title: Hypertrophic osteoarthropathy with acro-osteolysis in a patient with primary pulmonary hypertension.
abstract: Hypertrophic osteoarthropathy is an entity characterized by a triad of periostitis of long bones, clubbing and arthritis. Radiologically there are two patterns, one characterized by new bone formation which predominates in patients with pulmonary disease, and another by acro-osteolysis that is most frequently associated with congenital heart disease. We report the case of a 30-year-old man diagnosed with primary pulmonary hypertension for two years, developing hypertrophic osteoarthropathy with a mixed radiological pattern.
authors.affiliation: Servicio de Reumatología, Hospital Universitario Ramón y Cajal, Madrid, Spain. albertosifuentesg@gmail.com
authors.forename: Walter Alberto
authors.initials: WA
authors.lastname: Sifuentes Giraldo
authors.forename: María
authors.initials: M
authors.lastname: Ahijón Lana
authors.forename: Ignacio
authors.initials: I
authors.lastname: Gallego Rivera
authors.forename: Francisco Javier
authors.initials: FJ
authors.lastname: Bachiller Corral
authors.forename: María Luz
authors.initials: ML
authors.lastname: Gámir Gámir
mesh_terms: D000328:Adult; D001323:Autoantibodies / Q000097:blood; D001324:Autoantigens / Q000276:immunology; D002118:Calcium / Q000627:therapeutic use; D002956:Citrulline / Q000032:analysis; D004164:Diphosphonates / Q000627:therapeutic use; D050276:Hand Bones / Q000000981:diagnostic imaging; D006801:Humans; D006976:Hypertension, Pulmonary / Q000150:complications*; D007093:Imidazoles / Q000627:therapeutic use; D008297:Male; D010005:Osteoarthropathy, Secondary Hypertrophic / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology*; D010014:Osteolysis / Q000000981:diagnostic imaging / Q000209:etiology; D010455:Peptides / Q000737:chemistry / Q000276:immunology; D011282:Pregnenediones / Q000627:therapeutic use; D011859:Radiography; D011884:Radius / Q000000981:diagnostic imaging; D014807:Vitamin D / Q000627:therapeutic use; D014955:Wrist Joint / Q000000981:diagnostic imaging; D000077211:Zoledronic Acid
chemical_list: D001323:Autoantibodies; D001324:Autoantigens; D004164:Diphosphonates; D007093:Imidazoles; D010455:Peptides; D011282:Pregnenediones; D014807:Vitamin D; D002956:Citrulline; D000077211:Zoledronic Acid; C021988:deflazacort; D002118:Calcium