title: Evaluation of the chronic obstructive pulmonary disease assessment test for measurement of health-related quality of life in patients with interstitial lung disease.
abstract: OBJECTIVE
  A well-validated instrument that is simple to use is needed to assess health-related quality of life in patients with interstitial lung disease (ILD). The COPD assessment test (CAT) is a recently introduced, short and simple questionnaire for COPD patients, which shows good and valid measurement properties. This study was conducted to evaluate the validity of the CAT in patients with ILD.
  
  
  METHODS
  Patients with ILD (n = 55) completed the CAT and the St. George's Respiratory Questionnaire (SGRQ). These patients also completed the Medical Research Council (MRC) dyspnoea scale, the Leicester Cough Questionnaire (LCQ), and the hospital anxiety and depression scale; performed 6-min walk tests and pulmonary function tests; and provided samples for arterial blood gas analysis.
  
  
  RESULTS
  There was a very strong correlation between the CAT score and the SGRQ total score (r = 0.93, P < 0.0001). The CAT score was also significantly correlated with the SGRQ symptoms score (r = 0.74, P < 0.0001), the SGRQ activity score (r = 0.87, P < 0.0001) and the SGRQ impact score (r = 0.89, P < 0.0001). Stepwise multiple regression analysis demonstrated that the MRC and LCQ scores contributed most to both the CAT score and the SGRQ total score.
  
  
  CONCLUSIONS
  The CAT is a short and simple questionnaire that shows good and valid measurement properties for assessing the health status of patients with ILD.
authors.affiliation: Department of Respiratory Medicine, Kobe City Medical Center General Hospital, Kobe, Japan. kazuma_n1101@yahoo.co.jp
authors.forename: Kazuma
authors.initials: K
authors.lastname: Nagata
authors.forename: Keisuke
authors.initials: K
authors.lastname: Tomii
authors.forename: Kojiro
authors.initials: K
authors.lastname: Otsuka
authors.forename: Ryo
authors.initials: R
authors.lastname: Tachikawa
authors.forename: Kyoko
authors.initials: K
authors.lastname: Otsuka
authors.forename: Junpei
authors.initials: J
authors.lastname: Takeshita
authors.forename: Kosuke
authors.initials: K
authors.lastname: Tanaka
authors.forename: Takeshi
authors.initials: T
authors.lastname: Matsumoto
authors.forename: Kazuya
authors.initials: K
authors.lastname: Monden
mesh_terms: D000368:Aged; D001007:Anxiety / Q000175:diagnosis; D003863:Depression / Q000175:diagnosis; D004417:Dyspnea / Q000503:physiopathology; D005260:Female; D006801:Humans; D017563:Lung Diseases, Interstitial / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D011581:Psychological Tests; D029424:Pulmonary Disease, Chronic Obstructive / Q000503:physiopathology*; D011658:Pulmonary Fibrosis / Q000503:physiopathology; D011788:Quality of Life; D015203:Reproducibility of Results; D012129:Respiratory Function Tests; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires