title: Evaluation of certain food additives and contaminants.
abstract: This report represents the conclusions of a Joint FAO/WHO Expert Committee convened to evaluate the safety of various food additives, with a view to recommending acceptable daily intakes (ADIs) and to preparing specifications for identity and purity. The Committee also evaluated the risk posed by two food contaminants, with the aim of deriving tolerable intakes where appropriate and advising on risk management options for the purpose of public health protection. The first part of the report contains a general discussion of the principles governing the toxicological evaluation of and assessment of dietary exposure to food additives and contaminants. A summary follows of the Committee's evaluations of technical, toxicological and dietary exposure data for certain food additives (aluminium-containing food additives, Benzoe Tonkinensis, glycerol ester of gum rosin, glycerol ester of tall oil rosin, glycerol ester of wood rosin, octenyl succinic acid modified gum arabic, polydimethyl siloxane, Ponceau 4R, pullulan, pullulanase from Bacillus deromificans expressed in Bacillus licheniformis, Quinoline Yellow and Sunset Yellow FCF) and two food contaminants (cyanogenic glycosides and fumonisins). Specifications for the following food additives were revised: aluminium lakes of colouring matters; beta-apo-8'-carotenal; beta-apo-8'-carotenoic acid ethyl ester; beta-carotene, synthetic; hydroxypropyl methyl cellulose; magnesium silicate, synthetic; modified starches; nitrous oxide; sodium carboxymethyl cellulose; and sucrose monoesters of lauric, palmitic or stearic acid. Annexed to the report are tables summarizing the Committee's recommendations for dietary exposures to and toxicological evaluations of the food additives and contaminants considered.
mesh_terms: D000535:Aluminum / Q000032:analysis / Q000633:toxicity; D001391:Azo Compounds / Q000032:analysis / Q000592:standards / Q000633:toxicity; D002338:Carotenoids / Q000032:analysis / Q000592:standards; D003257:Consumer Product Safety; D004032:Diet / Q000592:standards / Q000706:statistics & numerical data; D004781:Environmental Exposure / Q000032:analysis / Q000592:standards* / Q000706:statistics & numerical data; D005503:Food Additives / Q000032:analysis / Q000633:toxicity*; D005506:Food Contamination / Q000032:analysis* / Q000706:statistics & numerical data; D005995:Glyceryl Ethers / Q000032:analysis / Q000633:toxicity; D017408:Guidelines as Topic; D006801:Humans; D018673:Nutrition Policy; D011634:Public Health; D011804:Quinolines / Q000032:analysis / Q000592:standards / Q000633:toxicity; D018570:Risk Assessment; D012308:Risk Management; D012449:Safety; D014944:World Health Organization; D019207:beta Carotene / Q000032:analysis / Q000592:standards
chemical_list: D001391:Azo Compounds; D005503:Food Additives; D005995:Glyceryl Ethers; D011804:Quinolines; C436746:apo-8'-carotenoic acid; C110652:beta-apo-8'-carotenal; D019207:beta Carotene; C019303:quinoline yellow; D002338:Carotenoids; D000535:Aluminum; C005842:6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt