title: The primary Maxillary Central Incisor in the Solitary Median Maxillary Central Incisor syndrome.
abstract: OBJECTIVE
  Solitary Median Maxillary Central Incisor (SMMCI) is a developmental anomaly in the permanent dentition  with one single central incisor in the maxilla, positioned exactly in the midline. This condition has been associated with  extra- and intraoral malformations in the frontonasal segment of the cranium and face. It is not known whether the centrally  located permanent incisor is always preceded by a centrally located primary incisor. The aim was to analyse whether a  permanent single central incisor in SMMCI is always preceded by a primary single central incisor and to study extra- and  intraoral phenotypic traits of the condition.
  
  
  METHODS
  
  
  
  METHODS
  cross-sectional radiographic study  of 11 children, visual analysis of photos and dental and panoramic radiographs.
  
  
  RESULTS
  Nine of the 11 cases exhibited a  primary SMMCI with one symmetrical crown and root. Two cases exhibited two separate primary central incisor crowns with  fused roots. The phenotypical traits (indistinct philtrum, lack of normal upper lip contour, missing superior labial frenulum  and distinct mid-palatal ridge) were findings observed in young children with a primary SMMCI.
  
  
  CONCLUSIONS
  The present  study concludes and stresses the necessity of diagnosing of the SMMCI condition early in life. Furthermore, paediatric  dentists are recommended to be aware of the condition and to refer these patients to interdisciplinary diagnostics and  treatment.
authors.affiliation: Department of Orthodontics, Institute of Odontology, Faculty of Health Sciences, University of Copenhagen, Denmark.
authors.forename: I
authors.initials: I
authors.lastname: Kjaer
authors.forename: M
authors.initials: M
authors.lastname: Balslev-Olesen
mesh_terms: D000015:Abnormalities, Multiple; D000848:Anodontia / Q000000981:diagnostic imaging / Q000473:pathology*; D002648:Child; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D005260:Female; D005671:Fused Teeth / Q000000981:diagnostic imaging; D006801:Humans; D007180:Incisor / Q000002:abnormalities* / Q000000981:diagnostic imaging; D007742:Labial Frenum / Q000002:abnormalities; D008046:Lip / Q000002:abnormalities; D008297:Male; D008437:Maxilla / Q000000981:diagnostic imaging / Q000473:pathology*; D021362:Palate, Hard / Q000002:abnormalities; D010641:Phenotype; D011859:Radiography; D013577:Syndrome; D019228:Tooth Crown / Q000002:abnormalities / Q000000981:diagnostic imaging; D014092:Tooth Root / Q000002:abnormalities / Q000000981:diagnostic imaging; D014094:Tooth, Deciduous / Q000002:abnormalities / Q000000981:diagnostic imaging