The effectiveness of glucose in reducing needle-related procedural pain in infants.
This systematic review examined the effectiveness of glucose in relieving needle-associated pain in infants. Meta-analysis was not undertaken, and there was variation in dose, administration method, concentration, and outcome measurement. Glucose was more effective than placebo in relieving infant pain as measured by behavioral outcomes, but there were mixed findings for physiological outcomes. Based on these findings, 25%-50% glucose appears effective for infant pain management.
Faculty of Nursing, Midwifery and Health, University of Technology, Sydney, Australia. manal_kassab@yahoo.com
Manal Ibrahim
MI
Kassab
Jessica K
JK
Roydhouse
Cathrine
C
Fowler
Maralyn
M
Foureur
D005947:Glucose / Q000008:administration & dosage*; D006801:Humans; D007223:Infant; D009339:Needles; D010146:Pain / Q000517:prevention & control*; D011677:Punctures / Q000009:adverse effects*; D016032:Randomized Controlled Trials as Topic; D013549:Sweetening Agents / Q000008:administration & dosage*
D013549:Sweetening Agents; D005947:Glucose