title: Antibacterial activity of a new mineral trioxide aggregate-based root canal sealer.
abstract: OBJECTIVE
  To compare the antibacterial effect of AH-26, white-coloured mineral trioxide aggregate (WMTA) and CPM sealer against Staphylococcus aureus and Streptococcus mutans after 24 h and 1 week.
  
  
  METHODS
  All materials were prepared according to the manufacturers' directions immediately before testing. The antibacterial effect of each agent was determined by measuring the diameter of the zone of inhibition in millimetres after incubation at 37°C for 24 h and 7 days in a humid atmosphere. Each test was repeated three times.
  
  
  RESULTS
  In the 24-h and 7-day samples, the antibacterial activity of AH-26 was significantly greater than that of the two other materials tested against both bacteria (P < 0.05). The antibacterial activities of CPM sealer and WMTA against S. aureus were not significantly different (P > 0.05) in 24-h or 7-day samples, but CPM sealer demonstrated a significantly greater effect than WMTA against S. mutans (P < 0.05).
  
  
  CONCLUSIONS
  All products studied exhibited antibacterial activity. However, in 24-h and 7-day samples, AH-26 exerted the greatest activity against both organisms tested.
authors.affiliation: Department of Endodontics, Hamedan University of Medical Sciences, Iran. zahed_mohammadi@yahoo.com
authors.forename: Zahed
authors.initials: Z
authors.lastname: Mohammadi
authors.forename: Luciano
authors.initials: L
authors.lastname: Giardino
authors.forename: Flavio
authors.initials: F
authors.lastname: Palazzi
authors.forename: Sousan
authors.initials: S
authors.lastname: Shalavi
mesh_terms: D017607:Aluminum Compounds / Q000032:analysis / Q000494:pharmacology*; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001729:Bismuth / Q000494:pharmacology; D002122:Calcium Chloride / Q000032:analysis; D017610:Calcium Compounds / Q000032:analysis / Q000494:pharmacology*; D004338:Drug Combinations; D004853:Epoxy Resins / Q000494:pharmacology; D006801:Humans; D006813:Humidity; D008422:Materials Testing; D010087:Oxides / Q000032:analysis / Q000494:pharmacology*; D012387:Root Canal Filling Materials / Q000032:analysis / Q000494:pharmacology*; D017640:Silicates / Q000032:analysis / Q000494:pharmacology*; D012834:Silver / Q000494:pharmacology; D013211:Staphylococcus aureus / Q000187:drug effects; D013295:Streptococcus mutans / Q000187:drug effects; D013696:Temperature; D013997:Time Factors; D014025:Titanium / Q000494:pharmacology
chemical_list: D017607:Aluminum Compounds; D000900:Anti-Bacterial Agents; D017610:Calcium Compounds; D004338:Drug Combinations; D004853:Epoxy Resins; D010087:Oxides; D012387:Root Canal Filling Materials; D017640:Silicates; C086631:mineral trioxide aggregate; C035219:calcium aluminate; D012834:Silver; C506393:tricalcium silicate; C028044:epoxy resin AH-26; C016538:lime; D014025:Titanium; D002122:Calcium Chloride; D001729:Bismuth