title: Management and prevention of prosthetic joint infection.
abstract: Prosthetic joint infection (PJI) is a serious complication of total joint arthroplasty (TJA) that can negatively affect functional status and quality of life. This article examines the epidemiology of PJI and reviews current diagnostic, treatment, and management strategies. Diagnosis can be challenging because presenting symptoms are often nonspecific and there is no simple gold standard diagnostic test. Successful treatment of PJI requires a combination of medical and surgical strategies. Given the devastating nature of PJI and the increasing numbers of TJAs performed, prevention efforts remain critical.
authors.affiliation: Division of Infectious Diseases and Geriatric Medicine, University of Michigan, Ann Arbor, MI 48105, USA.
authors.forename: Emily K
authors.initials: EK
authors.lastname: Shuman
authors.forename: Andrew
authors.initials: A
authors.lastname: Urquhart
authors.forename: Preeti N
authors.initials: PN
authors.lastname: Malani
mesh_terms: D000890:Anti-Infective Agents / Q000627:therapeutic use; D001424:Bacterial Infections / Q000175:diagnosis / Q000517:prevention & control / Q000628:therapy*; D020878:Device Removal; D019468:Disease Management; D004866:Equipment Contamination / Q000517:prevention & control; D006801:Humans; D007595:Joint Prosthesis; D016459:Prosthesis-Related Infections / Q000175:diagnosis / Q000517:prevention & control / Q000628:therapy*; D012307:Risk Factors
chemical_list: D000890:Anti-Infective Agents