title: Short report: Molecular insights for Giardia, Cryptosporidium, and soil-transmitted helminths from a facility-based surveillance system in Guatemala.
abstract: We molecularly characterized samples with Giardia, Cryptosporidium, and soil-transmitted helminths from a facility-based surveillance system for diarrhea in Santa Rosa, Guatemala. The DNA sequence analysis determined the presence of Giardia assemblages A (N = 7) and B (N = 12) and, Cryptosporidium hominis (N = 2) and Cryptosporidium parvum (N = 2), suggestive of different transmission cycles. All 41 samples with soil-transmitted helminths did not have the β-tubulin mutation described for benzimidazole resistance, suggesting potential usefulness in mass drug administration campaigns.
authors.affiliation: Center for Global Health, Division of Parasitic Diseases and Malaria, Centers for Disease Control and Prevention, Atlanta, Georgia 30329, USA. DVelasquez@cdc.gov
authors.forename: Daniel E
authors.initials: DE
authors.lastname: Velasquez
authors.forename: Wences
authors.initials: W
authors.lastname: Arvelo
authors.forename: Vitaliano A
authors.initials: VA
authors.lastname: Cama
authors.forename: Beatriz
authors.initials: B
authors.lastname: López
authors.forename: Lissette
authors.initials: L
authors.lastname: Reyes
authors.forename: Dawn M
authors.initials: DM
authors.lastname: Roellig
authors.forename: Geoffrey D
authors.initials: GD
authors.lastname: Kahn
authors.forename: Kimberly A
authors.initials: KA
authors.lastname: Lindblade
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000818:Animals; D000871:Anthelmintics / Q000627:therapeutic use; D001196:Ascariasis / Q000188:drug therapy / Q000469:parasitology; D017164:Ascaris lumbricoides / Q000235:genetics; D002648:Child; D002675:Child, Preschool; D003457:Cryptosporidiosis / Q000188:drug therapy / Q000469:parasitology; D003458:Cryptosporidium / Q000235:genetics* / Q000502:physiology; D016785:Cryptosporidium parvum / Q000235:genetics / Q000502:physiology; D004351:Drug Resistance / Q000235:genetics; D005872:Giardia / Q000235:genetics* / Q000502:physiology; D005873:Giardiasis / Q000188:drug therapy / Q000469:parasitology; D006166:Guatemala; D006376:Helminths / Q000235:genetics* / Q000502:physiology; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008875:Middle Aged; D060888:Real-Time Polymerase Chain Reaction; D012987:Soil / Q000469:parasitology; D014257:Trichuriasis / Q000188:drug therapy / Q000469:parasitology; D014258:Trichuris / Q000235:genetics / Q000502:physiology; D055815:Young Adult
chemical_list: D000871:Anthelmintics; D012987:Soil