title: Mechanisms and consequences of the loss of PHLPP1 phosphatase in chronic lymphocytic leukemia (CLL).
authors.forename: M
authors.initials: M
authors.lastname: O'Hayre
authors.forename: M
authors.initials: M
authors.lastname: Niederst
authors.forename: J F
authors.initials: JF
authors.lastname: Fecteau
authors.forename: V M
authors.initials: VM
authors.lastname: Nguyen
authors.forename: T J
authors.initials: TJ
authors.lastname: Kipps
authors.forename: D
authors.initials: D
authors.lastname: Messmer
authors.forename: A C
authors.initials: AC
authors.lastname: Newton
authors.forename: T M
authors.initials: TM
authors.lastname: Handel
mesh_terms: D001402:B-Lymphocytes / Q000166:cytology / Q000378:metabolism*; D015153:Blotting, Western; D016022:Case-Control Studies; D019175:DNA Methylation; D006801:Humans; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000201:enzymology* / Q000235:genetics / Q000473:pathology; D019950:Mitogen-Activated Protein Kinase 1 / Q000235:genetics / Q000378:metabolism; D048052:Mitogen-Activated Protein Kinase 3 / Q000235:genetics / Q000378:metabolism; D009687:Nuclear Proteins / Q000235:genetics* / Q000378:metabolism*; D010749:Phosphoprotein Phosphatases / Q000235:genetics* / Q000378:metabolism*; D010766:Phosphorylation; D011401:Promoter Regions, Genetic / Q000235:genetics; D011493:Protein Kinase C / Q000235:genetics / Q000378:metabolism; D064546:Protein Kinase C beta; D051057:Proto-Oncogene Proteins c-akt / Q000235:genetics / Q000378:metabolism; D020871:RNA Stability; D012333:RNA, Messenger / Q000235:genetics; D060888:Real-Time Polymerase Chain Reaction; D019718:Receptors, CXCR4 / Q000235:genetics / Q000378:metabolism; D020133:Reverse Transcriptase Polymerase Chain Reaction; D014407:Tumor Cells, Cultured
chemical_list: C527276:CXCR4 protein, human; D009687:Nuclear Proteins; D012333:RNA, Messenger; D019718:Receptors, CXCR4; D051057:Proto-Oncogene Proteins c-akt; D011493:Protein Kinase C; D064546:Protein Kinase C beta; C535150:MAPK1 protein, human; D019950:Mitogen-Activated Protein Kinase 1; D048052:Mitogen-Activated Protein Kinase 3; C400601:PHLPP1 protein, human; D010749:Phosphoprotein Phosphatases