title: Conflicts among multinational ethical and scientific standards for clinical trials of therapeutic interventions.
abstract: Utilizing a sorted compendium of international clinical trial standards, investigators identified 15 conflicts among ethical and methodological guidance. Analysis distinguishes interpretational issues, lack of clarity, and contradiction as factors to be addressed if international trial guidance is to be improved.
authors.affiliation: Baylor College of Medicine Center for Medical Ethics and Health Policy, Houston Texas, USA.
authors.forename: Jacob M
authors.initials: JM
authors.lastname: Kolman
authors.forename: Nelda P
authors.initials: NP
authors.lastname: Wray
authors.forename: Carol M
authors.initials: CM
authors.lastname: Ashton
authors.forename: Danielle M
authors.initials: DM
authors.lastname: Wenner
authors.forename: Anna F
authors.initials: AF
authors.lastname: Jarman
authors.forename: Baruch A
authors.initials: BA
authors.lastname: Brody
mesh_terms: D002986:Clinical Trials as Topic / Q000941:ethics / Q000592:standards*; D006801:Humans; D038622:Internationality; D018579:Patient Selection / Q000941:ethics; D035703:Therapies, Investigational