title: Multiple endocardial neurofibromas in a rosy-billed pochard (Netta peposaca).
abstract: Endocardial neoplasms are uncommon in veterinary species with most cases restricted to endocardial schwannomas in aged rats. A 15-year-old male rosy-billed pochard (Netta peposaca) was diagnosed following necropsy with numerous, proliferative endocardial masses. Histologically, these masses were composed of interlacing streams and bundles of neoplastic spindle cells supported by a fine fibrovascular stroma. Rare areas of cellular and nuclear palisading were present in the nodules. Approximately 60% of the neoplastic cells were strongly positive for S-100, whereas none of the neoplastic cells was positive for desmin, synaptophysin, neurofilament, and glial fibrillary acidic protein. The histologic features coupled with the S-100 immunoreactivity led to a diagnosis of endocardial neurofibroma.
authors.affiliation: Harvard Medical School, New England Regional Primate Research Center, Southborough, MA 01772, USA. Andrew_Miller@hms.harvard.edu
authors.forename: Andrew D
authors.initials: AD
authors.lastname: Miller
authors.forename: Eric J
authors.initials: EJ
authors.lastname: Baitchman
authors.forename: Katherine
authors.initials: K
authors.lastname: Masek-Hammerman
mesh_terms: D000818:Animals; D046090:Anseriformes; D001715:Bird Diseases / Q000473:pathology*; D017809:Fatal Outcome; D006338:Heart Neoplasms / Q000473:pathology / Q000662:veterinary*; D007150:Immunohistochemistry / Q000662:veterinary; D008297:Male; D017253:Neurofibromatoses / Q000473:pathology / Q000662:veterinary*