title: Anesthetic management of patients undergoing pulmonary vein isolation for treatment of atrial fibrillation using high-frequency jet ventilation.
abstract: OBJECTIVE
  The aim of this study was to describe anesthetic management and perioperative complications in patients undergoing pulmonary vein isolation for the treatment of atrial fibrillation under general anesthesia using high-frequency jet ventilation. The authors also identified variables associated with longer ablation times in this patient cohort.
  
  
  METHODS
  A retrospective observational study.
  
  
  METHODS
  The electrophysiology laboratory in a major university hospital.
  
  
  METHODS
  One hundred eighty-eight consecutive patients undergoing pulmonary vein isolation under general anesthesia with high-frequency jet ventilation.
  
  
  METHODS
  High-frequency jet ventilation was used as the primary mode of ventilation under general anesthesia.
  
  
  RESULTS
  High-frequency jet ventilation was performed successfully throughout the ablation procedure in 175 cases of the study cohort. The remaining 13 patients had to be converted to conventional positive-pressure ventilation because of high PaCO(2) or low PaO(2) on arterial blood gas measurements. Variables associated with a shorter ablation time included a higher ejection fraction (p = 0.04) and case volume performed by each electrophysiologist in the study group (p = 0.001).
  
  
  CONCLUSIONS
  High-frequency jet ventilation is generally a safe technique that can be used in catheter ablation treatment under general anesthesia.
authors.affiliation: Department of Anesthesiology and Critical Care, University of Pennsylvania, Philadelphia, PA 19104, USA. nabil.elkassabany@uphs.upenn.edu
authors.forename: Nabil
authors.initials: N
authors.lastname: Elkassabany
authors.forename: Fermin
authors.initials: F
authors.lastname: Garcia
authors.forename: Cory
authors.initials: C
authors.lastname: Tschabrunn
authors.forename: Jesse
authors.initials: J
authors.lastname: Raiten
authors.forename: William
authors.initials: W
authors.lastname: Gao
authors.forename: Khan
authors.initials: K
authors.lastname: Chaichana
authors.forename: Sanjay
authors.initials: S
authors.lastname: Dixit
authors.forename: Rebecca M
authors.initials: RM
authors.lastname: Speck
authors.forename: Erica
authors.initials: E
authors.lastname: Zado
authors.forename: Francis
authors.initials: F
authors.lastname: Marchlinski
authors.forename: Jeff
authors.initials: J
authors.lastname: Mandel
mesh_terms: D000368:Aged; D000768:Anesthesia, General / Q000379:methods*; D001281:Atrial Fibrillation / Q000601:surgery*; D015992:Body Mass Index; D002245:Carbon Dioxide / Q000097:blood; D017115:Catheter Ablation / Q000379:methods*; D005260:Female; D006611:High-Frequency Jet Ventilation / Q000009:adverse effects / Q000379:methods*; D006801:Humans; D007432:Intraoperative Period; D008297:Male; D008875:Middle Aged; D010100:Oxygen / Q000097:blood; D010313:Partial Pressure; D011667:Pulmonary Veins / Q000601:surgery*; D012189:Retrospective Studies
chemical_list: D002245:Carbon Dioxide; D010100:Oxygen