[Biochemical recurrence criteria after radical prostatectomy. Natural history of the disease].
OBJECTIVE
To analyze biochemical recurrence criteria, attending to different PSA-cut-points referred in the literature, and to review prostate cancer natural history.


METHODS
Review of the literature through a Medline search.


CONCLUSIONS
A PSA of 0.4 ng/ml followed by a value higher than the first, are the values that better define metastatic progression, while a PSA of 0.2 ng/ml followed by a value higher than the first could be more appropriate to define patients about to receive salvage radiotherapy. Nevertheless we need new markers in order to improve prognostic and natural history knowledge.
Programa de Investigación Traslacional en Cáncer de Próstata, Servicio de Urología, Instituto de Investigación Biomédica, Hospital Universitario Vall d'Hebron, Universidad Autónoma de Barcelona, España.
Jacques
J
Planas
Juan
J
Morote
D006801:Humans; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000097:blood*; D017430:Prostate-Specific Antigen / Q000097:blood*; D011468:Prostatectomy; D011471:Prostatic Neoplasms / Q000097:blood* / Q000601:surgery*
D017430:Prostate-Specific Antigen