title: Evaluation of clinical aspects and quality of life as risk factors for depression in patients with epilepsy.
abstract: The purpose of this study was to investigate clinical aspects and quality of life (QOL) as risk factors for depression in patients with epilepsy. One hundred and forty outpatients with a diagnosis of epilepsy who were attending our epilepsy center participated. Patients anonymously filled out a questionnaire with clinical data related to epilepsy. Depression level was evaluated by the Hamilton Depression Rating Scale-17 (HAMD-17), and quality of life was evaluated by the Quality of Life in Epilepsy-31 (QOLIE-31). Thirty-six patients with epilepsy suffered from depression (25.7%). Complex partial seizures (OR=0.112) and number of seizure types (OR=3.773) were found to be clinical risk factors for depression. Low scores for seizure worry (OR=0.947) and social function (OR=0.947) on the QOLIE-31 increased the probability of depression in patients with epilepsy.
authors.affiliation: Institute of Neurology, Huashan Hospital, Fudan University, Shanghai, China.
authors.forename: Ting
authors.initials: T
authors.lastname: Zhao
authors.forename: Ming-Yue
authors.initials: MY
authors.lastname: Sun
authors.forename: Pei-Min
authors.initials: PM
authors.lastname: Yu
authors.forename: Guo-Xing
authors.initials: GX
authors.lastname: Zhu
authors.forename: Xing-Hua
authors.initials: XH
authors.lastname: Tang
authors.forename: Yun-Bo
authors.initials: YB
authors.lastname: Shi
authors.forename: Zhen
authors.initials: Z
authors.lastname: Hong
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D003863:Depression / Q000150:complications* / Q000175:diagnosis / Q000209:etiology*; D004827:Epilepsy / Q000150:complications* / Q000175:diagnosis / Q000523:psychology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011788:Quality of Life; D012307:Risk Factors; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires; D055815:Young Adult