Deconstructing hepatitis C virus infection in humanized mice.
Hepatitis C virus is a major medical problem. Novel small-animal models are likely to accelerate the development of more effective therapeutics and a vaccine.
Center for the Study of Hepatitis C, Laboratory for Virology and Infectious Disease, The Rockefeller University, New York, New York, USA.
Marcus
M
Dorner
Alexander
A
Ploss
D000222:Adaptation, Physiological; D000818:Animals; D004195:Disease Models, Animal; D016174:Hepacivirus / Q000472:pathogenicity / Q000502:physiology; D006526:Hepatitis C / Q000209:etiology*; D054884:Host-Pathogen Interactions / Q000235:genetics / Q000502:physiology; D006801:Humans; D051379:Mice; D023822:Tissue Engineering; D014183:Transplantation, Heterologous