title: Acremostrictin, a highly oxygenated metabolite from the marine fungus Acremonium strictum.
abstract: The novel natural product acremostrictin was isolated from the culture broth of Acremonium strictum, a marine fungus collected from a Choristida sponge off the coast of Korea. Structurally, acremostrictin is a tricyclic lactone of an unprecedented skeletal class based on combined spectroscopic and X-ray crystallographic analyses. The new compound exhibited weak antibacterial and moderate antioxidant activities.
authors.affiliation: Natural Products Research Institute, College of Pharmacy,  Seoul National University , San 56-1, Sillim, Gwanak, Seoul 151-742, Korea.
authors.forename: Elin
authors.initials: E
authors.lastname: Julianti
authors.forename: Hana
authors.initials: H
authors.lastname: Oh
authors.forename: Kyoung Hwa
authors.initials: KH
authors.lastname: Jang
authors.forename: Jae Kyun
authors.initials: JK
authors.lastname: Lee
authors.forename: Sang Kook
authors.initials: SK
authors.lastname: Lee
authors.forename: Dong-Chan
authors.initials: DC
authors.lastname: Oh
authors.forename: Ki-Bong
authors.initials: KB
authors.lastname: Oh
authors.forename: Jongheon
authors.initials: J
authors.lastname: Shin
mesh_terms: D000164:Acremonium / Q000737:chemistry*; D000818:Animals; D000975:Antioxidants / Q000378:metabolism; D001713:Biphenyl Compounds / Q000494:pharmacology; D018360:Crystallography, X-Ray; D006572:Heterocyclic Compounds, Bridged-Ring / Q000737:chemistry / Q000302:isolation & purification*; D007723:Korea; D008386:Marine Biology; D008968:Molecular Conformation; D015394:Molecular Structure; D010851:Picrates / Q000494:pharmacology; D011161:Porifera / Q000382:microbiology
chemical_list: D000975:Antioxidants; D001713:Biphenyl Compounds; D006572:Heterocyclic Compounds, Bridged-Ring; D010851:Picrates; C570343:acremostrictin; C004931:1,1-diphenyl-2-picrylhydrazyl