title: Organ weights, muscle composition and fatty acid profiles in lambs fed salbutamol: Effect of a 5-day withdrawal period.
abstract: Lambs were fed ad libitum on a diet containing the β-adrenergic agonist salbutamol (2 ppm) for 38 days to investigate its effects on organ weights, muscle composition and fatty acid profiles. The influence of a 5-day withdrawal period was also assessed. The oral administration of salbutamol did not increase muscle weights and no differences were found in liver, heart and lung proportions. However, kidney weight was higher in the salbutamol-not-withdrawn animals. In treated animals fat and collagen levels decreased (P < 0.05), while protein increased (P < 0.05) in the semitendinosus (ST) muscle when compared to controls. However, no effects of the β-agonist treatment were found in the longissimus dorsi (LD) muscle. Intramuscular LD polyunsaturated fatty acids were higher (P < 0.05). Subcutaneous adipose tissue samples were higher (P < 0.05) in total unsaturated fatty acids and lower (P < 0.05) in total saturated fatty acids. All these changes in the fatty acid profiles of both intramuscular and adipose tissues were more marked after the 5-day salbutamol withdrawal period.
authors: Department of Food Technology and Toxicology, University of Navarra, Irunlarrea s/n, Pamplona 31008, Navarra, Spain.
authors: E
authors: E
authors: Sota
authors: A S
authors: AS
authors: Del Barrio
authors: M A
authors: MA
authors: Garcia-Calonge
authors: M P
authors: MP
authors: Portillo
authors: I
authors: I
authors: Astiasarán
authors: J A
authors: JA
authors: Martinez