title: Menelloides C and D, new sesquiterpenoids from the Gorgonian coral Menella sp.
abstract: Two new metabolites, including a lindenane-type sesquiterpenoid, menelloide C (1), and a germacrane-type sesquiterpenoid, menelloide D (2), were isolated from a Formosan gorgonian coral identified as Menella sp. The structures of 1 and 2 were established by spectroscopic methods and 2 displayed a weak inhibitory effect on the release of elastase by human neutrophils.
authors: Institute of Marine Biotechnology, National Dong Hwa University, Pingtung 944, Taiwan.|National Museum of Marine Biology and Aquarium, Pingtung 944, Taiwan.
authors: Shih-Yao
authors: SY
authors: Kao
authors: Institute of Marine Biotechnology, National Dong Hwa University, Pingtung 944, Taiwan.|National Museum of Marine Biology and Aquarium, Pingtung 944, Taiwan.|Division of Marine Biotechnology, Asia-Pacific Ocean Research Center, National Sun Yat-sen University, Kaohsiung 804, Taiwan.
authors: Jui-Hsin
authors: JH
authors: Su
authors: Graduate Institute of Natural Products, Chang Gung University, Taoyuan 333, Taiwan.
authors: Tsong-Long
authors: 0000-0002-5780-3977
authors: TL
authors: Hwang
authors: Division of Marine Biotechnology, Asia-Pacific Ocean Research Center, National Sun Yat-sen University, Kaohsiung 804, Taiwan.|Department of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 804, Taiwan.
authors: Jyh-Horng
authors: JH
authors: Sheu
authors: Division of Marine Biotechnology, Asia-Pacific Ocean Research Center, National Sun Yat-sen University, Kaohsiung 804, Taiwan.|Department of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 804, Taiwan.
authors: Zhi-Hong
authors: 0000-0003-4411-044X
authors: ZH
authors: Wen
authors: Graduate Institute of Integrated Medicine, College of Chinese Medicine, China Medical University, Taichung 404, Taiwan.|Natural Medicinal Products Research Center and Center for Molecular Medicine, China Medical University Hospital, Taichung 404, Taiwan.
authors: Yang-Chang
authors: YC
authors: Wu
authors: Institute of Marine Biotechnology, National Dong Hwa University, Pingtung 944, Taiwan.|National Museum of Marine Biology and Aquarium, Pingtung 944, Taiwan.|Division of Marine Biotechnology, Asia-Pacific Ocean Research Center, National Sun Yat-sen University, Kaohsiung 804, Taiwan.|Department of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 804, Taiwan.|Department of Life Science and Institute of Biotechnology, National Dong Hwa University, Hualien 974, Taiwan.
authors: Ping-Jyun
authors: 0000-0002-6644-9236
authors: PJ
authors: Sung
mesh_terms: D000818:Animals; D037421:Anthozoa / Q000378:metabolism*; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D010196:Pancreatic Elastase / Q000037:antagonists & inhibitors; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: D012717:Sesquiterpenes; C571236:menelloide C; C571235:menelloide D; D010196:Pancreatic Elastase