title: Extrapituitary production of anterior pituitary hormones: an overview.
abstract: Protein hormones from the anterior pituitary gland have well-established endocrine roles in their peripheral target glands. It is, however, now known that these proteins are also produced within many of their target tissues, in which they act as local autocrine or paracrine factors, with physiological and/or pathophysiological significance. This emerging concept is the focus of this brief review.
authors.affiliation: Department of Physiology, University of Alberta, Edmonton, AB, T6G 2H7, Canada, steve.harvey@ualberta.ca.
authors.forename: S
authors.initials: S
authors.lastname: Harvey
authors.forename: C
authors.initials: C
authors.lastname: Arámburo
authors.forename: E J
authors.initials: EJ
authors.lastname: Sanders
mesh_terms: D000818:Animals; D019898:Autocrine Communication / Q000502:physiology*; D001921:Brain / Q000378:metabolism; D041981:Gastrointestinal Tract / Q000378:metabolism; D006801:Humans; D008168:Lung / Q000378:metabolism; D019899:Paracrine Communication / Q000502:physiology*; D010908:Pituitary Hormones, Anterior / Q000378:metabolism*; D012867:Skin / Q000378:metabolism
chemical_list: D010908:Pituitary Hormones, Anterior