title: The cortical representation of simple mathematical expressions.
abstract: Written mathematical notation conveys, in a compact visual form, the nested functional relations among abstract concepts such as operators, numbers or sets. Is the comprehension of mathematical expressions derived from the human capacity for processing the recursive structure of language? Or does algebraic processing rely only on a language-independent network, jointly involving the visual system for parsing the string of mathematical symbols and the intraparietal system for representing numbers and operators? We tested these competing hypotheses by scanning mathematically trained adults while they viewed simple strings ranging from randomly arranged characters to mathematical expressions with up to three levels of nested parentheses. Syntactic effects were observed in behavior and in brain activation measured with functional magnetic resonance imaging (fMRI) and magneto-encephalography (MEG). Bilateral occipito-temporal cortices and right parietal and precentral cortices appeared as the primary nodes for mathematical syntax. MEG estimated that a mathematical expression could be parsed by posterior visual regions in less than 180 ms. Nevertheless, a small increase in activation with increasing expression complexity was observed in linguistic regions of interest, including the left inferior frontal gyrus and the posterior superior temporal sulcus. We suggest that mathematical syntax, although arising historically from language competence, becomes "compiled" into visuo-spatial areas in well-trained mathematics students.
authors.affiliation: INSERM, U992, Cognitive Neuroimaging Unit, F-91191 Gif/Yvette, France. mmasaki1974@gmail.com
authors.forename: Masaki
authors.initials: M
authors.lastname: Maruyama
authors.forename: Christophe
authors.initials: C
authors.lastname: Pallier
authors.forename: Antoinette
authors.initials: A
authors.lastname: Jobert
authors.forename: Mariano
authors.initials: M
authors.lastname: Sigman
authors.forename: Stanislas
authors.initials: S
authors.lastname: Dehaene
mesh_terms: D000328:Adult; D001921:Brain / Q000502:physiology*; D001931:Brain Mapping; D032882:Comprehension / Q000502:physiology*; D005260:Female; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D008279:Magnetic Resonance Imaging; D015225:Magnetoencephalography; D008297:Male; D055641:Mathematical Concepts; D010775:Photic Stimulation; D012815:Signal Processing, Computer-Assisted; D055815:Young Adult