title: Elucidation of a novel pathogenomic mechanism using genome-wide long mate-pair sequencing of a congenital t(16;21) in a series of three RUNX1-mutated FPD/AML pedigrees.
authors.forename: A
authors.initials: A
authors.lastname: Buijs
authors.forename: M
authors.initials: M
authors.lastname: Poot
authors.forename: S
authors.initials: S
authors.lastname: van der Crabben
authors.forename: B
authors.initials: B
authors.lastname: van der Zwaag
authors.forename: E
authors.initials: E
authors.lastname: van Binsbergen
authors.forename: M J
authors.initials: MJ
authors.lastname: van Roosmalen
authors.forename: M
authors.initials: M
authors.lastname: Tavakoli-Yaraki
authors.forename: O
authors.initials: O
authors.lastname: de Weerdt
authors.forename: H K
authors.initials: HK
authors.lastname: Nieuwenhuis
authors.forename: M
authors.initials: M
authors.lastname: van Gijn
authors.forename: W P
authors.initials: WP
authors.lastname: Kloosterman
mesh_terms: D002885:Chromosomes, Human, Pair 16 / Q000235:genetics*; D002891:Chromosomes, Human, Pair 21 / Q000235:genetics*; D050676:Core Binding Factor Alpha 2 Subunit / Q000235:genetics*; D005260:Female; D020022:Genetic Predisposition to Disease; D015894:Genome, Human; D059014:High-Throughput Nucleotide Sequencing; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000151:congenital / Q000235:genetics* / Q000473:pathology*; D008297:Male; D009154:Mutation / Q000235:genetics*; D010375:Pedigree; D014178:Translocation, Genetic
chemical_list: D050676:Core Binding Factor Alpha 2 Subunit; C493728:RUNX1 protein, human