title: Comparative study of surgical margins and cosmetic outcome in lumpectomy versus segmental resection in breast cancer.
abstract: OBJECTIVE
  The aim of the present retrospective study was to compare two breast-conserving techniques, segmental resection and standard lumpectomy, for the treatment of breast cancer regarding their oncological safety. Quality of life aspects were evaluated by assessing the respective postsurgical cosmetic results.
  
  
  METHODS
  190 women with breast cancer located in the superior and lateral quadrant were included in the study. Sixty patients were treated with segmental resection (group 1), whereas 130 underwent standard lumpectomy (group 2). Tumor sizes were determined and excised tissue specimens were analyzed for positive or negative resection margins. Patients were given a 16-item questionnaire for the postsurgical self-assessment of the cosmetic outcome.
  
  
  RESULTS
  No statistically significant difference was found concerning the number of positive resection margins between the groups (25 vs. 30%, p = 0.46). Exceptions were ventral margins, which predominated in group 2 (p = 0.016). Group 1 revealed a significantly larger maximum tumor size with negative margins as compared to group 2 (26.6 vs. 17.0 mm). General satisfaction with the cosmetic results was comparable between groups.
  
  
  CONCLUSIONS
  Segmental resection surgery, as a method of breast conservation therapy, can be used to treat larger breast lesions as compared to standard lumpectomy.
authors: Department of Obstetrics and Gynecology, Otto-von-Guericke University, Magdeburg, Germany. Holm.Eggemann@med.ovgu.de
authors: H
authors: H
authors: Eggemann
authors: A
authors: A
authors: Ignatov
authors: J
authors: J
authors: Krocker
authors: K
authors: K
authors: Neuss
authors: D
authors: D
authors: Elling
authors: J
authors: J
authors: John
authors: S-D
authors: SD
authors: Costa
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001943:Breast Neoplasms / Q000601:surgery*; D018270:Carcinoma, Ductal, Breast / Q000601:surgery*; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000601:surgery*; D005260:Female; D006801:Humans; D016462:Mammaplasty; D015412:Mastectomy, Segmental; D008875:Middle Aged; D017060:Patient Satisfaction; D011788:Quality of Life; D012189:Retrospective Studies