title: New medications for substance use disorders: challenges and opportunities.
abstract: An increased understanding of the biological mechanisms underlying the process of addiction has led to unique molecular targets and strategies for pharmacotherapies against addiction. However, the successful translation of these discoveries will require: 1) a more active engagement of the pharmaceutical sector, 2) partnership with regulatory agencies to arrive at meaningful outcomes for medication approval and 3) a greater involvement of the healthcare system in the screening and treatment of substance use disorders.
authors.affiliation: National Institute on Drug Abuse, Bethesda, MD 20892, USA. nvolkow@nida.nih.gov
authors.forename: Nora D
authors.initials: ND
authors.lastname: Volkow
authors.forename: Phil
authors.initials: P
authors.lastname: Skolnick
mesh_terms: D000818:Animals; D015195:Drug Design; D005544:Forecasting; D006801:Humans; D009316:National Institutes of Health (U.S.) / Q000639:trends*; D011600:Psychopharmacology / Q000639:trends*; D019966:Substance-Related Disorders / Q000188:drug therapy*; D014481:United States