title: [Interest of flexible videocystoscopy in blue light (+Hexvix(®)) in consultation for the diagnosis of vesical tumor].
abstract: OBJECTIVE
  Estimate the feasibility and the results of the realization in consultation of a flexible videocystoscopy in blue light preceded by an instillation of Hexvix(®) (GE Healthcare) for the initial diagnosis or the surveillance of vesicals tumors (VT). The objective of this study was to compare the number of hurts seen in white light and in blue light, and to estimate in which percentage of case the use of the Hexvix(®) in consultation modified the care.
  
  
  METHODS
  Thirty consecutive patients (26 men and four women) were estimated prospectively by vesical videofibroscopy in blue light (Wolf's PD videofibroscope) realized 1 hour after an endovesical instillation of Hexvix(®). All the examinations were realized in external consultation under local anesthetic by xylocaine gel: 23 (76.6%) patients within the framework of a surveillance of VT and seven (23.4%) for the diagnosis of a hematuria with normal echography. When a suspect hurt or a VT was discovered, the patients benefited from an endoscopic resection under anesthesia with new cystoscopy in blue light.
  
  
  RESULTS
  Suspect hurts were revealed in 10 out of 30 patients, five in white and blue light, five in blue light only. Among the five only visible hurts in blue light, three were urothelial tumors (any pTa of bottom-rank, less of 5 mm) and two non-specific hurts. No CIS's hurt was revealed during this study. The fibroscopy in blue light allowed to diagnose invisible hurts in white light in three patients (10%) and has modified the care of five patients (16.7%). The duration of the cystoscopy was on average of 9.5 minutes. The tolerance of the examination was good and no complication arose.
  
  
  CONCLUSIONS
  The use of the flexible videocystoscopy in blue light +Hexvix(®) has allowed to improve the rate of detection of VT. Except CIS's hurts, this improvement was bound to the diagnosis of little aggressive small-sized VT. The indications must be specified by studies of bigger scale and a medical economic evaluation.
authors.affiliation: Service d'urologie, CHU de Nîmes, place du Pr-Debré, 30029 Nîmes cedex 9, France. j.bertrand06@laposte.net
authors.forename: J
authors.initials: J
authors.lastname: Bertrand
authors.forename: L
authors.initials: L
authors.lastname: Soustelle
authors.forename: P
authors.initials: P
authors.lastname: Grès
authors.forename: L
authors.initials: L
authors.lastname: Wagner
authors.forename: C
authors.initials: C
authors.lastname: Muyshondt
authors.forename: M
authors.initials: M
authors.lastname: Boukaram
authors.forename: K
authors.initials: K
authors.lastname: Ben Naoum
authors.forename: P
authors.initials: P
authors.lastname: Costa
authors.forename: S
authors.initials: S
authors.lastname: Droupy
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000622:Aminolevulinic Acid / Q000031:analogs & derivatives*; D003558:Cystoscopy / Q000379:methods*; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D001749:Urinary Bladder Neoplasms / Q000473:pathology*; D014741:Video Recording
chemical_list: D000622:Aminolevulinic Acid; C419924:5-aminolevulinic acid hexyl ester