title: Association of parathyroid pathology with well-differentiated thyroid carcinoma.
abstract: OBJECTIVE
  The objective was to evaluate the association of well-differentiated thyroid carcinoma and parathyroid pathology.
  
  
  METHODS
  The medical records of 14 patients with concomitant pathologies were retrospectively reviewed.
  
  
  RESULTS
  Parathyroidectomies (1.3%) and thyroidectomies (3.5%) performed for well-differentiated thyroid carcinoma resulted in the diagnosis of concomitant pathologies. Five patients had a primary hyperparathyroidism (PHPT) and nine were operated for thyroidectomy with intraoperative finding of an enlarged parathyroid gland. Patients (64%) were normocalcemic preoperatively. Thirteen had papillary carcinoma. Fifty percent of patients had multiple foci of papillary microcarcinoma. Twenty-nine percent of patients had parathyroid hyperplasia. All patients with preoperative hypercalcemia normalized their serum calcium. During follow-up, thyroglobuline, calcium serum values and cervical ultrasound showed no evidence of recurrence of the diseases.
  
  
  CONCLUSIONS
  These observations stress the importance of pre and intraoperative evaluation to detect overt thyroid and parathyroid pathology before performing a parathyroidectomy for hyperparathyroidism or a thyroidectomy for a well-differentiated thyroid carcinoma.
authors.affiliation: Saint-Joseph university, faculty of medicine, Hôtel-Dieu de France hospital, department of pathology, Beirut, Lebanon.
authors.forename: Claude
authors.initials: C
authors.lastname: Ghorra
authors.forename: Habib
authors.initials: H
authors.lastname: Rizk
authors.forename: Ralph
authors.initials: R
authors.lastname: Abi Hachem
authors.forename: Jenny
authors.initials: J
authors.lastname: Tannoury
authors.forename: Bassam
authors.initials: B
authors.lastname: Abboud
mesh_terms: D000328:Adult; D000368:Aged; D002118:Calcium / Q000097:blood*; D005260:Female; D006801:Humans; D006961:Hyperparathyroidism / Q000150:complications / Q000473:pathology* / Q000601:surgery; D059012:Lost to Follow-Up; D008297:Male; D008875:Middle Aged; D010280:Parathyroid Glands / Q000473:pathology* / Q000601:surgery; D010281:Parathyroid Hormone / Q000097:blood*; D010282:Parathyroid Neoplasms / Q000150:complications / Q000473:pathology* / Q000601:surgery; D012189:Retrospective Studies; D013961:Thyroid Gland / Q000473:pathology* / Q000601:surgery; D013964:Thyroid Neoplasms / Q000150:complications / Q000473:pathology* / Q000601:surgery; D013965:Thyroidectomy
chemical_list: D010281:Parathyroid Hormone; D002118:Calcium