title: Young's modulus measurement on pig trachea and bronchial airways.
abstract: Young's Modulus was measured on the trachea and first three generations of pig airways by compression. A simple and low-cost system for measuring the elastic properties of small bio-materials is presented. The force-displacement measurements have been undertaken on dissected cartilage and trachea mucosa from pig trachea and bronchial segments. Young's Modulus of trachea wall, 1.78 ± 0.51 MPa, is found to be dominated by the trachea cartilage of value 1.74 ± 0.85 MPa while the modulus for trachea mucosa was 0.15 ± 0.03 MPa. The Young's Modulus of the airway wall from the first three generations of bronchi decreases from 1.35 ± 0.17 to 0.35 ± 0.10 MPa which is also found to be dominated by the airway cartilage. Airway mucosa is found to have similar Young's modulus of 0.036 ± 0.005 MPa for the first three generations of bronchial airways.
authors.affiliation: Division of Engineering, King’s College London, Strand WC2R 2LS, UK. jauyi.wang@kcl.ac.uk
authors.forename: Jau-Yi
authors.initials: JY
authors.lastname: Wang
authors.forename: Patrick
authors.initials: P
authors.lastname: Mesquida
authors.forename: Tak
authors.initials: T
authors.lastname: Lee
mesh_terms: D000818:Animals; D001980:Bronchi / Q000502:physiology*; D003198:Computer Simulation; D055119:Elastic Modulus / Q000502:physiology*; D004867:Equipment Design; D019544:Equipment Failure Analysis; D006244:Hardness / Q000502:physiology; D006245:Hardness Tests / Q000295:instrumentation*; D008954:Models, Biological; D010812:Physical Stimulation / Q000295:instrumentation*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013552:Swine; D014132:Trachea / Q000502:physiology*