title: Ocular complications of malaria treatment.
abstract: Malaria is endemic in Nigeria. With the emergence of chloroquine resistance various modes of treatment including parenteral quinine are employed with consequent untoward effects. This article reports two cases of severe ocular toxicity, including mimicry of intracranial space-occupying lesion, from treatment of malaria with various drugs including quinine. Medical practitioners are advised to exhaust other less toxic modes of therapy before using drugs with great potential for severe untoward effects such as quinine.
authors.affiliation: Guinness Eye Center, Onitsha, Nigeria. nwoseb@hotmail.com
authors.forename: Snn
authors.initials: S
authors.lastname: Nwosu
mesh_terms: D000284:Administration, Oral; D000328:Adult; D000962:Antimalarials / Q000009:adverse effects* / Q000627:therapeutic use; D005128:Eye Diseases / Q000139:chemically induced / Q000150:complications*; D005260:Female; D006801:Humans; D016778:Malaria, Falciparum / Q000175:diagnosis / Q000188:drug therapy*; D009549:Nigeria; D010963:Plasmodium falciparum / Q000302:isolation & purification; D011239:Prednisolone / Q000008:administration & dosage; D011803:Quinine / Q000009:adverse effects* / Q000627:therapeutic use; D014785:Vision, Ocular / Q000187:drug effects*
chemical_list: D000962:Antimalarials; D011239:Prednisolone; D011803:Quinine