title: Grover disease (transient acantholytic dermatosis) induced by anastrozole.
abstract: We present the case of a 79-year-old woman with a history of breast cancer who developed Grover disease (transient acantholytic dermatosis) following initiation of an aromatase inhibitor, anastrozole, as adjunctive treatment of her breast cancer. A number of drugs have been associated with this condition; however, to our knowledge, this case is the first report of anastrozole-induced Grover disease.
authors: Department of Dermatology, Wright State University, Dayton, Ohio, USA.
authors: Joel S
authors: JS
authors: Crockett
authors: Nicole M
authors: NM
authors: Burkemper
mesh_terms: D000051:Acantholysis / Q000139:chemically induced*; D000368:Aged; D000077384:Anastrozole; D047072:Aromatase Inhibitors / Q000009:adverse effects* / Q000627:therapeutic use; D001943:Breast Neoplasms / Q000188:drug therapy; D005260:Female; D006801:Humans; D007057:Ichthyosis / Q000139:chemically induced*; D009570:Nitriles / Q000009:adverse effects* / Q000627:therapeutic use; D014230:Triazoles / Q000009:adverse effects* / Q000627:therapeutic use
chemical_list: D047072:Aromatase Inhibitors; D009570:Nitriles; D014230:Triazoles; D000077384:Anastrozole