title: Physical injuries in patients with epilepsy and their associated risk factors.
abstract: OBJECTIVE
  To determine the frequency, nature, and risk factors associated with physical injuries in patients with epilepsy.
  
  
  METHODS
  In this retrospective cohort study, patients 18years of age and older with active epilepsy for at least 1year were included. A questionnaire (including age, gender, education, type of epilepsy, seizure frequency, having aura, drug compliance, polypharmacy, comorbidity, type and place of injury) was completed from patients and healthy individuals. Statistical analyses were performed using multiple logistic regression and Chi-square tests.
  
  
  RESULTS
  264 patients with epilepsy and 289 healthy participants were studied. Among patients, 8.7% reported severe injuries and 44.3% had mild injuries. Most patients reported soft tissue injuries, followed by dental injury, burn, and head injury. Severe injuries were 2.9 times more frequent among patients having generalized tonic-clonic seizures (GTCS) compared to healthy control; this was not statistically significant (P=0.07). No patient reported having severe injuries due to SPS, myoclonic or absence seizures. Mild injuries were 10.3 times more frequent among those with GTCS compared to healthy control (P=0.001). The relative risk for having injury in patients compared to control group was 3.42 (95% confidence interval: 2.50-4.69). Injury was significantly related to having GTCSs, illiteracy, having fall with seizures, comorbidity and having uncontrolled seizures.
  
  
  CONCLUSIONS
  Physical injuries are common in patients with epilepsy; however most of these injuries are mild. Severe injuries rarely occur in patients with seizures other than GTCS.
authors: Neurosciences Research Center, Shiraz University of Medical Sciences, Shiraz, Iran. aliasadipooya@yahoo.com
authors: Ali A
authors: AA
authors: Asadi-Pooya
authors: Alireza
authors: A
authors: Nikseresht
authors: Ehsan
authors: E
authors: Yaghoubi
authors: Maromi
authors: M
authors: Nei
mesh_terms: D000328:Adult; D004827:Epilepsy / Q000150:complications*; D005260:Female; D006801:Humans; D008297:Male; D012189:Retrospective Studies; D012307:Risk Factors; D012640:Seizures / Q000150:complications*; D011795:Surveys and Questionnaires; D014947:Wounds and Injuries / Q000453:epidemiology*