title: Miniaturization in biotechnology: speeding up the development of bioprocesses.
abstract: The use of miniaturized devices for fastening bioprocess development, even up to production scale, has expanded rapidly, a feature clearly noticeable in recent years. This matter was reviewed in a recent past, but several developments have occurred since. These will be addressed in the present work, which will provide some insight on the use of microfluidic /microstructured reactors and of micro-scale downstream processing as well, therefore broadening the scope of the review.
authors.affiliation: Department of Bioengineering, Instituto Superior Tecnico, Universidade Tecnica de Lisboa, Portugal. pedro.fernandes@ist.utl.pt
authors.forename: Pedro
authors.initials: P
authors.lastname: Fernandes
authors.forename: Filipe
authors.initials: F
authors.lastname: Carvalho
authors.forename: Marco P C
authors.initials: MP
authors.lastname: Marques
mesh_terms: D001331:Automation; D055162:Biocatalysis; D019149:Bioreactors; D001709:Biotechnology / Q000295:instrumentation / Q000379:methods*; D046210:Microfluidic Analytical Techniques / Q000295:instrumentation / Q000379:methods; D008904:Miniaturization; D010330:Patents as Topic