title: Rocuronium as muscle relaxant for electroconvulsive therapy in a patient with adult-onset muscular dystrophy.
abstract: Adult-onset muscular dystrophy is an inherited myopathy characterized by a variable degree of progressive muscle weakness and degeneration. Although not usually fatal, significant muscle weakness results in an up-regulation of acetylcholine receptors on the less responsive postjunctional muscles. The resulting profound potassium release when these receptors are stimulated by the depolarizing muscle relaxant succinylcholine can result in potentially fatal cardiac arrhythmias. We report a case of electroconvulsive therapy safely administered in a 61-year-old man with adult-onset muscular dystrophy requiring muscle relaxation with rocuronium.
authors: Ethan O
authors: EO
authors: Bryson
authors: Amy S
authors: AS
authors: Aloysi
authors: Maya
authors: M
authors: Katz
authors: Dennis
authors: D
authors: Popeo
authors: Charles H
authors: CH
authors: Kellner
mesh_terms: D000732:Androstanols / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D003866:Depressive Disorder / Q000150:complications* / Q000628:therapy*; D004565:Electroconvulsive Therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D009136:Muscular Dystrophies / Q000150:complications* / Q000628:therapy*; D009467:Neuromuscular Depolarizing Agents / Q000627:therapeutic use*; D000077123:Rocuronium
chemical_list: D000732:Androstanols; D009467:Neuromuscular Depolarizing Agents; D000077123:Rocuronium