title: A glycosyltransferase inhibitor from a molecular fragment library simultaneously interferes with metal ion and substrate binding.
authors.affiliation: Carlsberg Laboratory, Gamle Carlsberg Vej 10, 1799 Copenhagen V, Denmark.
authors.forename: Rene
authors.initials: R
authors.lastname: Jørgensen
authors.forename: Lena Lisbeth
authors.initials: LL
authors.lastname: Grimm
authors.forename: Nora
authors.initials: N
authors.lastname: Sindhuwinata
authors.forename: Thomas
authors.initials: T
authors.lastname: Peters
authors.forename: Monica M
authors.initials: MM
authors.lastname: Palcic
mesh_terms: D001789:Blood Group Antigens; D020134:Catalytic Domain; D002413:Cations, Divalent / Q000737:chemistry; D004791:Enzyme Inhibitors / Q000737:chemistry* / Q000494:pharmacology; D016695:Glycosyltransferases / Q000037:antagonists & inhibitors*; D006801:Humans; D006860:Hydrogen Bonding; D008345:Manganese / Q000737:chemistry*; D008958:Models, Molecular; D011485:Protein Binding / Q000187:drug effects; D054730:Protein Interaction Domains and Motifs; D054852:Small Molecule Libraries / Q000737:chemistry*; D013379:Substrate Specificity / Q000187:drug effects
chemical_list: D001789:Blood Group Antigens; D002413:Cations, Divalent; D004791:Enzyme Inhibitors; D054852:Small Molecule Libraries; D008345:Manganese; D016695:Glycosyltransferases