title: Regulation of lipid metabolism by palmitoleate and eicosapentaenoic acid (EPA) in mice fed a high-fat diet.
abstract: We investigated whether oral administration of palmitoleate ameliorates disorders of lipid metabolism to clarify the effects of one of the components of fish oil. Lipid levels in the liver and plasma were significantly decreased by palmitoleate and by EPA administration. These results suggest that palmitoleate, in addition to EPA, plays a role in the regulation of lipid metabolism by fish oil.
authors.affiliation: Department of Clinical Dietetics and Human Nutrition, Faculty of Pharmaceutical Sciences, Josai University, Sakada, Saitama, Japan.
authors.forename: Sachiko
authors.initials: S
authors.lastname: Shiba
authors.forename: Nobuyo
authors.initials: N
authors.lastname: Tsunoda
authors.forename: Masaki
authors.initials: M
authors.lastname: Wakutsu
authors.forename: Etsuko
authors.initials: E
authors.lastname: Muraki
authors.forename: Mariko
authors.initials: M
authors.lastname: Sonoda
authors.forename: Phyllis S Y
authors.initials: PS
authors.lastname: Tam
authors.forename: Yoko
authors.initials: Y
authors.lastname: Fujiwara
authors.forename: Shinji
authors.initials: S
authors.lastname: Ikemoto
authors.forename: Keizo
authors.initials: K
authors.lastname: Kasono
mesh_terms: D000284:Administration, Oral; D000818:Animals; D001835:Body Weight / Q000187:drug effects; D059305:Diet, High-Fat / Q000009:adverse effects*; D015118:Eicosapentaenoic Acid / Q000008:administration & dosage / Q000494:pharmacology*; D002149:Energy Intake / Q000187:drug effects; D005229:Fatty Acids, Monounsaturated / Q000008:administration & dosage / Q000494:pharmacology*; D050356:Lipid Metabolism / Q000187:drug effects*; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL
chemical_list: D005229:Fatty Acids, Monounsaturated; C008757:palmitoleic acid; D015118:Eicosapentaenoic Acid