title: [Atypical choroid plexus papilloma in adults: case report and literature review].
abstract: BACKGROUND
  Atypical choroid plexus papilloma is a rare tumour, recently defined by the World Health Organisation and with very few cases reported to date. Choroid plexus tumours are rare intraventricular neoplasms originating from choroid plexus epithelium, with benign papillomas being more frequent than carcinomas. Most of these lesions appear in children, mainly located in the lateral ventricles. Those arising from the fourth ventricle are more frequent in adulthood. Surgery with complete resection can be curative in papillomas, with 5-year survival rates close to 100% and occasional recurrences. Radical surgery in carcinomas is difficult and usually requires adjuvant therapy, prognosis is worse and survival rates are lower. We report a case of atypical choroid plexus papilloma in adulthood located in the fourth ventricle, describing the different therapeutic options and reviewing the existing literature.
  
  
  METHODS
  38-year old male with an atypical choroid plexus papilloma located in the fourth ventricle, totally resected by posterior fossa craniectomy and telovellar approach.
  
  
  CONCLUSIONS
  Atypical choroid plexus papillomas are associated with an increased risk of recurrence or malignant transformation when compared to "typical" papillomas. At present, complete surgical excision and close follow-up seems to be the most reliable treatment. Adjuvant chemotherapy or radiotherapy should be considered in cases of partial resection, recurrence or dissemination.
authors.affiliation: Servicio de Neurocirugía, Hospital Universitario de Getafe, Madrid, España.
authors.forename: Ignacio
authors.initials: I
authors.lastname: Jusué-Torres
authors.forename: José Manuel
authors.initials: JM
authors.lastname: Ortega-Zufiría
authors.forename: Martin
authors.initials: M
authors.lastname: Tamarit-Degenhardt
authors.forename: Pedro Domingo
authors.initials: PD
authors.lastname: Poveda-Núñez
mesh_terms: D000328:Adult; D002277:Carcinoma; D002551:Cerebral Ventricle Neoplasms; D016545:Choroid Plexus Neoplasms; D005910:Glioma; D006801:Humans; D009364:Neoplasm Recurrence, Local / Q000601:surgery; D020288:Papilloma, Choroid Plexus