title: Medication management and neuropsychological performance in Parkinson's disease.
abstract: Medication non-adherence is associated with chronic disease and complex medication schedules, and Parkinson's disease (PD) patients also frequently have cognitive impairments that may interfere with effective medication management. The current study quantitatively assessed the medication management skills of PD patients and probed the neurocognitive underpinnings and clinical correlates of this skill. A total of 26 men with PD completed a neuropsychological battery and a modified version of the Hopkins Medication Schedule (HMS), a standard test of a person's ability to understand and implement a routine prescription medication. Estimated adherence rates from performance on the HMS were low. Memory, executive functioning, and processing speed were strongly related to different components of the HMS. A range of neuropsychological abilities is associated with the ability to understand and implement a medication schedule and pillbox in individuals with PD.
authors.affiliation: Department of Psychology, Drexel University, Philadelphia, PA 19104, USA. kevin.j.manning@gmail.com
authors.forename: Kevin J
authors.initials: KJ
authors.lastname: Manning
authors.forename: Christina
authors.initials: C
authors.lastname: Clarke
authors.forename: Alan
authors.initials: A
authors.lastname: Lorry
authors.forename: Daniel
authors.initials: D
authors.lastname: Weintraub
authors.forename: Jayne R
authors.initials: JR
authors.lastname: Wilkinson
authors.forename: John E
authors.initials: JE
authors.lastname: Duda
authors.forename: Paul J
authors.initials: PJ
authors.lastname: Moberg
mesh_terms: D000203:Activities of Daily Living; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003072:Cognition Disorders / Q000175:diagnosis* / Q000209:etiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D010300:Parkinson Disease / Q000150:complications* / Q000523:psychology / Q000628:therapy*; D010349:Patient Compliance; D011569:Psychiatric Status Rating Scales; D057566:Self Report; D013223:Statistics as Topic