title: Renal scarring and osteopontin gene C/T polymorphism in children with primary vesicoureteral reflux.
abstract: We examined for osteopontin (OPN) gene C/T polymorphism in 78 patients (53 girls) with vesicoureteric reflux, with or without renal scarring.  The T allele frequency was associated with a significantly increased risk (26.4 fold) of renal scarring.
authors.affiliation: Department of Pediatric Nephrology, Dortcelik Children Hospital, Bursa, Turkey. drerdoganha@yahoo.com
authors.forename: Hakan
authors.initials: H
authors.lastname: Erdogan
authors.forename: Sevgi
authors.initials: S
authors.lastname: Mir
authors.forename: Afig
authors.initials: A
authors.lastname: Berdeli
authors.forename: Nejat
authors.initials: N
authors.lastname: Aksu
mesh_terms: D000293:Adolescent; D000704:Analysis of Variance; D002648:Child; D002675:Child, Preschool; D002921:Cicatrix / Q000453:epidemiology / Q000235:genetics* / Q000473:pathology; D005260:Female; D020022:Genetic Predisposition to Disease; D006801:Humans; D007223:Infant; D007674:Kidney Diseases / Q000453:epidemiology / Q000235:genetics / Q000473:pathology; D008297:Male; D053495:Osteopontin / Q000235:genetics*; D011110:Polymorphism, Genetic; D014718:Vesico-Ureteral Reflux / Q000453:epidemiology / Q000235:genetics* / Q000473:pathology
chemical_list: D053495:Osteopontin