title: Hypohidrotic (anhidrotic) ectodermal dysplasia in female twins.
abstract: Autosomal recessive hereditary ectodermal dysplasia (HED) has not been described in sub-Saharan Africa. It is acknowledged to be rarer than the occasionally reported x-linked and autosomal dominant variants. We report a pair of Nigerian female twins with family history and clinical features suggestive of recessive HED, thereby showing the existence of this rare form in sub-Saharan Africa.
authors.affiliation: Department of Paediatrics, Ahmadu Bello University Teaching Hospital, Zaria, Nigeria. femiogunrinde@hotmail.com
authors.forename: G O
authors.initials: GO
authors.lastname: Ogunrinde
authors.forename: R O
authors.initials: RO
authors.lastname: Zubair
authors.forename: S O
authors.initials: SO
authors.lastname: Ajike
authors.forename: S O
authors.initials: SO
authors.lastname: Ige
mesh_terms: D000505:Alopecia / Q000235:genetics*; D000848:Anodontia / Q000235:genetics*; D002675:Child, Preschool; D004476:Ectodermal Dysplasia / Q000235:genetics*; D005260:Female; D050172:Genes, X-Linked; D006801:Humans; D007007:Hypohidrosis / Q000235:genetics*; D010375:Pedigree; D012867:Skin / Q000473:pathology; D013545:Sweat Glands / Q000002:abnormalities