title: [Study on the chemical composition of triterpenoid from the fruit of Buddleja lindleyana and their neuroprotective activitiy].
abstract: OBJECTIVE
  To study the chemical composition of triterpenoid from the fruit of Buddleja lindleyana.
  
  
  METHODS
  The chemical components were isolated by chromatography. The structures were identified by spectral data. The neuroprotective activity of these compounds were evaluated by using MPP+ induced injury in PC12 cells.
  
  
  RESULTS
  3 compounds were separated and identified as oleanane, alpha-L-msnnopyranoside derive (1), 13, 28-epoxy-3beta,23-dihydroxy-11-oleanene (2), 3, 23, 28-trihydroxyolean-11,13 (18)-diene (3). Compounds 1-3 showed obviously neuroprotective activity.
  
  
  CONCLUSIONS
  The data of compound (1) is reported for the first time. The neuroprotective activities of compounds 1, 2, 3 are reported for the first time.
authors.affiliation: Department of Pharmacy, Anhui College of Traditional Chinese Medicine, Hefei 230031, China. dlwu7375@sina.com
authors.forename: De-Ling
authors.initials: DL
authors.lastname: Wu
authors.forename: Yang-Kui
authors.initials: YK
authors.lastname: Wang
authors.forename: Xun-Cui
authors.initials: XC
authors.lastname: Wang
authors.forename: Jin-Song
authors.initials: JS
authors.lastname: Liu
authors.forename: Chuan-Shan
authors.initials: CS
authors.lastname: Jin
authors.forename: Wei
authors.initials: W
authors.lastname: Zhang
mesh_terms: D000818:Animals; D032861:Buddleja / Q000737:chemistry*; D002470:Cell Survival / Q000187:drug effects; D005638:Fruit / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D018696:Neuroprotective Agents / Q000302:isolation & purification / Q000494:pharmacology*; D016716:PC12 Cells; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D010946:Plants, Medicinal / Q000737:chemistry; D051381:Rats; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: D018696:Neuroprotective Agents; D010936:Plant Extracts; D014315:Triterpenes