Isolation of friedelin from black condensate of cork.
Black condensates (BC) are wastes of the insulation corkboard industry that contain several valuable chemicals, including friedelin, a terpene exhibiting biological activity. Herein, we report a straightforward procedure to extract friedelin from BC. Using this procedure, we were able to extract friedelin with yields between 0.4% and 2.9% and to further purify it obtaining purities from 77.0% to 99.3% (HPLC). The initial BC (2 batches), extracted raw product and purified friedelin were analyzed using FTIR. The extraction yields and purities were found to be directly related to the intensity of the carbonyl vibration at 1713 cm(-1) in the FTIR spectrum of the used BC batch. Therefore, these spectra can be used to screen and select BC batches suitable for friedelin extraction.
3B's Research Group - Biomaterials, Biodegradables and Biomimetics, University of Minho, AvePark, 4806-909 Taipas - Guimarães, Portugal. rpires@dep.uminho.pt
Ricardo A
RA
Pires
Ivo
I
Aroso
Susana P
SP
Silva
João F
JF
Mano
Rui L
RL
Reis
D003252:Construction Materials / Q000032:analysis*; D007220:Industrial Waste / Q000032:analysis*; D014315:Triterpenes / Q000302:isolation & purification*; D000094042:Lupanes
D007220:Industrial Waste; D014315:Triterpenes; C060796:friedelin; D000094042:Lupanes