title: Carbocyclization cascades of allyl ketenimines via aza-Claisen rearrangements of N-phosphoryl-N-allyl-ynamides.
abstract: A series of carbocyclization cascades of allyl ketenimines initiated through a thermal aza-Claisen rearrangement of N-phosphoryl-N-allyl ynamides is described. Interceptions of the cationic intermediate via Meerwein-Wagner rearrangements and polyene-type cyclizations en route to fused bi- and tricyclic frameworks are featured.
authors.affiliation: Division of Pharmaceutical Sciences and Department of Chemistry, University of Wisconsin, Madison, Wisconsin 53705, USA. dekorver@wisc.edu
authors.forename: Kyle A
authors.initials: KA
authors.lastname: DeKorver
authors.forename: Xiao-Na
authors.initials: XN
authors.lastname: Wang
authors.forename: Mary C
authors.initials: MC
authors.lastname: Walton
authors.forename: Richard P
authors.initials: RP
authors.lastname: Hsung
mesh_terms: D000498:Allyl Compounds / Q000737:chemistry*; D000577:Amides / Q000737:chemistry*; D001372:Aza Compounds / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D007097:Imines / Q000737:chemistry*; D015394:Molecular Structure
chemical_list: D000498:Allyl Compounds; D000577:Amides; D001372:Aza Compounds; D007097:Imines