title: [The interventions effect-assessment of the workers exposed to N, N-dimethylformamide by percutaneous in a synthetic leather factory].
abstract: OBJECTIVE
  To assess the effects of interventions on synthetic leather workers exposed to N, N-dimethylformamide (DMF) by skin.
  
  
  METHODS
  Twenty-six workers exposed to DMF were recruited. The level of DMF in ambient or handwash solution and N-methylformamide (NMF) in end-shift urine samples were detected before interventions and after interventions for six months.
  
  
  RESULTS
  After interventions the levels of DMF in ambient reduced 52.7% from (63.27 +/- 52.67) mg/m3 to (29.95 +/- 23.79) mg/m3. The levels of NMF in urine samples reduced 17.9% from (2.07 +/- 0.32) mg/g Cr to (1.70 +/- 0.29) mg/g Cr (P < 0.01). The mean level of DMF in handwash solution reduced 53.4% from 0.88 +/- 0.40 mg to 0.41 +/- 0.81 mg.
  
  
  CONCLUSIONS
  This study showed that the multi-intervention measures (engineering control, personal protection and health promotion) should be used for the synthetic leather workers occupationally exposed to DMF.
authors.affiliation: Zhejiang Academy of Medical Sciences, Hangzhou 310013, China.
authors.forename: Ya-Ling
authors.initials: YL
authors.lastname: Qian
authors.forename: Cheng-Min
authors.initials: CM
authors.lastname: Xu
authors.forename: Yan-Yan
authors.initials: YY
authors.lastname: Lu
authors.forename: Yan-Hua
authors.initials: YH
authors.lastname: Wang
authors.forename: Hao
authors.initials: H
authors.lastname: Wu
authors.forename: Xing
authors.initials: X
authors.lastname: Zhang
mesh_terms: D000328:Adult; D004126:Dimethylformamide; D004784:Environmental Monitoring; D006801:Humans; D008297:Male; D008875:Middle Aged; D016273:Occupational Exposure / Q000517:prevention & control*; D011482:Protective Devices; D017132:Workplace; D055815:Young Adult
chemical_list: D004126:Dimethylformamide