title: Intraoral carcinosarcoma on the floor of the mouth mimicking a benign lesion.
abstract: Carcinosarcoma is a rare malignant disease with aggressive behaviour rarely producing oral manifestations. This article reports a case of an intraoral carcinosarcoma affecting a 71-year-old black male; the diagnosis was made by histopathological and immunohistochemical analyses. Computed tomography scanning showed metastatic masses in the lungs. The patient was underwent a chemotherapy protocol regimen, but died as a consequence of the disease within 10 months of diagnosis. Distinctive characteristics of this presentation were the location of the lesion (floor of the mouth) and its clinical features resembling a benign lesion. A brief review of intraoral carcinosarcoma cases in the literature is also presented.
authors.affiliation: Stomatology and Oral Pathology Department, School of Dentistry, University of Sao Paulo, São Paulo, Brazil. camilagallo@gmail.com
authors.forename: C B
authors.initials: CB
authors.lastname: Gallo
authors.forename: S E V
authors.initials: SE
authors.lastname: Cury
authors.forename: D S
authors.initials: DS
authors.lastname: Pinto
authors.forename: D A
authors.initials: DA
authors.lastname: Migliari
authors.forename: N N
authors.initials: NN
authors.lastname: Sugaya
mesh_terms: D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use; D002296:Carcinosarcoma / Q000175:diagnosis* / Q000473:pathology / Q000556:secondary; D003937:Diagnosis, Differential; D004847:Epithelial Cells / Q000473:pathology; D017809:Fatal Outcome; D017789:Granuloma, Pyogenic / Q000175:diagnosis*; D006801:Humans; D053558:Keratin-3 / Q000032:analysis; D008175:Lung Neoplasms / Q000556:secondary; D008297:Male; D008648:Mesoderm / Q000473:pathology; D009059:Mouth Diseases / Q000175:diagnosis*; D009060:Mouth Floor / Q000473:pathology*; D009062:Mouth Neoplasms / Q000175:diagnosis* / Q000473:pathology; D014057:Tomography, X-Ray Computed / Q000379:methods; D014746:Vimentin / Q000032:analysis
chemical_list: D000970:Antineoplastic Agents; D053558:Keratin-3; D014746:Vimentin