title: [The genetics of Gilles de la Tourette syndrome].
abstract: Knowledge about the aetiology of Gilles de la Tourette syndrome (GTS) is very limited. GTS has a complex mode of inheritance in which both genetic and environmental factors are believed to be involved in disease development. Different approaches to identify GTS associated genes have led to the discovery of several candidate genes. However, none of these has been shown to be major causative genes associated with the development of GTS. Future use of large clinical cohorts and new technologies will hopefully result in the identification of genes associated with GTS.
authors.affiliation: Center for Anvendt Human Molekylærgenetik, Kennedy Centret, Gl. Landevej 7, 2600 Glostrup, Denmark.
authors.forename: Birgitte
authors.initials: B
authors.lastname: Bertelsen
authors.forename: Linea
authors.initials: L
authors.lastname: Melchior
authors.forename: Nanette Mol
authors.initials: NM
authors.lastname: Debes
authors.forename: Liselotte
authors.initials: L
authors.lastname: Skov
authors.forename: Karen
authors.initials: K
authors.lastname: Brøndum-Nielsen
authors.forename: Zeynep
authors.initials: Z
authors.lastname: Tümer
mesh_terms: D002869:Chromosome Aberrations; D020732:Cytogenetic Analysis; D008040:Genetic Linkage; D005820:Genetic Testing; D055106:Genome-Wide Association Study; D006801:Humans; D005879:Tourette Syndrome / Q000209:etiology / Q000235:genetics*; D018433:Twin Studies as Topic