title: Bio-based production of chemicals, materials and fuels -Corynebacterium glutamicum as versatile cell factory.
abstract: Since their discovery almost 60 years ago, Corynebacterium glutamicum and related subspecies are writing a remarkable success story in industrial biotechnology. Today, these gram-positive soil bacteria, traditionally well-known as excellent producers of L-amino acids are becoming flexible, efficient production platforms for various chemicals, materials and fuels. This development is intensively driven by systems metabolic engineering concepts integrating systems biology and synthetic biology into strain engineering.
authors.affiliation: Institute of Biochemical Engineering, Technische Universität Braunschweig, Gaußstraße 17, 38106 Braunschweig, Germany.
authors.forename: Judith
authors.initials: J
authors.lastname: Becker
authors.forename: Christoph
authors.initials: C
authors.lastname: Wittmann
mesh_terms: D000596:Amino Acids / Q000096:biosynthesis / Q000378:metabolism; D056804:Biofuels; D001709:Biotechnology; D048230:Corynebacterium glutamicum / Q000235:genetics / Q000378:metabolism*; D005818:Genetic Engineering; D060847:Metabolic Engineering; D058615:Synthetic Biology / Q000379:methods*; D049490:Systems Biology
chemical_list: D000596:Amino Acids; D056804:Biofuels