title: Outcome after implantable cardioverter-defibrillator in patients with Brugada syndrome: the Gulf Brugada syndrome registry.
abstract: OBJECTIVE
  Among patients with Brugada syndrome (BS) and aborted cardiac arrest, syncope, or inducible ventricular fibrillation at electrophysiologic study (EPS), the only currently recommended therapy is an implantable cardioverter-defibrillator (ICD), but these are not without complications. We assessed the total number of shocks (appropriate and inappropriate) and complications related to ICD in patients with BS.
  
  
  RESULTS
  Twenty-five patients implanted with ICD for BS in 6 Gulf centers between January 1, 2002, and December 31, 2010, were reviewed. Implantable cardioverter-defibrillator indication was based on aborted cardiac arrest (24%), syncope (56%), or in asymptomatic patients with positive EPS (20%). During a follow-up of 41.2 ± 17.6 months, 3 patients (all with prior cardiac arrest) had appropriate device therapy. Four patients developed complications; 3 of them had inappropriate shocks.
  
  
  CONCLUSIONS
  In our cohort, appropriate device therapy was limited to cardiac arrest survivors, whereas none of those with syncope and/or positive EPS had arrhythmias. Overall complication rate was relatively high, including inappropriate ICD shocks.
authors.affiliation: Section of Adult Cardiology, Cardiovascular Department King Faisal Specialist Hospital and Research Center, Jeddah, Kingdom of Saudi Arabia. amindaoulah@yahoo.com
authors.forename: Amin
authors.initials: A
authors.lastname: Daoulah
authors.forename: Alawi A
authors.initials: AA
authors.lastname: Alsheikh-Ali
authors.forename: Ali H
authors.initials: AH
authors.lastname: Ocheltree
authors.forename: Sara
authors.initials: S
authors.lastname: Ocheltree
authors.forename: Salem
authors.initials: S
authors.lastname: Al-Kaabi
authors.forename: Majed
authors.initials: M
authors.lastname: Malik
authors.forename: Abdul-Karim
authors.initials: AK
authors.lastname: Al-Habib
authors.forename: Adel
authors.initials: A
authors.lastname: Hamed
authors.forename: Najib
authors.initials: N
authors.lastname: Al-Rawahi
authors.forename: Ali
authors.initials: A
authors.lastname: Al-Sayegh
authors.forename: Saad
authors.initials: S
authors.lastname: Al-Hasaniah
authors.forename: Eijaz
authors.initials: E
authors.lastname: Ul-Haq
mesh_terms: D000293:Adolescent; D000328:Adult; D053840:Brugada Syndrome / Q000175:diagnosis* / Q000517:prevention & control*; D017147:Defibrillators, Implantable; D006801:Humans; D019156:Indian Ocean; D008297:Male; D008875:Middle Aged; D012042:Registries; D016896:Treatment Outcome; D055815:Young Adult