title: Effects of a porphyrazine derivative on some developmental characteristics of Drosophila melanogaster.
abstract: In this study, the effects of a porphyrazine derivative, [octakis (2-trimethylammoniumethyl thio) porphyrazinatocobalt] octaiodide (CoPzq), were explored on the developmental characteristics, sex ratio and egg fertility of Drosophila melanogaster. CoPzq was preferred in the study due to its probability to be used as a chemotherapeutic agent in medicine. As a result of the application of CoPzq, a phenotypic abnormality was revealed within the individuals of F1 and F2 generation of Drosophila. Although individuals of F2 generation did not directly come into contact with the chemical, the rate of abnormality is high. An increase was observed within both generations in terms of the egg fertility. Besides, a deviation emerged in the sex-ratio in some concentrations.
authors: Kocaeli University, Faculty of Education, Turkey. karatasayla@gmail.com
authors: Ayla
authors: A
authors: Karatas
authors: Fatma
authors: F
authors: Ertan
authors: Neslihan
authors: N
authors: Saki
authors: Ensar
authors: E
authors: Baspınar
authors: A M
authors: AM
authors: Sevim
authors: A
authors: A
authors: Gül
mesh_terms: D000818:Animals; D019256:Cadmium Chloride / Q000633:toxicity; D004331:Drosophila melanogaster / Q000187:drug effects* / Q000254:growth & development*; D008665:Metalloporphyrins / Q000633:toxicity*; D010063:Ovum / Q000187:drug effects; D012098:Reproduction / Q000187:drug effects; D012744:Sex Ratio
chemical_list: C569268:(octakis(2-trimethylammoniumethylthio)porphyrazinatocobalt)octaiodide; D008665:Metalloporphyrins; D019256:Cadmium Chloride