title: Green chemistry and the evolution of flow analysis. A review.
abstract: Flow analysis has achieved its majority as a well-established tool to solve analytical problems. Evolution of flow-based approaches has been analyzed by diverse points of view, including historical aspects, the commutation concept and the impact on analytical methodologies. In this overview, the evolution of flow analysis towards green analytical chemistry is demonstrated by comparing classical procedures implemented with different flow approaches. The potential to minimize reagent consumption and waste generation and the ability to implement processes unreliable in batch to replace toxic chemicals are also emphasized. Successful applications of greener approaches in flow analysis are also discussed, focusing on the last 10 years.
authors.affiliation: Departamento de Ciências Exatas-Química, Escola Superior de Agricultura Luiz de Queiroz, Universidade de São Paulo, Piracicaba, SP, Brazil.
authors.forename: Wanessa R
authors.initials: WR
authors.lastname: Melchert
authors.forename: Boaventura F
authors.initials: BF
authors.lastname: Reis
authors.forename: Fábio R P
authors.initials: FR
authors.lastname: Rocha
mesh_terms: D004787:Environmental Pollution / Q000517:prevention & control; D017022:Flow Injection Analysis / Q000295:instrumentation* / Q000379:methods*; D055772:Green Chemistry Technology / Q000379:methods*; D007220:Industrial Waste / Q000517:prevention & control; D046210:Microfluidic Analytical Techniques / Q000379:methods*; D008904:Miniaturization / Q000295:instrumentation / Q000379:methods; D009930:Organic Chemicals / Q000032:analysis / Q000633:toxicity; D012997:Solvents / Q000032:analysis / Q000633:toxicity
chemical_list: D007220:Industrial Waste; D009930:Organic Chemicals; D012997:Solvents