title: Stress transient hypertrophic cardiomyopathy and B-type natriuretic peptide role.
abstract: This report describes a transient hypertrophic cardiomyopathy with right-ventricle outlet tract obstruction (RVOTO) induced by perinatal stress due to a major surgical procedure in a female newborn with congenital abnormalities. On day 10, she presented with heart failure, abnormal B-type natriuretic peptide (BNP), and an echocardiogram showing normal wall thickness. An in-hospital follow-up echocardiogram showed biventricular hypertrophy and RVOTO. At discharge, the infant was asymptomatic, with a normal echocardiogram and BNP. Transient RVOTO triggered by surgical stress and abnormal BNP have not been reported previously. Pathophysiology, the role of BNP, and clinical characteristics are discussed.
authors.affiliation: Pediatric Cardiology Department, Instituto de Cardiologia y Medicina Vascular del Tec de Monterrey, Monterrey, NL, Mexico.
authors.forename: Jesus
authors.initials: J
authors.lastname: Yañez
authors.forename: David
authors.initials: D
authors.lastname: Rodriguez
authors.forename: Cristina
authors.initials: C
authors.lastname: Treviño
authors.forename: Adriana
authors.initials: A
authors.lastname: Valdez
authors.forename: Carlos
authors.initials: C
authors.lastname: Jerjes-Sanchez
mesh_terms: D000015:Abnormalities, Multiple / Q000175:diagnosis / Q000601:surgery*; D001034:Apgar Score; D015415:Biomarkers / Q000097:blood; D002312:Cardiomyopathy, Hypertrophic / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000628:therapy*; D002585:Cesarean Section; D003131:Combined Modality Therapy; D015150:Echocardiography, Doppler; D004562:Electrocardiography / Q000379:methods; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006849:Hydrocephalus / Q000175:diagnosis / Q000601:surgery; D007231:Infant, Newborn; D008591:Meningomyelocele / Q000175:diagnosis / Q000601:surgery; D020097:Natriuretic Peptide, Brain / Q000032:analysis / Q000378:metabolism*; D018570:Risk Assessment; D016135:Spinal Dysraphism / Q000175:diagnosis / Q000601:surgery; D054549:Takotsubo Cardiomyopathy / Q000000981:diagnostic imaging* / Q000503:physiopathology / Q000628:therapy*; D016896:Treatment Outcome; D016216:Ultrasonography, Prenatal / Q000379:methods; D014694:Ventricular Outflow Obstruction / Q000000981:diagnostic imaging* / Q000503:physiopathology / Q000628:therapy
chemical_list: D015415:Biomarkers; D020097:Natriuretic Peptide, Brain