title: Catalytic generation of arynes and trapping by nucleophilic addition and iodination.
abstract: A fair exchange: in the title reaction, alkynyllithium serves as an initiator for benzyne generation through an iodine-lithium exchange. When performed in the presence of stoichiometric amounts of a nucleophile, the generated benzyne undergoes attack by lithio nucleophiles to generate aryllithium, which is then iodinated by iodoalkyne to give the iodoarenes 1.
authors.affiliation: Department of Chemistry, School of Science and Technology, Kwansei Gakuin University, Gakuen, Sanda, Hyogo, Japan. thamura@kwansei.ac.jp
authors.forename: Toshiyuki
authors.initials: T
authors.lastname: Hamura
authors.forename: Yu
authors.initials: Y
authors.lastname: Chuda
authors.forename: Yuya
authors.initials: Y
authors.lastname: Nakatsuji
authors.forename: Keisuke
authors.initials: K
authors.lastname: Suzuki