title: Can lifestyle interventions do more than reduce diabetes risk? Treating depression in adults with type 2 diabetes with exercise and cognitive behavioral therapy.
abstract: The epidemic of metabolic syndrome, prediabetes, and type 2 diabetes is global in scope and comprehensive in its impact on individuals, health care systems, and societies. One in four patients with diabetes will experience depression in their lifetime. Comorbid depression is associated with poorer outcomes, greater functional disability, and early mortality. Prior studies have demonstrated beneficial effects of exercise as an efficacious form of treatment for depression in the general population. Few studies have evaluated this strategy in patients with prediabetes or type 2 diabetes. Program ACTIVE (Appalachians Coming Together to Increase Vital Exercise) was designed to treat depression among adults with type 2 diabetes by pairing aerobic activity with individual cognitive behavioral therapy. This combination treatment approach has been shown to be feasible to implement in a rural environment and promising in terms of depression, diabetes, and cardiovascular outcomes. Data from this study suggest that exercise can be used to achieve multiple benefits for adults with type 2 diabetes. Future work to compare this approach to singular treatment strategies for adults at risk for type 2 diabetes is needed.
authors.affiliation: Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA. mdegroot@iupui.edu
authors.forename: Mary
authors.initials: M
authors.lastname: de Groot
authors.forename: Todd
authors.initials: T
authors.lastname: Doyle
authors.forename: Michael
authors.initials: M
authors.lastname: Kushnick
authors.forename: Jay
authors.initials: J
authors.lastname: Shubrook
authors.forename: Jennifer
authors.initials: J
authors.lastname: Merrill
authors.forename: Erin
authors.initials: E
authors.lastname: Rabideau
authors.forename: Frank
authors.initials: F
authors.lastname: Schwartz
mesh_terms: D015928:Cognitive Behavioral Therapy / Q000379:methods; D003863:Depression / Q000517:prevention & control / Q000523:psychology / Q000628:therapy*; D003924:Diabetes Mellitus, Type 2 / Q000517:prevention & control / Q000523:psychology / Q000628:therapy*; D015444:Exercise; D005260:Female; D006293:Health Promotion; D006801:Humans; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000517:prevention & control / Q000523:psychology / Q000628:therapy*; D009820:Ohio / Q000453:epidemiology; D017060:Patient Satisfaction; D010865:Pilot Projects; D011236:Prediabetic State / Q000517:prevention & control / Q000523:psychology / Q000628:therapy*; D012307:Risk Factors; D011795:Surveys and Questionnaires; D014903:West Virginia / Q000453:epidemiology