title: Clarithromycin monohydrate: a synchrotron X-ray powder study.
abstract: In the crystal structure of the title compound, clarithromycin (CAM) monohydrate, C(38)H(69)NO(13)·H(2)O, the water mol-ecule behaves as a proton donor and is hydrogen bonded to the hy-droxy O atom of the CAM cladinose ring. The hy-droxy O atom also behaves as a proton donor, forming an inter-molecular hydrogen bond with one of the hy-droxy groups of the 14-membered aglycone ring. The CAM mol-ecules are linked through these hydrogen bonds into chains running parallel to the c axis.
authors.forename: Shuji
authors.initials: S
authors.lastname: Noguchi
authors.forename: Sadahiro
authors.initials: S
authors.lastname: Fujiki
authors.forename: Yasunori
authors.initials: Y
authors.lastname: Iwao
authors.forename: Keiko
authors.initials: K
authors.lastname: Miura
authors.forename: Shigeru
authors.initials: S
authors.lastname: Itai