title: Effects of the polysaccharide from Pholiota nameko on human cytokine network in serum.
abstract: Some physico-chemical characterizations of Pholiota nameko polysaccharides (PNPS-1) were studied, including sulfate content, UV/visible and infrared spectra, also the variation of cytokine communication network in serum to clarify the pharmacological effects of PNPS-1 by determination of 39 cytokines in serum of healthy volunteers. The result proved that PNPS-1 possessed significant anti-inflammatory activity. Further, we use Microsoft Visio 2007 software to map out the cell-cell communication network diagram. The analysis to the diagram suggested that PNPS-1 could take effect on the innate and adaptive immunity and hematopoiesis of volunteers.
authors: Tianjin Key Laboratory of Food Biotechnology, Faculty of Biotechnology and Food Science, Tianjin University of Commerce, Tianjin, PR China. hhppli@163.com
authors: Haiping
authors: H
authors: Li
authors: Xiaojuan
authors: X
authors: Liu
authors: Yang
authors: Y
authors: Li
authors: Yanjun
authors: Y
authors: Hua
authors: Dexian
authors: D
authors: Zhi
authors: Guangchang
authors: G
authors: Pang
mesh_terms: D000328:Adult; D002450:Cell Communication; D002627:Chemistry, Physical / Q000379:methods; D016207:Cytokines / Q000096:biosynthesis* / Q000378:metabolism; D005260:Female; D006801:Humans; D007249:Inflammation; D008297:Male; D015233:Models, Statistical; D055368:Pholiota / Q000378:metabolism*; D011134:Polysaccharides / Q000737:chemistry*; D011485:Protein Binding; D012984:Software; D013056:Spectrophotometry, Ultraviolet / Q000379:methods; D017550:Spectroscopy, Fourier Transform Infrared / Q000379:methods; D013997:Time Factors
chemical_list: D016207:Cytokines; D011134:Polysaccharides