title: Conus medullaris syndrome as a complication of radioisotope cisternography.
abstract: OBJECTIVE
  Conus medullaris syndrome (CMS) is a clinical neurologic syndrome caused by a conus medullaris lesion. CMS is a heterogeneous entity with various etiologies such as trauma or a space-occupying lesion. Multiple cases of CMS following spinal anesthesia have been reported, but CMS after radioisotope (RI) cisternography has not yet been reported.
  
  
  METHODS
  We present four patients who developed CMS after RI cisternography.
  
  
  RESULTS
  All experienced neurological deficits such as paraparesis, sensory loss, and urinary incontinence three to four days after RI cisternography. Two showed abnormalities on lumbar magnetic resonance imaging, and three had complete symptom resolution within ten weeks.
  
  
  CONCLUSIONS
  The pathomechanism of the CMS is unclear, but we hypothesize that RI neurotoxicity might be responsible. It is possible that the use of low-dose 99mTc-DTPA or an alternative diagnostic tool such as magnetic resonance cisternography could help to prevent this complication.
authors.affiliation: Department of Neurology, Hanyang University College of Medicine, Seoul, Korea.
authors.forename: Bek-San
authors.initials: BS
authors.lastname: Park
authors.forename: Jinse
authors.initials: J
authors.lastname: Park
authors.forename: Seong-Ho
authors.initials: SH
authors.lastname: Koh
authors.forename: Hojin
authors.initials: H
authors.lastname: Choi
authors.forename: Hyun-Jeung
authors.initials: HJ
authors.lastname: Yu
authors.forename: Koo-Eun
authors.initials: KE
authors.lastname: Lee
authors.forename: Young Joo
authors.initials: YJ
authors.lastname: Lee
authors.forename: Kyu-Yong
authors.initials: KY
authors.lastname: Lee
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D011859:Radiography; D011875:Radionuclide Angiography / Q000009:adverse effects*; D013116:Spinal Cord / Q000000981:diagnostic imaging; D013117:Spinal Cord Compression / Q000209:etiology*