title: [Anemia in heart failure: its usefulness as prognosis or comorbidity marker: GESAIC-2 study].
abstract: OBJECTIVE
  To assess the prognosis and etiology of anemia in heart failure (HF).
  
  
  METHODS
  Prospective multicenter cohort of HF after one year of hospitalization.
  
  
  RESULTS
  A total of 57 (27%) of the 211 patients died and 115 (67.8%) were readmitted. Mortality was higher in the group with anemia (31.8%) without statistical significance (P=.09), except for refractory HF mortality (P=.013). Predictors of HF mortality included Barthel index (hazard ratio [HR] 0.97, CI 95% 0.96 to 0.98) and serum creatinine at discharge (HR 2.28, 95% CI 1.51 to 3.45). For reentry, the Charlson index (OR 1.16, CI 95% 0.98 to 1.38), treatment with calcium channel blockers (OR 0.29, 95% CI 0.1 to 0.84) and not being treated with digoxin (OR 2.33, CI 95% 1.09 to 4.97), the latter with the greatest influence on readmission for HF (OR 3.07, CI 95% 1.39 to 6.79), along with not being a HF debut (OR 2.8, CI 95% 1.45 to 5.39).
  
  
  CONCLUSIONS
  Anemia is an increased risk of mortality due to refractory HF, but not for readmission within the first year after an acute event.
authors.affiliation: Servicio de Medicina Interna, Hospital Municipal de Badalona, Badalona, Barcelona, España. jgrau@bsa.cat
authors.forename: Jorge
authors.initials: J
authors.lastname: Grau-Amorós
authors.forename: Francesc
authors.initials: F
authors.lastname: Formiga
authors.forename: Oscar
authors.initials: O
authors.lastname: Aramburu
authors.forename: Jesús
authors.initials: J
authors.lastname: Recio-Iglesias
authors.forename: Joan Carles
authors.initials: JC
authors.lastname: Trullàs
authors.forename: Agustín
authors.initials: A
authors.lastname: Urrutia
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000740:Anemia / Q000097:blood / Q000401:mortality*; D015415:Biomarkers / Q000097:blood; D015897:Comorbidity; D016001:Confidence Intervals; D003404:Creatinine / Q000097:blood; D005260:Female; D006333:Heart Failure / Q000097:blood / Q000188:drug therapy / Q000401:mortality*; D006760:Hospitalization / Q000706:statistics & numerical data; D006801:Humans; D008297:Male; D016017:Odds Ratio; D010359:Patient Readmission / Q000706:statistics & numerical data; D011379:Prognosis; D011446:Prospective Studies; D016019:Survival Analysis
chemical_list: D015415:Biomarkers; D003404:Creatinine