title: Copper-catalyzed formation of C-O bonds by direct α-C-H bond activation of ethers using stoichiometric amounts of peroxide in batch and continuous-flow formats.
abstract: Peroxides and ethers in flow: 2-Carbonyl-substituted phenols and β-ketoesters react safely with ethers in a microreactor environment using a copper catalyst and an organic peroxide (TBHP). This protocol results in unsymmetrical acetal scaffolds not easily available otherwise (see scheme).
authors.affiliation: Inorganic and Physical Chemistry Division, Indian Institute of Chemical Technology, Tarnaka, Hyderabad-500 607, India.
authors.forename: G Sathish
authors.initials: GS
authors.lastname: Kumar
authors.forename: Bartholomäus
authors.initials: B
authors.lastname: Pieber
authors.forename: K Rajender
authors.initials: KR
authors.lastname: Reddy
authors.forename: C Oliver
authors.initials: CO
authors.lastname: Kappe