title: Metastatic pulmonary adenocarcinoma 13 years after curative resection for pancreatic cancer: report of a case and review of Japanese literature.
abstract: BACKGROUND
  For the majority of patients, ductal adenocarcinoma of the pancreas remains a lethal disease. Currently, surgical extirpation for localized disease offers the only chance for long-term survival.
  
  
  METHODS
  We report a patient who underwent successful resection of isolated lung metastasis occurring 13 years after pancreatic cancer resection. A 59-year-old woman underwent distal pancreatectomy for pancreatic cancer 13 years previously, followed by adjuvant chemotherapy, and was followed-up at the outpatient clinic of a local hospital. From around June 2010, she noticed bloody sputum, so she visited a local hospital. Since her chest X-ray and CT revealed a 1.5 cm mass shadow in the segment 10 of her right lung and she was referred to the Respiratory Disease Center of our hospital. As a result of through examinations, she was strongly suspected of having lung metastasis of pancreatic cancer, and underwent partial pneumonectomy. Postoperative histopathological examination of the resected specimen was consistent with lung metastasis of pancreatic cancer. She is still alive and currently receives third line of chemotherapy.
  
  
  CONCLUSIONS
  Patients who have achieved long-term survival after pancreatic cancer resection and can tolerate surgery may benefit from resection of a lung metastasis of pancreatic cancer in terms of survival, if it controls the metastasis.
authors.affiliation: Department of Surgery, Kurume University School of Medicine, Kurume, Japan. kitasato_yuuhei@kurume-u.ac.jp
authors.forename: Yuhei
authors.initials: Y
authors.lastname: Kitasato
authors.forename: Masamichi
authors.initials: M
authors.lastname: Nakayama
authors.forename: Gen
authors.initials: G
authors.lastname: Akasu
authors.forename: Munehiro
authors.initials: M
authors.lastname: Yoshitomi
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Mikagi
authors.forename: Yuichiro
authors.initials: Y
authors.lastname: Maruyama
authors.forename: Ryuichi
authors.initials: R
authors.lastname: Kawahara
authors.forename: Hiroto
authors.initials: H
authors.lastname: Ishikawa
authors.forename: Toru
authors.initials: T
authors.lastname: Hisaka
authors.forename: Masafumi
authors.initials: M
authors.lastname: Yasunaga
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Horiuchi
authors.forename: Naoyuki
authors.initials: N
authors.lastname: Saito
authors.forename: Shinzo
authors.initials: S
authors.lastname: Takamori
authors.forename: Yoshinobu
authors.initials: Y
authors.lastname: Okabe
authors.forename: Masayoshi
authors.initials: M
authors.lastname: Kage
authors.forename: Hisafumi
authors.initials: H
authors.lastname: Kinoshita
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Tanaka
mesh_terms: D000230:Adenocarcinoma / Q000000981:diagnostic imaging* / Q000556:secondary* / Q000601:surgery; D005260:Female; D006801:Humans; D007564:Japan; D008175:Lung Neoplasms / Q000000981:diagnostic imaging* / Q000556:secondary* / Q000601:surgery; D008875:Middle Aged; D010180:Pancreatectomy; D010190:Pancreatic Neoplasms / Q000473:pathology* / Q000601:surgery*; D011013:Pneumonectomy; D013902:Radiography, Thoracic; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome