title: Gastric emptying in Billroth-I and Roux-en-Y reconstruction after distal gastrectomy using C-acetate breath test.
abstract: OBJECTIVE
  Billroth-I and Roux-en-Y procedures have been applied generally as reconstruction techniques after distal gastrectomy. There have been few reports regarding the physiological differences of these two procedures. We compared gastric emptying after Roux-en-Y procedure with the Billroth-I procedure using the 13C-acetate breath test.
  
  
  METHODS
  Eleven patients who underwent distal gastrectomy, using reconstruction procedures of Billroth- I (B-I group: n=7) and Roux-en-Y (R-Y group: n=6), and 4 healthy volunteers (Control group) were studied. After ingestion of 200mL of liquid diet labelled with 100mg 13C-acetate, breath samples were collected every 5-15 minutes for 3 hours. The analysis of 13C-acetate enrichment was measured using infrared spectrometer.
  
  
  RESULTS
  Mean breath-Tmax of B-I group (14.2min) and R-Y group (13.0min) were significantly shorter compared with that of the control group (42.5min). Mean breath-T1/2 of B-I group (76.8min) and R-Y group (80.2min) were significantly shorter compared with that of the control group (133.3min). Mean breath-Cmax of B-I group (60.1min) and R-Y group (59.3min) were significantly higher than that of the control group (27.6min).
  
  
  CONCLUSIONS
  13C-acetate breath test was useful to evaluate gastric emptying. There were no differences in gastric emptying for both Billroth-I and Roux-en-Y reconstruction.
authors.affiliation: Department of Surgery, The University of Tokushima, Tokushima, Japan.
authors.forename: Nobuhiro
authors.initials: N
authors.lastname: Kurita
authors.forename: Mitsuo
authors.initials: M
authors.lastname: Shimada
authors.forename: Tohru
authors.initials: T
authors.lastname: Utsunomiya
authors.forename: Takashi
authors.initials: T
authors.lastname: Iwata
authors.forename: Masanori
authors.initials: M
authors.lastname: Nishioka
authors.forename: Kozo
authors.initials: K
authors.lastname: Yoshikawa
authors.forename: Jun
authors.initials: J
authors.lastname: Higashijima
authors.forename: Tomohiko
authors.initials: T
authors.lastname: Miyatani
authors.forename: Motoya
authors.initials: M
authors.lastname: Chikakiyo
authors.forename: Toshihiro
authors.initials: T
authors.lastname: Nakao
mesh_terms: D000085:Acetates / Q000378:metabolism*; D000368:Aged; D000713:Anastomosis, Roux-en-Y; D001944:Breath Tests / Q000379:methods*; D002247:Carbon Isotopes; D005260:Female; D005743:Gastrectomy / Q000379:methods*; D005746:Gastric Emptying; D005763:Gastroenterostomy; D006801:Humans; D008297:Male; D008875:Middle Aged
chemical_list: D000085:Acetates; D002247:Carbon Isotopes