title: Selective oxoammonium salt oxidations of alcohols to aldehydes and aldehydes to carboxylic acids.
abstract: The oxidation of alcohols to aldehydes using stoichiometric 4-acetamido-2,2,6,6-tetramethylpiperidine-1-oxoammonium tetrafluoroborate (1) in CH(2)Cl(2) at room temperature is a highly selective process favoring reaction at the carbinol center best able to accommodate a positive charge. The oxidation of aldehydes to carboxylic acids by 1 in wet acetonitrile is also selective; the rate of the process correlates with the concentration of aldehyde hydrate. A convenient and high yield method for oxidation of alcohols directly to carboxylic acids has been developed.
authors.affiliation: Department of Chemistry, University of Connecticut, Storrs, Connecticut 06269-3060, USA.
authors.forename: Joseph C
authors.initials: JC
authors.lastname: Qiu
authors.forename: Priya P
authors.initials: PP
authors.lastname: Pradhan
authors.forename: Nyle B
authors.initials: NB
authors.lastname: Blanck
authors.forename: James M
authors.initials: JM
authors.lastname: Bobbitt
authors.forename: William F
authors.initials: WF
authors.lastname: Bailey