Childhood osteosarcoma of greater wing of sphenoid:  case report and review of literature.
Primary osteosarcoma of skull base is extremely rare. We present a case of primary osteosarcoma arising in greater wing of sphenoid in a child. Our patient had an incomplete excision after which he received adjuvant chemotherapy and radiotherapy. There was good response to adjuvant chemoradiotherapy and the patient is disease free at a follow-up of 18 months. Treatment of skull base osteosarcomas is difficult, as complete excision is often not possible. To the best of our knowledge, this is the first case of sphenoid wing osteosarcoma in childhood to be reported in literature.
Oculoplastics and Ocular Oncology Service, Department of Medical Oncology, Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.
Rachna
R
Meel
Sanjay
S
Thulkar
Mehar Chand
MC
Sharma
Pandjatcharan
P
Jagadesan
Bidhu Kalyan
BK
Mohanti
Suresh Chandra
SC
Sharma
Sameer
S
Bakhshi
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002648:Child; D003131:Combined Modality Therapy; D006801:Humans; D008297:Male; D019635:Neurosurgical Procedures; D012516:Osteosarcoma / Q000473:pathology* / Q000628:therapy; D020266:Radiotherapy, Conformal; D019292:Skull Base Neoplasms / Q000473:pathology* / Q000628:therapy; D013100:Sphenoid Bone / Q000473:pathology*