title: [Anti-hepatitis B virus drugs].
abstract: Nucleoside and nucleotide analogues are potent oral inhibitors for hepatitis B virus proliferation. In Japan, we can use lamivudine, adefovir and entecavir for hepatitis B at present. Entecavir is a first choice drug because it has stronger anti-viral potency and less induction for drug-resistance viruses than other drugs. Using these drugs, we can now control hepatitis caused by hepatitis B virus on treatment in a majority of patients. Next goal will be cure of hepatitis B, but there still remains further progress.
authors.affiliation: Department of Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine.
authors.forename: Masahito
authors.initials: M
authors.lastname: Minami
mesh_terms: D000998:Antiviral Agents / Q000494:pharmacology* / Q000627:therapeutic use; D006147:Guanine / Q000031:analogs & derivatives / Q000627:therapeutic use; D006509:Hepatitis B / Q000188:drug therapy*; D006515:Hepatitis B virus / Q000187:drug effects*; D006801:Humans
chemical_list: D000998:Antiviral Agents; C413685:entecavir; D006147:Guanine