title: [The possibility of the fertility preservation in young cancer patients based on practice of oncofertility treatment].
abstract: Young female cancer patients face various problems, including a decrease in their quality of life(QOL)due to early menopause or loss of fertility after remission. Chemotherapy and radiotherapy can cause loss of reproductive function in young women due to adverse effects such as ovarian failure. The frequency of ovarian failure depends on the age of the patient, the anticancer agents used, and the dose of each agent. In these patients, improvement of the post-treatment QOL and fertility preservation can be achieved by measures such as protection of ovarian function against the effects of anticancer agents. Ovum freezing or fertilized egg freezing are also becoming fertility preservation methods for these patients. However, ovarian hyperstimulation to obtain ova is time consuming and sometimes considered taboo depending on the type of cancer. A self solution to problems occurring frequently at the same time is demanded from the patient, and the patient is forced to deal with too many choices in too little time. It is often less than one month until the cancer treatment begins after an underlying disease is diagnosed, since chemotherapy cannot be delayed. In these cases, cryopreservation of ovarian tissue is currently proposed for fertility preservation. In this manuscript, I will discuss a topic about fertility preservation in young cancer survivors including recent knowledge regarding cryopreservation of ovarian tissue.
authors.affiliation: Dept. of Obstetrics and Gynecology, St. Marianna University School of Medicine, Japan.
authors.forename: Nao
authors.initials: N
authors.lastname: Suzuki
authors.forename: Nobuhito
authors.initials: N
authors.lastname: Yoshioka
authors.forename: Yodo
authors.initials: Y
authors.lastname: Sugishita
authors.forename: Seido
authors.initials: S
authors.lastname: Takae
authors.forename: Yuki
authors.initials: Y
authors.lastname: Horage
authors.forename: Suguru
authors.initials: S
authors.lastname: Igarashi
authors.forename: Shu
authors.initials: S
authors.lastname: Hashimoto
authors.forename: Yoshiharu
authors.initials: Y
authors.lastname: Morimoto
authors.forename: Bunpei
authors.initials: B
authors.lastname: Ishizuka
mesh_terms: D000328:Adult; D000970:Antineoplastic Agents / Q000009:adverse effects*; D059247:Fertility Preservation; D006801:Humans; D009369:Neoplasms / Q000628:therapy; D011788:Quality of Life
chemical_list: D000970:Antineoplastic Agents