title: [New innate immunity receptor agonists from sea hydrobionts].
abstract: Scientific data and data obtained by us regarding new innate immunity receptor agonists from sea hydrobionts are presented. Highly efficient and low toxic biologically active substances isolated from sea organisms are inductors of dendritic cells maturation, activate neutrophils, monocytes/macrophages and NK-cells, have an anticomplementary (fucoidans) and pro- and anti-inflammatory effects. Protective properties of biologically active substances are exhibited when various pathogens entering the organism--bacteria, viruses, protozoa, fungi. These substances may become a basis for the creation of new pharmaceutical preparations.
authors.forename: N N
authors.initials: NN
authors.lastname: Besednova
authors.forename: T S
authors.initials: TS
authors.lastname: Zaporozhets
mesh_terms: D000818:Animals; D000890:Anti-Infective Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D059001:Aquatic Organisms / Q000737:chemistry*; D001688:Biological Products / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D002448:Cell Adhesion / Q000187:drug effects; D003713:Dendritic Cells / Q000187:drug effects / Q000276:immunology; D006801:Humans; D007113:Immunity, Innate / Q000187:drug effects*; D007694:Killer Cells, Natural / Q000187:drug effects / Q000276:immunology; D008264:Macrophages / Q000187:drug effects / Q000276:immunology; D009000:Monocytes / Q000187:drug effects / Q000276:immunology; D009504:Neutrophils / Q000187:drug effects / Q000276:immunology; D011971:Receptors, Immunologic / Q000819:agonists*
chemical_list: D000890:Anti-Infective Agents; D001688:Biological Products; D011971:Receptors, Immunologic