title: Incidental finding of peripheral B-cell non-Hodgkin lymphoma, lymphocytic/CLL type, of the gallbladder in a patient with chronic cholecystitis.
abstract: Although lymphoma involvement of the gallbladder, especially by MALT and large-cell types, is rare, this possibility should be considered in patients with symptoms of acute cholecystitis. A cholecystectomy was performed in a 79-year-old male patient with a clinical diagnosis of chronic cholecystitis. Histologically, the specimen showed an incidental finding of a small lymphocytic lymphoma (CLL) by morphologic and immunophenotyping studies, subsequently confirmed with flow cytometric analysis of blood. During follow-up, multiple lymph node enlargement was detected. An axillary node, excised and submitted to our department, was positive for lymphoma involvement. The bone marrow was negative.
authors.affiliation: U.O. Anatomy, Pathological Histology and Cytodiagnostic Department, Padre Antero Micone Hospital, Genova, Italy. hossein.imenpour@asl3.liguria.it
authors.forename: H
authors.initials: H
authors.lastname: Imenpour
authors.forename: M
authors.initials: M
authors.lastname: Castagnola
authors.forename: G
authors.initials: G
authors.lastname: De Silva
authors.forename: S
authors.initials: S
authors.lastname: Zupo
authors.forename: M
authors.initials: M
authors.lastname: Truini
authors.forename: E
authors.initials: E
authors.lastname: Merlo
authors.forename: L
authors.initials: L
authors.lastname: Anselmi
mesh_terms: D000368:Aged; D015703:Antigens, CD / Q000378:metabolism; D014408:Biomarkers, Tumor / Q000378:metabolism; D002764:Cholecystitis / Q000150:complications / Q000473:pathology* / Q000601:surgery; D002908:Chronic Disease; D005706:Gallbladder Neoplasms / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D006801:Humans; D016130:Immunophenotyping; D033162:Incidental Findings; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D008198:Lymph Nodes / Q000473:pathology; D016393:Lymphoma, B-Cell / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D008297:Male; D009378:Neoplasms, Multiple Primary
chemical_list: D015703:Antigens, CD; D014408:Biomarkers, Tumor