title: Transient periodic lateralised epileptiform discharges (PLEDs) following internal carotid artery stenting.
abstract: Background. Periodic lateralised epileptiform discharges (PLEDs) are EEG patterns consisting of periodic or pseudoperiodic unilateral, focal or hemispheric epileptiform discharges at a rate of 1-2 Hz. PLEDs may be triggered by acute brain injuries or systemic metabolic changes such as fever, hyperglycaemia or electrolyte imbalance and may result in disturbance of consciousness and/or neurological deficits. Case report. A 58-year-old female with a history of focal epilepsy and deep brain haematoma presented with acute change in awareness, associated with EEG evidence of PLEDs, three days after a left internal carotid artery stenting procedure. Clinical examination, laboratory testing and MRI were unchanged with respect to pre-stenting investigations. Conclusion. In this patient, PLEDs may have been triggered by local haemodynamic changes due to reperfusion after stenting in a previously damaged brain area.
authors.affiliation: Department of Neurological, Behavioural and Neurosurgical Sciences, Section of Neurological Sciences, University of Siena, Italy.
authors.forename: Daniela
authors.initials: D
authors.lastname: Marino
authors.forename: Giampaolo
authors.initials: G
authors.lastname: Vatti
authors.forename: Alessandra
authors.initials: A
authors.lastname: Rufa
authors.forename: Alessandro
authors.initials: A
authors.lastname: Malandrini
authors.forename: Raffaele
authors.initials: R
authors.lastname: Rocchi
authors.forename: Sandra
authors.initials: S
authors.lastname: Bracco
authors.forename: Rosaria
authors.initials: R
authors.lastname: Buccoliero
authors.forename: Antonio
authors.initials: A
authors.lastname: Federico
mesh_terms: D019917:Blood Vessel Prosthesis Implantation / Q000009:adverse effects*; D001921:Brain / Q000503:physiopathology*; D002343:Carotid Artery, Internal / Q000601:surgery*; D016893:Carotid Stenosis / Q000601:surgery*; D004828:Epilepsies, Partial / Q000209:etiology* / Q000503:physiopathology; D005260:Female; D006801:Humans; D008875:Middle Aged; D015607:Stents