title: Myoclonus precipitated by oral suspension of oxcarbazepine in idiopathic generalized epilepsy.
abstract: Oxcarbazepine (OXC) is widely registered for the treatment of partial seizures and generalized tonic-clonic seizures (GTCS). Myoclonic seizures induced by OXC are uncommon. We report a child with idiopathic generalized epilepsy who developed myoclonic seizures and had an abnormal electroencephalogram (EEG) when oral suspension of OXC was introduced. This study suggests that oral suspension of OXC can precipitate myoclonus.
authors.affiliation: Department of Neuropediatrics, Key Laboratory of Obstetric and Gynecologic and Pediatric Diseases and Birth Defects of Ministry of Education, Sichuan University, Chengdu, China.
authors.forename: Songqing
authors.initials: S
authors.lastname: Deng
authors.forename: Rong
authors.initials: R
authors.lastname: Luo
authors.forename: Meng
authors.initials: M
authors.lastname: Mao
authors.forename: Liang
authors.initials: L
authors.lastname: Huang
mesh_terms: D000284:Administration, Oral; D000927:Anticonvulsants / Q000008:administration & dosage / Q000009:adverse effects*; D002220:Carbamazepine / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives*; D057915:Drug Substitution; D004569:Electroencephalography; D004831:Epilepsies, Myoclonic / Q000139:chemically induced* / Q000175:diagnosis / Q000503:physiopathology; D004829:Epilepsy, Generalized / Q000175:diagnosis / Q000188:drug therapy* / Q000503:physiopathology; D005260:Female; D006801:Humans; D007223:Infant; D000078330:Oxcarbazepine; D016896:Treatment Outcome; D014635:Valproic Acid / Q000008:administration & dosage
chemical_list: D000927:Anticonvulsants; D002220:Carbamazepine; D014635:Valproic Acid; D000078330:Oxcarbazepine