title: Three-dimensional brain images in preterm children with periventricular leukomalacia.
abstract: BACKGROUND
  To investigate the use of three-dimensional (3D) brain magnetic resonance imaging (MRI) to evaluate in preterm children with periventricular leukomalacia.
  
  
  METHODS
  Semiautomated 3D classification of the gray and white tissues was used to reconstruct brain images of patients with confirmed periventricular leukomalacia from 2D MRI.
  
  
  RESULTS
  We studied 14 preterm patients. The gestational age ranged from 25-37 weeks. The corrected age ranged from 5-49 months. We reconstructed the gray matter, white matter, and ventricles in order to analyze the brain volume.
  
  
  CONCLUSIONS
  Three-dimensional MRI is a good tool that can be used to demonstrate brain lesions in stereo and differentiate the gray matter, white matter, and ventricles. Brain volume can also be accurately evaluated.
authors.affiliation: Department of Pediatrics, Taipei Medical University-Wan Fang Hospital, Taipei, Taiwan.
authors.forename: Hsiao-Feng
authors.initials: HF
authors.lastname: Chou
authors.forename: Ming-Fan
authors.initials: MF
authors.lastname: Lin
authors.forename: Chia-Yuan
authors.initials: CY
authors.lastname: Chen
authors.forename: Ein-Yiao
authors.initials: EY
authors.lastname: Shen
mesh_terms: D001724:Birth Weight; D001921:Brain / Q000473:pathology*; D005260:Female; D005865:Gestational Age; D006801:Humans; D007091:Image Processing, Computer-Assisted; D021621:Imaging, Three-Dimensional; D007231:Infant, Newborn; D007234:Infant, Premature; D007235:Infant, Premature, Diseases / Q000175:diagnosis*; D007969:Leukomalacia, Periventricular / Q000150:complications / Q000175:diagnosis*; D008279:Magnetic Resonance Imaging; D008297:Male; D010264:Paraplegia / Q000209:etiology; D011782:Quadriplegia / Q000209:etiology