title: Is there a role for physical activity in preventing cognitive decline in people with mild cognitive impairment?
abstract: Mild cognitive impairment (MCI) is a common clinical syndrome that identifies people at high risk of developing dementia. Although treatments for MCI are currently unavailable, preliminary evidence has identified potential neuro-protective effects of physical activity, which may lead to improved outcomes. However, there is uncertainty regarding the effectiveness, feasibility and acceptability of this treatment strategy. These uncertainties require further investigation before physical activity interventions can be recommended for routine care.
authors.affiliation: Academic Unit of Elderly Care and Rehabilitation, Bradford Institute for Health Research, Bradford, West Yorkshire BD9 6RJ, UK. sally.barber@bthft.nhs.uk
authors.forename: Sally E
authors.initials: SE
authors.lastname: Barber
authors.forename: Andrew P
authors.initials: AP
authors.lastname: Clegg
authors.forename: John B
authors.initials: JB
authors.lastname: Young
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D060825:Cognitive Dysfunction / Q000517:prevention & control / Q000628:therapy*; D003704:Dementia / Q000517:prevention & control / Q000628:therapy; D005260:Female; D006801:Humans; D008297:Male; D009043:Motor Activity; D016032:Randomized Controlled Trials as Topic