title: Two fiber genes of nearly equal lengths are a common and distinctive feature of Fowl adenovirus C members.
abstract: The complete genome or the genome region containing the two fiber genes of two reference strains and one field isolate representing both serotypes of Fowl adenovirus C were sequenced. Two fiber genes were revealed in the genomes of all three isolates. Fiber-1 and fiber-2 genes of several Fowl adenovirus C isolates were sequenced as well. Both serotypes 4 and 10 have two fiber genes. The genome region containing the fiber gene was also sequenced for the reference strain of Fowl adenovirus B. Just one fiber gene was revealed in this strain. Predicted amino acid sequences were compared to already published fiber sequences of different adenovirus isolates and one amino acid substitution within fiber-2 was detected in all of the Fowl adenovirus C isolates that were isolated from chickens with hepatitis-hydropericardium syndrome in comparison to apathogenic isolates. Phylogenetic analyses provided insights about the evolution of fiber genes in avian adenoviruses and their genetic relationships.
authors: Clinic for Avian, Reptile and Fish Medicine, Department for Farm Animals and Veterinary Public Health, Vetmeduni Vienna, Veterinärplatz 1, 1210 Vienna, Austria. ana.marek@vetmeduni.ac.at
authors: Ana
authors: A
authors: Marek
authors: Viola
authors: V
authors: Nolte
authors: Anna
authors: A
authors: Schachner
authors: Evelyn
authors: E
authors: Berger
authors: Christian
authors: C
authors: Schlötterer
authors: Michael
authors: M
authors: Hess
mesh_terms: D000257:Adenoviridae Infections / Q000662:veterinary* / Q000821:virology; D000595:Amino Acid Sequence; D019943:Amino Acid Substitution; D000818:Animals; D000259:Aviadenovirus / Q000235:genetics*; D001483:Base Sequence; D001715:Bird Diseases / Q000821:virology*; D002645:Chickens / Q000821:virology; D004279:DNA, Viral / Q000235:genetics; D005814:Genes, Viral; D059014:High-Throughput Nucleotide Sequencing; D008969:Molecular Sequence Data; D010802:Phylogeny
chemical_list: D004279:DNA, Viral