Tolerability of combined treatment with lithium and paroxetine: 19 cases treated under open conditions.
Nineteen patients resistant to paroxetine monotherapy were treated by lithium augmentation for 6 weeks to assess tolerability. Although the addition of lithium increased the number of adverse events, none were serious. The combination of lithium and paroxetine is safe enough to warrant further investigation as a treatment for resistant depression.
Consultant in Psychological Medicine, Queen Elizabeth Hospital, Howlands, Welwyn Garden City, Hertfordshire AL7 4QH.
C J
CJ
Hawley
A G
AG
Roberts
M H
MH
Walker