title: [Chemical constituents of Carya cathayensis and their antitumor bioactivity].
abstract: OBJECTIVE
  To investigate the chemical constituents of Carya cathayensis and their antitumor bioactivity.
  
  
  METHODS
  The compounds were isolated by Sephadex LH-20 and silica gel column chromatography. Their structures were identified by physicochemical properties and spectroscopic analysis. Then their cytotoxic activity was studied.
  
  
  RESULTS
  Five compounds were elucidated as chrysophanol (1), physcion (2), beta-sitosterol (3), pinostrobin(4), 4,8-dihydroxy-1-tetralone (5).
  
  
  CONCLUSIONS
  Compounds 2 and 5 are isolated from Carya cathayensis for the first time. In the MTT antitumor experiments, the compounds 1,4 and 5 have the cytotoxic activity to KB cell.
authors: College of Pharmaceutical Sciences of Anhui University of Traditional Chinese Medicine, Hefei 230031, China. dlwu7375@sina.com
authors: De-lin
authors: DL
authors: Wu
authors: Shi-yun
authors: SY
authors: Chen
authors: Jing-song
authors: JS
authors: Liu
authors: Chuan-shan
authors: CS
authors: Jin
authors: Feng-qing
authors: FQ
authors: Xu
mesh_terms: D000880:Anthraquinones / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D031325:Carya / Q000737:chemistry*; D002470:Cell Survival / Q000187:drug effects; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D004642:Emodin / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification; D044950:Flavanones / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D005638:Fruit / Q000737:chemistry; D056945:Hep G2 Cells; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D024301:Plant Bark / Q000737:chemistry; D044024:Tetralones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: D000880:Anthraquinones; D004365:Drugs, Chinese Herbal; D044950:Flavanones; D044024:Tetralones; C008905:physcione; D004642:Emodin; C027113:chrysophanic acid; C411294:pinostrobin