title: Tetralogy of Fallot: anatomic variants and their impact on surgical management.
abstract: Tetralogy of Fallot is the most common form of cyanotic congenital heart disease. In this condition, episodic worsening of hypoxemia results from dynamic shifts in physiology, so-called "Tet spells." The relative frequency of this lesion and the risks of exacerbating "Tet spells" make anesthetic management of this patient population challenging. The conduct of palliative and reparative cardiac surgery is determined in large part by the anatomic variations within the spectrum of this disorder, most notably the severity of right ventricular outflow tract obstruction. This review will address the impact that the anatomic substrate has on the perioperative management of this interesting patient population.
authors.affiliation: Division of Pediatric Cardiology, Saint Louis University, St. Louis, MO 63104, USA. asharkey@slu.edu
authors.forename: Angela M
authors.initials: AM
authors.lastname: Sharkey
authors.forename: Anshuman
authors.initials: A
authors.lastname: Sharma
mesh_terms: D000758:Anesthesia / Q000379:methods*; D006348:Cardiac Surgical Procedures / Q000379:methods*; D006801:Humans; D000860:Hypoxia / Q000209:etiology; D019990:Perioperative Care / Q000379:methods; D012720:Severity of Illness Index; D013771:Tetralogy of Fallot / Q000453:epidemiology / Q000503:physiopathology* / Q000601:surgery; D014694:Ventricular Outflow Obstruction / Q000473:pathology / Q000601:surgery