title: On the activation of calcium-dependent proteolysis in brain neurons of spontaneously hypertensive rats (SHR strain).
abstract: Females of spontaneously hypertensive (SHR strain) and normotensive rats (WKY strain and Wistar) received drinking water with normal (80 mg/liter) or reduced concentration of Ca(2+)(8 mg/liter). Activity of calcium-dependent calpain protease in neurons did not differ in 18-day-old rat pups born and suckled by these animals. Our results are consistent with published data on normal metabolism of SHR rats up to the age of 30 days.
authors.affiliation: Department of Molecular and Radiational Biophysics, B. P. Konstantinov Petersburg Nuclear Physics Institute, Gatchina, Leningrad region, Russia. vlad.v.zakharov@mail.ru
authors.forename: V V
authors.initials: VV
authors.lastname: Zakharov
authors.forename: Yu K
authors.initials: YK
authors.lastname: Abramova
authors.forename: M I
authors.initials: MI
authors.lastname: Mosevitsky
mesh_terms: D000818:Animals; D001921:Brain; D002118:Calcium / Q000008:administration & dosage / Q000378:metabolism*; D002136:Calcium, Dietary / Q000378:metabolism*; D002154:Calpain / Q000378:metabolism*; D005260:Female; D006973:Hypertension / Q000378:metabolism*; D032389:Myocytes, Smooth Muscle / Q000166:cytology* / Q000378:metabolism; D009474:Neurons; D059748:Proteolysis; D051381:Rats; D011918:Rats, Inbred SHR; D011921:Rats, Inbred WKY; D017208:Rats, Wistar
chemical_list: D002136:Calcium, Dietary; D002154:Calpain; D002118:Calcium