title: [A review of toxicity superselective intra-arterial concurrent chemoradiotherapy(SIACC)for oral cancer].
abstract: Superselective intra-arterial concurrent chemoradiotherapy(SIACC)for oral cancer has been favored for its efficacy and ability to not damage organs. SIACC was applied to 13 previously untreated patients with oral cancer for the purpose of avoiding surgical resection of the primary tumor in our hospital from 2007 to 2009. Although a complete response of the primary tumor was achieved in all cases, various adverse events also occurred. All patients experienced leucopenia, and most patients suffered from mucotitis and dry mouth. One patient had dizziness and nausea due to the catheter insertion into the vertebra artery. Although SIACC is an important treatment strategy for oral cancer, careful attention for adverse events should be taken into account during and after treatment.
authors.affiliation: Dept. of Regenerative Oral Surgery Unit of Translational Medicine, Nagasaki University, Japan.
authors.forename: Takeshi
authors.initials: T
authors.lastname: Shiraishi
authors.forename: Masataka
authors.initials: M
authors.lastname: Uehara
authors.forename: Mihoko
authors.initials: M
authors.lastname: Ikeda
authors.forename: Nobutaka
authors.initials: N
authors.lastname: Tajima
authors.forename: Hideyoshi
authors.initials: H
authors.lastname: Ikeda
authors.forename: Takako
authors.initials: T
authors.lastname: Kawasaki
authors.forename: Izumi
authors.initials: I
authors.lastname: Asahina
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D059248:Chemoradiotherapy / Q000009:adverse effects*; D002945:Cisplatin / Q000009:adverse effects* / Q000627:therapeutic use; D000077143:Docetaxel; D005260:Female; D006801:Humans; D007261:Infusions, Intra-Arterial; D007970:Leukopenia / Q000139:chemically induced; D008297:Male; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000628:therapy*; D043823:Taxoids / Q000009:adverse effects* / Q000627:therapeutic use
chemical_list: D043823:Taxoids; D000077143:Docetaxel; D002945:Cisplatin