title: A method to enhance spatial resolution of a 2D ion chamber array for quality control of MLC.
abstract: This work introduces a new method for verifying MLC leaf positions with enough spatial resolution to replace film-based methods in performing QA tests. It is implemented on a 2D ion chamber array, and it is based on the principle of varying signal response of a volumetric detector to partial irradiation. A PTW 2D-ARRAY seven29 (PTW-729 2D) array was used to assess a Siemens OPTIFOCUS MLC. Partial volume response curves for chambers in the array were obtained by irradiating them with the leaves of the MLC, progressively covering varying portions of the chambers correlated with the leaf positions. The readings from the array's chambers are processed with an in-house program; it generates a reference response that translates readings into leaf positions. This principle allows discriminating errors in pairs of opposing leaves that could combine to cancel their detection with other tools. Patterns of leaf positions, similar to the Bayouth test but with different, purposefully introduced errors, were generated and used to test the effectiveness of the method. The same patterns were exposed on radiographic film and analyzed with the RIT software for validation. For four test patterns with a total of 100 errors of ± 1 mm, ± 2 mm and ± 3 mm, all were correctly determined with the proposed method. The analysis of the same pattern with film using the Bayouth routine in the RIT software resulted in either somewhat low true positives combined with a large fraction of false positives, or a low true positive rate with a low false positive ratio, the results being significantly affected by the threshold selected for the analysis. This method provides an effective, easy to use tool for quantitative MLC QA assessment, with excellent spatial resolution. It can be easily applied to other 2D arrays, as long as they exhibit a partial volume detector response.
authors.affiliation: Departamento de Neurocirugía, Instituto de Neurología y Neurocirugía, La Habana, Cuba. romoreno@infomed.sld.cu
authors.forename: Rogelio
authors.initials: R
authors.lastname: Diaz Moreno
authors.forename: Daniel
authors.initials: D
authors.lastname: Venencia
authors.forename: Edgardo
authors.initials: E
authors.lastname: Garrigo
authors.forename: Yakov
authors.initials: Y
authors.lastname: Pipman
mesh_terms: D011785:Quality Assurance, Health Care / Q000379:methods; D011879:Radiotherapy Dosage; D020266:Radiotherapy, Conformal / Q000379:methods*; D012680:Sensitivity and Specificity
references.citation: Med Phys. 2003 May;30(5):743-50
references.pmid: 12772980
references.citation: Med Phys. 2007 Oct;34(10):3825-37
references.pmid: 17985628
references.citation: Med Phys. 2006 Apr;33(4):1005-15
references.pmid: 16696477
references.citation: Med Phys. 2009 Jul;36(7):3304-9
references.pmid: 19673226
references.citation: Int J Radiat Oncol Biol Phys. 2008;71(1 Suppl):S93-7
references.pmid: 18406947
references.citation: Phys Med Biol. 2005 Jul 21;50(14):3361-73
references.pmid: 16177515
references.citation: J Appl Clin Med Phys. 2009 Feb 05;10(1):120-128
references.pmid: 19223841
references.citation: Strahlenther Onkol. 2005 Jul;181(7):468-74
references.pmid: 15995841
references.citation: Med Phys. 2003 Mar;30(3):433-41
references.pmid: 12674244