title: [Comparison of bupivacaine and levobupivacaine with epidural technique for labor analgesia].
abstract: OBJECTIVE
  The labor pain is one of the most severe pains that a woman could ever be suffered. Today, many medical and psychological methods are used in an effort to reduce labor pain.Epidural analgesia is the best current method used for the purposes of obstetric analgesia.
  
  
  METHODS
  The study was carried out on 60 ASA-I pregnant women whose 3 to 6 cm of cervical dilatation, treated in Health Ministry Istanbul Education and Research Hospital, Gynecology and Obstetrics Clinic, within vaginal labor process. With use of patient controlled epidural analgesia method, the bupivacaine combined with low dose fentanyl were administered to 30 pregnant women (Group B). Levobupivacaine, combined with low dose fentanyl applied with the same method was administered to another 30 pregnant women (Group L). Between the two groups, the hemodynamic parameters on the mother and fetus, the course of the labor process, severity of pain, its influences on newborn and mother satisfaction were compared.
  
  
  RESULTS
  In our study, there was no difference as to motor block development between groups, but the sensory block was monitored less in group L at the minutes 15, 30, 45 and 90. Furthermore, the 5 minutes pain score was found lower in group L. The VAS values at the other times were similar between groups.
  
  
  CONCLUSIONS
  In conclusion, with the usage of 0.125% bupivacaine or 0.125% levobupivacaine, sufficient labor analgesia is achieved with patient controlled epidural analgesia method at the same side effect frequency. Consequently, both local analgesic medicines are seemed to be safely used in labor analgesia.
authors.affiliation: Department of Anesthesiology and Reanimation, İstanbul Training and Research Hospital, Turkey.
authors.forename: Reyhan
authors.initials: R
authors.lastname: Arslantaş
authors.forename: Mustafa Kemal
authors.initials: MK
authors.lastname: Arslantaş
authors.forename: Emine
authors.initials: E
authors.lastname: Ozyuvaci
mesh_terms: D000328:Adult; D015360:Analgesia, Epidural / Q000379:methods*; D016362:Analgesia, Obstetrical / Q000379:methods*; D016058:Analgesia, Patient-Controlled; D000701:Analgesics, Opioid / Q000008:administration & dosage; D000779:Anesthetics, Local / Q000008:administration & dosage*; D002045:Bupivacaine / Q000008:administration & dosage* / Q000031:analogs & derivatives; D005260:Female; D005283:Fentanyl / Q000008:administration & dosage; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D007231:Infant, Newborn; D048949:Labor Pain / Q000188:drug therapy*; D000077554:Levobupivacaine; D010147:Pain Measurement; D017060:Patient Satisfaction; D011247:Pregnancy
chemical_list: D000701:Analgesics, Opioid; D000779:Anesthetics, Local; D000077554:Levobupivacaine; D005283:Fentanyl; D002045:Bupivacaine