title: Sigpep: calculating unique peptide signature transition sets in a complete proteome background.
abstract: We have created a new software platform called sigpep that analyzes transition redundancy in selected reaction monitoring assays. Building on this platform, we also created a web application to generate transition sets with unique signatures for targeted peptides. The platform has been made available under the permissive Apache 2.0 open-source license, and the web application can be accessed from http://iomics.ugent.be/sigpep.
authors.affiliation: Department of Medical Protein Research, VIB, Ghent, Belgium.
authors.forename: Kenny
authors.initials: K
authors.lastname: Helsens
authors.forename: Michael
authors.initials: M
authors.lastname: Mueller
authors.forename: Niels
authors.initials: N
authors.lastname: Hulstaert
authors.forename: Lennart
authors.initials: L
authors.lastname: Martens
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D006801:Humans; D020407:Internet; D013058:Mass Spectrometry / Q000379:methods*; D008969:Molecular Sequence Data; D010455:Peptides / Q000032:analysis*; D020543:Proteome / Q000032:analysis*; D040901:Proteomics / Q000379:methods*; D012015:Reference Standards; D012984:Software; D014357:Trypsin / Q000737:chemistry
chemical_list: D010455:Peptides; D020543:Proteome; D014357:Trypsin