title: Direct thrombectomy using the Penumbra thromboaspiration catheter for the treatment of cerebral venous sinus thrombosis.
abstract: OBJECTIVE
  Cerebral venous sinus thrombosis (CVST) is a rare cause of stroke. A 21 year-old female presented to our institution in a rapidly deteriorating neurological state following failed systemic heparin therapy for treatment of superior sagittal sinus (SSS) thrombosis.
  
  
  METHODS
  The patient underwent emergent mechanical thrombectomy of the thrombosed SSS using the 0.054-inch Penumbra catheter. No adjuvant direct pharmacologic and/or mechanical thrombectomy was performed.
  
  
  RESULTS
  Successful venous recanalization was achieved using the Penumbra system. The patient improved symptomatically following the intervention, and she made a complete neurological recovery within 30 days. At 6-month follow-up, the patient had returned to work and school and remained neurologically intact. A repeat MRV showed complete sinus recanalization.
  
  
  CONCLUSIONS
  Direct mechanical thrombectomy using the Penumbra system provided rapid sinus recanalization for the treatment of symptomatic cerebral venous sinus thrombosis. This device is a valuable addition to the neurointerventional armamentarium.
authors: Department of Neurological Surgery, McKnight Brain Institute, University of Florida, Gainesville, Florida, USA. gregory.velat@neurosurgery.ufl.edu
authors: Gregory J
authors: GJ
authors: Velat
authors: Christopher J
authors: CJ
authors: Skowlund
authors: Michael F
authors: MF
authors: Waters
authors: J
authors: J
authors: Mocco
authors: Brian L
authors: BL
authors: Hoh
mesh_terms: D015901:Angiography, Digital Subtraction; D000925:Anticoagulants / Q000627:therapeutic use; D000927:Anticonvulsants / Q000627:therapeutic use; D001921:Brain / Q000000981:diagnostic imaging; D057785:Catheters; D002533:Cerebral Angiography; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D010291:Paresis / Q000209:etiology / Q000628:therapy; D011183:Postoperative Complications / Q000188:drug therapy / Q000209:etiology; D012640:Seizures / Q000188:drug therapy / Q000209:etiology; D012851:Sinus Thrombosis, Intracranial / Q000601:surgery*; D020521:Stroke / Q000209:etiology / Q000628:therapy; D013396:Suction; D017131:Thrombectomy / Q000379:methods*; D014057:Tomography, X-Ray Computed; D014635:Valproic Acid / Q000627:therapeutic use; D014859:Warfarin / Q000627:therapeutic use; D055815:Young Adult
chemical_list: D000925:Anticoagulants; D000927:Anticonvulsants; D014859:Warfarin; D014635:Valproic Acid