title: Clinicopathological characteristics and treatment outcomes of adult patients with paratesticular rhabdomyosarcoma (PRMS): A 10-year single-centre experience.
abstract: BACKGROUND
  We report our experience with 8 consecutive adults treated for paratesticular rhabdomyosarcoma (RMS) at a single institution between 2000 and 2010.
  
  
  METHODS
  After primary surgical excision, 7 patients were classified into group I according to the Intergroup Rhabdomyosarcoma Study Group (IRSG) Postsurgical Grouping Classification, and 1 patient into group IIB. Retroperitoneal node dissection was not a required staging procedure. Adjuvant chemotherapy was administered to 7 of the 8 patients. No additional radiotherapy was administered.
  
  
  RESULTS
  The median age at diagnosis was 24 years (range: 18-60). Embryonal histology was the most common (75%) subtype. During follow-up, 3 patients experienced local relapse and 5 distant relapse. The median progression-free and overall survival times were 17.0 ± 9.9 months (range: 5-31) and 27.3 ± 1.3 months (range: 16-58), respectively.
  
  
  CONCLUSIONS
  Paratesticular RMS is an uncommon malignancy in adults. We confirm that patients with localized paratesticular RMS may have different prognoses. Retroperitoneal lymphadenectomy can be avoided as a treatment for paratesticular RMS after radical inguinal orchiectomy.
authors.affiliation: Department of Medical Oncology, Institute of Oncology, University of Istanbul, Istanbul, Turkey;
authors.forename: Serkan
authors.initials: S
authors.lastname: Keskin
authors.forename: Meltem
authors.initials: M
authors.lastname: Ekenel
authors.forename: Mert
authors.initials: M
authors.lastname: Basaran
authors.forename: Isin
authors.initials: I
authors.lastname: Kilicaslan
authors.forename: Murat
authors.initials: M
authors.lastname: Tunc
authors.forename: Sevil
authors.initials: S
authors.lastname: Bavbek