title: Disseminated Cryptococcus with ocular cryptococcoma in a human immunodeficiency virus-negative patient.
abstract: A human immunodeficiency virus-negative 63-year-old male with autoimmune hemolytic anemia presented with decreased vision, photophobia and hearing loss. After initial testing seemed consistent with sarcoidosis, he was found to have disseminated Cryptococcus with a cryptococcoma of the left eye. Treatment with systemic anti-fungal therapy improved the patient's condition.
authors.affiliation: Department of Ophthalmology, School of Medicine, West Virginia University, Morgantown, WV, USA. kreschz@wvuhealthcare.com
authors.forename: Zvi A
authors.initials: ZA
authors.lastname: Kresch
authors.forename: Diego
authors.initials: D
authors.lastname: Espinosa-Heidmann
authors.forename: Tiffany
authors.initials: T
authors.lastname: Harper
authors.forename: G
authors.initials: G
authors.lastname: Jamie Miller
mesh_terms: D000666:Amphotericin B / Q000627:therapeutic use; D000744:Anemia, Hemolytic, Autoimmune / Q000150:complications; D000935:Antifungal Agents / Q000627:therapeutic use; D003453:Cryptococcosis / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D003454:Cryptococcus / Q000302:isolation & purification*; D004359:Drug Therapy, Combination; D015821:Eye Infections, Fungal / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D015725:Fluconazole / Q000627:therapeutic use; D005437:Flucytosine / Q000627:therapeutic use; D018023:HIV Seronegativity; D006801:Humans; D008172:Lung Diseases, Fungal / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D008279:Magnetic Resonance Imaging; D008297:Male; D016921:Meningitis, Fungal / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D008875:Middle Aged; D012008:Recurrence; D012164:Retinal Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D014057:Tomography, X-Ray Computed; D014822:Vitreous Body / Q000382:microbiology
chemical_list: D000935:Antifungal Agents; D000666:Amphotericin B; D015725:Fluconazole; D005437:Flucytosine