title: A review of the utility of EEG depth of anaesthesia monitors in the paediatric intensive care environment.
abstract: OBJECTIVE
  This paper aims to bring together current evidence regarding the use of depth of anaesthesia monitors (DoAM) as objective measures of sedation for paediatric intensive care (PIC) patients.
  
  
  BACKGROUND
  Delivering appropriate dosages of sedative agents, to individual PIC patients, is important to reduce the many risks of over- or under-sedation. Although based on adult anaesthesia, DoAMs could offer increased objectivity to the titration of sedative agents for children in PIC. This article synthesises the current available evidence from studies investigating DoAM use in the PIC environment.
  
  
  METHODS
  Literature regarding DoAM use in PIC was reviewed, from 1996 and August 2011, after EMBASE, PubMed, CINAHL and ProQuest Dissertation & Theses Database were searched using key search terms.
  
  
  RESULTS
  Fourteen original research articles addressing sedation assessment using DoAMs in PIC were identified. The main findings were that DoAMs generally have a moderate or poor correlation with sedation scores and their performance varies in varying clinical settings. DoAMs do not make reliable conclusions about depth of sedation of individual PIC children, and can be influenced by children's age.
  
  
  CONCLUSIONS
  Evidence to support DoAMs in the PIC setting is currently not sufficient to advocate their routine use in clinical practice.
authors.affiliation: Department of Anaesthesia and Pain Management, Royal Children's Hospital, Melbourne, Australia. stephen.mckeever@rch.org.au
authors.forename: Stephen
authors.initials: S
authors.lastname: McKeever
authors.forename: Linda
authors.initials: L
authors.lastname: Johnston
authors.forename: Andrew
authors.initials: A
authors.lastname: Davidson
mesh_terms: D000293:Adolescent; D000777:Anesthetics / Q000008:administration & dosage*; D002648:Child; D002675:Child, Preschool; D016903:Drug Monitoring / Q000295:instrumentation / Q000379:methods*; D004569:Electroencephalography; D055317:Evidence-Based Practice; D006801:Humans; D006993:Hypnotics and Sedatives / Q000008:administration & dosage*; D007223:Infant; D007231:Infant, Newborn; D015278:Intensive Care Units, Pediatric
chemical_list: D000777:Anesthetics; D006993:Hypnotics and Sedatives