title: Toxins and adverse drug reactions affecting the equine nervous system.
abstract: This article provides an overview of the more common toxins and adverse drug reactions, along with more rare toxins and reactions (Table 1), that result in neurologic dysfunction in horses. A wide variety of symptoms, treatments, and outcomes are seen with toxic neurologic disease in horses. An in-depth history and thorough physical examination are needed to determine if a toxin or adverse drug reaction is responsible for the clinical signs. Once a toxin or adverse drug reaction is identified, the specific antidote, if available, and supportive care should be administered promptly.
authors.affiliation: William Pritchard Veterinary Medical Teaching Hospital, University of California, Davis, One Garrod Avenue, Davis, CA 95616, USA. drdawson@ucdavis.edu
authors.forename: Dominic R
authors.initials: DR
authors.lastname: Dawson
mesh_terms: D000818:Animals; D006734:Horse Diseases / Q000139:chemically induced*; D006736:Horses; D009422:Nervous System Diseases / Q000139:chemically induced / Q000662:veterinary*; D014118:Toxins, Biological / Q000506:poisoning*; D019155:Veterinary Drugs / Q000009:adverse effects*
chemical_list: D014118:Toxins, Biological; D019155:Veterinary Drugs