title: Quantitative elastography provided by surface acoustic waves measured by phase-sensitive optical coherence tomography.
abstract: We report on a quantitative elastography technique achieved by combining phase-sensitive optical coherence tomography (PhS-OCT) with the surface acoustic wave (SAW) method. Different from traditional optical coherence elastography, the elastography is achieved by impulse-stimulated SAW, rather than by shear waves. PhS-OCT serves not only as a detector to measure SAW signals but also as a means to provide a cross-sectional image of the sample. The experimental results indicate that the combination of PhS-OCT with SAW is feasible to provide quantitative elastography of heterogeneous tissue samples.
authors.affiliation: Department of Bioengineering, University of Washington, Seattle, Washington 98195, USA.
authors.forename: Chunhui
authors.initials: C
authors.lastname: Li
authors.forename: Guangying
authors.initials: G
authors.lastname: Guan
authors.forename: Xi
authors.initials: X
authors.lastname: Cheng
authors.forename: Zhihong
authors.initials: Z
authors.lastname: Huang
authors.forename: Ruikang K
authors.initials: RK
authors.lastname: Wang
mesh_terms: D000362:Agar / Q000737:chemistry; D000465:Algorithms; D054459:Elasticity Imaging Techniques / Q000379:methods*; D006801:Humans; D021621:Imaging, Three-Dimensional / Q000379:methods*; D012867:Skin / Q000166:cytology / Q000473:pathology; D013016:Sound; D041623:Tomography, Optical Coherence / Q000379:methods*
chemical_list: D000362:Agar