title: Epicardial mass causing cardiac compression: an unusual involvement in lymphomatoid granulomatosis.
abstract: Lymphomatoid granulomatosis is a rare, diffuse, large B-cell lymphoma that is positive for Epstein-Barr virus. A multiorgan process, it manifests itself chiefly in the lungs but can also affect the skin, nervous system, and kidneys. Cardiac involvement and pericardial effusion are very unusual. We report the case of a 62-year-old man with lymphomatoid granulomatosis involving the heart and lungs. Diagnosis was confirmed with wedge biopsy at pericardiotomy, and the patient was treated with cyclophosphamide, prednisolone, and vincristine. Although the patient was still symptomatic at 6-month follow-up, he was in partial remission with improved functional capacity.
authors.affiliation: Department of Cardiology, Faculty of Medicine, University of Karaelmas, 67600 Zonguldak, Turkey. turgutkarabag@yahoo.com
authors.forename: Turgut
authors.initials: T
authors.lastname: Karabag
authors.forename: Mustafa
authors.initials: M
authors.lastname: Aydin
authors.forename: Figen
authors.initials: F
authors.lastname: Barut
authors.forename: Mustafa
authors.initials: M
authors.lastname: Buyukates
authors.forename: Sait Mesut
authors.initials: SM
authors.lastname: Dogan
authors.forename: Oguzhan
authors.initials: O
authors.lastname: Celik
authors.forename: Muhammet Rasit
authors.initials: MR
authors.lastname: Sayin
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D014408:Biomarkers, Tumor / Q000032:analysis; D001706:Biopsy; D004452:Echocardiography; D006338:Heart Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D006801:Humans; D007150:Immunohistochemistry; D008175:Lung Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D008230:Lymphomatoid Granulomatosis / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D010490:Pericardial Effusion / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery; D010492:Pericardiectomy; D010496:Pericardium / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D011237:Predictive Value of Tests; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D014408:Biomarkers, Tumor