title: [A case of gastric cancer treated with modified docetaxel, cisplatin and 5-fluorouracil(mDCF)with ingestion inability].
abstract: The standard regimen of S-1 and cisplatin is not adaptable for patients with gastric cancer with an ingestion inability. A 74- year-old man was revealed to have unresectable gastric cancer with severe pyloric stenosis(cT4, cN3, cH1, cP0, cStage IV). He was treated with systemic chemotherapy using modified docetaxel, cisplatin and 5-fluorouracil(mDCF). He had manageable neutropenia(grade 3 and 4)during his treatment. CT findings after 3 courses showed reduced primary tumor and metastatic lesions. A curative operation was performed based on the effective response with downstaging. Palliative surgery was considered before receiving chemotherapy. mDCF therapy is one of the recommended options for gastric cancer with an ingestion inability.
authors.affiliation: Dept. of Medical Oncology, Hirosaki University Graduate School of Medicine, Japan.
authors.forename: Atsushi
authors.initials: A
authors.lastname: Ishiguro
authors.forename: Takenori
authors.initials: T
authors.lastname: Takahata
authors.forename: Yoshifumi
authors.initials: Y
authors.lastname: Matsumoto
authors.forename: Satoshi
authors.initials: S
authors.lastname: Tanaka
authors.forename: Jugoh
authors.initials: J
authors.lastname: Itoh
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Kawasaki
authors.forename: Yasuyuki
authors.initials: Y
authors.lastname: Kudoh
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Kijima
authors.forename: Sen
authors.initials: S
authors.lastname: Shimaya
authors.forename: Yasuo
authors.initials: Y
authors.lastname: Saijo
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002945:Cisplatin / Q000008:administration & dosage; D003131:Combined Modality Therapy; D000077143:Docetaxel; D001068:Feeding and Eating Disorders / Q000209:etiology*; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D008297:Male; D009362:Neoplasm Metastasis; D009367:Neoplasm Staging; D013274:Stomach Neoplasms / Q000150:complications / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D043823:Taxoids / Q000008:administration & dosage; D014057:Tomography, X-Ray Computed
chemical_list: D043823:Taxoids; D000077143:Docetaxel; D002945:Cisplatin; D005472:Fluorouracil