title: Peripheral painful traumatic trigeminal neuropathy: clinical features in 91 cases and proposal of novel diagnostic criteria.
abstract: OBJECTIVE
  To field-test carefully designed criteria for pain following trigeminal nerve trauma.
  
  
  METHODS
  In order to characterize the clinical phenotype, posttraumatic pain patients were studied and compared with classical trigeminal neuralgia patients (CTN, defined according to the International Headache Society's criteria). Based on etiology and features, trigeminal pain following trauma was defined as "peripheral painful traumatic trigeminal neuropathy" (PPTTN). Data were analyzed with t tests, ANOVA, chi-square, and regression analyses.
  
  
  RESULTS
  A total of 145 patients were included: 91 with PPTTN and 54 with CTN. Findings indicated that PPTTN criteria are clinically applicable in the detection and characterization of relevant cases. In contrast to accepted characteristics for PPTTN, the observed profile included both continuous and paroxysmal pain that was stabbing and/or burning. The quality, duration, and intensity were significantly different from the CTN patients (P < .05). PPTTN was consistently accompanied by trigeminal sensory abnormalities (96%) that were mostly allodynia, hyperor hypoalgesia, and only 1% of the PPTTN cases had anesthesia.
  
  
  CONCLUSIONS
  Overall, the proposed PPTTN criteria have proven to be clinically useful. In view of these results, modified PPTTN diagnostic criteria are proposed for use in future research.
authors.affiliation: Department of Oral Medicine, Hebrew University, Hadassah, Jerusalem, Israel. benoliel@cc.huji.ac.il
authors.forename: Rafael
authors.initials: R
authors.lastname: Benoliel
authors.forename: Yehuda
authors.initials: Y
authors.lastname: Zadik
authors.forename: Eli
authors.initials: E
authors.lastname: Eliav
authors.forename: Yair
authors.initials: Y
authors.lastname: Sharav
mesh_terms: D015331:Cohort Studies; D054893:Cone-Beam Computed Tomography; D003791:Dental Pulp Test; D003937:Diagnosis, Differential; D004244:Dizziness / Q000175:diagnosis; D004558:Electric Stimulation; D005157:Facial Pain / Q000175:diagnosis; D005260:Female; D006261:Headache / Q000175:diagnosis; D006801:Humans; D006930:Hyperalgesia / Q000175:diagnosis; D006941:Hyperesthesia / Q000175:diagnosis; D006987:Hypesthesia / Q000175:diagnosis; D008297:Male; D008340:Mandibular Nerve / Q000503:physiopathology; D008442:Maxillary Nerve / Q000293:injuries; D008875:Middle Aged; D009413:Nerve Fibers, Myelinated / Q000502:physiology; D036421:Nerve Fibers, Unmyelinated / Q000502:physiology; D009882:Ophthalmic Nerve / Q000293:injuries; D019647:Oral Surgical Procedures / Q000009:adverse effects; D010147:Pain Measurement; D017288:Pain Threshold / Q000502:physiology; D011446:Prospective Studies; D014110:Touch / Q000502:physiology; D061221:Trigeminal Nerve Injuries / Q000145:classification / Q000175:diagnosis*; D014277:Trigeminal Neuralgia / Q000175:diagnosis*