title: Sorbicins A and B, new urease and serine protease inhibitory triterpenes from Sorbus cashmiriana.
abstract: Two new lupene-type triterpenes, sorbicins A and B, have been isolated from the chloroform-soluble fraction of the MeOH extract from the whole plant of Sorbus cashmiriana, and their structures were elucidated by spectroscopic techniques including 2D NMR. Both compounds displayed urease and α-chymotrypsin inhibitory potential.
authors: Department of Applied Chemistry, University of Karachi, Karachi 75270, Pakistan.
authors: Mehdi Hassan
authors: MH
authors: Kazmi
authors: Itrat
authors: I
authors: Fatima
authors: Abdul
authors: A
authors: Malik
authors: Lubna
authors: L
authors: Iqbal
authors: Mehreen
authors: M
authors: Latif
authors: Nighat
authors: N
authors: Afza
mesh_terms: D002918:Chymotrypsin / Q000037:antagonists & inhibitors; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010154:Pakistan; D015842:Serine Proteinase Inhibitors / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D031994:Sorbus / Q000737:chemistry*; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D014510:Urease / Q000037:antagonists & inhibitors*
chemical_list: D015842:Serine Proteinase Inhibitors; D014315:Triterpenes; C569348:sorbicin A; C569349:sorbicin B; D002918:Chymotrypsin; C117608:alpha-chymotrypsin; D014510:Urease