title: Pd-catalyzed oxidative ortho-C-H borylation of arenes.
abstract: The development of a Pd-catalyzed oxidative ortho-C-H borylation with N-arylbenzamides is reported. A modified dibenzylideneacetone (dba) ligand, a weak base, and a strong oxidant are critical for obtaining good yields. The reaction is tolerant of electron-deficient and electron-rich benzamides derived from readily available benzoic acids. The borylated products can be converted to various synthons via diverse transformations.
authors.affiliation: Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA.
authors.forename: Hui-Xiong
authors.initials: HX
authors.lastname: Dai
authors.forename: Jin-Quan
authors.initials: JQ
authors.lastname: Yu
mesh_terms: D001554:Benzene / Q000737:chemistry*; D001895:Boron / Q000737:chemistry*; D002244:Carbon / Q000737:chemistry*; D002384:Catalysis; D006859:Hydrogen / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*
chemical_list: D010165:Palladium; D002244:Carbon; D006859:Hydrogen; D001554:Benzene; D001895:Boron