title: Virtual simulation of mouse anatomy and procedural techniques.
abstract: Translational science requires the use of mouse models for the characterization of disease and evaluation of treatment therapies. However, often there is a lack of comprehensive training for scientists in the systemic and regional anatomy of the mouse that limits their ability to perform studies involving complex interventional procedures. We present our methodologies for the development, evaluation, and dissemination of an interactive 3D mouse atlas that includes designs for presenting emulation of procedural technique. We present the novel integration of super-resolution imaging techniques, depth-of-field interactive volume rendering of large data, and the seamless delivery of remote visualization and interaction to thin clients.
authors.affiliation: Department of Biomedical Informatics, The Ohio State University, Columbus, Ohio, USA.
authors.forename: Don
authors.initials: D
authors.lastname: Stredney
authors.forename: Bradley
authors.initials: B
authors.lastname: Hittle
authors.forename: Chun-Ming
authors.initials: CM
authors.lastname: Chen
authors.forename: Thomas
authors.initials: T
authors.lastname: Kerwin
authors.forename: Anna
authors.initials: A
authors.lastname: Bratasz
authors.forename: Niranchana
authors.initials: N
authors.lastname: Manivannan
authors.forename: Kimerly
authors.initials: K
authors.lastname: Powell
mesh_terms: D000715:Anatomy; D000818:Animals; D003198:Computer Simulation; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D021621:Imaging, Three-Dimensional; D051379:Mice