title: Inflammatory pseudotumor of the spleen: review of clinical presentation and diagnostic methods.
abstract: We describe a 91-year-old woman with a clinical history of invasive ductal carcinoma of the breast diagnosed in 1991 who was admitted because of dizziness, poor appetite, and some swelling and tenderness over her cheeks. The patient's initial work up revealed a 5-cm well-demarcated hypodense solid lesion in her spleen with abnormally intense uptake on PET/CT scan raising suspicion for malignancy i.e. breast metastasis versus lymphoma. Further review demonstrated the presence of this splenic lesion, though slightly smaller, on a CT scan from ten years earlier (2000). An ultrasonographic guided core needle splenic biopsy was performed and the pathology result revealed histological findings compatible with inflammatory pseudotumor of the spleen. As a result, unnecessary splenectomy was avoided.
authors.affiliation: Department of Diagnostic Radiology, University Hospitals Case Medical Center, Cleveland, OH 44106-5056, USA. hooman.yarmohammadi@uhhospitals.org
authors.forename: Hooman
authors.initials: H
authors.lastname: Yarmohammadi
authors.forename: Dean
authors.initials: D
authors.lastname: Nakamoto
authors.forename: Peter F
authors.initials: PF
authors.lastname: Faulhaber
authors.forename: John
authors.initials: J
authors.lastname: Miedler
authors.forename: Nami
authors.initials: N
authors.lastname: Azar
mesh_terms: D000369:Aged, 80 and over; D001707:Biopsy, Needle; D005260:Female; D006104:Granuloma, Plasma Cell / Q000000981:diagnostic imaging* / Q000473:pathology*; D006801:Humans; D064847:Multimodal Imaging; D049268:Positron-Emission Tomography; D013154:Spleen / Q000000981:diagnostic imaging* / Q000473:pathology*; D013158:Splenic Diseases / Q000175:diagnosis*; D014057:Tomography, X-Ray Computed