title: Statistical agreement of left ventricle measurements using cardiac magnetic resonance and 2D echocardiography in ischemic heart failure.
abstract: BACKGROUND
  The aim of this study was to compare cardiac magnetic resonance imaging (CMR) with 2-dimensional echocardiography (2D echo) in the assessment of left ventricle (LV) function parameters and mass in patients with ischemic heart disease and severely depressed LV function. Although 2D echo is commonly used to assess LV indices, CMR is the state-of-the-art technique. Agreement between these 2 methods in these patients has not been well established.
  
  
  METHODS
  LV indexed end systolic and diastolic volumes (EDVi and ESVi), indexed mass (LVMi) and ejection fraction (EF) were assessed in 67 patients (12 women), using 2D echo and CMR.
  
  
  RESULTS
  According to statistical analysis (Bland-Altman), 2D echo underestimated LV EDV and ESV and overestimated EF and LVMi compared to CMR. The highest correlation between 2D echo and CMR was found for EDVi (R2=0.73, p<0.0001) and ESVi (R2=0.69, p<0.0001) and the lowest for EF (R2=0.21, p=0.001) and LVMi (R2=0.20, p=0.002). The maximal differences between 2D echo and CMR were found for highest mesurements of LV volumes and mass, and for lowest EF values.
  
  
  CONCLUSIONS
  There is moderate to strong correlation between CMR and 2D echo in the assessment of LV function parameters and mass in patients with ischemic heart failure. Between-method agreement depends on the degree of LV dysfunction. The results of assessment of the severely damaged LV obtained by the use of 2D echo should be interpreted with caution.
authors.affiliation: Department of Radiology and Nuclear Medicine, Medical University of Silesia, Katowice, Poland. kgruszczynska@poczta.onet.pl
authors.forename: Katarzyna
authors.initials: K
authors.lastname: Gruszczyńska
authors.forename: Lukasz J
authors.initials: LJ
authors.lastname: Krzych
authors.forename: Krzysztof S
authors.initials: KS
authors.lastname: Gołba
authors.forename: Jolanta
authors.initials: J
authors.lastname: Biernat
authors.forename: Tomasz
authors.initials: T
authors.lastname: Roleder
authors.forename: Marek A
authors.initials: MA
authors.lastname: Deja
authors.forename: Piotr
authors.initials: P
authors.lastname: Ulbrych
authors.forename: Marcin
authors.initials: M
authors.lastname: Malinowski
authors.forename: Piotr
authors.initials: P
authors.lastname: Janusiewicz
authors.forename: Stanisław
authors.initials: S
authors.lastname: Woś
authors.forename: Jan
authors.initials: J
authors.lastname: Baron
mesh_terms: D000368:Aged; D004452:Echocardiography / Q000379:methods*; D005260:Female; D006352:Heart Ventricles / Q000000981:diagnostic imaging / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000000981:diagnostic imaging / Q000473:pathology*