Genetic defects in PRC2 components other than EZH2 are not common in myeloid malignancies.
Leonie I
LI
Kroeze
Gorica
G
Nikoloski
Pedro
P
da Silva-Coelho
Patricia
P
van Hoogen
Ellen
E
Stevens-Linders
Roland P
RP
Kuiper
Susanne
S
Schnittger
Torsten
T
Haferlach
Heike L
HL
Pahl
Bert A
BA
van der Reijden
Joop H
JH
Jansen
D002352:Carrier Proteins / Q000235:genetics*; D015331:Cohort Studies; D004268:DNA-Binding Proteins / Q000235:genetics*; D000071221:Enhancer of Zeste Homolog 2 Protein; D005787:Gene Frequency; D020022:Genetic Predisposition to Disease; D014644:Genetic Variation / Q000502:physiology; D019337:Hematologic Neoplasms / Q000235:genetics*; D006801:Humans; D009190:Myelodysplastic Syndromes / Q000235:genetics; D009196:Myeloproliferative Disorders / Q000235:genetics; D009363:Neoplasm Proteins; D009687:Nuclear Proteins / Q000235:genetics*; D063151:Polycomb Repressive Complex 2; D063146:Polycomb-Group Proteins; D020641:Polymorphism, Single Nucleotide; D012097:Repressor Proteins / Q000235:genetics*; D014157:Transcription Factors / Q000235:genetics*
D002352:Carrier Proteins; D004268:DNA-Binding Proteins; C491488:EED protein, human; D009363:Neoplasm Proteins; D009687:Nuclear Proteins; D063146:Polycomb-Group Proteins; D012097:Repressor Proteins; C430461:SUZ12 protein, human; D014157:Transcription Factors; C498409:EZH2 protein, human; D000071221:Enhancer of Zeste Homolog 2 Protein; D063151:Polycomb Repressive Complex 2