title: Clinical outcomes of cerebral infarctions in neonates.
abstract: Cerebral infarctions are uncommon in neonates. However, they should be considered among causes of neonatal seizures. We describe seven neonates with cerebral infarctions. Clinical presentations, perinatal history, perinatal risk factors, cranial magnetic resonance imaging and electroencephalography findings, thrombophilic factors, and clinical outcomes were reviewed. Six patients manifested seizures, whereas one exhibited cyanosis. Six neonates manifested left middle cerebral artery infarctions, and one exhibited a borderzone infarction between the anterior cerebral and middle cerebral arteries. Electroencephalograms indicated epileptiform discharges on the left hemisphere in three neonates with left middle cerebral artery territory infarctions, and epileptiform discharges on both hemispheres in one patient. At most recent follow-up visit, five patients had achieved normal development, whereas one exhibited right hemiparesis and aphasia, and another manifested toe-in gait. These findings may help predict neurodevelopmental outcomes in neonates with cerebral infarctions.
authors: Department of Pediatrics, College of Medicine, Hallym University and Gangdong Sacred Heart Hospital, Seoul, South Korea.
authors: Yoon Young
authors: YY
authors: Yi
authors: Jun Sook
authors: JS
authors: Lee
authors: So Ick
authors: SI
authors: Jang
authors: Joon Sup
authors: JS
authors: Song
authors: Seung
authors: S
authors: Yang
authors: Sung Koo
authors: SK
authors: Kim
authors: Kyoung Ja
authors: KJ
authors: Lim
authors: Il Tae
authors: IT
authors: Hwang
mesh_terms: D002544:Cerebral Infarction / Q000378:metabolism / Q000473:pathology* / Q000503:physiopathology*; D002658:Developmental Disabilities / Q000209:etiology; D038524:Diffusion Magnetic Resonance Imaging; D004569:Electroencephalography; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D020244:Infarction, Middle Cerebral Artery / Q000209:etiology; D008279:Magnetic Resonance Imaging; D008297:Male