title: Halogenated chamigrane sesquiterpenes from Laurencia okamurae.
abstract: Three new halogenated chamigrane sesquiterpenes, laurokamin A (1), laurokamin B (2), and laurokamin C (3), and four known halogenated chamigrane sesquiterpenes, 10-bromo-α-chamigrene (4), 10-bromo-β-chamigrene (5), 2,10-dibromo-3-chloro-β-chamigrene (6), and obtusane (7), were isolated from the marine red alga Laurencia okamurae collected from the coast of Rongcheng, China. The structures of these compounds were unambiguously identified by one- and two-dimensional NMR and mass spectroscopic methods. The antimicrobial activity of compounds 1-3 was evaluated.
authors.affiliation: Gansu Agricultural University, Lanzhou, 730070, China; Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences, Yantai, 264003, China.
authors.forename: Xiao-Dong
authors.initials: XD
authors.lastname: Li
authors.forename: Wei
authors.initials: W
authors.lastname: Ding
authors.forename: Feng-Ping
authors.initials: FP
authors.lastname: Miao
authors.forename: Nai-Yun
authors.initials: NY
authors.lastname: Ji
mesh_terms: D059001:Aquatic Organisms; D020231:Colletotrichum / Q000187:drug effects / Q000254:growth & development; D004926:Escherichia coli / Q000187:drug effects / Q000254:growth & development; D005670:Fusarium / Q000187:drug effects / Q000254:growth & development; D044722:Laurencia / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010936:Plant Extracts / Q000737:chemistry*; D012717:Sesquiterpenes / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D013211:Staphylococcus aureus / Q000187:drug effects / Q000254:growth & development
chemical_list: D010936:Plant Extracts; D012717:Sesquiterpenes