title: [Fungemia in hospitals of the city of Buenos Aires, Argentina].
abstract: BACKGROUND
  The incidence of fungi like pathogens in hospitals varies by regions.
  
  
  OBJECTIVE
  Our goal was not only to record the incidence and etiology of fungaemia, but also the change during the 4 years analysed, to determine the time of detection in automated blood culture and by lysis-centrifugation, and finally to assess the gender, age and underlying disease of the patients with fungaemia.
  
  
  METHODS
  An observational multicentre study of fungaemia was conducted in hospitals in the Mycology Network of Buenos Aires.
  
  
  RESULTS
  A total of 190,920 blood cultures were processed: 182,050 automated blood culture and 8,870 lysis-centrifugation. Fungi were recovered in 1,020 episodes. The overall incidence of fungaemia was 1.72/1,000 admissions; 683 episodes were due to Candida (68%), and 325 (32%) to other fungi: 214 Cryptococcus, 105 Histoplasma, 7 Rhodotorula, 5 Trichosporon, 2 Pichia, 2 Acremonium, one Saccharomyces and one Fusarium. The incidence of candidaemia was 1.15/1,000 admissions with a wide variation between centres (0.35 to 2.65). Most Candida isolates (97%) were detected in the first 2 days of incubation. Candida albicans was recovered in 43% of the episodes. In fungaemia other than candidaemia, the predominant fungi were Cryptococcus and Histoplasma capsulatum.
  
  
  CONCLUSIONS
  The incidence remained stable during the study period. Fungaemia by Candida were predominant. C. albicans was involved in less than a half of the episodes. The recovery of Cryptoccocus and H. capsulatum is strongly associated with HIV patients.
authors: Sección Microbiología, Laboratorio Central, Hospital General de Agudos Dr. C. Argerich, Buenos Aires, Argentina. lauralm.argerich@gmail.com
authors: Laura
authors: L
authors: López Moral
authors: Iris Nora
authors: IN
authors: Tiraboschi
authors: Mariela
authors: M
authors: Schijman
authors: Mario
authors: M
authors: Bianchi
authors: Liliana
authors: L
authors: Guelfand
authors: Silvana
authors: S
authors: Cataldi
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000453:epidemiology / Q000382:microbiology; D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D001118:Argentina / Q000453:epidemiology; D001331:Automation; D058387:Candidemia / Q000453:epidemiology; D002498:Centrifugation; D002648:Child; D002675:Child, Preschool; D003428:Cross Infection / Q000453:epidemiology* / Q000382:microbiology; D003453:Cryptococcosis / Q000453:epidemiology; D005260:Female; D016469:Fungemia / Q000453:epidemiology* / Q000382:microbiology; D006660:Histoplasmosis / Q000453:epidemiology; D006786:Hospitals, Urban / Q000145:classification / Q000706:statistics & numerical data*; D006801:Humans; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D009172:Mycology / Q000379:methods; D011446:Prospective Studies; D017678:Sex Distribution; D013045:Species Specificity; D055815:Young Adult