title: Papillary thyroid carcinoma: differential diagnosis and prognostic values of its different variants: review of the literature.
abstract: Papillary thyroid carcinoma is the most common thyroid malignancy, and has an excellent prognosis, even with cervical lymph node metastasis; however, histological variants are considered relevant, which may be associated with familial adenomatous polyposis and tumor aggressiveness. Histological features, such as vascular and/or lymphatic invasion, angiogenesis, multifocality, high cellular proliferation rate, neoplastic cell dissemination, and the histological varieties, are indicative of poor prognosis, together with associated clinical factors: age, sex, and tumor size.
authors.affiliation: Universidad Autónoma Metropolitana, México City, Mexico.
authors.forename: Rogelio
authors.initials: R
authors.lastname: Gonzalez-Gonzalez
authors.forename: Ronell
authors.initials: R
authors.lastname: Bologna-Molina
authors.forename: Ramón Gil
authors.initials: RG
authors.lastname: Carreon-Burciaga
authors.forename: Marcelo
authors.initials: M
authors.lastname: Gómezpalacio-Gastelum
authors.forename: Nelly
authors.initials: N
authors.lastname: Molina-Frechero
authors.forename: Sirced
authors.initials: S
authors.lastname: Salazar-Rodríguez