title: Copper-catalyzed oxidative trifluoromethylation of terminal alkenes using nucleophilic CF3SiMe3: efficient C(sp3)-CF3 bond formation.
abstract: An efficient C(sp(3))-CF(3) bond-forming reaction via Cu-catalyzed oxidative trifluoromethylation of terminal alkenes has been developed, which proceeds under mild conditions using readily available, less expensive CF(3)SiMe(3) as the source of the CF(3) group. This method allows access to a variety of trifluoromethylated allylic compounds.
authors.affiliation: Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Lu, Shanghai 200032, China.
authors.forename: Lingling
authors.initials: L
authors.lastname: Chu
authors.forename: Feng-Ling
authors.initials: FL
authors.lastname: Qing
mesh_terms: D000475:Alkenes / Q000138:chemical synthesis* / Q000737:chemistry*; D000498:Allyl Compounds / Q000737:chemistry; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D006845:Hydrocarbons, Fluorinated / Q000737:chemistry*; D015394:Molecular Structure; D010084:Oxidation-Reduction; D014297:Trimethylsilyl Compounds / Q000737:chemistry*
chemical_list: C523557:(trifluoromethyl)-trimethylsilane; D000475:Alkenes; D000498:Allyl Compounds; D006845:Hydrocarbons, Fluorinated; D014297:Trimethylsilyl Compounds; D003300:Copper