title: Sebaceous metaplasia in a canine mammary gland non-infiltrative carcinoma with myoepithelial component.
abstract: Sebaceous metaplasia in canine mammary tumors is a rare condition with only 1 case documented. The current study describes a case of sebaceous metaplasia in a mammary gland carcinoma of an 8-year-old intact, nulliparous female Poodle dog with a subcutaneous tumor located in the left fifth mammary gland. The lesion measured 0.7 cm × 0.5 cm × 0.6 cm in diameter, was firm, circumscribed, painless, non-haired, and non-ulcerated, and did not adhere to deep tissues. The cut surface was non-lobulated, non-encapsulated, whitish to gray, and opaque. Histological evaluation revealed 3 different populations of cells: the first was composed of columnar to cuboidal malignant epithelial cells arranged in intraductal papillary projections, the second of myoepithelial cells associated with a myxoid stroma, and the third presenting sebaceous metaplasia similar to those previously described in both human and veterinary medicine.
authors.affiliation: Departamento de Patologia, Faculdade de Medicina de Botucatu, Univ. Estadual Paulista, Botucatu, São Paulo, Brazil.
authors.forename: Fabrizio
authors.initials: F
authors.lastname: Grandi
authors.forename: Marcia M
authors.initials: MM
authors.lastname: Colodel
authors.forename: Rafael M
authors.initials: RM
authors.lastname: Rocha
authors.forename: Julio L
authors.initials: JL
authors.lastname: Sequeira
mesh_terms: D000818:Animals; D002277:Carcinoma / Q000473:pathology / Q000601:surgery / Q000662:veterinary*; D004283:Dog Diseases / Q000473:pathology* / Q000601:surgery; D004285:Dogs; D005260:Female; D015674:Mammary Neoplasms, Animal / Q000473:pathology* / Q000601:surgery; D009208:Myoepithelioma / Q000473:pathology / Q000601:surgery / Q000662:veterinary*; D012626:Sebaceous Gland Neoplasms / Q000473:pathology / Q000601:surgery / Q000662:veterinary*