title: [Chemical studies on alkaloids of Chinese medicinal herbs Daphniphyllum macropodum].
abstract: OBJECTIVE
  To study the alkaloids of the Chinese medicinal herbs Daphniphyllum macropodum for in search for new bioactive substances.
  
  
  METHODS
  The CHCl3 extract of D. macropodum was subjected to repeated column chromatography on silica gel to afford four pure compounds (1-4). Their structures were determined on the basis of detailed spectroscopic analysis and comparison with the data reported in the literature.
  
  
  RESULTS
  The four known compounds were isolated and elucidated as Daphniphyllum alkaloids with different carbon skeletons, namely longistylumphylline A (1), deoxycalyciphylline B (2), daphnicyclidin B (3) and H (4), respectively.
  
  
  CONCLUSIONS
  All compounds were isolated from the titled plant for the first time. The discovery of daphnicyclidin B (3) and H (4) further confirmed the biogenetic relationship between the two compounds and the previously reported macropodumines A-C, found in the same plant.
authors.affiliation: Affiliated Hospital of Shandong Academy of Medical Sciences, Ji'nan 250031, China. he2008jinan@126.com
authors.forename: Xiuli
authors.initials: X
authors.lastname: He
authors.forename: Songhua
authors.initials: S
authors.lastname: Wang
authors.forename: Yanguo
authors.initials: Y
authors.lastname: Zhao
mesh_terms: D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification*; D004365:Drugs, Chinese Herbal / Q000032:analysis*; D019684:Magnoliopsida / Q000737:chemistry*
chemical_list: D000470:Alkaloids; D004365:Drugs, Chinese Herbal