title: [Antibacterial activity of rare Streptomyces species against clinical resistant bacteria].
abstract: In the search for new antibiotics from Steptomyces, investigating extremes habitats enhances the probability of isolating novel producers. In this context, the antibacterial activity of four Streptomyces strains isolated from Ezzmoul saltpans was studied. Two of them showed antibacterial activity against antibiotic's resistant bacteria (Bacillus cereus: β-lactamines and sulfamides resistant, Streptococcus faecalis: penicillin, tetracycline and cotrimoxazole resistant, and Staphylococcus aureus Mu 50: vancomycine resistant). The most active Streptomyces strain produces one type of polar bioactive molecules that resists to temperature variation and light exposition. Its activity appears in the first culture day and reaches its maximal value in the fourth day. The second strain presents themoresistant activity that reaches its maximal value in the first culture day. It produces two types of bioactive molecules, one is polar and the second is non polar (according to thin layer chromatography technique results).
authors.affiliation: Université Mentouri Constantine 4, Constantine, Algérie. faizasasi@yahoo.fr
authors.forename: Faiza
authors.initials: F
authors.lastname: Boughachiche
authors.forename: Sihem
authors.initials: S
authors.lastname: Reghioua
authors.forename: Habiba
authors.initials: H
authors.lastname: Zerizer
authors.forename: Abderrahmane
authors.initials: A
authors.lastname: Boulahrouf
mesh_terms: D000900:Anti-Bacterial Agents / Q000032:analysis / Q000302:isolation & purification* / Q000378:metabolism* / Q000493:pharmacokinetics; D000898:Antibiosis / Q000502:physiology*; D001409:Bacillus cereus / Q000187:drug effects / Q000254:growth & development; D024901:Drug Resistance, Multiple, Bacterial / Q000187:drug effects / Q000502:physiology; D004355:Drug Stability; D013293:Enterococcus faecalis / Q000187:drug effects / Q000254:growth & development; D008826:Microbial Sensitivity Tests; D055049:Salt Tolerance / Q000502:physiology; D012997:Solvents / Q000494:pharmacology; D013211:Staphylococcus aureus / Q000187:drug effects / Q000254:growth & development; D013302:Streptomyces / Q000737:chemistry / Q000378:metabolism* / Q000502:physiology*; D013696:Temperature
chemical_list: D000900:Anti-Bacterial Agents; D012997:Solvents