title: [Retinal manifestations in patients with sickle cell disease referred to a University Eye Hospital].
abstract: OBJECTIVE
  To identify retinal manifestations in patients with sickle cell disease referred to a reference eye hospital in Goiânia (GO).
  
  
  METHODS
  Ophthalmic evaluation was made in 50 patients (100 eyes) with sickle cell disease to evaluate the most common manifestations of this group.
  
  
  RESULTS
  Hemoglobinopathy SS was the most commonly found, followed by hemoglobin SC, AS and Stahl. Twenty-two percent of the patients had retinal changes, of these 73% were male. Retinal changes observed were: "sea fan", "black sunburst", vitreous hemorrhage, and retinal detachment. In the classification of retinopathy, 73% had proliferative form, seen in the types AS and SC and 27% had non-proliferative retinopathy, seen in patients with SS type.
  
  
  CONCLUSIONS
  We observed a large numbers of patients with retinal changes, most of them with hemoglobinopathy SC, followed by AS and SS groups. The proliferative changes were the most commonly observed. Vitreous hemorrhage and retinal detachment were the most prevalent manifestations in proliferative retinopathy and showed to be more common in patients with SC hemoglobinopathy in the studied population.
authors.affiliation: Departamento de Retina e Vítreo, Centro de Referência em Oftalmologia, Hospital das Clínicas, Universidade Federal de Goiás, Goiânia, Brazil. luizgfreitas@gmail.com
authors.forename: Luiz Guilherme Azevedo de
authors.initials: LG
authors.lastname: Freitas
authors.forename: David Leonardo Cruvinel
authors.initials: DL
authors.lastname: Isaac
authors.forename: William Thomas
authors.initials: WT
authors.lastname: Tannure
authors.forename: Elisa Vieira da Silva
authors.initials: EV
authors.lastname: Lima
authors.forename: Murilo Batista
authors.initials: MB
authors.lastname: Abud
authors.forename: Renato Sampaio
authors.initials: RS
authors.lastname: Tavares
authors.forename: Clovis Arcoverde de
authors.initials: CA
authors.lastname: Freitas
authors.forename: Marcos Pereira de
authors.initials: MP
authors.lastname: Avila
mesh_terms: D000755:Anemia, Sickle Cell / Q000150:complications*; D003430:Cross-Sectional Studies; D005260:Female; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D006801:Humans; D008297:Male; D033401:Microscopy, Acoustic; D009887:Ophthalmoscopy; D012164:Retinal Diseases / Q000175:diagnosis / Q000209:etiology*