title: Role of oxidative stress in disease progression in Stage B, a pre-cursor of heart failure.
abstract: Oxidative stress represents a persistent imbalance between the production and the compensation of reactive oxygen species. Though predominantly found in advanced heart failure, the most frequent "at-risk" condition has been associated with underlying oxidative stress. It is therefore conceivable that timely detection and early intervention to reduce oxidative stress processes provide an opportunity to prevent disease progression to overt heart failure. This article reviews the current understanding of the current evidence of oxidative stress involvement in the pathophysiology of human heart failure and its potential therapeutic interventions in patients with Stage A and B heart failure.
authors: Methodist DeBakey Cardiology Associates, Smith Tower, 6550 Fannin, Suite 1901, Houston, TX 77030, USA.
authors: Arvind
authors: A
authors: Bhimaraj
authors: W H Wilson
authors: WH
authors: Tang
mesh_terms: D000818:Animals; D018450:Disease Progression; D006333:Heart Failure / Q000378:metabolism* / Q000503:physiopathology; D006801:Humans; D018384:Oxidative Stress / Q000502:physiology*; D017382:Reactive Oxygen Species / Q000378:metabolism*
chemical_list: D017382:Reactive Oxygen Species