title: Targeting the angiopoietin/Tie2 pathway: cutting tumor vessels with a double-edged sword?
authors.affiliation: The University of Texas MD Anderson Cancer Center, Unit 432, 1515 Holcombe Blvd, Houston, TX 77030, USA.
authors.forename: Tina
authors.initials: T
authors.lastname: Cascone
authors.forename: John V
authors.initials: JV
authors.lastname: Heymach
mesh_terms: D020533:Angiogenesis Inhibitors / Q000494:pharmacology* / Q000627:therapeutic use; D042682:Angiopoietins / Q000037:antagonists & inhibitors* / Q000378:metabolism; D000818:Animals; D006801:Humans; D058990:Molecular Targeted Therapy; D009369:Neoplasms / Q000098:blood supply* / Q000188:drug therapy* / Q000378:metabolism; D009389:Neovascularization, Pathologic / Q000188:drug therapy / Q000378:metabolism; D042787:Receptor, TIE-2 / Q000037:antagonists & inhibitors* / Q000378:metabolism; D015398:Signal Transduction / Q000187:drug effects
chemical_list: D020533:Angiogenesis Inhibitors; D042682:Angiopoietins; D042787:Receptor, TIE-2