title: Colonization of the oral cavity by probiotic bacteria.
abstract: The aim of this study was to investigate if three probiotic bacteria present in the milk product Cultura Dofilus® naturell could be detected in saliva and on oral mucosal surfaces, and if they colonized dental surfaces in situ in 8 caries-inactive individuals after 8 daily exposures to the milk product for up to 3 days. Bacteria were identified by fluorescence in situ hybridization and confocal laser scanning microscopy. While probiotic bacteria were present sporadically in the oral cavity on mucosal surfaces and in saliva after 3 days of frequent use of the probiotic milk, they were not detected on dental surfaces. Probiotic bacteria may thus contribute to general oral health, but their potential role in biofilm-induced dental diseases remains unclear.
authors.affiliation: School of Dentistry, Aarhus Faculty of Health Sciences, Aarhus University, Aarhus, Denmark.
authors.forename: I
authors.initials: I
authors.lastname: Ravn
authors.forename: I
authors.initials: I
authors.lastname: Dige
authors.forename: R L
authors.initials: RL
authors.lastname: Meyer
authors.forename: B
authors.initials: B
authors.lastname: Nyvad
mesh_terms: D000328:Adult; D018441:Biofilms; D003611:Dairy Products / Q000382:microbiology; D003773:Dental Plaque / Q000382:microbiology; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D007778:Lactobacillus / Q000302:isolation & purification*; D018613:Microscopy, Confocal; D009061:Mouth Mucosa / Q000382:microbiology*; D019936:Probiotics; D012463:Saliva / Q000382:microbiology*; D055815:Young Adult