[Prolonged complete response obtained by radiation and chemotherapy with paclitaxel in a case of recurrent gastric cancer in the rectovesical pouch].
The case is a 75-year-old man, who underwent curative resection for the upper part of stomach cancer (Stage II), and was without a recurrence for two years. The patient had been well until September 2006, when CT examination revealed a 5 cm tumor in the rectovesical pouch. The tumor was histologically diagnosed as a peritoneal metastasis of gastric cancer through CT-guided percutaneous needle biopsy. Chemotherapy with S-1 was initiated, but it resulted in progressive disease. To locally control the growing tumor and avoid rectal stenosis, irradiation was applied for a total of 56 Gy in December 2007 and then followed by chemotherapy with paclitaxel. He obtained a complete response 7-month later, and remains CR for 3 years by receiving paclitaxel chemotherapy. Although chemotherapy is of choice for gastric cancer recurrence, in some cases radiotherapy can play an important role in local control even in peritoneal metastasis.
Dept. of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences.
Nobuhiko
N
Kanaya
Shunsuke
S
Kagawa
Futoshi
F
Uno
Aya
A
Kunitomi
Nobuyuki
N
Ogawa
Toshiyoshi
T
Fujiwara
D000368:Aged; D000972:Antineoplastic Agents, Phytogenic / Q000627:therapeutic use*; D059248:Chemoradiotherapy; D006801:Humans; D008297:Male; D009367:Neoplasm Staging; D017239:Paclitaxel / Q000627:therapeutic use*; D012008:Recurrence; D012074:Remission Induction; D012186:Retroperitoneal Neoplasms / Q000556:secondary / Q000628:therapy*; D013274:Stomach Neoplasms / Q000473:pathology / Q000628:therapy*; D013997:Time Factors; D014057:Tomography, X-Ray Computed
D000972:Antineoplastic Agents, Phytogenic; D017239:Paclitaxel