title: First description of MR mammographic findings in the tumor bed after intraoperative radiotherapy (IORT) of breast cancer.
abstract: The aim was to investigate changes in the tumor bed on magnetic resonance mammography (MRM) after intraoperative radiotherapy (IORT) and whether they would limit the diagnostic value of posttherapeutic MRM. We retrospectively investigated 36 patients undergoing MRM after IORT (median interval 2.8 years, range 0.4-7.1). Wound cavities with fat necrosis were common after IORT (81%). They were associated with persisting contrast enhancement, i.e., enhancement was mostly seen irrespective of the posttherapeutic interval. It normally presented as rim enhancement and did not cause any diagnostic uncertainty if viewed together with other tissue characteristics. We do not expect a limited diagnostic value of MRM after IORT.
authors.affiliation: Institute of Clinical Radiology and Nuclear Medicine, University Medical Center, Mannheim, Medical Faculty Mannheim, Heidelberg University, Germany. klaus.wasser@umm.de
authors.forename: Klaus
authors.initials: K
authors.lastname: Wasser
authors.forename: Andreas
authors.initials: A
authors.lastname: Schnitzer
authors.forename: Dorothee
authors.initials: D
authors.lastname: Engel
authors.forename: Julia
authors.initials: J
authors.lastname: Krammer
authors.forename: Frederik
authors.initials: F
authors.lastname: Wenz
authors.forename: Uta
authors.initials: U
authors.lastname: Kraus-Tiefenbacher
authors.forename: Marc
authors.initials: M
authors.lastname: Suetterlin
authors.forename: Stefan O
authors.initials: SO
authors.lastname: Schoenberg
authors.forename: Gerald
authors.initials: G
authors.lastname: Weisser
mesh_terms: D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000473:pathology* / Q000532:radiotherapy* / Q000601:surgery; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008327:Mammography / Q000379:methods; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000473:pathology* / Q000517:prevention & control*; D010865:Pilot Projects; D018714:Radiotherapy, Adjuvant; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D016896:Treatment Outcome