title: The human salivary proteome: a critical overview of the results obtained by different proteomic platforms.
abstract: The development of new separation techniques and different mass spectrometry instrumental devices, as well as the great availability of specific reactants, offers ample choice to scientists for carrying out high-throughput proteomic studies and being competitive in the field today. However, the different options available often do not provide comparable results, which can be linked to factors such as the strategy adopted, the nature of the sample and the instrumental availability. In this critical review, the results obtained so far in the study of human saliva by different proteomic approaches will be compared and discussed.
authors.affiliation: Istituto di Biochimica e di Biochimica Clinica, Facoltà di Medicina, Università Cattolica, Largo F. Vito, 00168, Roma, Italy. massimo.castagnola@icrm.cnr.it
authors.forename: Massimo
authors.initials: M
authors.lastname: Castagnola
authors.forename: Tiziana
authors.initials: T
authors.lastname: Cabras
authors.forename: Federica
authors.initials: F
authors.lastname: Iavarone
authors.forename: Chiara
authors.initials: C
authors.lastname: Fanali
authors.forename: Sonia
authors.initials: S
authors.lastname: Nemolato
authors.forename: Giusy
authors.initials: G
authors.lastname: Peluso
authors.forename: Silvia Laura
authors.initials: SL
authors.lastname: Bosello
authors.forename: Gavino
authors.initials: G
authors.lastname: Faa
authors.forename: Gianfranco
authors.initials: G
authors.lastname: Ferraccioli
authors.forename: Irene
authors.initials: I
authors.lastname: Messana
mesh_terms: D002851:Chromatography, High Pressure Liquid; D015180:Electrophoresis, Gel, Two-Dimensional; D006801:Humans; D020543:Proteome; D012463:Saliva / Q000737:chemistry*; D021241:Spectrometry, Mass, Electrospray Ionization; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
chemical_list: D020543:Proteome