title: Zinc-replacement therapy may not reduce oral pain in patients with zinc-deficient burning mouth syndrome (BMS).
abstract: BACKGROUND
  Zinc deficiency may be a cause of burning mouth syndrome as zinc replacement therapy has therapeutic effects. Cho GS, Han MW, Lee B, Roh J, Choi S, Cho K, et al. J Oral Pathol Med 2010;39(9):722-7.
  
  
  METHODS
  Vinodh Bhoopathi, BDS, MPH, DScD, Ana Karina Mascarenhas, BDS, MPH, DrPH PURPOSE/QUESTION: In patients with BMS and low serum zinc levels, does zinc-replacement therapy reduce pain? Authors using an animal model also attempted to demonstrate a causal relationship between BMS and zinc deficiency
  
  
  BACKGROUND
  Information not available
  
  
  METHODS
  Randomized controlled trial
  
  
  METHODS
  Level 2: Limited-quality, patient-oriented evidence
  
  
  METHODS
  Not applicable.
authors.affiliation: Nova Southeastern University College of Dental Medicine, Fort Lauderdale, FL 33328, USA. Vinodh.Bhoopathi@nova.edu
authors.forename: Vinodh
authors.initials: V
authors.lastname: Bhoopathi
authors.forename: Ana Karina
authors.initials: AK
authors.lastname: Mascarenhas