title: Pharmacological investigations on aglaia roxburghiana (w. &.a) miq. Var. Beddomei leaves.
abstract: Aglaia roxburghiana is a traditional remedy for a variety of diseases. The ethanolic extract of the leaves was screened for related activities were upon it exhibited significant anti-inflammatory activity in rats in acute and chronic models. There was no acute toxicity in mice upto 2g/kg. The extract protected the mast cell deregulation by compound 48/80 and inhibited histamine induced contractions in guinea pig ileum. The data obtained in this study suggest that the extract ma act by stabilizing mast cells ad blocking histamine receptors.
authors.affiliation: Department of pharmacology, sri ramachandra medical college & research institute, (Deemed University), Porur, Chennai - 600 116, Tamil Nadu, India.
authors.forename: S
authors.initials: S
authors.lastname: Janaki
authors.forename: S
authors.initials: S
authors.lastname: Vijayasekaran
authors.forename: R B
authors.initials: RB
authors.lastname: Rao