title: Cytotoxic effect of some medicinal plants from Asteraceae family on J-45.01 leukemic cell line--pilot study.
abstract: In this study the in vitro cytotoxic properties of ethanol extracts from the herbs, inflorescents and roots of selected Asteraceae species: Arctium lappa, Artemisia absinthium, Calendula officinalis, Centaurea cyanus, Tanacetum vulgare and Tragopogon pratensis on J-45.01 human acute T leukemia cell line was examined. All tested samples possess antileukemic properties and induce cells death via apoptosis. The correlation between antileukemic activity and total polyphenol content was determined.
authors.affiliation: Department of Pharmaceutical Botany, Medical University, 20-093 Lublin, Poland. m.wegiera@am.lublin.pl
authors.forename: Magdalena
authors.initials: M
authors.lastname: Wegiera
authors.forename: Helena D
authors.initials: HD
authors.lastname: Smolarz
authors.forename: Marcin
authors.initials: M
authors.lastname: Jedruch
authors.forename: Magdalena
authors.initials: M
authors.lastname: Korczak
authors.forename: Kamila
authors.initials: K
authors.lastname: Koproń
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000494:pharmacology*; D017209:Apoptosis / Q000187:drug effects; D019659:Asteraceae / Q000737:chemistry; D006801:Humans; D019169:Jurkat Cells; D010865:Pilot Projects; D010936:Plant Extracts / Q000494:pharmacology*; D010946:Plants, Medicinal / Q000737:chemistry
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D010936:Plant Extracts