title: [Cytomegalovirus ileitis in a non-immunocompromised old patient: a case report].
abstract: BACKGROUND
  Cytomegalovirus ileitis occurs rarely in immunocompetent subjects.
  
  
  METHODS
  An 88-year-old woman presented with severe pain located in right iliac fossa. Biological tests showed an increase in C-reactive protein and neutrophils. Colonoscopy revealed a severely ulcerated and inflamed terminal ileal mucosa. Histopathological analysis of biopsies showed a typical cytopathic effect with ballooned cells and intranuclear inclusions, confirmed by positive immunological marking with anti-cytomegalovirus antibodies. Cytomegalovirus polymerase chain reaction in the plasma showed positive activity. The patient was successfully treated with valganciclovir.
  
  
  CONCLUSIONS
  The predominant or isolated ileal location of cytomegalovirus infection should be known, especially in the elderly because aging could be a risk factor.
authors.affiliation: Service de médecine interne gériatrie, hôpital de Jour, hôpital de Champmaillot, CHU de Dijon, 2 rue Jules-Violle, Dijon cedex, France.
authors.forename: S
authors.initials: S
authors.lastname: Perrin
authors.forename: A
authors.initials: A
authors.lastname: Putot
authors.forename: H
authors.initials: H
authors.lastname: Guépet-Sordet
authors.forename: S
authors.initials: S
authors.lastname: Da Silva
authors.forename: S
authors.initials: S
authors.lastname: Somana
authors.forename: P
authors.initials: P
authors.lastname: Manckoundia
mesh_terms: D000369:Aged, 80 and over; D000998:Antiviral Agents / Q000627:therapeutic use; D003586:Cytomegalovirus Infections / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D005260:Female; D015774:Ganciclovir / Q000031:analogs & derivatives / Q000627:therapeutic use; D006801:Humans; D007079:Ileitis / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D007121:Immunocompetence / Q000502:physiology; D000077562:Valganciclovir
chemical_list: D000998:Antiviral Agents; D000077562:Valganciclovir; D015774:Ganciclovir