Review article: Part one: Goal-directed resuscitation--which goals? Haemodynamic targets.
The use of appropriate resuscitation targets or end-points may facilitate early detection and appropriate management of shock. There is a fine balance between oxygen delivery and consumption, and when this is perturbed, an oxygen debt is generated. In this narrative review, we explore the value of global haemodynamic resuscitation end-points, including pulse rate, blood pressure, central venous pressure and mixed/central venous oxygen saturations. The evidence supporting the reliability of these parameters as end-points for guiding resuscitation and their potential limitations are evaluated.
Department of Intensive Care Medicine, Royal Brisbane and Women's Hospital, Brisbane, Queensland, Australia. anthony_holley@health.qld.gov.au
Anthony
A
Holley
William
W
Lukin
Jennifer
J
Paratz
Tracey
T
Hawkins
Robert
R
Boots
Jeffrey
J
Lipman
D001794:Blood Pressure / Q000502:physiology; D002496:Central Venous Pressure / Q000502:physiology; D006339:Heart Rate / Q000502:physiology; D006801:Humans; D010100:Oxygen / Q000008:administration & dosage / Q000097:blood; D010101:Oxygen Consumption / Q000502:physiology; D012151:Resuscitation / Q000379:methods*; D012771:Shock, Hemorrhagic / Q000209:etiology / Q000628:therapy*; D014463:Ultrasonography; D014947:Wounds and Injuries / Q000000981:diagnostic imaging / Q000503:physiopathology* / Q000628:therapy*
D010100:Oxygen