title: N-heterocyclic carbene catalyzed reactions of α-bromo-α,β-unsaturated aldehydes/α,β-dibromoaldehydes with 1,3-dinucleophilic reagents.
abstract: Carbenes ring true: N-Heterocyclic carbene (NHC) catalyzed reactions of α-bromo-α,β-unsaturated aldehydes/α,β-dibromoaldehydes with 1,3-dinucleophilic reagents, such as 1,3-dicarbonyl compounds, β-enamino ketones, and β-enamino esters through umpolung processes gave functionalized 3,4-dihydropyranones and 3,4-dihydropyridinones. The availability of the starting materials, lack of external oxidant, and usefulness of the products make this strategy attractive.
authors.affiliation: School of Chemistry and Engineering, Key Laboratory of Biotechnology for Medicinal Plants, Xuzhou Normal University, Xuzhou, Jiangsu 221116, PR China. csyao@xznu.edu.cn
authors.forename: Changsheng
authors.initials: C
authors.lastname: Yao
authors.forename: Donglin
authors.initials: D
authors.lastname: Wang
authors.forename: Jun
authors.initials: J
authors.lastname: Lu
authors.forename: Tuanjie
authors.initials: T
authors.lastname: Li
authors.forename: Weihui
authors.initials: W
authors.lastname: Jiao
authors.forename: Chenxia
authors.initials: C
authors.lastname: Yu
mesh_terms: D000447:Aldehydes / Q000737:chemistry*; D002384:Catalysis; D004952:Esters; D006842:Hydrocarbons, Brominated / Q000737:chemistry*; D007202:Indicators and Reagents; D007659:Ketones / Q000138:chemical synthesis / Q000737:chemistry; D008697:Methane / Q000031:analogs & derivatives* / Q000737:chemistry; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D000447:Aldehydes; D004952:Esters; D006842:Hydrocarbons, Brominated; D007202:Indicators and Reagents; D007659:Ketones; C030011:carbene; D008697:Methane