title: Management of giant anal condyloma by wide local excision and anoplasty.
abstract: OBJECTIVE
  Treatment of giant condyloma acuminatum, is controversial, especially in human immunodeficiency virus (HIV)-positive patients, owing to concern over wound healing, complications, risk of progression to carcinoma and a high recurrence rate. The aim of this study was to evaluate the outcome after extensive local excision with V-Y anoplasty.
  
  
  METHODS
  Nine patients were identified from a prospective database, six of whom were HIV positive. All patients had a giant perianal condyloma acuminatum extending into the anal canal and perianal region, which required wide excision with V-Y reconstruction. Postoperative complications, recurrence and continence were all determined.
  
  
  RESULTS
  Nine patients were included (eight men, median age 40 years), six seropositive for HIV infection. A bilateral V-Y anoplasty was performed in six patients, and unilateral in two. There were no postoperative infections, graft failures or flap necrosis. The mean follow-up was 92 (2-137) months. One patient developed local recurrence treated with excision under local anaesthesia.
  
  
  CONCLUSIONS
  Extensive local surgery of giant perianal condyloma with anoplastic reconstruction gives good results even in HIV-positive patients.
authors.affiliation: Department of Surgery, Hospital Arnau de Vilanova of Valencia, Valencia, Spain.
authors.forename: N
authors.initials: N
authors.lastname: Uribe
authors.forename: C
authors.initials: C
authors.lastname: Rueda
authors.forename: M
authors.initials: M
authors.lastname: López
authors.forename: Z
authors.initials: Z
authors.lastname: Balciscueta
authors.forename: M C
authors.initials: MC
authors.lastname: Martín
authors.forename: J J
authors.initials: JJ
authors.lastname: Terrádez
authors.forename: J
authors.initials: J
authors.lastname: Flores
mesh_terms: D000328:Adult; D001003:Anal Canal / Q000503:physiopathology / Q000601:surgery*; D062688:Buschke-Lowenstein Tumor / Q000503:physiopathology / Q000601:surgery*; D013505:Digestive System Surgical Procedures / Q000379:methods*; D005260:Female; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D011446:Prospective Studies; D019651:Plastic Surgery Procedures / Q000009:adverse effects / Q000379:methods; D012008:Recurrence; D016896:Treatment Outcome