title: Reconstruction for limited-projection fluorescence molecular tomography based on projected restarted conjugate gradient normal residual.
abstract: Limited-projection fluorescence molecular tomography (FMT) can greatly reduce the acquisition time, which is suitable for resolving fast biology processes in vivo but suffers from severe ill-posedness because of the reconstruction using only limited projections. To overcome the severe ill-posedness, we report a reconstruction method based on the projected restarted conjugate gradient normal residual. The reconstruction results of two phantom experiments demonstrate that the proposed method is feasible for limited-projection FMT.
authors.affiliation: Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing 10084, China.
authors.forename: Xu
authors.initials: X
authors.lastname: Cao
authors.forename: Bin
authors.initials: B
authors.lastname: Zhang
authors.forename: Fei
authors.initials: F
authors.lastname: Liu
authors.forename: Xin
authors.initials: X
authors.lastname: Wang
authors.forename: Jing
authors.initials: J
authors.lastname: Bai
mesh_terms: D005453:Fluorescence; D007091:Image Processing, Computer-Assisted / Q000379:methods / Q000706:statistics & numerical data; D021621:Imaging, Three-Dimensional / Q000379:methods / Q000706:statistics & numerical data; D016014:Linear Models; D055620:Optical Phenomena; D019047:Phantoms, Imaging; D041622:Tomography, Optical / Q000379:methods* / Q000706:statistics & numerical data