title: Antibacterial potential of benzoate and phenylethanoid derivatives isolated from Acanthus ilicifolius L. leaf extracts.
abstract: The antibacterial activities of column chromatography fractions of n-hexane, benzene, chloroform, acetone, ethanol and water extracts from Acanthus ilicifolius were tested against 24 bacterial pathogens. The antibacterial activity was performed using agar diffusion method. Most active fractions were further investigated through UV-Vis, (13)C, (1)H-NMR, FT-IR for the structural elucidation. The antibacterial activity of the extracts was identified as 6-hydroxy-benzoxazolinone, (Z)-4-coumaric acid 4-O-β-D-glucopyranoside and 3,5-dimethoxy-4-hydroxy methyl benzoate.
authors.affiliation: School of Marine Sciences, Department of Oceanography and Coastal Area Studies, Alagappa University, Thondi Campus, Thondi 623409, Ramanathapuram District, Tamil Nadu, India. ravibiotech201321@gmail.com
authors.forename: S
authors.initials: S
authors.lastname: Ravikumar
authors.forename: M
authors.initials: M
authors.lastname: Raja
authors.forename: M
authors.initials: M
authors.lastname: Gnanadesigan
mesh_terms: D027901:Acanthaceae / Q000737:chemistry*; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology*; D001565:Benzoates / Q000737:chemistry / Q000494:pharmacology; D001583:Benzoxazoles / Q000737:chemistry / Q000494:pharmacology; D003373:Coumaric Acids / Q000737:chemistry / Q000494:pharmacology; D004353:Drug Evaluation, Preclinical / Q000379:methods; D005960:Glucosides / Q000737:chemistry / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D010936:Plant Extracts / Q000737:chemistry*; D018515:Plant Leaves / Q000737:chemistry; D013056:Spectrophotometry, Ultraviolet; D017550:Spectroscopy, Fourier Transform Infrared
chemical_list: C580606:(Z)-4-coumaric acid 4-O-beta-D-glucopyranoside; C580605:3,5-dimethoxy-4-hydroxy methyl benzoate; C580604:6-hydroxy-benzoxazolinone; D000900:Anti-Bacterial Agents; D001565:Benzoates; D001583:Benzoxazoles; D003373:Coumaric Acids; D005960:Glucosides; D010936:Plant Extracts