title: [The roles of microRNA in the diagnosis and therapy for cardiovascular diseases].
abstract: Recent years, microRNAs (miRNAs) have attracted scholars' attention extensively. MiRNAs are a class of 21-25-nucleotide non-coding RNAs that have been implicated in regulating gene transcription and expression. Thus, alteration of miRNA is involved in many human activities and diseases. The function of miRNA is varied dependence on cell type and target mRNA. MiRNAs play important roles in the process of injury and repair through affecting cell phenotypes, such as development, division, proliferation, apoptosis and regeneration. Recently, miRNA-based findings seem to be promising implications for diagnosis and therapy.
authors.affiliation: Institute of Vascular Medicine, Peking University Third Hospital, Reference Laboratory of Ministry of Health on Cardiovascular Molecular Biology and Regulatory Peptides, Beijing 100191, China.
authors.forename: Jin
authors.initials: J
authors.lastname: Tao
authors.forename: Su-Fang
authors.initials: SF
authors.lastname: Li
authors.forename: Ming
authors.initials: M
authors.lastname: Xu
mesh_terms: D000818:Animals; D015415:Biomarkers / Q000378:metabolism*; D002318:Cardiovascular Diseases / Q000175:diagnosis* / Q000378:metabolism / Q000628:therapy; D005786:Gene Expression Regulation; D006333:Heart Failure / Q000175:diagnosis / Q000378:metabolism / Q000628:therapy; D006801:Humans; D035683:MicroRNAs / Q000378:metabolism / Q000502:physiology*; D009203:Myocardial Infarction / Q000175:diagnosis / Q000378:metabolism / Q000628:therapy
chemical_list: D015415:Biomarkers; D035683:MicroRNAs