title: Olanzapine-induced eccrine squamous syringometaplasia.
abstract: Eccrine squamous syringometaplasia is a histopathologic pattern that has mainly been described in patients receiving chemotherapy. Its association to nonchemotherapeutic agents is rare, with very few cases reported in the literature. We present the case of a 55-year-old patient with schizophrenia, who developed a skin eruption 5 weeks after initiating treatment with olanzapine. The histopathologic study revealed squamous syringometaplasia of the dermal eccrine ducts.
authors.affiliation: Department of Dermatology, Fundación Jiménez Díaz, Universidad Autónoma, Madrid, Spain. anamolina6@hotmail.com
authors.forename: Ana María
authors.initials: AM
authors.lastname: Molina-Ruiz
authors.forename: Rosa Maria
authors.initials: RM
authors.lastname: Molina-Ruiz
authors.forename: Teresa
authors.initials: T
authors.lastname: Zulueta
authors.forename: Román
authors.initials: R
authors.lastname: Barabash
authors.forename: Luis
authors.initials: L
authors.lastname: Requena
mesh_terms: D014150:Antipsychotic Agents / Q000009:adverse effects*; D001569:Benzodiazepines / Q000009:adverse effects*; D001706:Biopsy; D003879:Dermatologic Agents / Q000627:therapeutic use; D057915:Drug Substitution; D004439:Eccrine Glands / Q000187:drug effects* / Q000473:pathology; D006801:Humans; D008297:Male; D008679:Metaplasia; D008875:Middle Aged; D000077152:Olanzapine; D018967:Risperidone / Q000627:therapeutic use; D012559:Schizophrenia / Q000188:drug therapy*; D013544:Sweat Gland Neoplasms / Q000139:chemically induced* / Q000188:drug therapy / Q000473:pathology; D016896:Treatment Outcome
chemical_list: D014150:Antipsychotic Agents; D003879:Dermatologic Agents; D001569:Benzodiazepines; D018967:Risperidone; D000077152:Olanzapine