title: Current evidence in therapeutic hypothermia for postcardiac arrest care.
abstract: The ring of the red notification phone breaks the relative calm of an otherwise typical Monday morning and heralds the arrival of a critically ill patient. The dispatcher announces that EMS is on the way with a 57-year-old man in cardiac arrest, with an ETA of 3 minutes. Shortly after preparations for their arrival are complete, EMS personnel enter with CPR in progress and the patient already intubated. As monitor/defibrillator attachment, ETT placement confirmation, additional IV access, and complete exposure of the patient occur, you hear more about the clinical scenario from EMS. Mr. I.C. is a 57-year-old male who was moving furniture when, as described by witnesses, he complained of difficulty catching his breath and a slight tightness in his chest. He began coughing violently, vomited once, gasped, and collapsed. Emergency medical services personnel state that they arrived approximately 20 minutes after the patient had collapsed, with CPR in progress. The patient was intubated in the field, and EMS reports that the initial rhythm was PEA. Upon the patient's arrival in the ED, the rhythm is noted to be ventricular fibrillation. Defibrillation is attempted twice over the next 4 minutes, with concomitant administration of medications. During the next rhythm check, QRS complexes are noted on the monitor and a pulse is palpated. The patient has had a return of spontaneous circulation, apparently 50 minutes from onset of the arrest. As you initiate postresuscitation care, you consider the patient's prognosis and wonder if he qualifies for therapeutic hypothermia; ie, will therapeutic hypothermia make a difference in his outcome?
authors.affiliation: Department of Emergency Medicine, State University of New York, Downstate/Kings County Hospital, Brooklyn, NY, USA.
authors.forename: Matthew
authors.initials: M
authors.lastname: Constantine
mesh_terms: D000818:Animals; D002545:Brain Ischemia; D003362:Cost-Benefit Analysis; D003422:Critical Care / Q000379:methods*; D019091:Critical Pathways; D003937:Diagnosis, Differential; D019468:Disease Management; D019317:Evidence-Based Medicine; D006439:Hemodynamics; D006801:Humans; D007036:Hypothermia, Induced / Q000191:economics / Q000379:methods; D008297:Male; D008833:Microcirculation; D008875:Middle Aged; D008991:Monitoring, Physiologic; D058687:Out-of-Hospital Cardiac Arrest / Q000191:economics / Q000628:therapy*; D017410:Practice Guidelines as Topic; D011379:Prognosis; D012308:Risk Management