Exciton chirality method in vibrational circular dichroism.
The interaction of two IR chromophores yields a strong vibrational circular dichroism couplet whose sign reflects the absolute configuration of the molecule. We present a method to determine absolute configuration of a chiral molecule based on this couplet without need of theoretical calculation. Not only can this method analyze various molecules whose absolute configuration is difficult to determine by other spectroscopic methods, but also it can significantly enhance VCD signals.
Faculty of Advanced Life Science, Frontier Research Center for Post-Genome Science and Technology, Hokkaido University, Kita 21 Nishi 11, Sapporo 001-0021, Japan. ttaniguchi@sci.hokudai.ac.jp
Tohru
T
Taniguchi
Kenji
K
Monde
D002942:Circular Dichroism; D004952:Esters / Q000737:chemistry*; D007659:Ketones / Q000737:chemistry*; D011789:Quantum Theory; D014732:Vibration
D004952:Esters; D007659:Ketones