title: Psychophysical correlates in adults with sensory modulation disorder.
abstract: OBJECTIVE
  Individuals with sensory modulation disorder (SMD) demonstrate abnormal responses to naturally occurring stimuli in a manner that interferes with daily life activities. This study is the first study applying quantitative sensory testing to characterize the somatosensory sensitivity of adults with SMD.
  
  
  METHODS
  One hundred and fifty one adults (68 males and 83 females) were tested comparing 91 SMD to 60 SMD-free, control individuals. Group placement (SMD vs. SMD-free) was determined using the Sensory Responsiveness Questionnaire (SRQ). Sensory detection thresholds for skin warming, cooling, punctate dynamic tactile sensation, vibration and thermal pain thresholds for heat and cold stimuli were determined at several body sites. Pinprick pain and prickliness were also assessed, as well as the duration and intensity of the after-sensations of prickliness and pain evoked by the prickly stimuli.
  
  
  RESULTS
  Compared to control adults, individuals with SMD showed significantly higher pain intensity to prickle stimuli, marginally higher pain intensity to pinprick and hypoesthesia to punctate dynamic tactile sensation at one of two sites tested.
  
  
  CONCLUSIONS
  These results are in line with our previous study that investigated children with SMD using the same stimuli, and found similar results. We suggest a CNS involvement as the underlying mechanisms in SMD.
authors.affiliation: School of Occupational Therapy, Faculty of Medicine of Hadassah and the Hebrew University of Jerusalem, Jerusalem, Israel.
authors.forename: Tami
authors.initials: T
authors.lastname: Bar-Shalita
authors.forename: Jean-Jacques
authors.initials: JJ
authors.lastname: Vatine
authors.forename: Shula
authors.initials: S
authors.lastname: Parush
authors.forename: Lisa
authors.initials: L
authors.lastname: Deutsch
authors.forename: Ze'ev
authors.initials: Z
authors.lastname: Seltzer
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010147:Pain Measurement; D058748:Pain Perception / Q000502:physiology; D010812:Physical Stimulation / Q000379:methods; D011601:Psychophysics; D011930:Reaction Time / Q000502:physiology; D012677:Sensation / Q000502:physiology*; D012678:Sensation Disorders / Q000503:physiopathology* / Q000523:psychology*; D012684:Sensory Thresholds / Q000502:physiology*; D011795:Surveys and Questionnaires