title: AssessMent of ProphylAxis for VenouS ThromboembolIsm in hospitalized patients: the MASIH study.
abstract: BACKGROUND
  Venous thromboembolism (VTE) accounts for several cases of in-hospital mortality (over 100 000 deaths annually in the West). Despite the existence of effective prophylaxis guidelines for at-risk patients, the guidelines adherence is missing.
  
  
  METHODS
  We evaluated the thromboprophylaxis reception and appropriateness based on the eighth edition of the American College of Chest Physicians (ACCP) guidelines on VTE prophylaxis, among hospitalized patients of a World Health Organization (WHO)-collaborating teaching hospital in a 3-month period.
  
  
  RESULTS
  From the 904 evaluated cases, 481 entered the study. Appropriate decision on whether to prophylaxe or not, was made in 305 (63.40%), however, complete appropriateness (considering correct regimen type, dosing, and duration) was seen only in 229 patients (47.60%). The ACCP risk for VTE was the strongest predictor of thromboprophylaxis prescription (odds ratio [OR]: 2.62, 95% confidence interval [CI]: 1.35-5.05).
  
  
  CONCLUSIONS
  Our thromboprophylaxis results were comparable to that of Western countries. Improved thromboprophylaxis appropriateness, which requires improving the physicians' thromboprophylaxis awareness and knowledge, could reduce the rate of in-hospital VTE and translate into better patient care.
authors.affiliation: Tobacco Prevention and Control Research Center.
authors.forename: Babak
authors.initials: B
authors.lastname: Sharif-Kashani
authors.forename: Payman
authors.initials: P
authors.lastname: Shahabi
authors.forename: Sasan
authors.initials: S
authors.lastname: Raeissi
authors.forename: Neda
authors.initials: N
authors.lastname: Behzadnia
authors.forename: Alireza
authors.initials: A
authors.lastname: Shoaraka
authors.forename: Mahan
authors.initials: M
authors.lastname: Shahrivari
authors.forename: Leila
authors.initials: L
authors.lastname: Saliminejad
authors.forename: Saviz
authors.initials: S
authors.lastname: Pozhhan
authors.forename: Mohammad-Reza
authors.initials: MR
authors.lastname: Hashemian
authors.forename: Mohammad-Reza
authors.initials: MR
authors.lastname: Masjedi
authors.forename: Behnood
authors.initials: B
authors.lastname: Bikdeli
mesh_terms: D016022:Case-Control Studies; D005260:Female; D017052:Hospital Mortality; D006760:Hospitalization; D006801:Humans; D008297:Male; D008875:Middle Aged; D054556:Venous Thromboembolism / Q000401:mortality* / Q000517:prevention & control*