title: Structural studies on ionic liquid/water/peptide systems by HR-MAS NMR spectroscopy.
abstract: The present work reports on an assessment of high-resolution magic angle spinning (HR-MAS) NMR spectroscopy for structural investigations of peptides dissolved in aqueous ionic liquids. Highly resolved one- and two-dimensional NMR spectra are obtained that allow for complete proton resonance assignments of both the peptides as solutes and the ionic liquids as solvents. Successful application of the HR-MAS method facilitates for the first time high-resolution NMR analysis of complex ionic liquid/peptide systems at the molecular level, mainly on the basis of chemical-shift changes.
authors.affiliation: Institute of Biochemistry and Biotechnology, Martin-Luther-University Halle-Wittenberg, Kurt-Mothes-Str. 3, 06120 Halle, Germany. mrestani-klaus@biochemtech.uni-halle.de
authors.forename: Carmen
authors.initials: C
authors.lastname: Mrestani-Klaus
authors.forename: Annekathrin
authors.initials: A
authors.lastname: Richardt
authors.forename: Christian
authors.initials: C
authors.lastname: Wespe
authors.forename: Annegret
authors.initials: A
authors.lastname: Stark
authors.forename: Eberhard
authors.initials: E
authors.lastname: Humpfer
authors.forename: Frank
authors.initials: F
authors.lastname: Bordusa
mesh_terms: D052578:Ionic Liquids / Q000737:chemistry*; D019906:Nuclear Magnetic Resonance, Biomolecular; D009842:Oligopeptides / Q000737:chemistry*; D012997:Solvents; D014867:Water / Q000737:chemistry*
chemical_list: D052578:Ionic Liquids; D009842:Oligopeptides; D012997:Solvents; D014867:Water