title: Laparoscopic lymphatic roadmapping with blue dye and radioisotope in colon cancer.
abstract: Lymphatic mapping (LM) and sentinel lymph node (SLN) identification by blue dye in colon cancer is a procedure feasible during minimally invasive surgery, with good specificity, but still a low sensitivity (78% in our series). These results are in accordance with the literature and have limited more widespread diffusion of the method, both as a tool for upstaging and more controversially, as a potential roadmap to a tailored lymphadenectomy. It is possible to improve the results of LM with careful selection of patients and by the use of an intraoperative gamma camera. The preliminary results of intra-operative lymphoscintigraphy are promising in a well-selected small group of patients, with high levels of sensitivity and specificity. If these results are confirmed in further prospective analyses, it may be possible to undertake selected, tailored lymphadenectomy.
authors.affiliation: Unit of Minimally-Invasive Surgery, European Institute of Oncology, Milano, Italy. paolo.bianchi@ieo.it
authors.forename: P P
authors.initials: PP
authors.lastname: Bianchi
authors.forename: W
authors.initials: W
authors.lastname: Petz
authors.forename: L
authors.initials: L
authors.lastname: Casali
mesh_terms: D000368:Aged; D003110:Colonic Neoplasms / Q000473:pathology*; D004396:Coloring Agents; D005260:Female; D015902:Gamma Cameras; D006801:Humans; D007430:Intraoperative Care; D010535:Laparoscopy; D008198:Lymph Nodes / Q000000981:diagnostic imaging / Q000473:pathology; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011237:Predictive Value of Tests; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D012394:Rosaniline Dyes; D021701:Sentinel Lymph Node Biopsy / Q000379:methods*; D013668:Technetium Tc 99m Aggregated Albumin
chemical_list: D004396:Coloring Agents; D019275:Radiopharmaceuticals; D012394:Rosaniline Dyes; D013668:Technetium Tc 99m Aggregated Albumin; C083602:technetium Tc 99m nanocolloid; C008769:sulfan blue