title: Concurrent metastatic thymic carcinoma and postirradiation sarcoma.
abstract: We present a case of concurrent metastatic thymic carcinoma and postirradiation sarcoma in the same lobe of the lung in a woman who had received partial resection of thymic carcinoma with chemoradiotherapy 11 years ago. One tumor showed similar histology to the previous carcinoma. The other tumor was a pleomorphic sarcoma, suggestive of a postirradiation sarcoma. Irradiation-induced sarcomas are rare and have not been reported in patients with thymic carcinoma. This case may serve as a model in considering the possibility of postirradiation sarcoma for patients encountering recurrent masses with the history of radiotherapy for thymic carcinoma several years ago.
authors.affiliation: Department of Pathology, Kaohsiung Medical University Hospital and Kaohsiung Medical University, Kaohsiung, Taiwan.
authors.forename: Tzu-Ju
authors.initials: TJ
authors.lastname: Chen
authors.forename: Hung-I
authors.initials: HI
authors.lastname: Lu
authors.forename: Cheng-Hua
authors.initials: CH
authors.lastname: Huang
authors.forename: Hsuan-Chih
authors.initials: HC
authors.lastname: Hsu
authors.forename: Sung-Ting
authors.initials: ST
authors.lastname: Chen
authors.forename: Wei-jen
authors.initials: WJ
authors.lastname: Chen
authors.forename: Chao-Cheng
authors.initials: CC
authors.lastname: Huang
mesh_terms: D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000556:secondary / Q000601:surgery*; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis / Q000601:surgery*; D009381:Neoplasms, Radiation-Induced / Q000473:pathology / Q000601:surgery*; D012509:Sarcoma / Q000209:etiology / Q000473:pathology / Q000601:surgery*; D013953:Thymus Neoplasms / Q000473:pathology / Q000628:therapy*