title: Essential oil of the leaves of Eugenia uniflora L.: antioxidant and antimicrobial properties.
abstract: Essential oil (EO) of the leaves of Eugenia uniflora L. (Brazilian cherry tree) was evaluated for its antioxidant, antibacterial and antifungal properties. The acute toxicity of the EO administered by oral route was also evaluated in mice. The EO exhibited antioxidant activity in the DPPH, ABTS and FRAP assays and reduced lipid peroxidation in the kidney of mice. The EO also showed antimicrobial activity against two important pathogenic bacteria, Staphylococcus aureus and Listeria monocytogenes, and against two fungi of the Candida species, C. lipolytica and C. guilliermondii. Acute administration of the EO by the oral route did not cause lethality or toxicological effects in mice. These findings suggest that the EO of the leaves of E. uniflora may have the potential for use in the pharmaceutical industry.
authors.affiliation: Faculdade de Agronomia Eliseu Maciel, Departamento de Ciência e Tecnologia Agroindustrial, Universidade Federal de Pelotas, Pelotas-RS, Brazil.
authors.forename: Francine Novack
authors.initials: FN
authors.lastname: Victoria
authors.forename: Eder João
authors.initials: EJ
authors.lastname: Lenardão
authors.forename: Lucielli
authors.initials: L
authors.lastname: Savegnago
authors.forename: Gelson
authors.initials: G
authors.lastname: Perin
authors.forename: Raquel Guimarães
authors.initials: RG
authors.lastname: Jacob
authors.forename: Diego
authors.initials: D
authors.lastname: Alves
authors.forename: Wladimir Padilha
authors.initials: WP
authors.lastname: da Silva
authors.forename: Amanda de Souza
authors.initials: Ade S
authors.lastname: da Motta
authors.forename: Patricia da Silva
authors.initials: Pda S
authors.lastname: Nascente
mesh_terms: D000818:Animals; D000890:Anti-Infective Agents / Q000494:pharmacology*; D000975:Antioxidants / Q000494:pharmacology*; D002175:Candida / Q000187:drug effects; D007928:Lethal Dose 50; D008089:Listeria monocytogenes / Q000187:drug effects; D051379:Mice; D008826:Microbial Sensitivity Tests; D009822:Oils, Volatile / Q000494:pharmacology*; D010936:Plant Extracts / Q000494:pharmacology*; D018515:Plant Leaves / Q000737:chemistry*; D013211:Staphylococcus aureus / Q000187:drug effects; D027842:Syzygium / Q000737:chemistry*
chemical_list: D000890:Anti-Infective Agents; D000975:Antioxidants; D009822:Oils, Volatile; D010936:Plant Extracts