title: Pediatric vasculitis.
abstract: Childhood vasculitis is a challenging and complex group of conditions that are multisystem in nature and often require integrated care from multiple subspecialties, including rheumatology, dermatology, cardiology, nephrology, neurology, and gastroenterology. Vasculitis is defined as the presence of inflammation in the blood vessel wall. The site of vessel involvement, size of the affected vessels, extent of vascular injury, and underlying pathology determine the disease phenotype and severity. This article explores the classification and general features of pediatric vasculitis, as well as the clinical presentation, diagnostic evaluation, and therapeutic options for the most common vasculitides.
authors.affiliation: Division of Rheumatology and Center for Pediatric Clinical Effectiveness, Children's Hospital of Philadelphia, Colkett Translational Research Building, Philadelphia, PA 19104, USA. weisspa@email.chop.edu
authors.forename: Pamela F
authors.initials: PF
authors.lastname: Weiss
mesh_terms: D000700:Analgesics / Q000627:therapeutic use; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D002648:Child; D006801:Humans; D011695:IgA Vasculitis / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology / Q000628:therapy; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D007155:Immunologic Factors / Q000627:therapeutic use; D009080:Mucocutaneous Lymph Node Syndrome / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology / Q000209:etiology; D010956:Plasmapheresis; D010488:Polyarteritis Nodosa / Q000175:diagnosis / Q000188:drug therapy; D013625:Takayasu Arteritis / Q000175:diagnosis / Q000188:drug therapy; D014657:Vasculitis / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology / Q000628:therapy; D020293:Vasculitis, Central Nervous System / Q000175:diagnosis / Q000188:drug therapy
chemical_list: D000700:Analgesics; D000893:Anti-Inflammatory Agents; D016756:Immunoglobulins, Intravenous; D007155:Immunologic Factors