title: Model system of self-reproducing vesicles.
abstract: Development of self-reproducing vesicle systems is the first step for autopoietic cycles. We established a model self-reproducing vesicle system without the membrane molecule synthesis route. The model vesicle composed of cylinder- and inverse-cone-shaped lipids formed inclusion vesicles inside the mother vesicle, and the inclusion vesicles were then expelled by a temperature cycling. By changing the vesicle composition, the mother vesicles showed a budding-type self-reproduction pathway. A key concept of this system is the coupling of the main-chain transition and the shape of lipids.
authors.affiliation: Department of Physics, Ochanomizu University, Bunkyo, Tokyo 112-8610, Japan.
authors.forename: Yuka
authors.initials: Y
authors.lastname: Sakuma
authors.forename: Masayuki
authors.initials: M
authors.lastname: Imai
mesh_terms: D008051:Lipid Bilayers / Q000737:chemistry*; D008055:Lipids / Q000737:chemistry*; D008081:Liposomes / Q000737:chemistry*; D008954:Models, Biological; D008962:Models, Theoretical
chemical_list: D008051:Lipid Bilayers; D008055:Lipids; D008081:Liposomes