title: A case of resected synchronous multiple primary lung cancer comprising adenocarcinoma and carcinoid (cancer-in-cancer).
abstract: We performed surgical resection of synchronous multiple primary lung cancer, comprising adenocarcinoma and carcinoid components. The latter tumor was located within the central scar tissue formed by the adenocarcinoma (cancer-in-cancer). The patient was a 67-year-old Japanese woman who had a nodular lesion in the right S1 on chest computed tomography. Lung cancer was diagnosed intraoperatively by rapid needle aspiration cytology, and right upper lobectomy with mediastinal lymph node dissection was performed. Histological examination of the resected specimen revealed cancer-in-cancer, consisting of adenocarcinoma and a carcinoid tumor. The carcinoid component was localized within the central fibrous scar of the dominant adenocarcinoma component.
authors.affiliation: Department of Surgery, National Hospital Organization Omuta National Hospital, 1044-1 Tachibana, Ohumta, Fukuoka, Japan. nagam2@nifty.com
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Nagamatsu
authors.forename: Yasunori
authors.initials: Y
authors.lastname: Iwasaki
authors.forename: Harutaka
authors.initials: H
authors.lastname: Omura
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Kumazoe
authors.forename: Ryozo
authors.initials: R
authors.lastname: Hyashida
authors.forename: Kazuo
authors.initials: K
authors.lastname: Shirouzu
mesh_terms: D000230:Adenocarcinoma / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D000077192:Adenocarcinoma of Lung; D000368:Aged; D001707:Biopsy, Needle; D002276:Carcinoid Tumor / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D008197:Lymph Node Excision; D018198:Mixed Tumor, Malignant / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D009378:Neoplasms, Multiple Primary / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D011013:Pneumonectomy; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome