title: Mollenyne A, a long-chain chlorodibromohydrin amide from the sponge Spirastrella mollis.
abstract: The structure of mollenyne A, a cytotoxic nitrogenous halogenated long-chain carboxamide from the sponge Spirastrella mollis, was elucidated by integrated spectroscopic analysis, including CD, and chemical conversion.
authors.affiliation: Department of Chemistry and Biochemistry, University of California San Diego, 9500 Gilman Drive MC0358, La Jolla, California 92093, USA.
authors.forename: Brandon I
authors.initials: BI
authors.lastname: Morinaka
authors.forename: Tadeusz F
authors.initials: TF
authors.lastname: Molinski
mesh_terms: D000577:Amides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D000818:Animals; D000970:Antineoplastic Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D002942:Circular Dichroism; D004354:Drug Screening Assays, Antitumor; D045325:HCT116 Cells; D006801:Humans; D006846:Hydrocarbons, Halogenated / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D008055:Lipids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D011161:Porifera / Q000737:chemistry*
chemical_list: D000577:Amides; D000970:Antineoplastic Agents; D006846:Hydrocarbons, Halogenated; D008055:Lipids; C569911:mollenyne A
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