title: An urn based covariate adjusted response adaptive allocation design.
abstract: An urn based covariate adjusted response adaptive allocation design with dichotomous responses is proposed incorporating the ordered nature of the covariate. The allocation procedure is assessed both numerically and theoretically. The performance of the allocation design is also investigated in a relevant hypothetical clinical trial.
authors.affiliation: Department of Statistics, University of Calcutta, Kolkata, India. ubandyopadhyay08@gmail.com
authors.forename: Uttam
authors.initials: U
authors.lastname: Bandyopadhyay
authors.forename: Rahul
authors.initials: R
authors.lastname: Bhattacharya
mesh_terms: D056808:Biostatistics / Q000379:methods*; D006801:Humans; D006973:Hypertension / Q000503:physiopathology / Q000628:therapy; D015233:Models, Statistical; D016032:Randomized Controlled Trials as Topic / Q000706:statistics & numerical data*