title: Hyperprolactinemia and infertility.
abstract: Prolactin-secreting pituitary tumors are a common cause of amenorrhea and infertility in premenopausal women. The goals of therapy are to normalize prolactin, restore gonadal function and fertility, and reduce tumor size, and dopamine agonists are the preferred therapy. Clinically significant tumor enlargement during pregnancy is uncommon and dependent on tumor size and prepregnancy treatment.
authors: Division of Endocrinology and Metabolism, Department of Internal Medicine, University of Iowa, Iowa City, USA.
authors: Amal
authors: A
authors: Shibli-Rahhal
authors: Janet
authors: J
authors: Schlechte
mesh_terms: D018491:Dopamine Agonists / Q000009:adverse effects / Q000627:therapeutic use; D005260:Female; D047109:Fetal Development / Q000187:drug effects; D006801:Humans; D006966:Hyperprolactinemia / Q000150:complications* / Q000503:physiopathology / Q000628:therapy; D007247:Infertility, Female / Q000209:etiology*; D010911:Pituitary Neoplasms / Q000473:pathology / Q000503:physiopathology / Q000628:therapy; D011247:Pregnancy; D011248:Pregnancy Complications; D011252:Pregnancy Complications, Neoplastic; D015175:Prolactinoma / Q000473:pathology / Q000503:physiopathology / Q000628:therapy
chemical_list: D018491:Dopamine Agonists