title: Comment on "Dynamics of dpp signaling and proliferation control".
abstract: Wartlick et al. (Research Articles, 4 March 2011, p. 1154) reported that growth rates in the Drosophila wing disc correlate with increasing Dpp signaling levels, suggesting that the rate of Dpp increase determines the cell-cycle length. Contradicting their model, we found that cells in which the increase of Dpp signaling levels was genetically abrogated grew at rates comparable to those of wild-type cells.
authors.affiliation: Institute of Molecular Life Sciences, University of Zurich, Zurich, Switzerland.
authors.forename: Gerald
authors.initials: G
authors.lastname: Schwank
authors.forename: Schu-Fee
authors.initials: SF
authors.lastname: Yang
authors.forename: Simon
authors.initials: S
authors.lastname: Restrepo
authors.forename: Konrad
authors.initials: K
authors.lastname: Basler
mesh_terms: D000818:Animals; D049109:Cell Proliferation; D029721:Drosophila Proteins / Q000378:metabolism*; D004331:Drosophila melanogaster / Q000254:growth & development* / Q000378:metabolism*; D036341:Intercellular Signaling Peptides and Proteins / Q000378:metabolism*; D015398:Signal Transduction; D014921:Wings, Animal / Q000254:growth & development* / Q000378:metabolism*
chemical_list: D029721:Drosophila Proteins; D036341:Intercellular Signaling Peptides and Proteins