title: Impact of genital warts on health related quality of life in men and women in mainland China: a multicenter hospital-based cross-sectional study.
abstract: BACKGROUND
  Information on the health-related quality of life (HRQoL) of patients with genital warts (GW) in populations in mainland China is still limited. The aim of the study was to use a generic instrument to measure the impact of genital warts on HRQoL in men and women in this setting.
  
  
  METHODS
  A multi-centre hospital-based cross-sectional study across 18 centers in China was conducted to interview patients using the European quality of life-5 dimension (EQ-5D) instrument; respondents' demographic and clinical data were also collected.
  
  
  RESULTS
  A total of 1,358 GW patients (612 men, 746 women) were included in the analysis, with a mean age of 32.0 ± 10.6 years. 56.4% of the patients reported some problems in the dimension of Anxiety/Depression (highest), followed by Pain/Discomfort (24.7%) and Mobility (3.5%). The overall visual analogue scale (VAS) score of the study population was found to be 65.2 ± 22.0, and the EQ-5D index score was found to be 0.843 ± 0.129 using Japanese preference weights (the Chinese preference was unavailable yet). Patients with lower VAS means and EQ-5D index scores were more often female, living in urban area, and suffering multiple GW (all p values < 0.05), but the values did not differ notably by age (p values > 0.05).
  
  
  CONCLUSIONS
  The HRQoL of patients with GW was substantially lower, compared to a national representative general population in China (VAS = ~80); the findings of different subgroups are informative for future GW prevention and control efforts.
authors.affiliation: Department of Cancer Epidemiology, Cancer Institute/Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, 17 South Panjiayuan LN, PO Box 2258, Beijing 100021, China.
authors.forename: Ju-Fang
authors.initials: JF
authors.lastname: Shi
authors.forename: Dian-Ju
authors.initials: DJ
authors.lastname: Kang
authors.forename: Shu-Zhen
authors.initials: SZ
authors.lastname: Qi
authors.forename: Hai-Yan
authors.initials: HY
authors.lastname: Wu
authors.forename: Yan-Chun
authors.initials: YC
authors.lastname: Liu
authors.forename: Li-Jun
authors.initials: LJ
authors.lastname: Sun
authors.forename: Li
authors.initials: L
authors.lastname: Li
authors.forename: Ying
authors.initials: Y
authors.lastname: Yang
authors.forename: Qing
authors.initials: Q
authors.lastname: Li
authors.forename: Xiang-Xian
authors.initials: XX
authors.lastname: Feng
authors.forename: Li-Qin
authors.initials: LQ
authors.lastname: Zhang
authors.forename: Jie
authors.initials: J
authors.lastname: Li
authors.forename: Xiao-Li
authors.initials: XL
authors.lastname: Li
authors.forename: Yun
authors.initials: Y
authors.lastname: Yang
authors.forename: Mayinuer
authors.initials: M
authors.lastname: Niyazi
authors.forename: Ai-Di
authors.initials: AD
authors.lastname: Xu
authors.forename: Jia-Hua
authors.initials: JH
authors.lastname: Liu
authors.forename: Qing
authors.initials: Q
authors.lastname: Xiao
authors.forename: Lian-Kun
authors.initials: LK
authors.lastname: Li
authors.forename: Xin-Zheng
authors.initials: XZ
authors.lastname: Wang
authors.forename: You-Lin
authors.initials: YL
authors.lastname: Qiao
mesh_terms: D000328:Adult; D017677:Age Distribution; D001007:Anxiety / Q000453:epidemiology / Q000523:psychology; D002681:China / Q000453:epidemiology; D003218:Condylomata Acuminata / Q000453:epidemiology / Q000517:prevention & control / Q000523:psychology*; D003430:Cross-Sectional Studies; D003863:Depression / Q000453:epidemiology / Q000523:psychology; D005260:Female; D006305:Health Status Indicators; D006801:Humans; D007407:Interviews as Topic; D008297:Male; D051346:Mobility Limitation; D010146:Pain / Q000150:complications / Q000453:epidemiology; D010147:Pain Measurement; D011788:Quality of Life; D012111:Residence Characteristics / Q000706:statistics & numerical data; D017678:Sex Distribution; D011795:Surveys and Questionnaires