title: Clinical outcomes of laparoscopic surgery for advanced transverse and descending colon cancer: a single-center experience.
abstract: BACKGROUND
  The role of laparoscopic surgery in management of transverse and descending colon cancer remains controversial. The aim of the present study is to investigate the short-term and oncologic long-term outcomes associated with laparoscopic surgery for transverse and descending colon cancer.
  
  
  METHODS
  This cohort study analyzed 245 patients (stage II disease, n = 70; stage III disease, n = 63) who underwent resection of transverse and descending colon cancers, including 200 laparoscopic surgeries (LAC) and 45 conventional open surgeries (OC) from December 1996 to December 2010. Short-term and oncologic long-term outcomes were recorded.
  
  
  RESULTS
  The operative time was longer in the LAC group than in the OC group. However, intraoperative blood loss was significantly lower and postoperative recovery time was significantly shorter in the LAC group than in the OC group. The 5-year overall and disease-free survival rates for patients with stage II were 84.9% and 84.9% in the OC group and 93.7% and 90.0% in the LAC group, respectively. The 5-year overall and disease-free survival rates for patients with stage III disease were 63.4% and 54.6% in the OC group and 66.7% and 56.9% in the LAC group, respectively.
  
  
  CONCLUSIONS
  Use of laparoscopic surgery resulted in acceptable short-term and oncologic outcomes in patients with advanced transverse and descending colon cancer.
authors.affiliation: Departments of General and Gastroenterological Surgery, Osaka Medical College Hospital, 2-7 Daigakumachi, Takatsuki, Osaka 569-8686, Japan.
authors.forename: Masashi
authors.initials: M
authors.lastname: Yamamoto
authors.forename: Junji
authors.initials: J
authors.lastname: Okuda
authors.forename: Keitaro
authors.initials: K
authors.lastname: Tanaka
authors.forename: Keisaku
authors.initials: K
authors.lastname: Kondo
authors.forename: Nobuhiko
authors.initials: N
authors.lastname: Tanigawa
authors.forename: Kazuhisa
authors.initials: K
authors.lastname: Uchiyama
mesh_terms: D000368:Aged; D016063:Blood Loss, Surgical; D015331:Cohort Studies; D003082:Colectomy / Q000379:methods* / Q000401:mortality; D044683:Colon, Descending / Q000601:surgery*; D003110:Colonic Neoplasms / Q000401:mortality / Q000601:surgery*; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D010535:Laparoscopy / Q000379:methods* / Q000401:mortality; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000209:etiology / Q000401:mortality; D016896:Treatment Outcome