title: Fatal parvovirus B19 myocarditis in children and possible dysimmune mechanism.
abstract: We report 2 cases of previously healthy children, who developed, after a common parvovirus B19 infection, a sudden inflammatory response, involving predominantly T cell, directed against myocardium and leading to fatal outcome. These cases and several published case reports further our understanding of fulminating parvovirus myocarditis in children.
authors.affiliation: Service de Réanimation Pédiatrique, Hôpital Necker-Enfants Malades, Paris, France. koehl.berengere@gmail.com
authors.forename: Berengere
authors.initials: B
authors.lastname: Koehl
authors.forename: Mehdi
authors.initials: M
authors.lastname: Oualha
authors.forename: Fabrice
authors.initials: F
authors.lastname: Lesage
authors.forename: Caroline
authors.initials: C
authors.lastname: Rambaud
authors.forename: Danielle
authors.initials: D
authors.lastname: Canioni
authors.forename: Philippe
authors.initials: P
authors.lastname: Hubert
authors.forename: Marianne
authors.initials: M
authors.lastname: Leruez-Ville
mesh_terms: D002675:Child, Preschool; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D009205:Myocarditis / Q000175:diagnosis* / Q000276:immunology / Q000473:pathology* / Q000821:virology; D009206:Myocardium / Q000276:immunology / Q000473:pathology; D010322:Parvoviridae Infections / Q000175:diagnosis* / Q000276:immunology / Q000473:pathology* / Q000821:virology; D016732:Parvovirus B19, Human / Q000276:immunology / Q000302:isolation & purification* / Q000472:pathogenicity; D013601:T-Lymphocytes / Q000276:immunology