Twelve-month outcomes of the loozit randomized controlled trial: a community-based healthy lifestyle program for overweight and obese adolescents.
OBJECTIVE
To assess the outcomes of the Loozit adolescent weight management intervention and to evaluate the effect of additional therapeutic contact 12 months into the program.


METHODS
A 24-month, 2-arm randomized controlled trial. Results at 12 months are presented.


METHODS
Community health center and children's hospital in Sydney, Australia.


METHODS
A total of 151 overweight or obese 13- to 16-year-olds.


METHODS
In the first 2 months (phase 1), participants received 7 adolescent and parent weekly sessions focused on lifestyle modification. From 2 to 24 months (phase 2), adolescents attended booster sessions once every 3 months. During phase 2, adolescents randomized to the additional therapeutic contact arm also received telephone coaching and electronic communications once every 2 weeks.


METHODS
Baseline to 12-month changes in body mass index z score and waist to height ratio (primary outcomes) and changes in metabolic, psychosocial, and behavioral variables.


RESULTS
Of 151 randomized adolescents, 82.1% completed 12-month follow-up. Intent-to-treat analyses showed significant reductions in mean body mass index z score (-0.09; 95% CI, -0.12 to -0.06), waist to height ratio (-0.02; 95% CI, -0.03 to -0.01), total cholesterol level (-4 mg/dL; 95% CI, -8 to 0 mg/dL; to convert to millimoles per liter, multiply by 0.0259), and triglycerides level (geometric mean, -80 mg/dL; 95% CI, -88 to -71 mg/dL; to convert to millimoles per liter, multiply by 0.0113). Most psychosocial outcomes improved, including global self-worth, but there were few dietary, physical activity, or sedentary behavior changes. No difference was found in primary outcomes between participants who did or did not receive additional therapeutic contact.


CONCLUSIONS
The Loozit randomized controlled trial produced a significant but modest reduction in body mass index z score and improved psychosocial outcomes at 12 months. Supplementary telephone and electronic contact provided no additional benefit at 12 months. Trial Registration anzctr.org.au Identifier: 12606000175572.
University of Sydney Clinical School, The Children’s Hospital at Westmead, Australia.
Binh
B
Nguyen
Vanessa A
VA
Shrewsbury
Janice
J
O'Connor
Katharine S
KS
Steinbeck
Anthea
A
Lee
Andrew J
AJ
Hill
Smita
S
Shah
Michael R
MR
Kohn
Siranda
S
Torvaldsen
Louise A
LA
Baur
D000293:Adolescent; D000294:Adolescent Behavior; D001315:Australia; D001827:Body Height; D015992:Body Mass Index; D002784:Cholesterol / Q000097:blood; D015928:Cognitive Behavioral Therapy / Q000379:methods*; D003376:Counseling; D005260:Female; D015438:Health Behavior; D006801:Humans; D008019:Life Style; D008297:Male; D009765:Obesity / Q000523:psychology / Q000628:therapy*; D017063:Outcome Assessment, Health Care; D050177:Overweight / Q000523:psychology / Q000628:therapy*; D012649:Self Concept; D013689:Telephone; D014280:Triglycerides / Q000097:blood; D055105:Waist Circumference
D014280:Triglycerides; D002784:Cholesterol