title: Choroidal metastasis as the sole initial presentation of metastatic lung cancer.
abstract: Choroidal metastasis as an initial presenting feature of metastatic lung cancer is exceedingly rare. External beam radiotherapy (EBRT) is an effective and widely accepted therapeutic modality. However, data addressing the effectiveness of other treatment strategies is limited. We present a patient with choroidal metastases secondary to lung cancer and review the relevant literature. A 25-year-old male presented with deterioration of vision. His evaluation revealed bilateral choroidal metastasis secondary to adeno- carcinoma of the lung. Unfortunately, his vision continued to deteriorate despite treatment with EBRT and chemotherapy. Choroidal metastasis as an initial presentation of metastatic lung cancer is exceedingly rare, as only 30 cases have been reported. EBRT and systemic chemotherapy are effective therapeutic modalities. This case report could prove helpful to clinicians faced with a similar exceedingly rare scenario.
authors.affiliation: Department of Internal Medicine, King Hussein Cancer Center, Amman, Jordan. ssalah@khcc.jo
authors.forename: S
authors.initials: S
authors.lastname: Salah
authors.forename: J
authors.initials: J
authors.lastname: Khader
authors.forename: Y
authors.initials: Y
authors.lastname: Yousef
authors.forename: A
authors.initials: A
authors.lastname: Salem
authors.forename: M
authors.initials: M
authors.lastname: Al-Hussaini
authors.forename: R
authors.initials: R
authors.lastname: Al-Asady
mesh_terms: D000230:Adenocarcinoma / Q000556:secondary* / Q000628:therapy; D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D059248:Chemoradiotherapy; D002830:Choroid Neoplasms / Q000556:secondary* / Q000628:therapy; D002945:Cisplatin / Q000008:administration & dosage; D000077143:Docetaxel; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology*; D008297:Male; D009362:Neoplasm Metastasis; D043823:Taxoids / Q000008:administration & dosage
chemical_list: D043823:Taxoids; D000077143:Docetaxel; D002945:Cisplatin