title: Perceived burden in adherence of antiretroviral treatment in rural China.
abstract: To determine the level of antiretroviral treatment adherence and explore the correlated factors of perceived burden of taking antiretroviral medications among people living with HIV (PLH) in a rural area of China. Data were collected from 66 PLH who were currently receiving antiretroviral treatment. Face-to-face interviews were conducted during August to October, 2009. Approximately 18.2% of participants failed to adhere to antiretroviral treatment in the previous 30 days. A majority of PLH reported that taking antiretroviral medications posed a burden to them. Those who perceived a higher level of burden were more likely to be women, to have lower annual income, and to report a high level of depressive symptoms, poor physical health, and strained family interactions. Findings suggest that future programs in promoting adherence to antiretroviral treatment should address issues related to psychosocial well-being and PLH's interactions with their family members.
authors.affiliation: Semel Institute for Neuroscience and Human Behavior, Center for Community Health, University of California at Los Angeles, USA. lililili@ucla.edu
authors.forename: Li
authors.initials: L
authors.lastname: Li
authors.forename: Guoping
authors.initials: G
authors.lastname: Ji
authors.forename: Yingying
authors.initials: Y
authors.lastname: Ding
authors.forename: Junru
authors.initials: J
authors.lastname: Tian
authors.forename: Alex
authors.initials: A
authors.lastname: Lee
mesh_terms: D000328:Adult; D044966:Anti-Retroviral Agents / Q000191:economics / Q000627:therapeutic use; D001294:Attitude to Health; D002681:China / Q000453:epidemiology; D017281:Cost of Illness; D003863:Depression / Q000209:etiology; D064420:Drug-Related Side Effects and Adverse Reactions / Q000523:psychology; D054541:Family Conflict; D005260:Female; D015658:HIV Infections / Q000188:drug therapy / Q000191:economics / Q000453:epidemiology / Q000523:psychology; D006801:Humans; D008297:Male; D055118:Medication Adherence / Q000523:psychology; D008875:Middle Aged; D010817:Physician-Patient Relations; D010865:Pilot Projects; D012307:Risk Factors; D019035:Rural Health Services / Q000706:statistics & numerical data; D012944:Social Support; D016896:Treatment Outcome; D016903:Drug Monitoring
chemical_list: D044966:Anti-Retroviral Agents
references.citation: Lancet. 2007 Feb 24;369(9562):679-90
references.pmid: 17321313
references.citation: Clin Infect Dis. 1999 Oct;29(4):824-30
references.pmid: 10589897
references.citation: Ann Intern Med. 2009 Aug 18;151(4):241-51, W-52
references.pmid: 19687491
references.citation: AIDS. 2006 Feb 28;20(4):585-91
references.pmid: 16470123
references.citation: AIDS. 2007 Dec;21 Suppl 8:S149-55
references.pmid: 18172384
references.citation: Ann Intern Med. 2001 May 15;134(10):968-77
references.pmid: 11352698
references.citation: Clin Infect Dis. 2003 Oct 15;37(8):1112-8
references.pmid: 14523777
references.citation: Fam Process. 1994 Jun;33(2):203-16
references.pmid: 7925929
references.citation: AIDS Res Ther. 2009 Apr 28;6:7
references.pmid: 19400929
references.citation: Qual Life Res. 1997 Aug;6(6):481-93
references.pmid: 9330549
references.citation: Qual Life Res. 2004 Apr;13(3):587-99
references.pmid: 15130023
references.citation: Fam Process. 1985 Jun;24(2):225-39
references.pmid: 4018243
references.citation: AIDS. 2007 Dec;21 Suppl 8:S143-8
references.pmid: 18172383
references.citation: AIDS Care. 1996 Jun;8(3):261-9
references.pmid: 8827119
references.citation: J Acquir Immune Defic Syndr. 2002 Dec 15;31 Suppl 3:S136-9
references.pmid: 12562037
references.citation: Arch Gen Psychiatry. 1965 Jan;12:63-70
references.pmid: 14221692
references.citation: J Assoc Nurses AIDS Care. 2003 Jul-Aug;14(4):61-9
references.pmid: 12953613
references.citation: AIDS Patient Care STDS. 2005 Aug;19(8):526-37
references.pmid: 16124847
references.citation: Nurs Health Sci. 2010 Jun;12(2):212-20
references.pmid: 20602694
references.citation: AIDS Patient Care STDS. 2008 Jan;22(1):71-80
references.pmid: 18095837
references.citation: AIDS Behav. 2010 Apr;14(2):289-99
references.pmid: 18648925
references.citation: Qual Life Res. 2004 Apr;13(3):601-10
references.pmid: 15130024
references.citation: Cell Res. 2005 Nov-Dec;15(11-12):877-82
references.pmid: 16354563
references.citation: AIDS Care. 2005 Jan;17(1):10-22
references.pmid: 15832830
references.citation: Ann Intern Med. 2000 Jul 4;133(1):21-30
references.pmid: 10877736
references.citation: Res Aging. 2010 Jan 1;32(1):19-39
references.pmid: 20221313
references.citation: AIDS Patient Care STDS. 1999 Mar;13(3):185-97
references.pmid: 10375267
references.citation: Int J Epidemiol. 2010 Aug;39(4):973-9
references.pmid: 19556327
references.citation: Top HIV Med. 2003 Nov-Dec;11(6):185-98
references.pmid: 14724327
references.citation: J Gen Intern Med. 2003 Apr;18(4):248-57
references.pmid: 12709091
references.citation: Health Policy Plan. 2001 Mar;16(1):41-6
references.pmid: 11238429
references.citation: AIDS Behav. 2006 Sep;10(5):509-17
references.pmid: 16741672
references.citation: JAMA. 2006 Aug 9;296(6):679-90
references.pmid: 16896111