title: Synthetic augmentation for massive rotator cuff tears.
abstract: The management of massive, irreparable rotator cuff tears is challenging. They are associated with persistent defects, weakness, and poor outcomes, and can cause an uncoupling of forces across the glenohumeral joint, with unstable shoulder kinematics. There has been much interest in the development of scaffolds to bridge massive rotator cuff tears. As allograft materials may produce inflammatory responses in the host, there is notable interest in developing synthetic grafts for surgical use. Benefits and limitations of the available synthetic scaffolds for augmentation of rotator cuff tears are reported in the present review.
authors.affiliation: Department of Orthopaedic and Trauma Surgery, Campus Bio-Medico University, Via Alvaro del Portillo, Trigoria Rome, Italy.
authors.forename: Umile Giuseppe
authors.initials: UG
authors.lastname: Longo
authors.forename: Alfredo
authors.initials: A
authors.lastname: Lamberti
authors.forename: Wasim S
authors.initials: WS
authors.lastname: Khan
authors.forename: Nicola
authors.initials: N
authors.lastname: Maffulli
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Denaro
mesh_terms: D000818:Animals; D001696:Biomechanical Phenomena; D004285:Dogs; D006041:Goats; D006801:Humans; D007593:Joint Instability / Q000503:physiopathology / Q000601:surgery; D011817:Rabbits; D051381:Rats; D017006:Rotator Cuff / Q000503:physiopathology; D000070636:Rotator Cuff Injuries; D012720:Severity of Illness Index; D012756:Sheep; D012782:Shoulder / Q000503:physiopathology / Q000601:surgery; D013708:Tendon Injuries / Q000503:physiopathology / Q000601:surgery*; D054457:Tissue Scaffolds; D016896:Treatment Outcome