title: [The impact of systematic lymphadenectomy for early-stage ovarian carcinomas].
abstract: Among the 161 cases of pT1 ovarian cancer treated at our hospital during the last 25 years, the impact of systematic lymphadenectomy was evaluated in 93 cases of the pT1N0M0 group(N0 group), 59 cases of the pT1NxM0(Nx group), and 9 cases of the pT1N1M0(N1 group). Significantly greater relapse-free survival(RFS)and overall survival(OS)were observed in 108 cases of the N0+N1 group compared to the Nx group(p=0. 006, p=0. 02). Multivariate analysis showed that systematic lymphadenectomy was a significant prognostic factor(hazard ratio 0. 473(95%CI, 0. 235-0. 951; p=0. 036). The present study suggested the systematic lymphadenectomy had a significant therapeutic effect on pT1 stage ovarian cancers.
authors.affiliation: Dept. of Obstetrics and Gynecology, National Defense Medical College Hospital, Japan.
authors.forename: Morikazu
authors.initials: M
authors.lastname: Miyamoto
authors.forename: Masashi
authors.initials: M
authors.lastname: Takano
authors.forename: Tomoko
authors.initials: T
authors.lastname: Goto
authors.forename: Takashi
authors.initials: T
authors.lastname: Shibutani
authors.forename: Hiroko
authors.initials: H
authors.lastname: Matsuura
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Soyama
authors.forename: Taishi
authors.initials: T
authors.lastname: Akimoto
authors.forename: Kazuhiko
authors.initials: K
authors.lastname: Asai
authors.forename: Akihiro
authors.initials: A
authors.lastname: Kawashima
authors.forename: Akio
authors.initials: A
authors.lastname: Watanabe
authors.forename: Masafumi
authors.initials: M
authors.lastname: Kato
authors.forename: Tomoyuki
authors.initials: T
authors.lastname: Yoshikawa
authors.forename: Naoki
authors.initials: N
authors.lastname: Sasaki
authors.forename: Junko
authors.initials: J
authors.lastname: Hirata
authors.forename: Hidenori
authors.initials: H
authors.lastname: Sasa
authors.forename: Kenichi
authors.initials: K
authors.lastname: Furuya
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000077216:Carcinoma, Ovarian Epithelial; D005260:Female; D006801:Humans; D008197:Lymph Node Excision; D008875:Middle Aged; D009367:Neoplasm Staging; D009375:Neoplasms, Glandular and Epithelial / Q000473:pathology / Q000601:surgery*; D010051:Ovarian Neoplasms / Q000473:pathology / Q000601:surgery*; D012189:Retrospective Studies; D015996:Survival Rate; D055815:Young Adult