title: Design of N-cinnamyl sulfinamides as new sulfur-containing olefin ligands for asymmetric catalysis: achieving structural simplicity with a categorical linear framework.
abstract: The design and development of an extraordinarily interesting new class of chiral sulfur-olefin hybrid ligands with remarkable structural simplicity were described. These unique sulfinamide-olefin ligands have been proved to be highly effective ligands in rhodium-catalyzed asymmetric 1,4-addition reactions of aryl boronic acids to α,β-unsaturated carbonyl compounds (up to 99% yield and 98% ee).
authors.affiliation: Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai, 201203, People's Republic of China.
authors.forename: Shen-Shuang
authors.initials: SS
authors.lastname: Jin
authors.forename: Hui
authors.initials: H
authors.lastname: Wang
authors.forename: Ting-Shun
authors.initials: TS
authors.lastname: Zhu
authors.forename: Ming-Hua
authors.initials: MH
authors.lastname: Xu
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D000577:Amides / Q000737:chemistry*; D002384:Catalysis; D002934:Cinnamates / Q000737:chemistry*; D008024:Ligands; D015394:Molecular Structure; D013237:Stereoisomerism; D013455:Sulfur / Q000737:chemistry*
chemical_list: D000475:Alkenes; D000577:Amides; D002934:Cinnamates; D008024:Ligands; D013455:Sulfur