title: Tibiofemoral cartilage contact biomechanics in patients after reconstruction of a ruptured anterior cruciate ligament.
abstract: We investigated the in vivo cartilage contact biomechanics of the tibiofemoral joint in patients after reconstruction of a ruptured anterior cruciate ligament (ACL). A dual fluoroscopic and MR imaging technique was used to investigate the cartilage contact biomechanics of the tibiofemoral joint during in vivo weight-bearing flexion of the knee in eight patients 6 months following clinically successful reconstruction of an acute isolated ACL rupture. The location of tibiofemoral cartilage contact, size of the contact area, cartilage thickness at the contact area, and magnitude of the cartilage contact deformation of the ACL-reconstructed knees were compared with those previously measured in intact (contralateral) knees and ACL-deficient knees of the same subjects. Contact biomechanics of the tibiofemoral cartilage after ACL reconstruction were similar to those measured in intact knees. However, at lower flexion, the abnormal posterior and lateral shift of cartilage contact location to smaller regions of thinner tibial cartilage that has been described in ACL-deficient knees persisted in ACL-reconstructed knees, resulting in an increase of the magnitude of cartilage contact deformation at those flexion angles. Reconstruction of the ACL restored some of the in vivo cartilage contact biomechanics of the tibiofemoral joint to normal. Clinically, recovering anterior knee stability might be insufficient to prevent post-operative cartilage degeneration due to lack of restoration of in vivo cartilage contact biomechanics.
authors.affiliation: Bioengineering Laboratory, Massachusetts General Hospital/Harvard Medical School, Boston, MA 02114, USA.
authors.forename: Ali
authors.initials: A
authors.lastname: Hosseini
authors.forename: Samuel
authors.initials: S
authors.lastname: Van de Velde
authors.forename: Thomas J
authors.initials: TJ
authors.lastname: Gill
authors.forename: Guoan
authors.initials: G
authors.lastname: Li
mesh_terms: D000328:Adult; D000070598:Anterior Cruciate Ligament Injuries; D059549:Anterior Cruciate Ligament Reconstruction; D001696:Biomechanical Phenomena; D002358:Cartilage, Articular / Q000473:pathology / Q000503:physiopathology*; D005260:Female; D006801:Humans; D007718:Knee Injuries / Q000473:pathology / Q000503:physiopathology* / Q000601:surgery; D007719:Knee Joint / Q000473:pathology / Q000503:physiopathology*; D008297:Male; D020127:Recovery of Function; D055815:Young Adult