title: [Recent progress in the study of reduction-sensitive drug carriers].
abstract: With rapid and efficient drug release, few side effects and excellent biodegradable properties, the reduction-sensitive carriers is not only the new hot point in the field of pharmaceutical research, but also the most promising intelligent drug carrier on clinical application. This paper reviews the latest research of reduction-sensitive drug and gene carriers, including the mechanisms of drug release and the synthesis of the reduction-sensitive conjugates, reduction-sensitive nano polymer micelles, nano vesicles, nano hollow microspheres, nano liposomes, as well as the characteristics and advantages of various kinds of carrier system. It will provide a theoretical basis for its further application.
authors: College of Materials Science and Engineering, Huaqiao University, Key Laboratory for Functional Materials of Fujian Higher Education, Xiamen 361021, China.
authors: Zhong-ke
authors: ZK
authors: Tang
authors: Xing-quan
authors: XQ
authors: Xiong
authors: Lei
authors: L
authors: Cai
authors: Yuan-hong
authors: YH
authors: Xu
mesh_terms: D004337:Drug Carriers / Q000008:administration & dosage / Q000737:chemistry*; D008823:Micelles; D008863:Microspheres; D053758:Nanoparticles; D010084:Oxidation-Reduction; D004364:Pharmaceutical Preparations / Q000008:administration & dosage / Q000737:chemistry*; D011108:Polymers / Q000737:chemistry*; D012680:Sensitivity and Specificity
chemical_list: D004337:Drug Carriers; D008823:Micelles; D004364:Pharmaceutical Preparations; D011108:Polymers