title: [Histopathological study of 268 hepatic allograft biopsies].
abstract: OBJECTIVE
  To observe the histopathological features of posttransplant complications for hepatic allografts and evaluate their biopsy values.
  
  
  METHODS
  From January 1999 to May 2011, a total of 268 percutaneous hepatic allograft biopsies were conducted in 207 recipients and the diagnostic procedures for staining, classification and staging performed according to the Banff schema and Chinese Schema on hepatic allograft rejection.
  
  
  RESULTS
  Among them, there were ischemia/reperfusion injury (n = 26, 9.7%), acute T cell-mediated rejection (n = 83, 31.0%), acute antibody-mediated rejection (n = 12, 4.5%), chronic posttransplantation rejection (n = 31, 11.6%), immunosuppressive-induced liver injury (n = 70, 26.1%) and recurrent diseases (n = 18, 6.7%). Acute T cell-mediated rejection and drug-induced liver injury were two most common causes of allograft dysfunctions.
  
  
  CONCLUSIONS
  Percutaneous hepatic allograft biopsy is valuable for the diagnosis and evaluation of various posttransplantation complications.
authors.affiliation: Huazhong University of Science & Technology, Wuhan, China.
authors.forename: Hui
authors.initials: H
authors.lastname: Guo
authors.forename: Zhong-hua
authors.initials: ZH
authors.lastname: Chen
authors.forename: Zhi-shui
authors.initials: ZS
authors.lastname: Chen
authors.forename: Fan-jun
authors.initials: FJ
authors.lastname: Zeng
authors.forename: Chang-sheng
authors.initials: CS
authors.lastname: Ming
authors.forename: Wei-jie
authors.initials: WJ
authors.lastname: Zhang
authors.forename: Bin
authors.initials: B
authors.lastname: Liu
authors.forename: Nian-qiao
authors.initials: NQ
authors.lastname: Gong
authors.forename: Ji-Pin
authors.initials: JP
authors.lastname: Jiang
authors.forename: Lai
authors.initials: L
authors.lastname: Wei
authors.forename: Dun-feng
authors.initials: DF
authors.lastname: DU
authors.forename: Hui-bo
authors.initials: HB
authors.lastname: Shi
authors.forename: Xiao-ping
authors.initials: XP
authors.lastname: Chen
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001707:Biopsy, Needle; D002648:Child; D005260:Female; D006801:Humans; D008099:Liver / Q000503:physiopathology*; D016031:Liver Transplantation / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D012189:Retrospective Studies; D055815:Young Adult