title: Phytoestrogens for menopausal symptoms: a review.
abstract: OBJECTIVE
  To review the evidence that isoflavones are effective treatments for menopausal symptoms and to present the safety data.
  
  
  METHODS
  The databases Scopus, ScienceDirect and Primo Central Index were searched and preference was given to systematic reviews and meta-analyses.
  
  
  RESULTS
  The available evidence suggests that isoflavones do not relieve menopausal vasomotor symptoms any better than placebo. Long-term safety studies suggest that women who consume a diet high in isoflavones may have a lower risk of endometrial and ovarian cancer.
  
  
  CONCLUSIONS
  Isoflavones cannot be recommended for the relief of hot flushes.
authors.affiliation: School of Women and Children's Health, University of NSW, Randwick, NSW 2031, Australia. j.eden@unsw.edu.au
authors.forename: John A
authors.initials: JA
authors.lastname: Eden
mesh_terms: D001943:Breast Neoplasms / Q000453:epidemiology; D005260:Female; D019584:Hot Flashes / Q000188:drug therapy / Q000517:prevention & control; D006801:Humans; D007529:Isoflavones / Q000009:adverse effects / Q000494:pharmacology / Q000627:therapeutic use; D008593:Menopause / Q000187:drug effects* / Q000502:physiology; D008875:Middle Aged; D048789:Phytoestrogens / Q000009:adverse effects / Q000494:pharmacology* / Q000627:therapeutic use; D012307:Risk Factors
chemical_list: D007529:Isoflavones; D048789:Phytoestrogens