title: Irritable bowel syndrome, gastro-oesophageal reflux disease and dyspepsia: overlap analysis using loglinear models.
abstract: OBJECTIVE
  Irritable bowel syndrome (IBS), gastro-oesophageal reflux disease (GERD) and dyspepsia are three most important gastrointestinal disorders which occur frequently together in patients. This study aims to assess the association between IBS, GERD and dyspepsia by using loglinear model analysis.
  
  
  METHODS
  This cross-sectional household survey, the purpose of which was to find the prevalence of gastrointestinal symptoms, disorders and the related factors, has been done from May 2006 to December 2007 in Tehran province, Iran. Subjects were interviewed by trained personnel. GERD was diagnosed as the experience of heartburn and/or acid regurgitation at least once a week for the last 3 months. IBS and dyspepsia were diagnosed according to the Rome III criteria. Loglinear models were applied to investigate the simultaneous association between IBS, GERD and dyspepsia.
  
  
  RESULTS
  77.9% of IBS patients had dyspepsia symptoms and 74.7% had GERD symptoms as well at the same time. As for the other two symptoms, 66% of GERD patients were also suffering from dyspepsia.
  
  
  CONCLUSIONS
  These three symptoms frequently overlap; the overlap is systematic and not by chance or random.
authors.affiliation: Research Center for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Science, Tehran, Iran.
authors.forename: Asma
authors.initials: A
authors.lastname: Pourhoseingholi
authors.forename: Mohsen
authors.initials: M
authors.lastname: Vahedi
authors.forename: Mohamad Amin
authors.initials: MA
authors.lastname: Pourhoseingholi
authors.forename: Sara
authors.initials: S
authors.lastname: Ashtari
authors.forename: Bijan
authors.initials: B
authors.lastname: Moghimi-Dehkordi
authors.forename: Azadeh
authors.initials: A
authors.lastname: Safaee
authors.forename: Mohamad Reza
authors.initials: MR
authors.lastname: Zali
mesh_terms: D000328:Adult; D003430:Cross-Sectional Studies; D004415:Dyspepsia / Q000150:complications* / Q000453:epidemiology; D005260:Female; D005764:Gastroesophageal Reflux / Q000150:complications* / Q000453:epidemiology; D006306:Health Surveys; D006801:Humans; D007492:Iran / Q000453:epidemiology; D043183:Irritable Bowel Syndrome / Q000150:complications* / Q000453:epidemiology; D016014:Linear Models; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D011795:Surveys and Questionnaires