title: Impact of childhood obesity treatment on body composition and metabolic profile.
abstract: BACKGROUND
  Childhood obesity is associated with adverse changes in cardiometabolic risk factors. A family-oriented group program stressing a health-promoting lifestyle has been more effective than routine counselling in the treatment of obesity in school children. The aim of the present study was to compare the impact of group program and routine councelling on body composition and metabolic profile, and to evaluate the associations of changes in adiposity with levels of cardiometabolic risk factors.
  
  
  METHODS
  Seventy obese prepubertal children were randomized into family-oriented group program (15 sessions for parents and children) and routine counselling (2 appointments for children). Body mass index (BMI), body composition and different metabolic risk factors were assessed before and after the 6-month intervention.
  
  
  RESULTS
  Waist/height decreased more in the children attending the group treatment, but there were no significant differences between treatment arms in the changes of metabolic risk factors. When the arms were analyzed as combined, serum triglycerides decreased significantly if BMI standard deviation score (BMI-SDS) decreased ≥ 0.5. Serum fasting insulin decreased if BMISDS decreased ≥ 0.25.
  
  
  CONCLUSIONS
  Obesity-related metabolic risk factors reduced in prepubertal children if BMI-SDS decreased substantially. This result was not dependent on which intervention, family-oriented group program or routine counselling, was used.
authors: Departments of Pediatrics and Clinical Nutrition, Kuopio University Hospital, Kuopio, Finland.
authors: Marja
authors: M
authors: Kalavainen
authors: Pauliina
authors: P
authors: Utriainen
authors: Esko
authors: E
authors: Vanninen
authors: Matti
authors: M
authors: Korppi
authors: Outi
authors: O
authors: Nuutinen
mesh_terms: D001823:Body Composition; D015992:Body Mass Index; D002648:Child; D003376:Counseling / Q000379:methods; D005196:Family Therapy / Q000379:methods; D006293:Health Promotion / Q000379:methods; D006801:Humans; D008019:Life Style; D055442:Metabolome; D009765:Obesity / Q000178:diet therapy / Q000378:metabolism* / Q000628:therapy*; D011379:Prognosis; D011615:Psychotherapy, Group / Q000379:methods; D018570:Risk Assessment; D012307:Risk Factors; D040242:Risk Reduction Behavior; D012923:Social Class; D016896:Treatment Outcome