title: Prevalence of risk factors of cardiovascular diseases in men with erectile dysfunction. Are they as frequent as we believe?
abstract: OBJECTIVE
  Vascular erectile dysfunction (ED) predicts future development of cardiovascular diseases (CVD). We performed a study in men seeking consultant medical advice regarding vascular ED for the first time without a history of cardiovascular disease, diabetes mellitus or renal insufficiency. Our goal was to evaluate the prevalence of CVD risk factors in this cohort of patients. Furthermore, we assessed the prevalence of asymptomatic subclinical atherosclerosis.
  
  
  METHODS
  All study subjects underwent a thorough physical examination including anthropometric measurements. Laboratory analyses comprising assessment of lipid spectrum, liver and kidney function tests, glycaemia and glycated haemoglobin were measured using automated analysers. Intima-media thickness of carotid arteries was measured using SONOS machine and ankle-brachial index using a mini-duplex device. CVD risk was calculated by standard SCORE charts. Chi-square test, t-test and ANOVA were used for statistical analysis.
  
  
  RESULTS
  We examined 35 men, average age 46.5 ± 9.9 years. Six (17.1%) had a positive family history of CVD, 19 (54.3%) had dyslipidemia, 10 (28.6%) were obese, 9 (25.7%) were active smokers, and 14 (40.0%) had arterial hypertension. Eighteen (51.4%) subjects had subclinical atherosclerosis as determined by ABI and CIMT assessment.
  
  
  CONCLUSIONS
  Patients with vascular erectile dysfunction have similar prevalence of CVD risk factors to general population.
authors.affiliation: 3rd Department of Internal Medicine, 1st Faculty of Medicine, Charles University Prague, Czech Republic. martina.prusikova@seznam.cz
authors.forename: Martina
authors.initials: M
authors.lastname: Prusikova
authors.forename: Michal
authors.initials: M
authors.lastname: Vrablik
authors.forename: Libor
authors.initials: L
authors.lastname: Zamecnik
authors.forename: Eva
authors.initials: E
authors.lastname: Horova
authors.forename: Vera
authors.initials: V
authors.lastname: Lanska
authors.forename: Richard
authors.initials: R
authors.lastname: Ceska
mesh_terms: D000328:Adult; D000368:Aged; D000886:Anthropometry; D050197:Atherosclerosis / Q000150:complications / Q000453:epidemiology; D001786:Blood Glucose / Q000378:metabolism; D001794:Blood Pressure / Q000502:physiology; D002318:Cardiovascular Diseases / Q000150:complications* / Q000453:epidemiology*; D008078:Cholesterol, LDL / Q000097:blood; D050171:Dyslipidemias / Q000150:complications; D007172:Erectile Dysfunction / Q000150:complications* / Q000453:epidemiology*; D006442:Glycated Hemoglobin / Q000032:analysis; D006801:Humans; D007677:Kidney Function Tests; D008111:Liver Function Tests; D008297:Male; D008875:Middle Aged; D012039:Regional Blood Flow / Q000502:physiology; D012307:Risk Factors; D012907:Smoking / Q000453:epidemiology
chemical_list: D001786:Blood Glucose; D008078:Cholesterol, LDL; D006442:Glycated Hemoglobin