title: Successful case with hemophagocytic syndrome after living donor liver transplantation.
abstract: Hemophagocytic syndrome (HPS) is a rare but serious complication that is associated with hypercytokinemia caused by activated T lymphocytes and macrophages in immunologically compromised patients. Living donor liver transplantation (LDLT) between adults has been performed to compensate for the shortage of available organs. There have been some reports of HPS after LDLT but its prognosis is disappointingly poor. Herein, we report a case of HPS in a 53-year-old woman who underwent LDLT using a left lobe graft. HPS was diagnosed on postoperative day 6 and successfully treated with a steroid pulse. HPS is a fatal complication in immunologically compromised patients but its early diagnosis and appropriate treatment can lead to an improved outcome.
authors.affiliation: Department of Surgery, University of Tokushima, Tokushima, Japan.
authors.forename: Satoru
authors.initials: S
authors.lastname: Imura
authors.forename: Mitsuo
authors.initials: M
authors.lastname: Shimada
authors.forename: Yu
authors.initials: Y
authors.lastname: Saito
authors.forename: Shuichi
authors.initials: S
authors.lastname: Iwahashi
authors.forename: Jun
authors.initials: J
authors.lastname: Hanaoka
authors.forename: Hiroki
authors.initials: H
authors.lastname: Mori
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Ikemoto
authors.forename: Yuji
authors.initials: Y
authors.lastname: Morine
authors.forename: Tohru
authors.initials: T
authors.lastname: Utsunomiya
mesh_terms: D001706:Biopsy; D001856:Bone Marrow Examination; D005260:Female; D006801:Humans; D016031:Liver Transplantation / Q000009:adverse effects*; D019520:Living Donors; D051359:Lymphohistiocytosis, Hemophagocytic / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D008875:Middle Aged; D020551:Pulse Therapy, Drug; D013256:Steroids / Q000008:administration & dosage; D016896:Treatment Outcome
chemical_list: D013256:Steroids