title: Mechanisms of protein delivery to melanosomes in pigment cells.
abstract: Vertebrate pigment cells in the eye and skin are useful models for cell types that use specialized endosomal trafficking pathways to partition cargo proteins to unique lysosome-related organelles such as melanosomes. This review describes current models of protein trafficking required for melanosome biogenesis in mammalian melanocytes.
authors.affiliation: Cell and Molecular Biology Graduate Group, Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
authors.forename: Anand
authors.initials: A
authors.lastname: Sitaram
authors.forename: Michael S
authors.initials: MS
authors.lastname: Marks
mesh_terms: D000818:Animals; D011992:Endosomes / Q000378:metabolism; D006801:Humans; D008247:Lysosomes / Q000378:metabolism; D008543:Melanins / Q000378:metabolism; D008544:Melanocytes / Q000378:metabolism*; D020460:Melanosomes / Q000378:metabolism*; D021381:Protein Transport
chemical_list: D008543:Melanins