title: NDM-1 producing Acinetobacter baumannii isolated from a patient repatriated to the Czech Republic from Egypt, July 2011.
abstract: We describe the isolation of an NDM-1-producing Acinetobacter baumannii in a Czech patient repatriated in July 2011 from Egypt. The infection spread to another patient on the same ward. Both isolates showed the same resistance pattern and were susceptible only to colistin. They had an identical PFGE pattern and belonged to the same sequence type ST 1. Sequencing of the blaNDM gene identified the NDM-1 variant of the carbapenemase, surrounded by two copies of insertion sequence ISAba125.
authors.affiliation: Department of Microbiology, Faculty of Medicine in Plzeň, Charles University in Prague, Plzeň, Czech Republic. Jaroslav.Hrabak@lfp.cuni.cz
authors.forename: J
authors.initials: J
authors.lastname: Hrabák
authors.forename: M
authors.initials: M
authors.lastname: Stolbová
authors.forename: V
authors.initials: V
authors.lastname: Studentová
authors.forename: M
authors.initials: M
authors.lastname: Fridrichová
authors.forename: E
authors.initials: E
authors.lastname: Chudáčková
authors.forename: H
authors.initials: H
authors.lastname: Zemlickova
mesh_terms: D000151:Acinetobacter Infections / Q000175:diagnosis / Q000188:drug therapy / Q000635:transmission; D040981:Acinetobacter baumannii / Q000201:enzymology / Q000235:genetics* / Q000302:isolation & purification; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001426:Bacterial Proteins / Q000096:biosynthesis; D015373:Bacterial Typing Techniques; D018153:Czech Republic; D004534:Egypt; D016521:Electrophoresis, Gel, Pulsed-Field; D005260:Female; D005784:Gene Amplification; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D008969:Molecular Sequence Data; D053717:Pneumonia, Ventilator-Associated / Q000382:microbiology*; D016133:Polymerase Chain Reaction; D014195:Travel; D018440:beta-Lactam Resistance; D001618:beta-Lactamases / Q000096:biosynthesis / Q000235:genetics*
chemical_list: D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; D001618:beta-Lactamases; C552864:beta-lactamase NDM-1; C063912:carbapenemase