Congenital and acquired neutropenias consensus guidelines on therapy and follow-up in childhood from the Neutropenia Committee of the Marrow Failure Syndrome Group of the AIEOP (Associazione Italiana Emato-Oncologia Pediatrica).
The management of congenital and acquired neutropenias presents some differences according to the type of the disease. Treatment with recombinant human granulocyte-colony stimulating factor (G-CSF) is not standardized and scanty data are available on the best schedule to apply. The frequency and the type of longitudinal controls in patients affected with neutropenias are not usually discussed in the literature. The Neutropenia Committee of the Marrow Failure Syndrome Group (MFSG) of the Associazione Italiana di Emato-Oncologia Pediatrica (AIEOP) elaborated this document following design and methodology formerly approved by the AIEOP board. The panel of experts reviewed the literature on the topic and participated in a conference producing a document that includes recommendations on neutropenia treatment and timing of follow-up.
Haematology Unit, G. Gaslini Children's Hospital, Genova, Italy. francescafioredda@ospedale-gaslini.ge.it
Francesca
F
Fioredda
Michaela
M
Calvillo
Sonia
S
Bonanomi
Tiziana
T
Coliva
Fabio
F
Tucci
Piero
P
Farruggia
Marta
M
Pillon
Baldassarre
B
Martire
Roberta
R
Ghilardi
Ugo
U
Ramenghi
Daniela
D
Renga
Giuseppe
G
Menna
Anna
A
Pusiol
Angelica
A
Barone
Eleonora
E
Gambineri
Giovanni
G
Palazzi
Gabriella
G
Casazza
Marina
M
Lanciotti
Carlo
C
Dufour
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000494:pharmacology / Q000627:therapeutic use*; D001853:Bone Marrow / Q000187:drug effects / Q000473:pathology; D016026:Bone Marrow Transplantation; D002648:Child; D032921:Consensus; D019468:Disease Management; D004334:Drug Administration Schedule; D016179:Granulocyte Colony-Stimulating Factor / Q000494:pharmacology / Q000627:therapeutic use*; D006801:Humans; D009503:Neutropenia / Q000145:classification / Q000473:pathology / Q000628:therapy*; D014182:Transplantation, Autologous; D014184:Transplantation, Homologous
D016179:Granulocyte Colony-Stimulating Factor