title: Hepatocellular carcinoma arising from hepatocellular adenoma in a hepatitis B virus-associated cirrhotic liver.
abstract: Hepatocellular adenoma (HCA) is a rare, benign proliferation of hepatocytes that occurs mostly in a normal liver and in extreme rare cases, occurs in a cirrhotic liver. Hepatocellular carcinomas (HCC) arising within HCA through malignant transformation is rare. The specific incidence and mechanism of malignant transformation has not been established, but the long term use of oral contraceptives is considered a causative agent. We report a case of HCC arising from HCA detected in a hepatitis B-related cirrhotic liver with serial radiologic images.
authors.affiliation: Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
authors.forename: J M
authors.initials: JM
authors.lastname: Seo
authors.forename: S J
authors.initials: SJ
authors.lastname: Lee
authors.forename: S H
authors.initials: SH
authors.lastname: Kim
authors.forename: C K
authors.initials: CK
authors.lastname: Park
authors.forename: S Y
authors.initials: SY
authors.lastname: Ha
mesh_terms: D018248:Adenoma, Liver Cell / Q000473:pathology*; D000368:Aged; D006528:Carcinoma, Hepatocellular / Q000473:pathology*; D005260:Female; D019694:Hepatitis B, Chronic / Q000150:complications*; D006801:Humans; D008103:Liver Cirrhosis / Q000150:complications*; D008113:Liver Neoplasms / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D016609:Neoplasms, Second Primary / Q000473:pathology*; D014057:Tomography, X-Ray Computed