title: Hepatic necrosis: a main presentation of systemic lupus erythematosus in a previously healthy woman.
abstract: Systemic lupus erythematosus (SLE) is a chronic inflammatory disease of unknown cause. In this study, we report a case of SLE that was presented with persistent vomiting and liver involvement. To our knowledge, this is the first description of a patient with hepatic necrosis as the initial presentation of SLE in a previously healthy woman without any significant past medical history. In the literature, we found few cases of SLE with liver necrosis. In addition, all the cases found had a past medical history of a missed abortion or other complications of the disease. Therefore, if a young woman presents hepatic necrosis with a background of a previously missed abortion, it is better to perform anti-nuclear antibody (ANA) and anticardiolipin antibody tests as a preventive method for early diagnosis and early treatment.
authors.affiliation: Department of Infectious and Tropical Diseases, Isfahan University of Medical Sciences, Isfahan, Iran.
authors.forename: Majid
authors.initials: M
authors.lastname: Avijgan
authors.forename: Mohsen
authors.initials: M
authors.lastname: Meidani
authors.forename: Mansour
authors.initials: M
authors.lastname: Salesi
authors.forename: Farshid
authors.initials: F
authors.lastname: Rezaei