title: Treating desmopressin-induced hyponatremia: a case using hypertonic saline.
abstract: Desmopressin acetate (DDAVP), a medication used in the treatment of bleeding and polyuric disorders, has the potential to cause hyponatremia when free water is not appropriately restricted with its use. This free water retention is reversible when DDAVP is discontinued. We report a case of symptomatic DDAVP-induced hyponatremia in which discontinuation of DDAVP led to a rapid increase of serum sodium. In order to prevent rapid free water excretion, DDAVP and hypertonic saline were used concurrently. With close monitoring, this can be an effective treatment strategy in patients with DDAVP-induced hyponatremia.
authors.forename: Shayan
authors.initials: S
authors.lastname: Shirazian
authors.forename: Nicole
authors.initials: N
authors.lastname: Ali
authors.forename: Steven
authors.initials: S
authors.lastname: Fishbane
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003894:Deamino Arginine Vasopressin / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007010:Hyponatremia / Q000139:chemically induced* / Q000188:drug therapy; D012462:Saline Solution, Hypertonic / Q000627:therapeutic use*
chemical_list: D012462:Saline Solution, Hypertonic; D003894:Deamino Arginine Vasopressin