title: Palladium-catalyzed cascade process to construct 1,2,5-trisubstituted pyrroles.
abstract: A novel palladium-catalyzed cascade allylic amination/intramolecular hydroamination/isomerization process of protected enynol 1 and primary amine 2 has been explored, which constructs the important 1,2,5-trisubstituted pyrroles. This transformation offers an alternative synthetic methodology capable of generating substituted pyrroles in a straightforward way.
authors.affiliation: State Key Laboratory of Applied Organic Chemistry and College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, PR China.
authors.forename: Yong-Qiang
authors.initials: YQ
authors.lastname: Zhang
authors.forename: Dao-Yong
authors.initials: DY
authors.lastname: Zhu
authors.forename: Bao-Sheng
authors.initials: BS
authors.lastname: Li
authors.forename: Yong-Qiang
authors.initials: YQ
authors.lastname: Tu
authors.forename: Ji-Xin
authors.initials: JX
authors.lastname: Liu
authors.forename: Yong
authors.initials: Y
authors.lastname: Lu
authors.forename: Shao-Hua
authors.initials: SH
authors.lastname: Wang