Invasive pneumococcal pneumonia and respiratory virus co-infections.
To confirm whether respiratory virus infections increase susceptibility to invasive pneumococcal pneumonia, we examined data from 11 influenza seasons (1994-2005) in the United States. Invasive pneumococcal pneumonia was significantly associated with influenza and respiratory syncytial virus activities in 5 seasons. Association strength was higher when strain H3N2 was the predominant influenza A virus strain.
Emory University, Atlanta, Georgia 30322, USA.
Hong
H
Zhou
Michael
M
Haber
Susan
S
Ray
Monica M
MM
Farley
Catherine A
CA
Panozzo
Keith P
KP
Klugman
D000465:Algorithms; D060085:Coinfection / Q000453:epidemiology* / Q000382:microbiology / Q000821:virology; D005845:Georgia / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D053122:Influenza A Virus, H3N2 Subtype; D007251:Influenza, Human / Q000150:complications / Q000453:epidemiology* / Q000821:virology; D011018:Pneumonia, Pneumococcal / Q000453:epidemiology* / Q000209:etiology; D012044:Regression Analysis; D018357:Respiratory Syncytial Virus Infections / Q000453:epidemiology* / Q000209:etiology; D018113:Respiratory Syncytial Virus, Human; D013296:Streptococcus pneumoniae