title: The significance of clinical features in the prognosis of acute renal infarction: single center experience.
abstract: OBJECTIVE
  Acute renal infarct (ARI) is a common renovascular disease caused by the abrupt interruption of renal blood flow. Since the presenting symptoms are often non-specific, a major concern in ARI has been prompt diagnosis, and its long-term outcome has never been studied.
  
  
  METHODS
  From January 2000 through to December 2009, adult patients with ARI were enrolled in this study. We retrospectively reviewed their clinical data, and followed them up until July 2011. Renal outcome and all-cause mortality were measured.
  
  
  RESULTS
  A total of 67 patients were finally enrolled in this study. Their mean age was 56.1 ± 16.4 years, and 52.2% of them were male. Over 76% of patients were identified to have more than one comorbidity and concurrent thromboembolic events occurred in 16.4% of the patients. Although, acute kidney injury (AKI) was present in 40.7% of the patients, long-term renal outcome was relatively good. In all cases, AKI was resolved within a month, and renal loss was found in only one patient. In-hospital mortality was 8.9% and during the median follow-up period of 40.6 months, long-term mortality was 19.7%. Independent risk factors for mortality were age, atrial fibrillation, myocardial infarction and hematuria [hazard ratio (HR) 1.051, 95% confidence interval (CI) 1.008-1.096; HR 3.322, 95% CI 1.119-9.860; HR 9.315, 95% CI 1.555-55.796 and HR 7.745, 95% CI 1.606-37.353, respectively].
  
  
  CONCLUSIONS
  Our study suggested that in-hospital and long-term outcomes of ARI were closely related to the comorbidities or underlying disease of ARI, rather than the disease itself.
authors.affiliation: Division of Nephrology, Department of Internal Medicine, Pusan National University Hospital, Gudeok-ro 179, Seo-gu, Busan 602-739, Republic of Korea.
authors.forename: Harin
authors.initials: H
authors.lastname: Rhee
authors.forename: Sang Heon
authors.initials: SH
authors.lastname: Song
authors.forename: Dong
authors.initials: D
authors.lastname: Won Lee
authors.forename: Soo Bong
authors.initials: SB
authors.lastname: Lee
authors.forename: Ihm Soo
authors.initials: IS
authors.lastname: Kwak
authors.forename: Eun Young
authors.initials: EY
authors.lastname: Seong
mesh_terms: D058186:Acute Kidney Injury / Q000453:epidemiology; D000328:Adult; D000368:Aged; D015897:Comorbidity; D005260:Female; D017052:Hospital Mortality; D006801:Humans; D007238:Infarction / Q000175:diagnosis* / Q000453:epidemiology / Q000473:pathology*; D007668:Kidney / Q000098:blood supply*; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012189:Retrospective Studies