title: [Enhanced serum DNAase activity in hypersensitization to pollen allergens].
abstract: Factor analysis of cross-sensitization to 24 common allergens and correlation analysis of the relationship between the hypersensitivity to the allergens and some biochemical markers (the intensity of serum chemiluminescence, the content of SH-groups, and the activity of lysosomal enzymes) of the health status were carried out in a sample of Moscow residents with allergic diseases. A significant correlation was found between the serum levels of specific IgE antibodies to pollen allergens and the activity of serum acid DNAase (R = 0.498; p = 0.009; N = 67). The revealed regularity may be used to devise a test for the differential diagnosis of pollenoses and suggests that there are possible differences in the levels of apoptosis and cytogenetic damages between patients with pollenoses and those with other allergic diseases.
authors.forename: L V
authors.initials: LV
authors.lastname: Khripach
authors.forename: A K
authors.initials: AK
authors.lastname: Makovetskaia
authors.forename: V N
authors.initials: VN
authors.lastname: Fedoseeva
authors.forename: Z I
authors.initials: ZI
authors.lastname: Koganova
authors.forename: E V
authors.initials: EV
authors.lastname: Zhelezniak
authors.forename: T D
authors.initials: TD
authors.lastname: Kniazeva
authors.forename: O V
authors.initials: OV
authors.lastname: Mislavskiĭ
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000485:Allergens / Q000276:immunology*; D003851:Deoxyribonucleases / Q000097:blood*; D005260:Female; D006801:Humans; D006967:Hypersensitivity / Q000097:blood / Q000201:enzymology*; D007073:Immunoglobulin E / Q000097:blood*; D008297:Male; D008875:Middle Aged; D009031:Moscow; D011058:Pollen / Q000276:immunology*; D012044:Regression Analysis; D055815:Young Adult
chemical_list: D000485:Allergens; D007073:Immunoglobulin E; D003851:Deoxyribonucleases