title: In vivo physiological saline-infused hepatic vessel imaging using a two-crystal-interferometer-based phase-contrast X-ray technique.
abstract: Using a two-crystal-interferometer-based phase-contrast X-ray imaging system, the portal vein, capillary vessel area and hepatic vein of live rats were revealed sequentially by injecting physiological saline via the portal vein. Vessels greater than 0.06 mm in diameter were clearly shown with low levels of X-rays (552 µGy). This suggests that in vivo vessel imaging of small animals can be performed as conventional angiography without the side effects of the presently used iodine contrast agents.
authors.affiliation: Allied Health Sciences and Graduate School of Medical Science, Kitasato University, 1-15-1 Kitasato, Minami-ku, Sagamihara, Kanagawa 252-0373, Japan.
authors.forename: Tohoru
authors.initials: T
authors.lastname: Takeda
authors.forename: Akio
authors.initials: A
authors.lastname: Yoneyama
authors.forename: Jin
authors.initials: J
authors.lastname: Wu
authors.forename: Atsushi
authors.initials: A
authors.lastname: Momose
authors.forename: Kazuyuki
authors.initials: K
authors.lastname: Hyodo
mesh_terms: D000792:Angiography / Q000379:methods*; D000818:Animals; D002196:Capillaries / Q000000981:diagnostic imaging; D003287:Contrast Media; D007368:Interferometry; D008099:Liver / Q000098:blood supply* / Q000000981:diagnostic imaging; D008102:Liver Circulation; D010477:Perfusion / Q000379:methods; D011169:Portal Vein / Q000000981:diagnostic imaging*; D011856:Radiographic Image Enhancement / Q000379:methods; D051381:Rats; D017208:Rats, Wistar; D012965:Sodium Chloride; D014965:X-Rays
chemical_list: D003287:Contrast Media; D012965:Sodium Chloride