title: No evidence of increased cortisol stress response in obese women with binge eating disorder.
abstract: Increased cortisol levels after stress have been associated with excessive food intake during binges in obese women with binge eating disorder (BED). The present study tried to replicate these findings in a sample of obese women with BED compared to obese women without BED. Twenty women with a mean BMI of 37.75 kg/m² were studied. Salivary cortisol was sampled before and after a socially evaluated cold pressure test at 8 time points. Both comparison groups showed the expected cortisol increase after the stressor (p<0.03), but no significant differences between groups emerged (p=0.96). These results do not support an increased stress reactivity of HPA in BED. Instead they would favour psychological explanations of binges, focusing on diminished perception of satiety.
authors.affiliation: Department of Clinical and Physiological Psychology, University of Trier, Trier, Germany.
authors.forename: S
authors.initials: S
authors.lastname: Schulz
authors.forename: R
authors.initials: R
authors.lastname: Laessle
authors.forename: D
authors.initials: D
authors.lastname: Hellhammer
mesh_terms: D000328:Adult; D056912:Binge-Eating Disorder / Q000097:blood / Q000503:physiopathology*; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000378:metabolism*; D009765:Obesity / Q000097:blood / Q000503:physiopathology*; D012463:Saliva / Q000378:metabolism; D013312:Stress, Physiological / Q000502:physiology*
chemical_list: D006854:Hydrocortisone