title: Transcatheter aortic valve implantation and simultaneous closure of ostium secundum atrial septal defect.
abstract: We were faced with a difficult question: how to treat a high-risk patient with severe aortic valve stenosis and a secundum atrial septal defect (ASD II). An 85-year-old woman with progressive dyspnea and pedal edema and in New York Heart Association class IV was treated with concomitant transapical aortic valve implantation and transcatheter closure of the ASD II. The combined procedure and postoperative course were completely uneventful. At 2 years after the clinical follow-up, the patient is doing well. This case report demonstrates, for the first time, the feasibility, safety, and effectiveness of simultaneous application of 2 transcatheter methods--aortic valve implantation and closure of an ASD II. As surgeons, we should consider percutaneous treatment of combined structural heart disease in patients at high risk for conventional surgery.
authors.affiliation: Deutsches Herzzentrum Berlin, Berlin, Germany. pasic@dhzb.de
authors.forename: Miralem
authors.initials: M
authors.lastname: Pasic
authors.forename: Felix
authors.initials: F
authors.lastname: Berger
authors.forename: Giuseppe
authors.initials: G
authors.lastname: D'Ancona
authors.forename: Stephan
authors.initials: S
authors.lastname: Dreysse
authors.forename: Semih
authors.initials: S
authors.lastname: Buz
authors.forename: Thorsten
authors.initials: T
authors.lastname: Drews
authors.forename: Roland
authors.initials: R
authors.lastname: Hetzer
authors.forename: Axel
authors.initials: A
authors.lastname: Unbehaun
authors.forename: Marian
authors.initials: M
authors.lastname: Kukucka
mesh_terms: D000369:Aged, 80 and over; D001024:Aortic Valve Stenosis / Q000150:complications / Q000000981:diagnostic imaging / Q000601:surgery*; D006328:Cardiac Catheterization; D017023:Coronary Angiography; D004452:Echocardiography; D005260:Female; D006344:Heart Septal Defects, Atrial / Q000150:complications / Q000000981:diagnostic imaging / Q000601:surgery*; D019918:Heart Valve Prosthesis Implantation / Q000379:methods*; D006801:Humans