title: Exacerbation of idiopathic paroxysmal kinesigenic dyskinesia in remission state caused by secondary hypoparathyroidism with hypocalcemia after thyroidectomy: evidence for ion channelopathy.
abstract: Most reported cases of paroxysmal kinesigenic dyskinesia (PKD) are idiopathic or familial; however, hypoparathyroidism is another unusual cause of secondary PKD. The pathomechanism of PKD remains poorly understood, and the association between idiopathic and secondary PKD remains an enigma, and has yet to be clearly elucidated. We recently encountered a patient with idiopathic PKD whose symptoms were aggravated by secondary hypoparathyroidism with hypocalcemia after having undergone a thyroidectomy. The patient's paroxysms were ameliorated by the normalization of serum calcium levels. The results discussed herein may provide support for the hypothesis that PKD is associated with neuronal ion regulation.
authors.affiliation: Department of Neurology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Republic of Korea.
authors.forename: Dongkwan
authors.initials: D
authors.lastname: Jin
authors.forename: Won Tae
authors.initials: WT
authors.lastname: Yoon
authors.forename: Bum Chun
authors.initials: BC
authors.lastname: Suh
authors.forename: Heui-Soo
authors.initials: HS
authors.lastname: Moon
authors.forename: Pil-Wook
authors.initials: PW
authors.lastname: Chung
authors.forename: Yong Bum
authors.initials: YB
authors.lastname: Kim
mesh_terms: D000328:Adult; D002118:Calcium / Q000097:blood; D053447:Channelopathies / Q000150:complications; D002819:Chorea / Q000209:etiology*; D004421:Dystonia; D006801:Humans; D006996:Hypocalcemia / Q000209:etiology*; D007011:Hypoparathyroidism / Q000209:etiology*; D008297:Male; D012074:Remission Induction; D013965:Thyroidectomy / Q000009:adverse effects*
chemical_list: D002118:Calcium