title: Temperature-modulated fluorescence tomography in a turbid media.
abstract: High scattering in biological tissues makes fluorescence tomography inverse problem very challenging in thick medium. We describe an approach termed "temperature-modulated fluorescence tomography" that can acquire fluorescence images at focused ultrasound resolution. By utilizing recently emerged temperature sensitive fluorescence contrast agents, this technique provides fluorescence images with high resolution prior to any reconstruction process. We demonstrate that this technique is well suited to resolve small fluorescence targets located several centimeters deep in tissue.
authors.forename: Yuting
authors.initials: Y
authors.lastname: Lin
authors.forename: Linden
authors.initials: L
authors.lastname: Bolisay
authors.forename: Michael
authors.initials: M
authors.lastname: Ghijsen
authors.forename: Tiffany C
authors.initials: TC
authors.lastname: Kwong
authors.forename: Gultekin
authors.initials: G
authors.lastname: Gulsen