Building an HIV data mashup using Bio2RDF.
We present an update to the Bio2RDF Linked Data Network, which now comprises ∼30 billion statements across 30 data sets. Significant changes to the framework include the accommodation of global mirrors, offline data processing and new search and integration services. The utility of this new network of knowledge is illustrated through a Bio2RDF-based mashup with microarray gene expression results and interaction data obtained from the HIV-1, Human Protein Interaction Database (HHPID) with respect to the infection of human macrophages with the human immunodeficiency virus type 1 (HIV-1).
Department of Biology, Carleton University, 1125 Colonel By Drive, Ottawa, Ontario, Canada K1S 5B6.
Marc-Alexandre
MA
Nolin
Michel
M
Dumontier
François
F
Belleau
Jacques
J
Corbeil
D019295:Computational Biology / Q000379:methods*; D030562:Databases, Protein; D015658:HIV Infections / Q000821:virology; D015497:HIV-1 / Q000235:genetics* / Q000378:metabolism; D006801:Humans; D008264:Macrophages / Q000821:virology; D046228:Microarray Analysis