title: [Melatonin agonist: a possible disease-modifying agent for Alzheimer's disease].
abstract: Recent advance of therapeutic intervention makes immunotherapies disease-modifying therapy for Alzheimer's disease. Several lines of evidence indicated that melatonin or indole structures are candidates for disease-modifying agents in Alzheimer's disease. We herein reviewed the in vivo efficacy of melatonin in a transgenic model of Alzheimer's disease and discuss about a potential of melatonin agonist for treating Alzheimer's disease.
authors.affiliation: Department of Neurology, Institute of Brain Science, Hirosaki University Graduate School of Medicine.
authors.forename: Etsuro
authors.initials: E
authors.lastname: Matsubara
mesh_terms: D000544:Alzheimer Disease / Q000188:drug therapy*; D000818:Animals; D006801:Humans; D008550:Melatonin / Q000819:agonists* / Q000627:therapeutic use; D051379:Mice
chemical_list: D008550:Melatonin