title: Whole genome studies of Tetrahymena.
abstract: Within the past decade, genomic studies have emerged as essential and highly productive tools to explore the biology of Tetrahymena thermophila. The current major resources, which have been extensively mined by the research community, are the annotated macronuclear genome assembly, transcriptomic data and the databases that house this information. Efforts in progress will soon improve these data sources and expand their scope, including providing annotated micronuclear and comparative genomic sequences. Future studies of Tetrahymena cell and molecular biology, development, physiology, evolution and ecology will benefit greatly from these resources and the advanced genomic technologies they enable.
authors.affiliation: Department of Genomic Medicine, J. Craig Venter Institute, Rockville, MD, USA.
authors.forename: Robert S
authors.initials: RS
authors.lastname: Coyne
authors.forename: Nicholas A
authors.initials: NA
authors.lastname: Stover
authors.forename: Wei
authors.initials: W
authors.lastname: Miao
mesh_terms: D018528:ATP-Binding Cassette Transporters / Q000235:genetics / Q000378:metabolism; D022004:Chromosome Structures / Q000235:genetics / Q000378:metabolism; D002875:Chromosomes / Q000235:genetics / Q000378:metabolism; D003577:Cytochrome P-450 Enzyme System / Q000235:genetics / Q000378:metabolism; D016054:DNA, Protozoan / Q000235:genetics / Q000378:metabolism; D030541:Databases, Genetic; D019143:Evolution, Molecular; D020869:Gene Expression Profiling; D014644:Genetic Variation; D018503:Genome, Protozoan; D007425:Intracellular Membranes / Q000378:metabolism; D048648:Macronucleus / Q000235:genetics* / Q000378:metabolism; D048631:Micronucleus, Germline / Q000235:genetics* / Q000378:metabolism; D058977:Molecular Sequence Annotation; D010802:Phylogeny; D040901:Proteomics / Q000379:methods; D016053:RNA, Protozoan / Q000235:genetics / Q000378:metabolism; D016808:Tetrahymena thermophila / Q000145:classification / Q000235:genetics* / Q000378:metabolism; D059467:Transcriptome
chemical_list: D018528:ATP-Binding Cassette Transporters; D016054:DNA, Protozoan; D016053:RNA, Protozoan; D003577:Cytochrome P-450 Enzyme System