title: Natural history of stent edge dissection, tissue protrusion and incomplete stent apposition detectable only on optical coherence tomography after stent implantation – preliminary observation – .
abstract: BACKGROUND
  The clinical impact of stent edge dissection, tissue protrusion, and incomplete stent apposition (ISA) after stent implantation, detectable only on optical coherence tomography (OCT), is still unknown because the natural course has not been investigated.
  
  
  RESULTS
  All consecutive patients with angina pectoris in whom both intravascular ultrasound (IVUS) and OCT were performed immediately after stenting and at follow-up were included in the present study. The natural history of OCT-detected stent edge dissection, tissue protrusion, and ISA during follow-up was investigated. A total of 36 patients with 39 lesions was analyzed. At baseline, OCT showed 12 stent edge dissections, 25 tissue protrusions, and 8 ISAs, whereas IVUS demonstrated 6 stent edge dissections, 5 tissue protrusions, and 3 ISAs. All IVUS findings were clearly visualized on OCT. The maximum length of dissection flap and depth of ISA visualized on OCT were significantly shorter than those visualized on IVUS. Maximum length of tissue protrusion tended to be smaller on OCT than on IVUS. At follow-up (median 188 days), all findings noted on OCT were healed or resolved without any restenosis or thrombus formation.
  
  
  CONCLUSIONS
  Acute findings after stenting, such as edge dissection, tissue protrusion, and ISA, detectable only on OCT, tended to be smaller than those seen on both OCT and IVUS. The majority of OCT-detected acute findings resolved completely at follow-up.
authors.affiliation: Department of Cardiology, Kawasaki Medical School, Kurashiki, Japan. tteru@med.kawasaki-m.ac.jp
authors.forename: Teruyoshi
authors.initials: T
authors.lastname: Kume
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Okura
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Miyamoto
authors.forename: Ryotaro
authors.initials: R
authors.lastname: Yamada
authors.forename: Ken
authors.initials: K
authors.lastname: Saito
authors.forename: Tomoko
authors.initials: T
authors.lastname: Tamada
authors.forename: Terumasa
authors.initials: T
authors.lastname: Koyama
authors.forename: Yoji
authors.initials: Y
authors.lastname: Neishi
authors.forename: Akihiro
authors.initials: A
authors.lastname: Hayashida
authors.forename: Takahiro
authors.initials: T
authors.lastname: Kawamoto
authors.forename: Kiyoshi
authors.initials: K
authors.lastname: Yoshida
mesh_terms: D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D019370:Observation; D011391:Prolapse; D015607:Stents / Q000009:adverse effects*; D041623:Tomography, Optical Coherence; D018084:Ultrasonography, Interventional