title: A novel mechanism of bacterial adaptation mediated by copper-dependent RNA polymerase σ factors.
abstract: One of the mechanisms widely used by bacteria to adapt to their environment is mediated by alternative σ factors. Here we discuss the mechanism of action of a novel metal-dependent ECF σ factor, whose ability to bind DNA depends on the redox state of copper.
authors.affiliation: Departamento de Microbiología, Facultad de Ciencias, Universidad de Granada, Granada, Spain. jdorado@ugr.es
authors.forename: José
authors.initials: J
authors.lastname: Muñoz-Dorado
authors.forename: Nuria
authors.initials: N
authors.lastname: Gómez-Santos
authors.forename: Juana
authors.initials: J
authors.lastname: Pérez
mesh_terms: D000222:Adaptation, Physiological; D001419:Bacteria / Q000201:enzymology / Q000378:metabolism*; D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism*; D003300:Copper / Q000378:metabolism*; D016941:Myxococcus xanthus / Q000378:metabolism; D012808:Sigma Factor / Q000235:genetics / Q000378:metabolism*; D015398:Signal Transduction; D013312:Stress, Physiological; D014158:Transcription, Genetic
chemical_list: D001426:Bacterial Proteins; D012808:Sigma Factor; D003300:Copper