title: Frequency of human papillomavirus types 16, 18, 31,  and 33 and sites of cervical lesions in gynecological patients from Recife,  Brazil.
abstract: Human papilloma virus (HPV) is a well-established  cause of cervical cancer. While many studies have been performed so far on HPV  viral biology, mode of infection and prevention measures, scanty information is  available on lesion sites of infected women and the incidence of viral types at  specific locations. We looked for a possible relationship between the most  common viral types (HPVs 16, 18, 31, 33) found in Recife, PE, Brazil, and  lesion sites. We examined 396 HPV-positive women at the Gynecological Unit of  the IMIP at Recife; 288 women were positive for HPV 16, 18, 31, or 33, present  as a single-virus type or as co-infection. HPV 16 was the most frequent virus  type found in the vulva, vagina, uterine cervix-vagina, and uterine cervix. HPV  31 was the second prevalent virus type in vulva, vagina, uterine cervix-vagina,  uterine cervix, and mole. HPVs 18 and 33 were present with similar frequencies  in the mole-vulva region. Among the co-infections, HPV 16/18 and HPV16/31 were  the most frequent in our study group, followed by HPV 16/33.
authors.affiliation: Laboratório de Citogenética, Universidade Estadual de Maringá, Maringá, PR, Brasil. mfbaldez@hotmail.com
authors.forename: M F P T
authors.initials: MF
authors.lastname: Baldez da Silva
authors.forename: V
authors.initials: V
authors.lastname: Guimarães
authors.forename: M A R
authors.initials: MA
authors.lastname: Silva
authors.forename: C M
authors.initials: CM
authors.lastname: Medeiros do Amaral
authors.forename: W
authors.initials: W
authors.lastname: Beçak
authors.forename: R C
authors.initials: RC
authors.lastname: Stocco
authors.forename: A C
authors.initials: AC
authors.lastname: Freitas
authors.forename: S
authors.initials: S
authors.lastname: Crovella
mesh_terms: D000293:Adolescent; D000328:Adult; D001938:Brazil / Q000453:epidemiology; D002584:Cervix Uteri / Q000473:pathology / Q000821:virology; D004279:DNA, Viral / Q000032:analysis; D005260:Female; D052162:Human papillomavirus 16 / Q000235:genetics / Q000302:isolation & purification*; D052161:Human papillomavirus 18 / Q000235:genetics / Q000302:isolation & purification*; D058952:Human papillomavirus 31 / Q000235:genetics / Q000302:isolation & purification*; D006801:Humans; D030361:Papillomavirus Infections / Q000453:epidemiology* / Q000821:virology*; D002577:Uterine Cervical Diseases / Q000473:pathology / Q000821:virology; D055815:Young Adult
chemical_list: D004279:DNA, Viral