title: [Syphilis in pregnancy].
abstract: Inadequately treated, maternal syphilis often results in serious sequels for the fetus/newborn. Poor prenatal care is a major risk factor for the development of congenital syphilis.
  
  
  OBJECTIVE
  To determine the results of syphilis screening and followup programs on the incidence of syphilis in pregnant women and their offspring.
  
  
  METHODS
  Data on the incidence of syphilis, new syphilis cases, pregnant women diagnosed with syphilis and newborns confirmed with congenital syphilis in the Iasi district in the interval 2000-2009 have been collected.
  
  
  RESULTS
  In the interval 2000-2010 the incidence of syphilis in the lasi district has decreased from 47.5/100,000 inhabitant in 2001 to 10.5% in 2009, and the new syphilis cases from 627 in 2001 to 87 in 2009. The highest number of pregnant women infected with syphilis was recorded in 2006 (74), and the lowest in 2010 (26). Most newborns confirmed with congenital syphilis were also recorded in 2006 (6), in the interval 2008-2010 no such case being recorded.
  
  
  CONCLUSIONS
  All pregnant women have to be subjected to a serological screening test for syphilis at least twice during pregnancy: early during the first trimester and after week 28. Moreover, the women at risk for syphilis have to be examined serologically at delivery. All women who miscarry after 20 weeks of gestation have to be tested for syphilis. All newborns whose mothers' serological status for syphilis was not determined during pregnancy have to be tested before discharge.
authors.affiliation: Universităţii de Medicină şi Farmacie "Gr. T. Popa" Iaşi.
authors.forename: M
authors.initials: M
authors.lastname: Daoud
authors.forename: Elena
authors.initials: E
authors.lastname: Duca
authors.forename: Zenaida
authors.initials: Z
authors.lastname: Petrescu
mesh_terms: D000328:Adult; D000465:Algorithms; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D018445:Infectious Disease Transmission, Vertical; D008403:Mass Screening; D008499:Medical Records; D010401:Penicillin G Benzathine / Q000627:therapeutic use; D011159:Population Surveillance; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology / Q000517:prevention & control; D011256:Pregnancy Outcome; D011295:Prenatal Care; D018570:Risk Assessment; D012307:Risk Factors; D012383:Romania / Q000453:epidemiology; D013587:Syphilis / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology* / Q000517:prevention & control / Q000635:transmission; D013588:Syphilis Serodiagnosis / Q000379:methods; D013590:Syphilis, Congenital / Q000188:drug therapy / Q000453:epidemiology; D016896:Treatment Outcome
chemical_list: D010401:Penicillin G Benzathine