title: Cushing's syndrome: Stepwise approach to diagnosis.
abstract: The projected prevalence of Cushing's syndrome (CS) inclusive of subclinical cases in the adult population ranges from 0.2-2% and it may no longer be considered as an orphan disease (2-3 cases/million/year). The recognition of CS by physicians is important for early diagnosis and treatment. Late-night salivary cortisol, dexamethasone suppressiontesti, or 24-h urine free cortisol are good screening tests. Positively screened cases need stepwise evaluation by an endocrinologist. This paper discusses the importance of screening for CS and suggests a stepwise diagnostic approach to a case of suspected hypercortisolism.
authors.affiliation: Department of Endocrinology, Seth G. S. Medical College, Parel, Mumbai, Maharashtra, India.
authors.forename: Anurag R
authors.initials: AR
authors.lastname: Lila
authors.forename: Vijaya
authors.initials: V
authors.lastname: Sarathi
authors.forename: Varsha S
authors.initials: VS
authors.lastname: Jagtap
authors.forename: Tushar
authors.initials: T
authors.lastname: Bandgar
authors.forename: Padmavathy
authors.initials: P
authors.lastname: Menon
authors.forename: Nalini S
authors.initials: NS
authors.lastname: Shah