title: Relationship of serum and saliva calcium, phosphorus and alkaline phosphatase with dry mouth feeling in menopause.
abstract: OBJECTIVE
  The aim of this study was to compare serum and saliva calcium, phosphorus and alkaline phosphatase of menopausal women with/without dry mouth (DM) feeling.
  
  
  BACKGROUND
  The composition of saliva in menopause women with/without DM feeling is different. Some of these differences are in hormones that are related to bone turnover.
  
  
  METHODS
  A case-control study was carried out on 60 selected menopausal women aged 45-79 years with or without DM feeling (30 as case, 30 as control), conducted at the Clinic of Oral Medicine, Tehran University of Medical Sciences. The phosphorus concentration was measured by photometrical measurement of the blue colour formed after the addition of ammonium molybdate and stannous chloride; calcium was measured by Arsenazo reaction; and alkaline phosphatase by the pNPP-AMP method. Statistical analysis of Student's t-test was used.
  
  
  RESULTS
  The mean serum phosphorus and alkaline phosphatase, stimulated and unstimulated saliva calcium and alkaline phosphatase levels were significantly higher in the menopausal women suffering from DM. There were no significant differences between groups regarding saliva phosphorus and serum calcium concentration.
  
  
  CONCLUSIONS
  Calcium, phosphorus and alkaline phosphatase appear associated with DM feeling in menopause.
authors.affiliation: Department of Oral Medicine, Dental Research Center, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran. aghahose@sina.tums.ac.ir
authors.forename: Farzaneh
authors.initials: F
authors.lastname: Agha-Hosseini
authors.forename: Iraj
authors.initials: I
authors.lastname: Mirzaii-Dizgah
authors.forename: Mahdieh-Sadat
authors.initials: MS
authors.lastname: Moosavi
mesh_terms: D000368:Aged; D000469:Alkaline Phosphatase / Q000032:analysis / Q000097:blood; D015415:Biomarkers / Q000032:analysis / Q000097:blood; D016723:Bone Remodeling / Q000502:physiology; D001842:Bone and Bones / Q000378:metabolism; D002118:Calcium / Q000032:analysis / Q000097:blood*; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D008593:Menopause / Q000097:blood* / Q000378:metabolism; D008875:Middle Aged; D010758:Phosphorus / Q000032:analysis / Q000097:blood*; D010783:Photometry; D012463:Saliva / Q000737:chemistry* / Q000201:enzymology; D013053:Spectrophotometry; D014987:Xerostomia / Q000097:blood* / Q000378:metabolism
chemical_list: D015415:Biomarkers; D010758:Phosphorus; D000469:Alkaline Phosphatase; D002118:Calcium