title: Moving towards a comprehensive assessment of lower urinary tract symptoms (LUTS).
abstract: OBJECTIVE
  To evaluate the utility of the International Prostate Symptom Score (IPSS) and the LUTS Tool when assessing lower urinary tract symptoms (LUTS). Secondary objectives were to examine associations of LUTS and treatment seeking.
  
  
  METHODS
  Analyses were performed using EpiLUTS data, a population-based, cross-sectional, Internet survey of men and women (aged ≥40) in Sweden, UK, and US with a sample of 30,000 participants. Participants completed the IPSS and the LUTS Tool. Prevalence rates of symptoms captured by the LUTS Tool were compared using IPSS summary scores: 0, 1-7, 8-19, and ≥20. LUTS Tool subscale scores were calculated. Pearson correlations between the LUTS Tool symptoms and subscales and IPSS symptoms were performed. Logistic regressions evaluated the associations of IPSS scores and LUTS Tool subscales with treatment seeking for LUTS.
  
  
  RESULTS
  The IPSS did not assess some symptoms (i.e., incontinence) for which there was a high prevalence among participants. Correlations between the 7 symptoms assessed by the IPSS and LUTS Tool were moderate to high ranging between 0.37 (nocturia women) and 0.77 (weak stream men), indicating concordance. While the LUTS Tool subscales and the total IPSS score were all significantly associated with treatment seeking, the LUTS Tool OAB subscale in men and Voiding subscale in women most strongly predicted treatment seeking.
  
  
  CONCLUSIONS
  LUTS that are excluded from the IPSS, most notably incontinence, were prevalent even among mildly symptomatic participants. Since storage symptoms appear to drive treatment seeking, identifying, and treating these symptoms is essential when caring for patients with LUTS.
authors.affiliation: United BioSource Corporation, Bethesda, MD, USA. karin.coyne@unitedbiosource.com
authors.forename: Karin S
authors.initials: KS
authors.lastname: Coyne
authors.forename: Alexandra I
authors.initials: AI
authors.lastname: Barsdorf
authors.forename: Christine
authors.initials: C
authors.lastname: Thompson
authors.forename: Andrea
authors.initials: A
authors.lastname: Ireland
authors.forename: Ian
authors.initials: I
authors.lastname: Milsom
authors.forename: Chris
authors.initials: C
authors.lastname: Chapple
authors.forename: Zoe S
authors.initials: ZS
authors.lastname: Kopp
authors.forename: Tamara
authors.initials: T
authors.lastname: Bavendam
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003430:Cross-Sectional Studies; D005260:Female; D006306:Health Surveys; D006801:Humans; D059411:Lower Urinary Tract Symptoms / Q000175:diagnosis* / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D011788:Quality of Life; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires; D013548:Sweden / Q000453:epidemiology; D014554:Urination / Q000502:physiology; D014555:Urination Disorders / Q000175:diagnosis* / Q000453:epidemiology