title: Levofloxacin-induced delirium: is it a dangerous drug in patients with renal dysfunction?
abstract: The central nervous system (CNS) toxicity of fluoroquinolones is well known but usually occurs benign. In the literature, there are a few number of severe CNS toxicity cases related to fluoroquinolones. Levofloxacin is a third-generation fluorinated quinolone antibiotic, is the active levo stereoisomer of ofloxacin, and has one of the most favorable adverse reaction profiles. We describe a case of delirium associated with levofloxacin in a 55-year-old man who was hospitalized in our medical clinic for pneumonia.
authors.affiliation: Department of Nephrology, Erciyes University Medical Faculty, Kayseri, Turkey. iikocyigit@gmail.com
authors.forename: Ismail
authors.initials: I
authors.lastname: Kocyigit
authors.forename: Sumeyra
authors.initials: S
authors.lastname: Dortdudak
authors.forename: Murat
authors.initials: M
authors.lastname: Sipahioglu
authors.forename: Aydin
authors.initials: A
authors.lastname: Unal
authors.forename: Hasan Esat
authors.initials: HE
authors.lastname: Yucel
authors.forename: Bulent
authors.initials: B
authors.lastname: Tokgoz
authors.forename: Eray
authors.initials: E
authors.lastname: Eroglu
authors.forename: Oktay
authors.initials: O
authors.lastname: Oymak
authors.forename: Cengiz
authors.initials: C
authors.lastname: Utas
mesh_terms: D000900:Anti-Bacterial Agents / Q000009:adverse effects; D003693:Delirium / Q000139:chemically induced* / Q000175:diagnosis; D005500:Follow-Up Studies; D006801:Humans; D064704:Levofloxacin; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D015242:Ofloxacin / Q000009:adverse effects* / Q000627:therapeutic use; D011014:Pneumonia / Q000150:complications / Q000000981:diagnostic imaging / Q000188:drug therapy; D051437:Renal Insufficiency / Q000150:complications*; D014057:Tomography, X-Ray Computed
chemical_list: D000900:Anti-Bacterial Agents; D064704:Levofloxacin; D015242:Ofloxacin