title: Clinical outcome of umbilical artery catheter-related thrombosis - a cohort study.
abstract: OBJECTIVE
  To reveal the incidence of umbilical artery catheter-related thrombosis (UACRT), the associated risk factors and the natural history of clot formation and regression.
  
  
  METHODS
  A prospective cohort study. An umbilical artery catheter was inserted in 61 infants, who were evaluated and followed by serial duplex ultrasound studies for the development of UACRT, renal artery resistance index (RI) and clot resolution. Maternal and infant clinical variables were correlated with the characteristics of thrombi.
  
  
  RESULTS
  Nineteen infants developed UACRT, all resolved spontaneously without sequella; most had maximal length at the first evaluation. No correlation was found between the thrombus length and time to resolution. The RI did not differ between the infants with and without UACRT. After adjusting for possible confounding, catheter days was the only covariate associated with UACRT.
  
  
  CONCLUSIONS
  Asymptomatic UACRT in our cohort was a self-resolving disease; it was associated with catheter days and did not necessitate medical treatment.
authors.affiliation: Department of Neonatology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel. zivanit@hadassah.org.il
authors.forename: Z
authors.initials: Z
authors.lastname: Ergaz
authors.forename: N
authors.initials: N
authors.lastname: Simanovsky
authors.forename: K
authors.initials: K
authors.lastname: Rozovsky
authors.forename: S Abu
authors.initials: SA
authors.lastname: Leil
authors.forename: N
authors.initials: N
authors.lastname: Ofek-Shlomai
authors.forename: S
authors.initials: S
authors.lastname: Revel-Vilk
authors.forename: B
authors.initials: B
authors.lastname: Bar-Oz
mesh_terms: D000367:Age Factors; D002406:Catheterization, Peripheral / Q000009:adverse effects* / Q000379:methods; D015331:Cohort Studies; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007049:Iatrogenic Disease / Q000453:epidemiology*; D007231:Infant, Newborn; D015278:Intensive Care Units, Pediatric; D007557:Israel; D016015:Logistic Models; D008297:Male; D015995:Prevalence; D011446:Prospective Studies; D012075:Remission, Spontaneous; D018570:Risk Assessment; D012737:Sex Factors; D015996:Survival Rate; D013927:Thrombosis / Q000000981:diagnostic imaging / Q000453:epidemiology* / Q000209:etiology*; D016896:Treatment Outcome; D018615:Ultrasonography, Doppler, Color / Q000379:methods; D018616:Ultrasonography, Doppler, Duplex / Q000379:methods; D014469:Umbilical Arteries / Q000000981:diagnostic imaging* / Q000473:pathology