title: Biochemistry to the rescue: a ClC-2 auxiliary subunit provides a tangible link to leukodystrophy.
abstract: ClC-2 is a broadly distributed chloride channel with an enigmatic neurophysiological function. In this issue of Neuron, Jeworutzki et al. (2012) use a biochemical approach to identify GlialCAM, a protein with a defined link to leukodystrophy, as a ClC-2 auxiliary subunit.
authors.affiliation: Department of Molecular and Cellular Physiology, Stanford University, 279 Campus Drive West, Stanford, CA 94305, USA. maduke@stanford.edu
authors.forename: Merritt C
authors.initials: MC
authors.lastname: Maduke
authors.forename: Richard J
authors.initials: RJ
authors.lastname: Reimer