Recent progress in targeting cancer.
In recent years, numerous new targets have been identified and new experimental therapeutics have been developed. Importantly, existing non-cancer drugs found novel use in cancer therapy. And even more importantly, new original therapeutic strategies to increase potency, selectivity and decrease detrimental side effects have been evaluated. Here we review some recent advances in targeting cancer.
Department of Cell Stress Biology, Roswell Park Cancer Institute, Buffalo, NY 14263, USA. zoya.demidenko@roswellpark.org
Zoya N
ZN
Demidenko
James A
JA
McCubrey
D000970:Antineoplastic Agents / Q000494:pharmacology* / Q000627:therapeutic use*; D015972:Gene Expression Regulation, Neoplastic / Q000187:drug effects; D006801:Humans; D058990:Molecular Targeted Therapy; D009363:Neoplasm Proteins / Q000235:genetics / Q000378:metabolism; D009369:Neoplasms / Q000188:drug therapy* / Q000517:prevention & control*; D015398:Signal Transduction
D000970:Antineoplastic Agents; D009363:Neoplasm Proteins