title: Hormesis: why it is important to biogerontologists.
abstract: This paper offers a broad assessment of the hormetic dose response and its relevance to biogerontology. The paper provides detailed background information on the historical foundations of hormesis, its quantitative features, mechanistic foundations, as well as how the hormesis concept could be further applied in the development of new therapeutic advances in the treatment of age-related diseases. The concept of hormesis has direct application to biogerontology not only affecting the quality of the aging process but also experimental attempts to extend longevity.
authors.affiliation: Department of Public Health, Environmental Health Sciences, University of Massachusetts, Amherst, 01003, USA. edwardc@schoolph.umass.edu
authors.forename: Edward J
authors.initials: EJ
authors.lastname: Calabrese
authors.forename: Ivo
authors.initials: I
authors.lastname: Iavicoli
authors.forename: Vittorio
authors.initials: V
authors.lastname: Calabrese
mesh_terms: D005853:Geriatrics; D059165:Hormesis; D006801:Humans