title: Dual-parameter optimisation of the elastic properties of skin.
abstract: This paper presents a procedure for characterising the mechanical properties of skin using stochastic inverse identification. It is based on the minimisation of a cost function relative to the comparison between experimental suction experiments and their corresponding finite element models. Two different models are compared: a classical single-layer approach and a dual-layer medium which account for both the dermis and the hypodermis. Finite element results are used to construct the pre-optimisation database which is required for the inverse analysis. To compare the calculations, the entire identification is based on a dual-parameter optimisation procedure: for the single-layer approach a quadratic hyperelastic constitutive equation is used, whereas for the dual-layer medium a simple neo-Hookean potential is used. Theoretical conclusions, which are developed first, are then compared with actual case studies.
authors.affiliation: Centre de Recherche sur la Peau, Pierre Fabre Dermo-Cosmétique, Toulouse, France. alexandre.delalleau@pierre-fabre.com
authors.forename: A
authors.initials: A
authors.lastname: Delalleau
authors.forename: G
authors.initials: G
authors.lastname: Josse
authors.forename: J M
authors.initials: JM
authors.lastname: Lagarde
mesh_terms: D019245:Compressive Strength / Q000502:physiology; D003198:Computer Simulation; D003627:Data Interpretation, Statistical; D055119:Elastic Modulus / Q000502:physiology; D020342:Finite Element Analysis; D006244:Hardness / Q000502:physiology; D006801:Humans; D008422:Materials Testing / Q000379:methods*; D008954:Models, Biological; D015233:Models, Statistical; D012879:Skin Physiological Phenomena; D013269:Stochastic Processes; D013718:Tensile Strength / Q000502:physiology