title: Prevention and management of non-steroidal anti-inflammatory drugs-induced small intestinal injury.
abstract: Non-steroidal anti-inflammatory drug (NSAID)-induced small bowel injury is a topic that deserves attention since the advent of capsule endoscopy and balloon enteroscopy. NSAID enteropathy is common and is mostly asymptomatic. However, massive bleeding, stricture, or perforation may occur. The pathogenesis of small intestine injury by NSAIDs is complex and different from that of the upper gastrointestinal tract. No drug has yet been developed that can completely prevent or treat NSAID enteropathy. Therefore, a long-term randomized study in chronic NSAID users is needed.
authors.forename: Sung Chul
authors.initials: SC
authors.lastname: Park
authors.forename: Hoon Jai
authors.initials: HJ
authors.lastname: Chun
authors.forename: Chang Don
authors.initials: CD
authors.lastname: Kang
authors.forename: Donggeun
authors.initials: D
authors.lastname: Sul
mesh_terms: D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects*; D053704:Capsule Endoscopy / Q000295:instrumentation / Q000379:methods; D003937:Diagnosis, Differential; D006801:Humans; D007410:Intestinal Diseases / Q000139:chemically induced* / Q000473:pathology* / Q000517:prevention & control* / Q000628:therapy; D007421:Intestine, Small / Q000187:drug effects* / Q000473:pathology*; D016032:Randomized Controlled Trials as Topic
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal