title: A review of adenoid cystic carcinoma of the breast with emphasis on its molecular and genetic characteristics.
abstract: Breast carcinomas that do not express estrogen receptor α, progesterone receptor, or human epidermal growth factor receptor 2 are frequently grouped together as "triple negative" and considered an aggressive type of breast malignancy; however, this group is not homogeneous. Adenoid cystic carcinoma of the breast is a rare type of breast cancer with such triple-negative features and, generally, a more favorable clinical course. This comprehensive review describes diagnostic, molecular, and clinical features of adenoid cystic carcinoma and compares them with those of triple-negative breast carcinomas of no special type.
authors.affiliation: Department of Pathology, Clinical Center of the University of Sarajevo, Sarajevo, Bosnia-Herzegovina 71000.
authors.forename: Semir
authors.initials: S
authors.lastname: Vranic
authors.forename: Richard
authors.initials: R
authors.lastname: Bender
authors.forename: Juan
authors.initials: J
authors.lastname: Palazzo
authors.forename: Zoran
authors.initials: Z
authors.lastname: Gatalica
mesh_terms: D014408:Biomarkers, Tumor / Q000235:genetics / Q000378:metabolism*; D001943:Breast Neoplasms / Q000235:genetics / Q000378:metabolism* / Q000473:pathology; D003528:Carcinoma, Adenoid Cystic / Q000235:genetics / Q000378:metabolism* / Q000473:pathology; D066246:ErbB Receptors / Q000378:metabolism; D047628:Estrogen Receptor alpha / Q000378:metabolism; D005260:Female; D015972:Gene Expression Regulation, Neoplastic; D006801:Humans; D007150:Immunohistochemistry; D011980:Receptors, Progesterone / Q000378:metabolism
chemical_list: D014408:Biomarkers, Tumor; C506487:ESR1 protein, human; D047628:Estrogen Receptor alpha; D011980:Receptors, Progesterone; D066246:ErbB Receptors