title: [Identification of chemical constituents in qiliqiangxin capsule by UPLC-Q-TOF/MS(E)].
abstract: In order to clarify the chemical constituents in Qiliqiangxin capsule, a rapid ultra-performance liquid chromatography/orthogonal acceleration time-of-flight mass spectrometry (UPLC-Q-TOF/MS(E)) method was established. Forty peaks were identified on line using this method. The herbal sources of these peaks were assigned. The results implied that triterpenoid saponins, flavonoid glycosides, C21-steroids and phenolic acids were included in the main components of Qiliqiangxin capsule. The method is simple and rapid for elucidation of the constituents of Qiliqiangxin capsule and the results are useful for the quality control of Qiliqiangxin capsule.
authors.affiliation: Beijing Institute of Radiation Medicine, Academy of Military Medical Sciences, Beijing 100850, China.
authors.forename: Li-ping
authors.initials: LP
authors.lastname: Kang
authors.forename: Yang
authors.initials: Y
authors.lastname: Zhao
authors.forename: He-shui
authors.initials: HS
authors.lastname: Yu
authors.forename: Yi-xun
authors.initials: YX
authors.lastname: Liu
authors.forename: Cheng-qi
authors.initials: CQ
authors.lastname: Xiong
authors.forename: Da-wei
authors.initials: DW
authors.lastname: Tan
authors.forename: Ji-ming
authors.initials: JM
authors.lastname: Jia
authors.forename: Hong-tao
authors.initials: HT
authors.lastname: Wang
authors.forename: Shu-yan
authors.initials: SY
authors.lastname: Tian
authors.forename: Bai-Ping
authors.initials: BP
authors.lastname: Ma
mesh_terms: D002214:Capsules; D002851:Chromatography, High Pressure Liquid; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D047309:Flavones / Q000032:analysis; D036145:Ginsenosides / Q000032:analysis; D006027:Glycosides / Q000032:analysis; D062385:Hydroxybenzoates / Q000032:analysis; D010946:Plants, Medicinal / Q000737:chemistry; D011786:Quality Control; D012503:Saponins / Q000032:analysis*; D021241:Spectrometry, Mass, Electrospray Ionization; D013256:Steroids / Q000032:analysis; D053719:Tandem Mass Spectrometry; D014315:Triterpenes / Q000032:analysis*
chemical_list: D002214:Capsules; D004365:Drugs, Chinese Herbal; D047309:Flavones; D036145:Ginsenosides; D006027:Glycosides; D062385:Hydroxybenzoates; D012503:Saponins; D013256:Steroids; D014315:Triterpenes; C560534:astragaloside VII; C572413:qiliqiangxin; C017616:phenolic acid