Ruthenium catalyzed synthesis of enaminones.
The Grubbs first-generation catalyst has been found to be an effective catalyst for the synthesis of enaminones by coupling thioamides with α-diazodicarbonyl compounds. The reaction is successful in converting primary, secondary, and tertiary thioamides into their corresponding enaminones. The reaction is also suitable for the synthesis of chiral enaminones.
Department of Chemistry and Biochemistry, The University of Tulsa, Keplinger Hall, 800 South Tucker Drive, Tulsa, Oklahoma 74101, USA.
Naga Durgarao
ND
Koduri
Halee
H
Scott
Bethany
B
Hileman
Justin D
JD
Cox
Michael
M
Coffin
Lindsay
L
Glicksberg
Syed R
SR
Hussaini