title: Consumption of fried foods and risk of coronary heart disease: Spanish cohort of the European Prospective Investigation into Cancer and Nutrition study.
abstract: OBJECTIVE
  To assess the association between consumption of fried foods and risk of coronary heart disease.
  
  
  METHODS
  Prospective cohort study.
  
  
  METHODS
  Spanish cohort of the European Prospective Investigation into Cancer and Nutrition.
  
  
  METHODS
  40 757 adults aged 29-69 and free of coronary heart disease at baseline (1992-6), followed up until 2004.
  
  
  METHODS
  Coronary heart disease events and vital status identified by record linkage with hospital discharge registers, population based registers of myocardial infarction, and mortality registers.
  
  
  RESULTS
  During a median follow-up of 11 years, 606 coronary heart disease events and 1135 deaths from all causes occurred. Compared with being in the first (lowest) quarter of fried food consumption, the multivariate hazard ratio of coronary heart disease in the second quarter was 1.15 (95% confidence interval 0.91 to 1.45), in the third quarter was 1.07 (0.83 to 1.38), and in the fourth quarter was 1.08 (0.82 to 1.43; P for trend 0.74). The results did not vary between those who used olive oil for frying and those who used sunflower oil. Likewise, no association was observed between fried food consumption and all cause mortality: multivariate hazard ratio for the highest versus the lowest quarter of fried food consumption was 0.93 (95% confidence interval 0.77 to 1.14; P for trend 0.98).
  
  
  CONCLUSIONS
  In Spain, a Mediterranean country where olive or sunflower oil is used for frying, the consumption of fried foods was not associated with coronary heart disease or with all cause mortality.
authors.affiliation: Department of Preventive Medicine and Public Health, School of Medicine, Autonomous University of Madrid, Spain. mpilar.guallar@uam.es
authors.forename: Pilar
authors.initials: P
authors.lastname: Guallar-Castillón
authors.forename: Fernando
authors.initials: F
authors.lastname: Rodríguez-Artalejo
authors.forename: Esther
authors.initials: E
authors.lastname: Lopez-Garcia
authors.forename: Luz M
authors.initials: LM
authors.lastname: León-Muñoz
authors.forename: Pilar
authors.initials: P
authors.lastname: Amiano
authors.forename: Eva
authors.initials: E
authors.lastname: Ardanaz
authors.forename: Larraitz
authors.initials: L
authors.lastname: Arriola
authors.forename: Aurelio
authors.initials: A
authors.lastname: Barricarte
authors.forename: Genevieve
authors.initials: G
authors.lastname: Buckland
authors.forename: María-Dolores
authors.initials: MD
authors.lastname: Chirlaque
authors.forename: Miren
authors.initials: M
authors.lastname: Dorronsoro
authors.forename: José-María
authors.initials: JM
authors.lastname: Huerta
authors.forename: Nerea
authors.initials: N
authors.lastname: Larrañaga
authors.forename: Pilar
authors.initials: P
authors.lastname: Marin
authors.forename: Carmen
authors.initials: C
authors.lastname: Martínez
authors.forename: Esther
authors.initials: E
authors.lastname: Molina
authors.forename: Carmen
authors.initials: C
authors.lastname: Navarro
authors.forename: J Ramón
authors.initials: JR
authors.lastname: Quirós
authors.forename: Laudina
authors.initials: L
authors.lastname: Rodríguez
authors.forename: María José
authors.initials: MJ
authors.lastname: Sanchez
authors.forename: Carlos A
authors.initials: CA
authors.lastname: González
authors.forename: Conchi
authors.initials: C
authors.lastname: Moreno-Iribas
mesh_terms: D000328:Adult; D000368:Aged; D000787:Angina Pectoris / Q000453:epidemiology*; D002423:Cause of Death; D003296:Cooking / Q000379:methods*; D003327:Coronary Disease / Q000453:epidemiology* / Q000401:mortality; D038441:Diet, Mediterranean; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000453:epidemiology*; D000069463:Olive Oil; D010938:Plant Oils / Q000008:administration & dosage; D011446:Prospective Studies; D012307:Risk Factors; D013030:Spain / Q000453:epidemiology; D000074242:Sunflower Oil; D011795:Surveys and Questionnaires
chemical_list: D000069463:Olive Oil; D010938:Plant Oils; D000074242:Sunflower Oil