title: Isoquinoline derivatives via stepwise regioselective sp(2) and sp(3) C-H bond functionalizations.
abstract: Efficient and practically attractive stepwise ruthenium- and palladium-catalyzed regioselective C-H bond functionalizations were achieved to produce 4-substituted tetrahydroisoquinoline derivatives featuring various heteroaromatic substructures in moderate to good yields. Both ruthenium- and palladium-based catalytic processes generated nontoxic and easily separable side products.
authors.affiliation: Centre de Recherche en Biotechnologies, BPE 73, Ali Mendjli, Nouvelle Ville, 25000 Constantine, Algeria.
authors.forename: Tarek
authors.initials: T
authors.lastname: Boudiar
authors.forename: Zeyneb
authors.initials: Z
authors.lastname: Sahli
authors.forename: Basker
authors.initials: B
authors.lastname: Sundararaju
authors.forename: Mathieu
authors.initials: M
authors.lastname: Achard
authors.forename: Zahia
authors.initials: Z
authors.lastname: Kabouche
authors.forename: Henri
authors.initials: H
authors.lastname: Doucet
authors.forename: Christian
authors.initials: C
authors.lastname: Bruneau
mesh_terms: D002384:Catalysis; D006860:Hydrogen Bonding; D007546:Isoquinolines / Q000737:chemistry*; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*; D012428:Ruthenium / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D007546:Isoquinolines; D010165:Palladium; D012428:Ruthenium