title: [Changes in organ donor epidemiology and new strategies for kidney preservation].
abstract: Changes in the epidemiology of brain death are leading the transplant community to use more marginal grafts from so-called extended criteria donors. Current preservation techniques, while simple, are no longer adequate for these organs, which harbor chronic lesions making them very sensitive to ischemia-reperfusion injury. New preservation solutions are needed, along with machine perfusion techniques (dynamic preservation) and normothermic preservation phases.
authors.affiliation: Urologie, GH Pitié Salpêtriere, Faculté de Médecine, Université Paris VI, Inserm U 927--Poitiers, Plateforme IBISA INRA Surgères. Groupe de recherche Flirt. benoit.barrou@psl.aphp.fr
authors.forename: Benoît
authors.initials: B
authors.lastname: Barrou
mesh_terms: D001926:Brain Death; D006801:Humans; D016030:Kidney Transplantation; D009926:Organ Preservation / Q000379:methods*; D019188:Organ Preservation Solutions; D015427:Reperfusion Injury / Q000517:prevention & control
chemical_list: D019188:Organ Preservation Solutions