title: [Comparative morphological study of thyroid gland in mammalian animals and man].
abstract: The objective of this study was to examine the morphological peculiarities of the thyroid gland in animals of different mammalian orders and in man at both macroscopic and microscopic level. 304 specimens of the thyroid gland obtained from the animals of 13 species and 5 mammalian orders and man, were studied. At the macroscopic level, the changes of lobar shape, presence and structural peculiarities of the isthmus, and its relative size were analyzed. At the microscopic level, the following parameters were determined in comparative aspect: the volume fractions of major structural components, the indices of activity, sclerosis and colloid accumulation, the standardized follicular profile shape and size, follicular epithelium height. With the increase of size of the species studied, a tendency was found for the increase of thyroid lobe width and the appearance of parenchymal isthmus, connecting the lobes. At the microscopic level, the variability of follicular profile shape and size was found to increase from small rodents to artiodactyls and man. According to morphological indices, the activity of the thyroid gland in artiodactyls and man was decreased as compared to that one in the other mammalian species.
authors.forename: V A
authors.initials: VA
authors.lastname: Zabrodin
authors.forename: E S
authors.initials: ES
authors.lastname: Tolstenkova
authors.forename: O A
authors.initials: OA
authors.lastname: Vasil'eva
mesh_terms: D000818:Animals; D004847:Epithelial Cells / Q000166:cytology* / Q000378:metabolism; D004848:Epithelium / Q000378:metabolism; D008322:Mammals / Q000033:anatomy & histology* / Q000378:metabolism; D013045:Species Specificity; D013961:Thyroid Gland / Q000166:cytology* / Q000378:metabolism