title: Copper-catalyzed aerobic [3+2]-annulation of N-alkenyl amidines.
abstract: A method for the synthesis of bi- and tricyclic amidines has been developed through copper-catalyzed aerobic [3+2]-annulation reaction of N-alkenyl amidines. These cyclic amidines could be converted into mono-benzyl-protected vicinal diamines by the reduction with aluminum hydride.
authors.affiliation: Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore.
authors.forename: Yi-Feng
authors.initials: YF
authors.lastname: Wang
authors.forename: Xu
authors.initials: X
authors.lastname: Zhu
authors.forename: Shunsuke
authors.initials: S
authors.lastname: Chiba
mesh_terms: D000578:Amidines / Q000138:chemical synthesis* / Q000737:chemistry*; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D003500:Cyclization; D015394:Molecular Structure
chemical_list: D000578:Amidines; D003300:Copper