title: Individually customized implants for laryngoplasty--are they possible?
abstract: OBJECTIVE
  To standardize the design of individually fitted implants based on computed tomographic (CT) images for use in medialization laryngoplasty without intraoperative voice monitoring.
  
  
  METHODS
  Prospective tomographic and anatomical experimental study of 10 human cadaveric larynges.
  
  
  METHODS
  CT scans of 10 excised human larynges were analyzed to define the shape and size of ideal implants for medialization laryngoplasty. Silicone implants were designed according to CT parameters and used in simulated laryngoplasties in the laryngeal specimens. The efficacy of each implant in providing adequate medialization of the vocal fold was evaluated.
  
  
  RESULTS
  Diverse shapes and sizes of implants were obtained, reflecting variations in laryngeal anatomy. The implants enabled regular medialization of the entire extent of the free border of the vocal fold, including its posterior aspect. Medialization was considered adequate in all cases.
  
  
  CONCLUSIONS
  This method proved to be a simple and efficient way to design individualized implants for medialization laryngoplasty, regardless of the size and shape of the larynx.
  
  
  METHODS
  Not available.
authors.affiliation: Department of Otolaryngology, University of São Paulo, São Paulo, Brazil. frizzarini@gmail.com
authors.forename: Ronaldo
authors.initials: R
authors.lastname: Frizzarini
authors.forename: Eloísa M M S
authors.initials: EM
authors.lastname: Gebrim
authors.forename: Rui
authors.initials: R
authors.lastname: Imamura
authors.forename: Domingos H
authors.initials: DH
authors.lastname: Tsuji
authors.forename: Raquel A
authors.initials: RA
authors.lastname: Moyses
authors.forename: Luiz U
authors.initials: LU
authors.lastname: Sennes
mesh_terms: D000368:Aged; D002102:Cadaver; D017076:Computer-Aided Design; D005260:Female; D006801:Humans; D058753:Laryngoplasty / Q000295:instrumentation*; D007830:Larynx / Q000033:anatomy & histology / Q000000981:diagnostic imaging / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011474:Prosthesis Design; D019919:Prosthesis Implantation / Q000295:instrumentation*; D012828:Silicones; D014057:Tomography, X-Ray Computed; D014827:Vocal Cords / Q000033:anatomy & histology / Q000000981:diagnostic imaging / Q000601:surgery*
chemical_list: D012828:Silicones