title: Pre-terminal renal insufficiency in a patient with enteric hyperoxaluria: effect of medical management on renal function.
abstract: Enteric hyperoxaluria causes tubular deposition calcium oxalate crystals and severe chronic interstitial nephritis. We describe a patient with pre-terminal renal failure due to oxalate nephropathy after ileal resection. Increased oral hydration, low oxalate diet, and oral calcium carbonate and potassium citrate supplements resulted in a significant improvement of renal function. During the three-year follow-up, urinary oxalate concentration was repeatedly reduced below the crystallization threshold and serum creatinine decreased from 4.5 to 1.7 mg/dL. This case illustrates the benefit of combining and optimizing dietary and medical management in enteric hyperoxaluria, even in patients with advanced chronic kidney disease.
authors.affiliation: Dept. of Nephrology, Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel, Belgium. lissa.pipeleers@uzbrussel.be
authors.forename: L
authors.initials: L
authors.lastname: Pipeleers
authors.forename: K M
authors.initials: KM
authors.lastname: Wissing
authors.forename: Y
authors.initials: Y
authors.lastname: Pirson
authors.forename: J P
authors.initials: JP
authors.lastname: Cosyns
authors.forename: C
authors.initials: C
authors.lastname: Geers
authors.forename: C
authors.initials: C
authors.lastname: Tielemans
mesh_terms: D000368:Aged; D005260:Female; D006801:Humans; D006959:Hyperoxaluria / Q000150:complications / Q000175:diagnosis / Q000628:therapy*; D051437:Renal Insufficiency / Q000175:diagnosis / Q000209:etiology / Q000628:therapy*