title: Successful engraftment and survival following allogeneic hematopoietic stem cell transplant in a child with familial hemophagocytic lymphohistiocytosis.
abstract: Hemophagocytic syndrome is a rare disorder mainly affecting children. Symptoms include prolonged fever, hepatosplenomegaly and cytopenias. Allogeneic stem cell transplant appears to provide the best overall cure rate in this disease. The authors report a young boy, the second child of consanguineous parents, diagnosed with familial hemophagocytic lymphohistiocytosis (HLH) who underwent allogeneic stem cell transplant form HLA matched father.
authors.affiliation: Section of Hematology, Department of Pathology and Microbiology, The Aga Khan University and Hospital, Stadium Road 74800, P O Box 3500, Karachi, Pakistan. natasha.ali@aku.edu
authors.forename: Natasha
authors.initials: N
authors.lastname: Ali
authors.forename: Zehra
authors.initials: Z
authors.lastname: Fadoo
authors.forename: Nehal
authors.initials: N
authors.lastname: Masood
authors.forename: Salman Naseem
authors.initials: SN
authors.lastname: Adil
mesh_terms: D001853:Bone Marrow / Q000601:surgery*; D002648:Child; D002675:Child, Preschool; D018380:Hematopoietic Stem Cell Transplantation / Q000379:methods* / Q000401:mortality; D006801:Humans; D051359:Lymphohistiocytosis, Hemophagocytic / Q000188:drug therapy / Q000401:mortality / Q000628:therapy*; D008297:Male; D015996:Survival Rate; D014184:Transplantation, Homologous; D016896:Treatment Outcome