title: Comparison of nerve content in removed parametrial tissue after classic radical hysterectomy and nerve-sparing radical hysterectomy--histologic evaluation.
abstract: OBJECTIVE
  The aim of this study was to find whether nerve-sparing radical hysterectomy resulted in a lower amount of nerves in the removed parametrial tissue.
  
  
  METHODS
  Histological specimens from nerve-sparing radical hysterectomy (28 cases) were compared with those obtained after classic radical hysterectomy (26 cases). Width of the parametria and vaginal cuff were measured. Using a point counting technique, nerve areal density was determined in cross sections of resected parametria at 0.5 cm (A), 1 cm (B), 1.5 cm (C) from the cervix.
  
  
  RESULTS
  The width of the resected parametria was smaller in the study group (right side p < 0.013; left side; p < 0.011). The nerve areal density in the lateral part of the right parametrium was lower in the study group (p < 0.01) (Student's t-test). CCONCLUSION: Modified radical hysterectomy is less radical and is nerve-sparing.
authors.affiliation: Department of Obstetrics and Gynecology, University Medical Centre Ljubljana, Ljubljana, Slovenia. matija.barbic@guest.arnes.si
authors.forename: M
authors.initials: M
authors.lastname: Barbic
authors.forename: S
authors.initials: S
authors.lastname: Rakar
authors.forename: A
authors.initials: A
authors.lastname: Levicnik
authors.forename: A B
authors.initials: AB
authors.lastname: Di Stefano
mesh_terms: D017024:Chemotherapy, Adjuvant; D005260:Female; D006801:Humans; D007044:Hysterectomy / Q000379:methods*; D008207:Lymphatic Metastasis; D009367:Neoplasm Staging; D059351:Organ Sparing Treatments; D018714:Radiotherapy, Adjuvant; D015996:Survival Rate; D014555:Urination Disorders / Q000517:prevention & control; D002583:Uterine Cervical Neoplasms / Q000473:pathology* / Q000628:therapy*; D014599:Uterus / Q000033:anatomy & histology / Q000294:innervation* / Q000601:surgery