title: Myoglobin-associated acute kidney injury in the setting of ciprofloxacin administration.
abstract: Myoglobin-associated kidney injury typically is seen in severe rhabdomyolysis. Nontraumatic rhabdomyolysis may be triggered by direct drug toxicity, drug-drug interactions, and individual patient myopathic risk factors. We present a case of myoglobin-associated kidney failure in the setting of repeated ciprofloxacin administration in a lung transplant patient. Kidney biopsy was critical to establishing the diagnosis and avoiding future exposure.
authors.affiliation: Department of Medicine, Division of Nephrology and Hypertension, Mayo Clinic College of Medicine, Rochester, MN 55905, USA. qian.qi@mayo.edu
authors.forename: Qi
authors.initials: Q
authors.lastname: Qian
authors.forename: Samih H
authors.initials: SH
authors.lastname: Nasr
authors.forename: Clement O
authors.initials: CO
authors.lastname: Akogyeram
authors.forename: Sanjeev
authors.initials: S
authors.lastname: Sethi
mesh_terms: D058186:Acute Kidney Injury / Q000139:chemically induced*; D000890:Anti-Infective Agents / Q000009:adverse effects*; D002939:Ciprofloxacin / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009211:Myoglobin
chemical_list: D000890:Anti-Infective Agents; D009211:Myoglobin; D002939:Ciprofloxacin