title: [Drug sensitivity of causative agents in ocular infection of external adnexa and anterior segments--multicenter study of causative agents and drug sensitivity of ocular infection by the Japanese Association for Ocular Infection part II].
abstract: OBJECTIVE
  To report the drug sensitivity of causative agents produced by ocular infection of external adnexa and anterior segments investigated by the nationwide survey conducted by Japanese Association for Ocular Infection between September, 2007 and August, 2008.
  
  
  METHODS
  Among all strains isolated, causative and presumed causative agents were selected according to the criteria described, and drug sensitivity tests were conducted by minimum inhibitory concentrations (MIC) with 10 kinds of antimicrobial agents including 5 fluoroquinolones.
  
  
  RESULTS
  Among 281 causative isolates, cefmenoxime (CMX) showed the highest sensitivity, followed by fluoroquinolones. Staphylococci and Streptococci were more sensitive to fluoroquinolones when compared to the others. Haemophilus influenzae was very sensitive to all fluoroquinolones. Corynebacterium spp. and Propionibacterium acnes were most sensitive to CMX and erythromycin respectively.
  
  
  CONCLUSIONS
  CMX and fluoroquinolones showed generally good sensitivity among causative pathogens of ocular infection.
authors.affiliation: Hatano Eye Clinic, Japan. hrsh@ha-ta-no.jp
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Hatano
authors.forename: Yoshitsugu
authors.initials: Y
authors.lastname: Inoue
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Ohashi
authors.forename: Yoshikazu
authors.initials: Y
authors.lastname: Shimomura
authors.forename: Masako
authors.initials: M
authors.lastname: Sakamoto
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Okamoto
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000890:Anti-Infective Agents / Q000494:pharmacology*; D015281:Cefmenoxime / Q000494:pharmacology; D002648:Child; D002675:Child, Preschool; D015818:Eye Infections, Bacterial / Q000382:microbiology*; D005260:Female; D024841:Fluoroquinolones / Q000494:pharmacology; D006193:Haemophilus influenzae / Q000187:drug effects; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged
chemical_list: D000890:Anti-Infective Agents; D024841:Fluoroquinolones; D015281:Cefmenoxime