title: Expression of P2X receptor subtypes on CD34+ cells and c-kit+ cells of human umbilical blood.
abstract: The presence of several subtypes of P2X receptors on early hemopoietic precursors (CD34+) from human umbilical blood was detected by flow cytometry. The expression of P2X receptors on umbilical blood lymphocytes was an order of magnitude higher than that on adult human blood cells. Our results attest to early involvement of P2X receptors in differentiation of human hemopoietic cells.
authors.affiliation: Kazan State Medical University, Russia. kazakovarenata@rambler.ru
authors.forename: R R
authors.initials: RR
authors.lastname: Kazakova
authors.forename: I G
authors.initials: IG
authors.lastname: Mustafin
authors.forename: T I
authors.initials: TI
authors.lastname: Mavludov
authors.forename: A P
authors.initials: AP
authors.lastname: Kiyasov
authors.forename: A U
authors.initials: AU
authors.lastname: Ziganshin
mesh_terms: D018952:Antigens, CD34 / Q000097:blood; D015415:Biomarkers / Q000097:blood; D001772:Blood Cell Count; D002454:Cell Differentiation; D005312:Fetal Blood / Q000166:cytology / Q000378:metabolism*; D005434:Flow Cytometry; D015870:Gene Expression; D006412:Hematopoietic Stem Cells / Q000166:cytology / Q000378:metabolism*; D006801:Humans; D008214:Lymphocytes / Q000166:cytology / Q000378:metabolism; D019009:Proto-Oncogene Proteins c-kit / Q000097:blood*; D058469:Receptors, Purinergic P2X / Q000097:blood*
chemical_list: D018952:Antigens, CD34; D015415:Biomarkers; D058469:Receptors, Purinergic P2X; D019009:Proto-Oncogene Proteins c-kit