title: Dynamic visuomotor transformation involved with remote flying of a plane utilizes the 'Mirror Neuron' system.
abstract: Brain regions involved with processing dynamic visuomotor representational transformation are investigated using fMRI. The perceptual-motor task involved flying (or observing) a plane through a simulated Red Bull Air Race course in first person and third person chase perspective. The third person perspective is akin to remote operation of a vehicle. The ability for humans to remotely operate vehicles likely has its roots in neural processes related to imitation in which visuomotor transformation is necessary to interpret the action goals in an egocentric manner suitable for execution. In this experiment for 3(rd) person perspective the visuomotor transformation is dynamically changing in accordance to the orientation of the plane. It was predicted that 3(rd) person remote flying, over 1(st), would utilize brain regions composing the 'Mirror Neuron' system that is thought to be intimately involved with imitation for both execution and observation tasks. Consistent with this prediction differential brain activity was present for 3(rd) person over 1(st) person perspectives for both execution and observation tasks in left ventral premotor cortex, right dorsal premotor cortex, and inferior parietal lobule bilaterally (Mirror Neuron System) (Behaviorally: 1(st)>3(rd)). These regions additionally showed greater activity for flying (execution) over watching (observation) conditions. Even though visual and motor aspects of the tasks were controlled for, differential activity was also found in brain regions involved with tool use, motion perception, and body perspective including left cerebellum, temporo-occipital regions, lateral occipital cortex, medial temporal region, and extrastriate body area. This experiment successfully demonstrates that a complex perceptual motor real-world task can be utilized to investigate visuomotor processing. This approach (Aviation Cerebral Experimental Sciences ACES) focusing on direct application to lab and field is in contrast to standard methodology in which tasks and conditions are reduced to their simplest forms that are remote from daily life experience.
authors.affiliation: ATR Neural Information Analysis Laboratories, Kyoto, Japan. dcallan@atr.jp
authors.forename: Daniel E
authors.initials: DE
authors.lastname: Callan
authors.forename: Mario
authors.initials: M
authors.lastname: Gamez
authors.forename: Daniel B
authors.initials: DB
authors.lastname: Cassel
authors.forename: Cengiz
authors.initials: C
authors.lastname: Terzibas
authors.forename: Akiko
authors.initials: A
authors.lastname: Callan
authors.forename: Mitsuo
authors.initials: M
authors.lastname: Kawato
authors.forename: Masa-aki
authors.initials: MA
authors.lastname: Sato
mesh_terms: D000328:Adult; D000401:Aircraft; D001931:Brain Mapping; D002531:Cerebellum / Q000502:physiology; D003198:Computer Simulation; D005260:Female; D005625:Frontal Lobe / Q000502:physiology; D006179:Gyrus Cinguli / Q000502:physiology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D059167:Mirror Neurons / Q000502:physiology*; D009778:Occipital Lobe / Q000502:physiology; D010296:Parietal Lobe / Q000502:physiology; D011597:Psychomotor Performance; D013702:Temporal Lobe / Q000502:physiology; D013788:Thalamus / Q000502:physiology; D055815:Young Adult