title: The dilemma of diagnosing fever of unknown origin: large arteries vasculitis revealed by 18F-FDG PET/CT imaging. A case report.
abstract: Fever of unknown origin (FUO) is an uncommon disease, and its underlying etiology may include a number causes, i.e., infections, malignancies, autoimmune conditions. Diagnosis is often a difficult task, and usually physician spend time and money in order to define the etiology of FUO. We report a case of patient who presented with FUO and headache, and positron emission tomography (PET) with 2-deoxy-2-[fluorine-18] fluoro-D-glucose (18F-FDG) allowed to reveal the presence of a large vessel vasculitis. 18F-FDG PET may represent an useful tool in patients with FUO, since it can early depict an hypermetabolic activity due to inflammation and so help to achieve a final diagnosis in some cases of FUO.
authors.affiliation: University of Ferrara, Italy.
authors.forename: A
authors.initials: A
authors.lastname: De Giorgi
authors.forename: F
authors.initials: F
authors.lastname: Fabbian
authors.forename: M
authors.initials: M
authors.lastname: Pala
authors.forename: V
authors.initials: V
authors.lastname: Bagnari
authors.forename: R
authors.initials: R
authors.lastname: Tiseo
authors.forename: C
authors.initials: C
authors.lastname: Molino
authors.forename: M R
authors.initials: MR
authors.lastname: Trapassi
authors.forename: A
authors.initials: A
authors.lastname: Boccafogli
authors.forename: F
authors.initials: F
authors.lastname: Portaluppi
authors.forename: N
authors.initials: N
authors.lastname: Prandini
authors.forename: L
authors.initials: L
authors.lastname: Feggi
authors.forename: R
authors.initials: R
authors.lastname: Manfredini
mesh_terms: D005260:Female; D005335:Fever of Unknown Origin / Q000175:diagnosis*; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008875:Middle Aged; D064847:Multimodal Imaging / Q000379:methods*; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals; D014057:Tomography, X-Ray Computed; D014657:Vasculitis / Q000000981:diagnostic imaging*
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18