title: [Opportunities for effective skin regeneration by topical stimulation of immunity].
abstract: A murine model of incisional wound was used to evaluate effect of topical application of purified bacterial lipopolysaccharide on the wound healing process. Thirty five ICR mice were used in the study. It was shown that bacterial lipopolysaccharide is a strong promotor of wound healing. It increases tensile strength, accelerates completion of the inflammatory process, stimulates collagen deposition and early remodeling.
authors.forename: A V
authors.initials: AV
authors.lastname: Kostarnoĭ
authors.forename: D Iu
authors.initials: DIu
authors.lastname: Logunov
authors.forename: A I
authors.initials: AI
authors.lastname: Tukhvatulin
authors.forename: V A
authors.initials: VA
authors.lastname: Kolesnilova
authors.forename: T P
authors.initials: TP
authors.lastname: Malofeeva
authors.forename: N E
authors.initials: NE
authors.lastname: Filippova
authors.forename: B S
authors.initials: BS
authors.lastname: Naroditskiĭ
mesh_terms: D000287:Administration, Topical; D000818:Animals; D017439:Cicatrix, Hypertrophic / Q000209:etiology / Q000276:immunology / Q000517:prevention & control*; D007113:Immunity, Innate; D007155:Immunologic Factors / Q000008:administration & dosage / Q000276:immunology; D008070:Lipopolysaccharides / Q000008:administration & dosage / Q000276:immunology; D051379:Mice; D012867:Skin / Q000293:injuries; D013718:Tensile Strength / Q000187:drug effects*; D051193:Toll-Like Receptors / Q000378:metabolism; D016896:Treatment Outcome; D014945:Wound Healing / Q000187:drug effects / Q000276:immunology; D014947:Wounds and Injuries / Q000150:complications / Q000276:immunology / Q000628:therapy
chemical_list: D007155:Immunologic Factors; D008070:Lipopolysaccharides; D051193:Toll-Like Receptors