title: [Effect of compatibilities and proportions of shuanglong formula on acute myocardial infarction in rats].
abstract: OBJECTIVE
  To verify the rational of Chinese medicine Shuanglong formula.
  
  
  METHODS
  Rat models of acute myocardial ischemia were induced by hydrochloride isoproterenol. ECG J point change, myocardial infarction area and cellular enzyme (CK, LDH, SOD and MDA) levels were observed and detected to show protective effect of treatment groups.
  
  
  RESULTS
  The single drug prescriptions and compatibilities both could improve ECG performance, decrease levels of CK, LDH, SOD and MDA in serum, and reduce a certain myocardial infarct size.
  
  
  CONCLUSIONS
  The Shuanglong formula at the high dose of 3:7 was proved to be more effective on myocardial ischemia.
authors.affiliation: School of Phamacy, East China University of Science and Technology, Shanghai 200237, China.
authors.forename: Xiaoping
authors.initials: X
authors.lastname: Liang
authors.forename: Xi
authors.initials: X
authors.lastname: Chen
authors.forename: Yiming
authors.initials: Y
authors.lastname: Wang
authors.forename: Qionglin
authors.initials: Q
authors.lastname: Liang
authors.forename: Jun
authors.initials: J
authors.lastname: Wu
authors.forename: Guoan
authors.initials: G
authors.lastname: Luo
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage*; D004562:Electrocardiography / Q000187:drug effects; D007545:Isoproterenol; D008297:Male; D009203:Myocardial Infarction / Q000188:drug therapy*; D051381:Rats; D017207:Rats, Sprague-Dawley
chemical_list: D004365:Drugs, Chinese Herbal; C550108:shuanglong; D007545:Isoproterenol