Use of osteoplastic material to guide bone tissue regeneration deffect.
The goal of research was study of restoration processes in jaw-teeth bone defects by application of osteoplastic materials in the experiment.  The experiment was performed over 32 white (6-12 month old) rats; the animals were divided into 2 groups; 16 animals were enrolled in the first group; the section was performed in the edge of lower jaw; the lower jaw body was revealed. Under the effect of the dental drilling machine and the # 1 cooling mean by the fissure bohrium (distilled water) the defect of the dimension of 2x2 mm was created; the defect was washed by 0/9% saline to remove the bone sawdust; the wound was sutured tightly, in layers.  The second group of the experiment was staffed with 16 animals (main group); the similar bone defect of the size 2 x 2mm was created on the rat's jaw's body.  After washing of modeled defect we inserted osteopathic materials PORESORB-TCP crystals with the size of 0,6-1.0 mm the wound was sutured tightly, in layers. After the 3-rd, 15-th, 30-th and 90-th days from the date of operation there was performed X-ray and morphological examination over the animals in the control as well as the main group.  The analysis of the examination performed over the experimental materials showed that in the control group in samples taken at 90th day  the defects were not completely restored. In the test group in samples taken at 90th day  reparative regeneration is confirmed. This is stimulated by the factor that within the main group's animals the defect regeneration process is supported with the osteoplastic material PORESORB-TCP.
Ilia State University, Scientific Research Institute of Medicine, Tbilisi, Georgia.
A
A
Machavariani
K
K
Mazmishvili
T
T
Grdzelidze
G
G
Menabde
I
I
Amiranashvili
D016301:Alveolar Bone Loss / Q000188:drug therapy* / Q000601:surgery; D000818:Animals; D001672:Biocompatible Materials / Q000627:therapeutic use*; D001861:Bone Regeneration; D018786:Bone Substitutes / Q000627:therapeutic use*; D008297:Male; D008334:Mandible / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D011859:Radiography; D051381:Rats
D001672:Biocompatible Materials; D018786:Bone Substitutes