title: Extended resections for colorectal cancer - indications for supraradical lymphadenectomy.
abstract: The laparoscopic approach to standard resections in colorectal cancer has proven that it may provide equal rates of R0 resections and adequate retrieval of lymph nodes as open procedures if performed by experienced hands. There might be difficulties in more advanced tumors or those with lymphatic spread beyond typical drainage areas and more extensive operations might be required. An atypical pattern of lymphatic spread often is associated with other adverse factors such as multifocality of primary cancers and adverse tumorbiological factors such as grade. Such patient subgroups may be defined beforehand and include particularly patients with underlying ulcerative colitis. Repetitively, extended lymph node dissection approaches have been advocated, however neither in randomised trails nor in meta-analysis has a more favourable outcome of patients undergoing such extended lymphatic dissections been demonstrated. Sticking to the rules of classical dissection of lymphatic drainage basins with removal of adequate lymph node numbers is one corner stone for successful treatment of colorectal cancer. The other one refers to a detailed description of the procedure performed in order to make the surgical procedure trackable.
authors.affiliation: Division of Surgical Oncology and Thoracic Surgery, Mannheim University Medical Center, University of Heidelberg, Heidelberg, Germany. peter.hohenberger@umm.de
authors.forename: P
authors.initials: P
authors.lastname: Hohenberger
authors.forename: W
authors.initials: W
authors.lastname: Du
authors.forename: S
authors.initials: S
authors.lastname: Post
mesh_terms: D003110:Colonic Neoplasms / Q000473:pathology* / Q000601:surgery; D019983:Guideline Adherence; D006801:Humans; D010535:Laparoscopy; D008197:Lymph Node Excision / Q000592:standards*; D008207:Lymphatic Metastasis; D009367:Neoplasm Staging; D017410:Practice Guidelines as Topic; D019984:Quality Indicators, Health Care; D012004:Rectal Neoplasms / Q000473:pathology* / Q000601:surgery