title: A strategy for management of intraoperative Addisonian crisis during coronary artery bypass grafting.
abstract: Patients with Addison's disease undergoing cardiac surgery are at risk of developing a crisis. There is no consensus on the preoperative and intraoperative management of this group of patients undergoing cardiac surgery so the recommendations for non-cardiac patients are often used. The consensus statement from the international task force of the American College of Critical Care medicine recommends 100 mg of intravenous hydrocortisone for patients with adrenal insufficiency in septic shock, but in patients undergoing surgery, especially with extracorporeal circulation, the dosage may even be higher. We report our management of a patient with well-controlled adrenal insufficiency for 30 years who developed intraoperative Addisonian crisis despite the recommended preoperative corticosteroid supplementation. The importance of adequate corticosteroid supplementation for cardiac surgery patients, adapting the surgical strategy to allow for optimal management of potential complications and close monitoring with heightened awareness are discussed.
authors.affiliation: Lancashire Cardiac Centre, Blackpool Victoria Hospital, Blackpool,  UK.
authors.forename: Celma
authors.initials: C
authors.lastname: D'Silva
authors.forename: Dale
authors.initials: D
authors.lastname: Watson
authors.forename: Dumbor
authors.initials: D
authors.lastname: Ngaage
mesh_terms: D000224:Addison Disease / Q000097:blood / Q000150:complications / Q000188:drug therapy*; D001026:Coronary Artery Bypass / Q000009:adverse effects*; D023921:Coronary Stenosis / Q000150:complications / Q000601:surgery*; D005938:Glucocorticoids / Q000008:administration & dosage*; D006801:Humans; D006854:Hydrocortisone / Q000008:administration & dosage*; D008297:Male; D008875:Middle Aged; D011300:Preoperative Care; D012307:Risk Factors; D016896:Treatment Outcome
chemical_list: D005938:Glucocorticoids; D006854:Hydrocortisone