title: Exposure assessment of T2 and HT2 toxins in Catalonia (Spain).
abstract: HT-2 toxin (HT2) and T-2 toxin (T2) are mycotoxins produced in several cereals by species of Fusarium. The aim of the present study was to assess the exposure of Catalonian population to the combined mycotoxins T2 and HT2. Three different approaches were considered to handle the left censored data: (1) a substitution method, (2) a parametric method using the maximum likelihood estimation (MLE) and (3) a non-parametric method using the Kaplan-Meier (KM) estimator. Raw contamination data was provided by a large survey conducted in this region, in addition to the raw consumption data from a nutritional study specifically designed to assess the dietary intake of the main foodstuffs related to T2 and HT2 contamination for all population age groups. Contamination and consumption data were combined by simulation using a stochastic method. Accuracy and reliability of the statistic estimates were assessed building the related confidence intervals using a pseudo-parametric bootstrap method. Considering the results from the present study, the most exposed group population to the toxin T2 and HT2 should be expected to be the children.
authors.affiliation: Applied Mycology Unit, Food Technology Department, University of Lleida, XaRTA-UTPV, Lleida, Spain. gcano@tecal.udl.cat
authors.forename: G
authors.initials: G
authors.lastname: Cano-Sancho
authors.forename: S
authors.initials: S
authors.lastname: Marín
authors.forename: A J
authors.initials: AJ
authors.lastname: Ramos
authors.forename: V
authors.initials: V
authors.lastname: Sanchis
mesh_terms: D004781:Environmental Exposure; D005670:Fusarium / Q000737:chemistry; D006801:Humans; D009183:Mycotoxins / Q000633:toxicity*; D015203:Reproducibility of Results; D013030:Spain; D013269:Stochastic Processes
chemical_list: D009183:Mycotoxins