title: Antibiotic desensitization therapy in secondary syphilis and Listeria infection: case reports and review of desensitization therapy.
abstract: Two adult cases, one of secondary syphilis and one of Listeria monocytogenes bacteremia, in which antibiotic desensitization therapy was utilized to assist treatment of active infection in the face of severe penicillin allergy. Clinical considerations are discussed that led to the decision to employ a formal desensitization procedure. Antibiotic desensitization protocols can facilitate optimal and safe antibiotic therapy in the appropriate clinical setting.
authors.affiliation: Department of Internal Medicine, Tripler Army Medical Center, Honolulu, HI 96859, USA.
authors.forename: Gil
authors.initials: G
authors.lastname: Magpantay
authors.forename: Anthony P
authors.initials: AP
authors.lastname: Cardile
authors.forename: Cristian S
authors.initials: CS
authors.lastname: Madar
authors.forename: Gunther
authors.initials: G
authors.lastname: Hsue
authors.forename: Conrad
authors.initials: C
authors.lastname: Belnap
mesh_terms: D000368:Aged; D000667:Ampicillin / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D003888:Desensitization, Immunologic; D004342:Drug Hypersensitivity; D005260:Female; D006801:Humans; D008089:Listeria monocytogenes; D008088:Listeriosis / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D010406:Penicillins / Q000627:therapeutic use; D013587:Syphilis / Q000188:drug therapy*
chemical_list: D000900:Anti-Bacterial Agents; D010406:Penicillins; D000667:Ampicillin