title: [Molecular and epidemiology studies of HIV-1 prevalence in the Republic of Sakha (Yakutia)].
abstract: The gag, pol, and env genomic regions of HIV-1 variants currently circulating in the Republic of Sakha (Yakutia) were analyzed. The results of the study indicated that in this area there were HIV-1 variants belonging to two subtypes: A (IDU-A) and B, the former being predominant in this area and in the Russian Federation. The IDU-B-East strain was first isolated from a heterosexually infected patient, which suggests that the strain is outside the risk group of injection drug users. No cases of primary infection with resistant variants were notified during the study.
authors.forename: E V
authors.initials: EV
authors.lastname: Kazennova
authors.forename: O V
authors.initials: OV
authors.lastname: Antonova
authors.forename: S N
authors.initials: SN
authors.lastname: Kuzin
authors.forename: T P
authors.initials: TP
authors.lastname: Serkina
authors.forename: L S
authors.initials: LS
authors.lastname: Sokolova
authors.forename: A V
authors.initials: AV
authors.lastname: Vasil'ev
authors.forename: I A
authors.initials: IA
authors.lastname: Lapovok
authors.forename: M R
authors.initials: MR
authors.lastname: Bobkova
mesh_terms: D000328:Adult; D000595:Amino Acid Sequence / Q000235:genetics; D019380:Anti-HIV Agents / Q000494:pharmacology / Q000627:therapeutic use; D004196:Disease Outbreaks; D024882:Drug Resistance, Viral / Q000235:genetics; D005260:Female; D015752:Genes, env / Q000235:genetics*; D015750:Genes, gag / Q000235:genetics*; D015751:Genes, pol / Q000235:genetics*; D015658:HIV Infections / Q000453:epidemiology / Q000235:genetics; D015497:HIV-1 / Q000145:classification / Q000235:genetics*; D006801:Humans; D008297:Male; D008875:Middle Aged; D017720:Molecular Epidemiology; D010802:Phylogeny; D015995:Prevalence; D012800:Siberia / Q000453:epidemiology; D013386:Succinates / Q000494:pharmacology / Q000627:therapeutic use; D014315:Triterpenes / Q000494:pharmacology / Q000627:therapeutic use; D053978:Pentacyclic Triterpenes
chemical_list: D019380:Anti-HIV Agents; D013386:Succinates; D014315:Triterpenes; C479935:bevirimat; D053978:Pentacyclic Triterpenes