title: Spectral-domain optical coherence tomography in uveitic macular edema: morphological features and prognostic factors.
abstract: OBJECTIVE
  To assess the morphological characteristics of uveitic macular edema studied with Spectralis optical coherence tomography (OCT) and to investigate the correlation between the tomographic features and visual acuity.
  
  
  METHODS
  71 eyes of 55 patients underwent examination with Spectralis OCT (Heidelberg Engineering, Germany). Data was correlated with logMAR best-corrected visual acuity (BCVA).
  
  
  RESULTS
  Two morphological patterns were observed: cystoid macular edema (CME) in 69% and diffuse macular edema in 31% of eyes. BCVA was 0.2 in CME, 0.1 in diffuse edema (p = 0.008). Foveal thickness was 413.4 ± 212 µm in CME, 311.27 ± 53 µm in diffuse edema (p = 0.03). BVCA was 0.3 in eyes with serous retinal detachment (SRD), 0.2 in eyes without SRD (p = 0.02). BCVA was 0.4 in eyes with inner segment/outer segment (IS/OS) disruption, 0.1 in eyes with integrity of the IS/OS junction (p = 0.01).
  
  
  CONCLUSIONS
  BCVA is negatively correlated with cystoid pattern, foveal thickening and SRD. Disruption of the IS/OS junction is associated with poor vision in uveitic macular edema.
authors.affiliation: Department of Ophthalmology, Sapienza University of Rome, Rome, Italy. l.iannetti @ policlinicoumberto1.it
authors.forename: Ludovico
authors.initials: L
authors.lastname: Iannetti
authors.forename: Giovanni
authors.initials: G
authors.lastname: Spinucci
authors.forename: Alessandro
authors.initials: A
authors.lastname: Abbouda
authors.forename: Daniele
authors.initials: D
authors.lastname: De Geronimo
authors.forename: Paolo
authors.initials: P
authors.lastname: Tortorella
authors.forename: Massimo
authors.initials: M
authors.lastname: Accorinti
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D005260:Female; D006801:Humans; D008269:Macular Edema / Q000175:diagnosis* / Q000209:etiology / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012189:Retrospective Studies; D041623:Tomography, Optical Coherence; D014605:Uveitis / Q000150:complications*; D014792:Visual Acuity / Q000502:physiology; D055815:Young Adult