title: [Clinical study of Fuzheng Yiliu Recipe combined with microwave ablation on hepatocellular carcinoma].
abstract: OBJECTIVE
  To explore the clinical value of Fuzheng Yiliu Recipe (FYR) combined with microwave ablation on hepatocellular carcinoma.
  
  
  METHODS
  Sixty patients with hepatocellular carcinoma were randomly assigned to the control group and the treatment group according to the random digit table, 30 in each group. Patients in the control group received microwave ablation therapy, while those in the treatment group received FYR three days after microwave ablation. The therapeutic course was 6 months. By the end of the treatment, the short-term objective therapeutic efficacy, the liver function, the hepatic fibrosis index, the cellular immune function were statistically analyzed between the two groups.
  
  
  RESULTS
  The indices of the liver function, the hepatic fibrosis, and the cellular immune function were more significantly improved in the treatment group than in the control group (P < 0.05). The CD4+ level and the ratio of CD4+/CD8+ of the treatment group were remarkably higher than those of the control group (40.38 +/- 12.47 vs 28. 19 +/- 6.59, 1.49 +/- 0.41 vs 1.22 +/- 0.31). The tubercle recurrence rate of the treatment group (14.0%, 7/50) was significantly lower than that of the control group (33.3%, 15/45) after 6 months of treatment (P < 0.05).
  
  
  CONCLUSIONS
  FYR combined with microwave ablation could elevate the therapeutic efficacy, enhance the patients' immunity, improve the liver function and the hepatic fibrosis degree.
authors.affiliation: Department of Ultrasound, Second People's Hospital Affiliated to Fujian University of Traditional Chinese Medicine, Fuzhou.
authors.forename: Hong-Jia
authors.initials: HJ
authors.lastname: Zhao
authors.forename: Jian
authors.initials: J
authors.lastname: Du
authors.forename: Xi
authors.initials: X
authors.lastname: Chen
mesh_terms: D055011:Ablation Techniques; D006528:Carcinoma, Hepatocellular / Q000628:therapy*; D003131:Combined Modality Therapy; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D055048:Integrative Medicine; D008113:Liver Neoplasms / Q000628:therapy*; D008297:Male; D008872:Microwaves / Q000627:therapeutic use*; D008875:Middle Aged; D008517:Phytotherapy
chemical_list: D004365:Drugs, Chinese Herbal; C533482:fuzheng yiliu