title: Large middle cerebral artery and panhemispheric infarction.
abstract: Large middle cerebral artery (MCA) and panhemispheric stroke represent a minority of cerebral ischemic events, yet they are responsible for a disproportionate share of morbidity and mortality. Malignant infarction with formation of cerebral edema is a common cause for secondary neurologic deterioration. Despite intensive medical and surgical care, prognosis is often poor and mortality may be as high as 60-80%. Surgical intervention can reduce that mortality compared to medical therapy alone, but necessitates a careful exploration of patient characteristics for acceptable outcomes.
authors.affiliation: Dipartimento di Scienze Mediche e Chirurgiche, Clinica Neurologica, Università degli Studi di Brescia, Brescia, Italy. ale_pezzini@hotmail.com
authors.forename: Alessia
authors.initials: A
authors.lastname: Giossi
authors.forename: Irene
authors.initials: I
authors.lastname: Volonghi
authors.forename: Elisabetta
authors.initials: E
authors.lastname: Del Zotto
authors.forename: Paolo
authors.initials: P
authors.lastname: Costa
authors.forename: Alessandro
authors.initials: A
authors.lastname: Padovani
authors.forename: Alessandro
authors.initials: A
authors.lastname: Pezzini
mesh_terms: D006801:Humans; D020244:Infarction, Middle Cerebral Artery; D011379:Prognosis; D012307:Risk Factors; D020521:Stroke / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology