title: Hemodynamic evaluation and anti-hypertensive schemes used in puerperal women following pre-eclampsia.
abstract: Pre-eclampsia is still a very prevalent disease with critical hemodynamic changes. This study was evaluated the major anti-hypertensive schemes used at the Materno Perinatal Hospital "Monica Pretelini" (HMPMP) hospitalized at the Obstetric Intensive Care Unit (OICU) for at least seven days. In other group of patients we compared hemodynamic monitoring with Swan-Ganz catheter versus transthoracic electrical bioimpedance (TEB) and gasometric formulas. Statistical analysis was done using the Statistical Package for Social Science (SPSS) software, version 17. Amlodipine + temisartan + prazocin was the preferred anti-hypertensive drug combination used in our intensive care unit. Sodium nitroprusside is required in 25% of patients until reaching control. There was no statistically significant difference in cardiac output calculated with gasometric formulas compared to thermodilution with Swan-Ganz catheter. Calcium antagonists + angiotensin II receptor blocker (ARB) + α-blockers offer the best option to control hypertension in puerperal women that followed pre-eclampsia, but oral and IV drugs to control hypertension is required in 20% of cases, in a Mexican Intensive Care Unit specialized in obstetrical patients. Hemodynamic monitoring with gasometric formulas is still usefull in this set of patients, without discarding TEB with a correction factor due to the accumulated extravascular water in these patients.
authors.affiliation: Autonomous University of the State of Mexico (UAEMex), Mexico.
authors.forename: G C
authors.initials: GC
authors.lastname: Rodriguez
authors.forename: H A
authors.initials: HA
authors.lastname: Albarran
authors.forename: H M
authors.initials: HM
authors.lastname: Zeron
mesh_terms: D000293:Adolescent; D000328:Adult; D017311:Amlodipine / Q000627:therapeutic use; D000959:Antihypertensive Agents / Q000627:therapeutic use*; D001562:Benzimidazoles / Q000627:therapeutic use; D001565:Benzoates / Q000627:therapeutic use; D001794:Blood Pressure; D002407:Catheterization, Swan-Ganz; D004359:Drug Therapy, Combination; D004461:Eclampsia / Q000188:drug therapy* / Q000503:physiopathology; D017097:Electric Impedance; D005260:Female; D005665:Furosemide / Q000627:therapeutic use; D006439:Hemodynamics; D006801:Humans; D009599:Nitroprusside / Q000627:therapeutic use; D049590:Postpartum Period; D011224:Prazosin / Q000627:therapeutic use; D011225:Pre-Eclampsia / Q000188:drug therapy* / Q000503:physiopathology; D011247:Pregnancy; D000077333:Telmisartan; D055815:Young Adult
chemical_list: D000959:Antihypertensive Agents; D001562:Benzimidazoles; D001565:Benzoates; D009599:Nitroprusside; D017311:Amlodipine; D005665:Furosemide; D000077333:Telmisartan; D011224:Prazosin