title: A morphometric study of the intestinal mucosa of rats submitted to omentoenteropexy.
abstract: BACKGROUND
  The omentoenteropexy technique was developed as an alternative method for intestinal neovascularization, due to the angiogenic properties of factors from the omentum.
  
  
  OBJECTIVE
  This study investigated changes in intestinal villi heights and crypts depths due to surgical techniques: seromiotomy with and without omentoenteropexy.
  
  
  METHODS
  Thirty rats were operated on, after being divided into three groups, namely GI, GII and GIII with 10 rats each. In the GI rats were submitted to omentoenteropexy; rats in GII were submitted only to a seromiotomy, and in the GIII only laparotomy. Sixty days after the first surgery, the animals were sacrificed and a segment of intestine was removed for histology using Masson's trichrome technique and morphometric study of intestinal mucosa.
  
  
  RESULTS
  The histological findings showed that seromiotomy with or without omentoenteropexy increased the length of intestinal villi when compared with GIII (only laparotomy) (analysis of variance: P = 0.0068; GI 38.88 ± 4.17; GII 39.41± 6.33; GIII 31.85 ± 5.56; GI = GII P>0.05; GII>GIII P<0.05; GI>GIII P<0.001).
  
  
  CONCLUSIONS
  No differences were demonstrated in relation to crypt depths between the groups (P = 0.60). Ongoing studies are being set forth by our group to add more data on the role of omentopexy as a tool to promote neovascularization and intestinal mucosal growth.
authors.affiliation: Departamento de Cirurgia, Patologia e Gastroenterologia Pediátrica, Faculdade de Medicina do ABC, Santo André, SP, Brasil. munozfernandes@gmail.com
authors.forename: Pedro Muñoz
authors.initials: PM
authors.lastname: Fernandez
authors.forename: Fabíola
authors.initials: F
authors.lastname: Pollachi
authors.forename: Rafael Alves
authors.initials: RA
authors.lastname: Cordeiro
authors.forename: Ana Maria A A
authors.initials: AM
authors.lastname: Mader
authors.forename: Wilson Roberto
authors.initials: WR
authors.lastname: Catapani
mesh_terms: D000818:Animals; D007413:Intestinal Mucosa / Q000098:blood supply* / Q000473:pathology; D008297:Male; D018919:Neovascularization, Physiologic; D009852:Omentum / Q000098:blood supply / Q000601:surgery*; D051381:Rats; D017208:Rats, Wistar