Congenital rhabdomyosarcoma, central precocious puberty, hemihypertrophy and hypophosphatemic rickets associated with epidermal nevus syndrome.
We describe a newborn girl with right-sided extended epidermal nevus, congenital rhabdomyosarcoma of the inguinal area at birth who had developed central precocious puberty, hemihypertrophy and vitamin D3-responsive hypophosphatemic rickets at the age of 14 months. Our patient demonstrates a much broader and polymorphic spectrum of organ systems involvement in epidermal nevus syndrome at a very early age of her life.
Division of Pediatric Hematology Oncology, Tehran University of Medical Sciences, Tehran, Iran. eshahgholi@gmail.com
Elham
E
Shahgholi
Mansour
M
Mollaian
Zahra
Z
Haghshenas
Malektaj
M
Honarmand
D002675:Child, Preschool; D053098:Familial Hypophosphatemic Rickets / Q000150:complications*; D005260:Female; D006801:Humans; D006984:Hypertrophy; D007223:Infant; D007231:Infant, Newborn; D054000:Nevus, Sebaceous of Jadassohn / Q000150:complications* / Q000151:congenital; D011629:Puberty, Precocious / Q000150:complications*; D012208:Rhabdomyosarcoma / Q000150:complications* / Q000151:congenital; D012878:Skin Neoplasms / Q000150:complications* / Q000151:congenital