title: Detection and molecular characterization of cosavirus in adults with diarrhea, Thailand.
abstract: Human cosavirus (HCoSV) is a newly discovered virus in Picornaviridae family. At present it is not clear whether HCoSV is associated with diseases, including gastroenteritis in humans, as epidemiological data is limited. Epidemiological surveillance of HCoSV was conducted on 150 fecal specimens collected from children and 150 samples from adults with diarrhea in Thailand by RT-PCR screening. HCoSV was found in a single adult specimen and not in any of the fecal specimens from children. This represents the first report of HCoSV infection in patients with diarrhea in Thailand. Extensive epidemiological surveillance of novel viruses associated with diarrhea in other populations may provide a better understanding of the distribution, genetic diversity, and association of the viral agents associated with acute gastroenteritis in humans.
authors.affiliation: Department of Microbiology, Faculty of Medicine, Chiang Mai University, 110 Intawarorose, Sriphoom, Muang, Chiang Mai 50200, Thailand.
authors.forename: Pattara
authors.initials: P
authors.lastname: Khamrin
authors.forename: Natthawan
authors.initials: N
authors.lastname: Chaimongkol
authors.forename: Rungnapa
authors.initials: R
authors.lastname: Malasao
authors.forename: Boonpa
authors.initials: B
authors.lastname: Suantai
authors.forename: Wilaiporn
authors.initials: W
authors.lastname: Saikhruang
authors.forename: Tipachan
authors.initials: T
authors.lastname: Kongsricharoern
authors.forename: Nuthapong
authors.initials: N
authors.lastname: Ukarapol
authors.forename: Shoko
authors.initials: S
authors.lastname: Okitsu
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Shimizu
authors.forename: Satoshi
authors.initials: S
authors.lastname: Hayakawa
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Ushijima
authors.forename: Niwat
authors.initials: N
authors.lastname: Maneekarn
mesh_terms: D000328:Adult; D002648:Child; D002675:Child, Preschool; D003967:Diarrhea / Q000453:epidemiology* / Q000821:virology*; D005243:Feces / Q000821:virology; D006801:Humans; D008403:Mass Screening / Q000379:methods; D008969:Molecular Sequence Data; D010849:Picornaviridae / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification*; D010850:Picornaviridae Infections / Q000453:epidemiology* / Q000821:virology*; D012367:RNA, Viral / Q000235:genetics; D020133:Reverse Transcriptase Polymerase Chain Reaction / Q000379:methods; D017422:Sequence Analysis, DNA; D013785:Thailand / Q000453:epidemiology
chemical_list: D012367:RNA, Viral