title: Is blood ammonia influenced by kidney function? A prospective study.
abstract: BACKGROUND
  We have investigated whether blood ammonia is increased with worsening CKD.
  
  
  METHODS
  Fifty eight subjects with a range of CKD were recruited for analysis of plasma ammonia and other electrolytes.
  
  
  RESULTS
  The concentrations of plasma ammonia were all within the normal reference range and there was no correlation between ammonia and CKD without any effect of dialysis.
  
  
  CONCLUSIONS
  Blood ammonia is not elevated in or related to the severity of chronic kidney disease.
authors.affiliation: Department of Nephrology, Royal Liverpool and Broadgreen University Hospital NHS Trust, Liverpool, UK.
authors.forename: Muhammad
authors.initials: M
authors.lastname: Imran
authors.forename: Yaser
authors.initials: Y
authors.lastname: Shah
authors.forename: Seema
authors.initials: S
authors.lastname: Nundlall
authors.forename: Norman B
authors.initials: NB
authors.lastname: Roberts
authors.forename: Matthew
authors.initials: M
authors.lastname: Howse
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000641:Ammonia / Q000097:blood*; D001639:Bicarbonates / Q000097:blood; D003404:Creatinine / Q000097:blood; D005919:Glomerular Filtration Rate; D006801:Humans; D007668:Kidney / Q000503:physiopathology*; D008875:Middle Aged; D011446:Prospective Studies; D006435:Renal Dialysis; D051436:Renal Insufficiency, Chronic / Q000097:blood* / Q000503:physiopathology* / Q000628:therapy; D012720:Severity of Illness Index; D014508:Urea / Q000097:blood; D014511:Uremia / Q000097:blood / Q000503:physiopathology / Q000628:therapy; D055815:Young Adult
chemical_list: D001639:Bicarbonates; D000641:Ammonia; D014508:Urea; D003404:Creatinine