title: An unusual human papillomavirus type 82 detection in laryngeal squamous cell carcinoma: case report and review of literature.
abstract: Squamous cell carcinoma (SCC) of the larynx is extremely rare in adolescent or younger adult and typically has an aggressive nature. The mechanism of laryngeal oncogenesis is complex and little is known about the role of human papillomaviruses (HPVs) in SCC in young age. HPV infection may occur during birth or latter by oro-genital contact. Most HPV genotypes detected were HPV 6, 11, 16, 18, 33 and 51. Herein, we report a case of invasive laryngeal SCC expressing an HPV 82 in an 18 year-old man with a history of unexplored severe acute dysphonia that started in early childhood.
authors.affiliation: Laboratoire de Virologie, Hôpital Européen Georges Pompidou (HEGP), Assistance Publique-Hôpitaux de Paris (AP-HP), Université Paris Descartes Sorbonne Paris Cité, Paris, France. ali.simohamed@egp.aphp.fr
authors.forename: Ali
authors.initials: A
authors.lastname: Si-Mohamed
authors.forename: Cécile
authors.initials: C
authors.lastname: Badoual
authors.forename: Stéphane
authors.initials: S
authors.lastname: Hans
authors.forename: Hélène
authors.initials: H
authors.lastname: Péré
authors.forename: Eric
authors.initials: E
authors.lastname: Tartour
authors.forename: Daniel
authors.initials: D
authors.lastname: Brasnu
mesh_terms: D000293:Adolescent; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000821:virology*; D005838:Genotype; D006651:Histocytochemistry; D006801:Humans; D007150:Immunohistochemistry; D007822:Laryngeal Neoplasms / Q000473:pathology / Q000821:virology*; D007830:Larynx / Q000473:pathology / Q000821:virology; D008297:Male; D008853:Microscopy; D027383:Papillomaviridae / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification*; D055815:Young Adult