title: Localized primary cutaneous nodular amyloidosis: case report.
abstract: Amyloidosis results from deposition of fibrous and insoluble amyloid protein in extracellular spaces of organs and tissues. Amyloid deposition can be localized or systemic and either primary or secondary. We report a case of localized primary cutaneous nodular amyloidosis manifested by papular-nodular, reddish-brown lesions affecting the nasal area, without evidence of systemic involvement. Immunohistochemistry showed the presence of immunoglobulin kappa light chain.
authors.affiliation: Fundação Alfredo da Matta, Manaus, AM, Brasil.
authors.forename: Januário de
authors.initials: Jd
authors.lastname: Souza Júnior
authors.forename: Renata Almeida
authors.initials: RA
authors.lastname: Schettini
authors.forename: Walquíria Lima
authors.initials: WL
authors.lastname: Tupinambá
authors.forename: Antonio Pedro Mendes
authors.initials: AP
authors.lastname: Schettini
authors.forename: Carlos Alberto Rodrigues
authors.initials: CA
authors.lastname: Chirano
authors.forename: Cesare
authors.initials: C
authors.lastname: Massone
mesh_terms: D000328:Adult; D000686:Amyloidosis / Q000473:pathology*; D006801:Humans; D000075363:Immunoglobulin Light-chain Amyloidosis; D007150:Immunohistochemistry; D008297:Male; D012871:Skin Diseases / Q000473:pathology*; D012875:Skin Diseases, Metabolic / Q000473:pathology*