Polyelectrolyte complex materials consisting of antibacterial and cell-supporting layers.
The characterization of a polyelectrolyte complex material comprised of two biopolymers, a chitosan upper layer and a gellan gum under layer, is reported. It is shown that the upper layer of chitosan with incorporated levofloxacin displays an antibacterial activity, while the under layer of a gellan gum/TiO(2)  composite supports the growth of fibroblastic cells.
Soft Materials Group, School of Chemistry, University of Wollongong, Wollongong, NSW 2522, Australia.
Khairul Anuar
KA
Mat Amin
Kerry J
KJ
Gilmore
Jake
J
Matic
Stephen
S
Poon
Mark J
MJ
Walker
Mark R
MR
Wilson
Marc
M
in het Panhuis
D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology; D001672:Biocompatible Materials / Q000138:chemical synthesis* / Q000494:pharmacology; D049109:Cell Proliferation / Q000187:drug effects; D002470:Cell Survival / Q000187:drug effects; D048271:Chitosan / Q000737:chemistry*; D004339:Drug Compounding; D004926:Escherichia coli / Q000187:drug effects; D005347:Fibroblasts / Q000166:cytology / Q000187:drug effects; D064704:Levofloxacin; D050296:Microbial Viability / Q000187:drug effects; D015242:Ofloxacin / Q000737:chemistry / Q000494:pharmacology*; D011135:Polysaccharides, Bacterial / Q000737:chemistry*; D014025:Titanium / Q000737:chemistry
D000900:Anti-Bacterial Agents; D001672:Biocompatible Materials; D011135:Polysaccharides, Bacterial; C009495:titanium dioxide; D064704:Levofloxacin; C048288:gellan gum; D048271:Chitosan; D015242:Ofloxacin; D014025:Titanium