title: Highly biocompatible, hollow coordination polymer nanoparticles as cisplatin carriers for efficient intracellular drug delivery.
abstract: Highly biocompatible coordination polymer (Prussian Blue) nanoparticles (LC(50) > 1000 μg mL(-1)) with a hollow interior and a microporous framework (denoted as HPB) are utilized as an anticancer drug (i.e. cisplatin) capsule for chemotherapy of bladder cancer T24 cells.
authors.affiliation: Department of Chemical Engineering, National Taiwan University, No. 1, Sec. 4, Roosevelt Road, Taipei 10617, Taiwan.
authors.forename: Hong-Yuan
authors.initials: HY
authors.lastname: Lian
authors.forename: Ming
authors.initials: M
authors.lastname: Hu
authors.forename: Chia-Hung
authors.initials: CH
authors.lastname: Liu
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Yamauchi
authors.forename: Kevin C-W
authors.initials: KC
authors.lastname: Wu
mesh_terms: D000970:Antineoplastic Agents / Q000633:toxicity; D017209:Apoptosis / Q000187:drug effects; D001672:Biocompatible Materials / Q000737:chemistry; D045744:Cell Line, Tumor; D002945:Cisplatin / Q000633:toxicity; D004337:Drug Carriers / Q000737:chemistry*; D005295:Ferrocyanides / Q000737:chemistry; D006801:Humans; D053758:Nanoparticles / Q000737:chemistry*; D011108:Polymers / Q000737:chemistry*; D001749:Urinary Bladder Neoplasms / Q000473:pathology
chemical_list: D000970:Antineoplastic Agents; D001672:Biocompatible Materials; D004337:Drug Carriers; D005295:Ferrocyanides; D011108:Polymers; D002945:Cisplatin; C000170:ferric ferrocyanide