title: [Primary prophylaxis of early seizures after surgery of cerebral supratentorial tumors: Group for the Study of Functional-Sterotactic Neurosurgery of The Spain Society of Neurosurgery recommendations].
abstract: Our review of the literature is basically focused on the primary prophylaxis of early seizures after surgery of cerebral supratentorial tumors, with the aim of suggesting several recommendations in medical antiepileptic treatment to avoid this kind of seizures which occur immediately after surgery. In conclusion, it is recommended to provide criteria for prophylaxis of early seizures after surgery of cerebral supratentorial tumors. It́s recommended a one week treatment with antiepileptic drugs in patients who didńt have seizures jet, starting immediately after the surgical treatment. If seizures appear during progress of the disease, a large period treatment will be needed. Preferred antiepileptic treatment is intravenous and with a low interactions profile. Levetiracetam, followed by valproic acid seem to be most appropriated drugs due to their properties and protective effects, particularly for our patients requirements. These recommendations are considered a general proposal to effective clinical management of early seizures after surgery, not taking into account the single circumstances of our patients. Always, clinical features of the patients could modify even significantly these guides in the benefit of each patient.
authors.affiliation: Servicio de Neurocirugía, Hospital Carlos Haya, Málaga, España.
authors.forename: Miguel
authors.initials: M
authors.lastname: Domínguez-Páez
authors.forename: José Luis
authors.initials: JL
authors.lastname: Herranz-Fernández
authors.forename: Vicente
authors.initials: V
authors.lastname: Villanueva-Haba
authors.forename: Juan Carlos
authors.initials: JC
authors.lastname: Sánchez-Álvarez
authors.forename: Gonzalo
authors.initials: G
authors.lastname: Olivares-Granados
authors.forename: Rafael García-de
authors.initials: RG
authors.lastname: Sola
authors.forename: Julio
authors.initials: J
authors.lastname: Albisua-Sánchez
authors.forename: Miguel Ángel
authors.initials: MÁ
authors.lastname: Arráez-Sánchez
authors.forename: Bernardo
authors.initials: B
authors.lastname: Mosqueira-Centurión
authors.forename: Santiago
authors.initials: S
authors.lastname: Amaro-Cendón
authors.forename: Alicia
authors.initials: A
authors.lastname: Bollar-Zabala
authors.forename: Fernando
authors.initials: F
authors.lastname: Carceller-Benito
authors.forename: Julio
authors.initials: J
authors.lastname: Salazar-Hernández
authors.forename: Carlos
authors.initials: C
authors.lastname: Fernández-Carballal
authors.forename: Alfredo
authors.initials: A
authors.lastname: García-Allut
authors.forename: Eduardo
authors.initials: E
authors.lastname: García-Navarrete
authors.forename: Antonio
authors.initials: A
authors.lastname: Gutiérrez-Martín
authors.forename: José Luis
authors.initials: JL
authors.lastname: Lara-Cantalejo
authors.forename: Javier
authors.initials: J
authors.lastname: Márquez-Rivas
authors.forename: Bartolomé
authors.initials: B
authors.lastname: Oliver-Abadal
authors.forename: I Ñigo
authors.initials: IÑ
authors.lastname: Pomposo-Gaztelu
authors.forename: Angel
authors.initials: A
authors.lastname: Prieto-González
authors.forename: Jordi
authors.initials: J
authors.lastname: Rumiá-Arboix
authors.forename: Enrique
authors.initials: E
authors.lastname: Urculo-Bareño
mesh_terms: D000927:Anticonvulsants / Q000627:therapeutic use; D006801:Humans; D009493:Neurosurgery; D012640:Seizures; D013030:Spain; D015173:Supratentorial Neoplasms
chemical_list: D000927:Anticonvulsants