title: Severe cutaneous reaction to photodynamic therapy with blue light.
abstract: Photodynamic therapy (PDT) has been considered a safe and efficacious treatment for actinic keratoses (AKs) of the scalp and face. The procedure involves exposing a patient to a blue light source 1-4 hours after application of photosensitizing aminolevulinic acid (ALA) at a dose of 10 J/cm2 for up to 1000 seconds.(1,2) We suggest that amount of exposure time and area of exposure should be stratified according to baseline photodamage.
authors: Department of Dermatology, Texas Tech University Health Sciences Center, Lubbock, TX, USA.
authors: Mary M
authors: MM
authors: Moore
authors: Cindy
authors: C
authors: Reyna
authors: Richard H
authors: RH
authors: Hope
mesh_terms: D000622:Aminolevulinic Acid / Q000008:administration & dosage / Q000009:adverse effects; D005500:Follow-Up Studies; D006801:Humans; D055623:Keratosis, Actinic / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D010778:Photochemotherapy / Q000009:adverse effects* / Q000379:methods; D017319:Photosensitizing Agents / Q000008:administration & dosage / Q000009:adverse effects; D012720:Severity of Illness Index; D012871:Skin Diseases / Q000209:etiology* / Q000473:pathology; D013997:Time Factors
chemical_list: D017319:Photosensitizing Agents; D000622:Aminolevulinic Acid