title: WikiPathways: building research communities on biological pathways.
abstract: Here, we describe the development of WikiPathways (http://www.wikipathways.org), a public wiki for pathway curation, since it was first published in 2008. New features are discussed, as well as developments in the community of contributors. New features include a zoomable pathway viewer, support for pathway ontology annotations, the ability to mark pathways as private for a limited time and the availability of stable hyperlinks to pathways and the elements therein. WikiPathways content is freely available in a variety of formats such as the BioPAX standard, and the content is increasingly adopted by external databases and tools, including Wikipedia. A recent development is the use of WikiPathways as a staging ground for centrally curated databases such as Reactome. WikiPathways is seeing steady growth in the number of users, page views and edits for each pathway. To assess whether the community curation experiment can be considered successful, here we analyze the relation between use and contribution, which gives results in line with other wiki projects. The novel use of pathway pages as supplementary material to publications, as well as the addition of tailored content for research domains, is expected to stimulate growth further.
authors.affiliation: Department of Bioinformatics-BiGCaT, Maastricht University, Maastricht, The Netherlands. thomaskelder@gmail.com
authors.forename: Thomas
authors.initials: T
authors.lastname: Kelder
authors.forename: Martijn P
authors.initials: MP
authors.lastname: van Iersel
authors.forename: Kristina
authors.initials: K
authors.lastname: Hanspers
authors.forename: Martina
authors.initials: M
authors.lastname: Kutmon
authors.forename: Bruce R
authors.initials: BR
authors.lastname: Conklin
authors.forename: Chris T
authors.initials: CT
authors.lastname: Evelo
authors.forename: Alexander R
authors.initials: AR
authors.lastname: Pico
mesh_terms: D019295:Computational Biology; D016208:Databases, Factual; D005796:Genes; D020407:Internet; D053858:Metabolic Networks and Pathways / Q000235:genetics; D011506:Proteins / Q000378:metabolism
chemical_list: D011506:Proteins
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