title: Rapidly progressive primary leptomeningeal atypical teratoid/rhabdoid tumor: a report of 2 cases.
abstract: Atypical teratoid/rhabdoid tumor is a rare, highly malignant central nervous system tumor most commonly occurring in very young children. Atypical teratoid/rhabdoid tumor most often presents as an expanding mass with symptoms consistent with the location of the tumor and may present with metastatic leptomeningeal disease. The authors describe 2 cases of rapidly progressive, diffuse leptomeningeal atypical teratoid/rhabdoid tumor without a solid primary mass. These cases demonstrate a clinical picture that can easily be confused with a basilar meningitis, encephalomyelitis, or vasculitis.
authors.affiliation: Division of Pediatric Hematology/Oncology, St Louis University School of Medicine/Cardinal Glennon Children's Hospital, Bob Costas Cancer Center, St Louis, MO 63104, USA. kgauvain@slu.edu
authors.forename: Karen M
authors.initials: KM
authors.lastname: Gauvain
authors.forename: Benjamin H
authors.initials: BH
authors.lastname: Durham
authors.forename: Michele
authors.initials: M
authors.lastname: McHugh
authors.forename: Thomas J
authors.initials: TJ
authors.lastname: Geller
mesh_terms: D001932:Brain Neoplasms / Q000503:physiopathology*; D002675:Child, Preschool; D018450:Disease Progression; D005682:Gadolinium; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D008297:Male; D018335:Rhabdoid Tumor / Q000503:physiopathology*; D013724:Teratoma / Q000503:physiopathology*
chemical_list: D005682:Gadolinium