title: Glaucogenin E, a new C21 steroid from Cynanchum stauntonii.
abstract: Glaucogenin E (1), a new C(21) steroid sapogenin, along with three known ones (2-4) were isolated from the rhizomes of Cynanchum stauntonii (Decne.) Schltr. ex Levl. Their structures were established mainly by the spectroscopic analysis, including 2D NMR. All the isolated compounds were evaluated for their cytotoxicity against human cancer cell lines HeLa, Bel-7402, SGC-7901 and BGC-823.
authors.affiliation: Department of Natural medicinal chemistry, China Pharmaceutical University, Nanjing 210009, China.
authors.forename: Mi
authors.initials: M
authors.lastname: Zhang
authors.forename: Jun-Song
authors.initials: JS
authors.lastname: Wang
authors.forename: Jun
authors.initials: J
authors.lastname: Luo
authors.forename: Dan-Dan
authors.initials: DD
authors.lastname: Wei
authors.forename: Ling-Yi
authors.initials: LY
authors.lastname: Kong
mesh_terms: D045744:Cell Line, Tumor; D049109:Cell Proliferation / Q000187:drug effects; D002681:China; D002845:Chromatography; D031105:Cynanchum / Q000737:chemistry*; D003603:Cytotoxins / Q000494:pharmacology*; D006801:Humans; D020128:Inhibitory Concentration 50; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010936:Plant Extracts / Q000032:analysis* / Q000302:isolation & purification / Q000494:pharmacology; D027343:Rhizome / Q000737:chemistry*; D012502:Sapogenins / Q000032:analysis* / Q000302:isolation & purification / Q000494:pharmacology
chemical_list: D003603:Cytotoxins; D010936:Plant Extracts; D012502:Sapogenins