title: Regional intravenous gentamicin administration for treatment of postoperative tarso-metatarsal infection in a dog--a case report.
abstract: The regional intravenous antibiotic administration has been used to achieve high local concentrations of antibiotics into the extremities. The goal of this case report was to describe a known, but not often used technique of local administration of antibiotics for treatment of acute soft tissue, joint or bone infection in a dog, which suffered from chronic renal failure. In a seven years old Great Dane tarso-metatarsal arthrodesis was performed and three days after surgery infection was obvious. Gentamicin-sensitive E. co i was found by antibiogram. A tourniquet was tightened on the affected limb and gentamicin was administered in a dosage of 0,5 mg/kg every twelve hours via an intravenous catheter placed in the saphenous vein. The therapy lasted for ten days and wound healing was progressive. Regional intravenous gentamicin administration was very effective in treating distal extremity infection.
authors.affiliation: Clinic for Surgery, Orthopedics and Ophthalmology, Faculty of Veterinary Medicine, University of Zagreb, Zagreb, Croatia. dvnuk@vef.hr
authors.forename: Drazen
authors.initials: D
authors.lastname: Vnuk
authors.forename: Marko
authors.initials: M
authors.lastname: Stejskal
authors.forename: Andrija
authors.initials: A
authors.lastname: Musulin
authors.forename: Drazen
authors.initials: D
authors.lastname: Maticić
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D001174:Arthrodesis / Q000009:adverse effects / Q000662:veterinary; D002408:Catheters, Indwelling / Q000662:veterinary; D004283:Dog Diseases / Q000188:drug therapy*; D004285:Dogs; D004926:Escherichia coli / Q000187:drug effects; D004927:Escherichia coli Infections / Q000188:drug therapy / Q000209:etiology / Q000662:veterinary*; D005260:Female; D005839:Gentamicins / Q000008:administration & dosage*; D007262:Infusions, Intravenous / Q000379:methods / Q000662:veterinary; D004204:Joint Dislocations / Q000601:surgery / Q000662:veterinary*; D008684:Metatarsus / Q000601:surgery; D011183:Postoperative Complications / Q000188:drug therapy / Q000662:veterinary*; D012501:Saphenous Vein; D013640:Tarsal Joints / Q000601:surgery
chemical_list: D000900:Anti-Bacterial Agents; D005839:Gentamicins