title: Cross-industry standard process for data mining is applicable to the lung cancer surgery domain, improving decision making as well as knowledge and quality management.
abstract: OBJECTIVE
  The aim of this study was to assess the applicability of knowledge discovery in database methodology, based upon data mining techniques, to the investigation of lung cancer surgery.
  
  
  METHODS
  According to CRISP 1.0 methodology, a data mining (DM) project was developed on a data warehouse containing records for 501 patients operated on for lung cancer with curative intention. The modelling technique was logistic regression.
  
  
  RESULTS
  The finally selected model presented the following values: sensitivity 9.68%, specificity 100%, global precision 94.02%, positive predictive value 100% and negative predictive value 93.98% for a cut-off point set at 0.5. A receiver operating characteristic (ROC) curve was constructed. The area under the curve (CI 95%) was 0.817 (0.740- 0.893) (p < 0.05). Statistical association with perioperative mortality was found for the following variables [odds ratio (CI 95%)]: age over 70 [2.3822 (1.0338-5.4891)], heart disease [2.4875 (1.0089-6.1334)], peripheral arterial disease [5.7705 (1.9296-17.2570)], pneumonectomy [3.6199 (1.4939-8.7715)] and length of surgery (min) [1.0067 (1.0008-1.0126)].
  
  
  CONCLUSIONS
  The CRISP-DM process model is very suitable for lung cancer surgery analysis, improving decision making as well as knowledge and quality management.
authors.affiliation: Thoracic Surgery Service, Vigo University Hospital, Vigo, Pontevedra, Spain. eduardorivo@yahoo.es
authors.forename: Eduardo
authors.initials: E
authors.lastname: Rivo
authors.forename: Javier
authors.initials: J
authors.lastname: de la Fuente
authors.forename: Ángel
authors.initials: Á
authors.lastname: Rivo
authors.forename: Eva
authors.initials: E
authors.lastname: García-Fontán
authors.forename: Miguel-Ángel
authors.initials: MÁ
authors.lastname: Cañizares
authors.forename: Pedro
authors.initials: P
authors.lastname: Gil
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D057225:Data Mining; D003657:Decision Making; D005260:Female; D006801:Humans; D019359:Knowledge; D016015:Logistic Models; D008175:Lung Neoplasms / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D008962:Models, Theoretical; D011237:Predictive Value of Tests; D013510:Pulmonary Surgical Procedures; D011787:Quality of Health Care / Q000592:standards*; D012372:ROC Curve; D012307:Risk Factors