title: Gemifloxacin.
abstract: A comprehensive profile on Gemifloxacin, a novel fluoroquinolone synthetic broad-spectrum antibacterial agent for oral administration, particularly indicated for treatment of community-acquired respiratory tract infections, such as pneumonia and acute bacterial exacerbations of chronic bronchitis, is prepared. This profile contains the following sections: introduction, general physicochemical informations, X-ray powder diffraction patterns, methods of preparations, methods of analysis and stability, spectroscopic methods of investigations, and identifications including ultraviolet/visible spectroscopy, infrared (vibrational) spectroscopy, proton and carbon-13 nuclear magnetic resonance spectrometry, and mass spectrometry. Section 7 includes compendial BP identification methods, thin-layer chromatography, gas chromatography, high performance liquid chromatography. The pharmacological applications section includes uses, mode of action, pharmacokinetics, and toxicity investigations.
authors.affiliation: Department of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, Kingdom of Saudi Arabia.
authors.forename: Badraddin M H
authors.initials: BM
authors.lastname: Al-Hadiya
authors.forename: Ashraf M M
authors.initials: AM
authors.lastname: Mahmoud