title: Reactive intermediates-induced potential responses of a polymeric membrane electrode for ultrasensitive potentiometric biosensing.
abstract: Reactive intermediates rather than stable reactants or products have been found to induce large potential responses on an appropriately formulated polymeric membrane electrode, which provides a novel methodology for ultrasensitive potentiometric biosensing based on the horseradish peroxidase-H(2)O(2) oxidation reaction.
authors.affiliation: Key Laboratory of Coastal Zone Environmental Processes, Yantai Institute of Coastal Zone Research (YIC), Chinese Academy of Sciences (CAS), YICCAS, Yantai, 264003, PR China.
authors.forename: Xuewei
authors.initials: X
authors.lastname: Wang
authors.forename: Wei
authors.initials: W
authors.lastname: Qin
mesh_terms: D000328:Adult; D015374:Biosensing Techniques / Q000379:methods*; D001786:Blood Glucose / Q000032:analysis* / Q000378:metabolism; D004566:Electrodes; D004800:Enzymes, Immobilized / Q000378:metabolism; D006735:Horseradish Peroxidase / Q000378:metabolism; D006801:Humans; D006861:Hydrogen Peroxide / Q000032:analysis* / Q000378:metabolism; D010084:Oxidation-Reduction; D011108:Polymers / Q000737:chemistry*; D011199:Potentiometry / Q000379:methods*; D012680:Sensitivity and Specificity
chemical_list: D001786:Blood Glucose; D004800:Enzymes, Immobilized; D011108:Polymers; D006861:Hydrogen Peroxide; D006735:Horseradish Peroxidase