title: Case for diagnosis. Acrokeratoelastoidosis.
abstract: Acrokeratoelastoidosis is a type of palmoplantar keratoderma first described by Oswaldo Gonçalves Costa, a Brazilian Dermatologist from the state of Minas Gerais. It is a rare autosomal-dominant genodermatosis; however it may occur sporadically. The disease is not congenital; rather, its onset occurs in childhood or adolescence. Clinically, the condition is characterized by multiple yellowish papules, sometimes glossy and keratotic, measuring approximately 2-4 mm in diameter, sometimes umbilicated, and located symmetrically on the sides of the hands and feet, symmetry being the most typical sign. The most common histopathological findings are hyperkeratosis, mild acanthosis and elastorrhexis, as revealed by orcein staining.
authors.affiliation: Prof. Rubem David Azulay Institute of Dermatology, Santa Casa de Misericórdia do Rio de Janeiro, Brazil. maricosta133@gmail.com
authors.forename: Mariana Carvalho
authors.initials: MC
authors.lastname: Costa
authors.forename: Eduardo
authors.initials: E
authors.lastname: Bornhausen Demarch
authors.forename: Amanda
authors.initials: A
authors.lastname: Hertz
authors.forename: Francisco Burnier Carlos
authors.initials: FB
authors.lastname: Pereira
authors.forename: David Rubem
authors.initials: DR
authors.lastname: Azulay
mesh_terms: D000052:Acanthosis Nigricans / Q000473:pathology*; D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D005533:Foot Dermatoses / Q000175:diagnosis; D006229:Hand Dermatoses / Q000175:diagnosis; D006801:Humans; D017488:Hyperkeratosis, Epidermolytic / Q000473:pathology; D007645:Keratoderma, Palmoplantar / Q000175:diagnosis* / Q000235:genetics