title: Therapeutic apheresis in children: special considerations.
abstract: The provision of therapeutic apheresis to children is a technically challenging procedure, requiring trained personnel and an understanding of the disease processes that leads to the need for apheresis. Most apheresis protocols are derived from studies in adult patients, even though most studies are of limited sample size. The focus of this review is to highlight the disease processes commonly treated with therapeutic apheresis in children, and to address the technical considerations pertinent to the provision of safe and effective apheresis in the pediatric setting.
authors.affiliation: Department of Pediatrics, University of Cincinnati College of Medicine and the Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45206, USA. stuart.goldstein@cchmc.org
authors.forename: Stuart L
authors.initials: SL
authors.lastname: Goldstein
mesh_terms: D000367:Age Factors; D001781:Blood Component Removal / Q000009:adverse effects / Q000379:methods* / Q000401:mortality*; D002648:Child; D002675:Child, Preschool; D016638:Critical Illness / Q000628:therapy*; D004673:Encephalomyelitis, Acute Disseminated / Q000175:diagnosis / Q000628:therapy*; D005260:Female; D020275:Guillain-Barre Syndrome / Q000175:diagnosis / Q000628:therapy; D006776:Hospitals, Pediatric; D006801:Humans; D007674:Kidney Diseases / Q000175:diagnosis / Q000628:therapy; D008297:Male; D009102:Multiple Organ Failure / Q000175:diagnosis / Q000401:mortality / Q000628:therapy; D061214:Patient Safety; D018579:Patient Selection; D010372:Pediatrics; D011379:Prognosis; D018570:Risk Assessment; D018805:Sepsis / Q000175:diagnosis / Q000628:therapy; D015996:Survival Rate; D016896:Treatment Outcome