title: Congenital smooth muscle hamartoma of the palpebral conjunctiva.
abstract: Smooth muscle hamartoma is defined as a disorganized focus or an overgrowth of mature smooth muscle, generally with low capacity of autonomous growth and benign behavior. The implicated tissues are mature and proliferate in a disorganized fashion. A healthy 5-day-old Mexican boy was referred to the authors' hospital in México city for evaluation of a "cystic" lesion of the right eye that had been noted since birth. The pregnancy and delivery were unremarkable. On physical examination, there was a reddish-pink soft lesion with a tender "cystic" appearance, which was probably emerging from the upper eyelid conjunctiva, which measured 2.7 cm in its widest diameter and transilluminated. Ultrasound imaging revealed an anterior "cystic" lesion with normally formed phakic eye. An excisional biopsy was performed, and the lesion was dissected from the upper tarsal subconjunctival space. Subsequent histologic and immunohistochemical findings were consistent with the diagnosis of congenital smooth muscle hamartoma (CSMH) of the tarsal conjunctiva. The authors' research revealed that only one case of CSMH localized in the conjunctiva (Roper GJ, Smith MS, Lueder GT. Congenital smooth muscle hamartoma of the conjunctival fornix. Am J Ophthalmol. 1999;128:643-4) has been reported to date in the literature. To the best of the authors' knowledge, this current case would be the second case reported of CSMH in this anatomic location. Therefore, the authors' recommendation is to include CSMH in the differential diagnosis of a cystic mass that presents in the fornix and palpebral conjunctiva.
authors.affiliation: Department of Oculoplastics and Orbit, Asociación para Evitar la Ceguera en México, Institucion de Asistencia Privada Hospital, Dr. Luis Sánchez Bulnes, San Lucas Coyoacán, DF México. moraevelyn@hotmail.com
authors.forename: L Evelyn
authors.initials: LE
authors.lastname: Mora
authors.forename: Abelardo A
authors.initials: AA
authors.lastname: Rodríguez-Reyes
authors.forename: Ana M
authors.initials: AM
authors.lastname: Vera
authors.forename: Rosa Isela
authors.initials: RI
authors.lastname: Rubio
authors.forename: Mariana
authors.initials: M
authors.lastname: Mayorquín-Ruiz
authors.forename: Guillermo
authors.initials: G
authors.lastname: Salcedo
mesh_terms: D003230:Conjunctival Neoplasms / Q000151:congenital* / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D005143:Eyelids; D006222:Hamartoma / Q000151:congenital* / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D019042:Muscle Neoplasms / Q000151:congenital* / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D009130:Muscle, Smooth / Q000473:pathology*; D014463:Ultrasonography