title: Heterogeneity of multiple-pore membranes investigated with ion conductance microscopy.
abstract: Heterogeneous conductance of individual pores on a porous membrane was studied with a four-electrode scanning ion conductance microscope (SICM). Application of a potential difference across the membrane resulted in migration of ions through nanopores, where subsequent conductance changes were measured by a nanopipet positioned above the nanopore as a change in pipet current. Current responses of single-pore membranes and individual pores within a multipore membrane were examined and demonstrated variations in ion current rectification (ICR) ratios due to the small differences in pore geometries.
authors.affiliation: Department of Chemistry, Indiana University, Bloomington, Indiana 47405, United States.
authors.forename: Yi
authors.initials: Y
authors.lastname: Zhou
authors.forename: Chiao-Chen
authors.initials: CC
authors.lastname: Chen
authors.forename: Lane A
authors.initials: LA
authors.lastname: Baker
mesh_terms: D004553:Electric Conductivity; D004566:Electrodes; D004867:Equipment Design; D007477:Ions / Q000737:chemistry*; D008567:Membranes, Artificial; D008853:Microscopy / Q000295:instrumentation*; D058608:Nanopores / Q000648:ultrastructure*; D016062:Porosity
chemical_list: D007477:Ions; D008567:Membranes, Artificial