title: Five to ten years follow-up after coiling of 241 patients with acutely ruptured aneurysms. A single centre experience.
abstract: Endovascular treatment has assumed a role of first choice in the management of ruptured intracranial aneurysms. We describe the clinical and morphological data after the treatment of 258 ruptured intracranial aneurysms in 241 patients, in order to evaluate the safety and the efficacy of the endovascular treatment.     Two hundred and forty-one patients with saccular ruptured aneurysms were treated at our institution between 2000 and 2005. After the endovascular treatment a clinical and angiographic follow-up was conducted. The clinical follow-up was carried out with a medical examination and telephonic interviews and mRS was used for evaluation.     Two hundred and forty-nine acutely ruptured aneurysms were successfully treated and immediately after the endovascular procedure 81.9% of the aneurysms resulted completely occluded, 12.1% had a residual neck and 6% revealed a residual sac. The evolution of each grade was evaluated at six months and two years. During the follow-up we observed five early and one late re-bleedings. Twenty-four patients underwent a second procedure. After the discharge and up to ten years 73.1% of patients had a good clinical outcome (mRS0-1), 8.9% died and the remainder showed moderate-severe disability (mRS2-3).     The long-term stability of the anatomical result is a critic-al issue of this approach because eventual re-bleedings may occur even after several months or years. A careful clinical and radiological follow-up for up to two years after the embolization may prevent recurrences but may not be sufficient.
authors.affiliation: Interventional Neuroradiology Unit, Careggi University Hospital, Florence, Italy. onemed21@gmail.com
authors.forename: A
authors.initials: A
authors.lastname: Consoli
authors.forename: L
authors.initials: L
authors.lastname: Renieri
authors.forename: R
authors.initials: R
authors.lastname: Mura
authors.forename: S
authors.initials: S
authors.lastname: Nappini
authors.forename: F
authors.initials: F
authors.lastname: Ricciardi
authors.forename: G
authors.initials: G
authors.lastname: Pecchioli
authors.forename: F
authors.initials: F
authors.lastname: Ammannati
authors.forename: S
authors.initials: S
authors.lastname: Mangiafico
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D017542:Aneurysm, Ruptured / Q000000981:diagnostic imaging* / Q000628:therapy*; D002543:Cerebral Hemorrhage / Q000000981:diagnostic imaging; D004621:Embolization, Therapeutic / Q000009:adverse effects; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D002532:Intracranial Aneurysm / Q000000981:diagnostic imaging* / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D011859:Radiography; D012008:Recurrence; D019233:Retreatment; D013997:Time Factors; D016896:Treatment Outcome; D055815:Young Adult