title: Comparison of the severity and outcome of invasive pneumococcal infections in children and adults.
abstract: In a population-based observational study of 285 patients with positive blood culture for pneumococci, we found that the course and outcome of invasive pneumococcal infections differ considerably between adults and children. None of the children died, whereas the infection was fatal for 15% (35/229) of the adults (P<0.001). The differences are only partly explained by the underlying conditions.
authors.affiliation: Department of Pediatrics, University of Oulu, and Department of Internal Medicine, Oulu University Hospital, Oulu, Finland. marjo.renko@oulu.fi
authors.forename: Marjo
authors.initials: M
authors.lastname: Renko
authors.forename: Hanna-Leena
authors.initials: HL
authors.lastname: Kukkola
authors.forename: Heikki
authors.initials: H
authors.lastname: Kauma
authors.forename: Terhi
authors.initials: T
authors.lastname: Tapiainen
authors.forename: Tarja
authors.initials: T
authors.lastname: Kaijalainen
authors.forename: Matti
authors.initials: M
authors.lastname: Uhari
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D016470:Bacteremia / Q000401:mortality* / Q000473:pathology*; D002648:Child; D003422:Critical Care / Q000706:statistics & numerical data; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007902:Length of Stay / Q000706:statistics & numerical data; D008297:Male; D008875:Middle Aged; D011008:Pneumococcal Infections / Q000401:mortality* / Q000473:pathology*; D011247:Pregnancy; D016019:Survival Analysis; D055815:Young Adult