title: Prevalence of anemia among Quebec Cree infants from 2002 to 2007 compared with 1995 to 2000.
abstract: OBJECTIVE
  To determine if screening of infants for anemia at 9 months in the Cree region of Quebec should continue,by comparing the prevalence of anemia in the initial years of screening (1995 to 2000) with prevalence data from infants screened between 2002 and 2007.
  
  
  METHODS
  Comparison of anemia prevalence from 2 cross-sectional surveys. Nonoverlapping 95% CIs were used to determine if results were significantly different.
  
  
  METHODS
  Nine Quebec Cree communities. Participants Infants screened for anemia between 1995 and 2000 (n = 716) or 2002 and 2007 (n = 1325). Main outcome measures Anemia was diagnosed based on hemoglobin concentration. An erythrocyte mean cell volume of less than 71 fL was used as a proxy for iron deficiency.
  
  
  RESULTS
  Hemoglobin concentration among infants screened from 2002 to 2007 was, on average, 7 g/L greater than among infants screened from 1995 to 2000 (mean [standard deviation] 121 [11] g/L vs 114 [11] g/L). The prevalence of anemia (hemoglobin < 110 g/L) from 1995 to 2000 was 31.7% (95% CI 28.3% to 35.1%), but from 2002 to 2007 it was significantly lower at 12.5% (95% CI 10.7% to 14.2%). Using a hemoglobin concentration more specific to iron deficiency anemia (IDA) (hemoglobin < 100 g/L), from 1995 to 2000 7.5% (95% CI 5.6% to 9.4%) of infants had IDA, whereas from 2002 to 2007 only 2.0% (95% CI 1.2% to 2.8%) had IDA. The prevalence of iron deficiency based on mean cell volume declined from 18.3% (95% CI 15.5% to 21.1%) from 1995 to 2000 to 4.2% (95% CI 3.1% to 5.3%) from 2002 to 2007.
  
  
  CONCLUSIONS
  The 12.5% prevalence of anemia (hemoglobin < 110 g/L) among Cree infants from 2002 to 2007 was much lower than the prevalence from 1995 to 2000 but somewhat higher than among nonaboriginal infants (8.0%). The low anemia prevalence among Quebec Cree infants after 2002 suggests that replacing universal screening with targeted screening of higher-risk infants needs to be considered following studies to identify risk factors for anemia.
authors.affiliation: Alberta Institute for Human Nutrition, University of Alberta, Edmonton, Canada. noreen.willows@ualberta.ca
authors.forename: Noreen
authors.initials: N
authors.lastname: Willows
authors.forename: David
authors.initials: D
authors.lastname: Dannenbaum
authors.forename: Sophie
authors.initials: S
authors.lastname: Vadeboncoeur
mesh_terms: D000740:Anemia / Q000097:blood / Q000175:diagnosis / Q000208:ethnology*; D018798:Anemia, Iron-Deficiency / Q000097:blood / Q000175:diagnosis / Q000208:ethnology; D003430:Cross-Sectional Studies; D004909:Erythrocyte Indices; D006454:Hemoglobins / Q000378:metabolism; D006801:Humans; D007198:Indians, North American; D007223:Infant; D008403:Mass Screening; D015995:Prevalence; D011792:Quebec / Q000453:epidemiology
chemical_list: D006454:Hemoglobins