title: Effect of carboxylic acid on micelles of a neutral amphiphilic dendro-calix[4]arene.
abstract: An amphiphilic calix[4]arene bearing branched 3,4,5-tris(2-(2-(2-methoxyethoxy)ethoxy)ethoxy)benzamide groups at the upper rim was synthesized and could increase the solubility of naproxen and ibuprofen in water through hydrogen bonding and π-π stacking interactions. The interactions between amphiphilic calix[4]arene and carboxylic acids such as naproxen and ibuprofen could reverse the direction of the branched substituents and change the shape and size of calixarene micelles from solid to hollow or linear ones.
authors: Department of Chemistry, Huazhong University of Science and Technology, Wuhan, China.
authors: Hong
authors: H
authors: Huang
authors: Dong-Mi
authors: DM
authors: Li
authors: Weizhou
authors: W
authors: Wang
authors: Yi-Chang
authors: YC
authors: Chen
authors: Khalid
authors: K
authors: Khan
authors: Song
authors: S
authors: Song
authors: Yan-Song
authors: YS
authors: Zheng
mesh_terms: D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000737:chemistry; D047250:Calixarenes / Q000737:chemistry*; D002264:Carboxylic Acids / Q000737:chemistry*; D006860:Hydrogen Bonding; D007052:Ibuprofen / Q000737:chemistry; D008823:Micelles; D009288:Naproxen / Q000737:chemistry; D010636:Phenols / Q000737:chemistry*; D012995:Solubility; D013501:Surface-Active Agents / Q000737:chemistry*; D014867:Water / Q000737:chemistry
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D002264:Carboxylic Acids; D008823:Micelles; D010636:Phenols; D013501:Surface-Active Agents; C121325:calix(4)arene; D014867:Water; D047250:Calixarenes; D009288:Naproxen; D007052:Ibuprofen