title: Decarboxylative benzylation and arylation of nitriles.
abstract: Decarboxylative benzylation of nitriles is achieved via coupling of metallated nitriles with Pd-π-benzyl complexes that are generated in situ from cyanoacetic benzyl esters. In addition, decarboxylative couplings of α,α-disubstituted 2-methylfuranyl cyanoacetates can lead to either decarboxylative arylation or benzylation depending on the reaction conditions.
authors: 2010 Malott Hall, 1251 Wescoe Hall Dr, Lawrence, KS, USA.
authors: Antonio
authors: A
authors: Recio
authors: Jeffrey D
authors: JD
authors: Heinzman
authors: Jon A
authors: JA
authors: Tunge
mesh_terms: D002384:Catalysis; D005663:Furans / Q000737:chemistry; D006841:Hydrocarbons, Aromatic / Q000737:chemistry*; D009570:Nitriles / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry
chemical_list: D005663:Furans; D006841:Hydrocarbons, Aromatic; D009570:Nitriles; D010165:Palladium