title: Quality of life after radiosurgery for cerebral arteriovenous malformation patients who present with seizure.
abstract: OBJECTIVE
  This study assessed the quality of life (QOL) and employment status after radiosurgery for arteriovenous malformation (AVM) patients who presented with seizure.
  
  
  METHODS
  Between 1997 and 2006, 78 AVM patients who presented with seizure and received radiosurgery were assessed using serial imaging tests, clinical evaluations that included employment status, and a QOL survey. The QOL questionnaire was developed as a retrospective screening tool to estimate the present QOL and the patient's self-rated relative changes (trend values) in QOL after radiosurgery. These results were correlated to one another using the Engel seizure frequency scoring system.
  
  
  RESULTS
  The follow-up periods ranged from 48.0 to 151.0 months (mean, 92.5). The mean trend values and mean QOL scores in patients with seizure freedom or AVM obliteration were significantly greater than in patients without these outcomes (all P values < 0.05). Good radiosurgical outcomes were associated with attaining employment (all P values < 0.05). However, differences in employment status were not significant (P = 0.186) despite a higher proportion of patients who described their workplace activity as improved compared with their pre-radiosurgical activity at the last follow-up evaluation.
  
  
  CONCLUSIONS
  Radiosurgery may improve QOL and employment status in AVM patients, especially patients who experience seizure freedom or AVM obliteration.
authors.affiliation: Department of Neurosurgery, Dongguk University Graduate School, Seoul            Department of Neurosurgery, Seoul National University College of Medicine, Seoul, Korea.
authors.forename: S-Y
authors.initials: SY
authors.lastname: Yang
authors.forename: S H
authors.initials: SH
authors.lastname: Paek
authors.forename: D G
authors.initials: DG
authors.lastname: Kim
authors.forename: H-T
authors.initials: HT
authors.lastname: Chung
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D002538:Intracranial Arteriovenous Malformations / Q000175:diagnosis / Q000453:epidemiology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D011788:Quality of Life / Q000523:psychology; D016634:Radiosurgery / Q000523:psychology; D012640:Seizures / Q000175:diagnosis / Q000453:epidemiology / Q000601:surgery*; D011795:Surveys and Questionnaires; D016896:Treatment Outcome; D055815:Young Adult