title: Synthesis of polysaccharide-b-PEG block copolymers by oxime click.
abstract: The oxime click reaction is shown to be a straightforward methodology for the synthesis of poly(ethylene glycol) (PEG)-polysaccharide diblock copolymers. The method is applicable to unmodified polysaccharides with a reductive end as demonstrated for dextran, hyaluronic acid and chitosan. Notably the oxime click reaction is applied for the first time to the end modification of polysaccharides.
authors.affiliation: Makromolekulare Chemie II, Universität Bayreuth, 95440 Bayreuth, Germany. ramon.novoa-carballal@uni-bayreuth.de
authors.forename: Ramon
authors.initials: R
authors.lastname: Novoa-Carballal
authors.forename: Axel H E
authors.initials: AH
authors.lastname: Müller
mesh_terms: D057930:Click Chemistry; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010091:Oximes / Q000737:chemistry; D011092:Polyethylene Glycols / Q000737:chemistry*; D011134:Polysaccharides / Q000737:chemistry*
chemical_list: D010091:Oximes; D011134:Polysaccharides; D011092:Polyethylene Glycols