title: Ambient Schmittel cyclization promoted by chemoselective triazole-gold catalyst.
abstract: The Schmittel cyclization was achieved at room temperature through triazole-gold (TA-Au) catalyzed propargyl vinyl ether rearrangement. Other tested [L-Au](+) catalysts gave complex reaction mixtures under identical conditions with no desired products observed. Importantly, because of the employment of mild conditions, sterically hindered groups (such as t-Bu) on allene termini were no longer required, which allowed successful synthesis of previously challenging substrates.
authors.affiliation: C. Eugene Bennett Department of Chemistry, West Virginia University, Morgantown, West Virginia 26506, USA.
authors.forename: Qiaoyi
authors.initials: Q
authors.lastname: Wang
authors.forename: Siddhita
authors.initials: S
authors.lastname: Aparaj
authors.forename: Novruz G
authors.initials: NG
authors.lastname: Akhmedov
authors.forename: Jeffrey L
authors.initials: JL
authors.lastname: Petersen
authors.forename: Xiaodong
authors.initials: X
authors.lastname: Shi
mesh_terms: D002384:Catalysis; D003500:Cyclization; D006046:Gold / Q000737:chemistry*; D008958:Models, Molecular; D015394:Molecular Structure; D014230:Triazoles / Q000737:chemistry*
chemical_list: D014230:Triazoles; D006046:Gold