title: Molecular cytogenetic characterization of undifferentiated embryonal sarcoma of the liver: a case report and literature review.
abstract: Undifferentiated embryonal sarcoma of the liver (UESL) represents a heterogeneous group of tumors derived from mesenchymal tissues. Earlier cytogenetic studies in limited cases demonstrated that UESL is associated with a recurrent translocation t(11;19)(q11;q13.3-q13.4) or add(19)(q13.4). In this report, we present our array comparative genomic hybridization (aCGH), fluorescence in situ hybridization (FISH) findings, and a missense mutation of TP53 gene by DNA sequencing in a 19-year-old patient with UESL. The data were compared to laboratory findings reported by previous studies.
authors.affiliation: Department of Internal Medicine, The First Hospital of Jilin University, Jilin 130021, China. junqiniu@yahoo.com.cn.
authors.forename: Xiaoxia
authors.initials: X
authors.lastname: Hu
authors.forename: Haiying
authors.initials: H
authors.lastname: Chen
authors.forename: Meishan
authors.initials: M
authors.lastname: Jin
authors.forename: Xianfu
authors.initials: X
authors.lastname: Wang
authors.forename: Jiyun
authors.initials: J
authors.lastname: Lee
authors.forename: Weihong
authors.initials: W
authors.lastname: Xu
authors.forename: Rui
authors.initials: R
authors.lastname: Zhang
authors.forename: Shibo
authors.initials: S
authors.lastname: Li
authors.forename: Junqi
authors.initials: J
authors.lastname: Niu