title: Selective stabilization of self-assembled hydrogen-bonded molecular capsules through π-π interactions.
abstract: Subtle noncovalent forces such as π-π interactions play an import role in the folding of biological macromolecules such as DNA and proteins. We describe here a system where such interactions on the outside of a molecular capsule trigger a selective change of its structure as a self-assembled receptor.
authors.affiliation: The Skaggs Institute for Chemical Biology and Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA.
authors.forename: Konrad
authors.initials: K
authors.lastname: Tiefenbacher
authors.forename: Julius
authors.initials: J
authors.lastname: Rebek
mesh_terms: D002214:Capsules; D002625:Chemistry, Organic / Q000379:methods*; D002627:Chemistry, Physical / Q000379:methods; D004247:DNA / Q000737:chemistry*; D019281:Dimerization; D006859:Hydrogen; D006860:Hydrogen Bonding; D046911:Macromolecular Substances; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D008968:Molecular Conformation; D015394:Molecular Structure; D011487:Protein Conformation; D017510:Protein Folding; D011506:Proteins / Q000737:chemistry; D014508:Urea / Q000737:chemistry
chemical_list: D002214:Capsules; D046911:Macromolecular Substances; D011506:Proteins; D006859:Hydrogen; D014508:Urea; D004247:DNA