title: Mosquito infection studies with Aotus monkeys and humans infected with the Chesson strain of Plasmodiun vivax.
abstract: Oocyst counts were compared between mosquitoes that fed on humans versus mosquitoes that fed on Aotus monkeys, both of which were infected with the Chesson strain of Plasmodium vivax. Oocyst counts obtained from mosquitoes fed on humans were almost 10-fold higher in number. Mosquitoes were more likely to be infected and with a higher rate of infection when they fed on monkeys before the peak in the asexual parasite count. Mosquitoes that fed on humans were more likely to be more heavily infected when fed after the peak in the asexual count. Of several species of owl monkeys, Aotus vociferans was infected at a higher frequency. On the basis of oocyst counts, Anopheles dirus were the most susceptible and An. maculatus were the least susceptible of the mosquito species tested.
authors.affiliation: Division of Parasitic Diseases and Malaria, Centers for Disease Control and Prevention, Atlanta, Georgia, USA. wec1@cdc.gov
authors.forename: William E
authors.initials: WE
authors.lastname: Collins
authors.forename: JoAnn S
authors.initials: JS
authors.lastname: Sullivan
authors.forename: Geoffrey M
authors.initials: GM
authors.lastname: Jeffery
authors.forename: Douglas
authors.initials: D
authors.lastname: Nace
authors.forename: Tyrone
authors.initials: T
authors.lastname: Williams
authors.forename: G Gale
authors.initials: GG
authors.lastname: Galland
authors.forename: Allison
authors.initials: A
authors.lastname: Williams
authors.forename: John W
authors.initials: JW
authors.lastname: Barnwell
mesh_terms: D000818:Animals; D000852:Anopheles / Q000469:parasitology*; D000962:Antimalarials / Q000627:therapeutic use; D016645:Aotidae / Q000469:parasitology*; D002738:Chloroquine / Q000627:therapeutic use; D019468:Disease Management; D004195:Disease Models, Animal; D006790:Host-Parasite Interactions; D006801:Humans; D008288:Malaria / Q000469:parasitology / Q000662:veterinary; D008297:Male; D008992:Monkey Diseases / Q000469:parasitology; D010966:Plasmodium vivax / Q000472:pathogenicity*; D011319:Primaquine / Q000627:therapeutic use; D002727:Proguanil / Q000627:therapeutic use; D011739:Pyrimethamine / Q000627:therapeutic use; D011803:Quinine / Q000627:therapeutic use
chemical_list: D000962:Antimalarials; D002738:Chloroquine; D011803:Quinine; D011319:Primaquine; D002727:Proguanil; D011739:Pyrimethamine