title: Effect of percutaneous mitral vavuloplasty on pregnant mother and foetus--a tertiary care hospital experience from a developing country.
abstract: This study evaluated the short and long-term consequences of Percutaneous Mitral Valvuloplasty (PMV) in pregnant patients and their offspring, in a tertiary care setting, Karachi, Pakistan. The hospital database was used to retrieve all patients who underwent PMV during pregnancy in the period 1998-2007. The follow up data of the patients and the born children were obtained from the hospital records and also by contacting the patients via phone. Six patients underwent PMV but follow-up was available for 5 patients only. All 5 patients were admitted due to severe mitral stenosis with symptoms of dyspnea and palpitation. Mean age was 27 +/- 5.3 years with a mean gestational age at the time of procedure of 22.20 +/- 1.6 weeks. The mean valve area increased from 0.94 +/- 0.22 cm2 preoperatively to 1.62 +/- 0.50 cm2 post-operatively. The ejection fraction changed from a mean of 50 +/- 11.7% to 56 +/- 2.2%. There were no maternal deaths, abortions or stillbirths. Developmental milestones were achieved at the appropriate ages in all babies. PMV appears to be a safe and effective intervention for patients with severe MS during pregnancy.
  
  
  BACKGROUND
  Mitral stenosis, Percutaneous Mitral
authors: Medical College, Aga Khan University Hospital, Karachi, Pakistan.
authors: Syed Haider
authors: SH
authors: Imam
authors: Abbas Haider
authors: AH
authors: Zaidi
authors: Sana
authors: S
authors: Shoukat
authors: Sajid Hamid
authors: SH
authors: Dhakam
mesh_terms: D000328:Adult; D002404:Catheterization; D004452:Echocardiography; D015150:Echocardiography, Doppler; D005260:Female; D005500:Follow-Up Studies; D006784:Hospitals, Teaching; D006801:Humans; D008946:Mitral Valve Stenosis / Q000000981:diagnostic imaging / Q000628:therapy*; D010154:Pakistan; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000000981:diagnostic imaging / Q000628:therapy*; D011256:Pregnancy Outcome; D013997:Time Factors; D016896:Treatment Outcome; D055815:Young Adult