title: [Remaxol in pharmacological correction of long-term disorders caused by acute ethylene glycol poisoning].
abstract: The effect of remaxol therapy as a part of the complex acute treatment of ethylene glycol poisoning has been experimentally studied on rats. Special attention was paid to the development of acidosis and hypoxia and a decrease in the functional activity of the urinary and immune systems. It was shown that remaxol is capable of restoring the functional activity of organs and systems susceptible to the toxic effect of ethylene glycol. It is suggested that the therapeutic efficiency of remaxol is based on the normalization of metabolic processes in the cell.
authors.forename: M M
authors.initials: MM
authors.lastname: Liubishin
authors.forename: K V
authors.initials: KV
authors.lastname: Sivak
authors.forename: T N
authors.initials: TN
authors.lastname: Savateeva-Liubimova
mesh_terms: D000138:Acidosis / Q000188:drug therapy* / Q000276:immunology / Q000378:metabolism; D000208:Acute Disease; D000818:Animals; D000931:Antidotes / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D000936:Antigen-Antibody Complex / Q000097:blood; D019855:Ethylene Glycol / Q000506:poisoning*; D000860:Hypoxia / Q000188:drug therapy* / Q000276:immunology / Q000378:metabolism; D056724:Immunity, Humoral / Q000187:drug effects; D007677:Kidney Function Tests; D008297:Male; D010587:Phagocytosis / Q000187:drug effects; D011041:Poisoning / Q000188:drug therapy / Q000276:immunology / Q000378:metabolism; D051381:Rats; D017208:Rats, Wistar; D013386:Succinates / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D013601:T-Lymphocytes / Q000187:drug effects / Q000276:immunology; D013997:Time Factors
chemical_list: D000931:Antidotes; D000936:Antigen-Antibody Complex; C555877:Remaxol; D013386:Succinates; D019855:Ethylene Glycol