title: CT volumetry of normal pancreas: correlation with the pancreatic diameters measurable by the cross-sectional imaging, and relationship with the gender, age, and body constitution.
abstract: OBJECTIVE
  The purpose of this study was to estimate the volume of normal pancreas in adults using the CT volumetry (summation of the areas technique), analyze the correlation between the volume and the diameters of pancreas, which are measurable by the cross-sectional imaging, and assess the relationship with the gender, age, and body constitution.
  
  
  METHODS
  220 CT examinations were analyzed retrospectively (102 females, 118 males; age 16-82, average 56). Following diameters were measured: cranial-caudal-CC(pancreas), CC(body&tail), CC(body), CC(head); anterior-posterior--AP(tail), AP(body), AP(head); lengths--LL(head), L(body&tail); and maximal transversal diameter of the L1 vertebral body (LL(L1)) and thickness of the abdominal subcutaneous fat (AP(ASF)), as markers of body constitution.
  
  
  RESULTS
  The average volume of the pancreas was 79.2 ± 24.1 cm3 (ranging from 37.4 to 168.2 cm3). Pancreatic volume strongly correlated with all measured diameters of the pancreas (P < 0.0001). Pancreatic volume significantly correlated with gender (M:F = 86.1:72.8 cm3, P = 0.002) and the LL(L1) (r = 0.185, P = 0.008), and did not correlate with the age (r = -0.110, P = 0.151) and the AP(ASF) (r = -0.115, P = 0.104). Correlation of vertebral body-pancreas volume ratio of each subject and the age was strongly negative (r = -0.202, P = 0.006).
  
  
  CONCLUSIONS
  Marked individual variations in normal pancreas volume were observed. Pancreatic volume could be computed using the diameters measurable by the cross-sectional imaging employing the formula: V = (AP(tail) + AP(body))/2 × L(body&tail) × CC(body) + (AP(head)/2)2 × 3.14 × CC(head).
authors.affiliation: Unit of Digestive Radiology (First Surgical Clinic), Center of Radiology and MR, Clinical Center of Serbia, Koste Todorovica 6, 11000, Belgrade, Serbia. julijana.vuk@orion.rs
authors.forename: A
authors.initials: A
authors.lastname: Djuric-Stefanovic
authors.forename: D
authors.initials: D
authors.lastname: Masulovic
authors.forename: J
authors.initials: J
authors.lastname: Kostic
authors.forename: K
authors.initials: K
authors.lastname: Randjic
authors.forename: D
authors.initials: D
authors.lastname: Saranovic
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D001824:Body Constitution; D003287:Contrast Media; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009929:Organ Size; D010179:Pancreas / Q000033:anatomy & histology*; D012016:Reference Values; D012189:Retrospective Studies; D012737:Sex Factors; D054894:Spiral Cone-Beam Computed Tomography / Q000379:methods*; D055815:Young Adult
chemical_list: D003287:Contrast Media