title: Anti-bacterial treatment of polyethylene by cold plasma for medical purposes.
abstract: Polyethylene (PE) is one of the most widely used polymers in many industrial applications. Biomedical uses seem to be attractive, with increasing interest. However, PE it prone to infections and its additional surface treatment is indispensable. An increase in resistance to infections can be achieved by treating PE surfaces with substances containing antibacterial groups such as triclosan (5-Chloro-2-(2,4-dichlorophenoxy)phenol) and chlorhexidine (1,1'-Hexamethylenebis[5-(4-chlorophenyl)biguanide]). This work has examined the impact of selected antibacterial substances immobilized on low-density polyethylene (LDPE) via polyacrylic acid (PAA) grafted on LDPE by low-temperature barrier discharge plasma. This LDPE surface treatment led to inhibition of Escherichia coli and Staphylococcus aureus adhesion; the first causes intestinal disease, peritonitis, mastitis, pneumonia, septicemia, the latter is the reason for wound and urinary tract infections.
authors.affiliation: Polymer Institute, Slovak Academy of Sciences, Dúbravská cesta 9, 845 41 Bratislava 45, Slovakia.
authors.forename: Anton
authors.initials: A
authors.lastname: Popelka
authors.forename: Igor
authors.initials: I
authors.lastname: Novák
authors.forename: Marián
authors.initials: M
authors.lastname: Lehocký
authors.forename: Ivan
authors.initials: I
authors.lastname: Chodák
authors.forename: Ján
authors.initials: J
authors.lastname: Sedliačik
authors.forename: Milada
authors.initials: M
authors.lastname: Gajtanska
authors.forename: Mariana
authors.initials: M
authors.lastname: Sedliačiková
authors.forename: Alenka
authors.initials: A
authors.lastname: Vesel
authors.forename: Ita
authors.initials: I
authors.lastname: Junkar
authors.forename: Angela
authors.initials: A
authors.lastname: Kleinová
authors.forename: Milena
authors.initials: M
authors.lastname: Spírková
authors.forename: František
authors.initials: F
authors.lastname: Bílek
mesh_terms: D000180:Acrylic Resins / Q000737:chemistry; D000900:Anti-Bacterial Agents / Q000737:chemistry*; D001422:Bacterial Adhesion / Q000187:drug effects*; D001672:Biocompatible Materials / Q000138:chemical synthesis*; D002710:Chlorhexidine / Q000737:chemistry; D003432:Cross-Linking Reagents / Q000737:chemistry; D004926:Escherichia coli / Q000187:drug effects; D005976:Glutaral / Q000737:chemistry; D008826:Microbial Sensitivity Tests; D018625:Microscopy, Atomic Force; D058626:Plasma Gases / Q000737:chemistry*; D020959:Polyethylene / Q000737:chemistry*; D017550:Spectroscopy, Fourier Transform Infrared; D013211:Staphylococcus aureus / Q000187:drug effects; D013499:Surface Properties; D013816:Thermodynamics; D014260:Triclosan / Q000737:chemistry; D017155:Wettability
chemical_list: D000180:Acrylic Resins; D000900:Anti-Bacterial Agents; D001672:Biocompatible Materials; D003432:Cross-Linking Reagents; D058626:Plasma Gases; D014260:Triclosan; C006903:carbopol 940; D020959:Polyethylene; D002710:Chlorhexidine; D005976:Glutaral