title: Roles of cell volume in molecular and cellular biology.
abstract: Extracellular tonicity and volume regulation control a great number of molecular and cellular functions including: cell proliferation, apoptosis, migration, hormone and neuromediator release, gene expression, ion channel and transporter activity and metabolism. The aim of this review is to describe these effects and to determine if they are direct or are secondarily the result of the activity of second messengers.
authors.affiliation: CNRS, Institut de Neurobiologie Alfred Fessard-FRC2118, Gif sur Yvette F-91198, France. jmdubois@nbcm.cnrs-gif.fr
authors.forename: Jean-Marc
authors.initials: JM
authors.lastname: Dubois
authors.forename: Béatrice
authors.initials: B
authors.lastname: Rouzaire-Dubois
mesh_terms: D000818:Animals; D017209:Apoptosis; D002465:Cell Movement; D049109:Cell Proliferation; D048429:Cell Size; D002477:Cells / Q000166:cytology* / Q000378:metabolism; D005786:Gene Expression Regulation; D006801:Humans