title: Is Ceftriaxone-Induced Biliary Pseudolithiasis Influenced by UDP-Glucuronosyltransferase 1A1 Gene Polymorphisms?
abstract: Ceftriaxone (cfx), a third-generation cephalosporin antibiotic, leads to transient cholelithiasis in some children, also known as pseudolithiasis. However, the underlying pathogenetic mechanism of this adverse effect has not yet been elucidated. We describe 3 children with ceftriaxone-induced pseudolithiasis, who were also carriers of the A(TA)(7)TAA polymorphism of the UGT1A1 gene, implying that a cause and effect relation may exist.
authors: Third Department of Pediatrics, "Attikon" General University Hospital, 1 Rimini Street, Haidari, 124 62 Athens, Greece.
authors: Andrew
authors: A
authors: Fretzayas
authors: Olga
authors: O
authors: Liapi
authors: Anna
authors: A
authors: Papadopoulou
authors: Polyxeni
authors: P
authors: Nicolaidou
authors: Alexandra
authors: A
authors: Stamoulakatou