title: Design, synthesis and biological evaluation of noncovalent inhibitors of human CD38 NADase.
authors.affiliation: State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, 38 Xueyuan Road, Haidian District, Beijing 100191, China.
authors.forename: Yi
authors.initials: Y
authors.lastname: Zhou
authors.forename: Kai Yiu
authors.initials: KY
authors.lastname: Ting
authors.forename: Connie Mo Ching
authors.initials: CM
authors.lastname: Lam
authors.forename: Anna Ka Yee
authors.initials: AK
authors.lastname: Kwong
authors.forename: Jie
authors.initials: J
authors.lastname: Xia
authors.forename: Hongwei
authors.initials: H
authors.lastname: Jin
authors.forename: Zhenming
authors.initials: Z
authors.lastname: Liu
authors.forename: Liangren
authors.initials: L
authors.lastname: Zhang
authors.forename: Hon
authors.initials: H
authors.lastname: Cheung Lee
authors.forename: Lihe
authors.initials: L
authors.lastname: Zhang
mesh_terms: D051997:ADP-ribosyl Cyclase 1 / Q000037:antagonists & inhibitors* / Q000378:metabolism; D001665:Binding Sites; D020134:Catalytic Domain; D015195:Drug Design; D004789:Enzyme Activation / Q000187:drug effects; D004791:Enzyme Inhibitors / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D005663:Furans / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D006801:Humans; D010671:Phenylurea Compounds / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D013329:Structure-Activity Relationship
chemical_list: D004791:Enzyme Inhibitors; D005663:Furans; D010671:Phenylurea Compounds; D051997:ADP-ribosyl Cyclase 1