title: Annulus tension of the prolapsed mitral valve corrected by edge-to-edge repair.
abstract: BACKGROUND
  Mitral valve (MV) performance after edge-to-edge repair (ETER) without ring annuloplasty is suboptimal. ETER efficacy needs to be evaluated from annulus tension (AT) of a prolapsed MV corrected by ETER to understand annular dilatation.
  
  
  METHODS
  Ten porcine MVs were harvested and mounted on a MV closure test rig. The MV annulus tissue rested on top of a saddle-shaped plastic ring on which the annulus could slide freely. The annulus was held by strings in the periphery during MV closure under a hydrostatic trans-mitral pressure. String tensions were measured and further divided by string spacing to obtain AT. The MVs were then prolapsed by shifting split papillary muscles to simulate mono-leaflet prolapse due to elongation of chords, which insert into a single leaflet. Last, MV prolapse was corrected by ETER applied in the central leaflet region and AT was measured.
  
  
  RESULTS
  AT in both anterior and posterior leaflet prolapse corrected by ETER was less than that of normal MVs. AT in the anterior leaflet prolapse corrected by ETER was less than that in the posterior leaflet prolapse corrected by ETER.
  
  
  CONCLUSIONS
  ETER does not restore the normal AT and therefore leads potential of annular dilatation. The anterior leaflet prolapse has a greater potential of annular dilatation than the posterior leaflet prolapse after ETER. Annuloplasty is recommended to maintain long-term ETER efficacy.
authors.affiliation: Department of Mechanical Engineering, Texas Tech University, Lubbock, TX 79409, USA.
authors.forename: Shamik
authors.initials: S
authors.lastname: Bhattacharya
authors.forename: Zhaoming
authors.initials: Z
authors.lastname: He
mesh_terms: D000818:Animals; D008943:Mitral Valve / Q000503:physiopathology / Q000601:surgery*; D008944:Mitral Valve Insufficiency / Q000503:physiopathology; D008945:Mitral Valve Prolapse / Q000473:pathology; D008955:Models, Cardiovascular; D013552:Swine