title: Divergent outcomes of gold(I)-catalyzed indole additions to 3,3-disubstituted cyclopropenes.
abstract: Depending on the conditions employed, gold(I)-catalyzed addition of indoles to 3,3-disubstituted cyclopropenes can be controlled to yield either 3-(E)-vinylindoles (3) or bis-indolylalkanes (4). If the cyclopropene substituents are sterically bulky, unprecedented gold-catalyzed oxidation under air occurs to yield bis-indolylalkene (5) and epoxide (6) at room temperature.
authors.affiliation: School of Engineering and Physical Sciences, Heriot-Watt University, Edinburgh EH14 4AS, Scotland, United Kingdom.
authors.forename: Paul C
authors.initials: PC
authors.lastname: Young
authors.forename: Maximillian S
authors.initials: MS
authors.lastname: Hadfield
authors.forename: Lynn
authors.initials: L
authors.lastname: Arrowsmith
authors.forename: Kristina M
authors.initials: KM
authors.lastname: Macleod
authors.forename: Richard J
authors.initials: RJ
authors.lastname: Mudd
authors.forename: James A
authors.initials: JA
authors.lastname: Jordan-Hore
authors.forename: Ai-Lan
authors.initials: AL
authors.lastname: Lee
mesh_terms: D002384:Catalysis; D003521:Cyclopropanes / Q000737:chemistry*; D006046:Gold / Q000737:chemistry*; D007211:Indoles / Q000737:chemistry*; D015394:Molecular Structure; D010084:Oxidation-Reduction
chemical_list: D003521:Cyclopropanes; D007211:Indoles; D006046:Gold; C021985:cyclopropene