title: Palladium-catalyzed dehydrogenative β'-functionalization of β-keto esters with indoles at room temperature.
abstract: The dehydrogenative β'-functionalization of α-substituted β-keto esters with indoles proceeds with high regioselectivities (C3-selective for the indole partner and β'-selective for the β-keto ester) and good yields under mild palladium catalysis at room temperature with a variety of oxidants. Two possible mechanisms involving either late or early involvement of indole are presented.
authors.affiliation: Department of Chemistry and NanoScience Center, University of Jyväskylä, FI-40014 JYU, Finland.
authors.forename: Mikko V
authors.initials: MV
authors.lastname: Leskinen
authors.forename: Kai-Tai
authors.initials: KT
authors.lastname: Yip
authors.forename: Arto
authors.initials: A
authors.lastname: Valkonen
authors.forename: Petri M
authors.initials: PM
authors.lastname: Pihko