title: Surveillance of transmitted HIV drug resistance using matched plasma and dried blood spot specimens from voluntary counseling and testing sites in Ho Chi Minh City, Vietnam, 2007-2008.
abstract: During 2007-2008, surveillance of transmitted human immunodeficiency virus (HIV) drug resistance (TDR) was performed following World Health Organization guidance among clients with newly diagnosed HIV infection attending voluntary counseling and testing (VCT) sites in Ho Chi Minh City (HCMC), Vietnam. Moderate (5%-15%) TDR to nonnucleoside reverse-transcriptase inhibitors (NNRTIs) was observed among VCT clients aged 18-21 years. Follow-up surveillance of TDR in HCMC and other geographic regions of Vietnam is warranted. Data generated will guide the national HIV drug resistance surveillance strategy and support selection of current and future first-line antiretroviral therapy and HIV prevention programs.
authors.affiliation: Department of Health and Human Services/US Centers for Disease Control and Prevention, Atlanta, GA 30333, USA. vif8@cdc.gov
authors.forename: Nguyen Bui
authors.initials: NB
authors.lastname: Duc
authors.forename: Bui Thu
authors.initials: BT
authors.lastname: Hien
authors.forename: Nick
authors.initials: N
authors.lastname: Wagar
authors.forename: Tran Hong
authors.initials: TH
authors.lastname: Tram
authors.forename: Le Truong
authors.initials: le T
authors.lastname: Giang
authors.forename: Chunfu
authors.initials: C
authors.lastname: Yang
authors.forename: Mitchell I
authors.initials: MI
authors.lastname: Wolfe
authors.forename: Nguyen Tran
authors.initials: NT
authors.lastname: Hien
authors.forename: Nguyen Anh
authors.initials: NA
authors.lastname: Tuan
mesh_terms: D000554:Ambulatory Care Facilities; D044966:Anti-Retroviral Agents / Q000494:pharmacology*; D001774:Blood Chemical Analysis / Q000379:methods*; D059788:Dried Blood Spot Testing; D024882:Drug Resistance, Viral; D060005:Genotyping Techniques; D006678:HIV / Q000145:classification* / Q000187:drug effects / Q000235:genetics; D015658:HIV Infections / Q000097:blood* / Q000453:epidemiology* / Q000635:transmission / Q000821:virology; D006801:Humans; D011159:Population Surveillance; D014744:Vietnam / Q000453:epidemiology; D035141:Voluntary Programs; D055815:Young Adult
chemical_list: D044966:Anti-Retroviral Agents