Development of a pixelated GSO gamma camera system with tungsten parallel hole collimator for single photon imaging.
OBJECTIVE
In small animal imaging using a single photon emitting radionuclide, a high resolution gamma camera is required. Recently, position sensitive photomultiplier tubes (PSPMTs) with high quantum efficiency have been developed. By combining these with nonhygroscopic scintillators with a relatively low light output, a high resolution gamma camera can become useful for low energy gamma photons. Therefore, the authors developed a gamma camera by combining a pixelated Ce-doped Gd(2)SiO(5) (GSO) block with a high quantum efficiency PSPMT.


METHODS
GSO was selected for the scintillator, because it is not hygroscopic and does not contain any natural radioactivity. An array of 1.9 mm × 1.9 mm × 7 mm individual GSO crystal elements was constructed. These GSOs were combined with a 0.1-mm thick reflector to form a 22 × 22 matrix and optically coupled to a high quantum efficiency PSPMT (H8500C-100 MOD8). The GSO gamma camera was encased in a tungsten gamma-ray shield with tungsten pixelated parallel hole collimator, and the basic performance was measured for Co-57 gamma photons (122 keV).


RESULTS
In a two-dimensional position histogram, all pixels were clearly resolved. The energy resolution was ∼15% FWHM. With the 20-mm thick tungsten pixelated collimator, the spatial resolution was 4.4-mm FWHM 40 mm from the collimator surface, and the sensitivity was ∼0.05%. Phantom and small animal images were successfully obtained with our developed gamma camera.


CONCLUSIONS
These results confirmed that the developed pixelated GSO gamma camera has potential as an effective instrument for low energy gamma photon imaging.
Kobe City College of Technology, Nishi-ku, Kobe, Japan.
S
S
Yamamoto
H
H
Watabe
Y
Y
Kanai
E
E
Shimosegawa
J
J
Hatazawa
D000818:Animals; D004867:Equipment Design; D019544:Equipment Failure Analysis; D015902:Gamma Cameras / Q000662:veterinary*; D007089:Image Enhancement / Q000295:instrumentation*; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012815:Signal Processing, Computer-Assisted / Q000295:instrumentation*; D015899:Tomography, Emission-Computed, Single-Photon / Q000295:instrumentation* / Q000662:veterinary*; D051598:Whole Body Imaging / Q000295:instrumentation* / Q000662:veterinary*