title: Medicinal benefits of marine invertebrates: sources for discovering natural drug candidates.
abstract: Marine invertebrates are one of the major groups of organisms, which could be diversified under the major taxonomic groups of Porifera, Cnidaria, Mollusca, Arthropoda, Echinodermata, and many other minor phyla. To date, range of medicinal benefits and a significant number of marine natural products (MNPs) have been discovered from marine invertebrates. Seafood diet from edible marine invertebrates such as mollusks and crustaceans has been linked with various medicinal benefits to improve human health. Among marine invertebrates, spongers from phylum Porifera is the most dominant group responsible for discovering large number of MNPs, which have been used as template to develop therapeutic drugs. MNPs isolated from invertebrates have shown wide range of therapeutic properties including antimicrobial, antioxidant, antihypertensive, anticoagulant, anticancer, anti-inflammatory, wound healing and immune modulator, and other medicinal effects. Therefore, marine invertebrates are rich sources of chemical diversity and health benefits for developing drug candidates, cosmetics, nutritional supplements, and molecular probes that can be supported to increase the healthy life span of human.
authors.affiliation: College of Veterinary Medicine, Chungnam National University, Daejeon, Republic of Korea. mahanama@cnu.ac.kr
authors.forename: Mahanama
authors.initials: M
authors.lastname: De Zoysa
mesh_terms: D000818:Animals; D059001:Aquatic Organisms / Q000254:growth & development / Q000378:metabolism*; D001181:Arthropods / Q000254:growth & development / Q000378:metabolism; D003063:Cnidaria / Q000254:growth & development / Q000378:metabolism; D055808:Drug Discovery; D004447:Echinodermata / Q000254:growth & development / Q000378:metabolism; D055951:Functional Food / Q000032:analysis; D006801:Humans; D007448:Invertebrates / Q000254:growth & development / Q000378:metabolism*; D008387:Marine Toxins / Q000633:toxicity; D008974:Mollusca / Q000254:growth & development / Q000378:metabolism; D011161:Porifera / Q000254:growth & development / Q000378:metabolism; D012758:Shellfish / Q000032:analysis
chemical_list: D008387:Marine Toxins