title: Evaluation of treatment planning system of brachytherapy according to dose to the rectum delivered.
abstract: The aim of this study was to assess the actual dose delivered to the rectum and compare it with the treatment planning system (TPS) reports. In this study, the dose delivered to the rectum was measured by semiconductor diode detectors (PTW, Germany). The factors that influence diode response were investigated as well. Calibration factors of diodes were measured weekly to investigate the effect of time interval on the accuracy of calibration. Then 40 applications of patients with cervix carcinoma were evaluated. Rectum dose was measured by means of rectal dosemeter and compared with the TPS-calculated dose. In this research, the differences between the measured and the calculated dose were investigated. The mean difference between the TPS-calculated dose and the measured dose was 6.5% (range: -22 to +39) for rectum. The TPS-calculated maximum dose was typically higher than the measured maximum dose. The study showed that the main reason for the difference was due to the movements of the patient and applicator shift in the elapsed time between the imaging and treatment stage. It is recommended that in vivo dosimetry should be performed in addition to treatment planning computation. In vivo dosimetry is a reliable solution to compare the planned and actual dose delivered to organs at risk.
authors: Department of Radiation Oncology, Cancer Research Center,  Tehran University of Medical Science, Tehran,  Iran.
authors: Mahmoud
authors: M
authors: Allahverdi
authors: Mina
authors: M
authors: Sarkhosh
authors: Mahdi
authors: M
authors: Aghili
authors: Ramin
authors: R
authors: Jaberi
authors: Akbar
authors: A
authors: Adelnia
authors: Ghazale
authors: G
authors: Geraily
mesh_terms: D001918:Brachytherapy; D005260:Female; D005858:Germany; D006801:Humans; D011874:Radiometry; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted; D012007:Rectum / Q000528:radiation effects*; D002583:Uterine Cervical Neoplasms / Q000532:radiotherapy*