title: Coumarin-based chiral fluorescence sensor incorporating a thiourea unit for highly enantioselective recognition of N-Boc-protected proline.
abstract: New coumarin-based chiral thiourea sensor 1 was found to be an enantioselective fluorescent chemosensor for N-Boc-protected proline. The chiral sensor shows lower background fluorescence, and higher fluorescence enhancement with 18 nm blue shifts. Job plot analysis result indicates that sensor 1 can form a 1 : 1 stoichiometric complex and it could be used as a fluorescence sensor for the determination of enantiomer composition of N-Boc-protected proline.
authors.affiliation: State Key Laboratory of Coordination Chemistry, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, PR China.
authors.forename: Zhitao
authors.initials: Z
authors.lastname: Xing
authors.forename: Yong
authors.initials: Y
authors.lastname: Fu
authors.forename: Jiecong
authors.initials: J
authors.lastname: Zhou
authors.forename: Chengjian
authors.initials: C
authors.lastname: Zhu
authors.forename: Yixiang
authors.initials: Y
authors.lastname: Cheng
mesh_terms: D003374:Coumarins / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000737:chemistry*; D015394:Molecular Structure; D011392:Proline / Q000032:analysis / Q000737:chemistry; D013237:Stereoisomerism; D013890:Thiourea / Q000737:chemistry*
chemical_list: D003374:Coumarins; D005456:Fluorescent Dyes; D011392:Proline; C030123:coumarin; D013890:Thiourea