title: Diffuse large cell non-Hodgkin lymphoma with pituitary and bilateral adrenal involvement.
abstract: We describe an elderly male patient who presented with fever of unknown origin and refractory hyponatraemia. Following (18) fluorine-fluorodeoxyglucose positron emission tomography/computed tomography scan and core adrenal biopsy, the diagnosis of diffuse large B-cell non-Hodgkin lymphoma with pituitary and bilateral adrenal involvement was confirmed. After chemotherapy, his symptoms resolved, and all the lesions shrank significantly.
authors.affiliation: Department of Endocrinology, Chinese PLA General Hospital, Beijing, China.
authors.forename: X-L
authors.initials: XL
authors.lastname: Wang
authors.forename: Z-H
authors.initials: ZH
authors.lastname: Lü
authors.forename: Y-M
authors.initials: YM
authors.lastname: Mu
authors.forename: J-T
authors.initials: JT
authors.lastname: Dou
authors.forename: J-M
authors.initials: JM
authors.lastname: Lu
authors.forename: W-W
authors.initials: WW
authors.lastname: Zhong
authors.forename: C-Y
authors.initials: CY
authors.lastname: Pan
mesh_terms: D000311:Adrenal Glands / Q000000981:diagnostic imaging / Q000473:pathology*; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use; D003520:Cyclophosphamide / Q000008:administration & dosage / Q000009:adverse effects; D003907:Dexamethasone / Q000008:administration & dosage / Q000009:adverse effects; D004317:Doxorubicin / Q000008:administration & dosage / Q000009:adverse effects; D017809:Fatal Outcome; D005335:Fever of Unknown Origin / Q000209:etiology; D006801:Humans; D007010:Hyponatremia / Q000209:etiology / Q000503:physiopathology; D016403:Lymphoma, Large B-Cell, Diffuse / Q000150:complications / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology*; D008297:Male; D008727:Methotrexate / Q000008:administration & dosage / Q000009:adverse effects; D064847:Multimodal Imaging; D010902:Pituitary Gland / Q000000981:diagnostic imaging / Q000473:pathology*; D010913:Pituitary-Adrenal System / Q000503:physiopathology; D049268:Positron-Emission Tomography; D011241:Prednisone / Q000008:administration & dosage / Q000009:adverse effects; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography; D014750:Vincristine / Q000008:administration & dosage / Q000009:adverse effects
chemical_list: D014750:Vincristine; D003907:Dexamethasone; D004317:Doxorubicin; D003520:Cyclophosphamide; D011241:Prednisone; D008727:Methotrexate