Familial aggregation of panic disturbances in Parkinson's disease.
Panic disorder has an elevated prevalence in Parkinson's disease (PD). To explore the basis for this co-occurrence, the familial aggregation of panic disorder was examined in patients with PD. Probands and relatives of patients with PD and panic disorder (PD-PANIC; N=20, N=115) and control probands with PD and no active psychiatric illness (PD-NA; N=17, N=108) were interviewed by phone, using a structured interview to determine panic status. Lifetime prevalence of panic and "panic-like" disorders was higher in PD-PANIC than in PD-NA relatives. Panic and "panic-like" disorders are familial disorders in PD.
Department of Psychiatry and Behavioral Sciences, Bloomberg School of Public Health, Baltimore, MD, USA. gponton1@jhmi.edu
Gregory M
GM
Pontone
Justin
J
Palanci
O Joseph
OJ
Bienvenu
Kung-Yee
KY
Liang
Gerald
G
Nestadt
Peter V
PV
Rabins
James R
JR
Williams
Laura
L
Marsh
D000368:Aged; D000369:Aged, 80 and over; D005192:Family Health; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D016584:Panic Disorder / Q000453:epidemiology* / Q000235:genetics*; D010300:Parkinson Disease / Q000453:epidemiology* / Q000235:genetics*; D011569:Psychiatric Status Rating Scales