title: [Severe community-acquired and hospital-acquired pneumonia].
abstract: Severe community-acquired pneumonia and hospital-acquired pneumonia are common infectious diseases in Germany. They are associated with high mortality especially in the old and multimorbid patient and are thus a challenge in daily clinical practice. While the CRB65 is a thoroughly validated score for risk stratification in community-acquired pneumonia, there is no comparable score for hospital-acquired pneumonia yet. Early initiation of adequate antibiotic treatment is essential for a positive outcome. Hospital-acquired pneumonia is more often associated with multidrug-resistant bacteria, which should be considered in the choice of initial treatment especially if the patient can be considered a member of a risk group. This article focuses on severe pneumonia and gives an overview of the recent guidelines and discusses newly published results.
authors.affiliation: Medizinische Klinik III, Universitätsklinikum Schleswig-Holstein, Campus Lübeck, Ratzeburger Allee 160, 23538, Lübeck, Deutschland.
authors.forename: L
authors.initials: L
authors.lastname: Witte
authors.forename: D
authors.initials: D
authors.lastname: Drömann
mesh_terms: D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D017714:Community-Acquired Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000401:mortality; D003428:Cross Infection / Q000175:diagnosis* / Q000188:drug therapy / Q000401:mortality; D024901:Drug Resistance, Multiple, Bacterial; D006801:Humans; D008826:Microbial Sensitivity Tests; D018410:Pneumonia, Bacterial / Q000175:diagnosis* / Q000188:drug therapy / Q000401:mortality; D053717:Pneumonia, Ventilator-Associated / Q000175:diagnosis / Q000188:drug therapy / Q000401:mortality; D011024:Pneumonia, Viral / Q000175:diagnosis* / Q000188:drug therapy / Q000401:mortality; D011552:Pseudomonas Infections / Q000175:diagnosis / Q000188:drug therapy / Q000401:mortality; D011550:Pseudomonas aeruginosa; D012307:Risk Factors
chemical_list: D000900:Anti-Bacterial Agents