title: Relationship between the level of antibodies in bulk tank milk and the within-herd seroprevalence of Coxiella burnetii in cows.
abstract: The relationship between the level of antibodies in bulk tank milk (BTM) and the within-herd seroprevalence of Coxiella burnetii in cows was assessed. Blood from milking cows and BTM were sampled in 55 infected herds and tested using commercial enzyme-linked immunosorbent assay (ELISA) kits. The relationship between antibody levels and WHP, which was quantified using a general linear model, was only moderate (R(2)=0·15). Nevertheless, the lowest antibody level in BTM was associated with the lowest mean within-herd prevalence. The present finding indicates that ELISA applied to BTM could identify infected herds with quite low within-herd seroprevalence. For such herds, the vaccination of dairy cows as well as nulliparous heifers using a phase I vaccine could effectively prevent C. burnetii shedding.
authors.affiliation: ONIRIS, UMR 1300 Bio-Agression, Epidémiologie et Analyse de Risque, Nantes, F-44307, France. anne-frieda.taurel@oniris-nantes.fr
authors.forename: A-F
authors.initials: AF
authors.lastname: Taurel
authors.forename: R
authors.initials: R
authors.lastname: Guatteo
authors.forename: A
authors.initials: A
authors.lastname: Joly
authors.forename: F
authors.initials: F
authors.lastname: Beaudeau
mesh_terms: D000818:Animals; D000907:Antibodies, Bacterial / Q000032:analysis / Q000097:blood; D002417:Cattle; D002418:Cattle Diseases / Q000453:epidemiology* / Q000276:immunology / Q000382:microbiology; D016997:Coxiella burnetii / Q000276:immunology / Q000302:isolation & purification*; D003612:Dairying; D004797:Enzyme-Linked Immunosorbent Assay / Q000662:veterinary; D005260:Female; D005602:France / Q000453:epidemiology; D016014:Linear Models; D008892:Milk / Q000737:chemistry / Q000276:immunology; D015995:Prevalence; D011778:Q Fever / Q000453:epidemiology / Q000276:immunology / Q000382:microbiology / Q000662:veterinary*; D012621:Seasons; D016036:Seroepidemiologic Studies
chemical_list: D000907:Antibodies, Bacterial