title: Designing chimeric LOV photoswitches.
abstract: The LOV domain from Avena sativa has a C-terminal (Jα) helix that dissociates and unfolds when the protein is exposed to blue light. Using computational protein design methods, Lungu et al., in this issue of Chemistry & Biology, created chimeric Jα sequences that show photo-controlled interactions with chosen targets.
authors.affiliation: Department of Chemistry, University of Toronto, 80 St. George Street, Toronto, ON M5S 3H6, Canada. awoolley@chem.utoronto.ca
authors.forename: G Andrew
authors.initials: GA
authors.lastname: Woolley