title: Should idiopathic facial aseptic granuloma be considered granulomatous rosacea? Report of three pediatric cases.
abstract: Idiopathic facial aseptic granuloma (IFAG), or pyodermite froide du visage, is a skin disease reported only in children and characterized by painless red nodules usually located on the cheeks. Its etiology is still unclear, but some authors considered the possibility that IFAG might be included in the spectrum of granulomatous rosacea (GR). The histopathological features of IFAG and GR are quite similar, showing perifolliculitis, granulomas, folliculitis, and lymphocytes and plasmacells around epithelioid histiocytes. In the present article, we discuss three cases in which an association between a facial nodule, compatible with both IFAG and GR, and recurrent chalazia make us support the hypothesis that IFAG should be considered as GR.
authors.affiliation: Dermatology Clinic, Department of Internal Medicine, Aging and Nephrological Diseases, University of Bologna, Bologna, Italy.
authors.forename: Iria
authors.initials: I
authors.lastname: Neri
authors.forename: Beatrice
authors.initials: B
authors.lastname: Raone
authors.forename: Arianna
authors.initials: A
authors.lastname: Dondi
authors.forename: Cosimo
authors.initials: C
authors.lastname: Misciali
authors.forename: Annalisa
authors.initials: A
authors.lastname: Patrizi
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001707:Biopsy, Needle; D002675:Child, Preschool; D003879:Dermatologic Agents / Q000627:therapeutic use; D003937:Diagnosis, Differential; D004359:Drug Therapy, Combination; D005148:Facial Dermatoses / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology; D005260:Female; D006099:Granuloma / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D007223:Infant; D008297:Male; D018570:Risk Assessment; D012393:Rosacea / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology*; D012494:Sampling Studies
chemical_list: D000900:Anti-Bacterial Agents; D003879:Dermatologic Agents