title: Improvement of neuronal cell adhesiveness on parylene with oxygen plasma treatment.
abstract: We improved adhesiveness of a neuron-like cell, PC12, on a Parylene-C surface by O(2) plasma treatment which changes the surface from hydrophobic to hydrophilic. Neural cell adhesiveness on the plasma-treated Parylene-C was more than twenty times better compared to non-treated Parylene-C and it was close to that on a conventional polystyrene tissue-culture dish.
authors.affiliation: Graduate School of Bio-Application and System Engineering, Tokyo University of Agriculture and Technology, Tokyo 184-8588, Japan.
authors.forename: Takayuki
authors.initials: T
authors.lastname: Hoshino
authors.forename: Itsuro
authors.initials: I
authors.lastname: Saito
authors.forename: Reo
authors.initials: R
authors.lastname: Kometani
authors.forename: Kazuyuki
authors.initials: K
authors.lastname: Samejima
authors.forename: Shinji
authors.initials: S
authors.lastname: Matsui
authors.forename: Takafumi
authors.initials: T
authors.lastname: Suzuki
authors.forename: Kunihiko
authors.initials: K
authors.lastname: Mabuchi
authors.forename: Yasuhiro X
authors.initials: YX
authors.lastname: Kato
mesh_terms: D001672:Biocompatible Materials / Q000737:chemistry; D002448:Cell Adhesion; D006801:Humans; D057927:Hydrophobic and Hydrophilic Interactions; D009474:Neurons / Q000166:cytology*; D010100:Oxygen / Q000737:chemistry*; D011108:Polymers / Q000737:chemistry*; D011137:Polystyrenes / Q000737:chemistry; D013499:Surface Properties; D046509:Tissue Culture Techniques / Q000379:methods*; D014992:Xylenes / Q000737:chemistry*
chemical_list: D001672:Biocompatible Materials; D011108:Polymers; D011137:Polystyrenes; D014992:Xylenes; C011055:parylene; D010100:Oxygen