title: [Computer-aided precise resection of pelvic tumor and function reconstruction].
abstract: OBJECTIVE
  To investigate the value of computer-aided design (CAD) in defining the resection boundary, reconstructing the pelvis and hip in patients with pelvis tumors.
  
  
  METHODS
  Between November 2006 and April 2009, 5 cases of pelvis tumors were treated surgically using CAD technology. There were 3 males and 2 females with an average age of 36.4 years (range, 24-62 years). The cause was osteosarcoma, giant cell tumor of bone, and angiosarcoma in 1 case, respectively, and chondrosarcoma in 2 cases. According to the Enneking system for staging benign and malignant musculoskeletal tumors, regions I, I + II, III, IV, and I + IV is in 1 case, respectively. According to the principle of reverse engineering, 5 patients with pelvis tumors were checked with lamellar CT/MRI scanning, whose two-dimensional data were obtained in disease area. The three-dimensional reconstruction of pelvic anatomical model, precise resection boundary of tumor, individual surgical template, individual prosthesis, and surgical simulation were precisely made by computer with CAD software. Based on the proposal of CAD, the bone tumor was resected accurately, and allograft ilium with internal fixation instrument or allogeneic ilium with personalized prosthetic replacement were used to reconstruct the bone defect after tumor was resected.
  
  
  RESULTS
  The operation was successfully performed in 5 cases. The average operation time was 7.9 hours, and the average blood loss was 3 125 mL. Hemorrhage and cerebrospinal fluid leakage occurred in 1 case, respectively, and were cured after debridement. Five patients were followed up from 24 to 50 months (mean, 34.5 months). All patients began non-weight bearing walk with double crutches at 4-6 weeks after operation, and began walk at 3-6 months after operation. Local recurrence developed in 2 patients at 18 months after operation, and resection and radiotherapy were performed. According to International Society of Limb Salvage criteria for curative effectiveness of bone tumor limb salvage, the results were excellent in 2 and good in 3.
  
  
  CONCLUSIONS
  The individual surgical template, individual prosthesis, and surgical simulation by CAD ensure the precision and reliability of pelvis tumors resection. The CAD technology promotes pelvis tumor resection and the reconstruction of pelvis to individual treatment stage, and good curative effectiveness can be obtained.
authors: Department of Overseas Chinese, General Hospital of Guangzhou Command of Chinese PLA, Guangzhou Guangdong 510010, PR China. dhuanwen123@yahoo.com.cn
authors: Huanwen
authors: H
authors: Ding
authors: Can
authors: C
authors: Yi
authors: Qiang
authors: Q
authors: Tu
authors: Hong
authors: H
authors: Wang
authors: Huiliang
authors: H
authors: Liu
authors: Suolin
authors: S
authors: Zeng
authors: Bao
authors: B
authors: Liu
authors: Jianjian
authors: J
authors: Shen
authors: Yingjun
authors: Y
authors: Wang
mesh_terms: D000328:Adult; D001859:Bone Neoplasms / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012516:Osteosarcoma / Q000601:surgery; D010386:Pelvic Neoplasms / Q000601:surgery*; D019651:Plastic Surgery Procedures / Q000379:methods*; D025321:Surgery, Computer-Assisted; D055815:Young Adult