title: Magnetic solid-phase extraction based on diphenyl functionalization of Fe3O4 magnetic nanoparticles for the determination of polycyclic aromatic hydrocarbons in urine samples.
abstract: Superparamagnetic Fe(3)O(4) diphenyl nanoparticles were prepared according to a solvothernal procedure and characterized by X-ray diffraction, infrared spectroscopy, surface area measurements, scanning electron microscopy, X-ray photoelectron spectroscopy and transmission electron microscopy. The magnetic phases present in the nanoparticle samples were analyzed by thermomagnetic analysis and the samples' magnetic properties were studied by vibrating sample magnetometry. The resulting nanoparticles having an average diameter of 200 nm were then used as solid-phase extraction sorbent for the determination of polycyclic aromatic hydrocarbons in urine samples. Method validation proved the feasibility of the developed beads for the quantitation of the investigated analytes at trace levels obtaining lower limit of quantitation values in the ng/l range. A good precision with coefficients of variations always lower than 15% was obtained. Finally, the superior extraction performance of the synthesized nanoparticles with respect to commercially available beads was proved.
authors.affiliation: Dipartimento di Chimica Generale ed Inorganica, Chimica Analitica, Chimica Fisica, Parco Area delle Scienze 17/A, 43124 Parma, Italy. federica.bianchi@unipr.it
authors.forename: F
authors.initials: F
authors.lastname: Bianchi
authors.forename: V
authors.initials: V
authors.lastname: Chiesi
authors.forename: F
authors.initials: F
authors.lastname: Casoli
authors.forename: P
authors.initials: P
authors.lastname: Luches
authors.forename: L
authors.initials: L
authors.lastname: Nasi
authors.forename: M
authors.initials: M
authors.lastname: Careri
authors.forename: A
authors.initials: A
authors.lastname: Mangia
mesh_terms: D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods; D006801:Humans; D057230:Limit of Detection; D058185:Magnetite Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D056951:Photoelectron Spectroscopy; D011084:Polycyclic Aromatic Hydrocarbons / Q000302:isolation & purification / Q000652:urine*; D052616:Solid Phase Extraction / Q000379:methods*; D014961:X-Ray Diffraction
chemical_list: D058185:Magnetite Nanoparticles; D011084:Polycyclic Aromatic Hydrocarbons