title: Inflammatory gout: observations over a half-century.
abstract: This is a discussion of acute gouty arthritis, seen for over 50 years of engagement. It addresses the evolution of our current understanding of the interaction between urate crystals and key cellular components of the gouty inflammatory paroxysm, with new material on pathogenesis.
authors: Department of Internal Medicine, Yale University School of Medicine, P.O. Box 208031, 300 Cedar St., New Haven, CT 06520-8031, USA. stephen.malawista@yale.edu
authors: Stephen E
authors: SE
authors: Malawista
authors: Anne Chevance
authors: AC
authors: de Boisfleury
authors: Paul H
authors: PH
authors: Naccache
mesh_terms: D000818:Animals; D015210:Arthritis, Gouty / Q000209:etiology / Q000266:history* / Q000503:physiopathology; D003460:Crystallization; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D066298:In Vitro Techniques; D058847:Inflammasomes / Q000502:physiology; D009000:Monocytes / Q000502:physiology; D009504:Neutrophils / Q000502:physiology; D012106:Research / Q000266:history; D014527:Uric Acid / Q000737:chemistry
chemical_list: D058847:Inflammasomes; D014527:Uric Acid