title: A case of pseudo-xanthoma elasticum presenting with ischaemic claudication.
abstract: A 37-year-old man presented with symptoms of intermittent claudication. Investigations revealed atypical calf vessel disease but no obvious aetiology. Ten years later he re-presented with worsening symptoms. CT angiography confirmed the atypical pattern of lower limb arterial disease but also noted calcification of the renal parenchyma, myocardium and scrotum. A diagnosis of pseudo-xanthoma elasticum was confirmed by skin biopsy. Pseudo-xanthoma elasticum is a rare condition that presents infrequently to vascular surgeons. Early recognition should prompt aggressive risk factor management to slow accelerated atherosclerosis. Clinicians should be aware of the clinical features of this condition to allow early diagnosis.
authors.affiliation: Department of Vascular Surgery, Southampton University Hospitals NHS Trust, Southampton SO16 6YD, UK. chris.lamb@cantab.net
authors.forename: C M
authors.initials: CM
authors.lastname: Lamb
authors.forename: R A
authors.initials: RA
authors.lastname: Johns
authors.forename: P J
authors.initials: PJ
authors.lastname: Gallagher
authors.forename: A
authors.initials: A
authors.lastname: Odurny
authors.forename: C P
authors.initials: CP
authors.lastname: Shearman
mesh_terms: D000328:Adult; D006801:Humans; D007383:Intermittent Claudication / Q000209:etiology*; D008297:Male; D011561:Pseudoxanthoma Elasticum / Q000150:complications* / Q000175:diagnosis*