title: [Chronic kidney disease what is it?].
abstract: Chronic kidney disease is defined by a reduced GFR (< 60 mL/min/1,73 m2) and/or the presence markers of renal injury for > or = 3 months. Chronic kidney disease indicates and increased risk of both end stage renal disease and cardiovascular mortality. The future challenge is to build a definition that would take into account patients age, rate of GFR decline and proteinuria in order to better delineate the fate of patients with chronic kidney disease, and to better differenciate physiological and pathological reduction in GFR.
authors.affiliation: Département de néphrologie-transplantation, hôpital Necker, 75743 Paris Cedex 15. doume.joly@gmail.com
authors.forename: Dominique
authors.initials: D
authors.lastname: Joly
mesh_terms: D000367:Age Factors; D000419:Albuminuria / Q000652:urine; D015415:Biomarkers / Q000652:urine; D002318:Cardiovascular Diseases / Q000401:mortality / Q000517:prevention & control; D018450:Disease Progression; D005602:France / Q000453:epidemiology; D005919:Glomerular Filtration Rate; D006801:Humans; D007676:Kidney Failure, Chronic / Q000175:diagnosis; D007677:Kidney Function Tests; D011379:Prognosis; D051436:Renal Insufficiency, Chronic / Q000150:complications / Q000175:diagnosis* / Q000378:metabolism* / Q000401:mortality / Q000503:physiopathology / Q000652:urine; D012307:Risk Factors
chemical_list: D015415:Biomarkers