title: A late-stage intermediate in salinomycin biosynthesis is revealed by specific mutation in the biosynthetic gene cluster.
authors.affiliation: Department of Biochemistry, University of Cambridge, Cambridge, UK.
authors.forename: Marie E
authors.initials: ME
authors.lastname: Yurkovich
authors.forename: Petros A
authors.initials: PA
authors.lastname: Tyrakis
authors.forename: Hui
authors.initials: H
authors.lastname: Hong
authors.forename: Yuhui
authors.initials: Y
authors.lastname: Sun
authors.forename: Markiyan
authors.initials: M
authors.lastname: Samborskyy
authors.forename: Kohei
authors.initials: K
authors.lastname: Kamiya
authors.forename: Peter F
authors.initials: PF
authors.lastname: Leadlay
mesh_terms: D053898:Biosynthetic Pathways / Q000235:genetics*; D015698:Genomic Library; D008968:Molecular Conformation; D009154:Mutation; D048630:Polyketide Synthases / Q000235:genetics / Q000378:metabolism*; D011714:Pyrans / Q000737:chemistry / Q000378:metabolism*; D013302:Streptomyces / Q000201:enzymology / Q000235:genetics* / Q000378:metabolism; D000095662:Polyether Polyketides
chemical_list: D048630:Polyketide Synthases; D011714:Pyrans; C010327:salinomycin; D000095662:Polyether Polyketides