title: Management of treatment with direct-acting antiviral (DAA) in clinical practice.
abstract: The triple therapy has brought about a genuine revolution in the care of patients with chronic hepatitis C virus infection, although achieving a high cure rate requires adding disciplines beyond the attending physician when confronted by a motivated patient. The treatment is complex because of the many parameters involved (such as fibrosis score, patient's history of previous antiviral treatment and viral kinetics during treatment). A working knowledge of drug interactions and contraindications for drugs other than antiviral therapy is required, as well as meticulous follow-up.
authors.affiliation: Unité hépato-gastroentérologie, Centre Hospitalier Pierre Oudot, Bourgoin-Jallieu, France. fontanges@orange.fr
authors.forename: Thierry
authors.initials: T
authors.lastname: Fontanges
mesh_terms: D000998:Antiviral Agents / Q000627:therapeutic use*; D019698:Hepatitis C, Chronic / Q000188:drug therapy*; D006801:Humans
chemical_list: D000998:Antiviral Agents