title: [Association of anemia with cognition among senior female in China].
abstract: OBJECTIVE
  To explore the relationship between anemia and cognitive function among senior female aged 90 years old and above in longevity regions in China.
  
  
  METHODS
  383 senior female in 5 longevity areas from the Chinese Longitudinal Healthy Longevity Survey (CLHLS) 2008 - 2009 were included in the study. The cognitive function was assessed by mini mental state examination (MMSE) scale. All subjects were administered the physical examinations and biochemical testing of blood, including the hemoglobin. The difference of cognitive function between those with and without anemia was analyzed. Logistic regression was used to analyze the relationship between anemia and cognitive function.
  
  
  RESULTS
  The 383 subjects were divided into two groups, 141 in anemia group and 242 in group without anemia. The total score of cognitive function was 9.65 ± 9.32 in anemia group, and 13.06 ± 10.25 in group without anemia (χ(2) = 5.59, P < 0.05). The percentage of cognition impairment was 84.4% (119/141) in anemia group, and 72.3% (175/242) in group without anemia (χ(2) = 8.08, P < 0.05). In the multivariable logistic regressions, after adjustment for age, education, marital status, smoking and alcohol drinking, the risk for cognition impairment in anemia group was about twice of that in group without anemia (OR = 2.016, 95%CI: 1.185 - 3.431, P = 0.010).
  
  
  CONCLUSIONS
  Anemia increases the risk of cognition impairment among senior female in Chinese longevity areas.
authors.affiliation: Division of Chronic Diseases Control and Community Health, Chinese Center for Disease Control and Prevention, Beijing.
authors.forename: Yi
authors.initials: Y
authors.lastname: Zhai
authors.forename: Xiao-Ming
authors.initials: XM
authors.lastname: Shi
authors.forename: Han-Zhu
authors.initials: HZ
authors.lastname: Qian
authors.forename: Simon Michael
authors.initials: SM
authors.lastname: Fitzgerald
authors.forename: Yi
authors.initials: Y
authors.lastname: Zeng
authors.forename: Zhao-Xue
authors.initials: ZX
authors.lastname: Yin
authors.forename: Jian-Wei
authors.initials: JW
authors.lastname: Xu
authors.forename: Yu-Zhi
authors.initials: YZ
authors.lastname: Liu
mesh_terms: D000367:Age Factors; D000369:Aged, 80 and over; D000740:Anemia / Q000453:epidemiology / Q000523:psychology*; D015984:Causality; D002681:China / Q000453:epidemiology; D003071:Cognition; D005260:Female; D006801:Humans; D008136:Longevity