title: GenomeView: a next-generation genome browser.
abstract: Due to ongoing advances in sequencing technologies, billions of nucleotide sequences are now produced on a daily basis. A major challenge is to visualize these data for further downstream analysis. To this end, we present GenomeView, a stand-alone genome browser specifically designed to visualize and manipulate a multitude of genomics data. GenomeView enables users to dynamically browse high volumes of aligned short-read data, with dynamic navigation and semantic zooming, from the whole genome level to the single nucleotide. At the same time, the tool enables visualization of whole genome alignments of dozens of genomes relative to a reference sequence. GenomeView is unique in its capability to interactively handle huge data sets consisting of tens of aligned genomes, thousands of annotation features and millions of mapped short reads both as viewer and editor. GenomeView is freely available as an open source software package.
authors.affiliation: Department of Plant Systems Biology, VIB, Technologiepark 927, 9052 Gent, Belgium. thomas@abeel.be
authors.forename: Thomas
authors.initials: T
authors.lastname: Abeel
authors.forename: Thomas
authors.initials: T
authors.lastname: Van Parys
authors.forename: Yvan
authors.initials: Y
authors.lastname: Saeys
authors.forename: James
authors.initials: J
authors.lastname: Galagan
authors.forename: Yves
authors.initials: Y
authors.lastname: Van de Peer
mesh_terms: D023281:Genomics / Q000379:methods*; D059014:High-Throughput Nucleotide Sequencing; D058977:Molecular Sequence Annotation; D016415:Sequence Alignment / Q000379:methods*; D017422:Sequence Analysis, DNA; D017423:Sequence Analysis, RNA; D012984:Software; D018511:Systems Integration; D014584:User-Computer Interface
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