title: Serum levels of leptin, adiponectin and resistin are interrelated and related to total antioxidant capacity, free fatty acids and phospholipids in early neonatal life.
abstract: OBJECTIVE
  The aims of this study were to determine interrelationships between serum leptin, adiponectin and resistin, insulin-like growth factor-1 (IGF-1), total antioxidant capacity (TAC), non-esterified fatty acids (NEFA) and phospholipids concentrations in infants.
  
  
  METHODS
  A cross-sectional study was conducted to assess serum levels of leptin, adiponectin, resistin, IGF-1, TAC, NEFA and phospholipids in 45 breast-fed infants enrolled at 4-30 days after birth.
  
  
  RESULTS
  Serum leptin and adiponectin concentrations were positively correlated. Serum resistin concentrations were inversely correlated to serum leptin and adiponectin concentrations. Serum TAC was positively correlated to serum leptin and adiponectin, and inversely to serum resistin concentrations. Serum adiponectin concentrations were positively related to serum NEFA and phospholipid concentrations. Serum resistin concentrations were inversely related to serum NEFA, and phospholipid concentrations.
  
  
  CONCLUSIONS
  These data show that circulatory levels of leptin, adiponectin and resistin are interrelated and they apparently interact with the anti-oxidant system of infants.
authors.affiliation: Department of Biochemistry, Uludag University Medical School, Bursa, Turkey. yesim@uludag.edu.tr
authors.forename: Yesim
authors.initials: Y
authors.lastname: Ozarda
authors.forename: Gul Ozlem
authors.initials: GO
authors.lastname: Tuncer
authors.forename: Yeliz
authors.initials: Y
authors.lastname: Gunes
authors.forename: Esma
authors.initials: E
authors.lastname: Eroz
mesh_terms: D052242:Adiponectin / Q000097:blood*; D000975:Antioxidants / Q000032:analysis*; D001942:Breast Feeding; D002657:Child Development; D003430:Cross-Sectional Studies; D005230:Fatty Acids, Nonesterified / Q000097:blood*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007334:Insulin-Like Growth Factor I / Q000032:analysis; D020738:Leptin / Q000097:blood*; D008297:Male; D010743:Phospholipids / Q000097:blood*; D010865:Pilot Projects; D052243:Resistin / Q000097:blood*; D014421:Turkey
chemical_list: C499918:ADIPOQ protein, human; D052242:Adiponectin; D000975:Antioxidants; D005230:Fatty Acids, Nonesterified; D020738:Leptin; D010743:Phospholipids; C499624:RETN protein, human; D052243:Resistin; D007334:Insulin-Like Growth Factor I