title: Regulatory long non-coding RNA and its functions.
abstract: The discovery of large numbers of long non-coding RNAs (lncRNAs) has been driven by genome-wide transcriptional analyses. Compared to small ncRNAs, lncRNAs have been shown to harbor biological activities, but the functions of the great majority of lncRNAs are not known. There is growing evidence that lncRNAs can regulate gene expression at epigenetic, transcription, and post-transcription levels and widely take part in various physiological and pathological processes, such as participating in cell development, immunity, oncogenesis, clinical disease processes, etc. Here, the current research efforts on the function of lncRNA in recent years were summarized.
authors.affiliation: Animal Science and Technology College, He Nan University of Science and Technology, Luoyang City 471003, Henan Province, People's Republic of China.
authors.forename: Yong
authors.initials: Y
authors.lastname: Huang
authors.forename: Ning
authors.initials: N
authors.lastname: Liu
authors.forename: Jian Ping
authors.initials: JP
authors.lastname: Wang
authors.forename: Yu Qin
authors.initials: YQ
authors.lastname: Wang
authors.forename: Xue Li
authors.initials: XL
authors.lastname: Yu
authors.forename: Zhan Bin
authors.initials: ZB
authors.lastname: Wang
authors.forename: Xiang Chao
authors.initials: XC
authors.lastname: Cheng
authors.forename: Quan
authors.initials: Q
authors.lastname: Zou
mesh_terms: D000818:Animals; D044127:Epigenesis, Genetic; D015972:Gene Expression Regulation, Neoplastic; D006801:Humans; D007113:Immunity, Innate; D009369:Neoplasms / Q000235:genetics / Q000378:metabolism; D062085:RNA, Long Noncoding / Q000235:genetics / Q000378:metabolism / Q000502:physiology*; D013234:Stem Cells / Q000502:physiology; D014158:Transcription, Genetic
chemical_list: D062085:RNA, Long Noncoding