pH- and glucose-responsive core-shell hybrid nanoparticles with controllable metal-enhanced fluorescence effects.
In this paper, a novel core-shell hybrid nanoparticle with a silver core and cross-linked poly(3-acrylamidephenylboronic acid-co-acrylic acid) shell (Ag@PAPBA-PAA) was reported. The prepared hybrid nanoparticles can exhibit good responsiveness to the glucose concentration and pH of the environment and exhibit a responsive swelling and shrinking behavior. Tuned by the glucose concentration or pH, a swelling of up to 15.0 nm thickness of the hybrid nanoparticle shell can be observed. These unique responsive properties can be employed to tune the metal-enhanced fluorescence (MEF) effects of the incorporated Ag cores. The fluorescence of adsorbed positively charged porphyrin molecules (Por(4+)) shows good sensitivity to the glucose concentration and pH with an enhancement of up to about 1.8-fold. These functional hybrid nanoparticles with tunable MEF effects show a great potential application in the fields of responsive fluorescent sensing and detection.
School of Materials Science and Engineering, University of Science and Technology Beijing, Beijing 100083, PR China.
Jianfeng
J
Zhang
Ning
N
Ma
Fu
F
Tang
Qianling
Q
Cui
Fang
F
He
Lidong
L
Li
D001897:Boronic Acids / Q000737:chemistry; D003102:Colloids; D005947:Glucose / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D053758:Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D012834:Silver / Q000737:chemistry*; D013050:Spectrometry, Fluorescence
D001897:Boronic Acids; D003102:Colloids; D012834:Silver; D005947:Glucose; C010686:benzeneboronic acid