Occurrence of erectile dysfunction, testosterone deficiency syndrome and metabolic syndrome in patients with abdominal obesity. Where is a sufficient level of testosterone?
OBJECTIVE
The aim of this study was to determine the prevalence of erectile dysfunction (ED), testosterone deficiency syndrome (TDS), and metabolic syndrome in patients with abdominal obesity (AO) and the prevalence of morbidity at different levels of testosterone (TST).


BACKGROUND
Male sex hormones play an important role in ED and variety of TDS and may have influence on the development of metabolic syndrome. The number of men with AO which constitutes a serious health risk is continuously growing. Currently, there are different views that TST levels are already insufficient, and the patient should benefit from treatment.


OBJECTIVE
This study examined the association between ED, testosterone level and metabolic syndrome in men with AO.


METHODS
The study was carried out in an outpatient urology center of Urology Clinic and Obesity Center of the Clinic of Internal Medicine. There were 167 participants—men with AO which were examined as part of preventive examination.


METHODS
Hormonal, a complete urological and internal evaluation was carried out in every patient.


CONCLUSIONS
We found some degree of ED in 73% (122/167) in men with AO. The TST levels below 14 nmol/l had of these 122 patients 84 patients (68.9%) and 49 patients (40.2%) below 10 nmol/l. In this group of patients, we found 103/167 patients (61.7%) with metabolic syndrome. When we compared TST level and morbidity, we found significantly more patients with diabetes mellitus (DM), hypertension and dyslipidemia in group with TST below 10 nmol/l. We also found difference in the levels of HDL cholesterol and triglycerides in the group of patients with TST 10–14 and over 14 nmol/l.


CONCLUSIONS
Patients over 40 years of age with AO and ED should also be examined for TDS and metabolic syndrome. In this group of patients we found that 113/167 patients (67.6%) had total TST below 14 nmol/l, and sufficient level of TST seems to be above this level.
Department of Urology, Comenius University, Bratislava, Slovakia. juraj.fillo@gmail.com
Juraj
J
Fillo
Jan
J
Breza
Michaela
M
Levčíkova
Jan
J
Luha
Anna
A
Vachulova
Štefan
Š
Durdík
Peter
P
Labaš
D000328:Adult; D000368:Aged; D015992:Body Mass Index; D007172:Erectile Dysfunction / Q000097:blood / Q000453:epidemiology* / Q000209:etiology; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D008297:Male; D024821:Metabolic Syndrome / Q000097:blood / Q000150:complications* / Q000453:epidemiology; D008875:Middle Aged; D056128:Obesity, Abdominal / Q000097:blood / Q000150:complications* / Q000453:epidemiology; D015995:Prevalence; D012189:Retrospective Studies; D018154:Slovakia / Q000453:epidemiology; D013739:Testosterone / Q000097:blood / Q000172:deficiency*
D013739:Testosterone