title: Intracorporeal knotting versus metal endoclip application for the closure of the appendiceal stump during laparoscopic appendectomy in uncomplicated appendicitis.
abstract: OBJECTIVE
  The goal of the study was to compare the efficacy of two methods--intracorporeal knotting and metal endoclip application--for closure of the appendiceal stump during laparoscopic appendectomy in a specific group of patients with uncomplicated appendicitis.
  
  
  METHODS
  The patients were randomized into two groups who had their appendiceal stump secured by intracorporeal knotting (Group 1) and metal endoclipping (Group 2). Primary outcome measure was postoperative complications, whereas secondary outcome measures were intraoperative complications, operative time, length of hospital stay, and re-admissions (including rehospitalizations and reoperations).
  
  
  RESULTS
  One hundred seven patients were prospectively recruited in a randomized study between December 2010 and May 2011. Group 1 and Group 2 included 46 and 61 patients, respectively. The rate of postoperative complications in Group 1 and Group 2 was 8.7% (4/46) and 4.9% (3/61) (P>.05). There were no significant differences between the groups in secondary outcome measures except the mean operative time (61.9 minutes versus 46.3 minutes, P=.0008).
  
  
  CONCLUSIONS
  The closure of the appendiceal stump by either intracorporeal knotting or metal endoclipping during laparoscopic appendectomy in uncomplicated appendicitis is safe with comparable morbidity and mortality rates.
authors.affiliation: General Surgery Clinics, Dr. Sadi Konuk Training and Research Hospital, Istanbul, Turkey. gonencmd@hotmail.com
authors.forename: Murat
authors.initials: M
authors.lastname: Gonenc
authors.forename: Eyup
authors.initials: E
authors.lastname: Gemici
authors.forename: Mustafa Uygar
authors.initials: MU
authors.lastname: Kalayci
authors.forename: Mehmet
authors.initials: M
authors.lastname: Karabulut
authors.forename: Ahmet Nuray
authors.initials: AN
authors.lastname: Turhan
authors.forename: Halil
authors.initials: H
authors.lastname: Alis
mesh_terms: D000293:Adolescent; D000328:Adult; D001062:Appendectomy / Q000295:instrumentation*; D001064:Appendicitis / Q000601:surgery*; D005260:Female; D006488:Hemostasis, Surgical / Q000295:instrumentation*; D006801:Humans; D010535:Laparoscopy / Q000295:instrumentation*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000453:epidemiology; D011446:Prospective Studies; D016896:Treatment Outcome