title: [High-grade fetal adenocarcinoma of the lung; report of a case].
abstract: 82-year-old man was admitted with an abnormal shadow on the chest roentgenogram. Computed tomography showed a 2.8 x 2.4 cm solid tumor in S3 of the left lung. Transbronchial lung biopsy revealed adenocarcinoma and a left upper lobectomy (ND2a-1) was performed. The tumor consisted mainly of tall columnar clear cells, and no morules were found. Immunohistochemically, the tumor was positive for alpha-fetoprotein (AFP) and p53. Accordingly, we made the histological diagnosis of high-grade fetal adenocarcinoma of the lung, pT2N0M0, stage IB. The patient was not received adjuvant therapy and has been doing well without any tumor recurrence for 3 months postoperatively.
authors.affiliation: Department of Thoracic Surgery, Nishigunma National Hospital, Shibukawa, Japan.
authors.forename: Seiichi
authors.initials: S
authors.lastname: Kakegawa
authors.forename: Osamu
authors.initials: O
authors.lastname: Kawashima
authors.forename: Takashi
authors.initials: T
authors.lastname: Ibe
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Tomizawa
authors.forename: Masanori
authors.initials: M
authors.lastname: Iwashina
authors.forename: Masuo
authors.initials: M
authors.lastname: Ujita
authors.forename: Tetsuhiro
authors.initials: T
authors.lastname: Nakano
authors.forename: Toshiteru
authors.initials: T
authors.lastname: Nagashima
authors.forename: Kimihiro
authors.initials: K
authors.lastname: Shimizu
authors.forename: Izumi
authors.initials: I
authors.lastname: Takeyoshi
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology*; D000369:Aged, 80 and over; D006801:Humans; D007150:Immunohistochemistry; D008175:Lung Neoplasms / Q000473:pathology*; D008297:Male; D016159:Tumor Suppressor Protein p53 / Q000032:analysis; D000509:alpha-Fetoproteins / Q000032:analysis
chemical_list: D016159:Tumor Suppressor Protein p53; D000509:alpha-Fetoproteins