The determinants of 2009 pandemic A/H1N1 influenza vaccination: a systematic review.
BACKGROUND
Pandemic A/H1N1 influenza vaccine coverage varied widely across countries. To understand the factors influencing pandemic influenza vaccination and to guide the development of successful vaccination programs for future influenza pandemics, we identified and summarized studies examining the determinants of vaccination during the 2009 influenza pandemic.


METHODS
We performed a systematic literature review using the PubMED electronic database from June 2009 to February 2011. We included studies examining an association between a possible predictive variable and actual receipt of the pandemic A/H1N1 influenza vaccine. We excluded studies examining intention or willingness to receive the vaccine.


RESULTS
Twenty-seven studies were identified from twelve countries. Pandemic influenza vaccine coverage varied from 4.8% to 92%. Coverage varied by population sub-group, country, and assessment method used. Most studies used questionnaires to estimate vaccine coverage, however seven (26%) used a vaccination registry. Factors that positively influenced pandemic influenza vaccination were: male sex, younger age, higher education, being a doctor, being in a priority group for which vaccination was recommended, receiving a prior seasonal influenza vaccination, believing the vaccine to be safe and/or effective, and obtaining information from official medical sources.


CONCLUSIONS
Vaccine coverage during the pandemic varied widely across countries and population sub-groups. We identified some consistent determinants of this variation that can be targeted to increase vaccination during future influenza pandemics.
Surveillance Lab, McGill Clinical and Health Informatics, McGill University, 1140 Pine Avenue West, Montreal, Canada H3A 1A3.
Stephanie
S
Brien
Jeffrey C
JC
Kwong
David L
DL
Buckeridge
D000328:Adult; D000367:Age Factors; D001208:Asia / Q000453:epidemiology; D001291:Attitude of Health Personnel; D001315:Australia / Q000453:epidemiology; D002648:Child; D004522:Educational Status; D005060:Europe / Q000453:epidemiology; D005260:Female; D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype / Q000276:immunology*; D007252:Influenza Vaccines; D007251:Influenza, Human / Q000453:epidemiology / Q000517:prevention & control*; D008297:Male; D058873:Pandemics; D010342:Patient Acceptance of Health Care; D011247:Pregnancy; D012042:Registries; D011795:Surveys and Questionnaires; D014481:United States / Q000453:epidemiology; D014611:Vaccination
D007252:Influenza Vaccines