title: [Antimicrobial sensitivity of Escherichia coli strains with K1 antigen isolated from pregnant women and newborns].
abstract: The aim of this study was comparison of the susceptibility to antibiotics of E. coli strains with K1 antigen (E. coli K1+) and non-K1 E. coli strains (E. coli K1-). This study included 67 of E. coli K1+ and 67 of E. coli K1- strains isolated in the time period from June to September of 2008 from pregnant women and newborns hospitalized at dr. J. Biziel University Hospital number 2 L. Rydygier Collegium Medicum in Bydgoszcz Nicolaus Copernicus University in Toruń. Antimicrobial susceptibility of E. coli strains was tested by the disc-diffusion method, on the Mueller Hinton 2 Agar (Becton Dickinson). It was found that 64,2% of E. coli K1+ strains and 53,7% of E. coli K1-strains were susceptible to all tested antibiotics and chemioterapeutics. E. coli K1- strains were more often than E. coli K1+ nonsusceptible to at least one antimicrobial agent. The obtained results indicate that E. coli K1+ strains significant differed in the susceptibility to ampicillin/sulbactam (85,1% versus 95,5%) (p=0,041), cephalothin (70,1% versus 85,1%) (p=0,038) and tetracycline (91,0% versus 74,6%) (p=0,012) from E. coli K1-strains. All tested E. coli K1+ and K1-strains were sensitive to piperacillin/tazobactam, cefoperazone/sulbactam, cefotaxime, ceftazidime, cefepime, imipenem, amikacin, netilmicin and tigecycline. There weren't the ESBL-producing strains among tested E. coli K1+ and K1- rods.
authors.affiliation: Katedra i Zakład Mikrobiologii, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy, Uniwersytetu Mikołaja Kopernika w Toruniu.
authors.forename: Agnieszka
authors.initials: A
authors.lastname: Kaczmarek
authors.forename: Anna
authors.initials: A
authors.lastname: Budzyńska
authors.forename: Eugenia
authors.initials: E
authors.lastname: Gospodarek
mesh_terms: D000328:Adult; D000942:Antigens, Bacterial; D016667:Bacterial Capsules / Q000276:immunology*; D024881:Drug Resistance, Bacterial / Q000276:immunology*; D004926:Escherichia coli / Q000187:drug effects* / Q000276:immunology* / Q000302:isolation & purification; D005260:Female; D006801:Humans; D007231:Infant, Newborn / Q000276:immunology*; D008826:Microbial Sensitivity Tests; D011135:Polysaccharides, Bacterial; D011247:Pregnancy / Q000276:immunology*
chemical_list: D000942:Antigens, Bacterial; D011135:Polysaccharides, Bacterial; C036962:capsular polysaccharide K1