Improving immunotherapy: revisiting the immunologist's little secret.
Synergy between intracellular and extracellular sensing mechanisms of the innate immune system improves adaptive immune responses to cancer vaccines and clearance of tumors.
Vaccine Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA. mail: berzofsj@mail.nih.gov
Jay A
JA
Berzofsky
D000818:Animals; D051017:Apoptosis Regulatory Proteins / Q000276:immunology* / Q000378:metabolism*; D002135:Calcium-Binding Proteins / Q000276:immunology* / Q000378:metabolism*; D019496:Cancer Vaccines / Q000276:immunology*; D005260:Female; D008297:Male; D009369:Neoplasms / Q000276:immunology*; D051616:Neuronal Apoptosis-Inhibitory Protein / Q000276:immunology* / Q000378:metabolism*; D051193:Toll-Like Receptors / Q000276:immunology* / Q000378:metabolism*
D051017:Apoptosis Regulatory Proteins; D002135:Calcium-Binding Proteins; D019496:Cancer Vaccines; C512299:Ipaf protein, mouse; C496806:Naip5 protein, mouse; D051616:Neuronal Apoptosis-Inhibitory Protein; D051193:Toll-Like Receptors