title: Rare coding SNP in DZIP1 gene associated with late-onset sporadic Parkinson's disease.
abstract: An association between a rare, coding, non-synonymous SNP variant in the gene DZIP1 and Parkinson's disease was found, based on an analysis of the existing NGRC genome-wide association study dataset. The statistical analysis utilized the hypothesis-rich, targeted search unbiased assessment approach, rather than the hypothesis-free, genome-wide agnostic search paradigm. The association of DZIP1 with Parkinson's disease is discussed in the context of a Parkinson's disease stem-cell ageing theory.
authors.forename: André X C N
authors.initials: AX
authors.lastname: Valente
authors.forename: Joo H
authors.initials: JH
authors.lastname: Shin
authors.forename: Abhijit
authors.initials: A
authors.lastname: Sarkar
authors.forename: Yuan
authors.initials: Y
authors.lastname: Gao