title: [Th1, Th17 and Th1+17 cells].
abstract: T helper cells contribute to the induction and maintenance of rheumatic inflammation through the secretion of cytokines. The analysis of Th1 cells expressing interferon-γ, Th17 cells expressing interleukin-17 and the newly described Th1+17 cells could give insight into the pathophysiological mechanisms of rheumatic diseases. This could lead to the development of novel, targeted therapeutic strategies.
authors.affiliation: Deutsches Rheuma-Forschungszentrum Berlin, ein Institut der Leibniz-Gemeinschaft, Berlin, Deutschland. chang@drfz.de
authors.forename: H-D
authors.initials: HD
authors.lastname: Chang
authors.forename: T
authors.initials: T
authors.lastname: Kamradt
authors.forename: H
authors.initials: H
authors.lastname: Schulze-Koops
mesh_terms: D000818:Animals; D016207:Cytokines / Q000276:immunology*; D006801:Humans; D007113:Immunity, Innate / Q000276:immunology*; D018448:Models, Immunological; D012216:Rheumatic Diseases / Q000276:immunology* / Q000473:pathology*; D018417:Th1 Cells / Q000276:immunology*; D058504:Th17 Cells / Q000276:immunology*
chemical_list: D016207:Cytokines