title: Splenic Doppler impedance indices estimate splenic congestion in patients with right-sided or congestive heart failure.
abstract: Splenic Doppler impedance indices are measurements of splenic congestion in chronic liver disease. It is not known whether they can also assess splenic congestion in patients affected by right-sided or congestive heart failure. We analyzed splanchnic hemodynamics with Doppler ultrasound and systemic hemodynamics with right-sided heart catheterization in patients with heart failure. Splenic pulsatility index (PI) was higher in patients with heart failure (48 patients) compared with healthy subjects (39 patients) (1.19 ± 0.41 vs. 0.73 ± 0.11, p < 0.0001) and was related to hepatic vein diameter (p = 0.02). Splenic PI was not related to systemic arterial pressure, cardiac output, systemic vascular resistance or splenic arterial resistance, whereas it was related to right atrial mean pressure (p = 0.0003) and to right ventricle end-diastolic pressure (p = 0.011) (34 patients). In conclusion, splenic PI is a measurement of splenic congestion caused by an increase in venous outflow resistance. It can estimate splenic congestion in patients with right-sided or congestive heart failure.
authors: Department of Clinical and Experimental Medicine, University of Padua, Padua, Italy. massimo.bolognesi@unipd.it
authors: Massimo
authors: M
authors: Bolognesi
authors: Cristina
authors: C
authors: Quaglio
authors: Giancarlo
authors: G
authors: Bombonato
authors: Silvia
authors: S
authors: Gaiani
authors: Paola
authors: P
authors: Pesce
authors: Paola
authors: P
authors: Bizzotto
authors: Enrico
authors: E
authors: Favaretto
authors: Angelo
authors: A
authors: Gatta
authors: David
authors: D
authors: Sacerdoti
mesh_terms: D001783:Blood Flow Velocity; D017097:Electric Impedance; D005260:Female; D006333:Heart Failure / Q000150:complications / Q000000981:diagnostic imaging / Q000503:physiopathology*; D006801:Humans; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D008297:Male; D008875:Middle Aged; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013154:Spleen / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D013157:Splenic Artery / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D018608:Ultrasonography, Doppler / Q000379:methods*; D014655:Vascular Resistance