title: Clinical syndromes and management of intracerebral hemorrhage.
abstract: Spontaneous intracerebral hemorrhage (ICH) is a devastating disease with high morbidity and mortality. Acutely, ICH is associated with a sudden surge in intracranial pressure (ICP), as the volume of hematoma increases the pressure in the closed head, leading to non-specific symptoms of ICP: headache, nausea, vomiting, and alterations in consciousness. In the early phase, damage to the brain tissues surrounding the hematoma causes progression of neurologic symptoms. Expansion of supratentorial ICHs may result in transtentorial herniation, causing mental status deterioration and loss of pupillary light reflex. Compared to ischemic stroke, seizure is more common in ICH.
authors.affiliation: Department of Neurology, Seoul National University Hospital, Korea.
authors.forename: Sang-Bae
authors.initials: SB
authors.lastname: Ko
authors.forename: H Alex
authors.initials: HA
authors.lastname: Choi
authors.forename: Kiwon
authors.initials: K
authors.lastname: Lee
mesh_terms: D016657:Cerebral Amyloid Angiopathy / Q000150:complications; D002543:Cerebral Hemorrhage / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy; D003029:Coagulants / Q000627:therapeutic use*; D003399:Craniotomy / Q000379:methods; D005167:Factor VII / Q000627:therapeutic use*; D006406:Hematoma / Q000150:complications; D006801:Humans; D006973:Hypertension / Q000150:complications*; D020299:Intracranial Hemorrhage, Hypertensive / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy; D012640:Seizures / Q000209:etiology; D013566:Sympathomimetics / Q000009:adverse effects
chemical_list: D003029:Coagulants; D013566:Sympathomimetics; D005167:Factor VII