title: Reverse vesicle formation from the yeast glycolipid biosurfactant mannosylerythritol lipid-D.
abstract: Mannosylerythritol lipids (MELs) are secreted by yeasts and are promising glycolipid biosurfactants. In our study on the non-aqueous phase behaviors of MEL homologues, we found that MEL-D (4-O-[2',3'-di-O-alka(e)noyl-β-D-mannopyranosyl]-(2R,3S)-erythritol) forms aggregates in decane. The microscopic observation and the X-ray scattering measurement of these aggregates revealed that they are reverse vesicles that consist of bilayers whose hydrophilic domains are located in the interior of the bilayers. In addition, MEL-D formed reverse vesicles without co-surfactants and co-solvents in various oily solutions, such as n-alkanes, cyclohexane, squalane, squalene, and silicone oils at a concentration below 10 mM. This is the first report on the reverse vesicle formation from biosurfactants.
authors.affiliation: Research Institute for Innovation in Sustainable Chemistry, National Institute of Advanced Industrial Science and Technology-AIST, Tsukuba, Ibaraki 305-8565, Japan.
authors.forename: Tokuma
authors.initials: T
authors.lastname: Fukuoka
authors.forename: Takashi
authors.initials: T
authors.lastname: Yanagihara
authors.forename: Seya
authors.initials: S
authors.lastname: Ito
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Imura
authors.forename: Tomotake
authors.initials: T
authors.lastname: Morita
authors.forename: Hideki
authors.initials: H
authors.lastname: Sakai
authors.forename: Masahiko
authors.initials: M
authors.lastname: Abe
authors.forename: Dai
authors.initials: D
authors.lastname: Kitamoto
mesh_terms: D006017:Glycolipids / Q000737:chemistry*; D013501:Surface-Active Agents / Q000737:chemistry*; D014587:Ustilaginales / Q000737:chemistry*
chemical_list: D006017:Glycolipids; D013501:Surface-Active Agents; C575882:mannosylerythritol lipid-D