title: [Breast implants and health alert PIP: experience of the regional cancer center of Lille].
abstract: BACKGROUND
  On March 30, 2010, Afssaps issued a health alert concerning breast implants brand PIP, after identifying a rupture rate higher than for other manufacturers. This alert asking the recall of all concerned patients with, according to the clinical examination, ultrasound and the desire of the patient, the possibility of explantation. We focus on PIP implanted in Oscar-Lambret center in Lille.
  
  
  METHODS
  A retrospective study on all patients carrying breast prosthesis PIP implanted in the Oscar-Lambret center. We are interested in the rate of patients who chose clinical and ultrasound monotoring, explantation rates, and prosthetic rupture.
  
  
  RESULTS
  Thirty-three PIP (in 31 patients) have been implanted in the center between May 2, 2006 and March 9, 2010. The mean age of implants was 15.35 months. We realized eight explants, and found three intracapsular rupture. Two of three rupture were symptomatic.
  
  
  CONCLUSIONS
  The majority of patients chose surveillance. Our short series does not give precise information about their risk of prosthetic failure, a national register should be established. The literature illustrates the low sensitivity of ultrasonography in the diagnosis of intracapsular rupture and the superiority of MRI. In the context of a health alert, could we propose a monitoring tool implant breast MRI in order to minimize the rate of patients carrying a ruptured implant (false negative).
authors.affiliation: Centre Oscar-Lambret, département de sénologie, 3, rue Frédéric-Combemale, 59020 Lille Cedex, France. macarillon@hotmail.fr
authors.forename: Marie-Astrid
authors.initials: MA
authors.lastname: Carillon
authors.forename: Sylvia
authors.initials: S
authors.lastname: Giard
authors.forename: Virginie
authors.initials: V
authors.lastname: Emmanuelli
authors.forename: Jean-Louis
authors.initials: JL
authors.lastname: Houpeau
authors.forename: Luc
authors.initials: L
authors.lastname: Ceugnart
authors.forename: Marie-Pierre
authors.initials: MP
authors.lastname: Chauvet
mesh_terms: D018427:Breast Implants / Q000009:adverse effects*; D002173:Cancer Care Facilities; D020878:Device Removal / Q000706:statistics & numerical data; D005260:Female; D005602:France; D006801:Humans; D057910:Implant Capsular Contracture / Q000175:diagnosis; D008279:Magnetic Resonance Imaging / Q000592:standards; D016462:Mammaplasty / Q000295:instrumentation; D008875:Middle Aged; D011475:Prosthesis Failure; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D020034:Silicone Gels; D016217:Ultrasonography, Mammary / Q000592:standards
chemical_list: D020034:Silicone Gels