title: Lethal hemorrhagic alveolitis after adenovirus pneumonia in a lung transplant recipient.
abstract: Viral infections are frequent and severe in lung transplant recipients. They frequently occur during the first year after transplantation. We report on a rare case of bilateral adenovirus necrotizing pneumonia with a diffuse alveolar hemorrhage, 4 years after bilateral lung transplantation. The medical evolution was lethal in 72 hours because of respiratory, renal, and cardiac failure. Considering this case and the growing evidence on the severity of adenoviral infections, we call for controlled studies and therapeutic recommendations.
authors: Département d'Anesthésie Réanimation, Université Paul Sabatier Toulouse III, Hôpital Purpan, Toulouse, France. nicolas.mayeur@inserm.fr
authors: Nicolas
authors: N
authors: Mayeur
authors: Mohamed
authors: M
authors: Srairi
authors: Laurent
authors: L
authors: Tetu
authors: Céline
authors: C
authors: Guilbeau Frugier
authors: Olivier
authors: O
authors: Fourcade
authors: Marcel
authors: M
authors: Dahan
mesh_terms: D000258:Adenovirus Infections, Human / Q000150:complications*; D003550:Cystic Fibrosis / Q000601:surgery; D017809:Fatal Outcome; D006470:Hemorrhage / Q000150:complications*; D006801:Humans; D017563:Lung Diseases, Interstitial / Q000209:etiology*; D016040:Lung Transplantation; D008297:Male; D009336:Necrosis; D011024:Pneumonia, Viral / Q000150:complications* / Q000473:pathology; D011183:Postoperative Complications; D011650:Pulmonary Alveoli; D055815:Young Adult