title: Integra Bilayer Matrix Wound Dressing closure of large periorbital traumatic wound.
abstract: We report the first use of the Integra Bilayer Matrix Wound Dressing (Integra LifeSciences Corp), a collagen sheet with glycosaminoglycans and a silicone layer, in an innovative reconstruction approach to devastating traumatic tissue loss in the periocular area. A 36-year-old woman was involved in a motor vehicle crash with a resultant large defect from the medial canthus to the temporal fossa and from the pretarsal skin to the brow. There was denudation of skin and soft tissue to the bone at the superolateral orbital apex. The severity of tissue loss precluded placement of an autograft or allograft; thus, a skin substitute was instead used, with a successful reconstructive outcome. Application of the newer bioengineered skin products for full-thickness skin wounds should be considered for reconstruction of the periocular area.
authors.affiliation: Vanderbilt Eye Institute, Nashville, TN 37232-8808, USA.
authors.forename: Sumeer
authors.initials: S
authors.lastname: Thinda
authors.forename: Harry V
authors.initials: HV
authors.lastname: Wright
authors.forename: Louise A
authors.initials: LA
authors.lastname: Mawn
mesh_terms: D000063:Accidents, Traffic; D000328:Adult; D002809:Chondroitin Sulfates; D003094:Collagen; D005131:Eye Injuries / Q000601:surgery*; D005143:Eyelids / Q000293:injuries*; D005260:Female; D006801:Humans; D009915:Orbit / Q000293:injuries*; D011126:Polypropylenes; D019651:Plastic Surgery Procedures; D016038:Skin Transplantation; D017695:Soft Tissue Injuries / Q000601:surgery*; D013536:Suture Techniques; D013537:Sutures; D014182:Transplantation, Autologous; D014945:Wound Healing; D015051:Zygomatic Fractures / Q000601:surgery*
chemical_list: D011126:Polypropylenes; C114835:integra artificial skin; D002809:Chondroitin Sulfates; D003094:Collagen