title: Trial of experimental toothpastes regarding quality for cleaning dentures.
abstract: The aim of this study was to evaluate the efficacy of experimental toothpastes for removing denture biofilm by means of a randomized crossover trial. Thirty volunteers brushed their dentures using a brush and four pastes: (1) Corega refreshing mint (control), (2) 0.2% chloramine T, (3) 1.0% chloramine T, and (4) 0.01% fluorosurfactant. Each paste was used for 7 days, and participants were randomized to use them according to one of four sequences. Biofilm was disclosed (neutral red) after each period, photographed, and quantified by means of a software program. All experimental toothpastes were similar to the control in terms of posttreatment biofilm coverage.
authors.affiliation: Department of Dental Materials and Prosthodontics, University of Sao Paulo, Riberirao Preto, Brazil.
authors.forename: Ingrid Machado
authors.initials: IM
authors.lastname: de Andrade
authors.forename: Claudia Helena
authors.initials: CH
authors.lastname: Silva-Lovato
authors.forename: Raphael Freitas
authors.initials: RF
authors.lastname: de Souza
authors.forename: Marina Xavier
authors.initials: MX
authors.lastname: Pisani
authors.forename: Kelly Machado
authors.initials: KM
authors.lastname: de Andrade
authors.forename: Helena de Freitas Oliveira
authors.initials: Hde F
authors.lastname: Paranhos
mesh_terms: D000328:Adult; D000891:Anti-Infective Agents, Local / Q000008:administration & dosage / Q000627:therapeutic use; D018441:Biofilms; D002700:Chloramines / Q000008:administration & dosage / Q000627:therapeutic use; D004396:Coloring Agents; D018592:Cross-Over Studies; D003820:Denture Cleansers / Q000627:therapeutic use*; D003778:Dentures / Q000382:microbiology*; D006801:Humans; D009499:Neutral Red; D009930:Organic Chemicals / Q000627:therapeutic use; D013499:Surface Properties; D013501:Surface-Active Agents / Q000627:therapeutic use; D014099:Toothbrushing / Q000295:instrumentation / Q000379:methods; D014100:Toothpastes / Q000627:therapeutic use*; D014105:Tosyl Compounds / Q000008:administration & dosage / Q000627:therapeutic use
chemical_list: D000891:Anti-Infective Agents, Local; D002700:Chloramines; D004396:Coloring Agents; D003820:Denture Cleansers; D009930:Organic Chemicals; D013501:Surface-Active Agents; D014100:Toothpastes; D014105:Tosyl Compounds; C016300:chloramine-T; D009499:Neutral Red; C038646:Zonyl