title: Some lessons about models from Michaelis and Menten.
abstract: Michaelis and Menten's classic 1913 paper on enzyme kinetics is used to draw some lessons about the relationship between mathematical models and biological reality.
authors.affiliation: Department of Systems Biology, Harvard Medical School, Boston, MA 02115, USA. jeremy@hms.harvard.edu
authors.forename: Jeremy
authors.initials: J
authors.lastname: Gunawardena
mesh_terms: D004798:Enzymes / Q000737:chemistry* / Q000266:history; D049673:History, 20th Century; D007700:Kinetics; D008956:Models, Chemical; D013379:Substrate Specificity; D049490:Systems Biology / Q000193:education* / Q000266:history
chemical_list: D004798:Enzymes