[Analysis on human papillomavirus 16 and 18 types infection among 805 patients with common anorectal lesions].
OBJECTIVE
To analyze the infection condition of human papillomavirus (HPV) type 16 and 18 in the squamous cells and columnar cells of patients with common anorecatal lesions.


METHODS
Infections of HPV type 16 and 18 were determined with real-time fluorescent quantitative PCR in the wax-embedded surgical specimen of 805 patients with common anorectal diseases.


RESULTS
The overall infection rate among 805 patients with anorecatal lesions was 66.1% (532/805). The infection rate was 82.6% (95/115) in patients with mixed hemorrhoids, 76.5% (88/115) in anal papillary fibromas, 74.8% (86/115) in internal hemorrhoids, 72.2% (83/115) in fistulas, 69.6% (80/115) in external hemorrhoids, 47.8% (55/115) in anal perianal abscesses, and 39.1% (45/115) in anal fissures.


CONCLUSIONS
Infection rate of HPV type 16, 18 in common anorectal lesions is high.
Department of Pathology, The Third Affiliated Hospital, Nanjing Traditional Chinese Medical University, Nanjing 210001, China. wxf_1982@163.com
Jian-xiang
JX
Geng
Zhi-ming
ZM
Fan
Yi-jiang
YJ
Ding
Jian-ning
JN
Chen
Su-min
SM
Zhang
Wei
W
Zhou
Shu-liang
SL
Huang
Dian-mei
DM
Han
D052162:Human papillomavirus 16; D052161:Human papillomavirus 18; D006801:Humans; D030361:Papillomavirus Infections; D012002:Rectal Diseases / Q000453:epidemiology*