title: [Efficacy of levofloxacin 500 mg for middle ear diseases].
abstract: We examined the cases that prescribed levofloxacin (LVFX) 500mg for middle ear diseases in our hospital. LVFX 500mg was prescribed in 18 cases (7 male, 11 female, 24-81 years old). LVFX was mainly used for the following clinical conditions, 1) otitis media with granulation proliferation: 3 cases, 2) infection to an artificial materials : 5 cases, 3) treatment for or prevention against the inflammation of the inner ear: 4 cases. Three of eighteen cases were ineffective by LVFX treatment. Bacteriological examination indicated LVFX-resistant MRSA or Pseudomonas aeruginosa were isolated in these three cases.
authors.affiliation: Department of Otorhinolaryngology, Graduate School of Medical Sciences, Kyushu University 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.
authors.forename: Takashi
authors.initials: T
authors.lastname: Kimitsuki
authors.forename: Takamasa
authors.initials: T
authors.lastname: Yoshida
authors.forename: Shizuo
authors.initials: S
authors.lastname: Komune
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D004427:Ear Diseases / Q000188:drug therapy*; D004432:Ear, Middle; D005260:Female; D006801:Humans; D064704:Levofloxacin; D008297:Male; D008875:Middle Aged; D015242:Ofloxacin / Q000008:administration & dosage*; D010033:Otitis Media / Q000188:drug therapy
chemical_list: D000900:Anti-Bacterial Agents; D064704:Levofloxacin; D015242:Ofloxacin