title: Impact of altitude on predicting midterm outcome in patients with ST elevation myocardial infarction.
abstract: This study investigated the effects of altitude on occurrence of mid-term negative events among patients presenting with ST elevation myocardial infarction (STEMI). This study enrolled 492 patients with STEMI. 119 of those patients were living at an intermediate altitude (1960 m, Group I) and 373 were living at sea level (0 m, Group II). There was no significant difference between the different altitude groups in terms of the incidence of cardiac death, urgent target vessel revascularization (TVR), stroke/transient ischemic attack (TIA) and composite endpoints. However, Group I had a significantly higher reinfarction incidence when compared with the Group II. Independent predictors of 6-month composite endpoints were history of statin use, presentation with acute stent thrombosis, peak CK-MB level, success of procedure, Killip classification, and left ventricular ejection fraction. In conclusion, altitude status and altitude-related hematologic changes had no influence over the mid-term outcomes in STEMI patients treated with percutaneous intervention.
authors.affiliation: Department of Cardiology, Balikesir University, School of Medicine, Balıkesir, Turkey. isikturgay@yahoo.com
authors.forename: Turgay
authors.initials: T
authors.lastname: Isık
authors.forename: Ibrahim Halil
authors.initials: IH
authors.lastname: Tanboga
authors.forename: Erkan
authors.initials: E
authors.lastname: Ayhan
authors.forename: Huseyin
authors.initials: H
authors.lastname: Uyarel
authors.forename: Ahmet
authors.initials: A
authors.lastname: Kaya
authors.forename: Mustafa
authors.initials: M
authors.lastname: Kurt
authors.forename: Ercan
authors.initials: E
authors.lastname: Erdogan
authors.forename: Mehmet
authors.initials: M
authors.lastname: Ergelen
authors.forename: Gokhan
authors.initials: G
authors.lastname: Cicek
authors.forename: Ozgur
authors.initials: O
authors.lastname: Akgul
authors.forename: Bahman
authors.initials: B
authors.lastname: Ghannadian
mesh_terms: D000531:Altitude; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000503:physiopathology* / Q000601:surgery; D062645:Percutaneous Coronary Intervention; D011446:Prospective Studies; D012307:Risk Factors; D016896:Treatment Outcome