title: [Analysis on clinical characteristics, treatments and prognostic factors of head and neck non-Hodgkin's lymphoma].
abstract: To study the clinical characteristics, treatments and prognoses of the primary non-Hodgkin's lymphoma (NHL) in head and neck.
  
  
  
  Clinical manifestations and clinicopathology characteristics of 107 NHL patients in head and neck were analyzed retrospectively.
  
  
  
  The median age of patients with head and neck NHL was 54 years. The most commonly primary site was tonsil (29 cases, 27.10%), and the secondly primary site was nasal cavity (28 cases, 26.17%). The most common histologic subtype was diffuse large B cell lymphoma(46 cases, 42.99%), and the secondly one was NK/T cell lymphoma(24 cases, 22.43%). We found that the combination of rituximab was superior than that of chemotherapy alone. Prognosis depended on both IPI and histological subtype, and IPI was a more dangerous factor than histological subtype.
  
  
  
  The primary NHL is a common neoplasm in the head and neck region. Characteristic in age, primary site, histologic subtype, treatment and prognostic factors were helpful to understand and treat non-Hodgkin's lymphoma in head and neck.
authors.affiliation: Department of Otolaryngology, Ruijin Hospital,Shanghai Jiaotong University School of Medicine,Shanghai, 200025, China.
authors.forename: Jun
authors.initials: J
authors.lastname: Wang
authors.forename: Changping
authors.initials: CP
authors.lastname: Cai
authors.forename: Shifang
authors.initials: SF
authors.lastname: He
authors.forename: Shili
authors.initials: SL
authors.lastname: Wang
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D005260:Female; D006258:Head and Neck Neoplasms / Q000175:diagnosis* / Q000628:therapy*; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000175:diagnosis* / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012189:Retrospective Studies; D016896:Treatment Outcome; D055815:Young Adult