title: Three down and one to go: modeling medulloblastoma subgroups.
abstract: In this issue of Cancer Cell, Pei et al. and Kawauchi et al. describe murine models of an aggressive medulloblastoma subtype driven by Myc. These tumors have a cellular origin, microscopic appearance, and molecular profile distinct from those of three other major subgroups. Thus, the models fill a significant clinical need.
authors.affiliation: Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. ceberha@jhmi.edu
authors.forename: Charles G
authors.initials: CG
authors.lastname: Eberhart