An H(∞) approach for elasticity properties reconstruction.
OBJECTIVE
Quantification of object elasticity properties has significant technical implications as well as important practical applications, such as medical disease diagnosis. In general, given noisy measurements on the kinematic states of the objects from imaging data, the aim is to recover the elasticity parameters for assumed material constitutive models of the objects. The implementation is complicated caused by the large dimensionality of the parameters.


METHODS
Various versions of the least-square (LS) methods have been widely used, which, however, do not perform well under reasonably realistic levels of disturbances. Another popular strategy, based on the extended Kalman filter (EKF), is also far from optimal and subject to divergence if either the initializations are poor or the noises are not Gaussian. In this paper, the authors propose a robust system identification paradigm for the quantitative analysis of object elasticity. It is derived and extended from the H(∞) filtering principles and is particularly powerful for real-world situations where the types and levels of the disturbances are unknown.


RESULTS
Using synthetic data, the authors investigate the sensitivity of the strategies toward different types (Gaussian and Poisson) and levels of noises, as well as various initializations. The experimental results show consistently superior performance of the proposed method over the LS and EKF algorithms in reliably identifying object elastic modulus distributions.


CONCLUSIONS
Results from phase contrast imaging data of canine hearts and human MRI data are also presented, which demonstrate the power of the framework.
State Key Laboratory of Modern Optical Instrumentation, Zhejiang University, Hangzhou 310027, China. huafeng.liu@rit.edu
Huafeng
H
Liu
Hongjie
H
Hu
Albert J
AJ
Sinusas
Pengcheng
P
Shi
D000465:Algorithms; D003198:Computer Simulation; D055119:Elastic Modulus / Q000502:physiology; D054459:Elasticity Imaging Techniques / Q000379:methods*; D006321:Heart / Q000502:physiology*; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D008955:Models, Cardiovascular; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity