title: A new asymmetric diamide from the seed cake of Jatropha curcas L.
abstract: A new asymmetric diamide (E)-N-(3-acetamidopropyl)-cinnamamide named curcamide (1) has been isolated from the ethanol extract of the seed cake of Jatropha curcas L. along with 7 known compounds identified as isoamericanin (2), isoprincepin (3), caffeoylaldehyde (4), isoferulaldehyde (5), glycerol monooleate (6), syringaldehyde (7), and β-ethyl-d-glucopyranoside (8). The synthesis and antibacterial activity of the new compound have been also studied.
authors.affiliation: Key Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education, College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou 571158, PR China.
authors.forename: Licheng
authors.initials: L
authors.lastname: Yao
authors.forename: Changri
authors.initials: C
authors.lastname: Han
authors.forename: Guangying
authors.initials: G
authors.lastname: Chen
authors.forename: Xiaoping
authors.initials: X
authors.lastname: Song
authors.forename: Yonghui
authors.initials: Y
authors.lastname: Chang
authors.forename: Wenxia
authors.initials: W
authors.lastname: Zang
mesh_terms: D000577:Amides / Q000737:chemistry*; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology; D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D045744:Cell Line, Tumor; D002934:Cinnamates / Q000737:chemistry*; D003958:Diamide / Q000737:chemistry*; D006801:Humans; D031286:Jatropha / Q000737:chemistry*; D008826:Microbial Sensitivity Tests; D012639:Seeds
chemical_list: D000577:Amides; D000900:Anti-Bacterial Agents; D000972:Antineoplastic Agents, Phytogenic; D002934:Cinnamates; C581075:curcamide; D003958:Diamide