title: [Unsuccessful treatment with OK-432 picibanil for orbital lymphangioma].
abstract: BACKGROUND
  Lymphangioma is a malformation of the lymphatic system. The classic approach is surgery. We report a case of orbital lymphangioma in a girl who was given OK-432 to avoid surgery and its complications.
  
  
  CONCLUSIONS
  OK-432 is a lyophilized mixture of group A Streptococcus pyogenes which produces a fibrosis limited to the lesion with a high cure rate. The main advantages are the easy intra-lesional application. with no scars and or damage of closed areas. Its main disadvantage is a significant local inflammatory reaction.
authors.affiliation: Servicio de Oftalmología, Hospital General de Castellón, Castellón, España. lanuza.amp@gva.es
authors.forename: A
authors.initials: A
authors.lastname: Lanuza García
authors.forename: R
authors.initials: R
authors.lastname: Bañón Navarro
authors.forename: A
authors.initials: A
authors.lastname: Llorca Cardeñosa
authors.forename: C
authors.initials: C
authors.lastname: Delgado Navarro
mesh_terms: D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000970:Antineoplastic Agents / Q000009:adverse effects / Q000627:therapeutic use*; D001763:Blepharoptosis / Q000209:etiology; D005141:Eyelid Diseases / Q000139:chemically induced; D005260:Female; D006406:Hematoma / Q000139:chemically induced; D006801:Humans; D008202:Lymphangioma / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D008279:Magnetic Resonance Imaging; D009918:Orbital Neoplasms / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D010844:Picibanil / Q000009:adverse effects / Q000627:therapeutic use*; D012597:Sclerosing Solutions / Q000009:adverse effects / Q000627:therapeutic use*; D017211:Treatment Failure
chemical_list: D000305:Adrenal Cortex Hormones; D000970:Antineoplastic Agents; D012597:Sclerosing Solutions; D010844:Picibanil