title: Neaumycin: a new macrolide from Streptomyces sp. NEAU-x211.
abstract: Neaumycin, a new 30-membered macrolide featuring an internal diester bridge, a molecular architecture that is unprecedented among known macrolide natural products, was isolated from a soil actinomycete strain Streptomyces sp. NEAU-x211. The structure of neaumycin was elucidated on the basis of comprehensive mass and NMR spectroscopic interpretation, including the relative stereochemistry of four independent coupling systems.
authors.affiliation: Department of Chemistry, The Scripps Research Institute, Jupiter, Florida 33458, USA.
authors.forename: Sheng-Xiong
authors.initials: SX
authors.lastname: Huang
authors.forename: Xiang-Jing
authors.initials: XJ
authors.lastname: Wang
authors.forename: Yijun
authors.initials: Y
authors.lastname: Yan
authors.forename: Ji-Dong
authors.initials: JD
authors.lastname: Wang
authors.forename: Ji
authors.initials: J
authors.lastname: Zhang
authors.forename: Chong-Xi
authors.initials: CX
authors.lastname: Liu
authors.forename: Wen-Sheng
authors.initials: WS
authors.lastname: Xiang
authors.forename: Ben
authors.initials: B
authors.lastname: Shen
mesh_terms: D018942:Macrolides / Q000737:chemistry* / Q000302:isolation & purification; D015394:Molecular Structure; D013237:Stereoisomerism; D013302:Streptomyces / Q000737:chemistry*
chemical_list: D018942:Macrolides; C572275:neaumycin