Two new cyclopeptides and one new nonenolide from Xylaria sp. 101.
Two novel cyclopeptides, xylarotides A (1), and B (2), and one novel nonenolide, xylarolide (3), along with two known compounds, coriloxin (4), and 2-hydroxy-3-methoxy-5-methyl-p-benzoquinone (5) were isolated from the fungal strain Xylaria sp. 101. This strain was isolated from the fruiting body of Xylaria sp. collected in Gaoligong Mountain, Yunnan Province. The chemical structures were elucidated by spectroscopic analyses, including 1D- and 2D-NMR spectroscopic experiments, and on the basis of HR-Q-TOF mass spectrometry. Antibacterial assays of 1 - 3 were carried out; no effects on the growth of the tested bacteria and yeast were observed.
School of Pharmaceutical Sciences, Shandong University, Jinan, Shandong 250000, PR China.
Yao-Yao
YY
Li
Zhi-Yu
ZY
Hu
Yue-Mao
YM
Shen
D001419:Bacteria / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy; D010456:Peptides, Cyclic / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D013098:Xylariales / Q000737:chemistry*
D010456:Peptides, Cyclic; C571795:xylarotide A; C571796:xylarotide B