title: Molecular and physiological characterization of the Arabidopsis thaliana Oxidation-related Zinc Finger 2, a plasma membrane protein involved in ABA and salt stress response through the ABI2-mediated signaling pathway.
abstract: CCCH-type zinc finger proteins are important for developmental and environmental responses. However, the precise roles of these proteins in plant stress tolerance are poorly understood. Arabidopsis thaliana Oxidation-related Zinc Finger 2 (AtOZF2) (At4g29190) is an AtOZF1 homolog previously isolated from Arabidopsis, which confers oxidative stress tolerance on plants. The AtOZF2 protein is localized in the plasma membrane, as is AtOZF1. Disruption expression of AtOZF2 led to reduced root length and leaf size. AtOZF2 was implicated to be involved in the ABA and salinity responses. atozf2 antisense lines were more sensitive to ABA and salt stress during the seed germination and cotyledon greening processes. In contrast, AtOZF2-overexpressing plants were more insensitive to ABA and salt stress than the wild type. Interestingly, in the presence of ABA and salt stress, the transcript level of ABA insensitive 2 (ABI2), but not that of ABI1, in AtOZF2-overexpressing plants was lower than that in the wild type, whereas the expression of ABI2 in atozf2 was significantly enhanced. Thus, AtOZF2 is involved in the ABA and salt stress response through the ABI2-mediated signaling pathway. Taken together, these findings provide compelling evidence that AtOZF2 is an important regulator for plant tolerance to abiotic stress.
authors: Department of Plant Biotechnology, Chonnam National University, Gwangju 500-757, Korea.
authors: Ping
authors: P
authors: Huang
authors: Hyun-Woo
authors: HW
authors: Ju
authors: Ji-Hee
authors: JH
authors: Min
authors: Xia
authors: X
authors: Zhang
authors: Jung-Sung
authors: JS
authors: Chung
authors: Hyeon-Sook
authors: HS
authors: Cheong
authors: Cheol Soo
authors: CS
authors: Kim
mesh_terms: D000040:Abscisic Acid / Q000494:pharmacology*; D000222:Adaptation, Physiological / Q000187:drug effects / Q000235:genetics; D017360:Arabidopsis / Q000235:genetics* / Q000502:physiology; D029681:Arabidopsis Proteins / Q000235:genetics* / Q000378:metabolism; D002352:Carrier Proteins / Q000235:genetics* / Q000378:metabolism; D002462:Cell Membrane / Q000187:drug effects / Q000378:metabolism*; D018506:Gene Expression Regulation, Plant / Q000187:drug effects; D055785:Gene Knockdown Techniques; D017343:Genes, Plant / Q000235:genetics; D005966:Glucuronidase / Q000378:metabolism; D009929:Organ Size / Q000187:drug effects / Q000235:genetics; D010084:Oxidation-Reduction / Q000187:drug effects; D010641:Phenotype; D010749:Phosphoprotein Phosphatases / Q000235:genetics / Q000378:metabolism*; D018515:Plant Leaves / Q000033:anatomy & histology / Q000187:drug effects / Q000235:genetics; D018517:Plant Roots / Q000033:anatomy & histology / Q000187:drug effects / Q000235:genetics; D030821:Plants, Genetically Modified; D021381:Protein Transport / Q000187:drug effects; D016372:RNA, Antisense / Q000235:genetics; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism; D015398:Signal Transduction / Q000187:drug effects / Q000235:genetics; D012965:Sodium Chloride / Q000494:pharmacology*; D013312:Stress, Physiological / Q000187:drug effects* / Q000235:genetics; D013347:Subcellular Fractions / Q000187:drug effects / Q000378:metabolism; D016335:Zinc Fingers
chemical_list: D029681:Arabidopsis Proteins; D002352:Carrier Proteins; C571991:OZF2 protein, Arabidopsis; D016372:RNA, Antisense; D012333:RNA, Messenger; D012965:Sodium Chloride; D000040:Abscisic Acid; C106443:ABI2 protein, Arabidopsis; D010749:Phosphoprotein Phosphatases; D005966:Glucuronidase