title: Small randomized trial among low-birth-weight children receiving bacillus Calmette-Guérin vaccination at first health center contact.
abstract: A total of 105 low-birth-weight children presenting for first vaccination were randomized to receive bacillus Calmette-Guérin (BCG) immediately or later (current practice). The mortality rate ratio for BCG was 0.17 (95% CI = 0.02-1.35) within 3 days of enrollment, 0.28 (0.06-1.37) in the first month, and 0.27 (0.07-0.98) after 2 months of age. The mortality rate ratio was 0.41 (0.14-1.18) (P = 0.098) in infancy. Administration of BCG vaccine at first contact may contribute to lower mortality.
authors.affiliation: Bandim Health Project, Indepth Network, Bissau, Guinea-Bissau. S.biering@bandim.org
authors.forename: Sofie
authors.initials: S
authors.lastname: Biering-Sørensen
authors.forename: Peter
authors.initials: P
authors.lastname: Aaby
authors.forename: Bitiguida Mutna
authors.initials: BM
authors.lastname: Napirna
authors.forename: Adam
authors.initials: A
authors.lastname: Roth
authors.forename: Henrik
authors.initials: H
authors.lastname: Ravn
authors.forename: Amabelia
authors.initials: A
authors.lastname: Rodrigues
authors.forename: Hilton
authors.initials: H
authors.lastname: Whittle
authors.forename: Christine Stabell
authors.initials: CS
authors.lastname: Benn
mesh_terms: D001500:BCG Vaccine / Q000008:administration & dosage* / Q000276:immunology*; D005260:Female; D006801:Humans; D007223:Infant; D007226:Infant Mortality; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D008297:Male; D014611:Vaccination / Q000379:methods*
chemical_list: D001500:BCG Vaccine