title: Stroke associated with surgical and transcatheter treatment of aortic stenosis: a comprehensive review.
abstract: Stroke is a potential complication of treating patients with aortic stenosis via surgical aortic valve replacement (AVR), transcatheter aortic valve replacement (TAVR), and balloon aortic valvuloplasty. Because there are limited and heterogeneous data on the incidence, risk factors, and outcomes of stroke among patients being treated for aortic stenosis, we performed a comprehensive review of the literature. The risk of stroke after AVR in the general population is approximately 1.5%, and the risk is increased (to approximately 2% to 4%) in older and higher-risk patients. Strokes were reported in 1.5% to 6% of patients treated with TAVR, and in the only randomized trial of AVR versus TAVR, there was an increased risk of 30-day strokes (minor and major strokes and transient ischemic attacks) with TAVR (5.5% vs. 2.4%, p = 0.04).
authors.affiliation: Columbia University Medical Center/New York-Presbyterian Hospital, and the Cardiovascular Research Foundation, New York, NY, USA.
authors.forename: Benoit
authors.initials: B
authors.lastname: Daneault
authors.forename: Ajay J
authors.initials: AJ
authors.lastname: Kirtane
authors.forename: Susheel K
authors.initials: SK
authors.lastname: Kodali
authors.forename: Mathew R
authors.initials: MR
authors.lastname: Williams
authors.forename: Philippe
authors.initials: P
authors.lastname: Genereux
authors.forename: George R
authors.initials: GR
authors.lastname: Reiss
authors.forename: Craig R
authors.initials: CR
authors.lastname: Smith
authors.forename: Jeffrey W
authors.initials: JW
authors.lastname: Moses
authors.forename: Martin B
authors.initials: MB
authors.lastname: Leon
mesh_terms: D001024:Aortic Valve Stenosis / Q000601:surgery*; D006328:Cardiac Catheterization / Q000009:adverse effects*; D005500:Follow-Up Studies; D019918:Heart Valve Prosthesis Implantation / Q000009:adverse effects* / Q000379:methods; D006801:Humans; D015994:Incidence; D012307:Risk Factors; D020521:Stroke / Q000453:epidemiology / Q000209:etiology*; D014481:United States / Q000453:epidemiology