title: Alkene metathesis approach to β-unsubstituted anti-allylic alcohols and their use in ene-yne metathesis.
abstract: The synthesis of β-unsubstituted, anti-allylic alcohols using a catalytic Evans aldol reaction conjoined with a relay-type ring-closing alkene metathesis is reported. The metathesis step serves to remove a β-alkenyl group, which facilitated the aldol step. The β-substituted enals serve as acrolein surrogates. The products were employed in ene-yne cross metathesis.
authors.affiliation: Department of Chemistry, University at Buffalo, the State University of New York, Buffalo, New York 14260, USA.
authors.forename: Joseph R
authors.initials: JR
authors.lastname: Clark
authors.forename: Jonathan M
authors.initials: JM
authors.lastname: French
authors.forename: Steven T
authors.initials: ST
authors.lastname: Diver