title: Osteonecrosis in genetic disorders.
abstract: The avascular necrosis of bone is characterized by an abnormality of tissue that can occur whenever a disease process causes major cell stress. Some evidence supports a role for genetic factors in some avascular necrosis suggesting that gene mutations could play a role in the pathogenesis of osteonecrosis. These genetic studies provide hope that tools for identifying high risk patients will be available in the future.
authors.affiliation: Department of Internal Medicine University of Florence, Florence, Italy.
authors.forename: Laura
authors.initials: L
authors.lastname: Masi
authors.forename: Alberto
authors.initials: A
authors.lastname: Falchetti
authors.forename: Maria Luisa
authors.initials: ML
authors.lastname: Brandi