title: Fragment-based molecular design of new competitive dengue Den2 Ns2b/Ns3 inhibitors from the components of fingerroot (Boesenbergia rotunda).
authors.affiliation: Department of Chemistry, Faculty of Science, University of Malaya Lembah Pantai, Kuala Lumpur, Malaysia.
authors.forename: Neni
authors.initials: N
authors.lastname: Frimayanti
authors.forename: Sharifuddin M
authors.initials: SM
authors.lastname: Zain
authors.forename: Vannajan Sanghiran
authors.initials: VS
authors.lastname: Lee
authors.forename: Habibah A
authors.initials: HA
authors.lastname: Wahab
authors.forename: Rohana
authors.initials: R
authors.lastname: Yusof
authors.forename: Noorsaadah
authors.initials: N
authors.lastname: Abd Rahman
mesh_terms: D020134:Catalytic Domain; D047188:Chalcones / Q000737:chemistry; D003715:Dengue / Q000188:drug therapy*; D003716:Dengue Virus / Q000235:genetics*; D015195:Drug Design; D006860:Hydrogen Bonding; D057927:Hydrophobic and Hydrophilic Interactions; D008024:Ligands; D008958:Models, Molecular; D012697:Serine Endopeptidases / Q000187:drug effects*; D015842:Serine Proteinase Inhibitors / Q000737:chemistry*; D017361:Viral Nonstructural Proteins / Q000037:antagonists & inhibitors*; D030521:Zingiberaceae / Q000737:chemistry*; D000085242:Viral Proteases
chemical_list: D047188:Chalcones; D008024:Ligands; D012697:Serine Endopeptidases; D015842:Serine Proteinase Inhibitors; D017361:Viral Nonstructural Proteins; C482884:panduratin A; C504449:NS3 protease, dengue virus; D000085242:Viral Proteases