title: Hijacking leucyl-tRNA synthetase for amino acid-dependent regulation of TORC1.
abstract: TORC1 activity in all eukaryotes is dependent on amino acid availability. However, the mechanism through which TORC1 senses amino acids is still a mystery. In the current issues of Molecular Cell and Cell, Bonfils et al. (2012) and Han et al. (2012) implicate leucyl-tRNA synthetase in this evolving story.
authors.affiliation: Department of Biochemistry and Molecular Genetics, College of Medicine, University of Illinois at Chicago, Chicago, IL 60607, USA. nava@uic.edu
authors.forename: Nava
authors.initials: N
authors.lastname: Segev
authors.forename: Nissim
authors.initials: N
authors.lastname: Hay