title: Cu(ClO(4))(2)-mediated arene C-H bond halogenations of azacalixaromatics using alkali metal halides as halogen sources.
abstract: Regiospecific halogenation of azacalix[1]arene[3]pyridines at the lower rim position of the benzene ring was achieved from their cross-coupling reaction with cost-effective alkali metal halides through the Cu(ClO(4))(2)-mediated aerobic aryl C-H activation, which gave structurally well-defined aryl-Cu(III) intermediates, and a subsequent C-X bond formation reaction under very mild conditions.
authors.affiliation: Key Laboratory for Bioorganic Phosphorus Chemistry and Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University, Beijing 100084, China.
authors.forename: Bo
authors.initials: B
authors.lastname: Yao
authors.forename: Zu-Li
authors.initials: ZL
authors.lastname: Wang
authors.forename: Hu
authors.initials: H
authors.lastname: Zhang
authors.forename: De-Xian
authors.initials: DX
authors.lastname: Wang
authors.forename: Liang
authors.initials: L
authors.lastname: Zhao
authors.forename: Mei-Xiang
authors.initials: MX
authors.lastname: Wang
mesh_terms: D047250:Calixarenes / Q000737:chemistry*; D003300:Copper / Q000737:chemistry*; D018360:Crystallography, X-Ray; D054879:Halogenation; D006219:Halogens / Q000737:chemistry*; D006860:Hydrogen Bonding; D008672:Metals, Alkali / Q000737:chemistry*; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D011725:Pyridines / Q000737:chemistry*
chemical_list: D006219:Halogens; D008672:Metals, Alkali; D009942:Organometallic Compounds; D011725:Pyridines; D047250:Calixarenes; D003300:Copper