title: Allosteric modulation of seven transmembrane spanning receptors: theory, practice, and opportunities for central nervous system drug discovery.
authors.affiliation: Department of Pharmacology, Vanderbilt University Medical Center, Nashville, Tennessee 37232, United States.
authors.forename: Bruce J
authors.initials: BJ
authors.lastname: Melancon
authors.forename: Corey R
authors.initials: CR
authors.lastname: Hopkins
authors.forename: Michael R
authors.initials: MR
authors.lastname: Wood
authors.forename: Kyle A
authors.initials: KA
authors.lastname: Emmitte
authors.forename: Colleen M
authors.initials: CM
authors.lastname: Niswender
authors.forename: Arthur
authors.initials: A
authors.lastname: Christopoulos
authors.forename: P Jeffrey
authors.initials: PJ
authors.lastname: Conn
authors.forename: Craig W
authors.initials: CW
authors.lastname: Lindsley
mesh_terms: D000494:Allosteric Regulation; D000818:Animals; D002491:Central Nervous System Agents / Q000737:chemistry* / Q000494:pharmacology*; D055808:Drug Discovery; D006801:Humans; D008024:Ligands; D043562:Receptors, G-Protein-Coupled / Q000819:agonists / Q000037:antagonists & inhibitors / Q000378:metabolism*; D018094:Receptors, Metabotropic Glutamate / Q000378:metabolism; D011976:Receptors, Muscarinic / Q000378:metabolism; D013329:Structure-Activity Relationship
chemical_list: D002491:Central Nervous System Agents; D008024:Ligands; D043562:Receptors, G-Protein-Coupled; D018094:Receptors, Metabotropic Glutamate; D011976:Receptors, Muscarinic