title: [Drug's administration via feeding tubes: evaluation of practices in an intensive care unit of a Tunisian hospital].
abstract: BACKGROUND
  Drugs' administration via feeding tubes is a potential source of iatrogenic events for the intensive care patients because of the problem of not adapted galenic forms.
  
  
  OBJECTIVE
  We analyzed the prescriptions of patients with enteral feedings to determine if the galenic forms were compatible with administration via feeding tubes. We also observed and analyzed the methods of drugs passage by nurses.
  
  
  METHODS
  We analyzed 30 prescriptions of patients with enteral feedings in the intensive care unit of Habib Bourguiba Sfax hospital, by a prospective and exhaustive way. We also, observed and evaluated the practices of preparation and administration of drugs to these patients via feeding tube by nurses.
  
  
  RESULTS
  Only 12% of drugs were liquids. Eighty-eight percent of the drugs were pulverised and capsule open before administration. The galenic form was not in conformity for 20% of drugs because of the prohibition to crushing tablet or opening capsule (gastroresistant form was dissolved), or because of the administration of a parenteral form (risk of irritation). Among 78 drugs administered by 10 different nurses, the time between passage of the drug and enteral nutrition were not respected for 59% of the observations. The drugs were managed in mixture for 90% of the observations. The gloves were not worn in 80% of observations. No rinsing is made between consecutive administrations and before administration.
  
  
  CONCLUSIONS
  This study shows that it is possible to reduce risk of administration errors in the intensive care unit and to facilitate the administration of drug via feeding tube by prescribing liquid oral form or soluble solid oral form. It also shows the need for cooperation with the pharmacist in order to adapt the galenic forms and to redact protocol of administration.
authors.affiliation: Service de pharmacie, CHU Habib Bourguiba, Sfax, Tunisie. emna_zt@yahoo.fr
authors.forename: E
authors.initials: E
authors.lastname: Triki
authors.forename: S
authors.initials: S
authors.lastname: Fendri
authors.forename: H
authors.initials: H
authors.lastname: Dammak
authors.forename: M
authors.initials: M
authors.lastname: Bouaziz
authors.forename: S
authors.initials: S
authors.lastname: Sfar
mesh_terms: D002214:Capsules; D003422:Critical Care / Q000379:methods*; D004333:Drug Administration Routes; D004339:Drug Compounding; D011307:Drug Prescriptions; D004750:Enteral Nutrition / Q000295:instrumentation* / Q000451:nursing; D006801:Humans; D007362:Intensive Care Units / Q000706:statistics & numerical data; D008508:Medication Errors / Q000517:prevention & control; D011208:Powders; D057184:Practice Patterns, Nurses' / Q000706:statistics & numerical data; D011446:Prospective Studies; D012996:Solutions / Q000008:administration & dosage; D014416:Tunisia
chemical_list: D002214:Capsules; D011208:Powders; D012996:Solutions