title: A case of Castleman's disease mimicking a hepatocellular carcinoma: a case report and review of literature.
abstract: Castleman's disease is a rare disease characterized by lymph node hyperplasia. Although Castleman's disease can occur wherever lymphoid tissue is found, it rarely appears in the abdominal cavity, and is especially rare adjacent to the liver. Here, we report a rare case of Castleman's disease in the portal area that mimicked a hepatocellular carcinoma (HCC) in a chronic hepatitis B patient. A 40 year-old woman with chronic hepatitis B presented with right upper quadrant discomfort. Computed tomography and magnetic resonance imaging results showed a 2.2 cm-sized, exophytic hypervascular mass in the portal area. HCC was suspected. However, histologic examination revealed Castleman's disease. We suggest that Castleman's disease should be included as a rare differential diagnosis of a hypervascular mass in the portal area, even in patients with chronic hepatitis B.
authors.affiliation: Department of Internal Medicine and Hepatology Center, Bundang Jesaeng General Hospital, Seongnam, Korea.
authors.forename: Sung Yeol
authors.initials: SY
authors.lastname: Jang
authors.forename: Bo Hyun
authors.initials: BH
authors.lastname: Kim
authors.forename: Jung Hee
authors.initials: JH
authors.lastname: Kim
authors.forename: Sung-Hae
authors.initials: SH
authors.lastname: Ha
authors.forename: Jeong Ah
authors.initials: JA
authors.lastname: Hwang
authors.forename: Jae Woo
authors.initials: JW
authors.lastname: Yeon
authors.forename: Ki Ho
authors.initials: KH
authors.lastname: Kim
authors.forename: So Ya
authors.initials: SY
authors.lastname: Paik
mesh_terms: D000328:Adult; D006528:Carcinoma, Hepatocellular / Q000175:diagnosis; D005871:Castleman Disease / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D019694:Hepatitis B, Chronic / Q000150:complications / Q000175:diagnosis; D006801:Humans; D007150:Immunohistochemistry; D008113:Liver Neoplasms / Q000175:diagnosis; D008279:Magnetic Resonance Imaging; D017464:Receptors, Complement 3d / Q000378:metabolism; D014057:Tomography, X-Ray Computed
chemical_list: D017464:Receptors, Complement 3d