title: Regulation of TGF-β receptor activity.
abstract: TGF-β signaling regulates diverse cellular processes, including cell proliferation, differentiation, apoptosis, cell plasticity and migration. Its dysfunctions can result in various kinds of diseases, such as cancer and tissue fibrosis. TGF-β signaling is tightly regulated at different levels along the pathway, and modulation of TGF-β receptor activity is a critical step for signaling regulation. This review focuses on our recent understanding of regulation of TGF-β receptor activity.
authors.affiliation: The State Key Laboratory of Biomembrane and Membrane Biotechnology, THU-PKU Joint Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, 100084, China. ygchen@tsinghua.edu.cn.
authors.forename: Fei
authors.initials: F
authors.lastname: Huang
authors.forename: Ye-Guang
authors.initials: YG
authors.lastname: Chen