title: Effectiveness of ultraporous β-tricalcium phosphate (vitoss) as bone graft substitute for cavitary defects in benign and low-grade malignant bone tumors.
abstract: We retrospectively evaluated healing with ultraporous β-tricalcium phosphate (β-TCP [Vitoss; Orthovida, Malvern, Pennsylvania]) bone graft in patients who underwent surgical excision or curettage of benign bone lesions subsequently filled with bone void filler. Twentynine patients were treated with curettage and ultraporous β-TCP morsels. Radiologic defect size at initial postoperative presentation and subsequent visits (minimum follow-up, 6 months) was evaluated. Results suggested that an ultraporous β-TCP synthetic bone graft is effective in managing bone voids. The vast majority of patients who undergo curettage for benign bone lesions can expect to have complete or near complete healing of these defects within 6 months of their surgical procedure with use of ultraporous β-TCP morsels.
authors.affiliation: Department of Orthopaedics, Ohio State University Medical Center, Columbus, Ohio 43210-1280, USA.
authors.forename: Corey
authors.initials: C
authors.lastname: Van Hoff
authors.forename: Julie Balch
authors.initials: JB
authors.lastname: Samora
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Griesser
authors.forename: Martha K
authors.initials: MK
authors.lastname: Crist
authors.forename: Thomas J
authors.initials: TJ
authors.lastname: Scharschmidt
authors.forename: Joel L
authors.initials: JL
authors.lastname: Mayerson
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001672:Biocompatible Materials / Q000627:therapeutic use*; D001859:Bone Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D018786:Bone Substitutes / Q000627:therapeutic use*; D016025:Bone Transplantation / Q000295:instrumentation / Q000379:methods*; D002130:Calcium Phosphates / Q000627:therapeutic use*; D002648:Child; D015331:Cohort Studies; D005260:Female; D006801:Humans; D035002:Lower Extremity / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D011859:Radiography; D012189:Retrospective Studies; D016896:Treatment Outcome; D034941:Upper Extremity / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D055815:Young Adult
chemical_list: D001672:Biocompatible Materials; D018786:Bone Substitutes; D002130:Calcium Phosphates; C485817:beta-tricalcium phosphate