title: Sulfadimethoxine and sulfaguanidine: their sorption potential on natural soils.
abstract: Sulfonamides (SAs) are one of the oldest groups of veterinary chemotherapeutic agents. As these compounds are not completely metabolized in animals, a high proportion of the native form is excreted in feces and urine. They are therefore released either directly to the environment in aquacultures and by grazing animals, or indirectly during the application of manure or slurry. Once released into the environment, SAs become distributed among various environmental compartments and may be transported to surface or ground waters. The physicochemical properties of SAs, dosage and nature of the matrix are the factors mainly responsible for their distribution in the natural environment. Although these rather polar compounds have been in use for over half a century, knowledge of their fate and behavior in soil ecosystems is still limited. Therefore, in this work we have determined the sorption potential of sulfadimethoxine and sulfaguanidine on various natural soils. The influence on sorption of external factors, such as ionic strength and pH, were also determined. The sorption coefficients (K(d)) obtained for the sulfonamides investigated were quite low (from 0.20 to 381.17 mL g(-1) for sulfadimethoxine and from 0.39 to 35.09 mL g(-1) for sulfaguanidine), which indicated that these substances are highly mobile and have the potential to run off into surface waters and/or infiltrate ground water. Moreover, the sorption of these pharmaceuticals was found to be influenced by OC, soil solution pH and ionic strength, with higher K(d) values for soils of higher OC and lower K(d) values with increasing pH and ionic strength.
authors.affiliation: Department of Environmental Analysis, University of Gdańsk, ul. Sobieskiego 18, 80-952 Gdańsk, Poland. abialk@chem.univ.gda.pl
authors.forename: Anna
authors.initials: A
authors.lastname: Białk-Bielińska
authors.forename: Joanna
authors.initials: J
authors.lastname: Maszkowska
authors.forename: Wojciech
authors.initials: W
authors.lastname: Mrozik
authors.forename: Agata
authors.initials: A
authors.lastname: Bielawska
authors.forename: Marta
authors.initials: M
authors.lastname: Kołodziejska
authors.forename: Richard
authors.initials: R
authors.lastname: Palavinskas
authors.forename: Piotr
authors.initials: P
authors.lastname: Stepnowski
authors.forename: Jolanta
authors.initials: J
authors.lastname: Kumirska
mesh_terms: D000327:Adsorption; D000890:Anti-Infective Agents / Q000032:analysis / Q000737:chemistry*; D008956:Models, Chemical; D012987:Soil / Q000737:chemistry*; D012989:Soil Pollutants / Q000032:analysis / Q000737:chemistry*; D013412:Sulfadimethoxine / Q000032:analysis / Q000737:chemistry*; D013414:Sulfaguanidine / Q000032:analysis / Q000737:chemistry*
chemical_list: D000890:Anti-Infective Agents; D012987:Soil; D012989:Soil Pollutants; D013414:Sulfaguanidine; D013412:Sulfadimethoxine