title: Association of particulate air pollution with daily mortality: the China Air Pollution and Health Effects Study.
abstract: China is one of the few countries with some of the highest particulate matter levels in the world. However, only a small number of particulate matter health studies have been conducted in China. The study objective was to examine the association of particulate matter with an aerodynamic diameter of less than 10 μm (PM(10)) with daily mortality in 16 Chinese cities between 1996 and 2008. Two-stage Bayesian hierarchical models were applied to obtain city-specific and national average estimates. Poisson regression models incorporating natural spline smoothing functions were used to adjust for long-term and seasonal trends of mortality, as well as other time-varying covariates. The averaged daily concentrations of PM(10) in the 16 Chinese cities ranged from 52 μg/m(3) to 156 μg/m(3). The 16-city combined analysis showed significant associations of PM(10) with mortality: A 10-μg/m(3) increase in 2-day moving-average PM(10) was associated with a 0.35% (95% posterior interval (PI): 0.18, 0.52) increase of total mortality, 0.44% (95% PI: 0.23, 0.64) increase of cardiovascular mortality, and 0.56% (95% PI: 0.31, 0.81) increase of respiratory mortality. Females, older people, and residents with low educational attainment appeared to be more vulnerable to PM(10) exposure. Conclusively, this largest epidemiologic study of particulate air pollution in China suggests that short-term exposure to PM(10) is associated with increased mortality risk.
authors.affiliation: School of Public Health, Key Lab of Public Health Safety of the Ministry of Education, Fudan University, Shanghai, China.
authors.forename: Renjie
authors.initials: R
authors.lastname: Chen
authors.forename: Haidong
authors.initials: H
authors.lastname: Kan
authors.forename: Bingheng
authors.initials: B
authors.lastname: Chen
authors.forename: Wei
authors.initials: W
authors.lastname: Huang
authors.forename: Zhipeng
authors.initials: Z
authors.lastname: Bai
authors.forename: Guixiang
authors.initials: G
authors.lastname: Song
authors.forename: Guowei
authors.initials: G
authors.lastname: Pan
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000393:Air Pollutants / Q000032:analysis / Q000633:toxicity*; D000397:Air Pollution / Q000009:adverse effects* / Q000032:analysis; D001499:Bayes Theorem; D002648:Child; D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D004784:Environmental Monitoring; D062665:Epidemiological Monitoring; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D019570:Inhalation Exposure / Q000009:adverse effects* / Q000032:analysis; D008297:Male; D008875:Middle Aged; D015233:Models, Statistical; D009026:Mortality; D052638:Particulate Matter / Q000032:analysis / Q000633:toxicity*; D016012:Poisson Distribution; D012044:Regression Analysis; D012737:Sex Factors; D012959:Socioeconomic Factors; D014504:Urban Health; D055815:Young Adult
chemical_list: D000393:Air Pollutants; D052638:Particulate Matter