title: Drug delivery and imaging with polydiacetylene micelles.
abstract: This concept article summarizes our recent findings regarding photopolymerized micelles obtained from the self-assembly of diacetylene-containing amphiphiles. Their synthesis and characterization are presented as well as some biomedical applications, such as tumor imaging and drug delivery. Finally, ongoing studies and future challenges are briefly discussed.
authors.affiliation: CEA, iBiTecS, Service de Chimie Bioorganique et de Marquage, 91191 Gif-sur-Yvette, France. edmond.gravel@cea.fr
authors.forename: Edmond
authors.initials: E
authors.lastname: Gravel
authors.forename: Julien
authors.initials: J
authors.lastname: Ogier
authors.forename: Thomas
authors.initials: T
authors.lastname: Arnauld
authors.forename: Nicolas
authors.initials: N
authors.lastname: Mackiewicz
authors.forename: Frédéric
authors.initials: F
authors.lastname: Ducongé
authors.forename: Eric
authors.initials: E
authors.lastname: Doris
mesh_terms: D000818:Animals; D016503:Drug Delivery Systems / Q000379:methods*; D006801:Humans; D051379:Mice; D008823:Micelles; D009369:Neoplasms / Q000175:diagnosis*; D009571:Nitrilotriacetic Acid / Q000737:chemistry; D000078789:Polyacetylene Polymer; D011092:Polyethylene Glycols / Q000737:chemistry; D058105:Polymerization; D011108:Polymers / Q000737:chemistry*; D053279:Polyynes / Q000737:chemistry*; D051381:Rats; D013501:Surface-Active Agents / Q000737:chemistry*
chemical_list: D008823:Micelles; D000078789:Polyacetylene Polymer; D011108:Polymers; D013501:Surface-Active Agents; D053279:Polyynes; C082361:polydiacetylene; D011092:Polyethylene Glycols; D009571:Nitrilotriacetic Acid