title: Setting up a bioreactor for recombinant protein production in yeast.
abstract: Scale-up from shake flasks to bioreactors allows for the more reproducible, high-yielding production of recombinant proteins in yeast. The ability to control growth conditions through real-time monitoring facilitates further optimization of the process. The setup of a 3-L stirred-tank bioreactor for such an application is described.
authors.affiliation: School of Life and Health Sciences, Aston University, Birmingham, UK. s.j.routledge@aston.ac.uk
authors.forename: Sarah J
authors.initials: SJ
authors.lastname: Routledge
authors.forename: Michelle
authors.initials: M
authors.lastname: Clare
mesh_terms: D019149:Bioreactors / Q000382:microbiology*; D010843:Pichia / Q000235:genetics / Q000254:growth & development / Q000378:metabolism; D011994:Recombinant Proteins / Q000235:genetics / Q000378:metabolism*; D015003:Yeasts / Q000235:genetics / Q000254:growth & development / Q000378:metabolism*
chemical_list: D011994:Recombinant Proteins