title: Synthetic approaches to the 2010 new drugs.
abstract: New drugs are introduced to the market every year and each represents a privileged structure for its biological target. These new chemical entities (NCEs) provide insights into molecular recognition and also serve as leads for designing future new drugs. This review covers the synthesis of 15 NCEs that were launched anywhere in the world in 2010.
authors.affiliation: Pfizer Inc., La Jolla, CA 92037, USA. Kevin.k.liu@pfizer.com
authors.forename: Kevin K-C
authors.initials: KK
authors.lastname: Liu
authors.forename: Subas M
authors.initials: SM
authors.lastname: Sakya
authors.forename: Christopher J
authors.initials: CJ
authors.lastname: O'Donnell
authors.forename: Andrew C
authors.initials: AC
authors.lastname: Flick
authors.forename: Hong X
authors.initials: HX
authors.lastname: Ding
mesh_terms: D060326:Chemistry Techniques, Synthetic / Q000379:methods*; D015195:Drug Design; D015394:Molecular Structure; D004364:Pharmaceutical Preparations / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D004364:Pharmaceutical Preparations