title: Organocatalytic stereoselective synthesis of passifloricin A.
abstract: The enantioselective synthesis of passifloricin A has been achieved in high diastereomeric excess. The 1,3-polyol moiety was constructed by iterative proline-catalyzed sequential α-aminoxylation and Horner-Wadsworth-Emmons (HWE) olefination of aldehydes while the synthesis of lactone moiety was achieved by ring-closing metathesis (RCM).
authors.affiliation: Division of Organic Chemistry, National Chemical Laboratory (CSIR), Pune, 411 008, India.
authors.forename: Pradeep
authors.initials: P
authors.lastname: Kumar
authors.forename: Menaka
authors.initials: M
authors.lastname: Pandey
authors.forename: Priti
authors.initials: P
authors.lastname: Gupta
authors.forename: Dilip D
authors.initials: DD
authors.lastname: Dhavale
mesh_terms: D002384:Catalysis; D015394:Molecular Structure; D011753:Pyrones / Q000138:chemical synthesis*; D013237:Stereoisomerism
chemical_list: D011753:Pyrones; C433046:passifloricin A