title: Acquisition of hydrogenosomal presequences: examples from Trichomonas vaginalis.
abstract: Presequences play an important role in protein import into mitochondria-like organelles. Acquisition pathways have been revealed for some mitochondrial presequences, but little is known about hydrogenosomal presequences. Here we investigated the hydrogenosomal proteins of Trichomonas vaginalis and suggest that several hydrogenosomal presequences probably evolved from pre-existing sequences that were thereafter modified.
authors.affiliation: Center of Biomedical and Health, Hangzhou Normal University, Hangzhou, China.
authors.forename: Dongliang
authors.initials: D
authors.lastname: Yu
authors.forename: Yue
authors.initials: Y
authors.lastname: Wang
authors.forename: Xu
authors.initials: X
authors.lastname: Fang
authors.forename: Songnian
authors.initials: S
authors.lastname: Hu
authors.forename: Petrus
authors.initials: P
authors.lastname: Tang
authors.forename: Yan
authors.initials: Y
authors.lastname: Fu
mesh_terms: D000595:Amino Acid Sequence; D008969:Molecular Sequence Data; D015388:Organelles / Q000201:enzymology; D021382:Protein Sorting Signals; D021381:Protein Transport; D015800:Protozoan Proteins / Q000235:genetics* / Q000378:metabolism*; D016415:Sequence Alignment; D014246:Trichomonas vaginalis / Q000201:enzymology* / Q000235:genetics*
chemical_list: D021382:Protein Sorting Signals; D015800:Protozoan Proteins