title: Duodenal GIST metastasized to skull and orbit managed by surgery: a case report.
abstract: We report a 26-year-old man with 6 years, history of duodenal gastrointestinal stromal tumor (GIST) with liver, peritoneum and lung metastases. He presented with left eye ptosis, diplopia, left facial numbness and a left temporal fossa mass that was confirmed to be GIST with left skull and left orbit metastases. Craniectomy with cranioplasty, tumor excision and decompression were performed. There was an improvement of his visual symptoms and facial numbness. To our knowledge, this is one of the few reports of surgical management of GIST, metastasized to skull and orbit, with good symptomatic relief.
authors.affiliation: Division of Neurosurgery, Department of Surgery, The University of Hong Kong, Hong Kong. llfrandom@gmail.com
authors.forename: Lai-Fung
authors.initials: LF
authors.lastname: Li
authors.forename: Yat-Hang
authors.initials: YH
authors.lastname: Tse
authors.forename: Siu-Lun
authors.initials: SL
authors.lastname: Ho
authors.forename: Kin-Wing
authors.initials: KW
authors.lastname: Yan
authors.forename: Wai-Man
authors.initials: WM
authors.lastname: Lui
mesh_terms: D000328:Adult; D056424:Decompressive Craniectomy; D004379:Duodenal Neoplasms / Q000473:pathology*; D046152:Gastrointestinal Stromal Tumors / Q000175:diagnosis / Q000556:secondary / Q000601:surgery*; D006801:Humans; D008297:Male; D009918:Orbital Neoplasms / Q000175:diagnosis / Q000556:secondary / Q000601:surgery; D012888:Skull Neoplasms / Q000175:diagnosis / Q000556:secondary / Q000601:surgery*