title: [Carcinomatous meningitis in a post-operative patient with lung adenocarcinoma for which erlotinib was effective - a case report].
abstract: A 53-year-old female was admitted to our hospital complaining of disturbance of consciousness and hallucinations. About one year and 5 months ago she had adenocarcinoma of the lung, which was treated with surgery and chemotherapy. Computed tomography and magnetic resonance imaging revealed that her lung cancer had relapsed as caricinomatous meningitis and multiple lung metastases. She was treated with erlotinib, which rapidly resulted in disappearance of her symptoms. She still continues to receive erlotinib therapy without suffering from evident relapse 7 months after the initiation of the treatment.
authors.affiliation: Dept. of Respiratology Medicine, Osaka City University.
authors.forename: Masahiro
authors.initials: M
authors.lastname: Manabe
authors.forename: Shigeki
authors.initials: S
authors.lastname: Mitsuoka
authors.forename: Kanako
authors.initials: K
authors.lastname: Umekawa
authors.forename: Hidenori
authors.initials: H
authors.lastname: Tanaka
authors.forename: Tatsuo
authors.initials: T
authors.lastname: Kimura
authors.forename: Naruo
authors.initials: N
authors.lastname: Yoshimura
authors.forename: Akitoshi
authors.initials: A
authors.lastname: Takeda
authors.forename: Shinzoh
authors.initials: S
authors.lastname: Kudoh
authors.forename: Kazuto
authors.initials: K
authors.lastname: Hirata
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D000077192:Adenocarcinoma of Lung; D000069347:Erlotinib Hydrochloride; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D055756:Meningeal Carcinomatosis; D008875:Middle Aged; D009367:Neoplasm Staging; D047428:Protein Kinase Inhibitors / Q000627:therapeutic use*; D011799:Quinazolines / Q000627:therapeutic use*
chemical_list: D047428:Protein Kinase Inhibitors; D011799:Quinazolines; D000069347:Erlotinib Hydrochloride