title: Acitretin in management of diffuse common warts: a case report.
abstract: Warts are among the most commonly observed dermatological diseases, caused by human papilloma virus (HPV), usually HPV1-2 subtypes; HPV4-7 are rarely found and mostly related to professional exposure (butchers and dairy workers). Different therapeutical approaches are possible, depending on extension and severity of lesions. The present authors describe the case of 32-year-old Caucasian man, who came to our attention for the presence of numerous exophytic papules on the back of both hands and over periungual regions, which appeared about 6 months before. Histological examination confirmed the clinical suspicion of common warts (HPV4). The patient underwent therapy by acitretin for 12 weeks, obtaining during the 8th week of therapy complete resolution of skin lesions. The present authors present this case for the unusual local aggressiveness of viral warts in an immunocompetent patient successfully treated with acitetrin.
authors.affiliation: Department of Dermatology "Daniele Innocenzi," University of Rome "Sapienza," Polo Pontino, Italy.
authors.forename: Ilaria
authors.initials: I
authors.lastname: Proietti
authors.forename: Nevena
authors.initials: N
authors.lastname: Skroza
authors.forename: Nicoletta
authors.initials: N
authors.lastname: Bernardini
authors.forename: Francesca
authors.initials: F
authors.lastname: Nicolucci
authors.forename: Ersilia
authors.initials: E
authors.lastname: Tolino
authors.forename: Giorgio
authors.initials: G
authors.lastname: La Viola
authors.forename: Diego
authors.initials: D
authors.lastname: Orsini
authors.forename: Sara
authors.initials: S
authors.lastname: Zuber
authors.forename: Concetta
authors.initials: C
authors.lastname: Potenza
mesh_terms: D017255:Acitretin / Q000008:administration & dosage / Q000627:therapeutic use*; D000284:Administration, Oral; D000328:Adult; D052689:Gammapapillomavirus / Q000302:isolation & purification; D006229:Hand Dermatoses / Q000188:drug therapy* / Q000473:pathology / Q000821:virology; D006801:Humans; D007641:Keratolytic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D008297:Male; D016896:Treatment Outcome; D014860:Warts / Q000188:drug therapy* / Q000473:pathology / Q000821:virology
chemical_list: D007641:Keratolytic Agents; D017255:Acitretin