title: Rhodium(III)-catalyzed intermolecular direct amination of aromatic C-H bonds with N-chloroamines.
abstract: A Rh(III)-catalyzed direct aromatic C-H amination is achieved using N-chloroamines as a reagent. Furthermore, we also developed a one-pot amination protocol involving in situ chlorination of the secondary amines. The catalytic amination operates at mild conditions with excellent functional group tolerance and regioselectivity.
authors.affiliation: State Key Laboratory for Chirosciences and The Open Laboratory for Chirotechnology of the Institute of Molecular Technology for Drug Discovery and Synthesis, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Hong Kong.
authors.forename: Ka-Ho
authors.initials: KH
authors.lastname: Ng
authors.forename: Zhongyuan
authors.initials: Z
authors.lastname: Zhou
authors.forename: Wing-Yiu
authors.initials: WY
authors.lastname: Yu
mesh_terms: D000586:Amination; D002244:Carbon / Q000737:chemistry*; D002384:Catalysis; D002700:Chloramines / Q000737:chemistry*; D006859:Hydrogen / Q000737:chemistry*; D015394:Molecular Structure; D012238:Rhodium / Q000737:chemistry*
chemical_list: D002700:Chloramines; D002244:Carbon; D006859:Hydrogen; D012238:Rhodium