title: Cooperative modulation of mineral growth by prismatic-associated Asprich Sequences and Mg(II).
abstract: Cooperative effects of magnesium ions and acidic polypeptides originating from a family of proteins known as Asprich (mollusk Atrina rigida) were studied. In our previous studies, these two acidic polypeptides were found to be effective in controlling the morphology of the calcium carbonate mineral, the main inorganic constituent of prismatic layer of the mollusk shell. Since these Asprich sequences are believed to contain a putative magnesium binding domain, the morphology-controlling effects were further investigated with the addition of magnesium ions. The mineral morphology was dramatically changed by the combined influence of each polypeptides and the magnesium ions, substantiating the recognized importance of magnesium in the formation of calcium carbonate-based biominerals.
authors.affiliation: Department of Chemical Engineering, Soongsil University, Seoul 156-743, South Korea.
authors.forename: Il Won
authors.identifier: 0000-0001-8507-5279
authors.initials: IW
authors.lastname: Kim
authors.affiliation: Laboratory for Chemical Physics, New York University, New York, NY 10010, USA.
authors.forename: Sebastiano
authors.initials: S
authors.lastname: Collino
authors.affiliation: Laboratory for Chemical Physics, New York University, New York, NY 10010, USA.
authors.forename: John Spencer
authors.identifier: 0000-0002-9565-7296
authors.initials: JS
authors.lastname: Evans
mesh_terms: D060105:Animal Shells / Q000737:chemistry / Q000254:growth & development* / Q000378:metabolism; D000818:Animals; D002113:Calcification, Physiologic / Q000502:physiology*; D002119:Calcium Carbonate / Q000737:chemistry* / Q000378:metabolism; D008274:Magnesium / Q000737:chemistry* / Q000378:metabolism; D008903:Minerals; D008974:Mollusca / Q000378:metabolism*; D011506:Proteins / Q000378:metabolism
chemical_list: D008903:Minerals; D011506:Proteins; D002119:Calcium Carbonate; D008274:Magnesium