title: [Community-acquired methicillin resistant Staphylococcus aureus skin and soft tissue infections in Madrid: prevalence study].
abstract: BACKGROUND
  Since it was first described in the 1990s, Methicillin-Resistant Staphylococcus aureus infection among people with no contact with a hospital setting or with no traditional risk factors, has spread worldwide and is now an important epidemiological and public health problem.
  
  
  METHODS
  The present prospective and observational study was carried out from April to November 2010. All adult patients with community-acquired suppurative skin and soft tissue infection (SSTI) attending the Emergency Department were enrolled. Clinical, microbiological and epidemiological features of the infection were assessed.
  
  
  RESULTS
  A total of 59 samples were collected from 59 patients and CA-MRSA was isolated in 13 of them. Prevalence of CA-MRSA in patients with suppurative SSTI seen in the emergency department was 22.03%, and was 33.3% in patients with staphylococcal infection. Is worth noting the greater presence of necrosis detected in CA-MRSA lesions. Only 3 patients required hospital admission. Eleven of the 13 strains were Panton-Valentine leucocidin producers, and 5 were resistant to non-betalactam antibiotics. CA MRSA infection is still more frequent in the immigrant population.
  
  
  CONCLUSIONS
  Data on CA-MRSA prevalence in Spain are sparse. This study aims to emphasise the current importance of this emergent pathogen in our area. About one third of suppurative staphylococcal SSTI presenting in our emergency department are caused by this agent, confirming a rapid spread in our country. Some clinical features, such as the high presence of necrosis, are closely related to CA-MRSA.
authors.affiliation: Servicio de Dermatología, Hospital Universitario La Paz, Madrid, España. beacasadoverrier@gmail.com
authors.forename: Beatriz
authors.initials: B
authors.lastname: Casado-Verrier
authors.forename: Cristina
authors.initials: C
authors.lastname: Gómez-Fernández
authors.forename: José Ramón
authors.initials: JR
authors.lastname: Paño-Pardo
authors.forename: Rosa
authors.initials: R
authors.lastname: Gómez-Gil
authors.forename: Jesús
authors.initials: J
authors.lastname: Mingorance-Cruz
authors.forename: Ricardo
authors.initials: R
authors.lastname: Moreno-Alonso de Celada
authors.forename: Pedro
authors.initials: P
authors.lastname: Herranz-Pinto
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001427:Bacterial Toxins / Q000032:analysis; D002353:Carrier State / Q000453:epidemiology; D003131:Combined Modality Therapy; D017714:Community-Acquired Infections / Q000453:epidemiology* / Q000382:microbiology / Q000473:pathology; D004322:Drainage; D024901:Drug Resistance, Multiple, Bacterial; D004636:Emergency Service, Hospital / Q000706:statistics & numerical data; D054242:Emigrants and Immigrants / Q000706:statistics & numerical data; D005098:Exotoxins / Q000032:analysis; D005260:Female; D006785:Hospitals, University / Q000706:statistics & numerical data; D006801:Humans; D007956:Leukocidins / Q000032:analysis; D008297:Male; D055624:Methicillin-Resistant Staphylococcus aureus / Q000302:isolation & purification*; D008875:Middle Aged; D009336:Necrosis; D010343:Patient Admission / Q000706:statistics & numerical data; D015995:Prevalence; D011446:Prospective Studies; D018461:Soft Tissue Infections / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology / Q000473:pathology / Q000601:surgery; D013030:Spain / Q000453:epidemiology; D013203:Staphylococcal Infections / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology / Q000473:pathology / Q000601:surgery; D013207:Staphylococcal Skin Infections / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology / Q000473:pathology / Q000601:surgery; D014505:Urban Population / Q000706:statistics & numerical data; D055815:Young Adult
chemical_list: D000900:Anti-Bacterial Agents; D001427:Bacterial Toxins; D005098:Exotoxins; D007956:Leukocidins; C078284:Panton-Valentine leukocidin