title: A case of epididymitis associated with Panton-Valentine leukocidin Staphylococcus aureus.
abstract: A new pattern of disease caused by Panton-Valentine leukocidin (PVL)-positive strains of Staphylococcus aureus is emerging in the UK and worldwide. Community-associated methicillin-resistant S aureus (MRSA) is more likely to produce PVL, a pore-forming cytotoxin inducing leucocyte lysis, which often infects young healthy individuals. The worldwide emergence and continually increasing prevalence of community-acquired PVL-MRSA have recently attracted high-profile media attention and prompted concern regarding the transmissibility and virulence. This paper reports a case of genitourinary tract infection associated with PVL-positive community-associated MRSA in an immunocompetent young man.
authors.affiliation: Centre for Sexual Health, Scunthorpe General Hospital, Scunthorpe DN15 7BS, UK. malini.raychaudhuri@nhs.net
authors.forename: Malini
authors.initials: M
authors.lastname: Raychaudhuri
authors.forename: Pei Ru
authors.initials: PR
authors.lastname: Chew
mesh_terms: D000293:Adolescent; D001427:Bacterial Toxins / Q000235:genetics*; D017714:Community-Acquired Infections / Q000175:diagnosis / Q000382:microbiology / Q000473:pathology; D004269:DNA, Bacterial / Q000235:genetics; D004823:Epididymitis / Q000175:diagnosis* / Q000382:microbiology / Q000473:pathology*; D005098:Exotoxins / Q000235:genetics*; D006801:Humans; D007956:Leukocidins / Q000235:genetics*; D008297:Male; D055624:Methicillin-Resistant Staphylococcus aureus / Q000302:isolation & purification* / Q000472:pathogenicity; D016133:Polymerase Chain Reaction; D013203:Staphylococcal Infections / Q000175:diagnosis* / Q000382:microbiology / Q000473:pathology*; D006113:United Kingdom; D037521:Virulence Factors / Q000235:genetics*
chemical_list: D001427:Bacterial Toxins; D004269:DNA, Bacterial; D005098:Exotoxins; D007956:Leukocidins; C078284:Panton-Valentine leukocidin; D037521:Virulence Factors