title: Integration of cell biology, pharmacological modeling and statistical analysis: part I: cell biology and PK/PD in the Oncology paradigm.
abstract: The motivation of this two-part review article is to provide a comprehensive picture of cancer, cancer drugs and the detection and treatment of cancer. In order to do so, this article integrates the cell biology and biophysics of cancer as well as the modeling of preclinical Oncology drug data and statistical analysis of Oncology clinical trials data. It also discusses novel cancer diagnostic tools and standard and potential treatment options.
authors: revathia@gmail.com
authors: Revathi
authors: R
authors: Ananthakrishnan
authors: Sandeep
authors: S
authors: Menon
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000493:pharmacokinetics* / Q000494:pharmacology / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D006801:Humans; D008954:Models, Biological; D009369:Neoplasms / Q000175:diagnosis / Q000188:drug therapy* / Q000378:metabolism
chemical_list: D000970:Antineoplastic Agents