Chronic rhinosinusitis in children--bacteriological analysis in terms of cytological examination.
BACKGROUND
The mechanisms of inflammatory response occurring in chronic rhinosinusitis in children are multifactorial. Besides the history and a physical examination, amongst diagnostic tools there are cytological and bacteriological examinations.


OBJECTIVE
1 Determining the nature of the bacterial flora present in the nasal cavities and paranasal sinuses in children with chronic rhinosinusitis amongst patients of The Department of Paediatric Otolaryngology,Warsaw Medical University. 2 Determining the relation between bacterial strains and cytological examination of nasal mucosa in children with chronic rhinosinusitis.


METHODS
The study group included 64 patients with chronic rhinosinusitis without polyps. The control group included 30 randomly chosen children. Diagnostic tests performed in both groups were: middle meatal culture and cytological examination from the inferior nasal concha and middle meatus. Statistical analysis was accomplished with Statistica 8.0.


RESULTS



CONCLUSIONS
Damage to the respiratory epithelial surface is understood as damage to the innate immune barrier, and repeated antibiotic therapy with the subsequent repopulation of the epithelium accidentally by various bacteria can become responsible for the pathogenic effect of bacteria in chronic rhinosinusitis.
Department of Paediatric Otolaryngology, Medical University of Warsaw, Poland.
Eliza
E
Brożek-Mądry
Lechosław P
LP
Chmielik
Adam
A
Gałązka
Joanna
J
Rogulska
Magdalena
M
Frąckiewicz
Agnieszka
A
Biejat
D000293:Adolescent; D058491:Bacterial Load; D015373:Bacterial Typing Techniques; D016022:Case-Control Studies; D002452:Cell Count; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D004804:Eosinophils / Q000382:microbiology / Q000473:pathology; D004847:Epithelial Cells / Q000382:microbiology / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D009504:Neutrophils / Q000382:microbiology / Q000473:pathology; D012220:Rhinitis / Q000382:microbiology* / Q000473:pathology*; D012852:Sinusitis / Q000382:microbiology* / Q000473:pathology*