title: Antireflux surgery in the proton pump inhibitor era.
abstract: Although proton pump inhibitors (PPIs) are now the first-line treatment for gastroesophageal reflux disease (GERD), surgery still has several specific indications. We review the current treatment of GERD and discuss how antireflux surgery fits into the overall scheme.
authors.affiliation: Center for Esophageal Diseases and Swallowing, Department of Medicine, Division of Gastroenterology, University of North Carolina School of Medicine, Chapel Hill, NC 27599-7080, USA. wbulsiewicz@gmail.com
authors.forename: William J
authors.initials: WJ
authors.lastname: Bulsiewicz
authors.forename: Ryan D
authors.initials: RD
authors.lastname: Madanick
mesh_terms: D001471:Barrett Esophagus / Q000601:surgery; D003371:Cough / Q000209:etiology; D050782:Esophageal pH Monitoring; D004942:Esophagitis, Peptic / Q000601:surgery; D005764:Gastroesophageal Reflux / Q000150:complications / Q000188:drug therapy / Q000601:surgery*; D006356:Heartburn / Q000209:etiology / Q000628:therapy; D006801:Humans; D007827:Laryngitis / Q000209:etiology; D057045:Laryngopharyngeal Reflux / Q000188:drug therapy / Q000601:surgery*; D054328:Proton Pump Inhibitors / Q000627:therapeutic use*
chemical_list: D054328:Proton Pump Inhibitors