title: A bioelectronic sensor based on canine olfactory nanovesicle-carbon nanotube hybrid structures for the fast assessment of food quality.
abstract: We developed an olfactory-nanovesicle-fused carbon-nanotube-transistor biosensor (OCB) that mimics the responses of a canine nose for the sensitive and selective detection of hexanal, an indicator of the oxidation of food. OCBs allowed us to detect hexanal down to 1 fM concentration in real-time. Significantly, we demonstrated the detection of hexanal with an excellent selectivity capable of discriminating hexanal from analogous compounds such as pentanal, heptanal, and octanal. Furthermore, we successfully detected hexanal in spoiled milk without any pretreatment processes. Considering these results, our sensor platform should offer a new method for the assessment of food quality and contribute to the development of portable sensing devices.
authors.affiliation: Department of Physics and Astronomy, Seoul National University, Seoul, 151-742, Korea.
authors.forename: Juhun
authors.initials: J
authors.lastname: Park
authors.forename: Jong Hyun
authors.initials: JH
authors.lastname: Lim
authors.forename: Hye Jun
authors.initials: HJ
authors.lastname: Jin
authors.forename: Seon
authors.initials: S
authors.lastname: Namgung
authors.forename: Sang Hun
authors.initials: SH
authors.lastname: Lee
authors.forename: Tai Hyun
authors.initials: TH
authors.lastname: Park
authors.forename: Seunghun
authors.initials: S
authors.lastname: Hong
mesh_terms: D000447:Aldehydes / Q000737:chemistry; D000818:Animals; D032701:Biomimetics / Q000295:instrumentation / Q000379:methods*; D015374:Biosensing Techniques / Q000295:instrumentation / Q000379:methods*; D004285:Dogs; D005504:Food Analysis / Q000295:instrumentation / Q000379:methods*; D005506:Food Contamination / Q000032:analysis; D057809:HEK293 Cells; D006801:Humans; D008892:Milk / Q000737:chemistry; D036103:Nanotechnology / Q000295:instrumentation / Q000379:methods*; D037742:Nanotubes, Carbon / Q000737:chemistry*; D009666:Nose; D013997:Time Factors; D014173:Transistors, Electronic
chemical_list: D000447:Aldehydes; D037742:Nanotubes, Carbon; C010463:n-hexanal