title: A randomized study of sodium hypochlorite versus formocresol pulpotomy in primary molar teeth.
abstract: BACKGROUND
  Alternatives to vital pulpotomy treatment in primary teeth are being sought because of the high formaldehyde content of traditional formocresol (FC) pulpotomy medicaments.
  
  
  OBJECTIVE
  The aim was to compare the clinical and radiographic success of vital pulpotomy treatment in primary molars using 3% sodium hypochlorite (NaOCl) versus a 1:5 dilution of Buckley's FC.
  
  
  METHODS
  Pulpotomies were performed in primary molars of healthy children between 3 and 10 years old. Sixty-five primary teeth were randomized into two groups that were evaluated for treatment outcomes. Following treatment, the pulp chamber was filled with zinc oxide eugenol (ZnOE) and restored with a stainless steel crown cemented with glass ionomer cement. Clinical and radiographic outcomes were recorded at 6 and 12 months.
  
  
  RESULTS
  The control (FC) and experimental (NaOCl) groups demonstrated 100% clinical success at 6 and 12 months. The NaOCl group had 86% (19/22) radiographic success at 6 months and 80% (12/15) at 12 months. The FC group had 84% (21/25) radiographic success at 6 months and 90% (9/10) at 12 months. No significant differences were found in the radiographic outcomes between the two groups at 6 and 12 months (Fisher's exact test; P=0.574 and P=0.468, respectively).
  
  
  CONCLUSIONS
  NaOCl demonstrated clinical and radiographic success comparable to FC.
authors.affiliation: Department of Pediatric Dentistry, The University of Alabama at Birmingham, Birmingham, AL 35294, USA. john_ruby@cs1.dental.uab.edu
authors.forename: John D
authors.initials: JD
authors.lastname: Ruby
authors.forename: Charles F
authors.initials: CF
authors.lastname: Cox
authors.forename: Stephen C
authors.initials: SC
authors.lastname: Mitchell
authors.forename: Sonia
authors.initials: S
authors.lastname: Makhija
authors.forename: Papimon
authors.initials: P
authors.lastname: Chompu-Inwai
authors.forename: Janice
authors.initials: J
authors.lastname: Jackson
mesh_terms: D002648:Child; D002675:Child, Preschool; D003442:Crowns; D005260:Female; D005566:Formocresols / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008963:Molar / Q000601:surgery; D015588:Observer Variation; D057872:Pulp Capping and Pulpectomy Agents / Q000627:therapeutic use*; D011672:Pulpotomy / Q000379:methods*; D012390:Root Canal Therapy / Q000379:methods; D012973:Sodium Hypochlorite / Q000627:therapeutic use*; D018709:Statistics, Nonparametric; D014094:Tooth, Deciduous / Q000601:surgery*; D016896:Treatment Outcome
chemical_list: D005566:Formocresols; D057872:Pulp Capping and Pulpectomy Agents; C031025:formocresol; D012973:Sodium Hypochlorite