title: Esophageal preservation in esophageal high-grade dysplasia and intramucosal adenocarcinoma.
abstract: The management of esophageal high-grade dysplasia (HGD) and intramucosal adenocarcinoma remains controversial. Because lymph node involvement is unlikely in this setting, interest in the treatment strategies for esophageal preservation has grown. Esophageal preservation indicates any endoluminal procedure that is used in an attempt to completely eradicate disease while preserving the anatomic structure of the esophagus. The goal of esophagus-preserving approaches is to provide definitive therapy while avoiding the morbidity of esophagectomy. This article describes the patient selection and the status of currently available esophagus-preserving options, and discusses the strategy for treating HGD and intramusocal adenocarcinoma.
authors: Division of Thoracic and Foregut Surgery, Department of Cardiothoracic Surgery, University of Pittsburgh Medical Center, 5200 Centre Avenue, Suite 715, Pittsburgh, PA 15232, USA. hoppot2@upmc.edu
authors: Toshitaka
authors: T
authors: Hoppo
authors: Shah D
authors: SD
authors: Rachit
authors: Blair A
authors: BA
authors: Jobe
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D001471:Barrett Esophagus / Q000473:pathology / Q000601:surgery; D004938:Esophageal Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D004945:Esophagoscopy; D004947:Esophagus / Q000601:surgery*; D006801:Humans; D009364:Neoplasm Recurrence, Local; D011230:Precancerous Conditions / Q000175:diagnosis / Q000473:pathology / Q000601:surgery