title: How to use insulin-like growth factor 1 (IGF1).
abstract: Insulin-like growth factor 1 (IGF1) is produced in the liver and peripheral tissues including the growth plate, in response to growth hormone (GH) and is commonly used as a diagnostic marker of growth hormone deficiency (GHD) and to monitor GH replacement therapy, as recommended by an international GH consensus.1 However, while it is a useful biochemical tool, there are limitations to its use and results should be interpreted with care.
authors.affiliation: Department of Endocrinology, Great Ormond St Hospital, Great Ormond St, London, London WC1N 3JH, UK. peterc1@gosh.nhs.uk
authors.forename: Catherine J
authors.initials: CJ
authors.lastname: Peters
authors.forename: Mehul T
authors.initials: MT
authors.lastname: Dattani
mesh_terms: D006130:Growth Disorders / Q000097:blood / Q000175:diagnosis / Q000188:drug therapy*; D013006:Growth Hormone / Q000627:therapeutic use; D006801:Humans; D007334:Insulin-Like Growth Factor I / Q000032:analysis* / Q000627:therapeutic use*; D012016:Reference Values
chemical_list: D007334:Insulin-Like Growth Factor I; D013006:Growth Hormone