title: Sudden reversible pacemaker failure in a patient with cardiac sarcoidosis: an unfortunate case of ventricular septal pacing.
abstract: We report a case of sudden marked deterioration of ventricular stimulation threshold resulting in pacemaker failure 16 months after a ventricular septal lead implantation for atrioventricular block. Echocardiography revealed septal wall thinning at the electrode-tissue interface, which was not detected pre-operatively. Endomyocardial biopsy confirmed cardiac sarcoidosis. The increased threshold was reversible with prednisolone.
authors.affiliation: Division of Cardiovascular Medicine, Department of Internal Medicine, Gifu University School of Medicine, 1-1 Yanagido, Gifu 501-1194, Japan. konezumi@ccn3.aitai.ne.jp
authors.forename: Nobuhiro
authors.initials: N
authors.lastname: Takasugi
authors.forename: Tomoki
authors.initials: T
authors.lastname: Kubota
authors.forename: Itta
authors.initials: I
authors.lastname: Kawamura
authors.forename: Mieko
authors.initials: M
authors.lastname: Takasugi
authors.forename: Hiromitsu
authors.initials: H
authors.lastname: Kanamori
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Ushikoshi
authors.forename: Arihiro
authors.initials: A
authors.lastname: Hattori
authors.forename: Takuma
authors.initials: T
authors.lastname: Aoyama
authors.forename: Masanori
authors.initials: M
authors.lastname: Kawasaki
authors.forename: Kazuhiko
authors.initials: K
authors.lastname: Nishigaki
authors.forename: Genzou
authors.initials: G
authors.lastname: Takemura
authors.forename: Shinya
authors.initials: S
authors.lastname: Minatoguchi
mesh_terms: D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D054537:Atrioventricular Block / Q000150:complications / Q000517:prevention & control*; D009202:Cardiomyopathies / Q000188:drug therapy* / Q000209:etiology*; D006801:Humans; D008297:Male; D010138:Pacemaker, Artificial / Q000009:adverse effects*; D011239:Prednisolone / Q000627:therapeutic use*; D011475:Prosthesis Failure; D012507:Sarcoidosis / Q000188:drug therapy* / Q000209:etiology*; D016896:Treatment Outcome; D054088:Ventricular Septum
chemical_list: D000893:Anti-Inflammatory Agents; D011239:Prednisolone