title: Renal transitional-cell carcinoma in two cats with chronic kidney disease.
abstract: Two 12-year-old cats were diagnosed with chronic kidney disease (CKD) based on physical examination, clinicopathologic data and, in one case, abdominal ultrasound findings. Approximately 1 year after the initial diagnosis of CKD both cats developed renal transitional cell carcinoma (TCC)--bilateral in one cat. Based on post-mortem examination, one cat had no evidence of metastasis and the other had metastasis to the large intestine, heart and lungs. This is the first report of de novo bilateral renal TCC in a cat, as well as the first report of renal TCC developing in cats with previous history of confirmed CKD.
authors.affiliation: Department of Veterinary Clinical Sciences, Center for Veterinary Health Sciences, Oklahoma State University, Stillwater, OK 74078, USA. andrew.hanzlicek@okstate.edu
authors.forename: Andrew S
authors.initials: AS
authors.lastname: Hanzlicek
authors.forename: Chanran
authors.initials: C
authors.lastname: Ganta
authors.forename: Carl B
authors.initials: CB
authors.lastname: Myers
authors.forename: Gregory F
authors.initials: GF
authors.lastname: Grauer
mesh_terms: D000818:Animals; D002292:Carcinoma, Renal Cell / Q000150:complications / Q000473:pathology / Q000662:veterinary*; D002295:Carcinoma, Transitional Cell / Q000150:complications / Q000473:pathology / Q000662:veterinary*; D002371:Cat Diseases / Q000175:diagnosis* / Q000473:pathology; D002415:Cats; D017809:Fatal Outcome; D006338:Heart Neoplasms / Q000556:secondary / Q000662:veterinary; D007414:Intestinal Neoplasms / Q000556:secondary / Q000662:veterinary; D007676:Kidney Failure, Chronic / Q000150:complications / Q000175:diagnosis / Q000662:veterinary*; D008175:Lung Neoplasms / Q000556:secondary / Q000662:veterinary; D008297:Male