title: Copper-catalyzed intramolecular hydroalkoxylation of α-(1-hydroxy-1-alkyl- and -aryl)methylallenoates by a 5-endo mode for preparation of 2-alkyl- and 2-aryl-2,5-dihydrofurans.
abstract: Ethyl α-(1-hydroxy-1-alkyl)methylallenoates and α-(1-hydroxy-1-aryl)methylallenoates containing not only electron-donating groups but also an electron-withdrawing group on the aryl group at the α-position have been shown to undergo an efficient and selective copper-catalyzed intramolecular hydroalkoxylation to give functionalized 3-ethoxycarbonyl-2-alkyl- and -aryl-2,5-dihydrofurans in good to excellent yields through a 5-endo mode.
authors: Department of Chemistry, Kangwon National University, Chuncheon 200-701, Republic of Korea.
authors: Sanghyuck
authors: S
authors: Kim
authors: Phil Ho
authors: PH
authors: Lee
mesh_terms: D000473:Alkanes / Q000737:chemistry*; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D004583:Electrons; D005663:Furans / Q000138:chemical synthesis* / Q000737:chemistry*; D015394:Molecular Structure
chemical_list: D000473:Alkanes; D005663:Furans; D003300:Copper