title: Multisubstituted furan formation from (Z)- or (E)-enynyl acetates: tandem reactions accelerated by electron-donating groups on aromatic rings.
abstract: Multisubstituted furans were readily prepared from (Z)- or (E)-conjugated enynyl acetates with NXS under metal-free conditions at room temperature via the same haloallenyl ketone intermediates. This tandem haloallenyl ketone formation-furan formation reaction sequence was accelerated by electron-donating groups on the aromatic rings.
authors.affiliation: Faculty of Pharmaceutical Sciences, Hiroshima International University, 5-1-1 Hirokoshingai, Kure, Hiroshima 737-0112, Japan.
authors.forename: Noriko
authors.initials: N
authors.lastname: Okamoto
authors.forename: Reiko
authors.initials: R
authors.lastname: Yanada
mesh_terms: D000085:Acetates / Q000737:chemistry*; D000466:Alkadienes / Q000737:chemistry*; D004583:Electrons; D005663:Furans / Q000737:chemistry*; D007659:Ketones / Q000737:chemistry*; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D000085:Acetates; D000466:Alkadienes; D005663:Furans; D007659:Ketones; C039281:furan