title: Electrophilicity of α-oxo gold carbene intermediates: halogen abstractions from halogenated solvents leading to the formation of chloro/bromomethyl ketones.
abstract: α-Oxo gold carbenes generated via intermolecular oxidation of terminal alkynes are shown to be highly electrophilic and can effectively abstract halogen from halogenated solvents such as 1,2-dichloroethane or 1,2-dibromoethane. Chloro/bromomethyl ketones are prepared in moderate efficiencies in one step using Ph(3)PAuNTf(2) as the catalyst and 8-methylquinoline N-oxide as the oxidant.
authors.affiliation: College of Chemistry and Chemical Engineering, State Key Laboratory of Chemo/Biosensing and Chemometrics, Hunan University, Changsha, 410082, PR of China.
authors.forename: Weimin
authors.initials: W
authors.lastname: He
authors.forename: Longyong
authors.initials: L
authors.lastname: Xie
authors.forename: Yingying
authors.initials: Y
authors.lastname: Xu
authors.forename: Jiannan
authors.initials: J
authors.lastname: Xiang
authors.forename: Liming
authors.initials: L
authors.lastname: Zhang