title: Recent developments and applications of EMMA in enzymatic and derivatization reactions.
abstract: This review provides systematic coverage of examples in the field of in-capillary electrophorecially mediated microanalysis (EMMA). The recent developments and applications in the time period up to mid 2011 have been described, as well as relevant older papers. The basic principles and modes of in-capillary assays have been demonstrated. An overview is also given of the various injection, separation and detection modes implemented in combination with EMMA. The review is presented in two parts mainly dealing with (i) enzymatic and (ii) derivatization or chemical reactions. Finally, the future trends of CE in performing and monitoring reactions have been drawn.
authors.affiliation: Laboratory for Pharmaceutical Analysis, Faculty of Pharmaceutical Sciences, Katholieke Universiteit Leuven, Belgium.
authors.forename: Xin
authors.initials: X
authors.lastname: Hai
authors.forename: Bao-feng
authors.initials: BF
authors.lastname: Yang
authors.forename: Ann Van
authors.initials: AV
authors.lastname: Schepdael
mesh_terms: D019075:Electrophoresis, Capillary; D057075:Enzyme Assays; D004800:Enzymes, Immobilized; D010575:Pesticides / Q000032:analysis; D011506:Proteins / Q000032:analysis
chemical_list: D004800:Enzymes, Immobilized; D010575:Pesticides; D011506:Proteins