title: Medium term endoscopic assessment of the surgical outcome following laryngeal saccule resection in brachycephalic dogs.
abstract: Laryngeal saccule eversion has been widely reported as an important component of brachycephalic airway obstructive syndrome (BAOS). The authors hypothesised that saccules affected by acute histological changes in patients showing marked improvement following palate and nares surgery might spontaneously return to normal; moreover, spontaneous resolution of the eversion in patients with fibrotic saccules and/or without clinical improvement following BAOS surgery might be impossible and, on the contrary, the persistence of turbulent airflow and associated ongoing inflammation might lead to aberrant tissue proliferation after resection. In order to demonstrate our hypotheses, the authors decided to perform a unilateral sacculectomy and to postpone and assess the need for the execution of the contralateral saccule resection according to the findings of a second-look laryngoscopy. Ten dogs were enrolled. None of the saccules left in situ underwent spontaneous resolution of the eversion. In one dog, after sacculectomy, proliferation of a soft tissue lesion endoscopically similar to a newly formed saccule occurred. The results of the present study suggest that spontaneous resolution of saccule eversion is uncommon, even after the correction of the primary abnormalities (palate, nares). Resection of the saccules can relieve ventral rima glottidis obstruction; however, secondary intention healing might occasionally result in the recurrence of the obstruction.
authors.affiliation: Hospital for Small Animals, Royal (Dick) School of Veterinary Studies, The University of Edinburgh, Easter Bush Veterinary Centre, Roslin, Midlothian EH25 9RG, UK.
authors.forename: M
authors.initials: M
authors.lastname: Cantatore
authors.forename: M
authors.initials: M
authors.lastname: Gobbetti
authors.forename: S
authors.initials: S
authors.lastname: Romussi
authors.forename: G
authors.initials: G
authors.lastname: Brambilla
authors.forename: C
authors.initials: C
authors.lastname: Giudice
authors.forename: V
authors.initials: V
authors.lastname: Grieco
authors.forename: D
authors.initials: D
authors.lastname: Stefanello
mesh_terms: D000402:Airway Obstruction / Q000235:genetics / Q000601:surgery / Q000662:veterinary*; D000818:Animals; D001947:Breeding; D003251:Constriction, Pathologic / Q000235:genetics / Q000601:surgery / Q000662:veterinary; D004283:Dog Diseases / Q000235:genetics / Q000601:surgery*; D004285:Dogs; D004724:Endoscopy / Q000379:methods / Q000662:veterinary; D005260:Female; D007818:Laryngeal Diseases / Q000601:surgery / Q000662:veterinary*; D008297:Male; D009296:Nasal Cavity / Q000002:abnormalities* / Q000601:surgery*; D010160:Palate, Soft / Q000002:abnormalities / Q000601:surgery; D012008:Recurrence; D016896:Treatment Outcome