Early-stage malignant peripheral nerve sheath tumour arising from a solitary neurofibroma.
We report a case of early-stage malignant peripheral nerve sheath tumour (MPNST) found in a solitary neurofibroma, and its CT and MRI findings. A 19-year-old male with no known history of a neurofibromatosis presented with a painless swelling in the left forearm. CT and MRI scans showed a well-circumscribed, intermuscular mass, which was 6.0 cm in diameter and contained a strongly enhanced 1.0 cm nodular structure with surrounding oedema. Peripheral nerve continuity with the mass was not seen. Histological evaluation proved the nodular structure was an MPNST component completely surrounded by neurofibroma. Following an excisional biopsy with wide margins, the patient was followed up for a year without treatment and no recurrence was observed.
Department of Diagnostic, Ehime University Graduate School of Medicine, Shitsukawa, Toon city, Japan. neneth@m.ehime-u.ac.jp
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Hyodo
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Sugawara
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Sakayama
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Kito
D005542:Forearm / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D018317:Nerve Sheath Neoplasms / Q000175:diagnosis* / Q000601:surgery; D009455:Neurofibroma / Q000175:diagnosis / Q000601:surgery; D012983:Soft Tissue Neoplasms / Q000175:diagnosis* / Q000601:surgery; D014057:Tomography, X-Ray Computed; D055815:Young Adult