title: Informational odds ratio: a useful measure of epidemiologic association in environment exposure studies.
abstract: The informational odds ratio (IOR) measures the post-exposure odds divided by the pre-exposure odds (ie, information gained after knowing exposure status). A desirable property of an adjusted ratio estimate is collapsibility (ie, the combined crude ratio will not change after adjusting for a variable that is not a confounder). Adjusted traditional odds ratios (TORs) are not collapsible. In contrast, Mantel-Haenszel adjusted IORs generally are collapsible. IORs are a useful measure of disease association in environmental case-referent studies, especially when the disease is common in the exposed and/or unexposed groups.
authors.affiliation: Department of Public Health, Brody School of Medicine, Greenville, NC.
authors.forename: Jimmy T
authors.initials: JT
authors.lastname: Efird
authors.forename: Suzanne
authors.initials: S
authors.lastname: Lea
authors.forename: Amanda
authors.initials: A
authors.lastname: Toland
authors.forename: Christopher J
authors.initials: CJ
authors.lastname: Phillips