title: [The systemic inflammatory response syndrome correction in acute destructive pancreatitis].
abstract: Acute pancreatitis is a disease of variable severity. In which some patients experience mild, self-limited attacks while others manifest a severe, highly morbid, and frequently lethal attack. The exact mechanisms by which diverse etiological factors induce an attack are still unclear. Recent studies have established the role played by inflammatory mediators in the pathogenesis of acute pancreatitis. In our research we have estimated influence of not steroid anti-inflammatory preparation on synthesis pro-and anti-inflammatory Cytokines at healthy donors and at patients with Acute pancreatitis.
authors.forename: M A
authors.initials: MA
authors.lastname: Agapov
authors.forename: M V
authors.initials: MV
authors.lastname: Khoreva
authors.forename: V A
authors.initials: VA
authors.lastname: Gorskiĭ
mesh_terms: D000328:Adult; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000627:therapeutic use*; D018929:Cell Culture Techniques; D002478:Cells, Cultured; D016207:Cytokines / Q000097:blood / Q000276:immunology; D004305:Dose-Response Relationship, Drug; D004359:Drug Therapy, Combination; D006801:Humans; D007275:Injections, Intravenous; D007963:Leukocytes, Mononuclear / Q000187:drug effects / Q000276:immunology; D008024:Ligands; D019283:Pancreatitis, Acute Necrotizing / Q000097:blood / Q000150:complications / Q000188:drug therapy* / Q000276:immunology; D010894:Piroxicam / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D018746:Systemic Inflammatory Response Syndrome / Q000097:blood / Q000209:etiology / Q000276:immunology / Q000517:prevention & control*; D051194:Toll-Like Receptor 1 / Q000276:immunology; D051195:Toll-Like Receptor 2 / Q000276:immunology; D051197:Toll-Like Receptor 4 / Q000276:immunology; D055815:Young Adult
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D016207:Cytokines; D008024:Ligands; C495342:TLR2 protein, human; C495345:TLR4 protein, human; D051194:Toll-Like Receptor 1; D051195:Toll-Like Receptor 2; D051197:Toll-Like Receptor 4; D010894:Piroxicam; C059451:lornoxicam