title: Enrichment and detection of peptides from biological systems using designed periodic mesoporous organosilica microspheres.
abstract: Periodic mesoporous organosilica microspheres (PMOMs) are designed with integrated structural features, including a cubic mesostructure, hydrophobic wall composition, a uniform pore size of ≈3 nm, and a spherical morphology in micrometers, all advantageous for size-selective and highly efficient enrichment of peptides from mixtures. Consequently, PMOMs can be used to capture peptides in a range of complex biological systems.
authors.affiliation: Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Brisbane, QLD 4072, Australia Fax: (+)61-7-33463973.
authors.forename: Kun
authors.initials: K
authors.lastname: Qian
authors.forename: Wenyi
authors.initials: W
authors.lastname: Gu
authors.forename: Pei
authors.initials: P
authors.lastname: Yuan
authors.forename: Fang
authors.initials: F
authors.lastname: Liu
authors.forename: Yunhua
authors.initials: Y
authors.lastname: Wang
authors.forename: Michael
authors.initials: M
authors.lastname: Monteiro
authors.forename: Chengzhong
authors.initials: C
authors.lastname: Yu
mesh_terms: D000818:Animals; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D051379:Mice; D008854:Microscopy, Electron; D008863:Microspheres; D058608:Nanopores / Q000648:ultrastructure; D017646:Organosilicon Compounds / Q000737:chemistry; D050725:Papillomavirus E7 Proteins / Q000302:isolation & purification; D010316:Particle Size; D010455:Peptides / Q000302:isolation & purification*; D016062:Porosity; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; D017550:Spectroscopy, Fourier Transform Infrared; D014961:X-Ray Diffraction
chemical_list: D017646:Organosilicon Compounds; D050725:Papillomavirus E7 Proteins; D010455:Peptides