title: A case of thyroid metastasis of nasopharyngeal cancer.
abstract: OBJECTIVE
  Thyroid metastasis from nasopharyngeal carcinoma is a rare occurrence. We report a case of thyroid metastases from nasopharyngeal carcinoma with a review of the literature.
  
  
  METHODS
  In April 2007 a 59-year-old man was diagnosed with nasopharyngeal carcinoma; in October 2009 he underwent a thyroid biopsy that revealed G2 infiltrating spinocellular carcinoma with lymph node involvement. He was treated with chemotherapy and radiotherapy at our institute.
  
  
  RESULTS
  Currently, after 6 cycles of adjuvant chemotherapy with taxotere and gemcitabine, the patient is asymptomatic with stable disease and improved quality of life.
  
  
  CONCLUSIONS
  According to the literature, the treatment choice depends on clinical disease extent. Surgery and/or chemo-radiation therapy must therefore be tailored to the individual patient in order to improve clinical outcome and quality of life.
authors.affiliation: Department of Radiation Oncology, IRCCS - CROB, Rionero in Vulture (PZ), Italy. chiumento.costanza@gmail.com
authors.forename: Costanza
authors.initials: C
authors.lastname: Chiumento
authors.forename: Alba
authors.initials: A
authors.lastname: Fiorentino
authors.forename: Giovanni
authors.initials: G
authors.lastname: Castaldo
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Fusco
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001706:Biopsy; D002277:Carcinoma / Q000175:diagnosis / Q000556:secondary* / Q000628:therapy*; D059186:Chemoradiotherapy, Adjuvant; D003841:Deoxycytidine / Q000008:administration & dosage / Q000031:analogs & derivatives; D000077143:Docetaxel; D004938:Esophageal Neoplasms / Q000556:secondary / Q000628:therapy; D019788:Fluorodeoxyglucose F18; D006801:Humans; D007822:Laryngeal Neoplasms / Q000556:secondary / Q000628:therapy; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D064847:Multimodal Imaging; D000077274:Nasopharyngeal Carcinoma; D009303:Nasopharyngeal Neoplasms / Q000473:pathology* / Q000556:secondary; D049268:Positron-Emission Tomography; D011788:Quality of Life; D011879:Radiotherapy Dosage; D020266:Radiotherapy, Conformal; D043823:Taxoids / Q000008:administration & dosage; D013964:Thyroid Neoplasms / Q000175:diagnosis / Q000556:secondary* / Q000628:therapy*; D014057:Tomography, X-Ray Computed; D014134:Tracheal Neoplasms / Q000556:secondary / Q000628:therapy; D016896:Treatment Outcome; D000093542:Gemcitabine
chemical_list: D043823:Taxoids; D003841:Deoxycytidine; D019788:Fluorodeoxyglucose F18; D000077143:Docetaxel; D000093542:Gemcitabine