title: Relationship between left ventricular ejection fraction and mitral annular displacement derived by speckle tracking echocardiography in patients with different heart diseases.
abstract: BACKGROUND
  Speckle tracking echocardiography (STE)-derived mitral annular displacement (MAD) utilizes the speckle tracking technique to measure strain vectors, which provides accurate estimates of left ventricular ejection fraction (LVEF). Here, we investigated a link between STE-derived MAD and LVEF in patients with different heart diseases and evaluated its clinical usefulness.
  
  
  METHODS
  This study included 266 outpatients and 84 controls. Of the study patients, 52 patients had ischemic heart disease (IHD), 37 patients had dilated cardiomyopathy (DCM), 34 patients had hypertrophic cardiomyopathy (HCM), 74 patients had valvular heart disease (VHD), and 69 patients had hypertensive heart disease (HHD). STE continuously tracked annular motion throughout the cardiac cycle in the apical 4- and 2-chamber views.
  
  
  RESULTS
  In all participants, the curvilinear relationship was found between STE-derived MAD and LVEF (R(2)=0.642). The strong correlation between STE-derived MAD and LVEF was also found in the patients with IHD (R(2)=0.733, p=0.001) and in those with DCM (R(2)=0.614, p=0.008). However, such a correlation was not found in the patients with HCM, VHD, or HHD.
  
  
  CONCLUSIONS
  The specificity in the correlation between STE-derived MAD and LVEF was found in patients with each heart disease, which should be taken into account when assessing these parameters.
authors.affiliation: Division of Cardiology, Department of Internal Medicine, St. Marianna University School of Medicine, Kawasaki, Kanagawa, Japan. kengo@marianna-u.ac.jp
authors.forename: Kengo
authors.initials: K
authors.lastname: Suzuki
authors.forename: Yoshihiro J
authors.initials: YJ
authors.lastname: Akashi
authors.forename: Kei
authors.initials: K
authors.lastname: Mizukoshi
authors.forename: Seisyou
authors.initials: S
authors.lastname: Kou
authors.forename: Manabu
authors.initials: M
authors.lastname: Takai
authors.forename: Masaki
authors.initials: M
authors.lastname: Izumo
authors.forename: Akio
authors.initials: A
authors.lastname: Hayashi
authors.forename: Eiji
authors.initials: E
authors.lastname: Ohtaki
authors.forename: Sachihiko
authors.initials: S
authors.lastname: Nobuoka
authors.forename: Fumihiko
authors.initials: F
authors.lastname: Miyake
mesh_terms: D000368:Aged; D004452:Echocardiography / Q000379:methods*; D005260:Female; D006331:Heart Diseases / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008943:Mitral Valve / Q000503:physiopathology*; D013318:Stroke Volume / Q000502:physiology*