title: Intramolecular chiral communication in peptide-dendron hybrids.
abstract: The conformational properties of a series of peptide-dendron hybrids progressively incorporating 1-4 dendritic side chains were investigated by circular dichroism. Although the presence of multiple adjacent dendrons along the peptide backbone precluded the formation of α-helical or β-sheet secondary structure, intramolecular packing of the dendrons mediated efficient peptide → dendron chirality transfer in both organic and aqueous media.
authors.affiliation: Dow AgroSciences LLC, Actives to Products, Building 306, Indianapolis, IN 46268, USA. hshao@dow.com
authors.forename: Hui
authors.initials: H
authors.lastname: Shao
authors.forename: Nicholas A
authors.initials: NA
authors.lastname: Bewick
authors.forename: Jon R
authors.initials: JR
authors.lastname: Parquette
mesh_terms: D000873:Anthracenes / Q000737:chemistry*; D015394:Molecular Structure; D010455:Peptides / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000873:Anthracenes; D010455:Peptides; C501244:dendron