title: A comprehensive cardiac motion estimation framework using both untagged and 3-D tagged MR images based on nonrigid registration.
abstract: In this paper, we present a novel technique based on nonrigid image registration for myocardial motion estimation using both untagged and 3-D tagged MR images. The novel aspect of our technique is its simultaneous usage of complementary information from both untagged and 3-D tagged MR images. To estimate the motion within the myocardium, we register a sequence of tagged and untagged MR images during the cardiac cycle to a set of reference tagged and untagged MR images at end-diastole. The similarity measure is spatially weighted to maximize the utility of information from both images. In addition, the proposed approach integrates a valve plane tracker and adaptive incompressibility into the framework. We have evaluated the proposed approach on 12 subjects. Our results show a clear improvement in terms of accuracy compared to approaches that use either 3-D tagged or untagged MR image information alone. The relative error compared to manually tracked landmarks is less than 15% throughout the cardiac cycle. Finally, we demonstrate the automatic analysis of cardiac function from the myocardial deformation fields.
authors.affiliation: Department of Computing, Imperial College, SW7 2AZ London, UK. trustswz@gmail.com
authors.forename: Wenzhe
authors.initials: W
authors.lastname: Shi
authors.forename: Xiahai
authors.initials: X
authors.lastname: Zhuang
authors.forename: Haiyan
authors.initials: H
authors.lastname: Wang
authors.forename: Simon
authors.initials: S
authors.lastname: Duckett
authors.forename: Duy V N
authors.initials: DV
authors.lastname: Luong
authors.forename: Catalina
authors.initials: C
authors.lastname: Tobon-Gomez
authors.forename: Kaipin
authors.initials: K
authors.lastname: Tung
authors.forename: Philip J
authors.initials: PJ
authors.lastname: Edwards
authors.forename: Kawal S
authors.initials: KS
authors.lastname: Rhode
authors.forename: Reza S
authors.initials: RS
authors.lastname: Razavi
authors.forename: Sebastien
authors.initials: S
authors.lastname: Ourselin
authors.forename: Daniel
authors.initials: D
authors.lastname: Rueckert
mesh_terms: D000465:Algorithms; D055424:Cardiac-Gated Imaging Techniques / Q000379:methods; D006801:Humans; D021621:Imaging, Three-Dimensional / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D009068:Movement / Q000502:physiology*; D009200:Myocardial Contraction / Q000502:physiology*; D010363:Pattern Recognition, Automated / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013382:Subtraction Technique; D016277:Ventricular Function, Left / Q000502:physiology*