title: Simple rapid near-patient diagnostics for tuberculosis remain elusive--is a "treat-to-test" strategy more realistic?
authors.affiliation: KIT Biomedical Research, Royal Tropical Institute, Amsterdam, The Netherlands. a.d.hertog@kit.nl
authors.forename: Alice L
authors.initials: AL
authors.lastname: den Hertog
authors.forename: Oleg A
authors.initials: OA
authors.lastname: Mayboroda
authors.forename: Paul R
authors.initials: PR
authors.lastname: Klatser
authors.forename: Richard M
authors.initials: RM
authors.lastname: Anthony
mesh_terms: D000907:Antibodies, Bacterial / Q000097:blood; D000942:Antigens, Bacterial / Q000032:analysis; D000995:Antitubercular Agents / Q000627:therapeutic use*; D015415:Biomarkers / Q000032:analysis*; D006801:Humans; D007159:Immunologic Tests; D009169:Mycobacterium tuberculosis / Q000276:immunology / Q000472:pathogenicity; D012680:Sensitivity and Specificity; D014376:Tuberculosis / Q000175:diagnosis* / Q000188:drug therapy*
chemical_list: D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial; D000995:Antitubercular Agents; D015415:Biomarkers
references.citation: N Engl J Med. 2010 Sep 9;363(11):1005-15
references.pmid: 20825313
references.citation: Int J Tuberc Lung Dis. 2004 Dec;8(12):1396-400
references.pmid: 15636484
references.citation: Am J Respir Crit Care Med. 2003 May 15;167(10):1348-54
references.pmid: 12519740
references.citation: J Pak Med Assoc. 2004 Feb;54(2):88-95
references.pmid: 15134210
references.citation: Int J Tuberc Lung Dis. 2011 Mar;15(3):287-95
references.pmid: 21333094
references.citation: PLoS One. 2010 Nov 11;5(11):e13938
references.pmid: 21085642
references.citation: J Clin Microbiol. 2010 Dec;48(12):4512-8
references.pmid: 20962138
references.citation: Proteomics. 2010 Sep;10(17):3190-202
references.pmid: 20662102
references.citation: Ann Acad Med Singap. 2002 Jan;31(1):92-6
references.pmid: 11885505
references.citation: Respiration. 2005 Jul-Aug;72(4):369-74
references.pmid: 16088279
references.citation: J Trop Med. 2009;2009:398767
references.pmid: 20309419
references.citation: Thorax. 2004 Aug;59(8):704-7
references.pmid: 15282393
references.citation: Int Immunol. 2010 Sep;22(9):775-82
references.pmid: 20624776
references.citation: Nat Rev Microbiol. 2011 Mar;9(3):204-13
references.pmid: 21326275
references.citation: Nature. 2010 Aug 19;466(7309):973-7
references.pmid: 20725040
references.citation: Clin Infect Dis. 2002 Jun 15;34(12):1607-12
references.pmid: 12032896
references.citation: PLoS One. 2010 Mar 24;5(3):e9848
references.pmid: 20352098
references.citation: Eur J Clin Microbiol Infect Dis. 2002 Nov;21(11):803-9
references.pmid: 12461590
references.citation: Int J Tuberc Lung Dis. 2009 Jan;13(1):79-83
references.pmid: 19105883
references.citation: Proc Natl Acad Sci U S A. 2010 Aug 17;107(33):14703-8
references.pmid: 20668240
references.citation: J Clin Microbiol. 2010 Jul;48(7):2495-501
references.pmid: 20504986
references.citation: PLoS Med. 2007 Jun;4(6):e202
references.pmid: 17564490