title: Pathogens chipping away at our last line of defence - the rise of the metallo-beta-lactamases.
abstract: We describe the first known report of a VIM1 metallo-beta-lactamase-producing Klebsiella pneumonia outside Europe - confirmed by our colleagues in Canada. The patient had no travel history and surveillance failed to identify additional cases. The importance of health care professionals being diligent in identifying these multi-drug resistant isolates is emphasised.
authors.forename: Johan
authors.initials: J
authors.lastname: Moolman
authors.forename: Johann
authors.initials: J
authors.lastname: Pitout
mesh_terms: D034841:Abdominal Cavity / Q000382:microbiology; D000368:Aged; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D003082:Colectomy / Q000009:adverse effects*; D004239:Diverticulitis, Colonic / Q000601:surgery; D017809:Fatal Outcome; D006801:Humans; D007710:Klebsiella Infections / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology*; D007711:Klebsiella pneumoniae / Q000201:enzymology / Q000302:isolation & purification; D008297:Male; D008826:Microbial Sensitivity Tests; D011183:Postoperative Complications; D013019:South Africa; D013492:Suppuration / Q000382:microbiology*; D018440:beta-Lactam Resistance; D001618:beta-Lactamases / Q000096:biosynthesis
chemical_list: D000900:Anti-Bacterial Agents; C417264:VIM-1 metallo-beta-lactamase; D001618:beta-Lactamases