title: Motion-insensitive optical coherence tomography based micro-angiography.
abstract: An improved image processing procedure for suppressing the phase noise due to a motion artifact acquired during optical coherence tomography scanning and effectively illustrating the blood vessel distribution in a living tissue is demonstrated. This new processing procedure and the widely used procedure for micro-angiography application are based on the selection of high-frequency components in the spatial-frequency spectrum of B-mode scanning (x-space), which are contributed from the image portions of moving objects. However, by switching the processing order between the x-space and k-space, the new processing procedure shows the superior function of effectively suppressing the phase noise due to a motion artifact. After the blood vessel positions are precisely acquired based on the new processing procedure, the projected blood flow speed can be more accurately calibrated based on a previously reported method. The demonstrated new procedure is useful for clinical micro-angiography application, in which a stepping motor of generating motion artifacts is usually used in the scanning probe.
authors.affiliation: Institute of Photonics and Optoelectronics, National Taiwan University, Taipei, Taiwan.
authors.forename: Ting-Ta
authors.initials: TT
authors.lastname: Chi
authors.forename: Cheng-Kuang
authors.initials: CK
authors.lastname: Lee
authors.forename: Chiung-Ting
authors.initials: CT
authors.lastname: Wu
authors.forename: Chih-Chung
authors.initials: CC
authors.lastname: Yang
authors.forename: Meng-Tsan
authors.initials: MT
authors.lastname: Tsai
authors.forename: Chun-Ping
authors.initials: CP
authors.lastname: Chiang
mesh_terms: D000792:Angiography / Q000295:instrumentation*; D016477:Artifacts; D004867:Equipment Design; D019544:Equipment Failure Analysis; D007089:Image Enhancement / Q000295:instrumentation*; D008904:Miniaturization; D009038:Motion; D041623:Tomography, Optical Coherence / Q000295:instrumentation*