title: Association study of copy number variants with brain volume in schizophrenia patients and healthy controls.
abstract: Schizophrenia patients have more copy number variations (CNVs) than healthy controls, and reduced brain volumes. Although this could suggest a causal relationship, we found no association between global CNV burden and three brain volume measures (on a MRI scan) in a sample of 173 schizophrenia patients and 176 healthy controls.
authors.affiliation: Department of Psychiatry, Rudolf Magnus Institute of Neuroscience, University Medical Centre Utrecht, Huispostnummer A00.241, Heidelberglaan 100, 3584 CX, Utrecht, the Netherlands. aterwiss@umcutrecht.nl
authors.forename: Afke
authors.initials: A
authors.lastname: Terwisscha van Scheltinga
authors.forename: Steven
authors.initials: S
authors.lastname: Bakker
authors.forename: Neeltje
authors.initials: N
authors.lastname: van Haren
authors.forename: Jacobine
authors.initials: J
authors.lastname: Buizer-Voskamp
authors.forename: Heleen
authors.initials: H
authors.lastname: Boos
authors.forename: Jacob
authors.initials: J
authors.lastname: Vorstman
authors.forename: Wiepke
authors.initials: W
authors.lastname: Cahn
authors.forename: Hilleke
authors.initials: H
authors.lastname: Hulshoff Pol
authors.forename: Roel
authors.initials: R
authors.lastname: Ophoff
authors.forename: René
authors.initials: R
authors.lastname: Kahn
mesh_terms: D000328:Adult; D001921:Brain / Q000473:pathology*; D056915:DNA Copy Number Variations; D005260:Female; D020022:Genetic Predisposition to Disease; D005838:Genotype; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009929:Organ Size / Q000235:genetics; D012559:Schizophrenia / Q000235:genetics* / Q000473:pathology*