title: Small GTPases and formins in mammalian oocyte maturation: cytoskeletal organizers.
abstract: The maturation process of mammalian oocytes accompanies an extensive rearrangement of the cytoskeleton and associated proteins. As this process requires a delicate interplay between the cytoskeleton and its regulators, it is often targeted by various external and internal adversaries that affect the congression and/or segregation of chromosomes. Asymmetric cell division in oocytes also requires specific regulators of the cytoskeleton, including formin-2 and small GTPases. Recent literature providing clues regarding how actin filaments and microtubules interact during spindle migration in mouse oocytes are highlighted in this review.
authors.affiliation: Department of Biomedical Science & Technology, Institute of Biomedical Science & Technology, Research Center for Transcription Control, Konkuk University, Seoul, Korea.
authors.forename: Sojung
authors.initials: S
authors.lastname: Kwon
authors.forename: Hyunjung J
authors.initials: HJ
authors.lastname: Lim