title: γ knife radiosurgery of other brain metastases.
abstract: We evaluated the role of Gamma Knife stereotactic radiosurgery in the multidisciplinary management of brain metastases ovarian and endometrial, prostate, thyroid, sarcoma, or unknown primary cancers. From a series of over 3,000 patients who had Gamma Knife radiosurgery for brain metastases we reviewed indications and outcomes in patients with less common cancer types. All tumor types responded favorably to radiosurgery. Patients with male and female genitourinary primaries tended to develop brain metastases late in their course and did worse. Patients with thyroid metastases appear to live much longer with a more indolent course. Radiosurgery is an effective and safe minimally invasive option for patients with brain metastases from these less common primary origins.
authors.affiliation: Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA 15213, USA. kondds@upmc.edu
authors.forename: Douglas
authors.initials: D
authors.lastname: Kondziolka
authors.forename: Ajay
authors.initials: A
authors.lastname: Niranjan
authors.forename: Hideyuki
authors.initials: H
authors.lastname: Kano
authors.forename: John C
authors.initials: JC
authors.lastname: Flickinger
authors.forename: L Dade
authors.initials: LD
authors.lastname: Lunsford
mesh_terms: D001932:Brain Neoplasms / Q000556:secondary* / Q000601:surgery*; D004701:Endocrine Gland Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D009362:Neoplasm Metastasis; D009382:Neoplasms, Unknown Primary / Q000473:pathology*; D016634:Radiosurgery / Q000379:methods*; D012509:Sarcoma / Q000473:pathology*