title: Corticosteroid therapy for liver abscess in chronic granulomatous disease.
abstract: Liver abscesses in chronic granulomatous disease (CGD) are typically difficult to treat and often require surgery. We describe 9 X-linked CGD patients with staphylococcal liver abscesses refractory to conventional therapy successfully treated with corticosteroids and antibiotics. Corticosteroids may have a role in treatment of Staphylococcus aureus liver abscesses in CGD.
authors.affiliation: Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
authors.forename: Jennifer W
authors.initials: JW
authors.lastname: Leiding
authors.forename: Alexandra F
authors.initials: AF
authors.lastname: Freeman
authors.forename: Beatriz E
authors.initials: BE
authors.lastname: Marciano
authors.forename: Victoria L
authors.initials: VL
authors.lastname: Anderson
authors.forename: Gulbu
authors.initials: G
authors.lastname: Uzel
authors.forename: Harry L
authors.initials: HL
authors.lastname: Malech
authors.forename: SukSee
authors.initials: S
authors.lastname: DeRavin
authors.forename: David
authors.initials: D
authors.lastname: Wilks
authors.forename: Aradhana M
authors.initials: AM
authors.lastname: Venkatesan
authors.forename: Christa S
authors.initials: CS
authors.lastname: Zerbe
authors.forename: Theo
authors.initials: T
authors.lastname: Heller
authors.forename: Steven M
authors.initials: SM
authors.lastname: Holland
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use*; D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D006105:Granulomatous Disease, Chronic / Q000150:complications*; D006801:Humans; D008100:Liver Abscess / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy*; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D000305:Adrenal Cortex Hormones; D000900:Anti-Bacterial Agents; D000893:Anti-Inflammatory Agents