title: Facial telangiectasia: an unusual manifestation of neonatal lupus erythematosus.
abstract: Neonatal lupus erythematosus (NLE) is an uncommon condition usually associated with maternal anti-Ro autoantibodies. The cutaneous lesions of NLE are usually transient, disappearing about six months after birth, but telangiectasia is a rare complication of NLE which persists. Telangiectasias are small focal red macules and papules created by abnormally prominent capillaries, venules, and arterioles and are a characteristic marker of connective tissue diseases. We report the case of an infant diagnosed with NLE presenting typical annular lesions, positive ANA and positive anti-Ro antibodies. By five months of age, both ANA and anti-Ro antibodies were negative and the annular cutaneous lesions had gradually faded, but small scattered focal red macules appeared on the face, especially in the peri-orbital area and scalp. The cutaneous lupus disappeared but the telangiectasia persisted. We would like to suggest that the diagnosis of NLE should be considered when cutaneous telangiectasias are observed in infants.
authors.affiliation: Department of Paediatric Dermatology, Hospital Sant Joan de Déu, Universitat de Barcelona, Barcelona Spain. rosa_guinovart@hotmail.com
authors.forename: R M
authors.initials: RM
authors.lastname: Guinovart
authors.forename: A
authors.initials: A
authors.lastname: Vicente
authors.forename: C
authors.initials: C
authors.lastname: Rovira
authors.forename: M
authors.initials: M
authors.lastname: Suñol
authors.forename: M A
authors.initials: MA
authors.lastname: González-Enseñat
mesh_terms: D000974:Antibodies, Antinuclear / Q000276:immunology*; D005145:Face; D005260:Female; D006801:Humans; D007223:Infant; D008180:Lupus Erythematosus, Systemic / Q000150:complications / Q000151:congenital* / Q000175:diagnosis / Q000276:immunology; D013684:Telangiectasis / Q000209:etiology*
chemical_list: D000974:Antibodies, Antinuclear; C035356:SS-A antibodies