title: Measurement of central systolic blood pressure by pulse volume plethysmography with a noninvasive blood pressure monitor.
abstract: BACKGROUND
  Central systolic blood pressure (SBP) can be estimated by an oscillometric method developed from a pulse volume plethysmography (PVP) device. The present study applied this novel method to a noninvasive blood pressure monitor (NBPM).
  
  
  METHODS
  We enrolled 50 patients (37 men, age range 30-84 years) referred for cardiac catheterization. Invasive right brachial and central aortic pressures (using a dual-sensor pressure catheter), and noninvasive left brachial SBP and diastolic blood pressure (DBP), and PVP waveform (using a customized NBPM) were simultaneously recorded. Central SBP was estimated by analysis of the PVP waveform calibrated to the noninvasive SBP and DBP, using both the original (CSBP-O) and the newly generated (CSBP-N) regression equations. The reproducibility of the invasive central SBP by CSBP-O and CSBP-N was examined using the concordance correlation coefficient.
  
  
  RESULTS
  Overall, the invasive central aortic SBP ranged 86-176 with a mean of 124 ± 21 mm Hg. The mean differences between the estimated and the invasive central SBP were -1.3 ± 6.7 mm Hg for CSBP-O and 0.0 ± 6.2 mm Hg for CSBP-N, respectively. The concordance correlation coefficients for CSBP-O and CSBP-N were 0.94 (95% confidence interval (CI): 0.93-0.94) and 0.95 (95% CI: 0.95-0.96), and both were significantly better than that for the noninvasive brachial SBP (0.87, 0.84-0.91) indicated by non-overlapping CIs.
  
  
  CONCLUSIONS
  The PVP method for noninvasive estimation of central SBP can be applied to a commonly used NBPM. Whether the NBPM-derived central SBP is superior to the noninvasive brachial SBP in the prediction of cardiovascular risks remains to be investigated.
authors.affiliation: Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.
authors.forename: Shih-Hsien
authors.initials: SH
authors.lastname: Sung
authors.forename: Hao-Min
authors.initials: HM
authors.lastname: Cheng
authors.forename: Shao-Yuan
authors.initials: SY
authors.lastname: Chuang
authors.forename: Yuan-Ta
authors.initials: YT
authors.lastname: Shih
authors.forename: Kang-Ling
authors.initials: KL
authors.lastname: Wang
authors.forename: Ying-Hwa
authors.initials: YH
authors.lastname: Chen
authors.forename: Shing-Jong
authors.initials: SJ
authors.lastname: Lin
authors.forename: Wen-Chung
authors.initials: WC
authors.lastname: Yu
authors.forename: Chen-Huan
authors.initials: CH
authors.lastname: Chen
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001794:Blood Pressure / Q000502:physiology*; D001795:Blood Pressure Determination / Q000295:instrumentation / Q000379:methods; D015924:Blood Pressure Monitors; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D009991:Oscillometry / Q000295:instrumentation / Q000379:methods; D010991:Plethysmography / Q000295:instrumentation* / Q000379:methods*; D011674:Pulse; D013599:Systole / Q000502:physiology