title: Endothelial cell loss associated with diffuse lamellar keratitis because of laser-assisted in situ keratomileusis.
abstract: OBJECTIVE
  To report a case of severe interface inflammation, flap edema, and endothelial cell loss after laser-assisted in situ keratomileusis (LASIK).
  
  
  METHODS
  A 22-year-old woman with no previous ocular abnormality underwent LASIK for myopia. The surgery was uneventful. Her preoperative endothelial count was 3,066 and 2,898 cells per square millimeter OD and OS, respectively.
  
  
  RESULTS
  On the first postoperative day, the right eye had interface infiltrates, flap edema, and radiating Descemet's folds and the left eye had flap edema with interface infiltrates. Bilateral flap relifts and thorough irrigation were performed on the second day, followed by amputation of the nonviable flap in the right eye on the third day. On medical management, the corneal edema resolved for more than 1 month. At 6 months, the best-corrected vision was 20/32 OD and 20/25 OS, with endothelial cell count of 1,763 and 2,055 cells per square millimeter OD and OS, respectively.
  
  
  CONCLUSIONS
  Endothelial status should be monitored in patients with a severe interface reaction or severe diffuse lamellar keratitis after LASIK.
authors.affiliation: Dr. Agarwal's Eye Hospital and Eye Research Centre, Chennai, India.
authors.forename: Prashaant
authors.initials: P
authors.lastname: Chaudhry
authors.forename: Gaurav
authors.initials: G
authors.lastname: Prakash
authors.forename: Amar
authors.initials: A
authors.lastname: Agarwal
authors.forename: Anjum Iqbal
authors.initials: AI
authors.lastname: Mazhari
authors.forename: Dhivya Ashok
authors.initials: DA
authors.lastname: Kumar
authors.forename: Athiya
authors.initials: A
authors.lastname: Agarwal
authors.forename: Soosan
authors.initials: S
authors.lastname: Jacob
mesh_terms: D015715:Corneal Edema / Q000209:etiology*; D004728:Endothelium, Corneal / Q000473:pathology; D005260:Female; D006801:Humans; D007634:Keratitis / Q000209:etiology*; D020731:Keratomileusis, Laser In Situ / Q000009:adverse effects*; D054018:Lasers, Excimer / Q000009:adverse effects*; D009216:Myopia / Q000601:surgery; D013524:Surgical Flaps / Q000473:pathology; D055815:Young Adult