title: Palladium-catalyzed direct phosphonation of azoles with dialkyl phosphites.
abstract: The first Pd-catalyzed direct phosphonation of azoles with dialkyl phosphites has been achieved without addition of base or acid. This method involves the oxidative cleavage of C-H and P(O)-H bonds and represents an atom-efficiency alternative to the classical phosphonation of Ar-X. A Pd(II)/Pd(IV) mechanism has been studied and proposed.
authors.affiliation: State Key Laboratory for Oxo Synthesis and Selective Oxidation, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, 730000, China.
authors.forename: Chaodong
authors.initials: C
authors.lastname: Hou
authors.forename: Yunlai
authors.initials: Y
authors.lastname: Ren
authors.forename: Rui
authors.initials: R
authors.lastname: Lang
authors.forename: Xiaoxue
authors.initials: X
authors.lastname: Hu
authors.forename: Chungu
authors.initials: C
authors.lastname: Xia
authors.forename: Fuwei
authors.initials: F
authors.lastname: Li
mesh_terms: D001393:Azoles / Q000737:chemistry*; D002384:Catalysis; D010084:Oxidation-Reduction; D010165:Palladium / Q000737:chemistry*; D017905:Phosphites / Q000737:chemistry*
chemical_list: D001393:Azoles; D017905:Phosphites; D010165:Palladium