title: Adverse effect of low-dose amiodarone mimicking pulmonary malignancy.
abstract: A 74-year-old woman presented with a one-week history of persistent cough. A chest x-ray and computed tomography images revealed features mimicking lung cancer, which included a large solitary consolidation and hilar lymphadenopathy. She had received low-dose amiodarone (200 mg/day) for treatment of atrial fibrillation for more than 2.5 years. The tumour-like abnormalities did not disappear until the discontinuation of amiodarone therapy. The finding of low-dose amiodarone causing tumour-like abnormalities on a chest x-ray is unique. Once amiodarone-induced tumour-like changes are diagnosed, therapeutic options are limited. In most cases, the tumour-like changes are reversible, if diagnosed early. An unusual case involving amiodarone-induced pulmonary abnormalities is reported, followed by a review of the relevant literature.
authors.affiliation: Department of Medicine;
authors.forename: Hsiao-Ching
authors.initials: HC
authors.lastname: Cheng
authors.forename: Jao-Hsien
authors.initials: JH
authors.lastname: Wang
authors.forename: Ming-Long
authors.initials: ML
authors.lastname: Wang
authors.forename: Ming-Tse
authors.initials: MT
authors.lastname: Sung
authors.forename: Shoa-Lin
authors.initials: SL
authors.lastname: Lin
authors.forename: Tahir
authors.initials: T
authors.lastname: Tak