title: Organ-sparing surgery for penile cancer: complications and outcomes.
abstract: OBJECTIVE
  To evaluate the complications and outcomes of organ-sparing surgery in penile cancer.
  
  
  METHODS
  Thirty-two penile cancer patients had undergone organ-sparing surgery between 2006 and 2010 in Fudan University Shanghai Cancer Center. Applied surgical techniques included radical circumcision and/or wide local excision. Intraoperative frozen section analyses of circumference and deep margins were performed to guarantee complete removal of cancerous tissue. Complications and oncological and functional outcomes were recorded prospectively. Bilateral inguinal lymphadenectomy was routinely performed in patients with invasive penile cancer.
  
  
  RESULTS
  Of 32 patients, 8 underwent radical circumcision, 18 were treated with wide local excision, and 6 received wide local excision and circumcision. Postoperatively, only 3 (9.4%) patients had minor complications. With a median follow-up of 26.5 months, local control was achieved in 29 (90.6%) patients, and 3 patients (9.4%) with positive lymph nodes died of disseminated disease. Of 29 patients who completed follow-up surveys of functional outcome, only 1 (4.5%) claimed decreased sexual function and all reported satisfied urination.
  
  
  CONCLUSIONS
  Organ-sparing surgery, such as radical circumcision and wide local excision is an appropriate treatment option for selected penile cancer patients. It preserves sexual and urination function without significantly increasing the risk of recurrence.
authors: Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.
authors: Jian
authors: J
authors: Li
authors: Yao
authors: Y
authors: Zhu
authors: Shi-Lin
authors: SL
authors: Zhang
authors: Chao-Fu
authors: CF
authors: Wang
authors: Xu-Dong
authors: XD
authors: Yao
authors: Bo
authors: B
authors: Dai
authors: Ding-Wei
authors: DW
authors: Ye
mesh_terms: D000328:Adult; D000368:Aged; D006801:Humans; D008297:Male; D008875:Middle Aged; D010412:Penile Neoplasms / Q000601:surgery*; D011446:Prospective Studies; D016896:Treatment Outcome; D013521:Urologic Surgical Procedures, Male / Q000009:adverse effects / Q000379:methods; D055815:Young Adult