title: 7q-and loss of a polymorphism for the met oncogene in a patient with myelofibrosis.
abstract: The met oncogene is the normal counterpart of a chemically-induced transforming gene. The chromosomal localization of met is 7q21-31. In a patient with myelofibrosis and an interstitial deletion on 7q, we demonstrate that a Taq I polymorphism for the met oncogene is lost in the neoplastic cells, thus indicating that the deletion occuring in the long arm of chromosome 7 involves the met locus.
authors.affiliation: Dipartimento di Scienze Biomediche e Oncologia Umana, University of Turin, Via Genova 3, 10126, Torino, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Rege-Cambrin
authors.forename: A
authors.initials: A
authors.lastname: Guerrasio
authors.forename: A
authors.initials: A
authors.lastname: Serra
authors.forename: A
authors.initials: A
authors.lastname: Alfarano
authors.forename: A
authors.initials: A
authors.lastname: Stacchini
authors.forename: P
authors.initials: P
authors.lastname: Lusso
authors.forename: G
authors.initials: G
authors.lastname: Benetton
authors.forename: M
authors.initials: M
authors.lastname: Aglietta
authors.forename: M
authors.initials: M
authors.lastname: Bonetto
authors.forename: G
authors.initials: G
authors.lastname: Saglio