title: Bioacoustics response of small benign or malignant nodules.
abstract: One of the most important features of separation between benign or malignant tissues is their smooth or rough shape. This article presents a new method for early diagnosis of thyroid cancer by knowing the resonance frequencies of a certain tissue. Two types of nodules were investigated: spherical and elliptical. Their external surfaces were smooth or rough with different values of spicules. Propagation of sound through the human body was modeled by a classical partial differential equation associated with Neumann or Dirichlet boundary conditions. The assessments of about ten acoustic eigenfrequencies are enough to decide the type of external surfaces: smooth or rough, or whether nodule is benign or malignant. Data obtained by this method refers to the result of investigating 3D bodies smaller than 5 mm, when other medical devices such as ultrasound or CT cannot evaluate their surface shape because of their limited spatial resolution.
authors.affiliation: University of Pitesti, Pitesti 11084, Romania. ggavriloaia@gmail.com
authors.forename: Gheorghe V
authors.initials: GV
authors.lastname: Gavriloaia
authors.forename: Mariuca-Roxana G
authors.initials: MR
authors.lastname: Gavriloaia
authors.forename: Marian L
authors.initials: ML
authors.lastname: Novac
mesh_terms: D000162:Acoustics; D006801:Humans; D013057:Spectrum Analysis; D013964:Thyroid Neoplasms / Q000175:diagnosis* / Q000473:pathology*