title: Graft-versus-host disease after kidney transplantation.
abstract: Graft-versus-host disease (GVHD) is a rare complication after kidney transplantation. We describe a 62-year-old female with end-stage renal disease due to hypertension. She received a kidney with 4 mismatched human leukocyte antigen (HLA) out of 6 HLA - A, B, DR from a deceased donor. After the procedure, the patient showed watery diarrhea on postoperative day (POD) 45. An endoscopic biopsy of the colon revealed some apoptotic cells consistent with GVHD. Thrombocytopenia was gradually developed on POD 54. She received steroid pulse therapy, and thrombocytopenia did not progress. However, pneumonia, renal failure, and cardiac failure occurred. She died due to multiple organ failure. We must consider GVHD in renal transplant recipients without homozygous or identical HLA, who had only watery diarrhea without other typical GVHD symptoms such as skin rash and fever, although GVHD is rare in renal transplant recipients.
authors: Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
authors: Jong Man
authors: JM
authors: Kim
authors: Sung Joo
authors: SJ
authors: Kim
authors: Jae-Won
authors: JW
authors: Joh
authors: Choon Hyuck David
authors: CH
authors: Kwon
authors: Kee-Taek
authors: KT
authors: Jang
authors: Jungsuk
authors: J
authors: An
authors: Chang-Seok
authors: CS
authors: Ki
authors: Eun-Suk
authors: ES
authors: Kang
authors: Milljae
authors: M
authors: Shin
authors: Bok Nyeo
authors: BN
authors: Kim
authors: Suk-Koo
authors: SK
authors: Lee