title: [Frontiers in vitamin D; basic research and clinical application. Activated vitamin D in psoriasis].
abstract: Psoriasis is a chronic immune-mediated disease that appears on the skin. It occurs when the immune system sends out faulty signals that speed up the growth cycle of skin cells. Psoriasis is typically a lifelong condition. There is currently no cure, but various treatments can help to control the symptoms. Activated vitamin D3 is the first-line treatment for psoriasis. Psoriasis is often treated with combination therapy of activated vitamin D3 and other treatment. Depending on the severity and location of outbreaks, individuals may experience significant physical discomfort and some disability. Thus, the goal for the treatment of psoriasis is to control the signs and symptoms over a long period and to ameliorate the quality of life of psoriasis patients.
authors: Geriatric Medicine, Kanazawa Medical University, Japan.
authors: Masashi
authors: M
authors: Okuro
authors: Shigeto
authors: S
authors: Morimoto
mesh_terms: D000287:Administration, Topical; D002762:Cholecalciferol / Q000008:administration & dosage* / Q000009:adverse effects / Q000494:pharmacology; D002990:Clobetasol / Q000008:administration & dosage; D003713:Dendritic Cells; D004359:Drug Therapy, Combination; D006801:Humans; D053759:Interleukin-23; D052247:Nitric Oxide Synthase Type II; D011565:Psoriasis / Q000188:drug therapy* / Q000276:immunology; D011788:Quality of Life; D012176:Retinoids / Q000008:administration & dosage; D058504:Th17 Cells; D014409:Tumor Necrosis Factor-alpha
chemical_list: D053759:Interleukin-23; D012176:Retinoids; D014409:Tumor Necrosis Factor-alpha; D002762:Cholecalciferol; D002990:Clobetasol; D052247:Nitric Oxide Synthase Type II