title: [Occurrence of severe cardiac alterations in Amanita proxima poisoning: two original observations].
abstract: Amanita proxima is one species of white mushroom which can induce poisonings called in France "proximien" syndrome. The clinical feature of "proximien" syndrome is mainly characterized by early digestive troubles, mild hepatic cytolysis and late renal impairment. A cardiac insult has never been reported in such a circumstance. The authors describe herein two cases of white mushroom poisoning occurred in the Mediterranean French coast with a typical clinical feature of "proximien" syndrome plus secondary development of severe cardiac alterations. The outcome was good for the two patients thanks to symptomatic treatment. The cases reported here suggest that A. proxima have a potential severe cardiac toxicity leading to include early and precise cardiac examination in the management of patients poisoned by these mushrooms.
authors.affiliation: Service de réanimation polyvalente, centre hospitalier intercommunal, 83608 Fréjus-Saint-Raphaël, France.
authors.forename: A
authors.initials: A
authors.lastname: Besancon
authors.forename: C
authors.initials: C
authors.lastname: Schmitt
authors.forename: M
authors.initials: M
authors.lastname: Glaizal
authors.forename: L
authors.initials: L
authors.lastname: Tichadou
authors.forename: K
authors.initials: K
authors.lastname: Klouche
authors.forename: M
authors.initials: M
authors.lastname: Hayek-Lanthois
authors.forename: L
authors.initials: L
authors.lastname: de Haro
mesh_terms: D000318:Adrenergic beta-Agonists / Q000627:therapeutic use; D000328:Adult; D000545:Amanita; D004232:Diuretics; D004280:Dobutamine / Q000627:therapeutic use; D004562:Electrocardiography; D005260:Female; D005665:Furosemide / Q000627:therapeutic use; D006333:Heart Failure / Q000139:chemically induced* / Q000000981:diagnostic imaging / Q000503:physiopathology; D017583:Hemodiafiltration; D006439:Hemodynamics / Q000502:physiology; D006801:Humans; D008133:Long QT Syndrome / Q000139:chemically induced; D008297:Male; D008875:Middle Aged; D009145:Mushroom Poisoning / Q000000981:diagnostic imaging / Q000503:physiopathology*; D009325:Nausea / Q000139:chemically induced; D012151:Resuscitation; D012770:Shock, Cardiogenic / Q000139:chemically induced / Q000628:therapy; D014463:Ultrasonography; D018487:Ventricular Dysfunction, Left / Q000139:chemically induced / Q000000981:diagnostic imaging / Q000503:physiopathology
chemical_list: D000318:Adrenergic beta-Agonists; D004232:Diuretics; D004280:Dobutamine; D005665:Furosemide