title: Nodular lesions of self-healing juvenile cutaneous mucinosis: a pitfall!
abstract: Self-healing juvenile cutaneous mucinosis (SHJCM) is a rare disorder of unknown origin, which occurs in children in good health. It is characterized by the multiplication of transient cutaneous papules and nodules, mainly located on the head and periarticular areas that spontaneously resolve. Histological features of SHJCM have been well described; therefore, the diagnosis is usually made easily when papules are biopsied. We report a series of 3 new cases of SHJCM presenting mainly with nodular lesions. Histological examination of these nodules showed either lesions consistent with nodular or proliferative fasciitis or nonspecific panniculitis. Mucinous deposits were present but often inconspicuous, so could be disregarded. We wanted to emphasize this misleading presentation because a biopsy for histological examination is always mandatory in cases of proliferating nodules to rule out malignant tumors. Therefore, the diagnosis always requires discussion between pathologists and clinicians to rapidly reassure the parents and avoid inappropriate therapy.
authors.affiliation: Department of Dermatology, Centre Hospitalier Universitaire de Caen, Université de Caen Basse-Normandie, UFR de Médecine, Caen, France.
authors.forename: Morgane
authors.initials: M
authors.lastname: Barreau
authors.forename: Anne
authors.initials: A
authors.lastname: Dompmartin-Blanchère
authors.forename: Roula
authors.initials: R
authors.lastname: Jamous
authors.forename: Myrna
authors.initials: M
authors.lastname: Chababi
authors.forename: Boutros
authors.initials: B
authors.lastname: Soutou
authors.forename: Judith
authors.initials: J
authors.lastname: Reynier-Rezzi
authors.forename: Anne-Laure
authors.initials: AL
authors.lastname: Laplaud
authors.forename: Aurélie
authors.initials: A
authors.lastname: Acher
authors.forename: Julien
authors.initials: J
authors.lastname: Rod
authors.forename: Corinne
authors.initials: C
authors.lastname: Jeanne-Pasquier
authors.forename: Sylvie
authors.initials: S
authors.lastname: Fraitag
mesh_terms: D015415:Biomarkers / Q000032:analysis; D001706:Biopsy; D049109:Cell Proliferation; D002675:Child, Preschool; D003951:Diagnostic Errors / Q000517:prevention & control*; D005208:Fasciitis / Q000209:etiology / Q000473:pathology; D006801:Humans; D007150:Immunohistochemistry; D007223:Infant; D008297:Male; D017520:Mucinoses / Q000150:complications / Q000378:metabolism / Q000473:pathology*; D009077:Mucins / Q000032:analysis*; D015434:Panniculitis / Q000209:etiology / Q000473:pathology; D011237:Predictive Value of Tests; D012075:Remission, Spontaneous; D012867:Skin / Q000737:chemistry / Q000473:pathology*; D012878:Skin Neoplasms / Q000473:pathology*; D013997:Time Factors
chemical_list: D015415:Biomarkers; D009077:Mucins