title: Congeneric lantibiotics from ribosomal in vivo peptide synthesis with noncanonical amino acids.
abstract: Expanded repetoire: Synthetic amino acids translated into propeptides dramatically increase the chemical diversity of the two-component lantibiotic lichenicidin. This opens new routes towards novel and unique peptide antibiotic sequences, which could display features important for medical applications.
authors: Institut für Chemie, Technische Universität Berlin, 10623 Berlin, Germany.
authors: Florian
authors: F
authors: Oldach
authors: Rashed
authors: R
authors: Al Toma
authors: Anja
authors: A
authors: Kuthning
authors: Tânia
authors: T
authors: Caetano
authors: Sónia
authors: S
authors: Mendo
authors: Nediljko
authors: N
authors: Budisa
authors: Roderich D
authors: RD
authors: Süssmuth
mesh_terms: D000596:Amino Acids / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000378:metabolism*; D001407:Bacillus / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D001430:Bacteriocins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D003001:Cloning, Molecular; D004926:Escherichia coli / Q000235:genetics / Q000378:metabolism*; D015870:Gene Expression; D008958:Models, Molecular; D011499:Protein Processing, Post-Translational; D012270:Ribosomes / Q000235:genetics / Q000378:metabolism*
chemical_list: D000596:Amino Acids; D000900:Anti-Bacterial Agents; D001430:Bacteriocins; C546394:lichenicidin, Bacillus licheniformis