title: [Evaluation of the risk of the clinical-surgical and pathology study findings in newborns with necrotizing enterocolitis who have received surgical treatment].
abstract: BACKGROUND
  Despite advances in neonatal care between 20% and 63% of children with necrotizing enterocolitis (NEC) require surgery. The aim was correlation the risk factors of infants with NEC "IIB / IIIA / IIIB" Bell and the clinical, surgical and pathological findings.
  
  
  METHODS
  In the children with diagnosis of NEC surgically treated, were analyzed of variables: clinical, surgical and pathological findings. We studied two groups: control (n=5) and NEC group (n=12). Comparisons were made between groups using the Mann-Whitney U- and the Spearman coefficient (r). To assess the risk of morbidity / mortality associated with the extent of intestinal resection we applied the Cox regression.
  
  
  RESULTS
  We found differences (p < 0.05) between control group and the NEC group regarding Bell, the mean height of villi, Chiu and the number of goblet cells. In the NEC group we find correlations (p < 0.05) from Bell, regarding Chiu (r = 0.761), resection of the colon (r = 0.687), pneumatosis / perforation (r = 1) and the mean height of villi (r = -0.878). The gut reseccion was at 26 cm (3-107). We observed a risk of 1.04 in the neonatal period (p > 0.05) of mortality or consequence post-enterocolitis associated with the extent of bowel resection.
  
  
  CONCLUSIONS
  The decrease in the average height of villi, the highest level of microscopic intestinal injury and reduced goblet cell population contributes to a greater extent of intestinal resection, which favors the risk of death or developing consequence post-enterocolitis.
authors.affiliation: Servicio de Cirugía Pediátrica, Hospital Pediátrico Baca Ortiz, Ecuador. fcaceres@hsjdbcn.org
authors.forename: F
authors.initials: F
authors.lastname: Cáceres
authors.forename: D
authors.initials: D
authors.lastname: Franco
authors.forename: J
authors.initials: J
authors.lastname: Arboleda
authors.forename: P
authors.initials: P
authors.lastname: Cuesta
authors.forename: E
authors.initials: E
authors.lastname: Hidalgo
authors.forename: P
authors.initials: P
authors.lastname: Astudillo
mesh_terms: D020345:Enterocolitis, Necrotizing / Q000473:pathology* / Q000601:surgery*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D018570:Risk Assessment