title: [Optical coherence tomography in diagnosis of intracranial hypertension in children].
abstract: Intracranial hypertension (IH) is important cause of optic disc edema. It is essential to distinguish the primary and secondary causes of IH. Persistent increasement of intracranial pressure over 200-250 mmH2O is caused by impairment of the balance between production and absorption of cerebrospinal fluid. Though the exact mechanism of IH is still unknown.
  
  
  OBJECTIVE
  Assessment of usefulness of spectral optical coherence tomography with dual beam eye tracking (SLO/OCT) in diagnosis of intracranial hypertension in children.
  
  
  METHODS
  4 children (at the age of 3-12 years) with IH underwent an comprehensive ophthalmological examination, including visual acuity testing (Snellen charts), color vision (Ishihara charts), evaluation of anterior and posterior segment of the eye in slit lamp. On SLO/OCT (Spectralis, Heidelberg) scans RNFL profile of the optic disc was assessed at admission day and after 8 weeks of treatment with oral diuretics. In all patients MRI of the central nervous system was performed.
  
  
  RESULTS
  In all children best corrected visual acuity and MRI scans were normal. 3 of 4 patients had secondary IH. Median global RNFL was 273 microm at admission day. In 3 of 4 children remission of optic disc edema was observed after 8 weeks of treatment with diuretics - median global RNFL was 138 microm.
  
  
  CONCLUSIONS
  Diagnosis of intracranial hypertension requires interdisciplinary cooperation. SLO/OCT is useful in monitoring remission of the optic disc edema.
authors.affiliation: Z Kliniki Okulistyki Dzieciecej z Ośrodkiem Leczenia Zeza Uniwersytetu Medycznego w Białymstoku.
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Mrugacz
authors.forename: Michał
authors.initials: M
authors.lastname: Szumiński
authors.forename: Alina
authors.initials: A
authors.lastname: Bakunowicz-Łazarczyk
mesh_terms: D002648:Child; D002675:Child, Preschool; D004232:Diuretics / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D019586:Intracranial Hypertension / Q000175:diagnosis* / Q000188:drug therapy*; D007429:Intraocular Pressure; D008297:Male; D011044:Poland; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D041623:Tomography, Optical Coherence / Q000379:methods*; D016896:Treatment Outcome; D014787:Vision Tests / Q000379:methods*; D014792:Visual Acuity; D014794:Visual Fields
chemical_list: D004232:Diuretics