title: Alopecia areata in two black Angus cows.
abstract: Adult onset progressive alopecia and leukotrichia developed in 2 registered black Angus cows, aged 6 and 7 years. Histopathologic findings in skin were prominent melanin clumping and degeneration of matrix cells with formation of giant multinucleate cells within hair bulbs, accompanied by peribulbar melanin incontinence and fibrosis and dystrophic hair shafts. Intrabulbar and peribulbar lymphocytes were cluster of differentiation (CD)3-positive T cells. Findings were characteristic of alopecia areata.
authors.affiliation: College of Veterinary Medicine, Oregon State University, Corvallis, OR 97331, USA. Beth.Valentine@oregonstate.edu
authors.forename: Beth A
authors.initials: BA
authors.lastname: Valentine
authors.forename: Robert J
authors.initials: RJ
authors.lastname: Bildfell
authors.forename: David
authors.initials: D
authors.lastname: Packham
authors.forename: Danny W
authors.initials: DW
authors.lastname: Scott
authors.forename: William H
authors.initials: WH
authors.lastname: Miller
mesh_terms: D000506:Alopecia Areata / Q000473:pathology / Q000662:veterinary*; D000818:Animals; D001706:Biopsy / Q000662:veterinary; D002417:Cattle; D002418:Cattle Diseases / Q000473:pathology*; D005260:Female; D007150:Immunohistochemistry / Q000662:veterinary