title: [Cell-based strategies: novel perspectives for cancer therapy].
abstract: Cellular therapies represent an emerging field in oncology. Several studies support the efficacy of cell-based immunotherapies for different solid tumors. Recent approaches, however, have been optimized in using adult stem cells, genetically modified to produce cytotoxic molecules for fighting cancer. In this review, we focused major preclinical and clinical results in this fascinating field of cell-based strategies against cancer.
authors.affiliation: Dipartimento di Scienze Biomediche e Oncologia Umana, Sezione di Oncologia Medica, Università Aldo Moro, Bari.
authors.forename: Valeria
authors.initials: V
authors.lastname: Simone
authors.forename: Sabino
authors.initials: S
authors.lastname: Ciavarella
authors.forename: Stella
authors.initials: S
authors.lastname: D'Oronzo
authors.forename: Franco
authors.initials: F
authors.lastname: Silvestris
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D003713:Dendritic Cells / Q000276:immunology / Q000637:transplantation; D019317:Evidence-Based Medicine; D006801:Humans; D007167:Immunotherapy / Q000379:methods; D007376:Interleukin-2 / Q000627:therapeutic use*; D015979:Killer Cells, Lymphokine-Activated; D045164:Mesenchymal Stem Cell Transplantation; D009369:Neoplasms / Q000188:drug therapy* / Q000276:immunology / Q000601:surgery*; D016896:Treatment Outcome
chemical_list: D000970:Antineoplastic Agents; D007376:Interleukin-2