title: Roux-en-Y choledochojejunostomy using novel magnetic compressive anastomats in canine model of obstructive jaundice.
abstract: BACKGROUND
  The traditional hand-sewn Roux-en-Y choledochojejunostomy is technically complicated, and the incidence of postoperative complications has remained high. A set of novel magnetic compressive anastomats was introduced to facilitate choledochojejunostomy and improve the prognosis of patients.
  
  
  METHODS
  After ligating the common bile duct for 7 days, 16 dogs were randomly divided into two groups (n=8 per group). Anastomats were used in the study group, and the traditional hand-sewn method was used in the control group for standard Roux-en-Y choledochojejunostomy. We compared the operation time, incidence of complications, gross appearance, and pathological disparity in stoma between the two groups in 1-month and 3-month follow-up examinations.
  
  
  RESULTS
  The time spent on constructing the anastomosis for the study group was significantly shortened. Although no anastomotic stenosis occurred in the two groups, the narrowing rate of biliary-enteric anastomosis was much higher in the control group. There was one case of bile leakage in the control group, whereas no bile leakage occurred in the study group. A smoother surface, an improved layer apposition, and a lower local inflammatory response were identified in the anastomosis of the study group.
  
  
  CONCLUSIONS
  The structures of the novel magnetic compressive anastomats are simple, and they are time-saving, safe and efficient for performing Roux-en-Y choledochojejunostomy procedures in a canine model of obstructive jaundice.
authors.affiliation: Department of Hepatobiliary Surgery, First Affiliated Hospital, School of Medicine, Xi'an Jiaotong University, Xi'an, China.
authors.forename: Chao
authors.initials: C
authors.lastname: Fan
authors.forename: Xiao-Peng
authors.initials: XP
authors.lastname: Yan
authors.forename: Shi-Qi
authors.initials: SQ
authors.lastname: Liu
authors.forename: Chun-Bao
authors.initials: CB
authors.lastname: Wang
authors.forename: Jian-Hui
authors.initials: JH
authors.lastname: Li
authors.forename: Liang
authors.initials: L
authors.lastname: Yu
authors.forename: Zheng
authors.initials: Z
authors.lastname: Wu
authors.forename: Yi
authors.initials: Y
authors.lastname: Lv
mesh_terms: D000713:Anastomosis, Roux-en-Y / Q000009:adverse effects / Q000295:instrumentation*; D000818:Animals; D001663:Bilirubin / Q000097:blood; D015415:Biomarkers / Q000097:blood; D002768:Choledochostomy / Q000009:adverse effects / Q000295:instrumentation*; D004195:Disease Models, Animal; D004285:Dogs; D004867:Equipment Design; D041781:Jaundice, Obstructive / Q000097:blood / Q000601:surgery*; D008280:Magnetics / Q000295:instrumentation*; D008297:Male; D013523:Surgical Equipment; D013997:Time Factors
chemical_list: D015415:Biomarkers; D001663:Bilirubin