title: Age-dependent decline of association between obesity and hyperglycemia in men and women.
abstract: OBJECTIVE
  The purpose of this study was to determine whether age influences the association between obesity and hyperglycemia.
  
  
  METHODS
  The subjects were 57,576 Japanese male and female workers aged 35-70 years. The associations of adiposity indices, including BMI, waist circumference, and waist-to-height ratio, with risk for hyperglycemia were compared among different age groups (35-39, 40-49, 50-59, and 60-70 years) using odds ratios (ORs).
  
  
  RESULTS
  There were significant trends for the crude ORs of obese subjects versus nonobese subjects for hyperglycemia to be lower as age increased in men and women. Multivariate logistic regression analysis showed these trends of age-dependent decreases in ORs for hyperglycemia were not altered by adjustment for confounders such as smoking, alcohol drinking, and habitual exercise.
  
  
  CONCLUSIONS
  The results suggest that the association between obesity and hyperglycemia declines with age in men and women.
authors: Department of Environmental and Preventive Medicine, Hyogo College of Medicine, Nishinomiya, Hyogo, Japan. wakabaya@hyo-med.ac.jp
authors: Ichiro
authors: I
authors: Wakabayashi
authors: Takashi
authors: T
authors: Daimon
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000375:Aging / Q000502:physiology*; D044466:Asian People; D015992:Body Mass Index; D015444:Exercise; D005260:Female; D006801:Humans; D006943:Hyperglycemia / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000150:complications*; D055105:Waist Circumference