title: Disentangling diffusion information of individual components in a mixture with a 3D COMPACT-IDOSY NMR experiment.
abstract: A new 3D diffusion-ordered heteronuclear NMR experiment COMPACT-IDOSY (cross-polarization optimized multisite polarized accelerated time internally encoded diffusion ordered spectroscopy) has been designed and experimentally implemented on a mixture of flavonoids rutin and quercetin. The pulse sequence uses a cross-polarization mixing period and diffusion encoding gradients internally incorporated into the coherence transfer interval of a long-range heteronuclear correlation experiment. Substantial reduction in experimental time, good sensitivity and excellent resolution of signal overlap lead to the accurate determination of translational diffusion coefficients of individual components in the mixture.
authors.affiliation: Department of Physics, Indian Institute of Science Education & Research (IISER) Mohali, Sector 81 Manauli PO, SAS Nagar, 140306, Punjab, India.
authors.forename: Matsyendranath
authors.initials: M
authors.lastname: Shukla
authors.forename: Kavita
authors.initials: K
authors.lastname: Dorai
mesh_terms: D045424:Complex Mixtures / Q000737:chemistry*; D004058:Diffusion; D005419:Flavonoids / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D011794:Quercetin / Q000737:chemistry*; D012431:Rutin / Q000737:chemistry*
chemical_list: D045424:Complex Mixtures; D005419:Flavonoids; D012431:Rutin; D011794:Quercetin