Feasibility of conservative medical treatment for pyoderma gangrenosum.
Pyoderma gangrenosum (PG) is a chronic skin disease with an incidence of 3-10 per million, and it is often associated with underlying systemic disease. A case of PG of the left leg successfully treated with local debridement and advanced and compression dressings, without systemic treatment is reported. Progression and healing of the ulcer was incredibly rapid. The treatment of PG usually consists of systemic administration of corticosteroids. But wherever the administration of systemic immunosuppressive therapy is impractical, a topical treatment can be used. This type of treatment does not represent a mere palliative, but could be significant for healing, as in the case of our patient.
Department of Dermatology and Plastic, Reconstructive and Aesthetic Surgery, University of Rome La Sapienza, Policlinico Umberto I, Viale Pantelleria, 35, Scala B, Interno 1/A, 00141, Rome, Italy.
Paolo
P
Fioramonti
Maria Giuseppina
MG
Onesti
Pasquale
P
Fino
Silvia
S
Di Ronza
Valentina
V
Sorvillo
Paolo
P
Persichetti
D000890:Anti-Infective Agents / Q000627:therapeutic use; D002939:Ciprofloxacin / Q000627:therapeutic use; D058128:Compression Bandages; D003646:Debridement; D005240:Feasibility Studies; D006801:Humans; D007871:Leg Ulcer / Q000382:microbiology / Q000473:pathology / Q000628:therapy*; D009779:Occlusive Dressings; D017511:Pyoderma Gangrenosum / Q000382:microbiology / Q000473:pathology / Q000628:therapy*; D013203:Staphylococcal Infections / Q000188:drug therapy / Q000382:microbiology; D013211:Staphylococcus aureus / Q000187:drug effects; D014945:Wound Healing / Q000187:drug effects
D000890:Anti-Infective Agents; D002939:Ciprofloxacin