title: Risk factors and clinical presentation of cats with feline idiopathic cystitis.
abstract: Feline idiopathic cystitis (FIC) is the most common cause of feline lower urinary tract disease (FLUTD). This retrospective, case-controlled study evaluated possible risk factors associated with FIC and compared different clinical presentations in 64 cats with FIC. Several risk factors known to be involved in FLUTD were identified as playing a role in FIC. Of the stressful situations considered, most did not occur with increased frequency in cats with FIC compared to controls, except for a house move. The presence of pyuria, haematuria and an increased urine protein:creatinine ratio were significantly higher in obstructed males compared with non-obstructed males. An obstruction was significantly more likely in cats with struvite crystalluria compared with cats without struvite crystalluria. These findings suggest that urethral plugs might be an important cause or contributing factor of obstruction in FIC. Episodes of FIC seem to occur mainly in susceptible cats in combination with a deficient environment.
authors.affiliation: Department of Small Animal Medicine and Clinical Biology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B-9820 Merelbeke, Belgium. pieter.defauw@ugent.be
authors.forename: Pieter A M
authors.initials: PA
authors.lastname: Defauw
authors.forename: Isabel
authors.initials: I
authors.lastname: Van de Maele
authors.forename: Luc
authors.initials: L
authors.lastname: Duchateau
authors.forename: Ingeborgh E
authors.initials: IE
authors.lastname: Polis
authors.forename: Jimmy H
authors.initials: JH
authors.lastname: Saunders
authors.forename: Sylvie
authors.initials: S
authors.lastname: Daminet
mesh_terms: D000818:Animals; D001530:Belgium / Q000453:epidemiology; D001947:Breeding; D016022:Case-Control Studies; D002371:Cat Diseases / Q000453:epidemiology* / Q000652:urine; D002415:Cats; D003556:Cystitis / Q000453:epidemiology / Q000662:veterinary*; D005260:Female; D017616:Magnesium Compounds / Q000652:urine; D008297:Male; D010710:Phosphates / Q000652:urine; D012189:Retrospective Studies; D012307:Risk Factors; D000069877:Struvite
chemical_list: D017616:Magnesium Compounds; D010710:Phosphates; D000069877:Struvite
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