title: Unusual presentation of primary gastric choriocarcinoma in a 24-year-old female patient.
abstract: We report a case of a young female patient presenting with a high serum beta-HCG levels, amenorrhea, nausea and anemia which mimicked pregnancy followed by upper gastrointestinal bleeding. A gastric tumor was shown on endoscopy. Histopathologic evaluation revealed Primary Gastric Choriocarcinoma (PGC). The patient was treated with three cycles of standard nongestational choriocarcinoma chemotherapy. Tumor persistence was evidenced by CT Scans and high serum beta-HCG levels. The patient died approximately six months after diagnosis. Our case report suggest that PGC is a highly aggressive tumor that is often associated with liver and lungs metastasis without evidence of pelvic organ abnormality and is associated with some hormonal effects, such as amenorrhea, anemia, nausea and vomiting mimicking pregnancy in young adult female
authors: Department of Internal Medicine, San Juan City Hospital, San Juan, Puerto Rico. mscasiano002@yahoo.com
authors: Mónica
authors: M
authors: Santiago Casiano
authors: Liza M
authors: LM
authors: Paulo Malavé
authors: Eduardo
authors: E
authors: Fahme
authors: Sandra N
authors: SN
authors: Maldonado Rivera
authors: Omayra
authors: O
authors: González
authors: William
authors: W
authors: Cáceres Perkins
authors: José
authors: J
authors: Hernán Martínez
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D014408:Biomarkers, Tumor / Q000097:blood; D001761:Bleomycin / Q000008:administration & dosage; D031954:Choriocarcinoma, Non-gestational / Q000175:diagnosis* / Q000188:drug therapy / Q000556:secondary; D018997:Chorionic Gonadotropin, beta Subunit, Human / Q000097:blood; D002945:Cisplatin / Q000008:administration & dosage; D003951:Diagnostic Errors; D005047:Etoposide / Q000008:administration & dosage; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007069:Ifosfamide / Q000008:administration & dosage; D008113:Liver Neoplasms / Q000556:secondary; D008175:Lung Neoplasms / Q000556:secondary; D008727:Methotrexate / Q000008:administration & dosage; D017239:Paclitaxel / Q000008:administration & dosage; D011247:Pregnancy; D011271:Pregnancy, Ectopic / Q000175:diagnosis; D016879:Salvage Therapy; D013274:Stomach Neoplasms / Q000175:diagnosis* / Q000188:drug therapy; D055815:Young Adult
chemical_list: D014408:Biomarkers, Tumor; D018997:Chorionic Gonadotropin, beta Subunit, Human; D001761:Bleomycin; D005047:Etoposide; D017239:Paclitaxel; D002945:Cisplatin; D007069:Ifosfamide; D008727:Methotrexate