title: Interstitial granulomatous dermatitis: another clinical variant.
abstract: A 70-year-old female patient presented with an eruption consisting of symmetrically distributed erythematous papules around the umbilicus 1 month after the cessation of adalimumab for the treatment of rheumatoid arthritis. Biopsy of a papule showed an interstitial granulomatous infiltrate in the dermis, without deposition of mucin. The lesions cleared only after re-initiation of treatment 2 months later. Interstitial granulomatous dermatitis is thought to be a distinct histopathological pattern, either drug induced or associated with rheumatoid arthritis or autoimmune collagen diseases. In our case, there was a distinct clinical presentation of interstitial granulomatous dermatitis, composed of symmetrically distributed indurated papules around the umbilicus as well as a mild granulomatous reaction pattern.
authors.affiliation: 2nd Dermatology Department, Aristotle University School of Medicine, Papageorgiou Hospital, Thessaloniki, Greece.
authors.forename: Aikaterini
authors.initials: A
authors.lastname: Patsatsi
authors.forename: Aikaterini
authors.initials: A
authors.lastname: Kyriakou
authors.forename: Eva
authors.initials: E
authors.lastname: Triantafyllidou
authors.forename: Dimitrios
authors.initials: D
authors.lastname: Sotiriadis
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