title: [Surgical treatment of relapsing metastatic stromal tumor of the gastrointestinal tract].
abstract: The study included 63 patients with relapsing metastatic stromal tumor of the gastrointestinal tract (surgery - 34, tyrosinkinase inhibitors - 29). Cytoreductive surgery is indicated in patients showing positive response to target therapy. The highest survival rates were reported in cases of surgical treatment received in conjunction with pre- and postoperative therapy with tyrosinkinase inhibitors.
authors.forename: I S
authors.initials: IS
authors.lastname: Stilidi
authors.forename: P P
authors.initials: PP
authors.lastname: Arkhiri
authors.forename: M P
authors.initials: MP
authors.lastname: Nikulin
mesh_terms: D000328:Adult; D000368:Aged; D000465:Algorithms; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D017024:Chemotherapy, Adjuvant; D005260:Female; D046152:Gastrointestinal Stromal Tumors / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery*; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D020360:Neoadjuvant Therapy / Q000379:methods; D009364:Neoplasm Recurrence, Local / Q000473:pathology / Q000601:surgery; D009367:Neoplasm Staging; D047428:Protein Kinase Inhibitors / Q000627:therapeutic use*; D011505:Protein-Tyrosine Kinases / Q000037:antagonists & inhibitors*; D016019:Survival Analysis; D016896:Treatment Outcome
chemical_list: D000970:Antineoplastic Agents; D047428:Protein Kinase Inhibitors; D011505:Protein-Tyrosine Kinases