title: New synthesis approach for hybrid Gd(III)-loaded Nanocrystalline TiO2 as potential magnetic resonance imaging contrast agents.
abstract: A new aqueous "in situ and one pot" method to elaborate surface-functionalized Gd(III)-doped anatase TiO2 nanoparticles, starting from heterometallic/heteroleptic Gd-Ti alkoxides, is reported. Full characterization and thermal behaviour of the nanomaterials demonstrate that this molecular approach offers the convenience of working under soft temperature and pH conditions in order to allow fine tuning of the organic surface functionalization and gadolinium doping. In vitro phantom images exhibit potential MRI T1-contrast agent properties.
authors.affiliation: University Lyon 1, Institut de Recherches sur la Catalyse et I'Environnement de LYON (IRCELYON), UMR-CNRS 5256, 2 avenue Albert Einstein, 69626 Villeurbanne cedex, France.
authors.forename: Violaine
authors.initials: V
authors.lastname: Mendez
authors.forename: Stéphane
authors.initials: S
authors.lastname: Daniele