title: On osseointegration: the healing adaptation principle in the context of osseosufficiency, osseoseparation, and dental implant failure.
abstract: The host-implant interface is remarkably enduring given the functional and biologic challenges it faces, and our success in assisting patients to lead better lives because of implant biotechnology is the envy of many other health care practitioners. It is therefore vital that dentists accept that clinically significant marginal bone loss is uncommon and that implant failure is rare. In this paper, important elements regarding why implants experience marginal bone loss, why implants may fail as a result of such bone loss, and how to describe the continuum of bone loss with respect to patient-mediated outcomes are outlined.
authors.affiliation: Division of Prosthodontics, Mayo Clinic, Rochester, Minnesota, USA. koka.sreenivas@mayo.edu
authors.forename: Sreenivas
authors.initials: S
authors.lastname: Koka
authors.forename: George
authors.initials: G
authors.lastname: Zarb
mesh_terms: D000222:Adaptation, Physiological / Q000502:physiology; D016301:Alveolar Bone Loss / Q000503:physiopathology*; D015921:Dental Implants; D017267:Dental Prosthesis Design; D019232:Dental Restoration Failure; D004955:Esthetics, Dental; D005891:Gingivitis / Q000503:physiopathology; D006801:Humans; D009910:Oral Hygiene; D016348:Osseointegration / Q000502:physiology*; D011379:Prognosis; D012307:Risk Factors; D016019:Survival Analysis; D013997:Time Factors; D016896:Treatment Outcome; D014945:Wound Healing / Q000502:physiology
chemical_list: D015921:Dental Implants