title: Hypertension in pregnancy:  is it time for a new approach to treatment?
abstract: Hypertensive disorders represent major causes of pregnancy-related maternal mortality worldwide. The current definition and treatment recommendations for elevated blood pressure (BP) during pregnancy in the United States have remained unchanged for many years, unlike the recommendations for hypertension treatment in the general population. Clinical studies have provided convincing evidence that women with hypertensive pregnancy disorders are at both immediate and long-term risk for cardiovascular complications; these findings suggest that consideration be given to lowering the presently recommended BP thresholds, both for the initiation of therapy and for therapeutic targets, and to simplifying the approach to the management of elevated BP in pregnancy. This review focuses on the current treatment strategies for hypertensive pregnancy disorders, new developments in the field of hypertension, in general, and in pregnant patients, in particular, and their potential impact on contemporary BP goals and the use of specific antihypertensive medications in pregnancy.
authors.affiliation: Department of Medicine/Cardiology, Yale University School of Medicine, New Haven, Connecticut, USA.
authors.forename: Marvin
authors.initials: M
authors.lastname: Moser
authors.forename: Catherine M
authors.initials: CM
authors.lastname: Brown
authors.forename: Carl H
authors.initials: CH
authors.lastname: Rose
authors.forename: Vesna D
authors.initials: VD
authors.lastname: Garovic
mesh_terms: D000959:Antihypertensive Agents / Q000627:therapeutic use; D001794:Blood Pressure; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000188:drug therapy* / Q000503:physiopathology; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000188:drug therapy* / Q000503:physiopathology
chemical_list: D000959:Antihypertensive Agents