title: Evolution of the concept of biocompatibility and the cardioprotective effect of on-line hemodiafiltration.
abstract: Chronic inflammation presented by chronic kidney disease patients is accompanied by an increase in the percentage of CD14+/CD16+ monocytes. The inflammatory activity produced by these cells provokes the activation and death of endothelial cells, which suggests that these cells may play an important role in the coupling of inflammation and endothelial damage in these patients. Therefore, the reduction in CD14+/CD16+ inhibitory monocytes may constitute a therapeutic goal in the treatment of chronic kidney disease patients. The use of the most effective hemodialysis techniques such as on-line hemodiafiltration appears to be a suitable tool for achieving this objective.
authors.forename: Rafael
authors.initials: R
authors.lastname: Ramírez
authors.forename: Alejandro
authors.initials: A
authors.lastname: Martín-Malo
authors.forename: Pedro
authors.initials: P
authors.lastname: Aljama
mesh_terms: D001672:Biocompatible Materials; D002318:Cardiovascular Diseases / Q000209:etiology* / Q000276:immunology / Q000517:prevention & control*; D002908:Chronic Disease; D017583:Hemodiafiltration / Q000295:instrumentation / Q000379:methods*; D006801:Humans; D007249:Inflammation / Q000209:etiology / Q000276:immunology / Q000517:prevention & control; D007674:Kidney Diseases / Q000150:complications* / Q000276:immunology / Q000628:therapy*; D018950:Lipopolysaccharide Receptors / Q000378:metabolism; D009000:Monocytes / Q000276:immunology / Q000473:pathology; D017452:Receptors, IgG / Q000378:metabolism
chemical_list: D001672:Biocompatible Materials; D018950:Lipopolysaccharide Receptors; D017452:Receptors, IgG