title: The characterization of dynamic susceptibility effects.
abstract: Understanding and quantifying dynamic susceptibility contrast, which arises from compartmentalized magnetic field perturbers (e.g., deoxyhemoglobin, contrast agents) that affect the water around them, formed the basis of a significant part of the author's fMRI-related research in the early 90's. This short note describes how the scientific work used to help understand and quantify dynamic injections of contrast agents, primarily designed for clinical MRI, was adapted to help quantify and explain BOLD imaging.
authors.affiliation: robert.weisskoff@fmr.com
authors.forename: Robert M
authors.initials: RM
authors.lastname: Weisskoff
mesh_terms: D001921:Brain / Q000098:blood supply / Q000502:physiology; D001931:Brain Mapping / Q000266:history* / Q000379:methods; D003287:Contrast Media / Q000266:history* / Q000494:pharmacology; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000266:history* / Q000379:methods; D010100:Oxygen / Q000097:blood
chemical_list: D003287:Contrast Media; D010100:Oxygen