title: General and selective copper-catalyzed reduction of tertiary and secondary phosphine oxides: convenient synthesis of phosphines.
abstract: Novel catalytic reductions of tertiary and secondary phosphine oxides to phosphines have been developed. Using tetramethyldisiloxane (TMDS) as a mild reducing agent in the presence of copper complexes, PO bonds are selectively reduced in the presence of other reducible functional groups (FGs) such as ketones, esters, and olefins. Based on this transformation, an efficient one pot reduction/phosphination domino sequence allows for the synthesis of a variety of functionalized aromatic and aliphatic phosphines in good yields.
authors.affiliation: Leibniz-Institut für Katalyse e.V. an der Universität Rostock, Albert Einstein Str. 29a, 18059 Rostock, Germany.
authors.forename: Yuehui
authors.initials: Y
authors.lastname: Li
authors.forename: Shoubhik
authors.initials: S
authors.lastname: Das
authors.forename: Shaolin
authors.initials: S
authors.lastname: Zhou
authors.forename: Kathrin
authors.initials: K
authors.lastname: Junge
authors.forename: Matthias
authors.initials: M
authors.lastname: Beller