title: Using cluster heat maps to investigate relationships between body composition and laboratory measurements in HIV-infected and HIV-uninfected children and young adults.
abstract: Cluster heat maps were used to investigate relationships between body composition, lipid levels, and glucose metabolism in HIV-infected and HIV-uninfected children and young adults using data from a cross-sectional study. Three distinct clusters of participants were identified. One group had lower body fat and higher lipid measures and was mostly HIV infected. The other 2 groups were a mix of HIV-infected and HIV-uninfected participants. Of these, 1 cluster had more participants with higher body fat and insulin resistance, which are risk factors for future cardiovascular disease, and the other had relatively normal measurements on all outcomes.
authors.affiliation: Center for Biostatistics in AIDS Research, Harvard School of Public Health, Boston, MA, USA. lindsey@sdac.harvard.edu
authors.forename: Jane C
authors.initials: JC
authors.lastname: Lindsey
authors.forename: Denise L
authors.initials: DL
authors.lastname: Jacobson
authors.forename: Hong
authors.initials: H
authors.lastname: Li
authors.forename: E Andres
authors.initials: EA
authors.lastname: Houseman
authors.forename: Grace M
authors.initials: GM
authors.lastname: Aldrovandi
authors.forename: Kathleen
authors.initials: K
authors.lastname: Mulligan
mesh_terms: D015502:Absorptiometry, Photon; D000293:Adolescent; D001786:Blood Glucose / Q000378:metabolism*; D001823:Body Composition / Q000502:physiology*; D002648:Child; D016000:Cluster Analysis; D003430:Cross-Sectional Studies; D005260:Female; D006678:HIV / Q000302:isolation & purification*; D015658:HIV Infections / Q000378:metabolism*; D006801:Humans; D050356:Lipid Metabolism / Q000502:physiology*; D016015:Logistic Models; D008297:Male; D055815:Young Adult
chemical_list: D001786:Blood Glucose
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