title: Screening and identification of disaccharides with insulin mimetic activity against L6 cells.
abstract: Insulin mimetics are considered as prospective anti-diabetic agents, and the disaccharide, neohesperidose, has been found to show insulin mimetic activity against L6 cells. We screened several other disaccharides for their insulin mimetic activity and identified three new insulin mimetic disaccharides.
authors.affiliation: Laboratory of Food Biochemistry, Division of Applied Bioscience, Graduate School of Agriculture, Hokkaido University, Kita-ku, Sapporo, Japan.
authors.forename: Kazuaki
authors.initials: K
authors.lastname: Yamasaki
authors.forename: Ryogo
authors.initials: R
authors.lastname: Hishiki
authors.forename: Eisuke
authors.initials: E
authors.lastname: Kato
authors.forename: Jun
authors.initials: J
authors.lastname: Kawabata
mesh_terms: D000818:Animals; D001692:Biological Transport / Q000187:drug effects; D040761:Biomimetic Materials / Q000737:chemistry* / Q000494:pharmacology; D002460:Cell Line; D003847:Deoxyglucose / Q000378:metabolism; D003920:Diabetes Mellitus / Q000378:metabolism; D004187:Disaccharides / Q000737:chemistry* / Q000494:pharmacology; D006801:Humans; D007004:Hypoglycemic Agents / Q000737:chemistry* / Q000494:pharmacology; D007328:Insulin / Q000494:pharmacology; D051381:Rats
chemical_list: D004187:Disaccharides; D007004:Hypoglycemic Agents; D007328:Insulin; D003847:Deoxyglucose