title: Growth and development of the root apical meristem.
abstract: A key question in plant developmental biology is how cell division and cell differentiation are balanced to modulate organ growth and shape organ size. In recent years, several advances have been made in understanding how this balance is achieved during root development. In the Arabidopsis root meristem, stem cells in the apical region of the meristem self-renew and produce daughter cells that differentiate in the distal meristem transition zone. Several factors have been implicated in controlling the different functional zones of the root meristem to modulate root growth; among these, plant hormones have been shown to play a main role. In this review, we summarize recent findings regarding the role of hormone signaling and transcriptional networks in regulating root development.
authors.affiliation: Dipartimento di Biologia e Biotecnologie Charles Darwin, Laboratory of Functional Genomics and Proteomics of Model Systems, Università Sapienza - via dei Sardi, 70-00185 Rome, Italy.
authors.forename: Serena
authors.initials: S
authors.lastname: Perilli
authors.forename: Riccardo
authors.initials: R
authors.lastname: Di Mambro
authors.forename: Sabrina
authors.initials: S
authors.lastname: Sabatini
mesh_terms: D017360:Arabidopsis / Q000166:cytology / Q000196:embryology; D018519:Meristem / Q000196:embryology / Q000254:growth & development*; D008954:Models, Biological; D055153:Stem Cell Niche