title: An outbreak of post-partum breast abscesses in Mumbai, India caused by ST22-MRSA-IV: genetic characteristics and epidemiological implications.
abstract: A cluster of methicillin-resistant Staphylococcus aureus (MRSA) breast abscesses in women who had given birth at a hospital in Mumbai, India was investigated retrospectively. Nineteen of 20 cases were caused by a single clone: pvl-positive, spa type 648 (Ridom t852), ccrB:dru subtype 3:0, ST22-MRSA-IV. Despite the presence of pvl and SCCmec type IV, which are common genetic markers in community-associated MRSA, this outbreak was caused by a healthcare-associated, community-onset MRSA that was common in the hospital environment. Thus, infection control practices may have an important role in limiting the spread of this virulent clone.
authors.affiliation: Department of Medicine Unit I and Infectious Diseases, Christian Medical College, Vellore, India.
authors.forename: A
authors.initials: A
authors.lastname: Manoharan
authors.forename: L
authors.initials: L
authors.lastname: Zhang
authors.forename: A
authors.initials: A
authors.lastname: Poojary
authors.forename: L
authors.initials: L
authors.lastname: Bhandarkar
authors.forename: G
authors.initials: G
authors.lastname: Koppikar
authors.forename: D A
authors.initials: DA
authors.lastname: Robinson
mesh_terms: D000038:Abscess / Q000453:epidemiology* / Q000382:microbiology; D016000:Cluster Analysis; D004196:Disease Outbreaks; D005260:Female; D006801:Humans; D007194:India / Q000453:epidemiology; D008413:Mastitis / Q000453:epidemiology* / Q000382:microbiology; D055624:Methicillin-Resistant Staphylococcus aureus / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification*; D058889:Molecular Typing; D049590:Postpartum Period; D011247:Pregnancy; D012189:Retrospective Studies; D013203:Staphylococcal Infections / Q000453:epidemiology* / Q000382:microbiology; D037521:Virulence Factors / Q000235:genetics
chemical_list: D037521:Virulence Factors