title: Acceptability of self-collected human papillomavirus specimens as a primary screen for cervical cancer.
abstract: The aim of this study was to compare the acceptability of self-collected vs clinician-collected human papillomavirus (HPV) tests. Utilising a cross-sectional approach, 250 non-pregnant, 25-60-year-old women from Leon, Nicaragua self-collected vaginal swabs and brushes for HPV and received a pelvic examination for liquid-based cytology and reflex HPV. Subjects underwent colposcopy, with biopsy if indicated, and completed questionnaires comparing their perceptions of HPV testing methods. Acceptability indices were significantly higher for self-collected brushes (M = 18.40, SD = 2.73) and swabs (M = 18.48, SD = 2.41) than clinician-collection (M = 17.56, SD = 2.92), p < 0.001. Multiple regression analyses revealed that age, education, and reproductive history were not significant predictors of acceptability. A total of 81.1% of subjects reported they would self-collect in the future. Self-collected HPV tests are highly acceptable in terms of pain, comfort, privacy and embarrassment, and are thus a viable method of screening in low-resource areas.
authors.affiliation: Department of Physician Assistant Studies, Elon University, Elon, NC, USA. bquincy@elon.edu
authors.forename: B L
authors.initials: BL
authors.lastname: Quincy
authors.forename: D J
authors.initials: DJ
authors.lastname: Turbow
authors.forename: L N
authors.initials: LN
authors.lastname: Dabinett
mesh_terms: D000328:Adult; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008875:Middle Aged; D030361:Papillomavirus Infections / Q000175:diagnosis*; D010342:Patient Acceptance of Health Care; D012648:Self Care / Q000706:statistics & numerical data*; D013048:Specimen Handling / Q000009:adverse effects / Q000706:statistics & numerical data*; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis*; D014626:Vaginal Smears / Q000523:psychology*