title: Intracranial stenting as monotherapy in subarachnoid hemorrhage and sickle cell disease.
abstract: BACKGROUND
  Although there have been a few reports of coiling intracranial aneurysms in patients with sickle cell disease (SCD), there are no reports of intracranial stent placement in this patient population. A patient in whom stent placement was utilized as monotherapy to treat a blister-like aneurysm is described and the implications of SCD and endovascular treatment are discussed.
  
  
  METHODS
  A 37-year-old man with SCD presented with diffuse subarachnoid hemorrhage. Angiography confirmed a 2 mm irregular aneurysm on the posterior cerebral artery which was treated with an oversized Neuroform 3 stent that was placed across the aneurysm neck by the senior author (KRB). Follow-up CT angiography showed no residual aneurysmal filling. The patient was discharged home in a stable condition, and he continues to do well 4 weeks following the procedure with no recurrence of the aneurysm.
  
  
  CONCLUSIONS
  This report reviews hypercoagulability in SCD and the treatment options for intracranial aneurysms in patients with SCD. Additionally, the reported case suggests that intracranial stent placement may be a viable option for treating complex intracranial aneurysms in SCD patients.
authors.affiliation: Yale University School of Medicine, New Haven, Connecticut, USA.
authors.forename: Asiri
authors.initials: A
authors.lastname: Ediriwickrema
authors.forename: Theresa
authors.initials: T
authors.lastname: Williamson
authors.forename: Ryan
authors.initials: R
authors.lastname: Hebert
authors.forename: Charles
authors.initials: C
authors.lastname: Matouk
authors.forename: Michele H
authors.initials: MH
authors.lastname: Johnson
authors.forename: Ketan R
authors.initials: KR
authors.lastname: Bulsara
mesh_terms: D000328:Adult; D000755:Anemia, Sickle Cell / Q000150:complications / Q000000981:diagnostic imaging* / Q000601:surgery; D006801:Humans; D002532:Intracranial Aneurysm / Q000150:complications / Q000000981:diagnostic imaging* / Q000601:surgery; D008297:Male; D011859:Radiography; D015607:Stents; D013345:Subarachnoid Hemorrhage / Q000150:complications / Q000000981:diagnostic imaging* / Q000601:surgery; D016896:Treatment Outcome