title: Novel capsular aggregates from flexible tripodal triureas with C(s) symmetry.
abstract: Tris(2- and 3-ureidobenzyl)amines with C(s)  symmetry self-assemble in solution forming mixtures of regioisomeric capsular aggregates, one of which is chiral and the other centrosymmetric. Under certain conditions, a predominance of the centrosymmetric regioisomer is found before equilibrium, that is, a mixture close to the statistical ratio of the two species is reached. In the solid state, there is a preference for the centrosymmetric capsules. Molecular models of both regioisomeric aggregates have been built and analyzed for comparison. Guests inside capsules formed by self-assembly of desymmetrized tris(3-ureidobenzyl)amines feel different magnetic environments, depending on whether they are inside a chiral or an achiral regioisomeric container. Of special significance are the experiments with a more flexible triurea endowed with an ureidopropylic arm, which self-assembles with the same efficiency as the more rigid tris(ureidobenzyl)amines.
authors.affiliation: Departamento de Quimica Organica, Facultad de Quimica, Universidad de Murcia, Campus de Espinardo, Murcia-30.100, Spain. alajarin@um.es
authors.forename: Mateo
authors.initials: M
authors.lastname: Alajarin
authors.forename: Raul-Angel
authors.initials: RA
authors.lastname: Orenes
authors.forename: Judith A K
authors.initials: JA
authors.lastname: Howard
authors.forename: Elinor C
authors.initials: EC
authors.lastname: Spencer
authors.forename: Jonathan W
authors.initials: JW
authors.lastname: Steed
authors.forename: Aurelia
authors.initials: A
authors.lastname: Pastor