title: Bismuth nitrate pentahydrate-induced novel nitration of eugenol.
abstract: BACKGROUND
  Eugenol, the main constituent of clove oil possesses a number of medicinal activities. To enhance the medicinal property, structural modification is required. On the other hand, bismuth nitrate pentahydrate has been established as an excellent eco-friendly nitrating agent for several classes of organic compounds.
  
  
  RESULTS
  Bismuth nitrate pentahydrate-induced nitration of eugenol has been investigated very thoroughly. Twenty five different conditions have been studied. The microwave-induced solvent-free reaction has been identified as the best condition.
  
  
  CONCLUSIONS
  Spectral analyses confirm that 5-nitroeugenol is the sole product in all the cases. No oxidized or isomerized product could be detected.
authors.affiliation: Department of Chemistry, The University of Texas-Pan American, 1201, West University Drive, Edinburg, TX 78539, USA. banik@utpa.edu.
authors.forename: Luis
authors.initials: L
authors.lastname: Canales
authors.forename: Debasish
authors.initials: D
authors.lastname: Bandyopadhyay
authors.forename: Bimal K
authors.initials: BK
authors.lastname: Banik