title: [Streptococcal toxic shock syndrome or Kawasaki disease? Two case studies of children with group A streptococcal pneumonia empyema].
abstract: We report 2 cases of children with group A streptococcus pyogenes pleuropneumonia, in one child associated with Kawasaki disease and in the other with streptococcal toxic shock syndrome. These 2 features, with theoretically well-defined clinical and biological criteria, are difficult to differentiate in clinical practice, however, likely due to their pathophysiological links. In case of clinical doubt, an echocardiography needs to be performed to search for coronary involvement and treatment including intravenous immunoglobulins, and an antibiotic with an anti-toxin effect such as clindamycin has to be started early.
authors: Unité de médecine infantile, CHU Timone-Enfants, Marseille, France.
authors: A
authors: A
authors: Bosland
authors: K
authors: K
authors: Arlaud
authors: C
authors: C
authors: Rousset-Rouvière
authors: V
authors: V
authors: Fouilloux
authors: O
authors: O
authors: Paut
authors: J-C
authors: JC
authors: Dubus
authors: E
authors: E
authors: Bosdure
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002675:Child, Preschool; D002981:Clindamycin / Q000627:therapeutic use; D003937:Diagnosis, Differential; D004359:Drug Therapy, Combination; D016724:Empyema, Pleural / Q000188:drug therapy / Q000382:microbiology*; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D007155:Immunologic Factors / Q000627:therapeutic use; D007223:Infant; D008297:Male; D009080:Mucocutaneous Lymph Node Syndrome / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy; D011018:Pneumonia, Pneumococcal / Q000188:drug therapy / Q000382:microbiology*; D012772:Shock, Septic / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology* / Q000628:therapy; D013290:Streptococcal Infections / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy / Q000628:therapy; D013297:Streptococcus pyogenes / Q000302:isolation & purification / Q000472:pathogenicity*; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D016756:Immunoglobulins, Intravenous; D007155:Immunologic Factors; D002981:Clindamycin