title: Estrus response and follicular development in Boer does synchronized with flugestone acetate and PGF2α or their combination with eCG or FSH.
abstract: The effects of different estrus synchronization techniques on follicular development and estrus response were studied in 81 nulliparous Boer does. The does were divided into nine groups. Eight of the nine groups were synchronized with prostaglandin F2-alpha (PGF(2α)) or flugestone acetate (FGA) or their combinations, and the ninth group was a control group. In addition to the above combinations, four of the eight synchronized groups were given 5 mg follicle-stimulating hormone (FSH) and the remaining four groups were administered 300 IU equine chorionic gonadotrophin (eCG). Posttreatment follicular development was monitored until ovulation occurred using a real-time B-mode ultrasound scanner (Aloka, 500 SSD, Japan), with a 7.5-MHz transrectal linear probe. All the does from the synchronized groups that were given eCG exhibited oestrus while only 88.9% of the does synchronized with FSH showed estrus. The estrus response was observed to be the least among the does synchronized with PGF(2α) + FSH (33.3%) combination followed closely by the FGA + FSH (42.9%) combinations. It was observed that the combinations of FGA + PGF(2α) + FSH resulted in increased percentage of estrus response, duration of estrus, and ovulation. The number of follicles was higher (P < 0.05) in FSH-synchronized groups than the eCG-synchronized groups. It was concluded that the best estrus synchronization protocol in goats is the FGA + eCG with or without PGF(2α). However, the PGF(2α) + FGA + FSH method of estrus synchronization is the most promising combination for further development as a better alternative to estrus synchronization with eCG in does.
authors.affiliation: Faculty of Veterinary Medicine, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia.
authors.forename: Muhammad Modu
authors.initials: MM
authors.lastname: Bukar
authors.forename: Rosnina
authors.initials: R
authors.lastname: Yusoff
authors.forename: Abd Wahid
authors.initials: AW
authors.lastname: Haron
authors.forename: Gurmeet Kaur
authors.initials: GK
authors.lastname: Dhaliwal
authors.forename: Mohd Azam Goriman
authors.initials: MA
authors.lastname: Khan
authors.forename: Mohammed Ariff
authors.initials: MA
authors.lastname: Omar
mesh_terms: D000818:Animals; D006063:Chorionic Gonadotropin / Q000008:administration & dosage; D015237:Dinoprost / Q000008:administration & dosage*; D004338:Drug Combinations; D004971:Estrus / Q000187:drug effects*; D004973:Estrus Synchronization / Q000379:methods*; D005260:Female; D003425:Flurogestone Acetate / Q000008:administration & dosage*; D005640:Follicle Stimulating Hormone / Q000008:administration & dosage*; D006041:Goats; D006064:Gonadotropins, Equine / Q000008:administration & dosage*; D006854:Hydrocortisone / Q000097:blood; D006080:Ovarian Follicle / Q000000981:diagnostic imaging / Q000187:drug effects* / Q000254:growth & development; D013312:Stress, Physiological; D014329:Tropical Climate; D014463:Ultrasonography
chemical_list: D006063:Chorionic Gonadotropin; D004338:Drug Combinations; D006064:Gonadotropins, Equine; D005640:Follicle Stimulating Hormone; D015237:Dinoprost; D006854:Hydrocortisone; D003425:Flurogestone Acetate