title: Preparation and optimization of protein-DNA complexes suitable for detailed NMR studies.
abstract: This chapter describes the methods to form and optimize samples of protein-DNA complexes that are suitable for detailed structure and dynamics studies by NMR spectroscopy.
authors.affiliation: Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA.
authors.forename: My D
authors.initials: MD
authors.lastname: Sam
authors.forename: Robert T
authors.initials: RT
authors.lastname: Clubb
mesh_terms: D004247:DNA / Q000737:chemistry* / Q000378:metabolism; D046911:Macromolecular Substances / Q000737:chemistry* / Q000378:metabolism; D019906:Nuclear Magnetic Resonance, Biomolecular / Q000379:methods*; D011485:Protein Binding; D011506:Proteins / Q000737:chemistry* / Q000378:metabolism
chemical_list: D046911:Macromolecular Substances; D011506:Proteins; D004247:DNA