title: Functional genomics of allergen gene families in fruits.
abstract: Fruit consumption is encouraged for health reasons; however, fruits may harbour a series of allergenic proteins that may cause discomfort or even represent serious threats to certain individuals. Thus, the identification and characterization of allergens in fruits requires novel approaches involving genomic and proteomic tools. Since avoidance of fruits also negatively affects the quality of patients' lives, biotechnological interventions are ongoing to produce low allergenic fruits by down regulating specific genes. In this respect, the control of proteins associated with allergenicity could be achieved by fine tuning the spatial and temporal expression of the relevant genes.
authors.affiliation: Plant Biotechnology Unit, IAM, Department of Biotechnology, VIBT BOKU, 1190 Vienna, Austria. fatemeh.maghuly@boku.ac.at
authors.forename: Fatemeh
authors.initials: F
authors.lastname: Maghuly
authors.forename: Gorji
authors.initials: G
authors.lastname: Marzban
authors.forename: Margit
authors.initials: M
authors.lastname: Laimer
mesh_terms: D000485:Allergens / Q000235:genetics*; D005512:Food Hypersensitivity; D005638:Fruit / Q000235:genetics* / Q000276:immunology*; D018506:Gene Expression Regulation, Plant; D023281:Genomics; D006801:Humans; D005810:Multigene Family
chemical_list: D000485:Allergens