title: Local resection for rectal tumors: comparative study of transanal endoscopic microsurgery vs. conventional transanal excision - the experience in China.
abstract: OBJECTIVE
  To compare the operative range,safety and therapeutic effect of local resection of rectal tumors by using transanal endoscopic microsurgery and conventional transanal excision.
  
  
  METHODS
  We reviewed data from 76 patients treated using conventional TAE during the period from January 2003 to July 2006 and 53 patients treated using TEM during the period from September 2006 to February 2010 in the Ruijin Hospital affiliated with the Shanghai Jiaotong University School of Medicine.
  
  
  RESULTS
  Age, gender, tumor size, blood loss and postoperative hospital stay were similar in the 2 groups. The median distance from the anal verge was significantly higher in the TEM group than in the TAE group. Operation time was significantly longer in the TEM group than in the TAE group.During the median follow-up of 40 months, the LRR in the TEM group was lower than that in the TAE group,especially for tumors that are larger (>3cm) and located higher (>8cm from the anal verge) and pT1 carcinomas.
  
  
  CONCLUSIONS
  TEM is a safe, effective and minimally invasive surgical technique for the treatment of early rectal neoplasms. Compared to conventional TAE,TEM has a broader operative range and a better therapeutic effect.
authors.affiliation: Department of General Surgery, RuiJin Hospital affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China.
authors.forename: Yi
authors.initials: Y
authors.lastname: Han
authors.forename: Yong-gang
authors.initials: YG
authors.lastname: He
authors.forename: Mou-Bin
authors.initials: MB
authors.lastname: Lin
authors.forename: Ya-jie
authors.initials: YJ
authors.lastname: Zhang
authors.forename: Yin
authors.initials: Y
authors.lastname: Lu
authors.forename: Xiaoshun
authors.initials: X
authors.lastname: Jin
authors.forename: Jian-Wen
authors.initials: JW
authors.lastname: Li
mesh_terms: D000236:Adenoma / Q000473:pathology / Q000601:surgery*; D002276:Carcinoid Tumor / Q000473:pathology / Q000601:surgery*; D002277:Carcinoma / Q000473:pathology / Q000601:surgery*; D002681:China; D013505:Digestive System Surgical Procedures / Q000009:adverse effects; D004724:Endoscopy / Q000009:adverse effects; D005260:Female; D006801:Humans; D053208:Kaplan-Meier Estimate; D007902:Length of Stay; D008297:Male; D008866:Microsurgery / Q000009:adverse effects; D008875:Middle Aged; D015999:Multivariate Analysis; D019106:Postoperative Hemorrhage / Q000209:etiology; D016016:Proportional Hazards Models; D012004:Rectal Neoplasms / Q000473:pathology / Q000601:surgery*; D012189:Retrospective Studies; D013997:Time Factors; D016896:Treatment Outcome; D047368:Tumor Burden