title: Presence of porcine parvovirus in sera from pigs is independent of antibody titers.
abstract: Porcine parvovirus (PPV) is a widespread DNA virus that causes reproductive failure in swine. The aim of the present study was to investigate the presence of PPV in sera of nursery piglets (healthy n = 191 and wasting n = 132) and regularly vaccinated sows (with different parity rank [PR] n = 129), collected from different herds. Altogether, 452 animals were sampled in 27 herds owned by five companies. All sera were analyzed for the presence of PPV DNA by nested-PCR. The samples from sows were in addition tested for the presence of antibodies by Hemagglutination Inhibition (HI). PPV DNA was detected in healthy piglets (15.7%), wasting piglets (18.2%) and sows (17.8%). 25 herds had at least one positive sample and four companies had positive animals. The serology revealed that 84.7% of the sows had detectable antibodies and the fourth PR sows had the highest mean PPV antibody titers. Thirteen sows (19.1%) were found to be positive for DNA detection in the presence of high levels of antibody titers (> 512). This finding indicates that PPV DNA can be detected in different swine production categories irrespective of antibody titers.
authors: Institute for Animal Hygiene and Veterinary Public Health, Faculty of Veterinary Medicine, University of Leipzig, Leipzig, Germany.
authors: André F
authors: AF
authors: Streck
authors: Danielle
authors: D
authors: Gava
authors: Carine K
authors: CK
authors: Souza
authors: Karla R
authors: KR
authors: Gonçalves
authors: Fernando P
authors: FP
authors: Bortolozzo
authors: Ivo
authors: I
authors: Wentz
authors: Cláudio W
authors: CW
authors: Canal
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000097:blood*; D004279:DNA, Viral / Q000097:blood*; D005260:Female; D008297:Male; D010298:Parity; D010322:Parvoviridae Infections / Q000097:blood / Q000276:immunology / Q000662:veterinary*; D028323:Parvovirus, Porcine / Q000235:genetics / Q000276:immunology / Q000302:isolation & purification*; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000097:blood / Q000662:veterinary* / Q000821:virology; D013552:Swine; D013553:Swine Diseases / Q000097:blood* / Q000276:immunology / Q000821:virology
chemical_list: D000914:Antibodies, Viral; D004279:DNA, Viral