title: The impact of the dibutyrylchitin molar mass on the bioactive properties of dressings used to treat soft tissue wounds.
abstract: In this work, we describe a novel technique for producing biocompatible medical products with bioactive properties from the biodegradable polymer dibutyrylchitin (DBC). Materials produced by blowing out polymer solutions have excellent hemostaic properties and are easy to handle during surgery. Biocompatibility studies, encompassing hemostasis and the evaluation of post-implantation reactions, indicate that the biological properties of DBC depend on the molecular mass of the polymer. Lower molecular mass polymers are preferable for use in implanted wound dressings.
authors: Department of Material and Commodity Sciences and Textile Metrology, Technical University of Lodz, Lodz, Poland. izabella.krucinska@p.lodz.pl
authors: Izabella
authors: I
authors: Krucinska
authors: Agnieszka
authors: A
authors: Komisarczyk
authors: Danuta
authors: D
authors: Paluch
authors: Maria
authors: M
authors: Szymonowicz
authors: Boguslawa
authors: B
authors: Zywicka
authors: Stanislaw
authors: S
authors: Pielka
mesh_terms: D020341:Absorbable Implants; D000818:Animals; D001684:Biological Dressings; D002686:Chitin / Q000031:analogs & derivatives*; D006488:Hemostasis, Surgical / Q000379:methods; D006490:Hemostatics; D006801:Humans; D008297:Male; D008422:Materials Testing / Q000379:methods*; D051381:Rats; D017208:Rats, Wistar; D014947:Wounds and Injuries / Q000628:therapy*
chemical_list: D006490:Hemostatics; C528051:di-O-butyrylchitin; D002686:Chitin