title: Broadband superluminescent diode-based ultrahigh resolution optical coherence tomography for ophthalmic imaging.
abstract: Spectral domain optical coherence tomography (SD-OCT) with ultrahigh resolution can be used to measure precise structures in the context of ophthalmic imaging. We designed an ultrahigh resolution SD-OCT system based on broadband superluminescent diode (SLD) as the light source. An axial resolution of 2.2 μm in tissue, a scan depth of 1.48 mm, and a high sensitivity of 93 dB were achieved by the spectrometer designed. The ultrahigh-resolution SD-OCT system was employed to image the human cornea and retina with a cross-section image of 2048 × 2048 pixels. Our research demonstrated that ultrahigh -resolution SD-OCT can be achieved using broadband SLD in a simple way.
authors.affiliation: Wenzhou Medical College, School of Ophthalmology and Optometry, Wenzhou, Zhejiang 325000, China.
authors.forename: Dexi
authors.initials: D
authors.lastname: Zhu
authors.forename: Meixiao
authors.initials: M
authors.lastname: Shen
authors.forename: Hong
authors.initials: H
authors.lastname: Jiang
authors.forename: Ming
authors.initials: M
authors.lastname: Li
authors.forename: Michael R
authors.initials: MR
authors.lastname: Wang
authors.forename: Yuhong
authors.initials: Y
authors.lastname: Wang
authors.forename: Lili
authors.initials: L
authors.lastname: Ge
authors.forename: Jia
authors.initials: J
authors.lastname: Qu
authors.forename: Jianhua
authors.initials: J
authors.lastname: Wang
mesh_terms: D003315:Cornea / Q000033:anatomy & histology; D006801:Humans; D007091:Image Processing, Computer-Assisted; D009887:Ophthalmoscopy / Q000379:methods*; D012160:Retina / Q000033:anatomy & histology; D012680:Sensitivity and Specificity; D041623:Tomography, Optical Coherence / Q000379:methods*