title: Eyelid nodule: a rare presentation of Langerhans cell histiocytosis.
abstract: Langerhans cell histiocytosis occurring as an isolated tumor of eyelid has rarely been reported. We report an unusual case of a 5-year-old boy who presented with a smooth nodular lesion over the right lower eyelid accompanied with hyperemia for a month. The biopsy and CD1a positivity confirmed it to be Langerhans cell histiocytosis. It was localized to the eyelid as no other organ was involved. Although Langerhans cell histiocytosis of the eyelid is exceptional, it must be included in the differential diagnosis of eyelid nodular lesions and the diagnostic and the subsequent management must be multidisciplinary.
authors.affiliation: Pediatric Hematology Oncology and Bone Marrow Transplant Unit, Center for Child Health, Sir Ganga Ram Hospital, Delhi, India.
authors.forename: Mohammed
authors.initials: M
authors.lastname: Ramzan
authors.forename: Satya Prakash
authors.initials: SP
authors.lastname: Yadav
authors.forename: Sunita
authors.initials: S
authors.lastname: Bhalla
authors.forename: Pallavi
authors.initials: P
authors.lastname: Jamwal
authors.forename: A K
authors.initials: AK
authors.lastname: Grover
authors.forename: Anupam
authors.initials: A
authors.lastname: Sachdeva
mesh_terms: D018949:Antigens, CD1 / Q000378:metabolism; D001706:Biopsy; D002675:Child, Preschool; D003937:Diagnosis, Differential; D005141:Eyelid Diseases / Q000378:metabolism / Q000473:pathology*; D006646:Histiocytosis, Langerhans-Cell / Q000378:metabolism / Q000473:pathology*; D006801:Humans; D006940:Hyperemia / Q000378:metabolism / Q000473:pathology; D008297:Male
chemical_list: D018949:Antigens, CD1; C419393:CD1a antigen