title: An alternative approach to para-C-H arylation of phenol: palladium-catalyzed tandem γ-arylation/aromatization of 2-cyclohexen-1-one derivatives.
abstract: An efficient approach to prepare para-aryl phenols has been developed by using a Pd-catalyzed tandem γ-arylation/aromatization of 2-cyclohexen-1-one derivatives with aryl bromides. This approach provides various p-aryl phenols from the phenol surrogates, 2-cyclohexen-1-one derivatives, in a single reaction step on the basis of C-H arylation.
authors.affiliation: Priority Organization for Innovation and Excellence, Kumamoto University, 2-39-1 Kurokami, Kumamoto 860-8555, Japan. imahori@kumamoto-u.ac.jp
authors.forename: Tatsushi
authors.initials: T
authors.lastname: Imahori
authors.forename: Toru
authors.initials: T
authors.lastname: Tokuda
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Taguchi
authors.forename: Hiroki
authors.initials: H
authors.lastname: Takahata
mesh_terms: D002384:Catalysis; D003512:Cyclohexanones / Q000737:chemistry*; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*; D019800:Phenol / Q000737:chemistry*
chemical_list: D003512:Cyclohexanones; D019800:Phenol; C028215:2-cyclohexen-1-one; D010165:Palladium