title: Treatment of fear memories: interactions between extinction and reconsolidation.
abstract: Retrieval labilizes memory traces and these gates two protein synthesis-dependent processes in the brain: extinction, which inhibits further retrieval, and reconsolidation, which may enhance retrieval or change its content. Extinction may itself suffer reconsolidation. Interactions among these processes may be applied to treatments of fear memories, such as those underlying post-traumatic stress disorders.
authors.affiliation: Centro de Memória, Instituto de Pesquisas Biomédicas, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, RS, Brasil.
authors.forename: Natália G
authors.initials: NG
authors.lastname: Fiorenza
authors.forename: Dagieli
authors.initials: D
authors.lastname: Sartor
authors.forename: Jociane C
authors.initials: JC
authors.lastname: Myskiw
authors.forename: Iván
authors.initials: I
authors.lastname: Izquierdo
mesh_terms: D000818:Animals; D001362:Avoidance Learning; D005108:Extinction, Psychological / Q000502:physiology*; D005239:Fear / Q000523:psychology*; D006801:Humans; D008568:Memory / Q000502:physiology*; D051381:Rats; D013313:Stress Disorders, Post-Traumatic / Q000523:psychology / Q000628:therapy*