title: The preoperative assessment of deep myometrial invasion by three-dimensional ultrasound versus MRI in endometrial carcinoma.
abstract: OBJECTIVE
  To evaluate the usefulness of three-dimensional ultrasound (3D US), magnetic resonance imaging (MRI) and three-dimensional power Doppler angiography (3D-PDA) in the preoperative assessment of myometrial invasion in endometrial carcinoma.
  
  
  METHODS
  A prospective observational study.
  
  
  METHODS
  University hospital.
  
  
  METHODS
  Twenty consecutive patients diagnosed with endometrial carcinoma.
  
  
  METHODS
  Preoperative 3 T MRI and 3D US examinations were performed, and the depth of myometrial invasion was assessed. The vascularity indices, vascularization index, flow index and vascularization flow index, were calculated by 3D-PDA.
  
  
  METHODS
  The results were compared with the final histopathology report after a surgical staging.
  
  
  RESULTS
  In detecting deep myometrial invasion, the sensitivity of 3D US, MRI and their combination was 50, 91.7 and 100%, respectively. The specificity was 87.5, 50 and 50%, respectively. There were no significant differences in the 3D-PDA vascularity indices between the two groups.
  
  
  CONCLUSIONS
  MRI appears to be more sensitive than 3D US in detecting deep invasion, while 3D US has a better specificity.
authors.affiliation: Department of Obstetrics and Gynecology, Tampere University Hospital, Tampere, Finland.
authors.forename: Sami K
authors.initials: SK
authors.lastname: Saarelainen
authors.forename: Lea
authors.initials: L
authors.lastname: Kööbi
authors.forename: Ritva
authors.initials: R
authors.lastname: Järvenpää
authors.forename: Marita
authors.initials: M
authors.lastname: Laurila
authors.forename: Johanna U
authors.initials: JU
authors.lastname: Mäenpää
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000792:Angiography; D018269:Carcinoma, Endometrioid / Q000098:blood supply / Q000000981:diagnostic imaging* / Q000473:pathology* / Q000601:surgery; D016889:Endometrial Neoplasms / Q000098:blood supply / Q000000981:diagnostic imaging* / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D007044:Hysterectomy / Q000379:methods; D021621:Imaging, Three-Dimensional; D010535:Laparoscopy; D008197:Lymph Node Excision; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D009215:Myometrium / Q000098:blood supply / Q000000981:diagnostic imaging* / Q000473:pathology* / Q000601:surgery; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D011237:Predictive Value of Tests; D057234:Preoperative Period; D011446:Prospective Studies; D012680:Sensitivity and Specificity; D014463:Ultrasonography / Q000379:methods