title: Rare form of semi-invasive aspergillosis in immunocompetent patient: case report.
abstract: Chronic necrotizing or semi-invasive aspergillosis represents a disease commonly occurred in patients with mild immunodeficiency. We report a case of chronic necrotizing pulmonary aspergillosis in immunocompetent patient without underlying disease. The discovery of the disease was made accidentally, by finding a nodular opacity on a routine chest X-ray. The diagnostic was confirmed by pathological and bacteriological examination. With specific antifungal treatment, no complete eradication was obtained and the patient has a slow evolution with many relapses.
authors.affiliation: National Institute of Pneumology, Bucharest, Romania. haulicaalina@yahoo.com
authors.forename: Alina
authors.initials: A
authors.lastname: Croitoru
authors.forename: Boris
authors.initials: B
authors.lastname: Melloni
authors.forename: Magali
authors.initials: M
authors.lastname: Dupuy-Grasset
authors.forename: M L
authors.initials: ML
authors.lastname: Darde
authors.forename: Manuela
authors.initials: M
authors.lastname: Delage
authors.forename: Francois
authors.initials: F
authors.lastname: Bonnaud
mesh_terms: D000328:Adult; D000935:Antifungal Agents / Q000627:therapeutic use*; D000077336:Caspofungin; D003937:Diagnosis, Differential; D004359:Drug Therapy, Combination; D054714:Echinocandins / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007121:Immunocompetence; D033162:Incidental Findings; D055744:Invasive Pulmonary Aspergillosis / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D017964:Itraconazole / Q000627:therapeutic use; D055666:Lipopeptides; D011379:Prognosis; D011743:Pyrimidines / Q000627:therapeutic use; D011859:Radiography; D035583:Rare Diseases; D012008:Recurrence; D020775:Thoracic Surgery, Video-Assisted; D013997:Time Factors; D016896:Treatment Outcome; D014230:Triazoles / Q000627:therapeutic use; D065819:Voriconazole
chemical_list: D000935:Antifungal Agents; D054714:Echinocandins; D055666:Lipopeptides; D011743:Pyrimidines; D014230:Triazoles; D017964:Itraconazole; D000077336:Caspofungin; D065819:Voriconazole