title: Efficient syntheses of 2,3-disubstituted natural quinazolinones via iridium catalysis.
abstract: Natural products sclerotigenin, pegamine, deoxyvasicinone, mackinazolinone, and rutaecarpine were synthesized. Core quinazolinone structures were constructed via Ir catalysis.
authors.affiliation: Chemical and Analytical Development, Suzhou Novartis Pharma Technology Co. Ltd, Changshu, Jiangsu, China 215537.
authors.forename: Jie
authors.initials: J
authors.lastname: Fang
authors.forename: Jianguang
authors.initials: J
authors.lastname: Zhou
mesh_terms: D002384:Catalysis; D003500:Cyclization; D007495:Iridium / Q000737:chemistry*; D015394:Molecular Structure; D010084:Oxidation-Reduction; D052999:Quinazolinones / Q000138:chemical synthesis*
chemical_list: D052999:Quinazolinones; D007495:Iridium