title: Sequence variation at the oxygen-evolving centre of photosystem II: a new class of 'rogue' cyanobacterial D1 proteins.
abstract: Photosystem II is the oxygen-evolving enzyme of photosynthesis. It is a membrane-bound protein-pigment complex. The oxygen is produced at the oxygen-evolving centre (OEC), a Mn(4)CaO(5) metallocluster, which is largely ligated by amino acids of the D1 protein. The OEC-ligating residues are invariant between most cyanobacteria and higher plants. In this study, a new class of cyanobacterial D1 proteins has been identified in which the OEC metal-ligating residues are very different to the consensus. This new class of 'rogue' D1 proteins is associated with diazotrophic cyanobacteria. Their function, activity and origins are discussed.
authors.affiliation: Division of Molecular Biosciences, Imperial College, Exhibition Road, London, SW7 2AZ, UK. j.w.murray@imperial.ac.uk
authors.forename: James W
authors.initials: JW
authors.lastname: Murray
mesh_terms: D000595:Amino Acid Sequence; D001426:Bacterial Proteins / Q000737:chemistry / Q000378:metabolism; D016384:Consensus Sequence; D000458:Cyanobacteria / Q000378:metabolism*; D008958:Models, Molecular; D008969:Molecular Sequence Data; D010100:Oxygen / Q000378:metabolism*; D045332:Photosystem II Protein Complex / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism*; D010802:Phylogeny; D016415:Sequence Alignment; D020539:Sequence Analysis, Protein
chemical_list: D001426:Bacterial Proteins; D045332:Photosystem II Protein Complex; C422369:photosystem II, psbA subunit; D010100:Oxygen