title: Proton pump inhibitors: concerns over prolonged use.
abstract: Proton pump inhibitors are amongst the most over prescribed drugs in clinical practice. These drugs were purported to have excellent safety profile. However in the recent past, certain adverse events have been reported which are of clinical significance. Although the linkage of adverse events with proton pump inhibitors appears to be biologically plausible, the clinical evidence for the linkage requires further confirmation. The current review discusses the available evidence regarding these adverse events.
authors.affiliation: Department of Gastroenterology, All India Institute of Medical Sciences, New Delhi - 110029, India.
authors.forename: V Pratap
authors.initials: VP
authors.lastname: Mouli
authors.forename: Vineet
authors.initials: V
authors.lastname: Ahuja
mesh_terms: D002986:Clinical Trials as Topic; D004347:Drug Interactions; D019317:Evidence-Based Medicine; D006801:Humans; D007408:Intestinal Absorption / Q000187:drug effects; D054328:Proton Pump Inhibitors / Q000008:administration & dosage / Q000009:adverse effects*; D012307:Risk Factors
chemical_list: D054328:Proton Pump Inhibitors