title: Predicting pH at birth in pregnancies with abnormal pulsatility index and positive end-diastolic velocity in the umbilical artery.
abstract: OBJECTIVE
  To identify potential associations between fetal surveillance tests and acidosis at birth in pregnancies with abnormal but positive end-diastolic velocity in the umbilical artery.
  
  
  METHODS
  A prospective case-control study [group 1: pH < 7.2; group 2: pH ≥ 7.2] including 46 fetuses with abnormal but positive end-diastolic velocity in the umbilical artery was conducted between February 2007 and March 2009. Outcome variables were evaluated by univariate analysis and compared between the two groups. Clinically relevant and statistically significant variables were analyzed by logistic regression.
  
  
  RESULTS
  Abnormal nonstress test, presence of deceleration, and absent fetal breathing movements were statistically significant. Logistic regression analysis revealed that fetal heart rate (FHR) deceleration in the nonstress test is the only predictor of fetal acidosis at birth (p = 0.024; OR = 8.2; 95%CI: 1.2-52).
  
  
  CONCLUSIONS
  In fetuses with positive end-diastolic flow velocity, acute variables of the antenatal surveillance tests are correlated with acidosis at birth and FHR deceleration in the nonstress test is the only predictor of fetal acidosis.
authors.affiliation: Department of Obstetrics and Gynecology, University of São Paulo, São Paulo, Brazil. renatalsp@ig.com.br
authors.forename: Renata
authors.initials: R
authors.lastname: Lopes Ribeiro
authors.forename: Rossana
authors.initials: R
authors.lastname: Pulcineli Vieira Francisco
authors.forename: Seizo
authors.initials: S
authors.lastname: Miyadahira
authors.forename: Marcelo
authors.initials: M
authors.lastname: Zugaib
mesh_terms: D000138:Acidosis / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000503:physiopathology; D000293:Adolescent; D000328:Adult; D001783:Blood Flow Velocity / Q000502:physiology*; D016022:Case-Control Studies; D003971:Diastole; D005260:Female; D005315:Fetal Diseases / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000503:physiopathology; D006305:Health Status Indicators; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000175:diagnosis / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D015997:Neonatal Screening / Q000379:methods*; D036801:Parturition / Q000097:blood / Q000378:metabolism / Q000502:physiology; D011247:Pregnancy; D011379:Prognosis; D011673:Pulsatile Flow / Q000502:physiology*; D014463:Ultrasonography; D014469:Umbilical Arteries / Q000000981:diagnostic imaging / Q000503:physiopathology*; D055815:Young Adult