title: Genetic risk and gynecologic cancers.
abstract: Although most gynecologic malignancies are sporadic, hereditary cancer syndromes cause a substantial portion of these cancers. Given that the diagnosis of these syndromes has prognostic and therapeutic implications for the patient, as well as preventive implications for her family members, genetic testing is now an accepted part of the management of the patient who has gynecologic cancer.
authors.affiliation: Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, 77030-3721, USA.
authors.forename: Laura L
authors.initials: LL
authors.lastname: Holman
authors.forename: Karen H
authors.initials: KH
authors.lastname: Lu
mesh_terms: D003123:Colorectal Neoplasms, Hereditary Nonpolyposis / Q000235:genetics / Q000473:pathology; D005260:Female; D020022:Genetic Predisposition to Disease; D005833:Genital Neoplasms, Female / Q000175:diagnosis / Q000235:genetics* / Q000628:therapy; D061325:Hereditary Breast and Ovarian Cancer Syndrome / Q000235:genetics / Q000473:pathology; D006801:Humans; D012306:Risk