title: Semantic similarity-based alignment between clinical archetypes and SNOMED CT: an application to observations.
abstract: OBJECTIVE
  One of the main challenges of eHealth is semantic interoperability of health systems. But, this will only be possible if the capture, representation and access of patient data is standardized. Clinical data models, such as OpenEHR Archetypes, define data structures that are agreed by experts to ensure the accuracy of health information. In addition, they provide an option to normalize clinical data by means of binding terms used in the model definition to standard medical vocabularies. Nevertheless, the effort needed to establish the association between archetype terms and standard terminology concepts is considerable. Therefore, the purpose of this study is to provide an automated approach to bind OpenEHR archetypes terms to the external terminology SNOMED CT, with the capability to do it at a semantic level.
  
  
  METHODS
  This research uses lexical techniques and external terminological tools in combination with context-based techniques, which use information about structural and semantic proximity to identify similarities between terms and so, to find alignments between them. The proposed approach exploits both the structural context of archetypes and the terminology context, in which concepts are logically defined through the relationships (hierarchical and definitional) to other concepts.
  
  
  RESULTS
  A set of 25 OBSERVATION archetypes with 477 bound terms was used to test the method. Of these, 342 terms (74.6%) were linked with 96.1% precision, 71.7% recall and 1.23 SNOMED CT concepts on average for each mapping. It has been detected that about one third of the archetype clinical information is grouped logically. Context-based techniques take advantage of this to increase the recall and to validate a 30.4% of the bindings produced by lexical techniques.
  
  
  CONCLUSIONS
  This research shows that it is possible to automatically map archetype terms to a standard terminology with a high precision and recall, with the help of appropriate contextual and semantic information of both models. Moreover, the semantic-based methods provide a means of validating and disambiguating the resulting bindings. Therefore, this work is a step forward to reduce the human participation in the mapping process.
authors.affiliation: Department of Electronics and Computer Science, Campus Vida, University of Santiago de Compostela, Spain. maria.meizoso@usc.es
authors.forename: María
authors.initials: M
authors.lastname: Meizoso García
authors.forename: José Luis
authors.initials: JL
authors.lastname: Iglesias Allones
authors.forename: Diego
authors.initials: D
authors.lastname: Martínez Hernández
authors.forename: María Jesús
authors.initials: MJ
authors.lastname: Taboada Iglesias
mesh_terms: D006801:Humans; D008498:Medical Record Linkage / Q000592:standards*; D016347:Medical Records Systems, Computerized; D008962:Models, Theoretical; D012660:Semantics; D039061:Systematized Nomenclature of Medicine