title: [Central nervous system involvement in systemic sclerosis].
abstract: Systemic sclerosis is a connective disease usually known to spare the central nervous system. This has been much debated by recent imaging studies. We report a 56-year-old woman followed-up for systemic sclerosis since 2005. Four years later, she presented with cerebellar and pyramidal syndrome. Magnetic resonance imaging showed signs of cerebral vasculitis. The patient was treated by corticosteroids and cyclophosphamide pulses followed by azathioprine for maintenance therapy. Clinical and radiological outcomes were favourable. In patients with systemic sclerosis and neurological symptoms, abnormalities in the cerebral magnetic resonance imaging may, in the absence of another obvious etiology, indicate a central nervous system involvement associated with this systemic disorder.
authors.affiliation: Service de médecine interne, hôpital militaire de Tunis, Montfleury 1008 Tunis, Tunisie. faida1977@yahoo.fr
authors.forename: F
authors.initials: F
authors.lastname: Ajili
authors.forename: A
authors.initials: A
authors.lastname: Mersni
authors.forename: L
authors.initials: L
authors.lastname: Métoui
authors.forename: I
authors.initials: I
authors.lastname: Gharsallah
authors.forename: J
authors.initials: J
authors.lastname: Laabidi
authors.forename: R
authors.initials: R
authors.lastname: Battikh
authors.forename: F
authors.initials: F
authors.lastname: Msadak
authors.forename: B
authors.initials: B
authors.lastname: Louzir
authors.forename: N
authors.initials: N
authors.lastname: Ben Abdelhafidh
authors.forename: S
authors.initials: S
authors.lastname: Othmani
mesh_terms: D002490:Central Nervous System / Q000000981:diagnostic imaging / Q000473:pathology*; D002493:Central Nervous System Diseases / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology; D005260:Female; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D008875:Middle Aged; D011859:Radiography; D012595:Scleroderma, Systemic / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology