title: [The clinical study of epithelioid angiosarcoma in deep soft tissue].
abstract: OBJECTIVE
  To analyze the histopathology of, surgery for, and prognosis (survival rate, local recurrence rate, metastases rate, function) of epithelioid angiosarcoma (EA).
  
  
  METHODS
  Seven patients diagnosed as EA were received treatment in our department from May 2001 to May 2011. According Enneking staging, 3 patients were classified as IIA, 3 for IIB, and 1 for III. Wide excision was performed in 3 patients and amputation in 4 patients. Seven patients were followed up from 3 to 20 months.
  
  
  RESULTS
  One patient had local recurrence 3 months after wide excision. Five patients had metastases at 4 to 20 months postoperatively. The cumulative survival rate at 0.5, 1 and 2 years postoperatively were 67%, 22% and 0. The function of 3 patients after limb salvage operation was good in 2 cases and poor in 1 case. The tumor site, surgical staging, and safe margin were crucial factors affecting survival rate.
  
  
  CONCLUSIONS
  The prognosis of EA in deep soft tissue was poor. Customized, multimodality treatment and safe margin in operation may increase the survival rate as well as decrease recurrence and metastasis.
authors.affiliation: Department of Orthopaedic Oncology, Xijing Hospital, the Fourth Military Medical University, Xi'an 710032, China.
authors.forename: Hong-bin
authors.initials: HB
authors.lastname: Fan
authors.forename: Zheng
authors.initials: Z
authors.lastname: Guo
authors.forename: Zhi-gang
authors.initials: ZG
authors.lastname: Wu
authors.forename: Xiang-dong
authors.initials: XD
authors.lastname: Li
authors.forename: Jing
authors.initials: J
authors.lastname: Li
authors.forename: Zhen
authors.initials: Z
authors.lastname: Wang
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D006394:Hemangiosarcoma / Q000175:diagnosis / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D009364:Neoplasm Recurrence, Local; D011379:Prognosis; D012189:Retrospective Studies; D012983:Soft Tissue Neoplasms / Q000175:diagnosis / Q000601:surgery*; D015996:Survival Rate; D016896:Treatment Outcome