title: Treatment of cocaine overdose with lipid emulsion.
abstract: We describe the management and recovery of a 28-year-old man following a history of overdose by nasal inhalation of cocaine. The patient was presented in a comatose state suffering from seizures and marked cardiovascularly instability. Intravenous lipid emulsion was administered following initial resuscitation and tracheal intubation, as a means of treating persistent cardiac arrhythmias and profound hypotension. Following lipid emulsion therapy, the patient's life-threatening cardiovascular parameters rapidly improved and he recovered well without any side effects, thus being discharged within 2 days.
authors.affiliation: John Hammond Department of Anaesthesia, East Surrey Hospital, Redhill, UK. raveyshankar@yahoo.com
authors.forename: R
authors.initials: R
authors.lastname: Jakkala-Saibaba
authors.forename: P G
authors.initials: PG
authors.lastname: Morgan
authors.forename: G L
authors.initials: GL
authors.lastname: Morton
mesh_terms: D000328:Adult; D003042:Cocaine / Q000506:poisoning*; D062787:Drug Overdose / Q000188:drug therapy; D005217:Fat Emulsions, Intravenous / Q000627:therapeutic use*; D006801:Humans; D008297:Male
chemical_list: D005217:Fat Emulsions, Intravenous; D003042:Cocaine