title: Use of the telephone-administered Minnesota Cognitive Acuity Screen to detect mild cognitive impairment.
abstract: This study determined the sensitivity and specificity of the telephone-administered Minnesota Cognitive Acuity Screen (MCAS) to distinguish mild cognitive impairment (MCI) from healthy controls (HCs) and from Alzheimer's disease (AD). A total of 100 individuals with MCI, 50 individuals with possible/probable AD, and 50 HCs were screened to exclude medical and psychiatric conditions affecting cognition. In-office evaluation included neuropsychological testing, neurologic examination, and neurodiagnostic work-up. Participants with AD obtained significantly lower MCAS total scores than participants with MCI, who in turn performed worse than the HC group. Sensitivity was 86% and specificity was 78% for distinguishing between MCI and HC. Sensitivity was 86% and specificity was 77% for discriminating between MCI and AD. Sensitivity was 91% and specificity was 78% for discriminating between impaired groups (MCI and AD) and HCs. Results suggest that the MCAS successfully discriminates MCI from HC and AD and has potential as an effective telephone-administered screening tool for memory disorders.
authors: Department of Psychiatry and Human Behavior, Warren Alpert Medical School of Brown University, Providence, RI 02903, USA. gremont@lifespan.org
authors: Geoffrey
authors: G
authors: Tremont
authors: George D
authors: GD
authors: Papandonatos
authors: Beth
authors: B
authors: Springate
authors: Brooke
authors: B
authors: Huminski
authors: Michael D
authors: MD
authors: McQuiggan
authors: Janet
authors: J
authors: Grace
authors: Laura
authors: L
authors: Frakey
authors: Brian R
authors: BR
authors: Ott
mesh_terms: D000368:Aged; D003071:Cognition; D060825:Cognitive Dysfunction / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008297:Male; D009483:Neuropsychological Tests / Q000592:standards; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013689:Telephone