title: Prevalence of colorectal polyps in pediatric colonoscopy.
abstract: BACKGROUND
  The available data regarding the prevalence, types, and clinical determinants of colonic polyps in children is limited.
  
  
  OBJECTIVE
  We aimed to estimate the prevalence of colorectal polyps in a large cohort of children.
  
  
  METHODS
  We conducted a cross-sectional study to determine the presence, number, and location of colorectal polyps reported in all children (0-20 years) who underwent colonoscopy at 14 pediatric facilities between January 2000 and December 2007 recorded in Pediatric Endoscopy Database System Clinical Outcomes Research Initiative (PEDS-CORI). We compared procedures with and without polyps with respect to procedure indication, age, sex, and race. We also reviewed a sample of histopathologic reports from one participating center.
  
  
  RESULTS
  We analyzed 13,115 colonoscopy procedures performed in 11,637 patients. Colorectal polyps were reported in 810 procedures (6.1%; 95% CI: 5.7-6.5%) performed in 705 patients, and in 12% of patients with lower GI bleeding. Children with colorectal polyps were significantly younger (8.9 years vs. 11.9 years; p < 0.0001), male (58.3% vs. 49.0%; p < 0.001), non-white race (27.5% vs. 21.9%; p < 0.001), and had lower GI bleeding (54.4% vs. 26.6%; p < 0.001) as compared to children without polyps. In a sample of 122 patients with polyps from a single center, the histological types were solitary juvenile in 91 (70.5%), multiple juvenile in 20 (15.5%), adenoma in 14 (10.9%) and hyperplastic polyps in four patients (3.1%).
  
  
  CONCLUSIONS
  Colorectal polyps are detected in 6.1% overall and in 12.0% among those with lower gastrointestinal bleeding during pediatric colonoscopy. Approximately 26% are multiple juvenile or adenoma.
authors.affiliation: The Section of Pediatric Gastroenterology, Hepatology and Nutrition, Texas Children's Hospital and Baylor College of Medicine, 6621 Fannin St CCC 1010, Houston, TX 77030, USA. kthakkar@bcm.tmc.edu
authors.forename: Kalpesh
authors.initials: K
authors.lastname: Thakkar
authors.forename: Abeer
authors.initials: A
authors.lastname: Alsarraj
authors.forename: Emily
authors.initials: E
authors.lastname: Fong
authors.forename: Jennifer L
authors.initials: JL
authors.lastname: Holub
authors.forename: Mark A
authors.initials: MA
authors.lastname: Gilger
authors.forename: Hashem B
authors.initials: HB
authors.lastname: El Serag
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D003111:Colonic Polyps / Q000175:diagnosis* / Q000453:epidemiology; D003113:Colonoscopy; D005260:Female; D006801:Humans; D007223:Infant; D007417:Intestinal Polyps / Q000175:diagnosis* / Q000453:epidemiology; D008297:Male; D015995:Prevalence; D012002:Rectal Diseases / Q000175:diagnosis* / Q000453:epidemiology; D055815:Young Adult