title: Vascular catastrophes following pancreas transplantation: an evolution in strategy at a single center.
abstract: BACKGROUND
  Complications of pancreas transplantation involving the arterial anastomosis are potentially life threatening. In this report, we review our experience with such vascular catastrophes.
  
  
  METHODS
  Pancreas transplants performed between January 2003 and December 2009 were reviewed. All cases of pseudoaneurysm (PA) or arterioenteric fistula (AEF) were included.
  
  
  RESULTS
  Of 346 pancreas transplants, 10 vascular catastrophes in nine recipients were identified. There were five PAs, one involving the pancreas allograft, one involving the donor iliac artery Y-graft stump following allograft pancreatectomy, two involving the kidney allograft, and one involving the bifurcation of the Y-graft. The latter was treated with coil embolization, but subsequently developed into an AEF. There were five AEFs including the recipient mentioned above. Four had a failed allograft and three had discontinued immunosuppression. The final case had a clamp injury to the proximal common iliac artery that fistulized to the donor duodenum. The management, course and outcome of all nine recipients are described in detail.
  
  
  CONCLUSIONS
  Vascular catastrophes such as PA and AEF are potentially life-threatening complications of pancreas transplantation. Immediate treatment at the time of bleeding is essential and covered stenting of the involved artery may provide immediate vascular control in these situations.
authors: Department of Surgery, Indiana University School of Medicine, Indianapolis, IN 46202, USA. jfridell@iupui.edu
authors: Jonathan A
authors: JA
authors: Fridell
authors: Matthew S
authors: MS
authors: Johnson
authors: William C
authors: WC
authors: Goggins
authors: Thiago
authors: T
authors: Beduschi
authors: Muhammad A
authors: MA
authors: Mujtaba
authors: Michelle L
authors: ML
authors: Goble
authors: John A
authors: JA
authors: Powelson
mesh_terms: D000328:Adult; D017541:Aneurysm, False / Q000209:etiology*; D005260:Female; D006801:Humans; D007083:Iliac Artery; D007412:Intestinal Fistula / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D016035:Pancreas Transplantation / Q000009:adverse effects*; D011183:Postoperative Complications; D011379:Prognosis; D012189:Retrospective Studies; D055815:Young Adult