title: An unexpected cause of progressive renal failure in a 66-year-old male after liver transplantation: secondary hyperoxaluria.
abstract: BACKGROUND
  Hyperoxaluria is a rare metabolic disorder characterized by calcium oxalate deposition in different tissues. It is caused either by an inherited disease of oxalate metabolism [primary hyperoxalurias (PH)] or by an acquired disturbance (secondary hyperoxaluria).
  
  
  METHODS
  We report here an atypical presentation of enteric hyperoxaluria-induced renal failure that occurred after liver transplantation. Despite adapted treatment and intensive haemodialysis, the patient did not recover. This case allows the reviewing of the multiple pathophysiological mechanisms involved in this disease.
  
  
  CONCLUSIONS
  Oxalate nephropathy should be considered in the differential diagnosis of acute renal failure, especially when previous renal impairment and fat malabsorption are present. We suggest performing renal biopsy early to allow a prompt diagnosis and therapeutic intervention.
authors.affiliation: Service de Néphrologie-Dialyse-Transplantation, CHU d'Angers, 4 rue Larrey, 49933, Angers cedex 9, France.
authors.forename: François
authors.initials: F
authors.lastname: Beloncle
authors.forename: Johnny
authors.initials: J
authors.lastname: Sayegh
authors.forename: Agnès
authors.initials: A
authors.lastname: Duveau
authors.forename: Virginie
authors.initials: V
authors.lastname: Besson
authors.forename: Anne
authors.initials: A
authors.lastname: Croue
authors.forename: Jean-François
authors.initials: JF
authors.lastname: Subra
authors.forename: Jean-François
authors.initials: JF
authors.lastname: Augusto
mesh_terms: D058186:Acute Kidney Injury / Q000175:diagnosis / Q000209:etiology / Q000473:pathology* / Q000628:therapy; D000368:Aged; D001707:Biopsy, Needle; D002129:Calcium Oxalate / Q000378:metabolism* / Q000652:urine; D003937:Diagnosis, Differential; D018450:Disease Progression; D005500:Follow-Up Studies; D006084:Graft Rejection / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D006801:Humans; D006959:Hyperoxaluria / Q000175:diagnosis / Q000209:etiology / Q000473:pathology* / Q000628:therapy; D007150:Immunohistochemistry; D017093:Liver Failure / Q000473:pathology / Q000601:surgery; D016031:Liver Transplantation / Q000009:adverse effects* / Q000379:methods; D008297:Male; D008859:Microscopy, Polarization; D006435:Renal Dialysis / Q000379:methods; D018570:Risk Assessment
chemical_list: D002129:Calcium Oxalate