title: TAFI made stickier.
abstract: Bleeding in hemophilia is the result of factor VIII/IX deficiency with corresponding reduced thrombin production and enhanced fibrinolysis secondary to lower thrombin activatable fibrinolysis inhibitor (TAFI) production. Factor replacement is the cornerstone of hemophilia treatment but is often not possible in developing countries.
authors.affiliation: Bloodcenter of Wisconsin, USA.
authors.forename: Thomas
authors.initials: T
authors.lastname: Abshire
mesh_terms: D000818:Animals; D001777:Blood Coagulation / Q000187:drug effects*; D004283:Dog Diseases / Q000097:blood*; D006467:Hemophilia A / Q000097:blood*; D006801:Humans; D018179:Receptors, Thrombin; D011994:Recombinant Proteins / Q000494:pharmacology*
chemical_list: D018179:Receptors, Thrombin; D011994:Recombinant Proteins; C558438:solulin protein