De novo translocation t(5;9)(q11.2;p22) associated with hydrops fetalis and cystic hygroma.
We report on a case of a prenatally diagnosed non-immune hydrops fetalis and cystic hygroma associated with the balanced translocation t(5;9)(q11.2;p22), an association that to our knowledge has not been reported previously. Both parents had normal karyotypes. The infant was born prematurely at 33 and 3/7 weeks gestation and expired 12 h after delivery.
Department of Anatomy, Cell Biology and Pathology, University of South Florida, Tampa, Florida 33606, USA.
Kristen
K
Eisbrenner
Thora S
TS
Steffensen
Valerie E
VE
Whiteman
Enid
E
Gilbert-Barness
D000328:Adult; D002895:Chromosomes, Human, Pair 5 / Q000235:genetics*; D002899:Chromosomes, Human, Pair 9 / Q000235:genetics*; D005260:Female; D006801:Humans; D015160:Hydrops Fetalis / Q000235:genetics* / Q000473:pathology; D007231:Infant, Newborn; D018191:Lymphangioma, Cystic / Q000235:genetics* / Q000473:pathology; D011247:Pregnancy; D011248:Pregnancy Complications / Q000235:genetics* / Q000473:pathology; D011296:Prenatal Diagnosis; D014178:Translocation, Genetic