title: Mechanical damage to Escherichia coli cells in a model of amino-acid crystal fermentation.
abstract: We investigated the mechanical damage to the Escherichia coli cell caused by polyvinyl chloride particles as a model of amino-acid crystal fermentation. Our results indicated that the glucose-consumption rate and the intracellular ATP concentration temporarily increased by the mechanical damage, and decreased after considerable damage had occurred on cell membrane.
authors.affiliation: Research Institute for Bioscience Products & Fine Chemicals, Ajinomoto Co., Inc., 1–1 Suzuki-cho, Kawasaki-ku, Kawasaki 210–8681, Japan. satoshi_okutani@ajinomoto.com
authors.forename: Satoshi
authors.initials: S
authors.lastname: Okutani
authors.forename: Takayoshi
authors.initials: T
authors.lastname: Iwai
authors.forename: Shintaro
authors.initials: S
authors.lastname: Iwatani
authors.forename: Kazuya
authors.initials: K
authors.lastname: Kondo
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Osumi
authors.forename: Nobuharu
authors.initials: N
authors.lastname: Tsujimoto
authors.forename: Kiyoshi
authors.initials: K
authors.lastname: Matsuno
mesh_terms: D000255:Adenosine Triphosphate / Q000378:metabolism; D000596:Amino Acids / Q000737:chemistry / Q000378:metabolism*; D002462:Cell Membrane / Q000187:drug effects / Q000473:pathology; D004926:Escherichia coli / Q000737:chemistry / Q000378:metabolism*; D005285:Fermentation; D005947:Glucose / Q000378:metabolism; D042541:Intracellular Space / Q000737:chemistry; D011143:Polyvinyl Chloride / Q000633:toxicity; D013314:Stress, Mechanical
chemical_list: D000596:Amino Acids; D000255:Adenosine Triphosphate; D011143:Polyvinyl Chloride; D005947:Glucose