GDx VCC measurements and blue-on-yellow perimetry in ocular hypertension.
The aim of this work was to investigate the correlation between scanning laser polarimetry with variable corneal compensation (GDx VCC) parameters and blue-on-yellow perimetry (B/YP) indices in ocular hypertension (OHT). One eye each of 52 patients with OHT (with a normal visual field, a normal optic nerve, and an untreated IOP > 21 mmHg) was chosen. All patients were examined with the Octopus 101 automated perimetry dG2 program using the dynamic/normal strategy (white-on-white perimetry, W/WP), with the dG2 program using the dynamic strategy/BY method (blue-on-yellow perimetry, B/YP), and with GDx VCC. Seven of the 52 OHT patients had both B/YP visual field loss and retinal nerve fiber layer (RNFL) defects with the GDx VCC measurements, and four patients demonstrated regions of B/YP visual field defects with corresponding RNFL defects on GDx VCC examination. A mild significant correlation was found between B/YP mean sensitivity (MS) and the superior average (R (2) =0.138, p = 0.049). No significant correlation was found between the W/WP indices and GDx VCC parameters. B/YP MS correlated with the superior average of GDx VCC in OHT patients. The findings brought up the possibility of using both techniques for clinical examination to yield converging data.
Department of Ophthalmology, Ruijin Hospital Affiliated Medical School, Shanghai Jiaotong University, 197 Ruijin No.2 Road, 200025, Shanghai, China. yszhong68@yahoo.com.cn
Yisheng
Y
Zhong
Liping
L
Chen
Yu
Y
Cheng
Fangzhi
F
Yu
D000328:Adult; D003315:Cornea / Q000502:physiology; D005260:Female; D006801:Humans; D007429:Intraocular Pressure; D008297:Male; D008875:Middle Aged; D009798:Ocular Hypertension / Q000175:diagnosis / Q000503:physiopathology*; D009900:Optic Nerve; D012016:Reference Values; D057109:Scanning Laser Polarimetry / Q000379:methods*; D058609:Visual Field Tests / Q000379:methods*