title: [Segmentation of retinal blood vessels based on centerline extraction].
abstract: The precise estimation of blood vessel centerline and width is a prerequisite condition for the quantitative and visualized diagnosis of blood vessel disease in fundus images. In this paper, a retinal blood vessel segmentation algorithm based on centerline extraction is proposed. According to the characteristics of the fundus image and retinal blood vessels, the image is convoluted with the masks of discrete Gaussian partial derivative kernels. The centerline is determined by differential geometric properties of the blood vessels and the width is also calculated. The precision of our method can reach sub-pixel level with a fast computation speed. The experiments on several kinds of fundus images showed that the method worked quickly and accurately.
authors.affiliation: College of Mechanical & Electrical Engineering, Nanjing University of Aeronautics and Astronautics, Nanjing 210016, China. zlinlinz@163.com
authors.forename: Lin
authors.initials: L
authors.lastname: Zhou
authors.forename: Jianxin
authors.initials: J
authors.lastname: Shen
authors.forename: Wenhe
authors.initials: W
authors.lastname: Liao
authors.forename: Yuliang
authors.initials: Y
authors.lastname: Wang
mesh_terms: D000465:Algorithms; D005654:Fundus Oculi; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D012171:Retinal Vessels / Q000033:anatomy & histology*