title: Analysis of changes in crystalline lens thickness and its refractive power after laser in situ keratomileusis.
abstract: OBJECTIVE
  To evaluate changes in the anterior chamber depth (ACD), crystalline lens thickness (LT) and its refractive power after laser in situ keratomileusis (LASIK).
  
  
  METHODS
  In all cases, the preoperative and postoperative central ACD which were measured with Pentacam, Orbscan, IOL-Master and A-scan ultrasonography, central corneal true net power which was measured with the Pentacam, Orbscan and IOL-Master, axial length (AL) which was measured with IOL-Master and LT which was measured with the A-scan ultrasonography were compared using the paired sample t test. Ocular refractive errors and lens refractive power at corneal plane were calculated and their correlations were also evaluated before and after LASIK.
  
  
  RESULTS
  At 1 week after LASIK, LT and crystalline lens refractive power at corneal plane (Dlens) which were associated with the IOL-Master and Pentacam increased significantly (P≤0.005), ACD decreased significantly (P≤0.001), but no significant increase was observed in the Dlens which was associated with the Orbscan (P=0.261). Significant correlations between the changes in the ocular refractive errors and Dlens which were associated with the Pentacam were observed at 1 week and 6 months after LASIK (P=0.028; P=0.001).
  
  
  CONCLUSIONS
  LT increased significantly after LASIK, and this might partially lead to ACD decrease, Dlens increase and a small quantity of myopic regression.
authors.affiliation: Department of Ophthalmology, Guangdong General Hospital Affiliated to Southern Medical University, Guangzhou 510515, Guangdong Province, China.
authors.forename: Liang
authors.initials: L
authors.lastname: Wang
authors.forename: Hai-Ke
authors.initials: HK
authors.lastname: Guo
authors.forename: Jing
authors.initials: J
authors.lastname: Zeng
authors.forename: Hai-Ying
authors.initials: HY
authors.lastname: Jin