title: Distant plant homologues: don't throw out the baby.
abstract: Plants and metazoans share many similarities in terms of conserved proteins. Antibodies have been used extensively to detect remote homologues, many of which are yet to be identified conclusively. Genome sequencing and the creation of novel sequence or structure comparison programs have assisted greatly in the identification of distant protein homologues. The continuing development of new software algorithms and the combining of bioinformatics with proteomics offer hope that remaining homologues will be soon identified.
authors.affiliation: The School of Biological Sciences, The University of Sydney, Sydney, NSW 2006, Australia. jgardiner@mail.usyd.edu.au
authors.forename: John
authors.initials: J
authors.lastname: Gardiner
authors.forename: Robyn
authors.initials: R
authors.lastname: Overall
authors.forename: Jan
authors.initials: J
authors.lastname: Marc
mesh_terms: D000818:Animals; D019295:Computational Biology; D016208:Databases, Factual; D006801:Humans; D010944:Plants / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D040901:Proteomics; D017421:Sequence Analysis