title: Effects of blue light-filtering intraocular lenses on the macula, contrast sensitivity, and color vision after a long-term follow-up.
abstract: OBJECTIVE
  To evaluate the possible side effects and potential protection 5 years after implantation of an intraocular lens (IOL) with a blue-light filter (yellow tinted).
  
  
  METHODS
  Ophthalmology Department, University of São Paulo, São Paulo, Brazil.
  
  
  METHODS
  Prospective randomized clinical study.
  
  
  METHODS
  Patients with bilateral visually significant cataract randomly received an ultraviolet (UV) and blue light-filtering IOL (Acrysof Natural SN60AT) in 1 eye and an acrylic UV light-filtering only IOL (Acrysof SA60AT) in the fellow eye. The primary outcome measures were contrast sensitivity, color vision, and macular findings 5 years after surgery.
  
  
  RESULTS
  The study enrolled 60 eyes of 30 patients. There were no significant clinical or optical coherence tomography findings in terms of age-related macular degeneration in any eye. There were no statistically significant differences in central macular thickness between the 2 IOL groups (P=.712). There were also no significant between-group differences under photopic or scotopic conditions at any spatial frequency studied. No statistically significant differences in the color discrimination test were found between the 2 IOL groups (P=.674).
  
  
  CONCLUSIONS
  After 5 years, there were no significant differences in color perception, scotopic contrast sensitivity, or photopic contrast sensitivity between the blue light-filtering (yellow-tinted) IOL and the IOL with a UV-light filter only (untinted). The potential advantage of the tinted IOL in providing protection to macular cells remains unclear.
authors: Ophthalmology Department, University of São Paulo, São Paulo, Brazil.
authors: Newton
authors: N
authors: Kara-Junior
authors: Rodrigo F
authors: RF
authors: Espindola
authors: Beatriz A F
authors: BA
authors: Gomes
authors: Bruna
authors: B
authors: Ventura
authors: David
authors: D
authors: Smadja
authors: Marcony R
authors: MR
authors: Santhiago
mesh_terms: D000180:Acrylic Resins; D003119:Color Perception Tests; D055253:Color Vision / Q000502:physiology*; D015350:Contrast Sensitivity / Q000502:physiology*; D004311:Double-Blind Method; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D019654:Lens Implantation, Intraocular; D007910:Lenses, Intraocular; D008027:Light; D008266:Macula Lutea / Q000502:physiology*; D008268:Macular Degeneration / Q000503:physiopathology / Q000517:prevention & control; D008297:Male; D008875:Middle Aged; D018918:Phacoemulsification; D011446:Prospective Studies; D011474:Prosthesis Design; D012029:Refraction, Ocular / Q000502:physiology; D014792:Visual Acuity / Q000502:physiology
chemical_list: D000180:Acrylic Resins