title: Experience-dependent plasticity of mature adult-born neurons.
abstract: The adult olfactory bulb and hippocampus are continuously supplied with newborn neurons that are thought to possess a capacity for plasticity only at a young neuronal age, mainly during the early stages of integration into the network. We find that the two main types of adult-born neurons in the mouse olfactory bulb undergo experience-dependent plasticity long after maturation and integration, as evidenced by stabilization of synaptic turnover rates. Thus, the potential time window for plasticity of adult-born neurons extends well into maturity.
authors.affiliation: Department of Neurobiology, Institute of Life Sciences, The Hebrew University of Jerusalem, Edmond J. Safra Campus, Givat Ram, Jerusalem, Israel.
authors.forename: Yoav
authors.initials: Y
authors.lastname: Livneh
authors.forename: Adi
authors.initials: A
authors.lastname: Mizrahi
mesh_terms: D000818:Animals; D051379:Mice; D055495:Neurogenesis / Q000502:physiology*; D009473:Neuronal Plasticity / Q000502:physiology*; D009474:Neurons / Q000166:cytology / Q000502:physiology*; D009830:Olfactory Bulb / Q000166:cytology / Q000502:physiology*; D013569:Synapses / Q000502:physiology
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