title: Cell-cell junctions: α-catenin and E-cadherin help fence in Yap1.
abstract: Metazoan cells translate adhesive events with neighbors into anti-proliferative signals in the nucleus. The cadherin-catenin adhesion complex has long been suspected of playing a key role in this process, and three recent papers suggest that it does so by modulating subcellular localization of the Hippo pathway component Yap1.
authors.affiliation: Department of Cell Biology, Emory University School of Medicine, Atlanta, GA 30322, USA.
authors.forename: Brian S
authors.initials: BS
authors.lastname: Robinson
authors.forename: Kenneth H
authors.initials: KH
authors.lastname: Moberg
mesh_terms: D048868:Adaptor Proteins, Signal Transducing / Q000235:genetics / Q000378:metabolism*; D000818:Animals; D015820:Cadherins / Q000235:genetics / Q000378:metabolism*; D002460:Cell Line; D002467:Cell Nucleus / Q000235:genetics / Q000378:metabolism*; D049109:Cell Proliferation; D003260:Contact Inhibition; D006801:Humans; D051379:Mice; D015398:Signal Transduction; D051178:alpha Catenin / Q000235:genetics / Q000378:metabolism*
chemical_list: D048868:Adaptor Proteins, Signal Transducing; D015820:Cadherins; D051178:alpha Catenin
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