title: Ray-tracing optical modeling of negative dysphotopsia.
abstract: Negative dysphotopsia is a relatively common photic phenomenon that may occur after implantation of an intraocular lens. The etiology of negative dysphotopsia is not fully understood. In this investigation, optical modeling was developed using nonsequential-component Zemax ray-tracing technology to simulate photic phenomena experienced by the human eye. The simulation investigated the effects of pupil size, capsulorrhexis size, and bag diffusiveness. Results demonstrated the optical basis of negative dysphotopsia. We found that photic structures were mainly influenced by critical factors such as the capsulorrhexis size and the optical diffusiveness of the capsular bag. The simulations suggested the hypothesis that the anterior capsulorrhexis interacting with intraocular lens could induce negative dysphotopsia.
authors.affiliation: Alcon Laboratories, 6201 South Freeway, Fort Worth, Texas 76134, USA. xin.hong@alconlabs.com
authors.forename: Xin
authors.initials: X
authors.lastname: Hong
authors.forename: Yueai
authors.initials: Y
authors.lastname: Liu
authors.forename: Mutlu
authors.initials: M
authors.lastname: Karakelle
authors.forename: Samuel
authors.initials: S
authors.lastname: Masket
authors.forename: Nicole R
authors.initials: NR
authors.lastname: Fram
mesh_terms: D019923:Capsulorhexis / Q000009:adverse effects*; D003198:Computer Simulation; D006801:Humans; D007910:Lenses, Intraocular; D008954:Models, Biological; D011680:Pupil / Q000502:physiology; D012160:Retina / Q000502:physiology; D013057:Spectrum Analysis / Q000379:methods*; D014786:Vision Disorders / Q000503:physiopathology*; D014785:Vision, Ocular / Q000502:physiology