title: Virus capture using anionic polymer-coated magnetic beads (review).
abstract: The recent incidence of emerging and re-emerging viruses is a serious health             concern worldwide. The development of transportation systems, such as air travel,             has increased the risk of a global pandemic caused by emerging viruses. Agents             causing novel infections are often zoonotic, crossing from the natural host into             the human population. Hence, comprehensive surveillance of virus-infected animals             as well as humans is required. However, the number of virus particles in clinical             and environmental samples is usually very low. Thus, a method to concentrate the             virus is sometimes required in order to enable detection. We recently reported             that magnetic beads coated with an anionic polymer, poly(methyl vinyl ether-maleic             anhydride) can be used to facilitate the rapid and sensitive detection of viruses.             In this review, we describe recent developments for concentrating viruses using             anionic magnetic beads.
authors.affiliation: Laboratory of Biometabolic Chemistry, School of Health Sciences, Faculty of Medicine, University of the Ryukyus, Nishihara, Okinawa 903-0215, Japan. sakudo@med.u-ryukyu.ac.jp
authors.forename: Akikazu
authors.initials: A
authors.lastname: Sakudo
authors.forename: Takashi
authors.initials: T
authors.lastname: Onodera
mesh_terms: D006801:Humans; D060328:Magnetic Phenomena; D058185:Magnetite Nanoparticles / Q000821:virology*; D008863:Microspheres; D011091:Polyesters; D011108:Polymers; D014780:Viruses / Q000737:chemistry / Q000302:isolation & purification*
chemical_list: D058185:Magnetite Nanoparticles; D011091:Polyesters; D011108:Polymers