title: [Effects of stimulation of nervous fibres upon contractile activity of the tracheobronchial lymphatic node capsules' smooth muscles].
abstract: The contractile activity of smooth muscle of tracheobronchial lymph nodes' capsules was recorded in vitro. The field electric stimulation (0.5 ms pulses, 55 V nominal, 4 min trains at frequencies 0.5, 1, 2, 4, 8, 16 and 32 Hz) of strips from lymph node produced a frequency-dependent increase in baseline tension and frequency of phase contractions. Evoked contractions were significantly (about 80%) reduced by tetrodotoxin (1 x 10(-6) M). The blockage of M-cholinoreceptors with atropine (1 x 10(-6) M) did not affect the field-evoked responses. Contractile field-evoked effects were significantly reduced by the phentolamine (1 x 10(-7)-1 x 10(-6) M) but not completely. Field-evoked contractions were slightly affected by the propranolol (1 x 10(-7)-1 x 10(-6) M). We conclude that the contractile activity of bovine tracheobronchial lymph node capsular smooth muscle is modulated by excitatory adrenergic nerves.
authors.forename: G I
authors.initials: GI
authors.lastname: Lobov
authors.forename: M N
authors.initials: MN
authors.lastname: Pan'kova
mesh_terms: D000818:Animals; D001285:Atropine / Q000494:pharmacology; D002417:Cattle; D004558:Electric Stimulation / Q000379:methods; D008198:Lymph Nodes / Q000187:drug effects / Q000294:innervation*; D009043:Motor Activity / Q000187:drug effects; D018727:Muscarinic Antagonists / Q000494:pharmacology; D009119:Muscle Contraction / Q000187:drug effects / Q000502:physiology*; D009130:Muscle, Smooth / Q000187:drug effects / Q000294:innervation / Q000502:physiology*; D010646:Phentolamine / Q000494:pharmacology; D011433:Propranolol / Q000494:pharmacology; D011976:Receptors, Muscarinic / Q000502:physiology; D013779:Tetrodotoxin / Q000494:pharmacology; D014132:Trachea / Q000187:drug effects / Q000502:physiology*
chemical_list: D018727:Muscarinic Antagonists; D011976:Receptors, Muscarinic; D013779:Tetrodotoxin; D001285:Atropine; D011433:Propranolol; D010646:Phentolamine