title: Focal epithelial hyperplasia (Heck's disease) in two Chinese females.
abstract: Focal epithelial hyperplasia, or Heck's disease, is a relatively rare virus-induced benign disease. To the best of the authors' knowledge it has not been reported in an ethnic Chinese population. The authors report two cases of focal epithelial hyperplasia (FEH) in Chinese patients, which were clinically and histologically in accord with FEH. In particular, the lesions in one case were located on the gingival mucosa, which is rarely affected by FEH. DNA extracted from paraffin-embedded specimens from the two patients was tested for the presence of human papilloma virus followed by speciﬁc polymerase chain reaction testing for 16, 18, 13, and 32 subtypes in order to conﬁrm the clinical diagnosis.
authors.affiliation: State Key Laboratory of Oral Diseases, West China College of Stomatology, Sichuan University, China.
authors.forename: N
authors.initials: N
authors.lastname: Liu
authors.forename: Y
authors.initials: Y
authors.lastname: Li
authors.forename: Y
authors.initials: Y
authors.lastname: Zhou
authors.forename: X
authors.initials: X
authors.lastname: Zeng
mesh_terms: D000328:Adult; D052685:Alphapapillomavirus / Q000145:classification / Q000302:isolation & purification*; D002648:Child; D002681:China; D005260:Female; D017573:Focal Epithelial Hyperplasia / Q000473:pathology / Q000821:virology*; D005882:Gingival Diseases / Q000473:pathology / Q000821:virology; D006801:Humans; D008047:Lip Diseases / Q000473:pathology / Q000821:virology; D009061:Mouth Mucosa / Q000473:pathology / Q000821:virology; D030361:Papillomavirus Infections / Q000175:diagnosis* / Q000473:pathology