title: Orofacial pain models and behavior assessment.
abstract: Orofacial pain remains an understudied area in pain research given that most attention has been focused on the spinal system. In this chapter, animal models of neuropathic and inflammatory orofacial pain are presented. Four different types of pain behavior tests are then described for assessing evoked and spontaneous pain behavior in addition to conditional reward behavior. The use of a combination of different pain models and behavior assessments is needed to aid in understanding the mechanisms contributing to orofacial pain in humans for developing effective therapy.
authors.affiliation: Department of Anatomy, University of California San Francisco, San Francisco, CA, USA.
authors.forename: Timothy K Y
authors.initials: TK
authors.lastname: Kaan
authors.forename: Peter T
authors.initials: PT
authors.lastname: Ohara
authors.forename: Luc
authors.initials: L
authors.lastname: Jasmin
mesh_terms: D000818:Animals; D001522:Behavior, Animal; D005157:Facial Pain / Q000473:pathology* / Q000503:physiopathology / Q000523:psychology; D023421:Models, Animal; D010147:Pain Measurement / Q000379:methods*; D051381:Rats