title: Development of radiolabeled compounds for myocardial perfusion imaging.
abstract: Coronary artery disease (CAD) is the main cause of death and remains a major health problem worldwide. Myocardial perfusion imaging is a well established noninvasive method for assessing CAD. This review summarizes the development of various radiotracers for myocardial perfusion imaging, including single photon emission computed tomography (SPECT) perfusion imaging agents and positron emission tomography (PET) perfusion imaging agents and introduces novel basic research data related to this area. In addition, the current state of the art in myocardial perfusion imaging agents and the future direction are discussed in this review.
authors.affiliation: College of Chemistry, Beijing Normal University, Beijing, China.
authors.forename: Xiao
authors.initials: X
authors.lastname: Lin
authors.forename: Junbo
authors.initials: J
authors.lastname: Zhang
authors.forename: Xuebin
authors.initials: X
authors.lastname: Wang
authors.forename: Zhigang
authors.initials: Z
authors.lastname: Tang
authors.forename: Xianzhong
authors.initials: X
authors.lastname: Zhang
authors.forename: Jie
authors.initials: J
authors.lastname: Lu
mesh_terms: D000818:Animals; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging*; D015195:Drug Design; D006801:Humans; D055414:Myocardial Perfusion Imaging / Q000379:methods*; D049268:Positron-Emission Tomography / Q000379:methods; D019275:Radiopharmaceuticals; D015899:Tomography, Emission-Computed, Single-Photon / Q000379:methods
chemical_list: D019275:Radiopharmaceuticals