title: Eosinophilic pneumonia: experience at two tertiary care referral hospitals in Saudi Arabia.
abstract: OBJECTIVE
  Eosinophilic lung diseases are a diverse group of disorders characterized by pulmonary opacities associated with tissue or peripheral eosinophilia.
  
  
  METHODS
  A retrospective study conducted at two tertiary care hospitals from January 1999 to December 2009.
  
  
  METHODS
  All cases with the diagnosis of pulmonary eosinophilia were reviewed over a period of 10 years. Data on demographic, clinical, and radiologic characteristics were collected.
  
  
  RESULTS
  Thirty-five patients with a mean age of 33.9 (16.2) years, of which 20 (57.1%) were male and meeting the criteria of eosinophilic lung disease were identified. Cough and dyspnea were the most frequent symptoms at presentation in 29 (82.9%) and 27 (77.1%) patients, respectively. Reticulonodular and airspace patterns were the most common radiographic findings in 17 (48.6%) and 15 (42.9%) patients, respectively. Peripheral eosinophilia was present in 33 (94.3%) patients. Twenty-four patients (68.6%) were labeled as having idiopathic pulmonary infiltrate with eosinophilia. Complete remission was achieved in 13 (54.2%) of 24 patients, while 10 (41.7%) patients relapsed within a few months of discontinuation of therapy. Specific therapy for a specific disease was administered in 8 patients: 2 patients for pulmonary tuberculosis, 2 for Churg-Strauss syndrome, 1 for lymphoma, 1 for schistosomiasis, 1 for acute eosinophilic pneumonia, and 1 for Wegener granuloma; 3 patients were treated as allergic bronchopulmonary aspergillosis.
  
  
  CONCLUSIONS
  Pulmonary eosinophilia remains rare but challenging, and it can have the same diverse clinical and radiographic presentations seen with other common pulmonary conditions. Clinicians should be alert to these syndromes and must think of them in any lung disease differential diagnoses.
authors.affiliation: Department of Medicine, Pulmonary Division, King Saud University for Health Sciences, King Abdulaziz Medical City, Riyadh, Saudi Arabia. Jahdali@ yahoo.com
authors.forename: Hamdan
authors.initials: H
authors.lastname: Al-Jahdali
authors.forename: Abdelkarim
authors.initials: A
authors.lastname: Waness
authors.forename: Suhaila
authors.initials: S
authors.lastname: Al-Jawder
authors.forename: Salim A
authors.initials: SA
authors.lastname: Baharoon
authors.forename: Saleh
authors.initials: S
authors.lastname: Al-Muhsen
authors.forename: Abdullah
authors.initials: A
authors.lastname: Al-Mobeireek
authors.forename: Reda
authors.initials: R
authors.lastname: Salama
authors.forename: Rabih
authors.initials: R
authors.lastname: Halwani
mesh_terms: D000293:Adolescent; D000328:Adult; D001229:Aspergillosis, Allergic Bronchopulmonary / Q000097:blood / Q000175:diagnosis / Q000000981:diagnostic imaging; D001999:Bronchoscopy; D015267:Churg-Strauss Syndrome / Q000097:blood / Q000175:diagnosis / Q000000981:diagnostic imaging; D003371:Cough / Q000097:blood / Q000175:diagnosis / Q000000981:diagnostic imaging; D003937:Diagnosis, Differential; D004417:Dyspnea / Q000097:blood / Q000175:diagnosis / Q000000981:diagnostic imaging; D005260:Female; D006761:Hospitals; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D011657:Pulmonary Eosinophilia / Q000097:blood / Q000175:diagnosis* / Q000000981:diagnostic imaging; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed; D014397:Tuberculosis, Pulmonary / Q000097:blood / Q000175:diagnosis / Q000000981:diagnostic imaging