title: [Two-nuclear neurons: sincitial fusion or amitotic division].
abstract: In the review the history of research two-nuclear neurons is stated and two hypotheses about mechanisms of their formation are analysed: by sincitial fusion or amytotic divisions. The facts of discrepancy of the former orthodox cellular theory categorically denying possibility sincitial of communications in nervous system and of sincitial fusion neurons are mentioned. As an example results of ultrastructural researches of occurrence sincitium in a cortex of the big brain of rats, in autonomic ganglions, in hypocampus and a cerebellum of adult animals are presented. The video data of the sincitial fusion of live neurons and the mechanism of formation multinuclear neurons in tissue culture are analyzed. Existing data about amytotic a way of formation two-nuclear neurons are critically considered. The conclusion becomes, that the mechanism of formation two-nuclear neurons is cellular fusion. Simultaneously the review confirms our representations about existence in nervous system sincitial interneural communications.
authors.forename: O S
authors.initials: OS
authors.lastname: Sotnikov
authors.forename: L E
authors.initials: LE
authors.lastname: Frumkina
authors.forename: A A
authors.initials: AA
authors.lastname: Lactionova
authors.forename: N M
authors.initials: NM
authors.lastname: Paramonova
authors.forename: S A
authors.initials: SA
authors.lastname: Novakovskaia
mesh_terms: D000818:Animals; D002450:Cell Communication / Q000502:physiology*; D018929:Cell Culture Techniques; D002459:Cell Fusion; D002467:Cell Nucleus / Q000648:ultrastructure*; D002478:Cells, Cultured; D005724:Ganglia / Q000166:cytology*; D006168:Guinea Pigs; D008854:Microscopy, Electron; D009474:Neurons / Q000502:physiology / Q000648:ultrastructure; D053141:Organelle Size / Q000502:physiology; D011817:Rabbits