title: Pseudomonas aeruginosa in cystic fibrosis: pathogenesis and new treatments.
abstract: Pseudomonas aeruginosa is the most problematic organism in patients with cystic fibrosis. This article reviews its pathogenic mechanisms, with particular relevance to the pathophysiology of the cystic fibrosis airway, and recent advances in therapeutic approaches.
authors.affiliation: Centre for Peadiatrics, Blizand Institute of cell and Molecular Science, Barts and The London School of Medicine and Dentistry, London.
authors.forename: Rossa E
authors.initials: RE
authors.lastname: Brugha
authors.forename: Jane C
authors.initials: JC
authors.lastname: Davies
mesh_terms: D018441:Biofilms / Q000254:growth & development; D003550:Cystic Fibrosis / Q000150:complications* / Q000382:microbiology; D024881:Drug Resistance, Bacterial; D006801:Humans; D011552:Pseudomonas Infections / Q000188:drug therapy* / Q000209:etiology*; D011550:Pseudomonas aeruginosa / Q000254:growth & development*