title: The utility of far-infrared illumination in oxygenation dynamics as measured with near-infrared spectroscopy.
abstract: Near-infrared spectroscopy (NIRS) is a noninvasive method for measuring the oxygenation in muscle and other tissues in vivo. For quantitative NIRS measurement of oxygenation dynamics, the vessel-occlusion test was usually applied as physiological intervention. There are several drawbacks of the vessel-occlusion method that include skin contact, uncomfortable and microcirculation block of patients. Thus, we propose the far-infrared (FIR) illumination as a new physiological intervention method in this paper. Our preliminary result shows a linear correlation of oxygenation dynamic signals between FIR illumination and arterial-occlusion test (AOT) that implies the FIR illumination could be applied for hemodynamic response measurement in clinical diagnosis.
authors.affiliation: Biophotonics and Molecular Imaging Research Center and Institute of Biophotonics, National Yang-Ming University, Taipei 11221, Taiwan, R.O.C.
authors.forename: Chun-Yang
authors.initials: CY
authors.lastname: Wang
authors.forename: Ming-Lung
authors.initials: ML
authors.lastname: Chuang
authors.forename: Ching-Cheng
authors.initials: CC
authors.lastname: Chuang
authors.forename: Yao-Sheng
authors.initials: YS
authors.lastname: Hsieh
authors.forename: Chia-Wei
authors.initials: CW
authors.lastname: Sun
mesh_terms: D015415:Biomarkers / Q000378:metabolism; D002319:Cardiovascular System / Q000378:metabolism; D006454:Hemoglobins / Q000378:metabolism; D006801:Humans; D007259:Infrared Rays; D010100:Oxygen / Q000378:metabolism*; D019265:Spectroscopy, Near-Infrared
chemical_list: D015415:Biomarkers; D006454:Hemoglobins; D010100:Oxygen