title: Persistent erythematous plaque after minor trauma in an immunocompromised woman.
abstract: Scedosporium apiospermum is a ubiquitous soil fungus with a worldwide distribution. It can cause a wide range of clinical disease, from cutaneous and subcutaneous infections, to pneumonia, brain abscess, and life threatening systemic illness. The diagnosis of cutaneous disease is with biopsy and culture. We discuss the case of an elderly immunocompromised woman who presented with a persistent erythematous plaque on the elbow after minor trauma. A biopsy revealed Scedosporium apiospermum. Treatment usually requires surgical resection in conjunction with antifungal therapy.
authors.affiliation: Center for Clinical Studies, Webster, Texas, USA.
authors.forename: Rana
authors.initials: R
authors.lastname: Mays
authors.forename: Rachel
authors.initials: R
authors.lastname: Gordon
authors.forename: Janice M
authors.initials: JM
authors.lastname: Wilson
authors.forename: Whitney J
authors.initials: WJ
authors.lastname: LaPolla
authors.forename: Karan K
authors.initials: KK
authors.lastname: Sra
authors.forename: Vandana
authors.initials: V
authors.lastname: Madkan
authors.forename: Stephen K
authors.initials: SK
authors.lastname: Tyring
mesh_terms: D000369:Aged, 80 and over; D000935:Antifungal Agents / Q000627:therapeutic use; D001134:Arm Injuries / Q000382:microbiology*; D003881:Dermatomycoses / Q000188:drug therapy / Q000382:microbiology* / Q000473:pathology; D005260:Female; D006801:Humans; D016867:Immunocompromised Host; D009281:Naphthalenes / Q000627:therapeutic use; D021681:Scedosporium; D000077291:Terbinafine; D014946:Wound Infection / Q000382:microbiology*
chemical_list: D000935:Antifungal Agents; D009281:Naphthalenes; D000077291:Terbinafine