Dual polarisation interferometry for real-time, label-free detection of interaction of mercury(II) with mercury-specific oligonucleotides.
A real-time, label-free dual polarisation interferometry technique was used to investigate the interaction of Hg(2+) with a 21-mer T-rich oligonucleotide and further construct a Hg(2+) biosensor based on thymine-Hg(2+)-thymine coordination chemistry.
State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin 130022, China.
Yong
Y
Wang
Yu
Y
Zheng
Fan
F
Yang
Xiurong
X
Yang
D015374:Biosensing Techniques; D002942:Circular Dichroism; D007368:Interferometry; D008628:Mercury / Q000737:chemistry*; D009841:Oligonucleotides / Q000737:chemistry*; D011094:Polyethyleneimine / Q000737:chemistry; D013941:Thymine / Q000737:chemistry
D009841:Oligonucleotides; D011094:Polyethyleneimine; D008628:Mercury; D013941:Thymine