title: [Influence of hydrophiling agents on gel formation rate on Carbopol base].
abstract: The aim of the study was to assess the impact of substrate composition on the physicochemical and pharmaceutical availability of hydrocortisone. Gels prepared on the basis of contained varying amounts of Carbopol propylene glycol-1,2, and polyethylene glycol 200. Applied hydrophilic substances affect the diversity of hydrocortisone half release times from hydrogels.
authors.affiliation: Katedra i Zakład Technologii Postaci Leku, Akademia Medyczna Wrocław. marias@ktpl.am.wroc.pl
authors.forename: Maria
authors.initials: M
authors.lastname: Szcześniak
authors.forename: Janusz
authors.initials: J
authors.lastname: Pluta
mesh_terms: D000180:Acrylic Resins; D002626:Chemistry, Pharmaceutical; D004337:Drug Carriers / Q000737:chemistry*; D005782:Gels / Q000737:chemistry*; D006207:Half-Life; D006854:Hydrocortisone / Q000737:chemistry*; D057927:Hydrophobic and Hydrophilic Interactions; D011145:Polyvinyls / Q000737:chemistry*
chemical_list: D000180:Acrylic Resins; D004337:Drug Carriers; D005782:Gels; D011145:Polyvinyls; C006912:carboxypolymethylene; D006854:Hydrocortisone