title: One-step extraction for gas chromatography with flame photometric detection of 18 organophosphorus pesticides in Chinese medicine health wines.
abstract: An easy, rapid and selective gas chromatography with flame photometric detection (GC-FPD) method was established for simultaneously determining 18 organophosphorus pesticides (OPPs) in 80 Chinese medicine (CM) health wines. This method was based on a simple one-step extraction procedure using a little solvent without any further cleanup steps. The optimized extraction solvent for the pesticides is acetone:dichloromethane (1:1, V/V) with extraction recovery of 79.0-109.1% and relative standard deviation (RSD) of 0.36-12.68%, respectively. The limits of detection (LODs) of the established GC-FPD method for all investigated pesticides ranged from 1 to 15ngmL(-1) and limits of quantification (LOQs) from 4 to 50ngmL(-1). Out of all 80 CM health wines, 18 OPPs were found in 8 samples at low concentrations of 8.2-37.9ngmL(-1). These pesticides were successfully confirmed by GC-MS. This is the first report of determining OPPs in CM health wines, providing references for monitoring the quality of CM health wine in routine analysis.
authors.affiliation: Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100193, China.
authors.forename: Qianzhen
authors.initials: Q
authors.lastname: Liu
authors.forename: Weijun
authors.initials: W
authors.lastname: Kong
authors.forename: Feng
authors.initials: F
authors.lastname: Qiu
authors.forename: Jianhe
authors.initials: J
authors.lastname: Wei
authors.forename: Shihai
authors.initials: S
authors.lastname: Yang
authors.forename: Yuguo
authors.initials: Y
authors.lastname: Zheng
authors.forename: Meihua
authors.initials: M
authors.lastname: Yang
mesh_terms: D000096:Acetone; D002138:Calibration; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods*; D057230:Limit of Detection; D059625:Liquid-Liquid Extraction; D008752:Methylene Chloride; D009943:Organophosphorus Compounds / Q000032:analysis* / Q000302:isolation & purification*; D010575:Pesticides / Q000032:analysis* / Q000302:isolation & purification*; D015203:Reproducibility of Results; D014920:Wine / Q000032:analysis*
chemical_list: D004365:Drugs, Chinese Herbal; D009943:Organophosphorus Compounds; D010575:Pesticides; D000096:Acetone; D008752:Methylene Chloride