title: Ultrafast inverse imaging techniques for fMRI.
abstract: Inverse imaging (InI) supercharges the sampling rate of traditional functional MRI 10-100 fold at a cost of a moderate reduction in spatial resolution. The technique is inspired by similarities between multi-sensor magnetoencephalography (MEG) and highly parallel radio-frequency (RF) MRI detector arrays. Using presently available 32-channel head coils at 3T, InI can be sampled at 10 Hz and provides about 5-mm cortical spatial resolution with whole-brain coverage. Here we discuss the present applications of InI, as well as potential future challenges and opportunities in further improving its spatiotemporal resolution and sensitivity. InI may become a helpful tool for clinicians and neuroscientists for revealing the complex dynamics of brain functions during task-related and resting states.
authors.affiliation: Institute of Biomedical Engineering, National Taiwan University, Taipei, Taiwan.
authors.forename: Fa-Hsuan
authors.initials: FH
authors.lastname: Lin
authors.forename: Kevin W K
authors.initials: KW
authors.lastname: Tsai
authors.forename: Ying-Hua
authors.initials: YH
authors.lastname: Chu
authors.forename: Thomas
authors.initials: T
authors.lastname: Witzel
authors.forename: Aapo
authors.initials: A
authors.lastname: Nummenmaa
authors.forename: Tommi
authors.initials: T
authors.lastname: Raij
authors.forename: Jyrki
authors.initials: J
authors.lastname: Ahveninen
authors.forename: Wen-Jui
authors.initials: WJ
authors.lastname: Kuo
authors.forename: John W
authors.initials: JW
authors.lastname: Belliveau
mesh_terms: D001921:Brain / Q000502:physiology; D001931:Brain Mapping / Q000379:methods*; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D013997:Time Factors