title: Dementia in Parkinson's disease: a Brazilian sample.
abstract: To determine the prevalence of dementia associated with Parkinson's disease (PD-D) in a Brazilian sample adopting clinical and diagnostic procedures recommended by the Movement Disorders Society (MDS). Sixty-seven patients were consecutively submitted to neurological, neuropsychological and functional examinations. PD-D was established according to MDS clinical criteria (Level II) and clinical procedures for PD-D (Level I) and prevalence rate was compared between the levels adopted. Ten patients (14.9%) were diagnosed as demented by Level I criteria whereas sixteen (23.8%) were diagnosed based on Level II criteria. Level I criteria had low sensitivity in detecting PD-D (31.25%), but greater specificity (90.19). The PD-D group had significantly worse performance on all neuropsychological tests, were older (p<0.001), had an older age of onset of disease (p<0.01), had lower educational level (p<0.02) and had higher scores on functional scales. Current age (p=0.046) and Hoehn & Yahr score (p=0.048) were predictors for developing PD-D.
authors: Service of Neurology, Santa Marcelina Hospital, São Paulo SP, Brazil. bbaldivia@gmail.com
authors: Beatriz
authors: B
authors: Baldivia
authors: Sonia Maria Dozzi
authors: SM
authors: Brucki
authors: Silmara
authors: S
authors: Batistela
authors: Juliana Carvalho
authors: JC
authors: Esper
authors: Cristiano Duarte
authors: CD
authors: Augusto
authors: Maria Sheila Guimarães
authors: MS
authors: Rocha
mesh_terms: D000368:Aged; D001938:Brazil / Q000453:epidemiology; D003704:Dementia / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D010300:Parkinson Disease / Q000150:complications*; D011237:Predictive Value of Tests; D015995:Prevalence; D011569:Psychiatric Status Rating Scales; D012680:Sensitivity and Specificity