title: Isolated tubercular splenic abscess: can we defer splenectomy? Our single experience with anti-tuberculous therapy alone.
abstract: Isolated splenic tuberculosis is an exceedingly rare clinical condition. Microbiological confirmation of diagnosis in such cases is quite difficult. We encountered the case of a 35-year-old female, who presented with persistent low-grade fever and weight loss. The CT scan of the abdomen revealed multiple hypodense splenic lesions. No primary focus of infection was detected in any other organs. Fine needle aspiration of splenic lesion revealed acid-fast bacilli on Ziehl-Neelsen stain. With anti-tuberculous therapy, the lesions regressed significantly in size. We stress that splenic tuberculosis should be considered as a diagnostic possibility even in immunocompetent individuals and choose combination antituberculous therapy as the first line treatment with consideration of splenectomy depending on response.
authors.affiliation: Department of Medicine, Medical College and Hospital, Kolkata - 700073, India. sayantan.ray@gmail.com
authors.forename: S
authors.initials: S
authors.lastname: Ray
authors.forename: S
authors.initials: S
authors.lastname: Kundu
authors.forename: M
authors.initials: M
authors.lastname: Goswami
authors.forename: D
authors.initials: D
authors.lastname: Sarkar
authors.forename: M
authors.initials: M
authors.lastname: Saha
mesh_terms: D000038:Abscess / Q000175:diagnosis* / Q000188:drug therapy* / Q000473:pathology; D000328:Adult; D000995:Antitubercular Agents / Q000008:administration & dosage*; D044963:Biopsy, Fine-Needle; D005260:Female; D005334:Fever / Q000175:diagnosis / Q000209:etiology; D006801:Humans; D008853:Microscopy; D011860:Radiography, Abdominal; D013156:Splenectomy; D013158:Splenic Diseases / Q000175:diagnosis* / Q000188:drug therapy* / Q000473:pathology; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D014376:Tuberculosis / Q000175:diagnosis* / Q000188:drug therapy* / Q000473:pathology; D015431:Weight Loss
chemical_list: D000995:Antitubercular Agents