title: [Kounis syndrome].
abstract: Kounis syndrome was described in 1991 by Kounis and Zavras as the coincidental occurrence of acute coronary syndromes with allergic reactions (anaphylactic or anaphylactoid). Today, allergic angina and allergic myocardial infarction are referred to as Kounis syndrome, and the latter has been reported in association with a variety of drugs, insect stings, food, environmental exposures and medical conditions, among other factors. The incidence is not known, as most of the available information comes from case reports or small case series. In this article, the clinical aspects, diagnosis, pathogenesis, related conditions and therapeutic management of the syndrome are discussed.
authors.affiliation: Servicio de Medicina Intensiva, Hospital Universitario Infanta Leonor, Madrid, España. palomarico@live.com
authors.forename: P
authors.initials: P
authors.lastname: Rico Cepeda
authors.forename: E
authors.initials: E
authors.lastname: Palencia Herrejón
authors.forename: M M
authors.initials: MM
authors.lastname: Rodríguez Aguirregabiria
mesh_terms: D054058:Acute Coronary Syndrome / Q000150:complications* / Q000175:diagnosis / Q000276:immunology / Q000503:physiopathology / Q000628:therapy; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000707:Anaphylaxis / Q000150:complications* / Q000175:diagnosis / Q000276:immunology / Q000503:physiopathology / Q000628:therapy; D000787:Angina Pectoris / Q000209:etiology; D002317:Cardiovascular Agents / Q000627:therapeutic use; D003131:Combined Modality Therapy; D003327:Coronary Disease / Q000150:complications; D003935:Diagnostic Techniques, Cardiovascular; D004342:Drug Hypersensitivity / Q000150:complications; D054855:Drug-Eluting Stents / Q000009:adverse effects; D005440:Fluid Therapy; D005512:Food Hypersensitivity / Q000150:complications; D006633:Histamine Antagonists / Q000627:therapeutic use; D006636:Histamine Release; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000150:complications; D009203:Myocardial Infarction / Q000150:complications; D011379:Prognosis; D013577:Syndrome; D014661:Vasoconstriction
chemical_list: D000305:Adrenal Cortex Hormones; D002317:Cardiovascular Agents; D006633:Histamine Antagonists