title: [Radiation-induced sarcoma of the head and neck].
abstract: BACKGROUND
  Radiation-induced sarcoma (RIS) of the head and neck is a late and rare complication of cancer treatment by radiation therapy. It occurs mostly within the limits of the irradiated area. Its incidence is increasing and related to an improved survival rate of treated patients. But it does not rule out the use of radiotherapy in the treatment of this cancer.
  
  
  METHODS
  We report two cases of sarcoma having appeared in the irradiated area, in patients treated by adjuvant radiotherapy for head and neck neoplasm.
  
  
  CONCLUSIONS
  The prognosis for this sarcoma depends mainly on how early the diagnosis is made and the quality of surgical resection. Adjuvant chemotherapy or radiotherapy can be considered. Ongoing research on the expression of RIS genes could soon lead to new treatments.
authors.affiliation: Service de Chirurgie Maxillo-Faciale et Réparatrice, CHU Dupuytren de Limoges, 2, avenue Martin-Luther-King, 87042 Limoges cedex, France. justine.lerat@gmail.com
authors.forename: J
authors.initials: J
authors.lastname: Lerat
authors.forename: A-F
authors.initials: AF
authors.lastname: Perez
authors.forename: P
authors.initials: P
authors.lastname: Osenda
authors.forename: X
authors.initials: X
authors.lastname: Zasadny
authors.forename: J
authors.initials: J
authors.lastname: Brie
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000532:radiotherapy; D005260:Female; D006258:Head and Neck Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000209:etiology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008441:Maxillary Neoplasms / Q000532:radiotherapy; D008875:Middle Aged; D009381:Neoplasms, Radiation-Induced / Q000175:diagnosis* / Q000000981:diagnostic imaging; D012509:Sarcoma / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000209:etiology; D014057:Tomography, X-Ray Computed; D014062:Tongue Neoplasms / Q000532:radiotherapy