title: Iodine(III)-mediated intermolecular allylic amination under metal-free conditions.
abstract: A new approach to direct intermolecular allylic amination has been developed using metal-free conditions at room temperature. The reaction employs a hypervalent iodine(III) reagent as an oxidant and bistosylimide as a nitrogen source. A series of different allylic aminations are presented with up to a 99% yield. Mechanistic studies including isotope labeling and Hammett correlation suggest that depending on the substrate structure two different mechanisms can be operating.
authors.affiliation: Institute of Chemical Research of Catalonia (ICIQ), Av. Països Catalans 16, 43007 Tarragona, Spain.
authors.forename: José A
authors.initials: JA
authors.lastname: Souto
authors.forename: Debora
authors.initials: D
authors.lastname: Zian
authors.forename: Kilian
authors.initials: K
authors.lastname: Muñiz