title: Serum anti-müllerian hormone, follicle stimulating hormone and antral follicle count measurement cannot predict pregnancy rates in IVF/ICSI cycles.
abstract: OBJECTIVE
  To investigate whether serum anti-müllerian hormone (AMH), follicle stimulating hormone (FSH), or antral follicle count (AFC) are predictive for clinical pregnancy in in vitro fertilization (IVF) patients.
  
  
  METHODS
  Serum AMH, inhibin B, FSH, luteinizing hormone (LH), estradiol (E2), prolactin, and thyroid stimulating hormone (TSH) levels and AFC of 189 women under 40 years of age were investigated. Pregnant and non-pregnant women were compared.
  
  
  RESULTS
  Forty-seven (24.8 %) clinical pregnancies were observed in 189 women. There was no significant difference in terms of mean age, duration of infertility, body mass index, AMH, LH, FSH, E2, TSH, Inhibin B, AFC and total oocyte number between women who did and who did not become pregnant. Additionally, there was no significant difference in clinical pregnancy rates between the quartiles of AMH, FSH and AFC. (P values were 0.668, 0.071, and 0.252, respectively.)
  
  
  CONCLUSIONS
  Serum AMH and FSH, and AFC cannot predict clinical pregnancy in IVF patients under 40; the pregnancy rate tends to increase as AMH increases, although this remains non-significant.
authors.affiliation: Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology, Istanbul University, Cerrahpasa School of Medicine, Istanbul, Turkey.
authors.forename: Sezai
authors.initials: S
authors.lastname: Sahmay
authors.forename: Gökhan
authors.initials: G
authors.lastname: Demirayak
authors.forename: Onur
authors.initials: O
authors.lastname: Guralp
authors.forename: Pelin
authors.initials: P
authors.lastname: Ocal
authors.forename: Levent M
authors.initials: LM
authors.lastname: Senturk
authors.forename: Engin
authors.initials: E
authors.lastname: Oral
authors.forename: Tulay
authors.initials: T
authors.lastname: Irez
mesh_terms: D000328:Adult; D054304:Anti-Mullerian Hormone / Q000097:blood*; D004958:Estradiol / Q000097:blood; D005260:Female; D005307:Fertilization in Vitro; D005640:Follicle Stimulating Hormone / Q000097:blood*; D006801:Humans; D007265:Inhibins / Q000097:blood; D007986:Luteinizing Hormone / Q000097:blood; D006080:Ovarian Follicle / Q000502:physiology*; D011247:Pregnancy; D018873:Pregnancy Rate; D011388:Prolactin / Q000097:blood; D020554:Sperm Injections, Intracytoplasmic; D013972:Thyrotropin / Q000097:blood
chemical_list: C422364:inhibin B; D004958:Estradiol; D007265:Inhibins; D054304:Anti-Mullerian Hormone; D011388:Prolactin; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone; D013972:Thyrotropin