title: [Neuropsychological impairment in Parkinson's disease without dementia].
abstract: Cognitive dysfunction in Parkinson's Disease (PD) has been consistently reported, but little is known about cognitive impairment in PD patients without dementia, and its association with clinical characteristics, neuropsychiatric disturbance and functional activities. Therefore, we evaluated 52 non-demented PD patients, 22 of them with mild cognitive impairment (PD-MCI) who were matched with 52 healthy controls. Our results confirm the existence of dysfunction in information processing speed, executive function, verbal memory and visuo-perceptual processing in PD. On the other hand, PD-MCI was associated with advanced age at the onset of PD, more neuropsychiatric symptoms, caregiver stress and functional problems. The study supports the hypothesis that specific neuropsychological impairments may act as modulators of functional impairment in PD, for instance slowness of information processing.
authors: Facultad de Psicología y Educación, Universidad de Deusto, 48007 Bilbao, Spain. danimaranon@hotmail.com
authors: Daniel
authors: D
authors: Marañón
authors: Imanol
authors: I
authors: Amayra
authors: Juan María
authors: JM
authors: Uterga
authors: Juan Carlos
authors: JC
authors: Gómez-Esteban
mesh_terms: D000368:Aged; D003072:Cognition Disorders / Q000209:etiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D010300:Parkinson Disease / Q000150:complications* / Q000523:psychology*