title: The Evolution of Dieulafoy's Lesion Since 1897: Then and Now-A Journey through the Lens of a Pediatric Lesion with Literature Review.
abstract: Background. In 1897, Dieulafoy was the first to characterize a gaping arteriole within the gastric mucosa causing massive hematemesis, designating it as "exulceratio simplex." A hundred years later, this vascular abnormality, now commonly referred to as a "Dieulafoy lesion," has been identified through the entire gastrointestinal tract and the bronchus. Objectives and Methods. As the original findings have been subjected to revisions and modifications by modern authors, Dieulafoy's original paper was reviewed and analyzed. The evolution of the current usage of "Dieulafoy's lesion" in the literature has been summarized with comparisons to the original report. Additionally, an index case of a 10-year-old female with a gastric "exulceratio simplex" is reported with a review of previously reported paediatric Dieulafoy lesions. Conclusions. The term "Dieulafoy lesion" in modern literature no longer adheres to the initial conclusions with regards to its origin, demographics, and presenting symptoms. Dieulafoy lesions remain a rare cause of gastrointestinal bleeding that can cause life-threatening haemorrhages in children.
authors.affiliation: Department of Pathology and Laboratory Medicine, Royal University Hospital, University of Saskatchewan, Saskatoon SK, Canada S7N 0W8.
authors.forename: Jenna-Lynn
authors.initials: JL
authors.lastname: Senger
authors.forename: Rani
authors.initials: R
authors.lastname: Kanthan