title: Hypertrophic osteopathy associated with pulmonary adenosquamous carcinoma in a dog.
abstract: A six-year-old intact female Maltese dog weighing 3.8 kg presented with a history of mild lameness and swelling on both forelimbs. Radiographic and computed tomographic views revealed an extensive periosteal reaction in all four limbs and a large round mass on the right middle lung lobe. A total lobectomy was performed and pulmonary adenosquamous carcinoma was histologically confirmed. A diagnosis of hypertrophic osteopathy (HO) secondary to a lung tumor was made. Periosteal proliferation decreased significantly after surgery; however, there was evidence of dyspnea, mass recurrence, and periosteal reaction three months post-operatively. This is the first case report of pulmonary adenosquamous carcinoma with HO in a dog in which we describe clinical, imaging, surgical, and histological findings.
authors.affiliation: Department of Veterinary Surgery, College of Veterinary Medicine, Konkuk University, 1 Hwayang-dong, Kwangjin-gu, Seoul 143-701, Korea.
authors.forename: Jung-Ha
authors.initials: JH
authors.lastname: Lee
authors.forename: Jong-Hoon
authors.initials: JH
authors.lastname: Lee
authors.forename: Hun-Young
authors.initials: HY
authors.lastname: Yoon
authors.forename: Na-Hyun
authors.initials: NH
authors.lastname: Kim
authors.forename: Jung-Hyang
authors.initials: JH
authors.lastname: Sur
authors.forename: Soon-Wuk
authors.initials: SW
authors.lastname: Jeong
mesh_terms: D000818:Animals; D018196:Carcinoma, Adenosquamous / Q000150:complications / Q000473:pathology / Q000601:surgery / Q000662:veterinary*; D004283:Dog Diseases / Q000209:etiology / Q000473:pathology* / Q000601:surgery; D004285:Dogs; D005260:Female; D015576:Hyperostosis / Q000209:etiology / Q000662:veterinary*; D008175:Lung Neoplasms / Q000150:complications / Q000473:pathology / Q000601:surgery / Q000662:veterinary*