title: Gastrointestinal stromal tumor of the stomach in a child with a 3-year follow-up period-Case report.
abstract: We report a case of a nine-year-old boy with a 4-week history of general fatigue, loss of appetite, vomits and hematemesis. Laboratory evaluation revealed a hemoglobin level of 4.4 g/dl. After a transfusion of packed red blood cells the patient underwent an esophagogastroduodenoscopy, which showed a smooth, rounded 6-8 cm submucosal lesion with a central depression with ulceration and active bleeding in the cardia extending to the fundus.Computed tomography (CT) of the chest, abdomen and pelvis showed a large mass originating from the gastric wall but not infiltrating surrounding organs, approximately 8.0 cm × 7.0 cm × 5 cm. Despite the tumor size, no metastases were diagnosed. The patient underwent a total gastrectomy in an en-bloc resection including the distal part of the esophagus (3 cm) and omentum with oncologic margins. Reconstruction was performed with a mediastinal end-to-side esophago-jejunal anastomosis. Immunehistochemic confirmed GIST. He remains well without evidence of disease after 36 months of follow-up with a multiprofessional team.
authors.affiliation: Unit of Pediatric Surgery of Hospital of Clinics and Department of Surgery of the Federal University of Minas Gerais, Av. Professor Alfredo Balena, n  110, CEP 30130-100, Belo Horizonte, Minas Gerais, Brazil.
authors.forename: Marcelo Eller
authors.initials: ME
authors.lastname: Miranda
authors.forename: Luiz Ronaldo
authors.initials: LR
authors.lastname: Alberti
authors.forename: Edson Samesima
authors.initials: ES
authors.lastname: Tatsuo
authors.forename: Clécio
authors.initials: C
authors.lastname: Piçarro
authors.forename: Marcelo
authors.initials: M
authors.lastname: Rausch
references.citation: J Pediatr Surg. 2007 Jul;42(7):1302-5
references.pmid: 17618903
references.citation: Am J Surg Pathol. 2005 Oct;29(10):1373-81
references.pmid: 16160481
references.citation: Pediatr Radiol. 2006 Nov;36(11):1212-4
references.pmid: 16969663
references.citation: Pediatr Surg Int. 2005 Nov;21(11):914-7
references.pmid: 16240136
references.citation: J Pediatr Surg. 2004 Oct;39(10):1495-9
references.pmid: 15486893
references.citation: J Pediatr Hematol Oncol. 2005 Apr;27(4):179-87
references.pmid: 15838387
references.citation: Pediatr Dev Pathol. 2005 Nov-Dec;8(6):685-9
references.pmid: 16328663