title: A pilot study of silver-loaded cellulose fabric with incorporated seaweed for the treatment of atopic dermatitis.
abstract: Because clothing has the longest and most direct contact with human skin, it is important to carefully choose suitable fabrics for atopic patients who have disrupted skin. To evaluate the clinical effectiveness and biophysical properties of a newly developed silver-loaded cellulose fabric with incorporated seaweed, we enrolled 12 subjects with mild to moderate atopic dermatitis into a clinical control study. The subjects wore a two-piece garment (top and leggings), each piece of which was divided into two parts: one side was made of SkinDoctor(®)  fabric, and the other of 100% cotton. Treatment efficacy was measured with the modified SCORing Atopic Dermatitis (mSCORAD) index, transepidermal water loss (TEWL) and the patients' subjective impressions. All three of these measures had significantly better scores on the side covered with SkinDoctor. These results suggest that SkinDoctor is a beneficial fabric that can improve the comfort of patients with AD.
authors.affiliation: Department of Dermatology, Chung-Ang University College of Medicine, Seoul, South Korea.
authors.forename: K Y
authors.initials: KY
authors.lastname: Park
authors.forename: W S
authors.initials: WS
authors.lastname: Jang
authors.forename: G W
authors.initials: GW
authors.lastname: Yang
authors.forename: Y H
authors.initials: YH
authors.lastname: Rho
authors.forename: B J
authors.initials: BJ
authors.lastname: Kim
authors.forename: S K
authors.initials: SK
authors.lastname: Mun
authors.forename: C W
authors.initials: CW
authors.lastname: Kim
authors.forename: M N
authors.initials: MN
authors.lastname: Kim
mesh_terms: D000293:Adolescent; D000328:Adult; D002482:Cellulose / Q000627:therapeutic use*; D002648:Child; D003020:Clothing; D032561:Cotton Fiber; D003876:Dermatitis, Atopic / Q000188:drug therapy* / Q000503:physiopathology; D004338:Drug Combinations; D005260:Female; D006801:Humans; D008297:Male; D017060:Patient Satisfaction; D010865:Pilot Projects; D012624:Seaweed; D012720:Severity of Illness Index; D012834:Silver / Q000627:therapeutic use*; D014025:Titanium / Q000627:therapeutic use; D014870:Water Loss, Insensible / Q000502:physiology; D055815:Young Adult
chemical_list: D004338:Drug Combinations; C009495:titanium dioxide; D012834:Silver; D002482:Cellulose; D014025:Titanium