title: Divide and rule: cytodiagnosis of thyroid lesions using pattern analysis: a study of 233 cases.
abstract: Fine needle aspiration cytology (FNAC) of the thyroid is a simple, accurate, fast, economical and safe method for the diagnosis of thyroid lesions on FNA. The objective of this study was application of pattern analysis in the interpretation of thyroid lesions. Two hundred and thirty three cases of thyroid lesion were reviewed, which had histopathological correlation. Smears were classified based on primary (predominant) and secondary (next dominant) pattern and categorized. The variation between combined and final cytological diagnosis was correlated with the histopathological diagnosis. The sensitivity, specificity and diagnostic accuracy for the diagnosis of malignancy were 90.47, 100 and 99.14%. Our study demonstrates the feasibility and applicability of pattern analysis in diagnosing thyroid lesions, which could be easily reproducible.
authors.affiliation: Department of Pathology, VMKV Medical College, Salem, Tamil Nadu, India. medicoprakash@yahoo.com
authors.forename: Prakash H
authors.initials: PH
authors.lastname: MuddeGowda
authors.forename: Jyothi
authors.initials: J
authors.lastname: Lingegowda
authors.forename: Rajesh
authors.initials: R
authors.lastname: Natesan
authors.forename: Ramkumar
authors.initials: R
authors.lastname: Kurpad
mesh_terms: D000236:Adenoma / Q000175:diagnosis* / Q000473:pathology; D018249:Adenoma, Oxyphilic / Q000175:diagnosis* / Q000473:pathology; D044963:Biopsy, Fine-Needle; D002277:Carcinoma / Q000175:diagnosis* / Q000473:pathology; D006042:Goiter / Q000175:diagnosis* / Q000473:pathology; D050031:Hashimoto Disease / Q000175:diagnosis / Q000473:pathology; D006801:Humans; D015588:Observer Variation; D012189:Retrospective Studies; D013964:Thyroid Neoplasms / Q000175:diagnosis* / Q000473:pathology