title: No effects of Korean pine nut triacylglycerol on satiety and energy intake.
abstract: BACKGROUND
  Triacylglycerols (TAG) have been shown to have potential appetite suppressing effects. This study examined the effects of 3 g and 6 g Korean pine nut triacylglycerols (PinnoThin) on appetite and energy intake.
  
  
  METHODS
  130 g Isoenergetic yogurt containing either placebo (milk fat) or PinnoThin TAG was consumed as a breakfast, after an overnight fast, in a double blind randomized crossover design. Appetite profile ratings were determined by visual analogue scale at regular intervals for a period of 4 h after the breakfast. In phase I, 6 g PinnoThin TAG and placebo was tested in thirty-three healthy women (mean ± SD, BMI 26.4 ± 3.8 kg/m2; age 28 ± 10 y) to determine the appetite suppressing effect in time. In phase II, an additional dose of 3 g PinnoThin TAG, as well as 6 g PinnoThin TAG and placebo, was tested in thirty-four women (BMI 25.8 ± 2.9 kg/m2; age 25 ± 9 y) to determine energy intake from an ad libitum lunch offered at 210 min after the breakfast, at which maximal differences in appetite profile ratings were present in phase I.
  
  
  RESULTS
  Area under the curve of appetite profile ratings was not significantly different between the conditions. Energy intake was 9.5% lower after 6 g PinnoThin TAG compared with 3 g PinnoThin TAG, but there was no significant difference with the placebo.
  
  
  CONCLUSIONS
  A dosage of 6 g PinnoThin TAG is not sufficient to suppress appetite and energy intake.
  
  
  BACKGROUND
  Clinical Trials NCT01034605.
authors.affiliation: Maastricht University, Department of Human Biology, Nutrition and Toxicology Research Institute Maastricht, 6200 MD, Maastricht, The Netherlands. s.verhoef@maastrichtuniversity.nl.
authors.forename: Sanne Pm
authors.initials: SP
authors.lastname: Verhoef
authors.forename: Klaas R
authors.initials: KR
authors.lastname: Westerterp
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