title: Programmable protein-protein conjugation via DNA-based self-assembly.
abstract: Protein molecules were precisely arrayed on a designable DNA scaffold close to each other using a DNA aptamer. By adding a chemical cross-linker, the neighboring protein molecules were effectively and covalently cross-linked to each other without losing their activities.
authors.affiliation: Department of Applied Chemistry, Graduate School of Engineering, Kyushu University, 744 Moto-oka, Fukuoka 819-0395, Japan.
authors.forename: Josui
authors.initials: J
authors.lastname: Shimada
authors.forename: Tatsuo
authors.initials: T
authors.lastname: Maruyama
authors.forename: Momoko
authors.initials: M
authors.lastname: Kitaoka
authors.forename: Hisao
authors.initials: H
authors.lastname: Yoshinaga
authors.forename: Koji
authors.initials: K
authors.lastname: Nakano
authors.forename: Noriho
authors.initials: N
authors.lastname: Kamiya
authors.forename: Masahiro
authors.initials: M
authors.lastname: Goto
mesh_terms: D004247:DNA / Q000138:chemical synthesis* / Q000737:chemistry; D011485:Protein Binding; D013917:Thrombin / Q000737:chemistry*
chemical_list: D004247:DNA; D013917:Thrombin