title: Direct chemoselective allylation of inert amide carbonyls.
abstract: Direct allylation of inert amide carbonyls utilizing the Schwartz reagent afforded either substituted tertiary or secondary amines. A preactivation step was successfully avoided, which is generally a requisite to increase the electrophilicity of amides. The reaction exhibited remarkable functional group tolerance and proceeded even in the presence of methyl esters and nitro groups.
authors.affiliation: Department of Applied Chemistry, Faculty of Science and Technology, Keio University, 3-14-1, Hiyoshi, Yokohama 223-8522, Japan.
authors.forename: Yukiko
authors.initials: Y
authors.lastname: Oda
authors.forename: Takaaki
authors.initials: T
authors.lastname: Sato
authors.forename: Noritaka
authors.initials: N
authors.lastname: Chida
mesh_terms: D000498:Allyl Compounds / Q000737:chemistry*; D000577:Amides / Q000737:chemistry*; D015394:Molecular Structure
chemical_list: D000498:Allyl Compounds; D000577:Amides