title: Malignant melanoma: advances in diagnosis, prognosis, and treatment.
abstract: The detection of cutaneous melanoma still largely relies on clinical suspicion, skin biopsy, and histopathologic evaluation. New technologies are being evaluated to bypass the skin biopsy in the detection of melanoma. The quest for reliable biomarkers, with respect to subclinical detection, prognosis, and predicting treatment response, is longstanding and ongoing. New therapies have been developed for metastatic disease, including targeted small molecule inhibitors as well as immune modulators.
authors.affiliation: Department of Dermatology, Cutaneous Oncology, Stanford University School of Medicine, Stanford, CA 94305, USA. krathen@stanford.edu
authors.forename: Michael
authors.initials: M
authors.lastname: Krathen
mesh_terms: D000911:Antibodies, Monoclonal / Q000627:therapeutic use; D000970:Antineoplastic Agents / Q000627:therapeutic use; D014408:Biomarkers, Tumor / Q000032:analysis*; D001706:Biopsy; D006801:Humans; D008545:Melanoma / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D011379:Prognosis; D012867:Skin / Q000473:pathology; D012878:Skin Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology
chemical_list: D000911:Antibodies, Monoclonal; D000970:Antineoplastic Agents; D014408:Biomarkers, Tumor