title: Immunochemical studies of Salmonella Dakar and Salmonella Telaviv O-antigens (serogroup O:28).
abstract: Salmonella Dakar and Salmonella Telaviv bacteria belong to serogroup O:28, which represents 107 serovars and possesses only the epitope O28. Salmonella Telaviv has the subfactors O28(1) and O28(2) , whereas S. Dakar has O28(1) and O28(3) . So far, only limited serological and immunological information for this serogroup is available in the literature. Knowledge of the structures of their O-polysaccharides and the immunochemical investigations performed in this work allowed to reveal the nature of subfactor O28(1) as attributed to the presence of 3-linked (or 3,4-disubstituted) α-d-GalpNAc in the main chains of S. Dakar and S. Telaviv O-polysaccharides. An explanation for the cross-reactions between Salmonella enterica O28 O-antigens and other Salmonella O-polysaccharides and their structural similarity to Escherichia coli O-serogroups is also given.
authors.affiliation: Department of Molecular Microbiology and Serology, National Salmonella Centre, Medical University of Gdańsk, Gdańsk, Poland.
authors.forename: Halina
authors.initials: H
authors.lastname: Dziadziuszko
authors.forename: Jolanta
authors.initials: J
authors.lastname: Kumirska
authors.forename: Sylwia
authors.initials: S
authors.lastname: Muża
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Czerwicka
authors.forename: Emilia A
authors.initials: EA
authors.lastname: Lubecka
authors.forename: Piotr
authors.initials: P
authors.lastname: Stepnowski
authors.forename: Danuta
authors.initials: D
authors.lastname: Kunikowska
mesh_terms: D002240:Carbohydrate Sequence; D003429:Cross Reactions; D004926:Escherichia coli / Q000737:chemistry / Q000276:immunology; D019081:O Antigens / Q000737:chemistry / Q000276:immunology*; D011135:Polysaccharides, Bacterial / Q000737:chemistry / Q000276:immunology*; D019779:Salmonella enterica / Q000737:chemistry / Q000276:immunology*; D012703:Serotyping / Q000379:methods
chemical_list: D019081:O Antigens; D011135:Polysaccharides, Bacterial