title: Frontal lobe epilepsy with atypical seizure semiology resembling shuddering attacks or wet dog shake seizures.
abstract: We report a girl with a drug-resistant frontal lobe epilepsy caused by focal cortical dysplasia, who exhibited uncommon seizures. The seizures consisted of shoulder or whole body shuddering after a short psychic aura and face grimacing. Consciousness was fully preserved. The seizures resembled "wet dog shake" seizures described in rat models of epilepsy or shuddering attacks in infants. EEG findings were inconclusive, however, MRI showed a clear dysplastic lesion in the right frontal mesial and polar structures. The patient underwent an extended lesionectomy guided by neuronavigation and intraoperative electrocorticography. Focal cortical dysplasia type Ib was histologically confirmed and the patient has been seizure-free for the three years following resection. [Published with video sequences].
authors.affiliation: Department of Pediatric Neurology, Motol Epilepsy Centre, Charles University, 2nd Medical School, Motol Hospital, Prague, Czech Republic.
authors.forename: Alena
authors.initials: A
authors.lastname: Jahodova
authors.forename: Pavel
authors.initials: P
authors.lastname: Krsek
authors.forename: Vladimir
authors.initials: V
authors.lastname: Komarek
authors.forename: Martin
authors.initials: M
authors.lastname: Kudr
authors.forename: Martin
authors.initials: M
authors.lastname: Kyncl
authors.forename: Josef
authors.initials: J
authors.lastname: Zamecnik
authors.forename: Michal
authors.initials: M
authors.lastname: Tichy
mesh_terms: D002648:Child; D004569:Electroencephalography; D017034:Epilepsy, Frontal Lobe / Q000473:pathology / Q000503:physiopathology* / Q000601:surgery; D005260:Female; D005625:Frontal Lobe / Q000473:pathology / Q000503:physiopathology* / Q000601:surgery; D006801:Humans; D054220:Malformations of Cortical Development / Q000473:pathology / Q000503:physiopathology* / Q000601:surgery; D019635:Neurosurgical Procedures; D012640:Seizures / Q000473:pathology / Q000503:physiopathology* / Q000601:surgery; D016896:Treatment Outcome