title: Neurophysiologic intervention in deep brain stimulation treatment for movement disorders: a practical framework.
abstract: Clinical neurophysiology has always played an important interventional role throughout the perioperative stages in functional neurosurgery. On the one hand, some neurophysiologic procedures have become an integrated part of neurosurgery. On the other hand, in deep brain stimulation, although the surgical electrode implantation is an essential step, the therapeutic effects are actually produced by electrically modulating the physiologic activity of the brain. We review the topic of neurophysiologic intervention in the deep brain stimulation for movement disorders by presenting the evidence derived from our own experiences based on an integrated group located at two hospitals in London and Oxford, UK, and mainly covering tremor caused by multiple sclerosis, Parkinson's disease and dystonia.
authors.affiliation: The Movement Disorders and Neurostimulation Group, Department of Neurosciences, Charing Cross Hospital, London, UK;              The Movement Disorders and Pain Group, Department of Neurosurgery, Radcliffe Infirmary, Oxford, UK.
authors.forename: Xuguang
authors.initials: X
authors.lastname: Liu
authors.forename: Peter G
authors.initials: PG
authors.lastname: Bain
authors.forename: Tipu Z
authors.initials: TZ
authors.lastname: Aziz