title: Rhabdomyolysis, acute kidney injury and transverse myelitis due to naive heroin exposure.
abstract: Heroin exposure can cause various complications like seizures, stroke, spongiform encephalopathy, transverse myelopathy, plexopathy, compartment syndrome, rhabdomyolysis and renal failure due to various mechanisms. We report here a young male who smoked heroin for the first time and developed transverse myelitis, rhabdomyolysis and acute kidney injury requiring dialysis. His renal recovery was complete by four weeks, while neurological improvement occurred 8 to 12 weeks later. This case suggests a common pathogenic mechanism of heroin intoxication involving multiple systems of the body.
authors.affiliation: Department of Nephrology, All India Institute of Medical Sciences, New Delhi, India. parthankur@yahoo.com
authors.forename: Ankur
authors.initials: A
authors.lastname: Gupta
authors.forename: Ambar
authors.initials: A
authors.lastname: Khaira
authors.forename: Suman
authors.initials: S
authors.lastname: Lata
authors.forename: Sanjay Kumar
authors.initials: SK
authors.lastname: Agarwal
authors.forename: Suresh C
authors.initials: SC
authors.lastname: Tiwari
mesh_terms: D058186:Acute Kidney Injury / Q000139:chemically induced*; D000328:Adult; D003932:Heroin / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D001239:Inhalation; D008279:Magnetic Resonance Imaging; D008297:Male; D009188:Myelitis, Transverse / Q000139:chemically induced* / Q000175:diagnosis; D009294:Narcotics / Q000008:administration & dosage / Q000009:adverse effects*; D012206:Rhabdomyolysis / Q000139:chemically induced*
chemical_list: D009294:Narcotics; D003932:Heroin