title: [The contribution of cancer registries in environmental health studies].
abstract: Cancer incidence is an outcome of interest in studies assessing the health impact of polluted sites, for which an example is represented by SENTIERI Project. Incidence data are characterized by better diagnostic quality and are not influenced by survival factors, furthermore they allow the investigation of high-survival neoplasms (i.e. childhood cancer) and rare malignancies. Furthermore, the study of incidence is more informative than mortality for non-lethal tumours, therefore it represents an advancement in respect to the study of mortality completed in SENTIERI Project. In the last decade in Italy some environmental epidemiology studies used cancer register data, for example the Biancavilla (Sicily) investigation on fluoro-edenite related mesothelioma and the study in an area of Naples Province where hazardous waste was extensively dumped. In this frame, ISS planned some collaborative studies with Siracusa, Mantua and Ferrara cancer Registries, where three major polluted sites are located. Following these pilot studies an ISS-AIRTUM (Italian Association of Cancer Registries) collaborative study has been planned. For a description of SENTIERI, refer to the 2010 supplement of Epidemiology & Prevention, devoted to the Project.
authors.affiliation: Dipartimento ambiente e connessa prevenzione primaria, Istituto superiore di sanità, Rome. pietro.comba@iss.it
authors.forename: P
authors.initials: P
authors.lastname: Comba
authors.forename: L
authors.initials: L
authors.lastname: Fazzo
authors.forename: M
authors.initials: M
authors.lastname: Fusco
authors.forename: M
authors.initials: M
authors.lastname: Benedetti
authors.forename: R
authors.initials: R
authors.lastname: Pirastu
authors.forename: P
authors.initials: P
authors.lastname: Ricci
mesh_terms: D004781:Environmental Exposure; D004782:Environmental Health / Q000379:methods*; D004787:Environmental Pollution / Q000009:adverse effects* / Q000706:statistics & numerical data; D015386:Hazardous Substances / Q000009:adverse effects; D006256:Hazardous Waste / Q000009:adverse effects* / Q000706:statistics & numerical data; D006801:Humans; D015994:Incidence; D007220:Industrial Waste / Q000009:adverse effects* / Q000706:statistics & numerical data; D007558:Italy / Q000453:epidemiology; D015337:Multicenter Studies as Topic; D009369:Neoplasms / Q000453:epidemiology*; D011159:Population Surveillance / Q000379:methods*; D012042:Registries
chemical_list: D015386:Hazardous Substances; D006256:Hazardous Waste; D007220:Industrial Waste