title: Castleman's disease mimetizing pancreatic tumor.
abstract: BACKGROUND
  Angiofollicular lymph node hyperplasia or Castleman's disease is a rare clinical condition. Knowledge about etiology and physiopathology; and treatment management as well are yet to be defined. Unicentric presentation of this disease affecting single lymph nodes in the mediastinum seems to be the most common presentation. Castleman's disease localized in the pancreas topographic area that mimics a pancreatic neoplasm is an even more uncommon event, with available published data of less than 15 cases until now.
  
  
  METHODS
  We present a 64-year-old male patient with a six-month past history of asthenia, adynamia, and lack of general clinical conditions. Imaging studies showed a nodular hypoechoic mass in the pancreatic head. Enucleation of the lesion was performed. Histopathological study revealed unicentric form of Castleman's Disease.
  
  
  CONCLUSIONS
  Castleman's disease mimetizing pancreatic tumor is uncommon and it also curses with a difficult preoperative diagnosis. Surgery seems to be the best therapeutic alternative for this disease.
authors.affiliation: Division of Gastrointestinal Surgery, Department of Surgery, Federal University of São Paulo, Paulista School of Medicine, São Paulo, Brazil. apodaca@uol.com.br
authors.forename: Franz Robert
authors.initials: FR
authors.lastname: Apodaca-Torrez
authors.forename: Benedito Herani
authors.initials: BH
authors.lastname: Filho
authors.forename: Reinaldo Isaacs
authors.initials: RI
authors.lastname: Beron
authors.forename: Alberto
authors.initials: A
authors.lastname: Goldenberg
authors.forename: Suzan Menasce
authors.initials: SM
authors.lastname: Goldman
authors.forename: Edson José
authors.initials: EJ
authors.lastname: Lobo
mesh_terms: D018952:Antigens, CD34 / Q000032:analysis; D018801:CD2 Antigens / Q000032:analysis; D005871:Castleman Disease / Q000175:diagnosis* / Q000378:metabolism; D003937:Diagnosis, Differential; D006801:Humans; D007150:Immunohistochemistry; D017493:Leukocyte Common Antigens / Q000032:analysis; D008297:Male; D008875:Middle Aged; D010179:Pancreas / Q000737:chemistry / Q000473:pathology*; D010190:Pancreatic Neoplasms / Q000175:diagnosis* / Q000378:metabolism; D014057:Tomography, X-Ray Computed
chemical_list: D018952:Antigens, CD34; D018801:CD2 Antigens; D017493:Leukocyte Common Antigens