title: Serum anti-Müllerian hormone is a better predictor of ovarian response than FSH and age in IVF patients with endometriosis.
abstract: OBJECTIVE
  To evaluate the ability of serum anti-Müllerian hormone (AMH), FSH, and age to clinically predict ovarian response to controlled ovarian hyperstimulation (COH) in IVF patients with endometriosis.
  
  
  METHODS
  We evaluated 91 COH cycles, including 43 cycles with endometriosis (group I) and 48 cycles with male factor infertility (group II) from January to December, 2010. Patients were classified into study groups based on their surgical history of endometriosis-group Ia (without surgical history, n=16), group Ib (with a surgical history, n=27).
  
  
  RESULTS
  The mean age was not significantly different between group I and group II. However, AMH and FSH were significantly different between group I and group II (1.9±1.9 ng/mL vs. 4.1±2.9 ng/mL, p<0.01; 13.1±7.2 mIU/mL vs. 8.6±3.3 mIU/mL, p<0.01). Furthermore, the number of retrieved oocytes and the number of matured oocytes were significantly lower in group I than in group II. In group II, AMH and FSH as well as age were significant predictors of retrieved oocytes on univariate analysis. Only the serum AMH level was a significant predictor of poor ovarian response in women with endometriosis.
  
  
  CONCLUSIONS
  Serum AMH may be a better predictor of the ovarian response of COH in patients with endometriosis than basal FSH or age. AMH level can be considered a useful clinical predictor of poor ovarian response in endometriosis patients.
authors.affiliation: Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Cheil General Hospital and Women's Healthcare Center, Kwandong University College of Medicine, Seoul, Korea.
authors.forename: Ji Hee
authors.initials: JH
authors.lastname: Yoo
authors.forename: Sun Hwa
authors.initials: SH
authors.lastname: Cha
authors.forename: Chan Woo
authors.initials: CW
authors.lastname: Park
authors.forename: Jin Young
authors.initials: JY
authors.lastname: Kim
authors.forename: Kwang Moon
authors.initials: KM
authors.lastname: Yang
authors.forename: In Ok
authors.initials: IO
authors.lastname: Song
authors.forename: Mi Kyoung
authors.initials: MK
authors.lastname: Koong
authors.forename: Inn Soo
authors.initials: IS
authors.lastname: Kang
authors.forename: Hye Ok
authors.initials: HO
authors.lastname: Kim