title: Basal cell carcinoma in skin of color.
abstract: Non-melanoma skin cancer most commonly affects Caucasians, and only rarely affects darker-skinned individuals. However, skin cancer in these groups is associated with greater morbidity and mortality. Ultraviolet radiation is the major etiologic factor in basal cell carcinoma (BCC) and likely plays a pivotal role in the development of other forms of skin cancer. Yet it is commonly thought among patients as well as physicians that darker pigmentation inherently affords complete protection from skin cancer development. This low index of suspicion results in delayed diagnoses and poorer outcomes. This review follows a detailed computer search that cross-matched the diagnosis of BCC with skin color type in a large commercial dermatopathology facility. The reported skin types, all Fitzpatrick skin types IV, V, and VI, and histories were confirmed. A predominance of pigmented BCCs was found in sun-exposed areas of these older individuals. Although less common in darker-skinned ethnic groups, BCC does occur and can pose significant morbidity. Thus, it is essential that dermatologists are familiar with the epidemiology and clinical presentation of all cutaneous malignancies in darker skin so that these patients are fully aware of risks as well as prevention of the disease.
authors.affiliation: Wayne State University Department of Dermatology Detroit, MI, USA. jahluwal@med.wayne.edu
authors.forename: Jesleen
authors.initials: J
authors.lastname: Ahluwalia
authors.forename: Elena
authors.initials: E
authors.lastname: Hadjicharalambous
authors.forename: Darius
authors.initials: D
authors.lastname: Mehregan
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D002280:Basal Cell Carcinoma / Q000453:epidemiology / Q000208:ethnology / Q000473:pathology; D012878:Skin Neoplasms / Q000453:epidemiology / Q000208:ethnology / Q000473:pathology; D013472:Sunlight / Q000009:adverse effects; D000091762:Ethnic and Racial Minorities