title: Cushing disease with pregnancy.
abstract: Pregnancy occurs rarely in patients with Cushing syndrome (CS) due to hypercortisolism. So far, about 150 cases of CS in pregnancy have been reported in the literature. We describe a 22-year-old female who presented in pregnancy with clinical features of CS. She delivered at 34 weeks of gestation and baby had transient adrenal insufficiency in the neonatal period. Mother underwent transsphenoidal surgery 1 year postpartum and on follow up she is under remission. Neonatal hypoadrenalism should be anticipated in maternal CS.
authors.affiliation: Department of Endocrinology, KEM Hospital, Mumbai, India. drrajugopal@gmail.com
authors.forename: Raju A
authors.initials: RA
authors.lastname: Gopal
authors.forename: Shrikrishna V
authors.initials: SV
authors.lastname: Acharya
authors.forename: Tushar R
authors.initials: TR
authors.lastname: Bandgar
authors.forename: Padma S
authors.initials: PS
authors.lastname: Menon
authors.forename: Nalini S
authors.initials: NS
authors.lastname: Shah
mesh_terms: D049913:ACTH-Secreting Pituitary Adenoma / Q000503:physiopathology / Q000601:surgery; D000236:Adenoma / Q000503:physiopathology / Q000601:surgery; D000309:Adrenal Insufficiency / Q000151:congenital / Q000188:drug therapy / Q000209:etiology; D000328:Adult; D003480:Cushing Syndrome / Q000175:diagnosis* / Q000209:etiology / Q000503:physiopathology* / Q000628:therapy; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000627:therapeutic use; D007231:Infant, Newborn; D007234:Infant, Premature; D007235:Infant, Premature, Diseases / Q000188:drug therapy / Q000209:etiology; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis* / Q000209:etiology / Q000503:physiopathology* / Q000628:therapy; D047928:Premature Birth / Q000209:etiology; D012127:Respiratory Distress Syndrome, Newborn / Q000209:etiology / Q000628:therapy; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D006854:Hydrocortisone