title: Whole blood is the sample matrix of choice for monitoring systemic triclocarban levels.
abstract: The antibacterial triclocarban (TCC) concentrates in the cellular fraction of blood. Consequently, plasma levels are at least two-fold lower than the TCC amount present in blood. Utilizing whole blood sampling, a low but significant absorption of TCC from soap during showering is demonstrated for a small group of human subjects.
authors.affiliation: Institute of Toxicology and Chemical Analysis, University of Veterinary Medicine, Hannover, Germany.
authors.forename: Nils Helge
authors.initials: NH
authors.lastname: Schebb
authors.forename: Ki Chang
authors.initials: KC
authors.lastname: Ahn
authors.forename: Hua
authors.initials: H
authors.lastname: Dong
authors.forename: Shirley J
authors.initials: SJ
authors.lastname: Gee
authors.forename: Bruce D
authors.initials: BD
authors.lastname: Hammock
mesh_terms: D000818:Animals; D000891:Anti-Infective Agents, Local / Q000097:blood*; D001774:Blood Chemical Analysis / Q000379:methods*; D002224:Carbanilides / Q000097:blood*; D004781:Environmental Exposure / Q000032:analysis; D008297:Male; D051379:Mice
chemical_list: D000891:Anti-Infective Agents, Local; D002224:Carbanilides; C009540:triclocarban