title: GOLVEN secretory peptides regulate auxin carrier turnover during plant gravitropic responses.
abstract: Growth and development are coordinated by an array of intercellular communications. Known plant signaling molecules include phytohormones and hormone peptides. Although both classes can be implicated in the same developmental processes, little is known about the interplay between phytohormone action and peptide signaling within the cellular microenvironment. We show that genes coding for small secretory peptides, designated GOLVEN (GLV), modulate the distribution of the phytohormone auxin. The deregulation of the GLV function impairs the formation of auxin gradients and alters the reorientation of shoots and roots after a gravity stimulus. Specifically, the GLV signal modulates the trafficking dynamics of the auxin efflux carrier PIN-FORMED2 involved in root tropic responses and meristem organization. Our work links the local action of secretory peptides with phytohormone transport.
authors.affiliation: Department of Plant Systems Biology, VIB, Ghent, Belgium.
authors.forename: Ryan
authors.initials: R
authors.lastname: Whitford
authors.forename: Ana
authors.initials: A
authors.lastname: Fernandez
authors.forename: Ricardo
authors.initials: R
authors.lastname: Tejos
authors.forename: Amparo Cuéllar
authors.initials: AC
authors.lastname: Pérez
authors.forename: Jürgen
authors.initials: J
authors.lastname: Kleine-Vehn
authors.forename: Steffen
authors.initials: S
authors.lastname: Vanneste
authors.forename: Andrzej
authors.initials: A
authors.lastname: Drozdzecki
authors.forename: Johannes
authors.initials: J
authors.lastname: Leitner
authors.forename: Lindy
authors.initials: L
authors.lastname: Abas
authors.forename: Maarten
authors.initials: M
authors.lastname: Aerts
authors.forename: Kurt
authors.initials: K
authors.lastname: Hoogewijs
authors.forename: Pawel
authors.initials: P
authors.lastname: Baster
authors.forename: Ruth
authors.initials: R
authors.lastname: De Groodt
authors.forename: Yao-Cheng
authors.initials: YC
authors.lastname: Lin
authors.forename: Véronique
authors.initials: V
authors.lastname: Storme
authors.forename: Yves
authors.initials: Y
authors.lastname: Van de Peer
authors.forename: Tom
authors.initials: T
authors.lastname: Beeckman
authors.forename: Annemieke
authors.initials: A
authors.lastname: Madder
authors.forename: Bart
authors.initials: B
authors.lastname: Devreese
authors.forename: Christian
authors.initials: C
authors.lastname: Luschnig
authors.forename: Jiří
authors.initials: J
authors.lastname: Friml
authors.forename: Pierre
authors.initials: P
authors.lastname: Hilson
mesh_terms: D017360:Arabidopsis / Q000235:genetics / Q000378:metabolism*; D029681:Arabidopsis Proteins / Q000378:metabolism*; D002352:Carrier Proteins / Q000235:genetics / Q000378:metabolism*; D060833:Cellular Microenvironment / Q000502:physiology; D018506:Gene Expression Regulation, Plant; D018522:Gravitropism; D007210:Indoleacetic Acids / Q000378:metabolism*; D018517:Plant Roots / Q000235:genetics / Q000378:metabolism / Q000502:physiology; D015398:Signal Transduction / Q000235:genetics
chemical_list: D029681:Arabidopsis Proteins; D002352:Carrier Proteins; D007210:Indoleacetic Acids; C117013:AT5G57090 protein, Arabidopsis