title: Interactions between intracellular free Ca2+ and cyclic AMP in neuroendocrine cells.
abstract: Calcium ions and cyclic adenosine monophosphate (cAMP) are virtually ubiquitous intracellular signaling molecules in mammalian cells. This paper will focus on the cross-talk between Ca(2+) and cAMP mobilizing signaling pathways and summarize the underlying molecular mechanisms. Subsequently, workings of adenohypophyseal corticotrope cells will be reviewed to highlight the physiological relevance of a Ca(2+) cAMP interactions in neuroendocrinology.
authors.affiliation: Division of Preclinical Research, EGIS Pharmaceuticals PLC, Hungary. franzantoni@gmail.com
authors.forename: Ferenc A
authors.initials: FA
authors.lastname: Antoni
mesh_terms: D000324:Adrenocorticotropic Hormone / Q000378:metabolism*; D000818:Animals; D002118:Calcium / Q000737:chemistry / Q000378:metabolism*; D020013:Calcium Signaling; D052680:Corticotrophs / Q000502:physiology*; D000242:Cyclic AMP / Q000378:metabolism*; D006801:Humans; D015290:Second Messenger Systems / Q000502:physiology
chemical_list: D000324:Adrenocorticotropic Hormone; D000242:Cyclic AMP; D002118:Calcium