title: Total antioxidant capacity and total oxidant status of synovial fluids in patients with temporomandibular joint pain and dysfunction.
abstract: OBJECTIVE
  The objective of this study was to investigate whether a relationship exists between total antioxidant capacity (TAC) and total oxidant status (TOS) of synovial fluids (SFs) of temporomandibular joint (TMJ) pain patients with pain and dysfunction.
  
  
  METHODS
  Forty-two patients with TMJ pain were included in this study. TAC and TOS values of SFs were measured with a novel colorimetric method. Independent t test and correlations were used to analyze the data.
  
  
  RESULTS
  TAC of SFs in patients with TMJ pain and limited mouth opening (LMO; n = 21) were significantly lower (P = 0.03) than patients without LMO (n = 21). TOS of SF was negatively correlated with duration of the disease. There was no correlation between TAC, TOS, and VAS scores of the patients as well as age and maximum mouth opening values.
  
  
  CONCLUSIONS
  Antioxidant response to oxidative changes (TAC and TOS) in SF decreased as the stage of dysfunction increased.
  
  
  CONCLUSIONS
  Local administration of antioxidant agents might be considered in management of TMJ pain and dysfunction to prevent possible increased oxidative stress.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Erciyes University, 38039 Kayseri, Turkey.
authors.forename: Osman A
authors.initials: OA
authors.lastname: Etöz
authors.forename: Hüseyin
authors.initials: H
authors.lastname: Akçay
authors.forename: Salim
authors.initials: S
authors.lastname: Neşelioğlu
authors.forename: Özcan
authors.initials: Ö
authors.lastname: Erel
authors.forename: Alper
authors.initials: A
authors.lastname: Alkan
mesh_terms: D000328:Adult; D000975:Antioxidants / Q000032:analysis*; D003124:Colorimetry / Q000379:methods; D005157:Facial Pain / Q000473:pathology / Q000503:physiopathology; D005260:Female; D006801:Humans; D008297:Male; D016877:Oxidants / Q000737:chemistry*; D018384:Oxidative Stress / Q000502:physiology; D010147:Pain Measurement; D019152:Paracentesis / Q000379:methods; D016059:Range of Motion, Articular / Q000502:physiology; D013053:Spectrophotometry / Q000379:methods; D013582:Synovial Fluid / Q000737:chemistry*; D013706:Temporomandibular Joint Dysfunction Syndrome / Q000473:pathology* / Q000503:physiopathology; D013997:Time Factors
chemical_list: D000975:Antioxidants; D016877:Oxidants