title: Cecorraphy in single layer using polypropylene and poliglecaprone 25 threads: comparative study in rats.
abstract: OBJECTIVE
  To compare sutures with polypropylene and poliglecaprone 25 after partial cecotomy in rats.
  
  
  METHODS
  Thirty six rats divided into two groups, A and B, of 18 animals; each group was also divided into three subgroups of six animals sacrificed at 4(th), 7(th) and 14(th) days after surgery. Were studied the mortality, morbidity, complications attributable to sutures, macroscopy, optical microscopy and measurement of hydroxyproline at the level of the suture.
  
  
  RESULTS
  There were no deaths or wound complications such as hematoma, seroma, abscess, evisceration or eventration. On microscopic evaluation reepithelization, coaptation and inflammation in both groups did not differ significantly. The average rate of tissue hydroxyproline found in the samples on the 4(th) day after surgery, was 21.38 mg/g tissue for group A and 16.68 mg/g for group B; on day 7 after surgery, the average was 15.64 mg/g tissue for group A and 26.53 mg/g for group B; on day 14, the average was 8.09 mg/g tissue for group A and 25.07 mg/g for group B.
  
  
  CONCLUSIONS
  There were no differences on clinical evolution, macroscopic aspect, microscopic data and hydroxyproline concentration on both sutures.
authors.affiliation: FEPAR, Curitiba-PR, Brazil. malafaia@evangelico.org.br
authors.forename: Fernando Issamu
authors.initials: FI
authors.lastname: Tabushi
authors.forename: Luiz Masakatso
authors.initials: LM
authors.lastname: Nomura
authors.forename: Osvaldo
authors.initials: O
authors.lastname: Malafaia
authors.forename: Jurandir Marcondes
authors.initials: JM
authors.lastname: Ribas-Filho
authors.forename: Benur
authors.initials: B
authors.lastname: Polonio
authors.forename: João Carlos Domingues
authors.initials: JC
authors.lastname: Repka
authors.forename: Sergio
authors.initials: S
authors.lastname: Ioshii
authors.forename: Octavio Antonio Azevedo da
authors.initials: OA
authors.lastname: Costa-Filho
mesh_terms: D000818:Animals; D002432:Cecum / Q000601:surgery* / Q000648:ultrastructure; D004146:Dioxanes / Q000009:adverse effects*; D006909:Hydroxyproline / Q000032:analysis*; D008297:Male; D023421:Models, Animal; D011091:Polyesters / Q000009:adverse effects*; D011126:Polypropylenes; D011184:Postoperative Period; D011897:Random Allocation; D051381:Rats; D017208:Rats, Wistar; D013536:Suture Techniques / Q000295:instrumentation*; D013537:Sutures / Q000009:adverse effects
chemical_list: D004146:Dioxanes; D011091:Polyesters; D011126:Polypropylenes; C095495:glycolide E-caprolactone copolymer; D006909:Hydroxyproline