title: Lewis acid-catalyzed, copper(II)-mediated synthesis of heteroaryl thioethers under base-free conditions.
abstract: A Lewis acid (Ag(I), Ni(II), or Fe(II)) catalyzed, Cu(II)-mediated thiolation reaction between heteroarenes and thiols was achieved with good yield under base-free conditions. DMSO could serve as an effective methylthiolation reagent for the synthesis of heterocyclic methyl thioethers.
authors.affiliation: Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China.
authors.forename: Chao
authors.initials: C
authors.lastname: Dai
authors.forename: Zhaoqing
authors.initials: Z
authors.lastname: Xu
authors.forename: Fei
authors.initials: F
authors.lastname: Huang
authors.forename: Zhengkun
authors.initials: Z
authors.lastname: Yu
authors.forename: Yan-Feng
authors.initials: YF
authors.lastname: Gao
mesh_terms: D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D006571:Heterocyclic Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D058116:Lewis Acids / Q000737:chemistry*; D008670:Metals / Q000737:chemistry*; D015394:Molecular Structure; D013440:Sulfides / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D006571:Heterocyclic Compounds; D058116:Lewis Acids; D008670:Metals; D013440:Sulfides; D003300:Copper