title: Escherichia coli O104:H4 infections and international travel.
abstract: We analyzed travel-associated clinical isolates of Escherichia coli O104:H4, including 1 from the 2011 German outbreak and 1 from a patient who returned from the Philippines in 2010, by genome sequencing and optical mapping. Despite extensive genomic similarity between these strains, key differences included the distribution of toxin and antimicrobial drug-resistance determinants.
authors.affiliation: Public Health Ontario, Toronto, Ontario, Canada
authors.forename: David C
authors.initials: DC
authors.lastname: Alexander
authors.forename: Weilong
authors.initials: W
authors.lastname: Hao
authors.forename: Matthew W
authors.initials: MW
authors.lastname: Gilmour
authors.forename: Sandra
authors.initials: S
authors.lastname: Zittermann
authors.forename: Alicia
authors.initials: A
authors.lastname: Sarabia
authors.forename: Roberto G
authors.initials: RG
authors.lastname: Melano
authors.forename: Analyn
authors.initials: A
authors.lastname: Peralta
authors.forename: Marina
authors.initials: M
authors.lastname: Lombos
authors.forename: Keisha
authors.initials: K
authors.lastname: Warren
authors.forename: Yuri
authors.initials: Y
authors.lastname: Amatnieks
authors.forename: Evangeline
authors.initials: E
authors.lastname: Virey
authors.forename: Jennifer H
authors.initials: JH
authors.lastname: Ma
authors.forename: Frances B
authors.initials: FB
authors.lastname: Jamieson
authors.forename: Donald E
authors.initials: DE
authors.lastname: Low
authors.forename: Vanessa G
authors.initials: VG
authors.lastname: Allen
mesh_terms: D000368:Aged; D001426:Bacterial Proteins / Q000235:genetics; D002170:Canada / Q000453:epidemiology; D004196:Disease Outbreaks; D004927:Escherichia coli Infections / Q000175:diagnosis / Q000453:epidemiology* / Q000382:microbiology; D016680:Genome, Bacterial; D006801:Humans; D007223:Infant; D008297:Male; D017422:Sequence Analysis, DNA; D054323:Shiga-Toxigenic Escherichia coli / Q000235:genetics / Q000302:isolation & purification*; D014195:Travel
chemical_list: D001426:Bacterial Proteins