title: Low glycemic index treatment for epilepsy in tuberous sclerosis complex.
abstract: Retrospective chart review of 15 patients with tuberous sclerosis complex (TSC) who initiated the low glycemic index treatment (LGIT) for epilepsy management at Massachusetts General Hospital over a five-year period. Prior to dietary therapy, this cohort (average age: 8.5 years) had tried an average of 5.8 anti-epileptic drugs with incomplete seizure control. At 6 months on the LGIT, 7/15 (47%) patients experienced >50% reduction in seizure frequency.
authors: Department of Neurology, Massachusetts General Hospital, Boston, MA 02114, United States.
authors: Anna M
authors: AM
authors: Larson
authors: Heidi H
authors: HH
authors: Pfeifer
authors: Elizabeth A
authors: EA
authors: Thiele
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D055423:Diet, Ketogenic / Q000379:methods; D004827:Epilepsy / Q000097:blood* / Q000178:diet therapy* / Q000453:epidemiology; D005260:Female; D038321:Glycemic Index / Q000502:physiology*; D006801:Humans; D007223:Infant; D008297:Male; D012189:Retrospective Studies; D016896:Treatment Outcome; D014402:Tuberous Sclerosis / Q000097:blood* / Q000178:diet therapy* / Q000453:epidemiology; D055815:Young Adult