title: [Analysis on the diagnosis and treatment of a cluster of cases infected by new bunyavirus].
abstract: OBJECTIVE
  To analyze and summarize the clinical characteristics, experience of diagnosis and treatment of cases infected by new bunyavirus, which occurred in Henan province in 2010.
  
  
  METHODS
  The clinical characteristics and effect of diagnosis and treatment of 5 cases were analyzed using descriptive epidemiological method. Blood specimens were detected by RT-PCR and pathogen separation.
  
  
  RESULTS
  PCR testing was positive for all 5 cases. New bunyavirus were isolated from 2 cases. In 5 cases, fever (5/5), the whole body aches (5/5), fatigue (5/5), anorexia (5/5), nausea (5/5), the chills (4/5), cough (4/5), expectoration (4/5), vomiting (3/5), conjunctival hyperemia (3/5); Leukocyte reduction (5/5), thrombocytopenia (5/5), elevated alanine aminotransferase (4/5), elevated aspartate aminotransferase (4/5), elevated lactate dehydrogenase (5/5), creatine kinase elevations (4/5), urinary protein (3/5). By symptomatic and supportive treatment and prophylactic antibiotics, the first case died and the other 4 cases were cured. The average course of disease was 15.4 days.
  
  
  CONCLUSIONS
  Cases infected by new bunyavirus have complicated clinical feature and multiple organ damage. If symptomatic treatment is in time, prognosis will be good.
authors.affiliation: Institute for Infectious Disease Control and Prevention, Henan Provincial Center for Disease Control and Prevention, Zhengzhou 450016, China.
authors.forename: Xiao-Yan
authors.initials: XY
authors.lastname: Tang
authors.forename: Ning
authors.initials: N
authors.lastname: Cui
authors.forename: Kai
authors.initials: K
authors.lastname: Kang
authors.forename: Hai-Feng
authors.initials: HF
authors.lastname: Wang
authors.forename: Ai-Guo
authors.initials: AG
authors.lastname: You
authors.forename: Guo-Hua
authors.initials: GH
authors.lastname: Zhao
authors.forename: Jia-Qiang
authors.initials: JQ
authors.lastname: Yang
authors.forename: Xue-Yong
authors.initials: XY
authors.lastname: Huang
authors.forename: Yan-Hua
authors.initials: YH
authors.lastname: DU
authors.forename: Hao-Min
authors.initials: HM
authors.lastname: Chen
authors.forename: Guo-Hua
authors.initials: GH
authors.lastname: Liu
authors.forename: Bian-Li
authors.initials: BL
authors.lastname: Xu
mesh_terms: D000328:Adult; D002044:Bunyaviridae Infections / Q000175:diagnosis* / Q000628:therapy* / Q000821:virology; D002681:China / Q000453:epidemiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016851:Orthobunyavirus; D011379:Prognosis; D055815:Young Adult