title: Outcome in dogs with surgically resected oral fibrosarcoma (1997-2008).
abstract: Oral fibrosarcoma (FSA) is a common oral tumour in dogs, and historically reported survival times after surgical excision range from 7.0 to 12.2 months with local recurrence rates of 32-57%. The purpose of this retrospective study was to report outcome in a cohort of dogs with oral FSA treated with surgical excision with or without adjuvant radiation therapy. Twenty-nine dogs with a histological diagnosis of FSA arising from the oral cavity that underwent surgical resection of their oral FSA were included in this study. Twenty-one dogs were treated with surgical excision alone and eight dogs with both surgery and radiation therapy. The median progression-free interval was >653 days. The median survival time was 743 days. The 1- and 2-year survival rates were 87.7 and 57.8%, respectively. Seven (24.1%) dogs developed local recurrence. Seven dogs (24.1%) developed metastasis.
authors.affiliation: William R. Prichard Veterinary Medical Teaching Hospital, University of California-Davis, Davis, CA 95616, USA.
authors.forename: S A
authors.initials: SA
authors.lastname: Frazier
authors.forename: S M
authors.initials: SM
authors.lastname: Johns
authors.forename: J
authors.initials: J
authors.lastname: Ortega
authors.forename: A L
authors.initials: AL
authors.lastname: Zwingenberger
authors.forename: M S
authors.initials: MS
authors.lastname: Kent
authors.forename: G M
authors.initials: GM
authors.lastname: Hammond
authors.forename: C O
authors.initials: CO
authors.lastname: Rodriguez
authors.forename: M A
authors.initials: MA
authors.lastname: Steffey
authors.forename: K A
authors.initials: KA
authors.lastname: Skorupski
mesh_terms: D000818:Animals; D002140:California / Q000453:epidemiology; D003131:Combined Modality Therapy / Q000662:veterinary; D004283:Dog Diseases / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery*; D004285:Dogs; D005260:Female; D005354:Fibrosarcoma / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery / Q000662:veterinary*; D008297:Male; D009062:Mouth Neoplasms / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery / Q000662:veterinary*; D009364:Neoplasm Recurrence, Local / Q000453:epidemiology; D012189:Retrospective Studies; D012582:Schools, Veterinary; D016019:Survival Analysis; D016896:Treatment Outcome