title: On validation of multibody musculoskeletal models.
abstract: We review the opportunities to validate multibody musculoskeletal models in view of the current transition of musculoskeletal modelling from a research topic to a practical simulation tool in product design, healthcare and other important applications. This transition creates a new need for justification that the models are adequate representations of the systems they simulate. The need for a consistent terminology and established standards is identified and knowledge from fields with a more progressed state-of-the-art in verification and validation is introduced. A number of practical steps for improvement of the validation of multibody musculoskeletal models are pointed out and directions for future research in the field are proposed. It is hoped that a more structured approach to model validation can help to improve the credibility of musculoskeletal models.
authors.affiliation: Department of Mechanical and Manufacturing Engineering, Aalborg University, Denmark.
authors.forename: Morten Enemark
authors.initials: ME
authors.lastname: Lund
authors.forename: Mark
authors.initials: M
authors.lastname: de Zee
authors.forename: Michael Skipper
authors.initials: MS
authors.lastname: Andersen
authors.forename: John
authors.initials: J
authors.lastname: Rasmussen
mesh_terms: D003198:Computer Simulation; D006801:Humans; D007596:Joints / Q000502:physiology*; D007866:Leg / Q000502:physiology*; D008954:Models, Biological; D009068:Movement / Q000502:physiology*; D009119:Muscle Contraction / Q000502:physiology*; D018482:Muscle, Skeletal / Q000502:physiology*; D054928:Validation Studies as Topic