title: New triterpenoids from the leaves of Cyclocarya paliurus.
abstract: Six new triterpenoids including four new secodammarane triterpenoid glycosides (1-4), an epoxydammarane triterpenoid glycoside (5), and a new secodammarane triterpenoid (6) were isolated from the ethanolic extract of the leaves of Cyclocarya paliurus. The structures of these compounds were elucidated by spectroscopic analysis methods. Compounds 1-6 were evaluated for their inhibitory activities against α-glucosidase, lipase, DPP-IV, and aldose reductase.
authors.affiliation: State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, P. R. China. lishuai@imm.ac.cn
authors.forename: Shuai
authors.initials: S
authors.lastname: Li
authors.forename: Baosong
authors.initials: B
authors.lastname: Cui
authors.forename: Quan
authors.initials: Q
authors.lastname: Liu
authors.forename: Li
authors.initials: L
authors.lastname: Tang
authors.forename: Yongchun
authors.initials: Y
authors.lastname: Yang
authors.forename: Xiangju
authors.initials: X
authors.lastname: Jin
authors.forename: Zhufang
authors.initials: Z
authors.lastname: Shen
mesh_terms: D000449:Aldehyde Reductase / Q000037:antagonists & inhibitors / Q000378:metabolism; D002681:China; D004791:Enzyme Inhibitors / Q000302:isolation & purification / Q000494:pharmacology; D065089:Glycoside Hydrolase Inhibitors; D006027:Glycosides / Q000302:isolation & purification / Q000494:pharmacology; D029525:Juglandaceae / Q000737:chemistry*; D008049:Lipase / Q000037:antagonists & inhibitors / Q000378:metabolism; D010936:Plant Extracts / Q000302:isolation & purification / Q000494:pharmacology; D018515:Plant Leaves / Q000737:chemistry; D014315:Triterpenes / Q000302:isolation & purification* / Q000494:pharmacology*; D000520:alpha-Glucosidases / Q000378:metabolism
chemical_list: D004791:Enzyme Inhibitors; D065089:Glycoside Hydrolase Inhibitors; D006027:Glycosides; D010936:Plant Extracts; D014315:Triterpenes; D000449:Aldehyde Reductase; D008049:Lipase; D000520:alpha-Glucosidases