title: Abdominal obesity is associated with a lower ankle-brachial index in women with polycystic ovary syndrome.
abstract: Polycystic ovary syndrome (PCOS) was linked to increased lifetime risk of cardiovascular disease. A low ankle-brachial index (ABI) is associated with accelerated atherosclerosis. The ABI value and the associated conditions in women with PCOS were searched in the present study. The ABI was measured using a handheld Doppler device and calculated using both standard and modified definitions. Women with PCOS (n = 103, mean age = 24.9 ± 5.9 years) had a mean ABI of 1.10 ± 0.10. A low ABI (≤0.9) was 2.9% and 14.6% using the standard and modified definitions, respectively. Mean ABI correlated negatively to body weight, BMI, waist circumference, waist-to-hip ratio, and hematocrit. Logistic regression analysis revealed higher waist-to-hip ratio as independently associated with a lower ABI. Frequency of ABI ≤0.9 in PCOS was lower than the general population. However, increased waist-to-hip ratio was a predictor of a lower ABI value.
authors.affiliation: Department of Internal Medicine, Gulhane School of Medicine, Ankara, Turkey.
authors.forename: Mustafa Inanc
authors.initials: MI
authors.lastname: Dogan
authors.forename: Ilker
authors.initials: I
authors.lastname: Tasci
authors.forename: Fatih
authors.initials: F
authors.lastname: Bulucu
authors.forename: Aydogan
authors.initials: A
authors.lastname: Aydogdu
authors.forename: Ramazan
authors.initials: R
authors.lastname: Acar
authors.forename: Temel
authors.initials: T
authors.lastname: Ceyhan
authors.forename: Bayram
authors.initials: B
authors.lastname: Koc
authors.forename: Orhan
authors.initials: O
authors.lastname: Demir
authors.forename: Mustafa
authors.initials: M
authors.lastname: Gezer
authors.forename: Kenan
authors.initials: K
authors.lastname: Saglam
mesh_terms: D000293:Adolescent; D000328:Adult; D055109:Ankle Brachial Index; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D056128:Obesity, Abdominal / Q000150:complications* / Q000503:physiopathology*; D011085:Polycystic Ovary Syndrome / Q000150:complications* / Q000503:physiopathology*; D055815:Young Adult