title: Gold nanoparticles developed in sol-gel derived apatite--bioactive glass composites.
abstract: The study is focussed on synthesis and characterisation of a new sol-gel derived composite system consisting of nanocrystalline apatite, bioactive glass and gold nanoparticles, which are of interest both for regenerative medicine and for specific medical applications of the releasable gold nanoparticles. Samples dried at 110°C and then heat treated for 30 min at 300 and 500°C were investigated by thermal analysis (DTA/TG), X-ray diffraction (XRD), UV-VIS-NIR, Fourier Transform Infrared (FTIR) spectroscopy, X-ray Photoelectron(XPS) spectroscopy, Scanning Electron Microscopy (SEM) and Transmission Electron Microscopy (TEM). Gold nanoparticles and nanocrystalline apatite are developed already after heat treatment at 300°C. XPS analysis clearly revealed the presence of both metallic and ionic gold species. The development of gold nanoparticles was evidenced by UV-VIS-NIR and TEM analysis, and their size increased from few nanometers to 25 nm by increasing the treatment temperature from 300 to 500°C. The bioactivity of the samples immersed in simulated body fluid was demonstrated by XRD and SEM results.
authors.affiliation: Faculty of Physics & Institute of Interdisciplinary Research in Bio-Nano-Sciences, Babes Bolyai University, 400084 Cluj-Napoca, Romania. simons@phys.ubbcluj.ro
authors.forename: S
authors.initials: S
authors.lastname: Simon
authors.forename: R
authors.initials: R
authors.lastname: Ciceo-Lucacel
authors.forename: T
authors.initials: T
authors.lastname: Radu
authors.forename: L
authors.initials: L
authors.lastname: Baia
authors.forename: O
authors.initials: O
authors.lastname: Ponta
authors.forename: A
authors.initials: A
authors.lastname: Iepure
authors.forename: V
authors.initials: V
authors.lastname: Simon
mesh_terms: D001031:Apatites / Q000737:chemistry / Q000494:pharmacology*; D011232:Chemical Precipitation; D004055:Differential Thermal Analysis; D005898:Glass / Q000737:chemistry*; D006046:Gold / Q000737:chemistry*; D053768:Metal Nanoparticles / Q000737:chemistry*; D046529:Microscopy, Electron, Transmission; D055616:Microtechnology; D036103:Nanotechnology; D044367:Phase Transition; D011108:Polymers / Q000737:chemistry; D013056:Spectrophotometry, Ultraviolet; D019265:Spectroscopy, Near-Infrared; D013696:Temperature; D014961:X-Ray Diffraction
chemical_list: D001031:Apatites; D011108:Polymers; D006046:Gold