[Validation of a simplified prediction rule to identify etiology in children with pneumonia].
Identifying on admission those children with bacterial pneumonia could reduce inappropriate antibiotic use. The BPS (Bacterial Pneumonia Score) is a clinical prediction rule that accurately identifies children with bacterial pneumonia. Because the interpretation of chest X-ray included in this model could be considered difficult, a simplified version was developed, but this version has not yet been validated in a different population.



To validate a simplified clinical prediction rule to identify children with an increased risk of having bacterial pneumonia.



Children aged under 5 years, hospitalized for pneumonia (viral or bacterial) were included. On admission, axillary temperature, age, absolute neutrophil count, bands, and chest radiograph were evaluated.



We included 168 patients (23 with bacterial pneumonia and 145 with viral pneumonia). Those with bacterial pneumonia showed a score higher than those with viral pneumonia (5.3 ± 2.5 vs. 2.6 ± 2.02; p <0.001). A score =3 points was identified as the optimum cutoff value to predict bacterial pneumonia (aucROC= 0.79; 95% IC: 0.68-0.90), and was more frequent among patients with bacterial than viral pneumonia (19/23 vs. 42/145, p= 0.003; OR: 4.8; CI95%: 1.4-17.6), achieving 82.6% sensitivity, 50.3% specificity, 20.9% positive predictive value, 94.8% negative predictive value, 1.66 positive likelihood ratio and 0.35 negative likelihood ratio.



The evaluated simplified prediction rule showed a limited diagnostic accuracy on identifying children with bacterial pneumonia, being less accurate than the BPS.
División Neumotisiología, Hospital General de Niños Pedro de Elizalde. mariela_lopez11@hotmail.com
Mariela
M
López
Fernando
F
Torres
Carolina
C
Davenport
María José
MJ
Rial
Norma
N
González
Fernando
F
Ferrero
D002675:Child, Preschool; D003430:Cross-Sectional Studies; D003937:Diagnosis, Differential; D006801:Humans; D007223:Infant; D018410:Pneumonia, Bacterial / Q000175:diagnosis*; D011024:Pneumonia, Viral / Q000175:diagnosis*; D011237:Predictive Value of Tests; D012307:Risk Factors