title: Second-generation platelet concentrate (PRF) as a pulpotomy medicament in a permanent molar with pulpitis: a case report.
abstract: OBJECTIVE
  To discuss the clinical and radiographic success of a pulpotomy with second-generation platelet concentrate (PRF), in a human mature permanent molar tooth.
  
  
  CONCLUSIONS
  A 19-year-old female patient reported to the Department of Conservative Dentistry and Endodontics with established pulpitis in tooth 36. The tooth had a carious pulp exposure, with a history of lingering pain. After isolation, caries removal and pulp exposure, pulpotomy with PRF was performed and a permanent restoration was placed immediately. At the first recall (+1 day), no postoperative pain was reported. At 6, 12, 18 and 22 months recall, the tooth responded positively to pulp sensibility tests, and radiographic examination revealed a normal periodontal ligament space. Positive results of this case imply the need for more studies with larger sample sizes and a longer recall period to justify the use of this novel material for the treatment of pulpitis in human permanent molar teeth.
  
  
  CONCLUSIONS
  Pulpotomy with PRF could be an alternate treatment to mineral trioxide aggregate or other materials in mature permanent teeth with pulpitis.
authors.affiliation: Department of Conservative Dentistry, Rural Dental College, Loni, Ahmednagar, Maharastra, India.
authors.forename: H
authors.initials: H
authors.lastname: Hiremath
authors.forename: S
authors.initials: S
authors.lastname: Saikalyan
authors.forename: S S
authors.initials: SS
authors.lastname: Kulkarni
authors.forename: V
authors.initials: V
authors.lastname: Hiremath
mesh_terms: D017607:Aluminum Compounds / Q000627:therapeutic use; D001792:Blood Platelets / Q000502:physiology*; D017610:Calcium Compounds / Q000627:therapeutic use; D003789:Dental Pulp Exposure / Q000628:therapy; D003791:Dental Pulp Test; D003793:Dental Restoration, Permanent / Q000379:methods; D004338:Drug Combinations; D005260:Female; D005337:Fibrin / Q000627:therapeutic use*; D005500:Follow-Up Studies; D005899:Glass Ionomer Cements / Q000737:chemistry; D006801:Humans; D008963:Molar / Q000000981:diagnostic imaging / Q000473:pathology*; D010087:Oxides / Q000627:therapeutic use; D010513:Periodontal Ligament / Q000000981:diagnostic imaging; D011671:Pulpitis / Q000628:therapy; D011672:Pulpotomy / Q000379:methods*; D016300:Radiography, Bitewing; D012387:Root Canal Filling Materials / Q000627:therapeutic use; D017640:Silicates / Q000627:therapeutic use; D055815:Young Adult
chemical_list: D017607:Aluminum Compounds; D017610:Calcium Compounds; D004338:Drug Combinations; D005899:Glass Ionomer Cements; D010087:Oxides; D012387:Root Canal Filling Materials; D017640:Silicates; C086631:mineral trioxide aggregate; D005337:Fibrin