Therapeutic effectiveness of a new enzymatic bleaching dentifrice.
BACKGROUND
Research into bleaching focuses on new products in order to minimize undesirable effects. This study evaluated the bleaching effectiveness of a new enzymatic-activated dentifrice.


METHODS
A total of 20 volunteers were bleached with a dentifrice containing 5% lactoperoxidase and 3% carbamide peroxide applied three times a day for two minutes over 21 days. Color was recorded before and after the treatment using a spectrophotometer. CIELAB differences were calculated before and after treatment using the paired t test (P < 0.05).


RESULTS
Lightness was significantly higher after treatment (P < 0.001), ΔE was 5.14. The maxillary central incisors showed greater lightness than the laterals and canines, both before and after treatment, and a greater tendency towards green and blue; the same occurred in the mandibular central incisors in comparison to the canines and laterals.


CONCLUSIONS
The use of brush-applied enzyme-activated carbamide peroxide at low concentrations with short exposure time is effective for whitening teeth.


CONCLUSIONS
Enzymatic dental bleaching is able to increase the efficiency of low concentration peroxides, reducing the potential risk of peroxides on oral tissues.
Universitat de Valencia, Valencia, Spain.
Leopaldo
L
Forner
José
J
Amengual
Carmen
C
Liena
Pere
P
Riutord
D000328:Adult; D000077463:Carbamide Peroxide; D003116:Color; D003481:Cuspid / Q000187:drug effects; D003802:Dentifrices / Q000627:therapeutic use*; D005500:Follow-Up Studies; D006801:Humans; D007180:Incisor / Q000187:drug effects; D007784:Lactoperoxidase / Q000627:therapeutic use*; D008875:Middle Aged; D010545:Peroxides / Q000627:therapeutic use*; D013053:Spectrophotometry; D013997:Time Factors; D014073:Tooth Bleaching / Q000379:methods; D058205:Tooth Bleaching Agents / Q000627:therapeutic use*; D014099:Toothbrushing / Q000295:instrumentation; D016896:Treatment Outcome; D014508:Urea / Q000031:analogs & derivatives* / Q000627:therapeutic use
D003802:Dentifrices; D010545:Peroxides; D058205:Tooth Bleaching Agents; D000077463:Carbamide Peroxide; D014508:Urea; D007784:Lactoperoxidase