Borderline ovarian tumours.
Borderline ovarian tumours account for 10-20% of all epithelial ovarian cancer. Historically, standard primary surgery has included borderline ovarian tumours, omentectomy, peritoneal washing and multiple biopsies. As one-third of borderline ovarian tumours are diagnosed in women under the age of 40 years, fertility-sparing treatment has been more frequently used in the past 10 years. Fertility drugs are well tolerated in women with infertility after fertility-sparing surgery. Careful selection of candidates is necessary. Laparoscopic techniques can be used, but should be reserved for oncologic surgeons. This conservative treatment increases the rate of recurrence, albeit with no effect on survival. The pregnancy rate is nearly 50%, and most are achieved spontaneously. These women should be closely followed up. The question is whether this is acceptable from a gynaecologic oncologic point of view. For this reason, we will discuss recently published studies and gynaecologic oncologic concerns about the mode of fertility-sparing surgery and its consequences.
Department of Gynaecological Oncology, Oslo University Hospital, The Norwegian Radium Hospital, Nydalen, Oslo, Norway. c.g.trope@medisin.uio.no
Claes Göran
CG
Tropé
Janne
J
Kaern
Ben
B
Davidson
D002277:Carcinoma / Q000453:epidemiology / Q000473:pathology* / Q000601:surgery*; D005260:Female; D059247:Fertility Preservation; D006801:Humans; D007044:Hysterectomy / Q000009:adverse effects; D007247:Infertility, Female / Q000209:etiology / Q000517:prevention & control; D009367:Neoplasm Staging; D059351:Organ Sparing Treatments; D010051:Ovarian Neoplasms / Q000453:epidemiology / Q000473:pathology* / Q000601:surgery*; D010052:Ovariectomy / Q000009:adverse effects; D058994:Salpingectomy / Q000009:adverse effects