title: Enhanced shape-selective recognition of anion guests through complexation-induced organization of porphyrin hosts.
abstract: We present a fortuitous discovery of enhanced shape-selective recognition of anion guests that stems from a complexation-induced conformational change in porphyrin hosts upon anion binding. Porphyrin hosts reported here exist in a conformation that is not favorable to guest binding. Anions that bind strongly are those that can induce a conformational change in the host to allow guest binding. Furthermore, guests that mimic the shape of the newly formed pocket bind the strongest.
authors.affiliation: Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces, New Mexico 88003, United States.
authors.forename: MariJo
authors.initials: M
authors.lastname: Wienkers
authors.forename: Josmalen
authors.initials: J
authors.lastname: Ramos
authors.forename: Hikma
authors.initials: H
authors.lastname: Jemal
authors.forename: Chaz
authors.initials: C
authors.lastname: Cardenas
authors.forename: Paul
authors.initials: P
authors.lastname: Wiget
authors.forename: Alfreda
authors.initials: A
authors.lastname: Nelson
authors.forename: Shiloh
authors.initials: S
authors.lastname: Free
authors.forename: Jun
authors.initials: J
authors.lastname: Wu
authors.forename: Rebecca
authors.initials: R
authors.lastname: Roach
authors.forename: Marius
authors.initials: M
authors.lastname: Vulcan
authors.forename: Kristopher
authors.initials: K
authors.lastname: Waynant
authors.forename: Kyle
authors.initials: K
authors.lastname: Fort
authors.forename: Anna
authors.initials: A
authors.lastname: Vladimirova
authors.forename: Jeffery
authors.initials: J
authors.lastname: Sun
authors.forename: Samuel Eli
authors.initials: SE
authors.lastname: Hunt
authors.forename: Dmitry M
authors.initials: DM
authors.lastname: Rudkevich
authors.forename: Stephen D
authors.initials: SD
authors.lastname: Starnes
mesh_terms: D000838:Anions; D008958:Models, Molecular; D008968:Molecular Conformation; D015394:Molecular Structure; D011166:Porphyrins / Q000737:chemistry*
chemical_list: D000838:Anions; D011166:Porphyrins