title: Involvement of methicillin-susceptible Staphylococcus aureus related to sequence type 25 and harboring pvl genes in a case of carotid cavernous fistula after community-associated sepsis.
abstract: Staphylococcus aureus encoding Panton-Valentine leukocidin (PVL) genes has become the cause of life-threatening infections. We describe a case of carotid cavernous fistula after bacteremia in a 12-year-old male, caused by a methicillin-susceptible S. aureus isolate carrying the pvl, fnbA, and ebpS genes and related to sequence type 25 (ST25). The patient's condition was complicated by pleural empyema and osteomyelitis in the right femur. The patient was discharged in good clinical condition after 160 days of hospitalization.
authors.affiliation: Hospital Pedro Ernesto, State University of Rio de Janeiro,a and Instituto de Microbiologia Paulo de Góes, Federal University of Rio de Janeiro,b Rio de Janeiro, Brazil.
authors.forename: Paulo V
authors.initials: PV
authors.lastname: Damasco
authors.forename: Raiane C
authors.initials: RC
authors.lastname: Chamon
authors.forename: Angélica T L
authors.initials: AT
authors.lastname: Barbosa
authors.forename: Sérgio
authors.initials: S
authors.lastname: da Cunha
authors.forename: José H W
authors.initials: JH
authors.lastname: Aquino
authors.forename: Fernanda S
authors.initials: FS
authors.lastname: Cavalcante
authors.forename: Kátia R N
authors.initials: KR
authors.lastname: Dos Santos
mesh_terms: D000792:Angiography; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001427:Bacterial Toxins / Q000235:genetics*; D020216:Carotid-Cavernous Sinus Fistula / Q000150:complications / Q000175:diagnosis* / Q000382:microbiology / Q000473:pathology; D002648:Child; D017714:Community-Acquired Infections / Q000150:complications / Q000382:microbiology*; D004653:Empyema / Q000175:diagnosis / Q000382:microbiology; D005098:Exotoxins / Q000235:genetics*; D005838:Genotype; D006801:Humans; D007956:Leukocidins / Q000235:genetics*; D008297:Male; D008712:Methicillin / Q000494:pharmacology; D058889:Molecular Typing; D010019:Osteomyelitis / Q000175:diagnosis / Q000453:epidemiology; D018805:Sepsis / Q000150:complications / Q000382:microbiology*; D013203:Staphylococcal Infections / Q000382:microbiology*; D013211:Staphylococcus aureus / Q000145:classification / Q000187:drug effects / Q000235:genetics / Q000302:isolation & purification*; D037521:Virulence Factors / Q000235:genetics
chemical_list: D000900:Anti-Bacterial Agents; D001427:Bacterial Toxins; D005098:Exotoxins; D007956:Leukocidins; C078284:Panton-Valentine leukocidin; D037521:Virulence Factors; D008712:Methicillin
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