Successful treatment of severe disruptive disorder featuring symptoms of the Klüver-Bucy Syndrome following a massive right temporal-parietal hemorrhage.
We know little about effective treatment for patients suffering from partial or complete Klüver-Bucy Syndrome (KBS) and other disruptive behaviors following a stroke. Reported cases have shown that certain medication, given alone or combined, can be partially effective. In this specific case study, we will try to demonstrate the effectiveness of a combination of carbamazepine, clonidine, quetiapine and methylphenidate in the alleviating of these symptoms. The wide range of symptoms found in KBS led us to use several kinds of psychotropic medication in spite of the inherent risks associated to polypharmacy.
Luigi
L
De Benedictis
Alexandre
A
Dumais
Pierre
P
Landry
D000316:Adrenergic alpha-Agonists / Q000627:therapeutic use; D001289:Attention Deficit Disorder with Hyperactivity / Q000188:drug therapy / Q000209:etiology / Q000523:psychology; D019958:Attention Deficit and Disruptive Behavior Disorders / Q000209:etiology* / Q000523:psychology / Q000628:therapy*; D000697:Central Nervous System Stimulants / Q000627:therapeutic use; D002533:Cerebral Angiography; D003000:Clonidine / Q000627:therapeutic use; D003128:Coma / Q000209:etiology; D004569:Electroencephalography; D005260:Female; D006801:Humans; D020300:Intracranial Hemorrhages / Q000150:complications / Q000523:psychology / Q000628:therapy*; D020232:Kluver-Bucy Syndrome / Q000150:complications / Q000523:psychology / Q000628:therapy*; D008774:Methylphenidate / Q000627:therapeutic use; D009483:Neuropsychological Tests; D010296:Parietal Lobe / Q000473:pathology; D012725:Sexual Behavior; D020521:Stroke / Q000150:complications / Q000523:psychology / Q000628:therapy; D013702:Temporal Lobe / Q000473:pathology; D015899:Tomography, Emission-Computed, Single-Photon; D014057:Tomography, X-Ray Computed; D055815:Young Adult
D000316:Adrenergic alpha-Agonists; D000697:Central Nervous System Stimulants; D008774:Methylphenidate; D003000:Clonidine