Leptospirosis presenting as ascending progressive leg weakness and complicating with acute pancreatitis.
Leptospirosis is a spirochetal bacterial infection of great public health importance. It has a broad spectrum of clinical manifestations which goes from subclinical infection and self-limited anicteric febrile illness (80-90% of all cases) to icteric leptospiropirosis known as Weil's disease. This is a severe disease characterized by hemorrhage, acute renal failure and jaundice. It is uncommon for leptospirosis to present itself as a primary neurological disease. Additionally, acute pancreatitis is an unusual gastrointestinal manifestation. We report a case of leptospirosis presenting as ascending progressive leg weakness and complicating with acute pancreatitis in an adult patient treated at Hospital Universitário, Universidade Federal de Santa Catarina. The diagnosis was confirmed through ELISA-IgM antibody testing positive for leptospirosis. After antibiotic therapy and support treatment for a few weeks, total resolution of severe manifestations was achieved. Rare and unusual presentations of leptospirosis should be kept in mind in relevant epidemiological scenario.
Hospital Universitário, Departamento de ClínicaMédica, Universidade Federal de Santa Catarina, SC, Brazil. andreps_garopaba@yahoo.com.br
Andre Pacheco
AP
Silva
Luciana Bonnassis
LB
Burg
João Felipe Schadeck
JF
Locatelli
Joice
J
Manes
Morgana
M
Crispim
D000208:Acute Disease; D006801:Humans; D007866:Leg; D007922:Leptospirosis / Q000150:complications* / Q000175:diagnosis; D008297:Male; D008875:Middle Aged; D018908:Muscle Weakness / Q000209:etiology*; D010195:Pancreatitis / Q000209:etiology*; D010523:Peripheral Nervous System Diseases / Q000209:etiology*