title: [Outstanding problems of normal and pathological morphology of the diffuse endocrine system].
abstract: The diffuse endocrine system (DES)--a mosaic-cellular endoepithelial gland--is the biggest part of the human endocrine system. Scientists used to consider cells of DES as neuroectodermal. According to modem data cells of DES are different cytogenetic types because they develop from the different embryonic blastophyllum. So that any hormone-active tumors originated from DES of the digestive, respiratory and urogenital system shouldn't be considered as neuroendocrinal tumors. The basic problems of DES morphology and pathology are the creation of scientifically substantiated histogenetic classification of DES tumors.
authors.forename: V V
authors.initials: VV
authors.lastname: Iaglov
authors.forename: N V
authors.initials: NV
authors.lastname: Iaglova
mesh_terms: D000818:Animals; D004701:Endocrine Gland Neoplasms / Q000145:classification / Q000378:metabolism / Q000473:pathology / Q000503:physiopathology; D004703:Endocrine System / Q000378:metabolism* / Q000473:pathology* / Q000503:physiopathology*; D006801:Humans