Intracranial pressure telemetry: first experience of an experimental in vivo study using a new device.
OBJECTIVE
To test two new telemetric intracranial pressure (ICP) probes (NEUROVENT(®)-P-tel, NEUROVENT(®)-S-tel) in a porcine model. We aimed to intraoperatively correlate the telemetric probes to parenchymal ICP probes and study their reliability in the first hours after implantation. The experimental set-up, new telemetric technology and first data will be presented.


METHODS
We implanted a right parietal (parenchymal) and left parietal (subdural) telemetric ICP probe in 13 Göttingen mini-pigs under general anaesthesia. Through the left parietal burr hole a parenchymal ICP probe (Neurovent(®) ICP) was introduced. Intraoperatively, the head position was changed to provoke ICP changes every 10 min. The telemetric probes were left in situ and finally the parenchymal ICP probe was removed. We correlated mean differences between each telemetric probe and the conventional ICP measurement and Bland-Altman plots were generated for statistical analysis.


RESULTS
We present first data containing intraoperative measurements of 26 telemetric probes after implantation. Intraoperatively, mean differences of 2.48 ± 1.52 mmHg SD (NEUROVENT(®)-P-tel) and 2.64 ± 1.79 mmHg (NEUROVENT(®)-S-tel) were observed. The Bland-Altman plot demonstrates good correlation of the telemetric probes compared with parenchymal ICP probes.


CONCLUSIONS
We present a new telemetric technology that was experimentally compared with a parenchymal ICP probe. We provide data that the new telemetric probes will comparably measure ICP vs an external ICP probe. This stand-alone ICP tool may allow permanent measurement of ICP in hydrocephalus patients. Further continuation of our study will demonstrate whether this system guarantees acceptable long-term reliability.
Department of Neurosurgery, University Hospital Heidelberg, Heidelberg, Germany. berk.orakcioglu@med.uni-heidelberg.de
Berk
B
Orakcioglu
Christopher
C
Beynon
Modar M
MM
Kentar
Regina
R
Eymann
Michael
M
Kiefer
Oliver W
OW
Sakowitz
D000818:Animals; D004567:Electrodes, Implanted; D005260:Female; D007427:Intracranial Pressure / Q000502:physiology*; D023421:Models, Animal; D013355:Subdural Space / Q000502:physiology; D013552:Swine; D013556:Swine, Miniature; D013686:Telemetry / Q000295:instrumentation* / Q000379:methods*