The precision of PiCCO® measurements in hypothermic post-cardiac arrest patients.
The aim of the present study was to determine the precision of the PiCCO(®) system for post-cardiac arrest patients who underwent therapeutic hypothermia. The precision of the measurements for cardiac output, global end-diastolic volume, extravascular lung water and the pulmonary vascular permeability index was assessed using the least significant change; this was regarded as precise when less than 15%. A total of 462 measurement sets were prospectively performed on 88 patients following successful resuscitation after cardiac arrest. Using the mean value of three injections for a measurement, the least significant change for the cardiac output, global end-diastolic volume, extravascular lung water and pulmonary vascular permeability index measurements were found to be 7.8%, 8.5%, 7.8% and 12.1%, respectively. No significant differences between hypothermia (n=150) and non-hypothermia (n=312) were found. The PiCCO-derived variables were found to be precise for post-cardiac arrest patients even under conditions of varying body temperature.
Department of Emergency and Critical Care Medicine, Nippon Medical School, Tokyo, Japan. t-tagami@nms.ac.jp
T
T
Tagami
S
S
Kushimoto
R
R
Tosa
M
M
Omura
J
J
Hagiwara
H
H
Hirama
H
H
Yokota
D000368:Aged; D000369:Aged, 80 and over; D002199:Capillary Permeability; D002302:Cardiac Output; D015633:Extravascular Lung Water; D005260:Female; D006323:Heart Arrest / Q000503:physiopathology*; D006801:Humans; D007036:Hypothermia, Induced; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D013318:Stroke Volume; D013815:Thermodilution