title: Highly efficient synthesis of N-substituted isoindolinones and phthalazinones using Pt nanowires as catalysts.
abstract: A series of N-substituted isoindolinones have been successfully synthesized through the reductive C-N coupling and intramolecular amidation of 2-carboxybenzaldehyde and amines. This one-pot synthesis gives excellent yields using ultrathin Pt nanowires as catalysts under 1 bar of hydrogen. These unsupported catalysts can also be used for the synthesis of phthalazinones in high yield when hydrazine or phenyl hydrazine is used instead of amines.
authors.affiliation: Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou 215123, China.
authors.forename: Linyan
authors.initials: L
authors.lastname: Shi
authors.forename: Lei
authors.initials: L
authors.lastname: Hu
authors.forename: Jiaqing
authors.initials: J
authors.lastname: Wang
authors.forename: Xueqin
authors.initials: X
authors.lastname: Cao
authors.forename: Hongwei
authors.initials: H
authors.lastname: Gu
mesh_terms: D000588:Amines / Q000737:chemistry; D002384:Catalysis; D054833:Isoindoles / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D053770:Nanowires / Q000737:chemistry*; D010793:Phthalazines / Q000138:chemical synthesis* / Q000737:chemistry; D010984:Platinum / Q000737:chemistry*
chemical_list: D000588:Amines; D054833:Isoindoles; D010793:Phthalazines; D010984:Platinum