title: Rhodium-catalyzed enantioselective hydrogenation of unsaturated phosphonates by ClickFerrophos ligands.
abstract: Newly developed ClickFerrophos II ligands were applied in the hydrogenation of α,β-unsaturated phosphonates. The use of a rhodium/ClickFerrophos II catalyst was examined in the hydrogenation of functionalized α,β-unsaturated phosphonates and was revealed to be effective for β-alkyl-β-aryl or β-dialkyl phosphonates, (Z)-β-enolester phosphonates, and α-phenylethenyl phosphonates, producing the corresponding chiral phosphonates in good yields with high enantioselectivities (up to 96% ee).
authors.affiliation: Department of Applied Chemistry, Institute of Science and Engineering, Chuo University, 1-13-27 Kasuga, Bunkyo-ku, Tokyo 112-8551, Japan.
authors.forename: Takashi
authors.initials: T
authors.lastname: Konno
authors.forename: Kenta
authors.initials: K
authors.lastname: Shimizu
authors.forename: Kenichi
authors.initials: K
authors.lastname: Ogata
authors.forename: Shin-ichi
authors.initials: S
authors.lastname: Fukuzawa
mesh_terms: D002384:Catalysis; D006865:Hydrogenation; D008024:Ligands; D015394:Molecular Structure; D063065:Organophosphonates / Q000737:chemistry*; D009943:Organophosphorus Compounds / Q000737:chemistry*; D012238:Rhodium / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D008024:Ligands; D063065:Organophosphonates; D009943:Organophosphorus Compounds; D012238:Rhodium