Asymptomatic urinary anomalies, hematuria and proteinuria, in patients with inflammatory bowel disease. Preliminary study.
The study assesses the presence of asymptomatic urinary anomalies in patients with inflammatory bowel disease. Asymptomatic urinary anomalies are mainly due to glomerular nephritis, they being one of the forms of its manifestation, together with chronic nephrotic and nephritic syndromes. We identified urinary anomalies in 18 patients (20%) with bowel inflammatory disease that consisted of haematuria in 8 (9%) patients, isolated proteinuria in 5 (6%) patients and haematuria associated with proteinuria in 5 (6%) patients. Asymptomatic urinary anomalies were more frequent in patients with the Crohn disease than in those with ulcerative colitis. We identified RFG under 60ml/min in 4 patients with asymptomatic urinary anomalies. It is very easy to evaluate asymptomatic urinary anomalies with dipstick. This method is also required in current practice for patients with urinary anomalies for identifying the glomerular disease that might have caused them. One must take into consideration differential diagnosis with other diseases that can manifest themselves with proteinuria or isolated proteinuria. One must also take into account the fact that urinary anomalies may also be related to administration of 5-aminosalicylates.
Nephrology Department, University of Medicine and Pharmacy Timişoara, Romania. s_velciov@yahoo.com
Silvia
S
Velciov
Gh
G
Gluhovschi
I
I
Sporea
Virginia
V
Trandafirescu
Ligia
L
Petrica
Gh
G
Bozdog
Cristina
C
Gluhovschi
F
F
Bob
Florica
F
Gădălean
Roxana
R
Buzaş
Maria
M
Bobu
L
L
Voicu
D000328:Adult; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000009:adverse effects*; D003093:Colitis, Ulcerative / Q000188:drug therapy; D003424:Crohn Disease / Q000188:drug therapy; D003937:Diagnosis, Differential; D005260:Female; D005921:Glomerulonephritis / Q000139:chemically induced; D006417:Hematuria / Q000139:chemically induced*; D006801:Humans; D015994:Incidence; D015212:Inflammatory Bowel Diseases / Q000188:drug therapy*; D007674:Kidney Diseases / Q000139:chemically induced* / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology; D007676:Kidney Failure, Chronic / Q000139:chemically induced; D007678:Kidney Glomerulus / Q000187:drug effects; D008297:Male; D019804:Mesalamine / Q000008:administration & dosage / Q000009:adverse effects*; D008875:Middle Aged; D009404:Nephrotic Syndrome / Q000139:chemically induced; D011507:Proteinuria / Q000139:chemically induced*; D012189:Retrospective Studies; D012383:Romania / Q000453:epidemiology; D012494:Sampling Studies; D012720:Severity of Illness Index
D000894:Anti-Inflammatory Agents, Non-Steroidal; D019804:Mesalamine