title: High incidence of bacteriuria in early post-kidney transplantation; results from a randomized controlled study.
abstract: Since the incidence of bacteriuria in kidney transplant recipients varyes according to the study, we examined it among our cases. Our post hoc analysis of data from a single-center, parallel, randomized, controlled, open label study included 90 patients who underwent kidney transplantation at our hospital from April 2010 to January 2011. Patients were randomized to early ureteric stent removal at 8 days versus routine ureteric stent removal at 15 days after kidney transplantation. We identified the incidence of and causative organism for bacteriuria in the early posttransplant period. Seventy-Four patients (58% living donors) participated in this study. The overall incidence of bacteriuria was 56.7% during the first month after kidney transplantation. In patients who had bacteriuria, 48% showed symptomatic urinary tract infection, 40% asymptomatic bacteriuria and 12% urosepsis. The most common organism was Escherichia coli (40%) follow by Klebsiella pneumoniae (19%). The incidence of an ESBL producing organism was 34%. The incidence of bacteriuria was high during the early post-kidney transplant period, requiring increased awareness and surveillance.
authors.affiliation: Department of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand. gnot1234@hotmail.com
authors.forename: W
authors.initials: W
authors.lastname: Parapiboon
authors.forename: A
authors.initials: A
authors.lastname: Ingsathit
authors.forename: S
authors.initials: S
authors.lastname: Jirasiritham
authors.forename: V
authors.initials: V
authors.lastname: Sumethkul
mesh_terms: D000328:Adult; D001437:Bacteriuria / Q000453:epidemiology*; D005260:Female; D006801:Humans; D015994:Incidence; D016030:Kidney Transplantation / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D015607:Stents; D014513:Ureter