Male partial hypogonadotrophic hypogonadism with gynaecomastia and metabolic syndrome.
The causal association of childhood obesity and hypogonadotrophic hypogonadism needs to be studied to unravel the cause and effect relationship between the two conditions. The relationship of hypogonadism to the Metabolic Syndrome (MetS) remains valid even when using different definitions of MetS, and following the patients prospectively for over 10 years. This is a case of 19 years male who presented with micropenis, marked gynaecomastia and weight gain. Childhood obesity and family history of diabetes predisposed him to future MetS. Presence of micropenis reflects intrauterine hypogonadotrophic hypogonadism. Both entities exacerbated each other.
Medical Unit II, Jinnah Postgraduate Medical Centre, Karachi, Pakistan. mef.foundation@gmail.com
Tasnim
T
Ahsan
Zeenat
Z
Banu
D005500:Follow-Up Studies; D005832:Genital Diseases, Male / Q000150:complications / Q000175:diagnosis*; D006062:Gonadotropins / Q000378:metabolism; D006177:Gynecomastia / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D007006:Hypogonadism / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D008297:Male; D024821:Metabolic Syndrome / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D008687:Metformin / Q000627:therapeutic use; D010413:Penis / Q000002:abnormalities; D018570:Risk Assessment; D012720:Severity of Illness Index; D013739:Testosterone / Q000627:therapeutic use; D016896:Treatment Outcome; D014807:Vitamin D / Q000627:therapeutic use; D055815:Young Adult
D006062:Gonadotropins; D014807:Vitamin D; D013739:Testosterone; D008687:Metformin