title: [Randomised controlled trial: the role of diet and exercise in women with metabolic syndrome].
abstract: OBJECTIVE
  To evaluate a program of nutritional recommendations and exercise in women with metabolic syndrome.
  
  
  METHODS
  Multicentre randomised controlled trial.
  
  
  METHODS
  Primary Health Care, Holguin, Cuba.
  
  
  METHODS
  A cluster sample of 150 obese women with metabolic syndrome without glucose disturbances, were randomly assigned to a control (n=70) or experimental (n=80) group. A total of 62 women in the control group and 60 in the intervention group completed the study (June 2008-July 2009).
  
  
  METHODS
  Low calorie diets and a program of exercises in the experimental group. Usual care in the control group.
  
  
  METHODS
  Body weight, body mass index, waist circumference, blood pressure, blood glucose and lipid profile.
  
  
  RESULTS
  Compared to the control group, after one year, the experimental group had a lower, diastolic blood pressure (78±0.9 vs 91±1.1mm Hg), total cholesterol (4.7±0.1 vs 6.0 ±0.1mmol/L), triglycerides (1.9±0.0 vs 2.9±0.1mmol/L) and LDL cholesterol (2.5±0.0 vs 3.5±0.1mmol/L), and a higher HDL-cholesterol (1.2±0.0 vs 1.1±0.0mmol/L). There were no appreciable changes in weight, body mass index, waist circumference, systolic blood pressure and blood glucose.
  
  
  CONCLUSIONS
  We demonstrated the effectiveness of the intervention program on blood pressure and blood lipid profile.
authors.affiliation: Universidad Médica Mariana Grajales Coello, Holguín, Cuba. soca@ucm.hlg.sld.cu
authors.forename: Pedro Enrique
authors.initials: PE
authors.lastname: Miguel Soca
authors.forename: Idania
authors.initials: I
authors.lastname: Peña Pérez
authors.forename: Silvio
authors.initials: S
authors.lastname: Niño Escofet
authors.forename: Walter
authors.initials: W
authors.lastname: Cruz Torres
authors.forename: Aluett
authors.initials: A
authors.lastname: Niño Peña
authors.forename: Delmis
authors.initials: D
authors.lastname: Ponce De León
mesh_terms: D004038:Diet, Reducing; D015444:Exercise; D005260:Female; D006801:Humans; D024821:Metabolic Syndrome / Q000150:complications / Q000178:diet therapy / Q000628:therapy*; D008875:Middle Aged; D009765:Obesity / Q000150:complications / Q000178:diet therapy / Q000628:therapy*; D016037:Single-Blind Method
references.citation: Obes Rev. 2005 Nov;6(4):283-96
references.pmid: 16246214
references.citation: Ann Intern Med. 2008 Feb 19;148(4):295-309
references.pmid: 18283207
references.citation: Asia Pac J Clin Nutr. 2008;17(2):229-34
references.pmid: 18586641
references.citation: Asia Pac J Clin Nutr. 2007;16(4):671-6
references.pmid: 18042527
references.citation: Asia Pac J Clin Nutr. 2008;17(4):669-71
references.pmid: 19114407
references.citation: J Fam Pract. 2007 Oct;56(10):841-2, 844
references.pmid: 17908517
references.citation: Aten Primaria. 2006 Jun 30;38(2):72-9
references.pmid: 16828009
references.citation: Tohoku J Exp Med. 2008 Aug;215(4):355-61
references.pmid: 18679010
references.citation: Ann Clin Biochem. 2008 Mar;45(Pt 2):122-8
references.pmid: 18325173
references.citation: Diabetes Care. 2007 Feb;30(2):343-7
references.pmid: 17259505
references.citation: Eur Heart J. 2007 May;28(9):1149-54
references.pmid: 17428821
references.citation: Diabetes Care. 2007 Apr;30(4):967-73
references.pmid: 17392557
references.citation: Int J Obes (Lond). 2006 Jan;30(1):112-21
references.pmid: 16231038
references.citation: J Womens Health (Larchmt). 2008 Sep;17(7):1099-110
references.pmid: 18774895
references.citation: Circulation. 2002 Dec 17;106(25):3143-421
references.pmid: 12485966
references.citation: Obes Res. 2004 May;12(5):789-98
references.pmid: 15166299
references.citation: Eur Heart J. 2008 Jan;29(2):213-23
references.pmid: 18199567
references.citation: Expert Rev Cardiovasc Ther. 2006 Nov;4(6):871-95
references.pmid: 17173503
references.citation: N Engl J Med. 2007 Sep 6;357(10):1009-17
references.pmid: 17804845
references.citation: Diabetes Care. 2005 Jun;28(6):1485-6
references.pmid: 15920073
references.citation: N Engl J Med. 2009 Feb 26;360(9):859-73
references.pmid: 19246357