title: Management of multifocal and multicentric gliomas.
abstract: The diffuse nature of gliomas has long confounded attempts at achieving a definitive cure. The advent of computed tomography and magnetic resonance imaging made it increasingly apparent that gliomas could have a multifocal or multicentric appearance. Treating these tumors is the summit of an already daunting challenge, because the obstacles that must be surmounted to treat gliomas in general, namely, their heterogeneity, diffuse nature, and ability to insidiously invade normal brain, are more conspicuous in this subset of tumors.
authors.affiliation: Department of Neurological Surgery, Cedars-Sinai Medical Center, Los Angeles, CA, USA. chiragpatil@gmail.com
authors.forename: Chirag G
authors.initials: CG
authors.lastname: Patil
authors.forename: Paula
authors.initials: P
authors.lastname: Eboli
authors.forename: Jethro
authors.initials: J
authors.lastname: Hu
mesh_terms: D001932:Brain Neoplasms / Q000473:pathology / Q000628:therapy*; D005910:Glioma / Q000473:pathology / Q000628:therapy*; D006801:Humans; D009378:Neoplasms, Multiple Primary / Q000473:pathology*