title: Multi-central clinical research into treating 80 cases of chronic thrombocytopenia with qi-supplementing and yin-nourishing therapy and western medicine.
abstract: OBJECTIVE
  To probe the effects of qi-supplementing and yin-nourishing therapy (blood-increasing decoction and blood generating powder) on chronic thrombocytopenia.
  
  
  METHODS
  Two hundred patients with chronic thrombocytopenia were randomly divided into control (n = 100) and test groups (n = 100) with Amino-polypeptide as a basic treatment for both. Test group patients consumed a blood-increasing decoction and blood-generating powder for 1-3 months. Improvements in platelet counts and TCM syndrome were observed.
  
  
  RESULTS
  One hundred and sixty-four (80 in the test group and 84 in the control group) of 189 total participants were treated for 3 months. The total effective rate in improving TCM syndrome was 95.00% in the test group and 79.76% in the control group (P < 0.05). There was significant difference (P < 0.05) in the accumulated score of TCM syndrome between the two groups treated at different time points. The total effective rate of platelet counts was 86.25% in the test group and 59.52% in the control group (P < 0.05). There was a significant difference in platelet counts before and after treatment in the two groups (P < 0.05). There was no significant differences in platelet count between the two groups treated for 1-2 months; however, a significant difference was found between the two groups after treatment for 3 months (P < 0.05).
  
  
  CONCLUSIONS
  After a 3-month treatment of chronic thrombocytopenia patients with qi-supplementing and yin-nourishing therapy, TCM syndrome was improved and platelet counts increased with no obvious side effects, and the quality of life of the participants was enhanced with noticeable long-term curative effects.
authors.affiliation: The First Hospital Affiliated to Zhejiang TCM University, Hangzhou 310006, China. zyhblood@163.com
authors.forename: Yu-Hong
authors.initials: YH
authors.lastname: Zhou
authors.forename: Ke-Ming
authors.initials: KM
authors.lastname: Wei
authors.forename: Lv-Yuan
authors.initials: LY
authors.lastname: He
authors.forename: Xue-Mei
authors.initials: XM
authors.lastname: Sun
authors.forename: Ke-Ding
authors.initials: KD
authors.lastname: Shao
authors.forename: Bing-Mu
authors.initials: BM
authors.lastname: Fang
authors.forename: Yi-Ping
authors.initials: YP
authors.lastname: Shen
authors.forename: Bao-Dong
authors.initials: BD
authors.lastname: Ye
authors.forename: Jian-Ping
authors.initials: JP
authors.lastname: Shen
authors.forename: Sheng-Yun
authors.initials: SY
authors.lastname: Lin
authors.forename: Zhi-Lu
authors.initials: ZL
authors.lastname: Chen
authors.forename: Gang-Li
authors.initials: GL
authors.lastname: Cai
authors.forename: Jian
authors.initials: J
authors.lastname: Chen
authors.forename: Yan-Ting
authors.initials: YT
authors.lastname: Gao
authors.forename: Xiao-Qiu
authors.initials: XQ
authors.lastname: Wang
authors.forename: Jia-Jia
authors.initials: JJ
authors.lastname: Zhu
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010455:Peptides / Q000627:therapeutic use; D010976:Platelet Count; D019413:Qi; D013921:Thrombocytopenia / Q000097:blood / Q000188:drug therapy*; D016710:Yin Deficiency / Q000097:blood / Q000188:drug therapy*; D055815:Young Adult
chemical_list: D004365:Drugs, Chinese Herbal; D010455:Peptides