title: Oral triptans in the preventive management of cluster headache.
abstract: Cluster headache is a rare primary neurovascular headache and a severe pain condition with unilateral headache over 15-180 minutes and concomitant unilateral autonomic symptoms. The detailed pathophysiology of the condition is still unclear. Only a few evidence-based therapeutic options for acute therapy and the preventive management of the disease are available. Triptans, in particular sumatriptan 6 mg subcutaneously, are highly effective for acute treatment. This review focuses on the potential use of oral triptans in the prophylaxis of cluster headache.
authors.affiliation: Department of Neurology, Cologne City Hospitals, University of Cologne, Cologne, Germany. pagelerl@kliniken-koeln.de
authors.forename: Lutz
authors.initials: L
authors.lastname: Pageler
authors.forename: Volker
authors.initials: V
authors.lastname: Limmroth
mesh_terms: D000284:Administration, Oral; D003027:Cluster Headache / Q000188:drug therapy* / Q000503:physiopathology / Q000517:prevention & control*; D005260:Female; D006801:Humans; D008297:Male; D010102:Oxygen Inhalation Therapy; D017410:Practice Guidelines as Topic; D016032:Randomized Controlled Trials as Topic; D018170:Sumatriptan / Q000008:administration & dosage; D016896:Treatment Outcome; D014363:Tryptamines / Q000008:administration & dosage*
chemical_list: D014363:Tryptamines; D018170:Sumatriptan