title: Treatment of folliculitis decalvans with tacrolimus ointment.
abstract: Folliculitis decalvans is an embarrassing and challenging disease with no established treatment guidelines. In this paper, we described four patients with this disease treated successfully with Tacrolimus ointment. All of them showed significant control of the condition, stopping inflammatory lesions and progression of the disease, although weak transitory outbreaks of inflammatory lesions were observed in some cases. Alopecia and tufted hairs remained unchanged. The discontinuation of the therapy produced rapid relapses in all cases. Close monitoring of these patients is recommended due to the potential risk of malignant transformation of the disease.
authors.affiliation: Service of Dermatology, University Hospital of Gran Canaria Dr Negrín, Las Palmas de Gran Canaria, Canary Islands, Spain. jbastidai@gmail.com
authors.forename: Jesús
authors.initials: J
authors.lastname: Bastida
authors.forename: Pedro
authors.initials: P
authors.lastname: Valerón-Almazán
authors.forename: Néstor
authors.initials: N
authors.lastname: Santana-Molina
authors.forename: Carolina
authors.initials: C
authors.lastname: Medina-Gil
authors.forename: Gregorio
authors.initials: G
authors.lastname: Carretero-Hernández
mesh_terms: D000328:Adult; D005260:Female; D005499:Folliculitis / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D008297:Male; D009824:Ointments; D012536:Scalp Dermatoses / Q000188:drug therapy* / Q000473:pathology; D016559:Tacrolimus / Q000627:therapeutic use*; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D007166:Immunosuppressive Agents; D009824:Ointments; D016559:Tacrolimus