title: Open-access MIMIC-II database for intensive care research.
abstract: The critical state of intensive care unit (ICU) patients demands close monitoring, and as a result a large volume of multi-parameter data is collected continuously. This represents a unique opportunity for researchers interested in clinical data mining. We sought to foster a more transparent and efficient intensive care research community by building a publicly available ICU database, namely Multiparameter Intelligent Monitoring in Intensive Care II (MIMIC-II). The data harnessed in MIMIC-II were collected from the ICUs of Beth Israel Deaconess Medical Center from 2001 to 2008 and represent 26,870 adult hospital admissions (version 2.6). MIMIC-II consists of two major components: clinical data and physiological waveforms. The clinical data, which include patient demographics, intravenous medication drip rates, and laboratory test results, were organized into a relational database. The physiological waveforms, including 125 Hz signals recorded at bedside and corresponding vital signs, were stored in an open-source format. MIMIC-II data were also deidentified in order to remove protected health information. Any interested researcher can gain access to MIMIC-II free of charge after signing a data use agreement and completing human subjects training. MIMIC-II can support a wide variety of research studies, ranging from the development of clinical decision support algorithms to retrospective clinical studies. We anticipate that MIMIC-II will be an invaluable resource for intensive care research by stimulating fair comparisons among different studies.
authors.affiliation: Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA, USA. joonlee@mit.edu
authors.forename: Joon
authors.initials: J
authors.lastname: Lee
authors.forename: Daniel J
authors.initials: DJ
authors.lastname: Scott
authors.forename: Mauricio
authors.initials: M
authors.lastname: Villarroel
authors.forename: Gari D
authors.initials: GD
authors.lastname: Clifford
authors.forename: Mohammed
authors.initials: M
authors.lastname: Saeed
authors.forename: Roger G
authors.initials: RG
authors.lastname: Mark
mesh_terms: D022126:Access to Information; D000328:Adult; D003422:Critical Care; D016208:Databases, Factual; D006801:Humans; D008991:Monitoring, Physiologic; D012106:Research; D058067:Wavelet Analysis