title: Micro-contact printing of polydiacetylene liposomes using hydrophilic stamps.
abstract: Micron-sized polydiacetylene (PDA) liposome patterns have been fabricated on titanium (Ti) substrates using a micro-contact printing (micro-CP) technique. Two types of stamps (PDMS and agarose) and inking methods ("soaking" and "dropping") are used for micro-CP, and we compare their effect on the morphology of the PDA patterns. The size and morphology of the patterned PDA liposomes are analysized by optical and fluorescence microscopies and atomic force microscopy (AFM). When the agarose stamp is inked by the "dropping" method, PDA patterns are most efficiently transferred to the Ti substrate. However, the thickness of the transferred PDA patterns is not homogeneous, with the edge of the transferred pattern being thicker than its center. In contrast, when the PDMS stamp is used for micro-CP, the center of the pattern is thicker than the edge. Red fluorescence patterns are readily obtained by heat treatment of the PDA-immobilized solid substrate. The intensity of the fluorescence of the samples is consistent with the results of optical microscopy and AFM experiments.
authors: Department of Organic and Nano Engineering and Institute of Nano Science and Technology, Hanyang University, 17 Haengdang-Dong, Seongdong-Gu, Seoul 133-791, Korea.
authors: Seongil
authors: S
authors: Yu
authors: Jong-Man
authors: JM
authors: Kim
authors: Heejoon
authors: H
authors: Ahn
mesh_terms: D004129:Dimethylpolysiloxanes / Q000737:chemistry*; D057927:Hydrophobic and Hydrophilic Interactions; D008081:Liposomes / Q000737:chemistry*; D018625:Microscopy, Atomic Force; D008856:Microscopy, Fluorescence; D036103:Nanotechnology / Q000379:methods*; D000078789:Polyacetylene Polymer; D011108:Polymers / Q000737:chemistry*; D053279:Polyynes / Q000737:chemistry*; D011327:Printing / Q000379:methods*; D012685:Sepharose
chemical_list: D004129:Dimethylpolysiloxanes; D008081:Liposomes; D000078789:Polyacetylene Polymer; D011108:Polymers; D053279:Polyynes; C082361:polydiacetylene; C013830:baysilon; D012685:Sepharose