Algicidal activity of glycerolipids from brown alga Ishige sinicola toward red tide microalgae.
Bioassay-guided fractionation of a methanol extract of the brown alga, Ishige sinicola, led to the isolation of five algicidal compounds. Their structures were determined to be α-monoglycerides of eicosa-5Z,8Z,11Z,14Z-tetraenoic (arachidonic) acid, octadeca-6Z,9Z,12Z,15Z-tetraenoic acid, linoleic acid and oleic acid, and 1-O-palmitoyl-3-O-(6-sulfo-α-D-quinovopyranosyl)-sn-glycerol on the basis of spectroscopic data and a comparison with the data in the literature. These glycerolipids showed moderate-to-high cell lysis activity against the red tide microalgal species, Heterosigma akashiwo, Karenia mikimotoi and Alexandrium catenella, at a concentration of 20 µg/mL.
Faculty of Fisheries, Nagasaki University, Nagasaki, Japan.
Shotaro
S
Hirao
Kenji
K
Tara
Kazuyoshi
K
Kuwano
Junji
J
Tanaka
Fumito
F
Ishibashi
D004305:Dose-Response Relationship, Drug; D005989:Glycerides / Q000633:toxicity*; D057097:Harmful Algal Bloom / Q000187:drug effects*; D058086:Microalgae / Q000187:drug effects*; D000459:Phaeophyceae / Q000737:chemistry*; D013057:Spectrum Analysis
D005989:Glycerides