title: tert-Butyl N-((1S)-2-hy-droxy-1-{N'-[(E)-2-hy-droxy-4-meth-oxy-benzyl-idene]hydrazinecarbon-yl}eth-yl)carbamate.
abstract: The mol-ecule of the title compound, C(16)H(23)N(3)O(6), is twisted about the chiral C atom with the dihedral angle formed between the amide residues being 76.9 (3)°. Overall, the mol-ecule is curved with the terminal organic groups lying to the same side. The conformation about the imine bond [1.291 (5) Å] is E and an intra-molecular O-H⋯N hydrogen bond generates an S(6) ring. In the crystal, O-H⋯O and N-H⋯O hydrogen bonds involving the hy-droxy, amine and carbonyl groups lead to the formation of supra-molecular layers, which stack along the c-axis direction.
authors.forename: James L
authors.initials: JL
authors.lastname: Wardell
authors.forename: Marcus V N
authors.initials: MV
authors.lastname: de Souza
authors.forename: Alessandra C
authors.initials: AC
authors.lastname: Pinheiro
authors.forename: Edward R T
authors.initials: ER
authors.lastname: Tiekink
authors.forename: Solange M S V
authors.initials: SM
authors.lastname: Wardell
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