[Hereditary angioedema: a therapeutic revolution].
Hereditary angioedema is a rare disease, often diagnosed with delay because of a heterogeneous clinical presentation. Before diagnosis, patients frequently present subcutaneous edema or abdominal pains during many years. Laryngeal edema can be life-threatening. Hereditary angioedema may impair the quality of life of the patients and their social and professional life. It is important that the physicians recognize and treat the disease as soon as possible after the first attacks. Since the past five years, new drugs developed for hereditary angioedema have changed dramatically the outcome of this disorder. The objective of this review is to detail the new therapeutic guidelines.
Centre de référence des angiœdèmes (CREAK), clinique universitaire de médecine interne, CHU de Grenoble, BP 217, Grenoble cedex 09, France. lbouillet@chu-grenoble.fr
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D054179:Angioedemas, Hereditary / Q000150:complications / Q000175:diagnosis / Q000628:therapy*; D004059:Diffusion of Innovation; D006801:Humans; D007388:Internal Medicine / Q000379:methods / Q000639:trends*; D008954:Models, Biological; D011315:Preventive Medicine / Q000379:methods; D035583:Rare Diseases / Q000175:diagnosis / Q000628:therapy; D035703:Therapies, Investigational / Q000379:methods / Q000639:trends