title: Synthesis, crystal structures and reactivity of copper(I) amidate complexes with aryl halides: insight into copper(I)-catalyzed Goldberg reaction.
abstract: In this paper, copper(I) amidate complexes (2-3), proposed intermediates in copper-catalyzed Goldberg reaction, have been prepared and characterized by elemental analysis, IR, (1)H NMR and X-ray crystallography. Ancillary ligand bis(diphenylphosphino)ferrocene (dppf) has contributed greatly to the stability of the copper-amidate complexes due to its strong chelating ability and weak intermolecular interactions. Thermal gravimetric analyses are carried out to determine the thermal competency of complexes 2-3 as the intermediates of the high-temperature Goldberg reactions. Reaction of complexes 2 and 3 with aryl halides generates the N-arylation products 5-8, accompanied by the formation of a copper(I) complex Cu(dppf)X (X = I or Br) 4, which has been determined by LC-MS analysis. These results provide new evidence for the mechanism of copper(I)-catalyzed Goldberg reaction.
authors.affiliation: The Key Laboratory of Food Colloids and Biotechnology, Ministry of Education, School of Chemical and Material Engineering, Jiangnan University, Wuxi, 214122, P.R. China.
authors.forename: Xinfang
authors.initials: X
authors.lastname: Liu
authors.forename: Songlin
authors.initials: S
authors.lastname: Zhang
authors.forename: Yuqiang
authors.initials: Y
authors.lastname: Ding
mesh_terms: D002384:Catalysis; D060326:Chemistry Techniques, Synthetic; D003300:Copper / Q000737:chemistry*; D018360:Crystallography, X-Ray; D006219:Halogens / Q000737:chemistry*; D008958:Models, Molecular; D008968:Molecular Conformation; D009942:Organometallic Compounds / Q000138:chemical synthesis* / Q000737:chemistry*; D013696:Temperature
chemical_list: D006219:Halogens; D009942:Organometallic Compounds; D003300:Copper