title: The use of tranexamic acid for trauma patients?
abstract: OBJECTIVE
  Does giving tranexamic acid to trauma patients who are actively bleeding or at risk for significant hemorrhage have an impact on mortality?
  
  
  METHODS
  CRASH-2 Trial Collaborators. Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial. Lancet 2010;376:23-32.
  
  
  OBJECTIVE
  The study collaborators sought to evaluate the effect of tranexamic acid on mortality in trauma patients who were actively bleeding or at risk for significant hemorrhage. Secondary outcomes included the incidence of vascular occlusive events and the number of blood transfusions required.
authors.affiliation: Department of Emergency Medicine, University of Alberta, Edmonton, USA. bryanjweber@ualberta.ca
authors.forename: Bryan J
authors.initials: BJ
authors.lastname: Weber
authors.forename: Colleen B
authors.initials: CB
authors.lastname: Kjelland