title: Alteration in mean platelet volume and platicrit values in patients with cancer that developed thrombosis.
abstract: Mean platelet volume (MPV) is an indicator of thrombocyte volume and tendency to thrombosis can be mentioned in case of MPV elevation. Cancers are one of the important groups of thrombotic diseases. In the present study, MPV value was scrutinized in patients with cancer that developed thrombosis. Totally 43 patients followed in Kayseri Training and Research Hospital, in who thromboembolus has been developed, were prospectively recruited in the study. Thrombocyte, MPV, and platicrit (PCT) values were recorded at the time of cancer diagnosis and thrombosis development. Frequency analysis, crosstabs, and paired samples t test were used. Analyses showed that MPV values at the time of thrombosis development were significantly low as compared to those at the time of cancer diagnosis (P = .041). Thrombocyte count and PCT values were also low but not significant. The result of the present study is likely to show that thrombocytes have ignorable effect on thrombosis development in patients with cancer.
authors.affiliation: Department of Medical Oncology, Kayseri Training and Research Hospital, Kayseri, Turkey. doktorhasanmutlu@gmail.com
authors.forename: Hasan
authors.initials: H
authors.lastname: Mutlu
authors.forename: Tarik A
authors.initials: TA
authors.lastname: Artis
authors.forename: Abdülsamet
authors.initials: A
authors.lastname: Erden
authors.forename: Zeki
authors.initials: Z
authors.lastname: Akca
mesh_terms: D000328:Adult; D000368:Aged; D001792:Blood Platelets / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D063847:Mean Platelet Volume; D008875:Middle Aged; D009369:Neoplasms / Q000097:blood / Q000150:complications*; D011446:Prospective Studies; D013927:Thrombosis / Q000097:blood / Q000453:epidemiology / Q000209:etiology*