title: Structural modification of the gastrointestinal epithelium during immune-dependent granulomatosis.
abstract: We present results of pathomorphological study of the mucosa epithelium in various parts of the gastrointestinal tract in Crohn's disease. Particular attention was paid to structural transformation of epithelial cells. Barrier dysfunction of the gastrointestinal mucosa was shown to be one of the major pathogenetic factors for Crohn's disease.
authors.affiliation: Institute of Regional Pathology and Pathomorphology, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk, Russia. pathol@soramn.ru
authors.forename: D L
authors.initials: DL
authors.lastname: Nepomnyashchikh
authors.forename: V A
authors.initials: VA
authors.lastname: Burkovskaya
authors.forename: S V
authors.initials: SV
authors.lastname: Aidagulova
authors.forename: M A
authors.initials: MA
authors.lastname: Bakarev
authors.forename: O A
authors.initials: OA
authors.lastname: Postnikova
authors.forename: V I
authors.initials: VI
authors.lastname: Kapustina
authors.forename: Zh V
authors.initials: ZhV
authors.lastname: Nokhrina
authors.forename: E V
authors.initials: EV
authors.lastname: Vinogradova
mesh_terms: D000293:Adolescent; D000328:Adult; D003424:Crohn Disease / Q000473:pathology* / Q000503:physiopathology; D004847:Epithelial Cells / Q000473:pathology; D005260:Female; D005753:Gastric Mucosa / Q000473:pathology* / Q000503:physiopathology; D041981:Gastrointestinal Tract / Q000473:pathology* / Q000503:physiopathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D055815:Young Adult