title: Marked response to both S-1 and pemetrexed in a patient with echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase-positive lung adenocarcinoma.
authors.forename: Hiroyasu
authors.initials: H
authors.lastname: Kaneda
authors.forename: Isamu
authors.initials: I
authors.lastname: Okamoto
authors.forename: Kazuko
authors.initials: K
authors.lastname: Sakai
authors.forename: Junko
authors.initials: J
authors.lastname: Tanizaki
authors.forename: Masayuki
authors.initials: M
authors.lastname: Takeda
authors.forename: Kazuto
authors.initials: K
authors.lastname: Nishio
authors.forename: Kazuhiko
authors.initials: K
authors.lastname: Nakagawa
mesh_terms: D000230:Adenocarcinoma / Q000737:chemistry* / Q000175:diagnosis / Q000188:drug therapy*; D000077192:Adenocarcinoma of Lung; D000328:Adult; D000077548:Anaplastic Lymphoma Kinase; D000964:Antimetabolites, Antineoplastic / Q000627:therapeutic use*; D014408:Biomarkers, Tumor / Q000032:analysis*; D018797:Cell Cycle Proteins / Q000032:analysis*; D004338:Drug Combinations; D005971:Glutamates / Q000627:therapeutic use*; D006147:Guanine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D006801:Humans; D008175:Lung Neoplasms / Q000737:chemistry* / Q000175:diagnosis / Q000188:drug therapy*; D008297:Male; D008869:Microtubule-Associated Proteins / Q000032:analysis*; D010094:Oxonic Acid / Q000627:therapeutic use*; D000068437:Pemetrexed; D049268:Positron-Emission Tomography; D020794:Receptor Protein-Tyrosine Kinases / Q000032:analysis*; D012697:Serine Endopeptidases / Q000032:analysis*; D005641:Tegafur / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D000964:Antimetabolites, Antineoplastic; D014408:Biomarkers, Tumor; D018797:Cell Cycle Proteins; D004338:Drug Combinations; D005971:Glutamates; D008869:Microtubule-Associated Proteins; D000068437:Pemetrexed; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid; D006147:Guanine; C000626173:ALK protein, human; D000077548:Anaplastic Lymphoma Kinase; D020794:Receptor Protein-Tyrosine Kinases; C415585:EML4 protein, human; D012697:Serine Endopeptidases