title: Copper-mediated chelation-assisted ortho nitration of (hetero)arenes.
abstract: A novel copper-mediated chelation-assisted ortho C-H nitration of (hetero)arenes has been developed for the first time, which used dioxygen as terminal oxidant and 1,2,3-TCP as solvent, leading to the synthesis of nitroaromatics with excellent regioselectivity and in good yields. Mechanistic investigations indicate a mechanism involving a four-centered transition state, with simultaneous cleavage of an ortho C-H bond and a N-O bond of the nitrate anion on the 2-arylpyridine-coordinated copper(II) complex.
authors.affiliation: Department of Chemistry, Northeast Normal University, Changchun 130024, China.
authors.forename: Lin
authors.initials: L
authors.lastname: Zhang
authors.forename: Zhenhua
authors.initials: Z
authors.lastname: Liu
authors.forename: Huiqin
authors.initials: H
authors.lastname: Li
authors.forename: Guichun
authors.initials: G
authors.lastname: Fang
authors.forename: Badru-Deen
authors.initials: BD
authors.lastname: Barry
authors.forename: Tuemay Abadi
authors.initials: TA
authors.lastname: Belay
authors.forename: Xihe
authors.initials: X
authors.lastname: Bi
authors.forename: Qun
authors.initials: Q
authors.lastname: Liu