title: [Association of visceral adiposity with urinary albumin excretion in type 2 diabetics].
abstract: OBJECTIVE
  To decipher the association of visceral adiposity (VA) with 24-hour urinary albumin excretion (24 h-UAE) in type 2 diabetics.
  
  
  METHODS
  We collected the clinical data, VA, subcutaneous adiposity (SA), 24 h-UAE, blood lipids, fasting blood glucose, glycosylated hemoglobin, insulin and tumor necrosis factor (TNF)-α of type 2 diabetic inpatients at our hospital. According to the quartile of VA, the subjects were divided into 4 groups. And their profiles were compared with regards to the level of 24 h-UAE and the incidence of heavy proteinuria. And their relative intensities and the linear relationship of VA and lg (24 h-UAE) were analyzed.
  
  
  RESULTS
  lg (24 h-UAE) of groups C and D was larger than that of groups A and B. With the rising level of VA, the prevalence of heavy proteinuria increased. A moderate correlation existed between VA and lg (24 h-UAE) (r = 0.51). lg (24 h-UAE) increased 0.26 units as VA expanded 100 cm(2), i.e. 0.15 units after relative factor adjusting. After gender and triglyceride adjusting, the odds ratio of heavy albuminuria in group C was 2.75 versus that in group A. And the OR was 3.87 in group D.
  
  
  CONCLUSIONS
  Expansion of VA is a risk factor for an elevated risk of 24 h-UAE. With the expansion of VA, the prevalence of heavy albuminuria increases.
authors.affiliation: Department of Endocrinology, Third Affiliated Hospital, Hebei Medical University, Shijiazhuang 050051, China.
authors.forename: Sha
authors.initials: S
authors.lastname: Zhai
authors.forename: Zhan-jian
authors.initials: ZJ
authors.lastname: Wang
mesh_terms: D034841:Abdominal Cavity / Q000473:pathology*; D000328:Adult; D000368:Aged; D000419:Albuminuria / Q000378:metabolism*; D003924:Diabetes Mellitus, Type 2 / Q000473:pathology* / Q000652:urine*; D005260:Female; D006801:Humans; D050152:Intra-Abdominal Fat / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D050507:Subcutaneous Fat, Abdominal / Q000473:pathology