title: The biology and chemistry of high-valent iron-oxo and iron-nitrido complexes.
abstract: Selective functionalization of unactivated C-H bonds and ammonia production are extremely important industrial processes. A range of metalloenyzmes achieve these challenging tasks in biology by activating dioxygen and dinitrogen using cheap and abundant transition metals, such as iron, copper and manganese. High-valent iron-oxo and -nitrido complexes act as active intermediates in many of these processes. The generation of well-described model compounds can provide vital insights into the mechanism of such enzymatic reactions. Advances in the chemistry of model high-valent iron-oxo and -nitrido systems can be related to our understanding of the biological systems.
authors.affiliation: Department of Chemistry and Pharmacy, Inorganic Chemistry, Friedrich-Alexander-University Erlangen - Nuremberg, Egerlandstr. 1, Erlangen 91058, Germany.
authors.forename: Johannes
authors.initials: J
authors.lastname: Hohenberger
authors.forename: Kallol
authors.initials: K
authors.lastname: Ray
authors.forename: Karsten
authors.initials: K
authors.lastname: Meyer
mesh_terms: D002384:Catalysis; D005290:Ferric Compounds / Q000737:chemistry*; D006418:Heme / Q000737:chemistry / Q000378:metabolism; D007501:Iron / Q000737:chemistry; D058085:Iron Compounds / Q000737:chemistry*; D008956:Models, Chemical; D008958:Models, Molecular; D009584:Nitrogen / Q000737:chemistry; D010100:Oxygen / Q000737:chemistry*
chemical_list: D005290:Ferric Compounds; D058085:Iron Compounds; C540999:iron nitrido complex; D006418:Heme; D007501:Iron; D009584:Nitrogen; D010100:Oxygen