Infectious agents associated with respiratory diseases in 125 farrow-to-finish pig herds: a cross-sectional study.
A study was carried out in 125 farrow-to-finish pig herds to assess the relationships between pathogens involved in respiratory disorders and to relate these findings to clinical signs of respiratory diseases and pneumonia and pleuritis at slaughter. Clinical examination and sampling were carried out on four different batches in each herd (pigs aged 4, 10, 16 and 22 weeks). Mycoplasma hyopneumoniae, Actinobacillus pleuropneumoniae, swine influenza viruses (SIV), porcine reproductive and respiratory syndrome virus (PRRSV) and porcine circovirus type 2 (PCV2) were detected by serological or PCR tests. Pneumonia-like gross lesions and pleuritis were scored at the slaughterhouse. The results indicate that the percentage of pigs PCR-positive for PCV2 at 4, 10 and 16 weeks old was associated with the percentage of pigs PCR-positive for M. hyopneumoniae at these ages. On the other hand, the percentage of pigs with antibodies against PRRSV at 10, 16 and 22 weeks was positively correlated with the percentage of pigs seropositive for M. hyopneumoniae at 22 weeks, with the percentage of pigs with antibodies against SIV H1N1 and SIV H1N2 and the percentage of pigs sero-positive for A. pleuropneumoniae serotype 2. The findings also indicate that, within the five studied pathogens, M. hyopneumoniae, PRRSV and SIV H1N1 are the major pathogens involved in pneumonia-like gross lesions even though PCV2 may play a role. A. pleuropneumoniae serotype 2, in association with PRRSV, is significantly associated with extensive pleuritis. Respiratory diseases could be significantly reduced by implementing measures including appropriate management practices to control these pathogens.
Agence Nationale de Sécurité Sanitaire (Anses), Unité Epidémiologie et Bien-Etre du Porc, B.P. 53, 22440 Ploufragan, France. christelle.fablet@anses.fr
C
C
Fablet
C
C
Marois-Créhan
G
G
Simon
B
B
Grasland
A
A
Jestin
M
M
Kobisch
F
F
Madec
N
N
Rose
D000189:Actinobacillus Infections / Q000175:diagnosis / Q000453:epidemiology / Q000662:veterinary; D016977:Actinobacillus pleuropneumoniae / Q000302:isolation & purification*; D000818:Animals; D000907:Antibodies, Bacterial / Q000097:blood; D000914:Antibodies, Viral / Q000097:blood; D018173:Circoviridae Infections / Q000175:diagnosis / Q000453:epidemiology / Q000662:veterinary; D017925:Circovirus / Q000302:isolation & purification*; D003430:Cross-Sectional Studies; D005602:France / Q000453:epidemiology; D053118:Influenza A Virus, H1N1 Subtype / Q000302:isolation & purification*; D057221:Influenza A Virus, H1N2 Subtype; D045705:Mycoplasma hyopneumoniae / Q000302:isolation & purification*; D009976:Orthomyxoviridae Infections / Q000175:diagnosis / Q000453:epidemiology / Q000662:veterinary; D010998:Pleurisy / Q000453:epidemiology / Q000382:microbiology / Q000662:veterinary / Q000821:virology; D011001:Pleuropneumonia / Q000453:epidemiology / Q000382:microbiology / Q000662:veterinary / Q000821:virology; D019318:Porcine Reproductive and Respiratory Syndrome / Q000175:diagnosis / Q000453:epidemiology; D019316:Porcine respiratory and reproductive syndrome virus / Q000302:isolation & purification*; D034421:Sus scrofa / Q000382:microbiology / Q000821:virology; D013552:Swine; D013553:Swine Diseases / Q000175:diagnosis / Q000453:epidemiology / Q000382:microbiology* / Q000821:virology*
D000907:Antibodies, Bacterial; D000914:Antibodies, Viral