title: Trends in incidence and outcome of out-of-hospital cardiac arrest among people with validated myocardial infarction.
abstract: OBJECTIVE
  To describe trends in incidence, outcome, and background characteristics among people who suffered an out-of-hospital cardiac arrest with validated myocardial infarction aetiology (OHCA-V).
  
  
  RESULTS
  People from the northern Sweden MONICA myocardial registry (1989-2007) with OHCA-V (n = 2977) were divided in two age groups (25-64 and 65-74 years). Both those who were resuscitated outside hospital and those who died before resuscitation was started were included in the study. The younger age group was studied during 1989-2007 and the older group during 2000-2007. The incidence of OHCA-V decreased in both the younger group (men p < 0.0001, women p = 0.04) and the older group (men p < 0.0001, women p < 0.0007, respectively). The proportion with a history of ischaemic heart disease prior to the event decreased (p < 0.0001). The proportion of previous myocardial infarction decreased (p < 0.0001), diabetes mellitus increased (p = 0.001), coronary interventions increased (p < 0.0001), and survival after OHCA-V increased (p < 0.0001) in the younger group but not in the older group. Long-term survival after OHCA-V was better in the younger than in the older group (p = 0.026).
  
  
  CONCLUSIONS
  The incidence of OHCA-V decreased in both sexes. The proportion surviving after OHCA-V was small but increased, and long-term survival (≥ 28 days) was better in the younger age group. Primary preventive measures may explain most of the improvements. However, the effects of secondary preventive measures cannot be excluded.
authors: The Northern Sweden MONICA Myocardial Registry, Department of Research, Norrbotten County Council, Luleå, Sweden. ann-sofie.forslund@nll.se
authors: Ann-Sofie
authors: AS
authors: Forslund
authors: Siv
authors: S
authors: Söderberg
authors: Jan-Håkan
authors: JH
authors: Jansson
authors: Dan
authors: D
authors: Lundblad
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D016887:Cardiopulmonary Resuscitation; D016009:Chi-Square Distribution; D015897:Comorbidity; D005260:Female; D006801:Humans; D015994:Incidence; D053208:Kaplan-Meier Estimate; D016014:Linear Models; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000175:diagnosis / Q000453:epidemiology* / Q000401:mortality / Q000628:therapy; D058687:Out-of-Hospital Cardiac Arrest / Q000175:diagnosis / Q000453:epidemiology* / Q000401:mortality / Q000628:therapy; D011322:Primary Prevention / Q000639:trends; D012042:Registries; D012307:Risk Factors; D055502:Secondary Prevention / Q000639:trends; D012737:Sex Factors; D017741:Survivors / Q000706:statistics & numerical data; D013548:Sweden / Q000453:epidemiology; D013997:Time Factors; D016896:Treatment Outcome