title: Case of peptide-YY-producing strumal carcinoid of the ovary: a case report and review.
abstract: Ovarian carcinoid is a rare tumor accounting for approximately 0.1% of all ovarian malignancies. We describe a case of peptide-YY-producing strumal carcinoid of the ovary associated with severe constipation. A 48-year-old woman was found to have a pelvic mass on ultrasonography when she visited her primary doctor for a health check-up. She was thus referred to our department. Magnetic resonance imaging revealed a solid right ovarian tumor 60 × 50 mm in size. The patient underwent a right adnexectomy and was histopathologically diagnosed as having strumal carcinoid of the ovary. On immunohistochemical examination, the tumor cells were positive for peptide YY. The patient's constipation resolved rapidly after surgery. Based on her clinical course, her constipation was considered to have been caused by the strumal carcinoid of the ovary. The clinical course of this case supports the previously recognized correlation between peptide-YY-producing ovarian carcinoid and constipation.
authors.affiliation: Department of Obstetrics and Gynecology, Iwate Medical University, Morioka, Iwate, Japan.
authors.forename: Eriko
authors.initials: E
authors.lastname: Takatori
authors.forename: Tadahiro
authors.initials: T
authors.lastname: Shoji
authors.forename: Jiyu
authors.initials: J
authors.lastname: Miura
authors.forename: Satoshi
authors.initials: S
authors.lastname: Takeuchi
authors.forename: Akira
authors.initials: A
authors.lastname: Yoshizaki
authors.forename: Toru
authors.initials: T
authors.lastname: Sugiyama
mesh_terms: D002276:Carcinoid Tumor / Q000378:metabolism / Q000503:physiopathology* / Q000601:surgery; D003248:Constipation / Q000209:etiology* / Q000503:physiopathology / Q000517:prevention & control; D005260:Female; D006801:Humans; D008875:Middle Aged; D009363:Neoplasm Proteins / Q000378:metabolism*; D010051:Ovarian Neoplasms / Q000378:metabolism / Q000503:physiopathology* / Q000601:surgery; D010053:Ovary / Q000378:metabolism / Q000601:surgery; D019894:Peptide YY / Q000378:metabolism*; D012720:Severity of Illness Index; D013330:Struma Ovarii / Q000378:metabolism / Q000503:physiopathology* / Q000601:surgery
chemical_list: D009363:Neoplasm Proteins; D019894:Peptide YY