title: [Ultrastructure of coronary microvessels in conditions of heart reperfusion following prolonged ischemia while applying various methods of artificial hypothermia].
abstract: It has been found out that in children with Roger's disease corrected in the conditions of two fundamentally different procedures of anesthetic management, myocardial reperfusion after cardiac arrest under artificial hypothermic circulation is accompanied by obstruction of more than 30% of coronary bed microvessels with hydropic endothelial cells or their cystiform fragments. The content of necrotic cells increases, while the "working" cells demonstrate a decrease in myocropinocytotic transport characteristics. Circulatory arrest under perfusionless hypothermia and immersion reperfusion do not result in a dramatic change of general morphology of microvessels as compared to the control group, while a heterogenic response of the structures responsible for transendothelial transfer of macromolecules provides the basis for recovery of the endothelium structure and function, as a patient's temperature reaches a standard value.
authors.forename: G M
authors.initials: GM
authors.lastname: Kazanskaia
authors.forename: A M
authors.initials: AM
authors.lastname: Volkov
authors.forename: T M
authors.initials: TM
authors.lastname: D'iakonitsa
authors.forename: A M
authors.initials: AM
authors.lastname: Karas'kova
mesh_terms: D000749:Anemia, Megaloblastic / Q000473:pathology / Q000601:surgery; D002675:Child, Preschool; D050792:Circulatory Arrest, Deep Hypothermia Induced; D003326:Coronary Circulation; D003920:Diabetes Mellitus / Q000473:pathology / Q000601:surgery; D004730:Endothelium, Vascular / Q000648:ultrastructure*; D005260:Female; D006319:Hearing Loss, Sensorineural / Q000473:pathology / Q000601:surgery; D006801:Humans; D007223:Infant; D007655:Ketoglutarate Dehydrogenase Complex / Q000172:deficiency; D008297:Male; D055806:Microvessels / Q000648:ultrastructure*; D015425:Myocardial Reperfusion; D009206:Myocardium / Q000648:ultrastructure*; D013832:Thiamine Deficiency / Q000151:congenital
chemical_list: D007655:Ketoglutarate Dehydrogenase Complex