title: Auditory event-related potentials in patients with psychotic illness: a 5-year follow-up.
abstract: The auditory processing is diversely impaired in patients with the first-episode psychosis. During acute phase we previously reported reduced amplitudes in attention-dependent auditory evoked electrical brain potentials but not in those of early automatic components. Here seven first-episode patients at the disease onset and 5 years later were studied and compared to control subjects. At follow-up, also the unattended auditory stimuli elicited reduced amplitudes both in primary sensory component (N100, p = .043) and in automatic deviance detection (N200, p = .013) as compared to acute phase. Patients' psychopathology had improved, however they still showed alterations in components detecting automatic stimulus classification which may convey persisting tendency for misinterpretation in auditory perception.
authors: Department of Psychiatry, Kuopio University Hospital, PL 1627, FIN-70211 Kuopio, Finland. minna.valkonen@kuh.fi
authors: Minna
authors: M
authors: Valkonen-Korhonen
authors: Ina M
authors: IM
authors: Tarkka
authors: Ari
authors: A
authors: Pääkkönen
authors: Maija
authors: M
authors: Purhonen
mesh_terms: D000161:Acoustic Stimulation; D000293:Adolescent; D000328:Adult; D001288:Attention / Q000502:physiology; D001303:Auditory Cortex / Q000503:physiopathology*; D001307:Auditory Perception / Q000502:physiology*; D001931:Brain Mapping; D004569:Electroencephalography; D005072:Evoked Potentials, Auditory / Q000502:physiology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011618:Psychotic Disorders / Q000503:physiopathology*; D012559:Schizophrenia / Q000503:physiopathology*