Pathophysiology of overactive bladder.
Overactive bladder (OAB) is a common disorder that negatively affects the quality of life of our patients and carries a large socioeconomic burden. According to the International Continence Society, it is characterized as urinary urgency, with or without urge incontinence, usually, with frequency and nocturia in the absence of causative infection. The pathophysiology of this disease entity varies between neurogenic, myogenic, or idiopathic factors. This paper provides a review of the contemporary theories behind the pathophysiology of OAB.
Toronto Western Hospital, Toronto, ON, M5T2S8, Canada. drmaibanakher@hotmail.com
Mai A
MA
Banakhar
Tariq F
TF
Al-Shaiji
Magdy M
MM
Hassouna
D000344:Afferent Pathways / Q000503:physiopathology; D000375:Aging / Q000502:physiology; D005260:Female; D006801:Humans; D007511:Ischemia / Q000503:physiopathology; D008297:Male; D011788:Quality of Life / Q000523:psychology; D012727:Sex Characteristics; D001743:Urinary Bladder / Q000098:blood supply / Q000294:innervation / Q000503:physiopathology*; D053201:Urinary Bladder, Overactive / Q000209:etiology* / Q000503:physiopathology* / Q000523:psychology