title: (5E)-5-(4-Meth-oxy-benzyl-idene)-2-(piperidin-1-yl)-1,3-thia-zol-4(5H)-one.
abstract: In the title compound, C(16)H(18)N(2)O(2)S, the piperidine ring adopts a chair conformation. The central 4-thia-zolidinone ring makes dihedral angles of 12.01 (7) and 51.42 (9)°, respectively, with the benzene ring and the least-squares plane of the piperidine ring. An intra-molecular C-H⋯S hydrogen bond stabilizes the mol-ecular structure and generates an S(6) ring motif. In the crystal, mol-ecules are linked into a tape along the c axis by inter-molecular C-H⋯O hydrogen bonds.
authors.forename: Hoong-Kun
authors.initials: HK
authors.lastname: Fun
authors.forename: Chin Sing
authors.initials: CS
authors.lastname: Yeap
authors.forename: Prajwal L
authors.initials: PL
authors.lastname: Lobo
authors.forename: D Jagadeesh
authors.initials: DJ
authors.lastname: Prasad
authors.forename: Boja
authors.initials: B
authors.lastname: Poojary
references.citation: Acta Crystallogr D Biol Crystallogr. 2009 Feb;65(Pt 2):148-55
references.pmid: 19171970
references.citation: Eur J Med Chem. 2009 Apr;44(4):1396-404
references.pmid: 19000643
references.citation: Eur J Med Chem. 2007 May;42(5):641-8
references.pmid: 17303290
references.citation: Bioorg Med Chem Lett. 2008 Apr 1;18(7):2250-5
references.pmid: 18358718
references.citation: Acta Crystallogr A. 2008 Jan;64(Pt 1):112-22
references.pmid: 18156677
references.citation: J Med Chem. 2008 Sep 11;51(17):5221-8
references.pmid: 18702480