title: The incidence of C5 palsy after multilevel cervical decompression procedures: a review of 750 consecutive cases.
abstract: METHODS
  Retrospective review of 750 consecutive multilevel cervical spine decompression surgeries performed by a single spine surgeon.
  
  
  OBJECTIVE
  To determine the incidence of C5 palsy in a large consecutive series of multilevel cervical spine decompression procedures.
  
  
  BACKGROUND
  Palsy of the C5 nerve is a well-known potential complication of cervical spine surgery with reported rates ranging from 0% to 30%. The etiology remains uncertain but has been attributed to iatrogenic injury during surgery, tethering from shifting of the spinal cord, spinal cord ischemia, and reperfusion injury of the spinal cord.
  
  
  METHODS
  We included patients undergoing multilevel cervical corpectomy, corpectomy with posterior fusion, posterior laminectomy and fusion, and laminoplasty. Exclusion criteria included lack of follow-up data, spinal cord injury preventing preoperative or postoperative motor testing, or surgery not involving the C5 level. Incidence of C5 palsy was determined and compared to determine whether significant differences existed among the various procedures, patient age, sex, revision surgery, preoperative weakness, diabetes, smoking, number of levels decompressed, and history of previous upper extremity surgery.
  
  
  RESULTS
  Of the 750 patients, 120 were eliminated on the basis of the exclusion criteria. The 630 patients included in the analysis consisted of 292 females and 338 males. The mean age was 58 years (range, 19-87). The incidence of C5 nerve palsy for the entire group was 42 of 630 (6.7%). The incidence was highest for the laminectomy and fusion group (9.5%), followed by the corpectomy with posterior fusion group (8.4%), the corpectomy group (5.1%), and finally the laminoplasty group (4.8%), although these differences did not reach statistical significance. There was a significantly higher incidence in males (8.6% vs. 4.5%, P = 0.05).
  
  
  CONCLUSIONS
  Incidence of C5 nerve palsy after cervical spine decompression was 6.7%. This is consistent with previously published studies and represents the largest series of North American patients to date. There is no statistically significant difference in incidence of C5 palsy based on surgical procedure, although there was a trend toward higher rates with laminectomy and fusion.
authors.affiliation: Department of Orthopaedic Surgery, Mayo Clinic, Rochester, MN, USA. nassr.ahmad@mayo.edu
authors.forename: Ahmad
authors.initials: A
authors.lastname: Nassr
authors.forename: Jason C
authors.initials: JC
authors.lastname: Eck
authors.forename: Ravi K
authors.initials: RK
authors.lastname: Ponnappan
authors.forename: Rami R
authors.initials: RR
authors.lastname: Zanoun
authors.forename: William F
authors.initials: WF
authors.lastname: Donaldson
authors.forename: James D
authors.initials: JD
authors.lastname: Kang
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001917:Brachial Plexus / Q000293:injuries* / Q000473:pathology / Q000601:surgery; D020516:Brachial Plexus Neuropathies / Q000453:epidemiology*; D002574:Cervical Vertebrae / Q000601:surgery; D019299:Decompression, Surgical / Q000009:adverse effects* / Q000379:methods; D005260:Female; D006801:Humans; D015994:Incidence; D007431:Intraoperative Complications / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013126:Spinal Nerve Roots / Q000293:injuries* / Q000473:pathology* / Q000601:surgery; D055815:Young Adult