Optical fiber LSPR biosensor prepared by gold nanoparticle assembly on polyelectrolyte multilayer.
This article provides a novel method of constructing an optical fiber localized surface plasmon resonance (LSPR) biosensor. A gold nanoparticle (NP) assembled film as the sensing layer was built on the polyelectrolyte (PE) multilayer modified sidewall of an unclad optical fiber. By using a trilayer PE structure, we obtained a monodisperse gold NP assembled film. The preparation procedure for this LSPR sensor is simple and time saving. The optical fiber LSPR sensor has higher sensitivity and outstanding reproducibility. The higher anti-interference ability for response to an antibody makes it a promising method in application as a portable immuno-sensor.
State Key Laboratory of Supramolecular Structure and Materials, Jilin University, Changchun 130012, China. yunliangshao@gmail.com
Yunliang
Y
Shao
Shuping
S
Xu
Xianliang
X
Zheng
Ye
Y
Wang
Weiqing
W
Xu
D000818:Animals; D000906:Antibodies / Q000302:isolation & purification; D015374:Biosensing Techniques / Q000379:methods*; D006046:Gold / Q000737:chemistry*; D006801:Humans; D053768:Metal Nanoparticles / Q000737:chemistry*; D055100:Optical Fibers; D015203:Reproducibility of Results; D020349:Surface Plasmon Resonance / Q000379:methods*
D000906:Antibodies; D006046:Gold