title: A CT-analogous scheme for time-domain diffuse fluorescence tomography.
abstract: A fiber-based non-contact scheme of the time-domain diffuse fluorescence yield and lifetime tomography is described that combines the time-correlated single photon counting technique for high-sensitive, time-resolved detection and CT-analogous configuration for large data-set collection. A pilot validation of the methodology is performed for two-dimensional scenarios using simulated and experimental data. The results demonstrated the efficacy of the proposed scheme in improving the image quality.
authors.affiliation: College of Precision Instrument and Optoelectronics Engineering, Tianjin University, Tianjin, China. gaofeng@tju.edu.cn
authors.forename: Feng
authors.initials: F
authors.lastname: Gao
authors.forename: Jiao
authors.initials: J
authors.lastname: Li
authors.forename: Wei
authors.initials: W
authors.lastname: Zhang
authors.forename: Xi
authors.initials: X
authors.lastname: Yi
authors.forename: Xin
authors.initials: X
authors.lastname: Wang
authors.forename: Limin
authors.initials: L
authors.lastname: Zhang
authors.forename: Zhongxing
authors.initials: Z
authors.lastname: Zhou
authors.forename: Huijuan
authors.initials: H
authors.lastname: Zhao
mesh_terms: D019047:Phantoms, Imaging; D015203:Reproducibility of Results; D013050:Spectrometry, Fluorescence / Q000295:instrumentation / Q000379:methods*; D014054:Tomography / Q000295:instrumentation / Q000379:methods*; D014057:Tomography, X-Ray Computed / Q000295:instrumentation / Q000379:methods*