The representations of reach endpoints in posterior parietal cortex depend on which hand does the reaching.
Neurons in the parietal reach region (PRR) have been implicated in the sensory-to-motor transformation required for reaching toward visually defined targets. The neurons in each cortical hemisphere might be specifically involved in planning movements of just one limb, or the PRR might code reach endpoints generically, independent of which limb will actually move. Previous work has shown that the preferred directions of PRR neurons are similar for right and left limb movements but that the amplitude of modulation may vary greatly. We now test the hypothesis that frames of reference and eye and hand gain field modulations will, like preferred directions, be independent of which hand moves. This was not the case. Many neurons show clear differences in both the frame of reference as well as in direction and strength of gain field modulations, depending on which hand is used to reach. The results suggest that the information that is conveyed from the PRR to areas closer to the motor output (the readout from the PRR) is different for each limb and that individual PRR neurons contribute either to controlling the contralateral-limb or else bimanual-limb control.
Center for Cognitive Neuroscience, Department of Neurobiology, Duke University Medical Center, Durham, NC 27701, USA. steve@eye-hand.wustl.edu
Steve W C
SW
Chang
Lawrence H
LH
Snyder
D000818:Animals; D006225:Hand / Q000502:physiology*; D008253:Macaca mulatta; D008297:Male; D009068:Movement / Q000502:physiology*; D010296:Parietal Lobe / Q000502:physiology*; D010775:Photic Stimulation / Q000379:methods*; D011597:Psychomotor Performance / Q000502:physiology*