title: Toxicity of biodegradable nanoscale preparations.
abstract: Nowadays, biodegradable nanoscale preparations such as liposomes, micelles, nanoparticles (NPs), and solid lipid nanoparticles (SLN) have attracted increasing attention from major researchers. Meanwhile the biosafety of the nanomaterials brings more and more attention. Toxicity of the biodegradable nanoscale preparations varies depending on their particle size, shape, surface structure, etc. This article aims to review the toxicity of the above-mentioned nanoscale preparations and the relative methodology. It may be significant for successful use of more nanoscale preparations in clinical practice.
authors.affiliation: State Key Laboratory of Oral Diseases, West China College of Stomatology, Sichuan University, No.14 3rd Sec. Ren Min Nan Road, Chengdu P.R. China.
authors.forename: Fan
authors.initials: F
authors.lastname: Jian
authors.forename: Yi
authors.initials: Y
authors.lastname: Zhang
authors.forename: Jing
authors.initials: J
authors.lastname: Wang
authors.forename: Kai
authors.initials: K
authors.lastname: Ba
authors.forename: Runyi
authors.initials: R
authors.lastname: Mao
authors.forename: Wenli
authors.initials: W
authors.lastname: Lai
authors.forename: Yunfeng
authors.initials: Y
authors.lastname: Lin
mesh_terms: D000818:Animals; D004337:Drug Carriers / Q000633:toxicity*; D006801:Humans; D008823:Micelles; D049329:Nanostructures / Q000633:toxicity*
chemical_list: D004337:Drug Carriers; D008823:Micelles