title: Operating principles and clinical implications of constant flow pumps.
abstract: Intrathecal drug therapy has become an indispensable tool in the treatment of many different neurologic disorders. It allows targeted infusion of small quantities of drugs, thereby increasing effectiveness while reducing unwanted side effects typically seen in oral drug administration. The following paper discusses the current technology in constant rate intrathecal drug-infusion delivery systems and the effect of pressure and temperature on flow rate accuracy.
authors.affiliation: Department of Bioengineering, University of Texas Southwestern Medical School, Dallas, Texas;              Department of Surgery, University of Minnesota, Minneapolis, Minnesota;              Health South Alaska Surgery Center, Anchorage, Alaska.
authors.forename: Tracy
authors.initials: T
authors.lastname: Cameron
authors.forename: Bruce D
authors.initials: BD
authors.lastname: Wigness
authors.forename: Marshall D
authors.initials: MD
authors.lastname: Bedder