Microscale and nanoscale compartments for biotechnology.
Compartmentalization is essential in the organization of biological systems, playing a fundamental role in modulating biochemical activity. An appreciation of the impact that biological compartments have on chemical reactions and an understanding of the physical and chemical phenomena that affect their assembly and function have inspired the development of synthetic compartments. Organic compartments assembled from amphiphilic molecules or derived from biological materials, have formed the basis of initial work in the field. However, inorganic and hybrid organic-inorganic compartments that capitalize on the optical and catalytic properties of metal and semiconductor materials are emerging. Methods for arraying these microcompartment and nanocompartment materials in higher order systems promise to enable the scaling and integration of these technologies for industrial and commercial applications.
Biosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN, United States.
Scott T
ST
Retterer
Michael L
ML
Simpson
D001709:Biotechnology / Q000295:instrumentation / Q000379:methods*; D004798:Enzymes / Q000737:chemistry; D007700:Kinetics; D008670:Metals / Q000737:chemistry; D049329:Nanostructures / Q000737:chemistry*; D036103:Nanotechnology / Q000295:instrumentation / Q000379:methods*; D012666:Semiconductors
D004798:Enzymes; D008670:Metals