title: Construction of the biaryl-part of vancomycin aglycon via atropo-diastereoselective Suzuki-Miyaura coupling.
abstract: An atropo-diastereoselective synthesis with dr up to 98/2 towards the biaryl subunit of vancomycin based on the use of enantiopure β-hydroxysulfoxide derivatives as novel chiral auxiliary is reported.
authors.affiliation: CNRS/Université de Strasbourg (ECPM), UMR 7509, 25 Rue Becquerel, F-67087 Strasbourg, France.
authors.forename: Timo
authors.initials: T
authors.lastname: Leermann
authors.forename: Pierre-Emmanuel
authors.initials: PE
authors.lastname: Broutin
authors.forename: Frédéric R
authors.initials: FR
authors.lastname: Leroux
authors.forename: Françoise
authors.initials: F
authors.lastname: Colobert
mesh_terms: D015394:Molecular Structure; D013237:Stereoisomerism; D014640:Vancomycin / Q000031:analogs & derivatives / Q000737:chemistry*
chemical_list: D014640:Vancomycin