title: Synthesis and pharmacological evaluation of new 4,4-diphenylbut-3-enyl derivatives of 4-hydroxybutanamides as GABA uptake inhibitors.
authors.affiliation: Department of Physicochemical Drug Analysis Jagiellonian University Medical College, 9 Medyczna St., 30-688 Kraków, Poland.
authors.forename: Paula
authors.initials: P
authors.lastname: Kowalczyk
authors.forename: Georg
authors.initials: G
authors.lastname: Höfner
authors.forename: Klaus T
authors.initials: KT
authors.lastname: Wanner
authors.forename: Katarzyna
authors.initials: K
authors.lastname: Kulig
mesh_terms: D000818:Animals; D000927:Anticonvulsants / Q000138:chemical synthesis* / Q000494:pharmacology*; D050485:GABA Plasma Membrane Transport Proteins / Q000187:drug effects* / Q000378:metabolism; D058805:GABA Uptake Inhibitors / Q000138:chemical synthesis* / Q000494:pharmacology*; D006877:Hydroxamic Acids / Q000138:chemical synthesis* / Q000494:pharmacology*; D051379:Mice; D015394:Molecular Structure; D013329:Structure-Activity Relationship; D005680:gamma-Aminobutyric Acid / Q000378:metabolism*
chemical_list: D000927:Anticonvulsants; D050485:GABA Plasma Membrane Transport Proteins; D058805:GABA Uptake Inhibitors; D006877:Hydroxamic Acids; D005680:gamma-Aminobutyric Acid; C079264:Slc6a11 protein, mouse; C493414:Slc6a1 protein, mouse; C490439:Slc6a12 protein, mouse; C493419:Slc6a13 protein, mouse