title: Treatment of mild, moderate, and severe onychomycosis using 870- and 930-nm light exposure: some follow-up observations at 270 days.
abstract: We have previously reported the results of a clinical trial in which the Noveon laser was used to treat onychomycosis. In the 180-day follow-up therein it was noted that positive clinical impact was demonstrable by a clearly measurable decrease in positive fungal culture and a concomitant decrease in positive microscopy with periodic acid-Schiff-stained nail scrapings. Review of 270-day mycological data, which are now available, confirmed that there was further decrease in both measures. Indeed, 38% of the treated population had negative culture and microscopy, qualifying as "mycological cures." These mycological cures occurred in cases categorized as mild, moderate, and even severe disease.
authors.affiliation: Division of Podiatric Surgery, Cambridge Health Alliance, Cambridge, MA, USA. alandsman@cha.harvard.edu
authors.forename: Adam S
authors.initials: AS
authors.lastname: Landsman
authors.forename: Alan H
authors.initials: AH
authors.lastname: Robbins
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D005533:Foot Dermatoses / Q000532:radiotherapy*; D006801:Humans; D028022:Low-Level Light Therapy / Q000379:methods*; D008297:Male; D008875:Middle Aged; D014009:Onychomycosis / Q000532:radiotherapy*; D012720:Severity of Illness Index; D055815:Young Adult