title: Dexamethasone treatment has no effect on the formation of pneumococcal antibodies during community-acquired pneumonia.
abstract: In this study, the effect of dexamethasone on the formation of pneumococcal antibodies during community-acquired pneumonia (CAP) was investigated. No differences between CAP patients receiving dexamethasone as additional therapy and patients receiving a placebo were found with respect to immune response rates and mean baseline and convalescent-phase antibody concentrations.
authors.affiliation: Department of Medical Microbiology & Immunology, St. Antonius Hospital, Nieuwegein, the Netherlands. s.van.mens@antoniusziekenhuis.nl
authors.forename: Suzan P
authors.initials: SP
authors.lastname: van Mens
authors.forename: Sabine C A
authors.initials: SC
authors.lastname: Meijvis
authors.forename: Jan C
authors.initials: JC
authors.lastname: Grutters
authors.forename: Bart J M
authors.initials: BJ
authors.lastname: Vlaminckx
authors.forename: Willem J W
authors.initials: WJ
authors.lastname: Bos
authors.forename: Ger T
authors.initials: GT
authors.lastname: Rijkers
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000907:Antibodies, Bacterial / Q000097:blood*; D000970:Antineoplastic Agents / Q000008:administration & dosage*; D017714:Community-Acquired Infections / Q000276:immunology*; D003907:Dexamethasone / Q000008:administration & dosage*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010919:Placebos / Q000008:administration & dosage; D011018:Pneumonia, Pneumococcal / Q000276:immunology*
chemical_list: D000907:Antibodies, Bacterial; D000970:Antineoplastic Agents; D010919:Placebos; D003907:Dexamethasone