title: Oxazolidinone-promoted, torquoselective Nazarov cyclizations.
abstract: Oxazolidinones are powerful promoters of the Nazarov reaction, enabling the cyclization of conventionally resistant substrates to be achieved under mild conditions. They exert excellent regio- and torquoselective control in both the conventional Nazarov reaction giving cyclopentenones and in the "interrupted" Nazarov reaction, giving more highly substituted multistereocenter containing products.
authors.affiliation: Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, Victoria 3052, Australia.
authors.forename: Daniel J
authors.initials: DJ
authors.lastname: Kerr
authors.forename: Michael
authors.initials: M
authors.lastname: Miletic
authors.forename: Jason H
authors.initials: JH
authors.lastname: Chaplin
authors.forename: Jonathan M
authors.initials: JM
authors.lastname: White
authors.forename: Bernard L
authors.initials: BL
authors.lastname: Flynn
mesh_terms: D002384:Catalysis; D003500:Cyclization; D003517:Cyclopentanes / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D023303:Oxazolidinones / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D003517:Cyclopentanes; D023303:Oxazolidinones; C013905:cyclopentenone