title: [Management of analgesics in cancer patients with renal impairment].
abstract: Pain is frequent in cancer patients. To date, there is a consequent therapeutic arsenal so to manage pain; the different treatment strategies are the subject of various recommendations. Patients with cancer also frequently suffer from renal insufficiency, and this comorbidity may disrupt or jeopardize the analgesic strategy by changing the risk-benefit ratio of treatment options. This article provides recommendations for the use of drugs used for pain treatment after pointing out: 1) etiological and pathophysiological elements of pain; 2) therapeutic strategies for pain management; 3) data regarding renal failure in cancer and; 4) a point on drugs pharmacokinetics.
authors.affiliation: Institut Jean-Godinot, CLCC de Reims, département de pharmacie, France. jean-baptiste.rey@reims.unicancer.fr
authors.forename: Jean-Baptiste
authors.initials: JB
authors.lastname: Rey
authors.forename: Thao
authors.initials: T
authors.lastname: Tran
authors.forename: Didier
authors.initials: D
authors.lastname: Ammar
authors.forename: Damien
authors.initials: D
authors.lastname: Parent
authors.forename: Nicolas
authors.initials: N
authors.lastname: Janus
authors.forename: Vincent
authors.initials: V
authors.lastname: Launay-Vacher
mesh_terms: D000700:Analgesics / Q000008:administration & dosage*; D006801:Humans; D008487:Medical History Taking / Q000379:methods; D009369:Neoplasms / Q000150:complications*; D010146:Pain / Q000188:drug therapy* / Q000209:etiology / Q000503:physiopathology; D059408:Pain Management / Q000379:methods*; D051437:Renal Insufficiency / Q000150:complications*; D011795:Surveys and Questionnaires
chemical_list: D000700:Analgesics