title: Lambert-Eaton myasthenic syndrome following H1N1-influenza vaccination: a case report.
abstract: BACKGROUND
  The outbreak of influenza A (H1N1) pandemic during the year 2009 led to the development of several vaccinations against H1N1 virus. In Finland, 2.6 million citizens were vaccinated during pandemic 2009 - 2010 with adjuvanted influenza vaccine, Pandemrix(®) .
  
  
  METHODS
  In this case report, we describe a patient with non-paraneoplastic Lambert-Eaton myasthenic syndrome following Pandemrix(®)  vaccination.
  
  
  CONCLUSIONS
  Development of various autoimmune diseases in genetically predisposed subjects following exposure to certain environmental factors, including vaccinations, is a well-known entity. Clinicians should be aware of the possibility of the induction of autoimmune diseases following vaccinations and actively ask the relevant clinical history in a newly diagnosed patient with an autoimmune disorder.
authors.affiliation: Department of Neurology, Oulu University Hospital, Oulu, Finland. hanna.ansakorpi@ppshp.fi
authors.forename: Hanna
authors.initials: H
authors.lastname: Ansakorpi
authors.forename: Harri
authors.initials: H
authors.lastname: Rusanen
authors.forename: Seppo
authors.initials: S
authors.lastname: Rytky
authors.forename: Markus
authors.initials: M
authors.lastname: Färkkilä
mesh_terms: D000328:Adult; D001172:Arthritis, Rheumatoid / Q000150:complications; D001323:Autoantibodies / Q000097:blood / Q000276:immunology; D001324:Autoantigens / Q000276:immunology; D015220:Calcium Channels / Q000276:immunology; D005260:Female; D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype; D007252:Influenza Vaccines / Q000009:adverse effects*; D007251:Influenza, Human / Q000517:prevention & control; D015624:Lambert-Eaton Myasthenic Syndrome / Q000209:etiology* / Q000276:immunology* / Q000503:physiopathology*
chemical_list: D001323:Autoantibodies; D001324:Autoantigens; D015220:Calcium Channels; D007252:Influenza Vaccines; C556153:pandemrix