title: Changes in the maternal cytokine profile in pregnancies complicated by fetal growth restriction.
abstract: Fetal growth restriction (FGR) is an important and poorly understood condition of pregnancy, which results in significant fetal, neonatal and long-term morbidity and mortality. The aetiology of FGR is unknown and is likely to result from sub-optimal placental implantation and feto-maternal immunological interaction. The diagnostic criteria for FGR vary between studies, and the condition often occurs with preeclampsia (PET). We present a review of studies of maternal cytokines in FGR and compare these with studies of Small for Gestational Age and PET pregnancies.
authors.affiliation: Queen Charlotte's and Chelsea Hospital, Imperial College, London, UK.
authors.forename: Edward
authors.initials: E
authors.lastname: Mullins
authors.forename: Tomas
authors.initials: T
authors.lastname: Prior
authors.forename: Irene
authors.initials: I
authors.lastname: Roberts
authors.forename: Sailesh
authors.initials: S
authors.lastname: Kumar
mesh_terms: D000818:Animals; D016207:Cytokines / Q000378:metabolism*; D010064:Embryo Implantation; D005260:Female; D005317:Fetal Growth Retardation / Q000175:diagnosis / Q000209:etiology / Q000378:metabolism*; D006801:Humans; D007231:Infant, Newborn; D007236:Infant, Small for Gestational Age / Q000378:metabolism; D011225:Pre-Eclampsia / Q000175:diagnosis / Q000378:metabolism; D011247:Pregnancy
chemical_list: D016207:Cytokines