title: A rare manifestation of cricopharyngeal myopathy presenting with dysphagia in sarcoidosis.
abstract: Sarcoidosis is a systemic inflammatory granulomatous disease that affects multiple organs in the body; however, dysphagia is a relatively rare manifestation at early stages. Dysphagia in sarcoidosis is attributed to many mechanisms, such as mediastinal lymphadenopathy, esophageal or laryngeal involvement, cranial neuropathy, and brainstem infiltration. In this article, we report an extremely rare case with sarcoidosis who presented with dysphagia due to isolated cricopharyngeal myopathy. The 75-year-old woman presented with slowly progressive swallowing difficulty and videofluorography showed insufficient opening of the upper esophageal sphincter. On presentation, she had no cranial nerve or central nervous system impairments. A cricopharyngeal myotomy was performed, and histopathological study revealed a significant inflammatory change with non-necrotizing granulomas within the muscle tissue. We concluded that this was a very rare case of sarcoidosis presenting with localized cricopharyngeal myopathy. Postoperatively, a contracture of the esophageal entrance was successfully released and the dysphagia was alleviated.
authors: Department of Otolaryngology, Kochi University School, Kochi, Japan.
authors: Kaori
authors: K
authors: Nishikubo
authors: Masamitsu
authors: M
authors: Hyodo
authors: Miyuki
authors: M
authors: Kawakami
authors: Taisuke
authors: T
authors: Kobayashi
mesh_terms: D000368:Aged; D003413:Cricoid Cartilage / Q000473:pathology* / Q000601:surgery; D003680:Deglutition Disorders / Q000209:etiology / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D009135:Muscular Diseases / Q000150:complications / Q000473:pathology* / Q000601:surgery; D010609:Pharyngeal Muscles / Q000473:pathology* / Q000601:surgery; D012507:Sarcoidosis / Q000150:complications / Q000473:pathology* / Q000601:surgery; D016896:Treatment Outcome