title: Kinetics and mechanism of organocatalytic aza-Michael additions: direct observation of enamine intermediates.
abstract: The imidazoles 1a-g add to the CC-double bond of the iminium ion 2 with rate constants as predicted by the equation log k = s(N)(N + E). Unfavourable proton shifts from the imidazolium unit to the enamine fragment in the adduct 3 account for the failure of imidazoles to take part in iminium-activated aza-Michael additions to enals.
authors.affiliation: Department Chemie, Ludwig-Maximilians-Universität München, Butenandtstr. 5-13 (Haus F), 81377 München, Germany.
authors.forename: Sami
authors.initials: S
authors.lastname: Lakhdar
authors.forename: Mahiuddin
authors.initials: M
authors.lastname: Baidya
authors.forename: Herbert
authors.initials: H
authors.lastname: Mayr