title: A portable continuous blood purification machine for emergency rescue in disasters.
abstract: BACKGROUND
  Continuous renal replacement therapy plays an important role in emergency rescue. Currently, no continuous renal replacement therapy machine can be used under unstable conditions as the fluid flow of these machines is controlled electronically. A novel machine that can provide emergency continuous renal replacement therapy in disaster rescue is therefore needed.
  
  
  METHODS
  Based on a volumetric metering method, a prototype portable continuous blood purifier based on a volumetric metering method was developed. Basic performance tests, special environmental tests, animal experiments and clinical use of the novel machine were completed to test and verify its performance under unstable conditions.
  
  
  RESULTS
  All tests completed showed that the machine met the requirements of the national industry standards with a size reduced to approximately one half of the Baxter Aquarius machine. The clearance of harmful substances by the machine described here was equal to that of the Baxter Aquarius machine and was adequate for clinical purposes.
  
  
  CONCLUSIONS
  The novel prototype performed well in all situations tested and can aid rescue work on disaster sites.
authors.affiliation: Department of Nephrology, General Hospital of the Navy, Second Military Medical University, Beijing, China.
authors.forename: Ping
authors.initials: P
authors.lastname: He
authors.forename: Chunhua
authors.initials: C
authors.lastname: Zhou
authors.forename: Hongyan
authors.initials: H
authors.lastname: Li
authors.forename: Yongwu
authors.initials: Y
authors.lastname: Yu
authors.forename: Zhen
authors.initials: Z
authors.lastname: Dong
authors.forename: Yuanyuan
authors.initials: Y
authors.lastname: Wen
authors.forename: Ping
authors.initials: P
authors.lastname: Li
authors.forename: Wenhong
authors.initials: W
authors.lastname: Tang
authors.forename: Xue
authors.initials: X
authors.lastname: Wang
mesh_terms: D058186:Acute Kidney Injury / Q000097:blood / Q000503:physiopathology / Q000628:therapy*; D000328:Adult; D000368:Aged; D000818:Animals; D004285:Dogs; D004632:Emergency Medical Services; D004867:Equipment Design; D005260:Female; D006440:Hemofiltration / Q000295:instrumentation; D006801:Humans; D007668:Kidney / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D017582:Renal Replacement Therapy / Q000295:instrumentation*