title: International spread of MDR TB from Tugela Ferry, South Africa.
abstract: We describe a death associated with multidrug-resistant tuberculosis and HIV infection outside Africa that can be linked to Tugela Ferry (KwaZulu-Natal, South Africa), the town most closely associated with the regional epidemic of drug-resistant tuberculosis. This case underscores the international relevance of this regional epidemic, particularly among health care workers.
authors.affiliation: Imperial College, London, UK. g.cooke@imperial.ac.uk
authors.forename: Graham S
authors.initials: GS
authors.lastname: Cooke
authors.forename: R Kate
authors.initials: RK
authors.lastname: Beaton
authors.forename: Richard J
authors.initials: RJ
authors.lastname: Lessells
authors.forename: Laurence
authors.initials: L
authors.lastname: John
authors.forename: Simon
authors.initials: S
authors.lastname: Ashworth
authors.forename: Onn Min
authors.initials: OM
authors.lastname: Kon
authors.forename: O Martin
authors.initials: OM
authors.lastname: Williams
authors.forename: P
authors.initials: P
authors.lastname: Supply
authors.forename: P
authors.initials: P
authors.lastname: Moodley
authors.forename: Alexander S
authors.initials: AS
authors.lastname: Pym
mesh_terms: D000328:Adult; D001426:Bacterial Proteins / Q000235:genetics; D015862:Choroid Diseases / Q000473:pathology; D012321:DNA-Directed RNA Polymerases; D017809:Fatal Outcome; D005838:Genotype; D015658:HIV Infections / Q000150:complications; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D009154:Mutation; D009169:Mycobacterium tuberculosis / Q000235:genetics / Q000302:isolation & purification; D013019:South Africa / Q000453:epidemiology; D018088:Tuberculosis, Multidrug-Resistant / Q000150:complications / Q000175:diagnosis* / Q000453:epidemiology
chemical_list: D001426:Bacterial Proteins; C505805:rpoB protein, Mycobacterium tuberculosis; D012321:DNA-Directed RNA Polymerases
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