title: [Rheumatoid arthritis and cardiovascular disease: what is known about this relationship and what can currently be done for affected patients?].
abstract: There is increasing interest in autoimmune diseases, especially their relationship with cardiovascular disease. Rheumatoid arthritis in particular has been considered an independent risk factor for coronary artery disease in recent years. Various studies have aimed to clarify important aspects of risk stratification and treatment options in patients with rheumatoid arthritis, and specific therapies are being studied that promise to reduce their long-term cardiovascular risk. We performed a wide-ranging review of the literature to highlight the importance of atherosclerotic and inflammatory mechanisms in coronary artery disease. We also suggest strategies for risk stratification and treatment of cardiovascular disease in patients with rheumatoid arthritis.
authors.affiliation: Instituto do Coraçã do do Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brasil. alexandre.soeiro@bol.com.br
authors.forename: Alexandre de Matos
authors.initials: Ade M
authors.lastname: Soeiro
authors.forename: Michel
authors.initials: M
authors.lastname: Haddad
authors.forename: Maria Carolina Feres
authors.initials: MC
authors.lastname: de Almeida
authors.forename: Aline D
authors.initials: AD
authors.lastname: Ruppert
authors.forename: Carlos V
authors.initials: CV
authors.lastname: Serrano
mesh_terms: D001172:Arthritis, Rheumatoid / Q000150:complications* / Q000503:physiopathology; D002318:Cardiovascular Diseases / Q000150:complications*; D006801:Humans; D007249:Inflammation / Q000209:etiology; D012307:Risk Factors