title: [Basic research progress of knee osteoarthritis].
abstract: The exact etiology and pathogenesis of knee osteoarthritis (KOA) are still unknown and it is hard to treat the disease fundamentally. With new therapeutic methods and techniques appearing, the present situation of treating the disease will be changed in the near future. Basic research of knee osteoarthritis will contribute to clarifying the pathogenesis and exploring the therapeutic methods. This article makes a brief review on the up-to-date basic researches of knee osteoarthritis by reviewing literature concerned in recent years.
authors.affiliation: Department of Rehabilitation, 3rd Affiliated Hospital of Zhejiang University of Traditional Chinese Medicine, Hangzhou 310005, Zhejiang, China.
authors.forename: Yun
authors.initials: Y
authors.lastname: Zhai
authors.forename: Gen-De
authors.initials: GD
authors.lastname: Gao
authors.forename: Shou-Yu
authors.initials: SY
authors.lastname: Xu
mesh_terms: D000818:Animals; D016207:Cytokines / Q000502:physiology; D004195:Disease Models, Animal; D015316:Genetic Therapy; D006801:Humans; D045726:Metalloproteases / Q000502:physiology; D020370:Osteoarthritis, Knee / Q000209:etiology* / Q000628:therapy*; D033581:Stem Cell Transplantation; D023822:Tissue Engineering
chemical_list: D016207:Cytokines; D045726:Metalloproteases