title: Assessment of the levels of persistent organic pollutants and 1-hydroxypyrene in blood and urine samples from Mexican children living in an endemic malaria area in Mexico.
abstract: The aim of this study was to evaluate the exposure levels to persistent organic pollutants and 1-hydroxypyrene in children living in an endemic malaria zone in Mexico. The blood levels for 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane (DDT), 1,1-dichloro-2,2-bis(p-chlorophenyl)ethylene (DDE) and lindane ranged from 15.4 to 17,886.5 ng/g lipid, 6,624.3 to 100,119.0 ng/g lipid, and 351.1 to 6,153.8 ng/g lipid, respectively. For total polychlorinated biphenyls the blood levels ranged from 2,584.9 to 14,547.9 ng/g lipid. Regarding urinary 1-hydroxypyrene levels, the mean level was 2.9 ± 3.1 μmol/mol creatinine. In conclusion, the children in our study are exposed to levels higher than normal to mixtures of environmental contaminants.
authors.affiliation: Departamento Toxicología Ambiental, Facultad de Medicina, Universidad Autónoma de San Luis Potosí, Avenida Venustiano Carranza No. 2405, Col Lomas los Filtros, 78210, San Luis Potosí, SLP, Mexico.
authors.forename: Antonio
authors.initials: A
authors.lastname: Trejo-Acevedo
authors.forename: Norma Edith
authors.initials: NE
authors.lastname: Rivero-Pérez
authors.forename: Rogelio
authors.initials: R
authors.lastname: Flores-Ramírez
authors.forename: Sandra Teresa
authors.initials: ST
authors.lastname: Orta-García
authors.forename: José Antonio
authors.initials: JA
authors.lastname: Varela-Silva
authors.forename: Iván N
authors.initials: IN
authors.lastname: Pérez-Maldonado
mesh_terms: D000293:Adolescent; D002648:Child; D003634:DDT / Q000097:blood / Q000378:metabolism / Q000652:urine; D003633:Dichlorodiphenyl Dichloroethylene / Q000097:blood / Q000378:metabolism / Q000652:urine; D004781:Environmental Exposure / Q000032:analysis / Q000706:statistics & numerical data*; D004785:Environmental Pollutants / Q000097:blood / Q000378:metabolism* / Q000652:urine; D005260:Female; D001556:Hexachlorocyclohexane / Q000097:blood / Q000378:metabolism / Q000652:urine; D006801:Humans; D008288:Malaria / Q000453:epidemiology*; D008297:Male; D008800:Mexico; D011078:Polychlorinated Biphenyls / Q000097:blood / Q000378:metabolism / Q000652:urine; D011721:Pyrenes / Q000378:metabolism*
chemical_list: D004785:Environmental Pollutants; D011721:Pyrenes; D003633:Dichlorodiphenyl Dichloroethylene; D001556:Hexachlorocyclohexane; D003634:DDT; D011078:Polychlorinated Biphenyls; C033146:1-hydroxypyrene