title: [Phosphate nephropathy: how to avoid it?].
abstract: Colonoscopy is a commonly used procedure for colon cancer screening. The ideal bowel preparation for a good visualization of the colonic mucosa would be effective and well tolerated. Sodium phosphate (NaP) and polyethylen glycol (PEG) are the two most frequently used solutions in this indication. However, although NaP has been described as more effective and better tolerated, it can cause severe acute electrolytes disturbances and, in rare cases, lead to irreversible renal failure, called phosphate nephropathy. NaP should therefore be prescribed with caution and be formally banned for patients with risk factors.
authors.affiliation: Service de néphrologie, HUG, Genève. vincentbourquin@mac.com
authors.forename: Vincent
authors.initials: V
authors.lastname: Bourquin
authors.forename: Belén
authors.initials: B
authors.lastname: Ponte
authors.forename: Michael
authors.initials: M
authors.lastname: Zellweger
authors.forename: Marc
authors.initials: M
authors.lastname: Levy
authors.forename: Antoine
authors.initials: A
authors.lastname: Hadengue
authors.forename: Solange
authors.initials: S
authors.lastname: Moll
mesh_terms: D000368:Aged; D001706:Biopsy; D002400:Cathartics / Q000009:adverse effects; D003113:Colonoscopy / Q000379:methods; D005260:Female; D006801:Humans; D007674:Kidney Diseases / Q000139:chemically induced* / Q000453:epidemiology / Q000473:pathology / Q000517:prevention & control*; D010710:Phosphates / Q000009:adverse effects*; D013557:Switzerland
chemical_list: D002400:Cathartics; D010710:Phosphates; C018279:sodium phosphate