title: [Evidence from large clinical trials for Japanese hypertensive patients].
abstract: Large-scale clinical trials for the hypertensive patients have been carried out in Japan. Double-blind, placebo-controlled large clinical trials in Europe and USA showed that antihypertensive drugs prevented cardiovascular disease. Recently large clinical trials carried out in Japan. These clinical trials have shown that the onset rate of the heart vascular disease in Japanese hypertensive patients, the factor which influenced the onset of the cardiovascular disease, and the suppressant effect of cardiovascular disease of different antihypertensive drug class.
authors: Department of Integrated Medicine and Informatics, Ehime Graduate School of Medicine.
authors: Takafumi
authors: T
authors: Okura
authors: Jitsuo
authors: J
authors: Higaki
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000959:Antihypertensive Agents / Q000627:therapeutic use*; D002318:Cardiovascular Diseases / Q000517:prevention & control*; D002986:Clinical Trials as Topic; D019317:Evidence-Based Medicine; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D008875:Middle Aged
chemical_list: D000959:Antihypertensive Agents