title: Large cell lymphoma associated with prosthetic joint debris.
abstract: Soft tissue reactions to materials in joint prostheses include discoloration, fibrosis, florid histiocytic reaction, and granulomatous inflammation with foreign body giant cell reaction. Clinical manifestations include pain and swelling. We report a case of temporomandibular joint Proplast-Teflon prosthesis, followed by the development of large cell lymphoma in the left parotid gland 10 years after joint replacement. While it is unclear whether the implant directly contributed to the development of lymphoma, this association has not been previously documented, prompting this report.
authors.affiliation: Department of Pathology, Louisiana State University Health Sciences Center, Shreveport, USA.
authors.forename: Menchu G
authors.initials: MG
authors.lastname: Ong
authors.forename: G E
authors.initials: GE
authors.lastname: Ghali
authors.forename: Diana
authors.initials: D
authors.lastname: Veillon
authors.forename: James
authors.initials: J
authors.lastname: Cotelingam
mesh_terms: D019643:Arthroplasty, Replacement / Q000009:adverse effects / Q000295:instrumentation / Q000379:methods; D019544:Equipment Failure Analysis; D006801:Humans; D007595:Joint Prosthesis / Q000009:adverse effects*; D016403:Lymphoma, Large B-Cell, Diffuse / Q000473:pathology / Q000601:surgery; D008297:Male; D008875:Middle Aged; D010306:Parotid Gland / Q000473:pathology / Q000601:surgery; D010307:Parotid Neoplasms / Q000209:etiology / Q000473:pathology / Q000601:surgery; D011428:Proplast / Q000009:adverse effects* / Q000627:therapeutic use; D013704:Temporomandibular Joint / Q000601:surgery*; D013995:Time; D016896:Treatment Outcome
chemical_list: D011428:Proplast