title: [Neuroendoscopic treatment for 372 cases of intracranial lesions].
abstract: OBJECTIVE
  To explore the application of neuroendoscopic treatment for intracranial lesions.
  
  
  METHODS
  The clinic data of 372 patients with intracranial lesions, who underwent neuroendoscopic treatment at our department from May 1998 to May 2010, were reviewed retrospectively. Representative endoscopic treatments included endoscopic third ventriculostomy (ETV) (n = 198), ETV & endoscopic biopsy (n = 69), neuroendoscopic ostomy for septum pellucidum fenestration (n = 55) (for septum pellucidum cysts, n = 37) and endoscopic cystoventriculostomy for ventricular cysts (n = 50). Their surgical indications and clinical outcomes were summarized for analysis.
  
  
  RESULTS
  ETV was performed successfully in 369 cases. Among them, 2 failed cases underwent other operations and endoscopic biopsy failed in 1 case. Within a short post-operative period, the symptoms were resolved in 347 cases (93.3%), showed no improvement in 23 cases (6.2%) and 2 died (0.5%). At Month 6 post-operation, a failure of ETV was detected in 22 cases (9.5%), a failure of neuroendoscopic ostomy for septum pellucidum cysts in 23 (69.7%) and for ventricular cysts in 12 cases (26.7%).
  
  
  CONCLUSIONS
  ETV is effective in the treatment of obstructive hydrocephalus, but its indication should be strictly controlled for children. Effective rate of neuroendoscopic treatment for intracranial septum pellucidum cysts remains unsatisfactory so that its operative indication should be strictly controlled.
authors.affiliation: Department of Neurosurgery, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510080, China. zhanshengquan@126.com
authors.forename: Sheng-Quan
authors.initials: SQ
authors.lastname: Zhan
authors.forename: Zhao-Jie
authors.initials: ZJ
authors.lastname: Li
authors.forename: Dong
authors.initials: D
authors.lastname: Zhou
authors.forename: Zhi-Jun
authors.initials: ZJ
authors.lastname: Lin
authors.forename: Kai
authors.initials: K
authors.lastname: Tang
authors.forename: Xiao-Feng
authors.initials: XF
authors.lastname: Lin
authors.forename: Peng
authors.initials: P
authors.lastname: Wang
authors.forename: Hang
authors.initials: H
authors.lastname: Shu
authors.forename: De-Xiang
authors.initials: DX
authors.lastname: Zhou
authors.forename: Yan-Wen
authors.initials: YW
authors.lastname: Li
authors.forename: Wen-Long
authors.initials: WL
authors.lastname: Guo
authors.forename: Cheng-Liang
authors.initials: CL
authors.lastname: Mao
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001927:Brain Diseases / Q000601:surgery*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D006849:Hydrocephalus / Q000601:surgery; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D044583:Neuroendoscopy; D010030:Ostomy / Q000379:methods*; D012189:Retrospective Studies; D016896:Treatment Outcome; D014696:Ventriculostomy; D055815:Young Adult