title: Clopidogrel (plavix).
abstract: Clopidogrel is an inhibitor of platelet aggregation, indicated for the prevention of ischemic stroke and in-stent thrombosis. However, it has a number of drawbacks, including an increased risk of hemorrhage; a clinical effect that is slow in onset and irreversible; a genetically determined variability in its clinical potency; and interactions with other commonly administered drugs.
authors.affiliation: Department of Radiology, St. Vincent's Hospital Melbourne, Fitzroy, Victoria, Australia. julescomin@gmail.com
authors.forename: J
authors.initials: J
authors.lastname: Comin
authors.forename: D
authors.initials: D
authors.lastname: Kallmes
mesh_terms: D000077144:Clopidogrel; D004305:Dose-Response Relationship, Drug; D006470:Hemorrhage / Q000139:chemically induced* / Q000517:prevention & control*; D006801:Humans; D010975:Platelet Aggregation Inhibitors / Q000008:administration & dosage; D020521:Stroke / Q000517:prevention & control*; D013988:Ticlopidine / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives*
chemical_list: D010975:Platelet Aggregation Inhibitors; D000077144:Clopidogrel; D013988:Ticlopidine