title: Dose reduction and image quality in CT angiography for cerebral aneurysm with various tube potentials and current settings.
abstract: OBJECTIVE
  The purpose of this study is to investigate the image quality on both axial and three-dimensional CT angiograms of the brain at various tube potentials and currents, and to propose the use of descriptors for evaluating the image quality of three-dimensional CT angiograms using entropy analysis.
  
  
  METHODS
  A head phantom was used as a target object. Axial CT and three-dimensional CT angiograms were obtained at various effective milliampere-second values (49-350 mAs) and tube potentials (80-140 kVp) with a 64-row detector CT scanner. Lens doses were measured using a planar silicon pin-photodiode system. The signal-to-noise ratio (SNR) and streak artefacts on the axial CT angiograms were evaluated and the image quality of the three-dimensional CT angiograms was assessed using entropy analysis.
  
  
  RESULTS
  Lens doses increased with tube potential and effective milliampere-seconds. From the evaluation of SNR and streak artefacts on axial CT angiograms, we found that the image quality was improved by setting the tube potential at 100 kVp. However, there was little visual difference in the image quality for 100 kVp between 252 (effective value recommended by the manufacturer) and 350 mAs (maximum effective value). In the entropy analysis of the image quality of three-dimensional CT angiograms, the mutual information (information gain) per lens dose was largest at 80 kVp and 252 mAs.
  
  
  CONCLUSIONS
  Our results suggested that the suitable tube potentials for axial CT and three-dimensional CT angiograms were 100 and 80 kVp, respectively, and the effective milliampere-second value recommended by the manufacturer was appropriate.
authors.affiliation: Department of Radiological Technology, Nagoya University School of Health Sciences, Nagoya, Japan. imai@met.nagoya-u.ac.jp
authors.forename: K
authors.initials: K
authors.lastname: Imai
authors.forename: M
authors.initials: M
authors.lastname: Ikeda
authors.forename: C
authors.initials: C
authors.lastname: Kawaura
authors.forename: T
authors.initials: T
authors.lastname: Aoyama
authors.forename: Y
authors.initials: Y
authors.lastname: Enchi
authors.forename: M
authors.initials: M
authors.lastname: Yamauchi
mesh_terms: D002533:Cerebral Angiography / Q000295:instrumentation / Q000379:methods*; D006801:Humans; D002532:Intracranial Aneurysm / Q000000981:diagnostic imaging*; D019047:Phantoms, Imaging; D011829:Radiation Dosage; D011835:Radiation Protection / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed / Q000379:methods*