title: [Investigation of the role of Zn2+ and zinc-containing proteins in the pathogenesis of bone inflammmation (the case of periodontitis)].
abstract: The levels of Ag, Al, Bi, Co, Cr, Fe, Mo, Si in osseous tissue of periodontium of domestic cats decreased in case of periodontitis in comparision with those of a healthy animals. At the same time the level of Zn increased dramatically. The level of tagged [14C] glycine in protein of bones of periodontium increased twofold and [35S] methionine 1,54 times which is explained by the fact of predominance of I type collagen in which one third of amino acids is represented by glycine while sulfur-containing amino acids are virtually absent. The latter are contained in non-collagenous proteins of bones of periodontium contributing for its metabolism. The difference in tagged aminoacids inclusion in bones of periodontium is mainly provoked by redistribution of the collagen and non-collagenous proteins.
authors.forename: Iu A
authors.initials: IuA
authors.lastname: Petrovich
authors.forename: T D
authors.initials: TD
authors.lastname: Ramazanov
authors.forename: S M
authors.initials: SM
authors.lastname: Kichenko
authors.forename: V K
authors.initials: VK
authors.lastname: Lebedev
mesh_terms: D000818:Animals; D002415:Cats; D008667:Metalloproteins / Q000378:metabolism*; D010000:Osteitis / Q000378:metabolism* / Q000473:pathology; D010518:Periodontitis / Q000378:metabolism* / Q000473:pathology; D015032:Zinc / Q000378:metabolism*
chemical_list: D008667:Metalloproteins; D015032:Zinc