title: Risk factors for surgical complications after central pancreatectomy.
abstract: OBJECTIVE
  Central pancreatectomy is a pancreas-sparing alternative to standard pancreatic resections in selected cases. Although associated with high morbidity, the risk factors for surgical complications of this procedure are not yet defined.
  
  
  METHODS
  The clinicopathological and perioperative data of 24 patients who underwent central pancreatectomies (2002-2010) were correlated with surgical complications.
  
  
  RESULTS
  The overall morbidity rate was 54% (pancreatic fistula, 40%). In a univariate analysis, age over 40 years, body mass index ≥30kg/m2, smoking and American Society of Anesthesiologists III scores were significantly correlated with increased morbidity. In a multivariate analysis, a significant correlation with the development of complications was found for body mass index ≥30kg/m2 and age over 40 years.
  
  
  CONCLUSIONS
  Certain patient-related factors (older age, obesity and smoking) appear to have a negative impact on early postoperative outcome after central pancreatectomy. For patients with these factors, an alternative distal pancreatectomy should be considered. Central pancreatectomy should be tailored not only to the pathology but also to the patient profile.
authors.affiliation: Fundeni Clinical Institute, Bucharest, Romania. traian.dumitrascu@srchirurgie.ro
authors.forename: Traian
authors.initials: T
authors.lastname: Dumitrascu
authors.forename: Sorin T
authors.initials: ST
authors.lastname: Barbu
authors.forename: Raluca
authors.initials: R
authors.lastname: Purnichescu-Purtan
authors.forename: Mihnea
authors.initials: M
authors.lastname: Ionescu
authors.forename: Irinel
authors.initials: I
authors.lastname: Popescu
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D015992:Body Mass Index; D016009:Chi-Square Distribution; D015897:Comorbidity; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D009765:Obesity / Q000150:complications; D010180:Pancreatectomy / Q000009:adverse effects*; D010185:Pancreatic Fistula / Q000209:etiology*; D010190:Pancreatic Neoplasms / Q000601:surgery*; D011183:Postoperative Complications / Q000209:etiology*; D012189:Retrospective Studies; D012307:Risk Factors; D012907:Smoking / Q000009:adverse effects; D013997:Time Factors; D016896:Treatment Outcome; D055815:Young Adult