title: Bacteriology of the paranasal sinuses in pediatric cystic fibrosis patients.
abstract: OBJECTIVE
  To review the characteristic microbiology of the paranasal sinuses in patients with cystic fibrosis who undergo endoscopic sinus surgery. To examine the subtypes of organisms cultured from the maxillary sinuses and determine their sensitivity to antibiotic therapy.
  
  
  METHODS
  Retrospective chart review.
  
  
  METHODS
  Tertiary care children's hospital.
  
  
  METHODS
  Sinus cultures were obtained from 51 patients with cystic fibrosis during endoscopic sinus procedures between 2000 and 2004 at a tertiary care children's hospital. A retrospective chart review was undertaken to obtain culture and sensitivity data of the sinus contents.
  
  
  RESULTS
  The most common bacteria isolated was Staphylococcus aureus (71%), followed by Pseudomonas aeruginosa (PSA) (27%), Haemophilus influenzae (21%), Staphylococcus non-aureus (16%) and Streptococcus viridans (12%). Streptococcus pneumoniae and Moraxella catarrhalis were rarely isolated (2% and 0% respectively). Twenty-nine percent of the patients with cultures positive for PSA were of the mucoid variant. Only one patient had culture positive Escherichia coli. Antibiotic resistance among the more common organisms cultured from the sinus samples is also listed.
  
  
  CONCLUSIONS
  Staph. aureus is the most common isolate in the sinuses of this pediatric CF population followed by P. aeruginosa and H. influenzae. Although many isolates are pansensitive, some isolates are panresistant.
authors.affiliation: Department of Otolaryngology, OU Medical Center, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA. Paul-Digoy@ouhsc.edu
authors.forename: G Paul
authors.initials: GP
authors.lastname: Digoy
authors.forename: Joel D
authors.initials: JD
authors.lastname: Dunn
authors.forename: Julie A
authors.initials: JA
authors.lastname: Stoner
authors.forename: Alana
authors.initials: A
authors.lastname: Christie
authors.forename: Dwight T
authors.initials: DT
authors.lastname: Jones
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003550:Cystic Fibrosis / Q000382:microbiology*; D004724:Endoscopy; D006801:Humans; D007223:Infant; D008443:Maxillary Sinus / Q000382:microbiology* / Q000601:surgery*; D008826:Microbial Sensitivity Tests; D012189:Retrospective Studies