title: Dummy molecularly imprinted solid-phase extraction for selective determination of five phthalate esters in plastic bottled functional beverages.
abstract: In this paper, a highly selective sample cleanup procedure combing dummy molecular imprinting and solid-phase extraction (DMI-SPE) was developed for the simultaneous isolation and determination of five phthalate esters in plastic bottled beverages. The new imprinted microspheres were synthesized via precipitation polymerization using diisononyl phthalate as a dummy template that showed high selectivity and affinity to the five kinds of phthalate esters and were successfully applied as selective sorbents of DMI-SPE for the simultaneous determination of the phthalate esters from plastic bottled beverages. Good linearity was obtained in a range of 5.0-750.0 μg/L, and the average recoveries of the five phthalate esters at three spiked levels ranged from 84.3 to 96.2% with the relative standard deviations less than 5.49%. The developed extraction protocol eliminated the effect of template leakage on quantitative analysis and could be applied for the determination of phthalate esters in complicated functional beverages products.
authors.affiliation: Key Laboratory of Pharmaceutical Quality Control of Hebei Province & College of Pharmacy, Hebei University, Baoding, China. yanhy@hbu.edu.cn
authors.forename: Hongyuan
authors.initials: H
authors.lastname: Yan
authors.forename: Xiaoling
authors.initials: X
authors.lastname: Cheng
authors.forename: Gengliang
authors.initials: G
authors.lastname: Yang
mesh_terms: D000327:Adsorption; D001628:Beverages / Q000032:analysis*; D002851:Chromatography, High Pressure Liquid; D004952:Esters / Q000032:analysis / Q000737:chemistry* / Q000302:isolation & purification; D054802:Molecular Imprinting; D010795:Phthalic Acids / Q000032:analysis / Q000737:chemistry* / Q000302:isolation & purification; D011108:Polymers / Q000138:chemical synthesis / Q000737:chemistry*; D052616:Solid Phase Extraction / Q000295:instrumentation / Q000379:methods*
chemical_list: D004952:Esters; D010795:Phthalic Acids; D011108:Polymers; C032279:phthalic acid