title: Absorption-mode: the next generation of Fourier transform mass spectra.
abstract: The Fourier transform spectrum can be presented in the absorption-mode (commonly used in FT-NMR), magnitude-mode (FT-ICR), and power-mode (engineering applications). As is routinely used in FT-NMR, it is well-known that the absorption-mode display gives a much narrower peak shape which greatly improves the spectrum; recently, the successful solution of the phase equation allowed broadband phase correction which makes it possible to apply the absorption-mode routinely in FT-ICR. With the empirical evidence provided herein, it has been confirmed that in addition to the improvement on resolving power, compared to the conventional magnitude-mode, the new absorption-mode improves the signal-to-noise ratio (S/N) of a spectrum by 1.4-fold and can improve the mass accuracy up to 2-fold with no extra cost in instrumentation. Therefore, it is worthwhile to apply and promote absorption-mode in routine FT-ICR experiments.
authors.affiliation: Department of Chemistry, University of Warwick, Coventry, United Kingdom.
authors.forename: Yulin
authors.initials: Y
authors.lastname: Qi
authors.forename: Mark P
authors.initials: MP
authors.lastname: Barrow
authors.forename: Huilin
authors.initials: H
authors.lastname: Li
authors.forename: Joseph E
authors.initials: JE
authors.lastname: Meier
authors.forename: Steve L
authors.initials: SL
authors.lastname: Van Orden
authors.forename: Christopher J
authors.initials: CJ
authors.lastname: Thompson
authors.forename: Peter B
authors.initials: PB
authors.lastname: O'Connor