title: Predicting phosphene elicitation in patients with retinal implants: a mathematical study.
abstract: Single pulse waveforms were considered in a recent model for phosphene elicitation in patients with a retinal prosthesis. Waveforms are constrained to charge-balanced stimuli consisting of a single cathodic and anodic pulse pair. Mathematical models of such stimuli have been constructed and presented based upon patient testimonials. In this work, we derive analytic expressions that may be employed to determine equibrightness levels for different waveforms. We provide an example calculation to show quantitative improvements in stimulation efficiency that are consistent with qualitative findings on waveform effects.
authors.affiliation: Department of Electrical and Electronic Engineering, The University of Melbourne. cosavage@unimelb.edu.au
authors.forename: Craig O
authors.initials: CO
authors.lastname: Savage
authors.forename: David B
authors.initials: DB
authors.lastname: Grayden
authors.forename: Hamish
authors.initials: H
authors.lastname: Meffin
authors.forename: Anthony N
authors.initials: AN
authors.lastname: Burkitt
mesh_terms: D000465:Algorithms; D004558:Electric Stimulation / Q000379:methods; D004566:Electrodes; D004594:Electrophysiology; D006801:Humans; D008027:Light; D015233:Models, Statistical; D008962:Models, Theoretical; D017711:Nonlinear Dynamics; D010719:Phosphenes; D019736:Prostheses and Implants; D012160:Retina / Q000473:pathology*; D012162:Retinal Degeneration / Q000628:therapy*; D014785:Vision, Ocular