title: [Acute encephalopathy associated with the use of intravenous immunoglobulin. Report of one case].
abstract: Adverse reactions to intravenous immunoglobulin (ivIg) therapy, such as anaphylaxis, acute encephalopathy, aseptic meningitis, or thrombotic phenomena are uncommon. We report a 58-year-old man with hypertension presenting with muscle weakness which led to paraparesia and respiratory failure. With the diagnosis of Guillain-Barré syndrome (GBS), he was treated with ivIg. He developed an acute encephalopathy few hours after the administration of ivIg, with a decreased level of consciousness and agitation. A CT scan revealed moderate and diffuse brain edema. Encephalopathy resolved 96 hours after ivIg withdrawal and use of plasma exchange. A CT scan performed seven days after showed the resolution of brain edema.
authors.affiliation: Departamento de Ciencias Neurológicas Oriente, Facultad de Medicina, Universidad de Chile, Santiago, Chile.
authors.forename: Alvaro
authors.initials: A
authors.lastname: Soto V
authors.forename: Luis
authors.initials: L
authors.lastname: Cartier R
mesh_terms: D001929:Brain Edema / Q000139:chemically induced / Q000473:pathology* / Q000628:therapy; D020275:Guillain-Barre Syndrome / Q000188:drug therapy*; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D010951:Plasma Exchange
chemical_list: D016756:Immunoglobulins, Intravenous