title: Does the nose know? Amitraz poisoning and olfaction.
abstract: The initial clinical presentation of amitraz and organophosphate poisoning may be similar. Reduced serum pseudocholinesterase supports a diagnosis of organophosphate toxicity, but there is no similar laboratory test for amitraz poisoning. A 'mothball-like' odour associated with poisoned patients may have diagnostic potential. In a blinded controlled trial, 83% (95% confidence interval, 63% to 93%) of 23 healthcare workers were able to distinguish between the odours of amitraz and organophosphate. Awareness of this simple component of bedside examination may allow earlier recognition of this potentially fatal poisoning.
authors.forename: Andy
authors.initials: A
authors.lastname: Parrish
authors.forename: Ruth
authors.initials: R
authors.lastname: Lancaster
mesh_terms: D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007306:Insecticides / Q000506:poisoning*; D008297:Male; D009812:Odorants; D062025:Organophosphate Poisoning; D011041:Poisoning / Q000175:diagnosis; D012680:Sensitivity and Specificity; D012903:Smell; D014052:Toluidines / Q000506:poisoning*
chemical_list: D007306:Insecticides; D014052:Toluidines; C014983:amitraz