title: Influences of Geometric Configurations of Bypass Grafts on Hemodynamics in End-to-Side Anastomosis.
abstract: BACKGROUND
  Although considerable efforts have been made to improve the graft patency in coronary artery bypass surgery, the role of biomechanical factors remains underrecognized. The aim of this study is to investigate the influences of geometric configurations of the bypass graft on hemodynamic characteristics in relation to anastomosis.
  
  
  METHODS
  The Numerical analysis focuses on understanding the flow patterns for different values of inlet and distal diameters and graft angles. The Blood flow field is treated as a two-dimensional incompressible laminar flow. A finite volume method is adopted for discretization of the governing equations. The Carreau model is employed as a constitutive equation for blood. In an attempt to obtain the optimal aorto-coronary bypass conditions, the blood flow characteristics are analyzed using in vitro models of the end-to-side anastomotic angles of 45°, 60° and 90°. To find the optimal graft configurations, the mass flow rates at the outlets of the four models are compared quantitatively.
  
  
  RESULTS
  This study finds that Model 3, whose bypass diameter is the same as the inlet diameter of the stenosed coronary artery, delivers the largest amount of blood and the least pressure drop along the arteries.
  
  
  CONCLUSIONS
  Biomechanical factors are speculated to contribute to the graft patency in coronary artery bypass grafting.
authors.affiliation: Deptartment of Thoracic and Cardiovascular Surgery, Seoul National University Boramae Hospital, Korea.
authors.forename: Jae-Sung
authors.initials: JS
authors.lastname: Choi
authors.forename: Sung Chul
authors.initials: SC
authors.lastname: Hong
authors.forename: Hyuck Moon
authors.initials: HM
authors.lastname: Kwon
authors.forename: Sang-Ho
authors.initials: SH
authors.lastname: Suh
authors.forename: Jeong Sang
authors.initials: JS
authors.lastname: Lee