title: Correlation of fundus autofluorescence gray values with vision and microperimetry in resolved central serous chorioretinopathy.
abstract: OBJECTIVE
  To evaluate the prognostic value of grayscale parameters in fundus autofluorescence (FAF) for visual function in resolved central serous chorioretinopathy (CSC).
  
  
  METHODS
  Seventy-six eyes of 67 patients with CSC that had been resolved for more than 4 months were analyzed retrospectively. Both the short-wavelength (SW)-FAF and near infrared (NIR)-FAF gray value parameters, including the mean, standard deviation, and coefficient of variation (CV), were calculated at 350-μm- and 1200-μm-diameter circles centered on the fovea. The FAF gray value parameters correlated with -logMAR best corrected visual acuity (BCVA) and mean microperimetry (MP) at the 2° and 4° diameters from the foveal center.
  
  
  RESULTS
  The mean -logMAR BCVA was 0.15 ± 0.23. The mean MP was 12.87 ± 3.79 dB at 2° and 13.54 ± 3.37 dB at 4°. The -logMAR BCVA correlated most strongly with the mean SW-FAF gray value at the 350-μm circle centered around the fovea (SW-M350; ρ = 0.353; P = 0.002), and the SD of the SW-FAF gray value at the 350-μm circle centered around the fovea (SW-SD350) correlated most strongly with the MP at 2° (ρ = -0.416, P < 0.0001) and 4° (ρ = -0.435, P < 0.0001). The NIR-FAF gray value parameters did not correlate with the macular function tests.
  
  
  CONCLUSIONS
  In subjects with resolved CSC, FAF gray values correlated with visual function. BCVA correlated most strongly with SW-M350. MP at 2° and at 4° correlated most strongly with SW-SD350.
authors.affiliation: Department of Ophthalmology, Korea University College of Medicine, Seoul, Korea.
authors.forename: Jaeryung
authors.initials: J
authors.lastname: Oh
authors.forename: Seong-Woo
authors.initials: SW
authors.lastname: Kim
authors.forename: Soon-Sun
authors.initials: SS
authors.lastname: Kwon
authors.forename: In Kyung
authors.initials: IK
authors.lastname: Oh
authors.forename: Kuhl
authors.initials: K
authors.lastname: Huh
mesh_terms: D000328:Adult; D000368:Aged; D056833:Central Serous Chorioretinopathy / Q000175:diagnosis* / Q000503:physiopathology; D005260:Female; D005451:Fluorescein Angiography / Q000379:methods*; D005500:Follow-Up Studies; D005584:Fovea Centralis / Q000473:pathology* / Q000503:physiopathology; D005654:Fundus Oculi; D006801:Humans; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D011379:Prognosis; D020127:Recovery of Function; D015203:Reproducibility of Results; D012189:Retrospective Studies; D014792:Visual Acuity / Q000502:physiology*; D058609:Visual Field Tests / Q000379:methods*; D014794:Visual Fields / Q000502:physiology*