Iterative asymmetric allylic substitutions: syn- and anti-1,2-diols through catalyst control.
A copper-catalyzed asymmetric allylic boronation (AAB) gives access to syn- and anti-1,2-diols. The method facilitates an iterative strategy for the preparation of polyols, such as the fully differentiated L-ribo-tetrol and protected D-arabino-tetrol. P=protecting group.
Department of Chemistry & Biochemistry, Florida State University, Tallahassee, 32306-4390, USA.
Jin Kyoon
JK
Park
D Tyler
DT
McQuade
D001896:Boron Compounds / Q000737:chemistry; D002384:Catalysis; D003300:Copper / Q000737:chemistry; D011108:Polymers / Q000737:chemistry*; D013237:Stereoisomerism
D001896:Boron Compounds; D011108:Polymers; C024617:polyol; D003300:Copper