title: Offline fusion of co-registered intravascular ultrasound and frequency domain optical coherence tomography images for the analysis of human atherosclerotic plaques.
abstract: OBJECTIVE
  To demonstrate the feasibility and potential usefulness of an offline fusion of matched optical coherence tomography (OCT) and intravascular ultrasound (IVUS)/virtual histology (IVUS-VH) images.
  
  
  RESULTS
  A total of nine matched OCT, IVUS, and IVUS-VH cross-sections were fused according to a methodology described in this report. On the basis of the fused images, an OCT-IVUS-VH tissue classification algorithm is proposed taking into account the individual strength of both techniques.
  
  
  CONCLUSIONS
  Offline fusion of co-registered IVUS and OCT is feasible and combines the strengths of both imaging modalities, potentially improving the diagnostic accuracy of plaque characterisation.
authors.affiliation: Department of Cardiology, Thoraxcenter, Erasmus Medical Center, Rotterdam, The Netherlands.
authors.forename: Lorenz
authors.initials: L
authors.lastname: Räber
authors.forename: Jung Ho
authors.initials: JH
authors.lastname: Heo
authors.forename: Maria D
authors.initials: MD
authors.lastname: Radu
authors.forename: Hector M
authors.initials: HM
authors.lastname: Garcia-Garcia
authors.forename: Giulio G
authors.initials: GG
authors.lastname: Stefanini
authors.forename: Aris
authors.initials: A
authors.lastname: Moschovitis
authors.forename: Jouke
authors.initials: J
authors.lastname: Dijkstra
authors.forename: Henning
authors.initials: H
authors.lastname: Kelbaek
authors.forename: Stephan
authors.initials: S
authors.lastname: Windecker
authors.forename: Patrick W
authors.initials: PW
authors.lastname: Serruys
mesh_terms: D000465:Algorithms; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging* / Q000473:pathology*; D003331:Coronary Vessels / Q000000981:diagnostic imaging* / Q000473:pathology*; D005240:Feasibility Studies; D005355:Fibrosis; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D009336:Necrosis; D058226:Plaque, Atherosclerotic; D011237:Predictive Value of Tests; D041623:Tomography, Optical Coherence; D018084:Ultrasonography, Interventional; D061205:Vascular Calcification / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000473:pathology