Development of a fluorescent chelating ligand for scandium ion having a Schiff base moiety.
A fluorescent ligand, 1-(2-hydroxy-3-methoxybenzaldehyde)-4-aminosalicylhydrazone (HMB-ASH), was newly designed and synthesized, and its fluorescence characteristics for metal ions were investigated in the pH range 3.0-10.5 (at a difference of 0.5 for each metal). After testing 31 different metal ions, it was found that HMB-ASH was able to emit fluorescence intensely at 512 nm with an excitation wavelength of 353 nm in the presence of Sc(3+), one of the rare earth metals, at pH values around 3.5 and 8.0. The other metal ions hardly showed fluorescence with HMB-ASH. The fluorescence was more intense at pH 8.0, and the detection limit of Sc(3+) in a buffer solution (pH 8.0) was approximately 18.8 nmol L(-1) (0.85 ppb).
Department of Analytical Chemistry, Faculty of Pharmaceutical Sciences, Toho University, Funabashi-shi, Chiba, Japan.
Hiroshi
H
Yamada
Masahito
M
Kojo
Tomomi
T
Nakahara
Kumi
K
Murakami
Takashi
T
Kakima
Hideaki
H
Ichiba
Takehiko
T
Yajima
Takeshi
T
Fukushima
D001547:Benzaldehydes / Q000737:chemistry*; D002614:Chelating Agents / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000737:chemistry*; D006835:Hydrazones / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D008024:Ligands; D057230:Limit of Detection; D012538:Scandium / Q000737:chemistry*; D012545:Schiff Bases / Q000737:chemistry*; D013050:Spectrometry, Fluorescence; D013056:Spectrophotometry, Ultraviolet
C572874:1-(2-hydroxy-3-methoxybenzaldehyde)-4-aminosalicylhydrazone; D001547:Benzaldehydes; D002614:Chelating Agents; D005456:Fluorescent Dyes; D006835:Hydrazones; D008024:Ligands; D012545:Schiff Bases; D012538:Scandium