title: Effects of a standardized anesthetic protocol on hematologic variables in healthy cats.
abstract: This study evaluated the effects of an anesthetic protocol using intravenous ketamine and midazolam, and intramuscular buprenorphine on hematologic variables in cats. Twelve healthy adult cats had blood collected for a complete blood count before and after the induction of anesthesia. There were significant decreases in red blood cell counts, hemoglobin concentrations and hematocrits after the induction of anesthesia. On average, red blood cell counts and hematocrits decreased by 25%, and hemoglobin concentrations decreased by 24%. Based on hematocrit, 3/12 samples (25%) taken while the cats were anesthetized would have been interpreted as belonging to anemic patients while none of the cats would have been considered anemic before anesthesia. This study suggests that a complete blood count performed on blood taken under anesthesia with this anesthetic protocol should be interpreted cautiously in order to not make a false diagnosis of anemia.
authors.affiliation: Department of Small Animal Clinical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Canada. marc.dhumeaux@hotmail.fr
authors.forename: Marc P
authors.initials: MP
authors.lastname: Dhumeaux
authors.forename: Elisabeth C R
authors.initials: EC
authors.lastname: Snead
authors.forename: Tasha Y
authors.initials: TY
authors.lastname: Epp
authors.forename: Susan M
authors.initials: SM
authors.lastname: Taylor
authors.forename: Anthony P
authors.initials: AP
authors.lastname: Carr
authors.forename: Ryan M
authors.initials: RM
authors.lastname: Dickinson
authors.forename: Marina L
authors.initials: ML
authors.lastname: Leis
mesh_terms: D000768:Anesthesia, General / Q000662:veterinary*; D000771:Anesthesia, Intravenous / Q000662:veterinary*; D019162:Anesthetics, Combined / Q000008:administration & dosage*; D018686:Anesthetics, Intravenous / Q000008:administration & dosage*; D000818:Animals; D002047:Buprenorphine / Q000008:administration & dosage; D002415:Cats / Q000502:physiology*; D006400:Hematocrit / Q000662:veterinary*; D006439:Hemodynamics / Q000187:drug effects; D007649:Ketamine / Q000008:administration & dosage; D008874:Midazolam / Q000008:administration & dosage; D012016:Reference Values
chemical_list: D019162:Anesthetics, Combined; D018686:Anesthetics, Intravenous; D002047:Buprenorphine; D007649:Ketamine; D008874:Midazolam