title: Intraocular and orbital metastasis as a rare form of clinical presentation of insular thyroid cancer.
abstract: Insular carcinoma of thyroid is a rare tumor, which accounts for 4 to 6% of thyroid malignancies. Clinically and morphologically it is considered to be in an intermediate position between well-differentiated carcinoma of the thyroid (papillary or follicular) and undifferentiated or anaplastic carcinoma of the thyroid. Capsular and blood vessel invasion is seen frequently, and metastases to regional lymph nodes, lungs and bones are common. The initial presentation of distant metastasis in patients with thyroid cancer is rare. Thus metastatic thyroid carcinoma rarely involves the orbit. We report a rare case of choroidal metastasis from insular thyroid carcinoma.
authors.affiliation: Department of nuclear medicine, Okmeydani Training and Research Hospital, 34400 Kagithane, Istanbul, Turkey.
authors.forename: Tevfik
authors.initials: T
authors.lastname: Ozpacaci
authors.forename: Mehmet
authors.initials: M
authors.lastname: Mulazimoglu
authors.forename: Muge Oner
authors.initials: MO
authors.lastname: Tamam
authors.forename: Cem
authors.initials: C
authors.lastname: Leblebici
authors.forename: Kerim
authors.initials: K
authors.lastname: Yildiz
authors.forename: Ercan
authors.initials: E
authors.lastname: Uyanik
authors.forename: Kadir
authors.initials: K
authors.lastname: Eltutar
mesh_terms: D000368:Aged; D002277:Carcinoma / Q000175:diagnosis / Q000532:radiotherapy / Q000556:secondary* / Q000601:surgery; D002830:Choroid Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000556:secondary* / Q000601:surgery; D015353:Eye Enucleation; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007457:Iodine Radioisotopes / Q000627:therapeutic use; D008175:Lung Neoplasms / Q000532:radiotherapy / Q000556:secondary; D037981:Neck Dissection; D009361:Neoplasm Invasiveness; D009918:Orbital Neoplasms / Q000175:diagnosis / Q000556:secondary* / Q000601:surgery; D011379:Prognosis; D019572:Retinal Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000556:secondary* / Q000601:surgery; D013964:Thyroid Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery; D013965:Thyroidectomy
chemical_list: D007457:Iodine Radioisotopes