title: [Laparoscopic fundoplication results in the treatment of the non-gastrointestinal symptoms of gastroesophageal reflux].
abstract: BACKGROUND
  Gastroesophageal reflux disease (GERD) can trigger typical and atypical symptoms (cough, dysphonia, asthma…). GERD with typical symptoms has well established surgical indications, but it is not the case when the symptoms are atypical. Our aim is to assess the effectiveness of laparoscopic surgery in those patients in whom the surgical indication was mainly due to atypical symptoms.
  
  
  METHODS
  Between 1998 and 2011 laparoscopic fundoplication was performed on of 318 patients with GERD, of whom 14 (4%) had atypical symptoms as the main indication. Typical symptoms were present in 12 (86%) cases, and atypical symptoms were: cough in 5 (36%) cases, respiratory symptoms 5 (36%), dysphonia 2 (14%), vocal chords granuloma 1 (7%) and larynx spasm 1 (7%). The GERD diagnosis was established due to evidence of an anatomical or functional alterations of the gastroesophageal junction (hiatus hernia, pathological manometry or pH-metry). The clinical histories of the patients were reviewed and they were given a gastrointestinal quality of life (Gastrointestinal Quality of Life Index [GIQoL]) questionnaire was completed, as well as a subjective assessment (0 to 4) of the modification of their atypical symptoms.
  
  
  RESULTS
  A clinical improvement was observed in both the atypical and typical GERD in 12 patients (86%), with the symptoms score decreasing from 3.7 to 0.7. A significant improvement (P<.05) from the pre-surgical value 107(±26) to 122 (±10) points was obtained in the quality of life (GIQoL) in 11 patients (79%).
  
  
  CONCLUSIONS
  Laparoscopic fundoplication is an effective technique in the treatment of the atypical symptoms of GERD.
authors.affiliation: Hospital de la Santa Creu i Sant Pau, Barcelona, España.
authors.forename: Aurora
authors.initials: A
authors.lastname: Carrasquer
authors.forename: Eduardo M
authors.initials: EM
authors.lastname: Targarona
authors.forename: Franco
authors.initials: F
authors.lastname: Marinello
authors.forename: Xavier
authors.initials: X
authors.lastname: Batlle
authors.forename: Manuel
authors.initials: M
authors.lastname: Trias
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D018662:Fundoplication / Q000379:methods*; D005764:Gastroesophageal Reflux / Q000150:complications*; D006801:Humans; D010535:Laparoscopy; D008297:Male; D008875:Middle Aged; D011788:Quality of Life; D012189:Retrospective Studies; D013997:Time Factors; D055815:Young Adult