title: Eosinophilic keratoconjunctivitis in two rabbits.
abstract: The purpose of this case report is to describe the clinical course and cytologic findings, treatment, and outcome of eosinophilic keratoconjunctivitis in two rabbits. Ophthalmic examination revealed ocular discharge, dacryocystitis, blepharitis, conjunctivitis, white conjunctival and corneal plaques, corneal vascularization, and stromal infiltration with different degrees of severity in each case. In case 2 there was also ulcerative disease of the cornea. Computerized tomography scan of the head, corneal biopsy for histopathologic examination with additional Luna and Giemsa stain were performed in case 2 and conjunctival as well as corneal specimens were obtained for bacteriologic culture and cytologic examination in case 1. Based on test results, a diagnosis of eosinophilic keratoconjunctivitis was made in case 2 and a tentative diagnosis of eosinophilic keratoconjunctivitis was made in case 1. Response to treatment with a topical steroid and topical cyclosporin was supportive of the diagnosis in both cases and shared many similarities with the response to treatment previously described in cats. Eosinophilic keratitis should be considered as part of a differential diagnosis list in rabbits with a history of keratitis.
authors: Ophthalmology section, Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands. p.grinninger@uu.nl
authors: Petra
authors: P
authors: Grinninger
authors: Rick
authors: R
authors: Sanchez
authors: Ingrid M G
authors: IM
authors: Kraijer-Huver
authors: Willem-Jan P
authors: WJ
authors: Kitslaar
authors: Nico J
authors: NJ
authors: Schoemaker
authors: Guy C M
authors: GC
authors: Grinwis
authors: Michael H
authors: MH
authors: Boevé
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use; D004338:Drug Combinations; D004802:Eosinophilia / Q000473:pathology / Q000628:therapy / Q000662:veterinary*; D005260:Female; D007166:Immunosuppressive Agents / Q000008:administration & dosage / Q000627:therapeutic use; D007637:Keratoconjunctivitis / Q000188:drug therapy / Q000473:pathology / Q000662:veterinary*; D008297:Male; D011817:Rabbits
chemical_list: D000900:Anti-Bacterial Agents; D004338:Drug Combinations; D007166:Immunosuppressive Agents