title: Titanium-containing bioactive phosphate glasses.
abstract: The use of biomaterials has revolutionized the biomedical field and has received substantial attention in the last two decades. Among the various types of biomaterials, phosphate glasses have generated great interest on account of their remarkable bioactivity and favourable physical properties for various biomedical applications relating to both hard and soft tissue regeneration. This review paper focuses mainly on the development of titanium-containing phosphate-based glasses and presents an overview of the structural and physical properties. The effect of titanium incorporation on the glassy network is to introduce favourable properties. The biocompatibility of these glasses is described along with recent developments in processing methodologies, and the potential of Ti-containing phosphate-based glasses as a bone substitute material is explored.
authors.affiliation: Division of Biomaterials and Tissue Engineering, University College London Eastman Dental Institute, 256 Gray's Inn Road, London WC1X 8LD, UK.
authors.forename: A
authors.initials: A
authors.lastname: Kiani
authors.forename: N J
authors.initials: NJ
authors.lastname: Lakhkar
authors.forename: V
authors.initials: V
authors.lastname: Salih
authors.forename: M E
authors.initials: ME
authors.lastname: Smith
authors.forename: J V
authors.initials: JV
authors.lastname: Hanna
authors.forename: R J
authors.initials: RJ
authors.lastname: Newport
authors.forename: D M
authors.initials: DM
authors.lastname: Pickup
authors.forename: J C
authors.initials: JC
authors.lastname: Knowles
mesh_terms: D000818:Animals; D002516:Ceramics / Q000737:chemistry*; D020099:Coated Materials, Biocompatible / Q000737:chemistry*; D005898:Glass / Q000737:chemistry*; D006801:Humans; D008422:Materials Testing; D010710:Phosphates / Q000737:chemistry*; D019736:Prostheses and Implants; D013499:Surface Properties; D014025:Titanium / Q000737:chemistry*
chemical_list: D020099:Coated Materials, Biocompatible; D010710:Phosphates; D014025:Titanium