title: Synthesis of monodisperse, hierarchically mesoporous, silica microspheres embedded with magnetic nanoparticles.
abstract: We report a preparation method for the synthesis of monodisperse magnetic polymer/silica hybrid microspheres using polymer microspheres incorporated with magnetic nanoparticles as a novel template. Monodisperse, hierarchically mesoporous, silica microspheres embedded with magnetic nanoparticles were successfully fabricated after the calcination of the hybrid microspheres. The magnetic nanoparticles were encapsulated in silica and distributed over the whole area of the porous microspheres without leakage. The resulting inorganic materials possess highly useful properties such as high magnetic nanoparticle loading, high surface area, and large pore volumes. The hierarchically mesoporous magnetic silica microspheres resulted in a high bovine serum albumin (BSA) protein adsorption capacity (260 mg/g) and a fast adsorption rate (reaching equilibrium with 8 h).
authors.affiliation: Nano-Micro Materials Research Center, School of Chemical Biology & Biotechnology, Peking University Shenzhen Graduate School, Shenzhen 518055, China.
authors.forename: Yong
authors.initials: Y
authors.lastname: Wang
authors.forename: Jie
authors.initials: J
authors.lastname: He
authors.forename: Jiwei
authors.initials: J
authors.lastname: Chen
authors.forename: Lianbing
authors.initials: L
authors.lastname: Ren
authors.forename: Biwang
authors.initials: B
authors.lastname: Jiang
authors.forename: Jing
authors.initials: J
authors.lastname: Zhao
mesh_terms: D000327:Adsorption; D000818:Animals; D002417:Cattle; D058185:Magnetite Nanoparticles / Q000737:chemistry*; D008863:Microspheres; D016062:Porosity; D012710:Serum Albumin, Bovine / Q000737:chemistry*; D012822:Silicon Dioxide / Q000737:chemistry*
chemical_list: D058185:Magnetite Nanoparticles; D012710:Serum Albumin, Bovine; D012822:Silicon Dioxide