title: The involvement of audio-motor coupling in the music-supported therapy applied to stroke patients.
abstract: Music-supported therapy (MST) has been developed recently to improve the use of the affected upper extremity after stroke. MST uses musical instruments, an electronic piano and an electronic drum set emitting piano sounds, to retrain fine and gross movements of the paretic upper extremity. In this paper, we first describe the rationale underlying MST, and we review the previous studies conducted on acute and chronic stroke patients using this new neurorehabilitation approach. Second, we address the neural mechanisms involved in the motor movement improvements observed in acute and chronic stroke patients. Third, we provide some recent studies on the involvement of auditory-motor coupling in the MST in chronic stroke patients using functional neuroimaging. Finally, these ideas are discussed and focused on understanding the dynamics involved in the neural circuit underlying audio-motor coupling and how functional connectivity could help to explain the neuroplastic changes observed after therapy in stroke patients.
authors.affiliation: Cognition and Brain Plasticity Group, Bellvitge Biomedical Research Institute, L'Hospitalet de Llobregat, Barcelona, Spain. antoni.rodriguez@icrea.es
authors.forename: Antoni
authors.initials: A
authors.lastname: Rodriguez-Fornells
authors.forename: Nuria
authors.initials: N
authors.lastname: Rojo
authors.forename: Julià L
authors.initials: JL
authors.lastname: Amengual
authors.forename: Pablo
authors.initials: P
authors.lastname: Ripollés
authors.forename: Eckart
authors.initials: E
authors.lastname: Altenmüller
authors.forename: Thomas F
authors.initials: TF
authors.lastname: Münte
mesh_terms: D001303:Auditory Cortex / Q000503:physiopathology; D001307:Auditory Perception / Q000502:physiology; D001921:Brain / Q000503:physiopathology; D056228:Feedback, Sensory / Q000502:physiology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008959:Models, Neurological; D008960:Models, Psychological; D009044:Motor Cortex / Q000503:physiopathology; D009048:Motor Skills / Q000502:physiology; D009147:Music Therapy; D009415:Nerve Net / Q000503:physiopathology; D009473:Neuronal Plasticity / Q000502:physiology; D009488:Neurosciences; D020521:Stroke / Q000503:physiopathology* / Q000523:psychology / Q000628:therapy*; D000071939:Stroke Rehabilitation