title: The critical review of methodologies and approaches to assess the inherent skin sensitization potential (skin allergies) of chemicals. Part I.
abstract: To critically review currently available methods, or methods under development (in vivo, in vitro, in silico, etc.) used in the evaluation of skin sensitization potential and their applicability in the derivation of quantitative 'safety thresholds'.
authors.affiliation: National Allergy Research Centre, Department of Dermato-Allergology, Copenhagen University Hospital Gentofte, Niels Andersensvej 65, DK-2900 Hellerup, Denmark.
authors.forename: Jacob P
authors.initials: JP
authors.lastname: Thyssen
authors.forename: Elena
authors.initials: E
authors.lastname: Giménez-Arnau
authors.forename: Jean-Pierre
authors.initials: JP
authors.lastname: Lepoittevin
authors.forename: Torkil
authors.initials: T
authors.lastname: Menné
authors.forename: Anders
authors.initials: A
authors.lastname: Boman
authors.forename: Axel
authors.initials: A
authors.lastname: Schnuch
mesh_terms: D000485:Allergens / Q000633:toxicity*; D000818:Animals; D003257:Consumer Product Safety; D017449:Dermatitis, Allergic Contact / Q000209:etiology* / Q000517:prevention & control; D009783:Dermatitis, Occupational / Q000209:etiology / Q000517:prevention & control; D005060:Europe; D006801:Humans; D012882:Skin Tests / Q000379:methods*
chemical_list: D000485:Allergens