title: Isolation of Kingella kingae in the oropharynx during K. kingae arthritis in children.
abstract: Kingella kingae arthritis in children is now mainly diagnosed by PCR, which has surpassed conventional culture of joint fluid. As oropharynx colonization is the first step of Kingella kingae invasion, we prospectively investigated the possibility of cultivating it from throat swabs, in children hospitalized for K. kingae arthritis. Throat culture was 5.6-fold more sensitive than joint fluid cultures in isolating K. kingae (66.7% vs. 11.9% respectively, p <0.001) and may be used to perform antibiotic susceptibility testing.
authors.affiliation: University Paris Diderot, Sorbonne Paris Cité AP-HP, Laboratoire de Microbiologie, Hôpital Robert-Debré AP-HP, 48 Boulevard Sérurier, Paris, France.
authors.forename: R
authors.initials: R
authors.lastname: Basmaci
authors.forename: B
authors.initials: B
authors.lastname: Ilharreborde
authors.forename: P
authors.initials: P
authors.lastname: Bidet
authors.forename: C
authors.initials: C
authors.lastname: Doit
authors.forename: M
authors.initials: M
authors.lastname: Lorrot
authors.forename: K
authors.initials: K
authors.lastname: Mazda
authors.forename: E
authors.initials: E
authors.lastname: Bingen
authors.forename: S
authors.initials: S
authors.lastname: Bonacorsi
mesh_terms: D001170:Arthritis, Infectious / Q000382:microbiology*; D001427:Bacterial Toxins / Q000235:genetics; D002675:Child, Preschool; D003470:Culture Media; D005260:Female; D006801:Humans; D007223:Infant; D017882:Kingella kingae / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D008297:Male; D016870:Neisseriaceae Infections / Q000382:microbiology*; D009960:Oropharynx / Q000382:microbiology*; D016133:Polymerase Chain Reaction / Q000379:methods; D013048:Specimen Handling / Q000379:methods*; D013582:Synovial Fluid / Q000382:microbiology
chemical_list: D001427:Bacterial Toxins; D003470:Culture Media