title: Mycobacterium DNA detection in liver and skin of a horse with generalized sarcoidosis.
abstract: Sarcoidosis is a rare equine skin disease characterized primarily by an exfoliative and granulomatous dermatitis but also presenting granulomatous inflammation of multiple systems. The current report presents the clinical and histopathological findings of sarcoidosis in a 16-year-old American Quarter Horse gelding with nested polymerase chain reaction Mycobacterium spp. DNA detection within hepatic and skin samples. Mycobacterium spp. may play a role in the pathogenesis of equine sarcoidosis as has been proposed for human sarcoidosis.
authors.affiliation: Department of Veterinary Clinical Science, College of Veterinary Medicine and Animal Science of the Univ Estadual Paulista - UNESP, Botucatu, SP, Brazil.
authors.forename: José P
authors.initials: JP
authors.lastname: Oliveira-Filho
authors.forename: Lidianne N
authors.initials: LN
authors.lastname: Monteiro
authors.forename: Diego José Z
authors.initials: DJ
authors.lastname: Delfiol
authors.forename: Julio L
authors.initials: JL
authors.lastname: Sequeira
authors.forename: Rogério M
authors.initials: RM
authors.lastname: Amorim
authors.forename: Viciany E
authors.initials: VE
authors.lastname: Fabris
authors.forename: Fabio
authors.initials: F
authors.lastname: Del Piero
authors.forename: Alexandre S
authors.initials: AS
authors.lastname: Borges
mesh_terms: D000818:Animals; D004269:DNA, Bacterial / Q000737:chemistry / Q000235:genetics; D017809:Fatal Outcome; D006734:Horse Diseases / Q000382:microbiology* / Q000473:pathology; D006736:Horses; D007150:Immunohistochemistry / Q000662:veterinary; D008297:Male; D009161:Mycobacterium / Q000235:genetics / Q000302:isolation & purification*; D009164:Mycobacterium Infections / Q000382:microbiology / Q000473:pathology / Q000662:veterinary*; D016133:Polymerase Chain Reaction / Q000662:veterinary; D012507:Sarcoidosis / Q000382:microbiology / Q000473:pathology / Q000662:veterinary*; D012871:Skin Diseases / Q000382:microbiology / Q000473:pathology / Q000662:veterinary*
chemical_list: D004269:DNA, Bacterial