title: Inhibition of histone H3K9 methyltransferases by gliotoxin and related epipolythiodioxopiperazines.
authors.affiliation: Chemical Genetics Laboratory, RIKEN Advanced Science Institute, Wako, Japan.
authors.forename: Masanari
authors.initials: M
authors.lastname: Takahashi
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Takemoto
authors.forename: Tadahiro
authors.initials: T
authors.lastname: Shimazu
authors.forename: Hisashi
authors.initials: H
authors.lastname: Kawasaki
authors.forename: Makoto
authors.initials: M
authors.lastname: Tachibana
authors.forename: Yoichi
authors.initials: Y
authors.lastname: Shinkai
authors.forename: Motoki
authors.initials: M
authors.lastname: Takagi
authors.forename: Kazuo
authors.initials: K
authors.lastname: Shin-ya
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Igarashi
authors.forename: Akihiro
authors.initials: A
authors.lastname: Ito
authors.forename: Minoru
authors.initials: M
authors.lastname: Yoshida
mesh_terms: D001381:Azepines / Q000737:chemistry / Q000494:pharmacology; D003460:Crystallization; D004220:Disulfides / Q000494:pharmacology; D015195:Drug Design; D004791:Enzyme Inhibitors / Q000494:pharmacology*; D005912:Gliotoxin / Q000737:chemistry / Q000494:pharmacology*; D000076983:Histone Methyltransferases; D011495:Histone-Lysine N-Methyltransferase / Q000037:antagonists & inhibitors*; D026121:Indole Alkaloids / Q000494:pharmacology; D008745:Methylation / Q000187:drug effects; D010879:Piperazines / Q000737:chemistry / Q000494:pharmacology*; D011799:Quinazolines / Q000737:chemistry / Q000494:pharmacology
chemical_list: D001381:Azepines; C518299:BIX 01294; D004220:Disulfides; D004791:Enzyme Inhibitors; D026121:Indole Alkaloids; D010879:Piperazines; D011799:Quinazolines; C001598:chetomin; C002511:chaetocin; D005912:Gliotoxin; D000076983:Histone Methyltransferases; D011495:Histone-Lysine N-Methyltransferase; C540279:11,11'-dideoxyverticillin A