title: Skin exposure to deodorants/antiperspirants in aerosol form.
abstract: Many cosmetic products are available in spray form. Even though the principal targets of these products are the skin and hair, spraying leads to the partitioning of the product between the target and the surrounding air. In the previous COLIPA study (Hall et al., 2007) the daily use of deodorant/antiperspirant (Deo/AP) in spray form was quantified in terms of the amount of product dispensed from the spray can, without specifically quantifying the product fraction reaching the skin during use. Results of the present study provide this additional information, necessary for a reliable safety assessment of sprayed Deo/AP products. In a novel experimental approach the information obtained from real-life movement analysis (automated motion imaging) of volunteers using their own products was integrated with the aerosol cloud sampling data obtained from the same products, leading to the computation of the product deposited on the skin. The 90th percentile values, expressed as percent deposition relative to the can weight loss after spraying, are 23.5% and 11.4% for ethanol-based and non-ethanol-based products, respectively. Additionally, the study has generated data on the skin area covered by the products, spray duration time, spray angle and spray distance from the skin.
authors.affiliation: Henkel AG & Co. KGaA, Corporate Product Safety-Human Safety Assessment, Düsseldorf, Germany.
authors.forename: W
authors.initials: W
authors.lastname: Steiling
authors.forename: P
authors.initials: P
authors.lastname: Buttgereit
authors.forename: B
authors.initials: B
authors.lastname: Hall
authors.forename: L
authors.initials: L
authors.lastname: O'Keeffe
authors.forename: B
authors.initials: B
authors.lastname: Safford
authors.forename: S
authors.initials: S
authors.lastname: Tozer
authors.forename: M
authors.initials: M
authors.lastname: Coroama
mesh_terms: D000328:Adult; D000336:Aerosols; D000465:Algorithms; D051520:Antiperspirants / Q000032:analysis*; D003198:Computer Simulation; D003358:Cosmetics; D003836:Deodorants / Q000032:analysis*; D000431:Ethanol; D005260:Female; D006184:Habits; D006801:Humans; D007259:Infrared Rays; D008297:Male; D008875:Middle Aged; D008962:Models, Theoretical; D012867:Skin / Q000737:chemistry*; D012997:Solvents; D055815:Young Adult
chemical_list: D000336:Aerosols; D051520:Antiperspirants; D003358:Cosmetics; D003836:Deodorants; D012997:Solvents; D000431:Ethanol