title: Recent advances in curdlan biosynthesis, biotechnological production, and applications.
abstract: Curdlan is a water-insoluble β-(1,3)-glucan produced by Agrobacterium species under nitrogen-limited condition. Its heat-induced gelling properties render curdlan to be very useful in the food industry initially. Recent advances in the understanding of the role curdlan plays in both innate and adaptive immunity lead to its growing applications in biomedicine. Our review focuses on the recent advances on curdlan biosynthesis and the improvements of curdlan fermentation production both from our laboratory and many others as well as the latest advances on the new applications of curdlan and its derivatives particularly in their immunological functions in biomedicine.
authors: Key Laboratory of Carbohydrate Chemistry and Biotechnology of Ministry of Education, School of Biotechnology, Jiangnan University, 1800, Lihu Road, Wuxi, 214122, China. xbzhan@yahoo.com
authors: Xiao-Bei
authors: XB
authors: Zhan
authors: Chi-Chung
authors: CC
authors: Lin
authors: Hong-Tao
authors: HT
authors: Zhang
mesh_terms: D060054:Agrobacterium / Q000378:metabolism*; D001688:Biological Products / Q000302:isolation & purification* / Q000378:metabolism* / Q000494:pharmacology; D001709:Biotechnology / Q000379:methods*; D007155:Immunologic Factors / Q000302:isolation & purification / Q000378:metabolism / Q000494:pharmacology; D047071:beta-Glucans / Q000302:isolation & purification* / Q000378:metabolism* / Q000494:pharmacology
chemical_list: D001688:Biological Products; D007155:Immunologic Factors; D047071:beta-Glucans; C038459:curdlan