title: Outcomes of critically ill gynecological cancer patients admitted to intensive care unit.
abstract: OBJECTIVE
  To assess the characteristics of critically ill patients with gynecological cancer, and to evaluate their prognosis.
  
  
  METHODS
  Fifty-two critically ill patients with gynecological cancer admitted to intensive care unit (ICU) were included. Univariate and multivariate logistic regressions were used to identify factors associated with hospital mortality.
  
  
  RESULTS
  Thirty-five patients (67.3%) had carcinoma of the cervix uteri and 11 (21.2%) had ovarian cancer. The mortality rate in the ICU was 17.3% (9 of 52) and hospital mortality rate were 23%(12 of 52). In the multivariate analysis, independent prognostic factors for hospital mortality were vasopressor use (odds ratio [OR] = 8.60, 95% confidence interval [CI] 2.05-36; P = .03) and the Acute Physiology and Chronic Health Evaluation (APACHE) II score (OR = 1.43, 95% CI 1.01-2.09; P = .048).
  
  
  CONCLUSIONS
  The independent prognostic factors for hospital mortality were the need for vasopressors and the APACHE II score.
authors.affiliation: Department of Critical Care Medicine, Instituto Nacional de Cancerología and Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico. snamendys@incan.edu.mx
authors.forename: Silvio A
authors.initials: SA
authors.lastname: Namendys-Silva
authors.forename: María O
authors.initials: MO
authors.lastname: González-Herrera
authors.forename: Julia
authors.initials: J
authors.lastname: Texcocano-Becerra
authors.forename: Angel
authors.initials: A
authors.lastname: Herrera-Gómez
mesh_terms: D018806:APACHE; D000328:Adult; D000368:Aged; D016638:Critical Illness / Q000453:epidemiology / Q000401:mortality*; D005260:Female; D005833:Genital Neoplasms, Female / Q000453:epidemiology / Q000401:mortality*; D017052:Hospital Mortality; D006801:Humans; D007362:Intensive Care Units / Q000706:statistics & numerical data*; D007902:Length of Stay; D008875:Middle Aged; D011379:Prognosis; D012307:Risk Factors; D015996:Survival Rate; D016896:Treatment Outcome