title: [Assessment of health-related quality of life in cancer outpatients treated with chemotherapy].
abstract: OBJECTIVE
  Few studies have been conducted to elucidate the health-related quality of life(HR-QOL)of cancer outpatients treated with chemotherapy. In this study, we attempted to determine the physical and psychological distress of cancer outpatients treated with chemotherapy.
  
  
  METHODS
  Two-hundred and ninety-six outpatients with various malignancies, including malignant lymphoma, and esophageal, gastric, pancreatic, colon, lung, breast, ovarian, uterine and skin cancers, were investigated using the Japanese version of the M. D. Anderson symptom inventory from March through June 2010 in Tokyo Medical University Hospital.
  
  
  RESULTS
  The results of the survey questionnaire indicated that 59 patients suffered from fatigue, 56 experienced numbness or tingling, 48 felt drowsy, 39 had low moods, 40 felt distressed, 38 had no appetite, 38 had dry mouth, 37 were in pain, 37 had disturbed sleep, 31 had shortness of breath, 24 had nausea, 17 suffered from vomiting, and 13 patients had memory problems. Furthermore, these symptoms interfered with work(65 patients), walking(56 patients), mood(52 patients), life enjoyment(49 patients), general activity(49 patients), and relationships with other people(42 patients). Medications prescribed for HR-QOL control were non-steroidal anti-inflammatory drugs(93 patients), morphine(32 patients), and adjuvant analgesics(47 patients).
  
  
  CONCLUSIONS
  The present findings may help in the development of management strategies for physical and psychological distress, and improve HR-QOL of cancer outpatients treated with chemotherapy.
authors.affiliation: Dept. of Clinical Oncology, Tokyo Medical University Hospital, Tokyo, Japan.
authors.forename: Tomohisa
authors.initials: T
authors.lastname: Yokoyama
authors.forename: Yui
authors.initials: Y
authors.lastname: Kurokawa
authors.forename: Rinako
authors.initials: R
authors.lastname: Kani
authors.forename: Emiko
authors.initials: E
authors.lastname: Takatori
authors.forename: Shoko
authors.initials: S
authors.lastname: Nokiguchi
authors.forename: Yasuyo
authors.initials: Y
authors.lastname: Suzuki
authors.forename: Hanayo
authors.initials: H
authors.lastname: Kawashima
authors.forename: Michiko
authors.initials: M
authors.lastname: Uenishi
authors.forename: Miyuki
authors.initials: M
authors.lastname: Kawashima
authors.forename: Youichi
authors.initials: Y
authors.lastname: Osato
authors.forename: Hironobu
authors.initials: H
authors.lastname: Miyamatsu
authors.forename: Atsushi
authors.initials: A
authors.lastname: Sofuni
authors.forename: Takao
authors.initials: T
authors.lastname: Itoi
authors.forename: Norihiko
authors.initials: N
authors.lastname: Ikeda
authors.forename: Kazuma
authors.initials: K
authors.lastname: Ohyashiki
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000970:Antineoplastic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D009369:Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000523:psychology; D010045:Outpatients; D011788:Quality of Life; D011795:Surveys and Questionnaires; D055815:Young Adult
chemical_list: D000970:Antineoplastic Agents