title: The yeast Golgi apparatus.
abstract: The Golgi apparatus is an organelle that has been extensively studied in the model eukaryote, yeast. Its morphology varies among yeast species; the Golgi exists as a system of dispersed cisternae in the case of the budding yeast Saccharomyces cerevisiae, whereas the Golgi cisternae in Pichia pastoris and Schizosaccharomyces pombe are organized into stacks. In spite of the different organization, the mechanism of trafficking through the Golgi apparatus is believed to be similar, involving cisternal maturation, in which the resident Golgi proteins are transported backwards while secretory cargo proteins can stay in the cisternae. Questions remain regarding the organization of the yeast Golgi, the regulatory mechanisms that underlie cisternal maturation of the Golgi and transport machinery of cargo proteins through this organelle. Studies using different yeast species have provided hints to these mechanisms.
authors: Molecular Membrane Biology Laboratory, RIKEN Advanced Science Institute, Wako, Saitama, 351-0198, Japan.
authors: Yasuyuki
authors: Y
authors: Suda
authors: Akihiko
authors: A
authors: Nakano
mesh_terms: D001692:Biological Transport; D006056:Golgi Apparatus / Q000378:metabolism*; D008954:Models, Biological; D012441:Saccharomyces cerevisiae / Q000502:physiology*; D015398:Signal Transduction