Thiamine in nutrition therapy.
Clinicians involved with nutrition therapy traditionally concentrated on macronutrients and have generally neglected the importance of micronutrients, both vitamins and trace elements. Micronutrients, which work in unison, are important for fundamental biological processes and enzymatic reactions, and deficiencies may lead to disastrous consequences. This review concentrates on vitamin B(1), or thiamine. Alcoholism is not the only risk factor for thiamine deficiency, and thiamine deficiency is often not suspected in seemingly well-nourished or even overnourished patients. Deficiency of thiamine has historically been described as beriberi but may often be seen in current-day practice, manifesting as neurologic abnormalities, mental changes, congestive heart failure, unexplained metabolic acidosis, and so on. This review explains the importance of thiamine in nutrition therapy and offers practical tips on prevention and management of deficiency states.
Department of Surgery, Room 3350, Stroger Hospital, 1901 West Harrison St, Chicago, IL 60612, USA. ksriram@cookcountyhhs.org
Krishnan
K
Sriram
William
W
Manzanares
Kimberly
K
Joseph
D000437:Alcoholism / Q000150:complications; D006801:Humans; D044623:Nutrition Therapy; D009752:Nutritional Status; D013831:Thiamine / Q000097:blood / Q000627:therapeutic use*; D013832:Thiamine Deficiency / Q000150:complications / Q000178:diet therapy / Q000517:prevention & control*; D014803:Vitamin B Complex / Q000097:blood / Q000627:therapeutic use*
D014803:Vitamin B Complex; D013831:Thiamine