title: Predicting resting energy expenditure in boys with Duchenne muscular dystrophy.
abstract: BACKGROUND
  Understanding how best to predict energy needs in Duchenne muscular dystrophy (DMD) is fundamental to weight management in clinical practice; however there is a large gap in the literature regarding information on the most appropriate method. We aimed to ascertain the most valid predictive equation that can be used to predict REE in steroid treated ambulatory boys with DMD.
  
  
  METHODS
  REE was measured in 9 boys with DMD using indirect calorimetry after an overnight fast. REE was predicted using five different equations, based on height, weight, or body composition variables.
  
  
  RESULTS
  Mean measured REE was 5.4 (SD 0.4) MJ/day. The inclusion of fat free mass in the prediction equation provided no benefit over body weight. The exclusion of height, when compared with weight alone, improved predictive performance, as seen with the Schofield equations, in which a minimal bias and root means squared error is seen.
  
  
  CONCLUSIONS
  The most accurate and precise equation was the Schofield weight equation (Bias -0.2 MJ, 95% CI: -1.3-0.9 MJ), which can easily be calculated in a clinical setting and provides a solid foundation from which clinicians can establish energy requirements to support nutritional management in boys with DMD.
authors.affiliation: Children's Nutrition Research Centre, Discipline of Paediatrics and Child Health, The University of Queensland, Royal Children's Hospital, Herston, QLD 4029, Australia.
authors.forename: Sarah A
authors.initials: SA
authors.lastname: Elliott
authors.forename: Zoe E
authors.initials: ZE
authors.lastname: Davidson
authors.forename: Peter S W
authors.initials: PS
authors.lastname: Davies
authors.forename: Helen
authors.initials: H
authors.lastname: Truby
mesh_terms: D000465:Algorithms; D000886:Anthropometry; D001823:Body Composition / Q000502:physiology; D001835:Body Weight / Q000502:physiology; D002153:Calorimetry, Indirect; D002648:Child; D002675:Child, Preschool; D004734:Energy Metabolism / Q000502:physiology*; D006801:Humans; D016018:Least-Squares Analysis; D008297:Male; D020388:Muscular Dystrophy, Duchenne / Q000503:physiopathology*; D012146:Rest / Q000502:physiology