title: Direct carboxamidation of indoles by palladium-catalyzed C-H activation and isocyanide insertion.
abstract: A selective C3 carboxamidation of indoles including free (N-H) ones by palladium-catalyzed sequential C-H activation-isocyanide insertion has been developed.
authors.affiliation: State Key Laboratory of Respiratory Disease, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, 190 Kaiyuan Avenue, Guangzhou 510530, China.
authors.forename: Jiangling
authors.initials: J
authors.lastname: Peng
authors.forename: Lanying
authors.initials: L
authors.lastname: Liu
authors.forename: Ziwei
authors.initials: Z
authors.lastname: Hu
authors.forename: Jinbo
authors.initials: J
authors.lastname: Huang
authors.forename: Qiang
authors.initials: Q
authors.lastname: Zhu
mesh_terms: D000085:Acetates / Q000737:chemistry; D002384:Catalysis; D003300:Copper / Q000737:chemistry; D003486:Cyanides / Q000737:chemistry*; D007211:Indoles / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*
chemical_list: D000085:Acetates; D003486:Cyanides; D007211:Indoles; D010165:Palladium; D003300:Copper