title: How an aspirin, a throat swab from a chicken, and four Guinea pigs changed thoracic surgery.
abstract: The development of antituberculous drugs changed thoracic surgery and also markedly lowered the morbidity and mortality of a disease that had epidemic proportions. This article summarizes aspects from 3 important articles that led to the discovery of these drugs.
authors.affiliation: Division of Cardiovascular and Thoracic Surgery, Mayo Clinic, Jacksonville, Florida 32224, USA. odell.john@mayo.edu
authors.forename: John A
authors.initials: JA
authors.lastname: Odell
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000266:history / Q000494:pharmacology; D000995:Antitubercular Agents / Q000266:history / Q000494:pharmacology*; D001241:Aspirin / Q000266:history / Q000494:pharmacology*; D002645:Chickens; D015195:Drug Design; D006168:Guinea Pigs; D049673:History, 20th Century; D006801:Humans; D010614:Pharynx / Q000382:microbiology*; D019616:Thoracic Surgical Procedures / Q000266:history*
chemical_list: D000900:Anti-Bacterial Agents; D000995:Antitubercular Agents; D001241:Aspirin