title: Coming events cast their shadows before: detecting inflammation in the acute diabetic foot and the foot in remission.
abstract: The incidence of diabetic foot complications, most notably wounds, is increasing worldwide. Most people who present for care of a foot wound will become infected. Globally, this results in one major amputation every 30 seconds with over 2500 limbs lost per day. Presently, clinicians assess circulation, neuropathy and plantar pressures to identify the risk of foot ulceration. Several studies have suggested prevention of foot ulcers by identifying individuals at high risk and treating for lower extremity complications. Our group has proposed several diagnostics as well as prevention strategies, especially thermography and thermometry for management of patients with diabetic foot complications. These strategies employ non-invasive assessment of inflammation for acute as well as chronic care for the foot, with the intent to prevent ulceration/re-ulceration and subsequent traumatic amputations. The authors' review some important clinical studies and ongoing research in this area, with the long-term goal to further the role of thermography and thermometry in clinical care for the diabetic foot.
authors.affiliation: Southern Arizona Limb Salvage Alliance (SALSA), College of Medicine, University of Arizona, Tucson, AZ 85724, USA.
authors.forename: Manish
authors.initials: M
authors.lastname: Bharara
authors.forename: Jeffrey
authors.initials: J
authors.lastname: Schoess
authors.forename: David G
authors.initials: DG
authors.lastname: Armstrong
mesh_terms: D000208:Acute Disease; D017719:Diabetic Foot / Q000150:complications* / Q000276:immunology / Q000517:prevention & control*; D006801:Humans; D007249:Inflammation / Q000175:diagnosis* / Q000276:immunology / Q000517:prevention & control*; D012074:Remission Induction; D013817:Thermography; D013821:Thermometers