title: [Clinicopathological features of 8 patients with metastatic gastric tumors].
abstract: We examined the clinicopathological features of metastatic gastric tumor, using 9 tumors of 8 patients. Histological diagnosis with all biopsy specimens were adenocarcinoma. Most of the metastatic sites were located in the middle or upper gastric corpus. Endoscopic features of the lesion showed a submucosal tumor-like (5 cases) and primary gastric cancer-like (3 cases) appearance. Immunohistochemical staining of cytokeratins, TTF-1, surfactant protein, ER, or MGB1 identified the primary site; 6 in the lung and 2 in the breast. One case was diagnosed based on the EGFR mutation analysis. In conclusion, immunohistochemical staining and molecular method are useful tools to distinguish metastatic gastric tumor from primary gastric cancer.
authors.affiliation: Department of Gastroenterology, Aichi Cancer Center Hospital.
authors.forename: Asana
authors.initials: A
authors.lastname: Akabane
authors.forename: Masahiro
authors.initials: M
authors.lastname: Tajika
authors.forename: Shinya
authors.initials: S
authors.lastname: Kondo
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Tanaka
authors.forename: Nobumasa
authors.initials: N
authors.lastname: Mizuno
authors.forename: Kazuo
authors.initials: K
authors.lastname: Hara
authors.forename: Susumu
authors.initials: S
authors.lastname: Hijioka
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Imaoka
authors.forename: Akira
authors.initials: A
authors.lastname: Saeki
authors.forename: Takeshi
authors.initials: T
authors.lastname: Ogura
authors.forename: Shin
authors.initials: S
authors.lastname: Haba
authors.forename: Yoshikuni
authors.initials: Y
authors.lastname: Nagashio
authors.forename: Toshiyuki
authors.initials: T
authors.lastname: Hasegawa
authors.forename: Tomohiko
authors.initials: T
authors.lastname: Oobayashi
authors.forename: Akihide
authors.initials: A
authors.lastname: Shinagawa
authors.forename: Kenji
authors.initials: K
authors.lastname: Yamao
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Yatabe
authors.forename: Yasumasa
authors.initials: Y
authors.lastname: Niwa
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology* / Q000556:secondary*; D000368:Aged; D001706:Biopsy; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D013274:Stomach Neoplasms / Q000473:pathology* / Q000556:secondary*