title: Spindle cell epulis in an 8-month-old child: a histologic variant of congenital granular cell epulis?
abstract: A case of an epulis in an 8-month-old boy is reported. The tumor was localized on the mandibular alveolar ridge and, according to the parents, was a recurrence of a congenital tumor excised when the boy was 2 months old. Microscopically, it was composed of many spindled or ovoid cells with vesicular nuclei and non-granular eosinophilic cytoplasm, and covered by acanthotic parakeratinized squamous epithelium with broad rete pegs. Immunohistochemically, the spindled and ovoid cells were intensely positive for vimentin and neuron-specific enolase, and negative for S-100 protein. The final diagnosis was spindle cell epulis. The possible correlation of this lesion with congenital granular cell epulis is discussed.
authors.affiliation: Department of Oral Pathology, Dental School, University of Athens, 2 Thivon street, 11527 Athens, Greece.
authors.forename: Andreas-Christoforos
authors.initials: AC
authors.lastname: Prigkos
authors.forename: Michail D
authors.initials: MD
authors.lastname: Nikolakis
authors.forename: Vasileios F
authors.initials: VF
authors.lastname: Kyriakopoulos
authors.forename: Konstantinos I
authors.initials: KI
authors.lastname: Tosios
mesh_terms: D005887:Gingival Neoplasms / Q000151:congenital* / Q000473:pathology* / Q000601:surgery; D016586:Granular Cell Tumor / Q000151:congenital* / Q000473:pathology / Q000601:surgery; D006801:Humans; D007150:Immunohistochemistry; D007223:Infant; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000378:metabolism / Q000473:pathology / Q000601:surgery