title: Osteogenesis imperfecta and bone marrow transplant.
abstract: The first attempted bone marrow transplant (BMT) dates back to 1896. In the following centuries, the medical community pioneered an ongoing progression of breakthroughs. In 1954 the first successful solid organ transplant, the kidney, was performed. In the 1960s advances led to the first successful lung, pancreas, liver and heart transplant and in 1973 the first successful BMT was achieved. BMT has traditionally been used to treat malignant diseases. However, scientific and technological progress has expanded its scope and today, BMT is used to treat a spectrum of diseases. While BMT is a complex procedure, the medical community expects that it will one day play a role in the treatment of other diseases. As the science evolves, it is essential that nurses educate themselves about these emerging transplant populations, one of which is children with osteogenesis impefecta. This manuscript will provide nurses with a critical background on the disease, a description of the transplant theory, and the implications for the nursing care of these children.
authors.affiliation: University of Pennsylvania, Philadelphia, USA. lara.madonia@gmail.com
authors.forename: Lara
authors.initials: L
authors.lastname: Madonia
mesh_terms: D016026:Bone Marrow Transplantation / Q000451:nursing; D002648:Child; D006801:Humans; D010013:Osteogenesis Imperfecta / Q000175:diagnosis / Q000601:surgery*; D010371:Pediatric Nursing; D011379:Prognosis