title: Influence of dietary components on regulatory T cells.
abstract: Common dietary components including vitamins A and D, omega-3 and probiotics are now widely accepted to be essential to protect against many diseases with an inflammatory nature. On the other hand, high-fat diets are documented to exert multiple deleterious effects, including fatty liver diseases. Here we discuss the effect of dietary components on regulatory T cell (Treg) homeostasis, a central element of the immune system to prevent chronic tissue inflammation. Accordingly, evidence on the impact of dietary components on diseases in which Tregs play an influential role will be discussed. We will review chronic tissue-specific autoimmune and inflammatory conditions such as inflammatory bowel disease, type 1 diabetes mellitus, multiple sclerosis, rheumatoid arthritis and allergies among chronic diseases where dietary factors could have a direct influence via modulation of Tregs homeostasis and functions.
authors: Biotech Research and Innovation Centre, University of Copenhagen, Copenhagen, Denmark. shohreh.issazadeh@bric.ku.dk
authors: Shohreh
authors: S
authors: Issazadeh-Navikas
authors: Roman
authors: R
authors: Teimer
authors: Robert
authors: R
authors: Bockermann
mesh_terms: D000818:Animals; D059305:Diet, High-Fat / Q000009:adverse effects; D019587:Dietary Supplements; D015525:Fatty Acids, Omega-3 / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D007249:Inflammation / Q000188:drug therapy / Q000276:immunology; D050378:T-Lymphocytes, Regulatory / Q000187:drug effects / Q000276:immunology*; D014815:Vitamins / Q000008:administration & dosage / Q000627:therapeutic use
chemical_list: D015525:Fatty Acids, Omega-3; D014815:Vitamins