title: Inheritance and memory of stress-induced epigenome change: roles played by the ATF-2 family of transcription factors.
abstract: Data on the inheritance-of-stress effect have been accumulating and some mechanistic insights, such as epigenetic regulation, have also been suggested. In particular, the modern view of Lamarckian inheritance appears to be affected by the finding that stress-induced epigenetic changes can be inherited. This review summarizes the current data on the inheritance of stress effect and possible mechanisms involved in this process. In particular, we focus on the stress-induced epigenetic changes mediated by the ATF-2 family of transcription factors.
authors.affiliation: Laboratory of Molecular Genetics, RIKEN Tsukuba Institute, 3-1-1 Koyadai, Tsukuba, Ibaraki 305-0074, Japan.
authors.forename: Ki-Hyeon
authors.initials: KH
authors.lastname: Seong
authors.forename: Toshio
authors.initials: T
authors.lastname: Maekawa
authors.forename: Shunsuke
authors.initials: S
authors.lastname: Ishii
mesh_terms: D051698:Activating Transcription Factor 2 / Q000378:metabolism*; D000818:Animals; D044127:Epigenesis, Genetic; D005823:Genetics / Q000266:history*; D049672:History, 19th Century; D006801:Humans; D013312:Stress, Physiological
chemical_list: D051698:Activating Transcription Factor 2