title: Simple localization of nanofiber scaffolds via SU-8 photoresist and their use for parallel 3D cellular assays.
abstract: A simple, new approach to localizing electrospun nanofiber scaffolds simply by direct writing of SU-8 photoresist followed by UV polymerization is presented. This method allows 3D cell culture arrays to be produced and it can be integrated with microfluidic devices easily to enable low-cost high-throughput cellular assays within an addressable 3D environment, which is attractive for use in drug screening, stem cell research, tissue engineering, and regenerative medicine.
authors.affiliation: Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, PR of China.
authors.forename: Lei
authors.initials: L
authors.lastname: Jiang
authors.forename: Min
authors.initials: M
authors.lastname: Zhang
authors.forename: Jiaxing
authors.initials: J
authors.lastname: Li
authors.forename: Weijia
authors.initials: W
authors.lastname: Wen
authors.forename: Jianhua
authors.initials: J
authors.lastname: Qin
mesh_terms: D001672:Biocompatible Materials / Q000737:chemistry*; D004852:Epoxy Compounds / Q000737:chemistry*; D019344:Lactic Acid / Q000737:chemistry*; D057139:Nanofibers / Q000737:chemistry*; D011100:Polyglycolic Acid / Q000737:chemistry*; D000077182:Polylactic Acid-Polyglycolic Acid Copolymer; D011108:Polymers / Q000737:chemistry*; D016062:Porosity; D046888:Tissue Array Analysis / Q000295:instrumentation / Q000379:methods*
chemical_list: D001672:Biocompatible Materials; D004852:Epoxy Compounds; D011108:Polymers; C520895:SU-8 compound; D000077182:Polylactic Acid-Polyglycolic Acid Copolymer; D011100:Polyglycolic Acid; D019344:Lactic Acid