title: [Serological profile of immigrant pregnant women against HIV, HBV, HCV, rubella, Toxoplasma gondii, Treponema pallidum, and Trypanosoma cruzi].
abstract: BACKGROUND
  The increase in immigration is changing the prevalence of mother to child infectious diseases. Our aim is to determine the serological profile of foreign pregnant women against these infections.
  
  
  METHODS
  A retrospective cross sectional study was performed in a tertiary hospital from Madrid between August 2007 and October 2008. The seroprevalence against HIV, HBV, HCV, rubeola, T. gondii, T. pallidum and T. cruzi was determined in every pregnant immigrant, as well as in a representative group of Spanish pregnant women.
  
  
  RESULTS
  A total of 2526 immigrant and 157 Spanish pregnant women were studied. None of the Spanish and 0.5% of the foreigners showed antibodies against HIV; 18.9% of them were Sub-Saharan women. Antigen HBs was detected in 2% of the immigrant women and in 1.1% of the Spanish women. Asian women had the highest rate of type B Hepatitis (10.9%). There was 0.9% of type C Hepatitis among the immigrants and 1% among the Spanish. Within the cases with RPR ≥ 1/8, 1.6% were immigrants, most of whom were Latin American. Thirty-one per cent of the immigrants showed antibodies against T. gondii (37.5% from Central America, 2.5% from the Far East). More than 95% of the Spanish women had antibodies against Rubella, this being lower in the rest of the areas (75.5% in Sub-Saharan Africa). T. cruzi infection was detected in 12.1% of the Bolivian women studied.
  
  
  CONCLUSIONS
  The prevalence of mother-to-child transmitted infections depends on the origin of pregnant women. Knowledge of these differences may lead to improved control these diseases.
authors.affiliation: Servicio de Pediatría, Hospital Universitario Clínico San Carlos, Madrid, España. bsantiagogarcia@hotmail.com
authors.forename: Begoña
authors.initials: B
authors.lastname: Santiago
authors.forename: Daniel
authors.initials: D
authors.lastname: Blázquez
authors.forename: Gala
authors.initials: G
authors.lastname: López
authors.forename: Talía
authors.initials: T
authors.lastname: Sainz
authors.forename: M
authors.initials: M
authors.lastname: Muñoz
authors.forename: Tomás
authors.initials: T
authors.lastname: Alonso
authors.forename: Manuel
authors.initials: M
authors.lastname: Moro
mesh_terms: D000328:Adult; D017954:Africa South of the Sahara / Q000208:ethnology; D000907:Antibodies, Bacterial / Q000097:blood*; D000913:Antibodies, Protozoan / Q000097:blood*; D000914:Antibodies, Viral / Q000097:blood*; D001210:Asia, Southeastern / Q000208:ethnology; D003430:Cross-Sectional Studies; D054242:Emigrants and Immigrants; D005061:Europe, Eastern / Q000208:ethnology; D005260:Female; D015483:HIV Antibodies / Q000097:blood; D006510:Hepatitis B Antibodies / Q000097:blood; D018937:Hepatitis C Antibodies / Q000097:blood; D006801:Humans; D018445:Infectious Disease Transmission, Vertical; D007843:Latin America / Q000208:ethnology; D009018:Morocco / Q000208:ethnology; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000097:blood / Q000208:ethnology* / Q000382:microbiology / Q000469:parasitology / Q000821:virology; D012189:Retrospective Studies; D012412:Rubella virus / Q000276:immunology; D013030:Spain / Q000453:epidemiology; D014122:Toxoplasma / Q000276:immunology; D014210:Treponema pallidum / Q000276:immunology; D014349:Trypanosoma cruzi / Q000276:immunology
chemical_list: D000907:Antibodies, Bacterial; D000913:Antibodies, Protozoan; D000914:Antibodies, Viral; D015483:HIV Antibodies; D006510:Hepatitis B Antibodies; D018937:Hepatitis C Antibodies