[Systemic lupus erythematosus].
Systemic lupus erythematosus (SLE) is a chronic syndrome with unknown etiology and polymorphic clinical picture occurring mainly in women. The patients have immunological abnormalities such as autoantibodies against nuclear structures. The prognosis has improved due to active early diagnostics and more efficient treatment of the disease. Mild forms of the disease are associated with fatigue, articular and muscular symptoms, skin rashes, pleuritis or pericarditis and minor changes in the blood. Severe SLE involves glomerulonephritis, complications in the central nervous system, cardiac and pulmonary complications and major changes in the blood.
HYKS, medisiininen tulosyksikkö, Peijaksen sairaala.
Heikki
H
Julkunen
D002908:Chronic Disease; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000175:diagnosis / Q000276:immunology / Q000628:therapy; D008297:Male; D011379:Prognosis