title: The prognostic nutritional index can be a prognostic indicator in colorectal carcinoma.
abstract: OBJECTIVE
  Preoperative assessments regarding a patient's immunological and nutritional condition are required to predict the outcomes of patients with malignant tumors. The aim of the current study was to clarify the significance of Onodera's prognostic nutritional index (OPNI), which can simply account for the immunological and nutritional conditions, in patients with colorectal carcinoma.
  
  
  METHODS
  The correlations of the preoperative OPNI value with clinicopathological features were examined in 219 patients with colorectal carcinoma who had been surgically treated.
  
  
  RESULTS
  Not only the tumor stage (P = 0.028) and venous invasion (P = 0.002), but also an OPNI of less than 40 (P = 0.002) were found to be independently correlated with a worse prognosis of patients with colorectal carcinoma.
  
  
  CONCLUSIONS
  The preoperative OPNI can be used as a simple prognostic indicator in colorectal carcinoma.
authors.affiliation: Department of Surgery, Fukuoka Higashi Medical Center, 1-1-1 Chidori, Koga, Japan. paper7777@yahoo.co.jp
authors.forename: Tadahiro
authors.initials: T
authors.lastname: Nozoe
authors.forename: Mayuko
authors.initials: M
authors.lastname: Kohno
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Iguchi
authors.forename: Emiko
authors.initials: E
authors.lastname: Mori
authors.forename: Takashi
authors.initials: T
authors.lastname: Maeda
authors.forename: Akito
authors.initials: A
authors.lastname: Matsukuma
authors.forename: Takahiro
authors.initials: T
authors.lastname: Ezaki
mesh_terms: D000230:Adenocarcinoma / Q000097:blood* / Q000401:mortality / Q000473:pathology* / Q000556:secondary / Q000601:surgery; D002288:Adenocarcinoma, Mucinous / Q000097:blood* / Q000401:mortality / Q000473:pathology* / Q000556:secondary / Q000601:surgery; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002278:Carcinoma in Situ / Q000097:blood / Q000401:mortality / Q000473:pathology / Q000601:surgery; D015179:Colorectal Neoplasms / Q000097:blood* / Q000401:mortality / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D018655:Lymphocyte Count; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D015596:Nutrition Assessment; D011379:Prognosis; D012709:Serum Albumin / Q000378:metabolism; D015996:Survival Rate; D055815:Young Adult
chemical_list: D012709:Serum Albumin