title: Relapse of minimal change disease following infection with the 2009 pandemic influenza (H1N1) virus.
abstract: We report a case of relapse of minimal change disease following infection with the influenza A (H1N1) virus responsible for the 2009 pandemic. A 22-year-old man who had been diagnosed with minimal change disease presented with systemic edema. He had achieved complete remission with an oral steroid (prednisolone 1 mg/kg/day) by the 17th day of administration. On the 27th day of prednisolone administration, he presented with a new onset of generalized edema after several days of productive coughing. His urine showed proteinuria (4+) with a protein/creatinine ratio (PCR) of 2852.1 mg/g. His nasal swab sample was positive for the 2009 pandemic influenza (H1N1) virus by real-time reverse-transcriptase polymerase chain reaction (RT-PCR). He received oseltamivir (150 mg/day) for 5 days. A day after completing the oseltamivir therapy, his proteinuria returned to a normal range; urinalysis was negative for protein with PCR 79.2 mg/g. One month later, the patient remained normal with no proteinuria.
authors: Division of Nephrology, Department of Internal Medicine,  Pusan National University School of Medicine, Beomeo-ri, Mulgeum-eup, Yangsan, Gyeongsangnam-do, 626-770, South Korea.
authors: Seo Rin
authors: SR
authors: Kim
authors: Soo Bong
authors: SB
authors: Lee
authors: Il Young
authors: IY
authors: Kim
authors: Dong Won
authors: DW
authors: Lee
authors: Harin
authors: H
authors: Rhee
authors: Eun Young
authors: EY
authors: Seong
authors: Sang Heon
authors: SH
authors: Song
authors: Ihm Soo
authors: IS
authors: Kwak
mesh_terms: D000998:Antiviral Agents / Q000627:therapeutic use*; D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype; D007251:Influenza, Human / Q000150:complications* / Q000188:drug therapy; D007668:Kidney / Q000473:pathology; D008297:Male; D009402:Nephrosis, Lipoid / Q000473:pathology / Q000821:virology*; D053139:Oseltamivir / Q000627:therapeutic use*; D058873:Pandemics; D012008:Recurrence; D055815:Young Adult
chemical_list: D000998:Antiviral Agents; D053139:Oseltamivir