title: Chemical constituents of Euphorbia hyberna L. (Euphorbiaceae).
abstract: Chemical investigation of the aerial part and the roots of Euphorbia hyberna L. subs. hyberna. resulted in the isolation and identification of four triterpenoids (3β-O-octadecanoyllupeol (1), glut-5-en-3β-ol (2), 24-methylenecicloartan-3β-ol (3) and cicloart-23-ene-3β,25-diol (6)) along with the phenolic compounds ellagic acid (4) and 3,3'-di-O-methylellagic acid (7). Although these are all known compounds, this is the first report of their isolation from this plant. Their structures were elucidated on the basis of spectral methods, including 2D NMR experiences, and confirmed by comparing with the literature data.
authors.affiliation: Department of Chemistry, Chemistry Centre of Vila Real, University of Trás-os-Montes and Alto Douro, 5001-911 Vila Real, Portugal.
authors.forename: Ana Margarida V D
authors.initials: AM
authors.lastname: Ferreira
authors.forename: Maria João M
authors.initials: MJ
authors.lastname: Carvalho
authors.forename: Miguel M
authors.initials: MM
authors.lastname: Sequeira
authors.forename: Artur M S
authors.initials: AM
authors.lastname: Silva
authors.forename: Luís H M
authors.initials: LH
authors.lastname: Carvalho
mesh_terms: D004610:Ellagic Acid / Q000031:analogs & derivatives / Q000737:chemistry; D028481:Euphorbia / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D018517:Plant Roots / Q000737:chemistry
chemical_list: C534594:3'-O-methylellagic acid; D004610:Ellagic Acid; C050401:3,3'-di-O-methylellagic acid