Bee-honey and yogurt: a novel mixture for treating patients with vulvovaginal candidiasis during pregnancy.
OBJECTIVE
To evaluate the clinical and mycological cure rates of a novel mixture consisting of Bee-honey and yogurt compared to local antifungal agents for treating patients with vulvo-vaginal candidiasis (VVC) during pregnancy.


METHODS
This is a prospective comparative study which included 129 patients with VVC during pregnancy. The participants were allocated into study group (n = 82) who received a mixture of Bee-honey and yogurt vaginally and control group (n = 47) who received local anti-fungal agents. The Chi-square test was used to evaluate the clinical and mycological cure rates and the side-effects of both modes of therapy.


RESULTS
The clinical cure rate was significantly higher in the study than the control group (87.8 vs. 72.3%, respectively) while the mycological cure rate was higher in the control than the study group (91.5 vs. 76.9%, respectively). Both types of therapy were favorably tolerated by most of the patients. Side effects were reported only in 24.3 and 29.7% of patients in group I and II, respectively (p < 0.05).


CONCLUSIONS
The mixture of Bee-honey and yogurt produced a high clinical cure rate and a reasonable mycological cure rate. It can be used as a complementary or an alternative to antifungal agents especially in patients with VVC during pregnancy.
Department of Obstetrics and Gynecology, Sohag Faculty of Medicine, Sohag University, Sohag, Egypt, allam30@yahoo.com.
Allam M
AM
Abdelmonem
Salah M
SM
Rasheed
Abeer Sh
ASh
Mohamed
D000282:Administration, Intravaginal; D000328:Adult; D000818:Animals; D001516:Bees; D002175:Candida / Q000302:isolation & purification; D002181:Candidiasis, Vulvovaginal / Q000175:diagnosis / Q000382:microbiology / Q000628:therapy*; D005260:Female; D006722:Honey; D006801:Humans; D008875:Middle Aged; D011446:Prospective Studies; D016896:Treatment Outcome; D015014:Yogurt