title: Extracorporeal therapy in sepsis: are we there yet?
abstract: The role of extracorporeal therapies (ECTs) in sepsis is unclear and is a strongly debated topic in critical-care medicine. Unfortunately, much of this debate arises because we lack a clear understanding of what defines the stage and severity of the disease, and the pivotal pathophysiological events dictating outcomes. In the absence of this knowledge, ECTs remain among a large group of therapies with high promise but unproven efficacy.
authors.affiliation: Division of Nephrology, University of Arkansas for Medical Sciences, 4301 W. Markham Street Slot 501, Little Rock, Arkansas 72205, USA. amshukla@uams.edu
authors.forename: Ashutosh M
authors.initials: AM
authors.lastname: Shukla
mesh_terms: D000818:Animals; D016207:Cytokines / Q000097:blood*; D006440:Hemofiltration; D008297:Male; D018805:Sepsis / Q000097:blood* / Q000628:therapy*
chemical_list: D016207:Cytokines