title: Disintegrating brain networks: from syndromes to molecular nexopathies.
abstract: In this issue of Neuron, Raj et al. (2012) and Zhou et al. (2012) use graph theory to suggest that neurodegenerative diseases spread diffusively via intrinsic brain networks. These studies provide a powerful model for understanding and predicting disease-specific profiles of neurodegeneration.
authors.affiliation: Dementia Research Centre, Department of Neurodegenerative Disease, University College London Institute of Neurology, London WC1N 3BG, UK. jason.warren@ucl.ac.uk
authors.forename: Jason D
authors.initials: JD
authors.lastname: Warren
authors.forename: Jonathan D
authors.initials: JD
authors.lastname: Rohrer
authors.forename: John
authors.initials: J
authors.lastname: Hardy
mesh_terms: D001921:Brain / Q000098:blood supply* / Q000473:pathology*; D001931:Brain Mapping; D003704:Dementia / Q000473:pathology* / Q000503:physiopathology*; D018450:Disease Progression; D005260:Female; D006801:Humans; D008297:Male; D008959:Models, Neurological; D019636:Neurodegenerative Diseases / Q000175:diagnosis*