title: [Radiosensitivity assays of normal tissues].
abstract: Radiotherapy allows locoregional control with systemic impact in some indications. Technologic advances decrease the dose received by normal tissues leading to a low crude number of late side effects near to 5%. Intrinsic radiosensitivity are still of interest in this context of high level of technology and optimized treatments. Assays of radiosensitivity are detailed in this article arguing the negative results but also the perspectives.
authors.affiliation: CHU de Montpellier, département de biologie cellulaire, Montpellier, France.
authors.forename: Jérôme
authors.initials: J
authors.lastname: Lacombe
authors.forename: Jérôme
authors.initials: J
authors.lastname: Solassol
authors.forename: Jean-Pierre
authors.initials: JP
authors.lastname: Pouget
authors.forename: Mickael
authors.initials: M
authors.lastname: Coelho
authors.forename: David
authors.initials: D
authors.lastname: Azria
mesh_terms: D017209:Apoptosis / Q000235:genetics; D005347:Fibroblasts / Q000528:radiation effects; D006801:Humans; D008214:Lymphocytes / Q000528:radiation effects; D058958:Organs at Risk / Q000528:radiation effects*; D011237:Predictive Value of Tests; D040901:Proteomics / Q000379:methods; D011832:Radiation Injuries / Q000517:prevention & control*; D011836:Radiation Tolerance / Q000502:physiology*; D014410:Tumor Stem Cell Assay / Q000379:methods