title: Hepatitis B virus infection in children.
abstract: Hepatitis B can develop in less than 5% of neonates of infected mothers, despite neonatal serovaccination. Most children will develop a chronic hepatitis. Most children are in an immune-tolerant or in an inactive phase. Interferon is the treatment of choice, in the rare cases where it is necessary.
authors.affiliation: Hepato-Metabolic Department, Bambino Gesù Children Hospital, Rome, Italy.
authors.forename: Claudia
authors.initials: C
authors.lastname: Della Corte
authors.forename: Donatella
authors.initials: D
authors.lastname: Comparcola
authors.forename: Valerio
authors.initials: V
authors.lastname: Nobili
mesh_terms: D000998:Antiviral Agents / Q000627:therapeutic use; D002353:Carrier State; D002648:Child; D004279:DNA, Viral / Q000097:blood; D005260:Female; D006509:Hepatitis B / Q000276:immunology / Q000635:transmission; D006514:Hepatitis B Surface Antigens / Q000097:blood; D006513:Hepatitis B e Antigens / Q000097:blood; D019694:Hepatitis B, Chronic / Q000453:epidemiology / Q000628:therapy*; D006801:Humans; D007108:Immune Tolerance; D018445:Infectious Disease Transmission, Vertical; D007372:Interferons / Q000627:therapeutic use; D011247:Pregnancy; D057832:Watchful Waiting
chemical_list: D000998:Antiviral Agents; D004279:DNA, Viral; D006514:Hepatitis B Surface Antigens; D006513:Hepatitis B e Antigens; D007372:Interferons