title: Novel chiral selector based on mefloquine--a comparative NMR study to elucidate intermolecular interactions with acidic chiral selectands.
abstract: The synthesis, ab initio calculations, and a comparative nuclear magnetic resonance study of a novel chiral mefloquine-based selector (SO) are presented. On a series of variously N-acyl protected leucine selectands (SAs), a feasibility study of mefloquine carbamate as a basic chiral solvating agent, and potential fluorophilic high-performance liquid chromatography selector has been undertaken and evaluated. An analogy is drawn between the new SO and tert-butylcarbamoyl quinidine as a reference.
authors.affiliation: Institute of Analytical Chemistry, University of Vienna, 1090 Vienna, Austria. Michal.Kohout@univie.ac.at
authors.forename: Michal
authors.initials: M
authors.lastname: Kohout
authors.forename: Hanspeter
authors.initials: H
authors.lastname: Kählig
authors.forename: Denise
authors.initials: D
authors.lastname: Wolrab
authors.forename: Alexander
authors.initials: A
authors.lastname: Roller
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Lindner