title: Bortezomib-induced severe autonomic neuropathy.
abstract: Peripheral neuropathy is a known side effect of bortezomib therapy. Acute autonomic neuropathy may also follow treatment with this cytotoxic agent used for treatment of multiple myeloma. Here, we report clinical characteristics and patterns of autonomic involvement in a 75-year-old patient who presented with recurring syncopes.
authors.affiliation: Department of Neurology and Clinical Neurophysiology, Autonomic Laboratory, HELIOS-Klinikum Wuppertal, University of Witten/Herdecke, Heusnerstr. 40, 42283 Wuppertal, Germany.
authors.forename: A
authors.initials: A
authors.lastname: Stratogianni
authors.forename: M
authors.initials: M
authors.lastname: Tosch
authors.forename: H
authors.initials: H
authors.lastname: Schlemmer
authors.forename: J
authors.initials: J
authors.lastname: Weis
authors.forename: I
authors.initials: I
authors.lastname: Katona
authors.forename: S
authors.initials: S
authors.lastname: Isenmann
authors.forename: C A
authors.initials: CA
authors.lastname: Haensch
mesh_terms: D000368:Aged; D000970:Antineoplastic Agents / Q000009:adverse effects*; D001342:Autonomic Nervous System Diseases / Q000139:chemically induced* / Q000175:diagnosis / Q000503:physiopathology; D001897:Boronic Acids / Q000009:adverse effects*; D000069286:Bortezomib; D006801:Humans; D008297:Male; D009101:Multiple Myeloma / Q000188:drug therapy*; D010523:Peripheral Nervous System Diseases / Q000139:chemically induced* / Q000175:diagnosis / Q000503:physiopathology; D011719:Pyrazines / Q000009:adverse effects*; D012720:Severity of Illness Index
chemical_list: D000970:Antineoplastic Agents; D001897:Boronic Acids; D011719:Pyrazines; D000069286:Bortezomib