title: Classical presentation of Darier's disease: a rare disorder of keratinisation.
abstract: Keratosis follicularis or Darier's disease (DD), a rare autosomal dominant disorder is characterised clinically by appearance of multiple, prurutic, discrete, scaly papules affecting seborrheic areas coupled with palmar pits, nail changes and mucosal involvement. Histologicaly the lesions show suprabasal clefts with acantholytic and dyskeratotic cells. We report a case of 35 years old woman with typical clinical and histological features of Darier's disease.
authors.affiliation: Department of Dermatology, Shaikh Zayed Federal Postgraduate Medical Institute, Lahore, Pakistan.
authors.forename: Atiya
authors.initials: A
authors.lastname: Mahboob
authors.forename: Faryal
authors.initials: F
authors.lastname: Yaqub
authors.forename: Zahid
authors.initials: Z
authors.lastname: Shahzad
authors.forename: Manaal
authors.initials: M
authors.lastname: Afzaal
authors.forename: Moazzum
authors.initials: M
authors.lastname: Hanif
authors.forename: Deeba Sattar
authors.initials: DS
authors.lastname: Khan
authors.forename: Riffat
authors.initials: R
authors.lastname: Nasim
authors.forename: Aleena
authors.initials: A
authors.lastname: Khan
mesh_terms: D000328:Adult; D001706:Biopsy; D007644:Darier Disease / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans