title: Transcription and mRNA stability: parental guidance suggested.
abstract: The level of an mRNA within a cell depends on both its rate of synthesis and rate of decay. Now, independent studies by Bregman et al. and Trcek et al. provide evidence that these two processes are integrated. They show that transcription factors and DNA promoters can directly influence the relative stability of transcripts that they produce.
authors.affiliation: Department of Microbiology and Molecular Genetics, UMDNJ-New Jersey Medical School, Newark, NJ 07103, USA. bellofat@umdnj.edu
authors.forename: Vivian
authors.initials: V
authors.lastname: Bellofatto
authors.forename: Jeffrey
authors.initials: J
authors.lastname: Wilusz