title: Three rhodamine-based "off-on" chemosensors with high selectivity and sensitivity for Fe3+ imaging in living cells.
abstract: Three new rhodamine-based probes Y1-Y3 were synthesized as "off-on" chemosensors for Fe(3+) imaging in living cells. The recognizing behaviors were investigated both experimentally and computationally. The crystal structure of the complex Y3-Fe(3+) revealed that Fe(3+) preferred to coordinate with the N atom of benzothiazole moiety rather than the O atom of carboxyl group.
authors.affiliation: Ministry of Education Key Laboratory of Synthetic and Natural Functional Molecule Chemistry, College of Chemistry & Materials Science, Northwest University, Xi'an, Shaanxi 710069, PR China.
authors.forename: Zheng
authors.initials: Z
authors.lastname: Yang
authors.forename: Mengyao
authors.initials: M
authors.lastname: She
authors.forename: Bing
authors.initials: B
authors.lastname: Yin
authors.forename: Jihong
authors.initials: J
authors.lastname: Cui
authors.forename: Yuze
authors.initials: Y
authors.lastname: Zhang
authors.forename: Wei
authors.initials: W
authors.lastname: Sun
authors.forename: Jianli
authors.initials: J
authors.lastname: Li
authors.forename: Zhen
authors.initials: Z
authors.lastname: Shi
mesh_terms: D052160:Benzothiazoles / Q000737:chemistry; D002623:Chemistry Techniques, Analytical / Q000379:methods; D005290:Ferric Compounds / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000737:chemistry*; D006367:HeLa Cells / Q000378:metabolism; D006801:Humans; D007501:Iron / Q000032:analysis*; D008855:Microscopy, Electron, Scanning / Q000379:methods; D057054:Molecular Imaging / Q000379:methods; D009584:Nitrogen / Q000737:chemistry; D010100:Oxygen / Q000737:chemistry; D012235:Rhodamines / Q000737:chemistry*; D012680:Sensitivity and Specificity; D013055:Spectrophotometry, Infrared
chemical_list: D052160:Benzothiazoles; D005290:Ferric Compounds; D005456:Fluorescent Dyes; D012235:Rhodamines; D007501:Iron; C005465:benzothiazole; D009584:Nitrogen; D010100:Oxygen