title: [Role of selective decontamination in combined treatment of chronic anal fissure].
abstract: Effectiveness of selective decontamination in combined treatment of patients with chronic anal fissure and concomitant proctitis was studied in clinical randomized investigation including 103 patients. The etiologically significant flora colonizing the chronic defect of the anoderma does not coincide with the composition of feces microflora and is presented by anaerobic microorganisms or a combination of aerobes and anaerobes. It was established that topical etiotropic antibacterial therapy in combination with medicamentous sphincterotomy in the outpatient treatment resulted in quicker arrest of the pain syndrome, accelerated epithelization of the fissure and made the period of treatment 2 times shorter as compared with control.
authors.forename: N M
authors.initials: NM
authors.lastname: Grekova
authors.forename: E A
authors.initials: EA
authors.lastname: Maleva
authors.forename: V N
authors.initials: VN
authors.lastname: Bordunovskiĭ
authors.forename: Iu V
authors.initials: IuV
authors.lastname: Lebedeva
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D001419:Bacteria / Q000145:classification / Q000187:drug effects* / Q000302:isolation & purification; D002908:Chronic Disease; D003131:Combined Modality Therapy; D003666:Decontamination / Q000379:methods*; D005243:Feces / Q000382:microbiology; D005260:Female; D005401:Fissure in Ano / Q000188:drug therapy* / Q000382:microbiology* / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D000900:Anti-Bacterial Agents