title: Environmental conditions that influence toxin biosynthesis in cyanobacteria.
abstract: Over the past 15 years, the genetic basis for production of many cyanobacterial bioactive compounds has been described. This knowledge has enabled investigations into the environmental factors that regulate the production of these toxins at the molecular level. Such molecular or systems level studies are also likely to reveal the physiological role of the toxin and contribute to effective water resource management. This review focuses on the environmental regulation of some of the most relevant cyanotoxins, namely the microcystins, nodularin, cylindrospermopsin, saxitoxins, anatoxins and jamaicamides.
authors.affiliation: School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, New South Wales, Australia. b.neilan@unsw.edu.au
authors.forename: Brett A
authors.initials: BA
authors.lastname: Neilan
authors.forename: Leanne A
authors.initials: LA
authors.lastname: Pearson
authors.forename: Julia
authors.initials: J
authors.lastname: Muenchhoff
authors.forename: Michelle C
authors.initials: MC
authors.lastname: Moffitt
authors.forename: Elke
authors.initials: E
authors.lastname: Dittmann
mesh_terms: D000458:Cyanobacteria / Q000235:genetics* / Q000378:metabolism*; D004777:Environment; D015964:Gene Expression Regulation, Bacterial; D008387:Marine Toxins / Q000096:biosynthesis / Q000235:genetics; D052998:Microcystins / Q000096:biosynthesis* / Q000737:chemistry / Q000235:genetics; D010453:Peptide Synthases / Q000235:genetics
chemical_list: D008387:Marine Toxins; D052998:Microcystins; D010453:Peptide Synthases