title: Unique manifestations of catecholamine release in malignant pheochromocytoma: an experience within an inpatient palliative care unit.
abstract: Malignant pheochromocytoma is a rare disorder. We describe the case of a 41-year-old female with disseminated metastatic pheochromocytoma who was admitted for ongoing palliative and supportive care within an inpatient palliative care unit. Predominant symptoms included severe gastrointestinal pseudo-obstruction and orthostatic hypotension Pseudo-obstruction management included percutaneous enterogastric and percutaneous enterojejunostomy tubes for gastric decompression and delivery of nutrition, respectively. Debilitating symptoms of orthostatic hypotension were mitigated with judicious fluid balance and appropriate use of adrenergic blocking agents. The potential for metoclopramide to worsen symptoms also was a significant component of management. The case presents rare features of this unusual disease and is unique for its setting within the confines of a palliative care unit.
authors.affiliation: Calvary Hospital, Kogarah, New South Wales, Australia. ncoupe@gmp.usyd.edu.au
authors.forename: Nicholas Anthony
authors.initials: NA
authors.lastname: Coupe
authors.forename: Judith
authors.initials: J
authors.lastname: Lacey
authors.forename: Christine
authors.initials: C
authors.lastname: Sanderson
mesh_terms: D000310:Adrenal Gland Neoplasms / Q000378:metabolism* / Q000628:therapy; D000328:Adult; D002395:Catecholamines / Q000378:metabolism*; D005260:Female; D006801:Humans; D010166:Palliative Care; D010673:Pheochromocytoma / Q000378:metabolism* / Q000628:therapy
chemical_list: D002395:Catecholamines