A general and selective copper-catalyzed reduction of secondary amides.
In situ-generated cationic copper/pybox catalyst systems allow for the selective reduction of secondary amides into the corresponding amines under mild conditions. This novel protocol has a wide substrate scope and shows good functional group tolerance.
Leibniz-Institut fur Katalyse e. V., A.-Einstein-Str. 29a, Rostock, 18059, Germany.
Shoubhik
S
Das
Benoît
B
Join
Kathrin
K
Junge
Matthias
M
Beller