title: Anaphylactic shock and hyperfibrinolysis measured with thromboelastography.
abstract: This case report presents anaphylactic shock in which hyperfibrinolysis was diagnosed with Thromboelastography (TEG). A 45 year old female patient was scheduled for vacuum-assisted wound closure. At induction, she developed an anaphylactic shock that stabilized after standard treatment. TEG analysis revealed hyperfibrinolysis. Surgery was delayed and there were no signs of spontaneous bleeding. A repeat TEG analysis performed 30 minutes later showed a completely normalized coagulation pattern. Few reports have documented the association between anaphylactic shock and hyperfibrinolysis. This case illustrates the transient and short-lived nature of the phenomenon. The mechanisms and potential consequences are discussed.
authors.affiliation: Dept of Anesthesiology, University Hospital Ghent, De Pintelaan 185, 9000 Ghent, Belgium.
authors.forename: A
authors.initials: A
authors.lastname: Parashchanka
authors.forename: P A H
authors.initials: PA
authors.lastname: Wyffels
authors.forename: J G M
authors.initials: JG
authors.lastname: Van Limmen
authors.forename: P F
authors.initials: PF
authors.lastname: Wouters
mesh_terms: D000707:Anaphylaxis / Q000150:complications* / Q000209:etiology; D000758:Anesthesia / Q000009:adverse effects* / Q000379:methods; D001778:Blood Coagulation Disorders / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology; D005260:Female; D005342:Fibrinolysis; D006801:Humans; D008875:Middle Aged; D013916:Thrombelastography / Q000379:methods*