title: Angiosarcoma of skull in a pregnant woman: case report and review of the literature.
abstract: Angiosarcoma is a rare tumor of bone that uncommonly involves the skull. Primary     neoplasms of the skull represent 2.6% of primary neoplasms of bone. We wish to     report a case of angiosarcoma of he skull in an 18-year-old pregnant woman who     presented with a rapidly growing left frontotemporal mass. Neuroimaging revealed     a left frontotemporal mass with destruction of diploic space and both tables and     with extension to the subgaleal and epidural spaces. The patient underwent     surgery and the tumor was removed totally. Histological features of angiosarcoma     were seen in the pathology study. She received adjuvant chemotherapy and     radiation therapy. She has remained well during 6 years of follow-up with no     evidence of recurrence. Angiosarcoma is a rare malignant bone tumor of vascular     origin. Our case is the only female patient with skull angiosarcoma that has     been reported so far.
authors.affiliation: Loghman-e-Hakim Medical Center, Shahid Beheshti University of Medical Sciences, Department of Neurosurgery, Tehran, Islamic Republic of Iran. mdsamadian@hotmail.com
authors.forename: Mohammad
authors.initials: M
authors.lastname: Samadian
authors.forename: Mohammad
authors.initials: M
authors.lastname: Rakhshan
authors.forename: Karim
authors.initials: K
authors.lastname: Haddadian
authors.forename: Omidvar
authors.initials: O
authors.lastname: Rezaei
authors.forename: Seyed Ali Modaress
authors.initials: SA
authors.lastname: Zamani
authors.forename: Fatemeh
authors.initials: F
authors.lastname: Khormaee
mesh_terms: D000293:Adolescent; D005260:Female; D006394:Hemangiosarcoma / Q000473:pathology* / Q000601:surgery*; D006801:Humans; D007150:Immunohistochemistry; D008279:Magnetic Resonance Imaging; D019635:Neurosurgical Procedures / Q000379:methods*; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000473:pathology* / Q000601:surgery; D012888:Skull Neoplasms / Q000473:pathology* / Q000601:surgery*; D014057:Tomography, X-Ray Computed