title: Bacteruria with group-B streptococcus: is it a risk factor for adverse pregnancy outcomes?
abstract: OBJECTIVE
  To investigate pregnancy outcomes of patients with and without group-B streptococcus (GBS) bacteriuria.
  
  
  METHODS
  A retrospective study comparing pregnancy outcomes of women with GBS bacteriuria during pregnancy, those with positive GBS vaginal cultures and those without GBS colonization during pregnancy was conducted.
  
  
  RESULTS
  A significant linear association was found with regard to intrapartum fever (U-GBS 0.5%, V-GBS 0.3%, no GBS 0.1%, p = 0.001) and chorioamnionitis (U-GBS 3.3%, V-GBS 1%, no GBS 0.7%, p = 0.001). In addition preterm delivery (15.3% vs. 7.9%, p = 0.001) and premature rupture of membranes (10.7% vs. 7.9, p = 0.001) were significantly higher in the U-GBS group compared to no GBS. Woman with U-GBS had higher rates of diabetes mellitus, hypertensive disorders, and habitual abortions as well as a higher risk for intrauterine growth restriction (IUGR). In addition patients with U-GBS underwent induction of labor and cesarean delivery more frequently.
  
  
  CONCLUSIONS
  Our study showed a significant association between U-GBS and adverse obstetrical outcomes. In addition a linear association was found between GBS culture location and obstetric complications. However, GBS was not associated with adverse perinatal outcome in our population.
authors.affiliation: Department of Obstetrics and Gynecology, Soroka University Medical Center, Beer-Sheva, Israel. kessousr@bgu.ac.il
authors.forename: Roy
authors.initials: R
authors.lastname: Kessous
authors.forename: Adi Y
authors.initials: AY
authors.lastname: Weintraub
authors.forename: Ruslan
authors.initials: R
authors.lastname: Sergienko
authors.forename: Tal
authors.initials: T
authors.lastname: Lazer
authors.forename: Fernanda
authors.initials: F
authors.lastname: Press
authors.forename: Arnon
authors.initials: A
authors.lastname: Wiznitzer
authors.forename: Eyal
authors.initials: E
authors.lastname: Sheiner
mesh_terms: D000293:Adolescent; D000328:Adult; D001437:Bacteriuria / Q000175:diagnosis; D016022:Case-Control Studies; D015331:Cohort Studies; D005260:Female; D005322:Premature Rupture of Fetal Membranes / Q000382:microbiology; D006801:Humans; D016014:Linear Models; D016015:Logistic Models; D016017:Odds Ratio; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis; D011256:Pregnancy Outcome; D047928:Premature Birth / Q000382:microbiology; D012189:Retrospective Studies; D012307:Risk Factors; D013290:Streptococcal Infections / Q000175:diagnosis; D013292:Streptococcus agalactiae / Q000302:isolation & purification*; D014621:Vagina / Q000382:microbiology*; D055815:Young Adult