title: Depression is associated with sarcopenia, not central obesity, in elderly korean men.
abstract: OBJECTIVE
  To examine the relationship between depression and various components of body composition, including fat and muscle, in elderly Koreans.
  
  
  METHODS
  A cross-sectional sample of a longitudinal cohort from the Ansan Geriatric (AGE) Study.
  
  
  METHODS
  Elderly people living in urban area (Ansan City, South Korea).
  
  
  METHODS
  Eight hundred thirty-six participants (378 male, 458 female) aged 60 and older were recruited from April 2006 to January 2008.
  
  
  METHODS
  Depressive symptoms were examined using the Korean version of the 30-item Geriatric Depression Scale (KGDS). Participants taking antidepressant medications or with a KGDS score of 14 or greater were classified as having depression. Abdominal visceral fat area (VFA) and subcutaneous fat area were assessed using single-slice computed tomography, and appendicular skeletal muscle mass (ASM) and percentage body fat (%BF) were determined using whole-body dual-energy X-ray absorptiometry.
  
  
  RESULTS
  Elderly men with depression had a lower ASM than those without depression (P = .01) after adjusting for age, body weight, and height. In men, the risk of depression was lower with higher body mass index (BMI) (odds ratio (OR) per 1-standard deviation (SD) increase = 0.70, 95% confidence interval (CI) = 0.51-0.96) after adjusting for all confounding variables and higher ASM (OR per 1-SD increase = 0.49; 95% CI = 0.29-0.85) after controlling for age, height, and weight. Similarly, depression was negatively associated with BMI in women (OR per 1-SD increase = 0.73; 95% CI = 0.56-0.95). Waist circumference, %BF, and VFA were not consistently associated with depression in men or women.
  
  
  CONCLUSIONS
  Depression in elderly Koreans is associated with low body mass and sarcopenia, especially in men.
authors.affiliation: Departments of Internal Medicine, Korea University, Gyunggi-do, Korea.
authors.forename: Nam Hoon
authors.initials: NH
authors.lastname: Kim
authors.forename: Hye Sook
authors.initials: HS
authors.lastname: Kim
authors.forename: Chai Ryoung
authors.initials: CR
authors.lastname: Eun
authors.forename: Ji A
authors.initials: JA
authors.lastname: Seo
authors.forename: Hyun Joo
authors.initials: HJ
authors.lastname: Cho
authors.forename: Sin Gon
authors.initials: SG
authors.lastname: Kim
authors.forename: Kyung Mook
authors.initials: KM
authors.lastname: Choi
authors.forename: Sei Hyun
authors.initials: SH
authors.lastname: Baik
authors.forename: Dong Seop
authors.initials: DS
authors.lastname: Choi
authors.forename: Moon Ho
authors.initials: MH
authors.lastname: Park
authors.forename: Changsu
authors.initials: C
authors.lastname: Han
authors.forename: Nan Hee
authors.initials: NH
authors.lastname: Kim
mesh_terms: D015502:Absorptiometry, Photon; D000368:Aged; D015992:Body Mass Index; D003430:Cross-Sectional Studies; D003863:Depression / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology*; D005260:Female; D005500:Follow-Up Studies; D006304:Health Status; D006801:Humans; D015994:Incidence; D050152:Intra-Abdominal Fat; D008297:Male; D056128:Obesity, Abdominal / Q000453:epidemiology; D015995:Prevalence; D056910:Republic of Korea / Q000453:epidemiology; D012189:Retrospective Studies; D012307:Risk Factors; D055948:Sarcopenia / Q000150:complications* / Q000175:diagnosis / Q000453:epidemiology; D012737:Sex Factors