title: Cardiac markers of EIH athletes in ultramarathon.
abstract: This study aimed to investigate effects of a 100-km ultramarathon on cardiac markers of exercise-induced-hypertensive marathoners. 10 marathoners with exercise-induced hypertension and 10 normal marathoners participated in the study. Their blood samples were collected before starting, at 50 km, and after finishing the course (100 km). Creatinine kinase was more significantly increased in the exercise-induced-hypertensive group than in the normal group at 100 km (P<0.05). N-terminal pro-brain nutriuretic peptide was significantly increased in the exercise-induced-hypertensive group at 50 km and 10  km (P<0.05) which was significant being doubled compared to the normal group (P<0.05). Exercise-induced-hypertensive marathoners showed a significant triple-increase in C-Reactive protein at 100 km (P<0.05). In conclusion, although the exercise-induced-hypertensive runners did not have myocardial damage during the 100 km ultramarathon, they had higher myocardial stress and more damage in active muscles due to a bloodstream disability.
authors.affiliation: Inje University, Department of Rehabilitation Medicine, Seoul, Republic of Korea.
authors.forename: Y-J
authors.initials: YJ
authors.lastname: Kim
authors.forename: C-H
authors.initials: CH
authors.lastname: Kim
authors.forename: K-A
authors.initials: KA
authors.lastname: Shin
authors.forename: A-C
authors.initials: AC
authors.lastname: Kim
authors.forename: Y-H
authors.initials: YH
authors.lastname: Lee
authors.forename: C-W
authors.initials: CW
authors.lastname: Goh
authors.forename: J-K
authors.initials: JK
authors.lastname: Oh
authors.forename: H-S
authors.initials: HS
authors.lastname: Nam
authors.forename: Y
authors.initials: Y
authors.lastname: Park
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000378:metabolism; D002097:C-Reactive Protein / Q000378:metabolism; D003402:Creatine Kinase / Q000378:metabolism; D015444:Exercise / Q000502:physiology*; D005080:Exercise Test; D006801:Humans; D006973:Hypertension / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D020097:Natriuretic Peptide, Brain / Q000378:metabolism; D010446:Peptide Fragments / Q000378:metabolism; D010807:Physical Endurance / Q000502:physiology*; D012420:Running / Q000502:physiology*
chemical_list: D015415:Biomarkers; D010446:Peptide Fragments; C109794:pro-brain natriuretic peptide (1-76); D020097:Natriuretic Peptide, Brain; D002097:C-Reactive Protein; D003402:Creatine Kinase