title: Efficacy of endoscopic ultrasonography for prediction of tumor depth in gastric cancer.
abstract: OBJECTIVE
  As the proportion of early gastric cancer (EGC) has recently been increased, minimally invasive treatment is currently accepted as main therapy for EGC. Accurate preoperative staging is very important in determining treatment options. To know the accuracy of endoscopic ultrasonography (EUS), we compared the depth of invasion of the tumor with preoperative EUS and postoperative pathologic findings.
  
  
  METHODS
  We retrospectively analyzed 152 patients who underwent EUS before laparoscopic gastrectomy. The preoperative EUS results were compared with the pathological findings.
  
  
  RESULTS
  The overall proportion of coincidence for depth of invasion between EUS and pathologic results was 41.4%. Univariate analysis showed that the rate of corrected prediction of EUS for tumor depth significantly decreased for the lesions more than 3cm in diameter (P=0.033), and those with a depressed morphology (P=0.035). In multivariate analysis, the depressed type (P=0.029, OR=2.873) and upper lesion (P=0.035, OR=2.151) was the significantly independent factors influencing the inaccurate prediction of EUS for tumor depth.
  
  
  CONCLUSIONS
  When we decide the treatment modality considering the clinical depth of invasion by EUS, the possibility of discordance with pathologic results should be considered for the lesions located in the upper third of the stomach and with a depressed morphology.
authors.affiliation: Department of Surgery, Ajou University, School of Medicine, Suwon, Korea.
authors.forename: Ji Min
authors.initials: JM
authors.lastname: Park
authors.forename: Chang Wook
authors.initials: CW
authors.lastname: Ahn
authors.forename: Xian
authors.initials: X
authors.lastname: Yi
authors.forename: Hoon
authors.initials: H
authors.lastname: Hur
authors.forename: Kee Myung
authors.initials: KM
authors.lastname: Lee
authors.forename: Yong Kwan
authors.initials: YK
authors.lastname: Cho
authors.forename: Sang-Uk
authors.initials: SU
authors.lastname: Han
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