title: Development of tools to study lacto-N-biosidase: an important enzyme involved in the breakdown of human milk oligosaccharides.
abstract: Milk and sugar? The elucidation of the catalytic mechanism and the development of the first known inhibitor for lacto-N-biosidases, which are important enzymes involved in the breakdown of human milk oligosaccharides, are described.
authors.affiliation: School of Chemistry and Biochemistry, University of Western Australia, 35 Stirling Highway, Crawley, WA 6009, Australia.
authors.forename: Mitchell
authors.initials: M
authors.lastname: Hattie
authors.forename: Aleksandra W
authors.initials: AW
authors.lastname: Debowski
authors.forename: Keith A
authors.initials: KA
authors.lastname: Stubbs
mesh_terms: D050260:Carbohydrate Metabolism; D006026:Glycoside Hydrolases / Q000737:chemistry / Q000378:metabolism*; D006801:Humans; D007700:Kinetics; D007785:Lactose / Q000378:metabolism; D008895:Milk, Human / Q000201:enzymology* / Q000378:metabolism; D009844:Oligosaccharides / Q000737:chemistry / Q000378:metabolism*
chemical_list: D009844:Oligosaccharides; D006026:Glycoside Hydrolases; C076748:lacto-N-biosidase; D007785:Lactose