title: Change in functional bowel symptoms after prostatectomy: a case-control study.
abstract: BACKGROUND
  Irritable bowel syndrome (IBS) is a chronic functional bowel disorder that up to 20% of the population is suffering from it. Also benign prostatic hyperplasia (BPH) is a common problem that approximately 90 percent of men may be affected by this condition until the eighth decade of their life. Prostatectomy as a surgery and pelvic intervention can cause IBS.
  
  
  METHODS
  It was a case-control study including 66 patients in 2 case groups and 66 patients in 2 control groups. Case groups were patients who underwent open prostatectomy and transurethral resection of the prostate (TURP) and control groups were patients who were candidate for prostatectomy.
  
  
  RESULTS
  Ten patients in case groups and five patients in control groups had IBS. There was no significant difference in IBS between control and case groups (p = 0.117).
  
  
  CONCLUSIONS
  This is the first forward study regarding bowel symptom changes following prostatectomy. The main positive finding of this study is that open prostatectomy was followed by significant increase in diarrhea and bowel habit alternation associated with onset of abdominal pain. Specifically the change was found after open operation but not after TURP. Prostatectomy whether in form of open or transurethral may cause onset of abdominal discomfort and bowel habit change.
authors.affiliation: Gastroenterology Section, Department of Internal Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
authors.forename: Peyman
authors.initials: P
authors.lastname: Adibi
authors.forename: Hamid
authors.initials: H
authors.lastname: Mazdak
authors.forename: Ali
authors.initials: A
authors.lastname: Derakhshandeh
authors.forename: Ali
authors.initials: A
authors.lastname: Toghiani
references.citation: Anesthesiology. 2000 Oct;93(4):1123-33
references.pmid: 11020770
references.citation: Q J Med. 1962 Jul;31:307-22
references.pmid: 13878459
references.citation: Aliment Pharmacol Ther. 2008 Aug 1;28(3):334-43
references.pmid: 19086237
references.citation: Gastroenterology. 2008 Jan;134(1):75-84
references.pmid: 18166349
references.citation: Clin J Pain. 2005 Sep-Oct;21(5):439-45
references.pmid: 16093750
references.citation: Gastroenterology. 1990 Aug;99(2):409-15
references.pmid: 2365191
references.citation: Gastroenterology. 2007 Jan;132(1):26-37
references.pmid: 17241857
references.citation: Scand J Gastroenterol. 1999 Nov;34(11):1144-52
references.pmid: 10582767
references.citation: Gastroenterology. 2004 Jun;126(7):1665-73
references.pmid: 15188159
references.citation: J Gastrointestin Liver Dis. 2009 Mar;18(1):67-71
references.pmid: 19337637
references.citation: Aliment Pharmacol Ther. 1999 May;13 Suppl 2:3-14
references.pmid: 10429736
references.citation: Dis Colon Rectum. 1997 Nov;40(11):1342-7
references.pmid: 9369110
references.citation: Gastroenterology. 1988 Jul;95(1):232-41
references.pmid: 3286362
references.citation: Gut. 1993 Aug;34(8):1108-11
references.pmid: 8174964
references.citation: Gut. 2007 May;56(5):655-60
references.pmid: 17440183
references.citation: Chin J Dig Dis. 2006;7(4):181-5
references.pmid: 17054578
references.citation: Dig Dis Sci. 2007 Aug;52(8):1810-3
references.pmid: 17410463
references.citation: Digestion. 1999 Jan-Feb;60(1):77-81
references.pmid: 9892803
references.citation: Gut. 1992 Jun;33(6):814-7
references.pmid: 1624165
references.citation: Aliment Pharmacol Ther. 1997 Feb;11(1):3-15
references.pmid: 9042970
references.citation: Urology. 1995 Sep;46(3 Suppl A):34-40
references.pmid: 7544515
references.citation: Dig Dis Sci. 1990 Oct;35(10):1285-90
references.pmid: 2145139