title: 2-Chloro-methyl-1-methyl-1,3-benzimidazole.
abstract: The title compound, C(9)H(9)ClN(2), was prepared from the reaction of N-methyl-benzene-1,2-diamine and 2-chloro-acetic acid in boiling 6 M hydro-chloric acid. The benzimidazole unit is approximately planar, the largest deviation from the mean plane being 0.008 (1) Å. The Cl atom is displaced by 1.667 (2) Å from this plane. The methyl group is statistically disordered with equal occupancy.
authors.forename: Jie
authors.initials: J
authors.lastname: Han
authors.forename: Jun
authors.initials: J
authors.lastname: Zhang
authors.forename: Qi
authors.initials: Q
authors.lastname: Yang
authors.forename: Ming-Gao
authors.initials: MG
authors.lastname: Zhao
authors.forename: Guang
authors.initials: G
authors.lastname: Fan
references.citation: Eur J Med Chem. 2010 Jul;45(7):2949-56
references.pmid: 20399544
references.citation: Chem Rev. 2003 Mar;103(3):893-930
references.pmid: 12630855
references.citation: Bioorg Med Chem Lett. 2003 Jul 21;13(14):2291-5
references.pmid: 12824020
references.citation: Acta Crystallogr B. 2002 Jun;58(Pt 3 Pt 1):380-8
references.pmid: 12037359
references.citation: J Med Chem. 1998 Apr 9;41(8):1242-51
references.pmid: 9575044
references.citation: J Med Chem. 1997 Dec 19;40(26):4199-207
references.pmid: 9435891
references.citation: Jpn J Pharmacol. 1994 Feb;64(2):115-24
references.pmid: 8028228
references.citation: J Med Chem. 1998 Apr 9;41(8):1252-62
references.pmid: 9548815
references.citation: Acta Crystallogr A. 2008 Jan;64(Pt 1):112-22
references.pmid: 18156677
references.citation: Anticancer Drugs. 2010 Jan;21(1):33-42
references.pmid: 19786863