title: Skin metastases in non-small cell lung cancer.
abstract: Skin metastasis associated with lung cancer is an uncommon manifestation and usually portends an aggressive clinical course. It can be either synchronous with the underlying malignancy or be the sign of recurrence. Solitary metastases can be treated with surgical resection or radiation therapy, but multiple lesions are usually treated with palliative chemotherapy. With standard platinum-based doublet regimens, treatment results are usually poor. With the advent of newer agents like pemetrexed, bevacizumab and erlotinib, perhaps results may improve with ongoing clinical trials.
authors.affiliation: Division of Hematology and Medical Oncology, Department of Internal Medicine, Ellis Fischel Cancer Center/University of Missouri School of Medicine, Columbia, MO 65203, USA.
authors.forename: Ravi K
authors.initials: RK
authors.lastname: Bobba
authors.forename: Jamie L
authors.initials: JL
authors.lastname: Odem
authors.forename: Donald C
authors.initials: DC
authors.lastname: Doll
authors.forename: Michael C
authors.initials: MC
authors.lastname: Perry
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use; D002289:Carcinoma, Non-Small-Cell Lung / Q000473:pathology*; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology*; D011379:Prognosis; D012878:Skin Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000556:secondary* / Q000628:therapy*
chemical_list: D000970:Antineoplastic Agents