title: Hypogonadism secondary to hyperprolactinaemia: successful treatment but adverse consequences.
abstract: It is accepted that care must be taken in initiating testosterone replacement in hypogonadal individuals with historically low androgen levels. However less is reported about the influence of restoration of normal endogenous testosterone production on behaviour.Here we report how the adverse sequelae of successful treatment of hypogonadism secondary to hyperprolactinaemia, manifesting as irritability and low threshold to aggression, were managed through a joint approach between psychiatrist and physician.
authors.affiliation: Leighton Hospital, Crewe, UK, Cheshire.
authors.forename: R P
authors.initials: RP
authors.lastname: Narayanan
authors.forename: S
authors.initials: S
authors.lastname: Bujawansa
authors.forename: Z
authors.initials: Z
authors.lastname: Qureshi
authors.forename: M
authors.initials: M
authors.lastname: Rimmer
authors.forename: A
authors.initials: A
authors.lastname: Heald
mesh_terms: D000328:Adult; D000634:Aminoquinolines / Q000009:adverse effects / Q000627:therapeutic use*; D001521:Behavior Therapy / Q000379:methods; D018491:Dopamine Agonists / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D006966:Hyperprolactinemia / Q000188:drug therapy / Q000473:pathology*; D007006:Hypogonadism / Q000097:blood* / Q000188:drug therapy; D008297:Male; D010911:Pituitary Neoplasms / Q000097:blood / Q000188:drug therapy / Q000473:pathology*
chemical_list: D000634:Aminoquinolines; D018491:Dopamine Agonists; C046650:quinagolide