Pyridine•BrF3, the missing link for clean fluorinations of aromatic derivatives.
This work demonstrates the unique features of the never used before Py•BrF(3) complex in the field of aromatic organic fluorinations. The main disadvantage of the noncomplexed BrF(3) is the fact that usually, in addition to the desired fluorination, a parallel electrophilic aromatic bromination takes place as well. Use of the Py•BrF(3) complex reduces this electrophilic bromination, which is observed with most reagents based on fluorine and bromine [BrF].
School of Chemistry, Tel-Aviv University, Tel-Aviv 69978, Israel.
Youlia
Y
Hagooly
Shlomo
S
Rozen