title: [Safety and effectiveness of testicular prosthesis implantation for testis loss: clinical observation of 18 cases].
abstract: OBJECTIVE
  To investigate the effect and safety of the implantation of a new type of testicular prosthesis in the treatment of testis loss.
  
  
  METHODS
  We recruited for this study 18 patients with testis loss treated by testicular prosthesis implantation, including 10 cases of prostate cancer, 3 cases of anorchia, 2 case of orchiatrophy, 2 cases of hermaphroditism and 1 case of cryptorchidism. The prosthesis was a hollow silicone elastomer YH-G1 made in China, selected according to the volume of the scrotum and the size of the contralateral testis.
  
  
  RESULTS
  Thirteen of the patients received testicular prosthesis implantation with orchiectomy, and the other 5 underwent the procedure 6 months later. The operation time of testicular prosthesis implantation was (22.6 +/- 4.6) min, ranging from 15 to 30 minutes. All the patients were discharged after 12 hours of postoperative observation, with a mean hospital stay of (1.3 +/- 0.4) days. A follow-up after 6 months revealed no complications in 17 cases. Rejection occurred in 1 case at 3 months after the implantation, ending in the removal of the prosthesis. Of the 17 successful cases, 15 were very satisfied with the size of the prosthesis, 14 with its weight, 12 with its comfortableness, and all with the appearance of the scrotum and the position of the prosthesis, while 5 found the implant too rigid.
  
  
  CONCLUSIONS
  The implantation of the new home-made silicone elastomer testicular prosthesis YH-G1 was safe and effective for the treatment of testis loss, and could meet the esthetic and psychological requirements of the patient. But further observation is needed for its long-term complications and influence on the patient's quality of life.
authors.affiliation: Department of Urology, Renji Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, 200001, China.
authors.forename: Hui-Xing
authors.initials: HX
authors.lastname: Chen
authors.forename: Ye
authors.initials: Y
authors.lastname: Ning
authors.forename: Zhi-Kang
authors.initials: ZK
authors.lastname: Cai
authors.forename: Ping
authors.initials: P
authors.lastname: Ping
authors.forename: Mei
authors.initials: M
authors.lastname: Huang
authors.forename: Di-Ping
authors.initials: DP
authors.lastname: Xu
authors.forename: Jun-Jie
authors.initials: JJ
authors.lastname: Bo
authors.forename: Yi-Ran
authors.initials: YR
authors.lastname: Huang
authors.forename: Zhong
authors.initials: Z
authors.lastname: Wang
authors.forename: Zheng
authors.initials: Z
authors.lastname: Li
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D006061:Gonadal Dysgenesis, 46,XY / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009919:Orchiectomy; D017060:Patient Satisfaction; D019736:Prostheses and Implants; D019919:Prosthesis Implantation / Q000009:adverse effects; D012826:Silicone Elastomers; D013737:Testis / Q000002:abnormalities / Q000601:surgery*; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D012826:Silicone Elastomers