title: NHC-catalysed diastereoselective synthesis of multifunctionalised piperidines via cascade reaction of enals with azalactones.
abstract: NHC-catalysed azalactone ring-opening and piperidine ring-closing cascade with α,β-unsaturated aldehydes (enals) in a one-pot operation is reported. The present reaction cascade offers a convenient method for a highly diastereoselective synthesis of multifunctionalised piperidines in excellent yields under mild conditions.
authors.affiliation: Green Synthesis Lab, Department of Chemistry, University of Allahabad, Allahabad-211002, India.
authors.forename: Atul K
authors.initials: AK
authors.lastname: Singh
authors.forename: Ruchi
authors.initials: R
authors.lastname: Chawla
authors.forename: Ankita
authors.initials: A
authors.lastname: Rai
authors.forename: Lal Dhar S
authors.initials: LD
authors.lastname: Yadav