title: False-negative hepatitis B virus (HBV) surface antigen in a vaccinated dialysis patient with a high level of HBV DNA in the United States.
abstract: Screening with hepatitis B surface antigen (HBsAg) is highly recommended for at-risk individuals. Mutations in the HBsAg can result in an inability to detect the virus during routine screening. We describe a hemodialysis patient found to have high levels of hepatitis B virus (HBV) DNA and HBV antibody but negative HBsAg on two routine assays.
authors.affiliation: Medicine, Johns Hopkins Medical Center, Baltimore, Maryland, USA.
authors.forename: Matthew C
authors.initials: MC
authors.lastname: Foy
authors.forename: Chloe L
authors.initials: CL
authors.lastname: Thio
authors.forename: Hyon S
authors.initials: HS
authors.lastname: Hwang
authors.forename: Melissa
authors.initials: M
authors.lastname: Saulynas
authors.forename: James P
authors.initials: JP
authors.lastname: Hamilton
authors.forename: Derek M
authors.initials: DM
authors.lastname: Fine
authors.forename: Mohamed G
authors.initials: MG
authors.lastname: Atta
mesh_terms: D004279:DNA, Viral / Q000097:blood*; D005188:False Negative Reactions; D005260:Female; D006509:Hepatitis B / Q000175:diagnosis* / Q000821:virology*; D006510:Hepatitis B Antibodies / Q000097:blood; D006514:Hepatitis B Surface Antigens / Q000097:blood*; D006515:Hepatitis B virus / Q000302:isolation & purification*; D006801:Humans; D008875:Middle Aged; D006435:Renal Dialysis / Q000009:adverse effects*; D014481:United States
chemical_list: D004279:DNA, Viral; D006510:Hepatitis B Antibodies; D006514:Hepatitis B Surface Antigens