title: Quetiapine-induced frequent premature ventricular contraction.
abstract: A 17-year-old female diagnosed with bipolar II disorder was treated for emotional lability with quetiapine. Two-lead electrocardiography revealed frequent monomorphic premature ventricular contraction (PVC) during an electroencephalography examination. Twenty-four-hour Holter electrocardiography revealed 0.6% uniform frequent PVCs and indicated that the readministration and second-time withdrawal of quetiapine markedly increased (7.1%) and decreased the frequency of PVC (1.1%), respectively. This case indicates that quetiapine can cause PVC as a serious side effect.
authors.affiliation: Department of Psychiatry, Kagoshima University Graduate School of Medical and Dental Sciences, 1-35-8 Sakuragaoka, Kagoshima, Kagoshima 890-8520, Japan.
authors.forename: Akiko
authors.initials: A
authors.lastname: Deguchi
authors.forename: Masayuki
authors.initials: M
authors.lastname: Nakamura
authors.forename: Takehiro
authors.initials: T
authors.lastname: Hayashi
authors.forename: Akira
authors.initials: A
authors.lastname: Sano
mesh_terms: D000293:Adolescent; D014150:Antipsychotic Agents / Q000009:adverse effects*; D003987:Dibenzothiazepines / Q000009:adverse effects*; D004562:Electrocardiography; D004569:Electroencephalography; D005260:Female; D006801:Humans; D000069348:Quetiapine Fumarate; D018879:Ventricular Premature Complexes / Q000139:chemically induced*
chemical_list: D014150:Antipsychotic Agents; D003987:Dibenzothiazepines; D000069348:Quetiapine Fumarate