title: Plug and play with RNA.
abstract: Retooling RNA: RNA aptamers are high-affinity ligands that can be assembled with other structures to yield multivalent molecules. These properties have been addressed in two recent studies: One describes a GFP-like RNA reporter used to study the dynamics of endogenous RNA; the other study reports on an aptamer-templated assembly of multi-enzyme complexes in bacteria for the controlled production of secondary molecules (see picture).
authors.affiliation: Life & Medical Sciences Institute, University of Bonn, Gerhard-Domagk-Strasse 1, 53121 Bonn, Germany. gmayer@uni-bonn.de
authors.forename: Günter
authors.initials: G
authors.lastname: Mayer
authors.forename: Sabine
authors.initials: S
authors.lastname: Lennarz
authors.forename: Falk
authors.initials: F
authors.lastname: Rohrbach
authors.forename: Fabian
authors.initials: F
authors.lastname: Tolle
mesh_terms: D052157:Aptamers, Nucleotide / Q000138:chemical synthesis / Q000737:chemistry / Q000378:metabolism; D005456:Fluorescent Dyes / Q000737:chemistry; D049452:Green Fluorescent Proteins / Q000378:metabolism; D011506:Proteins / Q000737:chemistry; D012313:RNA / Q000138:chemical synthesis / Q000737:chemistry / Q000378:metabolism
chemical_list: D052157:Aptamers, Nucleotide; D005456:Fluorescent Dyes; D011506:Proteins; D049452:Green Fluorescent Proteins; D012313:RNA