title: A new 14-membered tetraazamacrocycle-bonded silica stationary phase for reversed-phase high-performance liquid chromatography.
abstract: A new high-performance liquid chromatography stationary phase has been prepared by covalently bonding 14-membered tetraazamacrocycle to silica gel using γ-chloropropyltrimethoxylsilane as coupling agent. The structure of the new material was characterized by infrared spectroscopy and elemental analysis. With 32 solutes including aromatic and aliphatic compounds, the linear solvation energy relationship method was successfully used to chromatographically evaluate the new phase in reversed phase mode. The retention property of the new phase shows evident similarity with that of ODS stationary phase, as well as distinctive, unique retention characteristics. The separations of n-alkylbenzene, carbamate and organophosphorus pesticides with diversified functional groups as well as phenolic compounds demonstrate that in addition to hydrophobic interaction, dipole-dipole interaction and hydrogen bonding interaction plus acid-base equilibrium could also be simultaneously offered by this new stationary phase, as a result excellent chromatographic performances are guaranteed.
authors.affiliation: School of Chemistry and Chemical Engineering, Henan University of Technology, Zhengzhou 450001, China. lijunhe@haut.edu.cn
authors.forename: Lijun
authors.initials: L
authors.lastname: He
authors.forename: Mingliang
authors.initials: M
authors.lastname: Zhang
authors.forename: Wenjie
authors.initials: W
authors.lastname: Zhao
authors.forename: Jie
authors.initials: J
authors.lastname: Liu
authors.forename: Xiuming
authors.initials: X
authors.lastname: Jiang
authors.forename: Shusheng
authors.initials: S
authors.lastname: Zhang
authors.forename: Lingbo
authors.initials: L
authors.lastname: Qu
mesh_terms: D001372:Aza Compounds / Q000737:chemistry*; D002219:Carbamates / Q000032:analysis; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D056148:Chromatography, Reverse-Phase / Q000379:methods*; D006860:Hydrogen Bonding; D057927:Hydrophobic and Hydrophilic Interactions; D009943:Organophosphorus Compounds / Q000032:analysis; D010575:Pesticides / Q000032:analysis; D012821:Silanes / Q000737:chemistry; D058428:Silica Gel / Q000737:chemistry*; D013055:Spectrophotometry, Infrared; D055672:Static Electricity
chemical_list: D001372:Aza Compounds; D002219:Carbamates; D009943:Organophosphorus Compounds; D010575:Pesticides; D012821:Silanes; D058428:Silica Gel