title: Alteration of autonomic blood pressure control during hemodialysis in peripheral vascular disease patients.
abstract: Blood pressure (BP) response to volume depletion induced by hemodialysis (HD) treatment may be important to understand the pathophysiology of the increased mortality in HD patients with vascular calcification. In the present study a comparison between end stage renal disease (ESRD) patients affected by peripheral vascular disease (PVD) and ESRD patients without PVD was performed. Continuous blood pressure was recorded at the beginning and at the end of HD. BP and heart rate variability (HRV) were analyzed to quantify the autonomic nervous system regulation of heart beat and peripheral resistance. PVD patients showed an increase of pulse pressure (PP) during HD, an altered autonomic peripheral control, a lower sympathetic activity, with respect to ESRD patients without PVD.
authors.affiliation: Politecnico di Milano, Department of Bioengineering, P zza Leonardo daVinci 32, 20133 Milano, Italy. jasmine.ion@mail.polimi.it
authors.forename: Jasmine Ion
authors.initials: JI
authors.lastname: Titapiccolo
authors.forename: Sergio
authors.initials: S
authors.lastname: Cerutti
authors.forename: Francesco
authors.initials: F
authors.lastname: Garzotto
authors.forename: Dinna
authors.initials: D
authors.lastname: Cruz
authors.forename: Ulrich
authors.initials: U
authors.lastname: Moissl
authors.forename: Ciro
authors.initials: C
authors.lastname: Tetta
authors.forename: Maria G
authors.initials: MG
authors.lastname: Signorini
authors.forename: Claudio
authors.initials: C
authors.lastname: Ronco
authors.forename: Manuela
authors.initials: M
authors.lastname: Ferrario
mesh_terms: D000222:Adaptation, Physiological; D000368:Aged; D001341:Autonomic Nervous System / Q000503:physiopathology*; D017704:Baroreflex; D001794:Blood Pressure; D025461:Feedback, Physiological; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications / Q000503:physiopathology* / Q000534:rehabilitation*; D008297:Male; D008875:Middle Aged; D016491:Peripheral Vascular Diseases / Q000150:complications / Q000503:physiopathology*; D006435:Renal Dialysis