title: An unusual regression of the symptoms of Kartagener syndrome.
abstract: Kartagener's syndrome is a rare autosomal-recessive genetic disease with progressive damage of the respiratory system and situs inversus. Although the management of patients with Kartagener's syndrome remains uncertain and evidence is limited, it is important to follow up these patients with an adequate and shared care system. This report presents a clinical case of Kartagener's syndrome in a 25-year-old woman. Computed tomography showed dextrocardia and bronchiectasis. Abdominal X-ray and ultrasound confirmed situs inversus totalis. After 7 years, good treatment results were achieved: lung function improved and radiological findings showed no changes. The present case discusses the complex interrelationship between the genetic variation and a proper nonspecific management of Kartagener's syndrome.
authors.affiliation: Department of Pulmonology and Immunology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lituania. dserapinas@gmail.com
authors.forename: Danielius
authors.initials: D
authors.lastname: Serapinas
authors.forename: Jūratė
authors.initials: J
authors.lastname: Staikūnienė
authors.forename: Diana
authors.initials: D
authors.lastname: Barkauskienė
authors.forename: Jurgita
authors.initials: J
authors.lastname: Jackutė
authors.forename: Raimundas
authors.initials: R
authors.lastname: Sakalauskas
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001987:Bronchiectasis / Q000000981:diagnostic imaging / Q000209:etiology; D001993:Bronchodilator Agents / Q000627:therapeutic use; D002352:Carrier Proteins / Q000235:genetics / Q000502:physiology; D003131:Combined Modality Therapy; D018450:Disease Progression; D004198:Disease Susceptibility; D005100:Expectorants / Q000627:therapeutic use; D005260:Female; D005838:Genotype; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis; D007619:Kartagener Syndrome / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000235:genetics / Q000503:physiopathology* / Q000628:therapy; D012138:Respiratory Therapy; D012141:Respiratory Tract Infections / Q000188:drug therapy / Q000209:etiology; D013147:Spirometry; D014057:Tomography, X-Ray Computed
chemical_list: D000900:Anti-Bacterial Agents; D001993:Bronchodilator Agents; C470011:CFAP91 protein, human; D002352:Carrier Proteins; D005100:Expectorants; D007070:Immunoglobulin A