title: Stent thrombosis in a clopidogrel nonresponder.
abstract: Stent thrombosis is a known complication of percutaneous coronary intervention (PCI) following coronary stent deployment. Dual antiplatelet therapy is standard of care following PCI, however, recent studies demonstrate marked variability in platelet response to clopidogrel. This case study explores the management of a clopidogrel nonresponder who presented with recurrent stent thrombosis despite traditional pharmacologic management.
authors.affiliation: The University of Texas Health Science Center at Houston School of Nursing, 77030, USA. Patrick.A.Laird@uth.tmc.edu
authors.forename: Patrick A
authors.initials: PA
authors.lastname: Laird
authors.forename: Susan D
authors.initials: SD
authors.lastname: Ruppert
mesh_terms: D000368:Aged; D000077144:Clopidogrel; D003328:Coronary Thrombosis / Q000188:drug therapy / Q000209:etiology / Q000451:nursing*; D003422:Critical Care; D004351:Drug Resistance; D005260:Female; D006801:Humans; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use*; D015607:Stents / Q000009:adverse effects*; D013988:Ticlopidine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D016896:Treatment Outcome
chemical_list: D010975:Platelet Aggregation Inhibitors; D000077144:Clopidogrel; D013988:Ticlopidine