title: Sinonasal inverted papilloma associated with malignancy: the role of human papillomavirus infection and its implications for radiotherapy.
abstract: Sinonasal inverted papilloma (IP) is a benign but destructive tumor originating from the ciliated respiratory mucosa of the sinonasal tract. It can be associated with malignancy (squamous cell histology, in particular) and human papillomavirus infection has been investigated as a potential etiological factor linked to malignant alterations of IP. Surgery is the treatment of choice for IP, however, radiotherapy as an adjunct to surgery is indicated for IP with associated malignancy.
authors.affiliation: Department of Radiation Oncology, Institute of Oncology, Ljubljana, Slovenia.
authors.forename: Primož
authors.initials: P
authors.lastname: Strojan
authors.forename: Alfio
authors.initials: A
authors.lastname: Ferlito
authors.forename: Valerie J
authors.initials: VJ
authors.lastname: Lund
authors.forename: David W
authors.initials: DW
authors.lastname: Kennedy
authors.forename: Carl E
authors.initials: CE
authors.lastname: Silver
authors.forename: Alessandra
authors.initials: A
authors.lastname: Rinaldo
authors.forename: Leon
authors.initials: L
authors.lastname: Barnes
mesh_terms: D005260:Female; D006801:Humans; D008297:Male; D009296:Nasal Cavity; D018308:Papilloma, Inverted / Q000150:complications / Q000532:radiotherapy*; D030361:Papillomavirus Infections / Q000150:complications; D010255:Paranasal Sinus Neoplasms / Q000150:complications / Q000532:radiotherapy*