title: Synthesis of 3,5-diaryl substituted indole derivatives and its selective iodide ion chemosensing.
abstract: In this contribution, we have synthesized series of 1-ethyl-3,5-bis[2-(aryl)ethenyl]-1H-indole based derivatives with different functional groups using Wadsworth-Emmons coupling. The sensing ability of the receptors has been studied for halides like tetrabutylammonium fluoride, chloride, bromide, iodide and bisulphate by UV-vis spectroscopy methods. In THF solution, compound A-E exhibits excellent selectivity with iodide ions over the other ions like tetrabutylammonium bromide (TBABr), tetrabutylammonium chloride (TBACl), tetrabutylammonium fluoride (TBAF) and tetrabutylammonium bisulphate (TBAHSO(4)). The indole cores were observed effectively and selectively recognized biologically important iodide was reported. Significant absorption change was observed only for tetrabutylammonium iodide and no change with other anions. The absorption spectra indicated the formation of complex between host and guest is in 1:1 stoichiometric ratio. The association constants of A-E for iodide ions were found to be 3.2 × 10(4) M(-1), 3.9 × 10(4) M(-1), 4.2 × 10(3) M(-1), 2.9 × 10(3) M(-1) and 2.14 × 10(3) M(-1), respectively.
authors: Department of Chemistry, SRM University, Chennai 600026, Tamil Nadu, India.
authors: Krishnaswamy R
authors: KR
authors: Rathikrishnan
authors: Vellore K
authors: VK
authors: Indirapriyadharshini
authors: Seeram
authors: S
authors: Ramakrishna
authors: Rajendiran
authors: R
authors: Murugan
mesh_terms: D000042:Absorption / Q000528:radiation effects; D000097:Acetonitriles / Q000737:chemistry; D000838:Anions; D002625:Chemistry, Organic / Q000379:methods*; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry*; D007454:Iodides / Q000737:chemistry*; D007477:Ions; D008027:Light; D000644:Quaternary Ammonium Compounds / Q000737:chemistry; D012996:Solutions; D013056:Spectrophotometry, Ultraviolet; D017186:Titrimetry
chemical_list: D000097:Acetonitriles; D000838:Anions; D007211:Indoles; D007454:Iodides; D007477:Ions; D000644:Quaternary Ammonium Compounds; D012996:Solutions; C030374:indole; C009405:tetrabutylammonium; C032159:acetonitrile