title: Phosphate starvation as an antimicrobial strategy: the controllable toxicity of lanthanum oxide nanoparticles.
abstract: Lanthanum oxide nanoparticles were utilized to scavenge phosphate from microbial growth media for the use of targeted nutrient starvation as an antimicrobial strategy. Only in phosphate poor environments a toxic effect was observed. The effect was shown on Escherichia coli, Staphylococcus carnosus, Penicillium roqueforti, and Chlorella vulgaris.
authors.affiliation: Institute for Chemical and Bioengineering, Department of Chemistry and Applied Biosciences, ETH Zurich, Wolfgang-Pauli-Strasse 10, 8093 Zurich, Switzerland.
authors.forename: Lukas C
authors.initials: LC
authors.lastname: Gerber
authors.forename: Nadine
authors.initials: N
authors.lastname: Moser
authors.forename: Norman A
authors.initials: NA
authors.lastname: Luechinger
authors.forename: Wendelin J
authors.initials: WJ
authors.lastname: Stark
authors.forename: Robert N
authors.initials: RN
authors.lastname: Grass
mesh_terms: D000890:Anti-Infective Agents / Q000737:chemistry / Q000633:toxicity*; D048408:Chlorella vulgaris / Q000187:drug effects; D004926:Escherichia coli / Q000187:drug effects; D007811:Lanthanum / Q000737:chemistry*; D008826:Microbial Sensitivity Tests; D053758:Nanoparticles / Q000737:chemistry / Q000633:toxicity*; D010087:Oxides / Q000737:chemistry*; D010407:Penicillium / Q000187:drug effects; D010710:Phosphates / Q000378:metabolism*; D013211:Staphylococcus aureus / Q000187:drug effects
chemical_list: D000890:Anti-Infective Agents; D010087:Oxides; D010710:Phosphates; C103829:lanthanum oxide; D007811:Lanthanum