title: [Experience of proton stereotactic therapy for cerebral arteriovenous malformations in children].
abstract: The authors present the results of proton stereotactic therapy (using continuous double-axis pendulum irradiation) in 27 children with cerebral arteriovenous malformations (AVM). At the moment of therapy, the children's age was 6 to 15 years. The volume of AVM was 0.2 to 31.2 cm3. The absorbed doses in the maximum of a dose field were 40 to 80 Gy. Complete AVM obliteration (the mean volume in the group was 3.03 cm3) was obtained in 11 (41%) patients. A 50% or more reduction in AVM volume (mean volume, 10.6 cm3) was seen in 8 (30%) patients. There was a less than 50% reduction in AVM volumes (mean volume 9.6 cm3) in 2 (7%) patients and no effect could be achieved in 6 (22%) (mean AMV volume 19.7 cm3).
authors.forename: S V
authors.initials: SV
authors.lastname: Gerasimov
authors.forename: V M
authors.initials: VM
authors.lastname: Vinogradov
authors.forename: Iu A
authors.initials: IuA
authors.lastname: Garmashov
authors.forename: R A
authors.initials: RA
authors.lastname: Shalek
mesh_terms: D000293:Adolescent; D001921:Brain / Q000098:blood supply* / Q000503:physiopathology; D002533:Cerebral Angiography; D002648:Child; D004307:Dose-Response Relationship, Radiation; D004621:Embolization, Therapeutic / Q000379:methods; D005260:Female; D006801:Humans; D002538:Intracranial Arteriovenous Malformations / Q000150:complications / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*; D020300:Intracranial Hemorrhages / Q000209:etiology / Q000503:physiopathology / Q000517:prevention & control*; D008297:Male; D019060:Minimally Invasive Surgical Procedures / Q000379:methods; D011522:Protons; D016634:Radiosurgery / Q000379:methods*; D012720:Severity of Illness Index; D016896:Treatment Outcome
chemical_list: D011522:Protons