Energetics and structural properties, in the gas phase, of trans-hydroxycinnamic acids.
We have studied the energetics and structural properties of trans-cinnamic acid (CA), o-, m-, and p-coumaric acids (2-, 3-, and 4-hydroxycinnamic acids), caffeic acid (3,4-dihydroxycinnamic acid), ferulic acid (4-hydroxy-3-methoxycinnamic acid), iso-ferulic acid (3-hydroxy-4-methoxycinnamic acid), and sinapic acid (3,5-dimethoxy-4-hydroxycinnamic acid). The experimental values of Δ(f)H(m)°(g), determined (in kJ·mol(-1)) for CA (-229.8 ± 1.9), p-coumaric acid (-408.0 ± 4.4), caffeic acid (-580.0 ± 5.9), and ferulic acid (-566.4 ± 5.7), allowed us to derive Δ(f)H(m)°(g) of o-coumaric acid (-405.6 ± 4.4), m-coumaric acid (-406.4 ± 4.4), iso-ferulic acid (-565.2 ± 5.7), and sinapic acid (-698.8 ± 4.1). From these values and by use of isodesmic/homodesmotic reactions, we studied the energetic effects of π-donor substituents (-OH and -OCH(3)) in cinnamic acid derivatives and in the respective benzene analogues. Our results indicate that the interaction between -OCH(3) and/or -OH groups in hydroxycinnamic acids takes place without significant influence of the propenoic fragment.
Instituto de Química-Física Rocasolano, CSIC, Madrid, Spain. jdavalos@iqfr.csic.es
Juan Z
JZ
Dávalos
Rebeca
R
Herrero
Antonio
A
Chana
Andrés
A
Guerrero
Pilar
P
Jiménez
José María
JM
Santiuste
D002152:Calorimetry, Differential Scanning; D003198:Computer Simulation; D003373:Coumaric Acids / Q000737:chemistry*; D005740:Gases; D015394:Molecular Structure
D003373:Coumaric Acids; D005740:Gases