Effects of hydrolysed Saccharomyces cerevisiae yeast and yeast cell wall components on live performance, intestinal histo-morphology and humoral immune response of broilers.
1. The effects of enzymatically hydrolysed whole Saccharomyces cerevisiae yeast (HY) and the pellets of yeast cell wall (YCW) on production traits, the microbiology and histo-morphology of the small intestine, and humoral immune responses against Newcastle disease virus (NDV), of Ross 308 broilers were investigated.   2. The control group received a maize-soyabean meal based basal diet for 42 days. In the treated groups the basal diet was supplemented with 1 g/kg of HY and YCW. There were 8 replicate pens per group (n = 12 birds/pen).   3. HY and YCW supplementation improved live weight (P = 0·006) and FCR (P = 0·003) at 42-d as compared with the control group.   4. In the small intestine, Salmonella spp and Escherichia coli numbers were higher (P = 0·01) in the mucosa and lower (P = 0·01) in the digesta of the HY and the YCW fed groups at 25 d of age. Lactobacillus in the duodenal and jejunal digesta was higher (P < 0·05) in the HY and the YCW fed groups as compared with the control.   5. Following oral challenge with Salmonella pullorum, Escherichia coli and Lactobacillus increased (P < 0·05) in the mucosa and decreased in the digesta (P < 0·05) of the HY and YCW supplemented groups, relative to the control.   6. Supplementation of HY and YCW increased villus height in the jejunum (P = 0·02), width of villus in the ileum (P = 0·034) and number of goblet cells in villi of the jejunum (P = 0·006) and ileum (P = 0·01).   7. YCW increased antibody level against NDV at 21 and 42 d of age compared with the control and the HY supplemented diets (P < 0·05).   8. It was concluded that HY and YCW improved growth and feed efficiency in broilers, and considering the improvements in production traits and humoral immune responses, yeast cell wall may be a better dietary tool than the hydrolysed whole yeast cell as a performance enhancer for broilers.
Department of Animal Nutrition , West Bengal University of Animal & Fishery Sciences, Kolkata 700037, India.
N
N
Muthusamy
S
S
Haldar
T K
TK
Ghosh
M R
MR
Bedford
D000818:Animals; D000914:Antibodies, Viral / Q000097:blood; D001835:Body Weight / Q000276:immunology; D002473:Cell Wall / Q000276:immunology*; D002645:Chickens / Q000276:immunology* / Q000382:microbiology*; D015169:Colony Count, Microbial / Q000662:veterinary; D004435:Eating / Q000276:immunology; D006651:Histocytochemistry / Q000662:veterinary; D056724:Immunity, Humoral / Q000276:immunology; D007413:Intestinal Mucosa / Q000276:immunology / Q000382:microbiology; D007421:Intestine, Small / Q000166:cytology / Q000276:immunology* / Q000382:microbiology* / Q000648:ultrastructure; D012441:Saccharomyces cerevisiae / Q000276:immunology*
D000914:Antibodies, Viral