title: Feasibility and test-retest reliability of an electroencephalography-based brain mapping system in children with cerebral palsy: a preliminary investigation.
abstract: OBJECTIVE
  To investigate the feasibility and test-retest reliability of a novel electroencephalography (EEG)-based brain mapping system in healthy children and children with cerebral palsy (CP).
  
  
  METHODS
  Correlation statistics.
  
  
  METHODS
  University brain mapping and neurorehabilitation laboratory.
  
  
  METHODS
  A convenience sample of children (N=12; 5 healthy children, mean ± SD, 12.6±0.89y; 7 children with CP, mean ± SD, 9.71±1.1y) participated in the study.
  
  
  METHODS
  Not applicable.
  
  
  METHODS
  Mu band (8-12Hz) power values in event-related spectral perturbation maps during reach and grasp hand movements were repeatedly measured on 2 separate occasions (2h apart). Intraclass correlation coefficient (ICC(1,2)) tests were computed to determine test-retest reliability at the standard level of significance (P<.004). In addition, the feasibility of the system was determined by evaluating potential differences in the cortical activation areas obtained from topographical maps during actual reach and grasp motor tasks between healthy children and children with CP.
  
  
  RESULTS
  The test-retest reliability results showed excellent reliability between the repeated measures, ranging from .93 (P=.000) to .99 (P=.000). Our EEG brain mapping system was capable of distinguishing differences in the cortical activity power (mu band power spectra) between healthy children and children with CP.
  
  
  CONCLUSIONS
  To our knowledge, this study is the first evidence demonstrating the feasibility and reliability of the EEG brain mapping system. Clinically, this system provides important insights into neuroplasticity associated with motor recovery after treatment and can also be used as real-time neurofeedback or noninvasive neuromodulation in the course of neurologic rehabilitation.
authors.affiliation: Department of Physical Therapy, Yonsei University, Wonju City, Kangwon-do, Republic of South Korea.
authors.forename: Nam G
authors.initials: NG
authors.lastname: Lee
authors.forename: Sung K
authors.initials: SK
authors.lastname: Kang
authors.forename: Dong R
authors.initials: DR
authors.lastname: Lee
authors.forename: Han J
authors.initials: HJ
authors.lastname: Hwang
authors.forename: Ji H
authors.initials: JH
authors.lastname: Jung
authors.forename: Joshua Sung H
authors.initials: JS
authors.lastname: You
authors.forename: Chang H
authors.initials: CH
authors.lastname: Im
authors.forename: Dong A
authors.initials: DA
authors.lastname: Kim
authors.forename: Jung A
authors.initials: JA
authors.lastname: Lee
authors.forename: Ki S
authors.initials: KS
authors.lastname: Kim
mesh_terms: D000293:Adolescent; D001132:Arm / Q000502:physiology; D001931:Brain Mapping / Q000379:methods*; D002547:Cerebral Palsy / Q000503:physiopathology* / Q000534:rehabilitation; D002648:Child; D004569:Electroencephalography; D005240:Feasibility Studies; D005260:Female; D006225:Hand / Q000502:physiology; D006801:Humans; D008297:Male; D009068:Movement; D015203:Reproducibility of Results