title: Image-guided needle biopsy for diagnosis and molecular biology in lymphomas.
abstract: Core needle biopsy is increasingly replacing excisional lymph node biopsy in the diagnosis and subclassification of malignant lymphomas, with obvious advantages in terms of morbidity and costs. This technique has radically altered the diagnostic strategy of enlarged lymph nodes at our institution, avoiding unnecessary nodal excisions. It represents a viable alternative as long as the number and size of cores for morphologic and molecular studies are not compromised. This quick and safe technique can be applied to the initial diagnostic evaluation of malignant lymphomas as well as the reassessment of previously diagnosed malignant lymphomas at time of progression or recurrence.
authors.affiliation: Service de Radiologie, Hôpital Saint-Louis APHP, Université Paris Diderot, France. eric.de-kerviler@sls.aphp.fr
authors.forename: E
authors.initials: E
authors.lastname: de Kerviler
authors.forename: C
authors.initials: C
authors.lastname: Benet
authors.forename: J
authors.initials: J
authors.lastname: Brière
authors.forename: C
authors.initials: C
authors.lastname: de Bazelaire
mesh_terms: D014408:Biomarkers, Tumor / Q000235:genetics / Q000378:metabolism; D001707:Biopsy, Needle / Q000379:methods*; D018450:Disease Progression; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D007150:Immunohistochemistry; D017404:In Situ Hybridization, Fluorescence; D008198:Lymph Nodes / Q000000981:diagnostic imaging / Q000473:pathology*; D008223:Lymphoma / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000235:genetics / Q000473:pathology; D012008:Recurrence; D013048:Specimen Handling; D014054:Tomography; D014463:Ultrasonography
chemical_list: D014408:Biomarkers, Tumor