title: Successful use of acarbose to manage post-prandial glycaemia in two patients with type 1 diabetes on continuous subcutaneous insulin infusion.
abstract: Post-prandial hyperglycaemia is a particular problem for some patients with diabetes despite administering continuous subcutaneous insulin infusion (CSII) to deliver insulin flexibly. We describe two cases of patients on CSII with persistent post-prandial hyperglycaemia despite varying insulin doses and timing. Treatment with acarbose improved their glycaemic control.
authors.affiliation: University of Cambridge Metabolic Research Laboratories, Department of Medicine, NIHR Cambridge Biomedical Research Centre, IMS-MRL, Box 289 Addenbrookes Hospital, Cambridge CB2 0QQ, UK.
authors.forename: Satya
authors.initials: S
authors.lastname: Dash
authors.forename: Sarah
authors.initials: S
authors.lastname: Crisp
authors.forename: Sara
authors.initials: S
authors.lastname: Hartnell
authors.forename: Sarah
authors.initials: S
authors.lastname: Donald
authors.forename: Katy
authors.initials: K
authors.lastname: Davenport
authors.forename: David
authors.initials: D
authors.lastname: Simmons
authors.forename: Mark
authors.initials: M
authors.lastname: Evans
mesh_terms: D020909:Acarbose / Q000627:therapeutic use*; D000328:Adult; D003922:Diabetes Mellitus, Type 1 / Q000188:drug therapy*; D005260:Female; D065089:Glycoside Hydrolase Inhibitors; D006801:Humans; D006943:Hyperglycemia / Q000188:drug therapy*; D007004:Hypoglycemic Agents / Q000627:therapeutic use; D055104:Infusions, Subcutaneous; D007328:Insulin / Q000627:therapeutic use; D008875:Middle Aged; D019518:Postprandial Period
chemical_list: D065089:Glycoside Hydrolase Inhibitors; D007004:Hypoglycemic Agents; D007328:Insulin; D020909:Acarbose