title: Utilizing pharmacodynamic properties of second-generation antipsychotics to guide treatment.
abstract: Second-generation antipsychotics (SGAs) are used for the treatment of multiple psychiatric disorders including schizophrenia, bipolar depression, bipolar mania, autism and major depressive disorder. Additionally, their off-label use has been expanding to include other disorders as well, including post-traumatic stress disorder, obsessive compulsive disorder, generalized anxiety disorder, eating disorders and personality disorders. All SGAs share common properties; however, each individual SGA has a unique pharmacodynamic profile that may be utilized to guide and individualize treatment.
authors.affiliation: SUNY Upstate Medical University, Psychiatry Department, Syracuse, New York 13210, USA. SchwartT@upstate.edu
authors.forename: T
authors.initials: T
authors.lastname: Schwartz
authors.forename: K
authors.initials: K
authors.lastname: Bedynerman
mesh_terms: D014150:Antipsychotic Agents / Q000009:adverse effects / Q000627:therapeutic use*; D004348:Drug Labeling; D006801:Humans; D001523:Mental Disorders / Q000188:drug therapy*; D056687:Off-Label Use; D018579:Patient Selection; D016896:Treatment Outcome
chemical_list: D014150:Antipsychotic Agents