title: Lower serum interleukin-2 levels in schizophrenic patients with tardive dyskinesia.
abstract: We determined serum interleukin-2 (IL-2) levels between schizophrenic patients with (n=45) and without tardive dyskinesia (TD; n=45) compared to normal controls (n=50). TD patients had lower serum IL-2 levels than non-TD patients, but higher IL-2 levels than normal controls. IL-2 was associated with the negative symptoms of schizophrenia, but not with TD severity. Immune disturbance may be involved in the pathophysiology of TD.
authors.affiliation: Inner Mongolia Medical College, Hohhot, PR China.
authors.forename: Haibo
authors.initials: H
authors.lastname: Liu
authors.forename: Yimin
authors.initials: Y
authors.lastname: Kang
authors.forename: Jun
authors.initials: J
authors.lastname: Liang
authors.forename: Cunbao
authors.initials: C
authors.lastname: Li
authors.forename: Meihong
authors.initials: M
authors.lastname: Xiu
authors.forename: Dachun
authors.initials: D
authors.lastname: Chen
authors.forename: Fude
authors.initials: F
authors.lastname: Yang
authors.forename: Fang
authors.initials: F
authors.lastname: Wang
authors.forename: Guiying
authors.initials: G
authors.lastname: Wu
authors.forename: Colin N
authors.initials: CN
authors.lastname: Haile
authors.forename: Therese A
authors.initials: TA
authors.lastname: Kosten
authors.forename: Thomas R
authors.initials: TR
authors.lastname: Kosten
authors.forename: Xiang Yang
authors.initials: XY
authors.lastname: Zhang
mesh_terms: D016022:Case-Control Studies; D005260:Female; D006801:Humans; D007376:Interleukin-2 / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D009069:Movement Disorders / Q000097:blood* / Q000150:complications / Q000175:diagnosis; D012559:Schizophrenia / Q000097:blood* / Q000150:complications / Q000175:diagnosis; D012720:Severity of Illness Index
chemical_list: D007376:Interleukin-2