title: [Biochemical and genetic aspects of pathogenesis of schizophrenia].
abstract: Some molecular-biological and genetic concepts of development of schizophrenia are discussed. The main attention is paid to the ontogenetic aspect of dopaminergic disturbances and to role of risk factors, including stress, responsible for interaction between the nervous, endocrine, and immune systems during development of schizophrenia.
authors.forename: D K
authors.initials: DK
authors.lastname: Kambarova
authors.forename: A G
authors.initials: AG
authors.lastname: Golubev
mesh_terms: D000818:Animals; D001921:Brain / Q000254:growth & development / Q000378:metabolism; D019208:Brain-Derived Neurotrophic Factor / Q000378:metabolism; D004298:Dopamine / Q000235:genetics / Q000378:metabolism*; D018698:Glutamic Acid / Q000235:genetics / Q000378:metabolism*; D006801:Humans; D051379:Mice; D009419:Nerve Tissue Proteins / Q000235:genetics / Q000378:metabolism; D017448:Receptors, Dopamine D2 / Q000235:genetics / Q000378:metabolism*; D016194:Receptors, N-Methyl-D-Aspartate / Q000235:genetics / Q000378:metabolism; D012559:Schizophrenia / Q000235:genetics* / Q000378:metabolism*
chemical_list: D019208:Brain-Derived Neurotrophic Factor; C412476:DISC1 protein, human; D009419:Nerve Tissue Proteins; D017448:Receptors, Dopamine D2; D016194:Receptors, N-Methyl-D-Aspartate; D018698:Glutamic Acid; D004298:Dopamine