title: Terminalia chebula mediated green and rapid synthesis of gold nanoparticles.
abstract: Biologically inspired experimental process in synthesising nanoparticles is of great interest in present scenario. Biosynthesis of nanoparticles is considered to be one of the best green techniques in synthesising metal nanoparticles. Here, an in situ green biogenic synthesis of gold nanoparticles using aqueous extracts of Terminalia chebula as reducing and stabilizing agent is reported. Gold nanoparticles were confirmed by surface plasmon resonance in the range of 535 nm using UV-visible spectrometry. TEM analysis revealed that the morphology of the particles thus formed contains anisotropic gold nanoparticles with size ranging from 6 to 60 nm. Hydrolysable tannins present in the extract of T. chebula are responsible for reductions and stabilization of gold nanoparticles. Antimicrobial activity of gold nanoparticles showed better activity towards gram positive S. aureus compared to gram negative E. coli using standard well diffusion method.
authors: Trace Elements Speciation Research Laboratory, Environmental and Analytical Chemistry Division, School of Advanced Sciences, VIT University, Vellore 632 014, Tamilnadu, India.
authors: Kesarla Mohan
authors: KM
authors: Kumar
authors: Badal Kumar
authors: BK
authors: Mandal
authors: Madhulika
authors: M
authors: Sinha
authors: Varadhan
authors: V
authors: Krishnakumar
mesh_terms: D000042:Absorption / Q000187:drug effects; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D003102:Colloids; D004926:Escherichia coli / Q000187:drug effects; D006046:Gold / Q000737:chemistry*; D055772:Green Chemistry Technology / Q000379:methods*; D053768:Metal Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D008826:Microbial Sensitivity Tests; D036103:Nanotechnology / Q000379:methods*; D010936:Plant Extracts / Q000737:chemistry; D011199:Potentiometry; D012996:Solutions; D013056:Spectrophotometry, Ultraviolet; D017550:Spectroscopy, Fourier Transform Infrared; D013211:Staphylococcus aureus / Q000187:drug effects; D029766:Terminalia / Q000737:chemistry*; D014961:X-Ray Diffraction
chemical_list: D000900:Anti-Bacterial Agents; D003102:Colloids; D010936:Plant Extracts; D012996:Solutions; D006046:Gold