title: A disulfide bound-molecular beacon as a fluorescent probe for the detection of reduced glutathione and its application in cells.
abstract: A disulfide-bound molecular beacon (MB) is reported to respond sensitively to changing levels of glutathione in vitro. Importantly, this successful application of a MB has exciting potential for monitoring cellular thiol.
authors.affiliation: State Key Laboratory Base of Eco-Chemical Engineering, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, China. yingshug@126.com
authors.forename: Yingshu
authors.initials: Y
authors.lastname: Guo
authors.forename: Hao
authors.initials: H
authors.lastname: Wang
authors.forename: Yuanshun
authors.initials: Y
authors.lastname: Sun
authors.forename: Bin
authors.initials: B
authors.lastname: Qu
mesh_terms: D004220:Disulfides / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000737:chemistry*; D005978:Glutathione / Q000032:analysis*; D006801:Humans; D020014:K562 Cells; D010084:Oxidation-Reduction; D013050:Spectrometry, Fluorescence; D013438:Sulfhydryl Compounds / Q000032:analysis*
chemical_list: D004220:Disulfides; D005456:Fluorescent Dyes; D013438:Sulfhydryl Compounds; D005978:Glutathione