title: Regioselective enzymatic carboxylation of phenols and hydroxystyrene derivatives.
abstract: The enzymatic carboxylation of phenol and styrene derivatives using (de)carboxylases in carbonate buffer proceeded in a highly regioselective fashion: Benzoic acid (de)carboxylases selectively formed o-hydroxybenzoic acid derivatives, phenolic acid (de)carboxylases selectively acted at the β-carbon atom of styrenes forming (E)-cinnamic acids.
authors.affiliation: Austrian Centre of Industrial Biotechnology, University of Graz, Heinrichstrasse 28, A-8010 Graz, Austria.
authors.forename: Christiane
authors.initials: C
authors.lastname: Wuensch
authors.forename: Silvia M
authors.initials: SM
authors.lastname: Glueck
authors.forename: Johannes
authors.initials: J
authors.lastname: Gross
authors.forename: Dominik
authors.initials: D
authors.lastname: Koszelewski
authors.forename: Markus
authors.initials: M
authors.lastname: Schober
authors.forename: Kurt
authors.initials: K
authors.lastname: Faber
mesh_terms: D002262:Carboxy-Lyases / Q000378:metabolism*; D002934:Cinnamates / Q000138:chemical synthesis* / Q000737:chemistry; D020650:Combinatorial Chemistry Techniques; D062385:Hydroxybenzoates / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D010636:Phenols / Q000737:chemistry*; D013237:Stereoisomerism; D013343:Styrenes / Q000737:chemistry*
chemical_list: D002934:Cinnamates; D062385:Hydroxybenzoates; D010636:Phenols; D013343:Styrenes; C029010:cinnamic acid; D002262:Carboxy-Lyases