title: Malignant change in a massive pleomorphic adenoma resembling the presentation of advanced inflammatory breast cancer.
abstract: Massive tumours of the parotid are uncommon as due to their site, they are usually removed at an earlier stage. We present a bizarre case of a carcinoma ex-pleomorphic adenoma which mimicked an advanced breast cancer, complete with a 'nipple-like' extension and peau d'orange changes in the overlying skin as a result of a dense dermal inflammatory response. A procedure akin to a mastectomy with facial nerve preservation was carried out for removal. To our knowledge, peau d'orange has not been reported before in parotid tumours.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Queen Alexandra Hospital, Portsmouth PO6 3LY, UK.
authors.forename: Leonie
authors.initials: L
authors.lastname: Seager
authors.forename: Serryth
authors.initials: S
authors.lastname: Colbert
authors.forename: Anne V
authors.initials: AV
authors.lastname: Spedding
authors.forename: Peter A
authors.initials: PA
authors.lastname: Brennan
mesh_terms: D008949:Adenoma, Pleomorphic / Q000473:pathology*; D000368:Aged; D002277:Carcinoma / Q000473:pathology*; D002471:Cell Transformation, Neoplastic / Q000473:pathology*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D058922:Inflammatory Breast Neoplasms / Q000175:diagnosis; D010307:Parotid Neoplasms / Q000473:pathology*