title: Tandem oxidative dearomatization/intramolecular Diels-Alder reaction for construction of the tricyclic core of palhinine A.
abstract: A concise construction of the 6/6/5 tricyclic core of Lycopodium alkaloid palhinine A (1) has been accomplished. The developed synthetic strategy featured a tandem oxidative dearomatization/intramolecular Diels-Alder reaction to construct C/D rings and an intramolecular 5-exo-trig radical cyclization to install the B ring of palhinine A (1). The developed approach paves the way for the total synthesis of palhinine A (1).
authors.affiliation: State Key Laboratory of Applied Organic Chemistry, Department of Chemistry, Lanzhou University, Lanzhou 730000, People's Republic of China.
authors.forename: Changgui
authors.initials: C
authors.lastname: Zhao
authors.forename: Huaiji
authors.initials: H
authors.lastname: Zheng
authors.forename: Peng
authors.initials: P
authors.lastname: Jing
authors.forename: Bowen
authors.initials: B
authors.lastname: Fang
authors.forename: Xingang
authors.initials: X
authors.lastname: Xie
authors.forename: Xuegong
authors.initials: X
authors.lastname: She
mesh_terms: D000470:Alkaloids / Q000138:chemical synthesis* / Q000737:chemistry; D003500:Cyclization; D032502:Lycopodium / Q000737:chemistry; D015394:Molecular Structure; D010084:Oxidation-Reduction
chemical_list: D000470:Alkaloids; C553649:palhinine A