title: Two new compounds from marine-derived fungus Penicillium sp. F11.
abstract: Two new compounds, penicillone A (1) and penicillactam (2), were isolated together with 17 known compounds from a marine-derived fungus Penicillium sp. F11. The structures of the new compounds as well as a firstly literatural reported known compound (3) were assigned by spectroscopic methods including 1D/2D NMR and MS analysis techniques. Their cytotoxicities against HT1080, Cne2, and Bel7402 cell lines were also evaluated.
authors.affiliation: Medical College, Xiamen University, Xiamen, 361005, China.
authors.forename: Ping
authors.initials: P
authors.lastname: Zhuang
authors.forename: Xi-Xiang
authors.initials: XX
authors.lastname: Tang
authors.forename: Zhi-Wei
authors.initials: ZW
authors.lastname: Yi
authors.forename: Ying-Kun
authors.initials: YK
authors.lastname: Qiu
authors.forename: Zhen
authors.initials: Z
authors.lastname: Wu
mesh_terms: D000970:Antineoplastic Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004354:Drug Screening Assays, Antitumor; D006801:Humans; D008386:Marine Biology; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010407:Penicillium / Q000737:chemistry*; D011753:Pyrones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: D000970:Antineoplastic Agents; D011753:Pyrones; C571131:penicillactam; C571132:penicillone A