title: [Application of chemiluminescence immunoassay method in detection of serum index for liver fibrosis in patients with advanced schistosomiasis].
abstract: The method of chemiluminescence immunoassay (CLIA) was adopted to detect the levels of hyaluronic acid (HA), laminin (LN), III procollagen (CP III), IV collagen (IV-C) in the sera of 102 cases of advanced schistosomiasis. The results showed that the levels of the 4 indexes of advanced schistosomiasis patients were significantly higher than those of healthy people. It is suggested that the application of CLIA to detect the related serum indexes in patients with advanced schistosomiasis is useful in the diagnosis of liver fibrosis.
authors.affiliation: Dongzhi County Station of Schistosomiasis Control, Anhui Province, Dongzhi 247230, China.
authors.forename: Jiang-Long
authors.initials: JL
authors.lastname: Luo
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D024061:Collagen Type III / Q000097:blood; D024141:Collagen Type IV / Q000097:blood; D005260:Female; D006801:Humans; D006820:Hyaluronic Acid / Q000097:blood; D007118:Immunoassay / Q000379:methods*; D007797:Laminin / Q000097:blood; D008103:Liver Cirrhosis / Q000097:blood / Q000175:diagnosis* / Q000469:parasitology; D049449:Luminescence; D008297:Male; D008875:Middle Aged; D012552:Schistosomiasis / Q000097:blood / Q000150:complications / Q000175:diagnosis*; D055815:Young Adult
chemical_list: D024061:Collagen Type III; D024141:Collagen Type IV; D007797:Laminin; D006820:Hyaluronic Acid