title: Medical consequences and associations with untreated sleep-related breathing disorders and outcomes of treatments.
abstract: Sleep-related breathing disorders are a broad group of disorders that include obstructive sleep apnea, central sleep apnea, and periodic breathing disorders. This article reviews the scientific literature that links SRBD to various medical conditions including hypertension, coronary artery disease, cardiac arrhythmias, stroke, diabetes mellitus, obesity, and depression. Pathophysiologic mechanisms by which SRBD may contribute to these disorders will be discussed, as will data on the degree to which treatment of SRBD may improve these conditions.
authors.affiliation: St. John's Medical Plaza Sleep Disorders Center, Santa Monica, Calif, USA.
authors.forename: Daniel
authors.initials: D
authors.lastname: Norman
authors.forename: Paul B
authors.initials: PB
authors.lastname: Haberman
authors.forename: Edwin M
authors.initials: EM
authors.lastname: Valladares
mesh_terms: D001145:Arrhythmias, Cardiac / Q000209:etiology; D003324:Coronary Artery Disease / Q000209:etiology; D003863:Depression / Q000209:etiology; D003920:Diabetes Mellitus / Q000209:etiology; D006801:Humans; D006973:Hypertension / Q000209:etiology; D009765:Obesity / Q000209:etiology; D012891:Sleep Apnea Syndromes / Q000150:complications* / Q000628:therapy; D020182:Sleep Apnea, Central / Q000150:complications / Q000628:therapy; D020181:Sleep Apnea, Obstructive / Q000150:complications / Q000628:therapy; D020521:Stroke / Q000209:etiology; D016896:Treatment Outcome