title: Potential of Novel EPO Derivatives in Limb Ischemia.
abstract: Erythropoietin (EPO) has tissue-protective properties, but it increases the risk of thromboembolism by raising the haemoglobin concentration. New generation of EPO derivatives is tissue protective without the haematopoietic side effects. Preclinical studies have demonstrated their effectiveness and safety. This paper summarizes the development in EPO derivatives with emphasis on their potential use in critical limb ischaemia.
authors.affiliation: Vascular Unit, Division of Surgery and Interventional Science, Royal Free Hospital, University College London (Royal Free Campus), Pond Street, London NW3 2QG, UK.
authors.forename: Dhiraj
authors.initials: D
authors.lastname: Joshi
authors.forename: Janice
authors.initials: J
authors.lastname: Tsui
authors.forename: Rebekah
authors.initials: R
authors.lastname: Yu
authors.forename: Xu
authors.initials: X
authors.lastname: Shiwen
authors.forename: Sadasivam
authors.initials: S
authors.lastname: Selvakumar
authors.forename: David J
authors.initials: DJ
authors.lastname: Abraham
authors.forename: Daryll M
authors.initials: DM
authors.lastname: Baker