title: Targeting liver cancer: first steps toward a miRacle?
abstract: In a recent issue of Cell, Iliopoulos and colleagues demonstrate a novel and targetable epigenetic amplification loop in hepatocellular carcinoma involving HNF4α, miR-124, IL6-R, Stat3, miR-24, and miR-629. These results establish microRNAs as novel players in early stages of hepatocarcinogenesis and as potential targets for the treatment of hepatocellular carcinoma.
authors.affiliation: Department of Medicine, Columbia University, New York, NY 10032, USA. rfs2102@columbia.edu
authors.forename: Robert F
authors.initials: RF
authors.lastname: Schwabe
authors.forename: Timothy C
authors.initials: TC
authors.lastname: Wang