title: Solution behavior of normal and reverse triblock copolymers (pluronic L44 and 10R5) individually and in binary mixture.
abstract: Solution properties of pluronics L44 or L [(PEO)(10)(PPO)(23)(PEO)(10)] and 10R5 or R [(PPO)(8)(PEO)(22)(PPO)(8)] were studied individually as well in their binary mixtures in aqueous medium. The critical micelle concentration (CMC), critical micelle temperature, and cloud point (CP) were determined. Ideal and nonideal behaviors of their mixtures in the formation of CMC and CP were observed; the energetics of the studied processes were determined. Spectrophotometry, isothermal titration calorimetry and dynamic light scattering (DLS) methods were used for evaluations. Morphologies of the dispersed L, R, and their mixtures along with their polydispersities were determined from DLS measurements. Atomic force microscopy was also employed. The interfacial properties of L and R were investigated forming Langmuir monolayers in a surface balance. The surface pressures (π) generated by the compounds were moderate, the area per molecule was higher for R than L. R has shown antibacterial activity against both gram positive and gram negative bacteria whereas L was inactive in this respect.
authors.affiliation: Centre for Surface Science, Department of Chemistry, Jadavpur University, Kolkata 700032, India.
authors.forename: Bappaditya
authors.initials: B
authors.lastname: Naskar
authors.forename: Soumen
authors.initials: S
authors.lastname: Ghosh
authors.forename: Satya P
authors.initials: SP
authors.lastname: Moulik
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology; D045424:Complex Mixtures / Q000737:chemistry*; D004305:Dose-Response Relationship, Drug; D004926:Escherichia coli / Q000187:drug effects; D008823:Micelles; D008826:Microbial Sensitivity Tests; D020442:Poloxamer / Q000737:chemistry* / Q000494:pharmacology; D012996:Solutions; D013211:Staphylococcus aureus / Q000187:drug effects; D013696:Temperature
chemical_list: D000900:Anti-Bacterial Agents; D045424:Complex Mixtures; D008823:Micelles; D012996:Solutions; D020442:Poloxamer