title: [The age factor in bilateral hydrocele diagnosis secondary to a primitive testis lymphoma: case report, diagnosis and therapy].
abstract: Primitive NHL represents 9% of testis tumours and the 85% is diagnosed in patient older thant 60 years old. Usually pain and a testis mass are the main manifestations. The Authors report the case of a 82 years-old man with bilateral hydrocele causing severe alteration in the deambulation. The cytology did not show blood cells or neoplastic cell in the FNAB. The US showed a complete modification in the testis. The patient underwent to surgery intervention of vaginalis tunic eversion and resection with the aim of control the symptoms. The histology on multiple biopsy of testis and epidydims bilaterally showed a large B-cell lymphoma. The patient was treated with 6 chemotheray cycles (Rituximab, Vincristine, Cyclophosphamide, Prednisone). Bilateral hydrocele is a rare clinical presentation of testis NHL. In this patient, blood and neoplastic cell absence in the cytology made difficult the differential diagnosis between inflammatory pathology and neoplasia. Hystopathologic study and immunologic pattern can make a certain diagnosis.
authors.affiliation: Dipartimento di Scienze Medico-Chirurgiche e Biotecnologie, Sapienza Università di Roma, Polo Pontino, Ospedale A. Fiorini, Terracina, Latina, Italia.
authors.forename: E
authors.initials: E
authors.lastname: Spaziani
authors.forename: A
authors.initials: A
authors.lastname: Di Filippo
authors.forename: M
authors.initials: M
authors.lastname: Picchio
authors.forename: F
authors.initials: F
authors.lastname: De Angelis
authors.forename: S
authors.initials: S
authors.lastname: Corazza
authors.forename: F
authors.initials: F
authors.lastname: Narilli
authors.forename: G
authors.initials: G
authors.lastname: Cimino
mesh_terms: D017668:Age of Onset; D000369:Aged, 80 and over; D058846:Antibodies, Monoclonal, Murine-Derived / Q000008:administration & dosage; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000627:therapeutic use; D044963:Biopsy, Fine-Needle; D003131:Combined Modality Therapy; D003520:Cyclophosphamide / Q000008:administration & dosage; D003937:Diagnosis, Differential; D004317:Doxorubicin / Q000008:administration & dosage; D006801:Humans; D016403:Lymphoma, Large B-Cell, Diffuse / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology / Q000601:surgery; D008297:Male; D009920:Orchitis / Q000175:diagnosis; D011241:Prednisone / Q000008:administration & dosage; D000069283:Rituximab; D006848:Testicular Hydrocele / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D013736:Testicular Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology / Q000601:surgery; D014463:Ultrasonography; D014750:Vincristine / Q000008:administration & dosage
chemical_list: D058846:Antibodies, Monoclonal, Murine-Derived; D000069283:Rituximab; D014750:Vincristine; D004317:Doxorubicin; D003520:Cyclophosphamide; D011241:Prednisone