title: [Primary hyperparathyroidism in the dog. Diagnosis, therapy and postoperative management in 19 dogs].
abstract: OBJECTIVE
  Retrospective evaluation of diagnosis and outcome in 20 dogs with primary hyperparathyroidism.
  
  
  METHODS
  In 20 dogs primary hyperparathyroidism was diagnosed and 19 patients were treated via parathyroidectomy, 10 additionally with partial thyroidectomy. Medical records of the dogs were reviewed for signalment, clinical features, laboratory findings and results of histopathologic examination. In some cases postsurgical rehabilitation of calcium metabolism required substitution with calcium and vitamin D preparations.
  
  
  RESULTS
  Mean age of the dogs was 11.5 years. The most common clinical signs comprised polydipsia, polyuria, reduced activity, and stiff gait. Laboratory findings were moderate to extensive hypercalcaemia, low or low-normal serum phosphorus concentrations and normal or increased serum parathyroid hormone concentrations. None of the dogs had an elevated parathyroid hormone-related polypeptide level. Histological examination revealed 11 adenomas, six carcinomas and two glandular hyperplasias. Postsurgical management of calcium homeostasis was challenging in some cases.
  
  
  CONCLUSIONS
  Tumours of the parathyroid gland can be easily treated by parathyroidectomy and usually have a good prognosis.
  
  
  CONCLUSIONS
  With careful interpretation of laboratory findings of a patient presenting with hypercalcaemia and ruling out other causes of hypercalcaemia diagnosis of primary hyperparathyroidism can be easily achieved and successfully treated byparathyroidectomy.
authors.affiliation: Tierklinik Hofheim, Im Langgewann 9, 65719 Hofheim am Taunus. info@tierklinik-hofheim.de
authors.forename: K
authors.initials: K
authors.lastname: Jores
authors.forename: M
authors.initials: M
authors.lastname: Kessler
mesh_terms: D000818:Animals; D002118:Calcium / Q000008:administration & dosage / Q000378:metabolism; D004283:Dog Diseases / Q000175:diagnosis* / Q000601:surgery / Q000628:therapy*; D004285:Dogs; D005260:Female; D006934:Hypercalcemia / Q000209:etiology / Q000662:veterinary; D049950:Hyperparathyroidism, Primary / Q000175:diagnosis / Q000628:therapy / Q000662:veterinary*; D008297:Male; D010282:Parathyroid Neoplasms / Q000150:complications / Q000601:surgery / Q000662:veterinary; D016105:Parathyroidectomy / Q000662:veterinary; D011182:Postoperative Care / Q000662:veterinary*; D011183:Postoperative Complications / Q000628:therapy / Q000662:veterinary*; D011379:Prognosis; D012189:Retrospective Studies; D013965:Thyroidectomy / Q000662:veterinary; D016896:Treatment Outcome; D014807:Vitamin D / Q000008:administration & dosage; D014815:Vitamins / Q000008:administration & dosage
chemical_list: D014815:Vitamins; D014807:Vitamin D; D002118:Calcium