title: Portal hypertension in children.
abstract: The main causes of intrahepatic portal hypertension in children are cirrhosis and congenital hepatic fibrosis. Non cirrhotic portal hypertension in children is mostly due to extrahepatic portal vein obstruction. In half of cases, no underlying disorder is found. The meso-Rex bypass is the preferred treatment, when it is possible. The closest to the portal vein the obstruction, the highest the risk of esophagogastric varices.
authors.affiliation: Department of Paediatric Surgery and Transplantation Center, Bambino Gesù Childrens Hospital, Roma, Italy.
authors.forename: Chiara
authors.initials: C
authors.lastname: Grimaldi
authors.forename: Jean
authors.initials: J
authors.lastname: de Ville de Goyet
authors.forename: Valerio
authors.initials: V
authors.lastname: Nobili
mesh_terms: D002648:Child; D016145:Endoscopy, Digestive System; D004932:Esophageal and Gastric Varices / Q000209:etiology / Q000601:surgery; D006801:Humans; D006975:Hypertension, Portal / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy*; D008103:Liver Cirrhosis / Q000601:surgery; D016031:Liver Transplantation; D011169:Portal Vein / Q000000981:diagnostic imaging / Q000601:surgery; D011170:Portasystemic Shunt, Surgical; D011433:Propranolol / Q000008:administration & dosage; D018608:Ultrasonography, Doppler; D014652:Vascular Diseases / Q000150:complications / Q000601:surgery; D014665:Vasodilator Agents / Q000008:administration & dosage
chemical_list: D014665:Vasodilator Agents; D011433:Propranolol