title: The antibacterial and antiplaque effectiveness of mouthwashes containing cetylpyridinium chloride with and without alcohol in improving gingival health.
abstract: This article briefly discusses the antibacterial action ofcetylpyridinium chloride (CPC) and its efficacy in the removal of bacterial plaque as an adjunct to the mechanical cleaning of tooth surfaces. It reviews new studies on the effectiveness of mouthwash formulations containing CPC against two common oral bacteria species and in disrupting plaque biofilms. Finally, this article reviews three clinical studies which support that the daily use of mouthwashes containing 0.075% CPC, with and without alcohol, represents a valuable complement to daily mechanical plaque control.
authors.affiliation: Colgate-Palmolive Technology Center, Piscataway, NJ, USA. malcolm_williams@colpal.com
authors.forename: Malcolm I
authors.initials: MI
authors.lastname: Williams
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D000891:Anti-Infective Agents, Local / Q000737:chemistry / Q000627:therapeutic use*; D018441:Biofilms / Q000187:drug effects; D002594:Cetylpyridinium / Q000737:chemistry / Q000627:therapeutic use*; D002626:Chemistry, Pharmaceutical; D003773:Dental Plaque / Q000382:microbiology / Q000517:prevention & control*; D000431:Ethanol; D005882:Gingival Diseases / Q000517:prevention & control*; D006801:Humans; D009067:Mouthwashes / Q000737:chemistry / Q000627:therapeutic use*; D014677:Pharmaceutical Vehicles
chemical_list: D000900:Anti-Bacterial Agents; D000891:Anti-Infective Agents, Local; D009067:Mouthwashes; D014677:Pharmaceutical Vehicles; D000431:Ethanol; D002594:Cetylpyridinium