title: Small RNA RyhB as a potential tool used for metabolic engineering in Escherichia coli.
abstract: Small RNA (RyhB) was overexpressed artificially using an arabinose-inducible system in Escherichia coli and resulted in more succinate (7-fold) accumulation, which suggested that RyhB had a strong effect on sdhCDAB genes. Acetate was also increased indicating that RyhB had a comprehensive influence on glucose central metabolism. RyhB might therefore be useful for metabolic engineering of E. coli.
authors.affiliation: State Key Laboratory of Microbial Technology, Shandong University, Jinan 250100, People's Republic of China.
authors.forename: Zhen
authors.initials: Z
authors.lastname: Kang
authors.forename: Xinran
authors.initials: X
authors.lastname: Wang
authors.forename: Yikui
authors.initials: Y
authors.lastname: Li
authors.forename: Qian
authors.initials: Q
authors.lastname: Wang
authors.forename: Qingsheng
authors.initials: Q
authors.lastname: Qi
mesh_terms: D000085:Acetates / Q000378:metabolism; D004926:Escherichia coli / Q000235:genetics*; D015870:Gene Expression; D015964:Gene Expression Regulation, Bacterial; D005947:Glucose / Q000378:metabolism; D060847:Metabolic Engineering / Q000379:methods*; D058727:RNA, Small Untranslated / Q000235:genetics* / Q000378:metabolism; D019802:Succinic Acid / Q000378:metabolism
chemical_list: D000085:Acetates; D058727:RNA, Small Untranslated; D019802:Succinic Acid; D005947:Glucose