title: Molecular characterization and antifungal susceptibility of the Candida parapsilosis species complex of clinical isolates from Monterrey, Mexico.
abstract: Recently, it was proposed that the opportunistic yeast pathogen Candida parapsilosis was a complex composed of the following three species: Candida parapsilosis sensu stricto, Candida orthopsilosis, and Candida metapsilosis. A set of 344 clinical isolates of Candida parapsilosis from Monterrey, Mexico was re-identified by RFLP. Their antifungal susceptibility to fluconazole, caspofungin, anidulafungin and micafungin was determined using the Clinical and Laboratory Standards Institute M27-A3 protocol. Candida parapsilosis sensu stricto was the most frequent species, and was the only one which showed resistance to antifungals.
authors.affiliation: Departamento de Microbiología, Facultad de Medicina, Universidad Autónoma de Nuevo León , Monterrey, Nuevo León, México.
authors.forename: Rogelio De J
authors.initials: Rde J
authors.lastname: Treviño-Rangel
authors.forename: Elvira
authors.initials: E
authors.lastname: Garza-González
authors.forename: J Gerardo
authors.initials: JG
authors.lastname: González
authors.forename: Virgilio
authors.initials: V
authors.lastname: Bocanegra-García
authors.forename: Jorge M
authors.initials: JM
authors.lastname: Llaca
authors.forename: Gloria M
authors.initials: GM
authors.lastname: González
mesh_terms: D000935:Antifungal Agents / Q000494:pharmacology*; D002175:Candida / Q000145:classification* / Q000187:drug effects* / Q000235:genetics / Q000302:isolation & purification; D002177:Candidiasis / Q000453:epidemiology* / Q000382:microbiology*; D016172:DNA Fingerprinting; D004271:DNA, Fungal / Q000235:genetics; D025141:Drug Resistance, Fungal; D014644:Genetic Variation; D006801:Humans; D008800:Mexico / Q000453:epidemiology; D008826:Microbial Sensitivity Tests; D012150:Polymorphism, Restriction Fragment Length
chemical_list: D000935:Antifungal Agents; D004271:DNA, Fungal