title: Human leucocyte antigen-G: expression and function in airway allergic disease.
abstract: Human leucocyte antigen-G (HLA-G) is a non-classical HLA class I molecule demonstrated originally in placental trophoblast cells. Recognition of the importance of HLA-G to the maternal immune accommodation of the semi-allogeneic fetus has led to investigations of its role in the suppression of immune responses and induction of tolerance. More recently, HLA-G has been shown to have increased expression in several immunological diseases including asthma and allergic rhinitis. The focus of this review is the potential role of HLA-G in immunological airway diseases.
authors.affiliation: Department of Medicine, The University of Chicago, Chicago, IL 60637, USA. swhite@medicine.bsd.uchicago.edu
authors.forename: S R
authors.initials: SR
authors.lastname: White
mesh_terms: D001249:Asthma / Q000276:immunology* / Q000378:metabolism; D005786:Gene Expression Regulation / Q000276:immunology*; D059951:HLA-G Antigens / Q000096:biosynthesis / Q000276:immunology*; D006801:Humans; D007108:Immune Tolerance; D006255:Rhinitis, Allergic, Seasonal / Q000276:immunology* / Q000378:metabolism
chemical_list: D059951:HLA-G Antigens