title: Primary central nervous system B cell lymphoma with features intermediate between diffuse large B cell lymphoma and Burkitt lymphoma.
abstract: B cell lymphoma with features intermediate between diffuse large B cell lymphoma and Burkitt lymphoma (DLBCL/BL) is a new lymphoma entity which is recognized in the current World Health Organization (WHO) classification (2008). We report a case of a primary central nervous system lymphoma (PCNSL) with findings consistent with DLBCL/BL. It is characterized by a very aggressive clinical course, and a widespread multifocal involvement of the CNS. Our case shows that a DLBCL/BL can manifest in the CNS alone without any systemic involvement.
authors.affiliation: Department of Pathology, Mayo Clinic, Jacksonville, Florida 32224, USA.
authors.forename: Liuyan
authors.initials: L
authors.lastname: Jiang
authors.forename: Zhimin
authors.initials: Z
authors.lastname: Li
authors.forename: Laura E
authors.initials: LE
authors.lastname: Finn
authors.forename: David A
authors.initials: DA
authors.lastname: Personnet
authors.forename: Brandy
authors.initials: B
authors.lastname: Edenfield
authors.forename: James M
authors.initials: JM
authors.lastname: Foran
authors.forename: Kurt A
authors.initials: KA
authors.lastname: Jaeckle
authors.forename: Ronald
authors.initials: R
authors.lastname: Reimer
authors.forename: David M
authors.initials: DM
authors.lastname: Menke
authors.forename: Rhett P
authors.initials: RP
authors.lastname: Ketterling
authors.forename: Han W
authors.initials: HW
authors.lastname: Tun
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D016543:Central Nervous System Neoplasms / Q000235:genetics / Q000473:pathology* / Q000503:physiopathology*; D017809:Fatal Outcome; D019254:Genes, bcl-2; D006801:Humans; D007150:Immunohistochemistry; D017404:In Situ Hybridization, Fluorescence; D016393:Lymphoma, B-Cell / Q000235:genetics / Q000473:pathology* / Q000503:physiopathology*; D008297:Male; D009367:Neoplasm Staging; D016271:Proto-Oncogene Proteins c-myc / Q000235:genetics; D011878:Radiotherapy
chemical_list: D016271:Proto-Oncogene Proteins c-myc