title: Wilms' tumor metastatic to bilateral testes at presentation: case and review of the literature.
abstract: A 7-year-old male with bilateral palpable testicular masses was found to have metastatic stage IV Wilms' tumors associated with both left renal and lung lesions. The patient was treated successfully with testicular-sparing bilateral partial orchiectomies, radical nephrectomy, chemotherapy, and radiation, with 8 years free of recurrence. This is the only reported case of bilateral testicular tumors from metastatic Wilms' tumor that were present at the initial presentation. A review of the literature of all previous reported cases of metachronous or related testicular metastatic Wilms' tumors is reported.
authors.affiliation: University of Oklahoma, Department of Pediatric Urology, Oklahoma City, Oklahoma 73104, USA. blake-palmer@ouhsc.edu
authors.forename: Blake W
authors.initials: BW
authors.lastname: Palmer
authors.forename: Yan
authors.initials: Y
authors.lastname: Xiong
authors.forename: Awet
authors.initials: A
authors.lastname: Gherezghiher
authors.forename: David
authors.initials: D
authors.lastname: Buethe
authors.forename: Adam
authors.initials: A
authors.lastname: Metwalli
authors.forename: Dominic
authors.initials: D
authors.lastname: Frimberger
authors.forename: Bradley P
authors.initials: BP
authors.lastname: Kropp
mesh_terms: D002648:Child; D003131:Combined Modality Therapy; D006801:Humans; D007680:Kidney Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery; D008175:Lung Neoplasms / Q000188:drug therapy / Q000532:radiotherapy / Q000556:secondary; D008297:Male; D009392:Nephrectomy; D009919:Orchiectomy; D013736:Testicular Neoplasms / Q000188:drug therapy / Q000532:radiotherapy / Q000556:secondary* / Q000601:surgery; D009396:Wilms Tumor / Q000188:drug therapy / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery