title: DNA unzipping and protein unfolding using nanopores.
abstract: We present here an overview on unfolding of biomolecular structures as DNA double strands or protein folds. After some theoretical considerations giving orders of magnitude about transport timescales through pores, forces involved in unzipping processes … we present our experiments on DNA unzipping or protein unfolding using a nanopore. We point out the difficulties that can be encountered during these experiments, such as the signal analysis problems, noise issues, or experimental limitations of such system.
authors.affiliation: Laboratoire LAMBE (Equipe MPI) CNRS UMR 8587, Université d'Evry-val d'Essonne, Evry, France.
authors.forename: Céline
authors.initials: C
authors.lastname: Merstorf
authors.forename: Benjamin
authors.initials: B
authors.lastname: Cressiot
authors.forename: Manuela
authors.initials: M
authors.lastname: Pastoriza-Gallego
authors.forename: Abdel Ghani
authors.initials: AG
authors.lastname: Oukhaled
authors.forename: Laurent
authors.initials: L
authors.lastname: Bacri
authors.forename: Jacques
authors.initials: J
authors.lastname: Gierak
authors.forename: Juan
authors.initials: J
authors.lastname: Pelta
authors.forename: Loïc
authors.initials: L
authors.lastname: Auvray
authors.forename: Jérôme
authors.initials: J
authors.lastname: Mathé
mesh_terms: D000465:Algorithms; D001426:Bacterial Proteins / Q000737:chemistry; D001692:Biological Transport; D053841:Electroosmosis; D006460:Hemolysin Proteins / Q000737:chemistry; D058619:Maltose-Binding Proteins / Q000737:chemistry; D008567:Membranes, Artificial; D058608:Nanopores; D009691:Nucleic Acid Denaturation; D058767:Protein Unfolding
chemical_list: D001426:Bacterial Proteins; D006460:Hemolysin Proteins; D058619:Maltose-Binding Proteins; D008567:Membranes, Artificial