title: Design and optimization of photo bioreactor for O2 regulation and control by system dynamics and computer simulation.
abstract: In this paper, a valid kinetic model of photo bioreactor (PBR) used for highly-effective cultivation of blue algae, Spirulina platensis, was developed for fully describing the dynamic characteristics of O(2) concentration, then a closed-loop PBR with Linear-Quadratic Gaussian (LQG) servo controller was established and optimized via digital simulation and dynamic response optimization, and the effectiveness of the closed-loop PBR was further tested and accredited by real-time simulation. The result showed that the closed-loop PBR could regulate and control the O(2) concentration in its gas phase according to the reference with desired dynamic response performance, hence microalgae with unique characteristic could be selected as a powerful tool for O(2) regulation and control whenever O(2) concentration in Bioregenerative Life Support System (BLSS) deviates from the nominal level in emergencies, and greatly enhance safety and reliability of BLSS on space and ground missions.
authors.affiliation: Lab of Environmental Biology and Life Support Technology, School of Biological Science and Medical Engineering, Beihang University, Beijing 100191, China. dwhu@163.com
authors.forename: Dawei
authors.initials: D
authors.lastname: Hu
authors.forename: Ming
authors.initials: M
authors.lastname: Li
authors.forename: Rui
authors.initials: R
authors.lastname: Zhou
authors.forename: Yi
authors.initials: Y
authors.lastname: Sun
mesh_terms: D003198:Computer Simulation; D017076:Computer-Aided Design; D004867:Equipment Design; D019544:Equipment Failure Analysis; D005246:Feedback; D008027:Light; D008954:Models, Biological; D010100:Oxygen / Q000378:metabolism*; D010101:Oxygen Consumption / Q000502:physiology*; D058433:Photobioreactors; D053545:Spirulina / Q000502:physiology* / Q000528:radiation effects
chemical_list: D010100:Oxygen