title: Balloon type elasticity sensing for left ventricle of small laboratory animal.
abstract: This paper describes an elasticity sensing system for left ventricle of small laboratory animal. We first show the basic concept of the proposed method, where a ring shaped specimen is dilated by a balloon type probe using a pressure based control, and the elasticity of the specimen is estimated by using the stress and strain information. We introduce a dual cylinder model for approximating the strengths of the specimen's material and the balloon. Based on this model, we can derive Young's modulus of the specimen. After explaining the developed experimental system, we show a couple of experimental results using rats and mice, where HFPEF (Heart Failure Preserved Ejection Fraction) group can be distinguished from a normal group.
authors.affiliation: Department of Mechanical Engineering, Osaka University, 2-1 Yamadaoka, Suita, Japan. ishii@hh
authors.forename: Ryohei
authors.initials: R
authors.lastname: Ishii
authors.forename: Mitsuru
authors.initials: M
authors.lastname: Higashimori
authors.forename: Kenjiro
authors.initials: K
authors.lastname: Tadakuma
authors.forename: Makoto
authors.initials: M
authors.lastname: Kaneko
authors.forename: Shunsuke
authors.initials: S
authors.lastname: Tamaki
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Sakata
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Yamamoto
mesh_terms: D000818:Animals; D006328:Cardiac Catheterization / Q000295:instrumentation*; D002404:Catheterization / Q000295:instrumentation*; D003198:Computer Simulation; D055119:Elastic Modulus; D004867:Equipment Design; D019544:Equipment Failure Analysis; D006245:Hardness Tests / Q000295:instrumentation*; D006333:Heart Failure / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology*; D006352:Heart Ventricles / Q000503:physiopathology*; D051379:Mice; D008955:Models, Cardiovascular; D051381:Rats; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D018487:Ventricular Dysfunction, Left / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology*