title: Iodobenzene diacetate (IBD) catalyzed an quick oxidative aromatization of Hantzsch-1,4-dihydropyridines to pyridines under ultrasonic irradiation.
abstract: This project was undertaken to demonstrate the potential of iodobenzene diacetate for the oxidative aromatization of Hantzch-1,4-dihydropyridines under ultrasonic irradiation. All reactions were carried out under ultrasonic irradiation and results were compared with traditional method. Sonochemical switching was observed in case of oxidative aromatization of 4-n-alkyl substituted 1,4-DHP. Without sonication, dealkylation occurred in case of n-alkyl substituted 1,4-DHP (ionic mechanism) but under ultrasonic irradiation, n-alkyl group was not expelled (radical mechanism). However, secondary alkyl (isopropyl) and benzyl group were expelled under both conditions.
authors.affiliation: Department of Chemistry, Kururkshetra University, Kurukshetra, Haryana 136119, India. drpkawasthignkc@rediffmail.com
authors.forename: Parvin
authors.initials: P
authors.lastname: Kumar
authors.forename: Ashwani
authors.initials: A
authors.lastname: Kumar
authors.forename: Khalid
authors.initials: K
authors.lastname: Hussain
mesh_terms: D000085:Acetates / Q000737:chemistry*; D002384:Catalysis; D007462:Iodobenzenes / Q000737:chemistry*; D015394:Molecular Structure; D010084:Oxidation-Reduction; D011725:Pyridines / Q000138:chemical synthesis* / Q000737:chemistry; D013010:Sonication
chemical_list: D000085:Acetates; D007462:Iodobenzenes; D011725:Pyridines