title: [Treatment of clozapine-induced tachycardia with propranolol complicated by psoriasis].
abstract: A 25-year-old male developed sinus tachycardia after given clozapine for treatment-resistant psychosis in schizophrenia. The tachycardia was treated successfully with propranolol for several weeks. The patient developed skin eruptions, later diagnosed as psoriasis. Propranolol is known to be capable of causing, evoking or aggravating psoriasis. Several other drugs commonly used in psychiatric practice are also known to cause psoriasis. Doctors need to be aware to the possible side effects of such drugs because they can jeopardise the patient's wellbeing and reduce the efficacy of psychiatric treatment.
authors.affiliation: Delta psychiatrisch centrum, Postbus 800, 3170 DZ Poortugaal. d.van.dam@deltapsy.nl
authors.forename: D
authors.initials: D
authors.lastname: van Dam
authors.forename: T M
authors.initials: TM
authors.lastname: Bosch
authors.forename: E J
authors.initials: EJ
authors.lastname: Mookhoek
authors.forename: J E
authors.initials: JE
authors.lastname: Hovens
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000009:adverse effects / Q000627:therapeutic use; D000328:Adult; D014150:Antipsychotic Agents / Q000009:adverse effects / Q000627:therapeutic use; D003024:Clozapine / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D008297:Male; D011433:Propranolol / Q000009:adverse effects* / Q000627:therapeutic use*; D011565:Psoriasis / Q000139:chemically induced*; D011618:Psychotic Disorders / Q000188:drug therapy / Q000209:etiology; D012559:Schizophrenia / Q000150:complications / Q000188:drug therapy; D013610:Tachycardia / Q000139:chemically induced* / Q000188:drug therapy*
chemical_list: D000319:Adrenergic beta-Antagonists; D014150:Antipsychotic Agents; D011433:Propranolol; D003024:Clozapine