title: Gold catalysis on immobilized substrates: a heteroannulation approach to the solid-supported synthesis of indoles.
abstract: A gold-catalyzed cyclization of immobilized 2-alkynylanilines was developed as the key step in the synthetic sequence for the preparation of 2-substituted indoles. These results demonstrate the potential of the unexplored combination of gold catalysis and solid-phase organic synthesis.
authors.affiliation: Instituto de Química Rosario (CONICET-UNR), Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario, Suipacha 531, 2000-Rosario, Argentina.
authors.forename: Agustina
authors.initials: A
authors.lastname: La-Venia
authors.forename: Sebastián A
authors.initials: SA
authors.lastname: Testero
authors.forename: Mirta P
authors.initials: MP
authors.lastname: Mischne
authors.forename: Ernesto G
authors.initials: EG
authors.lastname: Mata
mesh_terms: D002384:Catalysis; D003500:Cyclization; D006046:Gold / Q000737:chemistry*; D007211:Indoles / Q000138:chemical synthesis*; D015394:Molecular Structure
chemical_list: D007211:Indoles; D006046:Gold