title: A convenient and mild chromatography-free method for the purification of the products of Wittig and Appel reactions.
abstract: A mild method for the facile removal of phosphine oxide from the crude products of Wittig and Appel reactions is described. Work-up with oxalyl chloride to generate insoluble chlorophosphonium salt (CPS) yields phosphorus-free products for a wide variety of these reactions. The CPS product can be further converted into phosphine.
authors.affiliation: Centre for Synthesis and Chemical Biology, School of Chemistry and Chemical Biology, University College Dublin, Belfield, Dublin 4, Ireland.
authors.forename: Peter A
authors.initials: PA
authors.lastname: Byrne
authors.forename: Kamalraj V
authors.initials: KV
authors.lastname: Rajendran
authors.forename: Jimmy
authors.initials: J
authors.lastname: Muldoon
authors.forename: Declan G
authors.initials: DG
authors.lastname: Gilheany