title: Morphology of endocrine organs in chronic endogenous intoxication.
abstract: Experimental study of the effects of endogenous toxic compounds on endocrine organs showed that the pathomorphological changes were caused by the cytopathic effects of endogenous toxic compounds involving the development of stereotypical reactions to injury. The severity of these reactions depended on the initial functional status of the gland and its involvement in systemic mechanisms of adaptation to the toxic process.
authors.affiliation: Volgograd State Medical University, Moscow, Russia. kalashnikova-sa@yandex.ru
authors.forename: S A
authors.initials: SA
authors.lastname: Kalashnikova
authors.forename: L V
authors.initials: LV
authors.lastname: Polyakova
authors.forename: A I
authors.initials: AI
authors.lastname: Shchyogolev
mesh_terms: D000311:Adrenal Glands / Q000276:immunology / Q000378:metabolism / Q000473:pathology; D000818:Animals; D053148:Caspase 3 / Q000378:metabolism; D002452:Cell Count; D004487:Edema / Q000276:immunology; D004703:Endocrine System / Q000276:immunology / Q000473:pathology; D042783:Endothelial Cells / Q000378:metabolism; D019446:Endotoxemia / Q000276:immunology / Q000473:pathology*; D005260:Female; D007249:Inflammation / Q000276:immunology; D007515:Islets of Langerhans / Q000276:immunology / Q000473:pathology; D008070:Lipopolysaccharides / Q000494:pharmacology; D008099:Liver / Q000276:immunology / Q000473:pathology; D008297:Male; D052250:Nitric Oxide Synthase Type III / Q000378:metabolism; D010286:Paraventricular Hypothalamic Nucleus / Q000276:immunology / Q000473:pathology; D010903:Pituitary Gland, Anterior / Q000276:immunology / Q000378:metabolism / Q000473:pathology; D051381:Rats; D053221:TNF-Related Apoptosis-Inducing Ligand / Q000378:metabolism; D013961:Thyroid Gland / Q000276:immunology / Q000473:pathology
chemical_list: D008070:Lipopolysaccharides; D053221:TNF-Related Apoptosis-Inducing Ligand; C505655:Tnfsf10 protein, rat; D052250:Nitric Oxide Synthase Type III; C496316:Nos3 protein, rat; C505410:Casp3 protein, rat; D053148:Caspase 3