title: [A case-control study of the transmission of pandemic influenza A (H1N1) virus in families].
abstract: OBJECTIVE
  To explore the characteristics of transmission of pandemic influenza A/H1N1, and to analyze the possible factors of influencing transmission in families and to provide scientific evidence for formulating strategies of H1N1 prevention and control.
  
  
  METHODS
  A 1:2 matched case-control study was conducted. The case was defined as a household with 2 or more cases and the control was defined as that with 1 case. Face-to-face interview with questionnaire was used to collect information of work and family life of the study participants. Conditional logistic regression was used to analyze the data.
  
  
  RESULTS
  Univariate analysis showed that factors such as education level of the secondary case, the number of family members, per capita living space, flu-like symptom, insulation of case, ventilation, hand-washing, and influenza A/H1N1 vaccine immunization were all associated with infection of influenza A/H1N1. Results of multivariate logistic regression analysis showed that variables such as education level of secondary case (OR = 0.42), insulation of case (OR = 3.29), ventilation, (OR = 0.28), hand-washing (OR = 0.71), influenza A/H1N1 vaccine immunization (OR = 0.05) were all correlated to infection of influenza A/H1N1.
  
  
  CONCLUSIONS
  Factors such as vaccine, insulation, ventilation, and hand-washing can help persons in protection from infection of influenza A/H1N1, suggesting the importance of good hygienic habit and immunization with influenza A/H1N1 vaccine.
authors: Beijing Center for Disease Prevention and Control, Beijing 100013, China.
authors: Wen-ting
authors: WT
authors: Liu
authors: Xing-huo
authors: XH
authors: Pang
authors: Ying
authors: Y
authors: Deng
authors: Peng
authors: P
authors: Yang
authors: Xin-yu
authors: XY
authors: Li
authors: Yi
authors: Y
authors: Zhang
authors: Wei
authors: W
authors: Duan
authors: Xiao-li
authors: XL
authors: Wang
authors: Quan-yi
authors: QY
authors: Wang
mesh_terms: D000293:Adolescent; D000328:Adult; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D004196:Disease Outbreaks / Q000517:prevention & control*; D005191:Family Characteristics; D005260:Female; D006801:Humans; D007223:Infant; D053118:Influenza A Virus, H1N1 Subtype; D007251:Influenza, Human / Q000517:prevention & control / Q000635:transmission* / Q000821:virology; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D011795:Surveys and Questionnaires; D055815:Young Adult