title: Total synthesis of penostatin B.
abstract: The first total synthesis of penostatin B has been accomplished by using a highly diastereoselective Pauson-Khand reaction and an efficient relay ring-closing metathesis for the construction of the basic carbon skeleton of the natural product as the key steps.
authors.affiliation: Graduate School of Pharmaceutical Sciences, The University of Tokushima, 1-78-1 Sho-machi, Tokushima 770-8505, Japan.
authors.forename: Kosuke
authors.initials: K
authors.lastname: Fujioka
authors.forename: Hiromasa
authors.initials: H
authors.lastname: Yokoe
authors.forename: Masahiro
authors.initials: M
authors.lastname: Yoshida
authors.forename: Kozo
authors.initials: K
authors.lastname: Shishido
mesh_terms: D001578:Benzopyrans / Q000138:chemical synthesis*; D002244:Carbon / Q000737:chemistry; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D001578:Benzopyrans; C418128:penostatin B; D002244:Carbon