title: Outcomes of pregnancies complicated by hyperemesis gravidarum.
abstract: OBJECTIVE
  To evaluate maternal and fetal outcomes among women with hyperemesis gravidarum (HG).
  
  
  METHODS
  In a university hospital and a research and training hospital, a retrospective cohort study was conducted among women with singleton deliveries between 2003 and 2011. Maternal outcomes evaluated included gestational diabetes, pregnancy-induced hypertension, cesarean delivery. Neonatal outcomes also determined were 5-min Apgar score of less than 7, low birth weight, small for gestational age (SGA), preterm delivery, fetal sex, and stillbirth.
  
  
  RESULTS
  There were no statistical differences in the mean of age, parity, the number of artificial pregnancy, and smoking between two groups. Infants from HG pregnancies manifested similar birth weight (3,121.5 ± 595.4 vs. 3,164 ± 664.5 g) and gestational age (38.1 ± 2.3 vs. 38.1 ± 2.6 weeks), relative to infants from the control group (p = 0.67 and 0.91, respectively). In addition, no statistical significant differences were found in the rates of SGA birth, preterm birth, gestational diabetes, pregnancy-induced hypertension, and adverse fetal outcome between two groups (p > 0.05). Cesarean delivery rates were similar in two groups (31.9% in hyperemesis group vs. 27% in control group, p = 0.49). Comparing the gender of the newborn baby and Apgar scores less than 7 at 5 min, there were no statistically significant differences between two groups (p = 0.16 and 0.42, respectively).
  
  
  CONCLUSIONS
  Hyperemesis gravidarum is not associated with adverse pregnancy outcomes.
authors.affiliation: Department of Obstetrics and Gynecology, Kanuni Sultan Süleyman Research and Training Hospital, Seyidömer Mah. Köprülüzade Sok. No:5/4, Fatih, 34098 Istanbul, Turkey. drokuru@yahoo.com
authors.forename: Oguzhan
authors.initials: O
authors.lastname: Kuru
authors.forename: Serhat
authors.initials: S
authors.lastname: Sen
authors.forename: Ozgur
authors.initials: O
authors.lastname: Akbayır
authors.forename: B Pinar Cilesiz
authors.initials: BP
authors.lastname: Goksedef
authors.forename: Mehmet
authors.initials: M
authors.lastname: Ozsürmeli
authors.forename: Erkut
authors.initials: E
authors.lastname: Attar
authors.forename: Halil
authors.initials: H
authors.lastname: Saygılı
mesh_terms: D000328:Adult; D001034:Apgar Score; D002585:Cesarean Section / Q000706:statistics & numerical data; D016640:Diabetes, Gestational / Q000453:epidemiology / Q000209:etiology; D005260:Female; D006801:Humans; D006939:Hyperemesis Gravidarum / Q000150:complications* / Q000453:epidemiology; D046110:Hypertension, Pregnancy-Induced / Q000453:epidemiology / Q000209:etiology; D015994:Incidence; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D007236:Infant, Small for Gestational Age; D008297:Male; D011247:Pregnancy; D011256:Pregnancy Outcome / Q000453:epidemiology*; D047928:Premature Birth / Q000453:epidemiology; D012189:Retrospective Studies