title: Primary orbital pleomorphic liposarcoma:  an aggressive course.
abstract: An aggressively poor course of primary orbital pleomorphic liposarcoma is presented. A 59-year-old man had suffered from multiple local recurrences and died 1 year after diagnosis of orbital pleomorphic liposarcoma. The tumor invaded into the brain only 10 months after exenteration. The patient had a history of partial tumor resection via anterior orbitotomy before total exenteration. It was assume that such an unusual poor course might be due to histologic findings, which revealed a high-grade pleomorphic liposarcoma with a high mitotic count (25/10 high-power field) or previous-done anterior orbitotomy, which was able to seed the tumor cells.
authors.affiliation: Department of Ophthalmology, The Institute of Vision Research, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: Sun Young
authors.initials: SY
authors.lastname: Jang
authors.forename: Su Yan
authors.initials: SY
authors.lastname: Zhao
authors.forename: Jin Hyung
authors.initials: JH
authors.lastname: Kim
authors.forename: Min Ju
authors.initials: MJ
authors.lastname: Kim
authors.forename: Jin Sook
authors.initials: JS
authors.lastname: Yoon
authors.forename: Sang Yeul
authors.initials: SY
authors.lastname: Lee
mesh_terms: D005094:Exophthalmos; D017809:Fatal Outcome; D006801:Humans; D008080:Liposarcoma / Q000000981:diagnostic imaging / Q000473:pathology* / Q000532:radiotherapy; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009364:Neoplasm Recurrence, Local / Q000473:pathology*; D009918:Orbital Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000532:radiotherapy; D014057:Tomography, X-Ray Computed