title: Gabapentin in the treatment of dementia-associated nocturnal agitation.
abstract: BACKGROUND
  Nocturnal sleep of patients suffering from various forms of dementia is often impaired by nocturnal agitation or nocturnal wandering. Anticonvulsives such as carbamazepine or valproate are reported to have some therapeutic efficacy, but there is little information about other drugs suitable for treatment of this condition.
  
  
  METHODS
  Our patient, a 77-year-old Czech woman with incipient vascular dementia, received gabapentin 400mg at bedtime for 6 months and showed convincing improvement.
  
  
  CONCLUSIONS
  Gabapentin was very effective in treating nocturnal agitation.
authors: Department of Neurology - Sleep Disorders Center, 1st Faculty of Medicine and General Teaching Hospital, Charles University, Prague, Czech Republic.
authors: Jitka
authors: J
authors: Buskova
authors: Petr
authors: P
authors: Busek
authors: Sona
authors: S
authors: Nevsimalova
mesh_terms: D000368:Aged; D000588:Amines / Q000627:therapeutic use*; D014151:Anti-Anxiety Agents / Q000627:therapeutic use*; D003509:Cyclohexanecarboxylic Acids / Q000627:therapeutic use*; D003624:Darkness; D003704:Dementia / Q000150:complications* / Q000188:drug therapy*; D005260:Female; D000077206:Gabapentin; D006801:Humans; D011595:Psychomotor Agitation / Q000150:complications* / Q000188:drug therapy*; D005680:gamma-Aminobutyric Acid / Q000627:therapeutic use*
chemical_list: D000588:Amines; D014151:Anti-Anxiety Agents; D003509:Cyclohexanecarboxylic Acids; D005680:gamma-Aminobutyric Acid; D000077206:Gabapentin