5-formylfurfuryl esters from Duabanga grandiflora.
5-Formylfurfuryl esters, duabanganals A-D, together with sixteen known compounds, a known 5-formylfurfuryl ester, latifolinal, eight pentacyclic triterpenes, a benzofuran derivative, an ellagic acid derivative, vanillin, β-sitosterol, β-sitosterol glucoside, 3-hydroxy-4-methoxycinnamaldehyde, and 5-formylfurfurol, were isolated from the stem bark of Duabanga grandiflora. The structures of these compounds were elucidated on the basis of spectroscopic analysis. Several of these metabolites were evaluated for cytotoxic activities against six cancer cell lines.
Chulabhorn Research Institute, Bangkok, Thailand.
Wirongrong
W
Kaweetripob
Chulabhorn
C
Mahidol
Vilailak
V
Prachyawarakorn
Hunsa
H
Prawat
Somsak
S
Ruchirawat
D000475:Alkenes / Q000737:chemistry; D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D044182:Benzylisoquinolines / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D004354:Drug Screening Assays, Antitumor; D004610:Ellagic Acid / Q000737:chemistry / Q000302:isolation & purification; D004952:Esters / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D005663:Furans / Q000737:chemistry; D006367:HeLa Cells; D056945:Hep G2 Cells; D006801:Humans; D020128:Inhibitory Concentration 50; D029561:Lythraceae / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D055432:Metabolomics / Q000379:methods; D015394:Molecular Structure; D053978:Pentacyclic Triterpenes / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D024301:Plant Bark / Q000737:chemistry*; D018547:Plant Stems / Q000737:chemistry*; D012855:Sitosterols / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology
D000475:Alkenes; D000972:Antineoplastic Agents, Phytogenic; D044182:Benzylisoquinolines; D004952:Esters; D005663:Furans; D053978:Pentacyclic Triterpenes; D012855:Sitosterols; C572812:duabanganal; D004610:Ellagic Acid; C011015:lyoniside