title: Year in review 2010: Critical Care--Cardiac arrest and cardiopulmonary resuscitation.
abstract: This review will summarize some of the data published in 2010 and focus on papers published in Critical Care in regard to cardiac arrest and cardiopulmonary resuscitation. In particular, we discuss the latest research in therapeutic hypothermia after cardiac arrest, including methods of inducing hypothermia, potential protective mechanisms, spontaneous hypothermia versus therapeutic hypothermia, and several predictors of outcome. Furthermore, we will discuss the effects of bystander-initiated cardiopulmonary resuscitation (CPR) in patients with physician-assisted advanced cardiac life support, the role of hypercapnea in near-death experiences during cardiac arrest, markers of endothelial injury and endothelial repair after CPR, and the prognostic value of cell-free plasma DNA as a marker of poor outcome after cardiac arrest.
authors.affiliation: Department of Surgery, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Mail Code 8579, Dallas, TX 75390-8579, USA. jeffery.metzger@utsouthwestern.edu
authors.forename: Jeffery C
authors.initials: JC
authors.lastname: Metzger
authors.forename: Alexander L
authors.initials: AL
authors.lastname: Eastman
authors.forename: Paul E
authors.initials: PE
authors.lastname: Pepe
mesh_terms: D016887:Cardiopulmonary Resuscitation / Q000379:methods; D003422:Critical Care / Q000379:methods; D006323:Heart Arrest / Q000628:therapy*; D006801:Humans