title: Autoimmunity in X-linked agammaglobulinemia: Kawasaki disease and review of the literature.
abstract: Although autoimmunity phenotype is surprisingly common in patients with different types of primary antibody deficiency, it is much less frequent in X-linked agammaglobulinemia (XLA). Herein, we report on a 15-month-old boy with XLA who also suffered from Kawasaki disease. The current case presentation is the first report of an association between Kawasaki disease and XLA. XLA could be considered as a special opportunity to understand autoimmunity in the near absence of immunoglobulins.
authors.affiliation: Research Center for Immunodeficiencies, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Nasrin
authors.initials: N
authors.lastname: Behniafard
authors.forename: Asghar
authors.initials: A
authors.lastname: Aghamohammadi
authors.forename: Hassan
authors.initials: H
authors.lastname: Abolhassani
authors.forename: Sarvenaz
authors.initials: S
authors.lastname: Pourjabbar
authors.forename: Farah
authors.initials: F
authors.lastname: Sabouni
authors.forename: Nima
authors.initials: N
authors.lastname: Rezaei
mesh_terms: D000293:Adolescent; D000361:Agammaglobulinemia / Q000150:complications / Q000188:drug therapy / Q000235:genetics / Q000276:immunology / Q000473:pathology; D040181:Genetic Diseases, X-Linked / Q000150:complications / Q000188:drug therapy / Q000235:genetics / Q000276:immunology / Q000473:pathology; D006801:Humans; D008297:Male; D009080:Mucocutaneous Lymph Node Syndrome / Q000150:complications / Q000235:genetics / Q000276:immunology / Q000473:pathology