title: Correlation of visually evoked intrinsic optical signals and electroretinograms recorded from chicken retina with a combined functional optical coherence tomography and electroretinography system.
abstract: Visually evoked fast intrinsic optical signals (IOSs) were recorded for the first time in vivo from all layers of healthy chicken retina by using a combined functional optical coherence tomography (fOCT) and electroretinography (ERG) system. The fast IOSs were observed to develop within ∼5 ms from the on-set of the visual stimulus, whereas slow IOSs were measured up to 1 s later. The visually evoked IOSs and ERG traces were recorded simultaneously, and a clear correlation was observed between them. The ability to measure visually evoked fast IOSs non-invasively and in vivo from individual retinal layers could significantly improve the understanding of the complex communication between different retinal cell types in healthy and diseased retinas.
authors.affiliation: University of Waterloo, Department of Physics and Astronomy, 200 University Avenue West, Waterloo, Ontario N2L3G1, Canada.
authors.forename: Alireza
authors.initials: A
authors.lastname: Akhlagh Moayed
authors.forename: Sepideh
authors.initials: S
authors.lastname: Hariri
authors.forename: Vivian
authors.initials: V
authors.lastname: Choh
authors.forename: Kostadinka
authors.initials: K
authors.lastname: Bizheva
mesh_terms: D000818:Animals; D002645:Chickens; D004596:Electroretinography / Q000379:methods*; D005074:Evoked Potentials, Visual / Q000502:physiology*; D012160:Retina / Q000502:physiology*; D012815:Signal Processing, Computer-Assisted; D041623:Tomography, Optical Coherence / Q000379:methods*