Asymptotic properties of mean survival estimate based on the Kaplan-Meier curve with an extrapolated tail.
Asymptotic distribution of the mean survival time based on the Kaplan-Meier curve with an extrapolated 'tail' is derived. A closed formula of the variance estimate is provided. Asymptotic properties of the estimator were studied in a simulation study, which showed that this estimator was unbiased with proper coverage probability and followed a normal distribution. An example is used to demonstrate the application of this estimator.
Department of Biostatistics, University of Michigan, Ann Arbor, MI, USA.
Qi
Q
Gong
Liang
L
Fang
D015982:Bias; D002986:Clinical Trials as Topic / Q000379:methods*; D003198:Computer Simulation; D003627:Data Interpretation, Statistical; D006801:Humans; D053208:Kaplan-Meier Estimate; D019057:Quality-Adjusted Life Years; D016019:Survival Analysis