title: Psoriasis and the pregnant woman: what are the key considerations?
abstract: Pregnancy is characterized by multiple physiologic changes. During the entire gestational period, both mother and infant are vulnerable to a variety of external and internal factors. Maternal disease, use of certain medications, drugs, alcohol, smoking, and radiation exposure can have devastating effects on the fetus. Pregnancy-related complications in women with psoriasis can be caused by both the disease and the treatment. The response of the maternal placenta to psoriasis-induced inflammation and comorbid conditions, such as obesity, hypertension, and depression, may also influence the pregnancy. Herein, we review the relationship between psoriasis and undesirable pregnancy outcomes.
authors.affiliation: DermSurgery Associates, Houston, TX, USA.
authors.forename: Jennifer L
authors.initials: JL
authors.lastname: Landau
authors.forename: Megan N
authors.initials: MN
authors.lastname: Moody
authors.forename: Natalia
authors.initials: N
authors.lastname: Kazakevich
authors.forename: Leonard H
authors.initials: LH
authors.lastname: Goldberg
mesh_terms: D005260:Female; D006801:Humans; D010920:Placenta / Q000378:metabolism; D011247:Pregnancy; D011248:Pregnancy Complications / Q000453:epidemiology*; D011256:Pregnancy Outcome / Q000453:epidemiology*; D011565:Psoriasis / Q000150:complications* / Q000628:therapy; D012307:Risk Factors