title: Colorimetric detection of apoptosis based on caspase-3 activity assay using unmodified gold nanoparticles.
abstract: A new label-free method for the detection of apoptosis was proposed based on colorimetric assay of caspase-3 activity using an unlabeled Asp-Glu-Val-Asp (DEVD)-containing peptide substrate and unmodified gold nanoparticles (AuNPs).
authors.affiliation: State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, PR China.
authors.forename: Yuliang
authors.initials: Y
authors.lastname: Pan
authors.forename: Manli
authors.initials: M
authors.lastname: Guo
authors.forename: Zhou
authors.initials: Z
authors.lastname: Nie
authors.forename: Yan
authors.initials: Y
authors.lastname: Huang
authors.forename: Ying
authors.initials: Y
authors.lastname: Peng
authors.forename: Afang
authors.initials: A
authors.lastname: Liu
authors.forename: Meng
authors.initials: M
authors.lastname: Qing
authors.forename: Shouzhuo
authors.initials: S
authors.lastname: Yao
mesh_terms: D000595:Amino Acid Sequence; D017209:Apoptosis; D053148:Caspase 3 / Q000378:metabolism*; D003124:Colorimetry / Q000379:methods; D006046:Gold / Q000737:chemistry* / Q000378:metabolism; D006801:Humans; D019169:Jurkat Cells; D053758:Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D010455:Peptides / Q000737:chemistry / Q000378:metabolism*
chemical_list: D010455:Peptides; D006046:Gold; D053148:Caspase 3