title: The growing clinical importance of secondary tricuspid regurgitation.
abstract: Functional or secondary tricuspid regurgitation (STR) is the most frequent etiology of tricuspid valve pathology in Western countries. Surgical tricuspid repair has been avoided for years, because of the misconception that tricuspid regurgitation should disappear once the primary left-sided problem is treated; this results in a large number of untreated patients with STR. Over the past few years, many investigators have reported evidence in favor of a more aggressive surgical approach to STR. Consequently, interest has been growing in the physiopathology and treatment of STR. The purpose of this review is to explore the anatomical basis, pathophysiology, therapeutic approach, and future perspectives with regard to the management of STR.
authors.affiliation: Cardiothoracic Surgery, San Raffaele Scientific Institute, Milan, Italy. taramasso.maurizio@hsr.it
authors.forename: Maurizio
authors.initials: M
authors.lastname: Taramasso
authors.forename: Hugo
authors.initials: H
authors.lastname: Vanermen
authors.forename: Francesco
authors.initials: F
authors.lastname: Maisano
authors.forename: Andrea
authors.initials: A
authors.lastname: Guidotti
authors.forename: Giovanni
authors.initials: G
authors.lastname: La Canna
authors.forename: Ottavio
authors.initials: O
authors.lastname: Alfieri
mesh_terms: D003937:Diagnosis, Differential; D003952:Diagnostic Imaging / Q000379:methods*; D019918:Heart Valve Prosthesis Implantation / Q000379:methods*; D006801:Humans; D014262:Tricuspid Valve Insufficiency / Q000175:diagnosis / Q000209:etiology / Q000601:surgery