title: [Granulocyte-colony-stimulating factor (G-CSF)-producing carcinoma of collecting ducts of Bellini: a case report].
abstract: We report a case of granulocyte-colony-stimulating factor (G-CSF)-producing carcinoma of collecting ducts of Bellini. A 62-year-old male was admitted to our hospital with the chief complaint of high grade fever,right flank pain and general malaise. The white blood cell count and serum G-CSF concentration were elevated to 20,100/ μ l and 140 pg/ml,respectively. Enhanced thoracoabdominal computed tomography (CT) showed a right renal malignant tumor without capsule,para-aortic lymph node metastases and lung metastases. CT-guided right renal biopsy was performed. The histological diagnosis was GCSF- producing carcinoma of collecting ducts of Bellini. The chemotherapy (gemcitabine and cisplatin) and the molecular target therapy (sunitinib) were administerd but the primary lesion and metastases was progressive and serum G-CSF concentration was elevated to 229 pg/ml. He died 3 months after diagnosis.
authors.affiliation: The Department of Urology, Kobe City Medical Center General Hospital.
authors.forename: Takayuki
authors.initials: T
authors.lastname: Sumiyoshi
authors.forename: Keiyu
authors.initials: K
authors.lastname: Matsumoto
authors.forename: Noriaki
authors.initials: N
authors.lastname: Utsunomiya
authors.forename: Takehiko
authors.initials: T
authors.lastname: Segawa
authors.forename: Koei
authors.initials: K
authors.lastname: Muguruma
authors.forename: Yukihiro
authors.initials: Y
authors.lastname: Imai
authors.forename: Mutsushi
authors.initials: M
authors.lastname: Kawakita
mesh_terms: D002277:Carcinoma / Q000473:pathology*; D016179:Granulocyte Colony-Stimulating Factor / Q000096:biosynthesis*; D006801:Humans; D007680:Kidney Neoplasms / Q000473:pathology*; D007685:Kidney Tubules, Collecting; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis
chemical_list: D016179:Granulocyte Colony-Stimulating Factor