title: Cancer with unknown primary: finding a needle in a hay stack.
abstract: Detection and resection of small neuroendocrine tumours (NET) is like finding a needle in a hay stack. Use of specific tracers such as (68)Ga-DOTATOC in a PET/CT study has been proven to have a high sensitivity and specificity to cells expressing somatostatin-SSR receptors. The use of (99m)Tc-Octreotide to detect neuroendocrine tumours during surgery is an effective adjunct for therapy. We here present a clinical case of patient with NET where these modalities help in both diagnostic and therapeutic surgery.
authors.affiliation: Department of Nuclear Medicine, University Hospital Heidelberg, Heidelberg, Germany. f.giesel@dkfz.de
authors.forename: F L
authors.initials: FL
authors.lastname: Giesel
authors.forename: A
authors.initials: A
authors.lastname: Mehndiratta
authors.forename: M P
authors.initials: MP
authors.lastname: Mafomane
authors.forename: C M
authors.initials: CM
authors.lastname: Zechmann
authors.forename: F
authors.initials: F
authors.lastname: Bergmann
authors.forename: P
authors.initials: P
authors.lastname: Schemmer
authors.forename: U
authors.initials: U
authors.lastname: Haberkorn
authors.forename: C
authors.initials: C
authors.lastname: Kratochwil
mesh_terms: D006801:Humans; D008875:Middle Aged; D064847:Multimodal Imaging; D009382:Neoplasms, Unknown Primary / Q000000981:diagnostic imaging* / Q000473:pathology; D018358:Neuroendocrine Tumors / Q000000981:diagnostic imaging* / Q000473:pathology / Q000556:secondary*; D015282:Octreotide / Q000031:analogs & derivatives; D009942:Organometallic Compounds; D049268:Positron-Emission Tomography; D011379:Prognosis; D019275:Radiopharmaceuticals; D013667:Technetium; D014057:Tomography, X-Ray Computed
chemical_list: C499142:Ga(III)-DOTATOC; D009942:Organometallic Compounds; D019275:Radiopharmaceuticals; D013667:Technetium; D015282:Octreotide