title: Identification of latent periodicity in domains of alkaline proteases.
abstract: Internal repeats in protein sequences have wide-ranging implications for the structure and function of proteins. A keen analysis of the repeats in protein sequences may help us to better understand the structural organization of proteins and their evolutionary relations. In this paper, a mathematical method for searching for latent periodicity in protein sequences is developed. Using this method, we identified simple sequence repeats in the alkaline proteases and found that the sequences could show the same periodicity as their tertiary structures. This result may help us to reduce difficulties in the study of the relationship between sequences and their structures.
authors.affiliation: Yellow Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Qingdao, Shandong.
authors.forename: Xiaofeng
authors.initials: X
authors.lastname: Ji
authors.forename: Jun
authors.initials: J
authors.lastname: Sheng
authors.forename: Fang
authors.initials: F
authors.lastname: Wang
authors.forename: Suzhen
authors.initials: S
authors.lastname: Zhang
authors.forename: Jianhua
authors.initials: J
authors.lastname: Hao
authors.forename: Haiying
authors.initials: H
authors.lastname: Wang
authors.forename: Mi
authors.initials: M
authors.lastname: Sun
mesh_terms: D000595:Amino Acid Sequence; D001419:Bacteria / Q000737:chemistry / Q000201:enzymology* / Q000235:genetics; D001426:Bacterial Proteins / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism; D010450:Endopeptidases / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism; D008958:Models, Molecular; D008969:Molecular Sequence Data; D017434:Protein Structure, Tertiary; D012091:Repetitive Sequences, Nucleic Acid; D016415:Sequence Alignment
chemical_list: D001426:Bacterial Proteins; D010450:Endopeptidases; C087822:alkaline protease