title: Hyperprolactinemia in a patient with a pituitary adenoma receiving antipsychotic drug therapy.
abstract: Hyperprolactinemia is a common consequence of treatment with an antipsychotic medication. It can result in hypogonadism due to the inhibitory effect of elevated prolactin levels on the hypothalamic-pituitary-gonadal hormonal axis. We present a case of hypogonadism secondary to hyperprolactinemia in a patient taking antipsychotic medication, with radiological evidence of a pituitary microadenoma. The relevance and investigation of hyperprolactinemia in patients being treated with antipsychotic medications are discussed.
authors.affiliation: Wellington Regional Hospital, Capital and Coast DHB, New Zealand.
authors.forename: Richard W
authors.initials: RW
authors.lastname: Carroll
authors.forename: Polyxeni
authors.initials: P
authors.lastname: Christodoulou
authors.forename: Kevin C R
authors.initials: KC
authors.lastname: Baynes
authors.forename: David A
authors.initials: DA
authors.lastname: Kahn
mesh_terms: D000328:Adult; D014150:Antipsychotic Agents / Q000009:adverse effects*; D005260:Female; D005687:Galactorrhea / Q000139:chemically induced*; D006801:Humans; D006966:Hyperprolactinemia / Q000139:chemically induced* / Q000150:complications; D007006:Hypogonadism / Q000209:etiology*; D018810:Magnetic Resonance Angiography; D010911:Pituitary Neoplasms / Q000175:diagnosis*
chemical_list: D014150:Antipsychotic Agents