title: A new method for fabricating a CuO/TiO2 nanotube arrays electrode and its application as a sensitive nonenzymatic glucose sensor.
abstract: In this report, we presented a new method to fabricate TiO(2) nanotube (TiO(2) NT) arrays modified with cupric oxide (CuO) nanofibers, getting a novel TiO(2) NT arrays composition electrode for sensitive nonenzymatic glucose detection. For the preparation of CuO nanofibers, Cu nanoparticles were firstly electrodeposited onto the TiO(2) NT arrays, and then oxidized to CuO nanofibers followed by annealing in air. The CuO nanofibers modified TiO(2) NT (CuO/TiO(2) NT) arrays electrode for electrocatalytic detection of glucose was investigated by cyclic voltammetry and chronoamperometry in 0.10 M NaOH solution. The linear range of detection of glucose extended up to 2.0mM (R=0.997, n=10) at a potential of 0.50 V (vs. SCE). The sensitivity was 79.79 μA cm(-2)mM(-1), and the detection limit was 1 μM (S/N=3). Significantly, the poisoning by chloride ion and the interferences from ascorbic acid, uric acid, lactose, sucrose, fructose and dopamine were negligible. Particularly, the CuO/TiO(2) NT arrays electrode showed excellent stability and repeatability over 1 month. The sensor was also investigated detecting glucose in human blood serum samples.
authors: State Key Laboratory of Chemo/Biosensing and Chemometrics, Hunan University, Changsha 410082, PR China. sllou@hnu.cn
authors: Shenglian
authors: S
authors: Luo
authors: Fang
authors: F
authors: Su
authors: Chengbin
authors: C
authors: Liu
authors: Juanxiu
authors: J
authors: Li
authors: Ronghua
authors: R
authors: Liu
authors: Yan
authors: Y
authors: Xiao
authors: Yue
authors: Y
authors: Li
authors: Xuanneng
authors: X
authors: Liu
authors: Qingyun
authors: Q
authors: Cai
mesh_terms: D015374:Biosensing Techniques / Q000295:instrumentation / Q000379:methods*; D001786:Blood Glucose; D003300:Copper / Q000737:chemistry*; D003461:Crystallography / Q000295:instrumentation / Q000379:methods; D004566:Electrodes; D005947:Glucose / Q000032:analysis*; D006801:Humans; D043942:Nanotubes / Q000737:chemistry*; D014025:Titanium / Q000737:chemistry*
chemical_list: D001786:Blood Glucose; C009495:titanium dioxide; D003300:Copper; D014025:Titanium; D005947:Glucose; C030973:cupric oxide