title: Biological Activities and Corresponding Sar Analysis of Andrographolide and its Derivatives.
abstract: In recent years pharmaceutical chemists have synthesized large numbers of andrographolide derivatives, which bear important biological activities such as anti-inflammatory, antibacterial, antivirus, antitumor, antidiabetic, and antifeedant. Consequently, the corresponding SAR presents more and more pronounced. This paper aimed to review all the available literature on this field, which highlighted the significant achievements on the structural modification and SAR of andrographolide and its derivatives.
authors.affiliation: Center of Drug Discovery, School of Pharmacy, China Pharmaceutical University, Nanjing 210009, China.
authors.forename: Bin
authors.initials: B
authors.lastname: Zhou
authors.forename: Dayong
authors.initials: D
authors.lastname: Zhang
authors.forename: Xiaoming
authors.initials: X
authors.lastname: Wu