title: Biomimetic sensing based on chemically induced assembly of a signaling DNA aptamer on a fluid bilayer membrane.
abstract: The adenosine aptamer was split into two halves and linked to a fluid liposome surface; addition of adenosine resulted in aptamer assembly, which did not occur if the split aptamer was attached to silica nanoparticles, demonstrating the feasibility of using aptamer probes to study diffusion within lipid membranes.
authors.affiliation: Department of Chemistry, Waterloo Institute for Nanotechnology, University of Waterloo, Waterloo, Ontario, N2L 3G1, Canada.
authors.forename: Neeshma
authors.initials: N
authors.lastname: Dave
authors.forename: Juewen
authors.initials: J
authors.lastname: Liu
mesh_terms: D000241:Adenosine / Q000737:chemistry; D000255:Adenosine Triphosphate / Q000737:chemistry; D052157:Aptamers, Nucleotide / Q000737:chemistry*; D032701:Biomimetics; D015374:Biosensing Techniques; D008081:Liposomes / Q000737:chemistry*; D053758:Nanoparticles / Q000737:chemistry; D012822:Silicon Dioxide / Q000737:chemistry
chemical_list: D052157:Aptamers, Nucleotide; D008081:Liposomes; D012822:Silicon Dioxide; D000255:Adenosine Triphosphate; D000241:Adenosine