title: Molecular network topology and reliability for multipurpose diagnosis.
abstract: This investigation proposes the use of molecular network topology for drug delivery and diagnosis network design. Three modules of molecular network topologies, such as bus, star, and ring networks, are designed and manipulated based on a micro- and nanoring resonator system. The transportation of the trapping molecules by light in the network is described and the theoretical background is reviewed. The quality of the network is analyzed and calculated in terms of signal transmission (ie, signal to noise ratio and crosstalk effects). Results obtained show that a bus network has advantages over star and ring networks, where the use of mesh networks is possible. In application, a thin film network can be fabricated in the form of a waveguide and embedded in artificial bone, which can be connected to the required drug targets. The particular drug/nutrient can be transported to the required targets via the particular network used.
authors.affiliation: Hybrid Computing Research Laboratory, Faculty of Engineering, King Mongkut’s Institute of Technology Ladkrabang, Bangkok, Thailand [corrected].
authors.forename: N
authors.initials: N
authors.lastname: Moongfangklang
authors.forename: M A
authors.initials: MA
authors.lastname: Jalil
authors.forename: K
authors.initials: K
authors.lastname: Innate
authors.forename: S
authors.initials: S
authors.lastname: Mitatha
authors.forename: J
authors.initials: J
authors.lastname: Ali
authors.forename: P P
authors.initials: PP
authors.lastname: Yupapin
mesh_terms: D016503:Drug Delivery Systems / Q000295:instrumentation* / Q000379:methods*; D006801:Humans; D008962:Models, Theoretical; D025202:Molecular Diagnostic Techniques / Q000295:instrumentation* / Q000379:methods*; D050997:Nanomedicine / Q000295:instrumentation* / Q000379:methods*; D009415:Nerve Net; D052898:Optical Tweezers; D012815:Signal Processing, Computer-Assisted; D059629:Signal-To-Noise Ratio
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