title: Evaluation of intraventricular hemorrhage in pediatric intracerebral hemorrhage.
abstract: Previous studies of pediatric intracerebral hemorrhage have investigated isolated intraparenchymal hemorrhage. The authors investigated whether detailed assessment of intraventricular hemorrhage enhanced outcome prediction after intracerebral hemorrhage. They prospectively enrolled 46 children, full-term to 17 years, median age 2.7 years, with spontaneous intraparenchymal hemorrhage and/or intraventricular hemorrhage. Outcome was assessed with the King's Outcome Scale for Childhood Head Injury. Twenty-six (57%) had intraparenchymal hemorrhage, 10 (22%) had pure intraventricular hemorrhage, and 10 (22%) had both. There were 2 deaths, both with intraparenchymal hemorrhage and intraventricular hemorrhage volume ≥4% of total brain volume. Presence of intraventricular hemorrhage was not associated with poor outcome, but hydrocephalus showed a trend (P = .09) toward poor outcome. In receiver operating characteristic curve analysis, combined intraparenchymal hemorrhage and intraventricular hemorrhage volume also showed a trend toward better outcome prediction than intraparenchymal hemorrhage volume alone. Although not an independent outcome predictor, future studies should assess intraventricular hemorrhage qualitatively and quantitatively.
authors: Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
authors: Jonathan T
authors: JT
authors: Kleinman
authors: Lauren A
authors: LA
authors: Beslow
authors: Kyle
authors: K
authors: Engelmann
authors: Sabrina E
authors: SE
authors: Smith
authors: Daniel J
authors: DJ
authors: Licht
authors: Rebecca N
authors: RN
authors: Ichord
authors: Lori C
authors: LC
authors: Jordan
mesh_terms: D000293:Adolescent; D000367:Age Factors; D002543:Cerebral Hemorrhage / Q000175:diagnosis* / Q000000981:diagnostic imaging; D002552:Cerebral Ventricles / Q000002:abnormalities / Q000473:pathology* / Q000503:physiopathology*; D014695:Cerebral Ventriculography; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D017063:Outcome Assessment, Health Care; D011379:Prognosis; D014057:Tomography, X-Ray Computed