Convenient nomenclature of cysteine-rich polypeptide toxins from sea anemones.
Polypeptide toxins are the main constituents of natural venoms. Considerable progress in the study of these molecules has resulted in the determination of a large number of structurally related sequences. To classify newly discovered molecules, a rational nomenclature for naming peptide toxins was developed, which takes into account toxin biological activity, the species name, and structural peculiarities of the polypeptide. Herein, we suggest modifications to this nomenclature for cysteine-rich polypeptide toxins from sea anemones and describe 11 novel polypeptide structures deduced after common database revision.
Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, ul Miklukho-Maklaya 16/10, 117997 Moscow, Russia. serg@ibch.ru
Sergey
S
Kozlov
Eugene
E
Grishin
D020816:Amino Acid Motifs; D000595:Amino Acid Sequence; D000818:Animals; D003064:Cnidarian Venoms / Q000737:chemistry* / Q000145:classification; D003545:Cysteine / Q000737:chemistry*; D030562:Databases, Protein; D008969:Molecular Sequence Data; D012615:Sea Anemones; D020539:Sequence Analysis, Protein; D009626:Terminology as Topic
D003064:Cnidarian Venoms; D003545:Cysteine