title: [Hypoxia is a key factor in the inflammatory milieu of rheumatic diseases].
abstract: Chronic inflammatory diseases are characterized by hypoxia and subsequent cellular adaptation via hypoxia-inducible factor (HIF). Modulation of these adaptation mechanisms provides the basis for ideas on how to improve the effects of known drugs and for the development of novel therapeutic approaches.
authors.affiliation: Medizinische Klinik mit Schwerpunkt Rheumatologie und Klinische Immunologie, Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Deutschland. hahne@drfz.de
authors.forename: M
authors.initials: M
authors.lastname: Hahne
authors.forename: T
authors.initials: T
authors.lastname: Gaber
authors.forename: F
authors.initials: F
authors.lastname: Buttgereit
mesh_terms: D000818:Animals; D015687:Cell Hypoxia / Q000276:immunology*; D006801:Humans; D007113:Immunity, Innate / Q000276:immunology*; D007249:Inflammation / Q000276:immunology*; D007596:Joints / Q000276:immunology*; D018448:Models, Immunological; D012216:Rheumatic Diseases / Q000276:immunology*