title: Comparison of higher order aberrations after implantable Collamer Lens implantation and wavefront-guided LASEK in high myopia.
abstract: OBJECTIVE
  To compare changes in ocular higher order aberrations (HOAs) after Visian Implantable Collamer Lens (ICL, STAAR Surgical Co) implantation and wavefront-guided laser epithelial keratomileusis (WFG-LASEK) to correct high myopia.
  
  
  METHODS
  This prospective case series comprised 30 eyes (18 patients) that underwent ICL implantation (ICL group) and 33 eyes (18 patients) that underwent WFG-LASEK (WFG-LASEK group). All eyes had spherical equivalent of -6.00 to -9.00 diopters. Entire ocular, internal optic, and corneal HOAs were measured before surgery and 3 months after surgery using a laser ray tracing aberrometer. Contrast sensitivity testing was performed in 10 eyes from each group at a photopic light level of 85 cd/m(2) and a mesopic level of 3 cd/m(2) 3 months after surgery.
  
  
  RESULTS
  In the ICL group, HOAs changed for the entire ocular trefoil-y, spherical aberration, internal optic spherical aberration, and corneal trefoil-y. In the WFG-LASEK group, increased HOAs were observed for total HOAs, entire ocular and corneal spherical aberration, secondary astigmatism, and tetrafoil. The ICL group had lower induced aberration values of entire ocular and corneal HOAs compared with the WFG-LASEK group. No significant differences in contrast sensitivity values between groups at the photopic level were noted; however, contrast sensitivity values were significantly lower for 3 (P=.01) and 6 cycles per degree (P<.001) in the WFG-LASEK group at the mesopic level. At the mesopic level, total HOAs, trefoil-y, spherical aberration, and secondary astigmatism were higher in the WFG-LASEK group.
  
  
  CONCLUSIONS
  Implantable Collamer Lens implantation induced fewer ocular and corneal HOAs and resulted in better contrast sensitivity at mesopic levels than WFG-LASEK in eyes with high myopia.
authors.affiliation: Institute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: Joo Youn
authors.initials: JY
authors.lastname: Shin
authors.forename: Hyunseok
authors.initials: H
authors.lastname: Ahn
authors.forename: Kyoung Yul
authors.initials: KY
authors.lastname: Seo
authors.forename: Eung Kweon
authors.initials: EK
authors.lastname: Kim
authors.forename: Tae-Im
authors.initials: TI
authors.lastname: Kim
mesh_terms: D057128:Aberrometry; D000328:Adult; D000867:Anterior Chamber / Q000601:surgery; D015350:Contrast Sensitivity / Q000502:physiology; D057108:Corneal Wavefront Aberration / Q000503:physiopathology*; D005260:Female; D006801:Humans; D049008:Keratectomy, Subepithelial, Laser-Assisted; D054018:Lasers, Excimer / Q000627:therapeutic use*; D019654:Lens Implantation, Intraocular; D008297:Male; D047728:Myopia, Degenerative / Q000503:physiopathology / Q000601:surgery*; D054120:Phakic Intraocular Lenses; D011446:Prospective Studies; D014792:Visual Acuity / Q000502:physiology; D055815:Young Adult