title: Massive spontaneous diaphragmatic rupture in Ehlers-Danlos syndrome.
abstract: Ehlers-Danlos syndrome (EDS) is a rare disorder caused by abnormalities in the synthesis and structure of collagen. The resultant tissue fragility and weakness can lead to multiple surgical conditions. In this report we present the very rare and life threatening case of a massive  spontaneous diaphragmatic rupture in a 35-year-old man with EDS and reflect on the literature, highlighting points to consider when managing such complex patients.
authors.affiliation: Department of Renal and Transplant Medicine, Hammersmith Campus, Imperial College London, London, UK. khamaoui@doctors.org.uk
authors.forename: K
authors.initials: K
authors.lastname: Hamaoui
authors.forename: A
authors.initials: A
authors.lastname: Riaz
authors.forename: A
authors.initials: A
authors.lastname: Hay
authors.forename: A
authors.initials: A
authors.lastname: Botha
mesh_terms: D000328:Adult; D003964:Diaphragm / Q000000981:diagnostic imaging / Q000601:surgery*; D004535:Ehlers-Danlos Syndrome / Q000150:complications*; D006801:Humans; D008297:Male; D009135:Muscular Diseases / Q000000981:diagnostic imaging / Q000209:etiology* / Q000601:surgery; D012422:Rupture, Spontaneous / Q000000981:diagnostic imaging / Q000209:etiology / Q000601:surgery; D014057:Tomography, X-Ray Computed