title: Compartment syndrome in all four extremities: a rare case associated with systemic capillary leak syndrome.
abstract: While isolated limb injuries often lead to suspicion for and treatment of compartment syndrome, multi-limb compartment syndrome induced by a systemic disease is a rare entity, in which lack of immediate diagnosis can have catastrophic consequences to the patient. We present a patient with idiopathic systemic capillary leak syndrome (SCLS) resulting in compartment syndrome in all four extremities. Treatment required bilateral hand, forearm, calf, and thigh fasciotomies. Presenting symptoms included pain in all four extremities, malaise, and confusion. Laboratory data included polycythemia, hypoalbuminemia, leukocytosis, and elevated creatinine, but not a monoclonal spike on serum electrophoresis as is common in SCLS. Thus, when faced with clinical evidence of multiple extremity compartment syndrome, the surgeon should consider systemic disorders, such as SCLS, and aggressively treat the compartment syndrome as well as the underlying disease.
authors.affiliation: Division of Plastic Surgery, Baylor College of Medicine, Clinical Care Center, 6701 Fannin, CC 610, Houston, TX 77030 USA.
authors.forename: Rodger H
authors.initials: RH
authors.lastname: Brown
authors.forename: Cara
authors.initials: C
authors.lastname: Downey
authors.forename: Shayan
authors.initials: S
authors.lastname: Izaddoost