title: Periprosthetic joint infection: are patients with multiple prosthetic joints at risk?
abstract: Patients who present with a periprosthetic joint infection in a single joint may have multiple prosthetic joints. The risk of these patients developing a subsequent infection in another prosthetic joint is unknown. Our purposes were (1) to identify the risk of developing a subsequent infection in another prosthetic joint and (2) to describe the time span and organism profile to the second prosthetic infection. We retrospectively identified 55 patients with periprosthetic joint infection who had another prosthetic joint in place at the time of presentation. Of the 55 patients, 11 (20%) developed a periprosthetic joint infection in a second joint. The type of organism was the same as the first infection in 4 (36%) of 11 patients. The time to developing a second infection averaged 2.0 years (range, 0-6.9 years).
authors.affiliation: Rothman Institute Orthopaedics, Thomas Jefferson University Hospital, 925 Chestnut Street, Philadelphia, PA 19107, USA.
authors.forename: S Mehdi
authors.initials: SM
authors.lastname: Jafari
authors.forename: David S
authors.initials: DS
authors.lastname: Casper
authors.forename: Camilo
authors.initials: C
authors.lastname: Restrepo
authors.forename: Benjamin
authors.initials: B
authors.lastname: Zmistowski
authors.forename: Javad
authors.initials: J
authors.lastname: Parvizi
authors.forename: Peter F
authors.initials: PF
authors.lastname: Sharkey
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006622:Hip Prosthesis / Q000382:microbiology*; D006801:Humans; D015994:Incidence; D007720:Knee Prosthesis / Q000382:microbiology*; D008297:Male; D008875:Middle Aged; D016459:Prosthesis-Related Infections / Q000175:diagnosis / Q000453:epidemiology* / Q000382:microbiology; D012189:Retrospective Studies; D012307:Risk Factors; D013997:Time Factors