title: High-penetration swept source Doppler optical coherence angiography by fully numerical phase stabilization.
abstract: A high-penetration swept-source optical coherence tomography (HP-SS-OCT) system based on a 1-μm short cavity laser is developed. Doppler OCT processing is applied, along with a custom-made numerical phase stabilization algorithm; this process does not require additional calibration hardware. Thus, our phase stabilization method is simple and can be employed in a variety of SS-OCT systems. The bidirectional blood flow and vasculature in the deep choroid was successfully imaged via two Doppler modes that use different time intervals for Doppler processing. En face projection image of squared power of Doppler shift is compared to ICGA, and the utility of our method is verified.
authors.affiliation: Computational Optics Group, University of Tsukuba, Tsukuba, Ibaraki, Japan.
authors.forename: Young-Joo
authors.initials: YJ
authors.lastname: Hong
authors.forename: Shuichi
authors.initials: S
authors.lastname: Makita
authors.forename: Franck
authors.initials: F
authors.lastname: Jaillon
authors.forename: Myeong Jin
authors.initials: MJ
authors.lastname: Ju
authors.forename: Eun Jung
authors.initials: EJ
authors.lastname: Min
authors.forename: Byeong Ha
authors.initials: BH
authors.lastname: Lee
authors.forename: Masahide
authors.initials: M
authors.lastname: Itoh
authors.forename: Masahiro
authors.initials: M
authors.lastname: Miura
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Yasuno
mesh_terms: D000792:Angiography / Q000295:instrumentation*; D001783:Blood Flow Velocity; D002829:Choroid / Q000098:blood supply* / Q000502:physiology*; D017076:Computer-Aided Design; D004867:Equipment Design; D019544:Equipment Failure Analysis; D006801:Humans; D007089:Image Enhancement / Q000295:instrumentation*; D017078:Laser-Doppler Flowmetry / Q000295:instrumentation*; D041623:Tomography, Optical Coherence / Q000295:instrumentation*