A novel flavonoid and furoquinoline alkaloids from Vepris glomerata and their antioxidant activity.
The dichloromethane extract of the aerial part of the plant Vepris glomerata (Rutaceae) yielded a new flavonoid, which was accorded the trivial name veprisinol (1), together with four known furoquinoline alkaloids: haplopine-3,3'-dimethylallyl ether (2), anhydroevoxine (3), evoxine (4) and skimmianine (5). The structures of the compounds were established by 1D and 2D NMR spectroscopy, as well as HREIMS. Compounds 1 and 2 have strong antioxidant potential, similar to and in some instances better than ascorbic acid and can be used as beneficial additives to antioxidant supplements.
School of Chemistry, University of KwaZulu -Natal, Westville Campus, Private Bag X54001, Durban 4000, South Africa.
Joyce J
JJ
Kiplimo
Md Shahidul
MS
Islam
Neil A
NA
Koorbanally
D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D000975:Antioxidants / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D005419:Flavonoids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D011804:Quinolines / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D027821:Rutaceae / Q000737:chemistry*
D000470:Alkaloids; D000975:Antioxidants; D005419:Flavonoids; D011804:Quinolines