title: Formation of tetrahydrocurcumin by reduction of curcumin with cultured plant cells of Marchantia polymorpha.
abstract: Cultured plant cells of Marchantia polymorpha, Nicotiana tabacum, Phytolacca americana, Catharanthus roseus, and Gossypium hirsutum were examined for their ability to reduce curcumin. Only M. polymorpha cells converted curcumin into tetrahydrocurcumin in 90% yield in one day. Time-course experiment revealed a two-step formation of tetrahydrocurcumin via dihydrocurcumin.
authors.affiliation: Department of Chemistry, Faculty of Medicine, Oita University, 1-1 Hasama-machi, Oita 879-5593, Japan. shimoda@med.oita-u.ac.jp
authors.forename: Kei
authors.initials: K
authors.lastname: Shimoda
authors.forename: Naoji
authors.initials: N
authors.lastname: Kubota
authors.forename: Hirotaka
authors.initials: H
authors.lastname: Hirano
authors.forename: Masahiro
authors.initials: M
authors.lastname: Matsumoto
authors.forename: Hatsuyuki
authors.initials: H
authors.lastname: Hamada
authors.forename: Hiroki
authors.initials: H
authors.lastname: Hamada
mesh_terms: D002478:Cells, Cultured; D003474:Curcumin / Q000031:analogs & derivatives* / Q000378:metabolism*; D047008:Marchantia / Q000166:cytology / Q000378:metabolism*
chemical_list: C096277:tetrahydrocurcumin; D003474:Curcumin