title: Histopathologic analysis of bladder in patient with cloacal exstrophy.
abstract: We report the case of a newborn infant with cloacal exstrophy. On the 16th day after birth, complete primary exstrophy repair was performed. The bladder tissue obtained during surgery contained collagen tissue and a little smooth muscle, as well as a few neuron cells and kit-positive interstitial cells in the submucosal layer. This is the first report of a histopathologic analysis of the bladder tissue in cloacal exstrophy. We also discuss the influence of the pathologic changes on bladder dysfunction.
authors.affiliation: Department of Nephro-urology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.
authors.forename: Yoshinobu
authors.initials: Y
authors.lastname: Moritoki
authors.forename: Yoshiyuki
authors.initials: Y
authors.lastname: Kojima
authors.forename: Kentaro
authors.initials: K
authors.lastname: Mizuno
authors.forename: Hideyuki
authors.initials: H
authors.lastname: Kamisawa
authors.forename: Kenjiro
authors.initials: K
authors.lastname: Kohri
authors.forename: Yutaro
authors.initials: Y
authors.lastname: Hayashi
mesh_terms: D000015:Abnormalities, Multiple; D001746:Bladder Exstrophy / Q000378:metabolism / Q000473:pathology* / Q000503:physiopathology / Q000601:surgery; D002988:Cloaca / Q000002:abnormalities*; D006801:Humans; D007150:Immunohistochemistry; D007231:Infant, Newborn; D001743:Urinary Bladder / Q000473:pathology*; D001750:Urinary Bladder, Neurogenic / Q000473:pathology / Q000503:physiopathology; D014563:Urodynamics