title: Controlling the formation of DNA origami structures with external signals.
abstract: Degradable Newkome-type and polylysine dendrons functionalized with spermine surface units are used to control the formation of DNA origami structures. The intact dendrons form polyelectrolyte complexes with the scaffold strands, therefore blocking the origami formation. Degradation of the dendron with an optical trigger or chemical reduction leads to the release of the DNA scaffold and efficient formation of the desired origami structure. These results provide new insights towards realizing responsive materials with DNA origami.
authors.affiliation: Department of Applied Physics, Aalto University, 6 Aalto University, Finland.
authors.forename: Antti-Pekka
authors.initials: AP
authors.lastname: Eskelinen
authors.forename: Henna
authors.initials: H
authors.lastname: Rosilo
authors.forename: Anton
authors.initials: A
authors.lastname: Kuzyk
authors.forename: Päivi
authors.initials: P
authors.lastname: Törmä
authors.forename: Mauri A
authors.initials: MA
authors.lastname: Kostiainen
mesh_terms: D004247:DNA / Q000737:chemistry*; D050091:Dendrimers / Q000737:chemistry*; D036103:Nanotechnology / Q000379:methods*; D009690:Nucleic Acid Conformation
chemical_list: D050091:Dendrimers; D004247:DNA