title: Lipid rafts, caveolae and GPI-linked proteins.
abstract: Lipid rafts and caveolae are specialized membrane microdomains enriched in sphingolipids and cholesterol. They function in a variety of cellular processes including but not limited to endocytosis, transcytosis, signal transduction and receptor recycling. Here, we outline the similarities and differences between lipid rafts and caveolae as well as discuss important components and functions of each.
authors.affiliation: University of Kentucky, Lexington, KY, USA.
authors.forename: Valerie L
authors.initials: VL
authors.lastname: Reeves
authors.forename: Candice M
authors.initials: CM
authors.lastname: Thomas
authors.forename: Eric J
authors.initials: EJ
authors.lastname: Smart
mesh_terms: D000818:Animals; D021941:Caveolae / Q000378:metabolism; D002784:Cholesterol / Q000378:metabolism; D058851:GPI-Linked Proteins / Q000378:metabolism; D006801:Humans; D021962:Membrane Microdomains / Q000378:metabolism
chemical_list: D058851:GPI-Linked Proteins; D002784:Cholesterol