title: Value of the modified Hodge test for detection of emerging carbapenemases in Enterobacteriaceae.
abstract: The modified Hodge test has an excellent sensitivity for detecting enterobacterial isolates producing Ambler class A (KPC) and class D (OXA-48) carbapenemases. Its sensitivity is low for NDM-1 producers (50%) but is increased to 85.7% by adding ZnSO(4) (100 μg/ml) in the culture medium. However, this test has a low specificity and is time-consuming.
authors: Service de Bactériologie-Virologie, INSERM U914 Emerging Resistance to Antibiotics, Hôpital de Bicêtre, Assistance Publique/Hôpitaux de Paris, Faculté de Médecine Paris Sud, K.-Bicêtre, France.
authors: Delphine
authors: D
authors: Girlich
authors: Laurent
authors: L
authors: Poirel
authors: Patrice
authors: P
authors: Nordmann
mesh_terms: D001426:Bacterial Proteins / Q000032:analysis*; D001431:Bacteriological Techniques / Q000379:methods*; D003470:Culture Media / Q000737:chemistry; D004755:Enterobacteriaceae / Q000201:enzymology*; D012680:Sensitivity and Specificity; D019287:Zinc Sulfate / Q000378:metabolism; D001618:beta-Lactamases / Q000032:analysis*
chemical_list: D001426:Bacterial Proteins; D003470:Culture Media; D019287:Zinc Sulfate; D001618:beta-Lactamases; C063912:carbapenemase