title: Recent progress in Bacillus subtilis sporulation.
abstract: The Gram-positive bacterium Bacillus subtilis can initiate the process of sporulation under conditions of nutrient limitation. Here, we review some of the last 5 years of work in this area, with a particular focus on the decision to initiate sporulation, DNA translocation, cell-cell communication, protein localization and spore morphogenesis. The progress we describe has implications not only just for the study of sporulation but also for other biological systems where homologs of sporulation-specific proteins are involved in vegetative growth.
authors.affiliation: Department of Microbiology and Immunology, College of Physicians and Surgeons, Columbia University, New York, NY, USA.
authors.forename: Douglas
authors.initials: D
authors.lastname: Higgins
authors.forename: Jonathan
authors.initials: J
authors.lastname: Dworkin
mesh_terms: D001412:Bacillus subtilis / Q000166:cytology / Q000254:growth & development* / Q000378:metabolism; D015964:Gene Expression Regulation, Bacterial; D008954:Models, Biological; D021381:Protein Transport; D015398:Signal Transduction; D013171:Spores, Bacterial / Q000166:cytology / Q000254:growth & development* / Q000378:metabolism; D013312:Stress, Physiological
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