title: Pulmonary involvement of Brucellosis: a report of six cases.
abstract: BACKGROUND
  Pulmonary involvement of brucellosis rarely occurs due to inhalation of infected aerosol or hematogenous overspreading.
  
  
  OBJECTIVE
  The study aimed to reveal the pulmonary manifestations of brucellosis that occur rarely in Brucella infections in the context of six cases in this report.
  
  
  METHODS
  Between 1998-2008, 82 patients with brucellosis treated and followed up at infectious diseases clinic have been retrospectively studied in relation to their clinical and laboratory findings and treatment results.
  
  
  RESULTS
  Patients' (n=6) age ranged from 48 to 59 years and they showed equal gender distribution. All patients presented with fever and cough. Radiological examination showed pneumonic patches and consolidation in two cases, bilateral glass round opacity in four cases, perivascular and peribronchial thickness increase in two cases, pleural effusion in two cases, sentri-acinar emphysematous images in one patient, and athelectasis in one patient. Blood cultures of three patients grew Brucella spp. All patients responded to treatment containing doxycycline, rifampicin and streptomycin (for only one patient) within seven to 10 days and were treated for six weeks except for one patient for who was treated eight weeks due to hepatosplenic brucellosis.
  
  
  CONCLUSIONS
  Pulmonary involvement of brucellosis has good prognosis with combined antimicrobial therapy.
authors.affiliation: Department of Infectious Diseases and Clinical Microbiology, Ministry of Health, Okmeydaný Training and Research Hospital, Istanbul, Turkey.
authors.forename: F
authors.initials: F
authors.lastname: Simsek
authors.forename: M T
authors.initials: MT
authors.lastname: Yildirmak
authors.forename: H
authors.initials: H
authors.lastname: Gedik
authors.forename: A
authors.initials: A
authors.lastname: Kantürk
authors.forename: E N
authors.initials: EN
authors.lastname: Iris
mesh_terms: D000890:Anti-Infective Agents / Q000627:therapeutic use*; D002006:Brucellosis / Q000188:drug therapy / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008171:Lung Diseases / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed
chemical_list: D000890:Anti-Infective Agents