Intragastric balloon fundal or antral position affects weight loss and tolerability.
BACKGROUND
Intragastric balloons (BIB) are routinely used for weight reduction. They should be placed to the gastric fundus, as this place is believed more effective for achievement of satiety and thus weight reduction. The aim of the present study was to evaluate whether the balloon position may affect 6-month weight loss as well as first-month side-effects, i.e. nausea, vomiting, and gastroesophageal reflux.


METHODS
From a total of 158 BIB-treated obese individuals, 105 females were found eligible, since the balloon in the stomach was found upon removal in the same position (fundus or antrum) placed at the time of insertion. These subjects were divided into fundus and antral groups. Data related to obesity were recorded on day 0 and upon BIB removal, 6 months thereafter. Data related to transient side-effects (nausea, vomiting, gastroesophageal reflux) were recorded on days 0-3, 7, and weekly thereafter, for 1 month.


RESULTS
BIB placed in the antrum was found to have significantly better results on weight loss parameters, while nausea, vomiting (p = 0.02) as well as gastroesophageal reflux still remained up to the fourth week in a relation to the fundus group. Similarly, the rate of gastric distension was found significantly increased (p = 0.001) during the days 1-3 in fundus group in relation to antrum, followed by a progressive decrease in both groups.


CONCLUSIONS
Intragastric balloon placed in the antrum lead to better results in weight reduction but to longer duration of tolerability-related side-effects, i.e., nausea, vomiting, and gastroesophageal reflux.
Department of Surgery, Aristotle University of Thessaloniki, 45 Agiou Dimitriou str, 54632, Thessaloniki, Greece.
Theodossis S
TS
Papavramidis
Vasilis
V
Grosomanidis
Pyrros
P
Papakostas
Sofia
S
Penna
Katerina
K
Kotzampassi
D000328:Adult; D015992:Body Mass Index; D005260:Female; D005500:Follow-Up Studies; D015905:Gastric Balloon; D005748:Gastric Fundus; D006801:Humans; D008875:Middle Aged; D009767:Obesity, Morbid / Q000601:surgery*; D018579:Patient Selection; D011446:Prospective Studies; D011706:Pyloric Antrum; D011788:Quality of Life; D012527:Satiation; D013997:Time Factors; D016896:Treatment Outcome; D015431:Weight Loss