title: Degradation of Malachite green by Potassium persulphate, its enhancement by 1,8-dimethyl-1,3,6,8,10,13-hexaazacyclotetradecane nickel(II) perchlorate complex, and removal of antibacterial activity.
abstract: In this study, degradation of Malachite green (MG) (10mg/L) by Potassium persulphate (KPS) (1 g/L), and KPS in presence of (1,8-dimethyl-1,3,6,8,10,13-hexaazacyclotetradecane) nickel(II) perchlorate (complex1), (200 μM), was investigated by spectrophotometric and HPLC methods. KPS alone had ability to degrade MG. Interestingly, rate of degradation of MG was enhanced upon addition of complex1. Degradation was effective at pH range of 3-9 and was found to be dependent on initial concentration of KPS, complex1, MG, and pH. Degradation of MG by KPS was not significantly affected in presence of Ni(II) ions whereas in presence of Fe(II) ions degradation was incomplete. Ability of KPS to reduce TOC increased in presence of complex1. Transformation products were analysed by LC-ESI-MS. Finally, treatment of MG with complex1 and KPS resulted in removal of antibacterial activity of MG under in vitro conditions.
authors.affiliation: Department of Chemistry, Birla Institute of Technology and Science, Pilani, K.K. Birla Goa Campus, NH17B, Zuarinagar, Goa 403 726, India.
authors.forename: Subramanian
authors.initials: S
authors.lastname: Gokulakrishnan
authors.forename: Priyadarshini
authors.initials: P
authors.lastname: Parakh
authors.forename: Halan
authors.initials: H
authors.lastname: Prakash
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002244:Carbon / Q000032:analysis; D002384:Catalysis; D002851:Chromatography, High Pressure Liquid; D004396:Coloring Agents; D056831:Coordination Complexes / Q000737:chemistry*; D004926:Escherichia coli / Q000187:drug effects; D006863:Hydrogen-Ion Concentration; D007202:Indicators and Reagents; D007501:Iron / Q000737:chemistry; D007700:Kinetics; D008670:Metals / Q000378:metabolism; D008826:Microbial Sensitivity Tests; D009532:Nickel / Q000737:chemistry; D010084:Oxidation-Reduction; D017680:Potassium Compounds / Q000737:chemistry*; D012394:Rosaniline Dyes / Q000737:chemistry*; D021241:Spectrometry, Mass, Electrospray Ionization; D013431:Sulfates / Q000737:chemistry*
chemical_list: C573701:(1,8-dimethyl-1,3,6,8,10,13-hexaazacyclotetradecane)nickel(II); D000900:Anti-Bacterial Agents; D004396:Coloring Agents; D056831:Coordination Complexes; D007202:Indicators and Reagents; D008670:Metals; D017680:Potassium Compounds; D012394:Rosaniline Dyes; D013431:Sulfates; C005095:malachite green; C009007:potassium persulfate; D002244:Carbon; D009532:Nickel; D007501:Iron