title: Hierarchically driven IrO2 nanowire electrocatalysts for direct sensing of biomolecules.
abstract: Applying nanoscale device fabrications toward biomolecules, ultra sensitive, selective, robust, and reliable chemical or biological microsensors have been one of the most fascinating research directions in our life science. Here we introduce hierarchically driven iridium dioxide (IrO(2)) nanowires directly on a platinum (Pt) microwire, which allows a simple fabrication of the amperometric sensor and shows a favorable electronic property desired for sensing of hydrogen peroxide (H(2)O(2)) and dihydronicotinamide adenine dinucleotide (NADH) without the aid of enzymes. This rational engineering of a nanoscale architecture based on the direct formation of the hierarchical 1-dimensional (1-D) nanostructures on an electrode can offer a useful platform for high-performance electrochemical biosensors, enabling the efficient, ultrasensitive detection of biologically important molecules.
authors.affiliation: Department of Chemistry & Nano Science, Ewha Womans University, Seoul 120-750, Korea.
authors.forename: Jun Ho
authors.initials: JH
authors.lastname: Shim
authors.forename: Yumin
authors.initials: Y
authors.lastname: Lee
authors.forename: Minkyung
authors.initials: M
authors.lastname: Kang
authors.forename: Jaeyeon
authors.initials: J
authors.lastname: Lee
authors.forename: Jeong Min
authors.initials: JM
authors.lastname: Baik
authors.forename: Youngmi
authors.initials: Y
authors.lastname: Lee
authors.forename: Chongmok
authors.initials: C
authors.lastname: Lee
authors.forename: Myung Hwa
authors.initials: MH
authors.lastname: Kim
mesh_terms: D015374:Biosensing Techniques; D002384:Catalysis; D004563:Electrochemistry; D006861:Hydrogen Peroxide / Q000032:analysis*; D007495:Iridium / Q000737:chemistry*; D057230:Limit of Detection; D009243:NAD / Q000032:analysis*; D053770:Nanowires / Q000737:chemistry*; D010984:Platinum / Q000737:chemistry
chemical_list: D009243:NAD; C044458:iridium oxide; D007495:Iridium; D010984:Platinum; D006861:Hydrogen Peroxide