title: Photo-controlled release of zinc metal ions by spiropyran receptors anchored to single-walled carbon nanotubes.
abstract: Light controllable release of antinflammatory zinc ions by a smart multifunctional material composed of spiropyrans and single walled carbon nanotubes (SWNTs) is demonstrated. The exploitation of a number of complementary characterization techniques allows the investigation of both composition and performance of the multifunctional SP/SWNT nanomaterial developed. Moreover, its suitability for potential applications in bio-systems is suggested by the effective removal of the metal catalyst and the introduction of biocompatible linkers into the SP/SWNT material. The realization of potential photo controllable SP/SWNTs based drug delivery systems (DDSs) is envisaged, where nanotubes act as intracellular carriers of light modulated receptors for bioactive agents.
authors.affiliation: School of Chemistry/Centre for Research on Adaptive Nanostructures and Nanodevices (CRANN), University of Dublin, Trinity College, Dublin 2, Ireland.
authors.forename: Elisa
authors.initials: E
authors.lastname: Del Canto
authors.forename: Manuel
authors.initials: M
authors.lastname: Natali
authors.forename: Dania
authors.initials: D
authors.lastname: Movia
authors.forename: Silvia
authors.initials: S
authors.lastname: Giordani
mesh_terms: D001578:Benzopyrans / Q000737:chemistry*; D045744:Cell Line, Tumor; D004337:Drug Carriers / Q000737:chemistry; D006801:Humans; D007211:Indoles / Q000737:chemistry*; D007477:Ions / Q000737:chemistry; D008027:Light; D037742:Nanotubes, Carbon / Q000737:chemistry*; D009574:Nitro Compounds / Q000737:chemistry*; D017550:Spectroscopy, Fourier Transform Infrared; D013059:Spectrum Analysis, Raman; D015032:Zinc / Q000737:chemistry*
chemical_list: D001578:Benzopyrans; D004337:Drug Carriers; D007211:Indoles; D007477:Ions; D037742:Nanotubes, Carbon; D009574:Nitro Compounds; C088184:spiropyran; D015032:Zinc