title: The laboratory of clinical virology in monitoring patients undergoing monoclonal antibody therapy.
abstract: The relevant efficacy of monoclonal antibodies (mAbs) has resulted in the successful treatment of several diseases, although susceptibility to infections remains a major problem. This review summarizes aspects of the literature regarding viral infections and mAbs, specifically addressing the risk of infection/reactivation, the measures that can reduce this risk, and the role played by the laboratory of clinical virology in monitoring patients undergoing mAb therapy.
authors.affiliation: Virology Unit, University-Hospital San Giovanni Battista di Torino, Torino, Italy. rossana.cavallo@unito.it
authors.forename: R
authors.initials: R
authors.lastname: Cavallo
mesh_terms: D000911:Antibodies, Monoclonal / Q000009:adverse effects / Q000627:therapeutic use*; D019411:Clinical Laboratory Techniques / Q000379:methods*; D016903:Drug Monitoring / Q000379:methods*; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects / Q000627:therapeutic use*; D009894:Opportunistic Infections / Q000139:chemically induced / Q000175:diagnosis*; D014773:Virology / Q000379:methods*; D014775:Virus Activation; D014777:Virus Diseases / Q000139:chemically induced / Q000175:diagnosis*
chemical_list: D000911:Antibodies, Monoclonal; D007166:Immunosuppressive Agents