title: Living Donor Liver Transplantation for Caroli's Disease: A Report of Two Cases.
abstract: Caroli's disease (CD) is a rare autosomal recessive disorder characterized by intrahepatic cystic dilatation of the bile ducts. Patients with bilobar or progressive disease may require orthotopic liver transplantation (OLT). In the MELD era, living donor liver transplantation (LDLT) raised as the ultimate treatment option for these patients, once their MELD score is usually low. Herein, we describe 2 cases of patients (a 2-year-old girl and a 19-year-old teenager) that successfully underwent LDLT as a treatment for diffuse CD. The good postoperative courses of the two cases indicate that LDLT is a feasible option in the treatment of this disorder, even in complicated or early age patients.
authors.affiliation: Liver Transplantation Unit, Bonsucesso Federal Hospital, Health Ministry, Rio de Janeiro, 21041-030, RJ, Brazil.
authors.forename: Klaus
authors.initials: K
authors.lastname: Steinbrück
authors.forename: Marcelo
authors.initials: M
authors.lastname: Enne
authors.forename: Reinaldo
authors.initials: R
authors.lastname: Fernandes
authors.forename: Jose M
authors.initials: JM
authors.lastname: Martinho
authors.forename: Lúcio F
authors.initials: LF
authors.lastname: Pacheco-Moreira
references.citation: J Hepatobiliary Pancreat Surg. 2001;8(3):284-6
references.pmid: 11455493
references.citation: Hepatogastroenterology. 2005 Mar-Apr;52(62):606-9
references.pmid: 15816487
references.citation: Br Med J. 1906 Feb 24;1(2356):434-6
references.pmid: 20762542
references.citation: Transplant Proc. 2008 Nov;40(9):3121-2
references.pmid: 19010212
references.citation: HPB Surg. 1993 Aug;7(1):81-6; discussion 86-7
references.pmid: 8260439
references.citation: Intensive Care Med. 1999 Sep;25(9):1017-20
references.pmid: 10501763
references.citation: Transpl Int. 1997;10(3):241-4
references.pmid: 9163868
references.citation: Hepatobiliary Pancreat Dis Int. 2008 Feb;7(1):97-100
references.pmid: 18234647
references.citation: Chin Med J (Engl). 2007 Aug 20;120(16):1404-7
references.pmid: 17825168
references.citation: Eur J Gastroenterol Hepatol. 1998 Feb;10(2):105-8
references.pmid: 9581983
references.citation: Am J Surg. 1983 Jan;145(1):41-8
references.pmid: 6295196
references.citation: Sem Hop. 1958 Feb 18;34(8/2):488-95/SP
references.pmid: 13543375
references.citation: Ann Surg. 2007 Aug;246(2):236-45
references.pmid: 17667502
references.citation: Surgery. 2005 Nov;138(5):888-98
references.pmid: 16291390
references.citation: Rev Esp Enferm Dig. 2008 Feb;100(2):71-5
references.pmid: 18366263
references.citation: Pediatr Transplant. 2008 Jun;12(4):483-6
references.pmid: 18179642
references.citation: Liver Transpl. 2006 Mar;12(3):416-21
references.pmid: 16498655
references.citation: Transplant Proc. 2005 Sep;37(7):3133-6
references.pmid: 16213328
references.citation: Transpl Int. 2006 May;19(5):381-8
references.pmid: 16623873
references.citation: Nephrol Dial Transplant. 2002 Jun;17(6):1113-5
references.pmid: 12032206
references.citation: Liver Transpl. 2008 Jan;14(1):11-7
references.pmid: 18161799
references.citation: Am J Surg. 1977 Aug;134(2):263-9
references.pmid: 889044
references.citation: Hepatogastroenterology. 1995 Apr;42(2):175-81
references.pmid: 7672768
references.citation: Hepatogastroenterology. 2001 May-Jun;48(39):672-4
references.pmid: 11462899
references.citation: Ann Surg. 2008 Feb;247(2):357-64
references.pmid: 18216545
references.citation: Am J Gastroenterol. 1997 Oct;92(10):1938-40
references.pmid: 9382076
references.citation: J Am Coll Surg. 2006 Jun;202(6):928-32
references.pmid: 16735207
references.citation: World J Surg. 2002 Apr;26(4):462-9
references.pmid: 11910481