title: Synthesis and structural determination of novel 5-arylidene-3-N(2-alkyloxyaryl)-2-thioxothiazolidin-4-ones.
abstract: As part of our project devoted to the synthesis of heterocycles including thiazole rings, some new 5-arylidene-2-thioxo-3-N-arylthiazolidin-4-ones were synthesized by Knoevenagel condensation. An interesting feature of these compounds is that their chirality is induced by that of their 3-N-(2-alkyloxyaryl)-2-thioxothiazolidin-4-one precursors, which in turn is due to the presence of a C2 axis of chirality. These new compounds were characterized by spectroscopic methods (IR, 1H-NMR, 13C-NMR). The structure of compound (Z)-(2g) was further determined by X-ray diffraction.
authors.affiliation: Laboratoire de Synthèse Organique Appliquée, BP 1524, El Menaouer, Université d'Oran Es-Senia, 31000 Oran, Algérie.
authors.forename: Khaled
authors.initials: K
authors.lastname: Toubal
authors.forename: Ayada
authors.initials: A
authors.lastname: Djafri
authors.forename: Abdelkader
authors.initials: A
authors.lastname: Chouaih
authors.forename: Abdou
authors.initials: A
authors.lastname: Talbi
mesh_terms: D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D013844:Thiazoles / Q000138:chemical synthesis* / Q000737:chemistry*; D014961:X-Ray Diffraction
chemical_list: D013844:Thiazoles