Iron-catalysed tandem cross-dehydrogenative coupling (CDC) of terminal allylic C(sp3) to C(sp2) of styrene and benzoannulation in the synthesis of polysubstituted naphthalenes.
A novel iron-catalysed tandem cross-dehydrogenative coupling and benzoannulation process was developed for the synthesis of biologically and synthetically important polysubstituted naphthalene derivatives from simple 1,2-aryl-propenes and styrenes in moderate to good yields.
School of Pharmacy and Shanghai Key Laboratory of Functional Materials Chemistry, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, China.
Hua
H
Liu
Li
L
Cao
Jia
J
Sun
John S
JS
Fossey
Wei-Ping
WP
Deng
D000475:Alkenes / Q000737:chemistry; D002384:Catalysis; D003500:Cyclization; D007501:Iron / Q000737:chemistry*; D008956:Models, Chemical; D009281:Naphthalenes / Q000138:chemical synthesis* / Q000737:chemistry; D020058:Styrene / Q000737:chemistry*
D000475:Alkenes; D009281:Naphthalenes; D020058:Styrene; C013658:propylene; D007501:Iron