title: [Spirulina, exercise and serum glucose control in diabetic rats].
abstract: OBJECTIVE
  The objective of this study was to analyze the effect of Spirulina and/or exercise training in the control of serum glucose homeostasis in diabetic rats.
  
  
  METHODS
  Young Wistar rats were induced to diabetes by intravenous alloxan administration and separated into four groups: diabetic control (DC), diabetic Spirulina (DS), diabetic exercise (DE) and diabetic exercise Spirulina (DES).
  
  
  RESULTS
  There were no differences between groups with respect to: body weight, food intake, glucose tolerance, insulin tolerance and blood lactate concentrations during a swimming effort test. DS group showed lower insulin concentrations when compared with DC (pancreas) and DE and DES (serum).
  
  
  CONCLUSIONS
  The protocols of exercise and supplementation with Spirulina used in the present study were not able to improve serum glucose homeostasis in diabetic rats.
authors.affiliation: Departamento de Educação Física, Instituto de Biociências, Universidade Estadual Paulista, Rio Claro, SP, Brasil. leandropereiram@hotmail.com
authors.forename: Leandro Pereira de
authors.initials: LP
authors.lastname: Moura
authors.forename: André Luiz Demantova
authors.initials: AL
authors.lastname: Gurjão
authors.forename: José Claudio
authors.initials: JC
authors.lastname: Jambassi Filho
authors.forename: Julio
authors.initials: J
authors.lastname: Mizuno
authors.forename: Clara
authors.initials: C
authors.lastname: Suemi
authors.forename: Maria Alice Rostom de
authors.initials: MA
authors.lastname: Mello
mesh_terms: D000704:Analysis of Variance; D000818:Animals; D001786:Blood Glucose / Q000378:metabolism*; D003921:Diabetes Mellitus, Experimental / Q000139:chemically induced / Q000378:metabolism / Q000517:prevention & control*; D019587:Dietary Supplements / Q000009:adverse effects*; D004195:Disease Models, Animal; D007004:Hypoglycemic Agents / Q000494:pharmacology*; D007328:Insulin / Q000378:metabolism*; D010805:Physical Conditioning, Animal / Q000009:adverse effects*; D011897:Random Allocation; D051381:Rats; D017208:Rats, Wistar; D053545:Spirulina
chemical_list: D001786:Blood Glucose; D007004:Hypoglycemic Agents; D007328:Insulin