title: [Monomers containing 2'-o-alkoxymethyl groups as synthons for the synthesis of oligoribonucleotides by the phosphotriester method].
abstract: A general scheme for the synthesis of ribonucleotide monomers containing alkoxymethyl group in 2'-O-position for the solid-phase phosphotriester oligonucleotide synthesis using O-nucleophilic intramolecular catalysis has been developed. In particular, the monomers containing 2'-O-modifying 2-azidoethoxymethyl, propargyloxymethyl, or 3,4-cyclocarbonatebutoxymethyl groups has been prepared.
authors.forename: A V
authors.initials: AV
authors.lastname: Aralov
authors.forename: V N
authors.initials: VN
authors.lastname: Klykov
authors.forename: O G
authors.initials: OG
authors.lastname: Chakhmakhcheva
authors.forename: V A
authors.initials: VA
authors.lastname: Efimov
mesh_terms: D000447:Aldehydes / Q000737:chemistry; D000480:Alkynes / Q000737:chemistry; D001386:Azides / Q000737:chemistry; D002384:Catalysis; D015394:Molecular Structure; D009843:Oligoribonucleotides / Q000138:chemical synthesis*; D012265:Ribonucleotides / Q000737:chemistry*; D060327:Solid-Phase Synthesis Techniques
chemical_list: D000447:Aldehydes; D000480:Alkynes; D001386:Azides; D009843:Oligoribonucleotides; D012265:Ribonucleotides