title: Electrical detachment of cells for engineering capillary-like structures in a photocrosslinkable hydrogel.
abstract: A major challenge in tissue engineering is the fabrication of vascular networks capable of delivering oxygen and nutrients throughout tissue constructs. Because cells located more than a few hundred micrometers away from the nearest capillaries are susceptible to oxygen shortages, it is crucial to develop microscale technologies for engineering a vascular structure in three-dimensionally thick tissues. This study describes an electrochemical approach for fabricating capillary-like structures precisely aligned within micrometer distances, the internal surfaces of which are covered with vascular endothelial cells in a photocrosslinkable hydrogel.
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Osaki
authors.forename: Takahiro
authors.initials: T
authors.lastname: Kakegawa
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Suzuki
authors.forename: Junji
authors.initials: J
authors.lastname: Fukuda
mesh_terms: D000595:Amino Acid Sequence; D002448:Cell Adhesion; D006801:Humans; D020100:Hydrogels; D008969:Molecular Sequence Data; D009842:Oligopeptides / Q000737:chemistry; D010777:Photochemistry; D023822:Tissue Engineering
chemical_list: D020100:Hydrogels; D009842:Oligopeptides