title: [Kidney allograft: a target for systemic disease].
abstract: Recurrence of disease after transplantation is frequent and represents the third cause of allograft loss. Recurrence of lupus nephritis after transplantation is rare. Kidney transplantation in patients with antiphospholipid syndrome or lupus anticoagulant is challenging due to the high risk of immediate post-transplant thrombosis and bleeding risk associated to the subsequent anticoagulation. Moreover, vascular changes associated to the presence of antiphospholipid antibodies negatively impact allograft rate survival. Recurrence of pauci immune glomerulonephritis or Goodpasture syndrome is exceptional.
authors.affiliation: Université Paris-Descartes, hôpital Necker, service de transplantation et unité de soins intensifs, 75743 Paris cedex 15, France.
authors.forename: Guillaume
authors.initials: G
authors.lastname: Canaud
authors.forename: Christophe
authors.initials: C
authors.lastname: Legendre
mesh_terms: D019867:Anti-Glomerular Basement Membrane Disease / Q000175:diagnosis / Q000601:surgery; D056648:Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis / Q000175:diagnosis / Q000601:surgery; D016736:Antiphospholipid Syndrome / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D006084:Graft Rejection / Q000209:etiology; D006085:Graft Survival; D006801:Humans; D007674:Kidney Diseases / Q000209:etiology / Q000473:pathology / Q000601:surgery*; D016030:Kidney Transplantation; D016682:Lupus Coagulation Inhibitor; D008180:Lupus Erythematosus, Systemic / Q000175:diagnosis / Q000601:surgery; D008181:Lupus Nephritis / Q000601:surgery; D012008:Recurrence; D012189:Retrospective Studies; D013923:Thromboembolism / Q000209:etiology
chemical_list: D016682:Lupus Coagulation Inhibitor