title: Compositional studies: antioxidant and antidiabetic activities of Capparis decidua (Forsk.) Edgew.
abstract: Capparis decidua is one of the traditional remedies used for various medicinal treatments in Pakistan. This study presents the determination of proximate composition, amino acids, fatty acids, tocopherols, sterols, glucosinolate and phenolic content in extracts obtained from different aerial parts of C. decidua, as well as their antidiabetic and antioxidant activity. All examined extracts were prominently rich in phenolics and glucosinates, and they showed potent antidiabetic and antihemolytic activity. The present study could be helpful in developing medicinal preparations for the treatment of diabetes and related symptoms.
authors.affiliation: Department of Pharmacognosy, Research Institute of Pharmaceutical Sciences, University of Karachi, Karachi-75270, Pakistan. ahirzia@gmail.com
authors.forename: Muhammad
authors.initials: M
authors.lastname: Zia-Ul-Haq
authors.forename: Sanja
authors.initials: S
authors.lastname: Cavar
authors.forename: Mughal
authors.initials: M
authors.lastname: Qayum
authors.forename: Imran
authors.initials: I
authors.lastname: Imran
authors.forename: Vincenzo
authors.initials: V
authors.lastname: de Feo
mesh_terms: D000596:Amino Acids / Q000032:analysis; D000818:Animals; D000975:Antioxidants / Q000737:chemistry* / Q000494:pharmacology; D031484:Capparis / Q000737:chemistry*; D002417:Cattle; D004912:Erythrocytes / Q000187:drug effects; D005227:Fatty Acids / Q000032:analysis; D005961:Glucosinolates / Q000032:analysis; D006461:Hemolysis / Q000187:drug effects; D007004:Hypoglycemic Agents / Q000737:chemistry* / Q000494:pharmacology; D010084:Oxidation-Reduction; D010636:Phenols / Q000032:analysis; D010936:Plant Extracts / Q000737:chemistry* / Q000494:pharmacology; D013261:Sterols / Q000032:analysis; D024505:Tocopherols / Q000032:analysis
chemical_list: D000596:Amino Acids; D000975:Antioxidants; D005227:Fatty Acids; D005961:Glucosinolates; D007004:Hypoglycemic Agents; D010636:Phenols; D010936:Plant Extracts; D013261:Sterols; D024505:Tocopherols