title: Isolation and chemical characterization of a toxin isolated from the venom of the sea snake, Hydrophis torquatus aagardi.
abstract: Sea snakes (family: Hydrophiidae) are serpents found in the coastal areas of the Indian and Pacific Oceans. There are two subfamilies in Hydrophiidae: Hydrophiinae and Laticaudinae. A toxin, aagardi toxin, was isolated from the venom of the Hydrophiinae snake, Hydrophis torquatus aagardi and its chemical properties such as molecular weight, isoelectric point, importance of disulfide bonds, lack of enzymatic activity and amino acid sequence were determined. The amino acid sequence indicated a close relationship to the primary structure of other Hydrophiinae toxins and a significant difference from Laticaudinae toxins, confirming that primary toxin structure is closely related to sea snake phylogenecity.
authors: Department of Microbiology, Faculty of Pharmacy, Meijo University, Nagoya 468-8503, Japan.
authors: Masaya
authors: M
authors: Nagamizu
authors: Yumiko
authors: Y
authors: Komori
authors: Kei-Ichi
authors: K
authors: Uchiya
authors: Toshiaki
authors: T
authors: Nikai
authors: Anthony T
authors: AT
authors: Tu
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D004546:Elapid Venoms / Q000737:chemistry; D017815:Elapidae; D014118:Toxins, Biological
chemical_list: D004546:Elapid Venoms; D014118:Toxins, Biological