title: Chemical Analysis and Study of Phenolics, Antioxidant Activity, and Antibacterial Effect of the Wood and Bark of Maclura tinctoria (L.) D. Don ex Steud.
abstract: Maclura tinctoria (L.) D. Don ex Steud. has one of the highest qualities among the coefficients for Brazilian woods (up to 9.6) and resistance rates equivalent to Indian teak (Tectona grandis). In this study, the macromolecular constituents and total phenols compounds as well as the antioxidant and antibacterial activities of this wood were evaluated. Total phenols and proanthocyanidin levels were higher in wood when compared with bark levels. The antioxidant activity of wood extracts (IC(50) = 18.7 μg/mL) was more effective than that of bark extracts (IC(50) = 20.9 μg/mL). Wood and bark extracts revealed a high potential for inhibition of aerobic and anaerobic bacteria. The bark extracts were the most active (MIC from 20 to 60 μg/mL). Both antioxidant activity and high potential for bacteria inhibition turn these extracts promising for drug formulations, especially as antibacterial agent.
authors.affiliation: Instituto de Química, Universidade Federal de Uberlândia, Avenida João Naves de Ávila 2121, 38400-902 Uberlândia, MG, Brazil.
authors.forename: K C
authors.initials: KC
authors.lastname: Lamounier
authors.forename: L C S
authors.initials: LC
authors.lastname: Cunha
authors.forename: S A L
authors.initials: SA
authors.lastname: de Morais
authors.forename: F J T
authors.initials: FJ
authors.lastname: de Aquino
authors.forename: R
authors.initials: R
authors.lastname: Chang
authors.forename: E A
authors.initials: EA
authors.lastname: do Nascimento
authors.forename: M G M
authors.initials: MG
authors.lastname: de Souza
authors.forename: C H G
authors.initials: CH
authors.lastname: Martins
authors.forename: W R
authors.initials: WR
authors.lastname: Cunha