title: Unusual presentation of metastatic Ewing sarcoma to the ovary in a 13 year-old: a case report and review.
abstract: Ewing sarcoma (ES) is the second most common bone malignancy in children and adolescents. Together with primitive neuroectodermal tumors (PNET), ES comprises the PNET/ES family. Metastasis is present in about 25% of patients at diagnosis and is most commonly found in the lung and bones. Primary PNET/ES of the ovary has been reported in many adult cases; however, secondary occurrences are rare. Here we present the clinical course of a 13-year-old patient with metastatic ES to the ovary without involvement of any other sites. To our knowledge, this is the second reported pediatric case of metastatic ES to the ovary.
authors.affiliation: Department of Pathology, Emory University School of Medicine, Atlanta, Georgia 30322, USA.
authors.forename: Harold Cliff
authors.initials: HC
authors.lastname: Sullivan
authors.forename: Sarah Catherine
authors.initials: SC
authors.lastname: Shulman
authors.forename: Thomas
authors.initials: T
authors.lastname: Olson
authors.forename: Richard
authors.initials: R
authors.lastname: Ricketts
authors.forename: Shervin
authors.initials: S
authors.lastname: Oskouei
authors.forename: Bahig M
authors.initials: BM
authors.lastname: Shehata
mesh_terms: D000293:Adolescent; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001859:Bone Neoplasms / Q000473:pathology* / Q000628:therapy; D003131:Combined Modality Therapy; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D019637:Orthopedic Procedures; D010051:Ovarian Neoplasms / Q000556:secondary* / Q000628:therapy; D010052:Ovariectomy; D058994:Salpingectomy; D012512:Sarcoma, Ewing / Q000556:secondary* / Q000628:therapy