title: [Dynamics of the protein content of human urine during 5-day immersion].
abstract: Variations in the protein spectrum (12 groups) of native daily urine were studied during 5-day dry immersion (DI) of 14 subjects at the age of 19 to 26 years using gradient electrophoresis in polyacrylamide gel. Protein excretion with urine did not alter in the course of the experiment. However, the urine proteins spectrum trended to some shifts. Excretion of low-molecular proteins decreased and of albumin increased pointing to remodulation of tubular reabsorption initiated by the experimental conditions. Steady growth of the Tamm-Horsfall protein concentration seems to be a defense reaction. There was an incremental decrease in immunoglobulins that could be associated with a reduction of glomerular filter permeability for high-molecular proteins.
authors.forename: A L
authors.initials: AL
authors.lastname: Vorontsov
authors.forename: A Iu
authors.initials: AIu
authors.lastname: Nesterovskaia
authors.forename: B L
authors.initials: BL
authors.lastname: Morukov
authors.forename: A A
authors.initials: AA
authors.lastname: Markin
authors.forename: O A
authors.initials: OA
authors.lastname: Zhuravleva
authors.forename: I V
authors.initials: IV
authors.lastname: Zabolotskaia
authors.forename: L V
authors.initials: LV
authors.lastname: Vostrikova
mesh_terms: D000328:Adult; D000337:Aerospace Medicine; D000419:Albuminuria / Q000652:urine; D004591:Electrophoresis, Polyacrylamide Gel / Q000379:methods; D006801:Humans; D007101:Immersion; D007136:Immunoglobulins / Q000652:urine*; D008297:Male; D009043:Motor Activity / Q000502:physiology; D011506:Proteins / Q000378:metabolism*; D014556:Urine / Q000737:chemistry*; D058949:Uromodulin / Q000652:urine*; D014893:Weightlessness
chemical_list: D007136:Immunoglobulins; D011506:Proteins; D058949:Uromodulin