title: [The characteristics of metabolism in patients with fractures of shin and thigh bones depending on immobilization period].
abstract: The comprehensive biochemical examination of 20 patients with fractures of shin and thigh bones aged from 18 to 50 years was organized. The treatment consisted of skeletal traction meaning a lingering limitation of locomotive activity The blood sampled at 7th, 14th, 21th, 28th and 35th days after trauma. The blood plasma was analyzed to establish the indicators of protein and purine metabolism, lipoperoxidation processes and antiradical activity. The study established the catabolic direction of metabolism and the intensification of lipoperoxidation processes of the background of decreasing of antiradical activity. The research data can be recommended to apply in controlling the impact of forced limitation of locomotive activity on the course of post-trauma process.
authors.forename: A V
authors.initials: AV
authors.lastname: Elikov
authors.forename: S A
authors.initials: SA
authors.lastname: Karavaev
authors.forename: P I
authors.initials: PI
authors.lastname: Tsapok
mesh_terms: D000293:Adolescent; D000328:Adult; D000975:Antioxidants / Q000378:metabolism*; D001510:Bed Rest; D001798:Blood Proteins / Q000378:metabolism*; D005264:Femoral Fractures / Q000097:blood* / Q000628:therapy; D005592:Fracture Fixation; D006801:Humans; D015227:Lipid Peroxidation; D008297:Male; D011687:Purines / Q000097:blood*; D013978:Tibial Fractures / Q000097:blood* / Q000628:therapy; D013997:Time Factors
chemical_list: D000975:Antioxidants; D001798:Blood Proteins; D011687:Purines