title: [Risk factors of graft-versus-host disease in patients after allogeneic stem cell transplantation].
abstract: BACKGROUND
  Graft-versus-host disease (GVHD) is the most common and most serious complication of allogeneic hematopoetic stem cell transplantation (HSCT). The aim of this study was to assess the incidence of GVHD after allogeneic HSCT depending on the diagnosis and risk factors.
  
  
  METHODS
  The study group comprised 78 patients aged 18 to 61 in whom allogeneic transplantation of hematopoietic stem cell in the Department and Clinic of Hematology, Oncology and Internal Diseases of Medical University in Warsaw (Poland) was performed.
  
  
  RESULTS
  Acute form of GVHD was significantly more often occurred after total body irradiation (TBI) for patients with TBI who did not (p < 0.05).
  
  
  CONCLUSIONS
  Risk factors for aGVHD were: age of the recipient, acute myeloid leukemia, myeloablative conditioning, TBI and unrelated donor.
authors.affiliation: 1Zakład Chorób Błony Sluzowej i Przyzebia IS, WUM, Warszawa. ir.kozak@wp.pl
authors.forename: Irena
authors.initials: I
authors.lastname: Kozak
authors.forename: Jadwiga
authors.initials: J
authors.lastname: Dwilewicz-Trojaczek
authors.forename: Jolanta
authors.initials: J
authors.lastname: Siemińska
authors.forename: Renata
authors.initials: R
authors.lastname: Górska
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D015984:Causality; D005260:Female; D006086:Graft vs Host Disease / Q000453:epidemiology* / Q000209:etiology; D018380:Hematopoietic Stem Cell Transplantation / Q000009:adverse effects / Q000706:statistics & numerical data*; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D011044:Poland / Q000453:epidemiology; D012307:Risk Factors; D033581:Stem Cell Transplantation / Q000009:adverse effects / Q000706:statistics & numerical data*; D014184:Transplantation, Homologous / Q000009:adverse effects / Q000706:statistics & numerical data*; D014916:Whole-Body Irradiation / Q000009:adverse effects / Q000706:statistics & numerical data; D055815:Young Adult