title: Evaluation of fetal lungs and stomach in the determination of amniotic sac infection.
abstract: This study evaluated neutrophils in fetal lung/stomach, in association with chorioamnionitis. Reports/slides from fetuses 13-24 weeks with a confirmed histologic diagnosis of placental chorioamnionitis were reviewed. There were 94 cases with no neutrophils in the lungs or stomach, and 106 with neutrophils in lungs, stomach, or both (53%). Thirteen percent showed neutrophils in the lungs only. Fetuses with no neutrophils were older than those with neutrophils in the stomach only (p = 0.008). Neutrophils in fetal lungs/stomach are common, and may confirm chorioamnionitis when the placenta is not available. Submission of gastric sections increases identification of chorioamnionitis.
authors: Department of Pathology, UMDNJ-New Jersey Medical School, Newark, New Jersey 07101, USA. hellerds@umdnj.edu
authors: Debra S
authors: DS
authors: Heller
mesh_terms: D002821:Chorioamnionitis / Q000175:diagnosis / Q000473:pathology*; D005260:Female; D005333:Fetus / Q000473:pathology*; D005865:Gestational Age; D006801:Humans; D008168:Lung / Q000473:pathology*; D008297:Male; D009504:Neutrophils / Q000473:pathology; D011247:Pregnancy; D012189:Retrospective Studies; D013270:Stomach / Q000473:pathology*