title: Asymptomatic bacteriurea among pregnant women visiting Nepal Medical College Teaching Hospital, Kathmandu, Nepal.
abstract: Urinary tract infection is the commonest bacterial infection in pregnancy. The overall incidence is 5.0-10.0% of all pregnancy. During pregnancy bacterial growth is favoured by increased urinary content of glucose, aminoacids and other nutrients. Other factors responsible for infection are basically related to hormonal effect and mechanical factors. Prolonged stasis of urine in urinary bladder favours growth of micro organism, relaxation of vesico-ureteric junction leads to reflux of urine from bladder to ureter and later up to renal pelvis and later can affect the renal parenchyma affecting the function of kidneys. In addition, some maternal defense mechanism are less effective during pregnancy. Bacteriuria either asymptomatic (5.0%) or symptomatic is common in pregnancy, if left untreated, asymptomatic bacteriuria will lead to acute pyelonephritis in 20.0-30.0%. This may result in abortion, premature delivery, low birth baby and even still birth. About 12.0% of antenatal admission are sepsis due to pyelonephritis. Keeping in mind that UTI in pregnancy leads to increase in maternal morbidity as well as neonatal morbidity and mortality. In this prospective study all asymptomatic consecutive antenatal women were included 200 from each trimester with total of 600 in number to see the incidence in different trimester, most prevalent organisms and it's sensitivity. They were followed up till delivery to see the incidence of asymptomatic bacteriurea in different trimester and its outcome in terms of type of delivery, baby weight, apgar score given at the time of birth and hospital admission for morbidity.
authors.affiliation: Department of OBS/Gynae, Nepal Medical College and Teaching Hospital, Jorpati, Kathmandu, Nepal. ritakhanal2@yahoo.com
authors.forename: R
authors.initials: R
authors.lastname: Marahatta
authors.forename: B Acharya
authors.initials: BA
authors.lastname: Dhungel
authors.forename: P
authors.initials: P
authors.lastname: Pradhan
authors.forename: S K
authors.initials: SK
authors.lastname: Rai
authors.forename: D Roy
authors.initials: DR
authors.lastname: Choudhury
mesh_terms: D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D000892:Anti-Infective Agents, Urinary / Q000008:administration & dosage; D001437:Bacteriuria / Q000453:epidemiology*; D005260:Female; D005839:Gentamicins / Q000008:administration & dosage; D006784:Hospitals, Teaching; D006801:Humans; D015994:Incidence; D008826:Microbial Sensitivity Tests; D009390:Nepal / Q000453:epidemiology; D009582:Nitrofurantoin / Q000008:administration & dosage; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000453:epidemiology*; D011446:Prospective Studies
chemical_list: D000900:Anti-Bacterial Agents; D000892:Anti-Infective Agents, Urinary; D005839:Gentamicins; D009582:Nitrofurantoin