title: Malignant pheochromocytoma in a pig.
abstract: Endocrine tumors are rarely observed in pigs, and pheochromocytomas have been only punctually described. The current report describes a white and firm, 15-cm in diameter, neoplastic mass located in the adrenal gland with metastasis to regional lymph nodes in a 2.5-year-old sow. The masses had marked desmoplasia that supported a population of polygonal-to-spindle-shaped neoplastic cells arranged into cords and packets within a delicate fibrovascular stroma. Immunohistochemical staining of the tumor was positive for chromogranin and negative for neurofilament protein in adrenal and lymph node masses, which was characteristic of a malignant pheochromocytoma.
authors.affiliation: Departament de Sanitat i Anatomia Animals, Universitat Autònoma Barcelona, Bellaterra, Barcelona, Spain. jorge.martinez.martinez@uab.cat
authors.forename: Jorge
authors.initials: J
authors.lastname: Martínez
authors.forename: Iván
authors.initials: I
authors.lastname: Galindo-Cardiel
authors.forename: Meritxell
authors.initials: M
authors.lastname: Díez-Padrisa
authors.forename: Emilio I
authors.initials: EI
authors.lastname: López-Sabater
authors.forename: Joaquim
authors.initials: J
authors.lastname: Segalés
mesh_terms: D000310:Adrenal Gland Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*; D000311:Adrenal Glands / Q000473:pathology; D000818:Animals; D005260:Female; D010673:Pheochromocytoma / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*; D013552:Swine; D013553:Swine Diseases / Q000175:diagnosis / Q000473:pathology*