title: [Complete mesocolic excision versus traditional radical resection in colon cancer].
abstract: OBJECTIVE
  To compare the short-term efficacy and safety between complete mesocolic excision (CME) and traditional radical resection in colon cancer.
  
  
  METHODS
  Between January 2008 and August 2011, 92 patients undergoing elective open surgery for colon were included in the study. CME was performed in 54 patients in the period from November 2009 to August 2011. The other 38 patients underwent traditional radical resection from January 2008 to October 2009. Short-term outcomes were compared between the patients of two different time periods.
  
  
  RESULTS
  Lymph nodes retrieved in the CME group (22.2 ± 8.0) were significant more than that in the control group (18.6 ± 4.7)(P<0.05). In patients with stage III cancer, CME group was associated with higher lymph node counts (23.8 ± 7.6 vs. 16.7 ± 3.6, P<0.01), however, there were no significant differences for those with stage I and stage II cancer (P>0.05). The number of positive lymph nodes and metastatic lymph node ratio (LNR) for stage III patients in two groups were not significantly different (P>0.05). There were no differences in operation time, time to first bowel movement, hospital stay, and postoperative complications between the two groups (P>0.05). However, intraoperative blood loss in the CME group was significantly reduced (median, 100 vs. 115 ml, P<0.05).
  
  
  CONCLUSIONS
  CME can achieve en-bloc resection of the tumor and mesocolon, and have optimal lymph nodes harvest. Despite wider resection extent with CME technique, the surgical risk and postoperative complications are not increased and the short-term efficacy is good.
authors.affiliation: Department of Gastrointestinal Surgery, Peking University People's Hospital, Beijing, China.
authors.forename: Zhi-dong
authors.initials: ZD
authors.lastname: Gao
authors.forename: Ying-jiang
authors.initials: YJ
authors.lastname: Ye
authors.forename: Shan
authors.initials: S
authors.lastname: Wang
authors.forename: Xiao-dong
authors.initials: XD
authors.lastname: Yang
authors.forename: Mu-jun
authors.initials: MJ
authors.lastname: Yin
authors.forename: Bin
authors.initials: B
authors.lastname: Liang
authors.forename: Ke-wei
authors.initials: KW
authors.lastname: Jiang
authors.forename: Qi-wei
authors.initials: QW
authors.lastname: Xie
authors.forename: Peng
authors.initials: P
authors.lastname: Guo
mesh_terms: D003082:Colectomy / Q000379:methods; D003110:Colonic Neoplasms / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008646:Mesocolon / Q000601:surgery*; D012189:Retrospective Studies; D016896:Treatment Outcome