title: Gilbert syndrome increasing unconjugated hyperbilirubinemia in a child with hereditary spherocytosis.
abstract: Hemolytic anemia usually gives rise to only a modest elevation of serum bilirubin. Unconjugated hyperbilirubinemia of an extreme degree should raise suspicion of additional factors. We describe a 10-year-old child suffering from hereditary spherocytosis, who had unusually high levels of unconjugated serum bilirubin and was diagnosed to have Gilbert syndrome on the basis of genetic analysis.
authors: Department of Pediatrics, Lady Hardinge Medical College and Kalawati Saran Children's Hospital, New Delhi, India.
authors: Dipti
authors: D
authors: Kumar
authors: Ankit
authors: A
authors: Parakh
authors: Sunita
authors: S
authors: Sharma
mesh_terms: D002648:Child; D005878:Gilbert Disease / Q000150:complications*; D014453:Glucuronosyltransferase / Q000235:genetics; D006801:Humans; D006932:Hyperbilirubinemia / Q000209:etiology*; D008297:Male; D009996:Osmotic Fragility; D013103:Spherocytosis, Hereditary / Q000150:complications*; D000099148:UGT1A1 Enzyme
chemical_list: D014453:Glucuronosyltransferase; D000099148:UGT1A1 Enzyme