title: Relationship between sex hormone fluctuations and biomarkers of bone resorption in bovine plasma during the oestrous cycle.
abstract: The objective of this study was to determine the potential influence of fluctuations in the sex hormones progesterone and oestradiol-17β (E(2)), on biomarkers of bone resorption (hydroxyproline [HYP] and tartrate-resistant acid phosphatase isoform 5b [TRAP5b]) during the oestrous cycle of Holstein cows. Over the course of the study, plasma HYP concentrations did not change and alterations in the concentration of TRAP5b negatively correlated with E(2) levels: enhanced TRAP5b activity correlated with decreased E(2) concentrations below a defined level. This finding enhances the understanding of calcium homeostasis in post-partum dairy cows.
authors.affiliation: Department of Veterinary Medicine, Faculty of Agriculture, Iwate University, Morioka, Iwate 020-8550, Japan.
authors.forename: Bhuminand
authors.initials: B
authors.lastname: Devkota
authors.forename: Kouki
authors.initials: K
authors.lastname: Itagaki
authors.forename: Danil
authors.initials: D
authors.lastname: Kim
authors.forename: Kouya
authors.initials: K
authors.lastname: Sasaki
authors.forename: Takeshi
authors.initials: T
authors.lastname: Osawa
authors.forename: Kazuhisa
authors.initials: K
authors.lastname: Furuhama
authors.forename: Norio
authors.initials: N
authors.lastname: Yamagishi
mesh_terms: D000135:Acid Phosphatase / Q000097:blood; D000818:Animals; D015415:Biomarkers / Q000097:blood*; D001862:Bone Resorption / Q000097:blood / Q000662:veterinary*; D002118:Calcium / Q000378:metabolism; D002417:Cattle / Q000097:blood*; D004958:Estradiol / Q000097:blood; D030762:Estrous Cycle / Q000097:blood*; D005260:Female; D012739:Gonadal Steroid Hormones / Q000097:blood*; D006706:Homeostasis; D006909:Hydroxyproline / Q000097:blood; D007527:Isoenzymes / Q000097:blood; D011374:Progesterone / Q000097:blood; D000071681:Tartrate-Resistant Acid Phosphatase
chemical_list: D015415:Biomarkers; D012739:Gonadal Steroid Hormones; D007527:Isoenzymes; D011374:Progesterone; D004958:Estradiol; D000135:Acid Phosphatase; D000071681:Tartrate-Resistant Acid Phosphatase; D006909:Hydroxyproline; D002118:Calcium