title: Self-assembled coordination nanoparticles from nucleotides and lanthanide ions with doped-boronic acid-fluorescein for detection of cyanide in the presence of Cu2+ in water.
abstract: The sensor molecule, F-oBOH, containing boronic acid-linked hydrazide and fluorescein moieties was synthesized. For anion sensing applications, F-oBOH was studied in aqueous media. Unfortunately, F-oBOH was found to be hydrolyzed in water. Therefore, a new strategy was developed to prevent the hydrolysis of F-oBOH by applying self-assembly coordination nanoparticles network (F-oBOH-AMP/Gd(3+) CNPs). Interestingly, the nanoparticles network displayed the enhancement of fluorescent signal after adding Cu(2+) following by CN(-). The network, therefore, possessed a high selectivity for detection of CN(-) compared to other competitive anions in the presence of Cu(2+). Cyanide ion could promote the Cu(2+) binding to F-oBOH incorporated in AMP/Gd(3+) CNPs to give the opened-ring form of spirolactam resulting in the fourfold of fluorescence enhancement compared to Cu(2+) complexation without CN(-). Additionally, the log K value of F-oBOH-AMP/Gd(3+) CNPs⊂Cu(2+) toward CN(-) was 3.97 and the detection limits obtained from naked-eye and spectrofluorometry detections were 20μM and 4.03μM, respectively. The proposed method was demonstrated to detect CN(-) in drinking water with high accuracy.
authors.affiliation: Supramolecular Chemistry Research Unit, Department of Chemistry, Faculty of Science, Chulalongkorn University, 10330 Bangkok, Thailand.
authors.forename: Sirinan
authors.initials: S
authors.lastname: Kulchat
authors.forename: Anusak
authors.initials: A
authors.lastname: Chaicham
authors.forename: Sanong
authors.initials: S
authors.lastname: Ekgasit
authors.forename: Gamolwan
authors.initials: G
authors.lastname: Tumcharern
authors.forename: Thawatchai
authors.initials: T
authors.lastname: Tuntulani
authors.forename: Boosayarat
authors.initials: B
authors.lastname: Tomapatanaget
mesh_terms: D000249:Adenosine Monophosphate / Q000737:chemistry; D015374:Biosensing Techniques; D001897:Boronic Acids / Q000737:chemistry*; D003300:Copper / Q000737:chemistry*; D003486:Cyanides / Q000032:analysis*; D060766:Drinking Water / Q000737:chemistry*; D019793:Fluorescein; D005456:Fluorescent Dyes; D005682:Gadolinium / Q000737:chemistry; D007477:Ions; D028581:Lanthanoid Series Elements / Q000737:chemistry*; D057230:Limit of Detection; D053758:Nanoparticles / Q000737:chemistry*; D009711:Nucleotides / Q000737:chemistry*; D013050:Spectrometry, Fluorescence; D014874:Water Pollutants, Chemical / Q000032:analysis*
chemical_list: D001897:Boronic Acids; D003486:Cyanides; D060766:Drinking Water; D005456:Fluorescent Dyes; D007477:Ions; D028581:Lanthanoid Series Elements; D009711:Nucleotides; D014874:Water Pollutants, Chemical; D000249:Adenosine Monophosphate; D003300:Copper; D005682:Gadolinium; D019793:Fluorescein