title: Low 25-hydroxyvitamin D level and adiponectin is associated with insulin sensitivity in large gestational age infants.
abstract: OBJECTIVE
  To investigate the relationship between adipokines (visfatin, adiponectin) and 25-hydroxyvitamin D (25(OH)D), and markers of insulin sensitivity in large for gestational age (LGA) infants.
  
  
  METHODS
  Forty LGA infants (25 LGA born to diabetic mothers and 15 LGA born to non-diabetic mothers) and 34 appropriate for gestational age (AGA) infants were recruited.
  
  
  RESULTS
  FGIR, QUICK-I, adiponectin and 25(OH)D levels were significantly lower in LGA with diabetic mother group than AGA and LGA with non-diabetic mother group. HOMA-IR, fasting insulin, visfatin and parathormone (PTH) levels were significantly higher in LGA with diabetic mother group than AGA and LGA with non-diabetic mother group.
  
  
  CONCLUSIONS
  Based on the findings of this study, visfatin, adiponectin and 25(OH)D levels can be used as specific markers for insulin sensitivity and may help advance new therapies for glucose intolerance spectrum.
authors.affiliation: Department of Pediatrics, Division of Neonatology, GATA Medical Faculty, 34090 Istanbul, Turkey. ferhat_cocuk@hotmail.com
authors.forename: Ferhat
authors.initials: F
authors.lastname: Cekmez
authors.forename: Gokhan
authors.initials: G
authors.lastname: Aydemir
authors.forename: Secil
authors.initials: S
authors.lastname: Aydinoz
authors.forename: Ozgur
authors.initials: O
authors.lastname: Pirgon
authors.forename: F Alparslan
authors.initials: FA
authors.lastname: Genc
authors.forename: Turan
authors.initials: T
authors.lastname: Tunc
authors.forename: Serdar Umit
authors.initials: SU
authors.lastname: Sarici
mesh_terms: D052242:Adiponectin / Q000097:blood*; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D007333:Insulin Resistance; D014807:Vitamin D / Q000031:analogs & derivatives* / Q000097:blood
chemical_list: D052242:Adiponectin; D014807:Vitamin D; C104450:25-hydroxyvitamin D