title: Intracranial sarcoid granuloma as an extension of severe sinonasal sarcoidosis.
abstract: Sarcoidosis is a chronic, multisystem, granulomatous disease of unknown etiology. It manifests with a wide range of symptoms and clinical findings, including some that occur in the head and neck. Sinonasal sarcoidosis, in particular, frequently demonstrates a rather recalcitrant course and a potential for severe complications if left untreated. We present the case of a 46-year-old woman with extensive sinonasal sarcoidosis that progressed to involve the skull base and olfactory tract and ultimately led to the formation of a granuloma within the frontal lobe that required craniotomy and excision. Although surgery is not considered the primary treatment modality for sarcoidosis, it may have a role in managing this highly variable disease in certain patients.
authors.affiliation: Alpine Ear, Nose & Throat, Fort Collins, CO 80524, USA. Smwold1@yahoo.com
authors.forename: Stephen M
authors.initials: SM
authors.lastname: Wold
authors.forename: John T
authors.initials: JT
authors.lastname: Sinacori
mesh_terms: D001932:Brain Neoplasms / Q000188:drug therapy / Q000209:etiology* / Q000601:surgery; D005260:Female; D005682:Gadolinium; D006099:Granuloma / Q000188:drug therapy / Q000209:etiology* / Q000601:surgery; D006801:Humans; D008875:Middle Aged; D000857:Olfaction Disorders; D012507:Sarcoidosis / Q000150:complications* / Q000188:drug therapy / Q000601:surgery
chemical_list: D005682:Gadolinium