title: [Comparison of endobronchial ultrasound (EBUS) and mediastinoscopy (MS) for staging lung cancer].
abstract: Diagnostic findings of mediastinal metastasis are an important factor for the prognosis of and therapy for lung cancer. In this retrospective study we examined the role of endobronchial ultrasound with transbronchial needle aspiration (EBUS) and mediastinoscopy (MS) in patients with confirmed lung cancer. Between 01/2009 and 07/2011 we performed 111 EBUS procedures [partly in combination with transoesophageal endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA)] and 88 mediastinoscopies. The diagnostic accuracy of EBUS (94%) was superior to that of MS (86%) (p < 0.05). The negative predictive value of EBUS and MS was 83% for both, the sensitivity was 94% vs. 58%, the prevalence of N2 /N3 was 84% vs. 32% and the rate of complications was 0% vs. 3%. Due to the at least similar accuracy the EBUS should be the first diagnostic procedure for histological staging of the mediastinum in patients with lung cancer.
authors.affiliation: Lungenzentrum Bethanien Moers, Abteilung für Pneumologie, Allergologie, Zentrum für Schlaf- und Beatmungsmedizin. kambartel@bethanienmoers.de
authors.forename: K
authors.initials: K
authors.lastname: Kambartel
authors.forename: T
authors.initials: T
authors.lastname: Krbek
authors.forename: T
authors.initials: T
authors.lastname: Voshaar
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D019160:Endosonography / Q000379:methods*; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology*; D008297:Male; D008481:Mediastinoscopy / Q000379:methods*; D008875:Middle Aged; D009367:Neoplasm Staging; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity