title: Prognostic significance of the number of lymph nodes in elective neck dissection for tongue and mouth floor cancers.
abstract: The presence of metastatic lymph nodes is a relevant aspect in the treatment of head and neck cancer, bringing about a 50% reduction in survival.
  
  
  OBJECTIVE
  To assess the number of lymph nodes removed in the neck dissection and their relationship with the prognosis.
  
  
  METHODS
  A retrospective study involving 143 patients with tongue and mouth floor epidermoid carcinoma, which histological exam showed no lymph node metastases. Among those, 119 were males and 24 females, with mean age of 54 years. As to the primary tumor site, 65 were in the tongue and 78 in the mouth floor. T stage distribution was of four T1, 84 T2, 36 T3 and 19 T4. We carried out 176 neck dissections, unilateral in 110 cases and bilateral in 33. Of these, 78 were radical and 98 selective. The patients were broken down into three groups, according to the 33 and 66 percentiles of the number of lymph nodes resected.
  
  
  RESULTS
  The mean number of resected lymph nodes was 27; 24 in selective dissections and 31 in the complete ones. We did not have statistically significant differences when associated to the T and N stages.
  
  
  CONCLUSIONS
  The larger number of lymph nodes dissected in the neck dissection identifies the group of better prognoses among pN0 cases.
authors.affiliation: Departamentos de Cirurgia de Cabeça e Pescoço e Otorrinolaringologia, Hospital Heliópolis, São Paulo, SP. hosphel.cpg@terra.com.br
authors.forename: Ali
authors.initials: A
authors.lastname: Amar
authors.forename: Helma Maria
authors.initials: HM
authors.lastname: Chedid
authors.forename: Abrão
authors.initials: A
authors.lastname: Rapoport
authors.forename: Claudio Roberto
authors.initials: CR
authors.lastname: Cernea
authors.forename: Rogério Aparecido
authors.initials: RA
authors.lastname: Dedivitis
authors.forename: Otávio Alberto
authors.initials: OA
authors.lastname: Curioni
authors.forename: Lenine Garcia
authors.initials: LG
authors.lastname: Brandão
mesh_terms: D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000556:secondary / Q000601:surgery; D005260:Female; D006801:Humans; D008197:Lymph Node Excision / Q000706:statistics & numerical data*; D008198:Lymph Nodes / Q000601:surgery*; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009060:Mouth Floor; D009367:Neoplasm Staging; D011379:Prognosis; D012189:Retrospective Studies; D014062:Tongue Neoplasms / Q000473:pathology / Q000601:surgery*; D055815:Young Adult