title: Malaria vaccine development using synthetic peptides as a technical platform.
abstract: The review covers the development of synthetic peptides as vaccine candidates for Plasmodium falciparum- and Plasmodium vivax-induced malaria from its beginning up to date and the concomitant progress of solid phase peptide synthesis (SPPS) that enables the production of long peptides in a routine fashion. The review also stresses the development of other complementary tools and actions in order to achieve the long sought goal of an efficacious malaria vaccine.
authors.affiliation: Biochemstry Department, University of Lausanne, Epalinges, Switzerland.
authors.forename: Giampietro
authors.initials: G
authors.lastname: Corradin
authors.forename: Nora
authors.initials: N
authors.lastname: Céspedes
authors.forename: Antonio
authors.initials: A
authors.lastname: Verdini
authors.forename: Andrey V
authors.initials: AV
authors.lastname: Kajava
authors.forename: Myriam
authors.initials: M
authors.lastname: Arévalo-Herrera
authors.forename: Sócrates
authors.initials: S
authors.lastname: Herrera
mesh_terms: D000953:Antigens, Protozoan / Q000276:immunology*; D006801:Humans; D008288:Malaria / Q000276:immunology / Q000517:prevention & control; D017780:Malaria Vaccines / Q000276:immunology*; D010963:Plasmodium falciparum / Q000276:immunology; D010966:Plasmodium vivax / Q000276:immunology; D015800:Protozoan Proteins / Q000276:immunology*; D022223:Vaccines, Subunit / Q000276:immunology*; D014614:Vaccines, Synthetic / Q000276:immunology*
chemical_list: D000953:Antigens, Protozoan; D017780:Malaria Vaccines; D015800:Protozoan Proteins; D022223:Vaccines, Subunit; D014614:Vaccines, Synthetic; C089133:merozoite surface protein 3, Plasmodium