An evolutionary perspective for contemporary psychiatric research.
Behaviour represents the ultimate output of the brain and is characterized by a high level of inter-individual variability. On the one hand, taking into account evolutionary history and adaptive significance of behavioural responses allows to design experimental protocols that improve both data quality and interpretation. On the other hand, a multilevel approach, which analyses factors ranging from the genetic set up to the socioeconomic status, leads to a more comprehensive and effective investigation of mechanisms underlying brain function. Exploitation of this approach in clinical studies may provide new strategies to more precisely investigate psychiatric disorders.
Reparto di Neuroscienze Comportamentali, Dipartimento di Biologia Cellulare e Neuroscienze, Istituto Superiore di Sanità, Roma. alleva@iss.it
Enrico
E
Alleva
Igor
I
Branchi
D000223:Adaptation, Psychological; D001519:Behavior; D005075:Biological Evolution; D035843:Biomedical Research; D001921:Brain / Q000502:physiology* / Q000503:physiopathology; D006801:Humans; D007175:Impulsive Behavior / Q000503:physiopathology; D001523:Mental Disorders / Q000503:physiopathology; D011570:Psychiatry