title: Factors associated with hospital admission for exacerbation of chronic obstructive pulmonary disease.
abstract: BACKGROUND
  Exacerbations of Chronic Obstructive Pulmonary Disease (COPD) that require hospital admission have a major impact on the progression of disease and generate high health costs.
  
  
  METHODS
  A multi-center, cross-sectional, observational, study was conducted with the aim to identify factors associated with hospital admission in patients with COPD. We obtained data of socio-demographic and anthropometric characteristics, quality of life, respiratory symptoms, anxiety and depression, physical activity and pulmonary function tests. We analyzed their association with hospital admission with a multivariate analysis using a logistic regression model.
  
  
  RESULTS
  We analyzed 127 patients, 50 (39%) of whom had been hospitalized. 93.7% were men, mean age 67 years (SD=9) and a FEV1 of 41.9% (SD=15.3). In the first model obtained, the baseline SpO(2), the BODE index and emergency room (ER) visits were associated with hospital admission and the area under the ROC curve (AUC) was 0.809. In a second model we included only variables readily available (without the 6 minutes walking test) and only the SpO(2) and previous visits to the ER were significant with an AUC ROC 0.783.
  
  
  CONCLUSIONS
  hospital admission for exacerbation of COPD is associated with poor SpO(2), higher BODE index score and a greater number of visits to the ER. In case you do not have the 6 minutes walking test, the other two variables offer a similar discriminative ability.
authors.affiliation: Unidad de Gestión Clínica de Neumología, Complejo Hospitalario de Jaén, Spain. balcazar@telefonica.net
authors.forename: Bernardino
authors.initials: B
authors.lastname: Alcázar
authors.forename: Cayo
authors.initials: C
authors.lastname: García-Polo
authors.forename: Alberto
authors.initials: A
authors.lastname: Herrejón
authors.forename: Luis Alberto
authors.initials: LA
authors.lastname: Ruiz
authors.forename: Javier
authors.initials: J
authors.lastname: de Miguel
authors.forename: José Antonio
authors.initials: JA
authors.lastname: Ros
authors.forename: Patricia
authors.initials: P
authors.lastname: García-Sidro
authors.forename: Gema Tirado
authors.initials: GT
authors.lastname: Conde
authors.forename: José Luis
authors.initials: JL
authors.lastname: López-Campos
authors.forename: Carlos
authors.initials: C
authors.lastname: Martínez
authors.forename: Joaquin
authors.initials: J
authors.lastname: Costán
authors.forename: Marc
authors.initials: M
authors.lastname: Bonnin
authors.forename: Sagrario
authors.initials: S
authors.lastname: Mayoralas
authors.forename: Marc
authors.initials: M
authors.lastname: Miravitlles
mesh_terms: D000328:Adult; D000368:Aged; D001007:Anxiety / Q000453:epidemiology; D019540:Area Under Curve; D003430:Cross-Sectional Studies; D003863:Depression / Q000453:epidemiology; D004636:Emergency Service, Hospital / Q000706:statistics & numerical data; D005080:Exercise Test; D005260:Female; D006334:Heart Function Tests; D006801:Humans; D008297:Male; D008875:Middle Aged; D010100:Oxygen / Q000097:blood; D010343:Patient Admission / Q000706:statistics & numerical data; D029424:Pulmonary Disease, Chronic Obstructive / Q000188:drug therapy / Q000453:epidemiology* / Q000503:physiopathology / Q000523:psychology / Q000628:therapy; D012129:Respiratory Function Tests; D012307:Risk Factors; D012720:Severity of Illness Index; D012907:Smoking / Q000453:epidemiology; D012959:Socioeconomic Factors; D013030:Spain / Q000453:epidemiology
chemical_list: D010100:Oxygen