title: Optical coherence tomographic assessment of macular thickness and morphological patterns in diabetic macular edema: prognosis after modified grid photocoagulation.
abstract: BACKGROUND
  The topographic mapping is useful for monitoring patients for the development of macular edema and following the resolution of edema after laser treatment.
  
  
  OBJECTIVE
  To evaluate the usefulness of optical coherence tomography (OCT) for mapping of macula after laser therapy in clinically significant macular edema (CSME).
  
  
  METHODS
  A prospective study was carried out enrolling 60 eyes of 35 patients with the diagnosis of CSME. OCT was performed at first visit and every successive follow up visit. The retinal thickness was measured automatically using OCT retinal mapping software.
  
  
  METHODS
  Correlation between vision status and central macular thickness (CMT) was done using the Spearman's correlation test. The analysis of variance (ANOVA) and independent t-test were used for comparison of groups.
  
  
  RESULTS
  The OCT revealed sponge like thickening pattern (ST) in 67.4 % followed by cystoid macular edema (CME) in 19.6 %. Best corrected visual acuity (BCVA) improved in 89.1 % after 6 months of treatment. There was high correlation between vision status and CMT (P =less than 0.001). The mean values of baseline CMT were 301.68 (+/-134.738), 434.83 (+/-180.758), 518.67 (+/- 275.184), 327 (+/-108.393) and 334.85 (+/- 158.91) microns for the OCT patterns of ST, CME, sub-foveal detachment (SFD), vitreo-macular interface abnormality (VMIA) and average CMT respectively (p=0.042).
  
  
  CONCLUSIONS
  OCT is a useful tool for evaluating CSME. It can show the various morphological variants of CSME while the BCVA and CMT are fairly different.
authors.affiliation: Geta Eye Hospital, Dhangadhi, Nepal. drarjuns@hotmail.com
authors.forename: A
authors.initials: A
authors.lastname: Shrestha
authors.forename: N
authors.initials: N
authors.lastname: Maharjan
authors.forename: A
authors.initials: A
authors.lastname: Shrestha
authors.forename: R
authors.initials: R
authors.lastname: Thapa
authors.forename: G
authors.initials: G
authors.lastname: Poudyal
mesh_terms: D003930:Diabetic Retinopathy / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D005500:Follow-Up Studies; D006801:Humans; D017075:Laser Coagulation / Q000379:methods*; D008266:Macula Lutea / Q000473:pathology* / Q000601:surgery; D008269:Macular Edema / Q000175:diagnosis* / Q000209:etiology / Q000601:surgery; D011379:Prognosis; D011446:Prospective Studies; D013997:Time Factors; D041623:Tomography, Optical Coherence / Q000379:methods*