title: Nanoparticle shape improves delivery: rational coarse grain molecular dynamics (rCG-MD) of taxol in worm-like PEG-PCL micelles.
authors: Chemical and Biomolecular Engineering, University of Pennsylvania, 129 Towne Building, 220 South 33rd St., University of Pennsylvania, Philadelphia, PA 19104, USA. sloverde@seas.upenn.edu
authors: Sharon M
authors: SM
authors: Loverde
authors: Michael L
authors: ML
authors: Klein
authors: Dennis E
authors: DE
authors: Discher
mesh_terms: D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000008:administration & dosage / Q000737:chemistry; D001672:Biocompatible Materials / Q000737:chemistry; D004337:Drug Carriers / Q000737:chemistry; D005027:Ethylene Oxide / Q000737:chemistry*; D006801:Humans; D007783:Lactones / Q000737:chemistry*; D008422:Materials Testing; D008823:Micelles; D008958:Models, Molecular; D056004:Molecular Dynamics Simulation; D053758:Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure*; D036103:Nanotechnology; D017239:Paclitaxel / Q000008:administration & dosage* / Q000737:chemistry; D010316:Particle Size
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D001672:Biocompatible Materials; D004337:Drug Carriers; D007783:Lactones; D008823:Micelles; C400421:PLC(20)-b-PEO(44); D005027:Ethylene Oxide; D017239:Paclitaxel