title: Introduction to membrane proteins.
abstract: Membrane proteins (MPs) mediate important physiological processes for the cell via extracellular and intracellular interactions. To better understand the biochemical and structural bases of these interactions, well-characterized preparations of purified MPs are required. This introduction reviews common problems encountered in MP preparation.
authors.affiliation: Biologics Research, Biotechnology Center of Excellence, Janssen Research & Development, Radnor, Pennsylvania.
authors.forename: Mark L
authors.initials: ML
authors.lastname: Chiu
mesh_terms: D020816:Amino Acid Motifs; D002462:Cell Membrane / Q000737:chemistry*; D003902:Detergents / Q000737:chemistry; D006801:Humans; D008055:Lipids / Q000737:chemistry; D008565:Membrane Proteins / Q000032:analysis* / Q000737:chemistry* / Q000302:isolation & purification; D015202:Protein Engineering / Q000379:methods; D017510:Protein Folding; D011499:Protein Processing, Post-Translational; D055550:Protein Stability; D017433:Protein Structure, Secondary; D012995:Solubility; D013329:Structure-Activity Relationship
chemical_list: D003902:Detergents; D008055:Lipids; D008565:Membrane Proteins