title: Keratosis lichenoides chronica--case report.
abstract: Keratosis lichenoides chronica or Nekam's disease is a rare mucocutaneous dermatosis characterized by keratinization. It is chronic and progressive usually affecting individuals aged 20-40 years. Around 70 cases have been reported in the literature. Due to the rarity of this condition and the lack of effective treatment, it is a difficult disease to manage. In the case described below we present a 42-year old patient with violaceous and hyperkeratotic papules in linear, reticular or plaque form, located on the trunk and limbs for five years. Aphthous lesions in the oral cavity and shallow ulcers on the genitalia also formed part of the clinical manifestation. Pathologic examination was suggestive of keratosis lichenoides chronica. Acitretin and dapsone was introduced and the lesions partially improved.
authors: Serviço de Dermatologia, Complexo Hospitalar Universitário Edgard Santos, Universidade Federal da Bahia, Salvador, BA, Brasil. liviacibele@hotmail.com
authors: Livia Cibele Gomes
authors: LC
authors: Martins
authors: Marina
authors: M
authors: Horne
authors: Dário Nunes
authors: DN
authors: Moreira Júnior
authors: Ivonise
authors: I
authors: Follador
authors: Vitória Regina Pedreira de
authors: VR
authors: Almeida
mesh_terms: D017255:Acitretin / Q000627:therapeutic use; D000328:Adult; D000890:Anti-Infective Agents / Q000627:therapeutic use; D001706:Biopsy; D002908:Chronic Disease; D003622:Dapsone / Q000627:therapeutic use; D006801:Humans; D007641:Keratolytic Agents / Q000627:therapeutic use; D007642:Keratosis / Q000188:drug therapy / Q000473:pathology*; D017512:Lichenoid Eruptions / Q000188:drug therapy / Q000473:pathology*; D008297:Male; D012867:Skin / Q000473:pathology
chemical_list: D000890:Anti-Infective Agents; D007641:Keratolytic Agents; D003622:Dapsone; D017255:Acitretin