title: Circulating microRNAs: next-generation biomarkers for early lung cancer detection.
abstract: Early diagnosis of lung cancer by low-dose computed tomography is an effective strategy to reduce cancer mortality in high-risk individuals. However, recruitment of at-risk individuals with asymptomatic lung cancer still remains challenging. We developed a minimal invasive serum test, based on the detection of circulating microRNAs, which can identify at-risk individuals with asymptomatic early stage non-small cell lung carcinomas with 80% accuracy.
authors.affiliation: Department of Experimental Oncology, European Institute of Oncology, Milan, Italy.
authors.forename: F
authors.initials: F
authors.lastname: Bianchi
authors.forename: F
authors.initials: F
authors.lastname: Nicassio
authors.forename: G
authors.initials: G
authors.lastname: Veronesi
authors.forename: P P
authors.initials: PP
authors.lastname: di Fiore