title: [Flow Index Vascularization dynamics in the preovulatory phase of controlled ovarian hyperstimulation: profile and relationship with conception rate].
abstract: OBJECTIVE
  To study the evolution of subendometrial vascularization flow index (VFI) in controlled ovarian hyperstimulation (COH+IIU) cycles and compare its dynamic changes in pregnant and non pregnant women.
  
  
  METHODS
  This is a retrospective study on 61 couples. To determine the profile of IVF just before ovulation, patients had 3D-Power Doppler angiography (3D-PDA) in this precise preovulatory phase.
  
  
  RESULTS
  We observed a decreasing profile of VFI in 52% (32/61) of the main group cycles, in 45% (14/31) of the subgroup with spontaneous peak of LH (luteinizing hormone), and in 60% (18/30) of the hCG (human chorionic gonadotropin) trigger subgroup. There were ten conceptions, (10/61, 16.4%), including eight (8/32, 30%) that were associated with a decreasing profile of VFI versus two (2/29, 7%) that were associated with an increasing profile (NS). In the detection of LH peak subgroup, we observed five conceptions (5/14, 36%) associated with a decreasing profile versus one conception (1/17, 6%) associated with an increasing profile of VFI (OR: 8.3; confidence interval [CI] 95%: 0.8-444; P=0.06 in favor of a of decreasing VFI profile). In the hCG subgroup, there were three conceptions in the decreasing VFI profile (3/18, 17%) and one conception with increasing VFI (1/12, 17%, P=0.6).
  
  
  CONCLUSIONS
  In controlled ovarian hyperstimulation, a decreasing VFI profile is more common compared to an increasing one. Such au profile seems to be associated with a higher conception rate in cycles with spontaneous LH surge.
authors.affiliation: Laboratoire d’Eylau, 55, rue Saint-Didier, 75116 Paris, France. philippe@vignal.org
authors.forename: P
authors.initials: P
authors.lastname: Vignal
authors.forename: P
authors.initials: P
authors.lastname: Cohen-Bacrie
authors.forename: E
authors.initials: E
authors.lastname: Sedbon
mesh_terms: D000328:Adult; D000792:Angiography; D006063:Chorionic Gonadotropin / Q000008:administration & dosage; D004717:Endometrium / Q000098:blood supply* / Q000000981:diagnostic imaging; D005260:Female; D005306:Fertilization / Q000502:physiology*; D006801:Humans; D007986:Luteinizing Hormone / Q000097:blood; D008875:Middle Aged; D010062:Ovulation Induction; D011247:Pregnancy; D012189:Retrospective Studies; D018608:Ultrasonography, Doppler
chemical_list: D006063:Chorionic Gonadotropin; D007986:Luteinizing Hormone