title: Dorsal root ganglion - a potential new therapeutic target for neuropathic pain.
abstract: A regional approach can protect our patients from often unacceptable adverse effects produced by systematically applied drugs. Regional therapeutic approaches, as well as interventions at the level of the peripheral nervous system and particularly the dorsal root ganglion (DRG), represent an alternative to the systemic application of therapeutic agents. This article provides an overview of DRG anatomical peculiarities, explains why the DRG is an important therapeutic target, and how animal models of targeted drug delivery can help us in the translation of basic research into clinical practice.
authors.affiliation: Department of Anatomy, Histology, and Embryology, University of Split Medical School, Soltanska 2, 21000 Split, Croatia.
authors.forename: Damir
authors.initials: D
authors.lastname: Sapunar
authors.forename: Sandra
authors.initials: S
authors.lastname: Kostic
authors.forename: Adriana
authors.initials: A
authors.lastname: Banozic
authors.forename: Livia
authors.initials: L
authors.lastname: Puljak