title: Sensorimotor cortical activation in patients with sleep bruxism.
abstract: Sleep bruxism is assumed to be triggered by a dysfunctional subcortical and cortical network. This study investigates sensorimotor cortical activation in patients with sleep bruxism during clenching and chewing. Nine polysomnographically diagnosed patients and nine healthy control subjects underwent magnetoencephalography (MEG). During clenching and chewing, patients with bruxism revealed significantly larger event-related desynchronization in the somatomotor area (Brodmann area 4) than healthy subjects. Group differences in the muscle activity were ruled out by electromyography (EMG) assessments during MEG. This result might be regarded as a consequence of increased sensorimotor cortical representation of the tongue and chewing musculature due to an enhanced parafunctional muscle activity in bruxers potentially triggered by occlusal factors. Alternatively, a secondary activation of cortical structures during sleep bruxism in the context of an activated network of subcortical and cortical structures might lead to increased cortical representation of the chewing musculature via use dependent plasticity.
authors.affiliation: Department of Prosthodontics and Material Sciences, University of Münster, Münster, Germany.
authors.forename: Bedia B
authors.initials: BB
authors.lastname: Kervancioglu
authors.forename: Inga K
authors.initials: IK
authors.lastname: Teismann
authors.forename: Melanie
authors.initials: M
authors.lastname: Rain
authors.forename: Sybille
authors.initials: S
authors.lastname: Hugger
authors.forename: Joanne A
authors.initials: JA
authors.lastname: Boeckmann
authors.forename: Peter
authors.initials: P
authors.lastname: Young
authors.forename: Wolfram
authors.initials: W
authors.lastname: Schwindt
authors.forename: Christo
authors.initials: C
authors.lastname: Pantev
authors.forename: Stephan
authors.initials: S
authors.lastname: Doering
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D002540:Cerebral Cortex / Q000503:physiopathology*; D004576:Electromyography; D005260:Female; D006801:Humans; D007568:Jaw / Q000502:physiology; D015225:Magnetoencephalography; D008297:Male; D008406:Masseter Muscle / Q000502:physiology; D008409:Mastication / Q000502:physiology; D017286:Polysomnography; D020186:Sleep Bruxism / Q000503:physiopathology*; D055815:Young Adult