title: Endoscopic vs. open surgery for treating large, locally advanced juvenile angiofibromas: a comparison of local control and morbidity outcomes.
abstract: Juvenile nasopharyngeal angiofibroma is a combined vascular and fibrous neoplasm that most commonly affects prepubertal and adolescent boys. These tumors have traditionally been managed with open surgery, but interest in endoscopic resection-particularly for small tumors-has increased in recent years. To the best of our knowledge, no comparative study of open and endoscopic approaches for treating large, locally advanced tumors has been previously published in the literature. We conducted a retrospective study of 42 males, aged 6 to 21 years (mean: 13 ± 2.1), who had been treated for histologically proven and locally advanced juvenile nasopharyngeal angiofibroma with either open surgery (n = 29) or endoscopic excision (n = 13). Our two primary outcomes measures were local control and surgical morbidity. We found that the endoscopic approach was as good as or better than open approaches for patients with large tumors.
authors: Department of Otolaryngology, Faculty of Medicine, Cairo University, 7 Mahmoud Afifi St., Almaza, Cairo, Egypt 11341.
authors: Hossam
authors: H
authors: Bosraty
authors: Ahmed
authors: A
authors: Atef
authors: Mossad
authors: M
authors: Aziz
mesh_terms: D000293:Adolescent; D000328:Adult; D018322:Angiofibroma / Q000473:pathology / Q000601:surgery*; D002648:Child; D004724:Endoscopy; D006801:Humans; D008297:Male; D009303:Nasopharyngeal Neoplasms / Q000473:pathology / Q000601:surgery*; D009364:Neoplasm Recurrence, Local / Q000473:pathology*; D018365:Neoplasm, Residual; D011183:Postoperative Complications / Q000209:etiology*; D012189:Retrospective Studies; D016896:Treatment Outcome; D055815:Young Adult