title: Regioselective Pd-catalyzed aerobic aza-Wacker cyclization for preparation of isoindolinones and isoquinolin-1(2H)-ones.
abstract: A switchable regioselective intramolecular aerobic aza-Wacker cyclization catalyzed by palladium is presented. Isoindolinones or isoquinolin-1(2H)-ones could be prepared selectively from the same substrates using different catalysts. The type and steric hindrance of the ligands may be the variables most significant for regiocontrol.
authors.affiliation: School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai 200240, PR China.
authors.forename: Guoqiang
authors.initials: G
authors.lastname: Yang
authors.forename: Wanbin
authors.initials: W
authors.lastname: Zhang
mesh_terms: D001372:Aza Compounds / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D054833:Isoindoles / Q000138:chemical synthesis*; D007546:Isoquinolines / Q000737:chemistry*; D015394:Molecular Structure; D010084:Oxidation-Reduction; D010100:Oxygen / Q000737:chemistry; D010165:Palladium / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D001372:Aza Compounds; D054833:Isoindoles; D007546:Isoquinolines; D010165:Palladium; D010100:Oxygen