title: [Molecular epidemiology of multidrug-resistant organisms].
abstract: Recent advance in molecular epidemiology of multidrug-resistant organisms (MDROs) was described. Most of MDROs are spreading over the world in a short period, monitoring of certain epidemic strains of MDROs is very important. Since Cantor et al. developed pulsed-field gel electrophoresis (PFGE) in 1984, genotyping tools became major tools for laboratory based-epidemiologic analysis. Recent advance was developed by two major technologies. One is multilocus sequence typing (MLST) and the other one is matrix assisted laser desorption ionization-time of flight-mass spectrometry (MALDI-TOF-MS). MALDI-TOF-MS technology is still under developing, but near future it will become major tools for MDROs molecular epidemiology.
authors.affiliation: Department of Infection Prevention and Control, Yokohama City University Hospital.
authors.forename: Toshihiro
authors.initials: T
authors.lastname: Mitsuda
mesh_terms: D001424:Bacterial Infections / Q000453:epidemiology*; D024901:Drug Resistance, Multiple, Bacterial / Q000235:genetics*; D006801:Humans; D017720:Molecular Epidemiology