title: Dogs of nomadic pastoralists in northern Kenya are reservoirs of plasmid-mediated cephalosporin- and quinolone-resistant Escherichia coli, including pandemic clone B2-O25-ST131.
abstract: Resistance in Escherichia coli isolates colonizing gastrointestinal tracts of dogs, cats, and their owners in Northern Kenya was investigated with an emphasis on extended-spectrum beta-lactamases (ESBLs). Totals of 47 (22%, n = 216), 2 (4%, n = 50), and 4 (17%, n = 23) CTX-M-15-producing E. coli isolates were obtained from dogs, cats, and humans, respectively. CTX-M-15-producing E. coli isolates with identical PFGE profiles were detected in animals and humans living in the same area.
authors.affiliation: Department of Biology and Wildlife Diseases, Faculty of Veterinary Hygiene and Ecology, University of Veterinary and Pharmaceutical Sciences Brno, Brno, Czech Republic. albkat@seznam.cz
authors.forename: Katerina
authors.initials: K
authors.lastname: Albrechtova
authors.forename: Monika
authors.initials: M
authors.lastname: Dolejska
authors.forename: Alois
authors.initials: A
authors.lastname: Cizek
authors.forename: Dagmar
authors.initials: D
authors.lastname: Tausova
authors.forename: Jiri
authors.initials: J
authors.lastname: Klimes
authors.forename: Lily
authors.initials: L
authors.lastname: Bebora
authors.forename: Ivan
authors.initials: I
authors.lastname: Literak
mesh_terms: D000818:Animals; D002415:Cats; D002511:Cephalosporins / Q000494:pharmacology*; D004285:Dogs; D024901:Drug Resistance, Multiple, Bacterial / Q000235:genetics; D004926:Escherichia coli / Q000187:drug effects* / Q000235:genetics*; D006801:Humans; D007630:Kenya; D010957:Plasmids / Q000235:genetics*; D015363:Quinolones / Q000494:pharmacology*; D001618:beta-Lactamases / Q000235:genetics* / Q000378:metabolism
chemical_list: D002511:Cephalosporins; D015363:Quinolones; D001618:beta-Lactamases