title: Italian guidelines for primary headaches: 2012 revised version.
abstract: The first edition of the Italian diagnostic and therapeutic guidelines for primary headaches in adults was published in J Headache Pain 2(Suppl. 1):105-190 (2001). Ten years later, the guideline committee of the Italian Society for the Study of Headaches (SISC) decided it was time to update therapeutic guidelines. A literature search was carried out on Medline database, and all articles on primary headache treatments in English, German, French and Italian published from February 2001 to December 2011 were taken into account. Only randomized controlled trials (RCT) and meta-analyses were analysed for each drug. If RCT were lacking, open studies and case series were also examined. According to the previous edition, four levels of recommendation were defined on the basis of levels of evidence, scientific strength of evidence and clinical effectiveness. Recommendations for symptomatic and prophylactic treatment of migraine and cluster headache were therefore revised with respect to previous 2001 guidelines and a section was dedicated to non-pharmacological treatment. This article reports a summary of the revised version published in extenso in an Italian version.
authors.affiliation: Headache Centre, Neurologic Clinic, University of Perugia, Perugia, Italy. paola.sarchielli@gmail.com
authors.forename: Paola
authors.initials: P
authors.lastname: Sarchielli
authors.forename: Franco
authors.initials: F
authors.lastname: Granella
authors.forename: Maria Pia
authors.initials: MP
authors.lastname: Prudenzano
authors.forename: Luigi Alberto
authors.initials: LA
authors.lastname: Pini
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Guidetti
authors.forename: Giorgio
authors.initials: G
authors.lastname: Bono
authors.forename: Lorenzo
authors.initials: L
authors.lastname: Pinessi
authors.forename: Massimo
authors.initials: M
authors.lastname: Alessandri
authors.forename: Fabio
authors.initials: F
authors.lastname: Antonaci
authors.forename: Marcello
authors.initials: M
authors.lastname: Fanciullacci
authors.forename: Anna
authors.initials: A
authors.lastname: Ferrari
authors.forename: Mario
authors.initials: M
authors.lastname: Guazzelli
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Nappi
authors.forename: Grazia
authors.initials: G
authors.lastname: Sances
authors.forename: Giorgio
authors.initials: G
authors.lastname: Sandrini
authors.forename: Lidia
authors.initials: L
authors.lastname: Savi
authors.forename: Cristina
authors.initials: C
authors.lastname: Tassorelli
authors.forename: Giorgio
authors.initials: G
authors.lastname: Zanchin
mesh_terms: D016206:Databases, Bibliographic / Q000706:statistics & numerical data; D051270:Headache Disorders, Primary / Q000175:diagnosis / Q000188:drug therapy / Q000517:prevention & control; D006801:Humans; D007558:Italy; D015201:Meta-Analysis as Topic; D017410:Practice Guidelines as Topic / Q000592:standards*; D016032:Randomized Controlled Trials as Topic; D012955:Societies, Medical / Q000592:standards