title: [Study on the secondary metabolites from the marine sponge Phakellia fusca fungi PF18].
abstract: OBJECTIVE
  To study the secondary metabolites from the marine sponge Phakellia fusca epiphytic fungi.
  
  
  METHODS
  The compounds were isolated by column chromatography over silica gel and purified by Sephadex LH-20 column chromatography and preparative TLC. The structures were elucidated by means of physiochemical properties and spectroscopic analyses.
  
  
  RESULTS
  Four compounds were separated and identified as: cyclo-(L-Val-L-Pro) (1), cyclo-(L-Phe-L-Pro) (2), cyclo-(L-Tyr-L-Pro) (3), cyclo-(3-hydroxy-4-methyldecanoyl-Gly-L-Val-D-Leu-L-Ala-L-Phe) (4).
  
  
  CONCLUSIONS
  Compounds 1-4 are obtained from the marine sponge Phakellia fusca epiphytic fungi for the first time.
authors.affiliation: Department of Chemistry, Jinan University, Guangzhou 510632,China. tld-212@163.com
authors.forename: Li-Dan
authors.initials: LD
authors.lastname: Tang
authors.forename: Yuan-Wei
authors.initials: YW
authors.lastname: Liang
authors.forename: Xiao-Jian
authors.initials: XJ
authors.lastname: Liao
authors.forename: Qiu
authors.initials: Q
authors.lastname: Liang
authors.forename: Shi-Hai
authors.initials: SH
authors.lastname: Xu
authors.forename: Zhi-Yong
authors.initials: ZY
authors.lastname: Li
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000737:chemistry / Q000302:isolation & purification*; D047630:Depsipeptides / Q000737:chemistry / Q000302:isolation & purification; D004151:Dipeptides / Q000737:chemistry / Q000302:isolation & purification; D005658:Fungi / Q000737:chemistry* / Q000302:isolation & purification; D008386:Marine Biology; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010456:Peptides, Cyclic / Q000737:chemistry / Q000302:isolation & purification*; D011161:Porifera / Q000382:microbiology*
chemical_list: D000970:Antineoplastic Agents; D047630:Depsipeptides; D004151:Dipeptides; D010456:Peptides, Cyclic; C118540:cyclo(phenylalanyl-prolyl); C531265:scopularide A