title: Simultaneous determination of mono- and disubstituted polyfluoroalkyl phosphates in drinking water by liquid chromatography-electrospray tandem mass spectrometry.
abstract: A sensitive liquid chromatography-electrospray tandem mass spectrometry method was established for the simultaneous determination of five monosubstituted polyfluoroalkyl phosphates (monoPAPs) and eight disubstituted polyfluoroalkyl phosphates (diPAPs) in drinking water. Complete separation and good retention for 13 polyfluoroalkyls phosphates (PAPs) were achieved with a Waters ACUITY UPLC BEH C8 column using a mixture of methanol/water containing 0.1% NH₄OH as the mobile phases. Extraction of drinking water samples was performed on weak anion exchange (WAX) cartridges, and the recoveries of target compounds were from 65 to 110%. The limits of quantization (LOQs) for 13 analytes were in the range of 0.4-40 ng/L. This method was applied to analyze the PAPs in drinking water samples from three cities in China. Of the 13 PAPs, six PAPs including 6:2 monoPAP (13.0 ng/L), 8:2 monoPAP (3.6 ng/L), 10:1 monoPAP (4.3-70.3 ng/L), 10:2 monoPAP (1.4-5.6 ng/L), 8:2 diPAP (0.10 ng/L), and 10:1 diPAP (0.8-3.8 ng/L) were detected.
authors.affiliation: MOE Laboratory for Earth Surface Process, College of Urban and Environmental Sciences, Peking University, Beijing 100871, China.
authors.forename: Huanhuan
authors.initials: H
authors.lastname: Ding
authors.forename: Hui
authors.initials: H
authors.lastname: Peng
authors.forename: Min
authors.initials: M
authors.lastname: Yang
authors.forename: Jianying
authors.initials: J
authors.lastname: Hu
mesh_terms: D002681:China; D002852:Chromatography, Ion Exchange / Q000379:methods*; D060766:Drinking Water / Q000737:chemistry*; D005466:Fluorocarbons / Q000032:analysis* / Q000737:chemistry / Q000302:isolation & purification; D010710:Phosphates / Q000032:analysis* / Q000737:chemistry / Q000302:isolation & purification; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D052616:Solid Phase Extraction; D053719:Tandem Mass Spectrometry / Q000379:methods*; D014874:Water Pollutants, Chemical / Q000032:analysis* / Q000737:chemistry / Q000302:isolation & purification
chemical_list: D060766:Drinking Water; D005466:Fluorocarbons; D010710:Phosphates; D014874:Water Pollutants, Chemical