title: Taste learning and memory: a window on the study of brain aging.
abstract: Taste aversion learning exhibits advantages for research on memory brain systems and its reorganization throughout life. A review of the effects of aging on taste memory abilities offers a complex picture showing preserved, impaired, and enhanced functions. Some of the age-related changes in taste memory seem to be associated with an altered temporal processing. Longer taste-illness delays can be introduced for acquisition of conditioned taste aversions and the modulation of taste learning by the temporal context is absent in naïve old rats. It is suggested that an altered hippocampal function is involved in the peculiar performance of these rats. Evidence is also presented which suggests that hippocampal-dependent taste memory can be reactivated by previous learning experiences in old rats. Results obtained after reversible inactivation of the dorsal Hippocampus by tetrodotoxin (TTX) in old rats support such a view. Therefore, the interaction between the previous experience and acute brain interventions should be taken into account when studying the effect of aging on taste memory.
authors.affiliation: Department of Psychobiology, Centre for Biomedical Research, Institute of Neuroscience, University of Granada Granada, Spain.
authors.forename: Fernando
authors.initials: F
authors.lastname: Gámiz
authors.forename: Milagros
authors.initials: M
authors.lastname: Gallo
references.citation: Learn Mem. 2002 Sep-Oct;9(5):218-23
references.pmid: 12359831
references.citation: Psychol Rep. 1995 Apr;76(2):636-8
references.pmid: 7667477
references.citation: Neurobiol Aging. 2004 Feb;25(2):209-21
references.pmid: 14749139
references.citation: J Neurophysiol. 2004 Mar;91(3):1143-57
references.pmid: 14627662
references.citation: Chem Senses. 2005 Jan;30 Suppl 1:i160-1
references.pmid: 15738091
references.citation: Behav Brain Res. 1997 Oct;88(1):67-74
references.pmid: 9401710
references.citation: Percept Mot Skills. 1995 Apr;80(2):595-8
references.pmid: 7675599
references.citation: Neurobiol Learn Mem. 2002 Jul;78(1):167-77
references.pmid: 12071673
references.citation: Nat Rev Neurosci. 2004 Mar;5(3):209-17
references.pmid: 14976520
references.citation: Neuropsychologia. 2010 Mar;48(4):1022-31
references.pmid: 19962999
references.citation: J Vet Med Sci. 2003 Mar;65(3):313-7
references.pmid: 12679559
references.citation: Chem Senses. 2007 Jan;32(1):111-7
references.pmid: 17110525
references.citation: Physiol Behav. 2009 Aug 4;98(1-2):103-7
references.pmid: 19394353
references.citation: Neurobiol Learn Mem. 2004 Sep;82(2):77-80
references.pmid: 15341792
references.citation: Physiol Behav. 1975 Jun;14(6):809-13
references.pmid: 1187836
references.citation: J Acoust Soc Am. 2004 Aug;116(2):1126-34
references.pmid: 15376678
references.citation: Front Syst Neurosci. 2011 Nov 23;5:87
references.pmid: 22131967
references.citation: Neurobiol Learn Mem. 2006 May;85(3):199-205
references.pmid: 16321549
references.citation: Behav Neurosci. 2008 Feb;122(1):54-62
references.pmid: 18298249
references.citation: Physiol Behav. 2007 Feb 28;90(2-3):308-17
references.pmid: 17112552
references.citation: Behav Neural Biol. 1985 Jul;44(1):122-31
references.pmid: 3834916
references.citation: Front Syst Neurosci. 2011 Sep 05;5:76
references.pmid: 21922004
references.citation: Hippocampus. 2009 Jan;19(1):57-65
references.pmid: 18680140
references.citation: Physiol Behav. 2002 Apr 15;75(5):759-64
references.pmid: 12020741
references.citation: Behav Brain Res. 2008 Mar 17;188(1):56-61
references.pmid: 18061286
references.citation: Exp Aging Res. 1980 Apr;6(2):113-23
references.pmid: 7389781
references.citation: Physiol Behav. 1997 Feb;61(2):221-4
references.pmid: 9035251
references.citation: Learn Mem. 2005 Nov-Dec;12(6):547-8
references.pmid: 16322357
references.citation: Pharmacol Biochem Behav. 1993 Oct;46(2):415-21
references.pmid: 8265697
references.citation: Physiol Res. 2002;51 Suppl 1:S21-7
references.pmid: 12479783
references.citation: J Comp Physiol Psychol. 1959 Aug;52:415-9
references.pmid: 14418647
references.citation: Psychol Rep. 1989 Apr;64(2):611-4
references.pmid: 2540504
references.citation: Neurobiol Aging. 2004 Jan;25(1):3-4
references.pmid: 14675723
references.citation: Psychol Rep. 1994 Aug;75(1 Pt 1):267-71
references.pmid: 7984736
references.citation: Nutr Neurosci. 1999;2(5):277-302
references.pmid: 27415802
references.citation: Behav Neural Biol. 1983 Nov;39(2):181-91
references.pmid: 6670971
references.citation: J Exp Psychol Anim Behav Process. 1977 Apr;3(2):132-43
references.pmid: 853271
references.citation: Neurobiol Aging. 2012 Aug;33(8):1744-57
references.pmid: 21531046
references.citation: Percept Mot Skills. 1993 Dec;77(3 Pt 2):1403-6
references.pmid: 8170797
references.citation: Physiol Behav. 1980 May;24(5):979-82
references.pmid: 7403301
references.citation: Hear Res. 2010 Jun 1;264(1-2):63-9
references.pmid: 20303402
references.citation: Neurobiol Aging. 1989 Nov-Dec;10(6):691-708
references.pmid: 2628781
references.citation: Learn Mem. 2005 Nov-Dec;12(6):579-86
references.pmid: 16322360
references.citation: Neural Plast. 2008;2008:595282
references.pmid: 18584042
references.citation: Dev Psychobiol. 2002 Mar;40(2):131-7
references.pmid: 11857327