title: Acaricidal activity of hydroethanolic formulations of thymol against Rhipicephalus sanguineus (Acari: Ixodidae) and Dermacentor nitens (Acari: Ixodidae) larvae.
abstract: The aim of this study was to assess the acaricidal activity of hydroethanolic formulations of thymol at varying concentrations on Rhipicephalus sanguineus and Dermacentor nitens larvae. The larval packet test was used and the thymol concentrations tested were 2.5, 5.0, 10.0, 15.0 and 20.0 mg/ml. The control group was exposed only to water and ethanol (50/50%) and there were 10 repetitions for each treatment. The mortality was evaluated after 24 h. For the R. sanguineus larvae, the mortality rates were 47.5, 50.2, 96.7, 95.9 and 98.1%, while for D. nitens the rates were 14.1, 75.0, 90.2, 90.3 and 99.5%, at respective thymol concentrations of 2.5, 5.0, 10.0, 15.0 and 20.0 mg/ml. The results indicate that the hydroethanolic formulations of thymol tested have acaricidal activity on R. sanguineus and D. nitens larvae exposed topically, causing mortality greater than 90% 24 h post-treatment starting at the concentration of 10 mg/ml.
authors.affiliation: Universidade Federal de Juiz de Fora, Rua José Lourenço Kelmer, s/n - Campus Universitário Bairro Martelos, 36036-330, Juiz de Fora, MG, Brazil.
authors.forename: Erik
authors.initials: E
authors.lastname: Daemon
authors.forename: Ralph
authors.initials: R
authors.lastname: Maturano
authors.forename: Caio Márcio de Oliveira
authors.initials: CM
authors.lastname: Monteiro
authors.forename: Márcio Scoralik
authors.initials: MS
authors.lastname: Goldner
authors.forename: Tainara
authors.initials: T
authors.lastname: Massoni
mesh_terms: D056810:Acaricides / Q000737:chemistry / Q000494:pharmacology*; D000818:Animals; D002626:Chemistry, Pharmaceutical; D004305:Dose-Response Relationship, Drug; D026863:Ixodidae / Q000187:drug effects*; D007814:Larva / Q000187:drug effects; D013943:Thymol / Q000737:chemistry / Q000494:pharmacology*
chemical_list: D056810:Acaricides; D013943:Thymol