title: Percutaneous closure of an atrial septal defect in an infant with Shone's syndrome.
abstract: Rarely is closure of the atrial septal defect indicated in infants. Yet, an atrial septal defect in the presence of congenital mitral stenosis may cause significant congestive heart failure in infancy. We present the case of an infant with Shone's syndrome, left ventricular hypoplasia, and a large ostium secundum atrial septal defect who developed pulmonary overcirculation following repair of coarctation of the aorta. The infant underwent cardiac catheterization, hemodynamic assessment, and successful percutaneous closure of the atrial septal defect. The patient improved dramatically following the intervention. Follow-up echocardiograms have demonstrated growth of mitral valve annulus diameter and left ventricular dimensions. Atrial septal defect closure in this small infant was associated with immediate improved clinical status, and improved growth of the left heart structures.
authors.affiliation: Lillie Frank Abercrombie Section of Cardiology, Department of Pediatrics, Texas Children's Hospital, Houston, Texas 77030, USA. petit@bcm.edu
authors.forename: Christopher J
authors.initials: CJ
authors.lastname: Petit
authors.forename: Henri
authors.initials: H
authors.lastname: Justino
authors.forename: Charles D
authors.initials: CD
authors.lastname: Fraser
mesh_terms: D000015:Abnormalities, Multiple; D006328:Cardiac Catheterization / Q000295:instrumentation; D006344:Heart Septal Defects, Atrial / Q000150:complications / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000628:therapy*; D006439:Hemodynamics; D006801:Humans; D007231:Infant, Newborn; D008946:Mitral Valve Stenosis / Q000151:congenital* / Q000000981:diagnostic imaging / Q000503:physiopathology; D011474:Prosthesis Design; D055989:Septal Occluder Device; D013577:Syndrome; D016896:Treatment Outcome; D014463:Ultrasonography