title: [Study for the histopathologic change of ethmoid bone in patients with chronic rhinosinusitis and its correlation factors].
abstract: OBJECTIVE
  To investigate the histopathologic changes of ethmoid bone and its correlation with clinical types of chronic rhinosinusitis (CRS).
  
  
  METHODS
  All ethmoid bones and mucosa from 180 patients with CRS after endoscopic sinus surgery were collected for histopathologic detection with HE staining. The number and the rate of cases were counted according to different histopathologic types. To analyze the correlation between ethmoid bones and clinical types of CRS, mucosal pathologic change, the CT-scanning types of sinusitis, the course of disease as well as operational history.
  
  
  RESULTS
  The ethmoid bone of all patients had varying degrees of histopathologic changes. There were 5 cases (2.78%) in stage I, 38 cases (21.11%) in stage II, 71 cases (39.44%) in stage III, and 66 cases (36.67%) in stage NIV. The histopathologic changes of ethmoid bone varied in different clinical types. In type I, there were 5 cases (8.33%) in stage I, 33 cases (55.00%) in stage II, 15 cases (25.00%) in stage III, and 7 cases (11.67%) in stage NV. In type I, there were 5 cases (8.33%) in stage II, 37 cases (61.67%) in stage mI, and 18 cases (30.00%) in stage NV. In type III, there were 19 cases (31.67%) in stage III, and 41 cases (68.33%) in stage NV. All histopathologic changes of ethmoid bone were statistically correlated (P < 0.01) with clinical types of CRS, pathologic mucosal change, the CT-scanning types of sinusitis, the course of disease as well as operational history.
  
  
  CONCLUSIONS
  Almost all patients with CRS manifest different-degrees of histopathologic changes, which are correlated with the clinical types of CRS, pathologic mucosal change, the CT-scanning types, the course of disease as well as operational history.
authors.affiliation: Department of Otorhinolaryngology, People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, 530021, China.
authors.forename: Fengzhu
authors.initials: F
authors.lastname: Tang
authors.forename: Shenhong
authors.initials: S
authors.lastname: Qu
authors.forename: Jianping
authors.initials: J
authors.lastname: Liang
authors.forename: Haiming
authors.initials: H
authors.lastname: Wei
authors.forename: Qiutian
authors.initials: Q
authors.lastname: Lu
authors.forename: Xiangzhen
authors.initials: X
authors.lastname: Zhou
authors.forename: Tao
authors.initials: T
authors.lastname: Wang
authors.forename: Yuemin
authors.initials: Y
authors.lastname: Zhang
mesh_terms: D000293:Adolescent; D000328:Adult; D002908:Chronic Disease; D005004:Ethmoid Bone / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009297:Nasal Mucosa / Q000000981:diagnostic imaging / Q000473:pathology*; D011859:Radiography; D012852:Sinusitis / Q000000981:diagnostic imaging / Q000473:pathology*; D055815:Young Adult