Transcriptional priming of cytoplasmic post-transcriptional regulation.
Recent evidence suggests that post-transcriptional events that are executed in the cytoplasm can be predetermined during transcription. Here, I speculate that this is a widespread mode of regulation and discuss the potential mechanisms, advantages and implications of such a regulatory strategy.
Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel. itay.tirosh@weizmann.ac.il
Itay
I
Tirosh
D021581:Active Transport, Cell Nucleus; D000818:Animals; D003593:Cytoplasm / Q000378:metabolism*; D006801:Humans; D008957:Models, Genetic; D011485:Protein Binding; D014176:Protein Biosynthesis; D012323:RNA Processing, Post-Transcriptional; D012333:RNA, Messenger / Q000235:genetics* / Q000378:metabolism; D016601:RNA-Binding Proteins / Q000378:metabolism; D014158:Transcription, Genetic
D012333:RNA, Messenger; D016601:RNA-Binding Proteins