title: Stent thrombosis: understanding and managing a critical problem.
abstract: Coronary artery stent thrombosis (ST), defined as the thrombotic occlusion of a stented segment, is an infrequent but serious complication of percutaneous coronary intervention (PCI). The clinical consequences of ST are severe, because acute stent occlusion results in myocardial infarction and death in up to 45% of cases. Specific patient and procedural characteristics increase the risk of ST, but optimized interventional techniques and antiplatelet therapies have the potential to decrease ST and improve cardiovascular outcomes following PCI.
authors.affiliation: Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, 77 Avenue Louis Pasteur, NRB 742, Boston, MA, 02115, USA.
authors.forename: Julio F
authors.initials: JF
authors.lastname: Marchini
authors.forename: Andre
authors.initials: A
authors.lastname: Manica
authors.forename: Kevin
authors.initials: K
authors.lastname: Croce