[Use of slow-release injections to administer  antipsychotic drugs].
Compliance is a major problem in connection with the use of antipsychotics.  Slow-release injections were therefore developed in the 1960s. As  a result of a substantial reduction of water solubility, the active  substance diffuses slowly from the injection site so that a therapeutic  serum concentration is assured throughout the period. New studies  show that this treatment can reduce the risk of patients requiring  hospitalisation and of psychotic relapses compared with the use  of tablets.
Senter for psykofarmakologi, Diakonhjemmet Sykehus, Norway. gudrun.hoiseth@diakonsyk.no
Gudrun
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Høiseth
Håvard
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Bentsen
D014150:Antipsychotic Agents / Q000008:administration & dosage* / Q000009:adverse effects; D003692:Delayed-Action Preparations / Q000008:administration & dosage* / Q000493:pharmacokinetics; D006801:Humans; D007267:Injections; D055118:Medication Adherence; D012559:Schizophrenia / Q000188:drug therapy
D014150:Antipsychotic Agents; D003692:Delayed-Action Preparations