title: Actinomyces cardiffensis septicemia: a case report.
abstract: Actinomyces cardiffensis is an anaerobic, Gram-positive, non-spore-forming rod that was first identified by Hall et al. (Hall V. et al. (2002) J Clin Microbiol 40:3427-31). Here we report a case of bacteremia with liver and lung abscesses associated with A. cardiffensis. A 67-year-old man was hospitalized with fever and headache for 20 days. Blood culture revealed an Actinomyces species, which was ultimately identified as A. cardiffensis by 16S rRNA gene sequencing. A computed tomography scan of his chest showed small abscesses in his lung and liver. After a 3-week course of intravenous ceftriaxone, the patient showed rapid improvement. The patient was transitioned to oral amoxicillin for the remainder of his antibiotic treatment.
authors.affiliation: Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea.
authors.forename: Jeong Youn
authors.initials: JY
authors.lastname: Seo
authors.forename: Joon-Sup
authors.initials: JS
authors.lastname: Yeom
authors.forename: Kwan Soo
authors.initials: KS
authors.lastname: Ko
mesh_terms: D000190:Actinomyces / Q000302:isolation & purification*; D000196:Actinomycosis / Q000175:diagnosis* / Q000382:microbiology / Q000473:pathology; D000284:Administration, Oral; D000368:Aged; D000658:Amoxicillin; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D001769:Blood / Q000382:microbiology; D002443:Ceftriaxone / Q000008:administration & dosage; D016000:Cluster Analysis; D004269:DNA, Bacterial / Q000737:chemistry / Q000235:genetics; D004275:DNA, Ribosomal / Q000737:chemistry / Q000235:genetics; D006760:Hospitalization; D006801:Humans; D007262:Infusions, Intravenous; D008100:Liver Abscess / Q000150:complications / Q000175:diagnosis / Q000382:microbiology / Q000473:pathology; D008169:Lung Abscess / Q000150:complications / Q000175:diagnosis / Q000382:microbiology / Q000473:pathology; D008297:Male; D010802:Phylogeny; D012336:RNA, Ribosomal, 16S / Q000235:genetics; D013902:Radiography, Thoracic; D018805:Sepsis / Q000150:complications / Q000175:diagnosis* / Q000382:microbiology / Q000473:pathology; D017422:Sequence Analysis, DNA; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D004269:DNA, Bacterial; D004275:DNA, Ribosomal; D012336:RNA, Ribosomal, 16S; D002443:Ceftriaxone; D000658:Amoxicillin