title: Primitive cerebral melanoma: a diagnostic and management challenge. About 2 cases.
abstract: In this report of two cases of solitary cerebral meningeal melanoma, a rare tumor that presents both diagnostic and management challenges, the diagnosis of these lesions was based on a solitary leptomeningeal mass on MRI, a high mitotic rate on histology and the absence of extracerebral localizations. Although the radiological patterns can mimic those of other melanocytic tumors, MRI is a useful diagnostic tool for narrowing the differential diagnosis. Surgical removal remains the only effective treatment of these lesions, and can lead to prolonged survival in a few cases.
authors.affiliation: Department of radiology, Pasteur hospital, 30, avenue de la Voie-Romaine, CHU de Nice, 06000 Nice, France. mondot.l@chu-nice.fr
authors.forename: L
authors.initials: L
authors.lastname: Mondot
authors.forename: F
authors.initials: F
authors.lastname: Almairac
authors.forename: F
authors.initials: F
authors.lastname: Vandenbos
authors.forename: D
authors.initials: D
authors.lastname: Fontaine
authors.forename: M
authors.initials: M
authors.lastname: Frenay
authors.forename: S
authors.initials: S
authors.lastname: Chanalet
mesh_terms: D000368:Aged; D001932:Brain Neoplasms / Q000175:diagnosis* / Q000628:therapy*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008545:Melanoma / Q000175:diagnosis* / Q000628:therapy*; D016896:Treatment Outcome