title: [Monitoring of organ functions. Dysfunction of kidneys, liver, gastrointestinal tract, and coagulation].
abstract: Monitoring of organ function is one of the core tasks of intensive care medicine. Although various monitoring devices and parameters have already been established for some organs, there are no or only few conditionally useful parameters or scores available for the kidneys, liver, gastrointestinal tract, and blood coagulation. Therefore, specific biomarkers and scores as well as combinations of both are currently investigated for better monitoring of these organs. This article gives a critical overview of currently used as well as investigational biomarkers, tests and scores in general, and shows some examples of the implications for common diseases, clinical situations and constellations in the intensive care unit.
authors.affiliation: Universitätsklinik für Innere Medizin I, Medizinische Intensivstation, Medizinische Universität Innsbruck, Anichstr. 35, 6020, Innsbruck, Österreich.
authors.forename: G F
authors.initials: GF
authors.lastname: Lehner
authors.forename: C
authors.initials: C
authors.lastname: Pechlaner
authors.forename: I W
authors.initials: IW
authors.lastname: Graziadei
authors.forename: M
authors.initials: M
authors.lastname: Joannidis
mesh_terms: D058186:Acute Kidney Injury / Q000175:diagnosis / Q000401:mortality; D015415:Biomarkers / Q000097:blood; D001778:Blood Coagulation Disorders / Q000175:diagnosis; D001780:Blood Coagulation Tests; D042241:Early Diagnosis; D005767:Gastrointestinal Diseases / Q000175:diagnosis / Q000401:mortality; D017052:Hospital Mortality; D006801:Humans; D007362:Intensive Care Units; D017093:Liver Failure / Q000175:diagnosis / Q000401:mortality; D008111:Liver Function Tests; D008991:Monitoring, Physiologic / Q000379:methods*; D009102:Multiple Organ Failure / Q000175:diagnosis* / Q000401:mortality; D010182:Pancreatic Diseases / Q000175:diagnosis / Q000401:mortality; D010186:Pancreatic Function Tests; D019283:Pancreatitis, Acute Necrotizing / Q000175:diagnosis / Q000401:mortality; D011379:Prognosis; D012016:Reference Values; D012307:Risk Factors; D012720:Severity of Illness Index
chemical_list: D015415:Biomarkers