title: Risk factors for intestinal invasive amebiasis in Japan, 2003-2009.
abstract: We determined yearly change in prevalence and risk factors for amebic colitis caused by intestinal invasive amebiasis among persons who underwent endoscopy and assessed differences between HIV-positive and HIV-negative persons in Japan. A total of 10,930 patients were selected for analysis, of whom 54 had amebic colitis. Prevalence was in 2009 (0.88%, 12/1360) compared with 2003 (0.16%, 3/1904). Male sex (odds ratio [OR] 8.39, 95% CI 1.99-35.40), age <50 years (OR 4.73, 95% CI 2.43-9.20), history of syphilis (OR 2.90, 95% CI 1.40-5.99), and HIV infection (OR 15.85, 95% CI 7.93-31.70) were independent risk factors. No differences in risk factors were identified between HIV-positive and HIV-negative patients. Contact with commercial sex workers was a new risk factor among HIV-negative patients. Homosexual intercourse, rather than immunosuppressed status, appears to be a risk factor among HIV-positive patients.
authors.affiliation: National Center for Global Health and Medicine, Tokyo, Japan. nnagata_ncgm@yahoo.co.jp
authors.forename: Naoyoshi
authors.initials: N
authors.lastname: Nagata
authors.forename: Takuro
authors.initials: T
authors.lastname: Shimbo
authors.forename: Junichi
authors.initials: J
authors.lastname: Akiyama
authors.forename: Ryo
authors.initials: R
authors.lastname: Nakashima
authors.forename: So
authors.initials: S
authors.lastname: Nishimura
authors.forename: Tomoyuki
authors.initials: T
authors.lastname: Yada
authors.forename: Koji
authors.initials: K
authors.lastname: Watanabe
authors.forename: Shinichi
authors.initials: S
authors.lastname: Oka
authors.forename: Naomi
authors.initials: N
authors.lastname: Uemura
mesh_terms: D000328:Adult; D060085:Coinfection; D004404:Dysentery, Amebic / Q000453:epidemiology* / Q000635:transmission; D005260:Female; D006679:HIV Seropositivity; D015497:HIV-1 / Q000276:immunology; D006801:Humans; D007564:Japan / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012307:Risk Factors