[Detection and management of non-motor symptoms in Parkinson's disease: impact on their prevalence].
BACKGROUND
Non-motor symptoms are common among patients with Parkinson disease and include cognitive, psychiatric, sleep and autonomic dysfunctions.


OBJECTIVE
To determine if the detection of non-motor symptoms along with the appropriate referral to an specialist has an impact on their prevalence after one year follow-up.


METHODS
We included 60 patients diagnosed with Parkinson's disease attending to the Movement Disorder Clinic. The presence of non-motor symptoms was determined by the non-motor symptom questionnaire (NMSQuest).


RESULTS
The mean NMSQuest scores at baseline and at one year follow up were 12.6 ± 6.2 and 9.9 ± 5.6, respectively (p < 0.01). The non-motor symptoms that showed a statistically significant differences in frequency between baseline and the final assessment, were constipation (p = 0.04), urinary urgency (p = 0.02), hallucinations (p = 0.04), dizziness (p = 0.02) and vivid dreams (p = 0.04).


CONCLUSIONS
Intentional search for non-motor symptoms in patients with Parkinson's disease along with a multidisciplinary approach has an impact on their prevalence. The change in specific symptoms is probably related to adjustments in dopaminergic management.
Laboratorio Clínico de Enfermedades Neurodegenerativas, Instituto Nacional de Neurología y Neurocirugía, Tlalpan, México. mrodriguez@innn.edu.mx
Mayela
M
Rodríguez-Violante
Amin
A
Cervantes-Arriaga
D000368:Aged; D004298:Dopamine / Q000008:administration & dosage*; D015259:Dopamine Agents / Q000008:administration & dosage*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D009043:Motor Activity / Q000187:drug effects; D009069:Movement Disorders / Q000175:diagnosis / Q000453:epidemiology*; D010300:Parkinson Disease / Q000150:complications* / Q000188:drug therapy; D011795:Surveys and Questionnaires / Q000592:standards
D015259:Dopamine Agents; D004298:Dopamine