title: [Secondary gliosarcoma: case report].
abstract: Gliosarcoma is a rare tumor of the central nervous system, consisting of gliomatous and sarcomatous elements. The glioblastoma can undergo a change in phenotype, transforming into a gliosarcoma, especially when the tumor has been treated with radiotherapy. Features unique to gliosarcoma compared to glioblastoma include their potential to appear similar to a meningioma at macroscopy, repeated reports of metastases and infrequency of EGFR mutations. We present a case of secondary gliosarcoma to emphasize on the specificities, essentially diagnostical of this rare entity.
authors.affiliation: Service d'anatomie pathologique, hôpital militaire d'instruction Mohammed V de Rabat, Rabat, Maroc. rajae.tahri@gmail.com
authors.forename: Rajae
authors.initials: R
authors.lastname: Tahri
authors.forename: Omar
authors.initials: O
authors.lastname: Boulahroud
authors.forename: Khadija
authors.initials: K
authors.lastname: Setti
authors.forename: Mohamed
authors.initials: M
authors.lastname: Oukabli
authors.forename: Mohamed Réda
authors.initials: MR
authors.lastname: El Ochi
authors.forename: Ali
authors.initials: A
authors.lastname: Akhaddar
authors.forename: Mohammed
authors.initials: M
authors.lastname: Boucetta
authors.forename: Abderrahmane
authors.initials: A
authors.lastname: Albouzidi
mesh_terms: D001932:Brain Neoplasms / Q000175:diagnosis* / Q000628:therapy; D018316:Gliosarcoma / Q000175:diagnosis* / Q000628:therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D016609:Neoplasms, Second Primary / Q000473:pathology*