title: Functionalized Fe3O4 nanoparticles for detecting zinc ions in living cells and their cytotoxicity.
abstract: The zinc tank: A new fluoro-chromogenic chemosensor based on BODIPY-functionalized Fe(3)O(4) nanoparticles (1) has been prepared. Chemoprobe 1 exhibits high selectivity for Zn(2+) over other competing metal ions tested. Moreover, confocal microscopy experiments established that 1 can be used for detecting Zn(2+) levels in living cells (see figure).
authors.affiliation: Department of Chemistry and Research Institute of Natural Sciences Gyeongsang National University, Jinju 660-701, Korea.
authors.forename: Gyusik
authors.initials: G
authors.lastname: Kang
authors.forename: Hyunjong
authors.initials: H
authors.lastname: Son
authors.forename: Jung Mi
authors.initials: JM
authors.lastname: Lim
authors.forename: Hee-Seek
authors.initials: HS
authors.lastname: Kweon
authors.forename: In Soo
authors.initials: IS
authors.lastname: Lee
authors.forename: Dongmin
authors.initials: D
authors.lastname: Kang
authors.forename: Jong Hwa
authors.initials: JH
authors.lastname: Jung
mesh_terms: D001896:Boron Compounds / Q000737:chemistry; D052203:Ferrosoferric Oxide / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000138:chemical synthesis* / Q000737:chemistry; D006367:HeLa Cells; D006801:Humans; D015394:Molecular Structure; D053758:Nanoparticles / Q000737:chemistry*; D015032:Zinc / Q000032:analysis*
chemical_list: C095489:4,4-difluoro-4-bora-3a,4a-diaza-s-indacene; D001896:Boron Compounds; D005456:Fluorescent Dyes; D015032:Zinc; D052203:Ferrosoferric Oxide