title: Orchestration of metabolism by macrophages.
abstract: Metabolic adaptation is a key component of macrophage plasticity and polarization, instrumental to their function in homeostasis, immunity, and inflammation. Macrophage products also impact metabolism, as illustrated by obesity-associated pathologies. Defining the mechanisms regulating macrophage metabolic activity and orchestration of metabolism by macrophages is crucial to pathology and therapeutic intervention.
authors.affiliation: Singapore Immunology Network, Agency for Science, Technology, and Research, #04-06 Immunos, 8A Biomedical Grove, Singapore, Republic of Singapore. subhra_biswas@immunol.a-star.edu.sg
authors.forename: Subhra K
authors.initials: SK
authors.lastname: Biswas
authors.forename: Alberto
authors.initials: A
authors.lastname: Mantovani
mesh_terms: D000818:Animals; D016764:Cell Polarity; D004194:Disease; D006801:Humans; D008262:Macrophage Activation; D008264:Macrophages / Q000378:metabolism* / Q000473:pathology; D053858:Metabolic Networks and Pathways; D008954:Models, Biological