title: [Diagnostic aspects of chronic cholangitis after cholecystectomy].
abstract: OBJECTIVE
  To determine the chronic cholangitis risk factors and to provide a practically significant diagnostic criteria of chronic cholangitis in patients after cholecystectomy.
  
  
  METHODS
  Were examined the clinical, anamnestic data, clinical laboratory and instrumental studies of the condition of the hepatobiliary system in 127 patients with chronic cholangitis after cholecystectomy. The determination of microbial contamination of bile was performed during the duodenal intubation.
  
  
  RESULTS
  In the bile microbial landscape study were noted the violation of biliary system microbiota in 92.1% of cases. Herewith identified a combination of bacterial factors with parasitic invasion (mixed infection) in 28 (22.0%) patients. Cholangitis develops in the presence of duodeno biliary reflux, duodenal motility disorders and hypotonia of Oddi's sphincter in the early postoperative period. In the late periods after cholecystectomy, cholangitis chronization defines outflow obstruction and cholestasis due to functional or organic causes in most patients.
  
  
  CONCLUSIONS
  Risk factors for chronic cholangitis should be referred to long history of gallstone disease, performance of cholecystectomy in the emergency order against the inflammatory process of thehepatobiliary system, absence of adequate correction of postoperative hypertension of bile duct, destruction of sphincter apparatus major duodenal papilla during surgery.
authors.forename: I O
authors.initials: IO
authors.lastname: Gibadulina
authors.forename: N V
authors.initials: NV
authors.lastname: Gibadulin
mesh_terms: D000328:Adult; D000368:Aged; D001659:Biliary Tract / Q000382:microbiology / Q000473:pathology / Q000503:physiopathology; D002761:Cholangitis / Q000175:diagnosis* / Q000209:etiology / Q000382:microbiology / Q000473:pathology / Q000503:physiopathology; D002763:Cholecystectomy / Q000009:adverse effects*; D002908:Chronic Disease; D004383:Duodenogastric Reflux / Q000175:diagnosis / Q000209:etiology / Q000382:microbiology / Q000473:pathology / Q000503:physiopathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000175:diagnosis* / Q000382:microbiology / Q000473:pathology / Q000503:physiopathology; D012307:Risk Factors; D013997:Time Factors