title: Biochemical changes in pig serum after ochratoxin A exposure.
abstract: The objective of this study was to investigate the effect of ochratoxin A (OTA) on serum biochemical parameters of pigs during subchronic treatment with 300 μg OTA/kg of feed for 30 days. OTA treatment resulted in significantly higher (p < 0.05) serum levels of creatinine, urea, potassium and alkaline phosphatase, and significantly lower levels of glucose and total protein. These changes in serum biochemical parameters in treated pigs were indicative of impaired liver and kidney function caused by OTA exposure.
authors.affiliation: Department of Veterinary Public Health, Croatian Veterinary Institute, Savska 143, 10000, Zagreb, Croatia. pleadin@veinst.hr
authors.forename: Jelka
authors.initials: J
authors.lastname: Pleadin
authors.forename: Nina
authors.initials: N
authors.lastname: Perši
authors.forename: Mario
authors.initials: M
authors.lastname: Mitak
authors.forename: Svjetlana
authors.initials: S
authors.lastname: Terzić
authors.forename: Dinka
authors.initials: D
authors.lastname: Milić
authors.forename: Ana
authors.initials: A
authors.lastname: Vulić
authors.forename: Mate
authors.initials: M
authors.lastname: Brstilo
mesh_terms: D000410:Alanine Transaminase / Q000097:blood; D000469:Alkaline Phosphatase / Q000097:blood; D000818:Animals; D001663:Bilirubin / Q000097:blood; D001786:Blood Glucose / Q000378:metabolism; D002273:Carcinogens / Q000633:toxicity*; D003404:Creatinine / Q000097:blood; D008297:Male; D009793:Ochratoxins / Q000633:toxicity*; D012709:Serum Albumin / Q000378:metabolism; D012712:Serum Globulins / Q000378:metabolism; D013552:Swine / Q000097:blood*; D014508:Urea / Q000097:blood; D000516:alpha-Amylases / Q000097:blood
chemical_list: D001786:Blood Glucose; D002273:Carcinogens; D009793:Ochratoxins; D012709:Serum Albumin; D012712:Serum Globulins; C025589:ochratoxin A; D014508:Urea; D003404:Creatinine; D000410:Alanine Transaminase; D000469:Alkaline Phosphatase; D000516:alpha-Amylases; D001663:Bilirubin