Atypical teratoid rhabdoid tumor located in the pineal region following prophylactic irradiation for acute lymphoblastic leukemia.
Atypical teratoid rhabdoid tumor (AT/RT) is a rare entity. In the central nervous system, AT/RT generally arises from the posterior fossa of infants and behaves aggressively. AT/RT is reported to arise from the infratentorial region (63%) and other sites, such as the suprasellar region, cerebellopontine angle, and spinal cord. The pineal region is rare (6%) as a site of origin. Radiation-induced brain tumors are well known. In this report, we present a case of a pineal region tumor causing acute hydrocephalus that could be pathologically diagnosed as AT/RT following prophylactic cranial irradiation for acute lymphoblastic leukemia.
Department of Neurosurgery, Yamagata University Faculty of Medicine, Japan. akuge@med.id.yamagata-u.ac.jp
Atsushi
A
Kuge
Shinya
S
Sato
Kaori
K
Sakurada
Sunao
S
Takemura
Takamasa
T
Kayama
D002675:Child, Preschool; D016371:Cranial Irradiation / Q000009:adverse effects; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D009381:Neoplasms, Radiation-Induced / Q000473:pathology* / Q000601:surgery; D010871:Pinealoma / Q000209:etiology / Q000473:pathology* / Q000601:surgery; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000532:radiotherapy; D018335:Rhabdoid Tumor / Q000209:etiology / Q000473:pathology* / Q000601:surgery; D013724:Teratoma / Q000209:etiology / Q000473:pathology* / Q000601:surgery; D055815:Young Adult