title: Pulmonary metastatic chordoma improved by platinum-based chemotherapy.
abstract: Chordomas are rare, low-grade, primary malignant bone tumors that are locally invasive and frequently recur. Despite the provision of radical excision as a primary treatment, local recurrences ultimately develop in most patients with chordoma. For these reasons, postoperative therapy such as radiation therapy is often required. However, the chemotherapy, as the treatment of chordoma relapse, has not only limited experiences but also considerable controversy on its effectiveness. In addition, in the case of pulmonary nodules, it is difficult to diagnose or suspect pulmonary metastatic chordoma initially due to its rarity and similar histologic features to other malignancies. Herein, we present an interesting case of metastatic chordoma in a 52-year old woman, which has been well controlled by platinum-based chemotherapy.
authors.affiliation: Department of Internal Medicine, Research Center for Pulmonary Disorders, Chonbuk National University Medical School, Jeonju, South Korea.
authors.forename: Min Hee
authors.initials: MH
authors.lastname: Lee
authors.forename: So Ri
authors.initials: SR
authors.lastname: Kim
authors.forename: Jae Seok
authors.initials: JS
authors.lastname: Jeong
authors.forename: Eun Jung
authors.initials: EJ
authors.lastname: Lee
authors.forename: Yong Chul
authors.initials: YC
authors.lastname: Lee
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001859:Bone Neoplasms / Q000188:drug therapy* / Q000473:pathology*; D002817:Chordoma / Q000188:drug therapy* / Q000473:pathology / Q000556:secondary*; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy* / Q000532:radiotherapy / Q000556:secondary*; D008875:Middle Aged; D009944:Organoplatinum Compounds / Q000008:administration & dosage
chemical_list: D009944:Organoplatinum Compounds