title: A novel synthetic strategy for monosubstituted cyclodextrin derivatives.
abstract: A first solid phase approach to obtain monosubstituted CD conjugates to different labels has been developed. A new solid support has been designed to get a variety of C-6 monofunctionalized CDs (α, β, MeβCD and HPβCD) covalently linked through a phosphodiester bridge to different labels, in highly pure form and under very mild detachment conditions.
authors.affiliation: Dipartimento di Scienze Chimiche, Università degli Studi di Napoli Federico II, Complesso Universitario di Monte S. Angelo, via Cintia, 4, I-80126 Napoli, Italy. difabio@unina.it
authors.forename: Giovanni
authors.initials: G
authors.lastname: Di Fabio
authors.forename: Gaetano
authors.initials: G
authors.lastname: Malgieri
authors.forename: Carla
authors.initials: C
authors.lastname: Isernia
authors.forename: Jennifer
authors.initials: J
authors.lastname: D'Onofrio
authors.forename: Maria
authors.initials: M
authors.lastname: Gaglione
authors.forename: Anna
authors.initials: A
authors.lastname: Messere
authors.forename: Armando
authors.initials: A
authors.lastname: Zarrelli
authors.forename: Lorenzo
authors.initials: L
authors.lastname: De Napoli
mesh_terms: D003505:Cyclodextrins / Q000138:chemical synthesis / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D009943:Organophosphorus Compounds / Q000737:chemistry; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
chemical_list: D003505:Cyclodextrins; D009943:Organophosphorus Compounds; C434331:phosphoramidite