title: A case of nephrocalcinosis associated with primary aldosteronism.
abstract: Herein, we report a 37-year-old man presenting with nephrocalcinosis associated with primary aldosteronism. Primary hyperaldosteronism is reported to facilitate urinary calcium excretion; however, renal calculi or calcinosis in this disorder has been rarely reported. The patient had renal dysfunction and calcification in the renal medulla on both kidneys. A kidney biopsy was performed. His renal dysfunction seemed to be mainly caused by hypertension and tubulointerstitial damage. Furthermore, von Kossa-positive stones were seen in some tubules. X-ray element analysis revealed that the stones were composed of calcium phosphate.
authors.affiliation: Department of Nephrology, Rinku General Medical Center, Japan. k-yasuda@rgmc.izumisano.osaka.jp
authors.forename: Keiko
authors.initials: K
authors.lastname: Yasuda
authors.forename: Koichi
authors.initials: K
authors.lastname: Sasaki
authors.forename: Masaya
authors.initials: M
authors.lastname: Yamato
authors.forename: Hiromi
authors.initials: H
authors.lastname: Rakugi
authors.forename: Yoshitaka
authors.initials: Y
authors.lastname: Isaka
authors.forename: Terumasa
authors.initials: T
authors.lastname: Hayashi
mesh_terms: D000306:Adrenal Cortex Neoplasms / Q000378:metabolism / Q000601:surgery; D018246:Adrenocortical Adenoma / Q000378:metabolism / Q000601:surgery; D000328:Adult; D002118:Calcium / Q000378:metabolism*; D002130:Calcium Phosphates / Q000032:analysis; D003937:Diagnosis, Differential; D006801:Humans; D006929:Hyperaldosteronism / Q000150:complications* / Q000175:diagnosis; D006973:Hypertension / Q000150:complications; D007669:Kidney Calculi / Q000737:chemistry; D007678:Kidney Glomerulus / Q000473:pathology; D008297:Male; D009397:Nephrocalcinosis / Q000209:etiology* / Q000473:pathology; D053040:Nephrolithiasis / Q000209:etiology*; D014057:Tomography, X-Ray Computed
chemical_list: D002130:Calcium Phosphates; C020243:calcium phosphate; D002118:Calcium