Bleomycin in malignant pleural effusion. Choose talc pleurodesis.
Not more effective than talc in preventing recurrent pleural effusions, based on a review with meta-analysis of 7 trials in 256 patients. Bleomycin carries a risk of systemic adverse effects and treatment errors.
D000903:Antibiotics, Antineoplastic / Q000009:adverse effects*; D001761:Bleomycin / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D016066:Pleural Effusion, Malignant / Q000188:drug therapy*; D018700:Pleurodesis / Q000379:methods*; D013627:Talc / Q000008:administration & dosage*
D000903:Antibiotics, Antineoplastic; D001761:Bleomycin; D013627:Talc