title: Uterine carcinosarcoma associated with pelvic radiotherapy for sacral chordoma: a case report.
abstract: OBJECTIVE
  Postirradiation sarcoma of the female genital tract is rare, but a recognized event. Most reported cases have been associated with history of radiotherapy for various gynecologic conditions, particularly cancer of the uterine cervix and abnormal uterine bleeding. The occurrence of uterine sarcoma secondary to radiotherapy for a non-gynecologic tumor and, furthermore, this condition being simultaneous with the recurrence of primary tumor is unique.
  
  
  METHODS
  A 67-year-old woman presented with a uterine mass which was diagnosed as a sarcoma by endometrial curettage and history of pelvic radiotherapy 23 years previously for sacral chordoma. Surgical staging procedure for uterine malignancy was performed. The final pathologic diagnosis was carcinosarcoma of the uterus.
  
  
  CONCLUSIONS
  In uterine masses seen in patients with history of irradiation to the pelvic field, the probability of uterine sarcomas should always be kept in mind. These tumors may occur simultaneously with recurrence of primary tumor previously treated by adjuvant radiation therapy.
authors.affiliation: Department of Obstetrics and Gynecology, Ankara University School of Medicine, Ankara, Turkey. korhankahraman@hotmail.com
authors.forename: Korhan
authors.initials: K
authors.lastname: Kahraman
authors.forename: Fırat
authors.initials: F
authors.lastname: Ortac
authors.forename: Duygu
authors.initials: D
authors.lastname: Kankaya
authors.forename: Gulsah
authors.initials: G
authors.lastname: Aynaoglu
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D016190:Carboplatin / Q000008:administration & dosage; D002296:Carcinosarcoma / Q000188:drug therapy / Q000209:etiology* / Q000601:surgery; D017024:Chemotherapy, Adjuvant; D002817:Chordoma / Q000532:radiotherapy* / Q000601:surgery; D005260:Female; D006801:Humans; D009364:Neoplasm Recurrence, Local / Q000601:surgery*; D009381:Neoplasms, Radiation-Induced / Q000601:surgery*; D017239:Paclitaxel / Q000008:administration & dosage; D012445:Sacrococcygeal Region; D014594:Uterine Neoplasms / Q000188:drug therapy / Q000209:etiology* / Q000601:surgery
chemical_list: D016190:Carboplatin; D017239:Paclitaxel