title: [Body mass changes during pregnancy and concentration of insulin and neuropeptide Y in women with regard to the BMI].
abstract: BACKGROUND
  Obesity poses a serious problem to human population as it increases the risk of diabetes, hypertension, metabolic syndrome. In pregnancy obesity increases the frequency of its complications.
  
  
  OBJECTIVE
  The main aim of the study was to estimate the increase of body mass and insulin and neuropeptide Y concentrations in pregnant women.
  
  
  METHODS
  The changes of body mass and BMI in women before pregnancy and before delivery and the concentrations of insulin and neuropeptide Y in blood were estimated.
  
  
  RESULTS
  The increase of body mass and BMI during the pregnancy period was higher in the group with high body mass and I stage obesity and increase of insulin concentration depended on increase of the body mass. Higher concentration of NPY was found in the group of women with normal body mass and obese if compared to stages II and III of obesity No correlation between insulin increase and concentration of NPY was found.
  
  
  CONCLUSIONS
  In most pregnant women body mass gain is excessive and leads to obesity of different stages. Insulin concentration increases as BMI increases. Neuropeptide Y concentration in the obese women group was lower than in the normal weight group.
authors.affiliation: Klinika Patologii Ciazy Uniwersytetu Medycznego w Łodzi, Polska.
authors.forename: Dorota
authors.initials: D
authors.lastname: Estemberg
authors.forename: Anita
authors.initials: A
authors.lastname: Sikora-Szubert
authors.forename: Urszula
authors.initials: U
authors.lastname: Kowalska-Koprek
authors.forename: Marlena
authors.initials: M
authors.lastname: Berner-Trabska
authors.forename: Maria
authors.initials: M
authors.lastname: Brzozowska
authors.forename: Jacek
authors.initials: J
authors.lastname: Pasiński
authors.forename: Arkadiusz
authors.initials: A
authors.lastname: Swierczewski
authors.forename: Agata
authors.initials: A
authors.lastname: Karowicz-Bilińska
mesh_terms: D000328:Adult; D001824:Body Constitution; D015992:Body Mass Index; D005260:Female; D006801:Humans; D007328:Insulin / Q000097:blood*; D009478:Neuropeptide Y / Q000097:blood*; D009765:Obesity / Q000097:blood*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000097:blood* / Q000517:prevention & control; D011264:Pregnancy Trimesters; D018566:Pregnancy, High-Risk / Q000097:blood; D011295:Prenatal Care / Q000379:methods; D012016:Reference Values; D012307:Risk Factors; D016387:Women's Health; D055815:Young Adult
chemical_list: D007328:Insulin; D009478:Neuropeptide Y