title: Role of ribose deficit in rat testicular metabolism under conditions of overtraining.
abstract: Acute disorders of purine metabolism develop in rat testes under conditions of overtraining. These disorders are characterized by enhanced catabolism and reduced reutilization of purine mononucleotides and activation of lipid peroxidation of membrane structures against the background of reduced activities of the pentose cycle and antioxidant system. Administration of D-ribose to rats subjected to overtraining improves purine reutilization, stimulates the pentose cycle work, inhibits lipid peroxidation in membrane structures of the testes, and saves the testicular incretory function.
authors.affiliation: Department of Chemistry, Omsk State Agrarian University, Omsk, Russia.
authors.forename: V D
authors.initials: VD
authors.lastname: Conway
authors.forename: B A
authors.initials: BA
authors.lastname: Race
authors.forename: E A
authors.initials: EA
authors.lastname: Chigrinskiy
mesh_terms: D020155:3-Hydroxybutyric Acid / Q000097:blood; D000818:Animals; D000975:Antioxidants / Q000378:metabolism; D006019:Glycolysis / Q000502:physiology; D019344:Lactic Acid / Q000097:blood; D015227:Lipid Peroxidation; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D010805:Physical Conditioning, Animal; D011687:Purines / Q000378:metabolism; D051381:Rats; D017208:Rats, Wistar; D012266:Ribose / Q000008:administration & dosage / Q000172:deficiency / Q000378:metabolism; D013737:Testis / Q000378:metabolism*; D013739:Testosterone / Q000097:blood; D014527:Uric Acid / Q000097:blood
chemical_list: D000975:Antioxidants; D011687:Purines; D014527:Uric Acid; D019344:Lactic Acid; D013739:Testosterone; D012266:Ribose; D007986:Luteinizing Hormone; D020155:3-Hydroxybutyric Acid