title: [Combined inhalation and epidural anesthesia, during aortocoronary bypass surgery on beating heart].
abstract: Aim of study is to compare efficiency and safety of different methods of combined inhalational and epidural anesthesia during aortocoronary bypass surgery on beating heart.
  
  
  METHODS
  40 patients suffering from coronary heart disease were included in randomized study. Two methods of combined inhalational and epidural anesthesia were compared. The first group of 22 patients were administrated extended-release epidural anesthesia with Ropivacaine 0.3% in upper thoracic region and Sevoflurane as a volatile agent. Second group of 18 patients were administrated Isoflurane and epidural anesthesia. Monitoring: (Harvard standard of monitoring), BIS, invasive monitoring of hemodynamic, the dose of anesthetic gas, internal medical audit. Result of the study showed that all patient had same duration of surgery, level of unconsciousness (BIS 40-45%) dose of valiant anesthetic agents less than 1 MAC, same dose of Ropivacaine, minimal dose of opioids, quantity and quality of intravenous infusion therapy and same amount of vasopressors. It was discovered that Sevoflurane had influenced hemodynamic less than Isoflurane. The results of internal retrospective medical study showed safety of both methods of anesthesia. Sevoflurane allowed fast postoperative recovery on 1,74 times ,early extubation in theater on 1,64 times. Both methods of combined anesthesia epidural and inhalational presented good results and can be performed in coronary bypass surgery but for fast-track surgery and anesthesia use of Sevoflurane is better.
mesh_terms: D000577:Amides / Q000008:administration & dosage / Q000009:adverse effects; D000767:Anesthesia, Epidural / Q000009:adverse effects / Q000379:methods*; D000769:Anesthesia, Inhalation / Q000009:adverse effects / Q000379:methods*; D019162:Anesthetics, Combined / Q000008:administration & dosage* / Q000009:adverse effects; D018685:Anesthetics, Inhalation / Q000008:administration & dosage / Q000009:adverse effects; D000779:Anesthetics, Local / Q000008:administration & dosage / Q000009:adverse effects; D056805:Consciousness Monitors; D001026:Coronary Artery Bypass / Q000379:methods*; D006439:Hemodynamics; D006801:Humans; D007530:Isoflurane / Q000008:administration & dosage / Q000009:adverse effects; D008738:Methyl Ethers / Q000008:administration & dosage / Q000009:adverse effects; D008875:Middle Aged; D000077212:Ropivacaine; D000077149:Sevoflurane; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D000577:Amides; D019162:Anesthetics, Combined; D018685:Anesthetics, Inhalation; D000779:Anesthetics, Local; D008738:Methyl Ethers; D000077149:Sevoflurane; D000077212:Ropivacaine; D007530:Isoflurane