title: An integrated open-cavity system for magnetic bead separation and manipulation.
abstract: Superparamagnetic beads are generally used in biomedical assays to manipulate, maneuver, separate, and transport bio-materials. We present a low-cost integrated system designed in bulk 0.5 μm process to automate the manipulation and separation process of magnetic beads. The system consists of an 8 × 8 coil-array suitable for a single bead manipulation, or collaborative manipulation using pseudoparallel executions. The size of a single coil is 30 μm × 30 μm and the driver DC current source supports 8 different levels up to 1.5 mA. The total power consumption of the entire system is 9 mW when running at full power and it occupies an area of 248 μm × 248 μm.
authors.affiliation: Department of Electrical and Computer Engineering, Michigan State University, East Lansing, MI 48824, USA. asd1815@egr.msu.edu
authors.forename: Faisal T
authors.initials: FT
authors.lastname: Abu-Nimeh
authors.forename: Fathi M
authors.initials: FM
authors.lastname: Salem
mesh_terms: D003198:Computer Simulation; D004560:Electricity; D004581:Electronics; D020342:Finite Element Analysis; D008280:Magnetics / Q000379:methods*; D008670:Metals / Q000737:chemistry; D008863:Microspheres; D010087:Oxides / Q000737:chemistry; D012666:Semiconductors; D014741:Video Recording
chemical_list: D008670:Metals; D010087:Oxides