title: Transient coordinated activity within the developing brain's default network.
abstract: The concept of a brain default network postulates that specific brain regions are more active when a person is engaged in introspective mental activity. Transient functional coordination between groups of neurons is thought to be necessary for information processing. Since children develop introspection as they mature, regions of the default network may establish increasing functional coordination with age, resulting in fewer fluctuations in synchronization patterns. We investigated the transient coordinated activity in regions of the default network in seventeen children aged 11 months to 17 years of age using EEG recordings while subjects were resting quietly with eyes closed. The temporal and spatial fluctuations in the phase synchrony patterns were estimated across sites associated with the default network pattern and compared to other regions. Lower variability of the spatio-temporal patterns of phase synchronization associated with the default network was observed in the older group as compared to the younger group. This indicates that functional coordination increases among regions of the default network as children develop.
authors.forename: Vera
authors.initials: V
authors.lastname: Nenadovic
authors.forename: Luis
authors.initials: L
authors.lastname: Garcia Dominguez
authors.forename: Marc D
authors.initials: MD
authors.lastname: Lewis
authors.forename: O Carter
authors.initials: OC
authors.lastname: Snead
authors.forename: Andriy
authors.initials: A
authors.lastname: Gorin
authors.forename: Jose Luis
authors.initials: JL
authors.lastname: Perez Velazquez