title: Spontaneous coronary artery dissection during cabergoline therapy.
abstract: Although spontaneous coronary artery dissection is a rare cause of acute coronary syndrome, it should be considered during the evaluation of patients who have chest pain. Coronary vasospasm can lead to spontaneous dissection. The dopamine agonist cabergoline is known to cause digital vasospasm. Herein, we report a case of spontaneous right coronary artery dissection in a 43-year-old woman who was taking cabergoline as therapy for prolactinoma. To our knowledge, this is the first report of an apparent relationship between cabergoline therapy and spontaneous coronary artery dissection. The possible association of cabergoline with coronary artery spasm and dissection should be considered in patients who present with chest pain while taking this medication.
authors.affiliation: Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA. nishaki@gmail.com
authors.forename: Nishaki Kiran
authors.initials: NK
authors.lastname: Mehta
authors.forename: Samir
authors.initials: S
authors.lastname: Malkani
authors.forename: Ira
authors.initials: I
authors.lastname: Ockene
mesh_terms: D000328:Adult; D000784:Aortic Dissection / Q000139:chemically induced* / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000503:physiopathology; D000787:Angina Pectoris / Q000139:chemically induced; D018931:Antineoplastic Agents, Hormonal / Q000009:adverse effects*; D000077465:Cabergoline; D002317:Cardiovascular Agents / Q000627:therapeutic use; D003323:Coronary Aneurysm / Q000139:chemically induced* / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000503:physiopathology; D017023:Coronary Angiography; D003329:Coronary Vasospasm / Q000139:chemically induced* / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000503:physiopathology; D004873:Ergolines / Q000009:adverse effects*; D005260:Female; D006801:Humans; D010911:Pituitary Neoplasms / Q000188:drug therapy*; D011237:Predictive Value of Tests; D015175:Prolactinoma / Q000188:drug therapy*; D012008:Recurrence; D012307:Risk Factors; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D018931:Antineoplastic Agents, Hormonal; D002317:Cardiovascular Agents; D004873:Ergolines; D000077465:Cabergoline