title: Impact of age and body site on adult female skin surface pH.
abstract: BACKGROUND
  pH is known as an important parameter in epidermal barrier function and homeostasis.
  
  
  OBJECTIVE
  The impact of age and body site on skin surface pH (pH(SS)) of women was evaluated in vivo.
  
  
  METHODS
  Time domain dual lifetime referencing with luminescent sensor foils was used for pH(SS) measurements. pH(SS) was measured on the forehead, the temple, and the volar forearm of adult females (n = 97, 52.87 ± 18.58 years, 20-97 years). Every single measurement contained 2,500 pH values due to the luminescence imaging technique used.
  
  
  RESULTS
  pH(SS) slightly increases with age on all three investigated body sites. There are no significant differences in pH(SS) between the three investigated body sites.
  
  
  CONCLUSIONS
  Adult pH(SS) on the forehead, the temple and the volar forearm increases slightly with age. This knowledge is crucial for adapting medical skin care products.
authors.affiliation: Department of Dermatology, University Hospital Regensburg, Regensburg, Germany.
authors.forename: Stephan
authors.initials: S
authors.lastname: Schreml
authors.forename: Veronika
authors.initials: V
authors.lastname: Zeller
authors.forename: Robert Johannes
authors.initials: RJ
authors.lastname: Meier
authors.forename: Hans Christian
authors.initials: HC
authors.lastname: Korting
authors.forename: Barbara
authors.initials: B
authors.lastname: Behm
authors.forename: Michael
authors.initials: M
authors.lastname: Landthaler
authors.forename: Philipp
authors.initials: P
authors.lastname: Babilas
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005542:Forearm; D005546:Forehead; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008875:Middle Aged; D012867:Skin / Q000378:metabolism*; D012879:Skin Physiological Phenomena; D055815:Young Adult