title: [Severe pulmonary embolism in a young marijuana smoker].
abstract: It is a popular belief, that marijuana smoking is not harmful to health. Some publications, however, suggest its possible association with mental, respiratory and cardiovascular complications, but not with venous thromboembolism. The authors describe a case of severe pulmonary embolism in a mildly obese, 22 year-old marijuana and tobacco smoker. After thrombolysis, rapid haemodynamic improvement was observed, contrary to slow regression of concomitant deep vein thrombosis during anticoagulation with warfarin. Toxycologic assessment of urine cannabinols was positive for two months. In trombophilia screening only moderate hyperhomocysteinaemia (not related to MTHFR C667T polymorphism) was found.
authors.affiliation: Oddział Chorób Wewnętrznych, Szpital im. J. Strusia, Poznań. welikowski@wp.pl
authors.forename: Waldemar
authors.initials: W
authors.lastname: Elikowski
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Małek
authors.forename: Jolanta
authors.initials: J
authors.lastname: Kurosz
authors.forename: Alina
authors.initials: A
authors.lastname: Podkowińska
authors.forename: Magdalena
authors.initials: M
authors.lastname: Lukowiak-Głębocka
authors.forename: Krystyna
authors.initials: K
authors.lastname: Zawilska
mesh_terms: D002188:Cannabis / Q000009:adverse effects*; D013759:Dronabinol / Q000009:adverse effects*; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D006213:Hallucinogens / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008385:Marijuana Smoking / Q000009:adverse effects*; D011655:Pulmonary Embolism / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology*; D015912:Thrombolytic Therapy / Q000379:methods; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D014463:Ultrasonography; D055815:Young Adult
chemical_list: D005343:Fibrinolytic Agents; D006213:Hallucinogens; D013759:Dronabinol