title: [Mould and mycotoxin contamination of medicinal materials].
abstract: Medicinal materials may be contaminated with a broad variety of fungi, which are represented by Aspergillus spp, Penlicillium spp, Fusarium spp, Rhizopus spp, Mucor spp et al. This fact limits the utilization of medicinal materials, besides, medicinal materials may also be contaminated with mycotoxins produced by these fungi, and bring harm to human health. Several mycotoxins have been detected in medicinal materials, such as AFTs, OTA, FBs, et al. The contamination may originate from the conditions in which the medicinal plants are cultivated, stored and in the finished product manufacturing stages. Some methods have been used for detoxifcation and disinfection for medicinal materials, but they have limited effects. Taking into consideration the background situation, it is important for medicinal materials to be protected from contamination of fungi at every stage of production. The present study intends to give a review of contamination of medicinal materials by moulds and mycotoxins and discuss the factors influencing this situation, expecting to contribute to the knowledge for reducing the contamination.
authors.affiliation: Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Institute of Medicinal Plant Development, Peking Union Medical College, Beijing 100193, China.
authors.forename: Xiaomao
authors.initials: X
authors.lastname: Qin
authors.forename: Shunxing
authors.initials: S
authors.lastname: Guo
mesh_terms: D004340:Drug Contamination / Q000517:prevention & control; D005658:Fungi / Q000302:isolation & purification*; D009183:Mycotoxins / Q000032:analysis*
chemical_list: D009183:Mycotoxins