title: [Childhood cutaneous granular cell tumor: case report].
abstract: Granular cell tumors (GCT) are benign neoplasms of distinctive differentiation when observed by light microscopy, which are characterized by the presence of cells with abundant granular eosinophilic cytoplasm. Reports in children are extremely rare. An 11-year-old male patient presented with a nodule after six months of evolution, which progressively increased in size, asymptomatic, localized on the back. Exploration revealed an oval nodule, 1.5 cm in diameter, movile, nonadherent, and painless. Histological study revealed a non-encapsulated tumorous lesion formed by large cells, organized in clusters, of abundant cytoplasm containing eosinophilic granules and small, centrally located nuclei. Immunohistochemical study demonstrated the presence of S100. Treatment indicated was local conservative surgical excision. We emphasize the need to biopsy persistent ulcerated solitary nodules, for diagnostic accuracy, highlighting the importance of histopathology because clinical diagnosis is difficult and almost never we think about it, unless the tumor arises on the tongue.
authors.affiliation: Cátedra de Dermatología, Hospital de Clínicas, Universidad Nacional de Asunción, Paraguay. beatrizdimartino@gmail.com
authors.forename: Beatriz
authors.initials: B
authors.lastname: Di Martino Ortiz
authors.forename: Romina
authors.initials: R
authors.lastname: Contreras
authors.forename: Lourdes
authors.initials: L
authors.lastname: Rodríguez Oviedo
authors.forename: Gladys
authors.initials: G
authors.lastname: Argüello
authors.forename: Mirtha
authors.initials: M
authors.lastname: Rodríguez
authors.forename: Oilda
authors.initials: O
authors.lastname: Knopfelmacher
authors.forename: Lourdes
authors.initials: L
authors.lastname: Bolla
mesh_terms: D002648:Child; D016586:Granular Cell Tumor / Q000473:pathology; D006801:Humans; D008297:Male; D012878:Skin Neoplasms / Q000473:pathology