title: Helicobacter pylori infection and acute myocardial infarction.
abstract: The aim of this investigation was to determine whether H. pylori infection is an independent risk factor for acute myocardial infarction (AMI), determine is there a link between H. pylori infection and severity of disease. In this prospective, single centre study, were enrolled 100 patients with AMI and control group was consisted 93 healthy individuals. The results of this study showed no difference between H. pylori seropositivity distribution in the investigate and control group (29 vs. 26 %) and there was no significant difference on the severity of the disease. There was significant association in the patients with three and more risk factors, where the patients with lower blood pressure (124.4/77.4 vs. 145.9/87.7 mmHg) and better controlled diabetes (HbA1c 6.1% vs. 6.9%) had greater risk for AMI if they are H. pylori seropositive. The large multicentric trials would be needed to define a precise role of H. pylori infection on the developement of AMI.
authors: General Hospital Zadar, Department of Internal Medicine, Zadar, Croatia. dario.nakic@zd.t-com.hr
authors: Dario
authors: D
authors: Nakić
authors: Aleksandar
authors: A
authors: Vcev
authors: Albino
authors: A
authors: Jović
authors: Jogen
authors: J
authors: Patrk
authors: Drazen
authors: D
authors: Zekanović
authors: Ivo
authors: I
authors: Klarin
authors: Kresimir
authors: K
authors: Ivanac
authors: Anamarija
authors: A
authors: Mrden
authors: Sanja
authors: S
authors: Balen
mesh_terms: D000368:Aged; D005260:Female; D016481:Helicobacter Infections / Q000150:complications*; D016480:Helicobacter pylori; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000209:etiology*; D011446:Prospective Studies; D012307:Risk Factors