title: [Osteosynthesis with 2-octylcyanoacrylate and sodium bicarbonate in zygomatic arch fractures: animal model results].
abstract: BACKGROUND
  2-octylcyanoacrylate (2OCA) is a liquid monomer that polymerizes on contact with a surface by an exothermic reaction creating a strong and flexible film. The addition of sodium bicarbonate accelerates the polymerization. The aim was to use the combination of 2OCA and sodium bicarbonate in the treatment of zygomatic arch fractures in an animal model and to evaluate the biocompatibility and bone healing.
  
  
  METHODS
  twenty animals were subjected to bilateral zygomatic arch fracture under surgical sedation, and using 2OCA fixation and sodium bicarbonate for the experimental side and without fixation for the control side. Observation was over a period from two to four weeks, assessing biocompatibility, stability and consolidation.
  
  
  RESULTS
  at the end of two and four weeks the twenty animals showed the presence of osseous callus and continuity of marrow channel measured by macroscopic and radiography examinations.
  
  
  CONCLUSIONS
  the use of 2-octylcyanoacrylate and sodium bicarbonate led to the stabilization and reduction of bilateral zygomatic arch fractures in an animal model without adverse reactions.
authors.affiliation: Instituto Mexicano del Seguro Social, Distrito Federal, México. tamayogm07@hotmail.com
authors.forename: Mariana
authors.initials: M
authors.lastname: García-Tamayo
authors.forename: José Guadalupe
authors.initials: JG
authors.lastname: González-Martínez
authors.forename: Marco Antonio
authors.initials: MA
authors.lastname: García-Huerta
authors.forename: Mario
authors.initials: M
authors.lastname: Campos-Jiménez
authors.forename: María Luisa
authors.initials: ML
authors.lastname: Márquez-Rocha
mesh_terms: D000818:Animals; D003487:Cyanoacrylates; D005592:Fracture Fixation / Q000379:methods*; D017693:Sodium Bicarbonate; D014014:Tissue Adhesives; D015051:Zygomatic Fractures / Q000188:drug therapy*
chemical_list: D003487:Cyanoacrylates; D014014:Tissue Adhesives; C100832:octyl 2-cyanoacrylate; D017693:Sodium Bicarbonate