title: Dietary exposure to polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans and polychlorinated biphenyls of the French population: Results of the second French Total Diet Study.
abstract: Polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs) and polychlorinated biphenyls (PCBs) bioaccumulate through the food chain and are therefore of public health concern. Exposure to these compounds was assessed in the second French Total Diet Study (TDS). Food samples (n=583) were collected to be representative of the whole diet of the population, prepared as consumed, and analyzed. Contamination data were combined with national individual food consumption data. Mean exposure (95th percentile) to PCDD/F+DL-PCBs was assessed to be 0.57 (1.29) pg TEQ(WHO-98) (kg bw)(-1) d(-1) in the adult population and 0.89 (2.02) pg TEQ(WHO-98) (kg bw)(-1) d(-1) in the child and teenager population. Less than 4% of the population exceeded the health-based guidance value for PCDD/F+DL-PCBs. Mean exposure (95th percentile) to the six indicator PCBs (PCB 28, 52, 101, 138, 153, 180) was estimated at 2.71 (7.90) ng (kg bw)(-1) d(-1) in the adult population and 3.77 (11.7) ng (kg bw)(-1) d(-1) in the child and teenager population. Only 2.6% of the adults [CI(95%): 1.9; 3.3] and 6.5% of the children and teenagers [5.2; 7.8] exceeded the health-based guidance value for total PCBs. These results show that the contamination levels in food and therefore the exposure of the general French population to PCDD/Fs and PCBs have declined (by a factor of 3.2 for PCDD/F+DL-PCBs and about three for total PCBs) since the last evaluation, which was conducted using another methodology in 2005 and 2007, and show the efficiency of the European risk management measures which came into force after these evaluations.
authors.affiliation: French Agency for Food, Environmental and Occupational Health & Safety (ANSES, Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail), 27 avenue du Général Leclerc, F-94701 Maisons-Alfort, France.
authors.forename: Véronique
authors.initials: V
authors.lastname: Sirot
authors.forename: Alexandra
authors.initials: A
authors.lastname: Tard
authors.forename: Anaïs
authors.initials: A
authors.lastname: Venisseau
authors.forename: Aline
authors.initials: A
authors.lastname: Brosseaud
authors.forename: Philippe
authors.initials: P
authors.lastname: Marchand
authors.forename: Bruno
authors.initials: B
authors.lastname: Le Bizec
authors.forename: Jean-Charles
authors.initials: JC
authors.lastname: Leblanc
mesh_terms: D001572:Benzofurans / Q000032:analysis; D000072338:Dibenzofurans, Polychlorinated; D004032:Diet; D004034:Diet Surveys; D004781:Environmental Exposure / Q000032:analysis*; D004785:Environmental Pollutants / Q000032:analysis*; D005504:Food Analysis; D005506:Food Contamination / Q000032:analysis*; D005602:France; D006801:Humans; D011078:Polychlorinated Biphenyls / Q000032:analysis; D000072317:Polychlorinated Dibenzodioxins / Q000031:analogs & derivatives / Q000032:analysis
chemical_list: D001572:Benzofurans; D000072338:Dibenzofurans, Polychlorinated; D004785:Environmental Pollutants; D000072317:Polychlorinated Dibenzodioxins; D011078:Polychlorinated Biphenyls