title: Prognostic value of preoperative coronary computed tomography angiography in patients treated by orthotopic liver transplantation.
abstract: OBJECTIVE
  The aim of this study was to assess the feasibility of 64-slice coronary computed tomography (CT) angiography in patients treated by orthotopic liver transplantation, and to compare prognostic values of CT angiography and dobutamine stress echocardiography in the same population.
  
  
  METHODS
  Eighty-two consecutive patients, without known coronary artery disease, who underwent orthotopic liver transplantation, were included in this study. A CT angiography was performed along with usual explorations including dobutamine stress echography. A one-year minimal follow-up was performed to seek cardiac events.
  
  
  RESULTS
  Fifty-two (65.8%) patients underwent a CT angiography. Thirty-seven (71%) were totally normal or showed nonobstructive coronary plaque, six (12%) showed at least one obstructive coronary plaque greater than 50%. Nine (17%) of the examined patients had at least one nonassessable segment. A total of six (7.6%) major cardiac events occurred in a mean-time follow-up of 17.8 ± 12.7 months.
  
  
  CONCLUSIONS
  CT angiography that is normal or with a nonobstructive coronary plaque has a negative predicting value of 95% [0.82-0.99] for major cardiac adverse events, and of 100% [0.91-1] for clinical coronary events in patients undergoing orthotopic liver transplantation. The prognostic value of CT angiography was comparable with that of dobutamine stress echography.
authors.affiliation: Department of Radiology, Timone Hospital, Marseille Cedex, France. pierre.cassagneau@ap-hm.fr
authors.forename: Pierre
authors.initials: P
authors.lastname: Cassagneau
authors.forename: Alexis
authors.initials: A
authors.lastname: Jacquier
authors.forename: Roch
authors.initials: R
authors.lastname: Giorgi
authors.forename: Nicolas
authors.initials: N
authors.lastname: Amabile
authors.forename: Jean-Yves
authors.initials: JY
authors.lastname: Gaubert
authors.forename: Fréderic
authors.initials: F
authors.lastname: Cohen
authors.forename: Cyril
authors.initials: C
authors.lastname: Muller
authors.forename: Marianne
authors.initials: M
authors.lastname: Jolibert
authors.forename: Guillaume
authors.initials: G
authors.lastname: Louis
authors.forename: Arthur
authors.initials: A
authors.lastname: Varoquaux
authors.forename: Vincent
authors.initials: V
authors.lastname: Vidal
authors.forename: Jean-Michel
authors.initials: JM
authors.lastname: Bartoli
authors.forename: Guy
authors.initials: G
authors.lastname: Moulin
mesh_terms: D000328:Adult; D017023:Coronary Angiography / Q000379:methods*; D003324:Coronary Artery Disease / Q000150:complications* / Q000000981:diagnostic imaging; D025401:Echocardiography, Stress; D005240:Feasibility Studies; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008107:Liver Diseases / Q000150:complications / Q000601:surgery*; D016031:Liver Transplantation; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D057234:Preoperative Period; D011379:Prognosis; D014057:Tomography, X-Ray Computed / Q000379:methods*