Acquired amegakaryocytic thrombocytopenia in a patient with occupational chemical exposure.
Acquired amegakaryocytic thrombocytopenia (AAT) is a hematologic disorder that presents as thrombocytopenia with absent megakaryocytes in the bone marrow. Causes of AAT include toxins, drugs, viral infections, systemic lupus erythematosus, and cytokine deficiencies. Patients with AAT should be followed for possible progression to aplastic anemia or myelodysplastic syndrome. We present a case of a 61-year-old woman with AAT due to occupational chemical exposure.
Divisions of 1Internal Medicine; and 2Hematology/Medical Oncology, Department of Medicine; and 3Department of Pathology, Cooper University Hospital, University of Medicine & Dentistry of New Jersey-Robert Wood Johnson Medical School, Camden, NJ.
Monaliben
M
Patel
Ankur
A
Kalra
Rakesh
R
Surapaneni
Roland
R
Schwarting
Linda
L
Devereux
D001772:Blood Cell Count; D001853:Bone Marrow / Q000473:pathology; D001855:Bone Marrow Diseases / Q000097:blood / Q000139:chemically induced*; D003902:Detergents / Q000009:adverse effects; D005260:Female; D006801:Humans; D008875:Middle Aged; D009784:Occupational Diseases / Q000097:blood*; D016273:Occupational Exposure / Q000009:adverse effects*; D010976:Platelet Count; D017713:Platelet Transfusion; D011696:Purpura, Thrombocytopenic / Q000097:blood / Q000139:chemically induced*
D003902:Detergents