title: A case of factor V inhibitor with complete correction of the PT and aPTT upon mixing.
abstract: We read with interest Gartrell's recent report of a woman who developed a factor V inhibitor. Gartrell noted in his report that the inhibitor appeared to exhibit time dependence, as the mixing study showed slightly more prolongation of both the PT and the aPTT after 1 hr than immediately following mixing. We believe Gartrell's article may shed light on a recent intriguing case of a patient with factor V inhibitor at our institution.
authors.affiliation: Division of Hematology/Oncology, Maimonides Medical Center, Brooklyn, NY, USA. jlipshitz@maimonidesmed.org
authors.forename: Jay
authors.initials: J
authors.lastname: Lipshitz
authors.forename: Thandavababu
authors.initials: T
authors.lastname: Chelliah
authors.forename: Louis
authors.initials: L
authors.lastname: Aledort
mesh_terms: D000925:Anticoagulants / Q000009:adverse effects*; D001778:Blood Coagulation Disorders / Q000209:etiology*; D005165:Factor V / Q000037:antagonists & inhibitors*; D005260:Female; D006801:Humans; D014859:Warfarin / Q000009:adverse effects*
chemical_list: D000925:Anticoagulants; D014859:Warfarin; D005165:Factor V