title: Extranodal NK/T-cell lymphoma, nasal type extensively involving the bone marrow.
abstract: Extranodal NK/T-cell lymphoma, nasal type, is an aggressive EBV-associated lymphoma that mainly involves the nasal cavity but has also been reported to involve other extranodal sites without nasal involvement. In contrast to aggressive NK cell leukemia (a marrow-based aggressive leukemia of NK-cell origin); extensive bone marrow and blood involvement is extremely uncommon by nasal type NK/T lymphoma. We report a patient with extranodal NK/T-cell lymphoma, nasal type that developed extensive bone marrow involvement during the course of her disease with some overlapping features with aggressive NK-cell leukemia.
authors.affiliation: Department of Pathology & Laboratory Medicine, University of California, Irvine (UCI), USA.
authors.forename: Sherif A
authors.initials: SA
authors.lastname: Rezk
authors.forename: Qin
authors.initials: Q
authors.lastname: Huang
mesh_terms: D014408:Biomarkers, Tumor / Q000032:analysis; D001706:Biopsy; D001853:Bone Marrow / Q000737:chemistry / Q000473:pathology*; D001856:Bone Marrow Examination; D005260:Female; D006801:Humans; D007621:Karyotyping; D054391:Lymphoma, Extranodal NK-T-Cell / Q000737:chemistry / Q000235:genetics / Q000473:pathology* / Q000628:therapy; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009669:Nose Neoplasms / Q000737:chemistry / Q000235:genetics / Q000473:pathology* / Q000628:therapy
chemical_list: D014408:Biomarkers, Tumor
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