title: Dynamics of cerebrospinal fluid flow in slit ventricle syndrome.
abstract: BACKGROUND
  Although slit ventricle syndrome (SVS) is identified as a serious complication in shunt-treated hydrocephalus, cerebral spinal fluid (CSF) flow via external ventricular drainage (EVD) or shunts in SVS have not been studied up to now.
  
  
  METHODS
  A new apparatus (LiquoGuard(®); Möller-Medical, Fulda, Germany) was used for EVD in a child with SVS. The LiquoGuard actively controls CSF drainage, based on intracranial pressure (ICP).
  
  
  RESULTS
  To achieve well-tolerated clinical conditions, an ICP level of 4 mmHg was necessary; realizable by drainage rates between 0 and 35 mL/h. Drainage rate variations typically occurred with repetitive time intervals of 2 h causing a "saw tooth" shaped CSF flow pattern throughout 24 h.
  
  
  CONCLUSIONS
  SVS seems to be characterized largely by quickly varying CSF drainage demands. Whether this is a general phenomenon or just true for this case has still to be studied and needs further clarification.
authors: Department of Neurosurgery, Saarland University, Homburg-Saar, Germany. regina.eymann@uks.eu
authors: Regina
authors: R
authors: Eymann
authors: Melanie
authors: M
authors: Schmitt
authors: Sebastian
authors: S
authors: Antes
authors: Mohammed Ghiat
authors: MG
authors: Shamdeen
authors: Michael
authors: M
authors: Kiefer
mesh_terms: D002555:Cerebrospinal Fluid / Q000502:physiology*; D002557:Cerebrospinal Fluid Shunts / Q000009:adverse effects*; D002648:Child; D005260:Female; D006801:Humans; D006849:Hydrocephalus / Q000601:surgery; D057446:Hydrodynamics; D007427:Intracranial Pressure / Q000502:physiology*; D056124:Slit Ventricle Syndrome / Q000209:etiology*