title: Formation of structured polygonal nanoparticles by phase-separated comb-like polymers.
abstract: A simple approach using comb-like polymers that undergo nanophase separation between the polyester backbone and the stearoyl side chains is proposed for the preparation of structured non-spherical nanoparticles from a nanoemulsion. Depending on the degree of esterification of the OH groups of poly(glycerol adipate) differently ordered nanostructures is obtained. A perfect lamellar arrangement is obtained for polymers with a high degree of esterification and leads to spherical nanoparticles with an internal onion-like structure. However, when the degree of esterification is only 20 mol%, polygonal nanoparticles with an internal pseudo-hexagonal structure are obtained. The differences in the nanoparticle shapes are related to the volume fraction of the paraffinic pool.
authors: Institute of Pharmacy, Martin Luther University, Halle-Wittenberg, 06099 Halle (Saale), Germany.
authors: Verena M
authors: VM
authors: Weiss
authors: Toufik
authors: T
authors: Naolou
authors: Elkin
authors: E
authors: Amado
authors: Karsten
authors: K
authors: Busse
authors: Karsten
authors: K
authors: Mäder
authors: Jörg
authors: J
authors: Kressler
mesh_terms: D060326:Chemistry Techniques, Synthetic / Q000379:methods*; D004951:Esterification; D015394:Molecular Structure; D053758:Nanoparticles / Q000737:chemistry*; D011108:Polymers / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D011108:Polymers