Biomechanical characterisation of a degradable magnesium-based (MgCa0.8) screw.
Magnesium alloys have been in the focus of research in recent years as degradable biomaterial. The purpose of this study was the biomechanical characterisation of MgCa0.8-screws. The maximum pull out force of screws was determined in a synthetic bone without corrosion and after fixed intervals of corrosion: 24, 48, 72 and 96 h. This in vitro study has been carried out with Hank's solution with a flow rate corresponding to the blood flow in natural bone. A maximum pull out force (F(max)) of 201.5 ± 9.3 N was measured without corrosion. The biomechanical parameter decreased by 30% after 96 h in corrosive medium compared to the non-corrosion group. A maximum load capacity of 28 ± 7.6 N/h was determined. Our biomechanical data suggests that this biodegradable screw provides a promising bone-screw-fixation and has great potential for medical application.
Department of Orthopaedic Surgery, Hanover Medical School, Hanover, Germany. hazibullah.waizy@ddh-gruppe.de
Hazibullah
H
Waizy
Andreas
A
Weizbauer
Matthias
M
Maibaum
Frank
F
Witte
Henning
H
Windhagen
Arne
A
Lucas
Berend
B
Denkena
Andrea
A
Meyer-Lindenberg
Fritz
F
Thorey
D001696:Biomechanical Phenomena; D001863:Bone Screws; D002118:Calcium / Q000737:chemistry*; D004563:Electrochemistry; D066298:In Vitro Techniques; D008274:Magnesium / Q000737:chemistry*; D012039:Regional Blood Flow
D008274:Magnesium; D002118:Calcium