title: [Preventive bone mineral density measurement in postmenopausal women. Differentiation of treatment of recommendations Guidelines of the Umbrella Organization for Osteology ("Dachverband Osteologie")].
abstract: BACKGROUND
  Osteopenia (OP) or osteoporosis (OST) was diagnosed by bone densitometry (DXA) in postmenopausal women free of known skeletal disorders and without acute fracture. DVO guidelines were applied to define therapeutic indication.
  
  
  METHODS
  The study included 94 women aged 59-81 years. Fracture or operation ≤12 months, malignant tumor, ovariectomy, and drugs such as cortisone, strontium, fluorides, bisphosphonates, SERMs, estrogens, and steroids were exclusion criteria. The lowest T-score at the spine, femoral neck, or total hip was decisive. The indication for therapy was determined by evaluating age, BMD, and other risk factors.
  
  
  RESULTS
  Using the WHO criteria 22.3% (n=21) had normal BMD, 52.1% (n=49) had OP, and 25.6% (n=24) had OST. According to "Dachverband Osteologie" (DVO) guidelines, 28 women (29.8%) of the whole group needed therapy. Of the 28 women receiving therapy, 9 had OP and 19 had OST. Therapy was indicated in 18.4% for OP and 79.2% for OST.
  
  
  CONCLUSIONS
  A preventive measurement of BMD with DXA provides a benefit for postmenopausal women. Combinatory assessment and consideration of other risk factors allows identification of women who might benefit from early treatment.
authors.affiliation: Klinik für Unfallchirurgie, Universitätsklinikum Magdeburg A.ö.R., Leipziger Straße 44, 39120, Magdeburg, Deutschland. stefan.piatek@med.ovgu.de
authors.forename: S
authors.initials: S
authors.lastname: Piatek
authors.forename: T
authors.initials: T
authors.lastname: Wex
authors.forename: D
authors.initials: D
authors.lastname: Adolf
authors.forename: S
authors.initials: S
authors.lastname: Klose
authors.forename: S
authors.initials: S
authors.lastname: Westphal
authors.forename: H
authors.initials: H
authors.lastname: Amthauer
authors.forename: W
authors.initials: W
authors.lastname: Halangk
authors.forename: O
authors.initials: O
authors.lastname: Jahn
authors.forename: C
authors.initials: C
authors.lastname: Riebau
authors.forename: S
authors.initials: S
authors.lastname: Winckler
mesh_terms: D015502:Absorptiometry, Photon / Q000592:standards* / Q000706:statistics & numerical data; D000368:Aged; D000369:Aged, 80 and over; D015519:Bone Density; D050071:Bone Density Conservation Agents / Q000627:therapeutic use*; D015897:Comorbidity; D005260:Female; D005858:Germany / Q000453:epidemiology; D006801:Humans; D008297:Male; D008403:Mass Screening / Q000592:standards* / Q000706:statistics & numerical data; D008875:Middle Aged; D059166:Osteology / Q000592:standards*; D015663:Osteoporosis, Postmenopausal / Q000175:diagnosis* / Q000453:epidemiology / Q000517:prevention & control*; D058866:Osteoporotic Fractures / Q000453:epidemiology / Q000517:prevention & control; D017410:Practice Guidelines as Topic; D015995:Prevalence; D015203:Reproducibility of Results; D012307:Risk Factors; D012680:Sensitivity and Specificity
chemical_list: D050071:Bone Density Conservation Agents