A case report of cecal plasmablastic lymphoma in a HIV-negative patient.
Plasmablastic lymphoma (PBL) is a unique type of diffuse proliferation of large neoplastic lymphoid cells most of which resemble B immunoblasts, but all tumor cells show the immunophenotype of plasma cells. It has a strong predilection for jaw and oral cavity in HIV-positive patients. Incidences of extraoral location of this tumor is increasingly being recognized especially in HIV-negative patients for example, stomach, jejunum, omentum, anorectum, lungs, testes, soft tissues, lymph nodes, bone marrow, skin, and central nervous system. We present a case of PBL found in cecum in an HIV-negative patient. It was accompanied by lung and lymph node involvement and presented as abdominal mass. This is only the second reported case of PBL originating in cecum.
Manchester Royal Infirmary Hospital, Manchester, Lancashire, UK. muhammad_mansur@yahoo.co.uk
Muhammad
M
Mansoor
Fouad Sadik Saied
FS
Alani
Mohammed Babar
MB
Aslam
Santhi N
SN
Kumar
Neil
N
Sahasrabudhe
Durab
D
Khan
D000368:Aged; D002430:Cecal Neoplasms / Q000175:diagnosis*; D017809:Fatal Outcome; D005260:Female; D018023:HIV Seronegativity; D006801:Humans; D016403:Lymphoma, Large B-Cell, Diffuse / Q000175:diagnosis*; D016400:Lymphoma, Large-Cell, Immunoblastic / Q000175:diagnosis*; D010950:Plasma Cells / Q000473:pathology*; D014057:Tomography, X-Ray Computed