title: Effect of orange peel essential oil on oxidative stress in AOM animals.
abstract: The processing parameters of pump speed, inlet air temperature, outlet air temperature and homogenization pressure were evaluated. Encapsulation efficiency is high with a satisfied releasing rate. Then, acute otitis media (AOM) animal model was built and diet containing orange peel essential oil microcapsules were administrated to AOM animals. Pharmacological test showed that orange peel essential oil treatment could decrease serum and cochlea malondialdehyde (MDA), immunoglobulins A (IgA), immunoglobulins G (IgG), immunoglobulins M (IgM) levels and increase antioxidant enzymes activities. It can be concluded that orange peel essential oil treatment could decrease oxidative injury in acute otitis media rats.
authors.affiliation: Otolaryngology Head & Neck Department of Xiangya Hospital, Central South University, Changsha 410008, Hunan, PR China.
authors.forename: Yun-Xia
authors.initials: YX
authors.lastname: Lv
authors.forename: Su-Ping
authors.initials: SP
authors.lastname: Zhao
authors.forename: Jun-Yi
authors.initials: JY
authors.lastname: Zhang
authors.forename: Hua
authors.initials: H
authors.lastname: Zhang
authors.forename: Zhi-Hai
authors.initials: ZH
authors.lastname: Xie
authors.forename: Geng-Ming
authors.initials: GM
authors.lastname: Cai
authors.forename: Wei-Hong
authors.initials: WH
authors.lastname: Jiang
mesh_terms: D000208:Acute Disease; D000818:Animals; D002214:Capsules; D032084:Citrus sinensis / Q000737:chemistry*; D005978:Glutathione / Q000378:metabolism; D007136:Immunoglobulins / Q000378:metabolism; D008297:Male; D008315:Malondialdehyde / Q000378:metabolism; D009822:Oils, Volatile / Q000494:pharmacology*; D010033:Otitis Media / Q000276:immunology / Q000378:metabolism*; D018384:Oxidative Stress / Q000187:drug effects*; D019441:Plant Epidermis / Q000737:chemistry; D051381:Rats; D017207:Rats, Sprague-Dawley
chemical_list: D002214:Capsules; D007136:Immunoglobulins; D009822:Oils, Volatile; D008315:Malondialdehyde; D005978:Glutathione