title: Wavelet analysis demonstrates no abnormality in contralateral suppression of otoacoustic emissions in tinnitus patients.
abstract: The efferent auditory system is thought to play a role in the origin of tinnitus. Part of this system can be tested in humans with contralateral suppression of otoacoustic emissions. Stimulation of the medial olivocochlear efferent system is responsible for this reduction of otoacoustic emissions after contralateral acoustic stimulation. Previous research on patients with tinnitus showed inconclusive results. With wavelet analysis both time and frequency information of the emission can be analysed and compared. Contralateral suppression of otoacoustic emissions was therefore measured in tinnitus patients (n = 26) and normal subjects (n = 37) and analysed using wavelets. No significant difference in suppression was found between the tinnitus patients and the control group.
authors.affiliation: Department of Otorhinolaryngology/Head and Neck Surgery, University Medical Center Groningen, P.O. Box 30.001, 9700 RB Groningen, The Netherlands. l.i.geven@umcg.nl
authors.forename: Leontien I
authors.initials: LI
authors.lastname: Geven
authors.forename: Hero P
authors.initials: HP
authors.lastname: Wit
authors.forename: Emile
authors.initials: E
authors.lastname: de Kleine
authors.forename: Pim
authors.initials: P
authors.lastname: van Dijk
mesh_terms: D000161:Acoustic Stimulation / Q000379:methods*; D000328:Adult; D016022:Case-Control Studies; D003051:Cochlea / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015233:Models, Statistical; D016011:Normal Distribution; D017084:Otoacoustic Emissions, Spontaneous / Q000502:physiology*; D012022:Reflex, Acoustic; D015203:Reproducibility of Results; D059629:Signal-To-Noise Ratio; D013997:Time Factors; D014012:Tinnitus / Q000503:physiopathology*; D058067:Wavelet Analysis