title: Enantioselective aquatic toxicity of current chiral pesticides.
abstract: Chiral pesticides are ubiquitous in the aquatic environment, and their enantioselectivities in aquatic toxicity are known to be complicated. The difference in enantioselective effects between enantiomers may sometimes differ by approximately 100-fold or more, which makes it important to incorporate enantioselective effects into the risk assessment of chiral pesticides. In this paper, we reviewed relevant work on the aquatic toxicity of chiral pesticides with an emphasis on the enantioselective aquatic toxicity under both chronic and acute exposure conditions. We provided a personal account of the importance of studies on molecular mechanisms of developmental toxicity and specific endpoints such as vitellogenin, yolk sac edema and pericardial edema in future research. Given the widespread use of chiral pesticides, we suggest that a more comprehensive understanding of the significance of enantioselective aquatic toxicity will be very helpful in improving risk assessment and regulation of chiral pesticides.
authors.affiliation: Research Centre of Environmental Science, Zhejiang University of Technology, Hangzhou 310032, People's Republic of China.
authors.forename: Quan
authors.initials: Q
authors.lastname: Zhang
authors.forename: Cui
authors.initials: C
authors.lastname: Wang
authors.forename: Xiaofeng
authors.initials: X
authors.lastname: Zhang
authors.forename: Daqing
authors.initials: D
authors.lastname: Jin
authors.forename: Changjiang
authors.initials: C
authors.lastname: Huang
authors.forename: Meirong
authors.initials: M
authors.lastname: Zhao
mesh_terms: D000818:Animals; D015415:Biomarkers / Q000378:metabolism; D000460:Chlorophyta / Q000187:drug effects; D003621:Daphnia; D052244:Endocrine Disruptors / Q000737:chemistry / Q000633:toxicity; D010575:Pesticides / Q000737:chemistry / Q000633:toxicity*; D013237:Stereoisomerism; D014874:Water Pollutants, Chemical / Q000737:chemistry / Q000633:toxicity*
chemical_list: D015415:Biomarkers; D052244:Endocrine Disruptors; D010575:Pesticides; D014874:Water Pollutants, Chemical