title: Chemical analysis of Penstemon campanulatus (Cav.) Willd.--antimicrobial activities.
abstract: A new iridoid glucoside named 10-isovaleroyl-dihydropenstemide (1), along with nine known compounds was isolated from the aerial part of Penstemon campanulatus (Cav.) Willd. The known compounds include three iridoid glucosides, one phenylpropanoid glucoside, one monoterpene glucoside, one monoterpene lactone and three flavonoids. Their structures were elucidated on the basis of spectral evidence. Additionally four phenolic acids as well as a fatty acid were determined through GC-MS analysis. All isolated compounds and the crude extracts were assayed for their antimicrobial activities against six Gram positive and negative bacteria, as well as against three human pathogenic fungi.
authors.affiliation: Medical University of Lublin, Faculty of Pharmacy, Department of Pharmacognosy with Medicinal Plant Unit, Lublin, Poland.
authors.forename: Sybilla M
authors.initials: SM
authors.lastname: Zajdel
authors.forename: Konstantia
authors.initials: K
authors.lastname: Graikou
authors.forename: Kazimierz
authors.initials: K
authors.lastname: Głowniak
authors.forename: Ioanna
authors.initials: I
authors.lastname: Chinou
mesh_terms: D000890:Anti-Infective Agents / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D002175:Candida / Q000187:drug effects; D005960:Glucosides / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D039823:Iridoids / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D032263:Penstemon / Q000737:chemistry*; D035261:Plant Components, Aerial / Q000737:chemistry; D010936:Plant Extracts / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology
chemical_list: D000890:Anti-Infective Agents; D005960:Glucosides; D039823:Iridoids; D010936:Plant Extracts