title: Cellulitis with leukocytopenia as an initial sign of acute promyelocytic leukemia.
abstract: Patients with hematologic malignancies are immunosuppressive and may develop cutaneous or invasive infections as a primary sign of immune suppression. Acute promyelocytic leukemia (acute myeloid leukemia M3) is caused by translocation of reciprocal chromosomal rearrangement t(15;17), which produces an oncogenic protein. We herein describe a 71-year-old man having cellulitis with leukocytopenia as a first sign of acute promyelocytic leukemia. Dermatologists and hematologists should keep in mind that patients with a hematologic malignancy, such as acute promyelocytic leukemia, can develop cellulitis with leukocytopenia.
authors.affiliation: Department of Dermatology, Kinki University Faculty of Medicine, Osaka-Sayama, Japan.
authors.forename: Sachiko
authors.initials: S
authors.lastname: Sakamoto
authors.forename: Naoki
authors.initials: N
authors.lastname: Oiso
authors.forename: Masakatsu
authors.initials: M
authors.lastname: Emoto
authors.forename: Shusuke
authors.initials: S
authors.lastname: Uchida
authors.forename: Ayaka
authors.initials: A
authors.lastname: Hirao
authors.forename: Yoichi
authors.initials: Y
authors.lastname: Tatsumi
authors.forename: Itaru
authors.initials: I
authors.lastname: Matsumura
authors.forename: Akira
authors.initials: A
authors.lastname: Kawada