title: Frequency and changes in trends of leading risk factors of coronary heart disease in women in the city of Novi Sad during a 20-year period.
abstract: BACKROUND/AIM: From 1984 to 2004 the city of Novi Sad participated through its Health Center "Novi Sad" in the international Multinational MONItoring of Trends and Determinants in CArdiovascular Disease (MONICA) project, as one of the 38 research centers in 21 countries around the world. The aim of this study was to determine frequency and changes of trends in leading risk factors of coronary heart disease (CHD) and to analyze the previous trend of movement of coronary event in women in Novi Sad during a 20-year period.
  
  
  METHODS
  In 2004, the fourth survey within MONICA project was conducted in the city of Novi Sad. The representative sample included 1,041 women between the age of 25 and 74. The prevalence of risk factors in CHD such as smoking, high blood pressure, elevated blood cholesterol, elevated blood glucose and obesity was determined. Also, indicators of risk factors and rates of coronary events in women were compared with the results from MONICA project obtained in previous three screens, as well as with the results from other research centres. chi2-test, linear trend and correlartion coefficient were used in statistical analysis of results obtained.
  
  
  RESULTS
  It was observed that during a 20-year period covered by the study, the prevalence of the leading risk factors for the development of CHD in the surveyed women was significantly increasing and in positive correlation with the values of linear trend. Also, the increase of morbidity rates and mortality rates of coronary event were in positive correlation. The decrease was only recorded in the period from 1985-1989 (the implementation of the intervention programme).
  
  
  CONCLUSIONS
  Upon analysing the increase in prevalence of leading risk factors of CHD and significant increase in the rates of coronary event, we can conclude that health status of women in Novi Sad during a 20-year period was deteriorating.
authors.affiliation: Medical Faculty, University of Novi Sad, Novi Sad, Serbia. amim@eunet.rs
authors.forename: Dusica
authors.initials: D
authors.lastname: Rakić
authors.forename: Djordje
authors.initials: D
authors.lastname: Jakovljević
mesh_terms: D000328:Adult; D000368:Aged; D003327:Coronary Disease / Q000453:epidemiology / Q000209:etiology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D012307:Risk Factors; D055771:Serbia / Q000453:epidemiology