title: Viral hepatitis in the elderly.
abstract: As life expectancy continues to rise, elderly adults represent a rapidly growing proportion of the population. The likelihood of complications of acute and chronic liver disease and overall mortality are higher in elderly populations. Several physiological changes associated with aging, greater prevalence of co-morbid conditions, and cumulative exposure to hepatotropic viruses and environmental hepatotoxins may contribute to worse outcomes of viral hepatitis in the elderly. Although pharmacotherapy for hepatitis B and C continues to evolve, the efficacy, tolerability, and side effects of these agents have not been studied extensively in elderly adults. Immunization against hepatitis A and B in naïve elderly adults is an important public health intervention that needs to be revised and broadened.
authors.affiliation: Department of Medicine, Miller School of Medicine, University of Miami, Miami Veterans Affairs Medical Center, Miami, Florida 33125, USA. acarrionmonsalve@med.miami.edu
authors.forename: Andres F
authors.initials: AF
authors.lastname: Carrion
authors.forename: Paul
authors.initials: P
authors.lastname: Martin
mesh_terms: D000208:Acute Disease; D000368:Aged; D000998:Antiviral Agents / Q000627:therapeutic use; D019694:Hepatitis B, Chronic / Q000188:drug therapy / Q000453:epidemiology; D006526:Hepatitis C / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology; D019698:Hepatitis C, Chronic / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology; D016751:Hepatitis E / Q000175:diagnosis / Q000453:epidemiology; D006525:Hepatitis, Viral, Human / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology; D006801:Humans; D016036:Seroepidemiologic Studies; D014761:Viral Hepatitis Vaccines / Q000008:administration & dosage
chemical_list: D000998:Antiviral Agents; D014761:Viral Hepatitis Vaccines