title: Deep sequencing of small RNAs in plants: applied bioinformatics.
abstract: Small RNAs, including microRNA and short-interfering RNAs, play important roles in plants. In recent years, developments in sequencing technology have enabled the large-scale discovery of sRNAs in various cells, tissues and developmental stages and in response to various stresses. This review describes the bioinformatics challenges to analysing these large datasets of short-RNA sequences and some of the solutions to those challenges.
authors.affiliation: University of Exeter, Exeter EX4 4QD, UK. d.j.studholme@exeter.ac.uk
authors.forename: David J
authors.initials: DJ
authors.lastname: Studholme
mesh_terms: D019295:Computational Biology / Q000379:methods*; D020869:Gene Expression Profiling; D053263:Gene Regulatory Networks / Q000235:genetics; D059014:High-Throughput Nucleotide Sequencing / Q000379:methods*; D010944:Plants / Q000235:genetics*; D018749:RNA, Plant / Q000145:classification / Q000235:genetics*
chemical_list: D018749:RNA, Plant