title: Radiological correlate of ocular flutter in a case with paraneoplastic encephalitis.
abstract: We present an interesting [18F]fluoro-2-deoxyglucose positron emission tomography (FDG-PET) imaging finding in a patient with ocular flutter and cerebellar ataxia as part of anti-Ma 1/2 antibody-mediated paraneoplastic syndrome associated with a testicular seminoma. He had a typical anterior mesial temporal hyperintensity on magnetic resonance imaging (MRI) without gadolinium enhancement. In addition, his FDG-PET images showed increased deep cerebellar and inferior rectus and superior oblique ocular muscles FDG uptake. This case is the first to visualize in vivo the possible underlying neuropathological mechanism of ocular flutter associated with cerebellar nuclei on functional imaging.
authors.affiliation: Cleveland Clinic Foundation, Neurological Institute, Department of Neurology, Cleveland, OH 44195, USA. neweyc@ccf.org
authors.forename: Christopher R
authors.initials: CR
authors.lastname: Newey
authors.forename: Aarti
authors.initials: A
authors.lastname: Sarwal
authors.forename: Guiyun
authors.initials: G
authors.lastname: Wu
mesh_terms: D002524:Cerebellar Ataxia / Q000000981:diagnostic imaging*; D003937:Diagnosis, Differential; D004660:Encephalitis / Q000000981:diagnostic imaging*; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008297:Male; D008875:Middle Aged; D015835:Ocular Motility Disorders / Q000175:diagnosis; D020361:Paraneoplastic Syndromes, Nervous System / Q000000981:diagnostic imaging*; D059545:Paraneoplastic Syndromes, Ocular / Q000000981:diagnostic imaging*; D049268:Positron-Emission Tomography / Q000379:methods*; D019275:Radiopharmaceuticals; D013736:Testicular Neoplasms / Q000000981:diagnostic imaging*
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18