title: Long-term outcomes after native tissue vs. biological graft-augmented repair in the posterior compartment.
abstract: OBJECTIVE
  We aimed to compare the outcomes of native tissue vs. biological graft-augmented repair in the posterior compartment. We hypothesized that the addition of graft would result in superior anatomic and functional outcomes.
  
  
  METHODS
  A retrospective review of posterior repairs between 2001 and 2008 was performed to compare the anatomic and functional outcomes between native tissue and graft-augmented techniques. Mann-Whitney and chi-square tests were used. Power calculation determined that 32 subjects were needed in each group.
  
  
  RESULTS
  One hundred twenty-four native tissue and 69 graft-augmented repairs were performed with a median follow-up of 35.8 months (range, 6 to 157 months). Anatomic success was similar for native tissue vs. graft (Bp < -1, 86% vs. 80% and Bp ≤ 0, 97% vs. 97%; all p > 0.05). Postoperative splinting and incomplete evacuation was greater in the graft group (splinting, 85% vs. 68%; p = 0.04 and incomplete evacuation, 85% vs. 64%; p = 0.03).
  
  
  CONCLUSIONS
  Long-term success of posterior repair is high. Graft augmentation does not appear to improve anatomic or functional outcomes.
authors: Division of Female Pelvic Medicine and Reconstructive Surgery, Department of Reproductive Medicine, University of California-San Diego, La Jolla, CA, USA. cara@jhu.edu
authors: Cara L
authors: CL
authors: Grimes
authors: Jasmine
authors: J
authors: Tan-Kim
authors: Emily L
authors: EL
authors: Whitcomb
authors: Emily S
authors: ES
authors: Lukacz
authors: Shawn A
authors: SA
authors: Menefee
mesh_terms: D000368:Aged; D001672:Biocompatible Materials; D003627:Data Interpretation, Statistical; D005260:Female; D005500:Follow-Up Studies; D013509:Gynecologic Surgical Procedures / Q000379:methods*; D006801:Humans; D008137:Longitudinal Studies; D008875:Middle Aged; D011184:Postoperative Period; D012189:Retrospective Studies; D016378:Tissue Transplantation / Q000379:methods*; D016896:Treatment Outcome; D014596:Uterine Prolapse / Q000601:surgery*; D014621:Vagina / Q000502:physiology / Q000601:surgery
chemical_list: D001672:Biocompatible Materials