title: Surgical treatment of glioblastoma multiforme localized in the motor area of the brain using the technique of cortical electrostimulation.
abstract: OBJECTIVE
  Glioblastoma multiforme in the motor area is the surgical challenge because of the need for more radical resection in order to extend the life of the patient, and the risk that radicalism could lead to additional neurological deficit.
  
  
  METHODS
  We present series of 26 patients with glioblastoma multiforme localized in and around the motor area, who were hospitalized from October 2004 to February 2009. During all operations, we conducted electrostimulation display area of the brain, to the anatomical location of M1 segment of the motor cortex.
  
  
  RESULTS
  Distance of the central sulcus in relation to the coronary suture, measured by magnetic resonance imaging (MRI) was 18.38 mm ± 9.564 mm. The volume of electricity required for a motor response was mean 8.79 ± 1.484 mA, with increasing distance from the coronary suture the amperage required to explicit motor responses decreased. The difference (mm) between the distance from the coronary suture measured using MRI and distances measured electrostimulation smaller and power consumption was less (F = 13.285, p < 0.01).
  
  
  CONCLUSIONS
  The method of cortical cerebral cortex electrostimulation is simple and safe method and a binding protocol to the patient safe operation glioblastoma multiforme localized in the motor area of the brain.
authors.affiliation: Clinical Centre of Serbia, Institute for Neurosurgery, Belgrade, Serbia, Yugoslavia. neurobog@beotel.rs
authors.forename: Vojislav
authors.initials: V
authors.lastname: Bogosavljevic
authors.forename: Goran
authors.initials: G
authors.lastname: Tasic
authors.forename: Branislav
authors.initials: B
authors.lastname: Nestorovic
authors.forename: Vladimir
authors.initials: V
authors.lastname: Jovanovic
authors.forename: Miodrag
authors.initials: M
authors.lastname: Rakic
authors.forename: Miroslav
authors.initials: M
authors.lastname: Samardzic
mesh_terms: D000328:Adult; D000368:Aged; D001931:Brain Mapping / Q000379:methods*; D004558:Electric Stimulation / Q000379:methods*; D005909:Glioblastoma / Q000473:pathology* / Q000601:surgery*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D009044:Motor Cortex / Q000033:anatomy & histology / Q000502:physiology*; D011183:Postoperative Complications / Q000517:prevention & control; D011300:Preoperative Care / Q000379:methods*