title: Copper-catalyzed one-pot synthesis of imidazo/benzoimidazoquinazolinones by sequential Ullmann-type coupling and intramolecular C-H amidation.
abstract: A simple, practical, and highly efficient copper-catalyzed one-pot synthesis of imidazo/benzoimidazoquinazolinones has been developed. The procedure is based on a sequential copper-catalyzed Ullmann-type N-arylation and aerobic oxidative intramolecular C-H amidation. This method should provide a new and useful strategy for construction of N-heterocycles.
authors.affiliation: Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University, Beijing 100084, P.R. China
authors.forename: Hao
authors.initials: H
authors.lastname: Xu
authors.forename: Hua
authors.initials: H
authors.lastname: Fu
mesh_terms: D000577:Amides / Q000138:chemical synthesis / Q000737:chemistry*; D001391:Azo Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D007093:Imidazoles / Q000138:chemical synthesis / Q000737:chemistry*; D015394:Molecular Structure; D052999:Quinazolinones / Q000138:chemical synthesis / Q000737:chemistry*
chemical_list: D000577:Amides; D001391:Azo Compounds; D007093:Imidazoles; D052999:Quinazolinones; D003300:Copper