title: Animal models of eating disorders.
abstract: Feeding is a fundamental process for basic survival and is influenced by genetics and environmental stressors. Recent advances in our understanding of behavioral genetics have provided a profound insight on several components regulating eating patterns. However, our understanding of eating disorders, such as anorexia nervosa, bulimia nervosa, and binge eating, is still poor. The animal model is an essential tool in the investigation of eating behaviors and their pathological forms, yet development of an appropriate animal model for eating disorders still remains challenging due to our limited knowledge and some of the more ambiguous clinical diagnostic measures. Therefore, this review will serve to focus on the basic clinical features of eating disorders and the current advances in animal models of eating disorders.
authors.affiliation: Center for Neurobiology and Behavior, Department of Psychiatry and Pharmacology, The Perelman School of Medicine University of Pennsylvania, 125 S 31st St., TRL Rm 2207, Philadelphia, PA 19104, USA. sangwonk@mail.med.upenn.edu
authors.forename: S F
authors.initials: SF
authors.lastname: Kim
mesh_terms: D000818:Animals; D000856:Anorexia Nervosa / Q000175:diagnosis / Q000503:physiopathology / Q000523:psychology; D056912:Binge-Eating Disorder / Q000175:diagnosis / Q000503:physiopathology / Q000523:psychology; D052018:Bulimia Nervosa / Q000175:diagnosis / Q000503:physiopathology / Q000523:psychology; D004195:Disease Models, Animal; D006801:Humans