title: [Efficacy of tribendimdine in treatment of hookworm infection].
abstract: OBJECTIVE
  To study the efficacy of tribendimdine in the treatment of hookworm infection.
  
  
  METHODS
  Forty-seven cases of hookworm infection detected in a cross-sectional study were selected and randomly divided into two groups, one was experimental group (23 cases) treated with tribendimdine and the other was control group (24 cases) treated with albendazole. The negative conversion rates and the incidence rates of adverse effects in the two groups were observed and compared.
  
  
  RESULTS
  The negative conversion rates and the incidence rates of adverse effects of the two groups were 95.65% and 95.83%, 8.70% and 8.33%, respectively, there were no statistical differences (both P values > 0.05).
  
  
  CONCLUSIONS
  The efficacy of tribendimdine in the treatment of hookworm infection is similar to albendazole.
authors.affiliation: National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, WHO Collaborating Center for Malaria, Schistosomiasis and Filariasis, Key Laboratory of Parasite and Vector Biology, Ministry of Health,Shanghai 200025, China.
authors.forename: Li-Guang
authors.initials: LG
authors.lastname: Tian
authors.forename: Guo-Jin
authors.initials: GJ
authors.lastname: Cheng
authors.forename: Feng-Feng
authors.initials: FF
authors.lastname: Wang
authors.forename: Jian
authors.initials: J
authors.lastname: Guo
authors.forename: Yu-Chun
authors.initials: YC
authors.lastname: Cai
authors.forename: Tian-Ping
authors.initials: TP
authors.lastname: Wang
authors.forename: Jia-Xu
authors.initials: JX
authors.lastname: Chen
authors.forename: Xiao-Nong
authors.initials: XN
authors.lastname: Zhou
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D015766:Albendazole / Q000627:therapeutic use; D000723:Ancylostomatoidea / Q000187:drug effects* / Q000502:physiology; D000818:Animals; D000871:Anthelmintics / Q000627:therapeutic use*; D002648:Child; D005260:Female; D006725:Hookworm Infections / Q000188:drug therapy* / Q000469:parasitology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010655:Phenylenediamines / Q000627:therapeutic use*; D055815:Young Adult
chemical_list: D000871:Anthelmintics; D010655:Phenylenediamines; C056017:tribendimidine; D015766:Albendazole