title: Emerging therapies for the management of traumatized immature permanent incisors.
abstract: Early loss of immature permanent teeth due to pulpal necrosis secondary to trauma can have dire consequences for a child's growth and development. The treatment alternatives include surgical endodontics, traditional calcium hydroxide apexification, and mineral trioxide aggregate (MTA)  apexification. These options pose potential complications, including: arrest of root development; weakened dentinal walls; and increased potential for fracture. Revascularization of the dentin-pulp complex is a new approach that involves disinfecting the root canal system followed by tissue  repair and regeneration while allowing for continued root development and thickening of the lateral dentinal walls through deposition of new hard tissue. The purpose of this report was to present the revascularization of an immature permanent maxillary central incisor that had evidence of  external root resorption. Six months later, internal bleaching was performed to remove cervical discoloration from the triple antibiotic paste. At 18 months, the tooth remained vital and had evidence of continued root development.
authors.forename: Elizabeth K
authors.initials: EK
authors.lastname: Miller
authors.forename: Jessica Y
authors.initials: JY
authors.lastname: Lee
authors.forename: Peter Z
authors.initials: PZ
authors.lastname: Tawil
authors.forename: Fabricio B
authors.initials: FB
authors.lastname: Teixeira
authors.forename: William F
authors.initials: WF
authors.lastname: Vann
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D056624:Apexification; D002648:Child; D003782:Dental Pulp / Q000098:blood supply*; D019229:Dentition, Permanent; D004318:Doxycycline / Q000627:therapeutic use; D006801:Humans; D007180:Incisor / Q000254:growth & development / Q000293:injuries*; D008297:Male; D008437:Maxilla; D018919:Neovascularization, Physiologic; D010516:Periodontal Splints; D012038:Regeneration; D012390:Root Canal Therapy / Q000379:methods; D012391:Root Resorption / Q000209:etiology; D019227:Tooth Apex / Q000254:growth & development*; D014084:Tooth Avulsion / Q000150:complications / Q000628:therapy*; D014073:Tooth Bleaching; D018677:Tooth Injuries / Q000628:therapy*; D014090:Tooth Replantation
chemical_list: D000900:Anti-Bacterial Agents; D004318:Doxycycline