title: Management of elderly patients with breast cancer: updated recommendations of the International Society of Geriatric Oncology (SIOG) and European Society of Breast Cancer Specialists (EUSOMA).
abstract: As the mean age of the global population increases, breast cancer in older individuals will be increasingly encountered in clinical practice. Management decisions should not be based on age alone. Establishing recommendations for management of older individuals with breast cancer is challenging because of very limited level 1 evidence in this heterogeneous population. In 2007, the International Society of Geriatric Oncology (SIOG) created a task force to provide evidence-based recommendations for the management of breast cancer in elderly individuals. In 2010, a multidisciplinary SIOG and European Society of Breast Cancer Specialists (EUSOMA) task force gathered to expand and update the 2007 recommendations. The recommendations were expanded to include geriatric assessment, competing causes of mortality, ductal carcinoma in situ, drug safety and compliance, patient preferences, barriers to treatment, and male breast cancer. Recommendations were updated for screening, primary endocrine therapy, surgery, radiotherapy, neoadjuvant and adjuvant systemic therapy, and metastatic breast cancer.
authors.affiliation: Sandro Pitigliani Medical Oncology Unit, Istituto Toscano Tumori, Hospital of Prato, Prato, Italy. lbiganzoli@usl4.toscana.it
authors.forename: Laura
authors.initials: L
authors.lastname: Biganzoli
authors.forename: Hans
authors.initials: H
authors.lastname: Wildiers
authors.forename: Catherine
authors.initials: C
authors.lastname: Oakman
authors.forename: Lorenza
authors.initials: L
authors.lastname: Marotti
authors.forename: Sibylle
authors.initials: S
authors.lastname: Loibl
authors.forename: Ian
authors.initials: I
authors.lastname: Kunkler
authors.forename: Malcolm
authors.initials: M
authors.lastname: Reed
authors.forename: Stefano
authors.initials: S
authors.lastname: Ciatto
authors.forename: Adri C
authors.initials: AC
authors.lastname: Voogd
authors.forename: Etienne
authors.initials: E
authors.lastname: Brain
authors.forename: Bruno
authors.initials: B
authors.lastname: Cutuli
authors.forename: Catherine
authors.initials: C
authors.lastname: Terret
authors.forename: Margot
authors.initials: M
authors.lastname: Gosney
authors.forename: Matti
authors.initials: M
authors.lastname: Aapro
authors.forename: Riccardo
authors.initials: R
authors.lastname: Audisio
mesh_terms: D000368:Aged; D001943:Breast Neoplasms / Q000453:epidemiology* / Q000473:pathology / Q000628:therapy*; D018567:Breast Neoplasms, Male / Q000453:epidemiology / Q000473:pathology / Q000628:therapy; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000453:epidemiology* / Q000473:pathology / Q000628:therapy*; D003131:Combined Modality Therapy; D003657:Decision Making; D005060:Europe / Q000453:epidemiology; D005260:Female; D015577:Geriatric Assessment; D006801:Humans; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D009367:Neoplasm Staging; D017410:Practice Guidelines as Topic; D012955:Societies, Medical