title: Biological, clinical, and psychosocial correlates at the interface of cancer and aging research.
abstract: In September 2010, the Cancer and Aging Research Group, in collaboration with the National Cancer Institute and the National Institute on Aging, conducted the first of three planned conferences to discuss research methodology to generate the highest quality research in older adults with cancer and then disseminate these findings among those working in the fields of cancer and aging. Conference speakers discussed the current level of research evidence in geriatric oncology, outlined the current knowledge gaps, and put forth principles for research designs and strategies that would address these gaps within the next 10 years. It was agreed that future oncology research trials that enroll older adults should include: (1) improved standardized geriatric assessment of older oncology patients, (2) substantially enhanced biological assessment of older oncology patients, (3) specific trials for the most vulnerable and/or those older than 75 years, and (4) research infrastructure that specifically targets older adults and substantially strengthened geriatrics and oncology research collaborations. This initial conference laid the foundation for the next two meetings, which will address the research designs and collaborations needed to enhance therapeutic and intervention trials in older adults with cancer.
authors.affiliation: Department of Medical Oncology and Therapeutics Research, City of Hope, 1500 E Duarte Rd, Duarte, CA 91010, USA.
authors.forename: William
authors.initials: W
authors.lastname: Dale
authors.forename: Supriya G
authors.initials: SG
authors.lastname: Mohile
authors.forename: Basil A
authors.initials: BA
authors.lastname: Eldadah
authors.forename: Edward L
authors.initials: EL
authors.lastname: Trimble
authors.forename: Richard L
authors.initials: RL
authors.lastname: Schilsky
authors.forename: Harvey J
authors.initials: HJ
authors.lastname: Cohen
authors.forename: Hyman B
authors.initials: HB
authors.lastname: Muss
authors.forename: Kenneth E
authors.initials: KE
authors.lastname: Schmader
authors.forename: Betty
authors.initials: B
authors.lastname: Ferrell
authors.forename: Martine
authors.initials: M
authors.lastname: Extermann
authors.forename: Susan G
authors.initials: SG
authors.lastname: Nayfield
authors.forename: Arti
authors.initials: A
authors.lastname: Hurria
mesh_terms: D026683:Advisory Committees; D000367:Age Factors; D000368:Aged; D000375:Aging / Q000378:metabolism / Q000523:psychology; D035843:Biomedical Research / Q000639:trends; D002986:Clinical Trials as Topic / Q000639:trends*; D016330:Frail Elderly; D015577:Geriatric Assessment; D006299:Health Services for the Aged; D006801:Humans; D008875:Middle Aged; D009369:Neoplasms / Q000378:metabolism* / Q000523:psychology*; D012107:Research Design; D014481:United States