title: Integration of local and systemic signaling pathways for plant N responses.
abstract: Nitrogen (N) is an essential macronutrient and a signal that has profound impacts on plant growth and development. In order to cope with changing N regimes in the soil, plants have developed complex regulatory mechanisms that involve short-range and long-range signaling pathways. These pathways act at the cellular and whole plant scale to coordinate plant N metabolism, growth and development according to external and internal N status. Although molecular components of local and systemic N signaling have been identified and characterized, an integrated view of how plants coordinate and organize the N response is still lacking. In this review, we discuss recent advances toward understanding the mechanisms of local and systemic N responses and provide an integrated model for how these responses are orchestrated.
authors.affiliation: FONDAP Center for Genome Regulation, Millennium Nucleus Center for Plant Functional Genomics, Departamento de Genética Molecular y Microbiología, Pontificia Universidad Católica de Chile, Alameda 340, Santiago, Chile.
authors.forename: José M
authors.initials: JM
authors.lastname: Alvarez
authors.forename: Elena A
authors.initials: EA
authors.lastname: Vidal
authors.forename: Rodrigo A
authors.initials: RA
authors.lastname: Gutiérrez
mesh_terms: D003583:Cytokinins / Q000378:metabolism; D009566:Nitrates / Q000378:metabolism; D009584:Nitrogen / Q000378:metabolism*; D010944:Plants / Q000378:metabolism*; D015398:Signal Transduction / Q000502:physiology
chemical_list: D003583:Cytokinins; D009566:Nitrates; D009584:Nitrogen