Rhodium(II)-catalyzed asymmetric sulfur(VI) reduction of diazo sulfonylamidines.
Diazo sulfonylamidines readily undergo enantioselective oxygen transfer from sulfur to carbon atom in the presence of chiral rhodium(II) carboxylates resulting in chiral sulfinylamidines. This unusual asymmetric atom transfer "reduction" occurs rapidly under mild conditions, and sulfinylamidines are obtained in excellent yield.
The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA.
Nicklas
N
Selander
Valery V
VV
Fokin
D000578:Amidines / Q000737:chemistry*; D001391:Azo Compounds / Q000737:chemistry*; D002384:Catalysis; D018360:Crystallography, X-Ray; D008958:Models, Molecular; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D010084:Oxidation-Reduction; D012238:Rhodium / Q000737:chemistry*; D013237:Stereoisomerism; D013441:Sulfinic Acids / Q000737:chemistry*; D013455:Sulfur / Q000737:chemistry*
D000578:Amidines; D001391:Azo Compounds; D009942:Organometallic Compounds; D013441:Sulfinic Acids; D013455:Sulfur; D012238:Rhodium