title: A case of multiple giant coronary aneurysms and abdominal aortic aneurysm coexisting with IgG4-related disease.
abstract: IgG4-related disease (IgG4RD) is a unique systemic lymphoproliferative disorder characterized by elevated serum IgG4 levels and IgG4-producing plasma cell expansion in the affected tissues, which are accompanied by fibrotic or sclerotic changes. Vascular lesions may also be a part of IgG4RD as a number of case reports have discussed inflammatory abdominal aortic aneurysms associated with IgG4RD, but coronary artery lesions seem to be rare complications of IgG4RD. A 71-year-old man suffered from multiple giant coronary aneurysms and an abdominal aortic aneurysm with concurrent pancreatic, gall bladder, bile duct, and salivary gland lesions resulting from IgG4RD. The present observations suggest that coronary aneurysms may also develop as a consequence of this disease.
authors.affiliation: Department of Rheumatology and Clinical Immunology, Saitama Medical Center, Saitama Medical University, Japan.
authors.forename: Hirofumi
authors.initials: H
authors.lastname: Takei
authors.forename: Hayato
authors.initials: H
authors.lastname: Nagasawa
authors.forename: Ryota
authors.initials: R
authors.lastname: Sakai
authors.forename: Koji
authors.initials: K
authors.lastname: Nishimura
authors.forename: Takahiko
authors.initials: T
authors.lastname: Kurasawa
authors.forename: Ayumi
authors.initials: A
authors.lastname: Okuyama
authors.forename: Eiko
authors.initials: E
authors.lastname: Nishi
authors.forename: Yuichiro
authors.initials: Y
authors.lastname: Shirai
authors.forename: Tsuneo
authors.initials: T
authors.lastname: Kondo
authors.forename: Hiroe
authors.initials: H
authors.lastname: Ogawa
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Ito
authors.forename: Koichi
authors.initials: K
authors.lastname: Amano
mesh_terms: D000368:Aged; D017544:Aortic Aneurysm, Abdominal / Q000097:blood / Q000150:complications / Q000175:diagnosis*; D001327:Autoimmune Diseases / Q000097:blood / Q000150:complications / Q000175:diagnosis*; D003323:Coronary Aneurysm / Q000097:blood / Q000150:complications / Q000175:diagnosis*; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D008297:Male
chemical_list: D007074:Immunoglobulin G