title: Design of chiral sulfoxide-Schiff base hybrids and their application in Cu-catalyzed asymmetric Henry reactions.
abstract: A new class of chiral sulfoxide-Schiff base ligands has been developed by the rational combination of two privileged chiral backbones. These sulfoxide-Schiff base ligands were found to be highly efficient for Cu-catalyzed asymmetric Henry reactions (up to 98% yield and 96% ee).
authors.affiliation: Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, 152 Luoyu Road, Wuhan, Hubei 430079, China.
authors.forename: Hong-Gang
authors.initials: HG
authors.lastname: Cheng
authors.forename: Liang-Qiu
authors.initials: LQ
authors.lastname: Lu
authors.forename: Tao
authors.initials: T
authors.lastname: Wang
authors.forename: Jia-Rong
authors.initials: JR
authors.lastname: Chen
authors.forename: Wen-Jing
authors.initials: WJ
authors.lastname: Xiao
mesh_terms: D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D018360:Crystallography, X-Ray; D008024:Ligands; D008958:Models, Molecular; D012545:Schiff Bases / Q000737:chemistry*; D013454:Sulfoxides / Q000737:chemistry*
chemical_list: D008024:Ligands; D012545:Schiff Bases; D013454:Sulfoxides; D003300:Copper