title: Fine structure and related properties of the assembleable carbon nanotubes based electrode for new family of biosensors with chooseable selectivity.
abstract: Surfaces of constituent parts of biosensors based on single wall carbon nanotube layer were investigated and compare for properly functioning and faulty biosensors. Though the original technology is acceptable for changing of the selectivity, only glucose sensitive biosensors are investigated. Based on the results of the study, a correlation between the features of the nanoscale structures and parameters of amperiometric biosensors for assemblage of which an innovative approach is described. Original template of the electrodes has been prepared on a base of single wall carbon nanotube layer deposited on the supporting polycarbonate membrane. Original immobilisation of enzymes within special membrane allows functional modification of biosensors being accomplished by simple replacement of the enzymatic membrane. The original technology leads to a novel family of biosensors acceptable for detection of wide range of carbohydrates. The morphology and the local electric properties of the constituent parts of the biosensors are characterized by scanning probe microscopy. The sensitivity, selectivity and stability are described for typical types of the biosensors.
authors.affiliation: Institute of Biochemistry, Department of Bioanalysis, Mokslininku 12, LT08662 Vilnius, Lithuania.
authors.forename: Julija
authors.initials: J
authors.lastname: Razumiene
authors.forename: Vidute
authors.initials: V
authors.lastname: Gureviciene
authors.forename: Edita
authors.initials: E
authors.lastname: Voitechovic
authors.forename: Jurgis
authors.initials: J
authors.lastname: Barkauskas
authors.forename: Virginijus
authors.initials: V
authors.lastname: Bukauskas
authors.forename: Arūnas
authors.initials: A
authors.lastname: Setkus
mesh_terms: D015374:Biosensing Techniques; D002241:Carbohydrates / Q000737:chemistry; D004566:Electrodes; D004800:Enzymes, Immobilized / Q000737:chemistry; D005947:Glucose / Q000737:chemistry; D020527:Microscopy, Scanning Probe / Q000379:methods; D037742:Nanotubes, Carbon / Q000737:chemistry*; D011076:Polycarboxylate Cement / Q000737:chemistry; D012680:Sensitivity and Specificity
chemical_list: D002241:Carbohydrates; D004800:Enzymes, Immobilized; D037742:Nanotubes, Carbon; D011076:Polycarboxylate Cement; C005506:polycarbonate; D005947:Glucose