[Novel oral anticancer drugs: a review of adverse drug reactions, interactions and patient adherence].
Each aspect of oncological care is widely affected by the spread of oral anticancer agents, which raises several questions in terms of safe medication use and patient adherence. Over the past decade targeted therapies have appeared in clinical practice and revolutionized the pharmacological treatment of malignancies. Regular patient - doctor visits and proper patient education is crucial in order to comply with the therapy previously agreed upon with the oncologist, to increase patient adherence, to detect and to treat adverse effects in early stages. Since the information on the new medicines in Hungarian language is sparse it is the intention of the authors to give an overview of the basic knowledge, patient safety issues, adverse effects and interactions. Official drug information summaries and data on pharmacokinetics, interactions and adverse effects from the literature are reviewed as the basis for this overview.
Országos Onkológiai Intézet Intézeti Gyógyszertár Budapest Ráth György u. 7-9. 1122. alexandra.bartal@gmail.com
Alexandra
A
Bartal
Zoltán
Z
Mátrai
Attila
A
Szucs
Galina
G
Belinszkaja
Zoltán
Z
Langmár
András
A
Rosta
D000284:Administration, Oral; D000970:Antineoplastic Agents / Q000008:administration & dosage* / Q000009:adverse effects*; D001943:Breast Neoplasms / Q000188:drug therapy*; D004334:Drug Administration Schedule; D004347:Drug Interactions; D064420:Drug-Related Side Effects and Adverse Reactions / Q000175:diagnosis*; D005260:Female; D018565:Food-Drug Interactions; D006801:Humans; D006814:Hungary; D055118:Medication Adherence; D058990:Molecular Targeted Therapy
D000970:Antineoplastic Agents