title: Restless legs syndrome responsive to rasagiline treatment:  a case report.
abstract: We describe a patient with idiopathic restless legs syndrome (iRLS) who was responsive to rasagiline treatment. A 70-year-old woman presented with an 8-year history of iRLS symptoms and a 1-year history of resting tremor. The patient met the UK Parkinson's Disease Society Brain Bank Clinical Diagnostic Criteria (UK Parkinson Disease [PD] Brain Bank criteria) for the diagnosis of idiopathic PD and the criteria of the International Restless Legs Syndrome Study Group for the diagnosis of iRLS. One milligram of rasagiline once daily was started with the diagnosis of early PD as monotherapy. At week 8, the patient was almost iRLS symptoms free. Rasagiline has also been shown to mildly improve PD symptoms. Rasagiline was well tolerated during the follow-up. We suggest that rasagiline could represent a useful therapeutic option in the treatment of iRLS.
authors.affiliation: Department of Neurology, Faculty of Medicine, Bezmi Alem Vakif University, Istanbul, Turkey. gbabacan@hotmail.com
authors.forename: Gulsen
authors.initials: G
authors.lastname: Babacan-Yildiz
authors.forename: Esra
authors.initials: E
authors.lastname: Gursoy
authors.forename: Mehmet
authors.initials: M
authors.lastname: Kolukisa
authors.forename: Arif
authors.initials: A
authors.lastname: Celebi
mesh_terms: D000368:Aged; D005260:Female; D006801:Humans; D007189:Indans / Q000627:therapeutic use*; D012148:Restless Legs Syndrome / Q000175:diagnosis* / Q000188:drug therapy*; D016896:Treatment Outcome
chemical_list: D007189:Indans; C031967:rasagiline