title: High-speed AFM reveals the dynamics of single biomolecules at the nanometer scale.
abstract: Atomic force microscopy allows visualization of biomolecules with nanometer resolution under physiological conditions. Recent advances have improved the time resolution of the technique from minutes to tens of milliseconds, meaning that it is now possible to watch single biomolecules in action in real time. Here, we review this development.
authors: Department of Bionanoscience, Kavli Institute for Nanoscience, Delft University of Technology, Lorentzweg 1, 2628 CJ Delft, The Netherlands.
authors: Allard J
authors: AJ
authors: Katan
authors: Cees
authors: C
authors: Dekker
mesh_terms: D001419:Bacteria / Q000648:ultrastructure; D005057:Eukaryotic Cells / Q000648:ultrastructure; D018625:Microscopy, Atomic Force / Q000379:methods*; D053758:Nanoparticles / Q000737:chemistry / Q000648:ultrastructure*; D036103:Nanotechnology / Q000379:methods