title: Calibrated cusp sizers to facilitate aortic valve repair: development and clinical application.
abstract: Based on the natural mathematical relationships between the components of the human tri-leaflet aortic valve, new calibrated cusp sizers were developed in order to facilitate aortic valve assessment in the operating room and enhance the chance for a perfect restoration of aortic valve competence. These sizers were used clinically to guide the implementation of established aortic valve repair techniques in 10 consecutive patients with severe aortic valve regurgitation. Valve repair was successful in all cases, and at a median follow-up was 5.5 months, aortic valve function remained stable, with aortic regurgitation ≤1+ in every patient and no significant gradient across the aortic valves. This preliminary clinical experience indicates that the calibrated cusp sizers can provide reliable insight into the mechanism of aortic valve insufficiency, and can guide aortic valve repair techniques successfully. We hope that the simplicity and reproducibility of this method would assist in its dissemination and further increase the percentage of aortic valves that are repaired when compared with current practice.
authors.affiliation: Damascus University Cardiac Surgery Hospital, Damascus, Syria. mbizzat@gmail.com
authors.forename: Mohammad Bashar
authors.initials: MB
authors.lastname: Izzat
mesh_terms: D000328:Adult; D001021:Aortic Valve / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D001022:Aortic Valve Insufficiency / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D002138:Calibration; D006348:Cardiac Surgical Procedures / Q000295:instrumentation* / Q000592:standards; D017548:Echocardiography, Transesophageal; D004867:Equipment Design; D005260:Female; D006801:Humans; D008297:Male; D008422:Materials Testing; D008875:Middle Aged; D012720:Severity of Illness Index; D013525:Surgical Instruments / Q000592:standards; D013593:Syria; D013812:Therapeutics; D013997:Time Factors