title: Modular synthesis of functionalized bis-bispidine tetraazamacrocycles.
abstract: An effective synthesis is reported for the construction of highly rigid and preorganized bis-bispidine tetraazamacrocycles bearing either identical or different functionalities. Using essential building blocks derived from N-Boc-N'-allylbispidinone, the modular approach facilitates independent incorporation of the functional groups to the macrocyclic framework as well as selective derivatization of one functionality in the presence of another.
authors.affiliation: Department of Chemistry and Biochemistry, University of Windsor, Windsor, Ontario, Canada N9B 3P4. zhuowang@uwindsor.ca
authors.forename: Zhuo
authors.initials: Z
authors.lastname: Wang
authors.forename: Erin J
authors.initials: EJ
authors.lastname: Miller
authors.forename: Samantha J
authors.initials: SJ
authors.lastname: Scalia