A rare case of juvenile acute non-proliferative glomerulonephritis with a 6-year follow-up experience.
Juvenile acute non-proliferative glomerulonephritis (JANG) is a relatively new clinico-pathological entity established in 2000. A PubMed search revealed only two published reports encompassing 14 cases of JANG. It is distinguished from acute post-streptococcal glomerulonephritis by the presence of normal serum complement and the absence of diffuse proliferation of mesangial cells in the glomeruli. We report a case of a 4-year-old child that presented with a clinical scenario and renal biopsy findings consistent with JANG. She responded well to treatment with high-dose methylprednisolone for 3 days, followed by gradual taper with oral prednisone. She was monitored closely for a period of 6 years and continues to do well with normal renal parameters and without any medications.
Division of Nephrology, Department of Medicine, University of Toledo, OH 3000 Arlington Avenue, Toledo, OH 43614, USA. vamsepriya@yahoo.co.in
Vamsee Priya
VP
Marina
Ridwan
R
Tarabishi
Deepak
D
Malhotra
D000208:Acute Disease; D000284:Administration, Oral; D001706:Biopsy; D002675:Child, Preschool; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D005921:Glomerulonephritis / Q000175:diagnosis* / Q000188:drug therapy; D005938:Glucocorticoids / Q000008:administration & dosage; D006801:Humans; D007678:Kidney Glomerulus / Q000473:pathology*; D008775:Methylprednisolone / Q000008:administration & dosage*
D005938:Glucocorticoids; D008775:Methylprednisolone