title: Longitudinal monitoring of patients with Parkinson's disease via wearable sensor technology in the home setting.
abstract: Objective longitudinal monitoring of symptoms related motor fluctuations can provide valuable information for the clinical management of patients with Parkinson's disease. Current methods for long-term monitoring of motor fluctuations, such as patient diaries, are ineffective due to their time consuming and subjective nature. Researchers have shown that wearable sensors such as accelerometers can be used to gather objective information about a patient's motor symptoms. In this paper, we present preliminary results from our analysis on wearable sensor data gathered during longitudinal monitoring of 5 patients with PD. Our results indicate that it is possible to track longitudinal changes in motor symptoms by training a regression model based on Random Forests.
authors.affiliation: Department of Physical Medicine and Rehabilitation, Harvard Medical School, Spaulding Rehabilitation Hospital, Boston, MA 02114, USA. spatel19@partners.org
authors.forename: Shyamal
authors.initials: S
authors.lastname: Patel
authors.forename: Bor-Rong
authors.initials: BR
authors.lastname: Chen
authors.forename: Chiara
authors.initials: C
authors.lastname: Mancinelli
authors.forename: Sabrina
authors.initials: S
authors.lastname: Paganoni
authors.forename: Ludy
authors.initials: L
authors.lastname: Shih
authors.forename: Matt
authors.initials: M
authors.lastname: Welsh
authors.forename: Jennifer
authors.initials: J
authors.lastname: Dy
authors.forename: Paolo
authors.initials: P
authors.lastname: Bonato
mesh_terms: D000054:Acceleration; D056044:Actigraphy / Q000295:instrumentation*; D015374:Biosensing Techniques / Q000295:instrumentation*; D003020:Clothing; D004867:Equipment Design; D019544:Equipment Failure Analysis; D006699:Home Care Services; D008137:Longitudinal Studies; D018670:Monitoring, Ambulatory / Q000295:instrumentation*; D009068:Movement; D010300:Parkinson Disease / Q000175:diagnosis* / Q000503:physiopathology*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014481:United States