title: Two populations of corticothalamic and interareal corticocortical cells in the subgranular layers of the mouse primary sensory cortices.
abstract: The subgranular layers (layers 5 and 6) of primary sensory cortex provide corticofugal output to thalamus and they also project to the appropriate secondary sensory cortices. Here we injected two combinations of different color retrograde fluorescent markers in the thalamic and cortical targets of these layers from the three primary sensory cortices (somatosensory, auditory, and visual) in mice to examine the degree of overlap between corticothalamic and interareal corticocortical cells in the subgranular layers. We found that, for all three primary sensory cortices, double-labeled cells were extremely rare, indicating that corticothalamic and interareal corticocortical cells in the subgranular layers represent largely independent populations.
authors: Department of Neurobiology, University of Chicago, Abbott J-117, Chicago, Illinois 60637, USA. ipetrof@bsd.uchicago.edu
authors: Iraklis
authors: I
authors: Petrof
authors: Angela N
authors: AN
authors: Viaene
authors: S Murray
authors: SM
authors: Sherman
mesh_terms: D000818:Animals; D002452:Cell Count; D005456:Fluorescent Dyes; D007150:Immunohistochemistry; D051379:Mice; D008807:Mice, Inbred BALB C; D009474:Neurons / Q000166:cytology*; D013003:Somatosensory Cortex / Q000166:cytology*
chemical_list: D005456:Fluorescent Dyes