title: Magnetic resonance enterography guiding treatment in children with Crohn's jejunoileitis.
abstract: OBJECTIVE
  To determine the usefulness of magnetic resonance enterography (MRE) in treatment for paediatric patients with Crohn's disease.
  
  
  METHODS
  To evaluate small bowel involvement, 45 children with Crohn's disease were scheduled for MRE. Two radiologists blinded to the patient data independently re-evaluated the images. Findings in images were compared to macroscopic findings at surgery or endoscopy.
  
  
  RESULTS
  The terminal ileum was visualized in all with a completed procedure (43/45). The treatment remained conservative in 74% after imaging. In all 13 patients who underwent ileocolonoscopy within 3 months of MRE, the MRE findings were comparable with the macroscopic findings or revealed a more extensive disease. Bowel resection was performed in 26% after imaging. The macroscopic findings in the bowel corresponded to the MRE findings in 73%. In three MRE suggested a more severe disease than was verified intraoperatively.
  
  
  CONCLUSIONS
  Magnetic resonance enterography identifies disease involvement in the small bowel in young patients with Crohn's disease and may guide decisions on the need for intestinal surgery or adjustment of medication.
authors.affiliation: Children's Hospital, University of Helsinki, Finland. maija.piekkala@helsinki.fi
authors.forename: M
authors.initials: M
authors.lastname: Piekkala
authors.forename: T
authors.initials: T
authors.lastname: Kalajoki-Helmiö
authors.forename: L
authors.initials: L
authors.lastname: Martelius
authors.forename: M
authors.initials: M
authors.lastname: Pakarinen
authors.forename: R
authors.initials: R
authors.lastname: Rintala
authors.forename: K-L
authors.initials: KL
authors.lastname: Kolho
mesh_terms: D000293:Adolescent; D002648:Child; D003113:Colonoscopy; D003424:Crohn Disease / Q000175:diagnosis* / Q000628:therapy*; D004751:Enteritis / Q000175:diagnosis / Q000628:therapy; D005260:Female; D006801:Humans; D007079:Ileitis / Q000175:diagnosis / Q000628:therapy; D007579:Jejunal Diseases / Q000175:diagnosis / Q000628:therapy; D008279:Magnetic Resonance Imaging; D008297:Male