title: Magnetic resonance imaging signal hyperintensity of neural tissues in diffuse chronic pain syndromes: a pilot study.
abstract: In this pilot study we use T2-weighted magnetic resonance imaging (MRI) to identify possible peripheral nerve inflammation in 4 patients with diffuse chronic pain. In all 4 patients, there was an increase in median and ulnar nerve T2 signal intensity at the wrist (P < 0.05 vs. controls). Positive clinical signs of peripheral nerve mechanosensitivity combined with MRI findings suggest that these patients may have an underlying peripheral nerve pathology.
authors.affiliation: Brighton and Sussex Medical School, University of Sussex, Falmer, Brighton BN1 9PS, UK. a.dilley@bsms.ac.uk
authors.forename: Andrew
authors.initials: A
authors.lastname: Dilley
authors.forename: Jane
authors.initials: J
authors.lastname: Greening
authors.forename: Karen
authors.initials: K
authors.lastname: Walker-Bone
authors.forename: Catriona
authors.initials: C
authors.lastname: Good
mesh_terms: D000328:Adult; D059350:Chronic Pain / Q000473:pathology*; D005260:Female; D005356:Fibromyalgia / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D009474:Neurons / Q000473:pathology*; D010865:Pilot Projects; D013577:Syndrome; D055815:Young Adult