title: Reevaluation of the effect of phenylephrine on resolution of nephrosplenic entrapment by the rolling procedure in 87 horses.
abstract: OBJECTIVE
  To evaluate the outcome in horses treated with a rolling technique or surgically for nephrosplenic entrapment of the large colon (NSE) and to examine the benefit of phenylephrine (PE) HCl on the efficacy of nonsurgical (rolling) management of NSE.
  
  
  METHODS
  Case series.
  
  
  METHODS
  Horses (n = 211) diagnosed with NSE by rectal palpation with or without ultrasonography, or at the time of exploratory celiotomy or necropsy.
  
  
  METHODS
  Medical records (January 1, 2001-September 1, 2008) were collected from horses diagnosed with NSE at 2 referral centers. Records were used to obtain signalment, physical exam findings, laboratory results, ultrasonographic findings, the use of PE HCl, the specific treatment used, and outcome. Rectal findings indicative of NSE were: (1) palpation of large colon within the nephrosplenic space or (2) palpation of colonic bands coursing dorsally toward the nephrosplenic space in association with ultrasonographic findings suggestive of NSE.
  
  
  RESULTS
  Rolling was successful in 50 of 87 (58%) horses, 85 horses (98%) survived to discharge. Horses (n = 155) that were treated surgically (42 of which had previously undergone the rolling procedure) had a 94% short-term survival rate. Premedication with PE resulted in no significant difference (P = .91) in resolution of NSE by rolling.
  
  
  CONCLUSIONS
  Resolution of NSE by rolling was not significantly affected by premedication with PE in the population studied.
authors.affiliation: Peterson & Smith Equine Hospital and University of Florida Veterinary Medical Center, FL, USA. wtruebaker@gmail.com
authors.forename: William True
authors.initials: WT
authors.lastname: Baker
authors.forename: Jeremy
authors.initials: J
authors.lastname: Frederick
authors.forename: Steve
authors.initials: S
authors.lastname: Giguere
authors.forename: Timothy M
authors.initials: TM
authors.lastname: Lynch
authors.forename: Heather D
authors.initials: HD
authors.lastname: Lehmkuhl
authors.forename: Donnie E
authors.initials: DE
authors.lastname: Slone
mesh_terms: D000818:Animals; D003108:Colonic Diseases / Q000188:drug therapy / Q000601:surgery / Q000662:veterinary*; D013505:Digestive System Surgical Procedures / Q000662:veterinary*; D006734:Horse Diseases; D006736:Horses; D010656:Phenylephrine
chemical_list: D010656:Phenylephrine