A pilot study of the nutritional status of opiate-using pregnant women on methadone maintenance therapy.
Pregnant women in methadone maintenance therapy may have poor nutrition during pregnancy. In 2006-2008, methadone-treated pregnant women (n = 22) were recruited at an urban academic medical center and compared with nondrug-using pregnant women (n = 119) at 20-35 weeks' gestation. We measured adiposity using prepregnancy body mass index (BMI), dietary intake using a food frequency questionnaire, and micronutrient and essential fatty acid status using biomarkers. Methadone-treated women had lower BMI, consumed more calories, had lower serum carotenoid concentrations, and higher plasma homocysteine concentrations than controls. The study's limitations and implications for future research are discussed.
Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA. let20@pitt.edu
Laura Elizabeth
LE
Tomedi
Debra L
DL
Bogen
Barbara H
BH
Hanusa
Katherine L
KL
Wisner
Lisa M
LM
Bodnar
D000328:Adult; D001823:Body Composition; D015992:Body Mass Index; D002149:Energy Intake; D005228:Fatty Acids, Essential / Q000097:blood; D005260:Female; D006801:Humans; D044342:Malnutrition / Q000150:complications*; D008691:Methadone / Q000627:therapeutic use*; D018977:Micronutrients / Q000097:blood; D009752:Nutritional Status; D058850:Opiate Substitution Treatment; D009293:Opioid-Related Disorders / Q000150:complications / Q000534:rehabilitation; D010865:Pilot Projects; D011247:Pregnancy; D011248:Pregnancy Complications; D037841:Pregnant People
D005228:Fatty Acids, Essential; D018977:Micronutrients; D008691:Methadone