title: Ultra-wideband sensors for improved magnetic resonance imaging, cardiovascular monitoring and tumour diagnostics.
abstract: The specific advantages of ultra-wideband electromagnetic remote sensing (UWB radar) make it a particularly attractive technique for biomedical applications. We partially review our activities in utilizing this novel approach for the benefit of high and ultra-high field magnetic resonance imaging (MRI) and other applications, e.g., for intensive care medicine and biomedical research. We could show that our approach is beneficial for applications like motion tracking for high resolution brain imaging due to the non-contact acquisition of involuntary head motions with high spatial resolution, navigation for cardiac MRI due to our interpretation of the detected physiological mechanical contraction of the heart muscle and for MR safety, since we have investigated the influence of high static magnetic fields on myocardial mechanics. From our findings we could conclude, that UWB radar can serve as a navigator technique for high and ultra-high field magnetic resonance imaging and can be beneficial preserving the high resolution capability of this imaging modality. Furthermore it can potentially be used to support standard ECG analysis by complementary information where sole ECG analysis fails. Further analytical investigations have proven the feasibility of this method for intracranial displacements detection and the rendition of a tumour's contrast agent based perfusion dynamic. Beside these analytical approaches we have carried out FDTD simulations of a complex arrangement mimicking the illumination of a human torso model incorporating the geometry of the antennas applied.
authors.affiliation: Physikalisch-Technische Bundesanstalt (PTB), Abbe-Str. 2-12, 10587 Berlin, Germany. florian.thiel@ptb.de
authors.forename: Florian
authors.initials: F
authors.lastname: Thiel
authors.forename: Olaf
authors.initials: O
authors.lastname: Kosch
authors.forename: Frank
authors.initials: F
authors.lastname: Seifert
mesh_terms: D015374:Biosensing Techniques / Q000295:instrumentation*; D002320:Cardiovascular Physiological Phenomena; D003198:Computer Simulation; D005240:Feasibility Studies; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000295:instrumentation* / Q000379:methods / Q000592:standards; D008991:Monitoring, Physiologic / Q000295:instrumentation* / Q000379:methods; D009206:Myocardium; D009369:Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging; D011825:Radar / Q000295:instrumentation / Q000706:statistics & numerical data; D011856:Radiographic Image Enhancement / Q000379:methods; D060726:Torso