title: [Wheat dependent exercise induced anaphylaxis possibly sensitized by the hydrolyzed wheat proteins in a facial cleansing soap].
abstract: There are increasing cases of wheat dependent exercise-induced anaphylaxis (WDEIA) with transcutaneous or transmucosal sensitization. Hydrolyzed wheat included in a certain brand of soap was identified as a cause of sensitization. The useful clues to detect this disorder consist of the patient's past usage of a soap containing hydrolyzed wheat, the appearance of cutaneous or mucosal symptoms after the intake of wheat or washing with this soap, and a high level of specific IgE for wheat gluten. Because hydrolyzed wheat is used as an additive in a wide variety of cosmetics, we should pay careful attention to the ingredients of cosmetics when observing WDEIA.
authors.affiliation: Department of Dermatology, School of Medicine, University of Occupational and Environmental Health, Japan.
authors.forename: Miwa
authors.initials: M
authors.lastname: Kobayashi
authors.forename: Risa
authors.initials: R
authors.lastname: Okura
authors.forename: Haruna
authors.initials: H
authors.lastname: Yoshioka
authors.forename: Kana
authors.initials: K
authors.lastname: Hiromasa
authors.forename: Manabu
authors.initials: M
authors.lastname: Yoshioka
authors.forename: Motonobu
authors.initials: M
authors.lastname: Nakamura
mesh_terms: D000328:Adult; D000485:Allergens / Q000276:immunology*; D000707:Anaphylaxis / Q000276:immunology*; D015444:Exercise; D005260:Female; D006801:Humans; D006868:Hydrolysis; D010940:Plant Proteins / Q000276:immunology*; D012915:Soaps / Q000009:adverse effects*; D014908:Triticum / Q000276:immunology*; D021182:Wheat Hypersensitivity / Q000276:immunology*
chemical_list: D000485:Allergens; D010940:Plant Proteins; D012915:Soaps