title: Trachomatous trichiasis and its management in endemic countries.
abstract: Trichiasis is the sight-threatening consequence of conjunctival scarring in trachoma, the most common infectious cause of blindness worldwide. Trachomatous trichiasis is the result of multiple infections from childhood with Chlamydia trachomatis, which causes recurrent chronic inflammation in the tarsal conjunctiva. This produces conjunctival scarring, entropion, trichiasis, and ultimately blinding corneal opacification. The disease causes painful, usually irreversible sight loss. Over eight million people have trachomatous trichiasis, mostly those living in poor rural communities in 57 endemic countries. The global cost is estimated at US$ 5.3 billion. The WHO recommends surgery as part of the SAFE strategy for controlling the disease.We examine the principles of clinical management, treatment options, and the challenging issues of providing the quantity and quality of surgery that is needed in resource-poor settings.
authors.affiliation: International Centre for Eye Health, London School of Hygiene and Tropical Medicine, London, UK. saul.rajak@lshtm.ac.uk
authors.forename: Saul N
authors.initials: SN
authors.lastname: Rajak
authors.forename: J Richard O
authors.initials: JR
authors.lastname: Collin
authors.forename: Matthew J
authors.initials: MJ
authors.lastname: Burton
mesh_terms: D002692:Chlamydia trachomatis / Q000472:pathogenicity*; D019353:Endemic Diseases; D014943:Global Health; D006801:Humans; D011203:Poverty; D017410:Practice Guidelines as Topic; D012424:Rural Population; D014141:Trachoma / Q000453:epidemiology / Q000382:microbiology / Q000601:surgery*; D058457:Trichiasis / Q000453:epidemiology / Q000382:microbiology / Q000601:surgery*; D014944:World Health Organization