title: CytoSaddleSum: a functional enrichment analysis plugin for Cytoscape based on sum-of-weights scores.
abstract: CytoSaddleSum provides Cytoscape users with access to the functionality of SaddleSum, a functional enrichment tool based on sum-of-weight scores. It operates by querying SaddleSum locally (using the standalone version) or remotely (through an HTTP request to a web server). The functional enrichment results are shown as a term relationship network, where nodes represent terms and edges show term relationships. Furthermore, query results are written as Cytoscape attributes allowing easy saving, retrieval and integration into network-based data analysis workflows.
authors.affiliation: National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA.
authors.forename: Aleksandar
authors.initials: A
authors.lastname: Stojmirovic
authors.forename: Alexander
authors.initials: A
authors.lastname: Bliskovsky
authors.forename: Yi-Kuo
authors.initials: YK
authors.lastname: Yu
mesh_terms: D017353:Gene Deletion; D005796:Genes; D009317:National Library of Medicine (U.S.); D012984:Software; D014481:United States