title: Use of spectral-domain optical coherence tomography to differentiate acquired retinoschisis from retinal detachment in difficult cases.
abstract: OBJECTIVE
  This study presents a series of 10 patients who posed a diagnostic challenge regarding the diagnosis of acquired retinoschisis (RS) or retinal detachment (RD), where spectral-domain optical coherence tomography (OCT) with the Spectralis HRA and OCT device (Heidelberg Engineering, Heidelberg, Germany) was able to help make a correct diagnosis.
  
  
  METHODS
  Ten patients (five with acquired RS and five with RD) were referred to a vitreoretinal clinic at Moorfields Eye Hospital for definitive diagnosis and further management. All patients underwent scans with the Spectralis HRA and OCT device.
  
  
  RESULTS
  The Spectralis HRA and OCT was able to make a clear diagnosis of RS or RD in all patients. Of the five patients with RS confirmed on OCT, two were referred with RD, and of the five patients with RD, four were referred with RS. New OCT features of RS include the double schisis cavity phenomenon, intraretinal pillars through the schisis cavity, and irregularity of the inner surface of the attached outer leaf.
  
  
  CONCLUSIONS
  Spectral-domain OCT is a useful tool in distinguishing RS from RD, eliminating previous diagnostic uncertainty. The Spectralis HRA and OCT device has the added advantages of being able to reliably image anterior retinal pathology and produce high-definition images.
authors.affiliation: Moorfields Eye Hospital, London, United Kingdom.
authors.forename: Jonathan
authors.initials: J
authors.lastname: Yeoh
authors.forename: Waheeda
authors.initials: W
authors.lastname: Rahman
authors.forename: Fred K
authors.initials: FK
authors.lastname: Chen
authors.forename: Lyndon
authors.initials: L
authors.lastname: da Cruz
mesh_terms: D000328:Adult; D000369:Aged, 80 and over; D003937:Diagnosis, Differential; D003941:Diagnostic Techniques, Ophthalmological; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012160:Retina / Q000473:pathology*; D012163:Retinal Detachment / Q000175:diagnosis*; D041441:Retinoschisis / Q000175:diagnosis*; D041623:Tomography, Optical Coherence