title: Illuminating synapse-specific homeostatic plasticity.
abstract: Homeostatic plasticity can globally scale the strength of all synapses on a neuron, but whether a similar bidirectional homeostatic scaling can also operate independently at individual synapses was unknown until now. Here, Man and colleagues demonstrate that single synapses show an input-specific homeostatic downregulation of synaptic efficacy in response to increased activity.
authors.affiliation: Brain Research Centre and Department of Medicine, Vancouver Coastal Health Research Institute, University of British Columbia, V6T 2B5 Vancouver, British Columbia, Canada.
authors.forename: Thomas E
authors.initials: TE
authors.lastname: Bartlett
authors.forename: Yu Tian
authors.initials: YT
authors.lastname: Wang