title: [Experience of cytoflavin administration for treating acute carbon monoxide poisoning].
abstract: Results of an analysis of the efficiency of using cytoflavin, a drug possessing cytoprotective and antihypoxemic properties, in a group of 215 patients with a diagnosis of acute carbon monoxide poisoning in 2004-2010 are compared to analogous data for 215 patients with same diagnosis treated in 1999-2004 without cytoflavin administration. It is established that timely application of cytoflavin (against the standard treatment of CO poisoning) favored lower expressiveness of post-hypoxemic encephalopathythatis characteristic of the given pathology.
authors.forename: Iu V
authors.initials: IuV
authors.lastname: Zobnin
authors.forename: A G
authors.initials: AG
authors.lastname: Petrova
authors.forename: I P
authors.initials: IP
authors.lastname: Provado
authors.forename: V V
authors.initials: VV
authors.lastname: Afanas'ev
mesh_terms: D000328:Adult; D002248:Carbon Monoxide / Q000009:adverse effects*; D002249:Carbon Monoxide Poisoning / Q000150:complications / Q000188:drug therapy* / Q000401:mortality / Q000503:physiopathology; D002263:Carboxyhemoglobin / Q000032:analysis / Q000037:antagonists & inhibitors* / Q000378:metabolism; D016022:Case-Control Studies; D004334:Drug Administration Schedule; D004338:Drug Combinations; D005260:Female; D005486:Flavin Mononucleotide / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D000860:Hypoxia / Q000150:complications / Q000188:drug therapy* / Q000401:mortality / Q000503:physiopathology; D007262:Infusions, Intravenous; D007290:Inosine Diphosphate / Q000008:administration & dosage / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D018696:Neuroprotective Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D009536:Niacinamide / Q000008:administration & dosage / Q000627:therapeutic use*; D012189:Retrospective Studies; D012426:Russia; D012720:Severity of Illness Index; D013386:Succinates / Q000008:administration & dosage / Q000627:therapeutic use*; D015996:Survival Rate; D014474:Unconsciousness / Q000517:prevention & control*
chemical_list: D004338:Drug Combinations; D018696:Neuroprotective Agents; D013386:Succinates; C507879:cytoflavin; D009536:Niacinamide; D005486:Flavin Mononucleotide; D002248:Carbon Monoxide; D007290:Inosine Diphosphate; D002263:Carboxyhemoglobin