title: Enantioselective bromocyclization of olefins catalyzed by chiral phosphoric acid.
abstract: A chiral phosphoric acid catalyzed enantioselective bromocyclization of olefins is described. Various cis-, trans-, or trisubstituted γ-hydroxy-alkenes and γ-amino-alkenes can cyclize under the reaction conditions to give optically active 2-substituted tetrahydrofurans and tetrahydropyrroles in up to 91% ee.
authors.affiliation: Beijing National Laboratory for Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China.
authors.forename: Deshun
authors.initials: D
authors.lastname: Huang
authors.forename: Haining
authors.initials: H
authors.lastname: Wang
authors.forename: Fazhen
authors.initials: F
authors.lastname: Xue
authors.forename: Huan
authors.initials: H
authors.lastname: Guan
authors.forename: Lijun
authors.initials: L
authors.lastname: Li
authors.forename: Xianyou
authors.initials: X
authors.lastname: Peng
authors.forename: Yian
authors.initials: Y
authors.lastname: Shi