title: Hereditary characteristic of isolated congenital vomer aplasia.
abstract: Malformation of the inner nose is often found in conjunction with different types of cleft palate or may be seen with severe and complex craniofacial anomalies. Among such malformations, however, isolated vomer aplasia is rarely reported in the literature. This study sets forth our findings that congenital vomeral defect of the nasal septum is an isolated disorder with hereditary characteristics. Between 2001 and 2009, nine cases of isolated congenital vomeral bone defect were detected on endoscopic examination of patients referred to our clinic with nasal and otologic complaints. The files of these patients were reviewed and vomer aplasia was identified as an isolated hereditary condition with concomitant sinonasal symptoms. The defect of the posteroinferior part of the nasal septum was defined as a genetic disease presenting with no significant medical problems. Chromosomal analysis of these patients may help to reveal the relationship of this anomaly with different malformations of the maxillofacial complex.
authors.affiliation: Department of Otorhinolaryngology/Head and Neck Surgery, Haydarpaşa Numune Educational and Research Hospital, İstanbul, Turkey. aysegulverim@hotmail.com
authors.forename: Ayşegül
authors.initials: A
authors.lastname: Verim
authors.forename: Ömer
authors.initials: Ö
authors.lastname: Faruk Çalım
authors.forename: Alper
authors.initials: A
authors.lastname: Yenigün
authors.forename: Gamze Didem
authors.initials: GD
authors.lastname: Kocagöz
authors.forename: Numan
authors.initials: N
authors.lastname: Kökten
authors.forename: Haluk
authors.initials: H
authors.lastname: Özkul
mesh_terms: D000328:Adult; D003371:Cough / Q000209:etiology; D004433:Earache / Q000209:etiology; D004724:Endoscopy; D005064:Eustachian Tube / Q000473:pathology; D005260:Female; D006261:Headache / Q000209:etiology; D034381:Hearing Loss / Q000209:etiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D015508:Nasal Obstruction / Q000209:etiology; D000857:Olfaction Disorders / Q000209:etiology; D012220:Rhinitis / Q000209:etiology; D014057:Tomography, X-Ray Computed / Q000379:methods; D055172:Vomer / Q000002:abnormalities*; D055815:Young Adult