title: Essential oil of Myrica esculenta Buch. Ham.: composition, antimicrobial and topical anti-inflammatory activities.
abstract: Hydrodistilled oil obtained from the stem bark of Myrica esculenta Buch. Ham. ex D. Don (yield 0.3%) was analysed by capillary GC and GC-MS. The volatile oil consisted mainly of n-hexadecanol (25.2%), eudesmol acetate (21.9%), palmitic acid (11.6%), cis-β-caryophyllene (8.7%), n-pentadecanol (7.7%) and n-octadecanol (7.6%). The oil was found to be a potential antimicrobial agent against Bacillus pumilus, Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli, Pseudomonas aeruginosa, Candida albicans, Aspergillus niger and Saccharomyces cerevisiae. The essential oil exhibited significant topical anti-inflammatory activity compared to standard drug in Swiss albino mice ear.
authors.affiliation: Delhi Institute of Pharmaceutical Sciences and Research (DIPSAR), Pushp Vihar, Sec III, M.B. Road, New Delhi 110017, India. asupriya149@gmail.com
authors.forename: Supriya
authors.initials: S
authors.lastname: Agnihotri
authors.forename: Sharad
authors.initials: S
authors.lastname: Wakode
authors.forename: M
authors.initials: M
authors.lastname: Ali
mesh_terms: D000287:Administration, Topical; D000818:Animals; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology; D000890:Anti-Infective Agents / Q000737:chemistry / Q000494:pharmacology*; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology*; D001234:Aspergillus niger; D002176:Candida albicans / Q000187:drug effects; D004353:Drug Evaluation, Preclinical / Q000379:methods; D005054:Eugenol / Q000031:analogs & derivatives / Q000032:analysis; D005233:Fatty Alcohols / Q000032:analysis; D008401:Gas Chromatography-Mass Spectrometry; D051379:Mice; D031641:Myrica / Q000737:chemistry*; D009822:Oils, Volatile / Q000032:analysis / Q000737:chemistry* / Q000494:pharmacology*; D019308:Palmitic Acid / Q000032:analysis; D000081223:Polycyclic Sesquiterpenes; D011550:Pseudomonas aeruginosa / Q000187:drug effects; D012717:Sesquiterpenes / Q000032:analysis; D013211:Staphylococcus aureus / Q000187:drug effects
chemical_list: D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D005233:Fatty Alcohols; D009822:Oils, Volatile; D000081223:Polycyclic Sesquiterpenes; D012717:Sesquiterpenes; C009316:stearyl alcohol; D019308:Palmitic Acid; D005054:Eugenol; C112468:4-allyl-2,6-dimethoxyphenol; C005031:cetyl alcohol; C024714:caryophyllene