title: [Cushing syndrome and pregnancy: a propos of a malignant adrenocortical carcinoma].
abstract: Cushing's syndrome is a rare condition in the general population (1/1000000) and is even less common during pregnancy. We report the case of a patient cared at 27 weeks of gestation (wg) for hypertension and electolyte disturbances. Cushing's syndrome was confirmed by salivary cortisol and ACTH assessment. RMN revealed a 9 cm left adrenal tumor. Severe hypertension and electolyte disturbances on the one hand, and diagnostic uncertainty on the other hand, imposed adrenalectomy at 29 wg. Twelve days later, fetal distress led to a caesarian section and birth of a well being male baby.
authors.affiliation: Service de gynécologie obstétrique et médecine de la reproduction, CHU de Brest, Brest, France. lionelhomer@yahoo.fr
authors.forename: L
authors.initials: L
authors.lastname: Homer
authors.forename: M
authors.initials: M
authors.lastname: Viatge
authors.forename: F-X
authors.initials: FX
authors.lastname: Gayet
authors.forename: Y
authors.initials: Y
authors.lastname: Laurent
authors.forename: V
authors.initials: V
authors.lastname: Kerlan
mesh_terms: D000310:Adrenal Gland Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D000315:Adrenalectomy; D018268:Adrenocortical Carcinoma / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D000324:Adrenocorticotropic Hormone / Q000097:blood; D000328:Adult; D003480:Cushing Syndrome / Q000175:diagnosis* / Q000209:etiology / Q000601:surgery; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000032:analysis; D006973:Hypertension / Q000175:diagnosis* / Q000209:etiology; D007231:Infant, Newborn; D050498:Live Birth; D008279:Magnetic Resonance Imaging; D008297:Male; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000175:diagnosis* / Q000601:surgery; D012463:Saliva / Q000737:chemistry; D012720:Severity of Illness Index
chemical_list: D000324:Adrenocorticotropic Hormone; D006854:Hydrocortisone