title: The first neural probe integrated with light source (blue laser diode) for optical stimulation and electrical recording.
abstract: In this paper, we report a neural probe which can selectively stimulate target neurons optically through Si wet etched mirror surface and record extracellular neural signals in iridium oxide tetrodes. Consequently, the proposed approach provides to improve directional problem and achieve at least 150/m gap distance between stimulation and recording sites by wet etched mirror surface in V-groove. Also, we developed light source, blue laser diode (OSRAM Blue Laser Diode_PL 450), integration through simple jig for one-touch butt-coupling. Furthermore, optical power and impedance of iridium oxide tetrodes were measured as 200 μW on 5 mW from LD and 206.5 k Ω at 1 kHz and we demonstrated insertion test of probe in 0.5% agarose-gel successfully. We have successfully transmitted a light of 450 nm to optical fiber through the integrated LD using by butt-coupling method.
authors.affiliation: Center for Bionics of Korea Institute of Scienceand Technology, Seoul 136-791, South Korea. phdpower@kist.re.kr
authors.forename: HyungDal
authors.initials: H
authors.lastname: Park
authors.forename: Hyun-Joon
authors.initials: HJ
authors.lastname: Shin
authors.forename: Il-Joo
authors.initials: IJ
authors.lastname: Cho
authors.forename: Eui-sung
authors.initials: ES
authors.lastname: Yoon
authors.forename: Jun-Kyo Francis
authors.initials: JK
authors.lastname: Suh
authors.forename: Maesoon
authors.initials: M
authors.lastname: Im
authors.forename: Euisik
authors.initials: E
authors.lastname: Yoon
authors.forename: Yong-Jun
authors.initials: YJ
authors.lastname: Kim
authors.forename: Jinseok
authors.initials: J
authors.lastname: Kim
mesh_terms: D006801:Humans; D008027:Light; D009474:Neurons / Q000502:physiology*