title: Diverse mobilized class 1 integrons are common in the chromosomes of pathogenic Pseudomonas aeruginosa clinical isolates.
abstract: Eleven clinical class 1 integron-containing Pseudomonas aeruginosa isolates from Australia and Uruguay were investigated for the genomic locations of these elements. Several novel class 1 integrons/transposons were found in at least four distinct locations in the chromosome, including genomic islands. These elements seem to be undergoing successful dispersal by lateral gene transfer since integrons were identified across several lineages and more than one clonal line.
authors.affiliation: The ithree Institute, University of Technology, Sydney, Australia.
authors.forename: Elena
authors.initials: E
authors.lastname: Martinez
authors.forename: Carolina
authors.initials: C
authors.lastname: Marquez
authors.forename: Ana
authors.initials: A
authors.lastname: Ingold
authors.forename: John
authors.initials: J
authors.lastname: Merlino
authors.forename: Steven P
authors.initials: SP
authors.lastname: Djordjevic
authors.forename: H W
authors.initials: HW
authors.lastname: Stokes
authors.forename: Piklu Roy
authors.initials: PR
authors.lastname: Chowdhury
mesh_terms: D001315:Australia; D002876:Chromosomes, Bacterial / Q000235:genetics*; D024881:Drug Resistance, Bacterial / Q000235:genetics; D024901:Drug Resistance, Multiple, Bacterial / Q000187:drug effects; D016521:Electrophoresis, Gel, Pulsed-Field; D005798:Genes, Bacterial / Q000235:genetics; D044404:Genomic Islands / Q000235:genetics; D032023:Integrons / Q000235:genetics*; D008826:Microbial Sensitivity Tests; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D011552:Pseudomonas Infections / Q000235:genetics / Q000382:microbiology*; D011550:Pseudomonas aeruginosa / Q000235:genetics*; D014583:Uruguay