title: Interfacial organic synthesis in a simple droplet-based microfluidic system.
abstract: A spherical liquid-liquid interface can be obtained by dispersing one liquid phase into another to form droplets, which will facilitate the two-phase reactions between the immiscible participating fluids. The phase transfer catalysts assembled at the droplet "wall" catalyze the reactions between the aqueous and organic phases. The study illustrates an interfacial synthetic approach which is ideal for the biphasic reaction by taking advantage of the droplet-based microdevice. The improved reaction efficiency can be attributed to the high surface-to-volume ratio and internal flow circulation in the droplets.
authors.affiliation: Department of Chemistry and Institutes of Biomedical Sciences, Fudan University, 220 Handan Road, Shanghai, 200433, China.
authors.forename: Ji
authors.initials: J
authors.lastname: Ji
authors.forename: Yiqing
authors.initials: Y
authors.lastname: Zhao
authors.forename: Liping
authors.initials: L
authors.lastname: Guo
authors.forename: Baohong
authors.initials: B
authors.lastname: Liu
authors.forename: Chang
authors.initials: C
authors.lastname: Ji
authors.forename: Pengyuan
authors.initials: P
authors.lastname: Yang
mesh_terms: D002384:Catalysis; D004987:Ethers / Q000138:chemical synthesis / Q000737:chemistry; D046210:Microfluidic Analytical Techniques / Q000295:instrumentation*; D009930:Organic Chemicals / Q000138:chemical synthesis* / Q000737:chemistry; D014867:Water / Q000737:chemistry
chemical_list: D004987:Ethers; D009930:Organic Chemicals; D014867:Water