title: Comment on "Rapid cancer detection by topically spraying a γ-glutamyltranspeptidase-activated fluorescent probe".
abstract: A recent report from Urano et al. described the development of near-infrared (NIR) probes for cancer detection using chemical bioconjugation of targeting agents. Here, I highlight an alternative strategy to develop cancer-selective NIR imaging and theranostic agents without chemical conjugation.
authors.forename: Chunmeng
authors.initials: C
authors.lastname: Shi
mesh_terms: D000818:Animals; D055088:Early Detection of Cancer / Q000379:methods*; D005260:Female; D005456:Fluorescent Dyes / Q000008:administration & dosage* / Q000032:analysis*; D006801:Humans; D009369:Neoplasms / Q000175:diagnosis*; D005723:gamma-Glutamyltransferase / Q000378:metabolism*
chemical_list: D005456:Fluorescent Dyes; D005723:gamma-Glutamyltransferase