title: Isolation of C₁₁ compounds and a cyclopropane fatty acid from an Okinawan ascidian, Diplosoma sp.
abstract: Pentylphenols 1 and 2, cyclopropane fatty acid 3, and cyclopentenones 4 and 5, were isolated from an ascidian, Diplosoma sp. The structures of 1-5 were determined by spectroscopic analysis and/or synthesis. Compound 1 inhibited the division of fertilized sea urchin eggs and compound 4 showed mild cytotoxity against HCT116 cells (human colorectal cancer cell).
authors.affiliation: Department of Chemistry, Biology and Marine Science, University of the Ryukyus, Nishihara-cho Okinawa 903-0123, Japan.
authors.forename: Tamanna
authors.initials: T
authors.lastname: Rob
authors.forename: Takayuki
authors.initials: T
authors.lastname: Ogi
authors.forename: Wilmar
authors.initials: W
authors.lastname: Maarisit
authors.forename: Junsei
authors.initials: J
authors.lastname: Taira
authors.forename: Katsuhiro
authors.initials: K
authors.lastname: Ueda
mesh_terms: D000818:Animals; D003521:Cyclopropanes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D005227:Fatty Acids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D045325:HCT116 Cells; D006801:Humans; D007564:Japan; D009682:Magnetic Resonance Spectroscopy; D009930:Organic Chemicals / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D012617:Sea Urchins / Q000166:cytology / Q000187:drug effects; D014561:Urochordata / Q000737:chemistry*
chemical_list: D003521:Cyclopropanes; D005227:Fatty Acids; D009930:Organic Chemicals; C028775:cyclopropane fatty acids