title: 2-(4-Iodo-phen-yl)-1,2,3,4-tetra-hydro-isoquinoline-1-carbonitrile.
abstract: In the title compound, C(16)H(13)IN(2), the benzene ring of the tetra-hydro-isoquinoline moiety makes a dihedral angle of 45.02 (9)° with the benzene ring of the 4-iodo-phenyl fragment. The N atom and the adjacent unsubstituted C atom of the tetra-hydro-isoquinoline unit are displaced by 0.294 (2) and 0.441 (3) Å, respectively, from the plane through the remaining eight C atoms. In the crystal, pairs of adjacent mol-ecules are linked into dimers by weak inter-molecular C-H⋯π inter-actions.
authors.forename: Yanni
authors.initials: Y
authors.lastname: Ma
authors.forename: Lili
authors.initials: L
authors.lastname: Du
authors.forename: Qi
authors.initials: Q
authors.lastname: Zhang
authors.forename: Fangjun
authors.initials: F
authors.lastname: Cao
authors.forename: Le
authors.initials: L
authors.lastname: Zhou
references.citation: Bioorg Med Chem. 2009 Feb 1;17(3):1207-13
references.pmid: 19147367
references.citation: Bioorg Med Chem Lett. 2006 Jun 15;16(12):3180-3
references.pmid: 16632360
references.citation: Biol Pharm Bull. 2005 Aug;28(8):1355-62
references.pmid: 16079473
references.citation: Biochem Pharmacol. 2002 Mar 1;63(5):909-20
references.pmid: 11911843
references.citation: Acta Crystallogr A. 2008 Jan;64(Pt 1):112-22
references.pmid: 18156677
references.citation: Chem Pharm Bull (Tokyo). 1985 Oct;33(10):4139-51
references.pmid: 4092262
references.citation: Eur J Med Chem. 2011 Feb;46(2):567-78
references.pmid: 21185109