title: [Bilateral Achilles tendon rupture following levofloxacin and glucocorticoid use].
abstract: The combination of fluorquinolones and glucocorticoids leads to a high risk of tendon rupture. Especially the Achilles tendon is at risk. We present a report of a 65-year-old woman with a bilateral Achilles tendon rupture following use of levofloxacin and corticosteroids for pneumonia. Symptoms of the tendons in patients using glucocorticoids and fluorquinolones should be evaluated. The physician should be aware of the high risk of an Achilles tendon rupture, particularly in older patients using this combination.
authors.affiliation: Leids Universitair Medisch Centrum, afd. Orthopedie, Leiden, The Netherlands. laura.m.kok@gmail.com
authors.forename: Laura M
authors.initials: LM
authors.lastname: Kok
authors.forename: Menno R
authors.initials: MR
authors.lastname: Bénard
authors.forename: Ewoud R A
authors.initials: ER
authors.lastname: van Arkel
mesh_terms: D000125:Achilles Tendon / Q000293:injuries*; D000368:Aged; D000890:Anti-Infective Agents / Q000009:adverse effects / Q000627:therapeutic use; D002370:Casts, Surgical; D005260:Female; D005938:Glucocorticoids / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D064704:Levofloxacin; D015242:Ofloxacin / Q000009:adverse effects* / Q000627:therapeutic use; D011014:Pneumonia / Q000188:drug therapy; D012421:Rupture / Q000139:chemically induced
chemical_list: D000890:Anti-Infective Agents; D005938:Glucocorticoids; D064704:Levofloxacin; D015242:Ofloxacin