title: The impact of omic technologies on the study of food microbes.
abstract: The advent of the molecular biology era in the 1950s and the subsequent emergence of new technologies positively impacted on all areas of biology. New discoveries in molecular biology and experimental tools were developed over the next 60 years that have revolutionized the study of food microbiology. Previously, food microbiology relied on classic microbiology techniques, which had remained relatively unchanged since the discoveries of Louis Pasteur in the 1800s. More recently, new advances resulting in "omic" technologies have exploded the areas of genomics, transcriptomics, and proteomics and revealed many fundamental processes driven by both pathogens and commensals. This review outlines advances in omic technologies and how these have impacted food microbiology through providing examples of recently published landmark work.
authors: Department of Food, Bioprocessing and Nutrition Sciences, North Carolina State University, Raleigh, North Carolina 27695, USA.
authors: Sarah
authors: S
authors: O'Flaherty
authors: Todd R
authors: TR
authors: Klaenhammer
mesh_terms: D000818:Animals; D057005:Bioengineering; D005516:Food Microbiology / Q000379:methods*; D005517:Foodborne Diseases / Q000517:prevention & control; D020869:Gene Expression Profiling; D023281:Genomics / Q000379:methods*; D006090:Gram-Negative Bacteria / Q000145:classification / Q000235:genetics / Q000302:isolation & purification / Q000378:metabolism; D006094:Gram-Positive Bacteria / Q000145:classification / Q000235:genetics / Q000302:isolation & purification / Q000378:metabolism; D059014:High-Throughput Nucleotide Sequencing; D006801:Humans; D056186:Metagenomics / Q000379:methods; D058889:Molecular Typing; D040901:Proteomics / Q000379:methods; D059467:Transcriptome