title: αβ T cell receptors come out swinging.
abstract: It is unclear how an effective T cell repertoire is built from a limited array of T cell receptor (TCR) genes. In this issue of Immunity, Stadinski et al. (2011) demonstrate that TCR variable (V) α chains can indirectly affect Vβ-mediated recognition of the major histocompatibility complex (MHC) molecule.
authors: Department of Microbiology and Immunology, The University of Melbourne, Parkville, Victoria, 3010, Australia. sjturn@unimelb.edu.au
authors: Stephen J
authors: SJ
authors: Turner
authors: Jamie
authors: J
authors: Rossjohn