Contemporary management of overactive bladder.
Overactive bladder is a prevalent condition with bothersome symptoms that greatly impact health-related quality of life. Despite a multitude of treatment options, many patients go untreated or undertreated. This article addresses the contemporary management of overactive bladder, including behavioral and lifestyle modifications, pelvic floor muscle therapy, biofeedback, drug therapy, neuromodulation, and botulinum toxin. We highlight the new drugs and therapies that have been brought into clinical use over the past few years, and discuss important clinical implications of therapy as well as promising new agents that are currently in advanced stages of development.
Division of Urology, University of Pennsylvania, Philadelphia, PA 19106, USA. ariana.smith@uphs.upenn.edu
Ariana L
AL
Smith
Alan J
AJ
Wein
D018726:Anti-Dyskinesia Agents / Q000627:therapeutic use; D001676:Biofeedback, Psychology; D001905:Botulinum Toxins / Q000627:therapeutic use; D003248:Constipation / Q000150:complications / Q000628:therapy; D004032:Diet; D004599:Electric Stimulation Therapy; D005081:Exercise Therapy; D006801:Humans; D018727:Muscarinic Antagonists / Q000627:therapeutic use; D010276:Parasympatholytics / Q000627:therapeutic use; D017773:Pelvic Floor / Q000502:physiology; D016540:Smoking Cessation; D053201:Urinary Bladder, Overactive / Q000209:etiology / Q000628:therapy*; D015431:Weight Loss
D018726:Anti-Dyskinesia Agents; D018727:Muscarinic Antagonists; D010276:Parasympatholytics; D001905:Botulinum Toxins