Pulmonary metastases of a papillary adeno-carcinoma of ovary in a pregnant lady.
A 28 years young lady admitted to National Institute of Diseases of Chest and Hospital (NIDCH), Dhaka with the complaints of respiratory distress and cough for 2 months. She was in her last trimester of first pregnancy when she becomes dyspneic on exertion and at night. Gradually it increases in time and she become unable to walk when she consulted with specialists in Barisal. She was examined clinically and radiographically and found some opacity on both lung fields. She was on several antibiotics, but got no improvement. In the meantime, an emergency caesarean section was done to have a healthy baby and patient came to NIDCH for this unexplained breathlessness and cough. She was severely dyspneic, tachypnoic, cyanosed. There were bilateral coarse crepitations, bilateral opacities predominantly on both lower and middle zones of both lungs obscuring costo-phrenic angles on chest X-rays. CT scan of chest shows bilateral reticulo-nodular shadows with a homogenous opacity on right lower lung which enhances after contrast scanning. A CT guided FNAC was done from that opacity which revealed a papillary adeno-carcinoma with psammoma bodies on cytopathological study. Thereafter, to explore the primary site, thyroid gland, abdominal organs was assessed adequately and only positive finding was raised CA-125 (706 IU/ml) which was consistent with ovarian cancer. In this way, a primary ovarian carcinoma in a pregnant young lady with normal sized ovary that metastasizes to lung causing bilateral pleural effusion and lymphangitis carcinomatosa was explored. This was an unusual presentation of ovarian papillary adeno-carcinoma with cough and breathlessness at the last trimester of pregnancy in absence of any abdominal mass.
National Institute of Diseases of Chest and Hospital, Mohakhali, Dhaka, Bangladesh.
M M
MM
Rashid
M
M
Ahmed
D
D
Hossain
M G
MG
Sarwar
Y
Y
Zaman
A
A
Nigar
M R
MR
Hassan
D000231:Adenocarcinoma, Papillary / Q000150:complications / Q000556:secondary*; D000328:Adult; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications / Q000556:secondary*; D008205:Lymphangitis / Q000209:etiology; D010051:Ovarian Neoplasms / Q000473:pathology*; D016066:Pleural Effusion, Malignant / Q000209:etiology; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000473:pathology*; D011263:Pregnancy Trimester, Third