title: Neuropsychological and neurophysiological effects of strengthening exercise for early dementia: a pilot study.
abstract: Research demonstrates a positive effect of aerobic exercise on cognitive functioning in older adults. Unfortunately, aerobic exercise is often contraindicated for older adults due to cardiovascular and functional limitations. Low-intensity strengthening exercise may offer a practical alternative, but the neuropsychological benefits and potential neurophysiological mechanisms are less well understood. The current study evaluated the effects of a 10-week strengthening exercise intervention on cognitive functioning and EEG in a sample of 13 older adults with early dementia, and 9 normative controls. Results revealed beneficial effects of strengthening exercise on verbal memory coupled with frontal beta and delta power asymmetries and N200 amplitude asymmetry. Results point to increased cognitive efficiency following 10 weeks of strengthening exercise. The findings suggest it is feasible to conduct a strengthening intervention with early dementia patients, and to gather neuropsychological and neurophysiological data to evaluate outcomes. Strengthening exercise may serve as a useful alternative to aerobic exercise.
authors.affiliation: Healthy Aging & Neuropsychology Laboratory, Union College, Schenectady, NY 12308, USA.
authors.forename: Vadim
authors.initials: V
authors.lastname: Yerokhin
authors.forename: Cay
authors.initials: C
authors.lastname: Anderson-Hanley
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Hogan
authors.forename: Mina
authors.initials: M
authors.lastname: Dunnam
authors.forename: Daniel
authors.initials: D
authors.lastname: Huber
authors.forename: Sandra
authors.initials: S
authors.lastname: Osborne
authors.forename: Mollie
authors.initials: M
authors.lastname: Shulan
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003704:Dementia / Q000503:physiopathology* / Q000628:therapy*; D004569:Electroencephalography; D005071:Evoked Potentials; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D010865:Pilot Projects; D055070:Resistance Training / Q000379:methods*; D013997:Time Factors; D016896:Treatment Outcome