title: [A case study of advanced gastric cancer patient treated with S-1+paclitaxel/lentinan].
abstract: A 47 -year-old male presented with gastric cancer, with right cervical and para-aortic lymph node metastases. The patient had not undergone a curative operation, but was treated with immunochemotherapy in combination with S-1 60 mg/m2(2 weeks administration and 2 weeks rest), paclitaxel 60 mg/m²(day 1, 8, 15), and Lentinan 2mg/body(day 1, 8, 15). After 3 courses of this treatment, no hot-spots were identified on cervical and para-aorta lymph nodes by PET-CT examination. We decided to perform total gastrectomy with D3 lymphadenectomy and Roux-en Y reconstruction. On histopathological examination, no malignancy was seen in the lymph nodes and the main tumor was judged to be grade 2. With this combined immunochemotherapy, the patient had a favorable outcome without side effects, which proved effective for far advanced gastric cancer.
authors.affiliation: Department of Surgery, Kansai Medical University.
authors.forename: Koji
authors.initials: K
authors.lastname: Nakai
authors.forename: Masanori
authors.initials: M
authors.lastname: Yamada
authors.forename: Yosuke
authors.initials: Y
authors.lastname: Ueyama
authors.forename: Takashi
authors.initials: T
authors.lastname: Ozaki
authors.forename: Taku
authors.initials: T
authors.lastname: Michiura
authors.forename: Kentaro
authors.initials: K
authors.lastname: Inoue
authors.forename: Yusai
authors.initials: Y
authors.lastname: Kawaguchi
authors.forename: Hideho
authors.initials: H
authors.lastname: Takada
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Nakane
authors.forename: A-Hon
authors.initials: AH
authors.lastname: Kwon
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D004338:Drug Combinations; D005743:Gastrectomy; D006801:Humans; D007912:Lentinan / Q000008:administration & dosage; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D010094:Oxonic Acid / Q000008:administration & dosage; D017239:Paclitaxel / Q000008:administration & dosage; D012074:Remission Induction; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D005641:Tegafur / Q000008:administration & dosage
chemical_list: D004338:Drug Combinations; C079198:S 1 (combination); D005641:Tegafur; D007912:Lentinan; D010094:Oxonic Acid; D017239:Paclitaxel