title: First human isolate of Salmonella enterica serotype Enteritidis harboring blaCTX-M-14 in South America.
abstract: We studied a clinical isolate of Salmonella enterica serotype Enteritidis showing resistance to oxyiminocephalosporins. PCR analysis confirmed the presence of bla(CTX-M-14) linked to IS903 in a 95-kb IncI1 conjugative plasmid. Such a plasmid is maintained on account of the presence of a pndAC addiction system. Multilocus sequence typing (MLST) analysis indicated that the strain belongs to ST11. This is the first report of bla(CTX-M-14) in Salmonella Enteritidis of human origin in South America.
authors.affiliation: Departamento de Bacteriología y Virología, Instituto de Higiene, Facultad de Medicina, Universidad de la República, Montevideo, Uruguay.
authors.forename: Inés
authors.initials: I
authors.lastname: Bado
authors.forename: Virginia
authors.initials: V
authors.lastname: García-Fulgueiras
authors.forename: Nicolás F
authors.initials: NF
authors.lastname: Cordeiro
authors.forename: Laura
authors.initials: L
authors.lastname: Betancor
authors.forename: Leticia
authors.initials: L
authors.lastname: Caiata
authors.forename: Verónica
authors.initials: V
authors.lastname: Seija
authors.forename: Luciana
authors.initials: L
authors.lastname: Robino
authors.forename: Gabriela
authors.initials: G
authors.lastname: Algorta
authors.forename: José A
authors.initials: JA
authors.lastname: Chabalgoity
authors.forename: Juan A
authors.initials: JA
authors.lastname: Ayala
authors.forename: Gabriel O
authors.initials: GO
authors.lastname: Gutkind
authors.forename: Rafael
authors.initials: R
authors.lastname: Vignoli
mesh_terms: D000368:Aged; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D018550:Cephalosporin Resistance / Q000235:genetics; D003227:Conjugation, Genetic; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications; D008826:Microbial Sensitivity Tests; D010957:Plasmids / Q000235:genetics; D016133:Polymerase Chain Reaction; D012480:Salmonella Infections / Q000382:microbiology*; D012477:Salmonella enteritidis / Q000187:drug effects* / Q000235:genetics*; D013020:South America; D014583:Uruguay; D001618:beta-Lactamases / Q000235:genetics*
chemical_list: D000900:Anti-Bacterial Agents; C456080:beta-lactamase CTX-M-14; D001618:beta-Lactamases