title: Utility of Dermoscopy before and after Laser Irradiation in Port Wine Stains.
abstract: BACKGROUND
  Port wine stains (PWSs) are commonly treated with pulsed dye laser (PDL) as a standard therapy. However, it is not easy to predict the minimal effective dose in the first treatment session.
  
  
  OBJECTIVE
  The aim of this study was to assess whether dermoscopic findings before and after laser irradiation corresponded with the clinical improvement of PWS in patients undergoing PDL therapy.
  
  
  METHODS
  Seven untreated PWSs in 6 patients (a male and 5 females), who presented to our hospital between May 2008 to January 2010, were assessed in this study. The mean age was 36.3 years, ranging from 14 to 57 years. A PDL with a wavelength of 585 nm and a spot size of 7 mm was used. Before and after test irradiation, patients underwent dermoscopy and clinical photography, and we assessed whether the dermoscopic findings corresponded with clinical improvement after 3 months.
  
  
  RESULTS
  There were no obvious differences observed in the clinical photographs between each test level immediately after irradiation. However, dermoscopic photographs showed differences as the irradiated energy increased. These changes corresponded to the clinical improvement after 3 months.
  
  
  CONCLUSIONS
  Our study indicates that the minimal effective fluence can be predicted by observing dermoscopic change immediately after irradiation. We think that examining the dermoscopic findings immediately after irradiation allows the laser surgeon to predict the minimal effective fluence and this prevents adverse effects of the skin.
authors.affiliation: Department of Plastic and Reconstructive Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan.
authors.forename: Makiko
authors.initials: M
authors.lastname: Shirakawa
authors.forename: Toshiyuki
authors.initials: T
authors.lastname: Ozawa
authors.forename: Satoki
authors.initials: S
authors.lastname: Wakami
authors.forename: Masamitsu
authors.initials: M
authors.lastname: Ishii
authors.forename: Teruichi
authors.initials: T
authors.lastname: Harada