title: An evaluation of the simultaneous use of the levonorgestrel-releasing intrauterine device (LNG-IUS, Mirena®) combined with endometrial ablation in the management of menorrhagia.
abstract: The objective of our study was to document the efficacy and possible complications in women who were treated for menorrhagia with the simultaneous use of endometrial ablation and the levonorgestrel-releasing intrauterine device. Women were offered this combined treatment if they complained of menorrhagia and needed contraception. A structured questionnaire was mailed to 150 women who had undergone this combined treatment; 105 (70%) returned a completed questionnaire. The mean duration of follow-up was 25 months (range 6-54 months). Following treatment, 53 women (50.5%) described their periods as being lighter than normal and 49 (46%) had become amenorrhoeic. Overall, 101 (96%) stated that they were satisfied with the treatment. Of the women, 95 (90.5%) said that the treatment had been a 'complete success'; eight (7.6%) 'partly successful' and two women (1.9%) said the treatment had been a 'failure'. One woman subsequently required a hysterectomy. This observational study supports the hypothesis that combined endometrial ablation and insertion of a levonorgestrel-releasing intrauterine device is an effective treatment for menorrhagia and has some advantages when compared with the individual use of these treatments.
authors.affiliation: Department of Gynaecology, Beaumont Hospital, Dublin, Ireland.
authors.forename: D
authors.initials: D
authors.lastname: Vaughan
authors.forename: P
authors.initials: P
authors.lastname: Byrne
mesh_terms: D000328:Adult; D003131:Combined Modality Therapy; D055356:Endometrial Ablation Techniques / Q000009:adverse effects / Q000379:methods*; D005260:Female; D006801:Humans; D007434:Intrauterine Devices / Q000009:adverse effects; D016912:Levonorgestrel / Q000009:adverse effects / Q000627:therapeutic use*; D008595:Menorrhagia / Q000188:drug therapy* / Q000601:surgery*; D017060:Patient Satisfaction; D011795:Surveys and Questionnaires; D016896:Treatment Outcome
chemical_list: D016912:Levonorgestrel