title: Formation of optically pure cyclic amines by intramolecular conjugate displacement.
abstract: Intramolecular conjugate displacement (ICD) has been applied to the Morita-Baylis-Hillman adducts formed from (5S)-5-(l-menthyloxy)-2(5H)-furanone and aldehydes that carry a protected β- or γ-amino group. DIBAL-H reduction of the resulting ICD products releases optically pure six- or seven-membered cyclic amines having a stereogenic center α to nitrogen.
authors.affiliation: Chemistry Department, University of Alberta, Edmonton, Alberta T6G 2G2, Canada.
authors.forename: Ping
authors.initials: P
authors.lastname: Cheng
authors.forename: Derrick L J
authors.initials: DL
authors.lastname: Clive