title: Cell polarity: tension quenches the rear.
abstract: A combination of biophysical perturbations and computer simulations shows that leading edge protrusion in crawling cells increases membrane tension, which constrains the protruding front to one side of the cell, thereby maintaining its polarity.
authors.affiliation: Department of Neurobiology, Physiology and Behavior and Department of Mathematics, University of California, Davis, CA 95616, USA. mogilner@math.ucdavis.edu
authors.forename: Alex
authors.initials: A
authors.lastname: Mogilner
authors.forename: Jie
authors.initials: J
authors.lastname: Zhu
mesh_terms: D002465:Cell Movement; D016764:Cell Polarity; D009504:Neutrophils / Q000502:physiology*