title: Upper lip malignant neoplasms. A study of 59 cases.
abstract: OBJECTIVE
  To present the demographic data, clinico-pathologic features and therapeutic outcome of a series of upper lip malignancies.
  
  
  METHODS
  Retrospective study at a single Cancer Institution in Mexico City during a 14-year period.
  
  
  RESULTS
  There were 59 cases, (30 males and 29 females); age range: 14 to 106 years (mean: 73 yr.). Antecedents of ultraviolet light and tobacco exposure were found in 20 (33.9%) and 16 cases (27%) respectively. There were 35 squamous cell carcinomas (59.3%), 19 basal cell carcinomas (32.2%) and one case each (1.7%) of adenocarcinoma NOS, adenoid cystic carcinoma, angiosarcoma, Merkel cell carcinoma and melanoma. There were 14 cases in stage I (23.7%), 14 in stage II (23.7%), 3 in stage III (5.1%) 14 in stage IV (23.7%) and 14 were not classified (23.7%). There were no significant differences with respect to the overall survival curve and the disease-free survival curve among surgical treatment and radiotherapy. In addition, there was not statistically significant difference in the overall survival and disease-free survival among squamous cell carcinoma and basal cell carcinoma cases with respect to the type of treatment.
  
  
  CONCLUSIONS
  Upper lip malignant neoplasms are infrequent lesions. The present series describes the main clinico-pathological features in a hospital-based population in Mexico city and demonstrates some differences with respect to those found in the lower lip.
authors.affiliation: Department of Head and Neck Surgery, Instituto Nacional de Cancerología, México. kuauhyama@yahoo.com.mx
authors.forename: Kuauhyama
authors.initials: K
authors.lastname: Luna-Ortiz
authors.forename: Agustín
authors.initials: A
authors.lastname: Güemes-Meza
authors.forename: Verónica
authors.initials: V
authors.lastname: Villavicencio-Valencia
authors.forename: Adalberto
authors.initials: A
authors.lastname: Mosqueda-Taylor
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008048:Lip Neoplasms / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D055815:Young Adult