title: [Morbidity and mortality of patients suffering from gestational trophoblastic diseases at the Clinic of Gynecology and Obstetrics, Clinical Center of Serbia in the period from 2000 to 2007].
abstract: BACKGROUND
  Gestational trophoblastic disease is a heterogenous group of diseases with malignant potential. The aim of this retrospective study was to evaluate potential risk factors in pathogenesis of gestational trophoblastic disease, its morbidity and mortality as well as treatment results.
  
  
  METHODS
  We investigated 82 patients who were treated at the University Clinic of Gynecology and Obstetrics Clinical Center of Serbia from Jan 1st 2000 to Dec 31st 2007. The data were collected from their hospital charts and referred to gynecological anamnesis, diagnosis, protocols of operated patients, diagnosis, histopathological findings, decisions of expert team for trophoblastic disease and hospital discharge.
  
  
  RESULTS
  The incidence was 1.5 per 1000 deliveries. The most frequent finding was hydatiform mole (59.8%). The patients were treated by chemotherapy and surgery. All patients survived.
  
  
  CONCLUSIONS
  The maternal age and a larger number deliveries and abortions are risk factor for gestational trophoblastic disease. The incidence in our clinic is approximately equal to the incidence in western countries in this period.
authors.affiliation: Klinicki centar Srbije, Beograd, Klinika za ginekologiju i akuserstvo. lazovic.biljana@gmail.com
authors.forename: Biljana
authors.initials: B
authors.lastname: Lazović
authors.forename: Vera
authors.initials: V
authors.lastname: Milenković
authors.forename: Ljiljana
authors.initials: L
authors.lastname: Mirković
mesh_terms: D000328:Adult; D005260:Female; D031901:Gestational Trophoblastic Disease / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy*; D006801:Humans; D011247:Pregnancy; D055771:Serbia / Q000453:epidemiology