title: Acellular dermal matrix graft with or without enamel matrix derivative for root coverage in smokers: a randomized clinical study.
abstract: The aim of this randomized controlled clinical study was to compare the use of an acellular dermal matrix graft (ADMG) with or without the enamel matrix derivative (EMD) in smokers to evaluate which procedure would provide better root coverage.
  
  
  
  Nineteen smokers with bilateral Miller Class I or II gingival recessions ≥3 mm were selected. The test group was treated with an association of ADMG and EMD, and the control group with ADMG alone. Probing depth, relative clinical attachment level, gingival recession height, gingival recession width, keratinized tissue width and keratinized tissue thickness were evaluated before the surgeries and after 6 months. Wilcoxon test was used for the statistical analysis at significance level of 5%.
  
  
  
  No significant differences were found between groups in all parameters at baseline. The mean gain recession height between baseline and 6 months and the complete root coverage favored the test group (p = 0.042, p = 0.019 respectively).
  
  
  
  Smoking may negatively affect the results achieved through periodontal plastic procedures; however, the association of ADMG and EMD is beneficial in the root coverage of gingival recessions in smokers, 6 months after the surgery.
authors.affiliation: Department of Oral Surgery and Periodontology, Ribeirão Preto School of Dentistry, University of São Paulo, São Paulo, Brazil.
authors.forename: Luciana B
authors.initials: LB
authors.lastname: Alves
authors.forename: Priscila P
authors.initials: PP
authors.lastname: Costa
authors.forename: Sérgio Luís
authors.initials: SL
authors.lastname: Scombatti de Souza
authors.forename: Márcio F
authors.initials: MF
authors.lastname: de Moraes Grisi
authors.forename: Daniela B
authors.initials: DB
authors.lastname: Palioto
authors.forename: Mario
authors.initials: M
authors.lastname: Taba
authors.forename: Arthur B
authors.initials: AB
authors.lastname: Novaes
mesh_terms: D000328:Adult; D016009:Chi-Square Distribution; D003094:Collagen; D003746:Dental Enamel Proteins / Q000627:therapeutic use*; D005260:Female; D005889:Gingival Recession / Q000188:drug therapy* / Q000601:surgery*; D005893:Gingivoplasty / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D016037:Single-Blind Method; D017768:Skin, Artificial; D012907:Smoking; D018709:Statistics, Nonparametric
chemical_list: C440568:Alloderm; D003746:Dental Enamel Proteins; C109069:enamel matrix proteins; D003094:Collagen