Iterative Development of an Application to Support Nuclear Magnetic Resonance Data Analysis of Proteins.
The CONNecticut Joint University Research (CONNJUR) team is a group of biochemical and software engineering researchers at multiple institutions. The vision of the team is to develop a comprehensive application that integrates a variety of existing analysis tools with workflow and data management to support the process of protein structure determination using Nuclear Magnetic Resonance (NMR). The use of multiple disparate tools and lack of data management, currently the norm in NMR data processing, provides strong motivation for such an integrated environment. This manuscript briefly describes the domain of NMR as used for protein structure determination and explains the formation of the CONNJUR team and its operation in developing the CONNJUR application. The manuscript also describes the evolution of the CONNJUR application through four prototypes and describes the challenges faced while developing the CONNJUR application and how those challenges were met.
Western New England College, 1215 Wilbraham Road Springfield, MA 01119.
Heidi J C
HJ
Ellis
Ronald J
RJ
Nowling
Jay
J
Vyas
Timothy O
TO
Martyn
Michael R
MR
Gryk