[Peritoneal lavage cytology under local anesthesia for detection of peritoneal recurrence after surgery].
Gastric cancer with positive peritoneal lavage cytology shows a very poor prognosis due to frequent peritoneal recurrence after surgery. Therefore, we have introduced neoadjuvant intra-peritoneal and systemic chemotherapy( NIPS) for gastric cancer with peritoneal microscopic and/or microscopic dissemination before surgery. In patients subjected to the strategy, we have experienced two cases of advanced gastric cancer with CY1, which had been treated with NIPS and curative surgery, had been performed with second peritoneal lavage cytology two years after surgery. In those two cases, S-1 was discontinued due to the negative results of peritoneal lavage cytology. We will present the cases.
Dept. of Gastroenterological Surgery, Graduate School of Medicine, Osaka University.
Kaoru
K
Okada
Yoshiyuki
Y
Fujiwara
Tsuyoshi
T
Takahashi
Yukinori
Y
Kurokawa
Makoto
M
Yamasaki
Hiroshi
H
Miyata
Kiyokazu
K
Nakajima
Shuji
S
Takiguchi
Masaki
M
Mori
Yuichiro
Y
Doki
D000368:Aged; D000772:Anesthesia, Local; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D000077143:Docetaxel; D004338:Drug Combinations; D006801:Humans; D008297:Male; D008875:Middle Aged; D020360:Neoadjuvant Therapy; D010094:Oxonic Acid / Q000008:administration & dosage / Q000627:therapeutic use; D010533:Peritoneal Lavage; D010534:Peritoneal Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000556:secondary / Q000628:therapy; D012008:Recurrence; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D043823:Taxoids / Q000008:administration & dosage / Q000627:therapeutic use; D005641:Tegafur / Q000008:administration & dosage / Q000627:therapeutic use; D014057:Tomography, X-Ray Computed
D004338:Drug Combinations; D043823:Taxoids; C079198:S 1 (combination); D005641:Tegafur; D000077143:Docetaxel; D010094:Oxonic Acid