title: "Boldness be my friend" (Shakespeare; Cymbeline).
abstract: Au et al report in this issue of Blood that oral arsenic trioxide (ATO) may be safely used in maintenance therapy in acute promyelocytic leukemia (APL). This is a major improvement in convenience given that intravenous (IV)ATO requires daily administration for weeks at a time. In addition, the oral formulation may be less toxic. The time seems right to carefully explore the introduction of oral ATO earlier in treatment of the disease.
authors.affiliation: Robert H. Lurie Comprehensive Cancer Center; Memorial Sloan-Kettering Cancer Center.
authors.forename: Jessica K
authors.initials: JK
authors.lastname: Altman
authors.forename: Martin S
authors.initials: MS
authors.lastname: Tallman