title: Blood biomarkers in stroke: research and clinical practice.
abstract: Blood biomarkers may have applications in stroke diagnosis, outcome prediction, or treatment. In this article, we provide a focused review on some of the methodological challenges and potential developments of biomarkers in stroke. We review the approaches to the development of a diagnostic blood marker: a candidate marker approach, marker panels, and -omics. Then we examined the role of blood markers to predict recurrent stroke and treatment response in stroke.
authors.affiliation: Division of Clinical Neurosciences, Western General Hospital, University of Edinburgh, Edinburgh, UK. william.whiteley@ed.ac.uk
authors.forename: William
authors.initials: W
authors.lastname: Whiteley
authors.forename: Yingfang
authors.initials: Y
authors.lastname: Tian
authors.forename: Glen C
authors.initials: GC
authors.lastname: Jickling
mesh_terms: D015415:Biomarkers / Q000097:blood*; D002545:Brain Ischemia / Q000175:diagnosis*; D006801:Humans; D058990:Molecular Targeted Therapy; D018579:Patient Selection; D011379:Prognosis; D055502:Secondary Prevention; D020521:Stroke / Q000175:diagnosis* / Q000517:prevention & control
chemical_list: D015415:Biomarkers