title: The incidence and outcome of severe brain trauma - Design and first results of an epidemiological study in an urban area.
abstract: Epidemiological data on the incidence, the prehospital and hospital care and the outcome of traumatic brain injury in Germany are scarce. It is therefore difficult to estimate the importance of this injury with respect to magnitude as well as effectiveness and efficiency of therapeutic concepts. We therefore planned a study that was supposed to provide population based epidemiological data in the field of severe brain trauma from the site of the accident until discharge from hospital.All 90.000 prehospital emergencies that were cared for by emergency physicians in Cologne from January 1990 until December 1996 were screened for identification of severe brain trauma. Their clinical course was reviewed using standard records and patients were included if they had their accident within the city of Cologne and fullfilled the final inclusion criteria of GCS ≤ 8 or AISHead ≥ 3. 650 eligible patients were identified of whom 530 had complete datasets (follow-up 80 %). Univariate statistical analysis was performed for all relevant variables. The main study endpoints were incidence and outcome of severe brain trauma.The annual incidence of severe brain trauma in Cologne (1 mio. inhabitants) was 93. The average age was 39 years and 71 % of the patients were male. The average prehospital GCS was 6.8, the average prehospital Trauma Score was 8.3 points. 49 % of the study population suffered from multiple injuries. The overall mortality rate was 46,6 %. 60 % of deaths occurred within the prehospital setting.The incidence of severe brain trauma in Cologne in this study was significantly lower compared to what could be expected from the literature. The overall mortality was high, especially the high prehospital death rate is striking.
authors.affiliation: II. Department of Surgery, University of Cologne.
authors.forename: B
authors.initials: B
authors.lastname: Bouillon
authors.forename: M
authors.initials: M
authors.lastname: Raum
authors.forename: H
authors.initials: H
authors.lastname: Fach
authors.forename: B
authors.initials: B
authors.lastname: Buchheister
authors.forename: R
authors.initials: R
authors.lastname: Lefering
authors.forename: J
authors.initials: J
authors.lastname: Menzel
authors.forename: N
authors.initials: N
authors.lastname: Klug