title: Haworforbins A-C, new phenolics from Haworthia cymbiformis.
abstract: Two new isocoumarin glucosides, haworforbins A (1) and B (2), and a new chromone, haworforbin C (3), have been isolated from Haworthia cymbiformis. Their structures and absolute configurations were elucidated on the basis of NMR and CD data. Haworforbin C (3) exhibited moderate inhibition of nitric oxide production in lipopolysaccharide-stimulated RAW264.7 cell line.
authors.affiliation: Faculty of Pharmaceutical Sciences, Hoshi University, Shinagawa-ku, Tokyo, Japan.
authors.forename: Fumie
authors.initials: F
authors.lastname: Yamasaki
authors.forename: Shoko
authors.initials: S
authors.lastname: Machida
authors.forename: Asami
authors.initials: A
authors.lastname: Nakata
authors.forename: Alfarius Eko
authors.initials: AE
authors.lastname: Nugroho
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Hirasawa
authors.forename: Toshio
authors.initials: T
authors.lastname: Kaneda
authors.forename: Osamu
authors.initials: O
authors.lastname: Shirota
authors.forename: Naoyuki
authors.initials: N
authors.lastname: Hagane
authors.forename: Tadayoshi
authors.initials: T
authors.lastname: Sugizaki
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Morita
mesh_terms: D000818:Animals; D002460:Cell Line; D005960:Glucosides / Q000737:chemistry* / Q000494:pharmacology*; D008070:Lipopolysaccharides / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D019684:Magnoliopsida / Q000737:chemistry*; D051379:Mice; D009569:Nitric Oxide / Q000378:metabolism; D052247:Nitric Oxide Synthase Type II / Q000378:metabolism; D010636:Phenols / Q000737:chemistry* / Q000494:pharmacology*
chemical_list: D005960:Glucosides; D008070:Lipopolysaccharides; D010636:Phenols; D009569:Nitric Oxide; D052247:Nitric Oxide Synthase Type II