title: Susceptibility to etravirine of HIV type 1 subtype C isolates from nevirapine/efavirenz-experienced patients: comparative interpretation of ANRS and STANFORD algorithms.
abstract: Abstract   We analyzed subtype C HIV-1 isolates from patients at failure of a regimen including nevirapine or efavirenz for their susceptibility or resistance to etravirine according to the ANRS and STANFORD algorithms. Statistical analysis showed a consensus that more than 45% of these viral strains are potentially resistant to etravirine.
authors.affiliation: UMR 5234 CNRS and Laboratoire de Virologie (WHO accredited), University Hospital of Bordeaux, Bordeaux, France.
authors.forename: Delphine
authors.initials: D
authors.lastname: Anquetil
authors.forename: Alaka
authors.initials: A
authors.lastname: Deshpande
authors.forename: Drissa
authors.initials: D
authors.lastname: Zongo
authors.forename: Laurent
authors.initials: L
authors.lastname: Le Bihan
authors.forename: Patricia Recordon
authors.initials: PR
authors.lastname: Pinson
authors.forename: Herve J
authors.initials: HJ
authors.lastname: Fleury
mesh_terms: D000480:Alkynes; D000595:Amino Acid Sequence; D019380:Anti-HIV Agents / Q000494:pharmacology* / Q000627:therapeutic use; D048588:Benzoxazines / Q000627:therapeutic use; D003521:Cyclopropanes; D004279:DNA, Viral / Q000235:genetics; D024882:Drug Resistance, Viral; D015658:HIV Infections / Q000188:drug therapy / Q000821:virology*; D019427:HIV Integrase / Q000235:genetics*; D015497:HIV-1 / Q000187:drug effects / Q000235:genetics* / Q000302:isolation & purification; D006801:Humans; D008969:Molecular Sequence Data; D009073:Mozambique; D019829:Nevirapine / Q000627:therapeutic use; D009570:Nitriles; D011533:Proviruses / Q000235:genetics / Q000302:isolation & purification; D011724:Pyridazines / Q000494:pharmacology*; D011743:Pyrimidines; D017422:Sequence Analysis, DNA
chemical_list: D000480:Alkynes; D019380:Anti-HIV Agents; D048588:Benzoxazines; D003521:Cyclopropanes; D004279:DNA, Viral; D009570:Nitriles; D011724:Pyridazines; D011743:Pyrimidines; C451734:etravirine; D019829:Nevirapine; D019427:HIV Integrase; C098320:efavirenz