title: Photosensitivity induced by naproxen.
abstract: We present two cases of systemic photosensitivity due to naproxen that presented as photodistributed erythema multiforme (EM) and lichenoid photodermatitis (LP). Although naproxen is a commonly used nonsteroidal antinflammatory drug and has the capacity of causing systemic photosensitivity, there are very few reports about it in the literature. The diagnosis was suspected by the recent ingestion of the drug and the photodistribution of the lesions. A positive photopatch test in the first patient and the normalization of the MED-UVB after discontinuing naproxen in the second patient supported the diagnosis.
authors.affiliation: Department of Dermatology, Complejo Hospitalario Universitario, Faculty of Medicine, Santiago de Compostela, Spain. egutgon@hotmail.com
authors.forename: Enrique
authors.initials: E
authors.lastname: Gutiérrez-González
authors.forename: Laura
authors.initials: L
authors.lastname: Rodríguez-Pazos
authors.forename: Maria Teresa
authors.initials: MT
authors.lastname: Rodríguez-Granados
authors.forename: Jaime
authors.initials: J
authors.lastname: Toribio
mesh_terms: D000328:Adult; D000368:Aged; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000009:adverse effects*; D004892:Erythema Multiforme / Q000139:chemically induced* / Q000175:diagnosis* / Q000473:pathology; D005260:Female; D006801:Humans; D009288:Naproxen / Q000008:administration & dosage / Q000009:adverse effects*; D010787:Photosensitivity Disorders / Q000139:chemically induced* / Q000175:diagnosis* / Q000473:pathology
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D009288:Naproxen