title: Real-time DNA detection using Pt nanoparticle-decorated reduced graphene oxide field-effect transistors.
abstract: A large-area, continuous, few-layer reduced graphene oxide (rGO) thin film has been fabricated on a Si/SiO(2) wafer using the Langmuir-Blodgett (LB) method followed by thermal reduction. After photochemical reduction of Pt nanoparticles (PtNPs) on rGO, the obtained PtNPs/rGO composite is employed as the conductive channel in a solution-gated field effect transistor (FET), which is then used for real-time detection of hybridization of single-stranded DNA (ssDNA) with high sensitivity (2.4 nM). Such a simple, but effective method for fabrication of rGO-based transistors shows great potential for mass-production of graphene-based electronic biosensors.
authors.affiliation: School of Materials Science and Engineering, Nanyang Technological University, 50 Nanyang Avenue, Singapore.
authors.forename: Zongyou
authors.initials: Z
authors.lastname: Yin
authors.forename: Qiyuan
authors.initials: Q
authors.lastname: He
authors.forename: Xiao
authors.initials: X
authors.lastname: Huang
authors.forename: Juan
authors.initials: J
authors.lastname: Zhang
authors.forename: Shixin
authors.initials: S
authors.lastname: Wu
authors.forename: Peng
authors.initials: P
authors.lastname: Chen
authors.forename: Gang
authors.initials: G
authors.lastname: Lu
authors.forename: Peng
authors.initials: P
authors.lastname: Chen
authors.forename: Qichun
authors.initials: Q
authors.lastname: Zhang
authors.forename: Qingyu
authors.initials: Q
authors.lastname: Yan
authors.forename: Hua
authors.initials: H
authors.lastname: Zhang
mesh_terms: D004277:DNA, Single-Stranded / Q000032:analysis*; D006108:Graphite / Q000737:chemistry*; D053768:Metal Nanoparticles / Q000737:chemistry*; D009693:Nucleic Acid Hybridization; D010087:Oxides / Q000737:chemistry*; D010984:Platinum / Q000737:chemistry*; D012822:Silicon Dioxide / Q000737:chemistry; D014173:Transistors, Electronic
chemical_list: D004277:DNA, Single-Stranded; D010087:Oxides; D010984:Platinum; D012822:Silicon Dioxide; D006108:Graphite