title: Do elderly patients with metastatic cancer have worse quality of life scores?
abstract: OBJECTIVE
  The purpose of this study is to compare self-reported quality of life (QOL) scores in old and young patients with metastatic cancer using the European Organization for Research and Treatment of Cancer (EORTC) QLQ-C15-PAL questionnaire.
  
  
  METHODS
  Patients receiving palliative radiotherapy (RT) for bone metastases and brain metastases completed the QLQ-C15-PAL questionnaire prior to treatment. Using multiple linear regression analysis, a parametric test, the QLQ-C15-PAL scores were compared using 65 and 70 years as cutoff ages.
  
  
  RESULTS
  A total of 340 patients were referred for palliative RT for bone metastases (n = 190) or brain metastases (n = 150). Physical functioning and appetite were worse in the older group using either 65 or 70 years as the cutoff age. Age-related differences in the QLQ-C15-PAL scores varied as a function of age cutoff used and location of metastatic site irradiated.
  
  
  CONCLUSIONS
  Based on the (EORTC) QLQ-C15-PAL, elderly advanced cancer patients have a different QOL profile. Similar observations have been reported with the (EORTC) QLQ-C30 questionnaire.
authors.affiliation: Rapid Response Radiotherapy Program, Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada.
authors.forename: Kaitlin
authors.initials: K
authors.lastname: Koo
authors.forename: Liang
authors.initials: L
authors.lastname: Zeng
authors.forename: Emily
authors.initials: E
authors.lastname: Chen
authors.forename: Liying
authors.initials: L
authors.lastname: Zhang
authors.forename: Shaelyn
authors.initials: S
authors.lastname: Culleton
authors.forename: Kristopher
authors.initials: K
authors.lastname: Dennis
authors.forename: Amanda
authors.initials: A
authors.lastname: Caissie
authors.forename: Janet
authors.initials: J
authors.lastname: Nguyen
authors.forename: Lori
authors.initials: L
authors.lastname: Holden
authors.forename: Florencia
authors.initials: F
authors.lastname: Jon
authors.forename: May
authors.initials: M
authors.lastname: Tsao
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Barnes
authors.forename: Cyril
authors.initials: C
authors.lastname: Danjoux
authors.forename: Arjun
authors.initials: A
authors.lastname: Sahgal
authors.forename: Edward
authors.initials: E
authors.lastname: Chow
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001859:Bone Neoplasms / Q000532:radiotherapy / Q000556:secondary*; D001932:Brain Neoplasms / Q000532:radiotherapy* / Q000556:secondary*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009864:Ontario; D011788:Quality of Life; D012044:Regression Analysis; D057566:Self Report; D011795:Surveys and Questionnaires; D055815:Young Adult
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