title: Growth velocity in infancy influences resting energy expenditure in 12-14 year-old obese adolescents.
abstract: OBJECTIVE
  : To determine if rapid growth between 0 and 2 years of life influences body composition and resting energy expenditure (REE) measured at 12-14 years in a population of obese children.
  
  
  METHODS
  REE and body composition were measured in 107 obese children aged 12-14 years in whom weight at birth and 2 years was recorded.
  
  
  RESULTS
  46 obese children had a rapid growth between birth and 2 years (>0.67 SD). Rapid weight gain was positively correlated with weight and height at 12-14 years but not with body mass index (BMI). Fat mass (FM) to fat free mass (FFM) ratio was not significantly different at 12-14 years in children with rapid or normal growth velocity. REE in 12-14 year-old children with rapid growth (1765±222kcal/24h) was significantly higher than children with normal growth velocity (1586±216kcal/24h) (P<0.001). REE adjusted for FFM was similar in the two groups.
  
  
  CONCLUSIONS
  Rapid weight gain between 0 and 2 years of life is associated with higher weight, height, FFM, FM and REE in 12-14 year-old obese children despite identical BMI. These data demonstrate that growth velocity affects later body composition and REE in obese adolescents but relationship between REE and FFM is preserved.
authors.affiliation: Clermont Université, Université d'Auvergne, Unité de Nutrition Humaine, BP 10448, F-63000 Clermont-Ferrand, France. mbatisse@chu-clermontferrand.fr
authors.forename: M
authors.initials: M
authors.lastname: Batisse-Lignier
authors.forename: S
authors.initials: S
authors.lastname: Rousset
authors.forename: A
authors.initials: A
authors.lastname: Labbé
authors.forename: Y
authors.initials: Y
authors.lastname: Boirie
mesh_terms: D000293:Adolescent; D000886:Anthropometry; D001481:Basal Metabolism; D001823:Body Composition; D002153:Calorimetry, Indirect; D002648:Child; D002657:Child Development; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D009765:Obesity / Q000378:metabolism / Q000503:physiopathology*; D015430:Weight Gain / Q000502:physiology