title: Atypical presentation of pediatric mixed germ cell tumors in the sellar-suprasellar region.
abstract: Intracranial germ cell tumors constitute a unique group of tumors, more often reported from the Asian region. Amongst them, the non-germinomatous variety occurs with a lesser frequency than the germinomatous variety. We report two children with mixed germ cell tumors with unusual clinical presentations: Central diabetes insipidus and recent-onset oculomotor palsy mimicking pituitary apoplexy. Unlike in adults, suprasellar lesions with a pituitary apoplexy-like picture in the pediatric age group may suggest a possibility of a mixed germ cell tumor.
authors.affiliation: Department of Neurosurgery, Sri Sathya Sai Institute of Higher Medical Sciences, Bangalore, India. sunilvf@gmail.com
authors.forename: Sunil V
authors.initials: SV
authors.lastname: Furtado
authors.forename: Sumit
authors.initials: S
authors.lastname: Thakar
authors.forename: Nandita
authors.initials: N
authors.lastname: Ghosal
authors.forename: Alangar S
authors.initials: AS
authors.lastname: Hegde
mesh_terms: D000293:Adolescent; D002648:Child; D020790:Diabetes Insipidus, Neurogenic / Q000209:etiology; D005260:Female; D018237:Germinoma / Q000150:complications / Q000000981:diagnostic imaging / Q000378:metabolism / Q000473:pathology*; D006728:Hormones / Q000378:metabolism; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009373:Neoplasms, Germ Cell and Embryonal / Q000150:complications / Q000000981:diagnostic imaging / Q000378:metabolism / Q000473:pathology*; D010899:Pituitary Apoplexy / Q000209:etiology; D012658:Sella Turcica / Q000000981:diagnostic imaging / Q000473:pathology*; D014057:Tomography, X-Ray Computed
chemical_list: D006728:Hormones