title: Translational vision research models program.
abstract: ENU mutagenesis is an efficient method to identify new animal models of ocular disease. The new alleles described herein will be a useful resource to further examine the role of the affected molecules and the effects of their disruption within the retina.
authors.affiliation: The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.
authors.forename: Jungyeon
authors.initials: J
authors.lastname: Won
authors.forename: Lan Ying
authors.initials: LY
authors.lastname: Shi
authors.forename: Wanda
authors.initials: W
authors.lastname: Hicks
authors.forename: Jieping
authors.initials: J
authors.lastname: Wang
authors.forename: Juergen K
authors.initials: JK
authors.lastname: Naggert
authors.forename: Patsy M
authors.initials: PM
authors.lastname: Nishina
mesh_terms: D000477:Alkylating Agents / Q000633:toxicity; D000818:Animals; D002874:Chromosome Mapping / Q000379:methods; D054707:Cyclic Nucleotide Phosphodiesterases, Type 6 / Q000235:genetics*; D004252:DNA Mutational Analysis / Q000379:methods; D004195:Disease Models, Animal; D005038:Ethylnitrosourea / Q000633:toxicity; D005136:Eye Proteins / Q000235:genetics*; D006801:Humans; D051379:Mice; D008810:Mice, Inbred C57BL; D016296:Mutagenesis / Q000502:physiology; D012162:Retinal Degeneration / Q000139:chemically induced / Q000235:genetics*; D012243:Rhodopsin / Q000235:genetics*; D057170:Translational Research, Biomedical / Q000379:methods
chemical_list: D000477:Alkylating Agents; D005136:Eye Proteins; C491353:Tulp1 protein, mouse; D012243:Rhodopsin; D054707:Cyclic Nucleotide Phosphodiesterases, Type 6; C498747:Pde6a protein, mouse; D005038:Ethylnitrosourea