title: Accessing a small library of pluripotent 1,4,5-trisubstituted 1H-1,2,3-triazoles via diversity-oriented synthesis.
abstract: Diversity-oriented synthesis of structurally different, novel and small drug like molecules based on 1,4,5-trisubstituted 1,2,3-triazoles is developed in a streamlined sequence of different sets of reactions. The method involves the use of simple, readily available and highly economical substrates and reagents. The molecules developed herein have potential to be exploited either as chemotherapeutic agents or as scaffolds for other biologically active compounds.
authors.affiliation: Council of Scientific and Industrial Research, Lucknow, India.
authors.forename: Arya
authors.initials: A
authors.lastname: Ajay
authors.forename: Munna Prasad
authors.initials: MP
authors.lastname: Gupt
authors.forename: N
authors.initials: N
authors.lastname: Devender
authors.forename: Rama P
authors.initials: RP
authors.lastname: Tripathi
mesh_terms: D003500:Cyclization; D015394:Molecular Structure; D010091:Oximes / Q000138:chemical synthesis / Q000737:chemistry; D014230:Triazoles / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D010091:Oximes; D014230:Triazoles