title: ABO blood group and risk of pancreatic cancer in a Turkish population in Western Blacksea region.
abstract: BACKGROUND
  We aimed to investigate the relationship between blood groups and pancreatic cancer in a Turkish population in Western Blacksea region.
  
  
  METHODS
  This is a retrospective study. Zonguldak Karaelmas University outpatient oncology clinic records were screened for the period between 2004 and 2011.
  
  
  RESULTS
  The median age of patients were 56 (± 16) and 132 of 633 study population had pancreatic cancer. Pancreatic cancer patients had significantly higher rates of blood group A compared to controls (OR 1.8, 95%CI, p 0.005). Rates of blood group AB was significantly lower than the control group (OR 0.37, 95% CI, p 0.04). The median survival (IR) time in subjects having the blood groups A, B, AB and O were 7.0 (1-28), 7.0 (2-38), 10 (2-36) and 9.0 (2-48) months respectively; the blood group 0 had significantly higher overall survival (OS) compared to the non-0 groups (p 0.04).
  
  
  CONCLUSIONS
  Pancreatic cancer patients had more common blood group A in our population. Moreover, blood group AB appeared to be a protective factor against pancreatic cancer in our population. Blood group 0 had a significantly longer survival compared to non-0, regardless of prognostic factors.
authors.affiliation: Department of Oncology, Zonguldak Karaelmas University School of Medicine, Zonguldak, Turkey. bulengin@yahoo.com
authors.forename: Huseyin
authors.initials: H
authors.lastname: Engin
authors.forename: Cemil
authors.initials: C
authors.lastname: Bilir
authors.forename: Hasan
authors.initials: H
authors.lastname: Üstün
authors.forename: Ayla
authors.initials: A
authors.lastname: Gökmen
mesh_terms: D000017:ABO Blood-Group System; D016022:Case-Control Studies; D004198:Disease Susceptibility; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010190:Pancreatic Neoplasms / Q000453:epidemiology / Q000209:etiology* / Q000401:mortality* / Q000517:prevention & control; D011379:Prognosis; D012189:Retrospective Studies; D018570:Risk Assessment; D011795:Surveys and Questionnaires; D015996:Survival Rate; D014421:Turkey / Q000453:epidemiology
chemical_list: D000017:ABO Blood-Group System