title: [Resection of petrous apex cholesteatoma via endoscopic trans-sphenoidal approach].
abstract: OBJECTIVE
  To introduce our experience of resection of petrous apex cholesteatoma through endoscopic, transnasal, trans-sphenoidal approach in 3 cases, and present a surgical technique of intracystic resection of lesion which yielded a relatively stable long-term outcome.
  
  
  METHODS
  Resection of parasellar and petrous apex cholesteatoma via endoscopic transsphenoidal approach was performed in three patients between 2001 and 2006. Surgical technique was as follows: the ethmoid and sphenoid sinuses were opened under endoscope, the petrous apex was accessed by drilling skull base bone at the lateral wall of sphenoid sinus and anterior to the internal carotid artery, the cyst wall of cholesteatoma was incised and expanded, then intracystic removal of cholesteatoma was achieved by the suction, curette and rinsing.
  
  
  RESULTS
  The petrous apex cholesteatoma in all 3 patients were removed clearly by endoscopic, transnasal, trans-sphenoidal surgery in one time. Before surgery, two patients with headache and orbital apex syndrome had a remarkable improvement just on the day after operation and completely recovered in 1-4 weeks. No postoperative complications happened in all three patients. All patients had no recurrence in symptoms and no imaging evidences of recurrence at a follow-up of 3 - 7 years.
  
  
  CONCLUSIONS
  The petrous apex cholesteatoma around the parasellar region could be treated by intracystic removal via endoscopic, transnasal, transsphenoidal approach, without the need to strip and remove the cyst wall, and the long-term efficacy was reliable.
authors.affiliation: Hospital of Otorhinolaryngology, First Affiliated Hospital of SUN Yat-sen University, Guangzhou 510080, China.
authors.forename: Rui
authors.initials: R
authors.lastname: Xu
authors.forename: Qiu-hang
authors.initials: QH
authors.lastname: Zhang
authors.forename: Ke-jun
authors.initials: KJ
authors.lastname: Zuo
authors.forename: Geng
authors.initials: G
authors.lastname: Xu
mesh_terms: D000328:Adult; D000368:Aged; D002781:Cholesteatoma / Q000601:surgery*; D004724:Endoscopy; D006801:Humans; D008297:Male; D019291:Skull Base / Q000601:surgery; D013101:Sphenoid Sinus / Q000601:surgery*; D055815:Young Adult