title: A quantitative description of the peptide sharing between poliovirus and Homo sapiens.
abstract: In the present study, we analyze the peptide commonality between poliovirus polyprotein and the human proteins. We report on the following findings: (1) the extent of polio peptide overlap on the human proteome is high, and involves the entire viral polyprotein; (2) viral peptide matching affects human proteins linked to fundamental cellular functions. The data may help to further our understanding of the relationships between poliovirus and the human host.
authors.affiliation: Department of Biochemistry and Molecular Biology, University of Bari, Italy.
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Novello
authors.forename: Giovanni
authors.initials: G
authors.lastname: Capone
authors.forename: Candida
authors.initials: C
authors.lastname: Fasano
authors.forename: Simona Lucia
authors.initials: SL
authors.lastname: Bavaro
authors.forename: Anna Nunzia
authors.initials: AN
authors.lastname: Polito
authors.forename: Darja
authors.initials: D
authors.lastname: Kanduc
mesh_terms: D016679:Genome, Viral; D006801:Humans; D010455:Peptides / Q000235:genetics* / Q000276:immunology; D017955:Poliovirus / Q000235:genetics* / Q000276:immunology; D020543:Proteome / Q000235:genetics*; D014764:Viral Proteins / Q000235:genetics* / Q000276:immunology
chemical_list: D010455:Peptides; D020543:Proteome; D014764:Viral Proteins