title: A new automatic baseline correction method based on iterative method.
abstract: A new automatic baseline correction method for Nuclear Magnetic Resonance (NMR) spectra is presented. It is based on an improved baseline recognition method and a new iterative baseline modeling method. The presented baseline recognition method takes advantages of three baseline recognition algorithms in order to recognize all signals in spectra. While in the iterative baseline modeling method, besides the well-recognized baseline points in signal-free regions, the 'quasi-baseline points' in the signal-crowded regions are also identified and then utilized to improve robustness by preventing the negative regions. The experimental results on both simulated data and real metabolomics spectra with over-crowded peaks show the efficiency of this automatic method.
authors.affiliation: Department of Physics, Huazhong University of Science and Technology, Wuhan 430074, People's Republic of China.
authors.forename: Qingjia
authors.initials: Q
authors.lastname: Bao
authors.forename: Jiwen
authors.initials: J
authors.lastname: Feng
authors.forename: Fang
authors.initials: F
authors.lastname: Chen
authors.forename: Wenping
authors.initials: W
authors.lastname: Mao
authors.forename: Zao
authors.initials: Z
authors.lastname: Liu
authors.forename: Kewen
authors.initials: K
authors.lastname: Liu
authors.forename: Chaoyang
authors.initials: C
authors.lastname: Liu