title: Redundant pathways of sunscreen biosynthesis in a cyanobacterium.
abstract: Route of the sun block: according to empirical evidence, sun-screening mycosporine-like amino acids (MAAs) in Eukarya originate from the shikimic acid pathway, whereas in cyanobacteria, biosynthesis of the MAA shinorine reportedly occurs through the pentose phosphate pathway. However, gene deletion shows that the cyanobacterium Anabaena variabilis ATCC 29143 does not biosynthesise shinorine exclusively by this route.
authors.affiliation: Institute of Pharmaceutical Science, King's College London, 150 Stamford Street, London SE1 9NH, UK.
authors.forename: Edward
authors.initials: E
authors.lastname: Spence
authors.forename: Walter C
authors.initials: WC
authors.lastname: Dunlap
authors.forename: J Malcolm
authors.initials: JM
authors.lastname: Shick
authors.forename: Paul F
authors.initials: PF
authors.lastname: Long
mesh_terms: D046870:Anabaena variabilis / Q000378:metabolism*; D002853:Chromatography, Liquid; D003514:Cyclohexylamines; D005998:Glycine / Q000031:analogs & derivatives* / Q000096:biosynthesis; D013056:Spectrophotometry, Ultraviolet; D053719:Tandem Mass Spectrometry; D014466:Ultraviolet Rays
chemical_list: D003514:Cyclohexylamines; C494891:shinorine; D005998:Glycine