title: Preoperative evaluation of early colorectal cancer using an ultrasound mini probe.
abstract: OBJECTIVE
  We investigated whether endoscopic ultrasonography (EUS) can assess the depth of invasion of early colorectal cancer exhibiting the V pit pattern on magnifying endoscopy with submucosal invasion of 1,000 μm or deeper.
  
  
  METHODS
  Among 38 colorectal tumors exhibiting the V pit pattern on magnifying endoscopy, the findings on EUS with a mini-probe (15 MHz) were compared with histopathological findings. The diagnostic accuracy, sensitivity and specificity of EUS were examined separately in tumors exhibiting the Vi or V5 pit pattern.
  
  
  RESULTS
  Diagnostic accuracy of EUS for cancers exhibiting the Vi pit pattern on magnifying endoscopy with submucosal invasion of 1,000 μm or deeper was 9/15 (60%). Sensitivity was 90%, specificity 14.3%, positive predictive value 31.7% and negative predictive value 76.3%. Diagnostic accuracy of EUS for cancers exhibiting the VN pit pattern on magnify-ing endoscopy with submucosal invasion of 1,000 μm or deeper was 13/18 (72%). The sensitivity and specificity of EUS were 100% and 37.5%, respectively.
  
  
  CONCLUSIONS
  EUS tended to diagnose the invasion depth of cancer with submucosal invasion exhibiting the V pit pattern as deeper than it actually was. EUS accurately diagnosed early colorectal cancer with shallow invasion exhibiting the VN pit pattern and surgery was avoided.
authors.affiliation: Department of Gastroenterology and Hepatology, Yamaguchi University, Graduate School of Medicine, Yamaguchi, Japan.
authors.forename: Ryo
authors.initials: R
authors.lastname: Tanabe
authors.forename: Shingo
authors.initials: S
authors.lastname: Higaki
authors.forename: Toshikazu
authors.initials: T
authors.lastname: Gondo
authors.forename: Isao
authors.initials: I
authors.lastname: Sakaida
mesh_terms: D000236:Adenoma / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D016009:Chi-Square Distribution; D003082:Colectomy; D003113:Colonoscopy / Q000379:methods; D015179:Colorectal Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D055088:Early Detection of Cancer; D019160:Endosonography / Q000295:instrumentation*; D004867:Equipment Design; D006801:Humans; D007089:Image Enhancement; D007413:Intestinal Mucosa / Q000473:pathology; D007564:Japan; D008197:Lymph Node Excision; D008904:Miniaturization; D009361:Neoplasm Invasiveness; D011237:Predictive Value of Tests; D011300:Preoperative Care; D011379:Prognosis; D012680:Sensitivity and Specificity