Nuclease cleavage-assisted target recycling for signal amplification of free-label impedimetric aptasensors.
A simple, novel, label-free impedimetric aptasensor with signal amplification is developed for ultrasensitive detection of small molecules on a carbon nanotubes-based sensing platform by combining target-induced release of the aptamers and nuclease cleavage-assisted target recycling.
Key Laboratory of Analysis and Detection of Food Safety (Ministry of Education & Fujian Province), Department of Chemistry, Fuzhou University, Fuzhou 350108, PR China.
Juan
J
Tang
Dianping
D
Tang
Jun
J
Zhou
Huanghao
H
Yang
Guonan
G
Chen
D052157:Aptamers, Nucleotide / Q000737:chemistry*; D015374:Biosensing Techniques / Q000379:methods*; D003851:Deoxyribonucleases / Q000737:chemistry*; D004563:Electrochemistry; D037742:Nanotubes, Carbon / Q000737:chemistry*; D013194:Staining and Labeling / Q000379:methods*
D052157:Aptamers, Nucleotide; D037742:Nanotubes, Carbon; D003851:Deoxyribonucleases