title: Atypical presentation of Salzmann nodular degeneration diagnosed with ultra-high-resolution optical coherence tomography.
abstract: A 59-year-old woman presented with bilateral, peripheral, circular corneal infiltrates. There was a clear zone separating the outer margin of the degeneration from the limbus in both eyes. The inner margins were indistinct. Ultra-high-resolution optical coherence tomography (UHR-OCT) imaging demonstrated subepithelial infiltrations with epithelial thinning and corneal surface elevation. The infiltrate was accompanied by significant stromal scarring, which reached deep layers of the corneal stroma. UHR-OCT findings were consistent with Salzmann nodular degeneration. UHR-OCT can be used as an optical biopsy to diagnose atypical corneal degenerations without tissue sampling.
authors.affiliation: Bascom Palmer Eye Institute, University of Miami, Miller School of Medicine, Miami, Florida 33136, USA.
authors.forename: Volkan
authors.initials: V
authors.lastname: Hurmeric
authors.forename: Sonia H
authors.initials: SH
authors.lastname: Yoo
authors.forename: Anat
authors.initials: A
authors.lastname: Galor
authors.forename: Ana Paula
authors.initials: AP
authors.lastname: Canto
authors.forename: Jianhua
authors.initials: J
authors.lastname: Wang
mesh_terms: D003316:Corneal Diseases / Q000175:diagnosis*; D019573:Epithelium, Corneal; D005260:Female; D006801:Humans; D018613:Microscopy, Confocal; D008875:Middle Aged; D041623:Tomography, Optical Coherence / Q000379:methods*; D014792:Visual Acuity