title: Mortality and pituitary disease.
abstract: Outcome data from large series confirm increased mortality of patients with pituitary tumours, predominantly due to vascular disease. Control of cortisol secretion and growth hormone (GH) hypersecretion (together with cardiovascular risk factor reduction) is key in the normalisation of mortality rates in patients with Cushing's disease and acromegaly, respectively, though some excess mortality may persist even in "cured" patients.
authors.affiliation: Department of Endocrinology, The Medical School, College of Medical and Dental Sciences Edgbaston, University of Birmingham, United Kingdom. p.m.stewart@bham.ac.uk
authors.forename: Paul M
authors.initials: PM
authors.lastname: Stewart
authors.forename: Mark
authors.initials: M
authors.lastname: Sherlock
mesh_terms: D002423:Cause of Death; D015897:Comorbidity; D006801:Humans; D009026:Mortality / Q000639:trends; D047748:Pituitary ACTH Hypersecretion / Q000150:complications / Q000453:epidemiology / Q000401:mortality; D010900:Pituitary Diseases / Q000150:complications / Q000453:epidemiology / Q000401:mortality*; D014652:Vascular Diseases / Q000150:complications / Q000453:epidemiology / Q000401:mortality