title: Mitotically active xanthogranuloma:  a case report with review of the literature.
abstract: Juvenile xanthogranuloma is a benign histiocytic lesion that displays different histologic patterns. The classic form consists of a proliferation of foamy histiocytes admixed with numerous multinucleated Touton-type giant cells, lymphocytes, and eosinophils. Mitotic figures are rare or even absent. Apart from this classic form, a nonlipidized form showing a diffuse infiltrate of nonfoamy histiocytes with or without rare Touton-type giant cells is described. The mitotic activity is somewhat higher than in the classic form. We describe here an unusual case, occurring in a 71-year-old man, characterized by a very high mitotic index (22 mitotic figures per 10 high-power fields).
authors.affiliation: Department of Pathology, Institut de Pathologie et Génétique, Gosselies, Charleroi, Belgium. placide.ngendahayo@ipg.be
authors.forename: Placide
authors.initials: P
authors.lastname: Ngendahayo
authors.forename: Nicolas
authors.initials: N
authors.lastname: de Saint Aubain
mesh_terms: D000368:Aged; D015703:Antigens, CD / Q000378:metabolism; D015415:Biomarkers / Q000378:metabolism; D006801:Humans; D007866:Leg; D008297:Male; D008940:Mitotic Index; D035583:Rare Diseases / Q000473:pathology; D014972:Xanthogranuloma, Juvenile / Q000378:metabolism / Q000473:pathology* / Q000601:surgery
chemical_list: D015703:Antigens, CD; D015415:Biomarkers