Biomineralization of superhydrophilic vertically aligned carbon nanotubes.
Vertically aligned carbon nanotubes (VACNT) promise a great role for the study of tissue regeneration. In this paper, we introduce a new biomimetic mineralization routine employing superhydrophilic VACNT films as highly stable template materials. The biomineralization was obtained after VACNT soaking in simulated body fluid solution. Detailed structural analysis reveals that the polycrystalline biological apatites formed due to the -COOH terminations attached to VACNT tips after oxygen plasma etching. Our approach not only provides a novel route for nanostructured materials, but also suggests that COOH termination sites can play a significant role in biomimetic mineralization. These new nanocomposites are very promising as nanobiomaterials due to the excellent human osteoblast adhesion.
Laboratory of Biomedical Nanotechnology, University of Vale do Paraiba (Univap), São José dos Campos, SP, Brazil.
Teresa Cristina O
TC
Marsi
Tiago G
TG
Santos
Cristina
C
Pacheco-Soares
Evaldo J
EJ
Corat
Fernanda R
FR
Marciano
Anderson O
AO
Lobo
D001672:Biocompatible Materials / Q000737:chemistry; D002448:Cell Adhesion / Q000502:physiology; D006801:Humans; D008567:Membranes, Artificial; D053761:Nanocomposites / Q000737:chemistry* / Q000648:ultrastructure; D037742:Nanotubes, Carbon / Q000737:chemistry* / Q000648:ultrastructure; D010006:Osteoblasts / Q000166:cytology
D001672:Biocompatible Materials; D008567:Membranes, Artificial; D037742:Nanotubes, Carbon