title: The 30-year cardiovascular risk profile of South Africans with diagnosed diabetes, undiagnosed diabetes, pre-diabetes or normoglycaemia: the Bellville, South Africa pilot study.
abstract: The aim of this pilot study was to assess the 30-year risk for cardiovascular disease (CVD) in the South Africa population of mixed-ancestry in individuals with non-diabetic hyperglycaemia, and undiagnosed and self-reported diabetes. Participants were drawn from an urban community of the Bellville South suburb of Cape Town. In total, 583 subjects without a history of CVD were eligible for lifetime CVD risk estimation. Gender-specific prediction for CVD risk was calculated using the 30-year CVD interactive risk calculator. High CVD risk (> 20%) was evident in normoglycaemic and younger subjects (under 35 years). The significant predictors of CVD were sibling history of diabetes, and triglyceride, low-density lipoprotein cholesterol and glycated haemoglobin levels (p < 0.001). The high lifetime risk in normoglycaemic and younger subjects may be considered a warning that CVD might take on epidemic proportions in the near future in this country. We recommend the inclusion of education on CVD in school and university curricula.
authors.affiliation: Department of Bio-Medical Sciences, Faculty of Health and Wellness Science, Cape Peninsula University of Technology, Cape Town, South Africa.
authors.forename: T E
authors.initials: TE
authors.lastname: Matsha
authors.forename: M S
authors.initials: MS
authors.lastname: Hassan
authors.forename: M
authors.initials: M
authors.lastname: Kidd
authors.forename: R T
authors.initials: RT
authors.lastname: Erasmus
mesh_terms: D002318:Cardiovascular Diseases / Q000453:epidemiology; D003920:Diabetes Mellitus; D006801:Humans; D006943:Hyperglycemia; D010865:Pilot Projects; D012307:Risk Factors; D013019:South Africa / Q000453:epidemiology