title: Pharmacovigilance of herbal medicine.
abstract: Pharmacovigilance is essential for developing reliable information on the safety of herbal medicines as used in Europe and the US. The existing systems were developed for synthetic medicines and require some modification to address the specific differences of medicinal herbs. Traditional medicine from many different cultures is used in Europe and the US which adds to the complexities and difficulties of even basic questions such as herb naming systems and chemical variability. Allied to this also is the perception that a 'natural' or herbal product must be safe simply because it is not synthetic which means that the safety element of monitoring for such medicines can be overlooked because of the tag associated with such products. Cooperation between orthodox physicians and traditional practitioners is needed to bring together the full case details. Independent scientific assistance on toxicological investigation, botanical verification can be invaluable for full evaluation of any case report. Systematic pharmacovigilance is essential to build up reliable information on the safety of herbal medicines for the development of appropriate guidelines for safe effective use.
authors.affiliation: Chinese Medicine Advisory Service, Medical Toxicology Information Services, Guy's & St Thomas NHS Foundation Trust, Guy's Hospital, London SE1 9RT, UK.
authors.forename: Debbie
authors.initials: D
authors.lastname: Shaw
authors.forename: Ladds
authors.initials: L
authors.lastname: Graeme
authors.forename: Duez
authors.initials: D
authors.lastname: Pierre
authors.forename: Williamson
authors.initials: W
authors.lastname: Elizabeth
authors.forename: Chan
authors.initials: C
authors.lastname: Kelvin
mesh_terms: D003257:Consumer Product Safety; D003299:Cooperative Behavior; D064420:Drug-Related Side Effects and Adverse Reactions; D005060:Europe; D029001:Herbal Medicine; D006801:Humans; D008519:Medicine, Traditional; D060735:Pharmacovigilance; D008517:Phytotherapy / Q000009:adverse effects*; D028321:Plant Preparations / Q000009:adverse effects*; D010946:Plants, Medicinal / Q000009:adverse effects*; D011786:Quality Control; D014481:United States
chemical_list: D028321:Plant Preparations