title: Peptidoglycan assembly machines: the biochemical evidence.
abstract: To make progress in understanding peptidoglycan metabolism, we will reconstitute in vitro the assembly process and the molecular machineries that carry out this formidable task. We review here the reports of isolation of complexes comprising penicillin-binding proteins (PBPs), the enzymes that synthesize the peptidoglycan from its lipid-linked precursor.
authors.affiliation: Commissariat à l'Energie Nucléaire, Institut de Biologie Structurale, Grenoble, France.
authors.forename: André
authors.initials: A
authors.lastname: Zapun
authors.forename: Marjolaine
authors.initials: M
authors.lastname: Noirclerc-Savoye
authors.forename: Nordine
authors.initials: N
authors.lastname: Helassa
authors.forename: Thierry
authors.initials: T
authors.lastname: Vernet
mesh_terms: D002352:Carrier Proteins / Q000235:genetics / Q000378:metabolism; D002473:Cell Wall / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D002846:Chromatography, Affinity; D004926:Escherichia coli / Q000235:genetics / Q000378:metabolism*; D016695:Glycosyltransferases / Q000235:genetics / Q000378:metabolism; D047468:Immunoprecipitation; D002267:Muramoylpentapeptide Carboxypeptidase / Q000235:genetics / Q000378:metabolism; D046915:Penicillin-Binding Proteins / Q000235:genetics / Q000378:metabolism; D010457:Peptidoglycan / Q000096:biosynthesis*; D013194:Staining and Labeling
chemical_list: D002352:Carrier Proteins; D046915:Penicillin-Binding Proteins; D010457:Peptidoglycan; D016695:Glycosyltransferases; D002267:Muramoylpentapeptide Carboxypeptidase