title: In situ mechanical analysis of cardiomyocytes at nano scales.
abstract: Nanomechanical behaviors of single living cardiomyocytes are quantitatively observed using calculated torsions and deflections of an AFM cantilever. The lateral contractions are related to the calcium intensity within rather than the vertical beating power of the cardiomyocytes. Drug-induced nanomechanical changes of cardiomyocytes were further investigated by measuring lateral contractions in real time.
authors: Emergency Department, Peking University People's Hospital, Beijing 100044, People's Republic of China.
authors: Yuansheng
authors: Y
authors: Liu
authors: Jiantao
authors: J
authors: Feng
authors: Liang
authors: L
authors: Shi
authors: Ruibin
authors: R
authors: Niu
authors: Quanmei
authors: Q
authors: Sun
authors: Hao
authors: H
authors: Liu
authors: Jing
authors: J
authors: Li
authors: Jihong
authors: J
authors: Guo
authors: Jihong
authors: J
authors: Zhu
authors: Dong
authors: D
authors: Han
mesh_terms: D000818:Animals; D002118:Calcium / Q000378:metabolism; D018625:Microscopy, Atomic Force; D008856:Microscopy, Fluorescence; D032383:Myocytes, Cardiac / Q000166:cytology* / Q000378:metabolism; D049329:Nanostructures / Q000737:chemistry; D051381:Rats
chemical_list: D002118:Calcium