HIV-negative disseminated Kaposi's sarcoma in a Taiwanese patient.
Kaposi's sarcoma is a common malignancy associated with HIV/AIDS. Herein, we describe the case of a 26-year-old man who presented with bilateral neck and inguinal lymphadenopathy, a massive tumor on the gum, and a nodule over the left eye. A series of tests, including tumor biopsies, were performed, and disseminated Kaposi's sarcoma with human herpesvirus 8 infection was diagnosed. To test for HIV, we used enzyme-linked immunosorbent assay and real-time polymerase chain reaction, but the results were negative. The patient was treated by biweekly intravenous infusion of pegylated liposomal doxorubicin (25 mg/m(2)), and this treatment resulted in a partial response.
Division of Hematology-Oncology, Department of Internal Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
Chiung-Tang
CT
Huang
Chao-Sung
CS
Chang
Hung-Chune
HC
Maa
Shih-Feng
SF
Cho
Ta-Chih
TC
Liu
D000328:Adult; D000903:Antibiotics, Antineoplastic / Q000627:therapeutic use; D004317:Doxorubicin / Q000627:therapeutic use; D005134:Eye Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000821:virology; D005887:Gingival Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000821:virology; D019288:Herpesvirus 8, Human; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000821:virology; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis* / Q000188:drug therapy / Q000821:virology; D011859:Radiography; D012514:Sarcoma, Kaposi / Q000175:diagnosis* / Q000188:drug therapy / Q000821:virology; D013624:Taiwan; D016896:Treatment Outcome
D000903:Antibiotics, Antineoplastic; D004317:Doxorubicin