title: [Efficacy of a dentifrice containing 5% potassium nitrate on dental hypersensitivity].
abstract: OBJECTIVE
  To evaluate the efficacy of a dentifrice containing 5% potassium nitrate (test) on dental hypersensitivity compared with the fluoride dentifrice (control) over a 4-week period.
  
  
  METHODS
  The study design was a randomized ,double-blinded ,controlled clinical trial. 63 subjects were randomly divided into 2 groups, with 31 were given a 5% potassium nitrate dentifrice (experimental group) and the other 32 given a fluoride dentifrice (control group). Both groups were instructed to brush their teeth twice a day. An air blast stimulus was used to measure the degree of pain using a VAS scale. The data were analysed by the nonparametric Mann-Whitney U test and Wilcoxon-test with SPSS13.0 software package.
  
  
  RESULTS
  The VAS (baseline=68.29±8.263, 4-week=31.71±6.378) was significantly reduced over the 4 weeks period in the experimental group (P<0.05). After 4 weeks, VAS in the experimental group was significantly lower than that in the control group(P<0.05).
  
  
  CONCLUSIONS
  The study demonstrates that the dentifrice containing 5% potassium nitrate effectively reduces dental hypersensitivity.
authors.affiliation: Department of dentistry, People's Hospital Affiliated to Quanzhou Medical College, Quanzhou 362000, Fujian Province, China. 18965869766@189.com
authors.forename: Wen-jie
authors.initials: WJ
authors.lastname: Zhuang
authors.forename: Dong
authors.initials: D
authors.lastname: Cao
mesh_terms: D003802:Dentifrices; D003807:Dentin Sensitivity; D004311:Double-Blind Method; D004338:Drug Combinations; D005459:Fluorides; D006801:Humans; D009566:Nitrates; D010710:Phosphates; D017680:Potassium Compounds; D012969:Sodium Fluoride
chemical_list: D003802:Dentifrices; D004338:Drug Combinations; D009566:Nitrates; D010710:Phosphates; D017680:Potassium Compounds; C012980:fluorophosphate; D012969:Sodium Fluoride; D005459:Fluorides; C023844:potassium nitrate