title: A new and efficient method for the synthesis of 3,4-disubstituted pyrrolidine-2,5-diones.
abstract: A newly found reaction for the synthesis of 3,4-disubstituted 1-hydroxy-pyrrolidine-2,5-diones from 3-substituted coumarins and nitromethane has been elaborated. The reaction involved a simple and convenient experimental procedure. The applicability of the rearrangement reaction is determined.
authors.affiliation: Sofia University St. Kliment Ohridski, Faculty of Chemistry and Pharmacy, 1, J. Bourchier Blvd., Sofia 1126, Bulgaria.
authors.forename: Eleonora D
authors.initials: ED
authors.lastname: Ilieva
authors.forename: Nevena I
authors.initials: NI
authors.lastname: Petkova
authors.forename: Rositca D
authors.initials: RD
authors.lastname: Nikolova
mesh_terms: D001578:Benzopyrans / Q000737:chemistry; D003374:Coumarins / Q000737:chemistry*; D018360:Crystallography, X-Ray; D009682:Magnetic Resonance Spectroscopy; D008697:Methane / Q000031:analogs & derivatives* / Q000737:chemistry; D015394:Molecular Structure; D009595:Nitroparaffins / Q000737:chemistry*; D013237:Stereoisomerism; D013388:Succinimides / Q000138:chemical synthesis*; D013696:Temperature
chemical_list: D001578:Benzopyrans; D003374:Coumarins; D009595:Nitroparaffins; D013388:Succinimides; D008697:Methane; C008640:nitromethane