title: [Effects of different altitudes on cardiac hemodynamics and electrocardiogram of healthy male adults].
abstract: OBJECTIVE
  To detect the changes of cardiovascular system at different altitudes, so as to prevent and predict the susceptibility to acute mountain sickness.
  
  
  METHODS
  The test was performed with noninvasive cardiovascular monitor and electrocardiogram in healthy male Chinese members of the 25th and 26th expeditions to the antarctic kunlun station at different altitudes (40 m, 3 650 m and 4 300 m).
  
  
  RESULTS
  Compared with 40 m, from 3 650 m to 4 300 m, heart rate (HR), systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), systemic vascular resistance (SVR), systemic vascular resistance index (SVRI) significantly increased (P < 0.05); cardiac output (CO), cardiac index (CI), stroke volume (SV), stroke index (SI), velocity index (VI), acceleration index (ACI), left ventricular ejection time (LVET) significantly decreased (P < 0.05) and pre-ejection period(PEP) decreased with no significance (P > 0.05).
  
  
  CONCLUSIONS
  SVR significantly increased but contractile and blood-pumping function of left ventricular decreased inversely associated with the Q-Tc interval, as the altitude is increasing.
authors.affiliation: Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Beijing 100005, China.
authors.forename: Zheng-Min
authors.initials: ZM
authors.lastname: Guo
authors.forename: Fu-Min
authors.initials: FM
authors.lastname: Huang
authors.forename: Hui
authors.initials: H
authors.lastname: Lu
authors.forename: Shu-Yu
authors.initials: SY
authors.lastname: Zu
authors.forename: Cheng-Li
authors.initials: CL
authors.lastname: Xu
mesh_terms: D000328:Adult; D000531:Altitude; D002302:Cardiac Output; D004562:Electrocardiography; D006339:Heart Rate; D006439:Hemodynamics; D006801:Humans; D000860:Hypoxia; D008297:Male