title: Regulation of lipid peroxidation in the retina under the effect of bright light.
abstract: Changes in LPO intensity under the effect of exposure to bright light and the possibility of their correction with antioxidants were studied on rabbits with diabetic retinopathy. It was found that enhanced LPO caused by exposure to bright light in rabbits with diabetic retinopathy can be corrected with antioxidants. Phenosan potassium salt, α-tocopherol, and oxypyridine were more effective than SOD and taurine in preventing MDA accumulation. A complex of natural and synthetic antioxidants was most efficient in correcting LPO under conditions of exposure to bright light.
authors.affiliation: Institute of Physics, Azerbaijanian National Academy of Sciences; Zafira Alieva National Center of Ophthalmology, Baku, Azerbaijan.
authors.forename: A I
authors.initials: AI
authors.lastname: Dzhafarov
authors.forename: E M
authors.initials: EM
authors.lastname: Kasimov
authors.forename: Sh Y
authors.initials: ShY
authors.lastname: Mamedov
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000008:administration & dosage / Q000494:pharmacology; D003930:Diabetic Retinopathy / Q000139:chemically induced; D004230:Dithizone / Q000008:administration & dosage / Q000494:pharmacology; D008027:Light / Q000009:adverse effects*; D015227:Lipid Peroxidation / Q000187:drug effects / Q000528:radiation effects*; D010640:Phenothiazines / Q000008:administration & dosage / Q000494:pharmacology; D011817:Rabbits; D012160:Retina / Q000187:drug effects / Q000528:radiation effects*; D013482:Superoxide Dismutase / Q000008:administration & dosage / Q000494:pharmacology; D013654:Taurine / Q000008:administration & dosage / Q000494:pharmacology; D024502:alpha-Tocopherol / Q000008:administration & dosage / Q000494:pharmacology
chemical_list: D000975:Antioxidants; D010640:Phenothiazines; D013654:Taurine; D004230:Dithizone; D013482:Superoxide Dismutase; C031637:phenothiazine; D024502:alpha-Tocopherol