title: Tandem-type Pd(II)-catalyzed oxidative Heck reaction/intramolecular C-H amidation sequence: a novel route to 4-aryl-2-quinolinones.
abstract: A novel catalytic method for synthesizing 4-aryl-2-quinolinones is reported. The process involves two mechanistically independent, sequential Pd(II)-catalyzed reactions--the oxidative Heck reaction and the intramolecular C-H amidation--both of which smoothly proceed in the presence of a single catalytic system in a one-pot manner.
authors.affiliation: Graduate School of Pharmaceutical Sciences, Tohoku University, 6-3, Aoba, Aramaki, Aoba-ku, Sendai 980-8578, Japan. inamoto@m.tohoku.ac.jp
authors.forename: Kiyofumi
authors.initials: K
authors.lastname: Inamoto
authors.forename: Junpei
authors.initials: J
authors.lastname: Kawasaki
authors.forename: Kou
authors.initials: K
authors.lastname: Hiroya
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Kondo
authors.forename: Takayuki
authors.initials: T
authors.lastname: Doi
mesh_terms: D000577:Amides / Q000737:chemistry*; D002244:Carbon / Q000737:chemistry*; D002384:Catalysis; D006859:Hydrogen / Q000737:chemistry*; D010084:Oxidation-Reduction; D010165:Palladium / Q000737:chemistry*; D015363:Quinolones / Q000737:chemistry*
chemical_list: D000577:Amides; D015363:Quinolones; D010165:Palladium; D002244:Carbon; D006859:Hydrogen