title: Overactive bladder: diagnosis and management.
abstract: Overactive bladder (OAB) is a clinical syndrome describing the symptom complex of urgency, with or without urgency incontinence and is usually associated with frequency and nocturia. Whilst a number of women may be managed based on a clinical diagnosis alone urodynamic studies may be useful in those women with complex or refractory symptoms. In the first instance all women will benefit from a conservative approach using bladder retraining although a number will require antimuscarinic therapy. For those women with persistent symptoms following medical therapy alternative treatment modalities such as intravesical Botulinum Toxin, neuromodulation or reconstructive surgery may be considered. This review, whilst giving an overview of the syndrome, will focus on a practical clinical approach to managing women with symptoms of overactive bladder (OAB).
authors.affiliation: Department of Urogynaecology, Kings College Hospital, London, UK. dudley.robinson@nhs.net
authors.forename: Dudley
authors.initials: D
authors.lastname: Robinson
authors.forename: Linda
authors.initials: L
authors.lastname: Cardozo
mesh_terms: D001905:Botulinum Toxins / Q000627:therapeutic use; D005081:Exercise Therapy; D005260:Female; D006801:Humans; D018727:Muscarinic Antagonists / Q000627:therapeutic use; D053201:Urinary Bladder, Overactive / Q000175:diagnosis* / Q000628:therapy*
chemical_list: D018727:Muscarinic Antagonists; D001905:Botulinum Toxins