title: [Vigilance for veterinary medicinal products: declarations of adverse reactions in the year 2010].
abstract: In 2010, we observed again an increase in the number of declarations reported to the vigilance system for veterinary medicinal products up to a total of 160. The species and drug classes reported remained the same as in previous years: the majority of adverse drug reactions (ADRs) concerned either dogs or cats and the most frequently involved drugs were either antiparasitic products or antiinfectives. Adverse reactions following reconversions and 8 cases of suspected allergic reactions following the use of amoxicillin-clavulanic acid combinations in dogs were reported. Additional enquiries were processed by the Swiss Toxicological Information Centre and transmitted to Swiss medic. 11 of these reported accidental ingestions of flavoured tablets in overdose by dogs and some cats. The vaccino vigilance program received 179 declarations following immunization against blue tongue disease as well as 82 declarations following the application of other vaccines. The vigilance system increases the chance to identify rare reactions or interactions and thereby contributes to the security of veterinary medicinal products.
authors.affiliation: Institut für Veterinärpharmakologie und -toxikologie der Universität Zürich und Swissmedic, Schweizerisches Heilmittelinstitut, Bern. cedric.muentener@vetpharm.uzh.ch
authors.forename: C R
authors.initials: CR
authors.lastname: Müntener
authors.forename: L
authors.initials: L
authors.lastname: Bruckner
authors.forename: A
authors.initials: A
authors.lastname: Stürer
authors.forename: F R
authors.initials: FR
authors.lastname: Althaus
authors.forename: P
authors.initials: P
authors.lastname: Caduff-Janosa
mesh_terms: D016907:Adverse Drug Reaction Reporting Systems; D000818:Animals; D001819:Bluetongue / Q000517:prevention & control; D002415:Cats; D004285:Dogs; D064420:Drug-Related Side Effects and Adverse Reactions / Q000662:veterinary*; D011358:Product Surveillance, Postmarketing; D013557:Switzerland; D014612:Vaccines / Q000009:adverse effects; D019155:Veterinary Drugs / Q000009:adverse effects*
chemical_list: D014612:Vaccines; D019155:Veterinary Drugs