title: [Plasma renin and aldosterone levels in obese and non-obese women with polycystic ovary syndrome].
abstract: OBJECTIVE
  To assess plasma renin and aldosterone levels in obese and non-obese women with polycystic ovary syndrome (PCOS).
  
  
  METHODS
  Obese women (body mass index [BMI]>30 kg/m2; group A, n=34) and non-obese women (BMI<25 kg/m2; group B, n=13) with PCOS were selected. The control group (groupC, n =47) consisted of age-matched women with regular menses and normal ultrasonographic ovaries. Luteinizing hormone, follicle-stimulating hormone, androstenedione, testosterone, sex hormone-binding globulin, serum glucose, insulin, renin, plasma renin activity, and aldosterone levels were measured.
  
  
  RESULTS
  Obese and non-obese women with PCOS had higher luteinizing hormone, follicle-stimulating hormone, androstenedione, testosterone, and insulin levels as compared to women in the control group (p<0.05). Women with PCOS had significantly higher renin levels (group A: 50.2±4.9 picoU/mL, group B: 39.9±2.7 picoU/mL, and group C: 24.6±2.6 picoU/mL), plasma renin activity (group A: 3.7±0.3 ng/mL/h, group B: 3.6±0.3 ng/mL/h, and group C: 2.2±0.4 ng/mL/h), and aldosterone levels (group A: 31.2±3.3 ng/dL, group B: 29.3±2.9 ng/dL, and group C: 22.2±3.9 ng/dL) as compared with controls.
  
  
  CONCLUSIONS
  Significant differences exist in plasma renin and aldosterone levels between obese and non-obese women as compared with polycystic ovary syndrome and normal controls.
authors: Servicio de Ginecología, Hospital Central Dr. Urquinaona, Maracaibo, Estado Zulia, Venezuela.
authors: Jorly
authors: J
authors: Mejia-Montilla
authors: Eduardo
authors: E
authors: Reyna-Villasmil
authors: Duly
authors: D
authors: Torres-Cepeda
authors: Joel
authors: J
authors: Santos-Bolívar
authors: Nadia
authors: N
authors: Reyna-Villasmil
authors: Alfonso
authors: A
authors: Bravo-Henríquez
mesh_terms: D000328:Adult; D000450:Aldosterone / Q000097:blood*; D001786:Blood Glucose / Q000032:analysis; D015992:Body Mass Index; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood; D012739:Gonadal Steroid Hormones / Q000097:blood; D006801:Humans; D007328:Insulin / Q000097:blood; D007986:Luteinizing Hormone / Q000097:blood; D008954:Models, Biological; D009765:Obesity / Q000097:blood* / Q000150:complications; D011085:Polycystic Ovary Syndrome / Q000097:blood* / Q000150:complications / Q000000981:diagnostic imaging; D012083:Renin / Q000097:blood*; D012738:Sex Hormone-Binding Globulin / Q000032:analysis; D014463:Ultrasonography; D049629:Waist-Hip Ratio; D055815:Young Adult
chemical_list: D001786:Blood Glucose; D012739:Gonadal Steroid Hormones; D007328:Insulin; D012738:Sex Hormone-Binding Globulin; D000450:Aldosterone; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone; D012083:Renin