[Research progress of antitumor components from original animals of traditional Chinese medicine powder of Notarchus].
Powder of Notarchus is a traditional Chinese medicine originated from the eggs of various sea hares species of family Aplysiidae Lamarck, especially Notarchus. leachii cirrosus, Aplysia kurodai and A. pulmonica. It has been used for clinical treatment of cancer and cancer-like diseases in China since the Ming dynasty. Isolation and identification of numerous cytotoxic ingredients from sea hares organisms were reported. Bioactive components of sea hares in China sea including 23 species from six genera of the Aplysiidae were reviewed in this paper. Approximately 300 molecules were identified in 11 species. More than 85 compounds extracted from 7 species were confirmed to have antitumor activity, which indicated that powder of Notarchus would have potential in developing new antineoplastic agents.
School of Bioengineering, Xihua University, Chengdu Sichuan 610039, China.
Xinyu
X
Yang
He
H
Zhu
Wenyu
W
Yang
D000818:Animals; D000970:Antineoplastic Agents / Q000737:chemistry / Q000494:pharmacology*; D035843:Biomedical Research; D049851:Gastropoda / Q000737:chemistry*; D006801:Humans; D008516:Medicine, Chinese Traditional; D015394:Molecular Structure; D009369:Neoplasms / Q000188:drug therapy*; D011208:Powders / Q000737:chemistry / Q000494:pharmacology
D000970:Antineoplastic Agents; D011208:Powders