title: [µ-opioid receptors in the central nucleus of the amygdala modulate sucrose solution intake in rats].
abstract: OBJECTIVE
  To explore the role of µ-opioid receptors (MOR) in the central nucleus of the amygdala (CeA) in modulating sucrose solution intake in rats.
  
  
  METHODS
  Sprague-Dawley rats received intra-CeA injection of MOR agonist DAMGO or saline, and then underwent two bottle choice test between sucrose solution and distilled water. After intake of sucrose solution or distilled water, activated neurons in the CeA were labeled and identified with MOR/Fos-double labeling immunohistochemistry.
  
  
  RESULTS
  Compared with saline injection, intra-CeA injection of DAMGO significantly increased sucrose solution intake in rats over a 3-h period. Sucrose solution intake induced significantly more c-Fos and MOR/Fos double-labeled neurons in the CeA than distilled water intake.
  
  
  CONCLUSIONS
  The CeA participates in modulation of sucrose intake in rats, and MOR may partly mediate this mechanism.
authors.affiliation: Department of Physiology and Pathophysiology, Key Laboratory of Environment and Genes Related to Diseases, Ministry of Education, Xi'an Jiaotong University School of Medicine, Xi'an 710061, China. sunbo.1217@gmail.com
authors.forename: Bo
authors.initials: B
authors.lastname: Sun
authors.forename: Jianqun
authors.initials: J
authors.lastname: Yan
authors.forename: Qian
authors.initials: Q
authors.lastname: Wang
authors.forename: Xiaolin
authors.initials: X
authors.lastname: Zhao
authors.forename: Jinrong
authors.initials: J
authors.lastname: Li
authors.forename: Wei
authors.initials: W
authors.lastname: Yan
authors.forename: Ke
authors.initials: K
authors.lastname: Chen
authors.forename: Xuejuan
authors.initials: X
authors.lastname: Yang
authors.forename: Shiru
authors.initials: S
authors.lastname: Zhao
authors.forename: Junbao
authors.initials: J
authors.lastname: Yan
mesh_terms: D000679:Amygdala / Q000378:metabolism*; D000818:Animals; D008297:Male; D009474:Neurons / Q000378:metabolism*; D051381:Rats; D017207:Rats, Sprague-Dawley; D017450:Receptors, Opioid, mu / Q000378:metabolism*; D013395:Sucrose / Q000378:metabolism*
chemical_list: D017450:Receptors, Opioid, mu; D013395:Sucrose