title: [Targeted chemotherapy for breast cancer: patients perception of the use of tumor gene profiling approaches to better adapt treatments].
abstract: The purpose of this review of the literature is to document how breast cancer patients perceive the use of tumor gene profiling approaches to better adapt treatments, and to identify the features of these approaches that may impact their clinical application. In general, the use of tumor genomic analysis was perceived by patients as an approach facilitating personalized medicine and received considerable support. Nevertheless, a number of confusions and worries about these practices were also identified. Improving the quality of provider/patient communications should enable patients to play a more active part in the decision-making about their treatment. This will ensure that those who agree to their tumor gene analysis have realistic expectations and sound deductions of the final result disclosure process.
authors.affiliation: Inserm UMR912, IRD, Marseille, France. isabelle.pellegrini@inserm.fr
authors.forename: Isabelle
authors.initials: I
authors.lastname: Pellegrini
authors.forename: Myrto
authors.initials: M
authors.lastname: Rapti
authors.forename: Jean-Marc
authors.initials: JM
authors.lastname: Extra
authors.forename: Anouk
authors.initials: A
authors.lastname: Petri-Cal
authors.forename: Themis
authors.initials: T
authors.lastname: Apostolidis
authors.forename: Jean-Marc
authors.initials: JM
authors.lastname: Ferrero
authors.forename: Thomas
authors.initials: T
authors.lastname: Bachelot
authors.forename: Patrice
authors.initials: P
authors.lastname: Viens
authors.forename: François
authors.initials: F
authors.lastname: Bertucci
authors.forename: Claire
authors.initials: C
authors.lastname: Julian-Reynier
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001943:Breast Neoplasms / Q000188:drug therapy* / Q000235:genetics / Q000523:psychology; D002277:Carcinoma / Q000188:drug therapy* / Q000235:genetics / Q000523:psychology; D003144:Communication Barriers; D005260:Female; D020869:Gene Expression Profiling / Q000706:statistics & numerical data; D006801:Humans; D025202:Molecular Diagnostic Techniques / Q000379:methods; D058990:Molecular Targeted Therapy / Q000706:statistics & numerical data*; D010465:Perception / Q000502:physiology*; D057285:Precision Medicine / Q000523:psychology*