title: Acute corneal melt associated with topical bromfenac use.
abstract: OBJECTIVE
  To report a case of acute corneal melt associated with use of bromfenac ophthalmic solution.
  
  
  METHODS
  Case report.
  
  
  RESULTS
  A 61-year-old man developed acute corneal melt 5 days after having combined cataract and pterygium surgery in his left eye. Postoperatively, he had been using bromfenac eyedrops four times daily along with the combination of ofloxacin and dexamethasone six times and timolol eyedrops twice daily. Ocular examination revealed the presence of asymptomatic dry eyes. He was managed conservatively with topical antibiotics, lubricants, and bandage contact lens application. The corneal melt healed completely with best-corrected visual acuity of 20/30 at 4 weeks postoperatively.
  
  
  CONCLUSIONS
  The current case suggests that corneal melt can occur as a complication of inadvertent excessive use of topical bromfenac in the presence of preexisting ocular surface disorders. However, good visual outcome can be achieved by prompt conservative treatment if accurate diagnosis is made at an early stage.
authors.affiliation: Department of Ophthalmology, Sri Guru Ram Das Institute of Medical Sciences and Research, Vallah, Amritsar, Punjab, India. pawanprasher@yahoo.com
authors.forename: Pawan
authors.initials: P
authors.lastname: Prasher
mesh_terms: D000208:Acute Disease; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000009:adverse effects*; D001577:Benzophenones / Q000008:administration & dosage / Q000009:adverse effects*; D001969:Bromobenzenes / Q000008:administration & dosage / Q000009:adverse effects*; D057112:Corneal Perforation / Q000139:chemically induced*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009883:Ophthalmic Solutions / Q000009:adverse effects*
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D001577:Benzophenones; D001969:Bromobenzenes; D009883:Ophthalmic Solutions; C053083:bromfenac