title: Chitooligosaccharides as potential nutraceuticals: production and bioactivities.
abstract: Chitooligosaccharide (COS), a derivative of chitosan, can be produced by either chemical or enzymatic hydrolysis. Looking back through past research, several technological approaches have been taken to prepare COSs, and enzymatic approaches are favorable due to their environmentally friendly methods, safety, and a lack of toxicity. Similar to chitosan, COSs can also be considered potential nutraceuticals due to their versatile biological activities, water-soluble properties, and absorption properties in the intestine. Therefore, this chapter provides certain methods for the preparation of COSs and addresses their biological properties such as antihypertensive, antioxidant, antitumor, antimicrobial, and other select biological activities.
authors.affiliation: School of Food Technology and Nutrition, Chonnam National University, Yeosu, Republic of Korea. jjy1915@jnu.ac.kr
authors.forename: Jae-Young
authors.initials: JY
authors.lastname: Je
authors.forename: Se-Kwon
authors.initials: SK
authors.lastname: Kim
mesh_terms: D000818:Animals; D000890:Anti-Infective Agents / Q000737:chemistry / Q000302:isolation & purification / Q000378:metabolism / Q000627:therapeutic use; D000959:Antihypertensive Agents / Q000737:chemistry / Q000302:isolation & purification / Q000378:metabolism / Q000627:therapeutic use; D000970:Antineoplastic Agents / Q000737:chemistry / Q000302:isolation & purification / Q000378:metabolism / Q000627:therapeutic use; D000975:Antioxidants / Q000737:chemistry / Q000302:isolation & purification / Q000378:metabolism / Q000627:therapeutic use; D059001:Aquatic Organisms / Q000378:metabolism; D048271:Chitosan / Q000737:chemistry / Q000378:metabolism*; D019587:Dietary Supplements; D006293:Health Promotion; D006801:Humans; D006868:Hydrolysis; D009844:Oligosaccharides / Q000737:chemistry / Q000302:isolation & purification / Q000378:metabolism* / Q000627:therapeutic use*
chemical_list: D000890:Anti-Infective Agents; D000959:Antihypertensive Agents; D000970:Antineoplastic Agents; D000975:Antioxidants; D009844:Oligosaccharides; D048271:Chitosan