title: Direct and indirect regulatory mechanisms in TH17 cell differentiation and functions.
abstract: T helper 17 (TH17) cells have well-described roles in autoimmune diseases. The immune modulations of development and function of TH17 have become a key issue. In this review, we summarize the recent findings regarding the direct and indirect signalling regulatory mechanisms of TH17 cells in the general mouse model of autoimmune diseases and other human diseases.
authors.affiliation: National Center for Biomedical Analysis, Army Center for Microbial Detection and Research, Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences-AMMS, Beijing, China.
authors.forename: Y
authors.initials: Y
authors.lastname: Bi
authors.forename: R
authors.initials: R
authors.lastname: Yang
mesh_terms: D000818:Animals; D002454:Cell Differentiation / Q000276:immunology*; D006801:Humans; D051379:Mice; D015398:Signal Transduction / Q000276:immunology*; D058504:Th17 Cells / Q000166:cytology* / Q000276:immunology*