title: Positively charged silver nanoparticles and their effect on surface-enhanced Raman scattering of dye-labelled oligonucleotides.
abstract: Improved positively charged nanoparticles are described to provide a simplified SERS substrate for DNA detection. Complete flocculation of the nanoparticles is prevented due to the controlled analyte induced aggregation. This provides a stable aggregation state which significantly extends the analysis window simplifying DNA detection by SERS.
authors.affiliation: Centre for Molecular Nanometrology, WestCHEM, Department of Pure and Applied Chemistry, University of Strathclyde, 295 Cathedral St., Glasgow, G1 1XL, UK.
authors.forename: Danny
authors.initials: D
authors.lastname: van Lierop
authors.forename: Željka
authors.initials: Ž
authors.lastname: Krpetić
authors.forename: Luca
authors.initials: L
authors.lastname: Guerrini
authors.forename: Iain A
authors.initials: IA
authors.lastname: Larmour
authors.forename: Jennifer A
authors.initials: JA
authors.lastname: Dougan
authors.forename: Karen
authors.initials: K
authors.lastname: Faulds
authors.forename: Duncan
authors.initials: D
authors.lastname: Graham
mesh_terms: D004396:Coloring Agents / Q000737:chemistry*; D053768:Metal Nanoparticles / Q000737:chemistry*; D009841:Oligonucleotides / Q000737:chemistry*; D012834:Silver / Q000737:chemistry*; D013059:Spectrum Analysis, Raman; D013096:Spermine / Q000737:chemistry; D013499:Surface Properties
chemical_list: D004396:Coloring Agents; D009841:Oligonucleotides; D013096:Spermine; D012834:Silver