title: Prevalence and genotype distribution of human papillomavirus infection among female sex workers in Guangxi, China: implications for interventions.
abstract: Human papillomavirus (HPV) infection is a major public health concern in women, but information on HPV among female sex workers in China is limited. The aim of the study was to estimate the prevalence and genotype distribution of HPV infection among female sex workers in two cities in Guangxi, China. A total of 811 female sex workers were recruited from venues between July and September of 2009. Data on socio-demographic and behavior characteristics were collected, and cervical swabs were collected to determine HPV infection and genotype distribution. The overall prevalence of infection with any HPV type was 38.9%. HPV type 52 was the most prevalent type with prevalence of 11%, followed by HPV types 16, 58, 53, and CP8304, with prevalences of 6.5%, 5.7%, 5.6%, and 4.8%, respectively. HPV 16 or 18 accounted for 23.2% of all HPV positive cases. Age group <20 years was significantly associated with infection of the high-risk and multiple types of HPV infection. A higher prevalence of multiple HPV infection was observed among female sex workers from the outdoor venues (14.0%; 95%CI, 10.6%-17.3%). These findings have important implications for developing HPV prevention programs including HPV vaccination in female sex workers.
authors.affiliation: Chinese Academy of Medical Sciences and Peking Union Medical College Institute of Dermatology, Nanjing, China.
authors.forename: Hong-Min
authors.initials: HM
authors.lastname: Li
authors.forename: Guo-Jun
authors.initials: GJ
authors.lastname: Liang
authors.forename: Yue-Ping
authors.initials: YP
authors.lastname: Yin
authors.forename: Qian-Qiu
authors.initials: QQ
authors.lastname: Wang
authors.forename: Zhi-Ju
authors.initials: ZJ
authors.lastname: Zheng
authors.forename: Ju-Jiao
authors.initials: JJ
authors.lastname: Zhou
authors.forename: Ning
authors.initials: N
authors.lastname: Jiang
authors.forename: Guang-Jie
authors.initials: GJ
authors.lastname: Tan
authors.forename: Baoxi
authors.initials: B
authors.lastname: Wang
authors.forename: Xiang-Sheng
authors.initials: XS
authors.lastname: Chen
mesh_terms: D000293:Adolescent; D000328:Adult; D002681:China / Q000453:epidemiology; D004279:DNA, Viral / Q000235:genetics; D005260:Female; D005838:Genotype; D006801:Humans; D008875:Middle Aged; D027383:Papillomaviridae / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D030361:Papillomavirus Infections / Q000453:epidemiology* / Q000517:prevention & control / Q000821:virology; D015995:Prevalence; D016730:Program Development; D060386:Sex Workers / Q000706:statistics & numerical data; D055815:Young Adult
chemical_list: D004279:DNA, Viral