title: AIDS-associated paracoccidioidomycosis in a patient with a CD4+ T-cell count of 4 cells/mm³.
abstract: We describe a case of a patient presenting with HIV and paracoccidioidomycosis co-infection. At the time of diagnosis total CD4+ T-cell count was 4 cells/mm3. Histopathology revealed tuberculoid granulomas, scarce CD4+ T cells, a moderate number of CD8+ cells and the absence of Foxp3+ cells. Most of the cutaneous lesions healed after two weeks of treatment with amphotericin B. After 14 months the patient is still under antiretroviral therapy and no clinical evidence of recurrence of the mycosis has been observed.
authors: Tropical Medicine Foundation of Amazonas, Manaus, Amazonas, Brazil.
authors: Lisiane Machado Contente
authors: LM
authors: Nogueira
authors: Mônica
authors: M
authors: Santos
authors: Luiz Carlos de Lima
authors: LC
authors: Ferreira
authors: Carolina
authors: C
authors: Talhari
authors: Rodrigo Ribeiro
authors: RR
authors: Rodrigues
authors: Sinésio
authors: S
authors: Talhari
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000276:immunology* / Q000473:pathology; D000328:Adult; D018791:CD4 Lymphocyte Count; D015496:CD4-Positive T-Lymphocytes / Q000276:immunology*; D005260:Female; D006801:Humans; D010229:Paracoccidioidomycosis / Q000276:immunology* / Q000473:pathology