title: [The diagnostics of arrhythmogenic right ventricular dysplasia by an endomiocardial biopsy and the role of viruses in the pathogenesis of disease].
abstract: The comparative histologic, morphometric and immunohistochemical investigation of a right ventricular myocardium from 3 groups of patients has been carried out. The first group has included 12 patients with an arrythmogenic right ventricular dysplasia (ARVD) confirmed by an endomyocardial biopsy. The second group has consisted of 7 healthy people died a violent death. The third group has included 7 patients with a chronic alcoholism died from an acute alcoholic intoxication. The patients with ARVD and a chronic alcoholism have had an evident adiposis, a moderate fibrosis, and muscle atrophy with only 65% of cardiac hystiocytes. The patients with a chronic alcoholism have had only dystonia of intramural arteries. The cardiac hystiocytes of patients with ARVD have infected by enteroviruses (100%), parvoviruses B19 (58%), adenoviruses (25%), and hepatitis virus C (16%). 83% of observations have had a mixed viral infections.
authors.forename: L B
authors.initials: LB
authors.lastname: Mitrofanova
authors.forename: O V
authors.initials: OV
authors.lastname: Beshchuk
authors.forename: E Iu
authors.initials: EIu
authors.lastname: Naumova
mesh_terms: D000328:Adult; D000437:Alcoholism / Q000150:complications / Q000473:pathology / Q000821:virology; D001145:Arrhythmias, Cardiac / Q000473:pathology / Q000821:virology; D001706:Biopsy; D002310:Cardiomyopathy, Alcoholic / Q000473:pathology / Q000821:virology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009206:Myocardium / Q000473:pathology; D032383:Myocytes, Cardiac / Q000473:pathology / Q000821:virology; D014777:Virus Diseases / Q000473:pathology / Q000821:virology