title: Mouse models for the study of fungal pneumonia: a collection of detailed experimental protocols for the study of Coccidioides, Cryptococcus, Fusarium, Histoplasma and combined infection due to Aspergillus-Rhizopus.
abstract: Mouse models have facilitated the study of fungal pneumonia. In this report, we present the working protocols of groups that are working on the following pathogens: Aspergillus, Coccidioides, Cryptococcus, Fusarium, Histoplasma and Rhizopus. We describe the experimental procedures and the detailed methods that have been followed in the experienced laboratories to study pulmonary fungal infection; we also discuss the anticipated results and technical notes, and provide the practical advices that will help the users of these models.
authors.affiliation: Division of Infectious Diseases, Harvard Medical School and Massachusetts General Hospital Boston, MA, USA.
authors.forename: Maged
authors.initials: M
authors.lastname: Muhammed
authors.forename: Marta
authors.initials: M
authors.lastname: Feldmesser
authors.forename: Lisa F
authors.initials: LF
authors.lastname: Shubitz
authors.forename: Michail S
authors.initials: MS
authors.lastname: Lionakis
authors.forename: Anita
authors.initials: A
authors.lastname: Sil
authors.forename: Yan
authors.initials: Y
authors.lastname: Wang
authors.forename: Justin
authors.initials: J
authors.lastname: Glavis-Bloom
authors.forename: Russell E
authors.initials: RE
authors.lastname: Lewis
authors.forename: John N
authors.initials: JN
authors.lastname: Galgiani
authors.forename: Arturo
authors.initials: A
authors.lastname: Casadevall
authors.forename: Dimitrios P
authors.initials: DP
authors.lastname: Kontoyiannis
authors.forename: Eleftherios
authors.initials: E
authors.lastname: Mylonakis
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D005658:Fungi / Q000472:pathogenicity; D007756:Laboratory Animal Science / Q000379:methods*; D008172:Lung Diseases, Fungal / Q000382:microbiology* / Q000473:pathology*; D051379:Mice; D008828:Microbiological Techniques / Q000379:methods*; D010336:Pathology / Q000379:methods*