title: Is gynecological cancer a new indication for surveillance colonoscopy in Korea?
abstract: OBJECTIVE
  Previous studies regarding the risk for colorectal neoplasms in women with a prior diagnosis of gynecological cancer have revealed conflicting results. Therefore, we conducted a cross-sectional study to quantify the risk for colorectal neoplasms in patients with gynecological cancers.
  
  
  METHODS
  A total of 4613 women (including 27, 51 and 92 women with a prior diagnosis of endometrial, ovarian and cervical cancers, respectively) >20 years of age were recruited prospectively from 9 tertiary medical centers in Korea between January 2008 and February 2009. All participants underwent complete colonoscopies for vague abdominal signs or symptoms or for colorectal cancer screening. Several risk factors for colorectal neoplasms and a prior history of gynecological cancer were compared between women with and without colorectal neoplasms.
  
  
  RESULTS
  The risk for colorectal neoplasms was only elevated among women with previous endometrial cancer, but with ovarian or cervical cancer, particularly when diagnosed at <50 years of age (adjusted OR=3.7; 95% CI=1.0-13.3, p=0.016).
  
  
  CONCLUSIONS
  This study demonstrated a higher risk for colorectal neoplasms in women with previous endometrial cancer, particularly when diagnosed at <50 years of age. Greater emphasis on colorectal cancer screening in this population may be necessary.
authors.affiliation: Kangbuk Samsung Hospital, South Korea.
authors.forename: Je Ho
authors.initials: JH
authors.lastname: Chang
authors.forename: Hyo Sun
authors.initials: HS
authors.lastname: Choi
authors.forename: Joong Sub
authors.initials: JS
authors.lastname: Choi
authors.forename: Dong Il
authors.initials: DI
authors.lastname: Park
authors.forename: Hyun Il
authors.initials: HI
authors.lastname: Seo
authors.forename: Moon Hee
authors.initials: MH
authors.lastname: Yang
authors.forename: Hee Jung
authors.initials: HJ
authors.lastname: Sohn
authors.forename: Sun Young
authors.initials: SY
authors.lastname: Lee
authors.forename: Yoon Tae
authors.initials: YT
authors.lastname: Jeen
authors.forename: Youn Tae
authors.initials: YT
authors.lastname: Jin
authors.forename: Jung Sun
authors.initials: JS
authors.lastname: Ji
authors.forename: Byung Ik
authors.initials: BI
authors.lastname: Jang
authors.forename: Jung Eun
authors.initials: JE
authors.lastname: Shin
authors.forename: Chang Soo
authors.initials: CS
authors.lastname: Eun
authors.forename: Il Hyun
authors.initials: IH
authors.lastname: Back
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D003113:Colonoscopy; D015179:Colorectal Neoplasms / Q000175:diagnosis / Q000453:epidemiology*; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D016015:Logistic Models; D008403:Mass Screening / Q000379:methods*; D008875:Middle Aged; D015999:Multivariate Analysis; D016609:Neoplasms, Second Primary / Q000175:diagnosis / Q000453:epidemiology*; D016017:Odds Ratio; D010051:Ovarian Neoplasms / Q000453:epidemiology*; D018579:Patient Selection; D011237:Predictive Value of Tests; D011446:Prospective Studies; D056910:Republic of Korea / Q000453:epidemiology; D018570:Risk Assessment; D012307:Risk Factors; D002583:Uterine Cervical Neoplasms / Q000453:epidemiology*