title: Tumor necrosis factor-α inhibitor use is not associated with lipid changes in rheumatoid arthritis.
abstract: OBJECTIVE
  To determine the association of use of tumor necrosis factor-α (TNF-α) inhibitors with differences in lipid levels in patients with rheumatoid arthritis (RA).
  
  
  METHODS
  We studied 807 patients with incident RA to compare differences in lipid levels in TNF-α inhibitor users versus nonusers, with adjustment for relevant covariables.
  
  
  RESULTS
  TNF-α inhibitor use was not associated with differences in levels of low-density lipoprotein (LDL), high-density lipoprotein (HDL), total cholesterol (TC), triglycerides, LDL:HDL, or TC:HDL compared to nonusers.
  
  
  CONCLUSIONS
  Use of TNF-α inhibitor was not associated with differences in lipid levels in patients with RA.
authors.affiliation: Department of Rheumatology, Geisinger Health System, Danville, Pennsylvania 17822, USA. abili1@geisinger.edu
authors.forename: Androniki
authors.initials: A
authors.lastname: Bili
authors.forename: Stephanie J
authors.initials: SJ
authors.lastname: Morris
authors.forename: Jennifer A
authors.initials: JA
authors.lastname: Sartorius
authors.forename: H Les
authors.initials: HL
authors.lastname: Kirchner
authors.forename: Jana L
authors.initials: JL
authors.lastname: Antohe
authors.forename: Sorina
authors.initials: S
authors.lastname: Dancea
authors.forename: Mary Chester
authors.initials: MC
authors.lastname: Wasko
mesh_terms: D000368:Aged; D018501:Antirheumatic Agents / Q000627:therapeutic use; D001172:Arthritis, Rheumatoid / Q000097:blood* / Q000188:drug therapy*; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D015331:Cohort Studies; D005260:Female; D006801:Humans; D050356:Lipid Metabolism / Q000187:drug effects / Q000502:physiology*; D008137:Longitudinal Studies; D008297:Male; D008727:Methotrexate / Q000627:therapeutic use*; D008875:Middle Aged; D012189:Retrospective Studies; D014280:Triglycerides / Q000097:blood; D014409:Tumor Necrosis Factor-alpha / Q000037:antagonists & inhibitors*
chemical_list: D018501:Antirheumatic Agents; D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D014280:Triglycerides; D014409:Tumor Necrosis Factor-alpha; D008727:Methotrexate