title: Functionalized nanostructures with application in regenerative medicine.
abstract: In the last decade, both regenerative medicine and nanotechnology have been broadly developed leading important advances in biomedical research as well as in clinical practice. The manipulation on the molecular level and the use of several functionalized nanoscaled materials has application in various fields of regenerative medicine including tissue engineering, cell therapy, diagnosis and drug and gene delivery. The themes covered in this review include nanoparticle systems for tracking transplanted stem cells, self-assembling peptides, nanoparticles for gene delivery into stem cells and biomimetic scaffolds useful for 2D and 3D tissue cell cultures, transplantation and clinical application.
authors.affiliation: Department of Health Sciences, University of Jaén, Jaén E-23071, Spain.
authors.forename: Macarena
authors.initials: M
authors.lastname: Perán
authors.affiliation: Research Unit, Hospital Universitario Virgen de las Nieves, Granada E-18014, Spain.
authors.forename: María A
authors.initials: MA
authors.lastname: García
authors.affiliation: Department of Health Sciences, University of Jaén, Jaén E-23071, Spain.
authors.forename: Elena
authors.initials: E
authors.lastname: López-Ruiz
authors.affiliation: Biosciences Institute, University College Cork, Cork, Ireland.
authors.forename: Milán
authors.initials: M
authors.lastname: Bustamante
authors.affiliation: Biopathology and Regenerative Medicine Institute (IBIMER), Biomedical Research Centre, University of Granada, Granada E-18100, Spain.
authors.forename: Gema
authors.initials: G
authors.lastname: Jiménez
authors.affiliation: Department of Biomedical Sciences, University of Sassari, 07100 Sassari, Italy.
authors.forename: Roberto
authors.initials: R
authors.lastname: Madeddu
authors.affiliation: Biopathology and Regenerative Medicine Institute (IBIMER), Biomedical Research Centre, University of Granada, Granada E-18100, Spain.|Department of Human Anatomy and Embryology, Faculty of Medicine, University of Granada, Granada E-18012, Spain.
authors.forename: Juan A
authors.identifier: 0000-0002-4996-8261
authors.initials: JA
authors.lastname: Marchal
mesh_terms: D001672:Biocompatible Materials / Q000627:therapeutic use; D001861:Bone Regeneration; D002356:Cartilage / Q000378:metabolism; D064987:Cell- and Tissue-Based Therapy / Q000379:methods*; D016503:Drug Delivery Systems / Q000379:methods*; D018014:Gene Transfer Techniques; D006801:Humans; D049329:Nanostructures / Q000627:therapeutic use*; D036103:Nanotechnology; D044968:Regenerative Medicine; D033581:Stem Cell Transplantation; D023822:Tissue Engineering / Q000379:methods*; D054457:Tissue Scaffolds
chemical_list: D001672:Biocompatible Materials