title: Epidemiology of end-stage renal disease and hemodialysis treatment in Serbia at the turn of the millennium.
abstract: The study presents the epidemiological features of patients treated with renal replacement therapy (RRT) in Serbia from 1997 to 2009 and compares the results of hemodialysis treatment in 1999 and 2009. Epidemiological data were obtained from the National Registry of RRT patients and data on hemodialysis treatment from special surveys conducted in 1999 and 2009. Within the period 1997-2009 the incidence of patients on RRT increased from 108 to 179 per million population (pmp), prevalence rose from 435 to 699 pmp, while mortality rate fell from 20.7% to 16.7%. The frequency of patients with glomerulonephritis decreased, while that of patients with diabetes and hypertensive nephropathy increased. In late 2009 there were 5208 patients receiving RRT in Serbia. Within the examined period new hemodialysis and reverse osmosis equipment were purchased, high-flux dialyzers with synthetic membranes were increasingly used and the number of patients receiving hemodiafiltration increased to 17.6%. Kt/V greater than 1.2 was recorded in 16% of the patients in 1999 but 52% in 2009. Options for correction of anemia and mineral disorders have also improved. The percentage of patients with HbsAg (13.8% vs. 4.8%) as well as anti-hepatitis C virus antibodies positive patients (23.2% vs. 12.7%) was significantly lower in 2009 than in 1999. Both the incidence and prevalence of RRT patients in Serbia are rising continuously, while the mortality rate is falling. More favorable conditions for dialysis treatment have brought about significant improvement in the results over the last 10 years.
authors.affiliation: Academy of Medical Science, SMS, Serbia. ljubicadjukanovic@yahoo.com
authors.forename: Ljubica
authors.initials: L
authors.lastname: Djukanović
authors.forename: Biserka
authors.initials: B
authors.lastname: Aksić-Miličević
authors.forename: Miodrag
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authors.lastname: Antić
authors.forename: Jovan
authors.initials: J
authors.lastname: Baković
authors.forename: Željko
authors.initials: Ž
authors.lastname: Varga
authors.forename: Biljana
authors.initials: B
authors.lastname: Gojaković
authors.forename: Nada
authors.initials: N
authors.lastname: Dimković
authors.forename: Verica
authors.initials: V
authors.lastname: Đorđević
authors.forename: Vidojko
authors.initials: V
authors.lastname: Đorđević
authors.forename: Stevan
authors.initials: S
authors.lastname: Đurić
authors.forename: Sunčica
authors.initials: S
authors.lastname: Đurić
authors.forename: Nenad
authors.initials: N
authors.lastname: Zec
authors.forename: Rosa
authors.initials: R
authors.lastname: Jelačić
authors.forename: Zoran
authors.initials: Z
authors.lastname: Kovačević
authors.forename: Tatjana
authors.initials: T
authors.lastname: Lazarević
authors.forename: Višnja
authors.initials: V
authors.lastname: Ležaić
authors.forename: Milan
authors.initials: M
authors.lastname: Mandić
authors.forename: Ivko
authors.initials: I
authors.lastname: Marić
authors.forename: Srboljub
authors.initials: S
authors.lastname: Milenković
authors.forename: Olivera
authors.initials: O
authors.lastname: Milićević
authors.forename: Milena
authors.initials: M
authors.lastname: Mišković
authors.forename: Igor
authors.initials: I
authors.lastname: Mitić
authors.forename: Zora
authors.initials: Z
authors.lastname: Nikolić
authors.forename: Draga
authors.initials: D
authors.lastname: Pilipović
authors.forename: Stevo
authors.initials: S
authors.lastname: Plješa
authors.forename: Miroslava
authors.initials: M
authors.lastname: Radaković
authors.forename: Nenad
authors.initials: N
authors.lastname: Rakić
authors.forename: Vanja
authors.initials: V
authors.lastname: Rangelov
authors.forename: Radivoje
authors.initials: R
authors.lastname: Stojanović
authors.forename: Marina
authors.initials: M
authors.lastname: Stojanović-Stanojević
authors.forename: Biserka
authors.initials: B
authors.lastname: Tirmenštajn-Janković
authors.forename: Branimir
authors.initials: B
authors.lastname: Haviža-Lilić
authors.forename: Edvin
authors.initials: E
authors.lastname: Hadžibulić
authors.forename: Rajko
authors.initials: R
authors.lastname: Hrvačević
authors.forename: Anica
authors.initials: A
authors.lastname: Cvetičanin
mesh_terms: D005260:Female; D006801:Humans; D015994:Incidence; D007676:Kidney Failure, Chronic / Q000453:epidemiology* / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D006435:Renal Dialysis / Q000379:methods* / Q000706:statistics & numerical data*; D055771:Serbia / Q000453:epidemiology