title: MSnbase-an R/Bioconductor package for isobaric tagged mass spectrometry data visualization, processing and quantitation.
abstract: MSnbase is an R/Bioconductor package for the analysis of quantitative proteomics experiments that use isobaric tagging. It provides an exploratory data analysis framework for reproducible research, allowing raw data import, quality control, visualization, data processing and quantitation. MSnbase allows direct integration of quantitative proteomics data with additional facilities for statistical analysis provided by the Bioconductor project.
  
  
  BACKGROUND
  MSnbase is implemented in R (version ≥ 2.13.0) and available at the Bioconductor web site (http://www.bioconductor.org/). Vignettes outlining typical workflows, input/output capabilities and detailing underlying infrastructure are included in the package.
authors: Cambridge Centre for Proteomics, Cambridge Systems Biology Centre, Department of Biochemistry, University of Cambridge, Tennis Court Road, CB2 1QR, Cambridge, UK. lg390@cam.ac.uk
authors: Laurent
authors: L
authors: Gatto
authors: Kathryn S
authors: KS
authors: Lilley
mesh_terms: D013058:Mass Spectrometry / Q000379:methods; D040901:Proteomics / Q000379:methods*; D012984:Software