title: Electrochemical nanomaterial-based nucleic acid aptasensors.
abstract: Recent progress in the development of electrochemical nanomaterial-aptamer-based biosensors is summarized. Aptamers are nucleic acid ligands that can be generated against amino acids, drugs, proteins, and other molecules. They are isolated from a large random library of synthetic nucleic acids by an iterative process of binding, separation, and amplification, called systematic evolution of ligands by exponential enrichment (SELEX). In this review, different methods of integrating aptamers with different nanomaterials and nanoparticles for electrochemical biosensing application are described.
authors.affiliation: Dipartimento di Chimica, Università degli Studi di Firenze, 50121 Firenze, Italy. ilaria.palchetti@unifi.it
authors.forename: Ilaria
authors.initials: I
authors.lastname: Palchetti
authors.forename: Marco
authors.initials: M
authors.lastname: Mascini
mesh_terms: D000818:Animals; D052157:Aptamers, Nucleotide / Q000737:chemistry* / Q000235:genetics; D015374:Biosensing Techniques / Q000295:instrumentation* / Q000379:methods; D055664:Electrochemical Techniques / Q000295:instrumentation* / Q000379:methods; D006801:Humans; D049329:Nanostructures / Q000737:chemistry*; D052156:SELEX Aptamer Technique / Q000295:instrumentation* / Q000379:methods
chemical_list: D052157:Aptamers, Nucleotide