title: Activity of pegylated liposomal doxorubicin for extragenital mullerian adenosarcoma with sarcomatous overgrowth: a case report and a review of the literature.
abstract: A 47-year-old woman was diagnosed with extragenital mullerian adenosarcoma with sarcomatous overgrowth. One month after her initial surgery, the patient developed pelvic recurrence, which was completely excised by surgery. However, one month later, the patient developed further recurrences in her pelvis and upper abdomen. A clinical complete response was achieved with three cycles of liposomal doxorubicin and is currently clinically free of disease. So far, including the present case, 23 cases of extragenital mulleian adenosarcoma have been reported in the English literature. Because of the rarity of the reported cases, there are no treatment guidelines based on a good level of evidence. In the current report, through a literature review, we provide information on the activity of pegylated liposomal doxorubicin for extragenital mullerian adenosarcoma with sarcomatous overgrowth.
authors: Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
authors: M
authors: M
authors: Maeda
authors: S
authors: S
authors: Mabuchi
authors: Y
authors: Y
authors: Matsumoto
authors: T
authors: T
authors: Hisamatsu
authors: H
authors: H
authors: Ohashi
authors: T
authors: T
authors: Kimura
mesh_terms: D000008:Abdominal Neoplasms / Q000188:drug therapy* / Q000473:pathology; D018195:Adenosarcoma / Q000188:drug therapy* / Q000473:pathology; D004317:Doxorubicin / Q000031:analogs & derivatives* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008875:Middle Aged; D018199:Mixed Tumor, Mesodermal / Q000188:drug therapy* / Q000473:pathology; D010386:Pelvic Neoplasms / Q000188:drug therapy* / Q000473:pathology; D011092:Polyethylene Glycols / Q000627:therapeutic use*; D012509:Sarcoma / Q000473:pathology
chemical_list: C506643:liposomal doxorubicin; D011092:Polyethylene Glycols; D004317:Doxorubicin