title: [The value of extra-lung lesions on ¹⁸F-FDG PET/CT in improving diagnosis of lung cancer].
abstract: OBJECTIVE
  ¹⁸F-FDG PET/CT has several shortcomings in discriminating between lung carcinoma and pulmonary benign lesions. The aims of the present study is to explore the value of extra-lung lesions on ¹⁸F-FDG PET/CT image in the diagnosis of lung cancer.
  
  
  METHODS
  A total of 126 suspected lung cancer patients underwent ¹⁸F-FDG PET/CT scan. Preliminary diagnoses were based on the PET characteristics, SUVmean value, and CT characteristics of the lesions in the lung, and the diagnoses were modified based on the detected extra-lung lesions. The difference between the two methods and their disparity were calculated.
  
  
  RESULTS
  Extra-lung lesions were identified on the PET/CT image in 81 patients; extra-lung metastasis modified 13 probable malignancies to affirmative malignancy and 1 probable malignancy to benign lesion. Non-metastasis modified 2 probable malignancies to affirmative malignancy and 1 probable malignancy to benign lesion. Fifteen were correct, whereas 2 were misdiagnosed. The diagnoses modification rate was 13.5% (17/126), and the modified diagnoses accuracy is 88.2% (15/17).
  
  
  CONCLUSIONS
  Extra-lung lesions demonstrated on ¹⁸F-FDG PET/CT improved the diagnostic accuracy of lung cancer. Tuberculosis was identified as the most important reason for false positive diagnoses after modification by extra-lung lesions.
authors.affiliation: Department of Nuclear Medicine, the Fourth Affiliated Hospital of Soochow University, Wuxi 214062, China.
authors.forename: Baoming
authors.initials: B
authors.lastname: Mi
authors.forename: Weixing
authors.initials: W
authors.lastname: Wan
authors.forename: Chunjing
authors.initials: C
authors.lastname: Yu
authors.forename: Xuyang
authors.initials: X
authors.lastname: You
authors.forename: Feng
authors.initials: F
authors.lastname: Jiang
authors.forename: Qingjun
authors.initials: Q
authors.lastname: You
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D064847:Multimodal Imaging / Q000379:methods*; D049268:Positron-Emission Tomography; D014057:Tomography, X-Ray Computed; D055815:Young Adult
chemical_list: D019788:Fluorodeoxyglucose F18