title: Chemical constituents of the aerial part of Derris elliptica.
abstract: A new coumaronochromone, 6,4'-dihydroxy-7,5' -dimethoxy-coumaronochromone (1), together with eleven known flavonoids (2-12) were isolated from the ethanol extract of the aerial part of Derris elliptica. Their structures were elucidated on the basis of spectroscopic analysis. Compounds 2, 4, 7, 8 and 9 exhibited moderate insecticidal activities against larvae of Aedes albopictus. All compounds showed strong cytotoxic activities against Spodoptera litura (SL) and Trichoplusia ni BTI-Tn-5B1-4 (Hi-5) cells comparison to positive control of rotenone.
authors.affiliation: Key Laboratory of Natural Pesticide and Chemical Biology, Ministry of Education, South China Agricultural University, Guangzhou 510642, People's Republic of China.
authors.forename: Xinzhou
authors.initials: X
authors.lastname: Wu
authors.forename: Zhijun
authors.initials: Z
authors.lastname: Song
authors.forename: Hanhong
authors.initials: H
authors.lastname: Xu
authors.forename: Heng
authors.initials: H
authors.lastname: Zhang
authors.forename: Weiquan
authors.initials: W
authors.lastname: Chen
authors.forename: Huaying
authors.initials: H
authors.lastname: Liu
mesh_terms: D000330:Aedes / Q000187:drug effects*; D000818:Animals; D001572:Benzofurans / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D002460:Cell Line; D002867:Chromones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D029866:Derris / Q000737:chemistry*; D005419:Flavonoids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D007306:Insecticides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D007814:Larva / Q000187:drug effects; D015394:Molecular Structure; D009036:Moths / Q000187:drug effects*; D035261:Plant Components, Aerial / Q000737:chemistry*; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology; D012402:Rotenone / Q000494:pharmacology
chemical_list: C575122:6,4'-dihydroxy-7,5'-dimethoxy-coumaronochromone; D001572:Benzofurans; D002867:Chromones; D005419:Flavonoids; D007306:Insecticides; D010936:Plant Extracts; D012402:Rotenone