title: The use of porcine acellular dermal matrix in silicone implant-based breast reconstruction.
abstract: BACKGROUND
  The most frequently occurring long-term complication in implant-based breast reconstruction is fibrotic capsule formation at the recipient site, with concurrent dysesthesia and poor aesthetic results. Using porcine acellular dermal matrix (PADM) as a connective tissue graft material is supposed to improve the quality and quantity of soft tissue in implant-based breast reconstruction. This study investigates the indications for and the results and the costs of using PADM for the correction or prevention of implant-associated breast deformities.
  
  
  METHODS
  This study reviewed a single surgeon's experience in the correction or prevention of implant-associated breast deformities with PADM in breast cancer-related breast reconstruction from 2009 to 2011. A total of 23 patients (27 breasts) were included in the study. The aesthetic outcome, the incidence and the type of complication were analysed. Twenty-three women underwent breast cancer-related breast reconstruction: 19 women underwent single-breast reconstruction and four women underwent bilateral reconstruction.
  
  
  RESULTS
  Of the 23 patients who underwent breast reconstruction, 18 (78%) were "satisfied" with the aesthetic and haptic outcome after implant-based reconstruction with PADM. One patient (one breast) required another breast operation because of ipsilateral breast cancer recurrence during the follow-up period. PADM-assisted implant-based breast reconstruction has a satisfactory safety profile.
  
  
  CONCLUSIONS
  The use of PADM as an interface matrix for implant-based breast reconstruction yielded predictable and acceptable aesthetic and haptic results by preventing capsular contracture, rippling, implant malposition, soft-tissue thinning and failure of the silicone implant-based breast augmentation.
authors.affiliation: Department of Obstetrics and Gynaecology, Ludwig-Maximillians-University Hospital, Munich, Germany. Isabelle.himsl@med.uni-muenchen.de
authors.forename: I
authors.initials: I
authors.lastname: Himsl
authors.forename: V
authors.initials: V
authors.lastname: Drinovac
authors.forename: M
authors.initials: M
authors.lastname: Lenhard
authors.forename: D
authors.initials: D
authors.lastname: Stöckl
authors.forename: T
authors.initials: T
authors.lastname: Weissenbacher
authors.forename: D
authors.initials: D
authors.lastname: Dian
mesh_terms: D000328:Adult; D000368:Aged; D000818:Animals; D001672:Biocompatible Materials; D018427:Breast Implants / Q000009:adverse effects; D001943:Breast Neoplasms / Q000601:surgery; D004954:Esthetics; D005260:Female; D006801:Humans; D016462:Mammaplasty / Q000009:adverse effects / Q000379:methods*; D008408:Mastectomy; D008875:Middle Aged; D017060:Patient Satisfaction; D012828:Silicones; D017768:Skin, Artificial; D013552:Swine; D054457:Tissue Scaffolds; D014110:Touch
chemical_list: D001672:Biocompatible Materials; D012828:Silicones