title: Clinical significance of anti-mitochondrial antibodies in a patient with chronic graft-versus-host disease following hematopoietic stem cell transplantation.
abstract: Recent studies indicate that patients with chronic graft-versus-host disease (GVHD) are not expected to show positivity for anti-mitochondrial antibody (AMA), which is a specific disease marker for primary biliary cirrhosis (PBC). A differential diagnosis between PBC and hepatic involvement of GVHD based on clinical manifestations and pathologic study is difficult because both diseases show similar results. Therefore, the presence of AMA may be important for distinguishing each disease. Here, we report a case of hepatic involvement of chronic GVHD with positive AMA, in which the pathologic findings and initial presentation of clinical findings were compatible with both PBC and chronic GVHD.
authors: Department of Internal Medicine, Dong-A University College of Medicine, Busan, Korea.
authors: Dong Hyun
authors: DH
authors: Lee
authors: Seok Jae
authors: SJ
authors: Huh
authors: Hyun Hwa
authors: HH
authors: Yoon
authors: Sung Woo
authors: SW
authors: Lee
authors: Kyeong Hee
authors: KH
authors: Kim
authors: Sung-Hyun
authors: SH
authors: Kim