title: Manifestation of leukoencephalopathy in a patient with advanced non-small cell lung cancer following treatment with gefitinib.
abstract: The present case is a patient with advanced non-small cell lung cancer (NSCLC) who developed leukoencephalopathy following radiotherapy and gefitinib treatments. There are rarely reports of such incidences because the median survival period of advanced NSCLC is only ten months. The features of leukoencephalopathy in this case were atypical for radiation leukoencephalopathy, so it was suspected that the leukoencephalopathy was associated with gefitinib.
authors.affiliation: Guangdong Lung Cancer Institute, Guangdong General Hospital and Guangdong Academy of Medical Sciences, Guangzhou, Guangdong 510080, China.
authors.forename: Yi-Sheng
authors.initials: YS
authors.lastname: Huang
authors.forename: Biao
authors.initials: B
authors.lastname: Huang
authors.forename: Yi-Long
authors.initials: YL
authors.lastname: Wu
mesh_terms: D002289:Carcinoma, Non-Small-Cell Lung / Q000188:drug therapy*; D005260:Female; D000077156:Gefitinib; D006801:Humans; D056784:Leukoencephalopathies / Q000139:chemically induced / Q000175:diagnosis*; D008175:Lung Neoplasms / Q000188:drug therapy*; D008875:Middle Aged; D011799:Quinazolines / Q000009:adverse effects* / Q000627:therapeutic use
chemical_list: D011799:Quinazolines; D000077156:Gefitinib