title: The benefits and risks of stem cell technology.
abstract: The potential impact of stem cell technology on medical and dental practice is vast. Stem cell research will not only provide the foundation for future therapies, but also reveal unique insights into basic disease mechanisms. Therefore, an understanding of stem cell technology will be necessary for clinicians in the future. Herein, we give a basic overview of stem cell biology and therapeutics for the practicing clinician.
authors.affiliation: Center for Molecular Medicine,National Heart, Lung, and Blood Institute, National Institutes of Health, Building 10-CRC, Room 5-3132, Bethesda, MD 20817, USA.
authors.forename: A
authors.initials: A
authors.lastname: Leventhal
authors.forename: G
authors.initials: G
authors.lastname: Chen
authors.forename: A
authors.initials: A
authors.lastname: Negro
authors.forename: M
authors.initials: M
authors.lastname: Boehm
mesh_terms: D020811:Biomedical Technology; D006801:Humans; D044968:Regenerative Medicine; D018570:Risk Assessment; D057905:Stem Cell Research; D013234:Stem Cells / Q000145:classification
references.citation: Br J Haematol. 2002 Nov;119(2):516-24
references.pmid: 12406095
references.citation: Eur Cell Mater. 2008 Jul 31;16:1-9
references.pmid: 18671204
references.citation: J Clin Invest. 2005 Feb;115(2):326-38
references.pmid: 15690083
references.citation: Circ Res. 2011 Mar 18;108(6):648-9
references.pmid: 21415406
references.citation: Curr Hematol Malig Rep. 2010 Apr;5(2):101-8
references.pmid: 20425403
references.citation: J BUON. 2009 Oct-Dec;14(4):551-64
references.pmid: 20148443
references.citation: Cell. 2007 Nov 30;131(5):861-72
references.pmid: 18035408
references.citation: Trends Cell Biol. 2010 Dec;20(12):715-22
references.pmid: 21035344
references.citation: Cell. 2008 Sep 5;134(5):877-86
references.pmid: 18691744
references.citation: J Immunol. 2009 Dec 15;183(12):7787-98
references.pmid: 19923445
references.citation: Eur J Heart Fail. 2007 Aug;9(8):747-53
references.pmid: 17481945
references.citation: J Dent Res. 2002 Aug;81(8):531-5
references.pmid: 12147742
references.citation: J Mol Cell Cardiol. 2008 Oct;45(4):567-81
references.pmid: 18466917
references.citation: PLoS Med. 2009 Feb 17;6(2):e1000029
references.pmid: 19226183
references.citation: Proc Natl Acad Sci U S A. 2009 Aug 11;106(32):13475-80
references.pmid: 19666587
references.citation: Am J Obstet Gynecol. 2010 Mar;202(3):294.e1-294.e11
references.pmid: 20060088
references.citation: Blood. 2001 Jul 1;98(1):6-12
references.pmid: 11418454
references.citation: Circulation. 2009 Oct 13;120(15):1513-23
references.pmid: 19786631
references.citation: Circulation. 2005 Jul 12;112(2):214-23
references.pmid: 15998673
references.citation: Cell. 2006 Aug 25;126(4):663-76
references.pmid: 16904174
references.citation: Liver Int. 2010 Jul;30(6):913-22
references.pmid: 20353420
references.citation: Science. 1998 Nov 6;282(5391):1145-7
references.pmid: 9804556
references.citation: J Cell Biochem. 2011 Feb;112(2):374-80
references.pmid: 21268056
references.citation: Stem Cells. 2010 Sep;28(9):1465-75
references.pmid: 20629173
references.citation: J Card Fail. 2008 Dec;14(10):861-72
references.pmid: 19041051
references.citation: Exp Hematol. 2000 Aug;28(8):875-84
references.pmid: 10989188
references.citation: J Clin Oncol. 2010 Jul 10;28(20):3344-51
references.pmid: 20498405
references.citation: Curr Hematol Malig Rep. 2009 Jul;4(3):139-47
references.pmid: 20425427
references.citation: Science. 2009 Apr 3;324(5923):98-102
references.pmid: 19342590
references.citation: Curr Cardiol Rep. 2010 May;12(3):199-208
references.pmid: 20424962
references.citation: G Ital Dermatol Venereol. 2010 Jun;145(3):345-59
references.pmid: 20461043
references.citation: Blood. 1997 Jul 15;90(2):641-50
references.pmid: 9226164
references.citation: In Vitro Cell Dev Biol Anim. 2010 May;46(5):457-68
references.pmid: 20033791
references.citation: Eur J Haematol. 2003 Nov;71(5):341-50
references.pmid: 14667197
references.citation: Proc Natl Acad Sci U S A. 1989 May;86(10):3828-32
references.pmid: 2566997
references.citation: J Dent Res. 2004 Jul;83(7):518-22
references.pmid: 15218039
references.citation: Oncogene. 2004 Sep 20;23(43):7210-22
references.pmid: 15378081
references.citation: Cell. 2011 Jul 22;146(2):318-31
references.pmid: 21757228
references.citation: Proc Natl Acad Sci U S A. 2010 Mar 2;107(9):4335-40
references.pmid: 20160098
references.citation: Methods Mol Biol. 2007;399:199-213
references.pmid: 18309934
references.citation: Tissue Eng. 2007 Apr;13(4):767-73
references.pmid: 17432951
references.citation: N Engl J Med. 1998 Apr 23;338(17):1186-91
references.pmid: 9554859
references.citation: Recent Results Cancer Res. 2011;185:51-63
references.pmid: 21822819
references.citation: Cell. 2010 Aug 6;142(3):375-86
references.pmid: 20691899
references.citation: Science. 1999 Apr 2;284(5411):143-7
references.pmid: 10102814
references.citation: Circulation. 2003 Mar 11;107(9):1247-9
references.pmid: 12628942
references.citation: J Dent Res. 2009 Sep;88(9):792-806
references.pmid: 19767575
references.citation: Proc Natl Acad Sci U S A. 2005 Aug 9;102(32):11474-9
references.pmid: 16061805
references.citation: N Engl J Med. 2010 Jul 8;363(2):147-55
references.pmid: 20573916
references.citation: Circulation. 2002 Jan 22;105(3):380-6
references.pmid: 11804996
references.citation: Circulation. 2005 Aug 23;112(8):1128-35
references.pmid: 16103243
references.citation: N Engl J Med. 2006 Sep 21;355(12):1210-21
references.pmid: 16990384
references.citation: Cell Stem Cell. 2011 Jun 3;8(6):688-94
references.pmid: 21596650
references.citation: Med Law. 2008 Mar;27(1):147-65
references.pmid: 18592888
references.citation: Circ Res. 2011 Sep 30;109(8):841-7
references.pmid: 21799153
references.citation: Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12991-6
references.pmid: 18728188
references.citation: Nature. 2011 Aug 24;476(7361):409-13
references.pmid: 21866153
references.citation: Haematologica. 2010 Oct;95(10):1754-61
references.pmid: 20494931
references.citation: Bone. 2010 Jun;46(6):1639-51
references.pmid: 20193787
references.citation: Cell. 2011 Aug 5;146(3):359-71
references.pmid: 21816272
references.citation: Science. 2007 Dec 21;318(5858):1917-20
references.pmid: 18029452