title: Nucleobase recognition at alkaline pH and apparent pKa of single DNA bases immobilised within a biological nanopore.
abstract: The four DNA bases are recognized in immobilized DNA strands at high alkaline pH by nanopore current recordings. Ionic currents through the biological nanopores are also employed to measure the apparent pK(a) values of single nucleobases within the immobilised DNA strands.
authors.affiliation: Department of Chemistry, University of Leuven, 3001, Heverlee, Leuven, Belgium.
authors.forename: Lorenzo
authors.initials: L
authors.lastname: Franceschini
authors.forename: Ellina
authors.initials: E
authors.lastname: Mikhailova
authors.forename: Hagan
authors.initials: H
authors.lastname: Bayley
authors.forename: Giovanni
authors.initials: G
authors.lastname: Maglia
mesh_terms: D000468:Alkalies / Q000737:chemistry*; D004247:DNA / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D058608:Nanopores
chemical_list: D000468:Alkalies; D004247:DNA
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