title: Normal values of real-time 3-dimensional echocardiographic parameters in a healthy Japanese population: the JAMP-3D Study.
abstract: BACKGROUND
  The recently developed real-time 3-dimensional echocardiography (RT3DE) is a promising imaging method to quantify cardiac chamber volumes and their functions in clinical practice. However, normal reference values of RT3DE parameters have not been fully investigated in a large, healthy Japanese population.
  
  
  RESULTS
  This study consisted of 410 healthy subjects aged from 20 to 69 years who had a RT3DE at one of the 23 collaborating institutions. All subjects had no history of cardiac disease and no risk factors. The mean values in men and women were as follows: 50 ± 12 ml/m(2) and 46 ± 9 ml/m(2) for left ventricular (LV) end-diastolic volume index, 19 ± 5 ml/m(2) and 17 ± 4 ml/m(2) for end-systolic volume index, 61 ± 4% and 63 ± 4% for ejection fraction, 64 ± 1 2 g/m(2) and 56 ± 11 g/m(2) for mass index, 23 ± 6 ml/m(2) and 24 ± 6 ml/m(2) for left atrial (LA) maximum volume index, 10 ± 3 ml/m(2) and 10 ± 3 ml/m(2) for minimum volume index, and 58 ± 6% and 58 ± 6% for percent volume change. LV sizes decreased with age, whereas LV mass index did not change. LA sizes slightly increased with age.
  
  
  CONCLUSIONS
  This multicenter investigation determined normal reference values for LV and LA sizes, and their functional parameters on RT3DE in a large, healthy Japanese population. The results of the present study support the use of RT3DE for the diagnosis and management of cardiovascular disease.
authors.affiliation: Department of Medicine, Osaka Ekisaikai Hospital, 2-1-10 Honden, Nishi-ku, Osaka 550-0022, Japan. h-syouta@mve.biglobe.ne.jp
authors.forename: Shota
authors.initials: S
authors.lastname: Fukuda
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Watanabe
authors.forename: Masao
authors.initials: M
authors.lastname: Daimon
authors.forename: Yukio
authors.initials: Y
authors.lastname: Abe
authors.forename: Akihiro
authors.initials: A
authors.lastname: Hirashiki
authors.forename: Kumiko
authors.initials: K
authors.lastname: Hirata
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Ito
authors.forename: Masumi
authors.initials: M
authors.lastname: Iwai-Takano
authors.forename: Katsuomi
authors.initials: K
authors.lastname: Iwakura
authors.forename: Chisato
authors.initials: C
authors.lastname: Izumi
authors.forename: Takayuki
authors.initials: T
authors.lastname: Hidaka
authors.forename: Toshinori
authors.initials: T
authors.lastname: Yuasa
authors.forename: Kazuya
authors.initials: K
authors.lastname: Murata
authors.forename: Satoshi
authors.initials: S
authors.lastname: Nakatani
authors.forename: Kazuaki
authors.initials: K
authors.lastname: Negishi
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Nishigami
authors.forename: Tomoko
authors.initials: T
authors.lastname: Nishikage
authors.forename: Takahiro
authors.initials: T
authors.lastname: Ota
authors.forename: Akihiro
authors.initials: A
authors.lastname: Hayashida
authors.forename: Konomi
authors.initials: K
authors.lastname: Sakata
authors.forename: Nobuhiro
authors.initials: N
authors.lastname: Tanaka
authors.forename: Satoshi
authors.initials: S
authors.lastname: Yamada
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Yamamoto
authors.forename: Junichi
authors.initials: J
authors.lastname: Yoshikawa
mesh_terms: D000328:Adult; D000368:Aged; D044466:Asian People; D002318:Cardiovascular Diseases / Q000000981:diagnostic imaging / Q000473:pathology / Q000503:physiopathology; D019560:Echocardiography, Three-Dimensional; D006352:Heart Ventricles / Q000000981:diagnostic imaging*; D006801:Humans; D007564:Japan; D008297:Male; D008875:Middle Aged; D009929:Organ Size / Q000502:physiology; D013318:Stroke Volume / Q000502:physiology*; D016277:Ventricular Function, Left / Q000502:physiology*