title: Biological correlates and predictors of insulin resistance among early adolescents.
abstract: Abnormal glucose metabolism is associated with obesity, insulin resistance (IR), and Type 2 diabetes mellitus. The purposes of this study were to describe anthropometric and laboratory markers of adolescents, examine correlates of IR, and test ability of anthropometric and laboratory markers to predict risk of exhibiting IR. A total of 150 early adolescents participated. Participants with obesity had increased IR, high-sensitivity C-reactive protein, triglycerides, and blood pressure. Waist circumference and triglycerides were predictive of IR. Multiple risk factors compound and lead to long-term health consequences among youth. Nurses can evaluate these factors to identify IR.
authors.affiliation: Washington State University, College of Pharmacy, Spokane, WA, USA. bindler@wsu.edu
authors.forename: Ross J
authors.initials: RJ
authors.lastname: Bindler
authors.forename: Ruth C
authors.initials: RC
authors.lastname: Bindler
authors.forename: Kenneth B
authors.initials: KB
authors.lastname: Daratha
mesh_terms: D000293:Adolescent; D002097:C-Reactive Protein / Q000032:analysis; D008076:Cholesterol, HDL / Q000097:blood; D005260:Female; D006801:Humans; D007333:Insulin Resistance / Q000502:physiology; D008297:Male; D009765:Obesity / Q000517:prevention & control; D015995:Prevalence; D012307:Risk Factors; D014280:Triglycerides / Q000097:blood; D055105:Waist Circumference
chemical_list: D008076:Cholesterol, HDL; D014280:Triglycerides; D002097:C-Reactive Protein