title: Expiratory flow increase technique and acid esophageal exposure in infants born preterm with bronchopulmonary dysplasia.
abstract: OBJECTIVE
  To determine if an expiratory flow increase technique (EFIT) is associated with acid reflux episodes in infants born preterm with bronchopulmonary dysplasia (BPD).
  
  
  METHODS
  A crossover study was carried out. Eighteen subjects divided into 2 groups were randomly assigned to receive 2 EFIT sessions at 2 postprandial time points. Group 1 started 2 hours after feeding and group 2 started 3 hours after feeding. Esophageal acid exposure was assessed by the reflux index (RI) during EFIT and 20 minutes before EFIT by esophageal pH monitoring.
  
  
  RESULTS
  A significant reduction in the RI was observed in group 1 with EFIT performed 2 hours after feeding. Group 2 showed no significant differences in RI values before and during EFIT in both postprandial periods.
  
  
  CONCLUSIONS
  When EFIT is performed 2 and 3 hours after feeding, it is not associated with an increase in acid reflux episodes in infants born preterm with BPD.
authors.affiliation: Center of Integral Attention to Women's Health, University of Campinas-UNICAMP, Campinas, São Paulo, Brazil. liacamy@gmail.com
authors.forename: Lia Franco Serrou
authors.initials: LF
authors.lastname: Camy
authors.forename: Maria Aparecida
authors.initials: MA
authors.lastname: Mezzacappa
mesh_terms: D000704:Analysis of Variance; D001997:Bronchopulmonary Dysplasia / Q000150:complications* / Q000473:pathology; D018592:Cross-Over Studies; D050782:Esophageal pH Monitoring; D005260:Female; D005764:Gastroesophageal Reflux / Q000209:etiology* / Q000628:therapy; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007234:Infant, Premature; D008297:Male; D026741:Physical Therapy Modalities / Q000009:adverse effects*; D012123:Pulmonary Ventilation; D018709:Statistics, Nonparametric; D016683:Supine Position; D013997:Time Factors