title: Ginger consumption enhances the thermic effect of food and promotes feelings of satiety without affecting metabolic and hormonal parameters in overweight men: a pilot study.
abstract: Evidence suggests that ginger consumption has anti-inflammatory, anti-hypertensive, glucose-sensitizing, and stimulatory effects on the gastrointestinal tract. This study assessed the effects of a hot ginger beverage on energy expenditure, feelings of appetite and satiety and metabolic risk factors in overweight men. Ten men, age 39.1±3.3 y and body mass index (BMI) 27.2±0.3 kg/m(2), participated in this randomized crossover study. Resting state energy expenditure was measured using indirect calorimetry and for 6h after consumption of a breakfast meal with or without 2 g ginger powder dissolved in a hot water beverage. Subjective feelings of satiety were assessed hourly using visual analog scales (VAS) and blood samples were taken fasted and for 3 h after breakfast consumption. There was no significant effect of ginger on total resting energy expenditure (P=.43) or respiratory quotient (P=.41). There was a significant effect of ginger on thermic effect of food (ginger vs control=42.7±21.4 kcal/d, P=.049) but the area under the curve was not different (P=.43). VAS ratings showed lower hunger (P=.002), lower prospective food intake (P=.004) and greater fullness (P=.064) with ginger consumption versus control. There were no effects of ginger on glucose, insulin, lipids, or inflammatory markers. The results, showing enhanced thermogenesis and reduced feelings of hunger with ginger consumption, suggest a potential role of ginger in weight management. Additional studies are necessary to confirm these findings.
authors.affiliation: Institute of Human Nutrition, Columbia University, New York, NY 10036, USA.
authors.forename: Muhammad S
authors.initials: MS
authors.lastname: Mansour
authors.forename: Yu-Ming
authors.initials: YM
authors.lastname: Ni
authors.forename: Amy L
authors.initials: AL
authors.lastname: Roberts
authors.forename: Michael
authors.initials: M
authors.lastname: Kelleman
authors.forename: Arindam
authors.initials: A
authors.lastname: Roychoudhury
authors.forename: Marie-Pierre
authors.initials: MP
authors.lastname: St-Onge
mesh_terms: D000328:Adult; D019540:Area Under Curve; D002097:C-Reactive Protein / Q000032:analysis; D018592:Cross-Over Studies; D004734:Energy Metabolism / Q000187:drug effects*; D005502:Food; D054439:Ghrelin / Q000097:blood; D020939:Zingiber officinale; D006801:Humans; D008297:Male; D008875:Middle Aged; D050177:Overweight; D010865:Pilot Projects; D012528:Satiety Response / Q000187:drug effects*; D022722:Thermogenesis / Q000187:drug effects*
chemical_list: D054439:Ghrelin; D002097:C-Reactive Protein