title: Macrophage activation syndrome following Acinetobacter baumannii sepsis.
abstract: Macrophage activation syndrome (MAS) is a systemic disorder with a high mortality, commonly associated with rheumatological conditions, but which can also occur as a complication of several infections. Here we present a case of MAS following Acinetobacter baumannii sepsis. Early institution of therapy with prednisolone, cyclosporine, colistin, and polymyxin resulted in a prompt clinical recovery. There are very few reported cases of Acinetobacter-related MAS that have been successfully treated.
authors.affiliation: Department of Internal Medicine, Government Medical College, Kottayam, Kerala, 686008, India. teny007@gmail.com
authors.forename: Teny Mathew
authors.initials: TM
authors.lastname: John
authors.forename: Ceena N
authors.initials: CN
authors.lastname: Jacob
authors.forename: Cherian C
authors.initials: CC
authors.lastname: Ittycheria
authors.forename: Amrutha M
authors.initials: AM
authors.lastname: George
authors.forename: Amith G
authors.initials: AG
authors.lastname: Jacob
authors.forename: Saji
authors.initials: S
authors.lastname: Subramaniyam
authors.forename: Jabbar
authors.initials: J
authors.lastname: Puthiyaveettil
authors.forename: R
authors.initials: R
authors.lastname: Jayaprakash
mesh_terms: D000151:Acinetobacter Infections / Q000150:complications* / Q000188:drug therapy; D040981:Acinetobacter baumannii / Q000187:drug effects / Q000472:pathogenicity*; D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D003091:Colistin / Q000627:therapeutic use; D016572:Cyclosporine / Q000627:therapeutic use; D024901:Drug Resistance, Multiple, Bacterial; D006801:Humans; D055501:Macrophage Activation Syndrome / Q000150:complications / Q000382:microbiology*; D008297:Male; D011113:Polymyxins / Q000627:therapeutic use; D011239:Prednisolone / Q000627:therapeutic use; D018805:Sepsis / Q000150:complications* / Q000188:drug therapy / Q000382:microbiology
chemical_list: D000900:Anti-Bacterial Agents; D011113:Polymyxins; D016572:Cyclosporine; D011239:Prednisolone; D003091:Colistin