title: [A prospective clinical study on autologous periosteum wrapping tendon allograft for anterior cruciate ligament reconstruction].
abstract: OBJECTIVE
  To study the effectiveness of anterior cruciate ligament (ACL) reconstruction using autologous periosteum wrapping tendon allograft by comparing with using simple tendon allograft.
  
  
  METHODS
  Between March 2008 and November 2008, 68 patients with ACL injury were treated, who were in accordance with the inclusion criteria. They were divided into 2 groups randomly according to different treatment methods: ACL was reconstructed with autologous periosteum wrapping tendon allograft in 31 patients (test group) and with simple tendon allograft (control group) in 37 patients. There was no significant difference in gender, age, disease duration, the cause of injury, and functional score preoperatively between 2 groups (P > 0.05). Anatomic single-bundle ACL reconstruction was performed in 2 groups.
  
  
  RESULTS
  Little exudation at tibial tunnel incision was found in 1 case respectively in both groups at 2 weeks after operation and was cured by dressing change and antibiotics. The other incisions healed by first intention. The patients were followed up 24-29 months (mean, 26 months) in the test group and 24-32 months (mean, 27 months) in the control group. CT showed bone tunnel enlargement in both groups at 2 years after operation, but the rate of the tunnel enlargement was less in the test group (5/31, 16.1%) than in the control group (14/37, 37.8%), showing significant difference (chi2 = 3.948, P = 0.047). At 2 years after operation, the results of Lachman test and pivot shift test were negative in 23 cases (74.2%) and 25 cases (80.6%) of the test group, and in 26 cases (70.3%) and 30 cases (81.1%) of the control group, respectively. KT-1000 examination showed the displacement of the test group [(1.74 +/- 0.88) mm] was less than that of the control group [(2.36 +/- 0.83) mm], showing significant difference (t = -2.979, P = 0.004). There was no significant difference in Lysholm score, Hospital for Special Surgery (HSS) score, Tegner score, and International Knee Documentation Committee (IKDC) score between 2 groups at 2 years after operation (P > 0.05).
  
  
  CONCLUSIONS
  Compared with simple tendon allograft, ACL reconstruction with autologous periosteum wrapping tendon allograft can improve tendon-bone healing, and decrease the rate of bone tunnel enlargement, so it has good short-term outcome.
authors: Department of Joint Surgery, Hospital of Hebei Medical University, Shijiazhuang Hebei 050051, PR China.
authors: Zhihui
authors: Z
authors: Wang
authors: Baicheng
authors: B
authors: Chen
authors: Xiaoyang
authors: X
authors: Zhang
authors: Ran
authors: R
authors: Sun
authors: Hu
authors: H
authors: Liu
authors: Lei
authors: L
authors: Xie
authors: Chaohua
authors: C
authors: Zhu
mesh_terms: D000328:Adult; D016118:Anterior Cruciate Ligament / Q000601:surgery; D059549:Anterior Cruciate Ligament Reconstruction / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010521:Periosteum / Q000637:transplantation*; D011446:Prospective Studies; D013710:Tendons / Q000637:transplantation*; D014182:Transplantation, Autologous; D055815:Young Adult