[Quiscent trophoblastic disease].
METHODS
Case report.


METHODS
Center for trophoblastic disease in Czech Republic, Institute for care of mother and child, 3rd Faculty of Medicine of Charles University Prague.


METHODS
The autors present a case of quiscent trophoblastic disease diagnosed at 27 years old primipara, secundigravida after previous molar pregnancy. The patient had low levels of serum hCG present for more than 18 months after the termination of pregnancy. After this period there was a malignant transformation associated with rapid elevation of hCG levels with need for chemotherapy which was succesfully completed.


CONCLUSIONS
Quiscent (dormant, noninvasive) trophoblastic disease is a recently described unit defined by low levels of hCG present in patients serum and urine samples without any evidence of trophoblastic tumour or other source of hCG production. Quiscent trophoblastic disease is associated with high risk of malignant transformation.
Centrum pro trofoblastickou nemoc v CR, Praha, Ustav pro péci o matku a díte, Praha.
F
F
Hron
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Hejda
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J
Feyereisl
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P
Safár
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H
Sochová
D000328:Adult; D014408:Biomarkers, Tumor / Q000097:blood; D006063:Chorionic Gonadotropin / Q000097:blood; D003937:Diagnosis, Differential; D005260:Female; D031901:Gestational Trophoblastic Disease / Q000175:diagnosis* / Q000503:physiopathology; D006801:Humans; D011247:Pregnancy
D014408:Biomarkers, Tumor; D006063:Chorionic Gonadotropin