title: Valvular disease in patients requiring long-term left ventricular assist devices: pathophysiology and therapeutic options.
abstract: It is becoming clear that valvular pathology in patients requiring long-term mechanical ventricular support is an evolving, poorly understood and potentially dynamic problem. While strict guidelines are lacking, there is a growing experience in the understanding and management of the growing spectrum of valvular problems in this complex patient population. While the management of tricuspid and aortic regurgitation is of significant concern and may potentially have significant adverse impact on outcomes, other valvular pathologies can be problematic and require management in a manner unique to each patient.
authors.affiliation: Division of Cardiac Surgery, The Ohio State University Medical Center, Columbus, OH 43210, USA. michael.firstenberg@osumc.edu
authors.forename: Michael S
authors.initials: MS
authors.lastname: Firstenberg
authors.forename: Chittoor B
authors.initials: CB
authors.lastname: Sai-Sudhakar
authors.forename: Anelechi
authors.initials: A
authors.lastname: Anyanwu
mesh_terms: D001022:Aortic Valve Insufficiency / Q000503:physiopathology / Q000601:surgery; D006349:Heart Valve Diseases / Q000503:physiopathology / Q000601:surgery*; D006353:Heart-Assist Devices; D006801:Humans; D017410:Practice Guidelines as Topic; D013997:Time Factors; D016896:Treatment Outcome; D014262:Tricuspid Valve Insufficiency / Q000503:physiopathology / Q000601:surgery