title: [Placental vascular lesion as cause of IUGR and nonimmune fetal hydrops in twin pregnancy].
abstract: Placenta vascular lesions are a group of distinct yet related entities that include chorangiomas and diffuse multifocal chorangiomatosis. Chorangioma is an expansive nodular lesion with an incidence of about 1%. Diffuse multifocal chorangiomatosis is rare (0.2%) and mostly seen in placentas before the 32nd gestational week. The authors present a case of a monochorionic/biamniotic twin pregnancy, in which, at the 26th gestational week, one fetus developed intrauterine growth restriction (IUGR), hydrops, and anemia associated with a tumor of the placenta with increased vascularization in the Doppler study. Pathological examination of the placenta diagnosed diffuse multifocal chorangiomatosis. This rare case report of diffuse multifocal chorangiomatosis with prenatal manifestations resembling those of a chorangioma proves that prenatal ultrasound detection of a placenta tumor, with increased vascularization at Doppler study, must raise other diagnostic possibilities beside chorangioma.
authors.affiliation: Maternidade Bissaya-Barreto, Coimbra, Portugal.
authors.forename: Nuno Ricardo
authors.initials: NR
authors.lastname: Gonçalves Baptista Pereira
authors.forename: Miguel Pedro
authors.initials: MP
authors.lastname: da Rocha Branco
authors.forename: Maria Isabel
authors.initials: MI
authors.lastname: Santos Silva
authors.forename: Eulália Maria
authors.initials: EM
authors.lastname: Bento Galhano
authors.forename: Raquel Maria
authors.initials: RM
authors.lastname: Pereira Ortins Pina
authors.forename: Luís Filipe
authors.initials: LF
authors.lastname: Costa Dias de Matos
authors.forename: José Agostinho
authors.initials: JA
authors.lastname: Valentim Barros de Mesquita
mesh_terms: D000328:Adult; D005260:Female; D005317:Fetal Growth Retardation / Q000209:etiology*; D006801:Humans; D015160:Hydrops Fetalis / Q000209:etiology*; D010920:Placenta / Q000098:blood supply*; D010922:Placenta Diseases; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular; D059285:Pregnancy, Twin; D014652:Vascular Diseases