title: Signal amplification by magnetic force on polydiacetylene supramolecules for detection of prostate cancer.
abstract: A method in which a permanent magnet is introduced onto polydiacetylene (PDA) vesicle chips is introduced for enhancement of the fluorescence of PDA vesicles. This strategy can be applied to general antibody-based PDA vesicle chips to detect clinically important biomarkers for disease diagnosis.
authors.affiliation: Nanobiotechnology Laboratory, Department of Chemical and Biological Engineering, Korea University, Seoul, 136-713, Korea.
authors.forename: Il Kyoung
authors.initials: IK
authors.lastname: Kwon
authors.forename: Min Sun
authors.initials: MS
authors.lastname: Song
authors.forename: Sang Ho
authors.initials: SH
authors.lastname: Won
authors.forename: Seung Phill
authors.initials: SP
authors.lastname: Choi
authors.forename: Moonil
authors.initials: M
authors.lastname: Kim
authors.forename: Sang Jun
authors.initials: SJ
authors.lastname: Sim
mesh_terms: D055910:Antibodies, Immobilized; D000911:Antibodies, Monoclonal; D015374:Biosensing Techniques / Q000379:methods* / Q000706:statistics & numerical data; D001710:Biotin; D005453:Fluorescence; D006801:Humans; D060328:Magnetic Phenomena; D008297:Male; D008855:Microscopy, Electron, Scanning; D000078789:Polyacetylene Polymer; D011108:Polymers; D053279:Polyynes; D017430:Prostate-Specific Antigen / Q000097:blood; D011471:Prostatic Neoplasms / Q000097:blood / Q000175:diagnosis*; D019809:Streptavidin; D000514:alpha 1-Antichymotrypsin / Q000097:blood; D000511:alpha-Macroglobulins / Q000032:analysis
chemical_list: D055910:Antibodies, Immobilized; D000911:Antibodies, Monoclonal; D000078789:Polyacetylene Polymer; D011108:Polymers; D000514:alpha 1-Antichymotrypsin; D000511:alpha-Macroglobulins; D053279:Polyynes; C082361:polydiacetylene; D001710:Biotin; D019809:Streptavidin; D017430:Prostate-Specific Antigen