title: Synthesis of acyl pyrroles via palladium-catalyzed carbonylative amination of aryl and alkenyl iodides.
abstract: A palladium-catalyzed synthesis of acyl pyrroles from aryl and alkenyl iodides is reported. This carbonylative amination requires only atmospheric (balloon) pressure of carbon monoxide and proceeds with Pd(PPh(3))(4) and Pd-NHC catalysts. Aryl and heteroaryl iodides give the corresponding acyl pyrroles in good to excellent yields, while alkenyl iodides provide the corresponding acyl pyrroles in low to moderate yields.
authors.affiliation: Department of Chemistry, York University, 440 Chemistry Building 4700 Keele Street, Toronto, ON, Canada M3J 1P3.
authors.forename: Stephanie
authors.initials: S
authors.lastname: Ho
authors.forename: Ganna
authors.initials: G
authors.lastname: Bondarenko
authors.forename: David
authors.initials: D
authors.lastname: Rosa
authors.forename: Bojan
authors.initials: B
authors.lastname: Dragisic
authors.forename: Arturo
authors.initials: A
authors.lastname: Orellana