title: Cell type-specific eQTLs in the human immune system.
abstract: A new study reports the mapping of gene expression in primary immune cell subsets, showing the presence of cell type-specific cis and trans expression quantitative trait loci (eQTLs). The identification of cell type-specific trans-regulated networks can inform functional studies of susceptibility loci identified from genome-wide association studies for human complex diseases.
authors.affiliation: Robert S. Boas Center for Genomics and Human Genetics, The Feinstein Institute for Medical Research, North Shore-Long Island Jewish Health System, Manhasset, New York, USA. peterg@nshs.edu
authors.forename: Peter K
authors.initials: PK
authors.lastname: Gregersen
mesh_terms: D001402:B-Lymphocytes / Q000378:metabolism*; D005819:Genetic Markers / Q000235:genetics*; D020022:Genetic Predisposition to Disease; D006680:HLA Antigens / Q000235:genetics*; D006801:Humans; D009000:Monocytes / Q000378:metabolism*; D020641:Polymorphism, Single Nucleotide / Q000235:genetics*; D040641:Quantitative Trait Loci / Q000235:genetics*
chemical_list: D005819:Genetic Markers; D006680:HLA Antigens