title: Synthesis of δ-carbolines via a Pd-catalyzed sequential reaction from 2-iodoanilines and N-tosyl-enynamines.
abstract: A facile Pd-catalyzed sequential reaction has been developed for the synthesis of δ-carbolines from 2-iodoanilines and N-tosyl-enynamines. This protocol involves Larock heteroannulation/elimination/electrocyclization/oxidative aromatization cascade sequences and allows access to multisubstituted δ-carbolines in moderate to good yields.
authors: Key Laboratory of Organosilicon Chemistry and Material Technology of Ministry of Education, Hangzhou Normal University, Wenyi Road 222, Hangzhou 310012, People's Republic of China. caojianhznu@yahoo.cn
authors: Jian
authors: J
authors: Cao
authors: Yongping
authors: Y
authors: Xu
authors: Yulong
authors: Y
authors: Kong
authors: Yuming
authors: Y
authors: Cui
authors: Ziqiang
authors: Z
authors: Hu
authors: Guanhai
authors: G
authors: Wang
authors: Yuan
authors: Y
authors: Deng
authors: Guoqiao
authors: G
authors: Lai
mesh_terms: D000588:Amines / Q000737:chemistry*; D000814:Aniline Compounds / Q000737:chemistry*; D002243:Carbolines / Q000138:chemical synthesis*; D002384:Catalysis; D008958:Models, Molecular; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*
chemical_list: C552400:2-iodobenzenamine; D000588:Amines; D000814:Aniline Compounds; D002243:Carbolines; D010165:Palladium