title: Three new monomeric indole alkaloids from the roots of Catharanthus roseus.
abstract: Two new alkaloid glycosides (1 and 2) and a new monomeric indole alkaloid (3), together with 13 known ones (4-16), were isolated from the roots of Catharanthus roseus. The structures of new compounds were elucidated on the basis of the spectroscopic methods. The absolute configuration of compound 3 was established by the modified Mosher's method.
authors.affiliation: Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing, 210009, China.
authors.forename: Chun-Hua
authors.initials: CH
authors.lastname: Wang
authors.forename: Guo-Cai
authors.initials: GC
authors.lastname: Wang
authors.forename: Ying
authors.initials: Y
authors.lastname: Wang
authors.forename: Xiao-Qi
authors.initials: XQ
authors.lastname: Zhang
authors.forename: Xiao-Jun
authors.initials: XJ
authors.lastname: Huang
authors.forename: Wen-Cai
authors.initials: WC
authors.lastname: Ye
mesh_terms: D030008:Catharanthus / Q000737:chemistry*; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification*; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification*; D026121:Indole Alkaloids / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D018517:Plant Roots / Q000737:chemistry
chemical_list: C571054:10-hydroxycathafoline 10-O-alpha-L-arabinopyranoside; C571052:10-hydroxydeformodihydropseudoakuammigine-10-O-alpha-L-arabinopyranoside; C571053:15(S)-hydroxy-14,15-dihydrovindolinine; D004365:Drugs, Chinese Herbal; D006027:Glycosides; D026121:Indole Alkaloids