title: Rhabdomyolysis.
abstract: Rhabdomyolysis is the destruction of a significant amount of striated muscle, leading to disruptions in fluid balance, electrolytes and renal function. It may have either traumatic (such as crush injury) or non-traumatic causes. Diagnosis is typically made through the timely determination of the serum creatine kinase activity in a patient with a suggestive history or clinical features. Treatment is supportive, with generous intravenous hydration and correction of electrolyte abnormalities. Sometimes haemofiltration or dialysis is required, but the renal prognosis is generally good.
authors.affiliation: Acute Medicine in the Intensive Care Unit, Homerton University Hospital, London E9 6SR. jfdwolff@doctors.org.uk
authors.forename: Jacob F
authors.initials: JF
authors.lastname: de Wolff
mesh_terms: D003444:Crush Syndrome / Q000150:complications; D003937:Diagnosis, Differential; D006801:Humans; D009135:Muscular Diseases / Q000150:complications; D012206:Rhabdomyolysis / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology* / Q000628:therapy*; D016482:Urinalysis