title: One-step synthesis of highly functionalized monofluorinated cyclopropanes from electron-deficient alkenes.
abstract: The unique combination of Zn/LiCl allowed generation of reactive zinc enolate from ethyl dibromofluoroacetate. This fluorinated enolate reacts efficiently with a wide range of functionalized electron-deficient alkenes to afford the corresponding monofluorinated cyclopropylcarboxylates in good yields.
authors.affiliation: INSA de Rouen, UMR 6014 & FR 3038, C.O.B.R.A. Université de Rouen, 1 rue Tesnière 76131 Mont-Saint-Aignan Cedex, France.
authors.forename: Pavel
authors.initials: P
authors.lastname: Ivashkin
authors.forename: Samuel
authors.initials: S
authors.lastname: Couve-Bonnaire
authors.forename: Philippe
authors.initials: P
authors.lastname: Jubault
authors.forename: Xavier
authors.initials: X
authors.lastname: Pannecoucke
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D003500:Cyclization; D003521:Cyclopropanes / Q000138:chemical synthesis* / Q000737:chemistry; D006845:Hydrocarbons, Fluorinated / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D013237:Stereoisomerism; D015032:Zinc
chemical_list: D000475:Alkenes; D003521:Cyclopropanes; D006845:Hydrocarbons, Fluorinated; D015032:Zinc