title: [Renal denervation a new treatment option in resistant arterial hypertension].
abstract: Resistant hypertension is defined as blood pressure that remains above therapeutic goal despite the use of 3 antihypertensive drugs including a diuretic. After exclusion of secondary causes and medical in compliance, the estimated prevalence of resistant arterial hypertension ranges from 4% to 19% in hypertensive patients. Treatment requires a multimodal therapeutic approach. Hyperactivation of the sympathetic nervous system plays a key role in the genesis of hypertension. Targeting renal sympathetic nerves, percutaneous catheter-based renal denervation is a new therapeutic option for the treatment of resistant arterial hypertension in selected drug resistant patients.
authors: Medizinische Klinik II, Universitätsklinikum Schleswig-Holstein, Campus Lübeck. frank.himmel@uk-sh.de
authors: F
authors: F
authors: Himmel
authors: F
authors: F
authors: Bode
authors: H
authors: H
authors: Schunkert
authors: J
authors: J
authors: Weil
mesh_terms: D000959:Antihypertensive Agents / Q000627:therapeutic use; D017115:Catheter Ablation / Q000379:methods*; D004351:Drug Resistance; D004359:Drug Therapy, Combination; D004525:Efferent Pathways / Q000601:surgery; D006801:Humans; D006973:Hypertension / Q000601:surgery*; D007668:Kidney / Q000294:innervation*; D012077:Renal Artery / Q000294:innervation*; D013562:Sympathectomy / Q000379:methods*
chemical_list: D000959:Antihypertensive Agents