title: Ultrasensitive colorimetric DNA detection using a combination of rolling circle amplification and nicking endonuclease-assisted nanoparticle amplification (NEANA).
abstract: A combination of rolling circle amplification and nicking endonuclease-assisted nanoparticle amplification (NEANA) is used for the rapid, colorimetric detection of DNA. The integration of rolling circle amplification into the NEANA approach allows for detection of oligonucleotides with arbitrary sequences at ultralow concentrations.
authors.affiliation: Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543.
authors.forename: Wei
authors.initials: W
authors.lastname: Xu
authors.forename: Xiaoji
authors.initials: X
authors.lastname: Xie
authors.forename: Dawei
authors.initials: D
authors.lastname: Li
authors.forename: Zhaoqi
authors.initials: Z
authors.lastname: Yang
authors.forename: Tianhu
authors.initials: T
authors.lastname: Li
authors.forename: Xiaogang
authors.initials: X
authors.lastname: Liu
mesh_terms: D001483:Base Sequence; D003124:Colorimetry / Q000379:methods*; D004247:DNA / Q000032:analysis* / Q000737:chemistry; D004720:Endonucleases / Q000378:metabolism; D004926:Escherichia coli / Q000378:metabolism; D006046:Gold / Q000737:chemistry; D053768:Metal Nanoparticles / Q000737:chemistry; D018625:Microscopy, Atomic Force; D008969:Molecular Sequence Data; D053758:Nanoparticles / Q000737:chemistry*; D021141:Nucleic Acid Amplification Techniques; D009693:Nucleic Acid Hybridization; D009841:Oligonucleotides / Q000737:chemistry; D012689:Sequence Homology, Nucleic Acid
chemical_list: D009841:Oligonucleotides; D006046:Gold; D004247:DNA; D004720:Endonucleases