title: Hijacking T cell differentiation: new insights in TLX function in T-ALL.
abstract: TLX1 and TLX3 are two closely-related homeobox transcriptional repressors frequently misexpressed and translocated in T cell acute lymphoblastic leukemia (T-ALL). In this issue of Cancer Cell, Dadi et al. provide new insights into how these factors are recruited by ETS-1 to the TCRα enhancer and actively repress differentiation.
authors.affiliation: Howard Hughes Medical Institute and Department of Pathology, NYU School of Medicine, New York, NY 10016, USA.
authors.forename: Bryan
authors.initials: B
authors.lastname: King
authors.forename: Panagiotis
authors.initials: P
authors.lastname: Ntziachristos
authors.forename: Iannis
authors.initials: I
authors.lastname: Aifantis