title: [Synthesis of A-secomethylenamino- and substituted amidoximotriterpenoids].
abstract: Development of the functionalization of triterpenoids to A-secoamidoximes, A-secomethylenamines and branched 3-(3-aminopropylamino)-3-(3-aminopropoxy)amidoximes is illustrated by the betulonic acid ketoxime. An effective way to get of the derivatives of 20,29-dihydrolupanes using diborane is suggested. The antiviral and anti-tuberculosis activity data of some compounds are presented.
authors.forename: O B
authors.initials: OB
authors.lastname: Kazakova
authors.forename: G V
authors.initials: GV
authors.lastname: Giniiatullina
authors.forename: G A
authors.initials: GA
authors.lastname: Tolstikov
mesh_terms: D000995:Antitubercular Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D000998:Antiviral Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D006801:Humans; D009980:Influenza A virus / Q000187:drug effects; D015394:Molecular Structure; D009169:Mycobacterium tuberculosis / Q000187:drug effects; D009828:Oleanolic Acid / Q000031:analogs & derivatives* / Q000737:chemistry; D010091:Oximes / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D012229:Rhinovirus / Q000187:drug effects; D045473:Severe acute respiratory syndrome-related coronavirus / Q000187:drug effects; D013329:Structure-Activity Relationship; D014315:Triterpenes / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D000094062:Betulinic Acid
chemical_list: D000995:Antitubercular Agents; D000998:Antiviral Agents; D009828:Oleanolic Acid; D010091:Oximes; D014315:Triterpenes; C118308:betulonic acid; D000094062:Betulinic Acid