title: Evaluation of a prescription strength 4% hydroquinone/10% L-ascorbic acid treatment system for normal to oily skin.
abstract: BACKGROUND
  A 4% hydroquinone/10% L-ascorbic acid treatment system aims to treat early signs of photodamage in normal to oily skin and help prevent further photodamage. The system also contains vitamin E, witch hazel, aloe barbadensis leaf juice, penetration-enhancing ingredients, micronized zinc oxide, and octinoxate.
  
  
  METHODS
  Patients with minimal or mild facial photodamage and hyperpigmentation, and normal to oily facial skin, used the treatment system for 12 weeks.
  
  
  RESULTS
  Of 34 females enrolled, 30 completed. Median scores for the overall integrated assessment of photodamage, overall intensity of pigmentation, fine lines and wrinkles, tactile roughness, and laxity were significantly improved at week 12 compared with baseline. Furthermore, ≥ 90 percent of patients considered their skin was smoother, softer, more evenly toned, and more radiant, and 100 percent were satisfied with the overall appearance of their skin.
  
  
  CONCLUSIONS
  The treatment system can help to ameliorate early signs of photodamage in normal to oily skin.
authors: Suzanne Bruce and Associates, PA, Houston, TX, USA. sbruce@sba-skincare.com
authors: Suzanne
authors: S
authors: Bruce
authors: JoAnne
authors: J
authors: Watson
mesh_terms: D000328:Adult; D001205:Ascorbic Acid / Q000627:therapeutic use*; D003879:Dermatologic Agents / Q000627:therapeutic use*; D004338:Drug Combinations; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006873:Hydroquinones / Q000627:therapeutic use*; D017495:Hyperpigmentation / Q000188:drug therapy*; D017060:Patient Satisfaction / Q000706:statistics & numerical data; D012629:Sebum / Q000187:drug effects*; D012720:Severity of Illness Index; D015595:Skin Aging / Q000187:drug effects*; D017592:Skin Care / Q000379:methods*; D016896:Treatment Outcome
chemical_list: D003879:Dermatologic Agents; D004338:Drug Combinations; D006873:Hydroquinones; D001205:Ascorbic Acid; C031927:hydroquinone