title: Physicochemical properties and in vitro biocompatibility of a hydraulic calcium silicate/tricalcium aluminate cement for endodontic use.
abstract: This study sought to prepare a calcium silicate cement (CSC) with varying additions of tricalcium aluminate (Ca(3)Al(2)O(6), C(3)A), and to find an optimal amount of C(3)A by evaluating the effect of C(3)A on the physicochemical and in vitro biological properties of the CS/C(3)A cement. The results indicated that the addition of C(3)A into CSC reduced the setting time and improved the compressive strength especially at the early stage of setting. However, the 15% C(3)A was too much for the CS/C(3)A system and did harm to its strength development. Furthermore, the CS/C(3)A cement was bioactive and biocompatible in vitro, and had a stimulatory effect on the cell growth, when the content of C(3)A was 5 or 10%. When compared with the commercially available Dycal(®), the CS/C(3)A cement was notably more compatible with the human dental pulp cells. Therefore, the CS/C(3)A cement with 5-10% C(3)A produced the best compromise between setting and in vitro biological properties, and may be a promising candidate for endodontic use.
authors.affiliation: State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai, China.
authors.forename: Weining
authors.initials: W
authors.lastname: Liu
authors.forename: Weiwei
authors.initials: W
authors.lastname: Peng
authors.forename: Yaqin
authors.initials: Y
authors.lastname: Zhu
authors.forename: Jiang
authors.initials: J
authors.lastname: Chang
mesh_terms: D017607:Aluminum Compounds / Q000737:chemistry*; D017610:Calcium Compounds / Q000737:chemistry*; D002478:Cells, Cultured; D003738:Dental Cements / Q000737:chemistry*; D003782:Dental Pulp / Q000166:cytology*; D006801:Humans; D008422:Materials Testing; D017640:Silicates / Q000737:chemistry*
chemical_list: D017607:Aluminum Compounds; D017610:Calcium Compounds; D003738:Dental Cements; D017640:Silicates; C031293:calcium silicate