title: Isolated congenital megacystis without intestinal obstruction: a mild variant of chronic intestinal pseudoobstruction syndrome?
abstract: Megacystis is frequently involved with chronic intestinal pseudoobstruction syndrome; however, isolated megacystis without intestinal obstruction is extremely rare. We present the case of a female patient with isolated congenital megacystis without severe intestinal obstruction. In this case, barium enema did not reveal any significant findings; however, histologic evaluation of her rectum showed hypoganglionosis of the submucous and myenteric plexuses. These findings indicate that this case may be a mild variant of chronic intestinal pseudoobstruction syndrome. The presence of megacystis should alert the physician to the possibility of chronic intestinal pseudoobstruction syndrome.
authors.affiliation: Department of Pediatrics, School of Medicine, Institute of Medical, Pharmaceutical, and Health Sciences, Kanazawa University, 13-1 Takaramachi, Kanazawa 920-8641, Japan. shimizum@staff.kanazawa-u.ac.jp
authors.forename: Masaki
authors.initials: M
authors.lastname: Shimizu
authors.forename: Sayaka
authors.initials: S
authors.lastname: Nishio
authors.forename: Kazuyuki
authors.initials: K
authors.lastname: Ueno
authors.forename: Tadafumi
authors.initials: T
authors.lastname: Yokoyama
authors.forename: Seisho
authors.initials: S
authors.lastname: Sakai
authors.forename: Shuya
authors.initials: S
authors.lastname: Nagaoki
authors.forename: Naotoshi
authors.initials: N
authors.lastname: Sugimoto
authors.forename: Kazuhide
authors.initials: K
authors.lastname: Ohta
authors.forename: Masatoshi
authors.initials: M
authors.lastname: Miyamoto
authors.forename: Akihiro
authors.initials: A
authors.lastname: Yachie
mesh_terms: D001466:Barium Sulfate; D004386:Duodenum / Q000002:abnormalities / Q000000981:diagnostic imaging; D004733:Enema; D005260:Female; D005315:Fetal Diseases / Q000145:classification* / Q000000981:diagnostic imaging; D006627:Hirschsprung Disease / Q000175:diagnosis / Q000473:pathology*; D006801:Humans; D007418:Intestinal Pseudo-Obstruction / Q000145:classification / Q000209:etiology*; D008279:Magnetic Resonance Imaging; D009197:Myenteric Plexus / Q000002:abnormalities*; D011877:Radionuclide Imaging; D013368:Submucous Plexus / Q000002:abnormalities*; D016216:Ultrasonography, Prenatal; D001743:Urinary Bladder / Q000002:abnormalities / Q000000981:diagnostic imaging
chemical_list: D001466:Barium Sulfate