title: Memory-based pre-attentive auditory N1 elicited by sound movement.
abstract: Quickly detecting changes in the surrounding environment is one of the most important functions of sensory processing. Comparison of a new event with preceding sensory conditions is necessary for the change-detection process. A sudden change in a continuous sound elicits auditory evoked potentials that peak approximately 100 ms after the onset of the change (Change-N1). In the present study, we recorded Change-N1 under an oddball paradigm in 19 healthy subjects using an abruptly moving sound (SM-stimulus) as a deviant stimulus and investigated effects of the probability of the SM-stimulus to reveal whether Change-N1 is a memory-based response. We compared the amplitude and latency of Change-N1 elicited by the SM-stimulus among three probability conditions (33, 50 and 100%). As the probability of the SM-stimulus decreased, the amplitude of Change-N1 increased and its latency decreased. The present results indicate that the preceding sensory history affects Change-N1 elicited by the SM-stimulus.
authors.affiliation: Department of Psychiatry, Division of Neuroscience, Mie University Graduate School of Medicine, 2-174 Edobashi, Tsu, Mie 514-8507, Japan.
authors.forename: Keiko
authors.initials: K
authors.lastname: Ohoyama
authors.forename: Eishi
authors.initials: E
authors.lastname: Motomura
authors.forename: Koji
authors.initials: K
authors.lastname: Inui
authors.forename: Makoto
authors.initials: M
authors.lastname: Nishihara
authors.forename: Naofumi
authors.initials: N
authors.lastname: Otsuru
authors.forename: Motoyasu
authors.initials: M
authors.lastname: Oi
authors.forename: Ryusuke
authors.initials: R
authors.lastname: Kakigi
authors.forename: Motohiro
authors.initials: M
authors.lastname: Okada
mesh_terms: D000161:Acoustic Stimulation / Q000379:methods; D000328:Adult; D001288:Attention / Q000502:physiology*; D001307:Auditory Perception / Q000502:physiology*; D004569:Electroencephalography / Q000379:methods; D005072:Evoked Potentials, Auditory / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D008568:Memory / Q000502:physiology*; D015233:Models, Statistical; D011930:Reaction Time / Q000502:physiology; D013017:Sound Localization / Q000502:physiology; D055815:Young Adult