title: Dengue and haemophagocytic lymphohistiocytosis.
abstract: Dengue is characterized by biphasic fever, myalgia or arthralgia, rash, leukopenia, and lymphadenopathy. It is self-limiting, and dengue-associated haemophagocytic lymphohistiocytosis has been reported in fewer than 20 children worldwide. We report the case of a 4-y-old boy with dengue who continued to have fever for 30 days, with hepatomegaly, thrombocytopenia, and leukopenia. Bone marrow examination showed haemophagocytes. The child was treated with steroids, instead etoposide and oral cyclosporine.
authors.affiliation: Department of Pediatrics, B.J. Wadia Hospital for Children, Mumbai, India.
authors.forename: Muznah
authors.initials: M
authors.lastname: Kapdi
authors.forename: Ira
authors.initials: I
authors.lastname: Shah
mesh_terms: D001856:Bone Marrow Examination; D002675:Child, Preschool; D016572:Cyclosporine / Q000627:therapeutic use; D003715:Dengue / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D006529:Hepatomegaly / Q000821:virology; D006801:Humans; D007970:Leukopenia / Q000821:virology; D051359:Lymphohistiocytosis, Hemophagocytic / Q000175:diagnosis* / Q000188:drug therapy / Q000821:virology; D008297:Male; D013256:Steroids / Q000627:therapeutic use; D013921:Thrombocytopenia / Q000821:virology
chemical_list: D013256:Steroids; D016572:Cyclosporine