title: [Infectious endocarditis in intensive care patients].
abstract: Infectious endocarditis is a rare disease with high mortality. Epidemiological changes in recent years, the emergence of new risk factors, and the increasing use of intravasal prosthetic materials has led to changes in not only the clinical appearance of this disease but also in its diagnosis and treatment. Early diagnosis of infectious endocarditis is crucial. However, the often unspecific symptoms and the changes in its epidemiologic profile pose a challenge for the treating physician. This is especially true since the incidence of hospital-acquired, "nosocomial" cases of infectious endocarditis is increasing and often affects severely ill patients in intensive care units (ICU). There are diagnostic and therapeutic algorithms to guide the physician from an early diagnosis to an adequate treatment of the disease. In some critically ill patients, only surgery in combination with antimicrobial treatment may lead to complete eradication of the infectious disease. This review aims to subsume the guidelines, paying special attention to aspects that are important for intensive care and emergency doctors.
authors.affiliation: Universitätsklinik und Poliklinik für Innere Medizin III (Kardiologie/Angiologie/Internistische Intensivmedizin/Geriatrie/Sportmedizin), Department für Innere Medizin, Universitätsklinikum Halle (Saale) der Martin-Luther-Universität Halle/Wittenberg, Ernst-Grube-Str. 40, 06097, Halle (Saale), Deutschland. sebastian.dietz@medizin.uni-halle.de
authors.forename: S
authors.initials: S
authors.lastname: Dietz
authors.forename: H
authors.initials: H
authors.lastname: Lemm
authors.forename: U
authors.initials: U
authors.lastname: Raaz
authors.forename: K
authors.initials: K
authors.lastname: Werdan
authors.forename: M
authors.initials: M
authors.lastname: Buerke
mesh_terms: D000465:Algorithms; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D016470:Bacteremia / Q000175:diagnosis / Q000401:mortality / Q000628:therapy; D003299:Cooperative Behavior; D003428:Cross Infection / Q000175:diagnosis* / Q000401:mortality / Q000628:therapy; D004452:Echocardiography; D004617:Embolism / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D004697:Endocarditis, Bacterial / Q000175:diagnosis* / Q000401:mortality / Q000628:therapy; D019983:Guideline Adherence; D006350:Heart Valve Prosthesis; D006801:Humans; D007362:Intensive Care Units; D033183:Interdisciplinary Communication; D008826:Microbial Sensitivity Tests; D011157:Population Dynamics; D011379:Prognosis; D012307:Risk Factors; D055502:Secondary Prevention; D012680:Sensitivity and Specificity; D016019:Survival Analysis
chemical_list: D000900:Anti-Bacterial Agents