title: Rising complication rates after intrathecal catheter and pump placement in the pediatric population: analysis of national data between 1997 and 2006.
abstract: BACKGROUND
  Intrathecal delivery of baclofen (ITB) is effective at controlling spasticity. However, it requires the placement of a catheter into the intrathecal space, and a pump with a reservoir for the medication. The process of placing the catheter and pump are prone to complications.
  
  
  OBJECTIVE
  The objective of this paper is to determine factors contributing to rising complication rates after intrathecal catheter/pump placement in a national sample of pediatric patients.
  
  
  METHODS
  This was a retrospective observational database study.
  
  
  METHODS
  We queried the Kids' Inpatient Database for all children greater than 4 years old and under 20 years old for the years 1997, 2000, 2003, and 2006 who had an intrathecal catheter and pump placed. We then compared demographics and hospital characteristics of patients with and without complications. We performed univariate and multivariate analyses to determine the relative contribution of various factors to the development of complications.
  
  
  RESULTS
  We identified 2,843 patients who met our criteria, and 514 of these patients had one or more complications after placement of intrathecal pump/catheter. There were 1.14 complications per patient. The complication rate was 10.2% in 1997, and increased to 21.9% in 2006. Mechanical complications were the most common type of complication in this population, account for nearly two-thirds of all complications occurring. Age, hospital type, hospital size, and admission source were independent predictors of complications.
  
  
  CONCLUSIONS
  We did not have access to ASA status, operative details, and access to patient charts.
  
  
  CONCLUSIONS
  Complication rates after placement of intrathecal pump/catheters have increased in the pediatric population between 1997 and 2006 mainly due to an increase in mechanical complications.
authors.affiliation: University of Virginia, Charlottesville, VA 22908-0710, USA.
authors.forename: Narayana C
authors.initials: NC
authors.lastname: Varhabhatla
authors.forename: Zhiyi
authors.initials: Z
authors.lastname: Zuo
mesh_terms: D000293:Adolescent; D001418:Baclofen / Q000008:administration & dosage; D002404:Catheterization / Q000009:adverse effects*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D015918:Infusion Pumps, Implantable / Q000009:adverse effects*; D060186:Infusions, Spinal / Q000009:adverse effects*; D008297:Male; D009125:Muscle Relaxants, Central / Q000008:administration & dosage; D009128:Muscle Spasticity / Q000188:drug therapy; D019635:Neurosurgical Procedures / Q000009:adverse effects*; D011183:Postoperative Complications; D014481:United States; D055815:Young Adult
chemical_list: D009125:Muscle Relaxants, Central; D001418:Baclofen