title: Giant mediastinal parathyroid adenoma.
abstract: Primary hyperparathyroidism is most commonly caused by either a parathyroid adenoma or parathyroid hyperplasia. Parathyroid adenomas also rarely attain huge proportions. We present a case of a 63-year-old female patient causing hypercalcemia and the mass which is located in the mediastinum. High intact parathormone level secondary to an ectopic hypersecretory parathyroid adenoma were detected (642 pg/mL). It was removed via a right thoracic approach. In this case parathyroid adenoma measuring 7 x 5 x 4 cm and weighing 145 g; to our knowledge the greatest mass reported in the literature. Despite its huge size it did not cause many of the hypercalcemic symptoms.
authors.affiliation: Clinic of Chest Surgery, Ankara Training and Research Hospital, Ankara, Turkey.
authors.forename: Hüseyin
authors.initials: H
authors.lastname: Cakmak
authors.forename: Arif Osman
authors.initials: AO
authors.lastname: Tokat
authors.forename: Sezgin
authors.initials: S
authors.lastname: Karasu
authors.forename: Murat
authors.initials: M
authors.lastname: Özkan
mesh_terms: D000236:Adenoma / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D005260:Female; D006801:Humans; D006934:Hypercalcemia / Q000175:diagnosis / Q000209:etiology; D006961:Hyperparathyroidism / Q000175:diagnosis / Q000209:etiology; D008482:Mediastinum / Q000473:pathology* / Q000601:surgery; D008875:Middle Aged; D010282:Parathyroid Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D016105:Parathyroidectomy / Q000379:methods; D016896:Treatment Outcome