title: Effect of virtual reality on cognition in stroke patients.
abstract: OBJECTIVE
  To investigate the effect of virtual reality on the recovery of cognitive impairment in stroke patients.
  
  
  METHODS
  Twenty-eight patients (11 males and 17 females, mean age 64.2) with cognitive impairment following stroke were recruited for this study. All patients were randomly assigned to one of two groups, the virtual reality (VR) group (n=15) or the control group (n=13). The VR group received both virtual reality training and computer-based cognitive rehabilitation, whereas the control group received only computer-based cognitive rehabilitation. To measure, activity of daily living cognitive and motor functions, the following assessment tools were used: computerized neuropsychological test and the Tower of London (TOL) test for cognitive function assessment, Korean-Modified Barthel index (K-MBI) for functional status evaluation, and the motricity index (MI) for motor function assessment. All recruited patients underwent these evaluations before rehabilitation and four weeks after rehabilitation.
  
  
  RESULTS
  The VR group showed significant improvement in the K-MMSE, visual and auditory continuous performance tests (CPT), forward digit span test (DST), forward and backward visual span tests (VST), visual and verbal learning tests, TOL, K-MBI, and MI scores, while the control group showed significant improvement in the K-MMSE, forward DST, visual and verbal learning tests, trail-making test-type A, TOL, K-MBI, and MI scores after rehabilitation. The changes in the visual CPT and backward VST in the VR group after rehabilitation were significantly higher than those in the control group.
  
  
  CONCLUSIONS
  Our findings suggest that virtual reality training combined with computer-based cognitive rehabilitation may be of additional benefit for treating cognitive impairment in stroke patients.
authors.affiliation: Department of Rehabilitation Medicine, Jeju National University College of Medicine, Jeju 690-767, Korea.
authors.forename: Bo Ryun
authors.initials: BR
authors.lastname: Kim
authors.forename: Min Ho
authors.initials: MH
authors.lastname: Chun
authors.forename: Lee Suk
authors.initials: LS
authors.lastname: Kim
authors.forename: Ji Young
authors.initials: JY
authors.lastname: Park