title: Developing the evidence base for the new guidelines for reduction of cardiovascular risk for children by the National Heart, Lung, and Blood Institute.
abstract: In 2006, a process was initiated to develop evidence-based paediatric guidelines directed towards physicians for reduction of cardiovascular risk. In contrast to prior consensus-based guidelines from the National Heart, Lung, and Blood Institute, this process was to be evidenced based. This manuscript describes the process undertaken to write the evidence-based guidelines from the National Heart, Lung, and Blood Institute, beginning with the search for evidence, then the process of review of the evidence, and finally the writing of the final document. This manuscript also provides some thoughts on how this process might be adapted in developing guidelines for caring for patients with congenital cardiac disease.
authors.affiliation: Nemours Cardiac Center, A. I. DuPont Hospital for Children, 1600 Rockland Road, Wilmington, DE 19803, USA. sgidding@nemours.org
authors.forename: Samuel S
authors.initials: SS
authors.lastname: Gidding
mesh_terms: D002318:Cardiovascular Diseases / Q000517:prevention & control*; D002648:Child; D019317:Evidence-Based Medicine / Q000379:methods / Q000592:standards*; D006801:Humans; D054555:National Heart, Lung, and Blood Institute (U.S.); D017410:Practice Guidelines as Topic; D012307:Risk Factors; D014481:United States