Length-dependent dynamics of microtubules.
Certain regulatory proteins influence the polymerization dynamics of microtubules by inducing catastrophe with a rate that depends on the microtubule length. Using a discrete formulation, here we show that, for a catastrophe rate proportional to the microtubule length, the steady-state probability distributions of length decay much faster with length than an exponential decay as seen in the absence of these proteins.
Department of Physics, Indian Institute of Technology, Kanpur 208 016, India.
Vandana
V
Yadav
Sutapa
S
Mukherji
D007700:Kinetics; D008868:Microtubule Proteins / Q000378:metabolism; D008870:Microtubules / Q000378:metabolism*; D008954:Models, Biological; D011336:Probability
D008868:Microtubule Proteins