title: Growth response and toxic effects of three antibiotics on Selenastrum capricornutum evaluated by photosynthetic rate and chlorophyll biosynthesis.
abstract: The effects of three types of antibiotics (erythromycin, ciprofloxacin and sulfamethoxazole) on the photosynthesis of freshwater algae, Selenastrum capricornutum Printz, were investigated by determining the growth rate, chloroplast pigments content, seven main precursors (including delta-aminolevulinic acid, porphobilinogen, uroporphyrinogen III, coproporphyrinogen III, protoporphyrin IX, Mg-proporphyrin IX and protochlorophyllide), and photosynthetic rate during chlorophyll biosynthesis. The antibiotics significantly decreased the growth rate, chlorophyll content, and photosynthetic rate. Erythromycin induced a decreasing effect at a concentration of 0.06 mg/L, while ciprofloxacin and sulfamethoxazole achieved the same results at concentrations higher than 1.5 mg/L. Only erythromycin significantly inhibited chlorophyll biosynthesis, which indicated that it was considerably more toxic to S. capricornutum than ciprofloxacin and sulfamethoxazole, and may pose a high potential risk to aquatic ecosystems.
authors.affiliation: Engineering Research Center of Tropical and Subtropical Aquatic Ecological Engineering, Ministry of Education, Institute ofHydrobiology, Jinan University, Guangzhou 510632, China. fleetcher2003@163.com
authors.forename: Binyang
authors.initials: B
authors.lastname: Liu
authors.forename: Weiqiu
authors.initials: W
authors.lastname: Liu
authors.forename: Xiangping
authors.initials: X
authors.lastname: Nie
authors.forename: Chao
authors.initials: C
authors.lastname: Guan
authors.forename: Yufeng
authors.initials: Y
authors.lastname: Yang
authors.forename: Zhaohui
authors.initials: Z
authors.lastname: Wang
authors.forename: Wei
authors.initials: W
authors.lastname: Liao
mesh_terms: D000900:Anti-Bacterial Agents / Q000633:toxicity*; D059001:Aquatic Organisms / Q000187:drug effects / Q000254:growth & development / Q000378:metabolism; D001426:Bacterial Proteins / Q000096:biosynthesis; D002734:Chlorophyll / Q000096:biosynthesis*; D000460:Chlorophyta / Q000187:drug effects* / Q000254:growth & development* / Q000378:metabolism; D002736:Chloroplasts / Q000187:drug effects / Q000378:metabolism; D007700:Kinetics; D010788:Photosynthesis / Q000187:drug effects*; D012306:Risk; D018675:Toxicity Tests
chemical_list: D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; D002734:Chlorophyll