title: Microwave-Assisted Synthesis of N-Phenylsuccinimide.
abstract: A microwave-assisted synthesis of N-phenylsuccinimide has been developed for the second-semester organic teaching laboratory. Utilizing this procedure, N-phenylsuccinimide can be synthesized by heating a mixture of aniline and succinic anhydride in a domestic microwave oven for four minutes in moderate yields (40-60%). This technique reduces the reaction time as compared to the traditional synthesis by several hours, which allows the preparation to be achieved in a single organic chemistry laboratory period. This reaction is performed in the absence of solvent, is energy efficient, and is atom economical; therefore, it represents a "greener" preparation than the traditional synthesis of N-phenylsuccinimide.
authors: Department of Chemistry, West Virginia State University, Institute, West Virginia 25112 United States.
authors: Thomas A
authors: TA
authors: Shell
authors: Jennifer R
authors: JR
authors: Shell
authors: Kathleen A
authors: KA
authors: Poole
authors: Thomas F
authors: TF
authors: Guetzloff