title: Linking neurogenetics and individual differences in language learning: the dopamine hypothesis.
abstract: Fundamental advances in neuroscience have come from investigations into neuroplasticity and learning. These investigations often focus on identifying universal principles across different individuals of the same species. Increasingly, individual differences in learning success have also been observed, such that any seemingly universal principle might only be applicable to a certain extent within a particular learner. One potential source of this variation is individuals' genetic differences. Adult language learning provides a unique opportunity for understanding individual differences and genetic bases of neuroplasticity because of the large individual differences in learning success that have already been documented, and because of the body of empirical work connecting language learning and neurocognition. In this article, we review the literature on the genetic bases of neurocognition, especially studies examining polymorphisms of dopamine (DA)-related genes and procedural learning. This review leads us to hypothesize that there may be an association between DA-related genetic variation and language learning differences. If this hypothesis is supported by future empirical findings we suggest that it may point to neurogenetic markers that allow for language learning to be personalized.
authors.affiliation: Roxelyn and Richard Pepper Department of Communication Sciences & Disorders, Northwestern University, Evanston, IL, USA. pwong@northwestern.edu
authors.forename: Patrick C M
authors.initials: PC
authors.lastname: Wong
authors.forename: Kara
authors.initials: K
authors.lastname: Morgan-Short
authors.forename: Marc
authors.initials: M
authors.lastname: Ettlinger
authors.forename: Jing
authors.initials: J
authors.lastname: Zheng
mesh_terms: D000818:Animals; D004298:Dopamine / Q000235:genetics / Q000378:metabolism*; D006801:Humans; D007206:Individuality; D007802:Language; D007804:Language Development; D007858:Learning / Q000502:physiology*; D009473:Neuronal Plasticity / Q000235:genetics*
chemical_list: D004298:Dopamine