title: Effects of a dietary supplement on chronic pelvic pain syndrome (Category IIIA), leucocytospermia and semen parameters.
abstract: Chronic prostatitis (CP) is one of the most common male urogenital diseases and a significant public health problem in industrialised countries. It is associated with a low quality of life and significant expense. Given the poor results achieved with antibiotics, scientific interest has turned to the use of natural substances with a known activity on prostate function. The aim of our study was to evaluate the effect of a new dietary supplement containing lycopene, epigallocatechin gallate, ellagic acid, selenium and zinc on semen parameters and on leucocyte concentration in seminal fluid and expressed prostate secretion (EPS) in patients with CP without infection [National Institute of Health (NIH) Category IIIA], in comparison with a control group with the same condition who did not undergo any treatment during the study period. Our data showed a statistically significant reduction in inflammatory parameters (leucocytes in seminal fluid and EPS) and a statistically significant improvement in progressive sperm motility and sperm morphology in patients treated with the supplement in comparison with the untreated group. Improvements were also seen in the pain score of the NIH-Chronic Prostatitis Symptom Index (CPSI), confirming that the reduced inflammation also resulted in a reduction in pain.
authors: Department of Experimental Medicine, Policlinico Umberto I, University of Rome La Sapienza, Rome, Italy. francesco.lombardo@uniroma1.it
authors: F
authors: F
authors: Lombardo
authors: M
authors: M
authors: Fiducia
authors: R
authors: R
authors: Lunghi
authors: L
authors: L
authors: Marchetti
authors: A
authors: A
authors: Palumbo
authors: F
authors: F
authors: Rizzo
authors: A
authors: A
authors: Koverech
authors: A
authors: A
authors: Lenzi
authors: L
authors: L
authors: Gandini
mesh_terms: D000328:Adult; D002908:Chronic Disease; D019587:Dietary Supplements; D006801:Humans; D008297:Male; D017699:Pelvic Pain / Q000628:therapy*; D012661:Semen