title: Prevalence of hyperprolactinemia in adolescents and young women with menstruation-related problems.
abstract: OBJECTIVE
  The aim of this study was to evaluate the prevalence of hyperprolactinemia in adolescents and young women with menstrual problems.
  
  
  METHODS
  This study included 1704 young women with menstruation-related problems. The patients were classified into group I (age, 11-20 years) or group II (age, 21-30 years); the prevalence of hyperprolactinemia was analyzed according to age and categories of menstruation-related problems.
  
  
  RESULTS
  For primary amenorrhea and oligomenorrhea, the prevalence of hyperprolactinemia was low in both groups. However, hyperprolactinemia was a relatively common cause of secondary amenorrhea (5.5% for group I and 13.8% for group II, respectively); it was more frequent in group II (P = .001); the prevalence of prolactinoma was also higher in group II (P = .015). For abnormal uterine bleeding, hyperprolactinemia was more common in group II (2.6% for group I and 9.4% for group II; P < .001), but causes were similar.
  
  
  CONCLUSIONS
  Hyperprolactinemia is not rare in young women with menstruation-related problems; its prevalence varies according to age and manifestations.
authors.affiliation: Department of Obstetrics and Gynecology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
authors.forename: Dong-Yun
authors.initials: DY
authors.lastname: Lee
authors.forename: Yoon-Kyung
authors.initials: YK
authors.lastname: Oh
authors.forename: Byung-Koo
authors.initials: BK
authors.lastname: Yoon
authors.forename: DooSeok
authors.initials: D
authors.lastname: Choi
mesh_terms: D000293:Adolescent; D000328:Adult; D000568:Amenorrhea / Q000097:blood / Q000453:epidemiology*; D002648:Child; D005260:Female; D006801:Humans; D006966:Hyperprolactinemia / Q000097:blood / Q000453:epidemiology*; D008796:Metrorrhagia / Q000097:blood / Q000453:epidemiology; D009839:Oligomenorrhea / Q000097:blood / Q000453:epidemiology*; D015995:Prevalence; D011388:Prolactin / Q000097:blood; D015175:Prolactinoma / Q000097:blood / Q000453:epidemiology; D055815:Young Adult
chemical_list: D011388:Prolactin