title: Ponatinib: targeting the T315I mutation in chronic myelogenous leukemia.
authors.affiliation: Department of Hematology/Oncology, University of California-San Francisco, San Francisco, California, USA.
authors.forename: Neil P
authors.initials: NP
authors.lastname: Shah
mesh_terms: D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D035843:Biomedical Research; D017321:Clinical Trials, Phase I as Topic; D016044:Fusion Proteins, bcr-abl / Q000037:antagonists & inhibitors* / Q000235:genetics*; D006801:Humans; D007093:Imidazoles / Q000008:administration & dosage / Q000627:therapeutic use*; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000188:drug therapy* / Q000235:genetics*; D058990:Molecular Targeted Therapy; D009154:Mutation; D011724:Pyridazines / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D000970:Antineoplastic Agents; D007093:Imidazoles; D011724:Pyridazines; C545373:ponatinib; D016044:Fusion Proteins, bcr-abl