Common signaling networks characterize leukemia-initiating cells in acute myeloid leukemia.
Identification and characterization of leukemia-initiating cells (LICs) is important to understand leukemogenesis and develop novel therapies for leukemia. In this issue of Cell Stem Cell, Gibbs et al. (2012) demonstrate that common active signaling pathways in LICs may be targeted to treat acute myeloid leukemia.
Molecular Medicine and Gene Therapy, Lund Stem Cell Center, Lund University Hospital, BMC A12, 221 84 Lund, Sweden.
Kenichi
K
Miharada
Stefan
S
Karlsson