[A case of long-term survival after curative resection of advanced rectal cancer treated by pre-operative chemoradiotherapy].
We report a long-term survival case of rectal cancer that was initially thought unresectable treated with chemoradiotherapy (CRT). The patient was a 50s female with advanced rectal cancer and liver metastasis. The primary tumor was expanded locally and made abscess around the rectum. We evaluated the primary lesion as unresectable, and we performed CRT after colostomy. After radiation therapy (total 60 Gy) and chemotherapy with S-1 (3 courses), the primary tumor was remarkably reduced. The liver metastasis showed a progressive growth in size but not in number. She underwent complete resection of rectal tumor and partial resection of metastatic liver tumor. Postoperative course was uneventful, and she is alive without a recurrence for 5 years after the surgery.
Dept. of Surgery, Musashino Red Cross Hospital.
Satoshi
S
Okazaki
Shunroh
S
Ohtsukasa
Yutaka
Y
Nakajima
Ayako
A
Kamiya
Hiroto
H
Nagano
Susumu
S
Takamatsu
Yasuyuki
Y
Kawachi
Hiroshi
H
Maruyama
D000964:Antimetabolites, Antineoplastic / Q000627:therapeutic use; D059248:Chemoradiotherapy; D004338:Drug Combinations; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary / Q000628:therapy; D008875:Middle Aged; D010094:Oxonic Acid / Q000627:therapeutic use; D012004:Rectal Neoplasms / Q000473:pathology / Q000628:therapy*; D012074:Remission Induction; D005641:Tegafur / Q000627:therapeutic use; D013997:Time Factors; D014057:Tomography, X-Ray Computed
D000964:Antimetabolites, Antineoplastic; D004338:Drug Combinations; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid