title: Congenital anophthalmia and microphthalmia: epidemiology and orbitofacial rehabilitation.
abstract: OBJECTIVE
  To describe the prevalence of congenital anophthalmia and microphthalmia in Hospital Universitario La Paz, and to identify associated risk factors and evaluate cosmetic results in treated and nontreated patients.
  
  
  METHODS
  A retrospective, descriptive, cross-sectional study of patients treated with orbital expanding techniques (cases) and nontreated patients (controls) was carried out as a comparative case series study. A total of 36 patients with unilateral or bilateral anophthalmia or microphthalmia as main diagnosis were included; 52 epidemiological and management variables for each patient were analyzed. The study evaluated orbital growth and facial symmetry.
  
  
  RESULTS
  The overall cosmetic result in the study's group of patients was satisfactory: 66.7% showed good or very good orbital growth, and 75% showed good or very good facial symmetry. Controls had better cosmetic outcome but showed more cataracts (P = 0.05), inferior colobomas (P = 0.026), and family history (P = 0.056) than the cases. Controls also showed significantly better orbital growth (P = 0.042) and facial symmetry (P = 0.014) than the cases.
  
  
  CONCLUSIONS
  This study suggests that the mere presence of a globe (controls) still provides better orbitofacial development than the artificial stimulation (cases) currently available for patients with congenital anophthalmia and microphthalmia, who receive internal and external orbital rehabilitation.
authors.affiliation: Ophthalmology Service of Hospital de Torrejón, Madrid, Spain. sarallog@gmail.com
authors.forename: Sara
authors.initials: S
authors.lastname: Llorente-González
authors.forename: J
authors.initials: J
authors.lastname: Peralta-Calvo
authors.forename: J M
authors.initials: JM
authors.lastname: Abelairas-Gómez