title: Evaluation of bacterial growth inhibition by mercaptopropionic acid in metallo-β-lactamase detection on multidrug-resistant Acinetobacter baumannii.
abstract: BACKGROUND
  Metallo-β-lactamase (MBL) has been reported all over the world.
  
  
  METHODS
  The inhibitory effect of mercaptopropionic acid (MPA) on bacterial growth was evaluated by comparison between disk diffusion and broth dilution methodology with determination of the minimum inhibitory concentration (MIC) for multidrug-resistant Acinetobacter baumanni strains.
  
  
  RESULTS
  MPA significantly inhibited growth of the strains.
  
  
  CONCLUSIONS
  The use of MPA can affect the results in phenotypic methods of MBL detection.
authors.affiliation: Laboratório de Bacteriologia, Departamento de Análises Clínicas e Toxicológicas, Centro de Ciências da Saúde, Universidade Federal de Santa Maria, Santa Maria, RS.
authors.forename: Letícia Eichstaedt
authors.initials: LE
authors.lastname: Mayer
authors.forename: Rosmari
authors.initials: R
authors.lastname: Hörner
authors.forename: Maisa Kräulich
authors.initials: MK
authors.lastname: Tizotti
authors.forename: Rosiéli
authors.initials: R
authors.lastname: Martini
authors.forename: Magda Cristina Souza Marques
authors.initials: MC
authors.lastname: Roehrs
authors.forename: Cláudia Barbisan
authors.initials: CB
authors.lastname: Kempfer
mesh_terms: D015097:3-Mercaptopropionic Acid / Q000494:pharmacology*; D040981:Acinetobacter baumannii / Q000187:drug effects* / Q000201:enzymology / Q000254:growth & development; D024901:Drug Resistance, Multiple, Bacterial; D004791:Enzyme Inhibitors / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests / Q000379:methods; D001618:beta-Lactamases / Q000096:biosynthesis / Q000187:drug effects*
chemical_list: D004791:Enzyme Inhibitors; D015097:3-Mercaptopropionic Acid; D001618:beta-Lactamases