title: Unusual regression of severe recurrent lymphatic malformation of a face after contraception and pregnancy.
abstract: We report the case of a female who had suffered from progressive lymphatic malformation in the orbito-temporal region since childhood. Many surgical interventions were performed, including radical excision and shunt drainage. Despite aggressive surgical treatment, recurrence was observed after every intervention. Eventually, the condition regressed after the patient began taking a contraceptive. Moreover, it virtually disappeared after pregnancy.
authors.affiliation: Department of Plastic Surgery, 1st Medical Faculty, Prague, Czech Republic. mestak@gmail.com
authors.forename: Ondrej
authors.initials: O
authors.lastname: Mestak
authors.forename: Jan
authors.initials: J
authors.lastname: Mestak
authors.forename: Katerina
authors.initials: K
authors.lastname: Pokorna
authors.forename: Josef
authors.initials: J
authors.lastname: Bruna
authors.forename: Andrej
authors.initials: A
authors.lastname: Sukop
mesh_terms: D000328:Adult; D003277:Contraceptives, Oral, Combined / Q000008:administration & dosage* / Q000627:therapeutic use; D004338:Drug Combinations; D004997:Ethinyl Estradiol / Q000008:administration & dosage* / Q000627:therapeutic use; D005153:Facial Neoplasms / Q000150:complications / Q000601:surgery / Q000628:therapy; D005260:Female; D006801:Humans; D008202:Lymphangioma / Q000150:complications / Q000601:surgery / Q000628:therapy; D044148:Lymphatic Abnormalities / Q000150:complications / Q000503:physiopathology* / Q000601:surgery / Q000628:therapy*; D009644:Norgestrel / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D009915:Orbit; D011183:Postoperative Complications / Q000517:prevention & control; D011247:Pregnancy; D011248:Pregnancy Complications / Q000517:prevention & control; D012008:Recurrence; D012074:Remission Induction; D013701:Temporal Bone; D055815:Young Adult
chemical_list: D003277:Contraceptives, Oral, Combined; D004338:Drug Combinations; C109079:norgestimate, ethinyl estradiol drug combination; D009644:Norgestrel; D004997:Ethinyl Estradiol