title: Cardiovascular risk factors in subjects with psoriasis: a cross-sectional general population study.
abstract: BACKGROUND
  Epidemiological data have established an association between cardiovascular disease and psoriasis. Only one general population study has so far compared prevalences of cardiovascular risk factors among subjects with psoriasis and control subjects. We aimed to determine the prevalence of cardiovascular risk factors in subjects with and without psoriasis in the general population.
  
  
  METHODS
  During 2006-2008, a cross-sectional study was performed in the general population in Copenhagen, Denmark. A total of 3471 subjects participated in a general health examination that included assessment of current smoking status, weight, height, waist and hip circumferences, systolic and diastolic blood pressures, resting heart rate, and plasma lipids, hemoglobin A1c, fasting glucose, and insulin levels.
  
  
  RESULTS
  Physician-diagnosed psoriasis was reported by 238 (7.1%) of 3374 participants. There were no differences between subjects with and without psoriasis with regard to traditional cardiovascular risk factors.
  
  
  CONCLUSIONS
  Our results contrast with the hitherto-reported increased prevalence of metabolic syndrome in subjects with psoriasis in the general U.S. population. However, our results agree with those of other previous studies in which the association between mild psoriasis and cardiovascular risk factors is often non-significant. Further controlled research is needed to describe the prevalence of cardiovascular risk factors in subjects with mainly mild to moderate psoriasis in the general population.
authors.affiliation: Department of Dermato-Allergology Cardiology, Copenhagen University Hospital Gentofte, Hellerup, Denmark. peterj01@geh.regionh.dk
authors.forename: Peter
authors.initials: P
authors.lastname: Jensen
authors.forename: Jacob P
authors.initials: JP
authors.lastname: Thyssen
authors.forename: Claus
authors.initials: C
authors.lastname: Zachariae
authors.forename: Peter R
authors.initials: PR
authors.lastname: Hansen
authors.forename: Allan
authors.initials: A
authors.lastname: Linneberg
authors.forename: Lone
authors.initials: L
authors.lastname: Skov
mesh_terms: D000328:Adult; D002318:Cardiovascular Diseases / Q000453:epidemiology*; D003430:Cross-Sectional Studies; D003718:Denmark / Q000453:epidemiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D011565:Psoriasis / Q000453:epidemiology*; D012307:Risk Factors; D012720:Severity of Illness Index; D014505:Urban Population / Q000706:statistics & numerical data