title: Sodium methoxide: a simple but highly efficient catalyst for the direct amidation of esters.
abstract: A simple NaOMe catalyst provides superior accessibility to a wide variety of functionalized amides including peptides through direct amination of esters in an atom-economical and environmentally benign way.
authors.affiliation: Graduate School of Pharmaceutical Sciences, Kyushu University and CREST, JST, Fukuoka, Japan. ohshima@phar.kyushu-u.ac.jp
authors.forename: Takashi
authors.initials: T
authors.lastname: Ohshima
authors.forename: Yukiko
authors.initials: Y
authors.lastname: Hayashi
authors.forename: Kazushi
authors.initials: K
authors.lastname: Agura
authors.forename: Yuka
authors.initials: Y
authors.lastname: Fujii
authors.forename: Asako
authors.initials: A
authors.lastname: Yoshiyama
authors.forename: Kazushi
authors.initials: K
authors.lastname: Mashima
mesh_terms: D000577:Amides / Q000737:chemistry*; D000586:Amination; D002384:Catalysis; D004952:Esters / Q000737:chemistry; D055772:Green Chemistry Technology; D000432:Methanol / Q000737:chemistry*; D010455:Peptides / Q000737:chemistry
chemical_list: D000577:Amides; D004952:Esters; D010455:Peptides; D000432:Methanol