title: Valuable chemicals by the enzymatic modification of molecules of natural origin: terpenoids, steroids, phenolics and related compounds.
abstract: A renewed interest for using natural organic molecules for the production of valuable chemicals is observed in current organic processes. Natural compounds provide the access to natural grade chemicals when submitted to physical treatments or biotechnological processes. Dealing with structurally complex molecules, they can provide complex core structures for hemisynthesis purposes, and in many instances they offer the advantage of providing sustainable processes when using renewable resources. These assets could be synergistic with the assets of biocatalytic processes, to end-up with efficient and sustainable processes in the organic synthesis of valuable products. In this review, we have gathered a selection of examples on the use of enzymes for the modification of molecules of natural origin being either purified compounds (terpenoids, steroids, phenolics) or mixtures (essential oils, natural extracts) to access fine chemicals or organic polymers.
authors.affiliation: LCMBA UMR 6001 CNRS-Université de Nice-Sophia Antipolis, Institut de Chimie de Nice, Nice, France.
authors.forename: Anne-Laure
authors.initials: AL
authors.lastname: Groussin
authors.forename: Sylvain
authors.initials: S
authors.lastname: Antoniotti
mesh_terms: D002625:Chemistry, Organic / Q000379:methods*; D004798:Enzymes / Q000378:metabolism*; D010636:Phenols / Q000378:metabolism*; D013256:Steroids / Q000378:metabolism*; D013729:Terpenes / Q000378:metabolism*
chemical_list: D004798:Enzymes; D010636:Phenols; D013256:Steroids; D013729:Terpenes