title: Glucocorticoid-dependent hypoadrenocorticism with thrombocytopenia and neutropenia mimicking sepsis in a Labrador retriever dog.
abstract: Glucocorticoid-deficient hypoadrenocorticism (GDH) with immune-mediated-neutropenia (IMN) and -thrombocytopenia (IMT) were diagnosed in a 3-year-old Labrador retriever dog. Glucocorticoid-deficient hypoadrenocorticism is rare and diagnostically challenging as clinical signs and laboratory abnormalities are often nonspecific. Immune-mediated cytopenias and other autoimmune disorders, as part of an autoimmune polyglandular syndrome have been reported with hypoadrenocorticism in humans. This is the first reported case of hypoadrenocorticism and bicytopenia in a dog.
authors.affiliation: Department of Small Animal Clinical Sciences, University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4. liz.snead@usask.ca
authors.forename: Elisabeth
authors.initials: E
authors.lastname: Snead
authors.forename: Cheryl
authors.initials: C
authors.lastname: Vargo
authors.forename: Sherry
authors.initials: S
authors.lastname: Myers
mesh_terms: D000309:Adrenal Insufficiency / Q000175:diagnosis / Q000662:veterinary*; D000818:Animals; D003937:Diagnosis, Differential; D004283:Dog Diseases / Q000175:diagnosis*; D004285:Dogs; D005938:Glucocorticoids / Q000172:deficiency*; D008297:Male; D009503:Neutropenia / Q000175:diagnosis / Q000662:veterinary*; D018805:Sepsis / Q000175:diagnosis / Q000662:veterinary; D013921:Thrombocytopenia / Q000175:diagnosis / Q000662:veterinary*
chemical_list: D005938:Glucocorticoids