title: Intraflagellar transport--the "new motility" 20 years later.
abstract: Intraflagellar transport is the rapid, bidirectional movement of protein complexes along the length of most eukaryotic cilia and flagella. Discovery of this intracellular process in Chlamydomonas reinhardtii 20 years ago led to a rapid discovery of cellular mechanisms that underlie a large number of human ciliopathies. Described herein are the events that led to this discovery.
authors.affiliation: Departments of Biology and Cell Biology, University of Virginia, Charlottesville, VA 22904, USA. kkoz@virginia.edu
authors.forename: Keith G
authors.initials: KG
authors.lastname: Kozminski
mesh_terms: D016825:Chlamydomonas reinhardtii / Q000378:metabolism*; D002923:Cilia / Q000378:metabolism*; D005407:Flagella / Q000378:metabolism*; D049673:History, 20th Century; D049674:History, 21st Century; D010940:Plant Proteins / Q000266:history* / Q000378:metabolism; D021381:Protein Transport
chemical_list: D010940:Plant Proteins