title: Pheochromocytoma and paraganglioma: imaging characteristics.
abstract: The accurate diagnosis of adult pheochromocytoma and paraganglioma necessitates a multidisciplinary approach that includes clinical history, biochemical testing, and multimodality imaging such as computed tomography, magnetic resonance imaging, and nuclear medicine studies. This review illustrates the different imaging characteristics of primary adult pheochromocytomas as well as both sympathetic and parasympathetic paragangliomas. The review also describes known genetic associations and shows common metastatic patterns. Knowledge of the diverse appearance of pheochromocytomas and paragangliomas can result in early initial diagnosis or detection of disease recurrence thereby affecting patient management and prognosis.
authors.affiliation: Department of Radiology, Brigham and Women's Hospital, Boston, MA, USA. jcbaez@gmail.com
authors.forename: Juan C
authors.initials: JC
authors.lastname: Baez
authors.forename: Jyothi P
authors.initials: JP
authors.lastname: Jagannathan
authors.forename: Katherine
authors.initials: K
authors.lastname: Krajewski
authors.forename: Kevin
authors.initials: K
authors.lastname: O'Regan
authors.forename: Katherine
authors.initials: K
authors.lastname: Zukotynski
authors.forename: Matthew
authors.initials: M
authors.lastname: Kulke
authors.forename: Nikhil H
authors.initials: NH
authors.lastname: Ramaiya
mesh_terms: D000310:Adrenal Gland Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000235:genetics / Q000473:pathology; D014408:Biomarkers, Tumor / Q000097:blood / Q000652:urine; D003287:Contrast Media; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D009362:Neoplasm Metastasis; D009386:Neoplastic Syndromes, Hereditary / Q000175:diagnosis / Q000235:genetics / Q000473:pathology; D010235:Paraganglioma / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000235:genetics / Q000473:pathology; D010673:Pheochromocytoma / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000235:genetics / Q000473:pathology; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals; D012983:Soft Tissue Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000235:genetics / Q000473:pathology; D015899:Tomography, Emission-Computed, Single-Photon; D014057:Tomography, X-Ray Computed
chemical_list: D014408:Biomarkers, Tumor; D003287:Contrast Media; D019275:Radiopharmaceuticals