title: "Accelerated ear-age": a new measure of chemotherapy-induced ototoxicity.
abstract: Currently, there are several different scales that grade chemotherapy-induced ototoxicity. This report highlights how the implications of the conclusions drawn from each scale differ and compare these prior scales to a more functionally based scale developed at Children's Hospital Boston. Additionally, this report introduces the concept of "ear-age," akin to the age at which one would expect the observed decrease in hearing as a consequence of normative aging (but documented in a child or young adult following chemotherapy).
authors.affiliation: Department of Otolaryngology and Communication Enhancement, Children's Hospital Boston, Boston, Massachusetts, USA. brian.fligor@childrens.harvard.edu
authors.forename: Brian J
authors.initials: BJ
authors.lastname: Fligor
authors.forename: Jennie D
authors.initials: JD
authors.lastname: Krasker
authors.forename: Doojduen
authors.initials: D
authors.lastname: Villaluna
authors.forename: Mark
authors.initials: M
authors.lastname: Krailo
authors.forename: A Lindsay
authors.initials: AL
authors.lastname: Frazier
mesh_terms: D000293:Adolescent; D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000009:adverse effects*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006316:Hearing Loss, High-Frequency / Q000139:chemically induced* / Q000503:physiopathology*; D006801:Humans; D008297:Male; D009373:Neoplasms, Germ Cell and Embryonal / Q000188:drug therapy*