title: The association between circulating levels of antimüllerian hormone and follicle number, androgens, and menstrual cycle characteristics in young women.
abstract: OBJECTIVE
  To investigate the association between serum antimüllerian hormone (AMH) and other reproductive parameters in young women.
  
  
  METHODS
  Cross-sectional study.
  
  
  METHODS
  University hospital.
  
  
  METHODS
  Population-based cohort of 256 women: 180 were users and 76 were nonusers of hormonal contraceptives.
  
  
  METHODS
  None.
  
  
  METHODS
  Antral follicles, androgens, age at menarche, and duration and regularity of menstrual cycle.
  
  
  RESULTS
  AMH levels were lower among users of hormonal contraceptives compared to nonusers. Among nonusers, women with AMH levels in the upper tertile had 55% (95% confidence interval [CI]: 22%-99%) higher levels of total T and 8% (95% CI = 2%-15%) longer menstrual cycles than women with AMH levels in the lower tertile. An increase of 1 ng/mL in AMH was associated with 45% (95% CI = 6%-97%) higher prevalence of irregular menstrual cycles. These associations were not seen among users of hormonal contraceptives. A strong relationship between AMH and follicle number was found in both users and nonusers.
  
  
  CONCLUSIONS
  AMH measurements were found to be applicable in evaluation of the reproductive function of young women. However, there may be differences in the way that serum AMH levels can be interpreted depending on whether the woman uses hormonal contraceptives or not.
authors.affiliation: Department of Occupational Medicine, Aarhus University Hospital, Aarhus, Denmark. susankst@rm.dk
authors.forename: Susanne Lund
authors.initials: SL
authors.lastname: Kristensen
authors.forename: Cecilia Høst
authors.initials: CH
authors.lastname: Ramlau-Hansen
authors.forename: Claus Yding
authors.initials: CY
authors.lastname: Andersen
authors.forename: Erik
authors.initials: E
authors.lastname: Ernst
authors.forename: Sjurdur Frodi
authors.initials: SF
authors.lastname: Olsen
authors.forename: Jens Peter
authors.initials: JP
authors.lastname: Bonde
authors.forename: Anne
authors.initials: A
authors.lastname: Vested
authors.forename: Gunnar
authors.initials: G
authors.lastname: Toft
mesh_terms: D000367:Age Factors; D054304:Anti-Mullerian Hormone / Q000097:blood*; D015415:Biomarkers / Q000097:blood; D003271:Contraceptive Agents, Female / Q000627:therapeutic use; D003718:Denmark; D005260:Female; D006785:Hospitals, University; D006801:Humans; D016014:Linear Models; D008597:Menstrual Cycle / Q000097:blood* / Q000187:drug effects; D006080:Ovarian Follicle / Q000000981:diagnostic imaging / Q000187:drug effects / Q000378:metabolism*; D012098:Reproduction; D013739:Testosterone / Q000097:blood*; D014463:Ultrasonography; D055815:Young Adult
chemical_list: D015415:Biomarkers; D003271:Contraceptive Agents, Female; D013739:Testosterone; D054304:Anti-Mullerian Hormone