title: In vitro and ex vivo studies of antioxidant activity of carrageenans, sulfated polysaccharides from red algae.
abstract: Antioxidant properties of structurally different sulfated polysaccharides (carrageenans) were studied in vitro and ex vivo. Ferric reducing antioxidant activity of carrageenans and their inhibitory effects on hydroxyl radicals and superoxide anion radicals were demonstrated in vitro. Activity of carrageenans depends on the polysaccharide structure. Carrageenans stimulate catalytic activity of SOD from donor erythrocyte.
authors.affiliation: Pacific Institute of Organic Biochemistry, Far-Eastern Division of the Russian Academy of Sciences, Vladivostok, Russia.
authors.forename: E V
authors.initials: EV
authors.lastname: Sokolova
authors.forename: A O
authors.initials: AO
authors.lastname: Barabanova
authors.forename: V A
authors.initials: VA
authors.lastname: Homenko
authors.forename: T F
authors.initials: TF
authors.lastname: Solov'eva
authors.forename: R N
authors.initials: RN
authors.lastname: Bogdanovich
authors.forename: I M
authors.initials: IM
authors.lastname: Yermak
mesh_terms: D000975:Antioxidants / Q000737:chemistry / Q000494:pharmacology*; D002351:Carrageenan / Q000737:chemistry / Q000494:pharmacology*; D004912:Erythrocytes / Q000187:drug effects / Q000201:enzymology; D016166:Free Radical Scavengers / Q000737:chemistry / Q000494:pharmacology; D006801:Humans; D017665:Hydroxyl Radical / Q000378:metabolism; D010084:Oxidation-Reduction; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology; D000461:Rhodophyta / Q000737:chemistry*; D013482:Superoxide Dismutase / Q000378:metabolism*; D013481:Superoxides / Q000378:metabolism
chemical_list: D000975:Antioxidants; D016166:Free Radical Scavengers; D010936:Plant Extracts; D013481:Superoxides; D017665:Hydroxyl Radical; D002351:Carrageenan; D013482:Superoxide Dismutase