title: Formal alkylation of allenes through highly selective radical cyclizations of allene-enes.
abstract: Something radical: the first example of alkene-to-allene radical cyclization of allene-enes is reported. The highly chemoselective intermolecular radical addition reaction of the alkene and subsequent, exclusive exo-radical addition to the allene was realized with perfluoroalkyl radicals. A subsequent TBAF-promoted dehydroiodination of the cyclization products forms cyclopentanes and regenerates an allene moiety (TBAF=tetra-n-butylammonium fluoride).
authors.affiliation: Laboratory of Molecular Recognition and Synthesis, Department of Chemistry, Zhejiang University, Hangzhou, PR China.
authors.forename: Rong
authors.initials: R
authors.lastname: Zeng
authors.forename: Chunling
authors.initials: C
authors.lastname: Fu
authors.forename: Shengming
authors.initials: S
authors.lastname: Ma