Risk factors of surgical failure following transvaginal mesh repair for the treatment of pelvic organ prolapse.
OBJECTIVE
To identify the factors associated with pelvic organ prolapse (POP) recurrence after transvaginal mesh (TVM) repair.


METHODS
One hundred and thirteen women with symptomatic POP stage II to IV were scheduled for TVM procedures. All subjects underwent urinalyses and pelvic examination using the POP quantification (POP-Q) staging system before and after surgery.


RESULTS
Seven (6.2%) of 113 women reported POP recurrence after a mean follow-up time of 30 months. We performed a univariate analysis of patients' characteristics to identify the predictors of surgical failure after TVM. There was no difference between two groups as to body mass index, POP stage, mesh type, and preoperative urinary symptoms and urodynamic parameters (P>0.05). However, we found that uterine prolapse (P=0.016) and surgical experience (P=0.043) were two significant predictors of surgical failure. Multivariate logistic regression showed similar results.


CONCLUSIONS
Advanced uterine prolapse and lack of surgical experience were two significant predictors of failure following TVM. POP recurrence after mesh repair appears to be unlikely beyond the learning curve.
Graduate Institute of Medicine, Center of Excellence for Environmental Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
Cheng-Yu
CY
Long
Tsia-Shu
TS
Lo
Chiu-Lin
CL
Wang
Chin-Hu
CH
Wu
Cheng-Min
CM
Liu
Juin-Huang
JH
Su
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002983:Clinical Competence; D005260:Female; D006801:Humans; D016015:Logistic Models; D008875:Middle Aged; D015999:Multivariate Analysis; D056887:Pelvic Organ Prolapse / Q000601:surgery*; D012008:Recurrence; D012307:Risk Factors; D013526:Surgical Mesh / Q000009:adverse effects*; D017211:Treatment Failure; D014596:Uterine Prolapse / Q000601:surgery; D014621:Vagina / Q000601:surgery*