title: Concurrent mycetoma and chromomycosis.
abstract: Chromoblastomycosis and Madura foot are chronic localised mycotic infection of the skin and subcutaneous tissue that follows the implantation of the fungi through minor trauma, mainly found in persons working outdoors on bare foot. In cases where both Madura and chromoblastomycosis are present, the treatment becomes difficult with low cure rates and frequent relapses. Here, we present such a very rare case of a 38-year-old cattle farmer who presented with verrucose nodules, tumefaction and multiple discharging nodules on the left lower 1/3 rd leg and foot since last 9 years. Direct KOH mount of the verrucose tissue showed Fonsecaea pedrosoi sclerotic muriform bodies and a biopsy of one granule discharging nodule demonstrated fungal mycetoma. He was put on tab. Itraconazole 200 mg o.d. and cotrimoxazole bid for 6 months with very little improvement. The rarity of this combination is most probably due to different geographical distribution.
authors: Department of Microbiology, Chhattisgarh Institute of Medical Sciences, Bilaspur, Chhattisgarh, India.
authors: R
authors: R
authors: Murthy
authors: J P
authors: JP
authors: Swain
mesh_terms: D000328:Adult; D000383:Agriculture; D000935:Antifungal Agents / Q000008:administration & dosage; D001706:Biopsy; D002862:Chromoblastomycosis / Q000150:complications* / Q000175:diagnosis* / Q000382:microbiology; D003881:Dermatomycoses / Q000382:microbiology* / Q000473:pathology*; D005658:Fungi / Q000145:classification / Q000302:isolation & purification; D006651:Histocytochemistry; D006801:Humans; D017964:Itraconazole / Q000008:administration & dosage; D007866:Leg / Q000473:pathology*; D008297:Male; D008271:Mycetoma / Q000150:complications* / Q000175:diagnosis* / Q000382:microbiology; D016896:Treatment Outcome; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000008:administration & dosage
chemical_list: D000935:Antifungal Agents; D017964:Itraconazole; D015662:Trimethoprim, Sulfamethoxazole Drug Combination