title: Effect of signalment on the presentation of canine patients suffering from cranial cruciate ligament disease.
abstract: OBJECTIVE
  To determine the effect of signalment on the incidence and presentation of patients suffering from cranial cruciate ligament disease.
  
  
  METHODS
  Data relating to 426 dogs (44 breeds) that met specific selection criteria were obtained from the hospital archive (2002 to 2008). Cases were followed up for 2 years.
  
  
  RESULTS
  The breeds most commonly presented with cranial cruciate ligament disease were Labrador retriever (16%), Rottweiler (15%), golden retriever (12%) and boxer (9%). Rottweilers were significantly more likely (69%; P=0·05) to develop and present with (50%; P=0·03) bilateral cranial cruciate ligament disease. Rottweilers presenting with cranial cruciate ligament disease were significantly younger (median 977 days; P<0·0001) than other breeds; golden retrievers being significantly older at presentation (median 1994 days; P=0·004). Neither sex nor neutered status significantly affected the incidence of developing (P=0·77 and P=0·30, respectively) or presenting with (P=0·62 and P=0·35, respectively) bilateral cranial cruciate ligament disease. Entire dogs were significantly younger than neutered dogs at presentation (P=0·0004). Entire female dogs presented significantly younger than neutered females (P=0·0002), entire males (P=0·01) and neutered males (P=0·0001).
  
  
  CONCLUSIONS
  Breed affects the incidence of developing and presenting with bilateral cranial cruciate ligament disease. Breed and sex both affect the age that patients present with cranial cruciate ligament disease.
authors.affiliation: Northwest Surgeons, Delamere House, Ashville Point, Sutton Weaver, Cheshire WA7 3FW.
authors.forename: J W
authors.initials: JW
authors.lastname: Guthrie
authors.forename: B J
authors.initials: BJ
authors.lastname: Keeley
authors.forename: E
authors.initials: E
authors.lastname: Maddock
authors.forename: S R
authors.initials: SR
authors.lastname: Bright
authors.forename: C
authors.initials: C
authors.lastname: May
mesh_terms: D000367:Age Factors; D000818:Animals; D016118:Anterior Cruciate Ligament / Q000473:pathology*; D001947:Breeding; D016022:Case-Control Studies; D004283:Dog Diseases / Q000453:epidemiology* / Q000473:pathology*; D004285:Dogs; D005260:Female; D008297:Male; D012737:Sex Factors; D013264:Stifle / Q000473:pathology*