title: Unusual trocar site metastasis in a uterine leiomyosarcoma after laparoscopic hysterectomy.
abstract: With widespread use of laparoscopy in patients with gynecologic malignancy, occasionally port-site metastasis is an item of concern. Herein we report a case of leiomyosarcoma of the uterus that metastasized to an accessory port after laparoscopic-assisted vaginal hysterectomy. A 46-year-old woman with a preoperative diagnosis of leiomyoma underwent laparoscopic-assisted vaginal hysterectomy. Final histopathologic findings revealed leiomyosarcoma. A postoperative abdominopelvic computed tomography scan demonstrated no evidence of metastatic tumor. The patient received 6 courses of combined chemotherapy consisting of cisplatin and ifosfamide. Follow-up computed tomography was performed because of pelvic pain at 4 months after treatment and revealed a recurrent pelvic tumor and a metastatic mass at previous right trocar site. At debulking surgery, a pelvic mass measuring 10 cm was observed, and a subcutaneous nodule measuring 4 cm was noted at the site of the right accessory port, with intact underlying peritoneum. After complete removal of both tumors, concurrent chemoradiation consisting of external radiotherapy and cisplatin was administered. Six months after the second surgery, a pelvic mass measuring 15 cm was observed. A second debulking surgical procedure was performed. However, the patient died of the disease 6 months after the second recurrence.
authors.affiliation: Department of Obstetrics and Gynecology, Juntendo University Nerima Hospital, Tokyo, Japan.
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Ota
authors.forename: Kuan-Gen
authors.initials: KG
authors.lastname: Huang
authors.forename: Renee Vina G
authors.initials: RV
authors.lastname: Sicam
authors.forename: Shir-Hwa
authors.initials: SH
authors.lastname: Ueng
authors.forename: Chyi-Long
authors.initials: CL
authors.lastname: Lee
mesh_terms: D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007045:Hysterectomy, Vaginal / Q000009:adverse effects* / Q000295:instrumentation / Q000379:methods; D010535:Laparoscopy / Q000009:adverse effects* / Q000295:instrumentation; D007890:Leiomyosarcoma / Q000175:diagnosis / Q000556:secondary* / Q000601:surgery; D008875:Middle Aged; D010386:Pelvic Neoplasms / Q000175:diagnosis / Q000556:secondary* / Q000601:surgery; D014594:Uterine Neoplasms / Q000473:pathology* / Q000601:surgery