title: [Non-Descemet stripping automated endothelial keratoplasty for graft failure after penetrating keratoplasty].
abstract: OBJECTIVE
  To report clinical results of non-Descemet stripping automated endothelial keratoplasty (nDSAEK) to treat graft failure after penetrating keratoplasty.
  
  
  METHODS
  It was a retrospective case series study. Five cases of grafts failure after penetrating keratoplasty (PKP) were enrolled in this study. All patients had a cloudy and swollen grafts, which thicker than 620 µm, and had foreign body sensation, vision decrease. Of this 5 cases, 4 of them are pseudophakic eye, 1 is aphakic eye. One patient had previous vitrectomy, and 3 of them had one time history of PKP, 2 of them had twice PKP treatment. All cases were treated by nDSAEK, the nDSAEK grafts were prepared as a 200 µm thickness and 8.00 to 8.75 mm in diameter by using hand or femtosecond laser assisted methods. The graft was inserted by forceps or suture pulling method through a 5.00 mm scleral tunel incision.
  
  
  RESULTS
  One graft dislocated at 1day postoperation, and was reattached by rebuble. All grafts keep clear during 8 - 28 months follow up period, and no immune rejection episodes were noted. The endothelial density were 865 to 2410/mm(2). Postoperative best corrected vision (pBCVA) are better or equal to previous BCVA after pkp.
  
  
  CONCLUSIONS
  nDSAEK appears a good alternative surgical method for patients of grafts failure after pkp, especially for high risk patients of immune rejection.
authors.affiliation: Shenyang Aier Eye Hospital, Aier Eye Hospitals Group, Shenyang 110003, China. shaoweili2005@vip.163.com
authors.forename: Shao-wei
authors.initials: SW
authors.lastname: Li
authors.forename: Tie-hong
authors.initials: TH
authors.lastname: Chen
authors.forename: Jian-hua
authors.initials: JH
authors.lastname: Ning
authors.forename: Fang-qi
authors.initials: FQ
authors.lastname: Lü
authors.forename: Zuo-feng
authors.initials: ZF
authors.lastname: Guo
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D057111:Descemet Stripping Endothelial Keratoplasty; D005260:Female; D006085:Graft Survival; D006801:Humans; D015948:Keratoplasty, Penetrating; D008297:Male; D008875:Middle Aged; D012086:Reoperation; D012189:Retrospective Studies; D017211:Treatment Failure; D016896:Treatment Outcome