title: The application of multiplexed assay systems for molecular diagnostics.
abstract: For decades, the diagnosis of schizophrenia and other psychiatric disorders has relied on subjective assessments such as Diagnostic and Statistical Manual criteria. There is now increasing interest in the identification of altered molecular patterns in blood and other accessible body fluids that can be used to help identify, stratify, and monitor psychiatric patients. Since shorter periods of psychosis are associated with a better prognosis, an accurate molecular test may lead to early intervention and thereby improve patient outcomes. In addition, such a test would open up the possibility to stratify more accurately the disease and could represent a novel translational medicine tool, which is crucial for the discovery and development of more efficacious therapies.
authors: Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, United Kingdom.
authors: Emanuel
authors: E
authors: Schwarz
authors: Nico J M
authors: NJ
authors: VanBeveren
authors: Paul C
authors: PC
authors: Guest
authors: Rauf
authors: R
authors: Izmailov
authors: Sabine
authors: S
authors: Bahn
mesh_terms: D001681:Biological Assay / Q000379:methods* / Q000639:trends; D015415:Biomarkers / Q000032:analysis* / Q000097:blood; D006801:Humans; D025202:Molecular Diagnostic Techniques / Q000379:methods* / Q000639:trends; D019965:Neurocognitive Disorders / Q000175:diagnosis* / Q000378:metabolism*; D058027:Neuropsychiatry / Q000379:methods / Q000639:trends; D011237:Predictive Value of Tests; D057170:Translational Research, Biomedical / Q000379:methods / Q000639:trends
chemical_list: D015415:Biomarkers