title: Immune response to Haemophilus influenzae type b vaccination in patients with chronic renal failure.
abstract: Adult chronic renal failure patients undergoing hemodialysis are at an increased risk of invasive Haemophilus influenzae type b (Hib) disease due to the lack of functionally active anti-Hib antibodies. The pediatric Hib polysaccharide-protein conjugate vaccine is highly immunogenic in these patients and can provide protection against invasive Hib infection for at least 1 year.
authors.affiliation: Northern Ontario School of Medicine, Lakehead University, Thunder Bay, Ontario, Canada.
authors.forename: Nicole
authors.initials: N
authors.lastname: Hawdon
authors.forename: Eli B
authors.initials: EB
authors.lastname: Nix
authors.forename: Raymond S W
authors.initials: RS
authors.lastname: Tsang
authors.forename: Garry
authors.initials: G
authors.lastname: Ferroni
authors.forename: William G
authors.initials: WG
authors.lastname: McCready
authors.forename: Marina
authors.initials: M
authors.lastname: Ulanova
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000907:Antibodies, Bacterial / Q000097:blood; D001770:Blood Bactericidal Activity; D005260:Female; D018073:Haemophilus Vaccines / Q000008:administration & dosage* / Q000276:immunology*; D019741:Haemophilus influenzae type b / Q000276:immunology*; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D007676:Kidney Failure, Chronic / Q000276:immunology* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis
chemical_list: D000907:Antibodies, Bacterial; D018073:Haemophilus Vaccines; D007074:Immunoglobulin G; D007075:Immunoglobulin M