title: Diabetes mellitus and survival in cystic fibrosis patients after lung transplantation.
abstract: BACKGROUND
  Diabetes mellitus (DM) is common in CF and associated with more severe disease. It is unclear whether DM influences outcome of lung transplantation (LTx).
  
  
  METHODS
  One hundred twenty-three CF patients evaluated for LTx at our centre were included. Survival was calculated.
  
  
  RESULTS
  Patients with and without DM did not differ with regard to gender, age, FEV(1) and BMI prior to LTx. Eighty patients (65%) had a diagnosis of DM before and 13 (11%) only after LTx. Recipients with DM had a significantly higher 1- and 5-year survival (89% and 71%) than those without (71% and 51%). In the multivariate Cox-regression analysis, DM had no impact on LTx-survival.
  
  
  CONCLUSIONS
  One- and five-year survival rates after LTx tend to be better in CF recipients with DM compared to those without DM. No impact of DM on the development of BOS was found.
authors: Division of Pulmonary Medicine, University Hospital, 8091 Zurich, Switzerland.
authors: Markus
authors: M
authors: Hofer
authors: Christoph
authors: C
authors: Schmid
authors: Christian
authors: C
authors: Benden
authors: Rudolf
authors: R
authors: Speich
authors: Ilhan
authors: I
authors: Inci
authors: Walter
authors: W
authors: Weder
authors: Annette
authors: A
authors: Boehler
mesh_terms: D000328:Adult; D001786:Blood Glucose / Q000032:analysis; D001989:Bronchiolitis Obliterans / Q000453:epidemiology; D003550:Cystic Fibrosis / Q000453:epidemiology* / Q000235:genetics / Q000401:mortality; D019005:Cystic Fibrosis Transmembrane Conductance Regulator / Q000235:genetics; D003920:Diabetes Mellitus / Q000453:epidemiology*; D005260:Female; D005541:Forced Expiratory Volume; D006442:Glycated Hemoglobin; D006801:Humans; D016040:Lung Transplantation / Q000401:mortality; D008297:Male; D012189:Retrospective Studies; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D001786:Blood Glucose; D019005:Cystic Fibrosis Transmembrane Conductance Regulator; D006442:Glycated Hemoglobin; C505032:CFTR protein, human