title: Detection of human bocavirus in the cerebrospinal fluid of children with encephalitis.
abstract: We report 4 children with encephalitis associated with human bocavirus (HBoV) 1 or 2. All children were severely underweight, and 2 died; 1 of them had a matching HBoV2 nucleotide sequence isolated from serum and bocavirus like particles in the cerebrospinal fluid that were observed with electron microscopy. No further pathogens were detected in the cerebrospinal fluid of these patients.
authors.affiliation: Department of Microbiology, Faculty of Medicine, Oita University, Yufu, Japan.
authors.forename: Marcelo Takahiro
authors.initials: MT
authors.lastname: Mitui
authors.forename: S M Shahnawaz Bin
authors.initials: SM
authors.lastname: Tabib
authors.forename: Takashi
authors.initials: T
authors.lastname: Matsumoto
authors.forename: Wahida
authors.initials: W
authors.lastname: Khanam
authors.forename: Selim
authors.initials: S
authors.lastname: Ahmed
authors.forename: Daisuke
authors.initials: D
authors.lastname: Mori
authors.forename: Nasima
authors.initials: N
authors.lastname: Akhter
authors.forename: Kentaro
authors.initials: K
authors.lastname: Yamada
authors.forename: Luthful
authors.initials: L
authors.lastname: Kabir
authors.forename: Akira
authors.initials: A
authors.lastname: Nishizono
authors.forename: Maria
authors.initials: M
authors.lastname: Söderlund-Venermo
authors.forename: Kamruddin
authors.initials: K
authors.lastname: Ahmed
mesh_terms: D002555:Cerebrospinal Fluid / Q000821:virology*; D002648:Child; D002675:Child, Preschool; D004279:DNA, Viral / Q000737:chemistry / Q000235:genetics; D018792:Encephalitis, Viral / Q000175:diagnosis* / Q000821:virology; D005260:Female; D056661:Human bocavirus / Q000302:isolation & purification*; D006801:Humans; D007223:Infant; D008297:Male; D008854:Microscopy, Electron; D008969:Molecular Sequence Data; D010322:Parvoviridae Infections / Q000175:diagnosis* / Q000821:virology; D017422:Sequence Analysis, DNA; D014771:Virion / Q000648:ultrastructure
chemical_list: D004279:DNA, Viral