title: Efficacy of a modified pharmacomechanical thrombolysis technique for endovascular treatment of thrombosed prosthetic arteriovenous grafts.
abstract: OBJECTIVE
  We applied a modified pharmacomechanical thrombolysis (PMT) technique to endovascular treatment of thrombosed arteriovenous (AV) grafts without the use of any mechanical thrombectomy devices. The aim of this study was to evaluate the efficacy of the PMT technique in the treatment of thrombosed AV grafts by analyzing the long-term patency.
  
  
  METHODS
  Eighty-two patients with thrombosed AV grafts were treated with the PMT technique. AV graft surveillance to detect failing/failed access was followed by endovascular treatment.
  
  
  RESULTS
  The technical and clinical success rates were 95% and 95%, respectively. The total number of thrombolysis sessions was 279. A post-intervention primary patency rate was 45% and 22% at 12 and 24 months, respectively. The secondary patency rate was 96% and 91% at 12 and 24 months, respectively. No major complications were noticed.
  
  
  CONCLUSIONS
  The modified PMT technique is effective in endovascular treatment of thrombosed AV grafts.
authors.affiliation: Department of Radiology and Medical Research Institute, School of Medicine, Ewha Womans University, Seoul 158-710, Korea.
authors.forename: Sun Young
authors.initials: SY
authors.lastname: Choi
authors.forename: Byung Gil
authors.initials: BG
authors.lastname: Choi
authors.forename: Kum Hyun
authors.initials: KH
authors.lastname: Han
authors.forename: Ho Jong
authors.initials: HJ
authors.lastname: Chun
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000792:Angiography; D000800:Angioplasty, Balloon; D001166:Arteriovenous Shunt, Surgical; D005260:Female; D006083:Graft Occlusion, Vascular / Q000628:therapy*; D006489:Hemostatic Techniques; D006801:Humans; D008297:Male; D008875:Middle Aged; D011138:Polytetrafluoroethylene; D016016:Proportional Hazards Models; D015641:Radiography, Interventional; D006435:Renal Dialysis; D012189:Retrospective Studies; D015607:Stents; D015912:Thrombolytic Therapy / Q000379:methods*; D016896:Treatment Outcome; D014654:Vascular Patency
chemical_list: D011138:Polytetrafluoroethylene