title: Genetic requirement for ADAM10 in severe Staphylococcus aureus skin infection.
authors.forename: Naoko
authors.initials: N
authors.lastname: Inoshima
authors.forename: Yang
authors.initials: Y
authors.lastname: Wang
authors.forename: Juliane
authors.initials: J
authors.lastname: Bubeck Wardenburg
mesh_terms: D051722:ADAM Proteins / Q000037:antagonists & inhibitors / Q000235:genetics*; D000072197:ADAM10 Protein; D053829:Amyloid Precursor Protein Secretases / Q000037:antagonists & inhibitors / Q000235:genetics*; D000818:Animals; D001427:Bacterial Toxins / Q000378:metabolism; D015820:Cadherins / Q000378:metabolism; D002478:Cells, Cultured; D004151:Dipeptides / Q000494:pharmacology; D006460:Hemolysin Proteins / Q000378:metabolism; D006877:Hydroxamic Acids / Q000494:pharmacology; D015603:Keratinocytes / Q000378:metabolism; D008565:Membrane Proteins / Q000037:antagonists & inhibitors / Q000235:genetics*; D045726:Metalloproteases / Q000378:metabolism; D051379:Mice; D018345:Mice, Knockout; D009336:Necrosis / Q000378:metabolism; D012867:Skin / Q000187:drug effects / Q000473:pathology* / Q000503:physiopathology*; D013207:Staphylococcal Skin Infections / Q000235:genetics* / Q000378:metabolism / Q000473:pathology; D013211:Staphylococcus aureus / Q000378:metabolism / Q000472:pathogenicity*
chemical_list: C555398:3-(formylhydroxyamino)-2-(3-phenyl-1-propyl)butanoic acid (2,2-dimethyl-1-methylcarbamoyl-1-propyl)amide; D001427:Bacterial Toxins; D015820:Cadherins; D004151:Dipeptides; D006460:Hemolysin Proteins; D006877:Hydroxamic Acids; D008565:Membrane Proteins; C021091:staphylococcal alpha-toxin; D053829:Amyloid Precursor Protein Secretases; D045726:Metalloproteases; D051722:ADAM Proteins; D000072197:ADAM10 Protein; C491234:Adam10 protein, mouse