title: Junctional epidermolysis bullosa in a calf.
abstract: A case of epidermolysis bullosa in a calf descendent from a Gir bull and a Gir crossbreed cow is reported. The calf presented with exungulation of all hooves, widespread erosions and crusts on the skin, and ulcers in the oral cavity. Histologically, the skin showed subepidermal separation with clefts occasionally filled with eosinophilic clear fluid, cellular debris, or neutrophils. Ultrastructurally, there was epidermal-dermal separation at the level of the lamina lucida, with the lamina densa attached to the papillary dermis. The hemidesmosomes were poorly defined and small. The clinical, histological, and ultrastructural findings are characteristic of junctional epidermolysis bullosa.
authors.affiliation: Universidade Federal de Campina Grande, Hospital Veterinário, Patos, Paraíba, Brazil.
authors.forename: Gildenor X
authors.initials: GX
authors.lastname: Medeiros
authors.forename: Franklin
authors.initials: F
authors.lastname: Riet-Correa
authors.forename: Anibal G
authors.initials: AG
authors.lastname: Armién
authors.forename: Antônio F M
authors.initials: AF
authors.lastname: Dantas
authors.forename: Glauco J N
authors.initials: GJ
authors.lastname: de Galiza
authors.forename: Sara V D
authors.initials: SV
authors.lastname: Simões
mesh_terms: D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000175:diagnosis* / Q000473:pathology; D004817:Epidermis / Q000648:ultrastructure; D016109:Epidermolysis Bullosa, Junctional / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*; D006724:Hoof and Claw / Q000473:pathology; D046529:Microscopy, Electron, Transmission / Q000662:veterinary; D012867:Skin / Q000473:pathology