title: Effect of placenta previa on fetal growth restriction and stillbirth.
abstract: OBJECTIVE
  To examine the association between placenta previa and adverse perinatal outcomes such as low birth weight, preterm delivery, stillbirth and fetal growth restriction (FGR).
  
  
  METHODS
  This retrospective cohort study includes 12,034 delivered pregnant women who were recruited for the study between 2004 and 2010 in Ege University Hospital. Data were collected by browsing the clinic's archives. The association between placenta previa and adverse perinatal outcomes was determined via Chi-square tests and Student's t test. Logistic regression analysis was used to adjust for confounding factors in evaluating the association between placenta previa and the adverse perinatal outcomes.
  
  
  RESULTS
  There was no significant relationship between placenta previa and FGR or stillbirth. Low birth weight and preterm delivery were significantly higher in the placenta previa group. According to logistic regression analysis, low birth weight was associated with an OR of 3.01 (95 % CI 2.05-4.52) and preterm delivery was associated with an OR of 8.14 (95 % CI 5.60-11.83); while, placenta previa did not affect FGR and stillbirth significantly.
  
  
  CONCLUSIONS
  Although there is no consensus on the association between placenta previa and FGR in previous studies, we suggest that placenta previa is not a reason for placental insufficiency. Management of placenta previa especially depends on maternal hemodynamic parameters such as heavy hemorrhage and hypotensive shock rather than fetal well-being protocols based on serial growth ultrasound and fetal Doppler investigation.
authors.affiliation: Department of Obstetrics and Gynecology, Faculty of Medicine, Ege University, Bornova, Izmir 35100, Turkey. drayeniel@hotmail.com
authors.forename: A Ozgur
authors.initials: AO
authors.lastname: Yeniel
authors.forename: A Mete
authors.initials: AM
authors.lastname: Ergenoglu
authors.forename: Ismail Mete
authors.initials: IM
authors.lastname: Itil
authors.forename: Niyazi
authors.initials: N
authors.lastname: Askar
authors.forename: Reci
authors.initials: R
authors.lastname: Meseri
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D005317:Fetal Growth Retardation / Q000209:etiology*; D006801:Humans; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D010923:Placenta Previa / Q000453:epidemiology*; D011247:Pregnancy; D047928:Premature Birth / Q000453:epidemiology; D012189:Retrospective Studies; D050497:Stillbirth; D055815:Young Adult