title: Paroxysmal nocturnal hemoglobinuria presenting with a left intraventricular thrombus in a patient with prior thymoma and aplastic anemia.
abstract: We report the case of a 37-year old man presenting with a left ventricular cardiac thrombus in the setting of subclinical paroxysmal nocturnal hemoglobinura (PNH) developing two years after immunosuppressive therapy for thymoma-associated aplastic anemia. The literature regarding the interplay between autoimmunity and immunosuppression, aplastic anemia, thymoma and the emergence of PNH is reviewed.
authors.affiliation: Division of Hematology and Oncology, Memorial Hospital of Rhode Island, Alpert Medical School of Brown University, Providence, RI, United States of America.
authors.forename: Yazan
authors.initials: Y
authors.lastname: Migdady
authors.forename: Adam J
authors.initials: AJ
authors.lastname: Olszewski