ZnO-based amperometric enzyme biosensors.
Nanostructured ZnO with its unique properties could provide a suitable microenvironment for immobilization of enzymes while retaining their biological activity, and thus lead to an expanded use of this nanomaterial for the construction of electrochemical biosensors with enhanced analytical performance. ZnO-based enzyme electrochemical biosensors are summarized in several tables for an easy overview according to the target biosensing analyte (glucose, hydrogen peroxide, phenol and cholesterol), respectively. Moreover, recent developments in enzyme electrochemical biosensors based on ZnO nanomaterials are reviewed with an emphasis on the fabrications and features of ZnO, approaches for biosensor construction (e.g., modified electrodes and enzyme immobilization) and biosensor performances.
School of Electronic Science and Engineering, Southeast University, Nanjing 210096, China. Zhao_zw@seu.edu.cn
Zhiwei
Z
Zhao
Wei
W
Lei
Xiaobing
X
Zhang
Baoping
B
Wang
Helong
H
Jiang
D015374:Biosensing Techniques; D002784:Cholesterol / Q000032:analysis; D055664:Electrochemical Techniques; D004798:Enzymes / Q000378:metabolism*; D005947:Glucose / Q000032:analysis; D006801:Humans; D006861:Hydrogen Peroxide / Q000032:analysis; D049329:Nanostructures / Q000737:chemistry / Q000648:ultrastructure; D010636:Phenols / Q000032:analysis; D015034:Zinc Oxide / Q000737:chemistry*
D004798:Enzymes; D010636:Phenols; D002784:Cholesterol; D006861:Hydrogen Peroxide; D005947:Glucose; D015034:Zinc Oxide