title: Surface assisted laser desorption ionization-mass spectrometry (SALDI-MS) for analysis of polyester degradation products.
abstract: Novel surface assisted laser desorption ionization-mass spectrometry (SALDI-MS) method was developed for rapid analysis of low molecular mass polyesters and their degradation products by laser desorption ionization-mass spectrometry. Three polycaprolactone materials were analyzed by the developed method before and after hydrolytic degradation. The signal-to-noise values obtained by SALDI-MS were 20-100 times higher compared with the ones obtained by using traditional MALDI-MS matrices. A clean background at low mass range and higher resolution was obtained by SALDI-MS. Different nanoparticle, cationizing agent, and solvent combinations were evaluated. Halloysite nanoclay and magnesium hydroxide showed the best potential as SALDI surfaces. The SALDI-MS spectrum of the polyester hydrolysis products was verified by ESI-MS. The developed SALDI-MS method possesses several advantages over existing methods for similar analyses.
authors.affiliation: Department of Fibre and Polymer Technology, School of Chemical Science and Engineering, KTH Royal Institute of Technology, Stockholm, Sweden.
authors.forename: Nina
authors.initials: N
authors.lastname: Aminlashgari
authors.forename: Minna
authors.initials: M
authors.lastname: Hakkarainen
mesh_terms: D000538:Aluminum Silicates / Q000737:chemistry; D000077215:Clay; D007477:Ions / Q000737:chemistry; D008276:Magnesium Hydroxide / Q000737:chemistry; D053758:Nanoparticles / Q000737:chemistry; D011091:Polyesters / Q000032:analysis / Q000737:chemistry*; D015203:Reproducibility of Results; D059629:Signal-To-Noise Ratio; D021241:Spectrometry, Mass, Electrospray Ionization; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / Q000379:methods*
chemical_list: D000538:Aluminum Silicates; D007477:Ions; D011091:Polyesters; C016240:polycaprolactone; D008276:Magnesium Hydroxide; D000077215:Clay