title: Nasopharyngeal necrosis after chronic opioid (oxycodone/acetaminophen) insufflation.
abstract: Nasopharyngeal necrosis resulting from narcotic insufflation is a recognized phenomenon, but cocaine use is more commonly associated with this pathology than opioid abuse. Physical exam findings associated with severe tissue destruction are not routinely seen on physical examination or available in the medical literature. We present a case of chronic oxycodone/acetaminophen insufflation and images of a defect in the soft palate.
authors.affiliation: Department of Emergency Medicine, Division of Medical Toxicology, University of Massachusetts Medical Center, Worcester, MA 01655, USA. crosen5@gmail.com
authors.forename: Christopher D
authors.initials: CD
authors.lastname: Rosenbaum
authors.forename: Katherine L
authors.initials: KL
authors.lastname: Boyle
authors.forename: Edward W
authors.initials: EW
authors.lastname: Boyer
mesh_terms: D000082:Acetaminophen / Q000506:poisoning*; D000328:Adult; D004338:Drug Combinations; D005260:Female; D006801:Humans; D007327:Insufflation; D009305:Nasopharynx / Q000187:drug effects* / Q000473:pathology*; D009336:Necrosis; D010098:Oxycodone / Q000506:poisoning*
chemical_list: D004338:Drug Combinations; C514822:oxycodone-acetaminophen; D000082:Acetaminophen; D010098:Oxycodone