title: A mouse monoclonal antibody against the γ2 subunit of GABAA receptors.
abstract: A mouse monoclonal antibody directed against the N terminal extracellular epitope of rat γ amino butyric acid (GABA) type-A (GABA(A)R) receptor γ2 subunit was generated. This antibody identified a protein of approximately 42 kDa in Western blot assays using rat and mouse hippocampal proteins. The antibody also detected the expression of γ2 subunit by immunohistochemistry and could immunoprecipitate the γ2 subunit.
authors.affiliation: Department of Neurology, University of Virginia, Health Sciences Center, Charlottesville, 22908, USA.
authors.forename: Suchitra
authors.initials: S
authors.lastname: Joshi
authors.forename: Chengsan
authors.initials: C
authors.lastname: Sun
authors.forename: Jaideep
authors.initials: J
authors.lastname: Kapur
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D058846:Antibodies, Monoclonal, Murine-Derived / Q000276:immunology*; D000918:Antibody Specificity; D000937:Antigen-Antibody Reactions; D015153:Blotting, Western; D057809:HEK293 Cells; D006624:Hippocampus / Q000276:immunology; D006801:Humans; D006825:Hybridomas / Q000276:immunology; D007106:Immune Sera / Q000276:immunology; D007114:Immunization; D007150:Immunohistochemistry; D047468:Immunoprecipitation; D008297:Male; D051379:Mice; D008969:Molecular Sequence Data; D009474:Neurons / Q000276:immunology; D051381:Rats; D011963:Receptors, GABA-A / Q000276:immunology*; D014162:Transfection
chemical_list: D058846:Antibodies, Monoclonal, Murine-Derived; C546281:Gabrg2 protein, rat; D007106:Immune Sera; D011963:Receptors, GABA-A