title: Declining incidence of candidemia in a tertiary inpatient pediatric population.
abstract: We examined the incidence of candidemia, Candida species distribution, and antifungal susceptibility patterns in a pediatric institution. We identified 301 episodes of candidemia from 2001 to 2010 inclusive. Annual incidence decreased from 0.68 to 0.12 cases/1,000 patient days between 2004 and 2010. Candida albicans was the most common species, followed by C. parapsilosis. All isolates tested were susceptible to amphotericin B and caspofungin, but 11% were resistant or dose-dependently susceptible to fluconazole.
authors.affiliation: The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA. otak@email.chop.edu
authors.forename: Kaede V
authors.initials: KV
authors.lastname: Ota
authors.forename: Karin L
authors.initials: KL
authors.lastname: McGowan
mesh_terms: D000293:Adolescent; D000935:Antifungal Agents / Q000494:pharmacology; D002175:Candida / Q000145:classification* / Q000187:drug effects / Q000302:isolation & purification*; D058387:Candidemia / Q000453:epidemiology* / Q000382:microbiology; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D006761:Hospitals; D006801:Humans; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D007297:Inpatients; D008826:Microbial Sensitivity Tests; D012189:Retrospective Studies
chemical_list: D000935:Antifungal Agents