title: Absolute configuration for 1,n-glycols: a nonempirical approach to long-range stereochemical determination.
abstract: The absolute configurations of 1,n-glycols (n = 2-12, 16) bearing two chiral centers were rapidly determined via exciton-coupled circular dichroism (ECCD) using a tris(pentafluorophenyl)porphyrin (TPFP porphyrin) tweezer system in a nonempirical fashion devoid of chemical derivatization. A unique "side-on" approach of the porphyrin tweezer relative to the diol guest molecule is suggested as the mode of complexation.
authors.affiliation: Department of Chemistry, Michigan State University, East Lansing, 48824, United States.
authors.forename: Xiaoyong
authors.initials: X
authors.lastname: Li
authors.forename: Carmin E
authors.initials: CE
authors.lastname: Burrell
authors.forename: Richard J
authors.initials: RJ
authors.lastname: Staples
authors.forename: Babak
authors.initials: B
authors.lastname: Borhan
mesh_terms: D002942:Circular Dichroism; D018360:Crystallography, X-Ray; D006018:Glycols / Q000737:chemistry*; D008958:Models, Molecular; D009942:Organometallic Compounds / Q000737:chemistry; D011166:Porphyrins / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D006018:Glycols; D009942:Organometallic Compounds; D011166:Porphyrins