title: Helicobacter pylori persistence in children: distinguishing inadequate treatment, resistant organisms, and reinfection.
abstract: Helicobacter pylori is a worldwide infection that causes chronic gastritis, duodenal ulcers, and malignancy. Transmission of Helicobacter pylori within a family appears to be the predominant mode of contamination. Recurrence of the infection is frequently seen following treatment. Lack of eradication due to either inadequate treatment or resistant bacteria vs. reinfection have been explanations for detection of H. pylori following treatment. In this article we will discuss the concepts of inadequate treatment vs. resistant infection and reinfection as causes of persistent H. pylori infection.
authors.affiliation: Pediatric Gastroenterology Fellow at the Digestive Disease and Nutrition Center, Division of Pediatric Gastroenterology, Women and Children's Hospital of Buffalo, State University of New York at Buffalo, Buffalo, NY 14222, USA. dmoya@upa.chob.edu
authors.forename: Diana A
authors.initials: DA
authors.lastname: Moya
authors.forename: Karen D
authors.initials: KD
authors.lastname: Crissinger
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D024881:Drug Resistance, Bacterial; D004359:Drug Therapy, Combination; D016481:Helicobacter Infections / Q000188:drug therapy* / Q000382:microbiology / Q000635:transmission; D016480:Helicobacter pylori / Q000187:drug effects / Q000302:isolation & purification*; D006801:Humans; D012008:Recurrence; D012307:Risk Factors
chemical_list: D000900:Anti-Bacterial Agents