Fiber-probe detection for positron-emission-assisted Cherenkov-radiation brain mapping.
Suitably designed optical fibers are shown to offer a powerful tool for functional brain mapping, facilitating the detection of Cherenkov radiation generated by relativistic positrons from positron-emitting radionuclides. Fiber probes support a low-loss delivery of the high-intensity short-wavelength part of the Cherenkov spectrum, which is strongly absorbed by biotissues, and lower the threshold positron energy ε required for Cherenkov radiation relative to ε values typical of biotissues, thus enhancing the conversion of positron energy into Cherenkov radiation.
Department of Neuroscience, NBIC Center, Kurchatov Institute National Research Center, Moscow, Russia. zheltikov@phys.msu.ru
Aleksei
A
Zheltikov
Konstantin
K
Anokhin
D000818:Animals; D001921:Brain / Q000166:cytology / Q000502:physiology* / Q000528:radiation effects*; D004583:Electrons; D059907:Functional Neuroimaging / Q000295:instrumentation*; D055100:Optical Fibers