title: [Therapeutic advances in refractory epilepsies in children].
abstract: Epilepsy concerns several thousands of children in Switzerland, and is refractory to classic antiepileptic drugs in an important proportion of cases. This percentage has remained stable, despite a constant production of new antiepileptic molecules. To alleviate this problem, several alternative approaches have been developed these last years. In this article, we present three children who suffer from different forms of pharmacoresistant epilepsy, managed with immunomodulatory or neurosurgical treatments, and we summarize the current knowledge about these therapeutic options.
authors.affiliation: Neuropédiatrie Service des spécialités pédiatriques, Département de l'enfant et de l'adolescent, HUG, 1211 Genève 14. christian.korff@hcuge.ch
authors.forename: Christian M
authors.initials: CM
authors.lastname: Korff
authors.forename: Sébastien
authors.initials: S
authors.lastname: Lebon
authors.forename: Eliane
authors.initials: E
authors.lastname: Roulet-Perez
mesh_terms: D002648:Child; D004827:Epilepsy / Q000628:therapy*; D005260:Female; D006801:Humans; D007231:Infant, Newborn