title: Subcellular distribution of CdSe quantum dots (QDs) in breast cancer cells.
abstract: In spite of great advances in conventional cancer diagnosis and treatment, the early recognition and characterization for various cancers remain a technological bottleneck. The combined characteristics of board absorption and narrow emission make quantum dots (QDs) desirable fluorescent labels for cancer imaging and other applications in the biomedical field. In the current study, to the best of our knowledge, we first evidenced the preferential accumulation of QDs in cytoplasm of breast cancer cells. QDs therefore reveal considerable potentials in both tumor imaging and therapeutic application.
authors.affiliation: State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China.
authors.forename: Lei
authors.initials: L
authors.lastname: Hong
authors.forename: Zhe
authors.initials: Z
authors.lastname: Wang
authors.forename: Lin
authors.initials: L
authors.lastname: Yuan
authors.forename: Jianhua
authors.initials: J
authors.lastname: Tan
authors.forename: Lixin
authors.initials: L
authors.lastname: Wang
authors.forename: Guangbo
authors.initials: G
authors.lastname: Qu
authors.forename: Daoqiang
authors.initials: D
authors.lastname: Zhang
authors.forename: Ronghai
authors.initials: R
authors.lastname: Lin
authors.forename: Sijin
authors.initials: S
authors.lastname: Liu
mesh_terms: D001943:Breast Neoplasms / Q000737:chemistry* / Q000473:pathology*; D019187:Cadmium Compounds / Q000737:chemistry*; D045744:Cell Line, Tumor; D004058:Diffusion; D006801:Humans; D045663:Quantum Dots; D018036:Selenium Compounds / Q000737:chemistry*; D013347:Subcellular Fractions / Q000737:chemistry*
chemical_list: D019187:Cadmium Compounds; D018036:Selenium Compounds; C058667:cadmium selenide