title: Anti-Inflammatory, Analgesic, and Antipyretic Activities of the Ethanol Extract of Piper interruptum Opiz. and Piper chaba Linn.
abstract: Piper interruptum Opiz. and Piper chaba Linn. are herbaceous plants in the Piperaceae family. The ethanol extract of P. interruptum and P. chaba inhibited ethyl phenylpropiolate-induced ear edema and carrageenan-induced hind paw edema in rats. Both extracts reduced transudative and granuloma weights as well as body weight gain and thymus weight of the chronic inflammatory model using cotton pellet-induced granuloma formation in rats. Moreover, both extracts exhibited analgesic activity on both early phase and late phase of formalin test in mice and also showed antipyretic activity on yeast-induced hyperthermia in rats.
authors.affiliation: Division of Pharmacology, Department of Preclinical Science, Faculty of Medicine, Thammasat University, Pathumthani 12120, Thailand.
authors.forename: Seewaboon
authors.initials: S
authors.lastname: Sireeratawong
authors.forename: Arunporn
authors.initials: A
authors.lastname: Itharat
authors.forename: Nusiri
authors.initials: N
authors.lastname: Lerdvuthisopon
authors.forename: Pritsana
authors.initials: P
authors.lastname: Piyabhan
authors.forename: Parirat
authors.initials: P
authors.lastname: Khonsung
authors.forename: Supot
authors.initials: S
authors.lastname: Boonraeng
authors.forename: Kanjana
authors.initials: K
authors.lastname: Jaijoy