title: [Perspectives on obsessive-compulsive spectrum disorders and its trends for the revision of DSM-5].
abstract: In the process of revising of DSM-5 for release in 2013, there is growing interest in the concept of a nosologically distinct spectrum of obsessive-compulsive disorders (OCSDs). Validity and compass of this spectrum remains to be fully elucidated, but a preliminary approach emphasizes that putative OCSDs have phenomenologic (eg. repetitive thoughts and/ or behaviors), etiological, psychobiologic or treatment overlap with OCD. Studies have investigated the relevant neurocircuitry, neurochemistry, and neuroendocrinology underlying anxiety disorders and OCSDs, and have explored the underlying genetic basis of and relevant intermediate phenotypes for developing these conditions. There appears to be some scientific validity and clinical utility for conceptualizing a subgroup of emotional-related disorders, within which fall the anxiety, posttraumatic, and OCSDs. However OCSDs, especially motoric OCSDs such as tic or Tourette's disorder still remain controversial; the appropriate grouping of these is still under discussion and may still change.
authors.affiliation: Department of Neuropsychiatry, Hyogo College of Medicine.
authors.forename: Hisato
authors.initials: H
authors.lastname: Matsunaga
mesh_terms: D039721:Diagnostic and Statistical Manual of Mental Disorders; D020022:Genetic Predisposition to Disease; D006801:Humans; D009448:Neurochemistry; D009452:Neuroendocrinology; D009771:Obsessive-Compulsive Disorder / Q000175:diagnosis / Q000209:etiology / Q000523:psychology / Q000628:therapy