title: [Clinical study of chronic invasive sinusitis caused by dematiaceous fungi].
abstract: OBJECTIVE
  To discuss the clinical presentation, diagnostic criterion and treatment principle of chronic invasive sinusitis caused by dematiaceous fungi.
  
  
  METHODS
  One patient was diagnosed as chronic invasive sinusitis based on history, headache, especially eye symptoms without fever, sinus CT and MRI, endoscopic and cytological findings in the nasal cavity. Surgical debridement was performed, and the patient was administered with systemic anti-fungi treatment.
  
  
  RESULTS
  Alternaria was identified on culture. The patient was proved of tissue invasion histopathologically through biopsy. The patient survived after treatment without recurrence.
  
  
  CONCLUSIONS
  Extensive and aggressive surgical debridement, prompt and adequate dosage of intravenous antifungal therapy , together with controlling of the underlying disease, all contribute to a complete resolution of the disease.
authors.affiliation: Department of Otolaryngology, the Third Hospital, Peking University, Beijing, 100191, China. fgl1219@163.com
authors.forename: Gaoli
authors.initials: G
authors.lastname: Fang
authors.forename: Qiuhang
authors.initials: Q
authors.lastname: Zhang
authors.forename: Li
authors.initials: L
authors.lastname: Zhu
authors.forename: Dongming
authors.initials: D
authors.lastname: Li
mesh_terms: D000528:Alternaria; D005260:Female; D006801:Humans; D008875:Middle Aged; D009181:Mycoses / Q000382:microbiology* / Q000628:therapy; D012852:Sinusitis / Q000382:microbiology* / Q000628:therapy