title: Preoperative liquid embolization of cerebeller hemangioblastomas using N-butyl cyanoacrylate.
abstract: BACKGROUND
  We aim to present and discuss clinical outcomes of preoperative liquid embolization of hemangioblastomas (HB) using N-butyl cyanoacrylate (NBCA).
  
  
  METHODS
  From 1999 through 2010, 19 patients presenting with symptoms of vertigo and/or headaches were diagnosed with HB based on preoperative magnetic resonance imaging and cerebral angiographic findings at our institution. Preoperative embolization with NBCA was performed on tumors in 10 of 21 operations for 19 patients. For each of these patients, the lesion was pathologically confirmed as HB.
  
  
  RESULTS
  Embolization had a favorable outcome in all patients. No permanent neurological complications were observed after preoperative embolization using NBCA. However, thalamic infarction and minor hemorrhage were observed in two patients with cerebellar HB.
  
  
  CONCLUSIONS
  The authors recommend NBCA as an embolization material for large cerebellar HB.
authors.affiliation: Department of Neurosurgery, Nippon Medical School, Sendagi, Bunkyo-ku, Tokyo 113-86, Japan. ymurai@nms.ac.jp
authors.forename: Yasuo
authors.initials: Y
authors.lastname: Murai
authors.forename: Shushi
authors.initials: S
authors.lastname: Kominami
authors.forename: Yoichi
authors.initials: Y
authors.lastname: Yoshida
authors.forename: Takayuki
authors.initials: T
authors.lastname: Mizunari
authors.forename: Koji
authors.initials: K
authors.lastname: Adachi
authors.forename: Kenta
authors.initials: K
authors.lastname: Koketsu
authors.forename: Shiro
authors.initials: S
authors.lastname: Kobayashi
authors.forename: Akira
authors.initials: A
authors.lastname: Teramoto
mesh_terms: D000328:Adult; D000368:Aged; D002528:Cerebellar Neoplasms / Q000628:therapy*; D002533:Cerebral Angiography; D004621:Embolization, Therapeutic / Q000379:methods*; D004659:Enbucrilate / Q000627:therapeutic use*; D005260:Female; D018325:Hemangioblastoma / Q000628:therapy*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome
chemical_list: D004659:Enbucrilate