title: Should veterinarians consider acrylamide that potentially occurs in starch-rich foodstuffs as a neurotoxin in dogs?
abstract: Three clinically healthy Labrador puppies developed ataxia, hypermetria and convulsions shortly after eating the burnt crust of maize porridge. Two of the puppies died. Acrylamide toxicity was considered based on the history of all 3 puppies developing nervous signs after being exposed to a starch-based foodstuff that was subjected to high temperature during preparation. Acrylamide-induced neurotoxicity is thought to partially result from a distal axonopathy.
authors.affiliation: Department of Paraclinical Sciences, Faculty of Veterinary Science, University of Pretoria, Private Bag X04, Onderstepoort 0110, South Africa. lerica.leroux@up.ac.za
authors.forename: L
authors.initials: L
authors.lastname: Le Roux-Pullen
authors.forename: D
authors.initials: D
authors.lastname: Lessing
mesh_terms: D020106:Acrylamide / Q000032:analysis / Q000506:poisoning*; D000818:Animals; D000831:Animals, Newborn; D004283:Dog Diseases / Q000139:chemically induced*; D004285:Dogs; D017809:Fatal Outcome; D005506:Food Contamination / Q000032:analysis*
chemical_list: D020106:Acrylamide