title: Pyrazinamide: a frontline drug used for tuberculosis. Molecular mechanism of action resolved after 50 years?
authors.affiliation: Center for Drug Design, Academic Health Center, University of Minnesota, 7-215 Phillips Wangensteen Building, Minneapolis, MN 55455, USA.
authors.forename: Alvin S
authors.initials: AS
authors.lastname: Kalinda
authors.forename: Courtney C
authors.initials: CC
authors.lastname: Aldrich
mesh_terms: D000581:Amidohydrolases / Q000378:metabolism; D000995:Antitubercular Agents / Q000494:pharmacology*; D006801:Humans; D009169:Mycobacterium tuberculosis / Q000187:drug effects* / Q000235:genetics; D011718:Pyrazinamide / Q000378:metabolism / Q000494:pharmacology*; D014376:Tuberculosis / Q000188:drug therapy / Q000382:microbiology
chemical_list: D000995:Antitubercular Agents; D011718:Pyrazinamide; D000581:Amidohydrolases; C487496:PncA protein, Mycobacterium tuberculosis