title: Active methylene-based multicomponent reactions under microwave heating.
abstract: The use of emerging multicomponent reactions (MCRs) in conjunction with microwave (MW)-assisted chemistry techniques is dramatically reducing chemical waste and reaction times in several organic syntheses and chemical transformations. MW-assisted active methylene-based multicomponent  reactions serve as a rapid and efficient tool for the synthesis of versatile heterocycles, particularly those containing structural diversity and complexity via a one-pot operation. This minireview covers our recent advances on multicomponent reactions involving active methylene compounds  for the construction of bioactive molecule skeletons. In many cases, MW-assisted MCRs offer considerable improvements in selectivity, chemical yield and purity and constitutes a very simple and extremely rapid method to access a diverse range of heterocyclic motifs.
authors.affiliation: Xuzhou Normal University, P.R. China. laotu@xznu.edu.cn
authors.forename: Bo
authors.initials: B
authors.lastname: Jiang
authors.forename: Shu-Jiang
authors.initials: SJ
authors.lastname: Tu