title: Actual situation regarding cardiac etiology determined by clinical diagnosis of and medical examiner's postmortem findings on witnessed out-of-hospital cardiac arrest cases.
abstract: OBJECTIVE
  To examine indicators that may assist in the diagnosis of cardiac etiology using simple tests in witnessed cardiac etiology out-of-hospital cardiac arrest cases, which is emphasized in the Utstein Style.
  
  
  METHODS
  The subjects were 165 witnessed cardiac etiology out-of-hospital cardiac arrest cases, which were transported to Kobe University Hospital during the five-year period between January 1, 2005 and December 31, 2009. A comparative study was conducted into whether there were any significant differences in the initial electrocardiogram (ECG) and the various early diagnostic markers of acute myocardial infarction between the group who were finally diagnosed as being of cardiac etiology and the group who were finally diagnosed as being of non-cardiac etiology.
  
  
  RESULTS
  Of the 165 witnessed cardiac etiological cases, 69 cases were finally re-classified as non-cardiac etiological cases on the basis of scrutiny after admission or postmortem findings by the Medical Examiner. Ventricular fibrillation shown in the initial ECG and Qualitative cardiac troponin T test positive were significantly higher in the final diagnosis cardiac group than in the final diagnosis non-cardiac group. Ventricular fibrillation and troponin T positive can be seen as significant indicators in determining whether a case was cardiac or non-cardiac, and the model χ2 test result of p < 0.01 in the multiple logistic regression analysis was significant, and the determining predictive value was 65.4%.
  
  
  CONCLUSIONS
  The indicators which should be noted in simple tests to improve the precision of discrimination of cardiac etiology in out-of-hospital cardiac arrests are ventricular fibrillation in the initial ECG and the qualitative test of cardiac troponin T.
authors.affiliation: Division of Disaster and Emergency Medicine, Kobe University Graduate School of Medicine. takeyoshi4789@ybb.ne.jp
authors.forename: Takeshi
authors.initials: T
authors.lastname: Yoshida
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Nakao
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Itagaki
authors.forename: Takayuki
authors.initials: T
authors.lastname: Kato
authors.forename: Takahisa
authors.initials: T
authors.lastname: Kawashima
authors.forename: Noboru
authors.initials: N
authors.lastname: Ishii
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Nagasaki
authors.forename: Akira
authors.initials: A
authors.lastname: Imamura
mesh_terms: D001344:Autopsy; D003334:Coroners and Medical Examiners; D004562:Electrocardiography; D006801:Humans; D058687:Out-of-Hospital Cardiac Arrest / Q000175:diagnosis / Q000209:etiology*; D011237:Predictive Value of Tests; D012189:Retrospective Studies; D020107:Troponin T / Q000097:blood; D014693:Ventricular Fibrillation / Q000150:complications
chemical_list: D020107:Troponin T