title: Recent advances in the biology and chemistry of the flavaglines.
abstract: The flavaglines are a family of plant natural products that induce potent anticancer and neuroprotective activities. This review summarizes recent synthetic approaches to flavaglines and the current status of their pharmacological properties.
authors.affiliation: Therapeutic Innovation Laboratory, UMR 7200, CNRS/Université de Strasbourg, 67401 Illkirch, France.
authors.forename: Nigel
authors.initials: N
authors.lastname: Ribeiro
authors.forename: Frédéric
authors.initials: F
authors.lastname: Thuaud
authors.forename: Canan
authors.initials: C
authors.lastname: Nebigil
authors.forename: Laurent
authors.initials: L
authors.lastname: Désaubry
mesh_terms: D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D001688:Biological Products / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy / Q000378:metabolism; D010944:Plants / Q000737:chemistry*; D015398:Signal Transduction / Q000187:drug effects
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D001688:Biological Products