title: Ascorbic acid, cognitive function, and Alzheimer's disease: a current review and future direction.
abstract: This narrative review appraises the human and animal studies implicating ascorbic acid (AA) in normal cognitive function and Alzheimer's disease. A research framework for how nutrition affects brain aging is proposed with emphasis on AA intake, status, metabolism, and transport into brain tissue. A final synopsis highlights areas for future research regarding AA nourishment and healthy brain aging.
authors.affiliation: Department of Neurology, CR-131, Oregon Health and Science University, Portland, OR, USA. bowmang@ohsu.edu
authors.forename: Gene L
authors.initials: GL
authors.lastname: Bowman
mesh_terms: D000544:Alzheimer Disease / Q000378:metabolism* / Q000503:physiopathology; D000818:Animals; D001205:Ascorbic Acid / Q000378:metabolism*; D001921:Brain / Q000378:metabolism / Q000503:physiopathology; D003071:Cognition / Q000502:physiology*; D006801:Humans
chemical_list: D001205:Ascorbic Acid