Divergent ancestral lineages of newfound hantaviruses harbored by phylogenetically related crocidurine shrew species in Korea.
Spurred by the recent isolation of a novel hantavirus, named Imjin virus (MJNV), from the Ussuri white-toothed shrew (Crocidura lasiura), targeted trapping was conducted for the phylogenetically related Asian lesser white-toothed shrew (Crocidura shantungensis). Pair-wise alignment and comparison of the S, M and L segments of a newfound hantavirus, designated Jeju virus (JJUV), indicated remarkably low nucleotide and amino acid sequence similarity with MJNV. Phylogenetic analyses, using maximum likelihood and Bayesian methods, showed divergent ancestral lineages for JJUV and MJNV, despite the close phylogenetic relationship of their reservoir soricid hosts. Also, no evidence of host switching was apparent in tanglegrams, generated by TreeMap 2.0β.
Infectious Disease Surveillance Center, National Institute of Infectious Diseases, Toyama 1-23-1, Shinjuku, Tokyo 162-8640, Japan.
Satoru
S
Arai
Se Hun
SH
Gu
Luck Ju
LJ
Baek
Kenji
K
Tabara
Shannon N
SN
Bennett
Hong-Shik
HS
Oh
Nobuhiro
N
Takada
Hae Ji
HJ
Kang
Keiko
K
Tanaka-Taya
Shigeru
S
Morikawa
Nobuhiko
N
Okabe
Richard
R
Yanagihara
Jin-Won
JW
Song
D000595:Amino Acid Sequence; D000818:Animals; D019143:Evolution, Molecular; D006476:Orthohantavirus / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification*; D008969:Molecular Sequence Data; D010802:Phylogeny; D056910:Republic of Korea; D012788:Shrews / Q000821:virology*