title: The hematopoietic cell transplantation comorbidity index is a predictor of early death and survival in adult acute myeloid leukemia patients.
abstract: The hematopoietic cell transplantation comorbidity index (HCT-CI) is predictive of early death and survival in elderly patients with acute myeloid leukemia (AML). The aim of this study was to determine the prognostic role of the HCT-CI for early death and survival in adult AML patients. In the single-center retrospective study, we analyzed the outcome of 233 adult AML patients. The results indicated that the HCT-CI score is an independent predictor of early death in entire cohort of adult patients with AML. In subgroup analysis, HCT-CI is an independent predictor for early death in elderly patients but not in patients younger than 60 years. A high HCT-CI score predicts shorter survival in adult patients with AML.
authors.affiliation: Clinic of Hematology, Clinical Center of Vojvodina, Novi Sad, Serbia. asavic@uns.ac.rs
authors.forename: Aleksandar
authors.initials: A
authors.lastname: Savic
authors.forename: Vanja
authors.initials: V
authors.lastname: Kvrgic
authors.forename: Nebojsa
authors.initials: N
authors.lastname: Rajic
authors.forename: Ivana
authors.initials: I
authors.lastname: Urosevic
authors.forename: Dragan
authors.initials: D
authors.lastname: Kovacevic
authors.forename: Ivanka
authors.initials: I
authors.lastname: Percic
authors.forename: Stevan
authors.initials: S
authors.lastname: Popovic
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015897:Comorbidity; D005260:Female; D018380:Hematopoietic Stem Cell Transplantation / Q000401:mortality*; D006801:Humans; D053208:Kaplan-Meier Estimate; D015470:Leukemia, Myeloid, Acute / Q000401:mortality* / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D016016:Proportional Hazards Models; D012189:Retrospective Studies; D055815:Young Adult