title: Glyphosate, alachor and maleic hydrazide have genotoxic effect on Trigonella foenum-graecum L.
abstract: In the present study effects of herbicides glyphosate (GP), alachlor (AL) and maleic hydrazide (MH) is studied on mitotic cells of Trigonella foenum-graecum L. Seeds of T. foenum-graecum L. treated with a series of concentrations ranging from 0.1%, 0.2%, 0.3%, 0.4% and 0.5% for 1, 2 and 6 h and their effect on mitotic index and chromosomal aberrations was studied. The results indicate that these herbicides reduced mitotic index in dose-dependent manner. In addition, increase in the percentage of abnormal mitotic plates was observed in herbicide treated groups which was both concentration and time dependent. Commonly observed abnormalities were c-mitosis, laggards, bridges, stickiness, c-anaphase, precocious separation, un-equal distribution and fragments. The result of the present investigation indicates that commonly used herbicides GP, AL and MH have significant genotoxic effect on T. foenum-graecum plant.
authors.affiliation: Department of Botany, Saifia Sciences Postgraduate College, Bhopal, Madhya Pradesh, India. guddank@rediffmail.com
authors.forename: Sazada
authors.initials: S
authors.lastname: Siddiqui
authors.forename: Mukesh K
authors.initials: MK
authors.lastname: Meghvansi
authors.forename: Shoukat Saeed
authors.initials: SS
authors.lastname: Khan
mesh_terms: D000081:Acetamides / Q000633:toxicity*; D002869:Chromosome Aberrations / Q000139:chemically induced; D005998:Glycine / Q000031:analogs & derivatives* / Q000633:toxicity; D006540:Herbicides / Q000633:toxicity*; D008300:Maleic Hydrazide / Q000633:toxicity*; D008938:Mitosis / Q000187:drug effects; D009153:Mutagens / Q000633:toxicity*; D029910:Trigonella / Q000187:drug effects* / Q000235:genetics / Q000254:growth & development; D000097797:Glyphosate
chemical_list: D000081:Acetamides; D005998:Glycine; D006540:Herbicides; D008300:Maleic Hydrazide; D009153:Mutagens; D000097797:Glyphosate; C000188:alachlor