title: Synthesis of β-cyclodextrin conjugated superparamagnetic iron oxide nanoparticles for selective binding and detection of cholesterol crystals.
abstract: Water-soluble, β-cyclodextrin conjugated superparamagnetic nanoparticles have been constructed. These particles showed selective binding to cholesterol crystals, which opens the door for the detection of cholesterol crystal-related diseases such as atherosclerosis by magnetic resonance imaging (MRI).
authors.affiliation: Department of Chemistry, Michigan State University, East Lansing, Michigan 48824, USA.
authors.forename: Hongguang
authors.initials: H
authors.lastname: Li
authors.forename: Mohammad H
authors.initials: MH
authors.lastname: El-Dakdouki
authors.forename: David C
authors.initials: DC
authors.lastname: Zhu
authors.forename: George S
authors.initials: GS
authors.lastname: Abela
authors.forename: Xuefei
authors.initials: X
authors.lastname: Huang
mesh_terms: D002784:Cholesterol / Q000737:chemistry*; D003911:Dextrans / Q000138:chemical synthesis / Q000737:chemistry*; D016650:Fluorescein-5-isothiocyanate / Q000737:chemistry; D005456:Fluorescent Dyes / Q000737:chemistry; D008279:Magnetic Resonance Imaging; D058185:Magnetite Nanoparticles / Q000737:chemistry*; D053758:Nanoparticles / Q000737:chemistry*; D047392:beta-Cyclodextrins / Q000737:chemistry
chemical_list: D003911:Dextrans; D005456:Fluorescent Dyes; D058185:Magnetite Nanoparticles; D047392:beta-Cyclodextrins; D002784:Cholesterol; C065507:ferumoxides; D016650:Fluorescein-5-isothiocyanate; C031215:betadex