title: Lack of association between blood-based detection of Trypanosoma cruzi DNA and cardiac involvement in a non-endemic area.
abstract: Cases of chronic Chagas disease have been increasing in non-endemic areas due to the growth in immigration. This study examined the association between positive Trypanosoma cruzi-DNA detection in blood by PCR and presence of chagasic cardiac involvement in a cohort of immigrants in a European city. No association was found in this study between the positive T. cruzi blood PCR and cardiac involvement.
authors: Tropical Medicine and Clinical Parasitology, Infectious Diseases Department, Hospital Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria, Madrid, Spain. ffnorman@gmail.com
authors: F F
authors: FF
authors: Norman
authors: A
authors: A
authors: Pérez-Ayala
authors: J A
authors: JA
authors: Pérez-Molina
authors: M
authors: M
authors: Flores-Chavez
authors: C
authors: C
authors: Cañavate
authors: R
authors: R
authors: López-Vélez
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D015415:Biomarkers / Q000097:blood; D001800:Blood Specimen Collection / Q000379:methods; D002598:Chagas Cardiomyopathy / Q000175:diagnosis* / Q000453:epidemiology; D002908:Chronic Disease; D016054:DNA, Protozoan / Q000097:blood*; D054242:Emigrants and Immigrants; D019353:Endemic Diseases; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016133:Polymerase Chain Reaction / Q000379:methods; D013030:Spain / Q000453:epidemiology; D014349:Trypanosoma cruzi / Q000235:genetics* / Q000302:isolation & purification; D055815:Young Adult
chemical_list: D015415:Biomarkers; D016054:DNA, Protozoan