title: Role of antibodies to neuronal α7-acetylcholine receptors in myasthenia.
abstract: The role of antibodies to a fragment of neuronal acetylcholine receptor was studied by EIA in patients with myasthenia. Antibody levels were significantly higher in patients with generalized myasthenia. Enzyme immunoassay of antibodies by the reaction with acetylcholine receptor fragment can serve as an additional method for studies of autoimmune myasthenia pathogenesis.
authors.affiliation: Institute of General Pathology and Pathophysiology, Russian Academy of Medical Sciences, Moscow, Russia.
authors.forename: V B
authors.initials: VB
authors.lastname: Lantzova
authors.forename: E K
authors.initials: EK
authors.lastname: Sepp
authors.forename: A S
authors.initials: AS
authors.lastname: Kozlovskii
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001323:Autoantibodies / Q000097:blood* / Q000276:immunology*; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D008297:Male; D008875:Middle Aged; D009132:Muscles / Q000378:metabolism / Q000473:pathology; D009157:Myasthenia Gravis / Q000276:immunology* / Q000473:pathology; D009474:Neurons / Q000378:metabolism; D011978:Receptors, Nicotinic / Q000276:immunology*; D055815:Young Adult; D064569:alpha7 Nicotinic Acetylcholine Receptor
chemical_list: D001323:Autoantibodies; C579167:Chrna7 protein, human; D011978:Receptors, Nicotinic; D064569:alpha7 Nicotinic Acetylcholine Receptor