[Some clinical outcomes of fractional gamma-irradiation of primates].
The investigation with macaque-rhesus males aged 3 to 5 years was aimed at evaluation of the effects of 2 patterns of fractional gamma-irradiation ending up with an equal effective residual dose of 100 sGy. Irradiation was carried out on gamma-ray unit GOBO-60 with a 137Cs source and certified activity of 72 g-eq. Ra. Rectal temperature, heart rate, blood pressure and body mass were followed up over the period of 9 months. Rate of body mass gain in primates irradiated with the total gamma-dose of 250 cSv was lower as compared to the group that received the total dose of 132 cSv. Repeated irradiation 3 months later elevated the body mass gain and elevated rectal temperature considerably only in the primates that had been initially irradiated at 250 cSV Fractional gamma-irradiation had no effect on HR or BP.
A O
AO
Lazarev
Iu V
IuV
Gordeev
V P
VP
Krotov
D000818:Animals; D001794:Blood Pressure; D001831:Body Temperature; D004307:Dose-Response Relationship, Radiation; D005720:Gamma Rays / Q000009:adverse effects*; D006339:Heart Rate; D008253:Macaca mulatta; D008297:Male; D011829:Radiation Dosage; D013026:Space Flight; D018561:Space Simulation; D015430:Weight Gain