title: Travel-related disseminated Penicillium marneffei infection in a renal transplant patient.
abstract: Penicillium marneffei is a thermally dimorphic fungus that causes severe human immunodeficiency virus-related opportunistic infection in endemic areas of Southeast Asia and has rarely been reported in solid organ transplant (SOT) recipients. We report here the case of an Australian renal transplant patient who presented with disseminated P. marneffei infection shortly after a 10-day holiday to Vietnam, and review all previously published cases of penicilliosis associated with renal transplantation. This is the first reported case, to our knowledge, of P. marneffei infection in an SOT recipient acquired during travel to an endemic country, and highlights the importance of an accurate travel history when opportunistic infection is suspected, as well as giving appropriate health advice to transplant patients who travel.
authors.affiliation: Department of Infectious Diseases, Fremantle Hospital, Perth, Western Australia, Australia. julie.hart@health.wa.gov.au
authors.forename: J
authors.initials: J
authors.lastname: Hart
authors.forename: J R
authors.initials: JR
authors.lastname: Dyer
authors.forename: B M
authors.initials: BM
authors.lastname: Clark
authors.forename: D G
authors.initials: DG
authors.lastname: McLellan
authors.forename: S
authors.initials: S
authors.lastname: Perera
authors.forename: P
authors.initials: P
authors.lastname: Ferrari
mesh_terms: D000368:Aged; D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D001315:Australia; D006801:Humans; D016867:Immunocompromised Host; D017964:Itraconazole / Q000627:therapeutic use; D016030:Kidney Transplantation / Q000009:adverse effects*; D008297:Male; D009181:Mycoses / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D010407:Penicillium / Q000145:classification / Q000302:isolation & purification*; D014195:Travel; D016896:Treatment Outcome; D014744:Vietnam
chemical_list: D000935:Antifungal Agents; C068538:liposomal amphotericin B; D017964:Itraconazole; D000666:Amphotericin B