title: Two- and three-dimensional models for the visualization of jaw tumors based on CT-MRI image fusion.
abstract: OBJECTIVE
  The objective of this study was to demonstrate the feasibility of two- and three-dimensional (2D and 3D) models based on computed tomography-magnetic resonance imaging (CT-MRI) image fusion for the visualization of jaw tumors.
  
  
  METHODS
  Seven patients with proved jaw tumors were involved in this study. Both preoperative CT and MRI image data were acquired in DICOM format and imported into Surgicase CMF software, respectively. Then, the structures of interest, including tumor, muscle, and vascular, and so on, were segmented based on different thresholds and reconstructed in 3D texture. Finally, CT-MRI image fusion was semiautomatically performed to obtain the fused 2D images and 3D models for the visualization of jaw tumors. The qualities of the fused 2D images and 3D models together with their potential applications in surgical management of jaw tumors were qualitatively assessed. Besides, the importance of this imaging technique in terms of training junior surgeons was also discussed in detail.
  
  
  RESULTS
  Computed tomography-MRI image fusion clearly showed the relationship between tumors and adjacent structures. The qualitative assessment of fused images was satisfied.
  
  
  CONCLUSIONS
  Although there are some limitations, the 2D images and 3D models based on CT-MRI image fusion can provide a powerful tool for the visualization of jaw tumors. It may offer surgeons an assisted tool for the subject-specific preoperative planning, surgical simulation, and intraoperative guidance for jaw tumors. Furthermore, it also may offer valuable 2D and 3D models for training junior surgeons or provide a useful tool for surgeons to communicate well with patients.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Ninth People's Hospital, Shanghai Key Laboratory of Stomatology, Shanghai, China.
authors.forename: Jiewen
authors.initials: J
authors.lastname: Dai
authors.forename: Xudong
authors.initials: X
authors.lastname: Wang
authors.forename: Yuefu
authors.initials: Y
authors.lastname: Dong
authors.forename: Hongbo
authors.initials: H
authors.lastname: Yu
authors.forename: Danling
authors.initials: D
authors.lastname: Yang
authors.forename: Guofang
authors.initials: G
authors.lastname: Shen
mesh_terms: D000328:Adult; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D021621:Imaging, Three-Dimensional / Q000379:methods*; D007573:Jaw Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D012984:Software; D014057:Tomography, X-Ray Computed / Q000379:methods*; D016896:Treatment Outcome