title: BioSMACK: a linux live CD for genome-wide association analyses.
abstract: Recent advances in high-throughput genotyping technologies have enabled us to conduct a genome-wide association study (GWAS) on a large cohort. However, analyzing millions of single nucleotide polymorphisms (SNPs) is still a difficult task for researchers conducting a GWAS. Several difficulties such as compatibilities and dependencies are often encountered by researchers using analytical tools, during the installation of software. This is a huge obstacle to any research institute without computing facilities and specialists. Therefore, a proper research environment is an urgent need for researchers working on GWAS. We developed BioSMACK to provide a research environment for GWAS that requires no configuration and is easy to use. BioSMACK is based on the Ubuntu Live CD that offers a complete Linux-based operating system environment without installation. Moreover, we provide users with a GWAS manual consisting of a series of guidelines for GWAS and useful examples. BioSMACK is freely available at http://ksnp.cdc. go.kr/biosmack.
authors.affiliation: Division of Structural and Functional Genomics, Center for Genome Science, National Institute of Health, Chungcheongbuk-do, Korea.
authors.forename: Chang Bum
authors.initials: CB
authors.lastname: Hong
authors.forename: Young Jin
authors.initials: YJ
authors.lastname: Kim
authors.forename: Sanghoon
authors.initials: S
authors.lastname: Moon
authors.forename: Young-Ah
authors.initials: YA
authors.lastname: Shin
authors.forename: Min Jin
authors.initials: MJ
authors.lastname: Go
authors.forename: Dong-Joon
authors.initials: DJ
authors.lastname: Kim
authors.forename: Jong-Young
authors.initials: JY
authors.lastname: Lee
authors.forename: Yoon Shin
authors.initials: YS
authors.lastname: Cho
mesh_terms: D055106:Genome-Wide Association Study / Q000379:methods*; D012984:Software