title: A case of hypereosinophilic syndrome presenting with multiorgan infarctions associated with disseminated intravascular coagulation.
abstract: Thromboembolism is one of the most critical complications of hypereosinophilic syndrome (HES). We report here a case of multi-organ infarctions related to HES. A 23-year-old woman was referred to our hospital with hemoptysis. Not only pulmonary, but also renal and splenic infarctions were detected on computed tomography images. Blood tests showed profound peripheral eosinophilia. She was diagnosed with HES with disseminated intravascular coagulation (DIC). We initiated infusion of corticosteroids, which effectively suppressed peripheral eosinophilia. However, consumptive coagulopathy did not improve and intracerebral hemorrhage related to thrombosis then developed. Addition of interferon-alpha resulted in the correction of the DIC associated with HES.
authors.affiliation: Division of Allergy, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
authors.forename: Sun-Mi
authors.initials: SM
authors.lastname: Park
authors.forename: Ji-Won
authors.initials: JW
authors.lastname: Park
authors.forename: Sung-Min
authors.initials: SM
authors.lastname: Kim
authors.forename: Eun-Hee
authors.initials: EH
authors.lastname: Koo
authors.forename: Jin-Young
authors.initials: JY
authors.lastname: Lee
authors.forename: Chul-Su
authors.initials: CS
authors.lastname: Lee
authors.forename: Dong-Chull
authors.initials: DC
authors.lastname: Choi
authors.forename: Byung-Jae
authors.initials: BJ
authors.lastname: Lee