title: Copper in Alzheimer's disease: a meta-analysis of serum, plasma, and cerebrospinal fluid studies.
abstract: This contribution reviews and corrects data from our previous meta-analysis, which appeared in the Journal of Alzheimer's Disease in 2011 concerning the role of copper in Alzheimer's disease. We repeated the meta-analysis after excluding four of the five studies from our laboratory to avoid possible bias in the result. In addition, we included two studies on serum copper levels in Alzheimer's disease not previously considered. The results indicate higher levels of copper in Alzheimer's disease patients than in controls, confirming our previous conclusion.
authors.affiliation: Department of Neurology, Campus Biomedico University, Rome, Italy.
authors.forename: Mariacarla
authors.initials: M
authors.lastname: Ventriglia
authors.forename: Serena
authors.initials: S
authors.lastname: Bucossi
authors.forename: Valentina
authors.initials: V
authors.lastname: Panetta
authors.forename: Rosanna
authors.initials: R
authors.lastname: Squitti
mesh_terms: D000544:Alzheimer Disease / Q000097:blood* / Q000134:cerebrospinal fluid* / Q000175:diagnosis; D015415:Biomarkers / Q000097:blood / Q000134:cerebrospinal fluid; D003300:Copper / Q000097:blood* / Q000134:cerebrospinal fluid*; D006801:Humans
chemical_list: D015415:Biomarkers; D003300:Copper