title: [Molecular genetics advances of congenital idiopathic nystagmus].
abstract: Congenital idiopathic nystagmus (CIN) is genetically heterogeneous. Autosomal dominant, autosomal recessive and X-linked patterns of inheritance have described. At least three distinct loci are related to autosomal dominant and X-linked patterns. One causative gene for X-linked form has been identified (FRMD7, Xq26.2) through linkage analysis. The molecular genetics advances of the congenital idiopathic nystagmus (CIN) are reviewed.
authors.affiliation: Clinical College of Ophthalmology of Tianjin Medical University, Tianjin Eye Hospital and Institute, Tianjin Key Laboratory of Ophthalmology and Visual Science, Tianjin 300020, China.
authors.forename: Xiao-juan
authors.initials: XJ
authors.lastname: Wang
authors.forename: Kan-xing
authors.initials: KX
authors.lastname: Zhao
mesh_terms: D003598:Cytoskeletal Proteins / Q000235:genetics*; D006801:Humans; D008565:Membrane Proteins / Q000235:genetics*; D020417:Nystagmus, Congenital / Q000235:genetics*
chemical_list: D003598:Cytoskeletal Proteins; D008565:Membrane Proteins