title: Efficacy of omeprazole paste in the prevention of gastric ulcers in 2 years old Thoroughbreds.
abstract: Prevalence of equine gastric ulcer syndrome in 85 young Thoroughbreds was investigated. The presence of gastric ulcers was confirmed in 27.1% (23/85) of the horses by endoscopic examination. Sixty-two horses without gastric ulcers were allocated randomly to either the treated group (31 horses) or sham-dosed control group (31 horses) in order to investigate the efficacy of omeprazole oral paste in the prevention of gastric ulcers. At the second endoscopic examination conducted after 28 days of administration, only 1 horse in the treated group developed gastric ulcers, while 12 horses developed gastric ulcers in the control group. Based on these data, the efficacy of omeprazole in prevention of equine gastric ulcers in young Thoroughbreds during the training period was confirmed.
authors.affiliation: Hidaka Training and Research Center, Japan Racing Association, 535-13 Nishicha, Urakawa-gun, Hokkaido 057-0171, Japan. Yoshiro_Endo@jra.go.jp
authors.forename: Yoshiro
authors.initials: Y
authors.lastname: Endo
authors.forename: Takeru
authors.initials: T
authors.lastname: Tsuchiya
authors.forename: Fumio
authors.initials: F
authors.lastname: Sato
authors.forename: Harutaka
authors.initials: H
authors.lastname: Murase
authors.forename: Takaya
authors.initials: T
authors.lastname: Omura
authors.forename: Kenji
authors.initials: K
authors.lastname: Korosue
authors.forename: Yasuo
authors.initials: Y
authors.lastname: Nambo
authors.forename: Mutsuki
authors.initials: M
authors.lastname: Ishimaru
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Wakui
mesh_terms: D000284:Administration, Oral; D000818:Animals; D000897:Anti-Ulcer Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D006734:Horse Diseases / Q000188:drug therapy*; D006736:Horses; D009853:Omeprazole / Q000008:administration & dosage / Q000627:therapeutic use*; D013276:Stomach Ulcer / Q000517:prevention & control / Q000662:veterinary*
chemical_list: D000897:Anti-Ulcer Agents; D009853:Omeprazole