title: NF-κB subunit specificity in hemopoiesis.
abstract: Although the diverse functions served by the nuclear factor-κB (NF-κB) pathway in virtually all cell types are typically employed to deal with stress responses, NF-κB transcription factors also play key roles in the development of hemopoietic cells. This review focuses on how NF-κB transcription factors control various aspects of thymic T-cell and myeloid cell differentiation that include its roles in hemopoietic precursors, conventional αβ T cells, CD4(+) regulatory T cells, natural killer T cells, γδ T cells, macrophages, and dendritic cells.
authors.affiliation: Burnet Institute, Prahran, Vic., Australia. gerondakis@burnet.edu.au and
authors.forename: Steve
authors.initials: S
authors.lastname: Gerondakis
authors.forename: Ashish
authors.initials: A
authors.lastname: Banerjee
authors.forename: George
authors.initials: G
authors.lastname: Grigoriadis
authors.forename: Ajithkumar
authors.initials: A
authors.lastname: Vasanthakumar
authors.forename: Raffi
authors.initials: R
authors.lastname: Gugasyan
authors.forename: Tom
authors.initials: T
authors.lastname: Sidwell
authors.forename: Raelene J
authors.initials: RJ
authors.lastname: Grumont
mesh_terms: D000818:Animals; D019070:Cell Lineage; D006410:Hematopoiesis / Q000502:physiology*; D006801:Humans; D022423:Myeloid Cells / Q000378:metabolism; D016328:NF-kappa B / Q000737:chemistry* / Q000378:metabolism*; D021122:Protein Subunits / Q000378:metabolism*; D013601:T-Lymphocytes / Q000378:metabolism; D060168:Thymocytes / Q000378:metabolism
chemical_list: D016328:NF-kappa B; D021122:Protein Subunits