title: Paediatric moyamoya in mainland France: a comprehensive survey of academic neuropaediatric centres.
abstract: BACKGROUND
  Epidemiological data of paediatric moyamoya disease/syndrome (MMD/MMS) in non-Asian populations are scarce.
  
  
  METHODS
  A questionnaire was sent to every French neuropaediatric academic centre to estimate the prevalence, incidence, familial form rate and location of paediatric MMD/MMS cases. Specific paediatric data were also retrieved from the most recent nationwide Japanese study.
  
  
  RESULTS
  A 100% response rate was obtained. The prevalence of paediatric MMD/MMS was estimated at 0.39/100,000 children (95% CI: 0.28-0.49), and the incidence was estimated at 0.065/100,000 children/year (95% CI: 0.025-0.12), with 7.5% familial cases. The prevalence was homogenous within the different administrative areas.
  
  
  CONCLUSIONS
  This comprehensive survey of MMD/MMS in academic neuropaediatric centres suggests that the prevalence of the disease in children in France is approximately 1/20th of that estimated in Asia.
authors: Paediatric Neurology Department, Hôpital Necker-Enfants Malades, APHP, Paris, France. manoelle.kossorotoff@nck.aphp.fr
authors: M
authors: M
authors: Kossorotoff
authors: D
authors: D
authors: Hervé
authors: F
authors: F
authors: Toulgoat
authors: C
authors: C
authors: Renaud
authors: E
authors: E
authors: Presles
authors: H
authors: H
authors: Chabriat
authors: S
authors: S
authors: Chabrier
mesh_terms: D000046:Academic Medical Centers / Q000706:statistics & numerical data*; D000293:Adolescent; D017677:Age Distribution; D000367:Age Factors; D044466:Asian People / Q000706:statistics & numerical data; D002648:Child; D002675:Child, Preschool; D005602:France / Q000453:epidemiology; D020022:Genetic Predisposition to Disease; D006306:Health Surveys; D006801:Humans; D015994:Incidence; D007564:Japan / Q000453:epidemiology; D009072:Moyamoya Disease / Q000453:epidemiology* / Q000208:ethnology / Q000235:genetics; D015995:Prevalence; D012111:Residence Characteristics; D011795:Surveys and Questionnaires