title: The glutamatergic neurotransmission in the central nervous system.
abstract: Glutamate is one of the major neurotrasmitters in mammalian brain and changes in its concentration have been associated with a number of neurological disorders, including neurodegenerative, cerebrovascular diseases and epilepsy. Moreover, recently a possible role for glutamatergic system dysfunction has been suggested also in the peripheral nervous system. This chapter will revise the current knowledge in the distribution of glutamate and of its receptors and transporters in the central nervous system.
authors.affiliation: Department of Neuroscience and Biomedical Technologies, University of Milano-Bicocca, Via Cadore 48, 20900 Monza (MB), Italy. paola.marmiroli@unimib.it
authors.forename: P
authors.initials: P
authors.lastname: Marmiroli
authors.forename: G
authors.initials: G
authors.lastname: Cavaletti
mesh_terms: D026905:Amino Acid Transport Systems / Q000378:metabolism; D000818:Animals; D002490:Central Nervous System / Q000166:cytology / Q000378:metabolism*; D018698:Glutamic Acid / Q000378:metabolism*; D006801:Humans; D017470:Receptors, Glutamate / Q000378:metabolism; D009435:Synaptic Transmission; D050496:Vesicular Glutamate Transport Proteins / Q000378:metabolism
chemical_list: D026905:Amino Acid Transport Systems; D017470:Receptors, Glutamate; D050496:Vesicular Glutamate Transport Proteins; D018698:Glutamic Acid