title: Periodontal vaccine.
abstract: Vaccine is the name applied generally to a substance of the nature of dead or attenuated living infectious material introduced into the body with the object of increasing its power to resist or get rid of a disease. Vaccines are generally prophylactic, i.e. they ameliorate the effects of future infection. One such vaccine considered here is the "Periodontal vaccine". Till date, no preventive modality exists for periodontal disease and treatment rendered is palliative. Thus, availability of periodontal vaccine would not only prevent and modulate periodontal disease, but also enhance the quality of life of people for whom periodontal treatment cannot be easily obtained. The aim of the research should be development of a multispecies vaccine targeting the four prime periodontal pathogens, viz. Porphyromonas gingivalis, T. forsythus, T. denticola and A. comitans. Success is still elusive in case of periodontal vaccine due to the complex etiopathogenesis of the disease.
authors.affiliation: Department of Periodontology and Oral Implantology, National Dental College and Hospital, Gulabgarh, Derabassi, Distt. SAS Nagar, Mohali, Punjab, India. ranmal3@hotmail.com
authors.forename: Ranjan
authors.initials: R
authors.lastname: Malhotra
authors.forename: Anoop
authors.initials: A
authors.lastname: Kapoor
authors.forename: Vishakha
authors.initials: V
authors.lastname: Grover
authors.forename: Aaswin Kaur
authors.initials: AK
authors.lastname: Tuli
mesh_terms: D016976:Aggregatibacter actinomycetemcomitans / Q000276:immunology; D001426:Bacterial Proteins / Q000276:immunology; D001428:Bacterial Vaccines; D001439:Bacteroides / Q000276:immunology; D006801:Humans; D007114:Immunization; D007116:Immunization, Passive; D010510:Periodontal Diseases / Q000517:prevention & control*; D016966:Porphyromonas gingivalis / Q000276:immunology; D048373:Treponema denticola / Q000276:immunology
chemical_list: D001426:Bacterial Proteins; D001428:Bacterial Vaccines