title: Jacobsen protocols for large-scale epoxidation of cyclic dienyl sulfones: application to the (+)-pretazettine core.
abstract: A Jacobsen epoxidation protocol using H2O2 as oxidant was designed for the large-scale preparation of various epoxy vinyl sulfones. A number of cocatalysts were screened, and pH control led to increased reaction rate, higher turnover number, and improved reliability.
authors.affiliation: Department of Chemistry, Purdue University , West Lafayette, Indiana 47906, United States.
authors.forename: G Reza
authors.initials: GR
authors.lastname: Ebrahimian
authors.forename: Xavier Mollat
authors.initials: XM
authors.lastname: du Jourdin
authors.forename: Philip L
authors.initials: PL
authors.lastname: Fuchs