title: The potential of antimicrobial peptides as biocides.
abstract: Antimicrobial peptides constitute a diverse class of naturally occurring antimicrobial molecules which have activity against a wide range of pathogenic microorganisms. Antimicrobial peptides are exciting leads in the development of novel biocidal agents at a time when classical antibiotics are under intense pressure from emerging resistance, and the global industry in antibiotic research and development stagnates. This review will examine the potential of antimicrobial peptides, both natural and synthetic, as novel biocidal agents in the battle against multi-drug resistant pathogen infections.
authors.affiliation: Ward Biotech Ltd., Glasdrummann, Milltown, Monaghan, Ireland.
authors.forename: Garry
authors.initials: G
authors.lastname: Laverty
authors.forename: Sean P
authors.initials: SP
authors.lastname: Gorman
authors.forename: Brendan F
authors.initials: BF
authors.lastname: Gilmore
mesh_terms: D023181:Antimicrobial Cationic Peptides / Q000737:chemistry* / Q000378:metabolism / Q000494:pharmacology; D001419:Bacteria / Q000378:metabolism; D002462:Cell Membrane / Q000378:metabolism; D002473:Cell Wall / Q000378:metabolism; D004202:Disinfectants / Q000737:chemistry* / Q000378:metabolism / Q000494:pharmacology; D015195:Drug Design; D024901:Drug Resistance, Multiple, Bacterial / Q000187:drug effects; D006461:Hemolysis / Q000187:drug effects; D055666:Lipopeptides / Q000737:chemistry / Q000494:pharmacology
chemical_list: D023181:Antimicrobial Cationic Peptides; D004202:Disinfectants; D055666:Lipopeptides
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