title: [Calcium supplementation uncovering lactose intolerance - a case report].
abstract: A 44 yr-old female with osteoporosis had no relevant gastrointestinal symptoms and did not avoid any specific food. However, after prescription of a lactose-rich calcium supplementation, clinical symptoms suspicious for lactose intolerance occurred, which were thereafter confirmed by a lactose tolerance test. Lactose intolerance may present with only slight or subtle symptoms. Drugs containing lactose may induce or increase gastrointestinal symptoms in patients with lactose intolerance. In case of gastrointestinal symptoms occurring after the initiation of drugs containing lactose, the possibility of lactose intolerance should be considered and tested by lactose tolerance test or genetic testing for the LCT (-13910) polymorphism. Due to the prevalence of about 15-25% lactose intolerance in the Austrian population, lactose free drugs should be prescribed as widely as possible.
authors.affiliation: 1. Medizinische Abteilung und Ludwig Boltzmann-Institut für Osteologie, Hanusch-Krankenhaus, Wien, Austria.
authors.forename: Eva
authors.initials: E
authors.lastname: Trifina
authors.forename: Dietmar
authors.initials: D
authors.lastname: Geissler
authors.forename: Elisabeth
authors.initials: E
authors.lastname: Zwettler
authors.forename: Klaus
authors.initials: K
authors.lastname: Klaushofer
authors.forename: Peter
authors.initials: P
authors.lastname: Mikosch
mesh_terms: D015746:Abdominal Pain / Q000209:etiology*; D015502:Absorptiometry, Photon; D000328:Adult; D001317:Austria; D002119:Calcium Carbonate / Q000008:administration & dosage* / Q000009:adverse effects*; D003967:Diarrhea / Q000209:etiology*; D005079:Excipients / Q000009:adverse effects*; D005260:Female; D005820:Genetic Testing; D006801:Humans; D007785:Lactose / Q000008:administration & dosage* / Q000009:adverse effects*; D007787:Lactose Intolerance / Q000175:diagnosis* / Q000235:genetics; D010024:Osteoporosis / Q000175:diagnosis / Q000188:drug therapy*; D011110:Polymorphism, Genetic / Q000235:genetics
chemical_list: D005079:Excipients; D002119:Calcium Carbonate; D007785:Lactose