title: Chance and necessity in the evolution of a bacterial pathogen.
abstract: The combination of genomic, epidemiological and evolutionary analyses provides a powerful toolbox for understanding how pathogens adapt to their human hosts. By sequencing 112 Burkholderia dolosa genomes from an outbreak among patients with cystic fibrosis, a new study documents evolution in action and identifies a set of genes that contributed to the pathogen's adaptation.
authors: BEACON Center for the Study of Evolution in Action, Michigan State University, East Lansing, USA. lenski@msu.edu
authors: Richard E
authors: RE
authors: Lenski
mesh_terms: D019117:Burkholderia / Q000235:genetics*; D019121:Burkholderia Infections / Q000382:microbiology*; D019143:Evolution, Molecular; D005798:Genes, Bacterial; D006801:Humans