title: A case of Takayasu arteritis with repeated coronary artery restenosis after drug-eluting stent implantation successfully treated with a combination of steroids.
abstract: A 52-year-old woman with Takayasu arteritis developed acute coronary syndrome and received percutaneous coronary intervention (PCI). The patient experienced restenosis three times even with drug-eluting stent (DES) implantation. We started steroid administration after the fourth PCI to reduce inflammation due to autoimmunity. With DES and a steroid combination, the patient remained free of chest pain, and a follow-up angiography demonstrated good patency of the stent site. Since in-stent restenosis may result from a complicated combination of neointimal proliferation and autoimmune mechanisms, physicians should consider a combination of DES and a steroid for the treatment of coronary artery disease in Takayasu arteritis.
authors.affiliation: Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Japan.
authors.forename: Katsuaki
authors.initials: K
authors.lastname: Yokota
authors.forename: Masahisa
authors.initials: M
authors.lastname: Shimpo
authors.forename: Tomohiko
authors.initials: T
authors.lastname: Iwata
authors.forename: Masahiro
authors.initials: M
authors.lastname: Hirose
authors.forename: Tomokazu
authors.initials: T
authors.lastname: Ikemoto
authors.forename: Ken-ichi
authors.initials: K
authors.lastname: Ohya
authors.forename: Takaaki
authors.initials: T
authors.lastname: Katsuki
authors.forename: Kazuyuki
authors.initials: K
authors.lastname: Shimada
authors.forename: Kazuomi
authors.initials: K
authors.lastname: Kario
mesh_terms: D015906:Angioplasty, Balloon, Coronary; D017023:Coronary Angiography; D023903:Coronary Restenosis / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000628:therapy*; D054855:Drug-Eluting Stents; D005260:Female; D006801:Humans; D008875:Middle Aged; D058426:Neointima / Q000000981:diagnostic imaging; D020123:Sirolimus / Q000008:administration & dosage; D013256:Steroids / Q000008:administration & dosage / Q000627:therapeutic use*; D013625:Takayasu Arteritis / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000628:therapy*; D014057:Tomography, X-Ray Computed
chemical_list: D013256:Steroids; D020123:Sirolimus