title: Determination of crossed language dominance: dissociation of language lateralization within the temporoparietal cortex.
abstract: 'Crossed language dominance' is a rare form of language lateralization, characterized by a dissociation of anterior and posterior language regions. We present the case of a healthy subject whose language lateralization pattern, as assessed by functional magnetic resonance imaging, is reliably characterized as crossed language dominance based on a word generation task, but typical left-lateralized when a semantic decision task is applied. A single language task is therefore not sufficient to characterize language lateralization, at least not for subjects with rare forms of language dominance. In the pre-surgical diagnostic of language lateralization, several language tasks tapping into different aspects of language functions should be applied.
authors.affiliation: Department of Psychiatry and Psychotherapy, Philipps-University Marburg, Marburg, Germany. jansena@med.uni-marburg.de
authors.forename: Andreas
authors.initials: A
authors.lastname: Jansen
authors.forename: Stephanie
authors.initials: S
authors.lastname: Müller
authors.forename: Johannes
authors.initials: J
authors.lastname: Bedenbender
authors.forename: Sören
authors.initials: S
authors.lastname: Krach
authors.forename: Frieder M
authors.initials: FM
authors.lastname: Paulus
authors.forename: Tilo
authors.initials: T
authors.lastname: Kircher
authors.forename: Jens
authors.initials: J
authors.lastname: Sommer
mesh_terms: D000328:Adult; D002540:Cerebral Cortex / Q000098:blood supply / Q000502:physiology*; D007839:Functional Laterality / Q000502:physiology*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007802:Language; D008279:Magnetic Resonance Imaging; D008297:Male; D010100:Oxygen / Q000097:blood
chemical_list: D010100:Oxygen