title: Spontaneous neurotransmission: a SNARE for the rest.
abstract: In addition to activity-dependent neurotransmission, neurons can undergo spontaneous activity-independent neurotransmitter release with low probability. In this issue of Neuron, Ramirez et al. (2012) now identify the noncanonical endosomal SNARE Vps10p-tail-interactor1a (Vti1a) as a regulator of spontaneously fusing vesicles.
authors.affiliation: Freie Universität Berlin, NeuroCure Cluster of Excellence & Charité Berlin, 14195 Berlin, Germany.
authors.forename: Natalia L
authors.initials: NL
authors.lastname: Kononenko
authors.forename: Volker
authors.initials: V
authors.lastname: Haucke
mesh_terms: D000818:Animals; D009474:Neurons / Q000502:physiology*; D050766:Qb-SNARE Proteins / Q000378:metabolism*; D013569:Synapses / Q000378:metabolism*; D009435:Synaptic Transmission / Q000502:physiology*; D013572:Synaptic Vesicles / Q000378:metabolism*
chemical_list: D050766:Qb-SNARE Proteins; C491417:Vti1a protein, rat