title: [The quality of life if HIV/AIDS patients in Iasi Romania].
abstract: Quality of life in relation to health is a consequence of disease and treatment on the patient's perception of his ability to have a full and useful life. Due to its nature, the quality of life is a multidimensional and subjective construct, based on the patient's experience. We operationalized the quality of life using the following parameters: CD4 count and HIV viral levels in the patient's blood, the number of days of hospitalization, number of antiretroviral plans, types of side effects and their frequency, psychological issues (anxiety, depression, and neurotic tendencies).
  
  
  METHODS
  We centralized data from a total of 600 patients from the Regional Center in Iaşi in 2010-2011. Side effects accused by the patients emerged from discussions with the infectious disease doctor and psychologist, and psychological aspects were measured by specific instruments (PA Inventory, Beck Depression Scale).
  
  
  RESULTS
  Most patients enrolled in the study were male (59%) with mean age of 21.1 years. 34% of them came from rural areas. Average schooling level was 6 primary classes, with extremes between the two classes of primary and higher education. Only 14% of patients had a job, while the rest did not have a stable job or were not employed. 38% came from broken homes or foster care. 85% of patients were in therapy at the time of data centralization. 55% were in the second, third or fourth regimen. 25% were at their first scheme, while 10% in the seventh - eighth scheme. The mean CD4 count ranged between 13 and 269/mmc, while the average viral load varied between 1730 and 3.180.000/mmc. The average number of days of hospitalization was 4. Among the antiretroviral side effects patients complained nausea and vomiting in 85% of cases, lipodystrophy symptoms in 25% of cases, diarrhea 15%. With regard to psychological aspects, 65% of patients showed an above average level of anxiety, 40% showed depressive symptoms, while 10% had specific obsessions-compulsions, and 10% neurotic and hysterical tendencies.
  
  
  CONCLUSIONS
  By measuring the quality of life through the above parameters, we obtained a clear and comprehensive picture of the situation facing the HIV patient. We believe that close cooperation between the team of doctors and psychologists assisting the infectious patient, on the one hand, and specialists in other medical fields that interact with the patient, on the other hand, can enhance the quality of life of the HIV patient and maintain it at a comfortable level.
authors.affiliation: Disciplina de Boli Infecţioase, Facultatea de Medicină, Universitatea de Medicină şi Farmacie "Gr. T. Popa" Iaşi.
authors.forename: Carmen
authors.initials: C
authors.lastname: Manciuc
authors.forename: Alexandra
authors.initials: A
authors.lastname: Largu
authors.forename: A
authors.initials: A
authors.lastname: Vâţă
authors.forename: Cristina
authors.initials: C
authors.lastname: Nicolau
authors.forename: L
authors.initials: L
authors.lastname: Prisacaru
authors.forename: Daniela
authors.initials: D
authors.lastname: Stoica
authors.forename: Carmen
authors.initials: C
authors.lastname: Dorobăţ
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000188:drug therapy; D000328:Adult; D023241:Antiretroviral Therapy, Highly Active / Q000009:adverse effects / Q000379:methods; D001007:Anxiety / Q000523:psychology; D018791:CD4 Lymphocyte Count; D003863:Depression / Q000523:psychology; D003967:Diarrhea / Q000139:chemically induced; D018450:Disease Progression; D005260:Female; D015658:HIV Infections / Q000175:diagnosis / Q000188:drug therapy* / Q000453:epidemiology / Q000276:immunology; D006801:Humans; D007297:Inpatients / Q000706:statistics & numerical data; D007902:Length of Stay / Q000706:statistics & numerical data; D008297:Male; D009325:Nausea / Q000139:chemically induced; D011203:Poverty / Q000706:statistics & numerical data; D011788:Quality of Life; D012383:Romania / Q000453:epidemiology; D012424:Rural Population / Q000706:statistics & numerical data; D012720:Severity of Illness Index; D016896:Treatment Outcome; D014505:Urban Population / Q000706:statistics & numerical data; D019562:Viral Load