title: [Clinico-epidemiological analysis of choroidal melanoma in Split Area, Croatia].
abstract: Choroidal melanoma is the most common primary intraocular malignant tumour in adults. The aim of the study was to examine epidemiological characteristics of choroidal melanoma in Split-Dalmatia County from 1990 to 2009. In this retrospective study, data on 46 patients from medical documentation of the University Department of Ophthalmology, Split University Hospital Center, were analyzed. According to 2001 census, the Split-Dalmatia County population was 467,676 inhabitants. The incidence of choroidal melanoma was 0.49 per 100,000 inhabitants, which is somewhere in the middle of the incidence between south and north Europe. Choroidal melanoma most commonly appeared in the 7th decade of life. The average dimensions of choroidal melanoma (basis x height) were 13.4 x 8.0 mm. Histopathologic findings according to Callender classification showed the following types of melanoma: epithelioid cell type 8%, spindle cell type 40%, and mixed type 52%. The most common forms of therapy were enucleation 47.8% and brachytherapy 28.3%, which means that patients presented relatively late when choroidal melanoma advanced in size. The Split-Dalmatia County has 1/10 of the Croatian population, so it could be supposed that approximately 25 new cases of malignant melanoma of the choroid are discovered annually in Croatia. For early detection of the disease, regular and complete checkups are necessary, especially in presbyopic population. Study results enabled better evaluation of the disease and better planning of ophthalmologic service in the treatment of this serious eye disease.
authors.affiliation: Medicinski fakultet Sveucilista u Splitu, Split, Hrvatska. mcpero@xnet.hr
authors.forename: Petar
authors.initials: P
authors.lastname: Ivanisević
authors.forename: Lovro
authors.initials: L
authors.lastname: Bojić
authors.forename: Snjezana
authors.initials: S
authors.lastname: Tomić
authors.forename: Kajo
authors.initials: K
authors.lastname: Bucan
authors.forename: Milan
authors.initials: M
authors.lastname: Ivanisević
authors.forename: Mladen
authors.initials: M
authors.lastname: Lesin
authors.forename: Ivna
authors.initials: I
authors.lastname: Plestina-Borjan
authors.forename: Robert
authors.initials: R
authors.lastname: Stanić
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002830:Choroid Neoplasms / Q000175:diagnosis* / Q000453:epidemiology / Q000628:therapy; D017523:Croatia / Q000453:epidemiology; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008545:Melanoma / Q000175:diagnosis* / Q000453:epidemiology / Q000628:therapy; D008875:Middle Aged