Ovarian incidentaloma.
Incidental adnexal masses occur with relatively high frequency in post-menopausal women, with a prevalence rate of 3.3-18% in asymptomatic patients. Unilocular, benign-appearing ovarian cysts represent the vast majority of abnormal findings at transvaginal ultrasonography. As many as 80% will resolve over a period of several months; if persistent, unchanged, less than 10 cm, and with normal CA-125 values, the likelihood of an invasive cancer is sufficiently low that observation should be offered. More recent investigations support the use of secondary imaging modalities such as MRI, which may help differentiate benign from malignant masses. Surgical management plays a key role when patients are symptomatic regardless of age, menopausal and have documented changes in cyst characteristics, experience elevations in tumor markers or have symptoms suggestive of a hormone-producing neoplasm. High level, evidence-based screening guidelines have yet to be developed.
Department of Obstetrics and Gynecology, Cedars-Sinai Medical Center, Geffen School of Medicine at UCLA, Los Angeles, CA 90048, USA. solnikm@cshs.org
Meir Jonathon
MJ
Solnik
Carolyn
C
Alexander
D000291:Adnexal Diseases / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000601:surgery; D000328:Adult; D014408:Biomarkers, Tumor / Q000032:analysis; D018394:CA-125 Antigen / Q000097:blood; D004715:Endometriosis / Q000175:diagnosis; D004958:Estradiol / Q000097:blood; D005260:Female; D006801:Humans; D033162:Incidental Findings; D008279:Magnetic Resonance Imaging; D008403:Mass Screening; D008597:Menstrual Cycle; D008875:Middle Aged; D010048:Ovarian Cysts / Q000175:diagnosis* / Q000000981:diagnostic imaging; D010051:Ovarian Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging; D017698:Postmenopause; D011237:Predictive Value of Tests; D014463:Ultrasonography
D014408:Biomarkers, Tumor; D018394:CA-125 Antigen; D004958:Estradiol