title: Impact of methadone with versus without drug abuse counseling on HIV risk: 4- and 12-month findings from a clinical trial.
abstract: OBJECTIVE
  Human immunodeficiency virus (HIV)-risk behaviors were examined at 4- and 12-month follow-up for 230 newly admitted methadone patients randomly assigned to receive either methadone only (n = 99) or methadone with drug abuse counseling (n = 131) in the first 4 months of treatment.
  
  
  METHODS
  The AIDS Risk Assessment was administered at baseline (treatment entry) and at 4- and 12-month follow-up. Linear mixed model analysis examined changes in HIV drug- and sex-risk behaviors over the 12 months in the total sample, drug-risk behaviors in the subsample that reported injecting drugs at baseline (n = 110), and sex-risk behaviors in the subsample that reported engaging in unprotected sex at baseline (n = 130).
  
  
  RESULTS
  Significant decreases over time were found in the frequencies of injecting, injecting with other injectors, and sharing cooker, cotton, or rinse water in the total sample and the injector subsample (P < 0.05). Decreases were also found in the frequencies of having sex without a condom either with someone who was not a spouse or primary partner or while high (P < 0.05) in the total sample and the frequencies of having sex without a condom and having sex without a condom while high in the unprotected-sex subsample (P < 0.05). No significant treatment group main effects or Treatment Group × Time interaction effects were found in any of the HIV-risk behaviors in the total sample or either subsample (P > 0.05).
  
  
  CONCLUSIONS
  During the first 12 months of treatment, providing drug abuse counseling with methadone compared with providing methadone alone was not associated with significant changes in HIV-risk behaviors for methadone maintenance patients.
authors: Friends Research Institute, Baltimore, MD 21201, USA. skelly@friendsresearch.org
authors: Sharon M
authors: SM
authors: Kelly
authors: Robert P
authors: RP
authors: Schwartz
authors: Kevin E
authors: KE
authors: Oʼgrady
authors: Devang
authors: D
authors: Gandhi
authors: Jerome H
authors: JH
authors: Jaffe
mesh_terms: D000328:Adult; D015142:Baltimore; D003131:Combined Modality Therapy; D003376:Counseling; D003419:Crisis Intervention; D004305:Dose-Response Relationship, Drug; D005260:Female; D005500:Follow-Up Studies; D015658:HIV Infections / Q000517:prevention & control* / Q000523:psychology / Q000635:transmission*; D007722:Health Knowledge, Attitudes, Practice; D006556:Heroin Dependence / Q000534:rehabilitation*; D006801:Humans; D008297:Male; D008691:Methadone / Q000627:therapeutic use*; D008875:Middle Aged; D009294:Narcotics / Q000627:therapeutic use*; D058850:Opiate Substitution Treatment; D010353:Patient Education as Topic / Q000379:methods; D047568:Unsafe Sex / Q000517:prevention & control / Q000523:psychology
chemical_list: D009294:Narcotics; D008691:Methadone