title: Palladium-catalyzed oxidative arylalkylation of activated alkenes: dual C-H bond cleavage of an arene and acetonitrile.
abstract: Not one but two: The title reaction proceeds through the dual C-H bond cleavage of both aniline and acetonitrile. The reaction affords a variety of cyano-bearing indolinones in excellent yield. Mechanistic studies demonstrate that this reaction involves a fast arylation of the olefin and a rate-determining C-H activation of the acetonitrile.
authors.affiliation: State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai, 200032, China.
authors.forename: Tao
authors.initials: T
authors.lastname: Wu
authors.forename: Xin
authors.initials: X
authors.lastname: Mu
authors.forename: Guosheng
authors.initials: G
authors.lastname: Liu
mesh_terms: D000097:Acetonitriles / Q000737:chemistry*; D000473:Alkanes / Q000138:chemical synthesis* / Q000737:chemistry; D000475:Alkenes / Q000737:chemistry*; D000478:Alkylation; D047250:Calixarenes / Q000737:chemistry*; D002384:Catalysis; D015394:Molecular Structure; D010084:Oxidation-Reduction; D010165:Palladium / Q000737:chemistry*
chemical_list: D000097:Acetonitriles; D000473:Alkanes; D000475:Alkenes; D047250:Calixarenes; D010165:Palladium; C032159:acetonitrile