title: Characteristics of children with sporadic hemolytic uremic syndrome in a single Northern California center.
abstract: OBJECTIVE
  Hemolytic uremic syndrome (HUS) is a frequent cause of acute kidney injury in children. The aim of this study is to describe our experience at a Northern California center.
  
  
  METHODS
  Medical records of children suffered from HUS (08/99 to 03/09) at University of California Davis Medical Center were reviewed.
  
  
  RESULTS
  Forty-six children (70% girls) were studied, and their median age was 3.5 years. Diarrhea was a presenting symptom in 42 subjects (91%), and hematochezia was present in 31 children (67%). Escherichia coli 0157:H7 was isolated in 20 patients (44%). Thirteen subjects (28%) underwent dialysis for a median of 7 days during their hospitalization. Follow-up was achieved in 36 patients (78.3%) for a median of 16 months. One patient required angiotensin-converting enzyme (ACE) inhibitor for proteinuria but none was on dialysis.
  
  
  CONCLUSIONS
  In our cohort in children with HUS in a single Californian center, long-term complications were uncommon during a median follow-up time of 16 months.
authors: Division of Nephrology, Department of Pediatrics, Stanford University, 300 Pasteur Drive, G306 MC 5208 Stanford, Palo Alto, CA 94305, USA. gjoh@stanford.edu
authors: Gia
authors: G
authors: Oh
authors: Keith K
authors: KK
authors: Lau
mesh_terms: D000293:Adolescent; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000627:therapeutic use; D001002:Anuria / Q000209:etiology; D001794:Blood Pressure; D001806:Blood Urea Nitrogen; D002140:California; D016009:Chi-Square Distribution; D002648:Child; D002675:Child, Preschool; D003404:Creatinine / Q000097:blood / Q000652:urine; D003956:Dialysis; D003967:Diarrhea / Q000209:etiology; D004926:Escherichia coli / Q000302:isolation & purification; D005260:Female; D005500:Follow-Up Studies; D006471:Gastrointestinal Hemorrhage / Q000209:etiology*; D005919:Glomerular Filtration Rate; D006463:Hemolytic-Uremic Syndrome / Q000150:complications* / Q000382:microbiology / Q000503:physiopathology* / Q000628:therapy; D006801:Humans; D007223:Infant; D007902:Length of Stay; D008297:Male; D011507:Proteinuria / Q000188:drug therapy / Q000209:etiology; D012002:Rectal Diseases / Q000209:etiology*; D012189:Retrospective Studies; D018709:Statistics, Nonparametric
chemical_list: D000806:Angiotensin-Converting Enzyme Inhibitors; D003404:Creatinine