title: PdCl2-catalyzed oxidative cycloisomerization of 3-cyclopropylideneprop-2-en-1-ones.
abstract: A novel PdCl(2)-catalyzed oxidative cycloisomerization of 3-cyclopropylideneprop-2-en-1-ones, providing a facile synthesis of highly strained functionalized 2-alkylidenecyclobutanones via furan-fused cyclobutene intermediates, is reported. An interesting route to 2(3H)-furanones with a spiro-cyclopropane unit from the obtained 2-alkylidenecyclobutanones via a ring-contraction rearrangement reaction is also realized.
authors.affiliation: Department of Chemistry, Zhejiang University, Hangzhou 310028, P. R. China.
authors.forename: Maozhong
authors.initials: M
authors.lastname: Miao
authors.forename: Jian
authors.initials: J
authors.lastname: Cao
authors.forename: Jingjing
authors.initials: J
authors.lastname: Zhang
authors.forename: Xian
authors.initials: X
authors.lastname: Huang
authors.forename: Luling
authors.initials: L
authors.lastname: Wu
mesh_terms: D000466:Alkadienes / Q000737:chemistry*; D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D003500:Cyclization; D003521:Cyclopropanes / Q000138:chemical synthesis* / Q000737:chemistry*; D005663:Furans / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000466:Alkadienes; D003521:Cyclopropanes; D005663:Furans; D010165:Palladium; C030797:cyclopropane; C008756:palladium chloride; C039281:furan