title: [Long-term results of chronic occlusion recanalization in patients with coronary heart disease].
abstract: The study was undertaken to assess the long-term results of recanalization of chronically occluded coronary arteries, by applying drug-eluting stents to patients with coronary heart disease. The study enrolled 585 patients with one-vessel occlusive lesion of one of three great coronary arteries (TIMI 0; occlusion duration, > or = 3 months): 321 patients who underwent successful recanalization of chronic occlusion and further implantation of drug-eluting stents and 264 patients who received drug therapy (a control group). The short- and long-term results of recanalization were investigated. The follow-up averaged 1095 +/- 36 days; reexaminations were made after 1, 2, and 3 years. The direct success rate of recanalization of chronically occluded coronary arteries was 84.9% (321/378). The results of a 3-year follow-up showed the efficiency and expediency of endovascular recanalization of chronic occlusions: the invasively treated patients had the symptoms of angina pectoris and heart failure significantly less frequently, showed higher exercise tolerance and a less need for antianginal therapy, and had a better long-term prognosis.
authors.forename: M A
authors.initials: MA
authors.lastname: Maslennikov
authors.forename: B A
authors.initials: BA
authors.lastname: Rudenko
authors.forename: A P
authors.initials: AP
authors.lastname: Savchenko
authors.forename: Iu A
authors.initials: IuA
authors.lastname: Karpov
mesh_terms: D000368:Aged; D015906:Angioplasty, Balloon, Coronary / Q000009:adverse effects / Q000379:methods; D002317:Cardiovascular Agents / Q000627:therapeutic use; D002908:Chronic Disease; D003131:Combined Modality Therapy; D017023:Coronary Angiography / Q000379:methods*; D054059:Coronary Occlusion / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy*; D023903:Coronary Restenosis / Q000175:diagnosis* / Q000209:etiology; D003331:Coronary Vessels / Q000473:pathology / Q000503:physiopathology; D054855:Drug-Eluting Stents; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D010043:Outcome and Process Assessment, Health Care / Q000706:statistics & numerical data; D013995:Time; D016896:Treatment Outcome
chemical_list: D002317:Cardiovascular Agents