title: Hepatic hemodynamics and transient elastography in alcoholic foamy degeneration: report of 2 cases.
abstract: Alcoholic liver disease (ALD) covers a wide spectrum of pathology ranging from fatty liver disease to acute steatohepatitis to cirrhosis and/or hepatocellular carcinoma. Alcoholic foamy degeneration (AFD) is an uncommon, potentially life-threatening condition that is part of the spectrum of ALD. It is characterized by extensive microvesicular steatosis in the perivenular areas. Since the first description in 1983, few case reports have been described. Here, we report 2 cases of AFD in patients with a previous history of chronic alcohol abuse and histological diagnosis of AFD with typical clinical, biochemical and histological features. In both cases we provide data on the hepatic hemodynamic status, and in one of them we report liver elastography results, which are features that have not been described previously. In both cases there was rapid resolution of biochemical and clinical abnormalities after complete abstinence, which is the mainstay of treatment for AFD.
authors.affiliation: Liver Unit, Hospital Clinic, Institut d'Investigaciones Biomèdiques August Pi i Sunyer, Barcelona, Spain.
authors.forename: Pablo
authors.initials: P
authors.lastname: Ruiz
authors.forename: Javier
authors.initials: J
authors.lastname: Michelena
authors.forename: José
authors.initials: J
authors.lastname: Altamirano
authors.forename: Rosa
authors.initials: R
authors.lastname: Miquel
authors.forename: Leticia
authors.initials: L
authors.lastname: Moreira
authors.forename: Andrés
authors.initials: A
authors.lastname: Cárdenas
authors.forename: Juan G
authors.initials: JG
authors.lastname: Abraldes
authors.forename: Miquel
authors.initials: M
authors.lastname: Brugera
authors.forename: Vicente
authors.initials: V
authors.lastname: Arroyo
authors.forename: Pere
authors.initials: P
authors.lastname: Ginès
authors.forename: Juan
authors.initials: J
authors.lastname: Caballería
authors.forename: Ramón
authors.initials: R
authors.lastname: Bataller
mesh_terms: D000328:Adult; D000437:Alcoholism / Q000150:complications; D001706:Biopsy; D004548:Elasticity / Q000502:physiology*; D054459:Elasticity Imaging Techniques; D006439:Hemodynamics / Q000502:physiology*; D006801:Humans; D008099:Liver / Q000098:blood supply* / Q000473:pathology / Q000503:physiopathology*; D008108:Liver Diseases, Alcoholic / Q000097:blood / Q000175:diagnosis / Q000503:physiopathology*; D008297:Male; D000637:Transaminases / Q000097:blood
chemical_list: D000637:Transaminases