title: Determination of peritoneal membrane transport characteristics with dialysis adequacy and transport test in Thai patients.
abstract: OBJECTIVE
  The characteristics of peritoneal membrane transport are useful for the determination of dialysis treatment prescription. The peritoneal equilibration test (PET) is accepted as a gold standard tool for identification of these characteristics. Unfortunately, the process of PET is troublesome and unsuitable for clinical practice. Dialysis adequacy and transport test (DATT), which is easier and more convenient method, is proposed as an alternative test. The aim of the present study was to evaluate the accuracy of the DATT in determination of membrane characteristics in Thai patients.
  
  
  METHODS
  Fifteen patients underwent both DATT and PET on the same day. The second DATT was performed. The 24-hour dialysate-to-plasma ratio of creatinine (D/Pcr) from each DATT was compared with the adjusted 4-hour D/Pcr from the corresponding PET. The types of membrane solute transport were classified using the PET proposed by Twardowski and the DATT suggested by Rocco into high, high average, low average, and low transporter
  
  
  RESULTS
  The mean age was 48.1 +/- 16.4 years. The mean value of D/Pcr derived from DATT was higher than PET (0.80 +/- 0.10 vs. 0.74 +/- 0.14). The results of both D/Pcr were correlated (r = 0.78, p = 0.001). However, determinations of characteristics of membrane transport were discordant (kappa coefficient = 0.25). The results of the repeated D/Pcr were not different and the classification of membrane transport properties were concordant (kappa coefficient = 0.68).
  
  
  CONCLUSIONS
  The results of D/Pcr derived from both tests were correlated. However determinations of characteristics of membrane transport were discordant.
authors: Division of Medicine, Hat Yai Hospital, Songkhla, Thailand. kcharoen007@hotmail.com
authors: Charoen
authors: C
authors: Kaitwatcharachai
authors: Jaruda
authors: J
authors: Aden
authors: Khamanut
authors: K
authors: Kongkid
authors: Tharntip
authors: T
authors: Kitpiboonchai
authors: Somthawil
authors: S
authors: Kaitwatcharachai
mesh_terms: D000328:Adult; D000368:Aged; D044466:Asian People; D001692:Biological Transport; D003404:Creatinine / Q000032:analysis / Q000378:metabolism; D015314:Dialysis Solutions / Q000032:analysis*; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000378:metabolism / Q000628:therapy*; D007677:Kidney Function Tests / Q000379:methods*; D008297:Male; D008875:Middle Aged; D010531:Peritoneal Dialysis, Continuous Ambulatory; D010537:Peritoneum / Q000737:chemistry / Q000378:metabolism*; D011237:Predictive Value of Tests; D012680:Sensitivity and Specificity; D013785:Thailand; D055815:Young Adult
chemical_list: D015314:Dialysis Solutions; D003404:Creatinine