title: Burkitt lymphoma in a child with atopic dermatitis and a 7-year history of regular topical tacrolimus use.
abstract: We describe the case of a boy who presented with abdominal Burkitt lymphoma; he had been regularly using tacrolimus ointment 0.1% for severe recurrent atopic dermatitis for 7 years immediately prior to developing cancer. We present his medical history and review the current knowledge regarding a link between topical tacrolimus and malignancy risk.
authors.affiliation: University of Kentucky College of Medicine, Lexington, KY 40536-0096, USA.
authors.forename: Latawnya
authors.initials: L
authors.lastname: Pleasant
authors.forename: Sean
authors.initials: S
authors.lastname: Skinner
authors.forename: Joseph
authors.initials: J
authors.lastname: Pulliam
authors.forename: Harigovinda
authors.initials: H
authors.lastname: Challa
authors.forename: John
authors.initials: J
authors.lastname: D'Orazio
mesh_terms: D000279:Administration, Cutaneous; D002051:Burkitt Lymphoma / Q000139:chemically induced / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D002648:Child; D003876:Dermatitis, Atopic / Q000150:complications / Q000188:drug therapy*; D003937:Diagnosis, Differential; D006801:Humans; D007077:Ileal Diseases / Q000150:complications / Q000175:diagnosis / Q000601:surgery; D007078:Ileal Neoplasms / Q000139:chemically induced / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D007080:Ileocecal Valve / Q000601:surgery; D007166:Immunosuppressive Agents / Q000008:administration & dosage / Q000009:adverse effects*; D007443:Intussusception / Q000150:complications / Q000175:diagnosis / Q000601:surgery; D008297:Male; D016559:Tacrolimus / Q000008:administration & dosage / Q000009:adverse effects*; D014057:Tomography, X-Ray Computed
chemical_list: D007166:Immunosuppressive Agents; D016559:Tacrolimus