title: Synthesis of phenothiazines via ligand-free CuI-catalyzed cascade C-S and C-N coupling of aryl ortho-dihalides and ortho-aminobenzenethiols.
abstract: A ligand-free CuI-catalyzed cascade C-S and C-N cross coupling of (hetero)aryl ortho-dihalides and ortho-aminobenzenethiols has been developed, and various phenothiazines were synthesized with excellent regioselectivity. A possible mechanism is proposed for the cascade coupling.
authors.affiliation: Institute of Green Catalysis and Synthesis, College of Materials and Chemistry & Chemical Engineering, Chengdu University of Technology, Chengdu 610059, China.
authors.forename: Chuan
authors.initials: C
authors.lastname: Dai
authors.forename: Xiaofei
authors.initials: X
authors.lastname: Sun
authors.forename: Xingzhao
authors.initials: X
authors.lastname: Tu
authors.forename: Li
authors.initials: L
authors.lastname: Wu
authors.forename: Dan
authors.initials: D
authors.lastname: Zhan
authors.forename: Qingle
authors.initials: Q
authors.lastname: Zeng
mesh_terms: D002244:Carbon / Q000737:chemistry; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D007454:Iodides / Q000737:chemistry*; D008024:Ligands; D009584:Nitrogen / Q000737:chemistry; D010636:Phenols / Q000737:chemistry*; D010640:Phenothiazines / Q000138:chemical synthesis / Q000737:chemistry*; D013237:Stereoisomerism; D013438:Sulfhydryl Compounds / Q000737:chemistry*; D013455:Sulfur / Q000737:chemistry
chemical_list: D007454:Iodides; D008024:Ligands; D010636:Phenols; D010640:Phenothiazines; D013438:Sulfhydryl Compounds; D013455:Sulfur; D002244:Carbon; D003300:Copper; C073870:cuprous iodide; C042983:thiophenol; D009584:Nitrogen