title: Neuropsychological outcome after extra-temporal epilepsy surgery.
abstract: BACKGROUND
  The neuropsychological results of temporal lobe epilepsy surgery are well reported in the literature. The aim of this study was to analyse the neuropsychological outcome in a consecutive series of patients with extra-temporal epilepsy.
  
  
  METHODS
  We retrospectively analysed the data of patients operated between 1996 and 2008 for extra-temporal epilepsy. Standard neuropsychological tests were applied. We assessed the neuropsychological outcome after surgery and the correlation of the neuropsychological outcome with (1) side and localisation of surgery, (2) Engel scale for seizure outcome and (3) timing of surgery.
  
  
  RESULTS
  Patients had a better neuropsychological outcome when undergoing non-frontal resection [χ2 (2) =6.66, p = 0.036]. Subjects who had undergone left or right resection showed no difference in outcome [χ2 (2) =0.533, p = 0.766]. The correlation between the Engel scale for seizure re-occurence and the neuropsychological scores showed only a tendency for better outcome (Spearman ρ = -0.437; p = 0.069). The global measure of change did not correlate significantly with delay of surgery (Spearman ρ = -0.163; p = 0.518).
  
  
  CONCLUSIONS
  Resective epilepsy surgery improves neuropsychological status outcome in patients with extra-temporal epilepsy even if the patient did not become seizure free. The outcome is better for non-frontal localisation.
authors.affiliation: Department of Neurosurgery, Geneva University Hospitals, Genève 14, Switzerland. yassine.elhassani@hcuge.ch
authors.forename: Yassine
authors.initials: Y
authors.lastname: El Hassani
authors.forename: Maryll
authors.initials: M
authors.lastname: Fournet
authors.forename: Shahan
authors.initials: S
authors.lastname: Momjian
authors.forename: Claudio
authors.initials: C
authors.lastname: Pollo
authors.forename: Margitta
authors.initials: M
authors.lastname: Seeck
authors.forename: Alan
authors.initials: A
authors.lastname: Pegna
authors.forename: Karl
authors.initials: K
authors.lastname: Schaller
mesh_terms: D000293:Adolescent; D000328:Adult; D038481:Anterior Temporal Lobectomy / Q000379:methods; D002648:Child; D004833:Epilepsy, Temporal Lobe / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D012189:Retrospective Studies; D012640:Seizures / Q000601:surgery; D016896:Treatment Outcome; D055815:Young Adult