title: Sequential continuous flow processes for the oxidation of amines and azides by using HOF·MeCN.
abstract: The generation and use of the highly potent oxidising agent HOF·MeCN in a controlled single continuous flow process is described. Oxidations of amines and azides to corresponding nitrated systems by using fluorine gas, water and acetonitrile by sequential gas-liquid/liquid-liquid continuous flow procedures are reported.
authors.affiliation: Department of Chemistry, Durham University, Durham, United Kingdom.
authors.forename: Christopher B
authors.initials: CB
authors.lastname: McPake
authors.forename: Christopher B
authors.initials: CB
authors.lastname: Murray
authors.forename: Graham
authors.initials: G
authors.lastname: Sandford
mesh_terms: D000097:Acetonitriles / Q000737:chemistry*; D000148:Acids, Noncarboxylic / Q000737:chemistry*; D000588:Amines / Q000737:chemistry*; D002621:Chemistry / Q000295:instrumentation*; D017611:Fluorine Compounds / Q000737:chemistry*; D009574:Nitro Compounds / Q000737:chemistry; D010084:Oxidation-Reduction; D010087:Oxides / Q000737:chemistry*; D013997:Time Factors
chemical_list: D000097:Acetonitriles; D000148:Acids, Noncarboxylic; D000588:Amines; D017611:Fluorine Compounds; D009574:Nitro Compounds; D010087:Oxides; C032159:acetonitrile