title: Targeting leucine addiction and autophagy in melanoma.
authors.affiliation: mdmeco@sanfordburnham.org
authors.forename: Maria T
authors.initials: MT
authors.lastname: Diaz-Meco
mesh_terms: D000818:Animals; D017209:Apoptosis; D001343:Autophagy / Q000235:genetics / Q000502:physiology*; D006801:Humans; D007930:Leucine / Q000378:metabolism*; D000076222:Mechanistic Target of Rapamycin Complex 1; D008544:Melanocytes / Q000378:metabolism; D008545:Melanoma / Q000188:drug therapy / Q000235:genetics / Q000378:metabolism* / Q000473:pathology; D051379:Mice; D008928:Mitochondria / Q000378:metabolism; D020929:Mitogen-Activated Protein Kinase Kinases / Q000378:metabolism; D046912:Multiprotein Complexes; D011506:Proteins / Q000235:genetics / Q000378:metabolism; D015398:Signal Transduction; D012878:Skin Neoplasms / Q000188:drug therapy / Q000235:genetics / Q000378:metabolism* / Q000473:pathology; D058570:TOR Serine-Threonine Kinases; D014407:Tumor Cells, Cultured; D018631:ras Proteins / Q000378:metabolism
chemical_list: D046912:Multiprotein Complexes; D011506:Proteins; D000076222:Mechanistic Target of Rapamycin Complex 1; D058570:TOR Serine-Threonine Kinases; D020929:Mitogen-Activated Protein Kinase Kinases; D018631:ras Proteins; D007930:Leucine