title: Colorful calcium sensors.
abstract: (R)evolution of protein-based calcium sensors: Expanding the toolbox of genetically encoded calcium sensors with new colors and traits is important for understanding calcium signaling and its relation to other intracellular pathways. Campbell and co-workers have used a new directed-evolution strategy to develop a rich palette of new sensors, including the first red-shifted, genetically encoded calcium sensor.
authors.affiliation: Laboratory of Chemical Biology, Department of Biomedical Engineering, Eindhoven University of Technology, Den Dolech 2, 5612 AZ Eindhoven (The Netherlands).
authors.forename: Laurens
authors.initials: L
authors.lastname: Lindenburg
authors.forename: Maarten
authors.initials: M
authors.lastname: Merkx
mesh_terms: D002118:Calcium / Q000032:analysis* / Q000378:metabolism; D020013:Calcium Signaling; D005456:Fluorescent Dyes / Q000737:chemistry*; D008164:Luminescent Proteins / Q000737:chemistry
chemical_list: D005456:Fluorescent Dyes; D008164:Luminescent Proteins; D002118:Calcium