title: Development and clinical application of a length-adjustable water phantom for total body irradiation.
abstract: A new type of water phantom which would be specialised for the absorbed dose measurement in total body irradiation (TBI) treatment is developed. Ten millimetres of thick Plexiglas plates were arranged to form a square cube with 300 mm of edge length. An appropriate sleeve-type piston was installed on the side wall, and a tabular Plexiglas piston was positioned inside the sleeve. By pushing and pulling the piston, the length of the self-made water phantom could be varied to meet the required patients' physical sizes. To compare the international standard water phantom with the length-adjustable and the Plexiglas phantoms, absorbed dose for 6-MV X ray was measured by an ionisation chamber at different depths in three kinds of phantoms. In 70 cases with TBI, midplane doses were metered using the length-adjustable and the Plexiglas phantoms for simulating human dimensions, and dose validation was synchronously carried out. There were no significant statistical differences, p > 0.05, through statistical processing of data from the international standard water phantom and the self-designed one. There were significant statistical differences, p < 0.05, between the two sets of data from the standard and the Plexiglas one. In addition, the absolute difference had a positive correlation with the varied depth of the detector in the Plexiglas phantom. Comparing the data of clinical treatment, the differences were all <1 % among the prescription doses and the validation data collected from the self-design water phantom. However, the differences collected from the Plexiglas phantom were increasing gradually from +0.77 to +2.30 % along with increasing body width. Obviously, the difference had a positive correlation with the body width. The results proved that the new length-adjustable water phantom is more accurate for simulating human dimensions than Plexiglas phantom.
authors.affiliation: Department of Oncology, Shanghai Jiaotong University, Shanghai, China. czw0123456789@163.com
authors.forename: Zhi-Wei
authors.initials: ZW
authors.lastname: Chen
authors.forename: Sheng-Yu
authors.initials: SY
authors.lastname: Yao
authors.forename: Tie-Ning
authors.initials: TN
authors.lastname: Zhang
authors.forename: Zhen-Hua
authors.initials: ZH
authors.lastname: Zhu
authors.forename: Zhe-Kai
authors.initials: ZK
authors.lastname: Hu
authors.forename: Xun
authors.initials: X
authors.lastname: Lu
mesh_terms: D006801:Humans; D009010:Monte Carlo Method; D019047:Phantoms, Imaging; D019904:Polymethyl Methacrylate / Q000737:chemistry; D011879:Radiotherapy Dosage; D014867:Water / Q000737:chemistry*; D014916:Whole-Body Irradiation
chemical_list: D014867:Water; D019904:Polymethyl Methacrylate