title: Multicentric neurofibromatosis with rectal prolapse in a California sea lion (Zalophus californianus).
abstract: An approximately 31-yr-old California sea lion (Zalophus californianus) with a history of chronic visual impairment and corneal disease presented with slow onset, progressive neurologic deficits. Treatment for rear flipper paresis was not effective and the animal was euthanatized. Histopathologic findings included hepatocellular and biliary neoplasia, ocular amyloidosis, adrenal adenoma and pheochromocytoma, and spinal cord changes consistent with multicentric neurofibromatosis. This is the first documentation of these conditions in a California sea lion.
authors.affiliation: Department of Veterinary Services, Birmingham Zoo, Inc., 2630 Cahaba Road, Birmingham, Alabama 35226, USA. zuvet9@yahoo.com
authors.forename: Elizabeth M
authors.initials: EM
authors.lastname: Rush
authors.forename: Anna L
authors.initials: AL
authors.lastname: Ogburn
authors.forename: Michael M
authors.initials: MM
authors.lastname: Garner
mesh_terms: D000310:Adrenal Gland Neoplasms / Q000473:pathology / Q000662:veterinary; D000686:Amyloidosis / Q000473:pathology / Q000662:veterinary; D000818:Animals; D005128:Eye Diseases / Q000473:pathology / Q000662:veterinary; D005260:Female; D009378:Neoplasms, Multiple Primary / Q000150:complications / Q000473:pathology / Q000662:veterinary*; D017253:Neurofibromatoses / Q000150:complications / Q000662:veterinary*; D010673:Pheochromocytoma / Q000473:pathology / Q000662:veterinary; D012005:Rectal Prolapse / Q000150:complications / Q000662:veterinary*; D046070:Sea Lions