title: Central nervous system device infections.
abstract: Infections of central nervous system (CNS) devices are relatively common and potentially severe. The most common devices associated with infection are ventriculostomy catheters, shunts, and deep brain stimulators. The prevention, diagnosis, and management of these infections require a collaborative approach because of the complexity of surgery, the nuances of antimicrobial delivery in the CNS, and the potential for severe morbidity and mortality. This article focuses on new developments in the management and prevention of intracranial device infections, in particular ventriculostomy-related infections and infections of deep brain stimulators.
authors.affiliation: Division of Infectious Diseases, Emory University School of Medicine, 49 Jesse Hill Junior Drive, Atlanta, GA 30303, USA.
authors.forename: Edward
authors.initials: E
authors.lastname: Stenehjem
authors.forename: Wendy S
authors.initials: WS
authors.lastname: Armstrong
mesh_terms: D000890:Anti-Infective Agents / Q000627:therapeutic use; D001424:Bacterial Infections / Q000209:etiology* / Q000628:therapy; D055499:Catheter-Related Infections / Q000382:microbiology / Q000628:therapy; D002493:Central Nervous System Diseases / Q000209:etiology* / Q000628:therapy; D046690:Deep Brain Stimulation / Q000295:instrumentation; D006801:Humans; D009181:Mycoses / Q000209:etiology* / Q000628:therapy; D019736:Prostheses and Implants / Q000009:adverse effects* / Q000382:microbiology; D012307:Risk Factors; D014696:Ventriculostomy / Q000009:adverse effects*
chemical_list: D000890:Anti-Infective Agents