title: A way to DAI.
abstract: RIP3-regulated necrosis has recently emerged as an important antiviral host defense mechanism. A new study by Upton et al. (2012) identifies DAI, a cytoplasmic DNA sensor, as a partner of RIP3 that is essential for the induction of regulated necrosis in cytomegalovirus-infected cells.
authors.affiliation: Institute for Genetics, University of Cologne, Cologne, Germany.
authors.forename: Patrick-Simon
authors.initials: PS
authors.lastname: Welz
authors.forename: Manolis
authors.initials: M
authors.lastname: Pasparakis