title: Metal-free ortho C-H borylation of 2-phenoxypyridines under mild conditions.
abstract: An efficient metal-free ortho C-H borylation has been developed via sequential borylation of substituted 2-phenoxypyridines with BBr3 following esterification with pinacol. The corresponding aryl boronates were obtained in good yields. The synthesized aryl boronates can be easily transformed into various useful products. Therefore, the present method makes functionalizations of aryl C-H bonds easy.
authors.affiliation: Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University, Beijing 100084, P. R. China, and Key Laboratory of Chemical Biology (Guangdong Province), Graduate School of Shenzhen, Tsinghua University, Shenzhen 518057, P. R. China.
authors.forename: Liting
authors.initials: L
authors.lastname: Niu
authors.forename: Haijun
authors.initials: H
authors.lastname: Yang
authors.forename: Ruji
authors.initials: R
authors.lastname: Wang
authors.forename: Hua
authors.initials: H
authors.lastname: Fu
mesh_terms: D001896:Boron Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*; D011725:Pyridines / Q000737:chemistry*
chemical_list: D001896:Boron Compounds; D011725:Pyridines; D010165:Palladium