title: [Effect of moxibustion on motility, absorption and content of ATP in small intestine of spleen-deficiency rats].
abstract: OBJECTIVE
  To explore the mechanism of reinforcing function of moxibustion to spleen-stomach.
  
  
  METHODS
  Forty healthy Sprague Dawley rats were randomly divided into 4 groups: group A (blank group), group B (model group), group C (moxibustion group) and group D (herbs group). The rat model of spleen-deficiency was established by intragastric administration with 200% Dahuang (Rhubarb) infusion. The rats in group A and B, and D served as the blank control, model, and Sijunzi decoction group respectively, while those in group C received moxibustion at "Zusanli" (ST 36), "Zhongwan" (CV 12), "Guanyuan" (CV 4), "Pishu" (BL 20) and "Weishu" (BL 21), etc. The common symptoms and intestinal propulsive rate were observed. The content of I-xylose in serum was detected by phloroglucinol method. Colorimetry method was used to detected content of ATP in jejunum tissues.
  
  
  RESULTS
  Compared with group A, the symptom score in group B was increased significantly (both P < 0.01), while the intestinal propulsive rates, the content of D-xylose in serum and ATP in jejunum tissues were decreased significantly (P < 0.05, P < 0.01). Compared with group B, the symptom score in group C and D was decreased significantly (both P < 0.01), while the intestinal propulsive rates, the content of D-xylose in serum and ATP in jejunum tissues were increased significantly (P < 0.05, P < 0.01). There were no significant difference between group C and D (P > 0.05).
  
  
  CONCLUSIONS
  Moxibustion at "Zusanli" (ST 36) etc. could relieve symptoms of spleen-deficiency, enhance motility and absorption functions of small intestine and improve metabolism of small intestine. The efficacy is equal to administration of Sijunzi decoction.
authors.affiliation: College of Acupuncture-Moxibustion and Massage, Hunan University of TCM, Major Laboratory of Meridians and Viscera, Tertiary Laboratory of State Administration of TCM, Changsha 410007, China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Peng
authors.forename: Fen
authors.initials: F
authors.lastname: Peng
authors.forename: Shou-Xiang
authors.initials: SX
authors.lastname: Yi
authors.forename: Ya-Ping
authors.initials: YP
authors.lastname: Lin
authors.forename: Xiao-Rong
authors.initials: XR
authors.lastname: Chang
authors.forename: Yi-Wen
authors.initials: YW
authors.lastname: Long
authors.forename: Hong-Guo
authors.initials: HG
authors.lastname: Zhang
mesh_terms: D000255:Adenosine Triphosphate / Q000378:metabolism*; D000818:Animals; D005260:Female; D006801:Humans; D007408:Intestinal Absorption; D007421:Intestine, Small / Q000378:metabolism / Q000503:physiopathology*; D008297:Male; D009071:Moxibustion; D051381:Rats; D017207:Rats, Sprague-Dawley; D013154:Spleen / Q000503:physiopathology*; D013158:Splenic Diseases / Q000378:metabolism / Q000503:physiopathology / Q000628:therapy*
chemical_list: D000255:Adenosine Triphosphate