title: Successful long-term treatment with pemetrexed of NSCLC associated with EML4-ALK and low thymidylate synthase expression.
authors: Department of Medical Oncology, Kinki University Faculty of Medicine, Osaka-Sayama, Osaka, Japan. chi-okamoto@dotd.med.kindai.ac.jp
authors: Masayuki
authors: M
authors: Takeda
authors: Isamu
authors: I
authors: Okamoto
authors: Kazuko
authors: K
authors: Sakai
authors: Kaoru
authors: K
authors: Tanaka
authors: Masaaki
authors: M
authors: Terashima
authors: Kazuto
authors: K
authors: Nishio
authors: Kazuhiko
authors: K
authors: Nakagawa
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy / Q000235:genetics / Q000556:secondary; D002289:Carcinoma, Non-Small-Cell Lung / Q000188:drug therapy* / Q000235:genetics / Q000556:secondary; D018279:Carcinoma, Signet Ring Cell / Q000188:drug therapy / Q000235:genetics / Q000556:secondary; D005260:Female; D005971:Glutamates; D006147:Guanine / Q000031:analogs & derivatives; D006801:Humans; D007124:Immunoenzyme Techniques; D008175:Lung Neoplasms / Q000188:drug therapy* / Q000235:genetics / Q000473:pathology; D008875:Middle Aged; D015514:Oncogene Proteins, Fusion / Q000235:genetics*; D000068437:Pemetrexed; D010997:Pleural Neoplasms / Q000188:drug therapy / Q000235:genetics / Q000556:secondary; D011379:Prognosis; D013940:Thymidylate Synthase / Q000378:metabolism*; D013997:Time Factors
chemical_list: C522504:EML4-ALK fusion protein, human; D005971:Glutamates; D015514:Oncogene Proteins, Fusion; D000068437:Pemetrexed; D006147:Guanine; D013940:Thymidylate Synthase