title: Effect of meadowsweet (Filipendula vulgaris) extract on bioenergetics of the brain during experimental posthypoxic encephalopathy.
abstract: We studied the effect of Filipendula vulgaris aqueous extract on mitochondrial energy production system in the brain of rats with posthypoxic encephalopathy developing 19 days after hypoxic injury. Filipendula extract more effectively than valerian extract improved kinetic characteristics of respiratory activity of mitochondria, increased substrate oxidation-phosphorylation coupling, and inhibited LPO.
authors.affiliation: Department of Pharmacology, Siberian State Medical University, Tomsk, Russia. pharmsibgmu@rambler.ru
authors.forename: A I
authors.initials: AI
authors.lastname: Vengerovsky
authors.forename: N I
authors.initials: NI
authors.lastname: Suslov
authors.forename: A V
authors.initials: AV
authors.lastname: Kaygorodsev
mesh_terms: D000818:Animals; D001921:Brain / Q000187:drug effects* / Q000378:metabolism; D004734:Energy Metabolism / Q000187:drug effects*; D031984:Filipendula / Q000737:chemistry*; D002534:Hypoxia, Brain / Q000378:metabolism*; D008297:Male; D010936:Plant Extracts / Q000494:pharmacology*; D051381:Rats
chemical_list: D010936:Plant Extracts