title: A case of posterior reversible encephalopathy syndrome in a child with Crohn's disease treated with Infliximab.
abstract: OBJECTIVE
  Posterior reversible encephalopathy syndrome (PRES) is a clinico-radiological entity characterised by headache, seizures, visual disturbance, altered mental status and vasogenic oedema on neuro-imaging. We report a rare case of PRES in a 8-year-old female with Crohn's disease (CD) following Infliximab administration and colectomy.
  
  
  METHODS
  Clinical case reported including a review of current literature regarding PRES and Infliximab.
  
  
  RESULTS
  This is one of several cases of PRES reported recently in proximity to Infliximab administration.
  
  
  CONCLUSIONS
  Awareness of this rare condition in patients receiving immunosuppressive treatment is important to prevent poor outcomes for patients. The increasing number of these cases recognised in patients receiving Infliximab should be kept under close clinical surveillance due to the possibility of a link between the two.
authors: Department of paediatric gastroenterology, Royal Hospital for Sick, Children (Yorkhill), Glasgow, Scotland, United Kingdom.
authors: Rosemary
authors: R
authors: Haddock
authors: Vikki
authors: V
authors: Garrick
authors: Iain
authors: I
authors: Horrocks
authors: Richard K
authors: RK
authors: Russell
mesh_terms: D000893:Anti-Inflammatory Agents / Q000009:adverse effects / Q000627:therapeutic use*; D000911:Antibodies, Monoclonal / Q000009:adverse effects / Q000627:therapeutic use*; D002648:Child; D003082:Colectomy / Q000009:adverse effects; D003424:Crohn Disease / Q000188:drug therapy* / Q000601:surgery; D005260:Female; D006801:Humans; D000069285:Infliximab; D054038:Posterior Leukoencephalopathy Syndrome / Q000175:diagnosis / Q000209:etiology*
chemical_list: D000893:Anti-Inflammatory Agents; D000911:Antibodies, Monoclonal; D000069285:Infliximab