Liver abscess as the presenting manifestation of chronic granulomatous disease.
Chronic granulomatous disease (CGD) is a rare primary immunodeficiency disease, affecting phagocytic blood cells, which predispose patients to recurrent infectious complications. Herein, an 11-year-old girl is described who presented with liver abscess at the age of 9 years. Positive dihydrorhodamine (DHR) and nitrobluetetrazolium (NBT) tests confirmed the diagnosis of CGD for the patient. Anti-tuberculosis drugs and parenteral antibiotic therapy were started. Unusual visceral abscess and recurrent infections should be considered as an alarm for primary immunodeficiency diseases, while early diagnosis and appropriate treatment could prevent severe complications and even death in this group of patients.
Tehran University of Medical Sciences Infectious Disease Research Center Tehran Iran. smamishi@sina.tums.ac.ir
Setareh
S
Mamishi
Faezeh
F
Ahmadi
Maedeh
M
Ahmadi
Nima
N
Rezaei
D002648:Child; D005260:Female; D006105:Granulomatous Disease, Chronic / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D008100:Liver Abscess / Q000209:etiology*