title: Outcomes analysis of anterior-posterior fusion for low grade isthmic spondylolisthesis.
abstract: BACKGROUND
  Traditional surgical treatment of isthmic spondylolisthesis is posterior-lateral fusion, but the addition of anterior surgery has been explored. The purpose of this study was to evaluate the surgical and clinical outcomes of anterior-posterior surgical treatment for low-grade isthmic spondylolisthesis.
  
  
  METHODS
  Retrospectively, we enrolled 23 consecutive patients (mean age of 50) who underwent surgical treatment for low grade isthmic spondylolisthesis. The mean follow-up was 10 months. Basic demographic and radiographic data was collected. Pre- and post-surgical clinical surveys (VAS, ODI, and SF-36) were collected.
  
  
  RESULTS
  All 23 patients underwent anterior interbody fusion with a femoral ring allograft or ICBG in combination with posterior lumbar decompression and fusion with instrumentation. The average slip percentage decreased from 23.2% to 19.0% (p = 0.24) while slip angle increased from 9.8° to 17.9° (p < 0.001) and average disc height decreased from 1.9 cm to 0.80 cm (p < 0.001). VAS scores decreased from 7.1 to 2.4 (p < 0.001), ODI scores decreased from 52.5 to 28.1 (p < 0.001), and SF-36 scores increased in the Physical Component Scale (PCS) from 29.5 to 42.6 (p < 0.001).
  
  
  CONCLUSIONS
  In our study, patients demonstrated an improvement in the ODI as well the physical component scores of the SF-36, thus having a good clinical outcome.
authors.affiliation: Department of Orthopaedic Surgery, NYU Hospital for Joint Diseases, New York, New York, USA. mquirno@gmail.com
authors.forename: Martin
authors.initials: M
authors.lastname: Quirno
authors.forename: Jonathan R
authors.initials: JR
authors.lastname: Kamerlink
authors.forename: Jeffrey A
authors.initials: JA
authors.lastname: Goldstein
authors.forename: Jeffrey M
authors.initials: JM
authors.lastname: Spivak
authors.forename: John A
authors.initials: JA
authors.lastname: Bendo
authors.forename: Thomas J
authors.initials: TJ
authors.lastname: Errico
mesh_terms: D000328:Adult; D000368:Aged; D016025:Bone Transplantation; D019299:Decompression, Surgical; D004185:Disability Evaluation; D005260:Female; D005269:Femur / Q000637:transplantation; D006801:Humans; D007085:Ilium / Q000637:transplantation; D008159:Lumbar Vertebrae / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009519:New York City; D011859:Radiography; D020127:Recovery of Function; D012189:Retrospective Studies; D012720:Severity of Illness Index; D013123:Spinal Fusion / Q000009:adverse effects; D013168:Spondylolisthesis / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery*; D011795:Surveys and Questionnaires; D013997:Time Factors; D016896:Treatment Outcome