title: The NIST radioactivity measurement assurance program for the radiopharmaceutical industry.
abstract: The National Institute of Standards and Technology (NIST) maintains a program for the establishment and dissemination of activity measurement standards in nuclear medicine. These standards are disseminated through Standard Reference Materials (SRMs), Calibration Services, radionuclide calibrator settings, and the NIST Radioactivity Measurement Assurance Program (NRMAP, formerly the NEI/NIST MAP). The MAP for the radiopharmaceutical industry is described here. Consolidated results show that, for over 3600 comparisons, 96% of the participants' results differed from that of NIST by less than 10%, with 98% being less than 20%. Individual radionuclide results are presented from 214 to 439 comparisons, per radionuclide, for (67)Ga, (90)Y, (99m)Tc, (99)Mo, (111)In, (125)I, (131)I, and (201)Tl. The percentage of participants results within 10% of NIST ranges from 88% to 98%.
authors.affiliation: Physical Measurement Laboratory, National Institute of Standards and Technology, 100 Bureau Dr., Gaithersburg, MD 20899, USA. jeffrey.cessna@nist.gov
authors.forename: Jeffrey T
authors.initials: JT
authors.lastname: Cessna
authors.forename: Daniel B
authors.initials: DB
authors.lastname: Golas
mesh_terms: D004345:Drug Industry / Q000592:standards*; D006078:Government Programs; D011785:Quality Assurance, Health Care / Q000592:standards*; D011829:Radiation Dosage; D011874:Radiometry / Q000592:standards*; D019275:Radiopharmaceuticals / Q000032:analysis* / Q000592:standards*; D012015:Reference Standards; D012016:Reference Values; D014481:United States
chemical_list: D019275:Radiopharmaceuticals