title: Oral squamous cell carcinoma in a Crohn's disease patient taking azathioprine: case report and review of the literature.
abstract: Thiopurines are widely used for remission maintenance and post-operative recurrence prevention in Crohn's disease. The increased risk of cancer in transplant recipients on azathioprine is well recognized and there are concerns that this may also be true for inflammatory bowel disease patients. We report a case of a 33-year-old Caucasian woman with Crohn's disease treated with azathioprine for 9 years who developed an ulcerated lesion at the right superior retromolar trigone. Biopsy specimen revealed a squamous cell carcinoma.
authors.forename: Filipe
authors.initials: F
authors.lastname: Vilas-Boas
authors.forename: Fernando
authors.initials: F
authors.lastname: Magro
authors.forename: Rui
authors.initials: R
authors.lastname: Balhau
authors.forename: José M
authors.initials: JM
authors.lastname: Lopes
authors.forename: Francisco
authors.initials: F
authors.lastname: Beça
authors.forename: Catarina
authors.initials: C
authors.lastname: Eloy
authors.forename: Susana
authors.initials: S
authors.lastname: Lopes
authors.forename: Guilherme
authors.initials: G
authors.lastname: Macedo
mesh_terms: D000328:Adult; D001379:Azathioprine / Q000009:adverse effects*; D002294:Carcinoma, Squamous Cell / Q000139:chemically induced*; D003424:Crohn Disease / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects*; D009062:Mouth Neoplasms / Q000139:chemically induced*
chemical_list: D007166:Immunosuppressive Agents; D001379:Azathioprine