title: Counterpoint: should lactate clearance be substituted for central venous oxygen saturation as goals of early severe sepsis and septic shock therapy? No.
authors.affiliation: Department of Emergency Medicine and Surgery, Henry Ford Hospital, Wayne State University, Detroit, MI. Electronic address: erivers1@hfhs.org.
authors.forename: Emanuel P
authors.initials: EP
authors.lastname: Rivers
authors.affiliation: Department of Medicine, Pulmonary and Critical Care Medicine, California Pacific Medical Center, San Francisco, CA.
authors.forename: Ronald
authors.initials: R
authors.lastname: Elkin
authors.affiliation: Department of Emergency Medicine, University of Kansas Hospital, Kansas City, KS.
authors.forename: Chad M
authors.initials: CM
authors.lastname: Cannon
mesh_terms: D005260:Female; D006801:Humans; D019344:Lactic Acid / Q000378:metabolism*; D008297:Male; D010100:Oxygen / Q000097:blood*; D012151:Resuscitation / Q000379:methods*; D018805:Sepsis / Q000628:therapy*
chemical_list: D019344:Lactic Acid; D010100:Oxygen