title: Active learning strategies for the deduplication of electronic patient data using classification trees.
abstract: BACKGROUND
  Supervised record linkage methods often require a clerical review to gain informative training data. Active learning means to actively prompt the user to label data with special characteristics in order to minimise the review costs. We conducted an empirical evaluation to investigate whether a simple active learning strategy using binary comparison patterns is sufficient or if string metrics together with a more sophisticated algorithm are necessary to achieve high accuracies with a small training set.
  
  
  METHODS
  Based on medical registry data with different numbers of attributes, we used active learning to acquire training sets for classification trees, which were then used to classify the remaining data. Active learning for binary patterns means that every distinct comparison pattern represents a stratum from which one item is sampled. Active learning for patterns consisting of the Levenshtein string metric values uses an iterative process where the most informative and representative examples are added to the training set. In this context, we extended the active learning strategy by Sarawagi and Bhamidipaty (2002).
  
  
  RESULTS
  On the original data set, active learning based on binary comparison patterns leads to the best results. When dropping four or six attributes, using string metrics leads to better results. In both cases, not more than 200 manually reviewed training examples are necessary.
  
  
  CONCLUSIONS
  In record linkage applications where only forename, name and birthday are available as attributes, we suggest the sophisticated active learning strategy based on string metrics in order to achieve highly accurate results. We recommend the simple strategy if more attributes are available, as in our study. In both cases, active learning significantly reduces the amount of manual involvement in training data selection compared to usual record linkage settings.
authors.affiliation: Institute of Medical Biostatistics, Epidemiology and Informatics, University Medical Centre of the Johannes Gutenberg University Mainz, Germany. murat.sariyar@unimedizin-mainz.de
authors.forename: M
authors.initials: M
authors.lastname: Sariyar
authors.forename: A
authors.initials: A
authors.lastname: Borg
authors.forename: K
authors.initials: K
authors.lastname: Pommerening
mesh_terms: D000465:Algorithms; D001185:Artificial Intelligence; D003663:Decision Trees; D057286:Electronic Health Records; D006801:Humans; D016247:Information Storage and Retrieval; D008498:Medical Record Linkage / Q000379:methods*