title: Health-related quality-of-life after traumatic brain injury: a 2-year follow-up study in Wuhan, China.
abstract: OBJECTIVE
  To assess health-related quality-of-life (HRQoL) 2 years after traumatic brain injury (TBI) among a group of Chinese.
  
  
  METHODS
  A total of 358 adult patients with moderate-to-severe TBI based on Glasgow Coma Scale score were recruited in a large trauma centre in Wuhan, China during May 2005 to April 2008. They were followed up for 2 years and the Medical Outcome Short Form 36 was used to measure HRQoL.
  
  
  RESULTS
  After a 2-year follow-up, there were 312 (87.2%) survivors. All domains of HRQoL had the lowest scores at discharge, greatly improved over the first 6 months and showed continued improvement. Patients with TBI still had significantly lower scores in every domain than the reference group 2 years after discharge. Female patients had lower MCS scores than the males (OR = 1.8, 95% CI: 1.1-2.9). Patients older than 30 had lower scores in PCS (OR = 1.7, 95% CI: 1.1-2.6). Patients with severe TBI had lower scores in both PCS (OR = 1.9, 95% CI: 1.2-3.1) and MCS (OR = 1.6, 95% CI: 1.0-2.6) compared with those with moderate TBI.
  
  
  CONCLUSIONS
  HRQoL of a group of Chinese patients with TBI improved during 2 years after discharge. Age, sex and severity of TBI were significantly associated with physical or mental HRQoL after discharge.
authors.affiliation: Department of Neurosurgery, Wuhan Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, PR China. huxb7276@163.com
authors.forename: Xue-Bin
authors.initials: XB
authors.lastname: Hu
authors.forename: Zhe
authors.initials: Z
authors.lastname: Feng
authors.forename: Yu-Cong
authors.initials: YC
authors.lastname: Fan
authors.forename: Zhi-Yong
authors.initials: ZY
authors.lastname: Xiong
authors.forename: Qi-Wei
authors.initials: QW
authors.lastname: Huang
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D001930:Brain Injuries / Q000453:epidemiology* / Q000534:rehabilitation; D002681:China / Q000453:epidemiology; D005260:Female; D005500:Follow-Up Studies; D015600:Glasgow Coma Scale; D006304:Health Status; D006801:Humans; D008297:Male; D008875:Middle Aged; D011788:Quality of Life; D020127:Recovery of Function; D012720:Severity of Illness Index; D012737:Sex Factors; D011795:Surveys and Questionnaires; D016896:Treatment Outcome; D055815:Young Adult