title: Structural investigation of aroylhydrazones in dimethylsulphoxide/water mixtures.
abstract: Molecular structures of aroylhydrazones derived from salicylaldehyde, o-vanilin and nicotinic acid hydrazide in DMSO and DMSO/H(2)O mixtures have been studied by NMR, UV-Vis, ATR and Raman spectroscopy. The addition of water to the system did not induce the tautomeric conversion of the existing form constituted of the ketoamino hydrazide part and the enolimino aldehyde part, but it was involved in the formation of hydrated molecules. Vibrational spectra (ATR and Raman) clearly indicated hydrogen bonding of the studied hydrazones through the carbonyl, amino and hydroxyl groups with water molecules. Increasing the water content conversion from E to Z isomer was not observed.
authors.affiliation: Department of Chemistry, Faculty of Science, University of Zagreb, Horvatovac 102a, 10000 Zagreb, Croatia. ngalic@chem.pmf.hr
authors.forename: Nives
authors.initials: N
authors.lastname: Galić
authors.forename: Adriana
authors.initials: A
authors.lastname: Dijanošić
authors.forename: Darko
authors.initials: D
authors.lastname: Kontrec
authors.forename: Snežana
authors.initials: S
authors.lastname: Miljanić
mesh_terms: D000096:Acetone / Q000737:chemistry; D004121:Dimethyl Sulfoxide / Q000737:chemistry*; D006835:Hydrazones / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D012997:Solvents / Q000737:chemistry; D013056:Spectrophotometry, Ultraviolet; D013059:Spectrum Analysis, Raman; D013237:Stereoisomerism; D014732:Vibration; D014867:Water / Q000737:chemistry*
chemical_list: D006835:Hydrazones; D012997:Solvents; D014867:Water; D000096:Acetone; D004121:Dimethyl Sulfoxide