title: The prevalence of detrusor overactivity amongst patients with symptoms of overactive bladder: a retrospective cohort study.
abstract: OBJECTIVE
  Overactive bladder (OAB) is a symptom-based condition consisting of urgency, with or without incontinence, usually with frequency and nocturia. There are many potential causes of OAB, yet many patients are prescribed anticholinergic medications empirically. This study aimed to determine what proportion of patients presenting for urogynecologic assessment with symptoms of OAB had urodynamic detrusor overactivity (DO).
  
  
  METHODS
  Retrospective chart review was performed for 220 consecutive patient referrals. Demographic data, physical exam information, and urodynamic results were collected. The t test and Fisher's exact test were used for statistical analyses.
  
  
  RESULTS
  The prevalence of DO was 11.8 % in this population. Urogenital atrophy and incomplete emptying were more common. Patients with DO were older and more often menopausal than those without DO. Significant prolapse was a common finding amongst patients with OAB symptoms.
  
  
  CONCLUSIONS
  Patients with symptoms of OAB should undergo pelvic examination and assessment of post-void residuals before being initiated on anticholinergic medication.
authors.affiliation: Division of Urogynecology and Reconstructive Pelvic Surgery, Mount Sinai Hospital, 700 University Avenue, Rm 801, Toronto, ON, Canada M5G 1Z5. diamond.phaedra@gmail.com
authors.forename: P
authors.initials: P
authors.lastname: Diamond
authors.forename: S
authors.initials: S
authors.lastname: Hassonah
authors.forename: M
authors.initials: M
authors.lastname: Alarab
authors.forename: D
authors.initials: D
authors.lastname: Lovatsis
authors.forename: H P
authors.initials: HP
authors.lastname: Drutz
mesh_terms: D000368:Aged; D018680:Cholinergic Antagonists / Q000627:therapeutic use; D015331:Cohort Studies; D005260:Female; D058869:Gynecological Examination; D006801:Humans; D008875:Middle Aged; D009130:Muscle, Smooth / Q000503:physiopathology*; D015995:Prevalence; D012189:Retrospective Studies; D053201:Urinary Bladder, Overactive / Q000188:drug therapy / Q000453:epidemiology* / Q000503:physiopathology*; D014563:Urodynamics / Q000502:physiology
chemical_list: D018680:Cholinergic Antagonists