title: Clinical predictors of apnoea-hypopnoea during propofol sedation in patients undergoing spinal anaesthesia.
abstract: This study assessed the relationship between the occurrence of apnoea-hypopnoea during propofol sedation for spinal anaesthesia and two different predictive tests of sleep apnoea: the STOP-Bang score (snoring while sleeping, daytime tiredness, observed breathing stoppages, high blood pressure-body mass index, age, neck circumference, gender); and the obstructive sleep apnoea (OSA) score. Thirty-four middle-aged men not diagnosed with obstructive sleep apnoea received propofol infusions adjusted to produce a bispectral index of 70-75. ApnoeaLink(TM) was used to estimate the incidence of apnoea-hypopnoea. The median (IQR [range]) apnoea-hypopnoea index was 17 (8-24 [0-70]) events.h(-1) and correlated weakly with the STOP-Bang score (p = 0.022, r = 0.423) and moderately with the OSA score (p < 0.001, r = 0.693). Severe apnoea-hypopnoea developed more frequently in patients with a higher OSA score (34.5% vs 0%) or higher STOP-Bang score (27.6% vs 6.9%). Both assessment tools have some predictive value for the occurrence of apnoea-hypopnoea during propofol sedation in patients undergoing spinal anaesthesia.
authors.affiliation: Department of Anaesthesiology and Pain Medicine, National Medical Centre, Seoul, South Korea.
authors.forename: G H
authors.initials: GH
authors.lastname: Kim
authors.forename: J J
authors.initials: JJ
authors.lastname: Lee
authors.forename: S J
authors.initials: SJ
authors.lastname: Choi
authors.forename: B S
authors.initials: BS
authors.lastname: Shin
authors.forename: A R
authors.initials: AR
authors.lastname: Lee
authors.forename: S H
authors.initials: SH
authors.lastname: Lee
authors.forename: M H
authors.initials: MH
authors.lastname: Kim
mesh_terms: D000328:Adult; D000368:Aged; D000775:Anesthesia, Spinal / Q000009:adverse effects* / Q000379:methods; D016292:Procedural Sedation / Q000009:adverse effects* / Q000379:methods; D006801:Humans; D006993:Hypnotics and Sedatives / Q000009:adverse effects*; D007431:Intraoperative Complications / Q000139:chemically induced; D008297:Male; D008875:Middle Aged; D010808:Physical Examination / Q000379:methods; D011237:Predictive Value of Tests; D015742:Propofol / Q000009:adverse effects*; D011467:Prostate / Q000601:surgery; D012307:Risk Factors; D012720:Severity of Illness Index; D020181:Sleep Apnea, Obstructive / Q000139:chemically induced* / Q000175:diagnosis; D001743:Urinary Bladder / Q000601:surgery
chemical_list: D006993:Hypnotics and Sedatives; D015742:Propofol