title: [Interrelation of endothelial and myocardial dysfunction in persons of elderly age with arterial hypertension].
abstract: For the purpose of estimation of peculiarities of interrelation between endothelial dysfunction (ED) and myocardial dysfunction (MD) in elderly persons due to arterial hypertension (AH) 66 patients of elderly age with AH of II stage and 26 persons of similar age without cardiovascular diseases were examined. It is established, that development AH is accompanied by formation of a concentric hypertrophy and concentric remodelling of myocardium, diastolic and systolodiastolic myocardial dysfunction, its expressiveness is interfaced to severity of endothelial dysfunction. Progressing of ED is accompanied by infringements of lipids' metabolism, increasing of their peroxidation activity and decreasing in efficiency of anti-oxidation protection.
authors.forename: N K
authors.initials: NK
authors.lastname: Gorshunova
authors.forename: N V
authors.initials: NV
authors.lastname: Medvedev
authors.forename: D N
authors.initials: DN
authors.lastname: Ukraintseva
authors.forename: S S
authors.initials: SS
authors.lastname: Mauer
mesh_terms: D000367:Age Factors; D000368:Aged; D015415:Biomarkers; D015150:Echocardiography, Doppler; D004730:Endothelium, Vascular / Q000378:metabolism / Q000503:physiopathology; D006333:Heart Failure / Q000175:diagnosis / Q000378:metabolism / Q000503:physiopathology; D006801:Humans; D006973:Hypertension / Q000378:metabolism / Q000503:physiopathology; D050356:Lipid Metabolism; D015227:Lipid Peroxidation; D020097:Natriuretic Peptide, Brain / Q000378:metabolism; D018384:Oxidative Stress; D012307:Risk Factors; D012720:Severity of Illness Index; D020257:Ventricular Remodeling
chemical_list: D015415:Biomarkers; D020097:Natriuretic Peptide, Brain