title: [Effect of different porcelain-fused-to-metal crown inner metal materials on the level of soluble intercellular adhesion molecule-1 and interleukin-1beta in gingival crevicular fluid].
abstract: OBJECTIVE
  To investigate the effect of different inner metal materials of porcelain-fused-to-metal (PFM) crown on periodontal tissue by means of measuring the level of soluble intercellular adhesion molecule-1 (sICAM-1) and interleukin-1beta (IL-1beta) in gingival crevicular fluid (GCF) after PFM restorations.
  
  
  METHODS
  30 teeth were divided into three groups (Ni-Cr alloy group, Co-Cr alloy group and Au-Pt alloy group, 10 teeth each group), and restored by Ni-Cr alloy, Co-Cr alloy and Au-Pt alloy PFM crown according grouping. At the point of pre-restoration, 6-month and 12-month after cementation, the clinical parameters including plaque index (PLI), gingival index (GI) and gingival crevice depth (GCD) were detected, and GCF was collected from labial and lingual of mesial site and distal site. The level of sICAM-1 and IL-1beta were detected.
  
  
  RESULTS
  At the point of 6-month and 12-month after cementation, Ni-Cr alloy group showed significant difference for GI, GCD and all GCF indexes when compared to pre-restoration, Co-Cr alloy group and Au-Pt alloy group (P < 0.05). At the point of 12-month after cementation, Co-Cr alloy group showed significant difference for GI, GCD and all GCF indexes when compared to pre-restoration and Au-Pt alloy group (P < 0.05). All indexes have no significant difference for Au-Pt alloy group during the 12-month experiment times when compared to pre-restoration (P > 0.05).
  
  
  CONCLUSIONS
  Non-noble metal has bad effect on the periodontal tissue.
authors.affiliation: Dept. of Prosthodontics, School of Stomatology, Weifang Medical College, Weifang 261042, China.
authors.forename: Tangxia
authors.initials: T
authors.lastname: Yuan
authors.forename: Yanbiao
authors.initials: Y
authors.lastname: Zhang
authors.forename: Zheng-Hua
authors.initials: ZH
authors.lastname: Wu
mesh_terms: D002858:Chromium Alloys; D003442:Crowns; D003776:Dental Porcelain; D005881:Gingiva; D005883:Gingival Crevicular Fluid; D006801:Humans; D018799:Intercellular Adhesion Molecule-1; D053583:Interleukin-1beta; D016876:Metal Ceramic Alloys; D010512:Periodontal Index
chemical_list: D002858:Chromium Alloys; D053583:Interleukin-1beta; D016876:Metal Ceramic Alloys; D003776:Dental Porcelain; D018799:Intercellular Adhesion Molecule-1