title: Electrochemical imprinted sensor for determination of oleanic acid based on poly (sodium 4-styrenesulfonate-co-acrylic acid)-grafted multi-walled carbon nanotubes-chitosan and cobalt hexacyanoferrate nanoparticles.
abstract: A novel sensitive and selective imprinted electrochemical sensor for the determination of oleanic acid was constructed on a carbon electrode by stepwise modification of functional multi-walled carbon nanotubes, cobalt hexacyanoferrate nanoparticles and a thin imprinted sol-gel film. The fabrication of a homogeneous porous poly (sodium 4-styrenesulfonate-co-acrylic acid)-grafted multi-walled carbon nanotubes/SiO(2)-chitosan nanocomposite film was conducted by controllable electrodeposition technology. The surface morphologies of the modified electrodes were characterized by scanning electron microscope. The performance of the imprinted sensor was investigated by cyclic voltammetry, square wave voltammetry and electrochemical impedance spectroscopy in detail. The imprinted sensor displayed high sensitivity and selectivity towards oleanic acid. A linear relationship between the sensor response signal and the logarithm of oleanic acid concentrations ranging from 1.0×10(-8) to 1.0×10(-3) mol L(-1) was obtained with a detection limit of 2.0×10(-9) mol L(-1). It was applied to the determination of oleanic acid in real capsule samples successfully.
authors.affiliation: College of Chemistry and Chemical Engineering, Jishou University, Hunan 416000, PR China.
authors.forename: Yufang
authors.initials: Y
authors.lastname: Hu
authors.forename: Zhaohui
authors.initials: Z
authors.lastname: Zhang
authors.forename: Jiaxing
authors.initials: J
authors.lastname: Li
authors.forename: Huabin
authors.initials: H
authors.lastname: Zhang
authors.forename: Lijuan
authors.initials: L
authors.lastname: Luo
authors.forename: Shouzhuo
authors.initials: S
authors.lastname: Yao
mesh_terms: D000179:Acrylates / Q000737:chemistry*; D015374:Biosensing Techniques / Q000295:instrumentation*; D048271:Chitosan / Q000737:chemistry*; D003217:Conductometry / Q000295:instrumentation*; D004595:Electroplating / Q000379:methods; D004867:Equipment Design; D019544:Equipment Failure Analysis; D005295:Ferrocyanides / Q000737:chemistry*; D037742:Nanotubes, Carbon / Q000737:chemistry*; D009828:Oleanolic Acid / Q000032:analysis*; D011137:Polystyrenes / Q000737:chemistry*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
chemical_list: D000179:Acrylates; D005295:Ferrocyanides; D037742:Nanotubes, Carbon; D011137:Polystyrenes; C116383:ferrocyn; C520172:poly(acrylic acid)-b-poly(methyl acrylate)-b-polystyrene; D009828:Oleanolic Acid; D048271:Chitosan