Chemical compositions of the essential oils of the aerial parts of Chamaemelum mixtum (L.) Alloni.
The chemical compositions of the aerial parts essential oils of  Chamaemelum mixtum  (L.) Alloni from Corsica and Sardinia were investigated employing gas chromatography and gas chromatography-mass spectrometry (GC-MS). The structure of (Z)-heptadeca-9,16-dien-7-one, a natural compound not previously described, was elucidated by GC-MS (electron impact and chemical ionization) and one-dimensional and two-dimensional nuclear magnetic resonance spectroscopy. The variation in C. mixtum essential oil was studied, and statistical analysis showed the clustering of oil samples into three groups according to the amount of oxygenated compounds; these groups correlated to the harvest area. The strong biological activity of the oxygenated fraction (minimum inhibitory concentration of <0.1 mg/mL) of the Corsican oil against  Candida albicans ,  Citrobacter frendii ,  Enterococcus faecalis ,  Escherichia coli ,  Klebsiella pneumoniae ,  Listeria monocytogenes , and  Staphyllococcus aureus  can be attributed to the presence of irregular monoterpene alcohols and (Z)-heptadeca-9,16-dien-7-one.
Laboratoire Chimie des Produits Naturels, UMR CNRS 6134, Université de Corse, B.P. 52, 20250 Corti, France.
Florent
F
Darriet
Mourad
M
Bendahou
Jean
J
Costa
Alain
A
Muselli
D000900:Anti-Bacterial Agents; D002176:Candida albicans / Q000187:drug effects; D031167:Chamaemelum / Q000737:chemistry*; D002849:Chromatography, Gas; D005602:France; D008401:Gas Chromatography-Mass Spectrometry; D007558:Italy; D039821:Monoterpenes / Q000032:analysis / Q000494:pharmacology; D009822:Oils, Volatile / Q000737:chemistry* / Q000494:pharmacology; D035261:Plant Components, Aerial / Q000737:chemistry*
D000900:Anti-Bacterial Agents; D039821:Monoterpenes; D009822:Oils, Volatile