title: [Fatal Clostridium sordellii infection originated in an ovarian cyst].
abstract: Clostridium sordellii is a Gram-positive bacterium which can cause a serious toxic shock syndrome with a mortality of up to 69%. C. sordellii is a part of the normal vaginal flora in up to 10% of all women. This case describes a fatal case of a healthy 49 year-old woman with a C. sordellii-infection originating from an ovarian cyst. Quick diagnosis is difficult because of the non-specific flu-like symptoms. Survival requires immediate source control and specific antibiotic therapy capable of suppressing toxin production. In rodents superantigen antibodies have shown neutralizing effects.
authors.affiliation: Anæstesiologisk Afdeling Z, Bispebjerg Hospital, Denmark. jensbjerregaard@hotmail.com
authors.forename: Jens Holst
authors.initials: JH
authors.lastname: Bjerregaard
authors.forename: Charlotte
authors.initials: C
authors.lastname: Bülow
authors.forename: Laura Katrine
authors.initials: LK
authors.lastname: Buskov
authors.forename: Jon Gitz
authors.initials: JG
authors.lastname: Holler
mesh_terms: D000230:Adenocarcinoma / Q000000981:diagnostic imaging / Q000382:microbiology; D003015:Clostridium Infections / Q000382:microbiology*; D047989:Paraclostridium sordellii / Q000302:isolation & purification; D015179:Colorectal Neoplasms / Q000000981:diagnostic imaging / Q000382:microbiology; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008875:Middle Aged; D010048:Ovarian Cysts / Q000382:microbiology*; D012772:Shock, Septic / Q000382:microbiology*; D014057:Tomography, X-Ray Computed