title: Early experience in MRI-guided therapies of prostate cancer: HIFU, laser and photodynamic treatment.
abstract: Prostate cancer screening has resulted in earlier diagnosis with lower-grade disease, leading to over-detection and over-treatment in a significant number of patients. Current whole-gland radical treatments are associated with significant rates of morbidity. The high prevalence of low-risk disease together with an inability to accurately identify those men harboring more aggressive cancers has led to tremendous research in low-morbidity focal therapies for prostate cancer. This review summarizes the early experiences with focal therapy with emphasis on early applications of laser, high-intensity focuses ultrasound, and photodynamic approaches.
authors.affiliation: Department of Medical Imaging, University of Toronto, Toronto, ON, Canada.
authors.forename: M R
authors.initials: MR
authors.lastname: Da Rosa
authors.forename: J
authors.initials: J
authors.lastname: Trachtenberg
authors.forename: R
authors.initials: R
authors.lastname: Chopra
authors.forename: M A
authors.initials: MA
authors.lastname: Haider
mesh_terms: D006801:Humans; D053685:Laser Therapy; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D010778:Photochemotherapy; D011471:Prostatic Neoplasms / Q000628:therapy*; D036761:Ultrasound, High-Intensity Focused, Transrectal / Q000379:methods*