title: Management of sulfur mustard-induced chronic pruritus: a review of clinical trials.
abstract: Skin is among the most heavily damaged organs upon sulfur mustard (SM) exposure. Chronic complications due to SM-induced dermatotoxicity are quite frequent among intoxicated patients. Nevertheless, the exact pathophysiology of SM-induced chronic cutaneous complications has not been well clarified yet. The present review highlights clinically important findings on the management of SM-induced chronic skin complications with a particular focus on pruritus as the most prevalent symptom that has a significant impact on patients' quality of life. Some methodological pitfalls that implicate the validity of the trials have also been identified.
authors.affiliation: Chemical Injuries Research Center, Baquiyatallah University of Medical Sciences, Tehran, Iran. yunespanahi@yahoo.com
authors.forename: Yunes
authors.initials: Y
authors.lastname: Panahi
authors.forename: Amir
authors.initials: A
authors.lastname: Sarayani
authors.forename: Fatemeh
authors.initials: F
authors.lastname: Beiraghdar
authors.forename: Mojtaba
authors.initials: M
authors.lastname: Amiri
authors.forename: Seyed Masoud
authors.initials: SM
authors.lastname: Davoudi
authors.forename: Amirhossein
authors.initials: A
authors.lastname: Sahebkar
mesh_terms: D002908:Chronic Disease; D002986:Clinical Trials as Topic; D006801:Humans; D009151:Mustard Gas / Q000633:toxicity*; D011537:Pruritus / Q000139:chemically induced*
chemical_list: D009151:Mustard Gas