title: Isolation and characterization of a Chinese strain of human enterovirus 74 from a healthy child in the Tibet Autonomous Region of China.
abstract: Human enterovirus 74 (HEV74) is a recently described serotype within the species Human enterovirus B (HEV-B). Few nucleotide sequences of HEV74 are available, and only one complete genome sequence (the prototype strain) has been published. In this study, we report the complete genome sequence of an HEV74 strain isolated from a healthy child during a stool survey in the Tibet Autonomous Region of China. The results indicated that HEV74 may be a prevalent and common enterovirus type, and that HEV74 is globally distributed, especially in Asia. Sequence analysis revealed high variability among HEV74 strains and indicated frequent recombination within HEV-B.
authors.affiliation: School of Life Science, Shanxi University, Taiyuan City, Shanxi Province, People's Republic of China.
authors.forename: Jitao
authors.initials: J
authors.lastname: Wang
authors.forename: Yong
authors.initials: Y
authors.lastname: Zhang
authors.forename: Mei
authors.initials: M
authors.lastname: Hong
authors.forename: Xiaolei
authors.initials: X
authors.lastname: Li
authors.forename: Shuangli
authors.initials: S
authors.lastname: Zhu
authors.forename: Dongmei
authors.initials: D
authors.lastname: Yan
authors.forename: Dongyan
authors.initials: D
authors.lastname: Wang
authors.forename: Hongqiu
authors.initials: H
authors.lastname: An
authors.lastname: Tsewang
authors.forename: Jianrong
authors.initials: J
authors.lastname: Han
authors.forename: Wenbo
authors.initials: W
authors.lastname: Xu
mesh_terms: D002648:Child; D029822:Enterovirus B, Human / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification*; D004769:Enterovirus Infections / Q000821:virology*; D005243:Feces / Q000821:virology; D016679:Genome, Viral; D006801:Humans; D017422:Sequence Analysis, DNA; D018609:Tibet; D015678:Viral Structural Proteins / Q000737:chemistry / Q000235:genetics
chemical_list: D015678:Viral Structural Proteins