title: Effects of iron glycine chelate on growth, tissue mineral concentrations, fecal mineral excretion, and liver antioxidant enzyme activities in broilers.
abstract: The study was conducted to determine the effects of iron glycine chelate (Fe-Gly) on growth, tissue mineral concentrations, fecal mineral excretion, and liver antioxidant enzyme activities in broilers. A total of 360 1-day-old commercial broilers (Ross × Ross) were randomly allotted to six dietary treatments with six replications of ten chicks per replicate. Broilers were fed a control diet with no Fe supplementation, while five other treatments consisted of 40, 80, 120, and 160 mg Fe/kg diets from Fe-Gly, and 160 mg Fe/kg from ferrous sulfate, respectively. After a 42-day feeding trial, the results showed that 120 and 160 mg Fe/kg as Fe-Gly improved the average daily gain (P < 0.05) and average daily feed intake (P < 0.05) of broilers (4-6 weeks). Addition with 120 and 160 mg Fe/kg from Fe-Gly and 160 mg Fe/kg from FeSO(4) increased Fe concentration in serum (P < 0.05), liver (P < 0.05), breast muscle (P < 0.05), tibia (P < 0.05), and feces (P < 0.01) at 21 and 42 days. There were linear responses to the addition of Fe-Gly from 0 to 160 mg/kg Fe on Fe concentration in serum (21 days, P = 0.005; 42 days, P = 0.001), liver (P = 0.001), breast muscle (P = 0.001), tibia (P = 0.001), and feces (21 days, P = 0.011; 42 days, P = 0.032). Liver Cu/Zn superoxide dismutase activities of chicks were increased by the addition of 80, 120, and 160 mg Fe/kg as Fe-Gly to diets at 42 days. There were no differences in liver catalase activities of chicks among the treatments (P > 0.05). This study indicates that addition with Fe-Gly could improve growth performance and iron tissue storage and improves the antioxidant status of broiler chickens.
authors.affiliation: The Key Laboratory of Molecular Animal Nutrition, Ministry of Education, College of Animal Science, Zhejiang University, Zi Jin Gang Campus, Hangzhou, 310029, People's Republic of China.
authors.forename: W Q
authors.initials: WQ
authors.lastname: Ma
authors.forename: H
authors.initials: H
authors.lastname: Sun
authors.forename: Y
authors.initials: Y
authors.lastname: Zhou
authors.forename: J
authors.initials: J
authors.lastname: Wu
authors.forename: J
authors.initials: J
authors.lastname: Feng
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000378:metabolism*; D002374:Catalase / Q000378:metabolism; D002645:Chickens; D003300:Copper / Q000097:blood / Q000378:metabolism; D005243:Feces / Q000737:chemistry*; D005998:Glycine / Q000031:analogs & derivatives* / Q000494:pharmacology; D007501:Iron / Q000097:blood / Q000378:metabolism; D008099:Liver / Q000187:drug effects / Q000201:enzymology* / Q000378:metabolism*; D008345:Manganese / Q000097:blood / Q000378:metabolism; D013482:Superoxide Dismutase / Q000378:metabolism; D015032:Zinc / Q000097:blood / Q000378:metabolism
chemical_list: D000975:Antioxidants; C101403:iron-glycine chelate; D008345:Manganese; D003300:Copper; D007501:Iron; D002374:Catalase; D013482:Superoxide Dismutase; D015032:Zinc; D005998:Glycine