title: [Application of Y-SNPs in forensic genetics].
abstract: The study presents the results obtained by LightSNiP method with the use of 2 SNPs located on Y chromosome. The purpose of this study was examination of the mixture of the genetic material in the form of male and female blood in different dilutions. The size of available STR-PCR markers is between 100 and 500 bp, which can limit the possibility of DNA mixture analysis, where the amount of male DNA is relatively low or the genetic material is markedly degraded. Selection of appropriate SNPs placed on Y chromosome can provide information that will facilitate interpretation of the female and male DNA mixture. The test was performed on a Light Cycler 2.0, Roche Diagnostic.
authors.affiliation: Z Katedry i Zakładu Medycyny Sadowej Uniwersytetu Medycznego im. Karola Marcinkowskiego w Poznaniu. makoncia@poczta.onet.pl
authors.forename: Monica
authors.initials: M
authors.lastname: Abreu-Głowacka
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Koralewska-Kordel
authors.forename: Eliza
authors.initials: E
authors.lastname: Michalak
authors.forename: Czesław
authors.initials: C
authors.lastname: Zaba
authors.forename: Zygmunt
authors.initials: Z
authors.lastname: Przybylski
mesh_terms: D001801:Blood Stains; D041322:Chromosomes, Human, Y / Q000235:genetics*; D004247:DNA / Q000097:blood; D016172:DNA Fingerprinting / Q000379:methods*; D005260:Female; D053803:Forensic Genetics / Q000379:methods*; D006801:Humans; D008297:Male; D018895:Microsatellite Repeats / Q000235:genetics*; D011044:Poland; D016133:Polymerase Chain Reaction / Q000379:methods; D020641:Polymorphism, Single Nucleotide / Q000235:genetics*; D012680:Sensitivity and Specificity; D020080:Tandem Repeat Sequences / Q000235:genetics*
chemical_list: D004247:DNA