title: Local signal time-series during rest used for areal boundary mapping in individual human brains.
abstract: It is widely thought that resting state functional connectivity likely reflects functional interaction among brain areas and that different functional areas interact with different sets of brain areas. A method for mapping areal boundaries has been formulated based on the large-scale spatial characteristics of regional interaction revealed by resting state functional connectivity. In the present study, we present a novel analysis for areal boundary mapping that requires only the signal timecourses within a region of interest, without reference to the information from outside the region. The areal boundaries were generated by the novel analysis and were compared with those generated by the previously-established standard analysis. The boundaries were robust and reproducible across the two analyses, in two regions of interest tested. These results suggest that the information for areal boundaries is readily available inside the region of interest.
authors.affiliation: Department of Physiology, The University of Tokyo School of Medicine, Bunkyo-ku, Tokyo, Japan. sahirose@m.u-tokyo.ac.jp
authors.forename: Satoshi
authors.initials: S
authors.lastname: Hirose
authors.forename: Takamitsu
authors.initials: T
authors.lastname: Watanabe
authors.forename: Koji
authors.initials: K
authors.lastname: Jimura
authors.forename: Masaki
authors.initials: M
authors.lastname: Katsura
authors.forename: Akira
authors.initials: A
authors.lastname: Kunimatsu
authors.forename: Osamu
authors.initials: O
authors.lastname: Abe
authors.forename: Kuni
authors.initials: K
authors.lastname: Ohtomo
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Miyashita
authors.forename: Seiki
authors.initials: S
authors.lastname: Konishi
mesh_terms: D000328:Adult; D001481:Basal Metabolism; D001921:Brain / Q000033:anatomy & histology / Q000378:metabolism / Q000502:physiology*; D001931:Brain Mapping / Q000379:methods*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D013997:Time Factors; D055815:Young Adult