Three new steroidal glycosides from roots of Reineckia carnea.
Two new spirostanols and a new furostanol, reinocarnoside A (1), B (2) and C (3), were isolated from the roots of Reineckia carnea, together with two known compounds, (25S)-1β,3β,4β-trihydroxyspirostan-5β-yl-O-β-D-glucopyranoside (4), kitigenin-5β-O-β-D-glucopyranoside (5). The structures of three new compounds were elucidated by spectroscopic methods including 1-D NMR, 2-D NMR and MS spectrums, and their anticancer activities were evaluated by MTT method.
Hubei Key Laboratory of Natural Products Research and Development, College of Chemistry and Life Science, China Three Gorges University, Yichang 443002, P.R. China.
Qian
Q
Wang
Qune
Q
Hou
Zhiyong
Z
Guo
Kun
K
Zou
Yanhong
Y
Xue
Nianyu
N
Huang
Fan
F
Cheng
Yuan
Y
Zhou
D000970:Antineoplastic Agents / Q000494:pharmacology*; D006027:Glycosides / Q000032:analysis* / Q000302:isolation & purification / Q000494:pharmacology; D056945:Hep G2 Cells / Q000187:drug effects; D006801:Humans; D019668:Liliaceae / Q000737:chemistry*; D061986:MCF-7 Cells / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D015394:Molecular Structure; D010936:Plant Extracts / Q000032:analysis* / Q000302:isolation & purification / Q000494:pharmacology; D018517:Plant Roots / Q000737:chemistry*; D013150:Spirostans / Q000032:analysis* / Q000302:isolation & purification / Q000494:pharmacology; D013261:Sterols / Q000032:analysis* / Q000302:isolation & purification / Q000494:pharmacology; D013778:Tetrazolium Salts; D013844:Thiazoles
D000970:Antineoplastic Agents; D006027:Glycosides; D010936:Plant Extracts; D013150:Spirostans; D013261:Sterols; D013778:Tetrazolium Salts; D013844:Thiazoles; C574436:furostanol glycoside; C022616:thiazolyl blue