title: Total synthsis of (+)-ambuic acid: α-bromination with 1,2-dibromotetrachloroethane.
abstract: Total synthesis of (+)-ambuic acid has been accomplished from the readily available stereocontrolled Diels-Alder adduct of cyclopentadiene and iodo-1,4-benzoquinone monoketal through an efficient series of steps. A new method for the highly commendable synthesis of α-brominated Diels-Alder adduct is described.
authors.affiliation: Department of Chemistry, Sungkyunkwan University, Suwon 440-746, Korea.
authors.forename: Sun Hee
authors.initials: SH
authors.lastname: Jung
authors.forename: Geum-Sook
authors.initials: GS
authors.lastname: Hwang
authors.forename: Sung Il
authors.initials: SI
authors.lastname: Lee
authors.forename: Do Hyun
authors.initials: DH
authors.lastname: Ryu
mesh_terms: D064228:Bromochlorofluorocarbons; D005617:Chlorofluorocarbons, Methane / Q000737:chemistry*; D003512:Cyclohexanones / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D013237:Stereoisomerism; D005466:Fluorocarbons
chemical_list: D064228:Bromochlorofluorocarbons; D005617:Chlorofluorocarbons, Methane; D003512:Cyclohexanones; C429363:ambuic acid; C007784:1,2-dibromotetrafluoroethane; D005466:Fluorocarbons