title: Paper-based electrochemical sensing platform with integral battery and electrochromic read-out.
abstract: We report a battery-powered, microelectrochemical sensing platform that reports its output using an electrochromic display. The platform is fabricated based on paper fluidics and uses a Prussian blue spot electrodeposited on an indium-doped tin oxide thin film as the electrochromic indicator. The integrated metal/air battery powers both the electrochemical sensor and the electrochromic read-out, which are in electrical contact via a paper reservoir. The sample activates the battery and the presence of analyte in the sample initiates the color change of the Prussian blue spot. The entire system is assembled on the lab bench, without the need for cleanroom facilities. The applicability of the device to point-of-care sensing is demonstrated by qualitative detection of 0.1 mM glucose and H(2)O(2) in artificial urine samples.
authors.affiliation: Department of Chemistry and Biochemistry, Center for Electrochemistry, The University of Texas at Austin, 1 University Station, A5300, Austin, Texas 78712-0165, USA.
authors.forename: Hong
authors.initials: H
authors.lastname: Liu
authors.forename: Richard M
authors.initials: RM
authors.lastname: Crooks
mesh_terms: D011211:Electric Power Supplies; D055664:Electrochemical Techniques; D005295:Ferrocyanides / Q000737:chemistry; D005947:Glucose / Q000032:analysis; D006861:Hydrogen Peroxide / Q000652:urine; D010209:Paper; D019095:Point-of-Care Systems; D017971:Tin Compounds / Q000737:chemistry
chemical_list: D005295:Ferrocyanides; D017971:Tin Compounds; C109984:indium tin oxide; D006861:Hydrogen Peroxide; D005947:Glucose; C000170:ferric ferrocyanide