title: [Guideline for antiretroviral therapy of HIV-infected children and adolescents].
abstract: The HIV-infection in adults or children and adolescent differs substantially. Differences include the mode of infection, viral dynamics facing a developing immune system and the clinical course of the infection. In addition to the virological, immunological and epidemiological aspects the psychosocial situation is also very different. The above aspects and the decreased number of antiretroviral substances underline the need for specific guidelines for HIV-therapy in children and adolescents. The German Pediatric Working group AIDS (PAAD) has formulated this guideline in 2011 based on new study results, changes in international recommendations and newly available drugs.
authors.affiliation: Universitätsklinikum Düsseldorf, Klinik für Kinder-Onkologie, -Hämatologie und Klinische Immunologie, Düsseldorf.
authors.forename: J
authors.initials: J
authors.lastname: Neubert
authors.forename: T
authors.initials: T
authors.lastname: Niehues
authors.forename: U
authors.initials: U
authors.lastname: Baumann
authors.forename: B
authors.initials: B
authors.lastname: Buchholz
authors.forename: G
authors.initials: G
authors.lastname: Notheis
authors.forename: U
authors.initials: U
authors.lastname: Wintergerst
authors.forename: J
authors.initials: J
authors.lastname: Blume
authors.forename: C
authors.initials: C
authors.lastname: Feiterna-Sperling
authors.forename: H-J
authors.initials: HJ
authors.lastname: Laws
authors.forename: R
authors.initials: R
authors.lastname: Linde
authors.forename: C
authors.initials: C
authors.lastname: Königs
mesh_terms: D000293:Adolescent; D019380:Anti-HIV Agents / Q000009:adverse effects / Q000627:therapeutic use*; D018791:CD4 Lymphocyte Count; D002648:Child; D002675:Child, Preschool; D004311:Double-Blind Method; D024882:Drug Resistance, Viral; D004359:Drug Therapy, Combination; D019317:Evidence-Based Medicine; D015658:HIV Infections / Q000175:diagnosis / Q000188:drug therapy* / Q000821:virology; D006801:Humans; D007223:Infant; D011379:Prognosis; D016032:Randomized Controlled Trials as Topic; D019562:Viral Load; D055815:Young Adult
chemical_list: D019380:Anti-HIV Agents