title: Interhemispheric and quadrigeminal cysts.
abstract: BACKGROUND
  Interhemispheric and quadrigeminal cysts are rare lesions, similar in their propensity to present in young babies and to be associated with other central nervous system malformations, such as corpus callosum agenesia, holoprosencephaly, encephalocele, and neuronal heterotopias. Recently endoscopy has become increasingly popular in the treatment of arachnoid cysts, but experience with cysts located in the interhemispheric fissure and in the quadrigeminal cistern is limited.
  
  
  METHODS
  This study reviews the specific anatomy of interhemispheric and quadrigeminal cysts and their relationship with the ventricular system and subarachnoid cisterns to select the most appropriated treatment. It also reviews the literature on endoscopic treatment of interhemispheric and quadrigeminal cysts.
  
  
  RESULTS
  Interhemispheric and quadrigeminal cysts are not homogeneous, they have different extensions toward surrounding regions. In most cases it is presented as an area of contiguity between the cyst and ventricular system and/or subarachnoid cisterns, making endoscopic treatment feasible. The success rate for endoscopic treatment is not different from that reported in large series of arachnoid cysts elsewhere.
  
  
  CONCLUSIONS
  Endoscopic treatment should be considered the first-line option in the treatment of such lesions, even if some complications, such as subdural collections due to thinness of the cerebral mantle or subcutaneous CSF collections due to multifactorial associated hydrocephalus, must be expected.
authors.affiliation: Department of Pediatric Neurosurgery, Santobono-Paulipon Pediatric Hospital, Naples, Italy.
authors.forename: Pietro
authors.initials: P
authors.lastname: Spennato
authors.forename: Claudio
authors.initials: C
authors.lastname: Ruggiero
authors.forename: Ferdinando
authors.initials: F
authors.lastname: Aliberti
authors.forename: Maria Consiglio
authors.initials: MC
authors.lastname: Buonocore
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Trischitta
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Cinalli
mesh_terms: D016080:Arachnoid Cysts / Q000601:surgery; D001927:Brain Diseases / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery*; D001932:Brain Neoplasms / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery*; D002552:Cerebral Ventricles / Q000473:pathology / Q000601:surgery; D002557:Cerebrospinal Fluid Shunts; D003560:Cysts / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery*; D004724:Endoscopy / Q000379:methods*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008279:Magnetic Resonance Imaging; D009421:Nervous System Malformations / Q000473:pathology / Q000601:surgery*; D044583:Neuroendoscopy; D019635:Neurosurgical Procedures / Q000379:methods*; D003336:Tectum Mesencephali / Q000473:pathology*; D016896:Treatment Outcome