title: Advancing PROMIS's methodology: results of the Third Patient-Reported Outcomes Measurement Information System (PROMIS(®)) Psychometric Summit.
abstract: In 2002, the NIH launched the 'Roadmap for Medical Research'. The Patient-Reported Outcomes Measurement Information System (PROMIS(®)) is one of the Roadmap's key aspects. To create the next generation of patient-reported outcome measures, PROMIS utilizes item response theory (IRT) and computerized adaptive testing. In 2009, the NIH funded the second wave of PROMIS studies (PROMIS II). PROMIS II studies continue PROMIS's agenda, but also include new features, including longitudinal analyses and more sociodemographically diverse samples. PROMIS II also includes increased emphasis on pediatric populations and evaluation of PROMIS item banks for clinical research and population science. These aspects bring new psychometric challenges. To address this, investigators associated with PROMIS gathered at the Third Psychometric Summit in September 2010 to identify, describe and discuss pressing psychometric issues and new developments in the field, as well as make analytic recommendations for PROMIS. The summit addressed five general themes: linking, differential item functioning, dimensionality, IRT models for longitudinal applications and new IRT software. In this article, we review the discussions and presentations that occurred at the Third PROMIS Psychometric Summit.
authors.affiliation: University of Cincinnati School of Medicine, James M Anderson Center for Health Systems Excellence, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, MLC 7014, Cincinnati, OH 45229, USA. adam.carle.cchmc@gmail.com
authors.forename: Adam C
authors.initials: AC
authors.lastname: Carle
authors.forename: David
authors.initials: D
authors.lastname: Cella
authors.forename: Li
authors.initials: L
authors.lastname: Cai
authors.forename: Seung W
authors.initials: SW
authors.lastname: Choi
authors.forename: Paul K
authors.initials: PK
authors.lastname: Crane
authors.forename: S McKay
authors.initials: SM
authors.lastname: Curtis
authors.forename: Jonathan
authors.initials: J
authors.lastname: Gruhl
authors.forename: Jin-Shei
authors.initials: JS
authors.lastname: Lai
authors.forename: Shubhabrata
authors.initials: S
authors.lastname: Mukherjee
authors.forename: Steven P
authors.initials: SP
authors.lastname: Reise
authors.forename: Jeanne A
authors.initials: JA
authors.lastname: Teresi
authors.forename: David
authors.initials: D
authors.lastname: Thissen
authors.forename: Eric J
authors.initials: EJ
authors.lastname: Wu
authors.forename: Ron D
authors.initials: RD
authors.lastname: Hays
mesh_terms: D006801:Humans; D007256:Information Systems; D015233:Models, Statistical; D017063:Outcome Assessment, Health Care; D011594:Psychometrics; D057566:Self Report; D012984:Software
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