title: miRviewer: a multispecies microRNA homologous viewer.
abstract: BACKGROUND
  MicroRNAs (miRNAs) are short non-coding RNAs that regulate gene expression via binding to the 3' ends of mRNAs. MiRNAs have been associated with many cellular events ascertaining their central role in gene regulation. In order to better understand miRNAs of interest it is of utmost importance to learn about the genomic conservation of these genes.
  
  
  RESULTS
  The miRviewer web-server, presented here, encompasses all known miRNAs of currently fully annotated animal genomes in a visual 'birds-eye' view representation. miRviewer provides a graphical outlook of the current miRNA world together with sequence alignments and secondary structures of each miRNA. As a test case we experimentally examined the expression of several miRNAs in various animals.
  
  
  CONCLUSIONS
  miRviewer completes the homologous miRNA space with hundreds of unreported miRNAs and is available at: http://people.csail.mit.edu/akiezun/miRviewer.
authors.affiliation: Department of Cell and Developmental Biology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv 69978, Israel. nshomron@post.tau.ac.il.
authors.forename: Adam
authors.initials: A
authors.lastname: Kiezun
authors.forename: Shay
authors.initials: S
authors.lastname: Artzi
authors.forename: Shira
authors.initials: S
authors.lastname: Modai
authors.forename: Naama
authors.initials: N
authors.lastname: Volk
authors.forename: Ofer
authors.initials: O
authors.lastname: Isakov
authors.forename: Noam
authors.initials: N
authors.lastname: Shomron