title: Metformin, metabolic stress, and mitochondria. Focus on "A novel inverse relationship between metformin-triggered AMPK-SIRT1 signaling and p53 protein abundance in high glucose-exposed HepG2 cells".
authors.forename: Mary C
authors.initials: MC
authors.lastname: Sugden
authors.forename: Mark J
authors.initials: MJ
authors.lastname: Holness
mesh_terms: D055372:AMP-Activated Protein Kinases / Q000378:metabolism*; D005947:Glucose / Q000494:pharmacology*; D006801:Humans; D008687:Metformin / Q000494:pharmacology*; D056564:Sirtuin 1 / Q000378:metabolism*; D016159:Tumor Suppressor Protein p53 / Q000378:metabolism*
chemical_list: C495901:TP53 protein, human; D016159:Tumor Suppressor Protein p53; D008687:Metformin; D055372:AMP-Activated Protein Kinases; C447939:SIRT1 protein, human; D056564:Sirtuin 1; D005947:Glucose