title: Pancreatic metastasis from renal cell carcinoma.
abstract: BACKGROUND
  Pancreatic metastases from renal cell carcinoma are uncommon.
  
  
  METHODS
  Retrospective study of 8 patients with a diagnosis of pancreatic metastasis from renal cell carcinoma observed in our Institute.
  
  
  RESULTS
  Patients were 6 (75%) males and 2 (25%) females. Mean age was 65.3 years. In 5 patients (57.1%), symptoms were present. The median interval of onset from nephrectomy was 10 years. No cases of synchronous pancreatic metastases were observed. Surgical resection was performed in 7 (87.5%) patients. At pathological examination, solitary metastases were identified in 5 patients (71.4%). No post-operative mortality was observed; the morbidity rate was 42.8%. In the group of patients who underwent pancreatic resection, median overall survival was 43.0 months (range 12.9-74.5), median disease-free survival was 23.6 months (range 9.9-74.5).
  
  
  CONCLUSIONS
  Pancreatic metastasis from renal cell carcinoma typically occurs after a long period from the initial nephrectomy, and seems to be related to a good prognosis.
authors.affiliation: Department of Surgery, Sant'Orsola-Malpighi Hospital, Bologna, Italy. marielda.dambra@hotmail.it
authors.forename: Marielda
authors.initials: M
authors.lastname: D'Ambra
authors.forename: Claudio
authors.initials: C
authors.lastname: Ricci
authors.forename: Riccardo
authors.initials: R
authors.lastname: Casadei
authors.forename: Francesco
authors.initials: F
authors.lastname: Minni
mesh_terms: D000368:Aged; D002292:Carcinoma, Renal Cell / Q000453:epidemiology / Q000556:secondary* / Q000601:surgery; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D007558:Italy / Q000453:epidemiology; D007680:Kidney Neoplasms / Q000453:epidemiology / Q000473:pathology* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D010190:Pancreatic Neoplasms / Q000453:epidemiology / Q000556:secondary* / Q000601:surgery*; D016577:Pancreaticoduodenectomy; D012189:Retrospective Studies; D015996:Survival Rate; D016896:Treatment Outcome