Herd-specific strains of Mycoplasma bovis in outbreaks of mycoplasmal mastitis and pneumonia.
Mycoplasma bovis causes severe economic losses in livestock production, particularly on the Northern American continent and more recently also in continental Europe. The aim of the current study was to evaluate whether the recently emerging outbreaks were due to a particular clone or strain of M. bovis or whether these outbreaks are due to multiple infectious strains of M. bovis. The study is based on the analysis M. bovis isolated from cattle of herds with outbreaks of mycoplasmal mastitis or pneumonia from geographically non related parts of Switzerland. M. bovis isolates were typed by insertion sequence (IS) element analysis based upon ISMbov1 and ISMbov2 southern-blot hybridization. We observed a strong divergence of M. bovis strains among affected herds which mostly were herd specific. This argues against the assumption that a recent infiltration of a particular clone of M. bovis is the cause of the perilous emerging outbreaks. The study suggests that transmission occurs from animal to animal most probably via milk.
Institute of Veterinary Bacteriology, Vetsuisse Faculty, University of Bern, Bern, Switzerland.
Marlis
M
Aebi
Michèle
M
Bodmer
Joachim
J
Frey
Paola
P
Pilo
D000818:Animals; D002417:Cattle / Q000382:microbiology*; D004251:DNA Transposable Elements; D004269:DNA, Bacterial / Q000235:genetics; D004196:Disease Outbreaks / Q000662:veterinary*; D005260:Female; D008414:Mastitis, Bovine / Q000453:epidemiology*; D008892:Milk / Q000382:microbiology; D009175:Mycoplasma Infections / Q000453:epidemiology / Q000662:veterinary*; D045682:Mycoplasma bovis / Q000145:classification* / Q000302:isolation & purification; D011019:Pneumonia, Mycoplasma / Q000453:epidemiology / Q000662:veterinary*; D013557:Switzerland / Q000453:epidemiology
D004251:DNA Transposable Elements; D004269:DNA, Bacterial