title: Solitary intracranial Rosai-Dorfman disease: case report and literature review.
abstract: Rosai-Dorfman disease is a well-established autoimmune histioproliferative disorder, and solitary central nervous system involvement is rare. A 35-year-old man presented with headache and transient blurred vision of 4 months' duration and weakness of the left extremities for 1  month. He had left temporal hemianopsia, a right nasal visual field defect of the upper medial quadrant and decreased muscle strength of the left extremities. Magnetic resonance imaging (MRI) showed a contrastenhancing tentorium-based lesion in the right trigone, intruding into the right lateral  ventricle. The lesion was totally resected. Rosai-Dorfman disease was confirmed pathologically by an inflammatory infiltrate in the absence of an infectious agent, emperipolesis and positive S100 staining. From a review of the literature on Rosai-Dorfman disease in the central  nervous system it is concluded that follow-up MRI should be performed in order to detect possible recurrence and that this rare entity should be considered in the differential diagnosis of intracranial lesions.
authors: Department of Neurosurgery, Huashan Hospital affiliated to Fudan University, Shanghai Neurosurgical Centre, Shanghai, China.
authors: X Y
authors: XY
authors: Cao
authors: S H
authors: SH
authors: Luan
authors: W M
authors: WM
authors: Bao
authors: C
authors: C
authors: Shen
authors: B J
authors: BJ
authors: Yang
mesh_terms: D000328:Adult; D001927:Brain Diseases / Q000000981:diagnostic imaging* / Q000601:surgery; D015618:Histiocytosis, Sinus / Q000000981:diagnostic imaging* / Q000601:surgery; D006801:Humans; D008297:Male; D011859:Radiography; D011877:Radionuclide Imaging