title: [Liver parameters in intensive care medicine].
abstract: Elevated liver function tests in ICU-bound patients are associated with a greater risk of mor-tality. Chronic liver diseases as well as acute events and complications of therapy are among the causes. The disorder could further be investigated by assessment of liver cell integrity markers (AST, ALT and GLDH), cholestasis parameters -(bilirubin, GGT, ALP) and liver synthethic function (albumin, coagulation profile). Ultrasound and elastography are cheap and mobile options to evaluate chronic liver disease, cholestasis or perfusion of the liver. The interpretation of the results should include the medical history on the ICU. Liver injury could be due to septic or isch-aemic complications as well as toxic side effects or parenteral nutrition. The main therapeutic option is to identify the cause of the liver dysfuntion and to eliminate it as far as possible.
authors.affiliation: Universitätsklinikum Essen, Abteilung für Gastroenterologie und Hepatologie, Essen, Deutschland.
authors.forename: V
authors.initials: V
authors.lastname: Penndorf
authors.affiliation: Universitätsklinikum Essen, Abteilung für Allgemein-, Viszeral- und Transplantationschirurgie, Essen, Deutschland.
authors.forename: F
authors.initials: F
authors.lastname: Saner
authors.affiliation: Universitätsklinikum Essen, Abteilung für Gastroenterologie und Hepatologie, Essen, Deutschland.
authors.forename: G
authors.initials: G
authors.lastname: Gerken
authors.affiliation: Universitätsklinikum Essen, Abteilung für Gastroenterologie und Hepatologie, Essen, Deutschland.
authors.forename: A
authors.initials: A
authors.lastname: Canbay
mesh_terms: D018988:Bacterial Translocation; D056486:Chemical and Drug Induced Liver Injury / Q000175:diagnosis / Q000209:etiology; D015209:Cholangitis, Sclerosing / Q000175:diagnosis / Q000209:etiology; D002779:Cholestasis / Q000175:diagnosis / Q000209:etiology; D003422:Critical Care; D003937:Diagnosis, Differential; D054459:Elasticity Imaging Techniques; D058625:End Stage Liver Disease / Q000175:diagnosis / Q000209:etiology; D006801:Humans; D007511:Ischemia / Q000175:diagnosis / Q000209:etiology; D008099:Liver / Q000098:blood supply / Q000473:pathology; D008107:Liver Diseases / Q000175:diagnosis* / Q000209:etiology; D017114:Liver Failure, Acute / Q000175:diagnosis / Q000209:etiology; D008111:Liver Function Tests; D008279:Magnetic Resonance Imaging; D010289:Parenteral Nutrition, Total / Q000009:adverse effects; D012307:Risk Factors; D014463:Ultrasonography; D018616:Ultrasonography, Doppler, Duplex