title: Versatile synthesis of isocoumarins and α-pyrones by ruthenium-catalyzed oxidative C-H/O-H bond cleavages.
abstract: An inexpensive cationic ruthenium(II) catalyst enabled the expedient synthesis of isocoumarins through oxidative annulations of alkynes by benzoic acids. This C-H/O-H bond functionalization process also proved applicable to the preparation of α-pyrones and was shown to proceed by rate-limiting C-H bond ruthenation.
authors.affiliation: Institut für Organische und Biomolekulare Chemie, Georg-August-Universität, Tammannstrasse 2, 37077 Göttingen, Germany. Lutz.Ackermann@chemie.uni-goettingen.de
authors.forename: Lutz
authors.initials: L
authors.lastname: Ackermann
authors.forename: Jola
authors.initials: J
authors.lastname: Pospech
authors.forename: Karolina
authors.initials: K
authors.lastname: Graczyk
authors.forename: Karsten
authors.initials: K
authors.lastname: Rauch
mesh_terms: D002384:Catalysis; D049934:Isocoumarins / Q000138:chemical synthesis*; D015394:Molecular Structure; D010084:Oxidation-Reduction; D011753:Pyrones / Q000138:chemical synthesis*; D012428:Ruthenium / Q000737:chemistry*
chemical_list: D049934:Isocoumarins; D011753:Pyrones; D012428:Ruthenium