title: Contactless NMR spectroscopy on a chip.
abstract: Inductively coupled planar resonators offer convenient integration of high-resolution NMR spectroscopy with microfluidic lab-on-a-chip devices. Planar spiral resonators are fabricated lithographically either by gold electroplating or by etching Cu laminated with polyimide. Their performance is characterized by NMR imaging as well as spectroscopy. A single-scan limit of detection LOD(t) = 0.95 nmol s(1/2) was obtained from sample volumes around 1 μL. The sensitivity of this approach is similar to that obtained by microstripline and microslot probes.
authors.affiliation: Department of Mechanical and Aeropspace Engineering, University of Virginia, Charlottesville, Virginia 22904, United States.
authors.forename: Herbert
authors.initials: H
authors.lastname: Ryan
authors.forename: Suk-Heung
authors.initials: SH
authors.lastname: Song
authors.forename: Anja
authors.initials: A
authors.lastname: Zaß
authors.forename: Jan
authors.initials: J
authors.lastname: Korvink
authors.forename: Marcel
authors.initials: M
authors.lastname: Utz
mesh_terms: D057230:Limit of Detection; D009682:Magnetic Resonance Spectroscopy; D046210:Microfluidic Analytical Techniques / Q000295:instrumentation / Q000379:methods