title: Validation of three-dimensional echocardiography for quantification of aortic root geometry: comparison with multi-detector computed tomography.
abstract: BACKGROUND
  Three-dimensional (3D) echocardiography has been reported to be valuable for evaluating the geometry of cardiac chambers. We validated the accuracy of 3D transthoracic echocardiography for quantifying aortic root geometry in comparison with cardiac multi-detector computed tomography (MDCT).
  
  
  METHODS
  Twenty-three patients who underwent cardiac MDCT and showed normal left ventricular ejection fraction (> 55%), as assessed by 2-dimensional transthoracic echocardiography, were enrolled (12 male, mean 53 ± 9 years). We defined the aortic root volume as the volume from the aortic annulus to the sinotubular junction. The aortic root volume at end-diastole measured by both cardiac MDCT and 3D echocardiography was assessed.
  
  
  RESULTS
  The cross-sectional area of the aortic root was asymmetric. At the annulus level, the cross-sectional area showed asymmetric triangle. From the aortic annulus to the most dilated point of the sinus of Valsalva, the asymmetric triangular shape was maintained. From the most dilated point of the sinus of Valsalva to the sinotubular junction, the cross-sectional shape of the aortic root changed to oval. The average aortic root volumes measured by 3D echocardiography (ARV-3DE) were 13.6 ± 4.8 mL at end-diastole and 14.1 ± 5.3 mL at end-systole, respectively. The average aortic root volume measured by MDCT at end-diastole (ARV-CT) was 14.1 ± 5.7 mL. At end-diastole, the ARV-3DE correlated well with the ARV-CT (R(2) = 0.926, difference = 0.5 ± 1.7 mL), and the two methods were in excellent agreement (the percent difference was 0%).
  
  
  CONCLUSIONS
  Our results demonstrate both the feasibility and accuracy of 3D echocardiography for the clinical assessment of the geometry of the aortic root.
authors.affiliation: Department of Cardiology, Ajou University School of Medicine, Suwon, Korea.
authors.forename: Jin-Sun
authors.initials: JS
authors.lastname: Park
authors.forename: Yong-Woo
authors.initials: YW
authors.lastname: Choi
authors.forename: Jeoung-Sook
authors.initials: JS
authors.lastname: Shin
authors.forename: Hyoung-Mo
authors.initials: HM
authors.lastname: Yang
authors.forename: Hong-Seok
authors.initials: HS
authors.lastname: Lim
authors.forename: Byoung-Joo
authors.initials: BJ
authors.lastname: Choi
authors.forename: So-Yeon
authors.initials: SY
authors.lastname: Choi
authors.forename: Myeong-Ho
authors.initials: MH
authors.lastname: Yoon
authors.forename: Gyo-Seung
authors.initials: GS
authors.lastname: Hwang
authors.forename: Seung-Jea
authors.initials: SJ
authors.lastname: Tahk
authors.forename: Joon-Han
authors.initials: JH
authors.lastname: Shin
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