title: Density spectral array analysis of SREDA during EEG-video monitoring.
abstract: OBJECTIVE
  To report the temporal pattern of subclinical rhythmic electrographic discharge of adults (SREDA) and its response to lorazepam during EEG-video monitoring.
  
  
  METHODS
  We recorded EEG-video for 3 days in a patient with SREDA, who was previously misdiagnosed with generalized epilepsy. Because SREDA had a very prominent signature on density spectral array (DSA), we used DSA to study the pattern of SREDA over the diurnal cycle, and the response to intravenous lorazepam.
  
  
  RESULTS
  SREDA occurred in both waking and sleep, but tended to occur in single bursts in waking and in longer clusters during sleep. Lorazepam suppressed SREDA.
  
  
  CONCLUSIONS
  The temporal pattern of SREDA varies during the sleep-wake cycle. Lorazepam appears to suppress SREDA.
  
  
  CONCLUSIONS
  Response to lorazepam cannot distinguish SREDA from electrographic seizure activity.
authors.affiliation: Division of Epilepsy, Department of Neurology, Vanderbilt University, Nashville, TN, USA.
authors.forename: Robert P
authors.initials: RP
authors.lastname: Carson
authors.forename: Bassel W
authors.initials: BW
authors.lastname: Abou-Khalil
mesh_terms: D000328:Adult; D001921:Brain / Q000502:physiology* / Q000503:physiopathology; D003951:Diagnostic Errors; D004569:Electroencephalography / Q000379:methods*; D004827:Epilepsy / Q000175:diagnosis* / Q000503:physiopathology; D005260:Female; D006801:Humans