title: Assessment of gastric emptying function after gastrectomy using a real-time ¹³C breath test.
abstract: OBJECTIVE
  Effectiveness of gastric emptying after pylorus-preserving gastrectomy (PPG) remains unclear and a method for continuous assessment is needed. We assessed post-PPG gastric emptying with a continuous real-time ¹³C breath test (BreathID system, Oridion, Israel).
  
  
  METHODS
  Gastric emptying function was assessed by ¹³C breath test in 12 post-PPG patients and 9 post-distal gastrectomy (DG) patients. Continuous ¹³C-acetic acid breath test was performed using the BreathID system. Endoscopic study was also completed.
  
  
  RESULTS
  Diarrhea was significantly less common in PPG than DG patients (p=0.021). No other questionnaire items and endoscopic findings showed a significant difference. In the ¹³C-acetic acid breath test, the gastric emptying coefficient (GEC) was significantly greater in PPG than DG patients (p=0.025). No other test parameters showed a significant difference.
  
  
  CONCLUSIONS
  Emptying function in the remnant stomach was assessed successfully by the continuous ¹³C-acetic acid breath test. A greater GEC suggested better gastric emptying in PPG patients.
authors.affiliation: Department of Gastroenterological Surgery, Yokohama City University Graduate School of Medicine, Yokohama, Japan. yuki-homma@feel.ocn.ne.jp
authors.forename: Yuki
authors.initials: Y
authors.lastname: Homma
authors.forename: Hirotoshi
authors.initials: H
authors.lastname: Akiyama
authors.forename: Ryusei
authors.initials: R
authors.lastname: Matsuyama
authors.forename: Hirochika
authors.initials: H
authors.lastname: Makino
authors.forename: Yasunari
authors.initials: Y
authors.lastname: Sakamoto
authors.forename: Masahiko
authors.initials: M
authors.lastname: Inamori
authors.forename: Atsushi
authors.initials: A
authors.lastname: Nakajima
authors.forename: Shin
authors.initials: S
authors.lastname: Maeda
authors.forename: Kuniya
authors.initials: K
authors.lastname: Tanaka
authors.forename: Chikara
authors.initials: C
authors.lastname: Kunisaki
authors.forename: Itaru
authors.initials: I
authors.lastname: Endo
mesh_terms: D019342:Acetic Acid / Q000378:metabolism; D000368:Aged; D015415:Biomarkers / Q000378:metabolism; D001944:Breath Tests; D002247:Carbon Isotopes; D016009:Chi-Square Distribution; D003967:Diarrhea / Q000209:etiology / Q000503:physiopathology; D005260:Female; D005743:Gastrectomy / Q000009:adverse effects / Q000379:methods*; D005746:Gastric Emptying; D018530:Gastric Stump / Q000503:physiopathology*; D005773:Gastroscopy; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000175:diagnosis* / Q000378:metabolism / Q000503:physiopathology; D011237:Predictive Value of Tests; D013274:Stomach Neoplasms / Q000601:surgery*; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D015415:Biomarkers; D002247:Carbon Isotopes; D019342:Acetic Acid