title: Enzyme-free signal amplification in the DNAzyme sensor via target-catalyzed hairpin assembly.
abstract: A simple, highly sensitive and enzyme-free DNAzyme sensor based on target-catalyzed hairpin assembly is developed, which permits detection of 0.1 pM target DNA. Furthermore, this DNAzyme sensor is capable of detecting target DNA in real samples because of its high selectivity.
authors.affiliation: The Key Lab of Analysis and Detection Technology for Food Safety of the MOE, College of Chemistry and Chemical Engineering, Fuzhou University, Fuzhou 350108, P. R. China.
authors.forename: Ai-Xian
authors.initials: AX
authors.lastname: Zheng
authors.forename: Juan
authors.initials: J
authors.lastname: Li
authors.forename: Jin-Ru
authors.initials: JR
authors.lastname: Wang
authors.forename: Xiao-Rong
authors.initials: XR
authors.lastname: Song
authors.forename: Guo-Nan
authors.initials: GN
authors.lastname: Chen
authors.forename: Huang-Hao
authors.initials: HH
authors.lastname: Yang
mesh_terms: D055162:Biocatalysis; D015374:Biosensing Techniques / Q000379:methods*; D004247:DNA / Q000032:analysis* / Q000737:chemistry; D021881:DNA, Catalytic; D009690:Nucleic Acid Conformation; D012680:Sensitivity and Specificity
chemical_list: D021881:DNA, Catalytic; D004247:DNA