title: A new model of a self-expanding tracheal stent made in Brazil: an experimental study in rabbits.
abstract: We aimed to test a new model of self-expanding tracheal stent so that it might be made available for clinical use. Using direct laryngoscopy, we placed polyurethane-coated, nitinol stents into the middle third of the trachea in 25 New Zealand rabbits. After a mean observation period of 26 days, we evaluated stent migration, degree of expansion, attachment, adherence, formation of granulation tissue, presence of inflammatory infiltrate, parietal involvement, and epithelial lining. The results showed complete radial expansion, little adherence to the tracheal mucosa, and low tissue attachment, as well as high rates of granuloma formation and stent migration. This new model proved to be biocompatible and showed a behavior similar to that of other stents on the market.
authors.affiliation: São José do Rio Preto School of Medicine, São José do Rio Preto, Rua Alcides Rossani 853, Vilage LaMontagne, São José do Rio Preto, SP, Brazil. fariamurilo@hotmail.com
authors.forename: Celso Murilo Nálio Matias de
authors.initials: CM
authors.lastname: Faria
authors.forename: Olavo Ribeiro
authors.initials: OR
authors.lastname: Rodrigues
authors.forename: Helio
authors.initials: H
authors.lastname: Minamoto
authors.forename: Patricia Maluf
authors.initials: PM
authors.lastname: Cury
authors.forename: José de Mendonça
authors.initials: Jde M
authors.lastname: Costa Neto
authors.forename: Domingo Marcolino
authors.initials: DM
authors.lastname: Braile
mesh_terms: D000497:Alloys; D000818:Animals; D001938:Brazil; D020099:Coated Materials, Biocompatible / Q000627:therapeutic use*; D011140:Polyurethanes; D011474:Prosthesis Design; D011817:Rabbits; D015607:Stents / Q000009:adverse effects; D014135:Tracheal Stenosis / Q000601:surgery*
chemical_list: D000497:Alloys; D020099:Coated Materials, Biocompatible; D011140:Polyurethanes; C013616:nitinol