title: The neuropsychology of prefrontal function in antisocial personality disordered offenders with varying degrees of psychopathy.
abstract: BACKGROUND
  Despite methodological differences between studies, it has been suggested that psychopathy may be associated with a ventromedial prefrontal cortex (VMPFC) deficit and antisocial personality disorder (ASPD), as classified in the DSM-IV, with a broader range of deficits in dorsolateral prefrontal cortex (DLPFC) and VMPFC function.
  
  
  METHODS
  Ninety-six male offenders with ASPD who were assessed using the psychopathy checklist: screening version (PCL:SV) and 49 male right-handed healthy controls (HCs), matched for age and IQ, completed a neuropsychological test battery.
  
  
  RESULTS
  Offenders with ASPD displayed subtle impairments on executive function tasks of planning ability and set shifting and behavioural inhibition compared to HCs. However, among the offenders with ASPD there was no significant association between executive function impairment and scores on the measure of psychopathy.
  
  
  CONCLUSIONS
  Psychopathic traits in offenders with ASPD are not associated with greater executive function impairment.
authors.affiliation: Centre for Forensic Behavioural Science, Monash University, Clifton Hill, VIC, Australia. Mairead.dolan@forensicare.vic.gov.au
authors.forename: M
authors.initials: M
authors.lastname: Dolan
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D000987:Antisocial Personality Disorder / Q000503:physiopathology* / Q000523:psychology; D016022:Case-Control Studies; D057237:Criminals / Q000523:psychology*; D004739:England; D056344:Executive Function / Q000502:physiology*; D007839:Functional Laterality; D006801:Humans; D007266:Inhibition, Psychological; D008297:Male; D009483:Neuropsychological Tests / Q000706:statistics & numerical data; D009484:Neuropsychology; D017397:Prefrontal Cortex / Q000503:physiopathology*; D011329:Prisoners / Q000523:psychology; D011569:Psychiatric Status Rating Scales; D011930:Reaction Time