title: Breast cancer in the lower jaw after reconstructive surgery with a pectoralis major myocutaneous flap (PMMC) -- a case report.
abstract: For head and neck as well as for oromaxillofacial surgery, the use of the pectoralis major myocutaneous (PMMC) flap is a standard reconstructive technique after radical surgery for cancers in this region. We report to our knowledge for the first development of breast cancer in the PMMC flap in a 79 year old patient, who had undergone several operations in the past for recurring squamous cell carcinoma of the jaw. The occurrence of a secondary malignancy within the donor tissue after flap transfer is rare, but especially in the case of transferred breast tissue and the currently high incidence of breast cancer theoretically possible. Therefore preoperative screening mammography seems advisable to exclude a preexisting breast cancer in female patients undergoing such reconstruction surgery. Therapy for breast cancer under these circumstances is individual and consists of  radical tumor resection followed by radiation if applicable and a standard systemic therapeutic regimen on the background of the patients individual prognosis due to the primary cancer.
authors: Department of Obstetrics, Heinrich Heine University Hospital Düsseldorf, Germany. c.nestle-kraemling@sana-duesseldorf.de
authors: C
authors: C
authors: Nestle-Krämling
authors: N
authors: N
authors: Kübler
authors: W
authors: W
authors: Janni
authors: S
authors: S
authors: Braunstein
authors: W
authors: W
authors: Budach
authors: E
authors: E
authors: Bölke
authors: C
authors: C
authors: Matuschek
authors: R
authors: R
authors: Depprich
mesh_terms: D000368:Aged; D001943:Breast Neoplasms / Q000209:etiology* / Q000473:pathology; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000601:surgery*; D005260:Female; D006258:Head and Neck Neoplasms / Q000473:pathology / Q000601:surgery*; D006801:Humans; D056948:Orthognathic Surgical Procedures; D010369:Pectoralis Muscles / Q000601:surgery*; D013524:Surgical Flaps / Q000473:pathology*