title: Myxolipoma in the tongue - a clinical case report and review of the literature.
abstract: In this article, we present our experience with a case of myxolipoma of the tongue. Lipoma is a mesenchymal benign tumor occurring with relatively high frequency. However, myxolipoma, one of the histological variant of lipoma characterized by mature adipose tissue and abundant mucoid substances, in the oral cavity is quite rare. The patient was a 52-year-old man who noticed a painless mass on the left border of tongue about 2 years ago. The lesion was noted at a complete medical checkup, and the patient was admitted to our institution for detailed examination. The mass was a palpable, soft and elastic nodule, 15 mm in diameter, covered with normal mucosa in the left inferior aspect of the tongue. The border of the tumor was well-defined, and computed tomography (CT) revealed a fat density within the mass. On the basis of these finding, the tumor was clinically diagnosed as lipoma and was excised under general anesthesia. Histopathologically, the tumor was a well-defined lobulated mass surrounded by a thin fibrous capsule within the muscle of the tongue. The tumor was diagnosed as myxolipoma because it was consisted of solid proliferation of mature adipocytes replaced by abundant mucoid substances. The post operative course was uneventful, and there was no evidence of recurrence 4 years after surgery.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Division of Cervico-Gnathostomatology, Graduate School of Biomedical Sciences, Hiroshima University, Japan.
authors.forename: Shigehiro
authors.initials: S
authors.lastname: Ono
authors.affiliation: Department of Cranio-Maxillo-Facial Surgery, Hannover Medical School, Germany.
authors.forename: Majeed
authors.initials: M
authors.lastname: Rana
authors.affiliation: Department of Oral and Maxillofacial Surgery, Division of Cervico-Gnathostomatology, Graduate School of Biomedical Sciences, Hiroshima University, Japan.
authors.forename: Masaaki
authors.initials: M
authors.lastname: Takechi
authors.affiliation: Center of Oral Clinical Examination, Hiroshima University Hospital, Kasumi 1-2-3, Minami-ku, Hiroshima, Japan.
authors.forename: Ikuko
authors.initials: I
authors.lastname: Ogawa
authors.affiliation: Department of Oral and Maxillofacial Surgery, Division of Cervico-Gnathostomatology, Graduate School of Biomedical Sciences, Hiroshima University, Japan.
authors.forename: Gaku
authors.initials: G
authors.lastname: Okui
authors.affiliation: Department of Oral and Maxillofacial Surgery, Division of Cervico-Gnathostomatology, Graduate School of Biomedical Sciences, Hiroshima University, Japan.
authors.forename: Yoshitsugu
authors.initials: Y
authors.lastname: Mitani
authors.affiliation: Department of Cranio-Maxillo-Facial Surgery, Hannover Medical School, Germany.
authors.forename: Nils-Claudius
authors.initials: NC
authors.lastname: Gellrich
authors.affiliation: Department of Oral and Maxillofacial Surgery, Division of Cervico-Gnathostomatology, Graduate School of Biomedical Sciences, Hiroshima University, Japan.
authors.forename: Nobuyuki
authors.initials: N
authors.lastname: Kamata
mesh_terms: D006801:Humans; D008067:Lipoma / Q000473:pathology* / Q000628:therapy*; D018208:Liposarcoma, Myxoid / Q000473:pathology* / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D014062:Tongue Neoplasms / Q000473:pathology* / Q000628:therapy*