Observation of backbone self-crossings of organismal DNAs through atomic force microscopy.
It is demonstrated in our studies that intrinsic curvatures of organismal DNAs could lead to the generation of duplex backbone self-crossings in their relaxed forms. In addition, the backbone self-crossings of the organismal DNAs could be readily confirmed through atomic force microscopic examination.
Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore.
Dawei
D
Li
Zhaoqi
Z
Yang
Bei
B
Lv
Tianhu
T
Li
D004247:DNA / Q000737:chemistry*; D018625:Microscopy, Atomic Force
D004247:DNA