title: Oleic acid produced by a marine Vibrio spp. acts as an anti-Vibrio parahaemolyticus agent.
abstract: It is known that some strains of Vibrio parahaemolyticus are responsible for gastroenteric diseases caused by the ingestion of marine organisms contaminated with these bacterial strains. Organic products that show inhibitory activity on the growth of the pathogenic V. parahaemolyticus were extracted from a Vibrio native in the north of Chile. The inhibitory organic products were isolated by reverse phase chromatography and permeation by Sephadex LH20, and were characterized by spectroscopic and spectrometric techniques. The results showed that the prevailing active product is oleic acid, which was compared with standards by gas chromatography and high-performance liquid chromatography (HPLC). These active products might be useful for controlling the proliferation of pathogenic clones of V. parahaemolyticus.
authors.affiliation: Microbial Ecology Laboratory, Faculty of Marine Resources, Antofagasta University, Antofagasta 1310000, Chile.|Doctorate Applied Science, Mention Coastal Marine Systems, Faculty of Marine Resources, Antofagasta University, Antofagasta 1310000, Chile.
authors.forename: Yanett
authors.initials: Y
authors.lastname: Leyton
authors.affiliation: Laboratory of Natural Products, Department of Chemistry, Antofagasta University, Antofagasta 1310000, Chile.
authors.forename: Jorge
authors.initials: J
authors.lastname: Borquez
authors.affiliation: Institute of Natural Products and Agrobiology, CSIC, La Laguna, Tenerife 38206, Spain.
authors.forename: José
authors.initials: J
authors.lastname: Darias
authors.affiliation: Institute of Natural Products and Agrobiology, CSIC, La Laguna, Tenerife 38206, Spain.
authors.forename: Mercedes
authors.initials: M
authors.lastname: Cueto
authors.affiliation: Institute of Natural Products and Agrobiology, CSIC, La Laguna, Tenerife 38206, Spain.
authors.forename: Ana R
authors.initials: AR
authors.lastname: Díaz-Marrero
authors.affiliation: Microbial Ecology Laboratory, Faculty of Marine Resources, Antofagasta University, Antofagasta 1310000, Chile.
authors.forename: Carlos
authors.initials: C
authors.lastname: Riquelme
mesh_terms: D000890:Anti-Infective Agents / Q000302:isolation & purification / Q000494:pharmacology*; D002849:Chromatography, Gas; D002851:Chromatography, High Pressure Liquid; D056148:Chromatography, Reverse-Phase; D008826:Microbial Sensitivity Tests; D019301:Oleic Acid / Q000302:isolation & purification / Q000494:pharmacology* / Q000502:physiology; D014733:Vibrio / Q000737:chemistry / Q000502:physiology*; D014736:Vibrio parahaemolyticus / Q000187:drug effects*
chemical_list: D000890:Anti-Infective Agents; D019301:Oleic Acid
references.citation: Int J Food Microbiol. 2007 Jul 15;117(3):270-5
references.pmid: 17521760
references.citation: FEMS Immunol Med Microbiol. 2003 May 15;36(1-2):9-17
references.pmid: 12727360
references.citation: Mar Drugs. 2009 Jul 21;7(3):341-54
references.pmid: 19841718
references.citation: J Basic Microbiol. 2007 Feb;47(1):84-6
references.pmid: 17304623
references.citation: Immunobiology. 2011 Mar;216(3):409-15
references.pmid: 20655616
references.citation: Int J Food Microbiol. 2010 Jul 15;141(3):242-7
references.pmid: 20573415
references.citation: Arch Oral Biol. 2010 Aug;55(8):555-60
references.pmid: 20541177
references.citation: J Med Microbiol. 1992 Jan;36(1):56-60
references.pmid: 1731060
references.citation: J Nat Prod. 1999 Sep;62(9):1333-5
references.pmid: 10514329
references.citation: J Nutr Biochem. 2004 Sep;15(9):540-7
references.pmid: 15350986
references.citation: Nat Prod Rep. 2006 Feb;23(1):26-78
references.pmid: 16453031
references.citation: Am J Clin Nutr. 2000 Jan;71(1 Suppl):361S-6S
references.pmid: 10617998
references.citation: Emerg Infect Dis. 2009 Feb;15(2):163-8
references.pmid: 19193258
references.citation: Antimicrob Agents Chemother. 2009 Aug;53(8):3375-83
references.pmid: 19470513
references.citation: J Invertebr Pathol. 2007 Oct;96(2):147-50
references.pmid: 17544437
references.citation: Bacteriol Rev. 1954 Jun;18(2):147-63
references.pmid: 13159785
references.citation: J Nat Prod. 2004 Aug;67(8):1216-38
references.pmid: 15332835
references.citation: FEBS Lett. 2005 Sep 26;579(23):5157-62
references.pmid: 16146629
references.citation: J Appl Bacteriol. 1988 Aug;65(2):97-101
references.pmid: 3204073
references.citation: Nucleic Acids Res. 1994 Nov 11;22(22):4673-80
references.pmid: 7984417
references.citation: J Mol Biol. 1981 May 15;148(2):107-27
references.pmid: 7028991
references.citation: Microb Ecol. 2010 Oct;60(3):599-605
references.pmid: 20454959
references.citation: Int J Antimicrob Agents. 2004 Jun;23(6):613-9
references.pmid: 15194133