title: Sulcus  vocalis: evidence for autosomal dominant inheritance.
abstract: We  found evidence of autosomal dominant hereditary transmission of sulcus vocalis.  Four dysphonic patients from three generations of the same family were  submitted to videolaryngoscopic examination (three patients) and to direct laryngoscopy  (one patient) to diagnose the hoarseness. Sulcus vocalis was diagnosed in all  four patients. The finding of four affected individuals in three generations,  with vertical transmission affecting man and women, is more consistent with  autosomal dominant inheritance pattern; it is an etiological model that we  propose for the sulcus vocalis in this pedigree.
authors.affiliation: Departamento de Otorrinolaringologia, Faculdade de Medicina de Botucatu, Universidade Estadual de São Paulo Júlio de Mesquita Filho, Botucatu, SP, Brasil.
authors.forename: R H G
authors.initials: RH
authors.lastname: Martins
authors.forename: T M
authors.initials: TM
authors.lastname: Gonçalves
authors.forename: D S
authors.initials: DS
authors.lastname: Neves
authors.forename: T A
authors.initials: TA
authors.lastname: Fracalossi
authors.forename: E L M
authors.initials: EL
authors.lastname: Tavares
authors.forename: D
authors.initials: D
authors.lastname: Moretti-Ferreira
mesh_terms: D000328:Adult; D001938:Brazil; D002648:Child; D002675:Child, Preschool; D005260:Female; D005799:Genes, Dominant; D006685:Hoarseness / Q000235:genetics* / Q000503:physiopathology; D006801:Humans; D007828:Laryngoscopy; D008297:Male; D008875:Middle Aged; D010375:Pedigree; D010641:Phenotype; D014827:Vocal Cords / Q000002:abnormalities* / Q000503:physiopathology