title: Superiority of measuring apolipoprotein B to conventional lipid profile predicting risk of acute coronary syndrome in young people.
abstract: The purpose of this study is to compare the importance and its superiority of apolipoprotein B (apoB) over conventional lipid profile for predicting risk of acute coronary syndrome in young people of Bangladesh. This case-control study was carried out in Department of Cardiology, of Mymensingh Medical College Hospital within the period from June 2009 to May 2010. A total 50 case of 18-45 years of age with first attack of acute coronary syndrome admitted in coronary care unit and 50 healthy controls of same age and sex distribution were studied. Twenty five (50.0%) of the studied case had hyper apoB condition, those low density lipoprotein cholesterol (LDL-C) level was normal, thus conventional lipid profile underestimated the risk. Among the controls 23(46.0%) with high LDL-C had hyper apoB condition. Hyper-ApoB in these controls may cause acute coronary syndrome in future. The present study shows significant association of apolipoprotein B as an independent determinant and estimation of apoB other than conventional lipid profile may be an alternative tool for predicting risk of development of acute coronary syndrome in young people.
authors.affiliation: Mymensingh Medical College Hospital, Mymensingh, Bangladesh. ganapati. aditya@yahoo.com
authors.forename: G P
authors.initials: GP
authors.lastname: Aditya
authors.forename: M A
authors.initials: MA
authors.lastname: Bari
authors.forename: M S
authors.initials: MS
authors.lastname: Bari
mesh_terms: D054058:Acute Coronary Syndrome / Q000097:blood / Q000209:etiology*; D000293:Adolescent; D000328:Adult; D001055:Apolipoproteins B / Q000097:blood*; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D008055:Lipids / Q000097:blood*; D008297:Male; D012306:Risk; D055815:Young Adult
chemical_list: D001055:Apolipoproteins B; D008055:Lipids