title: Effect of oral supplementation of the probiotic capsule UB-01BV in the treatment of patients with bacterial vaginosis.
abstract: Bacterial vaginosis (BV) is a common condition affecting millions of women annually and is characterised by a reduction in native lactobacilli. Antimicrobial therapy used to cure the disease is often found to be ineffective. We postulate that the potential probiotic capsule UB-01BV might be efficient in the treatment of BV. In the present study, 30 Indian women diagnosed with BV presenting symptoms such as white discharge, pH greater than 4.7, increased discharge, odour, colour of discharge and pruritus were included. All subjects were assigned to receive two potential probiotic capsules UB-01BV a day for 7 days. At the end of the treatment all subjects showed significant (P<0.001) positive response as revealed by a reduction in vaginosis symptoms. Therefore, the results of the present study provide the first preliminary evidence that the potential probiotic capsule UB-01BV can exert a significant reduction in vaginal infection.
authors.affiliation: Centre for Research & Development, Unique Biotech Limited, SP Biotech Park, Phase-II, Plot-2, Shameerpet, Hyderabad 500078, AP, India. sudha.ratna@gmail.com
authors.forename: M Ratna
authors.initials: MR
authors.lastname: Sudha
authors.forename: A K
authors.initials: AK
authors.lastname: Maurya
mesh_terms: D000284:Administration, Oral; D002214:Capsules / Q000008:administration & dosage / Q000009:adverse effects; D004032:Diet / Q000379:methods*; D005260:Female; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007194:India; D007778:Lactobacillus / Q000502:physiology*; D009812:Odorants / Q000517:prevention & control; D019936:Probiotics / Q000008:administration & dosage* / Q000009:adverse effects; D011537:Pruritus / Q000628:therapy; D016896:Treatment Outcome; D019522:Vaginal Discharge / Q000473:pathology / Q000517:prevention & control; D016585:Vaginosis, Bacterial / Q000473:pathology / Q000628:therapy*
chemical_list: D002214:Capsules