title: Outcome of repeat trabeculectomies.
abstract: BACKGROUND
  To determine the success of repeat trabeculectomy augmented with mitomycin C in a cohort of patients who had undergone previously failed trabeculectomy surgery.
  
  
  METHODS
  A consecutive cohort series of patients.
  
  
  METHODS
  Fifty patients undergoing augmented trabeculectomy surgery following a previously failed trabeculectomy and at least 12 months' follow up.
  
  
  METHODS
  All patients had demographic and clinical data collected at the time of surgery and at all subsequent follow-up visits.
  
  
  METHODS
  Visual field progression, loss of visual acuity, intraocular pressure (IOP) control.
  
  
  RESULTS
  The mean follow up was 36.7 months. Forty-one patients (82%) achieved an IOP ≤21 mmHg (with ≥20% reduction of preoperative IOP) and ≥6 mmHg on no additional glaucoma treatment at 12 months' follow up. Forty-four patients (88%) achieved a qualified success with the same criteria at 1 year. The median logMAR acuity preoperative was unchanged after surgery; however, 11 patients (22%) lost ≥2 Snellen lines during follow up. There was no significant change in mean deviation during the follow-up period.
  
  
  CONCLUSIONS
  Repeating trabeculectomy augmented with mitomycin C is an effective method of controlling IOP and preventing further visual deterioration in the majority of patients treated. However, visual loss was seen in a significant proportion of patients.
authors.affiliation: Department of Ophthalmology and Visual Sciences, Nottingham University Hospital, Nottingham.
authors.forename: Carpi
authors.initials: C
authors.lastname: Olali
authors.forename: Alan P
authors.initials: AP
authors.lastname: Rotchford
authors.forename: Anthony J
authors.initials: AJ
authors.lastname: King
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000477:Alkylating Agents / Q000008:administration & dosage; D002648:Child; D005260:Female; D005901:Glaucoma / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology; D008297:Male; D008875:Middle Aged; D016685:Mitomycin / Q000008:administration & dosage; D011183:Postoperative Complications; D012086:Reoperation; D014130:Trabeculectomy; D016896:Treatment Outcome; D014792:Visual Acuity / Q000502:physiology; D014794:Visual Fields / Q000502:physiology
chemical_list: D000477:Alkylating Agents; D016685:Mitomycin