title: A PGC-1 tale: healthier intestinal stem cells, longer life.
abstract: PGC-1 regulates energy homeostasis and mitochondrial activity. In this issue, Rera et al. (2011) show that dPGC-1 overexpression in Drosophila intestinal stem cells and their immediate progeny extends organismal life span and protects against age-related loss of intestinal homeostasis and integrity, thereby establishing a link between mitochondria, tissue stem cells, and aging.
authors: Stowers Institute for Medical Research, 1000 East 50th Street, Kansas City, MO 64110, USA.
authors: Yi
authors: Y
authors: Zhou
authors: Tinglin
authors: T
authors: Lu
authors: Ting
authors: T
authors: Xie