title: Sonic hedgehog, BOC, and synaptic development: new players for an old game.
abstract: In this issue of Neuron, Harwell et al. (2012) identify a new role for the secreted molecule Shh and its receptor Boc in synapse formation. These results add an unexpected new player to the expanding list of extracellular cues regulating the spatial specificity of synapse formation.
authors.affiliation: Department of Cell Biology, Dorris Neuroscience Center, The Scripps Research Institute, La Jolla, CA 92037, USA.
authors.forename: Julien
authors.initials: J
authors.lastname: Courchet
authors.forename: Franck
authors.initials: F
authors.lastname: Polleux
mesh_terms: D000818:Animals; D002540:Cerebral Cortex / Q000166:cytology*; D018507:Gene Expression Regulation, Developmental / Q000502:physiology*; D053823:Hedgehog Proteins / Q000378:metabolism*; D009415:Nerve Net / Q000378:metabolism*; D009474:Neurons / Q000378:metabolism*; D011712:Pyramidal Tracts / Q000502:physiology*
chemical_list: D053823:Hedgehog Proteins; C465570:Shh protein, mouse