title: Multiple cavitary pulmonary nodules in association with pyoderma gangrenosum: case report.
abstract: Pyoderma gangrenosum is a rare neutrophilic disease of unknown origin that is associated with systemic diseases in 50% of cases. It is characterized by erythematous-violaceous nodular lesions that quickly progress to painful ulcers, with undermined edges, necrotic-hemorrhagic, varying in size and depth, located mainly in the lower limbs. Extracutaneous locations of pyoderma gangrenosum are rare, usually involving the lungs; the main differential diagnosis in these cases is Wegener granulomatosis. We report a case of pyoderma gangrenosum, which showed multiple cavitary lung nodules, with good response to high doses of steroids. Once excluded the possibility of Wegener granulomatosis, the authors concluded that it was the manifestation of systemic pyoderma gangrenosum with pulmonary involvement.
authors.affiliation: Fundação Santa Casa de Misericórdia do Pará, Belém, PA, Brazil. marayabittencourt@hotmail.com
authors.forename: Maraya de Jesus Semblano
authors.initials: Mde J
authors.lastname: Bittencourt
authors.forename: Luciana Fontenele Brito
authors.initials: LF
authors.lastname: Soares
authors.forename: Lilia Sampaio
authors.initials: LS
authors.lastname: Lobato
authors.forename: Alexandre Dias
authors.initials: AD
authors.lastname: Mançano
authors.forename: Helandro Stuart Castro
authors.initials: HS
authors.lastname: Leandro
authors.forename: Diana Mendes da
authors.initials: DM
authors.lastname: Fonseca
mesh_terms: D000293:Adolescent; D003937:Diagnosis, Differential; D014890:Granulomatosis with Polyangiitis / Q000175:diagnosis*; D006801:Humans; D008297:Male; D055613:Multiple Pulmonary Nodules / Q000175:diagnosis* / Q000209:etiology; D017511:Pyoderma Gangrenosum / Q000150:complications / Q000175:diagnosis*