title: Closure of the patent ductus arteriosus with the new duct occluder II additional sizes device.
abstract: OBJECTIVE
  The objective of this study was to evaluate the technical feasibility, safety, and efficacy of the new device Amplatzer duct occluder II additional sizes (ADO II AS) for closure of patent ductus arteriosus (PDA).
  
  
  BACKGROUND
  Transcatheter device closure is the standard care for PDA. Currently available technology is not designed for closure of small PDA in young children.
  
  
  METHODS
  From April to July 2011, seven children (five females, median age 1.5 years, median weight 11.4 kg) underwent PDA closure with the ADO II AS. Six had isolated PDA, one had PDA associated with preductal coarctation. We evaluated early and short-term results.
  
  
  RESULTS
  All but one PDA was closed via an antegrade approach. Mean fluoroscopy and procedural times were 8.0 ± 3.9 and 49.8 ± 27.9 min, respectively. No complications occurred. Immediate trivial residual shunt was present in one patient. In all devices, the retention disks laid flat against the walls of the pulmonary artery and aorta, without protrusion into the vessel lumen. The echocardiography performed after 24 hr did not show any residual shunt. At a median follow-up of 2 months, the PDAs were completely occluded without obstruction of the pulmonary arteries or aorta.
  
  
  CONCLUSIONS
  The new device ADO II AS was safely deployed with complete resolution of the PDA shunt. The lower profile and symmetry of this device allows for venous or arterial approach and smaller delivery catheter size. The ADO II AS might be a preferable alternative for closure of small-moderate PDAs.
authors.affiliation: Department of Cardiology, Paediatric Hospital Regina Margherita, Turin, Italy. gabriella.agnoletti@oirmsantanna.piemonte.it
authors.forename: Gabriella
authors.initials: G
authors.lastname: Agnoletti
authors.forename: D
authors.initials: D
authors.lastname: Marini
authors.forename: A M
authors.initials: AM
authors.lastname: Villar
authors.forename: R
authors.initials: R
authors.lastname: Bordese
authors.forename: F
authors.initials: F
authors.lastname: Gabbarini
mesh_terms: D001027:Aortography; D006328:Cardiac Catheterization / Q000009:adverse effects / Q000295:instrumentation*; D002648:Child; D002675:Child, Preschool; D004374:Ductus Arteriosus, Patent / Q000175:diagnosis / Q000628:therapy*; D018618:Echocardiography, Doppler, Color; D005240:Feasibility Studies; D005260:Female; D005471:Fluoroscopy; D006801:Humans; D007223:Infant; D007558:Italy; D008297:Male; D011474:Prosthesis Design; D015641:Radiography, Interventional; D013997:Time Factors; D016896:Treatment Outcome