title: The Arabo-Islamic migrations in Madagascar: first genetic study of the GM system in three Malagasy populations.
abstract: The Antemoro are an ethnic group from the southeast coast of Madagascar who claims an Arab origin. Cultural signatures of an Arabo-Islamic influence have been found in this region. Nevertheless, their origins are very contentious. Through this study, we want to determine whether this ethnic group had a particular GM profile that differentiated it from other Malagasy populations, and whether there were detectable genetic traces of the Arabo-Islamic migration. The Gm polymorphisms of IgG immunoglobulins was analysed in a population of Antemoro (N = 85), two other Malagasy populations from northern Fihereňa (N = 82) and southern Fihereňa (N = 50) and in a Comorian population (N = 171). This last group was used to enlarge the database for genetic comparisons. Results revealed significant contributions from Africa (60%, 0.092 ≤F(ST) ≤ 0.280) and Southeast Asia (40%, 0.043 ≤ F(ST) ≤ 0.590) to the Antemoro genetic pool. No direct genetic relationships with the Middle East. These results bring new insights into the population history of Madagascar.
authors.affiliation: Laboratoire d'Anthropologie Moléculaire et Imagerie de Synthèse (AMIS), UMR 5288, CNRS, Université de Toulouse III, Paul Sabatier, Toulouse, France. m.capredon@yahoo.fr
authors.forename: M
authors.initials: M
authors.lastname: Capredon
authors.forename: A
authors.initials: A
authors.lastname: Sanchez-Mazas
authors.forename: E
authors.initials: E
authors.lastname: Guitard
authors.forename: H
authors.initials: H
authors.lastname: Razafindrazaka
authors.forename: J
authors.initials: J
authors.lastname: Chiaroni
authors.forename: B
authors.initials: B
authors.lastname: Champion
authors.forename: J-M
authors.initials: JM
authors.lastname: Dugoujon
mesh_terms: D018912:Arabs / Q000235:genetics*; D019295:Computational Biology; D016208:Databases, Factual; D004641:Emigration and Immigration; D005787:Gene Frequency; D005820:Genetic Testing; D014644:Genetic Variation; D005828:Genetics, Population; D006239:Haplotypes; D006801:Humans; D007129:Immunoglobulin Gm Allotypes / Q000097:blood / Q000235:genetics*; D008270:Madagascar / Q000208:ethnology; D010641:Phenotype; D011159:Population Surveillance
chemical_list: D007129:Immunoglobulin Gm Allotypes