title: Palladium-catalyzed C-N cross coupling of sulfinamides and aryl halides.
abstract: The palladium-catalyzed C-N cross coupling of sulfinamides and aryl halides is reported. In the presence of Pd(2)(dba)(3), tBuXPhos, NaOH, and a small amount of water, the C-N cross coupling of chiral tert-butanesulfinamide and aryl halides was accomplished to give N-aryl tert-butanesulfinamide without racemization, and the coupling of racemic p-toluenesulfinamide smoothly afforded N-aryl p-toluenesulfinamides. 2-Bromopyridine was also suitable for the coupling. Addition of a small amount of water to the catalytic system was of importance to obtain high yields.
authors.affiliation: Institute of Green Catalysis and Synthesis, College of Materials and Chemistry & Chemical Engineering, Chengdu University of Technology, Chengdu 610059, China.
authors.forename: Xiaofei
authors.initials: X
authors.lastname: Sun
authors.forename: Xingzhao
authors.initials: X
authors.lastname: Tu
authors.forename: Chuan
authors.initials: C
authors.lastname: Dai
authors.forename: Xiaoping
authors.initials: X
authors.lastname: Zhang
authors.forename: Binbin
authors.initials: B
authors.lastname: Zhang
authors.forename: Qingle
authors.initials: Q
authors.lastname: Zeng