title: Bronchiolitis obliterans organizing pneumonia due to titanium nanoparticles in paint.
abstract: We present a case of a 58-year-old man who experienced Bronchiolitis obliterans organizing pneumonia after a 3-month exposure to polyester powder paint. Mineralogical analysis by transmission electron microscopy of a pulmonary sample and the polyester powder paint he was exposed to showed the presence of titanium dioxide nanoparticles in both. We suggest that exposure to titanium dioxide nanoparticles should be added to the etiology of Bronchiolitis obliterans organizing pneumonia.
authors.affiliation: Department of Internal Medicine, Taoyuan Armed Forces General Hospital, Taoyuan, Taiwan.
authors.forename: Tong-Hong
authors.initials: TH
authors.lastname: Cheng
authors.forename: Fu-Chang
authors.initials: FC
authors.lastname: Ko
authors.forename: Junn-Liang
authors.initials: JL
authors.lastname: Chang
authors.forename: Kuo-An
authors.initials: KA
authors.lastname: Wu
mesh_terms: D000890:Anti-Infective Agents / Q000627:therapeutic use; D015897:Comorbidity; D018549:Cryptogenic Organizing Pneumonia / Q000139:chemically induced* / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology; D057210:Delayed Diagnosis; D017809:Fatal Outcome; D006801:Humans; D008168:Lung / Q000737:chemistry; D008297:Male; D008775:Methylprednisolone / Q000627:therapeutic use; D008875:Middle Aged; D053758:Nanoparticles / Q000009:adverse effects* / Q000032:analysis; D009784:Occupational Diseases / Q000139:chemically induced* / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology; D010150:Paint / Q000009:adverse effects*; D010316:Particle Size; D011014:Pneumonia / Q000175:diagnosis; D011091:Polyesters; D011208:Powders; D018805:Sepsis / Q000209:etiology; D020775:Thoracic Surgery, Video-Assisted; D014025:Titanium / Q000009:adverse effects* / Q000032:analysis
chemical_list: D000890:Anti-Infective Agents; D011091:Polyesters; D011208:Powders; C009495:titanium dioxide; D014025:Titanium; D008775:Methylprednisolone