title: Triggering the production of the cryptic blue pigment indigoidine from Photorhabdus luminescens.
abstract: The production of the blue pigment indigoidine has been achieved in the entomopathogenic bacterium Photorhabdus luminescens by a promoter exchange and in Escherichia coli following heterologous expression of the biosynthesis gene indC. Moreover, genes involved in the regulation of this previously "silent" biosynthesis gene cluster have been identified in P. luminescens.
authors.affiliation: Molekulare Biotechnologie, Institut für Molekulare Biowissenschaften, Goethe Universität Frankfurt, Max-von-Laue-Str. 9, 60438 Frankfurt am Main, Germany.
authors.forename: Alexander O
authors.initials: AO
authors.lastname: Brachmann
authors.forename: Ferdinand
authors.initials: F
authors.lastname: Kirchner
authors.forename: Carsten
authors.initials: C
authors.lastname: Kegler
authors.forename: Sebastian C
authors.initials: SC
authors.lastname: Kinski
authors.forename: Imke
authors.initials: I
authors.lastname: Schmitt
authors.forename: Helge B
authors.initials: HB
authors.lastname: Bode
mesh_terms: D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism; D001499:Bayes Theorem; D003001:Cloning, Molecular; D004926:Escherichia coli / Q000235:genetics / Q000378:metabolism; D005810:Multigene Family; D020637:Photorhabdus / Q000235:genetics* / Q000378:metabolism*; D010802:Phylogeny; D010860:Pigments, Biological / Q000096:biosynthesis*; D010881:Piperidones / Q000378:metabolism*; D011401:Promoter Regions, Genetic
chemical_list: D001426:Bacterial Proteins; D010860:Pigments, Biological; D010881:Piperidones; C446045:indigoidine