title: [Contribution of mathematical modeling to vaccination decision making. Examples from varicella, rotavirus and papillomavirus vaccinations].
abstract: The decision to add a new vaccine to the immunization schedule is a complex and multidisciplinary process based on the risk-benefit balance and, increasingly, on the cost- effectiveness ratio. Such decisions now use mathematical models that can predict the indirect, and potentially detrimental, effects of mass vaccination on the epidemiology of the target disease. The adjunction of an economic component to the modeling process ensures that vaccination represents an efficient allocation of available financial resources in an increasingly constrained environment.
authors: Institut de Veille Sanitaire--94415 Saint-Maurice cedex. d.levybruhl@invs.sante.fr
authors: Daniel
authors: D
authors: Lévy-Bruhl
mesh_terms: D002644:Chickenpox / Q000517:prevention & control*; D003657:Decision Making / Q000502:physiology; D003661:Decision Support Techniques; D006801:Humans; D017589:Immunization Programs / Q000379:methods*; D008962:Models, Theoretical; D030361:Papillomavirus Infections / Q000517:prevention & control*; D053918:Papillomavirus Vaccines / Q000627:therapeutic use; D012400:Rotavirus Infections / Q000517:prevention & control*; D022243:Rotavirus Vaccines / Q000627:therapeutic use; D014611:Vaccination / Q000191:economics / Q000379:methods
chemical_list: D053918:Papillomavirus Vaccines; D022243:Rotavirus Vaccines