title: Diastereoselective synthesis of vicinal amino alcohols.
abstract: The vicinal amino alcohol is a common motif in natural products and pharmaceuticals. Amino acids constitute a natural, inexpensive, and enantiopure choice of starting material for the synthesis of such functionalities. However, the matters concerning diastereoselectivity are not obvious. This Perspective takes a look in the field of diastereoselective synthesis of vicinal amino alcohols starting from amino acids using various methods.
authors.affiliation: Department of Chemistry, Aalto University School of Chemical Technology, P.O. Box 16100 (Kemistintie 1), FI-00076 Aalto, Finland.
authors.forename: Oskari K
authors.initials: OK
authors.lastname: Karjalainen
authors.forename: Ari M P
authors.initials: AM
authors.lastname: Koskinen
mesh_terms: D000447:Aldehydes / Q000138:chemical synthesis; D000605:Amino Alcohols / Q000138:chemical synthesis*; D005960:Glucosides / Q000737:chemistry*; D015394:Molecular Structure; D010084:Oxidation-Reduction; D011744:Pyrimidinones / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000447:Aldehydes; D000605:Amino Alcohols; D005960:Glucosides; D011744:Pyrimidinones; C009661:vicine