title: Intestinal adenocarcinoma arising in urinary conduits.
abstract: It is estimated that >10,000 patients who undergo cystectomy for bladder             cancer in the US each year receive a conventional ileal conduit and that >2,000             receive a continent urinary diversion. Case reports of primary intestinal adenocarcinomas             in urinary conduits have been published recently, mainly in the urology literature.             An epidemic of such cancers in this small, high-risk population seems to be emerging,             particularly in conduits that utilize the colon. A case report and literature             review was carried out. We describe a patient with a new primary adenocarcinoma             arising in a colonic neobladder. We summarize prior literature describing intestinal             adenocarcinomas that developed in an intestinal segment used for urinary diversion.             Patients with urinary conduits of all types (particularly those utilizing colon             rather than ileum) are at high risk of developing a second primary intestinal             adenocarcinoma in the conduit. This population is likely to benefit from surveillance             measures aimed at detecting such cancers. The primary form of therapy remains             adequate surgical resection. General surgeons should be aware of such patients             as they may be involved in the diagnosis of, and surgery for, the cancer in the             conduit.
authors.affiliation: Department of Surgery, Saint Louis University Medical Center, Saint Louis University Hospital, St. Louis, MO 63110, USA.
authors.forename: Genevieve C
authors.initials: GC
authors.lastname: Moyer
authors.forename: Robert L
authors.initials: RL
authors.lastname: Grubb
authors.forename: Frank E
authors.initials: FE
authors.lastname: Johnson
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology*; D002295:Carcinoma, Transitional Cell / Q000601:surgery*; D006801:Humans; D007414:Intestinal Neoplasms / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D016609:Neoplasms, Second Primary / Q000473:pathology*; D001749:Urinary Bladder Neoplasms / Q000601:surgery*; D014547:Urinary Diversion