title: [The effect of infrared and X-ray radiation on the production of reactive oxygen species in blood and induction of cytogenetic damage in the bone marrow of mice in vivo].
abstract: The goal of the present work was to study the effect of infrared light (IRL) at a wavelength of 850 nm modulated by a frequency of 101 Hz with a mode of power 22 mW/cm2 and X-rays with a voltage of 200 kV at a dose rate of 1 Gy/min on the production of reactive oxygen species (ROS) in blood cells using luminol-dependent chemiluminescence, as well as on the induction of a cytogenetic damage in bone marrow cells of mice by the in vivo micronucleus test. The experiments performed have shown: 1) the level of the ROS production in blood of the mice exposed to IRL and X-rays at an adapting dose of 0.1 Gy reaches the peak value after 0.5 h and drops to the ROS level in untreated animals 5 h after either exposure; 2) irradiation of mice with IRL and X-rays at a dose of 0.1 Gy induces adaptive responses both in blood cells and bone marrow cells of mice. These adaptive responses were revealed only 5 h after both exposures, when the level of ROS production decreased to the ROS level in untreated animals; they are equal in magnitude and dynamics and persist up to 2 months.
authors.forename: A R
authors.initials: AR
authors.lastname: Diukina
authors.forename: S I
authors.initials: SI
authors.lastname: Zaichkina
authors.forename: O M
authors.initials: OM
authors.lastname: Rozanova
authors.forename: S P
authors.initials: SP
authors.lastname: Romanchenko
authors.forename: V N
authors.initials: VN
authors.lastname: Mal'tseva
authors.forename: G F
authors.initials: GF
authors.lastname: Aptikaeva
mesh_terms: D000222:Adaptation, Physiological / Q000528:radiation effects; D000818:Animals; D001854:Bone Marrow Cells / Q000528:radiation effects* / Q000648:ultrastructure; D004307:Dose-Response Relationship, Radiation; D007259:Infrared Rays / Q000009:adverse effects*; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D048629:Micronuclei, Chromosome-Defective / Q000528:radiation effects*; D015162:Micronucleus Tests; D017382:Reactive Oxygen Species / Q000097:blood*; D013997:Time Factors; D014965:X-Rays / Q000009:adverse effects*
chemical_list: D017382:Reactive Oxygen Species