title: [Study on liver protection, cholagogic effect and hepatotoxicity of Gardeniae fructus].
abstract: Gardenia is widely used in clinical treatment to cure acute and chronic liver disease. But in recent two decades, hepatotoxicity has been reported from gardenia and major components. Based on literature research, the liver protection, cholagogic effect and hepatotoxicity have been discussed in-depth, with the purpose to provide a reference for rational usage in clinical and new drug development of gardenia.
authors.affiliation: Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, China. haiyansl@163.com
authors.forename: Haiyan
authors.initials: H
authors.lastname: Zhang
authors.forename: Weikui
authors.initials: W
authors.lastname: Wu
authors.forename: Fang
authors.initials: F
authors.lastname: Li
authors.forename: Wei
authors.initials: W
authors.lastname: Song
authors.forename: Ya
authors.initials: Y
authors.lastname: He
authors.forename: Ming
authors.initials: M
authors.lastname: Yang
mesh_terms: D000818:Animals; D004365:Drugs, Chinese Herbal / Q000494:pharmacology* / Q000633:toxicity; D005638:Fruit / Q000737:chemistry; D005704:Gallbladder / Q000187:drug effects*; D032062:Gardenia / Q000737:chemistry*; D006801:Humans; D008099:Liver / Q000187:drug effects*; D020011:Protective Agents / Q000494:pharmacology* / Q000633:toxicity
chemical_list: D004365:Drugs, Chinese Herbal; D020011:Protective Agents