title: Ecological-level associations between highly processed food intakes and plasma phospholipid elaidic acid concentrations: results from a cross-sectional study within the European prospective investigation into cancer and nutrition (EPIC).
abstract: Elaidic acid is the main unnatural trans fatty acid isomer occurring during partial hydrogenation of vegetable oils used as ingredients for the formulation of processed foods. The main objective is to assess associations between processed food intakes and plasma phospholipid elaidic acid concentrations within the European Prospective Investigation into Cancer and Nutrition study. A cross-sectional study was used to determine fatty acid profiles in 3,003 subjects from 16 centers. Single 24-h dietary recalls (24-HDR) were collected using a standardized computerized interview program. Food intakes were computed according to their degree of processing (moderately/nonprocessed foods, processed staple foods, highly processed foods). Adjusted ecological and individual correlations were calculated between processed food intakes and plasma elaidic acid levels. At the population level, mean intakes of highly processed foods were strongly correlated with mean levels of plasma elaidic acid in men (P = 0.0016) and in women (P = 0.0012). At the individual level, these associations remained but at a much lower level in men (r = 0.08, P = 0.006) and in women (r = 0.09, P = 0.0001). The use of an averaged 24-HDR measure of highly processed food intakes is adequate for predicting mean levels of plasma elaidic acid among European populations.
authors: The International Agency for Research on Cancer, Lyon, France.
authors: Véronique
authors: V
authors: Chajès
authors: Carine
authors: C
authors: Biessy
authors: Graham
authors: G
authors: Byrnes
authors: Geneviève
authors: G
authors: Deharveng
authors: Mitra
authors: M
authors: Saadatian-Elahi
authors: Mazda
authors: M
authors: Jenab
authors: Petra H M
authors: PH
authors: Peeters
authors: Marga
authors: M
authors: Ocké
authors: H Bas
authors: HB
authors: Bueno-de-Mesquita
authors: Ingegerd
authors: I
authors: Johansson
authors: Göran
authors: G
authors: Hallmans
authors: Jonas
authors: J
authors: Manjer
authors: Elisabet
authors: E
authors: Wirfält
authors: Paula
authors: P
authors: Jakszyn
authors: Carlos A
authors: CA
authors: González
authors: Jose-Maria
authors: JM
authors: Huerta
authors: Carmen
authors: C
authors: Martinez
authors: Pilar
authors: P
authors: Amiano
authors: Laudina Rodriguez
authors: LR
authors: Suárez
authors: Eva
authors: E
authors: Ardanaz
authors: Anne
authors: A
authors: Tjønneland
authors: Jytte
authors: J
authors: Halkjaer
authors: Kim
authors: K
authors: Overvad
authors: Marianne Uhre
authors: MU
authors: Jakobsen
authors: Franco
authors: F
authors: Berrino
authors: Valeria
authors: V
authors: Pala
authors: Domenico
authors: D
authors: Palli
authors: Rosario
authors: R
authors: Tumino
authors: Paolo
authors: P
authors: Vineis
authors: Maria Santucci
authors: MS
authors: de Magistris
authors: Elisabeth A
authors: EA
authors: Spencer
authors: Francesca L
authors: FL
authors: Crowe
authors: Sheila
authors: S
authors: Bingham
authors: Kay-Tee
authors: KT
authors: Khaw
authors: Jakob
authors: J
authors: Linseisen
authors: Sabine
authors: S
authors: Rohrmann
authors: Heiner
authors: H
authors: Boeing
authors: Ute
authors: U
authors: Nöethlings
authors: Karina Standahl
authors: KS
authors: Olsen
authors: Guri
authors: G
authors: Skeie
authors: Eiliv
authors: E
authors: Lund
authors: Antonia
authors: A
authors: Trichopoulou
authors: Dimosthenis
authors: D
authors: Zilis
authors: Erifili
authors: E
authors: Oustoglou
authors: Françoise
authors: F
authors: Clavel-Chapelon
authors: Elio
authors: E
authors: Riboli
authors: Nadia
authors: N
authors: Slimani
mesh_terms: D015331:Cohort Studies; D003430:Cross-Sectional Studies; D004041:Dietary Fats / Q000008:administration & dosage / Q000097:blood; D002149:Energy Intake; D005060:Europe; D057140:Fast Foods; D005227:Fatty Acids / Q000008:administration & dosage / Q000097:blood; D005247:Feeding Behavior; D005260:Female; D005511:Food Handling / Q000379:methods; D006801:Humans; D007407:Interviews as Topic; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D009369:Neoplasms / Q000473:pathology; D009749:Nutrition Surveys; D019301:Oleic Acid / Q000097:blood*; D009829:Oleic Acids; D010743:Phospholipids / Q000097:blood*; D011795:Surveys and Questionnaires
chemical_list: D004041:Dietary Fats; D005227:Fatty Acids; D009829:Oleic Acids; D010743:Phospholipids; D019301:Oleic Acid; C011459:elaidic acid