title: Immediate breast reconstruction with prostheses after conservative treatment plus intraoperative radiotherapy. long term esthetic and oncological outcomes.
abstract: Electron intraoperative radiotherapy (ELIOT) has been introduced for breast conservative treatment (BCT) with promising oncological outcome. Thus, immediate breast reconstruction with prosthesis after BCT became possible due to minimal radiation effect on local tissue from ELIOT. We reported oncological and esthetical results of 29 BCT patients who had immediate implant reconstruction plus 21 Gy-ELIOT as the sole radiation treatment. All patients had prosthesis in ipsilateral breast and had simultaneous contralateral augmentation for symmetrical procedure. The average age was 52.3 years. There were stage Ia thirteen cases, stage Ib seven cases, stage IIa six cases and stage IIIb one case and two cases of intraepithelial neoplasia. From 54.2 (36-88) months follow up, the capsular contracture grading in the reconstructed breast from ELIOT-side is comparable with non-irradiated contralateral side. There was one patient who developed local recurrence (LR) and later on dead with breast related event (LR=0.76% per year). There was no primary ipsilateral carcinomas and distant metastasis.
authors.affiliation: Department of Plastic and Reconstructive Surgery, European Institute of Oncology (EIO), Via Ripamonti, 435, 20141 Milan, Italy. francesca.delorenzi@ieo.it
authors.forename: Francesca
authors.initials: F
authors.lastname: De Lorenzi
authors.forename: Visnu
authors.initials: V
authors.lastname: Lohsiriwat
authors.forename: Benedetta
authors.initials: B
authors.lastname: Barbieri
authors.forename: Suanly
authors.initials: S
authors.lastname: Rodriguez Perez
authors.forename: Cristina
authors.initials: C
authors.lastname: Garusi
authors.forename: Jean Yves
authors.initials: JY
authors.lastname: Petit
authors.forename: Viviana
authors.initials: V
authors.lastname: Galimberti
authors.forename: Mario
authors.initials: M
authors.lastname: Rietjens
mesh_terms: D000328:Adult; D000368:Aged; D019928:Breast Implantation / Q000706:statistics & numerical data*; D001943:Breast Neoplasms / Q000453:epidemiology / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery*; D003131:Combined Modality Therapy; D004583:Electrons / Q000627:therapeutic use*; D004954:Esthetics; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007430:Intraoperative Care / Q000706:statistics & numerical data*; D007432:Intraoperative Period; D008408:Mastectomy / Q000706:statistics & numerical data; D008875:Middle Aged; D017060:Patient Satisfaction; D011880:Radiotherapy Planning, Computer-Assisted / Q000706:statistics & numerical data*; D018714:Radiotherapy, Adjuvant; D016896:Treatment Outcome; D016387:Women's Health