title: Modifications in the nitric acid oxidation of D-glucose.
abstract: The nitric acid oxidation of D-glucose was reinvestigated in an effort to better understand and improve the oxidation and subsequent work up steps. The oxidation was carried out using a computer controlled reactor employing a closed reaction flask under an atmosphere of oxygen which allowed for a catalytic oxidation process with oxygen as the terminal oxidant. Removal of nitric acid from product included the use of both diffusion dialysis and nanofiltration methodologies. Product analysis protocols were developed using ion chromatography.
authors.affiliation: Shafizadeh Rocky Mountain Center for Wood and Carbohydrate Chemistry, The University of Montana, Missoula, MT 59812, USA.
authors.forename: Tyler N
authors.initials: TN
authors.lastname: Smith
authors.forename: Kirk
authors.initials: K
authors.lastname: Hash
authors.forename: Cara-Lee
authors.initials: CL
authors.lastname: Davey
authors.forename: Heidi
authors.initials: H
authors.lastname: Mills
authors.forename: Holly
authors.initials: H
authors.lastname: Williams
authors.forename: Donald E
authors.initials: DE
authors.lastname: Kiely
mesh_terms: D002851:Chromatography, High Pressure Liquid; D004058:Diffusion; D005374:Filtration; D005937:Glucaric Acid / Q000737:chemistry; D005947:Glucose / Q000737:chemistry*; D036103:Nanotechnology; D017942:Nitric Acid / Q000737:chemistry* / Q000302:isolation & purification; D010084:Oxidation-Reduction
chemical_list: D017942:Nitric Acid; D005947:Glucose; D005937:Glucaric Acid