Infection-induced hematopoiesis: a zebrafish perspective.
In response to infection, the bone marrow adjusts production of leukocyte cell types to fight off disease. In this issue of Cell Stem Cell, Hall et al. (2012) use the zebrafish model to show that nitric oxide (NO) production drives expansion of hematopoietic progenitors to produce more granulocytes.
Institut Pasteur, Unité Macrophages et Développement de l'Immunité, Département de Biologie du Développement, F-75015 Paris, France. herbomel@pasteur.fr
Philippe
P
Herbomel