title: [Proven and expected benefits of intravenous lidocaine administered during the perioperative period].
abstract: Local anesthetics which inhibit sodium channels are used for neural blockade during infiltration and locoregional anesthesia. Furthermore lidocaine given intravenously acts on other cellular systems and produces multiple properties, some of which are beneficial during the perioperative period. Indeed, intravenous lidocaine is analgesic, antihyperalgesic, antiinflammatory, and improves the recovery of bowel function after abdominal surgery. As a consequence, lidocaine has been added to postoperative analgesic strategies. This article reviews clinically relevant properties of intravenous lidocaine. Its future perspectives for the prevention of chronicisation of postoperative pain, facilitation of postoperative fast track programs, and prevention of tumoral recurrence are also discussed.
authors.affiliation: Service d'Anesthésie Réanimation, CHU de Liège, Université de Liège, Belgique.
authors.forename: V
authors.initials: V
authors.lastname: Giudice
authors.forename: S
authors.initials: S
authors.lastname: Lauwick
authors.forename: A
authors.initials: A
authors.lastname: Kaba
authors.forename: J
authors.initials: J
authors.lastname: Joris
mesh_terms: D000779:Anesthetics, Local / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D006801:Humans; D007262:Infusions, Intravenous; D008012:Lidocaine / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D010149:Postoperative Pain / Q000517:prevention & control*; D019990:Perioperative Care; D016896:Treatment Outcome
chemical_list: D000779:Anesthetics, Local; D008012:Lidocaine