title: Natural history of venous thromboembolism.
abstract: Venous thromboembolism (VTE) originates in systemic venous thrombosis and has different etiological mechanisms and natural history from arterial thrombosis. VTE typically originates as deep venous thrombosis in a lower extremity, where it may give rise to acute symptoms “upstream” from the obstructed vein, result in pulmonary embolism, and/or cause chronic venous obstruction. Pulmonary embolism may result in acute respiratory symptoms, cardiovascular collapse and, uncommonly, may also cause chronic disease.
authors.affiliation: Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of California, San Diego School of Medicine, 200 West Arbor Drive, San Diego, CA 92103-8378, USA. t1morris@ucsd.edu
authors.forename: Timothy A
authors.initials: TA
authors.lastname: Morris
mesh_terms: D002908:Chronic Disease; D006439:Hemodynamics; D006801:Humans; D006976:Hypertension, Pulmonary / Q000209:etiology; D010960:Plasminogen Activators / Q000627:therapeutic use; D011655:Pulmonary Embolism / Q000150:complications / Q000188:drug therapy / Q000209:etiology*; D012119:Respiration; D020246:Venous Thrombosis / Q000150:complications / Q000209:etiology*; D014692:Ventilation-Perfusion Ratio
chemical_list: D010960:Plasminogen Activators