title: Regioselective synthesis and structural elucidation of 1,4-disubstituted 1,2,3-triazole derivatives using 1D and 2D NMR spectral techniques.
abstract: Regioselective synthesis of 2-[1-(2-oxo-2-phenylethyl)-1H-[1,2,3]triazol-4-ylmethoxy]-benzaldehyde derivatives was achieved by [3 + 2] cycloaddition reaction of 2-(prop)-2-ynyloxy-benzaldehyde derivatives with phenacyl azide. The regiochemistry and the spectral assignments of the synthesized triazole derivatives were studied using both 1D and 2D NMR spectral techniques in solution.
authors: Thelagathoti Hari
authors: TH
authors: Babu
authors: B V N Phani
authors: BV
authors: Kumar
authors: C
authors: C
authors: Rajeswari
authors: Paramasivan T
authors: PT
authors: Perumal
mesh_terms: D001386:Azides / Q000737:chemistry*; D001547:Benzaldehydes / Q000737:chemistry*; D060326:Chemistry Techniques, Synthetic; D002850:Chromatography, Gel; D003500:Cyclization; D013058:Mass Spectrometry; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular / Q000379:methods*; D013055:Spectrophotometry, Infrared; D013237:Stereoisomerism; D014230:Triazoles / Q000138:chemical synthesis*
chemical_list: D001386:Azides; D001547:Benzaldehydes; D014230:Triazoles