title: [Research advances of diterpene synthase].
abstract: Diterpenes, an important class of natural compounds, are widely distributed in nature. As the valuable diterpenoids continue to be found, diterpene synthase in the course of diterpene synthesis get as much attention as possible. The multiformity of end-product-diterpenoids were also due to the diversity of diterpene synthase. This paper focuses on the advances in recent biosynthesis pathway of diterpene and types, cloning, catalytic mechanism, synthetic biology application.
authors: Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.
authors: Yun-fei
authors: YF
authors: He
authors: Wei
authors: W
authors: Gao
authors: Ta-si
authors: TS
authors: Liu
authors: Wen-yuan
authors: WY
authors: Li
authors: Lu-qi
authors: LQ
authors: Huang
mesh_terms: D019883:Alkyl and Aryl Transferases / Q000378:metabolism; D053898:Biosynthetic Pathways; D004224:Diterpenes / Q000378:metabolism*; D007535:Isomerases / Q000378:metabolism; D019761:Phosphorus-Oxygen Lyases / Q000378:metabolism; D010940:Plant Proteins / Q000378:metabolism
chemical_list: D004224:Diterpenes; D010940:Plant Proteins; D019883:Alkyl and Aryl Transferases; C090963:ent-kaurene synthetase A; C105712:ent-kaurene synthetase B; C044955:casbene synthetase; D019761:Phosphorus-Oxygen Lyases; D007535:Isomerases; C088741:abietadiene cyclase; C095926:taxa-4(5),11(12)-diene synthase