title: Autologous conjunctival epithelium transplantation and scleral patch graft for postlensectomy wound leakage in Marfan syndrome.
abstract: OBJECTIVE
  We report a case of woman with Marfan syndrome and longstanding postlensectomy scleral wound dehiscence.
  
  
  METHODS
  A 34-year-old woman with Marfan syndrome who underwent lensectomy 20 years ago had conjunctival leakage with chronic hypotony and conjunctival cystic degeneration secondary to scleral wound dehiscence. Presentation, clinical evaluation, and particular treatment with autologous cultivated conjunctival epithelium transplantation and scleral patch graft are described.
  
  
  RESULTS
  A 6-month follow-up confirmed complete epithelization of the ocular surface and absence of leaking from the wound with normal intraocular pressure.
  
  
  CONCLUSIONS
  Transplantation of autologous cultivated conjunctival epithelium appears to be a valid strategy in the treatment of ocular disease requiring extensive excision of the conjunctiva.
authors.affiliation: Ophthalmology Unit, Department of Biopathology, University of Rome Tor Vergata, Rome, Italy.
authors.forename: Raffaele
authors.initials: R
authors.lastname: Mancino
authors.forename: Francesco
authors.initials: F
authors.lastname: Aiello
authors.forename: Simona
authors.initials: S
authors.lastname: Ceccarelli
authors.forename: Cinzia
authors.initials: C
authors.lastname: Marchese
authors.forename: Chiara
authors.initials: C
authors.lastname: Varesi
authors.forename: Carlo
authors.initials: C
authors.lastname: Nucci
authors.forename: Luciano
authors.initials: L
authors.lastname: Cerulli
mesh_terms: D000328:Adult; D017690:Cell Transplantation; D002478:Cells, Cultured; D003228:Conjunctiva / Q000166:cytology*; D004479:Ectopia Lentis / Q000601:surgery*; D004848:Epithelium / Q000637:transplantation*; D005260:Female; D006801:Humans; D007908:Lens, Crystalline / Q000601:surgery; D008382:Marfan Syndrome / Q000150:complications*; D011183:Postoperative Complications; D012590:Sclera / Q000637:transplantation*; D013529:Surgical Wound Dehiscence / Q000209:etiology / Q000601:surgery*; D014182:Transplantation, Autologous; D014792:Visual Acuity / Q000502:physiology; D014945:Wound Healing / Q000502:physiology