title: [Hypolipidemic activity of trimethylglycine].
abstract: Hypolipidemic properties of a native trimethyl derivative of glycine, trimethylglycine (TMGl), were studied in hyperlipidemic rats and guinea pigs. The administration of TMGl to the hyperlipidemic rats and guinea pigs produced a pronounced hypolipidemic effect. A positive action of TMGl on the lipid profile of blood serum of the experimental animals was observed as manifested by a decrease in the level of cholesterol of low density lipoproteins (LDL) and an increase in the cholesterol level of high density lipoproteins (HDL).
authors.forename: N N
authors.initials: NN
authors.lastname: Kliueva
authors.forename: N M
authors.initials: NM
authors.lastname: Kalashnikova
authors.forename: I V
authors.initials: IV
authors.lastname: Okunevich
authors.forename: N S
authors.initials: NS
authors.lastname: Sapronov
mesh_terms: D000818:Animals; D000924:Anticholesteremic Agents / Q000627:therapeutic use*; D001622:Betaine / Q000627:therapeutic use*; D002784:Cholesterol / Q000097:blood; D006168:Guinea Pigs; D006949:Hyperlipidemias / Q000097:blood / Q000188:drug therapy*; D008075:Lipoproteins, HDL / Q000097:blood; D008077:Lipoproteins, LDL / Q000097:blood; D008099:Liver / Q000737:chemistry; D008297:Male; D051379:Mice; D051381:Rats
chemical_list: D000924:Anticholesteremic Agents; D008075:Lipoproteins, HDL; D008077:Lipoproteins, LDL; D001622:Betaine; D002784:Cholesterol