title: Medium-term clinical outcomes following surgical repair for vaginal prolapse with tension-free mesh and vaginal support device.
abstract: OBJECTIVE
  This study was designed to evaluate clinical outcomes ≥2 years following surgery with polypropylene mesh and vaginal support device (VSD) in women with vaginal prolapse, in a prospective, multi-center setting.
  
  
  METHODS
  Patients re-consented for this extended follow-up (n = 110), with anatomic evaluation using Pelvic Organ Prolapse Quantification (POP-Q) and validated questionnaires to assess pelvic symptoms and sexual function. Complications were recorded (safety set; n = 121).
  
  
  RESULTS
  Median length of follow-up was 29 months (range 24-34 months). The primary anatomic success, defined as POP-Q 0-I, was 69.1%; however, in 84.5% of the cases, the leading vaginal edge was above the hymen. Pelvic symptoms and sexual function improved significantly from baseline (p < 0.01). Mesh exposure rate was 9.1%. Five percent reported stress urinary incontinence and 3.3% required further prolapse surgery.
  
  
  CONCLUSIONS
  These results indicate this non-anchored mesh repair is a safe and effective treatment for women with symptomatic vaginal prolapse in the medium term.
authors.affiliation: North Hampshire Hospital, Basingstoke, UK.
authors.forename: T
authors.initials: T
authors.lastname: Sayer
authors.forename: J
authors.initials: J
authors.lastname: Lim
authors.forename: J M
authors.initials: JM
authors.lastname: Gauld
authors.forename: P
authors.initials: P
authors.lastname: Hinoul
authors.forename: P
authors.initials: P
authors.lastname: Jones
authors.forename: N
authors.initials: N
authors.lastname: Franco
authors.forename: D
authors.initials: D
authors.lastname: Van Drie
authors.forename: M
authors.initials: M
authors.lastname: Slack
mesh_terms: D000368:Aged; D015331:Cohort Studies; D005260:Female; D005500:Follow-Up Studies; D013509:Gynecologic Surgical Procedures / Q000295:instrumentation / Q000379:methods*; D006801:Humans; D008875:Middle Aged; D011126:Polypropylenes; D053825:Suburethral Slings / Q000009:adverse effects; D013526:Surgical Mesh / Q000009:adverse effects; D011795:Surveys and Questionnaires; D016896:Treatment Outcome; D014596:Uterine Prolapse / Q000601:surgery*
chemical_list: D011126:Polypropylenes