title: Urinary iodine and sodium status of urban Korean subjects: a pilot study.
abstract: OBJECTIVE
  We estimated iodine status of Korean population by determining the concentration of spot urinary iodine (UI) with a reliable method based on the Sandell-Kolthoff reaction.
  
  
  METHODS
  A total of 540 urine samples from apparently healthy subjects were collected, and UI, urinary sodium (UNa), and urinary creatinine (UCr) were determined from those samples and analyzed with age.
  
  
  RESULTS
  There were significant decreases in either UI (P<0.0001), UI/UCr ratio (P=0.0001), UNa (P<0.0001), or UNa/Cr ratio (P=0.0001) in younger subjects than older ones. The median value of UI was 267.6 μg/L, but the median UI of the younger group (191.8 μg/L) was significantly decreased compared to that of the older group (383.9 μg/L).
  
  
  CONCLUSIONS
  This study showed that the median of UI in Korean urban population was in a more than adequate iodine nutritional state, but UI was significantly different between the younger age group and the older age group.
authors.affiliation: Department of Laboratory Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.
authors.forename: Jonghyeon
authors.initials: J
authors.lastname: Choi
authors.forename: Hyo-Sik
authors.initials: HS
authors.lastname: Kim
authors.forename: Duck Jin
authors.initials: DJ
authors.lastname: Hong
authors.forename: Hyunsun
authors.initials: H
authors.lastname: Lim
authors.forename: Jeong-Ho
authors.initials: JH
authors.lastname: Kim
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D015415:Biomarkers / Q000652:urine; D003404:Creatinine / Q000652:urine*; D005247:Feeding Behavior; D005260:Female; D006801:Humans; D007455:Iodine / Q000652:urine*; D008297:Male; D008875:Middle Aged; D010865:Pilot Projects; D056910:Republic of Korea; D012680:Sensitivity and Specificity; D012964:Sodium / Q000652:urine*; D016482:Urinalysis; D055815:Young Adult
chemical_list: D015415:Biomarkers; D007455:Iodine; D012964:Sodium; D003404:Creatinine