title: Photocrosslinkable polyesters and poly(ester anhydride)s for biomedical applications.
abstract: Crosslinking is a feasible way to prepare biodegradable polymers with potential in biomedical applications such as controlled release of active agents and tissue engineering. A synthesis route in which functional telechelic aliphatic polyester oligomers are used as precursors for the preparation of crosslinked polyesters and poly(ester anhydride)s is described. Mechanical properties, degradation characteristics and rate, and bioactivity can be modified widely by controlling the chemical composition and architecture of the crosslinkable oligomers. In tissue engineering, photocrosslinking allows to use crosslinkable oligomers in advanced manufacturing techniques like micromolding in capillaries, stereolithography and two-photon polymerization.
authors: Polymer Technology, School of Chemical Technology, Department of Biotechnology and Chemical Technology, Aalto University, PO Box 16100, FI-00076 Aalto, Finland. jukka.seppala@aalto.fi
authors: Jukka
authors: J
authors: Seppälä
authors: Harri
authors: H
authors: Korhonen
authors: Risto
authors: R
authors: Hakala
authors: Minna
authors: M
authors: Malin
mesh_terms: D001672:Biocompatible Materials / Q000138:chemical synthesis / Q000737:chemistry; D001673:Biodegradation, Environmental; D003692:Delayed-Action Preparations / Q000138:chemical synthesis / Q000737:chemistry; D055668:Photochemical Processes; D017785:Photons; D011091:Polyesters / Q000032:analysis / Q000138:chemical synthesis*; D058105:Polymerization; D017550:Spectroscopy, Fourier Transform Infrared; D023822:Tissue Engineering / Q000379:methods
chemical_list: D001672:Biocompatible Materials; D003692:Delayed-Action Preparations; D011091:Polyesters