A novel hemodynamic observation: worsening of tricuspid regurgitation with dobutamine infusion during a hemodynamic study.
Dobutamine has been shown to improve right ventricular contractility and cardiac output in right ventricular failure. However, the effect of dobutamine in the select group of patients with severe tricuspid regurgitation (TR) has not been described previously. We report the case of a patient with severe TR and right heart failure who developed ventricularization of right atrial pressure after dobutamine infusion. This highlights the potential worsening of TR and right heart failure in patients with TR receiving dobutamine.
Department of Medicine, Cardiovascular Section, Louisiana State University Health Sciences Center-New Orleans, USA.
Elias B
EB
Hanna
Vijayendra
V
Jaligam
D Luke
DL
Glancy
D000368:Aged; D016280:Atrial Function, Right / Q000187:drug effects*; D002316:Cardiotonic Agents / Q000008:administration & dosage / Q000009:adverse effects*; D004280:Dobutamine / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D014262:Tricuspid Valve Insufficiency / Q000503:physiopathology*
D002316:Cardiotonic Agents; D004280:Dobutamine