title: Successful treatment of imported mucosal Leishmania infantum leishmaniasis with miltefosine after severe hypokalemia under meglumine antimoniate treatment.
abstract: Old World mucosal leishmaniasis is a rare but regularly reported disease in Southern Europe. We report the case of a 64-year-old woman who developed severe hypokalemia under meglumine antimoniate treatment and was successfully treated under second line therapy with miltefosine.
authors.affiliation: Swiss Tropical and Public Health Institute, Basel, Switzerland. andreas.neumayr@unibas.ch
authors.forename: Andreas L C
authors.initials: AL
authors.lastname: Neumayr
authors.forename: Clemens
authors.initials: C
authors.lastname: Walter
authors.forename: Marcel
authors.initials: M
authors.lastname: Stoeckle
authors.forename: Natalie
authors.initials: N
authors.lastname: Braendle
authors.forename: Kathrin
authors.initials: K
authors.lastname: Glatz
authors.forename: Johannes A
authors.initials: JA
authors.lastname: Blum
mesh_terms: D000818:Animals; D018926:Anti-Allergic Agents / Q000627:therapeutic use; D000981:Antiprotozoal Agents / Q000008:administration & dosage / Q000009:adverse effects; D001145:Arrhythmias, Cardiac / Q000175:diagnosis / Q000209:etiology; D001706:Biopsy; D004333:Drug Administration Routes; D057915:Drug Substitution; D004562:Electrocardiography; D019353:Endemic Diseases; D005076:Exanthema / Q000139:chemically induced / Q000628:therapy; D005260:Female; D006115:Greece; D006801:Humans; D007008:Hypokalemia / Q000097:blood / Q000139:chemically induced / Q000150:complications / Q000628:therapy; D007303:Insect Vectors; D007558:Italy; D018314:Leishmania infantum / Q000187:drug effects / Q000302:isolation & purification; D007898:Leishmaniasis, Visceral / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology / Q000635:transmission; D008536:Meglumine / Q000008:administration & dosage / Q000009:adverse effects; D000077485:Meglumine Antimoniate; D008875:Middle Aged; D009018:Morocco; D009061:Mouth Mucosa / Q000473:pathology; D019226:Oral Ulcer / Q000188:drug therapy / Q000209:etiology / Q000473:pathology / Q000503:physiopathology; D009942:Organometallic Compounds / Q000008:administration & dosage / Q000009:adverse effects; D010767:Phosphorylcholine / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives*; D011188:Potassium / Q000097:blood / Q000627:therapeutic use; D011576:Psychodidae; D013030:Spain; D014195:Travel; D016896:Treatment Outcome
chemical_list: D018926:Anti-Allergic Agents; D000981:Antiprotozoal Agents; D009942:Organometallic Compounds; D010767:Phosphorylcholine; C039128:miltefosine; D008536:Meglumine; D000077485:Meglumine Antimoniate; D011188:Potassium