title: Ultrasensitive electrochemical detection of prostate-specific antigen (PSA) using gold-coated magnetic nanoparticles as 'dispersible electrodes'.
abstract: Herein, we demonstrate the use of modified gold-coated magnetic nanoparticles as 'dispersible electrodes' which act as selective capture vehicles for electrochemical detection of prostate-specific antigen (PSA). A key advantage of this system is the ability to quantify non-electrochemical active analytes such as proteins with unprecedented detection limits and fast response times.
authors.affiliation: School of Chemistry and The Australian Centre for Nanomedicine, University of New South Wales, Sydney, NSW 2052, Australia.
authors.forename: Kyloon
authors.initials: K
authors.lastname: Chuah
authors.forename: Leo M H
authors.initials: LM
authors.lastname: Lai
authors.forename: Ian Y
authors.initials: IY
authors.lastname: Goon
authors.forename: Stephen G
authors.initials: SG
authors.lastname: Parker
authors.forename: Rose
authors.initials: R
authors.lastname: Amal
authors.forename: J
authors.initials: J
authors.lastname: Justin Gooding
mesh_terms: D000911:Antibodies, Monoclonal / Q000276:immunology; D015374:Biosensing Techniques; D004563:Electrochemistry; D052203:Ferrosoferric Oxide / Q000737:chemistry*; D006046:Gold / Q000737:chemistry*; D008855:Microscopy, Electron, Scanning; D046529:Microscopy, Electron, Transmission; D053758:Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D017430:Prostate-Specific Antigen / Q000032:analysis* / Q000276:immunology
chemical_list: D000911:Antibodies, Monoclonal; D006046:Gold; D017430:Prostate-Specific Antigen; D052203:Ferrosoferric Oxide