title: Tissue physiology and pathology of aromatase.
abstract: Aromatase is expressed in multiple tissues, indicating a crucial role for locally produced oestrogens in the differentiation, regulation and normal function of several organs and processes. This review is an overview of the role of aromatase in different tissues under normal physiological conditions and its contribution to the development of some oestrogen-related pathologies.
authors: Department of Physiology and Biophysics, College of Medicine, University of Illinois at Chicago, Chicago, IL 60612, United States. costocco@uic.edu
authors: Carlos
authors: C
authors: Stocco
mesh_terms: D000273:Adipose Tissue / Q000201:enzymology / Q000473:pathology; D000728:Androgens / Q000502:physiology; D000818:Animals; D001141:Aromatase / Q000502:physiology*; D001842:Bone and Bones / Q000201:enzymology / Q000473:pathology; D001921:Brain / Q000502:physiology*; D001943:Breast Neoplasms / Q000201:enzymology / Q000473:pathology; D004715:Endometriosis / Q000201:enzymology / Q000473:pathology; D004967:Estrogens / Q000502:physiology*; D005260:Female; D006066:Gonads / Q000502:physiology*; D006801:Humans; D008297:Male; D010920:Placenta / Q000502:physiology; D011247:Pregnancy; D011467:Prostate / Q000502:physiology; D012098:Reproduction / Q000502:physiology*; D012725:Sexual Behavior; D012726:Sexual Behavior, Animal
chemical_list: D000728:Androgens; D004967:Estrogens; D001141:Aromatase