title: A method for measuring the accuracy of multi-modal image fusion system for catheter-based cardiac interventions using a novel motion enabled targeting phantom.
abstract: Targeted stem cell therapy offers great potential for the repair of infarcted cardiac tissue following heart attack. Safe delivery of stem-cells via catheter based interventions remains a challenge. A multi-modal image fusion approach has been considered for safe targeting of myocardial infarct border zones. In this paper we present an apparatus and method for measuring the accuracy of catheter-based injections using a multi-modal image fusion system. We also present results of the accuracy of our image fusion system under varying levels of cardio-respiratory motion.
authors.affiliation: University of Wisconsin, Madison, WI 53792, USA. hatt@ wisc.edu
authors.forename: Charles R
authors.initials: CR
authors.lastname: Hatt
authors.forename: Douglas
authors.initials: D
authors.lastname: Stanton
authors.forename: Vijay
authors.initials: V
authors.lastname: Parthasarathy
authors.forename: Ameet K
authors.initials: AK
authors.lastname: Jain
authors.forename: Amish N
authors.initials: AN
authors.lastname: Raval
mesh_terms: D000465:Algorithms; D000818:Animals; D006328:Cardiac Catheterization / Q000379:methods; D002404:Catheterization; D057785:Catheters; D004867:Equipment Design; D006321:Heart / Q000502:physiology; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D021621:Imaging, Three-Dimensional / Q000379:methods; D009682:Magnetic Resonance Spectroscopy; D009038:Motion; D009203:Myocardial Infarction / Q000473:pathology; D019047:Phantoms, Imaging; D011142:Polyvinyl Alcohol / Q000737:chemistry; D015203:Reproducibility of Results; D012119:Respiration; D013234:Stem Cells / Q000166:cytology; D013552:Swine
chemical_list: D011142:Polyvinyl Alcohol