title: O-GlcNAcylation of a circadian clock protein: dPER taking its sweet time.
abstract: In this issue of Genes & Development, Kim and colleagues (pp. 490-502) report that the Drosophila circadian repressor dPER undergoes O-linked GlcNAcylation (O-GlcNAc). Their data show that manipulation of the relevant O-GlcNAc transferase (OGT) regulates behavioral rhythmicity by affecting the stability and nuclear translocation of dPER.
authors.affiliation: University of Heidelberg Biochemistry Center, Heidelberg, Germany.
authors.forename: Axel C R
authors.initials: AC
authors.lastname: Diernfellner
authors.forename: Michael
authors.initials: M
authors.lastname: Brunner
mesh_terms: D000818:Animals; D057906:Circadian Clocks / Q000502:physiology*; D004331:Drosophila melanogaster / Q000502:physiology*