title: Classes of depression, anxiety, and functioning in acute coronary syndrome patients.
abstract: OBJECTIVE
  To describe change in subgroups characterized by patterns of depression, anxiety, and functional impairment; examine treatment effects on subgroup membership; examine effects of sex and age on subgroup membership.
  
  
  METHODS
  Latent class models were used to meet  the first 2 objectives using 79 patients with depression/anxiety. Generalized estimating equations were used to meet the third objective.
  
  
  RESULTS
  Three subgroups characterized by different combinations of psychiatric disorders and functioning were identified. Patients who received  treatment were more likely to transition to a less impaired subgroup.
  
  
  CONCLUSIONS
  Unique information about holistic treatment effects can be gained when multiple outcomes are considered simultaneously.
authors.affiliation: Dissemination and Implementation Unit, Center for Health Policy and Research, University of Massachusetts School ofMedicine, Worcester MA, USA. mayratismi@gmail.com
authors.forename: Mayra
authors.initials: M
authors.lastname: Tisminetzky
authors.forename: Bethany C
authors.initials: BC
authors.lastname: Bray
authors.forename: Ruben
authors.initials: R
authors.lastname: Miozzo
authors.forename: Onesky
authors.initials: O
authors.lastname: Aupont
authors.forename: Thomas
authors.initials: T
authors.lastname: McLaughlin
mesh_terms: D054058:Acute Coronary Syndrome / Q000150:complications / Q000523:psychology* / Q000628:therapy*; D000223:Adaptation, Psychological; D000367:Age Factors; D001007:Anxiety / Q000150:complications / Q000175:diagnosis*; D015928:Cognitive Behavioral Therapy / Q000379:methods / Q000706:statistics & numerical data*; D003863:Depression / Q000150:complications / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008960:Models, Psychological; D011569:Psychiatric Status Rating Scales / Q000706:statistics & numerical data; D012737:Sex Factors