title: Risk factor analysis for low blood pressure and hyponatremia in acutely and subacutely spinal cord injured patients.
abstract: METHODS
  Case control.
  
  
  OBJECTIVE
  To clarify the predictors of low blood pressure (BP) and hyponatremia after spinal cord injury (SCI) and to discuss their pathophysiology.
  
  
  METHODS
  A SCI center in Japan.
  
  
  METHODS
  Age, gender, initial ASIA impairment scale (AIS) score, BP, blood electrolytes (sodium, K and Cl) and biochemical markers were evaluated at 1 month after injury. Risk factors of low BP and hyponatremia were analyzed using uni- and multivariate logistic regression models.
  
  
  RESULTS
  This study comprised of 172 SCI patients. Initial AIS score (Odds ratio (OR): 1.24, 95% confidence intervals (CI) 1.13-1.49, P-value <0.01) and hyponatremia (OR: 3.71, 95%CI 1.27-6.96, P<0.01) were the most important risk factors of low BP. As a second step, risk factors of hyponatremia were initial AIS score (OR: 1.36, 95%CI 1.08-2.78, P<0.01) and age (OR: 1.55, 95%CI 1.17-2.93, P<0.01).
  
  
  CONCLUSIONS
  In acute and subacute period, the more severe SCI and lower AIS score patients have the more frequently low BP and/or hyponatremia do appear.
authors: Department of Neurosurgery, Tsukazaki Hospital, Himeji, Japan. nakao-ygc@umin.org
authors: Y
authors: Y
authors: Nakao
authors: K
authors: K
authors: Suda
authors: N
authors: N
authors: Shimokawa
authors: Y
authors: Y
authors: Fu
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016022:Case-Control Studies; D015897:Comorbidity / Q000639:trends; D005260:Female; D006801:Humans; D007010:Hyponatremia / Q000175:diagnosis / Q000401:mortality* / Q000503:physiopathology*; D007022:Hypotension / Q000175:diagnosis / Q000401:mortality* / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D013119:Spinal Cord Injuries / Q000175:diagnosis / Q000401:mortality* / Q000503:physiopathology*; D015599:Trauma Severity Indices; D055815:Young Adult