title: [Therapy in IgA nephropathy--when and how to do it].
abstract: IgA nephropathy is the most common primary glomerulonephritis worldwide. The clinical spectrum covers a wide range of features from minor urinary abnormalities (asymptomatic hematuria and mild proteinuria with normal renal function) to acute and chronic renal insufficiency. Ideally, the goal of treatment would be to correct any defects in IgA1 glycosylation and to modify mesangial deposition or removal of IgA1 deposits. There are only a few randomized controlled trials in IgA nephropathy; for this reason most treatment options are largely based on expert opinion. Authors discuss therapeutic options of different clinical pictures and the optimized renoprotective treatment of all IgA nephropathy patients.
authors: Pécsi Tudományegyetem, Klinikai Központ II. Belgyógyászati Klinika és Nefrológiai Centrum Pécs Pacsirta.
authors: Tibor
authors: T
authors: Vas
authors: Tibor
authors: T
authors: Kovács
authors: István
authors: I
authors: Késoi
authors: Balázs
authors: B
authors: Sági
authors: Péter
authors: P
authors: Degrell
authors: István
authors: I
authors: Wittmann
authors: Judit
authors: J
authors: Nagy
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001323:Autoantibodies / Q000097:blood*; D001324:Autoantigens / Q000097:blood*; D016572:Cyclosporine / Q000627:therapeutic use; D005920:Glomerular Mesangium / Q000276:immunology*; D005922:Glomerulonephritis, IGA / Q000175:diagnosis / Q000188:drug therapy* / Q000276:immunology*; D006801:Humans; D007070:Immunoglobulin A / Q000097:blood; D007074:Immunoglobulin G / Q000097:blood; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D009173:Mycophenolic Acid / Q000031:analogs & derivatives / Q000627:therapeutic use; D012263:Ribonucleosides / Q000627:therapeutic use
chemical_list: D000305:Adrenal Cortex Hormones; D000893:Anti-Inflammatory Agents; D001323:Autoantibodies; D001324:Autoantigens; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007166:Immunosuppressive Agents; D012263:Ribonucleosides; C010052:mizoribine; D016572:Cyclosporine; D009173:Mycophenolic Acid