title: Effect of mannoproteins on the growth, gastrointestinal viability, and adherence to Caco-2 cells of lactic acid bacteria.
abstract: Yeast cell wall (YCW) preparations and yeast mannoprotein extracts have been effective against some enteropathogenic bacteria as Campylobacter jejuni, Escherichia coli, and Salmonella, and they can affect the population of beneficial lactic acid bacteria (LAB). In this work, we studied the effect of a mannoprotein extract on five strains of LAB. This extract was metabolised by the bacteria, enhancing their survival in simulated gastrointestinal juice, and increasing the adherence of Lactobacillus plantarum, L. salivarius, and Enterococcus faecium to Caco-2 cells. Yeast mannoproteins are promising naturally occurring compounds that could be used to enhance LAB intestinal populations and control pathogens.
authors.affiliation: Inst. de Fermentaciones Industriales (CSIC), Juan de la Cierva, 3. 28006, Madrid, Spain.
authors.forename: M
authors.initials: M
authors.lastname: Ganan
authors.forename: A V
authors.initials: AV
authors.lastname: Carrascosa
authors.forename: S
authors.initials: S
authors.lastname: de Pascual-Teresa
authors.forename: A J
authors.initials: AJ
authors.lastname: Martinez-Rodriguez
mesh_terms: D001422:Bacterial Adhesion / Q000187:drug effects*; D018938:Caco-2 Cells; D016123:Campylobacter jejuni / Q000187:drug effects; D015169:Colony Count, Microbial; D016984:Enterococcus faecium / Q000187:drug effects* / Q000254:growth & development; D004926:Escherichia coli / Q000187:drug effects; D041981:Gastrointestinal Tract / Q000382:microbiology*; D006801:Humans; D007778:Lactobacillus / Q000187:drug effects* / Q000254:growth & development; D008562:Membrane Glycoproteins / Q000494:pharmacology*; D019936:Probiotics / Q000378:metabolism
chemical_list: D008562:Membrane Glycoproteins; C025363:mannoproteins