title: [Adaptive response of blood lymphocytes as a marker of hemopoiesis status in exposed persons].
abstract: An obvious correlation between the type of reaction manifested by peripheral blood lymphocytes to low dose irradiation in vitro (adaptive potential), the RBM cell composition (during the period of the major exposure), and the peripheral blood cell composition (at a late time period coincident with the studies of induced radioresistance) has been found in the Techa riverside residents in the later periods after the onset of a long-term low-dose rate radiation exposure (55-60 years later) within a range of individual red bone marrow doses from 0.01 to 1.79 Gy. The nature of these dependences observed in chronically exposed individuals differs from that revealed in the controls. It can be suggested based on the results of the study that the capacity for the adaptive response shown by peripheral blood lymphocytes donated by exposed persons in the remote period after exposure can be regarded as a biological marker of the functional state of the hemopoietic stem cell pool.
authors.forename: A V
authors.initials: AV
authors.lastname: Akleev
authors.forename: A V
authors.initials: AV
authors.lastname: Aleshchenko
authors.forename: O V
authors.initials: OV
authors.lastname: Kudriashova
authors.forename: L P
authors.initials: LP
authors.lastname: Semenova
authors.forename: A M
authors.initials: AM
authors.lastname: Serebrianyĭ
authors.forename: O I
authors.initials: OI
authors.lastname: Khudiakova
authors.forename: I I
authors.initials: II
authors.lastname: Pelevina
mesh_terms: D000222:Adaptation, Physiological; D000328:Adult; D000368:Aged; D001854:Bone Marrow Cells / Q000528:radiation effects; D004307:Dose-Response Relationship, Radiation; D005260:Female; D006410:Hematopoiesis / Q000528:radiation effects*; D006412:Hematopoietic Stem Cells / Q000528:radiation effects; D006801:Humans; D007220:Industrial Waste / Q000009:adverse effects; D018655:Lymphocyte Count; D008214:Lymphocytes / Q000166:cytology / Q000502:physiology* / Q000528:radiation effects*; D008297:Male; D008875:Middle Aged; D011839:Radiation, Ionizing; D045483:Rivers; D012426:Russia; D013326:Strontium Radioisotopes / Q000009:adverse effects; D014878:Water Pollution, Radioactive / Q000009:adverse effects*
chemical_list: D007220:Industrial Waste; D013326:Strontium Radioisotopes