title: Rare solid tumors of the pancreas as differential diagnosis of pancreatic adenocarcinoma.
abstract: BACKGROUND
  Rare solid tumors of the pancreas can be misinterpreted as primary pancreatic cancer.
  
  
  OBJECTIVE
  The aim of this study was to report our experience in the treatment of patients with rare tumor lesions of the pancreas and to discuss clinical and pathological characteristics in the context of the role of surgery.
  
  
  METHODS
  Data from patients of our prospective data-base with rare benign and malignant tumors of the pancreas, treated in our division from January 2004 to August 2010, were analyzed retrospectively.
  
  
  RESULTS
  One-thousand and ninety-eight patients with solid tumors of the pancreas underwent pancreatic surgery. In 19 patients (10 women, 9 men) with a mean age of 57 years (range: 20-74 years) rare pancreatic tumors (metastasis, solid pseudopapillary tumor, teratoma, hemangioma, accessory spleen, lymphoepithelial cyst, hamartoma, sarcoidosis, yolk sac tumor) were the reason for surgical intervention.
  
  
  CONCLUSIONS
  If rare benign and malignant pancreatic tumors, intrapancreatic metastasis, as well as pancreatic malformations or other abnormalities, present themselves as solid masses of the pancreas, they constitute an important differential diagnosis to primary pancreatic neoplasia, e.g. pancreatic ductal adenocarcinoma. Clinical imaging techniques cannot always rule out malignancy, thus operative exploration often remains the treatment of choice to provide the correct diagnosis and initiate adequate surgical therapy.
authors.affiliation: Department of General and Visceral Surgery, St. Josef-Hospital, Ruhr-University Bochum. Bochum, Germany.
authors.forename: Sabine
authors.initials: S
authors.lastname: Kersting
authors.forename: Monika S
authors.initials: MS
authors.lastname: Janot
authors.forename: Johanna
authors.initials: J
authors.lastname: Munding
authors.forename: Dominique
authors.initials: D
authors.lastname: Suelberg
authors.forename: Andrea
authors.initials: A
authors.lastname: Tannapfel
authors.forename: Ansgar M
authors.initials: AM
authors.lastname: Chromik
authors.forename: Waldemar
authors.initials: W
authors.lastname: Uhl
authors.forename: Uwe
authors.initials: U
authors.lastname: Bergmann
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis* / Q000473:pathology* / Q000601:surgery; D000328:Adult; D000368:Aged; D001706:Biopsy; D018267:Carcinoma, Acinar Cell / Q000175:diagnosis / Q000473:pathology; D021441:Carcinoma, Pancreatic Ductal / Q000175:diagnosis* / Q000473:pathology* / Q000601:surgery; D002291:Carcinoma, Papillary / Q000175:diagnosis / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D006222:Hamartoma / Q000175:diagnosis / Q000473:pathology; D006391:Hemangioma / Q000175:diagnosis / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010180:Pancreatectomy; D010190:Pancreatic Neoplasms / Q000175:diagnosis* / Q000473:pathology* / Q000601:surgery; D011446:Prospective Studies; D012189:Retrospective Studies