title: [Evaluation of the concordance between guidelines and transfusion practices in neonatal intensive care units].
abstract: OBJECTIVE
  To assess the concordance rate between the prescriptions of blood products and Afssaps guidelines for transfusion practices in neonatology.
  
  
  METHODS
  Retrospective monocentric study.
  
  
  METHODS
  Children transfused in the neonatology intensive care units in the Universitary Hospital of Rouen were included. Concordance rates between transfusion prescriptions, delivered and transfused products and the Afssaps guidelines were assessed. Any additional costs resulting from a theoretical discordance was also assessed.
  
  
  RESULTS
  In 2006, 380 PSL were administered to 168 newborn children (NBC). Packed red blood cells (PRBC) represented the most often transfused products (n=290, 76%). Fifty packed platelets (PP) were transfused (13% of the blood products) and 41 fresh frozen plasmas (11%). Overall concordance rate between the Afssaps guidelines and the prescriptions was 64.9%. In 35.1% of cases, the prescription was excessive, compared to the recommendations. Excessive transfusion represented a total of 27,307 euros.
  
  
  CONCLUSIONS
  Global concordance's rate between the guidelines and the prescriptions is fairly well. PRBC are the most blood product transfused. Excessive transfusions related to this concordance rate are leading to important theoretical costs. New informations to the guidelines are warranted to improve transfusional practices in this institution.
authors.affiliation: Département d'anesthésie-réanimation, CHU Charles-Nicolle, 1, rue de Germont, 76031 Rouen cedex, France. vincentroyon@hotmail.com
authors.forename: V
authors.initials: V
authors.lastname: Royon
authors.forename: C
authors.initials: C
authors.lastname: Lardennois
authors.forename: I
authors.initials: I
authors.lastname: Maréchal
authors.forename: B
authors.initials: B
authors.lastname: Dureuil
authors.forename: S
authors.initials: S
authors.lastname: Marret
authors.forename: V
authors.initials: V
authors.lastname: Laudenbach
mesh_terms: D016913:Blood Component Transfusion; D001803:Blood Transfusion / Q000191:economics / Q000379:methods / Q000592:standards*; D017707:Erythrocyte Transfusion / Q000592:standards / Q000706:statistics & numerical data; D005260:Female; D019983:Guideline Adherence / Q000191:economics / Q000706:statistics & numerical data*; D006400:Hematocrit; D006801:Humans; D007231:Infant, Newborn; D007363:Intensive Care Units, Neonatal / Q000191:economics / Q000458:organization & administration*; D008297:Male; D010949:Plasma; D017713:Platelet Transfusion / Q000592:standards / Q000706:statistics & numerical data; D012189:Retrospective Studies