title: The relationship between basal and squamous cell skin cancer and smoking related cancers.
abstract: BACKGROUND
  We compared the risk of being diagnosed with smoking-related cancers (lung, oral cavity, upper digestive and respiratory organs, bladder, kidney, anogenital cancers and myeloid leukaemia) among people with squamous cell carcinoma (SCC) or basal cell carcinoma of the skin (BCC), with risks found in the general population using data from an Australian population-based cancer registry.
  
  
  METHODS
  People diagnosed with BCC or SCC in 1980-2003 reported to the Tasmanian Cancer Registry, Australia, were followed-up by linkage within the registry, until diagnosis of a subsequent smoking-related cancer, death, or until 31 December 2003. Risk of developing a future smoking-related cancer was assessed using age Standardised Incidence Ratios (SIR).
  
  
  RESULTS
  People diagnosed with SCC had an increased risk of lung cancer (men: SIR = 1.89, 95% confidence interval: 1.61-2.21; women: SIR = 2.04, 1.42-2.83) and all other smoking-related cancers (men: SIR = 1.38, 1.19-1.60; women: SIR = 1.78, 1.34-2.33). Men with BCC had a significant increased risk of lung cancer (SIR = 1.26, 1.10-1.44) but not of any of the other smoking-related cancers (SIR = 1.09, 0.97-1.23).
  
  
  CONCLUSIONS
  Individuals with a history of SCC having an increased risk of developing smoking related cancers cancer suggests smoking as a common etiology. The relationship between BCC and smoking-related cancers is less certain.
authors.affiliation: Cancer Research Division, Cancer Council New South Wales, Sydney, Australia. freddys@nswcc.org.au.
authors.forename: Freddy
authors.initials: F
authors.lastname: Sitas
authors.forename: Xue Qin
authors.initials: XQ
authors.lastname: Yu
authors.forename: Dianne L
authors.initials: DL
authors.lastname: O'Connell
authors.forename: Leigh
authors.initials: L
authors.lastname: Blizzard
authors.forename: Petr
authors.initials: P
authors.lastname: Otahal
authors.forename: Leah
authors.initials: L
authors.lastname: Newman
authors.forename: Alison
authors.initials: A
authors.lastname: Venn