title: Bactericidal activity of grass carp Ctenopharyngodon idella C9-deficient serum against Aeromonas hydrophila.
abstract: Neutralizing complement C9 in grass carp Ctenopharyngodon idella sera with rabbit anti-C9 sera against fish complement C9, demonstrated that bactericidal activity against Aeromonas hydrophila of the C9-deficient fish sera was greatly impaired. These results indicated that the fish complement C9 plays a key role in pathogen killing through the lytic pathway.
authors.affiliation: State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, PR China.
authors.forename: C
authors.initials: C
authors.lastname: Ji
authors.forename: A H
authors.initials: AH
authors.lastname: Li
authors.forename: J
authors.initials: J
authors.lastname: Xie
authors.forename: D F
authors.initials: DF
authors.lastname: Zhang
authors.forename: J Y
authors.initials: JY
authors.lastname: Liu
mesh_terms: D016980:Aeromonas hydrophila / Q000502:physiology*; D000818:Animals; D001770:Blood Bactericidal Activity; D002347:Carps / Q000276:immunology* / Q000382:microbiology; D003186:Complement C9 / Q000037:antagonists & inhibitors / Q000276:immunology*; D007106:Immune Sera / Q000378:metabolism
chemical_list: D003186:Complement C9; D007106:Immune Sera