Nephrotic syndrome: a rare cause of acute coronary syndrome in a child.
Patients with nephrotic syndrome are at risk of developing thrombosis in both veins and arteries. Various manifestations in different organs have been reported. Thrombi in heart seen, associated with multiorgan thrombosis have been reported on autopsy earlier, but only once in a living patient with nephrotic syndrome. Here, we report a 13 years old boy with steroid-resistant nephrotic syndrome, who developed an asymptomatic but potentially hazardous large intracardiac thrombus. The child developed nephrotic syndrome at the age of 9 years and had multiple recurrences. At the age of 13 years, he developed myocardial infarction (MI) due to embolism from a large intracardiac thrombus. Later on, he was treated with heparin and warfarin anticoagulation.
Unit II, National Institute of Cardiovascular Diseases, Karachi, Pakistan. javaidarifkhankhan@yahoo.com.au
Javaid Arif
JA
Khan
Tariq
T
Masood
Fahad
F
Shamsi
D054058:Acute Coronary Syndrome / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D056988:Anterior Wall Myocardial Infarction / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology*; D000925:Anticoagulants / Q000627:therapeutic use; D017023:Coronary Angiography; D003328:Coronary Thrombosis / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000503:physiopathology; D018450:Disease Progression; D015150:Echocardiography, Doppler; D004562:Electrocardiography / Q000379:methods; D005500:Follow-Up Studies; D006493:Heparin / Q000627:therapeutic use; D006801:Humans; D008297:Male; D009404:Nephrotic Syndrome / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D035583:Rare Diseases; D012008:Recurrence; D018570:Risk Assessment; D012720:Severity of Illness Index; D016896:Treatment Outcome; D014859:Warfarin / Q000627:therapeutic use
D000305:Adrenal Cortex Hormones; D000925:Anticoagulants; D014859:Warfarin; D006493:Heparin