title: Alcohol and adherence to antiretroviral medications: interactive toxicity beliefs among people living with HIV.
abstract: When taken without interruption, antiretroviral therapies (ART) effectively treat HIV infection. Alcohol is a well-known direct and indirect influence on ART adherence. Believing that drinking is harmful while taking ART (interactive toxicity beliefs) is also associated with poor adherence. The current study included 333 people living with HIV who were taking ART and actively using alcohol. Participants were recruited from health care providers and social services in a major southern U.S. city. Results showed that 52% of persons found non-adherent to ART stated that they stopped taking their medications when they were drinking. Multivariate analyses showed that interrupting treatment when drinking was related to current non-adherence, over and above several common correlates of non-adherence including frequency of alcohol use itself. These results confirm and extend past research, indicating an urgent need for medication adherence interventions designed for people living with HIV who drink.
authors.affiliation: Psychology, University of Connecticut, Storrs, CT, USA.
authors.forename: Seth C
authors.initials: SC
authors.lastname: Kalichman
authors.forename: Christina M
authors.initials: CM
authors.lastname: Amaral
authors.forename: Denise
authors.initials: D
authors.lastname: White
authors.forename: Connie
authors.initials: C
authors.lastname: Swetsze
authors.forename: Moira O
authors.initials: MO
authors.lastname: Kalichman
authors.forename: Chauncey
authors.initials: C
authors.lastname: Cherry
authors.forename: Lisa
authors.initials: L
authors.lastname: Eaton
mesh_terms: D000428:Alcohol Drinking / Q000523:psychology; D019380:Anti-HIV Agents / Q000627:therapeutic use*; D015658:HIV Infections / Q000188:drug therapy* / Q000523:psychology; D006801:Humans; D010349:Patient Compliance; D014481:United States
chemical_list: D019380:Anti-HIV Agents