title: Respiratory involvement in the gastroesophageal reflux disesease.
abstract: The pathological gastroesophageal reflux disease may lead to the gastroesophageal reflux disease (GERD), manifested as a spectrum of conditions including erosive esophagitis, Barrett esophagus and has been linked to the development of adenocarcinoma of the esophagus. The gastroesophageal reflux has been incriminated in the occurence of a number of pulmonary symptoms and diseases, otolaryngologic symptoms, and other extraesophageal manifestations. Clinicians must be aware of the possibility of some extraesophageal reflux-related manifestations, even in the absence of heartburn and acid reflux, classic esophageal symptoms of GERD. Although the correlation between gastroesophageal reflux disease and the extraesophageal manifestations has been established, a cause-and-effect relationship has not been proved yet. In this article, we present the respiratory manifestations of gastroesophageal reflux disease, referring to epidemiology, pathogenesis, diagnosis and treatment.
authors: University of Medicine and Pharmacy Iuliu Hatieganu Cluj-Napoca, Romania, 2nd Medical Dept.
authors: Iulia
authors: I
authors: Mureşan
authors: Alina
authors: A
authors: Picos
authors: Simona
authors: S
authors: Grad
authors: D L
authors: DL
authors: Dumitrascu
mesh_terms: D001249:Asthma / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology* / Q000628:therapy; D002908:Chronic Disease; D003371:Cough / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology / Q000209:etiology*; D003937:Diagnosis, Differential; D019317:Evidence-Based Medicine; D018662:Fundoplication; D005745:Gastric Acidity Determination; D005764:Gastroesophageal Reflux / Q000150:complications* / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy; D006801:Humans; D007827:Laryngitis / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology* / Q000628:therapy; D015995:Prevalence; D011379:Prognosis; D054328:Proton Pump Inhibitors / Q000627:therapeutic use; D018570:Risk Assessment; D012307:Risk Factors; D012383:Romania / Q000453:epidemiology; D016896:Treatment Outcome
chemical_list: D054328:Proton Pump Inhibitors