title: Photocaged permeability: a new strategy for controlled drug release.
abstract: Light is used to release a drug from a cell impermeable small molecule, uncloaking its cytotoxic effect on cancer cells.
authors.affiliation: Department of Chemistry, Virginia Commonwealth University (VCU), 1001 West Main Street, P. O. Box 842006, Richmond, VA 23284, USA.
authors.forename: M Michael
authors.initials: MM
authors.lastname: Dcona
authors.forename: Deboleena
authors.initials: D
authors.lastname: Mitra
authors.forename: Rachel W
authors.initials: RW
authors.lastname: Goehe
authors.forename: David A
authors.initials: DA
authors.lastname: Gewirtz
authors.forename: Deborah A
authors.initials: DA
authors.lastname: Lebman
authors.forename: Matthew C T
authors.initials: MC
authors.lastname: Hartman
mesh_terms: D000970:Antineoplastic Agents / Q000737:chemistry; D002460:Cell Line; D003692:Delayed-Action Preparations / Q000737:chemistry; D004317:Doxorubicin / Q000737:chemistry*; D005434:Flow Cytometry; D006801:Humans; D008027:Light; D008954:Models, Biological; D015394:Molecular Structure; D009282:Naphthalenesulfonates / Q000737:chemistry*; D010539:Permeability; D004364:Pharmaceutical Preparations / Q000737:chemistry
chemical_list: D000970:Antineoplastic Agents; D003692:Delayed-Action Preparations; D009282:Naphthalenesulfonates; D004364:Pharmaceutical Preparations; C063126:5-((2-aminoethyl)amino)naphthalene-1-sulfonic acid; D004317:Doxorubicin