title: Normal rates of neuroradiological findings in children with high functioning autism.
abstract: Magnetic resonance imaging (MRI) has been used to analyze highly specific volumetric and morphological features of the brains of individuals with autism spectrum disorder (ASD). To date, there are few comprehensive studies examining the prevalence of neuroradiologic findings seen on routine MRI scans in children with ASD. This study examined the prevalence of neuroradiologic findings in children with high functioning ASD, and compared these rates to those in children with Attention-Deficit/Hyperactivity Disorder (ADHD) and children who are typically developing (TD). Results showed that approximately 90% of children had normal MRI scans. There was no significant effect of diagnosis on the total number of neuroradiological findings or the number of specific brain findings. Implications and future research directions are discussed.
authors: Laboratory of Neurocognitive and Imaging Research, Center for Autism and Related Disorders, Kennedy Krieger Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21211, USA. vasa@kennedykrieger.org
authors: Roma A
authors: RA
authors: Vasa
authors: Marin
authors: M
authors: Ranta
authors: Thierry A G M
authors: TA
authors: Huisman
authors: Pedro S
authors: PS
authors: Pinto
authors: Rachael M
authors: RM
authors: Tillman
authors: Stewart H
authors: SH
authors: Mostofsky
mesh_terms: D000293:Adolescent; D001921:Brain / Q000473:pathology*; D002648:Child; D002659:Child Development Disorders, Pervasive / Q000473:pathology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male