title: Self-assembly of a confined rhodium catalyst for asymmetric hydroformylation of unfunctionalized internal alkenes.
abstract: A chiral supramolecular ligand has been assembled and applied to the rhodium-catalyzed asymmetric hydroformylation of unfunctionalized internal alkenes. Spatial confinement of the metal center within a chiral pocket results in reversed regioselectivity and remarkable enantioselectivities.
authors.affiliation: van't Hoff Institute for Molecular Sciences, University of Amsterdam, Science Park 904, 1098 XH, Amsterdam, The Netherlands.
authors.forename: Tendai
authors.initials: T
authors.lastname: Gadzikwa
authors.forename: Rosalba
authors.initials: R
authors.lastname: Bellini
authors.forename: Henk L
authors.initials: HL
authors.lastname: Dekker
authors.forename: Joost N H
authors.initials: JN
authors.lastname: Reek