title: Treatments for food allergy: how close are we?
abstract: Food allergy continues to be a challenging health problem, with prevalence continuing to increase and anaphylaxis still an unpredictable possibility. While improvements in diagnosis are more accurately identifying affected individuals, treatment options remain limited. The cornerstone of treatment relies on strict avoidance of the offending allergens and education regarding management of allergic reactions. Despite vigilance in avoidance, accidental ingestions and reactions continue to occur. With recent advances in the understanding of humoral and cellular immune responses in food allergy and mechanisms of tolerance, several therapeutic strategies for food allergies are currently being investigated with the hopes of providing a cure or long-term remission from food allergy.
authors.affiliation: Division of Allergy and Immunology, Department of Pediatrics, Mount Sinai School of Medicine, One Gustave L. Levy Place, Box 1198, New York, NY 10029-6574, USA. Julie.wang@mssm.edu
authors.forename: Julie
authors.initials: J
authors.lastname: Wang
authors.forename: Hugh A
authors.initials: HA
authors.lastname: Sampson
mesh_terms: D000818:Animals; D003888:Desensitization, Immunologic / Q000379:methods; D005512:Food Hypersensitivity / Q000628:therapy*; D006376:Helminths / Q000276:immunology; D006801:Humans; D007073:Immunoglobulin E / Q000276:immunology; D015848:Interleukin-5 / Q000276:immunology; D008516:Medicine, Chinese Traditional; D019936:Probiotics / Q000627:therapeutic use; D051193:Toll-Like Receptors / Q000276:immunology
chemical_list: D015848:Interleukin-5; D051193:Toll-Like Receptors; D007073:Immunoglobulin E