title: Pulmonary functions in patients with subclinical hypothyroidism.
abstract: OBJECTIVE
  To determine whether alterations in pulmonary function takes place in subclinical hypothyroidism by examining the diffusion lung capacity and muscle strength of such patients.
  
  
  METHODS
  This is a descriptive study conducted in 2009 at Haseki Training and Research Hospital, Istanbul, Turkey. Hundred and twenty-six patients with subclinical hypothyroidism and 58 age and sex matched individuals were recruited. Simple spirometry tests were performed, and pulmonary diffusion capacity (DLco) and muscle strength were measured.
  
  
  RESULTS
  ScH patients showed a significant reduciton of the following pulmonary function tests (% predicted value) as compared with control subjects: FVC, FEV1, FEV1%, FEF25-75, FEF25-75%, DLco, DLco/VA, Pimax, Pimax% and Pemax%.
  
  
  CONCLUSIONS
  These data indicate that pulmonary functions are effected in subclinical hypothyrodism. Therefore patients with or who are at high risk of having subclinical hypothyroidism, should be subjected to evaluation of pulmonary functions with simple spirometry.
authors.affiliation: 4th Clinic of Internal Medicine, Haseki Training and Research Hospital, Haseki Millet Caddesi, Aksaray, Turkey.
authors.forename: Gulfidan
authors.initials: G
authors.lastname: Cakmak
authors.forename: Tayyibe
authors.initials: T
authors.lastname: Saler
authors.forename: Zuhal Aydan
authors.initials: ZA
authors.lastname: Saglam
authors.forename: Mustafa
authors.initials: M
authors.lastname: Yenigun
authors.forename: Esra
authors.initials: E
authors.lastname: Ataoglu
authors.forename: Tuncalp
authors.initials: T
authors.lastname: Demir
authors.forename: Levent Umit
authors.initials: LU
authors.lastname: Temiz
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D007037:Hypothyroidism / Q000503:physiopathology*; D008168:Lung / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D053580:Muscle Strength; D011653:Pulmonary Diffusing Capacity; D012720:Severity of Illness Index; D013147:Spirometry / Q000379:methods