title: Antitumor cyclic hexapeptides from rubia plants: history, chemistry, and mechanism (2005-2011).
abstract: Rubiaceae-type cyclopeptides (RAs), cyclic hexapeptides from Rubia plants, have shown potential antitumor activity in vitro and in vivo. Based on the review about plant cyclopeptides (Chem. Rev., 2006, 106: 840), this mini-review will highlight new  progress on the discovery, synthesis, and mechanism of RAs isolated during 2005 to 2011, covering recent work in our group.
authors.affiliation: State Key Laboratory of Phytochemistry and Plant Resources in West China Kunming Institute of Botany Chinese Academy of Sciences Kunming 650201, China.
authors.forename: Si Meng
authors.initials: SM
authors.lastname: Zhao
authors.forename: Bin
authors.initials: B
authors.lastname: Kuang
authors.forename: Jun Ting
authors.initials: JT
authors.lastname: Fan
authors.forename: He
authors.initials: H
authors.lastname: Yan
authors.forename: Wen Yan
authors.initials: WY
authors.lastname: Xu
authors.forename: Ning Hua
authors.initials: NH
authors.lastname: Tan
mesh_terms: D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D002478:Cells, Cultured; D006801:Humans; D009842:Oligopeptides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D010456:Peptides, Cyclic / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D045470:Rubia / Q000737:chemistry*
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D009842:Oligopeptides; D010456:Peptides, Cyclic