title: A method for identifying the origin of chondroitin sulfate with near infrared spectroscopy.
abstract: The object of this study was to explore the feasibility of support vector machine (SVM) to identify the origin of chondroitin sulfate (CS) by near infrared spectroscopy. 96 batches CS from three different origins were collected in this research, 66 batches of which were chosen for training set by Kennard-Stone (KS) method and the rest were used for testing. Through the comparison of pretreatment methods of standard normal variate transformation (SNV), multiplicative scatter correction (MSC), Savitzky-Golay (SG) smoothing and derivative with SG smoothing, a SVM discrimination model was constructed, of which the prediction result is 100% accurate with the pretreatment of first derivative and SG smoothing with 15 points. The result indicated that it had great potential using SVM to identify the origin of CS.
authors.affiliation: National Glycoengineering Research Center and School of Pharmaceutical Science, Shandong University, No. 44 Wenhuaxi Road, Jinan 250012, China.
authors.forename: Hengchang
authors.initials: H
authors.lastname: Zang
authors.forename: Lian
authors.initials: L
authors.lastname: Li
authors.forename: Fengshan
authors.initials: F
authors.lastname: Wang
authors.forename: Qiong
authors.initials: Q
authors.lastname: Yi
authors.forename: Qin
authors.initials: Q
authors.lastname: Dong
authors.forename: Chunxiao
authors.initials: C
authors.lastname: Sun
authors.forename: Jinfeng
authors.initials: J
authors.lastname: Wang
mesh_terms: D000818:Animals; D002417:Cattle; D002809:Chondroitin Sulfates / Q000737:chemistry* / Q000378:metabolism; D005240:Feasibility Studies; D008956:Models, Chemical; D012754:Sharks; D019265:Spectroscopy, Near-Infrared / Q000379:methods*; D060388:Support Vector Machine; D013552:Swine
chemical_list: D002809:Chondroitin Sulfates