title: Coherence and other autistic spectrum traits and eating disorders: building from mechanism to treatment. The Birgit Olsson lecture.
abstract: OBJECTIVE
  To revisit Gillberg's hypothesis proposed in 1992, which was that anorexia nervosa should be considered within the spectrum of autistic disorders.
  
  
  METHODS
  A search was made of the literature relating to the behavioural traits, and cognitive, emotional and neuroanatomical intermediate phenotypes that are shared between autistic spectrum disorders (ASD) and anorexia nervosa.
  
  
  RESULTS
  People with eating disorders in the acute phase (less so after recovery) share some behavioural traits (social impairment and restricted and repetitive behaviours) and intermediate phenotypes (weak central coherence, and impaired set shifting and theory of mind) with people in the autistic spectrum.
  
  
  CONCLUSIONS
  Behavioural and intermediate neuropsychological traits are shared between eating disorders and ASD. In part, these are familial but also they are accentuated by the illness state and may be secondary to starvation. These traits have implications for prognosis and treatment.
authors.affiliation: Kings College London Institute of Psychiatry, Department Academic Psychiatry, Denmark Hill, London, UK. Janet.Treasure@kcl.ac.uk
authors.forename: Janet
authors.initials: J
authors.lastname: Treasure
mesh_terms: D000856:Anorexia Nervosa / Q000145:classification / Q000235:genetics / Q000523:psychology* / Q000628:therapy; D001321:Autistic Disorder / Q000235:genetics / Q000523:psychology* / Q000628:therapy; D015897:Comorbidity; D004644:Emotions; D006801:Humans; D010641:Phenotype