title: [Combined three-dimensional conformal radiotherapy plus transcatheter arterial chemoembolization and surgical intervention for portal vein tumor thrombus in patients with hepatocellular carcinoma].
abstract: OBJECTIVE
  To explore the clinical therapeutic efficacies of combined three-dimensional conformal radiotherapy (3DCRT) plus transcatheter arterial chemoembolization (TACE) for portal vein tumor thrombus (PVTT) in hepatocellular carcinoma (HCC).
  
  
  METHODS
  A total of 145 HCC patients with tumor thrombus in portal vein were divided randomly into 2 groups. Group A (n = 64) was treated with surgical intervention alone while group B (n = 81) underwent 3DCRT plus TACE. The gross tumor volume (GTV) was defined as PVTT only.
  
  
  RESULTS
  Survival rates of group A at year 1 and 2 were 40.3% and 21.9% with a mean survival time (MST) of 15.2 months while that of group B were 41.2% and 22.5% with a MST of 15.8 months. The total effective rates of groups A and B was 40.6% (28/64) and 44.4% (36/81) respectively.
  
  
  CONCLUSIONS
  The therapeutic efficacy of 3DCRT plus TACE is similar to that of surgical intervention.
authors.affiliation: Nantong Tumor Hospital, Nantong 226361, China.
authors.forename: Zhi-jun
authors.initials: ZJ
authors.lastname: Wu
authors.forename: Jing
authors.initials: J
authors.lastname: Cai
authors.forename: Ai-bing
authors.initials: AB
authors.lastname: Xu
authors.forename: Xiao-qin
authors.initials: XQ
authors.lastname: Su
authors.forename: Xiang-qian
authors.initials: XQ
authors.lastname: Wang
authors.forename: Yi-xin
authors.initials: YX
authors.lastname: Zhang
authors.forename: Bing-feng
authors.initials: BF
authors.lastname: Shao
authors.forename: Yong-jun
authors.initials: YJ
authors.lastname: Li
authors.forename: Kai-yue
authors.initials: KY
authors.lastname: Chu
mesh_terms: D000328:Adult; D000368:Aged; D006528:Carcinoma, Hepatocellular / Q000473:pathology / Q000628:therapy*; D003131:Combined Modality Therapy; D004621:Embolization, Therapeutic; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000473:pathology / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D009360:Neoplastic Cells, Circulating; D011169:Portal Vein / Q000473:pathology; D020266:Radiotherapy, Conformal / Q000379:methods*; D013927:Thrombosis / Q000473:pathology*; D016896:Treatment Outcome; D055815:Young Adult