title: Congenital infantile fibrosarcoma in a very low-birth-weight infant.
abstract: We describe a prenatally diagnosed case with congenital infantile fibrosarcoma, which is a rare malignant tumor, of which there have been only 14 cases reported in the English literature. A giant mass on the left thigh was detected at 24 weeks' gestation by prenatal ultrasonography. Because of its rapid growth and nonreassuring fetal status in utero, the baby was delivered by cesarean delivery at 27 weeks' gestation. The case was complicated by hemorrhagic anemia, coagulopathy, and cardiac failure, and a tumor resection was performed on day 3. As of age 2.5 years, he was healthy without evidence of recurrence. Because some fetal cases with congenital infantile fibrosarcoma have a poor prognosis, termination of pregnancy at an appropriate time and postnatal early treatment are crucial for successful treatment.
authors.affiliation: Perinatal Center, University of Miyazaki Hospital, Miyazaki University School of Medicine, Miyazaki, Japan. mukai2929@m3.kufm.kagoshima-u.ac.jp
authors.forename: Motoi
authors.initials: M
authors.lastname: Mukai
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Sameshima
authors.forename: Yuki
authors.initials: Y
authors.lastname: Kodama
authors.forename: Rie
authors.initials: R
authors.lastname: Yamashita
authors.forename: Masatoki
authors.initials: M
authors.lastname: Kaneko
authors.forename: Tsuyomu
authors.initials: T
authors.lastname: Ikenoue
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Matsufuji
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Kondo
authors.forename: Kazuo
authors.initials: K
authors.lastname: Chijiiwa
mesh_terms: D000328:Adult; D002585:Cesarean Section; D005260:Female; D005315:Fetal Diseases / Q000000981:diagnostic imaging* / Q000601:surgery; D005354:Fibrosarcoma / Q000151:congenital / Q000000981:diagnostic imaging* / Q000601:surgery; D006801:Humans; D007231:Infant, Newborn; D019102:Infant, Very Low Birth Weight; D008297:Male; D011247:Pregnancy; D012983:Soft Tissue Neoplasms / Q000151:congenital / Q000000981:diagnostic imaging* / Q000601:surgery; D013848:Thigh; D016216:Ultrasonography, Prenatal