title: [Slow onset septic arthritis by Scedosporium apiospermum after periarticular infiltration].
abstract: BACKGROUND
  Fungal arthritis is usually of haematogenous origin, and mainly affects patients with impaired cellular immunity or users of intravenous drugs. The infection in immunocompetent patients is generally caused by direct inoculation of the microorganism through an invasive device. The experience of azole therapy in these patients is limited.
  
  
  METHODS
  We report a case of arthritis caused by Scedosporium apiospermum characterized by its slow onset, lack of response to posaconazole and caspofungin, and its successful resolution after surgical debridement and treatment with voriconazole.
  
  
  CONCLUSIONS
  Treatment with voriconazole and surgical debridement is an effective therapy for arthritis due to S. apiospermum.
authors.affiliation: Unidad de Enfermedades Infecciosas, Servicio de Medicina Interna, Hospital Universitario Puerta de Hierro, Universidad Autónoma de Madrid, Majadahonda, Madrid, España. aramos220@gmail.com
authors.forename: Antonio
authors.initials: A
authors.lastname: Ramos Martínez
authors.forename: Beatriz
authors.initials: B
authors.lastname: Orden Martínez
authors.forename: Jessica
authors.initials: J
authors.lastname: Polo Laborda
authors.forename: Blanca
authors.initials: B
authors.lastname: García Magallón
authors.forename: Mónica
authors.initials: M
authors.lastname: Fernández Castro
authors.forename: Carlos
authors.initials: C
authors.lastname: Ortega Sánchez
authors.forename: Manuel
authors.initials: M
authors.lastname: Gil Navarro
mesh_terms: D000369:Aged, 80 and over; D001170:Arthritis, Infectious / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D004551:Elbow Joint; D006801:Humans; D007279:Injections, Subcutaneous; D008297:Male; D009181:Mycoses / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D021681:Scedosporium; D013997:Time Factors