title: Dental findings and oral health status in patients with mucopolysaccharidosis: a case series.
abstract: OBJECTIVE
  To present a mucopolysaccharidosis (MPS) case series evaluating oral manifestations (clinical and radiographic), oral health status and discussing its implications.
  
  
  METHODS
  All patients with MPS attending the Genetics clinic/Brazil were evaluated by means of anamnesis, clinical and radiographic examinations.
  
  
  RESULTS
  The final sample consisted of 12 subjects (nine males and three females), with ages ranging from 3-31 years old. Concerning oral health, it was observed high levels of caries and periodontal problems. About oral manifestations, this study clinically observed more cases of delayed tooth eruption, thickness of alveolar process and thick lips. Radiographically, it was observed alterations on condyle, mandibular ramus and joint fossa.
  
  
  CONCLUSIONS
  The dental changes in MPS population are high and consequently it is important to know them for differential diagnoses, early treatment intervention, prevention and education of both patients and parents/caregivers about oral health.
authors.affiliation: Department of Specific Formation, School of Dentistry, Fluminense Federal University, Nova Friburgo, Brazil. liviaazeredo@vm.uff.br
authors.forename: Lívia Azeredo Alves
authors.initials: LA
authors.lastname: Antunes
authors.forename: Ana Paula Barreto
authors.initials: AP
authors.lastname: Nogueira
authors.forename: Glória Fernanda
authors.initials: GF
authors.lastname: Castro
authors.forename: Márcia Gonçalves
authors.initials: MG
authors.lastname: Ribeiro
authors.forename: Ivete Pomarico Ribeiro
authors.initials: IP
authors.lastname: de Souza
mesh_terms: D000293:Adolescent; D000328:Adult; D000539:Alveolar Process / Q000473:pathology; D002648:Child; D002675:Child, Preschool; D003731:Dental Caries / Q000150:complications*; D005260:Female; D006801:Humans; D008046:Lip / Q000473:pathology; D008297:Male; D008310:Malocclusion / Q000150:complications*; D009083:Mucopolysaccharidoses / Q000150:complications*; D009909:Oral Health; D010510:Periodontal Diseases / Q000150:complications*; D014078:Tooth Eruption; D055815:Young Adult