title: Effect of bariatric surgery on obesity-related infertility.
abstract: BACKGROUND
  There is a strong association between obesity and infertility, and weight loss can increase fecundity in obese women. In an attempt to determine the effect of bariatric surgery on obesity-related infertility, we reviewed the fertility outcomes after intragastric balloon placement, adjustable gastric banding, sleeve gastrectomy, and gastric bypass in childbearing women with a diagnosis of infertility at a university hospital in Italy.
  
  
  METHODS
  This was a retrospective study of 110 obese infertile women. We evaluated the effectiveness of bariatric surgery in improving fertility, assessing the influence of age, surgical technique, co-morbidities (hypertension and diabetes), weight loss, and body mass index before and after surgery.
  
  
  RESULTS
  Of these 110 women who had tried unsuccessfully to become pregnant before weight loss, 69 became pregnant afterward. The pregnancies proceeded without complications and ended with a live birth. Only the weight loss (odds ratio 20.2, P = .001) and the achieved body mass index (P = .001) after surgery were the predictors of pregnancy.
  
  
  CONCLUSIONS
  Bariatric surgery might be effective in young infertile obese women who wish to become pregnant. Weight loss appears to be independent from the surgical technique in determining the increase in the pregnancy rate as well as the body mass index achieved at pregnancy.
authors: Department of Surgery, Orthopedic, Traumatology, and Emergency, University of Naples Federico II, Naples, Italy.
authors: Mario
authors: M
authors: Musella
authors: Marco
authors: M
authors: Milone
authors: Marcello
authors: M
authors: Bellini
authors: Loredana Maria
authors: LM
authors: Sosa Fernandez
authors: Maddalena
authors: M
authors: Leongito
authors: Francesco
authors: F
authors: Milone
mesh_terms: D000328:Adult; D050110:Bariatric Surgery / Q000379:methods*; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000209:etiology / Q000601:surgery*; D009767:Obesity, Morbid / Q000150:complications / Q000601:surgery*; D016742:Preconception Care / Q000379:methods; D011247:Pregnancy; D018873:Pregnancy Rate; D012189:Retrospective Studies; D015431:Weight Loss