title: Mastoidectomy cavity obliteration with bioactive glass: a pilot study.
abstract: OBJECTIVE
  To show that mastoid cavities with continuous infections and cleaning problems can be obliterated with bioactive glass (BG) and to present results of a pilot study for 16 operations on adults.
  
  
  METHODS
  Case series with planned data collection.
  
  
  METHODS
  Päijät-Häme Central Hospital, Finland-a single ear, nose, and throat (ENT) hospital department serving a population of 216,000.
  
  
  METHODS
  Fourteen patients had a large open radical cavity with recurrent infections. Two ears had discharge and pain after simple mastoidectomy. A re-mastoidectomy included support of the cavity skin and obliteration with BG. The mean follow-up time was 2.2 years.
  
  
  RESULTS
  All ears became dry. One reoperation was needed as the fascia support to the ear canal (EC) skin was too weak, and part of the BG leaked into the EC. The ear stayed dry, and the missing BG was replaced in a reoperation. A slightly short musculoperiosteal flap supported the EC skin in 1 ear. A minor amount of BG leaked into the EC. The ear stayed dry. The aim was an ample ear canal. One ear was overfilled and required meatoplasty. Simple mastoid cavities were isolated from the middle ear and become asymptomatic.
  
  
  CONCLUSIONS
  In this pilot study, BG works safely and with success as an obliteration material in problematic open radical cavities. Bioactive glass seems to tolerate chronic infection in the mastoid and prevent postoperative infections.
authors.affiliation: ENT Department, Päijät-Häme Central Hospital, Lahti, Finland. juha.silvola@phks.fi
authors.forename: Juha Tapio
authors.initials: JT
authors.lastname: Silvola
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D018424:Cholesteatoma, Middle Ear / Q000601:surgery*; D005260:Female; D005898:Glass; D006801:Humans; D008297:Male; D008416:Mastoid / Q000601:surgery*; D008875:Middle Aged; D010033:Otitis Media / Q000601:surgery*; D010865:Pilot Projects; D011446:Prospective Studies; D055815:Young Adult
chemical_list: C403922:bioactive glass S53P4