title: Chromatin regulation by CRL4 E3 ubiquitin ligases: CUL4B targets WDR5 ubiquitylation in the nucleus.
authors: Tadashi
authors: T
authors: Nakagawa
authors: Yue
authors: Y
authors: Xiong
mesh_terms: D002467:Cell Nucleus / Q000378:metabolism*; D002843:Chromatin / Q000502:physiology*; D044842:Cullin Proteins / Q000378:metabolism*; D005786:Gene Expression Regulation / Q000235:genetics / Q000502:physiology*; D011495:Histone-Lysine N-Methyltransferase / Q000378:metabolism*; D006801:Humans; D047908:Intracellular Signaling Peptides and Proteins; D008954:Models, Biological; D046912:Multiprotein Complexes / Q000378:metabolism; D009687:Nuclear Proteins / Q000378:metabolism*; D044767:Ubiquitin-Protein Ligases / Q000378:metabolism*; D054875:Ubiquitination
chemical_list: C517832:CUL4B protein, human; D002843:Chromatin; D044842:Cullin Proteins; C429530:DTL protein, human; D047908:Intracellular Signaling Peptides and Proteins; D046912:Multiprotein Complexes; D009687:Nuclear Proteins; C502547:WDR5 protein, human; D011495:Histone-Lysine N-Methyltransferase; D044767:Ubiquitin-Protein Ligases