title: Role of biomarkers in the diagnosis and management of cardio-renal syndromes.
abstract: The complex interaction between heart and kidney disease has been increasingly recognized over the recent years. Pathologies within these two organs frequently coexist and, due to organ cross-talk, dysfunction in one often leads to problems in the other. The classification of the various forms of cardio-renal syndrome has made these interactions clearer. To aid in the diagnosis, management and prognosis of these conditions, many novel cardiac and renal biomarkers have emerged to supplement traditional markers which have limited specificity and sensitivity. In this review we will summarize the literature on novel renal behind these and other biomarkers and discuss their potential relevance to the clinical scenarios of cardio-renal syndrome.
authors.affiliation: Department of Nephrology Dialysis and Transplantation, San Bortolo Hospital, Vicenza, Italy. dinnacruzmd@yahoo.com
authors.forename: Dinna N
authors.initials: DN
authors.lastname: Cruz
authors.forename: Arrash
authors.initials: A
authors.lastname: Fard
authors.forename: Anna
authors.initials: A
authors.lastname: Clementi
authors.forename: Claudio
authors.initials: C
authors.lastname: Ronco
authors.forename: Alan
authors.initials: A
authors.lastname: Maisel
mesh_terms: D058186:Acute Kidney Injury / Q000097:blood* / Q000209:etiology; D015415:Biomarkers / Q000097:blood*; D059347:Cardio-Renal Syndrome / Q000097:blood / Q000175:diagnosis / Q000628:therapy; D006333:Heart Failure / Q000097:blood*; D006801:Humans; D011379:Prognosis
chemical_list: D015415:Biomarkers