title: Comparative analysis of multiparametric magnetic resonance and PET-CT in the management of local recurrence after radical prostatectomy for prostate cancer.
abstract: OBJECTIVE
  Our aim was to assess whether multiparametric magnetic resonance and PET-CT can have a role in detecting local recurrence in patients with biochemical recurrence after radical prostatectomy.
  
  
  METHODS
  We reviewed the recent international literature by carrying out a PUBMED search.
  
  
  RESULTS
  We critically reviewed 11 recent original studies about the use of PET-CT and 5 recent studies about the use of multiparametric magnetic resonance. PET-CT has not shown significant results in terms of detection rate for local recurrence in patients with low level of PSA. Multiparametric magnetic resonance showed encouraging results to detect local recurrence in patients with low PSA and with small diameter lesions.
  
  
  CONCLUSIONS
  Currently, most important urological societies do not consider multiparametric magnetic resonance and PET-CT in the follow-up of patients with suspected local recurrence after radical prostatectomy. We can assert that multiparametric magnetic resonance seems to have excellent results in detecting local recurrence in patients submitted to radical prostatectomy and PSA<1.5 ng/ml.
authors.affiliation: Department of Urology, University Sapienza, Rome, Italy.
authors.forename: Andrea
authors.initials: A
authors.lastname: Alfarone
authors.forename: Valeria
authors.initials: V
authors.lastname: Panebianco
authors.forename: Orazio
authors.initials: O
authors.lastname: Schillaci
authors.forename: Stefano
authors.initials: S
authors.lastname: Salciccia
authors.forename: Susanna
authors.initials: S
authors.lastname: Cattarino
authors.forename: Gianna
authors.initials: G
authors.lastname: Mariotti
authors.forename: Alessandro
authors.initials: A
authors.lastname: Gentilucci
authors.forename: Magnus
authors.initials: M
authors.lastname: Von Heland
authors.forename: Roberto
authors.initials: R
authors.lastname: Passariello
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Gentile
authors.forename: Alessandro
authors.initials: A
authors.lastname: Sciarra
mesh_terms: D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D064847:Multimodal Imaging; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis* / Q000000981:diagnostic imaging; D049268:Positron-Emission Tomography; D011471:Prostatic Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed