title: Outcomes of conservative surgery in early epithelial ovarian carcinoma.
abstract: OBJECTIVE
  To investigate clinical outcomes and fertility status of conservative treatment for epithelial ovarian carcinoma.
  
  
  METHODS
  The data of clinicopathological characteristics and follow-up were retrospectively collected and analyzed in 17 patients with early epithelial ovarian carcinoma who underwent conservative surgery.
  
  
  RESULTS
  The tumor histologic types of 17 patients included 13 mucinous, one serous, one endometrioid, and two mixed mucinous and serous carcinomas. The FIGO stages were: ten Stage IA, six IC, and one IIIA disease. Tumor grades involved 15 grade 1 and two grade 2. Sixteen patients received adjuvant platinum-based combined chemotherapy. The medium duration of follow-up was 61 months (range 17-115 months). Only one patient recurred at 36 months after primary surgery. All of the 17 patients were alive at end of follow-up. Eight patients attempted pregnancy and five patients conceived naturally; there were six term pregnancies and one abortion.
  
  
  CONCLUSIONS
  Conservative surgery can be considered for young patients with FIGO Stage I including grade 1 and grade 2 epithelial ovarian cancers who desire further childbearing.
authors.affiliation: Department of Gynecologic Oncology, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou, China. chengbei128@gmail.com
authors.forename: X
authors.initials: X
authors.lastname: Cheng
authors.forename: B
authors.initials: B
authors.lastname: Cheng
authors.forename: X
authors.initials: X
authors.lastname: Wan
authors.forename: W
authors.initials: W
authors.lastname: Lu
authors.forename: X
authors.initials: X
authors.lastname: Xie
mesh_terms: D000293:Adolescent; D000328:Adult; D000077216:Carcinoma, Ovarian Epithelial; D005260:Female; D005298:Fertility; D059247:Fertility Preservation; D005500:Follow-Up Studies; D006801:Humans; D060787:Neoplasm Grading; D009364:Neoplasm Recurrence, Local / Q000188:drug therapy / Q000473:pathology / Q000601:surgery; D009367:Neoplasm Staging; D009375:Neoplasms, Glandular and Epithelial / Q000473:pathology / Q000601:surgery*; D059351:Organ Sparing Treatments; D010051:Ovarian Neoplasms / Q000473:pathology / Q000601:surgery*; D011247:Pregnancy; D011256:Pregnancy Outcome; D012189:Retrospective Studies; D016896:Treatment Outcome; D055815:Young Adult