title: Pulmonary, rhino-orbital and cutaneous mucormycosis caused by Rhizomucor pusillus in an immunocompromised patient.
abstract: The number of patients with haematopoietic malignancies receiving chemotherapy and stem-cell transplantation has increased the incidence of severe opportunistic infections. Systemic fungal infections are of major concern in immunocompromised patients, as these infections are often fatal. We report a case of a patient with acute myeloid leukaemia who developed multiple cutaneous plaques and necrotizing infiltrates in the lungs during chemotherapy. Using real-time PCR on a wax-embedded tissue sample, Rhizomucor pusillus was identified. We provide an overview of the literature on cutaneous mucormycosis and its diagnosis by PCR.
authors: Department of Dermatology, University of Heidelberg, Heidelberg, Germany. eva.hadaschik@med.uni-heidelberg.de
authors: E
authors: E
authors: Hadaschik
authors: R
authors: R
authors: Koschny
authors: B
authors: B
authors: Willinger
authors: P
authors: P
authors: Hallscheidt
authors: A
authors: A
authors: Enk
authors: W
authors: W
authors: Hartschuh
mesh_terms: D000208:Acute Disease; D000368:Aged; D003881:Dermatomycoses / Q000382:microbiology*; D006801:Humans; D016867:Immunocompromised Host; D008172:Lung Diseases, Fungal / Q000382:microbiology*; D008297:Male; D009091:Mucormycosis / Q000382:microbiology*; D016133:Polymerase Chain Reaction; D020103:Rhizomucor / Q000302:isolation & purification*; D012852:Sinusitis / Q000382:microbiology*