Advances in pump technology: insulin patch pumps, combined pumps and glucose sensors, and implanted pumps.
This review discusses the most recent developments in insulin pump technology. The benefits of the insulin pump to patients with type 1 diabetes are recognized both for its metabolic effectiveness and its positive effects on quality of life. The current pumps are reliable, small and light, and are becoming more and more sophisticated. Nevertheless, there remain practical and psychological constraints for the patient. However, recent patch-pump advances should simplify the technical aspects of pump treatment and enhance patient comfort. Another advance combines the insulin pump with a glucose sensor. Such a combination is logical for optimizing pump use and, to that end, developing an automated or 'closed-loop'system that permits the delivery of subcutaneous insulin adjusted according to measured levels of subcutaneous glucose. Finally, implanted insulin pumps have proven their worth not only because of their simple use, but also for their contribution in the artificial pancreas project. Indeed, the prompt response with intraperitoneal administration of insulin makes it of interest for use in a closed-loop system.
Service d'endocrinologie, nutrition et maladies métaboliques, CHU-Hôpitaux sud, 270, Boulevard de Sainte Marguerite, 13009 Marseille, France. pauline.schaepelynck@ap-hm.fr
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Schaepelynck
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Darmon
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Molines
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Jannot-Lamotte
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Treglia
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Raccah
D000704:Analysis of Variance; D001786:Blood Glucose / Q000187:drug effects / Q000378:metabolism*; D003922:Diabetes Mellitus, Type 1 / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007004:Hypoglycemic Agents / Q000008:administration & dosage*; D015918:Infusion Pumps, Implantable / Q000639:trends*; D007332:Insulin Infusion Systems / Q000639:trends*; D008297:Male; D011788:Quality of Life
D001786:Blood Glucose; D007004:Hypoglycemic Agents