title: Gram-scale synthesis of the A'B'-subunit of angelmicin B.
abstract: A gram-scale enantiospecific synthesis of the A'B'-subunit of angelmicin B is reported. The synthesis involves a Lewis acid catalyzed contrasteric Diels-Alder reaction and a tandem silyl zincate 1,6-addition/enolate oxidation sequence.
authors.affiliation: Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, Massachusetts 02138, USA.
authors.forename: Benjamin C
authors.initials: BC
authors.lastname: Milgram
authors.forename: Brian B
authors.initials: BB
authors.lastname: Liau
authors.forename: Matthew D
authors.initials: MD
authors.lastname: Shair
mesh_terms: D039903:Actinobacteria / Q000737:chemistry; D000880:Anthraquinones / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D058116:Lewis Acids / Q000737:chemistry; D015394:Molecular Structure; D017646:Organosilicon Compounds / Q000737:chemistry; D010084:Oxidation-Reduction; D013237:Stereoisomerism
chemical_list: D000880:Anthraquinones; D058116:Lewis Acids; D017646:Organosilicon Compounds; C083655:angelmicin B
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