title: Short and long terms healing of the experimentally transverse sectioned tendon in rabbits.
abstract: BACKGROUND
  The incidences of tendon injuries in certain sections of human or animal populations such as athletes are high, but every human or animal, regardless of age or level of activity experiences some degree of tendon injury. In spite of the various investigations of injuries and treatment, comprehensive studies dealing with the histological, ultrastructural and biomechanical aspects of healing of load-bearing tendons are rare. This study was designed to compare the outcome of healing of the transverse sectioned superficial digital flexor tendon (SDFT) after 28 and 84 days post injury (DPI) in rabbits.
  
  
  METHODS
  Forty white New Zealand mature female rabbits were randomly divided into two equal groups of 28 and 84 DPI After tenotomy and surgical repair of the left SDFT, the injured legs were casted for 14 days. The weight of the animals, tendon diameter, and clinical, radiographic and ultrasonographic evaluations were conducted at weekly intervals. The animals were euthanized on 28 and 84 DPI and the tendons were evaluated for histopathological, ultrastructural, biomechanical and percentage dry weight parameters.
  
  
  RESULTS
  Although the clinical, ultrastructural, morphological and biomechanical properties of the injured tendons on day 84 showed a significant improvement compared to those of the 28 DPI, these parameters were still significantly inferior to their normal contra-lateral tendons.
  
  
  CONCLUSIONS
  This study showed that tendon healing is very slow and at 84 days post-injury the morphological and biomechanical parameters were still inferior to the normal tendons and many collagen fibrils still had the same diameter as those seen at 28 DPI.
authors.affiliation: Department of Surgery and Radiology, Group of Clinical Studies, School of Veterinary Medicine, Shiraz University, Shiraz, Iran. dr.ali.moshiri@gmail.com.
authors.forename: Ahmad
authors.initials: A
authors.lastname: Oryan
authors.forename: Ali
authors.initials: A
authors.lastname: Moshiri
authors.forename: Abdul-Hamid
authors.initials: AH
authors.lastname: Meimandi-Parizi