title: The next phase of life-sciences spaceflight research: Harnessing the power of functional genomics.
abstract: Recently we demonstrated that the effectiveness of RNAi interference (RNAi) for inhibiting gene expression is maintained during spaceflight in the worm Caenorhabditis elegans and argued for the biomedical importance of this finding. We also successfully utilized green fluorescent protein (GFP)-tagged proteins to monitor changes in GPF localization during flight. Here we discuss potential applications of RNAi and GFP in spaceflight studies and the ramifications of these experiments for the future of space life-sciences research.
authors.forename: Timothy
authors.initials: T
authors.lastname: Etheridge
authors.forename: Kanako
authors.initials: K
authors.lastname: Nemoto
authors.forename: Toko
authors.initials: T
authors.lastname: Hashizume
authors.forename: Chihiro
authors.initials: C
authors.lastname: Mori
authors.forename: Tomoko
authors.initials: T
authors.lastname: Sugimoto
authors.forename: Hiromi
authors.initials: H
authors.lastname: Suzuki
authors.forename: Keiji
authors.initials: K
authors.lastname: Fukui
authors.forename: Takashi
authors.initials: T
authors.lastname: Yamazaki
authors.forename: Akira
authors.initials: A
authors.lastname: Higashibata
authors.forename: Nathaniel J
authors.initials: NJ
authors.lastname: Szewczyk
authors.forename: Atsushi
authors.initials: A
authors.lastname: Higashitani