title: Fabrication of Langmuir-Blodgett films using amphiphilic peptides.
abstract: To introduce self-organization ability of transmembrane proteins into Langmuir (L) and Langmuir-Blodgett (LB) techniques, we focused on "amphiphilic peptide" (AP) which is composed of two distinct hydrophilic and hydrophobic domains. Three types of APs of different average hydropathies were used to prepare the AP/lipid mixed L and LB films. According to the circular dichroism spectra, the secondary structures of APs were not uniform but were a mixture of alpha-helix, beta-strand and random coil. The fraction of alpha-helix was higher for lower hydropathy AP. The interaction between AP and lipid in the L film and the structure of the LB film were also depended on the APs used.
authors.affiliation: Faculty of Electrical Engineering, Graduate School of Science and Technology, Meiji University, Kawasaki 214-8571, Japan.
authors.forename: Ken
authors.initials: K
authors.lastname: Togashi
authors.forename: Takumi
authors.initials: T
authors.lastname: Iizuka
authors.forename: Noritaka
authors.initials: N
authors.lastname: Kato
authors.forename: Takanori
authors.initials: T
authors.lastname: Sasaki
authors.forename: Yuri
authors.initials: Y
authors.lastname: Mukai
mesh_terms: D003460:Crystallization / Q000379:methods*; D008051:Lipid Bilayers / Q000737:chemistry*; D008422:Materials Testing; D008567:Membranes, Artificial; D049329:Nanostructures / Q000737:chemistry* / Q000648:ultrastructure*; D010316:Particle Size; D010455:Peptides / Q000737:chemistry*; D013499:Surface Properties; D013501:Surface-Active Agents / Q000737:chemistry*
chemical_list: D008051:Lipid Bilayers; D008567:Membranes, Artificial; D010455:Peptides; D013501:Surface-Active Agents