title: Nasal vestibulitis due to Nocardiopsis dassonvillei in a diabetic patient.
abstract: Human infection due to Nocardiopsis, an actinomycete, is rare and the majority of those infections are due to Nocardiopsis dassonvillei. This agent has been implicated in cutaneous, pulmonary, eye and disseminated infections. It has never been isolated from the nose or any nasal infection. We report here a rare case of nasal vestibular abscess due to N. dassonvillei in an adult diabetic patient. The bacterium was identified on the basis of morphological and biochemical characteristics, and confirmed by sequencing the 16S rRNA and hsp65 genes. The patient was successfully treated with clarithromycin and levofloxacin. Though N. dassonvillei infections may be rare, the study highlights that it may cause a wide spectrum of disease manifestations, and laboratories should take care to isolate and identify the easily treatable pathogen.
authors.affiliation: Mycology Division, Department of Medical Microbiology, Postgraduate Institute of Medical Education & Research (PGIMER), Chandigarh, India.
authors.forename: M Rudramurthy
authors.initials: MR
authors.lastname: Shivaprakash
authors.affiliation: Department of Microbiology, Mandya Institute of Medical Sciences (MIMS), Mandya, Karnataka, India.
authors.forename: B
authors.initials: B
authors.lastname: Sumangala
authors.affiliation: Mycology Division, Department of Medical Microbiology, Postgraduate Institute of Medical Education & Research (PGIMER), Chandigarh, India.
authors.forename: Honnavar
authors.initials: H
authors.lastname: Prasanna
authors.affiliation: Department of Microbiology, Mandya Institute of Medical Sciences (MIMS), Mandya, Karnataka, India.
authors.forename: Bindu Madhav
authors.initials: BM
authors.lastname: Yenigalla
authors.affiliation: Department of Microbiology, Mandya Institute of Medical Sciences (MIMS), Mandya, Karnataka, India.
authors.forename: K C
authors.initials: KC
authors.lastname: Munegowda
authors.affiliation: Department of ENT, Mandya Institute of Medical Sciences (MIMS), Mandya, Karnataka, India.
authors.forename: D
authors.initials: D
authors.lastname: Ravi
authors.affiliation: Mycology Division, Department of Medical Microbiology, Postgraduate Institute of Medical Education & Research (PGIMER), Chandigarh, India.
authors.forename: Arunaloke
authors.initials: A
authors.lastname: Chakrabarti
mesh_terms: D000038:Abscess / Q000175:diagnosis* / Q000382:microbiology / Q000473:pathology; D000192:Actinomycetales / Q000235:genetics / Q000302:isolation & purification*; D000193:Actinomycetales Infections / Q000175:diagnosis* / Q000382:microbiology / Q000473:pathology; D015373:Bacterial Typing Techniques; D016000:Cluster Analysis; D004269:DNA, Bacterial / Q000737:chemistry / Q000235:genetics; D048909:Diabetes Complications / Q000175:diagnosis* / Q000382:microbiology / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D008969:Molecular Sequence Data; D009666:Nose / Q000382:microbiology / Q000473:pathology*; D010802:Phylogeny; D017422:Sequence Analysis, DNA
chemical_list: D004269:DNA, Bacterial