title: Toxic Epidermal Necrolysis induced by rarely implicated drugs.
abstract: Toxic Epidermal Necrolysis (TEN) and Steven-Johnson Syndrome (SJS) are serious disorders commonly caused as idiosyncratic reactions to drugs, the most common ones being oxicams, anticonvulsants, allopurinol, and sulfonamides. We present a case of TEN in a patient who developed the lesions after ingesting multiple drugs including paracetamol, metoclopramide, antihistamines, and multivitamins. These drugs have rarely been implicated in this disorder. The suspected drugs in this case were paracetamol and metoclopramide. However, the role of other drugs could not be ruled out definitely. The patient was managed with antibiotics, corticosteroids, and parenteral fluids and recovered well.
authors.affiliation: Department of Pharmacology, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.
authors.forename: Sujit
authors.initials: S
authors.lastname: Rajagopalan
authors.forename: Sharonjeet
authors.initials: S
authors.lastname: Kaur
authors.forename: Sunil
authors.initials: S
authors.lastname: Dogra
authors.forename: Nusrat
authors.initials: N
authors.lastname: Shafiq
authors.forename: Ashish
authors.initials: A
authors.lastname: Bhalla
authors.forename: Promila
authors.initials: P
authors.lastname: Pandhi
authors.forename: Samir
authors.initials: S
authors.lastname: Malhotra