title: [Effect of iron supplementation on iron deficiency anemia of childbearing age women in Shanghai].
abstract: OBJECTIVE
  To investigate the effect of iron supplementation on iron deficiency anemia of childbearing age women, and to find out the optimal amount of iron intake for maintaining their health.
  
  
  METHODS
  74 childbearing age women aged 21 to 45 years with anemia were randomly assigned to intervention or control group by hemoglobin content, and a iron nutrition packet (mainly composed of ferric pyrophosphate and ferrous fumarate, containing iron 8 mg) or a placebo packet was given daily for six months, respectively. Hemoglobin, serum ferritin, food frequency and 24h dietary recall survey were performed before intervention and three and six months after intervention.
  
  
  RESULTS
  Hemoglobin and serum ferritin of the intervention group were significantly higher (P < 0.01) than that in control group after six months. The number of women with hemoglobin > or = 120 g/L in intervention and control group was 15 (44.1%) and 5 (14.3%), respectively (P < 0.01). The number of women with serum ferritin > or = 15 micro g/L in intervention and control group was 11 (34.4%) and 4 (12.5%), respectively (P < 0.05). The average dietary iron intake was 14.0 mg/d, mainly from plant foods. There was a positive correlation of total iron intake (dietary iron plus iron supplements) with hemoglobin (r = 0.57, P < 0.01). More menstrual blood and dietary fiber were the risk factors for iron deficiency anemia (P < 0.05).
  
  
  CONCLUSIONS
  The anemic status in childbearing age women could be improved by providing iron 8 mg daily for six months consecutively. Daily dietary intake of iron 23.2 mg can meet the requirement of maintaining normal iron storage for childbearing age women.
authors.affiliation: Clinic Nutrition Center, Department of Clinical Laboratory, Huadong Hospital, Fudan University, Shanghai 200040, China. terrancewang2011@yeah.net
authors.forename: Zhengyuan
authors.initials: Z
authors.lastname: Wang
authors.forename: Jianqin
authors.initials: J
authors.lastname: Sun
authors.forename: Lu
authors.initials: L
authors.lastname: Wang
authors.forename: Min
authors.initials: M
authors.lastname: Zong
authors.forename: Yanqiu
authors.initials: Y
authors.lastname: Chen
authors.forename: Yifan
authors.initials: Y
authors.lastname: Lin
authors.forename: Danfeng
authors.initials: D
authors.lastname: Xu
authors.forename: Jingjing
authors.initials: J
authors.lastname: Jiang
authors.forename: Yiru
authors.initials: Y
authors.lastname: Pan
authors.forename: Jianhua
authors.initials: J
authors.lastname: Piao
authors.forename: Zhenwu
authors.initials: Z
authors.lastname: Huang
authors.forename: Xiaoguang
authors.initials: X
authors.lastname: Yang
mesh_terms: D000328:Adult; D018798:Anemia, Iron-Deficiency / Q000188:drug therapy*; D011756:Diphosphates / Q000627:therapeutic use*; D005260:Female; D005296:Ferrous Compounds / Q000627:therapeutic use*; D006801:Humans; D007501:Iron / Q000008:administration & dosage* / Q000627:therapeutic use; D008875:Middle Aged; D055815:Young Adult
chemical_list: D011756:Diphosphates; D005296:Ferrous Compounds; D007501:Iron; C049051:ferric pyrophosphate; C031621:ferrous fumarate