title: Patient perception of Levido reticularis due to amantadine.
abstract: Livedo reticularis (LR) is a "fish-net like" mottling of the skin, and is attributed to a variety of factors. Amantadine, a medication used in Parkinson's disease, has been known to cause LR localized to the lower, and to a rarer extent, the upper extremities. Patient perception of this condition has been severely under-reported and can impact the patient's decision to stop this medication. In this retrospective study, we analyze the perception of five patients presenting with LR and their decision to continue on amantadine. It was seen that patients with the reticularis rash localized in the upper extremities, in addition to the lower extremities, were affected enough to discontinue amantadine despite its useful therapeutic effects. It is imperative that patient perception regarding LR be taken into consideration when initially presented. Furthermore, the decision to change the regiment of amantadine should be individualized according to patient condition and perception of presented rash.
authors.affiliation: Parkinson's Clinic of Eastern Toronto & Movement Disorders Center, Toronto, Ontario, Canada. ranaaq@yahoo.com
authors.forename: Abdul Qayyum
authors.initials: AQ
authors.lastname: Rana
authors.forename: Mohamed Sufian
authors.initials: MS
authors.lastname: Masroor
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000547:Amantadine / Q000009:adverse effects*; D000978:Antiparkinson Agents / Q000009:adverse effects*; D005260:Female; D006801:Humans; D054068:Livedo Reticularis / Q000139:chemically induced*; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000188:drug therapy; D012189:Retrospective Studies
chemical_list: D000978:Antiparkinson Agents; D000547:Amantadine