title: Diacarperoxide S, new norterpene cyclic peroxide from the sponge Diacarnus megaspinorhabdosa.
abstract: Re-investigation of the methanolic extract of the sponge Diacarnus megaspinorhabdosa afforded one new norsesterpene cyclic peroxide diacarperoxide S (2), in addition to two known compounds sigmosceptrellin B (1) and nebularine (3). The structures of the isolated compounds were established on the basis of one and two dimensional NMR spectroscopic studies (1H, 13C, DEPT, COSY, HMQC, HMBC, and ROESY) as well as on mass spectral analysis. The isolated compounds were evaluated for their cytotoxic as well as antimicrobial activities.
authors.affiliation: Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut 71526, Egypt. sabrins2000@yahoo.com
authors.forename: Sabrin R M
authors.initials: SR
authors.lastname: Ibrahim
mesh_terms: D000818:Animals; D001419:Bacteria / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D010545:Peroxides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D011161:Porifera / Q000378:metabolism*; D013729:Terpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: D010545:Peroxides; D013729:Terpenes; C571769:diacarperoxide S