title: Draft genome sequence of marine Streptomyces sp. strain W007, which produces angucyclinone antibiotics with a benz[a]anthracene skeleton.
abstract: A series of angucyclinone antibiotics have been isolated from marine Streptomyces sp. strain W007 and identified. Here, a draft genome sequence of Streptomyces sp. W007 is presented. The genome contains an intact biosynthetic gene cluster for angucyclinone antibiotics, which provides insight into the combinatorial biosynthesis of angucyclinone antibiotics produced by marine streptomycetes.
authors.affiliation: Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences, Yantai, China. sqin@yic.ac.cn
authors.forename: Song
authors.initials: S
authors.lastname: Qin
authors.forename: Hongyu
authors.initials: H
authors.lastname: Zhang
authors.forename: Fuchao
authors.initials: F
authors.lastname: Li
authors.forename: Benwei
authors.initials: B
authors.lastname: Zhu
authors.forename: Huajun
authors.initials: H
authors.lastname: Zheng
mesh_terms: D000880:Anthraquinones / Q000737:chemistry / Q000378:metabolism; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000378:metabolism; D001551:Benz(a)Anthracenes / Q000378:metabolism; D053898:Biosynthetic Pathways / Q000235:genetics; D004269:DNA, Bacterial / Q000737:chemistry* / Q000235:genetics*; D005798:Genes, Bacterial; D016680:Genome, Bacterial; D019015:Geologic Sediments / Q000382:microbiology; D008969:Molecular Sequence Data; D005810:Multigene Family; D017422:Sequence Analysis, DNA; D013302:Streptomyces / Q000235:genetics* / Q000302:isolation & purification / Q000378:metabolism
chemical_list: D000880:Anthraquinones; D000900:Anti-Bacterial Agents; D001551:Benz(a)Anthracenes; D004269:DNA, Bacterial; C510997:angucyclinone; C030935:benz(a)anthracene