A case of propofol-induced oropharyngeal angioedema and bronchospasm.
Propofol (2,6-diisopropylphenol) is an ultrashort-acting sedative agent with sedative and amnestic effects that is used not only for anesthesia but also for sedation during minor outpatient procedures and endoscopic examinations. Rare cases of anaphylaxis following propofol administration have been reported in the medical literature. Documentation of anaphylaxis is often lacking because the cause and effect relationship is often hard to prove. Only a minority of patients get referred for allergy testing to confirm the offending drug. Here we report a 74-year-old woman who had an anaphylactic reaction with severe oropharyngeal edema and bronchospasm for a few minutes after receiving propofol during endoscopic examination. An allergy skin test was positive for both propofol and soybean. Soybean in the intralipid is one component of propofol, and we concluded that this anaphylaxis was caused by soybean.
Division of Allergy and Respiratory Medicine, Soonchunhyang University Bucheon Hospital, Bucheon, Korea.
Byung-Chul
BC
You
An-Soo
AS
Jang
Ji-Su
JS
Han
Hong-Woo
HW
Cheon
Jong-Suk
JS
Park
June-Hyuk
JH
Lee
Sung-Woo
SW
Park
Do-Jin
DJ
Kim
Choon-Sik
CS
Park