title: Mitochondrial DNA control region variation in an autochthonous Basque population sample from the Basque Country.
abstract: Mitochondrial control region (16024-576) sequences were generated from 106 samples from autochthonous Basques from the Autonomous Community of the Basque Country. It is especially important to generate mtDNA databases from isolated populations in order to maximize the power of discrimination of this molecular marker. It also represents a useful approach to carry out a more accurate haplogroup classification. This is the first database report of complete control region sequences in an autochthonous Basque population sample. Strict selection criteria of autochthonous individuals, automation of laboratory processing and independent reviews of the raw electropherograms ensure the high quality of these sequences and their utility as reference population data of the autochthonous Basque population.
authors.affiliation: BIOMICs Research Group, Centro de Investigación y Estudios Avanzados Lucio Lascaray, Universidad del País Vasco UPV/EHU, Avda. Miguel de Unamuno 3, 01006 Vitoria-Gasteiz, Spain.
authors.forename: Sergio
authors.initials: S
authors.lastname: Cardoso
authors.forename: María Jesús
authors.initials: MJ
authors.lastname: Villanueva-Millán
authors.forename: Laura
authors.initials: L
authors.lastname: Valverde
authors.forename: Adrian
authors.initials: A
authors.lastname: Odriozola
authors.forename: Jose M
authors.initials: JM
authors.lastname: Aznar
authors.forename: Sergio
authors.initials: S
authors.lastname: Piñeiro-Hermida
authors.forename: Marian M
authors.initials: MM
authors.lastname: de Pancorbo
mesh_terms: D016172:DNA Fingerprinting; D004272:DNA, Mitochondrial / Q000235:genetics*; D005006:Ethnicity / Q000235:genetics*; D014644:Genetic Variation; D005828:Genetics, Population; D006239:Haplotypes; D006801:Humans; D016133:Polymerase Chain Reaction; D017422:Sequence Analysis, DNA; D013030:Spain
chemical_list: D004272:DNA, Mitochondrial