title: A study on inorganic elements in psammomas from ovarian & thyroid cancer.
abstract: OBJECTIVE
  Concentric lamellar calcifications known as psammoma bodies (PB) are found in benign and malignant tumours. Whether or not the inorganic element concentrations in psammomas are similar to serous adenocarcinoma of the ovary and thyroid papillary cancer tissues has not yet been ascertained. We undertook this retrospective study to establish if there is any difference in the concentrations of inorganic ions found in psammomas in serous adenocarcinoma of the ovary, and those found in thyroid papillary cancer tissue.
  
  
  METHODS
  PB samples from patients with adenocarcinoma of the ovary (n = 10) and with thyroid papillary cancer (n = 10) were analyzed through inductively-coupled plasma spectroscopy (ICP).
  
  
  RESULTS
  There were no significant differences in the concentrations of inorganic elements in PB from thyroid papillary cancer than in those PB from ovarian cancer.
  
  
  CONCLUSIONS
  Differences in the concentrations of inorganic elements may be due to the variation in environmental pollution. Our study had limitation of small sample size. Our results suggest that some inorganic elements can participate in the origin of psammoma bodies.
authors.affiliation: Biological & Medical Sciences Research Center, The School of Medicine & Surgery, UABJO, Oaxaca, Mexico. perezcampos@prodigy.net.mx
authors.forename: Pedro S
authors.initials: PS
authors.lastname: Olivera Merlin
authors.forename: Paulina del C
authors.initials: Pdel C
authors.lastname: Leyva Bohorquez
authors.forename: Ruth
authors.initials: R
authors.lastname: Martínez-Cruz
authors.forename: Socorro
authors.initials: S
authors.lastname: Pina Canseco
authors.forename: Pedro
authors.initials: P
authors.lastname: Hernandez
authors.forename: Margarito
authors.initials: M
authors.lastname: Martínez-Cruz
authors.forename: Manuel
authors.initials: M
authors.lastname: Sánchez Rubio
authors.forename: Lucía
authors.initials: L
authors.lastname: Martínez Martínez
authors.forename: Eduardo
authors.initials: E
authors.lastname: Pérez-Campos
mesh_terms: D000230:Adenocarcinoma / Q000737:chemistry; D002277:Carcinoma; D002291:Carcinoma, Papillary; D005260:Female; D006801:Humans; D007287:Inorganic Chemicals / Q000032:analysis*; D007477:Ions / Q000032:analysis*; D010051:Ovarian Neoplasms / Q000737:chemistry*; D000077273:Thyroid Cancer, Papillary; D013964:Thyroid Neoplasms / Q000737:chemistry*
chemical_list: D007287:Inorganic Chemicals; D007477:Ions