title: Hand, foot and mouth disease in Yunnan Province, China, 2008-2010.
abstract: This study was done to assess the epidemic features of hand, foot and mouth disease in Yunnan Province. Surveillance data from the beginning of 2008 through the end of 2010 were analyzed to conduct the demographic data of patients and morbidity as well as the estimation between possible risk factors for severe or fatal cases. Of the 75109 cases reported, laboratory tests confirmed 3691 cases. Thus, the average annual incidence proportion was 55 per 100000 population with a total case fatality rate of 0.04%. A seasonal peak was observed in May, along with a smaller winter peak in 2010. Most severe and fatal cases were caused by enterovirus 71. It is demonstrated that most of the severe and fatal cases occurred in very young children and that delayed access to health care led to the higher likelihood of serious illness.
authors.affiliation: Yunnan Provincial Centers for Disease Control and Prevention, Kunming, Yunnan, People's Republic of China.
authors.forename: Wen
authors.initials: W
authors.lastname: Xu
authors.affiliation: Yunnan Provincial Centers for Disease Control and Prevention, Kunming, Yunnan, People's Republic of China Ministry of Public Health, Nonthaburi, Thailand gzynjl@hotmail.com.
authors.forename: Li
authors.initials: L
authors.lastname: Jiang
authors.affiliation: Ministry of Public Health, Nonthaburi, Thailand.
authors.forename: Panithee
authors.initials: P
authors.lastname: Thammawijaya
authors.affiliation: Southeast Asia Regional Office, US Centers for Disease Control and Prevention, Bangkok, Thailand.
authors.forename: Somsak
authors.initials: S
authors.lastname: Thamthitiwat
mesh_terms: D002648:Child; D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D058872:Epidemics; D005260:Female; D006232:Hand, Foot and Mouth Disease / Q000453:epidemiology*; D006801:Humans; D015994:Incidence; D007223:Infant; D008297:Male; D012307:Risk Factors; D012621:Seasons