title: Bacterial adhesion-resistant poly(2-hydroxyethyl methacrylate) derivative for mammalian cell cultures.
abstract: In an attempting to find new biomaterials for mammalian cell culture, PHEMA derivatives with ester side groups are synthesized by one-step polymer-analogous reaction. These polymers show excellent antifouling properties against S. epidermidis and P. aeruginosa while their cytotoxicity and proliferation activity for HDF cell are on a similar level as commercially available TCPS. The interesting bioadhesion property is systematically correlated with surface properties of the PHEMA derivatives.
authors.affiliation: Department of Chemical and Biological Engineering, Seoul National University, Seoul, Republic of Korea.
authors.forename: Eun-Ho
authors.initials: EH
authors.lastname: Sohn
authors.forename: Jooyeon
authors.initials: J
authors.lastname: Ahn
authors.forename: Suk Ho
authors.initials: SH
authors.lastname: Bhang
authors.forename: Junil
authors.initials: J
authors.lastname: Kang
authors.forename: Jeyong
authors.initials: J
authors.lastname: Yoon
authors.forename: Byung-Soo
authors.initials: BS
authors.lastname: Kim
authors.forename: Jong-Chan
authors.initials: JC
authors.lastname: Lee
mesh_terms: D001422:Bacterial Adhesion / Q000187:drug effects; D001672:Biocompatible Materials / Q000138:chemical synthesis / Q000494:pharmacology*; D018929:Cell Culture Techniques; D002470:Cell Survival / Q000187:drug effects; D002478:Cells, Cultured; D020405:Dermis / Q000166:cytology / Q000187:drug effects*; D005347:Fibroblasts / Q000166:cytology / Q000187:drug effects*; D006244:Hardness; D006801:Humans; D050296:Microbial Viability / Q000187:drug effects*; D011102:Polyhydroxyethyl Methacrylate / Q000138:chemical synthesis / Q000494:pharmacology*; D011550:Pseudomonas aeruginosa / Q000187:drug effects; D013212:Staphylococcus epidermidis / Q000187:drug effects; D013499:Surface Properties
chemical_list: D001672:Biocompatible Materials; D011102:Polyhydroxyethyl Methacrylate