title: The effects of a multifunctional oligomer and its incorporation strategies on the gene delivery efficiency of poly(L-lysine).
abstract: A novel multifunctional oligomer is synthesized and incorporated to enhance the gene delivery efficiency of PLL via non-electrostatic assembly and covalent grafting strategies. The improvement of the gene delivery efficiency is dependent on the gene carrying complex properties, and the properties are dependent on the oligomer incorporation strategy.
authors.affiliation: Key Laboratory of Functional Polymer Materials, Ministry of Education, Institute of Polymer Chemistry, College of Chemistry, Nankai University, Weijin Road, No. 94, Tianjin, 300071, China.
authors.forename: Dezhong
authors.initials: D
authors.lastname: Zhou
authors.forename: Congxin
authors.initials: C
authors.lastname: Li
authors.forename: Yuling
authors.initials: Y
authors.lastname: Hu
authors.forename: Hao
authors.initials: H
authors.lastname: Zhou
authors.forename: Jiatong
authors.initials: J
authors.lastname: Chen
authors.forename: Zhengpu
authors.initials: Z
authors.lastname: Zhang
authors.forename: Tianying
authors.initials: T
authors.lastname: Guo
mesh_terms: D000180:Acrylic Resins / Q000138:chemical synthesis / Q000737:chemistry*; D018014:Gene Transfer Techniques; D006367:HeLa Cells; D006639:Histidine / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry; D006801:Humans; D007785:Lactose / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry; D010957:Plasmids / Q000737:chemistry / Q000378:metabolism; D011107:Polylysine / Q000737:chemistry*; D055672:Static Electricity
chemical_list: D000180:Acrylic Resins; D011107:Polylysine; D006639:Histidine; D007785:Lactose