title: [Botulinum toxin versus sacral neuromodulation for idiopathic detrusor overactivity].
abstract: Idiopathic detrusor overactivity (motory urge) negatively affects the live of patients. Conservative treatment is not always effective and has multiple side effects. Sacral neuromodulation is a second line therapy for the treatment of idiopatic detrusor overactivity. Over the last decade, botulinum toxin injections have been increasingly used as alternative although there are only few randomized studies. Goal of this review is to compare efficiacy, safety and cost effectiveness of both methods.
authors.affiliation: Klinik und Poliklinik für Urologie, Universitätsmedizin Mainz, Langenbeckstraße 1, 55122 Mainz, Deutschland. wolfgang.leicht@unimedizin-mainz.de
authors.forename: W
authors.initials: W
authors.lastname: Leicht
authors.forename: C
authors.initials: C
authors.lastname: Hampel
authors.forename: J
authors.initials: J
authors.lastname: Thüroff
mesh_terms: D000283:Administration, Intravesical; D019274:Botulinum Toxins, Type A / Q000008:administration & dosage*; D004599:Electric Stimulation Therapy / Q000295:instrumentation / Q000379:methods*; D004567:Electrodes, Implanted; D006801:Humans; D008160:Lumbosacral Plexus / Q000503:physiopathology*; D017773:Pelvic Floor / Q000294:innervation; D012648:Self Care; D014521:Urethra / Q000294:innervation; D001743:Urinary Bladder / Q000294:innervation; D053201:Urinary Bladder, Overactive / Q000503:physiopathology / Q000628:therapy*; D014546:Urinary Catheterization
chemical_list: D019274:Botulinum Toxins, Type A