title: "Studying the cutaneous microcirculatory response during upper-limb exercise in healthy, older, sedentary people".
abstract: This study investigated changes incurred in cutaneous skin blood flux (SKBF) in the superficial veins of the lower limb by upper limb exercise training in the form of arm-cranking in 14 healthy participants over the age of 50 years. Changes in cutaneous microvascular function of the lower leg were assessed using laser Doppler Flowmetry (LDF) during a 30-minute exercise session undertaken over 4-exercise periods. Both SKBF and Time to reach Peak Perfusion (Tmax) were improved significantly during the 2nd (e.g. 121 (± 107.2) vs 280 (± 269.1) and 171 (± 34.4) vs. 247 (± 38.3) respectively) when compared to the first exercise period, while values approaching initial levels in the following stages. The results indicate that the thermoregulatory and vasodilation mechanisms observed during exercise in middle-aged and older healthy people are different to the one appearing in younger age groups, suggesting a more extensive effect of the age-related structural changes than it was previously thought.
authors.affiliation: Centre for Sport and Exercise Science, Sheffield Hallam University, Sheffield, UK. klonizakis@gmail.com
authors.forename: Markos
authors.initials: M
authors.lastname: Klonizakis
mesh_terms: D000368:Aged; D001132:Arm / Q000502:physiology*; D001783:Blood Flow Velocity; D015444:Exercise / Q000502:physiology*; D005260:Female; D006801:Humans; D017078:Laser-Doppler Flowmetry; D007866:Leg / Q000098:blood supply*; D008297:Male; D008833:Microcirculation / Q000502:physiology*; D008875:Middle Aged; D012867:Skin / Q000098:blood supply*; D012879:Skin Physiological Phenomena; D012881:Skin Temperature; D014664:Vasodilation / Q000502:physiology