title: Sibutramine (reductil®)-induced cutaneous leukocytoclastic vasculitis: a case report.
abstract: A 24-year old woman presented with hemorrhagic vesicles on her legs. She had taken sibutramine (Reductil®, Abbott Labs., Seoul, South Korea) for 3 months and developed skin lesions the week before. A skin biopsy showed leukocytoclastic vasculitis with conspicuous eosinophilic infiltration of the tissue. These lesions showed improvement after discontinuation of sibutramine. However, 3 months later the skin lesions recurred on other sites on the lower extremities when the patient was rechallenged with the same drug for 2 weeks. Herein, we report the first case of necrotizing vasculitis induced by sibutramine.
authors.affiliation: Department of Dermatology, School of Medicine, Ewha Womans University, Seoul, Korea.
authors.forename: You Jin
authors.initials: YJ
authors.lastname: Ha
authors.forename: You Jin
authors.initials: YJ
authors.lastname: Han
authors.forename: You Won
authors.initials: YW
authors.lastname: Choi
authors.forename: Ki Bum
authors.initials: KB
authors.lastname: Myung
authors.forename: Hae Young
authors.initials: HY
authors.lastname: Choi