title: An interrupted Ugi reaction enables the preparation of substituted indoxyls and aminoindoles.
abstract: In a variation of the classical Ugi reaction, an acid promoted reaction between imines and isocyanides forms both 3-aminoindoles and substituted indoxyls. A recently reported triflyl phosphoramide is shown to be critical to obtain high yields under mild conditions.
authors.affiliation: Department of Chemistry, Princeton University, Frick Chemical Laboratory, Princeton NJ 08544.
authors.forename: John S
authors.initials: JS
authors.lastname: Schneekloth
authors.forename: Jimin
authors.initials: J
authors.lastname: Kim
authors.forename: Erik J
authors.initials: EJ
authors.lastname: Sorensen