title: Regiospecific functionalization of azacalixaromatics through copper-mediated aryl C-H activation and C-O bond formation.
abstract: Regiospecific functionalization of tetraazacalix[1]arene[3]pyridines at the lower rim position of the benzene ring was achieved conveniently from their cross-coupling reaction with both aliphatic alcohols including chiral primary and secondary alcohols and phenol derivatives through the Cu(ClO(4))(2)-mediated aerobic aryl C-H activation, which gave structurally well-defined aryl-Cu(III) intermediates and a subsequent C-O bond formation reaction under very mild conditions.
authors: Key Laboratory for Organic Phosphorus Chemistry and Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University, Beijing 100084, China.
authors: Zu-Li
authors: ZL
authors: Wang
authors: Liang
authors: L
authors: Zhao
authors: Mei-Xiang
authors: MX
authors: Wang