title: Cardiac surgery in patients with acute intermittent porphyria.
abstract: Acute intermittent porphyria (AIP) is a disorder of the heme biosynthesis pathway of a specific inherited enzymatic defect. Many different environmental factors such as drugs, calorie restriction, infection etc., often play a key role in triggering a porphiric acute attack. We describe a 50-year-old woman with AIP who underwent aortic valve replacement due to acute infective endocarditis and review the perioperative management of these patients.
authors.affiliation: Department of Cardiovascular Surgery, Hesperia Hospital, Modena, Italy. filippo.benassi@libero.it
authors.forename: Filippo
authors.initials: F
authors.lastname: Benassi
authors.forename: Elena
authors.initials: E
authors.lastname: Righi
authors.forename: Paolo
authors.initials: P
authors.lastname: Cimato
authors.forename: Roberto
authors.initials: R
authors.lastname: Parravicini
mesh_terms: D001022:Aortic Valve Insufficiency / Q000382:microbiology / Q000601:surgery*; D004697:Endocarditis, Bacterial / Q000150:complications / Q000175:diagnosis*; D005260:Female; D019918:Heart Valve Prosthesis Implantation; D006801:Humans; D008875:Middle Aged; D017118:Porphyria, Acute Intermittent / Q000150:complications*; D013203:Staphylococcal Infections / Q000150:complications / Q000175:diagnosis*; D041181:Staphylococcus hominis / Q000302:isolation & purification*