title: [Contrast-enhanced ultrasound imaging features of diabetic foot ulcers].
abstract: OBJECTIVE
  To investigate contrast-enhanced ultrasound imaging features of diabetic foot ulcers.
  
  
  METHODS
  Sixteen patients with diabetic foot ulcers underwent conventional and contrast-enhanced ultrasound examinations, and the features of contrast-enhanced ultrasound imaging were analyzed. Pathological examination was also carried out in some cases.
  
  
  RESULTS
  Contrast-enhanced ultrasound showed slow enhancement in the artery phase in the 16 ulcers after administration of SonoVue. The mean time of initial enhancement was 30.02 ± 2.35 s, and the mean time for the occurrence of peak enhancement was 37.54 ± 4.13 s. In 5 cases a homogeneous enhancement pattern was clearly displayed, and in the other 11 cases, a pattern of homogenous peripheral enhancement with non-enhanced patches within the ulcers was found. Contrast-enhanced ultrasound showed a greater ulcerous area than conventional ultrasound.
  
  
  CONCLUSIONS
  Contrast-enhanced ultrasound is a valuable means for evaluating the ulcerous area and the treatment efficacy for diabetic foot ulcers.
authors.affiliation: Department of Ultrasound, First Affiliated Hospital of Jinan University, Guangzhou 510630, China.
authors.forename: Xia
authors.initials: X
authors.lastname: Zhang
authors.forename: Hong-Wei
authors.initials: HW
authors.lastname: Liu
authors.forename: Ya-Ci
authors.initials: YC
authors.lastname: Lv
authors.forename: Jun
authors.initials: J
authors.lastname: Huang
authors.forename: Xing
authors.initials: X
authors.lastname: Zhong
authors.forename: Jian-Li
authors.initials: JL
authors.lastname: Shao
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003287:Contrast Media; D017719:Diabetic Foot / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D008297:Male; D008875:Middle Aged; D010743:Phospholipids; D013459:Sulfur Hexafluoride; D014463:Ultrasonography
chemical_list: D003287:Contrast Media; D010743:Phospholipids; C420843:contrast agent BR1; D013459:Sulfur Hexafluoride