title: (S)-ABOC: a rigid bicyclic β-amino acid as turn inducer.
abstract: In order to investigate the ability of the (S)-aminobicyclo[2.2.2]octane-2-carboxylic acid 1 (H-(S)-ABOC-OH) to induce reverse turns into peptides, two model tripeptides, in which this bicyclic unit was incorporated into the second position, were synthesized and analyzed by FT-IR, CD, NMR, and X-ray studies.
authors.affiliation: Institut des Biomolécules Max Mousseron UMR 5247 CNRS-UM1-UM2, Faculté de pharmacie, 15 Avenue Charles Flahault, 34093 Montpellier, France.
authors.forename: Christophe
authors.initials: C
authors.lastname: André
authors.forename: Baptiste
authors.initials: B
authors.lastname: Legrand
authors.forename: Cheng
authors.initials: C
authors.lastname: Deng
authors.forename: Claude
authors.initials: C
authors.lastname: Didierjean
authors.forename: Guillaume
authors.initials: G
authors.lastname: Pickaert
authors.forename: Jean
authors.initials: J
authors.lastname: Martinez
authors.forename: Marie Christine
authors.initials: MC
authors.lastname: Averlant-Petit
authors.forename: Muriel
authors.initials: M
authors.lastname: Amblard
authors.forename: Monique
authors.initials: M
authors.lastname: Calmes
mesh_terms: D000598:Amino Acids, Cyclic / Q000737:chemistry*; D008958:Models, Molecular; D008968:Molecular Conformation
chemical_list: C572030:(S)-aminobicyclo(2.2.2)octane-2-carboxylic acid; D000598:Amino Acids, Cyclic