title: New triterpenoid saponins from Patrinia scabiosifolia.
abstract: Phytochemical investigation of methanol extract from the whole plants of Patrinia scabiosifolia Fisch. resulted in the isolation of three new triterpenoid saponins (1-3) along with twelve known triterpenoids (4-15). The structures of the new compounds were established as 11α, 12α-epoxy-3-O-β-D-xylopyranosyl-olean-28, 13β-olide (1), 11α, 12α-epoxy-3-O-β-D-xylopyranosyl-(1 → 3)-α-L-rhamnopyranosyl-(1 → 2)-β-D-xylopyranosyl-olean-28, 13β-olide (2), and 3-O-β-D-xylopyranosyl-(1 → 3)-α-L-rhamnopyranosyl-(1 → 2)-β-D-xylopyranosyl oleanolic acid 28-O-β-D-glucopyranoside (3) on the basis of various spectroscopic analyses (including different 1D and 2D NMR spectroscopies and high-resolution electrospray ionization mass spectrometry) and chemical evidences.
authors.affiliation: College of Pharmaceutical Science, Soochow University, Suzhou 215123, China.
authors.forename: Liang
authors.initials: L
authors.lastname: Gao
authors.forename: Lin
authors.initials: L
authors.lastname: Zhang
authors.forename: Li-Ming
authors.initials: LM
authors.lastname: Wang
authors.forename: Jiang-Yun
authors.initials: JY
authors.lastname: Liu
authors.forename: Pei-Lie
authors.initials: PL
authors.lastname: Cai
authors.forename: Shi-Lin
authors.initials: SL
authors.lastname: Yang
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004354:Drug Screening Assays, Antitumor; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D056945:Hep G2 Cells; D006801:Humans; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D032405:Patrinia / Q000737:chemistry*; D012503:Saponins / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D013237:Stereoisomerism; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: C571638:11alpha,12alpha-epoxy-3-O-beta-D-xylopyranosyl-(1-3)-alpha-L-rhamnopyranosyl-(1-2)-beta-D-xylopyranosyl-olean-28,13beta-olide; C571637:11alpha,12alpha-epoxy-3-O-beta-D-xylopyranosyl-olean-28,13beta-olide; C571639:3-O-D-xylopyranosyl-(1-3)-alpha-L-rhamnopyranosyl-(1-2)-beta-D-xylopyranosyl oleanolic acid 28-O-beta-D-glucopyranoside; D000972:Antineoplastic Agents, Phytogenic; D004365:Drugs, Chinese Herbal; D012503:Saponins; D014315:Triterpenes