title: Preparation and characterization of targeted DOX-PLGA-PEG micelles decorated with bivalent fragment HAb18 F(ab')2 for treatment of hepatocellular carcinoma.
authors.affiliation: Department of Hepatobiliary Surgery, Xijing Hospital, Tangdu Hospital, Fourth Military Medical University, Xi'an 710032, China.
authors.forename: Cheng
authors.initials: C
authors.lastname: Jin
authors.forename: Wenqing
authors.initials: W
authors.lastname: Yang
authors.forename: Ling
authors.initials: L
authors.lastname: Bai
authors.forename: Junqing
authors.initials: J
authors.lastname: Wang
authors.forename: Kefeng
authors.initials: K
authors.lastname: Dou
mesh_terms: D000818:Animals; D000903:Antibiotics, Antineoplastic / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology*; D000911:Antibodies, Monoclonal / Q000737:chemistry / Q000378:metabolism*; D006528:Carcinoma, Hepatocellular / Q000188:drug therapy* / Q000276:immunology / Q000378:metabolism; D002626:Chemistry, Pharmaceutical; D004317:Doxorubicin / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology*; D004337:Drug Carriers; D004339:Drug Compounding; D056945:Hep G2 Cells; D006801:Humans; D007140:Immunoglobulin Fab Fragments / Q000737:chemistry / Q000378:metabolism*; D000922:Immunotoxins / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology*; D007700:Kinetics; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000276:immunology / Q000378:metabolism; D009682:Magnetic Resonance Spectroscopy; D051379:Mice; D008819:Mice, Nude; D008823:Micelles; D008855:Microscopy, Electron, Scanning; D046529:Microscopy, Electron, Transmission; D008856:Microscopy, Fluorescence; D011092:Polyethylene Glycols / Q000737:chemistry*; D011098:Polyglactin 910 / Q000737:chemistry*; D012995:Solubility; D017550:Spectroscopy, Fourier Transform Infrared; D013678:Technology, Pharmaceutical / Q000379:methods; D014018:Tissue Distribution; D023041:Xenograft Model Antitumor Assays
chemical_list: D000903:Antibiotics, Antineoplastic; D000911:Antibodies, Monoclonal; D004337:Drug Carriers; D007140:Immunoglobulin Fab Fragments; D000922:Immunotoxins; D008823:Micelles; C102418:poly(lactic-glycolic acid)-poly(ethyleneglycol) copolymer; D011098:Polyglactin 910; D011092:Polyethylene Glycols; D004317:Doxorubicin