title: Reversible posterior leukoencephalopathy in a venomous snake (Bothrops asper) bite victim.
abstract: An 18-year-old man developed posterior reversible leukoencephalopaty after being bitten by a venomous snake (Bothrops asper). It is possible that this previously unrecognized neurological complication of snake bite envenoming occurred as the result of endothelial dysfunction induced by the venom of the offending snake. This pathogenetic mechanism has also been implicated as the cause of cerebral infarctions in snake bite victims. Alternatively, the leukoencephalopathy might have been a complication of antivenom therapy.
authors.affiliation: Intensive Care Unit, Hospital de Infectología Daniel Rodríguez Maridueña, Ministerio de Salud Pública, Guayaquil, Ecuador. drmiguel_delgado@yahoo.com
authors.forename: Miguel E
authors.initials: ME
authors.lastname: Delgado
authors.forename: Oscar H
authors.initials: OH
authors.lastname: Del Brutto
mesh_terms: D000293:Adolescent; D000818:Animals; D000997:Antivenins / Q000008:administration & dosage*; D017837:Bothrops; D004484:Ecuador; D006801:Humans; D056784:Leukoencephalopathies / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D008297:Male; D012909:Snake Bites / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D014057:Tomography, X-Ray Computed / Q000379:methods; D016896:Treatment Outcome
chemical_list: D000997:Antivenins