title: Logic gates for multiplexed analysis of Hg2+ and Ag+.
abstract: The design of devices with multiple functions, simple handling procedures and sufficient sensitivity has drawn great interests in the field of analysis. Metal-nucleotide based pairs, such as T-Hg(2+)-T and C-Ag(+)-C complexes accompanied by SYBR Green I (SG), are used to selectively bind duplex-strand DNA by observing a bright fluorescence signal in this work, thus yielding a simple method for the rapid detection of Hg(2+) and Ag(+) without a complex labeling process. Based on this principle, 'OR' and 'AND' logic gates for the multiplexed analysis of Hg(2+) and Ag(+) were developed, and their practical application for the detection of Hg(2+) and Ag(+) in drinking water was reported.
authors.affiliation: MOE Key Laboratory of Analysis and Detection for Food Safety, Department of Chemistry, Fuzhou University, Fujian, China.
authors.forename: Guiyun
authors.initials: G
authors.lastname: Zhang
authors.forename: Wenlie
authors.initials: W
authors.lastname: Lin
authors.forename: Weiqiang
authors.initials: W
authors.lastname: Yang
authors.forename: Zhenyu
authors.initials: Z
authors.lastname: Lin
authors.forename: Longhua
authors.initials: L
authors.lastname: Guo
authors.forename: Bin
authors.initials: B
authors.lastname: Qiu
authors.forename: Guonan
authors.initials: G
authors.lastname: Chen
mesh_terms: D052160:Benzothiazoles; D004247:DNA / Q000032:analysis; D003959:Diamines; D060766:Drinking Water / Q000032:analysis; D007477:Ions / Q000737:chemistry; D008628:Mercury / Q000032:analysis*; D009930:Organic Chemicals / Q000737:chemistry; D011804:Quinolines; D012834:Silver / Q000032:analysis*; D013050:Spectrometry, Fluorescence
chemical_list: D052160:Benzothiazoles; D003959:Diamines; D060766:Drinking Water; D007477:Ions; D009930:Organic Chemicals; D011804:Quinolines; C098022:SYBR Green I; D012834:Silver; D004247:DNA; D008628:Mercury