title: Stereoselective synthesis of all stereoisomers of orthogonally protected cyclobutane-1,2-diamine and some chemoselective transformations.
abstract: The four stereoisomers of protected cyclobutane-1,2-diamine have been prepared in an enantio- and diastereocontrolled manner through stereodivergent synthetic routes starting from a half-ester as a common chiral precursor. Orthogonal protection allows the chemoselective manipulation of both amino groups as shown in this work.
authors.affiliation: Departament de Química, Universitat Autònoma de Barcelona , 08193 Cerdanyola del Vallès, Barcelona, Spain.
authors.forename: Marta
authors.initials: M
authors.lastname: Sans
authors.forename: Ona
authors.initials: O
authors.lastname: Illa
authors.forename: Rosa M
authors.initials: RM
authors.lastname: Ortuño
mesh_terms: D003503:Cyclobutanes / Q000138:chemical synthesis* / Q000737:chemistry; D003959:Diamines / Q000138:chemical synthesis* / Q000737:chemistry; D007202:Indicators and Reagents; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D003503:Cyclobutanes; D003959:Diamines; D007202:Indicators and Reagents