title: Subgaleal hemorrhage in a neonate with factor X deficiency following a non-traumatic cesarean section.
abstract: This case report describes a term infant born by a non-traumatic, non-instrumented cesarean section that presented with respiratory failure and severe metabolic acidosis secondary to subgaleal hemorrhage (SGH). Further evaluation revealed a functional factor X deficiency that was initially treated with fresh frozen plasma infusions. This report is significant for the occurrence of a SGH in a non-traumatic delivery and emphasizes the importance of obtaining a coagulopathy evaluation in patients with similar presentations. In addition, this case suggests that the mechanism of injury that causes SGH may occur more frequently than previously thought, but does not become clinically significant in patients without an underlying coagulopathy.
authors.affiliation: The Perinatal Institute, Section of Neonatology, Perinatal and Pulmonary Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
authors.forename: E A
authors.initials: EA
authors.lastname: Wetzel
authors.forename: P S
authors.initials: PS
authors.lastname: Kingma
mesh_terms: D000138:Acidosis / Q000209:etiology* / Q000628:therapy; D002543:Cerebral Hemorrhage / Q000175:diagnosis* / Q000628:therapy; D002585:Cesarean Section; D003937:Diagnosis, Differential; D004453:Echoencephalography; D005164:Factor IX / Q000008:administration & dosage; D005171:Factor X Deficiency / Q000175:diagnosis* / Q000628:therapy; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007363:Intensive Care Units, Neonatal; D008297:Male; D010521:Periosteum; D011247:Pregnancy; D012131:Respiratory Insufficiency / Q000209:etiology* / Q000628:therapy; D012886:Skull
chemical_list: D005164:Factor IX