[5+1] cycloaddition of C,N-cyclic N'-acyl azomethine imines with isocyanides.
A catalyst-free [5 + 1] cycloaddition reaction between isocyanides and C,N-cyclic N'-acyl azomethine imines as the "isocyanophile" leading to novel heterocycles has been developed. These reactions proceeded quickly and cleanly to afford the corresponding imin-1,3,4-oxadiazin-6-one derivatives in high to excellent yields. A wide range of C,N-cyclic N'-acyl azomethine imines and isocyanides were applicable to this reaction.
Division of Material Sciences, Graduate School of Natural Science and Technology, Kanazawa University, Kakuma, Kanazawa 920-1192, Japan. soeta@se.kanazawa-u.ac.jp
Takahiro
T
Soeta
Kaname
K
Tamura
Yutaka
Y
Ukaji
D001391:Azo Compounds / Q000737:chemistry*; D003486:Cyanides / Q000737:chemistry*; D003500:Cyclization; D007097:Imines / Q000737:chemistry*; D015394:Molecular Structure; D013882:Thiosemicarbazones / Q000737:chemistry*
D001391:Azo Compounds; D003486:Cyanides; D007097:Imines; D013882:Thiosemicarbazones; C512188:azomethine