title: Comparison of T1-weighted in- and out-of-phase single shot magnetization-prepared gradient-recalled-echo with three-dimensional gradient-recalled-echo at 3.0 Tesla: preliminary observations in abdominal studies.
abstract: OBJECTIVE
  To describe in-phase (IP)/out-of-phase (OP) imaging with single shot magnetization-prepared gradient-recalled-echo (MP-GRE) and to compare intra-individually IP/OP MP-GRE with IP/OP three-dimensional gradient-recalled-echo (3D-GRE) at 3.0 Tesla (T).
  
  
  METHODS
  Thirty-six subjects (15 males, 21 females; mean age 46.97 ± 14.97) who had abdominal MRI examinations including precontrast T1-weighted IP/OP MP-GRE, IP/OP 3D-GRE were included in the study. Two radiologists independently evaluated the sequences qualitatively for extent of artifacts, lesion detectability, and conspicuity and subjective grading of liver steatosis. Quantitative evaluation was performed by one radiologist and included liver fat index, liver and spleen SNR, and liver-lesion and liver-spleen CNR.
  
  
  RESULTS
  Respiratory ghosting was more pronounced on 3D-GRE (P < 0.0008). The degrees of parallel imaging residual artifacts, shading and blurring were significantly higher on the 3D-GRE sequences (P < 0.0008). Spatial misregistration and bounce point artifacts were only observed with MP-GRE images. Pixel graininess was more apparent on MP-GRE (P < 0.0008). Lesion detectability, confidence, and conspicuity were considerably higher on MP-GRE. Visual appreciation of steatosis was superior on 3D-GRE. Overall image quality was superior on MP-GRE (P < 0.0008).
  
  
  CONCLUSIONS
  Higher image quality and improved lesion detectability were present with IP/OP MP-GRE technique. Inversion-recovery prepared techniques may represent an important evolution for precontrast T1-weighted image at 3.0T. The good image quality of MP-GRE sequences acquired in a free breathing manner should recommend its use in patients unable to suspend breathing.
authors: Department of Radiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
authors: Ana
authors: A
authors: Ferreira
authors: Miguel
authors: M
authors: Ramalho
authors: Rafael O P
authors: RO
authors: de Campos
authors: Vasco
authors: V
authors: Heredia
authors: Rafael M
authors: RM
authors: Azevedo
authors: Brian
authors: B
authors: Dale
authors: Richard C
authors: RC
authors: Semelka
mesh_terms: D000005:Abdomen; D000704:Analysis of Variance; D016477:Artifacts; D005234:Fatty Liver / Q000175:diagnosis*; D005260:Female; D006801:Humans; D007090:Image Interpretation, Computer-Assisted / Q000379:methods; D021621:Imaging, Three-Dimensional / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D059629:Signal-To-Noise Ratio