title: Mini-laparotomy versus vaginal surgery for class II-III obese patients with early-stage endometrial cancer.
abstract: OBJECTIVE
  To compare minilaparotomic and vaginal surgery in selected obese patients with early-stage endometrial cancer at high surgical risk.
  
  
  METHODS
  Data of 37 consecutive class II-III obese patients submitted to minilaparotomic surgery were retrospectively reviewed. Thirty-seven women matched for demographic characteristics, BMI and stage of disease submitted to vaginal surgery in the same period comprised the control group.
  
  
  RESULTS
  No difference was observed concerning intra- and postoperative data among the two groups. The patients who were submitted to general anesthesia exhibited a larger use of supplemental drugs for pain control (p>0.01), a higher incidence of thromboembolic events (p>0.005) and a longer hospitalization (p>0.02). No statistical difference was observed in terms of pattern of recurrence, disease-free survival and overall survival between the two groups of patients.
  
  
  CONCLUSIONS
  Obese patients with endometrial cancer unfit for vaginal surgery can be safely managed through mini-laparotomy with the same surgical and oncological outcomes.
authors.affiliation: Dipartimento di Scienze per la Salute della Donna e del Bambino, Sezione di Ginecologia e Ostetricia, Policlinico di Careggi, Via Morgagni 85, 50134, Firenze, Italy. maxfambrini@libero.it
authors.forename: Massimiliano
authors.initials: M
authors.lastname: Fambrini
authors.forename: Annalisa
authors.initials: A
authors.lastname: Pieralli
authors.forename: Ubaldo
authors.initials: U
authors.lastname: Bitossi
authors.forename: Karin L
authors.initials: KL
authors.lastname: Andersson
authors.forename: Gianfranco
authors.initials: G
authors.lastname: Scarselli
authors.forename: Lorenzo
authors.initials: L
authors.lastname: Livi
authors.forename: Gianluigi
authors.initials: G
authors.lastname: Taddei
authors.forename: Mauro
authors.initials: M
authors.lastname: Marchionni
mesh_terms: D000368:Aged; D016889:Endometrial Neoplasms / Q000150:complications* / Q000473:pathology / Q000601:surgery*; D005260:Female; D013509:Gynecologic Surgical Procedures / Q000379:methods*; D006801:Humans; D007813:Laparotomy / Q000379:methods; D008875:Middle Aged; D009367:Neoplasm Staging; D009765:Obesity / Q000150:complications*; D012189:Retrospective Studies; D016896:Treatment Outcome