title: Host defence against Candida albicans and the role of pattern-recognition receptors.
abstract: Recognition of Candida albicans is mediated by several classes of pattern-recognition receptors, including Toll-like receptors and C-type lectin receptors. Cell wall components of C. albicans, interact with the pattern-recognition receptors, which are expressed by different cells, primarily antigen-presenting cells. This review aims to discuss the different pattern-recognition receptors responsible for recognition of special structures of C. albicans, which are known to activate intracellular signals that finally lead to directed and efficient host defence.
authors.affiliation: Department of Dermatology and Allergology, Ludwig-Maximilian-University, D-80337 Munich, Germany. Gerd.Gauglitz@med.uni-muenchen.de
authors.forename: Gerd G
authors.initials: GG
authors.lastname: Gauglitz
authors.forename: Helene
authors.initials: H
authors.lastname: Callenberg
authors.forename: Günther
authors.initials: G
authors.lastname: Weindl
authors.forename: Hans C
authors.initials: HC
authors.lastname: Korting
mesh_terms: D002176:Candida albicans / Q000276:immunology*; D002177:Candidiasis / Q000276:immunology*; D037222:Collectins / Q000276:immunology; D006801:Humans; D007113:Immunity, Innate; D037181:Lectins, C-Type / Q000276:immunology*; D011951:Receptors, Complement / Q000276:immunology; D051192:Receptors, Pattern Recognition / Q000276:immunology*; D015398:Signal Transduction; D051193:Toll-Like Receptors / Q000276:immunology*
chemical_list: D037222:Collectins; D037181:Lectins, C-Type; D011951:Receptors, Complement; D051192:Receptors, Pattern Recognition; D051193:Toll-Like Receptors