title: Outbreaks of equine grass sickness in Hungary.
abstract: Equine grass sickness (EGS) occurs mainly in Great Britain, but has once been reported in Hungary. The stud which was affected by EGS in 2001 had no new cases until 2009/10, when 11 of 60 and five of 12 one- to three-year-old colts died or were euthanased due to EGS. Following a few hours in the high-risk field during the winter of 2010/11 further four cases of acute EGS were noted among these horses. The affected horses showed somewhat different clinical signs compared with the cases reported in Great Britain. Histopathological findings in these horses were consistent with EGS. In most examined cases carbofuran, a carbamate was found in the liver by toxicological examination, and it is postulated that carbofuran may influence the immune system and therefore predispose the horses to develop EGS. Carbamates are thought to cause a delayed neurotoxicity in human beings. Further studies are needed to clarify the potential role of carbamates in EGS.
authors: Equine Clinic, Section Internal Medicine, University of Veterinary Medicine Vienna, Veterinärplatz, 1 1210, Wien, Austria. bianca.schwarz@vetmeduni.ac.at
authors: B
authors: B
authors: Schwarz
authors: R
authors: R
authors: Brunthaler
authors: C
authors: C
authors: Hahn
authors: R
authors: R
authors: van den Hoven
mesh_terms: D000822:Animal Husbandry / Q000379:methods; D000818:Animals; D001342:Autonomic Nervous System Diseases / Q000453:epidemiology / Q000382:microbiology / Q000662:veterinary*; D001906:Botulism / Q000453:epidemiology / Q000662:veterinary*; D002219:Carbamates / Q000008:administration & dosage / Q000506:poisoning*; D003014:Clostridium botulinum / Q000472:pathogenicity; D004196:Disease Outbreaks / Q000662:veterinary*; D017809:Fatal Outcome; D006734:Horse Diseases / Q000453:epidemiology* / Q000382:microbiology; D006736:Horses; D006814:Hungary / Q000453:epidemiology; D008297:Male
chemical_list: D002219:Carbamates