title: Allylic alkylations catalyzed by palladium-bis(oxazoline) complexes derived from heteroarylidene malonate derivatives.
abstract: A series of simple heteroarylidene malonate-type bis(oxazoline) ligands 4 and 5 were applied to the palladium-catalyzed allylic alkylation reaction, and the ligand 4a bearing a phenyl group afforded excellent enantioselectivity (up to 96% ee) for the allylic alkylation product. Other substrates were also examined, giving the allylic alkylated products in high yield but with poor ee values.
authors.affiliation: Department of Applied Chemistry, China Agricultural University, Beijing 100193, China.
authors.forename: Lei
authors.initials: L
authors.lastname: Liu
authors.forename: Hongli
authors.initials: H
authors.lastname: Ma
authors.forename: Bin
authors.initials: B
authors.lastname: Fu
mesh_terms: D000478:Alkylation; D000498:Allyl Compounds / Q000737:chemistry*; D002384:Catalysis; D008024:Ligands; D008314:Malonates / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*
chemical_list: D000498:Allyl Compounds; D008024:Ligands; D008314:Malonates; D010165:Palladium