title: [Chronic HBV infection in a two year-old girl in spite of correct HBV vaccination after birth].
abstract: Our case story is about a two year-old girl who, despite full vaccination with neonatal hepatitis B immunoglobulin and hepatitis B vaccination and revaccination with hepatitis B vaccine at one, two and 12 months of age, got chronic hepatitis B presumably due to intrauterine mother-to-child transmission. Her mother was known to be HBsAg and HBeAg positive with genotype C and a viral load of one billion IU/ml. It is important that children with HBV infection are detected and seen in a special department. Post-vaccination screening of children from HBsAg positive mothers should be considered.
authors.affiliation: Børneafdeling GGK, Rigshospitalet, Blegdamsvej 9, 2100 København Ø, Denmark. heidismedegaard@hotmail.com
authors.forename: Heidi
authors.initials: H
authors.lastname: Smedegaard
authors.forename: Katja
authors.initials: K
authors.lastname: Harder
mesh_terms: D002675:Child, Preschool; D005260:Female; D006510:Hepatitis B Antibodies / Q000008:administration & dosage; D006514:Hepatitis B Surface Antigens / Q000235:genetics / Q000276:immunology; D006513:Hepatitis B e Antigens / Q000235:genetics / Q000276:immunology; D019694:Hepatitis B, Chronic / Q000276:immunology / Q000635:transmission; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D018445:Infectious Disease Transmission, Vertical; D019562:Viral Load / Q000276:immunology
chemical_list: D006510:Hepatitis B Antibodies; D006514:Hepatitis B Surface Antigens; D006513:Hepatitis B e Antigens