title: Stereoselective UV sensing of 1,2-diaminocyclohexane isomers based on ligand displacement with a diacridylnaphthalene N,N'-dioxide scandium complex.
abstract: Stereoselective displacement of diacridylnaphthalene N,N'-dioxide ligands, 1, from a scandium(III) complex can be used for quantitative detection of 1,2-diaminocyclohexane isomers. The diastereoselective sensing assay with Sc(syn-1)(2) shows excellent linearity between the sample de and the measured UV absorption change, and sensing of mixtures comprising both low and high de values gave results within 5% accuracy. All three stereoisomers of 1,2-diaminocyclohexane can be differentiated using Sc[anti-(-)-1](2) in the same ligand displacement assay.
authors.affiliation: Department of Chemistry, Georgetown University, Washington, DC 20057, United States.
authors.forename: Daniel P
authors.initials: DP
authors.lastname: Iwaniuk
authors.forename: Kimberly
authors.initials: K
authors.lastname: Yearick-Spangler
authors.forename: Christian
authors.initials: C
authors.lastname: Wolf
mesh_terms: D002384:Catalysis; D003514:Cyclohexylamines / Q000737:chemistry*; D007536:Isomerism; D008024:Ligands; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D012538:Scandium / Q000737:chemistry*; D013056:Spectrophotometry, Ultraviolet
chemical_list: D003514:Cyclohexylamines; D008024:Ligands; D009942:Organometallic Compounds; C574888:diacridylnaphthalene N,N'-dioxide scandium; C030435:1,2-cyclohexanediamine; D012538:Scandium