title: Free vascularized flaps for reconstruction of the mandible: complications, success, and dental rehabilitation.
abstract: OBJECTIVE
  To evaluate complications and success of mandibular reconstruction with free fibula flaps, iliac crest flaps, and forearm flaps with reconstruction plates and to evaluate dental rehabilitation after these reconstructions.
  
  
  METHODS
  Eighty-three patients with segmental mandibular defects were included. Correlation analyses were used to determine the relationship between reconstruction type and clinical parameters with recipient-site complications and success. The dental rehabilitation was evaluated in successfully reconstructed survivors.
  
  
  RESULTS
  Multivariate analyses showed significant correlations between flap type and success (P < .0001). Of the patients, 51 (61%) were alive 2 years after the reconstruction. Mandibular reconstruction with a free forearm flap and reconstruction plate was associated with higher complication rates at the recipient site and higher failure rates compared with reconstruction with free vascularized bone flaps. Of the 32 successfully reconstructed survivors, 14 (44%) had a complete dental rehabilitation, of which 10 had dental implants and 4 did not. Only 6 (29%) of the edentulous survivors ultimately had an implant-supported prosthesis.
  
  
  CONCLUSIONS
  Reconstruction of the mandible with a free vascularized bone flap is superior to reconstruction with a free forearm flap with a reconstruction plate. Complete dental rehabilitation was reached in fewer than half of the surviving patients.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Prosthodontics and Special Dental Care, University Medical Center Utrecht, Utrecht, The Netherlands. j.t.m.vangemert@umcutrecht.nl
authors.forename: Johannes T M
authors.initials: JT
authors.lastname: van Gemert
authors.forename: Robert J J
authors.initials: RJ
authors.lastname: van Es
authors.forename: Antoine J W P
authors.initials: AJ
authors.lastname: Rosenberg
authors.forename: Andries
authors.initials: A
authors.lastname: van der Bilt
authors.forename: Ron
authors.initials: R
authors.lastname: Koole
authors.forename: Ellen M
authors.initials: EM
authors.lastname: Van Cann
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001860:Bone Plates; D016025:Bone Transplantation / Q000379:methods; D002294:Carcinoma, Squamous Cell / Q000534:rehabilitation / Q000601:surgery; D003758:Dental Implantation, Endosseous; D015921:Dental Implants; D019094:Dental Prosthesis, Implant-Supported; D005260:Female; D005500:Follow-Up Studies; D058752:Free Tissue Flaps / Q000145:classification*; D006085:Graft Survival; D006801:Humans; D008297:Male; D008334:Mandible / Q000601:surgery*; D008338:Mandibular Injuries / Q000534:rehabilitation / Q000601:surgery; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000534:rehabilitation / Q000601:surgery; D010027:Osteotomy / Q000379:methods; D011183:Postoperative Complications; D019651:Plastic Surgery Procedures / Q000379:methods*; D012189:Retrospective Studies; D015996:Survival Rate; D020858:Tissue and Organ Harvesting / Q000379:methods; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D015921:Dental Implants