title: Combining click-multicomponent reaction: one-pot synthesis of triazolyl methoxy-phenyl indazolo[2,1-b]phthalazine-trione derivatives.
abstract: [(1,2,3-Triazol-4-yl)methoxy-phenyl]-2H-indazolo[2,1-b]phthalazine-trione derivatives were synthesized in a simple and efficient method from the one-pot four-component condensation reaction of phthalhydrazide, aromatic propargyloxy aldehydes, active methylene compounds (dimedone and 1,3-cyclohexanedione), and azides in the presence of Cu(OAc)(2)/sodium ascorbate and p-toluenesulfonic acid as catalysts in good to excellent yields.
authors.affiliation: Department of Phytochemistry, Shahid Beheshti University, Tehran, Iran. p-salehi@sbu.ac.ir
authors.forename: Peyman
authors.initials: P
authors.lastname: Salehi
authors.forename: David I
authors.initials: DI
authors.lastname: MaGee
authors.forename: Minoo
authors.initials: M
authors.lastname: Dabiri
authors.forename: Laleh
authors.initials: L
authors.lastname: Torkian
authors.forename: Jordan
authors.initials: J
authors.lastname: Donahue
mesh_terms: D057930:Click Chemistry / Q000379:methods; D020650:Combinatorial Chemistry Techniques; D015394:Molecular Structure; D010793:Phthalazines / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D010793:Phthalazines