title: Oestrogen-related tumour phenotype: positron emission tomography characterisation with ¹⁸F-FDG and ¹⁸F-FES.
abstract: This article outlines the role of 16α-[(18)F]fluoro-17β-oestradiol ((18)F-FES) positron emission tomography (PET) combined with 2-[(18)F]fluoro-2-deoxy-D-glucose ((18)F-FDG) in patients with oestrogen-related tumours for evaluating tumour phenotype. (18)F-FES-PET combined with (18)F-FDG is helpful in characterising the distinct phenotypic features of oestrogen-related tumours; that is, inter- and intrapatient tumour heterogeneity, which indicates its great potential as a determinant of individualised treatment and a prognostic predictor for patients with oestrogen-related tumours.
authors.affiliation: Biomedical Imaging Research Center, University of Fukui, Fukui, Japan, University of Fukui, Fukui, Japan. awaji@u-fukui.ac.jp
authors.forename: T
authors.initials: T
authors.lastname: Tsujikawa
authors.forename: Y
authors.initials: Y
authors.lastname: Yoshida
authors.forename: H
authors.initials: H
authors.lastname: Maeda
authors.forename: T
authors.initials: T
authors.lastname: Tsuchida
authors.forename: T
authors.initials: T
authors.lastname: Mori
authors.forename: Y
authors.initials: Y
authors.lastname: Kiyono
authors.forename: H
authors.initials: H
authors.lastname: Kimura
authors.forename: H
authors.initials: H
authors.lastname: Okazawa
mesh_terms: D000368:Aged; D001943:Breast Neoplasms / Q000000981:diagnostic imaging* / Q000235:genetics / Q000601:surgery; D003287:Contrast Media; D016889:Endometrial Neoplasms / Q000000981:diagnostic imaging* / Q000235:genetics / Q000601:surgery; D004967:Estrogens / Q000378:metabolism*; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D007089:Image Enhancement; D008875:Middle Aged; D009376:Neoplasms, Hormone-Dependent / Q000000981:diagnostic imaging* / Q000235:genetics / Q000601:surgery; D010641:Phenotype; D049268:Positron-Emission Tomography / Q000379:methods*; D012680:Sensitivity and Specificity
chemical_list: D003287:Contrast Media; D004967:Estrogens; D019788:Fluorodeoxyglucose F18