title: Carcinoma ex pleomorphic adenoma of the sublingual gland: a case report.
abstract: We report a case of carcinoma ex pleomorphic adenoma of a sublingual gland in a 70-year-old man. Under a clinical diagnosis of benign salivary gland tumor, excision of the mass with the sublingual salivary gland in an en bloc fashion via an intraoral approach was performed. Histopathologically, there was a rupture of the fibrous capsule and diffuse cell-rich sheets composed of myoepithelial cells with round nuclei were also seen. Immunohistochemically, the cells that composed of cell rich sheets were positive to smooth muscle actin. Final diagnosis of myoepithelial carcinoma ex pleomorphic adenoma was made.
authors.affiliation: Department of Dentistry and Oral Surgery, Osaka Medical College, Takatsuki, Japan. ora009@poh.osaka-med.ac.jp
authors.forename: Yasunori
authors.initials: Y
authors.lastname: Ariyoshi
authors.forename: Masashi
authors.initials: M
authors.lastname: Shimahara
authors.forename: Toshiyuki
authors.initials: T
authors.lastname: Konda
authors.forename: Motomu
authors.initials: M
authors.lastname: Tsuji
mesh_terms: D008949:Adenoma, Pleomorphic / Q000473:pathology*; D000368:Aged; D002277:Carcinoma / Q000737:chemistry / Q000473:pathology*; D003937:Diagnosis, Differential; D005904:Glial Fibrillary Acidic Protein / Q000032:analysis; D006801:Humans; D007633:Keratins / Q000032:analysis; D008297:Male; D009208:Myoepithelioma / Q000737:chemistry / Q000473:pathology*; D009361:Neoplasm Invasiveness; D009418:S100 Proteins / Q000032:analysis; D013362:Sublingual Gland Neoplasms / Q000737:chemistry / Q000473:pathology*
chemical_list: D005904:Glial Fibrillary Acidic Protein; D009418:S100 Proteins; D007633:Keratins