title: Ultrastructural characteristics of solid pseudopapillary tumors of the pancreas.
abstract: We carried out an electron microscopic study of solid pseudopapillary tumors of the pancreas (operation material) from 15 patients. Two cell types were distinguished. Type 1 cells had large oval nuclei, little changed mitochondria, and short fragments of the granular cytoplasmic reticulum. These cells formed mainly pseudopapillary structures around the vessels. Type 2 cells were characterized by pronounced nuclear polymorphism with specific "coffee bean" picture. The cytoplasm of these cells contained many large mitochondria with clarified matrix and often destroyed cristae; lipofuchsin granules were seen. The ultrastructural characteristics of the solid pseudopapillary tumor cells attest to their epithelial origin.
authors.affiliation: A. V. Vishnevsky Institute of Surgery, Ministry of Health Care and Social Development of Russian Federation, Moscow, Russia.
authors.forename: B V
authors.initials: BV
authors.lastname: Vtyurin
authors.forename: I A
authors.initials: IA
authors.lastname: Chekmaryova
authors.forename: E A
authors.initials: EA
authors.lastname: Dubova
authors.forename: M N
authors.initials: MN
authors.lastname: Podgornova
authors.forename: A I
authors.initials: AI
authors.lastname: Shchegolev
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D053144:Cell Nucleus Shape; D049109:Cell Proliferation; D048430:Cell Shape; D004730:Endothelium, Vascular / Q000473:pathology; D004847:Epithelial Cells / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D046529:Microscopy, Electron, Transmission; D008875:Middle Aged; D008928:Mitochondria / Q000473:pathology; D010190:Pancreatic Neoplasms / Q000098:blood supply / Q000378:metabolism / Q000473:pathology*; D055815:Young Adult