title: [Experimental study of the effect of detoxification with enterosorbents on the function of irradiated myocardium].
abstract: Increase in intoxication products, such as medium size peptides, indole and myoglobin, in urine was observed in Wistar rats after exposure of their chest to gamma-radiation at a dose of 6 Gy (dose rate 4 Gy/min). The rats exhibited moderate ischemic ECG. Administration of enterosorbents, such as Smekta and Clay of Kaluga deposit, to the irradiated rats resulted in the decrease of the toxicant content in the animals and the recovery of the cardiac function on the 28th day. These sorbents had practically a similar efficacy.
authors.forename: V S
authors.initials: VS
authors.lastname: Nesterenko
authors.forename: E M
authors.initials: EM
authors.lastname: Iatsenko
authors.forename: N P
authors.initials: NP
authors.lastname: Savina
authors.forename: M V
authors.initials: MV
authors.lastname: Filimonova
authors.forename: I L
authors.initials: IL
authors.lastname: Khakau
authors.forename: L A
authors.initials: LA
authors.lastname: Moiseeva
authors.forename: A G
authors.initials: AG
authors.lastname: KonoplIannikov
mesh_terms: D000538:Aluminum Silicates / Q000008:administration & dosage*; D000818:Animals; D000077215:Clay; D004562:Electrocardiography; D016061:Enterosorption / Q000379:methods*; D005720:Gamma Rays; D006321:Heart / Q000187:drug effects* / Q000503:physiopathology* / Q000528:radiation effects; D007211:Indoles / Q000652:urine; D008297:Male; D017202:Myocardial Ischemia / Q000188:drug therapy / Q000503:physiopathology / Q000652:urine; D009206:Myocardium; D009211:Myoglobin / Q000032:analysis; D011833:Radiation Injuries, Experimental / Q000188:drug therapy* / Q000503:physiopathology / Q000652:urine; D051381:Rats; D017208:Rats, Wistar; D017640:Silicates / Q000008:administration & dosage*
chemical_list: D000538:Aluminum Silicates; D007211:Indoles; D009211:Myoglobin; D017640:Silicates; C016752:smecta; C030374:indole; D000077215:Clay