Resolution of isomeric multi-ruthenated porphyrins by travelling wave ion mobility mass spectrometry.
The ability of travelling wave ion mobility mass spectrometry (TWIM-MS) to resolve cationic meta/para and cis/trans isomers of mono-, di-, tri- and tetra-ruthenated supramolecular porphyrins was investigated. All meta isomers were found to be more compact than the para isomers and therefore mixtures of all isomeric pairs could be properly resolved with baseline or close to baseline peak-to-peak resolution (R(p-p)). Di-substituted cis/trans isomers were found, however, to present very similar drift times and could not be resolved. N(2) and CO(2) were tested as the drift gas, and similar α but considerably better values of R(p) and R(p-p) were always observed for CO(2).
ThoMSon Mass Spectrometry Laboratory, Institute of Chemistry, University of Campinas, UNICAMP 13083-970, Campinas, SP, Brazil.
Priscila M
PM
Lalli
Bernardo A
BA
Iglesias
Daiana K
DK
Deda
Henrique E
HE
Toma
Gilberto F
GF
de Sa
Romeu J
RJ
Daroda
Koiti
K
Araki
Marcos N
MN
Eberlin
D002245:Carbon Dioxide; D007536:Isomerism; D013058:Mass Spectrometry / Q000379:methods*; D008958:Models, Molecular; D009584:Nitrogen; D011166:Porphyrins / Q000737:chemistry*; D012428:Ruthenium / Q000737:chemistry*
D011166:Porphyrins; D002245:Carbon Dioxide; D012428:Ruthenium; D009584:Nitrogen