title: A multiple-input multiple-output system for modeling the cardiac dynamics.
abstract: We describe the dynamics of the cardiovascular system by finding the input-output relationships in the state space of a functional cardiac model, based on state equations and observability criteria of control theory. The unit step response of the multiple-input multiple-output system model illustrates the damping effect of the arterial wall to the pulsatility of the heart. Our results show that hypertensive patients exhibit a lower inertia of the blood flow.
authors.affiliation: Universidad Nacional del Nordeste, Corrientes, Argentina. jemonzon@unne.edu.ar
authors.forename: Jorge E
authors.initials: JE
authors.lastname: Monzon
authors.forename: Carlos Alvarez
authors.initials: CA
authors.lastname: Picaza
authors.forename: Maria I
authors.initials: MI
authors.lastname: Pisarello
mesh_terms: D001158:Arteries / Q000502:physiology*; D001783:Blood Flow Velocity; D001794:Blood Pressure; D003198:Computer Simulation; D006321:Heart / Q000503:physiopathology*; D006801:Humans; D006973:Hypertension / Q000503:physiopathology*; D008955:Models, Cardiovascular; D011673:Pulsatile Flow