title: Long-term retention of injected aluminium-26.
abstract: Data previously reported on the whole-body retention of aluminium-26 ((26)Al) in a male volunteer are extended to 8 years after intravenous administration as citrate, when only ~2% of the injected tracer remained. The extended data, combined with a report elsewhere of the late urinary and faecal excretion of (26)Al by this subject, reinforce indications that transdermal losses contribute to the clearance of systemic aluminium and mitigate its long-term accumulation from chronic exposure.
authors.affiliation: AEA Technology, Harwell, Didcot, Oxon, UK. drd.newton@hotmail.co.uk
authors.forename: D
authors.initials: D
authors.lastname: Newton
authors.forename: R J
authors.initials: RJ
authors.lastname: Talbot
mesh_terms: D000328:Adult; D001822:Body Burden; D019343:Citric Acid / Q000378:metabolism / Q000493:pharmacokinetics*; D005243:Feces; D006207:Half-Life; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D011829:Radiation Dosage; D011868:Radioisotopes / Q000378:metabolism / Q000493:pharmacokinetics*; D013997:Time Factors
chemical_list: D011868:Radioisotopes; D019343:Citric Acid; C455846:aluminum citrate