title: Reversibility of electric-field-induced mechanical changes in soft tissues.
abstract: Recently, ultrasound has been used to study the physiological-level electric-field-induced mechanical changes (EIMC) in general soft biological tissues. Here, we present the experimental results on the dependence of EIMC on the polarity of the applied electric field. We applied an ac voltage source to heart tissues and monitored the amplitude changes and time shifting of the ultrasound echoes. The shifting of the echoes was decomposed into a trend component and a fluctuation (feature) component. The changes in amplitude and the fluctuation component of the time shift, but not the trend component of the time shift, can be mostly reversed by reversing the polarity of the applied voltage. The polarity-dependence study reveals two different mechanisms underlying EIMC.
authors.forename: Ozkan
authors.initials: O
authors.lastname: Doganay
authors.forename: Yuan
authors.initials: Y
authors.lastname: Xu
mesh_terms: D000818:Animals; D055119:Elastic Modulus / Q000502:physiology / Q000528:radiation effects; D004574:Electromagnetic Fields; D006321:Heart / Q000502:physiology* / Q000528:radiation effects*; D066298:In Vitro Techniques; D011829:Radiation Dosage; D033081:Shear Strength / Q000502:physiology / Q000528:radiation effects; D013314:Stress, Mechanical; D013552:Swine; D014783:Viscosity / Q000528:radiation effects