title: Clicking 1,2,4,5-tetrazine and cyclooctynes with tunable reaction rates.
abstract: Substituted tetrazines have been found to undergo facile inverse electron demand Diels-Alder reactions with "tunable" reaction rates.
authors.affiliation: Department of Chemistry, Center for Biotechnology and Drug Design, and Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, Georgia 30302-4098, USA.
authors.forename: Weixuan
authors.initials: W
authors.lastname: Chen
authors.forename: Danzhu
authors.initials: D
authors.lastname: Wang
authors.forename: Chaofeng
authors.initials: C
authors.lastname: Dai
authors.forename: Donald
authors.initials: D
authors.lastname: Hamelberg
authors.forename: Binghe
authors.initials: B
authors.lastname: Wang
mesh_terms: D000480:Alkynes / Q000138:chemical synthesis / Q000737:chemistry*; D003500:Cyclization; D006571:Heterocyclic Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D007700:Kinetics
chemical_list: D000480:Alkynes; D006571:Heterocyclic Compounds