title: Liquid chromatography-flame ionisation detection using a nebuliser/spray chamber interface. Part 1. Design and testing.
abstract: A nebuliser and spray chamber have been used to link a flow injection analyser to a flame ionisation detector, with the potential for the combination to be used as a universal detector for liquid chromatography. The hydrogen and air flows were adjusted to achieve a stable system. The detector responded to both volatile and involatile analytes and to compounds with and without chromophores, including alkanes, alkanols, aromatic amides and acids, phenols, amino-acids and carbohydrates and gave a linear response for many analytes. However, for involatile polar analytes it was necessary to add traces of acid or salt to the carrier stream to obtain a linear response.
authors.affiliation: Department of Chemistry, Loughborough University, Loughborough, Leicestershire, LE11 3TU, UK.
authors.forename: Erepamowei
authors.initials: E
authors.lastname: Young
authors.forename: Roger M
authors.initials: RM
authors.lastname: Smith
authors.forename: Barry L
authors.initials: BL
authors.lastname: Sharp
authors.forename: Joanne R
authors.initials: JR
authors.lastname: Bone
mesh_terms: D002853:Chromatography, Liquid / Q000295:instrumentation* / Q000379:methods*; D004867:Equipment Design; D005410:Flame Ionization / Q000295:instrumentation*; D017022:Flow Injection Analysis / Q000295:instrumentation*; D006859:Hydrogen / Q000737:chemistry; D006863:Hydrogen-Ion Concentration; D016014:Linear Models; D009330:Nebulizers and Vaporizers; D009930:Organic Chemicals / Q000032:analysis / Q000737:chemistry; D012492:Salts / Q000737:chemistry; D014867:Water / Q000737:chemistry
chemical_list: D009930:Organic Chemicals; D012492:Salts; D014867:Water; D006859:Hydrogen