title: Use of platelet-rich fibrin membrane following treatment of gingival recession: a randomized clinical trial.
abstract: This 6-month randomized controlled clinical study primarily aimed to compare the results achieved by the use of a platelet-rich fibrin (PRF) membrane or connective tissue graft (CTG) in the treatment of gingival recession and to evaluate the clinical impact of PRF on early wound healing and subjective patient discomfort. Use of a PRF membrane in gingival recession treatment provided acceptable clinical results, followed by enhanced wound healing and decreased subjective patient discomfort compared to CTG-treated gingival recessions. No difference could be found between PRF and CTG procedures in gingival recession therapy, except for a greater gain in keratinized tissue width obtained in the CTG group and enhanced wound healing associated with the PRF group.
authors.affiliation: Department of Periodontics, School of Dentistry, University of Belgrade, Begrade, Republic of Serbia. drsashaj@gmail.com
authors.forename: Sasha
authors.initials: S
authors.lastname: Jankovic
authors.forename: Zoran
authors.initials: Z
authors.lastname: Aleksic
authors.forename: Perry
authors.initials: P
authors.lastname: Klokkevold
authors.forename: Vojislav
authors.initials: V
authors.lastname: Lekovic
authors.forename: Bozidar
authors.initials: B
authors.lastname: Dimitrijevic
authors.forename: E Barrie
authors.initials: EB
authors.lastname: Kenney
authors.forename: Paulo
authors.initials: P
authors.lastname: Camargo
mesh_terms: D000328:Adult; D001792:Blood Platelets / Q000502:physiology*; D003238:Connective Tissue / Q000637:transplantation; D004848:Epithelium / Q000502:physiology; D005260:Female; D005337:Fibrin / Q000627:therapeutic use*; D005500:Follow-Up Studies; D005881:Gingiva / Q000473:pathology / Q000637:transplantation; D005884:Gingival Hemorrhage / Q000209:etiology; D005889:Gingival Recession / Q000473:pathology / Q000601:surgery*; D006097:Granulation Tissue / Q000473:pathology; D006801:Humans; D008297:Male; D008567:Membranes, Artificial; D008875:Middle Aged; D010147:Pain Measurement; D010149:Postoperative Pain / Q000209:etiology; D017622:Periodontal Attachment Loss / Q000601:surgery; D010514:Periodontal Pocket / Q000601:surgery; D010865:Pilot Projects; D011183:Postoperative Complications; D013524:Surgical Flaps; D014945:Wound Healing / Q000502:physiology; D055815:Young Adult
chemical_list: D008567:Membranes, Artificial; D005337:Fibrin