Escherichia coli producing CMY-2 β-lactamase in bovine mastitis milk.
An Escherichia coli isolate producing the CMY-2 β-lactamase was found in the milk of a cow with recurrent subclinical mastitis. The isolate was resistant to the antibiotics commonly used for intramammary mastitis treatment, such as penicillins, cephalosporins, β-lactam/β-lactamase  inhibitor combinations, aminoglycosides, tetracyclines, and sulfonamides. This is the first report of a plasmid-mediated AmpC-producing Enterobacteriaceae in bovine milk.
Institute of Veterinary Bacteriology, University of Bern, Bern, Switzerland.
Andrea
A
Endimiani
Isabelle
I
Bertschy
Vincent
V
Perreten
D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001426:Bacterial Proteins; D002417:Cattle; D004926:Escherichia coli / Q000187:drug effects* / Q000201:enzymology*; D005260:Female; D006801:Humans; D008414:Mastitis, Bovine / Q000382:microbiology; D008826:Microbial Sensitivity Tests; D008892:Milk / Q000201:enzymology / Q000382:microbiology*; D015995:Prevalence; D018440:beta-Lactam Resistance; D001618:beta-Lactamases / Q000096:biosynthesis*
D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; C103022:beta-lactamase CMY-2; C048795:AmpC beta-lactamases; D001618:beta-Lactamases