title: Behavioral bioassays and their uses in Tetrahymena.
abstract: The swimming behaviors of Tetrahymena can be used in sensitive behavioral bioassays for estimating the effects of drugs, mutations, and other conditions on the physiological state of the cell. These assays can be used in both forward and reverse genetic approaches to help understand cellular functions from genotype to phenotype.
authors.affiliation: Department of Biological Sciences, University at Buffalo, Amherst, NY, USA.
authors.forename: Todd M
authors.initials: TM
authors.lastname: Hennessey
authors.forename: Thomas J
authors.initials: TJ
authors.lastname: Lampert
mesh_terms: D000222:Adaptation, Physiological; D001681:Biological Assay / Q000379:methods*; D002470:Cell Survival; D002633:Chemotaxis; D002923:Cilia / Q000502:physiology; D055724:Electrophysiological Phenomena; D005838:Genotype; D007091:Image Processing, Computer-Assisted; D009154:Mutation; D010641:Phenotype; D011188:Potassium / Q000494:pharmacology; D012098:Reproduction; D013550:Swimming / Q000502:physiology*; D013768:Tetrahymena / Q000187:drug effects / Q000254:growth & development / Q000502:physiology*; D013997:Time Factors
chemical_list: D011188:Potassium