title: Effects of a phosphodiesterase inhibitor (Rolipram) on the urinary excretion of 6-sulphatoxy melatonin in man.
abstract: The urinary excretion of 6-sulphatoxymelatonin (aMT6s) from 2400 to 0600 h was significantly increased following the treatment of ten normal volunteers with a phospho diesterase inhibitor (rolipram 1 mg 8 h for 24 h). The urinary excretion of the metabolite from 0600 to 1200 h was significantly reduced after treatment with rolipram.
authors.affiliation: Maudsley Hospital, Denmark Hill, London, SE5.
authors.forename: S A
authors.initials: SA
authors.lastname: Checkley
authors.forename: F
authors.initials: F
authors.lastname: Winton
authors.forename: T
authors.initials: T
authors.lastname: Corn
authors.forename: C
authors.initials: C
authors.lastname: Franey
authors.forename: J
authors.initials: J
authors.lastname: Arendt