title: [Prognostic factors of renal cell carcinoma].
abstract: The crucial predictor of renal cell carcinoma (RCC) is a clinical stage, although the significance of this parameter isn 't confirmed for all histological types of carcinomas. It remains unknown what factors ensure the sensitivity of the tumor to chemotherapy and why metastasis is accompanied by the development of resistance to therapy. The data about the prognosis of RCC rare variants are extremely scarce. Ubiquitin-dependent proteolysis plays an important role in the development of RCC, but the prognostic significance of this signal way's proteins is poorly understood. In order to find out significant factors for prognosis of RCC clinical course it's necessary to use the complex spectrum of tumor growth regulation factors and genetic tests.
authors.forename: L V
authors.initials: LV
authors.lastname: Moskvina
authors.forename: Iu Iu
authors.initials: IuIu
authors.lastname: Andreeva
authors.forename: P G
authors.initials: PG
authors.lastname: Mal'kov
mesh_terms: D002292:Carcinoma, Renal Cell / Q000235:genetics / Q000378:metabolism / Q000473:pathology / Q000628:therapy; D006801:Humans; D007680:Kidney Neoplasms / Q000235:genetics / Q000378:metabolism / Q000473:pathology / Q000628:therapy; D011379:Prognosis; D054875:Ubiquitination