title: Rapid consecutive three-component coupling-Fiesselmann synthesis of luminescent 2,4-disubstituted thiophenes and oligothiophenes.
abstract: (Hetero)aroyl chlorides, alkynes, and ethyl 2-mercapto acetate can be reacted in a consecutive three-component synthesis to give 2,4-disubstituted thiophene 5-carboxylates in good to excellent yields. In the sense of a pseudo-five-component reaction highly blue luminescent symmetrical terthiophenes and a quinquethiophene can be synthesized in excellent yield.
authors.affiliation: Lehrstuhl für Organische Chemie, Institut für Organische Chemie und Makromolekulare Chemie, Heinrich-Heine-Universität Düsseldorf, Universitätsstrasse 1, D-40225, Düsseldorf, Germany.
authors.forename: Marco
authors.initials: M
authors.lastname: Teiber
authors.forename: Thomas J J
authors.initials: TJ
authors.lastname: Müller
mesh_terms: D000480:Alkynes / Q000138:chemical synthesis / Q000737:chemistry; D060326:Chemistry Techniques, Synthetic / Q000191:economics / Q000379:methods; D002712:Chlorides / Q000138:chemical synthesis / Q000737:chemistry; D049408:Luminescent Agents / Q000138:chemical synthesis / Q000737:chemistry*; D013876:Thiophenes / Q000138:chemical synthesis / Q000737:chemistry*; D013997:Time Factors
chemical_list: D000480:Alkynes; D002712:Chlorides; D049408:Luminescent Agents; D013876:Thiophenes