[A case whose lung metastasis was detected and resected eleven years after resection of primary colon cancer].
In July 1999, a 79-year-old man underwent sigmoidectomy and D3 lymphadectomy for sigmoid colon cancer (ss, n(-), stage II, cur A). In September 2000, hepatectomy of right lobe and cholecystectomy were performed for his liver metastasis. Every three to six months follow-up had been kept since adjuvant chemotherapy (200 mg/day of 5-FU per os for two years) completed. Eleven years and two months after sigmoidectomy (in September 2010), a chest X-ray examination detected a small nodule in upper area of his right lung, which was diagnosed as either primary lung cancer or metastatic lung tumor followed by chest CT scan and PET-CT examination. In November 2010, laparoscopy-assisted partial resection of his right lung was performed. Histochemical examination of the resected lung tumor resulted cytokeratin 7(-), cytokeratin 20(+) and TTF-1(-), confirming its final diagnosis as lung metastasis from sigmoid colon cancer. He has been alive for six months without any recurrence since resection of his lung metastasis. It was a very rare case to have more than ten-year interval between colon cancer resection and detection of its lung metastasis. However, when we diagnosed the patient with lung tumor, who had undergone a colorectal resection, we should consider if he had a lung metastasis from colorectal cancer.
Dept. of Surgery, Kansai Rosai Hospital.
Shu
S
Okamura
Ken
K
Nakata
Rei
R
Suzuki
Michiko
M
Hamanaka
Hisako
H
Ono
Chieko
C
Uchiyama
Takashi
T
Kanemura
Masayoshi
M
Kobayashi
Yasumasa
Y
Yoshioka
Ayako
A
Yanai
Atsushi
A
Takeno
Shin
S
Nakahira
Hirofumi
H
Miki
Yutaka
Y
Takeda
Shigeyuki
S
Tamura
D000368:Aged; D003110:Colonic Neoplasms / Q000473:pathology* / Q000601:surgery; D005500:Follow-Up Studies; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis* / Q000556:secondary / Q000601:surgery; D008297:Male; D064847:Multimodal Imaging; D049268:Positron-Emission Tomography; D013997:Time Factors; D014057:Tomography, X-Ray Computed