title: A family cluster of tuberculosis cases, including a case of acquired multidrug resistant tuberculosis.
abstract: Although the number of tuberculosis cases in the US is at an all-time low, with progressive declines seen for the past 17 years, many goals in the tuberculosis elimination process remain unrealized. This report describes a cluster of four tuberculosis cases in a family, including one case of acquired multidrug resistant tuberculosis. It also underscores some important issues in tuberculosis control today, including significant disparities in the foreign-born population with multidrug resistant tuberculosis as a looming problem, as well as utilization of therapeutic drug level monitoring in complicated cases.
authors.affiliation: Tulane University Health Sciences Center, Preventive Medicine Residency Program, USA.
authors.forename: Julie
authors.initials: J
authors.lastname: Holden
authors.forename: Louis
authors.initials: L
authors.lastname: Trachtman
mesh_terms: D000328:Adult; D000995:Antitubercular Agents / Q000008:administration & dosage*; D023801:Directly Observed Therapy / Q000379:methods; D018563:Disease Notification; D016903:Drug Monitoring / Q000379:methods; D024901:Drug Resistance, Multiple, Bacterial; D054242:Emigrants and Immigrants; D005192:Family Health; D005260:Female; D054624:Health Status Disparities; D054625:Healthcare Disparities / Q000706:statistics & numerical data*; D006630:Hispanic or Latino; D006801:Humans; D007223:Infant; D008145:Louisiana / Q000453:epidemiology; D008297:Male; D009169:Mycobacterium tuberculosis / Q000302:isolation & purification / Q000472:pathogenicity; D016896:Treatment Outcome; D014376:Tuberculosis / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology / Q000503:physiopathology
chemical_list: D000995:Antitubercular Agents