Famous people knowledge and the right and left temporal lobes.
It is generally accepted that the anterior temporal lobes support knowledge of famous people. The specific roles of the right and left temporal lobe remain a subject of debate, with some studies suggesting differential roles based on modality (visual versus verbal information) and others category (person knowledge versus general semantics). The present study re-examined performance of semantic dementia patients with predominantly right and predominantly left temporal lobe atrophy on famous face, famous name and general semantic tasks, with the specific aim of testing the hypothesis that the right temporal lobe has a privileged role for person knowledge and the left temporal lobe for general semantic knowledge. Comparisons of performance rankings across tasks showed no evidence to support this hypothesis. By contrast, there was robust evidence from naming, identification and familiarity measures for modality effects: right-sided atrophy being associated with relatively greater impairment for faces and visual tasks and left-sided atrophy for names and verbal tasks. A double dissociation in test scores in two patients reinforced these findings. The data present a challenge for the influential `semantic hub' model, which views the anterior temporal lobes as an area of convergence in which semantic information is represented in amodal form.
Cerebral Function Unit, Greater Manchester Neuroscience Centre, Salford Royal Foundation Trust, Salford, UK. julie.snowden@manchester.ac.uk
Julie S
JS
Snowden
Jennifer C
JC
Thompson
David
D
Neary
D000368:Aged; D001284:Atrophy / Q000473:pathology; D001307:Auditory Perception; D005145:Face; D005260:Female; D057174:Frontotemporal Lobar Degeneration / Q000523:psychology*; D007839:Functional Laterality; D006801:Humans; D008297:Male; D009275:Names; D009483:Neuropsychological Tests / Q000706:statistics & numerical data; D011597:Psychomotor Performance; D021641:Recognition, Psychology; D012660:Semantics; D013702:Temporal Lobe / Q000473:pathology*; D014796:Visual Perception