title: Deep venous thrombosis in acute stroke patients.
abstract: Deep venous thrombosis (DVT) is a complication of stroke. Our aim was to determine the frequency of DVT in patients with acute stroke, risk factors for its development, and its influence on the 3-month outcome. A total of 323 consecutive patients with acute stroke were enrolled. We performed ultrasound imaging within 7 days after stroke. Deep venous thrombosis was found in 8.7% of patients, only in those with ischemic stroke. Patients with DVT were more frequently female (71.4% vs 49.5%), had prestroke Modified Rankin scale (mRS) 3 to 5 (42.9% vs 15.3%), elevated C-reactive protein (CRP) serum level (65.4% vs 32.5%), and a trend toward elevated serum fibrinogen level (85.7% vs 70.1%; P = .08). In a multivariate analysis, elevated CRP (odds ratio [OR] 3.15) and prestroke disability (OR 2.89) were independent risk factors for DVT. Deep venous thrombosis occurs in <10% of patients with acute stroke and does not significantly affect the 3-month outcome. Prestroke dependency and elevated CRP level at baseline are independent risk factors for DVT.
authors: Second Department of Neurology, Institute of Psychiatry and Neurology, Warsaw, Poland. jbembenek@o2.pl
authors: Jan P
authors: JP
authors: Bembenek
authors: Michał
authors: M
authors: Karlinski
authors: Adam
authors: A
authors: Kobayashi
authors: Anna
authors: A
authors: Czlonkowska
mesh_terms: D000208:Acute Disease; D000368:Aged; D000369:Aged, 80 and over; D002545:Brain Ischemia / Q000097:blood / Q000150:complications / Q000453:epidemiology; D002097:C-Reactive Protein / Q000378:metabolism; D005260:Female; D005340:Fibrinogen / Q000378:metabolism; D006801:Humans; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D012737:Sex Factors; D020521:Stroke / Q000097:blood / Q000150:complications / Q000453:epidemiology*; D013997:Time Factors; D020246:Venous Thrombosis / Q000097:blood / Q000453:epidemiology* / Q000209:etiology
chemical_list: D005340:Fibrinogen; D002097:C-Reactive Protein