title: Calcium hydroxylapatite nodule resolution after fractional carbon dioxide laser therapy.
abstract: BACKGROUND
  Injection of calcium hydroxylapatite filler may result in nodule formation owing to superficial placement of the filler. Calcium hydroxylapatite nodules are difficult to reverse. Previously reported therapeutic options are limited and include intralesional triamcinolone, massage, needling, and excision, each with inconsistent results or potential for scarring.
  
  
  METHODS
  We have observed complete resolution of calcium hydroxylapatite nodules after a single treatment with fractional carbon dioxide laser.
  
  
  CONCLUSIONS
  A single session of fractional carbon dioxide laser treatment may resolve selected cases of calcium hydroxylapatite nodules. The mechanism of action may involve conversion of the product into tricalcium phosphates which dissolve readily. This novel therapeutic technique may enhance treatment options for a difficult clinical problem.
authors.affiliation: Laser & Skin Surgery Center of New York, New York, NY 10016, USA. kreddy@laserskinsurgery.com
authors.forename: Kavitha K
authors.initials: KK
authors.lastname: Reddy
authors.forename: Jeremy A
authors.initials: JA
authors.lastname: Brauer
authors.forename: Robert
authors.initials: R
authors.lastname: Anolik
authors.forename: Leonard
authors.initials: L
authors.lastname: Bernstein
authors.forename: Lori A
authors.initials: LA
authors.lastname: Brightman
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Hale
authors.forename: Julie
authors.initials: J
authors.lastname: Karen
authors.forename: Elliot
authors.initials: E
authors.lastname: Weiss
authors.forename: Roy G
authors.initials: RG
authors.lastname: Geronemus
mesh_terms: D000328:Adult; D001672:Biocompatible Materials / Q000008:administration & dosage / Q000009:adverse effects; D019882:Blepharoplasty / Q000009:adverse effects* / Q000379:methods; D017886:Durapatite / Q000008:administration & dosage / Q000009:adverse effects*; D005143:Eyelids; D005260:Female; D005500:Follow-Up Studies; D015745:Granuloma, Foreign-Body / Q000175:diagnosis / Q000209:etiology / Q000601:surgery*; D006801:Humans; D056965:Injections, Intraocular; D053685:Laser Therapy / Q000379:methods*; D054020:Lasers, Gas / Q000627:therapeutic use*
chemical_list: D001672:Biocompatible Materials; D017886:Durapatite