title: Restoring the 3D vestibulo-ocular reflex via electrical stimulation: the Johns Hopkins multichannel vestibular prosthesis project.
abstract: Bilateral loss of vestibular sensation causes difficulty maintaining stable vision, posture and gait. An implantable prosthesis that partly restores normal activity on branches of the vestibular nerve should improve quality of life for individuals disabled by this disorder. We have developed a head-mounted multichannel vestibular prosthesis that restores sufficient semicircular canal function to partially recreate a normal 3-dimensional angular vestibulo-ocular reflex in animals. Here we describe several parallel lines of investigation directed toward refinement of this approach toward eventual clinical application.
authors.affiliation: Departments of Otolaryngology-Head & Neck Surgery, Johns Hopkins School of Medicine, Baltimore, MD, USA.
authors.forename: Mehdi A
authors.initials: MA
authors.lastname: Rahman
authors.forename: Chenkai
authors.initials: C
authors.lastname: Dai
authors.forename: Gene Y
authors.initials: GY
authors.lastname: Fridman
authors.forename: Natan S
authors.initials: NS
authors.lastname: Davidovics
authors.forename: Bryce
authors.initials: B
authors.lastname: Chiang
authors.forename: JoongHo
authors.initials: J
authors.lastname: Ahn
authors.forename: Russell
authors.initials: R
authors.lastname: Hayden
authors.forename: Thuy-Anh N
authors.initials: TA
authors.lastname: Melvin
authors.forename: Daniel Q
authors.initials: DQ
authors.lastname: Sun
authors.forename: Abderrahmane
authors.initials: A
authors.lastname: Hedjoudje
authors.forename: Charles C
authors.initials: CC
authors.lastname: Della Santina
mesh_terms: D004558:Electric Stimulation; D006801:Humans; D019736:Prostheses and Implants; D012027:Reflex, Vestibulo-Ocular / Q000502:physiology*; D014722:Vestibule, Labyrinth