title: Low density lipoprotein S-homocysteinylation is increased in acute myocardial infarction patients.
abstract: OBJECTIVE
  We have investigated on the levels of homocysteine linked to LDL in acute myocardial infarction patients.
  
  
  METHODS
  We used capillary electrophoresis to measure LDL-bound thiols in 16 AMI individuals and 32 healthy volunteers.
  
  
  RESULTS
  We found a significant increase of apo-B homocysteine and cysteine levels in LDL fraction of AMI subjects.
  
  
  CONCLUSIONS
  Our findings suggest that also LDL S-homocysteinylation may be considered among the markers for the CVD risk evaluation.
authors.affiliation: Department of Biomedical Sciences, University of Sassari, Porto Conte Ricerche Srl, Tramariglio, Alghero, Sassari, Italy. angelozinellu@libero.it
authors.forename: Angelo
authors.initials: A
authors.lastname: Zinellu
authors.forename: Salvatore
authors.initials: S
authors.lastname: Sotgia
authors.forename: Bastianina
authors.initials: B
authors.lastname: Scanu
authors.forename: Luca
authors.initials: L
authors.lastname: Deiana
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Talanas
authors.forename: PierFranco
authors.initials: P
authors.lastname: Terrosu
authors.forename: Ciriaco
authors.initials: C
authors.lastname: Carru
mesh_terms: D054058:Acute Coronary Syndrome / Q000097:blood; D000368:Aged; D001055:Apolipoproteins B / Q000097:blood / Q000737:chemistry; D015415:Biomarkers / Q000097:blood / Q000737:chemistry; D002318:Cardiovascular Diseases / Q000453:epidemiology; D003545:Cysteine / Q000097:blood / Q000737:chemistry; D019075:Electrophoresis, Capillary; D005260:Female; D006710:Homocysteine / Q000097:blood* / Q000737:chemistry*; D006801:Humans; D007558:Italy / Q000453:epidemiology; D008077:Lipoproteins, LDL / Q000097:blood* / Q000737:chemistry* / Q000302:isolation & purification; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000097:blood*; D012307:Risk Factors; D013438:Sulfhydryl Compounds / Q000097:blood / Q000737:chemistry
chemical_list: D001055:Apolipoproteins B; D015415:Biomarkers; D008077:Lipoproteins, LDL; D013438:Sulfhydryl Compounds; D006710:Homocysteine; D003545:Cysteine