title: Effects of exogenous carbon monoxide on radiation-induced bystander effect in zebrafish embryos in vivo.
abstract: In the present work, the influence of a low concentration of exogenous carbon monoxide (CO) liberated from tricarbonylchloro(glycinato)ruthenium (II) (CORM-3) on the radiation induced bystander effect (RIBE) in vivo between embryos of the zebrafish was studied. RIBE was assessed through the number of apoptotic signals revealed on embryos at 25 h post fertilization (hpf). A significant attenuation of apoptosis on the bystander embryos induced by RIBE in a CO concentration dependent manner was observed.
authors: Department of Physics and Materials Science, City University of Hong Kong, Tat Chee Avenue, Kowloon Tong, Hong Kong.
authors: V W Y
authors: VW
authors: Choi
authors: M Y P
authors: MY
authors: Wong
authors: S H
authors: SH
authors: Cheng
authors: K N
authors: KN
authors: Yu
mesh_terms: D000818:Animals; D017209:Apoptosis / Q000187:drug effects / Q000528:radiation effects; D024201:Bystander Effect / Q000187:drug effects*; D002248:Carbon Monoxide / Q000494:pharmacology*; D004625:Embryo, Nonmammalian / Q000187:drug effects* / Q000528:radiation effects; D015027:Zebrafish / Q000196:embryology*
chemical_list: D002248:Carbon Monoxide