Modulation of the translocation of peptides through nanopores by the application of an AC electric field.
The interaction of two peptides with the α-hemolysin pore was studied in the presence of a MHz AC field. For an α-helical peptide the proportion of bumping events increased with increasing AC field whereas for a linear peptide with no dipole moment only small changes in the event profiles were observed.
Department of Biochemistry, 107 Wiggins Road University of Saskatchewan, Saskatoon, Canada.
Radu I
RI
Stefureac
Anton
A
Kachayev
Jeremy S
JS
Lee
D000595:Amino Acid Sequence; D004560:Electricity; D006460:Hemolysin Proteins / Q000378:metabolism*; D008969:Molecular Sequence Data; D058608:Nanopores; D010455:Peptides / Q000737:chemistry / Q000378:metabolism*; D021381:Protein Transport
D006460:Hemolysin Proteins; D010455:Peptides