title: Multimodality treatment approach in children with cerebral arteriovenous malformation--a survey in the Danish population.
abstract: BACKGROUND
  Arteriovenous malformations are not a common disease in childhood. A national survey was conducted to reveal the Danish incidence of the disease, presentation, choice of treatment, and outcome.
  
  
  METHODS
  Forty patients were admitted to any of the five neurosurgical centers during the years 2000-2008. A retrospective survey was conducted using hospital records.
  
  
  RESULTS
  Twenty-three males and 17 females presented with AVM with a mean age of 11.3 (1 month-18 years). The incidence was found to be 0.4/100,000. Early fatal outcome was seen in three patients. Treatment was surgery (12), endovascular (5), radiosurgery (6), or a combination of the above (10). Four patients were treated conservatively. Complications of the treatment were seen in 27%. Occlusion rate was 74%. Good or excellent outcome was seen in 65%.
  
  
  CONCLUSIONS
  A national survey may give a lower rate of success than in the specialized centers accepting patients more eligible for treatment. Still, the low number of children could call for centralization and collaboration in this population.
authors.affiliation: Neurosurgical Department, Rigshospitalet, Copenhagen, Denmark. jane@skjoeth-rasmussen.dk
authors.forename: Jane
authors.initials: J
authors.lastname: Skjøth-Rasmussen
authors.forename: Tina
authors.initials: T
authors.lastname: Obbekjær
authors.forename: Peter
authors.initials: P
authors.lastname: Birkeland
authors.forename: John
authors.initials: J
authors.lastname: Hauerberg
authors.forename: Marianne
authors.initials: M
authors.lastname: Juhler
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003131:Combined Modality Therapy / Q000379:methods; D003625:Data Collection / Q000379:methods; D003718:Denmark / Q000453:epidemiology; D004621:Embolization, Therapeutic / Q000379:methods; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D002538:Intracranial Arteriovenous Malformations / Q000175:diagnosis / Q000453:epidemiology* / Q000628:therapy*; D008297:Male; D016634:Radiosurgery / Q000379:methods; D012189:Retrospective Studies; D016896:Treatment Outcome