title: Sm3+-doped germanate glass channel waveguide as light source for minimally invasive photodynamic therapy surgery.
abstract: In Sm(3+)-doped K(+)-Na(+) ion-exchanged aluminum germanate (NMAG) glass channel waveguide, a clear and compact red amplified spontaneous emission (ASE) trace is observed under the excitation of a 488nm Ar(+) laser. 78% photons of ASE fluorescence in visible region are demonstrated to be located in 600-730nm wavelength range. High-directivity and high-brightness ASE fluorescence of Sm(3+)-doped NMAG glass channel waveguide, which matches the excitation band of most photosensitizers (PS) currently used in photodynamic therapy (PDT) or clinical trials, has promising potential application as an excitation light source for PDT treatment.
authors.affiliation: School of Textile and Material Engineering, Dalian Polytechnic University, Dalian, China.
authors.forename: B J
authors.initials: BJ
authors.lastname: Chen
authors.forename: L F
authors.initials: LF
authors.lastname: Shen
authors.forename: E Y B
authors.initials: EY
authors.lastname: Pun
authors.forename: H
authors.initials: H
authors.lastname: Lin
mesh_terms: D004867:Equipment Design; D005857:Germanium / Q000737:chemistry*; D005898:Glass / Q000737:chemistry; D006801:Humans; D054020:Lasers, Gas; D054023:Lasers, Semiconductor; D019060:Minimally Invasive Surgical Procedures / Q000295:instrumentation*; D008962:Models, Theoretical; D009369:Neoplasms / Q000601:surgery*; D010778:Photochemotherapy / Q000295:instrumentation*; D017319:Photosensitizing Agents / Q000627:therapeutic use; D012493:Samarium / Q000737:chemistry*; D014467:Ultraviolet Therapy / Q000295:instrumentation
chemical_list: D017319:Photosensitizing Agents; D005857:Germanium; D012493:Samarium