title: An efficient route to tetrahydroindeno[2,1-b]pyrroles via a base-promoted reaction of (E)-2-alkynylphenylchalcone with 2-isocyanoacetate.
abstract: A base-promoted cascade reaction of (E)-2-alkynylphenylchalcone with 2-isocyanoacetate provides a novel and efficient route for the synthesis of tetrahydroindeno[2,1-b]pyrroles. The reaction proceeds smoothly in air under mild conditions with high efficiency.
authors.affiliation: Department of Chemistry, Fudan University, 220 Handan Road, Shanghai 200433, China.
authors.forename: Danqing
authors.initials: D
authors.lastname: Zheng
authors.forename: Shaoyu
authors.initials: S
authors.lastname: Li
authors.forename: Yong
authors.initials: Y
authors.lastname: Luo
authors.forename: Jie
authors.initials: J
authors.lastname: Wu
mesh_terms: D000085:Acetates / Q000737:chemistry*; D000388:Air; D000480:Alkynes / Q000737:chemistry*; D002384:Catalysis; D047188:Chalcones / Q000737:chemistry*; D020650:Combinatorial Chemistry Techniques; D006575:Heterocyclic Compounds, 3-Ring / Q000138:chemical synthesis* / Q000737:chemistry; D007192:Indenes / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D009570:Nitriles / Q000737:chemistry*; D011758:Pyrroles / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D000085:Acetates; D000480:Alkynes; D047188:Chalcones; D006575:Heterocyclic Compounds, 3-Ring; D007192:Indenes; D009570:Nitriles; D011758:Pyrroles