title: Dehydrative C-H alkylation and alkenylation of phenols with alcohols: expedient synthesis for substituted phenols and benzofurans.
abstract: A well-defined cationic Ru-H complex catalyzes the dehydrative C-H alkylation reaction of phenols with alcohols to form ortho-substituted phenol products. Benzofuran derivatives are efficiently synthesized from the dehydrative C-H alkenylation and annulation reaction of phenols with 1,2-diols. The catalytic C-H coupling method employs cheaply available phenols and alcohols, exhibits a broad substrate scope, tolerates carbonyl and amine functional groups, and liberates water as the only byproduct.
authors.affiliation: Department of Chemistry, Marquette University, Milwaukee, Wisconsin 53201-1881, USA.
authors.forename: Dong-Hwan
authors.initials: DH
authors.lastname: Lee
authors.forename: Ki-Hyeok
authors.initials: KH
authors.lastname: Kwon
authors.forename: Chae S
authors.initials: CS
authors.lastname: Yi