title: Evaluation of ultra-low dose CT in the diagnosis of pediatric-like fractures using an experimental animal study.
abstract: OBJECTIVE
  The aim of this prospective study was to evaluate the performance of ultra-low dose CT for the diagnosis of pediatric-like fractures and ascertain the lowest dose level sufficient for diagnostics.
  
  
  METHODS
  Fifty-one bones of young pig cadavers were artificially fractured and subsequently examined by using a 64 multi-detector CT with 36 various dose levels down to a dose comparable with that of X-rays. Two pediatric radiologists analysed the CT scans according to the presence or absence of a fracture, determination of the fracture type and the displacement as well as the diagnostic certainty. For each dose protocol, a success rate for the correct determination of the above-mentioned CT analyses was calculated. A success rate of at least 95% was considered sufficient for diagnostics.
  
  
  RESULTS
  All but the lowest dose levels were sufficient to identify the fracture. Only the two lowest dose levels were insufficient to detect the fracture type. All dose levels were adequate for the identification of the displacement. The lowest dose level sufficient for diagnostics was 120 kVp, 11 mAs, and pitch 1.5, with a CTDIvol of 10% of a standard dose and an effective dose three times as large as that of X-rays.
  
  
  CONCLUSIONS
  Ultra-low dose CT provides the feasibility of a significant dose reduction, still allowing sufficient diagnostics of pediatric-like fractures.
authors.affiliation: Department of Diagnostic Radiology, University Hospital Schleswig-Holstein, Kiel, Germany. joerg.d.moritz@rad.uni-kiel.de
authors.forename: Joerg D
authors.initials: JD
authors.lastname: Moritz
authors.forename: Beata
authors.initials: B
authors.lastname: Hoffmann
authors.forename: Dirk
authors.initials: D
authors.lastname: Sehr
authors.forename: Katrin
authors.initials: K
authors.lastname: Keil
authors.forename: Juliane
authors.initials: J
authors.lastname: Eggerking
authors.forename: Godo
authors.initials: G
authors.lastname: Groth
authors.forename: Amke
authors.initials: A
authors.lastname: Caliebe
authors.forename: Jens
authors.initials: J
authors.lastname: Dischinger
authors.forename: Martin
authors.initials: M
authors.lastname: Heller
authors.forename: Hendrik
authors.initials: H
authors.lastname: Bolte
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D050723:Fractures, Bone / Q000000981:diagnostic imaging*; D010372:Pediatrics / Q000379:methods; D011446:Prospective Studies; D011829:Radiation Dosage; D011857:Radiographic Image Interpretation, Computer-Assisted; D013552:Swine; D014057:Tomography, X-Ray Computed / Q000379:methods*