title: A current update on osteonecrosis of the jaw and bisphosphonates.
abstract: Bisphosphonates are effective drugs used to treat important medical conditions affecting the skeleton, such as malignancy and osteoporosis. Bisphosphonate-associated osteonecrosis of the jaw (BONJ) is a rare but painful condition that can affect quality of life. Healthcare professionals need to be aware of this potential side-effect of bisphosphonates, as well as ways to minimize its occurrence.
authors.affiliation: University of Birmingham School of Dentistry, St Chad's Queensway, Birmingham B4 6NN, UK.
authors.forename: Yazdana
authors.initials: Y
authors.lastname: Arrain
authors.forename: Tahir
authors.initials: T
authors.lastname: Masud
mesh_terms: D000911:Antibodies, Monoclonal / Q000009:adverse effects; D061067:Antibodies, Monoclonal, Humanized; D059266:Bisphosphonate-Associated Osteonecrosis of the Jaw / Q000145:classification / Q000209:etiology* / Q000517:prevention & control; D050071:Bone Density Conservation Agents / Q000009:adverse effects*; D000069448:Denosumab; D003937:Diagnosis, Differential; D004164:Diphosphonates / Q000009:adverse effects*; D006801:Humans; D011788:Quality of Life; D053245:RANK Ligand / Q000037:antagonists & inhibitors
chemical_list: D000911:Antibodies, Monoclonal; D061067:Antibodies, Monoclonal, Humanized; D050071:Bone Density Conservation Agents; D004164:Diphosphonates; D053245:RANK Ligand; D000069448:Denosumab