title: Breast cancer hypothesis 1978: Shift of the conceptual framework.
abstract: One hundred medical hypotheses from the 1970s were reviewed, in a book in London, UK, in order to reassess the predictive values and practical realizations of hypotheses suggested more than 30 years ago. The hypothesis-testing study of breast cancer of 1978, corroborating evidence of a significant association between barrier contraception (condom use) and breast cancer in American married women was also included (No. 44). As a reply, presented is the evolving line of the hypothesis into evidence of the potential of primary prevention of the disease, and a Table of the envisioned shift of the conceptual framework (paradigm) of breast cancer.
authors.affiliation: Retired Lecturer, Faculty of Medicine, Kuwait University.
authors.forename: A N
authors.initials: AN
authors.lastname: Gjorgov
mesh_terms: D001943:Breast Neoplasms / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control; D017280:Condoms / Q000009:adverse effects / Q000706:statistics & numerical data; D042121:Contraception, Barrier / Q000009:adverse effects / Q000706:statistics & numerical data; D005260:Female; D014943:Global Health / Q000639:trends; D006801:Humans; D011315:Preventive Medicine; D011322:Primary Prevention / Q000379:methods / Q000639:trends*; D016387:Women's Health / Q000639:trends