Pediococcus acidilactici endocarditis successfully treated with daptomycin.
This report describes the first case of persistent bacteremia with endocarditis caused by Pediococcus acidilactici in a 32-year-old male with a history of short gut syndrome following a small bowel transplant. The results showed the utility of sequencing the intergenic spacer region for species identification and successful treatment using daptomycin.
Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, USA. piwen@unmc.edu
Peter C
PC
Iwen
Cezarina
C
Mindru
Andre C
AC
Kalil
Diana F
DF
Florescu
D000328:Adult; D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D016470:Bacteremia / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D004269:DNA, Bacterial / Q000737:chemistry / Q000235:genetics; D021903:DNA, Ribosomal Spacer / Q000737:chemistry / Q000235:genetics; D017576:Daptomycin / Q000008:administration & dosage*; D004697:Endocarditis, Bacterial / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D016908:Gram-Positive Bacterial Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D006801:Humans; D008297:Male; D008969:Molecular Sequence Data; D016377:Organ Transplantation / Q000009:adverse effects; D010376:Pediococcus / Q000145:classification / Q000302:isolation & purification*; D011183:Postoperative Complications / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D017422:Sequence Analysis, DNA; D016896:Treatment Outcome
D000900:Anti-Bacterial Agents; D004269:DNA, Bacterial; D021903:DNA, Ribosomal Spacer; D017576:Daptomycin