title: Medication-related problems occurring in people with diabetes during an admission to an adult teaching hospital: a retrospective cohort study.
abstract: OBJECTIVE
  To examine the characteristics of medication-related problems occurring in people with diabetes admitted to hospital and to identify risk factors for medication-related problems.
  
  
  METHODS
  A retrospective cohort study of medication-related problems occurring in patients admitted to an adult, inner-city Australian teaching hospital was conducted over two-years. The risk factors associated with medication-related problems were identified using random effect logistic regression.
  
  
  RESULTS
  There were 9530 admissions of people with diabetes involving 5205 individuals over a two-year period. Medication-related problems were associated with 686 (7.2%) admissions involving 571 individuals (11.0%). The most common medication-related problems were medication errors (64.1%) associated with hypoglycaemia and unintentional overdose. Five factors were significantly associated with medication-related problems: female gender [odds ratio (OR) 1.30, 95% confidence intervals (CI) 1.11-1.52], age of 18-50 years (OR 2.32, CI 1.85-2.91), single marital status (OR 1.46, CI 1.24-1.74), mental and behavioural problems (OR 1.74, 1.43-2.11), and a comorbidity index score of at least one (OR 1.35-1.67).
  
  
  CONCLUSIONS
  Five significant risk factors were associated with medication-related problems in people with diabetes admitted to hospital. These risks need to be considered when developing care plans and interventions to prevent medication-related problems for individuals with diabetes.
authors.affiliation: Melbourne School of Health Science, The University of Melbourne, Level 2, Walter Boas Building, Carlton, Victoria 3053, Australia. krcp@optusnet.com.au
authors.forename: Kate
authors.initials: K
authors.lastname: Claydon-Platt
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Manias
authors.forename: Trisha
authors.initials: T
authors.lastname: Dunning
mesh_terms: D000293:Adolescent; D000328:Adult; D001315:Australia / Q000453:epidemiology; D015331:Cohort Studies; D015897:Comorbidity; D003922:Diabetes Mellitus, Type 1 / Q000188:drug therapy / Q000191:economics / Q000453:epidemiology*; D003924:Diabetes Mellitus, Type 2 / Q000188:drug therapy / Q000191:economics / Q000453:epidemiology*; D005260:Female; D006760:Hospitalization; D006784:Hospitals, Teaching; D006801:Humans; D007003:Hypoglycemia / Q000139:chemically induced / Q000191:economics / Q000453:epidemiology*; D016015:Logistic Models; D008297:Male; D008508:Medication Errors / Q000706:statistics & numerical data*; D008875:Middle Aged; D010349:Patient Compliance; D063487:Prescription Drug Misuse; D012189:Retrospective Studies; D012307:Risk Factors; D055815:Young Adult