title: [Risk and benefit of oral anticoagulants in atrial fibrillation].
abstract: Thromboembolism is the main cause of death and disability of patients with atrial fibrillation. Indirect anticoagulants are effective means of primary and secondary prevention of thromboembolic complications. However in a number of patients risk associated with therapy with indirect anticoagulants might exceed potential benefit. The principle problem requiring solution in a patient with atrial fibrillation is individual comparative assessment of risk of development of thromboembolic and hemorrhagic complications. Modern stratification scales which allow solving this problem are considered in this review.
authors: I V
authors: IV
authors: Zotova
authors: D A
authors: DA
authors: Zateĭshchikov
mesh_terms: D000284:Administration, Oral; D000925:Anticoagulants / Q000008:administration & dosage / Q000009:adverse effects; D001281:Atrial Fibrillation / Q000150:complications / Q000188:drug therapy*; D001777:Blood Coagulation / Q000187:drug effects*; D006470:Hemorrhage / Q000139:chemically induced / Q000453:epidemiology / Q000517:prevention & control; D006801:Humans; D020766:Intracranial Embolism / Q000209:etiology / Q000517:prevention & control; D016015:Logistic Models; D008991:Monitoring, Physiologic / Q000592:standards / Q000706:statistics & numerical data; D018570:Risk Assessment; D012307:Risk Factors; D055502:Secondary Prevention; D014894:Weights and Measures / Q000592:standards*
chemical_list: D000925:Anticoagulants