title: [Studies on metabolites from marine microorganism Aspergillus terreus collected from nature reserve region of mangrove].
abstract: OBJECTIVE
  To search for new antitumor active lead compounds from marine microorganism.
  
  
  METHODS
  A marine strain, Aspergillus terreus, was cultured and up-scaled in artificial seawater media, from which the metabolites were isolated and elucidated by using modern spectroscopy techniques.
  
  
  RESULTS
  Twelve compounds were isolated from mycelia and fermentation broth of A. terreus.
  
  
  CONCLUSIONS
  Compounds 1-4 were steroids, compounds 5-8 were organic acids and esters, compound 9 was an alkaloid, compound 10 was an isocoumarin, compound 11 was ceramide, compound 12 was propenyl cyclic pentanediol.
authors.affiliation: Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Key laboratory of Biosynthesis of Natural Products, Ministry of Public Health, Key laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Beijing 100050, China.
authors.forename: Yi
authors.initials: Y
authors.lastname: Shen
authors.forename: Jianhua
authors.initials: J
authors.lastname: Zou
authors.forename: Jungui
authors.initials: J
authors.lastname: Dai
mesh_terms: D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification / Q000378:metabolism; D001230:Aspergillus / Q000737:chemistry* / Q000378:metabolism*; D002518:Ceramides / Q000737:chemistry / Q000302:isolation & purification / Q000378:metabolism; D003470:Culture Media / Q000737:chemistry / Q000378:metabolism; D004952:Esters / Q000737:chemistry / Q000302:isolation & purification / Q000378:metabolism; D049934:Isocoumarins / Q000737:chemistry / Q000302:isolation & purification / Q000378:metabolism; D025282:Mycelium / Q000737:chemistry* / Q000378:metabolism*; D011409:Propylene Glycols / Q000737:chemistry / Q000302:isolation & purification / Q000378:metabolism; D043982:Rhizophoraceae / Q000382:microbiology*; D013256:Steroids / Q000737:chemistry / Q000302:isolation & purification / Q000378:metabolism
chemical_list: D000470:Alkaloids; D002518:Ceramides; D003470:Culture Media; D004952:Esters; D049934:Isocoumarins; D011409:Propylene Glycols; D013256:Steroids