title: A novel case of concurrent renal tumors: chromophobe renal cell carcinoma and carcinoid tumor of the kidney with brief review of renal neuroendocrine tumors.
abstract: Renal cell carcinoma of chromophobe type is a malignant neoplasm with characteristic large cells that exhibit prominent cell membranes. Primary renal carcinoid tumors are rare tumors with the histological appearance similar to well-differentiated neuroendocrine tumors at other sites. Chromophobe renal cell carcinoma with neuroendocrine differentiation is exceedingly rare. The authors describe a case of a chromophobe renal cell carcinoma and carcinoid tumor of the kidney presenting as distinct masses in the same kidney in a 34-year-old male. The histologic and immunohistochemical features of both the tumors were characteristic with no overlapping features. The carcinoid tumor presented at a higher stage with nodal metastasis. To the best of the authors' knowledge, this is the first case of 2 morphologically distinct tumors, one chromophobe renal cell carcinoma and the other primary carcinoid tumor in the same kidney.
authors.affiliation: Department of Pathology, University of Pittsburgh, Pittsburgh, PA 15261, USA. roys911@gmail.com
authors.forename: Somak
authors.initials: S
authors.lastname: Roy
authors.forename: Shveta
authors.initials: S
authors.lastname: Hooda
authors.forename: George J
authors.initials: GJ
authors.lastname: Huang
authors.forename: Liron
authors.initials: L
authors.lastname: Pantanowitz
authors.forename: Anil V
authors.initials: AV
authors.lastname: Parwani
mesh_terms: D000328:Adult; D002276:Carcinoid Tumor / Q000473:pathology*; D002292:Carcinoma, Renal Cell / Q000473:pathology*; D049109:Cell Proliferation; D006801:Humans; D007680:Kidney Neoplasms / Q000473:pathology*; D008198:Lymph Nodes / Q000473:pathology; D008297:Male; D009367:Neoplasm Staging; D009378:Neoplasms, Multiple Primary