A selective fluorescent turn-on NIR probe for cysteine.
A selective and sensitive turn-on fluorescent NIR probe for cysteine has been developed. Cleavage of 2,4-dinitrobenzenesulfonyl (DNBS) with thiols switches the weakly fluorescent aza-BODIPY dye (λ(em) = 734 nm, Φ(f) = 0.03) to a strongly fluorescent species in the NIR region (λ(em) = 755 nm, Φ(f) = 0.14).
The Key Laboratory for Special Functional Materials, Ministry of Education, Henan University, Henan, 475004, China. xdjiang@henu.edu.cn
Xin-Dong
XD
Jiang
Jian
J
Zhang
Xiangmin
X
Shao
Weili
W
Zhao
D001557:Benzenesulfonates / Q000737:chemistry; D001896:Boron Compounds / Q000737:chemistry*; D003545:Cysteine / Q000032:analysis*; D005456:Fluorescent Dyes / Q000737:chemistry*; D013050:Spectrometry, Fluorescence; D013438:Sulfhydryl Compounds / Q000737:chemistry
C095489:4,4-difluoro-4-bora-3a,4a-diaza-s-indacene; D001557:Benzenesulfonates; D001896:Boron Compounds; D005456:Fluorescent Dyes; D013438:Sulfhydryl Compounds; C007488:dinitrobenzenesulfonic acid; D003545:Cysteine