title: [Post-marketing re-evaluation about usage and dosage of Chinese medicine based on human population pharmacokinetics].
abstract: The usage and dosage of Chinese patent medicine are determined by rigorous evaluation which include four clinical trail stages: I, II, III. But the usage and dosage of Chinese patent medicine are lacked re-evaluation after marketing. And this lead to unchanging or fixed of the usage and dosage of Chinese patent medicine instead of different quantity based on different situations in individual patients. The situation of Chinese patent medicine used in clinical application is far away from the idea of the "Treatment based on syndrome differentiation" in traditional Chinese medicine and personalized therapy. Human population pharmacokinetics provides data support to the personalized therapy in clinical application, and achieved the postmarking reevaluating of the usage and dosage of Chinese patent medicine. This paper briefly introduced the present situation, significance and the application of human population pharmacokinetics about re-evaluation of the usage and dosage of Chinese patent medicine after marketing.
authors.affiliation: Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, China. studentjiangjunjie@tom.com
authors.forename: Junjie
authors.initials: J
authors.lastname: Jiang
authors.forename: Yanming
authors.initials: Y
authors.lastname: Xie
mesh_terms: D002986:Clinical Trials as Topic; D006801:Humans; D008516:Medicine, Chinese Traditional / Q000009:adverse effects; D004366:Nonprescription Drugs / Q000008:administration & dosage* / Q000009:adverse effects; D010599:Pharmacokinetics; D057285:Precision Medicine; D011358:Product Surveillance, Postmarketing
chemical_list: D004366:Nonprescription Drugs