title: Endoscopic vs transfacial resection of sinonasal adenocarcinomas.
abstract: OBJECTIVE
  Compare the survival and the complication rates of 2 comparable groups of patients who underwent either endoscopic or transfacial resection of a sinonasal adenocarcinoma.
  
  
  METHODS
  Historical cohort study.
  
  
  METHODS
  Tertiary referral center.
  
  
  METHODS
  Twenty-four patients with sinonasal adenocarcinomas who recently underwent an endoscopy (the ENDO group, 1999-2009) were compared with 24 patients who underwent a lateral rhinotomy procedure (the LR group, 1993-2007). The present retrospective study included patients who would have had an endoscopic resection in 2011.
  
  
  RESULTS
  The groups were comparable in terms of age and sex (P = .49), as well as tumor stages; 43 of the 48 patients had undergone postoperative radiotherapy. There were 13 T1-T2 and 11 T3-T4 tumors in the ENDO group compared with 12 T1-T2 and 12 T3-T4 tumors in the LR group (P = .77). The mean length of follow-up was 38 months for the ENDO group and 89 for the LR group. The overall survival and recurrence-free rates were not significantly different (P = .3 and P = .87, respectively). The median duration of hospitalization was significantly shorter in the ENDO group than in the LR group (4 vs 8 days, P < .0001). The rate of early complications was identical in both groups (12.5%).
  
  
  CONCLUSIONS
  The endoscopic approach is a safe and effective treatment in selected sinonasal adenocarcinoma cases. The early oncological outcome and morbidity associated with the endoscopic approach were comparable with a transfacial approach. Hospitalization was significantly reduced by the endoscopic approach. Although the endoscopic approach is less invasive, it requires an optimal preoperative imaging protocol and an experienced surgical team.
authors.affiliation: Otorhinolaryngology-Head and Neck Surgery Department,University Hospital Rangueil-Larrey, Toulouse, France. vergez.s@chu-toulouse.fr
authors.forename: Sebastien
authors.initials: S
authors.lastname: Vergez
authors.forename: Nathalie
authors.initials: N
authors.lastname: Martin-Dupont
authors.forename: Benoit
authors.initials: B
authors.lastname: Lepage
authors.forename: Guillaume
authors.initials: G
authors.lastname: De Bonnecaze
authors.forename: Anne
authors.initials: A
authors.lastname: Decotte
authors.forename: Elie
authors.initials: E
authors.lastname: Serrano
mesh_terms: D000230:Adenocarcinoma / Q000000981:diagnostic imaging / Q000532:radiotherapy / Q000601:surgery*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016009:Chi-Square Distribution; D004724:Endoscopy; D005260:Female; D006801:Humans; D007902:Length of Stay / Q000706:statistics & numerical data; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D010255:Paranasal Sinus Neoplasms / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery*; D011183:Postoperative Complications; D011859:Radiography; D012189:Retrospective Studies; D015996:Survival Rate; D016896:Treatment Outcome