title: Obesity and laparoscopic colectomy: outcomes from the ACS-NSQIP database.
abstract: BACKGROUND
  Previous reports comparing outcomes of laparoscopic colectomy in obese vs nonobese patients from small, single-institution series have included few obese patients and have shown variable results, some suggesting that obesity has no impact on outcomes.
  
  
  OBJECTIVE
  We aimed to determine whether any intraoperative or short-term postoperative outcome of laparoscopic colectomy is affected by obesity, independent of other variables.
  
  
  METHODS
  We performed a retrospective study comparing outcomes of patients undergoing laparoscopic colectomy grouped by BMI.
  
  
  METHODS
  We queried American College of Surgeons National Surgical Quality Improvement Program Participant Use Data Files for patients undergoing nonemergent, laparoscopic colectomy from 2005 through 2008. Cases with a secondary procedure (with the exception of laparoscopic lysis of adhesions, rigid proctosigmoidoscopy, or laparoscopic splenic flexure takedown) were excluded.
  
  
  METHODS
  We analyzed operative time, length of stay, transfusion requirement, reoperation within 30 days, wound complications, pulmonary complications, sepsis/septic shock, deep venous thrombosis, renal failure/insufficiency, and death. We tested for differences in outcomes using χ tests or analyses of variance, and when differences between BMI classes were found, we performed multivariable regression to adjust for preoperative and intraoperative variables.
  
  
  RESULTS
  In an analysis of 9693 patients (30% with BMI ≥30), significant differences were found among BMI classes for length of stay, operative time, and wound complication. Operative time correlated with BMI class independent of other variables; length of stay did not. After adjustment of all available variables, obesity remained an independent risk factor for wound complication, and the odds ratios increased with increasing obesity class.
  
  
  CONCLUSIONS
  Retrospective design and standardized outcome measures prevent examination of procedure-specific outcomes; therefore, this is not an intention-to-treat analysis.
  
  
  CONCLUSIONS
  These data confirm that, in patients undergoing laparoscopic colectomy, obesity is an independent risk factor for wound complications. Although obesity also increases operative time, the effect of obesity on wound complications remains after adjustment for this and other risk factors.
authors.affiliation: Department of Surgery, University of Kentucky, Lexington, KY, USA.
authors.forename: W Conan
authors.initials: WC
authors.lastname: Mustain
authors.forename: Daniel L
authors.initials: DL
authors.lastname: Davenport
authors.forename: Jon S
authors.initials: JS
authors.lastname: Hourigan
authors.forename: H David
authors.initials: HD
authors.lastname: Vargas
mesh_terms: D000704:Analysis of Variance; D001803:Blood Transfusion / Q000706:statistics & numerical data; D016009:Chi-Square Distribution; D003082:Colectomy / Q000379:methods*; D005260:Female; D006801:Humans; D010535:Laparoscopy / Q000379:methods*; D007902:Length of Stay / Q000706:statistics & numerical data; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000150:complications*; D011183:Postoperative Complications; D012044:Regression Analysis; D012086:Reoperation; D012189:Retrospective Studies; D013997:Time Factors; D016896:Treatment Outcome