title: Inorganic-organic magnetic nanocomposites for use in preventive medicine: a rapid and reliable elimination system for cesium.
abstract: OBJECTIVE
  To investigate the potential use of Prussian blue-coated magnetic nanoparticles, termed "Prussian blueberry", to bring about the magnetic elimination of cesium.
  
  
  METHODS
  Prussian blueberry were prepared by a layer-by-layer assembly method. The morphology, structure and physical properties of the Prussian blueberry were investigated as was their ability to magnetically eliminate cesium.
  
  
  RESULTS
  We confirmed that Prussian blueberry were composed of a magnetite nanoparticle-core and a Prussian blue-shell. Under a magnetic field, Prussian blueberry (5 mg) reduced the cesium concentration of seawater (3 ml) from 150 ppm to about 50 ppm; but regular Prussian blue could not magnetically eliminate cesium. Moreover, Prussian blueberry removed a similar proportion of cesium from a larger volume of seawater, and from fetal bovine serum and cow's milk.
  
  
  CONCLUSIONS
  Under a magnetic field, Prussian blueberry was able to rapidly eliminate cesium from seawater and from biological matrices such as serum and milk.
authors.affiliation: Institute of Clinical Medicine and Research, The Jikei University School of Medicine, Kashiwa, Japan. cancer_gene_therapy@ybb.ne.jp
authors.forename: Yoshihisa
authors.initials: Y
authors.lastname: Namiki
authors.forename: Tamami
authors.initials: T
authors.lastname: Namiki
authors.forename: Yukiko
authors.initials: Y
authors.lastname: Ishii
authors.forename: Shigeo
authors.initials: S
authors.lastname: Koido
authors.forename: Yuki
authors.initials: Y
authors.lastname: Nagase
authors.forename: Akihito
authors.initials: A
authors.lastname: Tsubota
authors.forename: Norio
authors.initials: N
authors.lastname: Tada
authors.forename: Yoshitaka
authors.initials: Y
authors.lastname: Kitamoto
mesh_terms: D000818:Animals; D002274:Carcinogens, Environmental / Q000737:chemistry; D002417:Cattle; D002586:Cesium / Q000032:analysis / Q000097:blood / Q000737:chemistry / Q000378:metabolism*; D002588:Cesium Radioisotopes / Q000032:analysis / Q000097:blood / Q000737:chemistry / Q000378:metabolism; D004355:Drug Stability; D005295:Ferrocyanides / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D008280:Magnetics; D008892:Milk / Q000737:chemistry; D053761:Nanocomposites; D011315:Preventive Medicine; D012623:Seawater / Q000737:chemistry; D017550:Spectroscopy, Fourier Transform Infrared; D013499:Surface Properties; D013997:Time Factors; D014961:X-Ray Diffraction
chemical_list: D002274:Carcinogens, Environmental; D002588:Cesium Radioisotopes; D005295:Ferrocyanides; D002586:Cesium; C000170:ferric ferrocyanide