title: Acceptor-influenced and donor-tuned base-promoted glycosylation.
abstract: Base-promoted glycosylation is a recently established stereoselective and regioselective approach for the assembly of di- and oligosaccharides by using partially protected acceptors and glycosyl halide donors. Initial studies were performed on partially methylated acceptor and donor moieties as a model system in order to analyze the key principles of oxyanion reactivities. In this work, extended studies on base-promoted glycosylation are presented by using benzyl protective groups in view of preparative applications. Emphases are placed on the influence of the acceptor anomeric configuration and donor reactivities.
authors.affiliation: Department of Chemistry, Faculty of Science, University of Hamburg, Martin-Luther-King-Platz 6, 20146 Hamburg, Germany.
authors.forename: Stephan
authors.initials: S
authors.lastname: Boettcher
authors.forename: Martin
authors.initials: M
authors.lastname: Matwiejuk
authors.forename: Joachim
authors.initials: J
authors.lastname: Thiem