title: [Fungal infections in the intensive care unit].
abstract: Invasive infections through to sepsis caused by fungi in intensive care units have increased markedly in the past few years. In the mean time almost every tenth case of sepsis in the intensive care unit is the result of an invasive fungal infection. Not only hemato-oncological or organ-transplanted patients are affected but increasingly also those patients who have been under intensive care for a considerable time and who exhibit particular risk factors. The lethality among the afflicted patients is high. The diagnosis of fungal infections is still difficult; unambiguous, highly sensitive and specific test procedures are still lacking. The decision for therapy must often be made empirically and as early as possible. In the past few years newly developed antimycotic agents have opened up new options for therapy.
authors.affiliation: Klinik für Anästhesie und Intensivtherapie, Universitätsklinikum Gießen und Marburg GmbH, Standort Marburg.
authors.forename: Klaus
authors.initials: K
authors.lastname: Kerwat
authors.forename: Caroline
authors.initials: C
authors.lastname: Rolfes
authors.forename: Hinnerk
authors.initials: H
authors.lastname: Wulf
mesh_terms: D000935:Antifungal Agents; D003422:Critical Care / Q000379:methods*; D003428:Cross Infection / Q000175:diagnosis* / Q000188:drug therapy*; D006801:Humans; D016533:Mycological Typing Techniques / Q000379:methods*; D009181:Mycoses / Q000175:diagnosis* / Q000188:drug therapy*
chemical_list: D000935:Antifungal Agents