genetics; D012240:Rhodococcus / Q000737:chemistry* / Q000145:classification; D026082:Singlet Oxygen / Q000737:chemistry
chemical_list: D000975:Antioxidants; D005960:Glucosides; C570731:OH-chlorobactene glucoside; C570730:OH-chlorobactene glucoside hexadecanoate; C570732:OH-gamma-carotene glucoside; D010168:Palmitates; D012336:RNA, Ribosomal, 16S; D026082:Singlet Oxygen; D002338:Carotenoids