A method to assess safety and resilience in radiopharmaceuticals production process.
Radiopharmaceuticals are radiation-emitting substances used in medicine for radiotherapy and imaging diagnosis. A Research Institute, located in Rio de Janeiro, produces three radiopharmaceuticals: the sodium iodate is used in the diagnosis of thyroid dysfunctions, the meta-iodo-benzylguanidine is used in the diagnosis of cardiac diseases, and the fluordesoxyglucose is used in diagnosis in cardiology, oncology, neurology and neuropsychiatry. This paper presents a method to access safety and resilience in radiopharmaceuticals production processes. The method uses resilience indicators in order to proactively evaluate and manage the safety.
Instituto de Engenharia Nuclear, Divisão de Instrumentação e Confiabilidade Humana, Rua Hélio de Almeida 75, Cidade Universitária - Ilha do Fundão, Rio de Janeiro, RJ, Brazil. agrecco@ien.gov.br
Cláudio H S
CH
Grecco
Mario C R
MC
Vidal
Isaac J A L
IJ
Santos
Paulo V R
PV
Carvalho
D001938:Brazil; D006331:Heart Diseases / Q000503:physiopathology*; D006801:Humans; D016272:Occupational Health; D019275:Radiopharmaceuticals / Q000009:adverse effects*; D012308:Risk Management; D012449:Safety; D013961:Thyroid Gland / Q000503:physiopathology*
D019275:Radiopharmaceuticals