title: History of allergy is a predictor of adverse events in unstable angina treated with coronary angioplasty.
abstract: BACKGROUND
  The aim was to investigate prognostic relevance of history of allergy in subjects with unstable angina treated with coronary angioplasty.
  
  
  METHODS
  Fifty-seven consecutive patients with unstable angina who underwent coronary angioplasty were enrolled in the study and were divided into two groups: those with a history of allergy (Group A, N = 15); and controls (Group C, N =42). Major adverse cardiac events were recorded over a six-month follow-up period. Patients with primary or unsuccessful angioplasty and patients treated with drug eluting stent were excluded from the study.
  
  
  RESULTS
  Group A patients (history of allergy) showed a 46.67% incidence of major adverse cardiac events at six-month follow-up (vs. 9.52% Group C, p < 0.01): results remained significant even in a multiple Cox regression analysis (hazard ratio 7.17, 95% CI 1.71-29.98, p < 0.01).
  
  
  CONCLUSIONS
  History of allergy is an independent predictor of major adverse cardiac events after coronary angioplasty in a six-month follow-up period in unstable angina.
authors.affiliation: Cardiology Department, University of Foggia, Foggia, Italy. Electronic address: nd.brunetti@unifg.it.
authors.forename: N D
authors.initials: ND
authors.lastname: Brunetti
authors.affiliation: Cardiology Department, University of Foggia, Foggia, Italy.
authors.forename: L
authors.initials: L
authors.lastname: De Gennaro
authors.affiliation: Cardiology Department, University of Foggia, Foggia, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Cuculo
authors.affiliation: Cardiology Department, University of Foggia, Foggia, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Gaglione
authors.affiliation: Cardiology Department, University of Foggia, Foggia, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Di Biase
mesh_terms: D000368:Aged; D000789:Angina, Unstable / Q000601:surgery*; D015906:Angioplasty, Balloon, Coronary / Q000009:adverse effects*; D003645:Death, Sudden; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006967:Hypersensitivity / Q000453:epidemiology*; D015994:Incidence; D008297:Male; D008487:Medical History Taking; D008875:Middle Aged; D009203:Myocardial Infarction / Q000453:epidemiology; D011183:Postoperative Complications / Q000453:epidemiology*; D011237:Predictive Value of Tests; D011379:Prognosis; D012008:Recurrence; D016896:Treatment Outcome