title: Antimicrobial photodynamic therapy and photodynamic inactivation, or killing bugs with dyes and light--a symposium-in-print.
abstract: In antimicrobial photodynamic therapy, the photosensitizer (PS) in its ground singlet state absorbs light to give the excited singlet state that can transition to the long-lived triplet state. This PS triplet may undergo energy transfer (Type 2) or electron transfer (Type 1) to oxygen to form reactive oxygen species (singlet oxygen and/or hydroxyl radicals) that can kill both Gram-positive and Gram-negative bacteria and fungi. Infections in animal models can also be treated.
authors.forename: Michael R
authors.initials: MR
authors.lastname: Hamblin
mesh_terms: D000890:Anti-Infective Agents / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects; D004396:Coloring Agents / Q000494:pharmacology*; D005658:Fungi / Q000187:drug effects; D008027:Light; D010778:Photochemotherapy
chemical_list: D000890:Anti-Infective Agents; D004396:Coloring Agents