title: A case of primary cutaneous extranodal natural killer/t-cell lymphoma, nasal type, with a 22-year indolent clinical course.
abstract: Extranodal natural killer (NK)/T-cell lymphoma, nasal type, is a rare type of cytotoxic lymphoma involving mainly the upper aerodigestive tract and associated with Epstein-Barr virus. The disease has usually a poor prognosis related to several factors. The skin is the second most common affected organ, and cases may be localized to the skin only without any other extracutaneous manifestations. Although primary cutaneous cases may have a better prognosis, survival usually is still poor. We report a case of primary cutaneous extranodal NK/T-cell lymphoma, nasal type, in a 77-year-old woman with an indolent course for more than 22 years and still limited to the skin.
authors.affiliation: Research Unit of Dermatopathology, Department of Dermatology, Medical University of Graz, Auenbruggerplatz 8, Graz, Austria.
authors.forename: Daniel
authors.initials: D
authors.lastname: Zuriel
authors.forename: Regina
authors.initials: R
authors.lastname: Fink-Puches
authors.forename: Lorenzo
authors.initials: L
authors.lastname: Cerroni
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D054391:Lymphoma, Extranodal NK-T-Cell / Q000378:metabolism / Q000473:pathology* / Q000628:therapy; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000378:metabolism / Q000473:pathology / Q000628:therapy; D011878:Radiotherapy; D012878:Skin Neoplasms / Q000378:metabolism / Q000473:pathology* / Q000628:therapy