title: Leukoreduction in patients with severe pertussis with hyperleukocytosis.
abstract: When pertussis is associated with hyperleukocytosis, mortality approaches to 80%. Immature leukocytes have been identified in pulmonary arterioles, small arteries and venules. Techniques aimed at reducing leukocyte mass might improve the prognosis of these patients. We report our experience with 3 patients in whom a leukoreduction was performed in the context of severe pertussis and hyperleukocytosis.
authors.affiliation: Pediatric Intensive Care Unit, Hospital Infantil Universitario Niño Jesús, Madrid, Spain. gonorootero@hotmail.com
authors.forename: Gonzalo
authors.initials: G
authors.lastname: Oñoro
authors.forename: Alberto García
authors.initials: AG
authors.lastname: Salido
authors.forename: Ignacio Mastro
authors.initials: IM
authors.lastname: Martínez
authors.forename: Beatriz
authors.initials: B
authors.lastname: Cabeza
authors.forename: María
authors.initials: M
authors.lastname: Gillén
authors.forename: Amelia Martínez
authors.initials: AM
authors.lastname: de Azagra
mesh_terms: D005078:Exchange Transfusion, Whole Blood; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D000860:Hypoxia / Q000097:blood; D007223:Infant; D015278:Intensive Care Units, Pediatric; D007937:Leukapheresis; D007964:Leukocytosis / Q000097:blood* / Q000628:therapy*; D008297:Male; D014917:Whooping Cough / Q000097:blood* / Q000628:therapy*