title: Current Pharmacological Management in Juvenile Huntington's Disease.
abstract: BACKGROUND
  The clinical presentation of Juvenile Huntington's Disease (JHD) can be very different from adult-onset HD with little evidence to guide symptomatic management.
  
  
  OBJECTIVE
  To survey the current use of pharmacological treatments for JHD.
  
  
  METHODS
  Patients were identified through the HD Association, Hospital Doctors and the European Huntington's Disease Network REGISTRY study.
  
  
  RESULTS
  The most commonly prescribed agents were anti-psychotics (24/45), anti-depressants (17/45) and anti-parkinsonian medications (15/45). 5 patients were taking more than 8 medications.
  
  
  CONCLUSIONS
  The most commonly prescribed group of medication was the anti-psychotic. Many patients were on multiple therapies, highlighting the need to rationalise medications.
authors.affiliation: Department of Clinical Genetics, Sheffield Children's Hospital, Sheffield UK S10 2TH;  Neurogenetics and Rare Diseases Centre, IRCCS Neuromed, Pozzilli (IS), Italy.;  University of Cambridge;  Department of Clinical Neurophysiology, Institute of Psychiatry and Naurology, Warsaw, Poland and  Dept. of Neurology, University of Ulm, Ulm, Germany.
authors.forename: Lisa
authors.initials: L
authors.lastname: Robertson
authors.forename: Helen
authors.initials: H
authors.lastname: Santini
authors.forename: Kirsty L
authors.initials: KL
authors.lastname: O'Donovan
authors.forename: Ferdinando
authors.initials: F
authors.lastname: Squitieri
authors.forename: Roger A
authors.initials: RA
authors.lastname: Barker
authors.forename: Maria
authors.initials: M
authors.lastname: Rakowicz
authors.forename: G Bernhard
authors.initials: GB
authors.lastname: Landwehrmeyer
authors.forename: Oliver
authors.initials: O
authors.lastname: Quarrell