Design and self-assembly of a leucine-enkephalin analogue in different nanostructures: application of nanovesicles.
An opioid (leucine-enkephalin) conformational analogue forms diverse nanostructures such as vesicles, tubes, and organogels through self-assembly. The nanovesicles encapsulate the natural hydrophobic drug curcumin and allow the controlled release through cation-generated porogens in membrane mimetic solvent.
Department of Chemistry, University of Calcutta, 92, A. P. C. Road, Kolkata-700 009, India.
Pradyot
P
Koley
Anindita
A
Gayen
Michael G B
MG
Drew
Chaitali
C
Mukhopadhyay
Animesh
A
Pramanik
D003474:Curcumin / Q000008:administration & dosage / Q000737:chemistry; D004337:Drug Carriers / Q000737:chemistry; D004743:Enkephalin, Leucine / Q000737:chemistry*; D018625:Microscopy, Atomic Force; D008855:Microscopy, Electron, Scanning; D046529:Microscopy, Electron, Transmission; D008856:Microscopy, Fluorescence; D049329:Nanostructures / Q000737:chemistry* / Q000648:ultrastructure; D036103:Nanotechnology / Q000379:methods*
D004337:Drug Carriers; D004743:Enkephalin, Leucine; D003474:Curcumin