title: Concise approach to benzisothiazol-3(2H)-one via copper-catalyzed tandem reaction of o-bromobenzamide and potassium thiocyanate in water.
abstract: A concise approach to various benzisothiazol-3(2H)-one derivatives has been developed by copper-catalyzed the reaction of o-bromobenzamide derivatives with potassium thiocyanate (KSCN) in water. The reaction proceeds via a tandem reaction with S-C bond and S-N bond formation.
authors.affiliation: Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University, Beijing 100084, China.
authors.forename: Fei
authors.initials: F
authors.lastname: Wang
authors.forename: Chao
authors.initials: C
authors.lastname: Chen
authors.forename: Geng
authors.initials: G
authors.lastname: Deng
authors.forename: Chanjuan
authors.initials: C
authors.lastname: Xi
mesh_terms: D001549:Benzamides / Q000138:chemical synthesis* / Q000737:chemistry*; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D015394:Molecular Structure; D013861:Thiocyanates / Q000138:chemical synthesis* / Q000737:chemistry*; D014230:Triazoles / Q000138:chemical synthesis* / Q000737:chemistry*; D014867:Water
chemical_list: D001549:Benzamides; D013861:Thiocyanates; D014230:Triazoles; C573968:benzisothiazol-3(2H)-one; C573969:o-bromobenzamide; D014867:Water; D003300:Copper; C009941:potassium thiocyanate