title: Quantitation of human herpesvirus-6 (HHV-6) DNA in a cord blood transplant recipient with chromosomal integration of HHV-6.
abstract: Chromosomal integration of the human herpesvirus-6 (HHV-6) genome (CIHHV-6) is an important consideration if HHV-6 DNA is detected during the course of transplantation. A 4-year-old girl with refractory anemia with excess blasts type-2 was diagnosed with CIHHV-6 before a cord blood transplantation. HHV-6 DNA was serially quantitated by polymerase chain reaction assay in the transplant period. The possibility of HHV-6 reactivation in a transplant recipient with CIHHV-6 was suspected in our case.
authors.affiliation: Department of Pediatrics, Children's Hospital of Michigan, Wayne State University School of Medicine, Detroit, Michigan 48201-2119, USA. dkobayas@dmc.org
authors.forename: D
authors.initials: D
authors.lastname: Kobayashi
authors.forename: K
authors.initials: K
authors.lastname: Kogawa
authors.forename: K
authors.initials: K
authors.lastname: Imai
authors.forename: T
authors.initials: T
authors.lastname: Tanaka
authors.forename: S
authors.initials: S
authors.lastname: Hiroi
authors.forename: H
authors.initials: H
authors.lastname: Satoh
authors.forename: K
authors.initials: K
authors.lastname: Tanaka-Taya
authors.forename: S
authors.initials: S
authors.lastname: Nonoyama
mesh_terms: D000754:Anemia, Refractory, with Excess of Blasts / Q000150:complications / Q000628:therapy; D002675:Child, Preschool; D036101:Cord Blood Stem Cell Transplantation; D004279:DNA, Viral / Q000032:analysis; D005260:Female; D015654:Herpesvirus 6, Human / Q000235:genetics*; D006801:Humans; D016133:Polymerase Chain Reaction; D011183:Postoperative Complications; D019349:Roseolovirus Infections / Q000235:genetics*; D019562:Viral Load; D016662:Virus Integration / Q000235:genetics*
chemical_list: D004279:DNA, Viral