title: Well-differentiated hepatocellular carcinoma detected as hypovascularity by only CT during hepatic arteriography.
abstract: We describe a well-differentiated hepatocellular carcinoma (HCC) with alcohol-related liver cirrhosis in a 69-year-old man. Ultrasonography (US) disclosed a 10 mm hypoechoic nodule in segment 4; Sonazoid contrast-enhanced US and gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid (Gd-EOB-DTPA)-enhanced magnetic resonance imaging (MRI) revealed no defect in either the Kupffer phase or the hepatobiliary phase. Computed tomography during hepatic arteriography (CTHA), however, revealed a hypovascular nodule, but CT during arterial portography showed no perfusion defect. Histological analysis indicated a well-differentiated HCC. Thus, our detection of well-differentiated HCC disclosed by only CTHA attested to the efficiency of this modality, suggesting that it is more sensitive than Gd-EOB-GTPA-enhanced MRI.
authors.affiliation: Department of Gastroenterology, Kobe Asahi Hospital, Japan.
authors.forename: Jun
authors.initials: J
authors.lastname: Saito
authors.forename: Soo Ryang
authors.initials: SR
authors.lastname: Kim
authors.forename: Masatoshi
authors.initials: M
authors.lastname: Kudo
authors.forename: Susumu
authors.initials: S
authors.lastname: Imoto
authors.forename: Kenji
authors.initials: K
authors.lastname: Ando
authors.forename: Taisuke
authors.initials: T
authors.lastname: Nakajima
authors.forename: Katsumi
authors.initials: K
authors.lastname: Fukuda
authors.forename: Yumi
authors.initials: Y
authors.lastname: Otono
authors.forename: Soo Ki
authors.initials: SK
authors.lastname: Kim
authors.forename: Takamitsu
authors.initials: T
authors.lastname: Komaki
authors.forename: Hirohisa
authors.initials: H
authors.lastname: Yano
authors.forename: Osamu
authors.initials: O
authors.lastname: Nakashima
authors.forename: Kayo
authors.initials: K
authors.lastname: Sugimoto
authors.forename: Toshiyuki
authors.initials: T
authors.lastname: Matsuoka
mesh_terms: D000368:Aged; D000792:Angiography / Q000592:standards; D006528:Carcinoma, Hepatocellular / Q000150:complications / Q000000981:diagnostic imaging*; D006801:Humans; D008104:Liver Cirrhosis, Alcoholic / Q000150:complications / Q000000981:diagnostic imaging*; D008113:Liver Neoplasms / Q000150:complications / Q000000981:diagnostic imaging*; D008297:Male; D014057:Tomography, X-Ray Computed / Q000592:standards*