title: Vasectomy reversal using a microsurgical three-layer technique: one surgeon's experience over 18 years with 1300 patients.
abstract: The technique and the results of microsurgical vasectomy reversal in a single-centre study over 18 years are presented. Both vasovasostomy (VV) and epididymovasostomy (EV) were carried out in a three-layer technique. With strict adherence to the strategy, end-to-end VV was only performed if spermatozoa had been demonstrated at the epididymal stump of the vas. In all other cases, EV was carried out in a preocclusive region of the epididymal tubule. The outpatient procedure of refertilization was associated with a very low complication rate, which underlines its minimal-invasive character. The follow-up rate was 71%, the overall patency rate was 89% and the pregnancy rate was 59%. Secondary azoospermia was only observed in 1% of the patients. In relation to the intervals of obstruction, the patency and pregnancy rates were higher after short-term obstruction than after long-term obstruction. Correspondingly, higher success rates were found after VV than after EV. This is understandable because the probability for indication of EV increases with longer periods of obstruction. There is a significant discrepancy between patency and pregnancy rates that is likely to be caused by a relevant number of patients with post-operative asthenozoospermia. The duration of obstruction is an important factor concerning epididymal damage, but it only disproportionately affects the results of refertilization if the technology of EV is implemented consistently in case of an epididymal granuloma. Good clinical results are achieved with this strategy, as evidenced by pregnancy rates and semen analyses.
authors.affiliation: Andrologie-Centrum-Muenchen, Munich, Germany. j.u.schwarzer@gmx.de
authors.forename: J U
authors.initials: JU
authors.lastname: Schwarzer
mesh_terms: D000328:Adult; D000368:Aged; D053627:Asthenozoospermia; D004822:Epididymis / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D008866:Microsurgery / Q000379:methods*; D008875:Middle Aged; D011247:Pregnancy; D018873:Pregnancy Rate; D055101:Semen Analysis; D014649:Vas Deferens / Q000601:surgery; D014669:Vasovasostomy / Q000379:methods*