title: Use of plethysmographic variability index derived from the Massimo(®)  pulse oximeter to predict fluid or preload responsiveness: a systematic review and meta-analysis.
abstract: This systematic review and meta-analysis assessed the accuracy of plethysmographic variability index derived from the Massimo(®)  pulse oximeter to predict preload responsiveness in peri-operative and critically ill patients. A total of 10 studies were retrieved from the literature, involving 328 patients who met the selection criteria. Overall, the diagnostic odds ratio (16.0; 95% CI 5-48) and area under the summary receiver operating characteristic curve (0.87; 95% CI 0.78-0.95) for plethysmographic variability index to predict fluid or preload responsiveness was very good, but significant heterogeneity existed. This could be explained by a lower accuracy of plethysmographic variability index in spontaneously breathing or paediatric patients and those studies that used pre-load challenges other than colloid fluid. The results indicate specific directions for future studies.
authors.affiliation: Department of Surgery, Nanjing University School of Medicine, Nanjing, China.
authors.forename: J Y
authors.initials: JY
authors.lastname: Yin
authors.forename: K M
authors.initials: KM
authors.lastname: Ho
mesh_terms: D003422:Critical Care / Q000379:methods; D005440:Fluid Therapy / Q000379:methods*; D006801:Humans; D010092:Oximetry / Q000295:instrumentation / Q000379:methods; D019990:Perioperative Care / Q000379:methods; D010991:Plethysmography / Q000379:methods*