title: Phosphine-boronates: efficient bifunctional organocatalysts for Michael addition.
abstract: Phosphine-boronates R(2)P(o-C(6)H(4))B(OR')(2) have been evaluated as bifunctional organocatalysts for the Michael addition of malonate pronucleophiles to methylvinylketone. The presence of the Lewis acidic boron center adjacent to phosphorus significantly improves catalytic performance. Isolation and complete characterization of a key intermediate, namely a β-phosphonium enolate, substantiate the role of the Lewis acidic moiety in the catalytic process.
authors.affiliation: Université de Toulouse, UPS, LHFA, 118 route de Narbonne, F-31062 Toulouse, France.
authors.forename: Olivier
authors.initials: O
authors.lastname: Baslé
authors.forename: Susana
authors.initials: S
authors.lastname: Porcel
authors.forename: Sonia
authors.initials: S
authors.lastname: Ladeira
authors.forename: Ghenwa
authors.initials: G
authors.lastname: Bouhadir
authors.forename: Didier
authors.initials: D
authors.lastname: Bourissou