title: Beamline AR-NW12A: high-throughput beamline for macromolecular crystallography at the Photon Factory.
abstract: AR-NW12A is an in-vacuum undulator beamline optimized for high-throughput macromolecular crystallography experiments as one of the five macromolecular crystallography (MX) beamlines at the Photon Factory. This report provides details of the beamline design, covering its optical specifications, hardware set-up, control software, and the latest developments for MX experiments. The experimental environment presents state-of-the-art instrumentation for high-throughput projects with a high-precision goniometer with an adaptable goniometer head, and a UV-light sample visualization system. Combined with an efficient automounting robot modified from the SSRL SAM system, a remote control system enables fully automated and remote-access X-ray diffraction experiments.
authors.affiliation: Structural Biology Research Center, Photon Factory, High Energy Research Organization, 1-1 Oho, Tsukuba, Ibaraki 305-0801, Japan. leonard.chavas@kek.jp
authors.forename: L M G
authors.initials: LM
authors.lastname: Chavas
authors.forename: N
authors.initials: N
authors.lastname: Matsugaki
authors.forename: Y
authors.initials: Y
authors.lastname: Yamada
authors.forename: M
authors.initials: M
authors.lastname: Hiraki
authors.forename: N
authors.initials: N
authors.lastname: Igarashi
authors.forename: M
authors.initials: M
authors.lastname: Suzuki
authors.forename: S
authors.initials: S
authors.lastname: Wakatsuki
mesh_terms: D000429:Alcohol Oxidoreductases; D057205:Automation, Laboratory; D018360:Crystallography, X-Ray / Q000379:methods*; D007243:Infectious bursal disease virus / Q000737:chemistry*; D046911:Macromolecular Substances / Q000737:chemistry; D009281:Naphthalenes / Q000737:chemistry; D011312:Pressure; D012984:Software; D013449:Sulfonamides / Q000737:chemistry; D017356:Synchrotrons / Q000295:instrumentation*; D014764:Viral Proteins / Q000737:chemistry; D014961:X-Ray Diffraction
chemical_list: D046911:Macromolecular Substances; D009281:Naphthalenes; D013449:Sulfonamides; D014764:Viral Proteins; C540973:pyrabactin; D000429:Alcohol Oxidoreductases