title: Feasibility and construct validity of PROMIS and "legacy" instruments in an academic scleroderma clinic.
abstract: OBJECTIVE
  The National Institutes of Health Patient-Reported Outcomes Measurement Information System (PROMIS) roadmap initiative is a cooperative group program of research designed to develop, evaluate, and standardize item banks to measure patient-reported outcomes relevant across medical conditions. The objective of the current study was to assess feasibility and evaluation of the construct validity of PROMIS item banks versus legacy measures in an observational study in systemic sclerosis (SSc). We hypothesized that the PROMIS item banks can be administered in a clinical setting if there is adequate staff support without disrupting the flow of clinic.
  
  
  METHODS
  Patients with SSc in a single academic center completed computerized adaptive test (CAT) administered PROMIS item banks during the clinic visit and legacy measures (using paper and pencil). The construct validity of PROMIS items was evaluated by examining correlations with corresponding legacy measures using multitrait-multimethod analysis.
  
  
  RESULTS
  Participants consisted of 143 SSc patients with an average age of 51.5 years; 71% were female and 68% were white. The average number of items completed for each CAT-administered item bank ranged from 5 to 8 (69 CAT items per patient), and the average time to complete each CAT-administered item bank ranged from 48 seconds to 1.9 minutes per patient (average time = 11.9 minutes/per patient for 11 banks). All correlations between PROMIS domains and respective legacy measures were large and in the hypothesized direction (ranged from 0.61 to 0.82).
  
  
  CONCLUSIONS
  Our study supports the construct validity of the CAT-administered PROMIS item banks and shows that they can be administered successfully in a clinic with support staff. Future studies should assess the feasibility of PROMIS item banks in a busy clinical practice.
authors.affiliation: Division of Rheumatology, University of Michigan, Ann Arbor, MI 48106, USA. khannad@med.umich.edu
authors.forename: Dinesh
authors.initials: D
authors.lastname: Khanna
authors.forename: Paul
authors.initials: P
authors.lastname: Maranian
authors.forename: Nan
authors.initials: N
authors.lastname: Rothrock
authors.forename: David
authors.initials: D
authors.lastname: Cella
authors.forename: Richard
authors.initials: R
authors.lastname: Gershon
authors.forename: Puja P
authors.initials: PP
authors.lastname: Khanna
authors.forename: Brennan
authors.initials: B
authors.lastname: Spiegel
authors.forename: Daniel E
authors.initials: DE
authors.lastname: Furst
authors.forename: Phil J
authors.initials: PJ
authors.lastname: Clements
authors.forename: Amber
authors.initials: A
authors.lastname: Bechtel
authors.forename: Ron D
authors.initials: RD
authors.lastname: Hays
mesh_terms: D000368:Aged; D000554:Ambulatory Care Facilities; D005240:Feasibility Studies; D005260:Female; D006304:Health Status; D006801:Humans; D008297:Male; D008603:Mental Health; D008875:Middle Aged; D009316:National Institutes of Health (U.S.); D017063:Outcome Assessment, Health Care / Q000379:methods*; D011594:Psychometrics; D011788:Quality of Life; D015203:Reproducibility of Results; D012595:Scleroderma, Systemic / Q000503:physiopathology / Q000523:psychology*; D011795:Surveys and Questionnaires; D013997:Time Factors; D014481:United States