title: Bioactive diopside (CaMgSi(2)O(6)) as a drug delivery carrier - a review.
abstract: The bone infections are the most divesting complications confronted by the physicians and patients. The antibiotic loaded bone cements, such as synthetic ceramics and natural ceramics were accepted for bone infections. The currently available bone cements were not accepted due to the lack of mechanical strength, porosity and quick degradation rate etc. The major aim of this review is to discuss about several different synthetic methods used to prepare the bioactive diopside (CaMgSi(2)O(6)) and its applications in ceramic drug delivery systems for controlled and targeted delivery. It has been reported from various research articles, diopside was mainly used for bone tissue regeneration, dentistry, orthopedics and enzyme delivery matrices with different formulations. Compared to other bioceramics diopside is preferable due to its biocompatibility and high mechanical strength.
authors.affiliation: Materials Chemistry Division, Centre for Nanomaterials, School of Advanced Sciences, VIT University, Vellore- 632 014. Tamilnadu. India. ssasikumar@vit.ac.in
authors.forename: C
authors.initials: C
authors.lastname: Saravanan
authors.forename: S
authors.initials: S
authors.lastname: Sasikumar
mesh_terms: D000818:Animals; D004337:Drug Carriers / Q000737:chemistry / Q000494:pharmacology; D006801:Humans; D008863:Microspheres; D012824:Silicic Acid / Q000737:chemistry / Q000494:pharmacology
chemical_list: D004337:Drug Carriers; D012824:Silicic Acid; C074224:diopside