title: Fluorescent microscopic study of endocytosis of nanoparticles by platelets.
abstract: We propose a method of precise measurement of the content of nanoparticles carrying a fluorescent label in platelets. Examination under a broadband filter does not allow distinguishing platelets containing and not containing nanoparticles despite different staining of platelets and nanoparticles. Print Screen image of the sample made at the moment of sample motion divides the colors of nanoparticles and platelets and yields two clear-cut spots of different colors on the monitor indicating the presence of nanoparticles in platelets.
authors.affiliation: Institute of General Pathology and Pathophysiology, Russian Academy of Sciences, Moscow, Russia. lrrp@mail.ru
authors.forename: A A
authors.initials: AA
authors.lastname: Pal'tsyn
authors.forename: S V
authors.initials: SV
authors.lastname: Komissarova
authors.forename: A P
authors.initials: AP
authors.lastname: Kaplun
mesh_terms: D001792:Blood Platelets / Q000378:metabolism* / Q000648:ultrastructure; D004705:Endocytosis; D006801:Humans; D008854:Microscopy, Electron; D008856:Microscopy, Fluorescence / Q000379:methods*; D053758:Nanoparticles