title: Intrauterine blood transfusion in immune hydrops fetalis, corrects middle cerebral artery Doppler velocimetry very quickly.
abstract: The aim of our study was to evaluate the middle cerebral artery velocimetry before and after intrauterine blood transfusion in immune hydrops fetalis. The current study was conducted in a tertiary research hospital, from February 2009 to January 2011. Nineteen intrauterine blood transfusions performed during the study period. The factors recorded were age of the mothers, gestational weeks, pre-transfusion fetal hematocrit and post-transfusion fetal hematocrit, and also middle cerebral artery peak systolic velocimetry (MCA-PSV) was detected and recorded before and after intrauterine transfusion. A control group of twenty two cases for normal MCA doppler velocimetry was also included to the study. During the study, a total of eleven rhesus isoimmunized pregnancies underwent intrauterine blood transfusions at our perinatal diagnose unit. Before transfusion seventeen severe and two moderate anemias were detected and mean MoM of MCA-PSV was 1.76±0.38 MoM. Post transfusion mean MoM of MCA-PSV in the patient group and control group were 1.08±0.22 MoM and 0.96±0.21 MoM, respectively. The mean MCA-PSV values were higher in RI fetuses than post transfusion and control group. In current study, we found that MCA-PSV is a valuable parameter in detecting fetal anemia requiring intrauterine transfusion and mean MCA-PSV values is higher than 1.5 MoM in fetuses with anemia. And also decrease in MCA-PSV just after transfusion in anemic fetuses showed the quick response of the fetus to correction of anemia.
authors.affiliation: Department of Obstetrics and Gynecology, School of Medicine, Dicle University, Diyarbakir, Turkey.
authors.forename: Ahmet
authors.initials: A
authors.lastname: Yalinkaya
authors.forename: Mehmet
authors.initials: M
authors.lastname: Sıddık Evsen
authors.forename: Yusuf
authors.initials: Y
authors.lastname: Celik
authors.forename: Muhammet
authors.initials: M
authors.lastname: Erdal Sak
authors.forename: Hatice
authors.initials: H
authors.lastname: Ender Soydinc
authors.forename: Mehmet
authors.initials: M
authors.lastname: Zeki Taner
mesh_terms: D000328:Adult; D001783:Blood Flow Velocity; D001805:Blood Transfusion, Intrauterine; D016022:Case-Control Studies; D005260:Female; D006400:Hematocrit; D006801:Humans; D015160:Hydrops Fetalis / Q000097:blood / Q000503:physiopathology / Q000628:therapy*; D020768:Middle Cerebral Artery / Q000503:physiopathology*; D011247:Pregnancy; D011446:Prospective Studies; D012212:Rheology