title: Hyperoxia in the term newborn: more evidence is still needed for optimal oxygen therapy.
abstract: It took more than 30 years from the first observations that oxygen may be toxic during resuscitation till international guidelines changed to recommend that term and near term newborn infants should be resuscitated with air instead of 100% oxygen. There are still a number of unanswered questions related to oxygen therapy of the newborn infant. The newborn brain, lungs and other organs are susceptible to oxygen injury, and newborns still develop injury caused by hyperoxia.
authors.affiliation: Department of Pediatric Research, Clinic of Women and Child Health, Oslo University Hospital, Rikshospitalet, University of Oslo, Oslo, Norway. odsaugstad@rr-research.no
authors.forename: Ola Didrik
authors.initials: OD
authors.lastname: Saugstad
mesh_terms: D006801:Humans; D018496:Hyperoxia / Q000209:etiology / Q000503:physiopathology / Q000628:therapy*; D007231:Infant, Newborn; D010100:Oxygen / Q000009:adverse effects*; D010102:Oxygen Inhalation Therapy / Q000009:adverse effects* / Q000592:standards; D012151:Resuscitation / Q000009:adverse effects*
chemical_list: D010100:Oxygen