title: Management of opioid substitution therapy during medical intervention.
abstract: Opioid substitution therapy (OST) for opioid dependence is common, and injection drug users have significant medical and psychiatric comorbidity. Many physicians will encounter OST patients in their usual practice. This article provides guidance on management of common clinical problems in this population, including OST management in hepatic failure, respiratory disease, pain management and potential drug interactions.
authors.affiliation: Drug Health Services, Concord Repatriation General Hospital, Drug Health Services, Royal Prince Alfred Hospital, and University of Sydney, Discipline of Addiction Medicine, Sydney, New South Wales, Australia. bmurnion@med.usyd.edu.au
authors.forename: B
authors.initials: B
authors.lastname: Murnion
mesh_terms: D000700:Analgesics / Q000627:therapeutic use; D001315:Australia / Q000453:epidemiology; D002047:Buprenorphine / Q000009:adverse effects / Q000494:pharmacology / Q000627:therapeutic use; D015897:Comorbidity; D004347:Drug Interactions; D005260:Female; D006801:Humans; D008107:Liver Diseases / Q000453:epidemiology; D001523:Mental Disorders / Q000453:epidemiology / Q000628:therapy; D008691:Methadone / Q000009:adverse effects / Q000494:pharmacology / Q000627:therapeutic use; D009270:Naloxone / Q000009:adverse effects / Q000494:pharmacology / Q000627:therapeutic use; D058850:Opiate Substitution Treatment / Q000379:methods*; D010146:Pain / Q000188:drug therapy; D059408:Pain Management; D010166:Palliative Care; D019338:Polypharmacy; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy; D012131:Respiratory Insufficiency / Q000139:chemically induced; D019966:Substance-Related Disorders / Q000453:epidemiology; D014777:Virus Diseases / Q000453:epidemiology
chemical_list: D000700:Analgesics; D009270:Naloxone; D002047:Buprenorphine; D008691:Methadone