title: Optic disc and choroidal metastasis from sporadic medullary thyroid carcinoma: case report and review of the literature.
abstract: BACKGROUND
  Choroidal metastasis is a very rare clinical manifestation of thyroid cancer. Herein, we report on a patient with non-familial medullary thyroid carcinoma (MTC), who presented with choroidal metastasis.
  
  
  METHODS
  A 63-year-old male patient with MTC presented with sudden loss of vision in his right eye for 1 month. The patient had a history of complete thyroidectomy and chemotherapy for disseminated MTC. Ophthalmological examination showed optic disc and choroidal metastases in the right eye and a small choroidal metastasis in the left eye. The patient was scheduled for external irradiation therapy for the ocular area but died 2 months after choroidal metastasis was diagnosed.
  
  
  CONCLUSIONS
  Choroidal metastasis must be considered in MTC patients who develop loss of vision. This is a very rare clinical situation that generally occurs in the late advanced stages of the disease and carries a poor prognosis for these patients.
authors: Department of Medical Oncology, Istanbul University, Turkey. dr_ibrahim2000@yahoo.com
authors: Ibrahim
authors: I
authors: Yildiz
authors: Fatma
authors: F
authors: Sen
authors: Samuray
authors: S
authors: Tuncer
authors: Leyla
authors: L
authors: Kilic
authors: Mert
authors: M
authors: Basaran
authors: Sevil
authors: S
authors: Bavbek
mesh_terms: D018278:Carcinoma, Neuroendocrine; D002830:Choroid Neoplasms / Q000473:pathology* / Q000556:secondary*; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D008875:Middle Aged; D019574:Optic Nerve Neoplasms / Q000473:pathology* / Q000556:secondary*; D013964:Thyroid Neoplasms / Q000473:pathology*