title: Colorimetric logic gates based on aptamer-crosslinked hydrogels.
abstract: We have developed a novel molecular logic gate system based on the incorporation of aptamer-crosslinked hydrogels. Modified gold nanoparticles are used as the output signal, which is visible to the naked eye. This system is designed for AND and OR operations using two chemicals as stimulus inputs.
authors.affiliation: Lab of Biosystem and Microanalysis, State Key Laboratory of Bioreactor Engineering, East China University of Science & Technology, Shanghai 200237, P.R. China.
authors.forename: Bin-Cheng
authors.initials: BC
authors.lastname: Yin
authors.forename: Bang-Ce
authors.initials: BC
authors.lastname: Ye
authors.forename: Hui
authors.initials: H
authors.lastname: Wang
authors.forename: Zhi
authors.initials: Z
authors.lastname: Zhu
authors.forename: Weihong
authors.initials: W
authors.lastname: Tan
mesh_terms: D000255:Adenosine Triphosphate / Q000032:analysis*; D052157:Aptamers, Nucleotide / Q000737:chemistry*; D001483:Base Sequence; D003042:Cocaine / Q000032:analysis*; D003124:Colorimetry / Q000379:methods*; D006046:Gold / Q000737:chemistry; D020100:Hydrogels / Q000737:chemistry*; D053768:Metal Nanoparticles / Q000737:chemistry; D012680:Sensitivity and Specificity; D013056:Spectrophotometry, Ultraviolet / Q000379:methods
chemical_list: D052157:Aptamers, Nucleotide; D020100:Hydrogels; D006046:Gold; D000255:Adenosine Triphosphate; D003042:Cocaine