title: A total synthesis of millingtonine A.
abstract: A total synthesis of millingtonine A, a diglycosylated alkaloid, has been accomplished. Millingtonine A possesses a unique racemic tricyclic core structure not known from any other natural or synthetic source until now. The synthesis features a key bond-forming radical Ueno-Stork cyclization to form the heterocyclic core.
authors.affiliation: Department of Chemistry, University of Cambridge , Lensfield Road, CB2 1EW Cambridge, UK.
authors.forename: Jens
authors.initials: J
authors.lastname: Wegner
authors.forename: Steven V
authors.initials: SV
authors.lastname: Ley
authors.forename: Andreas
authors.initials: A
authors.lastname: Kirschning
authors.forename: Anne-Lene
authors.initials: AL
authors.lastname: Hansen
authors.forename: Javier Montenegro
authors.initials: JM
authors.lastname: Garcia
authors.forename: Ian R
authors.initials: IR
authors.lastname: Baxendale
mesh_terms: D000470:Alkaloids / Q000138:chemical synthesis*; D003500:Cyclization; D005960:Glucosides / Q000138:chemical synthesis*; D006031:Glycosylation; D006575:Heterocyclic Compounds, 3-Ring / Q000138:chemical synthesis*; D015394:Molecular Structure; D011758:Pyrroles / Q000138:chemical synthesis
chemical_list: D000470:Alkaloids; D005960:Glucosides; D006575:Heterocyclic Compounds, 3-Ring; D011758:Pyrroles