title: First report of spontaneous intrapartum Atopobium vaginae bacteremia.
abstract: We report the first case of spontaneous intrapartum Atopobium vaginae bacteremia identified by 16S rRNA gene sequencing. The bacterium was misidentified by RapID ANA II, API Rapid ID 32A, and matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS). The likely source of bacteremia was the female genital tract. In invasive infections caused by A. vaginae, β-lactams and clindamycin are the antibiotics of choice, as most strains are resistant to metronidazole.
authors.affiliation: Department of Microbiology, The University of Hong Kong, Queen Mary Hospital, Hong Kong.
authors.forename: Jasper F W
authors.initials: JF
authors.lastname: Chan
authors.forename: Susanna K P
authors.initials: SK
authors.lastname: Lau
authors.forename: Shirly O T
authors.initials: SO
authors.lastname: Curreem
authors.forename: Kelvin K W
authors.initials: KK
authors.lastname: To
authors.forename: Sally S M
authors.initials: SS
authors.lastname: Leung
authors.forename: Vincent C C
authors.initials: VC
authors.lastname: Cheng
authors.forename: Kwok-Yung
authors.initials: KY
authors.lastname: Yuen
authors.forename: Patrick C Y
authors.initials: PC
authors.lastname: Woo
mesh_terms: D039903:Actinobacteria / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D016470:Bacteremia / Q000175:diagnosis* / Q000382:microbiology / Q000473:pathology; D002981:Clindamycin / Q000627:therapeutic use; D004269:DNA, Bacterial / Q000737:chemistry / Q000235:genetics; D004275:DNA, Ribosomal / Q000737:chemistry / Q000235:genetics; D024881:Drug Resistance, Bacterial; D005260:Female; D016908:Gram-Positive Bacterial Infections / Q000175:diagnosis* / Q000382:microbiology / Q000473:pathology; D006801:Humans; D008969:Molecular Sequence Data; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis* / Q000382:microbiology / Q000473:pathology; D012336:RNA, Ribosomal, 16S / Q000235:genetics; D017422:Sequence Analysis, DNA; D047090:beta-Lactams / Q000627:therapeutic use
chemical_list: D000900:Anti-Bacterial Agents; D004269:DNA, Bacterial; D004275:DNA, Ribosomal; D012336:RNA, Ribosomal, 16S; D047090:beta-Lactams; D002981:Clindamycin