title: [Direct determination of 21 elements in serum by dynamic reaction cell inductively coupled plasma mass spectrometry].
abstract: OBJECTIVE
  To establish a method to directly determine 21 elements in serum by dynamic reaction cell inductively coupled plasma mass spectrometry (DRC-ICP-MS).
  
  
  METHODS
  The serum samples were diluted with 1% nitric acid by 3 times. The inductively coupled plasma mass spectrometry (ICP-MS) was used simultaneously to detect the serum concentrations of 21 elements (Be, Al, Mn, V, Cr, Fe, Co, Ni, Cu, Zn, As, Se, Mo, Ag, Cd, Sb, Ba, T1, Ph, Th, U).
  
  
  RESULTS
  The detection limits of all elements were between 0.001-0.0711 g/1. Standard linear correlation coefficients (r) were 50.999. Standard deviations were less than 5%,the recovery rates were 90%-114%. Standard reference materials were used for quality control standards and the analysis results conformed with the certified values.
  
  
  CONCLUSIONS
  The present method is a simple, rapid,sensitive and accurate method for detecting the serum samples.
authors.affiliation: Department of Occupationgl Disease and Toxication, Chaoyang Hospital Affiliated to the Capital University of Medical Science, Beijing 100020, China.
authors.forename: Hui-ling
authors.initials: HL
authors.lastname: Li
authors.forename: Jing
authors.initials: J
authors.lastname: Ma
authors.forename: Yang
authors.initials: Y
authors.lastname: Zhang
mesh_terms: D006801:Humans; D057230:Limit of Detection; D013058:Mass Spectrometry / Q000379:methods*; D044967:Serum / Q000737:chemistry*; D013057:Spectrum Analysis / Q000379:methods*; D014131:Trace Elements / Q000097:blood*
chemical_list: D014131:Trace Elements