title: [CYP2E1 gene polymorphism and ovarian cancer risk in the Yakut population].
abstract: The CYP2E1 gene polymorphism has been studied in Yakut women with ovarian cancer and without cancer. The two groups have been found to substantially differ in the frequency of the CYP2E1* 1D allele (with a 96-bp insertion in the promoter region of the gene): it is more frequent in healthy women (16.3 versus 7.4%, P = 0.007).
authors.forename: A V
authors.initials: AV
authors.lastname: Khrunin
authors.forename: F G
authors.initials: FG
authors.lastname: Ivanova
authors.forename: A A
authors.initials: AA
authors.lastname: Moiseev
authors.forename: V A
authors.initials: VA
authors.lastname: Gorbunova
authors.forename: S A
authors.initials: SA
authors.lastname: Limborskaia
mesh_terms: D000483:Alleles; D019392:Cytochrome P-450 CYP2E1 / Q000235:genetics*; D005260:Female; D006801:Humans; D016254:Mutagenesis, Insertional; D010051:Ovarian Neoplasms / Q000453:epidemiology / Q000208:ethnology / Q000235:genetics*; D011110:Polymorphism, Genetic; D011401:Promoter Regions, Genetic / Q000235:genetics*; D012307:Risk Factors; D012800:Siberia / Q000453:epidemiology / Q000208:ethnology
chemical_list: D019392:Cytochrome P-450 CYP2E1