title: Palladium-catalyzed direct arylation of polysubstituted benzofurans.
abstract: An efficient access to 2-substituted 3-arylbenzofurans through a palladium-catalyzed C3 direct arylation of 2-substituted benzofurans with aryl bromides is described. The scope and limitation of this reaction was studied. The method tolerates a variety of functional groups on the aryl halide and has been successfully extended to polysubstituted benzofurans to obtain the corresponding 3-arylbenzofurans with good to excellent yields.
authors.affiliation: CNRS UMR 176, 26 rue d'Ulm, 75248 Paris, France.
authors.forename: Amandine
authors.initials: A
authors.lastname: Carrër
authors.forename: Dimitri
authors.initials: D
authors.lastname: Brinet
authors.forename: Jean-Claude
authors.initials: JC
authors.lastname: Florent
authors.forename: Patricia
authors.initials: P
authors.lastname: Rousselle
authors.forename: Emmanuel
authors.initials: E
authors.lastname: Bertounesque
mesh_terms: D001572:Benzofurans / Q000737:chemistry*; D002384:Catalysis; D004579:Electron Transport; D010165:Palladium / Q000737:chemistry*
chemical_list: D001572:Benzofurans; D010165:Palladium