title: The Over-The-Scope-Clip (OTSC) system is effective in the treatment of chronic esophagojejunal anastomotic leakage.
abstract: BACKGROUND
  Management of postoperative esophagojejunal anastomotic leakage after total gastrectomy represents a very challenging event. Surgical repair is difficult, and conservative treatment can predispose to more severe complications. Endoclips and self-expanding stents are useful endoscopic therapeutic options but present some drawbacks. The Over-The-Scope-Clip (OTSC) system has been shown to be appropriate to close acute small gastrointestinal perforations, but its use in the treatment of chronic leakage remains controversial.
  
  
  METHODS
  The present series reports three consecutive chronic esophagojejunal anastomotic leaks successfully treated with OTSC. In all cases, clip application was simple, safe and effective, without early and late complications.
  
  
  CONCLUSIONS
  The OTSC system may represent a new therapeutic option in the management of postoperative esophagojejunal anastomotic leakage.
authors.affiliation: Division of Surgical Oncology-"F. Magrassi-A. Lanzara" Department of Clinical and Experimental Medicine and Surgery, Second University of Naples School of Medicine, c/o II Policlinico, Edificio 17, Via Pansini 5, 80131 Naples, Italy. gennaro.galizia@unina2.it
authors.forename: Gennaro
authors.initials: G
authors.lastname: Galizia
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Napolitano
authors.forename: Paolo
authors.initials: P
authors.lastname: Castellano
authors.forename: Margherita
authors.initials: M
authors.lastname: Pinto
authors.forename: Anna
authors.initials: A
authors.lastname: Zamboli
authors.forename: Pietro
authors.initials: P
authors.lastname: Schettino
authors.forename: Michele
authors.initials: M
authors.lastname: Orditura
authors.forename: Ferdinando
authors.initials: F
authors.lastname: De Vita
authors.forename: Annamaria
authors.initials: A
authors.lastname: Auricchio
authors.forename: Andrea
authors.initials: A
authors.lastname: Mabilia
authors.forename: Angelo
authors.initials: A
authors.lastname: Pezzullo
authors.forename: Eva
authors.initials: E
authors.lastname: Lieto
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000714:Anastomosis, Surgical; D057868:Anastomotic Leak / Q000601:surgery*; D002908:Chronic Disease; D016099:Endoscopy, Gastrointestinal; D004947:Esophagus / Q000601:surgery*; D005743:Gastrectomy; D006801:Humans; D007583:Jejunum / Q000601:surgery*; D008297:Male; D058106:Wound Closure Techniques / Q000295:instrumentation*