title: Levetiracetam-induced interstitial nephritis in a patient with glioma.
abstract: A 45-year-old man with a new diagnosis of low grade glioma was started on an escalating dose of levetiracetam (Lev) for seizure management. He gradually developed intractable nausea/vomiting and a high creatinine concentration due to acute renal failure which was attributed to Lev-induced interstitial nephritis. The medication was changed and his renal function rapidly improved to his baseline.
authors.affiliation: Department of Neurosciences, Moores Cancer Center, University of California San Diego, 3855 Suite 3336, Health Sciences Drive, La Jolla, California 92093-0819, USA.
authors.forename: Ali
authors.initials: A
authors.lastname: Mahta
authors.forename: Ryan Y
authors.initials: RY
authors.lastname: Kim
authors.forename: Santosh
authors.initials: S
authors.lastname: Kesari
mesh_terms: D058186:Acute Kidney Injury / Q000139:chemically induced* / Q000175:diagnosis; D000927:Anticonvulsants / Q000008:administration & dosage / Q000009:adverse effects*; D001254:Astrocytoma / Q000150:complications / Q000175:diagnosis / Q000473:pathology; D001932:Brain Neoplasms / Q000150:complications / Q000175:diagnosis / Q000473:pathology; D006801:Humans; D000077287:Levetiracetam; D008297:Male; D008875:Middle Aged; D009395:Nephritis, Interstitial / Q000139:chemically induced* / Q000175:diagnosis; D010889:Piracetam / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives*; D012640:Seizures / Q000188:drug therapy* / Q000209:etiology / Q000517:prevention & control
chemical_list: D000927:Anticonvulsants; D000077287:Levetiracetam; D010889:Piracetam