title: Anti - diabetic activity of the seed kernel of syzygium cumini linn.
abstract: Syzygium cumini seed kernel (aqueous suspension) was screened for its antibiadetic activity at the dose levels of 1g., 2g., 4g and 6 g/kg body weight. 4g / kg dose level was found to exhibit maximum hypoglycaemic effect (42.64%) in rabbits, 3hr. after medication. Like Tolbutamide the drug may also be promoting endogenous release of insulin. An extra pancreatic site of action of the drug cannot be ruled out, since it produced a significant decrease in the blood sugar level (17.04%) in alloxan diabetic rats.
authors.affiliation: C D R S Pharmacological Unit, Medical College, Trivandrum, Kerala - 695 011, India.
authors.forename: R B
authors.initials: RB
authors.lastname: Nair
authors.forename: G
authors.initials: G
authors.lastname: Santhakumari