title: [Surgical treatment of discogenic low back pain by minimally invasive transforaminal lumbar interbody fusion combined with unilateral pedicle screw fixation].
abstract: OBJECTIVE
  To investigate the effectiveness of surgical treatment for discogenic low back pain (DLBP) by minimally invasive transforaminal lumbar interbody fusion (TLIF) combined with unilateral pedicle screw fixation (UPSF).
  
  
  METHODS
  Between March 2006 and July 2009, 57 patients with single-level DLBP were treated by minimally invasive TLIF combined with UPSF, including 27 males and 30 females with an average age of 45.6 years (range, 38-61 years) and a disease duration of 3.8 years (range, 9 months to 11 years). The involved segments included L2, 3 in 2 cases, L3, 4 in 5 cases, L4, 5 in 29 cases, and L5, S1 in 21 cases. The operative time, incision length, intraoperative blood loss, postoperative drainage volume, hospitalization times, fusion rate, and complications were observed. The effectiveness were evaluated through Oswestry disability index (ODI) and visual analogue score (VAS), and the operative outcomes were compared in different groups classified according to various pressures of the contrast medium and sensitivities to disc block after inducing consistent pain.
  
  
  RESULTS
  The operation time, incision length, blood loss, postoperative drainage volume, and hospitalization times were (84.6 +/- 37.4) minutes, (3.4 +/- 0.6) cm, (132.5 +/- 23.2) mL, (58.7 +/- 21.4) mL, and (6.5 +/- 0.8) days, respectively. All patients were followed up 2 years and 2 months to 5 years and 4 months (mean, 3.2 years). At last follow-up, ODI and VAS scores were significantly improved when compared with preoperative scores (P < 0.05). The effectiveness according to ODI were excellent in 27 cases, good in 22 cases, fair in 6 cases, and poor in 2 cases, with an excellent and good rate of 86.0%. All patients acquired strong interbody fusion. At last follow-up according to ODI and VAS scores, better results were found in patients of low-pressure sensitive group and high-sensitive disc block group (P < 0.05).
  
  
  CONCLUSIONS
  Minimally invasive TLIF combined with UPSF is reliable for DLBP with minimal surgical trauma, less paravertebral tissue injury, and fewer complications, but the indications for operation must be strictly followed. Patients being sensitive to low-pressure or high-sensitive to disc block can achieve better surgical results.
authors.affiliation: Department of Spine Surgery, Fifth Affiliated Hospital of Guangxi Medical University/Liuzhou People's Hospital, Liuzhou Guangxi 545006, PR China.
authors.forename: Bowei
authors.initials: B
authors.lastname: Liang
authors.forename: Jinmin
authors.initials: J
authors.lastname: Zhao
authors.forename: Ningning
authors.initials: N
authors.lastname: Li
authors.forename: Zhaohui
authors.initials: Z
authors.lastname: Hu
authors.forename: Hongzhi
authors.initials: H
authors.lastname: Sun
mesh_terms: D000328:Adult; D001863:Bone Screws; D005260:Female; D006801:Humans; D016268:Internal Fixators; D007405:Intervertebral Disc Displacement / Q000150:complications / Q000601:surgery; D017116:Low Back Pain / Q000209:etiology / Q000601:surgery*; D008159:Lumbar Vertebrae; D008297:Male; D008875:Middle Aged; D019060:Minimally Invasive Surgical Procedures; D013123:Spinal Fusion / Q000379:methods