title: Prolonged use of extracorporeal membrane oxygenation combined with prone positioning in patients with acute respiratory distress syndrome and invasive Aspergillosis.
abstract: Extracorporeal membrane oxygenation (ECMO) is increasingly being used in patients with severe acute respiratory distress syndrome. In two large cohorts of such patients, the median duration of treatment with ECMO was 9 and 10 days. We describe two patients, both with H1N1 pneumonia complicated by invasive Aspergillosis, who required ECMO support significantly longer at 45 and 52 days, but eventually made a full recovery. In both patients, prone positioning was used during ECMO treatment.
authors.affiliation: Department of Intensive Care, University Medical Centre, Utrecht, the Netherlands. l.c.otterspoor@umcutrecht.nl
authors.forename: L C
authors.initials: LC
authors.lastname: Otterspoor
authors.forename: F H
authors.initials: FH
authors.lastname: Smit
authors.forename: T J
authors.initials: TJ
authors.lastname: van Laar
authors.forename: J
authors.initials: J
authors.lastname: Kesecioglu
authors.forename: D
authors.initials: D
authors.lastname: van Dijk
mesh_terms: D001228:Aspergillosis / Q000150:complications / Q000000981:diagnostic imaging / Q000382:microbiology / Q000628:therapy*; D015199:Extracorporeal Membrane Oxygenation; D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype; D007251:Influenza, Human / Q000150:complications / Q000000981:diagnostic imaging / Q000382:microbiology / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D011024:Pneumonia, Viral / Q000150:complications / Q000000981:diagnostic imaging / Q000382:microbiology / Q000628:therapy*; D016684:Prone Position; D011859:Radiography; D012128:Respiratory Distress Syndrome / Q000150:complications / Q000000981:diagnostic imaging / Q000382:microbiology / Q000628:therapy*; D013997:Time Factors