title: Autochthonous disseminated dermal and visceral leishmaniasis in an AIDS patient, southern Thailand, caused by Leishmania siamensis.
abstract: We report the first establishment of in vitro cultivation and genotypic characterization of Leishmania siamensis isolated from an autochthonous disseminated dermal and visceral leishmaniasis in a Thai acquired immunodeficiency syndrome (AIDS) patient. The molecular identification has shown that the parasite was identical to L. siamensis, a recently described Leishmania species reported in the southern provinces of Thailand. The phylogenetic analysis has confirmed L. siamensis as closely related to the zoonotic Leishmania species L. enrietti.
authors.affiliation: Department of Dermatology, Trang Hospital, Trang, Thailand. dr_lertwut_clinic@yahoo.com
authors.forename: Lertwut
authors.initials: L
authors.lastname: Bualert
authors.forename: Wiwat
authors.initials: W
authors.lastname: Charungkiattikul
authors.forename: Paramee
authors.initials: P
authors.lastname: Thongsuksai
authors.forename: Mathirut
authors.initials: M
authors.lastname: Mungthin
authors.forename: Suradej
authors.initials: S
authors.lastname: Siripattanapipong
authors.forename: Rommanee
authors.initials: R
authors.lastname: Khositnithikul
authors.forename: Tawee
authors.initials: T
authors.lastname: Naaglor
authors.forename: Christophe
authors.initials: C
authors.lastname: Ravel
authors.forename: Fouad
authors.initials: F
authors.lastname: El Baidouri
authors.forename: Saovanee
authors.initials: S
authors.lastname: Leelayoova
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000150:complications / Q000188:drug therapy / Q000469:parasitology*; D000163:Acquired Immunodeficiency Syndrome / Q000150:complications / Q000188:drug therapy / Q000469:parasitology*; D000328:Adult; D019380:Anti-HIV Agents / Q000627:therapeutic use; D005260:Female; D017125:Genes, Protozoan; D006801:Humans; D019259:Lamivudine / Q000627:therapeutic use; D007891:Leishmania / Q000235:genetics* / Q000302:isolation & purification / Q000472:pathogenicity; D016773:Leishmaniasis, Cutaneous / Q000150:complications* / Q000188:drug therapy / Q000469:parasitology; D007898:Leishmaniasis, Visceral / Q000150:complications* / Q000188:drug therapy / Q000469:parasitology; D019829:Nevirapine / Q000627:therapeutic use; D010802:Phylogeny; D018119:Stavudine / Q000627:therapeutic use; D013785:Thailand / Q000453:epidemiology
chemical_list: D019380:Anti-HIV Agents; D019259:Lamivudine; D019829:Nevirapine; D018119:Stavudine