title: [Indirect comparisons in drug assessment reports on the GENESIS group (SEFH) webpage].
abstract: OBJECTIVE
  Quantify use of indirect comparisons (IC) in drug evaluation reports published on the GENESIS Group web page for new drug assessment, standardisation, and drug selection research.
  
  
  METHODS
  Retrospective study of drug reports written between 2008 and 2009.
  
  
  METHODS
  presence of an active comparator and details from any direct and indirect comparative studies included.
  
  
  RESULTS
  An active comparator was present in 95% of the 337 analysed reports; 50% included a direct comparative study vs comparator. In 114 reports (34%), an IC was used; 69% of the ICs were made by the report author. Most ICs were narrative and none were adjusted. An IC could have been made in an additional 16% of the cases and possibly in 24% more.
  
  
  CONCLUSIONS
  Most evaluated drugs have an active comparator but studies comparing them directly are not as common. ICs could be included in more reports along with quality control criteria.
authors.affiliation: Servicio de Farmacia, Clínica Universidad de Navarra, Pamplona, España. aortega@unav.es
authors.forename: A
authors.initials: A
authors.lastname: Ortega Eslava
authors.forename: M D
authors.initials: MD
authors.lastname: Fraga Fuentes
authors.forename: F
authors.initials: F
authors.lastname: Puigventós Latorre
authors.forename: B
authors.initials: B
authors.lastname: Santos-Ramos
authors.forename: A
authors.initials: A
authors.lastname: Clopés Estela
authors.forename: M
authors.initials: M
authors.lastname: Vilanova Boltó
mesh_terms: D004341:Drug Evaluation; D006801:Humans; D020407:Internet; D012107:Research Design; D012189:Retrospective Studies; D016896:Treatment Outcome