title: Haptoglobin genotype and its role in diabetic cardiovascular disease.
abstract: Over the past decade, several longitudinal epidemiological studies have brought attention to the haptoglobin genotype and its importance in determining diabetic vascular disease risk. This manuscript presents an overview of the biology of the haptoglobin genotype and reviews the literature concerning its role in the development of cardiovascular disease among individuals with diabetes mellitus.
authors.affiliation: Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA 15213, USA. costacout@edc.pitt.edu
authors.forename: Tina
authors.initials: T
authors.lastname: Costacou
authors.forename: Andrew P
authors.initials: AP
authors.lastname: Levy
mesh_terms: D000818:Animals; D002318:Cardiovascular Diseases / Q000453:epidemiology / Q000235:genetics* / Q000276:immunology; D048909:Diabetes Complications / Q000453:epidemiology / Q000235:genetics* / Q000276:immunology; D003920:Diabetes Mellitus / Q000453:epidemiology / Q000235:genetics* / Q000276:immunology; D003925:Diabetic Angiopathies / Q000453:epidemiology / Q000235:genetics* / Q000276:immunology; D020022:Genetic Predisposition to Disease; D006242:Haptoglobins / Q000737:chemistry / Q000235:genetics* / Q000378:metabolism; D006801:Humans; D015994:Incidence; D010641:Phenotype; D011110:Polymorphism, Genetic; D011379:Prognosis; D011487:Protein Conformation; D018570:Risk Assessment; D012307:Risk Factors; D013329:Structure-Activity Relationship
chemical_list: C485359:HP protein, human; D006242:Haptoglobins