title: Lymphadenectomy in urologic oncology: pathologic considerations.
abstract: Lymphadenectomy (LAD) is an important staging and treatment modality of oncologic surgery. LAD in genitourinary malignancies presents inherent difficulties to the urologist and pathologist because of the differences in anatomic sites and primary histologic type. This review focuses on pathologic evaluation and how communication between urologist and pathologist is necessary to provide optimal care. Recommendations covering general specimen submission and processing are discussed, as well as more specific recommendations concerning the kidney, upper urinary tract, urinary bladder, prostate, testes, and penis. Emerging areas of prognostic significance and the impact that improved molecular techniques are contributing to diagnostic interpretation are highlighted.
authors: Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Room 4010, 350 West 11th Street, Indianapolis, IN 46202, USA.
authors: Riley E
authors: RE
authors: Alexander
authors: Ming-Tse
authors: MT
authors: Sung
authors: Liang
authors: L
authors: Cheng
mesh_terms: D001707:Biopsy, Needle; D002295:Carcinoma, Transitional Cell / Q000401:mortality / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007150:Immunohistochemistry; D008197:Lymph Node Excision / Q000379:methods*; D008198:Lymph Nodes / Q000473:pathology*; D008297:Male; D009361:Neoplasm Invasiveness / Q000473:pathology; D009367:Neoplasm Staging; D011379:Prognosis; D018570:Risk Assessment; D021701:Sentinel Lymph Node Biopsy; D016019:Survival Analysis; D016896:Treatment Outcome; D014565:Urogenital Neoplasms / Q000401:mortality / Q000473:pathology* / Q000601:surgery