title: Clinical observation of fetal olfactory ensheathing glia transplantation (OEGT) in patients with complete chronic spinal cord injury.
abstract: This study was designed to observe the functional changes after fetal olfactory ensheathing glia transplantation (OEGT) into the spinal cord of patients with chronic spinal cord injury (SCI). Patients whose recovery had plateaued for longer than 6 months were enrolled. Six thoracic  patients were tested for safety and five cervical patients for efficacy. OEGT was performed according to the method developed by Huang. Average follow-up was 14 months (range 1.0-1.5 years). Sensation improved moderately (light touch 14.2, pin prick 13.6); as did spasticity (1-2  modified Ashworth scale down). Locomotion recovery was minimal (1.6). Useful reticular formation functions were observed, but due to a lack of appropriate outcome measure, they were not recorded and reported.
authors.affiliation: Department of Orthopedics, The Beijing Army General Hospital, 5 Nanmengcang Lane, Beijing, P.R. China.
authors.forename: Jun
authors.initials: J
authors.lastname: Wu
authors.forename: Tiansheng
authors.initials: T
authors.lastname: Sun
authors.forename: Chaoqun
authors.initials: C
authors.lastname: Ye
authors.forename: Jianhua
authors.initials: J
authors.lastname: Yao
authors.forename: Bing
authors.initials: B
authors.lastname: Zhu
authors.forename: Hongying
authors.initials: H
authors.lastname: He
mesh_terms: D000328:Adult; D017690:Cell Transplantation / Q000379:methods*; D002908:Chronic Disease; D005260:Female; D016332:Fetal Tissue Transplantation / Q000379:methods*; D005333:Fetus / Q000166:cytology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009457:Neuroglia / Q000637:transplantation*; D009830:Olfactory Bulb / Q000166:cytology* / Q000196:embryology; D013119:Spinal Cord Injuries / Q000534:rehabilitation / Q000601:surgery*