title: [Current status of research in breast cancer screening in Spain: implications for prevention].
abstract: OBJECTIVE
  The consolidation of breast cancer screening programs, with full coverage of the target population in all Spanish regions, has encouraged the beginning of a joint research strategy. This strategy aims to improve the effectiveness of breast cancer screening by gathering information from distinct screening programs.
  
  
  METHODS
  A retrospective cohort with information on over 1.5 million screened women was constructed to evaluate risk factors for a false-positive result. The impact of the change from digital mammography to screen-film mammography was evaluated, while results for interval cancers and false negatives are currently being studied.
  
  
  RESULTS
  The results are highly useful from the perspective of public health, as they can be used to identify and improve the information provided to women with a higher risk of experiencing an adverse effect. These results will also be helpful to identify screening program-related characteristics and women's personal characteristics, which will allow better prevention strategies to be developed.
  
  
  CONCLUSIONS
  The results obtained will be included in mathematical models currently under development to evaluate the efficiency of breast cancer screening. These models could be highly useful to provide information and guide clinical and health policy decisions on cancer prevention and control.
authors.affiliation: Servei d'Epidemiologia i Avaluació, Hospital del Mar-Parc de Salut Mar, Barcelona, España. msalaserra@parcdesalutmar.cat
authors.forename: María
authors.initials: M
authors.lastname: Sala
authors.forename: Dolores
authors.initials: D
authors.lastname: Salas
authors.forename: Raquel
authors.initials: R
authors.lastname: Zubizarreta
authors.forename: Nieves
authors.initials: N
authors.lastname: Ascunce
authors.forename: Montse
authors.initials: M
authors.lastname: Rué
authors.forename: Xavier
authors.initials: X
authors.lastname: Castells
mesh_terms: D000368:Aged; D014408:Biomarkers, Tumor; D001943:Breast Neoplasms / Q000737:chemistry / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000517:prevention & control*; D003198:Computer Simulation; D016208:Databases, Factual; D055088:Early Detection of Cancer / Q000706:statistics & numerical data*; D005188:False Negative Reactions; D005189:False Positive Reactions; D005260:Female; D006293:Health Promotion / Q000458:organization & administration / Q000706:statistics & numerical data*; D006801:Humans; D008327:Mammography / Q000379:methods / Q000706:statistics & numerical data; D008875:Middle Aged; D008962:Models, Theoretical; D017410:Practice Guidelines as Topic; D011856:Radiographic Image Enhancement; D012107:Research Design; D012189:Retrospective Studies; D012307:Risk Factors; D013030:Spain / Q000453:epidemiology; D057170:Translational Research, Biomedical
chemical_list: D014408:Biomarkers, Tumor