title: Oocyte cryopreservation following failed testicular sperm extraction: a French case report with implications for the management of non-obstructive azoospermia.
abstract: The French law regulating assisted reproductive technologies forbids donor spermatozoa to be available in case of failed testicular sperm extraction (TESE) performed on the day of oocyte retrieval. This article reports the first French live birth after intracytoplasmic sperm injection of donated spermatozoa into frozen-thawed oocytes cryopreserved following failure of TESE. By reinforcing the relevance of TESE performed on the day of oocyte retrieval, oocyte cryopreservation in couples having beforehand consented to go to sperm donation will avoid cycle cancellation and potentially lead to successful live birth. Therefore, it could modify the French policy of management of patients suffering from non-obstructive azoospermia.
authors.affiliation: AP-HP, Service de Gynécologie-Obstétrique et Médecine de la Reproduction, Hôpital Antoine Béclère, Clamart F-92141, France. michael.grynberg@abc.aphp.fr
authors.forename: Michaël
authors.initials: M
authors.lastname: Grynberg
authors.forename: Laetitia
authors.initials: L
authors.lastname: Hesters
authors.forename: Thibault
authors.initials: T
authors.lastname: Thubert
authors.forename: Vincent
authors.initials: V
authors.lastname: Izard
authors.forename: Renato
authors.initials: R
authors.lastname: Fanchin
authors.forename: René
authors.initials: R
authors.lastname: Frydman
authors.forename: Nelly
authors.initials: N
authors.lastname: Frydman
mesh_terms: D000328:Adult; D053713:Azoospermia / Q000628:therapy*; D015925:Cryopreservation; D005260:Female; D005602:France; D006801:Humans; D008297:Male; D009865:Oocytes; D010062:Ovulation Induction; D011247:Pregnancy; D011256:Pregnancy Outcome; D027724:Reproductive Techniques, Assisted / Q000331:legislation & jurisprudence; D020554:Sperm Injections, Intracytoplasmic / Q000331:legislation & jurisprudence*; D053625:Sperm Retrieval / Q000331:legislation & jurisprudence*; D016896:Treatment Outcome