title: [Cephalic hypersensitivity syndrome].
abstract: The number of patients suffering from chronic headache accompanied by dizziness and cephalic ringing is gradually increasing. Pathophysiology of migraine has been commonly explained by trigeminovascular theory, although recent studies have suggested that the cause of the migraine stems from cortical hyperexcitability. We measured EEG in 1,000 patients suffering from daily headache accompanied by dizziness and cephalic ringing. Here we defined a new syndrome,"cephalic hypersensitivity syndrome" as a subliminal cortical hyperexcitability which itself is invisible but apparently seen as some symptoms such as dizziness and cephalic ringing. The cephalic hypersensitivity syndrome should be treated to attenuate the excitability by an appropriate triptan medication during attacks so as to exhibit its recurrence.
authors.affiliation: Headache Clinic, Department of Neurosurgery, Institute of Neurology, Tokyo Women's Medical University.
authors.forename: Toshihiko
authors.initials: T
authors.lastname: Shimizu
authors.forename: Koichi
authors.initials: K
authors.lastname: Hirata
authors.forename: Shinya
authors.initials: S
authors.lastname: Manaka
authors.forename: Ichiro
authors.initials: I
authors.lastname: Arakawa
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002540:Cerebral Cortex / Q000503:physiopathology*; D002908:Chronic Disease; D006801:Humans; D008875:Middle Aged; D008881:Migraine Disorders / Q000503:physiopathology*; D014012:Tinnitus / Q000503:physiopathology