title: Transapical versus conventional aortic valve replacement--a propensity-matched comparison.
abstract: BACKGROUND
  The goal of this study was to compare the short- and long-term outcomes after aortic valve (AV) surgery carried out via standard sternotomy/partial sternotomy versus transapical transcatheter AV implantation (taTAVI).
  
  
  METHODS
  All 336 patients who underwent taTAVI between 2006 and 2010 were compared with 4533 patients who underwent conventional AV replacement (AVR) operations between 2001 and 2010. Using propensity score matching, we identified and consecutively compared 2 very similar groups of 167 patients each. The focus was on periprocedural complications and long-term survival.
  
  
  RESULTS
  The 30-day mortality rate was 10.8% and 8.4% (P = .56) for the conventional AVR patients and the TAVI patients, respectively. The percentages of postoperative pacemaker implantations (15.0% versus 6.0%, P = .017) and cases of renal failure requiring dialysis (25.7% versus 12.6%, P = .004) were higher in the TAVI group. Kaplan-Meier curves diverged after half a year in favor of conventional surgery. The estimated 3-year survival rates were 53.5% ± 5.7% (TAVI) and 66.7% ± 0.2% (conventional AVR).
  
  
  CONCLUSIONS
  Our study shows that even with all the latest successes in catheter-based AV implantation, the conventional surgical approach is still a very good treatment option with excellent long-term results, even for older, high-risk patients.
authors.affiliation: Department of Cardiac Surgery, Heart Center Leipzig, Leipzig, Germany. dholzhey@web.de
authors.forename: David M
authors.initials: DM
authors.lastname: Holzhey
authors.forename: William
authors.initials: W
authors.lastname: Shi
authors.forename: A
authors.initials: A
authors.lastname: Rastan
authors.forename: Michael A
authors.initials: MA
authors.lastname: Borger
authors.forename: Martin
authors.initials: M
authors.lastname: Hänsig
authors.forename: Friedrich W
authors.initials: FW
authors.lastname: Mohr
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001021:Aortic Valve / Q000473:pathology* / Q000601:surgery; D005260:Female; D005858:Germany; D006349:Heart Valve Diseases / Q000401:mortality / Q000473:pathology* / Q000601:surgery; D019918:Heart Valve Prosthesis Implantation / Q000295:instrumentation / Q000379:methods*; D006801:Humans; D053208:Kaplan-Meier Estimate; D008297:Male; D057216:Propensity Score; D012189:Retrospective Studies; D013223:Statistics as Topic; D011795:Surveys and Questionnaires