title: Aerobic amide bond formation with N-hydroxysuccinimide.
abstract: Breathe easy: Molecular oxygen is one of the most abundant, atom-efficient, and economical oxidants. An aerobic oxidative amide formation from aldehydes and amines is reported. The method uses a catalytic amount of Co(OAc)(2)  and N-hydroxysuccinimide as reaction promoters. It is applicable to chiral substrates without loss of their optical purity.
authors.affiliation: Department of Chemistry and School for Green Chemistry and Engineering, The University of Toledo, Toledo, OH 43606, USA.
authors.forename: Haoyi
authors.initials: H
authors.lastname: Yao
authors.forename: Kana
authors.initials: K
authors.lastname: Yamamoto
mesh_terms: D000447:Aldehydes / Q000737:chemistry; D000577:Amides / Q000737:chemistry*; D000588:Amines / Q000737:chemistry; D010084:Oxidation-Reduction; D010100:Oxygen / Q000737:chemistry*; D013388:Succinimides / Q000737:chemistry*
chemical_list: D000447:Aldehydes; D000577:Amides; D000588:Amines; D013388:Succinimides; C001426:N-hydroxysuccinimide; D010100:Oxygen