Risk assessment of chlorpyrifos on rice and cabbage in China.
Chlorpyrifos is a widely used organophosphorus insecticide in agricultural pest control. To understand the residue behavior of chlorpyrifos and to evaluate the dietary risk of chlorpyrifos residue in food in China, a number of residue studies were conducted on rice and cabbage. The supervised trial median residues (STMRs) for rice and cabbage were less than 0.010 and 0.227 mg kg⁻¹, respectively. Only 7.4% and 13.3% of acceptable daily intake (ADI) (0-0.01 mg kg⁻¹ bw) of chlorpyrifos is occupied by dietary daily intake to the Chinese adult and children, respectively, due to the consumption of rice and cabbage. These results on risk assessment were consistent with that of JMPR. Incorporation of market survey residue data gave a 5-fold reduction in the estimated exposures to chlorpyrifos. Concerning the acute exposure, the national estimated short-term intake (NESTI) represents 0.077% and 10.6% for rice and cabbage, respectively, of the acute reference dose (ARfD) (0-0.1 mg kg⁻¹ bw). The application of chlorpyrifos at the recommended dose on rice and cabbage is unlikely to pose any public health issues if it is applied according to the good agricultural practices (GAPs) established by each country.
Key Lab of Agro-product Quality and Safety, Institute of Quality Standards & Testing Technology for Agro-Products, Chinese Academy of Agricultural Sciences, Beijing 100081, People's Republic of China.
Chen
C
Chen
Yongzhong
Y
Qian
Xianjin
X
Liu
Chuanjiang
C
Tao
Ying
Y
Liang
Yun
Y
Li
D000328:Adult; D000818:Animals; D001937:Brassica; D002648:Child; D002681:China; D004390:Chlorpyrifos / Q000032:analysis* / Q000633:toxicity; D002800:Cholinesterase Inhibitors / Q000032:analysis* / Q000633:toxicity; D004781:Environmental Exposure / Q000009:adverse effects / Q000032:analysis; D005506:Food Contamination / Q000032:analysis; D006801:Humans; D007306:Insecticides / Q000032:analysis* / Q000633:toxicity; D012275:Oryza; D010573:Pesticide Residues / Q000032:analysis* / Q000633:toxicity; D018570:Risk Assessment
D002800:Cholinesterase Inhibitors; D007306:Insecticides; D010573:Pesticide Residues; D004390:Chlorpyrifos