title: [De novo sarcoidosis after kidney transplantation].
abstract: METHODS
  A 39-year-old man complained of unspecific chest pains four years after kidney transplantation.
  
  
  METHODS
  Laboratory tests revealed a slow increase of retentions values; the value of soluble IL-2 receptor was slightly elevated. Computed tomography of the chest confirmed mediastinal and bilateral hilar masses. The broncho-alveolar lavage (BAL) showed a marked increase of the CD4/CD8 T-lymphocyte ratio and the aspiration cytology of these lymphadenopathies revealed the cytopathological characteristics of sarcoidosis.
  
  
  METHODS
  An asymptomatic stage I sarcoidosis was diagnosed, and the immunosuppressive treatment with cyclosporine, mycophenolatmofetil and prednisone was retained. The patient has remained asymptomatic for now six months.
  
  
  CONCLUSIONS
  When bilateral hilar / mediastinal lymphadenopathies occur after organ transplantation with immunosuppression de novo sarcoidosis should be taken into account.
authors.affiliation: Klinik II für Innere Medizin, Uniklinik Köln.
authors.forename: T
authors.initials: T
authors.lastname: Kisner
authors.forename: R
authors.initials: R
authors.lastname: Pfister
authors.forename: M
authors.initials: M
authors.lastname: Engels
authors.forename: T
authors.initials: T
authors.lastname: Benzing
authors.forename: G
authors.initials: G
authors.lastname: Michels
mesh_terms: D000328:Adult; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D016030:Kidney Transplantation / Q000009:adverse effects*; D008297:Male; D017565:Sarcoidosis, Pulmonary / Q000188:drug therapy* / Q000209:etiology* / Q000517:prevention & control; D016896:Treatment Outcome
chemical_list: D007166:Immunosuppressive Agents