title: RIP3 finds partners in crime.
abstract: Programmed necrosis has long been recognized as a crucial component of animal development; however, the signaling pathway beyond the protein kinases RIP1 and RIP3 remains largely unknown. Sun et al. and Wang et al. now identify critical factors downstream of RIP1 and RIP3 in programmed necrosis, extending our understanding of this form of cell death.
authors.affiliation: Department of Pathology, University of Massachusetts Medical School, Worcester, MA 01505, USA. francis.chan@umassmed.edu
authors.forename: Francis Ka-Ming
authors.initials: FK
authors.lastname: Chan
authors.forename: Eric H
authors.initials: EH
authors.lastname: Baehrecke