title: Three-dimensional reconstruction of transcranial ultrasound images obtained through the temporal bone window using a helmet-mounted mechanical beam-steering device.
abstract: Transcranial sonography has been an increasingly widespread diagnostic tool for the diagnosis of neural diseases like Parkinson's disease. However, the utilization of modern 3D ultrasound techniques has been hampered by the acoustical barrier of the skull bones. We report the development of and preliminary results from an ultrasound helmet which uses mechanical beam-steering to allow 3-D reconstruction of deep brain structures such as the substantia nigra.
authors.affiliation: Pennsylvania State University, Electrical Engineering Department, University Park, PA 16802, USA. timgilmour@psu.edu
authors.forename: Timothy P
authors.initials: TP
authors.lastname: Gilmour
authors.forename: Thyagarajan
authors.initials: T
authors.lastname: Subramanian
mesh_terms: D004867:Equipment Design; D019544:Equipment Failure Analysis; D006260:Head Protective Devices; D006801:Humans; D007089:Image Enhancement / Q000295:instrumentation*; D021621:Imaging, Three-Dimensional / Q000295:instrumentation*; D055617:Micro-Electrical-Mechanical Systems / Q000295:instrumentation*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013701:Temporal Bone / Q000000981:diagnostic imaging*; D017585:Ultrasonography, Doppler, Transcranial / Q000295:instrumentation*