title: [Metabolic syndrome and shift work: study of the relationship in workers of a chemical plant].
abstract: Metabolic syndrome is defined by several metabolic factors, related to one another, which induce atherosclerotic pathology. These factors are: visceral obesity, atherogenic dyslipidemia, high blood pressure, hyperglycemia, proinflammatory and prothrombotic state. Shift work is known to be related to a series of organic changes, including increased cardiovascular risk independent factors. The aim of our study is to assess if shift work might be a cofactor inducing metabolic syndrome. 119 workers of a chemical industry have been examinated and been divided in two groups: shift workers and daytime workers. We checked if workers were affected by metabolic syndrome, following the ATP III criteria. The results have been statistically compared. The prevalence of metabolic syndrome is significantly higher in night shift workers comparing to other workers. Among night shift workers metabolic syndrome was found in 28 out of 77 (36,36%); in daytime workers the syndrome was observed in 8 workers out of 42 (19,05%) (DR: 2, 43; 95% CI 0,99 - 5,98; p=0,049). This difference is stronger when only over 40 years old subjects were considered. Our results show an association between metabolic syndrome and night shift work. It is therefore necessary, as primary health safety measure, to verify the presence of metabolic syndrome in night shift workers. All aspects of the syndrome should be studied to prevent disease and its clinical complications. The primary prevention activity should be based on specific information and education programs, particulary aimed at learning about a correct lifestyle.
authors.affiliation: U.O. Medicina Ambientale e Medicina Occupazionale - IRCCS Fondazione Salvatore Maugeri, Pavia, Italy. giuseppe.taino@fsm.it
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Taino
authors.forename: Tiziana
authors.initials: T
authors.lastname: Gazzoldi
authors.forename: Marco
authors.initials: M
authors.lastname: Brevi
authors.forename: Marco
authors.initials: M
authors.lastname: Giorgi
authors.forename: Paola
authors.initials: P
authors.lastname: Imbriani
mesh_terms: D000328:Adult; D002617:Chemical Industry; D006801:Humans; D008297:Male; D024821:Metabolic Syndrome / Q000453:epidemiology*; D009784:Occupational Diseases / Q000453:epidemiology*; D015995:Prevalence; D014940:Work Schedule Tolerance