title: Effects of a multicomponent wellness intervention on dyslipidemia among overweight adolescents.
abstract: Behavioral changes are the first line of treatment for dyslipidemia in adolescents, but outcome data on the effectiveness of this approach are inconsistent. This study aims to assess the effect of a 13-week multicomponent wellness intervention program, which included weekly nutrition classes and structured cardiovascular, flexibility, and strength training on dyslipidemia in nine overweight/obese [body mass index (BMI) > or = 85th percentile] and nine lean (BMI <85th percentile) adolescents. Clinical measurements and lipid profile assessment were performed before and after the intervention. At the completion of the study, the overweight/obese adolescents demonstrated a 15% increase in high-density lipoprotein cholesterol (HDL-C) levels (mean, 47 +/- 8 vs. 54 +/- 5 mg/dL), whereas there was no improvement in BMI or other measurements. The participants in the lean group showed no change in their anthropometric and serum parameters. A multicomponent wellness intervention resulted in a significant increase of cardioprotective HDL-C levels, which have been associated with coronary health in adulthood.
authors.affiliation: Department of Pediatrics, University of Massachusetts Medical School, Worcester, MA 01605, USA. hardyo@ummhc.org
authors.forename: Olga T
authors.initials: OT
authors.lastname: Hardy
authors.forename: Jean
authors.initials: J
authors.lastname: Wiecha
authors.forename: Albert
authors.initials: A
authors.lastname: Kim
authors.forename: Carlos
authors.initials: C
authors.lastname: Salas
authors.forename: Rayna
authors.initials: R
authors.lastname: Briceno
authors.forename: Kwesi
authors.initials: K
authors.lastname: Moody
authors.forename: Joan
authors.initials: J
authors.lastname: Becker
authors.forename: Greer
authors.initials: G
authors.lastname: Glazer
authors.forename: Carol
authors.initials: C
authors.lastname: Ciccarelli
authors.forename: Ling
authors.initials: L
authors.lastname: Shi
authors.forename: Laura L
authors.initials: LL
authors.lastname: Hayman
mesh_terms: D000293:Adolescent; D015992:Body Mass Index; D008076:Cholesterol, HDL / Q000097:blood*; D050171:Dyslipidemias / Q000097:blood*; D015444:Exercise; D005260:Female; D006801:Humans; D008297:Male; D009747:Nutritional Physiological Phenomena; D050177:Overweight / Q000097:blood*; D010353:Patient Education as Topic
chemical_list: D008076:Cholesterol, HDL