title: Enantioselective synthesis of (-)-paeonilide.
abstract: The first enantioselective synthesis of (-)-paeonilide is reported. Starting from inexpensive furan-3-carboxylic acid the targeted monoterpene was obtained in 12 steps via an asymmetric cyclopropanation-lactonization cascade and a stereoselective side chain insertion at an acetal-like position.
authors.affiliation: Institut für Organische Chemie, Universität Regensburg, Universitätsstr. 31, 93053 Regensburg, Germany.
authors.forename: Klaus
authors.initials: K
authors.lastname: Harrar
authors.forename: Oliver
authors.initials: O
authors.lastname: Reiser
mesh_terms: D001688:Biological Products / Q000138:chemical synthesis* / Q000737:chemistry; D005663:Furans / Q000737:chemistry*; D029596:Paeonia; D018517:Plant Roots; D013237:Stereoisomerism; D013729:Terpenes / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D001688:Biological Products; D005663:Furans; D013729:Terpenes; C416702:paeonilide