title: [A case of local-recurring breast cancer under long term-treatment by capecitabine].
abstract: A 57-year-old woman had undergone a modified radical mastectomy at another medical institute. Six years after the resection, a tumor was confirmed and diagnosed as a recurrent metastasis in the right margin of the breastbone. The patient underwent chemoradiation therapy at the other medical institute and was then transferred to our institute, where treatment was continued. Four years after the recurrence, chemotherapy with capecitabine was started. Over the past 6 years, the capecitabine dose has not been changed and no signs of local recurrence have been seen. The values of biomarkers are normal. No adverse events, such as hand-foot syndrome, have occurred. Early during the capecitabine treatment, grade 2 elevations in the patient's GOT and GPT values were observed. However, these values recovered immediately without supportive therapy. At present, this patient is continuing to receive capecitabine treatment without experiencing any serious adverse events.
authors.affiliation: Dept. of Surgery, Yamato Municipal Hospital.
authors.forename: Kimiyasu
authors.initials: K
authors.lastname: Yoneyama
authors.forename: Toshio
authors.initials: T
authors.lastname: Takeshita
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Suzuki
authors.forename: Masaki
authors.initials: M
authors.lastname: Morise
authors.forename: Tetsutarou
authors.initials: T
authors.lastname: Suzuki
authors.forename: Shinya
authors.initials: S
authors.lastname: Kishi
authors.forename: Atsuko
authors.initials: A
authors.lastname: Tsutsui
authors.forename: Akiko
authors.initials: A
authors.lastname: Matsumoto
mesh_terms: D000964:Antimetabolites, Antineoplastic / Q000627:therapeutic use*; D001943:Breast Neoplasms / Q000188:drug therapy* / Q000473:pathology; D000069287:Capecitabine; D003841:Deoxycytidine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D005260:Female; D005472:Fluorouracil / Q000031:analogs & derivatives* / Q000627:therapeutic use; D006801:Humans; D008875:Middle Aged; D013997:Time Factors; D014057:Tomography, X-Ray Computed
chemical_list: D000964:Antimetabolites, Antineoplastic; D003841:Deoxycytidine; D000069287:Capecitabine; D005472:Fluorouracil