Reliability of a single objective measure in assessing sleepiness.
OBJECTIVE
To evaluate reliability of single objective tests in assessing sleepiness.


METHODS
Subjects who completed polysomnography underwent a 4-nap multiple sleep latency test (MSLT) the following day. Prior to each nap opportunity on MSLT, subjects performed the psychomotor vigilance test (PVT) and divided attention driving task (DADT). Results of single versus multiple test administrations were compared using the intraclass correlation coefficient (ICC) and adjusted for test administration order effects to explore time of day effects. Measures were explored as continuous and binary (i.e., impaired or not impaired).


METHODS
Community-based sample evaluated at a tertiary, university-based sleep center.


METHODS
372 adult commercial vehicle operators oversampled for increased obstructive sleep apnea risk.


METHODS
N/A.


RESULTS
AS CONTINUOUS MEASURES, ICC WERE AS FOLLOWS: MSLT 0.45, PVT median response time 0.69, PVT number of lapses 0.51, 10-min DADT tracking error 0.87, 20-min DADT tracking error 0.90. Based on binary outcomes, ICC were: MSLT 0.63, PVT number of lapses 0.85, 10-min DADT 0.95, 20-min DADT 0.96. Statistically significant time of day effects were seen in both the MSLT and PVT but not the DADT. Correlation between ESS and different objective tests was strongest for MSLT, range [-0.270 to -0.195] and persisted across all time points.


CONCLUSIONS
Single DADT and PVT administrations are reliable measures of sleepiness. A single MSLT administration can reasonably discriminate individuals with MSL < 8 minutes. These results support the use of a single administration of some objective tests of sleepiness when performed under controlled conditions in routine clinical care.
Department of Medicine, Division of Pulmonary and Critical Care, University of Pennsylvania, Philadelphia, PA 19104, USA. bernie.sunwoo@uphs.upenn.edu
Bernie Y
BY
Sunwoo
Nicholas
N
Jackson
Greg
G
Maislin
Indira
I
Gurubhagavatula
Charles F
CF
George
Allan I
AI
Pack
D001288:Attention / Q000502:physiology; D001334:Automobile Driving / Q000523:psychology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D017286:Polysomnography; D011597:Psychomotor Performance / Q000502:physiology; D015203:Reproducibility of Results; D012890:Sleep / Q000502:physiology; D014851:Wakefulness / Q000502:physiology*