title: A spatial resolution study of a new optical tomography-based polymer gel dosimetry system.
abstract: A spatial resolution investigation of the OCTOPUSTM-IQ scanner in combination with the new BANG3-Pro2(r) polymer gel was performed by scanning a high-contrast needle phantom. The phantom contained five thin needles (0.3_mm diameter) embedded in gel positioned in different patterns: needles were inserted (a) at 45° angle from the center of the gel container, and (b) vertically along the gel axis. The non-irradiated needle phantoms were scanned at various slice spacings (0.25-1.0_mm) and for two different laser beam orientations. Optical density profiles and their full width at half maximum (FWHM) were evaluated for resolution limit. The modulation transfer function (MTF) corresponding to measured point spread function (PSF) data was calculated. With high resolution scanning mode and 0.25_mm pixel resolution, the measured PSFs at the center of the gel dosimeter have a FWHM of 0.95_mm. The MTF for the 0.25_mm reconstruction pixel size suggests that the resolution of the system is 0.5_mm or less. We also observed a progressive degradation of the vertical needle images with off-axis distance, attributable to the defocusing of the laser beam. No significant degradation was observed up to the maximum useful reconstructed image radius of 50_mm from the gel dosimeter center axis.
authors: Department of Radiation Physics, M. D. Anderson Cancer Center Orlando, 1400 S. Orange Ave., Orlando, FL 32806, USA.
authors: S I
authors: SI
authors: Sriprisan
authors: O
authors: O
authors: Lopatiuk-Tirpak
authors: S L
authors: SL
authors: Meeks
authors: O A
authors: OA
authors: Zeidan
mesh_terms: D005782:Gels; D006801:Humans; D021621:Imaging, Three-Dimensional; D019047:Phantoms, Imaging; D011108:Polymers / Q000737:chemistry*; D011874:Radiometry / Q000295:instrumentation* / Q000379:methods*; D041622:Tomography, Optical
chemical_list: D005782:Gels; D011108:Polymers