title: Genesis of ultrasonic microbubbles: a quick historical overview.
abstract: Microbubbles were the subject of numerous experiments and theoretical analysis over the past 100 years. Linked with the discovery and evolution of ultrasound, they were considered to be excellent echoenhancers. From the theories on acoustic waves in antiquity and the discovery of ultrasound, to the genesis of microbubbles around 1968, in our paper we trace the magnificent story of these "magical" bubbles.
authors.affiliation: History of Medicine Department, Medical School, University of Athens, Greece. mariannakaramanou@yahoo.com
authors.forename: Marianna
authors.initials: M
authors.lastname: Karamanou
authors.forename: Theodore G
authors.initials: TG
authors.lastname: Papaioannou
authors.forename: Christodoulos
authors.initials: C
authors.lastname: Stefanadis
authors.forename: George
authors.initials: G
authors.lastname: Androutsos
mesh_terms: D000162:Acoustics; D003287:Contrast Media / Q000737:chemistry / Q000266:history*; D049672:History, 19th Century; D049673:History, 20th Century; D006801:Humans; D045423:Microbubbles / Q000266:history*; D014463:Ultrasonography / Q000266:history* / Q000379:methods
chemical_list: D003287:Contrast Media