title: Mucosa-associated lymphatic tissue lymphoma of the lower lip in a child.
abstract: Mucosa-associated lymphatic tissue lymphoma of the lip in a child is a very rare clinical entity whose cause is poorly understood. We describe an 11-year-old boy who presented with a 5-month history of an asymptomatic nodule on the lower lip with the clinical appearance of a benign mucocele. After surgical excision of the lower lip lesion, lymphocyte phenotypic analysis and histologic examination of the specimen disclosed an extranodal marginal zone B-cell lymphoma of mucosa-associated lymphatic tissue type of the buccal minor salivary glands. Mucosa-associated lymphatic tissue lymphoma of the lip may clinically resemble a large mucocele. To prevent a delayed detection of lip mucosa-associated lymphatic tissue lymphoma, an incisional biopsy of large mucous cysts of the oral mucosa before marsupialization is recommended.
authors.affiliation: Department of Reconstructive and Diagnostic Surgical Sciences, University of Milan, Milan, Italy. gpbombeccari@libero.it
authors.forename: Gian Paolo
authors.initials: GP
authors.lastname: Bombeccari
authors.forename: Gianpaolo
authors.initials: G
authors.lastname: Guzzi
authors.forename: Diego
authors.initials: D
authors.lastname: Ruffoni
authors.forename: Andrea
authors.initials: A
authors.lastname: Gianatti
authors.forename: Umberto
authors.initials: U
authors.lastname: Mariani
authors.forename: Francesco
authors.initials: F
authors.lastname: Spadari
mesh_terms: D001706:Biopsy; D002648:Child; D003951:Diagnostic Errors; D006801:Humans; D007145:Immunoglobulin kappa-Chains / Q000032:analysis; D016130:Immunophenotyping; D008048:Lip Neoplasms / Q000737:chemistry / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D018442:Lymphoma, B-Cell, Marginal Zone / Q000737:chemistry / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D008297:Male; D009078:Mucocele / Q000175:diagnosis*; D012468:Salivary Gland Neoplasms / Q000737:chemistry / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D012470:Salivary Glands, Minor / Q000473:pathology*
chemical_list: D007145:Immunoglobulin kappa-Chains