title: Skin tissue engineering--in vivo and in vitro applications.
abstract: Significant progress has been made over the years in the development of in vitro-engineered substitutes that mimic human skin, either to be used as grafts for the replacement of lost skin or for the establishment of human-based in vitro skin models. This review summarizes these advances in in vivo and in vitro applications of tissue-engineered skin. We further highlight novel efforts in the design of complex disease-in-a-dish models for studies ranging from disease etiology to drug development and screening.
authors.affiliation: Department of Cell and Tissue Engineering, Fraunhofer-Institute for Interfacial Engineering and Biotechnology (IGB), Nobelstrasse 12, 70569 Stuttgart, Germany.
authors.forename: Florian
authors.initials: F
authors.lastname: Groeber
authors.forename: Monika
authors.initials: M
authors.lastname: Holeiter
authors.forename: Martina
authors.initials: M
authors.lastname: Hampel
authors.forename: Svenja
authors.initials: S
authors.lastname: Hinderer
authors.forename: Katja
authors.initials: K
authors.lastname: Schenke-Layland