title: Corneal Endothelium in Brown-McLean syndrome: in-vivo confocal microscopy finding.
abstract: When Brown-McLean syndrome (BMS) was first described, there was no confocal microscopy to document corneal endothelial status, and it was understood as a disease entity involving a diseased endothelial layer. In the advent of confocal microscopy demonstrating healthy endothelium in BMS within the affected cornea, it can be inferred that BMS is a spectrum of disease ranging from healthy to decompensated corneal endothelium, rather than just a specific disease entity. Here we report a case of BMS with normal healthy corneal endothelium using corneal confocal microscopy. Any patient with BMS should be followed up to observe for any disease progression and should be educated regarding the signs and symptoms of corneal surface problems. Confocal microscopy documentation is a convenient and informative way and should form part of the follow-up of any BMS patient.
authors.affiliation: Tennent Institute of Ophthalmology, Glasgow, UK. likthai@doctors.org.uk
authors.forename: Lik Thai
authors.initials: LT
authors.lastname: Lim
authors.forename: Sonali
authors.initials: S
authors.lastname: Tarafdar
authors.forename: Cian E
authors.initials: CE
authors.lastname: Collins
authors.forename: Saraswathi
authors.initials: S
authors.lastname: Ramamurthi
authors.forename: Kanna
authors.initials: K
authors.lastname: Ramaesh
mesh_terms: D000368:Aged; D015715:Corneal Edema / Q000473:pathology*; D004728:Endothelium, Corneal / Q000166:cytology*; D006801:Humans; D008297:Male; D018613:Microscopy, Confocal; D013577:Syndrome