title: The relationship between nasal index and nasal airway resistance, and response to a topical decongestant.
abstract: The differences in the shape and size of the nose have been proposed to be an adaptation to climate with broad noses (platyrrhine) evolving in a warm humid environment where there was little need for air conditioning and narrow noses (leptorrhine) evolving in colder climates where the air needed more warming. The main aim of this research was to determine if there was any relationship between the shape of the nose as expressed in terms of nasal height and width (nasal index) and total nasal airway resistance (NAR), as one would predict that the narrower leptorrhine noses would have a greater resistance to air flow than the broader platyrrhine noses. It was also proposed that the narrow leptorrhine nose would have better developed vascular tissue than the broad platyrrhine nose in order to condition cold air, and would exhibit a greater response to nasal decongestion. No correlation was found between nasal index and NAR (r = -0.09) and similarly no correlation was found between nasal index and response to a topical nasal decongestant (r = 0.02). The absence of any physiological differences between the different nose types may be due to acclimatisation of participants to the area of recruitment.
authors: Common Cold Centre and Healthcare Clinical Trials, Cardiff School of Biosciences, Cardiff University, Cardiff, UK.
authors: N M
authors: NM
authors: Doddi
authors: R
authors: R
authors: Eccles
mesh_terms: D000064:Acclimatization / Q000502:physiology; D000293:Adolescent; D000328:Adult; D000403:Airway Resistance / Q000187:drug effects*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D014663:Nasal Decongestants / Q000494:pharmacology*; D009666:Nose / Q000033:anatomy & histology* / Q000502:physiology*; D018579:Patient Selection; D010865:Pilot Projects; D025363:Rhinomanometry; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D014663:Nasal Decongestants