Metastasis to the breast from colonic adenocarcinoma.
A 63-year-old woman was referred to a breast surgeon with a breast mass discovered incidentally during follow-up study after colon cancer surgery. Invasive adenocarcinoma was revealed on core needle biopsy. Wide excision of the breast including the tumor was performed. On standard histological examination the tumor showed features of moderately differentiated adenocarcinoma. The immunohistochemistry study revealed positive results for cytokeratin (CK)20 and CDX2, but negative for CK7. These are typical characteristics for colon cancer. Considering her history of subtotal colectomy for sigmoid colon cancer, it is presumable that the mass in the breast was of colonic origin, and it was an extremely rare case of metastasis to the breast from primary colorectal neoplasm. Although the instance is rare, clinicians should keep the possibility of breast metastasis from colorectal cancer in mind for early and correct diagnosis.
Department of Surgery, Ewha Womans University School of Medicine, Seoul, Korea.
Kyoung Tae
KT
Noh
Boyoung
B
Oh
Sun Hee
SH
Sung
Ryung-Ah
RA
Lee
Soon Sup
SS
Chung
Byung In
BI
Moon
Kwang Ho
KH
Kim