title: The predictive value of physical examination findings in patients with suspected acute heart failure syndrome.
abstract: It can be difficult to differentiate acute heart failure syndrome (AHFS) from other causes of acute dyspnea, especially when patients present in extremis. The objective of the study was to determine the predictive value of physical examination findings for pulmonary edema and elevated B-type natriuretic peptide (BNP) levels in patients with suspected AHFS. This was a secondary analysis of a previously reported prospective study of jugular vein ultrasonography in patients with suspected AHFS. Charts were reviewed for physical examination findings, which were then compared to pulmonary edema on chest radiography (CXR) read by radiologists blinded to clinical information and BNP levels measured at presentation. The predictive value of every sign and combination of signs for pulmonary edema on CXR or an elevated BNP was poor. Since physical examination findings alone are not predictive of pulmonary edema or an elevated BNP, clinicians should have a low threshold for using CXR or BNP in clinical evaluation. This brief research report suggests that no physical examination finding or constellation of findings can be used to reliably predict pulmonary edema or an elevated BNP in patients with suspected AHFS.
authors.affiliation: Division of Emergency Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA. tbj@ucla.edu
authors.forename: Timothy B
authors.initials: TB
authors.lastname: Jang
authors.forename: Chandra
authors.initials: C
authors.lastname: Aubin
authors.forename: Rosanne
authors.initials: R
authors.lastname: Naunheim
authors.forename: Lawrence M
authors.initials: LM
authors.lastname: Lewis
authors.forename: Amy H
authors.initials: AH
authors.lastname: Kaji
mesh_terms: D000368:Aged; D016001:Confidence Intervals; D005260:Female; D006333:Heart Failure / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D007601:Jugular Veins / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D020097:Natriuretic Peptide, Brain / Q000097:blood; D010808:Physical Examination / Q000379:methods*; D011237:Predictive Value of Tests; D011379:Prognosis; D011654:Pulmonary Edema; D012307:Risk Factors; D013577:Syndrome
chemical_list: D020097:Natriuretic Peptide, Brain
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