Catalytic diastereoselective reduction of α,β-epoxy and α,β-aziridinyl ynones.
The Noyori transfer hydrogenation of α,β-epoxy and α,β-aziridinyl ynones leads to the corresponding α,β-epoxy or α,β-aziridinyl propargylic alcohols with high reagent-controlled diastereoselectivity.
Laboratoire de Chimie Organique, ESPCI ParisTech, CNRS, 10 rue Vauquelin, 75231 Paris Cedex 05, France.
Valérie
V
Druais
Christophe
C
Meyer
Janine
J
Cossy
D000438:Alcohols / Q000737:chemistry; D001388:Aziridines / Q000737:chemistry*; D002384:Catalysis; D004852:Epoxy Compounds / Q000737:chemistry*; D006865:Hydrogenation; D015394:Molecular Structure; D010084:Oxidation-Reduction; D013237:Stereoisomerism
D000438:Alcohols; D001388:Aziridines; D004852:Epoxy Compounds; C033132:aziridine