title: Efficient palladium-catalyzed cross-coupling of highly acidic substrates, nitroacetates.
abstract: Palladium-catalyzed cross-coupling conditions were developed that efficiently afford 2-aryl-2-nitroacetates from aryl bromides and the very acidic nitroacetates.
authors.affiliation: Penn Merck High Throughput Experimentation Laboratory, Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania 1910-6323, USA.
authors.forename: Alison E
authors.initials: AE
authors.lastname: Metz
authors.forename: Simon
authors.initials: S
authors.lastname: Berritt
authors.forename: Spencer D
authors.initials: SD
authors.lastname: Dreher
authors.forename: Marisa C
authors.initials: MC
authors.lastname: Kozlowski
mesh_terms: D000085:Acetates / Q000737:chemistry*; D002384:Catalysis; D006863:Hydrogen-Ion Concentration; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*
chemical_list: D000085:Acetates; D010165:Palladium; C028257:nitroacetic acid