title: Incidence of incomplete excision in surgically treated cutaneous squamous cell carcinoma and identification of the related risk factors.
abstract: Squamous cell carcinoma (SCC) is the second most common type of skin cancer with potential risks for metastasis and recurrence if left untreated or incompletely excised. This case series study was designed to determine the frequency of incompletely excised SCCs and the related risk factors. A total of 273 SCCs (253 patients) excised in Razi dermatology hospital of Tehran from 2006-2008, were evaluated and were analyzed by Chi-square or t-test. The incidence of incomplete excision was 17.58 % and deep margin involvement was observed in 73% of lesions. Risk factors associated with incomplete excision of SCCs were being female, location of the tumors (in particular the lesions on lateral canthus, upper lip, foot, forehead, cheek, neck, nose and ear), large lesions and grafting method of repair. There was no statistically significant difference for the age, degree of histological differentiation, childhood history of radiotherapy for tinea capitis and the type of anesthesia. More care should be taken for high risk SCCs as complete excision avoids potential risk of recurrence and metastasis.
authors.affiliation: Department of Dermatology, Razi Hospital, Tehran University of Medical Sciences, Iran.
authors.forename: Mostafa
authors.initials: M
authors.lastname: Mirshams
authors.forename: Mahmood
authors.initials: M
authors.lastname: Razzaghi
authors.forename: Pedram
authors.initials: P
authors.lastname: Noormohammadpour
authors.forename: Zahra
authors.initials: Z
authors.lastname: Naraghi
authors.forename: Kambiz
authors.initials: K
authors.lastname: Kamyab
authors.forename: Sara
authors.initials: S
authors.lastname: Sabouri Rad
mesh_terms: D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000601:surgery*; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D012878:Skin Neoplasms / Q000601:surgery*