title: A unified access to diverse heteroaromatic scaffolds using the radical chemistry of xanthates.
abstract: The degenerate transfer of xanthates allows generally difficult radical transformations, such as intermolecular additions to unactivated alkenes and cyclisations onto aromatic and heteroaromatic rings, to be accomplished under very practical experimental conditions. This translates into numerous approaches for the construction or modification of heteroaromatic structures. The present report aims to provide a brief overview of the various synthetic possibilities, with particular emphasis on medicinally interesting families of compounds.
authors.affiliation: Laboratoire de Synthèse Organique, UMR 7652, Ecole Polytechnique, 91128 Palaiseau, France.
authors.forename: Myriem
authors.initials: M
authors.lastname: El Qacemi
authors.forename: Laurent
authors.initials: L
authors.lastname: Petit
authors.forename: Béatrice
authors.initials: B
authors.lastname: Quiclet-Sire
authors.forename: Samir Z
authors.initials: SZ
authors.lastname: Zard
mesh_terms: D060326:Chemistry Techniques, Synthetic / Q000379:methods*; D005609:Free Radicals / Q000737:chemistry*; D009584:Nitrogen / Q000737:chemistry; D011083:Polycyclic Compounds / Q000138:chemical synthesis / Q000737:chemistry; D014970:Xanthines / Q000138:chemical synthesis* / Q000737:chemistry*
chemical_list: D005609:Free Radicals; D011083:Polycyclic Compounds; D014970:Xanthines; D009584:Nitrogen