A benzopyrane derivative as a P-glycoprotein stimulator: a potential agent to decrease β-amyloid accumulation in Alzheimer's disease.
Dipartimento Farmacochimico, Università degli Studi di Bari "A. Moro", Via Orabona 4, 70125 Bari, Italy. contino@farmchim.uniba.it
Marialessandra
M
Contino
Mariangela
M
Cantore
Elena
E
Capparelli
Maria Grazia
MG
Perrone
Mauro
M
Niso
Carmela
C
Inglese
Francesco
F
Berardi
Marcello
M
Leopoldo
Roberto
R
Perrone
Nicola Antonio
NA
Colabufo
D020168:ATP Binding Cassette Transporter, Subfamily B, Member 1 / Q000819:agonists* / Q000378:metabolism; D000544:Alzheimer Disease / Q000188:drug therapy* / Q000378:metabolism; D016229:Amyloid beta-Peptides / Q000378:metabolism*; D000818:Animals; D001578:Benzopyrans / Q000138:chemical synthesis / Q000494:pharmacology* / Q000627:therapeutic use; D001693:Biological Transport, Active / Q000187:drug effects; D001921:Brain / Q000187:drug effects / Q000378:metabolism; D002460:Cell Line; D004285:Dogs; D004305:Dose-Response Relationship, Drug; D005452:Fluoresceins; D005456:Fluorescent Dyes; D006801:Humans; D057927:Hydrophobic and Hydrophilic Interactions; D007700:Kinetics; D027425:ATP-Binding Cassette, Sub-Family C Proteins / Q000037:antagonists & inhibitors / Q000378:metabolism; D018696:Neuroprotective Agents / Q000138:chemical synthesis / Q000494:pharmacology* / Q000627:therapeutic use; D012235:Rhodamines
D020168:ATP Binding Cassette Transporter, Subfamily B, Member 1; D016229:Amyloid beta-Peptides; D001578:Benzopyrans; D005452:Fluoresceins; D005456:Fluorescent Dyes; D027425:ATP-Binding Cassette, Sub-Family C Proteins; D018696:Neuroprotective Agents; D012235:Rhodamines; C007740:fluorexon; C421109:multidrug resistance-associated protein 1