title: Surgical versus non-surgical interventions for treating humeral shaft fractures in adults.
abstract: BACKGROUND
  Fractures of the shaft of the humerus account for 1% to 3% of all fractures in adults. The management of these fractures, including surgical intervention, varies widely.
  
  
  OBJECTIVE
  To assess and compare the effects of surgical versus non-surgical intervention for non-pathological fractures of the humeral shaft in adults.
  
  
  METHODS
  We searched the Cochrane Bone, Joint and Muscle Trauma Group Specialised Register, the Cochrane Central Register of Controlled Trials, MEDLINE, EMBASE, trial registers, and bibliographies of trial reports. The full search was conducted in October 2011.
  
  
  METHODS
  Considered for inclusion were all randomised and quasi-randomised (method of allocating participants to a treatment which is not strictly random; e.g. by date of birth, hospital record number or alternation) controlled trials that compared surgical with non-surgical intervention for humeral shaft fractures in adults.
  
  
  METHODS
  Two authors independently selected and assessed potential eligible studies for inclusion.
  
  
  RESULTS
  We found six completed studies that appeared to meet our inclusion criteria. After scrutiny, we excluded all six studies: five were retrospective studies and one was a prospective study without randomisation. We identified three potentially eligible ongoing studies, two of which involve randomisation of treatment allocation and one, which we excluded, that does not.
  
  
  CONCLUSIONS
  There is no evidence available from randomised controlled trials to ascertain whether surgical intervention of humeral shaft fractures gives a better or worse outcome than no surgery. Sufficiently powered good quality multi-centre randomised controlled trials comparing surgical versus non-surgical interventions for treating humeral shaft fractures in adults are needed. It is likely that the results from the two ongoing randomised trials on this topic will help inform practice in due course.
authors.affiliation: Department of Surgery and Orthopaedic Surgery, Viecuri Medical Centre of Northern Limburg, Venlo, Netherlands.mauritsgosler@gmail.com.
authors.forename: Maurits W
authors.initials: MW
authors.lastname: Gosler
authors.forename: Mark
authors.initials: M
authors.lastname: Testroote
authors.forename: J W
authors.initials: JW
authors.lastname: Morrenhof
authors.forename: Heinrich M J
authors.initials: HM
authors.lastname: Janzing
mesh_terms: D000328:Adult; D018483:Diaphyses / Q000293:injuries; D005592:Fracture Fixation / Q000379:methods*; D006801:Humans; D006810:Humeral Fractures / Q000628:therapy*