title: Rapid radiographic and clinical improvement after treatment of a MET-amplified recurrent glioblastoma with a mesenchymal-epithelial transition inhibitor.
authors.affiliation: Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA 02114, USA. chi.andrew@mgh.harvard.edu
authors.forename: Andrew S
authors.initials: AS
authors.lastname: Chi
authors.forename: Tracy T
authors.initials: TT
authors.lastname: Batchelor
authors.forename: Eunice L
authors.initials: EL
authors.lastname: Kwak
authors.forename: Jeffrey W
authors.initials: JW
authors.lastname: Clark
authors.forename: Daphne L
authors.initials: DL
authors.lastname: Wang
authors.forename: Keith D
authors.initials: KD
authors.lastname: Wilner
authors.forename: David N
authors.initials: DN
authors.lastname: Louis
authors.forename: A John
authors.initials: AJ
authors.lastname: Iafrate
mesh_terms: D001932:Brain Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000235:genetics / Q000473:pathology; D000077547:Crizotinib; D058750:Epithelial-Mesenchymal Transition / Q000187:drug effects*; D005260:Female; D005784:Gene Amplification; D005909:Glioblastoma / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000235:genetics / Q000473:pathology; D006801:Humans; D008875:Middle Aged; D019859:Proto-Oncogene Proteins c-met / Q000235:genetics; D011720:Pyrazoles / Q000627:therapeutic use*; D011725:Pyridines / Q000627:therapeutic use*; D011859:Radiography
chemical_list: D011720:Pyrazoles; D011725:Pyridines; D000077547:Crizotinib; C491743:MET protein, human; D019859:Proto-Oncogene Proteins c-met