title: Clinical and nutritional status in the late postoperative of pancreaticoduodenectomy: influence of pylorus preservation procedure.
abstract: OBJECTIVE
  To evaluate the nutritional status of patients in the late postoperative period of pancreaticoduodenectomy (PD) and compare the long-term outcome according to pylorus-preserving (PPPD) or the standard technique (SPD) in which the pylorus is resected.
  
  
  METHODS
  This prospective study was conducted twelve months prior or more in patients who had underwent PD (PD Group, n=15) and health volunteers (Control Group, n=15). At a post hoc analysis, the PD Group was divided in PPPD Subgroup (n=9) and SPD Subgroup (n=6), according to the PD techniques. Gastrointestinal complaints and nutritional status were evaluated, apart from a biochemical assessment; Student t-test or Mann-Whitney test were used.
  
  
  RESULTS
  The patients recovered their body weight and the gastrointestinal complaints were uncommon. The PD Group showed higher energy and protein intake even though BMI was lower than in Control Group. There were no differences in laboratorial data, except for higher glycemia, serum alkaline phosfatase and C-reactive protein in PD Group. There was no difference in the various parameters evaluated when the Subgroups (PPPD and SPD) were compared.
  
  
  CONCLUSIONS
  For long-term pancreaticoduodenectomy, the gastrointestinal symptoms are minimal and the patients had the clinical and nutritional status preserved, regardless of pylorus preservation.
authors.affiliation: Faculty of Medicine, Ribeirao Preto, SP, Brazil.
authors.forename: Cinara Knychala
authors.initials: CK
authors.lastname: Muniz
authors.forename: Camila Bitu Moreno
authors.initials: CB
authors.lastname: Braga
authors.forename: Rafael
authors.initials: R
authors.lastname: Kemp
authors.forename: José Sebastião dos
authors.initials: JS
authors.lastname: Santos
authors.forename: Selma Freire de Carvalho da
authors.initials: SF
authors.lastname: Cunha
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D001798:Blood Proteins; D015992:Body Mass Index; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009752:Nutritional Status / Q000502:physiology*; D016577:Pancreaticoduodenectomy / Q000379:methods*; D011184:Postoperative Period; D011446:Prospective Studies; D011708:Pylorus / Q000601:surgery*; D012737:Sex Factors; D018709:Statistics, Nonparametric; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D001798:Blood Proteins