title: Invasive intracranial aspergillosis spread by the pterygopalatine fossa in an immunocompetent patient.
abstract: Aspergillosis of the central nervous system (CNS) is an uncommon infection, mainly found in immunocompromised patients but rarely seen among immunocompetent patients. Herein we describe a 57 year-old immunocompetent man who suffered intracranial aspergillosis spread by the pterygopalatine fossa (PPF) following a tooth extraction. Based on magnetic resonance imaging (MRI) characteristics, in this report we focus on the spreading routes of CNS aspergillosis via communicative structures of the PPF, the relationship between clinical manifestations and the locations of the lesion, and propose a therapeutic strategy to improve the prognosis.
authors.affiliation: Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
authors.forename: Anqi
authors.initials: A
authors.lastname: Xiao
authors.forename: Shu
authors.initials: S
authors.lastname: Jiang
authors.forename: Yi
authors.initials: Y
authors.lastname: Liu
authors.forename: Kaihong
authors.initials: K
authors.lastname: Deng
authors.forename: Chao
authors.initials: C
authors.lastname: You
mesh_terms: D001927:Brain Diseases / Q000175:diagnosis / Q000382:microbiology*; D006801:Humans; D007121:Immunocompetence; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D020953:Neuroaspergillosis / Q000175:diagnosis / Q000382:microbiology*; D056739:Pterygopalatine Fossa / Q000382:microbiology*; D014081:Tooth Extraction / Q000009:adverse effects