The paradox of feline coronavirus pathogenesis: a review.
Feline coronavirus (FCoV) is an enveloped single-stranded RNA virus, of the family Coronaviridae and the order Nidovirales. FCoV is an important pathogen of wild and domestic cats and can cause a mild or apparently symptomless enteric infection, especially in kittens. FCoV is also associated with a lethal, systemic disease known as feline infectious peritonitis (FIP). Although the precise cause of FIP pathogenesis remains unclear, some hypotheses have been suggested. In this review we present results from different FCoV studies and attempt to elucidate existing theories on the pathogenesis of FCoV infection.
Laboratório de Infectologia Molecular Animal (LIMA), Universidade Federal de Viçosa, Avenida Peter Henry Rolfs, s/n Campus Universitário, 36570-000 Vicosa, MG, Brazil.
Luciana Wanderley
LW
Myrrha
Fernanda Miquelitto Figueira
FM
Silva
Ethel Fernandes de Oliveira
EF
Peternelli
Abelardo Silva
AS
Junior
Maurício
M
Resende
Márcia Rogéria
MR
de Almeida