title: Retrospective analysis of mammographic findings for Japanese women: a potential predictor for breast malignancies.
abstract: This purpose of this study was to retrospectively stratify the risks of malignancy according to the mammographic characteristics of Japanese women. We studied the mammographic findings of 1267 Japanese women. We characterized malignant phenotypes according to mass shape, margin and mass density, and by shape and distribution of calcified foci, and to obtain possible predictors for malignancies according to age groups. Lobular and irregular mass shape, no circumscribed margin and higher density turned out to be more powerful predictors for malignancy than other radiological factors (P < 0.001, respectively). The ratio of the cases detected as a mass in those between 21 and 49 years was lower than that of other age groups. In addition, the presence of calcifications and no mammographic abnormalities were the most powerful predictors for malignancies in the young age groups (P < 0.001, respectively). The peak age of breast cancer is between 40 and 49 years in Japan. In the present study, subtle differences were found in the mammographic results for young and old women, in contrast to those of women in the USA and Europe. The results of this study might enable more accurate prediction of biological behavior of the breast lesions in Japanese women.
authors: Department of Breast Surgery, Nahanishi Clinic, Okinawa, Japan. nahanisikenta@yahoo.co.jp
authors: Kentaro
authors: K
authors: Tamaki
authors: Takanori
authors: T
authors: Ishida
authors: Minoru
authors: M
authors: Miyashita
authors: Masakazu
authors: M
authors: Amari
authors: Noriaki
authors: N
authors: Ohuchi
authors: Kano
authors: K
authors: Uehara
authors: Yoshihiko
authors: Y
authors: Kamada
authors: Nobumitsu
authors: N
authors: Tamaki
authors: Hironobu
authors: H
authors: Sasano
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001940:Breast / Q000473:pathology*; D001943:Breast Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology*; D002114:Calcinosis / Q000000981:diagnostic imaging / Q000473:pathology; D005260:Female; D006801:Humans; D007564:Japan; D008327:Mammography; D008875:Middle Aged; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D055815:Young Adult