A highly selective fluorescent chemosensor for guanosine-5'-triphosphate via excimer formation in aqueous solution of physiological pH.
A new water-soluble and fluorescent imidazolium-anthracene cyclophane 1 effectively recognizes and differentiates the biologically important GTP and ATP in 100% aqueous solution of physiological pH 7.4. Fluorescence, (1)H-NMR spectra and ab initio calculations demonstrate that excimer formation and fluorescence enhancement occur upon GTP and ATP binding, respectively, through (C-H)(+)···A(-) hydrogen bond interactions.
Center for Superfunctional Materials, Department of Chemistry Pohang University of Science and Technology, Pohang 790-784, Korea.
Nisar
N
Ahmed
Bahareh
B
Shirinfar
Il Seung
IS
Youn
Amita
A
Bist
Vangaru
V
Suresh
Kwang S
KS
Kim
D000255:Adenosine Triphosphate / Q000737:chemistry; D000873:Anthracenes / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000737:chemistry*; D006160:Guanosine Triphosphate / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D007093:Imidazoles / Q000737:chemistry*; D008958:Models, Molecular; D013050:Spectrometry, Fluorescence; D014867:Water / Q000737:chemistry
D000873:Anthracenes; D005456:Fluorescent Dyes; D007093:Imidazoles; D014867:Water; D006160:Guanosine Triphosphate; D000255:Adenosine Triphosphate