title: Plant TOR signaling components.
abstract: Cell growth is a process that needs to be tightly regulated. Cells must be able to sense environmental factors like nutrient abundance, the energy level or stress signals and coordinate growth accordingly. The Target Of Rapamycin (TOR) pathway is a major controller of growth-related processes in all eukaryotes. If environmental conditions are favorable, the TOR pathway promotes cell and organ growth and restrains catabolic processes like autophagy. Rapamycin is a specific inhibitor of the TOR kinase and acts as a potent inhibitor of TOR signaling. As a consequence, interfering with TOR signaling has a strong impact on plant development. This review summarizes the progress in the understanding of the biological significance and the functional analysis of the TOR pathway in plants.
authors: Institute of Plant Biology, University of Zürich, Zürich, Switzerland.
authors: Florian
authors: F
authors: John
authors: Stefan
authors: S
authors: Roffler
authors: Thomas
authors: T
authors: Wicker
authors: Christoph
authors: C
authors: Ringli
mesh_terms: D002473:Cell Wall / Q000378:metabolism; D059828:Plant Cells; D010940:Plant Proteins / Q000378:metabolism*; D010944:Plants / Q000201:enzymology*; D015398:Signal Transduction / Q000187:drug effects; D020123:Sirolimus / Q000494:pharmacology; D058570:TOR Serine-Threonine Kinases / Q000037:antagonists & inhibitors / Q000378:metabolism*
chemical_list: D010940:Plant Proteins; D058570:TOR Serine-Threonine Kinases; D020123:Sirolimus