Clinical outcome of twice-weekly hemodialysis patients in shanghai.
BACKGROUND
Twice-weekly hemodialysis (HD) is prevalent in the developing countries and the clinical outcome of this population remains to be elucidated.


METHODS
Data were collected from Shanghai Renal Registry. 2,572 patients undergoing regular HD in Shanghai on January 2007 were enrolled into the cohort study with 2 years' follow-up. Clinical and HD parameters obtained from the network were utilized to compare twice-weekly with thrice-weekly HD.


RESULTS
Compared with patients on thrice-weekly HD, the twice-weekly HD patients were significantly younger and had significantly longer HD session time, higher single-pool Kt/V (spKt/V) but shorter HD vintage (p < 0.001). Kaplan-Meier survival analysis indicated that the two groups had similar survival. Multivariate Cox regression analysis showed that age, body mass index, serum albumin and weekly Kt/V were predictors of patient mortality.


CONCLUSIONS
The similar survival between twice-weekly HD and thrice-weekly HD is likely relating to patient selection; dialysis adequacy of twice-weekly HD remains to be elucidated.
Renal Division, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, PR China.
Xinghui
X
Lin
Yucheng
Y
Yan
Zhaohui
Z
Ni
Leyi
L
Gu
Mingli
M
Zhu
Huili
H
Dai
Weiming
W
Zhang
Jiaqi
J
Qian
D000328:Adult; D000368:Aged; D002681:China; D015331:Cohort Studies; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007676:Kidney Failure, Chronic / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis / Q000379:methods*; D016019:Survival Analysis; D016896:Treatment Outcome