title: [Pd(IPr*)(cinnamyl)Cl]: an efficient pre-catalyst for the preparation of tetra-ortho-substituted biaryls by Suzuki-Miyaura cross-coupling.
abstract: The bigger the better: The new well-defined [Pd(IPr*)(cin)Cl] pre-catalyst is described. This complex proves to be highly active in the Suzuki-Miyaura cross-coupling for the synthesis of tetra-ortho-substituted biaryls under mild conditions. IPr* is reported as the largest N-heterocyclic carbene (NHC) to date for [Pd(NHC)(cin)Cl] complexes, explaining the high reactivity observed for this complex in this challenging transformation.
authors.affiliation: EaStCHEM School of Chemistry, University of St Andrews, St Andrews, KY16 9ST, UK.
authors.forename: Anthony
authors.initials: A
authors.lastname: Chartoire
authors.forename: Mathieu
authors.initials: M
authors.lastname: Lesieur
authors.forename: Laura
authors.initials: L
authors.lastname: Falivene
authors.forename: Alexandra M Z
authors.initials: AM
authors.lastname: Slawin
authors.forename: Luigi
authors.initials: L
authors.lastname: Cavallo
authors.forename: Catherine S J
authors.initials: CS
authors.lastname: Cazin
authors.forename: Steven P
authors.initials: SP
authors.lastname: Nolan