title: Donor quality of life after living donor liver transplantation: single-institute experience.
abstract: OBJECTIVE
  Living donor liver transplantation (LDLT) has been widely accepted because of the severe shortage of hepatic grafts. However, the healthy donor is exposed to risks of morbidity and mortality. In this study, we analyzed medical, functional, and psychological outcomes of donors after hepatectomy for liver donation.
  
  
  METHODS
  Among 41 donor hepatectomy cases for LDLT performed in our institute from January 1994 to May 2011, we reviewed the medical records (liver function tests, complications, etc) of 27 subjects who donated to recipients older than 12 years. We also performed a questionnaire survey based on the Japanese Short Form-36 version 2 Health Survey scales as a measure of physical and mental health, to which 31 subjects responded.
  
  
  RESULTS
  Six of the 27 donors experienced prolonged jaundice. Their ratios of graft volume/standard donor liver volume (GV/SDLV) were higher than those of the 21 donors without prolonged jaundice (60.0% vs 41.5%). According to the questionnaires, social functioning among those having undergone emergency hepatectomy as well as general health perceptions declined in those with postoperative complications. Physical component summary declined among those having undergone emergency hepatectomy and with postoperative complications.
  
  
  CONCLUSIONS
  In liver donation from a living donor, massive hepatectomy should be avoided. A ratio of GV/SDLV around 50% seems reasonable. Donors with emergency transplantations or postoperative complications must be more carefully followed after donor hepatectomy.
authors.affiliation: Department of Gastroenterological Surgery, Hirosaki University Graduate School of Medicine, Hirosaki, Aomori, Japan. ytoyoki@cc.hirosaki-u.ac.jp
authors.forename: Y
authors.initials: Y
authors.lastname: Toyoki
authors.forename: K
authors.initials: K
authors.lastname: Ishido
authors.forename: D
authors.initials: D
authors.lastname: Kudo
authors.forename: M
authors.initials: M
authors.lastname: Umehara
authors.forename: N
authors.initials: N
authors.lastname: Kimura
authors.forename: S
authors.initials: S
authors.lastname: Narumi
authors.forename: M
authors.initials: M
authors.lastname: Sugai
authors.forename: K
authors.initials: K
authors.lastname: Hakamada
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006498:Hepatectomy / Q000009:adverse effects / Q000523:psychology*; D006801:Humans; D007564:Japan; D007565:Jaundice / Q000209:etiology / Q000523:psychology; D016031:Liver Transplantation / Q000009:adverse effects / Q000523:psychology*; D019520:Living Donors / Q000523:psychology*; D008297:Male; D008875:Middle Aged; D011788:Quality of Life; D011795:Surveys and Questionnaires; D013997:Time Factors; D016896:Treatment Outcome