title: Review of endophthalmitis following Boston keratoprosthesis type 1.
abstract: Endophthalmitis remains one of the most damaging and challenging complications following Boston keratoprosthesis type 1 (KPro) surgery. The authors reviewed the literature from 2001 onward to identify cases of endophthalmitis following KPro surgery and present an additional case of endophthalmitis in a patient with Stevens Johnson syndrome. The prevalence of endophthalmitis between 2001 and 2011 was 5.4%. Gram-positive bacteria are the most common agents responsible for endophthalmitis in this patient population while gram-negative bacteria and fungi are emerging pathogens. Risk factors for endophthalmitis include preoperative diagnosis of cicatricial disease and postoperative infectious keratitis, glaucoma drainage device erosion and non-compliance with antibiotic prophylaxis. Additional studies on the prevention and treatment of endophthalmitis are required to improve the overall prognosis of these patients.
authors.affiliation: Department of Ophthalmology, Centre Hospitalier de l'Université de Montréal, Hôpital Notre-Dame, Montréal, Québec, Canada .
authors.forename: Marie-Claude
authors.initials: MC
authors.lastname: Robert
authors.forename: Krystel
authors.initials: K
authors.lastname: Moussally
authors.forename: Mona
authors.initials: M
authors.lastname: Harissi-Dagher
mesh_terms: D001187:Artificial Organs; D003315:Cornea; D009877:Endophthalmitis / Q000453:epidemiology / Q000382:microbiology*; D015818:Eye Infections, Bacterial / Q000453:epidemiology / Q000382:microbiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009181:Mycoses / Q000453:epidemiology / Q000382:microbiology*; D011183:Postoperative Complications; D019736:Prostheses and Implants; D012307:Risk Factors; D013262:Stevens-Johnson Syndrome / Q000150:complications