title: Coupling electrodeposition with layer-by-layer assembly to address proteins within microfluidic channels.
abstract: Two thin-film assembly methods are coupled to address proteins. Electrodeposition confers programmability and generates a template for layer-by-layer (LbL) assembly. LbL enables precise control of film thickness and the incorporation of labile biological components. The capabilities are demonstrated using glucose oxidase (GOx) based electrochemical biosensing within a microfabricated fluidic device.
authors.affiliation: School of Materials Science and Engineering, Wuhan University of Technology, PR China.
authors.forename: Yifeng
authors.initials: Y
authors.lastname: Wang
authors.forename: Yi
authors.initials: Y
authors.lastname: Liu
authors.forename: Yi
authors.initials: Y
authors.lastname: Cheng
authors.forename: Eunkyoung
authors.initials: E
authors.lastname: Kim
authors.forename: Gary W
authors.initials: GW
authors.lastname: Rubloff
authors.forename: William E
authors.initials: WE
authors.lastname: Bentley
authors.forename: Gregory F
authors.initials: GF
authors.lastname: Payne
mesh_terms: D000464:Alginates / Q000737:chemistry; D000465:Algorithms; D000818:Animals; D001234:Aspergillus niger / Q000378:metabolism; D003386:Brachyura; D048271:Chitosan / Q000737:chemistry; D004563:Electrochemistry / Q000379:methods; D004595:Electroplating / Q000379:methods*; D004867:Equipment Design; D005949:Glucose Oxidase / Q000737:chemistry; D020723:Glucuronic Acid / Q000737:chemistry; D006603:Hexuronic Acids / Q000737:chemistry; D008051:Lipid Bilayers / Q000737:chemistry; D044662:Macrocystis / Q000378:metabolism; D008422:Materials Testing; D044085:Microfluidics / Q000379:methods*; D008853:Microscopy / Q000379:methods; D008856:Microscopy, Fluorescence / Q000379:methods; D011108:Polymers / Q000737:chemistry; D013059:Spectrum Analysis, Raman / Q000379:methods; D013499:Surface Properties
chemical_list: D000464:Alginates; D006603:Hexuronic Acids; D008051:Lipid Bilayers; D011108:Polymers; D020723:Glucuronic Acid; D048271:Chitosan; D005949:Glucose Oxidase