title: [Effect of cardiovascular drugs on vasodilating endothelial function in animals with experimental deficiency of sex hormones].
abstract: The influence of various cardiovascular drugs, including ACE inhibitors (lisinopril), beta-adrenoblockers (bisoprolol, nebivolol), calcium inhibitors (nifedipine), cholesterol-lowering drugs (simvastatin), and heparinoids (sulodexide), on the vasodilating endothelial function has been studied in animals with experimental deficiency of sex hormones. According to the expressiveness of a positive effect on endothelium-dependent vasodilatation in castrated rats, the tested drugs can be arranged in the following sequence: sulodexide > lisinopril > or = simvastatin > or = nebivolol > bisoprolol > nifedipine.
authors.forename: A V
authors.initials: AV
authors.lastname: Voronkov
authors.forename: I N
authors.initials: IN
authors.lastname: Tiurenkov
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000494:pharmacology; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000494:pharmacology; D000818:Animals; D000924:Anticholesteremic Agents / Q000494:pharmacology; D000925:Anticoagulants / Q000494:pharmacology; D002121:Calcium Channel Blockers / Q000494:pharmacology; D002318:Cardiovascular Diseases / Q000188:drug therapy* / Q000503:physiopathology; D004195:Disease Models, Animal; D004730:Endothelium, Vascular / Q000187:drug effects*; D005260:Female; D012739:Gonadal Steroid Hormones / Q000172:deficiency*; D006439:Hemodynamics / Q000187:drug effects*; D007044:Hysterectomy; D009569:Nitric Oxide / Q000378:metabolism; D051381:Rats; D014664:Vasodilation / Q000187:drug effects*; D014665:Vasodilator Agents / Q000494:pharmacology
chemical_list: D000319:Adrenergic beta-Antagonists; D000806:Angiotensin-Converting Enzyme Inhibitors; D000924:Anticholesteremic Agents; D000925:Anticoagulants; D002121:Calcium Channel Blockers; D012739:Gonadal Steroid Hormones; D014665:Vasodilator Agents; D009569:Nitric Oxide