title: Sertoli cell quiescence - new insights.
abstract: It is currently accepted that the Sertoli cells are proliferatively active only during the embryogenesis and early fetal development, seizing to divide after puberty, when the spermatogenic niche is prepared, and they become terminally differentiated. So far, only seasonal breeders from mammals have been reported as having season-dependent variations in adult Sertoli cells number and proliferation activity. In this review, we will try to shed light on testis somatic cell plasticity and discuss new evidence for some unique proliferative features Sertoli cells harbor.
authors.affiliation: Institute of Biology and Immunology of Reproduction, BAS, Sofia 1113, Bulgaria. soren.hayrabedyan@gmail.com
authors.forename: Soren
authors.initials: S
authors.lastname: Hayrabedyan
authors.forename: Krassimira
authors.initials: K
authors.lastname: Todorova
authors.forename: Shina
authors.initials: S
authors.lastname: Pashova
authors.forename: Margarita
authors.initials: M
authors.lastname: Mollova
authors.forename: Nelson
authors.initials: N
authors.lastname: Fernández
mesh_terms: D000818:Animals; D002453:Cell Cycle; D002454:Cell Differentiation; D049109:Cell Proliferation; D006801:Humans; D008297:Male; D051379:Mice; D051381:Rats; D012708:Sertoli Cells / Q000378:metabolism / Q000502:physiology*; D013091:Spermatogenesis; D013737:Testis / Q000166:cytology* / Q000196:embryology