title: Marine carotenoids and oxidative stress.
abstract: Oxidative stress induced by reactive oxygen species plays an important role in the etiology of many diseases. Dietary phytochemical products, such as bioactive food components and marine carotenoids (asthaxantin, lutein, β-carotene, fucoxanthin), have shown an antioxidant effect in reducing oxidative markers stress. Scientific evidence supports the beneficial role of phytochemicals in the prevention of some chronic diseases. Many carotenoids with high antioxidant properties have shown a reduction in disease risk both in epidemiological studies and supplementation human trials. However, controlled clinical trials and dietary intervention studies using well-defined subjects population have not provided clear evidence of these substances in the prevention of diseases. The most important aspects of this special issue will cover the synthesis, biological activities, and clinical applications of marine carotenoids, with particular attention to recent evidence regarding anti-oxidant and anti-inflammatory properties in the prevention of cardiovascular disease.
authors.affiliation: Cardiology Unit, San Camillo de Lellis Hospital, via Isonzo, Manfredonia, Foggia 71043, Italy.|Human Nutrition, Department of Biomedical Science, via Dei vestini, University G, D'Annunzio, Chieti 66013, Italy.
authors.forename: Graziano
authors.initials: G
authors.lastname: Riccioni
mesh_terms: D000818:Animals; D002318:Cardiovascular Diseases / Q000517:prevention & control; D002338:Carotenoids / Q000494:pharmacology*; D006801:Humans; D014975:Lutein / Q000494:pharmacology; D018384:Oxidative Stress / Q000187:drug effects*; D024341:Xanthophylls / Q000494:pharmacology; D019207:beta Carotene / Q000494:pharmacology
chemical_list: D024341:Xanthophylls; D019207:beta Carotene; C025164:fucoxanthin; D002338:Carotenoids; D014975:Lutein