title: Tetraisopropyldisiloxane-1,3-diyl as a versatile protecting group for pentopyranosides.
abstract: The protecting group tetraisopropyldisiloxane-1,3-yl has been investigated for simultaneous protection of two hydroxyls on pentopyranosides. Methyl α-D-xylopyranoside is protected in excellent regioselectivity and high yield to form the 2,3-protected xylopyranoside whereas methyl β-D-xylopyranoside gives the 3,4-protected product also with excellent regioselectivity.
authors.affiliation: Center for Analysis and Synthesis, Lund University, PO Box 124, SE-221 00 Lund, Sweden. richard.johnsson@organic.lu.se
authors.forename: Richard
authors.initials: R
authors.lastname: Johnsson
mesh_terms: D008759:Methylglycosides / Q000737:chemistry; D015394:Molecular Structure; D012821:Silanes / Q000737:chemistry*; D013237:Stereoisomerism; D013379:Substrate Specificity; D014994:Xylose / Q000737:chemistry
chemical_list: D008759:Methylglycosides; D012821:Silanes; C059468:disiloxane; C050519:methyl xylopyranoside; D014994:Xylose