title: Microbial transformation of antimalarial terpenoids.
abstract: The fungal and bacterial transformation of terpenoids derived from plant essential oils, especially the sesquiterpenoid artemisinin from Artemisia annua, has produced several new candidate drugs for the treatment of malaria. Obtaining new derivatives of terpenoids, including artemisinin derivatives with increased antimalarial activity, is an important goal of research in microbial biotechnology and medicinal chemistry.
authors.affiliation: First Moscow State Medical University of I.M. Sechenov, Moscow, Russia.
authors.forename: Igor A
authors.initials: IA
authors.lastname: Parshikov
authors.forename: Alexander I
authors.initials: AI
authors.lastname: Netrusov
authors.forename: John B
authors.initials: JB
authors.lastname: Sutherland
mesh_terms: D000962:Antimalarials / Q000737:chemistry / Q000378:metabolism*; D001419:Bacteria / Q000378:metabolism*; D001711:Biotransformation; D005658:Fungi / Q000378:metabolism*; D013729:Terpenes / Q000737:chemistry / Q000378:metabolism*
chemical_list: D000962:Antimalarials; D013729:Terpenes