title: Dioxygenation of the biphenyl dioxygenation product.
abstract: Two biphenyl dioxygenases (BphAs) were shown to catalyze dioxygenation of biphenyldienediol in the nonoxidized ring to form the respective symmetrical biphenyl-bis-dienediol. This novel metabolite served as a growth substrate for both BphA source strains. Its catabolism through the upper bph pathway of Burkholderia xenovorans LB400 was analyzed.
authors.affiliation: Department of Chemical Biology, Helmholtz Centre for Infection Research, Braunschweig, Germany.
authors.forename: Heike
authors.initials: H
authors.lastname: Overwin
authors.forename: Myriam
authors.initials: M
authors.lastname: González
authors.forename: Valentina
authors.initials: V
authors.lastname: Méndez
authors.forename: Michael
authors.initials: M
authors.lastname: Seeger
authors.forename: Victor
authors.initials: V
authors.lastname: Wray
authors.forename: Bernd
authors.initials: B
authors.lastname: Hofer
mesh_terms: D001713:Biphenyl Compounds / Q000378:metabolism*; D019117:Burkholderia / Q000201:enzymology* / Q000254:growth & development / Q000378:metabolism*; D002244:Carbon / Q000378:metabolism; D049308:Dioxygenases / Q000378:metabolism*; D004734:Energy Metabolism; D010084:Oxidation-Reduction
chemical_list: D001713:Biphenyl Compounds; D002244:Carbon; D049308:Dioxygenases