title: Asymmetric substitutions of O-Boc-protected Morita-Baylis-Hillman adducts with pyrrole and indole derivatives.
abstract: An efficient asymmetric substitution process of O-Boc-protected Morita-Baylis-Hillman adducts with various pyrrole and indole derivatives has been developed in the presence of (DHQD)(2)PYR in THF, affording the corresponding products in good to high yields (up to 99% yield) and moderate to high ee values (up to 92 and 96% ee) under mild conditions.
authors.affiliation: Key Laboratory for Advanced Materials and Institute of Fine Chemicals, East China University of Science and Technology, 130 Mei Long Road, Shanghai, 200237, China.
authors.forename: Long
authors.initials: L
authors.lastname: Huang
authors.forename: Yin
authors.initials: Y
authors.lastname: Wei
authors.forename: Min
authors.initials: M
authors.lastname: Shi