title: Escherichia coli pyomyositis in an immunocompromised host.
abstract: BACKGROUND
  Pyomyositis due to Escherichia coli (E. coil) is rarely reported in immunocompromised patients with hematological malignancy.
  
  
  METHODS
  We present a case report of a 34-year-old man who developed E. coli pyomyositis as a complication of acute myelogenous leukemia (AML). Magnetic resonance imaging (MRI) of the right hip suggested myofascial infection of the gluteal muscles, and a needle muscle aspiration grew E. coli phylogenetic group B2. The patient responded to intravenous piperacillin/tazobactam followed by prolonged oral levofloxacin.
  
  
  CONCLUSIONS
  Pyomyositis should be suspected in all immunocompromised patients complaining of muscle pain and may exhibit signs of localized muscle infection. Appropriate antibiotic therapy targeting fluoroquinolone-resistant E. coli should be considered for initial empiric therapy of pyomyositis in immunocompromised patients.
authors.affiliation: Hospital Medicine, Mayo Clinic Health System, 700 West Ave S, La Crosse, WI 54601, USA. sharma.umesh@mayo.edu
authors.forename: Umesh
authors.initials: U
authors.lastname: Sharma
authors.forename: William R
authors.initials: WR
authors.lastname: Schwan
authors.forename: William A
authors.initials: WA
authors.lastname: Agger
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002081:Buttocks; D003937:Diagnosis, Differential; D004927:Escherichia coli Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D006801:Humans; D016867:Immunocompromised Host; D015470:Leukemia, Myeloid, Acute / Q000150:complications*; D008279:Magnetic Resonance Imaging; D008297:Male; D052880:Pyomyositis / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology
chemical_list: D000900:Anti-Bacterial Agents