title: The SEQanswers wiki: a wiki database of tools for high-throughput sequencing analysis.
abstract: Recent advances in sequencing technology have created unprecedented opportunities for biological research. However, the increasing throughput of these technologies has created many challenges for data management and analysis. As the demand for sophisticated analyses increases, the development time of software and algorithms is outpacing the speed of traditional publication. As technologies continue to be developed, methods change rapidly, making publications less relevant for users. The SEQanswers wiki (SEQwiki) is a wiki database that is actively edited and updated by the members of the SEQanswers community (http://SEQanswers.com/). The wiki provides an extensive catalogue of tools, technologies and tutorials for high-throughput sequencing (HTS), including information about HTS service providers. It has been implemented in MediaWiki with the Semantic MediaWiki and Semantic Forms extensions to collect structured data, providing powerful navigation and reporting features. Within 2 years, the community has created pages for over 500 tools, with approximately 400 literature references and 600 web links. This collaborative effort has made SEQwiki the most comprehensive database of HTS tools anywhere on the web. The wiki includes task-focused mini-reviews of commonly used tools, and a growing collection of more than 100 HTS service providers. SEQwiki is available at: http://wiki.SEQanswers.com/.
authors.affiliation: School of Life Sciences, The Chinese University of Hong Kong, Shatin, NT, Hong Kong SAR. dan.bolser@gmail.com
authors.forename: Jing-Woei
authors.initials: JW
authors.lastname: Li
authors.forename: Keith
authors.initials: K
authors.lastname: Robison
authors.forename: Marcel
authors.initials: M
authors.lastname: Martin
authors.forename: Andreas
authors.initials: A
authors.lastname: Sjödin
authors.forename: Björn
authors.initials: B
authors.lastname: Usadel
authors.forename: Matthew
authors.initials: M
authors.lastname: Young
authors.forename: Eric C
authors.initials: EC
authors.lastname: Olivares
authors.forename: Dan M
authors.initials: DM
authors.lastname: Bolser
mesh_terms: D019295:Computational Biology; D030561:Databases, Nucleic Acid; D059014:High-Throughput Nucleotide Sequencing; D020407:Internet; D012984:Software
references.citation: Genome Biol. 2007;8(1):102
references.pmid: 17274839
references.citation: Nature. 2005 Dec 1;438(7068):548-9
references.pmid: 16319855
references.citation: Nature. 2008 Sep 4;455(7209):22-5
references.pmid: 18769412
references.citation: Genome Res. 2011 Dec;21(12):2224-41
references.pmid: 21926179
references.citation: J Pers Soc Psychol. 2000 Dec;79(6):995-1006
references.pmid: 11138768
references.citation: Science. 2008 Mar 21;319(5870):1598-9
references.pmid: 18356493
references.citation: Science. 2008 Jun 6;320(5881):1289-90
references.pmid: 18535227