title: New insights in endometrial carcinogenesis.
abstract: Endometrial carcinoma is the most common cancer of the female genital tract in Europe and in the United States. Despite advances in defining the biology of endometrial carcinomas, there has been poor progress in determining markers that distinguish preinvasive endometrial proliferations. The aim of this review is to highlight the most recent studies regarding the molecular markers involved in endometrial adenocarcinoma pathogenesis and carcinogenesis. We focus on studies that describe markers with potential to progress from endometrial hyperplasia to invasive disease.
authors: Sbarro Institute for Cancer Research and Molecular Medicine, Center for Biotechnology, College of Science and Technology, Temple University, PA 19122, USA.
authors: Giuseppina
authors: G
authors: D'Andrilli
authors: Alessandro
authors: A
authors: Bovicelli
authors: Marco G
authors: MG
authors: Paggi
authors: Antonio
authors: A
authors: Giordano
mesh_terms: D000230:Adenocarcinoma / Q000378:metabolism* / Q000473:pathology*; D014408:Biomarkers, Tumor / Q000378:metabolism*; D002471:Cell Transformation, Neoplastic / Q000378:metabolism* / Q000473:pathology*; D004714:Endometrial Hyperplasia / Q000473:pathology; D016889:Endometrial Neoplasms / Q000378:metabolism* / Q000473:pathology*; D005260:Female; D006801:Humans; D009361:Neoplasm Invasiveness
chemical_list: D014408:Biomarkers, Tumor