title: Cytomegalovirus colitis and viremia from mycophenolate mofetil monotherapy in birdshot chorioretinopathy.
abstract: OBJECTIVE
  To describe a case of cytomegalovirus (CMV) viremia and colitis in a patient on mycophenolate mofetil (MMF) monotherapy for birdshot chorioretinopathy.
  
  
  METHODS
  Case report.
  
  
  METHODS
  Retrospective chart review.
  
  
  RESULTS
  Treatment with MMF 1.5 g twice daily for 5 years led to leucopenia and a CD4 count of 299, which resulted in active CMV infection.
  
  
  CONCLUSIONS
  Treatment with MMF alone may put otherwise immune-competent individuals at risk for opportunistic CMV infection. Greater awareness of this association may allow for better monitoring, earlier detection, and treatment of future cases.
authors: Seth M
authors: SM
authors: Pantanelli
authors: Yousuf M
authors: YM
authors: Khalifa
mesh_terms: D000328:Adult; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects* / Q000627:therapeutic use; D000998:Antiviral Agents / Q000627:therapeutic use; D000080365:Birdshot Chorioretinopathy; D018791:CD4 Lymphocyte Count; D002825:Chorioretinitis / Q000188:drug therapy*; D003092:Colitis / Q000175:diagnosis* / Q000821:virology; D003586:Cytomegalovirus Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology; D004359:Drug Therapy, Combination; D015774:Ganciclovir / Q000031:analogs & derivatives / Q000627:therapeutic use; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects / Q000627:therapeutic use; D007970:Leukopenia / Q000139:chemically induced; D008297:Male; D009173:Mycophenolic Acid / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000627:therapeutic use; D011241:Prednisone / Q000627:therapeutic use; D016896:Treatment Outcome; D000077562:Valganciclovir; D014766:Viremia / Q000175:diagnosis / Q000821:virology*
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D000998:Antiviral Agents; D007166:Immunosuppressive Agents; D000077562:Valganciclovir; D009173:Mycophenolic Acid; D015774:Ganciclovir; D011241:Prednisone