title: Molecular mapping of the acid catalysed dehydration of fructose.
abstract: Several intermediates and different reaction paths were identified for the acid catalysed conversion of fructose to 5-(hydroxymethyl)-2-furaldehyde (HMF) in different solvents. The structural information combined with results of isotopic-labelling experiments allowed the determination of the irreversibility of the three steps from the fructofuranosyl oxocarbenium ion to HMF as well as the analogous pyranose route.
authors.affiliation: Department of Biology and Chemistry, City University of Hong Kong, 83 Tat Chee Avenue, Kowloon, Hong Kong SAR.
authors.forename: Geoffrey R
authors.initials: GR
authors.lastname: Akien
authors.forename: Long
authors.initials: L
authors.lastname: Qi
authors.forename: István T
authors.initials: IT
authors.lastname: Horváth
mesh_terms: D002384:Catalysis; D003890:Desiccation; D005632:Fructose / Q000737:chemistry*; D005662:Furaldehyde / Q000031:analogs & derivatives* / Q000737:chemistry; D013464:Sulfuric Acids / Q000737:chemistry
chemical_list: D013464:Sulfuric Acids; D005632:Fructose; C008046:5-hydroxymethylfurfural; D005662:Furaldehyde; C033158:sulfuric acid