title: The regioselective switch for amino-NHC mediated C-H activation of benzimidazole via Ni-Al synergistic catalysis.
abstract: We have disclosed a new mode of a chemically regioselective switch for C-H bond functionalization of benzimidazole derivatives via a cooperative effect invoked by Ni-Al bimetallic catalysis to create a steric requirement for obtaining the linear product of styrene insertion. Yet, excluding the AlMe(3) cocatalyst switches the reaction toward branch selectivity.
authors.affiliation: Institute of Chemistry, Academia Sinica, Nangang, Taipei, Taiwan, Republic of China.
authors.forename: Wei-Chun
authors.initials: WC
authors.lastname: Shih
authors.forename: Wen-Ching
authors.initials: WC
authors.lastname: Chen
authors.forename: Ying-Chieh
authors.initials: YC
authors.lastname: Lai
authors.forename: Ming-Shiuan
authors.initials: MS
authors.lastname: Yu
authors.forename: Jhao-Jhe
authors.initials: JJ
authors.lastname: Ho
authors.forename: Glenn P A
authors.initials: GP
authors.lastname: Yap
authors.forename: Tiow-Gan
authors.initials: TG
authors.lastname: Ong