title: Malignant granular cell tumor of the posterior mediastinum with dissemination.
abstract: A 66-year-old man presented with severe back pain. Imaging studies revealed a well-circumscribed mass in the left posterior mediastinum. Because of pleural dissemination observed at thoracotomy, palliative resection was performed to relieve his back pain. Histologically, the tumor was composed of cells with large eosinophilic and granular cytoplasm, which were strongly positive for S-100. Mediastinal malignant granular cell tumor with pleural dissemination is extremely unusual.
authors.affiliation: Division of Thoracic Surgery, Center for Innovative Oncology, National Cancer Center Hospital East, Kashiwa, Chiba, Japan. manakao@east.ncc.go.jp
authors.forename: Masayuki
authors.initials: M
authors.lastname: Nakao
authors.forename: Tomoyuki
authors.initials: T
authors.lastname: Hishida
authors.forename: Genichiro
authors.initials: G
authors.lastname: Ishii
authors.forename: Junji
authors.initials: J
authors.lastname: Yoshida
authors.forename: Mitsuyo
authors.initials: M
authors.lastname: Nishimura
authors.forename: Kanji
authors.initials: K
authors.lastname: Nagai
mesh_terms: D000368:Aged; D016586:Granular Cell Tumor / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008297:Male; D008479:Mediastinal Neoplasms / Q000473:pathology* / Q000601:surgery; D008482:Mediastinum / Q000473:pathology / Q000601:surgery*; D010997:Pleural Neoplasms / Q000473:pathology / Q000556:secondary / Q000601:surgery*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome