title: Organocatalytic enantioselective pyrazol-3-one addition to maleimides: reactivity and stereochemical course.
abstract: The enantioselective synthesis of pyrazol-3-ones has not been extensively studied in organic synthesis. Here in we report the first asymmetric addition of pyrazolones to maleimides catalyzed by bifunctional thiourea catalysts.
authors.affiliation: Department of Organic Chemistry A. Mangini, University of Bologna, Viale Risorgimento 4, 40136 Bologna, Italy.
authors.forename: Andrea
authors.initials: A
authors.lastname: Mazzanti
authors.forename: Teresa
authors.initials: T
authors.lastname: Calbet
authors.forename: Merce
authors.initials: M
authors.lastname: Font-Bardia
authors.forename: Albert
authors.initials: A
authors.lastname: Moyano
authors.forename: Ramon
authors.initials: R
authors.lastname: Rios
mesh_terms: D002384:Catalysis; D008301:Maleimides / Q000737:chemistry*; D015394:Molecular Structure; D011720:Pyrazoles / Q000737:chemistry*; D013237:Stereoisomerism; D013890:Thiourea / Q000737:chemistry
chemical_list: D008301:Maleimides; D011720:Pyrazoles; D013890:Thiourea