Profound hypoglycemia presents with reversible symmetrical ADC signal changes isolated to eloquent cortex of the parietal lobe.
MRI diffusion/ADC signal change with reversal, symmetrically isolated to the cortex of the precentral gyri in profound hypoglycemia has not been previously described. We present a case in which minimal cortical signal change without deep gray matter involvement and subsequent reversal occurred without significant clinical improvement. Correlation of the reversal of diffusion/ADC signal to findings by EEG evaluation has been described in animal studies and not in humans before.
OSF St. Joseph Medical Center, 2200 East Washington Street, Bloomington, IL 61701, USA.
Marietta
M
Walsh
Ajeet
A
Gordhan
Amit
A
Vyas
Herman J
HJ
Dick
D000368:Aged; D002540:Cerebral Cortex / Q000473:pathology*; D003937:Diagnosis, Differential; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods; D005260:Female; D006801:Humans; D007003:Hypoglycemia / Q000175:diagnosis* / Q000503:physiopathology; D010296:Parietal Lobe / Q000473:pathology*