title: Nasal eschar:  a warning sign of potentially fatal invasive fungal sinusitis in immunocompromised children.
abstract: Most invasive fungal sinusitis occurs in immunocompromised adult patients. We present the case study of a 12-year-old boy diagnosed with acute myeloblastic leukemia undergoing chemotherapy. He developed a progressive darkening discoloration over the dorsum of the nose that turned into an eschar. Nasal endoscopy revealed extensive necrotic tissue in the nasal cavity mucosa, inferior and middle turbinates, and septal cartilage that extended to the eschar of the skin over the nasal dorsum. Histopathology showed aspergillus invasive fungal rhinosinusitis.
authors.affiliation: Hospital Sultanah Bahiyah, Kedah, Malaysia. drnurlizaidris@yahoo.com
authors.forename: Nurliza
authors.initials: N
authors.lastname: Idris
authors.forename: Lynne H Y
authors.initials: LH
authors.lastname: Lim
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000009:adverse effects*; D001228:Aspergillosis / Q000139:chemically induced / Q000382:microbiology / Q000473:pathology; D002648:Child; D017809:Fatal Outcome; D006801:Humans; D016867:Immunocompromised Host; D015470:Leukemia, Myeloid, Acute / Q000188:drug therapy* / Q000276:immunology / Q000382:microbiology / Q000473:pathology; D008297:Male; D009296:Nasal Cavity / Q000382:microbiology / Q000473:pathology; D012220:Rhinitis / Q000139:chemically induced / Q000382:microbiology / Q000473:pathology; D012852:Sinusitis / Q000139:chemically induced / Q000382:microbiology / Q000473:pathology