title: [Role of FDG-PET scanning in stage IIIAN2 non-small cell lung cancer].
abstract: Patients with clinical stage IIIAN2 non-small cell lung cancer (NSCLC) are a heterogeneous subgroup in term of prognosis and therapeutic management. The optimal management of this patient group is a major focus for thoracic oncology research and the concept of multimodality treatment has recently been introduced. This approach combines induction chemotherapy or radiochemotherapy followed by surgery in the case of mediastinal lymph node down-staging. positron emission tomography computed tomography with [18F]-fluorodesoxyglucose (FDG-PET) is a molecular and metabolic imaging modality which combines the metabolic data of PET with morphological data from CT. FDG-PET has become a standard in lung cancer management since the different indications listed in the standards, options and recommendations (SOR) of the FNCLCC. However, the potential specific importance of FDG-PET in IIIAN2 patients needs to be addressed further. In this setting, the authors' objective is to review the potential role of metabolic imaging in stage IIIAN2 NSCLC, taking into account new multimodality treatments. In stage IIIAN2, FDG-PET has performed better than morphoradiological imaging for baseline and postinduction lymph node staging, the identification of distant metastasis, and determining prognosis, as well as assessing the response to treatment.
authors.affiliation: Service central de biophysique et de médecine nucléaire, CHU La Timone, 264 rue Saint-Pierre, Marseille cedex 5, France. cecile.colavolpe@ap-hm.fr
authors.forename: C
authors.initials: C
authors.lastname: Colavolpe
authors.forename: G
authors.initials: G
authors.lastname: Bonardel
authors.forename: E
authors.initials: E
authors.lastname: Guedj
authors.forename: S
authors.initials: S
authors.lastname: Cammilleri
authors.forename: O
authors.initials: O
authors.lastname: Mundler
authors.forename: F
authors.initials: F
authors.lastname: Barlesi
mesh_terms: D002289:Carcinoma, Non-Small-Cell Lung / Q000000981:diagnostic imaging* / Q000473:pathology / Q000628:therapy; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000628:therapy; D008198:Lymph Nodes / Q000000981:diagnostic imaging / Q000473:pathology; D009367:Neoplasm Staging / Q000379:methods; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18