title: Podocytes: gaining a foothold.
abstract: In an attempt to understand the basis of glomerular disease, significant progress has been made in understanding the mechanisms that determine podocyte development and the maintenance of podocyte health. This review examines recent advances in this area focusing on the podocyte intercellular junction, actin cytoskeletal dynamics, and determinants of podocyte cell polarity, autophagy and mTOR biology.
authors.affiliation: Division of Nephrology, University of Michigan, Ann Arbor, MI, USA.
authors.forename: Puneet
authors.initials: P
authors.lastname: Garg
authors.forename: Lawrence B
authors.initials: LB
authors.lastname: Holzman
mesh_terms: D000818:Animals; D016764:Cell Polarity; D006801:Humans; D007365:Intercellular Junctions / Q000378:metabolism; D007674:Kidney Diseases / Q000378:metabolism; D007678:Kidney Glomerulus / Q000378:metabolism; D008565:Membrane Proteins / Q000378:metabolism; D050199:Podocytes / Q000378:metabolism*
chemical_list: D008565:Membrane Proteins