Development of broiler chickens after treatment with thymulin 5cH: a zoo technical approach.
Modulation of immune response due to thymulin 5cH has been previously observed. The aim of the present study is to evaluate the development of broiler chickens treated with thymulin 5cH by conventional zoo technical indices, phytohemaglutinin induced inflammation test and histomorphometric analysis of lymphoid organs (thymus, Fabricius bursa and spleen). Animals were divided in two groups: (a) test: birds with free access to thymulin 5cH diluted into the drink water and (b) control: birds with free access to water only, from the 1st to the 42nd day of life. All experimental procedures were done in blind. The results show that thymulin 5cH treated group had increased productivity index compared to control (391.45 versus 261.93) associated with higher viability in the 7th week (p = 0.013), and a possible shunt to B lymphocyte activity. The data suggest that thymulin 5cH could be a viable method to improve productivity in poultry production due to its immune modulation properties.
Centro de Pesquisa, Universidade Paulista, Rua Dr Bacelar, 1212. 4° andar, 04026-002 São Paulo, São Paulo, Brazil. satocesar@uol.com.br
César
C
Sato
Veranice Galha
VG
Listar
Leoni Villano
LV
Bonamin
D000284:Administration, Oral; D000822:Animal Husbandry; D000818:Animals; D001947:Breeding; D002060:Bursa of Fabricius / Q000187:drug effects; D002645:Chickens; D005260:Female; D006705:Homeopathy; D011201:Poultry Diseases / Q000517:prevention & control*; D013154:Spleen / Q000187:drug effects; D013935:Thymic Factor, Circulating / Q000008:administration & dosage / Q000494:pharmacology*; D013950:Thymus Gland / Q000187:drug effects; D016896:Treatment Outcome
D013935:Thymic Factor, Circulating