title: Highly Enantioselective Asymmetric Darzens Reactions with a Phase Transfer Catalyst.
abstract: A class of easily accessible and readily tunable chiral phase transfer catalysts based on 6'-OH cinchonium salts was found to efficiently catalyze an unprecedented highly enantioselective Darzens reaction of α-chloro ketones and aldehydes, which directly produces optically active chiral epoxides from readily available carbonyl compounds.
authors.affiliation: Department of Chemistry, Brandeis University, Waltham, Massachusetts, 02454, USA.
authors.forename: Yan
authors.initials: Y
authors.lastname: Liu
authors.forename: Brian A
authors.initials: BA
authors.lastname: Provencher
authors.forename: Keith J
authors.initials: KJ
authors.lastname: Bartleson
authors.forename: Li
authors.initials: L
authors.lastname: Deng