title: SIRT1 regulation-it ain't all NAD.
abstract: SIRT1 is a phylogenetically conserved energy sensor. The molecular mechanisms that regulate its catalytic activity, however, are incompletely understood. Gerhart-Hines et al. (2011) have identified β-adrenergic/cAMP signaling as a regulatory input that rapidly controls SIRT1 activity and fatty acid oxidation.
authors.affiliation: Howard Hughes Medical Institute, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095-1662, USA.
authors.forename: Lily C
authors.initials: LC
authors.lastname: Chao
authors.forename: Peter
authors.initials: P
authors.lastname: Tontonoz