title: Removal of oxytetracycline (OTC) in a synthetic pharmaceutical wastewater by a sequential anaerobic multichamber bed reactor (AMCBR)/completely stirred tank reactor (CSTR) system: biodegradation and inhibition kinetics.
abstract: An anaerobic multichamber bed reactor (AMCBR) was effective in removing both molasses-chemical oxygen demand (COD), and the antibiotic oxytetracycline (OTC). The maximum COD and OTC removals were 99% in sequential AMCBR/completely stirred tank reactor (CSTR) at an OTC concentration of 300 mg L(-1). 51%, 29% and 9% of the total volatile fatty acid (TVFA) was composed of acetic, propionic acid and butyric acids, respectively. The OTC loading rates at between 22.22 and 133.33 g OTC m(-3) d(-1) improved the hydrolysis of molasses-COD (k), the maximum specific utilization of molasses-COD (k(mh)) and the maximum specific utilization rate of TVFA (k(TVFA)). The direct effect of high OTC loadings (155.56 and -177.78 g OTC m(-3) d(-1)) on acidogens and methanogens were evaluated with Haldane inhibition kinetic. A significant decrease of the Haldane inhibition constant was indicative of increases in toxicity at increasing loading rates.
authors.affiliation: Dokuz Eylul University Engineering Faculty, Environmental Engineering Department, Buca Kaynaklar Campus, 35160 Izmir, Turkey. delya.sponza@deu.edu.tr
authors.forename: Delia Teresa
authors.initials: DT
authors.lastname: Sponza
authors.forename: Hakan
authors.initials: H
authors.lastname: Çelebi
mesh_terms: D001421:Bacteria, Anaerobic / Q000378:metabolism*; D061249:Batch Cell Culture Techniques / Q000295:instrumentation*; D019149:Bioreactors / Q000382:microbiology*; D003198:Computer Simulation; D004867:Equipment Design; D019544:Equipment Failure Analysis; D007220:Industrial Waste / Q000517:prevention & control; D008954:Models, Biological; D010118:Oxytetracycline / Q000302:isolation & purification / Q000378:metabolism*; D012399:Rotation; D014867:Water / Q000737:chemistry; D014871:Water Microbiology; D014874:Water Pollutants, Chemical / Q000302:isolation & purification / Q000378:metabolism*; D018508:Water Purification / Q000379:methods*
chemical_list: D007220:Industrial Waste; D014874:Water Pollutants, Chemical; D014867:Water; D010118:Oxytetracycline