title: Coeliac disease and granulomatous ileocolitis: an association or chance occurrence?
abstract: Enteric granulomatous inflammation can be caused by a number of conditions including Crohn's disease, sarcoidosis, enteric infections, chronic granulomatous disease and also by drug reactions. Granulomas have also been described in microscopic colitis associated with certain medications and autoimmune diseases. The association of granulomatous ileocolitis with coeliac disease is not common. We present a case of coeliac disease with granulomatous ileocolitis with follow-up and repeat histology on a gluten-free diet. We discuss the pathological mechanisms leading to the association of granulomatous ileocolitis with coeliac disease as well as other conditions.
authors.affiliation: Department of Gastroenterology, County Durham & Darlington NHS Foundation Trust, Cockton Hill Road, Co. Durham, DL14 6AD, UK.
authors.forename: C E
authors.initials: CE
authors.lastname: Johns
authors.forename: J H
authors.initials: JH
authors.lastname: Topping
authors.forename: C
authors.initials: C
authors.lastname: Bloxham
authors.forename: A
authors.initials: A
authors.lastname: Dhar
mesh_terms: D002446:Celiac Disease / Q000150:complications* / Q000178:diet therapy / Q000473:pathology; D003424:Crohn Disease / Q000150:complications* / Q000473:pathology; D055050:Diet, Gluten-Free; D005260:Female; D005500:Follow-Up Studies; D006099:Granuloma / Q000150:complications* / Q000473:pathology; D006801:Humans; D007249:Inflammation / Q000209:etiology*; D008875:Middle Aged