title: Taking a rational approach in the treatment of avian mycobacteriosis.
abstract: Treatment for avian mycobacteriosis is still in its infancy and based on extrapolations from human medicine. The optimum drug choice, dose, or length of treatment has yet to be determined for most exotic animal species. Treatment should include multiple drugs for extended periods of time with appropriate monitoring of both drug levels and overall animal health. Risk to owners and handlers needs to be minimized through appropriate identification of the species of mycobacteri causing disease. More research is necessary on the pharmacokinetics of these drugs in other animal species and antibiotic resistance. Currently, euthanasia remains the most common action in the face of active mycobacteriosis.
authors.affiliation: College of Veterinary Medicine, Western University of Health Sciences, Pomona, CA 91766, USA. jbuur@westernu.edu
authors.forename: Jennifer
authors.initials: J
authors.lastname: Buur
authors.forename: Miguel D
authors.initials: MD
authors.lastname: Saggese
mesh_terms: D000818:Animals; D000829:Animals, Domestic; D000835:Animals, Wild; D000836:Animals, Zoo; D000900:Anti-Bacterial Agents / Q000493:pharmacokinetics / Q000627:therapeutic use*; D001717:Birds; D004305:Dose-Response Relationship, Drug; D024881:Drug Resistance, Bacterial; D004359:Drug Therapy, Combination / Q000662:veterinary; D037901:Euthanasia, Animal; D006801:Humans; D009162:Mycobacterium avium / Q000145:classification / Q000187:drug effects* / Q000302:isolation & purification; D013045:Species Specificity; D016896:Treatment Outcome; D014379:Tuberculosis, Avian / Q000188:drug therapy* / Q000378:metabolism
chemical_list: D000900:Anti-Bacterial Agents