title: Enantioselective carbenoid insertion into phenolic O-H bonds with a chiral copper(I) imidazoindolephosphine complex.
abstract: The enantioselective O-H carbenoid insertion reaction with a new chiral copper(I) imidazoindolephosphine complex has been developed. The chiral copper(I) complex catalyzed the insertion of carbenoids derived from α-diazopropionates into the O-H bonds of various phenol derivatives to give the corresponding α-aryloxypropionates with up to 91% ee.
authors.affiliation: Institute for Molecular Science (IMS), Myodaiji, Okazaki 444-8787, Japan, and RIKEN, Wako 351-0198, Japan.
authors.forename: Takao
authors.initials: T
authors.lastname: Osako
authors.forename: Duanghathai
authors.initials: D
authors.lastname: Panichakul
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Uozumi