title: The epidemiology and etiology of influenza-like illness in Chinese children from 2008 to 2010.
abstract: Influenza-like illness can be caused by a wide range of respiratory viruses. In order to investigate the epidemiology of viral pathogens related to influenza-like illness in children of Wuhan, the largest city in central China, throat swab samples were collected from 1,472 young patients, from July 2008 to June 2010, before and after the occurrence of the 2009 pandemic influenza A (H1N1) virus (pH1N1). It was found that 923 patients (62.7%) were positive for at least 1 virus and 90 patients (9.8%) were detected for multiple (≥2) respiratory viruses by real-time PCR detection of 16 viruses. Seasonal influenza A virus was the predominant pathogen among all the 16 viruses with a positive rate of 13.3% (196/1,472), which was followed by pH1N1 (159/1,472). It was also noted that the viral distribution pattern in Wuhan changed upon the introduction of the pH1N1 virus.
authors.affiliation: Wuhan Centers for Disease Prevention and Control, Wuhan, China.
authors.forename: Jinsong
authors.initials: J
authors.lastname: Peng
authors.forename: Wenhua
authors.initials: W
authors.lastname: Kong
authors.forename: Deyin
authors.initials: D
authors.lastname: Guo
authors.forename: Manqing
authors.initials: M
authors.lastname: Liu
authors.forename: Ying
authors.initials: Y
authors.lastname: Wang
authors.forename: Honghao
authors.initials: H
authors.lastname: Zhu
authors.forename: Beibei
authors.initials: B
authors.lastname: Pang
authors.forename: Xiaoping
authors.initials: X
authors.lastname: Miao
authors.forename: Bin
authors.initials: B
authors.lastname: Yu
authors.forename: Tongyong
authors.initials: T
authors.lastname: Luo
authors.forename: Quan
authors.initials: Q
authors.lastname: Hu
authors.forename: Dunjin
authors.initials: D
authors.lastname: Zhou
mesh_terms: D000293:Adolescent; D044466:Asian People; D002648:Child; D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007251:Influenza, Human / Q000453:epidemiology* / Q000821:virology*; D008297:Male; D009975:Orthomyxoviridae / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification*; D010614:Pharynx / Q000821:virology; D016133:Polymerase Chain Reaction; D015995:Prevalence