title: FDG-PET findings in fronto-temporal dementia: A case report and review of literature.
abstract: Fronto-temporal lobar degeneration (FTLD) is a clinically and pathologically heterogeneous syndrome, characterized by progressive decline in behavior or language associated with degeneration of the frontal and anterior temporal lobes. Three distinct clinical variants of FTLD have been described. Despite the difficulties, accurate diagnosis is critical because the clinical management differs for Alzheimer's disease (AD) and FTLD. Positron emission tomography with fluro-deoxy-glucose (FDG-PET) typically shows sufficient abnormalities that can be used to improve the accuracy of distinguishing AD from FTLD in individual cases. Though temporo-parietal hypometabolism is sensitive in diagnosis of AD, it is less specific. The importance of evaluating the cingulate and anterior temporal cortices for arriving at a diagnosis of FTLD is stressed.
authors.affiliation: Department of Nuclear Medicine and PET, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
authors.forename: Chidambaram Natrajan Balasubramanian
authors.initials: CN
authors.lastname: Harisankar
authors.forename: Bhagwant Rai
authors.initials: BR
authors.lastname: Mittal
authors.forename: Kanhaiya Lal
authors.initials: KL
authors.lastname: Agrawal
authors.forename: Mohammed Labeeb
authors.initials: ML
authors.lastname: Abrar
authors.forename: Anish
authors.initials: A
authors.lastname: Bhattacharya
authors.forename: Baljinder
authors.initials: B
authors.lastname: Singh
authors.forename: Manish
authors.initials: M
authors.lastname: Modi