title: [Quality of fat intake, atherosclerosis and coronary disease: effects of saturated and trans fatty acids].
abstract: Epidemiological, clinical and metabolic research has shown a strong association between dietary fatty acids intake and cardiovascular disease (CVD) risk factors and clinical events. Saturated fatty acids (SFA) and trans fatty acids (TFA) derived from industrial hydrogenation of oils have been associated with an increased prevalence of CVD. However experimental results on the relationship between physiological pathologic effects and specific functions of individual SFA are often contradictory. Therefore a more detailed exploration of the potential benefit and risks of specific saturated and trans fatty acids is needed in order to update dietary recommendations. In the case of TFAs, the deleterious effect on CVD has been well demonstrated and a maximum accepted level of 1 % of total energy has been agreed internationally. What is currently under discussion is what would be the best alternative to replace them in the diet.
authors: Departamento de Pediatría, Universidad de Chile, Campus Norte, Hospital Roberto del Río, Santiago, Chile. torrejon_clau@yahoo.com
authors: Claudia
authors: C
authors: Torrejón
authors: Ricardo
authors: R
authors: Uauy
mesh_terms: D000818:Animals; D050197:Atherosclerosis / Q000209:etiology*; D003327:Coronary Disease / Q000209:etiology*; D004041:Dietary Fats / Q000008:administration & dosage / Q000009:adverse effects*; D002149:Energy Intake; D005227:Fatty Acids / Q000008:administration & dosage / Q000009:adverse effects; D006801:Humans; D012307:Risk Factors; D044242:Trans Fatty Acids / Q000008:administration & dosage / Q000009:adverse effects*
chemical_list: D004041:Dietary Fats; D005227:Fatty Acids; D044242:Trans Fatty Acids