title: Incidence of lower limb amputations in individuals with and without diabetes mellitus in Andalusia (Spain) from 1998 to 2006.
abstract: OBJECTIVE
  We studied the changes in the incidence of lower limb amputation (LLA) in Andalusia from 1998 to 2006 in the population with and without diabetes.
  
  
  METHODS
  We undertook a retrospective study of all LLA performed in Andalusia in people aged 30 years old, with or without diabetes, between 1 January 1998 and 31 December 2006. We obtained the crude and standardized incidence rates by year, and sex for three periods: 1998-2000, 2001-2003 and 2004-2006 and calculated the RR of requiring LLA in patients with diabetes. To test for time trend, Poisson regression models were fitted.
  
  
  RESULTS
  A total of 16,210 LLA were carried out in Andalusia, 72.6% in patients with diabetes mellitus and 66.4% in men. In the population with diabetes the standardized incidence of all LLA was found to be 344.0 per 100,000 (95% CI, 315.4-372.4) in 2004-2006. There was an estimated incidence increase for all LLA by 14% and for minor LLA by 13.6% in 2004-2006. In people with diabetes the RR increased by 31.6% as compared to the first period.
  
  
  CONCLUSIONS
  Despite the implementation of a care plan for patients with diabetes, the incidence of LLA has not fallen in Andalusia in recent years.
authors: Diabetic Foot Unit, Carlos Haya University Hospital, Malaga, Spain. malmaraza@hotmail.com
authors: Maria Cruz
authors: MC
authors: Almaraz
authors: Stella
authors: S
authors: González-Romero
authors: Manuel
authors: M
authors: Bravo
authors: Félix Francisco
authors: FF
authors: Caballero
authors: Maria José
authors: MJ
authors: Palomo
authors: Rosario
authors: R
authors: Vallejo
authors: Isabel
authors: I
authors: Esteva
authors: Fernando
authors: F
authors: Calleja
authors: Federico
authors: F
authors: Soriguer
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000671:Amputation, Surgical / Q000706:statistics & numerical data* / Q000639:trends; D016022:Case-Control Studies; D003920:Diabetes Mellitus / Q000453:epidemiology / Q000601:surgery*; D005121:Extremities / Q000601:surgery*; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013030:Spain / Q000453:epidemiology