title: [New microsurgical model for the study of the morphological adaptative response of venous grafts].
abstract: BACKGROUND
  Animal models have been developed for the study of the intimal hyperplasia, a common cause of venous graft stenosis.
  
  
  OBJECTIVE
  To establish a venous graft animal model for the study of the morphologic adaptative response to the arterial circulation.
  
  
  METHODS
  A venous graft was placed in the arterial circulation of the caudal extremity from Wistar rats. In order to develop the model, it was carried out a morphologic study of the caudal extremity blood vessels. Three possible sites were evaluated for the obtaining of the venous graft.
  
  
  RESULTS
  Graft permeability and viability were observed only in one segment, between the muscular branches and the origin of the saphenous vein. The portion of vein that was obtained from one extremity, was placed in the arterial circulation of the opposite extremity.
  
  
  CONCLUSIONS
  A venous graft animal model was established, using a femoral vein segment, between the muscular branches and the origin of the saphenous vein, placing it in the homonyme artery of the opposite extremity.
authors.affiliation: Departamento de Anatomia Humana, Facultad de Medicina, Universidad Autónoma de Nuevo León, Monterrey, NL.
authors.forename: Alejandro
authors.initials: A
authors.lastname: Quiroga-Garza
authors.forename: Miriam
authors.initials: M
authors.lastname: Delgado-Brito
authors.forename: Juan José
authors.initials: JJ
authors.lastname: Bazaldúa-Cruz
authors.forename: Eliud
authors.initials: E
authors.lastname: Villarreal-Silva
authors.forename: Sergio E
authors.initials: SE
authors.lastname: Velázquez-Gauna
authors.forename: Rodrigo E
authors.initials: RE
authors.lastname: Elizondo-Omaña
authors.forename: Santos
authors.initials: S
authors.lastname: Guzmán-López
mesh_terms: D000818:Animals; D019917:Blood Vessel Prosthesis Implantation / Q000379:methods*; D005263:Femoral Artery / Q000473:pathology / Q000601:surgery; D005268:Femoral Vein / Q000637:transplantation; D006083:Graft Occlusion, Vascular / Q000209:etiology; D006614:Hindlimb / Q000098:blood supply; D006965:Hyperplasia; D008866:Microsurgery / Q000379:methods*; D023421:Models, Animal; D051381:Rats; D017208:Rats, Wistar; D012501:Saphenous Vein / Q000601:surgery; D017539:Tunica Intima / Q000473:pathology; D014654:Vascular Patency; D014680:Veins / Q000601:surgery*