title: Reduced lung diffusion capacity in type 2 diabetes is independent of heart failure.
abstract: In a case-control analysis comparing 303 patients with diabetes and 303 without (matched on age, race, sex and height), diabetics had reduced lung diffusion (DLCO) independent of smoking, obesity, clinical heart failure, asymptomatic left ventricular systolic and diastolic dysfunction: DLCO (mean±SE: 15.5±0.9 vs. 16.4 ±0.9, p=0.01).
authors.affiliation: Department of Medicine, University of California, San Francisco, CA 94143-0131, USA. oklein@medicine.ucsf.edu
authors.forename: Oana L
authors.initials: OL
authors.lastname: Klein
authors.forename: Madeline
authors.initials: M
authors.lastname: Jones
authors.forename: Jungwha
authors.initials: J
authors.lastname: Lee
authors.forename: Harold R
authors.initials: HR
authors.lastname: Collard
authors.forename: Lewis J
authors.initials: LJ
authors.lastname: Smith
mesh_terms: D016022:Case-Control Studies; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000150:complications / Q000503:physiopathology*; D003925:Diabetic Angiopathies / Q000097:blood / Q000503:physiopathology*; D005260:Female; D006333:Heart Failure / Q000097:blood / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000097:blood / Q000503:physiopathology*; D011653:Pulmonary Diffusing Capacity; D012907:Smoking / Q000009:adverse effects; D013147:Spirometry / Q000379:methods; D018487:Ventricular Dysfunction, Left / Q000097:blood / Q000503:physiopathology*; D014797:Vital Capacity