title: [Surgical treatment of liver metastasis in patients with colorectal cancer].
abstract: Half of patients with colorectal cancer have liver metastasis during their illness. Surgical resection of metastases represents the only curative treatment with prolonged survival in more than 50 % of patients. The aim of liver resection is complete excision of the lesions with histological negative margins while preserving sufficient functional liver parenchyma. In patients with diffuse liver disease, the radiofrequency ablation of metastases may be associated with surgical resection. The use of portal vein remobilization and neoadjuvant chemotherapy can also increase the number of patients for curative treatment. Despite this progress, from 50 to 60 % of patients relapse after complete resection of MHCCR. Surgical treatment of recurrent aggressive and effective chemotherapy allows the prolonged survival of these patients. The modern treatment of liver metastasis of colorectal cancers can be envisaged as part of a multidisciplinary approach to increase the number of patients for curative treatment.
authors.affiliation: AP-HP, hôpital Cochin, université Paris-Descartes, service de chirurgie digestive, hépatobiliaire et endocrinienne, 75679 Paris cedex 14, France.
authors.forename: Mircea
authors.initials: M
authors.lastname: Chirica
authors.forename: Mahaut
authors.initials: M
authors.lastname: Leconte
authors.forename: Olivier
authors.initials: O
authors.lastname: Oberlin
authors.forename: Bertrand
authors.initials: B
authors.lastname: Dousset
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis / Q000401:mortality / Q000473:pathology* / Q000601:surgery*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000627:therapeutic use; D015179:Colorectal Neoplasms / Q000175:diagnosis / Q000401:mortality / Q000473:pathology* / Q000601:surgery*; D003131:Combined Modality Therapy; D006498:Hepatectomy / Q000379:methods / Q000706:statistics & numerical data; D006801:Humans; D008113:Liver Neoplasms / Q000175:diagnosis / Q000401:mortality / Q000556:secondary* / Q000601:surgery*; D018579:Patient Selection; D011379:Prognosis