title: A ring fragmentation approach to medium-sized cyclic 2-alkynones.
abstract: Bicyclic γ-silyloxy-β-hydroxy-α-diazoketones, in which the Cβ-Cγ bond is the ring fusion bond, productively fragment when treated with tin(IV) chloride to provide medium-sized cyclic 2-alkynones. This method provides good to excellent yields of 10-, 11-, and 12-membered alkynone products.
authors: Department of Chemistry, The University of Vermont, 82 University Place, Burlington, Vermont 05405, USA.
authors: Nikolay P
authors: NP
authors: Tsvetkov
authors: Ali
authors: A
authors: Bayir
authors: Samuel
authors: S
authors: Schneider
authors: Matthias
authors: M
authors: Brewer
mesh_terms: D003516:Cycloparaffins / Q000737:chemistry*; D015394:Molecular Structure
chemical_list: D003516:Cycloparaffins