title: Mucositis, peri-implantitis, implant success, and survival of implants in patients with treated generalized aggressive periodontitis: 3- to 16-year results of a prospective long-term cohort study.
abstract: BACKGROUND
  The aim of this prospective study is to evaluate the prevalence of mucositis, peri-implantitis, implant success, and survival in partially edentulous patients treated for generalized aggressive periodontitis (GAgP) and in periodontally healthy individuals.
  
  
  METHODS
  Thirty-five patients treated for GAgP and 18 periodontally healthy patients orally rehabilitated with osseointegrated implants participated in the study. They were first examined 2 to 4 weeks before extraction of the non-retainable teeth (baseline) and 3 weeks after insertion of the final abutments. Additional examinations were performed during a 3-month recall schedule over a 5- to 16-year period (mean, 8.25 years). At every session, clinical parameters were recorded. At 1, 3, 5, 10, and 15 years after insertion of the superstructure, a microbiological and radiographic examination was performed.
  
  
  RESULTS
  The results show implant survival rates of 100% in periodontally healthy individuals versus 96% in GAgP patients. The implant success rate was 33% in GAgP patients and 50% in periodontally healthy individuals. In GAgP patients, mucositis was present in 56% and peri-implantitis in 26% of the implants. In periodontally healthy individuals, 40% of the implants showed mucositis and 10% peri-implantitis. GAgP patients had a five times greater risk of implant failure, a three times greater risk of mucositis, and a 14 times greater risk of peri-implantitis.
  
  
  CONCLUSIONS
  These results suggest that patients with treated GAgP are more susceptible to mucositis and peri-implantitis, with lower implant survival and success rates.
authors.affiliation: Department of Prosthetic Dentistry, Dental School of Medicine, Philipps University, Marburg/Lahn, Germany.
authors.forename: Katrin
authors.initials: K
authors.lastname: Swierkot
authors.forename: Peer
authors.initials: P
authors.lastname: Lottholz
authors.forename: Lavin
authors.initials: L
authors.lastname: Flores-de-Jacoby
authors.forename: Reiner
authors.initials: R
authors.lastname: Mengel
mesh_terms: D000328:Adult; D010520:Aggressive Periodontitis / Q000150:complications / Q000628:therapy; D016301:Alveolar Bone Loss / Q000000981:diagnostic imaging; D000704:Analysis of Variance; D001861:Bone Regeneration; D016022:Case-Control Studies; D015331:Cohort Studies; D003758:Dental Implantation, Endosseous / Q000009:adverse effects; D015921:Dental Implants / Q000009:adverse effects; D003773:Dental Plaque / Q000382:microbiology; D019094:Dental Prosthesis, Implant-Supported; D019232:Dental Restoration Failure; D005260:Female; D005500:Follow-Up Studies; D048091:Guided Tissue Regeneration; D006801:Humans; D007576:Jaw, Edentulous, Partially / Q000150:complications / Q000534:rehabilitation; D053208:Kaplan-Meier Estimate; D008297:Male; D008875:Middle Aged; D052016:Mucositis / Q000209:etiology*; D057873:Peri-Implantitis / Q000209:etiology*; D011446:Prospective Studies; D011859:Radiography; D012044:Regression Analysis; D012307:Risk Factors; D013280:Stomatitis / Q000209:etiology*
chemical_list: D015921:Dental Implants