title: CoSMoS unravels mysteries of transcription initiation.
abstract: Using a fluorescence method called colocalization single-molecule spectroscopy (CoSMoS), Friedman and Gelles dissect the kinetics of transcription initiation at a bacterial promoter. Ultimately, CoSMoS could greatly aid the study of the effects of DNA sequence and transcription factors on both prokaryotic and eukaryotic promoters.
authors.affiliation: Department of Bacteriology, University of Wisconsin-Madison, Madison, WI 53706, USA. rgourse@bact.wisc.edu
authors.forename: Richard L
authors.initials: RL
authors.lastname: Gourse
authors.forename: Robert
authors.initials: R
authors.lastname: Landick