title: [Cerebral hemodynamic changes in hyperlipemia patients with transcranial Doppler].
abstract: OBJECTIVE
  To analyze cerebral hemodynamic changes by means of transcranial Doppler (TCD) and generally to explore the clinical application of this method in hyperlipemia patients.
  
  
  METHODS
  Cerebral hemodynamics were detected by TCD in 63 patients with hyperlipidemia and compared with the hemodynamics of 64 health people.
  
  
  RESULTS
  No statistically significant changes were found in the cerebral artery blood flow velocity and pulsatility index between the hyperlipidemic and control groups (P>0.05). Spectral shape, however, was abnormal in 52 patients in the hyperlipemia group (82.54%), which was statistically different (P<0.005) from controls. These abnormalities were classed as follows: 22 patients had abnormal spectra of the vertebrobasilar system, 2 patients had abnormal spectrum of the internal carotid arterial system, and 28 patients had abnormal spectra of both systems. The incidence of the abnormal spectra in vertebrobasilar system was significantly higher than the internal carotidartery (P<0.005).
  
  
  CONCLUSIONS
  TCD examination can reveal abnormal spectral shape in the cerebralartery and vertebrobasilar arterial systems in hyperlipidemia patients, and thus has some clinical value in determining changes in the brain of patients with high cholesterol levels and atherosclerosis.
authors.affiliation: Health Management Center, Xiangya Hospital, Central South Unversity, Changsha 410008, China. liyn596068@163.com
authors.forename: Yan
authors.initials: Y
authors.lastname: Li
authors.forename: Jinjin
authors.initials: J
authors.lastname: Fu
authors.forename: Ke
authors.initials: K
authors.lastname: Li
authors.forename: Fafa
authors.initials: F
authors.lastname: Tian
authors.forename: Qun
authors.initials: Q
authors.lastname: Qin
authors.forename: Mingyu
authors.initials: M
authors.lastname: Song
mesh_terms: D000328:Adult; D002560:Cerebrovascular Circulation / Q000502:physiology*; D005260:Female; D006439:Hemodynamics / Q000502:physiology*; D006801:Humans; D006949:Hyperlipidemias / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D017585:Ultrasonography, Doppler, Transcranial