title: Ocular involvement in hospitalized patients with candidemia: analysis at a Boston tertiary care center.
abstract: OBJECTIVE
  To study the prevalence, microbial profile, and risk factors for ocular involvement in patients with candidemia.
  
  
  METHODS
  The records of all inpatient consultations requested at the Brigham and Women's Hospital from October 2009 to June 2011 to evaluate for ocular involvement in patients with candidemia were retrospectively reviewed.
  
  
  RESULTS
  Forty-nine consults were requested to rule out ocular involvement in patients with candidemia. The mean patient age was 55 years. In decreasing frequency, the organisms isolated were Candida albicans (42%), Candida parapsilosis (23%), Candida glabrata (17%), Candida tropicalis (8%), Candida dublinensis (5%), Candida krusei (3%), and Candida lusitaniae (3%). All patients were on antifungal treatment at the time of their initial ophthalmologic examination. One patient had evidence of chorioretinitis, and 3 patients had nonspecific fundus findings. Common risk factors included presence of an intravenous catheter, malignancy, and abdominal surgery.
  
  
  CONCLUSIONS
  Ocular involvement is rare among patients with systemic Candida infection.
authors.affiliation: Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts, USA.
authors.forename: Nancy
authors.initials: N
authors.lastname: Huynh
authors.forename: Han-Ying Peggy
authors.initials: HY
authors.lastname: Chang
authors.forename: Sheila
authors.initials: S
authors.lastname: Borboli-Gerogiannis
mesh_terms: D000005:Abdomen / Q000601:surgery; D000293:Adolescent; D000328:Adult; D000935:Antifungal Agents / Q000627:therapeutic use; D001900:Boston / Q000453:epidemiology; D002175:Candida / Q000302:isolation & purification; D058387:Candidemia / Q000188:drug therapy / Q000453:epidemiology*; D055499:Catheter-Related Infections / Q000453:epidemiology / Q000382:microbiology; D005128:Eye Diseases / Q000453:epidemiology* / Q000382:microbiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000150:complications; D011183:Postoperative Complications / Q000453:epidemiology / Q000382:microbiology; D015995:Prevalence; D012307:Risk Factors; D016896:Treatment Outcome
chemical_list: D000935:Antifungal Agents