title: Sexual dimorphism of sulcal length asymmetry in the cerebrum of adult cynomolgus monkeys (Macaca fascicularis).
abstract: The present study aimed to quantitatively clarify the gross anatomical asymmetry and sexual dimorphism of the cerebral hemispheres of cynomolgus monkeys. While the fronto-occipital length of the right and left cerebral hemispheres was not different between sexes, a statistically significant rightward asymmetry was detected in the cerebral width at the perisylvian region in females, but not in males (narrower width of the left side in the females). An asymmetry quotient of the sulcal lengths revealed a rightward asymmetry in the inferior occipital sulcus and a leftward asymmetry in the central and intraparietal sulci in both sexes. However, the laterality of the lengths of other sulci was different for males and females. The arcuate sulcus was directed rightward in males but there was no rightward bias in females. Interestingly, the principle sulcus and lateral fissure were left-lateralized in the males, but right-lateralized in the females. The results suggest that lateralization patterns are regionally and sexually different in the cerebrum of cynomolgus monkeys. The present results provide a reference for quantitatively evaluating the normality of the cerebral cortical morphology in cynomolgus monkeys.
authors: Department of Anatomy and Developmental Neurobiology, University of Tokushima Graduate School Institute of Health Biosciences.
authors: Noritaka
authors: N
authors: Imai
authors: Kazuhiko
authors: K
authors: Sawada
authors: Katsuhiro
authors: K
authors: Fukunishi
authors: Hiromi
authors: H
authors: Sakata-Haga
authors: Yoshihiro
authors: Y
authors: Fukui
mesh_terms: D000818:Animals; D001931:Brain Mapping / Q000379:methods; D054022:Cerebrum / Q000033:anatomy & histology*; D005260:Female; D005625:Frontal Lobe / Q000033:anatomy & histology; D008252:Macaca fascicularis / Q000033:anatomy & histology*; D008297:Male; D012727:Sex Characteristics