title: Willingness to accept HIV pre-exposure prophylaxis among Chinese men who have sex with men.
abstract: OBJECTIVE
  We investigated the awareness and acceptability of pre-exposure prophylaxis (PrEP) among men who have sex with men (MSM) and potential predicting factors.
  
  
  METHODS
  This study was conducted among MSM in Beijing, China. Study participants, randomly selected from an MSM cohort, completed a structured questionnaire, and provided their blood samples to test for HIV infection and syphilis. Univariate logistic regression analyses were performed to evaluate the factors associated with willingness to accept (WTA) PrEP. Factors independently associated with willingness to accept were identified by entering variables into stepwise logistic regression analysis.
  
  
  RESULTS
  A total of 152 MSM completed the survey; 11.2% had ever heard of PrEP and 67.8% were willing to accept it. Univariate analysis showed that age, years of education, consistent condom use in the past 6 months, heterosexual behavior in the past 6 months, having ever heard of PrEP and the side effects of antiretroviral drugs, and worry about antiretroviral drugs cost were significantly associated with willingness to accept PrEP. In the multivariate logistic regression model, only consistent condom use in the past 6 months (odds ratio [OR]: 0.31; 95% confidence interval [CI]: 0.13-0.70) and having ever heard of the side effects of antiretroviral drugs (OR: 0.30; 95% CI: 0.14-0.67) were independently associated with willingness to accept PrEP.
  
  
  CONCLUSIONS
  The awareness of PrEP in the MSM population was low. Sexual behavioral characteristics and knowledge about ART drugs may have effects on willingness to accept PrEP. Comprehensive prevention strategies should be recommended in the MSM community.
authors.affiliation: Institute of Pathogen Biology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
authors.forename: Feng
authors.initials: F
authors.lastname: Zhou
authors.forename: Lei
authors.initials: L
authors.lastname: Gao
authors.forename: Shuming
authors.initials: S
authors.lastname: Li
authors.forename: Dongliang
authors.initials: D
authors.lastname: Li
authors.forename: Lifen
authors.initials: L
authors.lastname: Zhang
authors.forename: Wensheng
authors.initials: W
authors.lastname: Fan
authors.forename: Xueying
authors.initials: X
authors.lastname: Yang
authors.forename: Mingrun
authors.initials: M
authors.lastname: Yu
authors.forename: Dong
authors.initials: D
authors.lastname: Xiao
authors.forename: Li
authors.initials: L
authors.lastname: Yan
authors.forename: Zheng
authors.initials: Z
authors.lastname: Zhang
authors.forename: Wei
authors.initials: W
authors.lastname: Shi
authors.forename: Fengji
authors.initials: F
authors.lastname: Luo
authors.forename: Yuhua
authors.initials: Y
authors.lastname: Ruan
authors.forename: Qi
authors.initials: Q
authors.lastname: Jin
mesh_terms: D000293:Adolescent; D000328:Adult; D044966:Anti-Retroviral Agents / Q000627:therapeutic use*; D044466:Asian People / Q000706:statistics & numerical data; D002681:China / Q000453:epidemiology; D015331:Cohort Studies; D006678:HIV / Q000187:drug effects*; D015658:HIV Infections / Q000208:ethnology / Q000517:prevention & control* / Q000821:virology; D007722:Health Knowledge, Attitudes, Practice; D018451:Homosexuality, Male / Q000523:psychology* / Q000706:statistics & numerical data; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D018570:Risk Assessment / Q000706:statistics & numerical data; D012307:Risk Factors; D011795:Surveys and Questionnaires; D055815:Young Adult
chemical_list: D044966:Anti-Retroviral Agents