title: Variant angina associated with coronary artery endothelial dysfunction and myocardial bridge: a case report and review of the literature.
abstract: The association of variant angina (VA) and myocardial bridges is a rare finding. We describe a case of VA with recurrent coronary spasm triggered by different stimuli at the site of a myocardial bridge. The interplay of endothelial dysfunction, coronary vasoconstriction and myocardial bridging was detected by intracoronary acetylcholine test and IVUS. We speculate that mechanical stimulation at the bridge site caused endothelial dysfunction and enhanced local susceptibility to vasoconstrictor stimuli. Variant angina should always be suspected in cases of ST-elevation acute coronary syndrome without any significant angiographic coronary stenosis.
authors: Department of Cardiology, Ospedale Castelli, Italy.
authors: Federico
authors: F
authors: Nardi
authors: Edoardo
authors: E
authors: Verna
authors: Gioel Gabrio
authors: GG
authors: Secco
authors: Andrea
authors: A
authors: Rognoni
authors: Angelo
authors: A
authors: Sante Bongo
authors: Gabriele
authors: G
authors: Iraghi
authors: Stefano
authors: S
authors: Bertuol
authors: Alessandro
authors: A
authors: Lupi
mesh_terms: D000328:Adult; D000788:Angina Pectoris, Variant / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology; D003331:Coronary Vessels / Q000473:pathology*; D004730:Endothelium, Vascular / Q000473:pathology*; D006801:Humans; D008297:Male; D054084:Myocardial Bridging / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology