title: Chiral bicyclic [2.2.2] octadiene ligands for Rh-catalysed catalytic asymmetric conjugate additions to acyclic enones: a quantitative structure-property relationship.
abstract: A series of chiral bicyclic [2.2.2]diene ligands gave variable ee values for Rh-catalysed asymmetric conjugate addition to an acyclic enone. The interplay between electronic and steric effects was captured in a robust predictive quantitative structure-property relationship (QSPR) model for enantioselectivity.
authors.affiliation: Department of Chemistry, University of Liverpool, Crown Street, Liverpool, L69 7ZD, UK.
authors.forename: Yunfei
authors.initials: Y
authors.lastname: Luo
authors.forename: Neil G
authors.initials: NG
authors.lastname: Berry
authors.forename: Andrew J
authors.initials: AJ
authors.lastname: Carnell