title: [Clinical trial of sexual dysfunctions in male patients with pituitary adenomas].
abstract: OBJECTIVE
  To explore the clinical features and related factors of sexual dysfunctions in male patients with pituitary adenomas.
  
  
  METHODS
  The questionnaires of sexual functions were collected from 86 male patients with pituitary adenomas. We examined the clinical features of sexual dysfunctions and analyzed the correlations between sexual behaviors and age, tumor type, invasiveness, tumor size, serum levels of prolactin (PRL) and testosterone.
  
  
  RESULTS
  The incidence of sexual dysfunctions was 80.2% (69/86). Sexual dysfunctions were found in 84.6% (66/78) of the patients with functioning pituitary adenomas and 37.5% (3/8) of those with non-functioning pituitary adenoma respectively. In the PRL group, the incidence of erectile dysfunctions was 92.1% (35/38) and it was higher than those in the FSH (follicle-stimulating hormone) and GH (growth hormone) groups (P < 0.05). In the FSH group, the incidence of reduced sexual desire was 78.3% (18/23). In the GH group, the incidence of erectile dysfunctions was 70.6% (12/17) and the incidence of reduced sexual desire or ejaculation dysfunction was lower than that of the PRL/FSH group (P < 0.05).
  
  
  CONCLUSIONS
  The incidence of sexual dysfunctions is quite high in males with pituitary adenomas, especially for those with functioning pituitary adenomas. The clinical features of sexual dysfunctions vary in different types of functioning pituitary adenoma. The incidence of erectile dysfunctions is the highest in the PRL group. Pathological type of pituitary tumors is a major risk factor of sexual dysfunctions.
authors.affiliation: Department of Urology, Fudan University, Shanghai, China.
authors.forename: Ren-yuan
authors.initials: RY
authors.lastname: Zhou
authors.forename: Guo-min
authors.initials: GM
authors.lastname: Wang
authors.forename: Yue-hui
authors.initials: YH
authors.lastname: Zhang
authors.forename: Guo-wei
authors.initials: GW
authors.lastname: Shi
authors.forename: Jia-yang
authors.initials: JY
authors.lastname: He
authors.forename: Wei-zhong
authors.initials: WZ
authors.lastname: Jiang
authors.forename: Shi-qi
authors.initials: SQ
authors.lastname: Li
mesh_terms: D000328:Adult; D007172:Erectile Dysfunction / Q000453:epidemiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010911:Pituitary Neoplasms / Q000453:epidemiology* / Q000503:physiopathology; D012189:Retrospective Studies; D055815:Young Adult