title: Visual gravitational vertical perception in peripheral vestibular hypofunction.
abstract: CONCLUSIONS
  Rise time in the estimation of the gravitational vertical in the head tilt response (HTR) test is increased in patients with peripheral vestibular lesions and residual chronic dizziness.
  
  
  OBJECTIVE
  Assessment of the perception of the gravitational vertical in patients with peripheral vestibular lesions through the HTR.
  
  
  METHODS
  HTR was studied in 12 patients with peripheral vestibular lesion, 8 clinically with chronic dizziness and 4 without it; 23 normal subjects were studied as control group. Two parameters of the HTR were assessed, rise time and steady-state error to characterize a dynamical system step response. The Kolmogorov-Smirnov test (alpha = 5%) was used to verify normal distribution (steady-state error, p = 0.53; rise time, p = 0.88). The three sigma ellipse was calculated for the control group. ROC curves were used to measure the sensitivity and specificity of these parameters.
  
  
  RESULTS
  Rise time showed increased values in peripheral vestibular lesion patients with chronic dizziness. Two-dimensional analysis (rise time vs steady-state error) allows a better discrimination between patients with peripheral vestibular hypofunction with chronic dizziness and the rest of the studied population.
authors.affiliation: Biomedical Engineering Program, Laboratory of Otoneurology, British Hospital, Montevideo, Uruguay. hsuarez@chasque.net
authors.forename: Hamlet
authors.initials: H
authors.lastname: Suárez
authors.forename: Darío
authors.initials: D
authors.lastname: Geisinger
authors.forename: Enrique
authors.initials: E
authors.lastname: Ferreira
authors.forename: Alejo
authors.initials: A
authors.lastname: Suárez
authors.forename: Cecilia San
authors.initials: CS
authors.lastname: Román
authors.forename: Gonzalo
authors.initials: G
authors.lastname: Sotta
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D004244:Dizziness / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008297:Male; D008575:Meniere Disease / Q000503:physiopathology*; D008875:Middle Aged; D020338:Vestibular Neuronitis / Q000503:physiopathology*; D014796:Visual Perception / Q000502:physiology*; D055815:Young Adult