title: Correlation between body fat distribution, plasma lipids and apolipoproteins with the severity of coronary involvement in patients with stable angina.
abstract: BACKGROUND
  Previous studies reported that the distribution of body fat is an important risk factor for coronary artery diseases (CAD) and abdominal adipose tissue is associated with severe CAD. This study was conducted to evaluate the relationship between body fat distributions, plasma lipids and the severity of CAD in patients with stable angina.
  
  
  METHODS
  NINETY SEVEN PATIENTS WHO UNDERWENT CORONARY ANGIOGRAPHY FOR STABLE ANGINA WERE ALLOCATED INTO TWO GROUPS: patients with mild or sever coronary artery involvement. Lipid profile (total cholesterol, LDL, HDL) and triglyceride (TG) and apolipoprotein A and B, were measured for all of the participants and a demographic data questionnaire was filled by the subjects. Participants underwent abdominal computed tomography (CT-Scan) for measurement of adipose tissues that was classified to visceral and superficial and deep subcutaneous fat tissue compartment.
  
  
  RESULTS
  Patients with severe coronary artery involvement had higher level of apo B (P=0.02). Significant correlation was seen between visceral fat index and TG (P=0.01), HDL-C (P<0.01) in patients with mild coronary involvement and with total cholesterol (P=0.02), LDL-C (P=0.01) and apoB (P<0.01) in patients with severe coronary involvement.No significant relationship was seen among deep cutaneous fat index and lipid profile in both groups.
  
  
  CONCLUSIONS
  Our findings showed that visceral adipose tissue is significantly associated with severe CAD and has a significant correlation with lipid profile as well as Apo B.
authors.affiliation: Resident of Cardiology, Isfahan University of Medical Sciences, Isfahan, Iran.
authors.forename: Shahram
authors.initials: S
authors.lastname: Mazaheri
authors.forename: Masoumeh
authors.initials: M
authors.lastname: Sadeghi
authors.forename: Nizal
authors.initials: N
authors.lastname: Sarrafzadegan
authors.forename: Hamid
authors.initials: H
authors.lastname: Sanei
authors.forename: Ali
authors.initials: A
authors.lastname: Hekmatnia
authors.forename: Babak
authors.initials: B
authors.lastname: Tavakoli