title: Click-functionalized compact quantum dots protected by multidentate-imidazole ligands: conjugation-ready nanotags for living-virus labeling and imaging.
abstract: We synthesized a new class of mutifunctional multidentate-imidazole polymer ligands by one-step reaction to produce conjugation-ready QDs with great stability and compact size. Furthermore, combined with strain-promoted click chemistry, we developed a general strategy for efficient labeling of living-viruses with QD probes.
authors.affiliation: CAS Key Laboratory of Health Informatics, Institute of Biomedicine and Biotechnology, Chinese Academy of Sciences, Shenzhen, PR China.
authors.forename: Pengfei
authors.initials: P
authors.lastname: Zhang
authors.forename: Shuhui
authors.initials: S
authors.lastname: Liu
authors.forename: Duyang
authors.initials: D
authors.lastname: Gao
authors.forename: Dehong
authors.initials: D
authors.lastname: Hu
authors.forename: Ping
authors.initials: P
authors.lastname: Gong
authors.forename: Zonghai
authors.initials: Z
authors.lastname: Sheng
authors.forename: Jizhe
authors.initials: J
authors.lastname: Deng
authors.forename: Yifan
authors.initials: Y
authors.lastname: Ma
authors.forename: Lintao
authors.initials: L
authors.lastname: Cai
mesh_terms: D000818:Animals; D002460:Cell Line; D049109:Cell Proliferation; D057930:Click Chemistry; D005456:Fluorescent Dyes / Q000737:chemistry*; D006801:Humans; D057446:Hydrodynamics; D007093:Imidazoles / Q000737:chemistry*; D008024:Ligands; D008856:Microscopy, Fluorescence / Q000379:methods; D008958:Models, Molecular; D045663:Quantum Dots; D053586:Virus Internalization; D018406:Virus Physiological Phenomena; D014780:Viruses / Q000302:isolation & purification* / Q000648:ultrastructure
chemical_list: D005456:Fluorescent Dyes; D007093:Imidazoles; D008024:Ligands