title: Ethyl glucuronide.
abstract: Alcohol is associated with significant morbidity and mortality. Subjects abusing alcohol can be identified through clinical history, examination or self-report questionnaires. A range of biomarkers is available for detecting alcohol misuse, but there is still a need for a marker that can detect alcohol consumption in the time window between one day (ethanol) and one week (gamma-glutamyl transpeptidase and carbohydrate-deficient transferrin). Ethyl glucuronide is a direct metabolite that can be detected in urine for up to 90 h and has the potential to become a useful marker of 'binge' drinking. As a non-invasive marker, it could have a role in a variety of clinical and forensic settings.
authors: Department of Clinical Biochemistry, University Hospital Lewisham, High Street, Lewisham, London SE13 6LH.
authors: Natalie E
authors: NE
authors: Walsham
authors: Roy A
authors: RA
authors: Sherwood
mesh_terms: D015415:Biomarkers / Q000652:urine*; D002853:Chromatography, Liquid; D005965:Glucuronates / Q000652:urine*; D006801:Humans; D053719:Tandem Mass Spectrometry
chemical_list: D015415:Biomarkers; D005965:Glucuronates; C093924:ethyl glucuronide