title: Consensus-recommended diagnostic and therapeutic guidelines for drug-resistant epilepsy in Spain (Consenso RATE-España).
abstract: OBJECTIVE
  To ascertain the opinions of an Epilepsy Expert Group and prepare a consensus document on the definition of drug-resistant epilepsy (DRE) according to the International League Against Epilepsy (ILAE) and the different healthcare levels for the patient with epilepsy in Spain.
  
  
  METHODS
  The study was conducted using the Delphi method, by means of successive rounds of questionnaires. A scientific committee prepared a preliminary document and fourteen associated questions, which were sent by e-mail to the panel of experts. They included items related to the concept of DRE, health care levels and the route between these levels for patients with DRE.
  
  
  RESULTS
  A total of 41 experts answered the questionnaire. They agreed regarding the necessity and applicability of the DRE definition according to the ILAE, the need for an expert panel on epilepsy, specialist epilepsy clinics, and clinical epilepsy units stratified depending on the level of activities they carried out. There was moderate consensus on the resources and activity of the clinical units of reference and there was no consensus on the referral of patients who have suffered an epileptic seizure to an epilepsy clinic.
  
  
  CONCLUSIONS
  The expert panel agreed with the definition of DRE according to the ILAE and on referring patients with DRE for a detailed study in an epilepsy clinic or epilepsy clinical unit. They highlighted the need for video-EEG monitoring in the study of patients with DRE and the need to propose other forms of treatment in selected patients.
authors.affiliation: Unidad de Epilepsia, Servicio de Neurología, Hospital Clínico Universitario San Cecilio, Granada, España. jucasan9@gmail.com
authors.forename: J C
authors.initials: JC
authors.lastname: Sánchez-Álvarez
authors.forename: J A
authors.initials: JA
authors.lastname: Mauri-Llerda
authors.forename: A
authors.initials: A
authors.lastname: Gil-Nagel
authors.forename: C
authors.initials: C
authors.lastname: Casas-Fernández
authors.forename: J
authors.initials: J
authors.lastname: Salas-Puig
authors.forename: J
authors.initials: J
authors.lastname: Lahuerta
authors.forename: J
authors.initials: J
authors.lastname: Sancho-Rieger
mesh_terms: D002985:Clinical Protocols; D032921:Consensus; D003697:Delphi Technique; D004351:Drug Resistance; D004569:Electroencephalography; D004827:Epilepsy / Q000175:diagnosis* / Q000188:drug therapy / Q000628:therapy*; D019538:Health Care Surveys; D006801:Humans; D013030:Spain