title: Improvement of pustulosis palmaris et plantaris by periodontal infection control in a patient with chronic periodontitis.
abstract: BACKGROUND
  Pustulosis palmaris et plantaris (PPP) is a chronic, inflammatory, autoimmune-type disease characterized by sterile pustules of skin. The skin inflammation is influenced by several factors such as drugs, sunlight, metabolic and psychogenic factors as well as metal allergy. Here, we report a rare case that intensive periodontal treatment might have contributed to the improvement of skin inflammation.
  
  
  RESULTS
  Skin inflammation regressed 1 month after intensive periodontal treatment. Both CD4/CD8 ratio and % of B cells in the blood sample were slightly decreased corresponding to the improvement of periodontal inflammation.
  
  
  CONCLUSIONS
  Infection control of periodontal lesions might be one of attractive therapeutic targets in management of PPP.
authors.affiliation: Division of Periodontics and Endodontics, Department of Conservative Dentistry and Oral Rehabilitation, Iwate Medical University, Morioka, Japan.
authors.forename: Osamu
authors.initials: O
authors.lastname: Murai
authors.forename: Daisuke
authors.initials: D
authors.lastname: Sasaki
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Ando
authors.forename: Akira
authors.initials: A
authors.lastname: Fujimura
authors.forename: Hiromi
authors.initials: H
authors.lastname: Oikawa
authors.forename: Nagisa
authors.initials: N
authors.lastname: Suwa
authors.forename: Daisuke
authors.initials: D
authors.lastname: Watabe
authors.forename: Fumihiko
authors.initials: F
authors.lastname: Maeda
authors.forename: Kohki
authors.initials: K
authors.lastname: Endo
authors.forename: Takashi
authors.initials: T
authors.lastname: Yaegashi
authors.forename: Toshihide
authors.initials: T
authors.lastname: Akasaka
authors.forename: Koji
authors.initials: K
authors.lastname: Naruishi
mesh_terms: D001402:B-Lymphocytes; D002097:C-Reactive Protein / Q000032:analysis; D016516:CD4-CD8 Ratio; D055113:Chronic Periodontitis / Q000150:complications* / Q000188:drug therapy*; D006801:Humans; D007958:Leukocyte Count; D008297:Male; D008875:Middle Aged; D011565:Psoriasis / Q000188:drug therapy* / Q000209:etiology* / Q000473:pathology; D012867:Skin / Q000473:pathology
chemical_list: D002097:C-Reactive Protein