title: A double blind controlled trial comparing three treatment  modalities for dentin hypersensitivity.
abstract: OBJECTIVE
  This randomized, double blind, split mouth study was aimed to compare three dentin desensitizing treatment modalities.
  
  
  METHODS
  Two hundred sixty teeth of 25 patients; each having at least 2 hypersensitive teeth in each quadrant, were included. Teeth were randomized to 4 groups: Group A treated with 2% NaF solution, Group B received GLUMA®; an aqueous solution of Hydroxy-Ethyl-Methacrylate and Glutarldehyde, (HEMA-G), Group C received iontophoresis with distilled water (placebo) and Group D was treated with NaF-iontophoresis. Pain response was evaluated on a visual analogue scale (VAS), by using tactile, air blast and cold-water stimuli at 0-day, 15-day, 1-month and 3-months interval.
  
  
  RESULTS
  All treatments were effective in reducing dentinal hypersensitivity significantly, Group D and Group B were more effective than Group A and Group C at all time intervals. Group D and Group B were equally effective in reducing dentinal hypersensitivity at 15-day and 1-month interval but Group D was more effective at 3-months.
  
  
  CONCLUSIONS
  All treatment modalities were more effective in reducing hypersensitivity than placebo. 2% NaF-iontophoresis and HEMA-G were more effective than 2% NaF local application at all time intervals. But at 3-months, 2% NaF-iontophoresis was more effective than HEMA-G, while placebo produced no significant effect in reduction of hypersensitivity.
authors.affiliation: Department of Periodontology, Government Dental College and Hospital Ahmedabad, Gujarat. nilamsahayataperio@gmail.com
authors.forename: Nilam
authors.initials: N
authors.lastname: Brahmbhatt
authors.forename: Neeta
authors.initials: N
authors.lastname: Bhavsar
authors.forename: Vishal
authors.initials: V
authors.lastname: Sahayata
authors.forename: Aneesha
authors.initials: A
authors.lastname: Acharya
authors.forename: Payal
authors.initials: P
authors.lastname: Kshatriya
mesh_terms: D000328:Adult; D057133:Dentin Desensitizing Agents / Q000627:therapeutic use*; D003807:Dentin Sensitivity / Q000188:drug therapy*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D055815:Young Adult
chemical_list: D057133:Dentin Desensitizing Agents