title: HDAC inhibition prevents Rd1 mouse photoreceptor degeneration.
authors.affiliation: Department of Ophthalmology, Columbia University, New York, NY 10032, USA. fjs2115@columbia.edu
authors.forename: Javier
authors.initials: J
authors.lastname: Sancho-Pelluz
authors.forename: François
authors.initials: F
authors.lastname: Paquet-Durand
mesh_terms: D000818:Animals; D016923:Cell Death / Q000187:drug effects / Q000502:physiology; D002478:Cells, Cultured; D054707:Cyclic Nucleotide Phosphodiesterases, Type 6 / Q000235:genetics*; D015870:Gene Expression / Q000502:physiology; D056284:Histone Deacetylase 1 / Q000037:antagonists & inhibitors* / Q000378:metabolism; D056572:Histone Deacetylase Inhibitors / Q000494:pharmacology; D006877:Hydroxamic Acids / Q000494:pharmacology*; D051379:Mice; D008809:Mice, Inbred C3H; D018696:Neuroprotective Agents / Q000494:pharmacology; D020419:Photoreceptor Cells, Vertebrate / Q000187:drug effects / Q000378:metabolism / Q000473:pathology; D000071137:Poly (ADP-Ribose) Polymerase-1; D011065:Poly(ADP-ribose) Polymerases / Q000378:metabolism; D012174:Retinitis Pigmentosa / Q000188:drug therapy* / Q000235:genetics / Q000378:metabolism
chemical_list: D056572:Histone Deacetylase Inhibitors; D006877:Hydroxamic Acids; D018696:Neuroprotective Agents; C012589:trichostatin A; C499321:Parp1 protein, mouse; D000071137:Poly (ADP-Ribose) Polymerase-1; D011065:Poly(ADP-ribose) Polymerases; D054707:Cyclic Nucleotide Phosphodiesterases, Type 6; C517438:Pde6b protein, mouse; C484389:Hdac1 protein, mouse; D056284:Histone Deacetylase 1