title: Sexual dysfunction in women with ketamine cystitis: a case-control study.
abstract: OBJECTIVE
  • To conduct a case-control study evaluating clinical symptom severity and sexual dysfunction in women with ketamine cystitis (KC).
  
  
  METHODS
  • In total, 29 patients with KC and 27 controls completed the symptoms survey. • Participants completed a visual pelvic pain analogue scale, an O'Leary-Sant Interstitial Cystitis Symptom Index and Problem Index questionnaire, a Female Sexual Function Index, and a short form of the Chinese Health Questionnaire-12.
  
  
  RESULTS
  • Both the Interstitial Cystitis Symptom Index and Interstitial Cystitis Problem Index scores were significantly higher in patients with KC compared to controls (P < 0.001). • The prevalence of sexual dysfunction was high in patients with KC. • There was a difference in total adjusted Female Sexual Function Index scores between the patients with KC and controls: mean (sd) total Female Sexual Function Index score 17.65 (6.15) for KC cases vs 25.87 (4.16) for controls (P < 0.001). • Except for the sexual desire domain of female sexual dysfunction, patients with KC scored lower on all domains compared to controls. • There was no significant difference between patients with KC and controls with respect to mental health as evaluated by the Chinese Health Questionnaire-12.
  
  
  CONCLUSIONS
  • Sexual dysfunction and KC symptoms severely impacted on quality of life. • Mental health had no significant difference between patients with KC and controls.
authors.affiliation: Department of Urology, Kaohsiung Municipal Hsia-Kang Hospital, Kaohsiung, Taiwan.
authors.forename: Mei-Yu
authors.initials: MY
authors.lastname: Jang
authors.forename: Cheng-Yu
authors.initials: CY
authors.lastname: Long
authors.forename: Shu-Mien
authors.initials: SM
authors.lastname: Chuang
authors.forename: Chun-Hsiung
authors.initials: CH
authors.lastname: Huang
authors.forename: Hung-Yu
authors.initials: HY
authors.lastname: Lin
authors.forename: Wen-Jen
authors.initials: WJ
authors.lastname: Wu
authors.forename: Yung-Shun
authors.initials: YS
authors.lastname: Juan
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D003430:Cross-Sectional Studies; D018856:Cystitis, Interstitial / Q000139:chemically induced*; D018691:Excitatory Amino Acid Antagonists / Q000633:toxicity*; D005260:Female; D006801:Humans; D007649:Ketamine / Q000633:toxicity*; D012735:Sexual Dysfunction, Physiological / Q000139:chemically induced*; D019966:Substance-Related Disorders / Q000150:complications*; D055815:Young Adult
chemical_list: D018691:Excitatory Amino Acid Antagonists; D007649:Ketamine