title: Chemotaxis: movement, direction, control.
abstract: This review focuses on basic principles of motility in different cell types, formation of the specific cell structures that enable directed migration, and how external signals are transduced into cells and coupled to the motile machinery. Feedback mechanisms and their potential role in maintenance of internal chemotactic gradients and persistence of directed migration are highlighted.
authors.affiliation: Department of Biochemistry and Molecular Medicine, Lomonosov Moscow State University, Moscow, Russia. vorotnikov@fbm.msu.ru
authors.forename: A V
authors.initials: AV
authors.lastname: Vorotnikov
mesh_terms: D000818:Animals; D002448:Cell Adhesion; D002462:Cell Membrane / Q000378:metabolism; D016764:Cell Polarity; D002633:Chemotaxis; D003598:Cytoskeletal Proteins / Q000378:metabolism; D004023:Dictyostelium / Q000166:cytology / Q000378:metabolism / Q000502:physiology; D025461:Feedback, Physiological; D005347:Fibroblasts / Q000166:cytology / Q000378:metabolism / Q000502:physiology; D006801:Humans; D007962:Leukocytes / Q000166:cytology / Q000378:metabolism / Q000502:physiology; D015398:Signal Transduction
chemical_list: D003598:Cytoskeletal Proteins