title: Earlier detection of bone metastases from pleomorphic liposarcoma in a pediatric patient by FDG PET/CT than planar 99mTc MDP bone scan.
abstract: Bone scintigraphy using (99m)TC MDP (technetium-99m methylene diphosphonate) is a routine procedure for evaluation of osteoblastic metastases; however, its sensitivity compared with FDG PET/CT in a variety of malignancies remains to be established. We report a case of multiple osseous metastases revealed by FDG PET/CT in an 8-year-old girl with pleomorphic liposarcoma. Many of these osseous lesions were not visualized on the MDP planar bone scintigraphy performed 24 hours after PET/CT scan, becoming evident only on repeat bone scan performed 3 months later. The case suggests that FDG PET/CT has higher sensitivity in detecting osteoblastic metastases in pleomorphic liposarcoma.
authors.affiliation: Department of Nuclear Medicine, Beijing Friendship Hospital of Capital Medical University, Beijing, China.
authors.forename: Jigang
authors.initials: J
authors.lastname: Yang
authors.forename: Ion
authors.initials: I
authors.lastname: Codreanu
authors.forename: Sabah
authors.initials: S
authors.lastname: Servaes
authors.forename: Hongming
authors.initials: H
authors.lastname: Zhuang
mesh_terms: D001859:Bone Neoplasms / Q000000981:diagnostic imaging* / Q000556:secondary*; D001842:Bone and Bones / Q000000981:diagnostic imaging; D002648:Child; D055088:Early Detection of Cancer; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008080:Liposarcoma / Q000473:pathology*; D064847:Multimodal Imaging / Q000379:methods*; D049268:Positron-Emission Tomography; D013669:Technetium Tc 99m Medronate; D014057:Tomography, X-Ray Computed; D051598:Whole Body Imaging
chemical_list: D019788:Fluorodeoxyglucose F18; D013669:Technetium Tc 99m Medronate