title: A rare ovarian Leydig cell tumor (hilar type) causing virilization in a postmenopausal woman.
abstract: All patients with virilization signs, increased levels of androgen hormones and rapidly progressive hirsutism should be evaluated for an androgen-producing tumor. The ovarian origin of virilization can be suspected by the presence of elevated levels of circulating androgens, with normal levels of cortisol metabolites and a negative dexamethasone suppression test. A case report of a 50-year-old postmenopausal patient with rapidly progressive hirsutism is presented. After an extensive preoperative investigation a right oophorectomy was performed and a Leydig-hilus cell tumor was diagnosed.
authors: Pathology Department, Aretaieion University Hospital, University of Athens, Greece.
authors: E
authors: E
authors: Vouza
authors: E
authors: E
authors: Kairi-Vassilatou
authors: C K
authors: CK
authors: Kleanthis
authors: N
authors: N
authors: Hasiakos
authors: N
authors: N
authors: Salakos
authors: A
authors: A
authors: Kondi-Pafiti
mesh_terms: D005260:Female; D006628:Hirsutism / Q000209:etiology; D006801:Humans; D007984:Leydig Cell Tumor / Q000150:complications* / Q000473:pathology / Q000601:surgery; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000150:complications* / Q000473:pathology / Q000601:surgery; D010052:Ovariectomy; D017698:Postmenopause; D014770:Virilism / Q000209:etiology*