title: Homeopathy in chronic sinusitis: a prospective multi-centric observational study.
abstract: OBJECTIVE
  The primary objective was to ascertain the therapeutic usefulness of homeopathic medicine in the management of chronic sinusitis (CS).
  
  
  METHODS
  Multicentre observational study at Institutes and Units of the Central Council for Research in Homoeopathy, India. Symptoms were assessed using the chronic sinusitis assessment score (CSAS). 17 pre-defined homeopathic medicines were shortlisted for prescription on the basis of repertorisation for the pathological symptoms of CS. Regimes and adjustment of regimes in the event of a change of symptoms were pre-defined. The follow-up period was for 6 months. Statistical analysis was done using SPSS version 16.
  
  
  RESULTS
  628 patients suffering from CS confirmed on X-ray were enrolled from eight Institutes and Units of the Central Council for Research in Homoeopathy. All 550 patients with at least one follow-up assessment were analyzed. There was a statistically significant reduction in CSAS (P = 0.0001, Friedman test) after 3 and 6 months of treatment. Radiological appearances also improved. A total of 13 out of 17 pre-defined medicines were prescribed in 550 patients, Sil. (55.2% of 210), Calc. (62.5% of 98), Lyc. (69% of 55), Phos. (66.7% of 45) and Kali iod. (65% of 40) were found to be most useful having marked improvement. 4/17 medicines were never prescribed. No complications were observed during treatment.
  
  
  CONCLUSIONS
  Homeopathic treatment may be effective for CS patients. Controlled trials are required for further validation.
authors.affiliation: Central Council for Research in Homoeopathy, New Delhi, India.
authors.forename: Chaturbhuja
authors.initials: C
authors.lastname: Nayak
authors.forename: Vikram
authors.initials: V
authors.lastname: Singh
authors.forename: V P
authors.initials: VP
authors.lastname: Singh
authors.forename: Praveen
authors.initials: P
authors.lastname: Oberai
authors.forename: Varanasi
authors.initials: V
authors.lastname: Roja
authors.forename: Shashi Shekhar
authors.initials: SS
authors.lastname: Shitanshu
authors.forename: M N
authors.initials: MN
authors.lastname: Sinha
authors.forename: Deepti
authors.initials: D
authors.lastname: Deewan
authors.forename: B C
authors.initials: BC
authors.lastname: Lakhera
authors.forename: Sunil
authors.initials: S
authors.lastname: Ramteke
authors.forename: Subhash
authors.initials: S
authors.lastname: Kaushik
authors.forename: Sarabjit
authors.initials: S
authors.lastname: Sarkar
authors.forename: N R
authors.initials: NR
authors.lastname: Mandal
authors.forename: P G
authors.initials: PG
authors.lastname: Mohanan
authors.forename: J R
authors.initials: JR
authors.lastname: Singh
authors.forename: Sabyasachi
authors.initials: S
authors.lastname: Biswas
authors.forename: Georgekutty
authors.initials: G
authors.lastname: Mathew
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002908:Chronic Disease; D005260:Female; D006705:Homeopathy / Q000379:methods*; D006801:Humans; D007194:India; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011859:Radiography; D012852:Sinusitis / Q000000981:diagnostic imaging / Q000188:drug therapy*; D016896:Treatment Outcome; D055815:Young Adult