title: Digitalis toxicity: a fading but crucial complication to recognize.
abstract: Digoxin usage has decreased in the treatment of congestive heart failure and atrial fibrillation as a result of its inferiority to beta-adrenergic inhibitors and agents that interfere with the deleterious effects of the activated renin-angiotensin-aldosterone system. As a result of reduction of usage and dosage, glycoside toxicity has become an uncommon occurrence but may be overlooked when it does occur. Older age, female sex, low lean body mass, and renal insufficiency contribute to higher serum levels and enhanced risk for toxicity. Arrhythmias suggesting digoxin toxicity led to its recognition in the case presented here.
authors.affiliation: Division of Cardiology, Department of Medicine, University of California at Los Angeles, Los Angeles, CA 90095, USA. Datsunian@gmail.com
authors.forename: Eric H
authors.initials: EH
authors.lastname: Yang
authors.forename: Sonia
authors.initials: S
authors.lastname: Shah
authors.forename: John M
authors.initials: JM
authors.lastname: Criley
mesh_terms: D000368:Aged; D001145:Arrhythmias, Cardiac / Q000139:chemically induced* / Q000150:complications; D004071:Digitalis Glycosides / Q000506:poisoning*; D006801:Humans; D008297:Male
chemical_list: D004071:Digitalis Glycosides