title: Regulatory T cells stay on course.
abstract: Regulatory T (Treg) cells are thought to be susceptible to conversion into effector T cells. In this issue of Immunity, Miyao et al. (2012) provide evidence that the apparent plasticity of murine Foxp3(+) Treg cells is largely restricted to a defined subset of poorly committed Foxp3(+) cells.
authors.affiliation: Experimental Rheumatology, Charité Universitätsmedizin Berlin and Deutsches Rheuma-Forschungszentrum Berlin, 10117 Berlin, Germany. hamann@drfz.de
authors.forename: Alf
authors.initials: A
authors.lastname: Hamann