title: Synthesis, characterization and biological evaluation of Fe (III), Co (II), Ni(II), Cu(II), and Zn(II) complexes with tetradentate Schiff base ligand derived from protocatechualdehyde with 2-aminophenol.
abstract: Schiff base ligand (H(3)L) was prepared from the condensation reaction of protochatechualdehyde (3,4-dihydroxybenzaldhyde)with 2-amino phenol. From the direct reaction of the ligand (H(3)L) with Co(II), Ni(II) and Cu(II) chlorides, and Fe(III)and Zn(II)nitrates in 2 M/1 L molar ratio, the five new neutral complexes were prepared. The characterization of the newly formed compounds was done by (1)H NMR, UV-Vis, and IR spectroscopy and elemental analysis. The in vitro antibacterial activity of the metal complexes was studied and compared with that of free ligand.
authors.affiliation: Chemistry Department, Faculty of Science (boys), Al-Azhar University, Nasr City, Cairo, Egypt.
authors.forename: A M
authors.initials: AM
authors.lastname: Hassan
authors.forename: A M
authors.initials: AM
authors.lastname: Nassar
authors.forename: Y Z
authors.initials: YZ
authors.lastname: Hussien
authors.forename: A N
authors.initials: AN
authors.lastname: Elkmash
mesh_terms: D000627:Aminophenols / Q000737:chemistry*; D001547:Benzaldehydes / Q000737:chemistry*; D002396:Catechols / Q000737:chemistry*; D060326:Chemistry Techniques, Synthetic; D003035:Cobalt / Q000737:chemistry; D003300:Copper / Q000737:chemistry; D007501:Iron / Q000737:chemistry; D008024:Ligands; D019216:Metals, Heavy / Q000737:chemistry*; D009532:Nickel / Q000737:chemistry; D009942:Organometallic Compounds / Q000138:chemical synthesis* / Q000737:chemistry*; D012545:Schiff Bases / Q000737:chemistry; D013057:Spectrum Analysis; D013696:Temperature; D015032:Zinc / Q000737:chemistry
chemical_list: D000627:Aminophenols; D001547:Benzaldehydes; D002396:Catechols; D008024:Ligands; D019216:Metals, Heavy; D009942:Organometallic Compounds; D012545:Schiff Bases; C027667:2-aminophenol; D003035:Cobalt; C005581:protocatechualdehyde; D003300:Copper; D009532:Nickel; D007501:Iron; D015032:Zinc