title: In vitro activities of antimicrobials against Brucella abortus isolates from cattle in Korea during 1998-2006.
abstract: In vitro activities of 13 antibiotics were assessed against 85 Brucella abortus isolates from naturally infected cattle in the Republic of Korea during 1998-2006, using broth microdilution test. Tetracyclines showed the most excellent activity against B. abortus, displaying MIC values of 0.5 μg/ml or below. In particular, minocycline showed the lowest MIC₅₀/₉₀ values (0.125/0.125 μg/ml) in this study. Among four fluoroquinolones tested, ciprofloxacin (MIC₅₀/₉₀, 0.5/1 μg/ml) and norfloxacin (MIC₅₀/₉₀, 8/8 μg/ml) had the most and the least activities, respectively. Gentamicin (MIC₅₀/₉₀, 1/1 μg/ml) was more effective than streptomycin, erythromycin, rifampin, and chloramphenicol (MIC₅₀/₉₀, 2/2 μg/ml).
authors.affiliation: Animal, Plant and Fisheries Quarantine and Inspection Agency, Anyang 430-824, Korea.
authors.forename: Eun-Jeong
authors.initials: EJ
authors.lastname: Heo
authors.forename: Sung-Il
authors.initials: SI
authors.lastname: Kang
authors.forename: Jong-Wan
authors.initials: JW
authors.lastname: Kim
authors.forename: Moon
authors.initials: M
authors.lastname: Her
authors.forename: Donghee
authors.initials: D
authors.lastname: Cho
authors.forename: Yun-Sang
authors.initials: YS
authors.lastname: Cho
authors.forename: In-Yeong
authors.initials: IY
authors.lastname: Hwang
authors.forename: Jin-San
authors.initials: JS
authors.lastname: Moon
authors.forename: Sung-Hwan
authors.initials: SH
authors.lastname: Wee
authors.forename: Suk-Chan
authors.initials: SC
authors.lastname: Jung
authors.forename: Hyang-Mi
authors.initials: HM
authors.lastname: Nam
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002003:Brucella abortus / Q000187:drug effects* / Q000235:genetics / Q000302:isolation & purification; D002007:Brucellosis, Bovine / Q000382:microbiology*; D002417:Cattle; D008826:Microbial Sensitivity Tests; D056910:Republic of Korea
chemical_list: D000900:Anti-Bacterial Agents