title: [Conservative therapy of chronic sinusitis].
abstract: The chronic rhinosinusitis is defined as chronic inflammation of the nose and nasal sinuses, with or without nasal polyps. Patients suffering from chronic rhinosinusitis report about nasal obstruction and secretion, olfactory impairment, head and facial pain. These symptoms cause also considerable impact on quality of life. Therefore, an adequate rhinological diagnostics as well as therapies are essential. This paper reviews the pharmacologic and non-pharmacologic therapy of chronic rhinosinusitis. First choice of therapy should be topical glucocorticoids. The application of glucocorticoids causes anti-inflammatory and certain curative effects. Hypertonic salt solutions improve nasal symptoms. Long-term therapy with oral macrolides might improve median to severe symptoms of chronic rhinosinusitis without nasal polyps. An additional therapy with antihistamines is possible in patients with an allergy. Adaptive desensitization in patients suffering from analgesic-intolerance associating among other with nasal polyps is currently the single causal therapy. Therefore, frequency of endonasal revision surgery is reduced after desensitization.
authors.affiliation: Elblandkliniken Radebeul, HNO-Abteilung, Heinrich-Zille-Str 13, 01445 Radebeul. michael.reiss@elblandkliniken.de
authors.forename: Michael
authors.initials: M
authors.lastname: Reiss
authors.forename: Gilfe
authors.initials: G
authors.lastname: Reiss
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D002908:Chronic Disease; D000529:Complementary Therapies; D003888:Desensitization, Immunologic; D005938:Glucocorticoids / Q000627:therapeutic use; D006633:Histamine Antagonists / Q000627:therapeutic use; D006801:Humans; D006967:Hypersensitivity / Q000150:complications / Q000188:drug therapy; D020024:Leukotriene Antagonists / Q000627:therapeutic use; D015508:Nasal Obstruction / Q000188:drug therapy; D010256:Paranasal Sinuses; D012852:Sinusitis / Q000175:diagnosis / Q000188:drug therapy* / Q000453:epidemiology / Q000209:etiology
chemical_list: D000900:Anti-Bacterial Agents; D000893:Anti-Inflammatory Agents; D005938:Glucocorticoids; D006633:Histamine Antagonists; D020024:Leukotriene Antagonists