title: Wells' syndrome associated with parvovirus in a 5-year old boy.
abstract: Wells' syndrome, otherwise known as eosinophilic cellulitis, is a rare dermatosis seen more commonly in adults than in children. In this article, we present a 5-year-old Caucasian boy who initially presented with pruritic, erythematous macules and papules evolving to bullae formation. Subsequent histology confirmed diagnosis of Wells' syndrome, and additional blood work also demonstrated positive immunoglobulin (Ig)M and IgG for parvovirus. In many instances, the direct etiology of Wells' syndrome is unclear, but the link between parvoviral infection and development of Wells' syndrome could further support an additional cause.
authors.affiliation: Austin Diagnostic Clinic Private Practice, Austin, Texas, USA.
authors.forename: Eric
authors.initials: E
authors.lastname: Cherng
authors.forename: Amy A
authors.initials: AA
authors.lastname: McClung
authors.forename: Harry M
authors.initials: HM
authors.lastname: Rosenthal
authors.forename: John
authors.initials: J
authors.lastname: Hicks
authors.forename: Moise L
authors.initials: ML
authors.lastname: Levy
mesh_terms: D000914:Antibodies, Viral / Q000097:blood; D001706:Biopsy; D002481:Cellulitis / Q000473:pathology* / Q000821:virology*; D002675:Child, Preschool; D004802:Eosinophilia / Q000473:pathology* / Q000821:virology*; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D008297:Male; D010322:Parvoviridae Infections / Q000276:immunology / Q000473:pathology*; D016732:Parvovirus B19, Human / Q000276:immunology / Q000302:isolation & purification*
chemical_list: D000914:Antibodies, Viral; D007074:Immunoglobulin G; D007075:Immunoglobulin M