title: Applications of imaging technology in radiation research.
abstract: Imaging research and advances in systems engineering have enabled the transition of medical imaging from a means for accomplishing traditional anatomic visualization (i.e., orthopedic planar film X ray) to a means for noninvasively assessing a variety of functional measures. Perfusion imaging is one of the major highlights in functional imaging. In this work, various methods for measuring perfusion using widely-available commercial imaging modalities and contrast agents, specifically X ray and MR (magnetic resonance), will be described. The first section reviews general methods used for perfusion imaging, and the second section provides modality-specific information, focusing on the contrast mechanisms used to calculate perfusion-related parameters. The goal of these descriptions is to illustrate how perfusion imaging can be applied to radiation biology research.
authors.affiliation: Clinical Informatics, Interventional, and Translational Solutions (CIITS), Philips Research North America, Briarcliff Manor, New York 10510, USA. Ming.Lin@philips.com
authors.forename: MingDe
authors.initials: M
authors.lastname: Lin
authors.forename: Edward F
authors.initials: EF
authors.lastname: Jackson
mesh_terms: D015901:Angiography, Digital Subtraction; D000818:Animals; D016477:Artifacts; D003287:Contrast Media / Q000493:pharmacokinetics; D003952:Diagnostic Imaging / Q000379:methods*; D004621:Embolization, Therapeutic / Q000379:methods; D006801:Humans; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000628:therapy; D008279:Magnetic Resonance Imaging / Q000379:methods; D008433:Mathematics; D008954:Models, Biological; D009038:Motion; D055420:Perfusion Imaging / Q000379:methods; D011853:Radiobiology / Q000379:methods*; D015641:Radiography, Interventional / Q000379:methods; D020521:Stroke / Q000000981:diagnostic imaging / Q000503:physiopathology; D036542:Tomography, Spiral Computed / Q000379:methods; D014057:Tomography, X-Ray Computed / Q000379:methods
chemical_list: D003287:Contrast Media