title: [Association between serum nitric oxide and hypertension among 1453 women in Suzhou].
abstract: OBJECTIVE
  To investigate the association between serum nitric oxide (NO) and hypertension among women in Suzhou.
  
  
  METHODS
  Blood pressure, height, weight and waist circumference (WC) were measured and factors including smoking, alcohol intake, family history of hypertension were investigated and blood glucose, blood lipid, serum NO were tested among 1453 women aged ≥ 30 years who lived in Jinchang district of Suzhou. Association between serum NO and hypertension was analyzed by univariate and multivariate methods.
  
  
  RESULTS
  The mean levels of serum NO in hypertensive and normotensive persons were 28.17 (17.42 - 45.30) µmol/L and 27.56 (17.19 - 44.42) µmol/L, respectively, with no significant difference between the two groups (P > 0.05).
  
  
  RESULTS
  from multivariable logistic regression analysis showed that low serum NO was not associated with hypertension, after adjustment for confounders (OR = 0.979, 95%CI: 0.747 - 1.283). The mean levels of systolic blood pressure/diastolic blood pressure were 130.1/83.3, 128.5/82.7, 129.8/83.2 and 129.1/83.3 mm Hg for whose serum NO level were in the first, second, third and fourth quartile, respectively. The risk of hypertension did not change along with the elevated serum NO levels. Compared to the first quartile of serum NO, the risks of hypertension in the second, third and fourth quartile did not change after adjustment for confounders and OR were 0.988 (0.709 - 1.377), 1.001 (0.720 - 1.390) and 1.077 (0.774 - 1.499), respectively.
  
  
  CONCLUSIONS
  The serum NO level was not associated with hypertension in women in Suzhou.
authors.affiliation: Department of Epidemiology, School of Radiation Medicine and Public Health, Medical College of Soochow University, Suzhou 215123, China.
authors.forename: Shi-hui
authors.initials: SH
authors.lastname: Zhang
authors.forename: Jian-song
authors.initials: JS
authors.lastname: Ding
authors.forename: Yang
authors.initials: Y
authors.lastname: Jiao
authors.forename: Qiu
authors.initials: Q
authors.lastname: Zhang
authors.forename: Hao
authors.initials: H
authors.lastname: Peng
authors.forename: Xin
authors.initials: X
authors.lastname: Gao
authors.forename: Yan-ying
authors.initials: YY
authors.lastname: Xu
authors.forename: Yong-hong
authors.initials: YH
authors.lastname: Zhang
mesh_terms: D000328:Adult; D000368:Aged; D001794:Blood Pressure; D002681:China / Q000453:epidemiology; D005260:Female; D006801:Humans; D006973:Hypertension / Q000453:epidemiology*; D008875:Middle Aged; D009569:Nitric Oxide / Q000097:blood*
chemical_list: D009569:Nitric Oxide