title: Thiacalix[4]arene based fluorescent probe for sensing and imaging of Fe3+ ions.
abstract: A thiacalix[4]arene based fluorescent chemosensor 3 in the cone conformation has been synthesized and its recognition behaviour is evaluated toward various metal ions in mixed aqueous media. The chemosensor 3 showed high selectivity towards Fe(3+) ions by fluorescence quenching of excimer emission. Further, evaluation of the 3·Fe(3+) complex prepared in situ demonstrated great promise for the detection of the Fe(3+) ion in the presence of amino acids, blood serum and bovine serum albumin (BSA) solution. The compound 3 has suitable permeability into the PC3 cells and can be utilized as a Fe(3+) selective sensor in living cells (PC3 cells).
authors.affiliation: Department of Chemistry, UGC-Center for Advance Studies-1, Guru Nanak Dev University, Amritsar, Punjab, India. mksharmaa@yahoo.co.in
authors.forename: Manoj
authors.initials: M
authors.lastname: Kumar
authors.forename: Rajesh
authors.initials: R
authors.lastname: Kumar
authors.forename: Vandana
authors.initials: V
authors.lastname: Bhalla
authors.forename: Parduman Raj
authors.initials: PR
authors.lastname: Sharma
authors.forename: Tandeep
authors.initials: T
authors.lastname: Kaur
authors.forename: Yasrib
authors.initials: Y
authors.lastname: Qurishi
mesh_terms: D000818:Animals; D002412:Cations; D002417:Cattle; D045744:Cell Line, Tumor; D005290:Ferric Compounds / Q000032:analysis* / Q000097:blood; D005456:Fluorescent Dyes / Q000138:chemical synthesis* / Q000737:chemistry; D006801:Humans; D015394:Molecular Structure; D010636:Phenols / Q000737:chemistry*; D012710:Serum Albumin, Bovine / Q000737:chemistry; D013050:Spectrometry, Fluorescence; D013440:Sulfides / Q000737:chemistry*
chemical_list: D002412:Cations; D005290:Ferric Compounds; D005456:Fluorescent Dyes; D010636:Phenols; D013440:Sulfides; C500450:thiacalix(4)arene; D012710:Serum Albumin, Bovine