title: Inability to perform posterior segment monitoring by scanning laser ophthalmoscopy or optical coherence tomography with some occlusive intraocular lenses in clinical use.
abstract: OBJECTIVE
  To evaluate whether occlusive intraocular lenses (IOLs) produced by several manufacturers for clinical use equivalently transmit near-infrared (IR) light for scanning laser ophthalmoscopy (SLO) or optical coherence tomography (OCT) imaging.
  
  
  METHODS
  Nuffield Laboratory of Ophthalmology, Oxford University, United Kingdom.
  
  
  METHODS
  Evaluation of diagnostic test or technology.
  
  
  METHODS
  The study evaluated 6 black IOLs of 2 designs: 3 poly(methyl methacrylate) (PMMA) and 3 iris-claw anterior chamber IOLs. Each IOL was placed between a broad-spectrum white light source and a spectroradiometer to generate transmission spectra. Transmission in the near-IR range was examined using an 850 nm light-emitting diode. Scanning laser ophthalmoscopy or OCT imaging using Spectralis spectral-domain SLO or OCT was attempted through occlusive IOLs in a model eye.
  
  
  RESULTS
  Artisan iris-claw and MS 612 PMMA occlusive IOLs totally occluded all wavelengths of light, including in the near IR range in which SLO and OCT imaging systems operate. It was not possible to capture SLO or OCT images through the iris-claw and PMMA occlusive IOLs in a model eye.
  
  
  CONCLUSIONS
  Results suggest the property of near-IR transmission that permits SLO or OCT imaging through occlusive IOLs is restricted to the Morcher range of occlusive IOLs. Patients with non-near IR transmitting IOLs will not be able to receive detailed posterior segment monitoring with SLO or OCT. This finding may have a significant impact on preoperative occlusive IOL selection and the management of current patients with occlusive IOLs.
  
  
  BACKGROUND
  No author has a financial or proprietary interest in any material or method mentioned.
authors.affiliation: Nuffield Laboratory of Ophthalmology, Oxford University, Oxford, United Kingdom.
authors.forename: Imran H
authors.initials: IH
authors.lastname: Yusuf
authors.forename: Stuart N
authors.initials: SN
authors.lastname: Peirson
authors.forename: Chetan K
authors.initials: CK
authors.lastname: Patel
mesh_terms: D006801:Humans; D007834:Lasers; D019654:Lens Implantation, Intraocular; D007910:Lenses, Intraocular; D008962:Models, Theoretical; D008991:Monitoring, Physiologic; D009887:Ophthalmoscopy; D055095:Optics and Photonics; D019904:Polymethyl Methacrylate; D057972:Posterior Eye Segment / Q000473:pathology*; D011474:Prosthesis Design; D012164:Retinal Diseases / Q000175:diagnosis; D019265:Spectroscopy, Near-Infrared; D041623:Tomography, Optical Coherence; D014603:Uveal Diseases / Q000175:diagnosis
chemical_list: D019904:Polymethyl Methacrylate