title: Automated high-performance cIMT measurement techniques using patented AtheroEdge™: a screening and home monitoring system.
abstract: The evaluation of the carotid artery wall is fundamental for the assessment of cardiovascular risk. This paper presents the general architecture of an automatic strategy, which segments the lumen-intima and media-adventitia borders, classified under a class of Patented AtheroEdge™ systems (Global Biomedical Technologies, Inc, CA, USA). Guidelines to produce accurate and repeatable measurements of the intima-media thickness are provided and the problem of the different distance metrics one can adopt is confronted. We compared the results of a completely automatic algorithm that we developed with those of a semi-automatic algorithm, and showed final segmentation results for both techniques. The overall rationale is to provide user-independent high-performance techniques suitable for screening and remote monitoring.
authors.affiliation: Biolab, Department of Electronics, Politecnico di Torino, 10129 Torino, Italy. filippo.molinari@polito.it
authors.forename: Filippo
authors.initials: F
authors.lastname: Molinari
authors.forename: Kristen M
authors.initials: KM
authors.lastname: Meiburger
authors.forename: Jasjit
authors.initials: J
authors.lastname: Suri
mesh_terms: D000465:Algorithms; D001158:Arteries / Q000473:pathology; D001331:Automation; D002309:Cardiology / Q000379:methods; D002318:Cardiovascular Diseases / Q000473:pathology; D002340:Carotid Artery Diseases / Q000473:pathology; D059168:Carotid Intima-Media Thickness; D016208:Databases, Factual; D001330:Electronic Data Processing; D004867:Equipment Design; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D018670:Monitoring, Ambulatory / Q000379:methods*; D015203:Reproducibility of Results; D012306:Risk