title: External ecological niche for Candida albicans within reducing, oxygen-limited zones of wetlands.
abstract: Candida albicans within the human host is well studied; however, identifying environmental reservoirs of pathogens is epidemiologically valuable for disease management. Oxygen-limited, carbohydrate-rich zones of wetlands, to which sewage-borne C. albicans is often exposed, are characteristically similar to the gastrointestinal reservoir. Consequently, using quantitative real-time PCR (qRT-PCR) and gas chromatography-mass spectrometry (GC-MS), we demonstrated that oxygen-limited zones in polluted wetlands may act as potential reservoirs of C. albicans.
authors.affiliation: Department of Microbiology, Stellenbosch University, Stellenbosch, South Africa.
authors.forename: Wendy
authors.initials: W
authors.lastname: Stone
authors.forename: Barbara-Lee
authors.initials: BL
authors.lastname: Jones
authors.forename: Jac
authors.initials: J
authors.lastname: Wilsenach
authors.forename: Alfred
authors.initials: A
authors.lastname: Botha
mesh_terms: D000693:Anaerobiosis; D002176:Candida albicans / Q000254:growth & development* / Q000302:isolation & purification / Q000378:metabolism; D015169:Colony Count, Microbial; D003470:Culture Media; D004197:Disease Reservoirs; D017753:Ecosystem; D004755:Enterobacteriaceae / Q000302:isolation & purification; D008401:Gas Chromatography-Mass Spectrometry; D006801:Humans; D010100:Oxygen / Q000494:pharmacology; D060888:Real-Time Polymerase Chain Reaction; D012722:Sewage / Q000382:microbiology*; D014876:Water Pollution; D053833:Wetlands
chemical_list: D003470:Culture Media; D012722:Sewage; D010100:Oxygen