title: Comparative vibration levels perceived among species in a laboratory animal facility.
abstract: The current study was performed to determine the vibration levels that were generated in cages on a ventilated rack by common construction equipment in frequency ranges likely to be perceived by humans, rats, and mice. Vibration generated by the ventilated rack blower caused small but significant increases in some of the abdominal, thoracic, and head resonance frequency ranges (RFR) and sensitivity frequency ranges (SFR) in which each species is most likely to be affected by and perceive vibration, respectively. Vibration caused by various items of construction equipment at 3 ft from the cage were evaluated relative to the RFR and SFR of humans, rats, and mice in 3 anatomic locations. In addition, the vibration levels in the RFR and SFR that resulted from the use of a large jackhammer and were measured at various locations and distances in the facility and evaluated in terms of humans, rats, and mice in 3 anatomic locations. Taken together, the data indicate that a given vibration source generates vibration in frequency ranges that are more likely to affect rats and mice as compared with humans.
authors.affiliation: The Division of Laboratory Animal Resources, Duke University Medical Center, Durham, North Carolina, USA. john.norton@duke.edu
authors.forename: John N
authors.initials: JN
authors.lastname: Norton
authors.forename: Will L
authors.initials: WL
authors.lastname: Kinard
authors.forename: Randall P
authors.initials: RP
authors.lastname: Reynolds
mesh_terms: D000818:Animals; D000830:Animals, Laboratory; D060389:Construction Industry / Q000295:instrumentation*; D004864:Equipment and Supplies / Q000009:adverse effects*; D005583:Fourier Analysis; D006257:Head / Q000502:physiology; D006799:Housing, Animal; D006801:Humans; D051379:Mice; D051381:Rats; D013045:Species Specificity; D060726:Torso / Q000502:physiology; D014691:Ventilation / Q000295:instrumentation*; D014732:Vibration