title: [Hodgkin's disease and breast cancer: for which patients is there an association? A series from Institut Bergonié].
abstract: OBJECTIVE
  Breast cancer is the most frequent secondary tumor for women treated for Hodgkin's disease. It is important to study the risk factors associated to be able to adapt the monitoring of these women.
  
  
  METHODS
  This is a retrospective study from Institut Bergonié, a comprehensive French Cancer Center, concerning the women treated for Hodgkin's disease and having developed a breast cancer.
  
  
  RESULTS
  Among 328 women treated for Hodgkin's disease between January 1968 and December 1994, 20 patients developed 25 breast cancers. The average age of the patients during the irradiation was 24 years and the average period of occurrence of the cancer was 19 years. An irradiation of the chest wall and an under-diaphragmatic irradiation in doses of 40Gy are risk factors for the occurrence of breast cancer. A young age, less than 30, in the treatment of Hodgkin's disease tend to be significant.
  
  
  CONCLUSIONS
  This population of women with a high risk of breast cancer thus has to benefit from an appropriate monitoring program, which is what we suggest setting up in the Institut Bergonié.
authors.affiliation: Département de chirurgie, institut Bergonié, université Bordeaux Ségalen, 229 cours de l'Argonne, Bordeaux cedex, France.
authors.forename: V
authors.initials: V
authors.lastname: Brillaud
authors.forename: C
authors.initials: C
authors.lastname: Tunon de Lara
authors.forename: P
authors.initials: P
authors.lastname: Richaud
authors.forename: C
authors.initials: C
authors.lastname: Breton-Callu
authors.forename: V
authors.initials: V
authors.lastname: Brouste
authors.forename: E
authors.initials: E
authors.lastname: Bussières
mesh_terms: D000328:Adult; D000367:Age Factors; D001943:Breast Neoplasms / Q000209:etiology* / Q000473:pathology; D005260:Female; D005602:France; D006689:Hodgkin Disease / Q000532:radiotherapy*; D006801:Humans; D008875:Middle Aged; D009381:Neoplasms, Radiation-Induced / Q000209:etiology*; D012189:Retrospective Studies; D012307:Risk Factors; D055815:Young Adult