title: Porencephaly and hydranencephaly in six dogs.
abstract: A retrospective study was performed to identify dogs with cerebrospinal fluid-filled cavitatory lesions on MRI. Six dogs were included and the lesions were classified. In the three dogs in the present study with hydranencephaly, unilateral but complete loss of the temporal and parietal lobes was noted and had almost complete loss of the occipital and frontal lobes of a cerebral hemisphere. In the three dogs with porencephaly, there was unilateral incomplete loss of the parietal lobe and one dog had additional partial loss of the temporal and frontal lobes. Two of the dogs with porencephaly had seizures; the third showed no associated clinical signs. The dogs with hydranencephaly had mentation changes and circled compulsively. The two porencephalic dogs with seizures were treated with phenobarbitone. One of the dogs with hydranencephaly showed increased frequency and duration of circling; one dog's clinical signs did not progress and the third dog was euthanased due to increasing aggression. The dog with increased circling had ventriculoperitoneal shunt placement and the circling frequency reduced.
authors.affiliation: Willows Veterinary Centre, Highlands Road, Shirley, Solihull, West Midlands B90 4NH, UK. edavies@rvc.ac.uk
authors.forename: E S S
authors.initials: ES
authors.lastname: Davies
authors.forename: H A
authors.initials: HA
authors.lastname: Volk
authors.forename: S
authors.initials: S
authors.lastname: Behr
authors.forename: B
authors.initials: B
authors.lastname: Summers
authors.forename: A
authors.initials: A
authors.lastname: de Lahunta
authors.forename: H
authors.initials: H
authors.lastname: Syme
authors.forename: P
authors.initials: P
authors.lastname: Jull
authors.forename: L
authors.initials: L
authors.lastname: Garosi
mesh_terms: D000818:Animals; D002526:Cerebellar Diseases / Q000175:diagnosis / Q000473:pathology / Q000628:therapy / Q000662:veterinary*; D002531:Cerebellum / Q000002:abnormalities / Q000473:pathology; D004283:Dog Diseases / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D004285:Dogs; D005260:Female; D006832:Hydranencephaly / Q000175:diagnosis / Q000473:pathology / Q000628:therapy / Q000662:veterinary*; D008297:Male; D010634:Phenobarbital / Q000627:therapeutic use; D065708:Porencephaly; D012189:Retrospective Studies; D012640:Seizures / Q000188:drug therapy / Q000209:etiology / Q000662:veterinary*; D016896:Treatment Outcome; D017287:Ventriculoperitoneal Shunt / Q000662:veterinary
chemical_list: D010634:Phenobarbital