title: Uncertainty in environmental health impact assessment: quantitative methods and perspectives.
abstract: Environmental health impact assessment models are subjected to great uncertainty due to the complex associations between environmental exposures and health. Quantifying the impact of uncertainty is important if the models are used to support health policy decisions. We conducted a systematic review to identify and appraise current methods used to quantify the uncertainty in environmental health impact assessment. In the 19 studies meeting the inclusion criteria, several methods were identified. These were grouped into random sampling methods, second-order probability methods, Bayesian methods, fuzzy sets, and deterministic sensitivity analysis methods. All 19 studies addressed the uncertainty in the parameter values but only 5 of the studies also addressed the uncertainty in the structure of the models. None of the articles reviewed considered conceptual sources of uncertainty associated with the framing assumptions or the conceptualisation of the model. Future research should attempt to broaden the way uncertainty is taken into account in environmental health impact assessments.
authors.affiliation: Department of Social and Environmental Health Research, London School of Hygiene and Tropical Medicine, London, UK. marco.mesa-frias@lshtm.ac.uk
authors.forename: Marco
authors.initials: M
authors.lastname: Mesa-Frias
authors.forename: Zaid
authors.initials: Z
authors.lastname: Chalabi
authors.forename: Tazio
authors.initials: T
authors.lastname: Vanni
authors.forename: Anna M
authors.initials: AM
authors.lastname: Foss
mesh_terms: D004781:Environmental Exposure; D004782:Environmental Health / Q000379:methods*; D062489:Health Impact Assessment / Q000379:methods*; D006801:Humans; D008962:Models, Theoretical; D035501:Uncertainty