Hashimoto's encephalopathy: systematic review of the literature and an additional case.
Hashimoto's encephalopathy, first described in 1966, is still problematic in terms of its pathophysiology, diagnosis, and treatment. The syndrome is more common in women, and is associated with autoimmune antithyroid antibodies. Presentation varies considerably; there may be episodes of cerebral ischemia, seizure, or psychosis, or there may be depression, cognitive decline, and periods of fluctuating consciousness. Because the symptoms respond so well to immunosuppressive treatment, prompt diagnosis and management are important. Here, the authors present a representative case report, along with a comprehensive review of current literature.
Agamenon Magalha˜es Hospital, Recife/PE, Brazil.
Narriane Chaves P
NC
de Holanda
Denise Dantas
DD
de Lima
Taciana Borges
TB
Cavalcanti
Cynthia Salgado
CS
Lucena
Francisco
F
Bandeira
D000818:Animals; D001927:Brain Diseases / Q000150:complications; D003072:Cognition Disorders; D016206:Databases, Bibliographic / Q000706:statistics & numerical data; D004660:Encephalitis; D005260:Female; D050031:Hashimoto Disease / Q000150:complications; D006801:Humans; D008569:Memory Disorders; D055815:Young Adult