title: Optical coherence tomography for whole eye segment imaging.
abstract: We proposed a dual focus dual channel spectral domain optical coherence tomography (SD-OCT) for simultaneous imaging of the whole eye segments from cornea to the retina. By using dual channels the system solved the problem of limited imaging depth of SD-OCT. By using dual focus the system solved the problem of simultaneous light focusing on the anterior segment of the eye and the retina. Dual focusing was achieved by adjusting the collimating lenses so the divergence of the two probing beams was tuned to make them focused at different depth in the eye. We further achieved full range complex (FRC) SD-OCT in one channel to increase the depth range for anterior segment imaging. The system was successfully tested by imaging a human eye in vivo.
authors.affiliation: School of Biomedical Engineering, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai 200240, China.
authors.forename: Cuixia
authors.initials: C
authors.lastname: Dai
authors.forename: Chuanqing
authors.initials: C
authors.lastname: Zhou
authors.forename: Shanhui
authors.initials: S
authors.lastname: Fan
authors.forename: Zhe
authors.initials: Z
authors.lastname: Chen
authors.forename: Xinyu
authors.initials: X
authors.lastname: Chai
authors.forename: Qiushi
authors.initials: Q
authors.lastname: Ren
authors.forename: Shuliang
authors.initials: S
authors.lastname: Jiao
mesh_terms: D004867:Equipment Design; D019544:Equipment Failure Analysis; D005123:Eye / Q000033:anatomy & histology*; D006801:Humans; D007089:Image Enhancement / Q000295:instrumentation*; D019721:Ophthalmoscopes; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D041623:Tomography, Optical Coherence / Q000295:instrumentation*