title: [Pseudohypoaldosteronisme type I: a rare cause of failure to thrive].
abstract: We report on a boy, born on term, presenting with a weight loss and a persistent failure to thrive after 10 days despite a normal behavior under bottle-feeding. The clinical examination was normal and biological assessment revealed hyponatremia with hyponatriuria, normal kaliemia and elevated aldosterone values, leading to type I pseudohypoaldosteronism diagnosis. Treatment with salt supplementation allowed growth improvement. The diagnosis was confirmed by the identification of a mutation in the mineralocorticoid receptor. This change was also found in several family members.
authors.affiliation: Service de pédiatrie, fédération médicochirurgicale de pédiatrie, centre hospitalier de Roubaix, boulevard Lacordaire, BP 359, 59056 Roubaix cedex 1, France.
authors.forename: A-F
authors.initials: AF
authors.lastname: Derache
authors.forename: S
authors.initials: S
authors.lastname: Rousseau
authors.forename: M
authors.initials: M
authors.lastname: Holder-Espinasse
authors.forename: S
authors.initials: S
authors.lastname: Bouquillon
authors.forename: S
authors.initials: S
authors.lastname: Bresson
authors.forename: H
authors.initials: H
authors.lastname: Ythier
authors.forename: P-S
authors.initials: PS
authors.lastname: Ganga-Zandzou
mesh_terms: D005183:Failure to Thrive / Q000209:etiology* / Q000235:genetics*; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D010375:Pedigree; D011546:Pseudohypoaldosteronism / Q000150:complications* / Q000235:genetics*