title: Severe coinfection of melioidosis and dengue fever in Northeastern Brazil: first case report.
abstract: This report focuses on a fatality involving severe dengue fever and melioidosis in a 28-year-old truck driver residing in Pacoti in northeastern Brazil. He exhibited long-term respiratory symptoms (48 days) and went through a wide-ranging clinical investigation at three hospitals, after initial clinical diagnoses of pneumonia, visceral leishmaniasis, tuberculosis, and fungal sepsis. After death, Burkholderia pseudomallei was isolated in a culture of ascitic fluid. Dengue virus type 1 was detected by polymerase chain reaction in cerebrospinal fluid (CSF); this infection was the cause of death. This description reinforces the need to consider melioidosis among the reported differential diagnoses of community-acquired infections where both melioidosis and dengue fever are endemic.
authors.affiliation: Ambulatório de Doenças Infecciosas, Hospital Geral de Fortaleza, Fortaleza, CE.
authors.forename: Rafael Nogueira
authors.initials: RN
authors.lastname: Macedo
authors.forename: Felipe Araujo
authors.initials: FA
authors.lastname: Rocha
authors.forename: Dionne Bezerra
authors.initials: DB
authors.lastname: Rolim
authors.forename: Dina Cortez Lima Feitosa
authors.initials: DC
authors.lastname: Vilar
authors.forename: Fernanda Montenegro de Carvalho
authors.initials: FM
authors.lastname: Araújo
authors.forename: Nélia Nogueira
authors.initials: NN
authors.lastname: Vieira
authors.forename: Juliana Rodrigues
authors.initials: JR
authors.lastname: Teixeira
authors.forename: Maíza Colares
authors.initials: MC
authors.lastname: Carvalho
authors.forename: Francisco George Magalhães
authors.initials: FG
authors.lastname: Oliveira
authors.forename: Luciano Pamplona de Góes
authors.initials: LP
authors.lastname: Cavalcanti
mesh_terms: D000328:Adult; D016957:Burkholderia pseudomallei / Q000302:isolation & purification; D060085:Coinfection / Q000175:diagnosis* / Q000382:microbiology / Q000821:virology; D003715:Dengue / Q000150:complications / Q000175:diagnosis*; D003716:Dengue Virus / Q000302:isolation & purification; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D008554:Melioidosis / Q000150:complications / Q000175:diagnosis*