title: Comparison study of biomimetic strontium-doped calcium phosphate coatings by electrochemical deposition and air plasma spray: morphology, composition and bioactive performance.
abstract: In this study, strontium-doped calcium phosphate coatings were deposited by electrochemical deposition and plasma spray under different process parameters to achieve various coating morphologies. The coating composition was investigated by energy dispersive X-ray spectroscopy and X-ray diffraction. The surface morphologies of the coatings were studied through scanning electron microscopy while the cytocompatibility and bioactivity of the strontium-doped calcium phosphate coatings were evaluated using bone cell culture using MC3T3-E1 osteoblast-like cells. The addition of strontium leads to enhanced proliferation suggesting the possible benefits of strontium incorporation in calcium phosphate coatings. The morphology and composition of deposited coatings showed a strong influence on the growth of cells.
authors.affiliation: Stony Brook University, 314 Old Engineering, Stony Brook, NY 11794-2275, USA.
authors.forename: Ling
authors.initials: L
authors.lastname: Li
authors.forename: Xia
authors.initials: X
authors.lastname: Lu
authors.forename: Yizhi
authors.initials: Y
authors.lastname: Meng
authors.forename: Christopher M
authors.initials: CM
authors.lastname: Weyant
mesh_terms: D000388:Air; D032701:Biomimetics; D002130:Calcium Phosphates / Q000737:chemistry*; D055664:Electrochemical Techniques; D008855:Microscopy, Electron, Scanning; D013324:Strontium / Q000737:chemistry*; D014961:X-Ray Diffraction
chemical_list: D002130:Calcium Phosphates; C020243:calcium phosphate; D013324:Strontium