title: Cutis laxa-like mycosis fungoides.
abstract: Mycosis fungoides is the most common form of primary cutaneous T-cell lymphoma. Several clinical and clinicopathological variants of mycosis fungoides have been reported. A 75-year-old woman presenting with multiple ill-defined areas of marked cutaneous wrinkling on the trunk and extremities is reported. Histopathological examination showed characteristic features of mycosis fungoides along with an interstitial dermal infiltrate composed predominantly of atypical lymphocytes with histiocytes intermingled within the collagen bundles. A focal reduction and fragmentation of elastic fibers was demonstrated. This observation illustrates a peculiar and previously unreported clinicopathological presentation of mycosis fungoides: cutis laxa-like mycosis fungoides, expanding the spectrum of mycosis fungoides variants associated with abnormalities of the dermal elastic fibers.
authors.affiliation: Department of Dermatology, Hospital del Mar, Barcelona, Spain. dlopezaventin@parcdesalutmar.cat
authors.forename: Daniel
authors.initials: D
authors.lastname: López Aventín
authors.forename: Fernando
authors.initials: F
authors.lastname: Gallardo
authors.forename: Inmaculada
authors.initials: I
authors.lastname: Gil
authors.forename: Gemma
authors.initials: G
authors.lastname: Martín-Ezquerra
authors.forename: Mar
authors.initials: M
authors.lastname: García
authors.forename: Beatriz
authors.initials: B
authors.lastname: Bellosillo
authors.forename: Núria
authors.initials: N
authors.lastname: Juanpere
authors.forename: Ramon M
authors.initials: RM
authors.lastname: Pujol
mesh_terms: D000368:Aged; D003483:Cutis Laxa / Q000175:diagnosis*; D003937:Diagnosis, Differential; D004547:Elastic Tissue / Q000473:pathology; D005260:Female; D006801:Humans; D009182:Mycosis Fungoides / Q000175:diagnosis* / Q000473:pathology; D012878:Skin Neoplasms / Q000175:diagnosis* / Q000473:pathology