title: Aptamer optical biosensor without bio-breakage using upconversion nanoparticles as donors.
abstract: LRET-based optical biosensor of an aptamer-upconversion conjugate was constructed. It is demonstrated that photosensitized breakage and damage of aptamers are eliminated by employing UCNPs as donors, and the as-designed biosensor is specific and sensitive in the detection of ATP.
authors.affiliation: Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Sciences, P. R. China.
authors.forename: Kai
authors.initials: K
authors.lastname: Song
authors.forename: Xianggui
authors.initials: X
authors.lastname: Kong
authors.forename: Xiaomin
authors.initials: X
authors.lastname: Liu
authors.forename: Youlin
authors.initials: Y
authors.lastname: Zhang
authors.forename: Qinghui
authors.initials: Q
authors.lastname: Zeng
authors.forename: Langping
authors.initials: L
authors.lastname: Tu
authors.forename: Zhan
authors.initials: Z
authors.lastname: Shi
authors.forename: Hong
authors.initials: H
authors.lastname: Zhang
mesh_terms: D052157:Aptamers, Nucleotide / Q000737:chemistry* / Q000235:genetics; D001483:Base Sequence; D015374:Biosensing Techniques / Q000379:methods*; D008163:Luminescent Measurements; D053758:Nanoparticles / Q000737:chemistry*; D055620:Optical Phenomena
chemical_list: D052157:Aptamers, Nucleotide