title: Calming down T cell acute leukemia.
abstract: Signaling from class I phosphoinositide 3-kinase (PI3K) is often deregulated in leukemia and lymphoma, but which isoforms are involved in T cell acute lymphoblastic leukemia (T-ALL) was not known. In this issue of Cancer Cell, Subramaniam et al. show that T-ALL can be tamed by inhibiting γ and δ PI3K isoforms.
authors.affiliation: Molecular Biotechnology Center, University of Torino, Torino, Italy. emilio.hirsch@unito.it
authors.forename: Emilio
authors.initials: E
authors.lastname: Hirsch
authors.forename: Roberto
authors.initials: R
authors.lastname: Chiarle