title: [Rubrofusarin glucosides of Berchemia polyphylla var. leioclada and their scavenging activities for DPPH radical].
abstract: OBJECTIVE
  To study the rubrofusarin glucosides from whole plants of Berchemia polyphylla var. leioclada, and their scavenging activities for 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical.
  
  
  METHODS
  The chemical constituents were isolated and purified via repeated silica gel and Sephadex LH-20 column chromatography. Their structures were elucidated by spectral analysis and the compounds were tested for their scavenging activities on DPPH radical.
  
  
  RESULTS
  Three rubrofusarin glucosides compounds were isolated and identified as rubrofusarin-6-O-beta-D-glucopyranoside (1), rubrofusarin-6-O-beta-D-(6'-O-acetyl) glucopyranoside (2), rubrofusarin-6-O-alpha-L-rhamnosyl-(1-6) -O-beta-D-glucopyranside (3). Three isolated compounds showed strong scavenging activities on DPPH radical, the concentration of half elimination ratio( micromol x L(-1)) of VitC and Compounds 1-3 were 18.2, 40.5, 23.3 and 13.6, respectively.
  
  
  CONCLUSIONS
  Compounds 1-3 were isolated from this plant for the first time and compound 2 was a new compound. They showed significant antioxidant activity, and the scavenging activity of compound 3 was a little stronger than that of VitC.
authors: The Key Laboratory of Chemistry for Natural Products, Chinese Academy of Sciences, Guiyang 550002, China. cjys1985@126.com
authors: Yongshuai
authors: Y
authors: Jing
authors: Juan
authors: J
authors: Yang
authors: Lanfang
authors: L
authors: Wu
authors: Zhendong
authors: Z
authors: Zhang
authors: Li
authors: L
authors: Fang
mesh_terms: D001713:Biphenyl Compounds / Q000378:metabolism*; D016166:Free Radical Scavengers / Q000737:chemistry* / Q000494:pharmacology; D005960:Glucosides / Q000737:chemistry* / Q000494:pharmacology*; D019906:Nuclear Magnetic Resonance, Biomolecular; D010851:Picrates / Q000378:metabolism*; D011753:Pyrones / Q000737:chemistry* / Q000494:pharmacology*; D027823:Rhamnaceae / Q000737:chemistry*
chemical_list: D001713:Biphenyl Compounds; D016166:Free Radical Scavengers; D005960:Glucosides; D010851:Picrates; D011753:Pyrones; C015497:rubrofusarin; C004931:1,1-diphenyl-2-picrylhydrazyl