title: Metabolic connections during apoptotic cell engulfment.
abstract: Billions of cells die via apoptosis every day and are swiftly removed. When a phagocyte engulfs an apoptotic cell, it essentially doubles its cellular contents, raising the question of how a phagocyte may manage the excess metabolic load. This Minireview discusses phagocyte cellular metabolism, the digestion of the ingested apoptotic cell, and the impact of these processes on engulfment.
authors.affiliation: Department of Microbiology, Immunology, and Cancer Biology, Carter Immunology Center and the Center for Cell Clearance, University of Virginia, Charlottesville, VA 22908, USA.
authors.forename: Claudia Z
authors.initials: CZ
authors.lastname: Han
authors.forename: Kodi S
authors.initials: KS
authors.lastname: Ravichandran
mesh_terms: D000818:Animals; D017209:Apoptosis; D002468:Cell Physiological Phenomena; D005947:Glucose / Q000378:metabolism; D006801:Humans; D050356:Lipid Metabolism; D010586:Phagocytes / Q000378:metabolism*; D010587:Phagocytosis
chemical_list: D005947:Glucose