title: Schwannoma of the stomach with elevated preoperative serum carbohydrate antigen 19-9: report of a case.
abstract: We herein report a case of a gastric schwannoma with elevated preoperative serum carbohydrate antigen 19-9 (CA19-9) (155.2 U/ml, normal range 0-36.9 U/ml). A 59-year-old Japanese man was admitted to our hospital for treatment of a submucosal tumor of the stomach detected by barium meal, upper gastrointestinal endoscopy, and computed tomography. Endoscopic examination revealed a 3-cm diameter submucosal tumor in the antrum of the stomach, but biopsy of the lesion was unable to confirm the diagnosis. Positron emission tomography to evaluate the malignant potential showed a high uptake of (18)F-fluorodeoxyglucose in the tumor. Laparoscopy-assisted distal gastrectomy was therefore performed. The histopathological findings of the surgical specimen revealed a benign gastric schwannoma, positive for S-100 protein. The postoperative serum CA19-9 levels gradually decreased and normalized. To the best of our knowledge, this is the first report of a gastric schwannoma with elevated serum CA19-9.
authors.affiliation: Department of Surgery, Social Insurance Gunma Chuo General Hospital, 1-7-13 Kouun-cho, Maebashi, Gunma, 371-0025, Japan. mfukuchi@med.gunma-u.ac.jp
authors.forename: Minoru
authors.initials: M
authors.lastname: Fukuchi
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Naitoh
authors.forename: Hisanori
authors.initials: H
authors.lastname: Shoji
authors.forename: Junko
authors.initials: J
authors.lastname: Yamagishi
authors.forename: Masaki
authors.initials: M
authors.lastname: Suzuki
authors.forename: Toru
authors.initials: T
authors.lastname: Yanoma
authors.forename: Shinsuke
authors.initials: S
authors.lastname: Kiriyama
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Kuwano
mesh_terms: D018395:CA-19-9 Antigen / Q000097:blood*; D005743:Gastrectomy; D006801:Humans; D008297:Male; D008875:Middle Aged; D009442:Neurilemmoma / Q000097:blood* / Q000175:diagnosis / Q000601:surgery; D013274:Stomach Neoplasms / Q000097:blood* / Q000175:diagnosis / Q000601:surgery
chemical_list: D018395:CA-19-9 Antigen