title: Comparison of morbidity associated with laparoscopic myomectomy and hysterectomy for the treatment of uterine leiomyomas.
abstract: OBJECTIVE
  To compare short-term morbidity and quality of life after laparoscopic hysterectomy (LH) and laparoscopic myomectomy (LM) for the treatment of symptomatic uterine leiomyomas.
  
  
  METHODS
  We performed a prospective, observational study of women who were eligible for both surgical procedures. After informed consent was obtained, each participant was asked to complete the SF-12v2 Health Survey before surgery and to repeat it seven days and 28 days after surgery. Data on short-term morbidities, such as operative time, blood loss, length of hospital stay, and surgical complications, were collected by an obstetrician-gynaecologist. Women who underwent LH were compared by non-parametric statistical analyses with those who underwent LM.
  
  
  RESULTS
  Sixty-one women were recruited between January 1 and December 31, 2008, including 40 who underwent LM and 21 LH. Women who underwent LH were older, had higher parity, and were less likely to have infertility than those who chose LM. Median LH operative time of 223 minutes (IQR 214 to 241) was slightly longer than for LM (188 minutes, IQR 154 to 239; P = 0.02). However, we found no difference between the two groups in terms of SF-12v2 fluctuation, blood loss, hospital stay, and short-term complications.
  
  
  CONCLUSIONS
  Laparoscopic myomectomy is a viable alternative to laparoscopic hysterectomy for women with symptomatic leiomyomas who want conservative surgery. The procedures have similar morbidity and impact on quality of life.
authors.affiliation: Department of Obstetrics and Gynecology, Stanford University Medical Center, Palo Alto CA; Department of Obstetrics and Gynecology, Faculty of Medicine, Laval University, Quebec City QC.
authors.forename: Madeleine
authors.initials: M
authors.lastname: Lemyre
authors.affiliation: Department of Obstetrics and Gynecology, Faculty of Medicine, Laval University, Quebec City QC.
authors.forename: Emmanuel
authors.initials: E
authors.lastname: Bujold
authors.affiliation: Department of Obstetrics and Gynecology, Stanford University Medical Center, Palo Alto CA.
authors.forename: Ruth
authors.initials: R
authors.lastname: Lathi
authors.affiliation: Department of Obstetrics and Gynecology, Stanford University Medical Center, Palo Alto CA.
authors.forename: Lisa
authors.initials: L
authors.lastname: Bhagan
authors.affiliation: Department of Obstetrics and Gynecology, Stanford University Medical Center, Palo Alto CA.
authors.forename: Jian Qun
authors.initials: JQ
authors.lastname: Huang
authors.affiliation: Department of Obstetrics and Gynecology, Stanford University Medical Center, Palo Alto CA; Department of Surgery, Stanford University Medical Center, Palo Alto CA.
authors.forename: Camran
authors.initials: C
authors.lastname: Nezhat
mesh_terms: D000328:Adult; D016063:Blood Loss, Surgical; D005260:Female; D005500:Follow-Up Studies; D013509:Gynecologic Surgical Procedures / Q000379:methods*; D006306:Health Surveys; D006801:Humans; D007044:Hysterectomy / Q000379:methods*; D010535:Laparoscopy / Q000379:methods*; D007889:Leiomyoma / Q000473:pathology / Q000601:surgery*; D007902:Length of Stay; D008875:Middle Aged; D011183:Postoperative Complications; D011446:Prospective Studies; D016896:Treatment Outcome; D014594:Uterine Neoplasms / Q000473:pathology / Q000601:surgery*