title: [Iridoid glycosides from buds of Jasminum officinale L. var. grandiflorum].
abstract: The study on the buds of Jasminum officinale L. var. grandiflorum was carried out to look for anti-HBV constituents. The isolation and purification were performed by HPLC and chromatography on silica gel, polyamide and Sephadex LH-20 column. The structures were elucidated on the basis of physicochemical properties and spectral analysis. Six iridoid glycosides were identified as jasgranoside B (1), 6-O-methy-catalpol (2), deacetyl asperulosidic acid (3), aucubin (4), 8-dehydroxy shanzhiside (5), and loganin (6). Jasgranoside B (1) is a new compound. Compounds 2-6 were isolated from Jasminum officinale L. var. grandiflorum for the first time.
authors.affiliation: Hebei Key Laboratory of Research and Development for Traditional Chinese Medicine, Institute of Chinese Materia Medica, Chengde Medical College, Chengde 067000, China. zhaoguiqin1971@sina.com.cn
authors.forename: Gui-qin
authors.initials: GQ
authors.lastname: Zhao
authors.forename: Zhi-feng
authors.initials: ZF
authors.lastname: Yin
authors.forename: Yu-cui
authors.initials: YC
authors.lastname: Liu
authors.forename: Hong-bo
authors.initials: HB
authors.lastname: Li
mesh_terms: D000998:Antiviral Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D035264:Flowers / Q000737:chemistry; D005960:Glucosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D056945:Hep G2 Cells; D006514:Hepatitis B Surface Antigens / Q000378:metabolism; D006515:Hepatitis B virus / Q000276:immunology; D006801:Humans; D020128:Inhibitory Concentration 50; D057888:Iridoid Glucosides / Q000737:chemistry / Q000302:isolation & purification; D057889:Iridoid Glycosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D039823:Iridoids / Q000737:chemistry / Q000302:isolation & purification; D031660:Jasminum / Q000737:chemistry*; D015394:Molecular Structure; D010946:Plants, Medicinal / Q000737:chemistry*
chemical_list: D000998:Antiviral Agents; D005960:Glucosides; D006514:Hepatitis B Surface Antigens; D057888:Iridoid Glucosides; D057889:Iridoid Glycosides; D039823:Iridoids; C581346:jasgranoside B; C006650:aucubin; C059516:loganin