title: PET imaging of tumor growth: not as easy as it looks.
abstract: Positron emission tomography can be used to image tumor proliferation when combined with appropriate labeled tracers, such as the thymidine analog [(18)F]-3'-deoxy-3'-fluorothymidine. Although thymidine kinase 1 is the principal mechanism of cell trapping, other variables, such as the cellular level of native thymidine, may need to be considered.
authors.affiliation: Karmanos Cancer Institute, Department of Oncology, Wayne State University, Detroit, Michigan 48201-2013, USA. ShieldsA@Karmanos.org
authors.forename: Anthony F
authors.initials: AF
authors.lastname: Shields
mesh_terms: D000818:Animals; D015224:Dideoxynucleosides; D006801:Humans; D009369:Neoplasms / Q000000981:diagnostic imaging*; D049268:Positron-Emission Tomography
chemical_list: D015224:Dideoxynucleosides; C002854:alovudine