title: Lipoatrophic panniculitis of the ankles in childhood:  differential diagnosis with subcutaneous panniculitis-like T-cell lymphoma.
abstract: We describe the clinical, histopathologic, immunohistochemical, and molecular findings in an additional case of lipoatrophic panniculitis selectively involving the ankles in a 12-year-old boy. This idiopathic, rarely reported entity is presumed to have an autoimmune pathogenesis. Histological findings are a lipophagic lobular panniculits, that in our case featured focally increased numbers of lymphocytes rimming the adipocytes, and infiltration of vascular walls by mildly atypical lymphoid cells, raising the differential diagnosis of subcutaneous panniculitis-like T-cell lymphoma.
authors.affiliation: Servicio de Anatomía Patológica, Capio Fundación Jiménez Díaz, Madrid, Spain. csantonja@fjd.es
authors.forename: Carlos
authors.initials: C
authors.lastname: Santonja
authors.forename: Inés
authors.initials: I
authors.lastname: Gonzalo
authors.forename: Marta
authors.initials: M
authors.lastname: Feito
authors.forename: MaríaJosé
authors.initials: M
authors.lastname: Beato-Merino
authors.forename: Luis
authors.initials: L
authors.lastname: Requena
mesh_terms: D017667:Adipocytes / Q000473:pathology; D000842:Ankle; D001284:Atrophy; D002648:Child; D003240:Connective Tissue Diseases / Q000175:diagnosis*; D003937:Diagnosis, Differential; D006801:Humans; D016399:Lymphoma, T-Cell / Q000175:diagnosis*; D008297:Male; D015434:Panniculitis / Q000175:diagnosis* / Q000188:drug therapy; D012878:Skin Neoplasms / Q000175:diagnosis*; D050151:Subcutaneous Fat / Q000473:pathology*