title: [Glucocorticoids in rheumatoid arthritis: almost always or hardly ever?].
abstract: The use of glucocorticoids in rheumatoid arthritis has been the source of frequent debate in the last decades. There is evidence on its anti-inflammatory capacity and its power to decrease radiologic progression, particularly if used in recent onset rheumatoid arthritis. However, there are still some voices questioning its use. Their arguments are its potential side-effects, especially when the glucocorticoids are used in high doses and/or for extended periods of time. In this review, we will try to summarize the evidence regarding this issue, from the beginning of the discussion in the fifties to the last releases.
authors.affiliation: Servicio de Reumatología, Hospital Universitario Virgen del Rocío, Sevilla, España. elenaabm@hotmail.com
authors.forename: Elena Alonso
authors.initials: EA
authors.lastname: Blanco-Morales
authors.forename: José María
authors.initials: JM
authors.lastname: Bravo-Ferrer Acosta
authors.forename: Esteban
authors.initials: E
authors.lastname: Rubio Romero
authors.forename: Eulalia
authors.initials: E
authors.lastname: Gil González
authors.forename: María Ángeles
authors.initials: MÁ
authors.lastname: Gantes Pedraza
mesh_terms: D018501:Antirheumatic Agents / Q000009:adverse effects / Q000627:therapeutic use*; D001172:Arthritis, Rheumatoid / Q000175:diagnosis / Q000188:drug therapy*; D042241:Early Diagnosis; D005938:Glucocorticoids / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D055502:Secondary Prevention
chemical_list: D018501:Antirheumatic Agents; D005938:Glucocorticoids