[A case report of GIST of the small intestine with multiple liver abscesses].
We report a case of a woman in her fifties presenting with abdominal pain, headache and high fever. Blood examination showed a high CRP level and liver dysfunction, and then abdominal CT scan showed multiple liver masses and a 5 cm submucosal tumor of the small intestine. We diagnosed the multiple liver masses as liver abscesses, so we administered antibiotics. We suspected that the tumor was a cause of liver abscesses, and then performed a resection of the tumor and partial small intestine on the third day of hospitalization. We diagnosed the tumor as GIST because it was positive for c-kit and CD34 by immunohistochemistry. One of the resected liver nodules showed negative for c-kit and CD34, and we diagnosed it as a liver abscess. We performed percutaneous transhepatic abscess drainage (PTAD) because she ran into high fever after the operation, and then she recovered. We consider she has the possibility of liver metastasis, so we administered imatinib mesylate to her. No recurrence was found for 11 months after the operation. This case provides valuable information because there are few reports of GIST with liver abscesses.
Dept. of Internal Medicine, Minoh City Hospital.
Satoshi
S
Ogura
Mamoru
M
Yura
Takuya
T
Sakamoto
Yuka
Y
Watanabe
Naoko
N
Tani
Tsuyoshi
T
Yamakita
Masami
M
Yamazaki
Akihiro
A
Nishihara
Kenji
K
Takaishi
Yasuhiro
Y
Miyake
Hiroshi
H
Mori
Shinji
S
Tamura
D000970:Antineoplastic Agents / Q000627:therapeutic use; D001549:Benzamides; D003131:Combined Modality Therapy; D004322:Drainage; D005260:Female; D046152:Gastrointestinal Stromal Tumors / Q000150:complications / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007078:Ileal Neoplasms / Q000150:complications / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D000068877:Imatinib Mesylate; D008100:Liver Abscess / Q000209:etiology* / Q000628:therapy; D008875:Middle Aged; D010879:Piperazines / Q000627:therapeutic use; D011743:Pyrimidines / Q000627:therapeutic use; D014057:Tomography, X-Ray Computed
D000970:Antineoplastic Agents; D001549:Benzamides; D010879:Piperazines; D011743:Pyrimidines; D000068877:Imatinib Mesylate