title: Differential attraction and repulsion of Staphylococcus aureus and Pseudomonas aeruginosa on molecularly smooth titanium films.
abstract: Magnetron sputtering techniques were used to prepare molecularly smooth titanium thin films possessing an average roughness between 0.18 nm and 0.52 nm over 5 μm × 5 μm AFM scanning areas. Films with an average roughness of 0.52 nm or lower were found to restrict the extent of P. aeruginosa cell attachment, with less than 0.5% of all available cells being retained on the surface. The attachment of S. aureus cells was also limited on films with an average surface roughness of 0.52 nm, however they exhibited a remarkable propensity for attachment on the nano-smoother 0.18 nm average surface roughness films, with the attachment density being almost twice as great as that observed on the nano-rougher film. The difference in attachment behaviour can be attributed to the difference in morphology of the rod-shaped P. aeruginosa compared to the spherical S. aureus cells.
authors.affiliation: Faculty of Life and Social Sciences, Swinburne University of Technology, P.O. Box 218, Hawthorn, Victoria, 3122, Australia. eivanova@swin.edu.au
authors.forename: Elena P
authors.initials: EP
authors.lastname: Ivanova
authors.forename: Vi Khanh
authors.initials: VK
authors.lastname: Truong
authors.forename: Hayden K
authors.initials: HK
authors.lastname: Webb
authors.forename: Vladimir A
authors.initials: VA
authors.lastname: Baulin
authors.forename: James Y
authors.initials: JY
authors.lastname: Wang
authors.forename: Narges
authors.initials: N
authors.lastname: Mohammodi
authors.forename: Feng
authors.initials: F
authors.lastname: Wang
authors.forename: Christopher
authors.initials: C
authors.lastname: Fluke
authors.forename: Russell J
authors.initials: RJ
authors.lastname: Crawford
mesh_terms: D001422:Bacterial Adhesion / Q000502:physiology; D020099:Coated Materials, Biocompatible; D018625:Microscopy, Atomic Force; D008855:Microscopy, Electron, Scanning; D036103:Nanotechnology; D011550:Pseudomonas aeruginosa / Q000502:physiology*; D013211:Staphylococcus aureus / Q000502:physiology*; D013499:Surface Properties; D014025:Titanium
chemical_list: D020099:Coated Materials, Biocompatible; D014025:Titanium