title: Synthesis of [1,2,3]triazolo[1,5-a]quinoxalin-4(5H)-ones through copper-catalyzed tandem reactions of N-(2-haloaryl)propiolamides with sodium azide.
abstract: A simple and efficient approach for the synthesis of [1,2,3]triazolo[1,5-a]quinoxalin-4(5H)-ones is described. The methodology is based on a tandem reaction of 1-(2-haloaryl)propiolamides with sodium azide through a [3 + 2] azide-alkyne cycloaddition and intramolecular Ullmann-type C-N coupling process.
authors.affiliation: Key Laboratory of Regenerative Biology and Institute of Chemical Biology, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, No. 190 Kaiyuan Avenue, Guangzhou Science Park, Guangzhou, 510530, China.
authors.forename: Jiajie
authors.initials: J
authors.lastname: Yan
authors.forename: Fengtao
authors.initials: F
authors.lastname: Zhou
authors.forename: Dongguang
authors.initials: D
authors.lastname: Qin
authors.forename: Tong
authors.initials: T
authors.lastname: Cai
authors.forename: Ke
authors.initials: K
authors.lastname: Ding
authors.forename: Qian
authors.initials: Q
authors.lastname: Cai
mesh_terms: D000577:Amides / Q000737:chemistry*; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D003500:Cyclization; D015394:Molecular Structure; D011810:Quinoxalines / Q000737:chemistry*; D019810:Sodium Azide / Q000737:chemistry*; D014230:Triazoles / Q000138:chemical synthesis*
chemical_list: D000577:Amides; D011810:Quinoxalines; D014230:Triazoles; D003300:Copper; D019810:Sodium Azide