Copper-catalyzed aerobic oxidative intramolecular C-H amination leading to imidazobenzimidazole derivatives.
A highly efficient copper-catalyzed aerobic oxidative intramolecular C-H amination has been developed using substituted 2-(1H-imidazol-1-yl)-N-alkylbenzenamines as the starting materials, and the corresponding imidazobenzimidazole derivatives were obtained in excellent yields. This is an economical and practical method for the construction of N-heterocycles.
Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University, Beijing 100084, PR China.
Xiaoqiang
X
Wang
Yunhe
Y
Jin
Yufen
Y
Zhao
Lin
L
Zhu
Hua
H
Fu
D000586:Amination; D001562:Benzimidazoles / Q000737:chemistry*; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D007093:Imidazoles / Q000737:chemistry*; D008958:Models, Molecular; D015394:Molecular Structure; D010084:Oxidation-Reduction
D001562:Benzimidazoles; D007093:Imidazoles; D003300:Copper; C029899:imidazole