title: Synthesis of conjugated allenes through copper-catalyzed γ-selective and stereospecific coupling between propargylic phosphates and aryl- or alkenylboronates.
abstract: A Cu-catalyzed γ-selective coupling reaction between propargylic phosphates and aryl- or alkenylboronates afforded aryl- or alkenyl-conjugated allenes. The reaction showed excellent functional group compatibility in both the propargylic substrates and the boronates. The reaction of an enantioenriched propargylic phosphate proceeded with excellent chirality transfer with 1,3-anti stereochemistry to give axially chiral aryl- and alkenylallenes.
authors.affiliation: Department of Chemistry, Faculty of Science, Hokkaido University, Sapporo 060-0810, Japan.
authors.forename: Mingyu
authors.initials: M
authors.lastname: Yang
authors.forename: Natsumi
authors.initials: N
authors.lastname: Yokokawa
authors.forename: Hirohisa
authors.initials: H
authors.lastname: Ohmiya
authors.forename: Masaya
authors.initials: M
authors.lastname: Sawamura