title: Transmission of Guanarito and Pirital viruses among wild rodents, Venezuela.
abstract: Samples from rodents captured on a farm in Venezuela in February 1997 were tested for arenavirus, antibody against Guanarito virus (GTOV), and antibody against Pirital virus (PIRV). Thirty-one (48.4%) of 64 short-tailed cane mice (Zygodontomys brevicauda) were infected with GTOV, 1 Alston's cotton rat (Sigmodon alstoni) was infected with GTOV, and 36 (64.3%) of 56 other Alston's cotton rats were infected with PIRV. The results of analyses of field and laboratory data suggested that horizontal transmission is the dominant mode of GTOV transmission in Z. brevicauda mice and that vertical transmission is an important mode of PIRV transmission in S. alstoni rats. The results also suggested that bodily secretions and excretions from most GTOV-infected short-tailed cane mice and most PIRV-infected Alston's cotton rats may transmit the viruses to humans.
authors.affiliation: University of Texas Medical Branch, Galveston, Texas, USA.
authors.forename: Mary L
authors.initials: ML
authors.lastname: Milazzo
authors.forename: Maria N B
authors.initials: MN
authors.lastname: Cajimat
authors.forename: Gloria
authors.initials: G
authors.lastname: Duno
authors.forename: Freddy
authors.initials: F
authors.lastname: Duno
authors.forename: Antonio
authors.initials: A
authors.lastname: Utrera
authors.forename: Charles F
authors.initials: CF
authors.lastname: Fulhorst
mesh_terms: D000818:Animals; D000835:Animals, Wild / Q000821:virology; D000914:Antibodies, Viral / Q000097:blood; D001117:Arenaviridae Infections / Q000453:epidemiology / Q000635:transmission / Q000662:veterinary*; D018050:Arenavirus / Q000145:classification / Q000235:genetics / Q000276:immunology; D003411:Arvicolinae / Q000821:virology*; D021821:Communicable Diseases, Emerging / Q000453:epidemiology / Q000635:transmission / Q000662:veterinary; D005260:Female; D006801:Humans; D008297:Male; D010802:Phylogeny; D014687:Venezuela / Q000453:epidemiology; D017201:Virus Shedding; D015047:Zoonoses / Q000635:transmission
chemical_list: D000914:Antibodies, Viral