title: Biomarker development: prudence, risk, and reproducibility.
abstract: Is a two-fold approach - preliminary studies based on small samples followed by a large-sample study to check reproducibility - in the search for biomarkers really prudent?
authors.affiliation: Electrical and Computer Engineering, Texas A&M University, TX, USA. edward@ece.tamu.edu
authors.forename: Edward R
authors.initials: ER
authors.lastname: Dougherty
mesh_terms: D015415:Biomarkers; D006801:Humans; D015203:Reproducibility of Results
chemical_list: D015415:Biomarkers