title: Bacteremia and MR-proANP changes in mild community-acquired pneumonia.
abstract: BACKGROUND
  Mid-regional pro-atrial natriuretic peptide (MR-proANP) increases with severity in community-acquired pneumonia (CAP). We investigated whether changes of MR-proANP correlated to bacteremia.
  
  
  METHODS
  392 adult patients with CAP visiting emergency department from a prospective observational multicenter study.
  
  
  RESULTS
  MR-proANP levels increased in patients with positive bacteremia (92.8 pmol/L vs. 84.3 pmol/L, p = 0.04). Performance of MR-proANP to detect bacteremia (0.60) was equivalent to CRP (0.59) but less accurate than PCT (0.69).
  
  
  CONCLUSIONS
  MR-ANP poorly predicts bacteremia in CAP patients.
authors: Department of Emergency Medicine, Groupe Hospitalier Broca Cochin Hôtel-Dieu, Paris, France.
authors: Solweig
authors: S
authors: Guinard-Barbier
authors: Camille
authors: C
authors: Chenevier-Gobeaux
authors: Sophie
authors: S
authors: Grabar
authors: Laurent
authors: L
authors: Quinquis
authors: Jeannot
authors: J
authors: Schmidt
authors: Pierre
authors: P
authors: Hausfater
authors: Enrique
authors: E
authors: Casalino
authors: Stéphanie
authors: S
authors: Huet
authors: Jean-Louis
authors: JL
authors: Pourriat
authors: Bertrand
authors: B
authors: Renaud
authors: Yann-Erick
authors: YE
authors: Claessens
mesh_terms: D000328:Adult; D009320:Atrial Natriuretic Factor / Q000378:metabolism*; D016470:Bacteremia / Q000378:metabolism / Q000382:microbiology*; D017714:Community-Acquired Infections / Q000378:metabolism*; D005602:France; D006801:Humans; D008875:Middle Aged; D018410:Pneumonia, Bacterial / Q000378:metabolism*; D011446:Prospective Studies
chemical_list: D009320:Atrial Natriuretic Factor