title: Hemolytic anemia in adults: main causes and diagnostic procedures.
abstract: Hemolytic anemia is not an exceptional situation in adults. Although establishing the hemolytic mechanism of an anemia is usually rather easy, finding the etiology may be quite difficult as both hereditary (corpuscular) and acquired causes of hemolytic anemia may occur during adulthood. The diagnosis of hemolytic anemia, therefore, requires a multistep procedure taking into account both the patient's and family history, a careful analysis of the blood smear and a direct antiglobulin test. Based on these first data, the diagnostic procedure may then require more specific tests whose indications are discussed in this review.
authors.affiliation: Department of Internal Medicine, National Referal Center for Adults' Immune Cytopenias, Henri Mondor University Hospital, Assistance Publique Hôpitaux de Paris, Université Paris Est Créteil, Créteil, France.
authors.forename: Constance
authors.initials: C
authors.lastname: Guillaud
authors.forename: Valentine
authors.initials: V
authors.lastname: Loustau
authors.forename: Marc
authors.initials: M
authors.lastname: Michel
mesh_terms: D000743:Anemia, Hemolytic / Q000175:diagnosis* / Q000209:etiology*; D003298:Coombs Test; D064420:Drug-Related Side Effects and Adverse Reactions; D004912:Erythrocytes / Q000201:enzymology; D004913:Erythrocytes, Abnormal; D006801:Humans; D008288:Malaria / Q000150:complications; D008565:Membrane Proteins / Q000235:genetics / Q000378:metabolism; D057049:Thrombotic Microangiopathies / Q000209:etiology
chemical_list: D008565:Membrane Proteins