title: New galloyl derivative from winged sumac (Rhus copallinum) fruit.
abstract: Twelve compounds were isolated from Winged Sumac (Rhus copallinum) fruit and their structures were elucidated on the basis of NMR and mass spectral data. The isolates included a new galloyl derivative, (R)-galloyl malic acid dimethyl ester (1), and eleven known compounds, gallic acid (2), methyl gallate (3), glucogallin (4), methyl m-digallate (5), methyl p-digallate (6), quercetin (7), myricetin (8), rhamnazin (9), kaempferol (10), betulinic acid (11), and oleanolic acid (12). All of the compounds were evaluated for antiproliferative effects against human colon tumorigenic (HCT-116, Caco-2) and nontumorigenic (CCD18-Co) cell lines.
authors.affiliation: Bioactive Botanical Research Laboratory, Department of Biomedical and Pharmaceutical Sciences, College of Pharmacy, University of Rhode Island, Kingston, RI 02881, USA.
authors.forename: Hang
authors.initials: H
authors.lastname: Ma
authors.forename: Tao
authors.initials: T
authors.lastname: Yuan
authors.forename: Antonio
authors.initials: A
authors.lastname: González-Sarrías
authors.forename: Liya
authors.initials: L
authors.lastname: Li
authors.forename: Maxwell E
authors.initials: ME
authors.lastname: Edmonds
authors.forename: Navindra P
authors.initials: NP
authors.lastname: Seeram
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000302:isolation & purification* / Q000494:pharmacology; D045744:Cell Line, Tumor; D005638:Fruit / Q000737:chemistry; D005707:Gallic Acid / Q000031:analogs & derivatives / Q000302:isolation & purification / Q000494:pharmacology; D006801:Humans; D011794:Quercetin / Q000302:isolation & purification / Q000494:pharmacology; D029045:Rhus / Q000737:chemistry*
chemical_list: D000972:Antineoplastic Agents, Phytogenic; C052082:methyl gallate; D005707:Gallic Acid; D011794:Quercetin