title: Commercialization of microfluidic point-of-care diagnostic devices.
abstract: A large part of the excitement behind microfluidics is in its potential for producing practical devices, but surprisingly few lab-on-a-chip based technologies have been successfully introduced into the market. Here, we review current work in commercializing microfluidic technologies, with a focus on point-of-care diagnostics applications. We will also identify challenges to commercialization, including lessons drawn from our experience in Claros Diagnostics. Moving forward, we discuss the need to strike a balance between achieving real-world impact with integrated devices versus design of novel single microfluidic components.
authors.affiliation: Department of Biomedical Engineering, Columbia University, New York, NY, USA.
authors.forename: Curtis D
authors.initials: CD
authors.lastname: Chin
authors.forename: Vincent
authors.initials: V
authors.lastname: Linder
authors.forename: Samuel K
authors.initials: SK
authors.lastname: Sia
mesh_terms: D004247:DNA / Q000032:analysis; D033161:Government Regulation; D015658:HIV Infections / Q000175:diagnosis; D006801:Humans; D007118:Immunoassay; D007221:Industry; D046210:Microfluidic Analytical Techniques / Q000191:economics / Q000295:instrumentation* / Q000379:methods; D019095:Point-of-Care Systems / Q000191:economics; D013601:T-Lymphocytes / Q000166:cytology / Q000378:metabolism
chemical_list: D004247:DNA