[Association of location of deep venous thrombosis and d-dimer value in acute intracerebral hemorrhage].
OBJECTIVE
We investigated the association of the presence and the location of deep venous thrombosis (DVT) with D-dimer value in acute intracerebral hemorrhage (ICH).


METHODS
We analyzed the data regarding DVT in patients with ICH. Based on an ultrasonographic examination 2 weeks after the occurrence of ICH, the patients were divided according to the presence/absence and the location of DVT, i.e. no evidence of DVT (n-DVT), calf DVT (c-DVT), and proximal DVT (p-DVT). D-dimer value was measured 2 weeks later and compared among the groups.


RESULTS
The numbers of patients with n-DVT, c-DVT and p-DVT were 27, 19, and 2, respectively. Univariate analysis indicated that D-dimer values were significantly different between patients with n-DVT and c-DVT and between patients with n-DVT and p-DVT (p<0.05, respectively). The cut-off value for estimating the presence of DVT and p-DVT was 3.9 µg/mL and 18.5 µg/mL, respectively.


CONCLUSIONS
D-dimer value assessment after 2 weeks may be associated with the presence and the location of DVT in patients with ICH.
Department of Cerebrovascular Disease, Cerebrovascular Center and Clinical Research Institute, National Hospital Organization Kyushu Medical Center.
Toshiyasu
T
Ogata
Masahiro
M
Yasaka
Yoshiyuki
Y
Wakugawa
Takanari
T
Kitazono
Yasushi
Y
Okada
D000208:Acute Disease; D000368:Aged; D002543:Cerebral Hemorrhage / Q000150:complications*; D005260:Female; D005338:Fibrin Fibrinogen Degradation Products / Q000032:analysis*; D006801:Humans; D008297:Male; D020246:Venous Thrombosis / Q000175:diagnosis*
D005338:Fibrin Fibrinogen Degradation Products; C036309:fibrin fragment D