title: [Acute postinfectious glomerulonephritis].
abstract: Acute postinfectious glomerulonephritis are defined by an acute nonsuppurative inflammatory insult predominantly glomerular. Its current incidence is uncertain because of the frequency of subclinical forms. The most common infectious agent involved is beta hemolytic streptococcus group A. Acute postinfectious glomerulonephritis is uncommon in adults, and its incidence is progressively declining in developed countries. Humoral immunity plays a key role in the pathogenesis of kidney damage. Complement activation by the alternative pathway is the dominant mechanism, but a third way (lectin pathway) has been recently identified. The classic clinical presentation is sudden onset of acute nephritic syndrome after a free interval from a streptococcal infection. Treatment is essentially symptomatic and prevention is possible through improved hygiene and early treatment of infections.
authors.affiliation: Service de Néphrologie Hémodialyse, Centre Hospitalier Ibn-Rochd, Casablanca, Maroc. benyounsramdani@gmail.com
authors.forename: Benyounès
authors.initials: B
authors.lastname: Ramdani
authors.forename: Mohamed
authors.initials: M
authors.lastname: Zamd
authors.forename: Khadija
authors.initials: K
authors.lastname: Hachim
authors.forename: Kenza
authors.initials: K
authors.lastname: Soulami
authors.forename: Madiha
authors.initials: M
authors.lastname: Ezzahidy
authors.forename: Malika
authors.initials: M
authors.lastname: Souiri
authors.forename: Wafaa
authors.initials: W
authors.lastname: Fadili
authors.forename: Assia
authors.initials: A
authors.lastname: Lahboub
authors.forename: Leila
authors.initials: L
authors.lastname: Hanafi
authors.forename: Meryem
authors.initials: M
authors.lastname: Boujida
authors.forename: Saida
authors.initials: S
authors.lastname: Squalli
authors.forename: Amal
authors.initials: A
authors.lastname: Benkirane
authors.forename: Mohamed Gharbi
authors.initials: MG
authors.lastname: Benghanem
authors.forename: Ghizlane
authors.initials: G
authors.lastname: Medkouri
mesh_terms: D000208:Acute Disease; D000328:Adult; D002648:Child; D003167:Complement Activation; D005260:Female; D005921:Glomerulonephritis / Q000209:etiology* / Q000276:immunology / Q000473:pathology; D006801:Humans; D007678:Kidney Glomerulus / Q000473:pathology*; D008297:Male; D013290:Streptococcal Infections / Q000150:complications* / Q000276:immunology; D013297:Streptococcus pyogenes