title: Captured at last: a catalyst-substrate adduct and a Rh-dihydride solvate in the asymmetric hydrogenation by a Rh-monophosphine catalyst.
abstract: The mechanism of asymmetric hydrogenation catalyzed by [Rh(NBD)((R)-PhenylBinepine)(2)]SbF(6)1 has been studied by NMR experiments and DFT computations. Either the low-temperature hydrogenation of the catalyst-substrate adduct 4 or the reaction of solvate dihydride 6 with MAC produced the hydrogenation product with over 99% ee (S).
authors.affiliation: Department of Applied Chemistry, Graduate School of Science and Engineering, Tokyo Institute of Technology 2-12-1 O-okayama, Tokyo 152-8552, Japan. gridnev.i.aa@m.titech.ac.jp
authors.forename: Ilya D
authors.initials: ID
authors.lastname: Gridnev
authors.forename: Elisabetta
authors.initials: E
authors.lastname: Alberico
authors.forename: Serafino
authors.initials: S
authors.lastname: Gladiali
mesh_terms: D002384:Catalysis; D006865:Hydrogenation; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D009942:Organometallic Compounds / Q000737:chemistry*; D010720:Phosphines / Q000737:chemistry*; D012238:Rhodium / Q000737:chemistry*
chemical_list: D009942:Organometallic Compounds; D010720:Phosphines; D012238:Rhodium; C044646:phosphine