title: Extreme thermal sensitivity and pain-induced sensitization in a fibromyalgia patient.
abstract: During the course of a psychophysical study of fibromyalgia syndrome (FMS), one of the subjects with a long history of headache and facial pain displayed an extraordinarily severe thermal allodynia. Her stimulus-response function for ratings of cutaneous heat pain revealed a sensitivity clearly beyond that of normal controls and most FMS subjects. Specially designed psychophysical methods showed that heat sensitivity sometimes increased dramatically within a series of stimuli. Prior exposure to moderate heat pain served as a trigger for allodynic ratings of series of normally neutral thermal stimulation. These observations document a case of breakthrough pain sensitivity with implications for mechanisms of FMS pain.
authors: Department of Prosthodontics, College of Dentistry, University of Florida, D11-006, P.O. Box 100435, FL 32610, USA.
authors: Fong
authors: F
authors: Wong
authors: Anthony
authors: A
authors: Rodrigues
authors: Siegfried
authors: S
authors: Schmidt
authors: Charles J
authors: CJ
authors: Vierck
authors: Andre P
authors: AP
authors: Mauderli