title: Pneumocystis jirovecii pneumonia 13 years post renal transplant following a recurrent cytomegalovirus infection.
abstract: Pneumocystis jirovecii (formerly Pneumocystis carinii) pneumonia (PCP) is a rare but serious infection that usually occurs within a year after solid organ transplantation. PCP may occur after 1 year post transplantation, but the rate is reported to be very low. Studies have shown an association between cytomegalovirus (CMV) infection in solid organ transplant patients and an increased risk of opportunistic infection. This increased risk is thought to be a result of the immunomodulatory effects of the CMV infection. We present a case of PCP infection occurring 13 years after a renal transplantation. This occurred following a recurrent CMV infection while the patient was on low-dose immunosuppressants.
authors.affiliation: Department of Medicine, Universiti Teknologi MARA, Selangor, Malaysia. fmeu6038@yahoo.co.uk
authors.forename: A H
authors.initials: AH
authors.lastname: Muhammad Iqbal
authors.forename: S K
authors.initials: SK
authors.lastname: Lim
authors.forename: K P
authors.initials: KP
authors.lastname: Ng
authors.forename: L P
authors.initials: LP
authors.lastname: Tan
authors.forename: Y B
authors.initials: YB
authors.lastname: Chong
authors.forename: T C
authors.initials: TC
authors.lastname: Keng
mesh_terms: D000328:Adult; D003587:Cytomegalovirus; D003586:Cytomegalovirus Infections / Q000276:immunology* / Q000821:virology; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage; D016030:Kidney Transplantation / Q000009:adverse effects*; D009894:Opportunistic Infections / Q000276:immunology* / Q000382:microbiology; D045363:Pneumocystis carinii; D011020:Pneumonia, Pneumocystis / Q000276:immunology* / Q000382:microbiology*; D012008:Recurrence; D012307:Risk Factors; D013997:Time Factors
chemical_list: D007166:Immunosuppressive Agents