title: [Occult mediastinal node involvement in non-small cell lung cancer after negative uptake on PET/CT: ripples through staging and therapy. Case report and critical review].
abstract: A 78-years old man, heavy smoker, with a persistent and hacking cough, was diagnosed with an adenocarcinoma of upper lobe of left lung. Clinical stage was defined as cT2N0M0 also on the basis of a negative (18)FDG-PET/TC. After lobectomy, pathological stage resulted, on the contrary, pT2N2M0. Because the considerable incidence of preoperative false negative uptakes of PET/TC for involvement of mediastinal lymph nodes, this case report is highlighted as emblematic, particularly in relation to post-operative treatment of early stage NSCLC.
authors.affiliation: Unità di Radioterapia Oncologica. Università Campus Bio-Medico, Roma, Italia.
authors.forename: L
authors.initials: L
authors.lastname: Trodella
authors.forename: F
authors.initials: F
authors.lastname: Salvati
authors.forename: M
authors.initials: M
authors.lastname: Martelli
authors.forename: P
authors.initials: P
authors.lastname: Mattia
authors.forename: P
authors.initials: P
authors.lastname: Graziano
authors.forename: E
authors.initials: E
authors.lastname: Ippolito
mesh_terms: D000368:Aged; D002289:Carcinoma, Non-Small-Cell Lung / Q000000981:diagnostic imaging* / Q000473:pathology / Q000556:secondary / Q000628:therapy; D005188:False Negative Reactions; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000628:therapy; D008207:Lymphatic Metastasis; D008297:Male; D008482:Mediastinum; D064847:Multimodal Imaging; D009367:Neoplasm Staging; D049268:Positron-Emission Tomography; D014057:Tomography, X-Ray Computed