title: Management of periocular basal cell carcinoma by Mohs micrographic surgery.
abstract: OBJECTIVE
  To determine the success of Mohs micrographic surgery (MMS) for periocular basal cell carcinoma (BCC) at a tertiary referral centre in the UK.
  
  
  METHODS
  A retrospective interventional case series covering 5 years of practice.
  
  
  METHODS
  Review of medical records of 104 consecutive patients who underwent MMS for confirmed periocular BCC. The main outcome measure was biopsy-proven recurrence of BCC at the same anatomical location after MMS. Secondary outcome measures included tumour site, histological subtype and length of follow-up.
  
  
  RESULTS
  104 patients underwent MMS for periocular BCC from January 2003 to July 2008. 63 (62%) of the surgeries were for primary BCC and 25 procedures (25%) were for recurrent or residual BCC. 64% of tumours were nodular BCC. The mean follow-up was 28 months (range 1-85 months). Six recurrences were identified in total. The recurrence rate following MMS for primary BCC was 1.6% (1 patient) compared to 20% (5 patients) in the patient group treated for residual or recurrent tumours. The mean time to recurrence was 39 months (range 16-71 months).
  
  
  CONCLUSIONS
  MMS for primary BCC has a very high success rate but the recurrence rate increases significantly in cases of recurrent or residual tumours.
authors.affiliation: Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, England. andre@doctors.org.uk
authors.forename: Andre S
authors.initials: AS
authors.lastname: Litwin
authors.forename: Ed
authors.initials: E
authors.lastname: Rytina
authors.forename: Thomas
authors.initials: T
authors.lastname: Ha
authors.forename: Cornelius
authors.initials: C
authors.lastname: René
authors.forename: Simon A
authors.initials: SA
authors.lastname: Woodruff
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002280:Basal Cell Carcinoma / Q000473:pathology / Q000601:surgery*; D005142:Eyelid Neoplasms / Q000473:pathology / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D015580:Mohs Surgery; D009364:Neoplasm Recurrence, Local / Q000473:pathology / Q000601:surgery; D011446:Prospective Studies; D012189:Retrospective Studies; D012878:Skin Neoplasms / Q000473:pathology / Q000601:surgery*; D016896:Treatment Outcome