title: Composition and antibacterial activity of essential oil from Scutellaria grossa Wall ex Benth.
abstract: The chemical composition of the steam volatile oil of the whole aerial part of Scutellaria grossa Wall ex Benth. (Lamiaceae), obtained by steam distillation, has been analysed by capillary GC and GC-MS. The oil was found to be rich in oxygenated monoterpenes (88.6%). A total of 50 constituents were identified, representing 94.4% of the total oil composition. Linalool (37.0%) and 1-octen-3-ol (32.0%) were found to be the principal constituents. The antibacterial activity of the oil was determined against 10 bacterial strains by measuring the growth inhibitory zones. The oil showed significant antibacterial activity against Gram-positive bacteria, Bacillus subtilis and Enterococcus faecalis, and the Gram-negative, Klebsiella pneumoniae and Salmonella enterica enterica. A minimum inhibitory concentration of 31.25 µL mL(-1) was observed against E. faecalis.
authors: Department of Chemistry, Kumaun University, Nainital 263002, Uttarakhand, India.
authors: Charu C
authors: CC
authors: Pant
authors: Anand B
authors: AB
authors: Melkani
authors: Lalit
authors: L
authors: Mohan
authors: Vasu
authors: V
authors: Dev
mesh_terms: D000080462:Acyclic Monoterpenes; D000900:Anti-Bacterial Agents / Q000032:analysis* / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects*; D002849:Chromatography, Gas; D008401:Gas Chromatography-Mass Spectrometry; D008826:Microbial Sensitivity Tests; D039821:Monoterpenes / Q000032:analysis*; D000442:Octanols / Q000032:analysis; D009822:Oils, Volatile / Q000737:chemistry* / Q000494:pharmacology; D035261:Plant Components, Aerial / Q000737:chemistry*; D031363:Scutellaria / Q000737:chemistry*; D013045:Species Specificity; D013227:Steam
chemical_list: D000080462:Acyclic Monoterpenes; D000900:Anti-Bacterial Agents; D039821:Monoterpenes; D000442:Octanols; D009822:Oils, Volatile; D013227:Steam; C018584:linalool; C038844:1-octen-3-ol