title: Diffusive gradients in thin films (DGT) for the prediction of bioavailability of heavy metals in contaminated soils to earthworm (Eisenia foetida) and oral bioavailable concentrations.
abstract: The applicability of diffusive gradients in thin-films (DGT) as a biomimic surrogate was investigated to determine the bioavailable heavy metal concentrations to earthworm (Eisenia foetida). The relationships between the amount of DGT and earthworm uptake; DGT uptake and the bioavailable concentrations of heavy metals in soils were evaluated. The one-compartment model for the dynamic uptake of heavy metals in the soil fitted well to both the earthworm (R(2)=0.641-0.990) and DGT (R(2)=0.473-0.998) uptake data. DGT uptake was linearly correlated with the total heavy metal concentrations in the soil (aqua regia), the bioavailable heavy metal concentrations estimated by fractions I+II of the standard measurements and testing (SM&T) and physiologically based extraction test (PBET, stomach+intestine). The coefficients of determination (R(2)) of DGT uptake vs. aqua regia were 0.433, 0.929 and 0.723; vs. SM&T fractions (I+II) were 0.901, 0.882 and 0.713 and vs. PBET (stomach+intestine) were 0.913, 0.850 and 0.649 for Pb, Zn and Cu, respectively. These results imply that DGT can be used as a biomimic surrogate for the earthworm uptake of heavy metals in contaminated soils as well as predict bioavailable concentrations of heavy metals estimated by SM&T (I+II) and PBET as a human oral bioavailable concentrations of heavy metals.
authors: Department of Environmental Engineering, Kyungpook National University, 1370 Sankyuk-Dong, Buk-Gu, Daegu 702-701, South Korea.
authors: Rabindra
authors: R
authors: Bade
authors: Sanghwa
authors: S
authors: Oh
authors: Won Sik
authors: WS
authors: Shin
mesh_terms: D000818:Animals; D001682:Biological Availability; D040761:Biomimetic Materials; D004058:Diffusion; D004784:Environmental Monitoring / Q000295:instrumentation / Q000379:methods*; D019216:Metals, Heavy / Q000032:analysis / Q000493:pharmacokinetics*; D009835:Oligochaeta / Q000378:metabolism*; D012987:Soil / Q000737:chemistry; D012989:Soil Pollutants / Q000032:analysis / Q000493:pharmacokinetics
chemical_list: D019216:Metals, Heavy; D012987:Soil; D012989:Soil Pollutants