title: The expression of aquaporin 1 and 5 in uterine leiomyomata in premenopausal women: a preliminary study.
abstract: The aim of this study was to investigate the expression of aquaporins (AQPs) in uterine tissues of premenopausal women. We demonstrated for the first time the expression of AQP1, AQP5 and AQP9 in uterine leiomyomata and in the adjacent normal endometrium and myometrium. The expression of AQP1 and 5 was higher in leiomyomata than in unaffected uteri. AQP9 was expressed only in the unaffected endometrium. It is possible that AQP1 and AQP5 contribute to the formation of leiomyomata in premenopausal women.
authors.affiliation: Department of Animal Physiology, University of Warmia and Mazury, Olsztyn, Poland. skowron@uwm.edu.pl
authors.forename: Mariusz T
authors.initials: MT
authors.lastname: Skowronski
authors.forename: Leszek
authors.initials: L
authors.lastname: Frackowiak
authors.forename: Agnieszka
authors.initials: A
authors.lastname: Skowronska
mesh_terms: D000328:Adult; D051398:Aquaporin 1 / Q000032:analysis*; D051402:Aquaporin 5 / Q000032:analysis*; D020346:Aquaporins / Q000032:analysis; D015153:Blotting, Western; D004717:Endometrium / Q000737:chemistry; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D007889:Leiomyoma / Q000737:chemistry*; D008875:Middle Aged; D009215:Myometrium / Q000737:chemistry; D017697:Premenopause; D014594:Uterine Neoplasms / Q000737:chemistry*; D014599:Uterus / Q000737:chemistry
chemical_list: C109669:AQP9 protein, human; D051402:Aquaporin 5; D020346:Aquaporins; D051398:Aquaporin 1