title: [Refractory thrombotic thrombocytopenic purpura revealing an epiglotis neoplasia].
abstract: Thrombotic thrombocytopenic purpura (TTP) is a thrombotic microangiopathy with neurological disorder which incidence is relatively rare. Since the discovery of the ADAMTS 13 in 1996 and the changes in the treatment (plasma exchanges and rituximab), the prognosis of the TTP has considerably improved. We report the case of a 60-year-old man with a refractory TTP. The subsequent discovery of an epiglottis neoplasia and its treatment saved the patient.
authors.affiliation: Département d'anesthésie-réanimation, centre hospitalier Lyon sud, chemin du Grand-Revoyet, 69495 Pierre-Bénite, France. florent.baudin@chu-lyon.fr
authors.forename: F
authors.initials: F
authors.lastname: Baudin
authors.forename: P
authors.initials: P
authors.lastname: Guillot
authors.forename: B
authors.initials: B
authors.lastname: Bedock
authors.forename: P-L
authors.initials: PL
authors.lastname: Blanc
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D058846:Antibodies, Monoclonal, Murine-Derived / Q000627:therapeutic use; D000964:Antimetabolites, Antineoplastic / Q000008:administration & dosage; D000970:Antineoplastic Agents / Q000008:administration & dosage; D000972:Antineoplastic Agents, Phytogenic / Q000008:administration & dosage; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002294:Carcinoma, Squamous Cell / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy; D002945:Cisplatin / Q000008:administration & dosage; D000077143:Docetaxel; D004825:Epiglottis; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D007822:Laryngeal Neoplasms / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D010951:Plasma Exchange; D010956:Plasmapheresis; D010976:Platelet Count; D011697:Purpura, Thrombotic Thrombocytopenic / Q000150:complications* / Q000628:therapy; D000069283:Rituximab; D043823:Taxoids / Q000008:administration & dosage; D014805:Vitamin B 12 / Q000627:therapeutic use; D014815:Vitamins / Q000627:therapeutic use
chemical_list: D000305:Adrenal Cortex Hormones; D058846:Antibodies, Monoclonal, Murine-Derived; D000964:Antimetabolites, Antineoplastic; D000970:Antineoplastic Agents; D000972:Antineoplastic Agents, Phytogenic; D043823:Taxoids; D014815:Vitamins; D000077143:Docetaxel; D000069283:Rituximab; D014805:Vitamin B 12; D002945:Cisplatin; D005472:Fluorouracil