title: Mortality from cancer and other causes in an Italian cohort of male rubber tire workers.
abstract: OBJECTIVE
  To investigate mortality among workers of an Italian rubber tire factory employed between 1954 and 2008.
  
  
  METHODS
  This cohort study included 6246 men, totaling 190,512 man-years of observation. Employment data were obtained from personnel records, whereas vital status and causes of death were ascertained from local authorities. We computed standardized mortality ratios (SMRs) using national and regional death certification rates.
  
  
  RESULTS
  Mortality was significantly lower than expected for all cancers (SMR = 79) and all causes (SMR = 85). The SMRs were 99 for cancer of stomach, 78 for lung, 121 for urinary bladder, 116 for lymphoma, and 89 for leukemia, none being significant. Decreased mortality emerged for cancers of the oral cavity and pharynx (SMR = 45), esophagus (SMR = 29), colorectum (SMR = 71), liver (SMR = 57), and kidney (SMR = 33).
  
  
  CONCLUSIONS
  This study shows no excess cancer risk among male rubber tire workers employed after 1954.
authors.affiliation: Dipartimento di Traumatologia, Ortopedia e Medicina del Lavoro, Università degli Studi di Torino, Turin, Italy.
authors.forename: Enrico
authors.initials: E
authors.lastname: Pira
authors.forename: Claudio
authors.initials: C
authors.lastname: Pelucchi
authors.forename: Canzio
authors.initials: C
authors.lastname: Romano
authors.forename: Marco
authors.initials: M
authors.lastname: Manzari
authors.forename: Eva
authors.initials: E
authors.lastname: Negri
authors.forename: Carlo
authors.initials: C
authors.lastname: La Vecchia
mesh_terms: D002423:Cause of Death; D002561:Cerebrovascular Disorders / Q000401:mortality; D015331:Cohort Studies; D006801:Humans; D007558:Italy / Q000453:epidemiology; D007938:Leukemia / Q000401:mortality; D008175:Lung Neoplasms / Q000401:mortality; D008223:Lymphoma / Q000401:mortality; D008297:Male; D008420:Manufactured Materials; D017202:Myocardial Ischemia / Q000401:mortality; D009369:Neoplasms / Q000401:mortality*; D009784:Occupational Diseases / Q000401:mortality*; D029424:Pulmonary Disease, Chronic Obstructive / Q000401:mortality; D012408:Rubber; D013274:Stomach Neoplasms / Q000401:mortality; D001749:Urinary Bladder Neoplasms / Q000401:mortality
chemical_list: D012408:Rubber