title: [Contribution of polymorphic variants of the genes of xenobiotic transformation enzymes, antioxidative defense, and DNA repair to the development of individual predisposition to hepatobiliary and reproductive system diseases in petrochemical workers].
abstract: The paper gives the basic results of studying the polymorphic loci of the genes of xenobiotic transformation enzymes, antioxidative defense, and DNA repair in petrochemical workers. Polymerase chain reaction-restriction fragment length polymorphism assay was used to identify markers of the predisposition to the development of toxic hepatitis in men and impaired reproduction in women.
authors.forename: T V
authors.initials: TV
authors.lastname: Viktorova
authors.forename: O V
authors.initials: OV
authors.lastname: Kochetova
authors.forename: K F
authors.initials: KF
authors.lastname: Safina
authors.forename: M K
authors.initials: MK
authors.lastname: Gaĭnullina
authors.forename: L Z
authors.initials: LZ
authors.lastname: Akhmadishina
authors.forename: G F
authors.initials: GF
authors.lastname: Korytina
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000975:Antioxidants / Q000378:metabolism*; D001660:Biliary Tract Diseases / Q000453:epidemiology / Q000209:etiology / Q000235:genetics; D001711:Biotransformation / Q000235:genetics; D016022:Case-Control Studies; D002617:Chemical Industry; D056486:Chemical and Drug Induced Liver Injury / Q000453:epidemiology / Q000209:etiology / Q000235:genetics; D004260:DNA Repair / Q000235:genetics*; D005260:Female; D005787:Gene Frequency; D020022:Genetic Predisposition to Disease; D005831:Genital Diseases, Female / Q000453:epidemiology / Q000209:etiology / Q000235:genetics; D006801:Humans; D008875:Middle Aged; D009784:Occupational Diseases / Q000201:enzymology* / Q000453:epidemiology / Q000209:etiology / Q000235:genetics*; D010578:Petroleum; D011110:Polymorphism, Genetic; D012426:Russia; D015262:Xenobiotics / Q000493:pharmacokinetics* / Q000633:toxicity; D055815:Young Adult
chemical_list: D000975:Antioxidants; D010578:Petroleum; D015262:Xenobiotics