title: C-peptide: a new mediator of atherosclerosis in diabetes.
abstract: Diabetes type 2 and insulin resistance are the risk factors for cardiovascular disease. It is already known that atherosclerosis is an inflammatory disease, and a lot of different factors are involved in its onset. C-peptide is a cleavage product of proinsulin, an active substance with a number of effects within different complications of diabetes. In this paper we discuss the role of C-peptide and its effects in the development of atherosclerosis in type 2 diabetic patients.
authors.affiliation: Department of Internal Medicine II-Cardiology, University of Ulm, Albert-Einstein-Allee 11, 89081 Ulm, Germany.
authors.forename: Dusica
authors.initials: D
authors.lastname: Vasic
authors.forename: Daniel
authors.initials: D
authors.lastname: Walcher
mesh_terms: D000818:Animals; D050197:Atherosclerosis / Q000097:blood* / Q000150:complications*; D002096:C-Peptide / Q000097:blood*; D048909:Diabetes Complications / Q000097:blood* / Q000175:diagnosis; D003920:Diabetes Mellitus / Q000097:blood*; D006801:Humans; D007249:Inflammation; D007328:Insulin / Q000378:metabolism; D007333:Insulin Resistance; D008954:Models, Biological; D011384:Proinsulin / Q000378:metabolism; D015398:Signal Transduction
chemical_list: D002096:C-Peptide; D007328:Insulin; D011384:Proinsulin