title: Therapeutic consequences of crystals in the synovial fluid: a review for clinicians.
abstract: Many crystals may be found in arthritic joints. Rheumatologists are able to diagnose, with a high degree of probability, which crystals induce arthritis in the individual case. A definite diagnosis supported by polarisation microscopy may provide a firm basis for adequate long-term treatment. Recently new insights in the inflammatory processes induced the development of targeted therapies. We review novel developments in crystal-induced arthritis and gout in particular.
authors: Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands. t.jansen@reuma.umcn.nl
authors: Tim L
authors: TL
authors: Jansen
authors: Johannes J
authors: JJ
authors: Rasker
mesh_terms: D001168:Arthritis / Q000175:diagnosis* / Q000378:metabolism; D002131:Calcium Pyrophosphate / Q000378:metabolism; D002784:Cholesterol / Q000378:metabolism; D003460:Crystallization; D006073:Gout / Q000175:diagnosis / Q000378:metabolism; D006801:Humans; D007596:Joints / Q000378:metabolism / Q000473:pathology*; D008859:Microscopy, Polarization; D013582:Synovial Fluid; D014527:Uric Acid / Q000378:metabolism
chemical_list: D014527:Uric Acid; D002784:Cholesterol; D002131:Calcium Pyrophosphate