title: [Clinicopathological features and prognosis of colorectal cancer patients with preoperative cancer-related anemia].
abstract: OBJECTIVE
  To analyze the clinicopathological features and prognosis of colorectal cancer patients with preoperative cancer-related anemia.
  
  
  METHODS
  Clinical data of 354 patients with colorectal cancer in the Second Affiliated Hospital of Guangzhou Medical College from January 2003 to July 2009 were analyzed retrospectively. Those with hemoglobin(Hb)<120 g/L before surgery were defined as cancer-related anemia.
  
  
  RESULTS
  Of the 354 colorectal cancer cases, 195 were males and 159 were females. The median age was 65(range 22-92) years. Preoperative cancer-related anemia tended to be occurred in female(P<0.01) and those with preoperative albumin ≤35 g/L (P<0.01), right colon cancer(P<0.01) and full-thickness invasion(P<0.05). Cox regression analysis showed preoperative cancer-related anemia was an independent unfavorable factor for overall survival (HR=1.60, 95% CI:1.05-2.44; P<0.05), but not for disease-free survival (HR=1.43, 95% CI:0.97-2.12; P>0.05) in colorectal cancer.
  
  
  CONCLUSIONS
  Preoperative cancer-related anemia plays an important role in the development and prognosis of colorectal cancer and great attention should be paid to clinical practice.
authors.affiliation: Department of Gastrointestinal Surgery, Guangzhou Medical College, Guangzhou, China.
authors.forename: Yi-sheng
authors.initials: YS
authors.lastname: Wei
authors.forename: Chu-yuan
authors.initials: CY
authors.lastname: Hong
authors.forename: Chu-xiong
authors.initials: CX
authors.lastname: Zhao
authors.forename: Guo-jian
authors.initials: GJ
authors.lastname: Liang
authors.forename: Guo-qiang
authors.initials: GQ
authors.lastname: Wang
authors.forename: Xiang-cai
authors.initials: XC
authors.lastname: Zou
authors.forename: Hang
authors.initials: H
authors.lastname: Lin
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000740:Anemia / Q000209:etiology*; D015179:Colorectal Neoplasms / Q000150:complications* / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012189:Retrospective Studies; D055815:Young Adult