title: Gemella morbillorum bacteremia after anti-tumor necrosis factor alpha as acne inversa therapy.
abstract: We present a case of fever, brain abscesses, and Gemella morbillorum bacteremia after anti-tumor necrosis factor alpha (TNF-α) therapy in a 21-year-old acne inversa patient currently taking long-term dapsone. To the best of our knowledge, this is the first report describing such a case. During antimicrobial therapy, the patient developed systemic varicella infection with severe thrombocytopenia.
authors.affiliation: Department of Medicine I, Division of Infectious Diseases and Tropical Medicine, Medical University of Vienna, Vienna, Austria. heimo.lagler@meduniwien.ac.at
authors.forename: Matthias G
authors.initials: MG
authors.lastname: Vossen
authors.forename: Klaus B
authors.initials: KB
authors.lastname: Gattringer
authors.forename: Neda
authors.initials: N
authors.lastname: Khalifeh
authors.forename: Maria
authors.initials: M
authors.lastname: Koreny
authors.forename: Verena
authors.initials: V
authors.lastname: Spertini
authors.forename: Ammar
authors.initials: A
authors.lastname: Mallouhi
authors.forename: Markus
authors.initials: M
authors.lastname: Willeit
authors.forename: Beatrix
authors.initials: B
authors.lastname: Volc-Platzer
authors.forename: Friederike
authors.initials: F
authors.lastname: Asboth
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Graninger
authors.forename: Florian
authors.initials: F
authors.lastname: Thalhammer
authors.forename: Heimo
authors.initials: H
authors.lastname: Lagler
mesh_terms: D000890:Anti-Infective Agents / Q000008:administration & dosage; D000906:Antibodies / Q000008:administration & dosage / Q000009:adverse effects*; D016470:Bacteremia / Q000150:complications / Q000175:diagnosis* / Q000382:microbiology; D001922:Brain Abscess / Q000175:diagnosis / Q000382:microbiology; D003622:Dapsone / Q000008:administration & dosage; D058834:Gemella / Q000302:isolation & purification*; D016908:Gram-Positive Bacterial Infections / Q000175:diagnosis* / Q000382:microbiology; D017497:Hidradenitis Suppurativa / Q000150:complications / Q000188:drug therapy*; D006801:Humans; D007155:Immunologic Factors / Q000008:administration & dosage / Q000009:adverse effects*; D008297:Male; D014409:Tumor Necrosis Factor-alpha / Q000037:antagonists & inhibitors*; D055815:Young Adult
chemical_list: D000890:Anti-Infective Agents; D000906:Antibodies; D007155:Immunologic Factors; D014409:Tumor Necrosis Factor-alpha; D003622:Dapsone