title: [Severe mitral regurgitation as the first symptom of systemic lupus erythematosus in a young women required mitral valve replacement].
abstract: Systemic lupus erythematosus (SLE) is an autoimmune disorder resulting in multiorgan inflammatory damage. The heart is  frequently involved in SLE. The best known cardiac manifestations are pericarditis and Libman-Saks endocarditis. Severe  valvular impairment is rather rare and occurs in few years and in advanced stage of the disease. In this study we report a case  of a young women with SLE and heart failure due to mitral regurgitation as the first manifestation of the disease.
authors.affiliation: II Klinika Kardiologii, Katedra Kardiologii, Uniwersytet Medyczny im. Karola Marcinkowskiego, Poznań. anowicka@ump.edu.pl
authors.forename: Anna
authors.initials: A
authors.lastname: Nowicka
authors.forename: Anna
authors.initials: A
authors.lastname: Piątkowska
authors.forename: Wojciech
authors.initials: W
authors.lastname: Biegalski
authors.forename: Rafał
authors.initials: R
authors.lastname: Dankowski
authors.forename: Marek
authors.initials: M
authors.lastname: Michalski
authors.forename: Katarzyna
authors.initials: K
authors.lastname: Szymanowska
authors.forename: Andrzej
authors.initials: A
authors.lastname: Szyszka
authors.forename: Marek
authors.initials: M
authors.lastname: Jemielity
authors.forename: Wojciech
authors.initials: W
authors.lastname: Seniuk
authors.forename: Piotr
authors.initials: P
authors.lastname: Sosnowski
mesh_terms: D018618:Echocardiography, Doppler, Color / Q000379:methods; D005260:Female; D006333:Heart Failure / Q000209:etiology* / Q000601:surgery; D019918:Heart Valve Prosthesis Implantation / Q000379:methods; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications*; D008943:Mitral Valve / Q000601:surgery*; D008944:Mitral Valve Insufficiency / Q000209:etiology* / Q000601:surgery; D013997:Time Factors; D055815:Young Adult