title: [Case of metastatic malignant melanoma detected by multifocal cerebral hemorrhage].
abstract: We encountered a case of intracranial metastatic malignant melanoma which caused repeated multiple hemorrhage. Intracranial metastatic malignant melanoma showed high intensity in the magnetic resonance imaging's T1 weighted image, low intensity in T2 weighted image and very low intensity in T2* weighted image. Positron emission tomographic scans are useful for systemic evaluation of active malignancies. The present case underwent tumor removal following re-bleeding. The patient died of repeated hemorrhage one month after the operation. Intracranial metastatic malignant melanoma has a strong propensity to cause intracerebral hemorrhage leading to clinical deterioration. We think that the development of a therapeutic strategy for the treatment of intracranial metastatic malignant melanoma, including its risk management of intracerebral hemorrhage would be great importance.
authors.affiliation: Department of Neurological Surgery, Kagawa University, Kagawa, Japan.
authors.forename: Aya
authors.initials: A
authors.lastname: Shinomiya
authors.forename: Masaki
authors.initials: M
authors.lastname: Okada
authors.forename: Tetsuhiro
authors.initials: T
authors.lastname: Hatakeyama
authors.forename: Atsushi
authors.initials: A
authors.lastname: Shindo
authors.forename: Takehiro
authors.initials: T
authors.lastname: Nakamura
authors.forename: Masahiko
authors.initials: M
authors.lastname: Kawanishi
authors.forename: Keisuke
authors.initials: K
authors.lastname: Miyake
authors.forename: Nobuyuki
authors.initials: N
authors.lastname: Kawai
authors.forename: Takashi
authors.initials: T
authors.lastname: Tamiya
mesh_terms: D000368:Aged; D001932:Brain Neoplasms / Q000175:diagnosis / Q000556:secondary* / Q000601:surgery; D002543:Cerebral Hemorrhage / Q000209:etiology*; D017809:Fatal Outcome; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008545:Melanoma / Q000175:diagnosis* / Q000601:surgery; D012008:Recurrence