title: Clinical evidence for the superior efficacy of a dentifrice containing 8.0% arginine and calcium carbonate in providing instant and lasting relief of dentin hypersensitivity.
abstract: This paper briefly discusses recent scientific and clinical research validating the effectiveness of a toothpaste containing 8.0% arginine and calcium carbonate, known as Pro-Argin technology, including clinical evidence for the superior efficacy of this toothpaste versus a potassium-based desensitizing toothpaste. It also introduces new clinical data which prove that a toothpaste containing 8.0% arginine and calcium carbonate delivers superior instant and lasting relief of dentin hypersensitivity compared to a toothpaste containing 8% strontium acetate.
authors.affiliation: Colgate-Palmolive Technology Center, Piscataway, New Jersey, USA. Diane_Cummins@colpal.com
authors.forename: D
authors.initials: D
authors.lastname: Cummins
mesh_terms: D000085:Acetates / Q000008:administration & dosage / Q000627:therapeutic use; D001120:Arginine / Q000008:administration & dosage / Q000627:therapeutic use*; D002119:Calcium Carbonate / Q000008:administration & dosage / Q000627:therapeutic use*; D003802:Dentifrices / Q000627:therapeutic use*; D057133:Dentin Desensitizing Agents / Q000627:therapeutic use*; D003807:Dentin Sensitivity / Q000188:drug therapy* / Q000517:prevention & control; D004338:Drug Combinations; D005459:Fluorides / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D010710:Phosphates / Q000627:therapeutic use*; D011188:Potassium / Q000627:therapeutic use; D013324:Strontium / Q000008:administration & dosage / Q000627:therapeutic use; D014100:Toothpastes / Q000627:therapeutic use; D016896:Treatment Outcome
chemical_list: D000085:Acetates; D003802:Dentifrices; D057133:Dentin Desensitizing Agents; D004338:Drug Combinations; D010710:Phosphates; D014100:Toothpastes; C585805:pro-argin; C106741:strontium acetate; D001120:Arginine; D002119:Calcium Carbonate; D005459:Fluorides; D011188:Potassium; D013324:Strontium