title: Erythema multiforme-like drug reaction to sorafenib.
abstract: The authors present a case of erythema multiforme-like drug reaction to the multikinase inhibitor sorafenib. While considered targeted therapy, multikinase inhibitors have been demonstrated to have various cutaneous effects. It is important to distinguish allergic reactions from adverse side effects as the latter may permit cautious re-challenge with medications that can potentially prolong survival in patients with advanced or metastatic disease.
authors: New York University Langone Medical Center, New York, NY 10016, USA.
authors: Jesse
authors: J
authors: Lewin
authors: Rachel
authors: R
authors: Farley-Loftus
authors: Miriam Keltz
authors: MK
authors: Pomeranz
mesh_terms: D000328:Adult; D001557:Benzenesulfonates / Q000009:adverse effects*; D003937:Diagnosis, Differential; D003875:Drug Eruptions / Q000209:etiology*; D004892:Erythema Multiforme / Q000139:chemically induced* / Q000473:pathology; D005260:Female; D006229:Hand Dermatoses / Q000139:chemically induced* / Q000473:pathology; D006801:Humans; D009536:Niacinamide / Q000031:analogs & derivatives; D010671:Phenylurea Compounds; D047428:Protein Kinase Inhibitors / Q000009:adverse effects*; D011725:Pyridines / Q000009:adverse effects*; D000077157:Sorafenib
chemical_list: D001557:Benzenesulfonates; D010671:Phenylurea Compounds; D047428:Protein Kinase Inhibitors; D011725:Pyridines; D009536:Niacinamide; D000077157:Sorafenib