title: Segmental bowel resection for colorectal endometriosis: is there a correlation between histological pattern and clinical outcomes?
abstract: BACKGROUND
  Laparoscopic segmental resection as a treatment for intestinal endometriosis can be supported by favorable clinical outcomes, but carries a high risk of major complications. The purpose of this study is to evaluate histopathological patterns of colorectal endometriosis and investigate potential relationships between histological findings and clinical data.
  
  
  METHODS
  We consecutively included 47 patients treated with laparoscopic segmental resection because of symptomatic colorectal endometriosis. All patients underwent follow-up for a median of 18 months (range: 6-35). We examined the histological patterns of colorectal endometriosis and evaluated the relationships between histological findings (satellite lesions, positive margins and vertical infiltration) and clinical outcomes (incidence of recurrence, quality of life and symptom improvement). Moreover, we observed if satellite lesions could influence preoperative scores of the short form-36 health survey (SF-36) questionnaire and visual analogue score (VAS) for pain symptoms.
  
  
  RESULTS
  There were no statistically significant differences in terms of anatomical and pain recurrences, pain symptoms and quality of life improvement among patients with or without positive margins, satellite lesions and different degrees of vertical infiltration (P > 0.05). Furthermore, women with or without satellite lesions were no different in terms of preoperative VAS of pain symptoms and SF-36 scores (P > 0.05).
  
  
  CONCLUSIONS
  The presence of satellite lesions or positive resection margins does not seem to influence clinical outcomes of segmental colorectal resection. Similarly, satellite lesions do not appear to have a major role in determining preoperative clinical presentation. These results may be useful to reconsider the surgical strategy for bowel endometriosis.
authors.affiliation: The Minimally Invasive Gynaecological Surgery Unit, Gynaecology Department, S.Orsola-Malpighi Hospital, University of Bologna, Via Massarenti 13, Bologna 40138, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Mabrouk
authors.forename: E
authors.initials: E
authors.lastname: Spagnolo
authors.forename: D
authors.initials: D
authors.lastname: Raimondo
authors.forename: A
authors.initials: A
authors.lastname: D'Errico
authors.forename: G
authors.initials: G
authors.lastname: Caprara
authors.forename: D
authors.initials: D
authors.lastname: Malvi
authors.forename: F
authors.initials: F
authors.lastname: Catena
authors.forename: G
authors.initials: G
authors.lastname: Ferrini
authors.forename: R
authors.initials: R
authors.lastname: Paradisi
authors.forename: R
authors.initials: R
authors.lastname: Seracchioli
mesh_terms: D003108:Colonic Diseases / Q000473:pathology / Q000601:surgery*; D004715:Endometriosis / Q000473:pathology / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D041981:Gastrointestinal Tract / Q000601:surgery*; D006801:Humans; D011183:Postoperative Complications; D011788:Quality of Life; D012002:Rectal Diseases / Q000473:pathology / Q000601:surgery*; D012008:Recurrence; D016896:Treatment Outcome