title: Emerging roles for biomaterials in the treatment of liver disease.
abstract: This review explores potential roles for biomaterials in the field of liver surgery and hepatology. The studies reviewed are presented in three sections. The first section discusses liver regeneration and strategies to modulate it. The second section outlines the pathophysiology of liver inflammation and fibrosis and highlights novel therapeutic targets. The final section summarises the current challenges in liver surgery and discusses how biomaterials may be used to address these challenges and focuses on early translational applications for biomaterials for drug delivery and liver surgery.
authors.affiliation: Division of Gastrointestinal Surgery, Nottingham Digestive Diseases Centre NIHR Biomedical Research Unit, Nottingham University Hospitals, Queen's Medical Centre, Nottingham NG7 2UH, UK. john.hammond@nottingham.ac.uk
authors.forename: John S
authors.initials: JS
authors.lastname: Hammond
authors.forename: Dileep N
authors.initials: DN
authors.lastname: Lobo
mesh_terms: D001672:Biocompatible Materials / Q000627:therapeutic use*; D003952:Diagnostic Imaging; D015316:Genetic Therapy; D006801:Humans; D008099:Liver / Q000187:drug effects / Q000473:pathology / Q000601:surgery; D008107:Liver Diseases / Q000188:drug therapy / Q000628:therapy*; D008115:Liver Regeneration / Q000187:drug effects
chemical_list: D001672:Biocompatible Materials