title: neXtProt: a knowledge platform for human proteins.
abstract: neXtProt (http://www.nextprot.org/) is a new human protein-centric knowledge platform. Developed at the Swiss Institute of Bioinformatics (SIB), it aims to help researchers answer questions relevant to human proteins. To achieve this goal, neXtProt is built on a corpus containing both curated knowledge originating from the UniProtKB/Swiss-Prot knowledgebase and carefully selected and filtered high-throughput data pertinent to human proteins. This article presents an overview of the database and the data integration process. We also lay out the key future directions of neXtProt that we consider the necessary steps to make neXtProt the one-stop-shop for all research projects focusing on human proteins.
authors.affiliation: CALIPHO Group, Swiss Institute of Bioinformatics, CMU - 1, Rue Michel Servet 1211 Geneva 4, Switzerland.
authors.forename: Lydie
authors.initials: L
authors.lastname: Lane
authors.forename: Ghislaine
authors.initials: G
authors.lastname: Argoud-Puy
authors.forename: Aurore
authors.initials: A
authors.lastname: Britan
authors.forename: Isabelle
authors.initials: I
authors.lastname: Cusin
authors.forename: Paula D
authors.initials: PD
authors.lastname: Duek
authors.forename: Olivier
authors.initials: O
authors.lastname: Evalet
authors.forename: Alain
authors.initials: A
authors.lastname: Gateau
authors.forename: Pascale
authors.initials: P
authors.lastname: Gaudet
authors.forename: Anne
authors.initials: A
authors.lastname: Gleizes
authors.forename: Alexandre
authors.initials: A
authors.lastname: Masselot
authors.forename: Catherine
authors.initials: C
authors.lastname: Zwahlen
authors.forename: Amos
authors.initials: A
authors.lastname: Bairoch
mesh_terms: D030562:Databases, Protein; D006801:Humans; D051188:Knowledge Bases; D011506:Proteins / Q000235:genetics / Q000378:metabolism; D014584:User-Computer Interface
chemical_list: D011506:Proteins