title: [Navigated focal retinal laser therapy using the NAVILAS® system for diabetic macula edema].
abstract: OBJECTIVE
  The aim of this study was to investigate the accuracy of a navigated laser photocoagulator in clinically significant macular edema (CSME).
  
  
  METHODS
  Focal laser treatment for diabetic macular edema (DME) in 36 patients was digitally planned on fundus images and performed with navigation using NAVILAS® (OD-OS, Teltow, Germany). Treatment intensity was controlled visually during treatment so the laser spots applied were barely directly visible after treatment. Using color images (CI) and optical coherence tomography (OCT) 4,137 laser spots (mean 115 per eye) were analyzed at 1 month follow-up and accuracy of spot placement was determined.
  
  
  RESULTS
  In total 79% of laser spots were visible on CI of which 96% were within 100 µm of the planned target position. On an intention-to-treat (ITT) basis, 76% of the laser spots were placed and visible within the 100 µm target and OCT confirmed that laser effects were limited to the outer retina. The mean time for focal treatment was < 7 min (±3 min).
  
  
  CONCLUSIONS
  After NAVILAS treatment for DME a high percentage of laser effects could be visualized on post-treatment color images and the location showed high concordance with the preplanning target.
authors.affiliation: Augenklinik der Ludwig-Maximilians-Universität, Mathildenstr. 8, 80336, München, Deutschland. Marcus.Kernt@med.uni-muenchen.de
authors.forename: M
authors.initials: M
authors.lastname: Kernt
authors.forename: R
authors.initials: R
authors.lastname: Cheuteu
authors.forename: R G
authors.initials: RG
authors.lastname: Liegl
authors.forename: F
authors.initials: F
authors.lastname: Seidensticker
authors.forename: S
authors.initials: S
authors.lastname: Cserhati
authors.forename: C
authors.initials: C
authors.lastname: Hirneiss
authors.forename: C
authors.initials: C
authors.lastname: Haritoglou
authors.forename: A
authors.initials: A
authors.lastname: Kampik
authors.forename: M
authors.initials: M
authors.lastname: Ulbig
authors.forename: A S
authors.initials: AS
authors.lastname: Neubauer
mesh_terms: D003930:Diabetic Retinopathy / Q000150:complications / Q000175:diagnosis* / Q000601:surgery*; D004867:Equipment Design; D019544:Equipment Failure Analysis; D005260:Female; D006801:Humans; D017075:Laser Coagulation / Q000295:instrumentation* / Q000379:methods*; D008269:Macular Edema / Q000175:diagnosis* / Q000209:etiology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome