Delayed-onset interface fluid syndrome after laser in situ keratomileusis secondary to combined cataract and vitreoretinal surgery.
A 40-year-old man with a history of laser in situ keratomileusis (LASIK) 13 years earlier had combined cataract extraction and vitreoretinal surgery due to rhegmatogenous retinal detachment and posterior subcapsular cataract. Two weeks postoperatively, he complained of painless visual blurring. Diffuse interface haze was observed, and antiinflammatory treatment including topical steroid and cyclosporine was started. One week later, visual blurring had not improved and intraocular pressure was 27 mm Hg. Interface haze, fluid collection, and flap edema were observed and confirmed by spectral-domain anterior segment optical coherence tomography. After discontinuation of the steroid and addition of IOP-lowering medication, visual acuity and interface fluid collection and haze improved. This case illustrates that interface fluid syndrome can develop more than 10 years after LASIK, triggered by ocular hypertension and inflammation after intraocular surgery.


BACKGROUND
No author has a financial or proprietary interest in any material or method mentioned.
Department of Ophthalmology, Seoul National University College of Medicine, Seoul, and Department of Ophthalmology, Seoul National University Bundang Hospital, Seongnam, Korea.
Sang Beom
SB
Han
Se Joon
SJ
Woo
Joon Young
JY
Hyon
D000328:Adult; D002386:Cataract / Q000150:complications; D015715:Corneal Edema / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D007429:Intraocular Pressure; D020731:Keratomileusis, Laser In Situ / Q000009:adverse effects*; D054018:Lasers, Excimer / Q000009:adverse effects; D019654:Lens Implantation, Intraocular; D008297:Male; D018918:Phacoemulsification; D011183:Postoperative Complications; D012163:Retinal Detachment / Q000150:complications; D013524:Surgical Flaps / Q000473:pathology*; D041623:Tomography, Optical Coherence; D057586:Vitreoretinal Surgery