title: Conus medullaris syndrome and acute colonic pseudoobstruction in a child with acute lymphoblastic leukemia.
abstract: A 5(3/12)-year-old boy with Philadelphia chromosome (+) pre-B acute lymphoblastic leukemia (ALL) without extramedullary involvement did not achieve remission after induction therapy. His family stopped therapy, but he was readmitted eight months later due to pyoderma, pneumonia and active leukemia with leukocytosis. During cytoreductive and antibiotic therapy, he developed progressive abdominal distension, pain, globe vesicale, tachypnea, and respiratory alkalosis. Bowel sounds could not be auscultated. Dilation, mainly in the large intestine, was detected radiologically. His neurological examination revealed absence of superficial reflexes and hypoesthesia along with normal motor strength and deep tendon reflexes in the lower extremities, consistent with conus medullaris syndrome, which was thought to give rise to acute colonic pseudo-obstruction.
authors.affiliation: Department of Pediatric Hematology, Dr. A.Y. Ankara Oncology Training and Research Hospital, Ankara, Turkey.
authors.forename: Zafer
authors.initials: Z
authors.lastname: Biçakçi
authors.forename: Arzu
authors.initials: A
authors.lastname: Akyay
authors.forename: Seda
authors.initials: S
authors.lastname: Oztürkmen
authors.forename: Asli
authors.initials: A
authors.lastname: Celebi-Tayfur
authors.forename: Sebahat
authors.initials: S
authors.lastname: Ağladioğlu
authors.forename: Nazan
authors.initials: N
authors.lastname: Ciledağ
authors.forename: Figen
authors.initials: F
authors.lastname: Ozçay
authors.forename: Kemal
authors.initials: K
authors.lastname: Arda
authors.forename: Lale
authors.initials: L
authors.lastname: Olcay
mesh_terms: D000208:Acute Disease; D002675:Child, Preschool; D003112:Colonic Pseudo-Obstruction / Q000000981:diagnostic imaging / Q000209:etiology* / Q000503:physiopathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications*; D011859:Radiography; D013117:Spinal Cord Compression / Q000209:etiology* / Q000503:physiopathology