title: Daphnia magna, a host for evaluation of bacterial virulence.
abstract: We show that Daphnia magna can be used to assess acute virulence of pathogens relevant to human health, such as Pseudomonas aeruginosa or Photorhabdus asymbiotica. Analysis of bacterial mutants suggests that P. aeruginosa uses similar mechanisms to infect Daphnia and other hosts.
authors.affiliation: Université de Genève, Centre Médical Universitaire, Département de Physiologie Cellulaire et Métabolisme, Genèva, Switzerland.
authors.forename: Marion
authors.initials: M
authors.lastname: Le Coadic
authors.forename: Marianne
authors.initials: M
authors.lastname: Simon
authors.forename: Anna
authors.initials: A
authors.lastname: Marchetti
authors.forename: Dieter
authors.initials: D
authors.lastname: Ebert
authors.forename: Pierre
authors.initials: P
authors.lastname: Cosson
mesh_terms: D000818:Animals; D003621:Daphnia / Q000382:microbiology*; D006801:Humans; D020637:Photorhabdus / Q000235:genetics / Q000472:pathogenicity*; D011550:Pseudomonas aeruginosa / Q000235:genetics / Q000472:pathogenicity*; D016019:Survival Analysis; D014774:Virulence
references.citation: Cell Microbiol. 2006 Jan;8(1):139-48
references.pmid: 16367873
references.citation: Nat Protoc. 2009;4(1):25-30
references.pmid: 19131953
references.citation: Environ Microbiol. 2007 Mar;9(3):563-75
references.pmid: 17298357
references.citation: FEMS Microbiol Lett. 2009 Oct;299(1):110-9
references.pmid: 19686345
references.citation: Curr Opin Microbiol. 2003 Feb;6(1):56-60
references.pmid: 12615220
references.citation: Curr Opin Microbiol. 2008 Jun;11(3):290-301
references.pmid: 18556238
references.citation: Curr Opin Microbiol. 2007 Feb;10(1):10-6
references.pmid: 17178462
references.citation: Cell Microbiol. 2008 Mar;10(3):729-40
references.pmid: 18042255
references.citation: J Bacteriol. 2002 Jun;184(11):3027-33
references.pmid: 12003944
references.citation: Microbes Infect. 2010 Mar;12(3):182-9
references.pmid: 20034588
references.citation: Drugs. 2007;67(3):351-68
references.pmid: 17335295