BIOCLAIMS standard diet (BIOsd): a reference diet for nutritional physiology.
Experimental replication is fundamental for practicing science. To reduce variability, it is essential to control sources of variation as much as possible. Diet is an important factor that can influence many processes and functional outcomes in studies performed with rodent models. This is especially true for, but not limited to, nutritional studies. To compare functional effects of different nutrients, it is important to use standardized, semi-purified diets. Here, we propose and describe a standard reference diet, the BIOCLAIMS standard diet. The diet is AIN-93 based, but further defined with dietary and experimental requirements taken into account that allow for experiments with bioactive food components and natural (non-expensive) labeling. This diet will be implemented by two European research consortia, Mitofood and BIOCLAIMS, to ensure inter-laboratory comparability.
Department of Human and Animal Physiology, Wageningen University, Wageningen, The Netherlands.
Femke P M
FP
Hoevenaars
Evert M
EM
van Schothorst
Olga
O
Horakova
Anja
A
Voigt
Martin
M
Rossmeisl
Catalina
C
Pico
Antoni
A
Caimari
Jan
J
Kopecky
Susanne
S
Klaus
Jaap
J
Keijer