title: Hemostatic matrix application after open synovectomy in a hemophilic patient.
abstract: Recurrent, spontaneous bleeding is common in patients with hemophilia. The joints are commonly and repeatedly affected, and this can result in chronic synovitis and joint damage. Synoviorthesis or synovectomy are indicated after failure of appropriate medical management. Hemostasis in the perioperative period is paramount in these patients. We report a case study of a patient with hemophilia A inhibitors undergoing open synovectomy complicated by postoperative bleeding. In addition to an infusion of bypassing agents due to the presence of inhibitors, a topical hemostatic agent, FLOSEAL, and absorbable Gelfoam were applied. Hemostasis was achieved rapidly. The patient recovered without complications.
authors.affiliation: Department of Orthopaedic Surgery, University of Puerto Rico, School of Medicine, San Juan, Puerto Rico. manuel.garcia8@upr.edu
authors.forename: Manuel
authors.initials: M
authors.lastname: García Aríz
authors.forename: Omar
authors.initials: O
authors.lastname: Pérez-Carrasquillo
authors.forename: Charles E
authors.initials: CE
authors.lastname: Zierenberg
authors.forename: Jorge
authors.initials: J
authors.lastname: Cheleuitte
authors.forename: Jhon A
authors.initials: JA
authors.lastname: Guerra
authors.forename: Pedro J
authors.initials: PJ
authors.lastname: Santiago-Borrero
mesh_terms: D000293:Adolescent; D005781:Gelatin Sponge, Absorbable / Q000627:therapeutic use*; D006395:Hemarthrosis / Q000209:etiology / Q000601:surgery*; D006467:Hemophilia A / Q000150:complications / Q000601:surgery*; D006490:Hemostatics / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D019106:Postoperative Hemorrhage / Q000517:prevention & control*; D013585:Synovitis / Q000209:etiology / Q000601:surgery*; D016896:Treatment Outcome
chemical_list: C411004:FloSeal Matrix; D006490:Hemostatics