title: [Medication review for dementia patients].
abstract: Due to demographic changes we are faced with several challenges as an increasing prevalence of dementia patients. We report on a medication review of a patient with Alzheimer's disease as well as Lewy body dementia. The intake of risperidone was interrupted instead of a dose reduction which was recommended by the psychiatrist to improve mobility. As an adverse event the patient developed serious psychiatric symptoms which were treated in an acute care facility. We discussed several alternative treatment options (pipamperon, melperon, haloperidol, risperidone, clozapine, olanzapine, aripiprazol, and quetiapin) in a case conference. Due to a short half life period and insignificant anticholinergic effects we decided to choose quetiapin. Despite a small number of taken drugs we identified several potential drug related problems which were solved in a multipartite health care professional team.
authors.affiliation: Ernst-Moritz-Arndt-Universität Greifswald, Institut für Pharmazie, Friedrich-Ludwig-Jahn-Strasse 17, 17487 Greifswald.
authors.forename: Karl-Peter
authors.initials: KP
authors.lastname: Jahns
authors.forename: Ingo
authors.initials: I
authors.lastname: Kilimann
authors.forename: Christoph A
authors.initials: CA
authors.lastname: Ritter
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Hoffmann
authors.forename: Stefan J
authors.initials: SJ
authors.lastname: Teipel
authors.forename: Thomas
authors.initials: T
authors.lastname: Fiss
mesh_terms: D000368:Aged; D000375:Aging / Q000502:physiology; D000544:Alzheimer Disease / Q000188:drug therapy; D014150:Antipsychotic Agents / Q000493:pharmacokinetics / Q000627:therapeutic use*; D003704:Dementia / Q000188:drug therapy* / Q000209:etiology; D006801:Humans; D020961:Lewy Body Disease / Q000188:drug therapy; D008875:Middle Aged; D020734:Parkinsonian Disorders / Q000150:complications / Q000188:drug therapy / Q000523:psychology; D011618:Psychotic Disorders / Q000188:drug therapy
chemical_list: D014150:Antipsychotic Agents