title: New challenges in detecting, grading, and staging endometrial cancer after uterine morcellation.
abstract: OBJECTIVE
  To evaluate the accuracy in diagnosing endometrial disease after uterine morcellation.
  
  
  METHODS
  Prospective case series.
  
  
  METHODS
  University medical center.
  
  
  METHODS
  Five women undergoing hysterectomy without morcellation because of benign indications and 5 women with endometrial cancer.
  
  
  METHODS
  Uterine specimens were obtained from all 10 study patients. The uteri were sent for pathologic analysis, processed, and fixed according to standard protocols. A single investigator then morcellated all 10 uteri. A single pathologist blinded to specimen group reviewed each specimen.
  
  
  RESULTS
  The pathologist identified endometrial cancer in 4 of 5 specimens of known cancer. The fifth specimen was interpreted as benign despite the presence of grade 1, stage IA endometrial adenocarcinoma. None of the morcellated specimens could be staged.
  
  
  CONCLUSIONS
  The increasing use of uterine morcellation will result in new challenges for gynecologic oncologists secondary to difficulty in detection, and accurate grading and staging of endometrial cancer.
authors.affiliation: Department of Obstetrics and Gynecology, Loyola University Medical Center, Maywood, IL 60153, USA. crivardhunt@gmail.com
authors.forename: Colleen
authors.initials: C
authors.lastname: Rivard
authors.forename: Alia
authors.initials: A
authors.lastname: Salhadar
authors.forename: Kimberly
authors.initials: K
authors.lastname: Kenton
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology*; D000328:Adult; D000368:Aged; D016889:Endometrial Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans; D007044:Hysterectomy / Q000379:methods*; D008875:Middle Aged; D060787:Neoplasm Grading; D009367:Neoplasm Staging; D011446:Prospective Studies; D014599:Uterus / Q000473:pathology* / Q000601:surgery