title: Undifferentiated carcinoma of the pancreas with osteoclast-like giant cells.
abstract: Undifferentiated carcinoma with osteoclast-like giant cells is a rare neoplasm of the exocrine pancreas. Some similar cases have been reported, but the histogenesis of these tumors varies and is controversial. We report here on a case of undifferentiated carcinoma of the pancreas with osteoclast-like giant cells. A 77-year old woman presented with abdominal pain and anorexia. Abdominal computed tomography and magnetic resonance imaging showed an approximately 10 × 5 cm highly attenuated mass arising from the tail of the pancreas and invading the spleen and adjacent bowel loop. The initial impression was a malignant endocrine tumor or solid-pseudopapillary tumor of the pancreas. The patient underwent a distal pancreatectomy with splenectomy and left hemicolectomy. The histopathology and immunohistochemistry helped make the diagnosis that of an undifferentiated carcinoma with osteoclast-like giant cells of the pancreas.
authors: Division of Hepatico Biliary Pancreatic Surgery, Department of Surgery, Chonnam National University Medical School, Gwangju, Korea.
authors: Young Hoe
authors: YH
authors: Hur
authors: Ho Hyun
authors: HH
authors: Kim
authors: Jin Shick
authors: JS
authors: Seoung
authors: Kyoung Won
authors: KW
authors: Seo
authors: Jin Woong
authors: JW
authors: Kim
authors: Yong Yeon
authors: YY
authors: Jeong
authors: Jae Hyuk
authors: JH
authors: Lee
authors: Yang Seok
authors: YS
authors: Koh
authors: Jung Chul
authors: JC
authors: Kim
authors: Hyun Jong
authors: HJ
authors: Kim
authors: Chol Kyoon
authors: CK
authors: Cho