Acquired angioedema with C1 inhibitor deficiency associated with anticardiolipin antibodies.
Acquired angioedema (AAE) with C1 inhibitor deficiency is often associated to B cell lymphoproliferative disorders or autoimmune diseases. We report a case of AAE associated with IgM anti-cardiolipin antibodies, with frequent edematous attacks, that disappeared completely after a slight immunosuppression and danazol therapy.
E
E
Di Leo
E
E
Nettis
V
V
Montinaro
G
G
Calogiuri
P
P
Delle Donne
A
A
Ferrannini
A
A
Vacca
D000368:Aged; D000799:Angioedema / Q000175:diagnosis / Q000188:drug therapy / Q000276:immunology*; D017153:Antibodies, Anticardiolipin / Q000097:blood*; D001379:Azathioprine / Q000627:therapeutic use; D003174:Complement C1 Inactivator Proteins / Q000172:deficiency*; D050718:Complement C1 Inhibitor Protein; D003613:Danazol / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007075:Immunoglobulin M / Q000097:blood*; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D013988:Ticlopidine / Q000627:therapeutic use; D016896:Treatment Outcome
D017153:Antibodies, Anticardiolipin; D003174:Complement C1 Inactivator Proteins; D050718:Complement C1 Inhibitor Protein; D007075:Immunoglobulin M; D007166:Immunosuppressive Agents; C469952:SERPING1 protein, human; D001379:Azathioprine; D003613:Danazol; D013988:Ticlopidine