title: Malignant peripheral nerve sheath tumour of the urinary bladder in a cat.
abstract: A 14-year-old domestic shorthair cat presented with a 5-month history of urinary incontinence and inappro-priate elimination. Ultrasonography revealed a well-marginated, vascular mass of mixed echogenicity ex-tending from the dorsal wall of the urinary bladder into the lumen. Partial cystectomy was performed for re-moval of the urinary bladder mass; histopathological evaluation revealed a spindle cell neoplasm with a prominent palisading pattern. Histomorphologic features and immunohistochemical demonstration of vimentin, glial fibrillary acidic protein and S-100 protein, combined with negativity for smooth muscle actin and desmin were consistent with malignant peripheral nerve sheath tumour. This case report describes a novel location of malignant peripheral nerve sheath tumour; to the authors' knowledge, the bladder has not been described as a site of origin in the cat or any other domestic species.
authors.affiliation: Department of Surgery, Animal Medical Center, New York, NY 10065, USA.
authors.forename: P R
authors.initials: PR
authors.lastname: Pavia
authors.forename: M E
authors.initials: ME
authors.lastname: Havig
authors.forename: T A
authors.initials: TA
authors.lastname: Donovan
authors.forename: D
authors.initials: D
authors.lastname: Craft
mesh_terms: D000818:Animals; D002371:Cat Diseases / Q000175:diagnosis* / Q000601:surgery; D002415:Cats; D015653:Cystectomy / Q000662:veterinary; D008297:Male; D018317:Nerve Sheath Neoplasms / Q000175:diagnosis / Q000601:surgery / Q000662:veterinary*; D001749:Urinary Bladder Neoplasms / Q000175:diagnosis / Q000601:surgery / Q000662:veterinary*