title: Serological and pathogenic characterization of Erysipelothrix rhusiopathiae isolates from two human cases of endocarditis in Japan.
abstract: We characterized the serological and pathogenic properties of two Erysipelothrix rhusiopathiae isolates from human cases of infective endocarditis in Japan. One isolate was recovered from a fisherman, and was identified as serovar 3, which is known to be prevalent among fish isolates. This strain exhibited high virulence in mice but was avirulent in swine. Another was untypable, and avirulent in both mice and swine. Our results suggest that various serological and athogenical types of E. rhusiopathiae can induce human endocarditis. This is the first report to characterize the pathogenicity of E. rhusiopathiae isolates from human endocarditis.
authors.affiliation: Nippon Veterinary and Life Science University, Musashino, Tokyo, Japan. k-harada@nvku-ac.jp
authors.forename: Kazuki
authors.initials: K
authors.lastname: Harada
authors.forename: Kennichiro
authors.initials: K
authors.lastname: Amano
authors.forename: Shinnich
authors.initials: S
authors.lastname: Akimoto
authors.forename: Kinya
authors.initials: K
authors.lastname: Yamamoto
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Yamamoto
authors.forename: Katsunori
authors.initials: K
authors.lastname: Yanagihara
authors.forename: Shigeru
authors.initials: S
authors.lastname: Kohno
authors.forename: Naoki
authors.initials: N
authors.lastname: Kishida
authors.forename: Toshio
authors.initials: T
authors.lastname: Takahashi
mesh_terms: D000368:Aged; D000818:Animals; D021461:Animals, Outbred Strains; D004697:Endocarditis, Bacterial / Q000175:diagnosis* / Q000382:microbiology*; D004888:Erysipelothrix / Q000302:isolation & purification* / Q000472:pathogenicity; D004889:Erysipelothrix Infections / Q000175:diagnosis* / Q000382:microbiology*; D005260:Female; D005399:Fishes; D006801:Humans; D007564:Japan; D008297:Male; D051379:Mice; D008875:Middle Aged; D009784:Occupational Diseases / Q000175:diagnosis / Q000382:microbiology; D034421:Sus scrofa