title: Comparative characteristics of the morphology of rabbit lymph nodes after implantation of porous titanium with composite nanocoating and hydroxyapatite particles embedded into pores.
abstract: We studied changes of microarchitectonics of lymph nodes in mature rabbits in response to introduction of bioimplants based on porous titanium with carbon-containing nanocoating or nanocoating with hydroxyapatite embedded into pores. Moderate local reactivity of the lymphoid system was observed in animals with implants coated with carbon-containing films within 30 days after surgery. In animals with nanocoated implants containing hydroxyapatite, the immune response was more pronounced. Introduction of implants led to activation of cellular and humoral mechanisms of immunity in animals of both groups.
authors.affiliation: Biochemical and immunological laboratory, FSI V. D Chaklin Ural Research Institute of Traumatology and Orthopedics, Ministry of Health and Social Development of Russian Federation, Ekaterinburg, Russia. emilia1907@yandex.ru
authors.forename: E B
authors.initials: EB
authors.lastname: Makarova
authors.forename: N S
authors.initials: NS
authors.lastname: Kiselyova
authors.forename: M A
authors.initials: MA
authors.lastname: Smetankina
authors.forename: D G
authors.initials: DG
authors.lastname: Bliznets
authors.forename: A P
authors.initials: AP
authors.lastname: Rubstein
authors.forename: N B
authors.initials: NB
authors.lastname: Krokhina
mesh_terms: D000818:Animals; D000917:Antibody Formation; D001672:Biocompatible Materials; D017886:Durapatite; D007111:Immunity, Cellular; D008198:Lymph Nodes / Q000033:anatomy & histology* / Q000276:immunology; D049329:Nanostructures; D019736:Prostheses and Implants; D011817:Rabbits; D014025:Titanium
chemical_list: D001672:Biocompatible Materials; D017886:Durapatite; D014025:Titanium