title: Lewis base promoted intramolecular acylcyanation of α-substituted activated alkenes: construction of ketones bearing β-quaternary carbon centers.
abstract: A novel phosphine-promoted intramolecular acylcyanation of α-substituted activated alkenes has been developed, which provides a unique access to densely functionalized acyclic ketones bearing β-quaternary carbon centers with a remarkable feature that both α- and β-positions of activated alkene are functionalized.
authors.affiliation: Department of Organic Chemistry, College of Chemistry, Jilin University, 2699 Qianjin Street, Changchun 130012, China.
authors.forename: Zhe
authors.initials: Z
authors.lastname: Zhuang
authors.forename: Jian-Ming
authors.initials: JM
authors.lastname: Chen
authors.forename: Feng
authors.initials: F
authors.lastname: Pan
authors.forename: Wei-Wei
authors.initials: WW
authors.lastname: Liao