title: Comparison of the effect of various irrigants on apically extruded debris after root canal preparation.
abstract: BACKGROUND
  Several factors can influence the amount of apically extruded debris. The aim was to quantitatively compare the amount of debris extruded apically from root canals when 3 different irrigants were used during canal preparation with rotary instruments.
  
  
  METHODS
  Ninety-one extracted single-rooted human mandibular premolar teeth with straight root canals were used. The teeth were randomly divided into 1 control group (group 1, n = 4) and 3 experimental groups of 29 teeth each. Hero 642 instruments were used for root canal preparation in all teeth, and 3 different irrigants were used (group 2, 2% chlorhexidine; group 3, 5.25% sodium hypochlorite; group 4, 2.5% sodium hypochlorite). Seven Eppendorf tubes served as a second control group. Debris extruded from the apical foramen during root canal preparation was collected into preweighed Eppendorf tubes. The weight of the dry extruded debris was established by subtracting the preinstrumentation and postinstrumentation weight of the Eppendorf tubes for each group. The data obtained were analyzed by using one-way analysis of variance and Tukey honestly significant difference.
  
  
  RESULTS
  Group 3 (sodium hypochlorite 5.25%) had the highest amount of extruded debris, which was significantly different from the other groups (P < .05).
  
  
  CONCLUSIONS
  The type of irrigant used can affect the amount of apically extruded debris. The 5.25% solution of sodium hypochlorite had the greatest amount of debris.
authors.affiliation: Oral and Dental Diseases Research Center, Kerman, Iran. masoudparirokh@yahoo.com
authors.forename: Masoud
authors.initials: M
authors.lastname: Parirokh
authors.forename: Shahrzad
authors.initials: S
authors.lastname: Jalali
authors.forename: Ali Akbar
authors.initials: AA
authors.lastname: Haghdoost
authors.forename: Paul Vincent
authors.initials: PV
authors.lastname: Abbott
mesh_terms: D001641:Bicuspid / Q000187:drug effects; D002710:Chlorhexidine / Q000008:administration & dosage; D003786:Dental Pulp Cavity / Q000473:pathology*; D005119:Extravasation of Diagnostic and Therapeutic Materials / Q000209:etiology*; D006801:Humans; D012388:Root Canal Irrigants / Q000008:administration & dosage*; D018915:Root Canal Preparation / Q000295:instrumentation / Q000379:methods*; D012973:Sodium Hypochlorite / Q000008:administration & dosage; D007507:Therapeutic Irrigation / Q000009:adverse effects; D019227:Tooth Apex / Q000473:pathology*
chemical_list: D012388:Root Canal Irrigants; D012973:Sodium Hypochlorite; D002710:Chlorhexidine