title: Probing the limitations of the fluorous content for tag-mediated microarray formation.
abstract: The synthesis of a di-perfluorohexyl tag is reported for use in a fluorous-based carbohydrate microarray. A comparative microarray study with this di-perfluorohexyl tag and a mono-perfluorooctyl and mono-perfluorohexyl tag found the increased fluorous content conducive to better spot morphology and easier washing protocols without precluding reuse of the fluorous slide.
authors: Department of Chemistry, Iowa State University, Ames, IA 50011-3111, USA.
authors: Heather D
authors: HD
authors: Edwards
authors: Sahana K
authors: SK
authors: Nagappayya
authors: Nicola L B
authors: NL
authors: Pohl
mesh_terms: D002241:Carbohydrates / Q000032:analysis*; D005453:Fluorescence; D006845:Hydrocarbons, Fluorinated / Q000138:chemical synthesis / Q000737:chemistry*; D046228:Microarray Analysis / Q000379:methods*
chemical_list: D002241:Carbohydrates; D006845:Hydrocarbons, Fluorinated