title: Adhesion and activation molecules expressed by human natural killer cells.
abstract: Our study concerns the expression and the regulation of adhesion and activation receptors on human NK cells. In particular we provide evidence on: a) the expression on fresh human NK cells of VLA-4, VLA-5 and VLA-6, extracellular matrix (ECM) receptors of integrin family capable of mediating their adhesion to FN and LM; b) the role of PKC on the regulation of CD16, a differentiation antigen associated with FcγR type III expressed by all NK cells, which mediate ADCC activity and trigger lymphokine production.
authors.affiliation: Dipartimento di Medicina Sperimentale, Universita' di Roma "La Sapienza", Rome, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Santoni
authors.forename: A
authors.initials: A
authors.lastname: Gismondi
authors.forename: R
authors.initials: R
authors.lastname: Paolini
authors.forename: A
authors.initials: A
authors.lastname: Procopio
authors.forename: S
authors.initials: S
authors.lastname: Morrone
authors.forename: F
authors.initials: F
authors.lastname: Mainiero
authors.forename: G
authors.initials: G
authors.lastname: Santoni
authors.forename: M
authors.initials: M
authors.lastname: Piccoli
authors.forename: L
authors.initials: L
authors.lastname: Frati