title: Hepatitis B and C among women with illegal social behavior in Isfahan, Iran: Seroprevalence and associated factors.
abstract: BACKGROUND
  In Iran, there is limited evidence on the prevalence of hepatitis B and C viruses (HBV and HCV) among females who engage in illegal sexual behavior.
  
  
  OBJECTIVE
  To determine the prevalence of HBV and HCV infections and their associated factors in this population in Isfahan-Iran.
  
  
  METHODS
  In this cross-sectional study, 100 females who engaged in illegal sexual behavior during 2009-2010 in Isfahan were recruited from welfare to the DIC for women, and referrals were made among those who knew others who engaged in prostitution. Markers for HBV and HCV-Ab were measured by ELISA, and recombinant immunoblot assay was used for confirmation of HCV infection. Also, a questionnaire on demographics and prostitution-associated risk data in a face-to-face interview was completed for each participant. Chi-square and multivariate logistic regression models were used for data analysis.
  
  
  RESULTS
  Of the 100 samples collected, 91 were sufficient for testing. The mean age and time spent in sex work were 30.84 ± 9.34 years and 36 ± 28.5 months, respectively. HBsAg was detected in 1 (1.1%), anti-HBc in 4 (4.4%), anti-HBs in 60 (65.9%), and HCV Ab in 9 (9.9%) subjects. The evidence of vaccination was seen in 54 subjects (59.3%). There were no significant differences in the prevalence of HBV or HCV infection by estimated risk factors, and there was no independent risk factor for these infections.
  
  
  CONCLUSIONS
  The high prevalence of HCV infection in this study indicates the need to implement preventive interventions for female sex workers and, perhaps more importantly, to involve their male clients.
authors.affiliation: Infectious Diseases and Tropical Medicine Research Center, Isfahan University of Medical Sciences, Isfahan, IR Iran.
authors.forename: Nazila
authors.initials: N
authors.lastname: Kassaian
authors.forename: Behrooz
authors.initials: B
authors.lastname: Ataei
authors.forename: Majid
authors.initials: M
authors.lastname: Yaran
authors.forename: Anahita
authors.initials: A
authors.lastname: Babak
authors.forename: Parisa
authors.initials: P
authors.lastname: Shoaei
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