title: Nicolau syndrome following intramuscular penicillin injection.
abstract: Nicolau Syndrome (NS) is a rare but severe localized adverse reaction at the site of intramuscular drug injection. The typical presentation is intense pain around the injection site soon after injection, followed by erythema, purplish network discolouration of the skin, haemorrhagic patch, and finally tissue necrosis. Here in, we report a 9 years old boy, the third Nicolau Syndrome (NS) reported from Iran after a single intramuscular injection of penicillin.
authors.affiliation: Department of Paediatrics, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
authors.forename: Mehran
authors.initials: M
authors.lastname: Karimi
authors.forename: Mohammad Bagher
authors.initials: MB
authors.lastname: Owlia
mesh_terms: D002648:Child; D003937:Diagnosis, Differential; D003875:Drug Eruptions / Q000175:diagnosis / Q000209:etiology*; D005218:Fat Necrosis / Q000139:chemically induced* / Q000473:pathology; D006801:Humans; D007273:Injections, Intramuscular / Q000009:adverse effects; D008279:Magnetic Resonance Imaging; D008297:Male; D018482:Muscle, Skeletal / Q000473:pathology*; D010406:Penicillins / Q000008:administration & dosage / Q000009:adverse effects*; D012867:Skin / Q000473:pathology*; D013577:Syndrome
chemical_list: D010406:Penicillins