title: Two new antimicrobial flavanes from dragon's blood of Dracaena cambodiana.
abstract: Two new flavonoids, named cambodianins D (1) and E (2), together with two known flavanes (2S)-7,4'-dihydroxy-6,8-dimethylflavane (3) and (2S)-7,3'-dihydroxy-4'-methoxy-8-methylflavane (4), were isolated from dragon's blood of Dracaena cambodiana. The new compounds were determined by HR-ESI-MS and spectroscopic techniques (UV, IR, 1D, and 2D NMR). Compounds 1-3 exhibited antimicrobial activities.
authors.affiliation: Hainan Key Laboratory for Research and Development of Natural Products from Li Folk Medicine, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou, 571101, China.
authors.forename: Hui-Qin
authors.initials: HQ
authors.lastname: Chen
authors.forename: Wen-Jian
authors.initials: WJ
authors.lastname: Zuo
authors.forename: Hui
authors.initials: H
authors.lastname: Wang
authors.forename: Hai-Yan
authors.initials: HY
authors.lastname: Shen
authors.forename: Ying
authors.initials: Y
authors.lastname: Luo
authors.forename: Hao-Fu
authors.initials: HF
authors.lastname: Dai
authors.forename: Wen-Li
authors.initials: WL
authors.lastname: Mei
mesh_terms: D000890:Anti-Infective Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D031409:Dracaena / Q000737:chemistry*; D024881:Drug Resistance, Bacterial / Q000187:drug effects; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D005419:Flavonoids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D055624:Methicillin-Resistant Staphylococcus aureus / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010936:Plant Extracts / Q000737:chemistry*; D013211:Staphylococcus aureus / Q000187:drug effects
chemical_list: D000890:Anti-Infective Agents; D004365:Drugs, Chinese Herbal; D005419:Flavonoids; D010936:Plant Extracts; C573202:cambodianin D; C573203:cambodianin E; C525191:dragon's blood