Genetic diversity and drug susceptibility of Mycobacterium tuberculosis isolates from Zunyi, one of the highest-incidence-rate areas in China.
Mycobacterium tuberculosis isolates from Zunyi were found more diversified but clustered less frequently to the Beijing family compared to isolates from other areas of China. These observations, on top of the fact that the Zunyi area has a high prevalence of multidrug-resistant tuberculosis (MDR-TB), support the notion that Beijing family isolates may not be linked to MDR-TB.
Department of Respiratory Medicine, Affiliated Hospital of Zunyi Medical College, Zunyi, Guizhou, China. lingjuncd@yahoo.com
Ling
L
Chen
Nana
N
Li
Zhiguang
Z
Liu
Mei
M
Liu
Bing
B
Lv
Jianhua
J
Wang
Jianyong
J
Zhang
Kanglin
K
Wan
Hong
H
Zhang
D000995:Antitubercular Agents / Q000494:pharmacology*; D002681:China / Q000453:epidemiology; D016000:Cluster Analysis; D024901:Drug Resistance, Multiple, Bacterial; D014644:Genetic Variation; D006801:Humans; D015994:Incidence; D008826:Microbial Sensitivity Tests; D058889:Molecular Typing; D009169:Mycobacterium tuberculosis / Q000145:classification* / Q000187:drug effects* / Q000235:genetics / Q000302:isolation & purification; D014376:Tuberculosis / Q000453:epidemiology* / Q000382:microbiology*
D000995:Antitubercular Agents