title: [Support of hematological homeostasis during chemotherapy with taxanes].
abstract: Study group consisted of 84 oncological patients with various tumor localization that received chemotherapy with taxanes. Medium follow up was 32.1 +/- 2.1 months. All patients had morphologic verification of the process. Distribution according to tumor localization was as follows: breast cancer--60 (71.4%), ovarian cancer--13 (15.5%), lung cancer--7 (8.3%), other localizations--4 (4.8%). Age varied from 22 to 73 years old. All patients had normal hematological status and survival expectation more than 3 months. Hematological complications were mentioned after the first cycle of chemotherapy in 70% cases.
authors.forename: I A
authors.initials: IA
authors.lastname: Koroleva
authors.forename: A S
authors.initials: AS
authors.lastname: Mochalova
mesh_terms: D000328:Adult; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000009:adverse effects*; D001943:Breast Neoplasms / Q000188:drug therapy; D002208:Caproates; D000077143:Docetaxel; D005260:Female; D005334:Fever / Q000209:etiology / Q000517:prevention & control; D005500:Follow-Up Studies; D006706:Homeostasis / Q000187:drug effects; D006801:Humans; D007093:Imidazoles / Q000008:administration & dosage / Q000627:therapeutic use*; D008175:Lung Neoplasms / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000188:drug therapy* / Q000473:pathology; D009503:Neutropenia / Q000139:chemically induced* / Q000150:complications / Q000175:diagnosis / Q000517:prevention & control*; D010051:Ovarian Neoplasms / Q000188:drug therapy; D017239:Paclitaxel / Q000009:adverse effects; D011471:Prostatic Neoplasms / Q000188:drug therapy; D020011:Protective Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D012720:Severity of Illness Index; D013274:Stomach Neoplasms / Q000188:drug therapy; D043823:Taxoids / Q000008:administration & dosage / Q000009:adverse effects*; D014062:Tongue Neoplasms / Q000188:drug therapy
chemical_list: D002208:Caproates; D007093:Imidazoles; D020011:Protective Agents; D043823:Taxoids; D000077143:Docetaxel; C539419:pentanedioic acid imidazolyl ethanamide; D017239:Paclitaxel