title: Multiple parallel-line endotheliitis--a form of herpes simplex keratitis?
abstract: OBJECTIVE
  To report a case of multiple parallel-line endotheliitis with a possible link to herpes simplex virus.
  
  
  METHODS
  An 89-year-old woman presented with new onset reduced vision in her left eye. Her visual acuity with pinhole was 20/120 with the affected eye and 20/30 in the right. She had a white left eye with significant corneal edema and keratic precipitates. These were arranged in a striking pattern of multiple parallel lines resembling railroad tracks. She responded very well to topical steroid and was found to have positive immunoglobulin G and immunoglobulin M titers for herpes simplex virus.
  
  
  CONCLUSIONS
  Multiple parallel-line endotheliitis may represent a mild expression of herpes simplex keratitis. It appears to be exquisitely sensitive to topical steroid on its own suggesting that immune response has a dominant role in its pathogenesis.
authors.affiliation: Department of Ophthalmology, St James' University Hospital, Leeds, UK.
authors.forename: Lucy A
authors.initials: LA
authors.lastname: Oxley
authors.forename: Zia I
authors.initials: ZI
authors.lastname: Carrim
mesh_terms: D000369:Aged, 80 and over; D000914:Antibodies, Viral / Q000032:analysis; D000998:Antiviral Agents / Q000008:administration & dosage / Q000627:therapeutic use; D003937:Diagnosis, Differential; D004728:Endothelium, Corneal / Q000473:pathology* / Q000821:virology; D005260:Female; D005500:Follow-Up Studies; D005938:Glucocorticoids / Q000008:administration & dosage; D018259:Herpesvirus 1, Human / Q000276:immunology*; D006801:Humans; D016849:Keratitis, Herpetic / Q000175:diagnosis* / Q000188:drug therapy / Q000821:virology; D009883:Ophthalmic Solutions; D014792:Visual Acuity
chemical_list: D000914:Antibodies, Viral; D000998:Antiviral Agents; D005938:Glucocorticoids; D009883:Ophthalmic Solutions