title: Number of graphene layers exhibiting an influence on oxidation of DNA bases: analytical parameters.
abstract: This article investigates the analytical performance of double-, few- and multi-layer graphene upon oxidation of adenine and guanine. We observed that the sensitivity of differential pulse voltammetric response of guanine and adenine is significantly higher at few-layer graphene surface than single-layer graphene. We use glassy carbon electrode as substrate coated with graphenes. Our findings shall have profound influence on construction of graphene based genosensors.
authors.affiliation: Division of Chemistry & Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore, Singapore.
authors.forename: Madeline Shuhua
authors.initials: MS
authors.lastname: Goh
authors.forename: Martin
authors.initials: M
authors.lastname: Pumera
mesh_terms: D000225:Adenine / Q000737:chemistry*; D015374:Biosensing Techniques; D004247:DNA / Q000737:chemistry*; D004563:Electrochemistry; D004566:Electrodes; D006108:Graphite / Q000737:chemistry*; D006147:Guanine / Q000737:chemistry*; D010084:Oxidation-Reduction
chemical_list: D006147:Guanine; D006108:Graphite; D004247:DNA; D000225:Adenine