title: Influence of cross-linked arabinoxylans on the postprandial blood glucose response in rats.
abstract: Viscous dietary fibers are well established to reduce the blood glucose response to a meal. In this study, arabinoxylans, the most abundant dietary fiber in most cereals, were extracted under alkaline conditions and cross-linked by using laccase. Cross-linking of the arabinoxylans led to gel formation and increased in vitro viscosity almost 100-fold after drying and rehydration. To determine the ability of these cross-linked arabinoxylans to blunt the postprandial blood glucose curve of a meal, arabinoxylans, either native or cross-linked, and either prehydrated or not, were fed to rats as part of a meal, and blood glucose was monitored at intervals after the meal. Cellulose, a nonviscous fiber, served as a control. Cross-linked, but not native, arabinoxylans significantly reduced the area under the blood glucose time curve 5-9% relative to cellulose, indicating that they remained viscous within the gastrointestinal tract, and thus likely provide the health benefits found with other viscous fibers.
authors.affiliation: Department of Food Science and Nutrition, University of Minnesota, 1334 Eckles Avenue, St. Paul, MN 55108, United States.
authors.forename: Barbara
authors.initials: B
authors.lastname: Vogel
authors.forename: Daniel D
authors.initials: DD
authors.lastname: Gallaher
authors.forename: Mirko
authors.initials: M
authors.lastname: Bunzel
mesh_terms: D000818:Animals; D001786:Blood Glucose / Q000032:analysis*; D004043:Dietary Fiber / Q000008:administration & dosage / Q000032:analysis; D006801:Humans; D015394:Molecular Structure; D010936:Plant Extracts / Q000008:administration & dosage / Q000737:chemistry*; D019518:Postprandial Period; D051381:Rats; D017208:Rats, Wistar; D014990:Xylans / Q000008:administration & dosage / Q000737:chemistry*; D003313:Zea mays / Q000737:chemistry*
chemical_list: D001786:Blood Glucose; D004043:Dietary Fiber; D010936:Plant Extracts; D014990:Xylans; C085118:arabinoxylan