title: XmAb-5574 antibody demonstrates superior antibody-dependent cellular cytotoxicity as compared with CD52- and CD20-targeted antibodies in adult acute lymphoblastic leukemia cells.
authors.forename: S
authors.initials: S
authors.lastname: Rafiq
authors.forename: C
authors.initials: C
authors.lastname: Cheney
authors.forename: X
authors.initials: X
authors.lastname: Mo
authors.forename: D
authors.initials: D
authors.lastname: Jarjoura
authors.forename: N
authors.initials: N
authors.lastname: Muthusamy
authors.forename: J C
authors.initials: JC
authors.lastname: Byrd
mesh_terms: D000328:Adult; D000911:Antibodies, Monoclonal / Q000494:pharmacology*; D000920:Antibody-Dependent Cell Cytotoxicity; D015703:Antigens, CD / Q000276:immunology*; D018941:Antigens, CD19 / Q000276:immunology*; D018951:Antigens, CD20 / Q000276:immunology*; D000951:Antigens, Neoplasm / Q000276:immunology*; D000074301:CD52 Antigen; D005434:Flow Cytometry; D006023:Glycoproteins / Q000276:immunology*; D006801:Humans; D007141:Immunoglobulin Fc Fragments / Q000276:immunology* / Q000378:metabolism; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000188:drug therapy* / Q000276:immunology / Q000473:pathology; D017452:Receptors, IgG / Q000276:immunology / Q000378:metabolism
chemical_list: D000911:Antibodies, Monoclonal; D015703:Antigens, CD; D018941:Antigens, CD19; D018951:Antigens, CD20; D000951:Antigens, Neoplasm; D000074301:CD52 Antigen; C000613862:CD52 protein, human; C080571:Fc gamma receptor IIB; D006023:Glycoproteins; D007141:Immunoglobulin Fc Fragments; D017452:Receptors, IgG