title: [Autoimmune hepatitis/primary sclerosing cholangitis overlap syndrome in adults: report of three cases].
abstract: Overlap syndromes are cases of liver diseases that share clinical, serological, histological and radiological criteria of autoimmune hepatitis (AIH), primary biliary cirrhosis (PBC) or primary sclerosing cholangitis (PSC). No definitions have been fully established and therefore there is no solid evidence on the diagnosis and treatment. This article presents the cases of three adult patients with overlapping features of AIH and PSC. Orthotopic liver transplantation was considered the best therapeutic alternative due to advanced disease progression in one patient, while medical treatment was provided in the remaining two patients.
authors.affiliation: Grupo de Gastrohepatología y Trasplante Hepático, Hospital Pablo Tobón Uribe, Universidad de Antioquia, Medellín, Colombia. osmausa@yahoo.com
authors.forename: Oscar Mauricio
authors.initials: OM
authors.lastname: Santos
authors.forename: Edison
authors.initials: E
authors.lastname: Muñoz Ortiz
authors.forename: Camilo
authors.initials: C
authors.lastname: Pérez
authors.forename: Juan Carlos
authors.initials: JC
authors.lastname: Restrepo
mesh_terms: D000328:Adult; D015209:Cholangitis, Sclerosing / Q000175:diagnosis; D005260:Female; D019693:Hepatitis, Autoimmune / Q000175:diagnosis; D006801:Humans; D008297:Male; D008875:Middle Aged; D013577:Syndrome