title: Illuminating the landscape of host-pathogen interactions with the bacterium Listeria monocytogenes.
abstract: Listeria monocytogenes has, in 25 y, become a model in infection biology. Through the analysis of both its saprophytic life and infectious process, new concepts in microbiology, cell biology, and pathogenesis have been discovered. This review will update our knowledge on this intracellular pathogen and highlight the most recent breakthroughs. Promising areas of investigation such as the increasingly recognized relevance for the infectious process, of RNA-mediated regulations in the bacterium, and the role of bacterially controlled posttranslational and epigenetic modifications in the host will also be discussed.
authors: Unité des Interactions Bactéries-Cellules, Département de Biologie Cellulaire et Infection, Institut Pasteur, F-75015 Paris, France. pcossart@pasteur.fr
authors: Pascale
authors: P
authors: Cossart
mesh_terms: D000818:Animals; D015964:Gene Expression Regulation, Bacterial; D016680:Genome, Bacterial / Q000235:genetics*; D023281:Genomics; D054884:Host-Pathogen Interactions; D006801:Humans; D008089:Listeria monocytogenes / Q000235:genetics* / Q000472:pathogenicity / Q000502:physiology*; D008088:Listeriosis / Q000382:microbiology*; D014774:Virulence / Q000235:genetics