title: [Preparation of natural matrix standard sample of minced eel for quality control of flumequine residue].
abstract: In order to obtain quality control samples for the analysis of flumequine residue in eel which are consistent with real detection samples, minced eel was prepared as natural matrix standard samples containing flumequine. The results showed that through the administration of drug application and appropriate time of sample acquisition, the natural positive matrix containing the expected levels (5-10 microg/kg) of flumequine and the representative of actual samples at the original state could be obtained. The uniformity of the material was ensured by homogenizing and paddle type blending. The irradiation of Co60-gamma rays at 12 kGy and the packaging material could prevent the degradation of the minced samples at ambient temperature and facilitate the inter-laboratory transfer in any season.
authors.affiliation: Fujian Entry-Exit Inspection and Quarantine Bureau, State Key Testing Laboratory of Eel and Food Origin Microorganism, Fujian Key Laboratory of Inspection and Quarantine Technology Research, Fuzhou 350001, China. ykjciq@163.com
authors.forename: Kongjie
authors.initials: K
authors.lastname: Yu
authors.forename: Fang
authors.initials: F
authors.lastname: Yang
authors.forename: Zhengcai
authors.initials: Z
authors.lastname: Liu
authors.forename: Jie
authors.initials: J
authors.lastname: Huang
authors.forename: Yaoping
authors.initials: Y
authors.lastname: Li
authors.forename: Zhihua
authors.initials: Z
authors.lastname: Chen
mesh_terms: D000818:Animals; D000890:Anti-Infective Agents / Q000032:analysis; D002853:Chromatography, Liquid / Q000379:methods; D004350:Drug Residues / Q000032:analysis* / Q000737:chemistry; D004524:Eels; D024841:Fluoroquinolones / Q000032:analysis*; D005506:Food Contamination / Q000032:analysis*; D011786:Quality Control; D012015:Reference Standards; D053719:Tandem Mass Spectrometry / Q000379:methods
chemical_list: D000890:Anti-Infective Agents; D024841:Fluoroquinolones; C012976:flumequine