title: In vivo anti-inflammatory and in vitro antioxidant activities of Moroccan medicinal plants.
abstract: Five ethanol extracts of wild plants from the Casablanca region (Morocco) used in local traditional medicine for the treatment of inflammatory diseases were evaluated for their in vivo topical anti-inflammatory activity (inhibition of carrageenan-induced ear edema in mice) and in vitro antioxidant and antiradical properties (inhibition of linoleic acid oxidation, DPPH radical scavenging). All the extracts showed an anti-inflammatory effect: 300 microg/cm2 provoked edema reductions ranging from 22 to 28%. All the extracts also exerted radical scavenging and/or antioxidant properties, the most active plant being Mentha pulegium L. (Lamiaceae), which contained the highest amount of phenolics (339 mg/g), and flavonoids (16.7 mg/g).
authors.affiliation: Department of Chemistry, Hassan II University, Casablanca, Morocco 20 100. noune_moussaid@yahoo.fr
authors.forename: Mina
authors.initials: M
authors.lastname: Moussaid
authors.forename: Abd Elaziz
authors.initials: AE
authors.lastname: Elamrani
authors.forename: Nourdinne
authors.initials: N
authors.lastname: Bourhim
authors.forename: Mohamed
authors.initials: M
authors.lastname: Benaissa
mesh_terms: D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000737:chemistry / Q000494:pharmacology*; D000975:Antioxidants / Q000737:chemistry*; D007249:Inflammation / Q000188:drug therapy*; D008519:Medicine, Traditional; D051379:Mice; D009018:Morocco; D010946:Plants, Medicinal / Q000737:chemistry*
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D000975:Antioxidants