title: Thyroid Dysplasia in Wistar Hannover GALAS Rats.
abstract: Thyroid dysplasia was recognized in WistarHan GALAS rats and confirmed as a heritable congenital disorder. The gene or genes involved were not identified, but homozygous animals with thyroid dysplasia also exhibited stunted growth, had reduced pituitary gland growth hormone (GH) and were hypothyroid. Heterozygous animals exhibited thyroid dysplasia with normal thyroid hormonal homeostasis and no difference in the incidence of preneoplastic or neoplastic lesions in oncogenicity studies.
authors.forename: Klaus
authors.initials: K
authors.lastname: Weber
authors.forename: Rainer
authors.initials: R
authors.lastname: Ernst
authors.forename: Heinz
authors.initials: H
authors.lastname: Fankhauser
authors.forename: Jerry F
authors.initials: JF
authors.lastname: Hardisty
authors.forename: Wolfram
authors.initials: W
authors.lastname: Heider
authors.forename: Karla
authors.initials: K
authors.lastname: Stevens