title: The clinical spectrum of adrenocortical hyperplasia.
abstract: OBJECTIVE
  To describe the significance of a common adrenal radiological finding on computed tomography or MRI.
  
  
  RESULTS
  Bilateral adrenocortical hyperplasia is the common expression of a variety of adrenal disorders, and its cause needs to be properly assessed in order to institute appropriate management.
  
  
  CONCLUSIONS
  Behind the radiological finding of bilateral adrenal enlargement, there is a spectrum of diseases that require diagnostic evaluation and management. Many cases are benign and not associated with abnormalities of endocrine function. However, these abnormalities may develop years after the initial diagnosis has been made.
authors.affiliation: Division of Metabolism, Endocrinology and Diabetes, Endocrine Oncology Program, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan 48109, USA. dschtein@umich.edu
authors.forename: David E
authors.initials: DE
authors.lastname: Schteingart
mesh_terms: D000312:Adrenal Hyperplasia, Congenital / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy; D003480:Cushing Syndrome / Q000175:diagnosis* / Q000503:physiopathology / Q000601:surgery; D018450:Disease Progression; D005260:Female; D006801:Humans; D006929:Hyperaldosteronism / Q000175:diagnosis* / Q000188:drug therapy / Q000503:physiopathology; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D000451:Mineralocorticoid Receptor Antagonists / Q000627:therapeutic use*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D000451:Mineralocorticoid Receptor Antagonists