title: [A case of repeated bone metastases of breast carcinoma successfully treated by S-1 chemotherapy].
abstract: We report a case of breast carcinoma with repeated recurrences in the right bone. The recurrent site of the bone was treated by radiation therapy with a total of 3 7. 5 Gy irradiation, and chemotherapy with the CMF regimen. After 2 years, recurrence was suspected in the same region because there was an elevation of the NCC-ST-439 tumor marker. We carried out chemotherapy with S-1 100mg/body/day. The NCC-ST-439 value returned to within the normal range after 3 months' administration of S -1, and continued in the normal value for 20 months.
authors.affiliation: Dept. of Surgery, Jikei University School of Medicine, Japan.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Takeyama
authors.forename: Shigeya
authors.initials: S
authors.lastname: Kyoda
authors.forename: Akinori
authors.initials: A
authors.lastname: Yamashita
authors.forename: Satoki
authors.initials: S
authors.lastname: Kinoshita
authors.forename: Tomoyoshi
authors.initials: T
authors.lastname: Okamoto
authors.forename: Ken
authors.initials: K
authors.lastname: Uchida
authors.forename: Toshiaki
authors.initials: T
authors.lastname: Morikawa
mesh_terms: D000964:Antimetabolites, Antineoplastic / Q000627:therapeutic use*; D001859:Bone Neoplasms / Q000188:drug therapy* / Q000556:secondary; D001943:Breast Neoplasms / Q000188:drug therapy* / Q000473:pathology; D004338:Drug Combinations; D005260:Female; D006801:Humans; D008875:Middle Aged; D010094:Oxonic Acid / Q000627:therapeutic use*; D012074:Remission Induction; D005641:Tegafur / Q000627:therapeutic use*
chemical_list: D000964:Antimetabolites, Antineoplastic; D004338:Drug Combinations; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid