title: Pregnancy- and lactation-associated transient osteoporosis of both hips in a 32 year old patient with osteogenesis imperfecta.
abstract: Combination of osteogenesis imperfecta (OI), pregnancy, and transient osteoporosis (TO) of the hip is rare, only a few cases have been published so far. We report a 32 year old woman with OI, with TO on the right hip in her late third trimester. Non-pharmacological measures such as non-weight-bearing resulted in complete remission. Shortly after weaning, TO of the contralateral hip developed and non-pharmacological measures remained ineffective this time. Under treatment with a prostaglandin I(2) analog (iloprost), i.v. bisphosphonate (pamidronate), calcium and vitamin D supplementation rapid improvement of pain and complete remission was achieved.
authors.affiliation: Orthopädisch Physiotherapeutisches Zentrum Graz, Austria. pabinger@opz.at
authors.forename: C
authors.initials: C
authors.lastname: Pabinger
authors.forename: C
authors.initials: C
authors.lastname: Heu
authors.forename: A
authors.initials: A
authors.lastname: Frohner
authors.forename: H P
authors.initials: HP
authors.lastname: Dimai
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007774:Lactation / Q000502:physiology*; D010013:Osteogenesis Imperfecta / Q000378:metabolism / Q000503:physiopathology*; D010024:Osteoporosis / Q000378:metabolism / Q000503:physiopathology*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000378:metabolism / Q000503:physiopathology*