title: Histone code, human growth and cancer.
abstract: Future studies should shed new light on the complex relationship between HPTMs and human development. In particular, the molecular function of EZH2 and NSD1 in bone development should be addressed. Moreover, histone methylation and demethylation may be modulated by novel small molecule inhibitors[10, 11], which may pave the way to a therapeutic approach for those rare syndromes.
authors.forename: Francesco
authors.initials: F
authors.lastname: Crea
mesh_terms: D000015:Abnormalities, Multiple / Q000235:genetics*; D003409:Congenital Hypothyroidism / Q000235:genetics*; D019465:Craniofacial Abnormalities / Q000235:genetics*; D004268:DNA-Binding Proteins / Q000235:genetics*; D005260:Female; D018095:Germ-Line Mutation; D006228:Hand Deformities, Congenital / Q000235:genetics*; D006801:Humans; D008297:Male; D014157:Transcription Factors / Q000235:genetics*
chemical_list: D004268:DNA-Binding Proteins; D014157:Transcription Factors