title: Microwave ablation treatment of liver cancer with a 2,450-MHz cooled-shaft antenna: pilot study on safety and efficacy.
abstract: To evaluate efficacy of microwave ablation in a primary clinical study, sixty patients (44 men, 16 women; mean age 53 years) with 96, 1-8 cm (mean 3.20 ± 0.17 cm) liver cancers were treated with 2,450-MHz internally cooled-shaft antenna. Complete ablation (CA) and local tumor progression (LTP) rates as well as complications were determined. CA rates in small (<3.0 cm), intermediate (3.1-5.0 cm) and large (5.1-8.0 cm) liver cancers were 96.4% (54/56), 92.3% (24/26) and 78.6% (11/14), respectively. During a mean follow-up period of 17.17 ∓ 6.52 months, LTP occurred in five (5.21%) treated cases. There was no significant difference in the CA and LTP rates between the HCC and liver metastasis patient subgroups (P<0.05). Microwave ablation provides a reliable, efficient, and safe technique to perform hepatic tumor ablation.
authors.affiliation: Department of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
authors.forename: De-Chao
authors.initials: DC
authors.lastname: Jiao
authors.forename: Qi
authors.initials: Q
authors.lastname: Zhou
authors.forename: Xin-Wei
authors.initials: XW
authors.lastname: Han
authors.forename: Ya-Feng
authors.initials: YF
authors.lastname: Wang
authors.forename: Gang
authors.initials: G
authors.lastname: Wu
authors.forename: Jian-Zhuang
authors.initials: JZ
authors.lastname: Ren
authors.forename: Yan-Li
authors.initials: YL
authors.lastname: Wang
authors.forename: Peng-Xu
authors.initials: PX
authors.lastname: Ding
authors.forename: Ji
authors.initials: J
authors.lastname: Ma
authors.forename: Ming-Ti
authors.initials: MT
authors.lastname: Fu
mesh_terms: D000328:Adult; D000368:Aged; D006528:Carcinoma, Hepatocellular / Q000000981:diagnostic imaging / Q000556:secondary / Q000601:surgery*; D017115:Catheter Ablation / Q000295:instrumentation*; D003080:Cold Temperature; D004564:Electrocoagulation; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D008297:Male; D008872:Microwaves / Q000627:therapeutic use*; D008875:Middle Aged; D010865:Pilot Projects; D011379:Prognosis; D014057:Tomography, X-Ray Computed; D055815:Young Adult