title: Magnetic control system targeted for capsule endoscopic operations in the stomach--design, fabrication, and in vitro and ex vivo evaluations.
abstract: This paper presents a novel solution of a hand-held external controller to a miniaturized capsule endoscope in the gastrointestinal (GI) tract. Traditional capsule endoscopes move passively by peristaltic wave generated in the GI tract and the gravity, which makes it impossible for endoscopists to manipulate the capsule endoscope to the diagnostic disease areas. In this study, the main objective is to present an endoscopic capsule and a magnetic field navigator (MFN) that allows endoscopists to remotely control the locomotion and viewing angle of an endoscopic capsule. The attractive merits of this study are that the maneuvering of the endoscopic capsule can be achieved by the external MFN with effectiveness, low cost, and operation safety, both from a theoretical and an experimental point of view. In order to study the magnetic interactions between the endoscopic capsule and the external MFN, a magnetic-analysis model is established for computer-based finite-element simulations. In addition, experiments are conducted to show the control effectiveness of the MFN to the endoscopic capsule. Finally, several prototype endoscopic capsules and a prototype MFN are fabricated, and their actual capabilities are experimentally assessed via in vitro and ex vivo tests using a stomach model and a resected porcine stomach, respectively. Both in vitro and ex vivo test results demonstrate great potential and practicability of achieving high-precision rotation and controllable movement of the capsule using the developed MFN.
authors.affiliation: Department of Internal Medicine, Wan Fang Hospital, Taipei Medical University, Taipei 116, Taiwan. gslien@tmu.edu.tw
authors.forename: Gi-Shih
authors.initials: GS
authors.lastname: Lien
authors.forename: Chih-Wen
authors.initials: CW
authors.lastname: Liu
authors.forename: Joe-Air
authors.initials: JA
authors.lastname: Jiang
authors.forename: Cheng-Long
authors.initials: CL
authors.lastname: Chuang
authors.forename: Ming-Tsung
authors.initials: MT
authors.lastname: Teng
mesh_terms: D000818:Animals; D053705:Capsule Endoscopes; D053704:Capsule Endoscopy / Q000295:instrumentation* / Q000379:methods*; D004574:Electromagnetic Fields; D004867:Equipment Design; D005240:Feasibility Studies; D005773:Gastroscopy / Q000295:instrumentation* / Q000379:methods*; D006801:Humans; D008954:Models, Biological; D013270:Stomach / Q000033:anatomy & histology / Q000601:surgery; D013552:Swine; D019415:Torque