title: [Fabrication of silver ordered nanoarrays SERS-active substrates and their applications in bladder cancer cells detection].
abstract: Highly ordered silver nanopore and nanocap arrays, which were used as surface-enhanced Raman scattering active (SERS-active) substrates, were fabricated by electron-beam evaporating silver on the surface of porous layer and barrier layer of porous anodic alumina (PAA) membranes, respectively. The SERS characteristics of the SERS-active substrates were tested with bladder cancer cells as molecular probe. The results indicated that both the SERS-active substrates displayed a strong SERS enhancement effect. The silver nanocap ordered arrays SERS-active substrate displayed not only higher SERS and fluorescence quenching effect, but also no interferential spectrum related with oxalate impurity remaining in PAA membranes, and therefore can result in the high quality Raman spectroscopy of bladder cancer cells.
authors.affiliation: School of Science, Xi'an Jiaotong University, Xi'an 710049, China. yoyossc@163.com
authors.forename: You
authors.initials: Y
authors.lastname: Liu
authors.forename: Li-qing
authors.initials: LQ
authors.lastname: Huang
authors.forename: Jun
authors.initials: J
authors.lastname: Wang
authors.forename: Hui-min
authors.initials: HM
authors.lastname: Tong
authors.forename: Lin
authors.initials: L
authors.lastname: Yuan
authors.forename: Li-hua
authors.initials: LH
authors.lastname: Zhao
authors.forename: Wei-wei
authors.initials: WW
authors.lastname: Zhang
authors.forename: Leiz
authors.initials: L
authors.lastname: Wang
authors.forename: Jian
authors.initials: J
authors.lastname: Zhu
mesh_terms: D000537:Aluminum Oxide; D006801:Humans; D016062:Porosity; D012834:Silver; D013059:Spectrum Analysis, Raman; D013499:Surface Properties; D001749:Urinary Bladder Neoplasms
chemical_list: D012834:Silver; D000537:Aluminum Oxide