title: Facile method for synthesis of hollow porous magnetic microspheres with controllable structure.
abstract: Hollow porous magnetic microspheres with strong magnetization and controllable structure were prepared via a facile electrostatic self-assembly of the positively charged Fe(3)O(4) nanoparticles onto the surface of the negatively charged poly(N,N'-methylenebisacrylamide-co-methacrylic acid) (P(MBAAm-co-MAA)) microspheres with subsequent removal of the polymer core through calcination at high temperature. The shell thickness was facilely tuned through the ratio between Fe(3)O(4) and polymer, and the void space was conveniently changed through the size of polymer microspheres. The hollow magnetic microspheres possessed high saturation magnetization value (51.38 emu/g) and porous structure with high specific surface area (108.04 m(2)/g). Based on these properties, the drug loading and release behaviors were investigated, which indicated that the hollow magnetic microspheres exhibited a controlled release process.
authors.affiliation: Key Laboratory of Functional Polymer Materials, The Ministry of Education, Institute of Polymer Chemistry, Nankai University, Tianjin 300071, PR China.
authors.forename: Bin
authors.initials: B
authors.lastname: Liu
authors.forename: Wei
authors.initials: W
authors.lastname: Zhang
authors.forename: Qingyun
authors.initials: Q
authors.lastname: Zhang
authors.forename: Han
authors.initials: H
authors.lastname: Zhang
authors.forename: Jing
authors.initials: J
authors.lastname: Yu
authors.forename: Xinlin
authors.initials: X
authors.lastname: Yang