title: Biotransformation of (1S)-2-carene and (1S)-3-carene by Picea abies suspension culture.
abstract: Biotransformation of (1S)-2-carene and (1S)-3-carene by Picea abies suspension culture led to the formation of oxygenated products. (1S)-2-Carene was transformed slowly and the final product was identified as (1S)-2-caren-4-one. On the other hand, the transformation of (1S)-3-carene was rapid and finally led to the formation of (1S)-3-caren-5-one and (1S)-2-caren-4-one as equally abundant major products. The time-course of the reaction indicates that some products abundant at the beginning of the reaction (e.g. (1S, 3S, 4R)-3,4-epoxycarane and (1R)-p-mentha-1(7),2-dien-8-ol) were consumed by a subsequent transformations. Thus, a precise selection of the biotransformation time may be used for a production of specific compounds.
authors.affiliation: Laboratory of Plant Biotechnologies, Joint Laboratory of Institute of Experimental Botany, Academy of Sciences of the Czech Republic, v.v.i., Rozvojova 263, 165 02 Prague 6, Czech Republic. dvorakova@ueb.cas.cz
authors.forename: Marcela
authors.initials: M
authors.lastname: Dvorakova
authors.forename: Irena
authors.initials: I
authors.lastname: Valterova
authors.forename: David
authors.initials: D
authors.lastname: Saman
authors.forename: Tomas
authors.initials: T
authors.lastname: Vanek
mesh_terms: D000081008:Bicyclic Monoterpenes; D001711:Biotransformation; D018929:Cell Culture Techniques / Q000379:methods*; D039821:Monoterpenes / Q000737:chemistry / Q000378:metabolism*; D010084:Oxidation-Reduction; D028222:Picea / Q000166:cytology* / Q000378:metabolism*; D013535:Suspensions; D013997:Time Factors
chemical_list: D000081008:Bicyclic Monoterpenes; D039821:Monoterpenes; D013535:Suspensions; C113988:2-carene; C030218:3-carene