title: The value of mastectomy flap fixation in reducing fluid drainage and seroma formation in breast cancer patients.
abstract: BACKGROUND
  Prolonged and excessive drainage of serous fluid and seroma formation constitute the most common complications after mastectomy for breast carcinoma. Seroma formation delays wound healing, increases susceptibility to infection, skin flap necrosis, persistent pain and prolongs convalescence. For this, several techniques have been investigated to improve primary healing and minimize seroma formation.
  
  
  METHODS
  Between June 2009 and July 2010 forty patients with breast carcinoma, scheduled for modified radical mastectomy, were randomly divided into 2 groups, the study group (20) and the control group (20). In the study group; the mastectomy flaps were fixed to the underlying muscles in raws, at various parts of the flap and at the wound edge using fine absorbable sutures. In the control group; the wound was closed in the conventional method at the edges. Closed suction drains were used in both groups. Patients, tumor characteristics and operative related factors were recorded. The amount and color of drained fluid were recorded daily. The drains were removed when the amount become less than 50 cc. The total amount and duration of drained fluid and the formation of seroma were recorded and the results were compared between the two groups.
  
  
  RESULTS
  In the flap fixation group, the drain was removed in significantly shorter time compared to the control group (p < 0.001). Also, the total amount of fluid drained was significantly lower in the flap fixation group (p < 0.001). The flap fixation group showed a significantly lower frequency of seroma formation compared to the control group, both clinically (p = 0.028) and ultrasonographically (p = 0.047).
  
  
  CONCLUSIONS
  The mastectomy flap fixation technique is a valuable procedure that significantly decreases the incidence of seroma formation, and reduces the duration and amount of drained fluid. However, it should be tried on a much wider scale to prove its validity.
authors.affiliation: Surgery department, National Cancer Institute, Cairo, Egypt. mostafasakkary@yahoo.com
authors.forename: Mostafa A
authors.initials: MA
authors.lastname: Sakkary
mesh_terms: D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000150:complications / Q000473:pathology / Q000601:surgery*; D018270:Carcinoma, Ductal, Breast / Q000150:complications / Q000473:pathology / Q000601:surgery; D018275:Carcinoma, Lobular / Q000150:complications / Q000473:pathology / Q000601:surgery; D004322:Drainage; D005122:Exudates and Transudates; D005260:Female; D006801:Humans; D015411:Mastectomy, Modified Radical; D008875:Middle Aged; D060787:Neoplasm Grading; D009367:Neoplasm Staging; D011183:Postoperative Complications; D011379:Prognosis; D011446:Prospective Studies; D049291:Seroma / Q000209:etiology* / Q000517:prevention & control*; D013524:Surgical Flaps; D013529:Surgical Wound Dehiscence / Q000209:etiology / Q000517:prevention & control*; D014945:Wound Healing