title: A sensitive fluorescence strategy for telomerase detection in cancer cells based on T7 exonuclease-assisted target recycling amplification.
abstract: A sensitive fluorescence strategy based on T7 exonuclease-assisted target recycling amplification was developed for telomerase detection in cancer cells. The novel strategy improved the fluorescence signal and sensitivity compared with the previously reported methods.
authors.affiliation: State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, 410082, P. R. China.
authors.forename: Hai-bo
authors.initials: HB
authors.lastname: Wang
authors.forename: Shuang
authors.initials: S
authors.lastname: Wu
authors.forename: Xia
authors.initials: X
authors.lastname: Chu
authors.forename: Ru-Qin
authors.initials: RQ
authors.lastname: Yu
mesh_terms: D015374:Biosensing Techniques; D045744:Cell Line, Tumor; D005090:Exodeoxyribonucleases / Q000378:metabolism*; D006801:Humans; D009369:Neoplasms / Q000201:enzymology*; D013050:Spectrometry, Fluorescence; D019098:Telomerase / Q000378:metabolism*
chemical_list: D019098:Telomerase; D005090:Exodeoxyribonucleases; C046264:gene b exonuclease