YADAMP: yet another database of antimicrobial peptides.
This work presents an antimicrobial peptide database (YADAMP) based on an extensive literature search. This database is focused primarily on bacteria, with detailed information for 2133 peptides active against bacteria. YADAMP was created to facilitate access to critical information on antimicrobial peptides (AMPs). The main difference between YADAMP and other web databases of AMPs is the explicit presence of antimicrobial activity against the most common bacterial strains. YADAMP allows complex queries, easily accessible through a web interface. Peptide information can be retrieved based on peptide name, number of amino acids, net charge, hydrophobic percentage, sequence motif, structure and activity against bacteria. YADAMP is suitable for reviewing information on AMPs and for structure-function analyses of peptides. The database can be accessed via a web-based browser at http://www.yadamp.unisa.it.
Department of Pharmaceutical and Biomedical Sciences, University of Salerno, Via Ponte don Melillo, 84084 Fisciano, Salerno, Italy. piotto@unisa.it
Stefano P
SP
Piotto
Lucia
L
Sessa
Simona
S
Concilio
Pio
P
Iannelli
D000595:Amino Acid Sequence; D000900:Anti-Bacterial Agents / Q000737:chemistry; D023181:Antimicrobial Cationic Peptides / Q000737:chemistry*; D019295:Computational Biology; D016208:Databases, Factual; D057927:Hydrophobic and Hydrophilic Interactions; D020407:Internet; D008826:Microbial Sensitivity Tests; D017433:Protein Structure, Secondary; D020539:Sequence Analysis, Protein; D055672:Static Electricity; D013329:Structure-Activity Relationship; D014584:User-Computer Interface
D000900:Anti-Bacterial Agents; D023181:Antimicrobial Cationic Peptides