title: Clinical and radiographic outcomes using local bone shavings as autograft in minimally invasive transforaminal lumbar interbody fusion.
abstract: BACKGROUND
  Transforaminal lumbar interbody fusion (TLIF) augmented with pedicle screw instrumentation has become a favored surgical treatment for management of lumbar degenerative disease and spondylolisthesis. Iliac crest bone graft has traditionally been used for interbody arthrodesis. Many substitutes for autograft have been suggested to reduce iliac crest graft morbidity. The present study was aimed to determine fusion rate and clinical outcome with local bone autograft drill shavings harvested during minimally invasive (MI) TLIF.
  
  
  METHODS
  A retrospective study of 40 patients who underwent MI-TLIF using a cage filled with local bone shavings and pedicle screw fixation with a minimum 1-year imaging follow-up was performed. Bone shavings were collected during surgery by use of a simple specimen trap device. Fusion was assessed with computed tomography scan with sagittal and coronal reconstructions. Clinical assessment was performed using patient-filled preoperative and postoperative Oswestry Disability Index (ODI) and leg and back pain visual analog scale (VAS) score.
  
  
  RESULTS
  The mean age at time of surgery was 54 years (range, 21 to 84 years). Clinical outcome was graded as excellent or good in 65% and 27% of patients, respectively, based on improvement in ODI and VAS. The mean ODI, leg, and back pain VAS score improved from 66, 6, and 9 to 30, 1, and 3 after surgery (P<0.005) Fusion was demonstrated on computed tomography scan in 67.5% of patients. Clinical outcome was graded as excellent or good in 92% of patients irrespective of the presence or absence of fusion (P=0.45).
  
  
  CONCLUSIONS
  Use of a cage filled with local bone shavings harvested using a specimen trap during MI-TLIF is simple and can result in up to a 70% fusion rate with good clinical outcome in 92% of patients. This is the first study assessing fusion rate with local bone shavings, and the results may help spine surgeons in choosing the best graft option for patients undergoing posterior lumbar fusion surgery.
authors: Department of Neurosurgery, Rush University Medical Center, Chicago, Illinois, USA.
authors: Manish K
authors: MK
authors: Kasliwal
authors: Harel
authors: H
authors: Deutsch
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001863:Bone Screws; D016025:Bone Transplantation / Q000379:methods*; D004185:Disability Evaluation; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D055959:Intervertebral Disc Degeneration / Q000175:diagnosis / Q000601:surgery*; D008159:Lumbar Vertebrae / Q000601:surgery*; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D019060:Minimally Invasive Surgical Procedures / Q000379:methods*; D010147:Pain Measurement; D011183:Postoperative Complications / Q000175:diagnosis; D012189:Retrospective Studies; D013123:Spinal Fusion / Q000379:methods*; D013168:Spondylolisthesis / Q000175:diagnosis / Q000601:surgery*; D020858:Tissue and Organ Harvesting / Q000379:methods*; D014057:Tomography, X-Ray Computed; D055815:Young Adult