title: Friedel-Crafts-type allylation of nitrogen-containing aromatic compounds with allylic alcohols catalyzed by a [Mo3S4Pd(η3-allyl)] cluster.
abstract: With the direct use of allylic alcohols as allylating agents, the Friedel-Crafts-type allylic alkylation of nitrogen-containing aromatic compounds catalyzed by a [Mo(3)S(4)Pd(η(3)-allyl)] cluster is achieved. With a 3 mol % catalyst loading in acetonitrile at reflux or 60 °C, a variety of N,N-dialkylanilines and indoles reacted smoothly with allylic alcohols to afford the Friedel-Crafts-type allylation products in good to excellent yields with high levels of regioselectivity.
authors.affiliation: State Key Laboratory of Fine Chemicals, School of Pharmaceutical Science and Technology, Faculty of Chemical, Environmental and Biological Science and Technology, Dalian University of Technology, Dalian 116024, P. R. China.
authors.forename: Yinsong
authors.initials: Y
authors.lastname: Tao
authors.forename: Baomin
authors.initials: B
authors.lastname: Wang
authors.forename: Jinfeng
authors.initials: J
authors.lastname: Zhao
authors.forename: Yuming
authors.initials: Y
authors.lastname: Song
authors.forename: Lihong
authors.initials: L
authors.lastname: Qu
authors.forename: Jingping
authors.initials: J
authors.lastname: Qu
mesh_terms: D000478:Alkylation; D002384:Catalysis; D007211:Indoles / Q000737:chemistry*; D015394:Molecular Structure; D008982:Molybdenum / Q000737:chemistry*; D009584:Nitrogen / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*; D020005:Propanols; D013237:Stereoisomerism
chemical_list: D007211:Indoles; D020005:Propanols; C006463:allyl alcohol; D010165:Palladium; D008982:Molybdenum; D009584:Nitrogen