title: Motor and non-motor predictors of illness-related distress in Parkinson's disease.
abstract: OBJECTIVE
  To identify motor and non-motor symptoms independently associated with distress in Parkinson's disease (PD).
  
  
  METHODS
  Clinical and patient-reported data from 118 people with PD (mean age and PD-duration, 64 and 8 years) were analyzed regarding associations with patient-reported distress using multiple regressions (controlling for age).
  
  
  RESULTS
  Non-motor symptoms independently associated with distress were pain, fatigue, sleep, depression and anxiety (R(2), 0.81). The only significant motor aspect was mobility (R(2), 0.31). When considering both motor and non-motor symptoms, fatigue, pain, depression and sleep showed independent associations with distress (R(2), 0.76).
  
  
  CONCLUSIONS
  Distress in PD is primarily associated with non-motor features.
authors.affiliation: Department of Health Sciences, Lund University, Lund, Sweden.
authors.forename: Catharina
authors.initials: C
authors.lastname: Sjödahl Hammarlund
authors.forename: Peter
authors.initials: P
authors.lastname: Hagell
authors.forename: Maria H
authors.initials: MH
authors.lastname: Nilsson
mesh_terms: D001007:Anxiety / Q000453:epidemiology / Q000209:etiology; D003430:Cross-Sectional Studies; D003863:Depression / Q000453:epidemiology / Q000209:etiology; D005221:Fatigue / Q000453:epidemiology / Q000209:etiology; D006801:Humans; D008875:Middle Aged; D009043:Motor Activity / Q000502:physiology; D010146:Pain / Q000453:epidemiology / Q000209:etiology; D010300:Parkinson Disease / Q000150:complications* / Q000523:psychology*