title: A novel technology to screen for cognitive impairment in the elderly.
abstract: BACKGROUND
  Traditional evaluation of mild cognitive impairment (MCI) can be costly, time consuming, and impractical for widespread screening. DETECT is a portable device developed to rapidly perform cognitive testing in diverse settings. This study compares DETECT with formal clinical assessment.
  
  
  METHODS
  A prospective cross-sectional comparison of the DETECT device versus an expert neuropsychologist's assessment (NPA). A total of 405 participants ≥65 years old, recruited from geriatric clinics and retirement facilities, completed both DETECT and NPA. Multivariable logistic regression methods were used to evaluate the degree of correlation between DETECT testing and the NPA diagnosis.
  
  
  RESULTS
  Predictive modeling demonstrated very good ability to discriminate between normal, MCI, and dementia per the NPA reference standard using DETECT subtests (c = 0.85 for any impairment; c = 0.99 for dementia).
  
  
  CONCLUSIONS
  DETECT scores closely correlate with NPA. DETECT can identify and discriminate between normal, MCI, and dementia and could be incorporated as a screener for MCI.
authors: Emory University School of Medicine, Department of Emergency Medicine, Atlanta, GA 30303, USA. david.wright@emory.edu
authors: David W
authors: DW
authors: Wright
authors: Harriet
authors: H
authors: Nevárez
authors: Patrick
authors: P
authors: Kilgo
authors: Michelle
authors: M
authors: LaPlaca
authors: Amber
authors: A
authors: Robinson
authors: Shawn
authors: S
authors: Fowler
authors: John
authors: J
authors: Brumfield
authors: Felicia C
authors: FC
authors: Goldstein
mesh_terms: D000368:Aged; D000544:Alzheimer Disease / Q000175:diagnosis*; D001288:Attention; D003072:Cognition Disorders / Q000175:diagnosis*; D003430:Cross-Sectional Studies; D003936:Diagnosis, Computer-Assisted / Q000295:instrumentation / Q000379:methods*; D003937:Diagnosis, Differential; D042241:Early Diagnosis; D056344:Executive Function; D006801:Humans; D016015:Logistic Models; D008403:Mass Screening / Q000295:instrumentation / Q000379:methods*; D008568:Memory; D015999:Multivariate Analysis; D009483:Neuropsychological Tests; D011237:Predictive Value of Tests; D011446:Prospective Studies; D014706:Verbal Learning