title: [Necessity of No.13 lymph node dissection in advanced gastric carcinoma].
abstract: OBJECTIVE
  To investigate the feasibility and necessity of No.13 lymph node dissection for advanced gastric carcinoma.
  
  
  METHODS
  Clinical data of 144 cases who were diagnosed as TNMII-III stage gastric carcinoma were collected from January 2007 to December 2009 in the Department of General Surgery at the First Affiliated Hospital of Nanchang University. Seventy-two cases who received D2 radical gastrectomy plus No.13 lymph node dissection were selected as the study group, and they were matched 1:1 to 72 cases who received D2 Radical gastrectomy (the control group) for TNMII-III stage gastric carcinoma. The differences in the intraoperative and postoperative parameters and survival time were compared, and the factors associated with No.13 lymph node metastasis were analyzed.
  
  
  RESULTS
  There were no significant differences between the two groups in operative time [(2.8 ± 0.4) h vs. (2.7 ± 0.4) h], blood loss [(191.9 ± 81.5) ml vs. (186.0 ± 81.7) ml], the incidence of postoperative complications (18.1% vs. 15.3%), length of hospital stay [(12.3 ± 4.2) d vs. (11.9 ± 3.2) d] and 3-year survival rate (63% vs. 57%) (all P>0.05). In the study group, there were 15 patients (20.8%) with positive No.13 lymph nodes, and the 3-year survival rate was 13%, significantly lower compared to those with negative No.13 lymph node (73%, n=57) (P<0.05). Multivariate analysis showed that N stage (P<0.01) and histological type (P<0.05) were independently associated with No.13 lymph node metastasis.
  
  
  CONCLUSIONS
  No.13 lymph node dissection for TNMII-III stage gastric cancer is feasible and necessary.
authors.affiliation: Department of Gastrointestinal Surgery, The First Affiliated Hospital, Nanchang University, Nanchang, China.
authors.forename: Gen
authors.initials: G
authors.lastname: Peng
authors.forename: Zhi-gang
authors.initials: ZG
authors.lastname: Jie
authors.forename: Zheng-rong
authors.initials: ZR
authors.lastname: Li
authors.forename: Yi
authors.initials: Y
authors.lastname: Liu
authors.forename: Xiao-ping
authors.initials: XP
authors.lastname: Xie
authors.forename: Sheng-quan
authors.initials: SQ
authors.lastname: Chen
authors.forename: Wei
authors.initials: W
authors.lastname: Li
authors.forename: Yi
authors.initials: Y
authors.lastname: Cao
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008197:Lymph Node Excision / Q000379:methods*; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D013274:Stomach Neoplasms / Q000601:surgery*