title: Aromatase inhibitors in the treatment of recurrent ovarian granulosa cell tumors: brief report and review of the literature.
abstract: Granulosa cell tumors are ovarian sex cord stromal cancers that are unique for their indolent nature and late recurrence. Standard treatment regimens utilized include surgery, chemotherapy, and radiotherapy. However, hormonal suppression with aromatase inhibitors, which have shown promising results, may be a viable alternative to these modalities. We present a heavily pre-treated, multi-operated patient who experienced significant tumor shrinkage following treatment with an aromatase inhibitor for her recurrent granulosa cell tumor.
authors.affiliation: Department of Obstetrics and Gynecology Medical Oncology Obstetrics and Gynecology, Division of Gyencologic Oncology, Mayo Clinic, Rochester, Minnesota, USA. alhilli.mariam@mayo.edu
authors.forename: Mariam M
authors.initials: MM
authors.lastname: Alhilli
authors.forename: Harry J
authors.initials: HJ
authors.lastname: Long
authors.forename: Karl C
authors.initials: KC
authors.lastname: Podratz
authors.forename: Jamie N
authors.initials: JN
authors.lastname: Bakkum-Gamez
mesh_terms: D000368:Aged; D047072:Aromatase Inhibitors / Q000627:therapeutic use*; D005260:Female; D006106:Granulosa Cell Tumor / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D009364:Neoplasm Recurrence, Local / Q000188:drug therapy* / Q000473:pathology; D010051:Ovarian Neoplasms / Q000188:drug therapy* / Q000473:pathology; D016896:Treatment Outcome
chemical_list: D047072:Aromatase Inhibitors