title: Epstein-Barr Virus (EBV)-Associated Haemophagocytic Syndrome.
abstract: We describe the case of a 17- year old female who developed fatal haemophagocytic syndrome (HPS) one month following acute infection caused by Epstein-Barr virus (EBV). Despite initiation of treatment and reduction of EBV load, laboratory signs of HPS as severe cytopenia, hypofibrinogenemia, hyperferritinemia and hypertriglyceridemia persisted, and the patient died of multiorgan failure. HPS is a rare, but life-threatening complication of EBV infection.
authors.affiliation: Department of Hematology, Catholic University, Rome, Italy.
authors.forename: Lorenza
authors.initials: L
authors.lastname: Torti
authors.forename: Luigi M
authors.initials: LM
authors.lastname: Larocca
authors.forename: Giuseppina
authors.initials: G
authors.lastname: Massini
authors.forename: Annarosa
authors.initials: A
authors.lastname: Cuccaro
authors.forename: Elena
authors.initials: E
authors.lastname: Maiolo
authors.forename: Rosaria
authors.initials: R
authors.lastname: Santangelo
authors.forename: Maria
authors.initials: M
authors.lastname: Bianchi
authors.forename: Mariano Alberto
authors.initials: MA
authors.lastname: Pennisi
authors.forename: Stefan
authors.initials: S
authors.lastname: Hohaus
authors.forename: Luciana
authors.initials: L
authors.lastname: Teofili