title: Reduction of dyskinesias and psychiatric disability with clozapine over different time courses.
abstract: Nine subjects with schizophrenia or schizoaffective disorder were treated with clozapine, 500 mg/day for at least 3 months. Each was affected by tardive dyskinesia whose severity was reduced significantly after 3 months of treatment but not at earlier monthly assessments. In contrast, psychiatric symptoms were lessened significantly after 1 month. The more delayed improvement of dyskinesia as compared to the pace of psychiatric improvement suggests a differential effect of the drug.
authors.affiliation: Mercer University School of Medicine, 1550 College Street, Macon, GA 31207.
authors.forename: N C
authors.initials: NC
authors.lastname: Moore
authors.forename: P A
authors.initials: PA
authors.lastname: Lewitt
authors.forename: S
authors.initials: S
authors.lastname: Gershon