title: Serotonin syndrome associated with MDPV use: a case report.
abstract: Serotonin syndrome is associated with use of certain street drugs, including methamphetamine, cocaine, and ecstasy. We describe a case of a woman who developed clinical findings consistent with serotonin syndrome after insufflation of 3,4-methylenedioxypyrovalerone (MDPV), a synthetic amphetamine. MDPV belongs to a group of substances called phenylethylamines, which are β-ketone analogs of other drugs of abuse, such as amphetamines and 3,4-methylenedioxymethamphetamine. She also received fentanyl initially during her hospitalization, which has also been associated with serotonin syndrome. In addition to benzodiazepines and supportive care, she was treated with cyproheptadine for 8 days, with slow resolution of her symptoms.
authors.affiliation: Indiana University School of Medicine, Indianapolis, IN, USA. jmugele@iupui.edu
authors.forename: Josh
authors.initials: J
authors.lastname: Mugele
authors.forename: Kristine A
authors.initials: KA
authors.lastname: Nañagas
authors.forename: Laura M
authors.initials: LM
authors.lastname: Tormoehlen
mesh_terms: D000328:Adult; D052117:Benzodioxoles / Q000506:poisoning*; D015198:Designer Drugs / Q000506:poisoning*; D005260:Female; D006801:Humans; D011759:Pyrrolidines / Q000506:poisoning*; D020230:Serotonin Syndrome / Q000139:chemically induced / Q000175:diagnosis*; D000094982:Synthetic Cathinone
chemical_list: D052117:Benzodioxoles; D015198:Designer Drugs; D011759:Pyrrolidines; D000094982:Synthetic Cathinone