title: Metabolic syndrome, lifestyle risk factors, and distal colon adenoma: a retrospective cohort study.
abstract: OBJECTIVE
  To investigate relationships between colorectal adenoma incidence, metabolic syndrome (MS) components and lifestyle factors.
  
  
  METHODS
  We conducted a retrospective cohort study using data from individuals who had multiple sigmoidoscopies for colon cancer at the Health Promotion Center of Ulsan University Hospital in Korea from 1998 to 2007.
  
  
  RESULTS
  By multivariate analysis, the incidence of distal colon adenoma was increased by more than 1.76 times in individuals with at least one component of MS compared to those without a component of MS. After adjustment for age, gender, smoking, drinking, and physical exercise, only high body mass index (BMI) was significantly associated with the incidence of distal colon adenoma (Hazard ratio 1.66, 95% confidence interval 1.05-2.62).
  
  
  CONCLUSIONS
  Our results suggest that high BMI may increase the risk of colorectal adenoma in Korean adults.
authors: Department of Family Medicine, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan 682-714, South Korea.
authors: Moon-Chan
authors: MC
authors: Kim
authors: Chang-Sup
authors: CS
authors: Kim
authors: Tae-Heum
authors: TH
authors: Chung
authors: Hyoung-Ouk
authors: HO
authors: Park
authors: Cheol-In
authors: CI
authors: Yoo
mesh_terms: D000236:Adenoma / Q000453:epidemiology / Q000209:etiology* / Q000473:pathology; D000328:Adult; D015992:Body Mass Index; D015331:Cohort Studies; D015179:Colorectal Neoplasms / Q000453:epidemiology / Q000209:etiology* / Q000473:pathology; D005260:Female; D006801:Humans; D008019:Life Style; D008297:Male; D024821:Metabolic Syndrome / Q000150:complications* / Q000209:etiology*; D008875:Middle Aged; D009765:Obesity / Q000150:complications*; D056910:Republic of Korea / Q000453:epidemiology; D012189:Retrospective Studies; D012307:Risk Factors; D011795:Surveys and Questionnaires; D055815:Young Adult