Uterine adenosarcoma with ovarian sex cord-like differentiation: a case report and review of the literature.
OBJECTIVE
To determine the prognosis of uterine adenosarcoma with ovarian sex cord like-differentiation after treatment and to review the literature.


METHODS
A 47-year-old premenopausal unmarried woman presented with irregular menstrual bleeding and uterine mass. Sonographic examination, suggested two uterine fibroids located in the uterine fundus and cervix measuring 4 × 3 cm and 3 × 3 cm, respectively. Total abdominal hysterectomy with bilateral salpingo-oopherectomy was performed and the histopathology report confirmed the diagnosis of uterine adenosarcoma with ovarian sex cord like-differentiation. The patient received neither chemotherapy nor other adjuvant therapy because the tumor had low malignant potential, and the extent of myometrial invasion was less than half of the whole myometrium. The patient had an uneventful recovery, and no recurrence was detected for 2 years in the follow-up period.


CONCLUSIONS
Uterine adenosarcomas mostly have relatively low malignant potential. Surgery is the optimal standard treatment for patients. Although there is not enough data in the present literature, benign epithelial differentiations, such as sex cord-like elements may reflect the behaviour of the tumour and shows the tendency to have a benign course in most of cases.
Department of Obstetrics and Gynecology, Bakirkoy Women and Children Training and Research Hospital, Istanbul, Turkey.
Volkan
V
Ulker
Ekrem
E
Yavuz
Ali
A
Gedikbasi
Ceyhun
C
Numanoglu
Sinem
S
Sudolmus
Ahmet
A
Gulkilik
D018195:Adenosarcoma / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D007044:Hysterectomy; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000473:pathology* / Q000601:surgery; D010052:Ovariectomy; D011379:Prognosis; D058994:Salpingectomy; D018312:Sex Cord-Gonadal Stromal Tumors / Q000473:pathology* / Q000601:surgery; D014594:Uterine Neoplasms / Q000473:pathology* / Q000601:surgery