title: [Observation on the anti-stress effect of acupuncture-assisted anesthesia for puhnlmonary lobectomy patients].
abstract: OBJECTIVE
  To observe the anti-stress effect of acupuncture-assisted anesthesia in patients undergoing pulmonary lobectomy.
  
  
  METHODS
  A randomized, controlled, single-blind clinical trial was conducted in the present study. A total of 48 patients undergoing pulmonary lobectomy were randomized into regular general anesthesia (RGA), general anesthesia combined with 2 Hz electroacupuncture (EA) (GA+2 Hz-EA), general anesthesia combined with 2 Hz/100 Hz EA (GA+2 Hz/100 Hz-EA), and GA + 100 Hz-EA groups (n=12). EA (1-3 mA) was applied to bilateral Houxi (SI 3), Zhigou (SJ 6), Neiguan (PC 6) and Hegu (LI 4) for 30 min, followed by general anesthesia with midazolam (0.05 mg/kg), fentanyl (5 microg/kg), propofol (2 mg/kg), and vecuronium (0.1 mg/kg). The dosages of the anesthetics, heart rate (HR), systolic blood pressure (SBP), and bispectral index (BIS) of electroencephalogam during general anesthesia were recorded. Plasma adrenaline and cortisol concentrations were assayed by radioimmunoassay.
  
  
  RESULTS
  In comparison with the RGA group, the dosages of supplementary propofol and fentanyl in both GA + 2 Hz-EA and GA + 100 Hz-EA groups,and that of propofol in the GA+2 Hz/100 Hz-EA group were decreased significantly (P < 0.05, P < 0.01). Compared to the RGA group, both HR and SBP values during trachea extubation in the GA+ 2 Hz/100 Hz-EA and GA + 100 Hz-EA groups were significantly lower (P < 0.01, P < 0.05). No significant differences were found between the GA+2 Hz/100 Hz-EA and RGA groups in the supplementary dose of fentanyl, between the GA+2 Hz-EA and RGA groups in HR and SBP values during trachea extubation, among the 4 groups in HR and SBP values before trachea extubation and in plasma adrenaline and cortisol levels (P > 0.05).
  
  
  CONCLUSIONS
  Acupuncture-assisted anesthesia can decrease the dosage of general anesthetics, and effectively restrain cardiovascular stress reaction during trachea extubation in pulmonery lobectomy patients.
authors.affiliation: Shuguang Hospital Affiliated to Shanghai University of Chinese Medicine, Shanghai 201203, China. fuguoqiang201010@hotmail.com
authors.forename: Guo-qiang
authors.initials: GQ
authors.lastname: Fu
authors.forename: Jia
authors.initials: J
authors.lastname: Zhou
authors.forename: Qiu-yu
authors.initials: QY
authors.lastname: Tong
authors.forename: Yu-ming
authors.initials: YM
authors.lastname: Zhu
authors.forename: Wen
authors.initials: W
authors.lastname: Ma
authors.forename: Hong
authors.initials: H
authors.lastname: Zhou
authors.forename: Wei-dong
authors.initials: WD
authors.lastname: Shen
mesh_terms: D015667:Acupuncture Analgesia; D015669:Acupuncture Points; D000328:Adult; D000368:Aged; D000768:Anesthesia, General; D001794:Blood Pressure; D005260:Female; D006339:Heart Rate; D006801:Humans; D008168:Lung / Q000601:surgery*; D008171:Lung Diseases / Q000503:physiopathology / Q000601:surgery*; D008297:Male; D008875:Middle Aged