title: Influence and critique of CREST and ICSS Trials.
abstract: The principle findings of the Carotid Revascularization Endarterectomy Versus Stenting Trial and the International Carotid Stenting Study are reviewed and discussed. Flaws and possible weaknesses in both trials are highlighted. The possibility that some Carotid Revascularization Endarterectomy Versus Stenting Trial conclusions have been misinterpreted in ways not justified by the trial's data is considered. This possibility may have prompted one conclusion of a recent American Heart Association Guideline on the management of carotid artery disease to be misleading.
authors.affiliation: Division of Vascular Surgery, New York University Medical Center, Bronx, New York 10471, USA. fjvmd@msn.com
authors.forename: Frank J
authors.initials: FJ
authors.lastname: Veith
authors.forename: Kosmas I
authors.initials: KI
authors.lastname: Paraskevas
mesh_terms: D000572:American Heart Association; D001807:Blood Vessel Prosthesis; D016893:Carotid Stenosis / Q000601:surgery*; D016894:Endarterectomy, Carotid / Q000379:methods*; D006801:Humans; D017410:Practice Guidelines as Topic; D016032:Randomized Controlled Trials as Topic; D015203:Reproducibility of Results; D015607:Stents; D014481:United States