title: Genomic analysis of emm59 group A Streptococcus invasive strains, United States.
abstract: Genomic analysis of type emm59 group A Streptococcus invasive strains isolated in the United States discovered higher than anticipated genetic heterogeneity among strains and identified a heretofore unrecognized monoclonal cluster of invasive infections in the San Francisco Bay area. Heightened monitoring for a potential shift in the epidemic behavior of emm59 group A Streptococcus is warranted.
authors.affiliation: The Methodist Hospital Research Institute, Houston, Texas 77030, USA.
authors.forename: Nahuel
authors.initials: N
authors.lastname: Fittipaldi
authors.forename: Randall J
authors.initials: RJ
authors.lastname: Olsen
authors.forename: Stephen B
authors.initials: SB
authors.lastname: Beres
authors.forename: Chris
authors.initials: C
authors.lastname: Van Beneden
authors.forename: James M
authors.initials: JM
authors.lastname: Musser
mesh_terms: D000942:Antigens, Bacterial / Q000235:genetics; D001425:Bacterial Outer Membrane Proteins / Q000235:genetics; D002352:Carrier Proteins / Q000235:genetics; D016680:Genome, Bacterial; D054643:INDEL Mutation; D058889:Molecular Typing / Q000592:standards; D010802:Phylogeny; D020641:Polymorphism, Single Nucleotide; D011159:Population Surveillance; D012015:Reference Standards; D017422:Sequence Analysis, DNA; D013290:Streptococcal Infections / Q000382:microbiology*; D013297:Streptococcus pyogenes / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification; D014481:United States
chemical_list: D000942:Antigens, Bacterial; D001425:Bacterial Outer Membrane Proteins; D002352:Carrier Proteins; C014689:streptococcal M protein