Study on the occurrence and neural bases of hemispatial neglect with different reference frames.
OBJECTIVE
To study the distributions and the neural correlates of left hemispatial neglect with different reference frames.


METHODS
Data were collected from patients with right brain injury who participated in a case series.


METHODS
Hospital departments of rehabilitation and neurology.


METHODS
Right brain-damaged patients (N=110).


METHODS
Not applicable.


METHODS
The frequency of left hemispatial neglect with different reference frames was investigated, and the respective brain lesions were displayed and analyzed.


RESULTS
Not all subjects finished predesigned neglect tests because of their condition: 8 of the 55 neglect patients were unable to complete the test for classification. Thirty (63.83%) of 47 subjects with neglect displayed both allocentric and egocentric neglect, while 17 subjects showed pure egocentric neglect. The lesions in the inferior frontal gyrus, precentral gyrus, postcentral gyrus, superior temporal gyrus (STG), middle temporal gyrus (MTG), insula, and surrounding white matters were more frequent in the neglect group than in the control group. Compared with the egocentric neglect group, the lesions in the right STG, MTG, lenticular nucleus, and the surrounding white matter were damaged more frequently in the group displaying both allocentric and egocentric neglect.


CONCLUSIONS
More than half of the subjects with left neglect after right brain injury have both egocentric and allocentric neglect. The right inferior frontal gyrus, precentral gyrus, postcentral gyrus, STG, MTG, insula, and the surrounding white matter are associated with left hemispatial neglect. Left allocentric neglect is associated with the right STG, MTG, and lenticular nucleus.
Department of Rehabilitation, Xuanwu Hospital, Capital Medical University, Beijing, China.
Yuehong
Y
Yue
Weiqun
W
Song
Su
S
Huo
Maobin
M
Wang
D000368:Aged; D001930:Brain Injuries / Q000150:complications* / Q000175:diagnosis; D001931:Brain Mapping / Q000379:methods; D016022:Case-Control Studies; D004569:Electroencephalography / Q000379:methods; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D010296:Parietal Lobe / Q000473:pathology; D010468:Perceptual Disorders / Q000175:diagnosis* / Q000453:epidemiology* / Q000209:etiology; D011597:Psychomotor Performance / Q000502:physiology; D012016:Reference Values; D018570:Risk Assessment; D012720:Severity of Illness Index; D013028:Space Perception / Q000502:physiology; D020521:Stroke / Q000150:complications* / Q000175:diagnosis; D013702:Temporal Lobe / Q000473:pathology; D013997:Time Factors; D016896:Treatment Outcome