title: [Comprehensive analysis of relevant factors on colorectal cancer-related anemia].
abstract: OBJECTIVE
  To analyze the risk factors of colorectal cancer-related anemia.
  
  
  METHODS
  The clinical data of 319 patients with colorectal cancer were retrospectively analyzed for the possible risk factors of tumor-related anemia including tumor location, clinical stage, clinical symptoms, pathology, gender, and age.
  
  
  RESULTS
  Of these 319 cases, 141 (44.20%) had anemia. The incidence of anemia was 62.20% among patients with right hemicolon cancers (including caecum cancer), and was 23.82% among patients with rectal cancer and 36.23% among those with transverse descending or sigmoid colon cancer. Cardia insufficiency, melena, tumor location, T staging, hypoproteinemia were also found to be related with anemia. Anemia and hypoproteinemia were the risk factors for perioperative blood transfusion (odds ratio = 3.004, odds ratio = 8.356, respectively).
  
  
  CONCLUSIONS
  The colorectal cancer-related anemia is not associated with the clinical stage of the tumor, while cardiac insufficiency, melena, tumor location, tumor stage, and hypoproteinemia constitute the possible risk factors. Anemia and hypoproteinemia are the risk factors of perioperative blood transfusion.
authors.affiliation: Department of General Surgery, PUMC Hospital, CAMS and PUMC, Beijing 100730, China.
authors.forename: Jun-Na
authors.initials: JN
authors.lastname: Ge
authors.forename: Jian-Chun
authors.initials: JC
authors.lastname: Yu
authors.forename: Wei-Ming
authors.initials: WM
authors.lastname: Kang
authors.forename: Zhi-Qiang
authors.initials: ZQ
authors.lastname: Ma
authors.forename: Ying-Chao
authors.initials: YC
authors.lastname: Gu
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000740:Anemia / Q000209:etiology*; D015179:Colorectal Neoplasms / Q000150:complications*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012307:Risk Factors