title: High-field imaging of neurodegenerative diseases.
abstract: High-field magnetic resonance (MR) imaging is showing potential for imaging of neurodegenerative diseases. 7 T MR imaging is beginning to be used in a clinical research setting and the theoretical benefits of higher signal-to-noise ratio, sensitivity to iron, improved MR angiography, and increased spectral resolution in spectroscopy are being confirmed. Despite the limited number of studies to date, initial results in patients with multiple sclerosis, Alzheimer disease, and Huntington disease show promising additional features in contrast that may help the diagnosis of these disorders.
authors.affiliation: Department of Radiology, C.J. Gorter Center for High Field MR, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, The Netherlands. m.j.versluis@lumc.nl
authors.forename: M J
authors.initials: MJ
authors.lastname: Versluis
authors.forename: J
authors.initials: J
authors.lastname: van der Grond
authors.forename: M A
authors.initials: MA
authors.lastname: van Buchem
authors.forename: P
authors.initials: P
authors.lastname: van Zijl
authors.forename: A G
authors.initials: AG
authors.lastname: Webb
mesh_terms: D001921:Brain / Q000473:pathology*; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D019636:Neurodegenerative Diseases / Q000473:pathology*