title: The role of vitamin D in the immunopathogenesis of allergic skin diseases.
abstract: Vitamin D plays key roles in innate and adaptive immunity through the stimulation of Toll-like receptors, increasing pro-inflammatory cytokine production, and possibly enhancing T helper type 2 responses. These mechanisms may explain the growing body of evidence connecting vitamin D to allergic diseases, including asthma, food allergies, and allergic rhinitis. The data relating vitamin D to allergic skin diseases are equivocal with studies linking both high and low vitamin D levels to an increased risk of developing atopic dermatitis. In this paper, we describe the role of vitamin D in the immunopathogenesis of atopic dermatitis and other allergic skin diseases.
authors.affiliation: Albert Einstein College of Medicine, Bronx, New York, USA.
authors.forename: A A
authors.initials: AA
authors.lastname: Benson
authors.forename: J A
authors.initials: JA
authors.lastname: Toh
authors.forename: N
authors.initials: N
authors.lastname: Vernon
authors.forename: S P
authors.initials: SP
authors.lastname: Jariwala
mesh_terms: D000328:Adult; D000818:Animals; D002648:Child; D002675:Child, Preschool; D003876:Dermatitis, Atopic / Q000276:immunology* / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008297:Male; D051379:Mice; D014581:Urticaria / Q000276:immunology* / Q000503:physiopathology*; D014807:Vitamin D / Q000097:blood* / Q000276:immunology*
chemical_list: D014807:Vitamin D