title: Biographical notes on Ancel Keys and Salim Yusuf: origins and significance of the seven countries study and the INTERHEART study.
abstract: Ancel Keys and Salim Yusuf are both pioneers in preventive cardiology. Each overcame significant obstacles to demonstrate, through large international studies, how culture and environment influence cardiovascular disease. This paper will explore the origins and outcomes of their landmark studies: the Seven Countries Study, a prospective cohort model, and the INTERHEART Study, a case-control model. Each study advanced our understanding of the interplay between lifestyle, culture, and heart disease.
authors: The Cardiovascular Specialists, Hyannis, MA, USA. cmichael.wright@gmail.com
authors: C Michael
authors: CM
authors: Wright
mesh_terms: D002318:Cardiovascular Diseases / Q000097:blood / Q000266:history* / Q000517:prevention & control; D002784:Cholesterol / Q000097:blood; D004041:Dietary Fats / Q000009:adverse effects / Q000097:blood*; D049673:History, 20th Century; D007194:India; D008019:Life Style; D015337:Multicenter Studies as Topic; D018570:Risk Assessment / Q000379:methods*; D014481:United States
chemical_list: D004041:Dietary Fats; D002784:Cholesterol