First report of subcutaneous phaeohyphomycosis caused by Ochroconis tshawytschae in an immunocompetent patient.
We report the first case and clinical course of a case of human subcutaneous phaeohyphomycosis caused by Ochroconis tshawytschae, a rare fish pathogen. The diagnosis was based upon histopathological and mycological examinations of clinical samples. Identification of the etiologic agent was assessed on its phenotypic characteristics and subsequently, confirmed by molecular data. In vitro antifungal susceptibility of the isolate was investigated and a comparison was prepared of all of its features to those of its two most relevant related species, O. gallopava and O. humicola.
Department of Mycology, Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing, People's Republic of China.
Yi P
YP
Ge
Gui X
GX
Lv
Yong N
YN
Shen
Min
M
Li
Shu W
SW
Deng
Sybren
S
De Hoog
Kittipan
K
Samerpitak
Wei D
WD
Liu
D000328:Adult; D000935:Antifungal Agents / Q000627:therapeutic use; D001203:Ascomycota / Q000187:drug effects / Q000235:genetics / Q000302:isolation & purification* / Q000472:pathogenicity; D021903:DNA, Ribosomal Spacer / Q000235:genetics; D020459:Genes, rRNA; D006801:Humans; D007121:Immunocompetence; D017964:Itraconazole / Q000627:therapeutic use; D008297:Male; D008826:Microbial Sensitivity Tests; D016533:Mycological Typing Techniques / Q000379:methods; D060446:Phaeohyphomycosis / Q000175:diagnosis / Q000382:microbiology*; D055815:Young Adult
D000935:Antifungal Agents; D021903:DNA, Ribosomal Spacer; D017964:Itraconazole