title: Reliability and validity of the Cystic Fibrosis Questionnaire-Revised for children and parents in Turkey: cross-sectional study.
abstract: OBJECTIVE
  The purpose of study was to translate Cystic Fibrosis Questionnaire-Revised (CFQ-R) into Turkish for children with cystic fibrosis (CF) and evaluate its reliability and validity. This is the first CF-specific health-related quality of life (HRQOL) measure validated in a Muslim country.
  
  
  METHODS
  Fifty-one children aged 6-13 years treated at four centers in Turkey and 30 parents participated in this cross-sectional study. Demographic characteristics and disease severity parameters were recorded for all participants. All participants completed the parent or child versions of CFQ-R and KINDL questionnaires at enrollment. Reliability and construct validity analysis were carried out.
  
  
  RESULTS
  Both children and parents endorsed a range of responses, with no evidence of floor or ceiling effects. Item-to-total correlations indicated that most items were more highly correlated with their intended scale than competing scales. Good internal consistency was found for majority of child and parent scales. CFQ-R scales correlated significantly with clinical indices of disease severity. Good evidence of convergent validity with a generic HRQOL scale was found.
  
  
  CONCLUSIONS
  Turkish versions of CFQ-R Child and Parent instruments have demonstrated adequate reliability and validity and can be utilized in clinical trials or integrated into clinical evaluation and follow-up of Turkish children with CF.
authors.affiliation: Department of Pediatric Allergy and Pulmonology, Medical Faculty, Celal Bayar University, Manisa, Turkey. hyukselefe@hotmail.com
authors.forename: Hasan
authors.initials: H
authors.lastname: Yuksel
authors.forename: Ozge
authors.initials: O
authors.lastname: Yilmaz
authors.forename: Deniz
authors.initials: D
authors.lastname: Dogru
authors.forename: Bulent
authors.initials: B
authors.lastname: Karadag
authors.forename: Fatih
authors.initials: F
authors.lastname: Unal
authors.forename: Alexandra L
authors.initials: AL
authors.lastname: Quittner
mesh_terms: D000293:Adolescent; D002648:Child; D003430:Cross-Sectional Studies; D003550:Cystic Fibrosis / Q000523:psychology*; D005260:Female; D006304:Health Status; D006801:Humans; D007802:Language; D008297:Male; D010290:Parents / Q000523:psychology*; D011594:Psychometrics / Q000706:statistics & numerical data*; D011788:Quality of Life; D015203:Reproducibility of Results; D018434:Sickness Impact Profile; D012959:Socioeconomic Factors; D011795:Surveys and Questionnaires; D014175:Translating; D014421:Turkey