title: Elimination of carbamazepine in a non-sterile fungal bioreactor.
abstract: A properly configured bioreactor is in need to transfer the fungal biodegradation of recalcitrant pollutants into real applications. In this study, a novel plate bioreactor was designed to eliminate carbamazepine (CBZ), a widely concerned pharmaceutical, with the white rot fungus Phanerochaete chrysosporium grown on polyether foam under non-sterile conditions. The bioreactor was operated in both sequence batch and continuous modes. It was found that the sufficient supply with nutrients is crucial for an effective elimination of CBZ. Given the conditions, a high elimination of CBZ (60-80%) was achieved. The effective elimination was stable in a continuous operation for a long term (around 100 days). The high elimination of CBZ could also be achieved under real conditions with the effluent from a municipal wastewater treatment plant.
authors.affiliation: Chair of Environmental Process Engineering, Department of Environmental Technology, Technical University of Berlin, Germany. yongjun.zhang@tu-berlin.de
authors.forename: Yongjun
authors.initials: Y
authors.lastname: Zhang
authors.forename: Sven-Uwe
authors.initials: SU
authors.lastname: Geissen
mesh_terms: D000327:Adsorption; D061249:Batch Cell Culture Techniques; D001673:Biodegradation, Environmental; D019149:Bioreactors / Q000382:microbiology*; D001711:Biotransformation; D002220:Carbamazepine / Q000302:isolation & purification*; D052918:Environmental Restoration and Remediation / Q000295:instrumentation* / Q000379:methods*; D006863:Hydrogen-Ion Concentration; D009584:Nitrogen / Q000032:analysis; D010100:Oxygen / Q000032:analysis; D020075:Phanerochaete / Q000502:physiology*; D013242:Sterilization; D014865:Waste Disposal, Fluid
chemical_list: D002220:Carbamazepine; D009584:Nitrogen; D010100:Oxygen