title: Repo-Man-PP1: a link between chromatin remodelling and nuclear envelope reassembly.
abstract: Coordination of late mitotic events is crucial for the maintenance of genome stability and for the control of gene expression after cell division. Reversible protein phosphorylation regulates this process by de-phosphorylation of mitotic phospho-proteins in a sequential and coordinated manner: this allows an orderly sequence of events to take place during mitotic exit. We have identified Repo-Man/PP1 as a phosphatase complex that regulates temporally and spatially chromatin re-organization and nuclear envelope re-formation during anaphase-telophase.
authors.affiliation: Wellcome Trust Centre for Cell Biology, Institute of Cell Biology, University of Edinburgh, Edinburgh, UK. P.Vagnarelli@ed.ac.uk
authors.forename: Paola
authors.initials: P
authors.lastname: Vagnarelli
authors.forename: William C
authors.initials: WC
authors.lastname: Earnshaw
mesh_terms: D000705:Anaphase; D042002:Chromatin Assembly and Disassembly; D009685:Nuclear Envelope / Q000378:metabolism*; D009687:Nuclear Proteins / Q000378:metabolism*; D054645:Protein Phosphatase 1 / Q000378:metabolism*; D013692:Telophase
chemical_list: D009687:Nuclear Proteins; D054645:Protein Phosphatase 1