title: Cutaneous leiomyosarcoma on the trunk.
abstract: Cutaneous leiomyosarcoma is a relatively uncommon tumor that accounts for 7% of all soft tissue sarcomas. It occurs more frequently in males between 50-70 years and only 10-15% of cases are located on the trunk. Radiotherapy and previous trauma have been implied as risk factors. We report the case of a 57 year-old male with an eight-month history of a hard painless erythematous-violaceous tumor on the presternal region. Histopathology evidenced a malignant spindle cell tumor, "cigar" shaped, with pleomorphic nuclei and a high mitotic index that occupied the entire dermal thickness. Immunohistochemical staining of the tumor cells was positive for smooth muscle actin, desmin and vimentin and negative for S-100 protein and pan-cytokeratin, which supported the diagnosis of dermal leiomyosarcoma. Radical surgery was performed to remove the tumor.
authors.affiliation: Clínica Universitária de Dermatologia, Hospital de Santa Maria, Lisboa, Portugal. marisa.andre@netc.pt
authors.forename: Marisa Carpinteiro
authors.initials: MC
authors.lastname: André
authors.forename: Joana Veiga
authors.initials: JV
authors.lastname: Antunes
authors.forename: Miguel Duarte
authors.initials: MD
authors.lastname: Reis
authors.forename: Paulo Leal
authors.initials: PL
authors.lastname: Filipe
authors.forename: Luís Miguel Soares de
authors.initials: LM
authors.lastname: Almeida
mesh_terms: D006801:Humans; D007890:Leiomyosarcoma / Q000473:pathology* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D012878:Skin Neoplasms / Q000473:pathology* / Q000601:surgery