title: Voice and emotion processing in the human neonatal brain.
abstract: Although the voice-sensitive neural system emerges very early in development, it has yet to be demonstrated whether the neonatal brain is sensitive to voice perception. We measured the EEG mismatch response (MMR) elicited by emotionally spoken syllables "dada" along with correspondingly synthesized nonvocal sounds, whose fundamental frequency contours were matched, in 98 full-term newborns aged 1-5 days. In Experiment 1, happy syllables relative to nonvocal sounds elicited an MMR lateralized to the right hemisphere. In Experiment 2, fearful syllables elicited stronger amplitudes than happy or neutral syllables, and this response had no sex differences. In Experiment 3, angry versus happy syllables elicited an MMR, although their corresponding nonvocal sounds did not. Here, we show that affective discrimination is selectively driven by voice processing per se rather than low-level acoustical features and that the cerebral specialization for human voice and emotion processing emerges over the right hemisphere during the first days of life.
authors.affiliation: Institute of Neuroscience and Brain Research Center, National Yang-Ming University, Taipei, Taiwan. ywcheng2@ym.edu.tw
authors.forename: Yawei
authors.initials: Y
authors.lastname: Cheng
authors.forename: Shin-Yi
authors.initials: SY
authors.lastname: Lee
authors.forename: Hsin-Yu
authors.initials: HY
authors.lastname: Chen
authors.forename: Ping-Yao
authors.initials: PY
authors.lastname: Wang
authors.forename: Jean
authors.initials: J
authors.lastname: Decety
mesh_terms: D000161:Acoustic Stimulation / Q000379:methods*; D000328:Adult; D001921:Brain / Q000254:growth & development*; D004193:Discrimination Learning / Q000502:physiology; D004644:Emotions / Q000502:physiology*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D013067:Speech Perception / Q000502:physiology*; D014831:Voice