Dopamine: effect of concentration and pH on the electron emission. Reaction mechanisms.
Dopamine (DA) in airfree, aqueous solution (pH 7.4; 37°C) is able to emit e(-)(aq) when electronically excited in its singlet state by monochromatic UV light (λ=254 nm; 4.85 eV/hν). The quantum yield Q(e(-)(aq)), was studied in dependence of DA concentration and pH of the media. The DA transients resulting from the electron emission form products, which also have the ability to emit e(-)(aq), but with much lower yield. Since DA in the ground state can consume e(-)(aq), it is classified as an electron mediator. Some biological consequences based on the e(-)(aq) emission are mentioned.
University of Vienna, Section of Radiation Biology, Faculty of Life Sciences, UZA II, A-1090 Vienna, Austria. nikola.getoff@univie.ac.at
Nikola
N
Getoff
Eric
E
Brenn
Shaobin
S
Ying
D000465:Algorithms; D004298:Dopamine / Q000737:chemistry*; D004583:Electrons; D006863:Hydrogen-Ion Concentration; D008956:Models, Chemical; D015394:Molecular Structure; D010084:Oxidation-Reduction / Q000528:radiation effects; D010782:Photolysis / Q000528:radiation effects; D011789:Quantum Theory; D012996:Solutions / Q000737:chemistry; D014466:Ultraviolet Rays; D014867:Water / Q000737:chemistry
D012996:Solutions; D014867:Water; D004298:Dopamine