title: Anthratectone and naphthotectone, two quinones from bioactive extracts of Tectona grandis.
abstract: Two new quinones, (an isoprenoid quinone, and a dimeric anthraquinone) named naphthotectone and anthratectone, respectively, were isolated from bioactive leaf extracts from Tectona grandis. Their structures were determined by a combination of 1D and 2D NMR techniques. The bioactivity profile of naphthotectone was assessed using the etiolated wheat coleoptiles bioassay in aqueous solutions at concentrations ranging from 10(-3) to 10(-5)M, as well as the standard target species lettuce, cress, tomato, and onion. Naphthotectone showed high level of activities in both bioassays. This fact, along with the presence of this compound as the major component in Tectona grandis, suggests that it may be involved in the allelopathic activity previously described for this species, and probably in other defense mechanisms.
authors.affiliation: Grupo de Alelopatía, Departamento de Química Orgánica, Facultad de Ciencias, Universidad de Cádiz, Campus de Excelencia Internacional Agroalimentario, ceiA3, C/ República Saharaui s/n, 11510, Puerto Real, Cádiz, Spain.
authors.forename: Rodney
authors.initials: R
authors.lastname: Lacret
authors.forename: Rosa M
authors.initials: RM
authors.lastname: Varela
authors.forename: José M G
authors.initials: JM
authors.lastname: Molinillo
authors.forename: Clara
authors.initials: C
authors.lastname: Nogueiras
authors.forename: Francisco A
authors.initials: FA
authors.lastname: Macías
mesh_terms: D001681:Biological Assay; D001688:Biological Products / Q000302:isolation & purification / Q000494:pharmacology; D003462:Cuba; D019686:Lamiaceae / Q000737:chemistry*; D019684:Magnoliopsida / Q000187:drug effects / Q000254:growth & development; D018515:Plant Leaves / Q000737:chemistry*; D011809:Quinones / Q000302:isolation & purification* / Q000494:pharmacology*; D013045:Species Specificity; D013055:Spectrophotometry, Infrared; D014908:Triticum / Q000187:drug effects / Q000254:growth & development
chemical_list: D001688:Biological Products; D011809:Quinones