Medications in patients treated with therapeutic plasma exchange: prescription dosage, timing, and drug overdose.
Therapeutic plasma exchange (TPE) is an extracorporeal process commonly used in clinical medicine for the treatment of a variety of neurological, renal, hematological, dermatological, and other diseases. Inherent to the procedure, patients' plasma removal may lead to the extraction of drugs they are concurrently receiving. This review discusses the published literature assessing TPE's influence on different drug classes' disposition and, when applicable, sets forth management recommendations in cases where the drugs are used at the usual doses and in cases of drug overdose.
Department of Pharmacology and Toxicology, College of Osteopathic Medicine, Michigan State University, East Lansing, Michigan, USA.
Rami B
RB
Ibrahim
Rasheed A
RA
Balogun
D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D062787:Drug Overdose / Q000175:diagnosis / Q000401:mortality / Q000628:therapy*; D064420:Drug-Related Side Effects and Adverse Reactions; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D004364:Pharmaceutical Preparations / Q000008:administration & dosage; D010951:Plasma Exchange / Q000379:methods*; D010956:Plasmapheresis / Q000379:methods; D055553:Prescription Drugs / Q000008:administration & dosage / Q000009:adverse effects*; D018570:Risk Assessment; D015996:Survival Rate; D016896:Treatment Outcome
D004364:Pharmaceutical Preparations; D055553:Prescription Drugs