title: [Spontaneous neonatal arterial thrombosis: a report of 4 neonates].
abstract: Arterial thromboses are rare in newborns, mostly caused by arterial catheters. Neonatal arterial thrombosis occurring in other contexts is much rare. We report arterial thrombosis, not caused by catheterisation in 4 neonates hospitalised in the neonatology department of the Farhat Hached de Sousse hospital in Tunisia. The diagnosis of arterial thrombosis was made based on signs of ischemia in 2 patients affected by thrombosis of the iliac arteries. The symptoms were less clear: anuria associated with arterial high blood pressure in 1 patient affected by thrombosis of the abdominal aorta and by anuria with melena in a newborn with aortic and mesenteric thrombosis. Diagnosis was confirmed by Doppler sonography in 3 patients and based on autopsy data in 1 patient. A delay to consultation was noted in 3 patients, whose outcome was fatal. The progression was favourable after thrombolysis and anticoagulation using heparin in 1 patient with major aortic thrombosis. A review of the literature on the epidemiological, clinical, therapeutic and outcome data of the arterial thrombosis in the newborn child is provided.
authors.affiliation: Service de néonatologie, CHU Farhat Hached, Sousse, Tunisia. soniamerchaoui@yahoo.fr
authors.forename: S
authors.initials: S
authors.lastname: Nouri-Merchaoui
authors.forename: N
authors.initials: N
authors.lastname: Mahdhaoui
authors.forename: S
authors.initials: S
authors.lastname: Trabelsi
authors.forename: H
authors.initials: H
authors.lastname: Seboui
mesh_terms: D000792:Angiography; D000925:Anticoagulants / Q000627:therapeutic use; D001002:Anuria / Q000209:etiology*; D001012:Aorta, Abdominal; D001018:Aortic Diseases / Q000175:diagnosis* / Q000188:drug therapy; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D005260:Female; D006493:Heparin / Q000627:therapeutic use; D006801:Humans; D007083:Iliac Artery; D007231:Infant, Newborn; D007421:Intestine, Small / Q000098:blood supply; D007511:Ischemia / Q000188:drug therapy / Q000209:etiology*; D007668:Kidney / Q000098:blood supply; D007866:Leg / Q000098:blood supply; D008297:Male; D008551:Melena / Q000209:etiology*; D008638:Mesenteric Arteries; D008641:Mesenteric Vascular Occlusion / Q000175:diagnosis* / Q000188:drug therapy; D013300:Streptokinase / Q000627:therapeutic use; D015912:Thrombolytic Therapy; D013927:Thrombosis / Q000175:diagnosis* / Q000188:drug therapy; D014463:Ultrasonography; D018608:Ultrasonography, Doppler
chemical_list: D000925:Anticoagulants; D006493:Heparin; D013300:Streptokinase