title: Clinical evaluation of Soothing Gan and invigorating Pi acupuncture treatment on diarrhea-predominant irritable bowel syndrome.
abstract: OBJECTIVE
  To explore the effect of Soothing Gan and invigorating Pi (SGIP) acupuncture treatment on the clinical symptoms and quality of life (QOL) in patients with diarrhea-predominant irritable bowel syndrome (IBS-D).
  
  
  METHODS
  With a single-blinded randomized control study adopted, 63 patients who met the inclusion criteria were assigned by a random number table to two groups, 31 in the treatment group and 32 in the drug control group. The treatment group received SGIP acupuncture therapy; while the control group was treated orally with pinaverium bromide. The treatment duration of both groups was 28 days. The clinical efficacy was evaluated and compared by scoring patient's symptom and QOL.
  
  
  RESULTS
  A significant difference was found by variance analysis in efficacies between the two groups (P<0.01), shown as the quicker initiation of effect (P<0.05) and the more evident clinical improvement in symptoms along the increase in treatment duration, as well as the more significant elevation of QOL in the acupuncture treatment group (P<0.01). SGIP displayed its superiority especially in improving dysphoria, conflict behavior, dietary restrictions, and social responses.
  
  
  CONCLUSIONS
  SGIP acupuncture treatment could effectively alleviate the degree and frequency of symptoms' attack in IBS-D patients, such as abdominal pain, diarrhea, abdominal distension, etc., markedly relieve the tenesmic sensation, with the efficacy better than that of pinaverium bromide, showing a preponderance in improving patient's QOL.
authors.affiliation: Department of Acupuncture and Rehabilitation, First Hospital Affiliated to Nanjing University of Traditional Chinese Medicine, Nanjing, China. drjhsun@sina.com
authors.forename: Jian-hua
authors.initials: JH
authors.lastname: Sun
authors.forename: Xiao-liang
authors.initials: XL
authors.lastname: Wu
authors.forename: Chen
authors.initials: C
authors.lastname: Xia
authors.forename: Lu-zhou
authors.initials: LZ
authors.lastname: Xu
authors.forename: Li-xia
authors.initials: LX
authors.lastname: Pei
authors.forename: Hao
authors.initials: H
authors.lastname: Li
authors.forename: Guang-Yan
authors.initials: GY
authors.lastname: Han
mesh_terms: D015670:Acupuncture Therapy / Q000009:adverse effects / Q000379:methods*; D000293:Adolescent; D000328:Adult; D003967:Diarrhea / Q000150:complications* / Q000628:therapy*; D005260:Female; D006801:Humans; D043183:Irritable Bowel Syndrome / Q000150:complications* / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D010352:Patient Dropouts; D011788:Quality of Life; D016896:Treatment Outcome; D055815:Young Adult
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