title: Construction of multi-component supramolecular architectures of bile acids and cinchona alkaloids through helical-pitch-synchronized crystallization.
abstract: Molecular assemblies based on helical motifs are of substantial interest from the view point of fundamental science as well as application. In this study, we propose a new class of organic crystal, that is, heteroH-MOC (multi-component organic crystal containing different kinds of helical motifs consisted of different components), and describe successful construction of heteroH-MOCs with P2(1) and P2(1)2(1)2(1) space groups by using steroidal bile acids and cinchona alkaloids. In the P2(1) crystals, two kinds of helices composed of the steroid and alkaloid are arranged in a parallel fashion, while, in the P2(1)2(1)2(1) crystals, those are in a perpendicular fashion. It is remarkable that, in such systems, particularly in the latter crystals, components ingeniously achieved highly-ordered synchronization of periodicity (helical pitches r and periodic distances in the array of helices p), which is first demonstrated in this study through hierarchical interpretation of the crystal structures.
authors.affiliation: 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan. hisaki@mls.eng.osaka-u.ac.jp
authors.forename: Toshiyuki
authors.initials: T
authors.lastname: Sasaki
authors.forename: Norie
authors.initials: N
authors.lastname: Shizuki
authors.forename: Eri
authors.initials: E
authors.lastname: Hiraishi
authors.forename: Ichiro
authors.initials: I
authors.lastname: Hisaki
authors.forename: Norimitsu
authors.initials: N
authors.lastname: Tohnai
authors.forename: Mikiji
authors.initials: M
authors.lastname: Miyata
mesh_terms: D001647:Bile Acids and Salts / Q000737:chemistry*; D002930:Cinchona Alkaloids / Q000737:chemistry*; D003460:Crystallization; D008958:Models, Molecular; D008968:Molecular Conformation
chemical_list: D001647:Bile Acids and Salts; D002930:Cinchona Alkaloids