Functional status and health-related quality of life among allogeneic transplant patients at hospital discharge: a comparison of sociodemographic, disease, and treatment characteristics.
OBJECTIVE
The purpose of this paper is to report the findings of a study of hematopoietic cell transplant patients, describing the needs of allogeneic transplant patients at the time of discharge in regard to their functional status, quality of life (QOL), and caregiver information and comparing these needs across a number of sociodemographic, disease, and treatment characteristics. The findings of this study are part of a larger mixed-methods study, representing one data time point of the larger study.


METHODS
This paper will discuss the baseline data collected at the time of discharge for 282 allogeneic transplant patients, which include sociodemographic data combined with disease, treatment, functional status, and QOL data to present a comprehensive portrait of the transplant patient at discharge.


RESULTS
Mean age was 48 years, males represented 52%, and 22% of the patients were Hispanic. The majority of the patients had acute leukemia (55%), were diagnosed within the last 3 years, and had matched unrelated (52%) transplants. The time from transplant to discharge averaged 30 days. Mean scores for QOL (scale = 1-10, with 10 = best QOL) included a low score of 5.7 for both psychological and social well-being, 6.3 for overall QOL, and 7.1 for both physical and spiritual well-being. Males had significantly higher QOL than females, as did non-Hispanics. Patients with Hodgkin's disease had significantly lower overall QOL scores.


CONCLUSIONS
Our results highlight the physical, psychological, social, and spiritual challenges which present for patients and their caregivers at the time of hospital discharge following allogeneic transplant.
Division of Nursing Research and Education, City of Hope, 1500 East Duarte Road, Duarte, CA 91010, USA. mgrant@coh.org
Marcia
M
Grant
Liz
L
Cooke
Anna Cathy
AC
Williams
Smita
S
Bhatia
Leslie
L
Popplewell
Gwen
G
Uman
Stephen
S
Forman
D000328:Adult; D000368:Aged; D017028:Caregivers / Q000523:psychology*; D003625:Data Collection; D005006:Ethnicity / Q000706:statistics & numerical data; D005260:Female; D018380:Hematopoietic Stem Cell Transplantation / Q000379:methods* / Q000523:psychology; D006689:Hodgkin Disease / Q000473:pathology / Q000628:therapy; D006801:Humans; D007938:Leukemia / Q000473:pathology / Q000628:therapy; D008297:Male; D008875:Middle Aged; D010351:Patient Discharge; D011788:Quality of Life; D012737:Sex Factors; D013997:Time Factors; D014184:Transplantation, Homologous; D055815:Young Adult