title: IgG anti-toxoplasma antibodies among asymptomatic HIV-infected patients in Marrakesh-Morocco.
abstract: Detection and monitoring of anti-Toxoplasma gondii antibodies are of a great interest among human immunodeficiency virus (HIV)-infected patients, since cerebral toxoplasmosis is a life-threatening opportunistic infection within this vulnerable population. The IgG anti-T. gondii seroprevalence was assessed in 95 asymptomatic HIV-infected adults living in Marrakesh city and its surrounding areas. Our results showed a seroprevalence of 62.1%, which is high compared to most other countries. The mean of CD(4+) T-cells count of involved patients was 381.9cells/μl. Given these results, HIV-infected patients in Marrakesh region could be at high risk to develop toxoplasmosis disease, especially when CD(4+) T-cells count falls below 100cells/μl. Accordingly, there is a serious need of widening antiretroviral therapy and chemoprophylaxis against toxoplasmosis, when indicated, to ovoid toxoplasmosis reactivation among this population.
authors.affiliation: Laboratory of Mycology and Parasitology, Hôpital Ibn Tofaïl, centre hospitalier universitaire Mohammed VI, Marrakech, Morocco. amal.add@gmail.com
authors.forename: Amal
authors.initials: A
authors.lastname: Addebbous
authors.forename: Latifa
authors.initials: L
authors.lastname: Adarmouch
authors.forename: Abdelali
authors.initials: A
authors.lastname: Tali
authors.forename: Majda
authors.initials: M
authors.lastname: Laboudi
authors.forename: Mohamed
authors.initials: M
authors.lastname: Amine
authors.forename: Lahcen
authors.initials: L
authors.lastname: Aajly
authors.forename: Mohamed
authors.initials: M
authors.lastname: Rhajaoui
authors.forename: Laila
authors.initials: L
authors.lastname: Chabaa
authors.forename: Laila
authors.initials: L
authors.lastname: Zougaghi
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000453:epidemiology* / Q000469:parasitology; D000328:Adult; D000913:Antibodies, Protozoan / Q000097:blood*; D058070:Asymptomatic Diseases / Q000453:epidemiology*; D018791:CD4 Lymphocyte Count; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D008297:Male; D008875:Middle Aged; D009018:Morocco / Q000453:epidemiology; D016036:Seroepidemiologic Studies; D014122:Toxoplasma / Q000276:immunology*; D014123:Toxoplasmosis / Q000453:epidemiology* / Q000469:parasitology
chemical_list: D000913:Antibodies, Protozoan; D007074:Immunoglobulin G