title: Developing a method to identify medicines non-adherence in a community sample of adults with epilepsy.
abstract: The aim is to propose a simple way of identifying patients at risk of antiepileptic drug (AED) non-adherence during epilepsy review (a scheduled consultation to review the patient and their condition). The use of a multi-modal approach to the problem of non-adherence is necessary because of the limitations of existing methods. A mixed methodology was developed in a nested study using a case record review to calculate the medicine possession ratio (MPR) from the AED medication records of a community sample, a literature review and a consensus panel to develop a questionnaire to address how people manage their epilepsy, particularly medicine management, and how to collect information about non-adherence through stated findings in keeping with non-adherent behavior. Results show that a medicine record can be used to estimate the MPR (<80% indicates non-adherence) and that an open and non-confrontational consultation style can be fostered by using key questions within the consultation to identify those at risk of non-adherence.
authors.affiliation: Academic Unit of Primary Medical Care, Medical School, Sheffield, UK. henry.smithson@sheffield.ac.uk
authors.forename: W Henry
authors.initials: WH
authors.lastname: Smithson
authors.forename: Debbie
authors.initials: D
authors.lastname: Hukins
authors.forename: Brigitte
authors.initials: B
authors.lastname: Colwell
authors.forename: Nigel
authors.initials: N
authors.lastname: Mathers
mesh_terms: D000328:Adult; D000927:Anticonvulsants / Q000627:therapeutic use*; D004827:Epilepsy / Q000188:drug therapy / Q000523:psychology*; D005260:Female; D006801:Humans; D008297:Male; D055118:Medication Adherence; D008875:Middle Aged; D012111:Residence Characteristics; D011795:Surveys and Questionnaires; D055815:Young Adult
chemical_list: D000927:Anticonvulsants