title: Separation of reaction product and palladium catalyst after a Heck coupling reaction by means of organic solvent nanofiltration.
abstract: Organic solvent nanofiltration (OSN) is a recently commercialized technology, which we have used to develop a method for the separation of a target product and the Pd catalyst from a Heck coupling postreaction mixture. The experimental setup included commercially available polyimide copolymer membranes with molecular weight cut-off (MWCO) values in the range of 150-300 Da, acetone as the solvent, and a working pressure (N(2)) of 3 MPa. The investigation of the membranes revealed that a membrane with a MWCO of 200 Da provided quantitative retention of the Pd catalyst and quantitative recovery of the target product by means of a cross-flow dia-nanofiltration procedure.
authors.affiliation: Department of Chemistry, University of Bergen, Bergen, Norway.
authors.forename: Anna
authors.initials: A
authors.lastname: Tsoukala
authors.forename: Ludmila
authors.initials: L
authors.lastname: Peeva
authors.forename: Andrew G
authors.initials: AG
authors.lastname: Livingston
authors.forename: Hans-René
authors.initials: HR
authors.lastname: Bjørsvik
mesh_terms: D002384:Catalysis; D005374:Filtration / Q000379:methods*; D007536:Isomerism; D036103:Nanotechnology / Q000379:methods*; D009930:Organic Chemicals / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*; D012997:Solvents / Q000737:chemistry*
chemical_list: D009930:Organic Chemicals; D012997:Solvents; D010165:Palladium