title: Gorham-Stout disease and cerebrospinal fluid otorrhea.
abstract: OBJECTIVE
  Gorham-Stout disease is a rare entity characterized by vascular proliferation causing local destruction of bone tissue. Owing to its low incidence and variable clinical presentation, the diagnosis requires a high degree of awareness by the clinician.
  
  
  METHODS
  We present the case of a 2-year-old boy diagnosed of Gorham-Stout syndrome with involvement of the temporal bone and secondary cerebrospinal fluid (CSF) leakage.
  
  
  METHODS
  Because of the CSF leakage, the patient required two surgical interventions. The second intervention included mastectomy and placement of a patch and a lumbar drainage device during 50 days, after which the leakage ceased.
  
  
  CONCLUSIONS
  Gorham-Stout disease is a rare condition that can affect the skull base and even present with CSF leakage.
authors.affiliation: Department of Pediatric Hematology-Oncology, Hospital Infantil Universitario Niño Jesús, Madrid, Spain. chmtl@hotmail.com
authors.forename: Carmen
authors.initials: C
authors.lastname: Hernández-Marqués
authors.forename: Ana
authors.initials: A
authors.lastname: Serrano González
authors.forename: Francisco
authors.initials: F
authors.lastname: Cordobés Ortega
authors.forename: Javier
authors.initials: J
authors.lastname: Alvarez-Coca
authors.forename: Sara
authors.initials: S
authors.lastname: Sirvent Cerda
authors.forename: Fernando
authors.initials: F
authors.lastname: Carceller Lechón
authors.forename: Daniel
authors.initials: D
authors.lastname: Azorín Cuadrillero
mesh_terms: D002558:Cerebrospinal Fluid Otorrhea / Q000209:etiology / Q000601:surgery*; D002675:Child, Preschool; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D010015:Osteolysis, Essential / Q000134:cerebrospinal fluid / Q000150:complications / Q000601:surgery*; D013506:Otologic Surgical Procedures / Q000379:methods*; D014057:Tomography, X-Ray Computed