title: The effect of trauma center designation on organ donor outcomes in Southern California.
abstract: We sought to investigate the effect of trauma center designation on organ donor outcomes during a 5-year period. A retrospective study of the southern California regional Organ Procurement Organization database comparing trauma centers (n = 25) versus nontrauma centers (n = 171)  and Level I (n = 7) versus Level II (n = 18) trauma centers between 2004 and 2008 was performed. A total of 16,830 referrals were evaluated and 44 per cent were from trauma centers. When compared with nontrauma centers (n = 171), trauma centers (n = 25) had a higher percentage of medically  suitable eligible deaths (29 vs 16%, P < 0.001), total eligible deaths (22 vs 12%, P < 0.001), and eligible donors (14 vs 7%, P < 0.001). Trauma Centers had a significantly higher number of organs procured per donor (4.0 ± 1.6 vs  3.5 ± 1.6, P < 0.001), organs transplanted per donor (OTPD) (3.6 ± 1.8 vs 2.8 ± 1.8, P < 0.001), and higher organ yield (per cent 4 or greater OTPD [48 vs 31%, P < 0.001]). No significant differences were found between Level  I and Level II trauma centers. Trauma centers demonstrate significantly better organ donor outcomes compared with nontrauma centers. Factors responsible for improved outcomes at trauma centers should be evaluated, reproduced, and disseminated to nontrauma centers to alleviate the growing organ  shortage crisis.
authors.affiliation: Department of Surgery, Division of Trauma and Critical Care, Cedars-Sinai Medical Center, Los Angeles, California 90048, USA. ali.salim@cshs.org
authors.forename: Ali
authors.initials: A
authors.lastname: Salim
authors.forename: Cherisse
authors.initials: C
authors.lastname: Berry
authors.forename: Eric J
authors.initials: EJ
authors.lastname: Ley
authors.forename: Danielle
authors.initials: D
authors.lastname: Schulman
authors.forename: Marko
authors.initials: M
authors.lastname: Bukur
authors.forename: Daniel R
authors.initials: DR
authors.lastname: Margulies
authors.forename: Sonia
authors.initials: S
authors.lastname: Navarro
authors.forename: Darren
authors.initials: D
authors.lastname: Malinoski
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002140:California; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D016377:Organ Transplantation; D012189:Retrospective Studies; D013997:Time Factors; D014019:Tissue Donors / Q000600:supply & distribution*; D009927:Tissue and Organ Procurement / Q000458:organization & administration*; D014193:Trauma Centers / Q000706:statistics & numerical data*