title: [The increase of carbon dyoxidi production at hypoxia in health subjects].
abstract: Pulmonary gas exchange, SpO2 and heart rate at 15-min hypoxia (respiration by air with 0.17; 0.15 and 0.13 oxygen fractions) have been investigated in 24 health subjects. It has been established, results of the group analysis and the results of the individual analysis had been differed. Reaction on hypoxia at the group analysis had been found only at 0.13 02 fraction. It was only hyperventilation. The individual analysis had revealed 4 types of reaction on hypoxia already at 0.17 and 0.15 02 fractions: (1) hyperventilation, (2) decrease of oxygen consumption, (3) increase of ventilation effectiveness, (4) increase of CO2 production. The mechanisms of last reaction are unknown, but we supposed it was connected with anaerobic metabolism. The reactions were detected at light hypoxia (0.17 and 0.15 oxygen fractions) in 90% health subjects when SpO2 decreased to 87-93%. The increase ventilation has been detected at hypoxia within respiration 0.13 oxygen in 60% subjects when SpO2 decreased to 83-87%, while other reactions were nearly absent.
authors: O V
authors: OV
authors: Grishin
authors: S V
authors: SV
authors: Basalaeva
authors: N D
authors: ND
authors: Umantseva
authors: N V
authors: NV
authors: Ustiuzhaninova
authors: V G
authors: VG
authors: Grishin
authors: I M
authors: IM
authors: Mitrofanov
mesh_terms: D000328:Adult; D002245:Carbon Dioxide / Q000378:metabolism*; D005260:Female; D006801:Humans; D000860:Hypoxia / Q000378:metabolism* / Q000503:physiopathology*; D008297:Male; D010101:Oxygen Consumption; D011659:Pulmonary Gas Exchange; D012123:Pulmonary Ventilation
chemical_list: D002245:Carbon Dioxide