title: Growth and metabolism of human tumor kidney cells on galactose and glucose.
abstract: The culture kinetics of human tumor kidney cells (TCL 598) grown on microcarriers are compared with media initially supplemented with either glucose alone or a mixture of galactose and glucose. Growth rates and maximal cell densities are similar, but cellular death is much slower in galactose than in glucose. Galactose is metabolized at a much slower specific rate than glucose. Cells grown in the galactose medium show a different pattern of lactate and pyruvate metabolism compared to cells grown in the glucose medium. Growth with galactose also favours oxidation of glutamine to alanine.
authors.affiliation: Institut National Polytechnique de Lorraine, Laboratoire des Sciences du Génie Chimique, CNRS-ENSIC-ENSAIA, 1, rue Grandville, BP 451, 54001, Nancy Cedex, France.
authors.forename: A
authors.initials: A
authors.lastname: Wagner
authors.forename: A
authors.initials: A
authors.lastname: Marc
authors.forename: J M
authors.initials: JM
authors.lastname: Engasser
authors.forename: A
authors.initials: A
authors.lastname: Einsele