title: A case of trimebutine-induced anaphylaxis.
abstract: Trimebutine maleate [2-dimethylamino-2-phenylbutyl 3,4,5-trimethoxybenzoic acid] has been demonstrated to be active for relieving abdominal pain and it is widely used for patients with irritable bowel syndrome. Adverse drug reactions are mostly mild and well-tolerated. To our knowledge, only two cases of trimebutine induced hypersensitivity have been reported, and both were delayed type reactions. Here, we report the first case of trimebutine maleate-induced anaphylaxis.
authors: Department of Internal Medicine, Seoul National University College of Medicine, Korea.
authors: Suh-Young
authors: SY
authors: Lee
authors: Mi-Yeong
authors: MY
authors: Kim
authors: Sung-Yoon
authors: SY
authors: Kang
authors: Woo-Jung
authors: WJ
authors: Song
authors: Hye-Ryun
authors: HR
authors: Kang
mesh_terms: D000368:Aged; D000707:Anaphylaxis / Q000139:chemically induced* / Q000175:diagnosis / Q000188:drug therapy; D005260:Female; D005765:Gastrointestinal Agents / Q000009:adverse effects*; D006801:Humans; D014287:Trimebutine / Q000009:adverse effects*
chemical_list: D005765:Gastrointestinal Agents; D014287:Trimebutine