title: Iron(III) catalysed synthesis of unsymmetrical di and trisubstituted ureas--a variation of classical Ritter reaction.
abstract: An application of the classical Ritter reaction for the synthesis of unsymmetrical di and trisubstituted ureas catalyzed by FeCl(3) is described. The protocol is of significant interest in view of the easy availability of precursors, mild reaction conditions employed and interestingly its applicability for the alkylation of alcohols capable of forming stable carbocationic intermediates even to the sterically hindered moieties.
authors.affiliation: Peptide Research Laboratory, Department of Studies in Chemistry Central College Campus, Dr. B. R. Ambedkar Veedhi, Bangalore University, #109, Bangalore 560 001, India.
authors.forename: Hosamani
authors.initials: H
authors.lastname: Basavaprabhu
authors.forename: Vommina V
authors.initials: VV
authors.lastname: Sureshbabu
mesh_terms: D002384:Catalysis; D007501:Iron / Q000737:chemistry*; D015394:Molecular Structure; D010647:Phenyl Ethers / Q000737:chemistry; D013237:Stereoisomerism; D014508:Urea / Q000138:chemical synthesis*
chemical_list: D010647:Phenyl Ethers; C076624:dibenzyl ether; D014508:Urea; D007501:Iron