Smaller platelet volumes associated with vascular malformations.
Various parameters in 91 adult participants with vascular malformations and 91 controls were studied. The mean of the participants' platelet volumes was 8.5 fL and that of their controls was 9.1 (P < .001). The mean of the participants' platelet mass was 2145 µL/L of blood and that of their controls was 2351 (P = .006). The other parameters studied were not significantly different than the controls. It is suggested that the lower platelet volume might be related to a compensatory mechanism to keep the total body platelet mass stable despite the increased vasculature.
Dermatology Clinic and Vascular Birthmark Service Southern California Kaiser Permanente, Pasadena, CA 91107, USA. marvinklapman@gmail.com
Marvin H
MH
Klapman
Valentina B
VB
Sosa
Gail F
GF
Mattson-Gates
Cynthia N
CN
Baker
Roman M
RM
Sydorak
Victor L
VL
Ong
Bonnie H
BH
Li
Janis F
JF
Yao
D000328:Adult; D001792:Blood Platelets / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D063847:Mean Platelet Volume; D054079:Vascular Malformations / Q000097:blood*