title: The MacNew Heart Disease Health-Related Quality of Life Questionnaire in patients with angina and patients with ischemic heart failure.
abstract: OBJECTIVE
  Patient-reported outcomes including health-related quality of life are important in clinical care and research studies. The MacNew Heart Disease Health-Related Quality Of Life Questionnaire has been validated in English-speaking patients with myocardial infarction. The aim of this study was to validate the MacNew in English-speaking patients with angina or ischemic heart failure.
  
  
  METHODS
  Canadian and American patients with angina or ischemic heart failure completed the MacNew, the Short Form-36 Health Survey, and the Hospital Anxiety and Depression Scale.
  
  
  RESULTS
  We administered questionnaires to 276 patients with angina (mean age, 65.9 years) and 155 patients with ischemic heart failure (mean age, 70.3 years). The mean ± SD MacNew global score in patients with ischemic heart failure (5.1 ± 1.2) was statistically (P < 0.001), but not clinically, poorer than in patients with angina (5.3 ± 1.1). The three-factor measurement model explained 46.1% of the observed variance in the MacNew in patients with angina and 46.5% in patients with ischemic heart failure. Internal consistency was ≥0.90, and test-retest reliability was ≥0.70 for each MacNew scale and the a priori convergent and discriminative validity hypotheses were confirmed in both diagnoses. The MacNew was highly accepted by patients with little respondent or administrative burden.
  
  
  CONCLUSIONS
  The English version of the MacNew is reliable and valid in patients with angina or ischemic heart failure. This permits health-related quality of life outcome comparisons in patients with angina, ischemic heart failure, and myocardial infarction with the MacNew and provides a better understanding of the full range of health-related quality of life outcomes.
authors.affiliation: Department of Medical Psychology, Innsbruck Medical University, Innsbruck, Austria. stefan.hoefer@i-med.ac.at
authors.forename: Stefan
authors.initials: S
authors.lastname: Höfer
authors.forename: Atif
authors.initials: A
authors.lastname: Saleem
authors.forename: James
authors.initials: J
authors.lastname: Stone
authors.forename: Randal
authors.initials: R
authors.lastname: Thomas
authors.forename: Heather
authors.initials: H
authors.lastname: Tulloch
authors.forename: Neil
authors.initials: N
authors.lastname: Oldridge
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000787:Angina Pectoris / Q000503:physiopathology / Q000523:psychology*; D005260:Female; D006304:Health Status; D006333:Heart Failure / Q000503:physiopathology / Q000523:psychology*; D006801:Humans; D007802:Language; D008297:Male; D008603:Mental Health; D008875:Middle Aged; D009203:Myocardial Infarction / Q000503:physiopathology / Q000523:psychology*; D017202:Myocardial Ischemia / Q000503:physiopathology / Q000523:psychology*; D011594:Psychometrics; D011788:Quality of Life; D015203:Reproducibility of Results; D011795:Surveys and Questionnaires