title: Role of high-intensity focused ultrasound in treatment of hepatocellular carcinoma.
abstract: About 70 per cent of patients with hepatocellular carcinoma are diagnosed at intermediate or advanced stages, and most of them are technically unresectable. As a novel, emerging therapeutic modality, high intensity focused ultrasound (HIFU) has a great potential for tumor treatment.  In this review, principle of HIFU technique is introduced, and an overview of clinical applications and limitations of HIFU for HCC treatment, as well as prospects for future development, is provided. Consequently, HIFU has been considered a safe and feasible procedure for HCC treatment.
authors.affiliation: Department of Hepatobiliary Surgery, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
authors.forename: Hua-Ping
authors.initials: HP
authors.lastname: Shen
authors.forename: Jian-Ping
authors.initials: JP
authors.lastname: Gong
authors.forename: Guo-Qing
authors.initials: GQ
authors.lastname: Zuo
mesh_terms: D006528:Carcinoma, Hepatocellular / Q000473:pathology / Q000601:surgery*; D005240:Feasibility Studies; D006801:Humans; D008113:Liver Neoplasms / Q000473:pathology / Q000601:surgery*; D009364:Neoplasm Recurrence, Local / Q000517:prevention & control; D009367:Neoplasm Staging; D016896:Treatment Outcome; D059708:Ultrasonic Surgical Procedures / Q000379:methods*