title: Intravenous thrombolysis in Sneddon's syndrome.
abstract: Sneddon's syndrome (SS) is an uncommon disorder, characterized by the association of ischemic stroke and widespread livedo reticularis. The treatment options for SS to prevent stroke recurrence and future disability include antiplatelet therapy, anticoagulation, or immunosuppression. We describe a patient with SS who presented with an acute ischemic stroke, and was treated with intravenous recombinant tissue-plasminogen activator with significant neurologic improvement. To our knowledge this is the first report of the use of thrombolysis in SS patients with acute ischemic stroke. It suggests that thrombolytic therapy might be safe and effective in these patients.
authors: Department of Radiology, The 2nd Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou, China.
authors: Jianzhong
authors: J
authors: Sun
authors: Fanhui
authors: F
authors: Zhang
authors: Feng
authors: F
authors: Gao
authors: Jihua
authors: J
authors: Wang
authors: Magdy
authors: M
authors: Selim
authors: Min
authors: M
authors: Lou
mesh_terms: D000328:Adult; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D018860:Sneddon Syndrome / Q000175:diagnosis* / Q000188:drug therapy*; D015912:Thrombolytic Therapy; D010959:Tissue Plasminogen Activator / Q000008:administration & dosage*
chemical_list: D010959:Tissue Plasminogen Activator