title: Induction of pH sensitivity on the fluorescence lifetime of quantum dots by NIR fluorescent dyes.
abstract: Modulation of the fluorescence lifetime (FLT) of CdTeSe/ZnS quantum dots (QDs) by near-IR (NIR) organic chromophores represents a new strategy for generating reproducible pH-sensing nanomaterials. The hybrid construct transfers the pH sensitivity of photolabile NIR cyanine dyes to highly emissive and long-lifetime pH-insensitive QDs, thereby inducing a reproducible FLT change from 29 ns at pH >7 to 12 ns at pH <5. This approach provides an unparalleled large dynamic FLT range for pH sensing at NIR wavelengths.
authors.affiliation: Department of Radiology, Washington University, St. Louis, Missouri 63110, United States.
authors.forename: Rui
authors.initials: R
authors.lastname: Tang
authors.forename: Hyeran
authors.initials: H
authors.lastname: Lee
authors.forename: Samuel
authors.initials: S
authors.lastname: Achilefu
mesh_terms: D005453:Fluorescence; D031541:Fluorescence Resonance Energy Transfer; D005456:Fluorescent Dyes / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D046529:Microscopy, Electron, Transmission; D045663:Quantum Dots; D013056:Spectrophotometry, Ultraviolet; D019265:Spectroscopy, Near-Infrared / Q000379:methods*
chemical_list: D005456:Fluorescent Dyes