title: Low frequency of human papillomavirus infection in conjunctival squamous cell carcinoma of Mexican patients.
abstract: BACKGROUND
  The relationship between Human Papillomavirus (HPV) infection and conjunctiva cancer is controversial. HPV detection will provide more information about the role of this infectious agent in the biology of conjunctiva cancer. In the present study, DNA extracted and purified from 36 Conjunctival Squamous Cell Carcinomas (CSCC) was evaluated by PCR for HPV DNA sequences. The results were correlated with the clinical and histopathological variables.
  
  
  RESULTS
  The results showed that HPV DNA was present in 8 CSCC samples (22%); HPV16 was the sole type detected. Significant association was found between HPV detection and the limbus tumor subtype (p = 0.03). All the samples were non-metastatic squamous cell carcinoma.
  
  
  CONCLUSIONS
  The HPV presence in CSCC from Mexican patients is not a common event.
authors.affiliation: Laboratorio de Oncogenomica, UIMEO, Hospital de Oncología, CMN-SXXI, IMSS, Av Cuauhtemoc 330, Col, Doctores, 06720, Mexico DF, Mexico. maosal89@yahoo.com.
authors.forename: Raúl
authors.initials: R
authors.lastname: Peralta
authors.forename: Alejandra
authors.initials: A
authors.lastname: Valdivia
authors.forename: Perla
authors.initials: P
authors.lastname: Estañol
authors.forename: Vanessa
authors.initials: V
authors.lastname: Villegas
authors.forename: Carolina
authors.initials: C
authors.lastname: Pimienta
authors.forename: Eugenio
authors.initials: E
authors.lastname: Treviño
authors.forename: Daniel
authors.initials: D
authors.lastname: Marrero
authors.forename: Monica
authors.initials: M
authors.lastname: Mendoza
authors.forename: Florinda
authors.initials: F
authors.lastname: Jimenez
authors.forename: Leonardo
authors.initials: L
authors.lastname: Villalvazo
authors.forename: Miriam
authors.initials: M
authors.lastname: Tejeda
authors.forename: Mauricio
authors.initials: M
authors.lastname: Salcedo
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