Scale-free duplication dynamics: a model for ultraduplication.
Empirical studies of the genome-wide length distribution of duplicated sequences have revealed an algebraic tail common to nearly all clades. The decay of the tail is often well approximated by a single exponent that takes values within a limited range. We propose and study here scale-free duplication dynamics, a class of model for genome sequence evolution that generates the observed shapes of this distribution. A transition between self-similar and non-self-similar regimes is exhibited. Our model accounts plausibly for the observed form of the algebraic tail, which is not produced by standard models for generating long-range sequence correlations.
Physics and Biology Unit, Okinawa Institute of Science and Technology Suzaki 12-22, Uruma, Okinawa 904-2234, Japan.
M V
MV
Koroteev
J
J
Miller
D001483:Base Sequence; D020440:Gene Duplication / Q000235:genetics*; D023281:Genomics; D008957:Models, Genetic