title: Response of commiphora mukul (guggulu) on melatonin induced hypothyroidism.
abstract: The results of this study indicate that melatonin induces hypothyroidism in mice within eight days. Simultaneous administration of melatonin and petroleum ether extract of Commiphora mukul brings about a significant improvement in thyroid structure and function. Further, melatonin induced hypothyroidism is although a little reversible yet it is normalized quickly after C. mukul treatment. These data suggest that C. mukul directly stimulates thyroid function probably through some enzymatic mechanisms.
authors.affiliation: Department of Kayachikitsa and Shatya Shatyakya, Institute of Medical Sciences, Banaras Hindu University, Varanasi, 221 005, India.
authors.forename: A K
authors.initials: AK
authors.lastname: Singh
authors.forename: S N
authors.initials: SN
authors.lastname: Tripathi
authors.forename: G C
authors.initials: GC
authors.lastname: Prasad