title: [Triterpenes and sterols from Nauclea latifolia].
abstract: OBJECTIVE
  To investigate the chemical constituents of Nauclea latifolia, which is an African folk medicine and collected from Guinea.
  
  
  METHODS
  The chemical constituents were isolated by silica gel and Sephadex LH-20 column chromatographies, and structurally elucidated by spectral evidence together with physiochemical properties.
  
  
  RESULTS
  Twelve compounds including 8 triterpenes and 4 sterols were isolated from the roots of N. latifolia, and their structures were defined as 24-en-cycloartenone (1), ursolic aldehyde (2), quinovic acid (3), rotundic acid (4), 3beta,19alpha,23,24-tetrahydroxyurs-12-en-28-oic acid (5), pyrocincholic acid 3beta-O-beta-D-fucopyranoside (6), quinovic acid 3beta-O-beta-D-glucopyranoside (7), quinovic acid-3b-O-D-glucopyranosyl-(28-->1)-beta-D-glucopyranosyl ester (8), beta-sitosterol (9), stigmastan-3,6-dione (10), stigmast-4-en-6beta-ol-3-one (11) and daucosterol (12) .
  
  
  CONCLUSIONS
  All compounds except for 4,9, andl2 are isolated from this plant for the fist time, while compounds 2, 6, 10, and 11 are isolated from the genus Nauclea for the first time.
authors.affiliation: Key Laboratory of Modern Chinese Medicines, China Pharmaceutical University, Ministry of Education, Research Department of Pharmacognosy, China Pharmaceutical University, Nanjing 211198, China.
authors.forename: Ling
authors.initials: L
authors.lastname: Wang
authors.forename: Chaofeng
authors.initials: C
authors.lastname: Zhang
authors.forename: Mara
authors.initials: M
authors.lastname: Layba
authors.forename: Mian
authors.initials: M
authors.lastname: Zhang
mesh_terms: D002845:Chromatography / Q000379:methods; D016701:Guinea; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification; D018517:Plant Roots / Q000737:chemistry* / Q000378:metabolism; D010946:Plants, Medicinal / Q000737:chemistry; D019666:Rubiaceae / Q000737:chemistry* / Q000378:metabolism; D013261:Sterols / Q000737:chemistry* / Q000302:isolation & purification*; D014315:Triterpenes / Q000737:chemistry* / Q000302:isolation & purification*
chemical_list: D010936:Plant Extracts; D013261:Sterols; D014315:Triterpenes