title: Regions identity between the genome of vertebrates and non-retroviral families of insect viruses.
abstract: BACKGROUND
  The scope of our understanding of the evolutionary history between viruses and animals is limited. The fact that the recent availability of many complete insect virus genomes and vertebrate genomes as well as the ability to screen these sequences makes it possible to gain a new perspective insight into the evolutionary interaction between insect viruses and vertebrates. This study is to determine the possibility of existence of sequence identity between the genomes of insect viruses and vertebrates, attempt to explain this phenomenon in term of genetic mobile element, and try to investigate the evolutionary relationship between these short regions of identity among these species.
  
  
  RESULTS
  Some of studied insect viruses contain variable numbers of short regions of sequence identity to the genomes of vertebrate with nucleotide sequence length from 28 bp to 124 bp. They are found to locate in multiple sites of the vertebrate genomes. The ontology of animal genes with identical regions involves in several processes including chromatin remodeling, regulation of apoptosis, signaling pathway, nerve system development and some enzyme-like catalysis. Phylogenetic analysis reveals that at least some short regions of sequence identity in the genomes of vertebrate are derived the ancestral of insect viruses.
  
  
  CONCLUSIONS
  Short regions of sequence identity were found in the vertebrates and insect viruses. These sequences played an important role not only in the long-term evolution of vertebrates, but also in promotion of insect virus. This typical win-win strategy may come from natural selection.
authors.affiliation: National Center for Clinical Laboratories, Beijing Hospital, Beijing, China.
authors.forename: Gaowei
authors.initials: G
authors.lastname: Fan
authors.forename: Jinming
authors.initials: J
authors.lastname: Li
mesh_terms: D000818:Animals; D019143:Evolution, Molecular; D022761:Gene Transfer, Horizontal; D007304:Insect Viruses / Q000235:genetics*; D020071:Interspersed Repetitive Sequences; D017385:Sequence Homology; D014714:Vertebrates / Q000235:genetics*
references.citation: Bioinformatics. 2007 Nov 1;23(21):2947-8
references.pmid: 17846036
references.citation: Genome Res. 2007 Jul;17(7):992-1004
references.pmid: 17495012
references.citation: J Gen Virol. 2006 Dec;87(Pt 12):3567-3575
references.pmid: 17098972
references.citation: Trends Genet. 2004 Feb;20(2):62-7
references.pmid: 14746985
references.citation: Rev Invest Clin. 2009 Sep-Oct;61(5):412-27
references.pmid: 20184102
references.citation: Proc Natl Acad Sci U S A. 2010 Nov 9;107(45):19508-13
references.pmid: 20974979
references.citation: Curr Opin Genet Dev. 2003 Dec;13(6):651-8
references.pmid: 14638329
references.citation: Genome Res. 2002 Nov;12(11):1739-48
references.pmid: 12421761
references.citation: Curr Microbiol. 2011 Mar;62(3):770-6
references.pmid: 20972791
references.citation: Intervirology. 2009;52(4):196-200
references.pmid: 19546577
references.citation: Immunol Cell Biol. 2001 Feb;79(1):62-6
references.pmid: 11168625
references.citation: J Mol Biol. 2002 May 17;318(5):1155-74
references.pmid: 12083509
references.citation: J Virol. 2007 Sep;81(17):9437-42
references.pmid: 17581995
references.citation: Uirusu. 2010 Dec;60(2):143-53
references.pmid: 21488328
references.citation: FEBS Lett. 2000 Feb 25;468(2-3):109-14
references.pmid: 10692568
references.citation: Mol Biol Evol. 1999 Jun;16(6):806-16
references.pmid: 10368958
references.citation: Proc Natl Acad Sci U S A. 2006 Sep 26;103(39):14390-5
references.pmid: 16980413
references.citation: J Hum Genet. 2006;51(4):353-362
references.pmid: 16518567
references.citation: PLoS One. 2011 Apr 29;6(4):e18935
references.pmid: 21559486
references.citation: J Biol Chem. 2000 Oct 6;275(40):31514-9
references.pmid: 10908563
references.citation: Curr Opin Microbiol. 2000 Aug;3(4):371-8
references.pmid: 10972497
references.citation: Nature. 2010 Jan 7;463(7277):84-7
references.pmid: 20054395
references.citation: Trends Microbiol. 2005 Jun;13(6):278-84
references.pmid: 15936660
references.citation: Nature. 2010 Jan 7;463(7277):39-40
references.pmid: 20054386
references.citation: Silence. 2010 Jul 08;1(1):14
references.pmid: 20615220