title: [Serum immunoboichemical markers in patients suffered with hypertension-induced cerebrovascular diseases].
abstract: Complex evaluation neurotrophic protein S100b, differentiation factor HLDF, idio-and antiidiotypic antibodies against these proteins in patient sera with hypertension-induced cerebrovascular disorders was performed by ELISA. In patients with essential hypertension, cerebral hypertensive crisis and ischemic stroke S100b and anti-S100b concentration was found to be higher, whereas HLDF and anti-HLDF ones were lower compared with control. Different dynamics of S100b, HLDF content and antibody level was shown within 21 days of observation. These findings may be useful in further diagnostic and prognostic studies of hypertension-induced cerebrovascular disorders.
authors.forename: E I
authors.initials: EI
authors.lastname: Elistratova
authors.forename: M A
authors.initials: MA
authors.lastname: Gruden'
authors.forename: T V
authors.initials: TV
authors.lastname: Davydova
authors.forename: V V
authors.initials: VV
authors.lastname: Sherstnev
mesh_terms: D000368:Aged; D001323:Autoantibodies / Q000097:blood; D002561:Cerebrovascular Disorders / Q000097:blood* / Q000175:diagnosis / Q000209:etiology*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000097:blood* / Q000150:complications* / Q000175:diagnosis; D008297:Male; D008875:Middle Aged; D009363:Neoplasm Proteins / Q000097:blood; D009414:Nerve Growth Factors / Q000097:blood; D064568:S100 Calcium Binding Protein beta Subunit; D009418:S100 Proteins / Q000097:blood
chemical_list: D001323:Autoantibodies; D009363:Neoplasm Proteins; D009414:Nerve Growth Factors; D064568:S100 Calcium Binding Protein beta Subunit; D009418:S100 Proteins; C579160:S100B protein, human; C091149:cell differentiation factor 8.2-kDa