title: [A prospective study on the association between dynamic change of waist circumference and incident hypertension].
abstract: OBJECTIVE
  To study the impact on dynamic change of waist circumference (WC) through follow-up data on the incidence of hypertension in several cohort groups.
  
  
  METHODS
  In this prospective study, 2778 free-hypertension subjects were recruited from a program "Prevention of Multiple Metabolic disorders and metabolic syndrome (MS) in Jiangsu province" (PMMJS) to evaluate the risk of hypertension in relation to WC dynamic change on normal WC or abnormal obesity group. Dynamic change of WC was measured by WC D-value, which was expressed by data on the difference of WC between baseline and the first follow up. Study outcome was defined as incident hypertension during the first to the second follow up period in this study. The association between dynamic change of WC and incident hypertension was analyzed by using Cox proportional hazards regression model.
  
  
  RESULTS
  There were 2778 participants, 660 subjects developed hypertension during the follow-up, regardless of the normality of the baseline WC, the risk of hypertension increased across the tertiles of WC, while the incidence of hypertension was higher in non-control group than that in control group. In populations with abdominal obesity and normal WC at baseline, RRs (95%CI) of hypertension were 1.95 (1.19 - 3.19) and 2.38 (1.89 - 2.99) in subjects with abdominal obesity seen at the first follow up period, compared to subjects with normal WC in the same period. After adjustment for gender, age and other hypertension related risk factors, in populations with abdominal obesity and normal WC at baseline survey, RRs (95%CI) of hypertension were 4.36 (1.69 - 9.74) and 1.44 (1.03 - 2.35) respectively, for the non-control group.
  
  
  CONCLUSIONS
  WC dynamic change was associated with hypertension, WC control while WC reduction was important for early prevention on hypertension.
authors.affiliation: Department of Radiology & Public Health, Soochow University, Suzhou 215123, China.
authors.forename: Wen-shu
authors.initials: WS
authors.lastname: Luo
authors.forename: Zhi-rong
authors.initials: ZR
authors.lastname: Guo
authors.forename: Xiao-shu
authors.initials: XS
authors.lastname: Hu
authors.forename: Zheng-yuan
authors.initials: ZY
authors.lastname: Zhou
authors.forename: Ming
authors.initials: M
authors.lastname: Wu
authors.forename: Li-jun
authors.initials: LJ
authors.lastname: Zhang
authors.forename: Jing-chao
authors.initials: JC
authors.lastname: Liu
mesh_terms: D000328:Adult; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006973:Hypertension / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D016016:Proportional Hazards Models; D011446:Prospective Studies; D055105:Waist Circumference