title: Metal-free TEMPO-catalyzed oxidative C-C bond formation from Csp3-H bonds using molecular oxygen as the oxidant.
abstract: An efficient TEMPO-catalyzed oxidative C-C bond formation with two Csp(3)-H bonds using molecular oxygen as the oxidant has been developed. The novel transformation provides a new strategy for the TEMPO-O(2) catalysis to construct C-C bonds. The advantages of this method include: (1) relatively mild and neutral conditions; (2) simplicity and safety of operation; (3) a stoichiometric amount of dangerous oxidants, any transition metals, additives, even solvent, is not required.
authors.affiliation: State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Xue Yuan Rd. 38, Beijing 100191, China.
authors.forename: Bo
authors.initials: B
authors.lastname: Zhang
authors.forename: Yuxin
authors.initials: Y
authors.lastname: Cui
authors.forename: Ning
authors.initials: N
authors.lastname: Jiao
mesh_terms: D002244:Carbon / Q000737:chemistry*; D002384:Catalysis; D006859:Hydrogen / Q000737:chemistry*; D016877:Oxidants / Q000737:chemistry*; D010084:Oxidation-Reduction; D010100:Oxygen / Q000737:chemistry*; D010880:Piperidines / Q000737:chemistry*
chemical_list: C528764:2,2,6,6-tetramethyl-1-piperidine; D016877:Oxidants; D010880:Piperidines; D002244:Carbon; D006859:Hydrogen; D010100:Oxygen