title: Occult left ventricular dysfunction diagnosed by myocardial performance index in patients with limb girdle muscle dystrophy: A case control study.
abstract: The myocardial performance index (MPI) was assessed in 30 patients with limb girdle muscle dystrophy (LGMD) with a normal left ventricular ejection fraction (greater than 50%), as well as in 30 age- and sex-matched healthy adults with a left ventricular ejection fraction greater than 50%. MPIs derived by pulsed-wave Doppler and tissue Doppler were also compared. The MPI was 0.37±0.09 in the LGMD patients and 0.29±0.09 in the control group (P=0.003). These data show that patients with LGMD have occult cardiac dysfunction as evidenced by a higher MPI than the controls. There was good agreement between the MPIs measured by pulsed-wave Doppler and tissue Doppler methods in these patients.
authors.affiliation: Department of Cardiology, Nizam's Institute of Medical Sciences, Hyderabad, India.
authors.forename: Rajashekar R
authors.initials: RR
authors.lastname: Gurrala
authors.forename: Venkata Mb
authors.initials: VM
authors.lastname: Alla
authors.forename: Wilbert S
authors.initials: WS
authors.lastname: Aronow
authors.forename: Jai S
authors.initials: JS
authors.lastname: Shankar
authors.forename: Meena K
authors.initials: MK
authors.lastname: Angamutta
authors.forename: Krishna
authors.initials: K
authors.lastname: Lanka
authors.forename: Sundaram
authors.initials: S
authors.lastname: Challa
authors.forename: Chandra K
authors.initials: CK
authors.lastname: Nair