title: Soybean Knowledge Base (SoyKB): a web resource for soybean translational genomics.
abstract: BACKGROUND
  Soybean Knowledge Base (SoyKB) is a comprehensive all-inclusive web resource for soybean translational genomics. SoyKB is designed to handle the management and integration of soybean genomics, transcriptomics, proteomics and metabolomics data along with annotation of gene function and biological pathway. It contains information on four entities, namely genes, microRNAs, metabolites and single nucleotide polymorphisms (SNPs).
  
  
  METHODS
  SoyKB has many useful tools such as Affymetrix probe ID search, gene family search, multiple gene/metabolite search supporting co-expression analysis, and protein 3D structure viewer as well as download and upload capacity for experimental data and annotations. It has four tiers of registration, which control different levels of access to public and private data. It allows users of certain levels to share their expertise by adding comments to the data. It has a user-friendly web interface together with genome browser and pathway viewer, which display data in an intuitive manner to the soybean researchers, producers and consumers.
  
  
  CONCLUSIONS
  SoyKB addresses the increasing need of the soybean research community to have a one-stop-shop functional and translational omics web resource for information retrieval and analysis in a user-friendly way. SoyKB can be publicly accessed at http://soykb.org/.
authors.affiliation: Department of Computer Science, University of Missouri, Columbia, MO 65211, USA.
authors.forename: Trupti
authors.initials: T
authors.lastname: Joshi
authors.forename: Kapil
authors.initials: K
authors.lastname: Patil
authors.forename: Michael R
authors.initials: MR
authors.lastname: Fitzpatrick
authors.forename: Levi D
authors.initials: LD
authors.lastname: Franklin
authors.forename: Qiuming
authors.initials: Q
authors.lastname: Yao
authors.forename: Jeffrey R
authors.initials: JR
authors.lastname: Cook
authors.forename: Zheng
authors.initials: Z
authors.lastname: Wang
authors.forename: Marc
authors.initials: M
authors.lastname: Libault
authors.forename: Laurent
authors.initials: L
authors.lastname: Brechenmacher
authors.forename: Babu
authors.initials: B
authors.lastname: Valliyodan
authors.forename: Xiaolei
authors.initials: X
authors.lastname: Wu
authors.forename: Jianlin
authors.initials: J
authors.lastname: Cheng
authors.forename: Gary
authors.initials: G
authors.lastname: Stacey
authors.forename: Henry T
authors.initials: HT
authors.lastname: Nguyen
authors.forename: Dong
authors.initials: D
authors.lastname: Xu
mesh_terms: D019295:Computational Biology / Q000379:methods; D018745:Genome, Plant / Q000235:genetics*; D023281:Genomics / Q000379:methods*; D012984:Software; D013025:Glycine max / Q000235:genetics*