title: Combining modular ligation and supramolecular self-assembly for the construction of star-shaped macromolecules.
abstract: A well-defined random copolymer of styrene (S) and chloromethylstyrene (CMS) featuring lateral chlorine moieties with an alkyne terminal group is prepared (P(S-co-CMS), M(n) = 5500 Da, PDI = 1.13). The chloromethyl groups are converted into Hamilton wedge (HW) entities (P(S-co-HWS), M(n) = 6200 Da, PDI = 1.13). The P(S-co-HWS) polymer is subsequently ligated with tetrakis(4-azidophenyl)methane to give HW-functional star-shaped macromolecules (P(S-co-HWS))(4), M(n) = 25,100 Da, PDI = 1.08). Supramolecular star-shaped copolymers are then prepared via self-assembly between the HW-functionalized four-arm star-shaped macromolecules (P(S-co-HW))(4) and cyanuric acid (CA) end-functionalized PS (PS-CA, M(n) = 3700 Da, PDI = 1.04), CA end-functionalized poly(methyl methacrylate) (PMMA-CA, M(n) = 8500 Da, PDI = 1.13) and CA end-functionalized polyethylene glycol (PEG-CA, M(n) = 1700 Da, PDI = 1.05). The self-assembly is monitored by (1)H NMR spectroscopy and light scattering analyses.
authors.affiliation: Preparative Macromolecular Chemistry, Center for Functional Nanostructures (CFN), Karlsruhe Institute of Technology (KIT), Engesserstr. 18, 76128 Karlsruhe, Germany.
authors.forename: Ozcan
authors.initials: O
authors.lastname: Altintas
authors.forename: Thierry
authors.initials: T
authors.lastname: Muller
authors.forename: Elise
authors.initials: E
authors.lastname: Lejeune
authors.forename: Oliver
authors.initials: O
authors.lastname: Plietzsch
authors.forename: Stefan
authors.initials: S
authors.lastname: Bräse
authors.forename: Christopher
authors.initials: C
authors.lastname: Barner-Kowollik
mesh_terms: D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D015394:Molecular Structure; D011137:Polystyrenes / Q000138:chemical synthesis* / Q000737:chemistry*
chemical_list: D011137:Polystyrenes; C426943:poly(p-chloromethylstyrene)