title: Changes in health-related quality of life 1 year following strabismus surgery.
abstract: OBJECTIVE
  To report changes in health-related quality of life (HRQOL) 1 year following strabismus surgery.
  
  
  METHODS
  Retrospective cohort study.
  
  
  METHODS
  Seventy-three adults undergoing strabismus surgery in a single clinical practice completed the Adult Strabismus-20 (AS-20) HRQOL questionnaire preoperatively and at 6 weeks and 1 year postoperatively. All included adults were successfully aligned at 6 weeks postoperatively. Success was defined based on clinical criteria. Change in AS-20 psychosocial and function scores was evaluated as: 1) difference in scores between 6 weeks and 1 year postoperatively and 2) proportions exceeding previously published limits of agreement at 6 weeks and 1 year.
  
  
  RESULTS
  For patients successfully aligned at both 6 weeks and 1 year (n=51), further improvement in median scores was seen from 6 weeks to 1 year for both the psychosocial scale (83.8 vs 93.8; P<.0001) and the function scale (72.5 vs 77.5; P=.007). Also, a greater proportion exceeded limits of agreement at 1 year than at 6 weeks (psychosocial: 48% vs 30%; P=.007, function: 67% vs 51%; P=.01). For patients who became partial success (n=18) or failure (n=4) at 1 year there was a numerical decrease in scores at 1 year.
  
  
  CONCLUSIONS
  Adult strabismus patients who remain successfully aligned show continued improvement in both psychosocial and function scores from 6 weeks to 1 year postoperatively, indicating that improvement in HRQOL is long-lasting. Evaluation of HRQOL should be considered when reporting strabismus surgery outcomes in clinical trials, and may prove helpful in assessing outcomes in clinical practice.
authors.affiliation: Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota 55905, USA.
authors.forename: Sarah R
authors.initials: SR
authors.lastname: Hatt
authors.forename: David A
authors.initials: DA
authors.lastname: Leske
authors.forename: Laura
authors.initials: L
authors.lastname: Liebermann
authors.forename: Jonathan M
authors.initials: JM
authors.lastname: Holmes
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004172:Diplopia / Q000503:physiopathology; D005260:Female; D006302:Health Services Research; D006304:Health Status; D006801:Humans; D008297:Male; D008875:Middle Aged; D009801:Oculomotor Muscles / Q000503:physiopathology / Q000601:surgery*; D013508:Ophthalmologic Surgical Procedures; D011788:Quality of Life; D012189:Retrospective Studies; D018434:Sickness Impact Profile; D013285:Strabismus / Q000503:physiopathology / Q000601:surgery*; D011795:Surveys and Questionnaires; D015348:Vision, Binocular / Q000502:physiology; D055815:Young Adult