title: [Clinical courses and pregnancy outcomes in Japanese women with inflammatory bowel disease].
abstract: In this study, we analyzed the clinical courses and the pregnancy outcomes in Japanese women with inflammatory bowel disease (IBD) in our hospital in the recent 10 years. We analyzed 49 pregnancies in 38 patients with ulcerative colitis (UC) and 24 pregnancies in 16 patients with Crohn's disease (CD) retrospectively. The results indicated that pregnancy has less influence on the clinical courses of IBD and that IBD also has less influence on the pregnancy outcomes. However, we should pay attention to the results that the patients with CD tend to deteriorate if conception occurs when CD is active and that patients with active UC tend to have more adverse pregnancy outcomes than patients in remission. In conclusion, patients with IBD are recommended to become pregnant when the diseases are in remission and treatment using selected safe medications should be continued during the pregnancy.
authors: Division of Gastroenterology, Tohoku University Hospital.
authors: Katsuya
authors: K
authors: Endo
authors: Seiichi
authors: S
authors: Takahashi
authors: Yosuke
authors: Y
authors: Shimodaira
authors: Hitoshi
authors: H
authors: Nagasawa
authors: Rintaro
authors: R
authors: Moroi
authors: Masatake
authors: M
authors: Kuroha
authors: Takashi
authors: T
authors: Arai
authors: Yoshitake
authors: Y
authors: Kanazawa
authors: Hisashi
authors: H
authors: Shiga
authors: Yoichi
authors: Y
authors: Kakuta
authors: Yoshitaka
authors: Y
authors: Kinouchi
authors: Tooru
authors: T
authors: Shimosegawa
mesh_terms: D000328:Adult; D003093:Colitis, Ulcerative / Q000503:physiopathology; D003424:Crohn Disease / Q000503:physiopathology; D005260:Female; D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000503:physiopathology*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000503:physiopathology*; D011256:Pregnancy Outcome