title: Short-duration resistive exercise sustains neuromuscular function after bed rest.
abstract: OBJECTIVE
  The study's purpose was to assess the effectiveness of a short-duration three-times-weekly high-load resistive exercise program on preventing deterioration in neuromuscular function after prolonged bed rest.
  
  
  METHODS
  Twenty-four male subjects performed high-load resistive exercise (n = 8), high-load resistive exercise with whole-body vibration (n = 9), or no exercise (control, n = 9) during 60-d head-down tilt bed rest as part of the 2nd Berlin Bed Rest Study. Peak countermovement jump power and height, sit-to-stand performance, sprint time over 15 and 30 m, and leg press one-repetition maximum were measured before and after bed rest.
  
  
  RESULTS
  The exercise interventions were capable of ameliorating losses of peak countermovement jump power (P < 0.001) and height (P < 0.001), deterioration of sit-to-stand time from 45-cm (P = 0.034) and 30-cm (P < 0.001) sitting positions, increases of 15-m (P = 0.037) and 30-m (P = 0.005) sprint time, and losses of leg press one-repetition maximum (P < 0.001).
  
  
  CONCLUSIONS
  The short-duration (6-min time under tension per training session) exercise countermeasure program performed three times a week was capable of reducing the effect of prolonged bed rest on many neuromuscular function measures.
authors.affiliation: Centre for Muscle and Bone Research, Charité Universitätsmedizin Berlin, Berlin, Germany. ulf.gast@charite.de
authors.forename: Ulf
authors.initials: U
authors.lastname: Gast
authors.forename: Silke
authors.initials: S
authors.lastname: John
authors.forename: Martin
authors.initials: M
authors.lastname: Runge
authors.forename: Rainer
authors.initials: R
authors.lastname: Rawer
authors.forename: Dieter
authors.initials: D
authors.lastname: Felsenberg
authors.forename: Daniel L
authors.initials: DL
authors.lastname: Belavý
mesh_terms: D001510:Bed Rest / Q000009:adverse effects*; D015444:Exercise / Q000502:physiology*; D005081:Exercise Therapy / Q000379:methods*; D006801:Humans; D008297:Male; D018482:Muscle, Skeletal / Q000503:physiopathology*; D009133:Muscular Atrophy / Q000517:prevention & control; D011795:Surveys and Questionnaires; D013997:Time Factors; D014732:Vibration / Q000627:therapeutic use*