title: Morbidity and mortality of cytoreductive surgery with hyperthermic intraperitoneal chemotherapy: national cancer institute, Mexico city, Mexico.
abstract: Peritoneal carcinomatosis (PC) is generally considered a lethal disease, with a poor prognosis. Cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) has emerged as a new approach for peritoneal surface disease. This study investigated the early experience with this combined modality treatment at a single institute. From January 2007 to March 2010, 24 patients were treated After aggressive CS, with HIPEC (cisplatin 25 mg/m(2)/L and mitomycin C 3.3 mg/m(2)/L was administered for 90-minutes at 40.5° C). These data suggest that aggressive CRS with HIPEC for the treatment of PC may result in low mortality and acceptable morbidity. Rigorous patient selection, appropriate and prudent operative procedures were associated with encouraging results in our experience.
authors.affiliation: Department of Surgical Oncology, National Cancer Institute, San Fernando No. 22 Colonia Seccion XVI, Tlalpan, 14080 Mexico City, DF, Mexico.
authors.forename: Horacio N
authors.initials: HN
authors.lastname: López-Basave
authors.forename: Flavia
authors.initials: F
authors.lastname: Morales-Vásquez
authors.forename: J M
authors.initials: JM
authors.lastname: Ruiz Molina
authors.forename: Aaron
authors.initials: A
authors.lastname: González-Enciso
authors.forename: Silvio A
authors.initials: SA
authors.lastname: Namendys-Silva
authors.forename: Juan M
authors.initials: JM
authors.lastname: Medina Castro
authors.forename: Gonzalo
authors.initials: G
authors.lastname: Montalvo-Esquivel
authors.forename: Angel
authors.initials: A
authors.lastname: Herrera-Gómez
authors.forename: Jaime G
authors.initials: JG
authors.lastname: De la Garza Salazar
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