title: In utero treatment of fetal goitrous hypothyroidism in a euthyroid mother: a case report.
abstract: Fetal goitrous hypothyroidism is a rare condition in euthyroid pregnant women. Complications such as tracheal and esophageal compression with resultant polyhydramnios, as well as the possibility of neurodevelopmental effects of hypothyroidism, have prompted prenatal treatment with intra-amniotic L-thyroxine. We report a case of this condition and its in utero management.
authors.affiliation: Department of Obstetrics and Gynaecology, Groote Schuur Hospital, Cape Town, South Africa.
authors.forename: Chantal J M
authors.initials: CJ
authors.lastname: Stewart
authors.forename: Sonia
authors.initials: S
authors.lastname: Constantatos
authors.forename: Yaseen
authors.initials: Y
authors.lastname: Joolay
authors.forename: Linnie
authors.initials: L
authors.lastname: Muller
mesh_terms: D000293:Adolescent; D005260:Female; D005315:Fetal Diseases / Q000000981:diagnostic imaging* / Q000188:drug therapy; D005500:Follow-Up Studies; D006042:Goiter / Q000150:complications / Q000000981:diagnostic imaging* / Q000188:drug therapy; D006801:Humans; D007037:Hypothyroidism / Q000150:complications / Q000000981:diagnostic imaging* / Q000188:drug therapy; D011247:Pregnancy; D013961:Thyroid Gland / Q000000981:diagnostic imaging; D013974:Thyroxine / Q000627:therapeutic use; D018615:Ultrasonography, Doppler, Color / Q000379:methods; D016216:Ultrasonography, Prenatal / Q000379:methods*
chemical_list: D013974:Thyroxine