title: Intractable chronic vulval ulceration presenting as immune reconstitution inflammatory syndrome in a treatment-failure patient: a case observation.
abstract: HIV-1 treatment-failure patients are increasingly being initiated on second-line antiretroviral therapy. The case we describe is of a treatment-failure patient who developed intractable chronic vulval ulceration presenting as immune reconstitution inflammatory syndrome (IRIS), following complete viral suppression with second-line highly active antiretroviral treatment (HAART). To the best of our knowledge, this is the first reported case of intractable vulval ulceration IRIS in an HIV-1 treatment-failure patient.
authors.affiliation: Department of Prevention, Care and Treatment, Infectious Diseases Institute, Makerere University College of Health Sciences, Kampala, Uganda.
authors.forename: Christine
authors.initials: C
authors.lastname: Katusiime
authors.forename: Ponsiano
authors.initials: P
authors.lastname: Ocama
authors.forename: Andrew
authors.initials: A
authors.lastname: Kambugu