title: Dopamine: the forgotten felon in type 2 diabetes.
abstract: This paper reviews recent patents and development related to bromocriptine and other dopaminergic agents, being used or suggested for use in the management of diabetes. The article discusses the contribution of dopaminergic pathways to glucose, energy and weight homeostasis. The mechanism of action of bromocriptine, its pharmacological properties, efficacy, safety and tolerability are assessed. The article also covers recent patents which may be utilized to improve the efficiency and tolerability of dopamine-based therapy in diabetes mellitus.
authors.affiliation: Bharti Hospital, Kunjpura Road, Karnal, 132001, Haryana, India. brideknl@gmail.com
authors.forename: Sanjay
authors.initials: S
authors.lastname: Kalra
authors.forename: Bharti
authors.initials: B
authors.lastname: Kalra
authors.forename: Navneet
authors.initials: N
authors.lastname: Agrawal
authors.forename: Satish
authors.initials: S
authors.lastname: Kumar
mesh_terms: D000818:Animals; D001835:Body Weight / Q000187:drug effects / Q000502:physiology; D001971:Bromocriptine / Q000009:adverse effects / Q000494:pharmacology / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D003924:Diabetes Mellitus, Type 2 / Q000188:drug therapy* / Q000378:metabolism / Q000503:physiopathology; D018491:Dopamine Agonists / Q000009:adverse effects / Q000494:pharmacology / Q000627:therapeutic use*; D059290:Dopaminergic Neurons / Q000187:drug effects / Q000502:physiology*; D004347:Drug Interactions; D004734:Energy Metabolism / Q000187:drug effects / Q000502:physiology; D005947:Glucose / Q000378:metabolism; D006801:Humans; D010330:Patents as Topic
chemical_list: D018491:Dopamine Agonists; D001971:Bromocriptine; D005947:Glucose