title: Symptom profile and etiology of delirium in a referral population in northern india: factor analysis of the DRS-R98.
abstract: Delirium is understudied in developing countries, where there tends to be a lower proportion of older persons and comorbid dementia. The authors assessed 100 consecutive cases of DSM-IV delirium (patients' mean age: 44.4 [standard deviation: 19.4] years; mean DRS-R98 score: 25.6 [3.6]) referred to an adult Consultation-Liaison Psychiatry service in Northern India. Disturbances of attention, orientation, visuospatial ability, and sleep disturbance were the most frequent symptoms, followed by language, thought-process abnormality, and motor agitation. A three-factor solution was identified, representing domains for cognition, higher-order thinking, and circadian rhythm/psychosis. These domains can guide studies addressing the relationship between symptom profile, therapeutic needs, and outcomes and are consistent with core domains previously identified in other countries.
authors.affiliation: Dept. of Psychiatry, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
authors.forename: Surendra K
authors.initials: SK
authors.lastname: Mattoo
authors.forename: Sandeep
authors.initials: S
authors.lastname: Grover
authors.forename: Kaustav
authors.initials: K
authors.lastname: Chakravarty
authors.forename: Paula T
authors.initials: PT
authors.lastname: Trzepacz
authors.forename: David J
authors.initials: DJ
authors.lastname: Meagher
authors.forename: Nitin
authors.initials: N
authors.lastname: Gupta
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001289:Attention Deficit Disorder with Hyperactivity / Q000209:etiology*; D002940:Circadian Rhythm / Q000502:physiology; D003072:Cognition Disorders / Q000209:etiology; D003693:Delirium / Q000150:complications / Q000453:epidemiology / Q000209:etiology; D039721:Diagnostic and Statistical Manual of Mental Disorders; D005163:Factor Analysis, Statistical; D005260:Female; D006801:Humans; D007194:India / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D010468:Perceptual Disorders / Q000209:etiology; D011569:Psychiatric Status Rating Scales; D012017:Referral and Consultation; D012720:Severity of Illness Index; D012893:Sleep Wake Disorders / Q000209:etiology; D014796:Visual Perception / Q000502:physiology; D055815:Young Adult