title: Role of tracheal resection in thyroid cancer.
abstract: OBJECTIVE
  To provide a critical review of recent literature on the role of tracheal resection in thyroid cancer.
  
  
  RESULTS
  The current body of literature is centered on the controversy regarding how radical the extent of tracheal resection needs to be to achieve long-term control of thyroid carcinoma with tracheal invasion. Proponents of shave excision are guided by the reported survival outcomes comparable to segmental resections in a selected group of patients. Others believe that all patients should have a segmental sleeve resection to ensure clearance of transmural disease. Recent advances in microsurgical reconstruction may allow selected patients to undergo tracheal resection when a large tracheal defect is anticipated.
  
  
  CONCLUSIONS
  Tracheal invasion by well differentiated carcinoma is a marker of a more aggressive tumor behavior, defining a subpopulation of patients at a greater risk of recurrence and death. The goal of surgical intervention in this scenario is complete resection with no gross residual disease. A well designed prospective multi-institutional trial, taking into account depth of invasion, risk group stratification, histology, presence of distant metastasis, radioactive iodine trapping ability, adjuvant treatment, and long-term survival data, is needed to compare the outcomes following more conservative shave excision and segmental tracheal resection.
authors: Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
authors: Natalya
authors: N
authors: Chernichenko
authors: Ashok R
authors: AR
authors: Shaha
mesh_terms: D006801:Humans; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D013964:Thyroid Neoplasms / Q000473:pathology / Q000601:surgery*; D014140:Tracheotomy / Q000379:methods*