title: Comparison of cardiac positron emission tomography perfusion defects during stress induced by hemodialysis versus adenosine.
abstract: The cardiac stress imposed by hemodialysis may differ from that induced by pharmacologic agents used for myocardial perfusion imaging-based stress testing. With repetitive intradialytic [(13)N]ammonia positron emission tomography, we showed that standard hemodialysis had an acute adverse effect on cardiac perfusion and left ventricular function that was not detected by standard diagnostic adenosine stress testing.
authors.affiliation: Department of Internal Medicine, Division of Nephrology, University Medical Center Groningen, Groningen, the Netherlands.
authors.forename: Solmaz
authors.initials: S
authors.lastname: Assa
authors.forename: Judith J
authors.initials: JJ
authors.lastname: Dasselaar
authors.forename: Riemer H J A
authors.initials: RH
authors.lastname: Slart
authors.forename: Paul E
authors.initials: PE
authors.lastname: de Jong
authors.forename: Adriaan A
authors.initials: AA
authors.lastname: Voors
authors.forename: René A
authors.initials: RA
authors.lastname: Tio
authors.forename: Casper F M
authors.initials: CF
authors.lastname: Franssen
mesh_terms: D000241:Adenosine; D005080:Exercise Test; D005500:Follow-Up Studies; D006801:Humans; D006977:Hypertension, Renal / Q000150:complications / Q000175:diagnosis; D007676:Kidney Failure, Chronic / Q000209:etiology / Q000503:physiopathology / Q000628:therapy; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000000981:diagnostic imaging / Q000209:etiology* / Q000503:physiopathology; D055414:Myocardial Perfusion Imaging / Q000009:adverse effects / Q000379:methods*; D049268:Positron-Emission Tomography / Q000009:adverse effects / Q000379:methods*; D019275:Radiopharmaceuticals; D006435:Renal Dialysis / Q000009:adverse effects* / Q000379:methods; D018570:Risk Assessment; D018487:Ventricular Dysfunction, Left / Q000000981:diagnostic imaging / Q000209:etiology* / Q000503:physiopathology
chemical_list: D019275:Radiopharmaceuticals; D000241:Adenosine