title: Remission in early rheumatoid arthritis -- a comparison of new ACR/EULAR remission criteria to established criteria.
abstract: OBJECTIVE
  To describe the frequency of remission in an early rheumatoid arthritis (ERA) cohort.
  
  
  METHODS
  The frequency of remission was evaluated, based on 8 definitions including the Boolean-based American College of Rheumatology/European League Against Rheumatism (ACR/EULAR) criteria.
  
  
  RESULTS
  Of 369 patients, remission at 12 months ranged from 18% according to the ACR/EULAR clinical trial criteria to 40% according to the 28-joint Disease Activity Score (DAS28) < 2.6. Higher tender joint count, swollen joint count, and physician global scores were seen for DAS28-based definitions, and patient global assessment (PtGA) scores were almost 5-fold higher for DAS28 remission.
  
  
  CONCLUSIONS
  Remission is achievable in ERA but its frequency differs according to the remission definition applied. Adoption of the new ACR/EULAR definition will limit the number classified as in remission, especially if the PtGA criteria are rated high for reasons other than inflammatory arthritis.
authors.affiliation: Division of Rheumatology, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada. bindee.kuriya@utoronto.ca
authors.forename: Bindee
authors.initials: B
authors.lastname: Kuriya
authors.forename: Ye
authors.initials: Y
authors.lastname: Sun
authors.forename: Gilles
authors.initials: G
authors.lastname: Boire
authors.forename: Boulos
authors.initials: B
authors.lastname: Haraoui
authors.forename: Carol
authors.initials: C
authors.lastname: Hitchon
authors.forename: Janet E
authors.initials: JE
authors.lastname: Pope
authors.forename: John C
authors.initials: JC
authors.lastname: Thorne
authors.forename: Edward C
authors.initials: EC
authors.lastname: Keystone
authors.forename: Vivian P
authors.initials: VP
authors.lastname: Bykerk
mesh_terms: D018501:Antirheumatic Agents / Q000627:therapeutic use*; D001172:Arthritis, Rheumatoid / Q000175:diagnosis* / Q000188:drug therapy* / Q000503:physiopathology; D015331:Cohort Studies; D018450:Disease Progression; D004359:Drug Therapy, Combination; D042241:Early Diagnosis; D005260:Female; D006801:Humans; D007596:Joints / Q000187:drug effects / Q000473:pathology / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D017063:Outcome Assessment, Health Care / Q000379:methods*; D012074:Remission Induction; D015203:Reproducibility of Results
chemical_list: D018501:Antirheumatic Agents