title: Collaboration-based medical knowledge recommendation.
abstract: OBJECTIVE
  Clinicians rely on a large amount of medical knowledge when performing clinical work. In clinical environment, clinical organizations must exploit effective methods of seeking and recommending appropriate medical knowledge in order to help clinicians perform their work.
  
  
  METHODS
  Aiming at supporting medical knowledge search more accurately and realistically, this paper proposes a collaboration-based medical knowledge recommendation approach. In particular, the proposed approach generates clinician trust profile based on the measure of trust factors implicitly from clinicians' past rating behaviors on knowledge items. And then the generated clinician trust profile is incorporated into collaborative filtering techniques to improve the quality of medical knowledge recommendation, to solve the information-overload problem by suggesting knowledge items of interest to clinicians.
  
  
  RESULTS
  Two case studies are conducted at Zhejiang Huzhou Central Hospital of China. One case study is about the drug recommendation hold in the endocrinology department of the hospital. The experimental dataset records 16 clinicians' drug prescribing tracks in six months. This case study shows a proof-of-concept of the proposed approach. The other case study addresses the problem of radiological computed tomography (CT)-scan report recommendation. In particular, 30 pieces of CT-scan examinational reports about cerebral hemorrhage patients are collected from electronic medical record systems of the hospital, and are evaluated and rated by 19 radiologists of the radiology department and 7 clinicians of the neurology department, respectively. This case study provides some confidence the proposed approach will scale up.
  
  
  CONCLUSIONS
  The experimental results show that the proposed approach performs well in recommending medical knowledge items of interest to clinicians, which indicates that the proposed approach is feasible in clinical practice.
authors.affiliation: College of Biomedical Engineering and Instrument Science, Zhejiang University, Zhou Yiqin Building 510, Zheda Road 38#, Hangzhou, Zhejiang 310008, China.
authors.forename: Zhengxing
authors.initials: Z
authors.lastname: Huang
authors.forename: Xudong
authors.initials: X
authors.lastname: Lu
authors.forename: Huilong
authors.initials: H
authors.lastname: Duan
authors.forename: Chenhui
authors.initials: C
authors.lastname: Zhao
mesh_terms: D001185:Artificial Intelligence; D003194:Computer-Assisted Instruction / Q000379:methods*; D003299:Cooperative Behavior; D006801:Humans; D008499:Medical Records; D016347:Medical Records Systems, Computerized / Q000295:instrumentation*; D018794:Problem-Based Learning; D012984:Software; D017749:Total Quality Management / Q000379:methods*