title: [Progress in co-culture and differentiation in adipose-derived stem cells: a review].
abstract: Stem cells can be differentiated into many kinds of somatic cells under defined culture conditions. In addition, the homing possess can be partially imitated by co-culture of stem cells with mature somatic cells. Regarding the importance of clinical application of adipose-derived stem cells (ADSCs), our review first introduced the sources and signs of ADSCs, and then the current knowledge of ADSCs co-culture technology, including drug and chemical induced culture, two-dimensional (2D) and three-dimensional (3D) co-culture, mechanisms of ADSCs differentiation, and application development in recent years in details. Finally, we also addressed prospects of ADSCs.
authors.affiliation: Murad Research Center for Modernized Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
authors.forename: Xuqiang
authors.initials: X
authors.lastname: Nie
authors.forename: Huaihong
authors.initials: H
authors.lastname: Chen
authors.forename: Ning
authors.initials: N
authors.lastname: Tang
authors.forename: Ka
authors.initials: K
authors.lastname: Bian
mesh_terms: D000273:Adipose Tissue / Q000166:cytology*; D000818:Animals; D002454:Cell Differentiation / Q000187:drug effects*; D002478:Cells, Cultured; D018920:Coculture Techniques / Q000379:methods; D006801:Humans; D013234:Stem Cells / Q000166:cytology*; D023822:Tissue Engineering