title: Molecular phylogenetics: principles and practice.
abstract: Phylogenies are important for addressing various biological questions such as relationships among species or genes, the origin and spread of viral infection and the demographic changes and migration patterns of species. The advancement of sequencing technologies has taken phylogenetic analysis to a new height. Phylogenies have permeated nearly every branch of biology, and the plethora of phylogenetic methods and software packages that are now available may seem daunting to an experimental biologist. Here, we review the major methods of phylogenetic analysis, including parsimony, distance, likelihood and Bayesian methods. We discuss their strengths and weaknesses and provide guidance for their use.
authors.affiliation: Center for Computational and Evolutionary Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China. z.yang@ucl.ac.uk
authors.forename: Ziheng
authors.initials: Z
authors.lastname: Yang
authors.forename: Bruce
authors.initials: B
authors.lastname: Rannala
mesh_terms: D001483:Base Sequence; D005260:Female; D006801:Humans; D008297:Male; D008954:Models, Biological; D015233:Models, Statistical; D008969:Molecular Sequence Data; D010802:Phylogeny; D012984:Software