title: Hepatitis B and C viral infections among blood donors from rural Ghana.
abstract: OBJECTIVE
  To investigate the prevalence of Hepatitis B and C infections and co-infections among blood donors in a rural community of Ghana.
  
  
  METHODS
  A retrospective study.
  
  
  METHODS
  Samples of blood donated between January 2007 and December 2008 were screen for Hepatitis B and C viruses at the Agogo Presbyterian Hospital.
  
  
  RESULTS
  The prevalence of Hepatitis B viral (HBV) infection was highest in females 21.4% (95% CI: 11.6-34.4) in 2006 than males in the same year 13.2% (95% CI: 10.8-15.9). Hepatitis C viral (HCV) infection was highest among males at 11.6% (95% CI: 9.5-13.8) in 2007. HBV and HCV co-infection was higher in males 2.6% (95% CI: 1.6-3.8) than females 1.3% (95% CI: 0-7.0) in 2007. The overall prevalence of HBV and HCV was 13.8% (95% CI: 11.4-16.4) and 9.4% (95% CI: 7.4-11.6) respectively in 2006. The rate of co-infection of HBV and HCV however increased from 1.6% (95% CI: 0.8-2.7) in 2006 to 2.2% (95% CI: 1.3-3.2) in 2008 in males and from 0% (95% CI: 0-6.4) in 2006 to 1.2% (95% CI: 0-6.5) in 2008 in females.
  
  
  CONCLUSIONS
  The single infections of HBV and HCV reduced but co-infection of these transfusion transmitted infections (TTI) increased. Measures such as more sensitive techniques and education must be employed in these areas.
authors.affiliation: Kumasi Centre for Collaborative Research in Tropical Medicine, Kumasi, Ghana. nkrumah@kccr.de
authors.forename: B
authors.initials: B
authors.lastname: Nkrumah
authors.forename: M
authors.initials: M
authors.lastname: Owusu
authors.forename: H O
authors.initials: HO
authors.lastname: Frempong
authors.forename: P
authors.initials: P
authors.lastname: Averu
mesh_terms: D000293:Adolescent; D000328:Adult; D001782:Blood Donors; D060085:Coinfection / Q000453:epidemiology; D005260:Female; D005869:Ghana / Q000453:epidemiology; D006509:Hepatitis B / Q000453:epidemiology*; D006526:Hepatitis C / Q000453:epidemiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012189:Retrospective Studies; D012423:Rural Health / Q000706:statistics & numerical data*; D017678:Sex Distribution; D055815:Young Adult