title: [Post-infectious irritable bowel syndrome].
abstract: BACKGROUND
  Post-infectious irritable bowel syndrome (PI-IBS) is a disorder wherein symptoms of IBS begin after an episode of acute gastroenteritis.
  
  
  OBJECTIVE
  To determine epidemiology, clinical features and prognosis of PI-IBS and to precise its physiopathology and treatment.
  
  
  METHODS
  Literature review.
  
  
  RESULTS
  Published studies have reported an incidence of PI-IBS ranging from 4 to 32 % with a mean of 10 %. Bacterial infections are the most responsible agents. Risk factors for PI-IBS include patient's demographics, psychological disorders and the severity of enteric illness. The most common symptoms are those of diarrheapredominant IBS. The mechanisms underlying PI-IBS include especially changes in intestinal permeability and persistent mucosal inflammatory process. In fact, there is increase in lymphocytic, mast and enterochromaffin cells in the gut mucosa. Furthermore, increased inflammatory cytokines have been demonstrated. Treatment of PIIBS is similar to that idiopathic IBS.
  
  
  CONCLUSIONS
  PI-IBS is a novel clinic entity that suggests a novel approaches to IBS.
authors.affiliation: Service de Gastro-entérologie A. Hôpital la Rabta, Tunis.
authors.forename: Meriem
authors.initials: M
authors.lastname: Serghini
authors.forename: Sami
authors.initials: S
authors.lastname: Karoui
authors.forename: Jalel
authors.initials: J
authors.lastname: Boubaker
authors.forename: Azza
authors.initials: A
authors.lastname: Filali
mesh_terms: D001424:Bacterial Infections / Q000150:complications* / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy; D005759:Gastroenteritis / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology; D006801:Humans; D006967:Hypersensitivity / Q000378:metabolism / Q000503:physiopathology; D016867:Immunocompromised Host / Q000502:physiology; D007413:Intestinal Mucosa / Q000276:immunology / Q000378:metabolism / Q000473:pathology / Q000503:physiopathology; D043183:Irritable Bowel Syndrome / Q000175:diagnosis* / Q000453:epidemiology / Q000209:etiology* / Q000628:therapy; D008954:Models, Biological; D010539:Permeability; D011379:Prognosis; D012307:Risk Factors