title: An infant case of dilated cardiomyopathy associated with congenital cytomegalovirus infection.
abstract: A 2-month-old infant with congestive heart failure was referred to the authors' hospital. Echocardiography exhibited a dilated left ventricle (LV), poor LV systolic function, and intraventricular thrombus. Laboratory data showed a normal creatinine phosphokinase level and negative troponin T test results. The congestive heart failure was managed using a beta-blocker, an angiotensin receptor blocker, and diuretics. Head computed tomography performed during the treatment course showed periventricular calcifications. Congenital cytomegalovirus infection was subsequently diagnosed. Fetal echocardiography performed during pregnancy showed impaired LV function, suggesting that the cardiomyopathy was associated with cytomegalovirus infection in utero.
authors.affiliation: Department of Pediatric Cardiology, National Cerebral and Cardiovascular Center, 5-7-1 Fujishiro-dai, Suita, Osaka 565-8565, Japan. hsakaguc@hsp.ncvc.go.jp
authors.forename: Heima
authors.initials: H
authors.lastname: Sakaguchi
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Yamamoto
authors.forename: Shin
authors.initials: S
authors.lastname: Ono
authors.forename: Akiko
authors.initials: A
authors.lastname: Akashi
authors.forename: Etsuko
authors.initials: E
authors.lastname: Tsuda
authors.forename: Ken
authors.initials: K
authors.lastname: Watanabe
mesh_terms: D000998:Antiviral Agents / Q000627:therapeutic use; D015415:Biomarkers / Q000097:blood; D001927:Brain Diseases / Q000000981:diagnostic imaging; D002114:Calcinosis / Q000000981:diagnostic imaging; D002311:Cardiomyopathy, Dilated / Q000151:congenital* / Q000000981:diagnostic imaging / Q000821:virology*; D003586:Cytomegalovirus Infections / Q000150:complications* / Q000000981:diagnostic imaging / Q000188:drug therapy; D003937:Diagnosis, Differential; D004452:Echocardiography; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D015774:Ganciclovir / Q000627:therapeutic use; D006333:Heart Failure / Q000000981:diagnostic imaging / Q000188:drug therapy; D006801:Humans; D007223:Infant; D016133:Polymerase Chain Reaction; D011247:Pregnancy; D014057:Tomography, X-Ray Computed; D016216:Ultrasonography, Prenatal
chemical_list: D000998:Antiviral Agents; D015415:Biomarkers; D015774:Ganciclovir