title: Clostridium perfringens infection complicating periprosthetic fracture fixation about the hip: successful treatment with early aggressive debridement.
abstract: Periprosthetic fracture and infection are both challenges following hip arthroplasty. We report the case of an 87 year old female who underwent open reduction and internal fixation of a periprosthetic femoral fracture. Her post-operative course was complicated by infection with Clostridium perfringens. Early aggressive antibiotic treatment and surgical debridement were successful, and allowed retention of the original components.
authors.affiliation: Department of Orthopaedic Surgery, Cork University Hospital, Cork, Ireland. joseph.f.baker@gmail.com
authors.forename: Joseph F
authors.initials: JF
authors.lastname: Baker
authors.forename: Mihai H
authors.initials: MH
authors.lastname: Vioreanu
authors.forename: James A
authors.initials: JA
authors.lastname: Harty
mesh_terms: D000284:Administration, Oral; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D003015:Clostridium Infections / Q000150:complications / Q000473:pathology* / Q000628:therapy; D003016:Clostridium perfringens / Q000302:isolation & purification; D003646:Debridement; D005260:Female; D006620:Hip Fractures / Q000382:microbiology* / Q000473:pathology / Q000601:surgery; D006621:Hip Joint / Q000382:microbiology / Q000473:pathology / Q000601:surgery; D006801:Humans; D007275:Injections, Intravenous; D008795:Metronidazole / Q000627:therapeutic use; D010397:Penicillanic Acid / Q000031:analogs & derivatives / Q000627:therapeutic use; D057068:Periprosthetic Fractures / Q000382:microbiology* / Q000473:pathology / Q000601:surgery; D016459:Prosthesis-Related Infections / Q000382:microbiology* / Q000473:pathology / Q000628:therapy; D000078142:Tazobactam; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D008795:Metronidazole; D010397:Penicillanic Acid; D000078142:Tazobactam