title: Glycemic control and survival in peritoneal dialysis patients with diabetes mellitus.
abstract: OBJECTIVE
  The optimal target for glycated hemoglobin (HbA1c) has not been well defined in peritoneal dialysis (PD) patients with diabetes mellitus.
  
  
  METHODS
  The objective of our study was to examine the predictive value of predialysis and time-averaged follow-up HbA1c values on technique and patient survival in diabetic PD patients treated in the Toronto General Hospital Home Peritoneal Dialysis Unit, between January 1, 2003 and December 31, 2008 with a median follow-up period of 30±23 months.
  
  
  RESULTS
  Ninety-one patients (mean age 64±13 years-old) were included in this retrospective study. Patients were followed between 3 and 91 months (mean duration 30±23 months). During this period, 40 patients died. We found no statistically significant correlation between baseline predialysis HbA1c values and technique and patient survival. Time-averaged follow-up HbA1c in increments<6.5%, 6.5-8%, and >8% showed no significant survival difference among groups.
  
  
  CONCLUSIONS
  There was no significant correlation of baseline and time-averaged follow-up HbA1c values with patient and PD technique survival.
authors.affiliation: The Home Peritoneal Dialysis Unit, Toronto General Hospital, University Health Network and University of Toronto, 200 Elizabeth Street, 8N-840, Toronto, ON, M5G 2C4, Canada.
authors.forename: Nigar
authors.initials: N
authors.lastname: Sekercioglu
authors.forename: Chrysostomos
authors.initials: C
authors.lastname: Dimitriadis
authors.forename: Chrysoula
authors.initials: C
authors.lastname: Pipili
authors.forename: Rosilene Motta
authors.initials: RM
authors.lastname: Elias
authors.forename: Joseph
authors.initials: J
authors.lastname: Kim
authors.forename: Dimitrios G
authors.initials: DG
authors.lastname: Oreopoulos
authors.forename: Joanne M
authors.initials: JM
authors.lastname: Bargman
mesh_terms: D000368:Aged; D001786:Blood Glucose / Q000032:analysis*; D003920:Diabetes Mellitus / Q000097:blood*; D003928:Diabetic Nephropathies / Q000097:blood* / Q000401:mortality* / Q000628:therapy; D005260:Female; D006442:Glycated Hemoglobin / Q000032:analysis*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010530:Peritoneal Dialysis / Q000401:mortality*; D011237:Predictive Value of Tests; D012189:Retrospective Studies; D015996:Survival Rate
chemical_list: D001786:Blood Glucose; D006442:Glycated Hemoglobin