title: Enantioselective gold-catalyzed synthesis of polycyclic indolines.
abstract: The synthesis of architecturally complex polycyclic fused indolines is achieved in a chemo-, regio-, and stereodefined manner, via an enantioselective gold-catalyzed cascade hydroindolination/iminium trapping synthetic sequence. Highly functionalized tetracyclic fused furoindolines (2) and dihydropyranylindolines (4) are synthesized in moderate to good yields and enantiomeric excesses of up to 87%.
authors.affiliation: Department of Chemistry, G. Ciamician, Alma Mater Studiorum - University of Bologna, via Selmi 2, 40126 Bologna, Italy.
authors.forename: Gianpiero
authors.initials: G
authors.lastname: Cera
authors.forename: Michel
authors.initials: M
authors.lastname: Chiarucci
authors.forename: Andrea
authors.initials: A
authors.lastname: Mazzanti
authors.forename: Michele
authors.initials: M
authors.lastname: Mancinelli
authors.forename: Marco
authors.initials: M
authors.lastname: Bandini