title: A novel polymorphism of the  myogenin gene is associated with body measurement traits in native Chinese breeds.
abstract: Using  PCR-SSCP and DNA sequencing technology, we examined the association of single  nucleotide polymorphisms (SNPs) in the bovine MyoG gene with body  measurement traits in 779 individuals of six native Chinese cattle breeds,  namely Luxi, Luxi × Simmental crossbred, Nanyang, Xia'nan, Jiaxian red, and  Qinchuan. A novel SNP, T314C, was detected. Allelic frequencies of MyoG-T/C  in the six breeds were 0.8308/0.1692, 0.8774/0.1226, 0.8021/0.1979,  0.8209/0.1791, 0.8630/0.1370, 0.8044/0.1956, respectively. Least squares  analysis revealed a significant (P < 0.05) association of the MyoG SNP  with rump length in four breeds (Luxi, Xia'nan, Jiaxian red, and Qinchuan),  with hucklebone width in three breeds (Luxi × Simmental crossbred, Nanyang and  Xia'nan), with waist height in two breeds (Luxi × Simmental crossbred and  Nanyang) and with body length in the Luxi breed. We conclude that the MyoG SNP  has potential as a genetic marker for economically relevant body measurement  traits in native Chinese cattle breeds.
authors.affiliation: College of Animal Science and Technology, Northwest Agriculture and Forestry University, Yangling, Shaanxi, PR China.
authors.forename: M
authors.initials: M
authors.lastname: Xue
authors.forename: L S
authors.initials: LS
authors.lastname: Zan
authors.forename: L
authors.initials: L
authors.lastname: Gao
authors.forename: H B
authors.initials: HB
authors.lastname: Wang
mesh_terms: D000818:Animals; D049628:Body Size / Q000235:genetics*; D001947:Breeding; D002417:Cattle / Q000235:genetics* / Q000254:growth & development; D002681:China; D005819:Genetic Markers; D018008:Myogenin / Q000235:genetics*; D018807:Polymorphism, Single-Stranded Conformational; D040641:Quantitative Trait Loci
chemical_list: D005819:Genetic Markers; D018008:Myogenin