title: Regional white matter volumes correlate with delay discounting.
abstract: A preference for immediate gratification is a central feature in addictive processes. However, the neural structures underlying reward delay tolerance are still unclear. Healthy participants (n = 121) completed a delay discounting questionnaire assessing the extent to which they prefer smaller immediate rewards to larger delayed reward after undergoing magnetic resonance imaging (MRI) scanning. Whole brain voxel-based morphometric analysis shows that delay discounting severity was negatively correlated with right prefrontal subgyral white matter volume and positively correlated with white matter volume in parahippocampus/hippocampus, after whole brain correction. This study might better our understanding of the neural basis of impulsivity and addiction.
authors.affiliation: Department of Psychology and Center for Studies of Psychological Application, South China Normal University, GuangZhou, GuangDong, China. rongjun.yu@gmail.com
authors.forename: Rongjun
authors.initials: R
authors.lastname: Yu
mesh_terms: D000293:Adolescent; D000328:Adult; D016739:Behavior, Addictive; D001921:Brain / Q000502:physiology*; D001931:Brain Mapping / Q000379:methods*; D005260:Female; D006624:Hippocampus / Q000502:physiology; D006801:Humans; D007175:Impulsive Behavior; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D011795:Surveys and Questionnaires; D013997:Time Factors