title: No allergic reaction after TKA in a chrome-cobalt-nickel-sensitive patient: case report and review of the literature.
abstract: Hypersensitivity to metallic implants remains relatively unpredictable and poorly understood. Although 20-25 % of total joint arthroplasty patients develop metal sensitivity, only a few highly susceptible persons (<1 %) exhibit symptoms. We present a case report of a fifty-two-year-old woman with a preoperatively documented metal allergy who underwent bilateral total knee arthroplasty using a titanium-niobium-coated implant on one side and a chrome-cobalt implant on the other side because of a logistics problem. At 2-year follow-up, no clinical symptoms of allergy or loosening of the implant were observed. Level of evidence IV.
authors.affiliation: Department of Orthopaedic Surgery, Saint Luc University Hospital, Avenue Hippocrate 10, 1200, Brussels, Belgium. emmanuel.thienpont@uclouvain.be
authors.forename: Emmanuel
authors.initials: E
authors.lastname: Thienpont
authors.forename: Yorick
authors.initials: Y
authors.lastname: Berger
mesh_terms: D001168:Arthritis / Q000601:surgery*; D019645:Arthroplasty, Replacement, Knee; D001672:Biocompatible Materials / Q000009:adverse effects*; D002858:Chromium Alloys / Q000009:adverse effects*; D003035:Cobalt / Q000009:adverse effects*; D005260:Female; D006801:Humans; D006967:Hypersensitivity / Q000209:etiology*; D007719:Knee Joint; D007720:Knee Prosthesis; D008875:Middle Aged; D009532:Nickel / Q000009:adverse effects*; D011474:Prosthesis Design
chemical_list: D001672:Biocompatible Materials; D002858:Chromium Alloys; D003035:Cobalt; D009532:Nickel