title: The Oxford medial unicompartmental knee replacement: survival and the affect of age and gender.
abstract: OBJECTIVE
  To determine the survival and functional outcome for the phase 3 Oxford unicompartmental knee replacement (UKR) performed at a single independent centre and to assess whether age and gender affect survival.
  
  
  METHODS
  Between 2000 and 2008, 459 consecutive Oxford UKRs were implanted in 392 patients using a minimally invasive technique.
  
  
  RESULTS
  Mean age of patients was 63.0 years and 53% were female. Mean follow-up was 4.4 years (range 0.5-11.2 years). No patient was lost to follow-up and 411 (90%) knees had a minimum follow-up of 2 years. Twenty knees (4.4%) have undergone revision to total knee replacement at a mean time of 3.2 years. Aseptic component loosening (n=11) accounted for most failures. Cumulative survival was 94.4% at 5 years (95% confidence interval 90.9-97.0) and 93.0% at 8 years (95% confidence interval 84.8-96.2). The median postoperative Oxford knee score was 31.2% (interquartile range 12.2%-52.1%) at latest follow-up. Age and gender had no statistically significant affect on UKR survival.
  
  
  CONCLUSIONS
  This large independent series demonstrates good medium-term survival and functional outcome can be achieved with the phase 3 Oxford UKR in appropriately selected patients. Age and gender should not be considered contraindications for performing Oxford UKR.
authors.affiliation: Royal Orthopaedic Hospital, Northfield, Birmingham, B31 2AP United Kingdom. gsm@doctors.org.uk
authors.forename: Gulraj
authors.initials: G
authors.lastname: Matharu
authors.forename: Curtis
authors.initials: C
authors.lastname: Robb
authors.forename: Khalid
authors.initials: K
authors.lastname: Baloch
authors.forename: Paul
authors.initials: P
authors.lastname: Pynsent
mesh_terms: D000367:Age Factors; D019645:Arthroplasty, Replacement, Knee; D015331:Cohort Studies; D005260:Female; D006801:Humans; D007720:Knee Prosthesis; D008297:Male; D020370:Osteoarthritis, Knee / Q000473:pathology / Q000503:physiopathology / Q000601:surgery*; D018579:Patient Selection; D011474:Prosthesis Design; D011475:Prosthesis Failure; D016059:Range of Motion, Articular; D020127:Recovery of Function; D012307:Risk Factors; D012737:Sex Factors; D016896:Treatment Outcome