Toxic anterior segment syndrome outbreak after vitrectomy and silicone oil injection.
OBJECTIVE
To report a rare outbreak of toxic anterior segment syndrome (TASS) in 4 patients who underwent vitrectomy with silicone oil injection.


METHODS
Review of the medical charts of all patients who underwent surgery in the operating theater of our department during a 10-day period in May 2011.


RESULTS
We report on 4 patients who developed TASS after vitrectomy with silicone oil injection. The clinical presentation was typical of TASS, and different from the anterior chamber reaction that may occur after silicone oil injection. All cases were treated effectively with topical steroids, and the outbreak stopped after the silicone oil batch was exchanged.


CONCLUSIONS
We discuss the possible mechanisms for this unusual TASS outbreak, and suggest the silicone oil as its cause.
Department of Ophthalmology, Tel Aviv Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel. elad_moi@netvision.net.il
Elad
E
Moisseiev
Adiel
A
Barak
D000368:Aged; D000869:Anterior Eye Segment; D004196:Disease Outbreaks; D058450:Endotamponade; D005128:Eye Diseases / Q000188:drug therapy / Q000453:epidemiology* / Q000378:metabolism; D005337:Fibrin / Q000378:metabolism; D005466:Fluorocarbons / Q000008:administration & dosage; D005938:Glucocorticoids / Q000008:administration & dosage; D006801:Humans; D008297:Male; D008875:Middle Aged; D012163:Retinal Detachment / Q000601:surgery; D012772:Shock, Septic / Q000188:drug therapy / Q000453:epidemiology* / Q000378:metabolism; D012827:Silicone Oils / Q000009:adverse effects*; D013046:Specific Gravity; D014821:Vitrectomy / Q000009:adverse effects*; D018630:Vitreoretinopathy, Proliferative / Q000601:surgery
D005466:Fluorocarbons; D005938:Glucocorticoids; D012827:Silicone Oils; D005337:Fibrin; C042852:perflutren