title: Focus on methodology: salivary bioscience and research on adolescence: an integrated perspective.
abstract: The characterization of the salivary proteome and advances in biotechnology create an opportunity for developmental scientists to measure multi-level components of biological systems in oral fluids and identify relationships with developmental processes and behavioral and social forces. The implications for developmental science are profound because from a single oral fluid specimen, information can be obtained about a broad array of biological systems and the genetic polymorphisms related to their function. The purpose of this review is to provide a conceptual and tactical roadmap for investigators interested in integrating these measurement tools into research on adolescent health and development.
authors.affiliation: Center for Interdisciplinary Salivary Bioscience Research, Johns Hopkins University, Baltimore, MD 21205-2110, USA. dgrange2@jhu.edu
authors.forename: Douglas A
authors.initials: DA
authors.lastname: Granger
authors.forename: Christine K
authors.initials: CK
authors.lastname: Fortunato
authors.forename: Emilie K
authors.initials: EK
authors.lastname: Beltzer
authors.forename: Marta
authors.initials: M
authors.lastname: Virag
authors.forename: Melissa A
authors.initials: MA
authors.lastname: Bright
authors.forename: Dorothée
authors.initials: D
authors.lastname: Out
mesh_terms: D000293:Adolescent / Q000502:physiology*; D041923:Adolescent Development / Q000502:physiology; D002648:Child; D002940:Circadian Rhythm / Q000502:physiology; D005260:Female; D006801:Humans; D008297:Male; D011110:Polymorphism, Genetic; D012463:Saliva / Q000737:chemistry* / Q000502:physiology; D013315:Stress, Psychological / Q000503:physiopathology