title: Initial experience from a double-blind, placebo-controlled, clinical outcome study of ARC1779 in patients with thrombotic thrombocytopenic purpura.
authors.forename: Spero R
authors.initials: SR
authors.lastname: Cataland
authors.forename: Flora
authors.initials: F
authors.lastname: Peyvandi
authors.forename: Pier M
authors.initials: PM
authors.lastname: Mannucci
authors.forename: Bernhard
authors.initials: B
authors.lastname: Lämmle
authors.forename: Johanna A
authors.initials: JA
authors.lastname: Kremer Hovinga
authors.forename: Samuel J
authors.initials: SJ
authors.lastname: Machin
authors.forename: Marie
authors.initials: M
authors.lastname: Scully
authors.forename: Gail
authors.initials: G
authors.lastname: Rock
authors.forename: James C
authors.initials: JC
authors.lastname: Gilbert
authors.forename: Shangbin
authors.initials: S
authors.lastname: Yang
authors.forename: Haifeng
authors.initials: H
authors.lastname: Wu
authors.forename: Bernd
authors.initials: B
authors.lastname: Jilma
authors.forename: Paul
authors.initials: P
authors.lastname: Knoebl
mesh_terms: D051722:ADAM Proteins / Q000097:blood; D000071120:ADAMTS13 Protein; D000328:Adult; D052157:Aptamers, Nucleotide / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D055499:Catheter-Related Infections / Q000209:etiology; D003131:Combined Modality Therapy; D003244:Consciousness Disorders / Q000209:etiology; D004311:Double-Blind Method; D057239:Early Termination of Clinical Trials; D004827:Epilepsy / Q000209:etiology; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007262:Infusions, Intravenous / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D010951:Plasma Exchange; D010976:Platelet Count; D011485:Protein Binding / Q000187:drug effects; D017434:Protein Structure, Tertiary; D011697:Purpura, Thrombotic Thrombocytopenic / Q000150:complications / Q000188:drug therapy* / Q000503:physiopathology / Q000628:therapy; D014841:von Willebrand Factor / Q000037:antagonists & inhibitors* / Q000502:physiology
chemical_list: C526287:ARC 1779; D052157:Aptamers, Nucleotide; D007166:Immunosuppressive Agents; D014841:von Willebrand Factor; D051722:ADAM Proteins; D000071120:ADAMTS13 Protein; C099604:ADAMTS13 protein, human