title: Monitoring healthy metabolic trajectories with nutritional metabonomics.
abstract: Metabonomics is a well established analytical approach for the analysis of physiological regulatory processes via the metabolic profiling of biofluids and tissues in living organisms. Its potential is fully exploited in the field of "nutrimetabonomics" that aims at assessing the metabolic effects of active ingredients and foods in individuals. Yet, one of the greatest challenges in nutrition research is to decipher the critical interactions between mammalian organisms and environmental factors, including the gut microbiota. "Nutrimetabonomics" is today foreseen as a powerful approach for future nutritional programs tailored at health maintenance and disease prevention.
authors.affiliation: BioAnalytical Science, Metabonomics & Biomarkers, Nestlé Research Center, PO Box 44, CH-1000 Lausanne 26, Switzerland. Sebastiano.Collino@rdls.nestle.com
authors.forename: Sebastiano
authors.initials: S
authors.lastname: Collino
authors.forename: François-Pierre J
authors.initials: FP
authors.lastname: Martin
authors.forename: Sunil
authors.initials: S
authors.lastname: Kochhar
authors.forename: Serge
authors.initials: S
authors.lastname: Rezzi
mesh_terms: D005504:Food Analysis / Q000379:methods*; D041981:Gastrointestinal Tract / Q000382:microbiology*; D006801:Humans; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D013058:Mass Spectrometry / Q000379:methods; D055442:Metabolome; D055432:Metabolomics / Q000379:methods*; D054892:Metagenome; D009747:Nutritional Physiological Phenomena / Q000502:physiology*