title: Efficient synthesis of biazoles by aerobic oxidative homocoupling of azoles catalyzed by a copper(I)/2-pyridonate catalytic system.
abstract: A highly efficient and convenient CuCl/2-pyridonate catalytic system for oxidative homocoupling of azoles affording a biazole product has been developed. With this system, a variety of biazoles have been effectively synthesized in good to excellent yields in the presence of a very small amount of copper catalyst (1.0 mol%). It was feasible to employ air as a green oxidant.
authors.affiliation: Graduate School of Human and Environmental Studies, Kyoto University, Kyoto 606-8501, Japan.
authors.forename: Mingwen
authors.initials: M
authors.lastname: Zhu
authors.forename: Ken-ichi
authors.initials: K
authors.lastname: Fujita
authors.forename: Ryohei
authors.initials: R
authors.lastname: Yamaguchi
mesh_terms: D000388:Air; D001393:Azoles / Q000138:chemical synthesis / Q000737:chemistry*; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D010084:Oxidation-Reduction; D011728:Pyridones / Q000737:chemistry*
chemical_list: D001393:Azoles; D011728:Pyridones; C017679:2-hydroxypyridine; D003300:Copper