Anterior uveitis after treatment of hepatitis C with alpha interferon: the recurrence of a previous inflammatory process due to presumed ocular toxocariasis.
OBJECTIVE
To report a case of recurrent unilateral presumed ocular toxocariasis after treatment of hepatitis C.


METHODS
Case study.


METHODS
Clinical findings, ultrasonography, computed tomography, and serological tests were performed. Once diagnosis was made, effective treatment was administered.


RESULTS
A 46-year-old woman with a long history of decreased unilateral visual acuity presented with anterior uveitis after the use of interferon alpha and ribavirin for treatment of hepatitis C. A biomicroscopic examination revealed active anterior uveitis, with ultrasonography and computed tomography demonstrating a central granuloma due to partially calcified toxocariasis. After treatment with corticosteroids and cycloplegics, the symptoms were alleviated.


CONCLUSIONS
immunostimulation could cause a relapse of the inflammatory reaction found in uveitis due to toxocariasis.
Eduardo F
EF
Damasceno
Nadyr A
NA
Damasceno
D000818:Animals; D000909:Antibodies, Helminth / Q000032:analysis; D000998:Antiviral Agents / Q000009:adverse effects / Q000627:therapeutic use; D003937:Diagnosis, Differential; D004797:Enzyme-Linked Immunosorbent Assay; D015822:Eye Infections, Parasitic / Q000150:complications* / Q000175:diagnosis / Q000469:parasitology; D005260:Female; D005500:Follow-Up Studies; D019698:Hepatitis C, Chronic / Q000188:drug therapy*; D006801:Humans; D016898:Interferon-alpha / Q000009:adverse effects* / Q000627:therapeutic use; D007815:Larva Migrans; D033401:Microscopy, Acoustic; D008875:Middle Aged; D012008:Recurrence; D014057:Tomography, X-Ray Computed; D017166:Toxocara canis / Q000276:immunology / Q000302:isolation & purification*; D014120:Toxocariasis / Q000150:complications* / Q000175:diagnosis / Q000469:parasitology; D014606:Uveitis, Anterior / Q000139:chemically induced* / Q000175:diagnosis
D000909:Antibodies, Helminth; D000998:Antiviral Agents; D016898:Interferon-alpha