title: Comparative analysis of caffeoylquinic acids and lignans in roots and seeds among various burdock (Arctium lappa) genotypes with high antioxidant activity.
abstract: Caffeoylquinic acids and lignans in the crude extracts of both roots and seeds from different burdock ( Arctium lappa  L.) genotypes were simultaneously characterized and systematically compared by LC-MS and matrix-assisted laser desorption/ionization quadrupole ion trap time-of-flight mass spectrometry (MALDI-QIT-TOF MS), and their antioxidant activities were also investigated. A total of 14 lignans were identified in burdock seeds and 12 caffeoylquinic acids in burdock roots. High levels of caffeoylquinic acids were also detected in burdock seeds, but only trace amounts of lignans were found in burdock roots. Burdock seeds contained higher concentrations of lignans and caffeoylquinic acids than burdock roots. Quantitative analysis of caffeoylquinic acids and lignans in roots and seeds of various burdock genotypes was reported for the first time. Great variations in contents of both individual and total phenolic compounds as well as antioxidant activities were found among different genotypes. Burdock as a root vegetable or medicinal plants possessed considerably stronger antioxidant activity than common vegetables and fruits.
authors.affiliation: School of Chinese Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, China.
authors.forename: Jingyi
authors.initials: J
authors.lastname: Liu
authors.forename: Yi-Zhong
authors.initials: YZ
authors.lastname: Cai
authors.forename: Ricky Ngok Shun
authors.initials: RN
authors.lastname: Wong
authors.forename: Calvin Kai-Fai
authors.initials: CK
authors.lastname: Lee
authors.forename: Sydney Chi Wai
authors.initials: SC
authors.lastname: Tang
authors.forename: Stephen Cho Wing
authors.initials: SC
authors.lastname: Sze
authors.forename: Yao
authors.initials: Y
authors.lastname: Tong
authors.forename: Yanbo
authors.initials: Y
authors.lastname: Zhang
mesh_terms: D000975:Antioxidants / Q000032:analysis* / Q000378:metabolism; D031170:Arctium / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism; D005838:Genotype; D017705:Lignans / Q000032:analysis* / Q000378:metabolism; D010936:Plant Extracts / Q000032:analysis* / Q000378:metabolism; D018517:Plant Roots / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism; D011801:Quinic Acid / Q000031:analogs & derivatives* / Q000032:analysis / Q000378:metabolism; D012639:Seeds / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism
chemical_list: D000975:Antioxidants; D017705:Lignans; D010936:Plant Extracts; C472707:caffeoylquinic acid; D011801:Quinic Acid