title: A new cyclododeca[d]oxazole derivative from Streptomyces spp. CIBYL1.
abstract: A novel secondary metabolite, N-trans-cinnamoyl 2-amino-3a,4,5,6,7,8,9,10,11,12,13,13a-dodecahydrocyclododeca[d]oxazole (1), was isolated from Streptomyces spp. CIBYL1, along with five known compounds, pimprinine (2), (3R,4S,5R,6R)-3,4,5,6-tetrahydro-4-hydroxy-3,5,6-trimethyl-2H-pyran-2-one (3), indolyl-3-carboxylic acid (4), 2-phenylacetamide (5) and di(1H-pyrrol-2-yl)methanone (6). The structures of these metabolites were elucidated on the basis of extensive analysis of spectroscopic data, including OR, IR, HRMS, 1D and 2D NMR data and chemical derivation.
authors.affiliation: Center for Natural Products Research , Chengdu Institute of Biology of the Chinese Academy of Sciences, Chengdu, People's Republic of China.
authors.forename: Xiang
authors.initials: X
authors.lastname: Pu
authors.forename: Guangzhou
authors.initials: G
authors.lastname: Li
authors.forename: Tao
authors.initials: T
authors.lastname: Yang
authors.forename: Guoyou
authors.initials: G
authors.lastname: Li
authors.forename: Jinhai
authors.initials: J
authors.lastname: Yi
authors.forename: Guolin
authors.initials: G
authors.lastname: Zhang
authors.forename: Yinggang
authors.initials: Y
authors.lastname: Luo
mesh_terms: D043822:Cyclodecanes / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010080:Oxazoles / Q000737:chemistry*; D013302:Streptomyces / Q000737:chemistry*
chemical_list: D043822:Cyclodecanes; D010080:Oxazoles