title: The standardized and mini versions of the PAQLQ are valid, reliable, and responsive measurement tools.
abstract: OBJECTIVE
  The Paediatric Asthma Quality of Life Questionnaire (PAQLQ) is a validated tool developed to assess the impact of symptoms on quality of life. Here we assess the validity, reliability and responsiveness of two new simpler versions of this questionnaire: the Standardised PAQLQ and the MiniPAQLQ.
  
  
  METHODS
  Participants included 42 children with asthma, who completed the PAQLQ, PAQLQ(S), MiniPAQLQ, Asthma Control Questionnaire, and Health Utilities Index at baseline, one, five and nine weeks. Concordance between questionnaires was examined using intraclass correlation coefficients (ICC), bias by paired Student's t-tests and closeness of association by Pearson correlation coefficients.
  
  
  RESULTS
  Correlation coefficients for each of the corresponding domains of the PAQLQ with the PAQLQ(S) were strong (r>0.97), and moderate to strong (r=0.50-0.94) with the MiniPAQLQ. Reliability was strong for both the PAQLQ(S) (ICC>0.89) and MiniPAQLQ (ICC>0.91). The responsiveness index values for the PAQLQ(S) (0.96) and the MiniPAQLQ (1.05) were both higher than that of the original PAQLQ (0.90). Cross sectional and longitudinal correlation coefficients were similar for all three instruments.
  
  
  CONCLUSIONS
  The PAQLQ(S) and the MiniPAQLQ are valid, reliable and responsive to change. They can be used with confidence for long-term monitoring in clinical trials.
authors.affiliation: Education for Health, The Athenaeum, 10 Church Street, Warwick CV34 4AB, Warwickshire, UK.
authors.forename: Annie
authors.initials: A
authors.lastname: Wing
authors.forename: Jane
authors.initials: J
authors.lastname: Upton
authors.forename: Klas
authors.initials: K
authors.lastname: Svensson
authors.forename: Peter
authors.initials: P
authors.lastname: Weller
authors.forename: Monica
authors.initials: M
authors.lastname: Fletcher
authors.forename: Samantha
authors.initials: S
authors.lastname: Walker
mesh_terms: D000293:Adolescent; D000465:Algorithms; D001249:Asthma / Q000175:diagnosis / Q000503:physiopathology / Q000523:psychology; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D011594:Psychometrics; D011788:Quality of Life; D015203:Reproducibility of Results; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires / Q000592:standards*