title: Effects of age (neonates and elderly) on skin barrier function.
abstract: Skin, together with its appendages, forms an organ with several defensive roles; among them it acts as a barrier, which is one of its very important protective functions. There has been increased interest in studying the effects of age on these functions. There are different intensities and timing involved in this process and also differences between men and women, all relating to skin structure. We review the current knowledge of the skin as a barrier in neonates and in the elderly in an attempt to explain the changes that occur with aging.
authors.affiliation: Sector of Dermatology and Post Graduation Course-HUCFF/UFRJ and School of Medicine, Federal University of Rio de Janeiro, Rua Dona Mariana 143/C-32, Rio de Janeiro 22280-020, Brazil. ramos.e.silva@dermato.med.br
authors.forename: Marcia
authors.initials: M
authors.lastname: Ramos-e-Silva
authors.forename: Juliana Catucci
authors.initials: JC
authors.lastname: Boza
authors.forename: Tania Ferreira
authors.initials: TF
authors.lastname: Cestari
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000502:physiology*; D004817:Epidermis / Q000502:physiology*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D010539:Permeability; D012879:Skin Physiological Phenomena