title: The role of vitamin D in asthma.
abstract: Vitamin D metabolites are important immune-modulatory hormones and are able to suppress Th2-mediated allergic airway disease. Some genetic factors that may contribute to asthma are regulated by vitamin D, such as vitamin D receptor (VDR), human leukocyte antigen genes (HLA), human Toll-like receptors (TLR), matrix metalloproteinases (MMPs), a disintegrin and metalloprotein-33 (ADAM-33), and poly(ADP-ribosyl) polymerase- 1 (PARP-1). Vitamin D has also been implicated in asthma through its effects on the obesity, bacillus Calmettee Guérin (BCG) vaccination and high vitamin D level, vitamin D supplement, checkpoint protein kinase 1 (Chk1), plasminogen activator inhibitor-1 (PAI-1) and gamma delta T cells (gdT). Vitamin D plays a role in asthma and exerts its action through either genomic and/or non-genomic ways.
authors.affiliation: Vietnamese American Medical Research Foundation, Westminster, CA, USA. Lng2687765@aol.com
authors.forename: Khanh vinh quoc
authors.initials: Kv
authors.lastname: Luong
authors.forename: Lan Thi Hoàng
authors.initials: LT
authors.lastname: Nguyen
mesh_terms: D000818:Animals; D001249:Asthma / Q000235:genetics / Q000276:immunology / Q000503:physiopathology*; D002117:Calcitriol / Q000008:administration & dosage; D019587:Dietary Supplements; D023281:Genomics / Q000379:methods; D006801:Humans; D018418:Th2 Cells / Q000276:immunology*; D014807:Vitamin D / Q000008:administration & dosage / Q000378:metabolism*; D014815:Vitamins / Q000008:administration & dosage / Q000378:metabolism
chemical_list: D014815:Vitamins; D014807:Vitamin D; D002117:Calcitriol