title: Improving validation practices in "omics" research.
abstract: "Omics" research poses acute challenges regarding how to enhance validation practices and eventually the utility of this rich information. Several strategies may be useful, including routine replication, public data and protocol availability, funding incentives, reproducibility rewards or penalties, and targeted repeatability checks.
authors.affiliation: Stanford Prevention Research Center, Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.
authors.forename: John P A
authors.initials: JP
authors.lastname: Ioannidis
authors.forename: Muin J
authors.initials: MJ
authors.lastname: Khoury
mesh_terms: D022126:Access to Information; D035843:Biomedical Research / Q000592:standards*; D019295:Computational Biology; D016208:Databases, Factual; D036281:Genetic Research; D023281:Genomics; D006801:Humans; D055432:Metabolomics; D040901:Proteomics; D011643:Publishing; D015203:Reproducibility of Results; D059467:Transcriptome; D054928:Validation Studies as Topic