title: Hybrid metal/organo relay catalysis enables enynes to be latent dienes for asymmetric Diels-Alder reaction.
abstract: The hybrid Au(I)/Brønsted acid binary catalyst system enables enynes to serve as latent 1,3-silyloxydienes capable of participating in the first cascade hydrosiloxylation of an enynyl silanol/asymmetric Diels-Alder reaction. A variety of polycyclic compounds bearing multistereogenic centers were obtained in high yields and excellent enantioselectivities from the relay catalytic cascade reaction between (2-(but-3-en-1-ynyl)phenyl) silanols and quinones catalyzed by the combined achiral gold complex and chiral N-triflyl phosphoramide.
authors.affiliation: Hefei National Laboratory for Physical Sciences at the Microscale and Department of Chemistry, University of Science and Technology of China, Hefei, 230026, China.
authors.forename: Zhi-Yong
authors.initials: ZY
authors.lastname: Han
authors.forename: Dian-Feng
authors.initials: DF
authors.lastname: Chen
authors.forename: Ya-Yi
authors.initials: YY
authors.lastname: Wang
authors.forename: Rui
authors.initials: R
authors.lastname: Guo
authors.forename: Pu-Sheng
authors.initials: PS
authors.lastname: Wang
authors.forename: Chao
authors.initials: C
authors.lastname: Wang
authors.forename: Liu-Zhu
authors.initials: LZ
authors.lastname: Gong