title: Successful childbearing in two women with rheumatoid arthritis and a history of miscarriage after etanercept treatment.
abstract: Two women with rheumatoid arthritis who had experienced miscarriages became pregnant while they were under etanercept treatment. One stopped etanercept after 3 weeks with increased doses of prednisolone, and the other restarted etanercept at a half doses 3 months later. They delivered a healthy baby at full term, and no problems in both expecting mothers and babies were observed. The use of etanercept in patients with rheumatoid arthritis seemed safe for pregnant mothers and their fetuses.
authors.affiliation: Department of Internal Medicine, Nihon University Nerima-Hikarigaoka Hospital, Tokyo, Japan.
authors.forename: Ikumi
authors.initials: I
authors.lastname: Natsumi
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Matsukawa
authors.forename: Kohji
authors.initials: K
authors.lastname: Miyagawa
authors.forename: Hitomi
authors.initials: H
authors.lastname: Kodaira
authors.forename: Toshitake
authors.initials: T
authors.lastname: Tanaka
authors.forename: Akira
authors.initials: A
authors.lastname: Horikoshi
authors.forename: Jin
authors.initials: J
authors.lastname: Takeuchi
authors.forename: Masami
authors.initials: M
authors.lastname: Takei
authors.forename: Mamoru
authors.initials: M
authors.lastname: Maejima
authors.forename: Jun
authors.initials: J
authors.lastname: Akimoto
mesh_terms: D000328:Adult; D018501:Antirheumatic Agents / Q000627:therapeutic use*; D001172:Arthritis, Rheumatoid / Q000188:drug therapy*; D000068800:Etanercept; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000627:therapeutic use*; D007231:Infant, Newborn; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy*; D018124:Receptors, Tumor Necrosis Factor / Q000627:therapeutic use*; D014409:Tumor Necrosis Factor-alpha / Q000037:antagonists & inhibitors*
chemical_list: D018501:Antirheumatic Agents; D007074:Immunoglobulin G; D018124:Receptors, Tumor Necrosis Factor; D014409:Tumor Necrosis Factor-alpha; D000068800:Etanercept