title: Very minimal fluence photodynamic therapy for chronic central serous chorioretinopathy.
abstract: OBJECTIVE
  To describe the safety and efficacy of very minimal fluence photodynamic therapy (PDT) for chronic central serous chorioretinopathy (CSC).
  
  
  METHODS
  Retrospective case series.
  
  
  METHODS
  Five patients with chronic CSC. Two had previously failed alternative therapies, and one was taking concomitant corticosteroids.
  
  
  METHODS
  Patients were treated with very minimal fluence PDT (12 J/cm(2), 150 mW/cm(2), for 80 seconds). Median follow-up time after PDT was 100 days (range, 51 to 154).
  
  
  RESULTS
  All patients experienced an improvement in visual acuity and symptoms, as well as complete resolution of subretinal fluid.
  
  
  CONCLUSIONS
  Very minimal fluence PDT appears to be a safe and effective treatment for chronic CSC. Based on these preliminary findings, a randomized controlled trial is warranted.
authors.affiliation: Department of Ophthalmology & Visual Sciences, University of British Columbia, Vancouver, BC.
authors.forename: Andrea L
authors.initials: AL
authors.lastname: Butler
authors.forename: Adrian T
authors.initials: AT
authors.lastname: Fung
authors.forename: Andrew B
authors.initials: AB
authors.lastname: Merkur
authors.forename: David A
authors.initials: DA
authors.lastname: Albiani
authors.forename: Farzin
authors.initials: F
authors.lastname: Forooghian
mesh_terms: D000328:Adult; D056833:Central Serous Chorioretinopathy / Q000175:diagnosis / Q000188:drug therapy* / Q000503:physiopathology; D002908:Chronic Disease; D005260:Female; D005451:Fluorescein Angiography; D005500:Follow-Up Studies; D006801:Humans; D008027:Light; D008297:Male; D008875:Middle Aged; D010778:Photochemotherapy; D017319:Photosensitizing Agents / Q000627:therapeutic use*; D011166:Porphyrins / Q000627:therapeutic use*; D012189:Retrospective Studies; D016896:Treatment Outcome; D000077362:Verteporfin; D014792:Visual Acuity / Q000502:physiology
chemical_list: D017319:Photosensitizing Agents; D011166:Porphyrins; D000077362:Verteporfin