title: Bone level change of extraction sockets with Bio-Oss collagen and implant placement: a clinical study.
abstract: OBJECTIVE
  To compare the reaction of the alveolar bone to the preservation of the extraction socket by Bio-Oss Collagen with and without combination of implant treatment. To evaluate whether early implant insertion 8-10weeks thereafter could be a suitable time point for long term bone stability around the implant.
  
  
  METHODS
  A total of 25 patients were divided into three groups: The first group (seven patients) received Bio-Oss Collagen after extraction and 8-10weeks later an implant, the second group (eight patients) received only Bio-Oss Collagen without implantation thereafter, while the third group was considered as a control (eleven patients), where the sockets healed without any treatment. The change in the vertical bone level of the alveolar crests were measured from panoramic radiographs and statistically analysed.
  
  
  RESULTS
  Bone level change was significantly less for Group 1 than Group 3 (P<0.001), while was not significantly different for Group 2 and Group 3 (P=0.23). However, the rate of bone level change per year was statistically smaller for Group 1 compared to Group 3 (P=0.019) and as well as for Group 1 than for Group 2 (P=0.003), whereas the change per year was not significantly different for Group 2 vs. Group 3 (P=0.122).
  
  
  CONCLUSIONS
  Bone level preservation of extraction sockets using Bio-Oss Collagen with implantation is significantly better compared to using Bio-Oss Collagen only and untreated sockets. Implant insertion 8-10weeks after extraction is a suitable time point after socket augmentation.
authors.affiliation: Department of Prosthodontics, Gerodontology and Biomaterials, University of Greifswald, Rotgerberstr. 8, 17475 Greifswald, Germany. FriedhelmHeinemann@web.de
authors.forename: Friedhelm
authors.initials: F
authors.lastname: Heinemann
authors.forename: Istabrak
authors.initials: I
authors.lastname: Hasan
authors.forename: Christian
authors.initials: C
authors.lastname: Schwahn
authors.forename: Christoph
authors.initials: C
authors.lastname: Bourauel
authors.forename: Torsten
authors.initials: T
authors.lastname: Mundt
mesh_terms: D000539:Alveolar Process / Q000000981:diagnostic imaging / Q000601:surgery*; D000540:Alveolar Ridge Augmentation / Q000295:instrumentation / Q000379:methods*; D003131:Combined Modality Therapy; D019250:Dental Implants, Single-Tooth; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008903:Minerals / Q000627:therapeutic use*; D011859:Radiography; D014081:Tooth Extraction / Q000009:adverse effects* / Q000295:instrumentation / Q000379:methods*; D020390:Tooth Socket / Q000000981:diagnostic imaging / Q000601:surgery*; D016896:Treatment Outcome; D014945:Wound Healing
chemical_list: C077540:Bio-Oss; D008903:Minerals