title: Myoid angioendothelioma of the spleen mimicking metastatic disease in a patient with rectal cancer: a radiologic-pathologic correlation.
abstract: Myoid angioendothelioma of the spleen is an uncommon, benign vascular tumor that is morphologically characterized by a composite of vascular spaces and stromal cells with myoid feature. Herein, we report a case of the myoid angioendothelioma of the spleen, concurrent with rectal adenocarcinoma. A 41-year-old woman presented with hematochezia for several weeks. Grossly, the rectal mass was a 2.5 × 2-cm ulcerative fungating lesion. The splenic mass was a 2.2 × 2-cm well-circumscribed lesion. Microscopically, the rectal mass was a well-differentiated adenocarcinoma that invaded into the pericolic adipose tissue. The splenic mass was composed of slit-like vascular spaces and fascicles of elongated stromal cells. Vascular endothelial cells were immunopositive for CD31, factor VIII-related antigen, and CD34 but negative for CD8. Stromal cells were immunopositive for smooth muscle actin but negative for desmin.
authors.affiliation: Department of Pathology, Research Institute for Clinical Medicine, Research Institute for Endocrine Sciences, Chonbuk National University Medical School, Jeonju-city, Jeonbuk, South Korea.
authors.forename: Kyu Yun
authors.initials: KY
authors.lastname: Jang
authors.forename: Myoung Ja
authors.initials: MJ
authors.lastname: Chung
authors.forename: Woo Sung
authors.initials: WS
authors.lastname: Moon
authors.forename: Myung Hee
authors.initials: MH
authors.lastname: Sohn
authors.forename: Seung Bae
authors.initials: SB
authors.lastname: Hwang
authors.forename: Min Ro
authors.initials: MR
authors.lastname: Lee
authors.forename: Ho
authors.initials: H
authors.lastname: Lee
authors.forename: Ho Sung
authors.initials: HS
authors.lastname: Park
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000556:secondary*; D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D006390:Hemangioendothelioma / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology*; D006801:Humans; D033162:Incidental Findings; D008279:Magnetic Resonance Imaging; D049268:Positron-Emission Tomography; D011859:Radiography; D012004:Rectal Neoplasms / Q000473:pathology*; D013160:Splenic Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000556:secondary