Truncated reverse isoxazolidinyl nucleosides: a new class of allosteric HIV-1 reverse transcriptase inhibitors.
Dipartimento Farmaco-Chimico, Università degli Studi di Messina, Via S. S. Annunziata, 98168 Messina, Italy. robromeo@unime.it
Roberto
R
Romeo
Salvatore V
SV
Giofrè
Beatrice
B
Macchi
Emanuela
E
Balestrieri
Antonio
A
Mastino
Pedro
P
Merino
Caterina
C
Carnovale
Giovanni
G
Romeo
Ugo
U
Chiacchio
D009189:Avian Myeloblastosis Virus / Q000201:enzymology; D002474:Cell-Free System; D004353:Drug Evaluation, Preclinical / Q000379:methods; D054303:HIV Reverse Transcriptase / Q000037:antagonists & inhibitors* / Q000737:chemistry / Q000378:metabolism; D006801:Humans; D008826:Microbial Sensitivity Tests; D008958:Models, Molecular; D015394:Molecular Structure; D019829:Nevirapine / Q000494:pharmacology; D009705:Nucleosides / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D012194:RNA-Directed DNA Polymerase / Q000378:metabolism; D018894:Reverse Transcriptase Inhibitors / Q000737:chemistry* / Q000494:pharmacology*; D013601:T-Lymphocytes / Q000187:drug effects; D014443:Tyrosine / Q000737:chemistry / Q000378:metabolism
D009705:Nucleosides; D018894:Reverse Transcriptase Inhibitors; D014443:Tyrosine; D019829:Nevirapine; C514824:reverse transcriptase, Human immunodeficiency virus 1; D054303:HIV Reverse Transcriptase; D012194:RNA-Directed DNA Polymerase