title: Determination of perfluorooctane sulfonate and perfluorooctanoic acid in food packaging using liquid chromatography coupled with tandem mass spectrometry.
abstract: This research aimed to monitor the amounts of PFOS and PFOA in food packaging and study the migration of PFOS and PFOA from food packaging, using a saliva simulant and pressurized liquid extraction (PLE) technique. Liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS) was employed to determine residues of PFOS and PFOA by using a gradient reversed-phase method with ammonium acetate/acetonitrile buffer. A good linearity was established for PFOS and PFOA in a range of 0.05-10 μgL(-1), with R2 ≥ 0.9998. Of the samples extracted by methanol, the highest concentration of PFOS was found in fast-food container samples, at a level of 92.48 ng dm(-2). For PFOA, the highest concentration in samples extracted by methanol was found in ice cream cup samples, at a level of 16.91 ng dm(-2). The amounts of PFOS and PFOA that migrated from food packaging samples through contact with saliva simulant were 4.80 and 4.55 ng dm(-2), respectively. Saliva simulant could leach PFOS and PFOA from the group of the thickest paper samples (≤1 dm2 g(-1)) at levels of 7.01 and 6.41 ng dm(-2), respectively, indicating that paper with greater thickness and less area might release larger quantities of coated/added PFOS or PFOA.
authors.affiliation: Department of Civil and Environmental Engineering, Faculty of Engineering, Mahidol University, Phutthamonthon, Nakorn Pathom, Thailand.
authors.forename: Somrutai
authors.initials: S
authors.lastname: Poothong
authors.forename: Suwanna Kitpati
authors.initials: SK
authors.lastname: Boontanon
authors.forename: Narin
authors.initials: N
authors.lastname: Boontanon
mesh_terms: D017738:Alkanesulfonic Acids / Q000032:analysis*; D002210:Caprylates / Q000032:analysis*; D002851:Chromatography, High Pressure Liquid; D005466:Fluorocarbons / Q000032:analysis*; D005506:Food Contamination; D018857:Food Packaging; D010209:Paper; D012463:Saliva / Q000737:chemistry; D053719:Tandem Mass Spectrometry
chemical_list: D017738:Alkanesulfonic Acids; D002210:Caprylates; D005466:Fluorocarbons; C023036:perfluorooctanoic acid; C076994:perfluorooctane sulfonic acid