title: [Clinical observation of mucoregulatory agents' application after chronic rhinosinusitis surgery].
abstract: OBJECTIVE
  To explore the effect of mucoregulatory agents during endoscopic sinus surgery.
  
  
  METHODS
  Ninety-seven cases with chronic rhinosinusitis were randomly divided into three groups, with 31 cases in B group treated by ambroxol, 33 cases in C group treated by eucalyptol-limonene-pinene enteric soft capsule and 33 cases in control group (A group). The follow-up visit lasted for 6 months for three groups. Then, the therapeutic effects were evaluated and compared among these three groups.
  
  
  RESULTS
  By the end of 6 months after treatment,the effective rate was 90.3% and 97.0% for cases in the B and C groups respectively, and only 75.8% in A group. The difference between A and C was statistically significant (P < 0.05).
  
  
  CONCLUSIONS
  Eucalyptol-limonene-pinene enteric soft capsule,as a multicomponent mucoregulatory agent, can obviously improve the secretion of mucosa and epithelial recovery, thus accelerate healing of the disease. It can also improve the success rate of functional endoscope sinus surgery, and may play a promising role in clinical application.
authors.affiliation: Department of Center of Otorhinolaryngology of PLA, Navy General Hospital, Beijing, 100048, China.
authors.forename: Jianjun
authors.initials: J
authors.lastname: Sun
authors.forename: Jin
authors.initials: J
authors.lastname: Qian
authors.forename: Jing
authors.initials: J
authors.lastname: Zhao
authors.forename: Liang
authors.initials: L
authors.lastname: Liu
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000551:Ambroxol / Q000627:therapeutic use*; D002908:Chronic Disease; D003511:Cyclohexanols / Q000627:therapeutic use*; D053138:Cyclohexenes / Q000627:therapeutic use*; D000077591:Eucalyptol; D005100:Expectorants / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007432:Intraoperative Period; D000077222:Limonene; D008297:Male; D008875:Middle Aged; D039821:Monoterpenes / Q000627:therapeutic use*; D012852:Sinusitis / Q000188:drug therapy*; D013729:Terpenes / Q000627:therapeutic use*; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D003511:Cyclohexanols; D053138:Cyclohexenes; D005100:Expectorants; D039821:Monoterpenes; D013729:Terpenes; D000551:Ambroxol; D000077222:Limonene; D000077591:Eucalyptol