title: Saphenous vein graft intervention: a review.
abstract: Saphenous vein grafts are prone to degeneration and occlusion. Vein graft disease continues to be a significant problem in maintaining long-term benefits after coronary artery bypass surgery. The neointimal hyperplasia and aggressive atherosclerosis that occur in saphenous vein grafts make interventions particularly challenging due to plaque embolization and the no-reflow phenomenon. This review discusses the pathophysiology of vein graft disease and the various percutaneous strategies that have been applied to manage vein grafts. We review the issues surrounding stent selection and various approaches to embolic protection devices. Finally, we discuss the technical steps that optimize success in treating this challenging patient subset.
authors.affiliation: Department of Cardiovascular Medicine, Hahnemann University Hospital, Philadelphia, PA 19102, USA.
authors.forename: Vindhya
authors.initials: V
authors.lastname: Hindnavis
authors.forename: Sung-Hae
authors.initials: SH
authors.lastname: Cho
authors.forename: Sheldon
authors.initials: S
authors.lastname: Goldberg
mesh_terms: D057505:Embolic Protection Devices; D017700:Embolism, Cholesterol / Q000628:therapy; D006083:Graft Occlusion, Vascular / Q000503:physiopathology / Q000628:therapy*; D006801:Humans; D019039:Platelet Glycoprotein GPIIb-IIIa Complex / Q000037:antagonists & inhibitors; D012501:Saphenous Vein / Q000637:transplantation*; D015607:Stents; D014665:Vasodilator Agents / Q000627:therapeutic use
chemical_list: D019039:Platelet Glycoprotein GPIIb-IIIa Complex; D014665:Vasodilator Agents