title: Short-term outcome of Boston Type 1 keratoprosthesis for bilateral limbal stem cell deficiency.
abstract: This study reports the short-term functional and anatomical outcome of Boston Type 1 keratoprosthesis (Boston Kpro) implantation for bilateral limbal stem cell deficiency (LCSD). Retrospective analysis was done on eight eyes of eight patients who underwent Boston Kpro implantation between July 2009 and October 2009. The best corrected visual acuity (BCVA) and slit-lamp biomicroscopy findings were assessed at 1, 3 and 6 months postoperatively. All eight eyes retained the prosthesis. BCVA of 20/40 or better was achieved in 8, 6, and 5 eyes at 1, 3, and 6 months, respectively, postoperatively. One patient each developed epithelial defect, sterile stromal melt and fungal keratitis in the late postoperative period associated with antecedent loss of the soft contact lens from the eye. Boston Kpro has good short-term visual and anatomical outcome in patients with bilateral LSCD, provided compliance with postoperative care can be ensured.
authors.affiliation: Cornea & Anterior Segment Service, LV Prasad Eye Institute, Kallam Anji Reddy Campus, Banjara Hills, Hyderabad, India.
authors.forename: Sayan
authors.initials: S
authors.lastname: Basu
authors.forename: Mukesh
authors.initials: M
authors.lastname: Taneja
authors.forename: Raja
authors.initials: R
authors.lastname: Narayanan
authors.forename: Sirisha
authors.initials: S
authors.lastname: Senthil
authors.forename: Virender S
authors.initials: VS
authors.lastname: Sangwan
mesh_terms: D000293:Adolescent; D000328:Adult; D001766:Blindness / Q000209:etiology / Q000601:surgery*; D003316:Corneal Diseases / Q000150:complications / Q000473:pathology / Q000601:surgery*; D005500:Follow-Up Studies; D006801:Humans; D016850:Limbus Corneae / Q000473:pathology*; D008875:Middle Aged; D019736:Prostheses and Implants; D012189:Retrospective Studies; D013234:Stem Cells / Q000473:pathology*; D016896:Treatment Outcome; D055815:Young Adult