title: Annual banned-substance review: analytical approaches in human sports drug testing.
abstract: International anti-doping efforts are harmonized and regulated under the umbrella of the World Anti-Doping Code and the corresponding Prohibited List, issued annually by the World Anti-Doping Agency (WADA). The necessity for a frequent and timely update of the Prohibited List (as the result of a comprehensive consultation process and subsequent consensual agreement by expert panels regarding substances and methods of performance manipulation in sports) is due to the constantly growing market of emerging therapeutics and thus new options for cheating athletes to illicitly enhance performance. In addition, 'tailor-made' substances arguably designed to undermine sports drug testing procedures are considered and the potential of established drugs to represent a doping substance is revisited in light of recently generated information. The purpose of the annual banned substance review is to support doping controls by reporting emerging and advancing methods dedicated to the detection of known and recently outlawed substances. This review surveys new and/or enhanced procedures and techniques of doping analysis together with information relevant to doping controls that has been published in the literature between October 2010 and September 2011.
authors.affiliation: Center for Preventive Doping Research-Institute of Biochemistry, German Sport University Cologne, Germany. thevis@dshs-koeln.de
authors.forename: Mario
authors.initials: M
authors.lastname: Thevis
authors.forename: Tiia
authors.initials: T
authors.lastname: Kuuranne
authors.forename: Hans
authors.initials: H
authors.lastname: Geyer
authors.forename: Wilhelm
authors.initials: W
authors.lastname: Schänzer
mesh_terms: D004300:Doping in Sports / Q000331:legislation & jurisprudence; D004335:Drug and Narcotic Control / Q000331:legislation & jurisprudence; D006801:Humans; D058573:Performance-Enhancing Substances / Q000032:analysis* / Q000145:classification; D015203:Reproducibility of Results; D015813:Substance Abuse Detection / Q000331:legislation & jurisprudence / Q000379:methods*; D009626:Terminology as Topic
chemical_list: D058573:Performance-Enhancing Substances