title: Gliclazide impurity F: N-[(perhydro-cyclo-penta-[c]pyrrol-2-yl)amino-carbon-yl]-o-toluene-sulfonamide.
abstract: The title compound, C(15)H(21)N(3)O(3)S, is known to be an impurity of gliclazide [systematic name: N-(hexa-hydro-1H-cyclopenta[c]pyrrol-2-ylcarbamo-yl)-4-methyl-benzene-sulfonamide], a sul-fonyl-urea anti-diabetic drug. Gliclazide has a p-tolyl group substituting the sulfonamide functionality, while the title mol-ecule contains an o-tolyl group. Both five-membered fused rings adopt envelope conformations. In the crystal, N-H⋯O hydrogen bonds are formed between HN(C=O)NH groups, building centrosymmetric dimers. These dimers are further linked through N-H⋯O(sulfon-yl) contacts, forming chains in [100].
authors.forename: Di
authors.initials: D
authors.lastname: Wu
authors.forename: Xueyuan
authors.initials: X
authors.lastname: Wang
authors.forename: Dongying
authors.initials: D
authors.lastname: Pang
authors.forename: Wei
authors.initials: W
authors.lastname: Su
authors.forename: Yan
authors.initials: Y
authors.lastname: Sun