title: The evaluation of the effects of hyperbaric oxygen therapy on new bone formation obtained by distraction osteogenesis in terms of consolidation periods.
abstract: OBJECTIVE
  The aim of this study was to evaluate the effect of hyperbaric oxygen therapy on new bone formation obtained by distraction osteogenesis in long- or short-term consolidation periods.
  
  
  METHODS
  Twenty-four rabbits were used. The animals were divided into two groups of 12 animals each, and vertical mandibular distraction osteogenesis was performed. Hyperbaric oxygen therapy was administered in the first group. Each group was subdivided into two subgroups according to the 30- and 60-day consolidation period. The acquired bone amounts were compared according to their radiographic density and histopathology.
  
  
  RESULTS
  Histopathologically, in the experimental group, callus formation was increased and the new bone was more mineralized. According to the radiographic densitometry analyses, there were no statistically significant differences between the 30-day consolidated subgroups of the experimental group and the 60-day consolidated subgroup of the control group (p = 0.873).
  
  
  CONCLUSIONS
  Hyperbaric oxygen therapy can be used to increase the quality and the quantity of bone and to decrease the maturation time which may shorten the consolidation period of vertical distraction osteogenesis.
  
  
  CONCLUSIONS
  The effect of hyperbaric oxygen therapy on vertical distraction osteogenesis procedure according to consolidation periods has been determined. Hyperbaric oxygen therapy may increase the quality and the quantity of bone and shorten the consolidation period.
authors: Ankara Mevki Military Hospital, Ankara, Turkey.
authors: Ibrahim
authors: I
authors: Mutlu
authors: Yavuz Sinan
authors: YS
authors: Aydintug
authors: Ayper
authors: A
authors: Kaya
authors: Gurkan Rasit
authors: GR
authors: Bayar
authors: Berkay Tolga
authors: BT
authors: Suer
authors: Aydin
authors: A
authors: Gulses
mesh_terms: D000818:Animals; D015519:Bone Density / Q000502:physiology; D006931:Hyperbaric Oxygenation / Q000295:instrumentation / Q000379:methods*; D008334:Mandible / Q000000981:diagnostic imaging / Q000601:surgery; D019857:Osteogenesis, Distraction / Q000379:methods*; D011817:Rabbits; D011859:Radiography