Correlation of triglyceride level with acute coronary syndrome.
The study was aimed to find out the correlation of serum triglyceride level with acute coronary syndrome. This cross sectional study was conducted in the department of cardiology, Mymensingh Medical College Hospital, from August 2009 to May 2010. Socio-demographic characteristics, smoking habit, hypertension, serum total cholesterol level, serum HDLc, Serum LDLc, TG level were important variable considered. A total number of 100 respondents consisted of 50 cases (patient) and 50 healthy persons (control). Investigations included ECG, cardiac enzyme (troponin I), FBS and lipid profile. The data were analyzed by computer with the help of SPSS. Chi-square Test, T-test & ANOVA test were used as test of significance. The mean level of TG in acute coronary syndrome (ACS) patients (cases) was 168.2±58.0 mg/dl and in control were 141.2±45.3 mg/dl. So serum TG level is significantly higher in patients with ACS (p=0.01). In multivariate regression analysis, there was a significant association of elevated TG with risk of ACS (relative risk) is the highest, compared with the lowest quarantile = 1.011; 95% confidence interval (CI = 1.002 - 1.020; P for trend = 0.01). The relation of TG level to HDLc was a strong predictor of ACS (RR in the highest) compared with lowest quarantile = 0.02; (95% CI = 0.003 - 0.173; P for trend <0.0001). The study revealed that high level of serum triglyceride is associated with ACS. Categorization of patients with ACS on the basis of TG level may be helpful for risk stratification and management.
Mymensingh Medical College Hospital, Mymensingh, Bangladesh.
M Z
MZ
Islam
M
M
Faruque
M A
MA
Bari
M S
MS
Islam
M K
MK
Khan
N A
NA
Khan
A H
AH
Miah
M K
MK
Alam
D054058:Acute Coronary Syndrome / Q000097:blood*; D000328:Adult; D000368:Aged; D003330:Coronary Vessel Anomalies / Q000097:blood; D003430:Cross-Sectional Studies; D006801:Humans; D008875:Middle Aged; D015999:Multivariate Analysis; D014280:Triglycerides / Q000097:blood*
D014280:Triglycerides