title: Carbamate derivatives and sesquiterpenoids from the South China Sea gorgonian Melitodes squamata.
abstract: Five carbamate derivatives, obtucarbamates C and D (1, 2), dimethyl ((carbonylbis(azanediyl))bis(2-methyl-5,1-phenylene))dicarbamate (3), obtucarbamates A and B (4, 5), and four aromadendrane-type sesquiterpenoids, (+)-4β-N-methenetauryl-10β-methoxy-1β,5α,6β,7β-aromadendrane (6), (-)-4β-N-methenetauryl-10β-methoxy-1β,5β,6α,7α-aromadendrane (7), (-)-4α,10β-aromadendranediol (8), (+)-4β,10β-aromadendranediol (9) were obtained from the South China Sea gorgonian coral Melitodes squamata Nutting. Compounds 1, 2, 6, and 7 were new, and their structures were established by spectroscopic analyses. Compounds 6 and 7 contained a taurine group that was rarely found in marine natural compounds, and 7 showed moderate antibacterial activity. The possible biosynthesis routes of 1-5 were conjectured.
authors.affiliation: Key Laboratory of Marine Bio-resources Sustainable Utilization/Guangdong Key Laboratory of Marine Materia Medica/RNAM Center for Marine Microbiology, South China Sea Institute of Oceanology, The Chinese Academy of Sciences, 164 West Xingang Road, Guangzhou 510301 Guangdong, China.
authors.forename: Li-Si
authors.initials: LS
authors.lastname: Huang
authors.forename: Fei
authors.initials: F
authors.lastname: He
authors.forename: Hui
authors.initials: H
authors.lastname: Huang
authors.forename: Xiao-Yong
authors.initials: XY
authors.lastname: Zhang
authors.forename: Shu-Hua
authors.initials: SH
authors.lastname: Qi