title: Cohesin and chromatin organisation.
abstract: Cohesin defines the topology of chromosomes in mitosis and meiosis by holding sister chromatids together; more recently a role for cohesin in chromatin organisation and gene expression in interphase has emerged.
authors.affiliation: Lymphocyte Development Group, MRC Clinical Sciences Centre, Imperial College London, London W12 0NN, UK. vlad.seitan@csc.mrc.ac.uk
authors.forename: Vlad C
authors.initials: VC
authors.lastname: Seitan
authors.forename: Matthias
authors.initials: M
authors.lastname: Merkenschlager
mesh_terms: D000818:Animals; D018797:Cell Cycle Proteins / Q000378:metabolism*; D002843:Chromatin / Q000737:chemistry / Q000378:metabolism; D002868:Chromosomal Proteins, Non-Histone / Q000378:metabolism*; D004261:DNA Replication; D015870:Gene Expression; D006801:Humans; D007399:Interphase; D014158:Transcription, Genetic; D000097722:Cohesins
chemical_list: D018797:Cell Cycle Proteins; D002843:Chromatin; D002868:Chromosomal Proteins, Non-Histone; D000097722:Cohesins