title: Adiponectin and pro-inflammatory cytokines in obese diabetic boys.
abstract: Adiponectin serum levels were significantly lower in obese diabetic than in non-obese healthy boys (P <0.001). Circulating soluble E-selectin levels was significantly higher in obese diabetic boys than the healthy non-obese (P <0.01). There were significant inverse correlations between adiponectin and sE-selectin, hsCRP, IL-1b, and MCP-1 and positively with NOx. We conclude that sE-selectin and MCP-1 may represent a link between obesity and related co-morbidities in children and adults.
authors.forename: Hala O
authors.initials: HO
authors.lastname: El-Mesallamy
authors.forename: Nadia M
authors.initials: NM
authors.lastname: Hamdy
authors.forename: Sherine M
authors.initials: SM
authors.lastname: Ibrahim
mesh_terms: D052242:Adiponectin / Q000097:blood*; D000293:Adolescent; D000328:Adult; D015992:Body Mass Index; D002097:C-Reactive Protein / Q000378:metabolism; D016022:Case-Control Studies; D018932:Chemokine CCL2 / Q000097:blood; D002648:Child; D016207:Cytokines / Q000097:blood*; D003924:Diabetes Mellitus, Type 2 / Q000097:blood*; D019040:E-Selectin / Q000097:blood; D006801:Humans; D008297:Male; D009569:Nitric Oxide / Q000097:blood; D009765:Obesity / Q000097:blood*
chemical_list: D052242:Adiponectin; C111835:CCL2 protein, human; D018932:Chemokine CCL2; D016207:Cytokines; D019040:E-Selectin; D009569:Nitric Oxide; D002097:C-Reactive Protein