title: Stimuli pH-responsive (N-vinyl imidazole-co-acryloylmorpholine) hydrogels; mesoporous and nanoporous scaffolds.
abstract: Tunable mesoporosity and nanoporosity of stimuli pH-responsive (N-vinyl imidazole-ran-acryloylmorpholine) hydrogels studied in terms of %swelling at various ionic strength, pH, temperature, and crosslinker concentration values were investigated. Hydrogel properties including diffusional exponent, number of links between two crosslinks, rms end-to-end distance and mesh size of gels were evaluated. The structural sequence of the scaffolds was tested and verified using Kelen-Tudos technique, and Alfrey-Price relationship. Hydrogels were characterized using FTIR, thermogravimetric analysis, differential scanning calorimetry, and freeze-dried Scanning electron micrographs techniques. The reversible pH responsiveness and possible mesoporous and nanoporous (i.e., 0.88-4.03 nm) structures suggest their suitable candidate in membrane technology and/or is an adequate drug delivery vehicle in drug delivery systems.
authors.affiliation: Department of Applied Chemistry, Faculty of Science and Arts, Jordan University of Science and Technology, Irbid, Jordan. fares@just.edu.jo
authors.forename: Mohammad M
authors.initials: MM
authors.lastname: Fares
authors.forename: Ahmad M
authors.initials: AM
authors.lastname: Al-Shboul
mesh_terms: D002152:Calorimetry, Differential Scanning; D020100:Hydrogels; D006863:Hydrogen-Ion Concentration; D007093:Imidazoles / Q000737:chemistry*; D008855:Microscopy, Electron, Scanning; D009025:Morpholines / Q000737:chemistry*; D017550:Spectroscopy, Fourier Transform Infrared; D013818:Thermogravimetry
chemical_list: D020100:Hydrogels; D007093:Imidazoles; D009025:Morpholines