title: Stroke. Geometry is destiny for carotid atherosclerotic plaques.
abstract: The geometry of carotid arteries, both normal and narrowed, produces flow characteristics that predict the location of atherosclerosis and the site of plaque rupture. A recent study has shown that the upstream carotid plaque undergoes profound biochemical and apoptotic changes that are closely linked to the development of stroke symptoms.
authors.affiliation: Department of Neurology, Anatomy & Neurobiology, and Pathology & Laboratory Medicine, University of California Irvine School of Medicine, 101 The City Drive South, Orange, CA 92868, USA. mfisher@uci.edu
authors.forename: Mark
authors.initials: M
authors.lastname: Fisher
mesh_terms: D050197:Atherosclerosis / Q000503:physiopathology*; D002339:Carotid Arteries / Q000503:physiopathology*; D002340:Carotid Artery Diseases / Q000503:physiopathology*; D006439:Hemodynamics / Q000502:physiology*; D006801:Humans; D058226:Plaque, Atherosclerotic / Q000503:physiopathology*