title: Nuclear actin and myosins: life without filaments.
abstract: Actin and myosin are major components of the cell cytoskeleton, with structural and regulatory functions that affect many essential cellular processes. Although they were traditionally thought to function only in the cytoplasm, it is now well accepted that actin and multiple myosins are found in the nucleus. Increasing evidence on their functional roles has highlighted the importance of these proteins in the nuclear compartment.
authors: Department of Physiology and Biophysics, University of Illinois at Chicago, Chicago, Illinois 60612, USA. primal@uic.edu
authors: Primal
authors: P
authors: de Lanerolle
authors: Leonid
authors: L
authors: Serebryannyy
mesh_terms: D000199:Actins / Q000737:chemistry / Q000378:metabolism*; D000818:Animals; D002467:Cell Nucleus / Q000378:metabolism*; D003593:Cytoplasm / Q000378:metabolism; D006801:Humans; D009218:Myosins / Q000737:chemistry / Q000378:metabolism*; D009687:Nuclear Proteins / Q000378:metabolism*; D011487:Protein Conformation; D015398:Signal Transduction; D013329:Structure-Activity Relationship
chemical_list: D000199:Actins; D009687:Nuclear Proteins; D009218:Myosins