title: Natural plant genetic engineer Agrobacterium rhizogenes: role of T-DNA in plant secondary metabolism.
abstract: Agrobacterium                         rhizogenes is a natural plant genetic engineer. It is a gram-negative soil bacterium that induces hairy root formation. Success has been obtained in exploring the molecular mechanisms of transferred DNA (T-DNA) transfer, interaction with host plant proteins, plant defense signaling and integration to plant genome for successful plant genetic transformation. T-DNA and corresponding expression of rol genes alter morphology and plant host secondary metabolism. During transformation, there is a differential loss of a few T-DNA genes. Loss of a few ORFs drastically affect the growth and morphological patterns of hairy roots, expression pattern of biosynthetic pathway genes and accumulation of specific secondary metabolites.
authors: Birla Institute of Technology, Mesra, Ranchi, Jharkhand 835215, India. schandra@bitmesra.ac.in
authors: Sheela
authors: S
authors: Chandra
mesh_terms: D060054:Agrobacterium / Q000235:genetics*; D004269:DNA, Bacterial; D005798:Genes, Bacterial; D060847:Metabolic Engineering; D010944:Plants / Q000378:metabolism* / Q000382:microbiology*; D030821:Plants, Genetically Modified; D014170:Transformation, Genetic
chemical_list: D004269:DNA, Bacterial; C036483:T-DNA