title: Spectroscopic investigation of collagen scaffolds impregnated with AgNPs coated by PEG/TX-100 mixed systems.
abstract: Silver nanoparticles have received attention as novel antimicrobial agents due to their high surface area to volume ratio and the unique chemical and physical properties. In order to study the effects of capping agents on silver nanoparticles (AgNPs), the nanoparticles were synthesized via chemical reduction method using different concentrations (0.3 mM, 0.6 mM and 0.9 mM) of polyethylene glycol (PEG) and Triton X-100 (TX). Also, AgNPs capped by the combinations of both PEG and TX were synthesized. These coated AgNPs were incorporated into collagen, lyophilized to form scaffolds and characterized by FTIR and FT-Raman spectroscopy. Results on mechanical property of all the scaffolds displayed no significant difference in the percentage elongation at break. However, the maximum percentage of 46.67% was observed with the combinations (0.9 mM PEG+0.9 mM TX). This implies that the combinations of surfactants increase the elasticity, which is useful for biomedical applications, e.g., Heart-valve preparations.
authors.affiliation: Division of Biomedical Engineering, University of Saskatchewan, 51 Campus Drive, Saskatoon, SK S7N 5A4, Canada.
authors.forename: A
authors.initials: A
authors.lastname: Mandal
authors.forename: V
authors.initials: V
authors.lastname: Meda
authors.forename: W J
authors.initials: WJ
authors.lastname: Zhang
authors.forename: A K
authors.initials: AK
authors.lastname: Dalai
mesh_terms: D000818:Animals; D002214:Capsules; D002417:Cattle; D003094:Collagen / Q000737:chemistry*; D003487:Cyanoacrylates / Q000737:chemistry*; D053768:Metal Nanoparticles / Q000737:chemistry*; D011092:Polyethylene Glycols / Q000737:chemistry*; D012834:Silver / Q000737:chemistry*; D013057:Spectrum Analysis
chemical_list: D002214:Capsules; D003487:Cyanoacrylates; C558475:poly(ethylcyanoacrylate); C551282:polyethylene glycol monooctylphenyl ether; D012834:Silver; D011092:Polyethylene Glycols; D003094:Collagen