title: The science behind percutaneous hemodynamic support: a review and comparison of support strategies.
abstract: Patients in a variety of cardiovascular disease states may benefit from temporary percutaneous cardiac support, including those in acute decompensated heart failure, fulminant myocarditis, acute myocardial infarction with or without cardiogenic shock and those undergoing high-risk percutaneous coronary intervention. The ideal percutaneous cardiac support device is safe, easy to use and versatile enough to meet the needs of various clinical situations and patient cohorts. In addition, it should provide maximal hemodynamic support and protection against myocardial ischemia. With these goals in mind, the scientific principles that govern hemodynamic effectiveness and myocardial protection as they pertain to acute support devices are reviewed.
authors.affiliation: Division of Cardiology, Columbia University School of Medicine, New York, New York, USA. db59@columbia.edu
authors.forename: Daniel
authors.initials: D
authors.lastname: Burkhoff
authors.forename: Srihari S
authors.initials: SS
authors.lastname: Naidu
mesh_terms: D000818:Animals; D001243:Assisted Circulation / Q000009:adverse effects / Q000295:instrumentation*; D002318:Cardiovascular Diseases / Q000503:physiopathology / Q000628:therapy*; D006353:Heart-Assist Devices / Q000009:adverse effects; D006439:Hemodynamics; D006801:Humans; D008955:Models, Cardiovascular; D011474:Prosthesis Design; D016896:Treatment Outcome; D016277:Ventricular Function, Left