title: [Unidirectional valved patch for congenital heart  disease with severe pulmonary hypertension].
abstract: OBJECTIVE
  To explore the effect of unidirectional valved patch (UVP) for congenital heart disease (CHD) with severe pulmonary hypertension (PH).
  
  
  METHODS
  We retrospectively analyzed the treatment of 37 CHD patients with severe PH by UVP in the operation, and summarized its short-term to mid-term effect to find an optimum therapeutic regimen.
  
  
  RESULTS
  Before the operation, the ECG showed that the mean pulmonary artery pressure (MPAP) ranged 65-72 mmHg, and the cardiac catheterization showed the pulmonary artery pressure ranged 80-120 mmHg, P(P)/P(A) ranged 0.8-1.05,PVR ranged 8.5-19.2 (under oxygen inhalation 6.8-14.6) wood unit.After the operation, P(P)/P(A) ranged 0.4-0.72 on weaning-off CPB. Postoperative ECG showed the MPAP ranged 32-48 mmHg. No pulmonary hypertension crisis occurred and no patient died. Mechanical ventilation time ranged from 32 h to 8 d and the SaO₂ ranged 93%-96% at rest after the extubation.The right-to-left shunt situations by ECG were as follows:22 cases had shunt 5 d after the operation, 11 cases had shunt 1 month after the operation,4 cases 3 months after the operation, and none 1 year after the operation but one patient lost follow-up.However,there were no long-term follow-up data: 12 patients had a 1-year follow-up, 5 patients had a 3-year follow-up, and most patients had just 3-month follow-up.
  
  
  CONCLUSIONS
  UVP can decrease the operative risk in CHD with severe PH at perioperative period. The short-term to mid-term effect is satisfactory, while long-term effect remains uncertain.
authors.affiliation: Department of Cardiothoracic Surgery, Second Xiangya Hospital,  Central South University, Changsha 410011, China.
authors.forename: Ming
authors.initials: M
authors.lastname: Wu
authors.forename: Jinfu
authors.initials: J
authors.lastname: Yang
authors.forename: Yifeng
authors.initials: Y
authors.lastname: Yang
authors.forename: Jianguo
authors.initials: J
authors.lastname: Hu
authors.forename: Xinmin
authors.initials: X
authors.lastname: Zhou
authors.forename: Feng
authors.initials: F
authors.lastname: Liu
authors.forename: Zhongshi
authors.initials: Z
authors.lastname: Wu
authors.forename: Tianli
authors.initials: T
authors.lastname: Zhao
authors.forename: Lian
authors.initials: L
authors.lastname: Xiong
authors.forename: Xin
authors.initials: X
authors.lastname: Wang
authors.forename: Ni
authors.initials: N
authors.lastname: Yin
mesh_terms: D000293:Adolescent; D006348:Cardiac Surgical Procedures / Q000379:methods; D002648:Child; D005260:Female; D006330:Heart Defects, Congenital / Q000150:complications / Q000601:surgery; D006345:Heart Septal Defects, Ventricular / Q000150:complications / Q000601:surgery*; D006801:Humans; D006976:Hypertension, Pulmonary / Q000209:etiology / Q000601:surgery*; D008297:Male; D010496:Pericardium / Q000637:transplantation*; D019919:Prosthesis Implantation; D012189:Retrospective Studies; D055815:Young Adult