title: The use of bevacizumab in a multilevel retinal hemorrhage secondary to retinal macroaneurysm: a 39-month follow-up case report.
abstract: OBJECTIVE
  The evaluation of long-term visual outcome after the use of bevacizumab for the management of multilevel hemorrhage due to retinal arterial macroaneurysm (MA).
  
  
  METHODS
  A 71-year-old hypertensive female presented with sudden reduction of visual acuity in her left eye (OS). Fundoscopy revealed an arterial macroaneurysm with preretinal and subretinal hemorrhage in the eye. Due to significant macular involvement, the patient received two intravitreal injections of bevacizumab within 2 months.
  
  
  RESULTS
  Significant visual and anatomical recovery was observed 2 months later, which was confirmed by fluorescein angiography. At the end of a follow-up period (39 months) visual acuity and visual field were at normal levels.
  
  
  CONCLUSIONS
  Retinal MA is a relatively rare condition. Anti-vascular endothelial growth factor therapy appears a safe and effective treatment option for selected symptomatic individuals that may offer faster visual rehabilitation. Herein we report, for the first time, a 39-month follow-up of a retinal MA treated with anti-vascular endothelial growth factor therapy.
authors: 2nd University Department of Ophthalmology, Papageorgiou Hospital, Thessaloniki, Greece.
authors: Dimitrios
authors: D
authors: Tsakpinis
authors: Mayssa B
authors: MB
authors: Nasr
authors: Paris
authors: P
authors: Tranos
authors: Nikos
authors: N
authors: Krassas
authors: Theodoros
authors: T
authors: Giannopoulos
authors: Chrysanthos
authors: C
authors: Symeonidis
authors: Stavros A
authors: SA
authors: Dimitrakos
authors: Anastasios Gp
authors: AG
authors: Konstas