title: Maternal caffeine intake and its effect on pregnancy outcomes.
abstract: OBJECTIVE
  Estimation of the maternal caffeine intake during pregnancy and its influence on pregnancy duration, birthweight and Apgar score of the newborn.
  
  
  METHODS
  The research was conducted on pregnant women who gave birth at the Clinic of Obstetrics, Gynaecology and Oncology, 2nd Faculty of Medicine, Medical University of Warsaw. It covered unifetal pregnancies without diseases (N=509). Research data were collected by direct questionnaire supplemented with data from patients' records. Statistical analysis employed a multivariate logistic regression model and a non-parametric Spearman's rank correlation coefficient.
  
  
  RESULTS
  98.4% of pregnant women consume no more than 300 mg of caffeine per day. Pregnant women who smoke and older women consume more caffeine than non-smokers and younger women [β 1.95 (95% CI: 1.02-2.88)] and [β 0.68 (95% CI: 0.05-1.3)] respectively. There is no association between maternal caffeine intake during pregnancy and the risk of premature birth, the birthweight or the Apgar score of newborns.
  
  
  CONCLUSIONS
  Caffeine intake of no more than 300 mg per day during pregnancy does not affect pregnancy duration and the condition of the newborn.
authors.affiliation: Department of Nutrition and Dietetics with Clinic of Metabolic Diseases and Gastroenterology, National Food and Nutrition Institute, Powsińska St. 61/63, 02-903 Warsaw, Poland. jarosz@izz.waw.pl
authors.forename: Mirosław
authors.initials: M
authors.lastname: Jarosz
authors.forename: Regina
authors.initials: R
authors.lastname: Wierzejska
authors.forename: Magdalena
authors.initials: M
authors.lastname: Siuba
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D001034:Apgar Score; D001628:Beverages / Q000009:adverse effects* / Q000032:analysis; D001724:Birth Weight; D002110:Caffeine / Q000008:administration & dosage / Q000009:adverse effects* / Q000032:analysis; D005260:Female; D047109:Fetal Development; D006785:Hospitals, University; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D039382:Maternal Nutritional Physiological Phenomena; D008499:Medical Records; D011044:Poland / Q000453:epidemiology; D011247:Pregnancy; D011256:Pregnancy Outcome; D047928:Premature Birth / Q000453:epidemiology / Q000209:etiology*; D012189:Retrospective Studies; D012306:Risk; D011795:Surveys and Questionnaires; D055815:Young Adult
chemical_list: D002110:Caffeine