title: [Airway management in a patient with Williams syndrome].
abstract: Williams syndrome is characterized by the triad of supravalvular aortic stenosis (SAS), mental retardation and elfin facies. Generally, difficult airway is expected in patients with Williams syndrome by characteristic face. A 26-year-old female with Williams syndrome was scheduled for abdominal myomectomy under general anesthesia. Difficult mask ventilation and tracheal intubation were anticipated because of micrognathia, mandibular retrusion, and a Mallanpati class III airway. Before induction of anesthesia the patient breathed 100% oxygen for 3 minutes. Anesthesia was induced and maintained with propofol, remifentanil and rocuronium bromide. Mask ventilation was easily performed. The direct laryngoscopic view was Cormack grade I and there was no difficulty in the tracheal intubation. After induction of anesthesia, anesthetic course was uneventful. According to the most previous clinical reports in patients with Williams syndrome in Japan, mask ventilation and tracheal intubation were performed easily contrary to preoperative airway assessment. In view of SAS, mental retardation, airway deformity and airway assessment in previous clinical reports, we should select the optimal strategy for airway management in patients with Williams syndrome.
authors: Department of Anesthesiology, South Miyagi Medical Center Oogawara 989-1253.
authors: Akihiro
authors: A
authors: Kanaya
authors: Tadanobu
authors: T
authors: Yasuda
authors: Akiko
authors: A
authors: Kojima
authors: Toshio
authors: T
authors: Saishu
authors: Shin
authors: S
authors: Kurosawa
mesh_terms: D000328:Adult; D058109:Airway Management / Q000379:methods*; D000768:Anesthesia, General; D005260:Female; D006801:Humans; D007442:Intubation, Intratracheal; D017214:Laryngeal Masks; D007889:Leiomyoma / Q000601:surgery; D014594:Uterine Neoplasms / Q000601:surgery; D018980:Williams Syndrome / Q000150:complications / Q000601:surgery*