title: Scedosporium apiospermum atrial mycetomas after lung transplantation for cystic fibrosis.
abstract: A 37-year-old patient with cystic fibrosis underwent double lung transplantation. She developed disseminated Scedosporium apiospermum infection 2 months after surgery. Along with multiple brain abscesses, lung infection, and chorioretinitis, a cardiac echo revealed 2 large intra-atrial mycetomas floating close to the right upper pulmonary vein orifice. The mycetomas were removed through a trans-atrial approach under cardiopulmonary by pass; histology and cultures confirmed the diagnosis. Despite intensive treatment, the patient succumbed from massive brain hemorrhage on the 10th postoperative day.
authors.affiliation: Department of Cardiac Surgery, University of Rome Sapienza, Rome, Italy. federico.venuta@uniroma1.it
authors.forename: F
authors.initials: F
authors.lastname: Miraldi
authors.forename: M
authors.initials: M
authors.lastname: Anile
authors.forename: F
authors.initials: F
authors.lastname: Ruberto
authors.forename: L
authors.initials: L
authors.lastname: Tritapepe
authors.forename: F
authors.initials: F
authors.lastname: Puglese
authors.forename: S
authors.initials: S
authors.lastname: Quattrucci
authors.forename: T
authors.initials: T
authors.lastname: Messina
authors.forename: D
authors.initials: D
authors.lastname: Vitolo
authors.forename: F
authors.initials: F
authors.lastname: Venuta
mesh_terms: D000328:Adult; D000935:Antifungal Agents / Q000008:administration & dosage / Q000627:therapeutic use; D003550:Cystic Fibrosis / Q000628:therapy*; D017809:Fatal Outcome; D005260:Female; D006325:Heart Atria / Q000473:pathology*; D006801:Humans; D016040:Lung Transplantation / Q000009:adverse effects*; D008271:Mycetoma / Q000382:microbiology* / Q000473:pathology; D021681:Scedosporium / Q000302:isolation & purification*
chemical_list: D000935:Antifungal Agents