title: [Investigate the impact of hepatitis B virus infection on sperm DNA integrity].
abstract: OBJECTIVE
  Investigated the impact of HBV infection on sperm DNA integrity and its applied significance.
  
  
  METHODS
  12 cases infertility male with HBV infection in patient group and 11 cases of normal male without HBV infection in the control group were by SCD and CASA.
  
  
  RESULTS
  The DFI in the patient group was (23.4 +/- 10.2)%, while it was in the control group was (11.6 +/- 5.9)%. The difference of the DFI in these two groups was significantly, P < 0.01. The sperm concentration and forward motility (a + b) in the patient group were lower than that in the control group, P < 0.01. There were also significantly of the normal sperm and sperm activity between the two groups.
  
  
  CONCLUSIONS
  HBV infection not only affected the conventional semen parameters, but also caused serious damage on sperm DNA.
authors.affiliation: Ningbo Traditional Chinese Medicine Attached to Zhejiang Traditional Chinese Medicine University, Ningbo 351012, China. cjw4015@sina.com
authors.forename: Jian-Wei
authors.initials: JW
authors.lastname: Chen
authors.forename: Yun
authors.initials: Y
authors.lastname: Cui
authors.forename: Xiao-Xia
authors.initials: XX
authors.lastname: Zhang
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D004249:DNA Damage; D006509:Hepatitis B / Q000150:complications*; D006515:Hepatitis B virus / Q000502:physiology*; D006801:Humans; D007248:Infertility, Male / Q000209:etiology / Q000235:genetics* / Q000821:virology; D008297:Male; D013076:Sperm Count; D013081:Sperm Motility; D013094:Spermatozoa / Q000166:cytology* / Q000378:metabolism