title: Adapting federated cyberinfrastructure for shared data collection facilities in structural biology.
abstract: Early stage experimental data in structural biology is generally unmaintained and inaccessible to the public. It is increasingly believed that this data, which forms the basis for each macromolecular structure discovered by this field, must be archived and, in due course, published. Furthermore, the widespread use of shared scientific facilities such as synchrotron beamlines complicates the issue of data storage, access and movement, as does the increase of remote users. This work describes a prototype system that adapts existing federated cyberinfrastructure technology and techniques to significantly improve the operational environment for users and administrators of synchrotron data collection facilities used in structural biology. This is achieved through software from the Virtual Data Toolkit and Globus, bringing together federated users and facilities from the Stanford Synchrotron Radiation Lightsource, the Advanced Photon Source, the Open Science Grid, the SBGrid Consortium and Harvard Medical School. The performance and experience with the prototype provide a model for data management at shared scientific facilities.
authors.affiliation: Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA.
authors.forename: Ian
authors.initials: I
authors.lastname: Stokes-Rees
authors.forename: Ian
authors.initials: I
authors.lastname: Levesque
authors.forename: Frank V
authors.initials: FV
authors.lastname: Murphy
authors.forename: Wei
authors.initials: W
authors.lastname: Yang
authors.forename: Ashley
authors.initials: A
authors.lastname: Deacon
authors.forename: Piotr
authors.initials: P
authors.lastname: Sliz
mesh_terms: D033181:Information Dissemination; D016247:Information Storage and Retrieval; D011506:Proteins / Q000737:chemistry*; D012984:Software; D017356:Synchrotrons; D014481:United States
chemical_list: D011506:Proteins