title: Copper-catalyzed alkylation of benzoxazoles with secondary alkyl halides.
abstract: Copper-catalyzed direct alkylation of benzoxazoles using nonactivated secondary alkyl halides has been developed. The best catalyst is a new copper(I) complex (1), and the reactions are promoted by bis[2-(N,N-dimethylamino)ethyl] ether.
authors.affiliation: Laboratory of Inorganic Synthesis and Catalysis, Institute of Chemical Sciences and Engineering, Ecole Polytechnique Fédérale de Lausanne, SB-ISIC-LSCI, BCH 3305, Lausanne 1015, Switzerland.
authors.forename: Peng
authors.initials: P
authors.lastname: Ren
authors.forename: Isuf
authors.initials: I
authors.lastname: Salihu
authors.forename: Rosario
authors.initials: R
authors.lastname: Scopelliti
authors.forename: Xile
authors.initials: X
authors.lastname: Hu
mesh_terms: D000478:Alkylation; D001583:Benzoxazoles / Q000737:chemistry*; D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D003300:Copper / Q000737:chemistry*; D006846:Hydrocarbons, Halogenated / Q000737:chemistry*; D015394:Molecular Structure
chemical_list: D001583:Benzoxazoles; D006846:Hydrocarbons, Halogenated; D003300:Copper