title: Decoding ensemble activity from neurophysiological recordings in the temporal cortex.
abstract: We study subjects with pharmacologically intractable epilepsy who undergo semi-chronic implantation of electrodes for clinical purposes. We record physiological activity from tens to more than one hundred electrodes implanted in different parts of neocortex. These recordings provide higher spatial and temporal resolution than non-invasive measures of human brain activity. Here we discuss our efforts to develop hardware and algorithms to interact with the human brain by decoding ensemble activity in single trials. We focus our discussion on decoding visual information during a variety of visual object recognition tasks but the same technologies and algorithms can also be directly applied to other cognitive phenomena.
authors.affiliation: Swartz Center for Theoretical Neuroscience, Harvard University and Children’s Hospital, Harvard Medical School, Boston, MA 02115, USA. gabriel.kreiman@tch.harvard.edu
authors.forename: Gabriel
authors.initials: G
authors.lastname: Kreiman
mesh_terms: D000465:Algorithms; D001931:Brain Mapping / Q000379:methods*; D003936:Diagnosis, Computer-Assisted / Q000379:methods*; D004569:Electroencephalography / Q000379:methods*; D004827:Epilepsy / Q000175:diagnosis* / Q000503:physiopathology*; D006801:Humans; D009415:Nerve Net / Q000503:physiopathology*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013702:Temporal Lobe / Q000503:physiopathology*