title: Treatment of congenital tracheal stenosis by balloon-expandable metallic stents in paediatric intensive care unit.
abstract: The aim of this study was to evaluate the use of balloon-expandable metallic stents in the treatment of children with congenital tracheal stenosis in whom conventional therapy has failed. From 2010 to 2011, balloon-expandable metallic stents were implanted into the trachea of eight infants aged 2-20 months in the paediatric intensive care unit. The infants had severe airway obstruction caused by congenital tracheal stenosis. Tracheal stents were placed after intraluminal balloon dilatation of the tracheal stenosis, inserted with balloon catheters and implanted into the desired position bronchoscopically. The stents were 12 to 29 mm long and 4 mm in diameter. Seven children were relieved of airway obstruction after this procedure. However, a child died due to severe sepsis after the placement of bronchial stents. No granulation tissue developed over the stents in any of the children. Stents have been in place for 1-6 months after insertion without any other complication. Balloon-expandable metallic stents are effective in relieving airway obstruction by congenital tracheal stenosis in children. This technique may provide an important remedy for congenital tracheal stenosis in children.
authors.affiliation: Centre of Children's Advanced Disease,  Bayi Children's Hospital Affiliated to General Hospital of Beijing Military Commond, Beijing,  China.
authors.forename: Xuan
authors.initials: X
authors.lastname: Xu
authors.forename: Dandan
authors.initials: D
authors.lastname: Li
authors.forename: Shuyu
authors.initials: S
authors.lastname: Zhao
authors.forename: Xicheng
authors.initials: X
authors.lastname: Liu
authors.forename: Zhichun
authors.initials: Z
authors.lastname: Feng
authors.forename: Hui
authors.initials: H
authors.lastname: Ding
mesh_terms: D000402:Airway Obstruction / Q000175:diagnosis / Q000209:etiology / Q000401:mortality / Q000628:therapy*; D001999:Bronchoscopy; D002404:Catheterization / Q000009:adverse effects / Q000295:instrumentation* / Q000401:mortality; D002681:China; D054855:Drug-Eluting Stents; D006801:Humans; D007223:Infant; D015278:Intensive Care Units, Pediatric; D008670:Metals; D011474:Prosthesis Design; D020123:Sirolimus / Q000008:administration & dosage; D013997:Time Factors; D014135:Tracheal Stenosis / Q000151:congenital / Q000175:diagnosis / Q000401:mortality / Q000628:therapy*; D016896:Treatment Outcome
chemical_list: D008670:Metals; D020123:Sirolimus