Regression of giant pseudopolyps in inflammatory bowel disease.
Inflammatory pseudopolyps are formed in the regenerative and healing phases of ulcerated epithelium. Giant pseudopolyposis of the colon (pseudopolyp larger than 1.5 cm in size) is a very rare complication of inflammatory bowel disease and it may lead to colonic intussusception or luminal obstruction, but the more important clinical significance is that it can be endoscopically confused with a malignancy, although it is generally regarded as having no malignant potential. It has been reported that giant pseudopolyposis of the colon rarely regresses with medical management alone and this sometimes require surgical or endoscopic resection. This report illustrates 2 unusual cases of giant pseudopolyps associated with Crohn's disease and ulcerative colitis, and these giant pseudopolyps were initially confused with villous adenoma or adenocarcinoma, but they showed regression after adequate medical therapy.
Department of Gastroenterology, Daehang Hospital, Seoul, South Korea. yschoi71@dreamwiz.com
Yong Sung
YS
Choi
Jung Pil
JP
Suh
In Taek
IT
Lee
Jong Kyu
JK
Kim
Suk Hee
SH
Lee
Kyung Ran
KR
Cho
Hyun Joo
HJ
Park
Do Sun
DS
Kim
Doo Han
DH
Lee
D000230:Adenocarcinoma / Q000175:diagnosis*; D018253:Adenoma, Villous / Q000175:diagnosis*; D003093:Colitis, Ulcerative / Q000150:complications / Q000188:drug therapy; D003110:Colonic Neoplasms / Q000175:diagnosis*; D003111:Colonic Polyps / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D003424:Crohn Disease / Q000150:complications / Q000188:drug therapy; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D008875:Middle Aged; D012074:Remission Induction