[Syringotropic cutaneous T-cell lymphoma mimicking dermatomycosis].
BACKGROUND
Cutaneous syringotropic T-cell lymphoma is a rare form of lymphoma. We report a case involving a misleading cutaneous presentation on the sole of the foot.


METHODS
A 55-year-old woman presented discrete coalescent papules on her left foot, having an anhidrotic appearance, for which a number of antifungal treatments had been given without success. The skin biopsy revealed CD4+ T lymphocytic dermal infiltrate, mainly near the sweat glands, with syringotropism. The diagnosis of syringotropic T-cell lymphoma was reinforced by the presence of dominant cutaneous T-lymphocyte clone in the skin biopsy. Staging tests were negative. Treatment was initiated with an extremely potent (class IV) dermal corticosteroid.


CONCLUSIONS
Syringotropic T-cell lymphoma is an extremely rare form of cutaneous lymphoma similar in presentation to mycosis fungoides, characterised by the mainly perisudoral and syringotropic nature of the lymphocytic infiltrate. The value of this case report lies in the extremely mild nature of the misleading skin lesions, which could only be diagnosed through biopsy. Treatment for this condition is not as yet codified due to the extremely low number of cases reported in the literature.
Service de dermatologie, centre hospitalier du Mans, Le-Mans, France. mfenot@ch-lemans.fr
M
M
Fenot
H
H
Maillard
S
S
Sierra-Fortuny
L-R
LR
De Ybarlucea
P
P
Célérier
D002330:Carmustine / Q000627:therapeutic use; D002990:Clobetasol / Q000627:therapeutic use; D003881:Dermatomycoses / Q000175:diagnosis*; D003951:Diagnostic Errors; D005260:Female; D005534:Foot Diseases / Q000139:chemically induced / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D006801:Humans; D008875:Middle Aged; D009182:Mycosis Fungoides / Q000139:chemically induced / Q000145:classification / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D009824:Ointments / Q000009:adverse effects; D012878:Skin Neoplasms / Q000139:chemically induced / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D013545:Sweat Glands / Q000473:pathology*
D009824:Ointments; D002990:Clobetasol; D002330:Carmustine