title: The genome of Tetranychus urticae reveals herbivorous pest adaptations.
abstract: The spider mite Tetranychus urticae is a cosmopolitan agricultural pest with an extensive host plant range and an extreme record of pesticide resistance. Here we present the completely sequenced and annotated spider mite genome, representing the first complete chelicerate genome. At 90 megabases T. urticae has the smallest sequenced arthropod genome. Compared with other arthropods, the spider mite genome shows unique changes in the hormonal environment and organization of the Hox complex, and also reveals evolutionary innovation of silk production. We find strong signatures of polyphagy and detoxification in gene families associated with feeding on different hosts and in new gene families acquired by lateral gene transfer. Deep transcriptome analysis of mites feeding on different plants shows how this pest responds to a changing host environment. The T. urticae genome thus offers new insights into arthropod evolution and plant-herbivore interactions, and provides unique opportunities for developing novel plant protection strategies.
authors: Department of Biology, The University of Western Ontario, London N6A 5B7, Canada. mgrbic@uwo.ca
authors: Miodrag
authors: M
authors: Grbić
authors: Thomas
authors: T
authors: Van Leeuwen
authors: Richard M
authors: RM
authors: Clark
authors: Stephane
authors: S
authors: Rombauts
authors: Pierre
authors: P
authors: Rouzé
authors: Vojislava
authors: V
authors: Grbić
authors: Edward J
authors: EJ
authors: Osborne
authors: Wannes
authors: W
authors: Dermauw
authors: Phuong Cao Thi
authors: PC
authors: Ngoc
authors: Félix
authors: F
authors: Ortego
authors: Pedro
authors: P
authors: Hernández-Crespo
authors: Isabel
authors: I
authors: Diaz
authors: Manuel
authors: M
authors: Martinez
authors: Maria
authors: M
authors: Navajas
authors: Élio
authors: É
authors: Sucena
authors: Sara
authors: S
authors: Magalhães
authors: Lisa
authors: L
authors: Nagy
authors: Ryan M
authors: RM
authors: Pace
authors: Sergej
authors: S
authors: Djuranović
authors: Guy
authors: G
authors: Smagghe
authors: Masatoshi
authors: M
authors: Iga
authors: Olivier
authors: O
authors: Christiaens
authors: Jan A
authors: JA
authors: Veenstra
authors: John
authors: J
authors: Ewer
authors: Rodrigo Mancilla
authors: RM
authors: Villalobos
authors: Jeffrey L
authors: JL
authors: Hutter
authors: Stephen D
authors: SD
authors: Hudson
authors: Marisela
authors: M
authors: Velez
authors: Soojin V
authors: SV
authors: Yi
authors: Jia
authors: J
authors: Zeng
authors: Andre
authors: A
authors: Pires-daSilva
authors: Fernando
authors: F
authors: Roch
authors: Marc
authors: M
authors: Cazaux
authors: Marie
authors: M
authors: Navarro
authors: Vladimir
authors: V
authors: Zhurov
authors: Gustavo
authors: G
authors: Acevedo
authors: Anica
authors: A
authors: Bjelica
authors: Jeffrey A
authors: JA
authors: Fawcett
authors: Eric
authors: E
authors: Bonnet
authors: Cindy
authors: C
authors: Martens
authors: Guy
authors: G
authors: Baele
authors: Lothar
authors: L
authors: Wissler
authors: Aminael
authors: A
authors: Sanchez-Rodriguez
authors: Luc
authors: L
authors: Tirry
authors: Catherine
authors: C
authors: Blais
authors: Kristof
authors: K
authors: Demeestere
authors: Stefan R
authors: SR
authors: Henz
authors: T Ryan
authors: TR
authors: Gregory
authors: Johannes
authors: J
authors: Mathieu
authors: Lou
authors: L
authors: Verdon
authors: Laurent
authors: L
authors: Farinelli
authors: Jeremy
authors: J
authors: Schmutz
authors: Erika
authors: E
authors: Lindquist
authors: René
authors: R
authors: Feyereisen
authors: Yves
authors: Y
authors: Van de Peer
mesh_terms: D000222:Adaptation, Physiological / Q000235:genetics* / Q000502:physiology; D000818:Animals; D004441:Ecdysterone / Q000031:analogs & derivatives / Q000235:genetics; D019143:Evolution, Molecular; D005349:Fibroins / Q000235:genetics; D005786:Gene Expression Regulation; D022761:Gene Transfer, Horizontal / Q000235:genetics; D005801:Genes, Homeobox / Q000235:genetics; D016678:Genome / Q000235:genetics*; D023281:Genomics; D060434:Herbivory / Q000235:genetics* / Q000502:physiology; D008969:Molecular Sequence Data; D018978:Molting / Q000235:genetics; D005810:Multigene Family / Q000235:genetics; D049329:Nanostructures / Q000737:chemistry; D010944:Plants / Q000469:parasitology; D047011:Silk / Q000096:biosynthesis / Q000737:chemistry; D040102:Tetranychidae / Q000235:genetics* / Q000502:physiology*; D059467:Transcriptome / Q000235:genetics
chemical_list: D047011:Silk; D004441:Ecdysterone; C008999:ponasterone A; D005349:Fibroins