The blessings and curses of C57BL/6 substrains in mouse genetic studies.
Phenotypic and genetic differences among C57BL/6 substrains are accumulating. Investigators must address these differences to improve the quality of their studies.
Department of Human Genetics, The University of Chicago, Chicago, Illinois, USA. camron@uchicago.edu
Camron D
CD
Bryant
D000818:Animals; D051379:Mice; D008810:Mice, Inbred C57BL / Q000145:classification* / Q000235:genetics*; D018345:Mice, Knockout / Q000145:classification / Q000235:genetics; D010641:Phenotype; D020641:Polymorphism, Single Nucleotide; D013045:Species Specificity