title: [About development of chlamydia multiple organ lesions after primary ocular infection in experiment].
abstract: Chlamidia spp. are obligate intracellular pathogens that cause a variety of diseases in humans and animals. Their generalization was proved as hematogenic spreading from the urogenital (C. trachomatis) and the respiratory (C. pneumoniae) systems. The goal was to investigate the possibility of C. trachomatis infection spreading from the primary ocular gate. 6 animals were infected by instillation in the conjunctival sack, subconjunctival and intravitreal injections of C. thachomatis culture. C. trachomatis was detected by direct immunofluorescence method in the retina, retinal pigment epithelium, choroid, brain, the pancreas, the prostate gland and the urethra after primary ocular infection. The results of our study have proved the opportunity of C. trachomatis to cause polyorganic contamination.
authors.forename: E V
authors.initials: EV
authors.lastname: Boĭko
authors.forename: A L
authors.initials: AL
authors.lastname: Pozniak
authors.forename: I V
authors.initials: IV
authors.lastname: Nuralova
authors.forename: D S
authors.initials: DS
authors.lastname: Mal'tsev
authors.forename: A A
authors.initials: AA
authors.lastname: Suetov
authors.forename: V S
authors.initials: VS
authors.lastname: Ageev
authors.forename: D Iu
authors.initials: DIu
authors.lastname: Iakushev
mesh_terms: D000818:Animals; D016470:Bacteremia / Q000382:microbiology* / Q000473:pathology; D001921:Brain / Q000382:microbiology / Q000473:pathology; D002690:Chlamydia Infections / Q000382:microbiology* / Q000473:pathology; D002692:Chlamydia trachomatis / Q000302:isolation & purification*; D003941:Diagnostic Techniques, Ophthalmological; D004195:Disease Models, Animal; D015818:Eye Infections, Bacterial / Q000382:microbiology* / Q000473:pathology; D008297:Male; D008856:Microscopy, Fluorescence; D010179:Pancreas / Q000382:microbiology / Q000473:pathology; D011467:Prostate / Q000382:microbiology / Q000473:pathology; D011817:Rabbits; D014521:Urethra / Q000382:microbiology / Q000473:pathology