title: Antipyretic activity of Radix paeoniae.
abstract: The acetone extracts of Radix paeoniae (Paeonaceae) root (100 and 200 mg/kg orally) were tested in brewer's yeast-induced pyrexia in rats to assess their antipyretic activity. The pyrexia in rats was reduced significantly (P < 0.05) compared to that of control. These results indicate that the extracts possess antipyretic properties. The root extract showed significant reduction in normal body temperature and yeast-provoked elevated temperature comparable to that of standard antipyretic drug paracetamol. The antipyretic effect was started at 1h and extended for at least 4h after the drug administration.
authors.affiliation: B.R. Nahata College of Pharmacy, Mandsaur (M.P.), India.
authors.forename: Sapna
authors.initials: S
authors.lastname: Motwani
authors.forename: Neelesh
authors.initials: N
authors.lastname: Malviya
authors.forename: R K
authors.initials: RK
authors.lastname: Goel
authors.forename: K R
authors.initials: KR
authors.lastname: Dutt