title: An unusual cause of widespread lytic bone lesions caused by sarcoidosis.
abstract: We present a case of a 59 year old asymptomatic lady who was found to have incidental findings of pulmonary, osseous and hepatic involvement with sarcoidosis. The osseous lesions were lytic and involved unusual sites such as the vertebrae and skull base. The initial clinical concern had been of multiple myeloma or disseminated metastases. Biopsy of material obtained following mediastinoscopy revealed chronic, non-necrotising granulomatous lymphadenopathy indicative of sarcoidosis. Cases such as this could greatly benefit from multidisciplinary team discussion particularly when the clinical picture is not typical of malignancy.
authors.affiliation: Department of Radiology, Freeman Hospital, Newcastle upon Tyne, UK. mehr75@doctors.org.uk
authors.forename: Pallavi
authors.initials: P
authors.lastname: Mehrotra
authors.forename: Michelle
authors.initials: M
authors.lastname: Muller
authors.forename: Bernard
authors.initials: B
authors.lastname: Higgins
authors.forename: Ivan
authors.initials: I
authors.lastname: Zammit-Maempel
mesh_terms: D001847:Bone Diseases / Q000150:complications* / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D033162:Incidental Findings; D008875:Middle Aged; D012507:Sarcoidosis / Q000150:complications* / Q000000981:diagnostic imaging*; D012886:Skull / Q000000981:diagnostic imaging / Q000473:pathology; D013131:Spine / Q000000981:diagnostic imaging / Q000473:pathology; D014057:Tomography, X-Ray Computed