title: First case report of bloodstream infection due to a Candida species closely related to the novel species Candida pseudorugosa.
abstract: Candida pseudorugosa is a novel species closely related to Candida rugosa for which only one case has been reported. We report the first case of a bloodstream infection in humans caused by a Candida sp. closely related to C. pseudorugosa. We contribute evidence to show this organism as a potential human pathogen that may be misidentified by conventional methods, also pointing out its lower sensitivity to azoles and other antifungal agents.
authors.affiliation: Departamento Micología, Instituto Nacional de Enfermedades Infecciosas Dr. Carlos G. Malbrán, Ciudad Autónoma de Buenos Aires, Argentina. ctaverna@anlis.gov.ar
authors.forename: Constanza Giselle
authors.initials: CG
authors.lastname: Taverna
authors.forename: Susana
authors.initials: S
authors.lastname: Córdoba
authors.forename: Guillermina
authors.initials: G
authors.lastname: Isla
authors.forename: Norma
authors.initials: N
authors.lastname: Fernández
authors.forename: Susana
authors.initials: S
authors.lastname: García
authors.forename: Mariana
authors.initials: M
authors.lastname: Mazza
authors.forename: Omar Alejandro
authors.initials: OA
authors.lastname: Murisengo
authors.forename: Walter
authors.initials: W
authors.lastname: Vivot
authors.forename: Wanda
authors.initials: W
authors.lastname: Szusz
authors.forename: Graciela
authors.initials: G
authors.lastname: Davel
authors.forename: Iris Nora
authors.initials: IN
authors.lastname: Tiraboschi
authors.forename: María Eugenia
authors.initials: ME
authors.lastname: Bosco-Borgeat
mesh_terms: D000935:Antifungal Agents / Q000494:pharmacology; D001393:Azoles / Q000494:pharmacology; D002175:Candida / Q000145:classification / Q000187:drug effects / Q000235:genetics / Q000302:isolation & purification*; D058387:Candidemia / Q000175:diagnosis* / Q000382:microbiology; D016000:Cluster Analysis; D004271:DNA, Fungal / Q000737:chemistry / Q000235:genetics; D021903:DNA, Ribosomal Spacer / Q000737:chemistry / Q000235:genetics; D005260:Female; D006801:Humans; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D008969:Molecular Sequence Data; D010802:Phylogeny; D017422:Sequence Analysis, DNA
chemical_list: D000935:Antifungal Agents; D001393:Azoles; D004271:DNA, Fungal; D021903:DNA, Ribosomal Spacer