The intravascular susceptibility effect and the underlying physiology of fMRI.
In this article, I will first give a brief account of my work at MGH on characterizing the intravascular susceptibility effect. Then I will describe studies into the underlying physiology of BOLD-fMRI which has become of interest to my group in the following decade. I will touch issues such as signal source of BOLD fMRI, capillary recruitment, the elusive initial dip and others.
Department of Neurology, Max Planck Institute & Clinic for Cognitive Neurology, Leipzig University, Leipzig, Germany. villringer@cbs.mpg.de
Arno
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Villringer
D001921:Brain / Q000098:blood supply* / Q000502:physiology; D001931:Brain Mapping / Q000266:history* / Q000379:methods; D002560:Cerebrovascular Circulation / Q000502:physiology*; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000266:history / Q000379:methods; D008279:Magnetic Resonance Imaging / Q000266:history* / Q000379:methods; D010100:Oxygen / Q000097:blood
D010100:Oxygen