title: Incidences of cancers in diabetic and non-diabetic hospitalized adult patients in Taiwan.
abstract: BACKGROUND
  The study was to investigate the relationship between diabetes mellitus ( DM), specific cancers, age, and gender.
  
  
  METHODS
  This was a retrospective study that examined the frequency of different forms of cancer among male and female patients with or without DM admitted to a single hospital in Taiwan between January 2009 and June 2010.
  
  
  RESULTS
  Of 101,002 study patients admitted to the hospital, 15,901 (15.74%) were diagnosed with DM and 16,748 (16.58%) with a malignancy. The frequency of DM differed between males and females (17.5% vs 14.2%; P<0.001), and males had a higher cancer incidence than females (20.2% vs 13.5%; P<0.001). Patients with DM had a greater frequency of cancer diagnosis than non-DM patients (18.1% vs 16.3%, respectively), with pancreatic, liver, uterine, urinary tract, lung, and secondary cancers being more frequent in DM compared with non-DM patients. In contrast, the proportion of patients with thyroid, esophagus, breast, NPC, and other cancers was lower in DM versus non-DM patients.
  
  
  CONCLUSIONS
  This study found that DM was associated with the incidence of specific cancers and that males had a higher frequency of cancer than females. The association of DM and cancer depended upon cancer type, gender, and age.
authors: Department of Industrial Design, Healthy Aging Research Center, Chang Gung University, and Department of Internal Medicine, Chang Gung Memorial Hospital, Taoyuan Hsien, Taiwan.
authors: Wen-Ko
authors: WK
authors: Chiou
authors: Bie-Yu
authors: BY
authors: Huang
authors: Wei-Ying
authors: WY
authors: Chou
authors: Hsiao-Fen
authors: HF
authors: Weng
authors: Jen-Der
authors: JD
authors: Lin
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D048909:Diabetes Complications; D003920:Diabetes Mellitus / Q000453:epidemiology*; D005260:Female; D006760:Hospitalization; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000150:complications / Q000453:epidemiology*; D012189:Retrospective Studies; D012307:Risk Factors; D012737:Sex Factors; D013624:Taiwan / Q000453:epidemiology; D055815:Young Adult