title: Fatal reperfusion injury after thrombolysis for phlegmasia cerulea dolens.
abstract: Reperfusion injury after venous thrombolysis for phlegmasia cerulea dolens (PCD), despite its potentially rapid, fatal course, has not been well described in the literature. Two cases of fatal reperfusion injury after venous thrombolysis are reported, and the clinical manifestations and treatment strategies of PCD and the aspects of reperfusion injury relevant to the interventionalist are reviewed.
authors.affiliation: Division of Vascular and Interventional Radiology, Johns Hopkins School of Medicine, 600 North Wolfe Street, Blalock 545, Baltimore, MD 21287, USA. mlessne3@jhmi.edu
authors.forename: Mark L
authors.initials: ML
authors.lastname: Lessne
authors.forename: Jawad
authors.initials: J
authors.lastname: Bajwa
authors.forename: Kelvin
authors.initials: K
authors.lastname: Hong
mesh_terms: D000328:Adult; D000671:Amputation, Surgical; D015901:Angiography, Digital Subtraction; D057510:Endovascular Procedures; D017809:Fatal Outcome; D005260:Female; D005343:Fibrinolytic Agents / Q000009:adverse effects*; D005734:Gangrene; D006801:Humans; D008875:Middle Aged; D010690:Phlebography / Q000379:methods; D015427:Reperfusion Injury / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D015912:Thrombolytic Therapy / Q000009:adverse effects*; D013924:Thrombophlebitis / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology; D018615:Ultrasonography, Doppler, Color; D020246:Venous Thrombosis / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*
chemical_list: D005343:Fibrinolytic Agents