title: [A case of pancreatic cancer with celiac trunk and common hepatic artery invasion successfully resected after gemcitabine+S-1therapy].
abstract: We present a case of a 59-year-old female who was admitted to our hospital for upper abdominal pain. She was diagnosed with pancreatic body carcinoma by computed tomography and magnetic resonance imaging. We started gemcitabine+S-1 chemotherapy because the tumor had invaded the celiac trunk, common hepatic artery, superior mesenteric vein, and splenic vein. We reduced the S-1 to 100mg/body after the third course of gemcitabine(1, 000mg/m2 on days 1 and 8, every 21 days)+S-1(120mg/body on days 1-14, every 21 days)because of side effects. The tumor became smaller, and the celiac trunk and common hepatic artery were released. Thus, we conducted a distal pancreatectomy with a D2 lymph node dissection.
authors.affiliation: Dept. of Thoracic and Visceral Organ Surgery, Gunma University Graduate School of Medicine, Japan.
authors.forename: Ryuji
authors.initials: R
authors.lastname: Katoh
authors.forename: Izumi
authors.initials: I
authors.lastname: Takeyoshi
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Sunose
authors.forename: Daisuke
authors.initials: D
authors.lastname: Yoshinari
authors.forename: Osamu
authors.initials: O
authors.lastname: Totsuka
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Toya
authors.forename: Hiroomi
authors.initials: H
authors.lastname: Ogawa
authors.forename: Keitaro
authors.initials: K
authors.lastname: Hirai
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002445:Celiac Artery / Q000473:pathology*; D003841:Deoxycytidine / Q000008:administration & dosage / Q000031:analogs & derivatives; D004338:Drug Combinations; D005260:Female; D006499:Hepatic Artery / Q000473:pathology*; D006801:Humans; D008099:Liver / Q000098:blood supply*; D008875:Middle Aged; D020360:Neoadjuvant Therapy; D009361:Neoplasm Invasiveness; D010094:Oxonic Acid / Q000008:administration & dosage; D010190:Pancreatic Neoplasms / Q000098:blood supply / Q000188:drug therapy* / Q000601:surgery; D005641:Tegafur / Q000008:administration & dosage; D014057:Tomography, X-Ray Computed; D000093542:Gemcitabine
chemical_list: D004338:Drug Combinations; D003841:Deoxycytidine; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid; D000093542:Gemcitabine