title: t(6;9)(p23;q34) presenting acute myeloid leukemia in a child with an unsuspected 45,X/46,X,derY [?t(Yp;Yq)] chromosomal constitution: yet another Y chromosome overdosage and malignancy association.
abstract: Development of leukemia in patients with sexual chromosome abnormalities is relatively rare and mostly involves cases of monosomy X, Turner syndrome. Here, we report on a child having a 45,X/46,X,derY [?t(Yp;Yq)] chromosomal constitution (variant Turner syndrome) presenting with concordant acute myeloid leukemia and a rarely seen clonal neoplasic cell lineage-related karyotype, t(6;9)(p23;q34).
authors.affiliation: Department of Pediatric Genetics, Ondokuz Mayis University Medical Faculty, Samsun, Turkey. ogurg@yahoo.com
authors.forename: Gönül
authors.initials: G
authors.lastname: Ogur
authors.forename: Feride
authors.initials: F
authors.lastname: Duru
authors.forename: Emel
authors.initials: E
authors.lastname: Ozyurek
authors.forename: Tunc
authors.initials: T
authors.lastname: Fisgin
mesh_terms: D002648:Child; D002869:Chromosome Aberrations; D002896:Chromosomes, Human, Pair 6 / Q000235:genetics*; D002899:Chromosomes, Human, Pair 9 / Q000235:genetics*; D041322:Chromosomes, Human, Y / Q000235:genetics*; D005260:Female; D006801:Humans; D007621:Karyotyping; D015470:Leukemia, Myeloid, Acute / Q000235:genetics*; D011379:Prognosis; D014178:Translocation, Genetic / Q000235:genetics*; D014424:Turner Syndrome / Q000235:genetics*