title: Near infrared spectroscopy patents for the physicochemical characterization of nanomaterials: the road from production to routine high-throughput quality control.
abstract: The measurement of the physical and chemical ("physicochemical") properties of nanomaterials used in industry and science including chemistry, pharmacy, medicine, toxicology, etc., is time-consuming, expensive and requires a lot of experience of a well trained lab staff. Near-infrared spectroscopy (NIR; 4.000-12.000 cm(-1)), working in the wavelength region with the highest IR energy, allows obtaining multifactorial information of the material under investigation due to the occurrence of a high number of combination and overtone vibrations. Coupling of an optimized and well-designed measurement technique with multivariate data analysis (MVA) leads to a non-destructive, fast, reliable and robust novel NIR technique for the fast and non-invasive physicochemical characterization, which is suitable for high-throughput quality control due to the short analyses times of only a few seconds. In the following chapters, the patented basic NIR techniques full-filling these aims are introduced, described, summarized and critically discussed.
authors.affiliation: Institute of Analytical Chemistry and Radiochemistry, Leopold-Franzens University, Innsbruck, Austria. Christian.W.Huck@uibk.ac.at
authors.forename: C W
authors.initials: CW
authors.lastname: Huck
authors.forename: C
authors.initials: C
authors.lastname: Pezzei
authors.forename: V A
authors.initials: VA
authors.lastname: Huck-Pezzei
authors.forename: J D
authors.initials: JD
authors.lastname: Pallua
authors.forename: S A
authors.initials: SA
authors.lastname: Schoenbichler
authors.forename: L K
authors.initials: LK
authors.lastname: Bittner
authors.forename: G K
authors.initials: GK
authors.lastname: Bonn
mesh_terms: D037741:Fullerenes / Q000737:chemistry; D049329:Nanostructures / Q000737:chemistry* / Q000592:standards; D037742:Nanotubes, Carbon / Q000737:chemistry; D010330:Patents as Topic; D004364:Pharmaceutical Preparations / Q000737:chemistry; D025341:Principal Component Analysis; D011786:Quality Control; D017640:Silicates / Q000737:chemistry; D019265:Spectroscopy, Near-Infrared / Q000592:standards
chemical_list: D037741:Fullerenes; D037742:Nanotubes, Carbon; D004364:Pharmaceutical Preparations; D017640:Silicates; C069837:fullerene C60