title: Cosavirus infection in persons with and without gastroenteritis, Brazil.
abstract: To determine possible cosavirus association with clinical disease, we used real-time reverse transcription PCR to test children and HIV-positive adults in Brazil with and without gastroenteritis. Thirteen (3.6%) of 359 children with gastroenteritis tested positive, as did 69 (33.8%) of 204 controls. Low prevalence, frequent viral co-infections, and low fecal cosavirus RNA concentrations argue against human pathogenicity.
authors.affiliation: University of Bonn Medical Centre, Bonn, Germany.
authors.forename: Andreas
authors.initials: A
authors.lastname: Stöcker
authors.forename: Breno Frederico de Carvalho Dominguez
authors.initials: BF
authors.lastname: Souza
authors.forename: Tereza Cristina Medrado
authors.initials: TC
authors.lastname: Ribeiro
authors.forename: Eduardo Martins
authors.initials: EM
authors.lastname: Netto
authors.forename: Luciana Oliveira
authors.initials: LO
authors.lastname: Araujo
authors.forename: Jefferson Ivan
authors.initials: JI
authors.lastname: Corrêa
authors.forename: Patrícia Silva
authors.initials: PS
authors.lastname: Almeida
authors.forename: Angela Peixoto
authors.initials: AP
authors.lastname: de Mattos
authors.forename: Hugo da Costa
authors.initials: Hda C
authors.lastname: Ribeiro
authors.forename: Diana Brasil
authors.initials: DB
authors.lastname: Pedral-Sampaio
authors.forename: Christian
authors.initials: C
authors.lastname: Drosten
authors.forename: Jan Felix
authors.initials: JF
authors.lastname: Drexler
mesh_terms: D000328:Adult; D001938:Brazil / Q000453:epidemiology; D016022:Case-Control Studies; D002648:Child; D015331:Cohort Studies; D060085:Coinfection; D003967:Diarrhea / Q000453:epidemiology* / Q000821:virology; D005243:Feces / Q000821:virology; D005759:Gastroenteritis / Q000453:epidemiology* / Q000821:virology; D005814:Genes, Viral; D006801:Humans; D008969:Molecular Sequence Data; D010849:Picornaviridae / Q000235:genetics / Q000302:isolation & purification*; D010850:Picornaviridae Infections / Q000453:epidemiology* / Q000821:virology; D015995:Prevalence; D017422:Sequence Analysis, DNA