title: Verification and implementation of a modified split Hopkinson pressure bar technique for characterizing biological tissue and soft biosimulant materials under dynamic shear loading.
abstract: Modeling human body response to dynamic loading events and developing biofidelic human surrogate systems require accurate material properties over a range of loading rates for various human organ tissues. This work describes a technique for measuring the shear properties of soft biomaterials at high rates of strain (100-1000 s(-1)) using a modified split Hopkinson pressure bar (SHPB). Establishing a uniform state of stress in the sample is a fundamental requirement for this type of high-rate testing. Input pulse shaping was utilized to tailor and control the ramping of the incident loading pulse such that a uniform stress state could be maintained within the specimen from the start of the test. Direct experimental verification of the stress uniformity in the sample was obtained via comparison of the force measured by piezoelectric quartz force gages on both the input and the output sides of the shear specimen. The technique was demonstrated for shear loading of silicone gel biosimulant materials and porcine brain tissue. Finite element simulations were utilized to further investigate the effect of pulse shaping on the loading rate and rise time. Simulations also provided a means for visualization of the degree of shear stress and strain uniformity in the specimen during an experiment. The presented technique can be applied to verify stress uniformity and ensure high quality data when measuring the dynamic shear modulus of soft biological simulants and tissue.
authors.affiliation: The Johns Hopkins University, Applied Physics Laboratory, 11100 Johns Hopkins Rd, Laurel, MD 20723, United States.
authors.forename: M M
authors.initials: MM
authors.lastname: Trexler
authors.forename: A M
authors.initials: AM
authors.lastname: Lennon
authors.forename: A C
authors.initials: AC
authors.lastname: Wickwire
authors.forename: T P
authors.initials: TP
authors.lastname: Harrigan
authors.forename: Q T
authors.initials: QT
authors.lastname: Luong
authors.forename: J L
authors.initials: JL
authors.lastname: Graham
authors.forename: A J
authors.initials: AJ
authors.lastname: Maisano
authors.forename: J C
authors.initials: JC
authors.lastname: Roberts
authors.forename: A C
authors.initials: AC
authors.lastname: Merkle
mesh_terms: D000818:Animals; D040761:Biomimetic Materials; D001921:Brain / Q000166:cytology; D020342:Finite Element Analysis; D008422:Materials Testing / Q000295:instrumentation*; D011312:Pressure; D033081:Shear Strength; D013314:Stress, Mechanical