A bioinspired self assembled dimeric porphyrin pocket that binds electron accepting ligands.
A binding pocket consisting of two zinc porphyrins self assembled by Watson-Crick base pairing is presented. The porphyrin binding pocket is located in the confined environment of a lipid membrane whereas the DNA is located in the water phase. Bidentate electron accepting ligands are shown to coordinate in-between the two porphyrins.
Department of Chemical and Biological Engineering, Chalmers University of Technology, 41296, Göteborg, Sweden.
Karl
K
Börjesson
Jakob G
JG
Woller
Elham
E
Parsa
Jerker
J
Mårtensson
Bo
B
Albinsson
D020029:Base Pairing; D001665:Binding Sites; D040761:Biomimetic Materials / Q000737:chemistry / Q000378:metabolism*; D004247:DNA / Q000737:chemistry / Q000378:metabolism; D019281:Dimerization; D004583:Electrons; D008024:Ligands; D008563:Membrane Lipids / Q000737:chemistry / Q000378:metabolism; D008665:Metalloporphyrins / Q000737:chemistry / Q000378:metabolism*; D008958:Models, Molecular
D008024:Ligands; D008563:Membrane Lipids; D008665:Metalloporphyrins; C017802:zinc hematoporphyrin; D004247:DNA