Human Mycobacterium bovis infection in Buenos Aires: epidemiology, microbiology and clinical presentation.
We performed a retrospective study of clinical, epidemiological and microbiological characteristics of patients with confirmed Mycobacterium bovis infection treated at Francisco Muñiz Hospital, Buenos Aires, Argentina, between 1996 and 2008. A total of 39 patients were  included, accounting for 0.4% of tuberculosis cases in our hospital. Of these, 93% had at least one risk factor for M. bovis; the most frequent was occupational exposure (65%), followed by history of living in a rural area (31%) and consumption of unpasteurised milk (4%). Pulmonary  disease was the most frequent clinical presentation. Rifampicin resistance and multidrug resistance were seen in two patients, both of whom had human immunodeficiency virus infection.
Department of Infectious Diseases, Francisco J. Muñiz Hospital, Buenos Aires, Argentina. dr_ecordova@hotmail.com
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Cordova
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Gonzalo
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Boschi
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Lossa
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Robles
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Poggi
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Ambroggi
D000328:Adult; D000818:Animals; D000995:Antitubercular Agents / Q000494:pharmacology / Q000627:therapeutic use*; D001118:Argentina / Q000453:epidemiology; D005260:Female; D015658:HIV Infections / Q000150:complications; D006801:Humans; D008297:Male; D008875:Middle Aged; D008892:Milk / Q000382:microbiology; D009163:Mycobacterium bovis / Q000302:isolation & purification*; D009784:Occupational Diseases / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology; D012189:Retrospective Studies; D012293:Rifampin / Q000627:therapeutic use; D012307:Risk Factors; D012424:Rural Population; D014376:Tuberculosis / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology; D018088:Tuberculosis, Multidrug-Resistant / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology
D000995:Antitubercular Agents; D012293:Rifampin