title: Neurodegeneration: Trouble in the cell's powerhouse.
authors.forename: Derek P
authors.initials: DP
authors.lastname: Narendra
authors.forename: Richard J
authors.initials: RJ
authors.lastname: Youle
mesh_terms: D000818:Animals; D006360:Heat-Shock Proteins / Q000172:deficiency / Q000235:genetics / Q000378:metabolism; D006801:Humans; D051379:Mice; D008928:Mitochondria / Q000378:metabolism / Q000473:pathology*; D028361:Mitochondrial Diseases / Q000235:genetics / Q000378:metabolism / Q000473:pathology; D024101:Mitochondrial Proteins / Q000172:deficiency / Q000235:genetics / Q000378:metabolism; D009128:Muscle Spasticity / Q000235:genetics / Q000378:metabolism / Q000473:pathology*; D053140:Organelle Shape; D011689:Purkinje Cells / Q000378:metabolism / Q000473:pathology; D011792:Quebec; D020754:Spinocerebellar Ataxias / Q000151:congenital* / Q000235:genetics / Q000378:metabolism / Q000473:pathology
chemical_list: D006360:Heat-Shock Proteins; D024101:Mitochondrial Proteins; C404403:SACS protein, human; C498616:Sacs protein, mouse