title: Early intervention in bipolar disorder: the Jano program at Hospital Universitario Marqués de Valdecilla.
abstract: In order to improve relapse and recurrence prevention in bipolar disorder, the purposes of this paper are: (i) to summarize the evidence published on treatments for this disorder, particularly on psychological interventions in its early phases; (ii) to provide a description of the Jano Intervention and Research Program on the Early Phases of Bipolar Disorder, which is being developed at Valdecilla Hospital (Santander, Spain). Firstly, we review the data from randomized controlled trials and systematic reviews regarding four psychotherapies proven to be effective in the treatment of bipolar disorder: psychoeducation, cognitive-behavioral therapy, family therapy and interpersonal and social rhythm therapy. Secondly, we display a systematic review on the effectiveness of psychological therapies during the early stage of bipolar disorder. Out of 456 studies, all were excluded due to not meeting the inclusion criteria. Finally, we outline the Jano Program, which provides psychiatric management, psychoeducation, psychotherapy and family therapy for patients in the early stage of bipolar disorder. Several standardized clinical, social and neuropsychological tests are administered to the patients at the beginning of the program, and also at 2, 4, 6 and 8 weeks, 3 and 6 months, 1, 2, 3 and 5 years later.
  
  
  CONCLUSIONS
  It's necessary to enlarge the sample and finish our data collection in order to determine the effectiveness and efficiency of this kind of program, and specially of its psychological components. Early intervention for bipolar disorder may need to be adapted in some way from usual treatments to better reach our goals.
authors.affiliation: Hospital Universitario Marqués de Valdecilla, Santander, España. sagonzalez@humv.es
authors.forename: Sara
authors.initials: S
authors.lastname: González
authors.forename: Jesús
authors.initials: J
authors.lastname: Artal
authors.forename: Elsa
authors.initials: E
authors.lastname: Gómez
authors.forename: Patricia
authors.initials: P
authors.lastname: Caballero
authors.forename: Jacqueline
authors.initials: J
authors.lastname: Mayoral
authors.forename: Teresa
authors.initials: T
authors.lastname: Moreno
authors.forename: Mario
authors.initials: M
authors.lastname: Alvarez-Jiménez
authors.forename: Sarah
authors.initials: S
authors.lastname: Gook
authors.forename: María C
authors.initials: MC
authors.lastname: Villacorta
authors.forename: Alfonso
authors.initials: A
authors.lastname: Higuera
authors.forename: José Luis
authors.initials: JL
authors.lastname: Vázquez-Barquero
mesh_terms: D001714:Bipolar Disorder / Q000628:therapy*; D061345:Early Medical Intervention; D019317:Evidence-Based Medicine; D006785:Hospitals, University; D006801:Humans; D016032:Randomized Controlled Trials as Topic; D013030:Spain