title: Breast cancer: overview & updates.
abstract: Breast cancer is a complex disease and treatment recommendations are continually changing. It is the leading cancer in women and the second leading cause of cancer mortality. This overview of breast cancer will discuss pathologic features, local and systemic treatment considerations, endocrine therapy, metastatic treatment regimens, and follow-up for optimal breast health. Recent approvals that advance the treatment of metastatic breast cancer are also addressed.
authors.affiliation: UniversityHospitals Case Medical Center, Seidman Cancer Center, Cleveland, OH, USA.
authors.forename: Catherine
authors.initials: C
authors.lastname: Downs-Holmes
authors.forename: Paula
authors.initials: P
authors.lastname: Silverman
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use; D018931:Antineoplastic Agents, Hormonal / Q000627:therapeutic use; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001943:Breast Neoplasms / Q000401:mortality / Q000473:pathology / Q000628:therapy*; D017024:Chemotherapy, Adjuvant / Q000639:trends; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D020360:Neoadjuvant Therapy / Q000639:trends; D017410:Practice Guidelines as Topic; D012307:Risk Factors; D015996:Survival Rate
chemical_list: D000970:Antineoplastic Agents; D018931:Antineoplastic Agents, Hormonal