title: Primary diffuse large B cell lymphoma of the base of tongue.
abstract: Primary non-Hodgkin's lymphoma of tongue is very rare. We report a case of an elderly female who presented with a mass lesion and pain primarily involving the tongue and was diagnosed with diffuse large B cell lymphoma. Computed tomography revealed a 3-cm enhanced mass localized to the right tongue base. The patient was treated with three cycles of combination rituximab and CHOP chemotherapy, followed by external beam radiotherapy. The patient had a complete response after treatment, and three years following treatment, the patient has no signs of recurrence.
authors.affiliation: Department of Internal Medicine, Inha University School of Medicine, Incheon, Korea.
authors.forename: Joo Han
authors.initials: JH
authors.lastname: Lim
authors.forename: Jae-Yol
authors.initials: JY
authors.lastname: Lim
authors.forename: Young Mo
authors.initials: YM
authors.lastname: Kim
authors.forename: Chul Soo
authors.initials: CS
authors.lastname: Kim
authors.forename: Suk Jin
authors.initials: SJ
authors.lastname: Choi
authors.forename: Hyeon Gyu
authors.initials: HG
authors.lastname: Yi
authors.forename: Woong Gil
authors.initials: WG
authors.lastname: Choi
authors.forename: Moon Hee
authors.initials: MH
authors.lastname: Lee
mesh_terms: D000368:Aged; D058846:Antibodies, Monoclonal, Murine-Derived; D000971:Antineoplastic Combined Chemotherapy Protocols; D003520:Cyclophosphamide; D004317:Doxorubicin; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007150:Immunohistochemistry; D016403:Lymphoma, Large B-Cell, Diffuse / Q000175:diagnosis* / Q000188:drug therapy / Q000532:radiotherapy; D064847:Multimodal Imaging; D049268:Positron-Emission Tomography; D011241:Prednisone; D000069283:Rituximab; D014057:Tomography, X-Ray Computed; D014062:Tongue Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000532:radiotherapy; D016896:Treatment Outcome; D014750:Vincristine
chemical_list: D058846:Antibodies, Monoclonal, Murine-Derived; C571759:R-CHOP protocol; D000069283:Rituximab; D014750:Vincristine; D004317:Doxorubicin; D003520:Cyclophosphamide; D011241:Prednisone