title: [Metabolic disorders as a result of intestine ischemia and it's defensive factors due to aorta prosthetics and cross-clamping of descending aorta before celiac trunk].
abstract: The perfusion of internal organs is affected during cardiac surgery of descending aorta and cross-clamping before (upper) celiac trunk as well as extracorporeal circulation. The aim of study is to investigated methods of decreasing negative effects on intestine perfusion which leads to metabolic disorder. Two groups were studied: 11 patient with epidural anesthesia and 11 patient with pulmonary atrium-femoral bypass. For mesenterial perfusion monitoring was used intraluminal tonometry. 11 patient of control group had significant changes in level of lactate and glucose as well as data of intraluminal tonometry which is evidence of mesenterial ischemia. Same changes were discovered in the group of patient with epidural anesthesia. However group with pulmonary atrium - femoral bypass had minimal metabolic abnormalities similarly to data of tonometry. Above all administrating epidural anesthesia had positive effect in early post operative period and restore intestine motility.
mesh_terms: D000767:Anesthesia, Epidural / Q000379:methods*; D001013:Aorta, Thoracic / Q000601:surgery; D006348:Cardiac Surgical Procedures / Q000009:adverse effects / Q000379:methods; D005112:Extracorporeal Circulation; D005260:Female; D005769:Gastrointestinal Motility; D005947:Glucose / Q000378:metabolism; D006801:Humans; D007422:Intestines / Q000098:blood supply*; D007511:Ischemia / Q000150:complications* / Q000209:etiology; D019344:Lactic Acid / Q000378:metabolism; D008297:Male; D008365:Manometry / Q000379:methods; D008659:Metabolic Diseases / Q000209:etiology*; D011184:Postoperative Period
chemical_list: D019344:Lactic Acid; D005947:Glucose