title: Mice guide human drug trial.
authors.forename: Heidi
authors.initials: H
authors.lastname: Ledford
mesh_terms: D055372:AMP-Activated Protein Kinases; D000818:Animals; D001562:Benzimidazoles / Q000494:pharmacology / Q000627:therapeutic use; D002986:Clinical Trials as Topic / Q000379:methods* / Q000639:trends; D004195:Disease Models, Animal; D019008:Drug Resistance, Neoplasm / Q000235:genetics; D016158:Genes, p53 / Q000235:genetics; D006801:Humans; D051379:Mice; D009369:Neoplasms / Q000175:diagnosis / Q000188:drug therapy / Q000235:genetics; D049268:Positron-Emission Tomography; D017346:Protein Serine-Threonine Kinases / Q000235:genetics; D011518:Proto-Oncogene Proteins / Q000235:genetics; D016283:Proto-Oncogene Proteins p21(ras) / Q000235:genetics; D018631:ras Proteins / Q000235:genetics
chemical_list: C517975:AZD 6244; D001562:Benzimidazoles; C117307:KRAS protein, human; D011518:Proto-Oncogene Proteins; D017346:Protein Serine-Threonine Kinases; C491654:Stk11 protein, mouse; D055372:AMP-Activated Protein Kinases; C495971:Hras protein, mouse; D016283:Proto-Oncogene Proteins p21(ras); D018631:ras Proteins