title: PRIDE: quality control in a proteomics data repository.
abstract: The PRoteomics IDEntifications (PRIDE) database is a large public proteomics data repository, containing over 270 million mass spectra (by November 2011). PRIDE is an archival database, providing the proteomics data supporting specific scientific publications in a computationally accessible manner. While PRIDE faces rapid increases in data deposition size as well as number of depositions, the major challenge is to ensure a high quality of data depositions in the context of highly diverse proteomics work flows and data representations. Here, we describe the PRIDE curation pipeline and its practical application in quality control of complex data depositions. DATABASE URL: http://www.ebi.ac.uk/pride/.
authors.affiliation: EMBL Outstation, European Bioinformatics Institute (EBI), Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SD, UK. acsordas@ebi.ac.uk.
authors.forename: Attila
authors.initials: A
authors.lastname: Csordas
authors.forename: David
authors.initials: D
authors.lastname: Ovelleiro
authors.forename: Rui
authors.initials: R
authors.lastname: Wang
authors.forename: Joseph M
authors.initials: JM
authors.lastname: Foster
authors.forename: Daniel
authors.initials: D
authors.lastname: Ríos
authors.forename: Juan Antonio
authors.initials: JA
authors.lastname: Vizcaíno
authors.forename: Henning
authors.initials: H
authors.lastname: Hermjakob
mesh_terms: D003628:Database Management Systems / Q000592:standards*; D030562:Databases, Protein / Q000592:standards*; D006801:Humans; D013058:Mass Spectrometry; D011506:Proteins / Q000737:chemistry* / Q000145:classification; D040901:Proteomics / Q000379:methods* / Q000592:standards*; D011786:Quality Control
chemical_list: D011506:Proteins