Primary follicular lymphoma of the testis in children and adolescents.
This study reports 6 cases of primary follicular lymphoma of the testis (PFLT) in children and adolescents correlated with clinical presentation, pathologic features, treatment, and outcome. All 6 patients (age, 3 to 16 y; median, 4 y) had PFLT grade 3 with disease limited to the testis, completely resected and treated with 2 courses of chemotherapy (cyclophosphamide, vincristine, prednisone, doxorubicin). Event-free survival was 100% (follow-up: median, 73 mo; mean, 53 mo; range, 6 to 96 mo). In conclusion, clinical outcome in children and adolescents with PFLT is excellent with treatment including complete surgical resection and 2 courses of cyclophosphamide, vincristine, prednisone, doxorubicin.
Children's Cancer Group (CCG) (now part of Children's Oncology Group), Operations Center, Arcadia, Arcadia, CA 91006, USA.
Mark A
MA
Lones
Martine
M
Raphael
Keith
K
McCarthy
Andrew
A
Wotherspoon
Marie-Josee
MJ
Terrier-Lacombe
Alan D
AD
Ramsay
Ken
K
Maclennan
Mitchell S
MS
Cairo
Mary
M
Gerrard
Jean
J
Michon
Catherine
C
Patte
Ross
R
Pinkerton
Leonard
L
Sender
Anne
A
Auperin
Richard
R
Sposto
Claire
C
Weston
Nyla A
NA
Heerema
Warren G
WG
Sanger
Daniel
D
von Allmen
Sherrie L
SL
Perkins
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D006801:Humans; D008224:Lymphoma, Follicular / Q000401:mortality / Q000473:pathology / Q000628:therapy*; D008297:Male; D013736:Testicular Neoplasms / Q000401:mortality / Q000473:pathology / Q000628:therapy*