Deep granulomatous dermatitis of the fin caused by Fusarium solani in a false killer whale (Pseudorca crassidens).
A 10-year-old female false killer whale (Pseudorca crassidens) developed skin lesions in the left breast fin. Histopathologically, the lesions consisted of multiple granulomas spread diffusely into the deep dermis and bone; characteristically, each granuloma had septate, branching fungal hyphae and chlamydospores surrounded by eosinophilic Splendore-Hoeppli materials. Macrophages, epithelioid cells and multinucleated giant cells in the granulomas reacted mainly to anti-SRA-E5 antibody against human macrophage scavenger receptor type I. Fusarium solani was isolated and its gene was detected from the skin samples. Mycotic skin lesions by Fusarium spp. reported so far in marine mammals were regarded as superficial dermatitis; therefore, the present case is very uncommon in that the lesions spread deeper into the skin.
Veterinary Pathology, Graduate School of Life and Environmental Science, Osaka Prefecture University, 1-58 Rinkuu ourai Kita, Izumisano, Osaka 598-8531, Japan.
Miyuu
M
Tanaka
Takeshi
T
Izawa
Mitsuru
M
Kuwamura
Tatsuko
T
Nakao
Yuko
Y
Maezono
Shu
S
Ito
Michiko
M
Murata
Masaru
M
Murakami
Ayako
A
Sano
Jyoji
J
Yamate
D058500:Animal Fins / Q000382:microbiology / Q000473:pathology*; D000818:Animals; D003872:Dermatitis / Q000473:pathology / Q000662:veterinary*; D004289:Dolphins / Q000382:microbiology*; D005260:Female; D060585:Fusariosis / Q000473:pathology / Q000662:veterinary*; D005670:Fusarium / Q000235:genetics*; D006099:Granuloma / Q000473:pathology / Q000662:veterinary*; D006652:Histological Techniques / Q000662:veterinary; D007150:Immunohistochemistry / Q000662:veterinary; D051117:Scavenger Receptors, Class A / Q000276:immunology
C495139:MSR1 protein, human; D051117:Scavenger Receptors, Class A