title: Polycystic kidney disease in 2011: Connecting the dots toward a polycystic kidney disease therapy.
abstract: Understanding the complex interactions between the various pathways disrupted in polycystic kidney and liver disease is essential to identify and optimize therapies for these disorders. Studies published in the past year have demonstrated a functional interaction between the main proteins implicated in these diseases and identified novel therapeutic approaches.
authors.affiliation: Division of Nephrology and Hypertension, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA. torres.vicente@mayo.edu
authors.forename: Vicente E
authors.initials: VE
authors.lastname: Torres
authors.forename: Peter C
authors.initials: PC
authors.lastname: Harris
mesh_terms: D000818:Animals; D020022:Genetic Predisposition to Disease; D015316:Genetic Therapy / Q000379:methods*; D006801:Humans; D007690:Polycystic Kidney Diseases / Q000235:genetics / Q000628:therapy*; D050396:TRPP Cation Channels / Q000235:genetics / Q000378:metabolism*; D016896:Treatment Outcome
chemical_list: D050396:TRPP Cation Channels