title: Study on serum cytokine levels in posttraumatic stress disorder patients.
abstract: OBJECTIVE
  To evaluate serum IL-2, IL-4, IL-6, IL-8, IL-10 and TNF-α levels in posttraumatic stress disorder (PTSD) patients.
  
  
  METHODS
  We utilized ELISA technology to examine cytokines such as IL-2, IL-4, IL-6, IL-8, IL-10 and TNF-α in serum from 50 well-characterized individuals with a primary DSM-IV PTSD diagnosis, and 50 age- and gender-matched healthy controls. We conservatively employed a Mann-Whitney U testing.
  
  
  RESULTS
  Individuals with primary PTSD had significantly elevated peripheral cytokine levels for all 6 different cytokines compared to age- and gender-matched healthy controls (all P<0.01).
  
  
  CONCLUSIONS
  These findings suggest that a generalized inflammatory state may be present in individuals with PTSD.
authors.affiliation: People's Hospital of Hainan Province, Hainan Medical College. g2002m@163.com
authors.forename: Min
authors.initials: M
authors.lastname: Guo
authors.forename: Tao
authors.initials: T
authors.lastname: Liu
authors.forename: Jun-Cheng
authors.initials: JC
authors.lastname: Guo
authors.forename: Xiang-Ling
authors.initials: XL
authors.lastname: Jiang
authors.forename: Feng
authors.initials: F
authors.lastname: Chen
authors.forename: Yun-Suo
authors.initials: YS
authors.lastname: Gao
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D007378:Interleukins / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D013313:Stress Disorders, Post-Traumatic / Q000097:blood*; D014409:Tumor Necrosis Factor-alpha / Q000378:metabolism*
chemical_list: D007378:Interleukins; D014409:Tumor Necrosis Factor-alpha