title: Zinc-mediated highly α-regioselective prenylation of imines with prenyl bromide.
abstract: A highly α-regioselective prenylation of imines has been successfully developed. The efficiency of this approach is confirmed by a wide range of imines including N- and C-aryl aldimines, N-alkyl aldimines, C-alkyl aldimines, and N- and C-aryl ketimines. The approach uses prenyl bromide as the prenyl source and inexpensive and convenient zinc as the mediator as well as environmentally benign 1,3-dimethyl-2-imidazolidinone (DMI) as the solvent.
authors.affiliation: School of Chemistry and Chemical Engineering, and Jiangsu Key Laboratory of Green Synthetic Chemistry for Functional Materials, Xuzhou Normal University, Xuzhou 221116, Jiangsu, China. lmzhao@xznu.edu.cn
authors.forename: Li-Ming
authors.initials: LM
authors.lastname: Zhao
authors.forename: Shu-Qing
authors.initials: SQ
authors.lastname: Zhang
authors.forename: Hai-Shan
authors.initials: HS
authors.lastname: Jin
authors.forename: Li-Jing
authors.initials: LJ
authors.lastname: Wan
authors.forename: Fei
authors.initials: F
authors.lastname: Dou