title: Refractory endemic pemphigus foliaceous in adolescence successfully treated with intravenous immunoglobulin.
abstract: Endemic Pemphigus Foliaceous is a chronic autoimmune bullous skin disease. Treatment with prednisone often produces excellent results, but resistant forms exist, requiring alternative therapy. Alternative treatments have been used in cases of corticosteroid-refractory pemphigus, showing favorable results. This case study focuses on an adolescent male with a clinical-pathological diagnosis of pemphigus foliaceous with a severe clinical form of erythrodermis, unresponsive to multiple therapies, but which showed a satisfactory outcome with intravenous immunoglobulin. In this case we highlight the fact that the patient was a teenager who showed substantial clinical improvement as the result of using intravenous immunoglobulin, followed by complete remission after the fourth cycle of medication, allowing reduced doses of steroids and a consequent reduction of side effects.
authors: Serviço de Dermatologia, Hospital das Clínicas, Universidade Federal de Goiás, Goiânia, Brasil. talitateixeira@hotmail.com
authors: Talita Alves
authors: TA
authors: Teixeira
authors: Fernanda Coelho Barbosa da Cruz
authors: FC
authors: Fiori
authors: Marilene Chaves
authors: MC
authors: Silvestre
authors: Camilla de Barros
authors: Cde B
authors: Borges
authors: Vanessa Gomes
authors: VG
authors: Maciel
authors: Mauricio Barcelos
authors: MB
authors: Costa
mesh_terms: D000293:Adolescent; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use*; D007155:Immunologic Factors / Q000627:therapeutic use*; D008297:Male; D010392:Pemphigus / Q000188:drug therapy* / Q000473:pathology; D016896:Treatment Outcome
chemical_list: D016756:Immunoglobulins, Intravenous; D007155:Immunologic Factors