title: The formation of P particle increased immunogenicity of norovirus P protein.
abstract: As a commentary on a recently published paper in Immunology, this article summaries the principle of norovirus P particle as a promising vaccine against noroviruses. It emphasizes the importance of P particle formation in the immune enhancement of the vaccine and methods for production/verification of high quality P particles which may be easily neglected by researchers.
authors.affiliation: Division of Infectious Diseases, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA. ming.tan@cchmc.org
authors.forename: Ming
authors.initials: M
authors.lastname: Tan
authors.forename: Xi
authors.initials: X
authors.lastname: Jiang
mesh_terms: D000818:Animals; D017250:Caliciviridae Infections / Q000276:immunology*; D005260:Female; D005759:Gastroenteritis / Q000276:immunology*; D006801:Humans; D029322:Norovirus / Q000276:immunology*; D058425:Vaccines, Virus-Like Particle / Q000276:immunology*
chemical_list: D058425:Vaccines, Virus-Like Particle