title: Graves'-like orbitopathy in a patient with chronic autoimmune pancreatitis.
abstract: BACKGROUND
  Graves' orbitopathy is an inflammatory orbital disease that represents the commonest extrathyroidal manifestation of Graves' disease. Autoimmune pancreatitis (AIP) is a rare inflammatory disease characterized by prominent lymphocytic infiltration and fibrosis of the pancreas causing organ dysfunction.
  
  
  CONCLUSIONS
  This report provides the first clinical description of severe Graves'-like orbitopathy occurring in association with AIP. Although there was no clear evidence of autoimmune thyroid disease or dysfunction in our patient, the clinical course of his orbitopathy was related to that of AIP, the relapses of orbital inflammation being temporally coincident.
  
  
  CONCLUSIONS
  Our data suggest that shared autoantigens between the pancreas and the orbit might be responsible for the unusual disorder observed in our patient.
authors: Unit of Internal Medicine and Endocrinology, University of Pavia, Pavia, Italy.
authors: Rodolfo
authors: R
authors: Fonte
authors: Barbara
authors: B
authors: Pirali
authors: Vitantonio
authors: V
authors: Caramia
authors: Rosa
authors: R
authors: Dionisio
authors: Sara
authors: S
authors: Lodigiani
authors: Luisella
authors: L
authors: Sibilla
authors: Mario
authors: M
authors: Rotondi
authors: Luca
authors: L
authors: Chiovato
mesh_terms: D000305:Adrenal Cortex Hormones / Q000008:administration & dosage; D001324:Autoantigens / Q000276:immunology; D001327:Autoimmune Diseases / Q000150:complications* / Q000175:diagnosis / Q000276:immunology / Q000628:therapy; D015551:Autoimmunity; D049970:Graves Ophthalmopathy / Q000175:diagnosis / Q000209:etiology* / Q000276:immunology / Q000628:therapy; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D050500:Pancreatitis, Chronic / Q000150:complications* / Q000175:diagnosis / Q000276:immunology / Q000628:therapy; D020551:Pulse Therapy, Drug; D012720:Severity of Illness Index; D016896:Treatment Outcome
chemical_list: D000305:Adrenal Cortex Hormones; D001324:Autoantigens