title: Nasal floor free mucosal graft for skull base reconstruction and cerebrospinal fluid leak repair.
abstract: OBJECTIVE
  Donor sites for free mucosal grafts for endoscopic endonasal reconstruction of the skull base have traditionally included the middle turbinate, the inferior turbinate, and the nasal septum. The aim of this study was to demonstrate a free mucoperiosteal graft from the nasal cavity floor as a simple alternative donor site for mucosal grafts.
  
  
  METHODS
  In a cadaver study with clinical correlation, we performed endoscopic endonasal harvest of the nasal floor free mucosal graft on two sides of a cadaveric nasal cavity. We also describe the cases of two patients in whom a nasal floor free mucosal graft was used to repair a skull base defect.
  
  
  RESULTS
  The harvest of a nasal floor free mucosal graft is a quick, potentially less morbid method of obtaining free mucosal grafts. In the cases examined, use of this graft carried minimal morbidity and allowed for successful reconstruction of a skull base defect.
  
  
  CONCLUSIONS
  Harvest of nasal floor mucosa is a technically simple method of obtaining free mucoperiosteum for reconstruction of the skull base.
authors.affiliation: Division of Head and Neck Surgery, University of California, Los Angeles, Los Angeles, California, USA.
authors.forename: Jeffrey D
authors.initials: JD
authors.lastname: Suh
authors.forename: Vijay R
authors.initials: VR
authors.lastname: Ramakrishnan
authors.forename: Adam S
authors.initials: AS
authors.lastname: DeConde
mesh_terms: D000328:Adult; D000368:Aged; D002102:Cadaver; D002559:Cerebrospinal Fluid Rhinorrhea / Q000601:surgery*; D005260:Female; D015718:Fibrin Tissue Adhesive; D006490:Hemostatics; D006801:Humans; D007049:Iatrogenic Disease; D008297:Male; D008875:Middle Aged; D009296:Nasal Cavity / Q000601:surgery*; D009297:Nasal Mucosa / Q000637:transplantation*; D019291:Skull Base / Q000293:injuries / Q000601:surgery*
chemical_list: D015718:Fibrin Tissue Adhesive; D006490:Hemostatics