title: Comprehensive ultrasound diagnosis for intraductal spread of primary breast cancer.
abstract: BACKGROUND
  The current capacity of preoperative ultrasound examinations to estimate the intraductal spread of primary breast cancer was evaluated. The current ultrasound examination has three modes, B-mode, vascularity, and elastography, and this study evaluated this comprehensive ultrasound examination.
  
  
  METHODS
  Of the patients undergoing breast cancer surgery for a breast mass at our department between April 2010 and March 2011, we evaluated 99 in whom breast-conserving surgery was scheduled, and performed preoperative ultrasounds and stored the digital ultrasound images and pathology data. ACR BI-RADS(®)-US lexicon elastography for the main mass and peri-tumoral ductal lesions (PTDL, defined in main sentence), and the vascularity and elasticity pattern (defined in main sentence) were evaluated.
  
  
  RESULTS
  A cut end-negative resection at the first procedure after ultrasound estimation was achieved in 76.7%, and the breast was conserved by an additional resection with a negative margin in 90.6%. Shadowing of mass posterior acoustic features tends to indicate cut end-negative results significantly. There was a statistical difference between "vascularity in PTDL" and "elasticity pattern of PTDL".
  
  
  CONCLUSIONS
  Using the recent comprehensive ultrasound examination with vascularity and elastography was useful for the preoperative estimation of intraductal spread of primary breast cancer in our retrospective study.
authors.affiliation: Department of Breast and Thyroid Surgery, Kawasaki Medical School, 577 Matsushima, Kurashiki, Okayama 701-0192, Japan. urbandoc@med.kawasaki-m.ac.jp
authors.forename: Kazutaka
authors.initials: K
authors.lastname: Nakashima
authors.forename: Takuya
authors.initials: T
authors.lastname: Moriya
mesh_terms: D001943:Breast Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000000981:diagnostic imaging* / Q000473:pathology; D054459:Elasticity Imaging Techniques; D005260:Female; D006801:Humans; D015412:Mastectomy, Segmental; D057234:Preoperative Period; D012189:Retrospective Studies; D016217:Ultrasonography, Mammary