title: Cognitive functions before and 1 year after surgical and endovascular treatment in patients with unruptured intracranial aneurysms.
abstract: OBJECTIVE
  This prospective study investigated whether surgery or endovascular treatment for unruptured intracranial aneurysms (UIAs) affects cognitive functions.
  
  
  METHODS
  Four neuropsychological variables from an Auditory Verbal Learning Test (overall capacity of verbal memory and delayed recall) and a Trail Making Test (psychomotor speed and cognitive flexibility) were investigated before and 1 year after treatment for UIAs in 65 patients < 61 years of age. This cohort consists of 15 men and 50 women aged 15-60 (mean age 44.9) years.
  
  
  RESULTS
  Group-rate analysis showed a non-significant increase in post-treatment scores in the four neuropsychological variables. In addition, no significant differences were found between the surgical clipping (SC) and endovascular coiling (EC) group. Event-rate analysis demonstrated that two patients from the EC and one from the SC group developed cognitive impairment after treatment.
  
  
  CONCLUSIONS
  Surgical and endovascular repair for UIAs do not impair cognition in patients without postoperative restrictions in lifestyle.
authors.affiliation: Prague Psychiatric Center, Ústavní 91, Prague 8- Bohnice, Czech Republic, University of New York in Prague, Czech Republic.
authors.forename: Marek
authors.initials: M
authors.lastname: Preiss
authors.forename: David
authors.initials: D
authors.lastname: Netuka
authors.forename: Jana
authors.initials: J
authors.lastname: Koblihová
authors.forename: Lenka
authors.initials: L
authors.lastname: Bernardová
authors.forename: František
authors.initials: F
authors.lastname: Charvát
authors.forename: Vladimír
authors.initials: V
authors.lastname: Beneš
mesh_terms: D000293:Adolescent; D000328:Adult; D003072:Cognition Disorders / Q000209:etiology*; D057510:Endovascular Procedures / Q000379:methods*; D005260:Female; D006801:Humans; D002532:Intracranial Aneurysm / Q000523:psychology* / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D011182:Postoperative Care; D011300:Preoperative Care; D011446:Prospective Studies; D011596:Psychomotor Disorders / Q000209:etiology; D055815:Young Adult