title: [Genetic causes of infantile spasms--a systematic review].
abstract: Infantile spasms are a symptom of a severe epileptic encephalopathy. It is important to determine the aetiology for a child's disease. When a standard programme for evaluating the aetiology of the infantile spasms is unsuccessful genetic causes should be considered. We suggest array CGH as the first-line analysis and present an overview of relevant present possibilities for genetic testing.
authors.affiliation: HC Andersen Børnehospital, Odense Universitetshospital, Sdr. Boulevard 29, 5000 Odense, Denmark. lars.kjaersgaard@dadlnet.dk
authors.forename: Lars Kjærsgaard
authors.initials: LK
authors.lastname: Hansen
authors.forename: Lilian Bomme
authors.initials: LB
authors.lastname: Ousager
authors.forename: Rikke Steensbjerre
authors.initials: RS
authors.lastname: Møller
authors.forename: Peter V
authors.initials: PV
authors.lastname: Uldall
authors.forename: Helle
authors.initials: H
authors.lastname: Hjalgrim
mesh_terms: D002869:Chromosome Aberrations; D055028:Comparative Genomic Hybridization; D003937:Diagnosis, Differential; D004827:Epilepsy / Q000175:diagnosis / Q000235:genetics; D005820:Genetic Testing; D006801:Humans; D007223:Infant; D013036:Spasms, Infantile / Q000175:diagnosis / Q000209:etiology / Q000235:genetics*