title: [A case of androgen insensitivity syndrome (AIS) treated by Laparoendoscopic single site surgery (LESS)].
abstract: A 20-year-old woman referred to our hospital for further examination of primary amenorrhea with high levels of testosterone (998 ng/ml). Inspite of having normal female external genitalia, she had 5 cm deep blind-ending vagina, absence of uterus and ovaries with the karyotype of 46,XY. Abdominal magnetic resonance imaging localized bilateral intra abdominal structures, which indicated bilateral testes. Thus, she was diagnosed with androgen insensitivity syndrome(AIS) based on both clinical and karyotypic evidence. She underwent laparoscopic bilateral gonadalectomy through a single incision at the navel and histological examination showed intratubular germ cell neoplasia (ITGCN). Her postoperative course was uneventful with less pain and a small surgical wound was only at the navel. Laparoendoscopic single site surgery (LESS) can be considered a surgical procedure for gonadalectomy in AIS patients.
authors.affiliation: The Department of Urology, Osaka University Graduate School of Medicine.
authors.forename: Nozomu
authors.initials: N
authors.lastname: Kishimoto
authors.forename: Masayoshi
authors.initials: M
authors.lastname: Okumi
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Miyagawa
authors.forename: Iwao
authors.initials: I
authors.lastname: Yoshioka
authors.forename: Kenzirou
authors.initials: K
authors.lastname: Sawada
authors.forename: Tadashi
authors.initials: T
authors.lastname: Kimura
authors.forename: Norio
authors.initials: N
authors.lastname: Nonomura
mesh_terms: D013734:Androgen-Insensitivity Syndrome / Q000601:surgery*; D005260:Female; D006801:Humans; D010535:Laparoscopy / Q000379:methods*; D008297:Male; D009373:Neoplasms, Germ Cell and Embryonal / Q000473:pathology; D013736:Testicular Neoplasms / Q000473:pathology; D055815:Young Adult