title: Gene augmentation trials using the Rpe65-deficient dog: contributions towards development and refinement of human clinical trials.
authors.affiliation: Department of Small Animal Clinical Sciences, Michigan State University, East Lansing, MI 48824, USA. peter315@cvm.msu.edu
authors.forename: Simon M
authors.initials: SM
authors.lastname: Petersen-Jones
authors.forename: Matthew J
authors.initials: MJ
authors.lastname: Annear
authors.forename: Joshua T
authors.initials: JT
authors.lastname: Bartoe
authors.forename: Freya M
authors.initials: FM
authors.lastname: Mowat
authors.forename: Susie E
authors.initials: SE
authors.lastname: Barker
authors.forename: Alexander J
authors.initials: AJ
authors.lastname: Smith
authors.forename: James W
authors.initials: JW
authors.lastname: Bainbridge
authors.forename: Robin R
authors.initials: RR
authors.lastname: Ali
mesh_terms: D000818:Animals; D002352:Carrier Proteins / Q000235:genetics*; D017321:Clinical Trials, Phase I as Topic / Q000379:methods; D017322:Clinical Trials, Phase II as Topic / Q000379:methods; D004195:Disease Models, Animal; D004285:Dogs; D005136:Eye Proteins / Q000235:genetics*; D015316:Genetic Therapy / Q000379:methods*; D006801:Humans; D057130:Leber Congenital Amaurosis / Q000235:genetics* / Q000276:immunology / Q000628:therapy*; D019745:cis-trans-Isomerases; D000099178:Retinoid Isomerohydrolase
chemical_list: D002352:Carrier Proteins; D005136:Eye Proteins; D019745:cis-trans-Isomerases; D000099178:Retinoid Isomerohydrolase