title: Localized nasopharyngeal amyloidosis.
abstract: OBJECTIVE
  To illustrate, via a case report, how a differential diagnosis of amyloidosis is to be suspected in case of a nasopharyngeal mass.
  
  
  METHODS
  A 59-year-old woman presented with bilateral nasal obstruction with associated episodic tubal dysfunction. Physical examination found a mass occupying the entire nasopharynx, initially suggestive of tumor.
  
  
  CONCLUSIONS
  Amyloidosis was diagnosed on histopathologic study of the biopsy and surgical specimens. Exploration for systemic disease proved negative. The localized amyloidosis was managed conservatively. At 9 months' follow-up, there was no recurrence.
  
  
  CONCLUSIONS
  Localized amyloidosis, however rare, should be considered as differential diagnosis in any case of nasal obstruction with tubal dysfunction, even if bilateral. ENT physicians need to recognize and understand this pathology for adapted diagnostic and treatment planning.
authors.affiliation: Département d'otorhinolaryngologie et de chirurgie cervico-faciale, université Claude-Bernard Lyon I, hôpital de la Croix-Rousse, 93, Grande-rue-de-la-Croix-Rousse, 69317 Lyon cedex 04, France. mickael.durbec@hotmail.fr
authors.forename: M
authors.initials: M
authors.lastname: Durbec
authors.forename: A
authors.initials: A
authors.lastname: Ambrun
authors.forename: R
authors.initials: R
authors.lastname: Barnoud
authors.forename: M
authors.initials: M
authors.lastname: Poupart
authors.forename: J-C
authors.initials: JC
authors.lastname: Pignat
authors.forename: O
authors.initials: O
authors.lastname: Merrot
mesh_terms: D000686:Amyloidosis / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D001706:Biopsy; D003287:Contrast Media / Q000008:administration & dosage; D003937:Diagnosis, Differential; D005260:Female; D005682:Gadolinium; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D009302:Nasopharyngeal Diseases / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D009303:Nasopharyngeal Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D009305:Nasopharynx / Q000473:pathology / Q000601:surgery; D014057:Tomography, X-Ray Computed
chemical_list: D003287:Contrast Media; D005682:Gadolinium