title: Efficient dynamic kinetic resolution of racemic secondary alcohols by a chemoenzymatic system using bifunctional iridium complexes with C-N chelate amido ligands.
abstract: The combined catalyst system of bifunctional amidoiridium complexes derived from benzylic amines with CALB was found to provide a range of chiral acetates from racemic secondary alcohols in excellent yields with nearly perfect enantioselectivities via dynamic kinetic resolution.
authors.affiliation: Department of Applied Chemistry, Graduate School of Science and Engineering, Tokyo Institute of Technology, O-okayama 2-12-1-E4-1, Tokyo 152-8552, Japan.
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Sato
authors.forename: Yoshihito
authors.initials: Y
authors.lastname: Kayaki
authors.forename: Takao
authors.initials: T
authors.lastname: Ikariya
mesh_terms: D000438:Alcohols / Q000737:chemistry*; D002384:Catalysis; D007495:Iridium / Q000737:chemistry*; D007700:Kinetics; D008024:Ligands; D013237:Stereoisomerism
chemical_list: D000438:Alcohols; D008024:Ligands; D007495:Iridium