title: Transition-metal-free intramolecular N-arylations.
abstract: N-Substituted phenoxazines and related aza analogs have been prepared from N-acetylated aryloxy anilides by transition-metal-free, base-catalyzed cyclization reactions. In the presence of a mixture of 10 mol % of N,N'-dimethylethylenediamine (DMEDA) and 2 equiv of K(2)CO(3) in toluene at 135 °C the products are obtained in high yields.
authors.affiliation: Institute of Organic Chemistry, RWTH Aachen University, Landoltweg1, D-52074 Aachen, Germany.
authors.forename: Isabelle
authors.initials: I
authors.lastname: Thomé
authors.forename: Carsten
authors.initials: C
authors.lastname: Bolm
mesh_terms: D001372:Aza Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D003500:Cyclization; D005029:Ethylenediamines / Q000737:chemistry*; D015394:Molecular Structure; D010078:Oxazines / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D001372:Aza Compounds; D005029:Ethylenediamines; D010078:Oxazines; C027450:dimethylethylenediamine; C039203:phenoxazine