F-18 FDG and C-11 methionine PET/CT in intracranial dural metastases.
A 58-year-old woman with breast carcinoma, after mastectomy, radiotherapy, and chemotherapy, underwent a whole-body F-18 FDG PET/CT for restaging, which revealed multiple skeletal metastasis. Hypometabolism was noted in the right frontal lobe. The patient subsequently underwent a C-11 methionine brain scan, which demonstrated multiple dural-based metastatic foci confirmed on contrast-enhanced MR. FDG PET has limitations in brain tumor detection. Amino acid tracers are particularly attractive for imaging of brain tumors because of relatively high tumor to brain activity ratios.
Division of PET Imaging, Molecular Imaging and Research Center, INMAS, Delhi, India. maria.md@rediffmail.com
Maria Mathew
MM
D'Souza
Abhinav
A
Jaimini
Madhavi
M
Tripathi
Naresh
N
Garg
Rajnish
R
Sharma
Anupam
A
Monndal
Rajendra P
RP
Tripathi
D001932:Brain Neoplasms / Q000000981:diagnostic imaging* / Q000556:secondary; D004388:Dura Mater / Q000000981:diagnostic imaging* / Q000473:pathology; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008577:Meningeal Neoplasms / Q000000981:diagnostic imaging* / Q000556:secondary*; D008715:Methionine; D008875:Middle Aged; D064847:Multimodal Imaging; D049268:Positron-Emission Tomography; D014057:Tomography, X-Ray Computed
D019788:Fluorodeoxyglucose F18; C086242:carbon-11 methionine; D008715:Methionine