title: Design of nanoporous metals with bimodal pore size distributions for enhanced biosensing.
abstract: Nanoporous gold (np-Au) has shown great potential in catalysis, plasmonics, sensing, etc. In this work, by two-step dealloying a well-designed AuAgAl ternary precursor alloy, np-Au with bimodal ligament/pore size distributions is successfully fabricated. The first dealloying in HCl solution removes Al and generates a nanoporous AuAg alloy which would be mildly annealed at 200 °C for 30 min to homogenize the alloy ligament and enlarge the ligament/pore size. Next, the nanoporous AuAg alloy is further dealloyed in a HNO(3) solution to etch Ag and fabricate np-Au with a hierarchical microstructure. This novel bimodal np-Au is demonstrated to exhibit enhanced electrocatalytic activity towards H(2)O(2) reduction and be a better support for the fabrication of an oxidase-based biosensor compared with normal np-Au, with a uniform pore/ligament size of 30-40 nm. In a proof-of-concept study, a sensitive glucose biosensor with a linear range up to 21 mM is fabricated by immobilization of glucose oxidase on the bimodal np-Au.
authors.affiliation: School of Chemistry and Chemical Engineering, Shandong University, Jinan 250100, China. qiuhuajun@gmail.com
authors.forename: Huajun
authors.initials: H
authors.lastname: Qiu
authors.forename: Xiaochen
authors.initials: X
authors.lastname: Dong
authors.forename: Xirong
authors.initials: X
authors.lastname: Huang