title: The frequency and magnitude of growth failure in a group of HIV-infected children in Cameroon.
abstract: BACKGROUND
  Growth impairment is a major manifestation of HIV infection in children and has been implicated as a major contributor to both morbidity and mortality. This study the first to be done in this setting, was aimed at comparing the growth of HIV infected children to that of non-infected children in two referral health facilities in Yaoundé, Cameroon.
  
  
  METHODS
  A prospective case control study was carried out on 39 HIV infected children in two referral hospitals and followed up for a period of 12 months. Anthropometric measurements were taken and the sociodemographic variables of mothers and infants noted. Thirty nine infected children (mean age 45.3 months ± 41.6 SD) were age and sex matched with 39 non-infected children (mean age 44.4 ± 40.7 months).
  
  
  RESULTS
  Out of the 39 infected children, 26 (66.7%) had at least one of the three anthropometric indices (weight for height, weight for age, height for age) Z scores less than -2. Throughout follow-up, 20.5% of the infected children were wasted (weight to height Z score < -2) versus none in the control group, 56.4% underweight (weight for age Z score < -2) in the infected versus 2.6% in the control group, and 51.3% stunted (height for age Z score < -2) in contrast to 5.1% in the control group.
  
  
  CONCLUSIONS
  This study demonstrated that wasting; underweight and stunting are common findings in HIV- infected children, thus stressing the importance of anthropometry in the routine care of these children.
authors.affiliation: Yaoundé Gynaeco-Obstetric and Pediatric Hospital/Faculty of Medicine and Biomedical Sciences, University of Yaoundé I, Cameroon.
authors.forename: Andreas
authors.initials: A
authors.lastname: Chiabi
authors.forename: Jacqueline
authors.initials: J
authors.lastname: Lebela
authors.forename: Marie
authors.initials: M
authors.lastname: Kobela
authors.forename: Lawrence
authors.initials: L
authors.lastname: Mbuagbaw
authors.forename: Marie Thérèse
authors.initials: MT
authors.lastname: Obama
authors.forename: Tetanye
authors.initials: T
authors.lastname: Ekoe
mesh_terms: D000293:Adolescent; D000886:Anthropometry; D002163:Cameroon / Q000453:epidemiology; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006130:Growth Disorders / Q000453:epidemiology / Q000209:etiology*; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D007223:Infant; D008297:Male; D011446:Prospective Studies; D013851:Thinness / Q000453:epidemiology / Q000209:etiology*; D019282:Wasting Syndrome / Q000453:epidemiology / Q000209:etiology