title: Achalasia and esophago-gastric junction outflow obstruction: focus on the subtypes.
abstract: BACKGROUND
  The choice between pneumatic dilation and surgical myotomy is mainly determined by the preference and expertise of the treating physician. Ideally, however, treatment should be personalized to provide the optimal clinical outcome. The introduction of high resolution manometry has not only improved the specificity to diagnose achalasia, but also identified three different manometric subclasses.
  
  
  OBJECTIVE
  To review, the data suggesting differences in clinical response to treatment depending on the manometric profile.
authors.affiliation: Department of Gastroenterology, Translational Research Centre for Gastrointestinal Disorders, University Hospital Leuven, Catholic University of Leuven, Leuven, Belgium. guy.boeckxstaens@med.kuleuven.be
authors.forename: G
authors.initials: G
authors.lastname: Boeckxstaens
authors.forename: G
authors.initials: G
authors.lastname: Zaninotto
mesh_terms: D004931:Esophageal Achalasia / Q000145:classification* / Q000175:diagnosis* / Q000628:therapy*; D006801:Humans; D008365:Manometry / Q000379:methods*