title: [Meta-analysis of the effectiveness of plasma exchange in treatment of severe and acute organophosphate  poisoning].
abstract: OBJECTIVE
  To discuss the effectiveness of severe and acute organophosphate poisoning (AOPP) treated with plasma exchange in China.
  
  
  METHODS
  Researches about effectiveness of severe AOPP treated with plasma exchange were analyzed by Review Manager 4.2 and fixed effect model of meta-analysis method were used.
  
  
  RESULTS
  Six trials including 433 patients were identified. Treatment group including 211 patients adopted traditional physician therapy plus plasma exchange, and control group including 222 patients received physician therapy only. The case-fatality rate of the treatment group was lower than the control one [RR=0.30, 95%CI (0.19-0.49), P<0.01].
  
  
  CONCLUSIONS
  Plasma exchange can improve the cure rate of severe AOPP.
authors.affiliation: Department of Occupational Disease, Huashan Hospital, Fudan University, Shanghai 200040, China.
authors.forename: Hao-min
authors.initials: HM
authors.lastname: Qiu
authors.forename: Shu-cong
authors.initials: SC
authors.lastname: Zheng
authors.forename: Wei-guo
authors.initials: WG
authors.lastname: Wan
authors.forename: He-jian
authors.initials: HJ
authors.lastname: Zou
mesh_terms: D006801:Humans; D062025:Organophosphate Poisoning / Q000628:therapy*; D010575:Pesticides / Q000506:poisoning*; D010956:Plasmapheresis
chemical_list: D010575:Pesticides