title: Nosocomial infection following video-assisted thoracoscopic surgery.
abstract: OBJECTIVE
  To assess the incidence and risk factors for nosocomial infection after video-assisted thoracic surgery (VATS).
  
  
  METHODS
  Prospective cohort study of all consecutive patients who underwent VATS surgery during 20 months. Patients were visited on a daily basis and followed up until they were discharged from the hospital.
  
  
  RESULTS
  During the study period 217 patients (70.1% men; mean age, 50.9 years, range 15-85 years) underwent VATS. Fourteen (6%) episodes of postoperative infection were diagnosed in 13 patients, including pneumonia (n = 2), lower respiratory tract infection (n = 9), surgical site infection (n = 2), and urinary tract infection (n = 1). Prior inmunosupresion (adjusted odds ratio [OR], 2.70; 95% confidence interval [CI], 1.52-4.84), prior infections (OR, 14.9; 95% CI 1.91-116.5), preoperative stay > 2 days (OR, 3.37; 95% CI 1.00-11.40), neoplasia (OR, 3.69; 95% CI, 1.94-7.06) duration of surgery > 45 minutes (OR, 5.91; 95% CI, 1.00-36.40) and presence of central venous catheter (OR, 16.40; 95% CI, 2.29-117.20), were independent risk factors for nosocomial infection.
  
  
  CONCLUSIONS
  Nosocomial infection rate after VATS was low. Respiratory infection was the most common infection. Factors which affect patient immunity, preoperative stay and perioperative-related variables were independently associated with infection.
authors.affiliation: Infectious Diseases Unit, Department of Internal Medicine, Hospital Universitario Marqués de Valdecilla, Universidad de Cantabria, Santander, Cantabria.
authors.forename: Daniel Narcis
authors.initials: DN
authors.lastname: Nan
authors.forename: Marta
authors.initials: M
authors.lastname: Fernández-Ayala
authors.forename: Concepción
authors.initials: C
authors.lastname: Fariñas-Álvarez
authors.forename: Roberto
authors.initials: R
authors.lastname: Mons
authors.forename: Jesús
authors.initials: J
authors.lastname: González-Macías
authors.forename: María Carmen
authors.initials: MC
authors.lastname: Fariñas
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D019072:Antibiotic Prophylaxis / Q000706:statistics & numerical data; D016001:Confidence Intervals; D003428:Cross Infection / Q000453:epidemiology* / Q000209:etiology*; D003625:Data Collection; D003627:Data Interpretation, Statistical; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D011183:Postoperative Complications / Q000453:epidemiology* / Q000209:etiology*; D011446:Prospective Studies; D012307:Risk Factors; D012737:Sex Factors; D012907:Smoking / Q000009:adverse effects; D013030:Spain / Q000453:epidemiology; D020775:Thoracic Surgery, Video-Assisted / Q000009:adverse effects*; D055815:Young Adult
chemical_list: D007166:Immunosuppressive Agents