title: Temporal bone giant cell tumour: report of a second primary giant cell tumour of the temporal bone and infratemporal fossa.
abstract: OBJECTIVE
  To report a second primary giant cell tumour (GCT) of the temporal bone and infratemporal fossa.
  
  
  METHODS
  Medical records were analyzed in the context of the available literature.
  
  
  RESULTS
  A 30 year-old male developed a temporal bone GCT with infratemporal fossa extension 12 years after undergoing successful surgical treatment of a GCT of the femur. These tumours were histologically distinct, suggesting the development of a second primary GCT rather than metastatic disease. This case differs from prior reported cases by surgical approach. Complete removal was achieved but required resection of the zygomatic arch and dissection of all upper facial nerve branches. The patient is disease free after 3 years with acceptable functional and cosmetic results.
  
  
  CONCLUSIONS
  Complete resection of GCTs of the temporal bone and infratemporal fossa is advocated. Surgical techniques that allow for visualization of the facial nerve and increase surgical access can enhance overall clinical success.
authors.affiliation: Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA 02114, USA. Daniel_Roberts@meei.harvard.edu
authors.forename: D S
authors.initials: DS
authors.lastname: Roberts
authors.forename: W C
authors.initials: WC
authors.lastname: Faquin
authors.forename: D G
authors.initials: DG
authors.lastname: Deschler
mesh_terms: D001859:Bone Neoplasms / Q000473:pathology*; D005154:Facial Nerve / Q000601:surgery; D005266:Femoral Neoplasms / Q000601:surgery; D018212:Giant Cell Tumor of Bone / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008297:Male; D016609:Neoplasms, Second Primary / Q000473:pathology* / Q000601:surgery; D013701:Temporal Bone; D055815:Young Adult; D015050:Zygoma / Q000601:surgery*