title: Palladium-catalyzed oxidative aryltrifluoromethylation of activated alkenes at room temperature.
abstract: A palladium-catalyzed intramolecular oxidative aryltrifluoromethylation reaction of activated alkenes has been explored. The reaction allows for an efficient synthesis of a variety of CF(3)-containing oxindoles. Preliminary mechanistic study indicated that the reaction involves a C(sp(3))-Pd(IV)(CF(3)) intermediate, which undergoes reductive elimination to afford a C(sp(3))-CF(3) bond.
authors.affiliation: State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, China.
authors.forename: Xin
authors.initials: X
authors.lastname: Mu
authors.forename: Tao
authors.initials: T
authors.lastname: Wu
authors.forename: Hao-yang
authors.initials: HY
authors.lastname: Wang
authors.forename: Yin-long
authors.initials: YL
authors.lastname: Guo
authors.forename: Guosheng
authors.initials: G
authors.lastname: Liu
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D002384:Catalysis; D015394:Molecular Structure; D010084:Oxidation-Reduction; D010165:Palladium / Q000737:chemistry*; D013696:Temperature
chemical_list: D000475:Alkenes; D010165:Palladium