title: A high prevalence of carotid artery stenosis in male patients older than 65 years, irrespective of presenting clinical manifestation of atherosclerotic diseases.
abstract: This study investigated the prevalence of carotid artery stenosis (CS) and the association with various risk factors in male patients (>65 years) diagnosed with cardiovascular diseases. Duplex sonography of the carotid arteries was performed in 434 of 473 eligible patients of whom 118 (27.8%) patients had significant CS ≥50%. The prevalence and severity of CS did not differ between patients who presented with neurological symptoms or acute coronary syndrome/peripheral artery disease (30.8% vs 25.9%, respectively). Among patients with CS, a higher rate of current smoking, a higher systolic blood pressure, and a lower glomerular filtration rate were observed compared with patients without CS. A history of coronary artery bypass graft was a significant predictor of the presence of CS (P = .003, odds ratio [OR] = 2.70 [1.40-5.19]). The prevalence of CS in elderly males with manifest atherosclerotic disease is high, irrespective of presenting clinical manifestation.
authors.affiliation: Department of General Internal Medicine, Radboud University, Medical Centre Nijmegen, The Netherlands.
authors.forename: Seyyed Mohammad Reza
authors.initials: SM
authors.lastname: Kazemi-Bajestani
authors.forename: Maureen
authors.initials: M
authors.lastname: van der Vlugt
authors.forename: Frank-Erik
authors.initials: FE
authors.lastname: de Leeuw
authors.forename: Jan D
authors.initials: JD
authors.lastname: Blankensteijn
authors.forename: Sebastian J H
authors.initials: SJ
authors.lastname: Bredie
mesh_terms: D054058:Acute Coronary Syndrome / Q000453:epidemiology; D000367:Age Factors; D000368:Aged; D001794:Blood Pressure; D016893:Carotid Stenosis / Q000000981:diagnostic imaging / Q000453:epidemiology* / Q000503:physiopathology; D016009:Chi-Square Distribution; D005919:Glomerular Filtration Rate; D006801:Humans; D006973:Hypertension / Q000453:epidemiology / Q000503:physiopathology; D002546:Ischemic Attack, Transient / Q000453:epidemiology; D007668:Kidney / Q000503:physiopathology; D007674:Kidney Diseases / Q000453:epidemiology / Q000503:physiopathology; D016015:Logistic Models; D008297:Male; D009426:Netherlands / Q000453:epidemiology; D016017:Odds Ratio; D058729:Peripheral Arterial Disease / Q000453:epidemiology; D011237:Predictive Value of Tests; D015995:Prevalence; D012307:Risk Factors; D012720:Severity of Illness Index; D012737:Sex Factors; D012907:Smoking / Q000009:adverse effects / Q000453:epidemiology; D020521:Stroke / Q000453:epidemiology; D018616:Ultrasonography, Doppler, Duplex