title: Anaplastic large cell lymphoma of scrotal skin.
abstract: Cutaneous T cell lymphoma (CTCL) is an uncommon diverse group of lympho-proliferative disorders involving the skin. They vary considerably in clinical presentation, microscopic features and immunophenotyping. The diagnosis is challenging, zealous, and often not easy. CD30+ve anaplastic large cell lymphoma is extremely rare. Its clinical spectrum varies from a solitary unifocal skin lesion of excellent prognosis to a multi focal systemic disease having a poor out come. The diagnosis is quite cumbersome, and often difficult. The differential diagnosis include from benign skin lesions to secondary cutaneous involvement by lymphoma. A correct diagnosis is integral with a complete metastatic/staging work up to avoid over treatment. The treatment options depend on extent of disease involvement and include surgical excision, surveillance, local radiotherapy, and systemic chemotherapy. The prognosis is good with unifocal local disease. We present here a very rare case of CD30+ ALCL of scrotal skin, in a middle aged male patient.
authors: Department of Medical Oncology, National Cancer Centre, Royal Hospital Muscat, Oman.
authors: Itrat
authors: I
authors: Mehdi
authors: Indira
authors: I
authors: Praseeda
authors: Bassim Jaffer
authors: BJ
authors: Al-Bahrani
authors: Namrata
authors: N
authors: Satayapal
authors: Assam Abdel
authors: AA
authors: Monem
authors: Suad
authors: S
authors: Al Kharusi
mesh_terms: D000964:Antimetabolites, Antineoplastic / Q000008:administration & dosage; D001706:Biopsy; D003131:Combined Modality Therapy; D006801:Humans; D017730:Ki-1 Antigen / Q000378:metabolism; D017728:Lymphoma, Large-Cell, Anaplastic / Q000473:pathology* / Q000628:therapy; D054446:Lymphoma, Primary Cutaneous Anaplastic Large Cell / Q000175:diagnosis* / Q000532:radiotherapy / Q000628:therapy; D008297:Male; D008875:Middle Aged; D009850:Oman; D011878:Radiotherapy; D012611:Scrotum; D012878:Skin Neoplasms / Q000473:pathology* / Q000532:radiotherapy / Q000628:therapy; D016896:Treatment Outcome
chemical_list: D000964:Antimetabolites, Antineoplastic; D017730:Ki-1 Antigen