title: Nanomaterials for targeted detection and photothermal killing of bacteria.
abstract: Despite the modern treatment processes, contamination of food, water and medical equipment by pathogenic bacteria is very common in this world. Since the last two decades, one of the most important and complex problems our society has been facing is that several human pathogens became resistant to most of the clinically approved antibiotics. Recent advancement in nanoscience and nanotechnology has expanded our ability to design and construct nanomaterials with targeting, therapeutic, and diagnostic functions. These multifunctional materials have attracted our attention to be used as the promising tool for selective bacteria sensing and therapy without the current drugs. This tutorial review provides the basic concepts and critical properties of the different nanostructures that are useful for the pathogen detection and photothermal applications. In addition, bio-conjugated nanomaterial based strategies have been discussed with the aim to provide readers an overview of exciting opportunities and challenges in this field.
authors.affiliation: Department of Chemistry, Jackson State University, Jackson, MS 39217, USA. paresh.c.ray@jsums.edu
authors.forename: Paresh Chandra
authors.initials: PC
authors.lastname: Ray
authors.forename: Sadia Afrin
authors.initials: SA
authors.lastname: Khan
authors.forename: Anant Kumar
authors.initials: AK
authors.lastname: Singh
authors.forename: Dulal
authors.initials: D
authors.lastname: Senapati
authors.forename: Zhen
authors.initials: Z
authors.lastname: Fan
mesh_terms: D000818:Animals; D001419:Bacteria / Q000187:drug effects / Q000302:isolation & purification* / Q000378:metabolism / Q000528:radiation effects*; D004337:Drug Carriers / Q000737:chemistry / Q000378:metabolism / Q000633:toxicity; D006801:Humans; D050296:Microbial Viability / Q000187:drug effects / Q000528:radiation effects; D057054:Molecular Imaging; D049329:Nanostructures / Q000633:toxicity; D013050:Spectrometry, Fluorescence
chemical_list: D004337:Drug Carriers