title: Pressure-volume index-based volume calculation of contrast medium for atlanto-occipital myelography in dogs.
abstract: Subarachnoid pressure recordings were made during atlanto-occipital myelography in 45 dogs with clinical signs of spinal disease. Iohexol was injected at a dosage of 0.3 ml/kg body weight and simultaneous pressure values were recorded in the cerebellomedullary cistern. The mean subarachnoid pressure was 9 ± 3 mmHg before and 70 ± 32 mmHg at the end of administration. From the pressure change induced by the volume load, the pressure-volume index (PVI) of the subarachnoid space was calculated and found to be in close correlation with body weight and the crown-rump length (r = 0.94 and 0.87). Using the estimated PVI values, the appropriate volume of contrast medium can be calculated for an animal according to body weight. Dogs of a large body size require relatively less contrast medium than small-sized dogs (range 0.17-0.35 ml/kg). This calculated volume is unlikely to increase the subarachnoid pressure above 40 mmHg as a specific pressure limit. Using these data, simplified recommendations for the choice of contrast medium volumes have been generated.
authors.affiliation: Department of Surgery and Ophthalmology, Szent Istvan University, Budapest, Hungary. arany.toth.attila@aotk.szie.hu
authors.forename: Attila
authors.initials: A
authors.lastname: Arany-Tóth
authors.forename: Péter
authors.initials: P
authors.lastname: Csébi
authors.forename: Jenő
authors.initials: J
authors.lastname: Reiczigel
authors.forename: Tibor
authors.initials: T
authors.lastname: Németh
mesh_terms: D000818:Animals; D001269:Atlanto-Occipital Joint; D001835:Body Weight; D003287:Contrast Media / Q000008:administration & dosage*; D004285:Dogs; D005260:Female; D007278:Injections, Spinal; D007427:Intracranial Pressure; D007472:Iohexol / Q000008:administration & dosage; D008297:Male; D009192:Myelography / Q000379:methods / Q000662:veterinary*; D013122:Spinal Diseases / Q000000981:diagnostic imaging / Q000662:veterinary*
chemical_list: D003287:Contrast Media; D007472:Iohexol