title: [Rapid sequence induction in a patient with Steinert myotonic dystrophy: Interest of the association of high doses of rocuronium and sugammadex].
abstract: We report in this clinical case the successful use of a combination of rocuronium and sugammadex in a patient with Steinert myotonic dystrophy to perform a rapid sequence induction of anaesthesia. The patient had both contraindication to succinylcholine and a risk of prolonged neuromuscular blockade with non-depolarizing neuromuscular blocking agents. The use of high dose rocuronium (1mg/kg) allowed a quick and easy orotracheal intubation but induced a prolonged neuromuscular block, reversed with success by sugammadex (8 mg/kg).
authors.affiliation: Service d'anesthésie réanimation, hôpital de Timone, CHU Timone, AP-HM, 264, rue Saint-Pierre, 13385 Marseille, France. lionel.pellegrini@ap-hm.fr
authors.forename: L
authors.initials: L
authors.lastname: Pellegrini
authors.forename: M-F
authors.initials: MF
authors.lastname: Mercier
authors.forename: A
authors.initials: A
authors.lastname: Cornese
authors.forename: V
authors.initials: V
authors.lastname: Blasco
authors.forename: J
authors.initials: J
authors.lastname: Albanèse
mesh_terms: D000328:Adult; D000732:Androstanols / Q000008:administration & dosage*; D000758:Anesthesia / Q000379:methods*; D004359:Drug Therapy, Combination; D006801:Humans; D008297:Male; D009223:Myotonic Dystrophy; D003473:Neuromuscular Nondepolarizing Agents / Q000008:administration & dosage*; D000077123:Rocuronium; D000077122:Sugammadex; D013997:Time Factors; D047408:gamma-Cyclodextrins / Q000008:administration & dosage*
chemical_list: D000732:Androstanols; D003473:Neuromuscular Nondepolarizing Agents; D047408:gamma-Cyclodextrins; D000077122:Sugammadex; D000077123:Rocuronium