title: Cross-reactivity of Malaysian rat cytomegalovirus strains with its human counterpart.
abstract: This study probes into the prospect of cross-reactivity of HCMV with RCMV which   has not been acknowledged to date. We describe the uncovering of a protein with an estimated   size of between 61-68 kDa from local RCMV strains which reacted with HCMV positive sera.   Our findings are a first disclosure of a plausible immunological cross-reactivity between   RCMV with its human counterpart which grounds substantial interest implying existence of   conserved determinants between rat and human CMV polypeptides. The cross-reactive protein   most likely represents an enveloped glycoprotein, though the precise identification and its   degree of similarity needs to be evidently defined and further elucidated in forthcoming   experiments.
authors.affiliation: Department of Veterinary Pathology and Microbiology, Faculty of Veterinary Medicine, Universiti Putra Malaysia, 43400, UPM, Serdang, Selangor, Malaysia.
authors.forename: S N
authors.initials: SN
authors.lastname: Camalxaman
authors.forename: N A
authors.initials: NA
authors.lastname: Zeenathul
authors.forename: Y W
authors.initials: YW
authors.lastname: Quah
authors.forename: H S
authors.initials: HS
authors.lastname: Loh
authors.forename: H
authors.initials: H
authors.lastname: Zuridah
authors.forename: A R
authors.initials: AR
authors.lastname: Sheikh-Omar
authors.forename: M L
authors.initials: ML
authors.lastname: Mohd-Azmi
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000276:immunology*; D002460:Cell Line; D003429:Cross Reactions; D003587:Cytomegalovirus / Q000276:immunology*; D004591:Electrophoresis, Polyacrylamide Gel; D006801:Humans; D008970:Molecular Weight; D018146:Muromegalovirus / Q000276:immunology*; D051381:Rats; D014764:Viral Proteins / Q000737:chemistry / Q000276:immunology*
chemical_list: D000914:Antibodies, Viral; D014764:Viral Proteins