title: Interrelation of cell apoptosis and proliferation in the thymus during its involution.
abstract: In people over 60 years, thymocytes contain proliferation protein Ki67 and proapoptotic protein P53. During aging, apoptosis of thymus cell prevails over proliferation, though thymocytes retain proliferative capacity even in long-livers.
authors.affiliation: St. Petersburg Institute of Bioregulation and Gerontology, Northwestern Division of Russian Academy of Medical Sciences, Russia. miayy@yandex.ru
authors.forename: N S
authors.initials: NS
authors.lastname: Linkova
authors.forename: V O
authors.initials: VO
authors.lastname: Polyakova
authors.forename: I M
authors.initials: IM
authors.lastname: Kvetnoy
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D017209:Apoptosis; D049109:Cell Proliferation; D006801:Humans; D019394:Ki-67 Antigen / Q000378:metabolism; D008875:Middle Aged; D013950:Thymus Gland / Q000166:cytology* / Q000378:metabolism; D016159:Tumor Suppressor Protein p53 / Q000378:metabolism
chemical_list: D019394:Ki-67 Antigen; D016159:Tumor Suppressor Protein p53