title: Changes in bone alkaline phosphatase and procollagen type-1 C-peptide after static and dynamic exercises.
abstract: We investigated the effects of two types of nonweight-bearing exercise on changes in bone-specific alkaline phosphatase (BAP) and procollagen type 1 C-peptide (PIP). BAP is a specific marker of bone synthesis, whereas P1P reflects synthesis of type 1 collagen in other organs as well as bone. Eight participants performed static and dynamic unilateral knee extensions. BAP and PIP were measured before, and at 1, 2, 24, 48, and 72 hr after exercise. PIP increased at 24 hr after a static knee extension exercise, whereas BAP did not change during the experimental period. We found no changes in these markers after dynamic exercise. These results imply that type I collagen synthesis in tendons increases after static exercise.
authors.affiliation: Department of Life Science (Sports Sciences) University of Tokyo, Japan. kubo@idaten.c.u-tokyo.ac.jp
authors.forename: Keitaro
authors.initials: K
authors.lastname: Kubo
authors.forename: Kazuhito
authors.initials: K
authors.lastname: Yuki
authors.forename: Toshihiro
authors.initials: T
authors.lastname: Ikebukuro
mesh_terms: D000328:Adult; D000469:Alkaline Phosphatase / Q000097:blood*; D000704:Analysis of Variance; D001842:Bone and Bones / Q000378:metabolism*; D015444:Exercise / Q000502:physiology*; D006801:Humans; D007537:Isometric Contraction; D007551:Isotonic Contraction; D007717:Knee / Q000502:physiology; D019344:Lactic Acid / Q000097:blood; D008297:Male; D018482:Muscle, Skeletal / Q000033:anatomy & histology / Q000502:physiology; D017847:Patellar Ligament / Q000378:metabolism; D010446:Peptide Fragments / Q000097:blood*; D011347:Procollagen / Q000097:blood*
chemical_list: D010446:Peptide Fragments; D011347:Procollagen; C042813:procollagen type I carboxy terminal peptide; D019344:Lactic Acid; D000469:Alkaline Phosphatase