title: Prevalence of autoantibodies in a group of hereditary angioedema patients.
abstract: Hereditary Angioedema is a dominantly inherited disease. Routine screening of autoantibodies (AAB) is not recommended for individuals with Hereditary Angioedema; however, prevalence of these antibodies in Hereditary Angioedema patients is not well documented. We aim to determine the prevalence of AAB so that individuals at risk of developing autoimmune diseases can be identified. Fifteen patients with Hereditary Angioedema attended at Clementino Fraga Filho University Hospital accepted to participate in this study. Prevalence of AAB was 40%. Our data indicate high prevalence of AAB in patients with Hereditary Angioedema. Large-scale studies should be considered to determine the significance of these AAB in the follow-up care of patients with Hereditary Angioedema.
authors.affiliation: Internal Medicine, Hospital Geral de Nova Iguaçu, Nova Iguaçu, RJ, Brazil. sdortasjr@gmail.com
authors.forename: Sergio Duarte
authors.initials: SD
authors.lastname: Dortas Junior
authors.forename: Solange Oliveira Rodrigues
authors.initials: SO
authors.lastname: Valle
authors.forename: Soloni Afra Pires
authors.initials: SA
authors.lastname: Levy
authors.forename: Rosangela P
authors.initials: RP
authors.lastname: Tortora
authors.forename: Augusto Tiaqui
authors.initials: AT
authors.lastname: Abe
authors.forename: Gisele Viana
authors.initials: GV
authors.lastname: Pires
authors.forename: José Angelo de Souza
authors.initials: JA
authors.lastname: Papi
authors.forename: Alfeu Tavares
authors.initials: AT
authors.lastname: França
mesh_terms: D000328:Adult; D054179:Angioedemas, Hereditary / Q000276:immunology*; D001323:Autoantibodies / Q000097:blood*; D005260:Female; D006801:Humans; D008297:Male; D015995:Prevalence
chemical_list: D001323:Autoantibodies