title: Deciduous molar hypomineralization and molar incisor hypomineralization.
abstract: This study was embedded in the Generation R Study, a population-based prospective cohort study from fetal life until young adulthood. This study focused on the relationship between Deciduous Molar Hypomineralization (DMH) and Molar Incisor Hypomineralization (MIH). First permanent molars develop during a period similar to that of second primary molars, with possible comparable risk factors for hypomineralization. Children with DMH have a greater risk of developing MIH. Clinical photographs of clean, moist teeth were taken with an intra-oral camera in 6,161 children (49.8% girls; mean age 74.3 mos, SD ± 5.8). First permanent molars and second primary molars were scored with respect to DMH or MIH. The prevalence of DMH and MIH was 9.0% and 8.7% at child level, and 4.0% and 5.4% at tooth level. The Odds Ratio for MIH based on DMH was 4.4 (95% CI, 3.1-6.4). The relationship between the occurrence of DMH and MIH suggests a shared cause and indicates that, clinically, DMH can be used as a predictor for MIH.
authors.affiliation: Department of Cariology, Endodontology and Pedodontology, Academic Centre for Dentistry Amsterdam, University of Amsterdam and VU University Amsterdam, Amsterdam, The Netherlands. m.elfrink@acta.nl
authors.forename: M E C
authors.initials: ME
authors.lastname: Elfrink
authors.forename: J M
authors.initials: JM
authors.lastname: ten Cate
authors.forename: V W V
authors.initials: VW
authors.lastname: Jaddoe
authors.forename: A
authors.initials: A
authors.lastname: Hofman
authors.forename: H A
authors.initials: HA
authors.lastname: Moll
authors.forename: J S J
authors.initials: JS
authors.lastname: Veerkamp
mesh_terms: D000566:Amelogenesis; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D003744:Dental Enamel Hypoplasia / Q000453:epidemiology / Q000209:etiology* / Q000473:pathology*; D019229:Dentition, Permanent; D005260:Female; D005544:Forecasting; D006801:Humans; D007180:Incisor / Q000002:abnormalities; D016015:Logistic Models; D008297:Male; D008963:Molar / Q000002:abnormalities*; D009426:Netherlands / Q000453:epidemiology; D016017:Odds Ratio; D023861:Photography, Dental; D015995:Prevalence; D011446:Prospective Studies; D012307:Risk Factors; D014094:Tooth, Deciduous / Q000002:abnormalities*