title: [Reaction of gingival mucosa on the biodegradated film under chronic periodontitis treatment: morpho-functional correlation].
abstract: Purpose - to study the morphological justification of biopolymer film on the gingival mucosa in chronic periodontitis.  The samples of gingival mucosa from 42 patients with moderate degree of chronic periodontitis in the acute stage were researched. We determined the specific stomatologic indices of oral cavity and periodontal pocket depth. Treatment started with application to the gingiva biopolymer film with different ingredients (antibiotics etc.). Morphology and ultrastructure of epithelial component was investigated after 24 hours, 7 days and 3 months. Clinical indicators were estimated in the dynamics (24, 48 hours, 7-10 days, 3 months). Based on histo-ultrastructural data of strutified squamous epithelium and stomatologic indices of the oral cavity, we can conclude that the use of biodegradable polymer film leads to the regression of the process, reducing periodontal pocket depth, repair germinal and upper layers of epithelium, and in general, activates the reparative and regenerative processes in the gingival mucosa.
authors.forename: K
authors.initials: K
authors.lastname: Kandelaki
authors.forename: N
authors.initials: N
authors.lastname: Alavidze
authors.forename: I
authors.initials: I
authors.lastname: Pkhakadze
authors.forename: M
authors.initials: M
authors.lastname: Dgebuadze
authors.forename: E
authors.initials: E
authors.lastname: Melikadze
mesh_terms: D000328:Adult; D001704:Biopolymers / Q000627:therapeutic use*; D055113:Chronic Periodontitis / Q000473:pathology* / Q000628:therapy*; D004848:Epithelium / Q000473:pathology / Q000648:ultrastructure; D005260:Female; D005881:Gingiva / Q000473:pathology / Q000648:ultrastructure; D006801:Humans; D008297:Male; D008854:Microscopy, Electron / Q000379:methods; D008875:Middle Aged; D009061:Mouth Mucosa / Q000473:pathology / Q000648:ultrastructure; D010514:Periodontal Pocket / Q000473:pathology / Q000628:therapy*
chemical_list: D001704:Biopolymers