title: Carriage of Staphylococcus aureus in the nose of patients on regular dialysis treatment using hemodialysis catheters.
abstract: In the hemodialysis population, the incidence of Staphylococcus aureus colonization has been documented to be as high as 80%; effective prophylaxis of vascular access infection and bacteremia is a worthwhile goal in the management of hemodialysis population. Surveillance of 50 hemodialysis patients for S. aureus-positive nasal cultures was performed by monthly nasal swabs over a 12-month period. All patients were performing dialysis using hemodialysis catheters thrice weekly. All positive cultures were treated with a prophylactic antibiotic regimen. Thirty-one patients (62%) had one or more positive cultures. The surveillance period was longer in the S. aureus nasal carriers (p < 0.01). The frequency of positive cultures correlated with the duration of surveillance (p < 0.05). The incidence of S. aureus bacteremia was greater in patients with three or more positive cultures (p < 0.05). This study suggests that continuous surveillance for S. aureus nasal colonization is essential to properly identify all hemodialysis patients using catheters at risk of developing S. aureus bacteremias.
authors: Internal Medicine and Nephrology Department, Cairo University, Cairo, Egypt. hodamamoun@yahoo.com
authors: Hoda Abdel Hamid
authors: HA
authors: Maamoun
authors: Amin Roshdy
authors: AR
authors: Soliman
authors: Rasha
authors: R
authors: El Sherif
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D016470:Bacteremia / Q000517:prevention & control; D057785:Catheters; D002408:Catheters, Indwelling; D004866:Equipment Contamination / Q000517:prevention & control*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009666:Nose / Q000382:microbiology*; D006435:Renal Dialysis / Q000379:methods*; D013203:Staphylococcal Infections / Q000517:prevention & control; D013211:Staphylococcus aureus
chemical_list: D000900:Anti-Bacterial Agents