title: Efficacy of glycopyrrolate in primary hyperhidrosis patients.
abstract: BACKGROUND
  Primary hyperhidrosis is a disorder of excessive sweating, which shares several features with anxiety disorders and has a negative impact on a patient's quality of life. Oral glycopyrrolate is one of the treatments available. There are a few published studies on the use of glycopyrrolate given orally in the treatment of hyperhidrosis.
  
  
  METHODS
  Thies is study was a review of case notes in a series of 36 patients with primary hyperhidrosis. We made a comparison between the Keller's scale score of a pre-glycopyrrolate medication group and the Keller's scale score f a post-glycopyrrolate medication group. The Milanez de Campos score, Short Form_36 (SF-36) score, Beck Depression Inventory (BDI) score, Beck Anxiety Inventory (BAI) score, and autonomic nervous system (ANS) scale score were also compared between the two groups.
  
  
  RESULTS
  In the post-glycopyrrolate medication group, there were declines in Keller's scale, and Milanez de Campos scale score and BAI score (P < 0.001). In addition, there were increases in SF_36 score in the post-glycopyrrolate medication group (P = 0.03) However, no changes were seen in, BDI score and ANS score in the post-glycopyrrolate medication group (P < 0.001).
  
  
  CONCLUSIONS
  Glycopyrrolate is an effective initial method of treating primary hyperhidrosis that, reduces anxiety and improve patients' quality of life.
authors.affiliation: Department of Anesthesiology and Pain Medicine, Ajou University College of Medicine, Suwon, Korea.
authors.forename: Hyun Ho
authors.initials: HH
authors.lastname: Lee
authors.forename: Do Won
authors.initials: DW
authors.lastname: Kim
authors.forename: Do Wan
authors.initials: DW
authors.lastname: Kim
authors.forename: Chan
authors.initials: C
authors.lastname: Kim