title: Lean mass predicts hip geometry and bone mineral density in chinese men and women and age comparisons of body composition.
abstract: Previous studies have suggested that changes in hip geometry increase the risk of hip fracture. The aim of this study was to identify whether body composition were associated with hip geometry or bone mineral density (BMD) in a large sample of Chinese people. A total of 2072 subjects aged 20-79 yr (including 700 males and 1372 females) were selected. The following measurements were taken: lumbar spine (L1-4); proximal femur BMD; lean mass (LM); fat mass (FM); and hip geometric parameters, including hip axis length (HAL), cross-sectional moment of inertia (CSMI), cross-sectional area (CSA), neck-shaft angle, and femur strength index (SI) by dual-energy X-ray absorptiometry. FM and LM were positively correlated with HAL, CSMI, and CSA, and negatively correlated with SI in both men and women. Multiple regression analysis showed that leg LM contributions to HAL, CSMI, and CSA variance were 12.6-37.6%. Compared with FM, LM was generally more strongly related to hip geometry and BMD in young and old men and women. Body composition was a good predictor for hip geometry parameter variation and BMD variation.
authors.affiliation: Department of Osteoporosis and Bone Disease, Metabolic Bone Disease and Genetic Research Unit, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.
authors.forename: Wei-Wei
authors.initials: WW
authors.lastname: Hu
authors.affiliation: Department of Osteoporosis and Bone Disease, Metabolic Bone Disease and Genetic Research Unit, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.
authors.forename: Hao
authors.initials: H
authors.lastname: Zhang
authors.affiliation: Department of Osteoporosis and Bone Disease, Metabolic Bone Disease and Genetic Research Unit, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.
authors.forename: Chun
authors.initials: C
authors.lastname: Wang
authors.affiliation: Department of Osteoporosis and Bone Disease, Metabolic Bone Disease and Genetic Research Unit, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.
authors.forename: Jie-Mei
authors.initials: JM
authors.lastname: Gu
authors.affiliation: Department of Osteoporosis and Bone Disease, Metabolic Bone Disease and Genetic Research Unit, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.
authors.forename: Hua
authors.initials: H
authors.lastname: Yue
authors.affiliation: Department of Osteoporosis and Bone Disease, Metabolic Bone Disease and Genetic Research Unit, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.
authors.forename: Yao-Hua
authors.initials: YH
authors.lastname: Ke
authors.affiliation: Department of Osteoporosis and Bone Disease, Metabolic Bone Disease and Genetic Research Unit, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.
authors.forename: Yun-Qiu
authors.initials: YQ
authors.lastname: Hu
authors.affiliation: Department of Osteoporosis and Bone Disease, Metabolic Bone Disease and Genetic Research Unit, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.
authors.forename: Wen-Zhen
authors.initials: WZ
authors.lastname: Fu
authors.affiliation: Department of Osteoporosis and Bone Disease, Metabolic Bone Disease and Genetic Research Unit, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.
authors.forename: Miao
authors.initials: M
authors.lastname: Li
authors.affiliation: Department of Osteoporosis and Bone Disease, Metabolic Bone Disease and Genetic Research Unit, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China. Electronic address: zzl2002@medmail.com.cn.
authors.forename: Zhen-Lin
authors.initials: ZL
authors.lastname: Zhang
mesh_terms: D015502:Absorptiometry, Photon / Q000379:methods*; D000328:Adult; D017677:Age Distribution; D000367:Age Factors; D000368:Aged; D001823:Body Composition; D015519:Bone Density; D002681:China / Q000453:epidemiology; D005260:Female; D006615:Hip / Q000000981:diagnostic imaging*; D006801:Humans; D008159:Lumbar Vertebrae / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000000981:diagnostic imaging / Q000453:epidemiology*; D015995:Prevalence; D012189:Retrospective Studies; D017678:Sex Distribution; D012737:Sex Factors; D055815:Young Adult