title: [ARCHITECT Chagas(®): a new diagnostic tool in Chagas disease].
abstract: OBJECTIVE
  To evaluate a new chemiluminescent microparticle immunoassay (ARCHITECT Chagas(®), Abbott).
  
  
  METHODS
  In this study, 165 samples were tested by two different serological tests. The ARCHITECT Chagas(®) assay was performed using ARCHITECT i2000(SR) system (Abbott).
  
  
  RESULTS
  The sensitivity and specificity of ARCHITECT assay was 100% and 96.6%, respectively. The concordance rate was 0.96 (95%CI: 0.92-1) for ELISA and 0.91 (95%CI: 0.85-0.97) for immunofluorescence assay (IFA).
  
  
  CONCLUSIONS
  The ARCHITECT Chagas(®) assay demonstrates a sensitivity and specificity similar to ELISA and IFA assays; it allows a large volume of samples to be processed with a good standardization and reproducibility, as well as an objective interpretation.
authors.affiliation: Servicio de Microbiología y Parasitología, Hospital Universitario Virgen de la Arrixaca, El Palmar, Murcia, España. asunib@yahoo.com
authors.forename: M Asunción
authors.initials: MA
authors.lastname: Iborra-Bendicho
authors.forename: Miriam
authors.initials: M
authors.lastname: Albert-Hernández
authors.forename: Carmen
authors.initials: C
authors.lastname: Márquez-Contreras
authors.forename: Manuel
authors.initials: M
authors.lastname: Segovia-Hernández
mesh_terms: D000913:Antibodies, Protozoan / Q000097:blood*; D000953:Antigens, Protozoan / Q000276:immunology; D014355:Chagas Disease / Q000097:blood / Q000175:diagnosis*; D004797:Enzyme-Linked Immunosorbent Assay; D019084:Fluorescent Antibody Technique, Indirect; D006801:Humans; D007118:Immunoassay / Q000379:methods*; D008163:Luminescent Measurements; D011933:Reagent Kits, Diagnostic; D015203:Reproducibility of Results; D012494:Sampling Studies; D012680:Sensitivity and Specificity; D014349:Trypanosoma cruzi / Q000276:immunology
chemical_list: D000913:Antibodies, Protozoan; D000953:Antigens, Protozoan; D011933:Reagent Kits, Diagnostic