A new magnetic resonance imaging scoring system for perilymphatic space appearance after intratympanic gadolinium injection, and its clinical application.
OBJECTIVE
To establish a new magnetic resonance imaging scoring system for diagnosing endolymphatic hydrops.


METHODS
A total of 214 ears of 107 patients were categorised into five groups: no symptoms, Ménière's disease, sudden deafness, delayed endolymphatic hydrops and other ear disorders. Gadolinium distribution within the labyrinth was scored separately and quantitatively by two radiologists. Multiple independent-sample non-parametric tests, Bayesian discriminant analysis, multivariate logistic regression and receiver operating characteristic curve analyses were performed.


RESULTS
The derived scoring model was highly accurate for diagnosing Ménière's disease and delayed endolymphatic hydrops. Two magnetic resonance imaging scoring methods for the perilymphatic space were proposed for the diagnosis of endolymphatic hydrops: a pre-1 value (a new variable that predicts individual probability) of more than 0.3982299, or a sum of all labyrinth component scores of less than 14.5.


CONCLUSIONS
A convenient method is proposed which offers reliable radiological diagnostic criteria for Ménière's disease and delayed endolymphatic hydrops.
Department of Imaging, First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian Province, People's Republic of China.
Z-M
ZM
Fang
X
X
Chen
X
X
Gu
Y
Y
Liu
R
R
Zhang
D-R
DR
Cao
H-G
HG
He
D000328:Adult; D003287:Contrast Media / Q000008:administration & dosage / Q000493:pharmacokinetics*; D016002:Discriminant Analysis; D007758:Ear, Inner / Q000378:metabolism*; D018159:Endolymphatic Hydrops / Q000175:diagnosis*; D019786:Gadolinium DTPA / Q000008:administration & dosage / Q000493:pharmacokinetics*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D016015:Logistic Models; D008279:Magnetic Resonance Imaging / Q000379:methods* / Q000592:standards; D008297:Male; D008575:Meniere Disease / Q000175:diagnosis*; D012680:Sensitivity and Specificity
D003287:Contrast Media; D019786:Gadolinium DTPA