Platelet concentrate transport in pneumatic tube systems--does it work?
Blood sample transport via pneumatic tube systems (PTS) reduces the turnaround time of laboratories, but it might influence analysis results. Its effect on platelet concentrates (PCs) is not known. Platelet function was investigated after single and multiple PTS transport in comparison with storage and irradiation. Optical and impedance aggregation, CD-62, and microparticles changed as a result of storage, but not due to transport. Irradiation lowered platelet function independently. Multiple transport impaired thrombin receptor-activating peptide-induced aggregation. This investigation demonstrates the feasibility of PTS transport. As platelet function depends on storage, it may be more important to transfuse fresh PCs.
Maastricht University Medical Centre+, Department of Anaesthesiology and Pain Treatment, University Hospital Maastricht, P. Debyelaan 25, Maastricht, The Netherlands. marcus.lance@mumc.nl
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MD
Lancé
M A E
MA
Marcus
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R
van Oerle
H M S
HM
Theunissen
Y M C
YM
Henskens
D001792:Blood Platelets / Q000737:chemistry*; D001793:Blood Preservation; D005240:Feasibility Studies; D006801:Humans; D015539:Platelet Activation; D010974:Platelet Aggregation; D017713:Platelet Transfusion; D013048:Specimen Handling / Q000379:methods*; D013997:Time Factors