title: Chemistry and biology of acylfulvenes: sesquiterpene-derived antitumor agents.
authors.affiliation: ETH Zurich, Institute of Food, Nutrition and Health, Zurich, Switzerland.
authors.forename: Marina
authors.initials: M
authors.lastname: Tanasova
authors.forename: Shana J
authors.initials: SJ
authors.lastname: Sturla
mesh_terms: D000477:Alkylating Agents / Q000737:chemistry / Q000494:pharmacology; D000818:Animals; D000970:Antineoplastic Agents / Q000737:chemistry* / Q000493:pharmacokinetics / Q000494:pharmacology*; D001388:Aziridines / Q000737:chemistry; D002986:Clinical Trials as Topic; D003521:Cyclopropanes / Q000737:chemistry; D004249:DNA Damage / Q000187:drug effects; D004791:Enzyme Inhibitors / Q000737:chemistry / Q000494:pharmacology; D005980:Glutathione Reductase / Q000037:antagonists & inhibitors; D006801:Humans; D051379:Mice; D012717:Sesquiterpenes / Q000737:chemistry* / Q000494:pharmacology; D013141:Spiro Compounds / Q000737:chemistry* / Q000494:pharmacology*; D014018:Tissue Distribution; D023041:Xenograft Model Antitumor Assays
chemical_list: D000477:Alkylating Agents; D000970:Antineoplastic Agents; D001388:Aziridines; D003521:Cyclopropanes; D004791:Enzyme Inhibitors; D012717:Sesquiterpenes; D013141:Spiro Compounds; C079422:acylfulvene; C033132:aziridine; C030797:cyclopropane; D005980:Glutathione Reductase