title: Magneto-optical contrast in liquid-state optically detected NMR spectroscopy.
abstract: We use optical Faraday rotation (OFR) to probe nuclear spins in real time at high-magnetic field in a range of diamagnetic sample fluids. Comparison of OFR-detected NMR spectra reveals a correlation between the relative signal amplitude and the fluid Verdet constant, which we interpret as a manifestation of the variable detuning between the probe beam and the sample optical transitions. The analysis of chemical-shift-resolved, optically detected spectra allows us to set constraints on the relative amplitudes of hyperfine coupling constants, both for protons at chemically distinct sites and other lower-gyromagnetic-ratio nuclei including carbon, fluorine, and phosphorous. By considering a model binary mixture we observe a complex dependence of the optical response on the relative concentration, suggesting that the present approach is sensitive to the solvent-solute dynamics in ways complementary to those known in inductive NMR. Extension of these experiments may find application in solvent suppression protocols, sensitivity-enhanced NMR of metalloproteins in solution, the investigation of solvent-solute interactions, or the characterization of molecular orbitals in diamagnetic systems.
authors.affiliation: Department of Physics, City College of New York, City University of New York, 160 Convent Avenue, New York, NY 10031, USA.
authors.forename: Daniela
authors.initials: D
authors.lastname: Pagliero
authors.forename: Carlos A
authors.initials: CA
authors.lastname: Meriles
mesh_terms: D000465:Algorithms; D001969:Bromobenzenes / Q000737:chemistry; D002244:Carbon / Q000737:chemistry; D055598:Chemical Phenomena; D005461:Fluorine / Q000737:chemistry; D060526:Magnetic Fields; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D008667:Metalloproteins / Q000737:chemistry; D000432:Methanol / Q000737:chemistry; D008956:Models, Chemical; D009904:Optical Rotation; D010758:Phosphorus / Q000737:chemistry; D011522:Protons; D012996:Solutions / Q000737:chemistry*; D012997:Solvents / Q000737:chemistry
chemical_list: D001969:Bromobenzenes; D008667:Metalloproteins; D011522:Protons; D012996:Solutions; D012997:Solvents; D010758:Phosphorus; D005461:Fluorine; D002244:Carbon; C032036:bromobenzene; D000432:Methanol
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