title: Correlation of serum oestrogen with salivary calcium in post-menopausal women with and without oral dryness feeling.
abstract: OBJECTIVE
  The aim of this study was to verify the association between salivary calcium and serum oestrogen levels with oral dryness in post-menopausal women. Also, the correlation between these variables was evaluated.
  
  
  METHODS
  A case-control study was carried out on 60 selected menopausal women with and without oral dryness feeling (30 as case and 30 as control) conducted in the Department of Oral Medicine and Radiology, Maharishi Markandeshar University, Mullana, India. Paraffin-stimulated saliva samples were obtained by expectoration. Salivary calcium concentrations were assessed colorimetrically using Arsenazo III reaction. The serum oestrogen concentration was measured using ELISA. Statistical analysis of Student's t-test and Pearson correlation was used.
  
  
  RESULTS
  There was significant difference in mean values of both salivary calcium concentration and serum oestrogen between case and control groups. The result obtained also showed that an inverse correlation was found between salivary calcium concentration and serum oestrogen levels in both the groups and in total sample size.
  
  
  CONCLUSIONS
  Oral dryness in post-menopausal women is associated with high levels of salivary calcium and low levels of serum oestrogen. The concentrations of salivary calcium and serum oestrogen are inversely correlated in post-menopausal women, regardless of the presence or absence of oral dryness.
authors: Department of Oral Medicine and Radiology, MM College of Dental Sciences and Research, Ambala, Haryana, India. drravindersohi@gmail.com
authors: Ravinder
authors: R
authors: Singh
authors: Shambulingappa
authors: S
authors: Pallagatti
authors: Soheyl
authors: S
authors: Sheikh
authors: Balwinder
authors: B
authors: Singh
authors: Gagandeep
authors: G
authors: Arora
authors: Amit
authors: A
authors: Aggarwal
mesh_terms: D000368:Aged; D001150:Arsenazo III; D002118:Calcium / Q000032:analysis*; D016022:Case-Control Studies; D003124:Colorimetry; D004396:Coloring Agents; D004797:Enzyme-Linked Immunosorbent Assay; D004967:Estrogens / Q000097:blood*; D005260:Female; D006801:Humans; D008875:Middle Aged; D017698:Postmenopause / Q000097:blood* / Q000378:metabolism; D012463:Saliva / Q000737:chemistry* / Q000378:metabolism; D012636:Secretory Rate / Q000502:physiology; D014987:Xerostomia / Q000097:blood* / Q000378:metabolism
chemical_list: D004396:Coloring Agents; D004967:Estrogens; D001150:Arsenazo III; D002118:Calcium