title: Highly efficient heterogeneous gold-catalyzed direct synthesis of tertiary and secondary amines from alcohols and urea.
abstract: Urea, the white gold: The efficient synthesis of tertiary and secondary amines is achieved by heterogeneous gold-catalyzed direct amination of stoichiometric alcohols with urea in good to excellent yields. Via a hydrogen autotransfer pathway, the reactions of primary alcohols with urea give tertiary amines exclusively, while secondary alcohols selectively afford secondary amines.
authors.affiliation: Department of Chemistry, Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, Fudan University, Shanghai, PR China.
authors.forename: Lin
authors.initials: L
authors.lastname: He
authors.forename: Yue
authors.initials: Y
authors.lastname: Qian
authors.forename: Ran-Sheng
authors.initials: RS
authors.lastname: Ding
authors.forename: Yong-Mei
authors.initials: YM
authors.lastname: Liu
authors.forename: He-Yong
authors.initials: HY
authors.lastname: He
authors.forename: Kang-Nian
authors.initials: KN
authors.lastname: Fan
authors.forename: Yong
authors.initials: Y
authors.lastname: Cao
mesh_terms: D000438:Alcohols / Q000737:chemistry*; D000588:Amines / Q000138:chemical synthesis* / Q000737:chemistry*; D002384:Catalysis; D060326:Chemistry Techniques, Synthetic / Q000379:methods*; D006046:Gold / Q000737:chemistry*; D014508:Urea / Q000737:chemistry*
chemical_list: D000438:Alcohols; D000588:Amines; D006046:Gold; D014508:Urea