title: Emergence of five kinds of aminoglycoside-modifying enzyme genes simultaneously in a strain of multidrug-resistant Escherichia coli in China.
abstract: A strain of Escherichia coli was positive for 5 aminoglycoside modifying enzyme genes (aac(3)-I, aac(6')-Ib-cr, ant(3″″)-I, aadA5, and aph(3')-I) in PCR assays. And these positive genes confer resistance to aminoglycosides (gentamicin and tobramycin). This is the first report of emergence of five kinds of aminoglycoside-modifying enzymes genes simultaneously in E. coli worldwide.
authors: Department of Medical Laboratory, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
authors: Z
authors: Z
authors: Wang-Sheng
authors: M
authors: M
authors: Zu-Huang
authors: W
authors: W
authors: Xing-Bei
mesh_terms: D000617:Aminoglycosides / Q000494:pharmacology*; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D002681:China; D004269:DNA, Bacterial / Q000235:genetics; D024901:Drug Resistance, Multiple, Bacterial / Q000235:genetics*; D004926:Escherichia coli / Q000187:drug effects* / Q000201:enzymology* / Q000235:genetics; D008826:Microbial Sensitivity Tests
chemical_list: D000617:Aminoglycosides; D000900:Anti-Bacterial Agents; D004269:DNA, Bacterial