title: The effect of Breezy candy on halitosis: a double-blind, controlled, and randomized study.
abstract: Halitosis (bad breath) is a common condition that is socially crippling for vast parts of the population and results from malodorous volatile sulfur compounds, which are by-products of oral bacteria. In this doubled-blind, randomized study, 75 subjects with halitosis were evaluated. The participants were treated with or without abrasive microcapsules (candy) containing zinc gluconate 0.5%, propolis 2%, and a combination of both (zinc 0.25% and propolis 1%). The halitosis was assessed by a Halimeter, a portable instrument that measures the emission of volatile sulfur compounds at different time exposures to the treatments. Breezy candy (which is sugar-free) was found effective in the treatment of halitosis for up to 4 hours. While treatment with regular candy (group 1, traditional candy without abrasive particles) showed reduction in malodor of 10%, Breezy candy showed reduction of up to 60% in malodor (P < .0001). Since this was not a longitudinal study, the total duration of the effect was not assessed. Breezy candy in the abrasive form with zinc additive had the best potential to positively affect malodor when treating patients with halitosis. The combined effect of abrasion by microcapsules with zinc supplement represents a novel and successful approach for the treatment of halitosis.
authors.affiliation: Institute of Dentistry and Oral-Maxillofacial Surgery, Hillel Yaffe Medical Center, Technion, Haifa, Israel.
authors.forename: Shlomo
authors.initials: S
authors.lastname: Barak
authors.forename: Joseph
authors.initials: J
authors.lastname: Katz
mesh_terms: D000328:Adult; D002182:Candy; D004311:Double-Blind Method; D005260:Female; D005942:Gluconates / Q000627:therapeutic use; D006209:Halitosis / Q000178:diet therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011429:Propolis / Q000627:therapeutic use; D013457:Sulfur Compounds / Q000032:analysis; D013549:Sweetening Agents / Q000627:therapeutic use*; D055815:Young Adult
chemical_list: D005942:Gluconates; D013457:Sulfur Compounds; D013549:Sweetening Agents; D011429:Propolis; C030691:gluconic acid