title: A rare case of the coexistence of ovarian clear cell carcinoma, mucinous cystadenoma, and endometriosis in the same ovary.
abstract: Clear cell carcinomas and endometrioid carcinomas are associated with endometriosis. The association of clear cell carcinomas with mucinous lesions has only been reported infrequently, and with mucinous cystadenoma has been rarely reported. This is the second reported case of the coexistence of ovarian clear cell carcinoma, mucinous cystadenoma, and endometriosis in the same ovary. A 57-year-old woman presented with lower abdominal pain for three weeks. Ultrasonography revealed a 16 x 14 x 10 cm mass in the left ovary with solid and cystic components. Hysterectomy and bilateral salpingo-oophorectomy were performed. Histopathological examination of the left ovary revealed the presence of clear cell carcinoma, mucinous cystadenoma, and endometriosis. Continuity between the areas of mucinous epithelium and clear cell carcinoma were noted; this may suggest that clear cell carcinoma may arise from endometriosis or mucinous cystic tumors.
authors.affiliation: Department of Pathology, Tri-Service General Hospital and National Defense Medical Center, Taipei, Taiwan.
authors.forename: H S
authors.initials: HS
authors.lastname: Shang
authors.forename: T K
authors.initials: TK
authors.lastname: Chao
authors.forename: G Z
authors.initials: GZ
authors.lastname: Wu
authors.forename: C P
authors.initials: CP
authors.lastname: Yu
mesh_terms: D018262:Adenocarcinoma, Clear Cell / Q000209:etiology / Q000473:pathology*; D018291:Cystadenoma, Mucinous / Q000150:complications / Q000473:pathology*; D004715:Endometriosis / Q000150:complications / Q000473:pathology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D010049:Ovarian Diseases / Q000473:pathology*; D010051:Ovarian Neoplasms / Q000209:etiology / Q000473:pathology*