title: [Organization, function and genetic controlling of synaptonemal complex].
abstract: The synaptonemal complex (SC) is a super protein lattice that connects paired homologous chromosomes in most meiotic systems. This special organization is related to the meiosis processes such as homologous chromosomes pairing, synapsis, recombination, segregation, etc. Flaws of it would lead the meiocytes to apoptosis, which contributes to sterility. In recent years, the study of this complex has been a hotspot in meiosis research, but little was known about its exact mechanism. This review summarized the organization, function, and genetics of this complex with recent advances. Prospects of its further study were also briefly discussed..
authors.affiliation: China Agricultural University, Beijing, China. xie-wen-jun@163.com
authors.forename: Wen-Jun
authors.initials: WJ
authors.lastname: Xie
authors.forename: Dian-Yi
authors.initials: DY
authors.lastname: Shi
authors.forename: Ze-Xi
authors.initials: ZX
authors.lastname: Cai
authors.forename: Xiao-Yang
authors.initials: XY
authors.lastname: Chen
authors.forename: Wei-Wei
authors.initials: WW
authors.lastname: Jin
mesh_terms: D000818:Animals; D017209:Apoptosis; D006801:Humans; D008540:Meiosis; D011995:Recombination, Genetic; D013573:Synaptonemal Complex / Q000235:genetics / Q000502:physiology*