title: The influence of microwave radiation from cellular phone on fetal rat brain.
abstract: The increasing use of cellular phones in our society has brought focus on the potential detrimental effects to human health by microwave radiation. The aim of our study was to evaluate the intensity of oxidative stress and the level of neurotransmitters in the brains of fetal rats chronically exposed to cellular phones. The experiment was performed on pregnant rats exposed to different intensities of microwave radiation from cellular phones. Thirty-two pregnant rats were randomly divided into four groups: CG, GL, GM, and GH. CG accepted no microwave radiation, GL group radiated 10 min each time, GM group radiated 30 min, and GH group radiated 60 min. The 3 experimental groups were radiated 3 times a day from the first pregnant day for consecutively 20 days, and on the 21st day, the fetal rats were taken and then the contents of superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), malondialdehyde (MDA), noradrenaline (NE), dopamine (DA), and 5-hydroxyindole acetic acid (5-HT) in the brain were assayed. Compared with CG, there were significant differences (P<0.05) found in the contents of SOD, GSH-Px, and MDA in GM and GH; the contents of SOD and GSH-Px decreased and the content of MDA increased. The significant content differences of NE and DA were found in fetal rat brains in GL and GH groups, with the GL group increased and the GH group decreased. Through this study, we concluded that receiving a certain period of microwave radiation from cellular phones during pregnancy has certain harm on fetal rat brains.
authors.affiliation: Institute of Chemistry and Bacteria Detection, Department of Public Health, Shandong University, and Department of Radiology, Shandong Qianfoshan Hospital, Shandong, China.
authors.forename: Ji
authors.initials: J
authors.lastname: Jing
authors.forename: Zhang
authors.initials: Z
authors.lastname: Yuhua
authors.forename: Yang
authors.initials: Y
authors.lastname: Xiao-qian
authors.forename: Jiang
authors.initials: J
authors.lastname: Rongping
authors.forename: Guo
authors.initials: G
authors.lastname: Dong-mei
authors.forename: Cui
authors.initials: C
authors.lastname: Xi
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000378:metabolism; D001921:Brain / Q000196:embryology* / Q000201:enzymology / Q000378:metabolism / Q000528:radiation effects*; D040421:Cell Phone; D004298:Dopamine / Q000378:metabolism; D004574:Electromagnetic Fields / Q000009:adverse effects; D005260:Female; D005333:Fetus / Q000166:cytology / Q000201:enzymology / Q000378:metabolism / Q000528:radiation effects*; D005979:Glutathione Peroxidase / Q000378:metabolism; D006801:Humans; D006897:Hydroxyindoleacetic Acid / Q000378:metabolism; D008297:Male; D008315:Malondialdehyde / Q000378:metabolism; D008872:Microwaves / Q000009:adverse effects*; D018377:Neurotransmitter Agents / Q000378:metabolism; D009638:Norepinephrine / Q000378:metabolism; D011247:Pregnancy; D051381:Rats; D017208:Rats, Wistar; D013482:Superoxide Dismutase / Q000378:metabolism
chemical_list: D000975:Antioxidants; D018377:Neurotransmitter Agents; D008315:Malondialdehyde; D006897:Hydroxyindoleacetic Acid; D005979:Glutathione Peroxidase; D013482:Superoxide Dismutase; D004298:Dopamine; D009638:Norepinephrine