title: The effect of steroid injection of the tongue base on reducing postoperative airway obstruction in cleft palate repair.
abstract: Upper airway obstruction (UAO) is a well known complication of cleft palate repair. The aim of this study was to evaluate the efficacy of local tongue base steroid injection in preventing or reducing the lingual oedema that can cause UAO following palatoplasty. Thirty children with unilateral complete cleft palate were included. They were randomly divided into two equal groups. Children in group I received intravenous dexamethasone whilst children in group II received both intravenous dexamethasone and local betamethasone injected at the tongue base. Both groups underwent the same technique of palatoplasty, postoperative breathing was assessed and UAO was rated as mild, moderate or severe. Postoperative UAO developed in six cases (40%) in group I and in two cases (13%) in group II. In group I, it was mild in three cases, moderate in one case, and severe in two cases. In group II, it was mild in one case and moderate in another case. Despite the differences in the number and severity of the condition in both groups, comparison was statistically insignificant. Local steroid injection of the tongue base during cleft palate surgery reduced the incidence and severity of post-palatoplasty UAO.
authors.affiliation: Department of Otolaryngology, Faculty of Medicine, Cairo University, Egypt. mosabeez@yahoo.com
authors.forename: M
authors.initials: M
authors.lastname: Abdel-Aziz
authors.forename: A
authors.initials: A
authors.lastname: Ahmed
authors.forename: N
authors.initials: N
authors.lastname: Naguib
authors.forename: M I
authors.initials: MI
authors.lastname: Abdel-Khalik
mesh_terms: D000402:Airway Obstruction / Q000145:classification / Q000517:prevention & control*; D000768:Anesthesia, General; D018685:Anesthetics, Inhalation / Q000008:administration & dosage; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage*; D001623:Betamethasone / Q000008:administration & dosage*; D002675:Child, Preschool; D002972:Cleft Palate / Q000601:surgery*; D003907:Dexamethasone / Q000008:administration & dosage; D004487:Edema / Q000517:prevention & control; D005260:Female; D005938:Glucocorticoids / Q000008:administration & dosage*; D006801:Humans; D007223:Infant; D007273:Injections, Intramuscular; D007275:Injections, Intravenous; D007442:Intubation, Intratracheal / Q000379:methods; D008297:Male; D008738:Methyl Ethers / Q000008:administration & dosage; D011183:Postoperative Complications / Q000145:classification / Q000517:prevention & control*; D019651:Plastic Surgery Procedures / Q000379:methods; D012119:Respiration; D012135:Respiratory Sounds / Q000145:classification; D000077149:Sevoflurane; D013524:Surgical Flaps / Q000145:classification; D014059:Tongue / Q000187:drug effects; D014060:Tongue Diseases / Q000517:prevention & control
chemical_list: D018685:Anesthetics, Inhalation; D000893:Anti-Inflammatory Agents; D005938:Glucocorticoids; D008738:Methyl Ethers; D000077149:Sevoflurane; D003907:Dexamethasone; D001623:Betamethasone