A new paradigm in the treatment of kerions: treat the inflammation.
Kerions result from a massive delayed-type hypersensitivity reaction to a dermatophyte. Treatment traditionally has been directed primarily toward the dermatophyte. The authors propose, however, that inflammation should be the initial target oftreatment. Clinical findings and treatment outcomes for two patients with kerions, treated with short courses of anti-inflammatory agents, are presented. Earlier studies showing minimal effects with corticosteroid treatment of kerions may have had design flaws. The anti-inflammatory treatment of kerions is both safe and effective and permits the duration of therapy to be shortened dramatically.
Department of Dermatology, Drexel University College of Medicine, Philadelphia, PA 19107, USA.
Sarah E
SE
Dolder
Brendan J
BJ
O'Neill
Meghan M
MM
O'Brien
Amy S
AS
Ross
Robert A
RA
Allen
Herbert B
HB
Allen
D000893:Anti-Inflammatory Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D003883:Arthrodermataceae / Q000302:isolation & purification; D002648:Child; D003881:Dermatomycoses / Q000188:drug therapy* / Q000382:microbiology / Q000473:pathology; D005938:Glucocorticoids / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use; D006801:Humans; D007249:Inflammation / Q000188:drug therapy* / Q000382:microbiology; D008297:Male; D013997:Time Factors; D016896:Treatment Outcome
D000893:Anti-Inflammatory Agents; D005938:Glucocorticoids