title: [Contribution of the Study Center of the German Surgical Society to evidence based surgery].
abstract: Since the Study Center of the German Surgical Society (SDGC) was established in 2003 it has been supporting surgeons to implement their ideas for multicenter randomized studies. Assistance is provided for development (sample size calculation, protocol, funding application) implementation (submission to ethics committee, data management, monitoring) and analysis (statistical analysis, publication) in close collaboration with biometricians and data managers. Currently more than 2,500 patients have been included in 11 trials. The most complex SDGC study (SYNCHRONOUS) so far with up to 80 participating centers has been activated in September 2011. Furthermore, there is an increasing relevance for systematic reviews and meta analyses with regard to the development of studies and aggregation of results. For this reason a systematic review working group was established within the SDGC. To date 13 publications have been completed and 8 more are underway.
authors.affiliation: Studienzentrum der Deutschen Gesellschaft für Chirurgie, Heidelberg, Germany.
authors.forename: C
authors.initials: C
authors.lastname: Fink
authors.forename: T
authors.initials: T
authors.lastname: Keck
authors.forename: I
authors.initials: I
authors.lastname: Rossion
authors.forename: J
authors.initials: J
authors.lastname: Weitz
authors.forename: M K
authors.initials: MK
authors.lastname: Diener
authors.forename: M W
authors.initials: MW
authors.lastname: Büchler
authors.forename: P
authors.initials: P
authors.lastname: Knebel
mesh_terms: D019317:Evidence-Based Medicine; D005858:Germany; D006801:Humans; D015337:Multicenter Studies as Topic; D016032:Randomized Controlled Trials as Topic; D012107:Research Design; D012109:Research Support as Topic; D012955:Societies, Medical
references.citation: Trials. 2006 Sep 01;7:27
references.pmid: 16948853
references.citation: Zentralbl Chir. 2011 Apr;136(2):87-9
references.pmid: 21500149
references.citation: Lancet. 2009 Sep 26;374(9695):1089-96
references.pmid: 19782874
references.citation: Trials. 2011 Mar 22;12:84
references.pmid: 21426543
references.citation: Dig Surg. 2003;20(4):263-9
references.pmid: 12748428
references.citation: Lancet. 2011 Apr 30;377(9776):1514-22
references.pmid: 21529927
references.citation: Chirurg. 2007 Oct;78(10):938-44
references.pmid: 17805496
references.citation: Langenbecks Arch Surg. 2011 Jan;396(1):41-52
references.pmid: 20963439
references.citation: Gastroenterology. 2010 May;138(5):1714-26
references.pmid: 20100481
references.citation: Ann Surg. 2009 Apr;249(4):576-82
references.pmid: 19300233
references.citation: Trials. 2011 Feb 08;12:34
references.pmid: 21303515
references.citation: J Gastrointest Surg. 2009 Mar;13(3):558-68
references.pmid: 18622655
references.citation: Trials. 2007 Feb 27;8:7
references.pmid: 17326823
references.citation: Chirurg. 2006 Jun;77(6):531-4
references.pmid: 16583205
references.citation: J Gastrointest Surg. 2009 Apr;13(4):745-51
references.pmid: 19083070
references.citation: Chirurg. 2010 May;81(5):454-71
references.pmid: 20020091
references.citation: Surgery. 2009 Sep;146(3):444-61
references.pmid: 19715801
references.citation: Langenbecks Arch Surg. 2006 Apr;391(2):61-7
references.pmid: 16292684
references.citation: Ann Surg. 2010 May;251(5):843-56
references.pmid: 20395846
references.citation: Cochrane Database Syst Rev. 2011 May 11;(5):CD006053
references.pmid: 21563148
references.citation: Langenbecks Arch Surg. 2011 Oct;396(7):1061-6
references.pmid: 21559859
references.citation: Chirurg. 2007 Apr;78(4):362-6
references.pmid: 17393127
references.citation: Langenbecks Arch Surg. 2012 Dec;397(8):1193-9
references.pmid: 21424797
references.citation: Surgery. 2009 Jun;145(6):590-7
references.pmid: 19486757
references.citation: Am J Surg. 2007 Feb;193(2):171-83
references.pmid: 17236843
references.citation: Lancet. 2009 Sep 26;374(9695):1097-104
references.pmid: 19782875
references.citation: Br J Surg. 2008 Apr;95(4):424-32
references.pmid: 18314921
references.citation: Trials. 2007 Sep 18;8:22
references.pmid: 17877805