Antidepressants in chronic idiopathic urticaria.
Chronic idiopathic urticaria (CIU) is a common disease estimated to affect 0.1% of the population and can be very difficult to treat. Many psychotropic medications have been reported to be successful in treating refractory CIU. The purpose of this article was to discuss the pathophysiology of chronic urticaria and provide practicing allergists and dermatologists alternative treatment options in the management of refractory CIU, especially in those who have concurrent psychiatric comorbidity. A review was performed of pertinent literature pertaining to the pathophysiology of CIU and the many psychotropic medications reportedly successful in disease management. Although more research is needed, this article serves to broaden the mind of the physician treating CIU.
Department of Medicine, Cedars Sinai Medical Center, Los Angeles, California, USA. myasharp@uci.edu
Michelle R
MR
Yasharpour
Inderpal
I
Randhawa
D000928:Antidepressive Agents / Q000627:therapeutic use*; D002908:Chronic Disease; D015897:Comorbidity; D006801:Humans; D014581:Urticaria / Q000188:drug therapy* / Q000453:epidemiology / Q000209:etiology
D000928:Antidepressive Agents