title: Sternal reconstruction for unusual chondrosarcoma: innovative technique.
abstract: The authors report a clinical case of a primary sternal chondrosarcoma, presented as a mass in the anterior mediastinum. The patient was treated with subtotal sternectomy and sternal transplantation followed by radiotherapy. Twelve months after surgery, the patient is in good clinical condition, without any sign of tumor relapse and with normal respiratory mechanics. Primary malignant tumors of the sternum are uncommon and a presentation mimicking thymoma is rare and unreported. The stermal replacement with a cryopreserved allograft sternum is an innovative technique that overcomes the problems related to the prosthetic biocompatibility or to the bone autograft.
authors.affiliation: Thoracic Surgery and Lung Transplantation Unit, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, University of Milan, Via Francesco Sforza, 35, Milan, 20122, Italy.
authors.forename: Mario
authors.initials: M
authors.lastname: Nosotti
authors.forename: Lorenzo
authors.initials: L
authors.lastname: Rosso
authors.forename: Paolo
authors.initials: P
authors.lastname: Mendogni
authors.forename: Davide
authors.initials: D
authors.lastname: Tosi
authors.forename: Alessandro
authors.initials: A
authors.lastname: Palleschi
authors.forename: Antonina
authors.initials: A
authors.lastname: Parafioriti
authors.forename: Luigi
authors.initials: L
authors.lastname: Santambrogio
mesh_terms: D000368:Aged; D001672:Biocompatible Materials; D016025:Bone Transplantation / Q000379:methods*; D002813:Chondrosarcoma / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D013249:Sternum / Q000473:pathology / Q000601:surgery*; D014184:Transplantation, Homologous
chemical_list: D001672:Biocompatible Materials