title: Comparison of quality of recovery from anaesthesia in cats induced with propofol or alfaxalone.
abstract: OBJECTIVE
  To assess the quality and length of recovery from anaesthesia induced with either propofol or alfaxalone and maintained with isoflurane, in cats undergoing short procedures in private veterinary practice.
  
  
  METHODS
  Prospective, blinded, randomized study.
  
  
  METHODS
  Ninety-three healthy mixed breed cats.
  
  
  METHODS
  After premedication with intramuscular acepromazine (0.05 mg kg(-1)) and buprenorphine (0.01 mg kg(-1)), cats were randomly allocated to receive either propofol (Group P) or alfaxalone (Group A) for induction of anaesthesia. Following endotracheal intubation, anaesthesia was maintained with isoflurane vaporized in oxygen. The quality of induction, physiological parameters throughout anaesthesia and the duration of both surgery and anaesthesia were recorded. The level of ambient noise, recovery times, number of attempts to stand, reaction of the cat to touch 15 minutes after extubation, and other relevant characteristics of the recovery period were noted and a video recording of the recovery was made. The videos were assessed by a second, blinded anaesthetist, using simple descriptive and visual analogue scales.
  
  
  RESULTS
  No statistically significant differences between groups with respect to preoperative data, premedication, surgery, anaesthesia and recovery times and scores were observed. There was a statistically significant difference in the number of patients paddling and trembling on recovery in Group A (p = 0.032) even though there was no statistically significant difference in the level of ambient noise in the recovery ward or in the overall quality of recovery.
  
  
  CONCLUSIONS
  Both propofol and alfaxalone provide good recovery characteristics in premedicated cats undergoing short procedures in clinical settings. Alfaxalone induction was associated with more episodes of paddling and trembling during recovery.
  
  
  CONCLUSIONS
  Both agents would appear appropriate for induction of anaesthesia in cats for short procedures.
authors.affiliation: Department of Veterinary Clinical Sciences, Royal Veterinary College, Hatfield, Hertfordshire, UK. alessandra.mathis@willows.uk.net
authors.forename: Alessandra
authors.initials: A
authors.lastname: Mathis
authors.forename: Rui
authors.initials: R
authors.lastname: Pinelas
authors.forename: David C
authors.initials: DC
authors.lastname: Brodbelt
authors.forename: Hatim I K
authors.initials: HI
authors.lastname: Alibhai
mesh_terms: D000762:Anesthesia Recovery Period; D000777:Anesthetics / Q000494:pharmacology; D000818:Animals; D002371:Cat Diseases / Q000139:chemically induced*; D002415:Cats; D005260:Female; D008297:Male; D011183:Postoperative Complications / Q000139:chemically induced / Q000662:veterinary*; D011277:Pregnanediones / Q000494:pharmacology*; D015742:Propofol / Q000494:pharmacology*
chemical_list: D000777:Anesthetics; D011277:Pregnanediones; C006477:alphaxalone; D015742:Propofol