title: Heritability in cognitive performance: evidence using computer-based testing.
abstract: There is overwhelming evidence of genetic influence on cognition. The effect is seen in general cognitive ability, as well as in specific cognitive domains. A conventional assessment approach using face-to-face paper and pencil testing is difficult for large-scale studies. Computerized neurocognitive testing is a suitable alternative. A total of 267 parent-child dyads were selected from a larger database of computerized neurocognitive test results. Correlations were determined between parent-child dyads, as well as matched parent-child dyads. Univariate regression analyses were estimated to determine the extent to which children's performance could be accounted for by that of their parents, compared with matched control parents. Multiple significant positive correlations in neurocognitive test performance were found in parent-child dyads. Parent performance accounted for a greater proportion of variability in every case. These findings indicated that a computerized neurocognitive battery is an effective tool for studying heritability in cognitive performance in a large sample.
authors.affiliation: Duke University and North Carolina Neuropsychiatry, USA. ahervey@ncneuropsych.com
authors.forename: Aaron S
authors.initials: AS
authors.lastname: Hervey
authors.forename: Kathryn
authors.initials: K
authors.lastname: Greenfield
authors.forename: C Thomas
authors.initials: CT
authors.lastname: Gualtieri
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D003071:Cognition; D003936:Diagnosis, Computer-Assisted; D004522:Educational Status; D005260:Female; D006801:Humans; D007360:Intelligence / Q000235:genetics*; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests / Q000706:statistics & numerical data*; D011594:Psychometrics; D015203:Reproducibility of Results; D012984:Software