title: Comparison of multidetector CT and endoscopic ultrasonography in malignant pancreatic mass lesions.
abstract: OBJECTIVE
  Endoscopic ultrasonography (EUS) has been shown to be superior to conventional CT in detecting and staging pancreatic cancer. We conducted a prospective trial to compare EUS and MDCT, in discriminating benign/malignant, in determining local and vascular invasion of a suspected pancreatic cancer and deciding its resectability.
  
  
  METHODS
  The study was performed at the Gastroenterology Department of Izmir Ataturk Training and Research Hospital, from June 2009 to June 2010, all patients with suspected pancreatic and periampullary tumors referred to our department were enrolled. A total of 56 patients were evaluated at the beginning. Five patients having distal CBD tumor (n=2), gallbladder tumor (n=1) and papillary tumor (n=2) were excluded from the study. Analysis was done for the remaining 51 patients.
  
  
  RESULTS
  For the diagnosis of resectability/unresectability, EUS alone demonstrated a definite role in 4 (9%) of the 43 patients in confirming surgical and pathologic results and MDCT alone demonstrated a definite role in 6 (14%) of the 43 patients in confirming their results. An accurate diagnostic decision regarding resectability/unresectability was accomplished in 27 (63%) patients with EUS and MDCT.
  
  
  CONCLUSIONS
  While MDCT is clinically quite effective, in terms of a correct resectability/unresectability decision, EUS should also be used.
authors.affiliation: Department of Gastroenterology, Izmir Ataturk Training and Research Hospital, Izmir, Turkey. mahmutarabuk@gmail.com
authors.forename: Mahmut
authors.initials: M
authors.lastname: Arabul
authors.forename: Funda
authors.initials: F
authors.lastname: Karakus
authors.forename: Emrah
authors.initials: E
authors.lastname: Alper
authors.forename: Altay
authors.initials: A
authors.lastname: Kandemir
authors.forename: Mustafa
authors.initials: M
authors.lastname: Celik
authors.forename: Volkan
authors.initials: V
authors.lastname: Karakus
authors.forename: Kamil
authors.initials: K
authors.lastname: Yucel
authors.forename: Belkis
authors.initials: B
authors.lastname: Unsal
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D019540:Area Under Curve; D044963:Biopsy, Fine-Needle; D001808:Blood Vessels / Q000473:pathology; D019160:Endosonography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D061330:Multidetector Computed Tomography; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D010190:Pancreatic Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D012372:ROC Curve