title: Huge inflammatory pseudotumor of the spleen with postoperative portal vein thrombosis: report of a case.
abstract: We report the rare case of a splenic inflammatory pseudotumor associated with massive splenomegaly, diagnosed after surgery. A 51-year-old woman was admitted to our hospital for investigation of anemia. Physical examination revealed a palpable left upper quadrant mass. Computed tomography and magnetic resonance imaging showed a splenic mass, 20 cm in diameter. We performed splenectomy for both diagnosis and treatment. The spleen weighed 2400 g, and histologic examination of the mass confirmed an inflammatory pseudotumor. Portal vein thrombosis (PVT) developed the day after surgery, but resolved with anticoagulation therapy. This case highlights that there is a risk of PVT after splenectomy in patients with massive splenomegaly, and that anticoagulant therapy should be initiated promptly.
authors.affiliation: Department of Surgery, Center for Gastroenterology, Clinical Research Institute, National Hospital Organization Kyushu Medical Center, 1-8-1 Jigyohama, Chuo-ku, Fukuoka, 810-8563, Japan. tnori@surg2.med.kyushu-u.ac.jp
authors.forename: Norifumi
authors.initials: N
authors.lastname: Tsutsumi
authors.forename: Hirofumi
authors.initials: H
authors.lastname: Kawanaka
authors.forename: Shohei
authors.initials: S
authors.lastname: Yamaguchi
authors.forename: Masahiro
authors.initials: M
authors.lastname: Sakai
authors.forename: Seiya
authors.initials: S
authors.lastname: Momosaki
authors.forename: Kazuya
authors.initials: K
authors.lastname: Endo
authors.forename: Koji
authors.initials: K
authors.lastname: Ikejiri
mesh_terms: D001799:Blood Sedimentation; D002097:C-Reactive Protein; D005260:Female; D006801:Humans; D007249:Inflammation / Q000097:blood* / Q000473:pathology; D008875:Middle Aged; D011169:Portal Vein / Q000473:pathology*; D013154:Spleen / Q000473:pathology* / Q000601:surgery; D013160:Splenic Neoplasms / Q000150:complications / Q000473:pathology* / Q000601:surgery; D013163:Splenomegaly / Q000150:complications* / Q000473:pathology / Q000601:surgery; D020246:Venous Thrombosis / Q000209:etiology* / Q000473:pathology / Q000601:surgery
chemical_list: D002097:C-Reactive Protein