title: Treatment for restless legs syndrome secondary to chronic liver disease: a case report.
abstract: We report a patient with restless legs syndrome (RLS) and chronic liver disease (CLD), whose RLS symptoms fluctuated in correlation with serum ammonia level. RLS in this patient seemed to be secondary to CLD because palliative medications for the liver dysfunction showed an additional effect on RLS symptoms that were partially controlled by levodopa. CLD should be born in mind as one of the factors to cause RLS symptoms; the therapeutic mechanism of RLS enhanced by palliative medications for CLD is discussed.
authors.affiliation: Center for Sleep-related Disorders, Kansai Electric Power Hospital, Japan. toguri@mac.com
authors.forename: Takuya
authors.initials: T
authors.lastname: Oguri
authors.forename: Hanako
authors.initials: H
authors.lastname: Sugiyama
authors.forename: Toshiaki
authors.initials: T
authors.lastname: Hamano
authors.forename: Naoko
authors.initials: N
authors.lastname: Tachibana
mesh_terms: D000368:Aged; D000597:Amino Acids, Branched-Chain / Q000627:therapeutic use; D002908:Chronic Disease; D006801:Humans; D007980:Levodopa / Q000627:therapeutic use; D008107:Liver Diseases / Q000150:complications* / Q000175:diagnosis / Q000628:therapy*; D008297:Male; D012148:Restless Legs Syndrome / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy*; D016896:Treatment Outcome
chemical_list: D000597:Amino Acids, Branched-Chain; D007980:Levodopa