Protective antibody responses to influenza A/H1N1/09 vaccination in children with celiac disease.
Patients with celiac disease have an increased risk for severe influenza infection and they show less of a response to certain vaccine types. During the influenza A/H1N1/09 pandemic, we prospectively investigated pandemic vaccine responses in 14 pediatric patients with celiac disease and age-/sex-matched controls. All of the children with celiac disease reached protective antibody titers (≥40) and showed a geometric mean titer comparable with the control group (530 vs 573).
Department of Pediatrics, University Hospitals of Geneva, Geneva, Switzerland. Michela.Tempia-Caliera@hcuge.ch
Michela G
MG
Schäppi
Sara
S
Meier
Michael
M
Bel
Claire-Anne
CA
Siegrist
Klara M
KM
Posfay-Barbe
D000293:Adolescent; D000328:Adult; D000917:Antibody Formation; D016022:Case-Control Studies; D002446:Celiac Disease / Q000150:complications / Q000276:immunology*; D002648:Child; D002675:Child, Preschool; D004198:Disease Susceptibility; D005260:Female; D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype; D007252:Influenza Vaccines / Q000276:immunology*; D007251:Influenza, Human / Q000453:epidemiology / Q000276:immunology / Q000517:prevention & control* / Q000821:virology; D008297:Male; D058873:Pandemics; D011446:Prospective Studies; D012307:Risk Factors; D014611:Vaccination; D055815:Young Adult
D007252:Influenza Vaccines