title: Clinical approach to leukoencephalopathies.
abstract: Recent advances in biochemical and molecular genetics have led to the discovery of new leukoencephalopathies. Despite these advances, many patients with leukoencephalopathy remain undiagnosed. A systematic approach to the investigation of these patients is needed to select the most appropriate testing strategy. In this article, the author presents a clinical and magnetic resonance imaging (MRI) based approach to the evaluation of patients with leukoencephalopathy.
authors.affiliation: Division of Child and Adolescent Neurology, Department of Neurology, Mayo Clinic, 200 First St. SW, Rochester, MN 55901, USA. renaud.deborah@mayo.edu
authors.forename: Deborah L
authors.initials: DL
authors.lastname: Renaud
mesh_terms: D001921:Brain / Q000473:pathology; D006801:Humans; D056784:Leukoencephalopathies / Q000175:diagnosis* / Q000378:metabolism; D008279:Magnetic Resonance Imaging; D009186:Myelin Sheath / Q000473:pathology; D010808:Physical Examination