title: The number of women who would need to be screened regularly by mammography to prevent one death from breast cancer.
abstract: The number of women who would need to be screened regularly by mammography to prevent one death from breast cancer depends strongly on several factors, including the age at which regular screening starts, the period over which it continues, and the duration of follow-up after screening. Furthermore, more women would need to be INVITED for screening than would need to be SCREENED to prevent one death, since not all women invited attend for screening or are screened regularly. Failure to consider these important factors accounts for many of the major discrepancies between different published estimates. The randomised evidence indicates that, in high income countries, around one breast cancer death would be prevented in the long term for every 400 women aged 50-70 years regularly screened over a ten-year period.
authors.affiliation: University of Oxford, UK. pa.valerie.beral@ceu.ox.ac.uk
authors.forename: Valerie
authors.initials: V
authors.lastname: Beral
authors.forename: Maggie
authors.initials: M
authors.lastname: Alexander
authors.forename: Stephen
authors.initials: S
authors.lastname: Duffy
authors.forename: Ian O
authors.initials: IO
authors.lastname: Ellis
authors.forename: Rosalind
authors.initials: R
authors.lastname: Given-Wilson
authors.forename: Lars
authors.initials: L
authors.lastname: Holmberg
authors.forename: Sue M
authors.initials: SM
authors.lastname: Moss
authors.forename: Amanda
authors.initials: A
authors.lastname: Ramirez
authors.forename: Malcolm W R
authors.initials: MW
authors.lastname: Reed
authors.forename: Caroline
authors.initials: C
authors.lastname: Rubin
authors.forename: Patsy
authors.initials: P
authors.lastname: Whelehan
authors.forename: Robin
authors.initials: R
authors.lastname: Wilson
authors.forename: Kenneth C
authors.initials: KC
authors.lastname: Young
mesh_terms: D000368:Aged; D001943:Breast Neoplasms / Q000401:mortality* / Q000517:prevention & control*; D019049:Developed Countries; D005260:Female; D006801:Humans; D008327:Mammography / Q000706:statistics & numerical data; D008403:Mass Screening / Q000706:statistics & numerical data; D008875:Middle Aged; D006113:United Kingdom