title: Clinical research informatics: a conceptual perspective.
abstract: Clinical research informatics is the rapidly evolving sub-discipline within biomedical informatics that focuses on developing new informatics theories, tools, and solutions to accelerate the full translational continuum: basic research to clinical trials (T1), clinical trials to academic health center practice (T2), diffusion and implementation to community practice (T3), and 'real world' outcomes (T4). We present a conceptual model based on an informatics-enabled clinical research workflow, integration across heterogeneous data sources, and core informatics tools and platforms. We use this conceptual model to highlight 18 new articles in the JAMIA special issue on clinical research informatics.
authors.affiliation: Department of Pediatrics, University of Colorado, Aurora, Colorado 80045, USA. michael.kahn@ucdenver.edu
authors.forename: Michael G
authors.initials: MG
authors.lastname: Kahn
authors.forename: Chunhua
authors.initials: C
authors.lastname: Weng
mesh_terms: D035843:Biomedical Research; D006801:Humans; D008490:Medical Informatics; D008962:Models, Theoretical; D057170:Translational Research, Biomedical