title: Delirium secondary to pregabalin.
abstract: Fibromyalgia is a common and disabling disease, and treatment can be challenging. More recently, pregabalin has been approved to treat pain associated with fibromyalgia. However, it can have serious neuropsychiatric sequelae. Several case reports have documented delirium secondary to pregabalin, usually in older patients with multiple medical comorbidities and concurrent medications. We describe a case of delirium in a young patient without significant medical problems and in the absence of other potentially causal medications. In this case, pregabalin appears to be the single causal etiology for delirium. We recommend clinicians to consider the causal role it may play in any patient who presents with delirium.
authors.affiliation: Memorial University of Newfoundland, Geriatric Psychiatry Day Hospital, St. John's, NL, Canada A1A 1E5. drcatherinehickey@gmail.com
authors.forename: Catherine
authors.initials: C
authors.lastname: Hickey
authors.forename: Barbara
authors.initials: B
authors.lastname: Thomas
mesh_terms: D000700:Analgesics / Q000008:administration & dosage / Q000009:adverse effects*; D003693:Delirium / Q000139:chemically induced* / Q000503:physiopathology; D005260:Female; D005356:Fibromyalgia / Q000188:drug therapy; D006801:Humans; D008875:Middle Aged; D000069583:Pregabalin; D016896:Treatment Outcome; D005680:gamma-Aminobutyric Acid / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives*
chemical_list: D000700:Analgesics; D000069583:Pregabalin; D005680:gamma-Aminobutyric Acid