Visuospatial processing in schizophrenia: does it share common mechanisms with pseudoneglect?
Schizophrenia patients demonstrate behavioural and cerebral lateralised anomalies, prompting some authors to suggest they exhibit a mild form of right unilateral neglect. To better describe and understand lateralised visuospatial anomalies in schizophrenia, three experiments were run using tasks often utilised to study visuospatial processing in healthy individuals and in neglect patients: the Behavioural Inattention Test (BIT), the manual line bisection task with and without a local cueing paradigm, the landmark task (or line bisection judgement), and the number bisection task. Although the schizophrenia patients did not exhibit the full-blown neglect syndrome, they did demonstrate marked spatial biases that differentiated them from controls on all but two tasks. More specifically, schizophrenia patients showed neither a simple perceptual deficit nor an asymmetry, but demonstrated (1) lateralised anomalies on a simple manual line bisection task; (2) unilateral attentional deficits for line bisection within a local cueing paradigm; and (3) a lateralised deficit in the visuospatial representations of numbers. Altogether, these results suggest a right hemineglect-like deficit in schizophrenia in attentional, representational, and motor-intentional processes. Yet it does not appear to be as strong a phenomenon. Indeed, it could be considered as an accentuation of the normal asymmetry in visuospatial processing.
Centre Hospitalier Le Vinatier, Bron Cedex, France. ccavezian@fo-rothschild.fr
Céline
C
Cavézian
Carine
C
Michel
Yves
Y
Rossetti
James
J
Danckert
Thierry
T
d'Amato
Mohamed
M
Saoud
D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D010468:Perceptual Disorders / Q000209:etiology / Q000503:physiopathology* / Q000523:psychology; D010775:Photic Stimulation; D012559:Schizophrenia / Q000150:complications / Q000503:physiopathology*; D012565:Schizophrenic Psychology; D013028:Space Perception / Q000502:physiology*; D014796:Visual Perception / Q000502:physiology*; D055815:Young Adult