title: Breast cancer tumor size assessment with mammography, ultrasonography, and magnetic resonance imaging at a community based multidisciplinary breast center.
abstract: Paramount to staging and patient management is accurately measuring the size of invasive breast cancers. We assessed the accuracy of mammography (MG), ultrasonography (US), and magnetic resonance imaging (MRI) at our community-based hospital in which multiple radiologists and imaging  machines are used in the care of our patients. We performed a retrospective analysis of a prospectively maintained database of 277 patients seen at our breast center from 2009 to 2010. We tabulated MG, US, and MRI-reported tumor sizes in 161 women with pathology-proven invasive breast cancer  and compared the preoperative size measurements with final pathologic tumor size. In the 161 patients, 169 lesions were identified. Imaging using all three modalities was available in 47 patients. When compared with final pathology, MRI had a correlation of r = 0.75 to mean tumor size as compared  with US (r = 0.67) and MG (r = 0.76). Mean tumor size was 1.90 cm by MG, 1.87 cm by US, 2.40 cm by MRI, and 2.19 cm by pathology. We were able to achieve an excellent correlation of pathologic tumor size to preoperative imaging. The absolute differences in size between the modalities were  small. MRI, in select patients, added to the assessment of tumor size based on US and MG.
authors.affiliation: Department of Surgery, Saint Agnes Hospital, Baltimore, Maryland, USA.
authors.forename: Sarah Ines
authors.initials: SI
authors.lastname: Ramirez
authors.forename: Max
authors.initials: M
authors.lastname: Scholle
authors.forename: Jennifer
authors.initials: J
authors.lastname: Buckmaster
authors.forename: Robert Hunter
authors.initials: RH
authors.lastname: Paley
authors.forename: Gopal Chandru
authors.initials: GC
authors.lastname: Kowdley
mesh_terms: D000368:Aged; D001943:Breast Neoplasms / Q000175:diagnosis / Q000473:pathology*; D003151:Community Health Centers; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008327:Mammography; D008875:Middle Aged; D012189:Retrospective Studies; D047368:Tumor Burden; D016217:Ultrasonography, Mammary