title: Acute ST-elevation myocardial infarction 6 years following a sirolimus-eluting stent secondary to complete stent fracture.
abstract: With increasing coronary interventions, coronary stent fracture following implantation of drug-eluting stents is being commonly recognized. Though isolated strut fractures are often only incidental findings, more severe forms of stent fracture with complete transection have adverse clinical outcomes. Most such cases are reported within several months following the index angioplasty. We report an unusual presentation of late stent fracture following a sirolimus-eluting stent, presenting with acute myocardial infarction 6 years after the initial stent implantation. The various mechanisms underlying fracture of drug-eluting stents are reviewed. Because no known mechanisms were noted in our case, unknown factors may also play a role in the genesis of stent fracture. Clinicians need to be aware that such complications may present rarely, extremely late after the index procedure as an acute myocardial infarction.
authors.affiliation: Dept. Of Cardiology, Sanjay Gandhi PGIMS, Lucknow 226014, India.
authors.forename: Roopali
authors.initials: R
authors.lastname: Khanna
authors.forename: Aditya
authors.initials: A
authors.lastname: Kapoor
authors.forename: Nakul
authors.initials: N
authors.lastname: Sinha
mesh_terms: D015906:Angioplasty, Balloon, Coronary / Q000295:instrumentation* / Q000379:methods; D001026:Coronary Artery Bypass; D003324:Coronary Artery Disease / Q000628:therapy; D054855:Drug-Eluting Stents / Q000009:adverse effects*; D004562:Electrocardiography; D004868:Equipment Failure; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000175:diagnosis* / Q000209:etiology* / Q000628:therapy; D020123:Sirolimus; D013997:Time Factors
chemical_list: D020123:Sirolimus