Possible vitreous involvement in a case with rapidly progressing choroidal neovascularization.
A 65-year-old man with subfoveal choroidal neovascularization (CNV) underwent photodynamic therapy (PDT). Despite the sequential treatments, the CNV grew larger and finally penetrated the retina. Vitreous adhesion was observed at the edge of the supraretinal fibrotic tissue. The case highlighted the possible unexpected side-effect of PDT. The upregulation of the vascular endothelial growth factor or the enhanced vitreous traction was considered to be responsible for the event.
Department of Ophthalmology, Kobe City Medical Center General Hospital, Kobe, Japan.
Masayuki
M
Hata
Akio
A
Oishi
Michiko
M
Mandai
Yasuo
Y
Kurimoto
D000368:Aged; D020256:Choroidal Neovascularization / Q000188:drug therapy / Q000209:etiology / Q000473:pathology*; D018450:Disease Progression; D005451:Fluorescein Angiography; D005500:Follow-Up Studies; D005654:Fundus Oculi; D006801:Humans; D008268:Macular Degeneration / Q000150:complications / Q000188:drug therapy / Q000473:pathology; D008297:Male; D010778:Photochemotherapy; D017319:Photosensitizing Agents / Q000627:therapeutic use; D011166:Porphyrins / Q000627:therapeutic use; D014792:Visual Acuity; D014822:Vitreous Body / Q000473:pathology*
D017319:Photosensitizing Agents; D011166:Porphyrins