title: Surgical soft tissue closure of severe diabetic foot infections: a combination of biologics, negative pressure wound therapy, and skin grafting.
abstract: Creative surgical strategies are often warranted for long-term closure of diabetic foot wounds. This article provides a case report describing the successive use of negative pressure wound therapy, advanced biologics, and split thickness skin grafting for healing an extensive surgical wound. Although the success of these therapies is enticing, their use should be based on careful patient selection in a multidisciplinary setting.
authors.affiliation: Division of Podiatric Medicine and Surgery, Department of Orthopaedic Surgery, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.
authors.forename: Crystal L
authors.initials: CL
authors.lastname: Ramanujam
authors.forename: Thomas
authors.initials: T
authors.lastname: Zgonis
mesh_terms: D001684:Biological Dressings; D002809:Chondroitin Sulfates; D003094:Collagen; D003131:Combined Modality Therapy; D017719:Diabetic Foot / Q000601:surgery / Q000628:therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D054843:Negative-Pressure Wound Therapy; D016038:Skin Transplantation; D018461:Soft Tissue Infections / Q000601:surgery / Q000628:therapy*; D058106:Wound Closure Techniques; D014945:Wound Healing
chemical_list: C114835:integra artificial skin; D002809:Chondroitin Sulfates; D003094:Collagen