title: Short communication: Effects of β-lactoglobulin, stearoyl-coenzyme A desaturase 1, and sterol regulatory element binding protein gene allelic variants on milk production, composition, acidity, and coagulation properties of Brown Swiss cows.
abstract: Associations of allelic variants of the β-lactoglobulin (LGB), stearoyl-coenzyme A desaturase 1 (SCD), and sterol regulatory element binding protein (SREBP-1) genes with milk production, composition (fat, protein, and casein content), acidity (pH and titratable acidity), and coagulation properties (rennet coagulation time and curd firmness) were investigated in Brown Swiss cows. In total, 294 animals (progeny of 15 sires) reared in 16 herds were milk-sampled once. The additive effects of LGB (rs109625649:C>T), SCD (ss469414220:C>T), and SREBP-1 (AB355704: g.101_185ins) polymorphisms on the aforementioned traits were analyzed through Bayesian linear models. The LGB genotype affected rennet coagulation time, with TT (or BB) alleles showing longer rennet coagulation time compared with CC (or AA) cows. The SCD gene allelic variants were found to be associated with protein and casein contents and curd firmness: CC animals had the lowest values for the aforementioned traits. An association was found between SREBP-1 alleles and fat content, with the highest values for cows carrying the 84-bp insertion (or L) allele. Results suggest a possible use of these loci in gene-assisted selection programs for the improvement of milk quality traits and coagulation properties in Brown Swiss cattle.
authors.affiliation: Department of Animal Science, University of Padova, Legnaro (PD), Italy. alessio.cecchinato@unipd.it
authors.forename: A
authors.initials: A
authors.lastname: Cecchinato
authors.forename: C
authors.initials: C
authors.lastname: Ribeca
authors.forename: A
authors.initials: A
authors.lastname: Maurmayr
authors.forename: M
authors.initials: M
authors.lastname: Penasa
authors.forename: M
authors.initials: M
authors.lastname: De Marchi
authors.forename: N P P
authors.initials: NP
authors.lastname: Macciotta
authors.forename: M
authors.initials: M
authors.lastname: Mele
authors.forename: P
authors.initials: P
authors.lastname: Secchiari
authors.forename: G
authors.initials: G
authors.lastname: Pagnacco
authors.forename: G
authors.initials: G
authors.lastname: Bittante
mesh_terms: D000483:Alleles; D000818:Animals; D002417:Cattle / Q000235:genetics; D005260:Female; D056726:Genetic Association Studies / Q000662:veterinary; D014644:Genetic Variation; D005838:Genotype; D006863:Hydrogen-Ion Concentration; D007774:Lactation / Q000235:genetics*; D007782:Lactoglobulins / Q000235:genetics*; D008892:Milk / Q000737:chemistry* / Q000378:metabolism; D008894:Milk Proteins / Q000032:analysis; D011110:Polymorphism, Genetic / Q000235:genetics; D013230:Stearoyl-CoA Desaturase / Q000235:genetics*; D051779:Sterol Regulatory Element Binding Proteins / Q000235:genetics*
chemical_list: D007782:Lactoglobulins; D008894:Milk Proteins; D051779:Sterol Regulatory Element Binding Proteins; D013230:Stearoyl-CoA Desaturase