title: Transversus abdominis plane block reduces postoperative pain intensity and analgesic consumption in elective cesarean delivery under general anesthesia.
abstract: OBJECTIVE
  It is reported that following abdominal surgery, transversus abdominis plane (TAP) block can reduce postoperative pain. The primary outcome of this study was the evaluation of the efficacy of TAP block on pain intensity following cesarean delivery with Pfannenstiel incision.
  
  
  METHODS
  Fifty pregnant women were randomized blindly to receive either a TAP block with 15 ml 0.25% bupivacaine in both sides (group T, n = 25) or no blockade (group C, n = 25) at the end of the surgery, which was performed with a Pfannenstiel incision under general anesthesia. The pain intensity in the patients was assessed by a blinded investigator at the time of discharge from recovery and at 6, 12, and 24 h postoperatively, with a visual analogue scale (VAS) for pain.
  
  
  RESULTS
  The women in the TAP block group had significantly lower VAS pain scores at rest and during coughing and consumed significantly less tramadol than the women in group C [50 mg (0-150) vs. 250 mg (0-400), P = 0.001]. There was a significantly longer time to the first request for analgesic in the TAP block group [210 min (0-300) vs. 30 min (10-180) in group C, P = 0.0001].
  
  
  CONCLUSIONS
  Two-sided TAP block with 0.25% bupivacaine in parturients who undergo cesarean section with a Pfannenstiel incision under general anesthesia can decrease postoperative pain and analgesic consumption. The time to the first analgesic rescue was longer in the parturients who received the TAP block.
authors.affiliation: Department of Obstetrics and Gynecology, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Laleh
authors.initials: L
authors.lastname: Eslamian
authors.forename: Zorvan
authors.initials: Z
authors.lastname: Jalili
authors.forename: Ashraf
authors.initials: A
authors.lastname: Jamal
authors.forename: Vajiheh
authors.initials: V
authors.lastname: Marsoosi
authors.forename: Ali
authors.initials: A
authors.lastname: Movafegh
mesh_terms: D000009:Abdominal Muscles / Q000294:innervation; D000328:Adult; D000701:Analgesics, Opioid / Q000008:administration & dosage*; D000768:Anesthesia, General; D000773:Anesthesia, Obstetrical; D002585:Cesarean Section; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D009407:Nerve Block / Q000379:methods*; D010147:Pain Measurement; D010149:Postoperative Pain / Q000517:prevention & control*; D011247:Pregnancy; D014147:Tramadol / Q000008:administration & dosage*
chemical_list: D000701:Analgesics, Opioid; D014147:Tramadol