title: Chorioretinal lesions in mothers of children with congenital toxoplasmosis in the National Collaborative Chicago-based, Congenital Toxoplasmosis Study.
abstract: AIMS: To determine whether mothers of children with congenital toxoplasmosis have chorioretinal lesions consistent with toxoplasmosis.  METHODS: Prospective cohort study. Ophthalmologists in our study have examined 173 children with congenital toxoplasmosis in a hospital outpatient setting. These children were referred to us by their primary care physicians. One hundred and thirty mothers of these children had retina examinations of both eyes at least once. Main outcome measure was lesion(s) consistent with ocular toxoplasmosis.  RESULTS: Of 130 mothers examined between 1991-2005, 10 (7.7%, 95% Confidence Interval 3.8%, 13.7%) had chorioretinal lesions which likely represent resolved toxoplasmic chorioretinitis. Most of these were small peripheral chorioretinal lesions. None reactivated between 1991-2005.  CONCLUSIONS: Chorioretinal lesions consistent with quiescent ocular toxoplasmosis occur in mothers of children with congenital toxoplasmosis in the United States.
authors.affiliation: Department of Ophthalmology and Visual Sciences, The University of Chicago, Chicago, IL.
authors.forename: A Gwendolyn
authors.initials: AG
authors.lastname: Noble
authors.forename: Paul
authors.initials: P
authors.lastname: Latkany
authors.forename: Jaroslaw
authors.initials: J
authors.lastname: Kusmierczyk
authors.forename: Marilyn
authors.initials: M
authors.lastname: Mets
authors.forename: Peter
authors.initials: P
authors.lastname: Rabiah
authors.forename: Kenneth
authors.initials: K
authors.lastname: Boyer
authors.forename: Jessica
authors.initials: J
authors.lastname: Jalbrzikowski
authors.forename: Kristen
authors.initials: K
authors.lastname: Wroblewski
authors.forename: Theodore
authors.initials: T
authors.lastname: Karrison
authors.forename: Charles N
authors.initials: CN
authors.lastname: Swisher
authors.forename: William F
authors.initials: WF
authors.lastname: Mieler
authors.forename: Paul
authors.initials: P
authors.lastname: Meier
authors.forename: Rima
authors.initials: R
authors.lastname: McLeod