title: Dapsone Hypersensitivity Syndrome That Occurred during Treatment of Pediatric Patient with Erythema Elevatum Diutinum.
abstract: Herein, we report a case of an 8-year-old girl with dapsone hypersensitivity syndrome (DHS) that occurred during the treatment of erythema elevatum diutinum. She had fever, gross hematuria, and malaise for three weeks after initiation of dapsone therapy. Five days after stopping dapsone treatment, she returned to the emergency clinic because of high fever, emesis, diarrhea, upper respiratory symptoms, and worsening of exanthematous eruptions. A diagnosis of DHS was made, and it improved with oral prednisone. We recommend that pediatric patients who are treated with dapsone need to be observed carefully for the development of DHS.
authors.affiliation: Department of Dermatology, Pusan National University School of Medicine, and Biomedical Research Institutue, Pusan National University Hospital, Busan, Korea.
authors.forename: Gun-Wook
authors.initials: GW
authors.lastname: Kim
authors.forename: Hyun-Je
authors.initials: HJ
authors.lastname: Park
authors.forename: Hoon-Soo
authors.initials: HS
authors.lastname: Kim
authors.forename: Su-Han
authors.initials: SH
authors.lastname: Kim
authors.forename: Hyun-Chang
authors.initials: HC
authors.lastname: Ko
authors.forename: Byung-Soo
authors.initials: BS
authors.lastname: Kim
authors.forename: Moon-Bum
authors.initials: MB
authors.lastname: Kim