title: Purgative and anti-inflammatory activities of cassia didymobotrya, fresen.
abstract: Aqueous and ethanol extracts of cassia didymobotraya were investigated for purgative and anit-inflammatory activities in albino mice and rats, respectively at a dose of 100 mg/kg body weight. Anti-inflammatory activity was screened by 1% carageenan induced paw edema method and purgative activity was screened by the method described by Akah etal, Both the extracts exhibited significant purgative and anti-inflammatory activities, which are comparable to standard drugs, Senna (20mg/kg) and indomethacin (20mg/kg). Ethanol extract showed higher purgative and anti-inflammatory than aqueous extract. The percentage of protection of aqueous, ethanol extracts and indomethacin were found to be 35.29,37.25 and 43.13.
authors.affiliation: Department of Pharmacognosy, J.S.S College of Pharmacy, Ooty-643 001, The Nilgiris, Tamilnadu, India.
authors.forename: N
authors.initials: N
authors.lastname: Mahadevan
authors.forename: B G
authors.initials: BG
authors.lastname: Upendra
authors.forename: T
authors.initials: T
authors.lastname: Subburaju
authors.forename: K
authors.initials: K
authors.lastname: Elango
authors.forename: B
authors.initials: B
authors.lastname: Suresh