title: Seizures and X-linked intellectual disability.
abstract: Intellectual disability occurs as an isolated X-linked trait and as a component of recognizable X-linked syndromes in the company of somatic, metabolic, neuromuscular, or behavioral abnormalities. Seizures accompany intellectual disability in almost half of these X-linked disorders. The spectrum of seizures found in the X-linked intellectual disability syndromes is broad, varying in time of onset, type of seizure, and response to anticonvulsant therapy. The majority of the genes associated with XLID and seizures have now been identified.
authors.affiliation: Greenwood Genetic Center, 106 Gregor Mendel Circle, Greenwood, SC 29646, USA. res@ggc.org
authors.forename: Roger E
authors.initials: RE
authors.lastname: Stevenson
authors.forename: Kenton R
authors.initials: KR
authors.lastname: Holden
authors.forename: R Curtis
authors.initials: RC
authors.lastname: Rogers
authors.forename: Charles E
authors.initials: CE
authors.lastname: Schwartz
mesh_terms: D000015:Abnormalities, Multiple / Q000235:genetics; D001921:Brain / Q000002:abnormalities; D004827:Epilepsy / Q000235:genetics* / Q000378:metabolism; D006801:Humans; D038901:X-Linked Intellectual Disability / Q000235:genetics*; D008661:Metabolism, Inborn Errors / Q000235:genetics; D010641:Phenotype; D013577:Syndrome