title: Tonsil amyloidosis revealing a Waldenström macroglobulinemia.
abstract: Localized amyloidosis of the tonsil is rare and its management depends on the etiology. We report a case of tonsil amyloidosis and review the characteristics of this exceptional pathology. A 74-year-old man consulted for odynophagia, upper dysphagia and deteriorated general health status, which have been evolving for 1 year. Clinical examination found a smooth swelling of the right palatine tonsil. No further abnormalities were noted. The biopsy findings were consistent with amyloidosis. Etiological assessment pointed to Waldenstrom macroglobulinemia. Tonsillectomy was performed. The patient was managed by chemotherapy associating chlorambucil, vincristine and prednisone. The progress after chemotherapy was good. Localized amyloidosis is a rare lesion of the superior aerodigestive tract, predominating in the larynx and tonsil involvement is exceptional. Its diagnosis is histological and its management depends on the etiology. Continued regular follow-up is necessary to look for recurrence.
authors.affiliation: Départment of Internal Medicine, Hédi Chaker University Hospital, 3029 Sfax, Tunisia. raidabensalah@yahoo.fr
authors.forename: Raida
authors.initials: R
authors.lastname: Ben Salah
authors.forename: Sameh
authors.initials: S
authors.lastname: Marzouk
authors.forename: Neila
authors.initials: N
authors.lastname: Kaddour
authors.forename: Abdelmajid
authors.initials: A
authors.lastname: Khabir
authors.forename: Tahia
authors.initials: T
authors.lastname: Boudawara
authors.forename: Zouhir
authors.initials: Z
authors.lastname: Bahloul
mesh_terms: D000368:Aged; D000686:Amyloidosis / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D003680:Deglutition Disorders / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery; D003937:Diagnosis, Differential; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D014066:Palatine Tonsil / Q000473:pathology* / Q000601:surgery; D010608:Pharyngeal Diseases / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D014068:Tonsillectomy; D008258:Waldenstrom Macroglobulinemia / Q000150:complications* / Q000175:diagnosis