title: The phenomenology of autistic regression: subtypes and associated factors.
abstract: This study aimed to investigate the association of autistic regression (AR) and subtypes of AR with medical, developmental and psychiatric factors. Fifty-seven children with autistic spectrum disorders (ASD) were included in the study. Two types of AR are defined as regression after a normal social/language development (type 1) and regression as the worsening of previously reported autistic features (type 2). The frequency of history of AR was 56.1%. Male gender and sleep problems were found to be associated with a positive history of AR. The frequency of gastrointestinal complaints/diseases was higher in children with regression type 2 when compared to the children with regression type 1. Future studies with larger sample size and prospective design will contribute to clarifying the phenomenology and the associated factors of AR.
authors.affiliation: Antakya Hospital of Child Care, Hatay, Turkey. ozalpekinci@yahoo.com
authors.forename: Ozalp
authors.initials: O
authors.lastname: Ekinci
authors.forename: Ayse Rodopman
authors.initials: AR
authors.lastname: Arman
authors.forename: Ismet
authors.initials: I
authors.lastname: Melek
authors.forename: Yasin
authors.initials: Y
authors.lastname: Bez
authors.forename: Meral
authors.initials: M
authors.lastname: Berkem
mesh_terms: D000293:Adolescent; D002648:Child; D002659:Child Development Disorders, Pervasive / Q000145:classification* / Q000150:complications / Q000503:physiopathology; D002675:Child, Preschool; D005260:Female; D005767:Gastrointestinal Diseases / Q000209:etiology; D006801:Humans; D007858:Learning / Q000145:classification; D008297:Male; D011569:Psychiatric Status Rating Scales; D012043:Regression, Psychology; D012737:Sex Factors; D012893:Sleep Wake Disorders / Q000209:etiology; D014888:Wechsler Scales
references.citation: Dev Med Child Neurol. 2006 Jul;48(7):604-8
references.pmid: 16780632
references.citation: J Am Acad Child Psychiatry. 1985 Mar;24(2):191-6
references.pmid: 3989162
references.citation: J Autism Dev Disord. 2005 Dec;35(6):713-27
references.pmid: 16267642
references.citation: Jpn J Psychiatry Neurol. 1987 Jun;41(2):237-45
references.pmid: 3437611
references.citation: Sleep. 2006 Dec;29(12):1563-71
references.pmid: 17252887
references.citation: Pediatrics. 1997 Apr;99(4):560-6
references.pmid: 9093299
references.citation: Dev Med Child Neurol. 1999 Jan;41(1):60-6
references.pmid: 10068053
references.citation: J Autism Dev Disord. 2000 Apr;30(2):113-9
references.pmid: 10832775
references.citation: Pediatr Neurol. 2001 Mar;24(3):183-9
references.pmid: 11301218
references.citation: J Autism Dev Disord. 2004 Dec;34(6):731-4
references.pmid: 15679193
references.citation: J Autism Dev Disord. 2006 Aug;36(6):741-52
references.pmid: 16897403
references.citation: Autism. 2009 Jul;13(4):357-74
references.pmid: 19535466
references.citation: J Sleep Res. 2008 Jun;17(2):197-206
references.pmid: 18482108
references.citation: Sleep Med. 2010 Aug;11(7):659-64
references.pmid: 20605110
references.citation: Pediatrics. 1991 Dec;88(6):1211-8
references.pmid: 1956739
references.citation: Am J Ment Defic. 1985 Mar;89(5):485-91
references.pmid: 3993694
references.citation: Ment Retard Dev Disabil Res Rev. 2004;10(2):144-9
references.pmid: 15362173
references.citation: Child Psychiatry Hum Dev. 2009 Mar;40(1):99-110
references.pmid: 18600444
references.citation: J Autism Dev Disord. 1980 Mar;10(1):91-103
references.pmid: 6927682
references.citation: Ment Retard Dev Disabil Res Rev. 2004;10(2):139-43
references.pmid: 15362172
references.citation: J Autism Dev Disord. 2003 Dec;33(6):607-16
references.pmid: 14714930
references.citation: J Autism Dev Disord. 2008 Nov;38(10):1827-36
references.pmid: 18449635
references.citation: J Child Psychol Psychiatry. 1980 Jul;21(3):221-9
references.pmid: 7430288
references.citation: J Autism Dev Disord. 2008 Nov;38(10):1888-97
references.pmid: 18483842
references.citation: J Child Neurol. 2005 Jan;20(1):27-31
references.pmid: 15791919
references.citation: Autism. 2005 Dec;9(5):461-86
references.pmid: 16287700
references.citation: J Autism Dev Disord. 2007 Mar;37(3):580-8
references.pmid: 16909312
references.citation: Epilepsia. 2009 Aug;50 Suppl 7:18-20
references.pmid: 19682044
references.citation: BMJ. 2002 Feb 16;324(7334):393-6
references.pmid: 11850369
references.citation: Acta Psychiatr Scand. 1998 Oct;98(4):296-303
references.pmid: 9821451
references.citation: J Autism Dev Disord. 2006 Apr;36(3):299-316
references.pmid: 16729252
references.citation: J Child Psychol Psychiatry. 2004 Jul;45(5):936-55
references.pmid: 15225337