title: Shorter time between opioid prescriptions associated with reduced work disability among acute low back pain opioid users.
abstract: OBJECTIVE
  To explore whether average time between opioid prescriptions is associated with shorter time off work.
  
  
  METHODS
  Claims from 1422 work-related acute low back pain cases with at least two opioid prescriptions during the first month and at least 1 day of disability after the first month. Intended duration of first month opioid prescriptions was computed and averaged.
  
  
  RESULTS
  After controlling for demographic and severity indicators, each additional week between opioid prescriptions predicted 14% longer disability (risk ratio, 1.14; 95% confidence interval, 1.06 to 1.22). This association remained robust in sensitivity analyses.
  
  
  CONCLUSIONS
  Fewer days between opioid prescriptions were associated with shorter time off work. The mechanism of this effect is unknown but may be related to provider's close monitoring of the patient's pain and function, as well as addressing barriers that may prevent workers from returning to work.
authors.affiliation: Center for Disability Research at Liberty Mutual Research Institute for Safety, Boston, MA, USA. Manuel_Cifuentes@uml.edu
authors.forename: Manuel
authors.initials: M
authors.lastname: Cifuentes
authors.forename: Ryan
authors.initials: R
authors.lastname: Powell
authors.forename: Barbara
authors.initials: B
authors.lastname: Webster
mesh_terms: D000328:Adult; D000701:Analgesics, Opioid / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D017116:Low Back Pain / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D055656:Prescriptions; D018582:Sick Leave; D014942:Workers' Compensation / Q000706:statistics & numerical data
chemical_list: D000701:Analgesics, Opioid