title: A mitochondria-localized two-photon fluorescent probe for ratiometric imaging of hydrogen peroxide in live tissue.
abstract: We report a two-photon fluorescent probe (SHP-Mito) which can ratiometrically detect mitochondrial H(2)O(2) in live cells and intact tissues at >100 μm depth through the use of two-photon microscopy.
authors.affiliation: Division of Energy Systems Research and Molecular Science & Technology Research Center, Ajou University, Suwon, 443-749, Korea.
authors.forename: Goutam
authors.initials: G
authors.lastname: Masanta
authors.forename: Cheol Ho
authors.initials: CH
authors.lastname: Heo
authors.forename: Chang Su
authors.initials: CS
authors.lastname: Lim
authors.forename: Sung Keun
authors.initials: SK
authors.lastname: Bae
authors.forename: Bong Rae
authors.initials: BR
authors.lastname: Cho
authors.forename: Hwan Myung
authors.initials: HM
authors.lastname: Kim
mesh_terms: D000818:Animals; D005456:Fluorescent Dyes; D006624:Hippocampus; D006861:Hydrogen Peroxide / Q000032:analysis*; D008856:Microscopy, Fluorescence; D008928:Mitochondria; D017785:Photons; D051381:Rats
chemical_list: D005456:Fluorescent Dyes; D006861:Hydrogen Peroxide