title: Effects of selenium supplementation on the natural course of autoimmune thyroiditis: a short review.
abstract: Selenium (Se) is an important element that exerts its effects on the selenoproteins. It is an essential component of the glutathione peroxidase enzymes, which have anti-oxidant and anti-inflammatory properties, and a component of iodothyronine selenodeiodinases, which catalyze the extrathyroid production of T3 from T4. Se is important to several aspects of thyroid homeostasis and may influence the natural course of thyroid diseases such as autoimmune thyroiditis (AIT). This review analyzes the effects of Se supplementation in patients with AIT, based on the studies published on this issue to date.
authors.affiliation: Department of Medical and Surgical Sciences, University of Padua, Via Ospedale n.105, Padua, Italy.
authors.forename: D
authors.initials: D
authors.lastname: Petricca
authors.forename: D
authors.initials: D
authors.lastname: Nacamulli
authors.forename: C
authors.initials: C
authors.lastname: Mian
authors.forename: F
authors.initials: F
authors.lastname: Mantero
authors.forename: E
authors.initials: E
authors.lastname: Cavedon
authors.forename: M E
authors.initials: ME
authors.lastname: Girelli
authors.forename: C
authors.initials: C
authors.lastname: Betterle
mesh_terms: D000818:Animals; D019587:Dietary Supplements; D018450:Disease Progression; D006801:Humans; D016032:Randomized Controlled Trials as Topic / Q000379:methods; D012643:Selenium / Q000627:therapeutic use*; D013967:Thyroiditis, Autoimmune / Q000188:drug therapy* / Q000473:pathology*; D016896:Treatment Outcome
chemical_list: D012643:Selenium