title: Twist does a twist to the reactivity: stoichiometric and catalytic oxidations with twisted tetramethyl-IBX.
abstract: The methyl groups in TetMe-IBX lower the activation energy corresponding to the rate-determining hypervalent twisting (theoretical calculations), and the steric relay between successive methyl groups twists the structure, which manifests in significant solubility in common organic solvents. Consequently, oxidations of alcohols and sulfides occur at room temperature in common organic solvents. In situ generation of the reactive TetMe-IBX from its precursor iodo-acid, i.e., 3,4,5,6-tetramethyl-2-iodobenzoic acid, in the presence of oxone as a co-oxidant facilitates the oxidation of diverse alcohols at room temperature.
authors: Department of Chemistry, Indian Institute of Technology, Kanpur 208016, India. moorthy@iitk.ac.in
authors: Jarugu Narasimha
authors: JN
authors: Moorthy
authors: Kalyan
authors: K
authors: Senapati
authors: Keshaba Nanda
authors: KN
authors: Parida
authors: Samik
authors: S
authors: Jhulki
authors: Kunnikuruvan
authors: K
authors: Sooraj
authors: Nisanth N
authors: NN
authors: Nair