title: A case of anorexia nervosa with disseminated intravascular coagulation syndrome.
abstract: A 36-year-old Japanese woman with anorexia nervosa (AN) was admitted to our department because of severe emaciation. Although we were thorough in her clinical management and were careful to avoid precipitating refeeding syndrome, disseminated intravascular coagulation (DIC) developed 3 weeks after hospitalization. We treated her for DIC with sepsis using anticoagulants, protease inhibitors, antithrombin, and platelet concentrate transfusion. To treat her bacterial infection, we administered antimicrobial drugs and immunoglobulin. We began probiotic and prebiotic (synbiotics) treatment for bacterial translocation. We think that the prevention of sepsis via bacterial translocation is an important aspect of care for patients with severe AN in addition to the prevention of refeeding syndrome.
authors.affiliation: Department of Psychosomatic Internal Medicine, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima 890-8520, Japan.
authors.forename: Izumi
authors.initials: I
authors.lastname: Haruta
authors.forename: Akihiro
authors.initials: A
authors.lastname: Asakawa
authors.forename: Kazuma
authors.initials: K
authors.lastname: Ogiso
authors.forename: Haruka
authors.initials: H
authors.lastname: Amitani
authors.forename: Marie
authors.initials: M
authors.lastname: Amitani
authors.forename: Minglun
authors.initials: M
authors.lastname: Tsai
authors.forename: Satoshi
authors.initials: S
authors.lastname: Hamada
authors.forename: Akio
authors.initials: A
authors.lastname: Inui
mesh_terms: D000328:Adult; D000856:Anorexia Nervosa / Q000150:complications*; D000925:Anticoagulants / Q000627:therapeutic use; D000990:Antithrombin III / Q000627:therapeutic use; D000991:Antithrombins / Q000627:therapeutic use; D004211:Disseminated Intravascular Coagulation / Q000150:complications* / Q000188:drug therapy; D005260:Female; D006801:Humans; D018805:Sepsis / Q000188:drug therapy; D016896:Treatment Outcome
chemical_list: D000925:Anticoagulants; D000991:Antithrombins; D000990:Antithrombin III