title: Colon distension and scan protocol for CT-colonography: an overview.
abstract: This article reviews two important aspects of CT-colonography, namely colonic distension and scan parameters. Adequate distension should be obtained to visualize the complete colonic lumen and optimal scan parameters should be used to prevent unnecessary radiation burden. For optimal distension, automatic carbon dioxide insufflation should be performed, preferably via a thin, flexible catheter. Hyoscine butylbromide is - when available - the preferred spasmolytic agent because of the positive effect on insufflation and pain/burden and its low costs. Scans in two positions are required for adequate distension and high polyp sensitivity and decubitus position may be used as an alternative for patients unable to lie in prone position. The great intrinsic contrast between air or tagging and polyps allows the use of low radiation dose. Low-dose protocol without intravenous contrast should be used when extracolonic findings are deemed unimportant. In patients suspected for colorectal cancer, normal abdominal CT scan protocols and intravenous contrast should be used in supine position for the evaluation of extracolonic findings. Dose reduction can be obtained by lowering the tube current and/or voltage. Tube current modulation reduces the radiation dose (except in obese patients), and should be used when available. Iterative reconstructions is a promising dose reducing tool and dual-energy CT is currently evaluated for its applications in CT-colonography. This review also provides our institution's insufflation procedure and scan parameters.
authors.affiliation: Department of Radiology, Academic Medical Center, University of Amsterdam, PB 22660, 1100 DD Amsterdam, The Netherlands. t.n.boellaard@amc.uva.nl
authors.forename: Thierry N
authors.initials: TN
authors.lastname: Boellaard
authors.forename: Margriet C
authors.initials: MC
authors.lastname: de Haan
authors.forename: Henk W
authors.initials: HW
authors.lastname: Venema
authors.forename: Jaap
authors.initials: J
authors.lastname: Stoker
mesh_terms: D002086:Butylscopolammonium Bromide / Q000008:administration & dosage; D002245:Carbon Dioxide; D003106:Colon / Q000000981:diagnostic imaging* / Q000187:drug effects; D023881:Colonography, Computed Tomographic / Q000379:methods*; D006801:Humans; D018727:Muscarinic Antagonists / Q000008:administration & dosage; D010276:Parasympatholytics / Q000008:administration & dosage; D011029:Pneumoradiography / Q000379:methods*; D011856:Radiographic Image Enhancement / Q000379:methods*
chemical_list: D018727:Muscarinic Antagonists; D010276:Parasympatholytics; D002245:Carbon Dioxide; D002086:Butylscopolammonium Bromide