title: Contemporary use of adjunctive thrombectomy during primary percutaneous coronary intervention for ST-elevation myocardial infarction in the United States.
abstract: OBJECTIVE
  We sought to examine the contemporary use of thrombectomy during primary percutaneous coronary intervention (PCI) in the United States.
  
  
  BACKGROUND
  Adjunctive thrombectomy during primary PCI for patients with ST-segment elevation myocardial infarction (STEMI) has demonstrated mixed results. While earlier studies showed either unfavorable or neutral effects with rheolytic thrombectomy, recent clinical trials have shown benefits with manual or rheolytic thrombectomy when compared to PCI alone.
  
  
  METHODS
  We analyzed data from 122,449 patients undergoing primary PCI for STEMI from 1,181 centers reported to the CathPCI Registry® between July 2009 and December 2010. We used logistic regression analysis to examine factors associated with the use of manual and rheolytic thrombectomy.
  
  
  RESULTS
  Thrombectomy was performed in 23,195 patients (18.9%): 22,404 (18.3%) had manual thrombectomy and 791 (0.6%) had rheolytic thrombectomy. The use of manual thrombectomy increased over time (P < 0.05). The use of rheolytic thrombectomy did not change. There was significant variation in the use of thrombectomy across hospitals. The strongest predictors of manual versus no thrombectomy included TIMI 0/1 flow (odds ratio 1.69), younger age (OR 0.90 per 10 year increase), saphenous vein graft (OR 2.22), glycoprotein IIb/IIIa inhibitor (OR 1.34), single-vessel disease (OR 1.13), and year of admission (OR 1.20 per year; all P < 0.001). The strongest predictor of manual versus rheolytic thrombectomy was year of admission (OR 1.23, P < 0.001).
  
  
  CONCLUSIONS
  Our data show that thrombectomy is performed infrequently in the US during primary PCI for STEMI. There is significant variation in the use of thrombectomy across US hospitals.
authors.affiliation: Department of Medicine, Division of Cardiology, University of Utah, Salt Lake City, Utah, USA.
authors.forename: Theophilus E
authors.initials: TE
authors.lastname: Owan
authors.forename: Matthew T
authors.initials: MT
authors.lastname: Roe
authors.forename: John C
authors.initials: JC
authors.lastname: Messenger
authors.forename: David
authors.initials: D
authors.lastname: Dai
authors.forename: Andrew D
authors.initials: AD
authors.lastname: Michaels
mesh_terms: D000368:Aged; D016009:Chi-Square Distribution; D003328:Coronary Thrombosis / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy*; D005260:Female; D019538:Health Care Surveys; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D009203:Myocardial Infarction / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy*; D016017:Odds Ratio; D018579:Patient Selection; D062645:Percutaneous Coronary Intervention / Q000639:trends*; D010818:Practice Patterns, Physicians' / Q000639:trends*; D012042:Registries; D017131:Thrombectomy / Q000639:trends*; D013997:Time Factors; D014481:United States / Q000453:epidemiology