title: Facially-selective thymine-thymine photodimerization in TTT triads.
abstract: Irradiation of alkane-linked DNA hairpins possessing TTT steps with flanking purine bases yields products identified as the cis-syn (2 + 2) dimers formed between the central thymine and its 3'- and 5'-neighbors. Selective formation of the 3'-dimer is attributed to ground state conformational effects and electron transfer quenching by purine bases.
authors.affiliation: Department of Chemistry, Northwestern University, Evanston, Illinois 60208-3113, USA.
authors.forename: Prakash P
authors.initials: PP
authors.lastname: Neelakandan
authors.forename: Zhengzheng
authors.initials: Z
authors.lastname: Pan
authors.forename: Mahesh
authors.initials: M
authors.lastname: Hariharan
authors.forename: Frederick D
authors.initials: FD
authors.lastname: Lewis
mesh_terms: D004247:DNA / Q000737:chemistry / Q000528:radiation effects; D004579:Electron Transport; D055029:Inverted Repeat Sequences; D007536:Isomerism; D011740:Pyrimidine Dimers / Q000737:chemistry*; D011789:Quantum Theory; D013941:Thymine / Q000737:chemistry*; D014466:Ultraviolet Rays
chemical_list: D011740:Pyrimidine Dimers; D004247:DNA; D013941:Thymine