title: Effects of a sliding plate on morphology of the epiphyseal plate in goat distal femur.
abstract: The aim of this study was to observe the effects of a sliding plate on the morphology of the epiphyseal plate in goat distal femur. Eighteen premature female goats were divided randomly into sliding plate, regular plate and control groups. Radiographic analysis and histological staining were performed to evaluate the development of epiphyseal plate at 4 and 8 weeks after surgery. In the sliding plate group, the plate extended accordingly as the epiphyseal plate grows, and the epiphyseal morphology was kept essential normal. However, the phenomenon of the epiphyseal growth retardation and premature closure were very common in the regular plate group. In addition, the sliding plate group exhibited more normal histologic features and Safranin O staining compared to the regular plate group. Our results suggest that the sliding plate can provide reliable internal fixation of epiphyseal fracture without inhibiting epiphyseal growth.
authors.affiliation: Department of Orthopaedic Surgery, the Affiliated Southeast Hospital of Xiamen University, Orthopaedic Center of People's Liberation Army, Zhangzhou 363000, China.
authors.forename: Da-sheng
authors.initials: DS
authors.lastname: Lin
authors.forename: Ke-jian
authors.initials: KJ
authors.lastname: Lian
authors.forename: Jia-yuan
authors.initials: JY
authors.lastname: Hong
authors.forename: Zhen-qi
authors.initials: ZQ
authors.lastname: Ding
authors.forename: Wen-liang
authors.initials: WL
authors.lastname: Zhai
mesh_terms: D000818:Animals; D001860:Bone Plates / Q000009:adverse effects; D001864:Bone Wires; D002452:Cell Count; D004867:Equipment Design; D005260:Female; D005269:Femur / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D006041:Goats; D006132:Growth Plate / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D020007:Implants, Experimental / Q000009:adverse effects; D016268:Internal Fixators / Q000009:adverse effects; D010619:Phenazines; D011183:Postoperative Complications / Q000517:prevention & control; D011859:Radiography; D011897:Random Allocation; D000072042:Salter-Harris Fractures; D013194:Staining and Labeling
chemical_list: D010619:Phenazines; C009195:safranine T