title: Vasculitic neuropathy associated with minocycline use.
abstract: BACKGROUND
  Minocycline is an antibiotic used for the treatment of acne. It has been associated with several autoimmune syndromes, including drug-induced lupus, autoimmune hepatitis, and vasculitis.
  
  
  RESULTS
  We report a case of a 28-year-old previously healthy woman who developed a left sciatic mononeuropathy 2 weeks after starting minocycline for acne. Magnetic resonance imaging studies supported the localization. A biopsy of the left sural nerve revealed acute nerve large arteriole necrotizing vasculitis. Her condition improved after the withdrawal of minocycline and a course of treatment with methylprednisolone.
  
  
  CONCLUSIONS
  This case provides further evidence that minocycline may induce a nonsystemic necrotizing vasculitis.
authors.affiliation: Department of Neurological Sciences, University of Nebraska Medical Center, Omaha, NE 68198-2045, USA. pthaiset@unmc.edu
authors.forename: Pariwat
authors.initials: P
authors.lastname: Thaisetthawatkul
authors.forename: Robert
authors.initials: R
authors.lastname: Sundell
authors.forename: Carrie E
authors.initials: CE
authors.lastname: Robertson
authors.forename: Peter J
authors.initials: PJ
authors.lastname: Dyck
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008911:Minocycline / Q000009:adverse effects*; D020422:Mononeuropathies / Q000139:chemically induced* / Q000188:drug therapy; D020426:Sciatic Neuropathy / Q000139:chemically induced* / Q000188:drug therapy; D016896:Treatment Outcome; D014657:Vasculitis / Q000139:chemically induced* / Q000188:drug therapy
chemical_list: D000900:Anti-Bacterial Agents; D008911:Minocycline