title: The reversal of a protective stoma is feasible before the complete healing of a colorectal anastomotic leak.
abstract: A proximal diverting stoma is recommended in "high-risk" conditions after total mesorectal excision. The aim of the study is to assess whether, after checking the anastomosis by using a water-soluble contrast enema (WCE), the closure of the ileostomy is feasible and safe,  even in the presence of a persistent radiological leak. From 2003 to 2010, 210 colorectal anastomoses were performed. Ileostomy was carried out in "high-risk" anastomosis. A radiological control was performed 2 weeks later. If a leakage was present, conservative therapy controlled  by serial WCEs was prescribed. Ileostomy closure was performed in the absence of leakage or with persistent leakage without clinical signs of pelvic infections. Seventy patients (33.3%) had a protective ileostomy. Fifty-eight of these (82.9%) had an uneventful course, whereas 12 (17.1%) had  clinical leakage. All 70 patients were submitted to WCE after 2 weeks. Nine of 58 patients (15.5%) and eight of 12 patients with clinical anastomotic leakage showed a leakage at radiology. All these patients were scheduled another WCE 2 months later. It showed that the anastomosis had been  healed in seven patients, whereas the 10 patients with leaks remained with ostomy until the third enema 1 month later. For all these patients, closure of the ileostomy was planned despite persistent radiological and subclinical leakage. A radiological study using WCE before closure of the  stoma is essential and stoma closure, in the presence of a persistent leakage, is possible in selected patients.
authors.affiliation: Department of Surgery, University of Trieste and Cattinara Hospital, Strada di Fiume, Trieste, Italy.
authors.forename: Silvia
authors.initials: S
authors.lastname: Palmisano
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Piccinni
authors.forename: Biagio
authors.initials: B
authors.lastname: Casagranda
authors.forename: Alessandro
authors.initials: A
authors.lastname: Balani
authors.forename: Nicolò
authors.initials: N
authors.lastname: de Manzini
mesh_terms: D057868:Anastomotic Leak / Q000175:diagnosis / Q000601:surgery*; D005240:Feasibility Studies; D005500:Follow-Up Studies; D006801:Humans; D007081:Ileostomy / Q000379:methods*; D011183:Postoperative Complications; D011860:Radiography, Abdominal; D012004:Rectal Neoplasms / Q000601:surgery; D012086:Reoperation / Q000379:methods*; D012189:Retrospective Studies; D016896:Treatment Outcome; D014945:Wound Healing