title: Effect of endurance and strength exercise on release of brain natriuretic peptide.
abstract: OBJECTIVE
  The aim of this study was to investigate the effects of 8-week endurance and resistance exercise training on release of brain natriuretic peptide.
  
  
  METHODS
  Study population was categorized into 4 groups: Group-1 (n = 6) consisted of sedentary individuals who volunteered to complete 8-weeks of endurance exercise; Group-2 (n=6) consisted of sedentary individuals who volunteered to complete 8-weaks of resistance exercise. Three blood samples [for Terminal pro BNP (NT-Pro-BNP)] were taken before, immediately after exercise and after 8 weeks of exercise training.
  
  
  RESULTS
  NT-Pro BNP was significantly increased immediately after endurance exercise [from 37.9 ± 1.4 pg/ml to 52.1 ±1.5 pg/ml; P = 0.002] and was decreased to 23.2 ± 9.3 pg/ml after 8 weeks of endurance exercise [P = 0.013]. On the other hand, NT-Pro BNP showed no significant changes immediately after resistance exercise [from 26.6 ± 4.9 pg/ml to 24.1 ±4.5 pg/ml; P = 0.553]. In contrast, NT-Pro BNP was significantly increased to 39.5 ±1.6 pg/ml after 8 weeks of resistance exercise [P = 0.012].
  
  
  CONCLUSIONS
  Endurance exercise training reduces circulating NT-Pro BNP concentration, which is likely a marker of reduced ventricular wall tension and improved myocardial function. In contrast, strength exercise induces significant increase in NT-Pro BNP, which could be partially attributed to myocardial damage.
authors.affiliation: Fars Sciences and Research Branch, Azad University, Shiraz, Iran.
authors.forename: Somayeh
authors.initials: S
authors.lastname: Bordbar
authors.forename: Mohammad Ali Babaee
authors.initials: MA
authors.lastname: Bigi
authors.forename: Amir
authors.initials: A
authors.lastname: Aslani
authors.forename: Eskandar
authors.initials: E
authors.lastname: Rahimi
authors.forename: Nader
authors.initials: N
authors.lastname: Ahmadi