title: [A case of disseminated carcinomatosis of bone marrow treated by S-1 and cisplatin after distal gastrectomy for early gastric cancer].
abstract: Patients with bone metastasis originating from gastric cancer experience complications from DIC. They are treated with anticoagulation therapy or platelet transfusion, but their prognosis is poor. Our case was a 50-year-old male who had undergone distal gastrectomy for early gastric cancer[pT1a(M)N0M0, pStage I a]ten years previously. He was admitted to our hospital complaining of backache. As a result of his examination, he was diagnosed with disseminated carcinosis of bone marrow with DIC as a postoperative recurrence of gastric cancer. The patient was treated with combination chemotherapy of S-1 and cisplatin(S-1 80 mg/body, po, day 1-21 and cisplatin 50mg/body, iv, day 8). After one course of treatment, DIC was resolved and his pain was relieved. He survived for about nine months. S-1 and cisplatin are considered to be effective for disseminated carcinosis of bone marrow.
authors.affiliation: Department of Gastroenterology, Ishikawa Prefectural Central Hospital.
authors.forename: Kunihiro
authors.initials: K
authors.lastname: Tsuji
authors.forename: Hisashi
authors.initials: H
authors.lastname: Doyama
authors.forename: Shinya
authors.initials: S
authors.lastname: Yamada
authors.forename: Yoshifumi
authors.initials: Y
authors.lastname: Kaneko
authors.forename: Kenichi
authors.initials: K
authors.lastname: Takemura
authors.forename: Shigetsugu
authors.initials: S
authors.lastname: Tsuji
authors.forename: Kei
authors.initials: K
authors.lastname: Tominaga
authors.forename: Satoko
authors.initials: S
authors.lastname: Inagaki
authors.forename: Tomoyuki
authors.initials: T
authors.lastname: Hayashi
authors.forename: Renma
authors.initials: R
authors.lastname: Ito
authors.forename: Hiroyoshi
authors.initials: H
authors.lastname: Nakanishi
authors.forename: Yousuke
authors.initials: Y
authors.lastname: Kitou
authors.forename: Yasuhito
authors.initials: Y
authors.lastname: Takeda
authors.forename: Michihiro
authors.initials: M
authors.lastname: Yamamoto
authors.forename: Noriyuki
authors.initials: N
authors.lastname: Inaki
authors.forename: Tetsuji
authors.initials: T
authors.lastname: Yamada
authors.forename: Hideki
authors.initials: H
authors.lastname: Niwa
authors.forename: Kazuyoshi
authors.initials: K
authors.lastname: Katayanagi
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Kurumaya
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D019046:Bone Marrow Neoplasms / Q000150:complications / Q000188:drug therapy*; D002277:Carcinoma / Q000188:drug therapy* / Q000473:pathology; D002945:Cisplatin / Q000008:administration & dosage; D004211:Disseminated Intravascular Coagulation / Q000209:etiology; D004338:Drug Combinations; D017809:Fatal Outcome; D005743:Gastrectomy; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D010094:Oxonic Acid / Q000008:administration & dosage; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D005641:Tegafur / Q000008:administration & dosage
chemical_list: D004338:Drug Combinations; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid; D002945:Cisplatin