title: [Strategy of surgical treatment for ischemic heart disease].
abstract: The efficacy of regenerative cell therapy as strategy of cardiac functional recovery in patients with end-stage heart failure has been recently reported, and clinical applications of autologous skeletal myoblast cell transplantation has been already started in Europe and U.S. We developed cell-sheet technology with a temperature-responsive culture dish, which enabled cell-to-cell junction to retain, and started a clinical study of cardiac regenerative therapy using autologous skeletal myoblast cell sheet implantation.
authors.affiliation: Department of Cardiovascular Surgery, Graduate School of Medicine, Osaka University.
authors.forename: Yoshiki
authors.initials: Y
authors.lastname: Sawa
mesh_terms: D016027:Heart Transplantation; D006353:Heart-Assist Devices; D006801:Humans; D032386:Myoblasts, Cardiac / Q000637:transplantation*; D017202:Myocardial Ischemia / Q000628:therapy*