title: [A kinetic lattice model of the chain-melting phase transition in lipid membrane: its experimental calibration and physiological implications].
abstract: A kinetic lattice model of chain-melting phase transition has been developed. Its time scale has been calibrated with the acoustic relaxation spectroscopic data. The model presents a tool for the analysis and predictions of kinetic features of those physiological processes in biological membranes whose mechanism is based on the phase transition in the lipid component. It has been shown that the phase-transitional mechanism can provide a high rate of synaptic exocytosis known for the fastest synapses in the central nervous system. It was also demonstrated that this mechanism can serve as an essential factor of synaptic plasticity.
authors: D P
authors: DP
authors: Kharakoz
authors: T O
authors: TO
authors: Sizonenko
authors: M Kh
authors: MKh
authors: Galimova
mesh_terms: D000465:Algorithms; D002118:Calcium / Q000378:metabolism; D002462:Cell Membrane / Q000737:chemistry* / Q000378:metabolism; D005089:Exocytosis / Q000502:physiology; D007700:Kinetics; D008560:Membrane Fluidity / Q000502:physiology; D008563:Membrane Lipids / Q000737:chemistry*; D008962:Models, Theoretical; D009010:Monte Carlo Method; D044367:Phase Transition; D009435:Synaptic Transmission / Q000502:physiology; D013997:Time Factors
chemical_list: D008563:Membrane Lipids; D002118:Calcium