title: Production of 61Cu using natural cobalt target and its separation using ascorbic acid and common anion exchange resin.
abstract: (61)Cu was produced by (nat)Co(α, xn)(61)Cu reaction. (61)Cu production yield was 89.5 MBq/μAh (2.42 mCi/μAh) at the end of irradiation (EOI). A simple radiochemical separation method using anion exchange resin and ascorbic acid has been employed to separate the product radionuclide from inactive target material and co-produced non-isotopic impurities. The radiochemical separation yield was about 90%. Radiochemical purity of (61)Cu was >99% 1 h after EOI. Final product was suitable for making complex with N(2)S(2) type of ligands.
authors.affiliation: Radiopharmaceuticals Laboratory, Board of Radiation and Isotope Technology, Variable Energy Cyclotron Centre, Kolkata, India.
authors.forename: Sujata Saha
authors.initials: SS
authors.lastname: Das
authors.forename: Sankha
authors.initials: S
authors.lastname: Chattopadhyay
authors.forename: Luna
authors.initials: L
authors.lastname: Barua
authors.forename: Malay Kanti
authors.initials: MK
authors.lastname: Das
mesh_terms: D000837:Anion Exchange Resins; D001205:Ascorbic Acid; D003035:Cobalt / Q000737:chemistry* / Q000528:radiation effects; D003301:Copper Radioisotopes / Q000302:isolation & purification*; D017357:Cyclotrons; D009686:Nuclear Physics; D019275:Radiopharmaceuticals / Q000138:chemical synthesis* / Q000302:isolation & purification
chemical_list: D000837:Anion Exchange Resins; D003301:Copper Radioisotopes; D019275:Radiopharmaceuticals; D003035:Cobalt; D001205:Ascorbic Acid