title: [Standardised scoring of a multi-parametric 3-T MRI for a targeted MRI-guided prostate biopsy].
abstract: BACKGROUND
  The use of multi-parametric MRI and MRI-guided biopsy for the detection of prostate cancer is rapidly increasing. This is a pilot study to evaluate the consensus-based international MRI scoring system as decision criterion for targeted MRI-guided prostate biopsy.
  
  
  METHODS
  After a multi-parametric 3-T MRI (T2-weighted imaging, diffusion-weighted imaging, and dynamic contrast-enhanced MRI) in 23 consecutive patients a total of 47 lesions were scored according to a 5-point scale for each MRI sequence. A total score of ≥ 10 points was considered to be suspicious for prostate cancer. All 47 lesions were histologically assessed after MRI-guided biopsy.
  
  
  RESULTS
  At the cut-off score of 10 points, sensitivity, specificity, negative predictive value and positive predictive value of multi-parametric MRI were 94.1, 43.3, 92.9 and 48.5%, respectively.
  
  
  CONCLUSIONS
  A standardised scoring of lesions on multi-parametric MRI is feasible. The cut-off value leads to excellent values for sensitivity and negative predictive value. The values for specificity and positive predictive value are modest. Lesions with a total score <10 points are very unlikely to be malignant.
authors.affiliation: Klinik für Urologie, Universitätsklinikum Düsseldorf, Düsseldorf.
authors.forename: C
authors.initials: C
authors.lastname: Arsov
authors.forename: D
authors.initials: D
authors.lastname: Blondin
authors.forename: R
authors.initials: R
authors.lastname: Rabenalt
authors.forename: G
authors.initials: G
authors.lastname: Antoch
authors.forename: P
authors.initials: P
authors.lastname: Albers
authors.forename: M
authors.initials: M
authors.lastname: Quentin
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001707:Biopsy, Needle / Q000592:standards*; D006801:Humans; D007090:Image Interpretation, Computer-Assisted / Q000592:standards*; D038622:Internationality; D008279:Magnetic Resonance Imaging / Q000592:standards*; D008297:Male; D008875:Middle Aged; D011471:Prostatic Neoplasms / Q000473:pathology*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D025321:Surgery, Computer-Assisted / Q000592:standards*