title: Lateralized petrous internal carotid artery: imaging features and distinction from the aberrant internal carotid artery.
abstract: BACKGROUND
  This study aimed to describe the lateralized petrous internal carotid artery (ICA), a rare variant of the intratemporal course of the ICA, and distinguish it from aberrant ICA.
  
  
  METHODS
  A retrospective multi-institutional review of all patients diagnosed over a 10-year period with lateralized ICA was completed. Medical records were reviewed for demographic data as well as clinical information in all patients. Computerized tomography (CT) studies were reviewed in all patients. Magnetic resonance studies in this patient group were reviewed when available. In order to obtain normative data for the ICA, the intratemporal course of the ICA was evaluated on 50 consecutive high-resolution sinus CT scans.
  
  
  RESULTS
  Sixteen cases of lateralized ICA were identified on CT scans in 12 patients. In each of these, the ICA entered the skull base in a position more lateral to the cochlea than normal and protruded into the anterior mesotympanum with dehiscent or thinned overlying bone. Magnetic resonance angiography was available in 5 of 12 patients and catheter angiography in 1 of 12.
  
  
  CONCLUSIONS
  Lateralized petrous ICA can be identified on CT by its more posterolateral entrance to the skull base and protrusion into the anterior mesotympanum. It can be distinguished from the aberrant ICA which enters the posterior hypotympanum through an enlarged inferior tympanic canaliculus, then courses across the inferior cochlear promontory to connect with the normal horizontal petrous ICA. Lateralized ICA is best considered an incidental petrous ICA variant. Awareness of this entity is important in the presurgical evaluation of the temporal bone to avoid vascular injury and confusion with the congenital diagnosis of aberrant ICA.
authors.affiliation: Neuroradiology Section, Department of Radiology, University of California, San Francisco, CA, USA.
authors.forename: Christine M
authors.initials: CM
authors.lastname: Glastonbury
authors.forename: H Ric
authors.initials: HR
authors.lastname: Harnsberger
authors.forename: Patricia A
authors.initials: PA
authors.lastname: Hudgins
authors.forename: Karen L
authors.initials: KL
authors.lastname: Salzman
mesh_terms: D000328:Adult; D000368:Aged; D002343:Carotid Artery, Internal / Q000002:abnormalities* / Q000000981:diagnostic imaging*; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D010579:Petrous Bone / Q000000981:diagnostic imaging; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed