title: Romiplostim efficacy in an acute myeloid leukemia patient with transfusion refractory thrombocytopenia.
abstract: BACKGROUND
  Refractoriness to platelet (PLT) transfusion is a feared, life-threatening complication in hematology-oncology patients. Despite increased PLT requirement and treatment costs, the clinical management is difficult and these patients had less favorable outcomes.
  
  
  METHODS
  We report on the efficacy of the thrombopoietic agent romiplostim in a patient with acute myeloid leukemia with chemotherapy-induced transfusion-refractory thrombocytopenia.
  
  
  CONCLUSIONS
  Romiplostim could be very helpfull in the management of AML patients with transfusion refractory thrombocytopenia.
authors.affiliation: Division of Hematology and Clinical Pharmacy, Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, Canada.
authors.forename: Maxime
authors.initials: M
authors.lastname: Berthelot-Richer
authors.forename: Brigitte
authors.initials: B
authors.lastname: Boilard
authors.forename: Annie
authors.initials: A
authors.lastname: Morin
authors.forename: Brigitte
authors.initials: B
authors.lastname: Bolduc
authors.forename: Patrice
authors.initials: P
authors.lastname: Beauregard
authors.forename: Rami
authors.initials: R
authors.lastname: Kotb
mesh_terms: D005260:Female; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000188:drug therapy*; D008875:Middle Aged; D017713:Platelet Transfusion; D011961:Receptors, Fc / Q000627:therapeutic use*; D053628:Receptors, Thrombopoietin / Q000819:agonists*; D011993:Recombinant Fusion Proteins / Q000627:therapeutic use*; D013921:Thrombocytopenia / Q000188:drug therapy*; D013926:Thrombopoietin / Q000627:therapeutic use*
chemical_list: D011961:Receptors, Fc; D053628:Receptors, Thrombopoietin; D011993:Recombinant Fusion Proteins; D013926:Thrombopoietin; C488777:romiplostim