title: Biochemical changes in rat brain exposed to low intensity 9.9 GHz microwave radiation.
abstract: Present study concerns with various biochemical changes in the developing rat brain exposed to 9.9 GHz (square wave modulated, 1 kHz) at power density 0.125 mW/cm(2) (specific absorption rate 1.0 W/kg) for 2 h/day for 35 days. Thirty days old male wistar rats were used for this present study. Each group consists of eight animals. After the exposure, biochemical assays such as calcium ion efflux, calcium-dependent protein kinase (PKC), and ornithine decarboxylase (ODC) were performed on the brain tissue. Results of this study reveal that chronic exposure of rat to microwave radiation alter the activity of certain enzymes. There was a significant increase in calcium ion efflux and the activity of ODC. On the other hand, there is a significant decrease in PKC activity. Since these enzymes are related to growth, any alteration may lead to affect functioning of the brain and its development.
authors.affiliation: School of Environmental Sciences, Jawaharlal Nehru University, New Delhi, India.
authors.forename: R
authors.initials: R
authors.lastname: Paulraj
authors.forename: J
authors.initials: J
authors.lastname: Behari
mesh_terms: D000818:Animals; D001921:Brain / Q000201:enzymology / Q000378:metabolism* / Q000528:radiation effects*; D002118:Calcium / Q000378:metabolism; D008297:Male; D008872:Microwaves; D009955:Ornithine Decarboxylase / Q000378:metabolism; D011494:Protein Kinases / Q000378:metabolism; D051381:Rats; D017208:Rats, Wistar; D017871:Calcium-Calmodulin-Dependent Protein Kinases
chemical_list: D002118:Calcium; D009955:Ornithine Decarboxylase; D011494:Protein Kinases; D017871:Calcium-Calmodulin-Dependent Protein Kinases