title: Human papillomavirus (HPV) detection and Papanicolaou cytology in low-resource women in Posadas city, Misiones, Argentina.
abstract: The objective of this study was to determine the prevalence of HPV infection and cervical lesions present in women who attended a health center in a low-resource area of the city of Posadas, Misiones, Argentina. Cervical cell samples (n = 163) were processed for Papanicolaou cytology and HPV-PCR tests. Socio-cultural risk factors were estimated using the odds ratio (OR, CI 95 %). Cervical lesions were detected in 14.7 % of women. The general prevalence of HPV infection was of 38 %. The most common types among the total population were HPV-16 (9.8 %) and HPV-33 (9.3 %). HPV-16 was detected in association with 29.2 % and 6.5 % of women with and without cervical lesions, respectively, the OR being 5.3 (1.8-15.8). Risk factors for HPV-16 infection were a smoking habit and a history of previous sexually-transmitted diseases. These data are important for the implementation of prevention programs, including an appropriate introduction of vaccination and the baseline for virological surveillance in the vaccine era.
authors.affiliation: Universidad Nacional de Misiones, Posadas, Misiones.
authors.forename: Inés
authors.initials: I
authors.lastname: Badano
authors.forename: René W
authors.initials: RW
authors.lastname: Pedrozo
authors.forename: Laura S
authors.initials: LS
authors.lastname: Ruíz Díaz
authors.forename: Juan A
authors.initials: JA
authors.lastname: Galuppo
authors.forename: María A
authors.initials: MA
authors.lastname: Picconi
authors.forename: Rodolfo H
authors.initials: RH
authors.lastname: Campos
authors.forename: Domingo J
authors.initials: DJ
authors.lastname: Liotta
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D052685:Alphapapillomavirus / Q000235:genetics / Q000302:isolation & purification*; D001118:Argentina; D015344:DNA Probes, HPV; D005260:Female; D052162:Human papillomavirus 16 / Q000302:isolation & purification; D006801:Humans; D008875:Middle Aged; D016017:Odds Ratio; D065006:Papanicolaou Test; D030361:Papillomavirus Infections / Q000453:epidemiology*; D011203:Poverty; D015995:Prevalence; D012307:Risk Factors; D012725:Sexual Behavior; D012749:Sexually Transmitted Diseases / Q000453:epidemiology; D012907:Smoking / Q000453:epidemiology; D014505:Urban Population; D002575:Uterine Cervicitis / Q000453:epidemiology* / Q000821:virology; D014626:Vaginal Smears; D055815:Young Adult
chemical_list: D015344:DNA Probes, HPV