title: Side branch fractional flow reserve measurements after main vessel stenting: a Nordic-Baltic Bifurcation Study III substudy.
abstract: OBJECTIVE
  The substudy was performed to evaluate the acute and eight-month follow-up effect of final kissing balloon dilatation (FKBD) on fractional flow reserve (FFR) in the side branch (SB) after main vessel (MV) stenting.
  
  
  RESULTS
  We included 75 patients in the Nordic-Baltic Bifurcation Study III FFR substudy: 42 in the FKBD group and 33 in the no-FKBD group. Complete angiographic and FFR eight-month follow-up was obtained in 25 (60%) patients in the FKBD group and 21 (63%) patients in the no-FKBD group. In the FKBD group the post-PCI mean SB FFR was significantly higher compared to the no-FKBD group (0.92 vs. 0.85, respectively; p=0.011). No significant difference in FFR value between treatments was detected at eight-month follow-up (0.91 vs. 0.87; p=0.19). There were no significant changes in mean SB FFR during the follow-up period (0.92 vs. 0.91; p=0.80) in the FKBD group and (0.87 vs. 0.87; p=0.91) in the no-FKBD group.
  
  
  CONCLUSIONS
  FKBD in simple stenting of bifurcation lesions improved acute functional outcome in SB compared to leaving the SB jailed. No significant difference was detected at follow-up. In both groups there was no significant functional late loss during follow-up. Thus, both strategies were equally effective in ensuring that side branch jailing would not cause ischaemia in the long term.
authors.affiliation: Latvian Center of Cardiology, Paul Stradins Clinical Hospital, Riga, Latvia. ikumsars@inbox.lv
authors.forename: Indulis
authors.initials: I
authors.lastname: Kumsars
authors.forename: Inga
authors.initials: I
authors.lastname: Narbute
authors.forename: Leif
authors.initials: L
authors.lastname: Thuesen
authors.forename: Matti
authors.initials: M
authors.lastname: Niemelä
authors.forename: Terje K
authors.initials: TK
authors.lastname: Steigen
authors.forename: Kari
authors.initials: K
authors.lastname: Kervinen
authors.forename: Dace
authors.initials: D
authors.lastname: Sondore
authors.forename: Niels R
authors.initials: NR
authors.lastname: Holm
authors.forename: Jens F
authors.initials: JF
authors.lastname: Lassen
authors.forename: Evald H
authors.initials: EH
authors.lastname: Christiansen
authors.forename: Michael
authors.initials: M
authors.lastname: Maeng
authors.forename: Sanda
authors.initials: S
authors.lastname: Jegere
authors.forename: Dace
authors.initials: D
authors.lastname: Juhnevica
authors.forename: Andrejs
authors.initials: A
authors.lastname: Erglis
mesh_terms: D000368:Aged; D015906:Angioplasty, Balloon, Coronary / Q000295:instrumentation* / Q000379:methods*; D017023:Coronary Angiography; D003324:Coronary Artery Disease / Q000503:physiopathology / Q000628:therapy*; D003330:Coronary Vessel Anomalies / Q000503:physiopathology*; D003331:Coronary Vessels / Q000503:physiopathology*; D003718:Denmark; D054855:Drug-Eluting Stents; D005260:Female; D005387:Finland; D005500:Follow-Up Studies; D006801:Humans; D007844:Latvia; D008297:Male; D008875:Middle Aged; D009664:Norway; D012039:Regional Blood Flow / Q000502:physiology*; D012189:Retrospective Studies; D020123:Sirolimus; D016896:Treatment Outcome
chemical_list: D020123:Sirolimus