title: Pediatric MR elastography of hepatic fibrosis: principles, technique and early clinical experience.
abstract: Numerous pediatric conditions result in hepatic fibrosis. As treatments develop for the underlying disorders, a non-invasive assessment of liver fibrosis would be beneficial as an adjunct or possible replacement for the traditional gold standard, liver biopsy. Magnetic resonance elastography is a noninvasive imaging technique that has been used successfully in adults for identification and assessment of liver fibrosis. This review describes the basic principles of MR elastography as well as the technical aspects specific to children. Clinical pediatric applications, limitations and areas for future research are described.
authors: Department of Radiology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA. binkovitz.larry@mayo.edu
authors: Larry A
authors: LA
authors: Binkovitz
authors: Mounif
authors: M
authors: El-Youssef
authors: Kevin J
authors: KJ
authors: Glaser
authors: Meng
authors: M
authors: Yin
authors: Anna K
authors: AK
authors: Binkovitz
authors: Richard L
authors: RL
authors: Ehman
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D005260:Female; D006801:Humans; D007223:Infant; D008103:Liver Cirrhosis / Q000175:diagnosis*; D008297:Male; D010865:Pilot Projects; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity