title: Polypropylene mesh and the host response.
abstract: The use of polypropylene (PP) mesh for pelvic floor repair has been increasing dramatically over the past decade; however, tissue response in humans has not been extensively studied. This review discusses PP mesh and postimplantation host tissue response. Emphasis is placed on studies investigating the relationship between individual mesh properties and specific responses. There is an immediate inflammatory response after PP mesh implantation that lays the framework for tissue ingrowth and subsequent mesh integration. This response varies based on physical properties of individual mesh, such as pore size, weight, coatings, bacterial colonization, and biofilm production.
authors.affiliation: Long Beach Memorial Medical Center, Women's Hospital, Long Beach, CA 90806, USA. Hiren.Patel.DO@gmail.com
authors.forename: Hiren
authors.initials: H
authors.lastname: Patel
authors.forename: Donald R
authors.initials: DR
authors.lastname: Ostergard
authors.forename: Gina
authors.initials: G
authors.lastname: Sternschuss
mesh_terms: D000818:Animals; D001672:Biocompatible Materials; D005260:Female; D046449:Hernia, Abdominal / Q000601:surgery*; D059685:Herniorrhaphy / Q000379:methods*; D006801:Humans; D008422:Materials Testing / Q000379:methods*; D056887:Pelvic Organ Prolapse / Q000601:surgery*; D011126:Polypropylenes; D013526:Surgical Mesh; D013520:Urologic Surgical Procedures / Q000379:methods*
chemical_list: D001672:Biocompatible Materials; D011126:Polypropylenes