title: Amine-functionalized lanthanide-doped KGdF4 nanocrystals as potential optical/magnetic multimodal bioprobes.
abstract: Amine-functionalized lanthanide-doped KGdF(4) nanocrystals, synthesized via a facile one-step solvothermal route by employing polyethylenimine as the surfactant and capping ligand, have been demonstrated to be sensitive time-resolved FRET bioprobes to detect a trace amount of biomolecules such as avidin at a concentration of 5.5 nM and to be potential T(1)-MRI contrast agents due to a large longitudinal relaxivity of Gd(3+) (5.86 S(-1)·mM(-1) per Gd ion and 3.99 × 10(5) S(-1)·mM(-1) per nanocrystal).
authors.affiliation: Key Laboratory of Optoelectronic Materials Chemistry and Physics, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, Fujian 350002, China.
authors.forename: Qiang
authors.initials: Q
authors.lastname: Ju
authors.forename: Datao
authors.initials: D
authors.lastname: Tu
authors.forename: Yongsheng
authors.initials: Y
authors.lastname: Liu
authors.forename: Renfu
authors.initials: R
authors.lastname: Li
authors.forename: Haomiao
authors.initials: H
authors.lastname: Zhu
authors.forename: Jincan
authors.initials: J
authors.lastname: Chen
authors.forename: Zhuo
authors.initials: Z
authors.lastname: Chen
authors.forename: Mingdong
authors.initials: M
authors.lastname: Huang
authors.forename: Xueyuan
authors.initials: X
authors.lastname: Chen
mesh_terms: D000588:Amines / Q000737:chemistry*; D001360:Avidin / Q000737:chemistry; D003287:Contrast Media / Q000737:chemistry*; D016650:Fluorescein-5-isothiocyanate / Q000031:analogs & derivatives / Q000737:chemistry; D028581:Lanthanoid Series Elements / Q000737:chemistry*; D008027:Light; D049449:Luminescence; D060328:Magnetic Phenomena; D008279:Magnetic Resonance Imaging; D053758:Nanoparticles / Q000737:chemistry*; D017680:Potassium Compounds / Q000737:chemistry*
chemical_list: D000588:Amines; D003287:Contrast Media; D028581:Lanthanoid Series Elements; D017680:Potassium Compounds; C036963:fluorescein isothiocyante avidin; D001360:Avidin; D016650:Fluorescein-5-isothiocyanate