title: A concise total synthesis of (±)-minfiensine.
abstract: A concise total synthesis of (±)-minfiensine using all conventional methods and starting from commercial materials has been completed. The synthesis features a Fischer indole synthesis, a Heck alkylation of an intermediate ketone enolate, conversion of a ketone carbonyl into an epoxide, and transformation of the latter into an allylic alcohol.
authors.affiliation: Laboratory of Molecular Engineering, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, 190 Kaiyuan Avenue, Guangzhou 510530, China.
authors.forename: Peijun
authors.initials: P
authors.lastname: Liu
authors.forename: Juan
authors.initials: J
authors.lastname: Wang
authors.forename: Jiancun
authors.initials: J
authors.lastname: Zhang
authors.forename: Fayang G
authors.initials: FG
authors.lastname: Qiu
mesh_terms: D000470:Alkaloids / Q000138:chemical synthesis* / Q000737:chemistry; D000478:Alkylation; D002227:Carbazoles / Q000138:chemical synthesis* / Q000737:chemistry; D003500:Cyclization; D004852:Epoxy Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D007659:Ketones / Q000737:chemistry*; D013237:Stereoisomerism; D031451:Strychnos / Q000737:chemistry
chemical_list: D000470:Alkaloids; D002227:Carbazoles; D004852:Epoxy Compounds; D007659:Ketones; C504098:minfiensine