title: Cyclization of 5-hexynoic acid to 3-alkoxy-2-cyclohexenones.
abstract: The one-pot cyclization of 5-hexynoic acid to produce 3-alkoxy-2-cyclohexenones proceeds in good yields (58-90%). 3-Hexynoic acid was converted to its acyl chloride with the aid of oxalyl chloride and was cyclized to 3-chloro-2-cyclohexenone upon addition of indium(III) chloride. Subsequent addition of alcohol nucleophiles led to the desired 3-alkoxy-2-cyclohexenones.
authors: Department of Chemistry, College of St. Benedict, St. John's University, St. Joseph, MN 56374, USA.
authors: Anne T
authors: AT
authors: Hylden
authors: Eric J
authors: EJ
authors: Uzelac
authors: Zeljko
authors: Z
authors: Ostojic
authors: Ting-Ting
authors: TT
authors: Wu
authors: Keely L
authors: KL
authors: Sacry
authors: Krista L
authors: KL
authors: Sacry
authors: Lin
authors: L
authors: Xi
authors: T Nicholas
authors: TN
authors: Jones