title: De novo aneurysm after treatment of glioblastoma.
abstract: A rare case of spontaneous subarachnoid hemorrhage from newly developed cerebral aneurysm in glioblastoma patient is presented. A 57-year-old man was presented with headache and memory impairment. On the magnetic resonance image and the magnetic resonance angiography, a large enhancing mass was found at right frontal subcortex and intracranial aneurysm was not found. The mass was removed subtotally and revealed as glioblastoma. He took concurrent PCV chemotherapy and radiation therapy, but the mass recurred one month later after radiotherapy. He was then treated with temozolomide for 7 cycles. Three months after the completion of temozolomide therapy, he suffered from a subarachnoid hemorrhage due to a rupture of a small de novo aneurysm at distal anterior cerebral artery. He underwent an aneurysm clipping and discharged without neurologic complication.
authors.affiliation: Department of Neurosurgery, Incheon St. Mary's Hospital, The Catholic University of Korea, College of Medicine, Incheon, Korea.
authors.forename: Wan-Soo
authors.initials: WS
authors.lastname: Yoon
authors.forename: Kwan-Sung
authors.initials: KS
authors.lastname: Lee
authors.forename: Sin-Soo
authors.initials: SS
authors.lastname: Jeun
authors.forename: Yong-Kil
authors.initials: YK
authors.lastname: Hong