title: Treatment of severe sepsis and septic shock in critically ill patients.
authors.forename: Silvio A
authors.initials: SA
authors.lastname: Namendys-Silva
authors.forename: Marisol
authors.initials: M
authors.lastname: Hernández-Garay
mesh_terms: D000890:Anti-Infective Agents / Q000627:therapeutic use; D002496:Central Venous Pressure; D016638:Critical Illness; D017052:Hospital Mortality; D006801:Humans; D017410:Practice Guidelines as Topic; D011486:Protein C / Q000627:therapeutic use; D011994:Recombinant Proteins / Q000627:therapeutic use; D018805:Sepsis / Q000401:mortality / Q000628:therapy*; D012772:Shock, Septic / Q000401:mortality / Q000628:therapy*
chemical_list: D000890:Anti-Infective Agents; D011486:Protein C; D011994:Recombinant Proteins; C421124:drotrecogin alfa activated