A study of the association of micro-albuminuria and C-reactive protein (CRP) in normotensive diabetic and hypertensive diabetic patients.
Diabetes mellitus and hypentension are known to increase markers of inflammation, ie, C-reactive protein (CRP), especially when they develop micro-albuminuria. A total of 60 patients (23 males and 37 females), all having diabetes mellitus, according to ADA criteria and micro-albuminuria in morning spot urine sample were recruited in the study. They were randomised into 2 groups, each comprising 30 patients. Group A comprised hypertensive and Group B normotensive individuals. CRP level was assessed in all patients by routine assay. CRP value of >3 mg/l was observed in 56.66% patients of group A and 23.33% patients of group B (p=0.018). So diabetic patients with micro-albuminuria had more frequent association with increased marker of inflammation in the hypertensive group compared to those without hypertension.
RG Kar Medical College and Hospital, Kolkata 700004.
Indranil
I
Ray
Ananta K
AK
Datta
Pradip
P
Mukhopadhyay
Subhabrata
S
Roy
M R
MR
Khandakar
Animesh
A
Maity
D000328:Adult; D000367:Age Factors; D000419:Albuminuria / Q000175:diagnosis* / Q000378:metabolism / Q000503:physiopathology; D015415:Biomarkers; D001795:Blood Pressure Determination; D002097:C-Reactive Protein / Q000378:metabolism*; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000378:metabolism / Q000503:physiopathology; D003928:Diabetic Nephropathies / Q000175:diagnosis* / Q000378:metabolism / Q000503:physiopathology; D042241:Early Diagnosis; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000378:metabolism / Q000503:physiopathology; D007249:Inflammation / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D012307:Risk Factors
D015415:Biomarkers; D002097:C-Reactive Protein