title: Localized scleroderma: assessment of the therapeutic response to phototherapy.
abstract: BACKGROUND
  Scleroderma is a chronic autoimmune disease characterized by progressive connective tissue sclerosis and microcirculatory changes. Localized scleroderma is considered a limited disease. However, in some cases atrophic and deforming lesions may be observed that hinder the normal development. Literature reports indicate phototherapy as a therapeutic modality with favorable response in cutaneous forms of scleroderma.
  
  
  OBJECTIVE
  This study had the purpose of assessing the phototherapy treatment for localized scleroderma.
  
  
  METHODS
  Patients with localized scleroderma were selected for phototherapy treatment. They were classified according to the type of localized scleroderma and evolutive stage of the lesions. Clinical examination and skin ultrasound were used to demonstrate the results thus obtained.
  
  
  RESULTS
  Some clinical improvement was observed after an average of 10 phototherapeutic sessions. All skin lesions were softer at clinical palpation with scores reduction upon pre and post treatment comparison. The ultrasound showed that most of the assessed lesions presented a decrease in dermal thickness, and only five maintained their previous measure. Treatment response was similar regardless of the type of phototherapeutic treatment employed.
  
  
  CONCLUSIONS
  The proposed treatment was effective for all lesions, regardless of the phototherapeutic modality employed. The improvement was observed in all treated skin lesions and confirmed by clinical evaluation and skin ultrasound.
authors.affiliation: Irmandade da Santa Casa de Misericórdia de São Paulo, Brasil.
authors.forename: Roberta
authors.initials: R
authors.lastname: Buense
authors.forename: Ida Alzira Gomes
authors.initials: IA
authors.lastname: Duarte
authors.forename: Marcio
authors.initials: M
authors.lastname: Bouer
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D011701:PUVA Therapy; D010789:Phototherapy; D012594:Scleroderma, Localized / Q000473:pathology / Q000628:therapy*; D012867:Skin / Q000000981:diagnostic imaging* / Q000293:injuries; D016896:Treatment Outcome; D014463:Ultrasonography; D055815:Young Adult