title: Natural presence of NS3 protease R155K hepatitis C virus variants with decreased sensitivity to protease inhibitors.
authors.forename: Philippe
authors.initials: P
authors.lastname: Colson
authors.forename: Raj
authors.initials: R
authors.lastname: Purgus
authors.forename: Patrick
authors.initials: P
authors.lastname: Borentain
authors.forename: René
authors.initials: R
authors.lastname: Gérolami
mesh_terms: D024882:Drug Resistance, Viral / Q000235:genetics*; D014644:Genetic Variation; D016174:Hepacivirus / Q000187:drug effects / Q000235:genetics*; D006526:Hepatitis C / Q000188:drug therapy / Q000821:virology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009154:Mutation; D011480:Protease Inhibitors / Q000494:pharmacology*; D017361:Viral Nonstructural Proteins / Q000737:chemistry / Q000235:genetics*; D012697:Serine Endopeptidases; D043583:Nucleoside-Triphosphatase; D053487:DEAD-box RNA Helicases; D000085242:Viral Proteases
chemical_list: D011480:Protease Inhibitors; D017361:Viral Nonstructural Proteins; C084422:NS3 protein, hepatitis C virus; D012697:Serine Endopeptidases; D043583:Nucleoside-Triphosphatase; D053487:DEAD-box RNA Helicases; D000085242:Viral Proteases