title: Candidal mediastinitis successfully treated using vacuum-assisted closure following open-heart surgery.
abstract: Deep sternal wound infections (DSWIs) are an uncommon but serious complication after open-heart surgery. The reported incidence of DSWIs due to Candida albicans is 0.4%, but these infections have an extremely high mortality of 56%. We herein report a rare case of a 79-year old woman who suffered from Candidal DSWI after repeated open-heart surgeries. We treated her with negative pressure wound therapy (NPWT). This is the rare case report that provides evidence that NPWT is a safe and suitable technique for the management of Candidal DSWIs.
authors.affiliation: Department of Cardiovascular Surgery, Mitsubishi Kyoto Hospital, Kyoto, Japan. osahiro@kuhp.kyoto-u.ac.jp
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Osada
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Nakajima
authors.forename: Manabu
authors.initials: M
authors.lastname: Morishima
authors.forename: Takamitsu
authors.initials: T
authors.lastname: Su
mesh_terms: D000368:Aged; D000935:Antifungal Agents / Q000627:therapeutic use; D002177:Candidiasis / Q000382:microbiology / Q000628:therapy*; D006348:Cardiac Surgical Procedures / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008480:Mediastinitis / Q000382:microbiology / Q000628:therapy*; D054843:Negative-Pressure Wound Therapy; D012086:Reoperation; D013530:Surgical Wound Infection / Q000382:microbiology / Q000628:therapy*; D016896:Treatment Outcome
chemical_list: D000935:Antifungal Agents