title: [Use of sugammadex in a patient with narrow angle glaucoma].
abstract: An 86-year-old woman was scheduled to receive fourth reconstructive surgery for femoral bone fracture under general anesthesia. She had been suspected with narrow angle glaucoma due to headache and bloodshot eyes during gastroscopy. During transfer to our hospital, she fell down and suffered from the right femoral neck fracture. The patient underwent femoral head replacement under spinal anesthesia. Later, she received surgeries twice uneventfully under spinal anesthesia; removal and re-implantation of the femoral bone head due to infection of the implanted head. Six months later, she fell down again and femoral bone was fractured during rehabilitation. Anesthesia was induced with propofol followed by rocuronium 0.9 mg x kg(-1) i.v. Anesthesia was maintained with propofol and remifentanil, and rocuronium was administered to maintain PTC of 10 or less. The surgery was completed in 150 minutes. At the end of surgery, a laryngeal mask was inserted and the tracheal tube was removed. TOF ratio recovered to 80% 8 minutes after sugammadex 2 mg kg(-1) i.v., and increased to 100% 3 minutes after additional 1 mg x kg(-1). Intraocular pressure stayed below 20 mmHg during the intervention. We could achieve full reversal of neuromuscular blockade and suppress increase in intraocular pressure with use of sugammadex.
authors: Department of Anesthesiology, Kansai Medical University, Takii Hospital, Moriguchi 570-8507.
authors: Michiko
authors: M
authors: Yamamoto
authors: Kohei
authors: K
authors: Murao
authors: Michiyo
authors: M
authors: Kimoto
authors: Shoko
authors: S
authors: Inoue
authors: Tomoko
authors: T
authors: Kanouda
authors: Kumiko
authors: K
authors: Nakamura
authors: Koh
authors: K
authors: Shingu
mesh_terms: D000369:Aged, 80 and over; D000732:Androstanols / Q000037:antagonists & inhibitors; D000775:Anesthesia, Spinal; D019644:Arthroplasty, Replacement, Hip; D005260:Female; D005265:Femoral Neck Fractures / Q000150:complications / Q000601:surgery; D015812:Glaucoma, Angle-Closure / Q000150:complications*; D006801:Humans; D017214:Laryngeal Masks; D000077123:Rocuronium; D000077122:Sugammadex; D047408:gamma-Cyclodextrins / Q000008:administration & dosage* / Q000494:pharmacology
chemical_list: D000732:Androstanols; D047408:gamma-Cyclodextrins; D000077122:Sugammadex; D000077123:Rocuronium