title: Outcome of 19 dogs with parathyroid carcinoma after surgical excision.
abstract: Parathyroid carcinoma (PTC) is rare in dogs and there is little information documenting its treatment and prognosis. The objective of this study was to describe the outcome of dogs with PTC treated with surgical excision. Medical records of 19 dogs undergoing surgical excision of PTC between 1990 and 2010 were reviewed retrospectively. Dogs were presented for clinical hypercalcaemia or incidental hypercalcaemia noted by referring veterinarians on routine serum chemistry profiles. A parathyroid nodule was identified with cervical ultrasound in 17/17 dogs. Hypercalcaemia resolved in 18/19 dogs within 4 days postoperatively. Nine developed hypocalcaemia. None were confirmed to develop recurrent or metastatic PTC. The only death associated with PTC was a dog that was euthanized for intractable hypocalcaemia 9 days after surgery. Estimated 1-, 2- and 3-year survival rates were 72, 37 and 30%, respectively. Excision of PTC results in resolution of hypercalcaemia and excellent tumour control.
authors.affiliation: Department of Small Animal Medicine and Surgery, University of Georgia, College of Veterinary Medicine, Athens, GA 30602, USA.
authors.forename: E S
authors.initials: ES
authors.lastname: Sawyer
authors.forename: N C
authors.initials: NC
authors.lastname: Northrup
authors.forename: C W
authors.initials: CW
authors.lastname: Schmiedt
authors.forename: W T N
authors.initials: WT
authors.lastname: Culp
authors.forename: K M
authors.initials: KM
authors.lastname: Rassnick
authors.forename: L D
authors.initials: LD
authors.lastname: Garrett
authors.forename: K A
authors.initials: KA
authors.lastname: Selting
authors.forename: C F
authors.initials: CF
authors.lastname: Saba
authors.forename: E W
authors.initials: EW
authors.lastname: Howerth
mesh_terms: D000818:Animals; D002277:Carcinoma / Q000473:pathology / Q000601:surgery / Q000662:veterinary*; D004283:Dog Diseases / Q000473:pathology / Q000601:surgery*; D004285:Dogs; D005260:Female; D006934:Hypercalcemia / Q000150:complications / Q000662:veterinary; D008297:Male; D010282:Parathyroid Neoplasms / Q000150:complications / Q000473:pathology / Q000601:surgery / Q000662:veterinary*; D012189:Retrospective Studies; D016019:Survival Analysis; D016896:Treatment Outcome; D014481:United States