title: [Immunohistochemical markers in the diagnosis of pigmented conjunctival lesions].
abstract: OBJECTIVE
  The aim of this study was to assess the importance of immunohistochemical markers in the diagnosis of pigmented conjunctival lesions. Due to the difficulty of making an exact clinical diagnosis, the suspicion of malignancy requires the removal of the lesion and performing a histopathology study in which immunohistochemical markers may help to determine the nature of the lesion.
  A case is presented of a 25 year-old woman with a pigmented lesion in the caruncle. It appeared recently and was growing fast with increasing pigmentation. Due to a suspicion of malignancy, the total lesion was removed. The microscopic study revealed cellular alterations which suggested malignancy. However, after carrying out immunohistochemical markers the diagnosis was conjunctival compound nevus.
authors.affiliation: Hospital Clínico San Cecilio, Granada, España. rbellido78@hotmail.com
authors.forename: R M
authors.initials: RM
authors.lastname: Bellido Muñoz
authors.forename: I
authors.initials: I
authors.lastname: Domínguez Hidalgo
authors.forename: J L
authors.initials: JL
authors.lastname: García Serrano
authors.forename: C
authors.initials: C
authors.lastname: López Peña
mesh_terms: D015703:Antigens, CD / Q000032:analysis; D015214:Antigens, Differentiation, Myelomonocytic / Q000032:analysis; D014408:Biomarkers, Tumor; D003230:Conjunctival Neoplasms / Q000737:chemistry / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D058965:MART-1 Antigen / Q000032:analysis; D008545:Melanoma / Q000175:diagnosis; D058950:Melanoma-Specific Antigens / Q000032:analysis; D009508:Nevus, Pigmented / Q000737:chemistry / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D055815:Young Adult; D058951:gp100 Melanoma Antigen; D000097382:CD68 Molecule
chemical_list: D015703:Antigens, CD; D015214:Antigens, Differentiation, Myelomonocytic; D014408:Biomarkers, Tumor; D058965:MART-1 Antigen; D058950:Melanoma-Specific Antigens; D058951:gp100 Melanoma Antigen; C067980:CD68 antigen, human; D000097382:CD68 Molecule; C548637:PMEL protein, human