title: [Living birth after partial hysterectomy for chemorefractory gestational choriocarcinoma].
abstract: Chemotherapy is the reference treatment for gestational trophoblastic neoplasia. In case of chemoresistance, hysterectomy has to be considered even in women wishing to conceive. A 31-year-old nulliparous patient presented a recurrent invasive mole, despite two regimens of chemotherapy. She underwent a partial uterine resection of an intramyometrial choriocarcinoma followed by a third-line regimen. Two years later she gave birth by cesarean section at 32 weeks of amenorrhea to a healthy child after a spontaneous pregnancy. In order to preserve patient's fertility, conservative uterine surgery is an alternative to hysterectomy for selected chemoresistant gestational trophoblastic neoplasia.
authors.affiliation: Centre français de référence des maladies trophoblastiques, université Lyon-1, CHU Lyon-Sud, 165, chemin du Grand-Revoyet, 69495 Pierre-Bénite, France.
authors.forename: F
authors.initials: F
authors.lastname: Couder
authors.forename: F
authors.initials: F
authors.lastname: Golfier
authors.forename: F
authors.initials: F
authors.lastname: Vaudoyer
authors.forename: J
authors.initials: J
authors.lastname: Massardier
authors.forename: J-P
authors.initials: JP
authors.lastname: Guastalla
authors.forename: T
authors.initials: T
authors.lastname: Hajri
authors.forename: D
authors.initials: D
authors.lastname: Raudrant
mesh_terms: D000328:Adult; D002585:Cesarean Section; D002822:Choriocarcinoma / Q000188:drug therapy / Q000601:surgery*; D019008:Drug Resistance, Neoplasm; D005260:Female; D059247:Fertility Preservation / Q000379:methods; D005865:Gestational Age; D006801:Humans; D007044:Hysterectomy; D007231:Infant, Newborn; D050498:Live Birth; D011247:Pregnancy; D014594:Uterine Neoplasms / Q000188:drug therapy / Q000601:surgery*; D014599:Uterus / Q000601:surgery