Decreased inward rectification of Kir2.1 channels is a novel mechanism underlying the short QT syndrome.
Simona
S
Casini
Alex V
AV
Postma
D000818:Animals; D005260:Female; D006801:Humans; D008151:Lown-Ganong-Levine Syndrome / Q000235:genetics* / Q000503:physiopathology*; D009154:Mutation / Q000235:genetics*; D024661:Potassium Channels, Inwardly Rectifying / Q000235:genetics* / Q000502:physiology*
C489457:KCNJ2 protein, human; C489461:Kir2.1 channel; D024661:Potassium Channels, Inwardly Rectifying