title: Entropic attraction of adhesion bonds toward cell boundaries.
abstract: Adhesion bonds between membranes and surfaces are attracted to each other via effective interactions whose origin is the entropy loss due to the reduction in the amplitude of the membrane thermal fluctuations in the vicinity of the adhesion bonds. These fluctuation-induced interactions are also expected to drive the adhesion bonds toward the rim of the cell as well as toward the surfaces of membrane inclusions. In this paper we analyze the attraction of adhesion bonds to the cell inner and outer boundaries. Our analysis shows that the probability distribution function of a single (diffusing) adhesion bond decays algebraically with the distance from the boundaries. Upon increasing the concentration of the adhesion bonds, the attraction to the boundaries becomes strongly self-screened.
authors.affiliation: Department of Biomedical Engineering, Ben Gurion University of the Negev, Be'er Sheva 84105, Israel.
authors.forename: Noam
authors.initials: N
authors.lastname: Weil
authors.forename: Oded
authors.initials: O
authors.lastname: Farago
mesh_terms: D002448:Cell Adhesion; D002462:Cell Membrane / Q000378:metabolism*; D019277:Entropy; D008565:Membrane Proteins / Q000378:metabolism; D008954:Models, Biological; D013696:Temperature
chemical_list: D008565:Membrane Proteins