title: A review on cardiovascular diseases originated from subclinical hypothyroidism.
abstract: Thyroid hormones play an important role on the cardiovascular systems and thyroid disorder ultimately have a profound adverse effects on myocardium and vascular functions. There are extensive reports on the role of overt thyroid dysfunction which adversely can modify the cardiovascular metabolism but even at the present of some controversial reports, the subclinical thyroid disorders are able also to manipulate cardiovascular system to some extent. The aim of this study is to review the cardiovascular disorders accompanied with subclinical hypothyroidism. It is concluded that adverse effect of thyroid malfunction on myocardium and vascular organs are through the direct role of thyroid hormone and dyslipidemia on heart muscle cells at nuclear level and vascular system, respectively. It seems many cardiovascular disorders initially would not have been occurred in the first place if the thyroid of affected person had functioned properly, therefore thyroid function tests should be one of a prior laboratory examinations in cardiovascular disorders.
authors.affiliation: Biochemistry and Metabolic Disorder Research Center, Golestan University of Medical Sciences, Gorgan, Iran.
authors.forename: Azad Reza
authors.initials: AR
authors.lastname: Mansourian
mesh_terms: D001808:Blood Vessels / Q000378:metabolism; D002318:Cardiovascular Diseases / Q000209:etiology* / Q000503:physiopathology; D050171:Dyslipidemias / Q000503:physiopathology; D006801:Humans; D007037:Hypothyroidism / Q000150:complications* / Q000503:physiopathology; D009206:Myocardium / Q000378:metabolism; D013963:Thyroid Hormones / Q000378:metabolism
chemical_list: D013963:Thyroid Hormones