title: Protein transport across the cell wall of monoderm Gram-positive bacteria.
abstract: In monoderm (single-membrane) Gram-positive bacteria, the majority of secreted proteins are first translocated across the cytoplasmic membrane into the inner wall zone. For a subset of these proteins, final destination is within the cell envelope as either membrane-anchored or cell wall-anchored proteins, whereas another subset of proteins is destined to be transported across the cell wall into the extracellular milieu. Although the cell wall is a porous structure, there is evidence that, for some proteins, transport is a regulated process. This review aims at describing what is known about the mechanisms that regulate the transport of proteins across the cell wall of monoderm Gram-positive bacteria.
authors.affiliation: Department of Microbiology and Immunology, Cornell University, Ithaca, NY 14853, USA.
authors.forename: Brian M
authors.initials: BM
authors.lastname: Forster
authors.forename: Hélène
authors.initials: H
authors.lastname: Marquis
mesh_terms: D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism*; D002473:Cell Wall / Q000235:genetics / Q000378:metabolism*; D006094:Gram-Positive Bacteria / Q000235:genetics / Q000378:metabolism*; D021381:Protein Transport
chemical_list: D001426:Bacterial Proteins