title: Malignant perivascular epithelioid cell tumor of the uterus.
abstract: Perivascular epithelioid cell tumors (PEComas) are a rare collection of tumors arising in a wide array of anatomic locations and characterized by a myomelanocytic phenotype. PEComas which occur in non-classic anatomic distributions are known as perivascular epithelioid cell tumor-not otherwise specified (PEComa-NOS), and one of the most common primary sites for PEComa-NOS is the uterus. The risk of aggressive behavior of these tumors has been linked to a number of factors evaluable on pathologic review following initial surgical resection. We report a case of PEComa-NOS of the uterus with multiple high-risk features, including frank vascular invasion, with no evidence of recurrent disease 18 months following initial surgical resection.
authors.affiliation: Department of Medical Oncology and.
authors.forename: Jonathan S
authors.initials: JS
authors.lastname: Bleeker
authors.forename: J Fernando
authors.initials: JF
authors.lastname: Quevedo
authors.forename: Andrew L
authors.initials: AL
authors.lastname: Folpe