Metastatic hepatocellular carcinoma presenting as facial nerve palsy and facial pain.
Facial nerve palsy due to temporal bone metastasis of hepatocellular carcinoma (HCC) has rarely been reported. We experienced a rare case of temporal bone metastasis of HCC that initially presented as facial nerve palsy and was diagnosed by surgical biopsy. This patient also discovered for the first time that he had chronic hepatitis B and C infections due to this facial nerve palsy. Radiation therapy greatly relieved the facial pain and facial nerve palsy. This report suggests that hepatologists should consider metastatic HCC as a rare but possible cause of new-onset cranial neuropathy in patients with chronic viral hepatitis.
Departement of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea. dr1004@snu.ac.kr
Jong In
JI
Yang
Jung Mook
JM
Kang
Hee Jin
HJ
Byun
Go Eun
GE
Chung
Jeong Yoon
JY
Yim
Min Jung
MJ
Park
Jeong Hoon
JH
Lee
Jung Hwan
JH
Yoon
Hyo Suk
HS
Lee
D006528:Carcinoma, Hepatocellular / Q000150:complications / Q000473:pathology*; D005155:Facial Nerve Diseases / Q000175:diagnosis / Q000209:etiology; D005157:Facial Pain / Q000209:etiology; D005158:Facial Paralysis / Q000175:diagnosis / Q000209:etiology; D019694:Hepatitis B, Chronic / Q000175:diagnosis; D019698:Hepatitis C, Chronic / Q000175:diagnosis; D006801:Humans; D007150:Immunohistochemistry; D008113:Liver Neoplasms / Q000150:complications / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D049268:Positron-Emission Tomography; D012888:Skull Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000556:secondary; D014057:Tomography, X-Ray Computed