title: Endovascular treatment strategies for acute ischemic stroke.
abstract: The limitations of intravenous thrombolysis therapy have paved the way for the development of novel endovascular technologies for use in the setting of acute stroke. These technologies range from direct intraarterial thrombolysis to various thrombus disruption or retrieval devices to angioplasty and stenting. The tools in the armamentarium of the neuroendovascular interventionalist enable fast, effective revascularization to be offered to a wider population of patients that may otherwise have few therapeutic options available to them. In this paper, we review the current state-of-the-art in neuroendovascular intervention for acute ischemic stroke. Particular emphasis is placed on delineating the indications and outcomes for use of these various technologies.
authors: Department of Neurological Surgery, Columbia University Medical Center, New York, NY 10032, USA. jae2109@columbia.edu
authors: Jason A
authors: JA
authors: Ellis
authors: Brett E
authors: BE
authors: Youngerman
authors: Randall T
authors: RT
authors: Higashida
authors: Dorothea
authors: D
authors: Altschul
authors: Philip M
authors: PM
authors: Meyers
mesh_terms: D000800:Angioplasty, Balloon; D002545:Brain Ischemia / Q000150:complications / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*; D002548:Cerebral Revascularization; D017128:Embolectomy; D057510:Endovascular Procedures; D005343:Fibrinolytic Agents / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D007269:Injections, Intra-Arterial; D007275:Injections, Intravenous; D016032:Randomized Controlled Trials as Topic; D015607:Stents; D020521:Stroke / Q000188:drug therapy / Q000209:etiology / Q000601:surgery / Q000628:therapy*; D017131:Thrombectomy; D015912:Thrombolytic Therapy; D010959:Tissue Plasminogen Activator / Q000627:therapeutic use
chemical_list: D005343:Fibrinolytic Agents; D010959:Tissue Plasminogen Activator