title: Acrogigantism and facial asymmetry: McCune-Albright syndrome.
abstract: McCune-Albright syndrome (MAS) is characterized by a triad of poly/monoostotic fibrous dysplasia, café-au-lait macules and hyperfunctioning endocrinopathies. Association of MAS with GH excess is rare, and in most of the instances somatotropinoma has not been documented. Treatment of patients of MAS with acromegaly is difficult because of thickened calvarium and dysplastic skull bone. We report a 17-year-old girl, who presented with cranio-facial fibrous dysplasia, café-au-lait macules and also had acromegaly due to pituitary macroadenoma, and treated with gamma knife radiosurgery.
authors.affiliation: Department of Endocrinology, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.
authors.forename: Sridhar
authors.initials: S
authors.lastname: Subbiah
authors.forename: Gaurav
authors.initials: G
authors.lastname: Palikhe
authors.forename: Sanjay Kumar
authors.initials: SK
authors.lastname: Bhadada
authors.forename: Kanchan Kumar
authors.initials: KK
authors.lastname: Mukherjee
authors.forename: Anil
authors.initials: A
authors.lastname: Bhansali
mesh_terms: D000172:Acromegaly / Q000209:etiology / Q000473:pathology* / Q000601:surgery; D000236:Adenoma / Q000601:surgery; D000293:Adolescent; D005146:Facial Asymmetry / Q000000981:diagnostic imaging / Q000209:etiology / Q000473:pathology*; D005260:Female; D005359:Fibrous Dysplasia, Polyostotic / Q000150:complications / Q000473:pathology* / Q000601:surgery; D005877:Gigantism / Q000209:etiology / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D010911:Pituitary Neoplasms / Q000601:surgery; D016634:Radiosurgery; D014057:Tomography, X-Ray Computed