title: Otomycosis in immunocompetent and immunocompromised patients: comparative study and literature review.
abstract: A comparative clinical study was carried out that included 50 cases of otomycosis in immunocompetent patients and 50 cases of otomycosis in immunocompromised patients. Clinical presentation, predisposing factors, mycologic profile, and treatment outcomes were compared. Aspergillus spp were the most commonly isolated fungi in the immunocompetent group, and Candida albicans in the immunocompromised group. Bilateral involvement was more common in the immunocompromised group. All the patients were treated with topical clotrimazole ear drops. Four patients in the immunocompromised group did not respond to treatment with clotrimazole but were treated successfully with fluconazole ear drops. Three patients had a small tympanic membrane perforation due to otomycosis.
authors.affiliation: Department of ENT, Victoria Hospital and Bangalore Medical College and Research Institute, #716, 10th Cross, 5th Main, M.C. Layout, Vijayangar, Bangalore-560 040, Karnataka, India. drbviswanatha@yahoo.co.in
authors.forename: Borlingegowda
authors.initials: B
authors.lastname: Viswanatha
authors.forename: Dadarao
authors.initials: D
authors.lastname: Sumatha
authors.forename: Maliyappanahalli Siddappa
authors.initials: MS
authors.lastname: Vijayashree
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000935:Antifungal Agents / Q000627:therapeutic use; D001230:Aspergillus; D002176:Candida albicans; D003022:Clotrimazole / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007121:Immunocompetence; D016867:Immunocompromised Host; D008297:Male; D008875:Middle Aged; D059249:Otomycosis / Q000188:drug therapy / Q000276:immunology* / Q000382:microbiology; D055815:Young Adult
chemical_list: D000935:Antifungal Agents; D003022:Clotrimazole