title: Prevalence of Subclinical Hypothyroidism among Patients with Acute Myocardial Infarction.
abstract: Introduction. Subclinical hypothyroidism (SCH) is defined as a serum thyroid-stimulating hormone (TSH) level above the upper limit of normal despite normal levels of serum free thyroxine. There is growing evidence that SCH is associated with increased cardiovascular risk. We tried to investigate prevalence of SCH in acute myocardial infarction patients. Methods and Results. We evaluate free T3, free T4, and TSH levels of 604 patients (age 58.4) retrospectively, who have been admitted to the coronary intensive care unit between years 2004-2009 with the diagnosis of ST elevation (STEMI) or non-ST elevation acute myocardial infarction (NSTEMI). Mild subclinical hypothyroidism (TSH 4.5 to 9.9 mU/l) was present in 54 (8.94%) participants and severe subclinical hypothyroidism (TSH 10.0 to 19.9 mU/l) in 11 (1.82%). So 65 patients (10.76%) had TSH levels between 4.5 and 20. Conclusions. In conclusion, 65 patients (10.76%) had TSH levels between 4.5 and 20 in our study, and it is a considerable amount. Large-scale studies are needed to clarify the effects of SCH on myocardial infarction both on etiologic and prognostic grounds.
authors.affiliation: Cardiology Clinic, Bağcılar Education and Research Hospital, Bagcilar, 34200 Istanbul, Turkey.
authors.forename: Okuyan
authors.initials: O
authors.lastname: Ertugrul
authors.forename: Uslu
authors.initials: U
authors.lastname: Ahmet
authors.forename: Enhos
authors.initials: E
authors.lastname: Asim
authors.forename: Hepgul E
authors.initials: HE
authors.lastname: Gulcin
authors.forename: Ayca
authors.initials: A
authors.lastname: Burak
authors.forename: Avsar
authors.initials: A
authors.lastname: Murat
authors.forename: Yildiz S
authors.initials: YS
authors.lastname: Sezai
authors.forename: Halil Ibrahim
authors.initials: HI
authors.lastname: Biter
authors.forename: Dinckal M
authors.initials: DM
authors.lastname: Hakan