title: Lysozyme pattern formation in evaporating drops.
abstract: Liquid droplets containing suspended particles deposited on a solid, flat surface generally form ringlike structures due to the redistribution of solute during evaporation (the "coffee ring effect"). The forms of the deposited patterns depend on interactions between solute(s), solvent, and substrate. In this study, deposition patterns from droplets of a simplified model biological fluid (DI water + lysozyme) are examined by scanning probe and optical microscopy. The overall lysozyme residue morphology is complex (with both a perimeter "rim" and undulating interior) but varies little with concentration. However, the final packing of lysozyme molecules is strongly dependent on initial concentration.
authors.affiliation: Department of Mechanical Engineering and Materials Science, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, United States. hlm32@pitt.edu
authors.forename: Heather Meloy
authors.initials: HM
authors.lastname: Gorr
authors.forename: Joshua M
authors.initials: JM
authors.lastname: Zueger
authors.forename: John A
authors.initials: JA
authors.lastname: Barnard
mesh_terms: D008853:Microscopy; D009113:Muramidase / Q000737:chemistry*; D010316:Particle Size; D012996:Solutions / Q000737:chemistry
chemical_list: D012996:Solutions; D009113:Muramidase