title: Antibacterial activity of water-soluble extract from pine needles of Cedrus deodara.
abstract: The antibacterial activity of water-soluble extract from pine needles of Cedrus deodara (WEC) was evaluated on five food-borne bacteria, and its related mechanism was investigated by transmission electron microscope. In vitro antibacterial assay showed that WEC possesses a remarkable antibacterial activity against tested food-borne bacteria including Escherichia coli, Proteus vulgaris, Staphylococcus aureus, Bacillus subtilis and Bacillus cereus, with the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) values in the ranges of 0.78-12.5 mg/ml and 1.56-25mg/ml, respectively. In a food system of fresh-squeezed tomato juice, WEC was observed to possess an effective capacity to control the total counts of viable bacteria. Shikimic acid was isolated from WEC and identified as the main antibacterial compound. All results of our study suggested that WEC might be a new potential source of natural antibacterial agents applicable to food.
authors: College of Light Industry, Textile and Food Engineering, Sichuan University, Chengdu 610065, PR China.
authors: Wei-Cai
authors: WC
authors: Zeng
authors: Qiang
authors: Q
authors: He
authors: Qun
authors: Q
authors: Sun
authors: Kai
authors: K
authors: Zhong
authors: Hong
authors: H
authors: Gao
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001409:Bacillus cereus / Q000187:drug effects; D001412:Bacillus subtilis / Q000187:drug effects; D001419:Bacteria / Q000187:drug effects*; D028203:Cedrus; D004926:Escherichia coli / Q000187:drug effects; D005516:Food Microbiology; D008826:Microbial Sensitivity Tests; D010936:Plant Extracts / Q000494:pharmacology; D018515:Plant Leaves; D011514:Proteus vulgaris / Q000187:drug effects; D012765:Shikimic Acid / Q000494:pharmacology*; D013211:Staphylococcus aureus / Q000187:drug effects
chemical_list: D000900:Anti-Bacterial Agents; D010936:Plant Extracts; D012765:Shikimic Acid