title: Morbidity of appendectomy and cholecystectomy in pregnant and nonpregnant women.
abstract: OBJECTIVE
  To use the data from the American College of Surgeons (ACS) National Surgical Quality Improvement Program to estimate major postoperative morbidity after 1) appendectomy in pregnant compared with nonpregnant women; and 2) cholecystectomy in pregnant compared with nonpregnant women.
  
  
  METHODS
  We selected a cohort of reproductive-aged women undergoing appendectomy and cholecystectomy between 2005 and 2009 from the data files of the ACS National Surgical Quality Improvement Program. Outcomes in pregnant women were compared with those in nonpregnant women. The primary outcome was composite 30-day major postoperative complications. Pregnancy-specific complications were not assessed and thus not addressed.
  
  
  RESULTS
  Pregnant and nonpregnant women had similar composite 30-day major morbidity after appendectomy (3.9% [33 of 857] compared with 3.1% [593 of 19,172], P=.212) and cholecystectomy (1.8% [eight of 436] compared with 1.8% [584 of 32,479], P=.954). Pregnant women were more likely to have preoperative systemic infections before each procedure. In logistic regression analysis, pregnancy status was not predictive of increased postoperative morbidity for appendectomy (adjusted odds ratio 1.26, 95% confidence interval 0.87-1.82).
  
  
  CONCLUSIONS
  Pregnancy does not increase the occurrence of postoperative maternal morbidity related to appendectomy and cholecystectomy.
  
  
  METHODS
  II.
authors: From the Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, and the Yale Center for Analytical Sciences and Yale University School of Public Health, New Haven, Connecticut; and Bayside Ob/Gyn, LLC, Providence, Rhode Island.
authors: Mark T
authors: MT
authors: Silvestri
authors: Christian M
authors: CM
authors: Pettker
authors: E Christine
authors: EC
authors: Brousseau
authors: Madeline A
authors: MA
authors: Dick
authors: Maria M
authors: MM
authors: Ciarleglio
authors: Elisabeth A
authors: EA
authors: Erekson
mesh_terms: D000328:Adult; D001062:Appendectomy; D002763:Cholecystectomy; D005260:Female; D006801:Humans; D008875:Middle Aged; D011183:Postoperative Complications / Q000453:epidemiology*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000601:surgery*; D012189:Retrospective Studies; D055815:Young Adult