title: GPSy: a cross-species gene prioritization system for conserved biological processes--application in male gamete development.
abstract: We present gene prioritization system (GPSy), a cross-species gene prioritization system that facilitates the arduous but critical task of prioritizing genes for follow-up functional analyses. GPSy's modular design with regard to species, data sets and scoring strategies enables users to formulate queries in a highly flexible manner. Currently, the system encompasses 20 topics related to conserved biological processes including male gamete development discussed in this article. The web server-based tool is freely available at http://gpsy.genouest.org.
authors.affiliation: Inserm Unité 1085-Irset, France.
authors.forename: Ramona
authors.initials: R
authors.lastname: Britto
authors.forename: Olivier
authors.initials: O
authors.lastname: Sallou
authors.forename: Olivier
authors.initials: O
authors.lastname: Collin
authors.forename: Grégoire
authors.initials: G
authors.lastname: Michaux
authors.forename: Michael
authors.initials: M
authors.lastname: Primig
authors.forename: Frédéric
authors.initials: F
authors.lastname: Chalmel
mesh_terms: D000818:Animals; D017173:Caenorhabditis elegans / Q000235:genetics / Q000502:physiology; D015870:Gene Expression; D005796:Genes; D023281:Genomics / Q000379:methods; D020407:Internet; D008297:Male; D023421:Models, Animal; D058977:Molecular Sequence Annotation; D034622:RNA Interference; D012984:Software; D013091:Spermatogenesis / Q000235:genetics*