title: Cortisone associated diverticular perforation.
abstract: Patients on glucocorticosteroid therapy are at increased risk of gastrointestinal perforation. The associated morbidity and mortality of perforations in this group is increased, compared with normal groups. This difference is due to the delay between onset of clinical symptoms and treatment. In the presence of steroids, gastrointestinal perforation is more difficult to diagnose clinically because signs and symptoms of perforation are masked by the anti-inflammatory effect of the steroids.
authors.affiliation: Department of Radiology, UZ Brussel, Vrije Universiteit Brussel (VUB), Brussels, Belgium. Lode.Goethals@vub.ac.be
authors.forename: L
authors.initials: L
authors.lastname: Goethals
authors.forename: K
authors.initials: K
authors.lastname: Nieboer
authors.forename: K
authors.initials: K
authors.lastname: De Smet
authors.forename: E
authors.initials: E
authors.lastname: De Geeter
authors.forename: N Hosseinpour
authors.initials: NH
authors.lastname: Tabrizi
authors.forename: E
authors.initials: E
authors.lastname: Van Eetvelde
authors.forename: J
authors.initials: J
authors.lastname: de Mey
mesh_terms: D000893:Anti-Inflammatory Agents / Q000009:adverse effects*; D003348:Cortisone / Q000009:adverse effects*; D003937:Diagnosis, Differential; D004240:Diverticulum / Q000139:chemically induced* / Q000000981:diagnostic imaging / Q000601:surgery; D006801:Humans; D007416:Intestinal Perforation / Q000139:chemically induced* / Q000000981:diagnostic imaging / Q000601:surgery; D008297:Male; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000188:drug therapy; D014057:Tomography, X-Ray Computed
chemical_list: D000893:Anti-Inflammatory Agents; D003348:Cortisone