title: Breastmilk hepatitis A virus RNA in nursing mothers with acute hepatitis A virus infection.
abstract: Breastmilk specimens from three women with acute hepatitis A virus (HAV) infection were studied. Anti-HAV immunoglobulin M and immunoglobulin G antibodies were detected in serum and breastmilk specimens of the three women. The three women also had serum HAV RNA. However, HAV RNA was detected only in two of the three breastmilk specimens. It is interesting that none of the three infants contracted clinical HAV infection. Furthermore, mothers with HAV infection should not be encouraged to discontinue breastfeeding.
authors.affiliation: Liver Unit, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.
authors.forename: Nili
authors.initials: N
authors.lastname: Daudi
authors.forename: Daniel
authors.initials: D
authors.lastname: Shouval
authors.forename: Chen
authors.initials: C
authors.lastname: Stein-Zamir
authors.forename: Zvi
authors.initials: Z
authors.lastname: Ackerman
mesh_terms: D001942:Breast Feeding; D005260:Female; D006506:Hepatitis A / Q000276:immunology* / Q000378:metabolism; D035922:Hepatitis A Antibodies / Q000235:genetics / Q000378:metabolism*; D006801:Humans; D007231:Infant, Newborn; D018445:Infectious Disease Transmission, Vertical / Q000517:prevention & control*; D008895:Milk, Human / Q000276:immunology* / Q000821:virology; D009035:Mothers; D011247:Pregnancy; D012367:RNA, Viral / Q000302:isolation & purification*; D055815:Young Adult
chemical_list: D035922:Hepatitis A Antibodies; D012367:RNA, Viral