title: [Systematic review of clinical randomized controlled trials on manipulation treatment for vertebral artery type of cervical spondylosis].
abstract: OBJECTIVE
  To evaluate the safety and efficacy of the manipulation treatment for vertebral artery type of cervical spondylosis and analyze the current status of clinical study.
  
  
  METHODS
  To retrievie the PubMed, OVID, Cochrane library, CBM-disc database, CNKI database, VIP database, 265 literatures of the manipulation treatment of vertebral artery type of cervical spondylosis were collected, including 251 literatures Chinese and 14 literatures English. Among the literatures, 5 studies of Chinese literatures accorded with inclusion criteria. Cochrane systematic review was used to quality evaluation; and 5 studies were used RevMan 4.2 for Meta analysis of literature.
  
  
  RESULTS
  Five documents included a total of 736 patients. Summary of the literature combined OR for the cure rate was 2.93, 95% CI was [2.10,4.08]. Summary OR for the combined efficiency was 3.99, 95% CI was [2.47,6.44]. Manipulation group's cure rate of vertebral artery type of cervical spondylosis was efficient and clearly superior to the other therapies. Expect of the manipulation, the traction and the drugs, hereinafter referred to as "other therapies" (P < 0.01).
  
  
  CONCLUSIONS
  At present, documents included in this study have shown that manipulation treatment on vertebral artery type of cervical spondylosis is safe, both cure rate and the effective rate are much better than other therapies; but the incorporation of a limited number of documents and the quality is not very high, the conclusion is still uncertain, high-quality evidence should be needed to be further validated.
authors.affiliation: Medical Center of Orthopaedics, Shuguang Hospital Affiliated to Shanghai University of TCM, Shanghai 200021, China.
authors.forename: Kai
authors.initials: K
authors.lastname: Guo
authors.forename: Lin
authors.initials: L
authors.lastname: Li
authors.forename: Hong-Sheng
authors.initials: HS
authors.lastname: Zhan
authors.forename: Hui-Hao
authors.initials: HH
authors.lastname: Wang
authors.forename: Yin-Yu
authors.initials: YY
authors.lastname: Shi
mesh_terms: D006801:Humans; D020393:Manipulation, Spinal / Q000379:methods*; D016032:Randomized Controlled Trials as Topic; D055009:Spondylosis / Q000628:therapy*; D014711:Vertebral Artery