title: Peri-implantitis: from diagnosis to therapeutics.
abstract: Peri-implantitis is an infection of the tissue around an implant, resulting in the loss of supporting bone. Risk factors for peri-implantitis consist of a history of periodontitis, dental plaque, poor oral hygiene, smoking, alcohol consumption and diabetes. A clinical diagnosis indicates inflammatory signs including bleeding on probing with or without suppuration and a peri-implant pocket depth ≥5 mm. A radiograph shows images of marginal bone loss ≥2 mm. A differential diagnosis of peri-implant mucositis, occlusal overload, retrograde peri-implantitis and inflammatory implant periapical lesions suggests the appropriate treatment in each case. The non-surgical treatment of peri-implantitis, including a mechanical treatment alone or combined with antiseptics or antibiotics can improve clinical parameters in the short term but residual defects may still persist. Surgical treatment such as guided bone regeneration results in a gain of clinical attachment level and bone reconstruction in the long term. The limited effect of laser-assisted therapy needs to be further evaluated. The concept of prevention based on early detection and regular maintenance plays a principal role in reducing the occurrence of peri-implantitis.
authors.affiliation: Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes, UMR CNRS 6236, IRD 198, Méditerranée Infection, Aix-Marseille University, Marseille, France.
authors.forename: Tung
authors.initials: T
authors.lastname: Nguyen-Hieu
authors.forename: Alain
authors.initials: A
authors.lastname: Borghetti
authors.forename: Gérard
authors.initials: G
authors.lastname: Aboudharam
mesh_terms: D016301:Alveolar Bone Loss / Q000209:etiology* / Q000628:therapy; D015921:Dental Implants / Q000009:adverse effects*; D006801:Humans; D057873:Peri-Implantitis / Q000175:diagnosis / Q000209:etiology* / Q000382:microbiology / Q000628:therapy; D012307:Risk Factors
chemical_list: D015921:Dental Implants