title: Synthetic polymer nanoparticles conjugated with FimH(A) from E. coli pili to emulate the bacterial mode of epithelial internalization.
abstract: Amphiphilic block copolymer nanoparticles are conjugated with uropathogenic  Escherichia coli  type 1 pilus adhesin FimH(A) through amidation chemistry to enable bladder epithelial cell binding and internalization of the nanoparticles in vitro.
authors.affiliation: Department of Chemistry and Chemical Engineering, Texas A&M University, P.O. Box 30012, College Station, Texas 77842, USA.
authors.forename: Lily Yun
authors.initials: LY
authors.lastname: Lin
authors.forename: Kristin M
authors.initials: KM
authors.lastname: Tiemann
authors.forename: Yali
authors.initials: Y
authors.lastname: Li
authors.forename: Jerome S
authors.initials: JS
authors.lastname: Pinkner
authors.forename: Jennifer N
authors.initials: JN
authors.lastname: Walker
authors.forename: Scott J
authors.initials: SJ
authors.lastname: Hultgren
authors.forename: David A
authors.initials: DA
authors.lastname: Hunstad
authors.forename: Karen L
authors.initials: KL
authors.lastname: Wooley
mesh_terms: D018830:Adhesins, Escherichia coli / Q000737:chemistry*; D004847:Epithelial Cells / Q000166:cytology*; D004926:Escherichia coli / Q000737:chemistry* / Q000166:cytology*; D036781:Fimbriae Proteins / Q000737:chemistry*; D008958:Models, Molecular; D053758:Nanoparticles / Q000737:chemistry*; D010316:Particle Size; D011108:Polymers / Q000138:chemical synthesis* / Q000737:chemistry; D013499:Surface Properties
chemical_list: D018830:Adhesins, Escherichia coli; D011108:Polymers; C058769:fimH protein, E coli; D036781:Fimbriae Proteins