title: Understanding the formation of CuS concave superstructures with peroxidase-like activity.
abstract: Copper sulfide (CuS) concave polyhedral superstructures (CPSs) have been successfully prepared in an ethanolic solution by a simple solvothermal reaction without the use of surfactants or templates. Two typical well defined, high symmetry CuS concave polyhedrons, forming a concave truncated cuboctahedron and icosahedron were prepared. The effect of the reaction time, temperature and different Cu ion and sulfur sources on the formation of CuS CPSs were investigated and a possible formation mechanism was proposed and discussed based on gas chromatography-mass spectrometry. More importantly, we found, for the first time, that the CuS CPSs exhibit intrinsic peroxidase-like activity, as they can quickly catalyze the oxidation of typical horseradish peroxidase (HRP) substrates, 3,3',5,5'-tetramethylbenzidine (TMB) and o-phenylenediamine (OPD), in the presence of hydrogen peroxide. In addition to the recent discoveries regarding peroxidase mimetics on Fe(3)O(4) NPs and carbon nanostructures, our findings suggest a new kind of candidate for peroxidase mimics. This may open up a new application field of CuS micro-nano structures in biodetection, biocatalysis and environmental monitoring.
authors.affiliation: Key Laboratory of Micro-Nano Materials for Energy Storage and Conversion of Henan Province, Institute of Surface Micro and Nano Materials, Xuchang University, Henan 461000, PR China.
authors.forename: Weiwei
authors.initials: W
authors.lastname: He
authors.forename: Huimin
authors.initials: H
authors.lastname: Jia
authors.forename: Xiaoxiao
authors.initials: X
authors.lastname: Li
authors.forename: Yan
authors.initials: Y
authors.lastname: Lei
authors.forename: Jing
authors.initials: J
authors.lastname: Li
authors.forename: Hongxiao
authors.initials: H
authors.lastname: Zhao
authors.forename: Liwei
authors.initials: L
authors.lastname: Mi
authors.forename: Lizhi
authors.initials: L
authors.lastname: Zhang
authors.forename: Zhi
authors.initials: Z
authors.lastname: Zheng
mesh_terms: D001560:Benzidines / Q000737:chemistry; D040761:Biomimetic Materials / Q000737:chemistry / Q000378:metabolism*; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D052203:Ferrosoferric Oxide / Q000737:chemistry; D006735:Horseradish Peroxidase / Q000737:chemistry / Q000378:metabolism; D006861:Hydrogen Peroxide / Q000737:chemistry; D053768:Metal Nanoparticles / Q000737:chemistry; D049329:Nanostructures / Q000737:chemistry*; D010084:Oxidation-Reduction; D009195:Peroxidase / Q000378:metabolism*
chemical_list: D001560:Benzidines; C021758:3,3',5,5'-tetramethylbenzidine; D003300:Copper; D006861:Hydrogen Peroxide; D006735:Horseradish Peroxidase; D009195:Peroxidase; C017846:cupric sulfide; D052203:Ferrosoferric Oxide