title: Traumatic aortic injuries associated with major visceral vascular injuries in major blunt trauma patients.
abstract: BACKGROUND
  The objectives of this study were to report the clinical and radiological characteristics and outcomes of a series of acute traumatic aortic injuries (ATAIs) with associated injury to major aortic abdominal visceral branches (MAAVBs).
  
  
  METHODS
  From January 2000 to August 2011, 10 consecutive major blunt trauma patients with associated ATAI and injury to MAAVBs (group A) and 42 major blunt trauma patients presenting only an ATAI without MAAVB injuries (group B) were admitted to our institution.
  
  
  RESULTS
  Overall in-hospital mortality was 32.7%. In-hospital mortality in group A was 40% and in group B it was 31% (p = 0.86). Observed in-hospital mortality was slightly lower than the expected in-hospital mortality in both groups. Mean peak creatine phosphokinase was significantly higher in group A than in group B patients (23,008 ± 33,400 vs. 3,970 ± 3,495 IU/L; p < 0.001). Acute renal injury occurred in 50% of group A and in 26.2% of group B patients. Hemodiafiltration was required in 30% of group A and in 9.5% of group B patients. Median follow-up time was 64 months (range = 1-130 months). Group A survival was 60% at 1, 5 and 10 years. Group B survival was 69% at 1 year and 63.3% at 5 and 10 years (p = 0.15).
  
  
  CONCLUSIONS
  Aortic injuries associated with MAAVB injuries in major trauma patients seem to present in a different clinical scenario. These patients present increased risk of rhabdomyolysis, visceral ischemia, and acute renal failure, as well as higher in-hospital mortality. A multidisciplinary approach combining endovascular and open surgical techniques for a staged treatment of these life-threatening aortic and MAAVB injuries is mandatory in this critical subset of trauma patients.
authors.affiliation: Department of Cardiovascular Surgery, Complejo Hospitalario Universitario de A Coruña, As Xubias No. 84, 15006, A Coruña, Spain. Victor.X.Mosquera.Rodriguez@sergas.es
authors.forename: Victor X
authors.initials: VX
authors.lastname: Mosquera
authors.forename: Milagros
authors.initials: M
authors.lastname: Marini
authors.forename: Ignacio
authors.initials: I
authors.lastname: Cao
authors.forename: Daniel
authors.initials: D
authors.lastname: Gulías
authors.forename: Javier
authors.initials: J
authors.lastname: Muñiz
authors.forename: José M
authors.initials: JM
authors.lastname: Herrera-Noreña
authors.forename: José J
authors.initials: JJ
authors.lastname: Cuenca
mesh_terms: D000328:Adult; D000368:Aged; D001011:Aorta / Q000293:injuries*; D005260:Female; D017052:Hospital Mortality; D006801:Humans; D007022:Hypotension / Q000209:etiology; D053208:Kaplan-Meier Estimate; D008297:Male; D008875:Middle Aged; D061330:Multidetector Computed Tomography; D057772:Vascular System Injuries / Q000150:complications* / Q000000981:diagnostic imaging / Q000401:mortality; D014781:Viscera / Q000098:blood supply*; D014949:Wounds, Nonpenetrating / Q000150:complications* / Q000000981:diagnostic imaging / Q000401:mortality