title: Excessive daytime sleepiness and narcolepsy--an approach to investigation and management.
abstract: Excessive daytime sleepiness is a common presentation to physicians both in general practice and hospital settings. In this review, we provide an update on the latest theories on the pathogenesis of the condition, and discuss the approach to investigation of the sleepy patient, with particular reference to narcolepsy. Recommended therapy is reviewed for both narcolepsy and cataplexy, to provide physicians with an important reference on the investigation and management of these troubling conditions.
authors.affiliation: Department of Neurology, Ninewells Hospital, Dundee DD1 9SY, United Kingdom. ian_m@doctors.org.uk
authors.forename: Ian
authors.initials: I
authors.lastname: Morrison
authors.forename: Renata L
authors.initials: RL
authors.lastname: Riha
mesh_terms: D000818:Animals; D000928:Antidepressive Agents / Q000627:therapeutic use*; D000697:Central Nervous System Stimulants / Q000627:therapeutic use*; D003937:Diagnosis, Differential; D006970:Disorders of Excessive Somnolence / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology; D006801:Humans; D009290:Narcolepsy / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology; D017286:Polysomnography; D012894:Sleep Stages / Q000502:physiology*
chemical_list: D000928:Antidepressive Agents; D000697:Central Nervous System Stimulants