title: [Adaptive immune response of people living near chemically hazardous object].
abstract: The article presents data dynamics of adaptive immune responses of people for a long time living in adverse environmental conditions caused by pollution of the environment by industrial toxic waste. It is shown that in the process of adaptation to adverse environmental factors, changes in the immune system are in the phase fluctuations of immunological parameters that are accompanied by changes in the structure of immunodependent pathology. Most sensitive to prolonged exposure to toxic compounds are the cellular mechanisms of immune protection. Violations of the structural and quantitative and functional parameters of the link of the immune system are leading to the formation of immunopathological processes.
authors.forename: S V
authors.initials: SV
authors.lastname: Petlenko
authors.forename: M B
authors.initials: MB
authors.lastname: Ivanov
authors.forename: Iu B
authors.initials: IuB
authors.lastname: Goverdovskiĭ
authors.forename: E G
authors.initials: EG
authors.lastname: Bogdanova
authors.forename: A V
authors.initials: AV
authors.lastname: Golubkov
mesh_terms: D004781:Environmental Exposure / Q000009:adverse effects*; D005260:Female; D015386:Hazardous Substances / Q000009:adverse effects*; D006801:Humans; D007111:Immunity, Cellular / Q000187:drug effects*; D008297:Male; D012426:Russia; D013997:Time Factors
chemical_list: D015386:Hazardous Substances