title: Multidimensional predictors of fatigue among octogenarians and centenarians.
abstract: BACKGROUND
  Fatigue is a common and frequently observed complaint among older adults. However, knowledge about the nature and correlates of fatigue in old age is very limited.
  
  
  OBJECTIVE
  This study examined the relationship of functional indicators, psychological and situational factors and fatigue for 210 octogenarians and centenarians from the Georgia Centenarian Study.
  
  
  METHODS
  Three indicators of functional capacity (self-rated health, instrumental activities of daily living, physical activities of daily living), two indicators of psychological well-being (positive and negative affect), two indicators of situational factors (social network and social support), and a multidimensional fatigue scale were used. Blocked multiple regression analyses were computed to examine significant factors related to fatigue. In addition, multi-group analysis in structural equation modeling was used to investigate residential differences (i.e., long-term care facilities vs. private homes) in the relationship between significant factors and fatigue.
  
  
  RESULTS
  Blocked multiple regression analyses indicated that two indicators of functional capacity, self-rated health and instrumental activities of daily living, both positive and negative affect, and social support were significant predictors of fatigue among oldest-old adults. The multiple group analysis in structural equation modeling revealed a significant difference among oldest-old adults based on residential status.
  
  
  CONCLUSIONS
  The results suggest that we should not consider fatigue as merely an unpleasant physical symptom, but rather adopt a perspective that different factors such as psychosocial aspects can influence fatigue in advanced later life.
authors.affiliation: Scott & White Health Care, Texas A&M Health Science Center, School of Rural Public Health, College Station, TX 77843-1266, USA. jinmyoung.cho@srph.tamhsc.edu
authors.forename: Jinmyoung
authors.initials: J
authors.lastname: Cho
authors.forename: Peter
authors.initials: P
authors.lastname: Martin
authors.forename: Jennifer
authors.initials: J
authors.lastname: Margrett
authors.forename: Maurice
authors.initials: M
authors.lastname: MacDonald
authors.forename: Mary Ann
authors.initials: MA
authors.lastname: Johnson
authors.forename: Leonard W
authors.initials: LW
authors.lastname: Poon
authors.forename: S M
authors.initials: SM
authors.lastname: Jazwinski
authors.forename: R C
authors.initials: RC
authors.lastname: Green
authors.forename: M
authors.initials: M
authors.lastname: Gearing
authors.forename: J L
authors.initials: JL
authors.lastname: Woodard
authors.forename: J S
authors.initials: JS
authors.lastname: Tenover
authors.forename: I C
authors.initials: IC
authors.lastname: Siegler
authors.forename: C
authors.initials: C
authors.lastname: Rott
authors.forename: W L
authors.initials: WL
authors.lastname: Rodgers
authors.forename: D
authors.initials: D
authors.lastname: Hausman
authors.forename: J
authors.initials: J
authors.lastname: Arnold
authors.forename: A
authors.initials: A
authors.lastname: Davey
mesh_terms: D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000502:physiology*; D015331:Cohort Studies; D005221:Fatigue / Q000175:diagnosis* / Q000453:epidemiology*; D005260:Female; D005500:Follow-Up Studies; D005845:Georgia; D015577:Geriatric Assessment / Q000379:methods; D006305:Health Status Indicators; D006801:Humans; D057187:Independent Living; D008136:Longevity / Q000502:physiology; D008297:Male; D015999:Multivariate Analysis; D011237:Predictive Value of Tests; D015995:Prevalence; D011446:Prospective Studies; D012044:Regression Analysis; D012720:Severity of Illness Index; D017678:Sex Distribution; D018434:Sickness Impact Profile; D012866:Skilled Nursing Facilities
references.citation: Chest. 2004 Feb;125(2):439-45
references.pmid: 14769722
references.citation: J Aging Res. 2011;2011:605041
references.pmid: 21748008
references.citation: Pain. 2007 Mar;128(1-2):128-35
references.pmid: 17055648
references.citation: J Rheumatol. 2006 Aug;33(8):1496-502
references.pmid: 16783859
references.citation: Age Ageing. 2010 Sep;39(5):617-23
references.pmid: 20639514
references.citation: Aust Fam Physician. 2003 Aug;32(8):663-6
references.pmid: 12973880
references.citation: Phys Med Rehabil Clin N Am. 2005 Feb;16(1):91-108
references.pmid: 15561546
references.citation: Med Care. 1999 Oct;37(10):1078-83
references.pmid: 10524374
references.citation: J Psychiatr Res. 1975 Nov;12(3):189-98
references.pmid: 1202204
references.citation: J Appl Physiol (1985). 2002 Nov;93(5):1813-23
references.pmid: 12381770
references.citation: Res Nurs Health. 1992 Jun;15(3):199-207
references.pmid: 1354883
references.citation: Semin Oncol Nurs. 1995 Feb;11(1):17-22
references.pmid: 7740218
references.citation: Oncol Nurs Forum. 1991 Jul;18(5):883-7
references.pmid: 1891417
references.citation: J Clin Nurs. 2010 Jun;19(11-12):1588-96
references.pmid: 20579199
references.citation: Cancer. 2004 Oct 1;101(7):1655-63
references.pmid: 15378496
references.citation: Oncol Nurs Forum. 2004 Nov 16;31(6):1069-75
references.pmid: 15547630
references.citation: J Gerontol B Psychol Sci Soc Sci. 2000 Mar;55(2):P107-16
references.pmid: 10794189
references.citation: Annu Rev Gerontol Geriatr. 2007 Jan 1;27(1):231-264
references.pmid: 21852888
references.citation: J Clin Epidemiol. 2002 Oct;55(10):965-73
references.pmid: 12464372
references.citation: Semin Oncol Nurs. 1987 Nov;3(4):242-7
references.pmid: 3321273
references.citation: Ann Intern Med. 2001 Sep 4;135(5):313-21
references.pmid: 11529694
references.citation: West J Nurs Res. 2002 Jun;24(4):441-53
references.pmid: 12035915
references.citation: J Appl Physiol (1985). 2003 Oct;95(4):1728-36
references.pmid: 12970378
references.citation: Qual Life Res. 1992 Dec;1(6):375-84
references.pmid: 1299470
references.citation: J Appl Physiol (1985). 2001 Dec;91(6):2686-94
references.pmid: 11717235
references.citation: Psychosom Med. 2003 Sep-Oct;65(5):771-7
references.pmid: 14508019
references.citation: Gerontologist. 2001 Dec;41(6):768-77
references.pmid: 11723345
references.citation: J Am Geriatr Soc. 2004 Nov;52(11):1963-5
references.pmid: 15507083
references.citation: Arch Intern Med. 2007 Dec 10;167(22):2503-8
references.pmid: 18071174
references.citation: Behav Med. 2001 Winter;26(4):159-68
references.pmid: 11409218
references.citation: Cancer Nurs. 1988 Jun;11(3):186-94
references.pmid: 3401854
references.citation: West J Nurs Res. 2003 Jun;25(4):419-33
references.pmid: 12790057
references.citation: ANS Adv Nurs Sci. 1997 Mar;19(3):14-27
references.pmid: 9055027
references.citation: J Psychosom Res. 1995 Apr;39(3):315-25
references.pmid: 7636775
references.citation: J Am Geriatr Soc. 2010 May;58(5):967-75
references.pmid: 20722821
references.citation: J Gerontol B Psychol Sci Soc Sci. 2002 Mar;57(2):P144-52
references.pmid: 11867662
references.citation: J Womens Health. 1998 Feb;7(1):69-76
references.pmid: 9511134
references.citation: J Pain Symptom Manage. 2005 Feb;29(2):130-55
references.pmid: 15733806
references.citation: Oncol Nurs Forum. 1991 Jan-Feb;18(1):81-7
references.pmid: 2003120
references.citation: Vital Health Stat 13. 2009 Jun;(167):1-155
references.pmid: 19655659
references.citation: Eur J Appl Physiol Occup Physiol. 1993;66(3):254-62
references.pmid: 8477683
references.citation: J Appl Physiol (1985). 2004 Nov;97(5):1723-32
references.pmid: 15208285
references.citation: Int J Aging Hum Dev. 2011;72(2):137-54
references.pmid: 21639014
references.citation: Aust Fam Physician. 2003 Nov;32(11):873-6
references.pmid: 14650780