title: Ruditapes decussatus and Ruditapes philippinarum exposed to cadmium: toxicological effects and bioaccumulation patterns.
abstract: Since differences in metal accumulation may exist between bivalve species, the aim of this study was to assess the impact of cadmium (Cd) on Ruditapes decussatus and Ruditapes philippinarum. For this, the Cd accumulation, mortality rates and biochemical responses were analysed in the two species after 5days of exposure, under laboratory-controlled conditions. The concentration of Cd that caused 50% of mortality on clams was two-times higher in R. decussatus than in R. philippinarum. For both species, higher percentage (84.5-98.2%) of the Cd was in the insoluble fraction, but the Cd concentration in solution was 3 to 8 times higher in R. decussatus. Nevertheless, R. philippinarum presented higher oxidative stress and higher CAT activity. The paradox observed between the two clams can be explained by the higher capacity of R. decussatus to increase the expression of MTs when exposed to Cd.
authors.affiliation: CBC, Departamento de Biologia, Universidade de Aveiro, Portugal. efigueira@ua.pt
authors.forename: Etelvina
authors.initials: E
authors.lastname: Figueira
authors.forename: Paulo
authors.initials: P
authors.lastname: Cardoso
authors.forename: Rosa
authors.initials: R
authors.lastname: Freitas
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000378:metabolism; D015415:Biomarkers / Q000378:metabolism; D049872:Bivalvia / Q000187:drug effects* / Q000378:metabolism; D002104:Cadmium / Q000493:pharmacokinetics / Q000633:toxicity*; D015500:Chloramphenicol O-Acetyltransferase / Q000378:metabolism*; D004789:Enzyme Activation; D015227:Lipid Peroxidation; D008668:Metallothionein / Q000378:metabolism; D018384:Oxidative Stress; D012995:Solubility; D013045:Species Specificity; D013482:Superoxide Dismutase / Q000378:metabolism; D014874:Water Pollutants, Chemical / Q000493:pharmacokinetics / Q000633:toxicity*
chemical_list: D000975:Antioxidants; D015415:Biomarkers; D014874:Water Pollutants, Chemical; D002104:Cadmium; D008668:Metallothionein; D013482:Superoxide Dismutase; D015500:Chloramphenicol O-Acetyltransferase