title: [Antibiotic resistance of Gardnerella vaginalis isolated from cases of bacterial vaginosis].
abstract: BACKGROUND
  Gardnerella vaginalis is one of the dominant etiological factors related to bacterial vaginosis. Literature offers a growing number of reports revealing there appear Gardnerella vaginalis strains increasingly resistant to metronidazole.
  
  
  OBJECTIVE
  The aim of this study was to determine the susceptibility of Gardnerella vaginalis strains isolated from women with bacterial vaginosis to metronidazole, clindamycin and amoxicillin/clavulanic acid.
  
  
  METHODS
  The investigation was performed on collection of 67 Gardnerella vaginalis strains isolated from the group of 604 women participating in the study Antibiotic sensitivity of strains was verified by E-test method (BioMerieux). Interpretation of results was performed in accordance with EUCAST criteria.
  
  
  RESULTS
  All tested strains, apart from one, were sensitive to clindamycin and amoxicillin/clavulanic acid. The results of susceptibility test to metronidazole indicated that 68.7% (46 out of 67 strains) were resistant to this antibiotic, while all of them were sensitive to both clindamycin and amoxicillin/clavulanic acid.
  
  
  CONCLUSIONS
  Near future may bring the need to change the treatment regimen of bacterial vaginosis.
authors.affiliation: Katedra Mikrobiologii Collegium Medicum Uniwersytetu Jagiellońskiego w Krakowie, Polska. atomusiak@student.cm-uj.krakow.pl
authors.forename: Anna
authors.initials: A
authors.lastname: Tomusiak
authors.forename: Magdalena
authors.initials: M
authors.lastname: Strus
authors.forename: Piotr Bogumił
authors.initials: PB
authors.lastname: Heczko
mesh_terms: D000282:Administration, Intravaginal; D000284:Administration, Oral; D000328:Adult; D019980:Amoxicillin-Potassium Clavulanate Combination / Q000494:pharmacology; D000890:Anti-Infective Agents / Q000494:pharmacology*; D015373:Bacterial Typing Techniques; D002981:Clindamycin / Q000494:pharmacology; D024881:Drug Resistance, Bacterial; D005260:Female; D006194:Gardnerella vaginalis / Q000187:drug effects* / Q000302:isolation & purification; D006801:Humans; D008795:Metronidazole / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D011044:Poland / Q000453:epidemiology; D014621:Vagina / Q000382:microbiology; D016585:Vaginosis, Bacterial / Q000188:drug therapy* / Q000382:microbiology*; D055815:Young Adult
chemical_list: D000890:Anti-Infective Agents; D008795:Metronidazole; D002981:Clindamycin; D019980:Amoxicillin-Potassium Clavulanate Combination