title: An update on diastolic dysfunction.
abstract: Diastolic dysfunction refers to abnormal diastolic filling properties of the left ventricle regardless of whether systolic function is normal or the patient has symptoms. Diastolic heart failure (HF), or more accurately, HF with preserved systolic function, is a distinct clinical entity characterized by the presence of the triad of impaired diastolic function, normal systolic function (left ventricular ejection fraction > 50%), and symptoms of HF. Patients with HF with preserved systolic function are frequently symptomatic from both acute and chronic elevations in left ventricular end-diastolic pressure and/or left atrial pressure.
authors.affiliation: Department of Medicine, Division of Cardiology, New York Medical College/Westchester Medical Center, Valhalla, NY, USA.
authors.forename: Gregg M
authors.initials: GM
authors.lastname: Lanier
authors.forename: Prashant
authors.initials: P
authors.lastname: Vaishnava
authors.forename: Constantine E
authors.initials: CE
authors.lastname: Kosmas
authors.forename: Gabriel
authors.initials: G
authors.lastname: Wagman
authors.forename: Robert
authors.initials: R
authors.lastname: Hiensch
authors.forename: Timothy J
authors.initials: TJ
authors.lastname: Vittorio
mesh_terms: D004232:Diuretics / Q000627:therapeutic use; D005544:Forecasting; D054144:Heart Failure, Diastolic / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D006801:Humans; D008875:Middle Aged; D011379:Prognosis; D018487:Ventricular Dysfunction, Left / Q000175:diagnosis / Q000209:etiology / Q000628:therapy
chemical_list: D004232:Diuretics