title: Differences in body fat distribution assessed by ultrasonography in patients receiving antiretroviral drugs.
abstract: OBJECTIVE
  This study aimed to evaluate the body fat content of HIV patients according to the duration of antiretroviral therapy use (DURARV), < 1 year and > 1 year.
  
  
  METHODS
  Multiple linear regression was used to investigate the association between ultrasonographic variables of body fat compartments (BFCs) of the face, arm, subcutaneous and visceral abdomen, and the following explanatory variables: gender, age, BMI, and DURARV.
  
  
  RESULTS
  Of all patients (187), 102 of them with DURARV > 1 year were suffering from HIV-related lipodystrophy (HIV-LD), diagnosed through clinical questionnaires. Those with DURARV < 1 year (n = 85, = 46%) did not have HIV-LD. Regarding the visceral compartment, the difference between those with DURARV > 1 year and < 1 year was 11 mm of additional fat content in those with DURARV > 1 year. Women had more fat than men in all peripheral BFCs, while men had 7.2 mm more visceral fat than women, on average.
  
  
  CONCLUSIONS
  Ultrasonography is a method capable of measuring the thickness of BFCs and is applicable to clinical practice to diagnose HIV-LD.
authors.affiliation: Escola de Saúde Pública Sérgio Arouca (ENSP), Fundação Oswaldo Cruz (Fiocruz), Brazil. dariohart@terra.com.br
authors.forename: Dario Jose Hart Pontes
authors.initials: DJ
authors.lastname: Signorini
authors.forename: Ana Maria Schmidt de
authors.initials: AM
authors.lastname: Oliveira Netto
authors.forename: Michelle Carreira Miranda
authors.initials: MC
authors.lastname: Monteiro
authors.forename: Dario Hart
authors.initials: DH
authors.lastname: Signorini
authors.forename: Cláudia Torres
authors.initials: CT
authors.lastname: Codeço
authors.forename: Francisco I
authors.initials: FI
authors.lastname: Bastos
authors.forename: Sergio
authors.initials: S
authors.lastname: Gabbay
authors.forename: Marion de Fátima Castro de
authors.initials: Mde F
authors.lastname: Andrade
mesh_terms: D000328:Adult; D044966:Anti-Retroviral Agents / Q000627:therapeutic use*; D023241:Antiretroviral Therapy, Highly Active; D050218:Body Fat Distribution; D005260:Female; D039682:HIV-Associated Lipodystrophy Syndrome / Q000000981:diagnostic imaging* / Q000188:drug therapy; D006801:Humans; D016014:Linear Models; D008297:Male; D012737:Sex Factors; D012885:Skinfold Thickness; D014463:Ultrasonography
chemical_list: D044966:Anti-Retroviral Agents