title: Long term respiratory outcomes of congenital diaphragmatic hernia, esophageal atresia, and cardiovascular anomalies.
abstract: Intrathoracic congenital malformations may be associated with long-term pulmonary morbidity. This certainly is the case for congenital diaphragmatic hernia, esophageal atresia and cardiac and aortic arch abnormalities. These conditions have variable degrees of impaired development of both the airways and lung vasculature, with a postnatal impact on lung function and bronchial reactivity. Pulmonary complications are themselves frequently associated to non-pulmonary morbidities, including gastrointestinal and orthopaedic complications. These are best recognized in a structured multidisciplinary follow-up clinic so that they can be actively managed.
authors.affiliation: Pediatric Pulmonology, APHP, Necker-Enfants Malades, Paris, France.
authors.forename: Christophe
authors.initials: C
authors.lastname: Delacourt
authors.forename: Alice
authors.initials: A
authors.lastname: Hadchouel
authors.forename: Jaan
authors.initials: J
authors.lastname: Toelen
authors.forename: Maissa
authors.initials: M
authors.lastname: Rayyan
authors.forename: Jacques
authors.initials: J
authors.lastname: de Blic
authors.forename: Jan
authors.initials: J
authors.lastname: Deprest
mesh_terms: D002658:Developmental Disabilities / Q000209:etiology* / Q000517:prevention & control; D004933:Esophageal Atresia / Q000150:complications* / Q000517:prevention & control; D005183:Failure to Thrive; D006330:Heart Defects, Congenital / Q000150:complications* / Q000517:prevention & control; D006548:Hernia, Diaphragmatic / Q000150:complications / Q000517:prevention & control; D065630:Hernias, Diaphragmatic, Congenital; D006801:Humans; D007223:Infant; D008168:Lung / Q000002:abnormalities* / Q000098:blood supply; D008171:Lung Diseases / Q000209:etiology* / Q000517:prevention & control; D012307:Risk Factors