title: A comparative study on dental pulp response to calcium hydroxide, white and grey mineral trioxide aggregate as pulp capping agents.
abstract: BACKGROUND
  Vital pulp therapy has been known as one of the treatment options to preserve pulp after being exposed by trauma or caries.
  
  
  OBJECTIVE
  To investigate human pulpal response to white and grey mineral trioxide aggregate (WMTA, GMTA) and Dycal (MTA) as pulp capping agents.
  
  
  METHODS
  Human volunteers were participated in this randomized clinical trial.
  
  
  METHODS
  This study was conducted on 90 intact first and second premolars of human maxillary and mandibular teeth. The teeth were randomly assigned into three groups of 30 each. Under local anesthesia, teeth were exposed and capped either with GMTA, WMTA, or Dycal. After 30, 60, and 90 days 10 teeth of each group were extracted and prepared for histologic observation.
  
  
  METHODS
  Histopathologic data were analyzed by χ(2), Kruskal Wallis and Mann Whitney tests.
  
  
  RESULTS
  the calcified bridge in teeth that were capped with GMTA was significantly thicker than Dycal at 30 and 60 days (P= 0.015 and P=0.002, respectively); whereas WMTA showed significantly thicker calcified bridge than Dycal at 90 days (P=0.02). In addition, GMTA specimens showed significantly less inflammation compared to Dycal samples at 90 days interval (P=0.019). No significant difference was found between GMTA and WMTA in terms of calcified bridge thickness and pulp inflammatory response to the capping materials (P>0.05).
  
  
  CONCLUSIONS
  Based on the result of this study, both types of MTA can be suggested as the materials of choice for direct pulp capping procedure instead of Dycal as hard setting calcium hydroxide cement.
authors.affiliation: Restorative Dentistry Department, Oral and Dental Diseases Research Center, Kerman, Iran.
authors.forename: Ali
authors.initials: A
authors.lastname: Eskandarizadeh
authors.forename: Mohammad Hossein
authors.initials: MH
authors.lastname: Shahpasandzadeh
authors.forename: Mahdieh
authors.initials: M
authors.lastname: Shahpasandzadeh
authors.forename: Molok
authors.initials: M
authors.lastname: Torabi
authors.forename: Masoud
authors.initials: M
authors.lastname: Parirokh