title: [Screening and characteristics of regulators of landomycin E biosynthesis in Streptomyces globisporus].
abstract: The screening of the positive regulators of landomycin E biosynthesis has been conducted among exogenous metabolites of the museum and freshly isolated Streptomycetes strains by means of cosynthesis test using mutant strain Streptomyces globisporus 1912-82. The ability to produce the exogenous metabolites restoring landomycin E biosynthesis by B2 strain was shown. The regulatory compounds purified by thin-layer chromatography differed between themselves by chromatographic mobility (Rf) and maxima of absorption in UV-light. They were divided into four types of extracellular regulators of landomycin E biosynthesis on the basis of preliminary study.
authors.forename: B P
authors.initials: BP
authors.lastname: Matseliukh
authors.forename: S H
authors.initials: SH
authors.lastname: Tymoshenko
authors.forename: O I
authors.initials: OI
authors.lastname: Bambura
authors.forename: O P
authors.initials: OP
authors.lastname: Kopeĭko
mesh_terms: D000617:Aminoglycosides / Q000096:biosynthesis*; D000900:Anti-Bacterial Agents / Q000096:biosynthesis*; D001426:Bacterial Proteins / Q000235:genetics / Q000302:isolation & purification / Q000378:metabolism*; D002855:Chromatography, Thin Layer; D009154:Mutation; D013302:Streptomyces / Q000235:genetics / Q000378:metabolism*
chemical_list: D000617:Aminoglycosides; D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; C113593:landomycin E