title: [Early diagnosis of metastatic spinal tumor is a key for effective palliative radiotherapy in patients with lung cancer].
abstract: Patients with metastatic spinal tumor are the largest in number among the patients with bone tumor. It causes a severe bone pain, pathological fracture and spinal cord compression. Thus it harshly hampers patient's quality of life. We report 3 patients with lung cancer whose initial manifestation was metastatic spinal tumor. We treated the 3 patients with palliative radiotherapy and medication. Although the severe pain has improved on a numerical rating scale(NRS), but performance status(PS)and activity of daily living(ADL)of the 3 patients got worse because the disease was progressed and complicated. Generally, PS of cancer patients found by bone matastasis is low. However, it is difficult to take an effective treatment, which leads to ADL improvement. There are many choices for treating metastatic bone tumors including pain control, bisphosphonate administration, radiation therapy, strontium radiotherapy, bone cement, palliative surgery and orthotics. In addition, a development of molecular target drugs, such as Denosmab, is expected as future modality of palliative care. In conclusion, we should detect a bone metastasis in the patient with lung cancer as early as possible, and select an appropriate treatment in collaboration with each specialist for achieving the ADL and PS improvement.
authors.affiliation: Dept. of Internal Medicine, Keiyu Hospital.
authors.forename: Hisayo
authors.initials: H
authors.lastname: Isono
authors.forename: Tomoko
authors.initials: T
authors.lastname: Kemmoku
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Nakamura
authors.forename: Akira
authors.initials: A
authors.lastname: Onose
authors.forename: Yuka
authors.initials: Y
authors.lastname: Matsumoto
authors.forename: Rinako
authors.initials: R
authors.lastname: Watanabe
authors.forename: Mizuha
authors.initials: M
authors.lastname: Haraguchi
authors.forename: Masashi
authors.initials: M
authors.lastname: Kasajima
authors.forename: Saho
authors.initials: S
authors.lastname: Takaya
authors.forename: Mikiko
authors.initials: M
authors.lastname: Ishihara
authors.forename: Daiki
authors.initials: D
authors.lastname: Karigane
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Nagata
mesh_terms: D000368:Aged; D055088:Early Detection of Cancer; D017809:Fatal Outcome; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology*; D008297:Male; D010166:Palliative Care; D013120:Spinal Cord Neoplasms / Q000175:diagnosis / Q000532:radiotherapy* / Q000556:secondary