title: False-positive lesions mimicking breast cancer on FDG PET and PET/CT.
abstract: OBJECTIVE
  Incidental (18)F-FDG-avid breast lesions are commonly encountered in patients with cancer who undergo staging PET/CT. This pictorial essay discusses breast lesions that show increased FDG activity, mimicking breast cancer, with biopsy-confirmed benign diagnosis.
  
  
  CONCLUSIONS
  Acute and chronic inflammation, physiologic lactation, and benign breast masses, including silicone granuloma, fat necrosis, fibroadenoma, and postsurgical changes, may show increased FDG uptake on PET/CT. These conditions can often be differentiated from malignancy by correlative imaging, including mammography, sonography, or MRI.
authors.affiliation: Department of Diagnostic Radiology, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Blvd, Unit 1350, Houston, TX 77030, USA.
authors.forename: Margaret
authors.initials: M
authors.lastname: Adejolu
authors.forename: Lei
authors.initials: L
authors.lastname: Huo
authors.forename: Eric
authors.initials: E
authors.lastname: Rohren
authors.forename: Lumarie
authors.initials: L
authors.lastname: Santiago
authors.forename: Wei T
authors.initials: WT
authors.lastname: Yang
mesh_terms: D001706:Biopsy; D001941:Breast Diseases / Q000000981:diagnostic imaging*; D001943:Breast Neoplasms / Q000000981:diagnostic imaging; D003937:Diagnosis, Differential; D005189:False Positive Reactions; D005260:Female; D019788:Fluorodeoxyglucose F18; D006099:Granuloma / Q000000981:diagnostic imaging; D006801:Humans; D033162:Incidental Findings; D007774:Lactation; D008413:Mastitis / Q000000981:diagnostic imaging; D064847:Multimodal Imaging; D009336:Necrosis / Q000000981:diagnostic imaging; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18