title: 'Less is More': defining modern bioanalysis.
abstract: The 4th Open Symposium of the European Bioanalytical Forum entitled 'Less is More' was held on 16-18 November 2011 at the Hesperia Tower Hotel, Barcelona, Spain. More than 50 interesting presentations were delivered covering areas with interest for the small- and large-molecule community - biomarker validation; regulations, including an update on new and emerging guidelines and on Global harmonization; technology updates; incurred sample stability; microdosing; dried blood spots and microsampling; challenges of 'free' and 'total' macromolecule quantification; stability issues in ligand binding assays or anomalous results. In excess of 450 delegates from more than 170 institutes and companies (industry, regulators and academia) from all global regions participated in the open and stimulating discussions. This manuscript provides an overview of the highlights discussed at the meeting.
authors.forename: Jessica
authors.initials: J
authors.lastname: Dijksman
authors.forename: Philip
authors.initials: P
authors.lastname: Timmerman
authors.forename: Richard
authors.initials: R
authors.lastname: Abbott
authors.forename: Begona
authors.initials: B
authors.lastname: Barroso
authors.forename: Margarete Brudny
authors.initials: MB
authors.lastname: Kloeppel
authors.forename: Arjen
authors.initials: A
authors.lastname: Companjen
authors.forename: Michaela
authors.initials: M
authors.lastname: Golob
authors.forename: Ben
authors.initials: B
authors.lastname: Gordon
authors.forename: Christian
authors.initials: C
authors.lastname: Herling
authors.forename: Magnus
authors.initials: M
authors.lastname: Knutsson
authors.forename: Silke
authors.initials: S
authors.lastname: Luedtke
authors.forename: Birgitte Buur
authors.initials: BB
authors.lastname: Rasmussen
authors.forename: Daniela
authors.initials: D
authors.lastname: Stoellner
authors.forename: Eva
authors.initials: E
authors.lastname: Vieser
authors.forename: Graeme
authors.initials: G
authors.lastname: Young
authors.forename: Peter
authors.initials: P
authors.lastname: van Amsterdam
mesh_terms: D015415:Biomarkers / Q000032:analysis*; D002853:Chromatography, Liquid; D059788:Dried Blood Spot Testing; D017408:Guidelines as Topic; D013058:Mass Spectrometry; D010599:Pharmacokinetics
chemical_list: D015415:Biomarkers