title: Oscillatory sensory selection mechanisms during intersensory attention to rhythmic auditory and visual inputs: a human electrocorticographic investigation.
abstract: Oscillatory entrainment mechanisms are invoked during attentional processing of rhythmically occurring stimuli, whereby their phase alignment regulates the excitability state of neurons coding for anticipated inputs. These mechanisms have been examined in the delta band (1-3 Hz), where entrainment frequency matches the stimulation rate. Here, we investigated entrainment for subdelta rhythmic stimulation, recording from intracranial electrodes over human auditory cortex during an intersensory audiovisual task. Audiovisual stimuli were presented at 0.67 Hz while participants detected targets within one sensory stream and ignored the other. It was found that entrainment operated at twice the stimulation rate (1.33 Hz), and this was reflected by higher amplitude values in the FFT spectrum, cyclic modulation of alpha-amplitude, and phase-amplitude coupling between delta phase and alpha power. In addition, we found that alpha-amplitude was relatively increased in auditory cortex coincident with to-be-ignored auditory stimuli during attention to vision. Thus, the data suggest that entrainment mechanisms operate within a delimited passband such that for subdelta task rhythms, oscillatory harmonics are invoked. The phase of these delta-entrained oscillations modulates alpha-band power. This may in turn increase or decrease responsiveness to relevant and irrelevant stimuli, respectively.
authors.affiliation: The Cognitive Neurophysiology Laboratory, Nathan S. Kline Institute for Psychiatric Research, Program in Cognitive Neuroscience and Schizophrenia, Orangeburg, New York 10962, USA.
authors.forename: Manuel
authors.initials: M
authors.lastname: Gomez-Ramirez
authors.forename: Simon P
authors.initials: SP
authors.lastname: Kelly
authors.forename: Sophie
authors.initials: S
authors.lastname: Molholm
authors.forename: Pejman
authors.initials: P
authors.lastname: Sehatpour
authors.forename: Theodore H
authors.initials: TH
authors.lastname: Schwartz
authors.forename: John J
authors.initials: JJ
authors.lastname: Foxe
mesh_terms: D000161:Acoustic Stimulation; D000328:Adult; D001288:Attention / Q000502:physiology*; D001307:Auditory Perception / Q000502:physiology*; D001931:Brain Mapping; D002540:Cerebral Cortex / Q000502:physiology*; D004569:Electroencephalography; D004827:Epilepsy / Q000503:physiopathology; D005260:Female; D006801:Humans; D008297:Male; D009474:Neurons / Q000502:physiology*; D010507:Periodicity; D010775:Photic Stimulation; D011930:Reaction Time / Q000502:physiology; D014796:Visual Perception / Q000502:physiology*