title: Effect of kidney transplantation on heart conduction disturbances in children treated with chronic hemodialysis--a pilot study.
abstract: Aim of the study was to assess the effect of KT on heart conduction in HD children. Non-invasive electrocardiographic method of BSPM was used. Isochrone maps, presenting a VAT distribution, were taken from eight HD patients and 26 normal subjects. Patients were divided into two groups: I--three children were HD <12 months prior to KT; II--five children were HD >12 months prior to KT. After KT, the groups were marked as IP and IIP. Serum iPTH and phosphate levels were significantly higher in both HD groups than in controls, with a considerable normalization after transplantation. HD patients demonstrated neither conduction abnormalities on ECG nor left ventricular hypertrophy. Group-mean VAT maps revealed: I and II--similar patterns of complete LBBB; IP--partial normalization to a pattern of anterior fascicle block; IIP--preserved pattern of LBBB. Intraventricular conduction disturbances found in HD children using BSPM were alleviated by KT. Short HD therapy increases a chance of conduction disturbances regression after KT, contrary to the longer HD treatment. BSPM is more sensitive than standard ECG in detecting heart conduction impairments in the HD patients.
authors: Department of Pediatric Nephrology, Wroclaw Medical University, Wrocław, Poland. dpjonkisz@nefped.am.wroc.pl
authors: Dorota
authors: D
authors: Polak-Jonkisz
authors: Krystyna
authors: K
authors: Laszki-Szcząchor
authors: Małgorzata
authors: M
authors: Sobieszczańska
authors: Irena
authors: I
authors: Makulska
authors: Witold
authors: W
authors: Pilecki
authors: Lesław
authors: L
authors: Rusiecki
authors: Danuta
authors: D
authors: Zwolińska
mesh_terms: D000293:Adolescent; D001145:Arrhythmias, Cardiac / Q000175:diagnosis / Q000209:etiology*; D018780:Body Surface Potential Mapping; D002037:Bundle-Branch Block / Q000175:diagnosis / Q000209:etiology; D002648:Child; D004562:Electrocardiography; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000601:surgery / Q000628:therapy*; D016030:Kidney Transplantation; D008297:Male; D006435:Renal Dialysis / Q000009:adverse effects*