title: Selective oxidative decarboxylation of amino acids to produce industrially relevant nitriles by vanadium chloroperoxidase.
abstract: Industrial nitriles from biomass: Vanadium-chloroperoxidase is successfully used to transform selectively glutamic acid into 3-cyanopropanoic acid, a key intermediate for the synthesis of bio-succinonitrile and bio-acrylonitrile, by using a catalytic amount of a halide salt. This clean oxidative decarboxylation can be applied to mixtures of amino acids obtained from plant waste streams, leading to easily separable nitriles.
authors.affiliation: Politehnica University of Timisoara, Industrial Chemistry and Environmental Engineering Faculty, Piata Victoriei 2, 300006 Timisoara, Romania.
authors.forename: Andrada
authors.initials: A
authors.lastname: But
authors.forename: Jérôme
authors.initials: J
authors.lastname: Le Nôtre
authors.forename: Elinor L
authors.initials: EL
authors.lastname: Scott
authors.forename: Ron
authors.initials: R
authors.lastname: Wever
authors.forename: Johan P M
authors.initials: JP
authors.lastname: Sanders
mesh_terms: D001203:Ascomycota / Q000201:enzymology; D002711:Chloride Peroxidase / Q000378:metabolism*; D018698:Glutamic Acid / Q000737:chemistry*; D006861:Hydrogen Peroxide / Q000737:chemistry; D007221:Industry; D009570:Nitriles / Q000737:chemistry*; D010084:Oxidation-Reduction; D013379:Substrate Specificity
chemical_list: D009570:Nitriles; D018698:Glutamic Acid; D006861:Hydrogen Peroxide; C418625:vanadium chloroperoxidase; D002711:Chloride Peroxidase