title: [Prognostic factors of colorectal cancer lung metastases].
abstract: BACKGROUND
  Colorectal cancer is the third most common neoplasia and the second cause of death due to cancer in developed countries. Approximately 10% of patients with this diagnosis develop lung metastases, although only 2-4% of them have lung metastases as the only extension location.
  
  
  OBJECTIVE
  To study the prognostic factors of colorectal cancer lung metastases.
  
  
  METHODS
  A retrospective observational study was conducted on 30 patients with colorectal cancer lung metastases who were operated on in our hospital between January 2003 and December 2007.
  
  
  RESULTS
  Of the 30 patients who received surgery, 19 were males (63%) and 11 were female (37%), with a mean age of 63.37 years (range 35-82 years). The mean overall survival was 36.64 months (range 18.58-54.70 months). A total of 13 pre-, intra-, and postoperative parameters were used in the statistical analysis. In the univariate analysis, the number of metastases greater than 3 (P=.051), whether they were bilateral (P=.001), or bilobar (P<.001), were statistically significant factors of a poor prognosis. In the multivariate analysis, only being bilobar was shown to be a statistically significant factor of a poor prognosis (P=.005).
  
  
  CONCLUSIONS
  In our patient series affected by colorectal carcinoma lung metastases, the number of metastases greater than three, whether they are bilobar and bilateral, are factors of a poor prognosis. These factors should be taken into account in the follow-up of these patients, although prospective studies with a larger number of patients are required to confirm these findings.
authors.affiliation: Servicio de Cirugía Torácica, Hospital de la Santa Creu i Sant Pau (Unidad docente de la Universidad autónoma de Barcelona [UAB]), Mancomunidad, Hospital Universitario Mutua Terrassa-Hospital de la Santa Creu i Sant Pau-Hospital de Mar (HUMT-HSCSP-HM), Barcelona, España. tempelakius@gmail.com
authors.forename: Núria
authors.initials: N
authors.lastname: Prenafeta Claramunt
authors.forename: Vicenç Artigas
authors.initials: VA
authors.lastname: Raventós
authors.forename: Guillermo Gómez
authors.initials: GG
authors.lastname: Sebastián
authors.forename: Elisabeth Martínez
authors.initials: EM
authors.lastname: Téllez
authors.forename: Josep Belda
authors.initials: JB
authors.lastname: Sanchís
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015179:Colorectal Neoplasms / Q000401:mortality / Q000473:pathology*; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000401:mortality / Q000556:secondary*; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012189:Retrospective Studies; D015996:Survival Rate