title: 9,10-seco-9,19-cyclolanostane triterpene from Salix caprea L. (goat willow).
abstract: Chemical investigation of low polar solvent extract of Salix caprea through chromatographic techniques led to the isolation of new triterpene as 1α,3β,25-trihydroxy-9(11)-ene-16-one-9,10-seco-9,19-cyclolanostane (1) along with fatty alcohols. The structure of compound 1 was established by IR, HRESI/MS and NMR including 1D and 2D experiments. The compound 1 showed moderate in vitro antiplasmodial activity.
authors.affiliation: National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, School of Pharmacy, The University of Mississippi, University, MS 38677, USA. mtantry@olemiss.edu
authors.forename: Mudasir A
authors.initials: MA
authors.lastname: Tantry
authors.forename: Saba
authors.initials: S
authors.lastname: Shah
authors.forename: Mohammad Y
authors.initials: MY
authors.lastname: Dar
authors.forename: Mohammad M
authors.initials: MM
authors.lastname: Mir
authors.forename: Khalid
authors.initials: K
authors.lastname: Ghazanfar
authors.forename: Faheem A
authors.initials: FA
authors.lastname: Sheikh
authors.forename: Mohammad A
authors.initials: MA
authors.lastname: Khuroo
authors.forename: Seema
authors.initials: S
authors.lastname: Akbar
mesh_terms: D002725:Chloroform; D002845:Chromatography; D035264:Flowers / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D010936:Plant Extracts / Q000032:analysis* / Q000302:isolation & purification / Q000494:pharmacology; D010963:Plasmodium falciparum / Q000187:drug effects; D032108:Salix / Q000737:chemistry*; D014315:Triterpenes / Q000032:analysis* / Q000302:isolation & purification / Q000494:pharmacology
chemical_list: C557046:9,10-seco-9,19-cyclolanostane xyloside; D010936:Plant Extracts; D014315:Triterpenes; D002725:Chloroform