title: The first report of disseminated Nocardia concava infection, in an immunocompromised patient, in South Korea.
abstract: A new Nocardia species, N. concava, was first reported in Japan in 2005. To date, there have been only 3 case reports of N. concava infection worldwide (2 in Japan and 1 in China), and only 1 of these reports has detailed the clinical characteristics of N. concava, in China. Here we report the first case of disseminated infection caused by N. concava- in a patient with a history of glucocorticoid use-in South Korea. Species identification of N. concava was done with 16S rRNA sequencing and was confirmed by biochemical tests using urea, xanthine, tyrosine, and hypoxanthine decomposition. The patient was successfully treated with trimethoprim-sulfamethoxazole.
authors.affiliation: Department of Infectious Diseases, Asan Medical Center, University of Ulsan College of Medicine, 388-1 Poonganp dong, Songpa-gu, Seoul, 138-736, South Korea.
authors.forename: Seung-Hoon
authors.initials: SH
authors.lastname: Lee
authors.forename: Heungseop
authors.initials: H
authors.lastname: Sung
authors.forename: Sang-Oh
authors.initials: SO
authors.lastname: Lee
authors.forename: Sang-Ho
authors.initials: SH
authors.lastname: Choi
authors.forename: Yang-Soo
authors.initials: YS
authors.lastname: Kim
authors.forename: Jun-Hee
authors.initials: JH
authors.lastname: Woo
authors.forename: Sung-Han
authors.initials: SH
authors.lastname: Kim
mesh_terms: D000038:Abscess / Q000188:drug therapy / Q000276:immunology / Q000382:microbiology / Q000473:pathology; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001132:Arm / Q000382:microbiology / Q000473:pathology; D057645:Deltoid Muscle / Q000382:microbiology / Q000473:pathology; D006801:Humans; D016867:Immunocompromised Host; D008297:Male; D008875:Middle Aged; D009615:Nocardia; D009617:Nocardia Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology* / Q000382:microbiology; D056910:Republic of Korea; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000627:therapeutic use
chemical_list: D000900:Anti-Bacterial Agents; D015662:Trimethoprim, Sulfamethoxazole Drug Combination