title: Aortic valve replacement in patients with systemic mastocytosis.
abstract: Systemic mastocytosis is a hematologic disorder with important perioperative implications. A variety of stimuli and medications can cause severe anaphylaxis in these patients. We report successful preoperative, intraoperative, and postoperative management of a patient with systemic mastocytosis who underwent an aortic valve replacement and review the literature pertaining to cardiac surgery in these patients.
authors.affiliation: Department of Cardiovascular and Thoracic Surgery, Allegheny General Hospital, Pittsburgh, Pennsylvania 15212, USA.
authors.forename: Kelly M
authors.initials: KM
authors.lastname: Wanamaker
authors.forename: George J
authors.initials: GJ
authors.lastname: Magovern
authors.forename: Robert J
authors.initials: RJ
authors.lastname: Moraca
mesh_terms: D000368:Aged; D001024:Aortic Valve Stenosis / Q000150:complications / Q000601:surgery*; D005260:Female; D019918:Heart Valve Prosthesis Implantation / Q000379:methods*; D006801:Humans; D034721:Mastocytosis, Systemic / Q000150:complications*; D019990:Perioperative Care