title: Solid tumor cytogenetics: current perspectives.
abstract: Conventional cytogenetics in conjunction with Fluorescence in Situ Hybridization (FISH) continues to remain an important and integral component in the diagnosis and management of solid tumors. The ability to effectively detect the vast majority of clinically relevant chromosomal aberrations with a rapid-to-acceptable turnaround time makes them the most cost-effective screening/detection tool currently available in modern pathology. In this review, we describe a representative set of solid tumors in which chromosomal analysis and/or FISH plays a significant role in the routine clinical management of solid tumors.
authors: Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California Los Angeles, 2-226 Rehab Center, 1000 Veteran Avenue, Los Angeles, CA 90024, USA.
authors: Gouri
authors: G
authors: Nanjangud
authors: Ina
authors: I
authors: Amarillo
authors: P Nagesh
authors: PN
authors: Rao
mesh_terms: D002869:Chromosome Aberrations; D003582:Cytogenetics / Q000379:methods*; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D009369:Neoplasms / Q000235:genetics*; D011379:Prognosis