title: Pd-catalyzed direct arylation of polyfluoroarenes on water under mild conditions using PPh3 ligand.
abstract: We report a Pd-catalyzed direct arylation of polyfluoroarenes with aryl iodides. The advantages of this reaction are its high reaction efficiency, excellent functional group compatibility, mild reaction conditions (70 °C), inexpensive PPh(3) ligand, and use of pure water as reaction medium. The usefulness of this reaction has also been demonstrated by rapid preparation of highly functionalized polyfluoroarenes via iterative Pd-catalyzed C-H bond functionalization.
authors.affiliation: Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, China.
authors.forename: Fei
authors.initials: F
authors.lastname: Chen
authors.forename: Qiao-Qiao
authors.initials: QQ
authors.lastname: Min
authors.forename: Xingang
authors.initials: X
authors.lastname: Zhang