title: An organocatalytic Michael-aldol cascade: formal [3+2] annulation to construct enantioenriched spirocyclic oxindole derivatives.
abstract: An efficient organocatalytic Michael-aldol cascade reaction for the asymmetric synthesis of spirocyclic oxindole derivatives fused with tetrahydrothiophenes has been developed through a formal [3+2] annulation strategy.
authors.affiliation: Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, 152 Luoyu Road, Wuhan, Hubei 430079, China.
authors.forename: Shu-Wen
authors.initials: SW
authors.lastname: Duan
authors.forename: Yang
authors.initials: Y
authors.lastname: Li
authors.forename: Yi-Yin
authors.initials: YY
authors.lastname: Liu
authors.forename: You-Quan
authors.initials: YQ
authors.lastname: Zou
authors.forename: De-Qing
authors.initials: DQ
authors.lastname: Shi
authors.forename: Wen-Jing
authors.initials: WJ
authors.lastname: Xiao
mesh_terms: D000447:Aldehydes / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D007211:Indoles / Q000737:chemistry*; D000078183:Oxindoles; D013141:Spiro Compounds / Q000737:chemistry*; D013237:Stereoisomerism; D013876:Thiophenes / Q000737:chemistry
chemical_list: D000447:Aldehydes; D007211:Indoles; D000078183:Oxindoles; D013141:Spiro Compounds; D013876:Thiophenes; C022960:2-oxindole; C116609:3-hydroxybutanal