title: Centromeres poised en pointe: CDKs put a hold on CENP-A assembly.
abstract: Eukaryotic centromeres are propagated by incorporation of the centromere-specific histone CENP-A into centromeric chromatin. Silva et al. (2012) now show that cyclin-dependent kinases (CDKs) hold the CENP-A assembly machinery in an inactive state until mitotic exit and entry into G1, at which time new CENP-A is loaded.
authors.affiliation: Institute for Genome Sciences & Policy, Duke University School of Medicine, Durham, NC 27708, USA.
authors.forename: Kaitlin M
authors.initials: KM
authors.lastname: Stimpson
authors.forename: Beth A
authors.initials: BA
authors.lastname: Sullivan