title: Conceptually new entries into cells.
abstract: This article summarizes the background and a few preliminary results concerning project 7 of the NCCR Chemical Biology. The general objective is to explore new concepts for cellular uptake, membrane tunneling, sensing and labeling. Emphasis is on the use of dynamic covalent chemistry  for counterion activation, slow release of polyions and fluorescent probes, and the generation of activator libraries and polyions that grow and shrink.
authors.affiliation: School of Chemistry and Biochemistry, University of Geneva, CH-1211 Geneva, Switzerland.
authors.forename: Javier
authors.initials: J
authors.lastname: Montenegro
authors.forename: Charlotte
authors.initials: C
authors.lastname: Gehin
authors.forename: Eun-Kyoung
authors.initials: EK
authors.lastname: Bang
authors.forename: Andrea
authors.initials: A
authors.lastname: Fin
authors.forename: David Alonso
authors.initials: DA
authors.lastname: Doval
authors.forename: Howard
authors.initials: H
authors.lastname: Riezman
authors.forename: Naomi
authors.initials: N
authors.lastname: Sakai
authors.forename: Stefan
authors.initials: S
authors.lastname: Matile
mesh_terms: D001692:Biological Transport; D001695:Biology; D008051:Lipid Bilayers; D034741:RNA, Small Interfering
chemical_list: D008051:Lipid Bilayers; D034741:RNA, Small Interfering