title: Mathematical, numerical and experimental study in the human aorta with coexisting models of bicuspid aortic stenosis and coarctation of the aorta.
abstract: Coarctation of the aorta is an obstruction of the aorta and is usually associated with other concomitant cardiovascular abnormalities especially with bicuspid aortic valve stenosis. The objectives of this study are, (1) to investigate the effects of coarctation on the hemodynamics in the aorta to gain a better understanding of the cause of certain post-surgical coarctation problems, (2) to develop and introduce a new lumped parameter model, mainly based on non-invasive data, allowing the description of the interaction between left ventricle, coarctation of the aorta, aortic valve stenosis, and the arterial system.
authors.affiliation: Mechanical and Industrial Engineering, Concordia University, Montréal, Canada. z_kesha@encs.concordia.ca
authors.forename: Z
authors.initials: Z
authors.lastname: Keshavarz-Motamed
authors.forename: J
authors.initials: J
authors.lastname: Garcia
authors.forename: L
authors.initials: L
authors.lastname: Kadem
mesh_terms: D001011:Aorta / Q000503:physiopathology*; D001017:Aortic Coarctation / Q000503:physiopathology*; D001024:Aortic Valve Stenosis / Q000503:physiopathology*; D001783:Blood Flow Velocity; D001794:Blood Pressure; D003198:Computer Simulation; D006801:Humans; D008943:Mitral Valve / Q000503:physiopathology*; D008955:Models, Cardiovascular