title: On the paradoxical determinations of the lacuno-canalicular permeability of bone.
abstract: The lacuno-canalicular permeability has been shown to play a key role in the behavior of bone tissue. The aim of this study is, by giving an overview of the determinations of this parameter, to question the paradoxical values provided by theoretical predictions and recent experimental measurements. We propose therefore a Kozeny-like law obtained by a numerical method which relates the permeability to the textural parameters of cortical bone microstructure. Moreover, we suggest possible explanations for this paradox considering the empirical difficulties and possible multiphysical effects.
authors.affiliation: Laboratoire Modélisation et Simulation Multi Echelle, MSME UMR 8208 CNRS, Université Paris-Est, 61 Avenue du Général de Gaulle, 94010, Créteil, France. thibault.lemaire@univ-paris-est.fr
authors.forename: T
authors.initials: T
authors.lastname: Lemaire
authors.forename: S
authors.initials: S
authors.lastname: Lemonnier
authors.forename: S
authors.initials: S
authors.lastname: Naili
mesh_terms: D000465:Algorithms; D016880:Anisotropy; D001696:Biomechanical Phenomena; D001842:Bone and Bones / Q000378:metabolism*; D004563:Electrochemistry / Q000379:methods; D020342:Finite Element Analysis; D006801:Humans; D007700:Kinetics; D008954:Models, Biological; D008962:Models, Theoretical; D010011:Osteocytes / Q000502:physiology*; D010539:Permeability; D016062:Porosity; D012984:Software; D014783:Viscosity