title: Effects of depression and anxiety symptoms on cardiac mortality following myocardial infarction: a 2-year follow-up.
abstract: OBJECTIVE
  The purpose of this study was to determine the impact of symptoms of depression and anxiety on mortality in patients hospitalized for acute myocardial infarction (MI).
  
  
  METHODS
  A total of 806 consecutive patients were screened within 15 days after MI and 24-month survival rate was ascertained. The Beck Depression Inventory and the State-Trait Anxiety Inventory were completed by patients hospitalized for MI. We tested the BDI × STAI interaction effect in addition to the BDI and STAI main effects.
  
  
  RESULTS
  At 24 months' follow up cardiac mortality was assessed in 540 of 806 eligible patients (67% response rate); 531 of 806 for whom baseline data were collected (65.9%) were depressed and 556 (69.0%) were anxious after their MI. Fifty-five (10.2%) patients died during the 24-month follow-up. Neither state of anxiety nor depression scores at entry was different between patients who died from those who survived.
  
  
  CONCLUSIONS
  Symptoms of depression and anxiety did not predict cardiac mortality after MI, but despite the negative results regarding the impact of depression on cardiac outcome, it should be stressed that this does not mean that physicians and cardiologists could ignore depression and anxiety.
authors: Psychiatry and Science Behavior Research Center, Department of Psychiatry, Mazandaran University of Medical Sciences, Sari, Iran. swt_f@yahoo.com
authors: Seyed Hamzeh
authors: SH
authors: Hosseini
authors: Keyvan
authors: K
authors: Yousefnejad
authors: Sasan
authors: S
authors: Tabiban
authors: Vida
authors: V
authors: Nesarhoseyni
authors: Babak
authors: B
authors: Bagheri
authors: Asadolah Mohseni
authors: AM
authors: Kiasari
authors: Ali
authors: A
authors: Ghaemian
authors: Seyed Naser
authors: SN
authors: Ghadirnejad
authors: Hamideh Azimi
authors: HA
authors: Lolati
authors: Fatemeh Nasiri
authors: FN
authors: Amiri
authors: Haleh
authors: H
authors: Ashraf
authors: Vahid
authors: V
authors: Mokhberi
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001007:Anxiety / Q000150:complications / Q000401:mortality*; D001008:Anxiety Disorders / Q000150:complications / Q000401:mortality*; D003863:Depression / Q000150:complications / Q000401:mortality*; D003866:Depressive Disorder / Q000150:complications / Q000401:mortality*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007492:Iran / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000150:complications / Q000401:mortality*; D012307:Risk Factors; D015996:Survival Rate