title: Risk factors for nasal carriage of methicillin-resistant Staphylococcus aureus among patients with end-stage renal disease in Taiwan.
abstract: OBJECTIVE
  Patients with end-stage renal disease (ESRD) are at particular risk for methicillin-resistant Staphylococcus aureus (MRSA) infections, especially via nasal colonization of MRSA. Surveillance cultures are recommended to identify patients colonized by MRSA.
  
  
  METHODS
  Clinical data and screening cultures of S. aureus from the anterior nares of 541 patients on long-term dialysis in the hospitals were performed in March 2007. The follow-up survey was conducted 1 year later.
  
  
  RESULTS
  A total of 32 (5.9%) of the 541 patients were positive nasal cultures for MRSA, while 89 (16.5%) were positive for methicillin-susceptible S. aureus (MSSA). In a multivariate analysis, risk factors for ESRD patients with MRSA colonization included congestive heart failure, nursing home admission, and nasogastric tube feeding in the last 3 months. Follow-up of the 32 MRSA colonized patients showed that one (3.1%) died due to MSSA and three (9.3%) died due from MRSA infection.
  
  
  CONCLUSIONS
  We found that patients with ESRD and MRSA nasal colonization were associated with a history of congestive heart failure, nursing home admission, and nasogastric tube feeding in the last 3 months.
authors.affiliation: Department of Internal Medicine, Cardinal Tien Hospital, Fu-Jen Catholic University, Taipei, Taiwan.
authors.forename: Cheng-Yi
authors.initials: CY
authors.lastname: Wang
authors.forename: Vin-Cent
authors.initials: VC
authors.lastname: Wu
authors.forename: Wei-Jie
authors.initials: WJ
authors.lastname: Wang
authors.forename: Yu-Feng
authors.initials: YF
authors.lastname: Lin
authors.forename: Yen-Hung
authors.initials: YH
authors.lastname: Lin
authors.forename: Yung-Ming
authors.initials: YM
authors.lastname: Chen
authors.forename: Chi-Ting
authors.initials: CT
authors.lastname: Su
authors.forename: Jen-Yu
authors.initials: JY
authors.lastname: Wang
authors.forename: Kwan-Dun
authors.initials: KD
authors.lastname: Wu
authors.forename: Po-Ren
authors.initials: PR
authors.lastname: Hsueh
mesh_terms: D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002353:Carrier State / Q000453:epidemiology; D016022:Case-Control Studies; D017714:Community-Acquired Infections / Q000175:diagnosis*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D007676:Kidney Failure, Chronic / Q000150:complications*; D008297:Male; D055624:Methicillin-Resistant Staphylococcus aureus / Q000187:drug effects / Q000302:isolation & purification*; D008875:Middle Aged; D015999:Multivariate Analysis; D009296:Nasal Cavity / Q000382:microbiology*; D011379:Prognosis; D012307:Risk Factors; D013203:Staphylococcal Infections / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology*; D013624:Taiwan / Q000453:epidemiology; D055815:Young Adult
chemical_list: D000900:Anti-Bacterial Agents