title: [Ketamine-induced vesicopathy].
abstract: We report about a 25-year-old patient with transnasal ketamine abuse over years presenting with severe irritative urinary dysfunction (imperative urinary urgency, pollakisuria, dysuria) and severe alguria. Cystoscopia showed ketamine-induced vesicopathy with errosive cystitis; other etiologies could be excluded. Despite serious effort the patient was not motivated for abstinence from ketamine. After two ineffecient therapies with botulinum toxin A (200 and 400 I. E.) injected into the bladder, a prostate preserving cystectomia and ileum neobladder were mandatory.
authors.affiliation: Klinik und Poliklinik für Psychiatrie, Psychotherapie und Psychosomatik, Ludwig-Maximilians-Universität, München. martin.lieb@med.unimuenchen.de
authors.forename: Martin
authors.initials: M
authors.lastname: Lieb
authors.forename: Markus
authors.initials: M
authors.lastname: Bader
authors.forename: Ulrich
authors.initials: U
authors.lastname: Palm
authors.forename: Christian G
authors.initials: CG
authors.lastname: Stief
authors.forename: Thomas C
authors.initials: TC
authors.lastname: Baghai
mesh_terms: D000281:Administration, Intranasal; D000283:Administration, Intravesical; D000328:Adult; D000700:Analgesics / Q000008:administration & dosage / Q000009:adverse effects*; D019274:Botulinum Toxins, Type A / Q000008:administration & dosage; D015653:Cystectomy; D003556:Cystitis / Q000139:chemically induced / Q000175:diagnosis / Q000534:rehabilitation; D006679:HIV Seropositivity / Q000503:physiopathology / Q000523:psychology; D006801:Humans; D007649:Ketamine / Q000008:administration & dosage / Q000009:adverse effects*; D008297:Male; D010349:Patient Compliance / Q000523:psychology; D019966:Substance-Related Disorders / Q000150:complications* / Q000175:diagnosis* / Q000534:rehabilitation; D014547:Urinary Diversion; D014555:Urination Disorders / Q000139:chemically induced* / Q000175:diagnosis / Q000534:rehabilitation
chemical_list: D000700:Analgesics; D007649:Ketamine; D019274:Botulinum Toxins, Type A