title: Overdose of Vinblastine in place of Vinorelbine during IGEV chemotherapy.
abstract: Any class of drugs is susceptible to errors, in case of antineoplastic agents the medication errors may cause severe and life-threatening toxicity due to very limited therapeutic index with toxic events even at therapeutic dosage, to complexity of regimens and the particular vulnerable population. We report herein a case of Vinblastine (VBL) accidental overdose, the cause of mistake, the toxic effect and the salvage therapy adopted in a young lady suffering of Hodgkin relapse during IGEV chemotherapy.
authors.forename: S M L
authors.initials: SM
authors.lastname: Aversa
authors.forename: S
authors.initials: S
authors.lastname: Zanon
authors.forename: D
authors.initials: D
authors.lastname: Marino
authors.forename: F
authors.initials: F
authors.lastname: Canova
authors.forename: V
authors.initials: V
authors.lastname: Chiarion-Sileni
authors.forename: A
authors.initials: A
authors.lastname: Jirillo
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage*; D056486:Chemical and Drug Induced Liver Injury / Q000188:drug therapy; D003092:Colitis / Q000139:chemically induced / Q000188:drug therapy; D005260:Female; D006689:Hodgkin Disease / Q000188:drug therapy*; D006801:Humans; D019300:Medical Errors / Q000009:adverse effects*; D009503:Neutropenia / Q000139:chemically induced; D010146:Pain / Q000139:chemically induced / Q000188:drug therapy; D063487:Prescription Drug Misuse; D013921:Thrombocytopenia / Q000139:chemically induced; D014747:Vinblastine / Q000008:administration & dosage / Q000009:adverse effects* / Q000031:analogs & derivatives*; D000077235:Vinorelbine
chemical_list: D014747:Vinblastine; D000077235:Vinorelbine