title: Comparative findings in childhood-onset versus adult-onset optic disc pit maculopathy.
abstract: OBJECTIVE
  To compare the clinical characteristics of eyes with childhood-onset to those with adult-onset optic disc pit maculopathy.
  
  
  METHODS
  Twenty-seven eyes of 25 patients with optic disc pit maculopathy were reviewed. The clinical characteristics, clinical history including a history of blunt trauma, ophthalmoscopic evaluations and intraoperative findings in the childhood-onset (age <15 years, four eyes of four patients) cases were compared with those in the adult-onset (≥15 years, 23 eyes of 21 patients) cases of optic disc pit maculopathy. The strength of the vitreous adhesions was graded by what was required to create a posterior vitreous detachment (PVD); grade 1 = with vitreous cutter, grade 2 = by microhook or forceps and grade 3 = by forceps with removal of remnants of Cloquet's canal.
  
  
  RESULTS
  The incidence of visual impairments following blunt trauma was significantly higher in childhood-onset (three of four eyes) than that of adult-onset (0 of 23 eyes, p = 0.0014). Vitreous surgery with creation of a PVD was performed in the four childhood-onset eyes and 18 adult-onset eyes after an absence of a spontaneous resolution. The grade of the vitreous adhesions was significantly higher in childhood-onset than in adult-onset eyes (p = 0.0096).
  
  
  CONCLUSIONS
  An ocular trauma may provide an opportunity to detect optic disc pits. However, childhood-onset optic disc pit maculopathy was noted most commonly following blunt ocular trauma in eyes with a strong vitreous adhesion to the optic disc margin.
authors.affiliation: Kyorin Eye Center, Kyorin University School of Medicine, Tokyo, Japan.
authors.forename: Tosho
authors.initials: T
authors.lastname: Rii
authors.forename: Akito
authors.initials: A
authors.lastname: Hirakata
authors.forename: Makoto
authors.initials: M
authors.lastname: Inoue
mesh_terms: D000293:Adolescent; D000328:Adult; D017668:Age of Onset; D002648:Child; D003937:Diagnosis, Differential; D005131:Eye Injuries / Q000150:complications* / Q000175:diagnosis / Q000453:epidemiology; D005260:Female; D006801:Humans; D015994:Incidence; D007564:Japan / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D009887:Ophthalmoscopy; D009898:Optic Disk / Q000293:injuries / Q000473:pathology*; D009901:Optic Nerve Diseases / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology*; D015995:Prevalence; D014786:Vision Disorders / Q000175:diagnosis / Q000453:epidemiology* / Q000209:etiology; D014822:Vitreous Body / Q000473:pathology; D014949:Wounds, Nonpenetrating / Q000150:complications* / Q000175:diagnosis / Q000453:epidemiology; D055815:Young Adult