title: NO serves as a signaling intermediate downstream of H₂O₂ to modulate dynamic microtubule cytoskeleton during responses to VD-toxins in Arabidopsis.
abstract: Although hydrogen peroxide (H₂O₂) and nitric oxide (NO) can act as an upstream signaling molecule to modulate the dynamic microtubule cytoskeleton during the defense responses to Verticillium dahliae (VD) toxins in Arabidopsis, it is not known the relationship between these two signaling molecules. Here, we show that VD-toxin-induced NO accumulation was dependent on prior H₂O₂ production, NO is downstream of H₂O₂ in the signaling process, and that H₂O₂ acted synergistically with NO to modulate the dynamic microtubule cytoskeleton responses to VD-toxins in Arabidopsis.
authors.affiliation: State Key Laboratory of Plant Physiology and Biochemistry, College of Biological Sciences, China Agricultural University, Beijing, China.
authors.forename: Lin-Lin
authors.initials: LL
authors.lastname: Yao
authors.forename: Bao-Lei
authors.initials: BL
authors.lastname: Pei
authors.forename: Qun
authors.initials: Q
authors.lastname: Zhou
authors.forename: Ying-Zhang
authors.initials: YZ
authors.lastname: Li
mesh_terms: D017360:Arabidopsis / Q000187:drug effects* / Q000378:metabolism / Q000382:microbiology; D003599:Cytoskeleton / Q000187:drug effects* / Q000378:metabolism; D006861:Hydrogen Peroxide / Q000378:metabolism*; D008870:Microtubules / Q000187:drug effects / Q000378:metabolism; D009183:Mycotoxins / Q000494:pharmacology*; D009569:Nitric Oxide / Q000378:metabolism*; D010935:Plant Diseases / Q000382:microbiology; D057865:Plant Immunity / Q000502:physiology*; D015398:Signal Transduction; D020172:Verticillium / Q000378:metabolism*
chemical_list: D009183:Mycotoxins; D009569:Nitric Oxide; D006861:Hydrogen Peroxide