title: Extraocular Sebaceous Carcinoma: A Report of 2 Cases.
abstract: Sebaceous carcinoma is a rare, aggressive adnexal tumor of unknown etiology; 75% of these tumors arise in the periocular region while 25% arise at extraocular sites. This cutaneous tumor is a diagnostic sign of Muir-Torre syndrome, a disorder associated with visceral malignancies and gene abnormalities. Patients with sebaceous carcinoma should therefore be carefully evaluated; a detailed personal and family history of cancer, a thorough physical examination, additional tests where appropriate, and close monitoring will all be required. We report 2 cases of extraocular sebaceous carcinoma and review the literature, focusing on the association between sebaceous carcinoma and Muir-Torre syndrome.
authors.affiliation: Servicio de Dermatología, Hospital General Universitario Gregorio Marañón, Madrid, España. Electronic address: deysycieza@gmail.com.
authors.forename: D E
authors.initials: DE
authors.lastname: Cieza-Díaz
authors.forename: N
authors.initials: N
authors.lastname: Cano-Martínez
authors.forename: L
authors.initials: L
authors.lastname: Barchino-Ortiz
authors.forename: I
authors.initials: I
authors.lastname: Longo-Imedio