ERCC1 polymorphisms and risk of adult glioma in a Chinese population: a hospital-based case-control study.
To examine the associations of two polymorphisms in excision repair cross-complementing rodent repair deficiency complementation group 1 (ERCC1) gene, C8092A (rs3212986) and T19007C (rs11615), with the risk of adult glioma, we performed a hospital-based case-control study with 257 new cases of glioma and 278 controls in Wenzhou, China. Results showed that polymorphisms C8092A and T19007C in ERCC1 gene were not associated with the risk of glioma in a Chinese population. Further studies in Chinese populations with larger sample sizes are still warranted.
Department of Neurosurgery, The Second Affiliated Hospital of Wenzhou Medical College, Zhejiang Province, China.
Nu
N
Zhang
Lu-Yang
LY
Lin
Lie-Lie
LL
Zhu
Fan
F
Wu
Hao
H
Wen
Da
D
Pan
Yu-Chuan
YC
Huang
Da-Qing
DQ
Chen
D000328:Adult; D044466:Asian People / Q000235:genetics*; D001932:Brain Neoplasms / Q000209:etiology / Q000235:genetics*; D016022:Case-Control Studies; D004260:DNA Repair; D004268:DNA-Binding Proteins / Q000235:genetics*; D004720:Endonucleases / Q000235:genetics*; D005260:Female; D005838:Genotype; D005910:Glioma / Q000209:etiology / Q000235:genetics*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011110:Polymorphism, Genetic; D012306:Risk
D004268:DNA-Binding Proteins; C071447:ERCC1 protein, human; D004720:Endonucleases