HLA Antigens in Omani Psoriasis Vulgaris Patients.
OBJECTIVE
To determine the frequency of different HLA-antigens in patients with plaque psoriasis in the Omani Arab population.


METHODS
Fifty four Omani patients clinically diagnosed with plaque psoriasis attending the dermatology outpatient clinic in Al-Nahdah Hospital (the tertiary dermatology centre in Oman) were selected for HLA studies.


RESULTS
HLA-B52 was present in 20.4% of patients 11/54 and in 5% of controls without psoriasis 5/100. For the association p was <0.004 and the relative risk (RR) was 4.86.


CONCLUSIONS
Psoriasis does not appear to be associated universally with the same HLA antigens. The association of HLA-B52 with plaque psoriasis in Omani patients compares with the HLA-Cw6, -Bw57 and -DR7 preponderance in most other ethnic groups.
Fatma
F
Al-Mamari
Ali
A
Al-Shirawi
Dd
D
Banodkar
Suliman
S
Al-Hashmi
Faiza
F
Al-Yahyaae
Mathew
M
Varghese
Ja
J
Raeburn