Prostatic abscess in a pediatric patient with chronic granulomatous disease: report of a unique case and review of the literature.
Chronic granulomatous disease (CGD) is a rare hereditary disease in which phagocytes have difficulty forming the superoxide radical required to kill certain pathogens. Individuals with CGD are susceptible to a specific set of infections and granulomatous lesions. We present the case of a 15-year-old boy with X-linked CGD who presented with unremitting cough and fevers. He had a left-sided pneumonia that persisted despite home intravenous antibiotics. He was admitted to an outside facility for bronchoalveolar lavage to obtain cultures and polymerase chain reaction. Computed tomography of chest, abdomen, and pelvis was done for baseline evaluation of extent of disease. Computed tomography revealed a fluid collection in the prostatic fossa, later determined to be a prostatic abscess. To our knowledge, this is the first reported case of a prostatic abscess in a pediatric patient with CGD.
Urologic Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892-1210, USA.
Nnenaya Q
NQ
Agochukwu
Ardeshir R
AR
Rastinehad
Lee A
LA
Richter
Stephanie
S
Barak
Christa S
CS
Zerbe
Steven M
SM
Holland
Peter A
PA
Pinto
D000038:Abscess / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology* / Q000601:surgery; D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D019121:Burkholderia Infections / Q000150:complications / Q000188:drug therapy; D016956:Burkholderia cepacia / Q000302:isolation & purification; D002176:Candida albicans / Q000302:isolation & purification; D024901:Drug Resistance, Multiple, Bacterial; D005334:Fever / Q000209:etiology; D006105:Granulomatous Disease, Chronic / Q000150:complications*; D006801:Humans; D016867:Immunocompromised Host; D033162:Incidental Findings; D008297:Male; D018410:Pneumonia, Bacterial / Q000150:complications / Q000000981:diagnostic imaging; D011472:Prostatitis / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology* / Q000601:surgery; D014057:Tomography, X-Ray Computed; D020728:Transurethral Resection of Prostate
D000900:Anti-Bacterial Agents