title: First 100 early endometrial cancer cases treated with laparoendoscopic single-site surgery: a multicentric retrospective study.
abstract: OBJECTIVE
  We sought to assess feasibility and perioperative outcomes for laparoendoscopic single-site surgery (LESS) in early endometrial cancer.
  
  
  METHODS
  This was a retrospective multicentric study of 100 early endometrial cancer cases undergoing LESS from July 2009 through July 2011.
  
  
  RESULTS
  All patients underwent total hysterectomy and bilateral salpingo-oophorectomy by LESS. Pelvic and paraaortic lymphadenectomy were performed in 48 and 27 patients, respectively. A median of 16 pelvic lymph nodes (range, 1-33) and 7 paraaortic lymph nodes (range, 2-28) were retrieved. Both median operative time (129 minutes; range, 45-321) and estimated blood loss (70 mL; range, 10-500) were greater when staging lymphadenectomy was performed (P values = .001). Four intraoperative and 4 postoperative complications were observed. Conversion to standard laparoscopy and laparotomy was necessary for completion of 1 case each. Patients responded positively regarding cosmetic result and minimal postoperative pain control.
  
  
  CONCLUSIONS
  LESS further minimizes the invasive nature of surgery and is feasible for treatment of early-stage endometrial cancer.
authors.affiliation: Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Catholic University of the Sacred Heart, Rome, Italy. anna.fagotti@rm.unicatt.it
authors.forename: Anna
authors.initials: A
authors.lastname: Fagotti
authors.forename: David M
authors.initials: DM
authors.lastname: Boruta
authors.forename: Giovanni
authors.initials: G
authors.lastname: Scambia
authors.forename: Francesco
authors.initials: F
authors.lastname: Fanfani
authors.forename: Amelia
authors.initials: A
authors.lastname: Paglia
authors.forename: Pedro F
authors.initials: PF
authors.lastname: Escobar
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016063:Blood Loss, Surgical; D016889:Endometrial Neoplasms / Q000601:surgery*; D005260:Female; D006801:Humans; D007044:Hysterectomy / Q000379:methods*; D010535:Laparoscopy / Q000379:methods*; D008197:Lymph Node Excision / Q000379:methods; D008875:Middle Aged; D017060:Patient Satisfaction; D011183:Postoperative Complications / Q000517:prevention & control; D012189:Retrospective Studies; D058994:Salpingectomy / Q000379:methods