title: LOV domain-containing F-box proteins: light-dependent protein degradation modules in Arabidopsis.
abstract: Plants constantly survey the surrounding environment using several sets of photoreceptors. They can sense changes in the quantity (=intensity) and quality (=wavelength) of light and use this information to adjust their physiological responses, growth, and developmental patterns. In addition to the classical photoreceptors, such as phytochromes, cryptochromes, and phototropins, ZEITLUPE (ZTL), FLAVIN-BINDING, KELCH REPEAT, F-BOX 1 (FKF1), and LOV KELCH PROTEIN 2 (LKP2) proteins have been recently identified as blue-light photoreceptors that are important for regulation of the circadian clock and photoperiodic flowering. The ZTL/FKF1/LKP2 protein family possesses a unique combination of domains: a blue-light-absorbing LOV (Light, Oxygen, or Voltage) domain along with domains involved in protein degradation. Here, we summarize recent advances in our understanding of the function of the Arabidopsis ZTL/FKF1/LKP2 proteins. We summarize the distinct photochemical properties of their LOV domains and discuss the molecular mechanisms by which the ZTL/FKF1/LKP2 proteins regulate the circadian clock and photoperiodic flowering by controlling blue-light-dependent protein degradation.
authors.affiliation: Department of Biology, University of Washington, Seattle, WA 98195-1800, USA.
authors.forename: Shogo
authors.initials: S
authors.lastname: Ito
authors.forename: Young Hun
authors.initials: YH
authors.lastname: Song
authors.forename: Takato
authors.initials: T
authors.lastname: Imaizumi
mesh_terms: D000595:Amino Acid Sequence; D017360:Arabidopsis / Q000378:metabolism* / Q000528:radiation effects*; D029681:Arabidopsis Proteins / Q000737:chemistry* / Q000378:metabolism*; D057906:Circadian Clocks / Q000528:radiation effects; D044783:F-Box Proteins / Q000737:chemistry* / Q000378:metabolism*; D008027:Light; D008969:Molecular Sequence Data; D059748:Proteolysis / Q000528:radiation effects*
chemical_list: D029681:Arabidopsis Proteins; D044783:F-Box Proteins