title: Recurrent uveitis due to sildenafil usage in a patient with Behçet's disease.
abstract: Behçet's disease (BD) may cause uveitis and retinal vasculitis in nearly half of the patients. Uveitis is one of the most serious complications that can lead to blindness. Sildenafil (Viagra(R)) and the other phosphodiesterase type 5 (PDE5) inhibitors are the first-line options for the treatment of erectile dysfunction, but transient visual symptoms and serious ocular side effects have been reported in PDE5 inhibitor users. Herein, we report a case with BD who applied to our outpatient unit with recurrent uveitis after sildenafil therapy.
authors.affiliation: Department of Internal Medicine, Hacettepe University Hospital, Sihhiye, Ankara, Turkey. metin1721978@yahoo.com
authors.forename: Metin
authors.initials: M
authors.lastname: Işık
authors.forename: Levent
authors.initials: L
authors.lastname: Kılıç
authors.forename: Ismail
authors.initials: I
authors.lastname: Doğan
mesh_terms: D000328:Adult; D001528:Behcet Syndrome / Q000150:complications*; D006801:Humans; D008297:Male; D058986:Phosphodiesterase 5 Inhibitors / Q000009:adverse effects*; D010879:Piperazines / Q000009:adverse effects*; D011687:Purines / Q000009:adverse effects; D012008:Recurrence; D000068677:Sildenafil Citrate; D013450:Sulfones / Q000009:adverse effects*; D014605:Uveitis / Q000139:chemically induced*
chemical_list: D058986:Phosphodiesterase 5 Inhibitors; D010879:Piperazines; D011687:Purines; D013450:Sulfones; D000068677:Sildenafil Citrate
references.citation: Drugs. 2007;67(1):75-93
references.pmid: 17209665
references.citation: Ann Rheum Dis. 2008 Dec;67(12):1656-62
references.pmid: 18245110