title: Effect of dentifrices against hydrochloric acid-induced erosion.
abstract: OBJECTIVE
  This in vitro investigation assessed whether different dentifrices would be capable of controlling the enamel erosion progression caused by HCl.
  
  
  METHODS
  Sixty bovine enamel slabs were covered with acid-resistant varnish, except for a 2.5-mm2 circular area on the labial surface. According to a complete block design, the experimental units were immersed in HCl solution (pH 1.2; 0.1M). After storage in artificial saliva for 1 h, specimens (n = 15) were exposed to different dentifrices: Sensodyne Cool Gel (1100 ppm F), Sensodyne ProNamel (1450 ppm F), and PrevDent 5000 (5000 ppm F). The control group was immersed in deionised water. Following five cycles of erosive challenge, the slabs were prepared for porosity evaluation using solutions of copper sulfate and rubeanic acid.
  
  
  RESULTS
  ANOVA demonstrated no difference in the enamel porosity as a function of the dentifrice employed (P = 0.5494).
  
  
  CONCLUSIONS
  The damage caused by a simulated intrinsic erosive challenge seems unable to be controlled by fluoridated dentifrices, even when this ion is found in elevated concentrations.
authors: University of Ribeirao Preto, Ribeirao Preto, Brazil. danimessias@gmail.com
authors: Danielle Cristine
authors: DC
authors: Messias
authors: Fernando Akio
authors: FA
authors: Maeda
authors: Cecilia Pedroso
authors: CP
authors: Turssi
authors: Mônica Campos
authors: MC
authors: Serra
mesh_terms: D000818:Animals; D002327:Cariostatic Agents / Q000627:therapeutic use; D002417:Cattle; D004396:Coloring Agents; D019327:Copper Sulfate; D003743:Dental Enamel / Q000187:drug effects; D003745:Dental Enamel Permeability / Q000187:drug effects; D003802:Dentifrices / Q000627:therapeutic use*; D018450:Disease Progression; D006851:Hydrochloric Acid / Q000009:adverse effects*; D006863:Hydrogen-Ion Concentration; D007101:Immersion; D008422:Materials Testing; D016062:Porosity; D011897:Random Allocation; D012464:Saliva, Artificial / Q000737:chemistry; D012969:Sodium Fluoride / Q000627:therapeutic use; D013854:Thioamides; D013997:Time Factors; D014077:Tooth Erosion / Q000139:chemically induced / Q000517:prevention & control*
chemical_list: D002327:Cariostatic Agents; D004396:Coloring Agents; D003802:Dentifrices; D012464:Saliva, Artificial; D013854:Thioamides; D012969:Sodium Fluoride; C005728:rubeanic acid; D019327:Copper Sulfate; D006851:Hydrochloric Acid