title: Orthodontic treatment of a child with Crigler-Najjar syndrome type I using tacrolimus following liver transplantation.
abstract: The present study reports the orthodontic treatment of a child with Crigler-Najjar syndrome type I following a liver transplant and administration of tacrolimus (1 mg/day). Tacrolimus (FK506) is fundamental to immunosuppression following transplantation. The child exhibited Class II division 1 malocclusion. The treatment option was to use a Herbst appliance for seven months and a fixed appliance (straight wire) for 12 months.
authors.affiliation: Department of Oral Surgery and Pathology, Faculty of Dentistry, Federal University of Minas Gerais, Belo Horizonte, Brazil.
authors.forename: Joao Batista
authors.initials: JB
authors.lastname: Novaes-Junior
authors.forename: Milene T
authors.initials: MT
authors.lastname: Martins
authors.forename: Elizabeth M
authors.initials: EM
authors.lastname: Lages
authors.forename: Miriam P
authors.initials: MP
authors.lastname: Vale
authors.forename: Henrique
authors.initials: H
authors.lastname: Pretti
authors.forename: Saul M
authors.initials: SM
authors.lastname: Paiva
mesh_terms: D002508:Cephalometry; D002648:Child; D003414:Crigler-Najjar Syndrome / Q000601:surgery*; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D016031:Liver Transplantation; D008297:Male; D008312:Malocclusion, Angle Class II / Q000628:therapy*; D017289:Orthodontic Appliances, Functional; D009969:Orthodontic Wires; D009971:Orthodontics, Corrective; D011862:Radiography, Panoramic; D063173:Retrognathia / Q000628:therapy; D016559:Tacrolimus / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D007166:Immunosuppressive Agents; D016559:Tacrolimus