title: Serum procalcitonin value is useful for predicting severity of Kawasaki disease.
abstract: We measured serum procalcitonin concentrations in 160 patients suffering from Kawasaki disease. Serum procalcitonin was significantly higher in nonresponders to an initial intravenous immunoglobulin treatment than in responders. A cutoff value of procalcitonin (0.5 ng/mL) for nonresponders showed that the sensitivity was 85% and the accuracy was 64%. Multivariate logistic regression analysis revealed that procalcitonin-positive cases showed the highest risk for nonresponders.
authors.affiliation: Department of Pediatrics, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan.
authors.forename: Hideki
authors.initials: H
authors.lastname: Yoshikawa
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Nomura
authors.forename: Kiminori
authors.initials: K
authors.lastname: Masuda
authors.forename: Chihaya
authors.initials: C
authors.lastname: Koriya
authors.forename: Michiko
authors.initials: M
authors.lastname: Arata
authors.forename: Daisuke
authors.initials: D
authors.lastname: Hazeki
authors.forename: Kosuke
authors.initials: K
authors.lastname: Yanagimoto
authors.forename: Kentaro
authors.initials: K
authors.lastname: Ueno
authors.forename: Taisuke
authors.initials: T
authors.lastname: Eguchi
authors.forename: Yoshifumi
authors.initials: Y
authors.lastname: Kawano
mesh_terms: D002116:Calcitonin / Q000097:blood*; D015740:Calcitonin Gene-Related Peptide; D002675:Child, Preschool; D005260:Female; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D007223:Infant; D008297:Male; D009080:Mucocutaneous Lymph Node Syndrome / Q000175:diagnosis / Q000503:physiopathology* / Q000628:therapy; D011237:Predictive Value of Tests; D011379:Prognosis; D011498:Protein Precursors / Q000097:blood*; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index
chemical_list: C000606589:CALCA protein, human; D016756:Immunoglobulins, Intravenous; D011498:Protein Precursors; D002116:Calcitonin; D015740:Calcitonin Gene-Related Peptide