title: Has nanotechnology led to improved therapeutic outcomes?
abstract: Nanoparticulate drug delivery systems provide new opportunities for solving issues associated with problematic drugs or disease states and have, therefore, created great expectations in the field of drug delivery. This review focuses on the potential benefits of nanoparticles compared with other conventional delivery systems. Several nanoparticulate drug delivery systems have already been marketed or are currently under development and are presented in this review. Results from clinical trials demonstrate that nanoparticulate formulations generally enable superior therapeutic outcomes than compared with standard formulations. Therefore, the implementation of nanotechnology in drug delivery represents an important advance with substantial potential to improve therapeutic effectiveness and increase patient's quality of life.
authors.affiliation: Division of Pharmaceutics, The University of Texas at Austin, Austin, TX 78712, USA. sbosselmann@utexas.edu
authors.forename: Stephanie
authors.initials: S
authors.lastname: Bosselmann
authors.forename: Robert O
authors.initials: RO
authors.lastname: Williams
mesh_terms: D016503:Drug Delivery Systems / Q000379:methods*; D006801:Humans; D053758:Nanoparticles / Q000008:administration & dosage*; D036103:Nanotechnology / Q000379:methods*; D004364:Pharmaceutical Preparations / Q000008:administration & dosage*; D012995:Solubility
chemical_list: D004364:Pharmaceutical Preparations