Multiple keratotic papules on palm.
Porokeratotic eccrine ostial and dermal duct nevus (PEODDN) is a rare nonhereditary malformation of the eccrine duct. A relationship with linear porokeratosis is not yet established; some consider it as a rare variant of porokeratosis involving the acrosyringium, whereas others consider it a separate entity based on distinctive clinical features and histologic accentuation within ostial structures. A 7-year-old girl presented with multiple asymptomatic keratotic papules over her right palm, present since the age of 6 months. These papules were arranged in a linear distribution over the palm and middle finger of the right hand. Most of the papules were discrete. However, lesions on the middle finger coalesced to form a plaque. Histology revealed a keratin filled deep invagination of the epidermis, notable for a column of parakeratosis ("cornoid lamella"). The dermis was notable for dilated eccrine ducts and absent inflammation. Considering the clinical and histological evidence, a diagnosis of PEODDN was made. Its clinical resemblance to linear lichen planus and linear porokeratosis is discussed. Also, we provide a brief review of this rare condition.
Medical College, Kolkata, India.
Piyush
P
Kumar
Ashim Kumar
AK
Mondal
Kalyan
K
Ghosh
Avijit
A
Mondal
Ramesh Chandra
RC
Gharami
Satyendra Nath
SN
Chowdhury
D001706:Biopsy; D002648:Child; D004439:Eccrine Glands / Q000473:pathology*; D005260:Female; D006225:Hand / Q000473:pathology*; D006801:Humans; D009508:Nevus, Pigmented / Q000473:pathology*; D017499:Porokeratosis / Q000473:pathology*; D012878:Skin Neoplasms / Q000473:pathology*