title: Long-term (up to 20 years) effects of 50-Hz magnetic field exposure on blood chemistry parameters in healthy men.
abstract: OBJECTIVE
  The potential effects of a chronic exposure to magnetic fields on blood chemistry in humanswere tested.
  
  
  METHODS
  We examined the nocturnal profiles and levels of the following blood parameters: electrolytes (sodium, potassium, chloride, calcium, magnesium, phosphorus), nonprotein nitrogenous compounds (uric acid, urea, creatinine), and glucose, in 15 men (38.0 ± 0.9 years) exposed chronically and daily for a period of 1-20 years, in the workplace and at home, to a 50-Hz magnetic field in search of any cumulative effect from those chronic conditions of exposure. The weekly geometric mean of individual exposures ranged from 0.1 to 2.6 μT. The results are compared to those obtained in our control group: 15 unexposed men of similar age (39.4 ± 1.2 years), with the same synchronization and physical activity that served as controls (individual exposures ranged from 0.004 to 0.092 μT). Blood samples were taken hourly from 20:00 h to 08:00 h.
  
  
  RESULTS
  This work shows that subjects exposed over a long period (up to 20 years) and on a daily basis to magnetic fields experienced significant changes in serum sodium, chloride, phosphorus and glucose where an effect for field-hour interaction was noted for exposures greater than 0.3 μT.
  
  
  CONCLUSIONS
  Our data suggest that long-term exposure to 50-Hzmagnetic fields (exposure>0.3 μT) in healthy men could induce some biological modifications of certain blood parameters, though their clinical relevance needs further investigation.
authors.affiliation: Chronobiology Unit, Fondation Ophtalmologique Adolphe de Rothschild, Paris, France. yvan.touitou@chronobiology.fr
authors.forename: Yvan
authors.initials: Y
authors.lastname: Touitou
authors.forename: Yasmina
authors.initials: Y
authors.lastname: Djeridane
authors.forename: Jacques
authors.initials: J
authors.lastname: Lambrozo
authors.forename: Françoise
authors.initials: F
authors.lastname: Camus
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D001786:Blood Glucose; D016022:Case-Control Studies; D003404:Creatinine / Q000097:blood; D004573:Electrolytes / Q000097:blood*; D006801:Humans; D060526:Magnetic Fields / Q000009:adverse effects; D008297:Male; D054526:Men's Health; D008875:Middle Aged; D016273:Occupational Exposure / Q000009:adverse effects; D014508:Urea / Q000097:blood; D014527:Uric Acid / Q000097:blood
chemical_list: D001786:Blood Glucose; D004573:Electrolytes; D014527:Uric Acid; D014508:Urea; D003404:Creatinine