title: The role of lipophilicity in transmembrane anion transport.
abstract: The transmembrane anion transport activity of a series of synthetic molecules inspired by the structure of tambjamine alkaloids can be tuned by varying the lipophilicity of the receptor, with carriers within a certain log P range performing best.
authors.affiliation: Centre for Systems Chemistry, Stratingh Institute, University of Groningen, 9747 AG Groningen, The Netherlands.
authors.forename: Vittorio
authors.initials: V
authors.lastname: Saggiomo
authors.forename: Sijbren
authors.initials: S
authors.lastname: Otto
authors.forename: Igor
authors.initials: I
authors.lastname: Marques
authors.forename: Vítor
authors.initials: V
authors.lastname: Félix
authors.forename: Tomás
authors.initials: T
authors.lastname: Torroba
authors.forename: Roberto
authors.initials: R
authors.lastname: Quesada
mesh_terms: D000838:Anions / Q000737:chemistry / Q000378:metabolism*; D001688:Biological Products / Q000737:chemistry / Q000378:metabolism; D057927:Hydrophobic and Hydrophilic Interactions; D017136:Ion Transport; D008051:Lipid Bilayers / Q000737:chemistry / Q000378:metabolism*; D010713:Phosphatidylcholines / Q000737:chemistry
chemical_list: D000838:Anions; D001688:Biological Products; D008051:Lipid Bilayers; D010713:Phosphatidylcholines; C028694:1-palmitoyl-2-oleoylphosphatidylcholine