title: Expanding the regioselective enzymatic repertoire: oxidative mono-cleavage of dialkenes catalyzed by Trametes hirsuta.
abstract: The first report of a biocatalytic regioselective oxidative mono-cleavage of dialkenes was successfully achieved employing a cell-free enzyme preparation from Trametes hirsuta at the expense of molecular oxygen. Selected reactions were performed on a preparative scale affording high to excellent conversions and chemoselectivities.
authors.affiliation: Department of Organic and Inorganic Chemistry, University of Oviedo, Instituto de Biotecnología de Asturias, Calle Julián Clavería 8, 33006 Oviedo, Spain.
authors.forename: Caroline E
authors.initials: CE
authors.lastname: Paul
authors.forename: Aashrita
authors.initials: A
authors.lastname: Rajagopalan
authors.forename: Iván
authors.initials: I
authors.lastname: Lavandera
authors.forename: Vicente
authors.initials: V
authors.lastname: Gotor-Fernández
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Kroutil
authors.forename: Vicente
authors.initials: V
authors.lastname: Gotor
mesh_terms: D000475:Alkenes / Q000138:chemical synthesis / Q000378:metabolism*; D001547:Benzaldehydes / Q000737:chemistry / Q000378:metabolism*; D055162:Biocatalysis; D002474:Cell-Free System; D010084:Oxidation-Reduction; D010100:Oxygen / Q000737:chemistry; D013237:Stereoisomerism; D013379:Substrate Specificity; D055454:Trametes / Q000201:enzymology*
chemical_list: D000475:Alkenes; D001547:Benzaldehydes; D010100:Oxygen