title: Treatment of γ-aminobutyric acid B receptor-antibody autoimmune encephalitis with oral corticosteroids.
abstract: BACKGROUND
  Autoimmune encephalitis is increasingly identified as a cause of nonviral, idiopathic encephalitis. Present treatment algorithms recommend costly immune-modulating treatments and do not identify a role for oral corticosteroids.
  
  
  OBJECTIVE
  To present a patient with γ-aminobutyric acid(B) receptor-antibody encephalitis before and after treatment with oral corticosteroids.
  
  
  METHODS
  Case report.
  
  
  METHODS
  The inpatient course as well as outpatient follow-up is discussed.
  
  
  METHODS
  A 43-year-old man with initial presentation of seizures and altered mental status.
  
  
  METHODS
  Our patient was treated with an extended course of oral corticosteroids as an outpatient.
  
  
  RESULTS
  After treatment with oral corticosteroids, our patient had steady clinical improvement, achieved seizure freedom, and experienced improved mental status to within normal limits.
  
  
  CONCLUSIONS
  This case supports the use of low-cost oral corticosteroids in treating patients with γ-aminobutyric acid(B) receptor-antibody encephalitis.
authors.affiliation: Department of Neurology, University of California, Davis Medical Center, Sacramento, 95817, USA. daniel.goldenholz@ucdmc.ucdavis.edu
authors.forename: Daniel M
authors.initials: DM
authors.lastname: Goldenholz
authors.forename: Victoria S S
authors.initials: VS
authors.lastname: Wong
authors.forename: Lisa M
authors.initials: LM
authors.lastname: Bateman
authors.forename: Michelle
authors.initials: M
authors.lastname: Apperson
authors.forename: Bjorn
authors.initials: B
authors.lastname: Oskarsson
authors.forename: Shahrzad
authors.initials: S
authors.lastname: Akhtar
authors.forename: Vicki
authors.initials: V
authors.lastname: Wheelock
mesh_terms: D000284:Administration, Oral; D000305:Adrenal Cortex Hormones / Q000008:administration & dosage*; D000328:Adult; D001927:Brain Diseases / Q000188:drug therapy* / Q000276:immunology*; D004660:Encephalitis; D005500:Follow-Up Studies; D050031:Hashimoto Disease / Q000188:drug therapy* / Q000276:immunology*; D006801:Humans; D008297:Male; D018080:Receptors, GABA-B / Q000276:immunology*; D016896:Treatment Outcome
chemical_list: D000305:Adrenal Cortex Hormones; D018080:Receptors, GABA-B