title: Endovascular treatment of acute ischemic stroke: current indications.
abstract: Endovascular stroke therapy is an effective means of achieving reperfusion in stroke patients with proximal cerebral artery occlusions. However, current guideline recommendations express uncertainty regarding the clinical efficacy of catheter-based treatments, given the lack of supportive trial data. A critical problem is that it remains unclear which patients will benefit from endovascular therapy. As such, patient selection is likely highly variable in clinical practice. This article will review the existing data to discuss the clinical and imaging factors that are relevant to patient outcomes, and which may be used to guide endovascular treatment decisions. Anterior circulation strokes represent the primary focus of this review.
authors.affiliation: Division of Interventional Neuroradiology and Endovascular Neurosurgery, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA. ajyoo@partners.org
authors.forename: Albert J
authors.initials: AJ
authors.lastname: Yoo
authors.forename: Zeshan A
authors.initials: ZA
authors.lastname: Chaudhry
authors.forename: Thabele M
authors.initials: TM
authors.lastname: Leslie-Mazwi
authors.forename: Ronil V
authors.initials: RV
authors.lastname: Chandra
authors.forename: Joshua A
authors.initials: JA
authors.lastname: Hirsch
authors.forename: Ramon Gilberto
authors.initials: RG
authors.lastname: González
authors.forename: Claus Z
authors.initials: CZ
authors.lastname: Simonsen
mesh_terms: D002545:Brain Ischemia / Q000150:complications / Q000000981:diagnostic imaging / Q000601:surgery*; D057510:Endovascular Procedures / Q000295:instrumentation / Q000379:methods* / Q000639:trends*; D019317:Evidence-Based Medicine; D006801:Humans; D011859:Radiography; D020521:Stroke / Q000000981:diagnostic imaging / Q000209:etiology / Q000601:surgery*