title: New insights into the SAGA complex from studies of the Tra1 subunit in budding and fission yeast.
abstract: The SAGA complex is a conserved, multifunctional co-activator that controls the transcription of many inducible genes in response to environmental changes. Recent studies have provided new insights into the functions of one of its subunits, Tra1/TRRAP, and suggest that it controls SAGA activity in response to external stimuli.
authors.affiliation: Macromolecular Biochemistry Research Center, CNRS UMR 5237, University of Montpellier 1 & 2, Montpellier, France. dhelmlinger@crbm.cnrs.fr
authors.forename: Dominique
authors.initials: D
authors.lastname: Helmlinger
mesh_terms: D048868:Adaptor Proteins, Signal Transducing / Q000737:chemistry / Q000378:metabolism; D000818:Animals; D051548:Histone Acetyltransferases / Q000737:chemistry / Q000378:metabolism*; D006801:Humans; D051379:Mice; D009687:Nuclear Proteins / Q000737:chemistry / Q000378:metabolism; D012441:Saccharomyces cerevisiae / Q000378:metabolism*; D029701:Saccharomyces cerevisiae Proteins / Q000737:chemistry / Q000378:metabolism*; D012568:Schizosaccharomyces / Q000378:metabolism*; D029702:Schizosaccharomyces pombe Proteins / Q000378:metabolism*; D015398:Signal Transduction; D015534:Trans-Activators / Q000737:chemistry / Q000378:metabolism*
chemical_list: D048868:Adaptor Proteins, Signal Transducing; D009687:Nuclear Proteins; C507785:SAGA complex, S cerevisiae; D029701:Saccharomyces cerevisiae Proteins; D029702:Schizosaccharomyces pombe Proteins; C491364:TRA1 protein, S cerevisiae; D015534:Trans-Activators; C113829:transformation-transcription domain-associated protein; D051548:Histone Acetyltransferases