title: Off-targeting oft-targeted CD20 in cHL.
abstract: We now think of classical Hodgkin lymphoma (cHL) as derived from "crippled" germinal center B cells that have frequently acquired rearranged and somatically mutated Ig genes.1,2 Despite their B-cell origin, the malignant Hodgkin and Reed-Sternberg (HRS) cells have lost most of the superficial trappings of B cells and therefore have been hidden from investigators' lenses for decades, prompting an arduous but persistent race to uncover the mystery of the HRS cell.
authors.affiliation: Robert H. Lurie Comprehensive Cancer Center.
authors.forename: Leo I
authors.initials: LI
authors.lastname: Gordon
authors.forename: Richard
authors.initials: R
authors.lastname: Longnecker