title: Locating of the required key-variables to be employed in a ventilation management decision support system.
abstract: The aim of the paper is to identify the key physiological variables and ventilator settings involved in ventilation management, and required for an appropriate Clinical Decision Support System (CDSS). Based on the results of a questionnaire designed for the purpose of the research, 70 hours of physiological and ventilation data were recorded. Recorded data were classified by clinicians into three major lung pathologies and were further statistically analyzed for identifying strong relationships between monitored and controlled ventilator parameters. Correlation analysis was evaluated by Intensive Care Unit (ICU) clinicians. Based on the evaluators' majority voting the number and type of participating variables in a CDSS was drastically decreased. The number and type of monitored variables ranged from a single one to six, depending on the patient's lung pathology, and the controlled ventilator setting. Evaluation results were successfully applied to Neural Network models for providing suggestions on Tidal Volume and the Fraction of inspired Oxygen.
authors.affiliation: Medical Instrumentation Technology Department, Technological Educational Institute of Athens, Greece. atzavaras@teiath.gr
authors.forename: A
authors.initials: A
authors.lastname: Tzavaras
authors.forename: P R
authors.initials: PR
authors.lastname: Weller
authors.forename: G
authors.initials: G
authors.lastname: Prinianakis
authors.forename: A
authors.initials: A
authors.lastname: Lahana
authors.forename: P
authors.initials: P
authors.lastname: Afentoulidis
authors.forename: B
authors.initials: B
authors.lastname: Spyropoulos
mesh_terms: D003627:Data Interpretation, Statistical; D020000:Decision Support Systems, Clinical; D003936:Diagnosis, Computer-Assisted / Q000379:methods*; D006801:Humans; D016571:Neural Networks, Computer; D010363:Pattern Recognition, Automated / Q000379:methods*; D029424:Pulmonary Disease, Chronic Obstructive / Q000534:rehabilitation*; D012121:Respiration, Artificial