title: Resveratrol and health: the starting point.
abstract: Cascade of youth? Resveratrol, the celebrated phytoalexin of red wine, was known to activate AMPK indirectly, but how this happened was unclear. In a paper recently published in Cell, S.-J. Park, J. H. Chung and co-workers identify the signalling cascade, which begins with the inhibition of phosphodiesterases, in particular PDE4. But questions remain, even while new perspectives open up.
authors.affiliation: CNR Institute of Neuroscience and Department of Biomedical Sciences, University of Padova, Viale Giuseppe Colombo 3, 35131 Padova, Italy.
authors.forename: Lucia
authors.initials: L
authors.lastname: Biasutto
authors.forename: Andrea
authors.initials: A
authors.lastname: Mattarei
authors.forename: Mario
authors.initials: M
authors.lastname: Zoratti
mesh_terms: D006262:Health; D006801:Humans; D008659:Metabolic Diseases / Q000188:drug therapy / Q000378:metabolism / Q000473:pathology; D000077185:Resveratrol; D015398:Signal Transduction / Q000187:drug effects; D013267:Stilbenes / Q000494:pharmacology* / Q000627:therapeutic use
chemical_list: D013267:Stilbenes; D000077185:Resveratrol