title: Further comments on the induction of lung tumors by plutonium dioxide in beagles.
abstract: A series of recent papers describes the final results obtained from studies of the effects of inhaled plutonium dioxide on beagle dogs. This note considers the value of a microdosimetric assessment of these data. In particular, it offers support for the existence of a threshold for the induction of lung tumors.
authors.forename: J A
authors.initials: JA
authors.lastname: Simmons
authors.forename: S R
authors.initials: SR
authors.lastname: Richards
mesh_terms: D000336:Aerosols / Q000633:toxicity*; D000818:Animals; D002273:Carcinogens / Q000633:toxicity*; D005260:Female; D006706:Homeostasis / Q000528:radiation effects*; D008175:Lung Neoplasms / Q000139:chemically induced*; D008297:Male; D009381:Neoplasms, Radiation-Induced / Q000139:chemically induced*; D011005:Plutonium / Q000633:toxicity*
chemical_list: D000336:Aerosols; D002273:Carcinogens; D011005:Plutonium