title: [Influence of non-alcoholic fatty liver disease on cardiovascular disease].
abstract: Non-alcoholic fatty liver disease encompasses a spectrum ranging from simple steatosis to steatohepatitis without excess alcohol intake and is considered to be the hepatic manifestation of metabolic syndrome. Recent studies indicate that non-alcoholic fatty liver disease is closely related to cardiovascular disease, especially to thickening of the intima-media layer of the carotid artery, as the morphostructural manifestation of the presence of subclinical atheromatosis. Therefore, the correct management of non-alcoholic fatty liver disease would allow the natural history of both the liver disease and the atherosclerosis to be modified.
authors.affiliation: Unidad de Gestión Clínica de Enfermedades Digestivas, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas, Hospital Universitario de Valme, Universidad de Sevilla, Sevilla, España.
authors.forename: Javier
authors.initials: J
authors.lastname: Ampuero
authors.forename: Manuel
authors.initials: M
authors.lastname: Romero-Gómez
mesh_terms: D053305:Apolipoprotein C-III / Q000235:genetics; D050197:Atherosclerosis / Q000453:epidemiology* / Q000378:metabolism; D002318:Cardiovascular Diseases / Q000453:epidemiology* / Q000209:etiology / Q000378:metabolism / Q000517:prevention & control; D059168:Carotid Intima-Media Thickness; D008078:Cholesterol, LDL / Q000378:metabolism; D015897:Comorbidity; D003924:Diabetes Mellitus, Type 2 / Q000453:epidemiology; D050171:Dyslipidemias / Q000453:epidemiology / Q000378:metabolism; D005234:Fatty Liver / Q000453:epidemiology* / Q000235:genetics / Q000378:metabolism; D006801:Humans; D020138:Hyperhomocysteinemia / Q000453:epidemiology; D007333:Insulin Resistance; D008049:Lipase / Q000235:genetics; D008565:Membrane Proteins / Q000235:genetics; D024821:Metabolic Syndrome / Q000453:epidemiology* / Q000378:metabolism; D065626:Non-alcoholic Fatty Liver Disease; D009765:Obesity / Q000453:epidemiology; D012307:Risk Factors; D012907:Smoking / Q000009:adverse effects / Q000453:epidemiology; D014280:Triglycerides / Q000378:metabolism; D000217:Acyltransferases; D054512:Phospholipases A2, Calcium-Independent
chemical_list: D053305:Apolipoprotein C-III; D008078:Cholesterol, LDL; D008049:Lipase; D008565:Membrane Proteins; D014280:Triglycerides; C533682:PNPLA3 protein, human; D000217:Acyltransferases; D054512:Phospholipases A2, Calcium-Independent