title: Prevalence of pharyngeal Chlamydia trachomatis and Neisseria gonorrhoeae among heterosexual men in Japan.
abstract: Pharyngeal chlamydial and gonococcal infections can occur as a consequence of oral sex, and they also can be transmitted from the pharynx to the genital tract of sex partners. There have been many reports on the prevalence of pharyngeal Chlamydia trachomatis and Neisseria gonorrhoeae in men who have sex with men; however, there have been few reports on the prevalence of these pathogens in the pharynges of heterosexual men. In this study, we determined the prevalence of pharyngeal C. trachomatis and N. gonorrhoeae in 42 heterosexual men diagnosed with urethritis. Pharyngeal swabs and first-voided urine specimens were tested using the Gen-Probe APTIMA Combo 2 transcription-mediated amplification assay. The prevalence of pharyngeal C. trachomatis and N. gonorrhoeae in patients with urethritis was 2.4 % (1/42) and 11.9 % (5/42), respectively. Among patients with either chlamydial or gonococcal urethritis, 9.1 % (1/11) and 25.0 % (5/20) had pharyngeal C. trachomatis or N. gonorrhoeae, respectively. Our results suggest that screening for pharyngeal colonization by N. gonorrhoeae and C. trachomatis using validated nucleic acid amplification tests should be performed in heterosexual men diagnosed with urethritis.
authors.affiliation: Department of Urology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kita-ku, Okayama, 700-8558, Japan. gmd17055@s.okadai.jp
authors.forename: Koichiro
authors.initials: K
authors.lastname: Wada
authors.forename: Shinya
authors.initials: S
authors.lastname: Uehara
authors.forename: Ritsuko
authors.initials: R
authors.lastname: Mitsuhata
authors.forename: Reiko
authors.initials: R
authors.lastname: Kariyama
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Nose
authors.forename: Shinichi
authors.initials: S
authors.lastname: Sako
authors.forename: Ayano
authors.initials: A
authors.lastname: Ishii
authors.forename: Toyohiko
authors.initials: T
authors.lastname: Watanabe
authors.forename: Akira
authors.initials: A
authors.lastname: Matsumoto
authors.forename: Koichi
authors.initials: K
authors.lastname: Monden
authors.forename: Satoru
authors.initials: S
authors.lastname: Uno
authors.forename: Tohru
authors.initials: T
authors.lastname: Araki
authors.forename: Hiromi
authors.initials: H
authors.lastname: Kumon
mesh_terms: D000293:Adolescent; D000328:Adult; D002690:Chlamydia Infections / Q000453:epidemiology* / Q000382:microbiology; D002692:Chlamydia trachomatis / Q000235:genetics / Q000302:isolation & purification*; D004269:DNA, Bacterial / Q000032:analysis / Q000235:genetics; D006069:Gonorrhea / Q000453:epidemiology* / Q000382:microbiology; D020010:Heterosexuality / Q000706:statistics & numerical data; D006801:Humans; D007564:Japan / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D009344:Neisseria gonorrhoeae / Q000235:genetics / Q000302:isolation & purification*; D010608:Pharyngeal Diseases / Q000453:epidemiology* / Q000382:microbiology; D010614:Pharynx / Q000382:microbiology; D015995:Prevalence; D012725:Sexual Behavior; D014521:Urethra / Q000382:microbiology; D014526:Urethritis / Q000150:complications / Q000453:epidemiology
chemical_list: D004269:DNA, Bacterial