title: Comparative effect of lornoxicam and paracetamol in pain relief in endometrial sampling.
abstract: We conducted a study to compare the analgesic effect of oral lornoxicam and oral paracetamol before endometrial sampling for benign conditions. This prospective, double-blind, randomized study was conducted on sixty women underwent endometrial sampling for benign indications, from November 2010 to April 2011. The patients were divided into two groups (lornoxicam and paracetamol group) and both administered drugs (8 mg oral lornoxicam or 500 mg oral paracetamol) one hour before the procedure. Pain scores, by VAS (Visual analog scale) pain score, were recorded 0, 30 and 60 minutes after the procedure and compared. All patients gave informed consent to the study. Statistical analyses were carried out by using the statistical packages for SPSS 15.0 for Windows (SPSS Inc., Chicago, IL, USA). There was no statistically significant difference between the groups about the demographic parameters (p > 0.05). Lornoxicam group showed lower VAS pain score than the paracetamol group (p < 0.05). A total of thirteen patients took additional analgesic in two groups (p < 0.05). According to the current study, oral lornoxicam is more effective in pain relief than oral paracetamol in patients underwent endometrial sampling.
authors.affiliation: Ergani State Hospital, Department of Obstetrics and Gynecology, Diyarbakir, Turkey. alijnk@hotmail.com
authors.forename: Ali Irfan
authors.initials: AI
authors.lastname: Guzel
authors.forename: Umur
authors.initials: U
authors.lastname: Kuyumcuoglu
authors.forename: Yusuf
authors.initials: Y
authors.lastname: Celik
mesh_terms: D000082:Acetaminophen / Q000008:administration & dosage*; D000328:Adult; D004311:Double-Blind Method; D016889:Endometrial Neoplasms / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008875:Middle Aged; D059408:Pain Management; D010147:Pain Measurement / Q000187:drug effects*; D010894:Piroxicam / Q000008:administration & dosage / Q000031:analogs & derivatives*; D011446:Prospective Studies; D014421:Turkey
chemical_list: D010894:Piroxicam; D000082:Acetaminophen; C059451:lornoxicam