title: Longer FVIII: the 4th generation.
abstract: In this issue of Blood, Powell and colleagues present the first human data after the infusion of a new recombinant factor VIII (FVIII) product that when fused with the Fc fragment of IgG1 results in significantly prolonged half-life in the circulation.
authors.affiliation: University of Sheffield.
authors.forename: Michael
authors.initials: M
authors.lastname: Makris
mesh_terms: D005169:Factor VIII / Q000493:pharmacokinetics* / Q000627:therapeutic use*; D006467:Hemophilia A / Q000188:drug therapy*; D006801:Humans; D008297:Male; D011961:Receptors, Fc / Q000627:therapeutic use*
chemical_list: D011961:Receptors, Fc; D005169:Factor VIII