title: Chitotriosidase levels in patients with severe endometriosis.
abstract: OBJECTIVE
  To study the levels of chitotriosidase activity in the peritoneal fluid and the plasma of patients with severe endometriosis and control subjects.
  
  
  METHODS
  Twenty-five women with laparoscopically and histopathologically confirmed endometriosis (study group) and 27 control patients who had undergone laparoscopic surgery were included. Peritoneal fluid and peripheral blood were obtained from all the patients before the surgery. Chitotriosidase activities were measured.
  
  
  RESULTS
  Analysis of chitotriosidase activity in the peritoneal fluid of patients with endometriosis showed that there was no significant difference between endometriosis and control group, respectively (32.04 ± 64.20 vs. 15.25 ± 31.17 nmol/mL/h; p > 0.05). Analysis of chitotriosidase activity in plasma of patients with endometriosis showed significantly increased levels of chitotriosidase levels compared with the control group (74.81 ± 60.54 vs. 14.10 ± 26.17; p < 0.001), respectively.
  
  
  CONCLUSIONS
  We found that the activity of chitotriosidase in plasma was statistically higher in severe endometriosis patients than women without endometriosis.
authors: Gulhane Military Medical Faculty, Obstetrics and Gynecology Department, 06018, Etlik, Ankara, Turkey. ialanbay@gmail.com
authors: İbrahim
authors: İ
authors: Alanbay
authors: Hakan
authors: H
authors: Coksuer
authors: Cihangir Mutlu
authors: CM
authors: Ercan
authors: Mehmet
authors: M
authors: Sakinci
authors: Emre
authors: E
authors: Karaşahin
authors: Seyit Temel
authors: ST
authors: Ceyhan
authors: Yusuf
authors: Y
authors: Ustun
authors: Ismail
authors: I
authors: Kurt
authors: Necdet
authors: N
authors: Ozbilen
authors: Iskender
authors: I
authors: Baser
mesh_terms: D000328:Adult; D001202:Ascitic Fluid / Q000201:enzymology*; D004715:Endometriosis / Q000201:enzymology* / Q000473:pathology / Q000601:surgery; D005260:Female; D006596:Hexosaminidases / Q000032:analysis* / Q000097:blood*; D006801:Humans; D010535:Laparoscopy
chemical_list: D006596:Hexosaminidases; C086400:chitotriosidase