title: Erythropoietin processing in erythropoietic system and central nervous system.
abstract: We describe possible functions of carbohydrates attached to growth factors and strategies to examine the functions, concentrating on erythropoietin, a major regulator of erythropoiesis. Erythropoietin in erythropoiesis functions as an endocrine hormone; it is produced by kidney cells and transferred into the circulation to hemopoietic sites. In the brain, erythropoietin acts on neurons in a paracrine fashion. Comparison of glycosylation has been made between kidney and brain erythropoietins.
authors.affiliation: Department of Food Science and Technology, Faculty of Agriculture, Kyoto University, 606, Kyoto, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Nagao
authors.forename: S
authors.initials: S
authors.lastname: Masuda
authors.forename: M
authors.initials: M
authors.lastname: Ueda
authors.forename: R
authors.initials: R
authors.lastname: Sasaki