title: Synthesis of benzisoxazolines by the coupling of arynes with nitrones.
abstract: A variety of substituted benzisoxazolines have been synthesized by the [3 + 2] cycloaddition of nitrones and arynes. The reaction scope is broad, the reaction conditions are mild, and the process tolerates a variety of functional groups.
authors.affiliation: Department of Chemistry, Iowa State University, Ames, Iowa 50011, USA.
authors.forename: Chun
authors.initials: C
authors.lastname: Lu
authors.forename: Anton V
authors.initials: AV
authors.lastname: Dubrovskiy
authors.forename: Richard C
authors.initials: RC
authors.lastname: Larock
mesh_terms: D001555:Benzene Derivatives / Q000737:chemistry*; D003500:Cyclization; D007555:Isoxazoles / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D009589:Nitrogen Oxides / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D001555:Benzene Derivatives; D007555:Isoxazoles; D009589:Nitrogen Oxides; C524146:benzyne; C015388:nitrones