Effects of a lactobacilli, oligosaccharide and organic germanium intake on the immune responses of mice.
The organic germanium compound, Ge-132, has immune-modulating effects. We evaluated the symbiotic effects of Ge-132 with lactobacilli and oligosaccharide (LB/OS) on the immune responses of mice. The highest fecal IgA levels were observed in the mice receiving a low concentration of Ge-132 with LB/OS for 8 weeks. Our data suggest that LB/OS with a low concentration of Ge-132 stimulated the intestinal immunity.
Asai Germanium Research Institute Co, Ltd, Hakodate, Hokkaido, Japan. nakamura@asai-ge.co.jp
Takashi
T
Nakamura
Miki
M
Saito
Hisashi
H
Aso
D000818:Animals; D004357:Drug Synergism; D005857:Germanium / Q000276:immunology* / Q000494:pharmacology; D007109:Immunity / Q000187:drug effects*; D007070:Immunoglobulin A / Q000032:analysis; D056747:Immunomodulation; D007369:Interferon Inducers; D007422:Intestines / Q000276:immunology; D007778:Lactobacillus / Q000276:immunology*; D051379:Mice; D009844:Oligosaccharides / Q000276:immunology* / Q000494:pharmacology; D009942:Organometallic Compounds / Q000276:immunology* / Q000494:pharmacology; D011422:Propionates
D007070:Immunoglobulin A; D007369:Interferon Inducers; D009844:Oligosaccharides; D009942:Organometallic Compounds; D011422:Propionates; D005857:Germanium; C066750:propagermanium