[Examination of intrathecal immunological response to Borrelia burgdorferi antigens in patients with suspected neuroborreliosis--a preliminary communication].
10 persons with suspected neuroborreliosis (in accordance with EUCALB recommendations), inpatients of Departament of Infectious Diseases and Neuroinfections were evaluated. Antibodies of IgM and IgG in CSF and serum against B. burgdorferi were tested with Western blot kits (Mikrogen, Germany). 3 of 10 tested CSF showed presence of additional bands in comparison with serum. Simultanously evaluation antibodies against B. burgdorferi in CSF and serum with Western blot kits patients with suspected neuroborreliosis is usefull to estimate intrathecal immunological response, with showing the differences between CSF and serum. Estimation of immunological response is Essentials in both classes especially in Elary phase of disease.
Klinika Chorób Zakaznych i Neuroinfekcji UM w Białymstoku.
Joanna
J
Zajkowska
Renata
R
Swierzbińska
Sławomir
S
Pancewicz
Maciej
M
Kondrusik
Sambor
S
Grygorczuk
Anna
A
Moniuszko
D000942:Antigens, Bacterial / Q000097:blood* / Q000276:immunology*; D015153:Blotting, Western; D025065:Borrelia burgdorferi / Q000276:immunology*; D004797:Enzyme-Linked Immunosorbent Assay; D005188:False Negative Reactions; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D020852:Lyme Neuroborreliosis / Q000175:diagnosis* / Q000276:immunology*; D008297:Male; D011044:Poland; D011237:Predictive Value of Tests
D000942:Antigens, Bacterial; D007074:Immunoglobulin G; D007075:Immunoglobulin M