title: Intravenous recombinant tissue plasminogen activator thrombolysis in acute ischemic stroke due to middle cerebral artery dissection.
abstract: Beneficial effect of recombinant tissue plasminogen activator (rtPA) in cerebral arterial dissection is controversial. We experienced a 45-year-old man with acute ischemic stroke due to middle cerebral artery dissection, who was treated with rtPA. Characteristic vascular findings indicating dissection became evident only in subsequent angiographic examinations. Our case indicates that serial angiographic examinations should be essential after acute thrombolytic therapy, especially in young patients who are at a high risk of cerebral arterial dissection.
authors.affiliation: Department of Cerebrovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan.
authors.forename: Ryosuke
authors.initials: R
authors.lastname: Doijiri
authors.forename: Chiaki
authors.initials: C
authors.lastname: Yokota
authors.forename: Rieko
authors.initials: R
authors.lastname: Suzuki
authors.forename: Kazunori
authors.initials: K
authors.lastname: Toyoda
authors.forename: Kazuo
authors.initials: K
authors.lastname: Minematsu
mesh_terms: D000784:Aortic Dissection / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D015901:Angiography, Digital Subtraction; D002533:Cerebral Angiography / Q000379:methods; D005343:Fibrinolytic Agents / Q000008:administration & dosage*; D006801:Humans; D020244:Infarction, Middle Cerebral Artery / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology; D007262:Infusions, Intravenous; D002532:Intracranial Aneurysm / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D018810:Magnetic Resonance Angiography; D008297:Male; D008875:Middle Aged; D020768:Middle Cerebral Artery / Q000000981:diagnostic imaging / Q000473:pathology; D011994:Recombinant Proteins / Q000008:administration & dosage; D015912:Thrombolytic Therapy; D010959:Tissue Plasminogen Activator / Q000008:administration & dosage*; D016896:Treatment Outcome
chemical_list: D005343:Fibrinolytic Agents; D011994:Recombinant Proteins; D010959:Tissue Plasminogen Activator