title: From filopodia to synapses: the role of actin-capping and anti-capping proteins.
abstract: Actin-capping and anti-capping proteins are crucial regulators of actin dynamics. Recent studies have indicated that these proteins may be heavily involved in all stages of synaptogenesis, from the emergence of filopodia, through neuritogenesis and synaptic contact stabilization, to the structural changes occurring at the synapse during potentiation phenomena. In this review, we focus on recent evidence pointing to an active role of actin-capping and anti-capping proteins in orchestrating the processes controlling neuronal connectivity and plasticity.
authors: Department of Medical Pharmacology and CNR Institute of Neuroscience, University of Milan, Milano, Italy.
authors: Elisabetta
authors: E
authors: Menna
authors: Giuliana
authors: G
authors: Fossati
authors: Giorgio
authors: G
authors: Scita
authors: Michela
authors: M
authors: Matteoli
mesh_terms: D051344:Actin Capping Proteins / Q000235:genetics / Q000378:metabolism*; D000199:Actins / Q000378:metabolism*; D009473:Neuronal Plasticity / Q000502:physiology; D009474:Neurons / Q000166:cytology / Q000502:physiology; D011554:Pseudopodia / Q000378:metabolism* / Q000648:ultrastructure; D018091:Receptors, AMPA / Q000378:metabolism; D016194:Receptors, N-Methyl-D-Aspartate / Q000378:metabolism; D013569:Synapses / Q000378:metabolism*
chemical_list: D051344:Actin Capping Proteins; D000199:Actins; D018091:Receptors, AMPA; D016194:Receptors, N-Methyl-D-Aspartate