title: Endoscopic coagulation of choroid plexus hyperplasia.
abstract: Hydrocephalus is a clinical disorder resulting from an imbalance between the production of CSF and its resorption, of which the latter is mostly a disadvantage. In rare cases of choroid plexus papilloma or carcinoma, hydrocephalus is due to an overproduction of CSF. Choroid plexus hyperplasia (CPH) is a distinct clinicopathological entity in which the enlarged choroid plexus produces large amounts of CSF. Historically, patients with CPH were treated by shunt procedures or by microsurgical removal of the choroid plexus, which is associated with a high complication rate. In this paper the authors show that endoscopic plexus coagulation can result in restoring the equilibrium of the intracranial fluid volumes, resulting in shunt independency. In this way, both the shunt-related complications and the bleeding risks of microsurgical plexectomy are avoided. In instances of hydrocephalus, thorough efforts should be made to demonstrate the underlying pathophysiology to choose the optimal treatment, of which shunt procedures should receive the least priority.
authors.affiliation: Department of Neurosurgery, Ghent University Hospital, Ghent, Belgium. giorgiohallaert@yahoo.com
authors.forename: Giorgio G
authors.initials: GG
authors.lastname: Hallaert
authors.forename: Dimitri J
authors.initials: DJ
authors.lastname: Vanhauwaert
authors.forename: Karl
authors.initials: K
authors.lastname: Logghe
authors.forename: Caroline
authors.initials: C
authors.lastname: Van den Broecke
authors.forename: Edward
authors.initials: E
authors.lastname: Baert
authors.forename: Dirk
authors.initials: D
authors.lastname: Van Roost
authors.forename: Jacques
authors.initials: J
authors.lastname: Caemaert
mesh_terms: D020314:Central Nervous System Fungal Infections / Q000150:complications / Q000601:surgery; D002552:Cerebral Ventricles / Q000473:pathology; D002557:Cerebrospinal Fluid Shunts; D002675:Child, Preschool; D002831:Choroid Plexus / Q000473:pathology* / Q000601:surgery*; D004322:Drainage; D004564:Electrocoagulation; D004724:Endoscopy / Q000379:methods*; D005260:Female; D006801:Humans; D006849:Hydrocephalus / Q000150:complications / Q000601:surgery; D006965:Hyperplasia / Q000134:cerebrospinal fluid / Q000601:surgery*; D007010:Hyponatremia / Q000209:etiology; D008279:Magnetic Resonance Imaging; D020127:Recovery of Function; D012086:Reoperation; D016683:Supine Position; D016896:Treatment Outcome