title: [Gastric secretory function in psoriatic patients with chronic opistorchosis before and after antihelminthic therapy].
abstract: The aim of the work was to study secretory function of the stomach in psoriatic patients with chronic opistorchosis (CO) before and after antihelminthic therapy. It included 90 such patients, 70 with psoriasis alone, 70 with CO, and 30 healthy subjects. All patients were examined by oesophagogastroduodenoscopy. Fractional gastric secretion was measured. The secretory function of the stomach was most seriously disturbed in psoriatic patients with CO. It did not further deteriorate after antihelminthic therapy. The disturbance was associated with reduced hydrochloric acid and pepsin levels which confirms the necessity of antihelminthic therapy.
mesh_terms: D000871:Anthelmintics / Q000627:therapeutic use*; D002908:Chronic Disease; D015897:Comorbidity; D004334:Drug Administration Schedule; D016099:Endoscopy, Gastrointestinal; D005750:Gastric Juice / Q000378:metabolism*; D006801:Humans; D009889:Opisthorchiasis / Q000188:drug therapy* / Q000469:parasitology / Q000503:physiopathology*; D011565:Psoriasis / Q000150:complications / Q000469:parasitology / Q000503:physiopathology*; D016896:Treatment Outcome
chemical_list: D000871:Anthelmintics