title: Robustness in crossover regulation during meiosis.
abstract: Meiotic recombination produces physical linkages between homologous chromosomes that enable their segregation to opposite poles during meiosis I. In the absence of recombination, chromosomes mis-segregate, resulting in aneuploidy associated with severe birth defects. A recent study provides exciting insights into how recombination is fine-tuned to enforce a robust meiotic program.
authors.forename: Chitra V
authors.initials: CV
authors.lastname: Kotwaliwale
mesh_terms: D000818:Animals; D006706:Homeostasis; D008297:Male; D008540:Meiosis / Q000235:genetics*; D011995:Recombination, Genetic / Q000235:genetics*