title: First description of KPC-2-producing Pseudomonas putida in Brazil.
abstract: This work reports the identification of the first case of a KΡC-2-producing Pseudomonas putida isolate (PP36) in Brazil. The PP36 isolate was resistant to all the antimicrobials tested except polymyxin B. In addition to the discovered bla(KPC-2) gene, genetic analysis showed the presence of a class 1 integron containing the dhfrXVb gene and the new allele arr-6, which codes for resistance to rifampin. These elements were found in an IncFI 65-kb plasmid.
authors.affiliation: Universidade de Pernambuco, Recife, Pernambuco, Brazil.
authors.forename: Anna C S
authors.initials: AC
authors.lastname: Almeida
authors.forename: Marinalda A
authors.initials: MA
authors.lastname: Vilela
authors.forename: Felipe L S
authors.initials: FL
authors.lastname: Cavalcanti
authors.forename: Willames M B S
authors.initials: WM
authors.lastname: Martins
authors.forename: Marcos A
authors.initials: MA
authors.lastname: Morais
authors.forename: Marcia M C
authors.initials: MM
authors.lastname: Morais
mesh_terms: D000483:Alleles; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001938:Brazil; D002051:Burkitt Lymphoma / Q000150:complications / Q000188:drug therapy; D002648:Child; D006801:Humans; D032023:Integrons / Q000235:genetics; D008297:Male; D000077731:Meropenem; D008826:Microbial Sensitivity Tests; D008969:Molecular Sequence Data; D010957:Plasmids / Q000235:genetics; D016133:Polymerase Chain Reaction; D011552:Pseudomonas Infections / Q000188:drug therapy / Q000382:microbiology; D016958:Pseudomonas putida / Q000235:genetics / Q000378:metabolism*; D013845:Thienamycins / Q000627:therapeutic use; D001618:beta-Lactamases / Q000096:biosynthesis* / Q000235:genetics
chemical_list: D000900:Anti-Bacterial Agents; D013845:Thienamycins; C491478:beta-lactamase KPC-2; D001618:beta-Lactamases; D000077731:Meropenem