title: Evaluation of the VersaTREK system compared to the Bactec MGIT 960 system for first-line drug susceptibility testing of Mycobacterium tuberculosis.
abstract: The aim of this study was to evaluate the reliability of the VersaTREK system for Mycobacterium tuberculosis drug susceptibility testing compared with results obtained with the Bactec MGIT 960 system. A total of 67 strains were evaluated. Overall agreement was at 98.5%. Kappa indexes were 1.0 for isoniazid, rifampin, and ethambutol, 0.937 for pyrazinamide, and 0.907 for streptomycin. The VersaTREK system is validated for M. tuberculosis drug susceptibility testing.
authors.affiliation: Laboratori de Microbiologia, UDIAT-CD, Corporació Sanitària Parc Taulí, Sabadell, Departament de Genètica i Microbiologia, Universitat Autònoma de Barcelona, Barcelona, Spain. mespasa@tauli.cat
authors.forename: M
authors.initials: M
authors.lastname: Espasa
authors.forename: M
authors.initials: M
authors.lastname: Salvadó
authors.forename: E
authors.initials: E
authors.lastname: Vicente
authors.forename: G
authors.initials: G
authors.lastname: Tudó
authors.forename: F
authors.initials: F
authors.lastname: Alcaide
authors.forename: P
authors.initials: P
authors.lastname: Coll
authors.forename: N
authors.initials: N
authors.lastname: Martin-Casabona
authors.forename: M
authors.initials: M
authors.lastname: Torra
authors.forename: D
authors.initials: D
authors.lastname: Fontanals
authors.forename: J
authors.initials: J
authors.lastname: González-Martín
mesh_terms: D000995:Antitubercular Agents / Q000494:pharmacology*; D006801:Humans; D008826:Microbial Sensitivity Tests / Q000379:methods; D009169:Mycobacterium tuberculosis / Q000187:drug effects*
chemical_list: D000995:Antitubercular Agents