title: Primary aldosteronism in 2011: Towards a better understanding of causation and consequences.
abstract: With primary aldosteronism now widely acknowledged as common and associated with both hypertension-related and non-hypertension-related pathology, research interest into its causes and consequences continues to grow. In 2011, major breakthroughs occurred in understanding the role and nature of underlying genetic disturbances and elucidating the pathophysiology of its cardiovascular sequelae.
authors.affiliation: Endocrine Hypertension Research Center, University of Queensland School of Medicine, Greenslopes and Princess Alexandra Hospitals, Ipswich Road, Woolloongabba, Brisbane 4102, Australia. m.stowasser@uq.edu.au
authors.forename: Michael
authors.initials: M
authors.lastname: Stowasser
mesh_terms: D000818:Animals; D032882:Comprehension; D004704:Endocrinology / Q000379:methods / Q000639:trends*; D051676:G Protein-Coupled Inwardly-Rectifying Potassium Channels / Q000235:genetics; D020022:Genetic Predisposition to Disease; D006801:Humans; D006929:Hyperaldosteronism / Q000150:complications* / Q000453:epidemiology / Q000209:etiology* / Q000235:genetics; D008954:Models, Biological; D009154:Mutation / Q000502:physiology; D012307:Risk Factors
chemical_list: D051676:G Protein-Coupled Inwardly-Rectifying Potassium Channels; C484274:KCNJ5 protein, human