title: Polyvascular disease in patients presenting with acute coronary syndrome: its predictors and outcomes.
abstract: We evaluated prevalence and clinical outcome of polyvascular disease (PolyVD) in patients presenting with acute coronary syndrome (ACS). Data for 7689 consecutive ACS patients were collected from the 2nd Gulf Registry of Acute Coronary Events between October 2008 and June 2009. Patients were divided into 2 groups (ACS with versus without PolyVD). All-cause mortality was assessed at 1 and 12 months. Patients with PolyVD were older and more likely to have cardiovascular risk factors. On presentation, those patients were more likely to have atypical angina, high resting heart rate, high Killip class, and GRACE risk scoring. They were less likely to receive evidence-based therapies. Diabetes mellitus, renal failure, and hypertension were independent predictors for presence of PolyVD. PolyVD was associated with worse in-hospital outcomes (except for major bleedings) and all-cause mortality even after adjusting for baseline covariates. Great efforts should be directed toward primary and secondary preventive measures.
authors.affiliation: Department of Cardiology and Cardiovascular Surgery, Hamad General Hospital, Doha 3050, Qatar. althanih@hotmail.com
authors.forename: Hassan
authors.initials: H
authors.lastname: Al Thani
authors.forename: Ayman
authors.initials: A
authors.lastname: El-Menyar
authors.forename: Khalid F
authors.initials: KF
authors.lastname: Alhabib
authors.forename: Ahmed
authors.initials: A
authors.lastname: Al-Motarreb
authors.forename: Ahmad
authors.initials: A
authors.lastname: Hersi
authors.forename: Hussam
authors.initials: H
authors.lastname: Alfaleh
authors.forename: Nidal
authors.initials: N
authors.lastname: Asaad
authors.forename: Shukri Al
authors.initials: SA
authors.lastname: Saif
authors.forename: Wael
authors.initials: W
authors.lastname: Almahmeed
authors.forename: Kadhim
authors.initials: K
authors.lastname: Sulaiman
authors.forename: Haitham
authors.initials: H
authors.lastname: Amin
authors.forename: Alawi A
authors.initials: AA
authors.lastname: Alsheikh-Ali
authors.forename: Khalid
authors.initials: K
authors.lastname: Alnemer
authors.forename: Jassim Al
authors.initials: JA
authors.lastname: Suwaidi
mesh_terms: D054058:Acute Coronary Syndrome / Q000150:complications* / Q000401:mortality; D002561:Cerebrovascular Disorders / Q000150:complications / Q000453:epidemiology; D003324:Coronary Artery Disease / Q000150:complications / Q000453:epidemiology; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D008877:Middle East / Q000453:epidemiology; D016491:Peripheral Vascular Diseases / Q000150:complications / Q000453:epidemiology; D015995:Prevalence; D011446:Prospective Studies; D012307:Risk Factors; D012737:Sex Factors; D016896:Treatment Outcome; D014652:Vascular Diseases / Q000150:complications* / Q000453:epidemiology