Isolation and characterization of self-fertile suppressors from the sterile nsdD deletion mutant of Aspergillus nidulans.
To identify downstream and/or interactive factors of the nsdD gene, which encodes a positive regulator of sexual development of Aspergillus nidulans, suppressor mutants displaying a self-fertile phenotype were isolated from a sterile nsdD deletion mutant. At least five different loci (sndA-E) were identified and genetically analyzed. In the nsdD                         (+) background, most of the suppressors showed a marked increment of sexual development, even under the stress conditions that normally inhibited sexual development. The common phenotype of the suppressor mutants suggested the involvement of the snd genes in the negative regulation of sexual development in response to the environmental factors.
Division of Life Science, Wonkwang University, Iksan 570-749, Republic of Korea.
Dong-Beom
DB
Lee
Lee Han
LH
Kim
Jin-Pyo
JP
Kim
Kap-Hoon
KH
Han
Dong-Min
DM
Han
D001233:Aspergillus nidulans / Q000235:genetics* / Q000254:growth & development / Q000502:physiology*; D005656:Fungal Proteins / Q000235:genetics* / Q000378:metabolism; D017353:Gene Deletion; D018507:Gene Expression Regulation, Developmental; D012098:Reproduction; D012100:Reproduction, Asexual; D013489:Suppression, Genetic
D005656:Fungal Proteins