title: Posterolateral spondylodesis using bioactive glass S53P4 and autogenous bone in instrumented unstable lumbar spine burst fractures. A prospective 10-year follow-up study.
abstract: OBJECTIVE
  A prospective long-term follow-up study of bioactive glass (BAG)-S53P4 and autogenous bone (AB) used as bone graft substitutes for posterolateral spondylodesis in treatment of unstable lumbar spine burst fractures during 1996-1998 was conducted.
  
  
  METHODS
  The lumbar fractures were fixed using posterior USS instrumentation. BAG was implanted on the left side of the fusion-bed and AB on the right side. The operative outcome was evaluated on X-rays and CT scans, and a clinical examination was also performed.
  
  
  RESULTS
  The Oswestry score was excellent, and the mean pain score 1. The mean compression rate of the injured vertebral body was 25%. A solid bony fusion was seen on CT scans on the AB side in all patients and on the BAG side in five patients, and a partial fusion in five patients, resulting in a total fusion-rate of 71% of all fused segments in the BAG group.
  
  
  CONCLUSIONS
  Our long-term results show that BAG-S54P4 bone graft material is safe to be used as a bone graft extender in spine surgery.
authors.affiliation: Department of Orthopaedic Surgery and Traumatology, Turku University Hospital, University of Turku, Turku, Finland. juho.rantakokko@tyks.fi
authors.forename: J
authors.initials: J
authors.lastname: Rantakokko
authors.forename: J P
authors.initials: JP
authors.lastname: Frantzén
authors.forename: J
authors.initials: J
authors.lastname: Heinänen
authors.forename: S
authors.initials: S
authors.lastname: Kajander
authors.forename: E
authors.initials: E
authors.lastname: Kotilainen
authors.forename: E
authors.initials: E
authors.lastname: Gullichsen
authors.forename: N C
authors.initials: NC
authors.lastname: Lindfors
mesh_terms: D000328:Adult; D018786:Bone Substitutes / Q000627:therapeutic use*; D016025:Bone Transplantation; D005260:Female; D005500:Follow-Up Studies; D005898:Glass; D006801:Humans; D008159:Lumbar Vertebrae / Q000293:injuries*; D008297:Male; D008875:Middle Aged; D010147:Pain Measurement; D011446:Prospective Studies; D016103:Spinal Fractures / Q000601:surgery*; D013123:Spinal Fusion / Q000379:methods*; D014182:Transplantation, Autologous
chemical_list: D018786:Bone Substitutes; C403922:bioactive glass S53P4