title: Sarcopenia in the elderly.
abstract: Sarcopenia is the age-related loss of muscle. It leads to loss of muscle power, which in the end results in frailty and disability. There are numerous causes of sarcopenia. Treatment consists of resistance exercise and a leucine-enriched essential amino acid protein supplement. There is an emerging role for testosterone and other anabolic steroids. An activin II receptor soluble fusion protein is showing great potential to increase muscle mass and bone mineral density.
authors.affiliation: Geriatric Research, Education and Clinical Center (GRECC), Veterans Affairs Medical Center and Department of Internal Medicine, Division of Geriatric Medicine, Saint Louis University School of Medicine, St Louis, MO, USA. morley@slu.edu
authors.forename: John E
authors.initials: JE
authors.lastname: Morley
mesh_terms: D000368:Aged; D000375:Aging / Q000502:physiology; D016330:Frail Elderly; D015577:Geriatric Assessment; D006801:Humans; D053580:Muscle Strength; D055948:Sarcopenia / Q000175:diagnosis / Q000453:epidemiology / Q000503:physiopathology* / Q000628:therapy; D013739:Testosterone / Q000502:physiology
chemical_list: D013739:Testosterone