Palladium-catalyzed direct hydroxymethylation of aryl halides and triflates with potassium acetoxymethyltrifluoroborate.
Suzuki-Miyaura cross-coupling reactions of aryl halides and triflates with potassium acetoxymethyltrifluoroborate afforded the corresponding aryl and heteroaryl methanol products in moderate to excellent yields.
Graduate School of Pharmaceutical Sciences, University of Tokyo, 7-3-1 Hongo, Tokyo 113-0033, Japan.
Norio
N
Murai
Masahiro
M
Yonaga
Keigo
K
Tanaka
D017605:Bromine Compounds / Q000737:chemistry*; D002384:Catalysis; D017606:Chlorine Compounds / Q000737:chemistry*; D006865:Hydrogenation; D008024:Ligands; D008698:Mesylates / Q000737:chemistry*; D008745:Methylation; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*; D011188:Potassium
D017605:Bromine Compounds; D017606:Chlorine Compounds; D008024:Ligands; D008698:Mesylates; D009942:Organometallic Compounds; C572277:potassium acetoxymethyltrifluoroborate; D010165:Palladium; C012077:trifluoromethanesulfonic acid; D011188:Potassium