title: [Alternate-day oral tadalafil for erectile dysfunction with no successful intercourse at the baseline].
abstract: OBJECTIVE
  To summarize the experience in the treatment of erectile dysfunction (ED) with no successful intercourse at the baseline with tadalafil.
  
  
  METHODS
  We retrospectively analyzed 21 cases of ED with no successful intercourse at the baseline treated with tadalafil on alternate days combined with sex guidance.
  
  
  RESULTS
  After 4 weeks of tadalafil treatment, 19 of the patients achieved successful sexual intercourse, and the IIEF-5 score was remarkably improved as compared with pre-medication (3.24 +/- 1.55 vs 18.95 +/- 3.02, P<0.0001). Mild adverse reactions were observed in 6 cases, including 2 cases of mild headache and 4 cases of facial blush.
  
  
  CONCLUSIONS
  Tadalafil on alternate days combined with sex guidance can significantly improve ED with no successful intercourse at the baseline.
authors.affiliation: Center of Reproductive Medicine, Shengjing Hospital, China Medical University, Shenyang, Liaoning 110003, China.
authors.forename: Qiang
authors.initials: Q
authors.lastname: Du
authors.forename: Zheng-tao
authors.initials: ZT
authors.lastname: Li
authors.forename: Xin
authors.initials: X
authors.lastname: Xing
authors.forename: Bo-Chen
authors.initials: BC
authors.lastname: Pan
authors.forename: Yong-sheng
authors.initials: YS
authors.lastname: Song
authors.forename: Bin
authors.initials: B
authors.lastname: Wu
mesh_terms: D000328:Adult; D002243:Carbolines / Q000008:administration & dosage / Q000627:therapeutic use*; D003075:Coitus; D007172:Erectile Dysfunction / Q000188:drug therapy* / Q000503:physiopathology; D006801:Humans; D008297:Male; D012189:Retrospective Studies; D000068581:Tadalafil; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D002243:Carbolines; D000068581:Tadalafil