title: [Biological effect of fullerene (C60) to lung by inhalation or instillation].
abstract: Fullerene (C60) is a newly generated nanoparticle that has a soccer-ball structure with 60 carbon atoms. Fullerenes are expected to have a multitude of uses, for example as energy device materials or information technology materials. The biological effects of nanoparticles are now being discussed, and there are ongoing animal studies using various nanoparticles. Here we review some reports about the toxicity of C60, and in addition we present the results of our 2-year follow up studies of instillation and inhalation of C60 via the trachea.
authors.affiliation: Department of Work Systems and Health, Institute ofl Industrial Ecological Sciences, University of Occupational and Environmental Health, Japan.
authors.forename: Akira
authors.initials: A
authors.lastname: Ogami
authors.forename: Yasuo
authors.initials: Y
authors.lastname: Morimoto
authors.forename: Toshihiko
authors.initials: T
authors.lastname: Myojo
authors.forename: Takako
authors.initials: T
authors.lastname: Oyabu
mesh_terms: D000280:Administration, Inhalation; D000818:Animals; D037741:Fullerenes / Q000008:administration & dosage / Q000633:toxicity*; D008168:Lung / Q000187:drug effects* / Q000473:pathology; D051381:Rats
chemical_list: D037741:Fullerenes