title: RFMapp: ribosome flow model application.
abstract: The RFMapp is a graphical user interface application based on the RFM (ribosome flow model), enabling the estimation of the translation elongation rates of messenger ribonucleic acids (mRNAs) and the profile of ribosomal densities along the mRNAs, in a computationally efficient way. The RFMapp is based on the approach previously described by Reuveni et al., and unlike other traditional approaches in the field, which are mainly related to the genes' mean codon translation efficiency, the RFM additionally considers the codon order, the ribosomes' size and their order. Thus, it has been shown that RFM outperforms traditional predictors when analyzing both heterologous and endogenous genes.
  
  
  METHODS
  Distributable cross-platform application and guideline are available for download at: http://www.cs.tau.ac.il/~tamirtul/RFM_Installers/install.htm.
authors.affiliation: The Blavatnik School of Computer Science, Faculty of Exact Sciences, Tel Aviv University, Ramat Aviv 69978, Israel.
authors.forename: Hadas
authors.initials: H
authors.lastname: Zur
authors.forename: Tamir
authors.initials: T
authors.lastname: Tuller
mesh_terms: D001483:Base Sequence; D003062:Codon / Q000235:genetics*; D019295:Computational Biology / Q000379:methods; D003196:Computer Graphics; D008958:Models, Molecular; D014176:Protein Biosynthesis; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism*; D012270:Ribosomes / Q000235:genetics / Q000378:metabolism*; D012441:Saccharomyces cerevisiae / Q000235:genetics; D012984:Software; D014584:User-Computer Interface
chemical_list: D003062:Codon; D012333:RNA, Messenger