title: An adult patient with acute infection with hepatitis B virus genotype C that progressed to chronic infection.
abstract: In 2008, a 28-year-old woman consulted our hospital due to general fatigue. Her ALT level was within normal range but she was positive for hepatitis B surface antigen (HBsAg). Her ALT level was nearly within normal range thereafter and she was consistently positive for HBeAg. Later, it was proven that she was negative for HBsAg in 1999. She had been a sex worker in 2007-2008. Complete genome sequencing revealed that her HBV was genotype C. The present case may indicate that it is possible for acute infection with HBV genotype C to progress to chronic infection in adults.
authors.affiliation: Gastroenterology Center, Ehime Prefectural Central Hospital, Japan.
authors.forename: Toru
authors.initials: T
authors.lastname: Miyoshi
authors.forename: Atsushi
authors.initials: A
authors.lastname: Hiraoka
authors.forename: Satoshi
authors.initials: S
authors.lastname: Hidaka
authors.forename: Yuko
authors.initials: Y
authors.lastname: Shimizu
authors.forename: Keiko
authors.initials: K
authors.lastname: Ninomiya
authors.forename: Hiroki
authors.initials: H
authors.lastname: Utsunomiya
authors.forename: Nayu
authors.initials: N
authors.lastname: Tazuya
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Tanihira
authors.forename: Aki
authors.initials: A
authors.lastname: Hasebe
authors.forename: Yasunao
authors.initials: Y
authors.lastname: Miyamoto
authors.forename: Tomoyuki
authors.initials: T
authors.lastname: Ninomiya
authors.forename: Masanori
authors.initials: M
authors.lastname: Abe
authors.forename: Yoichi
authors.initials: Y
authors.lastname: Hiasa
authors.forename: Morikazu
authors.initials: M
authors.lastname: Onji
authors.forename: Kojiro
authors.initials: K
authors.lastname: Michitaka
mesh_terms: D000328:Adult; D005260:Female; D005838:Genotype; D006515:Hepatitis B virus / Q000235:genetics*; D019694:Hepatitis B, Chronic / Q000175:diagnosis* / Q000235:genetics*; D006801:Humans; D010802:Phylogeny; D060386:Sex Workers