title: Hip fracture incidence from 1981 to 2009 in the Czech Republic as a basis of the country-specific FRAX model.
abstract: The aim of this study was to calculate rates of hospitalization for hip fracture and the incidence of hip fractures in the Czech Republic over a period of 29 years. A second aim was to use the most recent data to populate a FRAX(®) model for the assessment of fracture probability in individual patients. Data on hospitalizations for hip fracture (1981-2009) and number of women and men with hip fractures (2000-2009) were obtained, and incidences were computed for the entire population ≥50 years of age. Incidence of hospitalization for hip fracture in the Czech population aged ≥50 years increased progressively by calendar year. Age-standardized incidence of hip fractures increased to 2004 but leveled off thereafter and decreased after 2005. Data for hip fracture risk in 2008 and 2009 and the death hazard were used to populate a Czech-specific FRAX model for the computation of 10-year fracture probability. The customized FRAX model, using the verified epidemiological data, will be used to identify patients at increased fracture risk.
authors.affiliation: Institute of Rheumatology, Prague, and Department of Rheumatology, Charles University, Prague, Czech Republic. stepan@revma.cz
authors.forename: Jan J
authors.initials: JJ
authors.lastname: Stepan
authors.forename: Jan
authors.initials: J
authors.lastname: Vaculik
authors.forename: Karel
authors.initials: K
authors.lastname: Pavelka
authors.forename: Jan
authors.initials: J
authors.lastname: Zofka
authors.forename: Helena
authors.initials: H
authors.lastname: Johansson
authors.forename: John A
authors.initials: JA
authors.lastname: Kanis
mesh_terms: D000368:Aged; D015519:Bone Density / Q000502:physiology; D018153:Czech Republic / Q000453:epidemiology; D005260:Female; D006620:Hip Fractures / Q000453:epidemiology* / Q000209:etiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010024:Osteoporosis / Q000150:complications / Q000453:epidemiology; D012307:Risk Factors