title: Pulling together and pulling apart: collective cargo movement in eukaryotic cells.
abstract: To establish and maintain their internal organization, living cells must move molecules to their correct locations. Long-range intracellular movements are often driven by motor molecules moving along microtubules, similarly to trucks driving along a highway. Recent work demonstrates that some randomly dispersed cargos can generate actin filaments that form a connected network whose contraction drives collective cargo movement.
authors: Department of Cellular and Molecular Pharmacology, University of California San Fransisco, San Francisco, California 94158, USA. dyche@mullinslab.ucsf.edu
authors: Dyche
authors: D
authors: Mullins
mesh_terms: D008841:Actin Cytoskeleton / Q000378:metabolism*; D000199:Actins / Q000502:physiology*; D000818:Animals; D022162:Cytoplasmic Vesicles / Q000378:metabolism*; D005260:Female; D009865:Oocytes / Q000378:metabolism*
chemical_list: D000199:Actins