Unusual presentations of pediatric neurobrucellosis.
Neurobrucellosis is an uncommon complication of pediatric brucellosis. Acute meningitis and encephalitis are the most common clinical manifestations, however symptoms may be protean and diagnosis requires a high index of suspicion in patients from endemic areas. Diagnosis is often based on neurological symptoms, serology, and suggestive brain imaging because cerebrospinal fluid culture yields are low. Two cases of pediatric neurobrucellosis with unusual clinical and radiologic findings are presented.
Pediatric Infectious Disease Unit, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel. isolbudnik@gmail.com
Isolda
I
Budnik
Inbal
I
Fuchs
Ilan
I
Shelef
Hana
H
Krymko
David
D
Greenberg
D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002006:Brucellosis / Q000175:diagnosis* / Q000188:drug therapy* / Q000453:epidemiology*; D002648:Child; D004318:Doxycycline / Q000627:therapeutic use; D004359:Drug Therapy, Combination / Q000379:methods; D004660:Encephalitis / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy; D005260:Female; D005839:Gentamicins; D006801:Humans; D015994:Incidence; D007557:Israel; D008581:Meningitis / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy; D059906:Neuroimaging / Q000379:methods; D012293:Rifampin / Q000627:therapeutic use; D016896:Treatment Outcome; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000627:therapeutic use
D000900:Anti-Bacterial Agents; D005839:Gentamicins; D015662:Trimethoprim, Sulfamethoxazole Drug Combination; D004318:Doxycycline; D012293:Rifampin