title: Mucoepidermoid carcinoma of the parotid gland in childhood survivor of acute lymphoblastic leukemia with need of radiotherapy for treatment and review of the literature.
abstract: Diagnosis of secondary malignancies began with the increasing survival in childhood cancer. Children treated for acute lymphoblastic leukemia (ALL) have an increased risk for developing mucoepidermoid carcinoma (MEC) of the parotid gland. The latent period ranges from 5 to 16 years. A 2 6/12-year-old girl was treated for pro-B ALL. Treatment included multidrug chemotherapy, prophylactic intrathecal methotrexate, and cranial radiotherapy. MEC of the left parotid gland was diagnosed at the age of 8 years, 3 years after completing treatment. She was treated with multiple surgery and radiotherapy. The authors aimed to emphasize the need for concern about second cancers of the parotid gland in children treated for ALL.
authors.forename: Deniz
authors.initials: D
authors.lastname: Tugcu
authors.forename: Ferhan
authors.initials: F
authors.lastname: Akici
authors.forename: Gonul
authors.initials: G
authors.lastname: Aydogan
authors.forename: Zafer
authors.initials: Z
authors.lastname: Salcioglu
authors.forename: Arzu
authors.initials: A
authors.lastname: Akcay
authors.forename: Hulya
authors.initials: H
authors.lastname: Sen
authors.forename: Fulya Yaman
authors.initials: FY
authors.lastname: Agaoglu
authors.forename: Emin
authors.initials: E
authors.lastname: Darendeliler
authors.forename: Yasemin
authors.initials: Y
authors.lastname: Ozluk
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage; D018277:Carcinoma, Mucoepidermoid / Q000532:radiotherapy*; D002648:Child; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D016609:Neoplasms, Second Primary / Q000532:radiotherapy*; D010307:Parotid Neoplasms / Q000532:radiotherapy*; D015452:Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / Q000628:therapy*; D017741:Survivors