title: Two laboratory-confirmed cases of Japanese encephalitis imported to Germany by travelers returning from Southeast Asia.
abstract: Japanese encephalitis virus is the leading cause of encephalitis in Asia and parts of the Pacific. Despite the high number of symptomatic infections in endemic countries, clinical disease in travelers is rare. However, an increasing number of imported infections from popular holiday destinations in Southeast Asia have been recorded in the past few years, including serious disease courses in short-term travelers. Here we report two severe, non-fatal cases in tourists, who returned from a long-time stay in Thailand and a short-term trip to Bali, Indonesia, respectively. Recommendations for vaccination and pre-travel advice are discussed.
authors.affiliation: Institute of Hygiene and Microbiology, University of Würzburg, Josef-Schneider-Str. 2, 97080 Würzburg, Germany.
authors.forename: Dennis
authors.initials: D
authors.lastname: Tappe
authors.forename: Andrea
authors.initials: A
authors.lastname: Nemecek
authors.forename: Frauke
authors.initials: F
authors.lastname: Zipp
authors.forename: Petra
authors.initials: P
authors.lastname: Emmerich
authors.forename: Martin
authors.initials: M
authors.lastname: Gabriel
authors.forename: Stephan
authors.initials: S
authors.lastname: Günther
authors.forename: Gerhard
authors.initials: G
authors.lastname: Dobler
authors.forename: Jonas
authors.initials: J
authors.lastname: Schmidt-Chanasit
authors.forename: August
authors.initials: A
authors.lastname: Stich
mesh_terms: D000368:Aged; D000914:Antibodies, Viral / Q000097:blood / Q000134:cerebrospinal fluid; D004672:Encephalitis, Japanese / Q000175:diagnosis*; D005260:Female; D005858:Germany; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood / Q000134:cerebrospinal fluid; D007075:Immunoglobulin M / Q000097:blood / Q000134:cerebrospinal fluid; D007214:Indonesia; D008297:Male; D008875:Middle Aged; D013785:Thailand; D014195:Travel
chemical_list: D000914:Antibodies, Viral; D007074:Immunoglobulin G; D007075:Immunoglobulin M