title: A retrieval analysis of explanted Durom metal-on-metal hip arthroplasties.
abstract: Given the recent reports of high failure rates, an improved understanding of the mechanism of failure of large diameter metal-on-metal hip arthroplasties is essential. We present clinical data and tribological analysis of a consecutive series of 74 failed large diameter metal-on-metal hips, comparing the Durom (Zimmer) with the Birmingham hip resurfacing (BHR) (Smith and Nephew). We retrospectively analysed pre-, intra-, and post-operative clinical data and measured the linear wear and component form of the explanted components using a roundness measuring machine. A significantly higher proportion of hips in the Durom group failed as a result of acetabular loosening (p=0.001) and this was supported by evidence of reduced bone in-growth on the backside of the cup. Comparison of roundness measurement revealed that the Durom hip was significantly lower wearing than the BHR (p<0.05) but the Durom femoral components were subject to significantly greater form errors (p<0.001), the pole of the head being flattened by up to 31 microns. Although the Durom hip is low wearing, reduced sphericity of the femoral component may have resulted in equatorial bearing, leading to an increased frictional torque at the cup-bone interface, preventing bone in-growth, and culminating in acetabular loosening. This supports recent clinical findings of high revision rates as a result of acetabular loosening for the Durom metal-on-metal hip system.
authors.affiliation: Department of Musculoskeletal Surgery, Imperial College London, London, UK. ashley.matthies09@imperial.ac.uk
authors.forename: Ashley K
authors.initials: AK
authors.lastname: Matthies
authors.forename: Johann
authors.initials: J
authors.lastname: Henckel
authors.forename: John A
authors.initials: JA
authors.lastname: Skinner
authors.forename: Alister J
authors.initials: AJ
authors.lastname: Hart
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D019644:Arthroplasty, Replacement, Hip / Q000009:adverse effects*; D001696:Biomechanical Phenomena; D003430:Cross-Sectional Studies; D020878:Device Removal; D019544:Equipment Failure Analysis; D005260:Female; D006622:Hip Prosthesis; D006801:Humans; D008297:Male; D008670:Metals; D008875:Middle Aged; D059035:Perioperative Period; D011474:Prosthesis Design; D011475:Prosthesis Failure; D012189:Retrospective Studies; D055815:Young Adult
chemical_list: D008670:Metals