title: Different clinical manifestation of cow's milk allergy in two preterm twins newborns.
abstract: Adverse reactions to cow's milk in the first year of life occur in 2-7%. There is an increase in the incidence of cow's milk protein allergy (CMA) in newborn population including premature infants. We report two cases of CMA in preterm twins. The first one developed recurrent episodes of proctocolitis and the second one two necrotizing enterocolitis (NEC) -like episodes. Our cases demonstrate different clinical presentations of the same disease and add to literature the peculiarity of the early onset, the recurrence of episodes of enterocolitis associated with increasing systemic eosinophilia and episodes clinically and radiologically mimicking NEC.
authors.affiliation: Department of Pediatrics, Obstetrics and Reproductive Medicine, Neonatal Pediatrics Section, University Hospital of Siena, Italy.
authors.forename: Caterina
authors.initials: C
authors.lastname: Coviello
authors.forename: Dhyana Chiara
authors.initials: DC
authors.lastname: Rodriquez
authors.forename: Sara
authors.initials: S
authors.lastname: Cecchi
authors.forename: Maria Luisa
authors.initials: ML
authors.lastname: Tataranno
authors.forename: Laura
authors.initials: L
authors.lastname: Farmeschi
authors.forename: Annalisa
authors.initials: A
authors.lastname: Mori
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Buonocore
mesh_terms: D000818:Animals; D004760:Enterocolitis / Q000276:immunology; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000175:diagnosis*; D008892:Milk / Q000009:adverse effects*; D016269:Milk Hypersensitivity / Q000175:diagnosis*; D011247:Pregnancy; D011350:Proctocolitis / Q000276:immunology; D014427:Twins