Photobleaching and blinking of TAMRA induced by Mn(2+).
Blinking and bleaching: Coordination of Mn(2+)  to DNA induces intersystem crossing, causing fluctuations in the fluorescence intensity and accelerated photobleaching.
Department of Chemistry and Biochemistry and The Biodesign Institute, Arizona State University, PO BOX 875601, Tempe, AZ, 85287-5601 USA.
Elana M S
EM
Stennett
Gerdenis
G
Kodis
Marcia
M
Levitus
D004247:DNA / Q000737:chemistry; D005456:Fluorescent Dyes / Q000737:chemistry; D007477:Ions / Q000737:chemistry; D008345:Manganese / Q000737:chemistry*; D038761:Photobleaching; D012235:Rhodamines / Q000737:chemistry*; D013053:Spectrophotometry
C114557:5-carboxytetramethylrhodamine succinimidyl ester; D005456:Fluorescent Dyes; D007477:Ions; D012235:Rhodamines; D008345:Manganese; D004247:DNA