title: Seven-year clinical performance of CEREC-2 all-ceramic CAD/CAM restorations placed within deeply destroyed teeth.
abstract: OBJECTIVE
  Adhesively luted all-ceramic restorations represent a promising way to preserve and stabilize weakened tooth substance, but little information is published about the clinical performance of extensive all-ceramic restorations.
  
  
  METHODS
  A total of 78 large CEREC 2™ single-tooth all-ceramic restorations had been placed in 35 patients. After 7 years, 59 teeth in 25 patients were reevaluated according to USPHS or modified USPHS criteria regarding aesthetic properties, e.g., "anatomic form," "color match," and "marginal discoloration"; functional properties, e.g., "marginal integrity," wear expressed by the criteria "proximal contact" and "static/dynamic occlusal relationship"; and biological properties, e.g., "tooth vitality" and "secondary caries". Additionally, the "proportion of margin below/above cemento-enamel junction" was included.
  
  
  RESULTS
  Two restorations had failed prior to the 7-year recall, one due to a bulk fracture of the restoration and one due to poor marginal integrity (rated "Charlie") after 4 years. Other six restorations were rated as failure at the 7-year evaluation (three restorations revealed secondary caries, one was bulk fracture of the Cerec 2 restoration, and two failures were related to endodontic problems resulting in extraction or amputation of one root, respectively), resulting in a failure rate of 13.1% after 7 years. A total of 96.4% of the restorations revealed sufficient ratings for esthetic properties "anatomic form," "color match," "marginal discoloration," and "marginal integrity".
  
  
  CONCLUSIONS
  The survival rate of 86.9% at the 7-year recall demonstrates that adhesively luted all-ceramic CAD/CAM-generated restorations are suitable for restoration of extended coronal defects.
  
  
  CONCLUSIONS
  CAD/CAM-generated all-ceramic restorations facilitate the reconstruction of deeply destroyed teeth irrespectively of the location of the cavity margins.
authors.affiliation: Department of Operative Dentistry and Endodontology, Medical Center for Dentistry, University Medical Center Giessen and Marburg, Marburg, Germany. matthias.roggendorf@staff.uni-marburg.de
authors.forename: Matthias J
authors.initials: MJ
authors.lastname: Roggendorf
authors.forename: Bianka
authors.initials: B
authors.lastname: Kunzi
authors.forename: Johannes
authors.initials: J
authors.lastname: Ebert
authors.forename: Hubert C
authors.initials: HC
authors.lastname: Roggendorf
authors.forename: Roland
authors.initials: R
authors.lastname: Frankenberger
authors.forename: Sven M
authors.initials: SM
authors.lastname: Reich
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002516:Ceramics; D017076:Computer-Aided Design; D017267:Dental Prosthesis Design; D019232:Dental Restoration Failure; D019554:Dental Restoration Wear; D003793:Dental Restoration, Permanent / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: C074543:Cerec