title: Hyperkeratosis lenticularis perstans.
abstract: Flegel's disease, also known as hyperkeratosis lenticularis perstans, is a rare skin disease characterized by small reddish-brown asymptomatic hyperkeratotic papules usually located on the lower extremities. The histopathological features are hyperorthokeratosis, epidermal atrophy and band-like inflammatory infiltrate in the superficial dermis. Treatment is generally ineffective. We report a case of hyperkeratosis lenticularis perstans that improved following excisional biopsy of the lesions.
authors: UNOESC, University of Western Santa Catarina, Joacaba, SC, Brazil. robertodermatologista@yahoo.com.br
authors: Roberto Rheingantz da
authors: RR
authors: Cunha Filho
authors: Hiram Larangeira de
authors: HL
authors: Almeida
mesh_terms: D000328:Adult; D001706:Biopsy; D005533:Foot Dermatoses / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007642:Keratosis / Q000473:pathology* / Q000601:surgery; D008297:Male