title: Does maternal depression predict developmental outcome in 18 month old infants?
abstract: OBJECTIVE
  Our aim was to examine the associations between maternal depression in the first 6 months postpartum, home environment and cognitive, language and motor development in infants at 18 months of age.
  
  
  METHODS
  This article reports results from the control group (n=312 full term; n=48 preterm) of the prospective Docosahexaenoic acid (DHA) to Optimise Maternal Infant Outcome (DOMInO) Randomised Controlled Trial. Mothers in South Australia completed the Edinburgh Postnatal Depression Scale (EPDS) at 6 weeks and 6 months postpartum. Infant development was assessed when children were 18 months old with the Bayley Scales of Infant and Toddler Development Version III and mothers completed the Home Screening Questionnaire at this assessment.
  
  
  RESULTS
  There were no significant associations between maternal depression in the first 6 months postpartum and cognitive, language or motor development after controlling for infant prematurity, breastfeeding status and socio-economic level. Home environment remained a significant predictor of development after controlling for potential confounding variables. Using mediation models, we did not find an association between maternal depression and developmental outcome through home environment.
  
  
  CONCLUSIONS
  Maternal depression in the first 6 months postpartum was not associated with infant development at 18 months of age. Further studies should focus on women with chronic depression.
authors.affiliation: Child Nutrition Research Centre, Women's and Children's Hospital, Flinders Medical Centre, and Women's and Children's Health Research Institute, 72 King William Road, Adelaide, SA 5006, Australia.
authors.forename: Alicia M
authors.initials: AM
authors.lastname: Piteo
authors.forename: Lisa N
authors.initials: LN
authors.lastname: Yelland
authors.forename: Maria
authors.initials: M
authors.lastname: Makrides
mesh_terms: D003071:Cognition; D019052:Depression, Postpartum / Q000453:epidemiology*; D002658:Developmental Disabilities / Q000453:epidemiology*; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007234:Infant, Premature; D007804:Language Development; D008297:Male; D009048:Motor Skills