title: Biologic response modifiers: relevance & repercussions.
abstract: Biologic response modifiers (BRMs) are substances that occur naturally in the body. They can also be manufactured in the laboratory and then administered as targeted therapy. Undoubtedly BRMs will find expanded role in terminal illness like cancer where other therapies have failed. However, great caution must be exercised in prescribing these agents in chronic indolent diseases where potential for ultimate harm might outweigh short-term benefits.
authors: Division of Endocrinology & Metabolism, Eastern Virginia Medical School, Norfolk, VA 23507, USA. rkhardori@gmail.com
authors: Romesh
authors: R
authors: Khardori
authors: Nancy
authors: N
authors: Misri Khardori
mesh_terms: D002908:Chronic Disease; D006706:Homeostasis / Q000502:physiology*; D006801:Humans; D007155:Immunologic Factors / Q000502:physiology / Q000627:therapeutic use*
chemical_list: D007155:Immunologic Factors