title: Clinical utility of mental state screening as a predictor of intellectual outcomes 6 months after diagnosis of type 1 diabetes.
abstract: BACKGROUND
  Screening tests of basic cognitive status or 'mental state' have been shown to predict mortality and functional outcomes in adults. This study examined the relationship between mental state and outcomes in children with type 1 diabetes.
  
  
  OBJECTIVE
  We aimed to determine whether mental state at diagnosis predicts longer term cognitive function of children with a new diagnosis of type 1 diabetes.
  
  
  METHODS
  Mental state of 87 patients presenting with newly diagnosed type 1 diabetes was assessed using the School-Years Screening Test for the Evaluation of Mental Status. Cognitive abilities were assessed 1 wk and 6 months postdiagnosis using standardized tests of attention, memory, and intelligence.
  
  
  RESULTS
  Thirty-seven children (42.5%) had reduced mental state at diagnosis. Children with impaired mental state had poorer attention and memory in the week following diagnosis, and, after controlling for possible confounding factors, significantly lower IQ at 6 months compared to those with unimpaired mental state (p < 0.05).
  
  
  CONCLUSIONS
  Cognition is impaired acutely in a significant number of children presenting with newly diagnosed type 1 diabetes. Mental state screening is an effective method of identifying children at risk of ongoing cognitive difficulties in the days and months following diagnosis. Clinicians may consider mental state screening for all newly diagnosed diabetic children to identify those at risk of cognitive sequelae.
authors.affiliation: Diabetes and Child Neuropsychology Research Groups, Murdoch Childrens Research Institute, Melbourne, Victoria, Australia. caroline.nadebaum@mcri.edu.au
authors.forename: Caroline
authors.initials: C
authors.lastname: Nadebaum
authors.forename: Shannon E
authors.initials: SE
authors.lastname: Scratch
authors.forename: Elisabeth A
authors.initials: EA
authors.lastname: Northam
authors.forename: Fergus J
authors.initials: FJ
authors.lastname: Cameron
mesh_terms: D000293:Adolescent; D001288:Attention; D002648:Child; D003072:Cognition Disorders / Q000175:diagnosis* / Q000209:etiology; D003922:Diabetes Mellitus, Type 1 / Q000150:complications* / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008297:Male; D008568:Memory; D014888:Wechsler Scales