title: Aphasia severity and salivary cortisol over time.
abstract: The current study explored the complicated interplay between aphasia and the stress biomarker, cortisol, in left-hemisphere (LH) and right-hemisphere (RH) stroke patients. Nineteen LH patients and 12 RH patients began the study between one to six months post stroke and were followed for three months. During this time, language skills were assessed monthly while afternoon salivary cortisol samples were collected biweekly. The LH and RH groups showed improvements in language test scores over the course of three months; however, only naming skills in the RH group appeared to be associated with afternoon salivary cortisol levels. Furthermore, contradicting previous reports regarding laterality and cortisol regulation in humans, the current study found that both LH patients and RH patients exhibited similar afternoon salivary cortisol levels across all time points.
authors.affiliation: Communication Disorders Program and Neuroscience Institute, Georgia State University, Atlanta, GA, USA. jlaures@gsu.edu
authors.forename: Jacqueline S
authors.initials: JS
authors.lastname: Laures-Gore
mesh_terms: D000328:Adult; D000368:Aged; D001037:Aphasia / Q000209:etiology / Q000378:metabolism*; D005260:Female; D007839:Functional Laterality / Q000502:physiology*; D006801:Humans; D006854:Hydrocortisone / Q000378:metabolism*; D007807:Language Tests; D008297:Male; D008875:Middle Aged; D012463:Saliva / Q000378:metabolism*; D020521:Stroke / Q000150:complications; D013997:Time Factors
chemical_list: D006854:Hydrocortisone