title: Preliminary experience with 18f-fluoro-deoxy-glucose positron emission tomography/computed tomography in pediatric oncology patients.
abstract: The aim of this study was to present preliminary experience with FDG PET/CT in pediatric oncology patients in National PET Center, Clinical Center of Serbia and to asses its impact on management of malignancies in children. 33 FDG PET/CT scans were performed on 30 pediatric patients. PET/CT imaging was performed for staging the disease, assessing therapy efficacy and diagnosing recurrent or metastatic disease. FDG PET/CT changed the stage of the disease in 60.6% (20/33) of the cases. 14 patients were down-staged after PET/CT, mostly patients with Hodgkin's disease, were in 7/10 cases PET/CT showed no activity in residual masses. Six scans led to upstage of the disease. In three cases PET/CT did not change the stage of disease, but has showed new distant metastases. In conclusion, FDG PET/CT showed important role in managing pediatric patients with different malignancies and was useful complementary diagnostic tool to conventional imaging methods.
authors.affiliation: Faculty of Medicine University of Belgrade Center for Nuclear medicine, Clinical Center of Serbia.
authors.forename: Strahinja
authors.initials: S
authors.lastname: Odalović
authors.forename: Dragana
authors.initials: D
authors.lastname: Sobić-Saranović
authors.forename: Smiljana
authors.initials: S
authors.lastname: Pavlović
authors.forename: Isidora
authors.initials: I
authors.lastname: Grozdić
authors.forename: Djordjije
authors.initials: D
authors.lastname: Saranović
authors.forename: Milorad
authors.initials: M
authors.lastname: Petrović
authors.forename: Aleksandar
authors.initials: A
authors.lastname: Milovanović
authors.forename: Zorica
authors.initials: Z
authors.lastname: Petrasinović
authors.forename: Aleksandra
authors.initials: A
authors.lastname: Djurić-Stefanović
authors.forename: Vladimir
authors.initials: V
authors.lastname: Obradović
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008297:Male; D064847:Multimodal Imaging; D009369:Neoplasms / Q000000981:diagnostic imaging*; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals; D014057:Tomography, X-Ray Computed; D055815:Young Adult
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18