title: Drug trapping and delivery for Alzheimer's diagnosis.
abstract: In this investigation, a new design based on a PANDA ring resonator as an optical trapping tool for tangle protein, molecular motor storage, and delivery is proposed. The optical vortices are generated and the trapping mechanism is controlled in the same way as the conventional optical tweezers. The trapping force is produced by a combination of the gradient field and scattering photons. The required molecular volume is trapped and moved dynamically within the molecular network. The tangle protein and molecular motor can be transported and delivered to the required destinations for Alzheimer's diagnosis by molecular buffer and bus network.
authors.affiliation: Ibnu Sina Institute of Fundamental Science Studies, Nanotechnology Research Alliance,Universiti Teknologi Malaysia (UTM), Johor Bahru, Malaysia.
authors.forename: M A
authors.initials: MA
authors.lastname: Jalil
authors.forename: Surachart
authors.initials: S
authors.lastname: Kamoldilok
authors.forename: T
authors.initials: T
authors.lastname: Saktioto
authors.forename: C T
authors.initials: CT
authors.lastname: Ong
authors.forename: Preecha P
authors.initials: PP
authors.lastname: Yupapin
mesh_terms: D000544:Alzheimer Disease / Q000175:diagnosis*; D016229:Amyloid beta-Peptides / Q000737:chemistry / Q000378:metabolism*; D001369:Axons / Q000737:chemistry / Q000378:metabolism*; D002021:Buffers; D004578:Electron Spin Resonance Spectroscopy; D006801:Humans; D008870:Microtubules / Q000737:chemistry / Q000378:metabolism*; D020409:Molecular Motor Proteins / Q000737:chemistry / Q000378:metabolism*; D016874:Neurofibrillary Tangles / Q000378:metabolism*; D052898:Optical Tweezers; D021381:Protein Transport; D016875:tau Proteins / Q000737:chemistry / Q000378:metabolism*
chemical_list: D016229:Amyloid beta-Peptides; D002021:Buffers; D020409:Molecular Motor Proteins; D016875:tau Proteins