title: Productivity enhancement of C=C bioreductions by coupling the in situ substrate feeding product removal technology with isolated enzymes.
abstract: To overcome the usually low productivities of the C=C bond bioreduction of α,β-unsaturated aldehydes we combined the in situ substrate feeding product removal (SFPR) technology with a cascade system comprising an isolated ene-reductase and a chemoselective alcohol dehydrogenase.
authors: Politecnico di Milano, Department of Chemistry, Materials and Chemical Engineering Giulio Natta, Piazza Leonardo Da Vinci 32, 20131, Milano, Italy.
authors: Elisabetta
authors: E
authors: Brenna
authors: Francesco G
authors: FG
authors: Gatti
authors: Daniela
authors: D
authors: Monti
authors: Fabio
authors: F
authors: Parmeggiani
authors: Alessandro
authors: A
authors: Sacchetti
mesh_terms: D000426:Alcohol Dehydrogenase / Q000302:isolation & purification / Q000378:metabolism*; D000447:Aldehydes / Q000737:chemistry* / Q000378:metabolism*; D002244:Carbon / Q000737:chemistry*; D010084:Oxidation-Reduction; D010088:Oxidoreductases / Q000302:isolation & purification / Q000378:metabolism*; D012441:Saccharomyces cerevisiae / Q000201:enzymology
chemical_list: D000447:Aldehydes; D002244:Carbon; D010088:Oxidoreductases; D000426:Alcohol Dehydrogenase