title: Bioactive compounds from marine sponges and their symbiotic microbes: a potential source of nutraceuticals.
abstract: Sponges are considered as the chemical factory in marine environment because of its immense production of chemically diverse compounds. Other than the chemical diversity, these compounds possess remarkable bioactivities. This great potential has aroused applications of sponge-derived compounds as therapeutics and at present, a number of promising compounds are in clinical and preclinical trials. Recently, nutraceuticals have received considerable interest among the health conscious community because of its multiple therapeutic effects. Natural health-promoting substances gain continuous popularity as nutraceuticals due to its reduced risk of side effects. This overview discusses the potentials of marine sponge-derived bioactivities as natural health-promoting compounds.
authors.affiliation: Department of Chemistry, Pukyong National University, Busan, Republic of Korea. sknkim@pknu.ac.kr
authors.forename: Se-Kwon
authors.initials: SK
authors.lastname: Kim
authors.forename: Pradeep
authors.initials: P
authors.lastname: Dewapriya
mesh_terms: D039903:Actinobacteria / Q000254:growth & development / Q000378:metabolism; D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000378:metabolism / Q000627:therapeutic use; D000924:Anticholesteremic Agents / Q000378:metabolism / Q000627:therapeutic use; D000975:Antioxidants / Q000378:metabolism / Q000627:therapeutic use; D059001:Aquatic Organisms / Q000254:growth & development / Q000378:metabolism*; D003094:Collagen / Q000378:metabolism / Q000627:therapeutic use; D000458:Cyanobacteria / Q000254:growth & development / Q000378:metabolism; D019587:Dietary Supplements / Q000032:analysis; D005658:Fungi / Q000254:growth & development / Q000378:metabolism; D006293:Health Promotion; D006801:Humans; D010860:Pigments, Biological / Q000737:chemistry / Q000302:isolation & purification / Q000378:metabolism / Q000627:therapeutic use; D011161:Porifera / Q000254:growth & development / Q000378:metabolism* / Q000382:microbiology*; D013559:Symbiosis
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D000924:Anticholesteremic Agents; D000975:Antioxidants; D010860:Pigments, Biological; D003094:Collagen