title: The role of mineralocorticoid receptor antagonists in patients with American College of Cardiology/American Heart Association stage B heart failure.
abstract: This article focuses on the potential role of mineralocorticoid receptor antagonists (MRAs) in patients with stage B heart failure (HF) due to hypertension, diabetes mellitus, and/or visceral obesity with the metabolic syndrome. It briefly discusses the role of MRAs in patients with left ventricular dilatation due to nonischemic or ischemic cardiomyopathy and in those with a prior myocardial infarction but without left ventricular dilatation or evidence of HF.
authors.affiliation: Cardiovascular Center, University Hospital, University of Michigan School of Medicine, 1500 East Medical Center Drive, Ann Arbor, MI 48109-5853, USA.
authors.forename: Bertram
authors.initials: B
authors.lastname: Pitt
mesh_terms: D000311:Adrenal Glands / Q000378:metabolism; D000450:Aldosterone / Q000097:blood / Q000378:metabolism; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000494:pharmacology / Q000627:therapeutic use; D000818:Animals; D004656:Enalapril / Q000494:pharmacology / Q000627:therapeutic use; D004730:Endothelium, Vascular / Q000187:drug effects; D005919:Glomerular Filtration Rate; D006333:Heart Failure / Q000188:drug therapy* / Q000503:physiopathology / Q000517:prevention & control; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D017379:Hypertrophy, Left Ventricular; D000451:Mineralocorticoid Receptor Antagonists; D011188:Potassium / Q000097:blood; D013148:Spironolactone / Q000494:pharmacology / Q000627:therapeutic use
chemical_list: D000806:Angiotensin-Converting Enzyme Inhibitors; D000451:Mineralocorticoid Receptor Antagonists; D013148:Spironolactone; D000450:Aldosterone; D004656:Enalapril; D011188:Potassium; D006854:Hydrocortisone