title: Urinary tract infection in patients with diabetes mellitus.
abstract: Urinary tract infection occurs with increased frequency and severity in patients with diabetes mellitus. General host factors enhancing risk for urinary tract infection in diabetics include age, metabolic control, and long term complications, primarily diabetic nephropathy and cystopathy. Alterations in the innate immune system have been described and may also contribute. Treatment of asymptomatic bacteriuria in diabetic patients is not indicated. Early diagnosis and prompt intervention is recommended to limit morbidity of symptomatic infection. Clinical studies comparing management of urinary tract infection in persons with diabetes compared to those without as well as diabetic patients with good or poor glucose control will be necessary to improve care of urinary infection in persons with diabetes mellitus.
authors.affiliation: Department of Internal Medicine, Sophien- und Hufeland-Klinikum Weimar, Germany. innere1@klinikum-weimar.de
authors.forename: Reinhard
authors.initials: R
authors.lastname: Fünfstück
authors.forename: Lindsay E
authors.initials: LE
authors.lastname: Nicolle
authors.forename: Markolf
authors.initials: M
authors.lastname: Hanefeld
authors.forename: Kurt G
authors.initials: KG
authors.lastname: Naber
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D058070:Asymptomatic Diseases / Q000453:epidemiology; D015331:Cohort Studies; D048909:Diabetes Complications / Q000453:epidemiology / Q000382:microbiology; D003922:Diabetes Mellitus, Type 1 / Q000453:epidemiology*; D003924:Diabetes Mellitus, Type 2 / Q000453:epidemiology*; D004927:Escherichia coli Infections / Q000188:drug therapy / Q000453:epidemiology*; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D012189:Retrospective Studies; D012307:Risk Factors; D014552:Urinary Tract Infections / Q000188:drug therapy / Q000453:epidemiology*
chemical_list: D000900:Anti-Bacterial Agents