title: Surface modification of poly(styrene-b-(ethylene-co-butylene)-b-styrene) elastomer via UV-induced graft polymerization of N-vinyl pyrrolidone.
abstract: Poly(N-vinyl pyrrolidone) (PNVP) was covalently grafted onto the surface of biomedical poly(styrene-b-(ethylene-co-butylene)-b-styrene) (SEBS) elastomer via a technique of UV-induced graft polymerization combined with plasma pre-treatment. The surface graft polymerization of N-vinyl pyrrolidone (NVP) was confirmed by ATR-FTIR and XPS. Effect of the parameters of graft polymerization, i.e., the initiator concentration, the UV irradiation time and the monomer concentration on the grafting density was investigated. The morphology and the wettability of the PNVP-modified surfaces were characterized by AFM and DSA, respectively. Protein adsorption and platelet adhesion were obviously suppressed after PNVP was grafted onto the SEBS substrates.
authors.affiliation: State Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, PR China. sfluan@ciac.jl.cn
authors.forename: Shifang
authors.initials: S
authors.lastname: Luan
authors.forename: Jie
authors.initials: J
authors.lastname: Zhao
authors.forename: Huawei
authors.initials: H
authors.lastname: Yang
authors.forename: Hengchong
authors.initials: H
authors.lastname: Shi
authors.forename: Jing
authors.initials: J
authors.lastname: Jin
authors.forename: Xiaomeng
authors.initials: X
authors.lastname: Li
authors.forename: Jingchuan
authors.initials: J
authors.lastname: Liu
authors.forename: Jianwei
authors.initials: J
authors.lastname: Wang
authors.forename: Jinghua
authors.initials: J
authors.lastname: Yin
authors.forename: Paola
authors.initials: P
authors.lastname: Stagnaro
mesh_terms: D000327:Adsorption / Q000187:drug effects; D000818:Animals; D001672:Biocompatible Materials / Q000138:chemical synthesis* / Q000494:pharmacology; D001792:Blood Platelets / Q000187:drug effects; D001798:Blood Proteins / Q000737:chemistry; D020724:Elastomers / Q000138:chemical synthesis* / Q000494:pharmacology; D018625:Microscopy, Atomic Force; D010973:Platelet Adhesiveness / Q000187:drug effects; D011092:Polyethylene Glycols / Q000138:chemical synthesis* / Q000494:pharmacology; D058105:Polymerization / Q000528:radiation effects; D011137:Polystyrenes / Q000138:chemical synthesis* / Q000494:pharmacology; D011760:Pyrrolidinones / Q000737:chemistry*; D011817:Rabbits; D017550:Spectroscopy, Fourier Transform Infrared; D013499:Surface Properties / Q000187:drug effects / Q000528:radiation effects; D013816:Thermodynamics; D014466:Ultraviolet Rays
chemical_list: D001672:Biocompatible Materials; D001798:Blood Proteins; D020724:Elastomers; D011137:Polystyrenes; D011760:Pyrrolidinones; D011092:Polyethylene Glycols; C042670:N-vinyl-2-pyrrolidinone