title: Obesity and its impact on drug therapy: are we ready for this change?
authors.affiliation: Keck School of Medicine, University of Southern California, Los Angeles, USA.
authors.forename: Michael
authors.initials: M
authors.lastname: Neely
authors.forename: Stan
authors.initials: S
authors.lastname: Louie
mesh_terms: D005260:Female; D006801:Humans; D008297:Male; D008954:Models, Biological; D009765:Obesity / Q000378:metabolism*; D009767:Obesity, Morbid / Q000378:metabolism*; D010599:Pharmacokinetics
references.citation: Drug Metab Dispos. 2008 Feb;36(2):217-22
references.pmid: 17991769
references.citation: Biopharm Drug Dispos. 2009 Dec;30(9):532-41
references.pmid: 19862765
references.citation: Clin Pharmacokinet. 2011 Dec 1;50(12):809-22
references.pmid: 22087867
references.citation: J Clin Invest. 1995 May;95(5):2409-15
references.pmid: 7738205
references.citation: Science. 1993 Jan 1;259(5091):87-91
references.pmid: 7678183
references.citation: Clin Pharmacol Ther. 2011 Feb;89(2):259-67
references.pmid: 21191381
references.citation: J Hepatol. 2005 Dec;43(6):1021-30
references.pmid: 16139386
references.citation: Diabetes Res Clin Pract. 2006 Jan;71(1):92-100
references.pmid: 16002176
references.citation: Drug Metab Dispos. 2009 Mar;37(3):685-93
references.pmid: 19074973
references.citation: Clin Pharmacokinet. 2000 Sep;39(3):215-31
references.pmid: 11020136
references.citation: Paediatr Anaesth. 2011 Mar;21(3):222-37
references.pmid: 21320233
references.citation: Clin Pharmacokinet. 2010;49(2):71-87
references.pmid: 20067334
references.citation: JAMA. 2010 Jan 20;303(3):235-41
references.pmid: 20071471
references.citation: Biochem Soc Trans. 2005 Nov;33(Pt 5):1078-81
references.pmid: 16246049
references.citation: Mol Pharm. 2008 Jan-Feb;5(1):77-91
references.pmid: 18189363
references.citation: Science. 1996 Nov 22;274(5291):1377-9
references.pmid: 8910278
references.citation: Clin Pharmacol Ther. 2011 Jul;90(1):77-89
references.pmid: 21633345
references.citation: Arch Dis Child Educ Pract Ed. 2010 Aug;95(4):112-7
references.pmid: 20585055
references.citation: Paediatr Anaesth. 2011 Jun;21(6):623-9
references.pmid: 21429056
references.citation: Drug Metab Dispos. 2007 Sep;35(9):1687-93
references.pmid: 17576808
references.citation: Int J Pediatr Obes. 2011 Oct;6(5-6):342-60
references.pmid: 21838570
references.citation: Int J Pharm. 2011 Oct 14;418(2):151-60
references.pmid: 21803144