title: MR imaging findings of the intraspinal meningeal melanocytoma: correlation with histopathologic findings.
abstract: Our aim was to better understand and improve the accuracy of the preoperative diagnosis of intraspinal MM by a combined analysis of MR imaging and pathologic findings. All 5 patients had undergone unenhanced and contrast-enhanced MR imaging examinations. All tumor samples had immunohistochemical reactions to HMB-45, vimentin, S-100, EMA, and Leu-7 antibodies. All 5 cases were located in the intradural extramedullary compartment. Two cases had multifocal lesions, and 3 cases were solitary. Two cases showed homogeneously strong enhancement, and 3 cases showed moderate enhancement on contrast-enhanced T1WI. The tumor cells had positive reactions to HMB-45, vimentin, and S-100 antibodies. MR imaging plays an important role in the detection and diagnosis of intraspinal MM. Final diagnosis should be based on histopathology and IHC examinations.
authors.affiliation: Department of Medical Image Center, Nanshan Hospital, Guangdong Medical College, Guangdong Province, People's Republic of China.
authors.forename: G Q
authors.initials: GQ
authors.lastname: Hou
authors.forename: J C
authors.initials: JC
authors.lastname: Sun
authors.forename: X J
authors.initials: XJ
authors.lastname: Zhang
authors.forename: B X
authors.initials: BX
authors.lastname: Shen
authors.forename: X J
authors.initials: XJ
authors.lastname: Zhu
authors.forename: L
authors.initials: L
authors.lastname: Liang
authors.forename: X L
authors.initials: XL
authors.lastname: Zhang
mesh_terms: D003287:Contrast Media; D005260:Female; D019786:Gadolinium DTPA; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008545:Melanoma / Q000473:pathology* / Q000601:surgery; D008577:Meningeal Neoplasms / Q000473:pathology* / Q000601:surgery; D008875:Middle Aged; D013120:Spinal Cord Neoplasms / Q000473:pathology* / Q000601:surgery
chemical_list: D003287:Contrast Media; D019786:Gadolinium DTPA