title: [Botulinum toxin A after microvascular ALT flap in a patient with (corrected) squamous cell carcinoma of the tongue].
abstract: We report the case of a 23-year-old man presenting with a cT4 cN1 M0squamous cell carcinoma of the right tongue. After tumor resection and covering of the defect with a microvascular anterolateral thigh (ALT) flap, the patient showed distinct drooling without any substantial regression after anticholinergic therapy. For this reason 75 units of Botox® were injected into the submandibular and parotid glands. After the intraglandular injections, good reduction of saliva secretion was achieved. The treatment improved flap healing, aspiration and patient satisfaction. Injection of botulinum toxin A into the salivary glands is a sufficient therapy for postoperative hypersalivation.
authors.affiliation: Klinik und Poliklinik für Hals-Nasen-Ohrenheilkunde, Universitätsmedizin Göttingen, Robert-Koch-Str. 40, 37099, Göttingen, Deutschland.
authors.forename: F
authors.initials: F
authors.lastname: Ihler
authors.forename: R
authors.initials: R
authors.lastname: Laskawi
authors.forename: C
authors.initials: C
authors.lastname: Matthias
authors.forename: H H
authors.initials: HH
authors.lastname: Rustenbeck
authors.forename: M
authors.initials: M
authors.lastname: Canis
mesh_terms: D019274:Botulinum Toxins, Type A / Q000627:therapeutic use*; D002294:Carcinoma, Squamous Cell / Q000150:complications / Q000601:surgery*; D006801:Humans; D008297:Male; D009465:Neuromuscular Agents / Q000627:therapeutic use; D019647:Oral Surgical Procedures / Q000009:adverse effects*; D012798:Sialorrhea / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology*; D014062:Tongue Neoplasms / Q000150:complications / Q000601:surgery*; D016896:Treatment Outcome; D014945:Wound Healing / Q000187:drug effects; D055815:Young Adult
chemical_list: D009465:Neuromuscular Agents; D019274:Botulinum Toxins, Type A