title: Telomerase activity in the bats Hipposideros armiger and Rousettus leschenaultia.
abstract: Telomerase activity was examined in two species of bat, Hipposideros armiger and Rousettus leschenaultia, which have similar body mass and lifespan but differ in use of hibernation. We found that telomerase activity was present in all tissues sampled, but it was greater in metabolically active tissues such as liver, spleen, and kidney. Of special interest is the raised activity found in the heterothermic bat H. armiger, and the hibernating bats having raised values for spleen, heart, and kidney. These findings show that maintenance of high levels of telomerase is an essential part of the regulation of cellular activities during hibernation.
authors.affiliation: School of Life Sciences, East China Normal University, Shanghai.
authors.forename: Lei
authors.initials: L
authors.lastname: Wang
authors.forename: B M
authors.initials: BM
authors.lastname: McAllan
authors.forename: Guimei
authors.initials: G
authors.lastname: He
mesh_terms: D000818:Animals; D002685:Chiroptera / Q000235:genetics / Q000378:metabolism*; D006605:Hibernation; D007668:Kidney / Q000201:enzymology; D008099:Liver / Q000201:enzymology; D008168:Lung / Q000201:enzymology; D013154:Spleen / Q000201:enzymology; D019098:Telomerase / Q000235:genetics / Q000378:metabolism*
chemical_list: D019098:Telomerase