title: Systematic review and case series of neuropsychological functioning after epilepsy surgery in children with dysembryoplastic neuroepithelial tumors (DNET).
abstract: BACKGROUND
  The purposes of this study were to 1) conduct a review of neuropsychological (NP) outcomes after epilepsy surgery for DNET and 2) present pre/post-surgical NP results from a series of children with DNET.
  
  
  METHODS
  First, a systematic literature review was conducted with specific inclusion criteria. Second, a review of DNET surgical patients seen at two tertiary-care hospitals using reliable change methods of NP functioning was conducted.
  
  
  RESULTS
  Of 300 citations retrieved, 7 studies met criteria. Studies reported low average to average pre-surgical IQ. Engel Class I outcome was approximately 85%.
  
  
  METHODS
  Thirteen children completed pre/post-surgical NP assessments. Pre-surgically, children demonstrated low average to average functioning. Post-surgically, few patients showed reliable change. One-third of children demonstrated psychological improvement.
  
  
  CONCLUSIONS
  NP outcome following DNET has not been well-described. Children with DNET demonstrate low average to average NP functioning pre-surgically, good seizure outcome, and stable NP functioning post-surgically.
authors.affiliation: Alberta Health Services, Canada. Taryn.Fay-McClymont@albertahealthservices.ca
authors.forename: Taryn B
authors.initials: TB
authors.lastname: Fay-McClymont
authors.forename: Marianne
authors.initials: M
authors.lastname: Hrabok
authors.forename: Elisabeth M S
authors.initials: EM
authors.lastname: Sherman
authors.forename: Walter J
authors.initials: WJ
authors.lastname: Hader
authors.forename: Mary B
authors.initials: MB
authors.lastname: Connolly
authors.forename: Sare
authors.initials: S
authors.lastname: Akdag
authors.forename: Ismail S
authors.initials: IS
authors.lastname: Mohamed
authors.forename: Samuel
authors.initials: S
authors.lastname: Wiebe
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003072:Cognition Disorders / Q000209:etiology / Q000601:surgery*; D004827:Epilepsy / Q000150:complications / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D018302:Neoplasms, Neuroepithelial / Q000150:complications / Q000601:surgery*; D009483:Neuropsychological Tests; D010372:Pediatrics; D012189:Retrospective Studies; D013724:Teratoma / Q000150:complications / Q000601:surgery*; D016896:Treatment Outcome