title: Seroepidemiological study of Crimean-Congo haemorrhagic fever in Greece, 2009-2010.
abstract: To estimate endemic areas for Crimean-Congo haemorrhagic fever (CCHF) in Greece, a country-wide seroepidemiological study was conducted, and 1611 human sera were prospectively collected along with data regarding possible risk factors for acquisition of infection, and tested for CCHF virus IgG antibodies by ELISA. The overall seroprevalence was 4.2%, with significant differences among prefectures, ranging from 0 to 27.5%. Multivariate analysis revealed that slaughtering and agricultural activities were significant risk factors for CCHFV seropositivity. The significantly high seroprevalence in specific prefectures, together with the extremely low number of CCHF cases, suggest that this phenomenon might be strain-related.
authors.affiliation: First Department of Microbiology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.
authors.forename: P
authors.initials: P
authors.lastname: Sidira
authors.forename: H C
authors.initials: HC
authors.lastname: Maltezou
authors.forename: A-B
authors.initials: AB
authors.lastname: Haidich
authors.forename: A
authors.initials: A
authors.lastname: Papa
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000383:Agriculture; D000914:Antibodies, Viral / Q000097:blood*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005843:Geography; D006115:Greece / Q000453:epidemiology; D003225:Hemorrhagic Fever Virus, Crimean-Congo / Q000276:immunology*; D006479:Hemorrhagic Fever, Crimean / Q000453:epidemiology*; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D016036:Seroepidemiologic Studies
chemical_list: D000914:Antibodies, Viral; D007074:Immunoglobulin G