title: Strategy for management of retroperitoneal tumors with caval tumor thrombus.
abstract: The surgical management of retroperitoneal tumors extending into the inferior vena cava (IVC) can be challenging. Although Wilms' tumor is the most common retroperitoneal tumor extending into the IVC, one must approach these tumors systematically as other diagnoses are possible. We present 4 consecutive cases of retroperitoneal tumors with IVC extension as a basis for a management strategy in approaching these patients. Despite similar presentations, these cases illustrate the nuances in surgical management and need for multidisciplinary care with the pediatric oncologists, pediatric surgeons, and pediatric cardiac surgeons.
authors.affiliation: Department of Pediatric Surgery, Children's National Medical Center, Washington, DC 20010, USA.
authors.forename: Nini
authors.initials: N
authors.lastname: Khozeimeh
authors.forename: Pranava
authors.initials: P
authors.lastname: Sinha
authors.forename: Jeffrey S
authors.initials: JS
authors.lastname: Dome
authors.forename: Philip C
authors.initials: PC
authors.lastname: Guzzetta
mesh_terms: D000310:Adrenal Gland Neoplasms / Q000473:pathology / Q000601:surgery; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D003131:Combined Modality Therapy; D003609:Dactinomycin / Q000008:administration & dosage; D019468:Disease Management; D004317:Doxorubicin / Q000008:administration & dosage; D005260:Female; D006325:Heart Atria / Q000473:pathology; D006801:Humans; D007680:Kidney Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000601:surgery; D008175:Lung Neoplasms / Q000556:secondary; D008297:Male; D008511:Medicine; D009361:Neoplasm Invasiveness; D009360:Neoplastic Cells, Circulating / Q000473:pathology; D009392:Nephrectomy; D009447:Neuroblastoma / Q000473:pathology / Q000601:surgery; D010348:Patient Care Team; D012186:Retroperitoneal Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000601:surgery*; D018227:Sarcoma, Clear Cell / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery; D014057:Tomography, X-Ray Computed; D014682:Vena Cava, Inferior / Q000473:pathology*; D014750:Vincristine / Q000008:administration & dosage; D009396:Wilms Tumor / Q000188:drug therapy / Q000473:pathology / Q000556:secondary / Q000601:surgery
chemical_list: D003609:Dactinomycin; D014750:Vincristine; D004317:Doxorubicin