title: Foldable iris-fixated intraocular lens implantation in children.
abstract: OBJECTIVE
  To describe the results of foldable iris-fixated intraocular lens (IOL) implantation in children.
  
  
  METHODS
  Children with high bilateral or unilateral myopia who were intolerant of spectacle or contact lens correction were implanted with an iris-fixated foldable IOL and prospectively followed. We measured pre- and postoperative visual acuity, refraction, endothelial cell density (ECD) and National Eye Institute Visual Functioning Questionnaire-25.
  
  
  RESULTS
  Eleven eyes of six children were implanted. Indications were high bilateral myopia in children with comorbid neurobehavioural disorders, high anisometropia and high myopic astigmatism. Mean preoperative spherical equivalent (SE) refraction was -14.6 dioptres (D)±4.2 SD. Mean follow-up was 15 months. Postoperative SE refraction was -2.40 D±2.40 SD. Corrected distance visual acuity (CDVA) improved from mean logMAR 0.84±0.4 SD to postoperative 0.67±0.34 SD (p=0.005). CDVA was reduced because of coexistent ocular disorders and amblyopia. Vision-related quality of life (QOL) measures improved significantly. There were no intraoperative or postoperative serious complications.
  
  
  CONCLUSIONS
  Foldable iris-fixated IOL insertion can give a significant improvement in vision and in vision-related QOL in a subset of paediatric patients with special refractive needs who are intolerant to conventional treatment. Long-term follow-up is required for monitoring of ECD.
authors.affiliation: Department of Ophthalmology, Children's University Hospital, Dublin, Ireland.
authors.forename: Andrea
authors.initials: A
authors.lastname: Ryan
authors.forename: Claire
authors.initials: C
authors.lastname: Hartnett
authors.forename: Bernadette
authors.initials: B
authors.lastname: Lanigan
authors.forename: Michael
authors.initials: M
authors.lastname: O'Keefe
mesh_terms: D000293:Adolescent; D002452:Cell Count; D002648:Child; D004728:Endothelium, Corneal / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007498:Iris / Q000601:surgery*; D019654:Lens Implantation, Intraocular / Q000379:methods*; D008297:Male; D047728:Myopia, Degenerative / Q000503:physiopathology / Q000601:surgery*; D054120:Phakic Intraocular Lenses; D011446:Prospective Studies; D011474:Prosthesis Design; D011788:Quality of Life; D012029:Refraction, Ocular / Q000502:physiology; D018434:Sickness Impact Profile; D011795:Surveys and Questionnaires; D016896:Treatment Outcome; D014792:Visual Acuity / Q000502:physiology