title: A novel conjugate of a cell-penetrating peptide and a ferrocenyl amino acid: a potential electrochemical sensor for living cells?
abstract: The conjugation of a ferrocenyl amino acid to the cell-penetrating peptide hCT(9-32) does not impair its ability to efficiently translocate into cells. Furthermore, the bioconjugate does not induce any cytotoxicity, thus presenting a potential electrochemical sensor suitable for the detection of living cells.
authors.affiliation: Translational Centre for Regenerative Medicine, Leipzig, Germany. jhoyer@uni-leipzig.de
authors.forename: Jan
authors.initials: J
authors.lastname: Hoyer
authors.forename: Andrea
authors.initials: A
authors.lastname: Hunold
authors.forename: Hans-Günther
authors.initials: HG
authors.lastname: Schmalz
authors.forename: Ines
authors.initials: I
authors.lastname: Neundorf
mesh_terms: D000596:Amino Acids / Q000737:chemistry* / Q000378:metabolism*; D015374:Biosensing Techniques / Q000379:methods*; D002470:Cell Survival; D057846:Cell-Penetrating Peptides / Q000378:metabolism*; D004563:Electrochemistry; D005296:Ferrous Compounds / Q000737:chemistry*; D006367:HeLa Cells; D006801:Humans; D000075163:Metallocenes
chemical_list: D000596:Amino Acids; D057846:Cell-Penetrating Peptides; D005296:Ferrous Compounds; D000075163:Metallocenes; C004998:ferrocene