title: [Microbiological analysis of late infected hip arthroplasty in 62 cases].
abstract: OBJECTIVE
  To review the type and number of pathogens and their antibiotic sensitivity in patients with late infected total joint replacement so as to offer guidance for the choice of antibiotics.
  
  
  METHODS
  A retrospective analysis was conducted for 62 patients whose suspected specimens were obtained intra-operatively during a total hip arthroplasty since January 2002 to August 2010 at our department. Their demographic data, bacterial species and antibiotic sensitivity profiles were recorded.
  
  
  RESULTS
  Among 62 cases, the cultures were tested positive in 48 cases; the most common bacteria was Gram-positive bacteria (74%). And coagulase-negative staphylococci and Staphylococcus aureus accounted for 62.9% of all bacterial cultures. And the ratio of methicillin-resistant Staphylococcus was 41.18%.
  
  
  CONCLUSIONS
  The late infection of total hip arthroplasty is mainly caused by Gram-positive bacteria. Antibiotic treatment for late periprosthetic infection should be guided by the findings of drug susceptibility. Vancomycin may be used as a primary agent for the treatment of infected hip arthroplasty.
authors.affiliation: Department of Orthopedic Surgery, General Hospital of Chinese PLA, Beijing 100853, China.
authors.forename: Xiang-Cheng
authors.initials: XC
authors.lastname: Lu
authors.forename: Yong-Gang
authors.initials: YG
authors.lastname: Zhou
authors.forename: Yan
authors.initials: Y
authors.lastname: Wang
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D019644:Arthroplasty, Replacement, Hip / Q000009:adverse effects*; D004352:Drug Resistance, Microbial; D005260:Female; D006094:Gram-Positive Bacteria / Q000302:isolation & purification; D006801:Humans; D008297:Male; D008875:Middle Aged; D016459:Prosthesis-Related Infections / Q000382:microbiology*; D012189:Retrospective Studies; D014640:Vancomycin / Q000494:pharmacology; D055815:Young Adult
chemical_list: D000900:Anti-Bacterial Agents; D014640:Vancomycin