title: In vitro bactericidal activity against periodontopathic bacteria by electrolyzed ion-reduced water.
abstract: As typical periodontopathic bacteria, Porphyromonas gingivalis (P. gingivalis) and Aggregatibacter actinomycetemcomitans (A. actinomycetemcomitans) were exposed to electrolyzed ion-reduced water (ERI) and ERI containing 1% sodium carboxymethylcellulose (CMC-Na) (ERI-1% CMC-Na), and the time course of their bactericidal action was evaluated. More than 99% of each bacteria species were killed after exposure to each solution for 15 sec. In addition, 1% CMC-Na, which was added to prolong bactericidal action, did not affect the bactericidal action of ERI. Its bactericidal action was concentration-dependent. No viable P. gingivalis bacteria were observed at a concentration of 15% of the undiluted solution and no viable A. actinomycetemcomitans bacteria were observed at a concentration of 50%, indicating differences in the bactericidal action of ERI for the two bacteria species. These results suggest that ERI may be extremely useful in preventing and treating periodontal diseases.
authors.affiliation: Department of Pharmaceutical Sciences, Meiji Pharmaceutical University, Tokyo, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Okajima
authors.forename: M
authors.initials: M
authors.lastname: Kanzaki
authors.forename: Y
authors.initials: Y
authors.lastname: Ishibashi
authors.forename: Y
authors.initials: Y
authors.lastname: Wada
authors.forename: F
authors.initials: F
authors.lastname: Hino
authors.forename: Y
authors.initials: Y
authors.lastname: Kitahara
authors.forename: K
authors.initials: K
authors.lastname: Shimokawa
authors.forename: F
authors.initials: F
authors.lastname: Ishii