title: [Management of acute ischemic stroke].
abstract: The management of acute ischemic stroke aims to verify the clinical diagnosis, to start general supportive care and to enable decision-making about specific forms of therapy.The risk-benefit ratio is time-dependent for many therapeutic options; therefore time delays are a disadvantage within the rescue chain. The trained and multidisciplinary team of the stroke unit forms the backbone of acute management. In addition, technical infrastructure influences therapeutic options and cerebral imaging is the cornerstone.The following four therapies are evidence-based: treatment on a stroke unit, thrombolysis, early administration of acetylsalicylic acid (ASS) and hemicraniectomy in patients younger than 60 years with a so-called malignant infarction.This article describes the necessary diagnostic steps and the general and specific therapeutic options that comprise acute management within the first 48 h.
authors.affiliation: Klinik für Neurologie, Charité - Universitätsmedizin Berlin, Charitéplatz 1, Berlin, Germany. christian.nolte@charite.de
authors.forename: C H
authors.initials: CH
authors.lastname: Nolte
authors.forename: M
authors.initials: M
authors.lastname: Endres
mesh_terms: D001241:Aspirin / Q000008:administration & dosage*; D002545:Brain Ischemia / Q000150:complications* / Q000175:diagnosis / Q000628:therapy*; D056424:Decompressive Craniectomy / Q000379:methods*; D006801:Humans; D020521:Stroke / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy*; D015912:Thrombolytic Therapy / Q000379:methods*
chemical_list: D001241:Aspirin