title: A portable device for experimental treatment of neurogenic detrusor overactivity.
abstract: The objective of this study was to evaluate the effect of automatic event-driven electrical stimulation on the dorsal penile/clitoral nerve for management of neurogenic detrusor overactivity in spinal cord injured subjects. In order to reach the objectives it was necessary to design and realize a portable device for ambulatory urodynamic studies which was able to activate an electrical stimulator when the detrusor pressure exceeded a certain threshold. The developed device was repeatedly tested in a healthy subject and subsequently tested in a spinal cord injured subject. In testing the automatic event-driven system in the spinal cord injured subject, detrusor contractions were successfully inhibited until a certain bladder volume was reached and no incontinence episodes were observed prior to disabling the system. The preliminary results indicate that automatic event-driven electrical stimulation on the dorsal penile/clitoral nerve can inhibit involuntary detrusor contractions in spinal cord injured subjects and hereby restore continence and increase bladder capacity.
authors.affiliation: Center for Sensory-Motor Interaction (SMI), Department of Health Science and Technology, Aalborg University, Denmark.
authors.forename: M V
authors.initials: MV
authors.lastname: Fjorback
authors.forename: J
authors.initials: J
authors.lastname: Hansen
authors.forename: A L
authors.initials: AL
authors.lastname: Dalmose
authors.forename: N J M
authors.initials: NJ
authors.lastname: Rijkhoff
authors.forename: T
authors.initials: T
authors.lastname: Sinkjaer