title: Multimodality direct coronary imaging with combined near-infrared spectroscopy and intravascular ultrasound: initial US experience.
abstract: Recent studies emphasize the importance of direct intracoronary imaging techniques that provide insights regarding not only lesion architecture but also plaque composition, particularly the presence or absence of lipid-core plaque (LCP). Intracoronary near-infrared spectroscopy (NIRS) is the only validated FDA approved device for in vivo detection of LCP. A recently introduced catheter provides simultaneous NIRS spectral data coregistered with standard intravascular ultrasound (IVUS) images in a single intracoronary pullback. The present series of cases illustrates the unique data obtained by this combined NIRS-IVUS device and highlights its potential clinical applications. © 2012 Wiley Periodicals, Inc.
authors: Department of Cardiovascular Medicine, Beaumont Hospital, Royal Oak, MI, USA. ryan.madder@spectrumhealth.org
authors: Ryan D
authors: RD
authors: Madder
authors: Daniel H
authors: DH
authors: Steinberg
authors: R David
authors: RD
authors: Anderson
mesh_terms: D000368:Aged; D003324:Coronary Artery Disease / Q000175:diagnosis* / Q000378:metabolism; D003331:Coronary Vessels / Q000737:chemistry / Q000000981:diagnostic imaging / Q000473:pathology; D005260:Female; D006801:Humans; D008055:Lipids / Q000032:analysis*; D008297:Male; D008875:Middle Aged; D058226:Plaque, Atherosclerotic / Q000737:chemistry / Q000175:diagnosis*; D019265:Spectroscopy, Near-Infrared / Q000379:methods*; D018084:Ultrasonography, Interventional / Q000379:methods*
chemical_list: D008055:Lipids