title: National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease.
abstract: A consensus panel from the United States and Europe was convened recently to update and revise the 1997 consensus guidelines for the neuropathologic evaluation of Alzheimer's disease (AD) and other diseases of brain that are common in the elderly. The new guidelines recognize the pre-clinical stage of AD, enhance the assessment of AD to include amyloid accumulation as well as neurofibrillary change and neuritic plaques, establish protocols for the neuropathologic assessment of Lewy body disease, vascular brain injury, hippocampal sclerosis, and TDP-43 inclusions, and recommend standard approaches for the workup of cases and their clinico-pathologic correlation.
authors.affiliation: Department of Neurology, Massachusetts General Hospital, Harvard University, Boston, MA, USA.
authors.forename: Bradley T
authors.initials: BT
authors.lastname: Hyman
authors.forename: Creighton H
authors.initials: CH
authors.lastname: Phelps
authors.forename: Thomas G
authors.initials: TG
authors.lastname: Beach
authors.forename: Eileen H
authors.initials: EH
authors.lastname: Bigio
authors.forename: Nigel J
authors.initials: NJ
authors.lastname: Cairns
authors.forename: Maria C
authors.initials: MC
authors.lastname: Carrillo
authors.forename: Dennis W
authors.initials: DW
authors.lastname: Dickson
authors.forename: Charles
authors.initials: C
authors.lastname: Duyckaerts
authors.forename: Matthew P
authors.initials: MP
authors.lastname: Frosch
authors.forename: Eliezer
authors.initials: E
authors.lastname: Masliah
authors.forename: Suzanne S
authors.initials: SS
authors.lastname: Mirra
authors.forename: Peter T
authors.initials: PT
authors.lastname: Nelson
authors.forename: Julie A
authors.initials: JA
authors.lastname: Schneider
authors.forename: Dietmar Rudolf
authors.initials: DR
authors.lastname: Thal
authors.forename: Bill
authors.initials: B
authors.lastname: Thies
authors.forename: John Q
authors.initials: JQ
authors.lastname: Trojanowski
authors.forename: Harry V
authors.initials: HV
authors.lastname: Vinters
authors.forename: Thomas J
authors.initials: TJ
authors.lastname: Montine
mesh_terms: D000544:Alzheimer Disease / Q000175:diagnosis* / Q000453:epidemiology; D001921:Brain / Q000473:pathology*; D015975:Consensus Development Conferences, NIH as Topic; D006801:Humans; D054561:National Institute on Aging (U.S.) / Q000592:standards*; D017410:Practice Guidelines as Topic / Q000592:standards*; D012955:Societies, Medical / Q000592:standards*; D014481:United States / Q000453:epidemiology