title: Polypyrrole nanoparticles: a potential optical coherence tomography contrast agent for cancer imaging.
abstract: A near-infrared (NIR) absorbing contrast agent based on polypyrrole nanoparticles is described. Quantitative optical coherence tomography studies on tissue phantoms and Mie scattering calculations indicate their potential application for early-stage cancer diagnosis.
authors.affiliation: Department of Chemistry, The University of Sheffield, Brook Hill, Yorkshire, UK.
authors.forename: Kin Man
authors.initials: KM
authors.lastname: Au
authors.forename: Zenghai
authors.initials: Z
authors.lastname: Lu
authors.forename: Stephen J
authors.initials: SJ
authors.lastname: Matcher
authors.forename: Steven P
authors.initials: SP
authors.lastname: Armes
mesh_terms: D003287:Contrast Media / Q000494:pharmacology*; D003952:Diagnostic Imaging / Q000379:methods*; D006801:Humans; D008495:Medical Oncology / Q000379:methods; D015233:Models, Statistical; D053758:Nanoparticles / Q000737:chemistry*; D009369:Neoplasms / Q000175:diagnosis*; D019047:Phantoms, Imaging; D011108:Polymers / Q000737:chemistry*; D011758:Pyrroles / Q000737:chemistry*; D012542:Scattering, Radiation; D013056:Spectrophotometry, Ultraviolet / Q000379:methods; D019265:Spectroscopy, Near-Infrared / Q000379:methods; D041623:Tomography, Optical Coherence / Q000379:methods*
chemical_list: D003287:Contrast Media; D011108:Polymers; D011758:Pyrroles; C067635:polypyrrole