title: A gene-based approach for testing association of rare alleles.
abstract: Rare genetic variants have been shown to be important to the susceptibility of common human diseases. Methods for detecting association of rare genetic variants are drawing much attention. In this report, we applied a gene-based approach to the 200 simulated data sets of unrelated individuals. The test can detect the association of some genes with multiple rare variants.
authors.affiliation: Department of Biostatistics, Georgia Health Sciences University, 1120 15th Street, Augusta, GA 30912, USA. hxu@georgiahealth.edu.
authors.forename: Hongyan
authors.initials: H
authors.lastname: Xu
authors.forename: Varghese
authors.initials: V
authors.lastname: George