title: Nodal/Activin signaling: a novel target for pancreatic cancer stem cell therapy.
abstract: Targeting of cancer stem cells (CSCs) has the potential to address the recalcitrance of pancreatic cancer to chemotherapy. In this issue of Cell Stem Cell, Lonardo et al. (2011) demonstrate that Nodal/Activin signaling is crucial for the maintenance and tumor-initiating capacity of pancreatic CSCs.
authors: Departments of Surgery and Molecular and Medical Pharmacology, David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, CA 90095, USA.
authors: Timothy R
authors: TR
authors: Donahue
authors: David W
authors: DW
authors: Dawson