title: Effect of phosphorus dendrimers on DMPC lipid membranes.
abstract: Large unilamellar liposomes and multilamellar vesicles consisting of DMPC interacted with cationic phosphorus-containing dendrimers CPDs G3 and G4. DSC and ζ-potential measurements have shown that liposomal-dendrimeric molecular recognition probably occurs due to the interaction between the complementary surface groups. Calorimetric studies indicate that the enthalpy of the transition of the lipids that interact with CPDs is dependent on the dendrimers generation. These results can be used in order to rationally design mixed modulatory liposomal locked-in dendrimeric, drug delivery nano systems.
authors.affiliation: Department of General Biophysics, University of Lodz, Banacha 12/16, 90-237 Lodz, Poland. maksion@biol.uni.lodz.pl
authors.forename: Maksim
authors.initials: M
authors.lastname: Ionov
authors.forename: Dominika
authors.initials: D
authors.lastname: Wróbel
authors.forename: Konstantinos
authors.initials: K
authors.lastname: Gardikis
authors.forename: Sophia
authors.initials: S
authors.lastname: Hatziantoniou
authors.forename: Costas
authors.initials: C
authors.lastname: Demetzos
authors.forename: Jean-Pierre
authors.initials: JP
authors.lastname: Majoral
authors.forename: Barbara
authors.initials: B
authors.lastname: Klajnert
authors.forename: Maria
authors.initials: M
authors.lastname: Bryszewska
mesh_terms: D002152:Calorimetry, Differential Scanning; D002412:Cations / Q000737:chemistry; D050091:Dendrimers / Q000737:chemistry*; D004134:Dimyristoylphosphatidylcholine / Q000737:chemistry*; D004337:Drug Carriers / Q000737:chemistry; D008081:Liposomes / Q000737:chemistry*; D010316:Particle Size; D010758:Phosphorus / Q000737:chemistry*; D013816:Thermodynamics
chemical_list: D002412:Cations; D050091:Dendrimers; D004337:Drug Carriers; D008081:Liposomes; D010758:Phosphorus; D004134:Dimyristoylphosphatidylcholine