title: [Pathogenesis of invasive fungal infections].
abstract: Invasive fungal infections remain a life-threatening disease. The development of invasive fungal disease is dependent on multiple factors, such us colonization and efficient host immune response. We aimed to review the pathogenesis of invasive fungal infections, in particular, those caused by Candida and Aspergillus. For this we propose, to describe the fungal characteristics, to detail the host defence mechanisms against fungus and to analyse the host risk factors for invasive fungal infection.
authors.affiliation: Servicio de Enfermedades Infecciosas, Hospital Universitari de Bellvitge, Institut d'Investigació Biomèdica de Bellvitge (IDIBELL), Universitat de Barcelona, L'Hospitalet del Llobregat, Barcelona, España. carolgv75@hotmail.com
authors.forename: Carolina
authors.initials: C
authors.lastname: Garcia-Vidal
authors.forename: Jordi
authors.initials: J
authors.lastname: Carratalà
mesh_terms: D056704:Adaptive Immunity; D000305:Adrenal Cortex Hormones / Q000502:physiology; D000908:Antibodies, Fungal / Q000096:biosynthesis; D001228:Aspergillosis / Q000209:etiology / Q000276:immunology / Q000382:microbiology*; D001234:Aspergillus niger / Q000145:classification / Q000276:immunology / Q000472:pathogenicity; D002175:Candida / Q000145:classification / Q000276:immunology / Q000472:pathogenicity; D058365:Candidiasis, Invasive / Q000209:etiology / Q000276:immunology / Q000382:microbiology*; D016207:Cytokines / Q000502:physiology; D016469:Fungemia / Q000209:etiology / Q000276:immunology / Q000382:microbiology*; D054884:Host-Pathogen Interactions; D006801:Humans; D007113:Immunity, Innate; D016867:Immunocompromised Host; D007962:Leukocytes / Q000276:immunology; D016131:Lymphocyte Subsets / Q000276:immunology; D008264:Macrophages / Q000276:immunology; D010587:Phagocytosis; D051193:Toll-Like Receptors / Q000502:physiology
chemical_list: D000305:Adrenal Cortex Hormones; D000908:Antibodies, Fungal; D016207:Cytokines; D051193:Toll-Like Receptors