title: When two metal centres are needed instead of one: exclusive induction of Z-DNA by dinuclear metal complexes.
abstract: The B- to Z-DNA transition was very efficiently induced by dinuclear nickel and copper complexes based on the 1,3-bis(1,5,9-triazacyclododecyl) propane ligand but not by the corresponding mononuclear complexes. This dramatically different behaviour is explained by the formation of a macrochelate of the dinuclear complexes to the DNA.
authors.affiliation: Institute of Inorganic Chemistry, University of Zurich, Winterthurerstr. 190, CH 8057 Zurich, Switzerland.
authors.forename: Alfredo
authors.initials: A
authors.lastname: Medina-Molner
authors.forename: Bernhard
authors.initials: B
authors.lastname: Spingler
mesh_terms: D056831:Coordination Complexes / Q000737:chemistry*; D003300:Copper / Q000737:chemistry*; D018360:Crystallography, X-Ray; D043542:DNA, Z-Form / Q000737:chemistry*; D008024:Ligands; D008968:Molecular Conformation; D009532:Nickel / Q000737:chemistry*
chemical_list: D056831:Coordination Complexes; D043542:DNA, Z-Form; D008024:Ligands; D003300:Copper; D009532:Nickel