title: Leptin and the central control of feeding behavior.
abstract: The discovery of leptin by Friedman and coll. in 1995 was a major step forward in our comprehensive view of energy homeostasis. Since the original paper, a tremendous amount of work has been performed in laboratories all over the world. Many recent reviews have described this work in details. In the present review, we focus on the role of leptin on food intake. It is accepted by most authors working in this field that the control of food intake can be divided in two closely-related system: the homeostatic system and the hedonic system. Leptin has been shown to act on both systems.
authors.affiliation: CNRS, UMR6265 Centre des Sciences du Goût et de l'Alimentation, F-2100 Dijon, France. Luc.Penicaud@u-bourgogne.fr
authors.forename: Luc
authors.initials: L
authors.lastname: Pénicaud
authors.forename: Sophie
authors.initials: S
authors.lastname: Meillon
authors.forename: Laurent
authors.initials: L
authors.lastname: Brondel
mesh_terms: D000818:Animals; D005247:Feeding Behavior / Q000502:physiology*; D006706:Homeostasis; D006801:Humans; D020738:Leptin / Q000172:deficiency / Q000378:metabolism*; D009415:Nerve Net / Q000166:cytology / Q000502:physiology; D009474:Neurons / Q000378:metabolism
chemical_list: D020738:Leptin