title: Five-year follow-up after anterior iris-fixated intraocular lens implantation in phakic eyes to correct high myopia.
abstract: OBJECTIVE
  To evaluate the 5-year follow-up of safety, efficacy, predictability, stability, and complications of anterior iris-fixated phakic intraocular lens (pIOL) implantation to correct high myopia, and patients' satisfaction after implantation.
  
  
  METHODS
  Prospective, nonrandomized, and comparative (self-controlled) trial.
  
  
  METHODS
  A prospective clinical trial of 84 eyes of 43 patients with high myopia was conducted. Uncorrected visual acuity (UCVA), best spectacle-corrected visual acuity (BSCVA), refraction, endothelial cell count, intraocular pressure (IOP), anterior chamber depth, slit lamp biomicroscopy, and indirect ophthalmoscope were measured preoperatively and postoperatively.
  
  
  RESULTS
  At the 5-year follow-up, UCVA was significantly improved, with 85.7% of eyes reaching 20/25 or better. No eyes experienced a loss in BSCVA, and 71.4% gained one or more lines of their preoperative BSCVA. There was a significant reduction in spherical errors in all patients after operation. Loss of endothelial cells was observed 3 years after operation and no more loss was observed 4 years after operation in statistical analysis. No increase in IOP was observed 5 years after operation in statistical analysis. No intraoperative complications were observed in this study. However, pigment precipitates of varying intensities on the lens optic were noted in all patients 1 day after operation, and only five eyes were observed to have the pigment residual five years after operation.
  
  
  CONCLUSIONS
  At the 5-year follow-up, the implantation of the anterior iris-fixated pIOL was proved to be effective, predictable and capable of reversibility to correct high myopia in phakic eyes. It was a safety addition to the laser refractive surgery. However, longer follow-up with larger numbers of patients is still necessary to evaluate long-term complications.
authors: Department of Ophthalmology, Jinling Hospital, School of Medicine, Nanjing University, Jiangsu, China.
authors: X
authors: X
authors: Yuan
authors: H Z
authors: HZ
authors: Ping
authors: W C
authors: WC
authors: Hong
authors: D
authors: D
authors: Yin
authors: Z
authors: Z
authors: Ting
mesh_terms: D000293:Adolescent; D000328:Adult; D000867:Anterior Chamber / Q000473:pathology; D002452:Cell Count; D004728:Endothelium, Corneal / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology; D007498:Iris / Q000601:surgery*; D019654:Lens Implantation, Intraocular / Q000009:adverse effects / Q000379:methods*; D007910:Lenses, Intraocular; D008297:Male; D009216:Myopia / Q000503:physiopathology / Q000601:surgery*; D011183:Postoperative Complications; D011446:Prospective Studies; D012029:Refraction, Ocular / Q000502:physiology; D014792:Visual Acuity / Q000502:physiology; D055815:Young Adult