title: Cytotoxicity of selected medicinal and nonmedicinal plant extracts to microbial and cervical cancer cells.
abstract: This study investigated the cytotoxicity of 55 species of plants. Each plant was rated as medicinal, or nonmedicinal based on the existing literature. About 79% of the medicinal plants showed some cytotoxicity, while 75% of the nonmedicinal plants showed bioactivity. It appears that Asteraceae, Labiatae, Pinaceae, and Chenopodiaceae were particularly active against human cervical cancer cells. Based on the literature, only three of the 55 plants have been significantly investigated for cytotoxicity. It is clear that there is much toxicological work yet to be done with both medicinal and nonmedicinal plants.
authors.affiliation: Department of Plant and Wildlife Sciences, Brigham Young University, Provo, UT 84602, USA. gary_booth@byu.edu
authors.forename: Gary M
authors.initials: GM
authors.lastname: Booth
authors.forename: Robert D
authors.initials: RD
authors.lastname: Malmstrom
authors.forename: Erica
authors.initials: E
authors.lastname: Kipp
authors.forename: Alexandra
authors.initials: A
authors.lastname: Paul
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D000970:Antineoplastic Agents / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects*; D002470:Cell Survival / Q000187:drug effects*; D005260:Female; D006367:HeLa Cells; D006801:Humans; D008517:Phytotherapy; D010936:Plant Extracts / Q000494:pharmacology*; D010944:Plants / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D002583:Uterine Cervical Neoplasms
chemical_list: D000900:Anti-Bacterial Agents; D000970:Antineoplastic Agents; D010936:Plant Extracts