title: Different mechanisms of intensification of contractile activity in the proximal and distal portions of the duodenum in psychogenic stress in rabbits.
abstract: Psychogenic stress in rabbits induced by fixation of the animals to a frame was accompanied by an increase in contractile activity of the duodenum. Against the background of blockade of muscarinic and nicotinic cholinergic receptors and β(1)/β(2)-adrenoceptors this increase was observed in postpyloric portion, but not in the distal third of the duodenum. The increase in contractile activity was determined by the direct effect of the hormonal stress factor on smooth muscles in the first case and by the influence of circulating catecholamines on excitatory β-adrenoceptors of cholinergic neurons of the enteral nervous system in the second.
authors.affiliation: Laboratory of Digestion Physiology, Department of Physiology of Visceral Systems, Institute of Experimental Medicine, Northwestern Branch of the Russian Academy of Medical Sciences, St. Petersburg, Russia. vladovs2@gmail.com
authors.forename: V I
authors.initials: VI
authors.lastname: Ovsyannikov
authors.forename: T P
authors.initials: TP
authors.lastname: Berezina
mesh_terms: D058671:Adrenergic beta-1 Receptor Antagonists / Q000494:pharmacology; D058672:Adrenergic beta-2 Receptor Antagonists / Q000494:pharmacology; D000818:Animals; D002395:Catecholamines / Q000097:blood / Q000378:metabolism; D059329:Cholinergic Neurons; D004386:Duodenum / Q000378:metabolism / Q000502:physiology*; D017615:Enteric Nervous System; D009043:Motor Activity / Q000187:drug effects; D018727:Muscarinic Antagonists / Q000494:pharmacology; D009119:Muscle Contraction / Q000187:drug effects / Q000502:physiology*; D009130:Muscle, Smooth / Q000187:drug effects / Q000502:physiology; D018733:Nicotinic Antagonists / Q000494:pharmacology; D010528:Peristalsis / Q000187:drug effects / Q000502:physiology*; D011817:Rabbits; D018342:Receptors, Adrenergic, beta-1 / Q000187:drug effects / Q000502:physiology; D018343:Receptors, Adrenergic, beta-2 / Q000187:drug effects / Q000502:physiology; D011976:Receptors, Muscarinic / Q000378:metabolism; D011978:Receptors, Nicotinic / Q000378:metabolism; D013315:Stress, Psychological
chemical_list: D058671:Adrenergic beta-1 Receptor Antagonists; D058672:Adrenergic beta-2 Receptor Antagonists; D002395:Catecholamines; D018727:Muscarinic Antagonists; D018733:Nicotinic Antagonists; D018342:Receptors, Adrenergic, beta-1; D018343:Receptors, Adrenergic, beta-2; D011976:Receptors, Muscarinic; D011978:Receptors, Nicotinic