title: Laparoscopic total colectomy: Does the indication influence the outcome?
abstract: OBJECTIVE
  To assess and compare outcomes of laparoscopic total colectomy performed for a variety of indications.
  
  
  METHODS
  Sixty six patients underwent laparoscopic total colectomy for inflammatory bowel disease (IBD) (13) and other diseases (53). Data on demographics, pre- and post-operative outcomes were collected prospectively.
  
  
  RESULTS
  Mean operative time was 4.5 h. Conversion rate was 13.6%. Total colectomy performed for IBD was associated with a significantly higher anastomotic leak rate (23.1% vs 1.9%, P < 0.05). On univariate analysis, hand sewn anastomosis and treatment with more than 20 mg of prednisolone for at least 3 mo was associated with a higher anastomotic leak rate (P < 0.05). No significant difference was found in return of gut function and overall morbidity between disease groups.
  
  
  CONCLUSIONS
  Laparoscopic total colectomy is feasible and outcomes are equivalent whatever the indication, except for anastomotic leak rate which is higher for patients with IBD.
authors.affiliation: Eddy Cotte, Yves François, Olivier Glehen, Department of Digestive Surgery, Centre Hospitalo-Universitaire Lyon Sud, Hospices Civils de Lyon, 69495 Pierre Bénite Cedex, France.
authors.forename: Eddy
authors.initials: E
authors.lastname: Cotte
authors.forename: Faheez
authors.initials: F
authors.lastname: Mohamed
authors.forename: Stéphane
authors.initials: S
authors.lastname: Nancey
authors.forename: Yves
authors.initials: Y
authors.lastname: François
authors.forename: Olivier
authors.initials: O
authors.lastname: Glehen
authors.forename: Bernard
authors.initials: B
authors.lastname: Flourié
authors.forename: Jean-Christophe
authors.initials: JC
authors.lastname: Saurin
authors.forename: Gilles
authors.initials: G
authors.lastname: Poncet