title: [McCune-Albright syndrome associated with diabetes mellitus].
abstract: McCune-Albright syndrome (MAS) consists of the triad of polyostotic fibrous dysplasia, cutaneous pigmentation, and multiple endocrine abnormalities. Type 1 diabetes mellitus is not included in MAS. We report the case of an 18-year-old girl who presented with McCune-Albright syndrome. The diagnosis was made by the presence of precocious puberty at the age of 6 years, cutaneous pigmentation, polyostotic fibrous dysplasia, and phosphate diabetes. Type 1 diabetes mellitus developed at the age of 16 years. We discuss this case, the relationship between type 1 diabetes mellitus and MAS, with a literature review.
authors.affiliation: Service endocrinologie diabétologie, hôpital La Rabta, Jabbari, 1007 Tunis, Tunisie. mm.chihaoui@planet.tn
authors.forename: M
authors.initials: M
authors.lastname: Chihaoui
authors.forename: N
authors.initials: N
authors.lastname: Hamza
authors.forename: F
authors.initials: F
authors.lastname: Lamine
authors.forename: S
authors.initials: S
authors.lastname: Jabeur
authors.forename: M
authors.initials: M
authors.lastname: Yazidi
authors.forename: B
authors.initials: B
authors.lastname: Ftouhi
authors.forename: H
authors.initials: H
authors.lastname: Slimane
mesh_terms: D000293:Adolescent; D000483:Alleles; D003922:Diabetes Mellitus, Type 1 / Q000175:diagnosis* / Q000235:genetics; D016883:Diabetic Ketoacidosis / Q000175:diagnosis / Q000235:genetics; D005260:Female; D005359:Fibrous Dysplasia, Polyostotic / Q000175:diagnosis* / Q000235:genetics; D059866:HLA-DQ beta-Chains / Q000235:genetics; D059811:HLA-DRB1 Chains / Q000235:genetics; D006801:Humans; D010641:Phenotype
chemical_list: C488436:HLA DRB1*04:04 antigen; D059866:HLA-DQ beta-Chains; C069051:HLA-DQB1 antigen; D059811:HLA-DRB1 Chains