A case of valproic acid-induced acute pancreatitis in tuberous sclerosis coexisting with end-stage renal disease.
Tuberous sclerosis complex (TCS) is a genetic disorder with a variable clinical presentation. It is commonly characterized by seizures, mental retardation and cutaneous angiofibromas. Renal manifestations frequently include angiomyolipomas and cysts which lead to chronic kidney disease. We report a case of valproic acid-induced acute pancreatitis in a dialysis patient affected by TCS. The case demonstrates the importance of assessing antiepileptic drug treatment in dialysis patients.
Department of Nephrology, Second University of Naples, Naples, Italy. giovi.capolongo@gmail.com
Giovanna
G
Capolongo
Miriam
M
Zacchia
Rosa Maria
RM
Pollastro
Leonardo
L
Radice
Pietro
P
Anastasio
D015746:Abdominal Pain / Q000139:chemically induced; D000208:Acute Disease; D000328:Adult; D000927:Anticonvulsants / Q000009:adverse effects*; D006801:Humans; D007676:Kidney Failure, Chronic / Q000209:etiology / Q000628:therapy*; D008297:Male; D010195:Pancreatitis / Q000139:chemically induced* / Q000175:diagnosis; D006435:Renal Dialysis / Q000009:adverse effects*; D014057:Tomography, X-Ray Computed; D014402:Tuberous Sclerosis / Q000150:complications / Q000188:drug therapy*; D014635:Valproic Acid / Q000009:adverse effects*; D014839:Vomiting / Q000139:chemically induced
D000927:Anticonvulsants; D014635:Valproic Acid