title: Adrenal disorders in pregnancy.
abstract: Adrenal disorders may manifest during pregnancy de novo, or before pregnancy undiagnosed or diagnosed and treated. Adrenal disorders may present as hormonal hypofunction or hyperfunction, or with mass effects or other nonendocrine effects. Pregnancy presents special problems in the evaluation of the hypothalamic-pituitary-adrenal axis in addition to the usual considerations. The renin-angiotensin-aldosterone axis undergoes major changes during pregnancy. Nevertheless, the common adrenal disorders are associated with morbidity during pregnancy and their management is more complicated. A high index of suspicion must be maintained for these disorders lest they go unrecognized and untreated.
authors: Division of Clinical and Molecular Endocrinology, Department of Medicine, Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.
authors: Dima
authors: D
authors: Abdelmannan
authors: David C
authors: DC
authors: Aron
mesh_terms: D000307:Adrenal Gland Diseases / Q000150:complications* / Q000503:physiopathology / Q000628:therapy; D000310:Adrenal Gland Neoplasms / Q000175:diagnosis / Q000628:therapy; D000311:Adrenal Glands / Q000503:physiopathology; D000309:Adrenal Insufficiency / Q000175:diagnosis / Q000628:therapy; D003480:Cushing Syndrome / Q000175:diagnosis / Q000628:therapy; D005260:Female; D005938:Glucocorticoids / Q000502:physiology; D006801:Humans; D006929:Hyperaldosteronism / Q000150:complications / Q000628:therapy; D007031:Hypothalamus / Q000503:physiopathology; D010673:Pheochromocytoma / Q000175:diagnosis / Q000628:therapy; D010902:Pituitary Gland / Q000503:physiopathology; D011247:Pregnancy; D011248:Pregnancy Complications; D011256:Pregnancy Outcome
chemical_list: D005938:Glucocorticoids