title: How individual can personalized antiretroviral treatment be? Deep salvage in an HIV-1-infected patient.
abstract: We present an HIV-1-infected male (who is now 52 years old) with a multi-drug-resistant virus and discuss the considerations finally leading to an antiretroviral regimen resulting in long-term viral suppression and excellent immunological response in a deep salvage situation. Even in a desperate situation with high-level multi-class resistance, highly individual, personalized antiretroviral regimes can be tailor-made to achieve unexpected improvements in the health status of a patient.
authors.affiliation: Department of Gastroenterology, Hepatology and Infectious Diseases, Düsseldorf University Hospital, Düsseldorf, Germany. bjoern-erikole.jensen@med.uni-duesseldorf.de
authors.forename: Bjoern
authors.initials: B
authors.lastname: Jensen
authors.forename: Stefan
authors.initials: S
authors.lastname: Esser
authors.forename: Rolf
authors.initials: R
authors.lastname: Kaiser
authors.forename: Nadine
authors.initials: N
authors.lastname: Luebke
authors.forename: Dieter
authors.initials: D
authors.lastname: Häussinger
mesh_terms: D000328:Adult; D019380:Anti-HIV Agents / Q000008:administration & dosage*; D023241:Antiretroviral Therapy, Highly Active / Q000379:methods*; D018791:CD4 Lymphocyte Count; D024921:Drug Resistance, Multiple, Viral; D015658:HIV Infections / Q000188:drug therapy* / Q000821:virology; D015497:HIV-1 / Q000187:drug effects* / Q000302:isolation & purification; D006801:Humans; D008297:Male; D008875:Middle Aged; D016879:Salvage Therapy / Q000379:methods*; D016896:Treatment Outcome; D019562:Viral Load
chemical_list: D019380:Anti-HIV Agents