title: P/S ligands derived from carbohydrates in Rh-catalyzed hydrosilylation of ketones.
abstract: Reported is the synthesis of a number of diastereomerically pure cationic Rh(I)-complexes I starting from phosphinite thioglycosides. These complexes were used in the asymmetric hydrosilylation of prochiral ketones. The reactivity and enantioselectivity of the reaction was shown to be dependent on the pyranose ring, the substituent at the sulfur atom, the hydroxylic protective groups and most significantly on the alkene co-ligand.
authors.affiliation: Instituto de Investigaciones Químicas (IIQ), CSIC-Universidad de Sevilla, c/. Américo Vespucio, 49., Isla de la Cartuja, 41092 Sevilla, Spain. khiar@iiq.csic.es
authors.forename: Noureddine
authors.initials: N
authors.lastname: Khiar
authors.forename: Manuel
authors.initials: M
authors.lastname: Pernía Leal
authors.forename: Raquel
authors.initials: R
authors.lastname: Navas
authors.forename: Juan
authors.initials: J
authors.lastname: Francisco Moya
authors.forename: María Victoria
authors.initials: MV
authors.lastname: García Pérez
authors.forename: Inmaculada
authors.initials: I
authors.lastname: Fernández
mesh_terms: D000438:Alcohols / Q000138:chemical synthesis* / Q000737:chemistry; D007659:Ketones / Q000737:chemistry*; D008024:Ligands; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D012238:Rhodium / Q000737:chemistry*; D013237:Stereoisomerism; D013865:Thioglycosides / Q000737:chemistry*
chemical_list: D000438:Alcohols; D007659:Ketones; D008024:Ligands; D009942:Organometallic Compounds; D013865:Thioglycosides; D012238:Rhodium