title: Torsade de Pointes and Persistent QTc Prolongation after Intravenous Amiodarone.
abstract: We report a case of torsade de pointes after intravenous amiodarone and concurrent hypokalemia. Despite treatment cessation and correction of electrolyte abnormalities, excessive QTc prolongation was noted, which persisted for 14 days. This prolonged course for QTc normalization may be attributed to the high rate of amiodarone loading and concurrent electrolyte disturbances coupled with possible underlying individual variability in pharmacokinetics.
authors.affiliation: Department of Cardiology, University Hospital of Ioannina, 1 Stavrou Niarxou Avenue, 45110 Ioannina, Greece.
authors.forename: Anna P
authors.initials: AP
authors.lastname: Kotsia
authors.forename: Georgios
authors.initials: G
authors.lastname: Dimitriadis
authors.forename: Giannis G
authors.initials: GG
authors.lastname: Baltogiannis
authors.forename: Theofilos M
authors.initials: TM
authors.lastname: Kolettis