title: [Prevalence of neuropsychiatric symptoms and associated factors in institutionalised dementia patients: A multicentre cross-sectional study].
abstract: OBJECTIVE
  The aim was to estimate the prevalence and severity of neuropsychiatric symptoms in patients with dementia in nursing homes, assessing their association with certain factors that may influence their occurrence.
  
  
  METHODS
  A cross-sectional study was carried out, and included all elderly patients diagnosed with degenerative, vascular, or mixed dementia, stage 4 to 7 on the Global Deterioration Scale of Reisberg (GDS), and residents in 6 nursing homes in the province of Ourense (Spain). A sample size of 120 individuals was determined to be necessary. The assessment of symptoms was performed using the Neuropsychiatric Inventory-Nursing Home test. The influence of the determined factors was investigated using logistic and linear regression analysis, and subsequently corrected for possible confounding factors.
  
  
  RESULTS
  A total of 212 cases were included, with a mean age of 85.7 (SD=6.7) years. The prevalence of neuropsychiatric symptoms was 84.4%. The most common symptom was apathy, followed by agitation and delirium, and the least frequent were euphoria and hallucinations. The symptom that produced most occupational disruption was agitation. Multivariate analysis showed that a higher score on the NPI-NH was associated with a higher score on the Global Deterioration Scale of Reisberg, the use of neuroleptics, cholinesterase inhibitors, and memantine.
  
  
  CONCLUSIONS
  In nursing home patients, prevalence of neuropsychiatric symptoms was high, and associated with the severity of dementia (GDS), the use of neuroleptics, cholinesterase inhibitors, and memantine.
authors.affiliation: Centro de Salud Xinzo de Limia, SERGAS, Ourense, España.
authors.forename: Aida
authors.initials: A
authors.lastname: Robles Castiñeiras
authors.forename: Gabriel J
authors.initials: GJ
authors.lastname: Díaz Grávalos
authors.forename: Santiago
authors.initials: S
authors.lastname: Reinoso Hermida
authors.forename: Ana
authors.initials: A
authors.lastname: López González
authors.forename: Carmen
authors.initials: C
authors.lastname: Vázquez Gil
authors.forename: Alejandro A
authors.initials: AA
authors.lastname: García Caballero
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002493:Central Nervous System Diseases / Q000150:complications* / Q000453:epidemiology*; D003430:Cross-Sectional Studies; D003704:Dementia / Q000150:complications*; D005260:Female; D006801:Humans; D008297:Male; D001523:Mental Disorders / Q000150:complications* / Q000453:epidemiology*; D015995:Prevalence; D012720:Severity of Illness Index