title: Practice referral patterns and outcomes in patients with primary retroperitoneal sarcoma in British Columbia.
abstract: BACKGROUND
  We examined practice referral patterns for primary retroperitoneal sarcoma (PRS) in British Columbia (BC) and associations between the timing of referral to tertiary care and patient outcomes.
  
  
  METHODS
  Using ICD-10 coding, the Cancer Agency Information System was used to identify patients with PRS from 2000 to 2009 who had been referred to tertiary care and had undergone a surgical resection.
  
  
  RESULTS
  Eighty-two patients were included. Those referred before surgery were significantly more likely to receive a complete resection (P = .0002) and adjuvant radiation (P = .0000) compared with patients referred after surgery. Referral before surgery was associated with a significantly increased overall (P = .0619) and recurrence-free (P = .0400) survival; however, in the multivariate model this was not significant.
  
  
  CONCLUSIONS
  Referral before surgery is associated with higher rates of complete resection and the use of adjuvant radiation; furthermore, it is associated with prolonged survival in the univariate but not in the multivariate model.
authors.affiliation: BC Cancer Agency, 600 West 10th Avenue, Vancouver, British Columbia V5Z 4E6, Canada.
authors.forename: Shaila
authors.initials: S
authors.lastname: Merchant
authors.affiliation: BC Cancer Agency, 600 West 10th Avenue, Vancouver, British Columbia V5Z 4E6, Canada. Electronic address: rcheifetz@bccancer.bc.ca.
authors.forename: Rona
authors.initials: R
authors.lastname: Cheifetz
authors.affiliation: BC Cancer Agency, 600 West 10th Avenue, Vancouver, British Columbia V5Z 4E6, Canada.
authors.forename: Margaret
authors.initials: M
authors.lastname: Knowling
authors.affiliation: BC Cancer Agency, 600 West 10th Avenue, Vancouver, British Columbia V5Z 4E6, Canada.
authors.forename: Fareeza
authors.initials: F
authors.lastname: Khurshed
authors.affiliation: BC Cancer Agency, 600 West 10th Avenue, Vancouver, British Columbia V5Z 4E6, Canada.
authors.forename: Colleen
authors.initials: C
authors.lastname: McGahan
mesh_terms: D000368:Aged; D001955:British Columbia; D005260:Female; D006801:Humans; D008297:Male; D015999:Multivariate Analysis; D010818:Practice Patterns, Physicians'; D012017:Referral and Consultation / Q000706:statistics & numerical data*; D012186:Retroperitoneal Neoplasms / Q000401:mortality / Q000601:surgery*; D012509:Sarcoma / Q000401:mortality / Q000601:surgery*; D015996:Survival Rate; D016896:Treatment Outcome