title: An improved border detection in dermoscopy images for density based clustering.
abstract: BACKGROUND
  Dermoscopy is one of the major imaging modalities used in the diagnosis of melanoma and other pigmented skin lesions. In current practice, dermatologists determine lesion area by manually drawing lesion borders. Therefore, automated assessment tools for dermoscopy images have become an important research field mainly because of inter- and intra-observer variations in human interpretation. One of the most important steps in dermoscopy image analysis is automated detection of lesion borders. To our knowledge, in our 2010 study we achieved one of the highest accuracy rates in the automated lesion border detection field by using modified density based clustering algorithm. In the previous study, we proposed a novel method which removes redundant computations in well-known spatial density based clustering algorithm, DBSCAN; thus, in turn it speeds up clustering process considerably.
  
  
  RESULTS
  Our previous study was heavily dependent on the pre-processing step which creates a binary image from original image. In this study, we embed a new distance measure to the existing algorithm. This provides twofold benefits. First, since new approach removes pre-processing step, it directly works on color images instead of binary ones. Thus, very important color information is not lost. Second, accuracy of delineated lesion borders is improved on 75% of 100 dermoscopy image dataset.
  
  
  CONCLUSIONS
  Previous and improved methods are tested within the same dermoscopy dataset along with the same set of dermatologist drawn ground truth images. Results revealed that the improved method directly works on color images without any pre-processing and generates more accurate results than existing method.
authors.affiliation: University of Central Arkansas, 201 Donaghey Ave, Conway, 72035 AR, USA.
authors.forename: Sait
authors.initials: S
authors.lastname: Suer
authors.forename: Sinan
authors.initials: S
authors.lastname: Kockara
authors.forename: Mutlu
authors.initials: M
authors.lastname: Mete
mesh_terms: D000465:Algorithms; D016000:Cluster Analysis; D046169:Dermoscopy / Q000379:methods*; D006801:Humans; D007090:Image Interpretation, Computer-Assisted / Q000379:methods; D008545:Melanoma / Q000175:diagnosis* / Q000473:pathology; D015588:Observer Variation; D010363:Pattern Recognition, Automated / Q000379:methods; D012878:Skin Neoplasms / Q000175:diagnosis* / Q000473:pathology