title: Visual and optical performance and quality of life after implantation of posterior chamber phakic intraocular lens.
abstract: OBJECTIVE
  To evaluate visual, optical, and quality of life (QoL) outcomes and intercorrelations after bilateral implantation of posterior chamber phakic intraocular lenses.
  
  
  METHODS
  Twenty eyes with high to moderate myopia of 10 patients that underwent PRL implantation (Phakic Refractive Lens, Carl Zeiss Meditec AG) were examined. Refraction, visual acuity, photopic and low mesopic contrast sensitivity (CS) with and without glare, ocular aberrations, as well as QoL outcomes (National Eye Institute Refractive Error Quality of Life Instrument-42, NEI RQL-42) were evaluated at 12 months postoperatively.
  
  
  RESULTS
  Significant improvement in uncorrected (UDVA) and best-corrected distance (CDVA) visual acuities were found postoperatively (p < 0.01), with significant reduction in spherical equivalent (p < 0.01). Low mesopic CS without glare was significantly better than measurements with glare for 1.5, 3, and 6 cycles/degree (p < 0.01). No significant correlations between higher order root mean square (RMS) with CDVA (r = -0.26, p = 0.27) and CS (r ≤ 0.45, p ≥ 0.05) were found. Postoperative binocular photopic CS for 12 cycles/degree and 18 cycles/degree correlated significantly with several RQL-42 scales. Glare index correlated significantly with CS measures and scotopic pupil size (r = -0.551, p = 0.04), but not with higher order RMS (r = -0.02, p = 0.94). Postoperative higher order RMS, postoperative primary coma and postoperative spherical aberration was significant higher for 5-mm pupil diameter (p < 0.01) compared with controls.
  
  
  CONCLUSIONS
  Correction of moderate to high myopia by means of PRL implantation had a positive impact on CS and QoL. The aberrometric increase induced by the surgery does not seem to limit CS and QoL. However, perception of glare is still a relevant disturbance in some cases possibly related to the limitation of the optical zone of the PRL.
authors.affiliation: Optometry Research Group, Department of Optics, University of Valencia, Dr. Moliner, 50, 46100 Burjassot, Valencia, Spain.
authors.forename: Rafael J
authors.initials: RJ
authors.lastname: Pérez-Cambrodí
authors.forename: Francisco J
authors.initials: FJ
authors.lastname: Blanes-Mompó
authors.forename: Santiago
authors.initials: S
authors.lastname: García-Lázaro
authors.forename: David P
authors.initials: DP
authors.lastname: Piñero
authors.forename: Alejandro
authors.initials: A
authors.lastname: Cerviño
authors.forename: Rune
authors.initials: R
authors.lastname: Brautaset
mesh_terms: D000328:Adult; D015350:Contrast Sensitivity / Q000502:physiology; D005260:Female; D005500:Follow-Up Studies; D019466:Glare; D006304:Health Status; D006801:Humans; D019654:Lens Implantation, Intraocular; D008297:Male; D008875:Middle Aged; D009216:Myopia / Q000503:physiopathology / Q000601:surgery*; D055095:Optics and Photonics; D054120:Phakic Intraocular Lenses; D011788:Quality of Life; D012029:Refraction, Ocular / Q000502:physiology; D018434:Sickness Impact Profile; D016896:Treatment Outcome; D014792:Visual Acuity / Q000502:physiology*