title: Anaemia during pregnancy: impact on birth outcome and infant haemoglobin level during the first 18 months of life.
abstract: To determine the effect of maternal anaemia on pregnancy outcome and describe its impact on infant haemoglobin level in the first 18 months of life, we conducted a prospective study of 617 pregnant women and their children in Benin. Prevalence of maternal anaemia at delivery was 39.5%, and 61.1% of newborns were anaemic at birth. Maternal anaemia was not associated with low birth weight [OR = 1.2 (0.6-2.2)] or preterm birth [OR = 1.3 (0.7-2.4)], whereas the newborn's anaemia was related to maternal anaemia [OR = 1.8 (1.2-2.5)]. There was no association between an infant's haemoglobin level until 18 months and maternal anaemia. However, malaria attacks during follow-up, male gender and sickle cell trait were all associated with a lower infant haemoglobin level until 18 months, whereas good infant feeding practices and a polygamous family were positively associated with a higher haemoglobin level during the first 18 months of life.
authors.affiliation: IRD UMR216, Mère et enfant face aux infections tropicales, Paris, France. kourakobtoghislain@yahoo.fr
authors.forename: Ghislain K
authors.initials: GK
authors.lastname: Koura
authors.forename: Smaïla
authors.initials: S
authors.lastname: Ouedraogo
authors.forename: Agnès
authors.initials: A
authors.lastname: Le Port
authors.forename: Laurence
authors.initials: L
authors.lastname: Watier
authors.forename: Gilles
authors.initials: G
authors.lastname: Cottrell
authors.forename: José
authors.initials: J
authors.lastname: Guerra
authors.forename: Isabelle
authors.initials: I
authors.lastname: Choudat
authors.forename: Antoine
authors.initials: A
authors.lastname: Rachas
authors.forename: Julie
authors.initials: J
authors.lastname: Bouscaillou
authors.forename: Achille
authors.initials: A
authors.lastname: Massougbodji
authors.forename: André
authors.initials: A
authors.lastname: Garcia
mesh_terms: D000293:Adolescent; D000328:Adult; D000740:Anemia / Q000097:blood / Q000150:complications* / Q000453:epidemiology; D001541:Benin / Q000453:epidemiology; D005190:Family; D005247:Feeding Behavior; D005260:Female; D005500:Follow-Up Studies; D006454:Hemoglobins / Q000378:metabolism*; D006801:Humans; D007223:Infant; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000097:blood* / Q000453:epidemiology; D008288:Malaria / Q000097:blood* / Q000150:complications; D008393:Marriage; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000097:blood* / Q000453:epidemiology; D011256:Pregnancy Outcome; D047928:Premature Birth; D015995:Prevalence; D011446:Prospective Studies; D012737:Sex Factors; D012805:Sickle Cell Trait / Q000097:blood* / Q000150:complications; D055815:Young Adult
chemical_list: D006454:Hemoglobins