title: Solid-phase parallel synthesis of drug-like artificial 2H-benzopyran libraries.
abstract: This review covers the construction of drug-like 2H-benzopyrans and related libraries using solid-phase parallel synthesis. In this context, the preparation of substituted benzopyrans such as mono-, di- and trisubstituted benzopyran derivatives and additional ring-fused benzopyrans such as benzopyranoisoxazoles, benzopyranopyrazoles, six-membered ring-fused benzopyrans, and polycyclic benzopyrans are highlighted.
authors.affiliation: Research Institute of Pharmaceutical Sciences, College of Pharmacy, Kyungpook National University, Buk-gu, Daegu, Korea. tlee@knu.ac.kr
authors.forename: Taeho
authors.initials: T
authors.lastname: Lee
authors.forename: Young-Dae
authors.initials: YD
authors.lastname: Gong
mesh_terms: D001578:Benzopyrans / Q000138:chemical synthesis*; D020650:Combinatorial Chemistry Techniques; D055808:Drug Discovery; D015394:Molecular Structure; D004364:Pharmaceutical Preparations; D054852:Small Molecule Libraries / Q000138:chemical synthesis*; D060327:Solid-Phase Synthesis Techniques / Q000379:methods*
chemical_list: D001578:Benzopyrans; D004364:Pharmaceutical Preparations; D054852:Small Molecule Libraries