title: Burden of invasive cervical cancer in North Carolina.
abstract: OBJECTIVE
  Cervical cancer causes over 4000 deaths yearly in the United States, although highly preventable through vaccination, screening, and early treatment. We aimed to determine demographic correlates for cervical cancer in North Carolina to identify target populations for interventions and to create a framework for state-level analyses.
  
  
  METHODS
  Data on all reported invasive cervical cancer cases from 1998 to 2007 were obtained from the North Carolina Central Cancer Registry. Age-adjusted incidence and mortality rates were estimated using population data from the National Center for Health Statistics.
  
  
  RESULTS
  Cervical cancer incidence and mortality rates varied greatly by county and were inversely associated with county prosperity. Hispanic women had the highest incidence rate, black women the highest mortality rate, although white women accounted for most cases. Incidence rates remained fairly steady above age 35 and mortality rates steadily increased with age. A later stage at diagnosis was more common for older women and for women without private insurance.
  
  
  CONCLUSIONS
  Registry-based assessment illustrates the economic, racial, and age disparities associated with cervical cancer. This localized focus on demographic correlates is an important step toward eliminating this preventable disease and offers a template for cervical cancer prevention programs in other states.
authors.affiliation: Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC 27599, USA. sheri.denslow@msj.org
authors.forename: Sheri A
authors.initials: SA
authors.lastname: Denslow
authors.forename: Gabriel
authors.initials: G
authors.lastname: Knop
authors.forename: Christian
authors.initials: C
authors.lastname: Klaus
authors.forename: Noel T
authors.initials: NT
authors.lastname: Brewer
authors.forename: Chandrika
authors.initials: C
authors.lastname: Rao
authors.forename: Jennifer S
authors.initials: JS
authors.lastname: Smith
mesh_terms: D000230:Adenocarcinoma / Q000453:epidemiology / Q000401:mortality; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000453:epidemiology / Q000401:mortality; D017281:Cost of Illness; D005260:Female; D006801:Humans; D015994:Incidence; D017057:Medically Uninsured / Q000706:statistics & numerical data; D008875:Middle Aged; D009657:North Carolina; D044469:Racial Groups / Q000706:statistics & numerical data; D012042:Registries; D012307:Risk Factors; D012959:Socioeconomic Factors; D002583:Uterine Cervical Neoplasms / Q000453:epidemiology* / Q000401:mortality; D055815:Young Adult