title: An unusual sarcomatous retroperitoneal metastasis. A rare case report with a brief literature review.
abstract: Retroperitoneal sarcomas are rare tumors associated with a high rate of recurrence and very bad prognosis. Their only efficient treatment is a negative- margin surgical resection that is extremely difficult to achieve. Retroperitoneal metastases from extremity sarcomas are considered unusual. In literature, such a metastatic pattern is described extremely rarely. In this paper we report a case of a very aggressive extremity chondrosarcoma, associated with local recurrence, multiple distant metastases, that finally led to a retroperitoneal metastasis. The recurrence and progression of the sarcoma in this localization were impressive, with a fast overcome of therapeutic options. Chemo- and radiotherapy have not proved to be efficacious in this context and they could have had a role in the deterioration of patient state of health. New tumor markers for the detection and follow-up of these tumors should be considered.
authors.affiliation: Clinic of Surgery I, Bucharest Oncology Institute "Al. Trestioreanu", University of Medicine and Pharmacy "Carol Davila", Bucharest, Romania. angelalazar.2008@yahoo.com
authors.forename: A M
authors.initials: AM
authors.lastname: Lazar
authors.forename: N D
authors.initials: ND
authors.lastname: Straja
authors.forename: E
authors.initials: E
authors.lastname: Brătucu
mesh_terms: D000293:Adolescent; D000671:Amputation, Surgical; D002813:Chondrosarcoma / Q000188:drug therapy / Q000532:radiotherapy / Q000556:secondary* / Q000601:surgery; D005266:Femoral Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery; D006801:Humans; D008297:Male; D009361:Neoplasm Invasiveness; D009364:Neoplasm Recurrence, Local / Q000188:drug therapy / Q000532:radiotherapy / Q000556:secondary* / Q000601:surgery; D011379:Prognosis; D035583:Rare Diseases; D012186:Retroperitoneal Neoplasms / Q000188:drug therapy / Q000532:radiotherapy / Q000556:secondary* / Q000601:surgery; D017211:Treatment Failure