title: Single pulse TMS induced disruption to right and left parietal cortex on addition and multiplication.
abstract: Whether or not mathematical operations are dependent on verbal codes in left hemisphere areas - particularly the left intraparietal sulcus - remains an issue of intense debate. Using single pulse transcranial magnetic stimulation directed at horizontal and ventral regions of the left and right intraparietal sulcus, we examined disruption to reaction times in simple addition and multiplication. Results indicate that these two operations differ in the pattern of lateralization across time for the two areas studied. These show that computational efficiency is not specifically dependent on left hemisphere regions and, in particular, that efficiency in multiplication is dependent on the ventral region of the intraparietal sulcus in the right hemisphere considered to be critical for motion representation and automatization.
authors.affiliation: Basque Center on Cognition Brain and Language, Donostia, Spain.
authors.forename: Elena
authors.initials: E
authors.lastname: Salillas
authors.forename: Carlo
authors.initials: C
authors.lastname: Semenza
authors.forename: Demis
authors.initials: D
authors.lastname: Basso
authors.forename: Tomaso
authors.initials: T
authors.lastname: Vecchi
authors.forename: Michael
authors.initials: M
authors.lastname: Siegal
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D008433:Mathematics; D010296:Parietal Lobe / Q000502:physiology*; D050781:Transcranial Magnetic Stimulation; D055815:Young Adult