title: High grade angiosarcoma arising in fibroadenoma.
abstract: Primary angiosarcoma of the breast is a rare tumour that account for fewer than 0.05% of all malignant mammary tumours. Angiosarcoma may have an perfidious clinical onset. Radiologic findings are often nonspecific and may appear completely normal in one-third of cases with primary angiosarcoma. The prognosis is usually poor because of the high rates of local recurrence and early development of metastases. Aggressive surgical resection is the mainstay of treatment. The role of adjuvant therapy has not yet been well established. Here we present a case of a 53 year old, postmenopausal women with primary angiosarcoma arising in fibroadenoma. To our knowledge, this is the first case described in the literature to date.
authors.affiliation: Department of Pathology, School of Medicine, University of Rijeka, Braće Branchetta 20, Rijeka, Croatia. esinozic@gmail.com
authors.forename: Emina
authors.initials: E
authors.lastname: Babarović
authors.forename: Gordana
authors.initials: G
authors.lastname: Zamolo
authors.forename: Elvira
authors.initials: E
authors.lastname: Mustać
authors.forename: Miroslav
authors.initials: M
authors.lastname: Strčić
mesh_terms: D001943:Breast Neoplasms / Q000473:pathology*; D005260:Female; D018226:Fibroadenoma / Q000473:pathology*; D006394:Hemangiosarcoma / Q000473:pathology*; D006801:Humans; D008875:Middle Aged; D060787:Neoplasm Grading; D016609:Neoplasms, Second Primary / Q000473:pathology*