title: Endogenous endophthalmitis with an unusual infective agent: Actinomyces neuii.
abstract: OBJECTIVE
  To report an unusual case of a patient with endogenous endophthalmitis caused by Actinomyces neuii.
  
  
  RESULTS
  A 69-year-old woman in an immunosuppressed state and who had a previous history of periappendicular abscess presented with bilateral red painful eyes. The diagnosis was confirmed by culture and pan-bacterial polymerase chain reaction drawn from anterior chamber sample. On admission, the patient underwent an intravitreal injection of vancomycin combined with ceftazidime. Following a 3-week treatment of intravenous penicillin and topical sulfacetamide sodium, the patient recovered fully.
  
  
  CONCLUSIONS
  Actinomyces neuii can cause endogenous endophthalmitis. Intravenous penicillin G is an effective treatment leading to favorable prognosis.
authors.affiliation: Department of Ophthalmology, Bruch Padeh Medical Center, Poriya, Israel. sgraffi@walla.com
authors.forename: Shmuel
authors.initials: S
authors.lastname: Graffi
authors.forename: Avi
authors.initials: A
authors.lastname: Peretz
authors.forename: Modi
authors.initials: M
authors.lastname: Naftali
mesh_terms: D000190:Actinomyces / Q000235:genetics / Q000302:isolation & purification*; D000196:Actinomycosis / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D000287:Administration, Topical; D000368:Aged; D000867:Anterior Chamber / Q000382:microbiology; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002442:Ceftazidime / Q000627:therapeutic use; D004269:DNA, Bacterial / Q000032:analysis; D004359:Drug Therapy, Combination; D009877:Endophthalmitis / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D015818:Eye Infections, Bacterial / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D005260:Female; D006801:Humans; D007262:Infusions, Intravenous; D058449:Intravitreal Injections; D010400:Penicillin G / Q000627:therapeutic use; D016133:Polymerase Chain Reaction; D013409:Sulfacetamide / Q000627:therapeutic use; D014640:Vancomycin / Q000627:therapeutic use
chemical_list: D000900:Anti-Bacterial Agents; D004269:DNA, Bacterial; D013409:Sulfacetamide; D014640:Vancomycin; D002442:Ceftazidime; D010400:Penicillin G