title: Simultaneous juvenile idiopathic arthritis and diabetes mellitus type 1 -- a Finnish nationwide study.
abstract: OBJECTIVE
  To describe the occurrence and main clinical and laboratory findings of patients having both juvenile idiopathic arthritis (JIA) and diabetes mellitus type 1 (DM-1) in a period of 30 years.
  
  
  METHODS
  Eighty-two patients having simultaneous JIA and DM-1 were identified in the reimbursement registers of the Finnish National Institute of Insurance during the period 1976-2005. Data on their clinical histories were collected from patient files.
  
  
  RESULTS
  Occurrence of simultaneous JIA and DM-1 increased 4.5-fold between the first (1976-85) and the last (1996-2005) decade. Prevalence of uveitis was 7%, of rheumatoid factor seropositivity 15%; 22% of patients had a third autoimmune disease [autoimmune disease (AID)], and 16% had serious psychiatric problems.
  
  
  CONCLUSIONS
  The occurrence of patients with the 2 diseases, JIA and DM-1, increased over 3 decades. The prevalence of uveitis was low, the number of seropositive patients was high, and further cases of AID were frequent. Patients had multiple additional problems necessitating multiprofessional care.
authors.affiliation: Department of Pediatrics, Päijät-Häme District Central Hospital, Lahti, Finland. heini.pohjankoski@phsotey.fi
authors.forename: Heini
authors.initials: H
authors.lastname: Pohjankoski
authors.forename: Hannu
authors.initials: H
authors.lastname: Kautiainen
authors.forename: Matti
authors.initials: M
authors.lastname: Korppi
authors.forename: Anneli
authors.initials: A
authors.lastname: Savolainen
mesh_terms: D000293:Adolescent; D017668:Age of Onset; D001171:Arthritis, Juvenile / Q000453:epidemiology*; D001327:Autoimmune Diseases / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D003922:Diabetes Mellitus, Type 1 / Q000453:epidemiology*; D005260:Female; D005387:Finland / Q000453:epidemiology; D006801:Humans; D008297:Male; D001523:Mental Disorders / Q000453:epidemiology; D015995:Prevalence; D012217:Rheumatoid Factor / Q000097:blood; D014605:Uveitis / Q000188:drug therapy
chemical_list: D012217:Rheumatoid Factor