title: In vitro antifungal activity of terpinen-4-ol, eugenol, carvone, 1,8-cineole (eucalyptol) and thymol against mycotoxigenic plant pathogens.
abstract: The aim of this study was to examine the effect of five naturally occurring compounds from essential oils on 10 different species of mycotoxigenic fungi involved in several plant diseases. The antifungal activities of terpinen-4-ol, eugenol, carvone, 1,8-cineole (eucalyptol) and thymol were observed in vitro on Fusarium subglutinans, Fusarium cerealis, Fusarium verticillioides, Fusarium proliferatum, Fusarium oxysporum, Fusarium sporotrichioides, Aspergillus tubingensis, Aspergillus carbonarius, Alternaria alternata and Penicillium sp. The naturally occurring compounds tested showed toxic effects on in vitro mycelium growth of all fungal species but with different level of potency. The results are encouraging for further investigations of in planta antifungal activities of these essential oils components.
authors.affiliation: CRA-GPG, Centro di ricerca per la Genomica e la Postgenomica Animale e Vegetale, Fiorenzuola d'Arda (PC), Italy.
authors.forename: C
authors.initials: C
authors.lastname: Morcia
authors.forename: M
authors.initials: M
authors.lastname: Malnati
authors.forename: V
authors.initials: V
authors.lastname: Terzi
mesh_terms: D000528:Alternaria / Q000187:drug effects / Q000378:metabolism; D001230:Aspergillus / Q000187:drug effects / Q000378:metabolism; D000081005:Cyclohexane Monoterpenes; D003511:Cyclohexanols / Q000009:adverse effects / Q000494:pharmacology; D000077591:Eucalyptol; D005054:Eugenol / Q000009:adverse effects / Q000494:pharmacology*; D005659:Fungicides, Industrial / Q000009:adverse effects / Q000494:pharmacology*; D005670:Fusarium / Q000187:drug effects / Q000254:growth & development / Q000378:metabolism; D018525:Germination / Q000187:drug effects; D001467:Hordeum / Q000187:drug effects / Q000254:growth & development; D025301:Hyphae / Q000187:drug effects / Q000378:metabolism; D020128:Inhibitory Concentration 50; D003904:Mitosporic Fungi / Q000187:drug effects* / Q000254:growth & development / Q000378:metabolism; D039821:Monoterpenes / Q000009:adverse effects / Q000494:pharmacology*; D009183:Mycotoxins / Q000378:metabolism; D009822:Oils, Volatile / Q000737:chemistry; D010407:Penicillium / Q000187:drug effects / Q000378:metabolism; D010935:Plant Diseases / Q000382:microbiology / Q000517:prevention & control; D012639:Seeds / Q000187:drug effects / Q000254:growth & development; D013729:Terpenes / Q000009:adverse effects / Q000494:pharmacology; D013943:Thymol / Q000009:adverse effects / Q000494:pharmacology*; D014255:Trichothecenes / Q000378:metabolism
chemical_list: D000081005:Cyclohexane Monoterpenes; D003511:Cyclohexanols; D005659:Fungicides, Industrial; D039821:Monoterpenes; D009183:Mycotoxins; D009822:Oils, Volatile; D013729:Terpenes; D014255:Trichothecenes; D013943:Thymol; D005054:Eugenol; C034019:terpinenol-4; C006923:carvone; C007262:deoxynivalenol; D000077591:Eucalyptol