title: Analyzing and mapping sweat metabolomics by high-resolution NMR spectroscopy.
abstract: The content of human sweat is studied by high-resolution NMR, and the majority of organic components most often found in sweat of conditionally healthy people are identified. Original and simple tools are designed for sweat sampling from different areas of human body. The minimal surface area needed for sampling is in the range of 50-100 cm(2). On all the surface parts of the human body examined in this work, the main constituents forming a sweat metabolic profile are lactate, glycerol, pyruvate, and serine. The only exception is the sole of the foot (planta pedis), where trace amounts of glycerol are found. An attempt is made to explain the presence of specified metabolites and their possible origin.
authors.affiliation: Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino, Moscow Region, Russia. kutyshenko@rambler.ru
authors.forename: Viktor P
authors.initials: VP
authors.lastname: Kutyshenko
authors.forename: Maxim
authors.initials: M
authors.lastname: Molchanov
authors.forename: Peter
authors.initials: P
authors.lastname: Beskaravayny
authors.forename: Vladimir N
authors.initials: VN
authors.lastname: Uversky
authors.forename: Maria A
authors.initials: MA
authors.lastname: Timchenko
mesh_terms: D000328:Adult; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D008297:Male; D055432:Metabolomics; D008875:Middle Aged; D013542:Sweat / Q000378:metabolism*