title: Assisted reproductive technology in Europe, 2007: results generated from European registers by ESHRE.
abstract: BACKGROUND
  This 11th European IVF-monitoring report presents the results of assisted reproductive technology (ART) treatments initiated in Europe during 2007.
  
  
  METHODS
  From 33 countries, 1029 clinics reported 493 184 treatment cycles: IVF (120 761), ICSI (256 642), frozen embryo replacement (91 145), egg donation (15 731), preimplantation genetic diagnosis/preimplantation genetic screening (4638), in vitro maturation (660) and frozen oocytes replacements (3607). Overall, this represents a 7.6% increase since 2006, mostly related to an increase in all registers. IUI using husband/partner's (IUI-H) and donor (IUI-D) semen was reported from 23 countries: 142 609 IUI-H (+6.2%) and 26 088 IUI-D (+7.2%).
  
  
  RESULTS
  In 18 countries where all clinics reported, 376 971 ART cycles were performed in a population of 425.6 million (886 cycles per million). The clinical pregnancy rates per aspiration and per transfer were 29.1 and 32.8% for IVF, and 28.6 and 33.0% for ICSI. Delivery rate after IUI-H was 10.2% in women aged < 40 years. In IVF/ICSI cycles, 1, 2, 3 and ≥4 embryos were transferred in 21.4, 53.4, 22.7 and 2.5% of cycles, with no decline in the number of embryos per transfer since 2006. The proportion of multiple deliveries (22.3: 21.3% twin and 1.0% triplet), did not decrease compared with 2006 (20.8%) and 2005 (21.8%). In women < 40 years undergoing IUI-H, twin deliveries occurred in 11.7% and triplets in 0.5%.
  
  
  CONCLUSIONS
  In comparison with previous years, the reported number of ART cycles in Europe increased in 2007; pregnancy rates increased marginally, but the earlier decline in the number of embryos transferred and multiple births did not continue.
authors.affiliation: ESHRE Central Office, Meerstraat 60, B-1852 Grimbergen, Belgium. jacques.demouzon@inserm.fr
authors.forename: J
authors.initials: J
authors.lastname: de Mouzon
authors.forename: V
authors.initials: V
authors.lastname: Goossens
authors.forename: S
authors.initials: S
authors.lastname: Bhattacharya
authors.forename: J A
authors.initials: JA
authors.lastname: Castilla
authors.forename: A P
authors.initials: AP
authors.lastname: Ferraretti
authors.forename: V
authors.initials: V
authors.lastname: Korsak
authors.forename: M
authors.initials: M
authors.lastname: Kupka
authors.forename: K G
authors.initials: KG
authors.lastname: Nygren
authors.forename: A Nyboe
authors.initials: AN
authors.lastname: Andersen
mesh_terms: D000293:Adolescent; D000328:Adult; D004624:Embryo Transfer / Q000639:trends; D005060:Europe / Q000453:epidemiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011247:Pregnancy; D011248:Pregnancy Complications / Q000453:epidemiology; D011256:Pregnancy Outcome / Q000453:epidemiology; D018873:Pregnancy Rate; D019836:Preimplantation Diagnosis / Q000639:trends; D012042:Registries; D027724:Reproductive Techniques, Assisted / Q000639:trends*; D012955:Societies, Medical