title: Copper-catalyzed azide-alkyne cycloaddition reaction in water using cyclodextrin as a phase transfer catalyst.
abstract: 1,4-Disubstituted-1,2,3-triazoles were obtained in excellent yields from azides and terminal alkynes in H(2)O in the presence of catalytic amount of β-cyclodextrin as a phase transfer catalyst. Also, a one-pot CuAAC reaction was carried out successfully, affording 1,4-disubstituted-1,2,3-triazoles in good to high yields starting from an alkyl bromide, sodium azide, and terminal alkyne.
authors.affiliation: 4-2, Agency for Defense Development, Yuseong, P.O. Box 35-4, 305-600 Daejeon, Republic of Korea.
authors.forename: Jung-Ah
authors.initials: JA
authors.lastname: Shin
authors.forename: Yeong-Gweon
authors.initials: YG
authors.lastname: Lim
authors.forename: Kyung-Hee
authors.initials: KH
authors.lastname: Lee