title: [Resistance training reduces the metabolic acidosis and hepatic and renal hypertrophy caused by the consumption of a high protein diet in rats].
abstract: BACKGROUND
  High protein (HP) diet consumption may adversely affect metabolic acidosis and hepatic and renal health. Despite such potentially adverse effect, there are only few studies analyzing the effects of resistance training on the parameters that could be altered by such diets.
  
  
  METHODS
  A total of 32 adult male Wistar rats were randomly distributed in 4 experimental groups (n = 8): normoprotein or HP diets, with or without resistance training. Diets were based on a whey protein hydrolyzate, and the experimental period lasted for 90 days.
  
  
  CONCLUSIONS
  Consumption of HP diets and resistance training significantly affected food intake, body composition and plasmatic levels of total cholesterol and triglycerides. Consumption of HP diets led to a considerable increase in liver and kidney weight (P < 0.001), urinary volume and acidity, as well as in the urinary excretion of Ca, with a parallel reduction in the urinary excretion of citrate (P < 0.05). The buffering action of resistance training on such diet-induced alterations was especially evident in the levels of hepatic and plasma triglycerides, plasmatic urea, and in liver and kidney weight (P < 0.001).
  
  
  CONCLUSIONS
  Resistance training had a protective action against alterations of hepatic and renal health status and some metabolic parameters like hepatic and plasma triglycerides.
authors.affiliation: Departamento de Fisiología e Instituto de Nutrición y Tecnología de los Alimentos, Facultad de Farmacia, Universidad de Granada, Granada, España.
authors.forename: V A
authors.initials: VA
authors.lastname: Aparicio
authors.forename: E
authors.initials: E
authors.lastname: Nebot
authors.forename: G
authors.initials: G
authors.lastname: Kapravelou
authors.forename: C
authors.initials: C
authors.lastname: Sánchez
authors.forename: J M
authors.initials: JM
authors.lastname: Porres
authors.forename: M
authors.initials: M
authors.lastname: López Jurado
authors.forename: P
authors.initials: P
authors.lastname: Aranda
mesh_terms: D000138:Acidosis / Q000209:etiology* / Q000517:prevention & control*; D000818:Animals; D002118:Calcium / Q000652:urine; D002784:Cholesterol / Q000097:blood; D002951:Citrates / Q000652:urine; D004044:Dietary Proteins / Q000009:adverse effects*; D004435:Eating; D006984:Hypertrophy; D007674:Kidney Diseases / Q000453:epidemiology* / Q000517:prevention & control*; D008107:Liver Diseases / Q000209:etiology* / Q000517:prevention & control*; D008297:Male; D008894:Milk Proteins; D009929:Organ Size; D010805:Physical Conditioning, Animal / Q000502:physiology*; D051381:Rats; D017208:Rats, Wistar; D014280:Triglycerides / Q000097:blood; D014508:Urea / Q000097:blood; D000067816:Whey Proteins
chemical_list: D002951:Citrates; D004044:Dietary Proteins; D008894:Milk Proteins; D014280:Triglycerides; D000067816:Whey Proteins; D014508:Urea; D002784:Cholesterol; D002118:Calcium