title: Why do some T cell receptor cytoplasmic domains associate with the plasma membrane?
abstract: Based on studies in model systems it has been proposed that the cytoplasmic domains of T cell receptor signaling subunits that have polybasic motifs associate with the plasma membrane, and that this regulates their phosphorylation. Recent experiments in more physiological systems have confirmed membrane association but raised questions as to its function.
authors.affiliation: Sir William Dunn School of Pathology, University of Oxford Oxford, UK.
authors.forename: P Anton
authors.initials: PA
authors.lastname: van der Merwe
authors.forename: Hao
authors.initials: H
authors.lastname: Zhang
authors.forename: Shaun-Paul
authors.initials: SP
authors.lastname: Cordoba