title: Rhodium-catalyzed oxidative C2-acylation of indoles with aryl and alkyl aldehydes.
abstract: A rhodium-catalyzed oxidative C2-acylation of indoles with aryl and alkyl aldehydes via C-H bond activation is described. The reaction is highly atom-economic and provides easy access to a wide variety of 2-aroylindoles.
authors.affiliation: Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Road Zu Chong Zhi, Zhangjiang Hi-Tech Park, Shanghai 201203, PR China.
authors.forename: Bing
authors.initials: B
authors.lastname: Zhou
authors.forename: Yaxi
authors.initials: Y
authors.lastname: Yang
authors.forename: Yuanchao
authors.initials: Y
authors.lastname: Li
mesh_terms: D000215:Acylation; D000447:Aldehydes / Q000737:chemistry*; D000475:Alkenes / Q000737:chemistry; D000480:Alkynes / Q000737:chemistry; D002244:Carbon / Q000737:chemistry; D002384:Catalysis; D007211:Indoles / Q000737:chemistry*; D010084:Oxidation-Reduction; D012238:Rhodium / Q000737:chemistry*
chemical_list: D000447:Aldehydes; D000475:Alkenes; D000480:Alkynes; D007211:Indoles; D002244:Carbon; D012238:Rhodium