title: The discovery of lapatinib (GW572016).
authors.affiliation: BioAgilytix Labs, Inc., Durham, NC, USA.
authors.forename: David
authors.initials: D
authors.lastname: Rusnak
authors.forename: Tona M
authors.initials: TM
authors.lastname: Gilmer
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000494:pharmacology*; D002455:Cell Division / Q000187:drug effects*; D004791:Enzyme Inhibitors / Q000494:pharmacology*; D066246:ErbB Receptors / Q000037:antagonists & inhibitors*; D005260:Female; D005663:Furans / Q000494:pharmacology*; D006801:Humans; D009374:Neoplasms, Experimental / Q000188:drug therapy*; D011799:Quinazolines / Q000494:pharmacology*; D018719:Erb-b2 Receptor Tyrosine Kinases / Q000037:antagonists & inhibitors*
chemical_list: D000970:Antineoplastic Agents; D004791:Enzyme Inhibitors; D066246:ErbB Receptors; D005663:Furans; D011799:Quinazolines; D018719:Erb-b2 Receptor Tyrosine Kinases