title: Frequency and trajectory of abnormalities in respiratory rate, temperature and oxygen saturation in severe pneumonia in children.
abstract: The frequency or trajectory of vital sign abnormalities in children with pneumonia has not been described. In a cohort of 2714 patients with severe pneumonia identified and treated as per the World Health Organization definition and recommendations, tachypnea, fever and hypoxia were found in 68.9%, 23.6% and 15.5% of children, respectively. Median oxygen saturation returned to a normal range by 10 hours following initiation of treatment, followed by temperature at 12 hours and respiratory rate at 22 hours for subjects <12 months and at 48 hours for those ≥ 12 months of age.
authors.affiliation: Center for Global Health and Development, Boston University, Boston, MA 02118, USA. rasa@bu.edu
authors.forename: Rasa
authors.initials: R
authors.lastname: Izadnegahdar
authors.forename: Matthew P
authors.initials: MP
authors.lastname: Fox
authors.forename: Donald M
authors.initials: DM
authors.lastname: Thea
authors.forename: Shamim A
authors.initials: SA
authors.lastname: Qazi
mesh_terms: D001831:Body Temperature / Q000502:physiology*; D015331:Cohort Studies; D003105:Colombia / Q000453:epidemiology; D005260:Female; D005869:Ghana / Q000453:epidemiology; D006801:Humans; D007194:India / Q000453:epidemiology; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008800:Mexico / Q000453:epidemiology; D010092:Oximetry; D010100:Oxygen / Q000097:blood*; D010154:Pakistan / Q000453:epidemiology; D011014:Pneumonia / Q000097:blood / Q000453:epidemiology / Q000503:physiopathology*; D016032:Randomized Controlled Trials as Topic; D056152:Respiratory Rate / Q000502:physiology*; D013019:South Africa / Q000453:epidemiology; D014744:Vietnam / Q000453:epidemiology; D055986:Vital Signs; D015024:Zambia / Q000453:epidemiology
chemical_list: D010100:Oxygen