title: Immunosuppressive small molecule discovered by structure-based virtual screening for inhibitors of protein-protein interactions.
authors.affiliation: Eidgenössische Technische Hochschule (ETH) Zürich, Department of Chemistry and Applied Biosciences, Wolfgang-Pauli-Strasse 10, 8093 Zürich, Switzerland.
authors.forename: Tim
authors.initials: T
authors.lastname: Geppert
authors.forename: Stefanie
authors.initials: S
authors.lastname: Bauer
authors.forename: Jan A
authors.initials: JA
authors.lastname: Hiss
authors.forename: Elea
authors.initials: E
authors.lastname: Conrad
authors.forename: Michael
authors.initials: M
authors.lastname: Reutlinger
authors.forename: Petra
authors.initials: P
authors.lastname: Schneider
authors.forename: Martin
authors.initials: M
authors.lastname: Weisel
authors.forename: Bernhard
authors.initials: B
authors.lastname: Pfeiffer
authors.forename: Karl-Heinz
authors.initials: KH
authors.lastname: Altmann
authors.forename: Zoe
authors.initials: Z
authors.lastname: Waibler
authors.forename: Gisbert
authors.initials: G
authors.lastname: Schneider
mesh_terms: D001665:Binding Sites; D003198:Computer Simulation; D018360:Crystallography, X-Ray; D015195:Drug Design; D006801:Humans; D006860:Hydrogen Bonding; D007166:Immunosuppressive Agents / Q000737:chemistry*; D016898:Interferon-alpha / Q000037:antagonists & inhibitors / Q000378:metabolism*; D009682:Magnetic Resonance Spectroscopy; D060066:Protein Interaction Maps; D017434:Protein Structure, Tertiary; D053633:Receptor, Interferon alpha-beta / Q000037:antagonists & inhibitors / Q000378:metabolism*; D054852:Small Molecule Libraries / Q000737:chemistry*; D020349:Surface Plasmon Resonance
chemical_list: D007166:Immunosuppressive Agents; D016898:Interferon-alpha; D054852:Small Molecule Libraries; D053633:Receptor, Interferon alpha-beta