title: Visual acuity loss and OCT changes as initial signs of leukaemia.
abstract: OBJECTIVE
  To report two cases where decreased visual acuity was the first symptom of leukaemia and optical coherence tomography (OCT) allowed identification and localization of the retinal lesions.
  
  
  METHODS
  Retrospective, interventional, case reports.
  
  
  RESULTS
  One case of lymphoblastic acute leukaemia and chronic lymphoid leukaemia were diagnosed following decreased visual acuity. OCT showed macular serous detachment in the first case. The second case presented hypo fluorescent retinal infiltrates which appeared as hyper reflective lesions by OCT. Retinal changes disappeared and visual acuity was recovered following complete remission of the neoplasm.
  
  
  CONCLUSIONS
  OCT is a valuable, non invasive diagnostic tool permitting detection, localization and follow-up of ocular dissemination of neoplasms.
authors.affiliation: Department of Ophthalmology and Albacete Hospital, Castilla La Mancha University. Albacete. Spain.
authors.forename: Jose M
authors.initials: JM
authors.lastname: Ortiz
authors.forename: Jose M
authors.initials: JM
authors.lastname: Ruiz-Moreno
authors.forename: Paola
authors.initials: P
authors.lastname: Pozo-Martos
authors.forename: Javier A
authors.initials: JA
authors.lastname: Montero