title: Posterior urethral complications of the treatment of prostate cancer.
abstract: • To review the less common and not widely discussed, but much more serious complications of prostate cancer treatment of: urethral stricture, bladder neck contracture and urorectal fistula. • The treatment options for patients with organ-confirmed prostate cancer include: radical prostatectomy (RP), brachytherapy (BT), external beam radiotherapy (EBRT), high-intensity focussed ultrasound (HIFU) and cryotherapy; with each method or combination of methods having associated complications. • Complications resulting from RP are relatively easy to manage, with rapid recovery and return to normal activities, and usually a return to normal bodily functions. • However, after non-surgical treatments, i.e. BT, EBRT, HIFU and cryotherapy, these same problems are more difficult to treat with a much slower return to a much lower level of function. • When counselling patients about the primary treatment of prostate cancer they should be advised that although the same type of complication may occur after surgical or non-surgical treatment, the scope and scale of that complication, the ease with which it is treated and the degree of restoration of normality after treatment, is altogether in favour of surgery in those for whom surgery is appropriate and who are fit for surgery.
authors.affiliation: Institute of Urology, London, UK. kelly.higgs@ucl.ac.uk
authors.forename: Anthony R
authors.initials: AR
authors.lastname: Mundy
authors.forename: Daniela E
authors.initials: DE
authors.lastname: Andrich
mesh_terms: D001918:Brachytherapy / Q000009:adverse effects; D003286:Contracture / Q000209:etiology*; D017679:Cryotherapy / Q000009:adverse effects; D057086:High-Intensity Focused Ultrasound Ablation / Q000009:adverse effects; D006801:Humans; D008297:Male; D011468:Prostatectomy; D011471:Prostatic Neoplasms / Q000628:therapy*; D011878:Radiotherapy / Q000009:adverse effects; D012003:Rectal Fistula / Q000209:etiology*; D016879:Salvage Therapy / Q000379:methods; D014522:Urethral Diseases / Q000209:etiology*; D014525:Urethral Stricture / Q000209:etiology; D001745:Urinary Bladder Diseases / Q000209:etiology*; D014548:Urinary Fistula / Q000209:etiology*