title: Analysis of blood-based gene expression signature in first-episode psychosis.
abstract: Blood-based transcriptomic signature in psychosis is an alternative to a brain-based signature. In this study, we profiled whole-blood RNA from 26 patients with first-episode psychosis, and 26 matching controls. We identified a 400-gene signature that classified patients from controls accurately and tested the robustness using other modelling methods.
authors.affiliation: Department of General Psychiatry 1 & Research Division, Institute of Mental Health/Woodbridge Hospital, and Office of Clinical Sciences, Duke-National University of Singapore Graduate Medical School, Singapore. jimmy_lee@imh.com.sg
authors.forename: Jimmy
authors.initials: J
authors.lastname: Lee
authors.forename: Liang-Kee
authors.initials: LK
authors.lastname: Goh
authors.forename: Gengbo
authors.initials: G
authors.lastname: Chen
authors.forename: Swapna
authors.initials: S
authors.lastname: Verma
authors.forename: Chay-Hoon
authors.initials: CH
authors.lastname: Tan
authors.forename: Tih-Shih
authors.initials: TS
authors.lastname: Lee
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D008297:Male; D011618:Psychotic Disorders / Q000235:genetics*; D059467:Transcriptome