title: Rhodium catalyzed C-H olefination of N-benzoylsulfonamides with internal alkenes.
abstract: An annulation via tandem rhodium catalyzed C-H olefination of N-benzoylsulfonamides with internal olefins followed by C-N bond formation is disclosed. A N-substituted quaternary center is formed during the reaction thus providing efficient access to a series of 3,3-disubstituted isoindolinones.
authors.affiliation: Department of Biochemistry, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, Texas 75390-9038, USA. chen.zhu@utsouthwestern.edu
authors.forename: Chen
authors.initials: C
authors.lastname: Zhu
authors.forename: John R
authors.initials: JR
authors.lastname: Falck
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D002384:Catalysis; D012238:Rhodium / Q000737:chemistry*; D013449:Sulfonamides / Q000737:chemistry*
chemical_list: D000475:Alkenes; D013449:Sulfonamides; D012238:Rhodium