title: Barostat or dynamic balloon distention test: which technique is best suited for esophageal sensory testing?
abstract: Esophageal sensation is commonly assessed by barostat-assisted balloon distension (BBD) or dynamic balloon distension (DBD) technique, but their relative merits are unknown. Our aim was to compare the usefulness and tolerability of both techniques. Sixteen healthy volunteers (male/female = 6/10) randomly underwent graded esophageal balloon distensions, using either BBD (n= 8) or DBD (n= 8). BBD was performed by placing a 5-cm long highly compliant balloon attached to a barostat, and DBD by placing a 5-cm long balloon attached to a leveling container. Intermittent phasic balloon distensions were performed in increments of 6 mm Hg. Sensory thresholds and biomechanical properties were assessed and compared. Sensory thresholds for first perception (mean ± standard deviation; 21 ± 6 vs. 21.2 ± 5, mm Hg, P= 0.9), discomfort (38 ± 8 vs. 35 ± 9, P= 0.5), and pain (44 ± 4 vs. 45 ± 3, P= 0.7) were similar with BBD and DBD techniques. However, more subjects tolerated DBD (7/8, 88%) when compared with BBD (4/8, 50%). Forceful expulsion of balloon into stomach (n= 4), pulling around the mouth (n= 4), chest discomfort (n= 2) and retching (n= 2) were overlapping reasons for intolerance with BBD. Esophageal wall distensibility was similar with both techniques. Both techniques provided comparable data on biomechanical properties. However, DBD was better tolerated than BBD for evaluation of esophageal sensation. Hence, we recommend DBD for performing esophageal balloon distension test.
authors.affiliation: Division of Neurogastroenterology and Motility, Department of Internal Medicine and Clinical Translational Research Center, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA.
authors.forename: J M
authors.initials: JM
authors.lastname: Remes-Troche
authors.forename: A
authors.initials: A
authors.lastname: Attaluri
authors.forename: P
authors.initials: P
authors.lastname: Chahal
authors.forename: S S C
authors.initials: SS
authors.lastname: Rao
mesh_terms: D000328:Adult; D002404:Catheterization / Q000379:methods*; D002637:Chest Pain / Q000175:diagnosis* / Q000209:etiology; D004935:Esophageal Diseases / Q000150:complications / Q000175:diagnosis*; D004947:Esophagus / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008297:Male; D011312:Pressure; D011897:Random Allocation; D012677:Sensation; D012684:Sensory Thresholds; D020886:Somatosensory Disorders / Q000150:complications / Q000175:diagnosis*