title: Conformations of individual quadruplex units studied in the context of extended human telomeric DNA.
abstract: G-quadruplex conformations within a sequence of three quadruplex units of human telomeric DNA were studied by two-frequency pulsed electron paramagnetic resonance (EPR) spectroscopy. In contrast to some individual G-quadruplexes, within the higher-order human telomeric sequence a (3+1) hybrid structure is formed.
authors.affiliation: Department of Chemistry and Konstanz Research School Chemical Biology, University of Konstanz, 78457 Konstanz, Germany.
authors.forename: Vijay
authors.initials: V
authors.lastname: Singh
authors.forename: Mykhailo
authors.initials: M
authors.lastname: Azarkh
authors.forename: Malte
authors.initials: M
authors.lastname: Drescher
authors.forename: Jörg S
authors.initials: JS
authors.lastname: Hartig
mesh_terms: D001483:Base Sequence; D004247:DNA / Q000737:chemistry*; D004578:Electron Spin Resonance Spectroscopy; D054856:G-Quadruplexes; D006801:Humans; D008958:Models, Molecular; D008969:Molecular Sequence Data; D016615:Telomere / Q000737:chemistry* / Q000235:genetics
chemical_list: D004247:DNA