title: Vasa previa and postpartum hysterectomy in maternal Rh alloimmunization.
abstract: Velamentous insertion of the cord, or vasa previa, is a malady where fetal vessels tranverse membranes ahead of the fetal part. The incidence of vasa previa is 1: 2000-3000 deliveries. Fetal mortality is over 50-75%. Early diagnosis is needed because these deliveries require emergency cesarean section; it is especially more common with placenta percreta, uterine atony and hemorrhage. Intravascular infusion of red blood cells (RBCs) into the fetus is one of the most successful means of in utero therapy for severe fetal anemia caused by RBC alloimmunization. We performed four fetal intrauterine intravascular transfusions (IVT) as therapy for severe fetal anemia. The patient underwent elective cesarean section. After delivery, profound uterine atony and vaginal hemorrhage were noted and the patient underwent hysterectomy. Pathological examination of the placenta and umbilical cord documented velamentous insertion of the cord. Before intrauterine IVT a detailed US examination is necessary to exclude vasa previa or placenta previa. Uterine atony may be result after a diagnosis of placenta previa or vasa previa. Intrauterine IVT is an irreplaceable diagnostic procedure in the treatment of severe fetal anemia.
authors.affiliation: Institute for Gynecology and Obstetrics, Clinical Center of Serbia, Belgrade. ivana.r.babovic@gmail.com
authors.forename: I
authors.initials: I
authors.lastname: Babovic
authors.forename: D
authors.initials: D
authors.lastname: Plecas
authors.forename: S
authors.initials: S
authors.lastname: Plesinac
authors.forename: O
authors.initials: O
authors.lastname: Antonovic
mesh_terms: D000328:Adult; D001805:Blood Transfusion, Intrauterine; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007044:Hysterectomy; D007231:Infant, Newborn; D008297:Male; D007744:Obstetric Labor Complications / Q000628:therapy; D010922:Placenta Diseases / Q000175:diagnosis* / Q000628:therapy; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000175:diagnosis* / Q000628:therapy; D011250:Pregnancy Complications, Hematologic / Q000175:diagnosis* / Q000628:therapy; D011262:Pregnancy Trimester, Second; D011296:Prenatal Diagnosis; D014592:Uterine Hemorrhage / Q000628:therapy; D014593:Uterine Inertia / Q000628:therapy