title: Reactive polymer coatings: a general route to thiol-ene and thiol-yne click reactions.
abstract: Reactive polymer coatings were synthesized via chemical vapor deposition (CVD) polymerization process. These coatings decouple surface design from bulk properties of underlying materials and provide a facile and general route to support thiol-ene and thiol-yne reactions on a variety of substrate materials. Through the reported technique, surface functions can be activated through a simple design of thiol-terminated molecules such as polyethylene glycols (PEGs) or peptides (GRGDYC), and the according biological functions were demonstrated in controlled and low-fouling protein adsorptions as well as accurately manipulated cell attachments.
authors.affiliation: Department of Chemical Engineering, National Taiwan University, Taipei 10617, Taiwan.
authors.forename: Jyun-Ting
authors.initials: JT
authors.lastname: Wu
authors.forename: Chi-Hui
authors.initials: CH
authors.lastname: Huang
authors.forename: Wei-Chieh
authors.initials: WC
authors.lastname: Liang
authors.forename: Yen-Lin
authors.initials: YL
authors.lastname: Wu
authors.forename: Jiashing
authors.initials: J
authors.lastname: Yu
authors.forename: Hsien-Yeh
authors.initials: HY
authors.lastname: Chen
mesh_terms: D000475:Alkenes / Q000737:chemistry; D000480:Alkynes / Q000737:chemistry; D000595:Amino Acid Sequence; D057930:Click Chemistry; D005340:Fibrinogen / Q000737:chemistry; D005740:Gases / Q000737:chemistry; D058105:Polymerization; D011108:Polymers / Q000737:chemistry*; D011806:Quinolinium Compounds / Q000737:chemistry; D013438:Sulfhydryl Compounds / Q000737:chemistry*; D013499:Surface Properties
chemical_list: C481052:Alexa fluor 546; D000475:Alkenes; D000480:Alkynes; D005740:Gases; D011108:Polymers; D011806:Quinolinium Compounds; D013438:Sulfhydryl Compounds; D005340:Fibrinogen