title: Hantavirus pulmonary syndrome: Report of four Alberta cases.
abstract: Four Alberta cases of hantavirus pulmonary syndrome are reported. Three cases required intensive care, with one experiencing a fulminant course resulting in death. A fourth case with milder illness was identified after epidemiological investigations. Ribavirin was used in one patient who experienced a successful outcome. A recent open label trial has not supported the efficacy of this drug. The epidemiology of Peromyscus maniculatus, the primary rodent host, and the clinical features of this syndrome are summarized.
authors.affiliation: Division of Infectious Diseases, University of Alberta, Edmonton, Alberta, and British Columbia Centre for Disease Control, Vancouver, British Columbia.
authors.forename: A E
authors.initials: AE
authors.lastname: Singh
authors.forename: D H
authors.initials: DH
authors.lastname: Werker
authors.forename: L R
authors.initials: LR
authors.lastname: Boychuk
authors.forename: L J
authors.initials: LJ
authors.lastname: Miedzinski