title: Single-incision apical and posterior mesh repair: 1-year prospective outcomes.
abstract: OBJECTIVE
  The objective of this study was to assess the safety and efficacy of the Elevate Apical and Posterior single-incision mesh system (SIMS) with IntePro Lite for pelvic organ prolapse repair.
  
  
  METHODS
  This prospective multicenter study included 139 women with ≥ stage II posterior vaginal prolapse and/or apical descent who underwent placement of type I polypropylene mesh through a single transvaginal incision with no external needle passes. Primary endpoint was the percent of patients with posterior and/or apical stage ≤ I ("cure") at follow-up. Secondary endpoints included, but were not limited to, rate of mesh extrusion and disease-specific quality of life outcomes.
  
  
  RESULTS
  At 12 months, objective posterior wall and apical cure rates were 92.5 and 89.2 %, respectively, with an extrusion rate of 6.5 %.
  
  
  CONCLUSIONS
  The SIMS appears to be effective and safe in treating patients with posterior vaginal and/or apical prolapse. The risks and benefits of transvaginal synthetic mesh insertion should be considered.
authors.affiliation: Division of Urogynecology, Department of Obstetrics and Gynecology, Eastern Virginia Medical School, 825 Fairfax Avenue, Suite 310, Norfolk, VA 23507, USA. lukbanjc@evms.edu
authors.forename: James C
authors.initials: JC
authors.lastname: Lukban
authors.forename: Jan-Paul W R
authors.initials: JP
authors.lastname: Roovers
authors.forename: Douglas M
authors.initials: DM
authors.lastname: Vandrie
authors.forename: Ty
authors.initials: T
authors.lastname: Erickson
authors.forename: Samuel
authors.initials: S
authors.lastname: Zylstra
authors.forename: Manish P
authors.initials: MP
authors.lastname: Patel
authors.forename: Robert D
authors.initials: RD
authors.lastname: Moore
mesh_terms: D000368:Aged; D005060:Europe; D005260:Female; D005500:Follow-Up Studies; D013509:Gynecologic Surgical Procedures / Q000009:adverse effects* / Q000379:methods*; D006801:Humans; D008137:Longitudinal Studies; D008875:Middle Aged; D017060:Patient Satisfaction; D056887:Pelvic Organ Prolapse / Q000601:surgery*; D011126:Polypropylenes; D011446:Prospective Studies; D011788:Quality of Life; D018570:Risk Assessment; D013526:Surgical Mesh; D016896:Treatment Outcome; D014481:United States
chemical_list: D011126:Polypropylenes