title: Body fat distribution in women with familial partial lipodystrophy caused by mutation in the lamin A/C gene.
abstract: Familial partial lipodystrophy (FPLD), Dunnigan variety, is an autosomal dominant disorder caused due to missense mutations in the lamin A/C (LMNA) gene encoding nuclear lamina proteins. Patients with FPLD are predisposed to metabolic complications of insulin resistance such as diabetes. We sought to evaluate and compare body fat distribution with dual-emission X-ray absorptiometry in women with and without FPLD and identify densitometric, clinical and metabolic features.
authors.affiliation: Department of Medicine, Divisions of Endocrinology and Metabolism, Ribeirão Preto Medical School, São Paulo University, Brazil.
authors.forename: Luciana Z
authors.initials: LZ
authors.lastname: Monteiro
authors.forename: Maria C
authors.initials: MC
authors.lastname: Foss-Freitas
authors.forename: Renan M
authors.initials: RM
authors.lastname: Júnior Montenegro
authors.forename: Milton C
authors.initials: MC
authors.lastname: Foss