title: Airway stenting for emphysema: back to the drawing board.
abstract: In a recent report, authors describe their findings from the Exhale Airway Stents for Emphysema (EASE) trial. In this study, investigators follow patients with emphysema and severe hyperinflation after a novel bronchoscopic lung-volume reduction procedure utilizing paclitaxel-eluting stents. Despite the merits of this randomized, sham-controlled, multi-institutional study, the authors were unable to demonstrate any sustainable benefit for the treatment group upon follow-up. Nonetheless, important lessons can be learned from this trial, which has set a foundation for future investigations.
authors.forename: Mara B
authors.initials: MB
authors.lastname: Antonoff
authors.forename: Jonathan
authors.initials: J
authors.lastname: D'Cunha
mesh_terms: D001999:Bronchoscopy / Q000295:instrumentation*; D054855:Drug-Eluting Stents; D006801:Humans; D017239:Paclitaxel / Q000008:administration & dosage*; D011474:Prosthesis Design; D011656:Pulmonary Emphysema / Q000503:physiopathology / Q000601:surgery*; D019141:Respiratory System Agents / Q000008:administration & dosage*; D016896:Treatment Outcome
chemical_list: D019141:Respiratory System Agents; D017239:Paclitaxel