title: Selective inhibition of USP7.
abstract: The deubiquitinating enzyme USP7 is an emerging oncology and antiviral target. Reverdy et al., in this issue of Chemistry & Biology, disclose the first small-molecule inhibitor selective for USP7, which recapitulates its knockdown in cancer cells and hence demonstrates the therapeutic feasibility of USP7 inhibitors.
authors.affiliation: Biotechnology Research Institute, National Research Council Canada, 6100 Royalmount Avenue, Montreal, QC, H4P 2R2, Canada. robert.menard@cnrc-nrc.gc.ca
authors.forename: Robert
authors.initials: R
authors.lastname: Menard
authors.forename: Traian
authors.initials: T
authors.lastname: Sulea