title: Spiro[pyrrolidine-2,3'-oxindole] derivatives synthesized by novel regionselective 1,3-dipolar cycloadditions.
abstract: A series of spiro-oxindole derivatives was synthesized by novel regioselective 1,3-dipolar cycloadditions of isatin, α-amino acids, and (E)-β-aryl-nitro-olefins. Regioisomers were produced in each reaction and the major products showed different regioselectivity compared to previously reported spiro-oxindole derivatives.
authors: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650204, China. gangchen@xsyu.edu.cn
authors: Gang
authors: G
authors: Chen
authors: Jing
authors: J
authors: Yang
authors: Suo
authors: S
authors: Gao
authors: Hongping
authors: H
authors: He
authors: Shunlin
authors: S
authors: Li
authors: Yingtong
authors: Y
authors: Di
authors: Ying
authors: Y
authors: Chang
authors: Yang
authors: Y
authors: Lu
authors: Xiaojiang
authors: X
authors: Hao
mesh_terms: D000475:Alkenes / Q000737:chemistry; D000596:Amino Acids / Q000737:chemistry; D002625:Chemistry, Organic / Q000379:methods*; D018360:Crystallography, X-Ray; D003500:Cyclization; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry; D007510:Isatin / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D000078183:Oxindoles; D011759:Pyrrolidines / Q000138:chemical synthesis* / Q000737:chemistry; D013141:Spiro Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D000475:Alkenes; D000596:Amino Acids; D007211:Indoles; D000078183:Oxindoles; D011759:Pyrrolidines; D013141:Spiro Compounds; C022960:2-oxindole; D007510:Isatin; C032519:pyrrolidine