title: Frequency-domain photoacoustic phased array probe for biomedical imaging applications.
abstract: We report the development of a frequency-domain biomedical photoacoustic imaging system that utilizes a continuous-wave laser source with a custom intensity modulation pattern, ultrasonic phased array for signal detection, and processing coupled with a beam-forming algorithm for reconstruction of photoacoustic correlation images. Sensitivity to optical contrast was demonstrated using tissue-mimicking phantoms and in-vivo tissue samples.
authors.affiliation: Center for Advanced Diffusion Wave Technologies, MIE, University of Toronto, 5 King’s College Road, Toronto, Ontario M5S 3G8, Canada. sergeyt@mie.utoronto.ca
authors.forename: Sergey
authors.initials: S
authors.lastname: Telenkov
authors.forename: Rudolf
authors.initials: R
authors.lastname: Alwi
authors.forename: Andreas
authors.initials: A
authors.lastname: Mandelis
authors.forename: Arthur
authors.initials: A
authors.lastname: Worthington
mesh_terms: D000162:Acoustics; D000465:Algorithms; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods* / Q000706:statistics & numerical data; D007834:Lasers; D055620:Optical Phenomena; D019047:Phantoms, Imaging; D061088:Photoacoustic Techniques / Q000295:instrumentation / Q000379:methods* / Q000706:statistics & numerical data; D014463:Ultrasonography / Q000379:methods / Q000706:statistics & numerical data