title: [Evaluation of the post-effect of acupuncture at Sanyinjiao (SP 6) under sleep deprivation by resting-state amplitude of low-frequency fluctuation: a fMRI study].
abstract: OBJECTIVE
  To discuss the central modulating mechanism of Sanyinjiao (SP 6) and the amplitude of low-frequency fluctuation (ALFF) differences of the functional brain regions between SP 6 and sham acupoint.
  
  
  METHODS
  Sixteen volunteers accepted right Sanyinjiao (SP 6) (SP 6 group) or right sham (sham group) acupuncture for two times after 24 h sleep deprivation (SD), there was two weeks between two acupunctures. The needle was retained for 4 minutes and the brain fMRI scanning was performed by 3.0 TMR every time. The ALFF consequent data was processed by REST. One-sample t-test and two-pair t-test were performed by SPM5.
  
  
  RESULTS
  SP 6 group mainly caused ALFF change in inferior parietal lobule, posterior cingulated while sham group in precuneus, posterior cingulated. SP 6 group increased ALFF in left fusiform temporal gyrus, medial frontal gyrus with no decreased regions compared with sham group.
  
  
  CONCLUSIONS
  Retaining needle dose influence the activity of the brain region during resting-state in both group, especially the mood-related regions. And its mechanism is probably that the relevant effect is carried out by regulating function to target organs of complex brain network comprised of relevant functional center and related brain region. There are differences between SP 6 and Sham acupoint.
authors.affiliation: Department of Radiation, The First Affiliated Hospital, Nanchang University, Nanchang 330006, Jiangxi, China.
authors.forename: Xi-Jian
authors.initials: XJ
authors.lastname: Dai
authors.forename: You-Jiang
authors.initials: YJ
authors.lastname: Min
authors.forename: Hong-Han
authors.initials: HH
authors.lastname: Gong
authors.forename: Lei
authors.initials: L
authors.lastname: Gao
authors.forename: Si-Yong
authors.initials: SY
authors.lastname: Wang
authors.forename: Fu-Qing
authors.initials: FQ
authors.lastname: Zhou
authors.forename: Xiang-Zuo
authors.initials: XZ
authors.lastname: Xiao
authors.forename: Bi-Xia
authors.initials: BX
authors.lastname: Liu
mesh_terms: D015669:Acupuncture Points; D015670:Acupuncture Therapy; D001921:Brain / Q000000981:diagnostic imaging / Q000503:physiopathology; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D011859:Radiography; D012892:Sleep Deprivation / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000628:therapy*; D055815:Young Adult