title: [Apparatus for the measurement of the oxygen uptake of rats subjected to hypobaric hypoxia].
abstract: OBJECTIVE
  To construct an apparatus for the oxygen uptake measurement of rats exposed to hypobaric hypoxia at different simulated altitude.
  
  
  METHODS
  The capacity of this apparatus was about 0.01 m3. It included animal experimental cabin, reference cabin, altimeter, altitude vertical velocity indicator, pressure difference inductor and oxygen compensator, low scale manometer, soda lime and calcium chloride, small fan, thermometer, circulating water system and vacuum pump. The oxygen uptake of the rats at 6 000 m, 4 000 m and 1 000 m simulated altitude was measured using this apparatus.
  
  
  RESULTS
  The oxygen uptake of the rats at 50 m, 4 000 m and 6 000 m simulated altitude was (24.4 +/- 2.1), (10.8 +/- 2.0) and (8.8 +/- 1.6) ml O2/(kg x min) respectively (average +/- s, n = 10). The oxygen uptake decreased as altitude increased.
  
  
  CONCLUSIONS
  This apparatus can be used to measure the oxygen uptake of the rats at different simulated altitude.
authors.affiliation: Institute of Health and Environmental Medicine, Academg of Military Medical Sciences, Tianjing 300050, China.
authors.forename: Rui-Feng
authors.initials: RF
authors.lastname: Duan
authors.forename: Wen-Kao
authors.initials: WK
authors.lastname: Nan
authors.forename: Yi-Ping
authors.initials: YP
authors.lastname: Xing
authors.forename: Huai-Xin
authors.initials: HX
authors.lastname: Wang
authors.forename: Wen-Yu
authors.initials: WY
authors.lastname: Cui
authors.forename: Hai
authors.initials: H
authors.lastname: Wang
mesh_terms: D000531:Altitude; D000532:Altitude Sickness / Q000503:physiopathology; D000818:Animals; D003198:Computer Simulation; D004864:Equipment and Supplies; D000860:Hypoxia / Q000503:physiopathology*; D008297:Male; D010100:Oxygen / Q000378:metabolism*; D010101:Oxygen Consumption / Q000502:physiology*; D051381:Rats; D017207:Rats, Sprague-Dawley
chemical_list: D010100:Oxygen