title: Amino acids and our genetic code: a highly adaptive and interacting defense system.
abstract: Since the discovery of the genetic code, Mendel's heredity theory and Darwin's evolution theory, science believes that adaptations to the environment are processes in which the adaptation of the genes is a matter of probability, in which finally the specie will survive which is evolved by chance. We hypothesize that evolution and the adaptation of the genes is a well-organized fully adaptive system in which there is no rigidity of the genes. The dividing of the genes will take place in line with the environment to be expected, sensed through the mother. The encoding triplets can encode for more than one amino acid depending on the availability of the amino acids and the needed micronutrients. Those nutrients can cause disease but also prevent diseases, even cancer and auto immunity. In fact we hypothesize that auto immunity is an effective process of the organism to clear suboptimal proteins, formed due to amino acid and micronutrient deficiencies. Only when deficiencies sustain, disease will develop, otherwise the autoantibodies will function as all antibodies function, in a protective way. Furthermore, we hypothesize that essential amino acids are less important than nonessential amino acid (NEA). Species developed the ability to produce the nonessential amino acids themselves because they were not provided by food sufficiently. In contrast essential amino acids are widely available, without any evolutionary pressure. Since we can only produce small amounts of NEA and the availability in food can be reasoned to be too low they are still our main concern in amino acid availability. In conclusion, we hypothesize that increasing health will only be possible by improving our natural environment and living circumstances, not by changing the genes, since they are our last line of defense in surviving our environmental changes.
authors.affiliation: Regionaal Reuma Centrum, Maxima Medisch Centrum, Ds Th. Fliednerstraat 1, 5631 BM Eindhoven, The Netherlands. rhverheesen@onsbrabantnet.nl
authors.forename: R H
authors.initials: RH
authors.lastname: Verheesen
authors.forename: C M
authors.initials: CM
authors.lastname: Schweitzer
mesh_terms: D000220:Adaptation, Biological / Q000235:genetics*; D000596:Amino Acids / Q000235:genetics*; D015551:Autoimmunity / Q000235:genetics*; D019143:Evolution, Molecular; D005815:Genetic Code / Q000235:genetics*; D006801:Humans; D018977:Micronutrients / Q000235:genetics*; D008954:Models, Biological
chemical_list: D000596:Amino Acids; D018977:Micronutrients