title: Alkenenitrile Transmissive Olefination: Synthesis of the Putative Lignan "Morinol I"
abstract: Grignard reagents trigger an addition-elimination with α'-hydroxy acrylonitriles to selectively generate Z-alkenenitriles. The modular assembly of Z-alkenenitriles from a Grignard reagent, acrylonitrile, and an aldehyde is ideal for stereoselectively synthesizing alkenes as illustrated in the synthesis of the putative lignan "morinol I."
authors.affiliation: Department of Chemistry and Biochemistry, Duquesne University, Pittsburgh, PA 15282-1530, USA.
authors.forename: Fraser F
authors.initials: FF
authors.lastname: Fleming
authors.forename: Wang
authors.initials: W
authors.lastname: Liu
authors.forename: Lihua
authors.initials: L
authors.lastname: Yao
authors.forename: Bhaskar
authors.initials: B
authors.lastname: Pitta
authors.forename: Matthew
authors.initials: M
authors.lastname: Purzycki
authors.forename: P C
authors.initials: PC
authors.lastname: Ravikumar