title: [Endoscopic mucosal resection of sessile polypoid colorectal lesions: a two-year retrospective study, technique description, indications and complications].
abstract: BACKGROUND
  Endoscopic mucosal resection (EMR) is a therapeutic method for removal of sesile premalignant lesions and intramucosal carcinoma of the gastrointestinal tract. No reports on EMR data in Croatia have been published yet.
  
  
  METHODS
  All patients included in the study were managed at the University Hospital Centre Zagreb between December 2006 and December 2008. EMR was performed using strip technique with submucosal injection of epinephrine (dilution with saline 1:5000-10000).
  
  
  RESULTS
  EMR of sessile polypoid colorectal lesions was performed in 95 patients. The most common localisation of the disease was rectum (52 pts - 54.7%). In most patient size of the lesion was between 16-25 mm (43 pts - 45%). En-bloc resection was performed in 75 patients and piecemeal resection in the rest. Bleeding occurred immediately during the EMR in 5 pts (5.3%). Patohistological diagnosis revealed tubulovillous adenoma in 67 pts (70%). Invasive carcinoma was observed in 6 pts (6.3%) and intramucosal carcinoma in 20 pts (21%). On follow up, 73 pts (77%) did not show and sign of disease recurrence. Surgery was needed in 6 pts (6.3%) due to the diagnosis of invasive carcinoma.
  
  
  CONCLUSIONS
  EMR is safe and reliable method with low risk of serious complications and acceptable recurrence rate.
authors.affiliation: Zavod za gastroenterologiju i hepatologiju, Klinika za unutrasnje bolesti Medicinskog fakulteta Sveucilista u Zagrebu, KBC Zagreb.
authors.forename: Pave
authors.initials: P
authors.lastname: Markos
authors.forename: Tomislav
authors.initials: T
authors.lastname: Brkić
authors.forename: Roland
authors.initials: R
authors.lastname: Pulanić
authors.forename: Jasenka
authors.initials: J
authors.lastname: Jakić-Razumović
authors.forename: Hrvoje
authors.initials: H
authors.lastname: Iveković
authors.forename: Marina
authors.initials: M
authors.lastname: Premuzić
authors.forename: Mirjana
authors.initials: M
authors.lastname: Kalauz
authors.forename: Milorad
authors.initials: M
authors.lastname: Opacić
authors.forename: Nadan
authors.initials: N
authors.lastname: Rustemović
authors.forename: Boris
authors.initials: B
authors.lastname: Vucelić
mesh_terms: D000368:Aged; D003111:Colonic Polyps / Q000601:surgery*; D015179:Colorectal Neoplasms / Q000601:surgery*; D016099:Endoscopy, Gastrointestinal; D005260:Female; D006801:Humans; D007413:Intestinal Mucosa / Q000601:surgery*; D008297:Male; D008875:Middle Aged