title: [Taking into account the emotional tension of adults and children in the evaluation of the influence of environmental factors on genomic instability and sensitivity: results and prospects].
abstract: The paper summarizes the results of 8 genetic and psychological examinations in adults and children, which are aimed at evaluating the genotoxic effects of environmental factors on cultured lymphocytes. Human emotional tension was proved to be directly related to the level of genome damage, to genomic sensitivity to in vitro exposures, and to lymphocyte proliferative activity and to be inversely related to the level of apoptosis. There was an association of the degree of anxiety in children with their morbidity. High emotional tension in adult family members was found to negatively affect the degree of anxiety and the level of genomic instability in a child.
authors.forename: F I
authors.initials: FI
authors.lastname: Ingel'
authors.forename: E K
authors.initials: EK
authors.lastname: Krivtsova
authors.forename: N A
authors.initials: NA
authors.lastname: Iurtseva
authors.forename: V V
authors.initials: VV
authors.lastname: Iurchenko
authors.forename: Sh N
authors.initials: ShN
authors.lastname: Khusainova
authors.forename: G A
authors.initials: GA
authors.lastname: Kosdauletova
authors.forename: T B
authors.initials: TB
authors.lastname: Legostaeva
authors.forename: B M
authors.initials: BM
authors.lastname: Antsiferov
authors.forename: S I
authors.initials: SI
authors.lastname: Ivanov
authors.forename: O B
authors.initials: OB
authors.lastname: Kozlova
mesh_terms: D000328:Adult; D017209:Apoptosis / Q000187:drug effects; D049109:Cell Proliferation / Q000187:drug effects; D002648:Child; D002675:Child, Preschool; D002869:Chromosome Aberrations / Q000139:chemically induced* / Q000706:statistics & numerical data; D004785:Environmental Pollutants / Q000633:toxicity*; D042822:Genomic Instability / Q000187:drug effects*; D006801:Humans; D008214:Lymphocytes / Q000187:drug effects / Q000648:ultrastructure; D048629:Micronuclei, Chromosome-Defective / Q000139:chemically induced / Q000706:statistics & numerical data; D012426:Russia / Q000453:epidemiology; D013315:Stress, Psychological / Q000097:blood / Q000453:epidemiology / Q000235:genetics*
chemical_list: D004785:Environmental Pollutants