title: Costs and cost-effectiveness of hematopoietic cell transplantation.
abstract: Interest is growing in economic and comparative effectiveness analyses, with increasing emphasis on optimizing healthcare resources and costs. Limited information is available on the economic aspects of hematopoietic cell transplantation (HCT). We review contemporary literature on the costs and cost-effectiveness of HCT in the United States and worldwide. Published studies confirm the high costs associated with HCT, although the reported costs are highly variable, related to the differing methodologies used across studies. We examine the challenges in reviewing costs and cost-effectiveness across studies specific to HCT and highlight factors identified as associated with higher costs of HCT. We also discuss opportunities for future research in this area.
authors.affiliation: Health Services Research Program, National Marrow Donor Program, Minneapolis, Minnesota 55416, USA.
authors.forename: Jaime M
authors.initials: JM
authors.lastname: Preussler
authors.forename: Ellen M
authors.initials: EM
authors.lastname: Denzen
authors.forename: Navneet S
authors.initials: NS
authors.lastname: Majhail
mesh_terms: D000328:Adult; D002648:Child; D036101:Cord Blood Stem Cell Transplantation / Q000191:economics*; D003362:Cost-Benefit Analysis; D005060:Europe; D017048:Health Care Costs; D018380:Hematopoietic Stem Cell Transplantation / Q000191:economics*; D006801:Humans; D007297:Inpatients; D007564:Japan; D010045:Outpatients; D014182:Transplantation, Autologous; D014184:Transplantation, Homologous; D014481:United States