title: Adult stem cells: simply a tool for regenerative medicine or an additional piece in the puzzle of human aging?
abstract: Adult stem cells have taken center stage in current research related to regenerative medicine and pharmacogenomic studies seeking new therapeutic interventions. As we learn more about these cells, it is becoming apparent that the next big leap in our understanding of adult stem cell biology and adult stem cell aging will depend on the integration of approaches from various disciplines. Major advances and technological breakthroughs at the crossroad of fields such as biomaterials, genomics, epigenomics, and proteomics will enable the design of better tools to model human diseases, and warrant safe usage of adult stem cells in the clinic.
authors.affiliation: Buck Institute for Age Research, Novato, CA, USA.
authors.forename: James R
authors.initials: JR
authors.lastname: Tollervey
authors.forename: Victoria V
authors.initials: VV
authors.lastname: Lunyak
mesh_terms: D053687:Adult Stem Cells / Q000502:physiology*; D000375:Aging / Q000502:physiology*; D002454:Cell Differentiation / Q000502:physiology; D019070:Cell Lineage / Q000502:physiology; D006801:Humans; D008954:Models, Biological; D044968:Regenerative Medicine / Q000379:methods* / Q000639:trends; D012106:Research / Q000639:trends*