title: Comparison of treatments with the Forsus fatigue resistant device in relation to skeletal maturity: a cephalometric and magnetic resonance imaging study.
abstract: BACKGROUND
  The aim of this study was to compare the dentoskeletal changes and alterations of mandibular condyle-disc-fossa relationships in subjects at the peak and the end of the pubertal growth period treated with the Forsus fatigue resistant device (3M Unitek, Monrovia, Calif).
  
  
  METHODS
  The sample consisted of 29 subjects with Class II Division 1 malocclusions who were classified according to their hand-wrist radiographs. Fifteen patients were at or just before the peak phase of pubertal growth (peak pubertal group). Fourteen patients were near the end of the pubertal growth period (late pubertal group). The study was conducted by using lateral cephalometric radiographs and magnetic resonance images obtained at the beginning and at the end of the application of the Forsus fatigue resistant device. The treatment period was 9 months.
  
  
  RESULTS
  The Wilcoxon signed rank test was used to evaluate differences within groups. The changes observed in both groups were compared by using the Mann-Whitney U test. There were statistically significant group differences in mandibular length and ramus length, with significant increases of these parameters in the peak pubertal group (P <0.05). No significant differences were observed between the groups concerning dental parameters (P >0.05), with the exception of mandibular molar vertical movements, which were significantly greater in the peak pubertal group (P <0.05). Analysis of the magnetic resonance images showed no positional changes of the mandibular condyle in relation to the glenoid fossa in either group (P >0.05). Although the articular disc was positioned more anteriorly in the peak pubertal group compared with its pretreatment position (P <0.05), the position of the disc was still within the physiologic range. No significant intergroup difference was observed for disc-condyle relationship (P >0.05).
  
  
  CONCLUSIONS
  The Forsus fatigue resistant device did not appear to cause significant increases in mandibular dimensions in subjects in late puberty. According to the magnetic resonance image findings, Forsus treatment is not a risk factor for the development of temporomandibular dysfunction in subjects with no signs and clinical symptoms of dysfunction.
authors: Department of Orthodontics, Faculty of Dentistry, Ege University, Izmir, Turkey. aynuraras@yahoo.com
authors: Aynur
authors: A
authors: Aras
authors: Emel
authors: E
authors: Ada
authors: Hatice
authors: H
authors: Saracoğlu
authors: Naciye S
authors: NS
authors: Gezer
authors: Isil
authors: I
authors: Aras
mesh_terms: D000293:Adolescent; D000365:Age Determination by Skeleton; D001846:Bone Development / Q000502:physiology*; D002508:Cephalometry / Q000379:methods*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008312:Malocclusion, Angle Class II / Q000628:therapy; D008334:Mandible / Q000254:growth & development / Q000473:pathology; D008335:Mandibular Condyle / Q000254:growth & development / Q000473:pathology; D008963:Molar / Q000473:pathology; D016382:Orthodontic Appliance Design; D009967:Orthodontic Appliances; D016910:Orthodontic Brackets; D009969:Orthodontic Wires; D011627:Puberty / Q000502:physiology; D016059:Range of Motion, Articular / Q000502:physiology; D063173:Retrognathia / Q000628:therapy; D013701:Temporal Bone / Q000254:growth & development / Q000473:pathology; D013704:Temporomandibular Joint / Q000254:growth & development / Q000473:pathology; D019224:Temporomandibular Joint Disc / Q000254:growth & development / Q000473:pathology