Regulation of DNA glycosylases and their role in limiting disease.
This review will present a current understanding of mechanisms for the initiation of base excision repair (BER) of oxidatively-induced DNA damage and the biological consequences of deficiencies in these enzymes in mouse model systems and human populations.
Center for Research on Occupational and Environmental Toxicology, Oregon Health & Science University, 3181 SW Sam Jackson Park Rd, Portland, Oregon 97239 - 3098, USA.
Harini
H
Sampath
Amanda K
AK
McCullough
R Stephen
RS
Lloyd
D000818:Animals; D045647:DNA Glycosylases / Q000235:genetics*; D004260:DNA Repair / Q000235:genetics*; D004195:Disease Models, Animal; D005786:Gene Expression Regulation; D006801:Humans; D051379:Mice
D045647:DNA Glycosylases