title: [Hypothyroidism and cognition in the elderly].
abstract: The consequences of hypothyroidism on cognition are long known since the description of dementia associated with hypothyroidism. Additional data from experimental studies support the impact of thyroid hormones on the central nervous system and cognition. Cognitive impairment in relation with hypothyroidism (even sub clinical hypothyroidism) in elderly subjects involves memory, attention, and executive functions. Hypothyroidism may be associated with somatic, neurologic, psychiatric, social and environmental data. Cross-sectional and longitudinal studies are frequently heterogeneous but suggest a complex relationship between hypothyroidism and cognition.
authors.affiliation: Service de médecine interne gériatrique, CHRU de Tours.
authors.forename: Dominique
authors.initials: D
authors.lastname: Chavanne
authors.forename: Thierry
authors.initials: T
authors.lastname: Constans
authors.forename: Anne
authors.initials: A
authors.lastname: Petit
authors.forename: Karl
authors.initials: K
authors.lastname: Mondon
authors.forename: Caroline
authors.initials: C
authors.lastname: Hommet
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000818:Animals; D001921:Brain / Q000503:physiopathology; D060825:Cognitive Dysfunction / Q000175:diagnosis* / Q000503:physiopathology; D003430:Cross-Sectional Studies; D003704:Dementia / Q000175:diagnosis* / Q000503:physiopathology; D005260:Female; D006801:Humans; D007037:Hypothyroidism / Q000150:complications* / Q000175:diagnosis* / Q000503:physiopathology; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D013963:Thyroid Hormones / Q000097:blood; D055815:Young Adult
chemical_list: D013963:Thyroid Hormones