title: Takotsubo cardiomyopathy due to iatrogenic methadone withdrawal.
abstract: Takotsubo cardiomyopathy is a syndrome characterized by transient apical ballooning         or reversible midventricular systolic dysfunction. Most cases occur in postmenopausal         women and are typically triggered by an acute medical illness or emotional or physical         stress. Its presentation is highly suggestive of myocardial ischemia, but there is little or         no evidence of epicardial coronary artery disease. To our knowledge there are only three         reported cases in the literature of Takotsubo cardiomyopathy induced by opioid agonist         withdrawal in adults; ours is the first reported case of iatrogenic methadone withdrawal         leading to Takotsubo cardiomyopathy.
authors.affiliation: Department of Medicine, Staten Island University Hospital, Staten Island, NY, USA.
authors.forename: Faisal B
authors.initials: FB
authors.lastname: Saiful
authors.forename: James
authors.initials: J
authors.lastname: Lafferty
authors.forename: Chin Hee
authors.initials: CH
authors.lastname: Jun
authors.forename: Sumaya
authors.initials: S
authors.lastname: Teli
authors.forename: Srinivas
authors.initials: S
authors.lastname: Duvvuri
authors.forename: Saakshi
authors.initials: S
authors.lastname: Khattri
authors.forename: Tariq
authors.initials: T
authors.lastname: Bhat
mesh_terms: D000701:Analgesics, Opioid / Q000008:administration & dosage / Q000506:poisoning*; D017023:Coronary Angiography; D062787:Drug Overdose; D004452:Echocardiography; D004562:Electrocardiography; D006801:Humans; D007049:Iatrogenic Disease; D008297:Male; D008691:Methadone / Q000008:administration & dosage / Q000506:poisoning*; D008875:Middle Aged; D009270:Naloxone / Q000008:administration & dosage / Q000009:adverse effects*; D009292:Narcotic Antagonists / Q000008:administration & dosage / Q000009:adverse effects*; D058850:Opiate Substitution Treatment; D009293:Opioid-Related Disorders / Q000534:rehabilitation*; D054549:Takotsubo Cardiomyopathy / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy
chemical_list: D000701:Analgesics, Opioid; D009292:Narcotic Antagonists; D009270:Naloxone; D008691:Methadone