title: A large outbreak of enteritis in goat flocks in Marmara, Turkey, by G8P[1] group A rotaviruses.
abstract: Group A rotaviruses are regarded as major enteric pathogens of large ruminants, while their impact on the health of small ruminants is not well documented. We report the detection of group A rotavirus from a large outbreak of enteritis that occurred in two goat flocks in the town of Kırklareli, Marmara Region, Turkey, in 2007. The disease was observed in young kids, with high morbidity and mortality rates, but not in adult animals. Rotavirus antigen was detected in the stools of the examined animals, and rotaviruses were isolated in MA104 cells. Upon sequencing of the VP4, VP6, VP7 and NSP4 genes, the strain (RVA/goat-tc/TUR/Kirklareli/2007/G8P[1]) was characterized as G8P[1], with E2 NSP4 and VP6 I2 genotype. These findings indicate that group A rotavirus should be included in the diagnostic algorithms for enteric disease in small ruminants.
authors.affiliation: Virology Department, Faculty of Veterinary Medicine, Ankara University, Diskapi, Turkey. falkan@ankara.edu.tr
authors.forename: Feray
authors.initials: F
authors.lastname: Alkan
authors.forename: Veli
authors.initials: V
authors.lastname: Gulyaz
authors.forename: M
authors.initials: M
authors.lastname: Ozkan Timurkan
authors.forename: Selma
authors.initials: S
authors.lastname: Iyisan
authors.forename: Selma
authors.initials: S
authors.lastname: Ozdemir
authors.forename: Nesrin
authors.initials: N
authors.lastname: Turan
authors.forename: Canio
authors.initials: C
authors.lastname: Buonavoglia
authors.forename: Vito
authors.initials: V
authors.lastname: Martella
mesh_terms: D000818:Animals; D004196:Disease Outbreaks; D004751:Enteritis / Q000453:epidemiology / Q000662:veterinary* / Q000821:virology*; D015511:Goat Diseases / Q000453:epidemiology / Q000821:virology*; D006041:Goats; D006801:Humans; D008969:Molecular Sequence Data; D010802:Phylogeny; D012401:Rotavirus / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D012400:Rotavirus Infections / Q000453:epidemiology / Q000662:veterinary* / Q000821:virology*; D014421:Turkey / Q000453:epidemiology