title: Concomitant infection and local metal reaction in patients undergoing revision of metal on metal total hip arthroplasty.
abstract: Total hip arthroplasty (THA) with conventional polyethylene bearings is traditionally the standard operative treatment for endstage arthritis of the hip. This design has excellent survivorship in most populations, with a low occurrence of infection and other associated complications. Due to concern over increased wear in younger, more active populations, other bearing surfaces have been evaluated, particularly metal-on-metal with wear rates theorized to be lower than conventional THA. Unique to metal-on-metal THA, however, is the possibility of local soft tissue reactions that can mimic infection, making proper diagnosis and treatment difficult. We present a case series of nine hips in eight patients undergoing revision of metal-on-metal THA for local soft tissue reactions, three of which were also found to be concomitantly infected. The laboratory and hip aspirate data described show significant overlap between the infected and non-infected cases. Care must be taken when evaluating patients with failed metal-on-metal THA as there may be an increased incidence of co-infection in this group of patients.
authors.affiliation: Department of Orthopaedics and Rehabilitation, The University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Iowa City, IA 52242, USA.
authors.forename: Kyle T
authors.initials: KT
authors.lastname: Judd
authors.forename: Nicolas
authors.initials: N
authors.lastname: Noiseux
mesh_terms: D000368:Aged; D019644:Arthroplasty, Replacement, Hip / Q000009:adverse effects*; D003646:Debridement; D005260:Female; D005549:Foreign-Body Reaction / Q000150:complications* / Q000175:diagnosis; D006622:Hip Prosthesis / Q000009:adverse effects*; D006801:Humans; D007593:Joint Instability / Q000209:etiology / Q000382:microbiology / Q000601:surgery; D008297:Male; D008670:Metals / Q000009:adverse effects*; D008875:Middle Aged; D011475:Prosthesis Failure / Q000009:adverse effects; D016459:Prosthesis-Related Infections / Q000150:complications* / Q000175:diagnosis / Q000601:surgery*; D012086:Reoperation; D012189:Retrospective Studies; D013290:Streptococcal Infections / Q000150:complications / Q000175:diagnosis; D007507:Therapeutic Irrigation
chemical_list: D008670:Metals
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