Towards a post-traumatic subtype of obsessive-compulsive disorder.
We evaluated whether traumatic events are associated with a distinctive pattern of socio-demographic and clinical features of obsessive-compulsive disorder (OCD). We compared socio-demographic and clinical features of 106 patients developing OCD after post-traumatic stress disorder (PTSD; termed post-traumatic OCD), 41 patients developing OCD before PTSD (pre-traumatic OCD), and 810 OCD patients without any history of PTSD (non-traumatic OCD) using multinomial logistic regression analysis. A later age at onset of OCD, self-mutilation disorder, history of suicide plans, panic disorder with agoraphobia, and compulsive buying disorder were independently related to post-traumatic OCD. In contrast, earlier age at OCD onset, alcohol-related disorders, contamination-washing symptoms, and self-mutilation disorder were all independently associated with pre-traumatic OCD. In addition, patients with post-traumatic OCD without a previous history of obsessive-compulsive symptoms (OCS) showed lower educational levels, greater rates of contamination-washing symptoms, and more severe miscellaneous symptoms as compared to post-traumatic OCD patients with a history of OCS.
Anxiety and Depression Research Program, Institute of Psychiatry, Federal University of Rio de Janeiro, Brazil. lfontenelle@gmail.com
Leonardo F
LF
Fontenelle
Luca
L
Cocchi
Ben J
BJ
Harrison
Roseli G
RG
Shavitt
Maria Conceição
MC
do Rosário
Ygor A
YA
Ferrão
Maria Alice
MA
de Mathis
Aristides V
AV
Cordioli
Murat
M
Yücel
Christos
C
Pantelis
Jair de Jesus
Jde J
Mari
Euripedes C
EC
Miguel
Albina R
AR
Torres
D000328:Adult; D003192:Compulsive Behavior / Q000145:classification* / Q000175:diagnosis; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009770:Obsessive Behavior / Q000145:classification* / Q000175:diagnosis; D009771:Obsessive-Compulsive Disorder / Q000145:classification* / Q000175:diagnosis; D011569:Psychiatric Status Rating Scales; D012720:Severity of Illness Index; D013313:Stress Disorders, Post-Traumatic / Q000145:classification* / Q000175:diagnosis