title: [Cardiovascular risks of corticosteroids].
abstract: Prolonged use of glucocorticoids is associated with an increase in cardiovascular morbidity and mortality: hypertension and atheroma mainly. Severe cardiovascular complications of pulse corticosteroids are related to underlying comobidities and require some precautions. There are probably individual factors of complications associated with polymorphisms of the glucocorticoid receptor. Without clearly established recommendations concerning prevention of cardiovascular risk, screening and treatment of risk factors during treatment is the best prevention possible. Screening and treatment of cardiovascular complications require a just prescription and appropriate surveillance.
authors.affiliation: Université Paris-Descartes, Hôtel-Dieu, service de médecine interne et thérapeutique, 75004 Paris, France. tali-anne.szwebel@htd.aphp.fr
authors.forename: Tali-Anne
authors.initials: TA
authors.lastname: Szwebel
authors.forename: Claire
authors.initials: C
authors.lastname: Le Jeunne
mesh_terms: D000305:Adrenal Cortex Hormones / Q000009:adverse effects* / Q000627:therapeutic use; D000893:Anti-Inflammatory Agents / Q000009:adverse effects* / Q000627:therapeutic use; D002318:Cardiovascular Diseases / Q000139:chemically induced* / Q000401:mortality / Q000517:prevention & control; D004334:Drug Administration Schedule; D006801:Humans; D006973:Hypertension / Q000139:chemically induced / Q000401:mortality / Q000517:prevention & control; D007166:Immunosuppressive Agents / Q000009:adverse effects* / Q000627:therapeutic use; D008134:Long-Term Care; D058226:Plaque, Atherosclerotic / Q000139:chemically induced / Q000401:mortality / Q000517:prevention & control; D020551:Pulse Therapy, Drug; D012307:Risk Factors
chemical_list: D000305:Adrenal Cortex Hormones; D000893:Anti-Inflammatory Agents; D007166:Immunosuppressive Agents