title: Initial experience with polytetrafluoroethylene leaflet extensions for aortic valve repair.
abstract: OBJECTIVE
  The purpose of this study is to evaluate our initial experience with aortic valve repair using polytetraflouroethylene (PTFE) leaflet extensions in congenital valvular disease.
  
  
  METHODS
  From October 2008 through February 2011, 13 patients underwent aortic valvuloplasty by PTFE leaflet extensions. All valves were repaired in a tri-leaflet configuration using PTFE leaflet extensions. The median age at operation was 14 years (1.8-19.7 years) and the median weight was 58 kg (9.5-86 kg). Previous interventions included balloon valvuloplasty in two patients, aortic valvuloplasty in one and coarctation repair in one patient. Eight (73%) patients had combined aortic stenosis and insufficiency, three (23%) had isolated insufficiency and two (15%) had stenosis only. In 10 (77%) patients, a bicuspid aortic valve was present.
  
  
  RESULTS
  The follow-up ranged from 2 to 30 months (mean follow-up 14.8 ± 9 months). At the latest echocardiography follow-up, six patients had none or trace aortic insufficiency, six patients had a mild aortic insufficiency and one patient had a mild-to-moderate insufficiency. The mean aortic insufficiency degree decreased from 1.8 ± 1.2 preoperatively to 0.8 ± 0.6 at the follow-up (P < 0.01). The mean gradient across the aortic valve decreased from 56 ± 40 mmHg preoperatively to 12 ± 13 mmHg at the follow-up (P < 0.0008). All patients are alive. There were no reoperations. The median hospital stay was 9 days (4-21 days).
  
  
  CONCLUSIONS
  The use of PTFE leaflet extensions is an effective technique for aortic valve reconstruction in congenital valvular disease. Long-term follow-up is necessary to assess the durability of this type of repair.
authors.affiliation: National Institute of Cardiovascular Disease, Childrens Heart Centre Slovakia, Bratislava, Slovakia. nosal@dkc-sr.sk
authors.forename: Matej
authors.initials: M
authors.lastname: Nosál'
authors.forename: Rudolf
authors.initials: R
authors.lastname: Poruban
authors.forename: Pavel
authors.initials: P
authors.lastname: Valentík
authors.forename: Michal
authors.initials: M
authors.lastname: Šagát
authors.forename: Aref Seif
authors.initials: AS
authors.lastname: Nagi
authors.forename: Andrea
authors.initials: A
authors.lastname: Kántorová
mesh_terms: D000293:Adolescent; D001021:Aortic Valve / Q000601:surgery*; D001022:Aortic Valve Insufficiency / Q000151:congenital / Q000601:surgery*; D001024:Aortic Valve Stenosis / Q000151:congenital / Q000601:surgery*; D002648:Child; D002675:Child, Preschool; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D011138:Polytetrafluoroethylene; D019736:Prostheses and Implants; D012189:Retrospective Studies; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D011138:Polytetrafluoroethylene