title: [Critical analysis on risk factors of postoperative in-hospital complications in radical cystectomy of bladder cancer].
abstract: OBJECTIVE
  To evaluate the risk factors associated with the in-hospital complications of radical cystectomy.
  
  
  METHODS
  The records of 128 consecutive patients who underwent radical cystectomy from November 2006 to October 2009 were reviewed. Preoperative, intraoperative risk variables were defined based on POSSUM score and APACHE II score. ASA score and m-ACCI score were used to evaluate the co-mobidities. All variables were analyzed to evaluate the risk factors associated with in-hospital complications of radical cystectomy.
  
  
  RESULTS
  In the 128 patients undergoing radical cystectomy, 58 patients (45.31%) had complications, with 51 (39.84%) minor complicatons and 7 (5.47%) major complications. Wound dehiscence or unhealing (22.66%), infection (20.31%) and ileus (17.19%) were the most common complications. The risk factors related to the in-hospital complications of radical cystectomy are age > or = 65 yr. (P < 0.001,OR = 1.067), volume of intraoperative blood transfusion > or = 600 mL (P = 0.023, OR = 1.001), m-ACCI score (P < 0.001, OR = 1.583), ASA score > or = III (P = 0.003, OR = 2.411), partial cystectomy history (P = 0.025 OR = 2.444), intraoperative heart rate > 120 beats/min (P < 0.001, OR = 11.861).
  
  
  CONCLUSIONS
  Wound complication, postoperative infection and ileus are the most common complications of radical cystectomy. Age, volume of intraoperative blood transfusion, m-ACCI score, ASA score, partial cystectomy history and intraoperative heart rate are significant risk factors.
authors.affiliation: Department of Urology, West China Hospital, Sichuan University, Chengdu 610041, China.
authors.forename: Yu
authors.initials: Y
authors.lastname: Fan
authors.forename: Ming
authors.initials: M
authors.lastname: Shi
authors.forename: Zi-Bin
authors.initials: ZB
authors.lastname: Xiong
authors.forename: Ping
authors.initials: P
authors.lastname: Han
authors.forename: Peng
authors.initials: P
authors.lastname: Zhang
authors.forename: Hao
authors.initials: H
authors.lastname: Zeng
authors.forename: Xiang
authors.initials: X
authors.lastname: Li
authors.forename: Qiang
authors.initials: Q
authors.lastname: Wei
mesh_terms: D000368:Aged; D002277:Carcinoma / Q000601:surgery; D015653:Cystectomy / Q000009:adverse effects*; D005260:Female; D006801:Humans; D045823:Ileus / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000209:etiology; D012189:Retrospective Studies; D012307:Risk Factors; D013530:Surgical Wound Infection / Q000209:etiology*; D001749:Urinary Bladder Neoplasms / Q000601:surgery*; D014547:Urinary Diversion