title: A multicomponent formal [1+2+1+2]-cycloaddition for the synthesis of dihydropyridines.
abstract: Reaction of methoxyvinylmethylketone with different amines and aldehydes under Lewis-acid catalysed conditions results in a novel, formal, step-wise [1+2+1+2]-cycloaddition to give dihydropyridine products.
authors.affiliation: Centre for Sustainable Chemical Processes, Department of Chemistry, Durham University, South Road, Durham, DH1 3LE, UK.
authors.forename: P Ricardo
authors.initials: PR
authors.lastname: Girling
authors.forename: Andrei S
authors.initials: AS
authors.lastname: Batsanov
authors.forename: Hong C
authors.initials: HC
authors.lastname: Shen
authors.forename: Andrew
authors.initials: A
authors.lastname: Whiting
mesh_terms: D000447:Aldehydes / Q000737:chemistry; D000588:Amines / Q000737:chemistry; D002384:Catalysis; D018360:Crystallography, X-Ray; D003500:Cyclization; D004095:Dihydropyridines / Q000138:chemical synthesis* / Q000737:chemistry; D058116:Lewis Acids / Q000737:chemistry; D008968:Molecular Conformation
chemical_list: D000447:Aldehydes; D000588:Amines; D004095:Dihydropyridines; D058116:Lewis Acids