title: Modulating the precision of recurrent bursts in cultured neural networks.
abstract: Synchronized bursts are a very common feature in biological neural networks, and they play an important role in various brain functions and neurological diseases. This Letter investigates "recurrent synchronized bursts" induced by a single pulse stimulation in cultured networks of rat cortical neurons. We look at how the precision in their arrival times can be modified by a noble time-delayed stimulation protocol, which we term as "Δt training." The emergence of recurrent bursts and the change of the precision in their arrival times can be explained by the stochastic resonance of a damped, subthreshold, neural oscillation.
authors.affiliation: Center for Cell Dynamics and Department of Physics, Korea University, Seoul 136-701, Korea.
authors.forename: Joon Ho
authors.initials: JH
authors.lastname: Choi
authors.forename: June Hoan
authors.initials: JH
authors.lastname: Kim
authors.forename: Ryoun
authors.initials: R
authors.lastname: Heo
authors.forename: Kyoung J
authors.initials: KJ
authors.lastname: Lee
mesh_terms: D000818:Animals; D001683:Biological Clocks; D002478:Cells, Cultured; D002540:Cerebral Cortex / Q000166:cytology; D008959:Models, Neurological; D009415:Nerve Net / Q000166:cytology / Q000502:physiology*; D009474:Neurons / Q000166:cytology / Q000502:physiology*; D051381:Rats; D013269:Stochastic Processes