title: Unlocking Hydrogenation for C-C Bond Formation: A Brief Overview of Enantioselective Methods.
abstract: Hydrogenation of π-unsaturated reactants in the presence of carbonyl compounds or imines promotes reductive C-C coupling, providing a byproduct-free alternative to stoichiometric organometallic reagents in an ever-increasing range of C=X (X = O, NR) additions. Under transfer hydrogenation conditions, hydrogen exchange between alcohols and π-unsaturated reactants triggers generation of electrophile-nucleophile pairs, enabling carbonyl addition directly from the alcohol oxidation level, bypassing discrete alcohol oxidation and generation of stoichiometric byproducts.
authors: University of Texas at Austin, Department of Chemistry and Biochemistry, 1 University Station - A5300, Austin, TX 78712-1167, USA.
authors: Abbas
authors: A
authors: Hassan
authors: Michael J
authors: MJ
authors: Krische