title: Surface plasmon-coupled emission: what can directional fluorescence bring to the analytical sciences?
abstract: Surface plasmon-coupled emission (SPCE) arose from the integration of fluorescence and plasmonics, two rapidly expanding research fields. SPCE is revealing novel phenomena and has potential applications in bioanalysis, medical diagnostics, drug discovery, and genomics. In SPCE, excited fluorophores couple with surface plasmons on a continuous thin metal film; plasmophores radiate into a higher-refractive index medium with a narrow angular distribution. Because of the directional emission, the sensitivity of this technique can be greatly improved with high collection efficiency. This review describes the unique features of SPCE. In particular, we focus on recent advances in SPCE-based analytical platforms and their applications in DNA sensing and the detection of other biomolecules and chemicals.
authors.affiliation: Department of Chemistry and Key Laboratory of Analytical Sciences, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, China.
authors.forename: Shuo-Hui
authors.initials: SH
authors.lastname: Cao
authors.forename: Wei-Peng
authors.initials: WP
authors.lastname: Cai
authors.forename: Qian
authors.initials: Q
authors.lastname: Liu
authors.forename: Yao-Qun
authors.initials: YQ
authors.lastname: Li
mesh_terms: D000818:Animals; D004247:DNA / Q000032:analysis*; D004867:Equipment Design; D005453:Fluorescence; D005456:Fluorescent Dyes / Q000737:chemistry; D006801:Humans; D007118:Immunoassay / Q000295:instrumentation / Q000379:methods; D011506:Proteins / Q000032:analysis*; D013050:Spectrometry, Fluorescence / Q000379:methods; D020349:Surface Plasmon Resonance / Q000295:instrumentation / Q000379:methods*
chemical_list: D005456:Fluorescent Dyes; D011506:Proteins; D004247:DNA