title: Idiopathic granulomatous lobular mastitis.
abstract: Idiopathic granulomatous lobular mastitis (IGLM) is a rare breast condition with prominent skin findings. It is typically seen in young parous women. Painful breast masses, draining sinuses, scarring, and breast atrophy are the main clinical manifestations. IGLM can resemble a variety of other inflammatory and neoplastic processes of the breast. It is thought to result from obstruction and rupture of breast lobules. Extravasated breast secretions then induce an inflammatory reaction. Corynebacteria have also been implicated in the pathogenesis. Treatment is surgical, but systemic corticosteroids, methotrexate, and antibiotics also play a role.
authors.affiliation: Mount Sinai School of Medicine, New York, NY, USA.
authors.forename: Frederick A
authors.initials: FA
authors.lastname: Pereira
authors.forename: Adarsh V
authors.initials: AV
authors.lastname: Mudgil
authors.forename: Edgar S
authors.initials: ES
authors.lastname: Macias
authors.forename: Karen
authors.initials: K
authors.lastname: Karsif
mesh_terms: D003937:Diagnosis, Differential; D058890:Granulomatous Mastitis / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D006801:Humans; D011379:Prognosis