title: The impact of allergic rhinitis on symptoms,  and  quality of life using the new criterion of ARIA severity classification.
abstract: Allergic rhinitis (AR) is a common disease with major socieconomic burden and a significant impact on quality of life.
  
  
  
  The objective of the study was to assess the impact of AR severity, using the modified ARIA (m-ARIA) severity criterion in order to discriminate among moderate and severe AR, in symptoms and quality of life assessed with the questionnaire ESPRINT-15.
  
  
  
  The specific quality of life questionnaire (ESPRINT-15) was applied in over thousand untreated RA patients. Severity was evaluated by the m-ARIA classification, which categorizes AR as mild, moderate, and severe. Nasal symptoms were evaluated by using categorized (none, low, middle, and high) Total Four Symptom Score (T4SS).
  
  
  
  Using the m-ARIA severity classification, significant differences in quality of life, both global score and specific domains, and categorized T4SS were found among the AR severity groups.
  
  
  
  Modified ARIA severity classification in mild, moderate, and severe allergic rhinitis clearly discriminates the impact of AR in all domains of quality of life and categorized symptom`s score.
authors.affiliation: Unitat d'Al.lèrgia, Servei de Pneumologia i Al.lèrgia Respiratòria, Hospital Clinic, Barcelona, Spain. Valero@clinic.ub.es
authors.forename: Antonio
authors.initials: A
authors.lastname: Valero
authors.forename: Rosa
authors.initials: R
authors.lastname: Muñoz-Cano
authors.forename: Joaquín
authors.initials: J
authors.lastname: Sastre
authors.forename: Ana M
authors.initials: AM
authors.lastname: Navarro
authors.forename: Enrique
authors.initials: E
authors.lastname: Martí-Guadaño
authors.forename: Ignacio
authors.initials: I
authors.lastname: Dávila
authors.forename: Alfonso
authors.initials: A
authors.lastname: del Cuvillo
authors.forename: Carlos
authors.initials: C
authors.lastname: Colás
authors.forename: Ignacio
authors.initials: I
authors.lastname: Antépara
authors.forename: Iñaki
authors.initials: I
authors.lastname: Izquierdo
authors.forename: Joaquim
authors.initials: J
authors.lastname: Mullol
mesh_terms: D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011788:Quality of Life; D012221:Rhinitis, Allergic, Perennial / Q000145:classification* / Q000175:diagnosis; D006255:Rhinitis, Allergic, Seasonal / Q000145:classification* / Q000175:diagnosis; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires