title: Chromatin and transcription in yeast.
abstract: Understanding the mechanisms by which chromatin structure controls eukaryotic transcription has been an intense area of investigation for the past 25 years. Many of the key discoveries that created the foundation for this field came from studies of Saccharomyces cerevisiae, including the discovery of the role of chromatin in transcriptional silencing, as well as the discovery of chromatin-remodeling factors and histone modification activities. Since that time, studies in yeast have continued to contribute in leading ways. This review article summarizes the large body of yeast studies in this field.
authors.affiliation: Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts 01605, USA.
authors.forename: Oliver J
authors.initials: OJ
authors.lastname: Rando
authors.forename: Fred
authors.initials: F
authors.lastname: Winston
mesh_terms: D002843:Chromatin / Q000737:chemistry / Q000235:genetics* / Q000378:metabolism*; D042002:Chromatin Assembly and Disassembly; D006657:Histones / Q000378:metabolism; D009707:Nucleosomes / Q000378:metabolism; D016366:Open Reading Frames; D012045:Regulatory Sequences, Nucleic Acid; D012441:Saccharomyces cerevisiae / Q000235:genetics* / Q000378:metabolism*; D014157:Transcription Factors / Q000378:metabolism; D014158:Transcription, Genetic; D015533:Transcriptional Activation
chemical_list: D002843:Chromatin; D006657:Histones; D009707:Nucleosomes; D014157:Transcription Factors