title: Impact of COPD exacerbation on cerebral blood flow.
abstract: We aimed to investigate the impact of chronic obstructive pulmonary disease (COPD) exacerbation on cerebral blood flow (CBF). In 21 COPD patients - in both exacerbation and stable phases -Doppler ultrasonographies of internal carotid artery (ICA) and vertebral artery (VA) were performed. There were significant differences in total, anterior and posterior CBF, ICA and VA flow volumes in exacerbated COPD compared to stable COPD. Total CBF was correlated with cross-sectional areas of left and right ICA, whereas independent predictor of total CBF was cross-sectional area of right ICA. Increased CBF might indicate cerebral autoregulation-mediated vasodilatation to overcome COPD exacerbation induced hypoxia.
authors.affiliation: Department of Radiology, Harran University School of Medicine, Sanliurfa, Turkey. drsemayildiz@yahoo.com
authors.forename: Sema
authors.initials: S
authors.lastname: Yildiz
authors.forename: Ihsan
authors.initials: I
authors.lastname: Kaya
authors.forename: Hasan
authors.initials: H
authors.lastname: Cece
authors.forename: Mehmet
authors.initials: M
authors.lastname: Gencer
authors.forename: Zeki
authors.initials: Z
authors.lastname: Ziylan
authors.forename: Funda
authors.initials: F
authors.lastname: Yalcin
authors.forename: Ozlem
authors.initials: O
authors.lastname: Turksoy
mesh_terms: D001783:Blood Flow Velocity; D002343:Carotid Artery, Internal / Q000000981:diagnostic imaging / Q000503:physiopathology*; D002560:Cerebrovascular Circulation; D006801:Humans; D002534:Hypoxia, Brain / Q000000981:diagnostic imaging / Q000209:etiology* / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D029424:Pulmonary Disease, Chronic Obstructive / Q000150:complications* / Q000000981:diagnostic imaging / Q000503:physiopathology*; D014463:Ultrasonography; D014711:Vertebral Artery / Q000000981:diagnostic imaging / Q000503:physiopathology*