title: Evidence-based early clinical detection of emerging diseases in food animals and zoonoses: two cases.
abstract: If diseases of food-producing animals or zoonoses (re-)emerge, early clinical decision making is of major importance. In this particular condition, it is difficult to apply a classic evidence-based veterinary medicine process, because of a lack of available published data. A method based on the partition of field clinical observations (evidences) could be developed as an interesting alternative approach. The classification and regression tree (CART) analysis was used to improve the early clinical detection in two cases of emerging diseases: bovine spongiform encephalopathy (mad cow disease) and bluetongue due to the serotype 8-virus in cattle.
authors.affiliation: Research Unit in Epidemiology and Risk Analysis Applied to Veterinary Sciences (UREAR), Department of Infectious and Parasitic Diseases, Faculty of Veterinary Medicine, University of Liege, B42, Boulevard de Colonster 20, B42, B-4000 Liege, Belgium. Claude.Saegerman@ulg.ac.be
authors.forename: Claude
authors.initials: C
authors.lastname: Saegerman
authors.forename: Marie-France
authors.initials: MF
authors.lastname: Humblet
authors.forename: Sarah Rebecca
authors.initials: SR
authors.lastname: Porter
authors.forename: Gina
authors.initials: G
authors.lastname: Zanella
authors.forename: Ludovic
authors.initials: L
authors.lastname: Martinelle
mesh_terms: D000818:Animals; D001819:Bluetongue / Q000175:diagnosis* / Q000453:epidemiology / Q000635:transmission; D002417:Cattle; D002418:Cattle Diseases / Q000175:diagnosis* / Q000453:epidemiology / Q000635:transmission; D021821:Communicable Diseases, Emerging / Q000175:diagnosis / Q000453:epidemiology / Q000635:transmission / Q000662:veterinary*; D042241:Early Diagnosis; D016643:Encephalopathy, Bovine Spongiform / Q000175:diagnosis* / Q000453:epidemiology / Q000635:transmission; D019317:Evidence-Based Medicine; D006801:Humans; D015047:Zoonoses