title: [The extent of coronary stenosis and the level of antibodies to atherogenic lipoproteins in patients with coronary heart disease].
abstract: OBJECTIVE
  To study association between the level of antibodies to oxidized low-density lipoproteins (anti-OLDL) and the extent of coronary stenosis (CS) in patients with coronary heart disease (CHD).
  
  
  METHODS
  Sixty CHD patients were examined for titer of anti-OLDL, levels of total cholesterol (TC), LDLP cholesterol, HDLP cholesterol, triglycerides. Selective coronarography (SC) was made on demand.
  
  
  RESULTS
  Elevated titer of anti-OLDL was found only in 12 examinees. It was significantly lower in CHD women than in men. No significant differences by anti-OLDL were found in CHD patients with and without significant risk factors. SC registered in all CHD examinees local stenosis of different severity. Stenosis in 3 coronary arteries was detected in 31 cases, in 2 coronary arteries--in 14, in 1 coronary artery--in 15 patients, most frequently the affection was located in the diagonal branch of the left coronary artery. Stenosis of the left coronary artery trunk was diagnosed in one case. The correlation analysis revealed a strongly significant positive correlation between content of anti-OLDL and the degree of CS.
  
  
  CONCLUSIONS
  The level of anti-OLDL in CHD patients directly correlates with the degree of CS and is a marker of coronary atherosclerosis severity.
authors.forename: S A
authors.initials: SA
authors.lastname: Urazgil'deeva
authors.forename: A Iu
authors.initials: AIu
authors.lastname: Titkov
authors.forename: L V
authors.initials: LV
authors.lastname: Vasina
authors.forename: V V
authors.initials: VV
authors.lastname: Tsaregorodtseva
authors.forename: V S
authors.initials: VS
authors.lastname: Gurevich
mesh_terms: D000328:Adult; D000368:Aged; D001323:Autoantibodies / Q000097:blood*; D017023:Coronary Angiography; D023921:Coronary Stenosis / Q000097:blood* / Q000209:etiology / Q000276:immunology; D003627:Data Interpretation, Statistical; D005260:Female; D006801:Humans; D016014:Linear Models; D008055:Lipids / Q000097:blood; D008077:Lipoproteins, LDL / Q000097:blood / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000097:blood* / Q000150:complications / Q000276:immunology; D011237:Predictive Value of Tests; D012720:Severity of Illness Index
chemical_list: D001323:Autoantibodies; D008055:Lipids; D008077:Lipoproteins, LDL