title: (Mis)treating the pharmacogenetic incidentalome.
abstract: Genome-wide screening is anticipated to accelerate the development of personalized medicine by identifying and exploiting new associations between genomic variants and drug responses. However, this goal could be undermined if care is not taken to minimize the impact of pharmacogenomic associations that turn out to have narrower implications than suggested by initial studies.
authors.affiliation: Harvard Medical School Center for Biomedical Informatics, 10 Shattuck Street, Boston, Massachusetts 02115, USA. isaac_kohane@harvard.edu
authors.forename: Isaac S
authors.initials: IS
authors.lastname: Kohane
mesh_terms: D064420:Drug-Related Side Effects and Adverse Reactions; D020022:Genetic Predisposition to Disease / Q000235:genetics; D006801:Humans; D033162:Incidental Findings; D004364:Pharmaceutical Preparations / Q000008:administration & dosage / Q000378:metabolism; D010597:Pharmacogenetics; D011110:Polymorphism, Genetic / Q000235:genetics; D057285:Precision Medicine / Q000009:adverse effects / Q000379:methods
chemical_list: D004364:Pharmaceutical Preparations