title: The synthesis and characterization N-methyl-3-phenyl-norbornan-2-amine (Camfetamine™).
abstract: N-Methyl-3-phenyl-norbornan-2-amine (N-methyl-3-phenylbicyclo[2.2.1]heptan-2-amine, Camfetamine(™) ) is available from a number of online legal highs/research chemicals' vendors. Although it was developed as an analeptic by Merck in the early 1960s, it was never commercialized. However, the Association of Independent Research Chemical Retailers (AIRCR), an umbrella organization for a number of online vendors, has redeveloped it for use as a recreational drug. N-Methyl-3-phenyl-norbornan-2-amine is closely related to fencamfamine which has been widely used as a central nervous system (CNS) stimulant and appetite suppressant. In this paper we describe the synthesis of N-methyl-3-phenyl-norbornan-2-amine, its characterization and interpretations of its electron impact, and electrospray ionization mass spectra.
authors.affiliation: Department of Pharmacology and Therapeutics, School of Medicine, Trinity Centre for Health Sciences, St James's Hospital, Dublin, Ireland. pierce.kavanagh@tcd.ie
authors.forename: Pierce
authors.initials: P
authors.lastname: Kavanagh
authors.forename: Daniel
authors.initials: D
authors.lastname: Angelov
authors.forename: John
authors.initials: J
authors.lastname: O'Brien
authors.forename: John D
authors.initials: JD
authors.lastname: Power
authors.forename: Seán D
authors.initials: SD
authors.lastname: McDermott
authors.forename: Brian
authors.initials: B
authors.lastname: Talbot
authors.forename: John
authors.initials: J
authors.lastname: Fox
authors.forename: Cora
authors.initials: C
authors.lastname: O'Donnell
authors.forename: Rachel
authors.initials: R
authors.lastname: Christie
mesh_terms: D001067:Appetite Depressants / Q000138:chemical synthesis* / Q000737:chemistry; D000697:Central Nervous System Stimulants / Q000138:chemical synthesis* / Q000737:chemistry; D013287:Illicit Drugs / Q000138:chemical synthesis* / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D009636:Norbornanes / Q000138:chemical synthesis* / Q000737:chemistry; D021241:Spectrometry, Mass, Electrospray Ionization
chemical_list: D001067:Appetite Depressants; D000697:Central Nervous System Stimulants; D013287:Illicit Drugs; D009636:Norbornanes