title: [Endocarditis in Iceland 2000-2009, a national survey incidence, microbiology and prognosis].
abstract: The objective of this study was to analyze the incidence, clinical features, microbiology and prognosis of patients with infective endocarditis (IE) in Iceland, and to compare the results with a previous study made in Iceland 1976-85.
  
  
  
  A retrospective study including all patients diagnosed with IE in Iceland 2000-2009. Information was obtained from medical records.
  
  
  
  A total of 88 cases (71% men, mean age 59 years) were diagnosed and the incidence of IE was calculated 2.97/100.000 person-years. The mitral valve was infected in 35 patients (40%), aortic in 27 (31%) and tricuspid in 9 (10%). In 19 cases a prosthetic valve was infected (22%), one early (<<60 days from procedure) and 18 late. Sixteen patients were intravenous drug users. The most common causative organisms were streptococcus (33%), staphylococcus (25%) and enterococcus (16%). Surgical intervention was performed in 16 cases (18%). One and five year survival was 77% and 57% respectively.
  
  
  
  The incidence of IE in Iceland is still low compared to other countries. The clinical profile of the disease has changed since 1976-85, patients with prosthetic heart valves and intravenous drug users were more prominent than before. The microbiological spectrum has not changed much, streptococcus is still the most common pathogen, contrary to what is seen in other industrial countries where S. aureus is more frequent. Death rate is lower than before and one year survival good compared to other reports.
authors.affiliation: Faculty of Medicine, Reykjavik, Iceland. ebt1@hi.is
authors.forename: Elin Björk
authors.initials: EB
authors.lastname: Tryggvadóttir
authors.forename: Uggi Thordur
authors.initials: UT
authors.lastname: Agnarsson
authors.forename: Jón Thor
authors.initials: JT
authors.lastname: Sverrisson
authors.forename: Sigurdur B
authors.initials: SB
authors.lastname: Thorsteinsson
authors.forename: Jön Vilberg
authors.initials: JV
authors.lastname: Högnason
authors.forename: Gudmundur
authors.initials: G
authors.lastname: Thorgeirsson
mesh_terms: D004697:Endocarditis, Bacterial / Q000175:diagnosis / Q000453:epidemiology* / Q000382:microbiology / Q000401:mortality / Q000628:therapy; D004756:Enterobacteriaceae Infections / Q000175:diagnosis / Q000453:epidemiology* / Q000382:microbiology / Q000401:mortality / Q000628:therapy; D005260:Female; D006306:Health Surveys; D006350:Heart Valve Prosthesis / Q000382:microbiology; D006801:Humans; D007055:Iceland / Q000453:epidemiology; D015994:Incidence; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D016459:Prosthesis-Related Infections / Q000175:diagnosis / Q000453:epidemiology* / Q000382:microbiology / Q000401:mortality / Q000628:therapy; D012189:Retrospective Studies; D018570:Risk Assessment; D012307:Risk Factors; D013203:Staphylococcal Infections / Q000175:diagnosis / Q000453:epidemiology* / Q000382:microbiology / Q000401:mortality / Q000628:therapy; D013290:Streptococcal Infections / Q000175:diagnosis / Q000453:epidemiology* / Q000382:microbiology / Q000401:mortality / Q000628:therapy; D015819:Substance Abuse, Intravenous / Q000453:epidemiology; D016019:Survival Analysis; D015996:Survival Rate; D013997:Time Factors