title: [Pathogenesis and clinical presentation of andropause].
abstract: In opposition to women, the age-related changes in reproductive hormones in men are subtle and occur gradually throughout many years of mature life. The decline in serum testosterone level may present as a constellation of signs and symptoms of hypogonadism known as "andropause". They include: loss of energy, depressed mood, decreased libido, erectile dysfunction, decreased muscle mass and strength, increased fat mass, frailty, osteopenia, and osteoporosis. Diagnosis of andropause is based on clinical symptoms and laboratory determinations of serum testosterone levels. This review summarises the present state of knowledge on the pathogenesis, clinical presentation as well as diagnosis of andropause.
authors.affiliation: Medical University of Silesia in Katowice, Poland, Department of Internal Medicine and Clinical Pharmacology. r.krysiak@interia.pl
authors.forename: Robert
authors.initials: R
authors.lastname: Krysiak
authors.forename: Bogusław
authors.initials: B
authors.lastname: Okopień
mesh_terms: D000375:Aging / Q000502:physiology*; D047649:Andropause / Q000502:physiology*; D001851:Bone Diseases, Metabolic / Q000503:physiopathology; D006801:Humans; D008297:Male; D010024:Osteoporosis / Q000503:physiopathology; D013739:Testosterone / Q000097:blood
chemical_list: D013739:Testosterone