title: In silico experimental modeling of cancer treatment.
abstract: In silico experimental modeling of cancer involves combining findings from biological literature with computer-based models of biological systems in order to conduct investigations of hypotheses entirely in the computer laboratory. In this paper, we discuss the use of in silico modeling as a precursor to traditional clinical and laboratory research, allowing researchers to refine their experimental programs with an aim to reducing costs and increasing research efficiency. We explain the methodology of in silico experimental trials before providing an example of in silico modeling from the biomathematical literature with a view to promoting more widespread use and understanding of this research strategy.
authors.affiliation: Mathematical Sciences Discipline, Queensland University of Technology, P.O. Box 2434, Brisbane, QLD 4001, Australia.
authors.lastname: Trisilowati
authors.forename: D G
authors.initials: DG
authors.lastname: Mallet