title: Abnormal glucose metabolism in Hispanic parents of children with acanthosis nigricans.
abstract: Objective. Assess the prevalence of abnormal glucose metabolism among Hispanic parents of children with acanthosis nigricans (AN). Methods. Hispanic families (n = 258) were evaluated for metabolic and anthropometric parameters including fasting glucose levels and AN status. Results. Mothers with AN+ children had IFG (17.3%) and 4% had glucose levels ≥126 mg/dL (P = 0.028) compared to 7.1% and 1.8% of mothers with AN- children, respectively. Mothers of AN+ children also had greater odds of having impaired fasting glucose levels (OR: 3.917, 95% CI: 1.475-10.404; P < 0.004) but this was not the case for fathers (OR: 1.125, 95% CI: 0.489-2.586; P = 0.781). Mothers of AN+ children were also more likely to be AN+ (OR: 5.76, 95% CI: 2.98-11.13, P < 0.001). Screening discovered glucose levels >126 mg/dL in 9% of fathers with AN+ children. Conclusions. Hispanic mothers of AN+ children are at higher risk of carbohydrate metabolism abnormalities. AN in children can be a marker for prevention and delay programs aimed at identifying adults at risk for diabetes.
authors.affiliation: Department of Management, Policy, and Community Health, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.
authors.forename: Ximena
authors.initials: X
authors.lastname: Urrutia-Rojas
authors.forename: Walter
authors.initials: W
authors.lastname: McConathy
authors.forename: Benjamin
authors.initials: B
authors.lastname: Willis
authors.forename: John
authors.initials: J
authors.lastname: Menchaca
authors.forename: Mary
authors.initials: M
authors.lastname: Luna-Hollen
authors.forename: Khiya
authors.initials: K
authors.lastname: Marshall
authors.forename: Andras
authors.initials: A
authors.lastname: Lacko
authors.forename: Craig
authors.initials: C
authors.lastname: Spellman