title: Cutaneous anaplastic large cell lymphomas: a report of 9 cases from Thailand.
abstract: BACKGROUND
  Anaplastic large cell lymphoma (ALCL) is one type of lymphoma, which is characterized by the proliferation of pleomorphic large atypical lymphoid cells expressing CD30 antigen. ALCL involving skin can be either primary cutaneous disease or cutaneous involvement secondary from systemic disease. Data of clinical manifestation of cutaneous ALCL in Thai patients is limited. ALCL in Thai patients may differ from other groups of patients.
  
  
  OBJECTIVE
  To study the clinical manifestation of cutaneous ALCL in patients of Faculty of Medicine Siriraj Hospital, Thailand.
  
  
  METHODS
  Medical records of nine patients with histopathologic diagnosis of ALCL from skin biopsy at Faculty of Medicine Siriraj Hospital were reviewed.
  
  
  RESULTS
  Of nine patients, four patients were diagnosed as primary cutaneous ALCL, four patients as systemic ALCL with secondary skin involvement, and one patient as combined primary cutaneous ALCL and lymphomatoid papulosis. Three primary cutaneous ALCL patients had no recurrence of disease during 6-year follow-up. However all systemic ALCL patients died at one day to 1.5 years after diagnosis.
  
  
  CONCLUSIONS
  Clinical manifestation and clinical course of Thai patients with anaplastic large cell lymphoma corresponded with the data from other patient population.
authors.affiliation: Department of Dermatology, Faculty of Medicine Siriraj Hospital, Bangkok, Thailand. doctorsasima@gmail.com
authors.forename: Sasima
authors.initials: S
authors.lastname: Eimpunth
authors.forename: Panitta
authors.initials: P
authors.lastname: Sittinamsuwan
authors.forename: Penvadee
authors.initials: P
authors.lastname: Pattanaprichakul
authors.forename: Narumol
authors.initials: N
authors.lastname: Silpa-archa
authors.forename: Piyaroj
authors.initials: P
authors.lastname: Sethabutra
authors.forename: Leena
authors.initials: L
authors.lastname: Chularojanamontri
authors.forename: Suchanan
authors.initials: S
authors.lastname: Hanamornroongruang
authors.forename: Punkae
authors.initials: P
authors.lastname: Mahaisavariya
mesh_terms: D000293:Adolescent; D000328:Adult; D006801:Humans; D007150:Immunohistochemistry; D017728:Lymphoma, Large-Cell, Anaplastic / Q000175:diagnosis* / Q000378:metabolism / Q000473:pathology; D008875:Middle Aged; D012189:Retrospective Studies; D012878:Skin Neoplasms / Q000175:diagnosis* / Q000378:metabolism / Q000473:pathology; D013785:Thailand; D055815:Young Adult