title: Aqueous synthesis of silver nanoparticle embedded cationic polymer nanofibers and their antibacterial activity.
abstract: This paper describes the one-pot, aqueous synthesis of cationic polymer nanofibers with embedded silver nanoparticles. Poly[2-(tert-butylaminoethyl) methacrylate] (PTBAM) was used as a cationic polymer substrate to reinforce the antimicrobial activity of the embedded silver nanoparticles. Electron microscope analyses revealed that the as-synthesized nanofibers had diameters of approximately 40 nm and lengths up to about 10 μm. Additionally, silver nanoparticles of approximately 8 nm in diameter were finely embedded into the prepared nanofibers. The embedded silver nanoparticles had a lower tendency to agglomerate than colloidal silver nanoparticles of comparable size. In addition, the nanofibers with embedded silver nanoparticles exhibited excellent antibacterial performance against Gram-negative Escherichia coli and Gram-positive Staphylococcus aureus. Interestingly, the prepared nanofibers exhibited enhanced bactericidal performance compared with the silver-embedded poly(methyl methacrylate) (PMMA) nanofibers, presumably because of the antibacterial properties of the PTBAM substrate.
authors.affiliation: WCU program of Chemical Convergence for Energy and Environment (C2E2), School of Chemical and Biological Engineering, College of Engineering, Seoul National University, 599 Gwanak-ro, Gwanak-gu, Seoul 151-742, Korea.
authors.forename: Jooyoung
authors.initials: J
authors.lastname: Song
authors.forename: Haeyoung
authors.initials: H
authors.lastname: Kang
authors.forename: Choonghyeon
authors.initials: C
authors.lastname: Lee
authors.forename: Sun Hye
authors.initials: SH
authors.lastname: Hwang
authors.forename: Jyongsik
authors.initials: J
authors.lastname: Jang
mesh_terms: D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D004926:Escherichia coli / Q000187:drug effects; D053768:Metal Nanoparticles / Q000737:chemistry* / Q000633:toxicity; D057139:Nanofibers / Q000737:chemistry*; D011108:Polymers / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D012834:Silver / Q000737:chemistry* / Q000494:pharmacology; D013211:Staphylococcus aureus / Q000187:drug effects
chemical_list: D000900:Anti-Bacterial Agents; D011108:Polymers; D012834:Silver