title: Association between a single  nucleotide  polymorphism in the bovine chemerin gene and carcass  traits in Qinchuan cattle.
abstract: Qinchuan  is a red or yellow draft and beef breed in China. In order to identify a  predictor of carcass traits on the basis of associations between carcass traits  and gene polymorphism, variation in the bovine chemerin gene was investigated  using PCR-single-strand conformational polymorphism and DNA sequencing. An SNP  of A868G located in exon 2 of the Bos taurus chemerin gene was detected  in 716 samples of six breeds (Jiaxian red, Luxi, Nan yang, Qinchuan, Simmental  and Luxi crossbred steers, and Xia'nan), all in China, and three genotypes (AA,  AG and GG) were found. Based on the χ(2) test,  the AA/AG/GG genotype frequencies of all six breeds were found to be in  Hardy-Weinberg equilibrium. A possible association of A868G with some carcass  traits was investigated in 106 Qinchuan cattle. Animals with the AG genotype  were found to have significantly lower mean loin eye area and meat tenderness  compared to those with the AA and GG genotypes. However, there was no  significant association between any individual haplotype and backfat thickness,  water holding capacity or marbling score. We suggest that A868G could be used  as a molecular marker in marker-assisted selection for carcass traits.
authors.affiliation: College of Animal Science and Technology, Northwest A & F University, Yangling, Shaanxi, PR China.
authors.forename: W Q
authors.initials: WQ
authors.lastname: Tian
authors.forename: H C
authors.initials: HC
authors.lastname: Wang
authors.forename: F B
authors.initials: FB
authors.lastname: Song
authors.forename: L S
authors.initials: LS
authors.lastname: Zan
authors.forename: H
authors.initials: H
authors.lastname: Wang
authors.forename: H B
authors.initials: HB
authors.lastname: Wang
authors.forename: Y P
authors.initials: YP
authors.lastname: Xin
authors.forename: J A
authors.initials: JA
authors.lastname: Ujan
mesh_terms: D000818:Animals; D049628:Body Size / Q000235:genetics*; D001947:Breeding; D002417:Cattle / Q000235:genetics*; D018925:Chemokines / Q000235:genetics*; D002681:China; D005091:Exons / Q000235:genetics*; D005819:Genetic Markers; D005838:Genotype; D020641:Polymorphism, Single Nucleotide; D040641:Quantitative Trait Loci / Q000502:physiology*; D012863:Skeleton
chemical_list: D018925:Chemokines; D005819:Genetic Markers