title: A rigid disc for protection of exposed blood vessels during negative pressure wound therapy.
abstract: BACKGROUND
  There are increasing reports of serious complications and deaths associated with negative pressure wound therapy (NPWT). Bleeding may occur when NPWT is applied to a wound with exposed blood vessels. Inserting a rigid disc in the wound may protect these structures. The authors examined the effects of rigid discs on wound bed tissue pressure and blood flow through a large blood vessel in the wound bed during NPWT.
  
  
  METHODS
  Wounds were created over the femoral artery in the groin of 8 pigs. Rigid discs were inserted. Wound bed pressures and arterial blood flow were measured during NPWT.
  
  
  RESULTS
  Pressure transduction to the wound bed was similar for control wounds and wounds with discs. Blood flow through the femoral artery decreased in control wounds. When a disc was inserted, the blood flow was restored.
  
  
  CONCLUSIONS
  NPWT causes hypoperfusion in the wound bed tissue, presumably as a result of mechanical deformation. The insertion of a rigid barrier alleviates this effect and restores blood flow.
authors.affiliation: Lund University and Skåne University Hospital, Lund, Sweden.
authors.forename: Erik
authors.initials: E
authors.lastname: Anesäter
authors.forename: Ola
authors.initials: O
authors.lastname: Borgquist
authors.forename: Christian
authors.initials: C
authors.lastname: Torbrand
authors.forename: K Markus
authors.initials: KM
authors.lastname: Roupé
authors.forename: Richard
authors.initials: R
authors.lastname: Ingemansson
authors.forename: Sandra
authors.initials: S
authors.lastname: Lindstedt
authors.forename: Malin
authors.initials: M
authors.lastname: Malmsjö
mesh_terms: D000704:Analysis of Variance; D000818:Animals; D005260:Female; D005263:Femoral Artery / Q000502:physiology; D006614:Hindlimb / Q000098:blood supply / Q000293:injuries / Q000601:surgery; D008297:Male; D054843:Negative-Pressure Wound Therapy / Q000295:instrumentation* / Q000379:methods; D011312:Pressure; D012039:Regional Blood Flow / Q000502:physiology*; D013552:Swine; D014945:Wound Healing / Q000502:physiology*