title: Low achieved diastolic pressure in tightly controlled mid-older hypertensive subjects is associated with favorable arterial properties.
abstract: Low diastolic blood pressure (DBP) is commonly seen in well-controlled hypertensive subjects. We evaluated arterial properties in 53 hypertensive subjects with low on-treatment DBP (<70 mm Hg; LODP), 54 subjects with normal BP and spontaneously low DBP (SLDP), and 52 treated hypertensive subjects with DBP ≥70 mm Hg (HNDP). The two measures of large artery rigidity, pulse wave velocity and augmentation index, were similar in LODP and SLDP groups. In contrast, the HNDP group had higher PWV and the lowest large and small artery compliance in comparison with all other groups. Low on-treatment DBP is associated with favorable arterial properties in mid-older hypertensive patients.
authors.affiliation: Institute of Endocrinology, Metabolism and Hypertension, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
authors.forename: Marianna
authors.initials: M
authors.lastname: Yaron
authors.forename: Etty
authors.initials: E
authors.lastname: Osher
authors.forename: Elena
authors.initials: E
authors.lastname: Izkhakov
authors.forename: Joseph B
authors.initials: JB
authors.lastname: Rosenfeld
authors.forename: Naftali
authors.initials: N
authors.lastname: Stern
mesh_terms: D000368:Aged; D001158:Arteries / Q000503:physiopathology*; D001783:Blood Flow Velocity; D001794:Blood Pressure; D005260:Female; D006339:Heart Rate / Q000502:physiology; D006801:Humans; D006973:Hypertension / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged