title: Enantioselective direct aminalization with primary carboxamides catalyzed by chiral ammonium 1,1'-binaphthyl-2,2'-disulfonates.
abstract: A highly effective catalytic enantioselective direct aminal synthesis was developed. Chiral ammonium 1,1'-binaphthyl-2,2'-disulfonates, which were prepared in situ from (R)-BINSA and achiral amines, promoted the enantioselective addition of primary amides to aromatic aldimines.
authors.affiliation: Graduate School of Engineering, Nagoya University, Furo-cho, Chikusa, Japan.
authors.forename: Manabu
authors.initials: M
authors.lastname: Hatano
authors.forename: Takuya
authors.initials: T
authors.lastname: Ozaki
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Sugiura
authors.forename: Kazuaki
authors.initials: K
authors.lastname: Ishihara
mesh_terms: D000577:Amides / Q000138:chemical synthesis / Q000737:chemistry*; D000586:Amination; D000588:Amines / Q000138:chemical synthesis / Q000737:chemistry*; D006841:Hydrocarbons, Aromatic / Q000138:chemical synthesis / Q000737:chemistry; D007097:Imines / Q000138:chemical synthesis / Q000737:chemistry*; D009281:Naphthalenes / Q000138:chemical synthesis / Q000737:chemistry*; D057786:Peptidomimetics / Q000138:chemical synthesis / Q000737:chemistry; D000644:Quaternary Ammonium Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D013237:Stereoisomerism; D013451:Sulfonic Acids / Q000138:chemical synthesis / Q000737:chemistry*
chemical_list: D000577:Amides; D000588:Amines; D006841:Hydrocarbons, Aromatic; D007097:Imines; D009281:Naphthalenes; D057786:Peptidomimetics; D000644:Quaternary Ammonium Compounds; D013451:Sulfonic Acids; C412330:1,1'-binaphthyl