title: Effect of subcutaneous selenium injection and supplementary selenium source on blood selenium and glutathione peroxidase in feedlot heifers.
abstract: This study measured the effect on glutathione peroxidase (GSH-Px) and selenium (Se) in whole blood and plasma associated with subcutaneous Se injections in beef heifers fed organic or inorganic Se. Heifers (n = 120) were randomly divided into 2 groups, 1 of which received subcutaneous Se injections. Both groups were given the same total mixed ration with 3 mg of organic or inorganic Se daily. Until week 2, heifers that had received Se injections showed higher concentrations of plasma Se and GSH-Px and whole blood Se (P < 0.001) than those having had no injections. Concentrations of plasma Se and GSH-Px were higher in the group receiving organic Se than the group receiving inorganic Se. Whole blood GSH-Px concentrations increased significantly (P < 0.001) throughout a 12-week period but were not affected by Se source. Combination of Se injections and supplementation could help maintain normal Se and GSH-Px blood status in beef heifers during the first few weeks in the feedlot.
authors.affiliation: Département de Biomédecine Vétérinaire, Faculté de médecine vétérinaire, 3200, Sicotte CP 5000, Saint-Hyacinthe, Quebec J2S 7C6. younes.chorfi@umontreal.ca
authors.forename: Younes
authors.initials: Y
authors.lastname: Chorfi
authors.forename: Vincent
authors.initials: V
authors.lastname: Girard
authors.forename: Alain
authors.initials: A
authors.lastname: Fournier
authors.forename: Yvon
authors.initials: Y
authors.lastname: Couture
mesh_terms: D000821:Animal Feed; D000824:Animal Nutritional Physiological Phenomena; D000818:Animals; D001682:Biological Availability; D002417:Cattle / Q000097:blood*; D004912:Erythrocytes / Q000737:chemistry; D005260:Female; D005527:Food, Fortified; D005979:Glutathione Peroxidase / Q000378:metabolism*; D007279:Injections, Subcutaneous / Q000662:veterinary; D011897:Random Allocation; D012643:Selenium / Q000008:administration & dosage* / Q000097:blood* / Q000493:pharmacokinetics
chemical_list: D005979:Glutathione Peroxidase; D012643:Selenium