title: Differences between South Asians and White Europeans in five year outcome following percutaneous coronary intervention.
abstract: OBJECTIVE
  The aim of this study was to compare rates of target lesion revascularisation (TLR) and total mortality between South Asians (SAs) and White Europeans (WEs) following percutaneous coronary intervention (PCI).
  
  
  METHODS
  We followed a cohort of 293 SAs and 865 WEs patients admitted for elective or urgent PCI to de novo lesions. For each patient, baseline cardiovascular risk factors and angiographic data were obtained. Patients had long-term follow-up for all-cause mortality and TLR.
  
  
  RESULTS
  Patients were followed up over a median period of 54 months (inter-quartile range: 47-65). SAs were younger (62 ± 12 years vs. 66 ± 11 years; p < 0.0001), with a higher prevalence of diabetes, greater social deprivation [Carstairs score: 10.2 (IQR 6.5-12.1) vs. 3.3 (IQR 0.9-6.5); p < 0.0001] and presented more acutely (urgent PCI procedure). During the follow-up period, a total of 119 deaths and 111 TLR [94 repeat PCI and 17 coronary artery bypass grafting (CABG)] occurred. There was no significant difference in the rate of long-term all-cause mortality between SA and WE [31 (10.6%) vs. 107 (12.4%); OR: 0.84 (0.55-1.28); p = 0.47]. However, SA ethnicity was an independent predictor of long-term TLR, after adjusting for baseline clinical and procedural characteristics [54 (18.4%) vs. 57 (6.6%); OR: 2.83 (1.87-4.29); p < 0.0001].
  
  
  CONCLUSIONS
  South Asian patients were more likely to require re-admission to treat clinical restenosis of the index lesion. There was no significant long-term difference in all-cause mortality between SA and WE patients.
authors.affiliation: Department of Cardiology, City Hospital, Birmingham, UK.
authors.forename: I S
authors.initials: IS
authors.lastname: Toor
authors.forename: R
authors.initials: R
authors.lastname: Jaumdally
authors.forename: G Y H
authors.initials: GY
authors.lastname: Lip
authors.forename: D
authors.initials: D
authors.lastname: Pagano
authors.forename: W
authors.initials: W
authors.lastname: Dimitri
authors.forename: T
authors.initials: T
authors.lastname: Millane
authors.forename: C
authors.initials: C
authors.lastname: Varma
mesh_terms: D000368:Aged; D015906:Angioplasty, Balloon, Coronary / Q000401:mortality / Q000706:statistics & numerical data; D001210:Asia, Southeastern / Q000208:ethnology; D044466:Asian People / Q000208:ethnology*; D001026:Coronary Artery Bypass / Q000401:mortality / Q000706:statistics & numerical data; D003324:Coronary Artery Disease / Q000208:ethnology* / Q000628:therapy; D004739:England / Q000453:epidemiology; D005260:Female; D006801:Humans; D053208:Kaplan-Meier Estimate; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000208:ethnology* / Q000401:mortality / Q000628:therapy; D009204:Myocardial Revascularization; D015607:Stents; D016896:Treatment Outcome; D044465:White People / Q000208:ethnology*