title: Scanning electron microscopic study of surface epithelial cells in erosive and nonerosive oral lichen planus.
abstract: OBJECTIVE
  Aim of the study is to study the surface epithelial cells of erosive, nonerosive lichen planus by scanning electron microscope (SEM) and to correlate it with that of normal mucosa and oral leukoplakia.
  
  
  METHODS
  Twenty biopsies of lichen planus and five biopsies of normal mucosa were taken. Half piece of each biopsy was processed for H&E stain and another half for SEM study.
  
  
  RESULTS
  Surface epithelial cells were showing different features.
  
  
  CONCLUSIONS
  Definite different features were seen in lichen planus-leukoplakia group than in normal oral mucosa. These changes are due to abnormality in cell maturation and differentiation.
  
  
  CONCLUSIONS
  SEM study is helpful in early detection of dysplasia. It can lead to early treatment of the lesion and thus prevention of squamous cell carcinoma.
authors.affiliation: Department of Oral Pathology and Microbiology SDKS Dental College and Hospital, Nagpur, Maharashtra, India. thakur.manjirimuk@gmail.com
authors.forename: Manjiri
authors.initials: M
authors.lastname: Thakur
authors.forename: Vinay
authors.initials: V
authors.lastname: Hazare
mesh_terms: D001706:Biopsy; D002462:Cell Membrane / Q000648:ultrastructure; D048430:Cell Shape; D048429:Cell Size; D004847:Epithelial Cells / Q000648:ultrastructure; D006801:Humans; D007365:Intercellular Junctions / Q000648:ultrastructure; D007972:Leukoplakia, Oral / Q000473:pathology / Q000648:ultrastructure; D017676:Lichen Planus, Oral / Q000473:pathology*; D008855:Microscopy, Electron, Scanning; D008871:Microvilli / Q000648:ultrastructure; D009061:Mouth Mucosa / Q000473:pathology* / Q000648:ultrastructure