title: Lock and key to transcription: σ-DNA interaction.
abstract: How does RNA polymerase recognize a promoter in duplex DNA? How are the DNA strands pried apart to enable RNA synthesis? A crystal structure by Feklistov and Darst unexpectedly reveals that these two processes are interconnected.
authors.affiliation: Department of Structural Biology, Stanford University School of Medicine, Stanford, CA 94305, USA.
authors.forename: Xin
authors.initials: X
authors.lastname: Liu
authors.forename: David A
authors.initials: DA
authors.lastname: Bushnell
authors.forename: Roger D
authors.initials: RD
authors.lastname: Kornberg