title: [Fertility and pregnancy outcome following invasive management of severe postpartum hemorrhage].
abstract: OBJECTIVE
  Ligation of the internal iliac arteries and embolization of the uterine arteries are two techniques routinely used in the management of postpartum hemorrhage. The objective of this study was to examine the long-term consequences of these techniques on women's subsequent reproductive outcome and subsequent delivery morbidity.
  
  
  METHODS
  Retrospective study including women who underwent ligation and those who underwent embolization, for the treatment of postpartum hemorrhage. We analyzed resumption of menses, fertility, pregnancy and delivery outcome after each treatment.
  
  
  RESULTS
  The study included 85 women who underwent ligation and 90 who had embolization to treat postpartum hemorrhage. No adverse event related to menses, fertility, or pregnancy outcome followed either treatment. However, the rate of recurrent hemorrhage was high: 26% after ligation and 39% after embolization. All recurrences were treated medically in the ligation group, but in the embolization group, 42% (five of 12 patients) required invasive treatment and 33% (four patients) transfusions.
  
  
  CONCLUSIONS
  From the perspective of subsequent menses, fertility and pregnancy outcome, both ligation and embolization are safe procedures for the management of postpartum hemorrhage. However, our results showed a high risk of recurrent postpartum hemorrhage after both treatments. Recurrences seemed more serious after the latter.
authors.affiliation: Service de gynécologie-obstétrique, hôpital Bicêtre, Assistance publique-Hôpitaux de Paris (AP-HP), 82 rue du Général-Leclerc, Le-Kremlin-Bicêtre, France. perrine.capmas@bct.aphp.com
authors.forename: P
authors.initials: P
authors.lastname: Capmas
authors.forename: O
authors.initials: O
authors.lastname: Picone
authors.forename: D
authors.initials: D
authors.lastname: Musset
authors.forename: R
authors.initials: R
authors.lastname: Frydman
authors.forename: H
authors.initials: H
authors.lastname: Fernandez
mesh_terms: D001803:Blood Transfusion; D004621:Embolization, Therapeutic; D005260:Female; D005298:Fertility; D006801:Humans; D007083:Iliac Artery / Q000601:surgery; D008026:Ligation; D006473:Postpartum Hemorrhage / Q000453:epidemiology / Q000601:surgery / Q000628:therapy*; D011247:Pregnancy; D011256:Pregnancy Outcome; D012008:Recurrence; D012189:Retrospective Studies; D055988:Uterine Artery