title: Ophthalmic changes in severe anorexia nervosa: a case series.
abstract: OBJECTIVE
  We describe the diagnosis and management of lagophthalmos, or failure of eyelid closure, in five patients with severe anorexia nervosa (AN) who complained of dry, irritated eyes and photophobia.
  
  
  METHODS
  Five patients with these findings are described retrospectively.
  
  
  RESULTS
  Examination revealed lagopthalmos in the setting of ptosis and enophthalmos, with multiple other starvation-mediated medical complications.
  
  
  CONCLUSIONS
  These eye findings, as complications of AN, have not been described in the literature. With careful protective measures, initiation of nutritional rehabilitation, and intensively monitored early refeeding, these patients' ocular abnormalities and associated symptoms resolved completely. Recognition of this pathology and appropriate management can prevent long-term morbidity in the form of permanent loss of visual acuity due to corneal abrasions and improve the outcomes for these patients with severe AN.
authors.affiliation: ACUTE Center for Eating Disorders, Denver Health Medical Center, Denver, CO, USA. jennifer.gaudiani@dhha.org
authors.forename: Jennifer L
authors.initials: JL
authors.lastname: Gaudiani
authors.forename: Jon M
authors.initials: JM
authors.lastname: Braverman
authors.forename: Margherita
authors.initials: M
authors.lastname: Mascolo
authors.forename: Philip S
authors.initials: PS
authors.lastname: Mehler
mesh_terms: D000328:Adult; D000856:Anorexia Nervosa / Q000150:complications*; D005128:Eye Diseases / Q000209:etiology*; D005141:Eyelid Diseases / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D005260:Female; D006801:Humans; D020795:Photophobia / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D012189:Retrospective Studies; D014792:Visual Acuity