title: Validation of a home environment test battery for supporting assessments in advanced Parkinson's disease.
abstract: Test sequences in a test battery for Parkinson's disease patients, consisting of self-assessments and motor tests, were carried out repeatedly in a telemedicine setting, during week-long test periods and results were summarized in an 'overall score'. 35 patients in stable and fluctuating conditions (15 age- and gender-matched pairs) used the test battery for 1 week, and were then assessed with UPDRS and PDQ-39. This procedure was repeated 1 week later, without treatment changes. Reliability was assessed by intraclass correlation coefficients and Cronbach's alpha. Convergent validity was assessed by Spearman rank correlations and known-groups' validity, by the Mann-Whitney test. According to anonymous usability questionnaires, the patients could easily complete the tasks. Median compliance (93%) and test-retest reliability (0.88) were good. The correlations between overall score and total UPDRS (-0.64) and PDQ-39 (-0.72) were adequate. Median overall score was 18% better in the stable compared to the fluctuating group (p = 0.0014).
authors: Academy of Industry and Society, Computer Science, Dalarna University, 781 88 Borlänge, Sweden. jwe@du.se
authors: Jerker
authors: J
authors: Westin
authors: Mauro
authors: M
authors: Schiavella
authors: Mevludin
authors: M
authors: Memedi
authors: Dag
authors: D
authors: Nyholm
authors: Mark
authors: M
authors: Dougherty
authors: Angelo
authors: A
authors: Antonini
mesh_terms: D000203:Activities of Daily Living; D000368:Aged; D016022:Case-Control Studies; D034201:Computers, Handheld; D005260:Female; D006305:Health Status Indicators; D006801:Humans; D007558:Italy; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000175:diagnosis* / Q000503:physiopathology*; D011788:Quality of Life; D015203:Reproducibility of Results; D012647:Self-Assessment; D018709:Statistics, Nonparametric; D011795:Surveys and Questionnaires