title: Ethnomedicinal knowledge, belief and self-reported practice of local inhabitants on traditional antimalarial plants and phytotherapy.
abstract: BACKGROUND
  This paper reveals the trend of knowledge and practice of traditional antimalarial plants (TAPs) to prevent/treat malaria.
  
  
  METHODS
  Stratified, systematic random sampling was adopted. The ethnomedicinal survey was conducted between January and March 2011 by involving the selected 371 household members on knowledge and practice of TAPs by administering a pre-tested questionnaire.
  
  
  RESULTS
  Overall, 54.4% respondents had adequate awareness and usage custom of TAPs and 16 types of plant have been most commonly known and employed by the respondents to prevent/treat malaria. Leaves (57.2%) were most commonly used plant part to prepare traditional antimalarial phytotherapy remedies. Decoction was one of the most commonly used methods to administer TAPs. The chi-square test result revealed that a significant association is found between the usage custom of traditional antimalarial plants and gender (P-value=0.0282), age (P-value=0.0024), educational status (P-value=0.0295), and monthly income (P-value=0.0001), although not with the ethnicity (P-value=0.7933) of the respondents.
  
  
  CONCLUSIONS
  TAPs usage is an integral part of the tradition and custom of the Ethiopians. However, nearly half of the respondents have had lack of awareness about TAPs and majority of them are reluctant in exercising either due to its ineffectiveness or its bitter taste. Therefore, further laboratory-based research is extremely imperative to identify their antiplasmodial activity and bioactive molecules which could pave the way to formulate the novel affordable as well as accessible potent antimalarials in the near future.
authors.affiliation: Unit of Medical Entomology & Vector Control, Department of Environmental Health Sciences, College of Public Health and Medical Sciences, Jimma University, Jimma, Ethiopia. k karunamoorthi@yahoo.com
authors.forename: Kaliyaperumal
authors.initials: K
authors.lastname: Karunamoorthi
authors.forename: Endrias
authors.initials: E
authors.lastname: Tsehaye
mesh_terms: D000328:Adult; D000962:Antimalarials / Q000302:isolation & purification / Q000627:therapeutic use*; D001364:Awareness; D016009:Chi-Square Distribution; D003430:Cross-Sectional Studies; D003466:Cultural Characteristics; D004522:Educational Status; D005002:Ethiopia; D005260:Female; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D007182:Income; D007407:Interviews as Topic; D008297:Male; D008519:Medicine, Traditional; D008875:Middle Aged; D008517:Phytotherapy; D028321:Plant Preparations / Q000302:isolation & purification / Q000627:therapeutic use*; D010946:Plants, Medicinal; D012737:Sex Factors; D011795:Surveys and Questionnaires; D055815:Young Adult
chemical_list: D000962:Antimalarials; D028321:Plant Preparations