When IFN interferes with cell fate.
In this issue of Blood, de Bruin and colleagues demonstrate the ability of IFN-gamma to influence the binary cell fate choices of granulocytic-monocytic progenitors(GMPs) during viral infection, favoring monocytic over the granulocytic differentiation. This work provides mechanistic insights and a better understanding on how hematopoiesis can be remodeled during infection
Indiana University School of Medicine.
Nadia
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Carlesso