title: [Von Willebrand disease type 1 and pregnancy].
abstract: The von Willebrand-Jürgens syndrome (VWJS) type 1 is a common hereditary bleeding disorder with a bleeding tendency located especially in the mucous membranes. Women suffering from VWJS type 1 show menorrhagia and prolonged postoperative bleedings. During pregnancy the clinical presentation varies by the increase of the von Willebrand factors.  In this article the laboratory findings and the clinical presentation of patients with VWJS during pregnancy was examined. The necessity of interventions during pregnancy and at the time of delivery was under consideration.
authors: Zentrum für Blutgerinnungsstörungen, MVZ Labor Dr. Reising-Ackermann und Kollegen, Strümpellstraße 40, Leipzig. u.scholz@labor-leipzig.de
authors: U
authors: U
authors: Scholz
authors: J
authors: J
authors: Oppermann
authors: A
authors: A
authors: Siegemund
authors: R
authors: R
authors: Schobess
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008595:Menorrhagia / Q000097:blood* / Q000150:complications / Q000175:diagnosis*; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000097:blood* / Q000175:diagnosis*; D056725:von Willebrand Disease, Type 1 / Q000097:blood* / Q000150:complications / Q000175:diagnosis*