Percutaneous irreversible electroporation of surgically unresectable pancreatic cancer: a case report.
The present report describes a case of percutaneous irreversible electroporation (IRE) in a 78-year-old man with surgically unresectable stage III (tumor/node/metastasis stages, T4N0M0) pancreatic adenocarcinoma. Two ablations were performed for a 4.1-cm mass encasing the celiac and superior mesenteric artery. At 3 months, a solitary liver metastasis developed, which was treated with radiofrequency ablation followed by gemcitabine chemotherapy. At 6-month follow-up, magnetic resonance imaging demonstrated no residual disease and a decreasing cancer antigen 19-9 level. Percutaneous IRE shows promise as a feasible and potentially safe method for local tumor control in patients with surgically unresectable disease.
Cardiovascular and Interventional Radiology Department, Inova Alexandria Hospital, 4320 Seminary Rd, Alexandria, VA 22304, USA. sbagla@alexandriaradiology.com
Sandeep
S
Bagla
Dimitrios
D
Papadouris
D000230:Adenocarcinoma / Q000473:pathology / Q000628:therapy*; D000368:Aged; D017115:Catheter Ablation; D018274:Electroporation / Q000379:methods*; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary / Q000628:therapy; D008279:Magnetic Resonance Imaging; D008297:Male; D009367:Neoplasm Staging; D010190:Pancreatic Neoplasms / Q000473:pathology / Q000628:therapy*