title: Comparison of external beam treatment techniques for T1-2, N0, M0 glottic cancers.
abstract: The purpose of this study was to compare 4 different external beam radiation therapy treatment techniques for the treatment of T1-2, N0, M0 glottic cancers: traditional lateral beams with wedges (3D), 5-field intensity-modulated radiation therapy (IMRT), volumetric modulated arc therapy (VMAT), and proton therapy. Treatment plans in each technique were created for 10 patients using consistent planning parameters. The photon treatment plans were optimized using Philips Pinnacle(3) v.9 and the IMRT and VMAT plans used the Direct Machine Parameter Optimization algorithm. The proton treatment plans were optimized using Varian Eclipse Proton v.8.9. The prescription used for each plan was 63 Gy in 28 fractions. The contours for spinal cord, right carotid artery, left carotid artery, and normal tissue were created with respect to the patient's bony anatomy so that proper comparisons of doses could be made with respect to volume. An example of the different isodose distributions will be shown. The data collection for comparison purposes includes: clinical treatment volume coverage, dose to spinal cord, dose to carotid arteries, and dose to normal tissue. Data comparisons will be displayed graphically showing the maximum, mean, median, and ranges of doses.
authors.affiliation: University of Texas M.D. Anderson Cancer Center, School of Health Professions, Houston, TX 77030, USA.
authors.forename: Pamela
authors.initials: P
authors.lastname: Camingue
authors.forename: Rochelle
authors.initials: R
authors.lastname: Christian
authors.forename: Davin
authors.initials: D
authors.lastname: Ng
authors.forename: Preston
authors.initials: P
authors.lastname: Williams
authors.forename: Mayankkumar
authors.initials: M
authors.lastname: Amin
authors.forename: Dominique L
authors.initials: DL
authors.lastname: Roniger
mesh_terms: D002339:Carotid Arteries; D006801:Humans; D007822:Laryngeal Neoplasms / Q000532:radiotherapy*; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted / Q000379:methods*; D050397:Radiotherapy, Intensity-Modulated; D013116:Spinal Cord