[The application of cobaltferous markers in serodiagnostic assay of infectious diseases].
The study was targeted to the investigation of possibilities of using in immunological analysis the sols on basis of bivalent cobalt compounds as a catalytic marker to ensure the trusted visual registration of analysis results in immunology reactions plats. The results of comparative evaluation of immune-enzyme and immune catalytic tests on the basis of several commercial diagnostic test systems of various national manufacturers are presented. The conclusion is derived that by the sensitivity and specificity the cobaltferous immunosols are not inferior to immuneperoxidase conjugated metabolites and even have an advantage due to the relative simplicity of immunosol preparation and the possibility of trusted non-instrument registration of results. The application of cobaltferous immunosols permits to develop the diagnostic test systems with trusted visual registration of results following the "yes-no" principle to ensure the immunodiagnostics in poorly equipped laboratories.
A G
AG
Poltavchenko
P V
PV
Filatov
D000880:Anthraquinones / Q000737:chemistry; D002384:Catalysis; D003035:Cobalt / Q000737:chemistry*; D003141:Communicable Diseases / Q000175:diagnosis* / Q000276:immunology; D005295:Ferrocyanides / Q000737:chemistry; D016480:Helicobacter pylori / Q000276:immunology / Q000302:isolation & purification; D006801:Humans; D007124:Immunoenzyme Techniques; D007074:Immunoglobulin G / Q000276:immunology; D012698:Serologic Tests / Q000379:methods*; D014122:Toxoplasma / Q000276:immunology / Q000302:isolation & purification
D000880:Anthraquinones; D005295:Ferrocyanides; D007074:Immunoglobulin G; C004468:Alizarin Red S; D003035:Cobalt; C020354:hexacyanoferrate II