Structure elucidation and NMR assignments of new spirosolane alkaloids from Solanum campaniforme.
From the leaves of Solanum campaniforme, two new spirosolane alkaloids β-acetoxyl-(25S)-22βN-spirosol-4-en-3-one (1) and β-hydroxyl-(25S)-22βN-spirosol-4-en-3-one (4) were isolated along with two other known alkaloids of the same class (25S)-22βN-spirosol-1,4-dien-3-one (2) and (25S)-22βN-spirosol-4-en-3-one (3), which are reported for the first time as natural products. The structures of all alkaloids were established after an extensive analysis by 1D and 2D NMR spectroscopy (COSY, HSQC, HMBC and NOESY) as well as HRESIMS.
Departamento de Química Orgânica e Inorgânica, Universidade Federal do Ceará, 12.200, Fortaleza-CE, 60.021-970, Brazil.
Maria Conceição M
MC
Torres
José Gustavo L
JG
Almeida
Raimundo
R
Braz-Filho
Edilberto R
ER
Silveira
Otília Deusdênia L
OD
Pessoa
D000470:Alkaloids / Q000737:chemistry* / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010840:Phytosterols / Q000737:chemistry / Q000302:isolation & purification; D018515:Plant Leaves / Q000737:chemistry; D012015:Reference Standards; D012991:Solanaceous Alkaloids / Q000737:chemistry / Q000302:isolation & purification; D032322:Solanum / Q000737:chemistry*
D000470:Alkaloids; D010840:Phytosterols; D012991:Solanaceous Alkaloids