title: Prevalence of Candida species in necrotic pulp with chronic periapical processes.
abstract: The aim of this study was to identify species of the genus Candida in mucosa of oral cavity and in single-rooted teeth with pulp necrosis with chronic endodontic periapical processes, with radiographic images 2+/-4 mm and without clinical symptomatology, in immunocompetent patients. The study included 82 immunocompetent patients of both sexes aged 18-70 years with a clinical dental diagnosis of septic pulp necrosis. Samples were taken from root canals with sterile # 25 paper points and from oral mucosa with a sterile swab. Seven different Candida species were identified (C. albicans, C. dubliniensis, C. guilliermondii, C. krusei, C. parapsilopsis, C. tropicalis and C. glabrata). All of them were present in oral mucosa, while two of them (C. parapsilopsis and C. glabrata) were not identified in the periapical zone of necrotic canals. Considering all the samples isolated from oral mucosa, there was a significantly greater frequency of C. albicans than there was in the periapical zone of necrotic canals.
authors.affiliation: Department of Microbiology and Parasitology, Faculty of Dentistry, University of Buenos Aires, Argentina.
authors.forename: Natalia
authors.initials: N
authors.lastname: Nastri
authors.forename: Maria
authors.initials: M
authors.lastname: Nastri
authors.forename: Virginia
authors.initials: V
authors.lastname: Jewtuchowicz
authors.forename: Maria
authors.initials: M
authors.lastname: Mujica
authors.forename: Cristina
authors.initials: C
authors.lastname: Lovanniti
authors.forename: Ariel
authors.initials: A
authors.lastname: Gualtieri
authors.forename: José
authors.initials: J
authors.lastname: Ponton
authors.forename: Alcira
authors.initials: A
authors.lastname: Rosa
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002175:Candida / Q000302:isolation & purification*; D003790:Dental Pulp Necrosis / Q000382:microbiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010483:Periapical Diseases / Q000382:microbiology*; D055815:Young Adult