title: PEG-mediated catalyst-free expeditious synthesis of polysubstituted anilines and benzenes via the reaction of malononitrile and β-ketoester derivatives in the presence of activated acetylenes.
abstract: Poly(ethylene glycol) (PEG) has been used as a sustainable, non-volatile, and environmentally friendly reaction solvent for synthesis of functionalized anilines and benzenes via the reaction of malononitrile and β-ketoester derivatives in the presence of activated acetylenes at 80° C. No additional solvent and catalyst are required.
authors.affiliation: Department of Chemistry, Sanandaj Branch, Islamic Azad University, Sanandaj, Iran. mohammadpiltan@yahoo.com
authors.forename: Mohammad
authors.initials: M
authors.lastname: Piltan
authors.forename: Loghman
authors.initials: L
authors.lastname: Moradi
authors.forename: Hiwa
authors.initials: H
authors.lastname: Salimi
authors.forename: Kiomars
authors.initials: K
authors.lastname: Zargoosh
authors.forename: Seyed Amir
authors.initials: SA
authors.lastname: Zarei
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D000814:Aniline Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D001554:Benzene / Q000138:chemical synthesis* / Q000737:chemistry; D020650:Combinatorial Chemistry Techniques; D004952:Esters / Q000737:chemistry*; D015394:Molecular Structure; D009570:Nitriles / Q000737:chemistry*; D011092:Polyethylene Glycols / Q000737:chemistry*
chemical_list: D000480:Alkynes; D000814:Aniline Compounds; D004952:Esters; D009570:Nitriles; D011092:Polyethylene Glycols; C000945:dicyanmethane; D001554:Benzene; C023650:aniline