title: Novel picornavirus in domesticated common quail (Coturnix coturnix) in Hungary.
abstract: This study reports the detection of a novel picornavirus in domesticated common quail (Coturnix coturnix) in Hungary. The 8159-nucleotide (nt)-long RNA genome of this virus, named quail picornavirus (QPV1-HUN/2010; JN674502), shows only 43%, 39% and 47% amino acid (aa) identity in the P1 (857 aa), P2 (458 aa) and P3 (777 aa) coding regions respectively, to the closest reference, avian sapelovirus. The 5'UTR contains a variant type IV IRES with a 20-nt-long apical "8"-like structure that is conserved in avian-origin and seal picornaviruses. The 390-aa-long L protein is cysteine rich and encodes two copies of a 34-aa-long repeat motif. Quail picornavirus represents a novel picornavirus species and perhaps a novel genus.
authors.affiliation: Regional Laboratory of Virology, National Reference Laboratory of Gastroenteric Viruses, ÁNTSZ Regional Institute of State Public Health Service, Szabadság út 7, Pécs 7623, Hungary.
authors.forename: Péter
authors.initials: P
authors.lastname: Pankovics
authors.forename: Akos
authors.initials: A
authors.lastname: Boros
authors.forename: Gábor
authors.initials: G
authors.lastname: Reuter
mesh_terms: D020121:5' Untranslated Regions; D000818:Animals; D001483:Base Sequence; D001715:Bird Diseases / Q000821:virology*; D016000:Cluster Analysis; D003370:Coturnix / Q000821:virology*; D005838:Genotype; D006814:Hungary; D008958:Models, Molecular; D008969:Molecular Sequence Data; D009690:Nucleic Acid Conformation; D010802:Phylogeny; D010849:Picornaviridae / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification*; D010850:Picornaviridae Infections / Q000662:veterinary* / Q000821:virology; D012367:RNA, Viral / Q000235:genetics; D017422:Sequence Analysis, DNA; D017386:Sequence Homology, Amino Acid; D014764:Viral Proteins / Q000235:genetics
chemical_list: D020121:5' Untranslated Regions; D012367:RNA, Viral; D014764:Viral Proteins