title: A clinical evaluation comparing two H2O2 concentrations used with a light-assisted chairside tooth whitening system.
abstract: The purpose of this study was to assess the efficacy of two different BriteSmile hydrogen peroxide (H2O2) gels in a split-arch protocol for whitening teeth in a clinical setting when used in conjunction with a BriteSmile BS4000 lamp. Fifteen subjects were enrolled into a single-center clinical trial. The efficacy of the BriteSmile BS4000 lamp using both 15% H2O2 and 25% H2O2 gel formulations was tested. Study subjects were concurrently exposed to the whitening lamp with the 15% H2O2 gel placed on half of their anterior teeth and the 25% H2O2 gel on the other half for a total light and gel exposure of 60 minutes. The clinical data collected were shade score, gingival health, and dentinal hypersensitivity self-assessment. Changes in tooth shade were better for subjects exposed to the 25% gel and the dental whitening lamp (average 8.0 shade changes) compared to subjects exposed to the 15% gel and dental whitening lamp (average 7.6 shade changes) immediately after treatment. The same held true at the 7-day follow-up (25% gel average 7.4 shade changes versus 15% gel average 7.3 shade changes). However, these differences were not statistically significant. No reports of irritation of gingival soft tissues were documented. The relative changes in mean sensitivity scores were similar for both groups with no significant differences in mean sensitivity scores between the groups. Both concentrations of H2O2 gel and the whitening lamp combined gave study subjects an average of 8.0 (25% gel) and 7.6 (15% gel) shade changes immediately after treatment. The 7-day follow-up examination resulted in a regression of lightest to an average of 7.4 (25% gel) and 7.3 (15% gel). It was concluded that the use of the chairside whitening light and either 15% or 25% hydrogen peroxide gel is safe and effective for whitening teeth in 1 hour.
authors.forename: Marilyn
authors.initials: M
authors.lastname: Ward
authors.forename: Heather
authors.initials: H
authors.lastname: Felix
mesh_terms: D000328:Adult; D000368:Aged; D003116:Color; D003481:Cuspid / Q000187:drug effects / Q000473:pathology; D003807:Dentin Sensitivity / Q000139:chemically induced; D005260:Female; D005500:Follow-Up Studies; D005782:Gels; D005881:Gingiva / Q000187:drug effects; D005891:Gingivitis / Q000139:chemically induced; D006801:Humans; D006861:Hydrogen Peroxide / Q000008:administration & dosage*; D007180:Incisor / Q000187:drug effects / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009061:Mouth Mucosa / Q000187:drug effects; D010778:Photochemotherapy / Q000295:instrumentation / Q000379:methods; D012449:Safety; D013997:Time Factors; D014073:Tooth Bleaching / Q000295:instrumentation / Q000379:methods*; D058205:Tooth Bleaching Agents / Q000008:administration & dosage*; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D005782:Gels; D058205:Tooth Bleaching Agents; D006861:Hydrogen Peroxide