title: [Ghrelin secretion in patients, operated on cholelithiasis].
abstract: The grelin blood level was measured on 54 patients, of whom 18 were healthy volunteers; 20 patients with cholecystolithiasis had been measured perioperatively during the cholecystectomy; and the rest 16 patients of the study group had had cholecystectomy 2-15 years ago. All patients demonstrated perioperative hypergrelinemy with the normalization of the grelin level during the long-term follow-up. Grelin is considered to have certain immunomodulating and anti-inflammatory effects, thus improving the postoperative regeneration. Therefore, the increase of grelin blood level during the perioperative period is considered to be a defense reaction.
authors.forename: I V
authors.initials: IV
authors.lastname: Tereshchenko
authors.forename: P E
authors.initials: PE
authors.lastname: Kaiushev
mesh_terms: D000328:Adult; D002763:Cholecystectomy / Q000009:adverse effects / Q000379:methods; D002769:Cholelithiasis / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D054439:Ghrelin / Q000097:blood*; D006801:Humans; D056747:Immunomodulation; D007249:Inflammation / Q000209:etiology / Q000378:metabolism; D008297:Male; D019990:Perioperative Care / Q000379:methods; D011183:Postoperative Complications / Q000209:etiology / Q000276:immunology / Q000378:metabolism; D011184:Postoperative Period; D013995:Time; D014945:Wound Healing
chemical_list: D054439:Ghrelin