title: Extensively heated milk and egg as oral immunotherapy.
abstract: OBJECTIVE
  The introduction of extensively heated milk and egg protein into the diet has been explored in recent years.
  
  
  RESULTS
  Studies have suggested that a large subset of children who react to unheated milk or egg can tolerate extensively heated forms of these foods. Immunologic changes induced by a diet containing baked milk and egg are similar to changes that have been observed during oral immunotherapy trials. The baked milk and egg diet appears to accelerate the development of regular milk and egg tolerance when compared with strict avoidance.
  
  
  CONCLUSIONS
  An oral challenge to extensively heated milk and egg into milk and egg allergic children's diets should be considered when appropriate. Oral food challenges are the most reliable means of establishing a diagnosis and should be undertaken under physician supervision.
authors.affiliation: Jaffe Food Allergy Institute, Division of Allergy and Immunology, Department of Pediatrics, Mount Sinai Medical School, New York, New York, USA.
authors.forename: Faith
authors.initials: F
authors.lastname: Huang
authors.forename: Anna
authors.initials: A
authors.lastname: Nowak-Węgrzyn
mesh_terms: D000284:Administration, Oral; D000818:Animals; D002648:Child; D002986:Clinical Trials as Topic; D003888:Desensitization, Immunologic / Q000379:methods*; D021181:Egg Hypersensitivity / Q000276:immunology / Q000628:therapy*; D004531:Eggs; D006358:Hot Temperature; D006801:Humans; D007108:Immune Tolerance; D008892:Milk / Q000276:immunology*; D016269:Milk Hypersensitivity / Q000276:immunology / Q000628:therapy*; D016896:Treatment Outcome