title: Cytokine expression profiles associated with distinct clinical courses in hepatitis A virus-infected children.
abstract: We determined the serum cytokine profiles during distinct hepatitis A virus-induced clinical courses in children. A significant overexpression of interleukin-1, interleukin-6, tumor necrosis factor-alpha and monocyte chemotactic protein-2 was found in children with intermediate liver injury, whereas the patients with minor liver injury had a significant increase of interleukin-8 and transforming growth factor-beta values.
authors.affiliation: Unidad de Inmunovirologia, Hospital Civil of Guadalajara "Fray Antonio Alcalde," Guadalajara, Jalisco, Mexico.
authors.forename: Nora A
authors.initials: NA
authors.lastname: Fierro
authors.forename: Griselda
authors.initials: G
authors.lastname: Escobedo-Melendez
authors.forename: Lisbeth
authors.initials: L
authors.lastname: De Paz
authors.forename: Mauricio
authors.initials: M
authors.lastname: Realpe
authors.forename: Sonia
authors.initials: S
authors.lastname: Roman
authors.forename: Arturo
authors.initials: A
authors.lastname: Panduro
mesh_terms: D000293:Adolescent; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D016207:Cytokines / Q000097:blood* / Q000276:immunology; D018450:Disease Progression; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006506:Hepatitis A / Q000097:blood* / Q000276:immunology; D006801:Humans; D015151:Immunoblotting; D007223:Infant; D008297:Male
chemical_list: D016207:Cytokines