title: Prevalence and clinical impact of eating disorders in bipolar patients.
abstract: OBJECTIVE
  To study the impact of eating disorders (EDs) on the severity of bipolar disorder (BD).
  
  
  METHODS
  The Structured Clinical Interview for DSM-IV Axis I (SCID-I), Young Mania Rating Scale (YMRS), Hamilton Depression Rating Scale (HAM-D-17), Hamilton Anxiety Rating Scale (HAM-A), Global Assessment of Functioning (GAF), Clinical Global Impression (CGI), and the World Health Organization Quality of Life Assessment (WHOQOL-BREF) were used. Clinical and sociodemographic data were also collected.
  
  
  RESULTS
  Among the 356 bipolar patients included in this study, 19 (5.3%) were also diagnosed with ED. Of these, 57.9% had bulimia nervosa (BN) and 42.1% had anorexia nervosa (AN). Among ED patients, 94.7% were female. Bipolar patients with EDs presented with lower scores in the mental health domain of the WHOQOL-BREF, higher scores of depressive symptoms, and more psychiatric comorbidities.
  
  
  CONCLUSIONS
  ED comorbidities imposed important negative outcomes in bipolar patients. This finding suggests that attention should be given to the presence of EDs in BD patients and that better treatments focused on this population should be developed.
authors.affiliation: Center for the Study of Mood and Anxiety Disorders, University Hospital, Universidade Federal da Bahia, Salvador, Brazil.
authors.forename: Camila
authors.initials: C
authors.lastname: Seixas
authors.forename: Angela
authors.initials: A
authors.lastname: Miranda-Scippa
authors.forename: Fabiana
authors.initials: F
authors.lastname: Nery-Fernandes
authors.forename: Mônica
authors.initials: M
authors.lastname: Andrade-Nascimento
authors.forename: Lucas C
authors.initials: LC
authors.lastname: Quarantini
authors.forename: Flavio
authors.initials: F
authors.lastname: Kapczinski
authors.forename: Irismar Reis de
authors.initials: IR
authors.lastname: Oliveira
mesh_terms: D000328:Adult; D000856:Anorexia Nervosa / Q000453:epidemiology / Q000523:psychology*; D001714:Bipolar Disorder / Q000453:epidemiology / Q000523:psychology*; D052018:Bulimia Nervosa / Q000453:epidemiology / Q000523:psychology*; D015897:Comorbidity; D005260:Female; D006801:Humans; D008297:Male; D015995:Prevalence