title: Synthetic strategies to terpene quinones/hydroquinones.
abstract: The cytotoxic and antiproliferative properties of many natural sesquiterpene-quinones and -hydroquinones from sponges offer promising opportunities for the development of new drugs. A review dealing with different strategies for obtaining bioactive terpenyl quinones/hydroquinones is presented. The different synthetic approches for the preparation of the most relevant quinones/hydroquinones are described.
authors.affiliation: Farmacy Faculty and Institute of Science and Technology Studies, Campus Miguel de Unamuno, Salamanca University, 37007 Salamanca, Spain.
authors.forename: Marina
authors.initials: M
authors.lastname: Gordaliza
mesh_terms: D000818:Animals; D000890:Anti-Infective Agents / Q000138:chemical synthesis; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000138:chemical synthesis; D000970:Antineoplastic Agents / Q000138:chemical synthesis; D002626:Chemistry, Pharmaceutical; D006801:Humans; D006873:Hydroquinones / Q000138:chemical synthesis*; D011809:Quinones / Q000138:chemical synthesis*; D013729:Terpenes / Q000138:chemical synthesis*
chemical_list: D000890:Anti-Infective Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D000970:Antineoplastic Agents; D006873:Hydroquinones; D011809:Quinones; D013729:Terpenes