Bilateral methicillin-resistant Staphylococcus aureus keratitis following hyperopic photorefractive surgery.
To report clinical manifestations of a female patient with bilateral bacterial keratitis following photorefractive keratectomy (PRK). Bilateral PRK was performed for moderate hyperopia. Bandage contact lenses were fitted at the conclusion of the surgery. Bilateral infectious keratitis with hypopion was diagnosed within 4 days after surgery. Smear and culture were obtained and showed the presence of methicillin-resistant Staphylococcus aureus (MRSA). The patient was treated with systemic prednisone and topical antibiotics (vancomycin, tobramycin and netylmicin) and betamethasone. After 1 month corneal leukoma was still present and remained unchanged during the following 7 months. Infectious keratitis is a rare complication of PRK that appears early in the postoperative period. MRSA keratitis may determine long-term visual impairment despite prompt therapeutic intervention.
Dipartimento di Scienze Oftalmologiche, Università Federico II, Via Pansini 5, 80131 Naples, Italy.
Adriano
A
Magli
Raimondo
R
Forte
Luca
L
Rombetto
Roberta
R
Carelli
D000890:Anti-Infective Agents / Q000008:administration & dosage; D000995:Antitubercular Agents; D001372:Aza Compounds / Q000008:administration & dosage*; D003937:Diagnosis, Differential; D004305:Dose-Response Relationship, Drug; D005260:Female; D024841:Fluoroquinolones; D005500:Follow-Up Studies; D006801:Humans; D006956:Hyperopia / Q000601:surgery*; D007634:Keratitis / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D055624:Methicillin-Resistant Staphylococcus aureus / Q000302:isolation & purification*; D008875:Middle Aged; D000077266:Moxifloxacin; D009428:Netilmicin / Q000008:administration & dosage*; D009883:Ophthalmic Solutions; D018903:Photorefractive Keratectomy / Q000009:adverse effects*; D011804:Quinolines / Q000008:administration & dosage*; D013203:Staphylococcal Infections / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D014792:Visual Acuity
D000890:Anti-Infective Agents; D000995:Antitubercular Agents; D001372:Aza Compounds; D024841:Fluoroquinolones; D009883:Ophthalmic Solutions; D011804:Quinolines; D009428:Netilmicin; D000077266:Moxifloxacin