title: Influence of visceral and subcutaneous fat in bone mineral density of obese adolescents.
abstract: OBJECTIVE
  To verify the influence of visceral and subcutaneous fat, as well adipokines in bone mineral density (BMD) in obese adolescents.
  
  
  METHODS
  The study involved 125 postpubertal obese adolescents (45 boys and 80 girls). Anthropometric measurements, body composition, visceral and subcutaneous fat, and BMD were determined. Leptin, adiponectin, and insulin levels also analyzed.
  
  
  RESULTS
  Data demonstrated a negative relationship between BMD with insulin resistance, visceral fat and leptin concentration; and bone mineral content with visceral/subcutaneous ratio. Positive association between BMD and subcutaneous fat was observed.
  
  
  CONCLUSIONS
  Visceral fat and insulin resistance, as well as visceral/subcutaneous ratio and leptin concentration, were negative predictors of BMD in boys and girls, respectively. However, subcutaneous fat had a protective influence in BMD only in boys.
authors.affiliation: Graduate Studies Program in Nutrition, Universidade Federal de São Paulo, Brazil. raquelmunhoz@hotmail.com
authors.forename: Raquel M S
authors.initials: RM
authors.lastname: Campos
authors.forename: Marise
authors.initials: M
authors.lastname: Lazaretti-Castro
authors.forename: Marco Túlio de
authors.initials: MT
authors.lastname: Mello
authors.forename: Lian
authors.initials: L
authors.lastname: Tock
authors.forename: Patricia L
authors.initials: PL
authors.lastname: Silva
authors.forename: Flávia C
authors.initials: FC
authors.lastname: Corgosinho
authors.forename: June
authors.initials: J
authors.lastname: Carnier
authors.forename: Aline de
authors.initials: Ad
authors.lastname: Piano
authors.forename: Priscila L
authors.initials: PL
authors.lastname: Sanches
authors.forename: Deborah C L
authors.initials: DC
authors.lastname: Masquio
authors.forename: Sergio
authors.initials: S
authors.lastname: Tufik
authors.forename: Ana R
authors.initials: AR
authors.lastname: Dâmaso
mesh_terms: D054392:Adipokines / Q000097:blood*; D000293:Adolescent; D015519:Bone Density / Q000502:physiology*; D005260:Female; D006801:Humans; D050152:Intra-Abdominal Fat / Q000000981:diagnostic imaging*; D020738:Leptin / Q000097:blood; D016014:Linear Models; D008297:Male; D009765:Obesity / Q000000981:diagnostic imaging / Q000503:physiopathology*; D012737:Sex Factors; D018709:Statistics, Nonparametric; D050151:Subcutaneous Fat / Q000000981:diagnostic imaging*; D014463:Ultrasonography
chemical_list: D054392:Adipokines; D020738:Leptin