title: Developments in coupled solid-phase extraction-capillary electrophoresis 2009-2011.
abstract: This article presents an overview of the design and application of coupled solid-phase extraction-capillary electrophoresis (SPE-CE) systems that have been reported in the literature between January 2009 and July 2011. The present paper is an update of two previous review papers covering the years 2000-2009 (Electrophoresis 2008, 29, 108-128; Electrophoresis 2010, 31, 44-54). Both in-line and on-line SPE-CE approaches are treated and outlined. Attention is paid to emerging technological developments, such as the use of carbon nanotubes and magnetic particles for on-line extraction of sample components prior to CE analysis. Selected examples illustrate the applicability of SPE-CE in biomedical, pharmaceutical, environmental and food analysis. A full overview of recent SPE-CE studies is given in table format, providing information about sample type, SPE sorbent, coupling mode, detection mode and limit of detection. Finally, some general conclusions and future perspectives are given.
authors: Biomolecular Analysis, Department of Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands. R.Ramautar@lumc.nl
authors: Rawi
authors: R
authors: Ramautar
authors: Gerhardus J de
authors: GJ
authors: Jong
authors: Govert W
authors: GW
authors: Somsen
mesh_terms: D001798:Blood Proteins / Q000032:analysis; D019075:Electrophoresis, Capillary; D005504:Food Analysis; D006801:Humans; D059346:Magnets; D037742:Nanotubes, Carbon / Q000737:chemistry; D004364:Pharmaceutical Preparations / Q000032:analysis / Q000097:blood / Q000652:urine; D045483:Rivers / Q000737:chemistry; D052616:Solid Phase Extraction
chemical_list: D001798:Blood Proteins; D037742:Nanotubes, Carbon; D004364:Pharmaceutical Preparations