title: Carotid baroreceptor reaction after stenting in 2 locations of carotid bulb lesions of different embryologic origin.
abstract: OBJECTIVE
  The carotid bulb is innervated by the sinus nerve of Hering, a branch of the glossopharyngeal nerve, derived from the third pharyngeal arch. The aim of this study was to determine the frequency, predictors, and outcome of the carotid BR after carotid stent placement according to the location of the plaque lesion.
  
  
  METHODS
  Atherosclerotic carotid plaques of apical versus body lesions were prospectively analyzed in 95 consecutive patients who underwent carotid stent placement. Patients with hypertension after stent placement were excluded, and transient (<3 hours) and prolonged (3-24 hours) BR, together with AEs such as strokes and death, were assessed in the 2 lesion locations (apical versus body). Other factors known to affect the carotid baroreceptor were also investigated, and the results were analyzed by χ(2) or Mann-Whitney U tests.
  
  
  RESULTS
  Transient BR occurred in 30% of apical lesions in contrast to 70% of body lesions (P = .001). Transient BR showed a significant relationship to lesion location (P = .001), occurring most frequently in body lesions, and to the distance of maximum stenosis from the ICA ostium (P = .001). Hyperperfusion and AE rates (P = .076) in 1 month occurred more frequently in apical lesions.
  
  
  CONCLUSIONS
  The frequency of transient BR after carotid stent placement was lower in the apical region of the carotid bulb. Different cardiovascular disturbances after carotid stent placement can be attributed to anatomically different areas of the carotid bulb.
authors.affiliation: Department of Radiology, Asan Medical Center, University of Ulsan, College of Medicine, 86 Asanbyeongwon-Gil, Songpa-Gu, Seoul 138-736, Korea. dcsuh@amc.seoul.kr
authors.forename: D C
authors.initials: DC
authors.lastname: Suh
authors.forename: J L
authors.initials: JL
authors.lastname: Kim
authors.forename: E H
authors.initials: EH
authors.lastname: Kim
authors.forename: J K
authors.initials: JK
authors.lastname: Kim
authors.forename: J-H
authors.initials: JH
authors.lastname: Shin
authors.forename: D H
authors.initials: DH
authors.lastname: Hyun
authors.forename: H Y
authors.initials: HY
authors.lastname: Lee
authors.forename: D H
authors.initials: DH
authors.lastname: Lee
authors.forename: J S
authors.initials: JS
authors.lastname: Kim
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D017704:Baroreflex; D001794:Blood Pressure; D001807:Blood Vessel Prosthesis; D002339:Carotid Arteries / Q000196:embryology / Q000503:physiopathology* / Q000601:surgery*; D002340:Carotid Artery Diseases / Q000196:embryology / Q000503:physiopathology* / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011311:Pressoreceptors / Q000196:embryology / Q000503:physiopathology*; D015607:Stents