title: General and practical one-pot synthesis of dihydrobenzosiloles from styrenes.
abstract: A one-pot synthesis of dihydrobenzosiloles from styrenes has been developed. The reaction involves the nickel-catalyzed hydrosilylation of styrene with diphenylsilane, followed by the iridium-catalyzed dehydrogenative cyclization. This method is efficient for both electron-rich and -deficient styrenes and exhibits good functional group tolerance, as well as excellent regioselectivity. The forming dihydrobenzosiloles can be efficiently converted into valuable benzosiloles or 2-hydroxyphenethyl alcohols.
authors.affiliation: Department of Chemistry, University of Illinois at Chicago, 845 West Taylor Street, Chicago, Illinois 60607-7061, USA.
authors.forename: Alexey
authors.initials: A
authors.lastname: Kuznetsov
authors.forename: Vladimir
authors.initials: V
authors.lastname: Gevorgyan
mesh_terms: D001554:Benzene / Q000138:chemical synthesis*; D002384:Catalysis; D003500:Cyclization; D006865:Hydrogenation; D015394:Molecular Structure; D013343:Styrenes / Q000737:chemistry*
chemical_list: D013343:Styrenes; D001554:Benzene