title: Directing group-controlled hydrosilylation: regioselective functionalization of alkyne.
abstract: Pt(0)-catalyzed hydrosilylation of unsymmetric alkynes proceeds in a highly regioselective manner with a dimethylvinylsilyl (DMVS) group as the directing group. This hydrosilylation affords a single regioisomer of silylalkenes from propargylic and homopropargylic alcohol derivatives. DMVS also has an accelerating effect that allows group-selective hydrosilylation of the DMVS-attached alkyne prior to that of other alkynes. Combined hydrosilylation and transformation reactions of the resulting silylalkenes afford various tri-substituted alkenes and multi-oxy-functionalized compounds with high regioselectivity from unsymmetric alkynes.
authors.affiliation: Department of Molecular and Material Sciences, Kyushu University, Kasuga, Fukuoka 816-8580, Japan.
authors.forename: Yuuya
authors.initials: Y
authors.lastname: Kawasaki
authors.forename: Youhei
authors.initials: Y
authors.lastname: Ishikawa
authors.forename: Kazunobu
authors.initials: K
authors.lastname: Igawa
authors.forename: Katsuhiko
authors.initials: K
authors.lastname: Tomooka