title: Propionibacterium acnes delayed infection following spinal surgery with instrumentation.
abstract: Propionibacterium acnes detection in culture media was previously considered a contamination but recently its infectious role was discovered in post-spinal surgery infections. P. acnes might be introduced during surgery. Its diagnosis is based on non-specific clinical signs, image indications of infection, and the conclusive microbiological sign. Furthermore, its diagnosis is difficult because of slow growth rate and low virulence, delaying its presentation. Usually, the infection is manifested after a couple of months or years. Here, a 65-year-old man presented with drainage at the site of instrumented spinal surgery performed 13 years ago. P. acnes infection was confirmed by culture with extended incubation. Our review of the literature revealed only two other reported cases of delayed P. acnes infection presenting a decade following a spinal surgery with instrumentation. This article sheds light on such delayed infections and discusses their presentation and management.
authors.affiliation: Department of Surgery, Hospital Universitario de Gran Canaria, Las Palmas, Spain.
authors.forename: Hani H
authors.initials: HH
authors.lastname: Mhaidli
authors.forename: Asdghig H
authors.initials: AH
authors.lastname: Der-Boghossian
authors.forename: Rachid K
authors.initials: RK
authors.lastname: Haidar
mesh_terms: D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002939:Ciprofloxacin / Q000627:therapeutic use; D057210:Delayed Diagnosis; D018450:Disease Progression; D005402:Fistula / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D005500:Follow-Up Studies; D016908:Gram-Positive Bacterial Infections / Q000150:complications* / Q000175:diagnosis / Q000382:microbiology / Q000628:therapy; D006801:Humans; D008297:Male; D019635:Neurosurgical Procedures / Q000009:adverse effects* / Q000379:methods; D011425:Propionibacterium acnes / Q000302:isolation & purification*; D016103:Spinal Fractures / Q000601:surgery*; D013530:Surgical Wound Infection / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D013904:Thoracic Vertebrae / Q000601:surgery; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D002939:Ciprofloxacin