title: Management of noncardiac chest pain in women.
abstract: Noncardiac chest pain (NCCP) is very prevalent in the community. Although mortality remains low, morbidity and the financial implications are high. Women, especially those of middle age, should be thoroughly investigated as per current guidelines for coronary artery disease before labeling their chest pain as NCCP. Gastroesophageal reflux disease is the most common cause of NCCP; however other esophageal pathology including esophageal hypersensitivity, neuromuscular disease and eosinophilic esophagitis may also cause NCCP. Proton pump inhibitors are commonly used initially to manage NCCP, although patients who do not respond to this therapy require further investigation and differing treatment regimes. This article will focus on current knowledge regarding GI tract-related NCCP management strategies.
authors.affiliation: Gosford Hospital, Division of Gastroenterology, New South Wales, Australia.
authors.forename: Raghubinder S
authors.initials: RS
authors.lastname: Gill
authors.forename: Jo S
authors.initials: JS
authors.lastname: Collins
authors.forename: Nicolas J
authors.initials: NJ
authors.lastname: Talley
mesh_terms: D002637:Chest Pain / Q000209:etiology*; D003324:Coronary Artery Disease / Q000150:complications / Q000175:diagnosis*; D003937:Diagnosis, Differential; D019468:Disease Management; D057765:Eosinophilic Esophagitis / Q000150:complications / Q000175:diagnosis; D004947:Esophagus / Q000473:pathology*; D005260:Female; D005764:Gastroesophageal Reflux / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D006801:Humans; D059408:Pain Management; D015995:Prevalence; D054328:Proton Pump Inhibitors / Q000627:therapeutic use
chemical_list: D054328:Proton Pump Inhibitors