Palladium-catalyzed cascade cyclization-oxidative olefination of tert-butyl 2-alkynylbenozates.
Palladium(II) can catalyze the oxidative coupling of tert-butyl 2-alkynylbenzoates with olefins such as acrylates and styrenes, leading to isocoumarines. The reaction was carried out under simple aerobic conditions, and in most cases, high selectivity has been attained.
Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China.
Peng
P
Zhao
Dan
D
Chen
Guoyong
G
Song
Keli
K
Han
Xingwei
X
Li