title: Haploid embryonic stem cells and the dominance of recessive traits.
abstract: Diploidy, though essential for normal development, is a foil to geneticists. Two recent studies (Elling et al., 2011, this issue of Cell Stem Cell; Leeb and Wutz, 2011, Nature), report the isolation of haploid pluripotent mouse ESCs, thus enabling efficient functional screening for genes involved in diverse cellular and developmental processes.
authors.affiliation: Center for Vertebrate Genomics, Cornell University, Ithaca, NY 14850, USA. jcs92@cornell.edu
authors.forename: John
authors.initials: J
authors.lastname: Schimenti