title: H1N1 infection in children with hematological malignancies.
abstract: In the recent pandemic of H1N1 infection, pediatric patients with haematological malignancies were considered high risk for severe illness. There is paucity of data regarding course of H1N1 infection in this subgroup. We describe H1N1 infection in 3 children with acute leukemia. All three patients presented with neutropenic fever; 2 had probable fungal pneumonia based on chest imaging and galactomanan estimation. Diagnosis of H1N1 infection was delayed in all 3 patients as it was not suspected initially. One patient died despite treatment. H1NI infection may coexist with other infections in febrile neutropenia.
authors.affiliation: Department of Medical Oncology, Dr BRA Institute Rotary Cancer Hospital, and All India Institute of Medical Sciences, New Delhi 110 029, India.
authors.forename: Prabhat S
authors.initials: PS
authors.lastname: Malik
authors.forename: Shobha
authors.initials: S
authors.lastname: Broor
authors.forename: Sameer
authors.initials: S
authors.lastname: Bakhshi
mesh_terms: D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000998:Antiviral Agents / Q000627:therapeutic use; D002648:Child; D017809:Fatal Outcome; D005260:Female; D019337:Hematologic Neoplasms / Q000821:virology*; D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype; D007251:Influenza, Human / Q000150:complications* / Q000188:drug therapy; D008297:Male
chemical_list: D000900:Anti-Bacterial Agents; D000998:Antiviral Agents