title: Effects of antidepressants and mood stabilizers on serum levels of adiponectin.
abstract: The effect of antidepressants and mood stabilizers on serum levels of adiponectin was investigated. Fluvoxamine (30 and 50 mg/kg/day) or lithium (40 and 60 mg/kg/day) was dissolved in distilled water and administered orally to rats every day for 4 weeks. Fluvoxamine (50 mg/kg/day) alone significantly elevated the serum level of adiponectin, but no significant difference was found between other drug-treated groups and the control group. This difference of these drugs' effectiveness on serum adiponectin might contribute to their differences of action mechanisms and therapeutic effects.
authors.affiliation: Department of Neuropsychiatry, Faculty of Medical Sciences, University of Fukui, Fukui, Japan. omata@u-fukui.ac.jp.
authors.forename: Naoto
authors.initials: N
authors.lastname: Omata
authors.forename: Tetsuhito
authors.initials: T
authors.lastname: Murata
authors.forename: Kosuke
authors.initials: K
authors.lastname: Narita
authors.forename: Nobuyuki
authors.initials: N
authors.lastname: Maruoka
authors.forename: Hironori
authors.initials: H
authors.lastname: Mitsuya
authors.forename: Kayo
authors.initials: K
authors.lastname: Mita
authors.forename: Takefumi
authors.initials: T
authors.lastname: Nishimoto
authors.forename: Makoto
authors.initials: M
authors.lastname: Sato
authors.forename: Yuji
authors.initials: Y
authors.lastname: Wada
mesh_terms: D052242:Adiponectin / Q000097:blood; D000818:Animals; D000928:Antidepressive Agents / Q000627:therapeutic use; D008094:Lithium
chemical_list: D052242:Adiponectin; D000928:Antidepressive Agents; D008094:Lithium