title: Effects of chlorhexidine oral decontamination on respiratory colonization during mechanical ventilation in intensive care unit patients.
abstract: We conducted a retrospective cohort study to assess respiratory colonization before and after the use of chlorhexidine oral decontamination among a cohort of intensive care unit patients who received mechanical ventilation. We observed a decrease in the prevalence of Enterobacteriaceae and an increase in the incidence of fungal colonization. Chlorhexidine oral decontamination might have a differential effect on respiratory colonization.
authors.affiliation: Department of Internal Medicine, Diakonessenhuis, Utrecht, the Netherlands. d.f.postma@umcutrecht.nl
authors.forename: Douwe F
authors.initials: DF
authors.lastname: Postma
authors.forename: Sanjay U C
authors.initials: SU
authors.lastname: Sankatsing
authors.forename: Steven F T
authors.initials: SF
authors.lastname: Thijsen
authors.forename: Henrik
authors.initials: H
authors.lastname: Endeman
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001419:Bacteria / Q000187:drug effects; D002710:Chlorhexidine / Q000008:administration & dosage*; D003666:Decontamination / Q000379:methods*; D004866:Equipment Contamination; D005260:Female; D006784:Hospitals, Teaching; D006801:Humans; D008297:Male; D008875:Middle Aged; D009067:Mouthwashes / Q000008:administration & dosage*; D009426:Netherlands; D012121:Respiration, Artificial / Q000295:instrumentation*; D012189:Retrospective Studies
chemical_list: D009067:Mouthwashes; D002710:Chlorhexidine