title: Coincidence of HPV11-Positive Urethral Condyloma Acuminatum and HPV-Negative Multiple Bladder Papillomas in a Female.
abstract: Human papillomaviruses (HPVs) are associated with proliferative lesions in a variety of human epithelial types. A 38-year-old female presented with a diagnosis of urethral condyloma acuminatum. She underwent transurethral resection of the urethral condyloma. At that time, multiple (five) bladder tumors were simultaneously found and also removed by transurethral resection. Four of the bladder tumors were diagnosed as squamous papilloma, and the other was urothelial inverted papilloma. Postoperative course was uneventful. Genomic DNA was extracted from 10 μm thick sections of each bladder tumor as well as urethral condyloma. Then, 16 types of HPV DNA sequences were assessed with the PapiPlex method using genomic DNA samples extracted from each bladder tumor as well as urethral condyloma. HPV-11 was detected in DNA extracted from the urethral condyloma, while no HPV DNA sequences were positive in any of the genomic DNA samples extracted from the bladder tumors.
authors.affiliation: Department of Urology, Kanto Rosai Hospital, 1-1 Kizukisumiyoshi-cho, Nakahara-ku, Kawasaki 211-8510, Japan.
authors.forename: Natsuko
authors.initials: N
authors.lastname: Nakazaki
authors.forename: Masayoshi
authors.initials: M
authors.lastname: Zaitsu
authors.forename: Koji
authors.initials: K
authors.lastname: Mikami
authors.forename: Shunsuke
authors.initials: S
authors.lastname: Yui
authors.forename: Ayumi
authors.initials: A
authors.lastname: Kanatani
authors.forename: Takushi
authors.initials: T
authors.lastname: Nakatani
authors.forename: Akiko
authors.initials: A
authors.lastname: Ito
authors.forename: Yuta
authors.initials: Y
authors.lastname: Takeshima
authors.forename: Akiko
authors.initials: A
authors.lastname: Tonooka
authors.forename: Hideaki
authors.initials: H
authors.lastname: Oka
authors.forename: Tomoko
authors.initials: T
authors.lastname: Miki
authors.forename: Takumi
authors.initials: T
authors.lastname: Takeuchi