title: Synthesis and antihyperlipidemic activity of acetylated derivative of ulvan from Ulva pertusa.
abstract: In this study, acetylated ulvan (AU) was prepared with acetic anhydride in N,N-dimethylacetamide, and the antihyperlipidemic activity of natural ulvan and its acetylated ulvan derivative (AU) in mice was determined. Obvious differences in antihyperlipidemic activity between natural ulvan and its derivative were observed, moreover, AU showed stronger antihyperlipidemic activity on triglyceride (TG) and low density lipoprotein cholesterol (LDL-C).
authors: Weifang Medical University, Weifang, PR China.
authors: Huimin
authors: H
authors: Qi
authors: Xiaolei
authors: X
authors: Liu
authors: Jinbao
authors: J
authors: Zhang
authors: Yu
authors: Y
authors: Duan
authors: Xiaolan
authors: X
authors: Wang
authors: Quanbin
authors: Q
authors: Zhang
mesh_terms: D000107:Acetylation; D000818:Animals; D002784:Cholesterol / Q000737:chemistry; D008078:Cholesterol, LDL / Q000737:chemistry*; D005260:Female; D006949:Hyperlipidemias / Q000188:drug therapy*; D008297:Male; D051379:Mice; D015233:Models, Statistical; D009539:Nicotinic Acids / Q000737:chemistry; D010936:Plant Extracts / Q000494:pharmacology; D011134:Polysaccharides / Q000737:chemistry / Q000378:metabolism* / Q000494:pharmacology; D013696:Temperature; D014280:Triglycerides / Q000737:chemistry*; D044445:Ulva / Q000378:metabolism*
chemical_list: D008078:Cholesterol, LDL; D009539:Nicotinic Acids; D010936:Plant Extracts; D011134:Polysaccharides; D014280:Triglycerides; C571831:ulvan; D002784:Cholesterol; C005193:Inositol Niacinate