title: Muscle crush injury of extremity: quantitative elastography with supersonic shear imaging.
abstract: The aim of this study was to determine the characteristic of muscle crush injury at quantitative ultrasonographic elastography using supersonic shear imaging (SSI). Twenty-three New Zealand rabbits underwent crush injury to left hind leg caused by a special balloon cuff device. Conventional ultrasonography and SSI quantitative elastography were performed at both crushed and uncrushed regions of the left hind legs. Quantitative lesion elasticity was measured using the Young's modulus (in kilopascals) at 0.5 h, 2 h, 6 h, 24 h and 72 h after the release of the crushing pressure. Compared with those from the uncrushed regions, both the maximum and mean elasticity values at these time points from the crushed regions were significantly higher (p < 0.001). A receiver operating characteristic (ROC) analysis was employed to assess diagnostic performance. ROC curves showed that extremity crush injury was diagnosed using elasticity value and the greater the elasticity value, the greater the diagnostic value. SSI provides quantitative elasticity measurements, thus, adding complementary information that potentially could help in crush injury characterization with conventional ultrasonography.
authors.affiliation: Department of Ultrasound, Chinese People's Liberation Army General Hospital, Beijing, China.
authors.forename: Faqin
authors.initials: F
authors.lastname: Lv
authors.forename: Jie
authors.initials: J
authors.lastname: Tang
authors.forename: Yukun
authors.initials: Y
authors.lastname: Luo
authors.forename: Yu
authors.initials: Y
authors.lastname: Ban
authors.forename: Rong
authors.initials: R
authors.lastname: Wu
authors.forename: Jiangke
authors.initials: J
authors.lastname: Tian
authors.forename: Tengfei
authors.initials: T
authors.lastname: Yu
authors.forename: Xia
authors.initials: X
authors.lastname: Xie
authors.forename: Tanshi
authors.initials: T
authors.lastname: Li
mesh_terms: D000818:Animals; D003444:Crush Syndrome / Q000000981:diagnostic imaging* / Q000503:physiopathology; D055119:Elastic Modulus; D054459:Elasticity Imaging Techniques / Q000379:methods*; D005260:Female; D006614:Hindlimb / Q000000981:diagnostic imaging / Q000293:injuries* / Q000503:physiopathology*; D008297:Male; D018482:Muscle, Skeletal / Q000000981:diagnostic imaging* / Q000293:injuries* / Q000503:physiopathology; D011817:Rabbits; D033081:Shear Strength