title: Tick-borne encephalitis virus-neutralizing antibodies in different immunoglobulin preparations.
abstract: Patients with primary immunodeficiency (PIDs) depend on the presence of a variety of antibody specificities in intravenous immunoglobulin (IVIG). Using the tick-borne encephalitis virus (TBEV), geographic variability in IVIG antibody content was shown. Care should therefore be exercised when treating PIDs in a given geography, as only locally sourced plasma contains the antibody specificities against the circulating pathogens in the given locality.
authors.affiliation: Global Pathogen Safety, Baxter BioScience, Vienna, Austria.
authors.forename: Philip O
authors.initials: PO
authors.lastname: Rabel
authors.forename: Christina B
authors.initials: CB
authors.lastname: Planitzer
authors.forename: Maria R
authors.initials: MR
authors.lastname: Farcet
authors.forename: Thomas R
authors.initials: TR
authors.lastname: Kreil
mesh_terms: D057134:Antibodies, Neutralizing / Q000032:analysis*; D000914:Antibodies, Viral / Q000032:analysis*; D004669:Encephalitis Viruses, Tick-Borne / Q000276:immunology*; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000276:immunology*; D007153:Immunologic Deficiency Syndromes / Q000628:therapy
chemical_list: D057134:Antibodies, Neutralizing; D000914:Antibodies, Viral; D016756:Immunoglobulins, Intravenous