title: Cranial mediastinal liposarcoma in a horse.
abstract: A 23-year-old Anglo-Arabian mare was presented with tachypnea, dyspnea, and pitting edema of the ventral thoracic subcutis. On necropsy, a tan to red, friable, irregularly shaped mass (23 × 20 × 18 cm) occupied the cranial mediastinum. Histologically, the mass was classified as a liposarcoma and was composed of short interlacing bundles of spindle-shaped to irregularly rounded cells with discrete, variably sized, clear cytoplasmic vacuoles, which were stained with oil red O in frozen sections of formalin-fixed tissue.
authors.affiliation: Department of Infectious Diseases and Pathology, College of Veterinary Medicine, University of Florida, 2015 SW 16th Ave, Gainesville, FL 32608, USA. kondoh@ufl.edu
authors.forename: H
authors.initials: H
authors.lastname: Kondo
authors.forename: S C
authors.initials: SC
authors.lastname: Wickins
authors.forename: J A
authors.initials: JA
authors.lastname: Conway
authors.forename: M F
authors.initials: MF
authors.lastname: Mallicote
authors.forename: L C
authors.initials: LC
authors.lastname: Sanchez
authors.forename: D W
authors.initials: DW
authors.lastname: Agnew
authors.forename: L L
authors.initials: LL
authors.lastname: Farina
authors.forename: J R
authors.initials: JR
authors.lastname: Abbott
mesh_terms: D000818:Animals; D001391:Azo Compounds; D004396:Coloring Agents; D003937:Diagnosis, Differential; D037901:Euthanasia, Animal; D017809:Fatal Outcome; D005260:Female; D005629:Frozen Sections / Q000662:veterinary; D006734:Horse Diseases / Q000473:pathology*; D006736:Horses; D008080:Liposarcoma / Q000473:pathology / Q000662:veterinary*; D008479:Mediastinal Neoplasms / Q000473:pathology / Q000662:veterinary*; D008482:Mediastinum / Q000473:pathology
chemical_list: D001391:Azo Compounds; D004396:Coloring Agents; C011049:oil red O