title: Can intraluminal devices prevent or reduce colorectal anastomotic leakage: a review.
abstract: Colorectal anastomotic leakage is a serious complication of colorectal surgery, leading to high morbidity and mortality rates. In recent decades, many strategies aimed at lowering the incidence of anastomotic leakage have been examined. The focus of this review will be on mechanical aids protecting the colonic anastomosis against leakage. A literature search was performed using MEDLINE, EMBASE, and The Cochrane Collaborative library for all papers related to prevention of anastomotic leakage by placement of a device in the colon. Devices were categorised as decompression devices, intracolonic devices, and biodegradable devices. A decompression device functions by keeping the anal sphincter open, thereby lowering the intraluminal pressure and lowering the pressure on the anastomosis. Intracolonic devices do not prevent the formation of dehiscence. However, they prevent the faecal load from contacting the anastomotic site, thereby preventing leakage of faeces into the peritoneal cavity. Many attempts have been made to find a device that decreases the incidence of AL; however, to date, none of the devices have been widely accepted.
authors: Division of Abdominal Surgery, Department of Surgery, University Medical Center Groningen, 9700 RB Groningen, The Netherlands.
authors: Annelien N
authors: AN
authors: Morks
authors: Klaas
authors: K
authors: Havenga
authors: Rutger J
authors: RJ
authors: Ploeg
mesh_terms: D000714:Anastomosis, Surgical / Q000009:adverse effects* / Q000295:instrumentation* / Q000379:methods; D057868:Anastomotic Leak / Q000517:prevention & control*; D000818:Animals; D002986:Clinical Trials as Topic; D003106:Colon / Q000601:surgery*; D003107:Colorectal Surgery / Q000009:adverse effects* / Q000295:instrumentation* / Q000379:methods; D016208:Databases, Factual; D006801:Humans; D011183:Postoperative Complications / Q000517:prevention & control*; D012189:Retrospective Studies