title: Comparison of tear osmolarity and ocular comfort between daily disposable contact lenses: hilafilcon B hydrogel versus narafilcon A silicone hydrogel.
abstract: The aim of this study was to evaluate tear osmolarity and ocular comfort with two different types of hydrogel daily disposable lenses. The right eyes of 15 first-time contact lens users were included in this prospective study. All eyes wore hilafilcon B silicone hydrogel contact lenses for 8 h (group 1). After 1 week without contact lenses, all eyes wore narafilcon A silicone hydrogel contact lenses for 8 h (group 2). Tear osmolarity measurement was performed before and after 4 and 8 h of each contact lens wear. Ocular comfort was assessed after 4 and 8 h of each contact lens wear. In group 1, the mean baseline, 4- and 8-h tear osmolarity values were 293 ± 10.57, 303.00 ± 10.5 mOsm/L (p = 0.023), and 295.0 ± 1.4 mOsm/L (p > 0.05), respectively. In group 2, the mean baseline, 4- and 8-h tear osmolarity values were 294 ± 13.65, 300.9 ± 11.3 mOsm/L (p = 0.007), and 298.80 ± 7.2 mOsm/L (p > 0.05), respectively. In group 1, the mean comfort score was 7.20 ± 0.45 and 8.60 ± 0.45 at 4 and 8 h, respectively (p = 0.038). In group 2, the mean comfort score significantly decreased from 9.80 ± 0.45 to 7.80 ± 0.84 at 4 h (p = 0.039). Both hydrogel and silicone hydrogel daily disposable contact lenses elevated tear osmolarity during 8 h of contact lens wear. The increase in tear osmolarity with both contact lenses was below the cut-off value for dry eye and was not associated with ocular comfort.
authors.affiliation: 2nd Department of Ophthalmology, Ankara Ataturk Training and Research Hospital, Bilkent, Ankara, Turkey. osarac2002@yahoo.com
authors.forename: Ozge
authors.initials: O
authors.lastname: Sarac
authors.forename: Canan
authors.initials: C
authors.lastname: Gurdal
authors.forename: Basak
authors.initials: B
authors.lastname: Bostancı-Ceran
authors.forename: Izzet
authors.initials: I
authors.lastname: Can
mesh_terms: D000328:Adult; D003263:Contact Lenses, Hydrophilic; D004209:Disposable Equipment; D005260:Female; D006801:Humans; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate; D008297:Male; D008875:Middle Aged; D009994:Osmolar Concentration; D017060:Patient Satisfaction; D011446:Prospective Studies; D012826:Silicone Elastomers; D013666:Tears / Q000737:chemistry*; D055815:Young Adult
chemical_list: D012826:Silicone Elastomers; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate