title: Control system design for a Continuous Positive Airway Pressure ventilator.
abstract: Continuous Positive Airway Pressure (CPAP) ventilation remains a mainstay treatment for obstructive sleep apnea syndrome (OSAS). Good pressure stability and pressure reduction during exhalation are of major importance to ensure clinical efficacy and comfort of CPAP therapy. In this study an experimental CPAP ventilator was constructed using an application-specific CPAP blower/motor assembly and a microprocessor. To minimize pressure variations caused by spontaneous breathing as well as the uncomfortable feeling of exhaling against positive pressure, we developed a composite control approach including the feed forward compensator and feedback proportional-integral-derivative (PID) compensator to regulate the pressure delivered to OSAS patients. The Ziegler and Nichols method was used to tune PID controller parameters. And then we used a gas flow analyzer (VT PLUS HF) to test pressure curves, flow curves and pressure-volume loops for the proposed CPAP ventilator. The results showed that it met technical criteria for sleep apnea breathing therapy equipment. Finally, the study made a quantitative comparison of pressure stability between the experimental CPAP ventilator and commercially available CPAP devices.
authors.affiliation: Department of Precise Medical Device, Shanghai Medical Instrumentation College, Shanghai, China. chenzl@smic.edu.cn
authors.forename: Zheng-Long
authors.initials: ZL
authors.lastname: Chen
authors.forename: Zhao-Yan
authors.initials: ZY
authors.lastname: Hu
authors.forename: Hou-De
authors.initials: HD
authors.lastname: Dai
mesh_terms: D000328:Adult; D000465:Algorithms; D045422:Continuous Positive Airway Pressure / Q000295:instrumentation*; D045853:Exhalation / Q000502:physiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D017286:Polysomnography; D020181:Sleep Apnea, Obstructive / Q000628:therapy*