NHC-catalyzed thioesterification of aldehydes by external redox activation.
The NHC-catalyzed thioesterification of aromatic or aliphatic aldehydes with a range of thiols was developed in the presence of a stoichiometric amount of an organic oxidant. Among the oxidants examined, phenazine was shown to give the best results in terms of chemical yield and compatibility with thiols.
Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto, 606-8501, Japan.
Takuya
T
Uno
Tsubasa
T
Inokuma
Yoshiji
Y
Takemoto
D000447:Aldehydes / Q000737:chemistry*; D002384:Catalysis; D004951:Esterification; D008697:Methane / Q000031:analogs & derivatives* / Q000737:chemistry; D016877:Oxidants / Q000737:chemistry*; D010084:Oxidation-Reduction; D010619:Phenazines / Q000737:chemistry*
D000447:Aldehydes; D016877:Oxidants; D010619:Phenazines; C030011:carbene; D008697:Methane