title: A small IncQ-type plasmid carrying the quinolone resistance (qnrS2) gene from Aeromonas hydrophila.
abstract: OBJECTIVE
  To investigate the qnrS2 gene encoded by a plasmid obtained from Aeromonas hydrophila.
  
  
  RESULTS
  To investigate the full-length sequence of the plasmid carrying qnrS2 (plasmid designated pAHH04) from the strain SNUFPC-A10, the full-length coding sequence of the qnrS region was first amplified. The remaining part of the plasmid was read outwards from this region. The plasmid pAHH04 contained the repC, repA, mobA and mobC genes, and its total size was 7191 bp with a G+C content of 60%.
  
  
  CONCLUSIONS
  This study describes the full-length sequence of a plasmid carrying the qnrS2 gene from Aer. hydrophila. The plasmid pAHH04 carried plasmid replication and mobilization genes from IncQ-type plasmids.
  
  
  CONCLUSIONS
  The isolated qnrS2 gene encoded by a plasmid from an Aer. hydrophila strain is of significant importance because it emphasizes the problem of antibiotic resistance as well as the ability of the determinants to spread among the different bacterial species that impact human health.
authors.affiliation: Laboratory of Aquatic Animal Medicine, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, Seoul, Korea.
authors.forename: J E
authors.initials: JE
authors.lastname: Han
authors.forename: J H
authors.initials: JH
authors.lastname: Kim
authors.forename: C H
authors.initials: CH
authors.lastname: Choresca
authors.forename: S P
authors.initials: SP
authors.lastname: Shin
authors.forename: J W
authors.initials: JW
authors.lastname: Jun
authors.forename: J Y
authors.initials: JY
authors.lastname: Chai
authors.forename: S C
authors.initials: SC
authors.lastname: Park
mesh_terms: D016980:Aeromonas hydrophila / Q000235:genetics*; D004261:DNA Replication; D024881:Drug Resistance, Bacterial; D006801:Humans; D008969:Molecular Sequence Data; D010957:Plasmids; D015363:Quinolones / Q000494:pharmacology; D017422:Sequence Analysis, DNA
chemical_list: D015363:Quinolones