Recent patents on oligonucleotide synthesis and gene synthesis.
Gene synthesis is an emerging field which has widespread implications in synthetic biology and molecular biology. The field is constantly evolving which has led to key advances in oligonucleotide synthesis and gene synthesis technologies, with simplicity, cost effectiveness and high throughput. The miniaturization, multiplexing, microfluidic processing and the integrated microchip engineering will drive down cost and increase productivity without compromising DNA synthesis fidelity, whereas the gigantic amount of genome information provides infinite source of DNA elements and genes as raw material for synthetic biology. This article describes some of the recent patents on oligonucleotide synthesis and gene synthesis.
The Key Laboratory of Gene Engineering of Ministry of Education and Biotechnology Research Center, The School of Life Sciences, Sun Yat-sen University, Guangzhou 510275, P. R. China. yts9009@sina.com
Tingsheng
T
Yu
Xiao
X
Bao
Wenxian
W
Piao
Jingli
J
Peng
Wei
W
Li
Cui
C
Yang
Meng
M
Xing
Yiliu
Y
Zhang
Jinhuan
J
Qi
Lei
L
Xu
Li
L
Xu
Qiuyun
Q
Liu
D005813:Genes, Synthetic / Q000235:genetics*; D046210:Microfluidic Analytical Techniques; D009841:Oligonucleotides / Q000138:chemical synthesis* / Q000737:chemistry; D009943:Organophosphorus Compounds / Q000737:chemistry; D010330:Patents as Topic; D016133:Polymerase Chain Reaction; D013455:Sulfur / Q000737:chemistry
D009841:Oligonucleotides; D009943:Organophosphorus Compounds; C434331:phosphoramidite; D013455:Sulfur