title: Self condensation of enamines mediated by acetylation. A novel approach to 1-(azol-5-yl)-(1E,3Z)-butadiene-4-N,N-dimethylamines.
abstract: Novel self-condensation of 3-(azol-5-yl)-1,1-dimethylenamines has been found to form new C-C bonds leading to 2,4-(1,2,3-triazole-1,2,3-thiadiazole-3-phenylisothiazole)-(1E,3Z)-5-yl-butadiene-1-amines. The discovered reaction represents a new example of C-H functionalization in unsaturated systems and can serve an efficient synthetic approach to rational design of new 2,4-(diazole-5-yl)-dieneamines.
authors.affiliation: TOS. Lab. of Ural Federal University named after first President of Russia B. N. Eltsin, 19 Mira Str., 620002 Yekaterinburg, Russia.
authors.forename: Yuri
authors.initials: Y
authors.lastname: Shafran
authors.forename: Yuri
authors.initials: Y
authors.lastname: Rozin
authors.forename: Tetyana
authors.initials: T
authors.lastname: Beryozkina
authors.forename: Sergei
authors.initials: S
authors.lastname: Zhidovinov
authors.forename: Oleg
authors.initials: O
authors.lastname: Eltsov
authors.forename: Julia
authors.initials: J
authors.lastname: Subbotina
authors.forename: Johann
authors.initials: J
authors.lastname: Leban
authors.forename: Rashida
authors.initials: R
authors.lastname: Novikova
authors.forename: Vasiliy
authors.initials: V
authors.lastname: Bakulev
mesh_terms: D000107:Acetylation; D001713:Biphenyl Compounds / Q000737:chemistry*; D003959:Diamines / Q000138:chemical synthesis / Q000737:chemistry*; D015195:Drug Design; D007093:Imidazoles / Q000737:chemistry*; D013379:Substrate Specificity
chemical_list: D001713:Biphenyl Compounds; D003959:Diamines; D007093:Imidazoles