title: Off-pump coronary surgery may reduce stroke, respiratory failure, and mortality in octogenarians.
abstract: BACKGROUND
  Octogenarians are a challenging group of patients referred for cardiac surgery. The aim of this study is to assess early outcomes of coronary artery bypass grafting (CABG) performed in the elderly population.
  
  
  METHODS
  We performed a meta-analysis of all published observational studies comparing early results of conventional CABG surgery and off-pump CABG surgery in patients aged 80 years or older. The outcomes of interest were mortality, stroke, respiratory failure, renal failure, incidence of support with intraaortic balloon pump, and incidence of postoperative atrial fibrillation. The random effects model was used.
  
  
  RESULTS
  Fourteen studies were analyzed. The total number of included subjects was 4,991, of whom 3,113 underwent conventional CABG surgery (62.4%), and 1,878 (37.6%) underwent off-pump CABG surgery. The rates of mortality, stroke, and respiratory failure were significantly higher in the conventional CABG surgery group.
  
  
  CONCLUSIONS
  These results confirm that off-pump CABG surgery remains a valuable option of surgical myocardial revascularization, and may optimize the outcome in senior patients.
authors.affiliation: Department of Cardiovascular Surgery, Medical University of Gdansk, Gdansk, Poland. rpgab@gumed.edu.pl
authors.forename: Rafal
authors.initials: R
authors.lastname: Pawlaczyk
authors.forename: Dariusz
authors.initials: D
authors.lastname: Swietlik
authors.forename: Romuald
authors.initials: R
authors.lastname: Lango
authors.forename: Jan
authors.initials: J
authors.lastname: Rogowski
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001281:Atrial Fibrillation / Q000517:prevention & control; D001026:Coronary Artery Bypass / Q000009:adverse effects / Q000401:mortality; D047549:Coronary Artery Bypass, Off-Pump / Q000009:adverse effects* / Q000401:mortality; D005260:Female; D017052:Hospital Mortality; D006801:Humans; D007423:Intra-Aortic Balloon Pumping; D008297:Male; D011183:Postoperative Complications / Q000517:prevention & control*; D051437:Renal Insufficiency / Q000517:prevention & control; D012131:Respiratory Insufficiency / Q000517:prevention & control*; D020521:Stroke / Q000517:prevention & control*