title: Diagnostic assessment of prosthetic mitral valve thrombosis by real-time three-dimensional transoesophageal echocardiography and successful thrombolytic treatment.
abstract: Prosthetic valve thrombosis (PVT) is a rare but serious complication of valve replacement, most often encountered with mechanical prostheses. The different therapeutic modalities for PVT (fibrinolysis with heparin treatment or surgery) will largely be influenced by the presence of valvular obstruction, the valve location (left or right sided), the patient's clinical status, the existence of and expertise in therapeutic modalities at the institution, and the patient's decision. This report describes a patient with thrombosis of a prosthetic mitral valve, which was successfully treated with recombinant streptokinase in a hospital without cardiac surgery. In this context, the authors present the real-time transoesophageal echocardiographic appearance of this complication, and give a brief review of the literature.
authors.affiliation: Departamento de Cardiologia do Hospital Militar Principal/Instituto Superior, Luanda, Angola. hmorais1@gmail.com
authors.forename: Humberto
authors.initials: H
authors.lastname: Morais
authors.forename: Telmo
authors.initials: T
authors.lastname: Martins
authors.forename: José
authors.initials: J
authors.lastname: Roberto
authors.forename: Fidel
authors.initials: F
authors.lastname: Cáceres-Lóriga
mesh_terms: D000328:Adult; D019560:Echocardiography, Three-Dimensional; D017548:Echocardiography, Transesophageal; D005343:Fibrinolytic Agents / Q000627:therapeutic use; D006349:Heart Valve Diseases / Q000000981:diagnostic imaging / Q000188:drug therapy; D006350:Heart Valve Prosthesis; D006801:Humans; D008297:Male; D008943:Mitral Valve / Q000000981:diagnostic imaging*; D013300:Streptokinase / Q000627:therapeutic use; D013927:Thrombosis / Q000000981:diagnostic imaging* / Q000188:drug therapy
chemical_list: D005343:Fibrinolytic Agents; D013300:Streptokinase