title: Assessment of QSARS for Predicting Fate and Effects of Chemicals in the Environment: An International European Project.
abstract: Abstract   In 1993, an international project on QSAR has been started with funding from the Commission of the European Union. The first part of the project is focused on preparing an overview of existing models for the prediction of environmental parameters such as bioconcentration, sorption, degradation and ecotoxicity. Emphasis will be given to defining the limitations of the models. Since all models, including QSARs, have their limitations, it is important that these limitations are known in case QSARs are actually used and applied within the risk assessment context. The second part of the project is directed towards experimental research on new developments with emphasis on the use of multivariate techniques and quantum chemical properties. In this short paper, a general outline of the project will be given, as well as some first results. Results of experimental work within this project will be published in the proceedings of the 6th International Workshop on QSAR in Environmental Sciences and will appear in this same journal.
authors.affiliation: a    Research Institute of Toxicology, Utrecht University   ,  P.O. Box 80176 ,  3508 TD ,  Utrecht ,    The Netherlands.
authors.forename: J
authors.initials: J
authors.lastname: Hermens
authors.forename: S
authors.initials: S
authors.lastname: Balaz
authors.forename: J
authors.initials: J
authors.lastname: Damborsky
authors.forename: W
authors.initials: W
authors.lastname: Karcher
authors.forename: M
authors.initials: M
authors.lastname: Müller
authors.forename: W
authors.initials: W
authors.lastname: Peijnenburg
authors.forename: A
authors.initials: A
authors.lastname: Sabljic
authors.forename: M
authors.initials: M
authors.lastname: Sjöström