title: Characteristics of peripheral nerve regeneration following a second nerve injury and repair.
abstract: During the process of peripheral nerve regeneration, a single neuron can regenerate and maintain more than one collateral in a regenerative distal stump. Furthermore, some of the new shoots can mature gradually through remyelination and grow into the remote target organ to play a physiological function. Our study found that when neonatal nerve fibers are subjected to a second injury, the regenerative distal stump can regenerate and maintain more than one collateral in the second regenerative distal stump. The neonatal nerve contributed to the functional recovery of the nerve, but the restoration of nerve function was not complete.
authors.affiliation: Peking University People's Hospital, Beijing, China.
authors.forename: Yanhua
authors.initials: Y
authors.lastname: Wang
authors.forename: Peixun
authors.initials: P
authors.lastname: Zhang
authors.forename: Xiaofeng
authors.initials: X
authors.lastname: Yin
authors.forename: Jianping
authors.initials: J
authors.lastname: Peng
authors.forename: Yuhui
authors.initials: Y
authors.lastname: Kou
authors.forename: Zhenjun
authors.initials: Z
authors.lastname: Zhang
authors.forename: Dianying
authors.initials: D
authors.lastname: Zhang
authors.forename: Baoguo
authors.initials: B
authors.lastname: Jiang
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D008297:Male; D009132:Muscles / Q000294:innervation / Q000473:pathology; D009186:Myelin Sheath / Q000502:physiology; D009412:Nerve Fibers / Q000473:pathology; D009416:Nerve Regeneration / Q000502:physiology*; D059348:Peripheral Nerve Injuries / Q000473:pathology / Q000503:physiopathology*; D010543:Peroneal Nerve / Q000293:injuries* / Q000473:pathology / Q000503:physiopathology*; D051381:Rats; D017207:Rats, Sprague-Dawley; D013979:Tibial Nerve / Q000293:injuries* / Q000473:pathology / Q000503:physiopathology*