title: Long term outcomes in patients with preoperative generalized interictal epileptiform abnormalities following amygdalohippocampectomy.
abstract: We evaluated long term surgical outcomes in 21 patients with temporal lobe epilepsy and presurgical generalized interictal epileptiform discharges (IEDs). Following amygdalohippocampectomy, 12 patients (57.1%) were noted to have favorable outcomes (Engel classification of I-II). Favorable outcomes were significantly associated with a history of auras prior to seizure onset (p=0.021), the absence of generalized IEDs on postoperative EEG (p=0.024), and the presence of focal slowing on postoperative EEG (p=0.045).
authors: Department of Neurology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA. moseley.brian@mayo.edu
authors: Brian D
authors: BD
authors: Moseley
authors: Shobhit
authors: S
authors: Sinha
authors: Fredric B
authors: FB
authors: Meyer
authors: W Richard
authors: WR
authors: Marsh
authors: Jeffrey W
authors: JW
authors: Britton
mesh_terms: D000293:Adolescent; D000328:Adult; D000679:Amygdala / Q000601:surgery*; D002648:Child; D004569:Electroencephalography / Q000379:methods; D004833:Epilepsy, Temporal Lobe / Q000503:physiopathology* / Q000601:surgery*; D005260:Female; D006624:Hippocampus / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011184:Postoperative Period; D011300:Preoperative Care / Q000379:methods; D012189:Retrospective Studies; D016896:Treatment Outcome; D055815:Young Adult