title: Synthesis of novel lidocaine-releasing poly(diol-co-citrate) elastomers by using deep eutectic solvents.
abstract: Poly(octanediol-co-citrate) elastomers containing high loading of lidocaine were synthesized at temperatures below 100 °C by means of using deep eutectic mixtures of 1,8-octanediol and lidocaine. The preservation of lidocaine integrity resulted in high-capacity drug-eluting elastomers.
authors: Instituto de Ciencia de Materiales de Madrid (ICMM), Consejo Superior de Investigaciones Científicas (CSIC), Cantoblanco 28049, Madrid, Spain. conchi.serrano@icmm.csic.es
authors: M Concepción
authors: MC
authors: Serrano
authors: María C
authors: MC
authors: Gutiérrez
authors: Ricardo
authors: R
authors: Jiménez
authors: M Luisa
authors: ML
authors: Ferrer
authors: Francisco
authors: F
authors: del Monte
mesh_terms: D000779:Anesthetics, Local / Q000008:administration & dosage*; D060326:Chemistry Techniques, Synthetic; D002951:Citrates / Q000138:chemical synthesis / Q000737:chemistry*; D004337:Drug Carriers / Q000138:chemical synthesis / Q000737:chemistry*; D020724:Elastomers / Q000138:chemical synthesis / Q000737:chemistry*; D006358:Hot Temperature; D008012:Lidocaine / Q000008:administration & dosage*; D011108:Polymers / Q000138:chemical synthesis / Q000737:chemistry*; D012997:Solvents / Q000737:chemistry
chemical_list: D000779:Anesthetics, Local; D002951:Citrates; D004337:Drug Carriers; D020724:Elastomers; D011108:Polymers; D012997:Solvents; C513817:poly(1,8-octanediol citrate); D008012:Lidocaine