title: Illusion of stroke: intravascular lymphomatosis.
abstract: We describe an unusual case of cerebral intravascular lymphomatosis wherein the         patient presented with multiple embolic strokes predominantly in the posterior         circulation. Using this case as an illustration, we review the literature of this         malignancy, which consists of extranodal diffuse large B-cell lymphoma. For patients         with recurrent stroke-like events without cardiac risk factors, the accurate diagnosis         requires a high index of suspicion by the neurologist and a brain biopsy specimen         demonstrating lymphoma cells within the lumen of cerebral blood vessels.         Intravascular lymphomatosis can be treated with systemic chemotherapies, but the         response rate and pattern of relapse remain unknown.
authors.affiliation: Department of Neurology, Harvard Medical School, Boston, MA, USA.
authors.forename: Soma
authors.initials: S
authors.lastname: Sengupta
authors.forename: Nigel P
authors.initials: NP
authors.lastname: Pedersen
authors.forename: James E
authors.initials: JE
authors.lastname: Davis
authors.forename: Rafael
authors.initials: R
authors.lastname: Rojas
authors.forename: Hasini
authors.initials: H
authors.lastname: Reddy
authors.forename: Ekkehard
authors.initials: E
authors.lastname: Kasper
authors.forename: Patricia
authors.initials: P
authors.lastname: Greenstein
authors.forename: Eric T
authors.initials: ET
authors.lastname: Wong
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use; D002536:Cerebral Arteries / Q000473:pathology*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D016403:Lymphoma, Large B-Cell, Diffuse / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology; D020521:Stroke / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology
chemical_list: D000970:Antineoplastic Agents