title: [A case of lung metastases of carcinoma of the ampulla of vater effectively treated with S-1].
abstract: A 70-year-old female patient underwent pylorus-preserving pancreaticoduodenectomy for carcinoma of the ampulla of Vater in March 2007. In April 2009, multiple lung metastases were detected by CT scanning. The patient was treated with S-1 (80mg/day, day 1-28, followed by 2-weeks withdrawal)from April 2009. The shrinkage of lung metastases was diagnosed as a complete response based on the Response Evaluation Criteria in Solid Tumors(RECIST). No severe toxicities were observed. S-1 is an effective and safe anti-cancer agent available for lung metastases of carcinoma of the ampulla of Vater.
authors.affiliation: Dept. of Gastroenterological Surgery and Oncology,Tazuke Kofukai Medical Institute, Kitano Hospital.
authors.forename: Hiroki
authors.initials: H
authors.lastname: Hashida
authors.forename: Yoshikage
authors.initials: Y
authors.lastname: Inoue
authors.forename: Kengo
authors.initials: K
authors.lastname: Hattori
authors.forename: Kentaro
authors.initials: K
authors.lastname: Kadono
authors.forename: Mio
authors.initials: M
authors.lastname: Yoshimura
authors.forename: Masahiro
authors.initials: M
authors.lastname: Yoshida
authors.forename: Satsuki
authors.initials: S
authors.lastname: Abe
authors.forename: Mafumi
authors.initials: M
authors.lastname: Miyake
authors.forename: Mami
authors.initials: M
authors.lastname: Yoshitomi
authors.forename: Akinari
authors.initials: A
authors.lastname: Nomura
authors.forename: Shugo
authors.initials: S
authors.lastname: Ueda
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Terajima
authors.forename: Nobuhiro
authors.initials: N
authors.lastname: Osaki
mesh_terms: D000368:Aged; D014670:Ampulla of Vater; D000964:Antimetabolites, Antineoplastic / Q000627:therapeutic use*; D003138:Common Bile Duct Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D004338:Drug Combinations; D004379:Duodenal Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy* / Q000556:secondary; D010094:Oxonic Acid / Q000627:therapeutic use*; D010190:Pancreatic Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D005641:Tegafur / Q000627:therapeutic use*; D014057:Tomography, X-Ray Computed
chemical_list: D000964:Antimetabolites, Antineoplastic; D004338:Drug Combinations; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid