title: Renal BOLD-MRI and assessment for renal hypoxia.
abstract: Renal tissue hypoxia may play a major role in the progression of chronic renal disease. Michaely et al. used blood oxygen level-dependent magnetic resonance imaging to test this hypothesis. They found no relationship between renal oxygenation and stage of chronic kidney disease (CKD). However, renal tissue oxygenation may be related not only to the severity of renal disease but also to its underlying etiology. This added complexity confounds interpretation of data obtained from subjects with CKD due to multiple etiologies.
authors.forename: Joel
authors.initials: J
authors.lastname: Neugarten
mesh_terms: D000818:Animals; D004921:Erythropoietin / Q000096:biosynthesis*; D005260:Female; D006801:Humans; D007672:Kidney Cortex / Q000378:metabolism*; D007677:Kidney Function Tests / Q000379:methods*; D007679:Kidney Medulla / Q000378:metabolism*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D010100:Oxygen / Q000097:blood* / Q000378:metabolism*; D051436:Renal Insufficiency, Chronic / Q000097:blood* / Q000503:physiopathology*
chemical_list: D004921:Erythropoietin; D010100:Oxygen