title: Alkaloids and sesquiterpenes from the South China Sea gorgonian Echinogorgia pseudossapo.
abstract: Five zoanthoxanthin alkaloids (1-5) and four sesquiterpenes (6-9) were isolated from the South China Sea gorgonian Echinogorgia pseudossapo. Their structures were determined on the bases of extensive spectroscopic analyses, including 1D and 2D NMR data. Among them, pseudozoanthoxanthins III and IV (1-2), 8-hydroxy-6β-methoxy-14- oxooplop-6,12-olide (6) and 3β-methoxyguaian-10(14)-en-2β-ol (7) were new, 1 and 3 showed mild anti-HSV-1 activity, and 7 showed significant antilarval activity towards Balanus amphitrite larvae.
authors.affiliation: Key Laboratory of Marine Bio-resources Sustainable Utilization, Guangdong Key Laboratory of Marine Materia Medica, RNAM Center for Marine Microbiology, South China Sea Institute of Oceanology, The Chinese Academy of Sciences, 164 West Xingang Road, Guangzhou 510301, China.
authors.forename: Cheng-Hai
authors.initials: CH
authors.lastname: Gao
authors.affiliation: Guangzhou Jinan Biomedicine Research and Development Center, Guangzhou 510632, China.
authors.forename: Yi-Fei
authors.initials: YF
authors.lastname: Wang
authors.affiliation: Guangzhou Jinan Biomedicine Research and Development Center, Guangzhou 510632, China.
authors.forename: Shen
authors.initials: S
authors.lastname: Li
authors.affiliation: Department of Biology, Hong Kong University of Science and Technology, Clearwater Bay, Kowloon, Hong Kong, China.
authors.forename: Pei-Yuan
authors.initials: PY
authors.lastname: Qian
authors.affiliation: Key Laboratory of Marine Bio-resources Sustainable Utilization, Guangdong Key Laboratory of Marine Materia Medica, RNAM Center for Marine Microbiology, South China Sea Institute of Oceanology, The Chinese Academy of Sciences, 164 West Xingang Road, Guangzhou 510301, China.
authors.forename: Shu-Hua
authors.initials: SH
authors.lastname: Qi
mesh_terms: D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D000818:Animals; D037421:Anthozoa / Q000737:chemistry*; D000998:Antiviral Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D002681:China; D002522:Chlorocebus aethiops; D007093:Imidazoles / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D007814:Larva / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D009792:Oceans and Seas; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D001468:Thoracica / Q000187:drug effects; D014709:Vero Cells
chemical_list: D000470:Alkaloids; D000998:Antiviral Agents; D007093:Imidazoles; D012717:Sesquiterpenes; C009702:zoanthoxantin