title: A case of primary diffuse leptomeningeal gliomatosis predominantly involving the cervical spinal cord and mimicking chronic meningitis.
abstract: Gliomas may rarely arise in the leptomeninges without any evidence of intraaxial     involvement. A case of primary diffuse leptomeningeal gliomatosis (PDLG)     histologically diagnosed as oligoastrocytoma is presented. A 50-year-old woman     presented with nausea, vomiting and headache. Magnetic resonance imaging (MRI)     of cranium and cervical region revealed dural thickening starting from the     craniocervical junction to the level of C4 without any parenchymal lesions. CSF     examination showed an increase in protein and decrease in glucose levels. There     were neither any kind of atypical cells nor any kind of growth in bacterial     cultures. The patient underwent biopsy at the level of C1 for diagnosis. The     specimen was diagnosed as primary diffuse leptomeningeal gliomatosis, with     phenotypic features of astrocytoma and oligodendroglioma.
authors.affiliation: Department of Neurosurgery, Faculty of Medicine, Marmara University, Istanbul, Turkey.
authors.forename: Dilara Savci
authors.initials: DS
authors.lastname: Heijink
authors.forename: Kamran
authors.initials: K
authors.lastname: Urgun
authors.forename: Aydin
authors.initials: A
authors.lastname: Sav
authors.forename: Askin
authors.initials: A
authors.lastname: Seker
authors.forename: Deniz
authors.initials: D
authors.lastname: Konya
mesh_terms: D002574:Cervical Vertebrae / Q000473:pathology*; D003937:Diagnosis, Differential; D005260:Female; D006261:Headache / Q000209:etiology; D006801:Humans; D006849:Hydrocephalus / Q000175:diagnosis; D007150:Immunohistochemistry; D008279:Magnetic Resonance Imaging; D008577:Meningeal Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D008875:Middle Aged; D009325:Nausea / Q000209:etiology; D018302:Neoplasms, Neuroepithelial / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D010243:Paralysis / Q000209:etiology; D013120:Spinal Cord Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D014390:Tuberculosis, Meningeal / Q000175:diagnosis*; D014839:Vomiting / Q000209:etiology