title: Percutaneous cement vertebroplasty in the treatment of symptomatic vertebral hemangiomas.
abstract: BACKGROUND
  Vertebral hemangiomas are benign tumors with a rich vasculature. Symptoms may vary from simple vertebral pain, sometimes resistant to conservative medical treatment, to progressive neurological deficit. Surgery or radiotherapy have been the treatment of choice for several years, but they were worsened by intraoperative and postoperative hemorrhagic complications related to the rich vascularization that characterize these kinds of lesions, often preceded by a preoperative embolization in the acute setting. Recently, a percutaneous, minimally invasive technique of vertebroplasty has been introduced into clinical practice as an alternative to traditional surgical and radiotherapy treatment of symptomatic vertebral hemangiomas with or without features of aggressiveness at imaging studies.
  
  
  OBJECTIVE
  This study aimed to illustrate the validity of treatment with percutaneous vertebroplasty (PVP) in patients with symptomatic vertebral hemangiomas (VHs).
  
  
  METHODS
  PVP in 26 patients with symptomatic VHs and its clinical effects were evaluated in 3-24 months follow-up.
  
  
  METHODS
  An inteventional pain management practice, a medical center, major metropolitan city, China.
  
  
  METHODS
  Twenty-six consecutive patients were treated with PVP; a total of 28 vertebral bodies. All patients were followed-up for 3-24 months, average 8.6 months. The clinical effects were evaluated with the visual analog scale (VAS) and 36-item short-form (SF-36) at preoperative and postoperative and final follow-up, comparing imaging before and post-treatment.
  
  
  RESULTS
  Twenty-six patients (28 vertebral bodies) were treated successfully with a satisfying resolution of painful symptoms within 24 to 72 hours. Cement distribution was always diffuse and homogeneous. We found paravertebral cement leakage in 3 cases without any onset of radicular symptoms related to epidural diffusion. Spinal canal and intervertebral foramen cement leakage wasn't noticed. No pulmonary embolism ever occurred and no clinical and symptomatic complications were observed. Hemangioma was confirmed by pathology examination. VAS scores decreased from 7.5 ± 1.5 preoperatively to 1.6 ± 0.6 postoperatively, with a final score of 0.7 ± 0.5. There was significant difference between postoperative and preoperative, and between final follow-up and preoperative (P < 0.05). At the postoperative and final follow-up, the SF-36 scores of patients was significantly higher than the preoperative in Role Physical, Bodily Pain, General Health, Vitality, Social Functioning, Role Emotional, and Mental Health (P < 0.05).
  
  
  CONCLUSIONS
  An observational study with a relatively small sample size.
  
  
  CONCLUSIONS
  PVP is an effective technique to treat symptomatic vertebral hemangioma, which is a valuable, minimally invasive, and quick method that allows a complete and lasting resolution of painful vertebral symptoms.
authors.affiliation: The First Affiliated Hospital, Chongqing Medical University, Chongqing, China.
authors.forename: Jie
authors.initials: J
authors.lastname: Hao
authors.forename: ZhenMing
authors.initials: Z
authors.lastname: Hu
mesh_terms: D000328:Adult; D000368:Aged; D001416:Back Pain / Q000601:surgery*; D001843:Bone Cements / Q000627:therapeutic use; D005260:Female; D005500:Follow-Up Studies; D006391:Hemangioma / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010147:Pain Measurement; D013125:Spinal Neoplasms / Q000601:surgery*; D013131:Spine / Q000601:surgery*; D016896:Treatment Outcome; D054854:Vertebroplasty / Q000379:methods*
chemical_list: D001843:Bone Cements