title: Application of optical imaging and spectroscopy to radiation biology.
abstract: Optical imaging and spectroscopy is a diverse field that has been of critical importance in a wide range of areas in radiation research. It is capable of spanning a wide range of spatial and temporal scales, and has the sensitivity and specificity needed for molecular and functional imaging. This review will describe the basic principles of optical imaging and spectroscopy, highlighting a few relevant applications to radiation research.
authors.affiliation: Department of Radiation Oncology, Duke University Medical Center, Durham, North Carolina, USA. greg.palmer@duke.edu
authors.forename: Gregory M
authors.initials: GM
authors.lastname: Palmer
authors.forename: Karthik
authors.initials: K
authors.lastname: Vishwanath
authors.forename: Mark W
authors.initials: MW
authors.lastname: Dewhirst
mesh_terms: D000818:Animals; D015687:Cell Hypoxia; D058948:Cell Tracking / Q000379:methods; D005336:Fiber Optic Technology / Q000379:methods; D005470:Fluorometry / Q000379:methods; D017930:Genes, Reporter; D006801:Humans; D008163:Luminescent Measurements / Q000379:methods; D008164:Luminescent Proteins / Q000032:analysis; D008853:Microscopy / Q000379:methods; D057054:Molecular Imaging / Q000379:methods*; D009369:Neoplasms / Q000737:chemistry / Q000473:pathology / Q000532:radiotherapy; D009374:Neoplasms, Experimental / Q000737:chemistry / Q000473:pathology; D055620:Optical Phenomena; D010108:Oxyhemoglobins / Q000032:analysis; D061088:Photoacoustic Techniques; D011853:Radiobiology / Q000379:methods*; D012542:Scattering, Radiation; D013057:Spectrum Analysis / Q000379:methods*; D014054:Tomography / Q000379:methods; D041623:Tomography, Optical Coherence / Q000379:methods
chemical_list: D008164:Luminescent Proteins; D010108:Oxyhemoglobins