title: [Restless legs syndrome - a review].
abstract: Restless legs syndrome (RLS) is a common disorder with a prevalence between 10-20% in Iceland. There are two forms of RLS, idiopathic and secondary. Symptom onset of RLS before the age of 45 suggests an idiopathic form with no known underlying cause but inheritance. Symptom onset after age of 45 indicates a secondary form with an underlying cause without inheritance. Causes for secondary forms are for example: iron depletion, uraemia and polyneuropathy. Symptoms of RLS are uncomfortable and unpleasant deep sensations in the legs that are felt at rest, accompanied by an urge to move the legs, typically just before sleep. Accompanying RLS is a sleep disturbance that can lead to daytime somnolence, decreased quality of life, poor concentration, memory problems, depression and decreased energy. Dopamine agonists are currently the first line treatment for RLS.
  
  
  
  restless legs, periodic limb movements, sleep disturbance, dopamine agonists.
authors.affiliation: Department of Neurology Karolinska Hospital, Stockholm, Sweden. olafur.sveinsson@karolinska.se
authors.forename: Olafur Arni
authors.initials: OA
authors.lastname: Sveinsson
authors.forename: Albert Pall
authors.initials: AP
authors.lastname: Sigurdsson
mesh_terms: D000328:Adult; D017668:Age of Onset; D018491:Dopamine Agonists / Q000627:therapeutic use; D006801:Humans; D007055:Iceland / Q000453:epidemiology; D008875:Middle Aged; D015995:Prevalence; D011379:Prognosis; D012148:Restless Legs Syndrome / Q000150:complications / Q000188:drug therapy / Q000453:epidemiology; D012307:Risk Factors
chemical_list: D018491:Dopamine Agonists