title: Enantioselective total synthesis of (+)-galbulin via organocatalytic domino Michael-Michael-aldol condensation.
abstract: A concise and practical enantioselective synthesis of (+)-galbulin has been achieved using organocatalytic domino Michael-Michael-aldol condensation and organocatalytic kinetic resolution as the key steps.
authors.affiliation: Department of Chemistry and Biochemistry, National Chung Cheng University, Chia-Yi 621, Taiwan, ROC. chebch@ccu.edu.tw
authors.forename: Bor-Cherng
authors.initials: BC
authors.lastname: Hong
authors.forename: Che-Sheng
authors.initials: CS
authors.lastname: Hsu
authors.forename: Gene-Hsiang
authors.initials: GH
authors.lastname: Lee
mesh_terms: D000447:Aldehydes / Q000737:chemistry*; D002384:Catalysis; D060326:Chemistry Techniques, Synthetic / Q000379:methods*; D007659:Ketones / Q000737:chemistry*; D008958:Models, Molecular; D008968:Molecular Conformation; D013237:Stereoisomerism; D013379:Substrate Specificity; D013764:Tetrahydronaphthalenes / Q000138:chemical synthesis* / Q000737:chemistry*
chemical_list: D000447:Aldehydes; D007659:Ketones; D013764:Tetrahydronaphthalenes; C412027:galbulin