title: CAP sleep in insomnia: new methodological aspects for sleep microstructure analysis.
abstract: This work aims to propose new methodologies for the quantitative characterization of insomnia. Sleep microstructure, as expressed by Cyclic Alternatic pattern (CAP) sleep, is studied and differences between normal sleepers and insomniacs are investigated. The dynamic in the structure of CAP activation events is studied by use of wavelet analysis and the content of events, i.e. EEG dynamics, is studied in terms of complexity analysis. Both in structure and content, features exhibiting statistically significant differences are proposed, opening new perspectives for the understanding and the quantitative characterization of sleep and its disorders.
authors.affiliation: Lab of Medical Informatics, Aristotle University of Thessaloniki, Greece. ioannach@auth.gr
authors.forename: I
authors.initials: I
authors.lastname: Chouvarda
authors.forename: M O
authors.initials: MO
authors.lastname: Mendez
authors.forename: V
authors.initials: V
authors.lastname: Rosso
authors.forename: A M
authors.initials: AM
authors.lastname: Bianchi
authors.forename: L
authors.initials: L
authors.lastname: Parrino
authors.forename: A
authors.initials: A
authors.lastname: Grassi
authors.forename: M
authors.initials: M
authors.lastname: Terzano
authors.forename: N
authors.initials: N
authors.lastname: Maglaveras
authors.forename: S
authors.initials: S
authors.lastname: Cerutti
mesh_terms: D000204:Activity Cycles; D000328:Adult; D000465:Algorithms; D003936:Diagnosis, Computer-Assisted / Q000379:methods*; D004569:Electroencephalography / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D007319:Sleep Initiation and Maintenance Disorders / Q000175:diagnosis* / Q000503:physiopathology*; D012894:Sleep Stages; D058067:Wavelet Analysis