title: Two new oleanane-type saponins from the husks of Xanthoceras sorbifolia Bunge.
abstract: Two new oleanane-type pentacyclic triterpenoid saponins were isolated from the husks of Xanthoceras sorbifolia Bunge and their structures were elucidated as 3-O-β-D-glucopyranosyl (1 → 6)-β-D-glucopyranosyl-28-O-α-L-rhamnopyranosyl (1 → 2) [β-D-glucopyranosyl (1 → 6)] β-D-glucopyranosyl-21β,22α-dihydroxyl-olean-12,15-diene and 3-O-β-D-glucopyranosyl (1 → 2)-β-D-glucopyranosyl-28-O-α-L-rhamnopyranosyl (1 → 2) [β-D-glucopyranosyl (1 → 6)] β-D-glucopyranosy-21β,22α-dihydroxyl-olean-12-ene. Meanwhile, the cytotoxic activities of these two compounds were tested on human gastric cancer cell (SGC-7901) and hepatoma carcinoma cell (HepG-2).
authors.affiliation: College of Pharmacy, Liaoning University of Traditional Chinese Medicine, 77 Life one Road, Dalian 116600, China.
authors.forename: Ying-Ying
authors.initials: YY
authors.lastname: Li
authors.forename: Zheng
authors.initials: Z
authors.lastname: Xiang
authors.forename: Hao
authors.initials: H
authors.lastname: Cui
authors.forename: Hang
authors.initials: H
authors.lastname: Xiao
authors.forename: Ting-Guo
authors.initials: TG
authors.lastname: Kang
authors.forename: De-Qiang
authors.initials: DQ
authors.lastname: Dou
authors.forename: Hai-Xue
authors.initials: HX
authors.lastname: Kuang
mesh_terms: D045744:Cell Line, Tumor; D049109:Cell Proliferation / Q000187:drug effects; D056945:Hep G2 Cells; D006801:Humans; D009828:Oleanolic Acid / Q000031:analogs & derivatives* / Q000737:chemistry / Q000494:pharmacology; D012503:Saponins / Q000737:chemistry* / Q000494:pharmacology*
chemical_list: D012503:Saponins; C413246:oleanane; D009828:Oleanolic Acid