title: [Revisiting the dose-effect correlations in irradiated head and neck cancer using automatic segmentation tools of the dental structures, mandible and maxilla].
abstract: OBJECTIVE
  Manual delineation of dental structures is too time-consuming to be feasible in routine practice. Information on dose risk levels is crucial for dentists following irradiation of the head and neck to avoid postextraction osteoradionecrosis based on empirical dose-effects data established on bidimensional radiation therapy plans.
  
  
  METHODS
  We present an automatic atlas-based segmentation framework of the dental structures, called Dentalmaps, constructed from a patient image-segmentation database.
  
  
  RESULTS
  This framework is accurate (within 2 Gy accuracy) and relevant for the routine use. It has the potential to guide dental care in the context of new irradiation techniques.
  
  
  CONCLUSIONS
  This tool provides a user-friendly interface for dentists and radiation oncologists in the context of irradiated head and neck cancer patients. It will likely improve the knowledge of dose-effect correlations for dental complications and osteoradionecrosis.
authors.affiliation: Département de Radiothérapie, Centre Antoine-Lacassagne, 33, avenue de Valombrose, 06189 Nice cedex 2, France. jthariat@hotmail.com
authors.forename: J
authors.initials: J
authors.lastname: Thariat
authors.forename: L
authors.initials: L
authors.lastname: Ramus
authors.forename: G
authors.initials: G
authors.lastname: Odin
authors.forename: S
authors.initials: S
authors.lastname: Vincent
authors.forename: V
authors.initials: V
authors.lastname: Darcourt
authors.forename: M-H
authors.initials: MH
authors.lastname: Orlanducci
authors.forename: O
authors.initials: O
authors.lastname: Dassonville
authors.forename: A
authors.initials: A
authors.lastname: Lacout
authors.forename: P-Y
authors.initials: PY
authors.lastname: Marcy
authors.forename: G
authors.initials: G
authors.lastname: Cagnol
authors.forename: G
authors.initials: G
authors.lastname: Malandain
mesh_terms: D006258:Head and Neck Neoplasms / Q000532:radiotherapy*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008334:Mandible / Q000033:anatomy & histology*; D008437:Maxilla / Q000033:anatomy & histology*; D011879:Radiotherapy Dosage; D014070:Tooth / Q000033:anatomy & histology*