title: Interpretation guidelines for multilocus STR forensic profiles from low template DNA samples.
abstract: Low template (LT) DNA testing is a more sensitive method of PCR DNA typing which tests lower quantities of DNA compared to traditional PCR DNA protocols. Methods applied in this testing involve amplification or postamplification efforts to increase detection sensitivity. Establishing the interpretation rules of the results obtained is condition sine qua non for successful incorporation of this valuable technique into forensic casework. Here we describe a successfully optimized and validated approach to interpretation of LT-DNA samples.
authors.affiliation: Department of Forensic Biology, New York City Office of Chief Medical Examiner, New York, NY, USA.
authors.forename: Zoran M
authors.initials: ZM
authors.lastname: Budimlija
authors.forename: Theresa A
authors.initials: TA
authors.lastname: Caragine
mesh_terms: D000483:Alleles; D004247:DNA / Q000235:genetics*; D053803:Forensic Genetics / Q000379:methods*; D017408:Guidelines as Topic; D006801:Humans; D018895:Microsatellite Repeats / Q000235:genetics*; D058885:Multilocus Sequence Typing / Q000379:methods*; D013698:Templates, Genetic
chemical_list: D004247:DNA