title: Cu(II)-catalyzed C-H (SP3) oxidation and C-N cleavage: base-switched methylenation and formylation using tetramethylethylenediamine as a carbon source.
abstract: Base-switched methylenation and formylation using tetramethylethylenediamine (TMEDA) as a carbon source have been achieved under mild conditions, catalyzed by CuCl(2), with atmospheric oxygen as oxidant. Bisindolylmethanes, diphenylmethanes and 3-formylindoles were synthesized with excellent regioselectivity and good yield.
authors.affiliation: State Key Lab of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, 210093, P. R. China.
authors.forename: Lei
authors.initials: L
authors.lastname: Zhang
authors.forename: Chen
authors.initials: C
authors.lastname: Peng
authors.forename: Dan
authors.initials: D
authors.lastname: Zhao
authors.forename: Yue
authors.initials: Y
authors.lastname: Wang
authors.forename: Hai-Jian
authors.initials: HJ
authors.lastname: Fu
authors.forename: Qi
authors.initials: Q
authors.lastname: Shen
authors.forename: Jian-Xin
authors.initials: JX
authors.lastname: Li