title: [Molecular investigation of enteroaggregative, shiga toxin-producing E. coli O104:H4 isolated in Poland during the recent international outbreak--characteristic of epidemic clone].
abstract: Since early May 2011 a large food-borne outbreak caused by E. coli O104:H4 affected Germany then spread over 13 European countries, U.S.A. and Canada. The outbreak strain was found to possess an unusual combination of enteroaggregative E. coli pathotype with StxII. In this report we described the molecular investigation of epidemic clone in Poland during the international outbreak. We confirmed three cases of E. coli O104:H4 infections. The molecular characteristics of the Polish E. coli O104:H4 isolates including virulence profile, antimicrobial resistance, PFGE and plasmids profiles were corresponded with Germany outbreak strains.
authors.affiliation: Zakład Bakteriologii Narodowego Instytutu Zdrowia Publicznego-Państwowego Zakładu Higieny w Warszawie. jszych@pzh.gov.pl
authors.forename: Aleksandra
authors.initials: A
authors.lastname: Januszkiewicz
authors.forename: Anna
authors.initials: A
authors.lastname: Chróst
authors.forename: Tomasz
authors.initials: T
authors.lastname: Wołkowicz
authors.forename: Grzegorz
authors.initials: G
authors.lastname: Madajczak
authors.forename: Monika
authors.initials: M
authors.lastname: Wasiak
authors.forename: Jolanta
authors.initials: J
authors.lastname: Szych
mesh_terms: D002170:Canada / Q000453:epidemiology; D004196:Disease Outbreaks; D004927:Escherichia coli Infections / Q000453:epidemiology* / Q000235:genetics*; D005060:Europe / Q000453:epidemiology; D005517:Foodborne Diseases / Q000453:epidemiology* / Q000235:genetics*; D016680:Genome, Bacterial; D005858:Germany / Q000453:epidemiology; D006801:Humans; D011044:Poland; D017422:Sequence Analysis, DNA; D054323:Shiga-Toxigenic Escherichia coli / Q000145:classification / Q000235:genetics* / Q000472:pathogenicity; D013045:Species Specificity; D014774:Virulence / Q000235:genetics