title: Three cases of idiopathic sterile pyogranulomatous inflammation of epidural fat in Miniature Dachshunds.
abstract: Progressive ataxia and paralysis in three Miniature Dachshunds were found to be caused by idiopathic sterile pyogranulomatous inflammation of epidural fat between T5 and L4. All dogs were managed by hemilaminectomy and removal of epidural compressive material. Surgical findings and histopathological evaluation were necessary to diagnose epidural pyogranulomatous inflammation. A dog did not regain motor and sensor function after the surgery. Two dogs had exhibited improved neurological function after the surgery, but they recurred. Oral cyclosporine treatment was useful for their long remission. Idiopathic sterile pyogranulomatous inflammation of epidural fat can be considered to be a cause of thoracolumbar myelopathy in dogs.
authors.affiliation: Nakayama Veterinary Hospital, 6-1 Minamifukuro, Nara, Nara 630-8342, Japan.
authors.forename: Hidetaka
authors.initials: H
authors.lastname: Nishida
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Tanaka
authors.forename: Masahiko
authors.initials: M
authors.lastname: Kitamura
authors.forename: Shingo
authors.initials: S
authors.lastname: Hatoya
authors.forename: Kikuya
authors.initials: K
authors.lastname: Sugiura
authors.forename: Toshio
authors.initials: T
authors.lastname: Inaba
authors.forename: Masanari
authors.initials: M
authors.lastname: Nakayama
mesh_terms: D000273:Adipose Tissue / Q000473:pathology*; D000818:Animals; D016572:Cyclosporine / Q000627:therapeutic use; D004283:Dog Diseases / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D004285:Dogs; D005260:Female; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007249:Inflammation / Q000188:drug therapy / Q000473:pathology / Q000601:surgery / Q000662:veterinary*; D007796:Laminectomy / Q000379:methods / Q000662:veterinary*; D008297:Male; D011239:Prednisolone / Q000627:therapeutic use
chemical_list: D007166:Immunosuppressive Agents; D016572:Cyclosporine; D011239:Prednisolone