title: Selective extraction and separation of oxymatrine from Sophora flavescens Ait. extract by silica-confined ionic liquid.
abstract: This study highlighted the application of a two-stepped extraction method for extraction and separation of oxymatrine from Sophora flavescens Ait. extract by utilizing silica-confined ionic liquids as sorbent. The optimized silica-confined ionic liquid was firstly mixed with plant extract to adsorb oxymatrine. Simultaneously, some interference, such as matrine, was removed. The obtained suspension was then added to a cartridge for solid phase extraction. Through these two steps, target compound was adequately separated from interferences with 93.4% recovery. In comparison with traditional solid phase extraction, this method accelerates loading and reduces the use of organic solvents during washing. Moreover, the optimization of loading volume was simplified as optimization of solid/liquid ratio.
authors.affiliation: Department of Chemical Engineering, Inha University, Nam-Ku, Incheon, Republic of Korea.
authors.forename: Wentao
authors.initials: W
authors.lastname: Bi
authors.forename: Minglei
authors.initials: M
authors.lastname: Tian
authors.forename: Kyung Ho
authors.initials: KH
authors.lastname: Row
mesh_terms: D000327:Adsorption; D000470:Alkaloids / Q000302:isolation & purification*; D002851:Chromatography, High Pressure Liquid; D007093:Imidazoles / Q000737:chemistry; D052578:Ionic Liquids / Q000737:chemistry*; D059625:Liquid-Liquid Extraction / Q000379:methods*; D000432:Methanol; D010936:Plant Extracts / Q000737:chemistry* / Q000302:isolation & purification; D011807:Quinolizines / Q000302:isolation & purification*; D012822:Silicon Dioxide / Q000737:chemistry; D029909:Sophora / Q000737:chemistry*; D013696:Temperature; D013997:Time Factors; D000093842:Matrines
chemical_list: D000470:Alkaloids; D007093:Imidazoles; D052578:Ionic Liquids; D000432:Methanol; D010936:Plant Extracts; D011807:Quinolizines; D012822:Silicon Dioxide; C037573:oxymatrine; D000093842:Matrines