title: Distinct peak at 3.8 ppm observed by 3T MR spectroscopy in meningiomas,             while nearly absent in high-grade gliomas and cerebral metastases.
abstract: The purpose of the present study was to evaluate distinct metabolic features of meningiomas to distinguish them from other brain lesions using proton magnetic resonance spectroscopy. The study was performed on 17 meningiomas, 24 high-grade gliomas and 9 metastases. Elevated signal intensity at 3.8 ppm observed in low TE spectra adequately differentiated meningioma from other brain tumors while alanine was not indicative of meningioma occurrence; the presence of lipids and lactate did not provide a strong index for meningioma malignancy.
authors.affiliation: Department of Medical Physics, University of Thessaly, Biopolis,                     Larissa 41110, Greece.
authors.forename: Evanthia
authors.initials: E
authors.lastname: Kousi
authors.forename: Ioannis
authors.initials: I
authors.lastname: Tsougos
authors.forename: Konstantinos
authors.initials: K
authors.lastname: Fountas
authors.forename: Kiriaki
authors.initials: K
authors.lastname: Theodorou
authors.forename: Evaggelia
authors.initials: E
authors.lastname: Tsolaki
authors.forename: Ioannis
authors.initials: I
authors.lastname: Fezoulidis
authors.forename: Eftichia
authors.initials: E
authors.lastname: Kapsalaki
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001932:Brain Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000556:secondary; D005910:Glioma / Q000000981:diagnostic imaging / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D009682:Magnetic Resonance Spectroscopy; D008577:Meningeal Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D008579:Meningioma / Q000000981:diagnostic imaging / Q000473:pathology*; D008875:Middle Aged; D011877:Radionuclide Imaging