title: Quantum-dot-tagged reduced graphene oxide nanocomposites for bright fluorescence bioimaging and photothermal therapy monitored in situ.
abstract: Quantum-dot-tagged reduced graphene oxide (QD-rGO) nanocomposites (left) internalized into targeted tumor cells display bright fluorescence from the QDs (right); by absorbing NIR radiation incident on the rGO and converting it into heat, they also cause simultaneous cell death and fluorescence reduction (bottom). The nanocomposite is thus capable of tumor imaging, photothermal therapy and in situ monitoring of treatment in progress.
authors.affiliation: Department of Materials Sciences and Engineering, National Chiao Tung University, Hsinchu, Taiwan.
authors.forename: Shang-Hsiu
authors.initials: SH
authors.lastname: Hu
authors.forename: Yu-Wei
authors.initials: YW
authors.lastname: Chen
authors.forename: Wen-Ting
authors.initials: WT
authors.lastname: Hung
authors.forename: I-Wei
authors.initials: IW
authors.lastname: Chen
authors.forename: San-Yuan
authors.initials: SY
authors.lastname: Chen
mesh_terms: D001943:Breast Neoplasms / Q000175:diagnosis* / Q000628:therapy*; D002470:Cell Survival / Q000528:radiation effects; D005260:Female; D005453:Fluorescence; D006108:Graphite / Q000737:chemistry / Q000627:therapeutic use*; D006367:HeLa Cells; D006801:Humans; D006979:Hyperthermia, Induced / Q000379:methods; D053761:Nanocomposites / Q000737:chemistry / Q000627:therapeutic use*; D010084:Oxidation-Reduction; D010087:Oxides / Q000737:chemistry / Q000627:therapeutic use; D010789:Phototherapy / Q000379:methods; D045663:Quantum Dots
chemical_list: D010087:Oxides; D006108:Graphite