title: Proposition of an outflow boundary approach for carotid artery stenosis CFD simulation.
abstract: The purpose of this study was to propose an innovative approach of setting outlet boundary conditions for the computational fluid dynamics (CFD) simulation of human common carotid arteries (CCAs) bifurcation based on the concept of energy loss minimisation at flow bifurcation. Comparisons between this new approach and previously reported boundary conditions were also made. The results showed that CFD simulation based on the proposed boundary conditions gave an accurate prediction of the critical stenosis ratio of carotid arteries (at around 65%). Other boundary conditions, such as the constant external pressure (P = 0) and constant outflow ratio, either overestimated or underestimated the critical stenosis ratio of carotid arteries. The patient-specific simulation results furthermore indicated that the calculated internal carotid artery flow ratio at CCA bifurcation (61%) coincided with the result obtained by clinical measurements through the use of Colour Doppler ultrasound.
authors.affiliation: Australian School of Advanced Medicine, Macquarie University, Sydney, 2109 NSW, Australia.
authors.forename: Yu
authors.initials: Y
authors.lastname: Zhang
authors.forename: Toyoki
authors.initials: T
authors.lastname: Furusawa
authors.forename: Sheau Fung
authors.initials: SF
authors.lastname: Sia
authors.forename: Mitsuo
authors.initials: M
authors.lastname: Umezu
authors.forename: Yi
authors.initials: Y
authors.lastname: Qian
mesh_terms: D001783:Blood Flow Velocity; D002343:Carotid Artery, Internal / Q000000981:diagnostic imaging* / Q000503:physiopathology; D016893:Carotid Stenosis / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D003198:Computer Simulation; D006801:Humans; D057446:Hydrodynamics; D008955:Models, Cardiovascular; D018615:Ultrasonography, Doppler, Color