title: Functionalization, re-functionalization and rejuvenation of ssDNA nanotemplates.
abstract: Single-stranded DNA (ssDNA) with repetitive sequence was demonstrated to be a versatile nanotemplate for introducing biological activity in a self-assembled manner. Re-functionalization and rejuvenation of the ssDNA nanotemplate were achieved under mild biological conditions without using high temperature and strong alkaline treatment to denature DNA.
authors.affiliation: Institute of Molecular Medicine and Bioengineering, National Chiao Tung University, Hsinchu, Taiwan.
authors.forename: Ming-Yu
authors.initials: MY
authors.lastname: Lin
authors.forename: Fu Han
authors.initials: FH
authors.lastname: Ho
authors.forename: Chung-Yao
authors.initials: CY
authors.lastname: Yang
authors.forename: J Andrew
authors.initials: JA
authors.lastname: Yeh
authors.forename: Yuh-Shyong
authors.initials: YS
authors.lastname: Yang
mesh_terms: D001710:Biotin / Q000737:chemistry / Q000378:metabolism; D004277:DNA, Single-Stranded / Q000737:chemistry*; D006735:Horseradish Peroxidase / Q000378:metabolism; D049329:Nanostructures / Q000737:chemistry*; D036103:Nanotechnology; D009691:Nucleic Acid Denaturation; D012825:Silicon / Q000737:chemistry; D013696:Temperature
chemical_list: D004277:DNA, Single-Stranded; D001710:Biotin; D006735:Horseradish Peroxidase; D012825:Silicon