title: A portable instrument for high-speed brain function imaging: FEITER.
abstract: Electrical Impedance Tomography (EIT) can resolve dynamic physiological information deep within human subjects [1], but its sensitivity is challenged in the case of imaging the head [2]. Here, we report a new system called fEITER that has been designed and built to enable functional imaging of the human brain using EIT via scalp-mounted electrodes, integrated with stimulation of evoked responses. Using Field-Programmable Gate Array (FPGA) technology, it provides excellent flexibility in terms of current-pattern excitation and signal processing. The instrument operates at 100 frames/second (fps) with noise of 1 μV on the rms voltage measurements. Clinical trials have been authorized by the UK MHRA and example data from human subjects are presented.
authors.affiliation: School of Electrical and Electronic Engineering, University of Manchester, Manchester, UK. h.mccann@manchester.ac.uk
authors.forename: Hugh
authors.initials: H
authors.lastname: McCann
authors.forename: S Talha
authors.initials: ST
authors.lastname: Ahsan
authors.forename: John L
authors.initials: JL
authors.lastname: Davidson
authors.forename: Rebecca L
authors.initials: RL
authors.lastname: Robinson
authors.forename: Paul
authors.initials: P
authors.lastname: Wright
authors.forename: Chris J D
authors.initials: CJ
authors.lastname: Pomfrett
mesh_terms: D001921:Brain / Q000473:pathology; D001931:Brain Mapping / Q000379:methods; D003201:Computers; D004553:Electric Conductivity; D017097:Electric Impedance; D004562:Electrocardiography / Q000379:methods*; D004566:Electrodes; D004594:Electrophysiology / Q000379:methods*; D004867:Equipment Design; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods; D021621:Imaging, Three-Dimensional / Q000379:methods; D019047:Phantoms, Imaging; D015203:Reproducibility of Results; D012535:Scalp / Q000473:pathology; D059629:Signal-To-Noise Ratio; D013997:Time Factors; D014054:Tomography / Q000379:methods*