title: Potential targets for anti-inflammatory and anti-allergic activities of marine algae: an overview.
abstract: The inflammatory and allergic diseases are among the most common diseases all over the world. The prevalence, severity, and complexity of these diseases are rapidly rising and considerably adding to the burden of healthcare costs. Although the synthetic and combinatorial chemistry have given rise to notable successes in the development of novel anti-inflammatory and anti-allergic drugs, but the extensive clinical use has led to the diverse and undesirable side effects. Meanwhile, the perceived value of natural products in the treatment of these diseases has yet to be fully explored. Thus, the extensive studies of alternative anti-inflammatory and anti-allergic drugs from natural products are essential. Notably, marine algae have been utilized in food products as well as in pharmaceutical products due to their biological activities and health benefit effects. Recently, marine algae have attracted a special interest as great sources of antiinflammatory and anti-allergic agents. This review presents an overview of potential anti-inflammatory and anti-allergic agents derived from marine algae and their promising applications in inflammation and allergy therapy.
authors.affiliation: Marine Biochemistry Laboratory, Department of Chemistry, Pukyong National University, Busan, Republic of Korea.
authors.forename: Thanh-Sang
authors.initials: TS
authors.lastname: Vo
authors.forename: Dai-Hung
authors.initials: DH
authors.lastname: Ngo
authors.forename: Se-Kwon
authors.initials: SK
authors.lastname: Kim
mesh_terms: D000818:Animals; D018926:Anti-Allergic Agents / Q000494:pharmacology*; D000893:Anti-Inflammatory Agents / Q000494:pharmacology*; D001688:Biological Products / Q000494:pharmacology; D000458:Cyanobacteria; D004791:Enzyme Inhibitors / Q000494:pharmacology; D016166:Free Radical Scavengers / Q000494:pharmacology; D006801:Humans; D006967:Hypersensitivity / Q000188:drug therapy; D007249:Inflammation / Q000188:drug therapy; D051379:Mice; D000459:Phaeophyceae; D051381:Rats; D000461:Rhodophyta
chemical_list: D018926:Anti-Allergic Agents; D000893:Anti-Inflammatory Agents; D001688:Biological Products; D004791:Enzyme Inhibitors; D016166:Free Radical Scavengers