title: Methods specification for diagnostic test accuracy studies in fine-needle aspiration cytology: a survey of reporting practice.
abstract: Diagnostic test accuracy (DTA) studies on fine-needle aspiration cytology (FNAC) often show considerable variability in diagnostic accuracy between study centers. Many factors affect the accuracy of FNAC. A complete description of the testing parameters would help make valid comparisons between studies and determine causes of performance variation. We investigated the manner in which test conditions are specified in FNAC DTA studies to determine which parameters are most commonly specified and the frequency with which they are specified and to see whether there is significant variability in reporting practice. We identified 17 frequently reported test parameters and found significant variation in the reporting of these test specifications across studies. On average, studies reported 5 of the 17 items that would be required to specify the test conditions completely. A more complete and standardized reporting of methods, perhaps by means of a checklist, would improve the interpretation of FNAC DTA studies.
authors.affiliation: Department of Pathology, University of Utah, Salt Lake City, UT 84112, USA.
authors.forename: Robert L
authors.initials: RL
authors.lastname: Schmidt
authors.forename: Rachel E
authors.initials: RE
authors.lastname: Factor
authors.forename: Kajsa E
authors.initials: KE
authors.lastname: Affolter
authors.forename: Joshua B
authors.initials: JB
authors.lastname: Cook
authors.forename: Brian J
authors.initials: BJ
authors.lastname: Hall
authors.forename: Krishna K
authors.initials: KK
authors.lastname: Narra
authors.forename: Benjamin L
authors.initials: BL
authors.lastname: Witt
authors.forename: Andrew R
authors.initials: AR
authors.lastname: Wilson
authors.forename: Lester J
authors.initials: LJ
authors.lastname: Layfield
mesh_terms: D044963:Biopsy, Fine-Needle / Q000379:methods* / Q000592:standards; D057189:Checklist; D003951:Diagnostic Errors / Q000706:statistics & numerical data*; D006801:Humans; D008485:Medical Audit / Q000379:methods; D011364:Professional Practice; D015203:Reproducibility of Results; D012107:Research Design; D013048:Specimen Handling / Q000379:methods* / Q000592:standards