title: Impact of perinatal somatic and common mental disorder symptoms on functioning in Ethiopian women: the P-MaMiE population-based cohort study.
abstract: BACKGROUND
  Little is known of the relationship between perinatal somatic and common mental disorder (CMD) symptoms and impaired functioning in women from settings where the burden of undernutrition and infectious disease morbidity is high.
  
  
  METHODS
  A population-based sample of 1065 women from Butajira, Ethiopia, was recruited in pregnancy (86.4% of those eligible) and reassessed two months postnatal (954 with singleton, live infants). At both time-points, women were administered a modified version of the Patient Health Questionnaire-15 and the Self-Reporting Questionnaire (locally-validated) to assess somatic and CMD symptoms, respectively. Negative binomial regression was used to investigate associations of CMD and somatic symptoms with functional impairment (World Health Organisation Disability Assessment Scale, version-II), after adjusting for maternal anthropometric measures, physical ill-health and sociodemographic factors.
  
  
  RESULTS
  In pregnancy, somatic and CMD symptoms were independently associated with worse maternal functional impairment after adjustment for confounders (WHODAS-II score multiplied by 1.09 (95%CI 1.06, 1.13) and 1.11 (95%CI 1.08, 1.14) respectively for each additional symptom). In the postnatal period, the size of association between somatic symptoms and functional impairment was diminished, but the association with CMD symptoms was virtually unchanged (multiplier value 1.04 (95%CI 1.00, 1.09) and 1.11 (95%CI 1.07, 1.16) respectively).
  
  
  CONCLUSIONS
  Use of largely self-report measures.
  
  
  CONCLUSIONS
  Somatic and CMD symptoms were independently associated with functional impairment in both pregnancy and the postnatal period, with CMD symptoms showing a stronger and more consistent association. This emphasises the public health relevance of both CMD and somatic symptoms in the perinatal period.
authors.affiliation: King's College London, Institute of Psychiatry, London, United Kingdom.
authors.forename: Vesile
authors.initials: V
authors.lastname: Senturk
authors.forename: Charlotte
authors.initials: C
authors.lastname: Hanlon
authors.forename: Girmay
authors.initials: G
authors.lastname: Medhin
authors.forename: Michael
authors.initials: M
authors.lastname: Dewey
authors.forename: Mesfin
authors.initials: M
authors.lastname: Araya
authors.forename: Atalay
authors.initials: A
authors.lastname: Alem
authors.forename: Martin
authors.initials: M
authors.lastname: Prince
authors.forename: Robert
authors.initials: R
authors.lastname: Stewart
mesh_terms: D000328:Adult; D015331:Cohort Studies; D003141:Communicable Diseases / Q000175:diagnosis / Q000453:epidemiology*; D005002:Ethiopia; D005260:Female; D006304:Health Status; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D044342:Malnutrition / Q000175:diagnosis / Q000453:epidemiology*; D001523:Mental Disorders / Q000175:diagnosis / Q000453:epidemiology*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis / Q000453:epidemiology*; D012307:Risk Factors; D011795:Surveys and Questionnaires; D055815:Young Adult