title: Cruciferous vegetables intake and risk of prostate cancer: a meta-analysis.
abstract: OBJECTIVE
  To evaluate the relationship between cruciferous vegetables intake and risk of prostate cancer.
  
  
  METHODS
  A systematic literature search up to June 2011 was carried out in PubMed, and the references of retrieved articles were screened. The summary relative risks with 95% confidence interval for the highest versus the lowest intake of cruciferous vegetables were calculated. Heterogeneity and publication bias were also evaluated.
  
  
  RESULTS
  Seven cohort and six population-based case-control studies met the inclusion criteria of the meta-analysis. A significantly decreased prostate cancer risk was observed overall in the cruciferous vegetables intake group (relative risks = 0.90; 95% confidence interval 0.85-0.96) and the subgroup of case-control studies (relative risks = 0.79; 95% confidence interval 0.69-0.89), but not in cohort studies (relative risks = 0.95; 95% confidence interval 0.88-1.02). No heterogeneity and publication bias were detected across studies.
  
  
  CONCLUSIONS
  Cruciferous vegetables intake is related to the decreased risk of prostate cancer. Because of the limited number of studies, further prospective studies are needed to explore the protective effect of cruciferous vegetables on prostate cancer.
authors: Department of Urology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.
authors: Ben
authors: B
authors: Liu
authors: Qiqi
authors: Q
authors: Mao
authors: Min
authors: M
authors: Cao
authors: Liping
authors: L
authors: Xie
mesh_terms: D019607:Brassicaceae; D005247:Feeding Behavior; D014943:Global Health; D006801:Humans; D015994:Incidence; D008297:Male; D011471:Prostatic Neoplasms / Q000453:epidemiology / Q000517:prevention & control*; D018570:Risk Assessment; D011795:Surveys and Questionnaires; D014675:Vegetables