title: Chiral nanoporous metal-metallosalen frameworks for hydrolytic kinetic resolution of epoxides.
abstract: Chiral nanoporous metal-organic frameworks are constructed by using dicarboxyl-functionalized chiral Ni(salen) and Co(salen) ligands. The Co(salen)-based framework is shown to be an efficient and recyclable heterogeneous catalyst for hydrolytic kinetic resolution (HKR) of racemic epoxides with up to 99.5% ee. The MOF structure brings Co(salen) units into a highly dense arrangement and close proximity that enhances bimetallic cooperative interactions, leading to improved catalytic activity and enantioselectivity in HKR compared with its homogeneous analogues, especially at low catalyst/substrate ratios.
authors.affiliation: School of Chemistry and Chemical Technology and State Key Laboratory of Metal Matrix Composites, Shanghai Jiao Tong University, Shanghai 200240, China.
authors.forename: Chengfeng
authors.initials: C
authors.lastname: Zhu
authors.forename: Guozan
authors.initials: G
authors.lastname: Yuan
authors.forename: Xu
authors.initials: X
authors.lastname: Chen
authors.forename: Zhiwei
authors.initials: Z
authors.lastname: Yang
authors.forename: Yong
authors.initials: Y
authors.lastname: Cui