title: Hypertension and symptomatic hypokalemia in a patient with simultaneous unilateral stenoses of intrarenal arteries and mesangioproliferative glomerulonephritis.
abstract: We present the case of a young patient with hypertension and unprovoked symptomatic hypokalemia. His workup uncovered secondary aldosteronism, moderate proteinuria, and, quite unusually, concurrent chronic hepatitis B. Detailed investigations, including renal angiography, renal vein sampling, and kidney biopsy, showed unilateral renin hypersecretion due to intrarenal arterial stenoses and mesangioproliferative glomerulonephritis, presumed to be secondary to hepatitis B infection. Targeted pharmacotherapy reversed all clinical manifestations, normalizing blood pressure and serum potassium level and achieving full remission of proteinuria and loss of hepatitis B surface antigen (HBsAg) and hepatitis B e antigen (HBeAg), and a dramatic decrease in viral load.
authors.affiliation: Section of Nephrology and Hypertension, First Department of Medicine, AHEPA Hospital, Aristotle University of Thessaloniki, Greece. psarafidis11@yahoo.gr
authors.forename: Pantelis A
authors.initials: PA
authors.lastname: Sarafidis
authors.forename: Panagiotis I
authors.initials: PI
authors.lastname: Georgianos
authors.forename: Georgios
authors.initials: G
authors.lastname: Germanidis
authors.forename: Constantinos
authors.initials: C
authors.lastname: Giavroglou
authors.forename: Pavlos
authors.initials: P
authors.lastname: Nikolaidis
authors.forename: Anastasios N
authors.initials: AN
authors.lastname: Lasaridis
authors.forename: Nicolaos E
authors.initials: NE
authors.lastname: Madias
mesh_terms: D000328:Adult; D015432:Glomerulonephritis, Membranoproliferative / Q000150:complications* / Q000821:virology; D019694:Hepatitis B, Chronic / Q000150:complications; D006801:Humans; D006973:Hypertension / Q000150:complications*; D007008:Hypokalemia / Q000150:complications*; D008297:Male; D012078:Renal Artery Obstruction / Q000150:complications*