title: Odontogenic tumours in children and adolescents: a collaborative study of 431 cases.
abstract: This study describes the oral and maxillofacial pathological characteristics of a series of odontogenic tumours in children and adolescents from three Brazilian reference centres. The records were reviewed for all odontogenic tumours in patients up to 18 years old based on criteria proposed by the World Health Organization (WHO) in 2005. Data concerning sex, age, skin colour and tumour location were collected and plotted. Four hundred and thirty one odontogenic tumours in children and adolescents were found, accounting for 37.5% of the total number of odontogenic tumours diagnosed. Benign tumours were predominant (99.8% of the cases), and odontoma was the most frequent type (41.4%), followed by keratocystic odontogenic tumours (25.5%) and ameloblastoma (14.6%). Odontogenic tumours were rarely detected in early childhood, and their prevalence increased with age. An almost equal distribution was observed with respect to sex and the site of the lesions. This study is the largest reported retrospective analysis describing odontogenic tumours in children and adolescents to date. The authors detected some variation in the relative frequency of odontogenic tumours compared with similar reports. Additional studies should be conducted based on the new WHO classification and predetermined age parameters to enable comparative analysis among different worldwide populations.
authors.affiliation: Oral Pathology Area, School of Dentistry, Federal University of Uberlândia, Brazil.
authors.forename: J P S
authors.initials: JP
authors.lastname: Servato
authors.forename: P E A
authors.initials: PE
authors.lastname: de Souza
authors.forename: M C R
authors.initials: MC
authors.lastname: Horta
authors.forename: D C
authors.initials: DC
authors.lastname: Ribeiro
authors.forename: M C F
authors.initials: MC
authors.lastname: de Aguiar
authors.forename: P R
authors.initials: PR
authors.lastname: de Faria
authors.forename: S V
authors.initials: SV
authors.lastname: Cardoso
authors.forename: Adriano Mota
authors.initials: AM
authors.lastname: Loyola
mesh_terms: D000293:Adolescent; D000367:Age Factors; D000564:Ameloblastoma / Q000453:epidemiology; D001938:Brazil / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008339:Mandibular Neoplasms / Q000453:epidemiology; D008441:Maxillary Neoplasms / Q000453:epidemiology; D009808:Odontogenic Tumors / Q000453:epidemiology*; D009810:Odontoma / Q000453:epidemiology; D015995:Prevalence; D012189:Retrospective Studies; D012737:Sex Factors