Candida dubliniensis endophthalmitis: first case in North America.
To report an unusual case of endogenous fungal endophthalmitis due to Candida dubliniensis. Interventional case report of a 27-year-old immunocompetent male with loss of vision, dense vitritis, and chorioretinal infiltrates, who underwent a diagnostic pars plana vitrectomy. Microbiology cultures obtained by a diagnostic vitrectomy were positive for the growth of C. dubliniensis. This infectious process was then appropriately treated with intravitreal amphotericin B and systemic fluconazole with resolution of the endophthalmitis. Endogenous fungal endophthalmitis is a condition that can masquerade other more common causes of endophthalmitis. Atypical cases of endophthalmitis may benefit from diagnostic pars plana vitrectomy for prompt diagnosis and treatment.
Department of Ophthalmology, School of Medicine, West Virginia University Eye Institute, 1 Stadium Drive, Morgantown, WV 26505, USA. locombia66@yahoo.com
Diego G
DG
Espinosa-Heidmann
Brian D
BD
McMillan
P Rocco
PR
Lasala
Jonathan
J
Stanley
Cristoforo R
CR
Larzo
D000328:Adult; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use; D002175:Candida / Q000302:isolation & purification*; D003937:Diagnosis, Differential; D009877:Endophthalmitis / Q000382:microbiology* / Q000473:pathology / Q000628:therapy; D015821:Eye Infections, Fungal / Q000382:microbiology* / Q000473:pathology / Q000628:therapy; D006801:Humans; D058449:Intravitreal Injections; D008297:Male; D014821:Vitrectomy; D014822:Vitreous Body / Q000382:microbiology* / Q000473:pathology / Q000601:surgery; D014903:West Virginia
D000900:Anti-Bacterial Agents