title: Formation of CC-type palladacycles with assistance from an apparently innocent NH(CO) functional group.
abstract: A novel cyclometalation pathway to form CC-type palladacycles is reported. Unlike common donor-assisted cyclometalation, the NH(CO) auxiliary group undergoes a deprotonation step to form a palladalactam intermediate. The coordinating nitrogen atom functions as an intramolecular base promoting selective C-H bond cleavage. Without the NH proton, the ortho-N-phenyl C-H is activated instead.
authors.affiliation: Department of Chemistry, National Changhua University of Education, Changhua 50058, Taiwan, ROC.
authors.forename: Jhen-Yi
authors.initials: JY
authors.lastname: Lee
authors.forename: Yao-Huei
authors.initials: YH
authors.lastname: Huang
authors.forename: Shu-Ya
authors.initials: SY
authors.lastname: Liu
authors.forename: Shun-Chu
authors.initials: SC
authors.lastname: Cheng
authors.forename: Yang-Ming
authors.initials: YM
authors.lastname: Jhou
authors.forename: Jenn-Huei
authors.initials: JH
authors.lastname: Lii
authors.forename: Hon Man
authors.initials: HM
authors.lastname: Lee