title: The HPV vaccine impact monitoring project (HPV-IMPACT): assessing early evidence of vaccination impact on HPV-associated cervical cancer precursor lesions.
abstract: The following paper describes a collaboration between the Centers for Disease Control and Prevention and five Emerging Infections Program sites to develop a comprehensive population-based approach to monitoring human papillomavirus (HPV) vaccine impact on cervical cancer precursors and associated HPV genotypes. The process of establishing this novel monitoring system is described, and development details such as enumeration of sources for reporting cervical intraepithelial neoplasia 2/3 and adenocarcinoma in situ, approaches to case ascertainment, electronic reporting, and HPV typing are outlined. Implementation of a feasible and sustainable surveillance system for HPV-associated cervical precancers will enable evaluation of the direct impact of HPV vaccination.
authors: Division of STD Prevention, National Center for HIV, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA. shariri@cdc.gov
authors: Susan
authors: S
authors: Hariri
authors: Elizabeth R
authors: ER
authors: Unger
authors: Suzanne E
authors: SE
authors: Powell
authors: Heidi M
authors: HM
authors: Bauer
authors: Nancy M
authors: NM
authors: Bennett
authors: Karen C
authors: KC
authors: Bloch
authors: Linda M
authors: LM
authors: Niccolai
authors: Sean
authors: S
authors: Schafer
authors: Lauri E
authors: LE
authors: Markowitz
mesh_terms: D000230:Adenocarcinoma / Q000276:immunology / Q000517:prevention & control; D000293:Adolescent; D000328:Adult; D005260:Female; D005838:Genotype; D006801:Humans; D027383:Papillomaviridae / Q000276:immunology; D053918:Papillomavirus Vaccines / Q000276:immunology*; D010865:Pilot Projects; D011230:Precancerous Conditions / Q000276:immunology* / Q000517:prevention & control*; D011446:Prospective Studies; D002583:Uterine Cervical Neoplasms / Q000276:immunology* / Q000517:prevention & control* / Q000821:virology; D055815:Young Adult; D002578:Uterine Cervical Dysplasia / Q000276:immunology* / Q000517:prevention & control* / Q000821:virology
chemical_list: D053918:Papillomavirus Vaccines