title: Assessment of risk factors for early seizures following surgery for meningiomas using logistic regression analysis.
abstract: This study analysed the influence of clinical factors on early postoperative seizures in patients with meningiomas and constructed a logistic regression equation for assessing risk factors. Clinical data from 222 patients with meningiomas were collected. The odds ratios (ORs) for independent  variables were determined: the ORs for preoperative seizure history and movement disorder were > 1, whereas the OR for prophylactic therapy was < 1. A logistic regression analysis was then performed to select potential risk factors for early postoperative seizures. Five variables (preoperative  seizure history, movement disorder, tumour location, primary location of initial tumour and prophylactic therapy) were introduced into the regression model. A logistic regression equation was then constructed that had a positive predictive value of 66.65% and a negative predictive value of  84.95%. This suggested that the five variables introduced in the equation were closely associated with early postoperative seizures, with preoperative seizure history and movement disorder as potential risk factors and prophylactic therapy as a protective factor.
authors: Department of Neurosurgery, First Hospital of Jilin University, Changchun, China.
authors: B
authors: B
authors: Zhang
authors: G
authors: G
authors: Zhao
authors: H-F
authors: HF
authors: Yang
authors: D
authors: D
authors: Wang
authors: J-L
authors: JL
authors: Yu
authors: H-Y
authors: HY
authors: Huang
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D008577:Meningeal Neoplasms / Q000601:surgery*; D008579:Meningioma / Q000601:surgery*; D008875:Middle Aged; D016017:Odds Ratio; D011183:Postoperative Complications / Q000209:etiology*; D012189:Retrospective Studies; D012307:Risk Factors; D012640:Seizures / Q000209:etiology*; D055815:Young Adult