title: [Determination of phthalate plasticizers in foods by high performance liquid chromatography with gel permeation chromatographic clean-up].
abstract: A method of gel permeation chromatography-high performance liquid chromatography (GPC-HPLC) was established for the simultaneous determination of 5 main phthalate plasticizers in foods (edible oil, instant noodles, fried pastries, Saqima, etc.). The samples were extracted with petroleum ether in an ultrasonator, purified by a GPC column, and analyzed by HPLC. The chromatographic separation was achieved on a Labtech-C18 column (250 mm x 4.6 mm, 5 microm) using acetonitrile and water mixture as the mobile phases in a gradient elution mode. The developed method exhibited a linear correlation coefficient of more than 0.997 and the detection limits of 3.25 - 13.4 microg/L. The spike recoveries were between 70.4% and 113.6% with the relative standard deviations (RSDs, n = 3) of 0.3% - 5.8% at the spiked level of 50 mg/L. This method is simple, rapid and practical, and can be used for the simultaneous determination of PAEs in grease food samples.
authors.affiliation: Beijing Labtech Group, Beijing 101312, China.
authors.forename: Chunyu
authors.initials: C
authors.lastname: Zhang
authors.forename: Hui
authors.initials: H
authors.lastname: Wang
authors.forename: Xiaohui
authors.initials: X
authors.lastname: Zhang
authors.forename: Zhongqiang
authors.initials: Z
authors.lastname: Ma
authors.forename: Wanmei
authors.initials: W
authors.lastname: Deng
authors.forename: Ke
authors.initials: K
authors.lastname: Hu
authors.forename: Mingyu
authors.initials: M
authors.lastname: Ding
mesh_terms: D002850:Chromatography, Gel; D002851:Chromatography, High Pressure Liquid; D005506:Food Contamination / Q000032:analysis*; D010795:Phthalic Acids / Q000032:analysis*; D010968:Plasticizers / Q000032:analysis*
chemical_list: D010795:Phthalic Acids; D010968:Plasticizers; C032279:phthalic acid