title: Placental mesenchymal dysplasia: can early diagnosis ensure a good materno-foetal outcome? A case report.
abstract: Placental mesenchymal dysplasia is a rare disorder characterized by an increased size placenta with cystic villi and ectasic vessels. The correct diagnosis is very important, because placental mesenchymal dysplasia is usually compatible with a normal foetal morphology and a good materno-foetal outcome. An accurate ultrasound evaluation can help in the identification of characteristic patterns associated to this trophoblastic disease, particularly to distinguish it from its main differential diagnosis, i.e. hydatidiform mole. We report an early second-trimester ultrasound diagnosis of placental mesenchymal dysplasia complicated by foetal growth restriction, but with normal female karyotype and good healthy baby.
authors.affiliation: Department of Gynecological Sciences and Human Reproduction, University of Padua, Padua, Italy. salvatoregizzo@libero.it
authors.forename: Salvatore
authors.initials: S
authors.lastname: Gizzo
authors.forename: Stefania
authors.initials: S
authors.lastname: Di Gangi
authors.forename: Tito Silvio
authors.initials: TS
authors.lastname: Patrelli
authors.forename: Carlo
authors.initials: C
authors.lastname: Saccardi
authors.forename: Donato
authors.initials: D
authors.lastname: D'Antona
authors.forename: Giovanni Battista
authors.initials: GB
authors.lastname: Nardelli
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008648:Mesoderm / Q000473:pathology*; D009929:Organ Size; D010920:Placenta / Q000473:pathology*; D010922:Placenta Diseases / Q000175:diagnosis*; D011247:Pregnancy; D011256:Pregnancy Outcome; D016216:Ultrasonography, Prenatal