title: Unambiguous structure of atractyloside and carboxyatractyloside.
abstract: Atractyloside (ATR) was characterized in 1868 and until now structural studies on diterpenic moiety had been done through the characterization of ATR derivatives; while the glycosidic moiety seemed to be a β-D-glucopyranose a recent crystal structure of the mitochondrial ATP/ADP carrier in complex with CATR showed an α-D-glucopyranose. We decided to re-examine the ATR and CATR structures by crystallographic study of ATR.
authors.affiliation: Université de Bordeaux, IBGC, UMR5095, Laboratoire de Physiologie Moléculaire et Cellulaire, Bordeaux, France.
authors.forename: Jean-Frédéric
authors.initials: JF
authors.lastname: Sanchez
authors.forename: Brice
authors.initials: B
authors.lastname: Kauffmann
authors.forename: Axelle
authors.initials: A
authors.lastname: Grélard
authors.forename: Corinne
authors.initials: C
authors.lastname: Sanchez
authors.forename: Véronique
authors.initials: V
authors.lastname: Trézéguet
authors.forename: Ivan
authors.initials: I
authors.lastname: Huc
authors.forename: Guy J-M
authors.initials: GJ
authors.lastname: Lauquin
mesh_terms: D001278:Atractyloside / Q000031:analogs & derivatives* / Q000737:chemistry*; D018360:Crystallography, X-Ray; D008958:Models, Molecular; D046912:Multiprotein Complexes / Q000737:chemistry
chemical_list: D046912:Multiprotein Complexes; D001278:Atractyloside; C003853:carboxyatractyloside