title: CTX-M-15 extended-spectrum β-lactamase in a shiga toxin-producing Escherichia coli isolate of serotype O111:H8.
abstract: We report the discovery of a CTX-M-15-producing Escherichia coli (STEC) of serogroup O111:H8, a major serotype responsible for human enterohemorrhagic Escherichia coli (EHEC) infections. In line with the recent CTX-M-15/O104:H4 E. coli outbreak, these data may reflect an accelerating spread of resistance to expanded-spectrum cephalosporins within the E. coli population, including STEC isolates.
authors.affiliation: Unité Antibiorésistance et Virulence Bactériennes, ANSES Site de Lyon, Lyon, France. charlotte.valat@anses.fr
authors.forename: Charlotte
authors.initials: C
authors.lastname: Valat
authors.forename: Marisa
authors.initials: M
authors.lastname: Haenni
authors.forename: Estelle
authors.initials: E
authors.lastname: Saras
authors.forename: Frédéric
authors.initials: F
authors.lastname: Auvray
authors.forename: Karine
authors.initials: K
authors.lastname: Forest
authors.forename: Eric
authors.initials: E
authors.lastname: Oswald
authors.forename: Jean-Yves
authors.initials: JY
authors.lastname: Madec
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D002511:Cephalosporins / Q000494:pharmacology; D004927:Escherichia coli Infections / Q000382:microbiology; D006801:Humans; D012703:Serotyping; D054323:Shiga-Toxigenic Escherichia coli / Q000201:enzymology* / Q000235:genetics / Q000302:isolation & purification; D018440:beta-Lactam Resistance; D001618:beta-Lactamases / Q000235:genetics / Q000378:metabolism*
chemical_list: D000900:Anti-Bacterial Agents; D002511:Cephalosporins; C473109:beta-lactamase CTX-M-15; D001618:beta-Lactamases