title: Factors Affecting EWS-FLI1 Activity in Ewing's Sarcoma.
abstract: Ewing's sarcoma family tumors (ESFT) are characterized by specific chromosomal translocations, which give rise to EWS-ETS chimeric proteins. These aberrant transcription factors are the main pathogenic drivers of ESFT. Elucidation of the factors influencing EWS-ETS expression and/or activity will guide the development of novel therapeutic agents against this fatal disease.
authors.affiliation: Children's Cancer Research Institute, St Anna Kinderkrebsforschung, 1090 Vienna, Austria.
authors.forename: David
authors.initials: D
authors.lastname: Herrero-Martin
authors.forename: Argyro
authors.initials: A
authors.lastname: Fourtouna
authors.forename: Stephan
authors.initials: S
authors.lastname: Niedan
authors.forename: Lucia T
authors.initials: LT
authors.lastname: Riedmann
authors.forename: Raphaela
authors.initials: R
authors.lastname: Schwentner
authors.forename: Dave N T
authors.initials: DN
authors.lastname: Aryee