title: Mortality in people with depressive, anxiety and alcohol use disorders in Finland.
abstract: BACKGROUND
  Mental disorders are associated with increased mortality, but population-based surveys with reliable diagnostic procedures controlling for somatic health status are scarce.
  
  
  OBJECTIVE
  To assess excess mortality associated with depressive, anxiety and alcohol use disorders and the principal causes of death.
  
  
  METHODS
  In a nationally representative sample of Finns aged 30-70 years, psychiatric disorders were diagnosed with the Composite International Diagnostic Interview. After an 8-year follow-up period, vital status and cause of death of each participant was obtained from national registers.
  
  
  RESULTS
  After adjusting for sociodemographic factors, health status and smoking, depressive (hazard ratio (HR) = 1.97) and alcohol use disorders (HR = 1.72) were statistically significantly associated with mortality. Risk of unnatural death was increased among individuals diagnosed with anxiety disorders or alcohol dependence.
  
  
  CONCLUSIONS
  Individuals with depressive and alcohol use disorders have an increased mortality risk comparable with many chronic somatic conditions, that is only partly attributable to differences in sociodemographic, somatic health status and hazardous health behaviour.
authors.affiliation: National Institute for Health and Welfare, Department of Mental Health and Substance Abuse Services, P.O. Box 30, 00271 Helsinki, Finland. niina.markkula@helsinki.fi
authors.forename: Niina
authors.initials: N
authors.lastname: Markkula
authors.forename: Tommi
authors.initials: T
authors.lastname: Härkänen
authors.forename: Jonna
authors.initials: J
authors.lastname: Perälä
authors.forename: Krista
authors.initials: K
authors.lastname: Partti
authors.forename: Sebastián
authors.initials: S
authors.lastname: Peña
authors.forename: Seppo
authors.initials: S
authors.lastname: Koskinen
authors.forename: Jouko
authors.initials: J
authors.lastname: Lönnqvist
authors.forename: Jaana
authors.initials: J
authors.lastname: Suvisaari
authors.forename: Samuli I
authors.initials: SI
authors.lastname: Saarni
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D019973:Alcohol-Related Disorders / Q000401:mortality*; D001008:Anxiety Disorders / Q000401:mortality*; D002423:Cause of Death; D003866:Depressive Disorder / Q000401:mortality*; D005260:Female; D005387:Finland / Q000453:epidemiology; D015438:Health Behavior; D006304:Health Status; D006801:Humans; D007406:Interview, Psychological; D008297:Male; D008875:Middle Aged; D011159:Population Surveillance; D016016:Proportional Hazards Models; D012959:Socioeconomic Factors