title: Chitosan whiskers from shrimp shells incorporated into dimethacrylate-based dental resin sealant.
abstract: A resin-based sealant containing chitosan whiskers was developed for use as a pit and fissure sealer. Chitosan whiskers were synthesized and then characterized using Fourier transform infrared spectrometry and transmission electron microscopy. The whiskers were next incorporated into dimethacrylate monomer at various ratios by weight and subsequently analyzed for their antimicrobial and physical properties. The dimethacrylate-based sealant containing chitosan whiskers had a greater antimicrobial activity than control sealant and they were comparable with antimicrobial commercial resin sealants. The inclusion of the whiskers did not reduce the curing depth or degree of double bond conversion and the reduction in hardness was minimal. In conclusion, a resin-based sealant containing chitosan whiskers can be considered an effective antimicrobial pit and fissure sealant.
authors.affiliation: Department of Operative Dentistry, Faculty of Dentistry, Chulalongkorn University, Bangkok 10330, Thailand.
authors.forename: Ekamon
authors.initials: E
authors.lastname: Mahapoka
authors.forename: Pratanporn
authors.initials: P
authors.lastname: Arirachakaran
authors.forename: Anyarat
authors.initials: A
authors.lastname: Watthanaphanit
authors.forename: Ratana
authors.initials: R
authors.lastname: Rujiravanit
authors.forename: Suchit
authors.initials: S
authors.lastname: Poolthong
mesh_terms: D060105:Animal Shells / Q000737:chemistry; D000818:Animals; D048271:Chitosan / Q000737:chemistry* / Q000494:pharmacology; D015169:Colony Count, Microbial; D006244:Hardness; D055115:Light-Curing of Dental Adhesives; D008422:Materials Testing; D015394:Molecular Structure; D033561:Penaeidae; D010895:Pit and Fissure Sealants / Q000138:chemical synthesis* / Q000737:chemistry* / Q000494:pharmacology; D011109:Polymethacrylic Acids; D019279:Resin Cements / Q000138:chemical synthesis* / Q000737:chemistry* / Q000494:pharmacology; D017550:Spectroscopy, Fourier Transform Infrared; D013295:Streptococcus mutans / Q000187:drug effects*
chemical_list: D010895:Pit and Fissure Sealants; D011109:Polymethacrylic Acids; D019279:Resin Cements; D048271:Chitosan