title: Reaction of a copper(II)-nitrosyl complex with hydrogen peroxide: putative formation of a copper(I)-peroxynitrite intermediate.
abstract: The reaction of a Cu(II)-nitrosyl complex (1) with hydrogen peroxide at -20 °C in acetonitrile results in the formation of the corresponding Cu(I)-peroxynitrite intermediate. The reduction of the Cu(II) center was monitored by UV-visible spectroscopic studies. Formation of the peroxynitrite intermediate has been confirmed by its characteristic phenol ring nitration reaction as well as isolation of corresponding Cu(I)-nitrate (2). On air oxidation, 2 resulted in the corresponding Cu(II)-nitrate (3). Thus, these results demonstrate a possible decomposition pathway for H(2)O(2) and NO through the formation of a peroxynitrite intermediate in biological systems.
authors.affiliation: Department of Chemistry, Indian Institute of Technology Guwahati, Guwahati, Assam 781039, India.
authors.forename: Apurba
authors.initials: A
authors.lastname: Kalita
authors.forename: Pankaj
authors.initials: P
authors.lastname: Kumar
authors.forename: Biplab
authors.initials: B
authors.lastname: Mondal
mesh_terms: D056831:Coordination Complexes / Q000737:chemistry*; D003300:Copper / Q000737:chemistry*; D006861:Hydrogen Peroxide / Q000737:chemistry*; D008968:Molecular Conformation; D010084:Oxidation-Reduction; D030421:Peroxynitrous Acid / Q000737:chemistry*; D013056:Spectrophotometry, Ultraviolet
chemical_list: D056831:Coordination Complexes; D030421:Peroxynitrous Acid; D003300:Copper; D006861:Hydrogen Peroxide