title: MINT, the molecular interaction database: 2012 update.
abstract: The Molecular INTeraction Database (MINT, http://mint.bio.uniroma2.it/mint/) is a public repository for protein-protein interactions (PPI) reported in peer-reviewed journals. The database grows steadily over the years and at September 2011 contains approximately 235,000 binary interactions captured from over 4750 publications. The web interface allows the users to search, visualize and download interactions data. MINT is one of the members of the International Molecular Exchange consortium (IMEx) and adopts the Molecular Interaction Ontology of the Proteomics Standard Initiative (PSI-MI) standards for curation and data exchange. MINT data are freely accessible and downloadable at http://mint.bio.uniroma2.it/mint/download.do. We report here the growth of the database, the major changes in curation policy and a new algorithm to assign a confidence to each interaction.
authors.affiliation: Department of Biology, University of Rome Tor Vergata, Via della Ricerca Scientifica, 00133 Rome, Italy.
authors.forename: Luana
authors.initials: L
authors.lastname: Licata
authors.forename: Leonardo
authors.initials: L
authors.lastname: Briganti
authors.forename: Daniele
authors.initials: D
authors.lastname: Peluso
authors.forename: Livia
authors.initials: L
authors.lastname: Perfetto
authors.forename: Marta
authors.initials: M
authors.lastname: Iannuccelli
authors.forename: Eugenia
authors.initials: E
authors.lastname: Galeota
authors.forename: Francesca
authors.initials: F
authors.lastname: Sacco
authors.forename: Anita
authors.initials: A
authors.lastname: Palma
authors.forename: Aurelio Pio
authors.initials: AP
authors.lastname: Nardozza
authors.forename: Elena
authors.initials: E
authors.lastname: Santonico
authors.forename: Luisa
authors.initials: L
authors.lastname: Castagnoli
authors.forename: Gianni
authors.initials: G
authors.lastname: Cesareni
mesh_terms: D000465:Algorithms; D000818:Animals; D030562:Databases, Protein; D006801:Humans; D051379:Mice; D025941:Protein Interaction Mapping; D011506:Proteins / Q000737:chemistry / Q000235:genetics; D051381:Rats
chemical_list: D011506:Proteins
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