title: TORC1 activation and autophagy inhibition: opposing forces in Rheb-driven tumorigenesis.
authors.forename: Jane
authors.initials: J
authors.lastname: Yu
authors.forename: Elizabeth Petri
authors.initials: EP
authors.lastname: Henske
mesh_terms: D001343:Autophagy; D002471:Cell Transformation, Neoplastic; D006801:Humans; D020559:Monomeric GTP-Binding Proteins / Q000502:physiology*; D009479:Neuropeptides / Q000502:physiology*; D000076205:Ras Homolog Enriched in Brain Protein; D014157:Transcription Factors / Q000037:antagonists & inhibitors / Q000378:metabolism* / Q000502:physiology; D015533:Transcriptional Activation; D014402:Tuberous Sclerosis / Q000235:genetics / Q000378:metabolism* / Q000473:pathology; D000077005:Tuberous Sclerosis Complex 2 Protein; D025521:Tumor Suppressor Proteins / Q000235:genetics / Q000502:physiology
chemical_list: C500984:CRTC1 protein, human; D009479:Neuropeptides; C490211:RHEB protein, human; D000076205:Ras Homolog Enriched in Brain Protein; D014157:Transcription Factors; D000077005:Tuberous Sclerosis Complex 2 Protein; D025521:Tumor Suppressor Proteins; D020559:Monomeric GTP-Binding Proteins