title: A case of sinobronchial syndrome complicated with myeloperoxidase antineutrophil cytoplasmic antibody associated vasculitis: review of the literature.
abstract: We report a case of long-standing sinobronchial syndrome complicated by microscopic polyangiitis (MPA) during the clinical course. The patient showed a mild elevation of myeloperoxidase antineutrophil cytoplasmic antibody (MPO-ANCA) 17 months prior to the diagnosis of MPA. Subsequently, her MPO-ANCA level gradually became more elevated, and finally her MPO-ANCA level peaked when purpura appeared. Histologic examination of the skin biopsy was consistent with leukocytoclastic vasculitis. Based on the pathological and clinical findings, a diagnosis of MPA was made. Corticosteroid therapy finally led to a remission of MPA with normalized MPO-ANCA titers.
authors.affiliation: Department of Pulmonary Medicine, National Hospital Organization Matsue Medical Center, Japan. toruyan@matsue.hosp.go.jp
authors.forename: Toru
authors.initials: T
authors.lastname: Kadowaki
authors.forename: Shuichi
authors.initials: S
authors.lastname: Yano
authors.forename: Ichiro
authors.initials: I
authors.lastname: Yamadori
authors.forename: Kunio
authors.initials: K
authors.lastname: Araki
authors.forename: Masahiro
authors.initials: M
authors.lastname: Kimura
authors.forename: Kiryo
authors.initials: K
authors.lastname: Wakabayashi
authors.forename: Kanako
authors.initials: K
authors.lastname: Kobayashi
authors.forename: Shigenori
authors.initials: S
authors.lastname: Ishikawa
authors.forename: Toshikazu
authors.initials: T
authors.lastname: Ikeda
mesh_terms: D000368:Aged; D056648:Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis / Q000209:etiology* / Q000276:immunology / Q000473:pathology; D019268:Antibodies, Antineutrophil Cytoplasmic / Q000097:blood; D001987:Bronchiectasis / Q000150:complications* / Q000276:immunology; D005260:Female; D006801:Humans; D009195:Peroxidase / Q000276:immunology; D012852:Sinusitis / Q000150:complications / Q000276:immunology; D013577:Syndrome
chemical_list: D019268:Antibodies, Antineutrophil Cytoplasmic; D009195:Peroxidase