Identification of two voltage-dependent anion channel-like protein sequences conserved in Kinetoplastida.
The eukaryotic porin superfamily consists of two families, voltage-dependent anion channel (VDAC) and Tom40, which are both located in the mitochondrial outer membrane. In Trypanosoma brucei, only a single member of the VDAC family has been described. We report the detection of two additional eukaryotic porin-like sequences in T. brucei. By bioinformatic means, we classify both as putative VDAC isoforms.
Department of Biosciences, Molecular Cell Biology of Plants, Goethe University Frankfurt, Frankfurt, Hesse, Germany.
Nadine
N
Flinner
Enrico
E
Schleiff
Oliver
O
Mirus
D000595:Amino Acid Sequence; D008969:Molecular Sequence Data; D015800:Protozoan Proteins / Q000235:genetics* / Q000378:metabolism; D017384:Sequence Deletion; D014346:Trypanosoma brucei brucei / Q000737:chemistry / Q000235:genetics*; D050994:Voltage-Dependent Anion Channels / Q000235:genetics* / Q000378:metabolism
D015800:Protozoan Proteins; D050994:Voltage-Dependent Anion Channels