title: Reproducibility and effect of posture on impulse oscillation parameters in persons with spinal cord injury.
abstract: BACKGROUND
  The impulse oscillation system (IOS) offers significant value in the assessment of airway dynamics in persons with spinal cord injury (SCI) because of minimal patient effort but measurement reproducibility in SCI is unknown.
  
  
  OBJECTIVE
  To evaluate  between-day reproducibility and the effect of posture on airway resistance [respiratory resistances at 5 Hz (R5) and 20 Hz (R20)] in subjects with tetraplegia, paraplegia and able-bodied controls.
  
  
  METHODS
  Ten subjects with tetraplegia, 10 subjects with paraplegia and 11 able-bodied  individuals were evaluated using IOS. Three 30 second trials were obtained in each while in the seated and supine position on Day 1, and repeated on Day 2.
  
  
  RESULTS
  The within-day coefficient of variation (CV%) for R5 and R20 were comparable in the 3 study groups in the seated  and supine positions. Compared to controls, the between-day CV% for the combined data was higher in subjects with tetraplegia and paraplegia for R5 seated, and was higher in subjects with tetraplegia for R5 supine.
  
  
  CONCLUSIONS
  IOS has applicability to the study of within-day  respiratory resistance in SCI. However, performing longer-term studies in subjects with tetraplegia and paraplegia may be problematic because of the greater variability for R5 when compared to able-bodied individuals.
authors.affiliation: James J. Peters VA Medical Center, Bronx, NY, USA. christopher.cirnigliaro@va.gov
authors.forename: Christopher M
authors.initials: CM
authors.lastname: Cirnigliaro
authors.forename: Marvin
authors.initials: M
authors.lastname: Lesser
authors.forename: Jeremy
authors.initials: J
authors.lastname: Moyer
authors.forename: Steven C
authors.initials: SC
authors.lastname: Kirshblum
authors.forename: William A
authors.initials: WA
authors.lastname: Bauman
authors.forename: Ann M
authors.initials: AM
authors.lastname: Spungen
mesh_terms: D000328:Adult; D000403:Airway Resistance / Q000502:physiology*; D000704:Analysis of Variance; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009991:Oscillometry; D010264:Paraplegia / Q000503:physiopathology*; D011187:Posture; D011782:Quadriplegia / Q000503:physiopathology*; D015203:Reproducibility of Results; D013997:Time Factors