[Catastrophic primary antiphospholipid syndrome].
Catastrophic antiphospholipid syndrome develops in a minority of patients with antiphospholipid syndrome, and is characterized by acute thrombotic microvasculopathy with multiorganic involvement (three or more organs). The aetiology is unknown, the diagnosis is complex, and the treatment is empiric, mortality may approach 50%. The authors present a clinical case of catastrophic antiphospholipid syndrome, diagnosed in a patient with abdominal pain and severe respiratory failure.
Serviços de Medicina Intensiva e Anatomia Patológica, Hospitais da Universidade de Coimbra, Coimbra.
Paula
P
Casanova
João P
JP
Baptista
Maria J
MJ
Andrade
Paulo
P
Martins
J P
JP
Almeida Sousa
Victor
V
Fernandes
Armindo
A
Simões
Júlio
J
Souto Gonçalves
Janeiro
J
Costa
Armindo
A
Rebelo
Lina
L
Carvalho
Jorge
J
Pimentel
D016736:Antiphospholipid Syndrome / Q000175:diagnosis*; D002388:Catastrophic Illness; D005260:Female; D006801:Humans; D055815:Young Adult