title: Lipid lowering with dietary supplements: focus on diabetes.
abstract: Cardiovascular disease (CVD) is the predominant cause of mortality in type 2 diabetic (T2DM) patients. Dyslipidemia is a modifiable risk factor that should be treated early for CVD prevention. Further, dietary supplement intake is increasing in popularity worldwide. This review examines the recent meta-analyses and clinical studies on dietary supplements, specifically psyllium, garlic and green tea, on plasma lipids levels and glycemic control, as well as other potential CVD risk factors in T2DM patients. Generally, results demonstrate that psyllium supplements improve lipid profiles as well as glycemic control beyond a traditional diet in patients with T2DM. On the other hand, the results on the usefulness of garlic and green tea supplementation for dyslipidemia and hyperglycemia are uncertain. Overall, the addition of dietary supplements may be a therapeutic alternative to lower CVD risk factors in T2DM; however, more well-designed intervention studies are needed to assess the benefit of these dietary supplements.
authors.affiliation: Institute of Nutraceuticals and Functional Foods, Laval University, Pavillon des Services, Bureau 2602, 2440, Boulevard Hochelaga, Québec, Canada G1V 0A6. iwona.rudkowska@fsaa.ulaval.ca
authors.forename: Iwona
authors.initials: I
authors.lastname: Rudkowska
mesh_terms: D002318:Cardiovascular Diseases / Q000209:etiology / Q000517:prevention & control; D003924:Diabetes Mellitus, Type 2 / Q000097:blood*; D019587:Dietary Supplements; D005737:Garlic; D006801:Humans; D006943:Hyperglycemia / Q000150:complications / Q000517:prevention & control*; D006949:Hyperlipidemias / Q000150:complications / Q000517:prevention & control*; D000960:Hypolipidemic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D011620:Psyllium / Q000627:therapeutic use; D013662:Tea
chemical_list: D000960:Hypolipidemic Agents; D013662:Tea; D011620:Psyllium