title: Coronary surgery in a hemophiliac with continuous factor VIII replacement.
abstract: In the past, hemophiliacs rarely underwent cardiac surgery because of limited lifespan. As blood transfusions have become safer, hemophiliacs are living longer and becoming more susceptible to diseases that afflict the elderly, such as coronary atherosclerosis. We describe the hematologic management of a patient with hemophilia A who underwent coronary artery bypass surgery.
authors.affiliation: Division of Cardiothoracic Surgery, Department of Cardiovascular Sciences, Brody School of Medicine, East Carolina University, 600 Moye Blvd, Greenville, NC 27834, USA. kypsona@ecu.edu
authors.forename: Alan P
authors.initials: AP
authors.lastname: Kypson
authors.forename: Evelio
authors.initials: E
authors.lastname: Rodriguez
authors.forename: Curtis A
authors.initials: CA
authors.lastname: Anderson
mesh_terms: D060050:Angina, Stable / Q000150:complications / Q000175:diagnosis / Q000601:surgery*; D001777:Blood Coagulation / Q000187:drug effects*; D016063:Blood Loss, Surgical / Q000517:prevention & control; D006328:Cardiac Catheterization; D002315:Cardiopulmonary Bypass; D003029:Coagulants / Q000008:administration & dosage*; D001026:Coronary Artery Bypass / Q000379:methods*; D004305:Dose-Response Relationship, Drug; D005169:Factor VIII / Q000008:administration & dosage / Q000378:metabolism*; D005500:Follow-Up Studies; D006467:Hemophilia A / Q000097:blood / Q000150:complications*; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D008875:Middle Aged; D019106:Postoperative Hemorrhage / Q000517:prevention & control
chemical_list: D003029:Coagulants; C078147:F8 protein, human; D005169:Factor VIII