title: CarGene: characterisation of sets of genes based on metabolic pathways analysis.
abstract: The great amount of biological information provides scientists with an incomparable framework for testing the results of new algorithms. Several tools have been developed for analysing gene-enrichment and most of them are Gene Ontology-based tools. We developed a Kyoto Encyclopedia of Genes and Genomes (Kegg)-based tool that provides a friendly graphical environment for analysing gene-enrichment. The tool integrates two statistical corrections and simultaneously analysing the information about many groups of genes in both visual and textual manner. We tested the usefulness of our approach on a previous analysis (Huttenshower et al.). Furthermore, our tool is freely available (http://www.upo.es/eps/bigs/cargene.html).
authors.affiliation: School of Engineering, Pablo de Olavide University, 41013 Seville, Spain. aguilar@upo.es
authors.forename: Jesus S
authors.initials: JS
authors.lastname: Aguilar-Ruiz
authors.forename: Domingo S
authors.initials: DS
authors.lastname: Rodriguez-Baena
authors.forename: Norberto
authors.initials: N
authors.lastname: Diaz-Diaz
authors.forename: Isabel A
authors.initials: IA
authors.lastname: Nepomuceno-Chamorro
mesh_terms: D000818:Animals; D016208:Databases, Factual; D015870:Gene Expression; D005796:Genes; D016678:Genome; D053858:Metabolic Networks and Pathways / Q000235:genetics; D011506:Proteins / Q000235:genetics* / Q000378:metabolism; D012984:Software
chemical_list: D011506:Proteins