title: [Morphine addiction in non-human primates using rhesus monkeys].
abstract: We showed that rhesus monkeys (Macaca mulatta) can develop a morphine dependence. Rhesus monkeys successfully established a conditioned place preference (CPP) induced by morphine treatment and this preference lasted for at least (36.3 ± 1.3) months. This animal model may be useful for research into addiction in humans.
authors.affiliation: Chinese Academy of Sciences, Kunming, China.
authors.forename: Xu-Jun
authors.initials: XJ
authors.lastname: Wu
authors.forename: Wei
authors.initials: W
authors.lastname: Zong
authors.forename: Yong-Mei
authors.initials: YM
authors.lastname: Sun
authors.forename: Xin-Tian
authors.initials: XT
authors.lastname: Hu
authors.forename: Yuan-Ye
authors.initials: YY
authors.lastname: Ma
authors.forename: Jian-Hong
authors.initials: JH
authors.lastname: Wang
mesh_terms: D000818:Animals; D003216:Conditioning, Operant / Q000187:drug effects*; D004195:Disease Models, Animal; D006801:Humans; D008253:Macaca mulatta; D009020:Morphine / Q000009:adverse effects*; D009021:Morphine Dependence / Q000209:etiology / Q000523:psychology*
chemical_list: D009020:Morphine