title: [Clinical significance of (18)F-FDG PET/CT evaluation of response to treatment in T-cell lymphoma].
abstract: OBJECTIVE
  To investigate the usefulness of (18)F-FDG PET/CT imaging in restaging, evaluating the treatment outcome, monitoring relapse and predicting prognosis of T-cell lymphoma.
  
  
  METHODS
  Retrospective analysis of PET/CT image results of thirty-four patients with T-cell lymphoma, and to evaluate its clinical significance in restaging, treatment efficiency, relapse monitor and prognosis prediction.
  
  
  RESULTS
  Clinical restaging among the 20 stage I and II patients, 6 were ascended, 9 descended and 5 unchanged. Restaging among the other 14 stage III and IV patients, 3 were ascended, 4 descended and 7 unchanged. There were 12 patients in complete remission (CR), 11 in partial remission (PR), 2 in stable disease (SD) and 9 in progressive disease (PD) among all the 34 patients. There is obvious statistical difference of the standardized uptake value (SUV) between the efficacy group and the inefficacy group after treatment of 6 courses at least in 25 patients among all the 34 patients (P = 0.009). There is obvious statistical difference of the SUV value before and after treatment in 8 patients among all the 34 patients (P = 0.000). There is obvious statistical difference in the survival time between the efficacy group and the inefficacy group after treatment of 6 courses at least in 25 patients among all the 34 patients (P = 0.015).
  
  
  CONCLUSIONS
  (18)F-FDG PET/CT imaging plays an very important role in guiding clinical restaging, evaluating the treatment outcome, monitoring relapse and predicting prognosis of T-cell lymphoma. It is helpful to establish personalized treatment planning.
authors.affiliation: Department of Molecule Image and Nuclear Medicine to Diagnose and Treatment, Tianjin Medical University, Tianjin, China.
authors.forename: Juan
authors.initials: J
authors.lastname: Cheng
authors.forename: Xiao-yi
authors.initials: XY
authors.lastname: Yang
authors.forename: Wen-gui
authors.initials: WG
authors.lastname: Xu
authors.forename: Xiu-yu
authors.initials: XY
authors.lastname: Song
authors.forename: Dong
authors.initials: D
authors.lastname: Dai
authors.forename: Yan-jia
authors.initials: YJ
authors.lastname: Zhu
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D016399:Lymphoma, T-Cell / Q000000981:diagnostic imaging* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D049268:Positron-Emission Tomography / Q000379:methods*; D011379:Prognosis; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed / Q000379:methods*; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D019788:Fluorodeoxyglucose F18