title: Two-step asymmetric reaction using the frozen chirality generated by spontaneous crystallization.
abstract: N,N-diallyl-4-methyl-1-propyl-2-quinolone-3-carboxamide afforded chiral crystals of a P2(1) crystal system by spontaneous crystallization. The molecular chirality in the crystal was retained after the crystals were dissolved in a solvent at a low temperature, and the frozen molecular chirality was effectively transferred to the products by a two-step reaction involving hydrogenation and intermolecular photocycloaddition reactions.
authors.affiliation: Department of Applied Chemistry and Biotechnology, Graduate School of Engineering, Chiba University , Yayoi-cho, Inage-ku, Chiba 263-8522, Japan.
authors.forename: Fumitoshi
authors.initials: F
authors.lastname: Yagishita
authors.forename: Takashi
authors.initials: T
authors.lastname: Mino
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Fujita
authors.forename: Masami
authors.initials: M
authors.lastname: Sakamoto