title: New spirostanol glycosides from Solanum nigrum and S. jasminoides.
abstract: A new characteristic steroidal glycoside possessing a hydroxyl group at C-23, inunigroside A (1), was isolated from the withered berries of Solanum nigrum L. On the basis of spectroscopic analysis, the structure of 1 was characterized as (5α,22S,23S,25R)-3β,23-dihydroxyspirostane 3-O-β-lycotetraoside. Next, a major steroidal sapogenol, (22R, 25S)-3β,15α-dihydroxy-spirost-5-ene (3), was obtained from the acid hydrolysate of the methanolic extract of the aerial parts of Solanum jasminoides L. A new bisdesmoside, 3-O-β-D-glucopyranosyl-(1→4)-β-D-glucopyranosyl-(1→4)-β-D-glucopyranosyl (22R,25S)-3β,15α-dihydroxyspirost-5-ene 15-O-α-L-rhamnopyranoside (4), named jasminoside A, was isolated from the methanolic extract of S. jasminoides.
authors.affiliation: Faculty of Pharmaceutical Sciences, Sojo University, 4-22-1 Ikeda, Kumamoto, 860-0082, Japan.
authors.forename: Mizuho
authors.initials: M
authors.lastname: Ohno
authors.forename: Kotaro
authors.initials: K
authors.lastname: Murakami
authors.forename: Mona
authors.initials: M
authors.lastname: El-Aasr
authors.forename: Jian-Rong
authors.initials: JR
authors.lastname: Zhou
authors.forename: Kazumi
authors.initials: K
authors.lastname: Yokomizo
authors.forename: Masateru
authors.initials: M
authors.lastname: Ono
authors.forename: Toshihiro
authors.initials: T
authors.lastname: Nohara
mesh_terms: D006027:Glycosides / Q000737:chemistry*; D015394:Molecular Structure; D032322:Solanum / Q000737:chemistry*; D032324:Solanum nigrum / Q000737:chemistry*; D013150:Spirostans / Q000737:chemistry*
chemical_list: D006027:Glycosides; D013150:Spirostans