title: A 38-year old woman with a dural based lesion.
abstract: Isolated intracranial xanthogranulomas arising from the dura mater are extremely rare.We present a case of a symptomatic large right frontoparietal dura based intracranial xanthogranuloma in a 38-year-old female. Xanthogranulomas are benign non-Langerhans cell histiocytic lesions. They are frequently described in the skin of infants and children. Extracutaneous manifestations especially in the central nervous system are highly uncommon. Dural xanthogranulomas usually arise in association with familial hypercholesterolemia, with Erdheim Chester disease (ECD), and with Weber-Christian disease. Our case however, had no such associations. In this report, the authors describe the clinical, radiological and microscopic presentation of this case and the differential diagnoses of intracranial xanthogranuloma.
authors.forename: Sufia
authors.initials: S
authors.lastname: Husain
authors.forename: Hisham M S
authors.initials: HM
authors.lastname: Alkhalidi
authors.forename: Emad
authors.initials: E
authors.lastname: Raddaoui
mesh_terms: D000328:Adult; D001932:Brain Neoplasms / Q000473:pathology* / Q000601:surgery; D004388:Dura Mater / Q000473:pathology* / Q000601:surgery; D005260:Female; D005625:Frontal Lobe / Q000473:pathology* / Q000601:surgery; D006644:Histiocytes / Q000473:pathology; D015616:Histiocytosis, Non-Langerhans-Cell / Q000473:pathology* / Q000601:surgery; D006801:Humans; D010296:Parietal Lobe / Q000473:pathology* / Q000601:surgery; D016896:Treatment Outcome