title: Cerebral venous sinus thrombosis at high altitude.
abstract: Cerebral venous sinus thrombosis (CVST) is a rare but potentially life-threatening medical condition. We describe a case of a 47-year-old woman who presented with headache, speech defects, and visual disturbances, and was later diagnosed with cerebral venous sinus thrombosis. The article describes a possible risk of such thrombotic events with exposure to high altitude environment in patients with coagulation defects such as Factor V Leiden mutation. Besides, such neurological conditions can occur independent of altitude illness and need to be recognized as their management differs.
authors.affiliation: Nepal International Clinic, Travel and Mountain Medicine, Kathmandu, Nepal. promish610@yahoo.com
authors.forename: Promish
authors.initials: P
authors.lastname: Shrestha
authors.forename: Buddha
authors.initials: B
authors.lastname: Basnyat
authors.forename: Thomas
authors.initials: T
authors.lastname: Küpper
authors.forename: Simone
authors.initials: S
authors.lastname: van der Giet
mesh_terms: D000531:Altitude; D000925:Anticoagulants / Q000627:therapeutic use; D017984:Enoxaparin / Q000627:therapeutic use; D005165:Factor V / Q000235:genetics; D005260:Female; D006801:Humans; D008875:Middle Aged; D010644:Phenprocoumon / Q000627:therapeutic use; D011859:Radiography; D012851:Sinus Thrombosis, Intracranial / Q000150:complications* / Q000000981:diagnostic imaging / Q000188:drug therapy; D019851:Thrombophilia / Q000150:complications* / Q000235:genetics
chemical_list: D000925:Anticoagulants; D017984:Enoxaparin; C095381:factor V Leiden; D005165:Factor V; D010644:Phenprocoumon