title: DNA transport and delivery in thermal gradients near optofluidic resonators.
abstract: Heat generation and its impact on DNA transport in the vicinity of an optofluidic silicon photonic crystal resonator are studied theoretically and experimentally. The temperature rise is measured to be as high as 57 K for 10 mW of input power. The resulting optical trapping and biomolecular sensing properties of these devices are shown to be strongly affected by the combination of buoyancy driven flow and thermophoresis. Specifically, the region around the electromagnetic hot spot is depleted in biomolecules because of a high free energy barrier.
authors.affiliation: School of Applied and Engineering Physics, Cornell University, Ithaca, New York 14853, USA.
authors.forename: Xavier
authors.initials: X
authors.lastname: Serey
authors.forename: Sudeep
authors.initials: S
authors.lastname: Mandal
authors.forename: Yih-Fan
authors.initials: YF
authors.lastname: Chen
authors.forename: David
authors.initials: D
authors.lastname: Erickson
mesh_terms: D015374:Biosensing Techniques / Q000379:methods; D003460:Crystallization; D004247:DNA / Q000737:chemistry*; D006358:Hot Temperature; D044085:Microfluidics / Q000379:methods; D036103:Nanotechnology / Q000379:methods*; D055096:Optical Devices; D055095:Optics and Photonics / Q000379:methods*; D012825:Silicon / Q000737:chemistry
chemical_list: D004247:DNA; D012825:Silicon