title: HECT and RING finger families of E3 ubiquitin ligases at a glance.
authors.affiliation: Laboratory of Protein Dynamics and Signaling, Center for Cancer Research, National Cancer Institute-Frederick, 1050 Boyles Street, Frederick, MD 21702,  USA.
authors.forename: Meredith B
authors.initials: MB
authors.lastname: Metzger
authors.forename: Ventzislava A
authors.initials: VA
authors.lastname: Hristova
authors.forename: Allan M
authors.initials: AM
authors.lastname: Weissman
mesh_terms: D000818:Animals; D017209:Apoptosis; D059447:Cell Cycle Checkpoints; D006801:Humans; D008954:Models, Biological; D008958:Models, Molecular; D018919:Neovascularization, Physiologic; D046988:Proteasome Endopeptidase Complex / Q000378:metabolism; D017434:Protein Structure, Tertiary; D051736:Proto-Oncogene Proteins c-mdm2 / Q000378:metabolism; D054829:RING Finger Domains; D016159:Tumor Suppressor Protein p53 / Q000378:metabolism; D044767:Ubiquitin-Protein Ligases / Q000737:chemistry / Q000145:classification / Q000378:metabolism*; D054875:Ubiquitination
chemical_list: D016159:Tumor Suppressor Protein p53; D051736:Proto-Oncogene Proteins c-mdm2; D044767:Ubiquitin-Protein Ligases; D046988:Proteasome Endopeptidase Complex