title: [Suppression of spiral waves and spatiotemporal chaos in cardiac tissue by elevating potassium ion concentration].
abstract: The suppression of spiral waves and spatiotemporal chaos in cardiac tissue was studied based on cardiac model. We proposed two strategies of suppressing spiral wave and spatiotemporal chaos. One was to elevate the extracellular potassium ion concentration suddenly. This method can effectively suppress spiral waves and spatiotemporal chaos when the elevated extracellular potassium ion concentration reaches a critical value, especially when the spiral wave pinned to defects also can be suppressed. The other was to let the extracellular potassium ion concentration varies periodically while the amplitude of concentration was limited. We found that the method could effectively suppress spiral waves and spatiotemporal chaos when the related parameters were properly chosen. But it can not suppress the pinned spiral waves. And the control mechanism is discussed in this paper.
authors.affiliation: (College of Physical and Technology, Guangxi Normal University, Guilin 541004, China.
authors.forename: Xianghua
authors.initials: X
authors.lastname: Xiao
authors.forename: Guoning
authors.initials: G
authors.lastname: Tang
mesh_terms: D000200:Action Potentials / Q000502:physiology; D001145:Arrhythmias, Cardiac / Q000150:complications / Q000503:physiopathology*; D003198:Computer Simulation; D006321:Heart / Q000502:physiology*; D006801:Humans; D008955:Models, Cardiovascular; D011188:Potassium / Q000378:metabolism*
chemical_list: D011188:Potassium