title: [Neuropsychiatric symptoms in older adults with and without dementia in urban and rural regions. Results of the 10/66 Dementia Research Group in Mexico].
abstract: OBJECTIVE
  To describe, in a Mexican sample of urban and rural residents older than 65 years, with and without dementia, the frequency and severity of neuropsychiatric symptoms.
  
  
  METHODS
  This work is part of the multi-center, epidemiological study carried out by the 10/66 Dementia Research Group, with 1,003 subjects from an urban region and 1,000 subjects from a rural region. Neuropsychiatric symptoms were assessed with the abbreviated version of the Neuropsychiatric Inventory (NPI-Q).
  
  
  RESULTS
  Eighty six and eighty five dementia cases were found in the urban and rural regions, respectively. Subjects with dementia were more frequently widows, older and less educated, and the ones from the rural region had fewer neuropsychiatric symptoms, compared to the urban region. In both regions all symptoms were more severe in subjects with dementia. A high frequency of affective symptoms (depression and apathy specially) was observed, and irritability and anxiety in second term. The caregiver stress levels were associated with the frequency and severity of symptoms.
  
  
  CONCLUSIONS
  This is the first study reporting neuropsychiatric symptoms associated with dementia identified by means of culturally validated and population based diagnostic criteria, in Mexican residents of urban and rural settings.
authors.affiliation: * Departamento de Neuropsicología, Instituto Nacional de Neurología y Neurocirugía Manuel Velasco Suárez, México DF. yaneth_r@hotmail.com
authors.forename: Yaneth
authors.initials: Y
authors.lastname: Rodríguez-Agudelo
authors.forename: Rodolfo
authors.initials: R
authors.lastname: Solís-Vivanco
authors.forename: Isaac
authors.initials: I
authors.lastname: Acosta-Castillo
authors.forename: Nayeli
authors.initials: N
authors.lastname: García-Ramírez
authors.forename: Gabriela
authors.initials: G
authors.lastname: Rojas-de-la-Torre
authors.forename: Ana Luisa
authors.initials: AL
authors.lastname: Sosa
mesh_terms: D000342:Affective Symptoms / Q000453:epidemiology*; D000368:Aged; D000369:Aged, 80 and over; D001007:Anxiety / Q000453:epidemiology; D003704:Dementia / Q000453:epidemiology*; D003863:Depression / Q000453:epidemiology; D001068:Feeding and Eating Disorders / Q000453:epidemiology*; D005260:Female; D006212:Hallucinations / Q000453:epidemiology*; D006801:Humans; D007508:Irritable Mood; D008297:Male; D008800:Mexico / Q000453:epidemiology; D008875:Middle Aged; D009069:Movement Disorders / Q000453:epidemiology*; D010555:Personality Inventory; D012424:Rural Population / Q000706:statistics & numerical data*; D012893:Sleep Wake Disorders / Q000453:epidemiology*; D012959:Socioeconomic Factors; D011795:Surveys and Questionnaires; D014505:Urban Population / Q000706:statistics & numerical data*