title: Pd-Catalyzed asymmetric hydrogenation of 3-(toluenesulfonamidoalkyl)indoles.
abstract: A series of 2-substituted 3-(toluenesulfonamidoalkyl)indoles was synthesized by application of (EtO)(2)POH or iodine as the catalyst, and was hydrogenated using chiral Pd catalyst, giving the 2,3-disubstituted indolines with up to 97% ee.
authors.affiliation: State Key Laboratory of Catalysis, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, 457 Zhongshan Road, Dalian 116023, PR China.
authors.forename: Ying
authors.initials: Y
authors.lastname: Duan
authors.forename: Mu-Wang
authors.initials: MW
authors.lastname: Chen
authors.forename: Qing-An
authors.initials: QA
authors.lastname: Chen
authors.forename: Chang-Bin
authors.initials: CB
authors.lastname: Yu
authors.forename: Yong-Gui
authors.initials: YG
authors.lastname: Zhou
mesh_terms: D002384:Catalysis; D006865:Hydrogenation; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D007211:Indoles; D009942:Organometallic Compounds; D010165:Palladium