title: Bioconjugated silicon quantum dots from one-step green synthesis.
abstract: Biofunctionalized silicon quantum dots were prepared through a one step strategy avoiding the use of chemical precursors. UV-Vis spectroscopy, Raman spectroscopy and HAADF-STEM prove oligonucleotide conjugation to the surface of silicon nanoparticle with an average size of 4 nm. The nanoparticle size results from the size-quenching effect during in situ conjugation. Photoemissive properties, conjugation efficiency and stability of these pure colloids were studied and demonstrate the bio-application potential, e.g. for nucleic acid vector delivery with semiconducting, biocompatible nanoparticles.
authors.affiliation: Department of Nanophysics, Istituto Italiano di Tecnologia, via Morego, 30, 16163 Genova, Italy. romuald.intartaglia@iit.it
authors.forename: Romuald
authors.initials: R
authors.lastname: Intartaglia
authors.forename: Annette
authors.initials: A
authors.lastname: Barchanski
authors.forename: Komal
authors.initials: K
authors.lastname: Bagga
authors.forename: Alessandro
authors.initials: A
authors.lastname: Genovese
authors.forename: Gobind
authors.initials: G
authors.lastname: Das
authors.forename: Philipp
authors.initials: P
authors.lastname: Wagener
authors.forename: Enzo
authors.initials: E
authors.lastname: Di Fabrizio
authors.forename: Alberto
authors.initials: A
authors.lastname: Diaspro
authors.forename: Fernando
authors.initials: F
authors.lastname: Brandi
authors.forename: Stephan
authors.initials: S
authors.lastname: Barcikowski
mesh_terms: D004247:DNA / Q000737:chemistry*; D055772:Green Chemistry Technology; D053758:Nanoparticles / Q000737:chemistry / Q000648:ultrastructure; D045663:Quantum Dots; D012825:Silicon / Q000737:chemistry*; D014466:Ultraviolet Rays
chemical_list: D004247:DNA; D012825:Silicon