title: Osteoplastic bone metastasis in esophageal squamous cell cancer: report of a case.
abstract: This report presents a case of esophageal squamous cell cancer with osteoplastic bone metastasis. A 58-year-old male patient underwent multimodality treatment for esophageal cancer. Sclerotic changes resembling bone metastasis from prostate cancer were detected in the 4th thoracic and the 5th lumber vertebral body soon after the adjuvant chemoradiotherapy. Systemic examinations revealed no primary cancer as a cause of osteoplastic bone metastasis and no esophageal cancer recurrence. A needle biopsy revealed metastases of esophageal squamous cell cancer with osteoplastic changes. Multiple sclerotic changes were detected in the systemic bones at that time, and new carcinomatous bilateral pleural effusion developed. The drastic systemic progression of the cancer caused the rapid deterioration of the patient's general condition.
authors.affiliation: Department of Esophago-Gastric Surgery, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan. yasu.nakajima.srg1@tmd.ac.jp
authors.forename: Yasuaki
authors.initials: Y
authors.lastname: Nakajima
authors.forename: Shunsuke
authors.initials: S
authors.lastname: Ohta
authors.forename: Takuya
authors.initials: T
authors.lastname: Okada
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Miyawaki
authors.forename: Akihiro
authors.initials: A
authors.lastname: Hoshino
authors.forename: Tomoyoshi
authors.initials: T
authors.lastname: Suzuki
authors.forename: Kenro
authors.initials: K
authors.lastname: Kawada
authors.forename: Tetsuro
authors.initials: T
authors.lastname: Nishikage
authors.forename: Kagami
authors.initials: K
authors.lastname: Nagai
authors.forename: Keisuke
authors.initials: K
authors.lastname: Ae
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Kawachi
authors.forename: Tatsuyuki
authors.initials: T
authors.lastname: Kawano
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D018450:Disease Progression; D004938:Esophageal Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D008875:Middle Aged; D013125:Spinal Neoplasms / Q000556:secondary*
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