title: Inhibitors of apoptosis proteins and IL-1β: a tangled relationship.
abstract: Inhibitors of apoptosis proteins (IAPs) are important regulators of both cell death and inflammation. In this issue of Immunity, Vince et al. (2012) report that inhibition of IAPs results in the processing and secretion of IL-1β through RIP3-mediated caspase-1- and caspase-8-dependent pathways.
authors.affiliation: Inflammation Program, Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA.
authors.forename: Ceren
authors.initials: C
authors.lastname: Ciraci
authors.forename: Fayyaz S
authors.initials: FS
authors.lastname: Sutterwala