title: [Indices of tissue necrosis markers in acute pyo-destructive diseases of organs of the abdominal cavity].
abstract: Investigation of indices of lactate dehydrogenase (LDG) and creatine phosphokinase (CPK) in a group of patients with extensive necrotic alterations in organs of the abdominal cavity and in a group of patients without extensive necroses has shown that in the first group there were higher levels of LDG and CPK. It shows that the LDG and CPK indices may be used as markers of tissue necrosis of the abdominal organs. In addition, in patients who died against the background of growing polyorganic insufficiency the LDG and CPK level by the end of treatment was statistically reliably higher than on admission of the same patients that may be an indicator of growing phenomena of dystrophy and micronecroses in vitals, so the indices of LDG and CPK may show the degree of severity of polyorganic insufficiency and determine its prognosis.
authors.forename: V K
authors.initials: VK
authors.lastname: Ostrovskiĭ
authors.forename: S V
authors.initials: SV
authors.lastname: Makarov
authors.forename: P N
authors.initials: PN
authors.lastname: Rodionov
authors.forename: L N
authors.initials: LN
authors.lastname: Kochetkov
mesh_terms: D034841:Abdominal Cavity; D000208:Acute Disease; D015415:Biomarkers / Q000097:blood; D003106:Colon / Q000473:pathology*; D003402:Creatine Kinase / Q000097:blood*; D006801:Humans; D007421:Intestine, Small / Q000473:pathology*; D007770:L-Lactate Dehydrogenase / Q000097:blood*; D009336:Necrosis / Q000175:diagnosis; D010179:Pancreas / Q000473:pathology*; D013492:Suppuration / Q000175:diagnosis
chemical_list: D015415:Biomarkers; D007770:L-Lactate Dehydrogenase; D003402:Creatine Kinase