title: Chemical constituents, antioxidant and antimocrobial activity of essential oil of Pogostemon paniculatus (Willd.).
abstract: The essential oil extracted from the leaves of Pogostemon paniculatus (Willd.) Benth. (Lamiaceae), was analysed by gas chromatography-mass spectrometry (GC-MS). Nineteen compounds constituting 85.36% of the total oil were identified in the oil. Patchouli alcohol (30.65%), α-guaiene (10.67%), β-guaiene (9.09%), caryophyllene (8.64%), eicosene (5.27%) were the major constituents present. The essential oil was analysed for antimicrobial activity by disc diffusion assay and minimum inhibition concentration against six bacteria and three fungi. Results showed inhibitory activity against some of the tested microorganisms. The essential oil was also tested for the DPPH free-radical scavenging activity and had an inhibitory concentration (IC(50)) value of 18.5 µg mL(-1).
authors: Plant biotechnology laboratory, Department of Botany, Karnatak University, Dharwad, Karnataka, India.
authors: Godbole
authors: G
authors: Manoj
authors: Shiragambi Hanumantagouda
authors: SH
authors: Manohar
authors: Hosakatte Niranjana
authors: HN
authors: Murthy
mesh_terms: D000975:Antioxidants / Q000737:chemistry* / Q000494:pharmacology; D052176:Azulenes / Q000737:chemistry / Q000494:pharmacology; D008401:Gas Chromatography-Mass Spectrometry; D019686:Lamiaceae / Q000737:chemistry*; D008826:Microbial Sensitivity Tests; D009822:Oils, Volatile / Q000737:chemistry* / Q000494:pharmacology; D018515:Plant Leaves / Q000737:chemistry; D000081223:Polycyclic Sesquiterpenes; D012717:Sesquiterpenes / Q000737:chemistry / Q000494:pharmacology; D045789:Sesquiterpenes, Guaiane / Q000737:chemistry / Q000494:pharmacology
chemical_list: D000975:Antioxidants; D052176:Azulenes; D009822:Oils, Volatile; D000081223:Polycyclic Sesquiterpenes; D012717:Sesquiterpenes; D045789:Sesquiterpenes, Guaiane; C019408:guaiene; C024714:caryophyllene; C052983:patchouli alcohol