title: R loops: lassoing DNA methylation at CpGi.
abstract: In this issue of Molecular Cell, Ginno et al. (2012) describe unusual sequence features at promoter CpG islands that can lead to formation of persistent RNA-DNA hybrids (R loops), which are proposed to prevent genomic DNA methylation.
authors.affiliation: Department of Radiation Oncology and the Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA 30307, USA. pvertin@emory.edu
authors.forename: Paula M
authors.initials: PM
authors.lastname: Vertino
authors.forename: Paul A
authors.initials: PA
authors.lastname: Wade