title: Next-generation sequencing approaches for genetic mapping of complex diseases.
abstract: The advent of next generation sequencing technologies has opened new possibilities in the analysis of human disease. In this review we present the main next-generation sequencing technologies, with their major contributions and possible applications to the study of the genetic etiology of complex diseases.
authors.affiliation: Centre de Recherche du Centre Hospitalier Universitaire Sainte-Justine, Université de Montréal, Montréal, Québec, Canada. ferrancasalslopez@gmail.com
authors.forename: Ferran
authors.initials: F
authors.lastname: Casals
authors.forename: Youssef
authors.initials: Y
authors.lastname: Idaghdour
authors.forename: Julie
authors.initials: J
authors.lastname: Hussin
authors.forename: Philip
authors.initials: P
authors.lastname: Awadalla
mesh_terms: D002874:Chromosome Mapping / Q000379:methods / Q000639:trends*; D030342:Genetic Diseases, Inborn / Q000175:diagnosis / Q000235:genetics* / Q000503:physiopathology; D020022:Genetic Predisposition to Disease / Q000235:genetics*; D060005:Genotyping Techniques / Q000379:methods / Q000639:trends; D006801:Humans; D017422:Sequence Analysis, DNA / Q000379:methods / Q000639:trends