title: A computer-assisted model for detection of MRI signs of Crohn's disease activity: future or fiction?
abstract: Magnetic resonance imaging is increasingly used for abdominal evaluation and is more and more considered as the optimal imaging technique for detection of mural inflammation in patients with Crohn's disease. Grading the disease activity is important in daily clinical practice to monitor the medical treatment and is assessed by evaluating different magnetic resonance imaging features. Unfortunately, only moderate interobserver agreement is reported for most of the subjective features and should be improved. A computer-assisted model for automatic detection of abnormalities, ability to grade disease severity, and thereby influence clinical disease management based on magnetic resonance imaging is missing. Recent techniques have focused on semi-automated methods for classification and segmentation of the bowel and also on objective measurement of bowel wall enhancement using absolute T1-values or dynamic contrast-enhanced imaging. This article reviews the available computerized techniques, as well as preferred developments.
authors: Department of Radiology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands. j.a.w.tielbeek@amc.uva.nl
authors: Jeroen A W
authors: JA
authors: Tielbeek
authors: Frans M
authors: FM
authors: Vos
authors: Jaap
authors: J
authors: Stoker
mesh_terms: D003424:Crohn Disease / Q000473:pathology*; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods* / Q000592:standards; D007421:Intestine, Small / Q000473:pathology; D008279:Magnetic Resonance Imaging / Q000379:methods*; D012720:Severity of Illness Index