title: Hip artroplasty: a transient reason not to be pregnant.
abstract: Metal implants corrode and release metal ions, cobalt and chromium, which, in turn, may cause systemic toxicity, mostly in the first few months from implantation of metal-on-metal hip arthroplasty. At the time of delivery, the placenta reduces the passage of cobalt and chromium ions released from metal-on-metal prosthesis. From a biomechanical view point, hip replacement should not be considered a contraindication for pregnancy or for spontaneous delivery, and does not seem to have any negative effects in terms of risk of dislocation, loosening, fracture, or revision surgery, neither negative effects on clinical and functional outcomes. The long-term biological consequences of exposure to Co-Cr particles and ions remain largely unknown.
authors: Centre for Sports and Exercise Medicine, Barts and The London School of Medicine and Dentistry, London, UK. n.maffulli@qmul.ac.uk
authors: Nicola
authors: N
authors: Maffulli
authors: Angelo
authors: A
authors: Del Buono
authors: Vincenzo
authors: V
authors: Denaro
mesh_terms: D019644:Arthroplasty, Replacement, Hip; D002857:Chromium / Q000009:adverse effects*; D003035:Cobalt / Q000009:adverse effects*; D005260:Female; D006622:Hip Prosthesis / Q000009:adverse effects*; D006801:Humans; D018811:Maternal Exposure / Q000009:adverse effects*; D008670:Metals / Q000009:adverse effects*; D011247:Pregnancy; D011474:Prosthesis Design; D012307:Risk Factors
chemical_list: D008670:Metals; D002857:Chromium; D003035:Cobalt