title: Understanding metastasis in pancreatic cancer: a call for new clinical approaches.
abstract: Although metastasis is a major cause of morbidity and mortality in patients with pancreatic cancer, the requisite events are currently unknown. In this issue of Cell, Haeno et al. and Rhim et al. propose that metastasis occurs much earlier than previously anticipated, with clear implications for improving patient care.
authors.affiliation: Li Ka Shing Centre, Cancer Research UK Cambridge Research Institute, Robinson Way, Cambridge CB2 0RE, UK. david.tuveson@cancer.org.uk
authors.forename: David A
authors.initials: DA
authors.lastname: Tuveson
authors.forename: John P
authors.initials: JP
authors.lastname: Neoptolemos