title: Consensus standards for acquisition, measurement, and reporting of intravascular optical coherence tomography studies: a report from the International Working Group for Intravascular Optical Coherence Tomography Standardization and Validation.
abstract: OBJECTIVE
  The purpose of this document is to make the output of the International Working Group for Intravascular Optical Coherence Tomography (IWG-IVOCT) Standardization and Validation available to medical and scientific communities, through a peer-reviewed publication, in the interest of improving the diagnosis and treatment of patients with atherosclerosis, including coronary artery disease.
  
  
  BACKGROUND
  Intravascular optical coherence tomography (IVOCT) is a catheter-based modality that acquires images at a resolution of ~10 μm, enabling visualization of blood vessel wall microstructure in vivo at an unprecedented level of detail. IVOCT devices are now commercially available worldwide, there is an active user base, and the interest in using this technology is growing. Incorporation of IVOCT in research and daily clinical practice can be facilitated by the development of uniform terminology and consensus-based standards on use of the technology, interpretation of the images, and reporting of IVOCT results.
  
  
  METHODS
  The IWG-IVOCT, comprising more than 260 academic and industry members from Asia, Europe, and the United States, formed in 2008 and convened on the topic of IVOCT standardization through a series of 9 national and international meetings.
  
  
  RESULTS
  Knowledge and recommendations from this group on key areas within the IVOCT field were assembled to generate this consensus document, authored by the Writing Committee, composed of academicians who have participated in meetings and/or writing of the text.
  
  
  CONCLUSIONS
  This document may be broadly used as a standard reference regarding the current state of the IVOCT imaging modality, intended for researchers and clinicians who use IVOCT and analyze IVOCT data.
authors.affiliation: The Massachusetts General Hospital and the Wellman Center for Photomedicine, Boston, Massachusetts 02114, USA. gtearney@partners.org
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mesh_terms: D003324:Coronary Artery Disease / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D003328:Coronary Thrombosis / Q000175:diagnosis; D003331:Coronary Vessels / Q000000981:diagnostic imaging / Q000473:pathology*; D019317:Evidence-Based Medicine; D006801:Humans; D007391:International Cooperation; D008499:Medical Records / Q000592:standards*; D058226:Plaque, Atherosclerotic / Q000175:diagnosis; D012015:Reference Standards; D015203:Reproducibility of Results; D041623:Tomography, Optical Coherence / Q000592:standards*; D017539:Tunica Intima / Q000473:pathology; D014463:Ultrasonography