title: High specific activity tritiation of the pyridazin-3-one histamine H3 receptor inverse agonist CEP-27088.
abstract: Methods are presented to tritiate and characterize radioligand (3).
authors.affiliation: PerkinElmer Health Sciences, Inc., Waltham, MA 02451, USA.
authors.forename: Joseph R
authors.initials: JR
authors.lastname: Andrews
authors.forename: Crist N
authors.initials: CN
authors.lastname: Filer
authors.forename: Mario
authors.initials: M
authors.lastname: Maniscalco
authors.forename: Nadine C
authors.initials: NC
authors.lastname: Becknell
authors.forename: Robert L
authors.initials: RL
authors.lastname: Hudkins
mesh_terms: D017442:Histamine Agonists / Q000494:pharmacology*; D009682:Magnetic Resonance Spectroscopy; D011724:Pyridazines / Q000494:pharmacology*; D011759:Pyrrolidines / Q000494:pharmacology*; D018100:Receptors, Histamine H3 / Q000187:drug effects*; D021241:Spectrometry, Mass, Electrospray Ionization
chemical_list: C571879:CEP-27088; D017442:Histamine Agonists; D011724:Pyridazines; D011759:Pyrrolidines; D018100:Receptors, Histamine H3