title: Clinical disability progression and platelet GP IIb/IIIa values in patients with atopic myelitis.
abstract: We aimed to clarify the disability progression and platelet aggregative function in atopic myelitis (AM). Seventeen AM patients and 35 healthy controls were subjected to clinico-allergological evaluations and glycoprotein IIb/IIIa (GP IIb/IIIa) measurements using a VerifyNow assay system. In AM patients, the disease duration had significant positive correlations with the Kurtzke Expanded Disability Status Scale scores and Sensory Functional Scale scores. The GP IIb/IIIa values were significantly higher in AM patients than in controls as well as in females compared with males. AM is essentially a progressive disease affecting the sensory system, and involves an increased platelet aggregative function.
authors.affiliation: Department of Neurology, Neurological Institute, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
authors.forename: Gulibahaer
authors.initials: G
authors.lastname: Ainiding
authors.forename: Ken-ichiro
authors.initials: K
authors.lastname: Yamashita
authors.forename: Takako
authors.initials: T
authors.lastname: Torii
authors.forename: Konosuke
authors.initials: K
authors.lastname: Furuta
authors.forename: Noriko
authors.initials: N
authors.lastname: Isobe
authors.forename: Takuya
authors.initials: T
authors.lastname: Matsushita
authors.forename: Katsuhisa
authors.initials: K
authors.lastname: Masaki
authors.forename: Shoji
authors.initials: S
authors.lastname: Matsumoto
authors.forename: Jun-ichi
authors.initials: J
authors.lastname: Kira
mesh_terms: D004185:Disability Evaluation; D018450:Disease Progression; D005260:Female; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000276:immunology / Q000378:metabolism / Q000503:physiopathology; D008297:Male; D009187:Myelitis / Q000276:immunology* / Q000378:metabolism* / Q000503:physiopathology; D010974:Platelet Aggregation / Q000276:immunology; D019039:Platelet Glycoprotein GPIIb-IIIa Complex / Q000378:metabolism*; D012677:Sensation / Q000276:immunology; D015854:Up-Regulation / Q000276:immunology
chemical_list: D019039:Platelet Glycoprotein GPIIb-IIIa Complex