Effect of protein adsorption on the fluorescence of ultrasmall gold nanoclusters.
The interaction of proteins with ultrasmall gold nanoclusters (Au NCs) is investigated. Upon protein association, the fluorescence of Au NCs is significantly enhanced and, concomitantly, their luminescence lifetime is prolonged. The results stress the importance of investigating the behavior of fluorescent metal NCs in complex biological environment for advancing their bio-nanotechnology applications.
Institute of Applied Physics and Center for Functional Nanostructures (CFN), Karlsruhe Institute of Technology (KIT), Karlsruhe, Germany.
Li
L
Shang
Stefan
S
Brandholt
Florian
F
Stockmar
Vanessa
V
Trouillet
Michael
M
Bruns
G Ulrich
GU
Nienhaus
D000327:Adsorption; D005453:Fluorescence; D006046:Gold / Q000737:chemistry*; D053768:Metal Nanoparticles / Q000737:chemistry*; D036103:Nanotechnology / Q000379:methods*; D011506:Proteins / Q000737:chemistry*
D011506:Proteins; D006046:Gold