title: Troponin T in hip fracture patients: prognostic significance for mortality at one year.
abstract: Hip fractures are common injuries in the elderly, with significant mortality and morbidity from several factors. Many of these patients have cardiac disease, and some develop cardiac complications which may increase mortality. Troponin T is a marker of myocardial injury but can be raised in other conditions. Patients over 60 years admitted with hip fracture during the study period had their troponin T measured on admission and postoperatively. Assay was performed after the patient had completed their treatment. We report the results of this study one year after the last patient was admitted. 108 patients were recruited. The average age was 84 years, 86% were female. The mean hospital stay was 20 days. This study found that 27% of hip fracture patients had some increase in the troponin T levels in the peri-operative period. This increase was not associated with an increase in early mortality, but there was an increase in one-year mortality for those with an increase in troponin T (45% versus 22%, p=0.03). These findings indicate that the routine measurement of troponin T does not correlate with acute mortality and is not necessary without evidence of an acute cardiac event.
authors: Department of Orthopaedics, Peterborough City Hospital, Peterborough, UK. edward@edspurrier.co.uk
authors: Edward
authors: E
authors: Spurrier
authors: David
authors: D
authors: Wordsworth
authors: Steven
authors: S
authors: Martin
authors: Rory
authors: R
authors: Norris
authors: Martyn J
authors: MJ
authors: Parker
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D015897:Comorbidity; D005260:Female; D006331:Heart Diseases / Q000097:blood* / Q000175:diagnosis / Q000401:mortality; D006620:Hip Fractures / Q000097:blood* / Q000175:diagnosis / Q000401:mortality; D006801:Humans; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D011379:Prognosis; D015996:Survival Rate; D020107:Troponin T / Q000097:blood*; D006113:United Kingdom / Q000453:epidemiology
chemical_list: D020107:Troponin T