title: Long-term outcomes of domestic hunan aqueous drainage implantation in refractory glaucoma.
abstract: OBJECTIVE
  To evaluate the long-term outcomes of a non-valved, Chinese-made Hunan aqueous drainage device (HAD) in patients with refractory glaucoma, compared to trabeculectomy.
  
  
  METHODS
  This was a retrospective observational case series, including 27 patients with refractory glaucoma who either underwent HAD implantation (n=11) or trabeculectomy (n=16). The mean follow-up was 27.9±13.5 (mean±SD) months. Intraocular pressure (IOP), visual acuity and postoperative complications were measured.
  
  
  RESULTS
  IOP was significantly lower at the last follow-up in both two groups compared with the baseline IOP (HAD: 58.4 to 10.0 mmHg, P>0.001; trabeculectomy:58.4 to 23.7 mmHg, P<0.001). One week, 1 month and 1 year after the operation, the average IOP of the HAD group was significantly lower than that of trabeculectomy group (P<0.05 at all time points). However, , the IOP did not differ significantly between the two groups at the time of last follow-up.
  
  
  CONCLUSIONS
  HAD implantation serves as a good option to control IOP in refractory glaucoma.
authors.affiliation: Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou, China. yangyangfan23@126.com
authors.forename: Yangfan
authors.initials: Y
authors.lastname: Yang
authors.forename: Xiahong
authors.initials: X
authors.lastname: Wang
authors.forename: Minshi
authors.initials: M
authors.lastname: Pi
mesh_terms: D005260:Female; D005500:Follow-Up Studies; D005901:Glaucoma / Q000601:surgery*; D020327:Glaucoma Drainage Implants; D006801:Humans; D007429:Intraocular Pressure; D008297:Male; D011183:Postoperative Complications / Q000175:diagnosis; D012189:Retrospective Studies; D014065:Tonometry, Ocular; D014130:Trabeculectomy; D016896:Treatment Outcome; D014792:Visual Acuity