title: A POSS-based supramolecular amphiphile and its hierarchical self-assembly behaviors.
abstract: A polyhedral oligomeric silsesquioxane (POSS)-based supramolecular amphiphile is prepared from the host-guest inclusion complexation between a mono adamantane-functionalized POSS (AD-POSS) and a β-cyclodextrin oligomer (P(β-CD)). Assisted by the interface of H(2)O/toluene, the obtained supramolecular hybrids self-assemble into stable hollow nanospheres with thick walls. These hollow nanospheres aggregate together into a sphere layer through a spin coating technique, which then further transforms into a thin porous film containing nanometer-scale holes. The hollow nanospheres have a low cytotoxicity. The in vitro cell culture indicates the nanoporous films promote adhesion and proliferation of cells. The self-assembly morphologies and structures have been carefully characterized by SEM, TEM, AFM, DLS, XPS and water-contact angle measurements, and the self-assembly mechanism has also been discussed.
authors.affiliation: School of Chemistry and Chemical Engineering, State Key Laboratory of Metal Matrix Composites, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai 200240, P R China.
authors.forename: Binbin
authors.initials: B
authors.lastname: Jiang
authors.forename: Wei
authors.initials: W
authors.lastname: Tao
authors.forename: Xin
authors.initials: X
authors.lastname: Lu
authors.forename: Yong
authors.initials: Y
authors.lastname: Liu
authors.forename: Haibao
authors.initials: H
authors.lastname: Jin
authors.forename: Yan
authors.initials: Y
authors.lastname: Pang
authors.forename: Xiaoyi
authors.initials: X
authors.lastname: Sun
authors.forename: Deyue
authors.initials: D
authors.lastname: Yan
authors.forename: Yongfeng
authors.initials: Y
authors.lastname: Zhou
mesh_terms: D000218:Adamantane / Q000737:chemistry; D000818:Animals; D002460:Cell Line; D002470:Cell Survival / Q000187:drug effects; D004811:Epichlorohydrin / Q000737:chemistry; D008567:Membranes, Artificial; D051379:Mice; D054118:Nanospheres / Q000737:chemistry / Q000648:ultrastructure; D017646:Organosilicon Compounds / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D010316:Particle Size; D058105:Polymerization; D011108:Polymers / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D016062:Porosity; D013501:Surface-Active Agents / Q000138:chemical synthesis*; D047392:beta-Cyclodextrins / Q000737:chemistry
chemical_list: D008567:Membranes, Artificial; D017646:Organosilicon Compounds; D011108:Polymers; D013501:Surface-Active Agents; D047392:beta-Cyclodextrins; D004811:Epichlorohydrin; D000218:Adamantane