Health-related quality of life of pediatric intensive care survivors.
OBJECTIVE
To assess the health-related quality of life (HRQoL) of children surviving to pediatric intensive care discharge.


METHODS
A prospective evaluation of HRQoL at admission and 6 months later was carried out with children aged 6 years or more, admitted to three tertiary pediatric intensive care units (PICUs) from May 2002 to June 2004. HRQoL was measured with the Health Utilities Index Mark 3 (HUI3) questionnaire, administered to a child's proxy.


RESULTS
From the 517 eligible admissions, 44 children died in the PICU (8.5%) and 320 cases were evaluated at admission; among those, follow-up data were available in 252 cases. There were no statistically significant differences between preadmission and follow-up HUI3 global scores (medians [interquartile range] of 0.86 [0.42-1.00] and 0.83 [0.45-1.00]; p = 0.674, respectively). At the individual level, 21% of children had their HRQoL unchanged, improvement was seen in 40% and deterioration in 38% of the cases. Severe disability before admission (HUI3 global score < 0.70) was present in 36% of the cases, with improvement at the 6-month follow-up in 60% of them. Among those with deterioration of HRQoL at follow-up, 45% were trauma victims.


CONCLUSIONS
Although the HRQoL was globally similar in both evaluations, several differences were found at the individual level. Children with low preadmission HRQoL (severe disability) may benefit from pediatric intensive care, since many of these children improved their HRQoL compared to preadmission status.
Unidade de Cuidados Intensivos Pediátricos, Unidade Autónoma de Gestão da Mulher e da Criança (UAG-MC), Hospital São João, Porto, Portugal. francisco.a.cunha@sapo.pt
Francisco
F
Cunha
Luís
L
Almeida-Santos
Armando
A
Teixeira-Pinto
Farela
F
Neves
Deolinda
D
Barata
Altamiro
A
Costa-Pereira
D000293:Adolescent; D002648:Child; D004812:Epidemiologic Methods; D005260:Female; D006304:Health Status; D006760:Hospitalization / Q000706:statistics & numerical data*; D006801:Humans; D015278:Intensive Care Units, Pediatric; D008297:Male; D010351:Patient Discharge / Q000706:statistics & numerical data; D011788:Quality of Life; D017741:Survivors / Q000706:statistics & numerical data*; D013997:Time Factors; D016896:Treatment Outcome