title: Isolated mediastinal myeloid sarcoma successfully treated with chemoradiotherapy followed by unrelated allogeneic stem cell transplantation.
abstract: A 22-year-old man was diagnosed with isolated mediastinal myeloid sarcoma which radiologically mimicked primary mediastinal lymphoma. Despite administration of standard remission induction chemotherapy with daunorubicin and cytarabine, and three cycles of intensive high-dose cytarabine-based consolidation, chemo-resistant hypermetabolic lesions were persistently detected in the highest mediastinum and in the supraclavicular area. However, complete remission and long-term survival were achieved by curative radiotherapy followed by unrelated allogeneic stem cell transplantation.
authors.affiliation: Division of Oncology and Hematology Department of Internal Medicine, Gyeongsang National University Hospital, Gyeongsang National University School of Medicine, Korea.
authors.forename: Jeong Mi
authors.initials: JM
authors.lastname: Lee
authors.forename: Haa-Na
authors.initials: HN
authors.lastname: Song
authors.forename: Yeojin
authors.initials: Y
authors.lastname: Kang
authors.forename: Hosu
authors.initials: H
authors.lastname: Kim
authors.forename: Ji Hyun
authors.initials: JH
authors.lastname: Min
authors.forename: Young Sun
authors.initials: YS
authors.lastname: Suh
authors.forename: Jong-Hwa
authors.initials: JH
authors.lastname: Ahn
authors.forename: Seung Hun
authors.initials: SH
authors.lastname: Lee
authors.forename: Yun-Won
authors.initials: YW
authors.lastname: Jo
authors.forename: Yun-Hong
authors.initials: YH
authors.lastname: Cheon
authors.forename: Moon Jin
authors.initials: MJ
authors.lastname: Kim
authors.forename: Gyeong-Won
authors.initials: GW
authors.lastname: Lee
mesh_terms: D059248:Chemoradiotherapy; D003937:Diagnosis, Differential; D006801:Humans; D008223:Lymphoma / Q000175:diagnosis; D008297:Male; D008479:Mediastinal Neoplasms / Q000175:diagnosis / Q000628:therapy*; D036102:Peripheral Blood Stem Cell Transplantation; D023981:Sarcoma, Myeloid / Q000175:diagnosis / Q000628:therapy*; D014184:Transplantation, Homologous; D055815:Young Adult