title: Cleidocranial dysplasia presenting with retained deciduous teeth in a 15-year-old girl: a case report.
abstract: BACKGROUND
  Cleidocranial dysplasia is a rare congenital defect of autosomal dominant inheritance caused by mutations in the Cbfa1 gene, also called Runx2, located on the short arm of chromosome 6. It primarily affects bones which undergo intramembranous ossification. This condition is of clinical significance to dentistry due to the involvement of the facial bones, altered eruption patterns and multiple supernumerary teeth.
  
  
  METHODS
  Our patient, a 15-year-old Indian girl, presented with the typical features of prolonged retention of deciduous dentition and delayed eruption of permanent teeth, that is, mandibular prognathism along with other skeletal abnormalities like shrugged shoulder and the absence of clavicles. A multidisciplinary approach was followed, comprising orthodontic, surgical and pedodontic teams for management.
  
  
  CONCLUSIONS
  Successful treatment of such a case lies in a holistic approach that takes care of all aspects, including the primary pathology, the deformity itself and even the psychological angle.
authors.affiliation: Pedodontics and Preventive Dentistry, Rajarajeswari Dental College and Hospital, Bangalore- 560074, Karnataka, India. shaanrathna@gmail.com.
authors.forename: Nagarathna
authors.initials: N
authors.lastname: C
authors.forename: Bethur Siddaiah
authors.initials: BS
authors.lastname: Shakuntala
authors.forename: Somy
authors.initials: S
authors.lastname: Mathew
authors.forename: Navin Hadadi
authors.initials: NH
authors.lastname: Krishnamurthy
authors.forename: Ratna
authors.initials: R
authors.lastname: Yumkham