title: [Metachronous urothelial cancer in bilateral upper urinary tracts and bladder associated with hereditary nonpolyposis colorectal cancer].
abstract: A 40-year-old man had undergone right hemicolectomy and sigmoidectomy under the diagnosis of ascending and sigmoid colon cancer and right nephroureterectomy under the diagnosis of right ureteral cancer, in 1997 and in 2002, respectively. In 2007, He visited our hospital with a complaint of bloody stool and hematuria. Colon fiberscopy, ureteropelvicscopy and cystoscopy demonstrated colon cancer, left renal pelvis cancer and bladder cancer, respectively, as diagnosed by biopsies, followed by restative colectomy, left nephroureterectomy and cystectomy. The final histopathological examination showed well differentiated adenocarcinoma (pSM) in the colon, and urothelial carcinoma in the left renal pelvis (pT2) and the bladder (pT1). Since his uncle and elder brother had suffered from stomach cancer and colon cancer, respectively, he was diagnosed with hereditary nonpolyposis colorectal cancer (HNPCC : Lynch syndrome). He has been well doing without recurrence for 3 years after the surgery.
authors.affiliation: The Department of Urology, Hyogo College of Medicine, Japan.
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Yamada
authors.forename: Yasuo
authors.initials: Y
authors.lastname: Ueda
authors.forename: Yoshihide
authors.initials: Y
authors.lastname: Higuchi
authors.forename: Toru
authors.initials: T
authors.lastname: Suzuki
authors.forename: Takuo
authors.initials: T
authors.lastname: Maruyama
authors.forename: Yoshinobu
authors.initials: Y
authors.lastname: Kondoh
authors.forename: Michio
authors.initials: M
authors.lastname: Nojima
authors.forename: Masashi
authors.initials: M
authors.lastname: Noda
authors.forename: Naohiro
authors.initials: N
authors.lastname: Tomita
authors.forename: Masataka
authors.initials: M
authors.lastname: Zozumi
authors.forename: Seiichi
authors.initials: S
authors.lastname: Hirota
authors.forename: Shingo
authors.initials: S
authors.lastname: Yamamoto
mesh_terms: D000328:Adult; D003123:Colorectal Neoplasms, Hereditary Nonpolyposis / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007680:Kidney Neoplasms / Q000473:pathology* / Q000601:surgery; D007682:Kidney Pelvis; D008297:Male; D016609:Neoplasms, Second Primary / Q000473:pathology* / Q000601:surgery; D001749:Urinary Bladder Neoplasms / Q000473:pathology* / Q000601:surgery