title: Assessment of liver transplant donor biopsies for steatosis using frozen section: accuracy and possible impact on transplantation.
abstract: BACKGROUND
  Pre-transplant frozen section evaluation for macrovesicular steatosis has long been used as a guide for donor liver utility, but may not agree with the permanent section evaluation. This study sought to evaluate the accuracy of frozen section in an active transplant service.
  
  
  METHODS
  Retrospective review of cases where frozen section analysis was undertaken to assess percent macrovesicular steatosis was performed, comparing the frozen section diagnosis to the final diagnosis.
  
  
  RESULTS
  Ninety-six cases were available for review. In 7 of these cases (7%), the difference between the two slides was significant; that is, the difference between the two slides may have contributed to a change in clinical management at a cutoff of 30%.
  
  
  CONCLUSIONS
  Clinicians need to be aware that accuracy is satisfactory in experienced hands but some discrepancies may occur.
  
  
  BACKGROUND
  Liver; Steatosis; Pathology.
authors: New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, New Jersey, USA.
authors: Benjamin
authors: B
authors: Heller
authors: Stephen
authors: S
authors: Peters