title: Mueller matrix polarimetry for improved liver fibrosis diagnosis.
abstract: An experimental Mueller matrix polarimeter is used to quantify human liver fibrosis by measuring retardance and depolarization of thin biopsies. The former parameter is sensitive to fibrillar collagen, the latter is specifically sensitive to fibrillar collagen around blood vessels, which is not significant for liver fibrosis diagnosis. By using depolarization like a filter, retardance distribution enables distinguishing between disease stages and limits the high degree of observer discrepancy.
authors.affiliation: Université de Brest, UEB, EA 938 Laboratoire de Spectrométrie et Optique Laser, Brest, France. matthieu.dubreuil@univ‑brest.fr
authors.forename: Matthieu
authors.initials: M
authors.lastname: Dubreuil
authors.forename: Philippe
authors.initials: P
authors.lastname: Babilotte
authors.forename: Loïc
authors.initials: L
authors.lastname: Martin
authors.forename: David
authors.initials: D
authors.lastname: Sevrain
authors.forename: Sylvain
authors.initials: S
authors.lastname: Rivet
authors.forename: Yann
authors.initials: Y
authors.lastname: Le Grand
authors.forename: Guy
authors.initials: G
authors.lastname: Le Brun
authors.forename: Bruno
authors.initials: B
authors.lastname: Turlin
authors.forename: Bernard
authors.initials: B
authors.lastname: Le Jeune
mesh_terms: D006801:Humans; D008099:Liver / Q000473:pathology; D008103:Liver Cirrhosis / Q000175:diagnosis* / Q000473:pathology; D055620:Optical Phenomena