title: Current knowledge on regulatory RNAs and their machineries in Staphylococcus aureus.
abstract: Staphylococcus aureus is one of the major human pathogens, which causes numerous community-associated and hospital-acquired infections. The regulation of the expression of numerous virulence factors is coordinated by complex interplays between two component systems, transcriptional regulatory proteins, and regulatory RNAs. Recent studies have identified numerous novel RNAs comprising cis-acting regulatory RNAs, antisense RNAs, small non coding RNAs and small mRNAs encoding peptides. We present here several examples of RNAs regulating S. aureus pathogenicity and describe various aspects of antisense regulation.
authors.affiliation: Architecture et Réactivité de l'ARN, Université de Strasbourg, CNRS, IBMC, Strasbourg, France.
authors.forename: Cédric
authors.initials: C
authors.lastname: Romilly
authors.forename: Isabelle
authors.initials: I
authors.lastname: Caldelari
authors.forename: Delphine
authors.initials: D
authors.lastname: Parmentier
authors.forename: Efthimia
authors.initials: E
authors.lastname: Lioliou
authors.forename: Pascale
authors.initials: P
authors.lastname: Romby
authors.forename: Pierre
authors.initials: P
authors.lastname: Fechter
mesh_terms: D000818:Animals; D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism; D015964:Gene Expression Regulation, Bacterial; D006801:Humans; D053038:Quorum Sensing; D034622:RNA Interference; D012329:RNA, Bacterial / Q000235:genetics* / Q000502:physiology; D058727:RNA, Small Untranslated / Q000235:genetics* / Q000502:physiology; D013211:Staphylococcus aureus / Q000235:genetics* / Q000254:growth & development / Q000472:pathogenicity; D014774:Virulence / Q000235:genetics
chemical_list: D001426:Bacterial Proteins; D012329:RNA, Bacterial; D058727:RNA, Small Untranslated