title: High-sensitivity in vivo THz transmission imaging of early human breast cancer in a subcutaneous xenograft mouse model.
abstract: We performed in vivo THz transmission imaging study on a subcutaneous xenograft mouse model for early human breast cancer detection. With a THz-fiber-scanning transmission imaging system, we continuously monitored the growth of human breast cancer in mice. Our in vivo study not only indicates that THz transmission imaging can distinguish cancer from the surrounding fatty tissue, but also with a high sensitivity. Our in vivo study on the subcutaneous xenograft mouse model will encourage broad and further investigations for future early cancer screening by using THz imaging system.
authors: Department of Electrical Engineering and Graduate Institute of Photonics and Optoelectronics, National Taiwan University, Taipei, 10617, Taiwan.
authors: Hua
authors: H
authors: Chen
authors: Te-Hsuen
authors: TH
authors: Chen
authors: Tzu-Fang
authors: TF
authors: Tseng
authors: Jen-Tang
authors: JT
authors: Lu
authors: Chung-Chiu
authors: CC
authors: Kuo
authors: Shih-Chen
authors: SC
authors: Fu
authors: Wen-Jeng
authors: WJ
authors: Lee
authors: Yuan-Fu
authors: YF
authors: Tsai
authors: Yi-You
authors: YY
authors: Huang
authors: Eric Y
authors: EY
authors: Chuang
authors: Yuh-Jing
authors: YJ
authors: Hwang
authors: Chi-Kuang
authors: CK
authors: Sun
mesh_terms: D000042:Absorption; D000818:Animals; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000473:pathology; D003952:Diagnostic Imaging / Q000379:methods*; D055088:Early Detection of Cancer / Q000379:methods*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D051379:Mice; D008807:Mice, Inbred BALB C; D013057:Spectrum Analysis; D040521:Subcutaneous Tissue / Q000473:pathology*; D023041:Xenograft Model Antitumor Assays