title: Acute malignant intestinal obstruction accompanied by synchronous multifocal intestinal cancer in Peutz-Jeghers syndrome: report of a case.
abstract: Acute mechanical intestinal obstruction is one of the most common modes of presentation in patients with Peutz-Jeghers syndrome (PJS). This report presents a case of PJS with malignant acute jejunal obstruction accompanied by synchronous foci of duodenal, jejunal, and ileal cancer originated from hamartomatous polyps. The follow-up endoscopic findings of the patient also revealed severe polyposis of the entire gastrointestinal tract, including the stomach and colon, in addition to the small intestine. Very few cases of multifocal synchronous small intestinal cancer in PJS patients have been reported in the previous literature.
authors.affiliation: Department of General Surgery, Istanbul Medeniyet University Goztepe Education and Research Hospital, Dr. Erkin Street, Kadikoy, Istanbul, Turkey. drtunceren@yahoo.com
authors.forename: Tunc
authors.initials: T
authors.lastname: Eren
authors.forename: Baris
authors.initials: B
authors.lastname: Bayraktar
authors.forename: Yahya
authors.initials: Y
authors.lastname: Celik
authors.forename: Salih
authors.initials: S
authors.lastname: Boluk
authors.forename: Gupse
authors.initials: G
authors.lastname: Adali
mesh_terms: D000006:Abdomen, Acute / Q000175:diagnosis / Q000209:etiology; D003110:Colonic Neoplasms / Q000473:pathology* / Q000601:surgery; D003113:Colonoscopy / Q000379:methods; D004379:Duodenal Neoplasms / Q000473:pathology* / Q000601:surgery; D004384:Duodenoscopy / Q000379:methods; D004636:Emergency Service, Hospital; D005500:Follow-Up Studies; D006801:Humans; D007415:Intestinal Obstruction / Q000209:etiology / Q000473:pathology* / Q000601:surgery; D044483:Intestinal Polyposis / Q000473:pathology / Q000601:surgery; D007580:Jejunal Neoplasms / Q000150:complications / Q000473:pathology* / Q000601:surgery; D007813:Laparotomy / Q000379:methods; D008297:Male; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000473:pathology* / Q000601:surgery; D010580:Peutz-Jeghers Syndrome / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D049268:Positron-Emission Tomography / Q000379:methods; D018570:Risk Assessment; D014057:Tomography, X-Ray Computed / Q000379:methods; D016896:Treatment Outcome