title: [Hemolytic disease of the newborn has not vanished from Finland--routine protection of RhD negative mothers during pregnancy is justifiable].
abstract: Prophylaxis of RhD negative mothers with anti-D immunoglobulin after childbirth is the most important procedure reducing the immunization of the mother and the risk of severe hemolytic disease of the newborn. In spite of this, anti-D antibodies having relevance to pregnancy are later detected in 1.8% of RhD negative mothers. Half of these cases could be prevented by routine anti-D prophylaxis given to the mothers during weeks 28 to 34 of pregnancy. Convincing evidence of the effectiveness of this measure has accumulated in the last few years, and application of the treatment is justified also in Finland.
authors.affiliation: Suomen Punainen Risti, Veripalvelu.
authors.forename: Susanna
authors.initials: S
authors.lastname: Sainio
authors.forename: Malla
authors.initials: M
authors.lastname: Kuosmanen
mesh_terms: D005260:Female; D005387:Finland / Q000453:epidemiology; D006801:Humans; D007155:Immunologic Factors / Q000276:immunology / Q000627:therapeutic use*; D007231:Infant, Newborn; D007518:Isoantibodies / Q000276:immunology / Q000627:therapeutic use; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000517:prevention & control*; D011292:Premedication; D011295:Prenatal Care; D012203:Rh Isoimmunization / Q000453:epidemiology / Q000517:prevention & control*; D018029:Rho(D) Immune Globulin / Q000276:immunology / Q000627:therapeutic use*
chemical_list: D007155:Immunologic Factors; D007518:Isoantibodies; D018029:Rho(D) Immune Globulin