title: Highly stereoselective synthesis of (Z)-1,2-dihaloalkenes by a Pd-catalyzed hydrohalogenation of alkynyl halides.
abstract: An unprecedented Pd-catalyzed hydrohalogenation of alkynyl halides for the regio- and stereoselective synthesis of (Z)-1,2-dihaloalkenes has been realized using [(allyl)PdCl](2) as the catalyst and cis,cis-1,5-cyclooctadiene as the ligand. The advantages of this protocol are well illustrated by the assembly of trisubstituted (Z)-enynes and multifunctional benzenes via iterative cross-coupling reactions or tandem Diels-Alder-aromatization reactions, respectively.
authors.affiliation: Department of Chemistry, Zhejiang Normal University, 688 Yingbin Road, Jinhua 321004, China. gangguo@zjnu.cn
authors.forename: Gangguo
authors.initials: G
authors.lastname: Zhu
authors.forename: Dongxu
authors.initials: D
authors.lastname: Chen
authors.forename: Yuyi
authors.initials: Y
authors.lastname: Wang
authors.forename: Renwei
authors.initials: R
authors.lastname: Zheng