title: [Advanced endometrial carcinoma: primary debulking surgery or neoadjuvant chemotherapy?].
abstract: Endometrial cancers with peritoneal spread are stage IVB of FIGO classification. Their pattern is similar to that of ovarian cancer. Optimal debulking surgery and chemotherapy are predictor of better overall and disease free survival. Despite the poor outcome, there is a need for new treatment options. Recommended management for this group of patients should consist of surgical cytoreduction followed by chemotherapy. There may be a role for neoadjuvant chemotherapy followed by interval surgery in selected subgroups of patients.
authors.affiliation: Institut Bergonié, CLCC Aquitaine, département d'oncogynécologie, Bordeaux Cedex, France. guyon@bergonie.org
authors.forename: Frédéric
authors.initials: F
authors.lastname: Guyon
authors.forename: Eberhard
authors.initials: E
authors.lastname: Stoeckle
authors.forename: Laurence
authors.initials: L
authors.lastname: Thomas
authors.forename: Adeline
authors.initials: A
authors.lastname: Petit
authors.forename: Marie
authors.initials: M
authors.lastname: Sire
authors.forename: Anne
authors.initials: A
authors.lastname: Floquet
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use; D017024:Chemotherapy, Adjuvant / Q000379:methods; D016889:Endometrial Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D020360:Neoadjuvant Therapy / Q000379:methods*; D009367:Neoplasm Staging / Q000379:methods; D047368:Tumor Burden
chemical_list: D000970:Antineoplastic Agents