title: Auxin biosynthesis: a simple two-step pathway converts tryptophan to indole-3-acetic acid in plants.
abstract: Indole-3-acetic acid (IAA), the main naturally occurring auxin, is essential for almost every aspect of plant growth and development. However, only recently have studies finally established the first complete auxin biosynthesis pathway that converts tryptophan (Trp) to IAA in plants. Trp is first converted to indole-3-pyruvate (IPA) by the TAA family of amino transferases and subsequently IAA is produced from IPA by the YUC family of flavin monooxygenases. The two-step conversion of Trp to IAA is the main auxin biosynthesis pathway that plays an essential role in many developmental processes.
authors.affiliation: Section of Cell and Developmental Biology, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0116, USA. yundezhao@ucsd.edu
authors.forename: Yunde
authors.initials: Y
authors.lastname: Zhao
mesh_terms: D053898:Biosynthetic Pathways; D007210:Indoleacetic Acids / Q000737:chemistry / Q000378:metabolism*; D010105:Oxygenases / Q000378:metabolism; D010944:Plants / Q000378:metabolism*; D000637:Transaminases / Q000378:metabolism; D014364:Tryptophan / Q000737:chemistry / Q000378:metabolism*
chemical_list: D007210:Indoleacetic Acids; C030737:indoleacetic acid; D014364:Tryptophan; D010105:Oxygenases; D000637:Transaminases