title: Addition of indoles to oxyallyl cations for facile access to α-indole carbonyl compounds.
abstract: A direct coupling of unprotected indoles and α-halo ketones via in situ generated oxyallyl cation intermediates is described. The reactions efficiently afford α-indole carbonyl compounds with good to quantitative yields.
authors.affiliation: Division of Chemistry & Biological Chemistry, School of Physical & Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore.
authors.forename: Qiang
authors.initials: Q
authors.lastname: Tang
authors.forename: Xingkuan
authors.initials: X
authors.lastname: Chen
authors.forename: Bhoopendra
authors.initials: B
authors.lastname: Tiwari
authors.forename: Yonggui Robin
authors.initials: YR
authors.lastname: Chi
mesh_terms: D003500:Cyclization; D007211:Indoles / Q000138:chemical synthesis / Q000737:chemistry; D007659:Ketones / Q000138:chemical synthesis / Q000737:chemistry; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D007211:Indoles; D007659:Ketones