Human stem cell-derived cardiomyocytes for pharmacological and toxicological modeling.
Cardiomyocytes derived from human pluripotent stem cells have advantages for modeling in terms of phenotype, longevity in culture, ease of transfection, and high-throughput capability.
The National Heart and Lung Institute, Imperial College, London, United Kingdom. sian.harding@imperial.ac.uk
Sian E
SE
Harding
D004353:Drug Evaluation, Preclinical; D057166:High-Throughput Screening Assays; D006801:Humans; D008955:Models, Cardiovascular; D032383:Myocytes, Cardiac / Q000166:cytology* / Q000187:drug effects*; D039904:Pluripotent Stem Cells / Q000166:cytology* / Q000187:drug effects*