Antigen-responsive, microfluidic valves for single use diagnostics.
The growing need for medical diagnostics in resource limited settings is driving the development of simple, standalone immunoassay devices. A capillary flow device using polymerization based amplification is capable of blocking a microfluidic channel in response to target biomaterials, enabling multiple modes of detection that require little or no supplemental instrumentation.
Chemical and Biological Engineering, UCB 424, University of Colorado, Boulder, CO 80309, USA.
Brad J
BJ
Berron
Allison M
AM
May
Zheng
Z
Zheng
Vivek
V
Balasubramaniam
Christopher N
CN
Bowman
D000941:Antigens / Q000737:chemistry* / Q000276:immunology / Q000378:metabolism; D006801:Humans; D007118:Immunoassay / Q000295:instrumentation / Q000379:methods; D046210:Microfluidic Analytical Techniques / Q000295:instrumentation* / Q000379:methods*
D000941:Antigens