title: Good results after repeated resection for colorectal liver metastases.
abstract: BACKGROUND
  Our study aim was to evaluate the perioperative events, postoperative events and survival after a second liver resection due to colorectal liver metastases (CLM), compared with a matched control group that had only undergone primary liver resection due to CLM.
  
  
  METHODS
  Retrospective review of charts from patients having undergone a second liver resection due to CLM. A control group was identified by selecting the first liver resection due to CLM occurring after a second resection due to CLM. Twenty-four patients were hereby included in both the primary resection group (PRG) and the second resection group (SRG). The groups were compared statistically with regard to demographics, primary tumour and hepatic involvement.
  
  
  RESULTS
  No significant differences between the groups were noted in terms of perioperative events, although there was a trend towards PRG resections involving more liver segments than SRG resections (p = 0.08). The rate of postoperative surgical complications was 17.4% in the PRG and 4% in the SRG (p = 0.18). The admission time was 10.6 days in the PRG and 8.4 days in the SRG (p = 0.71). 30-day mortality was 4% in the PRG and 0% in the SRG (p = 0.41). The five-year survival was 36% in the PRG and 42% in the SRG (p = 0.17)
  
  
  CONCLUSIONS
  This study shows that a second hepatic resection due to recurrent CLM is safe and feasible. It also shows that patients undergoing a second liver resection due to CLM have five-year survival rates comparable to those of patients who have only undergone one hepatic resection due to CLM.
  
  
  BACKGROUND
  Not relevant.
  
  
  BACKGROUND
  Not relevant.
authors.affiliation: Abdominalcentret, Klinik for Kirurgisk Gastroenterologi Og Transplantation CTx, Rigshospitalet, 2100 Copenhagen, Denmark. hc.rolff@gmail.com
authors.forename: Hans Christian
authors.initials: HC
authors.lastname: Rolff
authors.forename: Dan
authors.initials: D
authors.lastname: Calatayud
authors.forename: Peter Nørgaard
authors.initials: PN
authors.lastname: Larsen
authors.forename: André
authors.initials: A
authors.lastname: Wettergren
mesh_terms: D000368:Aged; D015179:Colorectal Neoplasms / Q000473:pathology*; D005260:Female; D006498:Hepatectomy; D006801:Humans; D008113:Liver Neoplasms / Q000401:mortality / Q000556:secondary* / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000601:surgery*; D011183:Postoperative Complications; D015996:Survival Rate