title: Performance of a New HPV Cervi-Collect Collection and Transportation Kit.
abstract: Background. Liquid-based Pap (L-Pap) media are used for Pap and human papillomavirus (HPV) testing. Objectives. To compare RealTime High Risk (HR) HPV testing of a new collection kit (Cervi-Collect) and PreservCyt L-Pap specimens. To determine ease of use and safety of Cervi-Collect. Methods. L-Pap samples (n = 203) were tested with HC2 and RealTime HR HPV and Cervi-Collect with RealTime HR HPV. Discordant samples were genotyped. Results. L-Pap and Cervi-Collect specimens tested by RealTime HR HPV showed 93.1% agreement (Kappa 0.86). RealTime HR HPV and HC2 on L-Pap had 90.3% agreement (Kappa 0.80). RealTime HR HPV on Cervi-Collect and HC2 on L-Pap showed 88.2% agreement (Kappa 0.76). Sixteen of 21 samples which were HC2 negative and RealTime HR HPV positive on L-Pap or Cervi-Collect contained HR HPV genotypes. Eleven healthcare collectors were in strong agreement on a usability and safety questionnaire. Conclusion. Cervi-Collect samples were easy to collect and showed strong agreement with L-Pap samples tested with RealTime HR HPV or HC2.
authors.affiliation: St. Joseph's Healthcare Hamilton, McMaster University, Hamilton, ON, Canada L8N 4A6.
authors.forename: M
authors.initials: M
authors.lastname: Chernesky
authors.forename: S
authors.initials: S
authors.lastname: Huang
authors.forename: D
authors.initials: D
authors.lastname: Jang
authors.forename: B
authors.initials: B
authors.lastname: Erickson
authors.forename: J
authors.initials: J
authors.lastname: Salituro
authors.forename: H
authors.initials: H
authors.lastname: Engel
authors.forename: J
authors.initials: J
authors.lastname: Gilchrist
authors.forename: P
authors.initials: P
authors.lastname: Neuscheler
authors.forename: W B
authors.initials: WB
authors.lastname: Mak
authors.forename: K
authors.initials: K
authors.lastname: Abravaya