title: Neurophysiological investigation of idiopathic acquired auditory-visual synesthesia.
abstract: We present a case of acquired auditory-visual synesthesia and its neurophysiological investigation in a healthy 42-year-old woman. She started experiencing persistent positive and intermittent negative visual phenomena at age 37 followed by auditory-visual synesthesia. Her neurophysiological investigation included video-EEG, fMRI, and MEG. Auditory stimuli (700 Hz, 50 ms duration, 0.5 s ISI) were presented binaurally at 60 db above the hearing threshold in a dark room. The patient had bilateral symmetrical auditory-evoked neuromagnetic responses followed by an occipital-evoked field 16.3 ms later. The activation of occipital cortex following auditory stimuli may represent recruitment of existing cross-modal sensory pathways.
authors: Department of Neurology, School of Medicine, University of Utah, Salt Lake City, UT 84132, USA. pegah.afra@hsc.utah.edu
authors: Pegah
authors: P
authors: Afra
authors: Jeffrey
authors: J
authors: Anderson
authors: Michael
authors: M
authors: Funke
authors: Michael
authors: M
authors: Johnson
authors: Fumisuke
authors: F
authors: Matsuo
authors: Tawnya
authors: T
authors: Constantino
authors: Judith
authors: J
authors: Warner
mesh_terms: D000161:Acoustic Stimulation; D000328:Adult; D004569:Electroencephalography; D005072:Evoked Potentials, Auditory; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D015225:Magnetoencephalography; D008297:Male; D009778:Occipital Lobe / Q000503:physiopathology; D010468:Perceptual Disorders / Q000473:pathology / Q000503:physiopathology* / Q000523:psychology*; D010775:Photic Stimulation; D000080311:Synesthesia