title: Hexafluorobenzene: a powerful solvent for a noncovalent stereoselective organocatalytic Michael addition reaction.
abstract: A dramatic enhancement of the diastereo- and enantioselectivity in the nitro-Michael addition reaction organocatalysed by a commercially available α,α-L-diaryl prolinol was disclosed when performing the reaction in unconventional hexafluorobenzene as a medium. DFT calculations were performed to clarify the origin of stereoselectivity and the role of C(6)F(6).
authors.affiliation: Dipartimento di Chimica e Biologia, Via Ponte don Melillo, 84084, Fisciano, Italy. lattanzi@unisa.it
authors.forename: Alessandra
authors.initials: A
authors.lastname: Lattanzi
authors.forename: Claudia
authors.initials: C
authors.lastname: De Fusco
authors.forename: Alessio
authors.initials: A
authors.lastname: Russo
authors.forename: Albert
authors.initials: A
authors.lastname: Poater
authors.forename: Luigi
authors.initials: L
authors.lastname: Cavallo