title: Bilateral dislocation of temporomandibular joint induced by haloperidol following suicide attempt: a case report.
abstract: Drug induced dystonic reactions are among common presentations of patients in emergency departments, and typically occur with antidopaminergic agents as their extra-pyramidal side effects. Dystonic reactions usually occur within the first few hours or days after commencing a drug or dose increase. Unlike other extra-pyramidal side effects, a patient may experience acute dystonic reactions (ADRs) with the administration of just a single dose. Oromandibular dystonia is a subtype of dystonia which can present with perioral manifestations. In extreme cases, it can lead to temporomandibular dislocation. Haloperidol, as a high potent typical antipsychotic drug, can induce dystonia with blocking D2 dopamine receptors. The present paper reports a case of bilateral dislocation of temporomandibular joint following ingestion of haloperidol in a suicidal attempt in a 17 years old girl.
authors.affiliation: Department of Medical Sciences and Toxicology, School of Medicine, Tehran University of Medical Sciences, Iran.
authors.forename: Zakaria
authors.initials: Z
authors.lastname: Zakariaei
authors.forename: Shervin
authors.initials: S
authors.lastname: Taslimi
authors.forename: Mohammad Amin
authors.initials: MA
authors.lastname: Tabatabaiefar
authors.forename: Mosa
authors.initials: M
authors.lastname: Arghand Dargahi
mesh_terms: D000293:Adolescent; D018492:Dopamine Antagonists / Q000009:adverse effects*; D004421:Dystonia / Q000139:chemically induced* / Q000503:physiopathology / Q000628:therapy; D005260:Female; D006220:Haloperidol / Q000009:adverse effects*; D006801:Humans; D004204:Joint Dislocations / Q000139:chemically induced* / Q000503:physiopathology / Q000628:therapy; D013406:Suicide, Attempted; D013704:Temporomandibular Joint / Q000187:drug effects* / Q000503:physiopathology
chemical_list: D018492:Dopamine Antagonists; D006220:Haloperidol