title: F-18 FDG PET/CT imaging of solitary liver Langerhans cell histiocytosis: preliminary findings.
abstract: Langerhans cell histiocytosis (LCH) is a disorder of clonal proliferation of Langerhans-type cells. The imaging findings of LCH are not specific. A 27-year-old woman was admitted to our hospital because of liver enzyme elevation without other hepatic signs. Radiological studies were originally interpreted as possible metastatic disease to the liver. Fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography (F-18 FDG PET/CT) images demonstrated a diffuse pattern of nodules in the liver with hypermetabolic activity. LCH was diagnosed histopathologically with an ultrasound-guided liver biopsy. This case illustrates the importance of considering proliferative/benign conditions of the liver when interpreting PET/CT. Failure to do so could result in patient mismanagement.
authors.affiliation: Department of Hematology, Changhai Hospital, 168 Changhai Road, Shanghai, 200433, China.
authors.forename: Xiaoxia
authors.initials: X
authors.lastname: Hu
authors.forename: Aisheng
authors.initials: A
authors.lastname: Dong
authors.forename: Shuqing
authors.initials: S
authors.lastname: Lv
authors.forename: Qian
authors.initials: Q
authors.lastname: Wang
authors.forename: Xianbao
authors.initials: X
authors.lastname: Zhan
authors.forename: Xianmin
authors.initials: X
authors.lastname: Song
authors.forename: Jianmin
authors.initials: J
authors.lastname: Wang
mesh_terms: D000328:Adult; D005260:Female; D019788:Fluorodeoxyglucose F18; D006646:Histiocytosis, Langerhans-Cell / Q000000981:diagnostic imaging*; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D008099:Liver / Q000000981:diagnostic imaging*; D064847:Multimodal Imaging; D049268:Positron-Emission Tomography; D014057:Tomography, X-Ray Computed
chemical_list: D019788:Fluorodeoxyglucose F18