title: The importance of PK/PD data-key biological answers needed to evaluate the success of potential cancer therapeutics.
authors.affiliation: GlaxoSmithKline Research & Development Oncology R&D, Collegeville, PA 19426, USA. rakesh.2.kumar@gsk.com
authors.forename: Rakesh
authors.initials: R
authors.lastname: Kumar
authors.forename: Benjamin
authors.initials: B
authors.lastname: Suttle
mesh_terms: D000970:Antineoplastic Agents / Q000493:pharmacokinetics*; D005770:Gastrointestinal Neoplasms / Q000235:genetics*; D005819:Genetic Markers; D010879:Piperazines / Q000493:pharmacokinetics* / Q000494:pharmacology*; D011743:Pyrimidines / Q000493:pharmacokinetics* / Q000494:pharmacology*
chemical_list: D000970:Antineoplastic Agents; D005819:Genetic Markers; D010879:Piperazines; D011743:Pyrimidines