title: [Neuromodulation in the treatment of hand's scars].
abstract: OBJECTIVE
  In the present study, we investigated effects of a local anesthetic, in the treatment of pathologic scars.
  
  
  METHODS
  this retrospective report describes our experience with 97 patients who underwent lidocaine 2% injections in surgical scars of the hand. The results were evaluated using 4 parameters: cutaneous structure, pain, thikness and colour of the scar.
  
  
  RESULTS
  The mean outcome was the pain control. 2 out of 97 showed a 100% improvement in all the parameters. In 95 of 97 patients the improvement was between 60-100%.
  
  
  CONCLUSIONS
  Lidocaine controls different pathways of inflammation. Flogosis is the first phase of cicatrization and so lidocaine could be used in the treatment of pathologic scars. A previous study confirms the role of lidocaine, injected to control the pillar pain in the carpal tunnel's surgery in the improvement of scars.
  
  
  CONCLUSIONS
  Lidocaine, as neuromodulation treatment, acts on inflammation, temperature, perfusion and partial pressure of oxygen.
authors.affiliation: Department of Dermatology and Plastic, Reconstructive and Aesthetic Surgery, University of Rome La Sapienza Policlinico Umberto I, Rome, Italy.
authors.forename: Anna Maria
authors.initials: AM
authors.lastname: Spagnoli
authors.forename: Pasquale
authors.initials: P
authors.lastname: Fino
authors.forename: Paolo
authors.initials: P
authors.lastname: Fioramonti
authors.forename: Federico
authors.initials: F
authors.lastname: Corrias
authors.forename: Federico
authors.initials: F
authors.lastname: Lo Torto
authors.forename: Nicolò
authors.initials: N
authors.lastname: Scuderi
mesh_terms: D000779:Anesthetics, Local / Q000008:administration & dosage*; D002921:Cicatrix / Q000628:therapy*; D005260:Female; D006225:Hand; D006801:Humans; D015552:Injections, Intralesional; D008012:Lidocaine / Q000008:administration & dosage*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies
chemical_list: D000779:Anesthetics, Local; D008012:Lidocaine