title: Effects of chronic lead exposure on functions of nervous system in Chinese children and developmental rats.
abstract: Lead pollution is a very serious problem in China with the rapid economic development. A large amount of lead has been released into the environment due to mineral processing activities and has impacted water resources, soils, vegetables, and crops. The gasoline with lead has been banned in China since July 1, 2000. Though a noticeable decrease of lead poisoning rates has been evidenced, the children's blood lead levels are still significantly higher than those in developed countries. Therefore, lowering the lead exposure in childhood continues to be an important public health objective in China. There is also a lot that remains to be done to reduce children's exposure to lead. In this section, five scientists from China presented latest research results regarding the current situation of lead poisoning in China, the mechanisms involved in lead-induced neurotoxicity, and the new advances related to the potential therapy methods. Their researches may pave new way not only for the prevention of lead poisoning but also for the treatment of affected children in China and other countries.
authors.affiliation: Department of Occupational and Environmental Health and the Ministry of Education Key Lab of Hazard Assessment and Control in Special Operational Environment, School of Public Health, Fourth Military Medical University, Xi'an 710032, China.
authors.forename: Wenjing
authors.initials: W
authors.lastname: Luo
authors.forename: Diyun
authors.initials: D
authors.lastname: Ruan
authors.forename: Chonghuai
authors.initials: C
authors.lastname: Yan
authors.forename: Shuting
authors.initials: S
authors.lastname: Yin
authors.forename: Jingyuan
authors.initials: J
authors.lastname: Chen
mesh_terms: D000367:Age Factors; D000818:Animals; D044466:Asian People; D001812:Blood-Brain Barrier / Q000187:drug effects / Q000378:metabolism / Q000503:physiopathology; D002648:Child; D002657:Child Development / Q000187:drug effects*; D002681:China / Q000453:epidemiology; D004195:Disease Models, Animal; D004781:Environmental Exposure / Q000009:adverse effects*; D004785:Environmental Pollutants / Q000009:adverse effects*; D006801:Humans; D007854:Lead / Q000009:adverse effects*; D020264:Lead Poisoning, Nervous System, Childhood / Q000208:ethnology / Q000209:etiology* / Q000378:metabolism / Q000503:physiopathology; D009420:Nervous System / Q000187:drug effects* / Q000254:growth & development / Q000378:metabolism / Q000503:physiopathology; D009457:Neuroglia / Q000187:drug effects / Q000378:metabolism; D009473:Neuronal Plasticity / Q000187:drug effects; D051381:Rats; D018570:Risk Assessment; D012307:Risk Factors; D009435:Synaptic Transmission / Q000187:drug effects; D013997:Time Factors
chemical_list: D004785:Environmental Pollutants; D007854:Lead