title: [Angio-oedema and medication that interferes with the renin-angiotensin-aldosterone system--a systematic review].
abstract: Angio-oedema is a rare, but potentially life-threatening side effect to medication that interferes with the renin-angiotensin-aldosterone system. Clinically controlled trials were reviewed and the incidence assessed. We conclude, that treatment with an angiotensin receptor blocker can be tried after angiotensin-converting enzyme inhibitor (ACE-I) induced angio-oedema. The assessment should be individually based and take the severity of the previous attack and the weight of the indication into account. The risk on ACE-I might be greater in persons that have had angio-oedema for other reasons.
authors.affiliation: Det Sundhedsvidenskabelige Fakultet, Københavns Universitet, Denmark.
authors.forename: Hannah Elena
authors.initials: HE
authors.lastname: Suhrs
authors.forename: Hans
authors.initials: H
authors.lastname: Ibsen
mesh_terms: D000577:Amides / Q000009:adverse effects / Q000627:therapeutic use; D000799:Angioedema / Q000139:chemically induced*; D047228:Angiotensin II Type 1 Receptor Blockers / Q000009:adverse effects* / Q000627:therapeutic use; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000009:adverse effects* / Q000627:therapeutic use; D000959:Antihypertensive Agents / Q000009:adverse effects* / Q000627:therapeutic use; D005650:Fumarates / Q000009:adverse effects / Q000627:therapeutic use; D006801:Humans; D012084:Renin-Angiotensin System / Q000187:drug effects; D012307:Risk Factors
chemical_list: D000577:Amides; D047228:Angiotensin II Type 1 Receptor Blockers; D000806:Angiotensin-Converting Enzyme Inhibitors; D000959:Antihypertensive Agents; D005650:Fumarates; C446481:aliskiren