title: Myocardial blood flow quantification from MRI by deconvolution using an exponential approximation basis.
abstract: We have evaluated the use of deconvolution using an exponential approximation basis for the quantification of myocardial blood flow from perfusion cardiovascular magnetic resonance. Our experiments, based on simulated signal intensity curves, phantom acquisitions, and clinical image data, indicate that exponential deconvolution allows for accurate quantification of myocardial blood flow. Together with automated respiratory motion correction myocardial contour delineation, the exponential deconvolution enables efficient and reproducible quantification of myocardial blood flow in clinical routine.
authors.affiliation: Imaging Systems—MR, Philips Healthcare, Best 5684 PC, Netherlands. gilion.hautvast@philips.com
authors.forename: Gilion
authors.initials: G
authors.lastname: Hautvast
authors.forename: Amedeo
authors.initials: A
authors.lastname: Chiribiri
authors.forename: Niloufar
authors.initials: N
authors.lastname: Zarinabad
authors.forename: Andreas
authors.initials: A
authors.lastname: Schuster
authors.forename: Marcel
authors.initials: M
authors.lastname: Breeuwer
authors.forename: Eike
authors.initials: E
authors.lastname: Nagel
mesh_terms: D000465:Algorithms; D003326:Coronary Circulation / Q000502:physiology*; D006439:Hemodynamics / Q000502:physiology*; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D018810:Magnetic Resonance Angiography / Q000379:methods*; D008955:Models, Cardiovascular; D019047:Phantoms, Imaging