title: Trigeminal artery: a review of normal and pathological features.
abstract: OBJECTIVE
  Carotid-vertebrobasilar anastomoses-the trigeminal, otic, hypoglossal, and proatlantal intersegmental arteries-serve as transitory channels between primitive internal carotid arteries and bilateral longitudinal neural arterial plexus, which is the precursor of future basilar artery, when the human embryo reaches about 4-mm length.
  
  
  METHODS
  Normal and/or abnormal morphofunctional aspects of the prenatal and postnatal forms of the trigeminal artery are described according to personal and literature data. Many arteries of similar origin and course are also noted in the differential diagnosis of the trigeminal artery.
  
  
  CONCLUSIONS
  The persistent primitive trigeminal artery, as the most commonly carotid-vertebrobasilar anastomosis, has a reported incidence of 0.03-2.2% in the literature. There is female sex predilection, and it may be discovered in patients of any age, on either side, and in association with many vascular variants. Although the significance of persistent primitive trigeminal artery regarding the development of an aneurysm or association with another pathological condition may not be clear, its (ab)normal morphology is the inspiration for anatomists, especially for neurosurgeons, before planning diagnostic and therapeutic procedures.
authors.affiliation: Department of Anatomy, Faculty of Medicine, University of Niš, Blvd. Dr Zoran Đinđić 81, 18000 Niš, Serbia. likica@medfak.ni.ac.rs
authors.forename: Ljiljana
authors.initials: L
authors.lastname: Vasović
authors.forename: Ivan
authors.initials: I
authors.lastname: Jovanović
authors.forename: Slađana
authors.initials: S
authors.lastname: Ugrenović
authors.forename: Slobodan
authors.initials: S
authors.lastname: Vlajković
authors.forename: Predrag
authors.initials: P
authors.lastname: Jovanović
authors.forename: Vesna
authors.initials: V
authors.lastname: Stojanović
mesh_terms: D001488:Basilar Artery / Q000033:anatomy & histology*; D001921:Brain / Q000098:blood supply*; D002343:Carotid Artery, Internal / Q000033:anatomy & histology*; D005260:Female; D006801:Humans; D008297:Male; D014711:Vertebral Artery / Q000033:anatomy & histology*
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