title: Dimensionality reduction for the quantitative evaluation of a smartphone-based Timed Up and Go test.
abstract: The Timed Up and Go is a clinical test to assess mobility in the elderly and in Parkinson's disease. Lately instrumented versions of the test are being considered, where inertial sensors assess motion. To improve the pervasiveness, ease of use, and cost, we consider a smartphone's accelerometer as the measurement system. Several parameters (usually highly correlated) can be computed from the signals recorded during the test. To avoid redundancy and obtain the features that are most sensitive to the locomotor performance, a dimensionality reduction was performed through principal component analysis (PCA). Forty-nine healthy subjects of different ages were tested. PCA was performed to extract new features (principal components) which are not redundant combinations of the original parameters and account for most of the data variability. They can be useful for exploratory analysis and outlier detection. Then, a reduced set of the original parameters was selected through correlation analysis with the principal components. This set could be recommended for studies based on healthy adults. The proposed procedure could be used as a first-level feature selection in classification studies (i.e. healthy-Parkinson's disease, fallers-non fallers) and could allow, in the future, a complete system for movement analysis to be incorporated in a smartphone.
authors.affiliation: Department of Electronics, Computer Science, and Systems, University of Bologna, Bologna 40136, Italy. luca.palmerini@unibo.it
authors.forename: Luca
authors.initials: L
authors.lastname: Palmerini
authors.forename: Sabato
authors.initials: S
authors.lastname: Mellone
authors.forename: Laura
authors.initials: L
authors.lastname: Rocchi
authors.forename: Lorenzo
authors.initials: L
authors.lastname: Chiari
mesh_terms: D000054:Acceleration; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000465:Algorithms; D040421:Cell Phone; D004867:Equipment Design; D006801:Humans; D008875:Middle Aged; D018670:Monitoring, Ambulatory / Q000379:methods*; D009038:Motion; D009068:Movement; D010300:Parkinson Disease / Q000503:physiopathology*; D025341:Principal Component Analysis; D015203:Reproducibility of Results; D013997:Time Factors