First results of clampless distal anastomosis in peripheral vascular bypass with LeGoo, a thermoreversible polymer.
BACKGROUND
We report our initial experience with LeGoo (Pluromed Inc, Woburn, Mass), a temporary thermoreversible occlusive gel, in peripheral vascular revascularization.


METHODS
Between 2007 and 2010, LeGoo was used to occlude target vessels during bypass surgery in 14 patients who required infrainguinal revascularization.


RESULTS
Proximal occlusion of the target vessel was obtained with a mean quantity of 0.25 mL of LeGoo. Distal occlusion of the vessel was obtained with a mean quantity of 0.28 mL. One injection of LeGoo was sufficient to prevent backbleeding in 11 of 14 patients. The mean occlusion time was 13.4 ± 3.3 minutes. An injection of saline through the graft or better directly into the arteries was used to dissolve the gel. For our first case, a Fogarty catheter was used to remove residual gel from the anterior tibial artery.


CONCLUSIONS
LeGoo gel can be used to stop blood flow in small-bore arteries in the lower limbs to allow anastomoses to be performed.
Service de chirurgie cardio vasculaire CHU Le Bocage, Dijon, France. benjamin.kretz@wanadoo.fr
Benjamin
B
Kretz
Eric
E
Steinmetz
Roger
R
Brenot
Olivier
O
Bouchot
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000714:Anastomosis, Surgical; D016063:Blood Loss, Surgical / Q000517:prevention & control*; D001831:Body Temperature; D003250:Constriction; D005240:Feasibility Studies; D005260:Female; D005602:France; D006489:Hemostatic Techniques; D006801:Humans; D035002:Lower Extremity / Q000098:blood supply; D008297:Male; D008875:Middle Aged; D016491:Peripheral Vascular Diseases / Q000401:mortality / Q000601:surgery*; D044367:Phase Transition; D020442:Poloxamer / Q000009:adverse effects / Q000737:chemistry / Q000627:therapeutic use*; D016896:Treatment Outcome; D014656:Vascular Surgical Procedures / Q000009:adverse effects / Q000401:mortality
C539704:LeGoo; D020442:Poloxamer