title: IOM committee members respond to Endocrine Society vitamin D guideline.
abstract: In early 2011, a committee convened by the Institute of Medicine issued a report on the Dietary Reference Intakes for calcium and vitamin D. The Endocrine Society Task Force in July 2011 published a guideline for the evaluation, treatment, and prevention of vitamin D deficiency. Although these reports are intended for different purposes, the disagreements concerning the nature of the available data and the resulting conclusions have caused confusion for clinicians, researchers, and the public. In this commentary, members of the Institute of Medicine committee respond to aspects of The Endocrine Society guideline that are not well supported and in need of reconsideration. These concerns focus on target serum 25-hydroxyvitamin D levels, the definition of vitamin D deficiency, and the question of who constitutes a population at risk vs. the general population.
authors.affiliation: Maine Medical Center Research Institute, 81 Research Drive, Scarborough, Maine 04074, USA. crofen@gmail.com
authors.forename: Clifford J
authors.initials: CJ
authors.lastname: Rosen
authors.forename: Steven A
authors.initials: SA
authors.lastname: Abrams
authors.forename: John F
authors.initials: JF
authors.lastname: Aloia
authors.forename: Patsy M
authors.initials: PM
authors.lastname: Brannon
authors.forename: Steven K
authors.initials: SK
authors.lastname: Clinton
authors.forename: Ramon A
authors.initials: RA
authors.lastname: Durazo-Arvizu
authors.forename: J Christopher
authors.initials: JC
authors.lastname: Gallagher
authors.forename: Richard L
authors.initials: RL
authors.lastname: Gallo
authors.forename: Glenville
authors.initials: G
authors.lastname: Jones
authors.forename: Christopher S
authors.initials: CS
authors.lastname: Kovacs
authors.forename: JoAnn E
authors.initials: JE
authors.lastname: Manson
authors.forename: Susan T
authors.initials: ST
authors.lastname: Mayne
authors.forename: A Catharine
authors.initials: AC
authors.lastname: Ross
authors.forename: Sue A
authors.initials: SA
authors.lastname: Shapses
authors.forename: Christine L
authors.initials: CL
authors.lastname: Taylor
mesh_terms: D015652:25-Hydroxyvitamin D 2 / Q000097:blood; D000367:Age Factors; D002112:Calcifediol / Q000097:blood; D002136:Calcium, Dietary / Q000378:metabolism; D004704:Endocrinology / Q000639:trends; D005260:Female; D006293:Health Promotion; D006801:Humans; D007408:Intestinal Absorption; D007774:Lactation / Q000378:metabolism; D008297:Male; D015969:National Academies of Science, Engineering, and Medicine, U.S., Health and Medicine Division; D009751:Nutritional Requirements / Q000208:ethnology; D010281:Parathyroid Hormone / Q000097:blood; D017410:Practice Guidelines as Topic; D011247:Pregnancy; D012958:Societies, Scientific; D014481:United States; D014807:Vitamin D / Q000008:administration & dosage* / Q000378:metabolism; D014808:Vitamin D Deficiency / Q000097:blood / Q000175:diagnosis / Q000208:ethnology / Q000517:prevention & control*
chemical_list: D002136:Calcium, Dietary; C470125:PTH protein, human; D010281:Parathyroid Hormone; D014807:Vitamin D; D015652:25-Hydroxyvitamin D 2; D002112:Calcifediol