title: Influence of subinhibitory concentrations of cefotaxime, imipenem and ciprofloxacin on adhesion of Escherichia coli strains to polystyrene.
abstract: The present study investigated the ability of sub MICs of cefotaxime, imipenem and ciprofloxacin to interfere with adhesion of E. coli strains to polystyrene (selected polymer used in studies on microorganisms' adhesion). It was observed that cefotaxime and imipenem at 1/2 and 1/4 MICs decreased the adherence of E. coli strains to polystyrene significantly. 1/2, 1/4 and 1/8 MICs of ciprofloxacin generally decreased the adhesive properties of E. coli strains, but two E. coli strains showed a noticeable enhancement of adhesion after incubation at sub MICs of this antibiotic.
authors.affiliation: Department of Clinical Microbiology, Nicolaus Copernicus University in Toruń Ludwik Rydygier Collegium Medicum in Bydgoszcz, Poland. patrycjazalas@go2.pl
authors.forename: Patrycja
authors.initials: P
authors.lastname: Zalas-Wiecek
authors.forename: Eugenia
authors.initials: E
authors.lastname: Gospodarek
authors.forename: Katarzyna
authors.initials: K
authors.lastname: Piecyk
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001422:Bacterial Adhesion / Q000187:drug effects*; D002439:Cefotaxime / Q000494:pharmacology; D002939:Ciprofloxacin / Q000494:pharmacology; D004926:Escherichia coli / Q000187:drug effects*; D006801:Humans; D015378:Imipenem / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D011137:Polystyrenes
chemical_list: D000900:Anti-Bacterial Agents; D011137:Polystyrenes; D002939:Ciprofloxacin; D015378:Imipenem; D002439:Cefotaxime