title: [Outcome after surgery preserving pharynx and larynx for cervical esophageal cancer].
abstract: OBJECTIVE
  To evaluate the long-term survival of multidisciplinary treatment based on thoracic surgery for cervical esophageal squamous cell carcinoma.
  
  
  METHODS
  The clinical characters and follow-up data of forty-one cervical esophageal cancer patients who accepted multidisciplinary treatment based on surgery with preservation of pharynx and larynx were retrospectively reviewed, and the long-term survival was compared with 480 non-cervical esophageal cancers who accepted surgery in the same period done by the same surgical team.
  
  
  RESULTS
  There were 28 males and 13 females with a mean age of 62 years old. In the cervical esophageal cancer group, 30 patients accepted neoadjuvant chemotherapy, 25 patients accepted adjuvant chemotherapy, and 21 patients accepted both. Six patients received postoperative radiation. Four patients underwent exploratory surgery alone, and 37 cases underwent radical surgery and cervical anastomosis. One case died during the perioperative period. The 1-, 3-, 5- and 8-year survival rates were 96.8%, 52.6%, 35.1%, and 35.1% in the 36 patients with cervical esophageal cancer who underwent radical surgery, and were 85.0%, 54.3%, 45.0%, and 36.7% respectively in the 457 non-cervical esophageal cancer patients. There was no significant difference between the cervical group and non-cervical group(P=0.91).
  
  
  CONCLUSIONS
  Cervical esophageal cancer should be treated in a multidisciplinary approach to obtain satisfactory long-term outcomes.
authors.affiliation: Department of Thoracic Surgery I, Beijing Cancer Hospital and Institute, Beijing, China.
authors.forename: Shao-hua
authors.initials: SH
authors.lastname: Ma
authors.forename: Bin
authors.initials: B
authors.lastname: Qin
authors.forename: Lu-yan
authors.initials: LY
authors.lastname: Shen
authors.forename: Zhen
authors.initials: Z
authors.lastname: Liang
authors.forename: Xiao-zhen
authors.initials: XZ
authors.lastname: Kang
authors.forename: Liang
authors.initials: L
authors.lastname: Dai
authors.forename: Ke-neng
authors.initials: KN
authors.lastname: Chen
mesh_terms: D003131:Combined Modality Therapy; D004938:Esophageal Neoplasms / Q000601:surgery*; D016629:Esophagectomy / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007830:Larynx / Q000601:surgery; D008297:Male; D008875:Middle Aged; D010614:Pharynx / Q000601:surgery; D012189:Retrospective Studies; D016896:Treatment Outcome