Inflammatory myofibroblastic tumor in colon.
Inflammatory myofibroblastic tumor (IMT) is an uncommon mesenchymal solid tumor commonly documented in children and young adults. Here, we report a case of IMT in colon confirmed pathologically after laparoscopic anterior resection. A 35-year-old man presented with anal bleeding after defecation for 2 weeks. Colonoscopy demonstrated a mass with shallow ulceration in the central area and irregular margin accompanied by intact mucosa in the descending colon. Computer tomography showed a well-demarcated and homogenous solitary mass in the descending colon. We performed laparoscopic anterior resection. This case was diagnosed as IMT after microscopic examination. The tumor was composed of a proliferation of spindle-shaped cells arranged in the hyaline material with chronic inflammatory cells, composed mainly of plasma cells and lymphocytes. Immunohistochemically, tumor cells were positive for smooth muscle actin, and vimentin, and negative for desmin, CD117 (c-kit), anaplastic lymphoma kinase-1.
Department of Surgery, The Catholic University of Korea School of Medicine, Seoul, Korea.
Eun Young
EY
Kim
In Kyu
IK
Lee
Yoon Suk
YS
Lee
Naery
N
Yang
Dong Jin
DJ
Chung
Kwang-Il
KI
Yim
Jin Il
JI
Kim
Seung Taek
ST
Oh