[Nephroprotection diabetes mellitus type 2: lessons from the ADVANCE trial].
Based on the results of the ADVANCE study, the article considers the issues of medication nephroprotection in patients with type 2 diabetes mellitus,  including patients with uncontrolled arterial hypertension. Potentials for use of fixed combination of perindopril  +  indapmide, which provides therapeutic effect at all stages of renal continuum, are discussed. It is established that improved control of blood pressure by combination of perindopril  +  indapmide leads to a significant decrease in mortality in DM 2 patients.
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D000959:Antihypertensive Agents / Q000008:administration & dosage; D003924:Diabetes Mellitus, Type 2 / Q000150:complications* / Q000188:drug therapy*; D003928:Diabetic Nephropathies / Q000188:drug therapy* / Q000517:prevention & control*; D004359:Drug Therapy, Combination; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000517:prevention & control; D007190:Indapamide / Q000008:administration & dosage*; D020913:Perindopril / Q000008:administration & dosage*; D016032:Randomized Controlled Trials as Topic
D000959:Antihypertensive Agents; D007190:Indapamide; D020913:Perindopril