title: Recurrence from primary and secondary glomerulopathy after renal transplant.
abstract: Glomerulonephritis is the primary cause of end-stage renal failure in 30-50% of kidney transplant recipients and recurrence of the initial disease is an important determinant of long-term graft outcome after transplantation. Although renal transplantation remains the best treatment option for patients with end stage renal diseases in most cases, diagnosis and management of recurrences of glomerulopathies are critical for the optimization and improvement of long-term kidney transplant graft survival and provide a unique opportunity to explore the pathogenesis of native kidney disease. This review aims to update knowledge for a large panel of recurrent primary and secondary glomerulonephritis after kidney transplantation, excluding diabetic nephropathy including primary focal and segmental glomerulosclerosis, membranous nephropathy, IgA nephropathy, membranoproliferative glomerulonephritis, lupus, vasculitis but also less usual secondary nephropathy related to sarcoidosis, AA and AL amyloidosis, monoclonal immunoglobulin deposition disease, and fibrillary glomerulonephritis.
authors.affiliation: Université Paris Descartes, Sorbonne Paris Cité & Service de Transplantation Rénale Adulte, Hôpital Necker, AP-HP, Paris, France.
authors.forename: Guillaume
authors.initials: G
authors.lastname: Canaud
authors.forename: Vincent
authors.initials: V
authors.lastname: Audard
authors.forename: Tomek
authors.initials: T
authors.lastname: Kofman
authors.forename: Philippe
authors.initials: P
authors.lastname: Lang
authors.forename: Christophe
authors.initials: C
authors.lastname: Legendre
authors.forename: Philippe
authors.initials: P
authors.lastname: Grimbert
mesh_terms: D000328:Adult; D000686:Amyloidosis / Q000150:complications; D019867:Anti-Glomerular Basement Membrane Disease / Q000150:complications; D056648:Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis / Q000150:complications; D016736:Antiphospholipid Syndrome / Q000150:complications; D002648:Child; D005921:Glomerulonephritis / Q000150:complications*; D005922:Glomerulonephritis, IGA / Q000150:complications; D015432:Glomerulonephritis, Membranoproliferative / Q000150:complications; D015433:Glomerulonephritis, Membranous / Q000150:complications; D005923:Glomerulosclerosis, Focal Segmental / Q000503:physiopathology; D006085:Graft Survival; D006801:Humans; D011695:IgA Vasculitis / Q000150:complications; D007674:Kidney Diseases / Q000150:complications; D007676:Kidney Failure, Chronic / Q000209:etiology*; D016030:Kidney Transplantation / Q000009:adverse effects*; D008180:Lupus Erythematosus, Systemic / Q000150:complications; D012008:Recurrence