title: The importance of HT-ADME in drug discovery.
abstract: The inaugural meeting of the Boston Society High-Throughput Absorption, Distribution, Metabolism and Excretion (HT-ADME) Conference was held in Cambridge, MA (USA). The theme was 'The Importance of HT-ADME in Drug Discovery' and the organizers of the conference stressed the importance of incorporating audience participation and discussion in the field. The conference hosted 65 attendees and 16 presentations, which was a good size to achieve the goal of active participation while maintaining focus on HT-ADME. The speakers provided broad coverage of HT-ADME within the drug discovery arena, while remembering that the overall goal in drug discovery is identifying potential drug candidates to move forward into development.
authors.affiliation: Bioanalytical Research Group, Bristol-Myers Squibb, Wallingford, CT 06492, USA. daniel.morgan@bms.com
authors.forename: Daniel
authors.initials: D
authors.lastname: Morgan
mesh_terms: D002626:Chemistry, Pharmaceutical; D003198:Computer Simulation; D055808:Drug Discovery / Q000379:methods*; D004353:Drug Evaluation, Preclinical / Q000379:methods; D057166:High-Throughput Screening Assays; D008657:Metabolic Clearance Rate; D008954:Models, Biological; D004364:Pharmaceutical Preparations / Q000737:chemistry / Q000378:metabolism; D010599:Pharmacokinetics; D012984:Software; D014018:Tissue Distribution
chemical_list: D004364:Pharmaceutical Preparations