[Metabolic syndrome in children and adolescents: doubts about terminology but not about cardiometabolic risks].
Metabolic syndrome (MS) has been a condition involved in considerable controversy, starting with the terminology. Gerald Reaven himself, the author who proposed the term MS, advised against the use of this terminology because the definition implies in at least three metabolic alterations, and it is never clear to which group of alterations we are referring to when we say that a patient has MS. In children, the problem is even more complicated, since there are many different adaptations to the criteria used in adults. On the other hand, independent of the terminology, cardiovascular risks are well-established and it is very clear that even children may present metabolic disturbances which predict future metabolic problems. The role of the pediatric endocrinologist or the general pediatrician is to investigate, especially in overweight/obese children, conditions that if treated early, may prevent future complications that today, unfortunately, are being diagnosed only in adult life. In this review, we discuss problems on the definition, epidemiology, pathophysiology, and complications of MS in children and adolescents.
Unidade de Endocrinologia Pediátrica, Instituto da Criança, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, Brasil. durvald@iconet.com.br
Durval
D
Damiani
Valesca Mansur
VM
Kuba
Louise
L
Cominato
Daniel
D
Damiani
Vaê
V
Dichtchekenian
Hamilton Cabral de
HC
Menezes Filho
D000293:Adolescent; D002318:Cardiovascular Diseases / Q000209:etiology*; D002648:Child; D006801:Humans; D024821:Metabolic Syndrome / Q000150:complications* / Q000175:diagnosis / Q000453:epidemiology; D009765:Obesity / Q000453:epidemiology; D012307:Risk Factors; D009626:Terminology as Topic