title: The influence of Borna disease viral infection on dairy cow reproduction.
abstract: We investigated the influence of Borna disease virus (BDV) infection on the clinical state of dairy cows. Sera from 149 cows were examined using enzyme-linked immunosorbent assay and western blotting detect antibodies to the BDV-nucleoprotein antigen. Among 149 investigated cows, 25 (16.8%) showed a positive reaction to BDV antigen. No significant difference existed in milk production or medical history between seropositive and seronegative cows. Although the estrus cycle appeared normal even in the seropositive cows, the frequency of artificial insemination and calving-to-conception intervals significantly increased in seropositive cows. Therefore, fertilization failure was recognized in the BDV-antibody positive cows.
authors: School of Veterinary Medicine, Rakuno Gakuen University, Ebetsu, Hokkaido 069-8501, Japan. k-hagi@rakuno.ac.jp
authors: Katsuro
authors: K
authors: Hagiwara
authors: Tatsuya
authors: T
authors: Ando
authors: Masateru
authors: M
authors: Koiwa
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000097:blood; D001890:Borna Disease / Q000453:epidemiology / Q000276:immunology / Q000503:physiopathology / Q000821:virology*; D001891:Borna disease virus / Q000302:isolation & purification*; D002417:Cattle; D002418:Cattle Diseases / Q000453:epidemiology / Q000276:immunology / Q000503:physiopathology* / Q000821:virology*; D016009:Chi-Square Distribution; D004797:Enzyme-Linked Immunosorbent Assay / Q000662:veterinary; D005260:Female; D005306:Fertilization / Q000502:physiology; D007564:Japan / Q000453:epidemiology; D007774:Lactation; D008297:Male; D008892:Milk / Q000378:metabolism; D011247:Pregnancy; D012098:Reproduction / Q000502:physiology*; D016036:Seroepidemiologic Studies
chemical_list: D000914:Antibodies, Viral