title: Primary renal osteosarcoma with systemic dissemination.
abstract: Primary renal osteosarcoma is an uncommon disease, which, unlike its skeletal counterpart, presents mostly in adults, and is generally diagnosed late due to its non-specific features and intra-abdominal location. Even if the disease is localized at diagnosis, it follows an aggressive course despite radical surgery and adjuvant treatment. We report a case of renal osteosarcoma in a 65-year-old female, who developed regional recurrence, and lung and bone metastases soon after radical nephrectomy for localized disease. Chemotherapy was ineffective in controlling systemic disease.
authors.affiliation: Department of Radiotherapy, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Tarun
authors.initials: T
authors.lastname: Puri
authors.forename: Shikha
authors.initials: S
authors.lastname: Goyal
authors.forename: Ruchika
authors.initials: R
authors.lastname: Gupta
authors.forename: Pramod K
authors.initials: PK
authors.lastname: Julka
authors.forename: Goura K
authors.initials: GK
authors.lastname: Rath
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001706:Biopsy; D001859:Bone Neoplasms / Q000188:drug therapy / Q000556:secondary*; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000473:pathology* / Q000601:surgery; D008175:Lung Neoplasms / Q000188:drug therapy / Q000556:secondary*; D009364:Neoplasm Recurrence, Local; D009392:Nephrectomy; D012516:Osteosarcoma / Q000188:drug therapy / Q000556:secondary* / Q000601:surgery; D017211:Treatment Failure