title: NGF-p75 and neuropsin/KLK8 pathways stimulate each other to cause hyperkeratosis and acanthosis in inflamed skin.
authors.forename: Kenta
authors.initials: K
authors.lastname: Shingaki
authors.forename: Manabu
authors.initials: M
authors.lastname: Taniguchi
authors.forename: Shigeyuki
authors.initials: S
authors.lastname: Kanazawa
authors.forename: Shinsuke
authors.initials: S
authors.lastname: Matsuzaki
authors.forename: Tameyasu
authors.initials: T
authors.lastname: Maeda
authors.forename: Shingo
authors.initials: S
authors.lastname: Miyata
authors.forename: Tateki
authors.initials: T
authors.lastname: Kubo
authors.forename: Kosuke
authors.initials: K
authors.lastname: Torii
authors.forename: Sadao
authors.initials: S
authors.lastname: Shiosaka
authors.forename: Masaya
authors.initials: M
authors.lastname: Tohyama
mesh_terms: D000818:Animals; D002460:Cell Line; D003872:Dermatitis / Q000209:etiology / Q000235:genetics / Q000378:metabolism* / Q000473:pathology; D004195:Disease Models, Animal; D004817:Epidermis / Q000378:metabolism* / Q000473:pathology; D005786:Gene Expression Regulation; D006801:Humans; D007610:Kallikreins / Q000172:deficiency / Q000235:genetics / Q000378:metabolism*; D015603:Keratinocytes / Q000378:metabolism; D007642:Keratosis / Q000139:chemically induced / Q000235:genetics / Q000378:metabolism* / Q000473:pathology; D008548:Melanosis / Q000139:chemically induced / Q000235:genetics / Q000378:metabolism* / Q000473:pathology; D051379:Mice; D008810:Mice, Inbred C57BL; D018345:Mice, Knockout; D020932:Nerve Growth Factor / Q000378:metabolism*; D034622:RNA Interference; D012333:RNA, Messenger / Q000378:metabolism; D060888:Real-Time Polymerase Chain Reaction; D017475:Receptors, Nerve Growth Factor / Q000172:deficiency / Q000235:genetics / Q000378:metabolism*; D012967:Sodium Dodecyl Sulfate; D014162:Transfection
chemical_list: C502240:NGF protein, human; D012333:RNA, Messenger; D017475:Receptors, Nerve Growth Factor; C517634:Ngfr protein, mouse; D012967:Sodium Dodecyl Sulfate; D020932:Nerve Growth Factor; C094799:KLK8 protein, human; D007610:Kallikreins; C114664:Prss19 protein, mouse