title: [Improvement and estimation of tearscopy potentials].
abstract: New potentials of improved tearscopy technique based on photoregistration of colour interference phenomenon are presented. A new softwear "Lacrima" was developed in order to objectivate the results and to get more detailed data, it allows to reveal data on lipid layer thickness (LLT), estimate relative area of examined zone (in %) with certain LLT as well as regularity of lipids distribution. Digital images of interference picture of precorneal tear film of 13 healthy objects (26 eyes) and 20 patients with exogenous dry eye syndrome were analyzed. In eyes with dry eye syndrome compared to normal eyes increase of uncertainty zone and zone with minimal LLT were revealed for 13,2 and 12,8% respectively. Relative area of zones with increased LLT decreased for 16,7 and 56,3 % respectively. Computer analysis of interference picture of precorneal tear film using softwear "Lacrima" allows to extend capabilities of tearscopy and get additional data on lipid layer status.
authors.forename: G B
authors.initials: GB
authors.lastname: Egorova
authors.forename: I A
authors.initials: IA
authors.lastname: Novikov
authors.forename: T S
authors.initials: TS
authors.lastname: Mitichkina
mesh_terms: D000328:Adult; D015352:Dry Eye Syndromes / Q000175:diagnosis* / Q000000981:diagnostic imaging; D005123:Eye / Q000033:anatomy & histology; D005260:Female; D006801:Humans; D008055:Lipids / Q000032:analysis; D008875:Middle Aged; D013666:Tears / Q000737:chemistry*; D014463:Ultrasonography
chemical_list: D008055:Lipids