title: Outcomes of ileocolic resection and right hemicolectomies for Crohn's patients in comparison with non-Crohn's patients and the impact of perioperative immunosuppressive therapy with biologics and steroids on inpatient complications.
abstract: BACKGROUND
  The purpose of this study was to compare medication use and complication rates between Crohn's disease (CD) and non-CD patients undergoing ileocolic resections and right hemicolectomies.
  
  
  METHODS
  A review of patients who underwent ileocolic resections and right hemicolectomies from January 1, 2003, through December 31, 2010, was performed. Data collected included demographics and clinical information, biologics use (eg, infliximab, adalimumab), other medication use (eg, steroids), complications, and mortality.
  
  
  RESULTS
  There were 791 records reviewed, with 93 CD patients. There was no significant difference in major or minor complications, anastomotic leaks, operating room time, or postoperative ileus occurrence between the CD and non-CD groups (P > .05). Use of biologics and steroids were significantly higher among the CD patients. Mortality, age, and American Society of Anesthesiologists score were significantly higher in the non-CD group.
  
  
  CONCLUSIONS
  Ileocolic resections and right hemicolectomies in CD patients are not associated with an increase in complication rates even when the patients use steroids and biologics in the preoperative period.
authors.affiliation: Grand Rapids Medical Education Partners/Michigan State University, Grand Rapids, MI 49546, USA.
authors.forename: Christopher
authors.initials: C
authors.lastname: Mascarenhas
authors.forename: Robert
authors.initials: R
authors.lastname: Nunoo
authors.forename: Theodor
authors.initials: T
authors.lastname: Asgeirsson
authors.forename: Rachelle
authors.initials: R
authors.lastname: Rivera
authors.forename: Don
authors.initials: D
authors.lastname: Kim
authors.forename: Rebecca
authors.initials: R
authors.lastname: Hoedema
authors.forename: Nadav
authors.initials: N
authors.lastname: Dujovny
authors.forename: Martin
authors.initials: M
authors.lastname: Luchtefeld
authors.forename: Alan T
authors.initials: AT
authors.lastname: Davis
authors.forename: Ryan
authors.initials: R
authors.lastname: Figg
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003082:Colectomy; D003424:Crohn Disease / Q000188:drug therapy / Q000401:mortality / Q000601:surgery*; D005260:Female; D006801:Humans; D007082:Ileum / Q000601:surgery*; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D007410:Intestinal Diseases / Q000601:surgery; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000453:epidemiology*; D012189:Retrospective Studies; D016896:Treatment Outcome
chemical_list: D007166:Immunosuppressive Agents