title: Residue depletion of albendazole and its metabolites in aquacultured yellow perch (Perca flavescens).
abstract: Metabolism and residue depletion studies are conducted to determine the marker residue (MR) of a drug in a target tissue of food animals. The MR is used to monitor potential unauthorized use of drugs. The current work is a continuation of our efforts to study metabolism and depletion profiles of albendazole in multiple finfish species to determine a common MR. The results of this study suggest that albendazole sulfone metabolite could potentially serve as MR for albendazole in yellow perch muscle, similar to channel catfish and hybrid striped bass as reported previously by us.
authors.affiliation: US Food and Drug Administration, Center for Veterinary Medicine, Office of Research, Laurel, MD 20708, USA.
authors.forename: D
authors.initials: D
authors.lastname: Yu
authors.forename: E R
authors.initials: ER
authors.lastname: Evans
authors.forename: N
authors.initials: N
authors.lastname: Hasbrouck
authors.forename: R
authors.initials: R
authors.lastname: Reimschuessel
authors.forename: B
authors.initials: B
authors.lastname: Shaikh
mesh_terms: D015766:Albendazole / Q000737:chemistry / Q000378:metabolism / Q000493:pharmacokinetics*; D000818:Animals; D000871:Anthelmintics / Q000737:chemistry / Q000378:metabolism / Q000493:pharmacokinetics*; D017756:Aquaculture; D004350:Drug Residues / Q000378:metabolism*; D006207:Half-Life; D010471:Perches / Q000097:blood*
chemical_list: D000871:Anthelmintics; D015766:Albendazole