title: Plexiform angiomyxoid myofibroblastic tumor of the stomach: a case report.
abstract: Plexiform angiomyxoid myofibroblastic tumor (PAMT) is a recently described mesenchymal tumor of the stomach. We report the first case of PAMT in Korea. A 52-yr-old man underwent esophagogastroduodenoscopy due to dyspepsia for 2 yr. There was a submucosal mass with small mucosal ulceration in the gastric antrum. The tumor measured 3.5 × 2.3 cm in size and showed multinodular plexiform growth pattern of bland-looking spindle cells separated by an abundant myxoid or fibromyxoid matrix rich in small thin-walled blood vessels. The tumor cells were negative for CD117 (c-KIT), CD34 and S-100 protein, but diffusely positive for smooth muscle actin consistent with predominant myofibroblastic differentiation. The patient is doing well without recurrence or metastasis for 5 months after surgery. Although there have been limited follow-up data, PAMT is regarded as a benign gastric neoplasm with histological and immunohistochemical characteristics distinguished from gastrointestinal stromal tumor and other mesenchymal tumors of the stomach.
authors: Department of Pathology, Yeungnam University College of Medicine, Daegu, Korea.
authors: Aeri
authors: A
authors: Kim
authors: Young Kyung
authors: YK
authors: Bae
authors: Hyeong Chan
authors: HC
authors: Shin
authors: Joon Hyuk
authors: JH
authors: Choi
mesh_terms: D004415:Dyspepsia / Q000175:diagnosis; D016145:Endoscopy, Digestive System; D006801:Humans; D008297:Male; D008875:Middle Aged; D058628:Myofibroblasts; D009232:Myxoma / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D011706:Pyloric Antrum / Q000473:pathology; D013274:Stomach Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000601:surgery