title: Pulmonary mucosa-associated lymphoid tissue (MALT) lymphoma in Sjögren's syndrome showing only the LIP pattern radiologically.
abstract: A 49-year-old woman with a 20-year history of Sjögren's syndrome (SS) was incidentally found to have an abnormal chest X-ray along with dyspnea and desaturation. Chest CT findings showed multiple cystic shadows, ground glass opacity, and small nodule-like lymphocytic interstitial pneumonia (LIP), which have been previously reported. She was diagnosed by surgical lung biopsy to have mucosa-associated lymphoid tissue (MALT) lymphoma. It was difficult to detect the presence of lymphoma by the use of only CT findings. Pulmonary involvement of SS occurs in various forms so that SS patients with pulmonary involvement should undergo open biopsy to reach a definitive diagnosis.
authors.affiliation: Division of Pulmonary Medicine, Saitama Medical Center, Jichi Medical University, Japan. yasuyasu@omiya.jichi.ac.jp
authors.forename: Yasutaka
authors.initials: Y
authors.lastname: Watanabe
authors.forename: Shinichiro
authors.initials: S
authors.lastname: Koyama
authors.forename: Chihiro
authors.initials: C
authors.lastname: Miwa
authors.forename: Shinya
authors.initials: S
authors.lastname: Okuda
authors.forename: Yoshihiko
authors.initials: Y
authors.lastname: Kanai
authors.forename: Kenji
authors.initials: K
authors.lastname: Tetsuka
authors.forename: Mitsuhiro
authors.initials: M
authors.lastname: Nokubi
authors.forename: Yoh
authors.initials: Y
authors.lastname: Dobashi
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Kawabata
authors.forename: Yoshinobu
authors.initials: Y
authors.lastname: Kanda
authors.forename: Shunsuke
authors.initials: S
authors.lastname: Endo
mesh_terms: D058846:Antibodies, Monoclonal, Murine-Derived / Q000008:administration & dosage; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000627:therapeutic use; D001706:Biopsy; D003520:Cyclophosphamide / Q000008:administration & dosage; D003937:Diagnosis, Differential; D004317:Doxorubicin / Q000008:administration & dosage; D005260:Female; D006801:Humans; D008168:Lung / Q000473:pathology; D017563:Lung Diseases, Interstitial / Q000000981:diagnostic imaging* / Q000209:etiology*; D008175:Lung Neoplasms / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000209:etiology*; D018442:Lymphoma, B-Cell, Marginal Zone / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000209:etiology*; D008875:Middle Aged; D011241:Prednisone / Q000008:administration & dosage; D013902:Radiography, Thoracic; D000069283:Rituximab; D012859:Sjogren's Syndrome / Q000150:complications*; D016896:Treatment Outcome; D014750:Vincristine / Q000008:administration & dosage
chemical_list: D058846:Antibodies, Monoclonal, Murine-Derived; C571759:R-CHOP protocol; D000069283:Rituximab; D014750:Vincristine; D004317:Doxorubicin; D003520:Cyclophosphamide; D011241:Prednisone