title: Palladium-catalyzed intermolecular cyclocarbonylation of 2-iodoanilines with the Michael acceptor, diethyl ethoxycarbonylbutendienoate.
abstract: Palladium-catalyzed intermolecular cyclocarbonylation of 2-iodoanilines with diethyl ethoxycarbonylbutendienoate produces 2,3,3-triethoxycarbonyl-2,3-dihydro-4(1H)-quinolinone derivatives in moderate to good yields. This protocol involves Michael addition and subsequent carbonylation.
authors.affiliation: Centre for Catalysis Research and Innovation, Department of Chemistry, University of Ottawa, 10 Marie Curie, Ottawa, K1N 6N5, Canada.
authors.forename: Kazumi
authors.initials: K
authors.lastname: Okuro
authors.forename: Howard
authors.initials: H
authors.lastname: Alper
mesh_terms: D000814:Aniline Compounds / Q000737:chemistry*; D002087:Butyrates / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*; D015363:Quinolones / Q000138:chemical synthesis* / Q000737:chemistry*
chemical_list: C575098:2,3,3-triethoxycarbonyl-2,3-dihydro-4(1H)-quinolinone; C552400:2-iodobenzenamine; D000814:Aniline Compounds; D002087:Butyrates; D015363:Quinolones; D010165:Palladium