title: [Trends in the prevalence of malaria and anemia at delivery in Libreville from 1995 to 2011].
abstract: In 1995, 2005 and 2011, cross-sectional studies of 611 parturients at the Centre Hospitalier de Libreville in Gabon assessed the prevalence of maternal malaria and anaemia; two indicators of poor pregnancy outcomes. The prevalence of Plasmodium falciparum infection in maternal peripheral blood decreased from 25% in 2005 to 6% in 2011. Parasite density was significantly lower in 2005 (31 p/μL) than in 1995 (1,240 p/μL) or 2011 (35,055 p/μL). Anaemia prevalence was high (>50%) in 1995 and in 2005, but fell by more than 50% (24%) in 2011. After implementation of new malaria prevention strategies during pregnancy, the prevalence of both maternal peripheral P. falciparum infection and anaemia fell. Studies are necessary to assess the efficacy of these strategies and to seek other causes of anaemia.
authors.affiliation: Université des Sciences de la Santé, Faculté de Médecine, Département de Parasitologie-Mycologie, BP 4009 Libreville, Gabon. mariellebouyou@gmail.com
authors.forename: Marielle Karine
authors.initials: MK
authors.lastname: Bouyou-Akotet
authors.forename: Solange
authors.initials: S
authors.lastname: Nzenze-Afène
authors.forename: Denise Patricia
authors.initials: DP
authors.lastname: Mawili-Mboumba
authors.forename: Mathieu
authors.initials: M
authors.lastname: Owono-Medang
authors.forename: Vincent
authors.initials: V
authors.lastname: Guiyedi
authors.forename: Maryvonne
authors.initials: M
authors.lastname: Kombila
mesh_terms: D000293:Adolescent; D000328:Adult; D000740:Anemia / Q000453:epidemiology*; D000962:Antimalarials / Q000627:therapeutic use; D018890:Chemoprevention; D002738:Chloroquine / Q000627:therapeutic use; D003430:Cross-Sectional Studies; D005260:Female; D005681:Gabon / Q000453:epidemiology; D006454:Hemoglobins / Q000378:metabolism; D006801:Humans; D016778:Malaria, Falciparum / Q000453:epidemiology* / Q000517:prevention & control; D008875:Middle Aged; D018512:Parasitemia / Q000453:epidemiology; D010298:Parity; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000453:epidemiology*; D015597:Pregnancy Complications, Parasitic / Q000453:epidemiology*; D015995:Prevalence; D055815:Young Adult
chemical_list: D000962:Antimalarials; D006454:Hemoglobins; D002738:Chloroquine