title: [Benefit of primary saturational biopsy in detection of localized prostatic cancer after radical prostatectomy].
abstract: We studied diagnostic potential of saturational technique of prostatic biopsy in 1018 males with suspected prostatic cancer (PC). Primary transrectal multifocal prostatic biopsy under ultrasound control was made in all the examinees including 453 procedures with use of saturational technique. The age of the patients varied from 43 to 77 years (median 60 years). A total of 159 patients with diagnosed prostatic cancer have undergone retropubic radical prostatectomy. Saturational biopsy has detected prostatic cancer in 35.1% cases. This technique was employed in hard for PC diagnosis parameters: age median 60 years, PSA 11.9 ng/ml, PSA density 0.23 ng/ml/cm3, prostatic volume 59.7 cm3. The above variant of biopsy detects the highest proportion of localized PC stages, minimal incidence of positive surgical margin, perineural and perivascular invasions, minimal score by Glison/s scale. Thus, the saturational technique of biopsy can be the method of choice in patients under 65 years of age, in a PSA level under 10 ng/ml, PSA density under 0.25 ng/ml/sm3 and prostatic volume over 60 cm3.
authors.forename: E I
authors.initials: EI
authors.lastname: Veliev
authors.forename: A
authors.initials: A
authors.lastname: Obeĭd
authors.forename: A B
authors.initials: AB
authors.lastname: Bogdanov
mesh_terms: D000328:Adult; D000368:Aged; D001706:Biopsy; D006801:Humans; D008297:Male; D008875:Middle Aged; D009929:Organ Size; D017430:Prostate-Specific Antigen / Q000097:blood; D011468:Prostatectomy; D011471:Prostatic Neoplasms / Q000097:blood / Q000473:pathology* / Q000601:surgery*
chemical_list: D017430:Prostate-Specific Antigen