title: [New knowledge of spasticity and its treatment].
abstract: Spasticity is a frequently used diagnosis, and anti-spastic medication is used widespread. In this systematic review article we highlight difficulties in diagnosing spasticity correctly and thus limit the value of the diagnosis in ensuring the best possible treatment. We review recent neuroscience research and conclude that it is necessary to develop better tools for clinical diagnosis of spasticity in order to avoid potential malpractice and to limit treatment with anti-spastic drugs for patients with documented increased reflex-mediated muscle tone as their main annoyance.
authors.affiliation: Center for Rett syndrom, Kennedy Centret, Gammel Landevej 7, 2600 Glostrup, Denmark. jlorentzen@ifi.ku.dk
authors.forename: Jakob
authors.initials: J
authors.lastname: Lorentzen
authors.forename: Maria
authors.initials: M
authors.lastname: Willerslev-Olsen
authors.forename: Clarissa
authors.initials: C
authors.lastname: Crone
authors.forename: Thomas
authors.initials: T
authors.lastname: Sinkjær
authors.forename: Jens B
authors.initials: JB
authors.lastname: Nielsen
mesh_terms: D003210:Concept Formation; D006801:Humans; D009125:Muscle Relaxants, Central / Q000627:therapeutic use; D009128:Muscle Spasticity / Q000175:diagnosis / Q000188:drug therapy / Q000534:rehabilitation; D009129:Muscle Tonus / Q000187:drug effects / Q000502:physiology; D026741:Physical Therapy Modalities; D012021:Reflex, Abnormal / Q000187:drug effects / Q000502:physiology
chemical_list: D009125:Muscle Relaxants, Central