Optoelectronic capillary sensors in microfluidic and point-of-care instrumentation.
This paper presents a review, based on the published literature and on the authors' own research, of the current state of the art of fiber-optic capillary sensors and related instrumentation as well as their applications, with special emphasis on point-of-care chemical and biochemical sensors, systematizing the various types of sensors from the point of view of the principles of their construction and operation. Unlike classical fiber-optic sensors which rely on changes in light propagation inside the fiber as affected by outside conditions, optical capillary sensors rely on changes of light transmission in capillaries filled with the analyzed liquid, which opens the possibility of interesting new applications, while raising specific issues relating to the construction, materials and instrumentation of those sensors.
Institute of Microelectronics and Optoelectronics, Warsaw University of Technology, Koszykowa 75, 00-662 Warsaw, Poland. borecki@imio.pw.edu.pl
Michał
M
Borecki
Michael L
ML
Korwin-Pawlowski
Maria
M
Beblowska
Jan
J
Szmidt
Andrzej
A
Jakubowski
D015374:Biosensing Techniques / Q000295:instrumentation / Q000379:methods*; D002196:Capillaries / Q000378:metabolism; D005336:Fiber Optic Technology / Q000295:instrumentation* / Q000379:methods; D006801:Humans; D008027:Light; D044085:Microfluidics / Q000295:instrumentation*; D055100:Optical Fibers; D019095:Point-of-Care Systems