title: Resistin and cardiovascular disease.
abstract: Resistin has been implicated in coronary atherosclerotic disease and congestive heart failure. Recent studies have extended its involvement in peripheral artery disease. Despite some controversial data, the mainstream clinical literature supports that resistin is associated with both coronary and peripheral artery diseases including ischemic stroke. In this review, the multiple roles of resistin as screening, diagnostic, and prognostic marker for cardiovascular disease are discussed. The independence of resistin in disease prediction and diagnosis appears complicated by its confounders, such as C-reactive protein. A clear-cut biomarker function of resistin in cardiovascular disease needs be clarified by additional large-scale, well-designed prospective studies.
authors.affiliation: Division of Vascular and Endovascular Surgery, Department of Surgery, Stanford University, Stanford, CA 94350, USA.
authors.forename: Qinxue
authors.initials: Q
authors.lastname: Ding
authors.forename: Sharla Powell
authors.initials: SP
authors.lastname: White
authors.forename: Christina
authors.initials: C
authors.lastname: Ling
authors.forename: Wei
authors.initials: W
authors.lastname: Zhou
mesh_terms: D000818:Animals; D015415:Biomarkers / Q000378:metabolism; D002318:Cardiovascular Diseases / Q000175:diagnosis / Q000378:metabolism* / Q000628:therapy; D006801:Humans; D011237:Predictive Value of Tests; D011379:Prognosis; D052243:Resistin / Q000378:metabolism*
chemical_list: D015415:Biomarkers; D052243:Resistin