title: Au-catalyzed piperidine synthesis via tandem acyloxy migration/intramolecular [3 + 2] cycloaddition of enynyl esters.
abstract: An Au-catalyzed tandem protocol involving enynyl ester isomerization and subsequent intramolecular [3 + 2] cyclization has been developed. This strategy provides an efficient approach for the synthesis of polyfunctional piperidines, which are subunits of many bioactive molecules.
authors.affiliation: State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Gansu 730000, People's Republic of China.
authors.forename: Huaiji
authors.initials: H
authors.lastname: Zheng
authors.forename: Xing
authors.initials: X
authors.lastname: Huo
authors.forename: Changgui
authors.initials: C
authors.lastname: Zhao
authors.forename: Peng
authors.initials: P
authors.lastname: Jing
authors.forename: Juan
authors.initials: J
authors.lastname: Yang
authors.forename: Bowen
authors.initials: B
authors.lastname: Fang
authors.forename: Xuegong
authors.initials: X
authors.lastname: She
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D003500:Cyclization; D004952:Esters; D006046:Gold / Q000737:chemistry*; D015394:Molecular Structure; D010880:Piperidines / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D000480:Alkynes; D004952:Esters; D010880:Piperidines; D006046:Gold