Controlled synthesis of 3D multi-compartmental particles with centrifuge-based microdroplet formation from a multi-barrelled capillary.
Controlled synthesis of micro multi-compartmental particles using a centrifuge droplet shooting device (CDSD) is reported. Sodium alginate solutions introduced in a multi-barreled capillary form droplets at the capillary orifice under ultrahigh gravity and gelify in a CaCl(2)  solution. The size, shape, and compartmentalization of the particles are controlled. Co-encapsulation of Jurkat cells and magnetic colloids into Janus particles is demonstrated. The Janus particles present sensitive reaction toward magnetic fields, while the viability of the encapsulated cells is 91%.
Institute of Industrial Science, The University of Tokyo, Meguro-ku, Tokyo, Japan.
Kazuki
K
Maeda
Hiroaki
H
Onoe
Masahiro
M
Takinoue
Shoji
S
Takeuchi
D002498:Centrifugation / Q000295:instrumentation*; D055616:Microtechnology / Q000295:instrumentation*; D010316:Particle Size