title: Kinetics of nanochain formation in a simplified model of amelogenin biomacromolecules.
abstract: We show that the kinetics of nanochain formation of amelogenin molecules is well described by a combination of translational and rotational diffusion of a simplified anisotropic bipolar model consisting of hydrophobic spherical colloid particles and a point charge located on each particle surface. The colloid particles interact via a standard depletion attraction whereas the point charges interact through a screened Coulomb repulsion. We study the kinetics via a Brownian dynamics simulation of both translational and rotational motions and show that the anisotropy brought in by the charge dramatically affects the kinetic pathway of cluster formation and our simple model captures the main features of the experimental observations.
authors.affiliation: Department of Physics, Lehigh University, Bethlehem, Pennsylvania, USA. wel208@lehigh.edu
authors.forename: Wei
authors.initials: W
authors.lastname: Li
authors.forename: Ya
authors.initials: Y
authors.lastname: Liu
authors.forename: Toni
authors.initials: T
authors.lastname: Perez
authors.forename: J D
authors.initials: JD
authors.lastname: Gunton
authors.forename: C M
authors.initials: CM
authors.lastname: Sorensen
authors.forename: A
authors.initials: A
authors.lastname: Chakrabarti
mesh_terms: D053523:Amelogenin / Q000737:chemistry*; D003102:Colloids / Q000737:chemistry; D007700:Kinetics; D046911:Macromolecular Substances / Q000737:chemistry*; D008958:Models, Molecular; D053758:Nanoparticles / Q000737:chemistry*; D013997:Time Factors
chemical_list: D053523:Amelogenin; D003102:Colloids; D046911:Macromolecular Substances
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