title: Total syntheses of angelicoin A, hericenone J, and hericenol A via migratory prenyl- and geranylation-aromatization sequences.
abstract: A five-step synthesis of the natural product angelicoin A using a late stage highly regioselective palladium(0)-catalyzed decarboxylative prenyl migration and aromatization sequence as the key step is reported. The method was extended with geranyl migration in eight-step total syntheses of hericenone J and hericenol A from geraniol.
authors: Department of Chemistry, Imperial College, London, SW7 2AZ, England.
authors: Jens
authors: J
authors: Cordes
authors: Frederick
authors: F
authors: Calo
authors: Katie
authors: K
authors: Anderson
authors: Toni
authors: T
authors: Pfaffeneder
authors: Sylvain
authors: S
authors: Laclef
authors: Andrew J P
authors: AJ
authors: White
authors: Anthony G M
authors: AG
authors: Barrett
mesh_terms: D000080462:Acyclic Monoterpenes; D002384:Catalysis; D015394:Molecular Structure; D009387:Neoprene / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry; D010636:Phenols / Q000138:chemical synthesis* / Q000737:chemistry*; D013237:Stereoisomerism; D013729:Terpenes / Q000138:chemical synthesis* / Q000737:chemistry*
chemical_list: D000080462:Acyclic Monoterpenes; D010636:Phenols; D013729:Terpenes; C572532:hericenol A; C535186:hericenone J; C016077:prenyl; D010165:Palladium; D009387:Neoprene; C007836:geraniol