title: Appropriate allergy testing and interpretation.
abstract: In vitro tests for specific IgE allow primary care providers to do allergy testing, which can be helpful for allergic patients. Diagnostic testing for allergies is used to determine whether symptoms are caused by IgE antibodies and exposure to an allergen. The presence of IgE in the absence of symptoms does not indicate clinical allergy. Nonselective use of large panels of allergens can lead to false positives and misinterpretation of the results, particularly in food allergy.
authors.affiliation: University of Missouri-Kansas City School of Medicine, USA. jportnoy@cmh.edu
authors.forename: Jay M
authors.initials: JM
authors.lastname: Portnoy
mesh_terms: D000485:Allergens; D006801:Humans; D006967:Hypersensitivity / Q000175:diagnosis* / Q000276:immunology / Q000628:therapy*; D012621:Seasons; D012680:Sensitivity and Specificity; D012882:Skin Tests
chemical_list: D000485:Allergens
references.citation: Ann Allergy Asthma Immunol. 2007 Jul;99(1):34-41
references.pmid: 17650827
references.citation: Ann Allergy. 1993 Sep;71(3):227-9
references.pmid: 8372994
references.citation: J Allergy Clin Immunol. 2004 May;113(5):832-6
references.pmid: 15131563
references.citation: J Allergy Clin Immunol. 1996 Jun;97(6):1193-201
references.pmid: 8648012
references.citation: J Allergy Clin Immunol. 2008 Jul;122(1):145-51
references.pmid: 18502490
references.citation: Ann Allergy Asthma Immunol. 2001 Feb;86(2):196-202
references.pmid: 11258690
references.citation: J Allergy Clin Immunol. 2007 Jun;119(6):1454-61
references.pmid: 17481716
references.citation: Immunol Allergy Clin North Am. 2003 Aug;23(3):389-410, vi
references.pmid: 14524382
references.citation: Clin Exp Allergy. 2005 Sep;35(9):1220-6
references.pmid: 16164451
references.citation: Ann Allergy Asthma Immunol. 2002 Oct;89(4):368-71
references.pmid: 12392380
references.citation: Immunol Allergy Clin North Am. 2003 Aug;23(3):533-47, viii-ix
references.pmid: 14524390
references.citation: Curr Allergy Asthma Rep. 2006 Nov;6(6):455-61
references.pmid: 17026871
references.citation: J Allergy Clin Immunol. 2010 Jul;126(1):33-8
references.pmid: 20451984
references.citation: Ann Allergy Asthma Immunol. 2008 Mar;100(3 Suppl 3):S1-148
references.pmid: 18431959
references.citation: Clin Exp Allergy. 2000 Nov;30(11):1540-6
references.pmid: 11069561
references.citation: Ann Allergy Asthma Immunol. 2006 Jan;96(1):19-23
references.pmid: 16440527
references.citation: J Allergy Clin Immunol. 2001 May;107(5):891-6
references.pmid: 11344358
references.citation: J Allergy Clin Immunol. 2008 Oct;122(4):748-753
references.pmid: 19014766
references.citation: Ann Intern Med. 2004 Feb 17;140(4):278-89
references.pmid: 14970151