title: Place preference test in rodents.
abstract: Conditioned place preference is a behavioral model currently used to measure the rewarding properties induced by the administration of a drug. In this paradigm, the rewarding properties of a compound are associated with the particular characteristics of a given environment. Advantages of this test are the absence of any instrumental learning and the possibility of evaluating reinforcing effects in the absence of the test substance. Due to the recent availability of multiple lines of genetically modified mice, this unit has been updated to include procedures for testing place preference in both rats and mice. Details are also provided for evaluating drug effects using this procedure.
authors.affiliation: Porsolt and Partners Pharmacology, Boulogne Billancourt, France.
authors.forename: Sylvain
authors.initials: S
authors.lastname: Roux
authors.forename: Christelle
authors.initials: C
authors.lastname: Froger
authors.forename: Roger D
authors.initials: RD
authors.lastname: Porsolt
authors.forename: Olga
authors.initials: O
authors.lastname: Valverde
authors.forename: Rafael
authors.initials: R
authors.lastname: Maldonado
mesh_terms: D000822:Animal Husbandry; D000818:Animals; D003213:Conditioning, Psychological / Q000187:drug effects*; D004780:Environment, Controlled; D008297:Male; D051379:Mice; D009042:Motivation / Q000187:drug effects*; D004364:Pharmaceutical Preparations; D051381:Rats; D017208:Rats, Wistar; D012054:Reinforcement, Psychology; D012201:Reward; D013048:Specimen Handling
chemical_list: D004364:Pharmaceutical Preparations