title: Antimicrobial flavonoids from Tridax procumbens.
abstract: Callus culture of Tridax procumbens has been established on Murashige and Skoog's medium supplemented with NAA and BAP from nodal segments. Free and bound flavonoids were extracted from 2, 4, 6 and 8 weeks old calli by a well-established method. These free flavonoids were then screened against Staphylococcus aureus (bacteria) and Candida albicans (yeast) for their antimicrobial potential. Minimum inhibitory concentration, minimum bactericidal/fungicidal concentrations and total activity were also evaluated. Apigenin, quercetin and kaempferol were identified from free flavonoids of 4 weeks old callus (most active) through, thin layer chromatography, (TLC) preparative TLC, MP and IR spectral studies.
authors: Laboratory of Plant Tissue Culture and Secondary Metabolites, Department of Botany, University of Rajasthan, Jaipur, India. jindal4@gmail.com
authors: Alka
authors: A
authors: Jindal
authors: Padma
authors: P
authors: Kumar
mesh_terms: D000890:Anti-Infective Agents / Q000737:chemistry / Q000494:pharmacology*; D047310:Apigenin / Q000737:chemistry / Q000494:pharmacology; D002176:Candida albicans / Q000187:drug effects; D002855:Chromatography, Thin Layer; D005419:Flavonoids / Q000737:chemistry / Q000494:pharmacology*; D044949:Kaempferols / Q000737:chemistry / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D011794:Quercetin / Q000737:chemistry / Q000494:pharmacology; D013211:Staphylococcus aureus / Q000187:drug effects
chemical_list: D000890:Anti-Infective Agents; D005419:Flavonoids; D044949:Kaempferols; C006552:kaempferol; D047310:Apigenin; D011794:Quercetin