title: HIV infection and bone disease: implications for an aging population.
abstract: Now more than ever, the management of age-related problems, from cardiovascular morbidity to bone pathology, is increasingly relevant for HIV physicians. Low bone mineral density (BMD) and fractures are more common in HIV-infected patients. Although a multifactorial aetiology underlies this condition, increasing evidence suggests a role for antiretroviral therapy in low BMD, especially upon initiation. This review will detail the epidemiology, pathogenesis, diagnosis and management of osteoporosis and low BMD in HIV-infected patients, with particular emphasis on aging.
authors: HIV Molecular Research Group, School of Medicine & Medical Science, University College Dublin 7, Ireland. Aoife.cotter@ucdconnect.ie
authors: Aoife G
authors: AG
authors: Cotter
authors: Patrick W G
authors: PW
authors: Mallon
mesh_terms: D000368:Aged; D000375:Aging; D019380:Anti-HIV Agents / Q000627:therapeutic use; D023241:Antiretroviral Therapy, Highly Active; D015519:Bone Density / Q000187:drug effects; D050071:Bone Density Conservation Agents / Q000627:therapeutic use; D001847:Bone Diseases / Q000188:drug therapy* / Q000453:epidemiology* / Q000821:virology; D015897:Comorbidity; D015658:HIV Infections / Q000188:drug therapy* / Q000453:epidemiology*; D006801:Humans; D008017:Life Expectancy; D012307:Risk Factors
chemical_list: D019380:Anti-HIV Agents; D050071:Bone Density Conservation Agents