title: [Difficult and severe asthma in adults: definition, diagnosis and treatment].
authors.affiliation: Department of Pulmonary Medicine, Leiden University Medical Center, Leiden, Niederlande. c.taube@lumc.nl
authors.forename: C
authors.initials: C
authors.lastname: Taube
mesh_terms: D000328:Adult; D000465:Algorithms; D018927:Anti-Asthmatic Agents / Q000627:therapeutic use; D001249:Asthma / Q000175:diagnosis* / Q000453:epidemiology / Q000628:therapy*; D015897:Comorbidity; D003937:Diagnosis, Differential; D005764:Gastroesophageal Reflux / Q000453:epidemiology / Q000628:therapy; D005858:Germany / Q000453:epidemiology; D006801:Humans; D009765:Obesity / Q000453:epidemiology / Q000628:therapy; D012220:Rhinitis / Q000453:epidemiology; D012852:Sinusitis / Q000453:epidemiology; D017211:Treatment Failure
chemical_list: D018927:Anti-Asthmatic Agents