title: Diagnostic yield of small bowel capsule endoscopy depends on the small bowel transit time.
abstract: OBJECTIVE
  To investigate whether the small bowel transit time (SBTT) influences the diagnostic yield of capsule endoscopy (CE).
  
  
  METHODS
  Six hundred and ninety-one consecutive CE procedures collected in a database were analyzed. SBTT and CE findings were recorded. A running mean for the SBTT was calculated and correlated to the diagnostic yield with a Spearman's correlation test. Subgroup analyses were performed for the various indications for the procedure.
  
  
  RESULTS
  There was a positive correlation between the diagnostic yield and SBTT (Spearman's rho 0.58, P < 0.01). Positive correlations between diagnostic yield and SBTT were found for the indication obscure gastrointestinal bleeding (r = 0.54, P < 0.01), for polyposis and carcinoid combined (r = 0.56, P < 0.01) and for the other indications (r = 0.90, P <0.01), but not for suspected Crohn's disease (r = -0.40).
  
  
  CONCLUSIONS
  The diagnostic yield in small bowel capsule endoscopy is positively correlated with the small bowel transit time. This is true for all indications except for suspected Crohn's disease.
authors.affiliation: Department of Gastroenterology and Hepatology, University Medical Center, University of Groningen, Groningen, The Netherlands.
authors.forename: Jessie
authors.initials: J
authors.lastname: Westerhof
authors.forename: Jan J
authors.initials: JJ
authors.lastname: Koornstra
authors.forename: Reinier A
authors.initials: RA
authors.lastname: Hoedemaker
authors.forename: Wim J
authors.initials: WJ
authors.lastname: Sluiter
authors.forename: Jan H
authors.initials: JH
authors.lastname: Kleibeuker
authors.forename: Rinse K
authors.initials: RK
authors.lastname: Weersma
mesh_terms: D053704:Capsule Endoscopy / Q000379:methods*; D005772:Gastrointestinal Transit / Q000502:physiology*; D006801:Humans; D007410:Intestinal Diseases / Q000175:diagnosis*; D007421:Intestine, Small / Q000473:pathology* / Q000502:physiology*; D013997:Time Factors