title: [Neurocysticercosis: an neglected disease in Chile].
abstract: Neurocysticercosis (NCC) is not a notifiable disease in Chile and has received little attention on the national medical literature. In order to evaluate the relevance and clinical features of the disease, we performed a retrospective analysis in a general hospital of five cases of NCC during a 11 years period. Age ranged from 3 to 63 years and all had history of living or visiting southern Chile. Three patients had a solitary parenchymal cyst in vesicular or granulomatous stages and presented with generalized seizures. Their outcome was favorable after anticonvulsant and albendazole therapy and cysts reduced in size and calcified during follow-up. The other 2 patients had extra-parenchymal or mixed forms, including a pregnant woman with intraventricular cysts who developed endocraneal hypertension and recurrent dysfunction of her ventriculoperitoneal shunt. This patient died after discharge despite an initial favorable evolution with steroids and high-dose albendazole. This case series showed that NCC is still an epidemiological and clinical problem in Chile, affects patients within a wide range of age including children, requires multidisciplinary therapeutic interventions, and has two clinical presentations with different prognosis including one malignant form. To control this infection, a surveillance or reporting system should be initiated.
authors.affiliation: Servicio de Infectología, Departamento de Medicina, Hospital Militar de Santiago, Chile. albertifica@gmail.com
authors.forename: Alberto
authors.initials: A
authors.lastname: Fica C
authors.forename: Marcelo
authors.initials: M
authors.lastname: Castro S
authors.forename: Andrés
authors.initials: A
authors.lastname: Soto S
authors.forename: Carlos
authors.initials: C
authors.lastname: Flores M
authors.forename: Carolina
authors.initials: C
authors.lastname: Oelker B
authors.forename: Thomas
authors.initials: T
authors.lastname: Weitzel
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D002677:Chile / Q000453:epidemiology; D005260:Female; D006801:Humans; D015994:Incidence; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D058069:Neglected Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology; D020019:Neurocysticercosis / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology; D011247:Pregnancy; D015597:Pregnancy Complications, Parasitic / Q000175:diagnosis / Q000188:drug therapy; D015995:Prevalence; D012189:Retrospective Studies; D012307:Risk Factors; D055815:Young Adult