title: H1N1-associated acute retinitis.
abstract: OBJECTIVE
  To present the first reported case of bilateral H(1)N(1)-associated acute retinitis and its successful treatment.
  
  
  METHODS
  Interventional case report.
  
  
  METHODS
  A 41-year-old HIV-positive male presented with acute vision loss, panuveitis, and retinitis. A diagnostic and therapeutic vitrectomy with intravitreal injection of vancomycin and ganciclovir and endolaser was performed. One month later, the patient returned with similar symptoms in the fellow eye and underwent the same procedure.
  
  
  RESULTS
  ELISA immunoassay revealed H(1)N(1) antibodies in both the vitreous and serum. PCR for herpes viruses included HSV, CMV, and VZV. Bacterial and fungal cultures were negative. On 1-year follow-up, the vision remained 20/20 in both eyes without evidence of recurrent inflammation.
  
  
  CONCLUSIONS
  H(1)N(1) should be included in the differential diagnosis of any patient with a history of recent influenza A (H(1)N(1)) infection and acute retinitis. H(1)N(1) may carry a better prognosis than other viruses causing acute retinitis.
authors.forename: Lana
authors.initials: L
authors.lastname: Rifkin
authors.forename: Shlomit
authors.initials: S
authors.lastname: Schaal
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis / Q000188:drug therapy / Q000821:virology*; D000208:Acute Disease; D000328:Adult; D015828:Eye Infections, Viral / Q000175:diagnosis / Q000188:drug therapy / Q000628:therapy / Q000821:virology*; D015774:Ganciclovir / Q000627:therapeutic use; D006679:HIV Seropositivity / Q000150:complications*; D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype / Q000187:drug effects / Q000302:isolation & purification*; D007251:Influenza, Human / Q000175:diagnosis / Q000188:drug therapy / Q000821:virology*; D053685:Laser Therapy; D008297:Male; D012173:Retinitis / Q000175:diagnosis / Q000188:drug therapy / Q000628:therapy / Q000821:virology*; D016896:Treatment Outcome; D014640:Vancomycin / Q000627:therapeutic use
chemical_list: D014640:Vancomycin; D015774:Ganciclovir