title: Elastic registration based on particle filter in radiotherapy images with brain deformations.
abstract: This paper presents the evaluation of the accuracy of an elastic registration algorithm, based on the particle filter and an optical flow process. The algorithm is applied in brain CT and MRI simulated image datasets, and MRI images from a real clinical radiotherapy case. To validate registration accuracy, standard indices for registration accuracy assessment were calculated: the dice similarity coefficient (DICE), the average symmetric distance (ASD) and the maximal distance between pixels (Dmax). The results showed that this registration process has good accuracy, both qualitatively and quantitatively, suggesting that this method may be considered as a good new option for radiotherapy applications like patient's follow up treatment.
authors.affiliation: Institute of Molecular Bioimaging and Physiology, IBFM-CNR, Milan, Italy. armero83@gmail.com
authors.forename: A R
authors.initials: AR
authors.lastname: Mejia-Rodriguez
authors.forename: E R
authors.initials: ER
authors.lastname: Arce-Santana
authors.forename: E
authors.initials: E
authors.lastname: Scalco
authors.forename: D
authors.initials: D
authors.lastname: Tresoldi
authors.forename: M O
authors.initials: MO
authors.lastname: Mendez
authors.forename: A M
authors.initials: AM
authors.lastname: Bianchi
authors.forename: G M
authors.initials: GM
authors.lastname: Cattaneo
authors.forename: G
authors.initials: G
authors.lastname: Rizzo
mesh_terms: D000465:Algorithms; D001921:Brain / Q000000981:diagnostic imaging*; D003198:Computer Simulation; D004548:Elasticity; D006801:Humans; D008279:Magnetic Resonance Imaging; D011857:Radiographic Image Interpretation, Computer-Assisted / Q000379:methods*; D014057:Tomography, X-Ray Computed / Q000379:methods*