title: GeneclusterViz: a tool for conserved gene cluster visualization, exploration and analysis.
abstract: BACKGROUND
  Gene clusters are arrangements of functionally related genes on a chromosome. In bacteria, it is expected that evolutionary pressures would conserve these arrangements due to the functional advantages they provide. Visualization of conserved gene clusters across multiple genomes provides key insights into their evolutionary histories. Therefore, a software tool that enables visualization and functional analyses of gene clusters would be a great asset to the biological research community.
  
  
  RESULTS
  We have developed GeneclusterViz, a Java-based tool that allows for the visualization, exploration and downstream analyses of conserved gene clusters across multiple genomes. GeneclusterViz combines an easy-to-use exploration interface for gene clusters with a host of other analysis features such as multiple sequence alignments, phylogenetic analyses and integration with the KEGG pathway database.
  
  
  BACKGROUND
  http://biohealth.snu.ac.kr/GeneclusterViz/; http://microbial.informatics.indiana.edu/GeneclusterViz/
authors.affiliation: School of Informatics and Computing, Indiana University Bloomington, IN 47404, USA.
authors.forename: Vikas R
authors.initials: VR
authors.lastname: Pejaver
authors.forename: Jaehyun
authors.initials: J
authors.lastname: An
authors.forename: Sungmin
authors.initials: S
authors.lastname: Rhee
authors.forename: Ankita
authors.initials: A
authors.lastname: Bhan
authors.forename: Jeong-Hyeon
authors.initials: JH
authors.lastname: Choi
authors.forename: Boshu
authors.initials: B
authors.lastname: Liu
authors.forename: Heewook
authors.initials: H
authors.lastname: Lee
authors.forename: Pamela J
authors.initials: PJ
authors.lastname: Brown
authors.forename: David
authors.initials: D
authors.lastname: Kysela
authors.forename: Yves V
authors.initials: YV
authors.lastname: Brun
authors.forename: Sun
authors.initials: S
authors.lastname: Kim
mesh_terms: D020561:Alphaproteobacteria / Q000145:classification* / Q000235:genetics*; D016000:Cluster Analysis; D004926:Escherichia coli / Q000235:genetics; D016678:Genome; D005810:Multigene Family; D010802:Phylogeny; D016415:Sequence Alignment; D012984:Software