Sustained response to tocilizumab, anti-IL-6 antibody, following anti-TNF-α failure in a patient with relapsing polychondritis complicated by aortitis.
Department of Rheumatology, West Middlesex University Hospital, Twickenham Road, Isleworth, Middlesex TW7 6AF, London, UK.
Chetan B
CB
Narshi
Simon A
SA
Allard
D000068879:Adalimumab; D000328:Adult; D061067:Antibodies, Monoclonal, Humanized / Q000627:therapeutic use*; D001025:Aortitis / Q000150:complications / Q000188:drug therapy*; D005260:Female; D006801:Humans; D011081:Polychondritis, Relapsing / Q000150:complications / Q000188:drug therapy*; D019947:Receptors, Interleukin-6 / Q000037:antagonists & inhibitors; D016896:Treatment Outcome; D014409:Tumor Necrosis Factor-alpha / Q000037:antagonists & inhibitors
D061067:Antibodies, Monoclonal, Humanized; D019947:Receptors, Interleukin-6; D014409:Tumor Necrosis Factor-alpha; C113250:interleukin-6 receptor alpha; D000068879:Adalimumab; C502936:tocilizumab