title: How to use serum ammonia.
abstract: Hyperammonaemia is a potentially extremely important indicator of impairment in intermediate metabolism. However, lack of experience in sample handling and confusion about what level is significant, can lead to its devaluation as a test. The aim of this article is to help the non-metabolic specialist to decide when it is appropriate to investigate for hyperammonaemia, to discuss potential investigatory pitfalls and to help in interpretation of results.
authors.affiliation: Metabolic Medicine Unit, Great Ormond Street Hospital for Children with UCL Institute of Child Health, London, UK. Brooma@gosh.nhs.uk
authors.forename: Alexander
authors.initials: A
authors.lastname: Broomfield
authors.forename: Stephanie
authors.initials: S
authors.lastname: Grunewald
mesh_terms: D000641:Ammonia / Q000097:blood*; D002648:Child; D002675:Child, Preschool; D004502:Education, Medical, Continuing; D006801:Humans; D022124:Hyperammonemia / Q000097:blood* / Q000175:diagnosis* / Q000453:epidemiology; D007223:Infant; D008659:Metabolic Diseases / Q000097:blood* / Q000175:diagnosis* / Q000453:epidemiology; D011379:Prognosis; D012307:Risk Factors
chemical_list: D000641:Ammonia