title: Novel association of multiple gastrointestinal anomalies in a single patient: can Sonic Hedgehog explain it?
abstract: The occurrence of four gastrointestinal (GIT) anomalies in a single patient is extremely rare. Only one report of four GIT anomalies in a child has been published in the English literature. The current report presents a child with four anomalies and discusses the molecular mechanisms which control the development of the gastrointestinal tract.
authors.affiliation: Department of Pediatric Surgery, Advanced Pediatric Center and Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India. drkirtirathod@gmail.com
authors.forename: Kirtikumar J
authors.initials: KJ
authors.lastname: Rathod
authors.forename: Dhananjay
authors.initials: D
authors.lastname: Vaze
authors.forename: Kannan L
authors.initials: KL
authors.lastname: Narasimhan
mesh_terms: D000015:Abnormalities, Multiple / Q000175:diagnosis / Q000235:genetics*; D000071056:Anorectal Malformations; D001006:Anus, Imperforate / Q000235:genetics; D004380:Duodenal Obstruction / Q000235:genetics; D004933:Esophageal Atresia / Q000235:genetics; D017809:Fatal Outcome; D041981:Gastrointestinal Tract / Q000002:abnormalities*; D053823:Hedgehog Proteins / Q000235:genetics*; D006801:Humans; D007231:Infant, Newborn; D007409:Intestinal Atresia; D008297:Male; D015398:Signal Transduction; D014138:Tracheoesophageal Fistula / Q000235:genetics
chemical_list: D053823:Hedgehog Proteins; C509239:SHH protein, human