title: Management of Helicobacter pylori infection--the Maastricht IV/ Florence Consensus Report.
abstract: Management of Helicobacter pylori infection is evolving and in this 4th edition of the Maastricht consensus report aspects related to the clinical role of H pylori were looked at again in 2010. In the 4th Maastricht/Florence Consensus Conference 44 experts from 24 countries took active part and examined key clinical aspects in three subdivided workshops: (1) Indications and contraindications for diagnosis and treatment, focusing on dyspepsia, non-steroidal anti-inflammatory drugs or aspirin use, gastro-oesophageal reflux disease and extraintestinal manifestations of the infection. (2) Diagnostic tests and treatment of infection. (3) Prevention of gastric cancer and other complications. The results of the individual workshops were submitted to a final consensus voting to all participants. Recommendations are provided on the basis of the best current evidence and plausibility to guide doctors involved in the management of this infection associated with various clinical conditions.
authors.affiliation: Department of Gastroenterology, Hepatology and Infectious Diseases, Otto-von-Guericke University of Magdeburg, Magdeburg, Germany. peter.malfertheiner@med.ovgu.de
authors.forename: Peter
authors.initials: P
authors.lastname: Malfertheiner
authors.forename: Francis
authors.initials: F
authors.lastname: Megraud
authors.forename: Colm A
authors.initials: CA
authors.lastname: O'Morain
authors.forename: John
authors.initials: J
authors.lastname: Atherton
authors.forename: Anthony T R
authors.initials: AT
authors.lastname: Axon
authors.forename: Franco
authors.initials: F
authors.lastname: Bazzoli
authors.forename: Gian Franco
authors.initials: GF
authors.lastname: Gensini
authors.forename: Javier P
authors.initials: JP
authors.lastname: Gisbert
authors.forename: David Y
authors.initials: DY
authors.lastname: Graham
authors.forename: Theodore
authors.initials: T
authors.lastname: Rokkas
authors.forename: Emad M
authors.initials: EM
authors.lastname: El-Omar
authors.forename: Ernst J
authors.initials: EJ
authors.lastname: Kuipers
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D017291:Clarithromycin / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005764:Gastroesophageal Reflux / Q000382:microbiology; D005773:Gastroscopy; D016481:Helicobacter Infections / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy; D016480:Helicobacter pylori; D006801:Humans; D056692:Prebiotics; D019936:Probiotics; D054328:Proton Pump Inhibitors / Q000627:therapeutic use; D013274:Stomach Neoplasms / Q000382:microbiology / Q000517:prevention & control
chemical_list: D000900:Anti-Bacterial Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D056692:Prebiotics; D054328:Proton Pump Inhibitors; D017291:Clarithromycin