title: Selective oxidation of unactivated C-H bonds by supramolecular control.
abstract: Efficient methods for dioxirane-based selective C-H bond oxidation by supramolecular control in H(2)O have been developed. With β-cyclodextrin as the supramolecular host, site-selective oxidation of the terminal over the internal tertiary C-H bond of 3,7-dimethyloctyl esters 3a-c was achieved. In addition, β-cyclodextrin selectively enhanced the C-H bond oxidation of cumene in a mixture of cumene and ethyl benzene in H(2)O. Through (1)H NMR studies, the selectivity in C-H bond oxidation could be attributed to the inclusion complex formation between β-cyclodextrin and the substrates.
authors.affiliation: State Key Laboratory of Chirosciences and Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Hong Kong, China.
authors.forename: Yat-Sing
authors.initials: YS
authors.lastname: Fung
authors.forename: Siu-Cheong
authors.initials: SC
authors.lastname: Yan
authors.forename: Man-Kin
authors.initials: MK
authors.lastname: Wong