title: Mortality and serum sodium in  CKD--yet another U‑shaped curve.
abstract: A consistent association between hyponatremia and increased mortality has been shown in hospitalized patients. A new study investigating dysnatremia in non-dialysis-dependent patients with chronic kidney disease found that both hyponatremia and hypernatremia are associated with increased mortality, independently of other diseases known to cause hyponatremia.
authors.affiliation: Division of Renal Diseases and Hypertension, University of Colorado, Aurora, CO 80045, USA.
authors.forename: Anna
authors.initials: A
authors.lastname: Jovanovich
authors.forename: Tomas
authors.initials: T
authors.lastname: Berl
mesh_terms: D006801:Humans; D006955:Hypernatremia / Q000401:mortality*; D007010:Hyponatremia / Q000401:mortality*; D053208:Kaplan-Meier Estimate; D007676:Kidney Failure, Chronic / Q000401:mortality*; D015999:Multivariate Analysis