title: Ammonium molybdophosphate impregnated alumina microspheres as a new generation sorbent for chromatographic 137Cs/(137m)Ba generator.
abstract: Barium-137m availed from a (137)Cs/(137m)Ba generator is an attractive industrial radiotracer for liquid flow rate measurement owing to its short half-life (T(1/2)=2.5 min) and emission of highly energetic gamma radiation (E(γ)=661.7 keV). Ammonium molybdophosphate (AMP) impregnated alumina microspheres (AMP-Al(2)O(3)), an engineered form of sorbent material was synthesized by Gel Entrapment Technique (GET). The utility of the material in the preparation of (137)Cs/(137m)Ba generator was evaluated. Various experimental parameters were optimized for efficient retention of (137)Cs and selective elution of (137m)Ba. A chromatographic 0.74 GBq (20 mCi) (137)Cs/(137m)Ba generator was developed using this material and its performance was evaluated for 6 months. Barium-137m could be eluted from the generator using 0.1 M NH(4)NO(3)+0.5 M HNO(3) solution with >80% yield and with acceptable radionuclidic purity suitable for industrial radiotracer investigations.
authors.affiliation: Radiopharmaceuticals Division, Bhabha Atomic Research Centre, Mumbai 400085, India.
authors.forename: Rubel
authors.initials: R
authors.lastname: Chakravarty
authors.forename: Ramu
authors.initials: R
authors.lastname: Ram
authors.forename: K T
authors.initials: KT
authors.lastname: Pillai
authors.forename: Yugandhara
authors.initials: Y
authors.lastname: Pamale
authors.forename: R V
authors.initials: RV
authors.lastname: Kamat
authors.forename: Ashutosh
authors.initials: A
authors.lastname: Dash
mesh_terms: D000327:Adsorption; D000537:Aluminum Oxide / Q000737:chemistry*; D001465:Barium Radioisotopes / Q000737:chemistry*; D002588:Cesium Radioisotopes / Q000737:chemistry*; D002853:Chromatography, Liquid / Q000295:instrumentation*; D004867:Equipment Design; D008863:Microspheres; D008982:Molybdenum / Q000737:chemistry*; D010756:Phosphoric Acids / Q000737:chemistry*; D011849:Radioactive Tracers; D011876:Radionuclide Generators / Q000295:instrumentation*
chemical_list: D001465:Barium Radioisotopes; D002588:Cesium Radioisotopes; D010756:Phosphoric Acids; D011849:Radioactive Tracers; D008982:Molybdenum; D000537:Aluminum Oxide; C003125:phosphomolybdic acid