title: Evaluation of the correlation between self-report and electronic monitoring of adherence to hypertension therapy.
abstract: Blood pressure (BP) control remains sub-optimal all over the world. Medication adherence is an important determinant of BP control. None of the available methods for measuring medication adherence is currently regarded as a universal consensus gold standard. In this study, we evaluated the correlation between self-report (Morisky's Medication Adherence Self-assessment Scale) and electronic (eCap) methods of medication adherence assessment. The self-report measure was administered at study entry while electronic compliance data was collected prospectively. Almost all (97.4%) of enrolled patients completed the study. Medication adherence scores ranged from 0 to 100% (69.33, ± 27.57) and 6.6-100% (66.92 ± 22.59) for Morisky's scale and eCap, respectively (Wilcoxon rank sum test, p = 0.253). Modal class interval for adherence scores were 61-80% (n = 28, 37.3%) and 81-100% (n = 23, 30.7%) for the eCap and Morisky's scale respectively. Overall, a weak correlation was found between the two methods (r = 0.056). The weak correlation was also maintained in subgroup analysis defined by attainment of BP control (r = 0.109 vs 0.0009), age (range r = -0.53 to 0.067), sex (0.009 to 0.151), level of education (-0.217 to 0.276), and Mini Mental State Examination score (-0.107 to 0.258). Our findings suggest that these methods are not equivalent in the evaluation of medication adherence.
authors.affiliation: Department of Family Medicine, Lagos State University Teaching Hospital, Ikeja, Lagos, Nigeria.
authors.forename: Adedokun
authors.initials: A
authors.lastname: Ayoade
authors.forename: Idris
authors.initials: I
authors.lastname: Oladipo
mesh_terms: D000328:Adult; D000368:Aged; D000959:Antihypertensive Agents / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D008297:Male; D016347:Medical Records Systems, Computerized; D055118:Medication Adherence; D008875:Middle Aged; D010349:Patient Compliance; D057566:Self Report; D012647:Self-Assessment; D011795:Surveys and Questionnaires
chemical_list: D000959:Antihypertensive Agents