title: Commentary: The evolution of methods to assess the effects of treatments, illustrated by the development of treatments for diphtheria, 1825-1918.
authors.affiliation: Pharmacoepidemiology and Infectious Diseases Unit, Institut Pasteur/UVSQ EA 4499/Inserm U657, 25, rue du Dr Roux, F- 75724 Paris Cedex 15, France. annick.opinel@pasteur.fr
authors.forename: Annick
authors.initials: A
authors.lastname: Opinel
authors.forename: Ulrich
authors.initials: U
authors.lastname: Tröhler
authors.forename: Christian
authors.initials: C
authors.lastname: Gluud
authors.forename: Gabriel
authors.initials: G
authors.lastname: Gachelin
authors.forename: George Davey
authors.initials: GD
authors.lastname: Smith
authors.forename: Scott Harris
authors.initials: SH
authors.lastname: Podolsky
authors.forename: Iain
authors.initials: I
authors.lastname: Chalmers
mesh_terms: D004165:Diphtheria / Q000266:history* / Q000628:therapy; D004166:Diphtheria Antitoxin / Q000266:history*; D004168:Diphtheria Toxoid / Q000266:history* / Q000627:therapeutic use; D049672:History, 19th Century; D049673:History, 20th Century; D006801:Humans; D007106:Immune Sera / Q000008:administration & dosage / Q000266:history*; D007440:Intubation / Q000266:history*; D010043:Outcome and Process Assessment, Health Care; D014140:Tracheotomy / Q000266:history*
chemical_list: D004166:Diphtheria Antitoxin; D004168:Diphtheria Toxoid; D007106:Immune Sera