title: Evaluating hemodynamic outcomes of different dosages of intravenous nitroglycerin after coronary artery bypass graft surgery.
abstract: BACKGROUND
  Hemodynamic deterioration is a common postoperative problem. Intravenous nitroglycerin (NTG) is used for prevention of this complication. Nitroglycerin has different doses and is primarily a vasodilator. Applying different doses of intravenous NTG can induce different effects on post-operative cardiac instability, so we aimed to investigate whether there was a difference need for administration of inotrope drugs in patients undergoing CABG as indicators of cardiac instability.
  
  
  METHODS
  Sixty seven consecutive patients enrolled in this double-blind clinical trial performed in Shahid Rajaee hospital, Shahid Beheshti University of Medical Science, Tehran, Iran.
  
  
  RESULTS
  The decrease in blood pressure and the need for administration of epinephrine was more prevalent in warming up period in all three groups. No need for administration of epinephrine was detected before and during anesthesia in groups receiving 100 and 150 μg/min intravenous nitroglycerin, but 6.6 percent (1 patient) of patients receiving 50 μg/min epinephrine, demonstrated a decrease in blood pressure which necessitated the use of epinephrine.
  
  
  CONCLUSIONS
  It seemed that application of different doses of intravenous nitroglycerin did not exert a significant influence on cardiac instability and the need for use of inotrope drugs.
authors.affiliation: Assistant Professor, Department of Cardiac Anesthesiology, Shahid Rajaee Hospital, Isfahan University of Medical Science, Isfahan, Iran.
authors.forename: Gholamreza
authors.initials: G
authors.lastname: Masoumi
authors.forename: Evaz
authors.initials: E
authors.lastname: Hidarpour
authors.forename: Ali Sadeghpour
authors.initials: AS
authors.lastname: Tabae
authors.forename: Mohsen
authors.initials: M
authors.lastname: Ziayeefard
authors.forename: Atosa
authors.initials: A
authors.lastname: Azarasa
authors.forename: Amin
authors.initials: A
authors.lastname: Abneshahidi
authors.forename: Sanam Javid
authors.initials: SJ
authors.lastname: Anbardan
authors.forename: Parviz
authors.initials: P
authors.lastname: Kashefi