title: The role of renin angiotensin system intervention in stage B heart failure.
abstract: This article outlines the link between the renin angiotensin aldosterone system (RAAS) and various forms of cardiomyopathy, and also reviews the understanding of the effectiveness of RAAS intervention in this phase of ventricular dysfunction. The authors focus their discussion predominantly on patients who have had previous myocardial infarction or those who have left ventricular hypertrophy and also briefly discuss the role of RAAS activation and intervention in patients with alcoholic cardiomyopathy.
authors.affiliation: Heart Failure Unit, St Vincent's University Hospital, Elm Park, Dublin 4, Ireland.
authors.forename: Patrick
authors.initials: P
authors.lastname: Collier
authors.forename: Kenneth M
authors.initials: KM
authors.lastname: McDonald
mesh_terms: D000804:Angiotensin II / Q000187:drug effects / Q000502:physiology; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use; D000818:Animals; D003925:Diabetic Angiopathies / Q000503:physiopathology; D006333:Heart Failure / Q000188:drug therapy / Q000209:etiology / Q000503:physiopathology*; D006801:Humans; D009203:Myocardial Infarction / Q000150:complications; D017202:Myocardial Ischemia / Q000503:physiopathology; D012084:Renin-Angiotensin System / Q000502:physiology*; D015398:Signal Transduction / Q000502:physiology; D013318:Stroke Volume / Q000502:physiology; D018487:Ventricular Dysfunction, Left / Q000503:physiopathology*
chemical_list: D000806:Angiotensin-Converting Enzyme Inhibitors; D000804:Angiotensin II