title: Pre-steady-state kinetics of interaction of wild-type and multiple drug-resistant HIV protease with first and second generation inhibitory drugs.
authors.affiliation: Institute of Chemical Biology and Fundamental Medicine, Russian Academy of Sciences, Novosibirsk, Russia.
authors.forename: N A
authors.initials: NA
authors.lastname: Kuznetsov
authors.forename: A V
authors.initials: AV
authors.lastname: Kozyr
authors.forename: M A
authors.initials: MA
authors.lastname: Dronina
authors.forename: I V
authors.initials: IV
authors.lastname: Smirnov
authors.forename: E N
authors.initials: EN
authors.lastname: Kaliberda
authors.forename: A G
authors.initials: AG
authors.lastname: Mikhailova
authors.forename: L D
authors.initials: LD
authors.lastname: Rumsh
authors.forename: O S
authors.initials: OS
authors.lastname: Fedorova
authors.forename: A G
authors.initials: AG
authors.lastname: Gabibov
authors.forename: A V
authors.initials: AV
authors.lastname: Kolesnikov
mesh_terms: D019943:Amino Acid Substitution / Q000235:genetics; D000069454:Darunavir; D015195:Drug Design; D018432:Drug Resistance, Multiple / Q000235:genetics*; D005456:Fluorescent Dyes / Q000494:pharmacology; D016333:HIV Protease / Q000737:chemistry / Q000235:genetics* / Q000378:metabolism; D017320:HIV Protease Inhibitors / Q000494:pharmacology*; D006801:Humans; D019469:Indinavir / Q000494:pharmacology*; D007700:Kinetics; D056004:Molecular Dynamics Simulation; D009154:Mutation / Q000235:genetics*; D013449:Sulfonamides / Q000494:pharmacology*
chemical_list: D005456:Fluorescent Dyes; D017320:HIV Protease Inhibitors; D013449:Sulfonamides; D019469:Indinavir; D016333:HIV Protease; D000069454:Darunavir
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