title: Primary cutaneous angiosarcoma of the breast after breast trauma.
abstract: Primary angiosarcoma of the breast is a rare malignant tumor. We report a case of breast primary cutaneous angiosarcoma in a patient with a strong family history of malignancy. For definitive diagnosis, a tissue biopsy is needed, with immunostaining for the presence of blood vessel endothelial markers CD31 and CD34. Total mastectomy is the preferred method of surgical treatment. Chemotherapy has not been shown to increase overall survival, but in some instances it may improve local control and disease-free survival. Surgery combined with radiation may increase local control, but patients at high risk of recurrence may benefit from adjuvant treatment as well. We discuss the potential benefits from various treatments for primary cutaneous breast angiosarcoma.
authors.affiliation: Departments of Oncology (Cao, Panos, Mennel) and Pathology (Graham), Baylor Charles A. Sammons Cancer Center and Baylor University Medical Center at Dallas; and Skin Cancer Consultants, Dallas, Texas (Parker).
authors.forename: Ying
authors.initials: Y
authors.lastname: Cao
authors.forename: Laura
authors.initials: L
authors.lastname: Panos
authors.forename: Robbie L
authors.initials: RL
authors.lastname: Graham
authors.forename: Thornwell H
authors.initials: TH
authors.lastname: Parker
authors.forename: Robert
authors.initials: R
authors.lastname: Mennel