Understanding the mechanism of heat stress tolerance caused by high trehalose accumulation in Saccharomyces cerevisiae using DNA microarray.
DNA microarray analysis was performed to examine the stress tolerance mechanism of a Saccharomyces cerevisiae recombinant strain exhibiting high trehalose accumulation and heat stress tolerance. Results suggest that the upregulation of sugar transporter genes is one of the key events for heat stress tolerance of the recombinant strain.
Department of Bioinformatic Engineering, Graduate School of Information Science and Technology, Osaka University, 1-5 Yamadaoka, Suita,Osaka 565-0871, Japan.
Siraje Arif
SA
Mahmud
Takashi
T
Hirasawa
Chikara
C
Furusawa
Katsunori
K
Yoshikawa
Hiroshi
H
Shimizu
D015966:Gene Expression Regulation, Fungal; D006358:Hot Temperature; D020411:Oligonucleotide Array Sequence Analysis; D012441:Saccharomyces cerevisiae / Q000235:genetics / Q000378:metabolism / Q000502:physiology*; D029701:Saccharomyces cerevisiae Proteins / Q000235:genetics / Q000378:metabolism; D013312:Stress, Physiological / Q000235:genetics; D014199:Trehalose / Q000378:metabolism*
D029701:Saccharomyces cerevisiae Proteins; D014199:Trehalose