title: [The effect of MAB225 on radiosensitivity of salivary gland adenoid cystic carcinoma].
abstract: OBJECTIVE
  To observe the effect of epidermal growth factor receptor's monoclonal antibody(MAB225) on radiosensitivity of salivary gland adenoid cystic carcinoma cell.
  
  
  METHODS
  Bi-fluorescence stain ,MTT test and fluorescence flow cytometry(FCM) were used to observe the apoptosis rate and radiosensitizing effect for MAB225 on ACC-2 cell.SPSS11.0 software package was used for data analysis.
  
  
  RESULTS
  Through bi-fluorescence stain, MTT test and fluorescence flow cytometry(FCM),it was found that MAB225 combined with radiation treatment produced a 3-fold induction of apoptosis rate, whereas exposure to radiation alone induced apoptosis only 1 fold, compared to the control group.
  
  
  CONCLUSIONS
  MAB225 enhanced radiosensitivity and decreased survival rates of ACC-2 cell in vitro after radiation.
authors.affiliation: Department of Oral and Maxillofacial Surgey, Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory of Stomatology. Shanghai 200011,China. cycstal2002@126.com
authors.forename: Liu
authors.initials: L
authors.lastname: Liu
authors.forename: Xiu-ming
authors.initials: XM
authors.lastname: Liu
authors.forename: Yan
authors.initials: Y
authors.lastname: Lv
authors.forename: Hai-sheng
authors.initials: HS
authors.lastname: Hu
authors.forename: Yi-li
authors.initials: YL
authors.lastname: Cai
mesh_terms: D017209:Apoptosis; D003528:Carcinoma, Adenoid Cystic; D002294:Carcinoma, Squamous Cell; D006258:Head and Neck Neoplasms; D006801:Humans; D011836:Radiation Tolerance; D012468:Salivary Gland Neoplasms; D012469:Salivary Glands; D000077195:Squamous Cell Carcinoma of Head and Neck