title: Targeted immunosuppression: no longer naïve.
authors.forename: Robert S
authors.initials: RS
authors.lastname: Hagan
authors.forename: Jonathan D
authors.initials: JD
authors.lastname: Powell
mesh_terms: D000818:Animals; D001169:Arthritis, Experimental / Q000628:therapy*; D049109:Cell Proliferation / Q000187:drug effects*; D005260:Female; D006801:Humans; D020935:MAP Kinase Signaling System; D006377:T-Lymphocytes, Helper-Inducer; D058570:TOR Serine-Threonine Kinases
chemical_list: C546843:mTOR protein, mouse; D058570:TOR Serine-Threonine Kinases
references.citation: Nature. 2009 Jul 2;460(7251):108-12
references.pmid: 19543266
references.citation: Immunity. 2011 Apr 22;34(4):541-53
references.pmid: 21511183
references.citation: Science. 2011 Jun 10;332(6035):1317-22
references.pmid: 21659604
references.citation: Curr Med Chem. 2011;18(20):2995-3014
references.pmid: 21651476
references.citation: Nat Rev Mol Cell Biol. 2009 May;10(5):307-18
references.pmid: 19339977
references.citation: Sci Signal. 2011 Mar 29;4(166):pe16
references.pmid: 21447797
references.citation: Science. 2011 Jun 10;332(6035):1322-6
references.pmid: 21659605
references.citation: Curr Opin Immunol. 2004 Jun;16(3):314-20
references.pmid: 15134780
references.citation: Curr Opin Cell Biol. 2011 Dec;23(6):707-15
references.pmid: 21925855
references.citation: Front Biosci. 2008 May 01;13:4258-75
references.pmid: 18508509
references.citation: Immunity. 2009 Jun 19;30(6):832-44
references.pmid: 19538929
references.citation: Clin Immunol. 2012 Feb;142(2):127-38
references.pmid: 22075384
references.citation: Nat Immunol. 2011 Apr;12(4):295-303
references.pmid: 21358638
references.citation: Sci Signal. 2009 Apr 21;2(67):pe24
references.pmid: 19383975
references.citation: Clin Cancer Res. 2010 Mar 15;16(6):1924-37
references.pmid: 20215549