title: Adjunctive use of tetracycline fibers with nonsurgical periodontal therapy in an adult with Down syndrome: a case report.
abstract: Individuals with Down syndrome (DS) are susceptible to severe periodontal disease, due to immune alterations related to functional defects of polymorphonuclear leukocytes and monocytes. The adjunctive use of locally delivered antimicrobials has been proven to be beneficial, especially in areas where mechanical therapy might fail. This article describes the management of a patient with DS who had aggressive periodontitis. The treatment used a local drug delivery system with tetracycline fibers as an adjunct to scaling and root planing.
authors.affiliation: Faculty of Periodontology Professor, Vishnu Dental College, Bhimavaram, AP, India. drpsgautami@gmail.com
authors.forename: Penmetsa Subadhra
authors.initials: PS
authors.lastname: Gautami
authors.forename: Alluri Venkata
authors.initials: AV
authors.lastname: Ramaraju
authors.forename: Madiraju
authors.initials: M
authors.lastname: Gunashekhar
mesh_terms: D000328:Adult; D010520:Aggressive Periodontitis / Q000188:drug therapy* / Q000628:therapy; D016301:Alveolar Bone Loss / Q000188:drug therapy / Q000628:therapy; D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D003094:Collagen; D003131:Combined Modality Therapy; D003774:Dental Plaque Index; D012534:Dental Scaling / Q000379:methods; D004314:Down Syndrome / Q000150:complications*; D004337:Drug Carriers; D016503:Drug Delivery Systems; D005260:Female; D005500:Follow-Up Studies; D017823:Furcation Defects / Q000188:drug therapy / Q000628:therapy; D006801:Humans; D017622:Periodontal Attachment Loss / Q000188:drug therapy / Q000628:therapy; D010512:Periodontal Index; D010514:Periodontal Pocket / Q000188:drug therapy / Q000628:therapy; D016745:Root Planing / Q000379:methods; D013752:Tetracycline / Q000008:administration & dosage*; D014086:Tooth Mobility / Q000188:drug therapy / Q000628:therapy
chemical_list: D000900:Anti-Bacterial Agents; D004337:Drug Carriers; D003094:Collagen; D013752:Tetracycline