title: [Intracerebral haemorrhage and postpartum cerebral angiopathy associated with the administration of sulprostone and norepinephrine].
abstract: We report the case of a 29-year-old female who had developed a postpartum cerebral angiopathy (PCA) complicated by an intracerebral haematoma and convulsions, after a postpartum haemorrhage with sulprostone and norepinephrine infusion. PCA is an under diagnosed neurovascular pathology, responsible of reversible and non-specific symptoms. However, it can be complicated by haemorrhagic or ischemic stroke with vital or functional risks. As PCA is favored by vasoactive treatments, their administration in peripartum period, when it is imperative, should be strictly controlled.
authors.affiliation: Service de réanimation polyvalente, centre hospitalier régional, Saint-Pierre, France. yann.ruzic@gmail.com
authors.forename: Y
authors.initials: Y
authors.lastname: Ruzic
authors.forename: D
authors.initials: D
authors.lastname: Tran-Van
authors.forename: A
authors.initials: A
authors.lastname: Omarjee
authors.forename: M
authors.initials: M
authors.lastname: Boukerrou
authors.forename: A
authors.initials: A
authors.lastname: Winer
mesh_terms: D000328:Adult; D001921:Brain / Q000000981:diagnostic imaging; D002533:Cerebral Angiography; D002561:Cerebrovascular Disorders / Q000139:chemically induced*; D015232:Dinoprostone / Q000009:adverse effects / Q000031:analogs & derivatives*; D005260:Female; D006801:Humans; D020300:Intracranial Hemorrhages / Q000139:chemically induced*; D007427:Intracranial Pressure / Q000502:physiology; D009638:Norepinephrine / Q000009:adverse effects*; D049590:Postpartum Period; D012121:Respiration, Artificial; D012151:Resuscitation; D012640:Seizures / Q000139:chemically induced; D014057:Tomography, X-Ray Computed; D014662:Vasoconstrictor Agents / Q000009:adverse effects*
chemical_list: D014662:Vasoconstrictor Agents; C016767:sulprostone; D015232:Dinoprostone; D009638:Norepinephrine