title: Detection of malathion, fenthion and methidathion by using heparin-reduced gold nanoparticles.
abstract: Green-synthesized gold nanoparticles were utilized for the detection of organophosphorous pesticides. Heparin, one of glycosaminoglycans, was used as a reducing and stabilizing agent. The reaction conditions were optimized, and high resolution-transmission electron microscopic images revealed gold nanoparticles of various shapes. Organophosphorous pesticides in water were detected by simply mixing them with gold nanoparticles. NaCl induced a color change in the mixed solution from wine-red to purple-blue that was dependent on the pesticide concentration in the range of 10-1,000 ppb. Gold nanoparticles were immobilized on a silica gel matrix in order to prepare solid supports for removing pesticides. The incorporation of atomic gold and heparin bound to 2 g of silica gel was determined 4,058 ppm and 33 microg as measured by inductively coupled plasma-atomic emission spectrophotometry and carbazole assay, respectively. AuNPs-immobilized silica gel columns were successfully applied for removing fenthion in water confirmed by RP-HPLC and FT-IR analyses.
authors.affiliation: College of Pharmacy, Inje University, 607 Obang-dong, Gimhae, Gyeongnam 621-749, Republic of Korea.
authors.forename: Youmie
authors.initials: Y
authors.lastname: Park
authors.forename: A-Rang
authors.initials: AR
authors.lastname: Im
authors.forename: Yoo Na
authors.initials: YN
authors.lastname: Hong
authors.forename: Chong-Kook
authors.initials: CK
authors.lastname: Kim
authors.forename: Yeong Shik
authors.initials: YS
authors.lastname: Kim
mesh_terms: D002851:Chromatography, High Pressure Liquid; D005284:Fenthion / Q000032:analysis*; D006046:Gold / Q000737:chemistry*; D006493:Heparin / Q000737:chemistry*; D008294:Malathion / Q000032:analysis*; D053768:Metal Nanoparticles; D046529:Microscopy, Electron, Transmission; D009946:Organothiophosphorus Compounds / Q000032:analysis*; D010575:Pesticides / Q000032:analysis* / Q000302:isolation & purification; D014874:Water Pollutants, Chemical / Q000032:analysis* / Q000302:isolation & purification
chemical_list: D009946:Organothiophosphorus Compounds; D010575:Pesticides; D014874:Water Pollutants, Chemical; D006046:Gold; D006493:Heparin; D005284:Fenthion; D008294:Malathion; C005828:methidathion