title: Assessment of a five-year survival on hemodialysis in Brazil: a cohort of 3,082 incident patients.
abstract: Brazil has the third largest contingent of patients on maintenance hemodialysis (HD) worldwide. However, little is known regarding survival rate and predictors of mortality risk in that population, which are the purposes of this study. A total of 3,082 patients incident on HD, from 2000 to 2004, at 25 dialysis facilities distributed among 7 out of 26 states of Brazil were followed-up until 2009. Patients were 52 ± 16 years-old, 57.8% men, and 20.4%, diabetics. The primary outcome was all causes of mortality. Data were censored at five years of follow-up. The global five-year survival rate was 58.2%. In the Cox proportional model, variables associated with risk of death were: age (hazard ratio - HR = 1.44 per decade, p < 0.0001), diabetes (HR = 1.51, p < 0.0001), serum albumin (HR = 0.76 per g/dL, p = 0.001), creatinine (HR = 0.92 per mg/dL, p < 0.0001), and phosphorus (HR = 1.06 per mg/dL, p = 0.04). The present results show that the mortality rate on HD in this Brazilian cohort was relatively low, but the population is younger and with a lower prevalence of diabetes than the ones reported for developed countries.
authors.affiliation: Division of Nephrology, Faculdade de Medicina, Universidade Federal Fluminense, Niterói, Brazil. strogoff@uol.com.br
authors.forename: Jorge Paulo Strogoff de
authors.initials: JP
authors.lastname: Matos
authors.forename: Jorge Reis
authors.initials: JR
authors.lastname: Almeida
authors.forename: Adrian
authors.initials: A
authors.lastname: Guinsburg
authors.forename: Cristina
authors.initials: C
authors.lastname: Marelli
authors.forename: Ana Beatriz Lesqueves
authors.initials: AB
authors.lastname: Barra
authors.forename: Marcos Sandro
authors.initials: MS
authors.lastname: Vasconcellos
authors.forename: Eufrônio
authors.initials: E
authors.lastname: José D'Almeida Filho
authors.forename: Marcos
authors.initials: M
authors.lastname: Hoette
authors.forename: Frederico
authors.initials: F
authors.lastname: Ruzany
authors.forename: Jocemir Ronaldo
authors.initials: JR
authors.lastname: Lugon
mesh_terms: D000328:Adult; D001938:Brazil / Q000453:epidemiology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis / Q000401:mortality*; D012189:Retrospective Studies; D018570:Risk Assessment; D015996:Survival Rate; D013997:Time Factors