title: DNA microarray study of genes differentiating acute myocardial infarction patients from healthy persons.
abstract: OBJECTIVE
  Using oligonucleotide microarrays HG-U133A, we here studied the expression levels of genes that could differentiate between patients with myocardial infarction (MI) from healthy subjects, as well as to select among such genes those that seem crucial for manifestation of cardiovascular diseases.
  
  
  METHODS
  The microarray study was conducted using material derived from blood samples collected in 17 individuals.
  
  
  RESULTS
  Analysis of gene expression data from 17 microarrays allowed identification of 28 genes strongly differentiating the examined groups.
  
  
  CONCLUSIONS
  The differentiating genes that we tracked down indicate possible linkage with atherosclerotis and could be a prognostic marker for development of cardiovascular diseases.
authors.affiliation: Department of Epidemiology, Medical University of Silesia, Katowice, Poland. jglogowska@sum.edu.pl
authors.forename: Joanna
authors.initials: J
authors.lastname: Głogowska-Ligus
authors.forename: Józefa
authors.initials: J
authors.lastname: Dąbek
mesh_terms: D000208:Acute Disease; D015415:Biomarkers; D016022:Case-Control Studies; D016000:Cluster Analysis; D020869:Gene Expression Profiling; D005796:Genes; D006801:Humans; D025202:Molecular Diagnostic Techniques; D009203:Myocardial Infarction / Q000175:diagnosis / Q000235:genetics* / Q000378:metabolism; D020411:Oligonucleotide Array Sequence Analysis
chemical_list: D015415:Biomarkers