Noninvasive in vitro measurement of pig-blood d-glucose by using a microwave cavity sensor.
We have developed an electromagnetic microwave cavity sensor based on the resonant frequency shift for real time measurement of the glycemia in pig blood. We could determine the concentration of d-glucose in pig blood in the range of 150-550mg/dl at the resonance frequency near 4.75GHz with a bandwidth of 300MHz. The change in the d-glucose concentration in blood brings microwave reflection coefficient S(11) changes of about 6.26dB and resonance frequency shifts of about 11.25MHz due to the electromagnetic interaction between the cavity resonator and the blood filled plastic tube inserted into the cavity. This proposed system provides a unique approach for real time noninvasive and contactless glucose monitoring.
Department of Physics and Basic Science, Sogang University, Seoul, Republic of Korea.
Seungwan
S
Kim
Harutyun
H
Melikyan
Jongchel
J
Kim
Arsen
A
Babajanyan
Jung-Ha
JH
Lee
Lkhamsuren
L
Enkhtur
Barry
B
Friedman
Kiejin
K
Lee
D000818:Animals; D015374:Biosensing Techniques / Q000295:instrumentation*; D001786:Blood Glucose / Q000378:metabolism*; D058266:Dielectric Spectroscopy / Q000295:instrumentation*; D055590:Electromagnetic Phenomena; D008872:Microwaves; D023421:Models, Animal; D008991:Monitoring, Physiologic / Q000295:instrumentation* / Q000379:methods; D012680:Sensitivity and Specificity; D013552:Swine
D001786:Blood Glucose