title: Fanconi anemia and vaginal squamous cell carcinoma.
abstract: Fanconi Anemia (FA) is an autosomal recessive disease characterized by chromosome instability, cellular hypersensitivity to DNA cross-linking agents, and increased predisposition to malignancies. We describe here a 28 year-old female with FA and vaginal squamous cell carcinoma treated by radiation therapy alone. The patient developed arm phlebitis, pulmonary fungal infection, and severe rectal bleeding, followed by hypocalcaemia, hypokalemia, vaginal bacterial and fungal infection, with subsequent leg and arm phlebitis, perineal abscess, and sepsis. The patient died 12 weeks later.
authors.affiliation: Department of Obstetrics and Gynecology.
authors.forename: Altamiro Ribeiro
authors.initials: AR
authors.lastname: Dias
authors.forename: Marcela Cavalcante
authors.initials: MC
authors.lastname: de Andrade Silva
authors.forename: Filomena Marino
authors.initials: FM
authors.lastname: Carvalho
authors.forename: Heloisa
authors.initials: H
authors.lastname: de Andrade Carvalho
authors.forename: Maria Del Pilar
authors.initials: Mdel P
authors.lastname: Esteves Diz
authors.forename: Edmund Chada
authors.initials: EC
authors.lastname: Baracat
authors.forename: Jesus Paula
authors.initials: JP
authors.lastname: Carvalho