title: Intravenous bisphosphonate therapy for children who have a traumatic fracture neck of femur and osteonecrosis: a case report.
abstract: BACKGROUND
  Prognosis of traumatic osteonecrosis of femoral head in children is poor for either conservative treatment or surgical intervention. Intravenous bisphosphonate is an expecting medication to reduce femoral head resorption and to prevent femoral head collapse after traumatic osteonecrosis. This mechanism will reduce development of osteoarthritis and disability in the future.
  
  
  OBJECTIVE
  Report the result of the effectiveness of intravenous bisphosphonate in treatment of a child with traumatic fracture neck of femur and developed osteonecrosis.
  
  
  METHODS
  A case report was done between May 2008 and June 2010. The patient developed traumatic osteonecrosis of the right femoral head after multiple screws fixation in treatment of femoral neck fracture. Intravenous bisphosphonate was given every other month for two years.
  
  
  RESULTS
  A 13-year-old girl who had a motorcycle accident developed avascular necrosis after multiple screws fixation of femoral neck fracture. After an intravenous bisphosphonate was given every other month for two years, the last follow-up showed good prognosis.
authors.affiliation: Department of Orthopedics, Hatyai Hospital Center Hat Yai, Songkhla, Thailand. orthohatyai@hotmail.com
authors.forename: Satapong
authors.initials: S
authors.lastname: Pisuitthanakan
authors.forename: Teerapon
authors.initials: T
authors.lastname: Premprabha
mesh_terms: D000063:Accidents, Traffic; D000293:Adolescent; D016723:Bone Remodeling; D004164:Diphosphonates / Q000008:administration & dosage; D005260:Female; D005265:Femoral Neck Fractures / Q000601:surgery*; D005271:Femur Head Necrosis / Q000188:drug therapy* / Q000503:physiopathology; D005593:Fracture Fixation, Internal; D006801:Humans; D007262:Infusions, Intravenous; D009049:Motorcycles; D017211:Treatment Failure
chemical_list: D004164:Diphosphonates