title: Evaluation of mineral trioxide aggregate (MTA) versus calcium hydroxide cement (Dycal(®) ) in the formation of a dentine bridge: a randomised controlled trial.
abstract: OBJECTIVE
  To assess the effectiveness of mineral trioxide aggregate (MTA) used as an indirect pulp-capping material in human molar and premolar teeth.
  
  
  METHODS
  We conducted a clinical evaluation of 60 teeth, which underwent an indirect pulp-capping procedure with either MTA or calcium hydroxide cement (Dycal(®) ). Calcium hydroxide was compared with MTA and the thickness of the newly formed dentine was measured at regular time intervals. The follow-up was at 3 and 6 months, and dentine formation was monitored by radiological measurements on digitised images using Mesurim Pro(®) software.
  
  
  RESULTS
  At 3 months, the clinical success rates of MTA and calcium hydroxide were 93% and 73%, respectively (P = 0.02). At 6 months, the success rate was 89.6% with MTA, and remained steady at 73% with calcium hydroxide (P = 0.63). The mean initial residual dentine thickness was 0.23 mm, and increased by 0.121 mm with MTA and by 0.136 mm with calcium hydroxide at 3 months. At 6 months, there was an increase of 0.235 mm with MTA and of 0.221 mm with calcium hydroxide.
  
  
  CONCLUSIONS
  A higher success rate was observed in the MTA group relative to the Dycal(®) group after 3 months, which was statistically significant. After 6 months, no statistically significant difference was found in the dentine thickness between the two groups. Additional histological investigations are needed to support these findings.
authors.affiliation: Institute of Dentistry, Route de l'Université, University Cheikh Anta Diop, Dakar, Senegal. fatou.leye@ucad.ed.sn
authors.forename: Fatou
authors.initials: F
authors.lastname: Leye Benoist
authors.forename: Fatou
authors.initials: F
authors.lastname: Gaye Ndiaye
authors.forename: Abdoul Wakhabe
authors.initials: AW
authors.lastname: Kane
authors.forename: Henri Michel
authors.initials: HM
authors.lastname: Benoist
authors.forename: Pierre
authors.initials: P
authors.lastname: Farge
mesh_terms: D000293:Adolescent; D000328:Adult; D017607:Aluminum Compounds / Q000494:pharmacology / Q000627:therapeutic use*; D001641:Bicuspid; D017610:Calcium Compounds / Q000494:pharmacology / Q000627:therapeutic use*; D002126:Calcium Hydroxide / Q000494:pharmacology / Q000627:therapeutic use*; D003782:Dental Pulp / Q000187:drug effects; D003785:Dental Pulp Capping / Q000379:methods*; D003809:Dentin, Secondary / Q000254:growth & development / Q000378:metabolism*; D004338:Drug Combinations; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D008903:Minerals / Q000494:pharmacology / Q000627:therapeutic use*; D008963:Molar; D010087:Oxides / Q000494:pharmacology / Q000627:therapeutic use*; D011446:Prospective Studies; D057872:Pulp Capping and Pulpectomy Agents / Q000494:pharmacology / Q000627:therapeutic use*; D017640:Silicates / Q000494:pharmacology / Q000627:therapeutic use*; D016037:Single-Blind Method; D055815:Young Adult
chemical_list: D017607:Aluminum Compounds; D017610:Calcium Compounds; D004338:Drug Combinations; D008903:Minerals; D010087:Oxides; D057872:Pulp Capping and Pulpectomy Agents; D017640:Silicates; C086631:mineral trioxide aggregate; C025702:Dycal; D002126:Calcium Hydroxide