title: Putralone, a novel 10alpha-hydroxy-25-nor D:A friedo-oleanane triterpenoid from Putranjiva roxburghii.
abstract: Chemical investigation of the leaves of Putranjiva roxburghii has resulted in the isolation of two new triterpenoids, putralone, a novel 10alpha-hydroxy-25-nor D:A friedo-olean-9(11)-en-3 one and 3beta-acetoxy-cycloart-24-en-23-one, along with a rare hopanoid, adian-5-en-3beta,29-diol. Other known triterpenoids isolated from this plant are 3beta-acetoxy-adian-5-ene, putrol, putrone, putranjivadione, roxburghonic acid, friedelin, friedlan-3alpha-ol, oleanolic acid and erythrodiol. Interestingly, putralone is the first example of a naturally occurring nor friedo-oleanane triterpenoid having a hydroxyl functionality at the C-10 position.
authors.affiliation: Chemistry Division, Indian Institute of Chemical Biology, 4, Raja S.C. Mullick Road, Jadavpur, Kolkata-700032, India.
authors.forename: Tulika
authors.initials: T
authors.lastname: Mukherjee
authors.forename: Tapas
authors.initials: T
authors.lastname: Sarkar
authors.forename: Piyali
authors.initials: P
authors.lastname: Paul
authors.forename: Ajit K
authors.initials: AK
authors.lastname: Chakraborty
authors.forename: Parasuraman
authors.initials: P
authors.lastname: Jaisankar
authors.forename: Siba Brata
authors.initials: SB
authors.lastname: Mukhopadhyay
mesh_terms: D019665:Euphorbiaceae / Q000737:chemistry*; D015394:Molecular Structure; D009828:Oleanolic Acid / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification*
chemical_list: D014315:Triterpenes; C572485:putralone; D009828:Oleanolic Acid