title: [Association of Helicobacter pylori infection and serum homocysteine level in patients with cerebral infarction].
abstract: To investigate the association of Helicobacter pylori infection and serum homocysteine(Hcy) levels with acute cerebral infarction.
  
  
  
  Serum Hp-IgG, Hp-CagA-IgG and Hcy were detected by biological micro-array analysis system in 85 patients with acute cerebral infarction and 40 healthy subjects (control group).
  
  
  
  The positive rates of Hp-IgG and Hp-CagA-IgG significantly increased in cerebral infarction group compared with controls (P<0.05). There were significant differences in serum Hcy level between Hp-CagA-IgG positive and negative patients (P<0.05), but not between Hp-IgG positive and negative patients (P>0.05).
  
  
  
  CagA-positive Hp infection may increase the risk of cerebral infarction, which might be associated with the increased serum homocysteine level.
authors.affiliation: Department of Neurology, The Second Affiliated Hospital, Medical College of Xi'an Jiaotong University, Xi'an 710004, China. whq60@sohu.com
authors.forename: Hai-qin
authors.initials: HQ
authors.lastname: Wu
authors.forename: Xin
authors.initials: X
authors.lastname: Zhang
authors.forename: Yan
authors.initials: Y
authors.lastname: Tang
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002544:Cerebral Infarction / Q000097:blood* / Q000150:complications; D005260:Female; D016481:Helicobacter Infections / Q000097:blood* / Q000150:complications; D016480:Helicobacter pylori; D006710:Homocysteine / Q000097:blood*; D006801:Humans; D008297:Male; D008875:Middle Aged
chemical_list: D006710:Homocysteine