title: [Expression of MEF2D on nasopharyngeal carcinoma tissues and its influence of prognostic].
abstract: OBJECTIVE
  To explore the expression of MEF2D in NPC tissues, study the relationship between the expression and prognostic.
  
  
  METHODS
  Specimens from 101 NPC patients who were follow-up visited 1 to 7 years were analyzed for MEF2D by using immunohistochemistry.
  
  
  RESULTS
  (1) The expression of MEF2D was higher in the higher clinical stage. (2) Density and Grey of MEF2D was negative correlated (|r| = 0.865, P < 0.01). (3) NPC patients' survival rate after therapies was 52.5%, the survival curve of 1th clinical stage was higher than 4th. (4) The survival curves of MEF2D stages were no statistical significance.
  
  
  CONCLUSIONS
  There's statistical significance of the MEF2D expression in clinical stages, but not in survival curve, which indicated that MEF2D concerned with invasion and metastatic of NPC.
authors.affiliation: Department of Otolaryngology, No. 303 Hospital of PLA, Nanning, China, 530021.
authors.forename: Yongling
authors.initials: Y
authors.lastname: Li
authors.forename: Longcheng
authors.initials: L
authors.lastname: Zhang
authors.forename: Jiang
authors.initials: J
authors.lastname: Nong
authors.forename: Shixia
authors.initials: S
authors.lastname: Bian
authors.forename: Zhen
authors.initials: Z
authors.lastname: Zhao
authors.forename: Yi
authors.initials: Y
authors.lastname: Ren
authors.forename: Xinran
authors.initials: X
authors.lastname: Lin
authors.forename: Xiuwu
authors.initials: X
authors.lastname: Bian
mesh_terms: D000328:Adult; D002277:Carcinoma; D002294:Carcinoma, Squamous Cell / Q000378:metabolism* / Q000473:pathology; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D026161:MADS Domain Proteins / Q000378:metabolism*; D064326:MEF2 Transcription Factors; D008297:Male; D008875:Middle Aged; D018006:Myogenic Regulatory Factors / Q000378:metabolism*; D000077274:Nasopharyngeal Carcinoma; D009303:Nasopharyngeal Neoplasms / Q000378:metabolism* / Q000473:pathology; D009367:Neoplasm Staging; D011379:Prognosis
chemical_list: D026161:MADS Domain Proteins; D064326:MEF2 Transcription Factors; C578043:MEF2D protein, human; D018006:Myogenic Regulatory Factors