title: Genomic position mapping discrepancies of commercial SNP chips.
abstract: The field of genetics has come to rely heavily on commercial genotyping arrays and accompanying annotations for insights into genotype-phenotype associations. However, in order to avoid errors and false leads, it is imperative that the annotation of SNP chromosomal positions is accurate and unambiguous. We report on genomic positional discrepancies of various SNP chips for human, cattle and mouse species, and discuss their causes and consequences.
authors.affiliation: Department of Clinical Sciences Malmö, CRC, Lund University, Malmö, Sweden.
authors.forename: João
authors.initials: J
authors.lastname: Fadista
authors.forename: Christian
authors.initials: C
authors.lastname: Bendixen
mesh_terms: D000818:Animals; D001483:Base Sequence; D002417:Cattle; D002874:Chromosome Mapping / Q000379:methods*; D033481:Chromosomes, Mammalian / Q000235:genetics; D016678:Genome / Q000235:genetics*; D055106:Genome-Wide Association Study; D023281:Genomics / Q000379:methods*; D060005:Genotyping Techniques; D006801:Humans; D051379:Mice; D008969:Molecular Sequence Data; D020411:Oligonucleotide Array Sequence Analysis / Q000379:methods*; D020641:Polymorphism, Single Nucleotide / Q000235:genetics*