title: Direct delivery mechanisms of morphogen dispersion.
abstract: This Presentation focuses on how morphogen signaling proteins disperse across developmental fields. Although the steady-state distributions of morphogen signaling proteins have been described well in a number of contexts, the mechanisms that generate these distributions have remained uncertain. Results presented here show that these proteins transfer from producing to target cells at points of direct contact, even when the producing and target cells are not immediate neighbors.
authors: Cardiovascular Research Institute, University of California, San Francisco, CA 94158, USA.
authors: Sougata
authors: S
authors: Roy
authors: Thomas B
authors: TB
authors: Kornberg
mesh_terms: D000818:Animals; D002450:Cell Communication / Q000502:physiology*; D004331:Drosophila melanogaster; D006801:Humans; D047908:Intracellular Signaling Peptides and Proteins / Q000378:metabolism*; D015398:Signal Transduction / Q000502:physiology*
chemical_list: D047908:Intracellular Signaling Peptides and Proteins