title: [Silent celiac disease among 21 patients with cryptogenic epilepsy].
abstract: BACKGROUND
  Celiac disease (CD) is predominant in women and young people. Atypical, non-enteric symptoms are more common among adults. There is also an association between CD and neurological disorders, especially with cerebellar ataxia, polyneuropathy and epilepsy.
  
  
  OBJECTIVE
  To study the frequency of CD in a group of adults with cryptogenic epilepsy.
  
  
  METHODS
  Twenty one patients with cryptogenic epilepsy, aged 20 to 65 years (14 women) were studied, measuring IgA-anti transglutaminase antibodies and deamidated gliadin peptide (DGP) IgG and IgA antibodies.
  
  
  RESULTS
  One patient had elevated titers of both types of antibodies. Small bowel biopsy showed villous atrophy and lymphocytic infiltration compatible with CD.
  
  
  CONCLUSIONS
  One of 21 adult patients with cryptogenic epilepsy had a silent CD.
authors: Laboratorio Gastroenterología, Sección de Gastroenterología, Departamento de Medicina Interna, Hospital Clínico Universidad de Chile, Chile. anamariamadrid@gmail.com
authors: Ana María
authors: AM
authors: Madrid S
authors: Mario
authors: M
authors: Díaz S
authors: Carmen
authors: C
authors: Hurtado H
authors: Ledda
authors: L
authors: Aguilera O
authors: Boris
authors: B
authors: Mena U
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000888:Antibodies, Anti-Idiotypic / Q000097:blood*; D002446:Celiac Disease / Q000150:complications / Q000175:diagnosis* / Q000276:immunology; D004827:Epilepsy / Q000150:complications*; D005260:Female; D005903:Gliadin / Q000097:blood / Q000276:immunology*; D006801:Humans; D007070:Immunoglobulin A / Q000097:blood / Q000276:immunology; D007074:Immunoglobulin G / Q000097:blood / Q000276:immunology; D008297:Male; D008875:Middle Aged; D011503:Transglutaminases / Q000097:blood / Q000276:immunology*; D055815:Young Adult
chemical_list: D000888:Antibodies, Anti-Idiotypic; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D005903:Gliadin; D011503:Transglutaminases