title: Targeted next-generation sequencing expands the spectrum of mitochondrial disorders.
abstract: Next-generation sequencing has become a powerful tool for testing genetically and clinically heterogeneous conditions such as mitochondrial disorders. A recent study published in Science Translational Medicine underscores the considerable clinical benefits of targeted next-generation sequencing for the diagnosis of mitochondrial disorders. The findings also suggest that the genetic heterogeneity that can result in mitochondrial disease appears much broader than previously thought.
authors.affiliation: Department of Pediatrics, Division of Genetic Medicine, University of Washington School of Medicine, Seattle Children's Hospital, Seattle, WA 98105, USA.
authors.forename: Si Houn
authors.initials: SH
authors.lastname: Hahn