title: [Study on adverse drug reaction in Yuixngcao injection literatures].
abstract: Yuxingcao injection was suspended by China State Food and Drug Administration in 2006 for its severe adverse reaction in clinical practice. Althoug there are many real factors resulted in Yuxingcao injection's adverse reaction, some confounding factors should not be ignored. This study searched different kinds of related literatures and found out irregularity in defining dosage, disuses courses, indications and administration approach, which were the potential factors that caused the reported adverse drug reaction for Yuxingcao injection. And 97.8% adverse drug reaction in Yuxingcao injection happened 30 minutes after patients received administion, hence, observing patients'reaction in the first 30 minutes should be very important to prevent severe adverse drug reaction.
authors.affiliation: Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, China. wzhftcm@163.com
authors.forename: Zhifei
authors.initials: Z
authors.lastname: Wang
authors.forename: Yanming
authors.initials: Y
authors.lastname: Xie
authors.forename: Yongyan
authors.initials: Y
authors.lastname: Wang
mesh_terms: D004359:Drug Therapy, Combination; D064420:Drug-Related Side Effects and Adverse Reactions; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D007267:Injections
chemical_list: D004365:Drugs, Chinese Herbal