title: Optical highlighter molecules in neurobiology.
abstract: The development of advanced optical methods has played a key role in propelling progress in neurobiology. Genetically-encoded fluorescent molecules found in nature have enabled labeling of individual neurons to study their physiology and anatomy. Here we discuss the recent use of both native and synthetic optical highlighter proteins to address key problems in neurobiology, including questions relevant to synaptic function, neuroanatomy, and the organization of neural circuits.
authors: Department of Neurobiology, Harvard Medical School, Room 336 Warren Alpert Bldg., 220 Longwood Avenue, Boston, MA 02115, United States. srdatta@hms.harvard.edu
authors: Sandeep Robert
authors: SR
authors: Datta
authors: George H
authors: GH
authors: Patterson
mesh_terms: D000818:Animals; D006801:Humans; D008164:Luminescent Proteins; D008856:Microscopy, Fluorescence / Q000379:methods*; D009446:Neurobiology / Q000379:methods*; D009474:Neurons / Q000166:cytology / Q000502:physiology*; D055095:Optics and Photonics / Q000379:methods
chemical_list: D008164:Luminescent Proteins