title: The use of collatamp in total hip arthroplasty.
abstract: Total Hip Arthroplasty (THA) is one of the most common orthopedic operations in the world. The number of THA is expected to grow and with it the number of associated complications. Although improved surgical technique and the development of more scrupulous asepsis has decreased the incidence of periprosthetic joint infection (PJI), it remains one of the most feared complications of joint arthroplasty. The purpose of this study is to present the use of antibiotic-loaded collagen sponges (Collatamp EG) in the prophylaxis and treatment of PJI. For this scope a case report is described. The advantages offered by the antibiotic loaded sponges in terms of high and sustained concentration of antibiotic at the site of infection, diffused by the fully reabsorbable carrier, showed to be a an important adjuvant therapy in the treatment of PJI. Low systemic concentration of the drug and a wide versatility in surgical application are other advantages of this dispositive.
authors.affiliation: Department of Ortopaedics, Catholic University of Rome, Policlinico A. Gemelli, Rome, Italy. G.Logroscino@fastwebnet.it
authors.forename: G
authors.initials: G
authors.lastname: Logroscino
authors.forename: G
authors.initials: G
authors.lastname: Malerba
authors.forename: E
authors.initials: E
authors.lastname: Pagano
authors.forename: A
authors.initials: A
authors.lastname: Ziranu
authors.forename: V
authors.initials: V
authors.lastname: Ciriello
mesh_terms: D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D019072:Antibiotic Prophylaxis / Q000379:methods*; D019644:Arthroplasty, Replacement, Hip / Q000009:adverse effects; D003094:Collagen; D006801:Humans; D011183:Postoperative Complications / Q000517:prevention & control; D016459:Prosthesis-Related Infections / Q000517:prevention & control*; D015503:Surgical Sponges
chemical_list: D000900:Anti-Bacterial Agents; D003094:Collagen