title: Endometriosis-associated ovarian cancer. Presentation of a case report and review of the literature.
abstract: Endometriosis is a frequent benign disease presenting in more than 10% of women in reproductive age. Although its course is usually benign, it has characteristics of malignant disease, such as progressive course, implantation at distant sites, creation of a microenvironment that renders its course independent and mobilization of the immune system in order to prevent its destruction. Endometriosis-associated ovarian cancer (EAOC) is encountered in 0.3-1.0% of cases of endometriosis. We present in the current article a case of EAOC, reviewing the literature for epidemiological data and data of genetics, and other possible associated factors that lead to the pathogenesis of the disease.
authors.affiliation: Department of Gynecology, Athens General Hospital "Laiko", Athens, Greece. pergialiotis@hotmail.com
authors.forename: V
authors.initials: V
authors.lastname: Pergialiotis
authors.forename: A
authors.initials: A
authors.lastname: Lagkadas
authors.forename: O
authors.initials: O
authors.lastname: Polychronis
authors.forename: S
authors.initials: S
authors.lastname: Natsis
authors.forename: D
authors.initials: D
authors.lastname: Karakalpakis
authors.forename: K
authors.initials: K
authors.lastname: Giannakopoulos
mesh_terms: D000328:Adult; D004715:Endometriosis / Q000150:complications* / Q000601:surgery; D005260:Female; D006801:Humans; D019656:Loss of Heterozygosity; D010049:Ovarian Diseases / Q000150:complications*; D010051:Ovarian Neoplasms / Q000209:etiology* / Q000401:mortality / Q000601:surgery