title: A simple and an efficient strategy to synthesize multi-component nanocomposites for biosensor applications.
abstract: We demonstrate that core-shell multi-component nanocomposites can be grown in situ at room temperature by a novel one-step approach without adding any reductant and stabilizer. We have presented a one-step method for the synthesis of multi-component nanocomposites in water solution, the multi-component nanocomposites could be produced directly and quickly in an in situ wet-chemical reaction. Here, Au-polypyrrole (PPy)/Prussian blue (PB) nanocomposites have been synthesized successfully under the same circumstance. With the addition of pyrrole monomers into mixture solutions, the autopolymerization of pyrrole into PPy and AuCl(4)(-) was reduced to elemental Au instantaneously as well as simultaneously. At the same time, PB produced along with elemental Au serving as a catalyst. Furthermore, we investigated the performance of Au-PPy/PB nanocomposites as amperometric sensor toward the reduction of H(2)O(2), which displayed high sensitivity, fast response and good stability. The peak current of H(2)O(2) increased linearly with the concentration of H(2)O(2) in the range from 2.5×10(-9) to 1.2×10(-6)M, and the low detection limit of 8.3×10(-10)M (S/N=3) was obtained. Therefore, this work provides a new pathway to design and fabricate novel multi-component nanocomposites, which have unique characteristics and hold great applications in the fields of sensors, electrocatalysis and others.
authors.affiliation: Key Laboratory of Bioelectrochemistry & Environmental Analysis of Gansu Province, College of Chemistry & Chemical Engineering, Northwest Normal University, Lanzhou, China. luxq@nwnu.edu.cn
authors.forename: Xiaoquan
authors.initials: X
authors.lastname: Lu
authors.forename: Yan
authors.initials: Y
authors.lastname: Li
authors.forename: Xia
authors.initials: X
authors.lastname: Zhang
authors.forename: Jie
authors.initials: J
authors.lastname: Du
authors.forename: Xibin
authors.initials: X
authors.lastname: Zhou
authors.forename: Zhonghua
authors.initials: Z
authors.lastname: Xue
authors.forename: Xiuhui
authors.initials: X
authors.lastname: Liu
mesh_terms: D015374:Biosensing Techniques / Q000379:methods*; D005295:Ferrocyanides / Q000737:chemistry*; D006046:Gold / Q000737:chemistry*; D046529:Microscopy, Electron, Transmission; D015394:Molecular Structure; D053761:Nanocomposites / Q000737:chemistry*; D010084:Oxidation-Reduction; D011108:Polymers / Q000737:chemistry*; D011758:Pyrroles / Q000737:chemistry*; D014961:X-Ray Diffraction
chemical_list: D005295:Ferrocyanides; D011108:Polymers; D011758:Pyrroles; C067635:polypyrrole; D006046:Gold; C000170:ferric ferrocyanide