title: [Are genetic tests useful for cardiovascular prevention?].
abstract: Recent progresses in genetics have opened new avenues to further our understanding of the pathophysiological mechanisms underlying cardiovascular disease, raising, new expectations in the field of personalized medicine. Genetic tests may have a high predictive value for rare monogenic diseases. The situation is very different for common polygenic diseases, such as myocardial infarction, type 2 diabetes or stroke. The results from recent genome-wide association studies have provided useful information for research, but have not yet been proven to be clinically useful. It is therefore currently not recommended to conducted genetic testing to guide cardiovascular prevention neither in clinical nor in public health settings.
authors.affiliation: Unité de prévention communautaire, Institut de médecine sociale et préventive, CHUV, 1011 Lausanne. Murielle.Bochud@chuv.ch
authors.forename: Murielle
authors.initials: M
authors.lastname: Bochud
authors.forename: Florence
authors.initials: F
authors.lastname: Fellmann
authors.forename: Idris
authors.initials: I
authors.lastname: Guessous
mesh_terms: D002318:Cardiovascular Diseases / Q000175:diagnosis* / Q000235:genetics / Q000517:prevention & control*; D018890:Chemoprevention; D005820:Genetic Testing; D006801:Humans; D012307:Risk Factors