title: Discitis and sacroiliitis diagnosed 15 years after iatrogenic Mycobacterium xenopi inoculation.
abstract: A patient was diagnosed with discitis and sacroiliitis due to Mycobacterium xenopi. He had a history of percutaneous nucleotomy performed 15 years earlier (in 1992) at the Clinique du Sport, Paris, France, during an outbreak of nosocomial M. xenopi infection at that institution. In 1997, magnetic resonance imaging performed as part of the routine follow-up program for patients who had surgery at the Clinique du Sport during the outbreak was not interpreted as indicating discitis; this assessment was confirmed by our review of the images. Bone and joint infections due to atypical mycobacteria are rare and can develop very slowly. To our knowledge, this is the first reported case of M. xenopi discitis with secondary extension to the sacroiliac joint in an immunocompetent patient.
authors.affiliation: Service de rhumatologie, CHU de Reims, 45, rue Cognac-Jay, 51100 Reims, France.
authors.forename: Jean-Hugues
authors.initials: JH
authors.lastname: Salmon
authors.forename: Guillaume
authors.initials: G
authors.lastname: Direz
authors.forename: Jean-Marc
authors.initials: JM
authors.lastname: Ziza
authors.forename: Nicole
authors.initials: N
authors.lastname: Desplaces
authors.forename: Pascal
authors.initials: P
authors.lastname: Brochot
authors.forename: Jean-Paul
authors.initials: JP
authors.lastname: Eschard
mesh_terms: D000904:Antibiotics, Antitubercular / Q000627:therapeutic use; D000995:Antitubercular Agents / Q000627:therapeutic use; D017291:Clarithromycin / Q000627:therapeutic use; D003428:Cross Infection / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D015299:Discitis / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D004196:Disease Outbreaks; D017587:Diskectomy, Percutaneous / Q000009:adverse effects; D004359:Drug Therapy, Combination; D004977:Ethambutol / Q000627:therapeutic use; D006801:Humans; D007121:Immunocompetence; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009165:Mycobacterium Infections, Nontuberculous / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D019912:Mycobacterium xenopi; D012293:Rifampin / Q000627:therapeutic use; D058566:Sacroiliitis / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D013530:Surgical Wound Infection / Q000382:microbiology*; D016896:Treatment Outcome
chemical_list: D000904:Antibiotics, Antitubercular; D000995:Antitubercular Agents; D004977:Ethambutol; D017291:Clarithromycin; D012293:Rifampin