Infantile  systemic  hyalinosis.
Infantile systemic hyalinosis is a rare disorder characterized by widespread deposition of hyaline. They usually present with skin lesions, joint contractures, and intractable diarrhea. We report a 2 year 4 month old boy with growth retardation, typical  facial appearance, gingival enlargement, generalized stiff skin, joint contractures, and intermittent diarrhea. Skin biopsy revealed deposition of hyaline.
Department of Pediatric Medicine, Institute of Child Health, Kolkata 17, India. dr.prabhas@yahoo.co.in
Prabhas Prasun
PP
Giri
Rajesh
R
Raushan
Apurba
A
Ghosh
Priyankar
P
Pal
D002675:Child, Preschool; D005500:Follow-Up Studies; D006801:Humans; D057770:Hyaline Fibromatosis Syndrome / Q000175:diagnosis* / Q000628:therapy; D008297:Male; D012867:Skin / Q000473:pathology*