title: Bicyclo[4.4.0]decane oxygenated sesquiterpenes from Eryngium maritimum essential oil.
abstract: Investigation of the essential oil of the aerial parts of Eryngium maritimum L. from Corsica led to the isolation of one known sesquiterpene (1) and three new oxygenated sesquiterpenes with a muurolane or cadinane skeleton (2-4). Structure assignments of 4 βH -muurol-9-en-15-al (1), 4 βH -cadin-9-en-15-al (2), 4 βH -muurol-9-en-15-ol (3) and 4 βH -cadin-9-en-15-ol (4) were carried out by GC/MS (EI and CI) and comprehensive 1D and 2D NMR spectroscopy. Antibacterial activity of Eryngium maritimum L. oil and column chromatography fractions have been investigated for the first time. The oxygenated fraction, which contains the four sesquiterpenes, was efficient against Listeria monocytogenes and Echerichia coli.
authors.affiliation: Université de Corse, UMR CNRS 6134, Laboratoire Chimie des Produits Naturels, Corti, France.
authors.forename: Florent
authors.initials: F
authors.lastname: Darriet
authors.forename: Mourad
authors.initials: M
authors.lastname: Bendahou
authors.forename: Jean-Marie
authors.initials: JM
authors.lastname: Desjobert
authors.forename: Jean
authors.initials: J
authors.lastname: Costa
authors.forename: Alain
authors.initials: A
authors.lastname: Muselli
mesh_terms: D000473:Alkanes / Q000737:chemistry / Q000494:pharmacology; D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000494:pharmacology; D001643:Bridged Bicyclo Compounds / Q000737:chemistry / Q000494:pharmacology; D031049:Eryngium / Q000737:chemistry*; D004926:Escherichia coli / Q000187:drug effects; D005602:France; D008089:Listeria monocytogenes / Q000187:drug effects; D009822:Oils, Volatile / Q000737:chemistry* / Q000494:pharmacology; D035261:Plant Components, Aerial / Q000737:chemistry; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology; D012717:Sesquiterpenes / Q000737:chemistry* / Q000494:pharmacology
chemical_list: D000473:Alkanes; D000900:Anti-Bacterial Agents; D001643:Bridged Bicyclo Compounds; D009822:Oils, Volatile; D010936:Plant Extracts; D012717:Sesquiterpenes; C012867:decane