title: Stereoselective total synthesis of nemorosone.
abstract: The highly stereoselective total synthesis of nemorosone via a new approach to the bicyclo[3.3.1]nonane-2,4,9-trione core which features intramolecular cyclopropanation of an α-diazo ketone, stereoselective alkylation at the C8 position, and regioselective ring-opening of cyclopropane is described. The total synthesis of nemorosone includes chemo- and stereoselective hydrogenation directed by the internal alkene.
authors.affiliation: Department of Chemistry and Biochemistry, Faculty of Science and Engineering, Waseda University, 3-4-1 Ohkubo, Shinjuku-ku, Tokyo 169-8555, Japan.
authors.forename: Masahiro
authors.initials: M
authors.lastname: Uwamori
authors.forename: Aya
authors.initials: A
authors.lastname: Saito
authors.forename: Masahisa
authors.initials: M
authors.lastname: Nakada