title: MQD--multiplex-quadrature detection in multi-dimensional NMR.
abstract: With multiplex-quadrature detection (MQD) the tasks of coherence selection and quadrature separation in N-dimensional heteronuclear NMR experiments are merged. Thus the number of acquisitions required to achieve a desired resolution in the indirect dimensions is significantly reduced. The minimum number of transients per indirect data point, which have to be combined to give pure-phase spectra, is thus decreased by a factor (3/4)(N-1). This reduction is achieved without adjustable parameters. We demonstrate the advantage by MQD 3D HNCO and HCCH-TOCSY spectra affording the same resolution and the same per-scan sensitivity as standard phase-cycled ones, but obtained in only 56 % of the usual time and by resolution improvements achieved in the same amount of time.
authors.affiliation: Institute of Organic Chemistry, Johannes Kepler University Linz, Altenberger Str. 69, 4040 Linz, Austria.
authors.forename: Judith
authors.initials: J
authors.lastname: Schlagnitweit
authors.forename: Michaela
authors.initials: M
authors.lastname: Horničáková
authors.forename: Gerhard
authors.initials: G
authors.lastname: Zuckerstätter
authors.forename: Norbert
authors.initials: N
authors.lastname: Müller
mesh_terms: D000465:Algorithms; D009682:Magnetic Resonance Spectroscopy
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