title: [Cost analysis of rapid methods for diagnosis of multidrug resistant tuberculosis in different epidemiologic groups in Perú].
abstract: OBJECTIVE
  To evaluate the costs of three methods for the diagnosis of drug susceptibility in tuberculosis, and to compare the cost per case of Multidrug-resistant tuberculosis (MDR TB) diagnosed with these (MODS, GRIESS and Genotype MTBDR plus®) in 4 epidemiologic groups in Peru.
  
  
  METHODS
  In the basis of programmatic figures, we divided the population in 4 groups: new cases from Lima/Callao, new cases from other provinces, previously treated patients from Lima/Callao and previously treated from other provinces. We calculated the costs of each test with the standard methodology of the Ministry of Health, from the perspective of the health system. Finally, we calculated the cost per patient diagnosed with MDR TB for each epidemiologic group.
  
  
  RESULTS
  The estimated costs per test for MODS, GRIESS, and Genotype MTBDR plus® were 14.83. 15.51 and 176.41 nuevos soles respectively (the local currency, 1 nuevos sol=0.36 US dollars for August, 2011). The cost per patient diagnosed with GRIESS and MODS was lower than 200 nuevos soles in 3 out of the 4 groups. The costs per diagnosed MDR TB were higher than 2,000 nuevos soles with Genotype MTBDR plus® in the two groups of new patients, and lower than 1,000 nuevos soles in the group of previously treated patients.
  
  
  CONCLUSIONS
  In high-prevalence groups, like the previously treated patients, the costs per diagnosis of MDR TB with the 3 evaluated tests were low, nevertheless, the costs with the molecular test in the low- prevalence groups were high. The use of the molecular tests must be optimized in high prevalence areas.
authors.affiliation: Instituto Nacional de Salud del Perú, Lima, Perú. lelysol@hotmail.com
authors.forename: Lely
authors.initials: L
authors.lastname: Solari
authors.forename: Alfonso
authors.initials: A
authors.lastname: Gutiérrez
authors.forename: Carmen
authors.initials: C
authors.lastname: Suárez
authors.forename: Oswaldo
authors.initials: O
authors.lastname: Jave
authors.forename: Edith
authors.initials: E
authors.lastname: Castillo
authors.forename: Gloria
authors.initials: G
authors.lastname: Yale
authors.forename: Luis
authors.initials: L
authors.lastname: Ascencios
authors.forename: Neyda
authors.initials: N
authors.lastname: Quispe
authors.forename: Eddy
authors.initials: E
authors.lastname: Valencia
authors.forename: Víctor
authors.initials: V
authors.lastname: Suárez
mesh_terms: D001431:Bacteriological Techniques / Q000191:economics / Q000379:methods; D003365:Costs and Cost Analysis; D006801:Humans; D010568:Peru / Q000453:epidemiology; D013997:Time Factors; D018088:Tuberculosis, Multidrug-Resistant / Q000175:diagnosis* / Q000191:economics* / Q000453:epidemiology