Minimization of organocuprate complexity through self-organization: remarkable orientation effect in mixed cuprate π complexes.
They "know" where to go: a powerful orientation effect has been observed in complexes of mixed organocuprates [R(T)R(NT)CuLi] and substrates with C-C, C-N, and C-S double bonds (see scheme; Th=thienyl). The preferred geometry of the intermediate complex sets up the facile addition of R(T) to the double bond, rather than addition of the "dummy ligand", R(NT) .
Department of Chemistry, University of North Carolina-Charlotte, 28223, USA. sbertz1@uncc.edu
Steven H
SH
Bertz
Richard A
RA
Hardin
Michael D
MD
Murphy
Craig A
CA
Ogle
Joshua D
JD
Richter
Andy A
AA
Thomas