title: Treatment of multidrug-resistant tuberculosis in a high-prevalence region through a binational consortium.
abstract: We describe the outcome of treatment of multidrug-resistant tuberculosis (MDR-TB) in Baja California, Mexico, by a United States-Mexico consortium. From June 2006 to December 2010, 42 patients started treatment. Strains were resistant to 4.15 ± 1.3 drugs; all patients achieved  culture conversion on treatment after an average of 3.4 ± 1.6 months. A total of 19 patients (47.5%) were discharged as cured, 3 died (7.5%) and 1 defaulted (2.5%). MDR-TB cases can be cured under a well-organized out-patient program; in this consortium, the US partner introduced program  elements that were gradually integrated into the Mexican state TB program.
authors.affiliation: Instituto de Servicios de Salud Publica del Estado de Baja California, Baja California, Mexico. rlaniado@uabc.edu.mx
authors.forename: R
authors.initials: R
authors.lastname: Laniado-Laborín
authors.forename: J
authors.initials: J
authors.lastname: Estrada-Guzman
authors.forename: H
authors.initials: H
authors.lastname: Perez
authors.forename: F
authors.initials: F
authors.lastname: Batiz-Armenta
authors.forename: J M
authors.initials: JM
authors.lastname: Alcantar-Schramm
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000995:Antitubercular Agents / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007391:International Cooperation; D008297:Male; D008800:Mexico / Q000453:epidemiology; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D009313:National Health Programs / Q000458:organization & administration*; D015995:Prevalence; D016730:Program Development; D016896:Treatment Outcome; D018088:Tuberculosis, Multidrug-Resistant / Q000188:drug therapy* / Q000453:epidemiology / Q000382:microbiology; D014481:United States; D055815:Young Adult
chemical_list: D000995:Antitubercular Agents