title: [Effectiveness comparison between pedicle subtraction osteotomy and non-osteotomy techniques in treatment of medium-to-severe kyphoscoliosis].
abstract: OBJECTIVE
  To evaluate the effectiveness of pedicle subtraction osteotomy (PSO) and non-osteotomy techniques in treatment of medium-to-severe kyphoscoliosis by retrospective studies.
  
  
  METHODS
  Between January 2005 and January 2009, 99 patients with medium-to-severe kyphoscoliosis were treated by PSO (PSO group, n = 46) and non-osteotomy technique (non-osteotomy group, n = 53) separately. There was no significant difference in sex, age, Cobb angle of scoliosis on coronal plane, and Cobb angle of kyphosis on saggital plane between 2 groups (P > 0.05). The operation time and blood loss were recorded; the Cobb angle of scoliosis on coronal plane and kyphosis on sagittal plane were measured at pre- and postoperation to caculate the rates of correction on both planes.
  
  
  RESULTS
  The operation was successfully completed in all the patients. The operation time and blood loss of the patients in PSO group were significantly greater than those of the patients in non-osteotomy group (P < 0.05). All patients were followed up 12-56 months (mean, 22.4 months); no spinal cord injury occurred, and bone fusion was achieved at last follow-up. The Cobb angles of scoliosis and kyphosis at 2 weeks and last follow-up were significantly improved when compared with the preoperative angles in the patients of 2 groups (P < 0.05). There was no significant difference in Cobb angle of scoliosis and the rate of correction between 2 groups (P > 0.05), but the correction loss of PSO group was significantly smaller than that of non-osteotomy group (P < 0.05) at last follow-up. At 2 weeks and last follow-up, the Cobb angle of kyphosis, the rate of correction, and correction loss were significantly better in PSO group than in non-osteotomy group (P < 0.05).
  
  
  CONCLUSIONS
  There is no signifcant difference in scoliosis correction between PSO and non-osteotomy techniques. PSO can get better corrective effect in kyphosis correction than non-osteotomy technique, but the operation time and blood loss would increase greatly.
authors.affiliation: Spine Centre of Chinese PLA, the 306th Hospital of Chinese PLA, Beijing, 100101, P.R. China.
authors.forename: Jianwei
authors.initials: J
authors.lastname: Zhou
authors.forename: Jinsheng
authors.initials: J
authors.lastname: Peng
authors.forename: Bin
authors.initials: B
authors.lastname: Yang
authors.forename: Jing
authors.initials: J
authors.lastname: Niu
authors.forename: Zhiming
authors.initials: Z
authors.lastname: Chen
authors.forename: Xiaoping
authors.initials: X
authors.lastname: Wang
authors.forename: Jia
authors.initials: J
authors.lastname: Li
authors.forename: Huasong
authors.initials: H
authors.lastname: Ma
mesh_terms: D000293:Adolescent; D000328:Adult; D016063:Blood Loss, Surgical; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007738:Kyphosis / Q000473:pathology / Q000601:surgery*; D008159:Lumbar Vertebrae / Q000473:pathology / Q000601:surgery*; D008297:Male; D019637:Orthopedic Procedures / Q000379:methods; D010027:Osteotomy / Q000379:methods*; D011183:Postoperative Complications; D012189:Retrospective Studies; D012600:Scoliosis / Q000473:pathology / Q000601:surgery*; D012720:Severity of Illness Index; D013123:Spinal Fusion / Q000379:methods; D013904:Thoracic Vertebrae / Q000473:pathology / Q000601:surgery*; D013997:Time Factors; D016896:Treatment Outcome; D055815:Young Adult