title: Application of mixture analysis to crude materials from natural resources (III): NMR spectral studies to analyze chalcones from Angelica keiskei.
abstract: This study presents the application of the NMR-based analyses, DOSY and ROSY, to the chalcones, xanthoangelol (1) and 4-hydroxyderricin (2) from Angelica keiskei. We investigated whether virtual separation and structural information from each compound can be obtained. DOSY displays spectra of (1) and (2) in one dimension and diffusion spectra in the other. And the 1H slice spectra were analyzed in detail by comparison with authentic samples previously isolated from the same material. The resulting ROSY spectrum clearly showed two distinct peaks in the 1H T1 dimension. Each slice of the ROSY spectrum along the 13C dimension contains over-lapped signals, which are difficult to assign at this time.
authors.affiliation: Department of Natural Medicine and Phytochemistry, Meiji Pharmaceutical University, 2-522-1 Noshio, Kiyose, Tokyo 204-8588, Japan.
authors.forename: Eriko
authors.initials: E
authors.lastname: Fukuda
authors.forename: Masaki
authors.initials: M
authors.lastname: Baba
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Uesawa
authors.forename: Osamu
authors.initials: O
authors.lastname: Kamo
authors.forename: Kazunori
authors.initials: K
authors.lastname: Arifuku
authors.forename: Koji
authors.initials: K
authors.lastname: Tsubono
authors.forename: Yoshihito
authors.initials: Y
authors.lastname: Okada
mesh_terms: D029969:Angelica / Q000737:chemistry*; D047188:Chalcones / Q000032:analysis*; D045424:Complex Mixtures / Q000032:analysis; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*
chemical_list: D047188:Chalcones; D045424:Complex Mixtures