title: Hepatocellular carcinoma of the liver.
abstract: Primary cancer of the liver, hepatocellular carcinoma (HCC), is an extremely deadly cancer, with very poor 5 year survivals, following diagnosis. The poor outcomes are believed to be due, in part, to the late times in which the cancers are usually first detected. Improved methods for early detection have thus become a top priority in the management of liver cancer. This Chapter reviews current methods of detection as well as leading new methods. Possible explanations as to why there are so many markers that are being discovered, but so few that make it to validation are discussed.
authors: Department of Microbiology and Immunology, Drexel University College of Medicine and Hepatitis B Foundation, Pennsylvania Biotechnology Center, Doylestown, PA, USA. timothy.block@Drexelmed.edu
authors: Timothy
authors: T
authors: Block
authors: Anand S
authors: AS
authors: Mehta
authors: W Thomas
authors: WT
authors: London
mesh_terms: D014408:Biomarkers, Tumor / Q000378:metabolism; D006528:Carcinoma, Hepatocellular / Q000175:diagnosis*; D006801:Humans; D008113:Liver Neoplasms / Q000175:diagnosis*; D012307:Risk Factors
chemical_list: D014408:Biomarkers, Tumor