title: Simultaneous determination of geniposide, chlorogenic acid, crocin1, and rutin in crude and processed Fructus Gardeniae extracts by high performance liquid chromatography.
abstract: BACKGROUND
  Fructus Gardeniae, commonly used traditional Chinese medicine (TCM) called Zhizi in chinese, is derived from the dried fruit of Gardenia jasminoides Ellis of the Madder Family. To our knowledge, previously reported analytical methods were not developing for simultaneous determination of geniposide, chlorogenic acid, crocin1, and rutin in Fructus Gardeniae and its processed products of chaozheng pin (CZP) extracts.
  
  
  METHODS
  In this study, a HPLC method was developed for simultaneous determination four major active components in Fructus Gardeniae and its processed products.
  
  
  RESULTS
  The contents of geniposide, chlorogenic acid, crocin1, and rutin in Fructus Gardeniae samples analyzed were 2.492 - 4.242%, 0.162 - 0.407%, 0.417 -0.837%, and 0.116 - 0.251%, respectively.
  
  
  CONCLUSIONS
  The developed method can be applied to the intrinsic quality control of Fructus Gardeniae.
authors.affiliation: Department of Pharmaceutics, Shaoyang Medical College, Shangyang 422000, People's Republic of China.
authors.forename: Enhong
authors.initials: E
authors.lastname: Ouyang
authors.forename: Chengrong
authors.initials: C
authors.lastname: Zhang
authors.forename: Xiaomeng
authors.initials: X
authors.lastname: Li