title: Potential applications of microRNAs in cancer diagnosis, prognosis, and treatment.
abstract: Early studies have established that microRNAs (miRNAs) are widely deregulated in cancer and play a critical role in cancer pathogenesis. Recent research efforts are directed now towards translating these basic discoveries into novel tests or treatments that could improve the diagnosis and outcome of cancer patients. In this review, we will summarize the potential applications of miRNAs for cancer diagnosis, prognosis, and treatment. In addition, we will discuss current pitfalls and future directions.
authors.affiliation: Molecular and Cellular Developmental Biology Program and Department of Molecular Virology, Immunology and Medical Genetics, The Ohio State University Medical Center, Columbus, OH, USA.
authors.forename: Sukhinder
authors.initials: S
authors.lastname: Sandhu
authors.forename: Ramiro
authors.initials: R
authors.lastname: Garzon
mesh_terms: D006801:Humans; D035683:MicroRNAs / Q000032:analysis / Q000502:physiology*; D009369:Neoplasms / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy; D011379:Prognosis
chemical_list: D035683:MicroRNAs