title: Noninvasive evaluation of 3D hemodynamics in a complex case of single ventricle physiology.
abstract: We report the comprehensive evaluation of the complex hemodynamics in a rare case of a pediatric patient after repair of congenital heart disease with multiple abnormalities including hypoplastic left heart, double outlet right ventricle, transposition of great arteries, ventricular septal defect, aortic coarctation, and total cavopulmonary connection. Based on a single measurement, whole-heart flow-sensitive 4D magnetic resonance imaging (MRI) was able to demonstrate a number of regional flow alterations such as poststenotic helix formation and asymmetric flow distributions for the double arterial outlet and to the left and right lungs. Our findings illustrate the potential role of flow-sensitive 4D MRI as a noninvasive and radiation-free technique for the frequent postinterventional follow-up in these pediatric patients.
authors.affiliation: Department of Radiology, Medical Physics, University Medical Center, Freiburg, Germany. mmarkl@northwestern.edu
authors.forename: Michael
authors.initials: M
authors.lastname: Markl
authors.forename: Julia
authors.initials: J
authors.lastname: Geiger
authors.forename: Bernd
authors.initials: B
authors.lastname: Jung
authors.forename: Daniel
authors.initials: D
authors.lastname: Hirtler
authors.forename: Raoul
authors.initials: R
authors.lastname: Arnold
mesh_terms: D001783:Blood Flow Velocity; D002675:Child, Preschool; D003326:Coronary Circulation; D006352:Heart Ventricles / Q000002:abnormalities* / Q000503:physiopathology* / Q000601:surgery; D006801:Humans; D021621:Imaging, Three-Dimensional / Q000379:methods*; D019028:Magnetic Resonance Imaging, Cine / Q000379:methods*; D008297:Male; D011379:Prognosis; D013318:Stroke Volume; D016896:Treatment Outcome