title: Synthesis of [(4-chloro-5H-1,2,3-dithiazol-5-ylidene)amino]azines.
abstract: The reactions of 2-, 3- and 4-aminopyridines with 4,5-dichloro-1,2,3-dithiazolium chloride (Appel salt) 4 to give N-(4-chloro-5H-1,2,3-dithiazol-5-ylidene)pyridin-X-amines 1a (X = 2), 1g (X = 3) and 1k (X = 4) were optimized with respect to base, temperature and reaction time. Based on these conditions a total of thirteen [(dithiazolylidene)amino]azines 1a-m were prepared and fully characterized.
authors.affiliation: Department of Chemistry, University of Cyprus, P.O. Box 20537, 1678 Nicosia, Cyprus. koutenti@ucy.ac.cy
authors.forename: Panayiotis A
authors.initials: PA
authors.lastname: Koutentis
authors.forename: Maria
authors.initials: M
authors.lastname: Koyioni
authors.forename: Sophia S
authors.initials: SS
authors.lastname: Michaelidou
mesh_terms: D000631:Aminopyridines / Q000737:chemistry*; D055598:Chemical Phenomena; D006834:Hydrazines / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D013696:Temperature; D013844:Thiazoles / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: C570987:4,5-dichloro-1,2,3-dithiazolium chloride; D000631:Aminopyridines; D006834:Hydrazines; D013844:Thiazoles