Macular hole surgery prognostic success rates based on macular hole size.
OBJECTIVE
To evaluate the correlation between macular hole (MH) surgery outcomes and preoperative factors believed to affect surgical success rates.


METHODS
A retrospective, consecutive case series was designed to evaluate the correlation between anatomic success and preoperative factors: MH duration prior to surgery, visual acuity (VA), and MH diameter measured by optical coherence tomography (OCT) at the base and the narrowest midpoint.


RESULTS
A total of 153 eyes were enrolled. There was no significant difference in mean duration prior to surgery for MH success and failure (P = .13). Mean preoperative VA was significantly better for MH success than failure (P = .03). Mean mid-hole diameter (P < .001) and mean base-hole diameter (P < .001) were significantly less for MH success than failure. Failure rate was 0% among eyes with mid-hole diameter less than 500 microns and 14.9% with mid-hole 500 microns or greater (P < .001). Failure rate was 0% among eyes with base-hole diameter less than 500 microns, 1.4% with base-hole 500 to 999 microns, and 19.1% with base-hole of 1,000 microns or greater (P = .001).


CONCLUSIONS
Preoperative VA, mid-hole diameter, and base-hole diameter are correlated with anatomic success in MH surgery. An excellent surgical prognosis exists for MHs with mid-hole diameter less than 500 microns and base-hole less than 1,000 microns.
Department of Ophthalmology, New York University Medical Center, New York, New York, USA. amanda.saltermd@gmail.com
Amanda B
AB
Salter
Francisco A
FA
Folgar
Joseph
J
Weissbrot
Kenneth J
KJ
Wald
D058450:Endotamponade; D005260:Female; D005466:Fluorocarbons / Q000008:administration & dosage*; D006801:Humans; D008297:Male; D011379:Prognosis; D016684:Prone Position; D019591:Pseudophakia / Q000150:complications; D012167:Retinal Perforations / Q000145:classification / Q000473:pathology* / Q000601:surgery*; D012189:Retrospective Studies; D012307:Risk Factors; D013997:Time Factors; D041623:Tomography, Optical Coherence; D016896:Treatment Outcome; D014792:Visual Acuity / Q000502:physiology; D014821:Vitrectomy
D005466:Fluorocarbons; C042852:perflutren