title: HLA and skin cancer.
abstract: Skin cancer - melanoma and non melanoma - are common neoplasm with rising incidence over the last decades. It is an important public health problem. Its pathogenesis is not completely understood and the same happens with the genetic factors involved. The genes that encode the HLA are associated with some tumors and they may be responsible for one of the mechanisms that take part in the development of the before mentioned cancers. We have reviewed the literature on the subject of HLA antigens, melanoma and non melanoma skin cancer.
authors.affiliation: Service of Dermatology, Federal University of Health Sciences of Porto Alegre, RS, Brazil.
authors.forename: Renan Rangel
authors.initials: RR
authors.lastname: Bonamigo
authors.forename: André Vicente Esteves de
authors.initials: AV
authors.lastname: Carvalho
authors.forename: Vanessa Raquel Zaleski
authors.initials: VR
authors.lastname: Sebastiani
authors.forename: Cristina Martino da
authors.initials: CM
authors.lastname: Silva
authors.forename: Angela Caroline de Zorzi
authors.initials: AC
authors.lastname: Pinto
mesh_terms: D002280:Basal Cell Carcinoma / Q000235:genetics* / Q000276:immunology; D002294:Carcinoma, Squamous Cell / Q000235:genetics* / Q000276:immunology; D006680:HLA Antigens / Q000235:genetics*; D006801:Humans; D008545:Melanoma / Q000235:genetics* / Q000276:immunology; D012307:Risk Factors; D012878:Skin Neoplasms / Q000235:genetics* / Q000276:immunology
chemical_list: D006680:HLA Antigens