title: [Drug surveillance in hospitalized patients in miscellany ward at children's hospital].
abstract: BACKGROUND
  surveillance of the use of drugs after their commercialization is indispensable for detecting infrequent, but important, adverse effects. The objective was to evaluate adverse reactions and drug interactions detected during the treatment of the patients hospitalized in a pediatric hospital.
  
  
  METHODS
  a prospective study in the North Child Hospital "Juan de la Cruz Martínez Maceira," Santiago de Cuba, was carried out, applying the method of intensive surveillance of the hospitalized patients, adapted to our conditions, which were previous informed consent in a sample of 28 patients with different pathologies and pharmacological treatments. The data out was evaluated by Naranjo's algorithm, applying descriptive statistics.
  
  
  RESULTS
  ten adverse reactions and three drug interactions were detected after relating clinical and biosocial aspects with pharmacological analysis.
  
  
  CONCLUSIONS
  the method of intensive surveillance applied allowed us to identify the adverse reactions and the patients' drug interactions. The pharmacological measures proposals facilitated identifying the number of drug interactions which produce adverse reactions.
authors.affiliation: Centro de Toxicología y Biomedicina, Universidad de Ciencias Médicas, Santiago de Cuba, Cuba. olaysi@toxi.scu.sld.cu
authors.forename: Olaysi
authors.initials: O
authors.lastname: López-Rodríguez
authors.forename: Ineysi
authors.initials: I
authors.lastname: Pérez-Amaro
mesh_terms: D002648:Child; D004347:Drug Interactions; D064420:Drug-Related Side Effects and Adverse Reactions / Q000453:epidemiology*; D005260:Female; D006776:Hospitals, Pediatric; D006801:Humans; D008297:Male; D011446:Prospective Studies; D017751:Safety Management