title: Antimicrobial effect of linalool and α-terpineol against periodontopathic and cariogenic bacteria.
abstract: Linalool and α-terpineol exhibited strong antimicrobial activity against periodontopathic and cariogenic bacteria. However, their concentration should be kept below 0.4 mg/ml if they are to be used as components of toothpaste or gargling solution. Moreover, other compounds with antimicrobial activity against periodontopathic and cariogenic bacteria should be used in combination.
authors.affiliation: Department of Oral Biochemistry, School of Dentistry, Chosun University, Dong-Gu, Gwangju, Republic of Korea.
authors.forename: Soon-Nang
authors.initials: SN
authors.lastname: Park
authors.forename: Yun Kyong
authors.initials: YK
authors.lastname: Lim
authors.forename: Marcelo Oliveira
authors.initials: MO
authors.lastname: Freire
authors.forename: Eugene
authors.initials: E
authors.lastname: Cho
authors.forename: Dongchun
authors.initials: D
authors.lastname: Jin
authors.forename: Joong-Ki
authors.initials: JK
authors.lastname: Kook
mesh_terms: D000080462:Acyclic Monoterpenes; D000900:Anti-Bacterial Agents / Q000494:pharmacology* / Q000633:toxicity; D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects; D000081005:Cyclohexane Monoterpenes; D053138:Cyclohexenes / Q000494:pharmacology* / Q000633:toxicity; D003731:Dental Caries / Q000382:microbiology; D004353:Drug Evaluation, Preclinical; D005673:Fusobacterium / Q000187:drug effects; D006801:Humans; D008826:Microbial Sensitivity Tests; D039821:Monoterpenes / Q000494:pharmacology* / Q000633:toxicity; D009822:Oils, Volatile / Q000494:pharmacology* / Q000633:toxicity; D015661:Pasteurellaceae / Q000187:drug effects; D010510:Periodontal Diseases / Q000382:microbiology; D017861:Porphyromonas / Q000187:drug effects; D018720:Prevotella / Q000187:drug effects; D013295:Streptococcus mutans / Q000187:drug effects; D016986:Streptococcus sobrinus / Q000187:drug effects
chemical_list: D000080462:Acyclic Monoterpenes; D000900:Anti-Bacterial Agents; D000081005:Cyclohexane Monoterpenes; D053138:Cyclohexenes; D039821:Monoterpenes; D009822:Oils, Volatile; C016775:alpha-terpineol; C018584:linalool