title: "My parents died of myocardial infarction: is that my destiny?".
abstract: This article presents an overview of clinical and molecular genetics of myocardial infarction (MI). Discussion includes the partial overlapping of risk factors for myocardial infarction and atherosclerosis, the impact of a positive family history on the risk of MI, the "familial" nongenetic, environmental factors, the inherited risk associated with the low-dose input of many genes, and a simple approach to stratify the individual risk in genetic counseling.
authors.affiliation: Centre for Inherited Cardiovascular Diseases, Foundation IRCCS Policlinico San Matteo, P.le Golgi n. 19 27100 Pavia, Italy.
authors.forename: Nupoor
authors.initials: N
authors.lastname: Narula
authors.forename: Claudio
authors.initials: C
authors.lastname: Rapezzi
authors.forename: Luigi
authors.initials: L
authors.lastname: Tavazzi
authors.forename: Eloisa
authors.initials: E
authors.lastname: Arbustini
mesh_terms: D050197:Atherosclerosis / Q000453:epidemiology / Q000235:genetics / Q000523:psychology; D015987:Effect Modifier, Epidemiologic; D005192:Family Health; D059647:Gene-Environment Interaction; D005817:Genetic Counseling; D020022:Genetic Predisposition to Disease; D055106:Genome-Wide Association Study; D006801:Humans; D020412:Multifactorial Inheritance; D009203:Myocardial Infarction / Q000453:epidemiology / Q000235:genetics / Q000523:psychology; D018570:Risk Assessment; D012307:Risk Factors; D040242:Risk Reduction Behavior