title: Long-term survival following resection of brain metastases from pancreatic cancer.
abstract: Brain metastases originating from pancreatic cancer are associated with a dismal prognosis and, generally, therapeutic options remain palliative. We present the cases of two patients that developed brain metastases after resection of a pancreatic ductal adenocarcinoma. Brain metastases were resected successfully and neither patients developed any further tumor recurrence. These cases demonstrate that resection of brain metastatic lesions originating from pancreatic ductal adenocarcinoma is a reasonable therapeutic option with a chance for complete cure in some cases.
authors.affiliation: Clinic of General, Visceral and Transplantation Surgery, Ulm University Hospital, Steinhövelstr. 9, D-89075 Ulm, Germany.
authors.forename: Johannes
authors.initials: J
authors.lastname: Lemke
authors.forename: Thomas F E
authors.initials: TF
authors.lastname: Barth
authors.forename: Markus
authors.initials: M
authors.lastname: Juchems
authors.forename: Thomas
authors.initials: T
authors.lastname: Kapapa
authors.forename: Doris
authors.initials: D
authors.lastname: Henne-Bruns
authors.forename: Marko
authors.initials: M
authors.lastname: Kornmann
mesh_terms: D000368:Aged; D001932:Brain Neoplasms / Q000401:mortality* / Q000556:secondary*; D021441:Carcinoma, Pancreatic Ductal / Q000401:mortality / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D010190:Pancreatic Neoplasms / Q000401:mortality* / Q000473:pathology* / Q000601:surgery; D011379:Prognosis; D012008:Recurrence; D013997:Time Factors; D014057:Tomography, X-Ray Computed / Q000379:methods