title: Does augmentation with a reinforced fascia patch improve rotator cuff repair outcomes?
abstract: BACKGROUND
  Scaffold devices are used to augment rotator cuff repairs in humans. While the strength of a novel poly-L-lactic acid-reinforced (human) fascia patch has been documented, it is unclear whether such patches will enhance the strength or likelihood of healing of rotator cuff repairs.
  
  
  OBJECTIVE
  In a canine shoulder model, we asked: Do tendon repairs augmented with a reinforced fascia patch have (1) increased biomechanical properties at Time 0 and (2) less tendon retraction and increased cross-sectional area and biomechanical properties after 12 weeks of healing compared to repairs without augmentation? (3) Do the biomechanical properties of tendon repairs reach normal values by 12 weeks of healing? And (4) is the host response associated with use of the reinforced fascia patch biocompatible?
  
  
  METHODS
  Eleven dogs underwent bilateral shoulder surgery with partial release and acute repair of the infraspinatus tendon, one shoulder with augmentation and one without augmentation. Repair retraction, cross-sectional area, biomechanical properties, and biocompatibility were assessed at 12 weeks.
  
  
  RESULTS
  At Time 0, the mean ± SD ultimate load of augmented repairs was 296 ± 130 N (46% ± 25%) more than nonaugmented repairs, with no difference in stiffness between groups. At 12 weeks, the ultimate load of augmented repairs averaged 192 ± 213 N (15% ± 16%) less than nonaugmented repairs, with no difference in stiffness between groups. At the tendon repair site at 12 weeks, the fascia patch showed a biocompatible host tissue response.
  
  
  CONCLUSIONS
  The biomechanical properties of repairs augmented with a reinforced fascia patch demonstrated greater ultimate load at Time 0 than nonaugmented repairs but remained essentially unchanged after 12 weeks of healing, despite improvements in the ultimate load of nonaugmented controls in the same time frame.
authors.affiliation: Department of Biomedical Engineering, Orthopaedic and Rheumatologic Research Center, Cleveland Clinic Foundation, Cleveland, OH, USA.
authors.forename: Andrew R
authors.initials: AR
authors.lastname: Baker
authors.forename: Jesse A
authors.initials: JA
authors.lastname: McCarron
authors.forename: Carmela D
authors.initials: CD
authors.lastname: Tan
authors.forename: Joseph P
authors.initials: JP
authors.lastname: Iannotti
authors.forename: Kathleen A
authors.initials: KA
authors.lastname: Derwin
mesh_terms: D000818:Animals; D001672:Biocompatible Materials; D001696:Biomechanical Phenomena; D004285:Dogs; D004548:Elasticity; D005205:Fascia / Q000637:transplantation*; D006801:Humans; D019344:Lactic Acid / Q000737:chemistry*; D008297:Male; D023421:Models, Animal; D019637:Orthopedic Procedures; D011091:Polyesters; D011108:Polymers / Q000737:chemistry*; D020127:Recovery of Function; D017006:Rotator Cuff / Q000473:pathology / Q000503:physiopathology / Q000601:surgery*; D013997:Time Factors; D054457:Tissue Scaffolds; D016474:Weight-Bearing; D014945:Wound Healing
chemical_list: D001672:Biocompatible Materials; D011091:Polyesters; D011108:Polymers; D019344:Lactic Acid; C033616:poly(lactide)