title: Atypical orofacial conditions in Noonan syndrome: a case report.
abstract: Noonan syndrome (NS) is a relatively common condition characterized by chest deformation, congenital heart disease, short stature and distinctive facial features. Due to its genetic heterogeneity NS patients exhibit a range of clinical signs. Severe gingivitis and supernumerary teeth are rarely seen in connection with NS. In addition, there has not been a report on NS patients with atypical bilateral enlargement of the mental foramens and inferior-alveolar canals. This case report describes a NS patient who has undergone growth hormone (GH) therapy and is presenting with classical and rare NS phenotypes.
authors.affiliation: Arizona School of Dentistry & Oral Health, A. T. Still University, Mesa, AZ, USA.
authors.forename: Leo
authors.initials: L
authors.lastname: Toureno
authors.forename: Jae Hyun
authors.initials: JH
authors.lastname: Park
mesh_terms: D000293:Adolescent; D005146:Facial Asymmetry / Q000209:etiology; D005891:Gingivitis / Q000209:etiology*; D013006:Growth Hormone / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008310:Malocclusion / Q000209:etiology*; D009634:Noonan Syndrome / Q000150:complications* / Q000188:drug therapy; D014079:Tooth Eruption, Ectopic / Q000209:etiology*; D014096:Tooth, Supernumerary / Q000209:etiology*
chemical_list: D013006:Growth Hormone