title: Pushing the limit: synthesis, photophysical and DNA binding studies of a NIR-emitting Ru(II)-polypyridyl probe with 'light switch' behaviour.
abstract: The new Ru(II) polypyridyl complex 1 was synthesised using microwave irradiation from the new polypyridyl ligand 2'DipyTAP', and its photophysical properties, and DNA binding abilities were investigated using various spectroscopic techniques; and 1 was shown to act as a 'NIR molecular light switch' for DNA with an emission window between 680 and 860 nm.
authors.affiliation: School of Chemistry, Centre for Synthesis and Chemical Biology, Trinity College Dublin, Dublin 2, Ireland. elmesr@tcd.ie
authors.forename: Robert B P
authors.initials: RB
authors.lastname: Elmes
authors.forename: Jonathan A
authors.initials: JA
authors.lastname: Kitchen
authors.forename: D Clive
authors.initials: DC
authors.lastname: Williams
authors.forename: Thorfinnur
authors.initials: T
authors.lastname: Gunnlaugsson
mesh_terms: D000818:Animals; D060326:Chemistry Techniques, Synthetic; D004247:DNA / Q000737:chemistry* / Q000378:metabolism; D008027:Light; D008958:Models, Molecular; D008968:Molecular Conformation; D009942:Organometallic Compounds / Q000138:chemical synthesis* / Q000737:chemistry* / Q000378:metabolism; D011725:Pyridines / Q000737:chemistry* / Q000378:metabolism; D012428:Ruthenium / Q000737:chemistry* / Q000378:metabolism; D013055:Spectrophotometry, Infrared
chemical_list: D009942:Organometallic Compounds; D011725:Pyridines; D012428:Ruthenium; D004247:DNA