title: Resistant Kawasaki disease treated with anti-CD20.
abstract: We report the case of a 6-year-old boy who had Kawasaki disease resistant to intravenous immunoglobulin and systemic steroids. Because of an uncontrolled disease course, with significant lesions of the coronary arteries, anti-CD20 treatment was used. Rapid clinical, biological, and cardiac improvement was observed. The patient tolerated the treatment well.
authors.affiliation: Unité de Médecine Infantile, CHU Timone Enfants, Marseille, France.
authors.forename: Emilie
authors.initials: E
authors.lastname: Sauvaget
authors.forename: Béatrice
authors.initials: B
authors.lastname: Bonello
authors.forename: Marion
authors.initials: M
authors.lastname: David
authors.forename: Brigitte
authors.initials: B
authors.lastname: Chabrol
authors.forename: Jean-Christophe
authors.initials: JC
authors.lastname: Dubus
authors.forename: Emmanuelle
authors.initials: E
authors.lastname: Bosdure
mesh_terms: D058846:Antibodies, Monoclonal, Murine-Derived / Q000008:administration & dosage*; D001774:Blood Chemical Analysis; D002648:Child; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D004351:Drug Resistance; D015150:Echocardiography, Doppler; D005500:Follow-Up Studies; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D007155:Immunologic Factors / Q000008:administration & dosage*; D008297:Male; D009080:Mucocutaneous Lymph Node Syndrome / Q000175:diagnosis / Q000188:drug therapy*; D018570:Risk Assessment; D000069283:Rituximab; D012720:Severity of Illness Index; D016896:Treatment Outcome
chemical_list: D058846:Antibodies, Monoclonal, Murine-Derived; D016756:Immunoglobulins, Intravenous; D007155:Immunologic Factors; D000069283:Rituximab