title: Does kidney transplantation with multiple arteries affect graft survival?
abstract: BACKGROUND
  We compared short- and long-term outcomes of renal transplants with single versus multiple arteries.
  
  
  METHODS
  We retrospectively analyzed data from kidney transplants from 208 living donors performed between 1994 and 2010. Renal grafts were divided into two groups: single renal artery (n = 164) versus multiple renal arteries (n = 44). The groups were compared regarding early and late vascular and urological complications. Patient and graft survivals were compared using Kaplan-Meier survivorship curves with comparisons using the log-rank test.
  
  
  RESULTS
  Both groups were comparable regarding acute rejection episodes, posttransplant hypertension, postsurgery renal artery stenosis, and urologic complications. Only hemorrhagic complications and renal artery thrombosis were significantly higher in the multiple renal arteries group (P = .027 and .03, respectively). Warm ischemia time was significantly longer in the multiple renal arteries group without any influence on the incidence of acute tubular necrosis (P = .2). Mean creatinine clearance at 1 year was 65 versus 50 mL/min/1.73 m(2) (P = .5) and at 5 years, 60 versus 55 mL/min/1.73 m(2) (P = .1) for the single versus multiple renal arteries groups, respectively. Return to hemodialysis was necessary for 18.8% of the single and 16.1% of the multiple renal arteries group.
  
  
  CONCLUSIONS
  The use of an allograft with multiple renal arteries is a safe, successful surgical procedure, that does not influence patient or graft survivals or increase surgical complication rates provided the surgical team is evolved with technical skill.
authors.affiliation: Department of Urology, Habib Bourguiba Hospital, Sfax, Tunisia. k.chabchoub@laposte.net
authors.forename: K
authors.initials: K
authors.lastname: Chabchoub
authors.forename: M N
authors.initials: MN
authors.lastname: Mhiri
authors.forename: A
authors.initials: A
authors.lastname: Bahloul
authors.forename: S
authors.initials: S
authors.lastname: Fakhfakh
authors.forename: I
authors.initials: I
authors.lastname: Ben Hmida
authors.forename: M
authors.initials: M
authors.lastname: Hadj Slimen
authors.forename: W
authors.initials: W
authors.lastname: Charfi
authors.forename: M
authors.initials: M
authors.lastname: Abdennader
authors.forename: I
authors.initials: I
authors.lastname: Frikha
authors.forename: J
authors.initials: J
authors.lastname: Hachicha
mesh_terms: D000328:Adult; D000368:Aged; D064591:Allografts; D003404:Creatinine / Q000378:metabolism; D005260:Female; D006084:Graft Rejection; D006085:Graft Survival; D006801:Humans; D006973:Hypertension; D007511:Ischemia / Q000473:pathology; D007668:Kidney / Q000098:blood supply*; D016030:Kidney Transplantation / Q000379:methods*; D019520:Living Donors; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D012077:Renal Artery / Q000473:pathology; D012078:Renal Artery Obstruction / Q000473:pathology; D006435:Renal Dialysis; D051437:Renal Insufficiency / Q000628:therapy*; D012189:Retrospective Studies; D013927:Thrombosis; D016896:Treatment Outcome
chemical_list: D003404:Creatinine