title: [Rational (injection) of calcitonin for stimulation of the mandibular reparative regeneration].
abstract: This investigation permit to detect, that first resorption stage of the mandible reparative regeneration terminats after fracture 5 days later. Calcitonine injection during 5 days after fracture i.e. in paratiroid hormone dependent stage distorts normal reparative process. Rats with traumatic osteomielitis become 1.5 times more and rats with normal regeneration become 3 times less. Injection calcitonine in KT-dependent stage, i.e. in 6-11 days after fracture increases quantity of rats with normal regeneration in 7 times and decreases quantity animals with traumatic osteomielitis on 50%. There's recommendation to inject KT from 6 days after trauma.
authors.forename: M B
authors.initials: MB
authors.lastname: Shvyrkov
mesh_terms: D000818:Animals; D001861:Bone Regeneration / Q000187:drug effects*; D002116:Calcitonin / Q000008:administration & dosage* / Q000097:blood; D008297:Male; D008334:Mandible / Q000502:physiology*; D008337:Mandibular Fractures / Q000097:blood / Q000188:drug therapy*; D051381:Rats
chemical_list: D002116:Calcitonin