Antioxidative properties of functional polyphenols and their metabolites assessed by an ORAC assay.
We compared the antioxidative activities of polyphenol metabolites with those of intact functional polyphenols by an assay of the oxygen radical absorbance capacity (ORAC). The metabolites of ellagitannin geraniin, chlorogenic acid, and (-)-epigallocatechin gallate displayed more potent antioxidative activity than their respective original compounds. Our findings suggest that these metabolites may play important roles as biological antioxidants after their consumption.
Division of Pharmaceutical Sciences, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
Hidekazu
H
Ishimoto
Akihiro
A
Tai
Morio
M
Yoshimura
Yoshiaki
Y
Amakura
Takashi
T
Yoshida
Tsutomu
T
Hatano
Hideyuki
H
Ito
D000975:Antioxidants / Q000032:analysis / Q000378:metabolism*; D002392:Catechin / Q000031:analogs & derivatives / Q000378:metabolism; D002726:Chlorogenic Acid / Q000378:metabolism; D047348:Hydrolyzable Tannins / Q000378:metabolism; D059808:Polyphenols / Q000378:metabolism*; D017382:Reactive Oxygen Species
D000975:Antioxidants; D047348:Hydrolyzable Tannins; D059808:Polyphenols; D017382:Reactive Oxygen Species; D002726:Chlorogenic Acid; D002392:Catechin; C045651:epigallocatechin gallate