title: Covariation of learning and "reasoning" abilities in mice: evolutionary conservation of the operations of intelligence.
abstract: Contemporary descriptions of human intelligence hold that this trait influences a broad range of cognitive abilities, including learning, attention, and reasoning. Like humans, individual genetically heterogeneous mice express a "general" cognitive trait that influences performance across a diverse array of learning and attentional tasks, and it has been suggested that this trait is qualitatively and structurally analogous to general intelligence in humans. However, the hallmark of human intelligence is the ability to use various forms of "reasoning" to support solutions to novel problems. Here, we find that genetically heterogeneous mice are capable of solving problems that are nominally indicative of inductive and deductive forms of reasoning, and that individuals' capacity for reasoning covaries with more general learning abilities. Mice were characterized for their general learning ability as determined by their aggregate performance (derived from principal component analysis) across a battery of five diverse learning tasks. These animals were then assessed on prototypic tests indicative of deductive reasoning (inferring the meaning of a novel item by exclusion, i.e., "fast mapping") and inductive reasoning (execution of an efficient search strategy in a binary decision tree). The animals exhibited systematic abilities on each of these nominal reasoning tasks that were predicted by their aggregate performance on the battery of learning tasks. These results suggest that the coregulation of reasoning and general learning performance in genetically heterogeneous mice form a core cognitive trait that is analogous to human intelligence.
authors.affiliation: Department of Psychology, Program in Behavioral Neuroscience, Rutgers University, Piscataway, NJ 08854, USA.
authors.forename: Christopher
authors.initials: C
authors.lastname: Wass
authors.forename: Alexander
authors.initials: A
authors.lastname: Denman-Brice
authors.forename: Chris
authors.initials: C
authors.lastname: Rios
authors.forename: Kenneth R
authors.initials: KR
authors.lastname: Light
authors.forename: Stefan
authors.initials: S
authors.lastname: Kolata
authors.forename: Andrew M
authors.initials: AM
authors.lastname: Smith
authors.forename: Louis D
authors.initials: LD
authors.lastname: Matzel
mesh_terms: D000818:Animals; D001245:Association Learning; D001362:Avoidance Learning; D001522:Behavior, Animal / Q000502:physiology*; D003210:Concept Formation / Q000502:physiology*; D003213:Conditioning, Psychological; D003657:Decision Making / Q000502:physiology*; D004193:Discrimination Learning / Q000502:physiology; D005106:Exploratory Behavior / Q000502:physiology; D005239:Fear / Q000523:psychology; D005508:Food Deprivation / Q000502:physiology; D007858:Learning / Q000145:classification / Q000502:physiology*; D008297:Male; D018782:Maze Learning; D051379:Mice; D009812:Odorants; D025341:Principal Component Analysis