title: Neutrophil CD64 as a diagnostic marker in neonatal sepsis.
abstract: We assessed neutrophil CD64 as a diagnostic marker for neonatal sepsis. For early-onset sepsis, the CD64 index with a cut-point value of 2.38 had sensitivity, specificity and negative predictive values of 100%, 68% and 100%, respectively. For late-onset sepsis, the respective values were 3.62, 75%, 77% and 96%. Neutrophil CD64 index can be incorporated as a valuable marker for excluding neonatal sepsis.
authors.affiliation: Division of Perinatal Medicine, Department of Pediatrics, Yale University School of Medicine, New Haven, CT 06520, USA.
authors.forename: Iris
authors.initials: I
authors.lastname: Streimish
authors.forename: Matthew
authors.initials: M
authors.lastname: Bizzarro
authors.forename: Veronika
authors.initials: V
authors.lastname: Northrup
authors.forename: Chao
authors.initials: C
authors.lastname: Wang
authors.forename: Sara
authors.initials: S
authors.lastname: Renna
authors.forename: Nancy
authors.initials: N
authors.lastname: Koval
authors.forename: Fang-Yong
authors.initials: FY
authors.lastname: Li
authors.forename: Richard
authors.initials: R
authors.lastname: Ehrenkranz
authors.forename: Henry M
authors.initials: HM
authors.lastname: Rinder
authors.forename: Vineet
authors.initials: V
authors.lastname: Bhandari
mesh_terms: D015415:Biomarkers / Q000097:blood; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D009504:Neutrophils / Q000737:chemistry*; D011237:Predictive Value of Tests; D017452:Receptors, IgG / Q000032:analysis*; D012680:Sensitivity and Specificity; D018805:Sepsis / Q000175:diagnosis* / Q000473:pathology*
chemical_list: D015415:Biomarkers; D017452:Receptors, IgG