title: Health-related quality of life of liver transplant recipients: a single center experience.
abstract: OBJECTIVE
  To evaluate the health related quality of life (HRQOL) of liver transplant recipients and to identify risk factors influencing post-operative HRQOL.
  
  
  METHODS
  Adult patients who underwent primary liver transplantation from 2009 to 2010 were asked to complete a HRQOL survey at pre-operation and one year postoperatively. We compared the HRQOL of liver transplant recipients at pre-transplantation and one year postoperatively to the general population. Pre-transplant variables were analyzed to identify the risk factors influencing postoperative HRQOL.
  
  
  RESULTS
  Pre-transplant HRQOL was significantly lower than that of the general population and significantly improved at one year postoperatively. Multivariate analyses suggested hepatocellular carcinoma, pre-transplant hypertension and high model for end-stage liver disease score were independent risk factors for postoperative physical component summary (PCS); and higher education level, marital status and lower income level negatively impacted on the postoperative mental component summary (MCS).
  
  
  CONCLUSIONS
  Factors influencing postoperative HRQOL were identified in the present study. Transplant centers should pay more attention to patients with above-mentioned risk factors and strive to improve the HRQOL.
authors.affiliation: Division of Liver and Vascular Surgery, West China Hospital of Sichuan University, Chengdu, China. luoy16@126.com
authors.forename: Yan-Li
authors.initials: YL
authors.lastname: Luo
authors.forename: Xiao-Ling
authors.initials: XL
authors.lastname: Yang
authors.forename: Jin-Bo
authors.initials: JB
authors.lastname: Cui
authors.forename: Feng-Ming
authors.initials: FM
authors.lastname: Xiao
authors.forename: Yan
authors.initials: Y
authors.lastname: Liao
authors.forename: Tao
authors.initials: T
authors.lastname: Wu
authors.forename: Ai-Hua
authors.initials: AH
authors.lastname: Dong
authors.forename: Juan
authors.initials: J
authors.lastname: Wan
authors.forename: Zhe-Rong
authors.initials: ZR
authors.lastname: Xie
mesh_terms: D000328:Adult; D006528:Carcinoma, Hepatocellular / Q000523:psychology / Q000601:surgery; D016009:Chi-Square Distribution; D002681:China; D004522:Educational Status; D005260:Female; D006801:Humans; D006973:Hypertension / Q000523:psychology; D007182:Income; D008107:Liver Diseases / Q000175:diagnosis / Q000503:physiopathology / Q000523:psychology / Q000601:surgery*; D008113:Liver Neoplasms / Q000523:psychology / Q000601:surgery; D016031:Liver Transplantation / Q000009:adverse effects / Q000523:psychology; D008297:Male; D017533:Marital Status; D008875:Middle Aged; D015999:Multivariate Analysis; D011788:Quality of Life; D018570:Risk Assessment; D012307:Risk Factors; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires; D013997:Time Factors; D016896:Treatment Outcome