title: Light-regulated gene expression in yeast.
abstract: An important basic requirement of synthetic genetic networks is the option of external control of gene expression. Although several chemically inducible systems are available, all of these suffer from the common problem: the chemical inducers are difficult to remove so that to terminate the response. We have described a regulatory expression system for yeast, which employs light as inducer. This light switch translates light-controlled protein-protein interactions into the transcription of selected genes in a dose-dependent and reversible manner.
authors.affiliation: Institute of Plant Biology, Biological Research Centre, Szeged, Hungary.
authors.forename: Laszlo
authors.initials: L
authors.lastname: Kozma-Bognar
authors.forename: Anita
authors.initials: A
authors.lastname: Hajdu
authors.forename: Ferenc
authors.initials: F
authors.lastname: Nagy
mesh_terms: D029681:Arabidopsis Proteins / Q000235:genetics; D005686:Galactokinase / Q000235:genetics; D015870:Gene Expression / Q000528:radiation effects; D008027:Light; D010834:Phytochrome / Q000235:genetics; D011401:Promoter Regions, Genetic / Q000235:genetics; D011993:Recombinant Fusion Proteins / Q000235:genetics; D012441:Saccharomyces cerevisiae / Q000166:cytology / Q000235:genetics* / Q000528:radiation effects*; D029701:Saccharomyces cerevisiae Proteins / Q000235:genetics; D014158:Transcription, Genetic / Q000528:radiation effects; D014170:Transformation, Genetic / Q000528:radiation effects
chemical_list: D029681:Arabidopsis Proteins; C441269:FHY1 protein, Arabidopsis; D011993:Recombinant Fusion Proteins; D029701:Saccharomyces cerevisiae Proteins; D010834:Phytochrome; C524219:GAL1 protein, S cerevisiae; D005686:Galactokinase