title: Pharmaceutical interventions on prescription problems in a Danish pharmacy setting.
abstract: BACKGROUND
  International studies regarding pharmacists' interventions towards prescription problems produce highly variable results. The only peer-reviewed study in a Danish setting estimated an intervention rate of 2.3 per 1,000 prescriptions. With the introduction of a new tool for registration, we hypothesized that a better estimate could be obtained.
  
  
  OBJECTIVE
  We aimed to produce an up-to-date estimate of the extent and type of pharmacists' interventions towards prescription problems in a Danish pharmacy setting
  
  
  METHODS
  The study was conducted at Copenhagen Sønderbro Pharmacy, a large urban 24-hour pharmacy.
  
  
  METHODS
  Data were collected prospectively through an electronic form. All interventions were primarily classified as either clinical or administrative in nature, and further classified in a number of pre-determined subcategories. Furthermore, information about age, sex, time of day, the wording of the prescription, the performed intervention, the person performing the intervention and the type of prescriber were recorded. All entries were manually validated by a study pharmacist.
  
  
  METHODS
  The intervention rate, given as the number of interventions per 1,000 prescriptions.
  
  
  RESULTS
  We found 599 validated interventions. Thirty-two percent of the interventions were clinical and 68% administrative by nature. Fifty-one percent of the administrative and 35% of the clinical interventions were regarding antibiotics. In the study period, a total of 55,522 prescriptions were filled out together with 3,069 dose-dispensing packages, giving a rate of 10.2 (9.4-11.1) interventions per 1,000 prescriptions.
  
  
  CONCLUSIONS
  We found an intervention rate substantially higher than reported in previous Danish studies.
authors.affiliation: Research Unit of Clinical Pharmacology, University of Southern Denmark, JB Winsløwsvej 19, 2, 5000, Odense C, Denmark. apottegaard@health.sdu.dk
authors.forename: Anton
authors.initials: A
authors.lastname: Pottegård
authors.forename: Jesper
authors.initials: J
authors.lastname: Hallas
authors.forename: Jens
authors.initials: J
authors.lastname: Søndergaard
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D003157:Community Pharmacy Services / Q000458:organization & administration*; D003718:Denmark; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D010595:Pharmacists / Q000458:organization & administration*; D055553:Prescription Drugs / Q000008:administration & dosage / Q000009:adverse effects*; D024382:Professional Role; D011446:Prospective Studies; D019037:Urban Health Services; D055815:Young Adult
chemical_list: D055553:Prescription Drugs
references.citation: Res Social Adm Pharm. 2006 Dec;2(4):458-78
references.pmid: 17161806
references.citation: Br J Clin Pharmacol. 2001 Jul;52(1):85-91
references.pmid: 11453894
references.citation: Res Social Adm Pharm. 2010 Sep;6(3):174-84
references.pmid: 20813331
references.citation: Ann Pharmacother. 2007 Nov;41(11):1825-32
references.pmid: 17925500
references.citation: Tidsskr Nor Laegeforen. 2009 Sep 24;129(18):1846-9
references.pmid: 19844274
references.citation: Ann Pharmacother. 1992 Dec;26(12):1580-4
references.pmid: 1482816
references.citation: Tidsskr Nor Laegeforen. 2006 Jan 26;126(3):296-8
references.pmid: 16440032
references.citation: J Am Med Inform Assoc. 2010 Jan-Feb;17(1):78-84
references.pmid: 20064806
references.citation: Br J Clin Pharmacol. 2004 Nov;58(5):503-11
references.pmid: 15521898
references.citation: J Am Pharm Assoc (2003). 2003 Sep-Oct;43(5):612-21
references.pmid: 14626754
references.citation: Br J Clin Pharmacol. 2009 Jun;67(6):629-40
references.pmid: 19094162
references.citation: Am J Health Syst Pharm. 1998 Jun 1;55(11):1141-5
references.pmid: 9626376
references.citation: J Clin Pharm Ther. 2007 Apr;32(2):133-42
references.pmid: 17381663
references.citation: Pharmacoepidemiol Drug Saf. 2009 Nov;18(11):992-9
references.pmid: 19634116
references.citation: Pharm World Sci. 2001 Jun;23(3):98-101
references.pmid: 11468883
references.citation: J Am Pharm Assoc (Wash). 2003 Mar-Apr;43(2):191-200
references.pmid: 12688437
references.citation: Pharm World Sci. 2003 Apr;25(2):65-9
references.pmid: 12774566
references.citation: BMC Med Inform Decis Mak. 2009 Jan 26;9:8
references.pmid: 19171038
references.citation: Drug Saf. 2005;28(10):891-900
references.pmid: 16180938
references.citation: Am J Hosp Pharm. 1990 Mar;47(3):533-43
references.pmid: 2316538
references.citation: Qual Saf Health Care. 2007 Aug;16(4):291-6
references.pmid: 17693678
references.citation: Indian J Community Med. 2010 Jan;35(1):70-3
references.pmid: 20606924
references.citation: J Am Pharm Assoc (2003). 2009 Jan-Feb;49(1):59-64
references.pmid: 19196598
references.citation: Dan Med Bull. 1997 Sep;44(4):445-8
references.pmid: 9377907
references.citation: Br J Clin Pharmacol. 1999 Jun;47(6):695-700
references.pmid: 10383549
references.citation: Pharm World Sci. 2006 Feb;28(1):33-8
references.pmid: 16703267