title: Pharmacodynamic considerations for moderate and deep sedation.
abstract: Moderate and deep sedation can be provided using various classes of drugs, each having unique mechanisms of action. While drugs within a given classification share similar mechanisms and effects, certain classes demonstrate superior efficacy but added concern regarding safety. This continuing education article will highlight essential principles of pharmacodynamics and apply these to drugs commonly used to produce moderate and deep sedation.
authors.affiliation: Miami Valley Hospital, Dayton, OH, USA. debecker@mvh.org
authors.forename: Daniel E
authors.initials: DE
authors.lastname: Becker
mesh_terms: D000701:Analgesics, Opioid / Q000494:pharmacology; D000768:Anesthesia, General / Q000145:classification; D001569:Benzodiazepines / Q000494:pharmacology; D016292:Procedural Sedation / Q000145:classification / Q000379:methods*; D054810:Deep Sedation / Q000145:classification / Q000379:methods*; D006801:Humans; D006993:Hypnotics and Sedatives / Q000145:classification / Q000494:pharmacology*; D009609:Nitrous Oxide / Q000494:pharmacology
chemical_list: D000701:Analgesics, Opioid; D006993:Hypnotics and Sedatives; D001569:Benzodiazepines; D009609:Nitrous Oxide