title: Palladium-catalyzed asymmetric 6-endo cyclization of dienamides with substituent-driven activation.
abstract: Chiral 2-piperidinone compounds with various C-6 substituents were successfully synthesized via a Pd-catalyzed asymmetric 6-endo cyclization of dienamides, which were evidently activated by both N-p-toluenesulfonyl and C-3 ester substituents.
authors.affiliation: School of Science and Technology, Kwansei Gakuin University, Gakuen 2-1, Sanda, Hyogo 669-1337, Japan. h-tsuchi@chem.sci.osaka-u.ac.jp
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Tsuchikawa
authors.forename: Yuya
authors.initials: Y
authors.lastname: Maekawa
authors.forename: Shigeo
authors.initials: S
authors.lastname: Katsumura
mesh_terms: D000577:Amides / Q000737:chemistry*; D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D003500:Cyclization; D010165:Palladium / Q000737:chemistry*; D010881:Piperidones / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D000577:Amides; D010881:Piperidones; D010165:Palladium; C043384:2-piperidone