title: Nutritional assessment in patients with pulmonary nontuberculous mycobacteriosis.
abstract: OBJECTIVE
  To determine the nutritional factors that influence disease spread in patients with pulmonary Mycobacterium avium complex (MAC) infection.
  
  
  METHODS
  A prospective observational study.
  
  
  METHODS
  Patients with pulmonary MAC infection were enrolled in this study. Chest computed tomography (CT), abdominal CT, and physical, clinical, and nutritional laboratory data were collected after obtaining informed consent.
  
  
  RESULTS
  Seventy-eight patients (16 males and 62 females) were consecutively enrolled. While the mean body mass index (BMI) was low (19.6 ± 2.7 kg/m(2)), the mean serum albumin concentration was within normal range (4.2 ± 0.2 g/dL). We evaluated the number of affected lung segments to define the degree of disease spread, and examined the relationships between various parameters and disease spread. Multivariate analysis identified the duration of the disease (+1.6 segment/100 months, p=0.03), BMI (-0.5 segment/BMI, p=0.003), and white blood cell count (+0.7 segment/1,000 WBC, p=0.03) as factors contributing to disease spread.
  
  
  CONCLUSIONS
  BMI is an excellent marker for nutritional assessment and for predicting disease spread in patients with pulmonary MAC infection.
authors: National Hospital Organization Omuta National Hospital, Japan. ikegame-s@oomuta-h.com
authors: Satoshi
authors: S
authors: Ikegame
authors: Sanae
authors: S
authors: Maki
authors: Kentaro
authors: K
authors: Wakamatsu
authors: Nobuhiko
authors: N
authors: Nagata
authors: Hiroyuki
authors: H
authors: Kumazoe
authors: Masaki
authors: M
authors: Fujita
authors: Yoichi
authors: Y
authors: Nakanishi
authors: Masayuki
authors: M
authors: Kawasaki
authors: Akira
authors: A
authors: Kajiki
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001835:Body Weight / Q000502:physiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015269:Mycobacterium avium Complex; D015270:Mycobacterium avium-intracellulare Infection / Q000175:diagnosis / Q000453:epidemiology* / Q000503:physiopathology*; D015596:Nutrition Assessment; D011446:Prospective Studies; D012141:Respiratory Tract Infections / Q000175:diagnosis / Q000453:epidemiology* / Q000503:physiopathology*