title: Electrochemical cleavage of sulfonamides: an efficient and tunable strategy to prevent β-fragmentation and epimerization.
abstract: The electrochemical reduction of sensitive sulfonamides is described. The addition of a benzoyl group on the nitrogen atom facilitates the reductive cleavage of sulfonamides preventing β-fragmentation and epimerization. This strategy was successfully applied to the cyclopropylamine and to α-amino stannanes.
authors.affiliation: Université de Nantes, CNRS, Chimie Et Interdisciplinarité: Synthèse, Analyse et Modélisation (CEISAM), UMR CNRS 6230, Faculté des Sciences et des Techniques, 2, rue de la Houssinière, BP 92208, 44322 Nantes Cedex 3, France.
authors.forename: Pierre
authors.initials: P
authors.lastname: Viaud
authors.forename: Vincent
authors.initials: V
authors.lastname: Coeffard
authors.forename: Christine
authors.initials: C
authors.lastname: Thobie-Gautier
authors.forename: Isabelle
authors.initials: I
authors.lastname: Beaudet
authors.forename: Nicolas
authors.initials: N
authors.lastname: Galland
authors.forename: Jean-Paul
authors.initials: JP
authors.lastname: Quintard
authors.forename: Erwan
authors.initials: E
authors.lastname: Le Grognec