title: Advances in apoptotic mediated proteolysis in meat tenderisation.
abstract: Meat tenderness is considered to be one of the most important attributes of meat quality; however it is also one of the most variable. Ultimate meat tenderness is influenced by the amount of intramuscular connective tissue, the length of the sarcomere and also the proteolytic potential of the muscle. Post-mortem proteolysis by endogenous proteases causes the weakening of myofibril structures and associated proteins, which results in tenderisation. The caspase proteolytic system was first identified to be a potential contributor to post-mortem proteolysis and tenderisation in 2002. Since then research has both supported and challenged this hypothesis. The purpose of this review is to examine the experimental evidence available for caspases' involvement in post-mortem proteolysis, and to highlight cross-talk between this proteolytic system and the calpain system, a known contributor to meat tenderisation.
authors.affiliation: Central Community College, Grand Island, NE 68802, USA. carolinekemp@cccneb.edu
authors.forename: Caroline M
authors.initials: CM
authors.lastname: Kemp
authors.forename: Tim
authors.initials: T
authors.lastname: Parr
mesh_terms: D000818:Animals; D017209:Apoptosis; D002154:Calpain / Q000378:metabolism*; D020169:Caspases / Q000378:metabolism*; D004032:Diet; D005524:Food Technology; D006801:Humans; D008460:Meat; D009124:Muscle Proteins / Q000378:metabolism*; D009132:Muscles / Q000378:metabolism*; D009210:Myofibrils / Q000378:metabolism; D011180:Postmortem Changes; D059748:Proteolysis
chemical_list: D009124:Muscle Proteins; D002154:Calpain; D020169:Caspases