title: [Ultrasound guided implantation of radioactive (125)I seeds for treatment of recurrent head and neck carcinomas].
abstract: OBJECTIVE
  To evaluate the efficacy and the technological feasibility of B-ultrasound guided implantation of (125)I seed for recurrent head and neck  cancer.
  
  
  METHODS
  In the study, 29 patients with local or regional recurrence of head and neck tumors after external beam radiotherapy alone, external  beam radiotherapy combined neck dissection or chemotherapy were treated with (125)I seed implantation guided by ultrasound under local anesthesia.  The median number of seeds was 27 (ranging from 3 to 61), and the radioactive activity ranged from 0.35-0.8 mCi(1.30×10(7) -2.96×10(7) Bq). Postoperative  quality evaluations were routinely obtained for all the patients.
  
  
  RESULTS
  The median follow-up was 8 months (ranging from 3 to 42 months). The 1-, 2- and 3-year local controls were 53.1%, 34.8%, and 17.4%, respectively. The 1-, 2- and 3-year survival rates were 54.1%, 27.5%, and 27.5%,  respectively.
  
  
  CONCLUSIONS
  Ultrasound guided implantation of (125)I  seeds can play an important role in the salvage treatment of recurrence of head and  neck cancer. This study shows B-ultrasound guided (125)I  seed implantation is one of the most efficient brachytherapies, which is easy to operate, least  invasive and safe for low morbidity.
authors.affiliation: Department of Radiation Oncology, Peking University Third Hospital, Beijing  100191, China.
authors.forename: Ping
authors.initials: P
authors.lastname: Jiang
authors.forename: Yue
authors.initials: Y
authors.lastname: Ma
authors.forename: Jun-jie
authors.initials: JJ
authors.lastname: Wang
authors.forename: Wei-qiang
authors.initials: WQ
authors.lastname: Ran
authors.forename: Yu Liang
authors.initials: YL
authors.lastname: Jiang
authors.forename: Ang
authors.initials: A
authors.lastname: Qu
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001918:Brachytherapy / Q000379:methods*; D002294:Carcinoma, Squamous Cell / Q000000981:diagnostic imaging / Q000532:radiotherapy; D005260:Female; D006258:Head and Neck Neoplasms / Q000000981:diagnostic imaging / Q000532:radiotherapy*; D006801:Humans; D007457:Iodine Radioisotopes / Q000008:administration & dosage*; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000000981:diagnostic imaging / Q000532:radiotherapy*; D061089:Radiotherapy, Image-Guided / Q000379:methods; D014463:Ultrasonography / Q000379:methods; D055815:Young Adult
chemical_list: D007457:Iodine Radioisotopes