title: Enantioseparation of 1-arylethanols via a supramolecular chiral host consisting of N-(2-naphthoyl)-L-aspartic acid and an achiral diamine.
abstract: A supramolecular chiral host consisting of N-(2-naphthoyl)-L-aspartic acid (L-1) and meso-1,2-diphenylethylenediamine (2) is effective in enantioseparation of 1-arylethanols (up to 96% ee with 100% inclusion ratio). Here we report three different methods to prepare the inclusion crystals and discuss the chiral recognition mechanism on the basis of X-ray crystallography results.
authors.affiliation: Graduate School of Science and Engineering, Saitama University, 255 Shimo-Okubo, Sakura-ku, Saitama 338-8570, Japan. kodama@mail.saitama-u.ac.jp
authors.forename: Koichi
authors.initials: K
authors.lastname: Kodama
authors.forename: Ayaka
authors.initials: A
authors.lastname: Kanno
authors.forename: Eriko
authors.initials: E
authors.lastname: Sekine
authors.forename: Takuji
authors.initials: T
authors.lastname: Hirose
mesh_terms: D001224:Aspartic Acid / Q000031:analogs & derivatives* / Q000737:chemistry; D018360:Crystallography, X-Ray; D003959:Diamines / Q000737:chemistry*; D000431:Ethanol / Q000737:chemistry* / Q000302:isolation & purification; D008958:Models, Molecular; D015394:Molecular Structure; D009281:Naphthalenes / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D003959:Diamines; D009281:Naphthalenes; D001224:Aspartic Acid; D000431:Ethanol