title: High-power diode laser versus electrocautery surgery on human papillomavirus lesion treatment.
abstract: The use of high-power lasers has facilitated and improved human papillomavirus (HPV) treatment protocols and has also become very popular in recent years. This application has been more frequently used in hospitals, especially in gynecology. The present study aimed to evaluate the effects of high-power diode laser to remove oral lesions caused by HPV and the consequent effects on virus load following the wound tissue healing process compared with one of the most conventional surgical techniques involving electrocautery. Surgeries were performed on 5 patients who had 2 distinct lesions caused by HPV. All patients were submitted to both electrocautery and high-power diode laser. Following a 20-day period, when the area was healed, sample material was collected through curettage for virus load quantitative analysis.Observation verified the presence of virus in all the samples; however, surgeries performed with the laser also revealed a significant reduction in virus load per cell compared with those performed with electrocautery. The ease when handling the diode laser, because of the flexibility of its fibers and precision of its energy delivery system, provides high-accuracy surgery, which facilitates the treatment of large and/or multifocal lesions. The use of high-power diode laser is more effective in treatment protocols of lesions caused by HPV.
authors.affiliation: Rehabilitation Center Lar Escola São Francisco, Centro de Reabilitação, São Paulo, Brazil.
authors.forename: Fernando Martins
authors.initials: FM
authors.lastname: Baeder
authors.forename: Maria Teresa Botti R
authors.initials: MT
authors.lastname: Santos
authors.forename: Jose Eduardo Pelizon
authors.initials: JE
authors.lastname: Pelino
authors.forename: Danilo Antonio
authors.initials: DA
authors.lastname: Duarte
authors.forename: Walter Joao
authors.initials: WJ
authors.lastname: Genovese
mesh_terms: D000328:Adult; D004564:Electrocoagulation; D005260:Female; D006801:Humans; D053685:Laser Therapy / Q000295:instrumentation / Q000379:methods*; D054023:Lasers, Semiconductor / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D009059:Mouth Diseases / Q000601:surgery* / Q000821:virology*; D030361:Papillomavirus Infections / Q000601:surgery*; D016133:Polymerase Chain Reaction; D018709:Statistics, Nonparametric; D016896:Treatment Outcome; D019562:Viral Load; D014945:Wound Healing