title: Glioblastoma associated with intratumoral abscess formation. Case report.
abstract: A 45-year-old man presented with a rare case of glioblastoma associated with intratumoral abscess formation manifesting as headache and vomiting after an appendectomy. Computed tomography and magnetic resonance imaging demonstrated a ring-enhanced lesion mimicking malignant glioma. Craniotomy and tumor removal were performed. Abscess formation within the intra-axial tumor was found intraoperatively. Histological examination revealed glioblastoma with abscess, and the etiological agent was anaerobic Gram-negative bacilli. The suspected route of microbial migration and colonization in this tumor was bacteremia from appendicitis.
authors.affiliation: Department of Neurosurgery, Tokai University School of Medicine, Isehara, Kanagawa. tsugu@is.icc.u-tokai.ac.jp
authors.forename: Atsushi
authors.initials: A
authors.lastname: Tsugu
authors.forename: Takahiro
authors.initials: T
authors.lastname: Osada
authors.forename: Jun
authors.initials: J
authors.lastname: Nishiyama
authors.forename: Mitsunori
authors.initials: M
authors.lastname: Matsumae
mesh_terms: D001062:Appendectomy / Q000009:adverse effects / Q000379:methods; D001064:Appendicitis / Q000150:complications / Q000382:microbiology; D001922:Brain Abscess / Q000382:microbiology / Q000473:pathology* / Q000601:surgery; D001932:Brain Neoplasms / Q000150:complications / Q000473:pathology* / Q000601:surgery; D017809:Fatal Outcome; D005909:Glioblastoma / Q000150:complications / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000382:microbiology* / Q000503:physiopathology