title: Economic evaluation of lifestyle interventions to treat overweight or obesity in children.
abstract: OBJECTIVE
  To estimate lifetime cost effectiveness of lifestyle interventions to treat overweight and obese children, from the UK National Health Service perspective.
  
  
  METHODS
  An adaptation of the National Heart Forum economic model to predict lifetime health service costs and outcomes of lifestyle interventions on obesity-related diseases.
  
  
  METHODS
  Hospital or community-based weight-management programmes.
  
  
  METHODS
  Hypothetical cohorts of overweight or obese children based on body mass data from the National Child Measurement Programme.
  
  
  METHODS
  Lifestyle interventions that have been compared with no or minimal intervention in randomized controlled trials (RCTs).
  
  
  METHODS
  Reduction in body mass index (BMI) standard deviation score (SDS), intervention resources/costs, lifetime treatment costs, obesity-related diseases and cost per life year gained.
  
  
  RESULTS
  Ten RCTs were identified by our search strategy. The median effect of interventions versus control from these 10 RCTs was a difference in BMI SDS of -0.13 at 12 months, but the range in effects among interventions was broad (0.04 to -0.60). Indicative costs per child of these interventions ranged from £108 to £662. For obese children aged 10-11 years, an intervention that resulted in a median reduction in BMI SDS at 12 months at a moderate cost of £400 increased life expectancy by 0.19 years and intervention costs were offset by subsequent undiscounted savings in treatment costs (net saving of £110 per child), though this saving did not emerge until the sixth or seventh decade of life. The discounted cost per life year gained was £13 589. Results were broadly similar for interventions aimed at children aged 4-5 years and which targeted both obese and overweight children. For more costly interventions, savings were less likely.
  
  
  CONCLUSIONS
  Interventions to treat childhood obesity are potentially cost effective although cost savings and health benefits may not appear until the sixth or seventh decade of life.
authors.affiliation: School of Social and Community Medicine, University of Bristol, Bristol, UK. william.hollingworth@bristol.ac.uk
authors.forename: W
authors.initials: W
authors.lastname: Hollingworth
authors.forename: J
authors.initials: J
authors.lastname: Hawkins
authors.forename: D A
authors.initials: DA
authors.lastname: Lawlor
authors.forename: M
authors.initials: M
authors.lastname: Brown
authors.forename: T
authors.initials: T
authors.lastname: Marsh
authors.forename: R R
authors.initials: RR
authors.lastname: Kipping
mesh_terms: D015992:Body Mass Index; D002648:Child; D002675:Child, Preschool; D003362:Cost-Benefit Analysis; D005260:Female; D006801:Humans; D008297:Male; D018803:Models, Economic; D009313:National Health Programs; D009765:Obesity / Q000191:economics; D050177:Overweight / Q000191:economics* / Q000453:epidemiology / Q000517:prevention & control / Q000628:therapy*; D016032:Randomized Controlled Trials as Topic; D040242:Risk Reduction Behavior; D006113:United Kingdom / Q000453:epidemiology