title: A turn-on fluorescent probe based on hydroxylamine oxidation for detecting ferric ion selectively in living cells.
abstract: We have described a turn on fluorescent probe BOD-NHOH based on hydroxylamine oxidation for detecting intracellular ferric ions. The probe comprises a signal transducer of BODIPY dye and a Fe(3+)-response modulator of hydroxylamine. It is readily employed for assessing intracellular ferric ion levels, and confocal imaging is achieved successfully.
authors.affiliation: Key Laboratory of Coastal Zone Environmental Processes, Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences, Yantai 264003, PR China.
authors.forename: Rui
authors.initials: R
authors.lastname: Wang
authors.forename: Fabiao
authors.initials: F
authors.lastname: Yu
authors.forename: Ping
authors.initials: P
authors.lastname: Liu
authors.forename: Lingxin
authors.initials: L
authors.lastname: Chen
mesh_terms: D001896:Boron Compounds / Q000737:chemistry; D045744:Cell Line, Tumor; D005290:Ferric Compounds / Q000032:analysis*; D005456:Fluorescent Dyes / Q000737:chemistry*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D019811:Hydroxylamine / Q000737:chemistry*; D007477:Ions / Q000737:chemistry; D018613:Microscopy, Confocal; D010084:Oxidation-Reduction
chemical_list: C095489:4,4-difluoro-4-bora-3a,4a-diaza-s-indacene; D001896:Boron Compounds; D005290:Ferric Compounds; D005456:Fluorescent Dyes; D007477:Ions; D019811:Hydroxylamine