First initial community-acquired meningitis due to extended-spectrum beta-lactamase producing Escherichia coli complicated with multiple aortic mycotic aneurysms.
We report the first case of extended-spectrum beta-lactamase producing E. coli community-acquired meningitis complicated with multiple aortic mycotic aneurysms. Because of the acute aneurysm expansion with possible impending rupture on 2 abdominal CT scan, the patient underwent prompt vascular surgery and broad spectrum antibiotic therapy but he died of a hemorrhagic shock. Extended-spectrum beta-lactamase producing E. coli was identified from both blood and cerebrospinal fluid culture before vascular treatment. The present case report does not however change the guidelines of Gram negative bacteria meningitis in adults.
Infectious diseases department, Dron hospital, Tourcoing, France.
Pierre
P
Weyrich
Nicolas
N
Ettahar
Laurence
L
Legout
Agnes
A
Meybeck
Olivier
O
Leroy
Eric
E
Senneville
D000785:Aneurysm, Infected / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D001014:Aortic Aneurysm / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D001769:Blood / Q000382:microbiology; D002555:Cerebrospinal Fluid / Q000382:microbiology; D017714:Community-Acquired Infections / Q000175:diagnosis* / Q000382:microbiology; D004926:Escherichia coli / Q000201:enzymology* / Q000302:isolation & purification; D017809:Fatal Outcome; D006801:Humans; D020814:Meningitis, Escherichia coli / Q000150:complications / Q000175:diagnosis* / Q000382:microbiology; D008875:Middle Aged; D011860:Radiography, Abdominal; D014057:Tomography, X-Ray Computed; D001618:beta-Lactamases / Q000378:metabolism*
D000900:Anti-Bacterial Agents; D001618:beta-Lactamases