title: Olanzapine-associated myoclonus.
abstract: Olanzapine is an atypical antipsychotic drug that infrequently has been reported to cause seizures and myoclonus despite a small proconvulsant risk. This is the first report of generalized myoclonus induced in a patient who had been maintained on low dose olanzapine for over seven years without any change in her dose. Olanzapine was discontinued, and the myoclonic jerks completely resolved within 48 h.
authors.affiliation: Montefiore Medical Center, 111 East 210th Street, Bronx, NY 10467, USA.
authors.forename: Jennifer Block
authors.initials: JB
authors.lastname: Rosen
authors.forename: Mark J
authors.initials: MJ
authors.lastname: Milstein
authors.forename: Sheryl R
authors.initials: SR
authors.lastname: Haut
mesh_terms: D000368:Aged; D000544:Alzheimer Disease / Q000150:complications / Q000188:drug therapy; D014150:Antipsychotic Agents / Q000009:adverse effects*; D001569:Benzodiazepines / Q000009:adverse effects*; D004569:Electroencephalography; D005260:Female; D006801:Humans; D009207:Myoclonus / Q000139:chemically induced* / Q000503:physiopathology; D000077152:Olanzapine; D011618:Psychotic Disorders / Q000150:complications / Q000188:drug therapy
chemical_list: D014150:Antipsychotic Agents; D001569:Benzodiazepines; D000077152:Olanzapine