title: [Pulmonary aspergillosis and HIV infection: about two cases].
abstract: The occurrence of invasive pulmonary aspergillosis is unusual during the course of AIDS. Patients at risk have a CD4 T-lymphocyte count under 50 cells/mm(3) combined with other risk factors in 50% of the cases. Positive diagnosis is based on chest CT scan imaging and isolation of Aspergillus in broncho-alveolar fluid. Detection of galactomannan antigen in serum and broncho-alveolar lavage fluid (BALF) is a reliable complementary tool in assessing the diagnosis. The first line therapy is Voriconazole. The prognosis, often severe, depends on prompt initiation of the appropriate antifungal treatment. We report two cases of invasive pulmonary aspergillosis in AIDS patients.
authors: Service des maladies infectieuses, CHU Ibn Rochd, quartier des hôpitaux, Casablanca 20100, Maroc. elfanemouna@gmail.com
authors: M
authors: M
authors: El Fane
authors: A
authors: A
authors: Ouladlahsen
authors: A
authors: A
authors: Bakhatar
authors: M
authors: M
authors: Sodqi
authors: K Marhoum
authors: KM
authors: El Filali
authors: A
authors: A
authors: Bahlaoui
authors: A
authors: A
authors: Chakib
mesh_terms: D000328:Adult; D000935:Antifungal Agents / Q000627:therapeutic use*; D001228:Aspergillosis / Q000175:diagnosis* / Q000000981:diagnostic imaging; D018893:Bronchoalveolar Lavage; D015658:HIV Infections / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D008172:Lung Diseases, Fungal / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D055732:Pulmonary Aspergillosis / Q000150:complications* / Q000175:diagnosis; D011743:Pyrimidines / Q000627:therapeutic use*; D011859:Radiography; D012307:Risk Factors; D014230:Triazoles / Q000627:therapeutic use*; D065819:Voriconazole
chemical_list: D000935:Antifungal Agents; D011743:Pyrimidines; D014230:Triazoles; D065819:Voriconazole