Ligation of the ovarian pedicles in dogs with a resorbable self-locking device--a long-term follow-up study.
A prospective clinical trial was performed to evaluate applicability, hemostatic efficiency, and long-term tissue reactions of a novel medical device. The device was made of polydioxanone and designed in principle as a cable-tie with a flexible band running through a locking case. It was tested for ligation of the ovarian pedicles during ovariohysterectomy in nine intact female dogs. The dogs were followed-up monthly by physical examination and ultrasonography of the abdomen for 5-12 months after surgery. Macroscopic and histological post mortem examinations were performed in two dogs 7 and 18 months after surgery. Hemostasis was achieved with the devices although 1 of the 18 devices needed further tightening during a reoperation. Ultrasonography revealed a hyperechoic device that caused acoustic shadowing, which decreased over time indicating gradual resorption. Post mortem examinations demonstrated adhesions and a local transient tissue reaction at site of the device. The results show that the device may be a future alternative for ligation of ovarian pedicles in dogs.
Department of Clinical Sciences, Swedish University of Agricultural Sciences, Uppsala, Sweden. Odd.Hoglund@slu.se
Odd V
OV
Höglund
Ragnvi
R
Hagman
Kerstin
K
Olsson
Carolina
C
Carlsson
Fredrik
F
Södersten
Anne-Sofie
AS
Lagerstedt
D000818:Animals; D004285:Dogs / Q000601:surgery*; D004867:Equipment Design / Q000662:veterinary; D005260:Female; D006488:Hemostasis, Surgical / Q000295:instrumentation / Q000662:veterinary; D007044:Hysterectomy / Q000009:adverse effects / Q000295:instrumentation / Q000662:veterinary*; D008026:Ligation / Q000295:instrumentation / Q000662:veterinary; D008422:Materials Testing; D010052:Ovariectomy / Q000009:adverse effects / Q000295:instrumentation / Q000662:veterinary*; D010053:Ovary / Q000601:surgery; D016687:Polydioxanone; D011183:Postoperative Complications / Q000517:prevention & control / Q000662:veterinary; D011446:Prospective Studies
D016687:Polydioxanone