title: Spread of carbapenemase NDM-1 producers: the situation in India and what may be proposed.
abstract: New Delhi metallo-β-lactamase 1 (NDM-1) producers, first identified from patients hospitalized in India, are now reported worldwide. The Indian subcontinent is clearly a main reservoir of NDM-1 producers. In order to slow down the spread of these NDM-1-positive Enterobacteriaceae, first in India and then worldwide, a series of measures must be implemented as soon as possible. These include discouraging the over-the-counter sale of antibiotics, improving basic and extended knowledge on hygiene, and the wide-scale detection of bla(NDM-1), in both infecting agents and in the carrier state for at-risk patients.
authors.affiliation: Medical Microbiology and Molecular Biology Laboratory, Interdisciplinary Biotechnology Unit, A.M.U, Aligarh, India. asad.k@rediffmail.com
authors.forename: Asad U
authors.initials: AU
authors.lastname: Khan
authors.forename: Patrice
authors.initials: P
authors.lastname: Nordmann
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D015780:Carbapenems / Q000494:pharmacology*; D004363:Drug Utilization / Q000639:trends; D004755:Enterobacteriaceae / Q000201:enzymology* / Q000302:isolation & purification; D004756:Enterobacteriaceae Infections / Q000453:epidemiology* / Q000382:microbiology; D006801:Humans; D007194:India; D018440:beta-Lactam Resistance; D001618:beta-Lactamases / Q000235:genetics* / Q000378:metabolism*
chemical_list: D000900:Anti-Bacterial Agents; D015780:Carbapenems; D001618:beta-Lactamases; C552864:beta-lactamase NDM-1