title: Unilateral hydronephrosis and renal damage after acute leukemia.
abstract: A 14-year-old boy presented with asymptomatic right hydronephrosis detected on routine yearly ultrasound examination. Previously, he had at least two normal renal ultrasonograms, 4 years after remission of acute myeloblastic leukemia, treated by AML-BFM-93 protocol. A function of the right kidney and no damage on the left was confirmed by a DMSA scan. Right retroperitoneoscopic nephrectomy revealed 3 renal arteries with the lower pole artery lying on the pelviureteric junction. Histologically chronic tubulointerstitial nephritis was detected. In the pathogenesis of this severe unilateral renal damage, we suspect the exacerbation of deleterious effects of cytostatic therapy on kidneys with intermittent hydronephrosis.
authors.affiliation: Children's Hospital, Vilnius University Hospital Santariskiu Klinikos, Santariskiu Street 7, 08406 Vilnius, Lithuania.
authors.forename: Egle
authors.initials: E
authors.lastname: Simanauskiene
authors.forename: Valentina
authors.initials: V
authors.lastname: Daugelaviciene
authors.forename: Arvydas
authors.initials: A
authors.lastname: Laurinavicius
authors.forename: Ugnius
authors.initials: U
authors.lastname: Mickys
authors.forename: Vaida
authors.initials: V
authors.lastname: Simonyte
authors.forename: Goda
authors.initials: G
authors.lastname: Vaitkeviciene
authors.forename: Gilvydas
authors.initials: G
authors.lastname: Verkauskas