title: [Resolution of racemic ortho-isobornylphenol into enantiomers and evaluation of their antioxidant activity].
abstract: The resolution of the racemic ortho-isobornylphenol into enantiomers via diastereomeric camphanates was carried out. The absolute configuration ofchiral centers of synthesized compounds was established by the single crystal X-ray diffraction method. Antioxidant activity and membrane protective properties of individual enantiomers were studied on the model of H2O2-induced hemolysis of red blood cells.
authors.forename: E V
authors.initials: EV
authors.lastname: Buravlev
authors.forename: I Iu
authors.initials: IIu
authors.lastname: Chukchieva
authors.forename: O G
authors.initials: OG
authors.lastname: Shevchenko
authors.forename: K Iu
authors.initials: KIu
authors.lastname: Suponitskiĭ
authors.forename: A V
authors.initials: AV
authors.lastname: Kuchin
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000737:chemistry* / Q000494:pharmacology*; D001892:Camphanes / Q000138:chemical synthesis* / Q000494:pharmacology*; D002462:Cell Membrane / Q000187:drug effects; D018360:Crystallography, X-Ray; D004912:Erythrocytes / Q000187:drug effects; D006454:Hemoglobins / Q000737:chemistry; D006461:Hemolysis; D006861:Hydrogen Peroxide / Q000737:chemistry; D051379:Mice; D010084:Oxidation-Reduction; D010636:Phenols / Q000737:chemistry* / Q000494:pharmacology*; D013237:Stereoisomerism
chemical_list: D000975:Antioxidants; D001892:Camphanes; D006454:Hemoglobins; D010636:Phenols; D006861:Hydrogen Peroxide