title: [Analysis of the genetic background and mechanisms of dissemination of resistance to tetracycline of the Polish population of Campylobacter strains isolated in Poland in years 2007-2008].
abstract: In Poland, constant rise of number of Campylobacter strains resistant to tetracycline is observed in Poland. Analysis of the resistant strains showed their strong diversity, including both the different levels of resistance to this drug, large differences in the sequence of the resistant gene tetO, and diverse phylogenetic origin. The study also confirmed the important role of horizontal spread of resistance which, in the event of such a large diversity of resistant strains, can cause further very rapid escalation of resistance of Campylobacter to tetracycline.
authors.affiliation: Zakład Bakteriologii Narodowego Instytutu Zdrowia Publicznego-Państwowego Zakładu Higieny w Warszawie. twolkowicz@pzh.gov.pl
authors.forename: Tomasz
authors.initials: T
authors.lastname: Wołkowicz
authors.forename: Jolanta
authors.initials: J
authors.lastname: Szych
authors.forename: Sebastian
authors.initials: S
authors.lastname: Wardak
mesh_terms: D001426:Bacterial Proteins / Q000235:genetics; D002167:Campylobacter / Q000145:classification / Q000187:drug effects* / Q000235:genetics / Q000302:isolation & purification; D008826:Microbial Sensitivity Tests; D013045:Species Specificity; D013753:Tetracycline Resistance / Q000235:genetics*
chemical_list: D001426:Bacterial Proteins