title: Important technical remarks on distal pancreatectomy with en-bloc celiac axis resection for locally advanced pancreatic body cancer (with video).
abstract: BACKGROUND
  We have already reported the feasibility, safety, and excellent long-term results of distal pancreatectomy with en-bloc celiac axis resection (DP-CAR) for locally advanced pancreatic body cancer. An international standard for the surgical technique of DP-CAR has yet to be established.
  
  
  METHODS
  DP-CAR was carefully performed in 42 patients in Hokkaido University Hospital from 1998 to July 2007. Arterial blood flow alteration and collateral flow development toward the liver and stomach was obtained following preoperative routine transcatheter arterial embolization of the common hepatic artery. The right-sided approach to the superior mesenteric artery and celiac artery, and the preservation of the inferior pancreatoduodenal artery during the dissection of the plexus around the pancreatic head, are the key techniques in DP-CAR.
  
  
  RESULTS
  The operative morbidity and mortality were 43 and 4.8%, respectively. R0 resection could be done in 39 (93%) patients. Median operation time and intraoperative blood loss were 478 min and 1030 ml, respectively. Ischemic gastropathy was complicated in 5 (12%) patients, but liver abscess was found in only one patient and no liver failure was encountered.
  
  
  CONCLUSIONS
  We emphasize again the feasibility and safety of DP-CAR; it should be a treatment of choice for locally advanced pancreatic body cancer.
authors.affiliation: Division of Cancer Diagnostics and Therapeutics, Hokkaido University Graduate School of Medicine, Sapporo, 060-8638, Japan. etanaka@gj9.so-net.ne.jp
authors.forename: Eiichi
authors.initials: E
authors.lastname: Tanaka
authors.forename: Satoshi
authors.initials: S
authors.lastname: Hirano
authors.forename: Takahiro
authors.initials: T
authors.lastname: Tsuchikawa
authors.forename: Kentaro
authors.initials: K
authors.lastname: Kato
authors.forename: Joe
authors.initials: J
authors.lastname: Matsumoto
authors.forename: Toshiaki
authors.initials: T
authors.lastname: Shichinohe
mesh_terms: D002445:Celiac Artery / Q000601:surgery*; D003097:Collateral Circulation; D005240:Feasibility Studies; D005500:Follow-Up Studies; D006801:Humans; D008099:Liver / Q000098:blood supply*; D017538:Mesenteric Artery, Superior / Q000601:surgery*; D009367:Neoplasm Staging; D010180:Pancreatectomy / Q000379:methods; D010190:Pancreatic Neoplasms / Q000098:blood supply / Q000473:pathology / Q000601:surgery*; D013270:Stomach / Q000098:blood supply*; D013997:Time Factors; D016896:Treatment Outcome