title: In vivo comparison of Fourier-domain optical coherence tomography and intravascular ultrasonography.
abstract: BACKGROUND
  We sought to evaluate the findings of Fourier-domain optical coherence tomography (FD-OCT) and intravascular ultrasonography (IVUS) used for the in vivo assessment of coronary lesions.
  
  
  METHODS
  We identified 19 lesions in 15 patients undergoing percutaneous coronary intervention that were assessed by both FD-OCT and IVUS and compared the lumen area and maximum/minimum lumen diameter at the site of maximum stenosis and the proximal and distal reference cross-sections.
  
  
  RESULTS
  At the site of maximum stenosis, excellent correlation was found between FD-OCT and IVUS measurements: minimum lumen area (3.80 ± 2.36 mm² and 4.60 ± 2.13 mm², respectively; P=.002; Spearman's ρ = 0.94), maximum lumen diameter (2.30 ± 0.79 mm and 2.54 ± 0.60 mm, respectively; P=.005; Spearman's ρ = 0.93), and minimum lumen diameter (1.89 ± 0.69 mm and 2.24 ± 0.54 mm, respectively; P=.0001; Spearman's ρ = 0.90). Weaker correlations were found between FD-OCT and IVUS measurements of the proximal reference lumen area (4.74 ± 1.86 mm² and 5.16 ± 2.10 mm², respectively; P=.33; Spearman's ρ = 0.76) and distal reference lumen area (5.14 ± 1.60 mm² and 5.47 ± 2.45 mm², respectively; P=.144; Spearman's ρ = 0.72).
  
  
  CONCLUSIONS
  Excellent correlation was found in FD-OCT and IVUS luminal measurements at the site of maximum coronary stenosis with weaker correlation at the proximal and distal reference cross-sections. FD-OCT minimum lumen area measurements were smaller than the IVUS measurements.
authors.affiliation: UT Southwestern and VA North Texas Healthcare System, Dallas, Texas, USA.
authors.forename: Sathyadeepak
authors.initials: S
authors.lastname: Ramesh
authors.forename: Aristotelis
authors.initials: A
authors.lastname: Papayannis
authors.forename: Abdul-rahman
authors.initials: AR
authors.lastname: Abdel-karim
authors.forename: Subhash
authors.initials: S
authors.lastname: Banerjee
authors.forename: Emmanouil
authors.initials: E
authors.lastname: Brilakis
mesh_terms: D000368:Aged; D015906:Angioplasty, Balloon, Coronary; D017023:Coronary Angiography; D023921:Coronary Stenosis / Q000000981:diagnostic imaging* / Q000473:pathology* / Q000628:therapy; D003331:Coronary Vessels / Q000000981:diagnostic imaging / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D041623:Tomography, Optical Coherence / Q000379:methods*; D018084:Ultrasonography, Interventional / Q000379:methods*