title: Primary hyperparathyroidism - is vitamin D supplementation safe?
abstract: BACKGROUND
  Vitamin D deficiency is commonly seen in patients with primary hyperparathyroidism. However, there is a widespread reluctance to provide vitamin D supplementation to this group of patients.
  
  
  OBJECTIVE
  This article examines the relationship between vitamin D deficiency and primary hyperparathyroidism and the effects of vitamin D supplementation.
  
  
  CONCLUSIONS
  Vitamin D deficiency exacerbates primary hyperparathyroidism and vice versa. With care, vitamin D supplementation can safely be given to selected patients with asymptomatic primary hyperparathyroidism and is suggested before deciding on medical or surgical management. Monitoring serum calcium concentration and urinary calcium excretion is recommended while achieving vitamin D repletion.
authors: Division of Medicine, Flinders Medical Centre, Bedford Park, South Australia. wayne.rankin@health.sa.gov.au
authors: Wayne
authors: W
authors: Rankin
mesh_terms: D019587:Dietary Supplements; D006801:Humans; D049950:Hyperparathyroidism, Primary / Q000097:blood / Q000209:etiology / Q000517:prevention & control; D012307:Risk Factors; D014807:Vitamin D / Q000009:adverse effects / Q000493:pharmacokinetics*; D014808:Vitamin D Deficiency / Q000097:blood / Q000150:complications / Q000188:drug therapy; D014815:Vitamins / Q000009:adverse effects / Q000493:pharmacokinetics
chemical_list: D014815:Vitamins; D014807:Vitamin D