title: [Comorbidities in patients hospitalized due to chronic obstructive pulmonary disease. A comparative analysis of the ECCO and ESMI studies].
abstract: OBJECTIVE
  The presence of associated diseases is very frequent in patients hospitalized due to exacerbation of COPD. We have studied the comorbidities of patients admitted due to the disease in the Spanish Internal Medicine Services and we have evaluated the variations in regards to a previous study (ECCO study) performed two years earlier.
  
  
  METHODS
  A cross-sectional, multicenter and cohort study was performed. Patients hospitalized due to exacerbation of COPD in Spanish Internal Medicine Services were enrolled. All the patients were studied for the presence of comorbidity using the Charlson index and a questionnaire with relevant conditions not included in this index. Furthermore, spirometric data were collected on the duration of the disease or home treatment, among other variables.
  
  
  RESULTS
  A total of 1004 patients (398 in the ECCO study and 606 in the ESMI study) were studied. Of these, 89.4% were males, with mean age of 73 years (SD: 9.5 years). The patients of the ESMI study obtain higher scores on the Charlson index (3.04 vs. 2.71; P<0.01), and had a greater prevalence of ischemic heart disease (17 vs. 22.0%; P<0.05), heart failure (26.9 vs. 35.5%; P<.002), peripheral vascular disease (12.6 vs. 17.4%; P<.02), arterial hypertension (54.8 vs. 65.6%; P<.001), diabetes mellitus (29.4 vs. 37%; P<.02) and renal failure (6.5 vs. 16.8%; P<.0001).
  
  
  CONCLUSIONS
  This study confirms the elevated prevalence of associated diseases in patients with COPD who are admitted to the Spanish Internal Medicine Services and the increase of comorbidities.
authors.affiliation: Servicio de Medicina Interna, Hospital Universitario Mútua de Terrassa, Terrassa, Barcelona, España. palmagro@mutuaterrassa.es
authors.forename: P
authors.initials: P
authors.lastname: Almagro
authors.forename: F
authors.initials: F
authors.lastname: López
authors.forename: F J
authors.initials: FJ
authors.lastname: Cabrera
authors.forename: J
authors.initials: J
authors.lastname: Portillo
authors.forename: M
authors.initials: M
authors.lastname: Fernández-Ruiz
authors.forename: E
authors.initials: E
authors.lastname: Zubillaga
authors.forename: J
authors.initials: J
authors.lastname: Díez
authors.forename: P
authors.initials: P
authors.lastname: Román
authors.forename: J
authors.initials: J
authors.lastname: Murcia-Zaragoza
authors.forename: R
authors.initials: R
authors.lastname: Boixeda
authors.forename: C
authors.initials: C
authors.lastname: Murio
authors.forename: J B
authors.initials: JB
authors.lastname: Soriano
mesh_terms: D000368:Aged; D015331:Cohort Studies; D003430:Cross-Sectional Studies; D005260:Female; D006760:Hospitalization; D006801:Humans; D008297:Male; D029424:Pulmonary Disease, Chronic Obstructive / Q000150:complications*