title: A screening for essential cell growth-related genes involved in arsenite toxicity in Saccharomyces cerevisiae.
abstract: Genes that are essential for growth in yeast were screened to identify those involved in arsenite sensitivity. We found that the knockdown of YPT1, ERG8, or RKI1 enhanced arsenite sensitivity  in yeast.
authors: Laboratory of Molecular and Biochemical Toxicology, Graduate School of Pharmaceutical Sciences,Tohoku University, Sendai, Miyagi, Japan.
authors: Tsutomu
authors: T
authors: Takahashi
authors: Shohei
authors: S
authors: Satake
authors: Ken-ichiro
authors: K
authors: Hirose
authors: Gi-Wook
authors: GW
authors: Hwang
authors: Akira
authors: A
authors: Naganuma
mesh_terms: D019747:Aldose-Ketose Isomerases / Q000235:genetics; D018053:Arsenites / Q000633:toxicity*; D015966:Gene Expression Regulation, Fungal; D055785:Gene Knockdown Techniques; D020043:Genes, Essential / Q000235:genetics; D005800:Genes, Fungal / Q000235:genetics*; D017856:Phosphotransferases (Phosphate Group Acceptor) / Q000235:genetics; D060888:Real-Time Polymerase Chain Reaction; D012441:Saccharomyces cerevisiae / Q000235:genetics* / Q000254:growth & development*; D029701:Saccharomyces cerevisiae Proteins / Q000235:genetics; D020691:rab GTP-Binding Proteins / Q000235:genetics
chemical_list: D018053:Arsenites; D029701:Saccharomyces cerevisiae Proteins; D017856:Phosphotransferases (Phosphate Group Acceptor); C022371:phosphomevalonate kinase; C060755:YPT1 protein, S cerevisiae; D020691:rab GTP-Binding Proteins; D019747:Aldose-Ketose Isomerases; C487718:RKI1 protein, S cerevisiae; C015001:arsenite