title: [Evaluation on the effect of comprehensive control strategy of schistosomiasis with emphasis on infection source control in Anhui province].
abstract: OBJECTIVE
  To evaluate the effect of comprehensive control strategy of schistosomiasis with emphasis on infection source control in Anhui province.
  
  
  METHODS
  Forty endemic villages in Guichi district, Chizhou city, Anhui province were selected as national pilot villages in the years from 2006 to 2008, and another 10 provincial pilot villages were respectively selected from 10 highly endemic villages in 7 cities in 2007. The comprehensive infection source control measures, including "replace cattle with machines", "raise livestock in pens", "improve the sanitary toilets", "supply safe water " and so on were carried out among the above pilot villages. At the end of 2008, 13 national pilot villages and 6 provincial pilot villages were selected to investigate the popularity of schistosomiasis, and the effect of the comprehensive control strategy in those villages were compared.
  
  
  RESULTS
  After implementing the comprehensive control strategy, the infectious rate of schistosomiasis in national pilot villages decreased from 4.57% (487/10 659) to 1.76% (147/8370), with the reduction rate at 61.49%, whose difference showed statistical significance (χ(2) = 115.16, P < 0.01); and the density of infected snails decreased from 0.0067/0.1 m(2) to 0.0008/0.1 m(2), the infectious rate of snails decreased from 0.28% to 0.04%, whose reduction rates were 88.06% and 85.71% respectively. While as to the provincial pilot villages, the infectious rate of schistosomiasis decreased from 1.27% (54/4254) to 0.21% (14/6592), with the reduction rate at 83.46%, whose difference showed statistical significance (χ(2) = 94.57, P < 0.01); and the density of infected snails decreased from 0.0025/0.1 m(2) to 0.0003/0.1 m(2), the infection rate of snails decreased from 0.13% to 0.05%, whose reduction rates were 88.00% and 61.54% respectively.
  
  
  CONCLUSIONS
  The comprehensive control strategy with emphasis on infection source control implemented in marshland and lake regions can effectively control the transmission of schistosomiasis.
authors.affiliation: Anhui Institute of Schistosomiasis Control, Hefei 230061, China.
authors.forename: Zhi-Guo
authors.initials: ZG
authors.lastname: Cao
authors.forename: Tian-Ping
authors.initials: TP
authors.lastname: Wang
authors.forename: Jia-Chang
authors.initials: JC
authors.lastname: He
authors.forename: Shi-Qing
authors.initials: SQ
authors.lastname: Zhang
authors.forename: Geng-Xin
authors.initials: GX
authors.lastname: Chen
authors.forename: Gong-Hua
authors.initials: GH
authors.lastname: Zhang
authors.forename: Hao
authors.initials: H
authors.lastname: Wang
authors.forename: Zong-Gui
authors.initials: ZG
authors.lastname: He
mesh_terms: D000818:Animals; D002681:China / Q000453:epidemiology; D004197:Disease Reservoirs / Q000469:parasitology; D006801:Humans; D017053:Infection Control / Q000379:methods*; D058751:Livestock; D010865:Pilot Projects; D012423:Rural Health; D012552:Schistosomiasis / Q000453:epidemiology* / Q000469:parasitology / Q000517:prevention & control*; D012908:Snails / Q000469:parasitology*