title: A copper-based catalytic system for carboxylation of terminal alkynes: synthesis of alkyl 2-alkynoates.
abstract: An efficient coupling of terminal alkynes and CO(2) in the presence of alkyl halides can be achieved under ambient conditions using a copper/phosphine catalyst system, providing facile access to a variety of functionalised alkyl 2-alkynoates.
authors.affiliation: Graduate School of Pharmaceutical Sciences, Tohoku University, 6-3, Aoba, Aramaki, Aoba-ku, Sendai 980-8578, Japan. inamoto@mail.pharm.tohoku.ac.jp
authors.forename: Kiyofumi
authors.initials: K
authors.lastname: Inamoto
authors.forename: Narumi
authors.initials: N
authors.lastname: Asano
authors.forename: Koji
authors.initials: K
authors.lastname: Kobayashi
authors.forename: Misato
authors.initials: M
authors.lastname: Yonemoto
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Kondo
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D002245:Carbon Dioxide / Q000737:chemistry; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D015394:Molecular Structure
chemical_list: D000480:Alkynes; D002245:Carbon Dioxide; D003300:Copper