Evaluation of xTAG Respiratory Viral Panel FAST and xTAG Human Parainfluenza Virus Analyte-Specific Reagents for detection of human parainfluenza viruses in respiratory specimens.
The multiplex xTAG(®) Respiratory Viral Panel FAST (RVP FAST) research-use-only assay and xTAG(®) Human Parainfluenza Virus Analyte-Specific Reagent (HPIV-ASR) assay were evaluated with 99 culture-confirmed human parainfluenza virus (HPIV)-positive and -negative specimens and found to have analytical sensitivities of 95.2% and 100% and specificities of 98.3% and 96.6%, respectively. Since the in vitro diagnostic (IVD) version of the RVP FAST assay does not include HPIVs, the HPIV-ASR assay can be tested in parallel with RVP FAST-IVD for optimal detection of HPIVs.
Department of Pathology and Laboratory Medicine, Children's Mercy Hospitals and Clinics, Kansas City, MO 64108, USA.
Suresh B
SB
Selvaraju
Rangaraj
R
Selvarangan
D006801:Humans; D010252:Paramyxoviridae / Q000235:genetics / Q000302:isolation & purification*; D018184:Paramyxoviridae Infections / Q000175:diagnosis*; D011933:Reagent Kits, Diagnostic; D015203:Reproducibility of Results; D012137:Respiratory System / Q000821:virology; D012680:Sensitivity and Specificity
D011933:Reagent Kits, Diagnostic