title: Slack brain in meningioma surgery through lateral supraorbital approach.
abstract: BACKGROUND
  Surgery of skull base meningiomas by the lateral supraorbital (LSO) approach requires relaxed brain. Therefore, we assessed combined effects of the elements of neuroanesthesia on neurosurgical conditions during craniotomy.
  
  
  METHODS
  The anesthesiological and surgical charts of 66 olfactory groove, 73 anterior clinoidal, and 52 tuberculum sellae meningioma patients operated on by the senior author (J.H.) at the Department of Neurosurgery of Helsinki University Central Hospital, Helsinki, Finland, between September 1997 and August 2010, were retrospectively analyzed.
  
  
  RESULTS
  One-hundred fifty-four (82%) patients had good surgical conditions, and this was achieved by (1) elevating the head 20 cm above the cardiac level in all patients with only slightly lateral turn or neck flexion, (2) administering mannitol preoperatively in medium or large meningiomas (n = 60), (3) maintaining anesthesia with propofol infusion (n = 46) or volatile anesthetics (n = 107) also in patients with large tumors (n = 37), and (4) controlling intraoperative hemodynamics. Brain relaxation was satisfactory in 18 (10%) and poor in 15 (8%) patients. The median intraoperative blood loss was 200 (range, 0-2000) ml. Only 9% of patients received red blood cell transfusion. The median time to extubation was 18 (range, 8-105) min after surgery. Extubation time correlated with the patients' preoperative clinical status and the size of tumor but not with the modality of anesthesia.
  
  
  CONCLUSIONS
  Slack brain during the LSO approach is achieved by correct patient positioning, preoperative mannitol, either by propofol or in small tumors inhaled anesthetics, and optimizing cerebral perfusion pressure. Under these circumstances, intraoperative brain swelling is prevented, bleeding is minimal, and no blood transfusions are needed.
authors.affiliation: Department of Neurosurgery, Helsinki University Central Hospital, Helsinki, Finland.
authors.forename: Rossana
authors.initials: R
authors.lastname: Romani
authors.forename: Marja
authors.initials: M
authors.lastname: Silvasti-Lundell
authors.forename: Aki
authors.initials: A
authors.lastname: Laakso
authors.forename: Hanna
authors.initials: H
authors.lastname: Tuominen
authors.forename: Juha
authors.initials: J
authors.lastname: Hernesniemi
authors.forename: Tomi
authors.initials: T
authors.lastname: Niemi