[A case report of long-term survival of endocrine cell carcinoma of the esophagus with chemo-radiation therapy].
The patient was an 84-year-old man, who was diagnosed with cT3N2 (101L, 109L) M0, stage III esophageal cancer. The tumor, immunohistochemically, was stained positive for CD56 and NSE yielding a definitive diagnosis of endocrine cell carcinoma of the esophagus. We selected chemo-radiation therapy (5-FU/CDDP and 2 Gy/day total 60 Gy) for this patient. As adjuvant chemotherapy, 7 courses of chemotherapy with 5-FU/CDDP, was performed. At 8 months from the chemo-radiation therapy, the disease was diagnosed as cCR. But two years later, lung metastasis appeared, so we started chemotherapy with docetaxel/CDDP/5-FU. After 2 courses, lung metastasis was almost disappeared. He has been survived for four years and five months after chemo-radiation. This case suggests that chemo( FP) -radiation therapy and adjuvant chemotherapy could be an effective treatment for endocrine cell carcinoma of the esophagus.
Dept. of Surgery, Kinki Central Hospital.
Keiko
K
Tanizaki
Kenji
K
Kobayashi
Kou
K
Takachi
Kiyonori
K
Nishioka
Taro
T
Aoki
Satoshi
S
Hyuga
Yuko
Y
Igarashi
Chihiro
C
Yamanaka
Takamichi
T
Komori
Takashi
T
Matsumoto
Yoshio
Y
Uemura
D000369:Aged, 80 and over; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D059248:Chemoradiotherapy; D002945:Cisplatin / Q000008:administration & dosage / Q000627:therapeutic use; D004701:Endocrine Gland Neoplasms / Q000473:pathology / Q000628:therapy*; D004938:Esophageal Neoplasms / Q000473:pathology / Q000628:therapy*; D005472:Fluorouracil / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D008297:Male; D009367:Neoplasm Staging; D013997:Time Factors
D002945:Cisplatin; D005472:Fluorouracil