title: Phylogenetic study of the species within the family Streptomycetaceae.
abstract: Species of the genus Streptomyces, which constitute the vast majority of taxa within the family Streptomycetaceae, are a predominant component of the microbial population in soils throughout the world and have been the subject of extensive isolation and screening efforts over the years because they are a major source of commercially and medically important secondary metabolites. Taxonomic characterization of Streptomyces strains has been a challenge due to the large number of described species, greater than any other microbial genus, resulting from academic and industrial activities. The methods used for characterization have evolved through several phases over the years from those based largely on morphological observations, to subsequent classifications based on numerical taxonomic analyses of standardized sets of phenotypic characters and, most recently, to the use of molecular phylogenetic analyses of gene sequences. The present phylogenetic study examines almost all described species (615 taxa) within the family Streptomycetaceae based on 16S rRNA gene sequences and illustrates the species diversity within this family, which is observed to contain 130 statistically supported clades, as well as many unsupported and single member clusters. Many of the observed clades are consistent with earlier morphological and numerical taxonomic studies, but it is apparent that insufficient variation is present in the 16S rRNA gene sequence within the species of this family to permit bootstrap-supported resolution of relationships between many of the individual clusters.
authors: National Center for Agricultural Utilization Research, U.S. Department of Agriculture-Agricultural Research Service, 1815 North University Street, Peoria, IL 61604, USA. David.Labeda@ars.usda.gov
authors: D P
authors: DP
authors: Labeda
authors: M
authors: M
authors: Goodfellow
authors: R
authors: R
authors: Brown
authors: A C
authors: AC
authors: Ward
authors: B
authors: B
authors: Lanoot
authors: M
authors: M
authors: Vanncanneyt
authors: J
authors: J
authors: Swings
authors: S-B
authors: SB
authors: Kim
authors: Z
authors: Z
authors: Liu
authors: J
authors: J
authors: Chun
authors: T
authors: T
authors: Tamura
authors: A
authors: A
authors: Oguchi
authors: T
authors: T
authors: Kikuchi
authors: H
authors: H
authors: Kikuchi
authors: T
authors: T
authors: Nishii
authors: K
authors: K
authors: Tsuji
authors: Y
authors: Y
authors: Yamaguchi
authors: A
authors: A
authors: Tase
authors: M
authors: M
authors: Takahashi
authors: T
authors: T
authors: Sakane
authors: K I
authors: KI
authors: Suzuki
authors: K
authors: K
authors: Hatano
mesh_terms: D016000:Cluster Analysis; D004269:DNA, Bacterial / Q000737:chemistry / Q000235:genetics; D004275:DNA, Ribosomal / Q000737:chemistry / Q000235:genetics; D010802:Phylogeny; D012336:RNA, Ribosomal, 16S / Q000235:genetics; D017422:Sequence Analysis, DNA; D012988:Soil Microbiology; D013306:Streptomycetaceae / Q000145:classification* / Q000235:genetics* / Q000302:isolation & purification
chemical_list: D004269:DNA, Bacterial; D004275:DNA, Ribosomal; D012336:RNA, Ribosomal, 16S