title: [Japanese HIV-infected men who have sex with men screened for anal intraepithelial neoplasia].
abstract: The prevalence of and the risk factors for abnormal anal cytology among Japanese men who have sex with men (MSM) who have human immunodeficiency virus (HIV) infection have not been fully investigated up to now. We conducted a nested case-control study of 81 HIV-infected Japanese MSM treated with antiretroviral therapy at a sexuality minority affirmative clinic between April 2010 and March 2011. Results showed that 41 (50.6%) of the 81 had normal anal cytology, 13 (16.0%) atypical squamous cells, 24 (29.6%) low-grade squamous intraepithelial lesions, and 3 (3.7%) high-grade squamous intraepithelial lesions. No carcinoma cases were seen. Multivariate analysis showed abnormal anal cytology to be associated with a history of genital condyloma (OR 4.19, p = .021). We concluded that abnormal anal cytology was common among HIV-infected Japanese MSM. Effective screening and management should be planned for precancerous anal lesions.
authors.affiliation: Shirakaba Clinic.
authors.forename: Ichiro
authors.initials: I
authors.lastname: Itoda
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Kitamura
mesh_terms: D000328:Adult; D001005:Anus Neoplasms / Q000453:epidemiology* / Q000209:etiology; D044466:Asian People; D002278:Carcinoma in Situ / Q000453:epidemiology* / Q000209:etiology; D016022:Case-Control Studies; D015658:HIV Infections / Q000150:complications*; D006716:Homosexuality; D006801:Humans; D008297:Male; D015995:Prevalence; D012307:Risk Factors