title: Gorham-Stout disease affecting both hands: stabilisation during biphosphonate treatment.
abstract: The Gorham-Stout syndrome is a rare condition in which spontaneous, progressive resorption of bone occurs. The aetiology is poorly understood. We report a patient with osteolysis of the metacarpal bones in both hands due to an increased number of stimulated osteoclasts. This suggests that early potent antiresorptive therapy with bisphosphonates may prevent local progressive osteolysis.
authors.affiliation: Hospital de Los Valles, Av. Interoceanica Km. 12 1/2 y Av. Florencia, Cumbaya, PBX 6000 900/2977 900 Quito Ecuador.
authors.forename: Santiago
authors.initials: S
authors.lastname: Silva