title: Hashimoto encephalopathy causing drug-resistant status epilepticus treated with plasmapheresis.
abstract: Hashimoto encephalopathy is a rare, clinically heterogenous condition. Its treatment is based on corticosteroids. A previously normal 12-year-old boy was admitted to our pediatric emergency department with status epilepticus. He experienced a recurrence of status epilepticus after pentobarbital withdrawal, and required repeated resumptions of drug-induced coma. He manifested acute personality changes. His limbic encephalitis markers were normal, but his level of anti-thyroid peroxidase antibody was high. A diagnosis of Hashimoto encephalopathy was considered. Our patient responded to plasmapheresis instead of corticosteroid treatment. This case report is the first, to the best of our knowledge, of plasmapheresis because of Hashimoto encephalopathy in a child.
authors.affiliation: Department of Pediatric Neurology, Ankara University Medical School, Ankara, Turkey. bektasomer@gmail.com
authors.forename: Ömer
authors.initials: Ö
authors.lastname: Bektas
authors.forename: Arzu
authors.initials: A
authors.lastname: Yılmaz
authors.forename: Tanıl
authors.initials: T
authors.lastname: Kendirli
authors.forename: Zeynep
authors.initials: Z
authors.lastname: Sıklar
authors.forename: Gülhis
authors.initials: G
authors.lastname: Deda
mesh_terms: D001927:Brain Diseases / Q000150:complications*; D002648:Child; D004660:Encephalitis; D050031:Hashimoto Disease / Q000150:complications*; D006801:Humans; D008297:Male; D010956:Plasmapheresis; D013226:Status Epilepticus / Q000209:etiology / Q000628:therapy*; D016896:Treatment Outcome