title: Role of cytoreductive nephrectomy in the era of targeted therapy for renal cell carcinoma.
abstract: With the advent of targeted therapy for the treatment of metastatic renal cancer, the routine use of cytoreductive nephrectomy has been questioned. However, available data suggest that cytoreductive nephrectomy remains an integral part of treatment in properly selected patients. This review details the rationale for the continued use of cytoreductive nephrectomy in acceptable surgical candidates in the era of targeted therapy.
authors: Department of Surgery, University of Kentucky, Lexington, KY 40513, USA.
authors: Paul L
authors: PL
authors: Crispen
authors: Michael L
authors: ML
authors: Blute
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use*; D002292:Carcinoma, Renal Cell / Q000188:drug therapy / Q000556:secondary / Q000601:surgery; D003131:Combined Modality Therapy; D006801:Humans; D007680:Kidney Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000601:surgery; D058990:Molecular Targeted Therapy / Q000379:methods*; D009392:Nephrectomy / Q000379:methods*; D018579:Patient Selection; D016896:Treatment Outcome
chemical_list: D000970:Antineoplastic Agents