title: Vitamin D status in women with pelvic floor disorder symptoms.
abstract: OBJECTIVE
  Our aim was to characterize the relationship between 25-hydroxyvitamin D [25(OH)D] status with pelvic floor symptom distress and impact on quality of life.
  
  
  METHODS
  A retrospective chart review was performed in women with a 25(OH)D level drawn within 1 year of their gynecology/urogynecology visit. Validated questionnaires including the Colorectal-Anal Distress Inventory (CRADI)-8 and Incontinence Impact Questionnaire (IIQ-7) were used. Multivariate analyses characterized pelvic floor disorder (PFD) symptom differences among women by vitamin D status.
  
  
  RESULTS
  We studied 394 women. Mean ± standard deviation (SD) 25(OH)D levels were higher in women without than with PFD symptoms (35.0 ± 14.1 and 29.3 ± 11.5 ng/ml, respectively (p < 0.001)]. The prevalence of vitamin D insufficiency was 51% (136/268). CRADI-8 and IIQ-7 scores were higher among women with vitamin D insufficiency (p = 0.03 and p = 0.001, respectively). Higher IIQ-7 scores were independently associated with vitamin D insufficiency (p < 0.001).
  
  
  CONCLUSIONS
  Insufficient vitamin D is associated with increased colorectal symptom distress and greater impact of urinary incontinence on quality of life.
authors.affiliation: Division of Urogynecology and Pelvic Reconstructive Surgery, Department of Obstetrics and Gynecology, University of Alabama at Birmingham, 619 19th Street South, 176-F, Suite 10382, Birmingham, AL 35249, USA. cautry@uabmc.edu
authors.forename: Candace Y
authors.initials: CY
authors.lastname: Parker-Autry
authors.forename: Alayne D
authors.initials: AD
authors.lastname: Markland
authors.forename: Alicia C
authors.initials: AC
authors.lastname: Ballard
authors.forename: Deidra
authors.initials: D
authors.lastname: Downs-Gunn
authors.forename: Holly E
authors.initials: HE
authors.lastname: Richter
mesh_terms: D005260:Female; D006801:Humans; D008875:Middle Aged; D059952:Pelvic Floor Disorders / Q000097:blood*; D011788:Quality of Life; D014807:Vitamin D / Q000031:analogs & derivatives* / Q000097:blood; D014808:Vitamin D Deficiency / Q000150:complications
chemical_list: D014807:Vitamin D; C104450:25-hydroxyvitamin D