title: The prevalence of primary glaucoma in mainland China: a systematic review and meta-analysis.
abstract: OBJECTIVE
  To estimate the prevalence of primary glaucoma in mainland China and to quantify its association with age, sex, and region.
  
  
  METHODS
  Population-based studies that reported the prevalence of primary open-angle glaucoma (POAG) or/and primary angle-closure glaucoma (PACG) among adult populations in mainland China were identified through systematic searches. Fourteen articles providing 12 population-based studies were included. The overall pooled prevalence estimates were calculated using a random-effects model. A logistic metaregression was used to model the associations between the odds ratio (OR) and 95% confidence interval of primary glaucoma and age, sex, and region.
  
  
  RESULTS
  The overall pooled prevalence of POAG was 0.7% (95% confidence interval, 0.4-1.2), and PACG was found in 1.4% (1.0%, 1.7%). The OR per decade increase in age was 1.68 (1.12, 2.52) for POAG, and 2.11 (1.72, 2.60) for PACG. The OR of POAG prevalence was 0.65 (0.26, 1.62) between men and women. Chinese women were 1.75 (1.20, 2.56) times more likely than men to have PACG. The OR between western China and east China were 0.37 (0.10, 1.35) for POAG, and 1.06 (0.63, 1.76) for PACG. The OR between urban China and rural China were 3.92 (1.55, 9.92) for POAG, and 1.07 (0.55, 2.10) for PACG.
  
  
  CONCLUSIONS
  The prevalence of PACG was approximately double that of POAG in adult Chinese. The rate of change of PACG prevalence with age increased more rapidly than that of POAG. The prevalence of POAG in urban was higher than that in rural. PACG was more common in women than in men.
authors: Department of Ophthalmology, Shanghai Changzheng Hospital, Second Military Medical University, Shanghai, China.
authors: Jin-Wei
authors: JW
authors: Cheng
authors: Shi-Wei
authors: SW
authors: Cheng
authors: Xiao-Ye
authors: XY
authors: Ma
authors: Ji-Ping
authors: JP
authors: Cai
authors: You
authors: Y
authors: Li
authors: Rui-Li
authors: RL
authors: Wei
mesh_terms: D017677:Age Distribution; D002681:China / Q000453:epidemiology; D015812:Glaucoma, Angle-Closure / Q000453:epidemiology*; D005902:Glaucoma, Open-Angle / Q000453:epidemiology*; D006801:Humans; D016017:Odds Ratio; D015995:Prevalence; D012424:Rural Population / Q000706:statistics & numerical data; D017678:Sex Distribution; D014505:Urban Population / Q000706:statistics & numerical data