title: N-acyl-N-carboxymethyl-2-nitroaniline and its analogues: a new class of water-soluble photolabile precursor of carboxylic acids.
abstract: The synthesis and photochemistry of a new class of water-soluble, photolabile protecting group, the N-carboxymethyl-2-nitroanilinyl (CNA) group, are described. All three CNA-caging compounds synthesized underwent clean photochemical reaction in aqueous buffer solution to produce the intended product of acetic acid, along with the corresponding nitroso aromatic.
authors.affiliation: Graduate School of Pure and Applied Sciences, University of Tsukuba, Tsukuba, Ibaraki, Japan.
authors.forename: Takuya
authors.initials: T
authors.lastname: Honda
authors.forename: Atsuya
authors.initials: A
authors.lastname: Momotake
authors.forename: Tatsuo
authors.initials: T
authors.lastname: Arai
mesh_terms: D000814:Aniline Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D002264:Carboxylic Acids / Q000737:chemistry*; D015394:Molecular Structure; D010782:Photolysis; D012995:Solubility; D014867:Water / Q000737:chemistry*
chemical_list: D000814:Aniline Compounds; D002264:Carboxylic Acids; D014867:Water