title: Impact of a modified carbonated beverage on human dental plaque and salivary pH: an in vivo study.
abstract: BACKGROUND
  To assess the plaque and salivary pH changes at different time intervals in vivo after consumption of a carbonated beverage modified with sodium fluoride and calcium phosphate.
  
  
  METHODS
  Twenty-four subjects aged 18-25 years were recruited and randomly assigned to three groups (group A, original drink Sprite; group B, Sprite with sodium fluoride; group C, Sprite with calcium phosphate). Collection of pooled plaque and unstimulated saliva was done before and after the drinks were consumed by the subjects at 5-, 10-, 20- and 30-minute intervals.
  
  
  RESULTS
  The pH rise was higher with group C for plaque and group B for saliva.
  
  
  CONCLUSIONS
  Modification of the test carbonated beverage with calcium phosphate and fluoride may exert some protective potential, especially in high caries risk candidates.
authors.affiliation: Public Health Dentistry, Teerthanker Mahaveer Dental College and Research Center, Moradabad, Uttar Pradesh, India.
authors.forename: V
authors.initials: V
authors.lastname: Sardana
authors.forename: A Y
authors.initials: AY
authors.lastname: Balappanavar
authors.forename: G B
authors.initials: GB
authors.lastname: Patil
authors.forename: N
authors.initials: N
authors.lastname: Kulkarni
authors.forename: S G
authors.initials: SG
authors.lastname: Sagari
authors.forename: K D
authors.initials: KD
authors.lastname: Gupta
mesh_terms: D000293:Adolescent; D000328:Adult; D002130:Calcium Phosphates / Q000008:administration & dosage* / Q000032:analysis; D002253:Carbonated Beverages / Q000032:analysis; D003258:Consumer Behavior; D004245:DMF Index; D003773:Dental Plaque / Q000503:physiopathology*; D004311:Double-Blind Method; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008297:Male; D012463:Saliva / Q000187:drug effects*; D012969:Sodium Fluoride / Q000008:administration & dosage* / Q000032:analysis; D013649:Taste / Q000502:physiology; D055815:Young Adult
chemical_list: D002130:Calcium Phosphates; D012969:Sodium Fluoride; C020243:calcium phosphate