title: Sialadenosis in dogs.
abstract: OBJECTIVE
  To determine clinical findings, cytologic and histologic characteristics of salivary glands, and response to treatment with phenobarbital in dogs with clinical signs typical of sialadenosis.
  
  
  METHODS
  Prospective study.
  
  
  METHODS
  13 dogs with enlarged salivary glands.
  
  
  METHODS
  Data were collected from dogs with clinical signs attributable to enlarged salivary glands. Salivary gland biopsy and cytologic specimens were examined. Dogs were treated with phenobarbital and monitored for response to treatment.
  
  
  RESULTS
  Clinical signs commonly associated with sialadenosis included retching and gulping. Substantial cellular changes were not detected by histologic or cytologic examination of enlarged salivary glands. Response to treatment with phenobarbital was rapid, although most dogs required continuous treatment to prevent recurrence of clinical signs.
  
  
  CONCLUSIONS
  Sialadenosis is a condition of unknown cause that may have been underdiagnosed in dogs. Criteria for diagnosis include typical clinical signs, enlarged salivary glands, and lack of substantial microscopic lesions. Response to treatment with phenobarbital is rapid.
authors.affiliation: Animal Medical Centre Referral Services, 511 Wilbraham Rd, Chorlton, Manchester M21 0UB, England.
authors.forename: P
authors.initials: P
authors.lastname: Boydell
authors.forename: R
authors.initials: R
authors.lastname: Pike
authors.forename: D
authors.initials: D
authors.lastname: Crossley
authors.forename: T
authors.initials: T
authors.lastname: Whitbread
mesh_terms: D000818:Animals; D004283:Dog Diseases / Q000473:pathology*; D004285:Dogs; D018757:GABA Modulators / Q000008:administration & dosage / Q000627:therapeutic use; D010634:Phenobarbital / Q000008:administration & dosage / Q000627:therapeutic use; D012469:Salivary Glands / Q000473:pathology; D012793:Sialadenitis / Q000473:pathology / Q000662:veterinary*
chemical_list: D018757:GABA Modulators; D010634:Phenobarbital