title: Cerium oxide nanoparticles scavenge nitric oxide radical (˙NO).
abstract: In this study we have obtained evidence that cerium oxide nanoparticles (CeO(2) NPs) are able to scavenge nitric oxide radical. Surprisingly, this activity is present in CeO(2) NPs with a lower level of cerium in the 3+ state (CeO(2) NPs with low 3+/4+ ratio and therefore a reduced number of oxygen vacancies), in contrast to the superoxide scavenging properties which are correlated with an increased level of cerium in the 3+ state (CeO(2) NPs with high 3+/4+ ratio and therefore an increased number of oxygen vacancies).
authors.affiliation: Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, FL, USA.
authors.forename: Janet M
authors.initials: JM
authors.lastname: Dowding
authors.forename: Talib
authors.initials: T
authors.lastname: Dosani
authors.forename: Amit
authors.initials: A
authors.lastname: Kumar
authors.forename: Sudipta
authors.initials: S
authors.lastname: Seal
authors.forename: William T
authors.initials: WT
authors.lastname: Self
mesh_terms: D002563:Cerium / Q000737:chemistry*; D016166:Free Radical Scavengers / Q000737:chemistry*; D053768:Metal Nanoparticles / Q000737:chemistry*; D009569:Nitric Oxide / Q000737:chemistry*; D013056:Spectrophotometry, Ultraviolet
chemical_list: D016166:Free Radical Scavengers; D002563:Cerium; D009569:Nitric Oxide; C030583:ceric oxide