title: [Management of acute alcoholic steatohepatitis].
abstract: Alcoholic steatohepatitis is an acute inflammatory liver disorder that often complicates the course of underlying cirrhosis. Severe alcoholic steatohepatitis, defined as a Maddrey's discriminant function greater than 32 or association with hepatic encephalopathy, carries a high short-term mortality that is significantly reduced by corticosteroids. A comprehensive work-up is necessary for the presence of concomitant infection or associated viral hepatitis. A liver biopsy must be performed to confirm the diagnosis prior to initiation of steroids. This article summarizes the management of alcoholic steatohepatitis.
authors.affiliation: Service de médecine interne générale, Département de médecine interne, de réhabilitation et de gériatrie, HUG, 1211 Genève 14. Fabienne.Groebli@hcuge.ch
authors.forename: Fabienne
authors.initials: F
authors.lastname: Groebli
authors.forename: Laurent
authors.initials: L
authors.lastname: Spahr
authors.forename: Nicolas
authors.initials: N
authors.lastname: Garin
mesh_terms: D005235:Fatty Liver, Alcoholic / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy*; D006801:Humans; D008099:Liver / Q000473:pathology; D012720:Severity of Illness Index