title: Bio-informatics based analysis of genes implicated in alcohol mediated liver injury.
abstract: Alcohol induced liver injury has been studied extensively. Using literature search and bioinformatics tools, the present study characterizes the genes involved in alcohol induced liver injury. The cellular and metabolic processes in which genes involved in alcohol induced liver injury are implicated are also discussed. The genes related to alcohol induced liver injury are also involved in affecting certain molecular functions and metabolism of drugs, besides being associated with diseases. In conclusion, the changes in regulation of genes implicated in alcohol induced liver injury apart from causing alcohol mediated hepatic dysfunction may affect other vital processes in the body.
authors.affiliation: Life Science Division, AU-KBC Research Centre, MIT Campus of Anna University, Chromepet, Chennai, India.
authors.forename: Lakshmanan
authors.initials: L
authors.lastname: Jagannathan
authors.forename: Kavitha
authors.initials: K
authors.lastname: Swaminathan
authors.forename: S Mathan
authors.initials: SM
authors.lastname: Kumar
authors.forename: G Ramesh
authors.initials: GR
authors.lastname: Kumar
authors.forename: Aparajita
authors.initials: A
authors.lastname: Dey
mesh_terms: D000818:Animals; D019295:Computational Biology; D019992:Databases as Topic; D005786:Gene Expression Regulation; D006801:Humans; D008108:Liver Diseases, Alcoholic / Q000235:genetics*; D051379:Mice; D051381:Rats; D015398:Signal Transduction / Q000235:genetics