title: Automatic CPAP performance in patients with sleep apnea plus COPD.
abstract: BACKGROUND
  Automatic CPAP devices have demonstrated good results in obtaining optimal fixed CPAP pressure to eliminate respiratory events in patients with sleep apnea-hypopnea syndrome (SAHS). However, automatic CPAP has not been fully studied in patients with COPD plus SAHS.
  
  
  OBJECTIVE
  To analyse the performance of an automatic CPAP in severe COPD patients compared with SAHS patients with no associated co-morbidity.
  
  
  METHODS
  We compared 10 consecutive patients with SAHS and no associated co-morbidity and 10 patients with SAHS plus severe COPD who required CPAP titration. Automatic CPAP performance was studied during full-night PSG. Inadequate pressure increase periods, absence of pressure increases in reaction to respiratory events, air leak periods, and pressure behaviour in the face of erratic breathing periods were analysed.
  
  
  RESULTS
  The SAHS patients without co-morbidities vs. SAHS plus COPD patients presented: mean sleep efficiency, 80.2 (11.5)% vs. 76.5 (12.1)%; residual AHI, 6.3 (5.2) vs. 5.1 (7.7); residual CT90, 1 (3)% vs. 14 (1)%. The device´s performance demonstrates a mean of 1.2 (1.5) vs. 1.3 (1.2) periods of inadequate pressure increases; absence of pressure increases in reaction to respiratory events, 4.1 (5.4) vs. 0.6 (0.7) times; periods of air leaks, 1.3 (3.8) vs. 13.9 (11.7); mean optimal pressure, 9.1 (1.4) vs. 9.0 (1.9) cm H(2)O.
  
  
  CONCLUSIONS
  Titration with automatic CPAP could be as effective in patients with SAHS plus severe COPD as in patients with SAHS without COPD. However, the presence of more leakages must be taken into account.
authors.affiliation: Sleep Laboratory, Servei de Pneumologia i Al.lèrgia Respiratòria, Hospital Clinic-IDIBAPS, Barcelona, Spain.
authors.forename: Arnoldo
authors.initials: A
authors.lastname: Guerrero
authors.forename: J M
authors.initials: JM
authors.lastname: Montserrat
authors.forename: Ramon
authors.initials: R
authors.lastname: Farre
authors.forename: Fernando
authors.initials: F
authors.lastname: Masa
authors.forename: Joaquín
authors.initials: J
authors.lastname: Duran
authors.forename: Cristina
authors.initials: C
authors.lastname: Embid
mesh_terms: D000368:Aged; D045422:Continuous Positive Airway Pressure / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D017286:Polysomnography; D029424:Pulmonary Disease, Chronic Obstructive / Q000150:complications*; D020181:Sleep Apnea, Obstructive / Q000150:complications / Q000628:therapy*; D016896:Treatment Outcome