title: Effect of drilling dimension on implant placement torque and early osseointegration stages: an experimental study in dogs.
abstract: OBJECTIVE
  Primary stability has been regarded as a key factor to ensure uneventful osseointegration of dental implants. Such stability is often achieved by placing implants in undersized drilled bone. The present study evaluated the effect of drilling dimensions in insertion torque and early implant osseointegration stages in a beagle dog model.
  
  
  METHODS
  Six beagle dogs were acquired and subjected to bilateral surgeries in the radii 1 and 3 weeks before death. During surgery, 3 implants, 4 mm in diameter by 10 mm in length, were placed in bone sites drilled to 3.2 mm, 3.5 mm, and 3.8 mm in diameter. The insertion torque was recorded for all samples. After death, the implants in bone were nondecalcified processed and morphologically and morphometrically (bone-to-implant contact and bone area fraction occupancy) evaluated. Statistical analyses were performed using the Kruskal-Wallis test followed by Dunn's post hoc test for multiple comparisons at the 95% level of significance.
  
  
  RESULTS
  The insertion torque levels obtained were inversely proportional to the drilling dimension, with a significant difference detected between the 3.2-mm and 3.8-mm groups (P = .003). Despite a significant increase in the bone-to-implant contact over time in vivo for all groups (P = .007), no effect for the drilling dimension was observed. Additionally, no effect of the drilling dimension and time was observed for the bone area fraction occupancy parameter (P = .31). The initial healing pathways differed between implants placed in bone drilled to different dimensions.
  
  
  CONCLUSIONS
  Although different degrees of torque were observed with different drilling dimensions and these resulted in different healing patterns, no differences in the histometrically evaluated parameters were observed.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Universidade Federal de Uberlandia, Minas Gerias, Brazil.
authors.forename: Felipe E
authors.initials: FE
authors.lastname: Campos
authors.forename: Julio B
authors.initials: JB
authors.lastname: Gomes
authors.forename: Charles
authors.initials: C
authors.lastname: Marin
authors.forename: Hellen S
authors.initials: HS
authors.lastname: Teixeira
authors.forename: Marcelo
authors.initials: M
authors.lastname: Suzuki
authors.forename: Lukasz
authors.initials: L
authors.lastname: Witek
authors.forename: Darceny
authors.initials: D
authors.lastname: Zanetta-Barbosa
authors.forename: Paulo G
authors.initials: PG
authors.lastname: Coelho
mesh_terms: D000134:Acid Etching, Dental; D000818:Animals; D016723:Bone Remodeling / Q000502:physiology; D004396:Coloring Agents; D045662:Dental Etching; D003758:Dental Implantation, Endosseous / Q000379:methods*; D015921:Dental Implants; D017267:Dental Prosthesis Design; D017268:Dental Prosthesis Retention; D004285:Dogs; D007091:Image Processing, Computer-Assisted / Q000379:methods; D008297:Male; D009336:Necrosis; D016348:Osseointegration / Q000502:physiology*; D010012:Osteogenesis / Q000502:physiology; D010027:Osteotomy / Q000379:methods*; D011884:Radius / Q000473:pathology / Q000601:surgery; D013499:Surface Properties; D013997:Time Factors; D014048:Tolonium Chloride; D019415:Torque
chemical_list: D004396:Coloring Agents; D015921:Dental Implants; D014048:Tolonium Chloride