title: High resolution impedance manometric findings in dysphagia of Huntington's disease.
abstract: Conventional manometry presents significant challenges, especially in assessment of pharyngeal swallowing, because of the asymmetry and deglutitive movements of oropharyngeal structures. It only provides information about intraluminal pressure and thus it is difficult to study functional details of esophageal motility disorders. New technology of solid high resolution impedance manometry (HRIM), with 32 pressure sensors and 6 impedance sensors, is likely to provide better assessment of pharyngeal swallowing as well as more information about esophageal motility disorders. However, the clinical usefulness of application of HRIM in patients with oropharyngeal dysphagia or esophageal dysphagia is not known. We experienced a case of Huntington's disease presenting with both oropharyngeal and esophageal dysphagia, in which HRIM revealed the mechanism of oropharyngeal dysphagia and provided comprehensive information about esophageal dysphagia.
authors.affiliation: Institute for Digestive Research, Soon Chun Hyang College of Medicine, Seoul 140-743, South Korea.
authors.forename: Tae Hee
authors.initials: TH
authors.lastname: Lee
authors.forename: Joon Seong
authors.initials: JS
authors.lastname: Lee
authors.forename: Wan Jung
authors.initials: WJ
authors.lastname: Kim
mesh_terms: D000368:Aged; D003680:Deglutition Disorders / Q000150:complications* / Q000175:diagnosis*; D017097:Electric Impedance; D015154:Esophageal Motility Disorders / Q000150:complications* / Q000175:diagnosis*; D004947:Esophagus / Q000503:physiopathology; D006801:Humans; D006816:Huntington Disease / Q000150:complications*; D008297:Male; D008365:Manometry / Q000379:methods*; D009960:Oropharynx / Q000503:physiopathology