title: Ruthenium(II) complex-based fluorescent sensor for peroxynitrite.
abstract: We have developed a new ruthenium complex, Ru(bpy)(2)[4-(2,2'-bipyridin-4-yloxy)phenol]Cl(2) (RuL), as a fluorescent sensor to detect peroxynitrite (ONOO(-)). The results showed that the addition of ONOO(-) to the aqueous solution of RuL would result in distinct fluorescence quenching at 600nm. RuL exhibits a good selectivity for ONOO(-) over other reactive oxygen species (ROS) and reactive nitrite species (RNS), and the reaction time is less than 1.5s. The sensing mechanism is proposed as the oxidative O-dealkylation reaction.
authors.affiliation: Key Laboratory of Photochemical Conversion and Optoelectronic Materials, Technical Institute of Physics and Chemistry, The Chinese Academy of Sciences, Beijing 100190, PR China.
authors.forename: Jingjin
authors.initials: J
authors.lastname: Ma
authors.forename: Jiasheng
authors.initials: J
authors.lastname: Wu
authors.forename: Weimin
authors.initials: W
authors.lastname: Liu
authors.forename: Pengfei
authors.initials: P
authors.lastname: Wang
authors.forename: Zhiyuan
authors.initials: Z
authors.lastname: Fan
mesh_terms: D015374:Biosensing Techniques / Q000379:methods*; D056831:Coordination Complexes / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D030421:Peroxynitrous Acid / Q000737:chemistry*; D012428:Ruthenium / Q000737:chemistry*; D013050:Spectrometry, Fluorescence; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; D013056:Spectrophotometry, Ultraviolet; D013997:Time Factors
chemical_list: D056831:Coordination Complexes; D030421:Peroxynitrous Acid; D012428:Ruthenium