title: [Effect of sacha inchi oil (plukenetia volúbilis l) on the lipid profile of patients with hyperlipoproteinemia].
abstract: We performed a pilot, experimental, open study in order to know the effect, effective dosage and secondary effects of sacha inchi´s (Plukenetia Huallabamba) [corrected] oil on the lipid profiles of patients with hypercholesterolemia. We included 24 patients of ages 35 to 75, to whom we measured total cholesterol (TC), HDL, triglycerides (Tg), glucose (G), non-esterified fatty acids (NEFA) and insulin (I) levels in blood, then we randomized them to receive sacha inchi oil orally 5 ml or 10 ml of a suspension of sacha inchi oil (2gr/5ml) for four months. The oil intake produced a decrease in the mean values of TC, and NEFA, and a rise in HDL in both subgroups. The subgroup receiving 10 ml was associated to an increase in the insulin levels. Sacha inchi oil appears to have beneficial effects on the lipid profile of patients with dyslipidemia, but their efficacy and security should be evaluated in randomized clinical trials.
authors.affiliation: Instituto de Investigaciones Clínicas, Universidad Nacional Mayor de San Marcos, Lima, Perú. faustogarmendia@yahoo.com
authors.forename: Fausto
authors.initials: F
authors.lastname: Garmendia
authors.forename: Rosa
authors.initials: R
authors.lastname: Pando
authors.forename: Gerardo
authors.initials: G
authors.lastname: Ronceros
mesh_terms: D000328:Adult; D000368:Aged; D002784:Cholesterol / Q000097:blood*; D019665:Euphorbiaceae; D005260:Female; D006801:Humans; D006937:Hypercholesterolemia / Q000097:blood* / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D008517:Phytotherapy; D010865:Pilot Projects; D010938:Plant Oils / Q000627:therapeutic use*; D014280:Triglycerides / Q000145:classification*
chemical_list: D010938:Plant Oils; D014280:Triglycerides; D002784:Cholesterol