title: [Follow-up of our patients with transposition of the great arteries and arterial switch operation; comparison of simple and complex transposition cases].
abstract: OBJECTIVE
  1. Follow-up data of patients with simple transposition of great arteries (TGA) and TGA with ventricular septal defect (VSD), who had arterial switch operation (ASO) are compared. 2. Factors affecting mortality and morbidity after ASO are described.
  
  
  METHODS
  Seventy-six patients, who had an ASO between April 2007 and August 2010 were studied retrospectively. The patients with intact ventricular septum (IVS) (n=36) were in Group 1, and those with VSD (n=40) in Group 2. The pre and postoperative clinical and echocardiographic variables and intensive care unit (ICU) outcomes were compared among groups using Mann-Whitney U, Pearson correlation and logistic regression tests.
  
  
  RESULTS
  The mean age at operation was 44.1 days, weight was 3.6±0.98 kg. Patients were followed for 15.5±11.21 months. The aortic cross-clamp (AoCC) and cardiopulmonary bypass (CPB) times were higher in patients with VSD (p=0.001, p=0.004). Patients in Group 1 had longer inotropic agent infusion (p=0.001). Length of stay in ICU was similar in two groups (p>0.05). There was no correlation between the length of stay in ICU and age, weight, CPB time, AoCC time. Aortic regurgitation was more frequent in Group 2 (p=0.02). During follow-up, 12 patients died (15.7%), and 8 patients had a revision operation (10.5%) (diaphragmatic plication in 4, pulmonary artery reconstruction in 1, recoarctation operation in 3 patients). Mortality was similar in groups (p>0.05).
  
  
  CONCLUSIONS
  Arterial switch operation provides anatomical correction in TGA. Appropriate timing and good perioperative planning facilitates low morbidity and mortality in patients with VSD as in patients with simple TGA.
authors.affiliation: Başkent Üniversitesi Tıp Fakültesi, İstanbul Sağlık Uygulama ve Araştırma Merkezi, Pediyatrik Kardiyoloji, Altunizade, İstanbul, Turkey.
authors.forename: Osman
authors.initials: O
authors.lastname: Akdeniz
authors.forename: Canan
authors.initials: C
authors.lastname: Ayabakan
authors.forename: Uygar
authors.initials: U
authors.lastname: Yörüker
authors.forename: Kürşad
authors.initials: K
authors.lastname: Tokel
authors.forename: Ozlem
authors.initials: O
authors.lastname: Sarısoy
authors.forename: Rıza
authors.initials: R
authors.lastname: Türköz
authors.forename: Can
authors.initials: C
authors.lastname: Vuran
authors.forename: Bülent
authors.initials: B
authors.lastname: Sarıtaş
authors.forename: Cağrı
authors.initials: C
authors.lastname: Günaydın
authors.forename: Emre
authors.initials: E
authors.lastname: Ozker
mesh_terms: D001024:Aortic Valve Stenosis / Q000000981:diagnostic imaging; D006348:Cardiac Surgical Procedures / Q000379:methods; D004452:Echocardiography; D005260:Female; D005500:Follow-Up Studies; D006345:Heart Septal Defects, Ventricular / Q000150:complications / Q000401:mortality / Q000601:surgery*; D017052:Hospital Mortality; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007902:Length of Stay; D016015:Logistic Models; D008297:Male; D011183:Postoperative Complications / Q000000981:diagnostic imaging; D012189:Retrospective Studies; D012307:Risk Factors; D012720:Severity of Illness Index; D014188:Transposition of Great Vessels / Q000150:complications / Q000401:mortality / Q000601:surgery*; D014421:Turkey