title: [Therapeutic evidence for manic episode].
abstract: The therapeutic guideline for the treatment of a manic episode is as follows: Firstly, lithium is the prime recommendation. In the case of a severe manic episode, the combination of lithium and atypical antipsychotic drug is recommended. Secondly, valproate, atypical antipsychotic drugs, and carbamazepine are recommended. In the case of a severe manic episode, the combination of valproate and an atypical antipsychotic drug is recommended. Finally, the combination of mood stabilizers, or the combination of mood stabilizer and typical antipsychotic drug, and electroconvulsive therapy are recommended in refractory situations.
authors: Department of Neuropsychiatry, Oita University Faculty of Medicine.
authors: Takeshi
authors: T
authors: Terao
mesh_terms: D018692:Antimanic Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D014150:Antipsychotic Agents / Q000627:therapeutic use; D001714:Bipolar Disorder / Q000188:drug therapy*; D002220:Carbamazepine / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D017050:Episode of Care; D019317:Evidence-Based Medicine; D006801:Humans; D018020:Lithium Compounds / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D014635:Valproic Acid / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*
chemical_list: D018692:Antimanic Agents; D014150:Antipsychotic Agents; D018020:Lithium Compounds; D002220:Carbamazepine; D014635:Valproic Acid