title: DAMPD: a manually curated antimicrobial peptide database.
abstract: The demand for antimicrobial peptides (AMPs) is rising because of the increased occurrence of pathogens that are tolerant or resistant to conventional antibiotics. Since naturally occurring AMPs could serve as templates for the development of new anti-infectious agents to which pathogens are not resistant, a resource that contains relevant information on AMP is of great interest. To that extent, we developed the Dragon Antimicrobial Peptide Database (DAMPD, http://apps.sanbi.ac.za/dampd) that contains 1232 manually curated AMPs. DAMPD is an update and a replacement of the ANTIMIC database. In DAMPD an integrated interface allows in a simple fashion querying based on taxonomy, species, AMP family, citation, keywords and a combination of search terms and fields (Advanced Search). A number of tools such as Blast, ClustalW, HMMER, Hydrocalculator, SignalP, AMP predictor, as well as a number of other resources that provide additional information about the results are also provided and integrated into DAMPD to augment biological analysis of AMPs.
authors: South African National Bioinformatics Institute, The University of the Western Cape, 7535 Bellville, South Africa.
authors: Vijayaraghava
authors: V
authors: Seshadri Sundararajan
authors: Musa Nur
authors: MN
authors: Gabere
authors: Ashley
authors: A
authors: Pretorius
authors: Saleem
authors: S
authors: Adam
authors: Alan
authors: A
authors: Christoffels
authors: Minna
authors: M
authors: Lehväslaiho
authors: John A C
authors: JA
authors: Archer
authors: Vladimir B
authors: VB
authors: Bajic
mesh_terms: D000890:Anti-Infective Agents / Q000737:chemistry*; D023181:Antimicrobial Cationic Peptides / Q000737:chemistry* / Q000235:genetics; D016208:Databases, Factual; D012984:Software
chemical_list: D000890:Anti-Infective Agents; D023181:Antimicrobial Cationic Peptides