title: Augmented blood pressure measurement through the noninvasive estimation of physiological arterial pressure variability.
abstract: Current noninvasive blood pressure (BP) measurement methods, such as the oscillometric method, estimate the systolic and diastolic blood pressure (SBP and DBP) at two random instants in time and do not take into account the natural variability in BP. The standard for automated BP devices sets a maximum allowable system error of ±5 mmHg, even though natural BP variability often exceeds these limits. This paper proposes a new approach using simultaneous recordings of the oscillometric and continuous arterial pulse waveforms to augment the conventional noninvasive measurement by providing (1) the mean SBP and DBP over the measurement interval and the associated confidence intervals of the mean, (2) the standard deviation of SBP and DBP over the measurement interval, which indicates the degree of fluctuation in BP and (3) an indicator as to whether or not the oscillometric reading is an outlier. Recordings with healthy subjects demonstrate the potential utility of this approach to characterize BP, to detect outlier measurements, and that it does not suffer from bias relative to the conventional oscillometric method.
authors.affiliation: School of Electrical Engineering and Computer Science, University of Ottawa, 800 King Edward Ave, Ottawa, Ontario, Canada. ksoue063@eecs.uottawa.ca
authors.forename: Karen
authors.initials: K
authors.lastname: Soueidan
authors.forename: Silu
authors.initials: S
authors.lastname: Chen
authors.forename: Hilmi R
authors.initials: HR
authors.lastname: Dajani
authors.forename: Miodrag
authors.initials: M
authors.lastname: Bolic
authors.forename: Voicu
authors.initials: V
authors.lastname: Groza
mesh_terms: D000328:Adult; D001158:Arteries / Q000502:physiology*; D001794:Blood Pressure / Q000502:physiology*; D001795:Blood Pressure Determination / Q000295:instrumentation / Q000379:methods*; D002138:Calibration; D003971:Diastole / Q000502:physiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009991:Oscillometry; D011674:Pulse; D013599:Systole / Q000502:physiology; D058067:Wavelet Analysis; D055815:Young Adult