[Primary choriocarcinoma of the maxillary gingival].
BACKGROUND
Primary non-gestational extragonadal choriocarcinomas are uncommon and their head and neck localization more exceptional.


METHODS
We report on a primary choriocarcinoma case of the mandibular gingivae in a 26-year-old woman who presented with pulmonary and renal metastasis. Complete response (clinical, biological and radiological) was achieved with combined chemotherapy according to APE regimen associating actinomycin, cisplatin and etoposid. The patient was free of disease 4 years after therapy completion.


CONCLUSIONS
Primary gingival mandibular choriocarcinoma is very rare. Clinical presentation is atypical; diagnosis is based on histopathological examination and positivity for HCG. Our case report showed high chemo-sensitivity and comparable outcome to the other localizations.
Service d'Oncologie Médicale, CHU Habib-Bourguiba, 3029 Sfax, Tunisie. afefkhanfir@yahoo.fr
A
A
Khanfir
T
T
Kaffel
N
N
Gouiaa
T
T
Boudawara
M
M
Abdelmoula
M
M
Frikha
D000328:Adult; D031954:Choriocarcinoma, Non-gestational / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D005260:Female; D005887:Gingival Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D008441:Maxillary Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D011859:Radiography