title: Presurgical neuropsychological and behavioral evaluation of children with posterior fossa tumors.
abstract: OBJECTIVE
  Brain tumors are associated with behavioral and neuropsychological effects. Most available data are focused on the posttreatment neurological and cognitive deficits of these patients. The aim of the present study was to investigate the pretreatment neuropsychological and behavioral impairment in children with posterior fossa tumors.
  
  
  METHODS
  The authors studied 24 children with posterior fossa tumors who were between 4 and 15 years of age, and who were surgically treated at the authors' institute. During the period prior to the tumor excision, neuropsychological and behavioral assessments were performed. A control group of age-matched children was also studied. The children's executive functions were assessed using the short form of the Wechsler Intelligence Scale for Children (WISC). For the assessment of visuospatial functions, spatial memory, and visuomotor integration skills, the Bender-Gestalt Test (BGT) was used. For assessment of the visual perception and visual memory, the authors used the Benton Visual Retention Test (BVRT). Furthermore, parents or caregivers completed the Child Behavior Checklist (CBCL).
  
  
  RESULTS
  The WISC revealed no significant difference between patients and the control group. The CBCL revealed significant somatic concerns compared with the measure's norms. Furthermore, the patients differed in aggressiveness, somatic concerns, anxiety symptoms, internalizing of problems, and total problems. In the BGT and the BVRT results, no significant difference was observed between patients and the control group. Furthermore, no significant correlation was found between neuropsychological scores and sex, age at diagnosis, histological diagnosis, presence of hydrocephalus, degree of hydrocephalus, tumor size, and tumor location.
  
  
  CONCLUSIONS
  Children with posterior fossa tumors suffer more frequently from somatic concerns, aggressiveness, anxiety, and internalizing disorders compared with controls. No difference was found with respect to intelligence scores.
authors: Department of Neurosurgery, Children’s Hospital Agia Sofia, Athens, Greece.
authors: Maria
authors: M
authors: Varela
authors: Magda
authors: M
authors: Liakopoulou
authors: George A
authors: GA
authors: Alexiou
authors: Dimitra
authors: D
authors: Pitsouni
authors: Giorgos A
authors: GA
authors: Alevizopoulos
mesh_terms: D000293:Adolescent; D000374:Aggression / Q000523:psychology*; D001007:Anxiety / Q000523:psychology*; D016022:Case-Control Studies; D002648:Child; D002652:Child Behavior / Q000523:psychology*; D002675:Child, Preschool; D005260:Female; D006801:Humans; D015192:Infratentorial Neoplasms / Q000523:psychology* / Q000601:surgery; D007360:Intelligence; D008297:Male; D008568:Memory; D009043:Motor Activity; D009483:Neuropsychological Tests; D057234:Preoperative Period; D013028:Space Perception; D014796:Visual Perception; D014888:Wechsler Scales