title: Four types of traditional Chinese medicine inducing epileptic seizures.
abstract: Traditional Chinese medicine has been used to treat disease in China for more than five thousand years. Over the last few decades it has been used increasingly in other countries as well. As its use has spread, interest in the adverse effects of traditional Chinese medicine, including epilepsy and epileptic seizures, has grown. To date, four types of traditional Chinese medicine have been found to induce epileptic seizures. In this review we will summarize the current knowledge about possible epileptogenic mechanisms of nux vomica, illicium henryi, betelnut and mulberry drawing on botanical, phytochemical, toxicological and animal studies.
authors.affiliation: Department of Neurology, The First Affiliated Hospital, Chongqing Medical University, Chongqing 400016, People's Republic of China.
authors.forename: Mengjiao
authors.initials: M
authors.lastname: Wu
authors.forename: Min
authors.initials: M
authors.lastname: Fang
authors.forename: Yida
authors.initials: Y
authors.lastname: Hu
authors.forename: Xuefeng
authors.initials: X
authors.lastname: Wang
mesh_terms: D000818:Animals; D001114:Areca / Q000009:adverse effects* / Q000737:chemistry; D002681:China; D004827:Epilepsy / Q000139:chemically induced*; D006801:Humans; D029523:Illicium / Q000009:adverse effects* / Q000737:chemistry; D008516:Medicine, Chinese Traditional / Q000009:adverse effects*; D031625:Morus / Q000009:adverse effects* / Q000737:chemistry; D031461:Strychnos nux-vomica / Q000009:adverse effects* / Q000737:chemistry