title: Effect of 900 MHz radio frequency radiation on beta amyloid protein, protein carbonyl, and malondialdehyde in the brain.
abstract: Recently, many studies have been carried out in relation to 900 MHz radiofrequency radiation (RF) emitted from a mobile phone on the brain. However, there is little data concerning possible mechanisms between long-term exposure of RF radiation and biomolecules in brain. Therefore, we aimed to investigate long-term effects of 900 MHz radiofrequency radiation on beta amyloid protein, protein carbonyl, and malondialdehyde in the rat brain. The study was carried out on 17 Wistar Albino adult male rats. The rat heads in a carousel were exposed to 900 MHz radiofrequency radiation emitted from a generator, simulating mobile phones. For the study group (n: 10), rats were exposed to the radiation 2 h per day (7 days a week) for 10 months. For the sham group (n: 7), rats were placed into the carousel and the same procedure was applied except that the generator was turned off. In this study, rats were euthanized after 10 months of exposure and their brains were removed. Beta amyloid protein, protein carbonyl, and malondialdehyde levels were found to be higher in the brain of rats exposed to 900 MHz radiofrequency radiation. However, only the increase of protein carbonyl in the brain of rats exposed to 900 MHz radiofrequency radiation was found to be statistically significant (p<0.001). In conclusion, 900 MHz radiation emitted from mobile/cellular phones can be an agent to alter some biomolecules such as protein. However, further studies are necessary.
authors.affiliation: Department of Biophysics, Medical School of Dicle University, Diyarbakir, Turkey. sdasdag@gmail.com
authors.forename: Suleyman
authors.initials: S
authors.lastname: Dasdag
authors.forename: Mehmet Zulkuf
authors.initials: MZ
authors.lastname: Akdag
authors.forename: Goksel
authors.initials: G
authors.lastname: Kizil
authors.forename: Murat
authors.initials: M
authors.lastname: Kizil
authors.forename: Dilek Ulker
authors.initials: DU
authors.lastname: Cakir
authors.forename: Beran
authors.initials: B
authors.lastname: Yokus
mesh_terms: D016229:Amyloid beta-Peptides / Q000378:metabolism*; D000818:Animals; D001921:Brain / Q000378:metabolism* / Q000528:radiation effects*; D008297:Male; D008315:Malondialdehyde / Q000378:metabolism*; D050050:Protein Carbonylation / Q000528:radiation effects*; D011846:Radio Waves / Q000009:adverse effects*; D051381:Rats; D017208:Rats, Wistar; D013997:Time Factors
chemical_list: D016229:Amyloid beta-Peptides; D008315:Malondialdehyde