title: Accuracy of GFR predictive equations in renal transplantation: validation of a new turbidimetric cystatin C assay on Architect c8000.
abstract: OBJECTIVE
  To evaluate the Sentinel-PETIA cystatin C on Architect c8000 analyzer.
  
  
  METHODS
  We assessed analytical performances and clinical relevance by comparison with a reference isotopic method in kidney transplant recipients.
  
  
  RESULTS
  This assay exhibited reliable precision and was close to the non standardized Siemens-PENIA method. All tested equations allowed reliable assessment of GFR.
  
  
  CONCLUSIONS
  Cystatin C improved GFR determination at the critical level of 60 mL/min/1.73 m². New formulas might be necessary after IFCC standardization.
authors.affiliation: Department of Biochemistry, University of Montpellier 1, Montpellier, France.
authors.forename: A S
authors.initials: AS
authors.lastname: Bargnoux
authors.forename: A C
authors.initials: AC
authors.lastname: Servel
authors.forename: L
authors.initials: L
authors.lastname: Piéroni
authors.forename: A M
authors.initials: AM
authors.lastname: Dupuy
authors.forename: S
authors.initials: S
authors.lastname: Badiou
authors.forename: V
authors.initials: V
authors.lastname: Garrigue
authors.forename: G
authors.initials: G
authors.lastname: Mourad
authors.forename: J P
authors.initials: JP
authors.lastname: Cristol
mesh_terms: D000328:Adult; D000368:Aged; D002138:Calibration; D019411:Clinical Laboratory Techniques; D003404:Creatinine / Q000097:blood; D055316:Cystatin C / Q000097:blood*; D005260:Female; D005919:Glomerular Filtration Rate; D006801:Humans; D007676:Kidney Failure, Chronic / Q000628:therapy; D007677:Kidney Function Tests; D016030:Kidney Transplantation / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009391:Nephelometry and Turbidimetry / Q000379:methods*; D010316:Particle Size; D011237:Predictive Value of Tests; D012015:Reference Standards; D015203:Reproducibility of Results
chemical_list: D055316:Cystatin C; D003404:Creatinine