title: Significance of surgical treatment of liver metastases from gastric cancer.
abstract: OBJECTIVE
  The optimal treatment of liver metastases from gastric cancer (LMGC) remains uncertain. We retrospectively compared surgical treatment with chemotherapy alone and identified prognostic determinants.
  
  
  METHODS
  We reviewed the records of 50 consecutive patients with LMGC: 25 patients with gastrectomy plus hepatic resection (group A), 13 patients with palliative gastrectomy (group B), and 12 patients with chemotherapy alone (group C). We compared the overall survival among these three groups, and assessed prognostic factors.
  
  
  RESULTS
  Median survival time in groups A, B, and C was 33.4, 10.5, and 8.7 months, respectively. Univariate analysis found T stage, number of liver metastases, and treatment group to be significant prognostic factors. In the multivariate analysis, T stage was shown to be an independent prognostic determinant, while gastrectomy plus hepatic resection was of marginal significance compared with chemotherapy alone.
  
  
  CONCLUSIONS
  T Stage was a significant prognostic determinant, and gastrectomy plus hepatic resection could be a promising treatment for patients with LMGC.
authors.affiliation: Department of Surgery, Osaka National Hospital. 2-1-14, Hoenzaka, Chuo-ku, Osaka 540-0006, Japan.
authors.forename: Yuichiro
authors.initials: Y
authors.lastname: Miki
authors.forename: Kazumasa
authors.initials: K
authors.lastname: Fujitani
authors.forename: Motohiro
authors.initials: M
authors.lastname: Hirao
authors.forename: Yukinori
authors.initials: Y
authors.lastname: Kurokawa
authors.forename: Masayuki
authors.initials: M
authors.lastname: Mano
authors.forename: Masanori
authors.initials: M
authors.lastname: Tsujie
authors.forename: Atsushi
authors.initials: A
authors.lastname: Miyamoto
authors.forename: Shoji
authors.initials: S
authors.lastname: Nakamori
authors.forename: Toshimasa
authors.initials: T
authors.lastname: Tsujinaka
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000188:drug therapy / Q000556:secondary* / Q000601:surgery*; D008197:Lymph Node Excision; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011379:Prognosis; D012189:Retrospective Studies; D013274:Stomach Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery*; D015996:Survival Rate