title: Management of multiple drug allergies in children.
abstract: Children with multiple drug allergies are likely to require treatment with one or more of the drugs to which they may have had a reaction, when there is no alternate effective drug available. Detailed review of their history and/or use of appropriate diagnostic studies will help determine the potential safety of readministering the desired drug as well as the method for its readministration, most likely in the form of a drug challenge or desensitization. A practical approach to the diagnosis and treatment of children with multiple drug allergies is described in this review.
authors.affiliation: Children's Hospital Boston, Division of Immunology, Harvard Medical School, Boston, MA 02115, USA. anahita.dioun@childrens.harvard.edu
authors.forename: Anahita Falakshahi
authors.initials: AF
authors.lastname: Dioun
mesh_terms: D002648:Child; D003888:Desensitization, Immunologic / Q000379:methods; D004342:Drug Hypersensitivity / Q000175:diagnosis* / Q000628:therapy*; D004361:Drug Tolerance; D006801:Humans; D008487:Medical History Taking; D010808:Physical Examination; D012882:Skin Tests