title: Ruthenium-catalyzed intramolecular [2+2+2] cyclization of allene-yne-enes: construction of fused-tricyclic skeletons.
abstract: Three's not a crowd: An intramolecular [2+2+2] cyclization between three different components, allene, alkyne, and alkene, has been realized using a catalytic amount of [Cp*RuCl(cod)] complex (cod = 1,5-cyclooctadiene), and afforded fused-tricyclic compounds in a highly stereoselective manner.
authors.affiliation: Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan. biyo@pharm.hokudai.ac.jp
authors.forename: Nozomi
authors.initials: N
authors.lastname: Saito
authors.forename: Taisuke
authors.initials: T
authors.lastname: Ichimaru
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Sato
mesh_terms: D000466:Alkadienes / Q000737:chemistry*; D000475:Alkenes / Q000737:chemistry*; D000480:Alkynes / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D006575:Heterocyclic Compounds, 3-Ring / Q000138:chemical synthesis* / Q000737:chemistry; D008958:Models, Molecular; D012428:Ruthenium / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000466:Alkadienes; D000475:Alkenes; D000480:Alkynes; D006575:Heterocyclic Compounds, 3-Ring; C439868:1,5-cyclooctadiene; C025947:propadiene; D012428:Ruthenium