title: SABIO-RK--database for biochemical reaction kinetics.
abstract: SABIO-RK (http://sabio.h-its.org/) is a web-accessible database storing comprehensive information about biochemical reactions and their kinetic properties. SABIO-RK offers standardized data manually extracted from the literature and data directly submitted from lab experiments. The database content includes kinetic parameters in relation to biochemical reactions and their biological sources with no restriction on any particular set of organisms. Additionally, kinetic rate laws and corresponding equations as well as experimental conditions are represented. All the data are manually curated and annotated by biological experts, supported by automated consistency checks. SABIO-RK can be accessed via web-based user interfaces or automatically via web services that allow direct data access by other tools. Both interfaces support the export of the data together with its annotations in SBML (Systems Biology Markup Language), e.g. for import in modelling tools.
authors.affiliation: Scientific Databases and Visualization Group, Heidelberg Institute for Theoretical Studies, gGmbH, Schloss-Wolfsbrunnenweg 35, 69118 Heidelberg, Germany. Ulrike.Wittig@h-its.org
authors.forename: Ulrike
authors.initials: U
authors.lastname: Wittig
authors.forename: Renate
authors.initials: R
authors.lastname: Kania
authors.forename: Martin
authors.initials: M
authors.lastname: Golebiewski
authors.forename: Maja
authors.initials: M
authors.lastname: Rey
authors.forename: Lei
authors.initials: L
authors.lastname: Shi
authors.forename: Lenneke
authors.initials: L
authors.lastname: Jong
authors.forename: Enkhjargal
authors.initials: E
authors.lastname: Algaa
authors.forename: Andreas
authors.initials: A
authors.lastname: Weidemann
authors.forename: Heidrun
authors.initials: H
authors.lastname: Sauer-Danzwith
authors.forename: Saqib
authors.initials: S
authors.lastname: Mir
authors.forename: Olga
authors.initials: O
authors.lastname: Krebs
authors.forename: Meik
authors.initials: M
authors.lastname: Bittkowski
authors.forename: Elina
authors.initials: E
authors.lastname: Wetsch
authors.forename: Isabel
authors.initials: I
authors.lastname: Rojas
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Müller
mesh_terms: D001669:Biochemical Phenomena; D016208:Databases, Factual; D004798:Enzymes / Q000378:metabolism; D020407:Internet; D007700:Kinetics; D014584:User-Computer Interface
chemical_list: D004798:Enzymes
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