title: What is the relationship between type 2 diabetes mellitus and urolithiasis?
abstract: OBJECTIVE
  Despite the high incidence of urolithiasis in general population, the exact underlying pathology is unknown. Possible association between urolithiasis and parameters of physical health were assesed in the presented study.
  
  
  METHODS
  The study was performed at an Internal Medicine out patient unit during routine check ups. Patients between the ages of 20 and 70 years were studied to prevent debility induced weight loss in elderly. Patients with devastating illnesses were excluded to avoid their possible effects on weight. Cases with urolithiasis were collected in one group, and age and sex-matched cases without urolithiasis were collected in other group.
  
  
  RESULTS
  Eighty cases with urolithiasis and 120 cases without were studied. Mean age of urolithiasis cases was 49.0 years, and 52.5 % of them were female. Mean weight of the urolithiasis cases was 76.0 kg, whereas it was 80.8 kg in the group without urolithiasis (p=0.013). The prevalence of type 2 diabetes mellitus (DM) was significantly higher in the urolithiasis group with unknown reasons (17.5 % vs 7.5 %, p<0.01). There was no significant difference as for the height, body mass index, prevalence of hypertension, and mean values of low density lipoprotein cholesterol, high density lipoprotein cholesterol, and triglyceride between the groups.
  
  
  CONCLUSIONS
  In spite of several terrible effects of excess weight on health, we could not detect any association with urolithiasis, but there is a highly significant association between urolithiasis and type 2 DM, and it may have hundreds of mechanisms with variable priorities, which must be explained with further studies (Tab. 1, Ref. 21). Full Text in free PDF www.bmj.sk.
authors.affiliation: Medical Faculty of the Mustafa Kemal University, Antakya, Turkey.
authors.forename: M
authors.initials: M
authors.lastname: Davarci
authors.forename: M R
authors.initials: MR
authors.lastname: Helvaci
authors.forename: M
authors.initials: M
authors.lastname: Aydin
mesh_terms: D000328:Adult; D000368:Aged; D015992:Body Mass Index; D003924:Diabetes Mellitus, Type 2 / Q000150:complications*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000150:complications; D052878:Urolithiasis / Q000150:complications*; D055815:Young Adult