title: Comparative study of the iron cores in human liver ferritin, its pharmaceutical models and ferritin in chicken liver and spleen tissues using Mössbauer spectroscopy with a high velocity resolution.
abstract: Application of Mössbauer spectroscopy with a high velocity resolution (4096 channels) for comparative analysis of iron cores in a human liver ferritin and its pharmaceutically important models Imferon, Maltofer(®) and Ferrum Lek as well as in iron storage proteins in chicken liver and spleen tissues allowed to reveal small variations in the (57)Fe hyperfine parameters related to differences in the iron core structure. Moreover, it was shown that the best fit of Mössbauer spectra of these samples required different number of components. The latter may indicate that the real iron core structure is more complex than that following from a simple core-shell model. The effect of different living conditions and age on the iron core in chicken liver was also considered.
authors.affiliation: Department of Physical Techniques and Devices for Quality Control, Institute of Physics and Technology, Ural Federal University, Ekaterinburg 620002, Russian Federation.
authors.forename: I V
authors.initials: IV
authors.lastname: Alenkina
authors.forename: M I
authors.initials: MI
authors.lastname: Oshtrakh
authors.forename: Yu V
authors.initials: YV
authors.lastname: Klepova
authors.forename: S M
authors.initials: SM
authors.lastname: Dubiel
authors.forename: N V
authors.initials: NV
authors.lastname: Sadovnikov
authors.forename: V A
authors.initials: VA
authors.lastname: Semionkin
mesh_terms: D000818:Animals; D002645:Chickens; D005293:Ferritins / Q000032:analysis* / Q000737:chemistry*; D005612:Freeze Drying; D006801:Humans; D007501:Iron / Q000032:analysis* / Q000737:chemistry; D007505:Iron-Dextran Complex / Q000032:analysis / Q000737:chemistry*; D008099:Liver / Q000378:metabolism*; D008956:Models, Chemical; D009942:Organometallic Compounds / Q000032:analysis / Q000737:chemistry*; D011134:Polysaccharides / Q000032:analysis / Q000737:chemistry*; D015204:Spectroscopy, Mossbauer / Q000379:methods*; D013154:Spleen / Q000378:metabolism*; D013696:Temperature
chemical_list: D009942:Organometallic Compounds; D011134:Polysaccharides; C009766:ferrum lek; D007505:Iron-Dextran Complex; D005293:Ferritins; D007501:Iron