title: Multifunctional bioconjugation by Morita-Baylis-Hillman reaction in aqueous medium.
abstract: An efficient approach for modular assembly of multifunctional bioconjugates from oligosaccharides, peptides and proteins with fluorescent probes/affinity tags based on Morita-Baylis-Hillman (MBH) reaction in aqueous medium has been developed.
authors.affiliation: State Key Laboratory of Chirosciences and Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, China.
authors.forename: Gai-Li
authors.initials: GL
authors.lastname: Li
authors.forename: Karen Ka-Yan
authors.initials: KK
authors.lastname: Kung
authors.forename: Lan
authors.initials: L
authors.lastname: Zou
authors.forename: Hiu-Chi
authors.initials: HC
authors.lastname: Chong
authors.forename: Yun-Chung
authors.initials: YC
authors.lastname: Leung
authors.forename: Ka-Hing
authors.initials: KH
authors.lastname: Wong
authors.forename: Man-Kin
authors.initials: MK
authors.lastname: Wong
mesh_terms: D000447:Aldehydes / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000737:chemistry; D007659:Ketones / Q000737:chemistry*; D009842:Oligopeptides / Q000737:chemistry; D055601:Organic Chemistry Phenomena; D010879:Piperazines / Q000737:chemistry; D011887:Raffinose / Q000737:chemistry*; D012710:Serum Albumin, Bovine / Q000737:chemistry
chemical_list: D000447:Aldehydes; D005456:Fluorescent Dyes; D007659:Ketones; D009842:Oligopeptides; D010879:Piperazines; D012710:Serum Albumin, Bovine; D011887:Raffinose; C007306:triethylenediamine