title: Foreskin analysis of circumcised boys with and without previous topical corticosteroid.
abstract: Problems with the foreskin are common reasons for pediatric surgery consultations. We collected the foreskin of 40 patients for 2 years and these samples were divided into groups with and without previous topical corticosteroid. We carried out histochemical hematoxylin & eosin and Picrosirius analyses of the foreskin. Collagen fibers and inflammatory infiltrate was higher in samples from patients who had complications related to phimosis. Fibrosis was higher in patients who used topical corticosteroid. A histopathologic study of the foreskin may provide an additional analysis of patients undergoing circumcision and it can also improve the accuracy of surgical indication.
authors.affiliation: Departments of Pediatric Surgery and Surgery, Triângulo Mineiro Federal University, Uberaba, Brazil.
authors.forename: Luis Gustavo
authors.initials: LG
authors.lastname: Sabino Borges
authors.forename: Adriana Cartafina
authors.initials: AC
authors.lastname: Perez-Bóscollo
authors.forename: Laura Penna
authors.initials: LP
authors.lastname: Rocha
authors.forename: Renata Calciolari Rossi
authors.initials: RC
authors.lastname: Silva
authors.forename: Camila Souza de Oliveira
authors.initials: CS
authors.lastname: Guimarães
authors.forename: Eumenia Costa da Cunha
authors.initials: EC
authors.lastname: Castro
authors.forename: Rosana Rosa Miranda
authors.initials: RR
authors.lastname: Corrêa
mesh_terms: D000287:Administration, Topical; D000293:Adolescent; D001623:Betamethasone / Q000008:administration & dosage*; D002648:Child; D002675:Child, Preschool; D002944:Circumcision, Male; D003094:Collagen / Q000378:metabolism; D005355:Fibrosis / Q000139:chemically induced / Q000473:pathology; D052816:Foreskin / Q000378:metabolism / Q000473:pathology*; D005938:Glucocorticoids / Q000008:administration & dosage*; D006801:Humans; D008297:Male; D010688:Phimosis / Q000188:drug therapy* / Q000209:etiology / Q000601:surgery; D012189:Retrospective Studies
chemical_list: D005938:Glucocorticoids; D003094:Collagen; D001623:Betamethasone