title: [Exclusion of coronary artery disease using cardiac CT. What impact do CT results have on patient management?].
abstract: Rapid advancement of multidetector head computed tomography (MDCT) during the past 10 years has facilitated noninvasive evaluation of CAD (coronary artery disease). Since the introduction of 320-row technology, examination of the whole heart in a single heart beat with diagnostic quality has become feasible. Direct imaging of vessel morphology, a high sensitivity for CAD above 96%, and low requirements of patient compliance represent advantages over other imaging modalities, such as MRI (magnetic resonance imaging), scintigraphy, and echocardiography. In some cases radiation exposure can be reduced to an effective dose below 1 mSV.Current data suggest that cardiac CT represents a more effective diagnostic tool than treadmill testing in order to decide whether cardiac catheterization is indicated. Treadmill testing has been an integral procedure of cardiac examinations for decades, although sensitivity for detecting CAD is as low as 70%.Cardiac CT represents a rather new modality and is almost exclusively performed in diagnostic imaging centers. Innovative concepts in the evaluation of CAD including CT are expected. Some authors propose cardiac CT as a major diagnostic tool for the exclusion of CAD. MRI, scintigraphy, or echocardiography in combination with a stress test remain important procedures in order to evaluate the hemodynamic relevance of coronary artery stenosis. Treadmill testing prior to cardiac CT has become questionable.The future role of cardiac CT in CAD in "change of management" concepts is promising. In order to optimize decisions of patient management on the basis of a cardiac CT examinations, awareness of current data is mandatory for the referring clinician and the performing radiological department.
authors.affiliation: Praxisklinik Herz und Gefäße, Kardiologie, Angiologie, Radiologie, Nuklearmedizin - Akademische Lehrpraxisklinik der TU Dresden, Forststraße 3, Dresden, Germany. Dr.Kadalie@praxisklinik-dresden.de
authors.forename: Clemens Themba
authors.initials: CT
authors.lastname: Kadalie
authors.forename: Reinhardt
authors.initials: R
authors.lastname: Sternitzky
mesh_terms: D017023:Coronary Angiography / Q000379:methods*; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging* / Q000628:therapy; D006801:Humans; D061330:Multidetector Computed Tomography; D018579:Patient Selection; D011237:Predictive Value of Tests; D011379:Prognosis; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index