title: Trapezial metastasis as the first indication of primary non-small cell carcinoma of the lung.
abstract: Metastasis to the bones of the hand and wrist is not common, and its discovery may reveal an advanced primary tumor located centrally. Clinically, hand metastasis is hard to differentiate from other more common hand pathologies. Its rarity, coupled with a lack of unique clinical manifestations, makes hand and wrist metastasis difficult to diagnose. However, its diagnosis is critical to initiate an appropriate course of treatment. We present a patient in whom lung carcinoma metastasis to the trapezium was definitively diagnosed upon surgical management of symptoms that were consistent with thumb carpometacarpal arthritis.
authors.affiliation: Department of Orthopaedic Surgery, Stanford University Medical Center, Redwood City, CA 94063, USA.
authors.forename: Yohan
authors.initials: Y
authors.lastname: Song
authors.forename: Jeffrey
authors.initials: J
authors.lastname: Yao
mesh_terms: D000368:Aged; D001182:Arthroscopy; D001706:Biopsy; D001859:Bone Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary*; D002289:Carcinoma, Non-Small-Cell Lung / Q000473:pathology*; D003937:Diagnosis, Differential; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology*; D008297:Male; D010003:Osteoarthritis / Q000473:pathology / Q000601:surgery; D011471:Prostatic Neoplasms / Q000473:pathology*; D011859:Radiography; D051222:Trapezium Bone / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery