title: Tachyon search speeds up retrieval of similar sequences by several orders of magnitude.
abstract: The usage of current sequence search tools becomes increasingly slower as databases of protein sequences continue to grow exponentially. Tachyon, a new algorithm that identifies closely related protein sequences ~200 times faster than standard BLAST, circumvents this limitation with a reduced database and oligopeptide matching heuristic.
  
  
  METHODS
  The tool is publicly accessible as a webserver at http://tachyon.bii.a-star.edu.sg and can also be accessed programmatically through SOAP.
authors.affiliation: Bioinformatics Institute (BII), Agency for Science Technology and Research (A*STAR), 30 Biopolis Street, #07-01, Matrix, 138671, Singapore.
authors.forename: Joshua
authors.initials: J
authors.lastname: Tan
authors.forename: Durga
authors.initials: D
authors.lastname: Kuchibhatla
authors.forename: Fernanda L
authors.initials: FL
authors.lastname: Sirota
authors.forename: Westley A
authors.initials: WA
authors.lastname: Sherman
authors.forename: Tobias
authors.initials: T
authors.lastname: Gattermayer
authors.forename: Chia Yee
authors.initials: CY
authors.lastname: Kwoh
authors.forename: Frank
authors.initials: F
authors.lastname: Eisenhaber
authors.forename: Georg
authors.initials: G
authors.lastname: Schneider
authors.forename: Sebastian
authors.initials: S
authors.lastname: Maurer-Stroh
mesh_terms: D000465:Algorithms; D000595:Amino Acid Sequence; D030562:Databases, Protein; D006801:Humans; D020407:Internet; D057386:Search Engine