title: Application of ultrasound contrast in identification and diagnosis of ocular spaceoccupying lesions.
abstract: OBJECTIVE
  To analyze the application significance of ultrasound contrast agent in identification and diagnosis of ocular spaceoccupying lesions, and mainly analyze its advantages and problems.
  
  
  METHODS
  Thirty-two representative literatures about the application of ultrasound contrast agent in diagnosis of spaceoccupying lesions at home and abroad were collected after focused on sorting the literature reporting the application of ultrasound contrast diagnostic technology in the diagnosis and identification of ocular spaceoccupying lesions in recent years. Its advantages and problems were retrospectively analyzed, and reasonable assessment on existing problems was made and possible solutions to the problems were proposed.
  
  
  RESULTS
  As a new imaging diagnostic technique, the contrast-enhanced ultrasound, which can enhance the display of tumor microcirculation vessels and improve the tumor's ultrasound diagnostic capability, was analyzed. Through sorting and comprehensively analyzing the collected literatures, the positive rate of ocular spaceoccupying lesion diagnosis could be significantly improved with ultrasound contrast technology. Thus, the vascular perfusion in normal tissues and lesions was reflected objectively. According to the lesion's perfusion characteristics of the contrast agent plus with the performance features of two-dimensional ultrasound, the ocular spaceoccupying lesions can be accurately diagnosed, and this could provide clinicians with reliable research basis in this field.
  
  
  CONCLUSIONS
  Ultrasound contrast examination is a new testing method, and ultrasound contrast agent can significantly enhance the ultrasonic detection signal, clearly show the blood perfusion in vessels and tissues, increase the image contrast resolution, and improve the lesion's detection capability in the microcirculation perfusion level, especially its important value in the diagnosis of ocular tumor.
authors.affiliation: Department of Ultrasonography, Hospital of Military Area of He'nan Zhengzhou 450003, He'nan Province, China.
authors.forename: Jia-Ying
authors.initials: JY
authors.lastname: Yuan
authors.forename: Jian-Hua
authors.initials: JH
authors.lastname: Zhang
authors.forename: Chong
authors.initials: C
authors.lastname: Tang
authors.forename: Jing-Zhi
authors.initials: JZ
authors.lastname: Zhao
authors.forename: Chao
authors.initials: C
authors.lastname: Pang
authors.forename: Xin-Chun
authors.initials: XC
authors.lastname: Ren
authors.forename: Hong
authors.initials: H
authors.lastname: Zhu
authors.forename: Yun-Tao
authors.initials: YT
authors.lastname: Zhang