title: Surface modification of PBT nonwoven fabrics used for blood filtration and their blood compatibility study.
abstract: It is necessary to remove residual leukocytes to prevent the blood transfusion-related adverse reactions. This paper describes a facile approach for the surface modification of commercial PBT nonwoven fabrics (PBTNF), used for blood filtration, followed by immobilizing polyvinylpyrrolidone (PVP). The whole blood filtration results revealed that the five types of PBTNF-PVPs' leucocytes retention rates and erythrocyte recovery rates increased to 96% and 92% compared with the untreated PBTNF. The blood compatibilities results indicated that PVP modified PBTNFs have good blood compatibility, suggesting that PVP-modified PBTNF is a very promising blood filter for selective removal of leukocytes.
authors.affiliation: Institute of Blood Transfusion, Chinese Academy of Medical Sciences and Peking Union Medical College, Chengdu, China.
authors.forename: Ye
authors.initials: Y
authors.lastname: Cao
authors.forename: Jiaxin
authors.initials: J
authors.lastname: Liu
authors.forename: Rui
authors.initials: R
authors.lastname: Zhong
authors.forename: Qing
authors.initials: Q
authors.lastname: Yu
authors.forename: Hong
authors.initials: H
authors.lastname: Wang
mesh_terms: D001789:Blood Group Antigens / Q000276:immunology; D004912:Erythrocytes / Q000473:pathology; D006648:Histocompatibility; D006801:Humans; D047589:Leukocyte Reduction Procedures / Q000295:instrumentation* / Q000379:methods; D007962:Leukocytes / Q000276:immunology / Q000473:pathology*; D056951:Photoelectron Spectroscopy; D011205:Povidone; D013499:Surface Properties; D065227:Transfusion Reaction
chemical_list: D001789:Blood Group Antigens; D011205:Povidone