title: Omic techniques in systems biology approaches to traditional Chinese medicine research: present and future.
abstract: Omic techniques have become key tools in the development of systems biology. As the holistic approaches underlying the practice of traditional Chinese medicine (TCM) and new tendencies in Western medicine towards personalised medicine require in-depth knowledge of mechanisms of action and active compounds, the use of omic techniques is crucial for understanding and interpretation of TCM development, especially in view of its expansion in Western countries. In this short review, omic applications in TCM research are reviewed which has allowed some speculation regarding future perspectives for these approaches in TCM modernisation and standardisation. Guidelines for good practice for the application of omics in TCM research are also proposed.
authors.affiliation: Institute of Pharmaceutical Science, King's College London, Franklin-Wilkins Building, 150 Stamford Street, London, SE1 9NH, UK.
authors.forename: Alessandro
authors.initials: A
authors.lastname: Buriani
authors.forename: Maria L
authors.initials: ML
authors.lastname: Garcia-Bermejo
authors.forename: Enrica
authors.initials: E
authors.lastname: Bosisio
authors.forename: Qihe
authors.initials: Q
authors.lastname: Xu
authors.forename: Huige
authors.initials: H
authors.lastname: Li
authors.forename: Xuebin
authors.initials: X
authors.lastname: Dong
authors.forename: Monique S J
authors.initials: MS
authors.lastname: Simmonds
authors.forename: Maria
authors.initials: M
authors.lastname: Carrara
authors.forename: Noelia
authors.initials: N
authors.lastname: Tejedor
authors.forename: Javier
authors.initials: J
authors.lastname: Lucio-Cazana
authors.forename: Peter J
authors.initials: PJ
authors.lastname: Hylands
mesh_terms: D035843:Biomedical Research / Q000379:methods; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use*; D029001:Herbal Medicine / Q000379:methods*; D006801:Humans; D008516:Medicine, Chinese Traditional; D008517:Phytotherapy; D010946:Plants, Medicinal / Q000737:chemistry*; D057285:Precision Medicine / Q000379:methods*; D049490:Systems Biology / Q000379:methods*; D013678:Technology, Pharmaceutical / Q000379:methods
chemical_list: D004365:Drugs, Chinese Herbal