Construction of aromatic [5,5] spiroketals via hypoiodite-catalyzed etherification combined in relay cascades.
An approach is developed for the synthesis of bisbenzannelated spiro[5,5]ketals via a catalytic relay reaction cascade involving a new cyclo-etherification, which is prompted by fluoride and catalyzed by the hypoiodite species generated in situ from irradiative aerobic oxidation of an iodide ion formed in the former step of the reaction cascade.
State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, P.R. China.
Wei
W
Wei
Yao
Y
Wang
Jianpeng
J
Yin
Jijun
J
Xue
Ying
Y
Li