title: Quantum dot (QD)-modified carbon tape electrodes for reproducible electrochemiluminescence (ECL) emission on a paper-based platform.
abstract: Stable and sensitive electrochemiluminescence (ECL) detection relies on successful immobilization of quantum dots (QDs) on working electrodes. Herein, we report a new technique to apply double-sided carbon adhesive tape as the working electrode to improve the stability and reproducibility of QD-based ECL emission. CdS QD-modified electrodes were prepared by dropping and drying CdS QD suspension on the carbon adhesive tape supported by indium tin oxide (ITO) glass. The ECL detection was performed with the prepared electrode on a paper-based platform. We tested our system using H(2)O(2) of various concentrations and demonstrated that consistent ECL emission could be obtained. We attribute stable and reproducible ECL emission to the robust attachment of CdS QDs on the carbon adhesive tape. The proposed method could be used to quantify the concentration of dopamine from 1 μM to 10 mM based on the quenching effect of dopamine on ECL emission of CdS QD system using H(2)O(2) as the coreactant. Our approach addressed the problem in the integration of stable QD-based ECL detection with portable paper-based analytical devices. The similar design offers great potential for low-cost electrochemical and ECL analytical instruments.
authors.affiliation: Institute of Analytical Chemistry for Life Science, School of Public Health, Nantong University, Nantong, People's Republic of China.
authors.forename: Chuan-Guo
authors.initials: CG
authors.lastname: Shi
authors.forename: Xia
authors.initials: X
authors.lastname: Shan
authors.forename: Zhong-Qin
authors.initials: ZQ
authors.lastname: Pan
authors.forename: Jing-Juan
authors.initials: JJ
authors.lastname: Xu
authors.forename: Chang
authors.initials: C
authors.lastname: Lu
authors.forename: Ning
authors.initials: N
authors.lastname: Bao
authors.forename: Hai-Ying
authors.initials: HY
authors.lastname: Gu
mesh_terms: D019187:Cadmium Compounds / Q000737:chemistry; D002244:Carbon / Q000737:chemistry*; D004298:Dopamine / Q000032:analysis*; D055664:Electrochemical Techniques / Q000295:instrumentation*; D004566:Electrodes; D004867:Equipment Design; D006861:Hydrogen Peroxide / Q000737:chemistry; D008163:Luminescent Measurements / Q000295:instrumentation*; D010209:Paper; D045663:Quantum Dots; D015203:Reproducibility of Results; D018036:Selenium Compounds / Q000737:chemistry; D012680:Sensitivity and Specificity
chemical_list: D019187:Cadmium Compounds; D018036:Selenium Compounds; D002244:Carbon; C058667:cadmium selenide; D006861:Hydrogen Peroxide; D004298:Dopamine