[Factors determining prognosis of patients with stable  ischemic heart disease (results of a five years prospective study)].
Risk stratification seems to be very important in patients with stable coronary artery disease (CAD). However, the prognostic scales are now available only for the early risk assessment in patients with acute coronary syndromes and in patients undergoing percutaneous coronary interventions. Aim of the study was to assess the frequency of cardiovascular events (CVE) during 5 years of follow-up in patients with stable CAD and to construct a long-term risk prediction model for these patients. 503 patients (mean age 59.4 years) were included in the study. The follow-up period ranged between 3.0 and 7.5 years (mean 5.0 years). Main end points were fatal and non-fatal cardiovascular events: cardiovascular death, acute coronary syndromes, ischemic stroke, transient ischemic attack, peripheral arterial thrombosis, and need for revascularization in any affected vascular area. Total frequency of events was 31.0% (5.7/100 patient years). Independent predictors of events were: severity of angina, three vessel coronary disease, previous myocardial infarction, previous stroke/ transient ischemic attack, peripheral arterial disease, obesity, chronic kidney disease and history of erosive gastritis. The presence of more or equal 3 risk factors was significantly associated with increased frequency of CVE.
A L
AL
Komarov
O O
OO
Shakhmatova
T A
TA
Il'ishchenko
G V
GV
Dzhalilova
A D
AD
Deev
E P
EP
Panchenko
D015984:Causality; D002423:Cause of Death; D003331:Coronary Vessels / Q000473:pathology*; D003661:Decision Support Techniques; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015233:Models, Statistical; D008991:Monitoring, Physiologic; D017202:Myocardial Ischemia / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology / Q000503:physiopathology / Q000628:therapy; D009204:Myocardial Revascularization / Q000379:methods*; D011446:Prospective Studies; D018570:Risk Assessment; D012720:Severity of Illness Index; D013927:Thrombosis / Q000453:epidemiology / Q000209:etiology / Q000503:physiopathology; D013995:Time