title: A 3D graphical representation of protein sequences based on the Gray code.
abstract: Based on the order of 6-bit binary Gray code, a cyclic order of 20 amino acids is introduced. A novel 3D graphical representation of protein sequences is proposed according to the CGR of DNA sequences. Furthermore, the mathematical descriptor is suggested to characterize the graphical representation curve. The efficiency of our approach can be illustrated by performing the comparison of similarities/dissimilarities among sequences of the ND5 proteins of nine different species. With the correlation and significance analysis, the comparisons of both our results and results of other graphical representation with the ClustalW's results can show the utility of our approach.
authors.affiliation: College of Science, Zhejiang Sci-Tech University, Hangzhou 310018, PR China. pinganhe@zstu.edu.cn
authors.forename: Ping-an
authors.initials: PA
authors.lastname: He
authors.forename: Dan
authors.initials: D
authors.lastname: Li
authors.forename: Yanping
authors.initials: Y
authors.lastname: Zhang
authors.forename: Xin
authors.initials: X
authors.lastname: Wang
authors.forename: Yuhua
authors.initials: Y
authors.lastname: Yao
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D019295:Computational Biology / Q000379:methods; D005815:Genetic Code; D006801:Humans; D008958:Models, Molecular; D011506:Proteins / Q000235:genetics*; D016415:Sequence Alignment; D020539:Sequence Analysis, Protein / Q000379:methods; D013045:Species Specificity
chemical_list: D011506:Proteins