title: The effect of low level laser on condylar growth during mandibular advancement in rabbits.
abstract: BACKGROUND
  It has been shown that Low Level Laser (LLL) has a positive effect on bone formation. The aim of this study was to evaluate the effect of low level laser on condylar growth during mandibular advancement in rabbits.
  
  
  METHODS
  Continuous forward mandibular advancement was performed in fourteen male Albino rabbits with the mean age of 8 weeks and the mean weight of 1.5 ± 0.5 kg, with acrylic inclined planes. The rabbits were randomly assigned into two groups after 4 weeks. LLL (KLO3: wave length 630 nm) was irradiated at 3 points around the TMJ, through the skin in the first group. The exposure was performed for 3 minutes at each point (a total of 9 minutes) once a day for 3 weeks. The control group was not exposed to any irradiation. The rabbits in both groups were sacrificed after two months and the histological evaluation of TMJ was performed to compare fibrous tissue, cartilage, and new bone formation in condylar region in both groups. Disc displacement was also detected in both groups. Student's t-test, Exact Fisher and Chi square tests were used for the statistical analysis.
  
  
  RESULTS
  The formation of fibrous tissue was significantly lower, while bone formation was significantly greater in lased group as compared with control group. The thickness of cartilage did not differ significantly between two groups.
  
  
  CONCLUSIONS
  Irradiation of LLL (KLO3) during mandibular advancement in rabbits, increases bone formation in condylar region, while neither increase in the cartilage thickness nor fibrous tissues was observed.
authors.affiliation: Orthodontic Dept, Islamic Azad University, Tehran, Iran.
authors.forename: Mostafa
authors.initials: M
authors.lastname: Abtahi
authors.forename: Maryam
authors.initials: M
authors.lastname: Poosti
authors.forename: Nasrollah
authors.initials: N
authors.lastname: Saghravanian
authors.forename: Kamran
authors.initials: K
authors.lastname: Sadeghi
authors.forename: Hooman
authors.initials: H
authors.lastname: Shafaee
mesh_terms: D000818:Animals; D007834:Lasers; D028022:Low-Level Light Therapy; D008297:Male; D019186:Mandibular Advancement; D008335:Mandibular Condyle / Q000254:growth & development* / Q000528:radiation effects*; D011817:Rabbits