title: New advances in juvenile spondyloarthritis.
abstract: Juvenile spondyloarthritis (SpA) is a distinct disease to adult SpA, and usually manifests as peripheral arthritis and enthesitis. Importantly, many patients with juvenile SpA continue to be at risk of developing ankylosing spondylitis during their disease course. In this Review, the classification and diagnostic criteria, clinical manifestations and treatment guidelines for juvenile SpA will be discussed. Advances in the diagnosis of and management strategies for juvenile SpA will lead to earlier recognition, appropriate treatment and improved rates of inactive disease, which should lead to improved patient outcomes and quality of life.
authors.affiliation: Division of Rheumatology, The Hospital for Sick Children, 555 University Avenue, University of Toronto, Toronto, ON, M5G 1X8, Canada. shirley.tse@sickkids.ca
authors.forename: Shirley M L
authors.initials: SM
authors.lastname: Tse
authors.forename: Ronald M
authors.initials: RM
authors.lastname: Laxer
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D017668:Age of Onset; D001688:Biological Products / Q000627:therapeutic use; D002648:Child; D003131:Combined Modality Therapy; D003952:Diagnostic Imaging / Q000379:methods* / Q000639:trends; D018450:Disease Progression; D042241:Early Diagnosis; D005260:Female; D005544:Forecasting; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D008991:Monitoring, Physiologic / Q000379:methods; D017410:Practice Guidelines as Topic; D011379:Prognosis; D011856:Radiographic Image Enhancement; D012008:Recurrence; D018570:Risk Assessment; D012446:Sacroiliac Joint / Q000473:pathology; D025241:Spondylarthritis / Q000175:diagnosis* / Q000453:epidemiology / Q000628:therapy*; D013167:Spondylitis, Ankylosing / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy; D014409:Tumor Necrosis Factor-alpha / Q000037:antagonists & inhibitors*; D018608:Ultrasonography, Doppler / Q000379:methods; D051598:Whole Body Imaging / Q000379:methods; D055815:Young Adult
chemical_list: D001688:Biological Products; D014409:Tumor Necrosis Factor-alpha