title: Quinolone-resistant Escherichia coli O127a:K63 serotype with an extended-spectrum-beta-lactamase phenotype from a food poisoning outbreak in China.
abstract: We report an atypical enteropathogenic Escherichia coli O127a:K63 strain with resistance to quinolones and extended-spectrum cephalosporins isolated from a 2010 food poisoning outbreak involving 112 adults in China. Two resistance genes [bla(CTX-M-15), aac(6')-Ib-c] and five mutations (two in gyrA, two in parC, one in parE) coexisted in this enteropathogenic E. coli strain.
authors.affiliation: Institute of Disease Control and Prevention, Academy of Military Medical Sciences, Beijing, China.
authors.forename: Rongzhang
authors.initials: R
authors.lastname: Hao
authors.forename: Shaofu
authors.initials: S
authors.lastname: Qiu
authors.forename: Yong
authors.initials: Y
authors.lastname: Wang
authors.forename: Guang
authors.initials: G
authors.lastname: Yang
authors.forename: Wenli
authors.initials: W
authors.lastname: Su
authors.forename: Lixue
authors.initials: L
authors.lastname: Song
authors.forename: Jia
authors.initials: J
authors.lastname: Zhang
authors.forename: Jiaxu
authors.initials: J
authors.lastname: Chen
authors.forename: Leili
authors.initials: L
authors.lastname: Jia
authors.forename: Ligui
authors.initials: L
authors.lastname: Wang
authors.forename: Hongbin
authors.initials: H
authors.lastname: Song
mesh_terms: D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002511:Cephalosporins / Q000494:pharmacology*; D002681:China / Q000453:epidemiology; D004196:Disease Outbreaks; D024881:Drug Resistance, Bacterial; D004926:Escherichia coli / Q000187:drug effects* / Q000201:enzymology / Q000302:isolation & purification; D004927:Escherichia coli Infections / Q000453:epidemiology* / Q000382:microbiology; D005260:Female; D005517:Foodborne Diseases / Q000453:epidemiology* / Q000382:microbiology; D005798:Genes, Bacterial; D005838:Genotype; D006801:Humans; D008297:Male; D010641:Phenotype; D015363:Quinolones / Q000494:pharmacology*; D055815:Young Adult; D001618:beta-Lactamases / Q000378:metabolism*
chemical_list: D000900:Anti-Bacterial Agents; D002511:Cephalosporins; D015363:Quinolones; D001618:beta-Lactamases