title: Reactive arthritis after the intravesical instillation of BCG.
abstract: The intravesical instilation of bacillus Calmette-Guérin (BCG) is a widely used and efficacious procedure for treatment of intermediate to high-grade superficial bladder cancer. The occurrence of osteoarticular side effects is infrequent compared to the number of administrated doses, and reactive arthritis is included within these effects. We present the case of a 54 years old HLA-27 (+) male, who developed reactive arthritis featuring asymmetric olygoarthritis and dactylitis after the second intravesical BCG instillation, which was resolved with administration of Etoricoxib and Isoniazid.
authors.affiliation: Servicio de Reumatología, Hospital Universitario Ramón y Cajal, Madrid, Spain. ccmacia@gmail.com
authors.forename: Cristina
authors.initials: C
authors.lastname: Macía Villa
authors.forename: Walter
authors.initials: W
authors.lastname: Sifuentes Giraldo
authors.forename: Alina
authors.initials: A
authors.lastname: Boteanu
authors.forename: Mariano
authors.initials: M
authors.lastname: González Lanza
authors.forename: Javier
authors.initials: J
authors.lastname: Bachiller Corral
mesh_terms: D000283:Administration, Intravesical; D016918:Arthritis, Reactive / Q000209:etiology*; D001500:BCG Vaccine / Q000009:adverse effects* / Q000627:therapeutic use; D002295:Carcinoma, Transitional Cell / Q000150:complications / Q000601:surgery / Q000628:therapy; D003131:Combined Modality Therapy; D020022:Genetic Predisposition to Disease; D015796:HLA-B27 Antigen / Q000032:analysis; D015793:HLA-B7 Antigen / Q000032:analysis; D006801:Humans; D007167:Immunotherapy; D007322:Instillation, Drug; D008297:Male; D008875:Middle Aged; D001749:Urinary Bladder Neoplasms / Q000150:complications / Q000601:surgery / Q000628:therapy
chemical_list: D001500:BCG Vaccine; D015796:HLA-B27 Antigen; D015793:HLA-B7 Antigen