title: Management strategies for acute proximal deep vein thrombosis: a Delphi consensus.
abstract: OBJECTIVE
  Deep vein thrombosis (DVT) is a leading cause of cardiovascular disease. We tested the hypothesis that there is a consensus regarding the treatment of acute DVT among clinicians experienced in DVT management.
  
  
  METHODS
  A Delphi consensus approach was used to gather expert opinion regarding attitudes towards the treatment of acute proximal DVT and management of specific cases. Strength of preference for various treatment strategies across a number of case scenarios was quantified. Univariate and multivariate analyses were performed to quantify the influence of various factors on treatment modality selected.
  
  
  RESULTS
  Respondents strongly agreed that DVT was a significant health problem and that further research was a priority. A multidisciplinary team approach with access to various treatment strategies was encouraged. Pregnancy and recent surgery independently predicted preference for medical treatment, whereas proximal DVT and May-Thurner syndrome were associated with interventional strategies.
  
  
  CONCLUSIONS
  Acute proximal DVT is a significant health problem for which a variety of treatments are available. This study demonstrates that no consensus exists as to the optimum strategy for certain patient groups. Trends in opinion based on local experience and case-series exist, but the results of ongoing randomized trials will ultimately inform best practice.
authors.affiliation: Department of Outcomes Research, St George's Vascular Institute, London SW17 0QT, UK.
authors.forename: B O
authors.initials: BO
authors.lastname: Patterson
authors.forename: A
authors.initials: A
authors.lastname: Karthikesalingam
authors.forename: R
authors.initials: R
authors.lastname: Morgan
authors.forename: B J
authors.initials: BJ
authors.lastname: Hunt
authors.forename: M M
authors.initials: MM
authors.lastname: Thompson
authors.forename: P J E
authors.initials: PJ
authors.lastname: Holt
mesh_terms: D000208:Acute Disease; D032921:Consensus; D003697:Delphi Technique; D005260:Female; D006801:Humans; D008297:Male; D011183:Postoperative Complications / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy; D012307:Risk Factors; D015912:Thrombolytic Therapy; D020246:Venous Thrombosis / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology / Q000628:therapy*