title: A caged cyanide.
abstract: A photoactivatable caged cyanide, 1-(2-nitrophenyl)ethyl (NPE) cyanide, was synthesized, which upon irradiation in the near UV releases cyanide. It is demonstrated that the compound can be used to induce formation of the Fe(III)-CN(-) complex in the heme protein nitrophorin 4 from Rhodnius prolixus.
authors.affiliation: Max-Planck-Institut für Bioanorganische Chemie, Stifstrasse 34-36, D-45470 Mülheim an der Ruhr, Germany. mknipp@mpi-muelheim.mpg.de
authors.forename: Markus
authors.initials: M
authors.lastname: Knipp
authors.forename: Johanna J
authors.initials: JJ
authors.lastname: Taing
authors.forename: Chunmao
authors.initials: C
authors.lastname: He
authors.forename: Cristiano
authors.initials: C
authors.lastname: Viappiani
mesh_terms: D000818:Animals; D056831:Coordination Complexes / Q000138:chemical synthesis / Q000737:chemistry; D003486:Cyanides / Q000737:chemistry*; D005290:Ferric Compounds / Q000737:chemistry; D006420:Hemeproteins / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism; D011994:Recombinant Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D012239:Rhodnius / Q000378:metabolism; D012471:Salivary Proteins and Peptides / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism; D014466:Ultraviolet Rays
chemical_list: D056831:Coordination Complexes; D003486:Cyanides; D005290:Ferric Compounds; D006420:Hemeproteins; D011994:Recombinant Proteins; D012471:Salivary Proteins and Peptides; C090560:nitrophorin