title: Nickel(0)-catalyzed Heck cross-coupling via activation of aryl C-OPiv bonds.
abstract: Using a Ni(dppf) catalyst generated in situ, Heck cross-coupling of aryl pivalates with a variety of olefin partners has been accomplished. This method represents one of the first examples of a C-C cross-coupling via activation of a strong C-O bond with a nonorganometallic coupling partner. It enables the transformation of phenol-based substrates into styrenyl products without generation of a halogenated byproduct or the use of expensive triflate groups.
authors.affiliation: Department of Chemistry and Biochemistry, University of Delaware, Newark, Delaware 19716, USA.
authors.forename: Andrew R
authors.initials: AR
authors.lastname: Ehle
authors.forename: Qi
authors.initials: Q
authors.lastname: Zhou
authors.forename: Mary P
authors.initials: MP
authors.lastname: Watson