title: Revisiting the histopathologic spectrum of congenital pulmonary developmental disorders.
abstract: A retrospective analysis of lobectomy, pneumonectomy, cystectomy specimens (10 years) and stillbirth/neonatal autopsies (5 years) was carried out to analyze the histologic spectrum of congenital pulmonary developmental disorders/malformations. The autopsy data was analyzed to identify the lesions that are more diffuse and not amenable to surgical management. A total of 166 cases of pulmonary developmental disorders/ malformation were found. Out of 2,155 stillbirth/neonatal autopsies, there were 105 cases of pulmonary hypoplasia, 2 cases of congenital pulmonary lymphangiectasis, 2 cases of extralobar sequestration, and 3 cases of congenital pulmonary airway malformation (CPAM). Among the surgical specimens, there were 21 cases of CPAM, 11 cases of intralobar sequestration, 5 cases of congenital lobar emphysema and 17 cases of bronchogenic cyst. All these malformations have been described in reference to the latest updated classification of developmental disorders/malformations.
authors.affiliation: Post-Graduate Institute of Medical Education and Research, Department of Histopathology, Chandigarh, India. kirtigupta10@yahoo.co.in
authors.forename: Kirti
authors.initials: K
authors.lastname: Gupta
authors.forename: Ashim
authors.initials: A
authors.lastname: Das
authors.forename: Prema
authors.initials: P
authors.lastname: Menon
authors.forename: Nandita
authors.initials: N
authors.lastname: Kakkar
authors.forename: K L N
authors.initials: KL
authors.lastname: Rao
authors.forename: Kusum
authors.initials: K
authors.lastname: Joshi
mesh_terms: D001344:Autopsy; D006801:Humans; D008168:Lung / Q000002:abnormalities*; D008171:Lung Diseases / Q000151:congenital*; D012189:Retrospective Studies