title: NOTES: basic and advanced surgical applications outside of the urological field.
abstract: Ten years ago the American gastroenterologist Anthony Kalloo described for the first time the concept of Natural Orifice Transluminal Endoscopic Surgery - NOTES. His  revolutionary vision generated such an unprecedented worldwide momentum of creativity and renovation in the surgical community to push the current limit of the  research in the minimal invasive surgery field toward the unimaginable goal of non visible scar surgery. At present time several NOTES applications are continuously  reported by many teams all around the world and the aim of the present paper was to illustrate the clinical evidence registered up to now as well as to inform about the ongoing research  efforts made to perform non visible scar surgery to treat more complex surgical diseases.
authors.affiliation: AIMS, Advanced International Mini-Invasive Surgery Academy, Milan, Italy. antonello.forgione@aimsacademy.org
authors.forename: Antonello
authors.initials: A
authors.lastname: Forgione
authors.forename: Ricardo
authors.initials: R
authors.lastname: Zorron
mesh_terms: D003106:Colon / Q000601:surgery; D004724:Endoscopy / Q000639:trends*; D016099:Endoscopy, Gastrointestinal / Q000639:trends; D004931:Esophageal Achalasia / Q000601:surgery; D013509:Gynecologic Surgical Procedures / Q000639:trends; D006801:Humans; D019060:Minimally Invasive Surgical Procedures / Q000639:trends*; D015337:Multicenter Studies as Topic; D057605:Natural Orifice Endoscopic Surgery / Q000009:adverse effects / Q000379:methods* / Q000639:trends*; D009367:Neoplasm Staging / Q000295:instrumentation / Q000379:methods; D010280:Parathyroid Glands / Q000601:surgery; D012187:Retroperitoneal Space / Q000601:surgery; D013270:Stomach / Q000601:surgery; D013961:Thyroid Gland / Q000601:surgery; D013520:Urologic Surgical Procedures / Q000639:trends*