title: Use of thrombocyte concentrates in treatment of bone defects.
abstract: The use of plasma enriched with thrombocytes is a trend in surgical treatment of bone defects (Platelet-rich plasma, thrombocyte concentrate, hereinafter PRP). It contains a set of identified as well as unknown growth factors. It is nontoxic, has no immunity reaction, accelerates and improves the healing of wounds. The increased level of growth factors leads to improved formation of new bone matter, and at the same time speeds up healing of soft tissues surrounding the bones. In addition, the presence of various factors mutually modulates and influences their functions. These functions are specific and differentiate the growth factors from recombinant growth factors, which are simple and focus just on one regenerating operation. PRP and ABPG (autologous bone-platelet gel) are used for augmentations in implantology, alveolar injuries with loss, treatment of parodontopathies, cleavages, and for osteodistraction of atrophic mandibles (Ref. 24).
authors.affiliation: Department of Stomatology and Maxilofacial Surgery, Faculty of Medicine, Comenius University, Bratislava, Slovakia. bll@fmed.uniba.sk
authors.forename: T
authors.initials: T
authors.lastname: Feltsan
authors.forename: J
authors.initials: J
authors.lastname: Mracna
authors.forename: D
authors.initials: D
authors.lastname: Holly
mesh_terms: D001861:Bone Regeneration; D006801:Humans; D053657:Platelet-Rich Plasma; D014945:Wound Healing