title: [Individual management of Meniere's disease and evaluation of functional outcome].
abstract: OBJECTIVE
  To investigate individual management for Meniere's disease and analyze outcomes of nonsurgical and surgical management of Meniere's disease.
  
  
  METHODS
  Patients with Meniere's disease were staged according to hearing and quality of life. The individual management according to the staging was established, including outpatient treatment (lifestyle change, medical management and intratympanic steroids), endolymphatic sac decompression or drainage, vestibular neurectomy and labyrinthectomy. The characteristics of patients who underwent surgical management were analyzed. The functional outcomes of surgery in dizziness, hearing loss and quality of life were evaluated for 12-month postoperative follow-up.
  
  
  RESULTS
  Twenty patients underwent intratympanic injection of dexamethasone. Dizziness improved in 70% (14/20), tinnitus improved in 41% (7/17), and aural fullness improved in 36% (4/11). There were 55 patients who underwent surgical managements for 57 times. Endolymphatic sac decompression or drainage was carried out in 27 patients for 28 times, vestibular neurectomy in 26 patients and labyrinthectomy in 3 patients. Vertigo control rate was 75% in patients with endolymphatic sac decompression or drainage, 100% in vestibular neurectomy and 100% in labyrinthectomy at 12-month postoperative follow-up.
  
  
  CONCLUSIONS
  The non-surgical management and endolymphatic sac decompression or drainage can improve vertigo and ameliorate quality of life. Vestibular neurectomy and labyrinthectomy are effective surgical managements to eliminate vertigo. The management of Meniere's disease depends on several factors: stages of vertigo and hearing, quality of life, surgical contraindications and subjective desire. Therefore, the management for Menieres disease must be individualized for each patient.
authors: Department of Otorhinolaryngology-Head and Neck Surgery, Xinhua Hospital Affiliated Shanghai Jiaotong University School of Medicine, Ear Institute of Shanghai Jiaotong University School of Medicine, Shanghai ,200092, China.
authors: Ying
authors: Y
authors: Chen
authors: Jun
authors: J
authors: Yang
authors: Hao
authors: H
authors: Wu
authors: Qi
authors: Q
authors: Huang
authors: Zhaoyan
authors: Z
authors: Wang
authors: Zhihua
authors: Z
authors: Zhang
mesh_terms: D000328:Adult; D000368:Aged; D004322:Drainage; D005260:Female; D006801:Humans; D008297:Male; D008575:Meniere Disease / Q000601:surgery* / Q000628:therapy*; D008875:Middle Aged; D011788:Quality of Life; D016896:Treatment Outcome; D014717:Vertigo / Q000601:surgery / Q000628:therapy