title: N-Naphthyl peptoid foldamers exhibiting atropisomerism.
abstract: We introduce peptoid oligomers incorporating N-(1)-naphthyl glycine monomers. Axial chirality was established due to restricted rotation about the C-N(aryl) bond. Atropisomerism of both linear and cyclic peptoids was investigated by computational analysis, dynamic HPLC, and X-ray crystallographic studies.
authors.affiliation: Department of Chemistry and Center for Genomics and Systems Biology, New York University, New York, New York 10003, USA.
authors.forename: Bishwajit
authors.initials: B
authors.lastname: Paul
authors.forename: Glenn L
authors.initials: GL
authors.lastname: Butterfoss
authors.forename: Mikki G
authors.initials: MG
authors.lastname: Boswell
authors.forename: Mia L
authors.initials: ML
authors.lastname: Huang
authors.forename: Richard
authors.initials: R
authors.lastname: Bonneau
authors.forename: Christian
authors.initials: C
authors.lastname: Wolf
authors.forename: Kent
authors.initials: K
authors.lastname: Kirshenbaum
mesh_terms: D008958:Models, Molecular; D034444:Peptoids / Q000737:chemistry*; D017510:Protein Folding; D013237:Stereoisomerism
chemical_list: D034444:Peptoids