title: Clinical significance of serum CA125 in nephrotic syndrome.
abstract: BACKGROUND
  To investigate the clinical significance of serum CA125 in the patients with nephrotic syndrome (NS).
  
  
  METHODS
  Three hundred and twenty-two patients with NS and 120 healthy volunteers were enrolled in our study. We measured serum CA125 and analyzed the probable relationship between elevated CA-125 levels in patients with NS, with and without ascites. Ascites were determined by B-mode ultrasonography in patients with NS.
  
  
  RESULTS
  Serum CA-125 in NS patients with ascites was significantly increased compared to NS patients without ascites (p < 0.05). There was no statistically significant difference between the healthy volunteers and the patients without ascites (p > 0.05).
  
  
  CONCLUSIONS
  Serum CA125 is a useful index in the diagnosis of ultrasonographically detected ascites in patients with NS.
authors.affiliation: Department of Nephrology, Shandong University Qilu Hospital, Jinan, China. sesame_oil@126.com
authors.forename: Tao
authors.initials: T
authors.lastname: Peng
authors.forename: Ling
authors.initials: L
authors.lastname: Guo
authors.forename: Qing
authors.initials: Q
authors.lastname: Xia
authors.forename: Xiangdong
authors.initials: X
authors.lastname: Yang
mesh_terms: D001201:Ascites / Q000097:blood / Q000175:diagnosis* / Q000209:etiology; D015415:Biomarkers / Q000097:blood; D018394:CA-125 Antigen / Q000097:blood*; D005260:Female; D006801:Humans; D008297:Male; D008565:Membrane Proteins / Q000097:blood*; D008875:Middle Aged; D009404:Nephrotic Syndrome / Q000097:blood / Q000175:diagnosis*
chemical_list: D015415:Biomarkers; D018394:CA-125 Antigen; C451759:MUC16 protein, human; D008565:Membrane Proteins