title: [Indications for thrombolysis in ischemic stroke].
abstract: Cerebral MRI with angio-MR are more effective than CT scan for selecting patients with ischemic stroke for thrombolysis. The use of cerebral MRI has to be available 24h a day and everyday as a standardized emergency procedure. Off-label criteria for thrombolysis after acute ischemic stroke are too restritive and have to be revised. In acute ischemic stroke, imaging that shows the collateral circulation within the hypoperfusion area has to be used to estimate the potential of therapeutic revascularization. When there are contraindications for intravenous thrombolysis, the endovascular approach must be argued individually by neurologists and neurointerventionalists together.
authors.affiliation: Hôpital de Hautepierre, hôpitaux universitaires de Strasbourg, pôle tête et cou, unité neurovasculaire, 67098 Strasbourg cedex, France. valerie.wolff@chru-strasbourg.fr
authors.forename: Valérie
authors.initials: V
authors.lastname: Wolff
authors.forename: Valérie
authors.initials: V
authors.lastname: Lauer
authors.forename: Olivier
authors.initials: O
authors.lastname: Rouyer
authors.forename: Marc
authors.initials: M
authors.lastname: Bataillard
authors.forename: Christian
authors.initials: C
authors.lastname: Marescaux
mesh_terms: D013504:Cardiovascular Surgical Procedures; D000075202:Contraindications; D003657:Decision Making / Q000502:physiology; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D006801:Humans; D002546:Ischemic Attack, Transient / Q000000981:diagnostic imaging / Q000601:surgery / Q000628:therapy*; D008279:Magnetic Resonance Imaging; D018579:Patient Selection; D011859:Radiography; D020521:Stroke / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000601:surgery; D015912:Thrombolytic Therapy / Q000379:methods / Q000706:statistics & numerical data*
chemical_list: D005343:Fibrinolytic Agents