title: Rotary blood pump control using integrated inlet pressure sensor.
abstract: Due to improved reliability and reduced risk of thromboembolic events, continuous flow left ventricular assist devices are being used more commonly as a long term treatment for end-stage heart failure. As more and more patients with these devices are leaving the hospital, a reliable control system is needed that can adjust pump support in response to changes in physiologic demand. An inlet pressure sensor has been developed that can be integrated with existing assist devices. A control system has been designed to adjust pump speed based on peak-to-peak changes in inlet pressure. The inlet pressure sensor and control system have been tested with the HeartMate II axial flow blood pump using a mock circulatory loop and an active left ventricle model. The closed loop control system increased total systemic flow and reduced ventricular load following a change in preload as compared to fixed speed control. The increase in systemic flow occurred under all operating conditions, and maximum unloading occurred in the case of reduced ventricular contractility.
authors.affiliation: Division of Artificial Organs, Department of Surgery, Penn State College of Medicine, Hershey, Pennsylvania, USA. jpc121@psu.edu
authors.forename: Joshua
authors.initials: J
authors.lastname: Cysyk
authors.forename: Choon-Sik
authors.initials: CS
authors.lastname: Jhun
authors.forename: Ray
authors.initials: R
authors.lastname: Newswanger
authors.forename: William
authors.initials: W
authors.lastname: Weiss
authors.forename: Gerson
authors.initials: G
authors.lastname: Rosenberg
mesh_terms: D003198:Computer Simulation; D004867:Equipment Design; D019544:Equipment Failure Analysis; D006352:Heart Ventricles / Q000503:physiopathology* / Q000601:surgery; D006353:Heart-Assist Devices; D006801:Humans; D007260:Infusion Pumps; D008955:Models, Cardiovascular; D018511:Systems Integration; D014160:Transducers, Pressure