title: MtsslWizard: In Silico Spin-Labeling and Generation of Distance Distributions in PyMOL.
abstract: MtsslWizard is a computer program, which operates as a plugin for the PyMOL molecular graphics system. MtsslWizard estimates distances between spin labels on proteins quickly with user-configurable options through a simple graphical interface. In default mode, the program searches for ensembles of possible MTSSL conformations that do not clash with a static model of the protein. Once conformations are assigned, distance distributions between two or more ensembles are calculated, displayed, and can be exported to other software. The program's use is evaluated in a number of challenging test cases and its strengths and weaknesses evaluated. The benefits of the program are its accuracy and simplicity. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s00723-012-0314-0) contains supplementary material, which is available to authorized users.
authors.affiliation: Biomedical Sciences Research Complex, The University of St. Andrews, Fife, KY16 9ST UK.
authors.forename: Gregor
authors.initials: G
authors.lastname: Hagelueken
authors.forename: Richard
authors.initials: R
authors.lastname: Ward
authors.forename: James H
authors.initials: JH
authors.lastname: Naismith
authors.forename: Olav
authors.initials: O
authors.lastname: Schiemann