title: Reversible progressive supranuclear palsy-like phenotype as an initial manifestation of HIV infection.
abstract: Movement disorders are common manifestations of human immunodeficiency virus (HIV) infection, and may sometimes be the initial manifestations of HIV infection. Although secondary progressive supranuclear palsy (PSP) due to factors such as paraneoplastic, vascular, and hypoxic-ischemic injury have been reported, PSP associated with HIV infection has received little attention. We describe a patient who displayed a progressive parkinsonian phenotype fulfilling the criteria for PSP over a period of a year. The parkinsonism was the initial manifestation of HIV infection and was eliminated by highly active antiretroviral therapy. This case report indicates that one should consider HIV infection as a cause of PSP-like parkinsonism.
authors.affiliation: Department of Neurology, College of Medicine, Hanyang University, 17 Haengdangdong, Seongdong-gu, Seoul 133-792, Korea.
authors.forename: Wooyoung
authors.initials: W
authors.lastname: Jang
authors.forename: Joong-Seok
authors.initials: JS
authors.lastname: Kim
authors.forename: Jin Young
authors.initials: JY
authors.lastname: Ahn
authors.forename: Hee-Tae
authors.initials: HT
authors.lastname: Kim
mesh_terms: D000368:Aged; D023241:Antiretroviral Therapy, Highly Active; D015658:HIV Infections / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D010641:Phenotype; D013494:Supranuclear Palsy, Progressive / Q000209:etiology* / Q000473:pathology