title: Perioperative outcomes of total laparoendoscopic single-site hysterectomy versus total robotic hysterectomy in endometrial cancer patients: a multicentre study.
abstract: OBJECTIVE
  To compare the peri-operative outcomes between total laparo-endoscopic single-site (LESS) and robotic approaches for the staging and treatment of early stage endometrial cancer patients.
  
  
  METHODS
  A multicentre retrospective study involving three Italian gynaecological groups and one American centre. The peri-operative outcomes of LESS and robotic approach were compared in similar groups of patients, with regard to surgical outcomes and intra- and post-operative parameters and complications.
  
  
  RESULTS
  During the study period, 75 patients submitted to a total LESS hysterectomy and 75 patients received a total robotic hysterectomy. The median operative time - 122 versus 175 min (p=0.0001) - and the estimated blood loss - 50 versus 80 mL (p=0.03) - were slightly more favourable in the LESS group. The intra-operative complications were equally distributed (p=0.99); in the robotic group there were 4 (5.3%) post-operative grade IIIb complications versus 1 (1.3%) in the LESS group (p=0.172).
  
  
  CONCLUSIONS
  The LESS and robotic approaches both appear reasonable and each may have benefits and limitations depending upon the patient population. Further studies are needed to validate these preliminary conclusions.
authors.affiliation: Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Catholic University of the Sacred Heart, Rome, Italy.
authors.forename: Anna
authors.initials: A
authors.lastname: Fagotti
authors.forename: Maria Lucia
authors.initials: ML
authors.lastname: Gagliardi
authors.forename: Francesco
authors.initials: F
authors.lastname: Fanfani
authors.forename: Maria Giovanna
authors.initials: MG
authors.lastname: Salerno
authors.forename: Alfredo
authors.initials: A
authors.lastname: Ercoli
authors.forename: Marco
authors.initials: M
authors.lastname: D'Asta
authors.forename: Lucia
authors.initials: L
authors.lastname: Tortorella
authors.forename: Luigi Carlo
authors.initials: LC
authors.lastname: Turco
authors.forename: Pedro
authors.initials: P
authors.lastname: Escobar
authors.forename: Giovanni
authors.initials: G
authors.lastname: Scambia
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016889:Endometrial Neoplasms / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D007044:Hysterectomy / Q000379:methods*; D010535:Laparoscopy / Q000379:methods*; D008197:Lymph Node Excision; D008875:Middle Aged; D009367:Neoplasm Staging; D012189:Retrospective Studies; D012371:Robotics / Q000379:methods*; D016896:Treatment Outcome