title: Autoimmune pancreatitis with histologically proven lymphoplasmacytic sclerosing pancreatitis with granulocytic epithelial lesions.
abstract: Recent histological and clinical studies have suggested the existence of 2 distinct types of autoimmune pancreatitis (AIP): type 1 AIP related to IgG4, exhibiting lymphoplasmacytic sclerosing pancreatitis (LPSP), and type 2 AIP related to granulocyte epithelial lesions (GELs), exhibiting idiopathic duct-centric chronic pancreatitis (IDCP). We herein present a case of type 1 AIP with histologically proven LPSP with GELs. This patient had neither serum IgG4 elevation nor MPD narrowing. In this case, the clinically and histologically atypical findings for type 1 AIP are intriguing.
authors.affiliation: The Third Department of Internal Medicine, Division of Gastroenterology and Hepatology, Kansai Medical University, Japan. ikeurat@takii.kmu.ac.jp
authors.forename: Tsukasa
authors.initials: T
authors.lastname: Ikeura
authors.forename: Makoto
authors.initials: M
authors.lastname: Takaoka
authors.forename: Kazushige
authors.initials: K
authors.lastname: Uchida
authors.forename: Masaaki
authors.initials: M
authors.lastname: Shimatani
authors.forename: Hideaki
authors.initials: H
authors.lastname: Miyoshi
authors.forename: Takeo
authors.initials: T
authors.lastname: Kusuda
authors.forename: Akiko
authors.initials: A
authors.lastname: Kurishima
authors.forename: Yuri
authors.initials: Y
authors.lastname: Fukui
authors.forename: Kimi
authors.initials: K
authors.lastname: Sumimoto
authors.forename: Sohei
authors.initials: S
authors.lastname: Satoi
authors.forename: Chisato
authors.initials: C
authors.lastname: Ohe
authors.forename: Yoshiko
authors.initials: Y
authors.lastname: Uemura
authors.forename: A-Hon
authors.initials: AH
authors.lastname: Kwon
authors.forename: Kazuichi
authors.initials: K
authors.lastname: Okazaki
mesh_terms: D001327:Autoimmune Diseases / Q000276:immunology* / Q000473:pathology*; D002760:Cholangiopancreatography, Endoscopic Retrograde; D049448:Cholangiopancreatography, Magnetic Resonance; D006098:Granulocytes / Q000473:pathology; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D008297:Male; D008875:Middle Aged; D010183:Pancreatic Ducts / Q000473:pathology; D010195:Pancreatitis / Q000145:classification / Q000276:immunology* / Q000473:pathology*; D049268:Positron-Emission Tomography; D012598:Sclerosis; D014057:Tomography, X-Ray Computed
chemical_list: D007074:Immunoglobulin G