Surgical treatment and radiation therapy of frontal lobe meningiomas in 7 dogs.
The cases of 7 adult dogs with generalized seizures managed by surgical excision and radiation therapy for frontal lobe meningiomas were reviewed. The neurological examination was unremarkable in 6 of the 7 dogs. Five dogs were operated on using a bilateral transfrontal sinus approach and 2 using a unilateral sinotemporal approach to the frontal lobe. One dog was euthanized 14 d after surgery; radiation therapy was initiated 3 wk after surgery in the remaining 6 dogs. Long-term follow-up consisted of neurological examination and magnetic resonance imaging (MRI) and/or computed tomography (CT) scan after radiation therapy. The mean survival time for dogs that had surgery and radiation therapy was 18 mo after surgery. Frontal lobe meningiomas have been associated with poor prognosis. However, the surgical approaches used in these cases, combined with radiation therapy, allow a survival rate for frontal lobe meningiomas similar to that for meningiomas located over the cerebral convexities.
Unité medico-chirurgicale de neurologie, Ecole Nationale Vétérinaire d'Alfort, Centre de Cancérologie Vétérinaire (Devauchel) - 7 Avenue du Générale du Gaulle-94700-Maisons-Alfort, France. auriarte@ndsr.co.uk
Ane
A
Uriarte
Pierre
P
Moissonnier
Jean-Laurent
JL
Thibaud
Edouard
E
Reyes-Gomez
Patrick
P
Devauchelle
Stéphane
S
Blot
D000818:Animals; D004283:Dog Diseases / Q000532:radiotherapy* / Q000601:surgery*; D004285:Dogs; D005260:Female; D005625:Frontal Lobe / Q000528:radiation effects / Q000601:surgery; D008297:Male; D008577:Meningeal Neoplasms / Q000532:radiotherapy / Q000601:surgery / Q000662:veterinary*; D008579:Meningioma / Q000532:radiotherapy / Q000601:surgery / Q000662:veterinary*; D011183:Postoperative Complications / Q000662:veterinary; D011379:Prognosis; D012640:Seizures / Q000209:etiology / Q000532:radiotherapy / Q000601:surgery / Q000662:veterinary; D016019:Survival Analysis; D016896:Treatment Outcome