title: Conformational stability of collagen triple helices functionalized in the Yaa position by click chemistry.
abstract: Click chemistry was used to introduce moieties as sterically demanding as monosaccharides into the Yaa position of collagen model peptides. The effect of different triazolyl derivatives as well as the configuration of the functionalized proline residue on the thermal stability of the collagen triple helices was examined.
authors.affiliation: Department of Chemistry, University of Basel, St. Johanns-Ring 19, 4056 Basel, Switzerland.
authors.forename: Roman S
authors.initials: RS
authors.lastname: Erdmann
authors.forename: Helma
authors.initials: H
authors.lastname: Wennemers
mesh_terms: D057930:Click Chemistry / Q000379:methods; D003094:Collagen / Q000737:chemistry*; D010455:Peptides / Q000737:chemistry*; D055550:Protein Stability; D017433:Protein Structure, Secondary; D013696:Temperature; D014230:Triazoles / Q000737:chemistry*
chemical_list: D010455:Peptides; D014230:Triazoles; D003094:Collagen