title: Cognitive dysfunction and antiphospholipid antibodies.
abstract: Antiphospholipid syndrome (APS) is a multisystem prothrombotic condition, however, in recent years, its inflammatory nature has been studied extensively. Cerebral involvement is commonly observed in APS and results in different clinical manifestations. However, most of the studies include secondary APS. In this article, we review the prevalence, clinical characteristics, and physiopathology of cognitive impairment in patients with primary APS.
authors.affiliation: Department of Medicine, Faculty of Medical Science, State University of Campinas, Campinas, Brazil.
authors.forename: Simone
authors.initials: S
authors.lastname: Appenzeller
authors.forename: Aline Tamires
authors.initials: AT
authors.lastname: Lapa
authors.forename: Jozélio Freire
authors.initials: JF
authors.lastname: de Carvalho
authors.forename: Fernando Augusto
authors.initials: FA
authors.lastname: Peres
authors.forename: Yehuda
authors.initials: Y
authors.lastname: Shoenfeld
mesh_terms: D017152:Antibodies, Antiphospholipid / Q000097:blood; D016736:Antiphospholipid Syndrome / Q000150:complications*; D003072:Cognition Disorders / Q000209:etiology*; D006801:Humans; D015995:Prevalence
chemical_list: D017152:Antibodies, Antiphospholipid