title: Continuous-flow hydration-condensation reaction: Synthesis of α,β-unsaturated ketones from alkynes and aldehydes by using a heterogeneous solid acid catalyst.
abstract: A simple, practical and efficient continuous-flow hydration-condensation protocol was developed for the synthesis of α,β-unsaturated ketones starting from alkynes and aldehydes by employing a heterogeneous catalyst in a flow microwave. The procedure presents a straightforward and convenient access to valuable differently substituted chalcones and can be applied on multigram scale.
authors.affiliation: Institute of Organic Chemistry, RWTH Aachen University, Landoltweg 1, D-52074 Aachen, Germany.
authors.forename: Magnus
authors.initials: M
authors.lastname: Rueping
authors.forename: Teerawut
authors.initials: T
authors.lastname: Bootwicha
authors.forename: Hannah
authors.initials: H
authors.lastname: Baars
authors.forename: Erli
authors.initials: E
authors.lastname: Sugiono