title: Preparation and chiral separation of a novel immobilized cellulose-based chiral stationary phase in high-performance liquid chromatography.
abstract: The chiral selector 6-azido-2, 3-di(p-chlorophenylcarbamoylated) cellulose was synthesized and further chemically immobilized onto 5-μm amino functionalized spherical porous silica gel. It was used as chiral stationary phase in high-performance liquid chromatography. Thirty racemates were successfully separated into enantiomers in either normal phase mode or reversed-phase mode. Good reproducibility and stability of the chiral stationary phase have been demonstrated.
authors.affiliation: School of Chemistry and Environment, South China Normal University, Guangzhou, 510006, China.
authors.forename: Gui Ming
authors.initials: GM
authors.lastname: Peng
authors.forename: Su Qin
authors.initials: SQ
authors.lastname: Wu
authors.forename: Zhi Li
authors.initials: ZL
authors.lastname: Fang
authors.forename: Wei Guang
authors.initials: WG
authors.lastname: Zhang
authors.forename: Zhen Bin
authors.initials: ZB
authors.lastname: Zhang
authors.forename: Jun
authors.initials: J
authors.lastname: Fan
authors.forename: Sheng Run
authors.initials: SR
authors.lastname: Zheng
authors.forename: Shang Sen
authors.initials: SS
authors.lastname: Wu
authors.forename: Siu Choon
authors.initials: SC
authors.lastname: Ng
mesh_terms: D002482:Cellulose / Q000737:chemistry*; D002851:Chromatography, High Pressure Liquid / Q000295:instrumentation* / Q000379:methods; D004364:Pharmaceutical Preparations / Q000737:chemistry*; D011108:Polymers / Q000138:chemical synthesis* / Q000737:chemistry; D058428:Silica Gel / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D004364:Pharmaceutical Preparations; D011108:Polymers; D058428:Silica Gel; D002482:Cellulose