title: Colonic stenting as a bridge to surgery in malignant large-bowel obstruction: a report from two large multinational registries.
abstract: OBJECTIVE
  To date, this is the largest prospective series in patients with malignant colorectal obstruction to evaluate the effectiveness and safety of colonic self-expanding metal stents (SEMSs) as an alternative to emergency surgery. SEMSs allow restoration of bowel transit and careful tumor staging in preparation for elective surgery, hence avoiding the high morbidity and mortality associated with emergency surgery and stoma creation.
  
  
  METHODS
  This report is on the SEMS bridge-to-surgery subset enrolled in two multicenter international registries. Patients were treated per standard of practice, with documentation of clinical and procedural success, safety, and surgical outcomes.
  
  
  RESULTS
  A total of 182 patients were enrolled with obstructive tumor in the left colon (85%), rectum (11%), or splenic flexure (4%). Of these patients, 86% had localized colorectal cancer without metastasis. Procedural success was 98% (177/181). Clinical success was 94% (141/150). Elective surgery was performed in 150 patients (9 stomas) and emergency surgery in 7 patients for treatment of a complication (3 stomas). The overall complication rate was 7.8% (13/167), including perforation in 3% (5/167), stent migration in 1.2% (2/167), bleeding in 0.6% (1/167), persistent colonic obstruction in 1.8% (3/167), and stent occlusion due to fecal impaction in 1.2% (2/167). One patient died from complications related to surgical management of a perforation.
  
  
  CONCLUSIONS
  SEMSs provide an effective bridge to surgery treatment with an acceptable complication rate in patients with acute malignant colonic obstruction, restoring luminal patency and allowing elective surgery with primary anastomosis in most patients.
authors.affiliation: Department of Gastroenterology, Hospital de Navarra, Pamplona, Spain. jjimenezpster@gmail.com
authors.forename: J
authors.initials: J
authors.lastname: Jiménez-Pérez
authors.forename: J
authors.initials: J
authors.lastname: Casellas
authors.forename: J
authors.initials: J
authors.lastname: García-Cano
authors.forename: J
authors.initials: J
authors.lastname: Vandervoort
authors.forename: O Roncero
authors.initials: OR
authors.lastname: García-Escribano
authors.forename: J
authors.initials: J
authors.lastname: Barcenilla
authors.forename: A Alvarez
authors.initials: AA
authors.lastname: Delgado
authors.forename: P
authors.initials: P
authors.lastname: Goldberg
authors.forename: F
authors.initials: F
authors.lastname: Gonzalez-Huix
authors.forename: E
authors.initials: E
authors.lastname: Vázquez-Astray
authors.forename: S
authors.initials: S
authors.lastname: Meisner
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015331:Cohort Studies; D003113:Colonoscopy; D015179:Colorectal Neoplasms / Q000150:complications / Q000628:therapy*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007415:Intestinal Obstruction / Q000150:complications / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D057234:Preoperative Period; D011446:Prospective Studies; D012042:Registries; D015607:Stents; D016896:Treatment Outcome