title: A 1-year follow-up of a multi-center treatment trial of adults with anorexia nervosa.
abstract: OBJECTIVE
  To examine maintenance of recovery following treatment in an adult anorexia nervosa (AN) population.
  
  
  METHODS
  One year follow-up of a randomized clinical trial with 122 participants treated with: cognitive behavioral therapy (CBT), drug therapy (fluoxetine), or a combination (CBT+fluoxetine) for 12 months. Participants were assessed at baseline, end of treatment, and follow-up. The primary outcomes were weight and the global scores from the Eating Disorder Examination (EDE) separately and combined.
  
  
  RESULTS
  Fifty-two participants completed the follow-up. Mean weight increased from end of treatment to follow-up. Seventy-five percent (75%) of those weight recovered at end of treatment maintained this recovery at follow-up. Recovery of eating disorder psychopathology was stable from end of treatment to follow-up, with 40% of participants with a global EDE score within normal range. Using the most stringent criteria for recovery, only 21% of the completer sample was recovered.
  
  
  CONCLUSIONS
  The findings suggest that while adults with AN improve with treatment and maintain these improvements during follow-up, the majority is not recovered. Additionally, further research is needed to understand barriers to treatment and assessment completion.
authors.affiliation: Department of Psychiatry, Stanford University School of Medicine, Stanford, CA 94305-5722, USA. jessica.samantha.yu@gmail.com
authors.forename: J
authors.initials: J
authors.lastname: Yu
authors.forename: W
authors.initials: W
authors.lastname: Stewart Agras
authors.forename: K A
authors.initials: KA
authors.lastname: Halmi
authors.forename: S
authors.initials: S
authors.lastname: Crow
authors.forename: J
authors.initials: J
authors.lastname: Mitchell
authors.forename: S W
authors.initials: SW
authors.lastname: Bryson
mesh_terms: D000328:Adult; D000856:Anorexia Nervosa / Q000188:drug therapy / Q000523:psychology / Q000628:therapy*; D001835:Body Weight; D015928:Cognitive Behavioral Therapy; D003131:Combined Modality Therapy; D005260:Female; D005473:Fluoxetine / Q000627:therapeutic use*; D005500:Follow-Up Studies; D006801:Humans; D010551:Personality; D011569:Psychiatric Status Rating Scales; D012649:Self Concept; D017367:Selective Serotonin Reuptake Inhibitors / Q000627:therapeutic use*; D011795:Surveys and Questionnaires; D016896:Treatment Outcome
chemical_list: D005473:Fluoxetine; D017367:Selective Serotonin Reuptake Inhibitors