title: Bilateral, symmetrical and extensive cerebral calcification in pseudohypoparathyroidism.
abstract: Pseudohypoparathyroidism (PHP) is a heterogeneous group of disorders characterized by hypocalcemia, hyperphosphatemia, increased serum concentration of parathyroid hormone (PTH), and insensitivity to the biological activity of PTH. Pseudohypoparathyroidism is rare sporadic or autosomal dominant disorder having several subtypes (type Ia, Ib, Ic, type II). We report a case who was 27 years old married lady having two children presented in the summer season 2009. Her trousseau's sign was positive, serum calcium 5.5 mg/dl, PTH 137 pgm/ml and CT scan of brain shows bilateral and symmetrical calcification.  She had occasional doubtful seizure and headache for 7 years. Initially clinicians could not reach the diagnosis due to inadequate investigations.
authors.affiliation: Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh.
authors.forename: M N
authors.initials: MN
authors.lastname: Islam
authors.forename: M A
authors.initials: MA
authors.lastname: Hoque
authors.forename: S A
authors.initials: SA
authors.lastname: Kader
mesh_terms: D000328:Adult; D001927:Brain Diseases / Q000209:etiology*; D002114:Calcinosis / Q000209:etiology*; D002118:Calcium / Q000097:blood; D005260:Female; D006801:Humans; D006996:Hypocalcemia / Q000209:etiology; D010281:Parathyroid Hormone / Q000097:blood; D011547:Pseudohypoparathyroidism / Q000150:complications*
chemical_list: D010281:Parathyroid Hormone; D002118:Calcium