Development of new hydrogenations of imines and benign reductive hydroaminations: zinc triflate as a catalyst.
The hydrogenation of imines to amines in the presence of catalytic amounts of zinc triflate has been demonstrated for the first time. In addition, an efficient procedure for the reductive hydroamination of alkynes to amines is presented using zinc triflate as a catalyst precursor. In both protocols a variety of different functional groups are tolerated, and the reactions proceed smoothly in high yields.
Leibniz-Institut für Katalyse e V an der Universität Rostock, Rostock, Germany.
Svenja
S
Werkmeister
Steffen
S
Fleischer
Shaolin
S
Zhou
Kathrin
K
Junge
Matthias
M
Beller
D000480:Alkynes / Q000737:chemistry; D000586:Amination; D002384:Catalysis; D055772:Green Chemistry Technology / Q000379:methods*; D006865:Hydrogenation; D007097:Imines / Q000737:chemistry*; D008698:Mesylates / Q000737:chemistry*; D010084:Oxidation-Reduction
D000480:Alkynes; D007097:Imines; D008698:Mesylates; C012077:trifluoromethanesulfonic acid