title: Ex vivo comparison of Galileos cone beam CT and intraoral radiographs in detecting occlusal caries.
abstract: OBJECTIVE
  The aim of this study was to compare the accuracy of cone beam CT (CBCT) with intraoral radiographs for detection of occlusal caries.
  
  
  METHODS
  A set of 60 extracted teeth were imaged using a Sirona Galileos CBCT system (Sirona Dental Systems, Bensheim, Germany) and an intraoral Planmeca® system (Planmeca OY, Helsinki, Finland). Six observers looked at both modalities and used a five-point confidence scale to evaluate presence or absence of occlusal caries. Histology was used as the gold standard. Receiver operating characteristic analysis and weighted kappa statistics were used for statistical analysis. Differences in the area under the curve (AUC) values between observers and modalities were analysed using analysis of variance (ANOVA). Differences in sensitivity and specificity were analysed using the Wilcoxon test. Interobserver and intraobserver reliability was assessed by weighted kappa scores.
  
  
  RESULTS
  The mean value and standard deviation of AUC was 0.719 ± 0.038 for CBCT and 0.649 ± 0.062 for the intraoral radiographs. The ANOVA results demonstrated that there was no significant difference between the modalities and the observers. The interobserver kappa for pairs of observers ranged from fair to substantial for bitewings (0.244-0.543) and CBCT (0.152-0.401). Four out of six observers reported higher sensitivity but lower specificity with CBCT. The Wilcoxon exact p-value showed no difference in sensitivity (0.175) or specificity (0.573) between the two modalities.
  
  
  CONCLUSIONS
  Based on the results we conclude that the Sirona CBCT unit cannot be used for the sole purpose of looking at occlusal caries.
authors.affiliation: Department of Oral Pathology VCU School of Dentistry, Richmond, VA, USA. srathore@vcu.edu
authors.forename: S
authors.initials: S
authors.lastname: Rathore
authors.forename: D
authors.initials: D
authors.lastname: Tyndall
authors.forename: Jt
authors.initials: J
authors.lastname: Wright
authors.forename: E
authors.initials: E
authors.lastname: Everett
mesh_terms: D000704:Analysis of Variance; D019540:Area Under Curve; D054893:Cone-Beam Computed Tomography / Q000295:instrumentation*; D003731:Dental Caries / Q000000981:diagnostic imaging*; D006801:Humans; D066298:In Vitro Techniques; D012372:ROC Curve; D019252:Radiography, Dental, Digital / Q000295:instrumentation*; D012680:Sensitivity and Specificity