title: Immunotoxicity of tannery effluent to the freshwater fish Cyprinous carpio.
abstract: This study was undertaken to determine the effect of chronic exposure to sub-lethal concentrations of tannery effluent (TE) on the humoral antibody response and the cell-mediated immune response of the fish Cyprinous carpio. The LC(50) value of the TE for C. carpio was determined by bioassay to be 3.8%. Sub-lethal concentrations of TE (0.6% and 0.3%) significantly suppressed the humoral and cell-mediated immune responses. Exposure of C. carpio to the TE had a significant effect on mean acceptance time (MAT) for transplanted scales. MAT was found to be 5-8 days for autografts and 4-7 days for allografts. The somatic indices of the kidney and spleen were reduced compared with controls.
authors.affiliation: Sri Paramakalyani Centre of Excellence in Environmental Sciences, Manonmaniam Sundaranar University, Alwarkurichi, Tamil Nadu, 627 412, India. agmspkce@rediffmail.com
authors.forename: A G
authors.initials: AG
authors.lastname: Murugesan
authors.forename: A
authors.initials: A
authors.lastname: Ramathilaga
authors.forename: J K
authors.initials: JK
authors.lastname: Samson Ponselvan
authors.forename: R
authors.initials: R
authors.lastname: Dinagaran Michael
mesh_terms: D000818:Animals; D002347:Carps; D004784:Environmental Monitoring; D005618:Fresh Water / Q000737:chemistry; D007107:Immune System / Q000187:drug effects; D007111:Immunity, Cellular / Q000187:drug effects; D000922:Immunotoxins / Q000633:toxicity*; D007220:Industrial Waste / Q000032:analysis*; D013633:Tanning; D014874:Water Pollutants, Chemical / Q000032:analysis / Q000633:toxicity*
chemical_list: D000922:Immunotoxins; D007220:Industrial Waste; D014874:Water Pollutants, Chemical