title: Orally active peptidic bradykinin B1 receptor antagonists engineered from a cyclotide scaffold for inflammatory pain treatment.
authors.affiliation: School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, Singapore 637551, Singapore.
authors.forename: Clarence T T
authors.initials: CT
authors.lastname: Wong
authors.forename: Dewi K
authors.initials: DK
authors.lastname: Rowlands
authors.forename: Chi-Hang
authors.initials: CH
authors.lastname: Wong
authors.forename: Theodore W C
authors.initials: TW
authors.lastname: Lo
authors.forename: Giang K T
authors.initials: GK
authors.lastname: Nguyen
authors.forename: Hoi-Yeung
authors.initials: HY
authors.lastname: Li
authors.forename: James P
authors.initials: JP
authors.lastname: Tam
mesh_terms: D000284:Administration, Oral; D000595:Amino Acid Sequence; D000818:Animals; D017209:Apoptosis / Q000187:drug effects; D065169:Bradykinin B1 Receptor Antagonists; D047169:Cyclotides / Q000737:chemistry / Q000627:therapeutic use* / Q000633:toxicity; D006367:HeLa Cells; D006801:Humans; D051379:Mice; D018345:Mice, Knockout; D041681:NIH 3T3 Cells; D010146:Pain / Q000188:drug therapy*; D015202:Protein Engineering; D055550:Protein Stability; D043783:Receptor, Bradykinin B1 / Q000378:metabolism
chemical_list: D065169:Bradykinin B1 Receptor Antagonists; D047169:Cyclotides; D043783:Receptor, Bradykinin B1