A label-free electrochemical assay for quantification of gene-specific methylation in a nucleic acid sequence.
A label-free electrochemical method is developed for simple and convenient quantification of gene-specific DNA hypermethylation in a DNA sequence without PCR amplification, bisulfite conversion or labeling processes.
School of Chemistry and Chemical Engineering, Sun Yat-Sen University, Guangzhou 510275, PR China. daizong@mail.sysu.edu.cn
Zong
Z
Dai
Xiao
X
Hu
Hai
H
Wu
Xiaoyong
X
Zou
D001483:Base Sequence; D015374:Biosensing Techniques / Q000379:methods*; D004247:DNA / Q000737:chemistry*; D019175:DNA Methylation; D055664:Electrochemical Techniques / Q000379:methods*; D009693:Nucleic Acid Hybridization / Q000379:methods; D012680:Sensitivity and Specificity
D004247:DNA