title: [Photodegradation of atenolol in aqueous nitrate solution].
abstract: The aqueous photolysis of beta-blocker atenolol (ATL) using Xe lamp as simulated solar irradiation source was investigated in the presence of nitrate ions. The effects of nitrate ion concentration, solution pH value, and concentration of bicarbonate and humic substance on the photodegradation of ATL were studied. The results showed that photodegradation of ATL in nitrate solution followed pseudo-first-order kinetics. The increasing concentration of nitrate ion promoted the photodegradation rate of ATL. The first-order rate constant increased from 0.002 26 min(-1) to 0.009 4 min(-1) with nitrate concentration increasing from 0 to 5 mmol x L(-1). Acidic or alkaline condition of the solution favored the photodegradation of ATL. Different concentration of bicarbonate showed insignificant effect of the degradation while the increasing concentration of fulvic acid showed inhibiting effect. Hydroxyl radical was determined to be formed during the photolysis process of ATL using isopropanol as molecular probe. The main photoproducts of ATL were identified by using SPE-LC-MS techniques and possible photoinduced degradation pathways in nitrate solution were proposed.
authors.affiliation: State Key Laboratory of Pollution Control and Resource Reuse, School of the Environment, Nanjing University, Nanjing 210046, China. jiyuefei2731@126.com
authors.forename: Yue-Fei
authors.initials: YF
authors.lastname: Ji
authors.forename: Chao
authors.initials: C
authors.lastname: Zeng
authors.forename: Cui
authors.initials: C
authors.lastname: Meng
authors.forename: Xi
authors.initials: X
authors.lastname: Yang
authors.forename: Shi-Xiang
authors.initials: SX
authors.lastname: Gao
mesh_terms: D058671:Adrenergic beta-1 Receptor Antagonists / Q000737:chemistry / Q000302:isolation & purification; D001262:Atenolol / Q000737:chemistry* / Q000302:isolation & purification*; D009566:Nitrates / Q000737:chemistry*; D010782:Photolysis; D012996:Solutions; D014874:Water Pollutants, Chemical / Q000737:chemistry / Q000302:isolation & purification*
chemical_list: D058671:Adrenergic beta-1 Receptor Antagonists; D009566:Nitrates; D012996:Solutions; D014874:Water Pollutants, Chemical; D001262:Atenolol