title: New tricyclic alkaloids, cassiarins G, H, J, and K from leaves of Cassia siamea.
abstract: Four new alkaloids, cassiarins G, H, J, and K (1-4) which showed moderate antiplasmodial activity against Plasmodium falciparum 3D7, were isolated from the leaves of Cassia siamea (Leguminosae) and the structures of 1-4 were elucidated by 1D- and 2D-NMR analysis and X-ray crystallographic analysis.
authors.affiliation: Faculty of Pharmaceutical Sciences, Hoshi University, 2–4–41 Ebara, Shinagawa, Tokyo, Japan.
authors.forename: Jun
authors.initials: J
authors.lastname: Deguchi
authors.forename: Tomoe
authors.initials: T
authors.lastname: Hirahara
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Hirasawa
authors.forename: Wiwied
authors.initials: W
authors.lastname: Ekasari
authors.forename: Aty
authors.initials: A
authors.lastname: Widyawaruyanti
authors.forename: Osamu
authors.initials: O
authors.lastname: Shirota
authors.forename: Motoo
authors.initials: M
authors.lastname: Shiro
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Morita
mesh_terms: D000470:Alkaloids / Q000737:chemistry*; D000818:Animals; D000962:Antimalarials / Q000737:chemistry* / Q000494:pharmacology; D002366:Cassia / Q000737:chemistry*; D018360:Crystallography, X-Ray; D006575:Heterocyclic Compounds, 3-Ring / Q000737:chemistry* / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D018515:Plant Leaves / Q000737:chemistry*; D010963:Plasmodium falciparum / Q000187:drug effects
chemical_list: D000470:Alkaloids; D000962:Antimalarials; D006575:Heterocyclic Compounds, 3-Ring