title: The isolation of a metastable conglomerate using a combined computational and controlled crystallization approach.
abstract: While the use of additives to control the crystallization of polymorphs is well known, similar methodology to promote the crystallization of a metastable conglomerate over a stable racemic compound in enantiomeric systems has not been reported. Here we demonstrate this phenomenon in the case of 2-chloromandelic acid.
authors: School of Chemical Engineering and Analytical Science, University of Manchester, Oxford Road, Manchester M13 9PL, UK. roger.davey@manchester.ac.uk
authors: Roger J
authors: RJ
authors: Davey
authors: Ghazala
authors: G
authors: Sadiq
authors: Kevin
authors: K
authors: Back
authors: Laura
authors: L
authors: Wilkinson
authors: Colin C
authors: CC
authors: Seaton
mesh_terms: D003460:Crystallization; D006860:Hydrogen Bonding; D008333:Mandelic Acids / Q000737:chemistry*; D008968:Molecular Conformation; D013237:Stereoisomerism; D014961:X-Ray Diffraction
chemical_list: C541344:2-chloromandelic acid; D008333:Mandelic Acids