title: Effects of green tea supplementation on elements, total antioxidants, lipids, and glucose values in the serum of obese patients.
abstract: The consumption of green tea has been associated with cardiovascular and metabolic diseases. There have been some studies on the influence of green tea on the mineral status of obese subjects, but they have not yielded conclusive results. The aim of the present study is to examine the effects of green tea extract on the mineral, body mass, lipid profile, glucose, and antioxidant status of obese patients. A randomized, double-blind, placebo-controlled study was conducted. Forty-six obese patients were randomly assigned to receive either 379 mg of green tea extract, or a placebo, daily for 3 months. At baseline, and after 3 months of treatment, the anthropometric parameters, blood pressure, and total antioxidant status were assessed, as were the levels of plasma lipids, glucose, calcium, magnesium, iron, zinc, and copper. We found that 3 months of green tea extract supplementation resulted in decreases in body mass index, waist circumference, and levels of total cholesterol, low-density cholesterol, and triglyceride. Increases in total antioxidant level and in zinc concentration in serum were also observed. Glucose and iron levels were lower in the green tea extract group than in the control, although HDL-cholesterol and magnesium were higher in the green tea extract group than in the placebo group. At baseline, a positive correlation was found between calcium and body mass index, as was a negative correlation between copper and triglycerides. After 3 months, a positive correlation between iron and body mass index and between magnesium and HDL-cholesterol, as well as a negative correlation between magnesium and glucose, were observed. The present findings demonstrate that green tea influences the body's mineral status. Moreover, the results of this study confirm the beneficial effects of green tea extract supplementation on body mass index, lipid profile, and total antioxidant status in patients with obesity.
authors.affiliation: Department of Human Nutrition and Hygiene, Poznan University of Life Sciences, Wojska Polskiego 31 Str, 60-624 Poznan, Poland. jsulibur@up.poznan.pl
authors.forename: Joanna
authors.initials: J
authors.lastname: Suliburska
authors.forename: Pawel
authors.initials: P
authors.lastname: Bogdanski
authors.forename: Monika
authors.initials: M
authors.lastname: Szulinska
authors.forename: Marta
authors.initials: M
authors.lastname: Stepien
authors.forename: Danuta
authors.initials: D
authors.lastname: Pupek-Musialik
authors.forename: Anna
authors.initials: A
authors.lastname: Jablecka
mesh_terms: D000328:Adult; D000975:Antioxidants / Q000378:metabolism*; D001786:Blood Glucose / Q000187:drug effects*; D002392:Catechin / Q000031:analogs & derivatives / Q000627:therapeutic use; D019587:Dietary Supplements; D005260:Female; D006801:Humans; D008055:Lipids / Q000097:blood*; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000178:diet therapy* / Q000378:metabolism*; D018384:Oxidative Stress / Q000187:drug effects; D013662:Tea
chemical_list: D000975:Antioxidants; D001786:Blood Glucose; D008055:Lipids; D013662:Tea; D002392:Catechin; C045651:epigallocatechin gallate