title: Patient preferences for psoriasis treatments: process characteristics can outweigh outcome attributes.
abstract: OBJECTIVE
  To assess patients' preferences for psoriasis treatments and to identify the effect of sociodemographic and socioeconomic characteristics on these preferences.
  
  
  METHODS
  A computer-based conjoint analysis experiment was conducted to analyze the preferences of individuals with moderate or severe psoriasis for outcome attributes (probability, magnitude, and duration of benefit, as well as probability, severity, and reversibility of adverse effects) and process attributes (treatment location, frequency, duration, delivery method, and individual cost) of psoriasis treatments. Relative importance scores (RISs) for each attribute were calculated. The effect of sociodemographic (age, sex, and marital status) and socioeconomic (income and employment) characteristics and Psoriasis Area and Severity Index and Dermatology Life Quality Index scores on preferences was assessed using analysis of variance, post hoc testing, and multivariate regression analysis.
  
  
  METHODS
  Outpatient dermatology clinic at a German university medical center.
  
  
  METHODS
  Patients with moderate or severe psoriasis (N = 163).
  
  
  METHODS
  Relative importance scores for treatment attributes.
  
  
  RESULTS
  The attribute considered to be most important in patients' preferences for psoriasis treatments was treatment location (RIS, 26.76), followed by probability of benefit (RIS, 23.77) and method of delivery (RIS, 23.49). The RISs for all process attributes were higher than for adverse effect-related attributes. Older individuals (≥65 years) were less concerned about the probability of benefit (β = -0.24; P = .005) compared with younger individuals.
  
  
  CONCLUSIONS
  When choosing among treatment options, individuals with psoriasis appear to be willing to accept treatment-related adverse effects to obtain process attributes compatible with their personal and professional life. Incorporating preferences in shared decision making may facilitate treatment adherence and optimize outcome.
authors: Department of Dermatology, University Medical Centre Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68135 Mannheim, Germany.
authors: Marthe-Lisa
authors: ML
authors: Schaarschmidt
authors: Astrid
authors: A
authors: Schmieder
authors: Nasir
authors: N
authors: Umar
authors: Darcey
authors: D
authors: Terris
authors: Matthias
authors: M
authors: Goebeler
authors: Sergj
authors: S
authors: Goerdt
authors: Wiebke K
authors: WK
authors: Peitsch
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D003657:Decision Making; D005260:Female; D005858:Germany; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D017063:Outcome Assessment, Health Care / Q000379:methods*; D010349:Patient Compliance; D010358:Patient Participation; D057240:Patient Preference; D011565:Psoriasis / Q000473:pathology / Q000628:therapy*; D012044:Regression Analysis; D012720:Severity of Illness Index; D012959:Socioeconomic Factors; D012984:Software; D055815:Young Adult