Arylsulfonylacetylenes as alkynylating reagents of Csp2-H bonds activated with lithium bases.
Chameleon: a new strategy for the synthesis of a wide variety of alkynyl derivatives by the reaction of substituted arylsulfonylacetylenes with organolithium species is described. The high yields, the simplicity of the experimental procedure, the broad scope of this reaction, and the formation of C(sp)-C(sp2) bonds without using transition metals are the main features of this methodology.
Departamento de Química Orgánica, Universidad Autónoma de Madrid, Cantoblanco, Spain. joseluis.garcia.ruano@uam.es
José Luis García
JL
Ruano
José
J
Alemán
Leyre
L
Marzo
Cuauhtémoc
C
Alvarado
Mariola
M
Tortosa
Sergio
S
Díaz-Tendero
Alberto
A
Fraile
D000114:Acetylene / Q000737:chemistry*; D000480:Alkynes / Q000737:chemistry; D002244:Carbon / Q000737:chemistry; D006859:Hydrogen / Q000737:chemistry; D008094:Lithium / Q000737:chemistry*; D011789:Quantum Theory; D028561:Transition Elements / Q000737:chemistry
D000480:Alkynes; D028561:Transition Elements; D002244:Carbon; D006859:Hydrogen; D008094:Lithium; D000114:Acetylene