title: Reversible isolated sensory axonal neuropathy due to cobalamin deficiency.
abstract: Vitamin B(12) deficiency causes a wide range of hematological, gastrointestinal, and neurological manifestations. The most common neurological complication is subacute combined degeneration, sometimes associated with polyneuropathy. Isolated peripheral neuropathy due to cyanocobalamin deficiency is less frequent, and thus it may be overlooked. We describe 2 patients with isolated sensory axonal neuropathy secondary to vitamin B(12) deficiency who had complete clinical and electrophysiological recovery after cyanocobalamin replacement. Testing for serum vitamin B(12) and its metabolites should be done in any distal symmetric neuropathy.
authors.affiliation: Department of Neuroscience, University of Padova, Via Giustiniani 5, 35128 Padova, Italy.
authors.forename: Chiara
authors.initials: C
authors.lastname: Dalla Torre
authors.forename: Marta
authors.initials: M
authors.lastname: Lucchetta
authors.forename: Mario
authors.initials: M
authors.lastname: Cacciavillani
authors.forename: Marta
authors.initials: M
authors.lastname: Campagnolo
authors.forename: Renzo
authors.initials: R
authors.lastname: Manara
authors.forename: Chiara
authors.initials: C
authors.lastname: Briani
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008875:Middle Aged; D009431:Neural Conduction / Q000187:drug effects / Q000502:physiology; D010523:Peripheral Nervous System Diseases / Q000188:drug therapy / Q000209:etiology*; D014805:Vitamin B 12 / Q000494:pharmacology / Q000627:therapeutic use*; D014806:Vitamin B 12 Deficiency / Q000150:complications*; D014803:Vitamin B Complex / Q000494:pharmacology / Q000627:therapeutic use
chemical_list: D014803:Vitamin B Complex; D014805:Vitamin B 12