Long-term follow-up of intravitreal bevacizumab in retinal arterial macroaneurysm: a case report.
OBJECTIVE
To present the long-term effect of intravitreal bevacizumab (Avastin(®)) therapy in a patient suffering from retinal arterial macroaneurysm.


METHODS
Case report of a 72-year-old female diagnosed with retinal macroaneurysm in the superior temporal artery leading to macular edema. Functional and morphological data at baseline, 4 weeks, 2 months, and 13 months following treatment with two consecutive intravitreal bevacizumab injections are presented.


RESULTS
Best-corrected visual acuity improved from 20/160 at baseline to 20/20 at the 3-months follow-up and remained stable through 13 months of follow-up. Central retinal thickness measured by optical coherence tomography decreased from 364 μm at baseline to 248 μm at the 13-months follow-up. No ocular or systemic side effects were detected.


CONCLUSIONS
Intravitreal bevacizumab therapy may lead to resolution of macular edema associated with retinal macroaneurysm and consequently visual improvement. This treatment may promise a long-lasting effect but warrant further investigation in larger series.
Department of Ophthalmology, Tel Aviv Sourasky Medical Center, Tel Aviv University, Tel-Aviv, Israel.
Shani
S
Golan
Daphna
D
Goldenberg
Michaella
M
Goldstein