title: Solitary median maxillary central incisor: a report of 2 cases.
abstract: A single median maxillary central incisor (SMMCI) is a rare dental anomaly that may occur alone or be associated with growth deficiency or other systemic abnormalities. The best known association is with holoprosencephaly (HPE). HPE is a complex brain malformation that affects both  the forebrain and the face. Early diagnosis of SMMCI is important, since it may be a sign of other severe congenital or developmental abnormalities. Therefore, systematic follow-up and close monitoring of the growth and development of SMMCI patients is crucial. The purpose of this paper was  to report the cases of 2 children, each with a single median maxillary central incisor, and describe important symptoms of this syndrome that have not yet been reported.
authors.affiliation: Department of Oral and Maxillofacial Radiology, Faculty of Dentistry, Erciyes University, Kayseri, Turkey. aercansekerci@hotmail.com
authors.forename: Ahmet Ercan
authors.initials: AE
authors.lastname: Sekerci
authors.forename: Faruk Izzet
authors.initials: FI
authors.lastname: Uçar
authors.forename: Hüsniye
authors.initials: H
authors.lastname: Gümüş
authors.forename: Mustafa
authors.initials: M
authors.lastname: Aydınbelge
authors.forename: Yildiray
authors.initials: Y
authors.lastname: Sisman
mesh_terms: D000293:Adolescent; D005260:Female; D006801:Humans; D007180:Incisor; D008297:Male