title: Weak and absent peristalsis.
abstract: BACKGROUND
  Weak and absent esophageal peristalsis are frequently encountered esophageal motility disorders, which may be associated with dysphagia and which may contribute to gastroesophageal reflux disease. Recently, rapid developments in the diagnostic armamentarium have taken place, in particular, in high-resolution manometry with or without concurrent intraluminal impedance monitoring.
  
  
  OBJECTIVE
  This article aims to review the current insights in the terminology, pathology, pathophysiology, clinical manifestations, diagnostic work-up,and management of weak and absent peristalsis.
authors.affiliation: Department of Gastroenterology and Hepatology, Academic Medical Centre, Amsterdam, The Netherlands. a.j.smout@amc.uva.nl
authors.forename: André
authors.initials: A
authors.lastname: Smout
authors.forename: Mark
authors.initials: M
authors.lastname: Fox
mesh_terms: D015154:Esophageal Motility Disorders; D006801:Humans; D008365:Manometry / Q000379:methods; D010528:Peristalsis / Q000502:physiology*