title: Volatile organic compounds from Centaurium erythraea Rafn (Croatia) and the antimicrobial potential of its essential oil.
abstract: GC and MS were used for the analysis of Croatian Centaurium erythraea Rafn essential oil (obtained by hydrodistillation) and headspace (applying headspace solid-phase microextraction). The headspace contained numerous monoterpene hydrocarbons (the major ones were terpinene-4-ol, methone, p-cymene, γ-terpinene and limonene). Oxygenated monoterpenes were present in the headspace and oil, while 1,8-cineole, bornyl acetate and verbenone were present only in the headspace. High headspace percentages of toluene and naphthalene were found, followed by hemimellitene. Lot of similarities were observed with Serbian C. erythraea oil [neophytadiene (1.4%), thymol (2.6%), carvacrol (6.1%) and hexadecanoic acid (5.7%)], but different features were also noted such as the presence of menthol, menthone and phytone. The oil fractionation enabled identification of other minor compounds not found in total oil such as norisoprenoides, alk-1-enes or chromolaenin. The essential oil showed antimicrobial potential on Escherichia coli, Salmonella enteritidis, Staphylococcus aureus and Bacillus cereus. On the other hand, no antibacterial activity of the oil was observed on Pseudomonas fluorescens and Lysteria monocytogenes.
authors.affiliation: Department of Organic Chemistry, Faculty of Chemistry & Technology, University of Split, N. Tesle 10/V, HR-21000 Split, Croatia. igor@ktf-split.hr
authors.forename: Igor
authors.initials: I
authors.lastname: Jerković
authors.forename: Dajana
authors.initials: D
authors.lastname: Gašo-Sokač
authors.forename: Hrvoje
authors.initials: H
authors.lastname: Pavlović
authors.forename: Zvonimir
authors.initials: Z
authors.lastname: Marijanović
authors.forename: Mirko
authors.initials: M
authors.lastname: Gugić
authors.forename: Ivana
authors.initials: I
authors.lastname: Petrović
authors.forename: Spomenka
authors.initials: S
authors.lastname: Kovač
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects*; D001555:Benzene Derivatives / Q000737:chemistry; D000081008:Bicyclic Monoterpenes; D001892:Camphanes / Q000737:chemistry; D029966:Centaurium / Q000737:chemistry*; D002849:Chromatography, Gas / Q000379:methods; D017523:Croatia; D003511:Cyclohexanols / Q000737:chemistry; D000077591:Eucalyptol; D006838:Hydrocarbons / Q000737:chemistry; D013058:Mass Spectrometry / Q000379:methods; D039821:Monoterpenes / Q000737:chemistry; D009281:Naphthalenes / Q000737:chemistry; D009822:Oils, Volatile / Q000737:chemistry* / Q000494:pharmacology*; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology; D013729:Terpenes / Q000737:chemistry; D014050:Toluene / Q000737:chemistry
chemical_list: D000900:Anti-Bacterial Agents; D001555:Benzene Derivatives; D000081008:Bicyclic Monoterpenes; D001892:Camphanes; D003511:Cyclohexanols; D006838:Hydrocarbons; D039821:Monoterpenes; D009281:Naphthalenes; D009822:Oils, Volatile; D010936:Plant Extracts; D013729:Terpenes; C071528:bornyl acetate; C031721:naphthalene; D014050:Toluene; C010179:hemimellitene; C052875:verbenone; D000077591:Eucalyptol