title: A novel pathway of photoinduced decomposition of sphingolipids.
abstract: A possibility of a novel photodestruction process has been shown for sphingolipids and their low-molecular analogues, including the stage of Norrish Type-I decomposition of excited molecules of the starting compounds followed by fragmentation of nitrogen-centered radicals via rupture of the C-C and O-H bonds. Realization of such transformation during photolysis of ceramide, sphingomyelin and galactocerebroside results in formation of 2-hexadecenal, which possess a wide spectrum of biological activity.
authors.affiliation: Department of Chemistry, Belarusian State University, Minsk, Belarus.
authors.forename: Alexandra G
authors.initials: AG
authors.lastname: Lisovskaya
authors.forename: Irina P
authors.initials: IP
authors.lastname: Edimecheva
authors.forename: Oleg I
authors.initials: OI
authors.lastname: Shadyro
mesh_terms: D000447:Aldehydes / Q000737:chemistry*; D002518:Ceramides / Q000737:chemistry*; D002851:Chromatography, High Pressure Liquid; D005609:Free Radicals; D005699:Galactosylceramides / Q000737:chemistry*; D008401:Gas Chromatography-Mass Spectrometry; D008081:Liposomes / Q000737:chemistry; D015394:Molecular Structure; D009584:Nitrogen / Q000737:chemistry; D010782:Photolysis; D013109:Sphingomyelins / Q000737:chemistry*; D014466:Ultraviolet Rays
chemical_list: D000447:Aldehydes; D002518:Ceramides; D005609:Free Radicals; D005699:Galactosylceramides; D008081:Liposomes; D013109:Sphingomyelins; C002454:galactocerebroside; D009584:Nitrogen; C519712:2-hexadecenal