title: Rapid microparticle patterning by enhanced dielectrophoresis effect on a double-layer electrode substrate.
abstract: We present a feasible dielectrophoresis (DEP) approach for rapid patterning of microparticles on a reusable double-layer electrode substrate in microfluidics. Simulation analysis demonstrated that the DEP force was dramatically enhanced by the induced electric field on top interdigitated electrodes. By adjusting electric field intensity through the bottom electrodes on thin glass substrate (100 μm), polystyrene particles (10 μm) were effectively patterned by top electrodes within several seconds (<5 s). The particle average velocity can reach a maximum value of about 20.0±3.0 μm/s at 1 MHz with the strongest DEP force of 1.68 pN. This approach implements integration of functional electrodes into one substrate and avoids direct electrical connection to biological objects, providing a potential lab-on-chip system for biological applications.
authors: Department of Physics, Key Laboratory of Acoustic and Photonic Materials and Devices of Ministry of Education, Wuhan University, Hubei, P R China.
authors: Wei
authors: W
authors: Cheng
authors: Si-Zhe
authors: SZ
authors: Li
authors: Qian
authors: Q
authors: Zeng
authors: Xiao-Lei
authors: XL
authors: Yu
authors: Yu
authors: Y
authors: Wang
authors: Helen Lai Wah
authors: HL
authors: Chan
authors: Wei
authors: W
authors: Liu
authors: Shi-Shang
authors: SS
authors: Guo
authors: Xing-Zhong
authors: XZ
authors: Zhao
mesh_terms: D004566:Electrodes; D004586:Electrophoresis / Q000295:instrumentation / Q000379:methods*; D004867:Equipment Design; D005898:Glass; D006367:HeLa Cells; D006801:Humans; D046210:Microfluidic Analytical Techniques / Q000295:instrumentation* / Q000379:methods*; D008863:Microspheres; D010316:Particle Size; D011137:Polystyrenes / Q000737:chemistry; D046888:Tissue Array Analysis / Q000295:instrumentation
chemical_list: D011137:Polystyrenes