title: Oral health behavior and metabolic syndrome and its components in adults.
abstract: Inflammation has been strongly related to metabolic syndrome (MetS). Periodontal disease is the most common chronic infection in adults. We investigated a cross-sectional (n = 925) and 3-year longitudinal (n = 685) relationship between the daily frequency of toothbrushing and MetS. In the cross-sectional analysis, the prevalence of MetS was 15.7%. After adjustment for potential confounding factors (including all lifestyle factors), the odds ratios (95% confidence interval [CI]) of having MetS in those who brushed 2 times/day and ≥ 3 times/day were 0.71 (0.48-1.05) and 0.47 (0.24-0.92), respectively, as compared with ratios in those with a toothbrushing frequency of ≤ 1 time/day. Increasing toothbrushing frequency tended to relate inversely to hypertriglyceridemia and high-sensitivity C-reactive protein. In the longitudinal analysis, 99 participants were newly diagnosed with MetS. The adjusted odds ratios (95% CI) of the MetS in participants who brushed 2 times/day and ≥ 3 times/day as compared with participants who brushed ≤ 1 time/day were 0.80 (0.49-1.31) and 0.43 (0.19-0.97), respectively. The frequency of toothbrushing was related inversely only to hypertriglyceridemia, consistent with the cross-sectional analysis. This study found that more frequent toothbrushing is related to a lower prevalence and incidence of MetS. These results suggest that more frequent toothbrushing may contribute to the prevention of MetS due to the inflammation/triglyceride pathway.
authors.affiliation: Division of Biomedical Engineering for Health & Welfare, Tohoku University Graduate School of Biomedical Engineering, 2-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Kobayashi
authors.forename: K
authors.initials: K
authors.lastname: Niu
authors.forename: L
authors.initials: L
authors.lastname: Guan
authors.forename: H
authors.initials: H
authors.lastname: Momma
authors.forename: H
authors.initials: H
authors.lastname: Guo
authors.forename: Y
authors.initials: Y
authors.lastname: Cui
authors.forename: R
authors.initials: R
authors.lastname: Nagatomi
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D002097:C-Reactive Protein / Q000032:analysis; D008078:Cholesterol, LDL / Q000097:blood; D055113:Chronic Periodontitis / Q000517:prevention & control; D016001:Confidence Intervals; D003430:Cross-Sectional Studies; D005260:Female; D015438:Health Behavior; D006801:Humans; D015228:Hypertriglyceridemia / Q000097:blood / Q000517:prevention & control; D007564:Japan; D016015:Logistic Models; D008137:Longitudinal Studies; D008297:Male; D024821:Metabolic Syndrome / Q000097:blood / Q000517:prevention & control*; D016017:Odds Ratio; D012307:Risk Factors; D057566:Self Report; D014099:Toothbrushing / Q000523:psychology / Q000706:statistics & numerical data*
chemical_list: D008078:Cholesterol, LDL; D002097:C-Reactive Protein