title: Genetic polymorphism of serum complement components in the chimpanzee.
abstract: Significant polymorphism of serum complement components Bf, C2, C3, C6, and C8 in the chimpanzee has been demonstrated. The data are consistent with the hypothesis that C2 and Bf are closely linked to ChLA and argue against close linkage of ChLA to C3 or to C8, as in man. In addition, a blank allele for C6 and C6 deficiency was detected in several chimps.
authors.affiliation: Department of Medicine, Children's Hospital Medical Center, Boston, Massachusetts 02115, USA.
authors.forename: D
authors.initials: D
authors.lastname: Raum
authors.forename: H
authors.initials: H
authors.lastname: Balner
authors.forename: B H
authors.initials: BH
authors.lastname: Petersen
authors.forename: C A
authors.initials: CA
authors.lastname: Alper
mesh_terms: D000818:Animals; D003167:Complement Activation / Q000276:immunology; D003175:Complement C2 / Q000235:genetics* / Q000276:immunology; D003176:Complement C3 / Q000235:genetics* / Q000276:immunology; D003183:Complement C6 / Q000235:genetics* / Q000276:immunology; D003185:Complement C8 / Q000235:genetics* / Q000276:immunology; D003165:Complement System Proteins / Q000235:genetics* / Q000276:immunology; D006801:Humans; D002679:Pan troglodytes / Q000235:genetics* / Q000276:immunology; D010375:Pedigree; D011110:Polymorphism, Genetic; D044967:Serum / Q000276:immunology
chemical_list: D003175:Complement C2; D003176:Complement C3; D003183:Complement C6; D003185:Complement C8; D003165:Complement System Proteins