title: Nonconvulsive status epilepticus due to drug induced neurotoxicity in chronically ill children.
abstract: Nonconvulsive status epilepticus (NCSE) is a specific form of status epilepticus and is defined as epileptic activity on an EEG without seizures and as an alteration in mental status lasting more than 30 min. NCSE may be caused by drugs, cerebrovascular events, metabolic disorders or toxins. Herein, we present four cases of patients with drug-induced NCSE who were chronically ill due to renal failure or childhood leukemia. NCSE should be suspected in patients with an altered mental status without clinical seizures who are being treated with multiple drugs.
authors.affiliation: Department of Pediatric Neurology, Osmangazi University Medicine Faculty, Eskisehir, Turkey. drarzuekici@gmail.com
authors.forename: Arzu
authors.initials: A
authors.lastname: Ekici
authors.forename: Ayten
authors.initials: A
authors.lastname: Yakut
authors.forename: Nurdan
authors.initials: N
authors.lastname: Kural
authors.forename: Özcan
authors.initials: Ö
authors.lastname: Bör
authors.forename: Sevgi
authors.initials: S
authors.lastname: Yimenicioğlu
authors.forename: Kürşat Bora
authors.initials: KB
authors.lastname: Çarman
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D004569:Electroencephalography; D005260:Female; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000188:drug therapy; D008297:Male; D020258:Neurotoxicity Syndromes / Q000188:drug therapy*; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000188:drug therapy; D051437:Renal Insufficiency / Q000188:drug therapy; D013226:Status Epilepticus / Q000139:chemically induced* / Q000175:diagnosis / Q000188:drug therapy*; D016896:Treatment Outcome