title: [Is calcium supplement useful in aged persons? Calcium supplement doesn't reduce the fracture and vascular risk in aged persons].
abstract: Although there are biologically plausible mechanisms by which calcium supplements reduce bone loss and lower rate of vertebral fracture in older persons, recent studies failed to demonstrate the effects of calcium supplements to reduce fracture risk. In addition, either observational or interventional studies showed that calcium supplements were associated with increase in myocardial infarction. Taken together, the reassessment of the role of calcium supplements for the prevention of osteoporosis and fracture should be warranted.
authors.affiliation: Department of Medicine and Biological Science, Gunma University Graduate School of Medicine, Japan.
authors.forename: Masahiko
authors.initials: M
authors.lastname: Kurabayashi
mesh_terms: D000368:Aged; D002136:Calcium, Dietary / Q000008:administration & dosage / Q000009:adverse effects*; D002318:Cardiovascular Diseases / Q000139:chemically induced*; D050723:Fractures, Bone / Q000517:prevention & control*; D006801:Humans; D010024:Osteoporosis / Q000517:prevention & control; D012307:Risk Factors
chemical_list: D002136:Calcium, Dietary