title: Combining cohort analysis and monitoring of HIV early-warning indicators of drug resistance to assess antiretroviral therapy services in Vietnam.
abstract: Antiretroviral therapy (ART) retention and 5 early-warning indicators (EWIs) of HIV drug resistance (HIVDR) were abstracted at 27 adult and 4 pediatric clinics in Vietnam in 2009. Of 4531 adults and 313 children, 81.2% and 84.4% respectively were still on ART at 12 months. More than 90% of the clinics monitored achieved the World Health Organization (WHO) targets for lost-to-follow-up (LTFU), ART prescribing practices, and ARV supply continuity. Only 83.9% of the clinics met the target for first-line ART retention and 79.3% met the target for clinic appointment-keeping. Clinic factors (i.e. number of patients, administrative level, and geographical region) were associated with ART retention and LFTU. Data were useful in guiding public health action to optimize ART services.
authors.affiliation: Vietnam Authority of HIV/AIDS Control, Ministry of Health, Hanoi, Vietnam.
authors.forename: Thi Nhan
authors.initials: TN
authors.lastname: Do
authors.forename: Thi Minh Thu
authors.initials: TM
authors.lastname: Nguyen
authors.forename: Mai Hoa
authors.initials: MH
authors.lastname: Do
authors.forename: Kato
authors.initials: K
authors.lastname: Masaya
authors.forename: Thi Bich
authors.initials: TB
authors.lastname: Dang
authors.forename: Thuy Linh
authors.initials: TL
authors.lastname: Pham
authors.forename: Kayoko
authors.initials: K
authors.lastname: Yoshikawa
authors.forename: Thi Than Thuy
authors.initials: TT
authors.lastname: Cao
authors.forename: Thi Thuy Van
authors.initials: TT
authors.lastname: Nguyen
authors.forename: Duc Duong
authors.initials: DD
authors.lastname: Bui
authors.forename: Van Kinh
authors.initials: VK
authors.lastname: Nguyen
authors.forename: Thanh Long
authors.initials: TL
authors.lastname: Nguyen
authors.forename: Masami
authors.initials: M
authors.lastname: Fujita
mesh_terms: D000328:Adult; D000554:Ambulatory Care Facilities / Q000706:statistics & numerical data; D044966:Anti-Retroviral Agents / Q000494:pharmacology* / Q000600:supply & distribution / Q000627:therapeutic use; D002648:Child; D015331:Cohort Studies; D024882:Drug Resistance, Viral; D015658:HIV Infections / Q000188:drug therapy* / Q000453:epidemiology*; D006801:Humans; D059012:Lost to Follow-Up; D009313:National Health Programs; D016017:Odds Ratio; D010349:Patient Compliance / Q000706:statistics & numerical data; D011159:Population Surveillance; D014744:Vietnam / Q000453:epidemiology; D014944:World Health Organization
chemical_list: D044966:Anti-Retroviral Agents