title: [Pregnancy and acute pulmonary embolism: a case report].
abstract: We describe the case of a 37-year-old pregnant woman who presented at 29 weeks of gestation with syncope and shortness of breath caused by pulmonary embolism. Due to persistent hypotension thrombolytic therapy with tenecteplase was administered and the clinical and hemodynamic response was excellent, with no maternal or fetal hemorrhagic complications. The clinical presentation of pulmonary embolism is sometimes camouflaged by the physiological changes that occur in pregnancy and diagnosis is often delayed by reluctance to expose the fetus to ionizing radiation. Systemic thrombolysis is considered a high-risk treatment in pregnancy and very few women have received it. However the complication rates of thrombolytic therapy are acceptable in the light of the underlying disease.
authors.affiliation: Serviço de Cardiologia, Centro Hospitalar Tondela Viseu, E.P.E., Viseu, Portugal. luisferreirasantos@gmail.com
authors.forename: Luís Ferreira
authors.initials: LF
authors.lastname: dos Santos
authors.forename: Cláudia
authors.initials: C
authors.lastname: Andrade
authors.forename: Bruno
authors.initials: B
authors.lastname: Rodrigues
authors.forename: Davide
authors.initials: D
authors.lastname: Moreira
authors.forename: Anne
authors.initials: A
authors.lastname: Delgado
authors.forename: Pedro
authors.initials: P
authors.lastname: Manso
authors.forename: António
authors.initials: A
authors.lastname: Pipa
authors.forename: Pedro
authors.initials: P
authors.lastname: Gama
authors.forename: Luís
authors.initials: L
authors.lastname: Nunes
authors.forename: Odete
authors.initials: O
authors.lastname: Dionísio
authors.forename: Nuno
authors.initials: N
authors.lastname: Ribeiro
authors.forename: Oliveira
authors.initials: O
authors.lastname: Santos
mesh_terms: D000208:Acute Disease; D000328:Adult; D005260:Female; D006801:Humans; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000175:diagnosis / Q000188:drug therapy; D011655:Pulmonary Embolism / Q000175:diagnosis / Q000188:drug therapy