title: One-year follow-up of patients with melamine-induced urolithiasis in Southwest China.
abstract: In 2008, more than 290,000 children suffered from urinary tract stones with a history of consuming melamine-contaminated powdered formula in China. Little was known about the long-term follow-up of outcomes of these patients in southwest China, so we conducted one-year follow-up investigation for further study. Thirty-six of 51 inpatients with melamine-induced urolithiasis were enrolled in this study. After 12 months follow-up, none of the children had vomiting, oliguria, gross hematuria, or fever. Twenty-seven patients were stone free, stones decreased in size in six patients and increased in three. Serum total protein, albumin, and pre-albumin increased significantly from baseline to 12 months, and renal function remained normal. Melamine-induced urolithiasis could not lead renal dysfunction at 12 months follow-up. The results of our study indicated that more attention should be paid to the prevention of protein malnutrition in children with a history of consuming melamine-contaminated food products.
authors.affiliation: Department of Laboratory Medicine, West China Second University Hospital, Sichuan University, Chengdu, China.
authors.forename: Qingkai
authors.initials: Q
authors.lastname: Dai
authors.forename: Yongmei
authors.initials: Y
authors.lastname: Jiang
authors.forename: Wenwei
authors.initials: W
authors.lastname: Tu
authors.forename: Hong
authors.initials: H
authors.lastname: Luo
authors.forename: Zheng
authors.initials: Z
authors.lastname: Wang
authors.forename: Yu-Lung
authors.initials: YL
authors.lastname: Lau
authors.forename: Hua
authors.initials: H
authors.lastname: Shi
authors.forename: Hui
authors.initials: H
authors.lastname: Yang
mesh_terms: D001774:Blood Chemical Analysis; D002648:Child; D002675:Child, Preschool; D002681:China; D005260:Female; D005500:Follow-Up Studies; D005506:Food Contamination; D006801:Humans; D007223:Infant; D041943:Infant Formula / Q000737:chemistry*; D007668:Kidney / Q000000981:diagnostic imaging / Q000473:pathology; D008297:Male; D014227:Triazines / Q000633:toxicity*; D014463:Ultrasonography; D016482:Urinalysis; D052878:Urolithiasis / Q000139:chemically induced* / Q000000981:diagnostic imaging* / Q000473:pathology / Q000628:therapy
chemical_list: D014227:Triazines; C011907:melamine