title: Subclinical Myocardial Dysfunction in Metabolic Syndrome Patients without Hypertension.
abstract: BACKGROUND
  The aim of this study was to evaluate myocardial function in patients with non-hypertensive metabolic syndrome.
  
  
  METHODS
  We selected metabolic syndrome patients (n = 42) without evidence of hypertension and compared them to age-matched control individuals (n = 20). All patients were evaluated by two-dimensional and tissue Doppler echocardiography including tissue Doppler derived strain and strain rate measurements.
  
  
  RESULTS
  There were no significant differences between the two groups in mitral E and A inflow velocities or the E/A ratio. However, systolic and early diastolic myocardial velocities, and strain rate were significantly lower in patients with metabolic syndrome than in the control group (all p < 0.05). Multiple stepwise regression analyses revealed that age, waist circumference, and systolic blood pressure were independently associated with peak systolic myocardial velocity.
  
  
  CONCLUSIONS
  These results indicate that metabolic syndrome patients without hypertension may have decrease of myocardial systolic and early diastolic velocities on tissue Doppler imaging, even if they appear to have normal systolic and diastolic function on conventional echocardiography.
authors.affiliation: Department of Cardiology, Dong-A University College of Medicine, Busan, Korea.
authors.forename: Jeong-Min
authors.initials: JM
authors.lastname: Seo
authors.forename: Tae-Ho
authors.initials: TH
authors.lastname: Park
authors.forename: Dong-Yeol
authors.initials: DY
authors.lastname: Lee
authors.forename: Young-Rak
authors.initials: YR
authors.lastname: Cho
authors.forename: Hee-Kyung
authors.initials: HK
authors.lastname: Baek
authors.forename: Jong-Seong
authors.initials: JS
authors.lastname: Park
authors.forename: Moo-Hyun
authors.initials: MH
authors.lastname: Kim
authors.forename: Young-Dae
authors.initials: YD
authors.lastname: Kim
authors.forename: Sun-Young
authors.initials: SY
authors.lastname: Choi
authors.forename: Sun-Mi
authors.initials: SM
authors.lastname: Lee
authors.forename: Young-Seoub
authors.initials: YS
authors.lastname: Hong
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