title: Photoselective vaporization versus transurethral resection of the prostate for benign prostatic hyperplasia: a meta-analysis.
abstract: OBJECTIVE
  To determine whether photoselective vaporization has advantages over transurethral resection of the prostate (TURP) in terms of effectiveness and safety for treatment of patients with benign prostatic hyperplasia.
  
  
  METHODS
  MEDLINE, EMBASE, and the Cochrane Controlled Trial Register were searched for randomized controlled trials. The risk ratio, mean difference, and their corresponding 95% confidence intervals were calculated for dichotomous and continuous outcomes, respectively. Risk of bias of enrolled trials was assessed according to Cochrane Handbook.
  
  
  RESULTS
  A total of five trials were enrolled. There was no significant difference in the International Prostate Symptom Score and maximum flow rate between photoselective vaporization and TURP at 6-, 12-, and 24-month follow-up. Photoselective vaporization was associated with significantly lower risk of capsule perforation, transurethral resection syndrome, and clot retention, significantly lower transfusion requirements, a shorter catheterization time, and a shorter length of hospital stay. TURP was associated with a shorter operative time and a lower risk of reoperation. In addition, there was no difference in risk of acute urinary retention and urethral/bladder neck sclerosis between photoselective vaporization and TURP.
  
  
  CONCLUSIONS
  Photoselective vaporization and TURP provide comparable improvements in functional results, including International Prostate Symptom Score and maximum flow rate at 6-, 12-, and 24-month follow-up. Photoselective vaporization offers advantages over TURP in terms of intraoperative safety; however, TURP is found to have a shorter operative time and lower reoperative risk.
authors.affiliation: Department of First Clinical Medical College, Nanjing Medical University, Nanjing, Jiangsu, China.
authors.forename: Xiaolong
authors.initials: X
authors.lastname: Zhang
authors.forename: Jiang
authors.initials: J
authors.lastname: Geng
authors.forename: Junhua
authors.initials: J
authors.lastname: Zheng
authors.forename: Bo
authors.initials: B
authors.lastname: Peng
authors.forename: Jianping
authors.initials: J
authors.lastname: Che
authors.forename: Chang
authors.initials: C
authors.lastname: Liang
mesh_terms: D000368:Aged; D002404:Catheterization; D006801:Humans; D053685:Laser Therapy / Q000009:adverse effects / Q000379:methods*; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D061646:Operative Time; D011183:Postoperative Complications / Q000209:etiology; D011470:Prostatic Hyperplasia / Q000601:surgery*; D017594:Publication Bias; D016032:Randomized Controlled Trials as Topic; D020728:Transurethral Resection of Prostate / Q000009:adverse effects / Q000379:methods*