title: Knee joint neuromuscular activation performance during muscle damage and superimposed fatigue.
abstract: This study examined the concurrent effects of exercise-induced muscle damage and superimposed acute fatigue on the neuromuscular activation performance of the knee flexors of nine males (age: 26.7 ± 6.1 years; height 1.81 ± 0.05 m; body mass 81.2 ± 11.7 kg [mean±s]). Measures were obtained during three experimental conditions: (i) 'fatigue-muscle damage', involving acute fatiguing exercise performed on each assessment occasion plus a single episode of eccentric exercise performed on the first occasion and after the fatigue trial; (ii) 'fatigue', involving the fatiguing exercise only; and (iii) 'control' consisting of no exercise. Assessments were performed prior to (pre) and at 1 h, 24 h, 48 h, 72 h, and 168 h relative to the muscle damaging eccentric exercise. Repeated-measures analyses of variance (ANOVAs) showed that muscle damage elicited reductions of up to 38%, 24% and 65% in volitional peak force, electromechanical delay and rate of force development compared to baseline and controls, respectively (F ([10, 80]) = 2.3 to 4.6; P < 0.05) with further impairments (6.2% to 30.7%) following acute fatigue (F ([2, 16]) = 4.3 to 9.1; P < 0.05). By contrast, magnetically-evoked electromechanical delay was not influenced by muscle damage and was improved during the superimposed acute fatigue (∼14%; F ([2, 16]) = 3.9; P < 0.05). The safeguarding of evoked muscle activation capability despite compromised volitional performance might reveal aspects of capabilities for emergency and protective responses during episodes of fatigue and antecedent muscle damaging exercise.
authors.affiliation: Nottingham Trent University, School of Science and Technology, Clifton Lane, Nottingham, UK. claire.minshull@ntu.ac.uk
authors.forename: Claire
authors.initials: C
authors.lastname: Minshull
authors.forename: Roger
authors.initials: R
authors.lastname: Eston
authors.forename: David
authors.initials: D
authors.lastname: Rees
authors.forename: Nigel
authors.initials: N
authors.lastname: Gleeson
mesh_terms: D000328:Adult; D001265:Athletic Injuries / Q000097:blood / Q000503:physiopathology*; D003402:Creatine Kinase / Q000097:blood; D004576:Electromyography; D015444:Exercise / Q000502:physiology; D006801:Humans; D007719:Knee Joint / Q000503:physiopathology*; D008297:Male; D018763:Muscle Fatigue / Q000502:physiology*; D053580:Muscle Strength / Q000502:physiology; D018482:Muscle, Skeletal / Q000293:injuries* / Q000503:physiopathology; D055815:Young Adult
chemical_list: D003402:Creatine Kinase