title: Mycobacterial lesions in fish, amphibians, reptiles, rodents, lagomorphs, and ferrets with reference to animal models.
abstract: Mycobacteriosis is a serious disease across many animal species. Approximately more than 120 species are currently recognized in the genus Mycobacterium. This article describes the zoonotic potential of mycobacteria and mycobacteriosis in fish, amphibians, rodents, rabbits, and ferrets. It considers clinical signs; histology; molecular methods of identification, such as polymerase chain reaction and DNA sequencing; routes of infection; and disease progression. Studying the disease in animals may aid in understanding the pathogenesis of mycobacterial infections in humans and identify better therapy and preventative options such as vaccines.
authors.affiliation: Zoo/Exotic Pathology Service, West Sacramento, CA 95605, USA. DReavill@zooexotic.com
authors.forename: Drury R
authors.initials: DR
authors.lastname: Reavill
authors.forename: Robert E
authors.initials: RE
authors.lastname: Schmidt
mesh_terms: D000663:Amphibians; D000818:Animals; D000835:Animals, Wild / Q000382:microbiology*; D004269:DNA, Bacterial / Q000032:analysis*; D018450:Disease Progression; D005289:Ferrets; D005399:Fishes; D006801:Humans; D009161:Mycobacterium / Q000145:classification* / Q000472:pathogenicity*; D009164:Mycobacterium Infections / Q000382:microbiology / Q000635:transmission / Q000662:veterinary*; D011817:Rabbits; D012377:Rodentia; D013045:Species Specificity; D015047:Zoonoses
chemical_list: D004269:DNA, Bacterial