title: Antibiotic-impregnated beads for the treatment of aortic graft infection.
abstract: Infection of a prosthetic graft after replacement of the ascending aorta is an uncommon but life-threatening complication of surgery. We report the use of antibiotic-impregnated calcium sulfate beads in a patient with ascending aortic graft infection to provide localized, high-dose therapy to the infected region. Perigraft placement of antibiotic beads provides an alternative method for the treatment of aortic graft infection.
authors.affiliation: Division of Cardiovascular and Thoracic Surgery, Intermountain Medical Center, Murray, Utah 84157, USA.
authors.forename: Aaron H
authors.initials: AH
authors.lastname: Healy
authors.forename: Bruce B
authors.initials: BB
authors.lastname: Reid
authors.forename: Bryce D
authors.initials: BD
authors.lastname: Allred
authors.forename: John R
authors.initials: JR
authors.lastname: Doty
mesh_terms: D000368:Aged; D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D001011:Aorta / Q000601:surgery*; D001807:Blood Vessel Prosthesis / Q000009:adverse effects*; D004337:Drug Carriers; D006801:Humans; D008297:Male; D008863:Microspheres; D016459:Prosthesis-Related Infections / Q000188:drug therapy*; D013203:Staphylococcal Infections / Q000188:drug therapy*; D014031:Tobramycin / Q000008:administration & dosage*; D014640:Vancomycin / Q000008:administration & dosage*
chemical_list: D000900:Anti-Bacterial Agents; D004337:Drug Carriers; D014640:Vancomycin; D014031:Tobramycin