title: [Effects of hops on ovariectomized obese rats].
abstract: OBJECTIVE
  To investigate the effects of hops on obesity in ovariectomy rats. MEHTODS: After ablating bilateral ovarian, adult Sprague-Dawley rats were drinken water extracts of hops and its effects on body weight were observed. On the seventh weekend, blood was collected to assay serum free fat acid (FFA), total anti-oxidative capacity (T-AOC), malondialdehyde (MDA), estrogen, testosterone and insulin.
  
  
  RESULTS
  Compared with SHAM group, rats in OVX group displayed the higher weight, serum FFA, MDA and levels of insulin, lower serum levels of estrogen and testosterone and T-AOC. After drinken water extracts of hops, compared with OVX group, rats in OVX + hops group had lower weight, serum FFA, MDA, levels of insulin and higher serum T-AOC.
  
  
  CONCLUSIONS
  Hops could promote weight loss in OVX rats. Hops maybe have estrogen activity. It can increase sensibitity of insulin and elevate anti-oxidative capacity.
authors.affiliation: Lanzhou Medical College, Lanzhou 730000.
authors.forename: Jiangbi
authors.initials: J
authors.lastname: Wang
authors.forename: Rong
authors.initials: R
authors.lastname: Luo
authors.forename: Xuesong
authors.initials: X
authors.lastname: Tian
authors.forename: Yonghui
authors.initials: Y
authors.lastname: Ding
authors.forename: Songyi
authors.initials: S
authors.lastname: Qu
authors.forename: Wei
authors.initials: W
authors.lastname: Li
authors.forename: Tianzhen
authors.initials: T
authors.lastname: Zheng
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000302:isolation & purification / Q000494:pharmacology; D001835:Body Weight / Q000187:drug effects*; D004195:Disease Models, Animal; D004365:Drugs, Chinese Herbal / Q000302:isolation & purification / Q000494:pharmacology*; D004967:Estrogens / Q000097:blood; D005230:Fatty Acids, Nonesterified / Q000097:blood; D005260:Female; D035264:Flowers / Q000737:chemistry; D027582:Humulus / Q000737:chemistry*; D007328:Insulin / Q000097:blood; D009765:Obesity / Q000097:blood / Q000517:prevention & control*; D010052:Ovariectomy; D011897:Random Allocation; D051381:Rats; D017207:Rats, Sprague-Dawley
chemical_list: D000975:Antioxidants; D004365:Drugs, Chinese Herbal; D004967:Estrogens; D005230:Fatty Acids, Nonesterified; D007328:Insulin