[The clinical study of high-frequency ultrasound-guided vacuum-assisted biopsy for breast microcalcifications].
OBJECTIVE
To evaluate the clinical application of high-frequency ultrasound-guided vacuum-assisted biopsy for breast microcalcifications.


METHODS
Sixty-six patients with 70 lesions of microcalcifications detected at mammography underwent high-frequency ultrasound-guided vacuum-assisted biopsy from July 2009 to October 2010. All patients were female, aged 24 to 61 years (median age 40 years). Among 70 lesions of microcalcifications, unilateral lesions were 62 cases and bilateral lesions were 4 cases. The clinical factors that affected the success of biopsy were investigated by χ(2) test and Logistic regression analysis.


RESULTS
Among 70 lesions of microcalcifications, the successful rate of biopsy was 72.9% (51/70). The biopsy successful rate of microcalcifications without and with masses were 65.2% (30/46) and 87.5% (21/34) respectively (χ(2) = 3.960, P = 0.047). The biopsy successful rate of microcalcifications of maximal diameter more than 5 mm was higher than that of maximal diameter less than 5 mm (88.9% vs. 55.9%, χ(2) = 9.633, P = 0.002). The Logistic regression analysis showed that the types and maximal diameter of microcalcifications were the main factors that affected the success of biopsy.


CONCLUSIONS
The clinical application of high-frequency ultrasound-guided vacuum-assisted biopsy was an effective option for the diagnosis of breast microcalcifications, especially for the type of microcalcifications with masses and the maximal diameter more than 5 mm.
Breast Disease Center, Guangdong Women and Children Hospital of Guangzhou Medical College, Materal and Child Health Hospital of Guangdong, Guangzhou 510010, China.
Zhen-qiang
ZQ
Lian
An-qin
AQ
Zhang
Qi
Q
Wang
Cai-xia
CX
Zhu
Wen-ping
WP
Li
Juan
J
Xu
Hong-yi
HY
Gao
Yun-xiang
YX
Pan
Ling
L
Wu
D000328:Adult; D001707:Biopsy, Needle / Q000379:methods*; D001941:Breast Diseases / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D002114:Calcinosis / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D008875:Middle Aged; D019060:Minimally Invasive Surgical Procedures / Q000379:methods*; D016217:Ultrasonography, Mammary / Q000379:methods*