title: Ammonia transport by terrestrial and aquatic insects.
abstract: Ammonia, an end product from amino acid and nucleic acid metabolism, is highly toxic for most animals. This review will provide an update on nitrogen metabolism in terrestrial and aquatic insects with emphasis on ammonia generation and transport. Aspects that will be discussed include metabolic pathways of nitrogenous compounds, the origin of ammonia and other nitrogenous waste products, ammonia toxicity, putative ammonia transporters as well as ammonia transport processes known in insects. Ammonia transport mechanisms in the mosquito Aedes aegypti, the tobacco hornworm Manduca sexta and the locust Schistocerca gregaria will be discussed in detail while providing additional, novel data.
authors.affiliation: Department of Biological Sciences, University of Manitoba, Winnipeg, MB, Canada R3T2N2. weihrauc@cc.umanitoba.ca
authors.forename: Dirk
authors.initials: D
authors.lastname: Weihrauch
authors.forename: Andrew
authors.initials: A
authors.lastname: Donini
authors.forename: Michael J
authors.initials: MJ
authors.lastname: O'Donnell
mesh_terms: D000595:Amino Acid Sequence; D000641:Ammonia / Q000378:metabolism* / Q000633:toxicity; D000818:Animals; D059001:Aquatic Organisms / Q000378:metabolism; D001692:Biological Transport; D027682:Cation Transport Proteins / Q000378:metabolism; D007313:Insecta / Q000378:metabolism*; D008969:Molecular Sequence Data; D009584:Nitrogen / Q000378:metabolism
chemical_list: D027682:Cation Transport Proteins; D000641:Ammonia; D009584:Nitrogen