title: [Clinical characteristics and surgical outcomes of intracranial aneurysm: a retrospective study of 3322 cases].
abstract: OBJECTIVE
  To preliminarily explore the clinical characteristics and surgical outcomes of intracranial aneurysm.
  
  
  METHODS
  The data of 3322 cases of intracranial aneurysm from January 1955 to July 2009 were collected at our hospital for analysis. The clinical characteristics and surgical outcomes of patients with intracranial aneurysm were assessed. The surgical patients were divided into 2 groups by the date of admission: group A and group B. Such clinical characteristics as age, gender and Hunt-Hess grade at admission and first presentations were analyzed. The surgical outcomes were assessed by comparing the surgical complications between two groups.
  
  
  RESULTS
  Intracranial aneurysms were commonly diagnosed between 38 and 54 years old. Hemorrhage (84.89%), mass effect (8.13%) and non-hemorrhagic headache (5.18%) were the three initial common presentations and the male-to-female ratio was 0.875:1. There was no significant statistical difference in age distribution and gender ratio between two groups. According to the Hunt-Hess grade, the percentage of grades II, III and IV was lower in group B while the percentage of grades 0 and I higher than group A. No significant difference was found in the overall incidence of major post-operative complications between two groups (P > 0.05).
  
  
  CONCLUSIONS
  The major presentations of intracranial aneurysm are hemorrhage, mass effect and non-hemorrhagic headache. And the Hunt-Hess grades I and II patients account for a majority of aneurysms. Three most common locations of aneurysm are ICA-PCoA (internal carotid artery-posterior communicating artery), ACoA (anterior communicating artery) and MCA (middle cerebral artery). Giant aneurysm should be treated in the light of concrete conditions by choosing such a surgical approach as bypass.
authors.affiliation: Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing 100050, China.
authors.forename: Shu
authors.initials: S
authors.lastname: Li
authors.forename: Shuo
authors.initials: S
authors.lastname: Wang
authors.forename: Yuan-li
authors.initials: YL
authors.lastname: Zhao
authors.forename: Dong
authors.initials: D
authors.lastname: Zhang
authors.forename: Ji-zong
authors.initials: JZ
authors.lastname: Zhao
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D002532:Intracranial Aneurysm / Q000175:diagnosis* / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D016896:Treatment Outcome