title: Frequency of gestational diabetes mellitus at collaborating centers based on IADPSG consensus panel-recommended criteria: the Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study.
abstract: OBJECTIVE
  To report frequencies of gestational diabetes mellitus (GDM) among the 15 centers that participated in the Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study using the new International Association of the Diabetes and Pregnancy Study Groups (IADPSG) criteria.
  
  
  METHODS
  All participants underwent a 75-g oral glucose tolerance test between 24 and 32 weeks' gestation. GDM was retrospectively classified using the IADPSG criteria (one or more fasting, 1-h, or 2-h plasma glucose concentrations equal to or greater than threshold values of 5.1, 10.0, or 8.5 mmol/L, respectively).
  
  
  RESULTS
  Overall frequency of GDM was 17.8% (range 9.3-25.5%). There was substantial center-to-center variation in which glucose measures met diagnostic thresholds.
  
  
  CONCLUSIONS
  Although the new diagnostic criteria for GDM apply globally, center-to-center differences occur in GDM frequency and relative diagnostic importance of fasting, 1-h, and 2-h glucose levels. This may impact strategies used for the diagnosis of GDM.
authors.affiliation: Department of Obstetrics and Gynecology, Kaiser Foundation Hospital, Bellflower, California, USA.
authors.forename: David A
authors.initials: DA
authors.lastname: Sacks
authors.forename: David R
authors.initials: DR
authors.lastname: Hadden
authors.forename: Michael
authors.initials: M
authors.lastname: Maresh
authors.forename: Chaicharn
authors.initials: C
authors.lastname: Deerochanawong
authors.forename: Alan R
authors.initials: AR
authors.lastname: Dyer
authors.forename: Boyd E
authors.initials: BE
authors.lastname: Metzger
authors.forename: Lynn P
authors.initials: LP
authors.lastname: Lowe
authors.forename: Donald R
authors.initials: DR
authors.lastname: Coustan
authors.forename: Moshe
authors.initials: M
authors.lastname: Hod
authors.forename: Jeremy J N
authors.initials: JJ
authors.lastname: Oats
authors.forename: Bengt
authors.initials: B
authors.lastname: Persson
authors.forename: Elisabeth R
authors.initials: ER
authors.lastname: Trimble
mesh_terms: D000328:Adult; D001786:Blood Glucose / Q000032:analysis; D016640:Diabetes, Gestational / Q000097:blood / Q000453:epidemiology*; D005260:Female; D005951:Glucose Tolerance Test; D006801:Humans; D006943:Hyperglycemia / Q000097:blood / Q000175:diagnosis; D011247:Pregnancy; D055815:Young Adult
chemical_list: D001786:Blood Glucose