title: Giant malignant meningioma invading the calvarial bone and scalp.
abstract: Meningiomas are common and mostly benign intracranial tumors, but malignant meningioma is a rare subtype with high recurrence rate and poor prognosis. Also, most meningiomas grow intracranially, and extracranial growth of meningiomas has rarely been reported. We present here a rare case of a giant malignant meningioma with multiple recurrences. The patient was a 73-year-old woman who was evaluated to have a malignant meningioma of the frontal part of the skull 3 years before being admitted to our hospital and received surgical treatment. The tumor recurred 3 years after the first surgery and was classified as a giant meningioma on admission to our hospital. We performed total resection of the giant meningioma and reconstructed the defect with artificial dura, skull, and a local rotating flap. The patient recovered and lived well for 1 year. However, 15 months after surgery, the patient died of the recurrent tumor after refusing any treatment. Meningiomas are usually common and benign intracranial tumors; however, the anaplastic subtype of meningiomas is rare and malignant. Despite the high rates of recurrence and metastasis, surgery is still an option. For giant invasive tumors, the cooperation of neurosurgeons and plastic surgeons is essential.
authors.affiliation: Department of Plastic Surgery, West China Hospital of Sichuan University, Chengdu, Sichuan Province, PR China. lizydd@sina.com
authors.forename: Zheng-yong
authors.initials: ZY
authors.lastname: Li
authors.forename: Ying
authors.initials: Y
authors.lastname: Cen
authors.forename: Mingjing
authors.initials: M
authors.lastname: Gu
authors.forename: Yating
authors.initials: Y
authors.lastname: Wei
mesh_terms: D000368:Aged; D003399:Craniotomy / Q000379:methods; D017809:Fatal Outcome; D005260:Female; D005624:Frontal Bone / Q000473:pathology* / Q000601:surgery*; D006801:Humans; D008577:Meningeal Neoplasms / Q000473:pathology* / Q000601:surgery*; D008579:Meningioma / Q000473:pathology* / Q000601:surgery*; D009361:Neoplasm Invasiveness; D012535:Scalp / Q000473:pathology* / Q000601:surgery*; D012888:Skull Neoplasms / Q000473:pathology* / Q000601:surgery*; D013524:Surgical Flaps