A new diacylated labdane diterpenoid from Andrographis wightiana.
A new acylated labdane diterpenoid, 14-deoxy-3,19-diacetyl-11,12-didehydroandrographolide (1), together with three known labdane diterpenoids, wightionolide (2), andrographolide (3) and neoandrographolide (4), and three known flavones, echioidinin (5), skullcapflavone I 2'-methyl ether (6) and echioidin (7), were isolated from the whole plant of Andrographis wightiana. The structure of compound 1 was elucidated by 1D and extensive 2D-NMR spectral studies.
Natural Products Division, Department of Chemistry, Sri Venkateswara University, Tirupati 517 502, India.
Jalli Madhu
JM
Sudhana
Rachakunta
R
Munikishore
Mopuru Vijayabhaskar
MV
Reddy
Duvvuru
D
Gunasekar
Alain
A
Blond
Bernard
B
Bodo
D035685:Andrographis / Q000737:chemistry*; D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification*; D047309:Flavones / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure
D004224:Diterpenes; D047309:Flavones; C569880:deoxy-3,19-diacetyl-11,12-didehydroandrographolide