title: [Diagnostic value of 64-slice spiral computed tomographic angiography in vertebral artery stenosis: a meta-analysis].
abstract: OBJECTIVE
  To evaluate the diagnostic value of 64-slice spiral computed tomographic angiography (CTA) in vertebral artery stenosis through a meta-analysis of the relevant data.
  
  
  METHODS
  A database search of Cochrane Library, PubMed, EBSCO, CBM-disc and CNKI was performed to identify the relevant English and Chinese language articles with such keywords as 64-slice computer tomography, angiography and vertebral artery stenosis. Quality evaluation, heterogeneity test and sensitivity and specificity to the qualified original data were conducted. Summary receiver operating characteristic (SROC) curve, the area under curve (AUC) and diagnostic odds ratio (DROC) were also calculated.
  
  
  RESULTS
  A total of 4 studies were eligible for meta-analysis. Among them, 1 was graded as A and 3 were graded as B. No heterogeneity was found based upon a fixed effect model. For vertebral artery stenosis > or = 50%, the pooled weighted sensitivity, specificity, DROC and SROC AUC was 0.98 (0.94 -1.00), 0.93 (0.89 -0.96), 526.33 and 0.9899 respectively; while for vertebral artery stenosis > or = 50%, the parameters were 0.98 (0.91 - 1.00), 0.97 (0.94 -0.99), 838.40 and 0.9932 respectively.
  
  
  CONCLUSIONS
  64-slice spiral CTA has such a high level of accuracy, sensitivity and specificity in the non-invasive diagnosis of vertebral artery stenosis.
authors.affiliation: Department of Neurology, First Affiliated Hospital, Guangxi Medical University, Nanning 530021, China.
authors.forename: Li-Ya
authors.initials: LY
authors.lastname: Wu
authors.forename: Chao
authors.initials: C
authors.lastname: Qin
authors.forename: Zi-Ming
authors.initials: ZM
authors.lastname: Ye
authors.forename: Yu-Jia
authors.initials: YJ
authors.lastname: Mei
authors.forename: Hong
authors.initials: H
authors.lastname: Zhou
authors.forename: Bang-Li
authors.initials: BL
authors.lastname: Hu
mesh_terms: D006801:Humans; D036542:Tomography, Spiral Computed / Q000379:methods*; D014715:Vertebrobasilar Insufficiency / Q000000981:diagnostic imaging*