title: Philadelphia Brief Assessment of Cognition in healthy and clinical Brazilian sample.
abstract: The Philadelphia Brief Assessment of Cognition (PBAC) is a neuropsychological screening instrument that assesses five cognitive domains: working memory, visuospatial functioning, language, episodic memory and comportment. The aim is to verify if PBAC can properly be used in the Brazilian sample. Participated in this study: (a) 200 healthy volunteers - 100 young [21.6(2.5) years old] and 100 older adults [70.1(7.3) years old]; >12 years of education; (b) 30 Alzheimer's patients (AD) [73.7(5.7) years old], 4-11 years in education. The PBAC scores: (a) 95.8(2.6), 90.0(4.4) and (b) 65.0(10.8) were correlated with the Mini-Mental State Examination (MMSE) for young 29.1(0.9), older adults 28.3(1.4) and AD 18.4(3.0) groups. A positive correlation between MMSE and PBAC (r=0.9, p<0.001) was found. Negative correlations were observed between PBAC domains [memory (-0.63), visuospatial abilities (-0.44) and working memory (-0.3) tasks]. MANOVA showed a better male performance in visuospatial functioning (F=8.5, p=0.004). The Brazilian version of PBAC proved to be a promising screening instrument for clinical purposes.
authors.affiliation: Brazilian Institute of Neuropsychology and Cognitive Sciences, Brasília, DF, Brazil.
authors.forename: Danilo Assis
authors.initials: DA
authors.lastname: Pereira
authors.forename: Corina
authors.initials: C
authors.lastname: Satler
authors.forename: Luciana
authors.initials: L
authors.lastname: Medeiros
authors.forename: Renan
authors.initials: R
authors.lastname: Pedroso
authors.forename: Carlos
authors.initials: C
authors.lastname: Tomaz
mesh_terms: D000328:Adult; D000368:Aged; D000544:Alzheimer Disease / Q000175:diagnosis* / Q000503:physiopathology; D001938:Brazil; D004522:Educational Status; D005260:Female; D006801:Humans; D008297:Male; D008570:Memory, Short-Term / Q000502:physiology*; D008609:Mental Status Schedule; D011594:Psychometrics; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012919:Social Behavior; D013028:Space Perception / Q000502:physiology*; D014706:Verbal Learning / Q000502:physiology*; D055815:Young Adult