title: Effect of denture adhesive on the micro-organisms in vivo.
abstract: BACKGROUND
  Denture adhesives increase the retention and stability of dentures in edentulous patients, especially in cases where salivary flow is impaired or in the management of traumatised oral mucosa.
  
  
  OBJECTIVE
  The effect of a denture adhesive on the oral flora at different time intervals.
  
  
  METHODS
  Thirty denture-wearing patients were involved in this study. While half of the group received a denture adhesive, the other half did not. At baseline, 1 and 2 months after delivering the dentures, smear samples were obtained from the saliva, palate and the dentures. Candida albicans, Candida krusei, Candida glabrata, Candida spp., Staphylococcus aureus, Moraxella catarrhalis, α-haemolytic streptococci, β-haemolytic streptococci, Pneumococcus aureus, S. anginosus, S. intermedius, S. constellatus, S. sanguis, S. gordonii, S. mitis, S. mutans, S. salivarius, and yeasts were investigated. The data were statistically analysed using anova and repeated measures.
  
  
  RESULTS
  Most types of the micro-organisms were not seen and could not be analysed statistically except α-haemolytic streptococci and C. albicans. No statistically significant difference was found for α-haemolytic streptococci and C. albicans in saliva, palate and the denture at all time intervals.
  
  
  CONCLUSIONS
  Prolonged use of the denture adhesive tested up to 2 months did not yield to increase in micro-organisms of the oral flora.
authors.affiliation: Department of Prosthodontics, Faculty of Dentistry, Marmara University, Istanbul, Turkey. ykozkan@marmara.edu.tr
authors.forename: Yasemin Kulak
authors.initials: YK
authors.lastname: Ozkan
authors.forename: Mert
authors.initials: M
authors.lastname: Uçankale
authors.forename: Mutlu
authors.initials: M
authors.lastname: Ozcan
authors.forename: Nurver
authors.initials: N
authors.lastname: Uner
mesh_terms: D000269:Adhesives / Q000009:adverse effects*; D000368:Aged; D001419:Bacteria / Q000187:drug effects; D002175:Candida / Q000187:drug effects; D003781:Denture Retention; D003824:Denture, Complete / Q000382:microbiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009061:Mouth Mucosa / Q000382:microbiology; D012463:Saliva / Q000382:microbiology
chemical_list: D000269:Adhesives