title: [Locomotive syndrome and frailty. Recent advances in sarcopenia research].
abstract: Recently, the European Working Group on Sarcopenia in Older People (EWGSOP) has developed a practical definition of sarcopenia, which is the presence of both low muscle mass + low muscle function (strength or performance) . Several studies have shown that sarcopenia might result from low levels of testosterone or vitamin D. Aging-associated chronic inflammation also plays a role. However, effective treatment for sacropenia has not been established so far, thus further basic and clinical studies are essential.
authors.affiliation: Geriatric Medicine and Educational Center, University of Tokyo, Japan.
authors.forename: Masato
authors.initials: M
authors.lastname: Eto
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002908:Chronic Disease; D016330:Frail Elderly; D006801:Humans; D007249:Inflammation / Q000150:complications; D053580:Muscle Strength; D055948:Sarcopenia / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology; D013739:Testosterone / Q000172:deficiency; D014808:Vitamin D Deficiency / Q000150:complications
chemical_list: D013739:Testosterone