title: [A case of Bellini collecting duct carcinoma with hypercalcemia in a young adult].
abstract: A 25-year-old man presented to a local clinic with right flank pain and gross hematuria. Computed tomography revealed the right renal tumor and he was referred to our hospital. Laparoscopic radical nephrectomy was performed and diagnosis of Bellini collecting duct carcinoma was made pathologically. Adjuvant therapy with interferon-α, followed by a gemcitabine and cisplatin-based regimen of chemotherapy was performed, but the disease progressed. Sunitinib was started 14 months after the operation. After one course of sunitinib, mental status was altered due to hypercalcemia (serum calcium level was 18.6 mg/dl and PTH-rP was 3.7 pmol/l). Level of consciousness recovered along with decreasing serum calcium level, but he died of multiple organ dysfunction 17 months after the operation. Autopsy showed liver, bone, lymph node, mediastinum and left adrenal tumor metastases.
authors.affiliation: The Department of Urology, Kobe City Medical Center General Hospital.
authors.forename: Yoshiho
authors.initials: Y
authors.lastname: Kamimura
authors.forename: Takehiko
authors.initials: T
authors.lastname: Segawa
authors.forename: Norihiko
authors.initials: N
authors.lastname: Masuda
authors.forename: Noriaki
authors.initials: N
authors.lastname: Utsunomiya
authors.forename: Koei
authors.initials: K
authors.lastname: Muguruma
authors.forename: Mutsushi
authors.initials: M
authors.lastname: Kawakita
mesh_terms: D000328:Adult; D002292:Carcinoma, Renal Cell / Q000473:pathology* / Q000628:therapy; D003131:Combined Modality Therapy; D006801:Humans; D006934:Hypercalcemia / Q000150:complications*; D007680:Kidney Neoplasms / Q000473:pathology* / Q000628:therapy; D008297:Male; D009392:Nephrectomy