title: Corneal haze following disruption of epithelial basement membrane on ultra-high-resolution OCT following femtosecond LASIK.
abstract: OBJECTIVE
  To analyze in vivo structural properties of a case with interface haze that developed after femtosecond laser-assisted LASIK.
  
  
  METHODS
  Case report.
  
  
  RESULTS
  A 42-year-old man underwent uncomplicated LASIK. Four months after the surgery he developed regression of his refractive error and interface haze in both eyes. Flap thickness was calculated as 73 μm and 81 μm in the right and left eyes, respectively. A novel ultra-high-resolution spectral domain optical coherence tomography (OCT) system was used to demonstrate in vivo morphology of the cornea. On ultra-high-resolution OCT, haze was demonstrated as increased bright white reflectivity of the flap interface. Areas of focal disruption of the basement membrane and Bowman layer corresponded with the most significant areas of interface haze.
  
  
  CONCLUSIONS
  Our results support the hypothesis that haze after femtosecond LASIK may be a result of damage to the basement membrane and Bowman layer of the cornea.
authors.affiliation: Bascom Palmer Eye Institute, University of Miami, Miller School of Medicine, Miami, FL 33136, USA.
authors.forename: Pravin K
authors.initials: PK
authors.lastname: Vaddavalli
authors.forename: Volkan
authors.initials: V
authors.lastname: Hurmeric
authors.forename: Jianhua
authors.initials: J
authors.lastname: Wang
authors.forename: Sonia H
authors.initials: SH
authors.lastname: Yoo
mesh_terms: D000328:Adult; D001485:Basement Membrane / Q000473:pathology*; D050541:Bowman Membrane / Q000473:pathology*; D003318:Corneal Opacity / Q000175:diagnosis / Q000209:etiology*; D003319:Corneal Stroma / Q000601:surgery*; D006801:Humans; D020731:Keratomileusis, Laser In Situ / Q000009:adverse effects*; D054018:Lasers, Excimer / Q000009:adverse effects*; D008297:Male; D009216:Myopia / Q000601:surgery*; D013524:Surgical Flaps / Q000473:pathology; D041623:Tomography, Optical Coherence