title: [The influence shuxuetong on the membrane viscoelasticity of erythrocyte taken from patients with chronic pulmonary heart disease].
abstract: The present paper was aimed to explore the effect of Shuxuetong on the membrane viscoelasticity of erythrocyte taken from the acute phase patients suffering from chronic pulmonary heart disease. The membrane viscoelasticity of erythrocyte was taken from the acute phase patients suffering from chronic pulmonary heart disease. The changes of membrane viscoelasticity of erythrocyte after treated with shuxuetong were detected by micropipette aspiration technique. The results showed that the Shuxuetong of certain concentration could cause the decrease of membrane elastic modulus and viscous coefficients in acute phase patients suffering from chronic pulmonary heart disease. The study offers experimental evidences that the comprehensive treatment of pulmonary heart disease should involve the drug or measure to improve the erythrocyte deformability.
authors.affiliation: Department of Respiratory, Second Affiliated Hospital of Chongqing Medicine University, Chongqing 400010, China. zhangyanyan1977@hotmail.com
authors.forename: Yan
authors.initials: Y
authors.lastname: Zhang
authors.forename: Tonghua
authors.initials: T
authors.lastname: Mei
authors.forename: Zezhi
authors.initials: Z
authors.lastname: Wu
mesh_terms: D000368:Aged; D001809:Blood Viscosity / Q000187:drug effects*; D002908:Chronic Disease; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D004548:Elasticity / Q000187:drug effects*; D004907:Erythrocyte Deformability / Q000502:physiology; D004910:Erythrocyte Membrane / Q000502:physiology*; D004912:Erythrocytes / Q000502:physiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008517:Phytotherapy; D011660:Pulmonary Heart Disease / Q000097:blood / Q000188:drug therapy*
chemical_list: D004365:Drugs, Chinese Herbal; C532053:shuxuetong