title: [What reasonable applications for regional citrate anticoagulation in renal replacement therapy?].
abstract: Regional citrate anticoagulation of the extracorporeal circuits (CRA) experienced considerable growth over the past decade. This development is partly explained by the significant progresses made in the field of bioengineering. These allow a secure administration of citrate, while an increasing availability of ionized calcium measurement at the bedside allows reactivity in monitoring the treatment. An increasing severity of the medical condition of patients requiring blood purification treatment gives more contrast to the profile of patient who may benefit from a CRA. If some methods of renal replacement therapy are well suited to this mode of anticoagulation, others are, to date, only at the stage of development and are applied under close medical supervision.
authors.affiliation: Service de néphrologie et hypertension, Départment de médecine interne CHUV, Lausanne. sebastien.kissling@chuv.ch
authors.forename: S
authors.initials: S
authors.lastname: Kissling
authors.forename: P
authors.initials: P
authors.lastname: Wilson
authors.forename: C
authors.initials: C
authors.lastname: Ridel
authors.forename: M
authors.initials: M
authors.lastname: Burnier
authors.forename: B
authors.initials: B
authors.lastname: Vogt
mesh_terms: D000925:Anticoagulants / Q000008:administration & dosage*; D019343:Citric Acid / Q000008:administration & dosage*; D006801:Humans; D036502:Infusions, Intralesional; D007688:Kidneys, Artificial; D008954:Models, Biological; D006435:Renal Dialysis / Q000379:methods / Q000706:statistics & numerical data; D017582:Renal Replacement Therapy / Q000379:methods* / Q000706:statistics & numerical data; D057832:Watchful Waiting
chemical_list: D000925:Anticoagulants; D019343:Citric Acid