title: Quantitative analysis of tooth surface loss associated with gastroesophageal reflux disease: a longitudinal clinical study.
abstract: BACKGROUND
  Acid regurgitation resulting from gastroesophageal reflux disease (GERD) causes dissolution of tooth structure. The authors conducted a longitudinal clinical study to measure tooth surface loss associated with GERD.
  
  
  METHODS
  The authors made replicas of dental impressions obtained from 12 participants with GERD and six control participants at baseline and six months. Using an optical scanner, they digitized the tooth surfaces of these replicas. They then analyzed the volume of tooth surface loss and characterized it as noncontact erosion or erosion/attrition.
  
  
  RESULTS
  Mean (standard deviation) volume loss per tooth in participants with GERD (0.18 [0.12] cubic millimeter) was significantly higher than that in control participants (0.06 [0.03] mm(3); t test; P < .013). Nine participants with GERD exhibited tooth surface loss with characteristics of erosion (noncontact erosion in three participants, erosion/attrition in eight participants).
  
  
  CONCLUSIONS
  Tooth surface loss in participants with GERD was significantly greater than that in control participants. The pattern of surface loss was characteristic of erosion in noncontact areas and around contact areas.
  
  
  CONCLUSIONS
  Anterior and posterior teeth of participants with GERD were affected by erosive tooth wear. In addition, the amount of erosive tooth wear on occlusal surfaces was twice as high when there was evidence of attrition.
authors.affiliation: Department of Restorative Sciences, School of Dentistry, University of Minnesota, Minneapolis, USA. dverslui@uthsc.edu
authors.forename: Daranee
authors.initials: D
authors.lastname: Tantbirojn
authors.forename: Maria R
authors.initials: MR
authors.lastname: Pintado
authors.forename: Antheunis
authors.initials: A
authors.lastname: Versluis
authors.forename: Carol
authors.initials: C
authors.lastname: Dunn
authors.forename: Ralph
authors.initials: R
authors.lastname: Delong
mesh_terms: D000328:Adult; D000368:Aged; D016022:Case-Control Studies; D003743:Dental Enamel / Q000473:pathology*; D005260:Female; D005764:Gastroesophageal Reflux / Q000150:complications*; D006801:Humans; D021621:Imaging, Three-Dimensional; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D010363:Pattern Recognition, Automated; D016628:Replica Techniques; D014077:Tooth Erosion / Q000209:etiology* / Q000473:pathology*; D055815:Young Adult