title: Liver transplantation for refractory severe pruritus related to widespread multifocal hepatic focal nodular hyperplasia (FNH) in a child: case report and review of literature.
abstract: FNH is a rare and benign tumor of the liver. It is not a conventional indication for liver transplantation, and no transplant for FNH in a child has been reported to date. Multifocal FNH growing in adolescent age to a widespread tumor invading the whole liver and associated with severe refractory pruritus was an unusual indication for transplantation in a 13-yr-old girl. The operation and the follow-up were uneventful, allowing full recovery and disappearance of pruritus.
authors.affiliation: Transplantation Center, Ospedale Pediatrico Bambino Gesù, Roma, Italy.
authors.forename: L
authors.initials: L
authors.lastname: Merli
authors.forename: C
authors.initials: C
authors.lastname: Grimaldi
authors.forename: L
authors.initials: L
authors.lastname: Monti
authors.forename: V
authors.initials: V
authors.lastname: Nobili
authors.forename: P
authors.initials: P
authors.lastname: Francalanci
authors.forename: J
authors.initials: J
authors.lastname: de Ville de Goyet
mesh_terms: D000293:Adolescent; D002648:Child; D005260:Female; D020518:Focal Nodular Hyperplasia / Q000150:complications* / Q000628:therapy*; D006801:Humans; D008099:Liver / Q000002:abnormalities / Q000473:pathology; D016031:Liver Transplantation / Q000379:methods*; D011537:Pruritus / Q000628:therapy*; D014057:Tomography, X-Ray Computed / Q000379:methods; D016896:Treatment Outcome