title: Noninvasive observations of peripheral angle in eyes after penetrating keratoplasty using anterior segment fourier-domain optical coherence tomography.
abstract: OBJECTIVE
  To examine iridotrabecular contact (ITC) as a peripheral anterior synechia (PAS) of patients who underwent penetrating keratoplasty (PKP) using anterior segment Fourier-domain optical coherence tomography (OCT).
  
  
  METHODS
  Retrospective, observational case series. ITC, ITC index, and ITC area of 60 eyes of 52 patients who underwent PKP at the Department of Ophthalmology in the University of Tokyo Hospital (mean follow-up time 102.8 ± 116.1 months postoperation) were calculated using the angle analysis mode of a commercially available anterior segment Fourier-domain OCT system (CASIA; TOMEY, Nagoya, Japan). We analyzed the occurrence of ITC, ITC index, and ITC area with preoperative diagnosis, lens status, operation method, operation frequency, graft size, and intraocular pressure elevation.
  
  
  RESULTS
  ITC was observed in 28 (46.7%) of 60 eyes. Average ITC index was 14.0%, and average ITC area was 5.97 mm. ITC was significantly associated with eyes with bullous keratopathy, infectious keratitis, pseudophakia, PKP with cataract operation, several PKP operations, and large graft size.
  
  
  CONCLUSIONS
  Anterior segment Fourier-domain OCT is a useful and innovative tool that enables us to observe the anterior chamber angle and examine ITC as PAS of eyes with corneal opacity, even after PKP.
authors.affiliation: Department of Ophthalmology, University of Tokyo School of Medicine, Tokyo, Japan.
authors.forename: Reina
authors.initials: R
authors.lastname: Fukuda
authors.forename: Tomohiko
authors.initials: T
authors.lastname: Usui
authors.forename: Atsuo
authors.initials: A
authors.lastname: Tomidokoro
authors.forename: Koichi
authors.initials: K
authors.lastname: Mishima
authors.forename: Naomi
authors.initials: N
authors.lastname: Matagi
authors.forename: Takashi
authors.initials: T
authors.lastname: Miyai
authors.forename: Shiro
authors.initials: S
authors.lastname: Amano
authors.forename: Makoto
authors.initials: M
authors.lastname: Araie
mesh_terms: D000368:Aged; D000869:Anterior Eye Segment / Q000473:pathology*; D003316:Corneal Diseases / Q000175:diagnosis* / Q000601:surgery; D005260:Female; D005583:Fourier Analysis; D005901:Glaucoma / Q000473:pathology* / Q000601:surgery*; D006801:Humans; D015948:Keratoplasty, Penetrating / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D041623:Tomography, Optical Coherence / Q000379:methods*; D014129:Trabecular Meshwork / Q000473:pathology