title: Ulcerative keratitis following particulate elemental gold deposition.
abstract: OBJECTIVE
  To describe a case of 68-year-old male industrial chemist who received a chemical injury after a gold/amine compound exploded causing bilateral eye injuries. No apparent long-term problems were anticipated. After cataract extraction 40 years later, he developed a localized ulcerative keratitis adjacent to embedded gold in the cornea.
  
  
  METHODS
  To describe the clinical features, management, and outcomes.
  
  
  RESULTS
  Successful treatment with topical hydrocortisone was achieved. Subsequently, 3 further episodes of ulcerative keratitis were treated with topical steroid therapy without need for systemic immunosuppression. A systemic vasculitic/autoimmune screen was normal.
  
  
  CONCLUSIONS
  Ocular chrysiasis is well recognized after systemic gold administration and is normally considered inert, but in this case exogenous gold deposition might have been a contributing factor to very localized and repeated episodes of stromal erosion in this man, many years after the original injury. To the best of our knowledge this is the first such reported case.
authors.affiliation: Birmingham and Midland Eye Centre, City Hospital, Birmingham, United Kingdom. akash.raj@nhs.net
authors.forename: Akash
authors.initials: A
authors.lastname: Raj
authors.forename: Geraint P
authors.initials: GP
authors.lastname: Williams
authors.forename: Nicholas R
authors.initials: NR
authors.lastname: Hawksworth
mesh_terms: D000062:Accidents, Occupational; D000368:Aged; D002386:Cataract / Q000628:therapy; D002617:Chemical Industry; D003315:Cornea / Q000187:drug effects / Q000601:surgery; D003320:Corneal Ulcer / Q000139:chemically induced* / Q000188:drug therapy*; D006046:Gold / Q000009:adverse effects*; D006801:Humans; D006854:Hydrocortisone / Q000627:therapeutic use; D008297:Male
chemical_list: D006046:Gold; D006854:Hydrocortisone