Antibacterial activity of the lactoperoxidase system combined with edible Laminaria hot-water extract as a source of halide ions.
Hot-water extracts prepared from nine out of 12 samples of dried edible Laminaria reduced the viable numbers of Aggregatibacter actinomycetemcomitans, Staphylococcus aureus, and Esherichia coli below the detection limit after incubation for 5 min when combined with lactoperoxidase, glucose oxidase, and glucose. Some extracts showed higher bactericidal activity and a higher OI(-) concentration in the assay mixture after ultrafiltration.
Food Science & Technology Institute, Morinaga Milk Industry Co, Ltd, Zama, Kanagawa, Japan. k_shin@morinagamilk.co.jp
Kouichirou
K
Shin
Manabu
M
Nakano
Koji
K
Yamauchi
Tomohiro
T
Toida
Keiji
K
Iwatsuki
D016976:Aggregatibacter actinomycetemcomitans / Q000187:drug effects; D000838:Anions; D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000302:isolation & purification; D004926:Escherichia coli / Q000187:drug effects; D005947:Glucose; D005949:Glucose Oxidase; D006219:Halogens / Q000008:administration & dosage; D007784:Lactoperoxidase / Q000494:pharmacology* / Q000627:therapeutic use; D007795:Laminaria / Q000737:chemistry*; D010936:Plant Extracts / Q000737:chemistry* / Q000494:pharmacology*; D013211:Staphylococcus aureus / Q000187:drug effects
D000838:Anions; D000900:Anti-Bacterial Agents; D006219:Halogens; D010936:Plant Extracts; D005949:Glucose Oxidase; D007784:Lactoperoxidase; D005947:Glucose