title: Interpenetrating polymer networks of poly(N-vinylacetamide) and stimuli responsive polymers applied to novel amphiphilic gel.
abstract: The swelling behaviors of IPN with poly(N-vinylacetamide) (PNVA), which possibly converts from nonionic gel to cationic gel, and the stimuli responsive polymers, such as poly(acrylic acid) (PAAc) and poly(N-isopropylacrylamide) (PNIPAm) were investigated in order to prepare the stimuli responsive amphiphilic gel. When the monomer concentrations were uniformed at the IPN preparation, the obtained PNVA/PAAc IPN showed the pH responsivity with around 100 of swelling ratio at pH 4 to around 1 of swelling ratio at pH 2, although it lost the amphiphilicity due to the lack of swelling in ethanol. On the other hand, the gelation of N-vinylacetamide at 2 M in PNIPAM gel resulted in thermosensitive and amphiphilic hydrogel, that the swelling ratio in EtOH/water (3/7, v/v) also decreased, compared to the value in water at 25 degrees C.
authors: The Center for Advanced Medical Engineering and Informatics, Osaka University, 2-2, Yamada-oka, Suita, Osaka 565-0871, Japan.
authors: Hiroharu
authors: H
authors: Ajiro
authors: Yukie
authors: Y
authors: Takemoto
authors: Mitsuru
authors: M
authors: Akashi
mesh_terms: D000081:Acetamides / Q000737:chemistry*; D005782:Gels; D006863:Hydrogen-Ion Concentration; D011108:Polymers / Q000737:chemistry*; D011145:Polyvinyls / Q000737:chemistry*
chemical_list: D000081:Acetamides; D005782:Gels; D011108:Polymers; D011145:Polyvinyls; C539745:poly(N-vinylacetamide)