title: Antithrombotic therapy in patients with acute coronary syndrome and diabetes mellitus.
abstract: Acute coronary syndrome (ACS) is associated with high mortality even in the acute phase as well as in the post-acute (chronic) phase. Diabetes mellitus type 2 (DM-2), on the other hand, further increases mortality after ACS. Several new antiplatelet and antithrombotic drugs available for clinical use have also been investigated in patients with DM-2, and the guidelines of the European Society of Cardiology (ESC) were recently adapted. However, in daily clinical practice choosing the most suitable regimen is a challenge in many cases. This review article aims to shed light on and simplify antiplatelet and antithrombotic therapy in ACS patients with DM-2 in order to ease the clinician's decision-making.
authors.affiliation: 3rd Department of Medicine, Cardiology and Emergency Medicine, Wilhelminenhospital, Vienna, Montleartstr. 37, 1160, Vienna, Austria. serdarfarhan@yahoo.de
authors.forename: S
authors.initials: S
authors.lastname: Farhan
authors.forename: I
authors.initials: I
authors.lastname: Tentzeris
authors.forename: M K
authors.initials: MK
authors.lastname: Freynhofer
authors.forename: B
authors.initials: B
authors.lastname: Vogel
authors.forename: K
authors.initials: K
authors.lastname: Huber
mesh_terms: D054058:Acute Coronary Syndrome / Q000188:drug therapy / Q000209:etiology* / Q000517:prevention & control*; D003924:Diabetes Mellitus, Type 2 / Q000150:complications* / Q000188:drug therapy*; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D006801:Humans; D016896:Treatment Outcome
chemical_list: D005343:Fibrinolytic Agents