title: [Postpartum haemorrhage and factor VII deficiency].
abstract: During pregnancy, the plasma concentration of factor VII increases to reach values during the third trimester that can be twice the normal values (N: 70% to 140%). Congenital factor VII deficiency is a rare condition which may lead to haemorrhage. We report the case of a patient with a congenital factor VII deficiency who presented with severe postpartum haemorrhage requiring resuscitation with blood transfusion and surgical haemostasis. We discuss the treatment of congenital factor VII deficiency and its anaesthetic management, as well as the hemorrhagic risk during pregnancy.
authors.affiliation: Service d'anesthésie-réanimation, hôpital Bicêtre, AP-HP, 94275 Le Kremlin-Bicêtre cedex, France.
authors.forename: H
authors.initials: H
authors.lastname: Harkouk
authors.forename: F
authors.initials: F
authors.lastname: Chakib Rahmoune
authors.forename: D
authors.initials: D
authors.lastname: Benhamou
mesh_terms: D000328:Adult; D005168:Factor VII Deficiency / Q000150:complications*; D005260:Female; D006801:Humans; D006473:Postpartum Hemorrhage / Q000209:etiology*