title: Cu-promoted [2 + 2] cycloaddition of 1,4-bisallenes.
abstract: The thermal reaction of 1,4-bisallenes with the aid of Cu salt/amine significantly suppressed the formal [3,3] sigmatropic rearrangement resulting in the highly selective formation of the bicyclo[4.2.0]octadiene framework. This reaction could be applied to the one-pot synthesis of bicyclo[4.2.0]octadienes from 1,5-hexadiynes via the Crabbé homologation.
authors.affiliation: Division of Pharmaceutical Sciences, Graduate School of Natural Science and Technology, Kanazawa University, Kakuma-machi, Kanazawa 920-1192, Japan. kitagaki@p.kanazawa-u.ac.jp
authors.forename: Shinji
authors.initials: S
authors.lastname: Kitagaki
authors.forename: Mikihito
authors.initials: M
authors.lastname: Kajita
authors.forename: Syu
authors.initials: S
authors.lastname: Narita
authors.forename: Chisato
authors.initials: C
authors.lastname: Mukai
mesh_terms: D000466:Alkadienes / Q000138:chemical synthesis* / Q000737:chemistry; D000480:Alkynes / Q000737:chemistry*; D000588:Amines / Q000737:chemistry; D001643:Bridged Bicyclo Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D003500:Cyclization; D015394:Molecular Structure; D012492:Salts / Q000737:chemistry
chemical_list: D000466:Alkadienes; D000480:Alkynes; D000588:Amines; D001643:Bridged Bicyclo Compounds; D012492:Salts; C025947:propadiene; D003300:Copper