title: Comparative antibacterial efficacy of endemic satureja khuzistanica jamzad essential oil, sodium hypochlorite and chlorhexidine gluconate solutions as root canal irrigations.
abstract: BACKGROUND
  The aim of this study was to compare the antibacterial efficacy of endemic Satureja Khuzistanica Jamzad (SKJ) essential oil as root canal irrigation versus 2.5% sodium hypochlorite and 2% chlorhexidine gluconate.
  
  
  METHODS
  In current in vitro experimental study, fifty four single-rooted teeth were randomly divided into 6 groups of 9 samples: 2.5% sodium hypochlorite (NaOCl), 2% chlorhexidine gluconate (CHX), 0.31 mg/ml SKJ, 0.62 mg/ml SKJ, positive and negative controls. Each tooth was instrumented, sealed and autoclaved. Then, test groups were inoculated with E. faecalis, treated with irrigation solution and viable bacterial counts in intracanal dentin chips were determined. Utilizing SPSS 18 software, collected data were analyzed by Kruskal-Wallis one way analysis of variance (P = 0.05).
  
  
  RESULTS
  99.94 % and 99.50% reduction in bacteria load after 5 min treatment with NaOCl and CHX were detected, respectively. Similarly, 99.97% and 99.96% reduction in bacterial counts were observed after 5 min application of 0.62 mg/ml and 0.31 mg/ml SKJ essential. No significant differences were detected among the four irrigation solutions (P = 0.755).
  
  
  CONCLUSIONS
  SKJ essential oil with the minimum inhibitory concentration (MIC) of 0.31 mg/ml could be an effective antibacterial irrigation solution.
authors: Assistant Professor, Department of Drug and Food Control, School of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.
authors: Nasrin
authors: N
authors: Samadi
authors: Reyhane
authors: R
authors: Zaree
authors: Hengameh
authors: H
authors: Bakhtiar
authors: Alinazar
authors: A
authors: Salehnia
authors: Shahram
authors: S
authors: Azimi