title: Mean platelet volume is increased in patients with deep vein thrombosis.
abstract: BACKGROUND
  Pulmonary thromboembolism is a serious complication in patients with deep vein thrombosis (DVT). Previous studies have demonstrated that platelet activation occurs in patients with DVT. Mean platelet volume (MPV) is a simple and easy method of assessing platelet function. The aim of this study was to assess the MPV, an indicator of platelet activation in patients with DVT.
  
  
  METHODS
  The study group consisted of 52 patients with newly diagnosed acute DVT. An age-, gender-, and body mass index-matched control group consisted of 30 healthy volunteers. All patients and control participants underwent ultrasonographic examination. We measured the serum MPV values in patients with DVT and control participants.
  
  
  RESULTS
  Mean platelet volume was significantly higher among patients with DVT when compared with the control group (8.6 ± 0.8 vs 7.7 ± 0.9 fL, respectively; P < .001).
  
  
  CONCLUSIONS
  We have shown that MPV was significantly elevated in patients with DVT compared to controls.
authors: Department of Cardiology, Suleyman Demirel University, Faculty of Medicine, Isparta, Turkey. dr.mgulcan@hotmail.com
authors: Mehmet
authors: M
authors: Gulcan
authors: Ercan
authors: E
authors: Varol
authors: Mustafa
authors: M
authors: Etli
authors: Fatih
authors: F
authors: Aksoy
authors: Mustafa
authors: M
authors: Kayan
mesh_terms: D000328:Adult; D000368:Aged; D001792:Blood Platelets; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015539:Platelet Activation; D014463:Ultrasonography; D020246:Venous Thrombosis / Q000097:blood* / Q000000981:diagnostic imaging