title: [Study on in vitro susceptibility of Candida spp. isolated from blood culture].
abstract: In recent years the incidence of bloodstream infections due to Candida species has progressively increased, partly due to the more critical conditions of hospitalized patients. There has been a significant increase in immune-compromised, diabetic and/or elderly patients, also with venous access, with a subsequent increase in Candida species isolated from bloodstream infections. In 2009-2010 in the hospitals of Mestre and Venice we isolated 123 Candida species from bloodstream infections: 59 Candida albicans, 28 Candida parapsilosis, 12 Candida glabrata, 9 Candida tropicalis, and 4 Geotrichum capitatum, while the 11 others belong to 8 different species. We calculated MIC for the following antifungal agents: fluconazole, itraconazole, voriconazole, 5-flucytosine, amphotericin B and caspofungin.
authors.affiliation: Struttura Semplice Dipartimentale di Microbiologia, Ospedale dell'Angelo, Mestre, Venezia, Italy.
authors.forename: Stefano
authors.initials: S
authors.lastname: Grandesso
authors.forename: Barbara
authors.initials: B
authors.lastname: Sapino
authors.forename: Sandra
authors.initials: S
authors.lastname: Mazzuccato
authors.forename: Maria
authors.initials: M
authors.lastname: Solinas
authors.forename: Maria
authors.initials: M
authors.lastname: Bedin
authors.forename: Monica
authors.initials: M
authors.lastname: D'Angelo
authors.forename: Massimo
authors.initials: M
authors.lastname: Gion
mesh_terms: D000666:Amphotericin B / Q000494:pharmacology; D000935:Antifungal Agents / Q000494:pharmacology*; D001769:Blood / Q000382:microbiology; D002175:Candida / Q000145:classification / Q000187:drug effects* / Q000302:isolation & purification; D002177:Candidiasis / Q000188:drug therapy / Q000382:microbiology; D000077336:Caspofungin; D025141:Drug Resistance, Fungal; D054714:Echinocandins / Q000494:pharmacology; D015725:Fluconazole / Q000494:pharmacology; D005437:Flucytosine / Q000494:pharmacology; D006761:Hospitals; D006801:Humans; D066298:In Vitro Techniques; D017964:Itraconazole / Q000494:pharmacology; D055666:Lipopeptides; D008826:Microbial Sensitivity Tests / Q000379:methods; D011743:Pyrimidines / Q000494:pharmacology; D015203:Reproducibility of Results; D012307:Risk Factors; D014230:Triazoles / Q000494:pharmacology; D065819:Voriconazole
chemical_list: D000935:Antifungal Agents; D054714:Echinocandins; D055666:Lipopeptides; D011743:Pyrimidines; D014230:Triazoles; D017964:Itraconazole; D000666:Amphotericin B; D015725:Fluconazole; D005437:Flucytosine; D000077336:Caspofungin; D065819:Voriconazole