title: Optical coherence tomography for guidance of distal cell recrossing in bifurcation stenting: choosing the right cell matters.
abstract: OBJECTIVE
  The aim of this study was to assess the ability of optical coherence tomography (OCT) to guide recrossing during percutaneous coronary interventions in bifurcations and to reduce strut malapposition.
  
  
  RESULTS
  Fifty-two patients undergoing elective treatment of bifurcation lesions using provisional stenting as default strategy were included in the study. Patients were divided into two groups: OCT-guided stent recrossing (group 1, n=12), and angiography-guided recrossing (group 2, n=40). Malapposition in the various bifurcation segments was compared in the two groups, using propensity score analysis to correct for confounders. In 4/12 patients (33%) of the OCT-guided group after the first attempt to recross the stent towards the SB the wire was found to have crossed in a proximal cell, requiring a second and in one case a third attempt to successfully cross through a distal cell. Patients who were treated using OCT-guided recrossing had a significantly lower number of malapposed stent struts, especially in the quadrants towards the SB ostium (9.5%[7.5-17.4%] vs 42.3%[31.2-54.7%] in the angiography-guided group, p<0.0001).
  
  
  CONCLUSIONS
  The rate of strut malapposition was significantly reduced when OCT was used to confirm that wire recrossing was performed in a distal cell of the SB ostium.
authors.affiliation: Cardiovascular Biomedical Research Unit, Royal Brompton Hospital, London, United Kingdom.
authors.forename: Eduardo
authors.initials: E
authors.lastname: Alegría-Barrero
authors.forename: Nicolas
authors.initials: N
authors.lastname: Foin
authors.forename: Pak Hei
authors.initials: PH
authors.lastname: Chan
authors.forename: Dimitrios
authors.initials: D
authors.lastname: Syrseloudis
authors.forename: Alistair C
authors.initials: AC
authors.lastname: Lindsay
authors.forename: Konstantinos
authors.initials: K
authors.lastname: Dimopolous
authors.forename: Rafael
authors.initials: R
authors.lastname: Alonso-González
authors.forename: Nicola
authors.initials: N
authors.lastname: Viceconte
authors.forename: Ranil
authors.initials: R
authors.lastname: De Silva
authors.forename: Carlo
authors.initials: C
authors.lastname: Di Mario
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D015906:Angioplasty, Balloon, Coronary / Q000009:adverse effects; D017023:Coronary Angiography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015607:Stents / Q000009:adverse effects; D041623:Tomography, Optical Coherence / Q000379:methods*