title: [Primary cranial vault lymphoma].
abstract: BACKGROUND
  Primary bone lymphomas account for 3-7% of all malignant bone tumours and less than 2% of lymphomas in adults. Having the cranial vault as their primary location is very infrequent.
  
  
  METHODS
  A 59-year-old female who presented a painful tumour on the cranial vault which, following radical surgical removal, was found to be an ALK-negative primary large-cell lymphoma.
  
  
  CONCLUSIONS
  After reviewing the literature we believe that this is the first case of cranial vault lymphoma in which the translocation of the ALK protein-producing gene has been studied.
authors: Servicio de Neurocirugía, Departamento de Cirugía, Universidad de Santiago de Compostela, Hospital Clínico Universitario de Santiago, Santiago de Compostela, A Coruña, España. danicastrobouzas@yahoo.es
authors: Daniel
authors: D
authors: Castro-Bouzas
authors: Ángel
authors: Á
authors: Prieto-González
authors: Ramón
authors: R
authors: Serramito-García
authors: José M
authors: JM
authors: Santín-Amo
authors: Rosa M
authors: RM
authors: Reyes-Santías
authors: Alfredo G
authors: AG
authors: Allut
authors: Miguel
authors: M
authors: Gelabert-González
mesh_terms: D000077548:Anaplastic Lymphoma Kinase; D005260:Female; D006801:Humans; D016403:Lymphoma, Large B-Cell, Diffuse / Q000175:diagnosis / Q000235:genetics / Q000473:pathology* / Q000601:surgery; D008875:Middle Aged; D020794:Receptor Protein-Tyrosine Kinases / Q000235:genetics / Q000378:metabolism; D012886:Skull / Q000473:pathology*; D012888:Skull Neoplasms / Q000175:diagnosis / Q000235:genetics / Q000473:pathology* / Q000601:surgery; D014057:Tomography, X-Ray Computed
chemical_list: C000626173:ALK protein, human; D000077548:Anaplastic Lymphoma Kinase; D020794:Receptor Protein-Tyrosine Kinases