title: Epigenetics and metabolism in 2011: Epigenetics, the life-course and metabolic disease.
abstract: Clinical and experimental studies suggest that early life experiences, perhaps spanning multiple generations, affect lifelong risk of metabolic dysfunction through epigenetic mechanisms. Data published in 2011 suggest that epigenetic analysis could potentially have utility as a marker of early metabolic pathology and might enable early life prophylaxis.
authors.affiliation: Liggins Institute, The University of Auckland, Private Bag 92019, Auckland 1142, New Zealand. pd.gluckman@auckland.ac.nz
authors.forename: Peter D
authors.initials: PD
authors.lastname: Gluckman
mesh_terms: D019175:DNA Methylation / Q000235:genetics / Q000502:physiology; D003924:Diabetes Mellitus, Type 2 / Q000235:genetics; D004704:Endocrinology / Q000379:methods / Q000639:trends*; D044127:Epigenesis, Genetic / Q000502:physiology*; D006801:Humans; D019369:Life; D008659:Metabolic Diseases / Q000453:epidemiology / Q000235:genetics*; D008660:Metabolism / Q000235:genetics*; D013997:Time Factors