title: Antebrachial chondrodysplasia in New Zealand white rabbits (Oryctolagus cuniculus).
abstract: Rabbits obtained from a South African rabbit breeder exhibited deformities of the distal forelimbs. The clinical, radiological and histological presentation of mid-antebrachial valgus formation (a.k.a distal foreleg curvature) in these rabbits was consistent with an autosomal recessive trait associated with a chondrodystrophic lesion of the distal ulna epiphysis 1st described in the 1960s. The impact this might have on South African farming enterprises and laboratory facilities has not been established, but the heritability and welfare implications of this condition make it a concern. Mildly affected animals can adapt to the deformity with some housing adjustments, but severely affected animals may require humane euthanasia.
authors.affiliation: University of Pretoria Biomedical Research Centre, Private Bag X04, Onderstepoort 0110, South Africa. tamsyn.pulker@up.ac.za
authors.forename: T
authors.initials: T
authors.lastname: Pulker
authors.forename: A
authors.initials: A
authors.lastname: Carstens
authors.forename: J
authors.initials: J
authors.lastname: Williams
mesh_terms: D000818:Animals; D001848:Bone Diseases, Developmental / Q000175:diagnosis / Q000235:genetics / Q000662:veterinary*; D001947:Breeding; D005260:Female; D005808:Genes, Recessive; D020022:Genetic Predisposition to Disease; D017880:Limb Deformities, Congenital / Q000175:diagnosis / Q000235:genetics / Q000662:veterinary*; D011817:Rabbits / Q000235:genetics