title: Epidemiology of syphilis-related hospitalisations in Spain between 1997 and 2006: a retrospective study.
abstract: Objective In order to illustrate the important public health impact of syphilis, which is a preventable infection, the epidemiology of syphilis-related hospitalisations in Spain was studied over a 10-year period.  Methods A retrospective study was conducted using the National Epidemiological Surveillance System for Hospital Data (Minimum Data Set). All hospitalisations due to syphilis infection in any diagnostic position (ICD-9-CM 090-097) between 1997 and 2006 were analysed, according to the Spanish version of the International Classification of Diseases, ninth revision (ICD-9-CM).  Results There were 9556 hospitalisations associated with syphilis in Spain. The hospitalisation rate was 2.33 per 100 000 population, the mortality rate was 0.07 per 100 000 population and the lethality was 3.17%. The hospitalisation rate increased significantly after 2000 and was higher in men.  Conclusion Syphilis remains a major public health problem because of both potential complications and its close association with HIV infection. It is necessary to promote early diagnosis, ensure treatment in patients with syphilis and emphasise health promotion and prevention programmes.
authors.affiliation: Department of Preventive Medicine and Public Health and Medical Immunology and Microbiology, Rey Juan Carlos University, Madrid, Spain.
authors.forename: Laura
authors.initials: L
authors.lastname: García-García
authors.forename: M Carmen
authors.initials: MC
authors.lastname: Ariza-Megía
authors.forename: Alba
authors.initials: A
authors.lastname: González-Escalada
authors.forename: Alejandro
authors.initials: A
authors.lastname: Alvaro-Meca
authors.forename: Angel
authors.initials: A
authors.lastname: Gil-Demiguel
authors.forename: Ruth
authors.initials: R
authors.lastname: Gil-Prieto
references.citation: Euro Surveill. 2004 Dec;9(12):25-7
references.pmid: 15677850
references.citation: Sex Transm Dis. 2005 Apr;32(4):220-6
references.pmid: 15788919
references.citation: MMWR Morb Mortal Wkly Rep. 2006 Mar 17;55(10):269-73
references.pmid: 16543880
references.citation: Sex Transm Infect. 2004 Aug;80(4):255-63
references.pmid: 15295121
references.citation: Euro Surveill. 2004 Dec;9(12):11-4
references.pmid: 15677854
references.citation: Sex Transm Dis. 2007 Aug;34(8):592-7
references.pmid: 17325622
references.citation: Clin Infect Dis. 2009 Nov 15;49(10):1505-11
references.pmid: 19842977
references.citation: N Engl J Med. 2010 May 6;362(18):1658-61
references.pmid: 20445179
references.citation: Sex Transm Dis. 2005 Oct;32(10 Suppl):S4-10
references.pmid: 16205291
references.citation: Med Clin (Barc). 2006 Jan 28;126(3):94-6
references.pmid: 16472482
references.citation: Curr Opin Infect Dis. 2007 Feb;20(1):54-9
references.pmid: 17197882
references.citation: Sex Transm Dis. 2008 Apr;35(4):393-7
references.pmid: 18362861
references.citation: Euro Surveill. 2008 Dec 11;13(50):
references.pmid: 19087867
references.citation: Sex Transm Dis. 2004 May;31(5):317-21
references.pmid: 15107636
references.citation: Med J Aust. 2005 Aug 15;183(4):179-83
references.pmid: 16097913
references.citation: Euro Surveill. 2008 Dec 11;13(50):
references.pmid: 19087866
references.citation: Sex Transm Dis. 2002 May;29(5):277-84
references.pmid: 11984444
references.citation: Sex Transm Infect. 2006 Feb;82(1):1
references.pmid: 16461590
references.citation: Sex Transm Dis. 2005 Oct;32(10 Suppl):S11-8
references.pmid: 16205286