title: Health informatics design for assisted diagnosis of subclinical atherosclerosis, structural, and functional arterial age calculus and patient-specific cardiovascular risk evaluation.
abstract: Traditional methods used to assess cardiovascular risk (i.e., the Framingham Risk Score) exhibit clear limitations. To aid in patient-specific risk stratification and diagnosis it has been proposed to evaluate noninvasively structural and functional arterial parameters. A National Public University Center (CUiiDARTE) was created in Uruguay with the aim of developing and applying strategies to improve cardiovascular risk stratification and subclinical vascular disease detection. To this end a health informatics approach and tool was designed, developed, and implemented in CUiiDARTE. Its goals were to: 1) promote screening for subclinical atherosclerosis, 2) develop a centralized database to store information obtained noninvasively from anywhere in our country, 3) develop a biomathematical model integrating values for arterial structure and function into traditional cardiovascular risk assessment, 4) generate a detailed and comprehensive report for the specialist comparing patient data with reference data from the healthy population, 5) generate a similar report (using a structural and functional arterial age calculator) for the patients assessing the state of their arteries. In this paper, we present the main characteristics of the CUiiDARTE health informatics development.
authors.affiliation: Physiology Department, School of Medicine, CUiiDARTE, Republic University, Montevideo 11800, Uruguay. dbia@fmed.edu.uy
authors.forename: Daniel Bia
authors.initials: DB
authors.lastname: Santana
authors.forename: Yanina A
authors.initials: YA
authors.lastname: Zócalo
authors.forename: Ignacio Farro
authors.initials: IF
authors.lastname: Ventura
authors.forename: Juan Francisco Torrado
authors.initials: JF
authors.lastname: Arrosa
authors.forename: Lucía
authors.initials: L
authors.lastname: Florio
authors.forename: Ricardo
authors.initials: R
authors.lastname: Lluberas
authors.forename: Ricardo L
authors.initials: RL
authors.lastname: Armentano
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000465:Algorithms; D050197:Atherosclerosis / Q000175:diagnosis* / Q000473:pathology; D002648:Child; D016208:Databases, Factual; D003935:Diagnostic Techniques, Cardiovascular; D042241:Early Diagnosis; D005260:Female; D006801:Humans; D020407:Internet; D008297:Male; D008490:Medical Informatics / Q000379:methods*; D008875:Middle Aged; D012307:Risk Factors