title: SAMHD1 Joins the red Queen's court.
abstract: The host restriction factor SAMHD1 hinders lentiviral infection of myeloid cells, a function counteracted by the viral protein Vpx. Two papers in this issue of Cell Host & Microbe document the genetic conflict between SAMHD1 and the Vpr/Vpx proteins, which has subjected SAMHD1 to intense periods of diversifying selection through primate evolution.
authors.affiliation: Division of Microbiology and Immunology, Department of Pathology, University of Utah School of Medicine, Emma Eccles Jones Building, 15 North Medical Drive East #2100, Room 2520, Salt Lake City, UT 84112, USA. vicente.planelles@path.utah.edu
authors.forename: Vicente
authors.initials: V
authors.lastname: Planelles