title: Preparation of trifluoromethyl-substituted aziridines with in situ generated CF3CHN2.
abstract: Direct access to trifluoromethyl-substituted aziridines through the use of a protocol in which trifluoromethyl diazomethane is generated in situ and subsequently undergoes addition to activated imines is reported.
authors.affiliation: Laboratorium für Organische Chemie, ETH Zürich, CH-8093 Zürich, Switzerland.
authors.forename: Stefan A
authors.initials: SA
authors.lastname: Künzi
authors.forename: Bill
authors.initials: B
authors.lastname: Morandi
authors.forename: Erick M
authors.initials: EM
authors.lastname: Carreira
mesh_terms: D001388:Aziridines / Q000138:chemical synthesis* / Q000737:chemistry; D020650:Combinatorial Chemistry Techniques; D003978:Diazomethane / Q000031:analogs & derivatives* / Q000737:chemistry*; D006845:Hydrocarbons, Fluorinated / Q000138:chemical synthesis* / Q000737:chemistry*; D007097:Imines / Q000737:chemistry; D015394:Molecular Structure
chemical_list: D001388:Aziridines; D006845:Hydrocarbons, Fluorinated; D007097:Imines; D003978:Diazomethane