title: [New treatment strategies for intraventricular hemorrhage].
abstract: The presence of additional intraventricular hemorrhage (IVH) in patients with intracerebral hemorrhage (ICH) is associated with a much higher mortality and worse functional outcome. Although evidence-based specific treatment options for this entity are still lacking, knowledge about the pathophysiology of IVH has grown in recent decades, leading to the development of promising treatment strategies. Intraventricular fibrinolysis (IVF) accelerates IVH resolution and removal from the ventricular system. The additional usage of lumbar drains probably reduces the incidence of permanent posthemorrhagic hydrocephalus. The influence of these treatment modalities on functional outcome is currently being investigated in ongoing studies. The present article gives an overview of pathophysiological and clinical aspects of IVH, emphasizing novel treatment options.
authors.affiliation: Neurologische Klinik, Universitätsklinikum Erlangen, Schwabachanlage 6, 91054, Erlangen, Deutschland. dimitre.staykov@uk-erlangen.de
authors.forename: D
authors.initials: D
authors.lastname: Staykov
authors.forename: H B
authors.initials: HB
authors.lastname: Huttner
authors.forename: S
authors.initials: S
authors.lastname: Schwab
mesh_terms: D002543:Cerebral Hemorrhage / Q000145:classification / Q000401:mortality / Q000503:physiopathology / Q000628:therapy*; D002552:Cerebral Ventricles / Q000503:physiopathology; D003422:Critical Care / Q000379:methods*; D004322:Drainage / Q000379:methods; D019317:Evidence-Based Medicine; D006801:Humans; D006849:Hydrocephalus / Q000145:classification / Q000401:mortality / Q000503:physiopathology / Q000517:prevention & control / Q000628:therapy; D007427:Intracranial Pressure / Q000502:physiology; D011379:Prognosis; D016032:Randomized Controlled Trials as Topic; D013129:Spinal Puncture; D015996:Survival Rate; D015912:Thrombolytic Therapy / Q000379:methods; D010959:Tissue Plasminogen Activator / Q000627:therapeutic use; D014057:Tomography, X-Ray Computed; D017287:Ventriculoperitoneal Shunt
chemical_list: D010959:Tissue Plasminogen Activator