title: Discordant drug susceptibility for mycobacterium tuberculosis within families.
abstract: Children with presumed tuberculosis who are in contact with a multidrug-resistant source case should be treated according to the drug susceptibility of the source case's isolate. However, it is important to obtain a microbiologic diagnosis as it is possible for the child to have a different susceptibility profile to the source case. We present 2 such cases.
authors.affiliation: Desmond Tutu TB Centre, Faculty of Health Sciences, Stellenbosch University, and Tygerberg Children's Hospital, Tygerberg, South Africa. jseddon@sun.ac.za
authors.forename: James A
authors.initials: JA
authors.lastname: Seddon
authors.forename: Annemie M
authors.initials: AM
authors.lastname: Jordaan
authors.forename: Thomas C
authors.initials: TC
authors.lastname: Victor
authors.forename: H Simon
authors.initials: HS
authors.lastname: Schaaf
mesh_terms: D000995:Antitubercular Agents / Q000494:pharmacology*; D002675:Child, Preschool; D005192:Family Health; D005260:Female; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D009169:Mycobacterium tuberculosis / Q000187:drug effects* / Q000302:isolation & purification*; D014376:Tuberculosis / Q000382:microbiology*
chemical_list: D000995:Antitubercular Agents