title: [Proton magnetic resonance spectroscopy in the diagnosis of breast cancer].
abstract: Magnetic resonance spectroscopy (MRS) is used in mammalogy to specify the data obtained by traditional radiodiagnostic techniques and provides a possibility of estimating the molecular composition of pathologically altered breast tissues. This information is employed for the differential diagnosis of malignant and benign neoplasms, as well as for monitoring and predicting the efficiency of chemotherapy for breast cancer. Some technical problems and the lack of a standardized approach to the procedure of a study and interpretation of its results hinder the wide introduction of spectroscopy into clinical practice. This paper reviews the data available in the literature on proton MRS and the technical and clinical aspects of application of this technique.
authors.forename: N V
authors.initials: NV
authors.lastname: Meladze
authors.forename: P V
authors.initials: PV
authors.lastname: Kuchuk
authors.forename: A B
authors.initials: AB
authors.lastname: Abduraimov
authors.forename: K A
authors.initials: KA
authors.lastname: Les'ko
authors.forename: M A
authors.initials: MA
authors.lastname: Shariia
authors.forename: D S
authors.initials: DS
authors.lastname: Malik
authors.forename: S
authors.initials: S
authors.lastname: Matkhev
authors.forename: E A
authors.initials: EA
authors.lastname: Boĭko
mesh_terms: D000273:Adipose Tissue / Q000378:metabolism; D001940:Breast / Q000378:metabolism / Q000473:pathology*; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000378:metabolism / Q000628:therapy; D017024:Chemotherapy, Adjuvant / Q000379:methods; D003937:Diagnosis, Differential; D016903:Drug Monitoring / Q000379:methods*; D005260:Female; D006801:Humans; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*