title: Rat models of pancreatitis pain.
abstract: Pancreatic pain is often severe and difficult to treat clinically. Many animal models that mimic pancreatic pain are typically short term and invasive in nature. The present chapter describes the development and characterization of two non-invasive rat models of pancreatitis, one acute and one chronic. The two models described here are simple to replicate, giving them advantage over other animal models of pancreatic inflammation. A goal of this chapter is also to detail their usefulness as visceral pain models.
authors.affiliation: Department of Physiology, Chandler Medical Center, University of Kentucky, Lexington, KY, USA. Karin.High@uky.edu
authors.forename: Karin N
authors.initials: KN
authors.lastname: Westlund
authors.forename: Louis
authors.initials: L
authors.lastname: Vera-Portocarrero
mesh_terms: D000208:Acute Disease; D000818:Animals; D004195:Disease Models, Animal; D008297:Male; D010195:Pancreatitis / Q000503:physiopathology* / Q000628:therapy; D050500:Pancreatitis, Chronic / Q000503:physiopathology / Q000628:therapy; D051381:Rats; D011917:Rats, Inbred Lew; D017207:Rats, Sprague-Dawley; D059265:Visceral Pain