title: Tetralogy of Fallot: perioperative anesthetic management of children and adults.
abstract: Tetralogy of Fallot (TOF) is a common congenital heart defect in children. Perioperative considerations include preoperative preparation for surgery, intraoperative anesthetic management, and common postoperative issues in the intensive care unit. Surgical debates have shifted away from 2-stage versus single-stage repairs to debates of how surgery to limit pulmonary insufficiency (PI) may have significant long-term impact as the child grows. There are many adult survivors of TOF repair in infancy who now present with a unique set of problems related to PI and right ventricular dysfunction. These adults provide new insights into congenital heart disease (CHD) and how management strategies early in life may have significant implications much later in life. Patients with complex CHD should have lifelong follow-up, so our knowledge will continue to improve, and the best possible care can be provided for these patients.
authors.affiliation: Children's Hospital Colorado and University of Colorado, Denver, CO, USA. Mark.Twite@UCDenver.edu
authors.forename: Mark D
authors.initials: MD
authors.lastname: Twite
authors.forename: Richard J
authors.initials: RJ
authors.lastname: Ing
mesh_terms: D000328:Adult; D000367:Age Factors; D000758:Anesthesia / Q000379:methods*; D000777:Anesthetics / Q000008:administration & dosage; D006348:Cardiac Surgical Procedures / Q000379:methods*; D002648:Child; D006330:Heart Defects, Congenital / Q000503:physiopathology / Q000601:surgery; D006801:Humans; D019990:Perioperative Care / Q000379:methods; D017741:Survivors; D013771:Tetralogy of Fallot / Q000503:physiopathology / Q000601:surgery*; D018497:Ventricular Dysfunction, Right / Q000209:etiology / Q000503:physiopathology
chemical_list: D000777:Anesthetics