title: A master CLOCK hard at work brings rhythm to the transcriptome.
abstract: In this issue of Genes & Development, Abruzzi et al. (pp. 2374-2386) use chromatin immunoprecipitation (ChIP) tiling array assays (ChIP-chip) to show that physical interactions between circadian (≅24-h) clock machineries and genomes are more widespread than previously thought and provide novel insights into how clocks drive daily rhythms in global gene expression.
authors.affiliation: Department of Molecular Biology and Biochemistry, Rutgers University, Piscataway, New Jersey 08854, USA. edery@cabm.rutgers.edu
authors.forename: Isaac
authors.initials: I
authors.lastname: Edery
mesh_terms: D000818:Animals; D056926:CLOCK Proteins / Q000235:genetics* / Q000378:metabolism*; D002940:Circadian Rhythm / Q000235:genetics*; D004330:Drosophila / Q000502:physiology*; D029721:Drosophila Proteins / Q000235:genetics* / Q000378:metabolism*; D005786:Gene Expression Regulation
chemical_list: C120526:Clk protein, Drosophila; D029721:Drosophila Proteins; D056926:CLOCK Proteins
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