title: Clinical investigation of local implantation of gentamicin-impregnated collagen sponges in dogs.
abstract: The purpose of this study was to evaluate the effects on health and kidney function of local implantation of commercial gentamicin-impregnated collagen sponges. Four healthy dogs were submitted to local surgical implantation of collagen impregnated sponges. Follow-up with serial physical examinations and measurements of serum creatinine, urea nitrogen, and gentamicin were performed for 7 d. There were no adverse reactions, or changes in measurements of kidney function.
authors: Department of Clinical Sciences, Faculty of Veterinary Medicine, University of Montreal, 1525 rue des Vétèrinaries, St-Hyacinthe (Québec) J2C 7C6, Canada.
authors: Vincent
authors: V
authors: Delfosse
authors: Alexander
authors: A
authors: El Warrak
authors: Pierre
authors: P
authors: Clerfond
authors: Bertrand
authors: B
authors: Lussier
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000008:administration & dosage* / Q000009:adverse effects; D001170:Arthritis, Infectious / Q000188:drug therapy / Q000662:veterinary*; D002358:Cartilage, Articular / Q000187:drug effects*; D003094:Collagen; D004283:Dog Diseases / Q000188:drug therapy*; D004285:Dogs; D005260:Female; D005839:Gentamicins / Q000008:administration & dosage* / Q000009:adverse effects; D008297:Male; D011446:Prospective Studies; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D005839:Gentamicins; D003094:Collagen