title: Percutaneous approach in the maintenance and salvage of dysfunctional autologous vascular access for dialysis.
abstract: OBJECTIVE
  Endovascular procedures have been increasingly used for salvage of failing vascular access with conflicting results. The aim of this study was to assess the mid-term patency and complication rates of angioplasty procedures performed in a single center for treatment of stenosis compromising vascular accesses.
  
  
  METHODS
  A prospective database of vascular accesses performed in 2006-2010 was investigated. The endovascular approach was applied following a standardized protocol by a dedicated team. A total of 531 consecutive procedures were reviewed (326 men; mean age 70.94 years). Patency rates were estimated using the Kaplan-Meier method.
  
  
  RESULTS
  There were 199 procedures for failing access: 135 were surgical and 64 angioplasties performed for anastomosis (n=27), venous (n=45) or arterial (n=7) stenosis. Immediate technical success of endovascular procedures was 95.3%(61/64); complication rate was 6.3% (4/64). Primary patency rates were 55% at six months, 49% at 12 months, and 21% at 24 months. In the concurrent group of 135 open procedures, primary patency rates were 80% at six months and 67% at 12 months (P=.002); nevertheless, at 24 months, patency was as low as 49%. Cost estimates for angioplasty revealed additional fees ranging from 411.34 to 446.34 Euro with respect to open surgical procedures.
  
  
  CONCLUSIONS
  Most dysfunctional vascular accesses can be successfully and safely treated by the endovascular route. In spite of poor mid-term durability, the angioplasty balloon might be considered as a bridge, effective, and repeatable solution with reasonable costs to prolong access survival avoiding additional surgery. The failure rate in the mid-term for dysfunctional vascular access may also be high after surgical reintervention.
authors.affiliation: Unit of Vascular and Endovascular Surgery, Hospital S. M. Misericordia and University of Perugia, Perugia, Italy. pderango@unipg.it
authors.forename: Paola
authors.initials: P
authors.lastname: De Rango
authors.forename: Basso
authors.initials: B
authors.lastname: Parente
authors.forename: Enrico
authors.initials: E
authors.lastname: Cieri
authors.forename: Paolo
authors.initials: P
authors.lastname: Bonanno
authors.forename: Luca
authors.initials: L
authors.lastname: Farchioni
authors.forename: Alessandra
authors.initials: A
authors.lastname: Manzone
authors.forename: Fabio
authors.initials: F
authors.lastname: Verzini
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000800:Angioplasty, Balloon / Q000009:adverse effects / Q000191:economics; D001166:Arteriovenous Shunt, Surgical / Q000009:adverse effects* / Q000191:economics; D003251:Constriction, Pathologic; D005260:Female; D006083:Graft Occlusion, Vascular / Q000000981:diagnostic imaging / Q000191:economics / Q000209:etiology / Q000503:physiopathology / Q000628:therapy*; D017048:Health Care Costs; D006801:Humans; D053208:Kaplan-Meier Estimate; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011859:Radiography; D006435:Renal Dialysis / Q000191:economics; D012086:Reoperation; D013997:Time Factors; D016896:Treatment Outcome; D014654:Vascular Patency; D055815:Young Adult