title: [Risk factors for postoperative acute kidney injury in a cohort of 2378 patients from 59 hospitals].
abstract: OBJECTIVE
  To assess risk factors for postoperative acute kidney injury (AKI) in adults with normal renal function hospitalized for major surgery. To analyze mortality and length of hospital stay in patients who develop postoperative AKI.
  
  
  METHODS
  Data for analysis were drawn from the 2006 ARISCAT study. The dependent variable was postoperative AKI defined as a decline in renal function demonstrated by a rise in plasma creatinine level to twice the baseline measurement or a 50% reduction in the glomerular filtration rate. Bivariate and multivariate analyses were used to identify preoperative and intraoperative risk factors.
  
  
  RESULTS
  We analyzed 2378 of the ARISCAT cases, which had been enrolled from 59 participating hospitals; 25 patients (1.1%) developed AKI. Analysis identified 5 risk factors: age, peripheral arterial disease, type of surgical incision, blood loss, and infusion of colloids. The area under the receiver operating characteristic curve was 0.88% (95% confidence interval, 0.79%-0.69%). Duration of hospital stay was longer for patients with postoperative AKI (21.8 days, vs 5.5 days for other patients; P=.007). Mortality was higher in patients with AKI at 30 days (36% vs 0.9%) and at 3 months (48% vs 1.7%).
  
  
  CONCLUSIONS
  The incidence of postoperative AKI was slightly over 1%. Knowledge of postoperative AKI risk factors can facilitate the planning of surgical interventions and anesthesia to reduce subsequent morbidity and mortality and length of hospital stay.
authors.affiliation: Servicio de Anestesiología, Fundació Puigvert (IUNA) Barcelona. 29285sst@comb.cat
authors.forename: S
authors.initials: S
authors.lastname: Sabaté
authors.forename: C
authors.initials: C
authors.lastname: Gomar
authors.forename: J
authors.initials: J
authors.lastname: Canet
authors.forename: P
authors.initials: P
authors.lastname: Sierra
authors.forename: J
authors.initials: J
authors.lastname: Castillo
mesh_terms: D058186:Acute Kidney Injury / Q000453:epidemiology*; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006761:Hospitals; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000453:epidemiology*; D018570:Risk Assessment; D012307:Risk Factors