title: Verrucous hyperplasia: A clinico-pathological study.
abstract: BACKGROUND
  Oral verrucous hyperplasia (OVH) is a premalignant lesion that may transform into an oral cancer.
  
  
  OBJECTIVE
  The present retrospective study was carried out to analyze the clinico-pathological features of verrucous hyperplasia (VH).
  
  
  METHODS
  Total 19 diagnosed cases of verrucous hyperplasia were retrospectively analyzed for demographic, clinical and histopathological features including dysplasia.
  
  
  RESULTS
  Average age of occurrence of lesion was 4 (th) decade of life, with male predominance (2:1) and common site of occurrence being buccal mucosa. Clinically it present as verrucous exophytic growth with sharp or blunt projections on surface, which corresponds histologically. Tobacco lime quid placement in buccal vestibule was key etiologic factor. Histopathologicaly 68% cases showed dysplasia out of which moderate dysplasia predominates (42%). Moderately dysplastic cases were found to be associated with mixed habit pattern. Maximum cases were treated with excision.
  
  
  CONCLUSIONS
  Biopsy specimen comprising of adjacent normal epithelium is key in distinguishing verrucous hyperplasia from verrucous carcinoma. Clinical behavior and recurrence potential needs to be assessed with long term follow up studies.
authors.affiliation: Department of Oral and Maxillofacial Pathology, Government Dental College and Hospital, Medical Campus, Nagpur, Maharashtra, India.
authors.forename: Vinay K
authors.initials: VK
authors.lastname: Hazarey
authors.forename: Sindhu M
authors.initials: SM
authors.lastname: Ganvir
authors.forename: Ashish S
authors.initials: AS
authors.lastname: Bodhade