title: Ti-catalyzed homolytic opening of ozonides: a sustainable C-C bond-forming reaction.
abstract: The unprecedented homolytic opening of ozonides promoted and catalyzed by titanocene(III) is reported. This novel reaction proceeds at room temperature under neutral, mild conditions compatible with many functional groups and provides carbon radicals suitable to form C-C bonds via both homocoupling and cross-coupling processes. The procedure has been advantageously exploited for the straightforward synthesis of the natural product brittonin A.
authors.affiliation: Department of Organic Chemistry, Faculty of Sciences, University of Granada, 18071 Granada, Spain. a.rosales.martinez@gmail.com
authors.forename: Antonio
authors.initials: A
authors.lastname: Rosales
authors.forename: Juan
authors.initials: J
authors.lastname: Muñoz-Bascón
authors.forename: Cristóbal
authors.initials: C
authors.lastname: López-Sánchez
authors.forename: Míriam
authors.initials: M
authors.lastname: Álvarez-Corral
authors.forename: Manuel
authors.initials: M
authors.lastname: Muñoz-Dorado
authors.forename: Ignacio
authors.initials: I
authors.lastname: Rodríguez-García
authors.forename: J Enrique
authors.initials: JE
authors.lastname: Oltra