title: Feline immunodeficiency virus: disease association versus causation in domestic and nondomestic felids.
abstract: Feline immunodeficiency virus (FIV) is an important infection in both domestic and nondomestic cats. Although many studies have provided insight into FIV pathophysiology and immunologic responses to infection in cats, questions remain regarding the association of FIV with specific disease syndromes. For many diseases, both association and causation of disease with FIV remain to be confirmed and clarified. The use of experimental infection models is unlikely to yield answers about naturally infected domestic cats and is not feasible in nondomestic felids, many of which are endangered species. Researches might consider further study of naturally occurring disease with an emphasis on confirming which diseases have a likely association with FIV.
authors: Institute of Veterinary, Animal, and Biomedical Sciences, Massey University, Tennent Drive, Palmerston North 4412, New Zealand. J.White@massey.ac.nz
authors: Joanna
authors: J
authors: White
authors: Alison
authors: A
authors: Stickney
authors: Jacqueline M
authors: JM
authors: Norris
mesh_terms: D000818:Animals; D000829:Animals, Domestic / Q000821:virology; D000835:Animals, Wild / Q000821:virology; D002415:Cats; D016181:Feline Acquired Immunodeficiency Syndrome / Q000175:diagnosis / Q000453:epidemiology / Q000635:transmission / Q000821:virology*; D016089:Immunodeficiency Virus, Feline / Q000472:pathogenicity*; D018571:Sentinel Surveillance / Q000662:veterinary