title: Dissemination of pCT-like IncK plasmids harboring CTX-M-14 extended-spectrum β-lactamase among clinical Escherichia coli isolates in the United Kingdom.
abstract: IncK plasmids encoding CTX-M-14 extended-spectrum β-lactamase (ESBL) and highly related to plasmid pCT were detected in 13 of 67 (19%) human clinical isolates of Escherichia coli with a group 9 CTX-M-type ESBL from the United Kingdom and in 2 quality assurance isolates. None of these E. coli strains was related to the cattle strain from which pCT was originally characterized.
authors.affiliation: Antibiotic Resistance Monitoring and Reference Laboratory, Health Protection Agency, London, United Kingdom. Hiran.dhanji@hpa.org.uk
authors.forename: Hiran
authors.initials: H
authors.lastname: Dhanji
authors.forename: Parmina
authors.initials: P
authors.lastname: Khan
authors.forename: Jennifer L
authors.initials: JL
authors.lastname: Cottell
authors.forename: Laura J V
authors.initials: LJ
authors.lastname: Piddock
authors.forename: Jiancheng
authors.initials: J
authors.lastname: Zhang
authors.forename: David M
authors.initials: DM
authors.lastname: Livermore
authors.forename: Neil
authors.initials: N
authors.lastname: Woodford
mesh_terms: D004926:Escherichia coli / Q000145:classification / Q000201:enzymology* / Q000235:genetics*; D010802:Phylogeny; D010957:Plasmids / Q000235:genetics*; D006113:United Kingdom; D001618:beta-Lactamases / Q000235:genetics / Q000378:metabolism*
chemical_list: C456080:beta-lactamase CTX-M-14; D001618:beta-Lactamases