title: Clickosomes--using triazole-linked phospholipid connectors to fuse vesicles.
abstract: Two complementary artificial diether phospholipids were synthesized that can undergo a Cu(I)-catalyzed Huisgen-Sharpless click reaction. The resulting lipid can bridge the membranes of large unilamellar vesicles and cause their aggregation and ultimately their fusion.
authors.affiliation: Department of Organic Chemistry, University of Geneva, 1211 Geneva 4, Switzerland.
authors.forename: Frédéric
authors.initials: F
authors.lastname: Loosli
authors.forename: David Alonso
authors.initials: DA
authors.lastname: Doval
authors.forename: David
authors.initials: D
authors.lastname: Grassi
authors.forename: Pierre-Léonard
authors.initials: PL
authors.lastname: Zaffalon
authors.forename: France
authors.initials: F
authors.lastname: Favarger
authors.forename: Andreas
authors.initials: A
authors.lastname: Zumbuehl
mesh_terms: D002384:Catalysis; D057930:Click Chemistry; D003300:Copper / Q000737:chemistry; D015394:Molecular Structure; D010316:Particle Size; D010743:Phospholipids / Q000138:chemical synthesis / Q000737:chemistry*; D013499:Surface Properties; D014230:Triazoles / Q000737:chemistry*
chemical_list: D010743:Phospholipids; D014230:Triazoles; D003300:Copper