title: Multicentric infiltrative lipoma in a farmed Mediterranean seabass Dicentrarchus labrax: a pathological and biochemical case study.
abstract: A tumour diagnosed as multicentric infiltrative lipoma affecting a single farmed seabass is described. The fish had 3 masses on the lateral side of its back, deforming the skin surface. The masses showed a tendency to invade the underlying musculature. Histologically, the neoplasm consisted of differentiated adipocytes. Biochemically, the neoplastic tissue showed lower values of monounsaturated fatty acids and higher values of polyunsaturated fatty acids compared with adjacent normal muscular tissue, particularly of the n3 series, such as eicosapentanoic (C20:5n3) and docosahexanoic (C22:6n3) acids. Data obtained suggest a metabolic disturbance in the lipid component of the muscular tissue metabolic pathway, which could be the starting point to promote lipoma formation. This is the first report of lipoma in Mediterranean seabass.
authors: Department of Veterinary Public Health, Faculty of Veterinary Medicine, University of Messina, Polo Universitario dell'Annunziata, 98168 Messina, Italy. marinof@unime.it
authors: F
authors: F
authors: Marino
authors: B
authors: B
authors: Chiofalo
authors: G
authors: G
authors: Mazzullo
authors: A
authors: A
authors: Panebianco
mesh_terms: D000818:Animals; D001492:Bass; D005227:Fatty Acids / Q000378:metabolism; D005393:Fish Diseases / Q000378:metabolism / Q000473:pathology*; D008067:Lipoma / Q000378:metabolism / Q000473:pathology / Q000662:veterinary*
chemical_list: D005227:Fatty Acids