title: Rhodococcus equi: clinical manifestations, virulence, and immunity.
abstract: Pneumonia is a major cause of disease and death in foals. Rhodococcus equi, a gram-positive facultative intracellular pathogen, is a common cause of pneumonia in foals. This article reviews the clinical manifestations of infection caused by R. equi in foals and summarizes current knowledge regarding mechanisms of virulence of, and immunity to, R. equi. A complementary consensus statement providing recommendations for the diagnosis, treatment, control, and prevention of infections caused by R. equi in foals can be found in the same issue of the Journal.
authors.affiliation: Department of Large Animal Medicine, University of Georgia, Athens, GA 30602, USA. gigueres@uga.edu
authors.forename: S
authors.initials: S
authors.lastname: Giguère
authors.forename: N D
authors.initials: ND
authors.lastname: Cohen
authors.forename: M Keith
authors.initials: MK
authors.lastname: Chaffin
authors.forename: S A
authors.initials: SA
authors.lastname: Hines
authors.forename: M K
authors.initials: MK
authors.lastname: Hondalus
authors.forename: J F
authors.initials: JF
authors.lastname: Prescott
authors.forename: N M
authors.initials: NM
authors.lastname: Slovis
mesh_terms: D000193:Actinomycetales Infections / Q000276:immunology / Q000382:microbiology / Q000662:veterinary*; D000818:Animals; D006734:Horse Diseases / Q000382:microbiology* / Q000473:pathology; D006736:Horses; D016929:Rhodococcus equi / Q000472:pathogenicity* / Q000502:physiology*; D014774:Virulence