A novel entry to functionalized benzofurans and indoles via palladium(0)-catalyzed arylative dearomatization of furans.
A novel entry to functionalized benzofurans and indoles from furans in moderate to good yields has been developed. This protocol involves palladium(0)-catalyzed dearomatizing intramolecular arylation of the furan ring, formation of a π-allylic palladium complex, furan ring opening, and a β-hydride elimination sequence.
School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou, Guangdong, 510640, China. blyin@scut.edu.cn
Biaolin
B
Yin
Congbi
C
Cai
Guohui
G
Zeng
Ruoqi
R
Zhang
Xiang
X
Li
Huanfeng
H
Jiang
D001572:Benzofurans / Q000138:chemical synthesis*; D002384:Catalysis; D005663:Furans / Q000737:chemistry*; D007211:Indoles / Q000737:chemistry*; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*
D001572:Benzofurans; D005663:Furans; D007211:Indoles; D010165:Palladium