title: Integrated assessment techniques for linking kinematics, kinetics and muscle activation to early migration: a pilot study.
abstract: The goal of this pilot study was to develop and test an integrated method to assess kinematics, kinetics and muscle activation of total knee prostheses during dynamic activities, by integrating fluoroscopic measurements with force plate, electromyography and external motion registration measurements. Subsequently, this multi-instrumental analysis was then used to assess the relationship between kinematics, kinetics and muscle activation and early migration of the tibial component of total knee prostheses. This pilot study showed that it is feasible to integrate fluoroscopic, kinematic and kinetic measurements and relate findings to early migration data. Results showed that there might be an association between deviant kinematics and early migration in patients with a highly congruent mobile-bearing total knee prosthesis. Patients that showed high levels of coactivation, diverging axial rotations of the insert and a deviant pivot point showed increased migration and might be at higher risk for tibial component loosening. In the future, to confirm our findings, the same integrated measurements have to be performed in larger patient groups and different prosthesis designs.
authors.affiliation: Biomechanics and Imaging Group, Department of Orthopaedics, Leiden University Medical Center, Leiden PO box 9600, 2300 RC Leiden, The Netherlands. nienkew66@hotmail.com
authors.forename: Nienke
authors.initials: N
authors.lastname: Wolterbeek
authors.forename: Eric H
authors.initials: EH
authors.lastname: Garling
authors.forename: Henrica M J
authors.initials: HM
authors.lastname: van der Linden
authors.forename: Rob G H H
authors.initials: RG
authors.lastname: Nelissen
authors.forename: Edward R
authors.initials: ER
authors.lastname: Valstar
mesh_terms: D019645:Arthroplasty, Replacement, Knee / Q000534:rehabilitation*; D001696:Biomechanical Phenomena; D004576:Electromyography; D005069:Evaluation Studies as Topic; D005260:Female; D005471:Fluoroscopy; D006801:Humans; D007593:Joint Instability / Q000517:prevention & control; D007720:Knee Prosthesis; D008297:Male; D008875:Middle Aged; D009119:Muscle Contraction / Q000502:physiology*; D018482:Muscle, Skeletal / Q000502:physiology; D010865:Pilot Projects; D011184:Postoperative Period; D011474:Prosthesis Design; D011475:Prosthesis Failure; D016059:Range of Motion, Articular / Q000502:physiology*; D018570:Risk Assessment; D013314:Stress, Mechanical; D016474:Weight-Bearing