title: Twelve-week aerobic training decreases chemerin level and improves cardiometabolic risk factors in overweight and obese men.
abstract: OBJECTIVE
  The inflammatory state of adipose tissue in obese subjects may be the most important factor linking increased adipose tissue mass to insulin resistance. Chemerin is a newly discovered adipokine that plays an important role in macrophage infiltration into adipose tissue and may contribute to the development of inflammation and insulin resistance. We examined the effects of 12 weeks of aerobic training on serum chemerin levels in association with cardiovascular risk factors in overweight and obese males.
  
  
  METHODS
  Twenty-one overweight and obese subjects [44.3 (±4.1 yrs, body mass index (BMI) ≥25 kg/m(2)) were assigned to exercise training (obese EX, n= 11) and control (obese CON, n= 10) groups. The obese EX group participated in 12 weeks of progressive aerobic training 5 days a week. Serum chemerin, insulin resistance, lipid profiles, blood pressure, and body composition were all measured before and after the training.
  
  
  RESULTS
  After the aerobic training, waist circumference (P=0.009), fat percent (P=0.03), visceral fat (P=0.03), subcutaneous fat (P=0.01), fasting glucose (P=0.01), insulin resistance (P=0.03), triglyceride (P=0.05), total cholesterol (P=0.04), low-density lipoprotein cholesterol (P=0.05) and systolic blood pressure (P=0.04) of participates were significantly decreased. Concurrently, serum chemerin concentrations were significantly decreased after aerobic program (P=0.02).
  
  
  CONCLUSIONS
  Aerobic training caused an improvement in cardiometabolic risk factors in obese subjects, and this improvement was accompanied by decreased chemerin levels.
authors.affiliation: Department of Sport Sciences, Arak University, Arak, IR Iran.
authors.forename: Abbas
authors.initials: A
authors.lastname: Saremi
authors.forename: Nader
authors.initials: N
authors.lastname: Shavandi
authors.forename: Mohammad
authors.initials: M
authors.lastname: Parastesh
authors.forename: Hassan
authors.initials: H
authors.lastname: Daneshmand