Hepatocellular carcinoma in 2011 and beyond: from the pathogenesis to molecular targeted therapy.
Hepatocellular carcinoma is a malignant tumor responsible for approximately 600,000-700,000 deaths worldwide, and it is becoming more prevalent not only in Southeast Asia and Africa but also in Western countries; therefore, interest in hepatocellular carcinoma has mounted in recent years in the West, where little or no interest was evident 10-20 years ago.
Department of Gastroenterology and Hepatology, Kinki University School of Medicine, Ohno-Higashi, Osakasayama, Japan. m-kudo@med.kindai.ac.jp
Masatoshi
M
Kudo
D014408:Biomarkers, Tumor; D006528:Carcinoma, Hepatocellular / Q000175:diagnosis / Q000209:etiology / Q000517:prevention & control / Q000628:therapy; D016174:Hepacivirus / Q000472:pathogenicity; D006801:Humans; D008113:Liver Neoplasms / Q000209:etiology / Q000473:pathology / Q000517:prevention & control / Q000628:therapy; D058990:Molecular Targeted Therapy / Q000379:methods*; D017382:Reactive Oxygen Species / Q000378:metabolism; D015398:Signal Transduction
D014408:Biomarkers, Tumor; D017382:Reactive Oxygen Species