Platelet count and mean platelet volume in patients with in-hospital deep venous thrombosis.
OBJECTIVE
To investigate the relationship between mean platelet volume (MPV) and in-hospital deep venous thrombosis (DVT).


METHODS
147 patients with the diagnosis of DVT and 149 control participants were included in the study. For all participants, clinical risk factors, smoking status, and other demographic data were recorded from hospital registries. The data of patients with DVT were compared with the control participants.


RESULTS
Mean MPV was significantly higher in patients with DVT than the control group (8.91 ± 1.86 vs 7.86 ± 0.9; P < .001). Body mass index, smoking frequency, hematocrit, and platelet count were significantly correlated with MPV. Independent predictors of in-hospital DVT were MPV (odds ratio [OR] = 1.5; 95% confidence interval [CI] = 1.2-1.87; P ≤ .001), body mass index (OR = 1.17; 95% CI = 1.04-1.34; P = .012), and smoking (OR = 1.83; 95% CI = 1.09-3.08; P = .023).


CONCLUSIONS
Mean platelet volume was significantly higher in patients with DVT, and it is an independent predictor of in-hospital DVT.
Department of Cardiology, Dicle University, Diyarbakır, Turkey. habibcil@hotmail.com
Habib
H
Cil
Celal
C
Yavuz
Yahya
Y
Islamoglu
Ebru Öntürk
EÖ
Tekbas
Sinan
S
Demirtas
Zuhal Aritürk
ZA
Atilgan
Ercan
E
Gündüz
Emre Demir
ED
Benli
Halis
H
Tanriverdi
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015415:Biomarkers / Q000097:blood; D001792:Blood Platelets; D005260:Female; D006760:Hospitalization; D006801:Humans; D008297:Male; D008875:Middle Aged; D010976:Platelet Count; D012189:Retrospective Studies; D020246:Venous Thrombosis / Q000097:blood*
D015415:Biomarkers