title: Carotid IMT in type 2 diabetic patients: a survey on factors of influence.
abstract: The study was aimed to determine factors of carotid intimamedia thickness (CIMT) in a population of patients with type 2 diabetes (T2D). A survey was conducted on 370 patients (mean age 60.3±8.3 years and diabetes duration 8.6±6.2 years) with T2D and coronary artery disease. Multivariate linear regression analysis was built to define the factors of CIMT, when age, systolic and diastolic blood pressure, weight, body mass index, waist circumference, glycaemia, urea, creatinin, triglycerides, total cholesterol, LDL-, HDL-, and non-HDL-cholesterol were put in a model. Mean CIMT of 0.8992±0.1529 mm, and its maximal value of 0.9905±1.946 mm was detected in this study population. Regression analysis demonstrated that mean and maximal CIMT were independently influenced by age, blood creatinin, diastolic pressure and non-HDL cholesterol, as well. The results have clinical value in defining target groups in patients with T2D and arterial hypertension, higher non-HDL cholesterol and blood creatinin, and those-that are older have a greater probability of detection of increased CIMT.
authors.affiliation: Faculty of Medicine, University Cardiology Clinic, Skopje, R. Macedonia.
authors.forename: M
authors.initials: M
authors.lastname: Bosevski
authors.forename: Ljubica
authors.initials: L
authors.lastname: Georgievska-Ismail
authors.forename: Slavco
authors.initials: S
authors.lastname: Tosev
mesh_terms: D017668:Age of Onset; D000368:Aged; D001786:Blood Glucose / Q000032:analysis; D001794:Blood Pressure; D015992:Body Mass Index; D059168:Carotid Intima-Media Thickness / Q000706:statistics & numerical data*; D008078:Cholesterol, LDL / Q000097:blood*; D003324:Coronary Artery Disease / Q000453:epidemiology*; D003404:Creatinine / Q000097:blood*; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000175:diagnosis / Q000453:epidemiology / Q000503:physiopathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D018570:Risk Assessment; D012307:Risk Factors; D014280:Triglycerides / Q000097:blood
chemical_list: D001786:Blood Glucose; D008078:Cholesterol, LDL; D014280:Triglycerides; D003404:Creatinine