title: Clinical and radiological observation in a surgical series of 36 cases of fibrous dysplasia of the skull.
abstract: OBJECTIVE
  To describe the clinical and radiological findings in a consecutive series of patients diagnosed with fibrous dysplasia of the skull.
  
  
  METHODS
  A retrospective analysis of collected data for 36 patients with histopathologically confirmed fibrous dysplasia involving the skull is presented. The demographic data, clinical presentation, radiographic characteristics, and the management of these patients were reviewed.
  
  
  RESULTS
  All 36 patients in this review were diagnosed with fibrous dysplasia involving at least part of the skull. In this study, the most commonly involved area of the skull was the frontal bone (52.78% of patients). The next most common area of skull was the temporal bone (30.56% of patients), followed by the sphenoid bone (25% of patients), the parietal bone (19.44% of patients), and orbital bone (13.89% of patients). The principal clinical presentation included headache, local lump, exophthalmos, visual disorder, cranial nerve paralysis, and facial malformation. These patients were treated by surgical treatment, and several of our patients underwent various degrees of reconstruction to optimize function.
  
  
  CONCLUSIONS
  Effective surgical treatment may improve the short-term outcome in these patients, and a "tailored" surgical approach is necessary.
authors.affiliation: Department of Neurosurgery, Wuhan General Hospital of Guangzhou Military Command, 627 Wuluo Avenue, Wuhan, Hubei 430070, PR China. mingjuncai@hotmail.com
authors.forename: MingJun
authors.initials: M
authors.lastname: Cai
authors.forename: LianTing
authors.initials: L
authors.lastname: Ma
authors.forename: GuoZheng
authors.initials: G
authors.lastname: Xu
authors.forename: Peter
authors.initials: P
authors.lastname: Gruen
authors.forename: Jun
authors.initials: J
authors.lastname: Li
authors.forename: Ming
authors.initials: M
authors.lastname: Yang
authors.forename: Li
authors.initials: L
authors.lastname: Pan
authors.forename: HanFeng
authors.initials: H
authors.lastname: Guan
authors.forename: Gang
authors.initials: G
authors.lastname: Chen
authors.forename: Jie
authors.initials: J
authors.lastname: Gong
authors.forename: JunMing
authors.initials: J
authors.lastname: Hu
authors.forename: ShangZheng
authors.initials: S
authors.lastname: Qin
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D005157:Facial Pain / Q000209:etiology; D005260:Female; D005357:Fibrous Dysplasia of Bone / Q000473:pathology* / Q000601:surgery / Q000628:therapy*; D005500:Follow-Up Studies; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D019635:Neurosurgical Procedures; D012189:Retrospective Studies; D012886:Skull / Q000473:pathology* / Q000601:surgery; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D055815:Young Adult