Entrapment of protein in nanotubes formed by a nanochannel and ion-channel hybrid structure of anodic alumina.
The nanochannel (in a porous layer) and ion-channel (in a barrier layer) hybrid structure of anodic alumina is used as a protein-trapping device. The transmembrane potential drives the electromigration of the charged proteins (FITC-labeled) into the nanochannels, but electromigration across the barrier layer is impossible due to the size-exclusion effect. As a result, the proteins can be continuously trapped in the nanochannels.
State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, China.
Wei
W
Chen
Bo
B
Jin
Yu-Lin
YL
Hu
Yu
Y
Lu
Xing-Hua
XH
Xia
D000537:Aluminum Oxide / Q000737:chemistry*; D007473:Ion Channels / Q000737:chemistry*; D036103:Nanotechnology / Q000379:methods*; D043942:Nanotubes / Q000737:chemistry*; D011506:Proteins / Q000737:chemistry*
D007473:Ion Channels; D011506:Proteins; D000537:Aluminum Oxide