title: [Yimusake alone or combined with trazodone hydrochloride for primary premature ejaculation].
abstract: OBJECTIVE
  To study the clinical effects of the Chinese drug Yimusake, used alone or in combination with trazodone hydrochloride, on primary premature ejaculation (PE).
  
  
  METHODS
  Sixty-eight primary PE patients were randomized to a control (n=32) and an experimental group (n=36), the former treated with Yimusake 1 tablet (50 mg) pre day, and the latter with 1 tablet of trazodone hydrochloride (50 mg) pre day in addition, both given orally after supper and for 4 weeks, followed by observation of the therapeutic effects.
  
  
  RESULTS
  Eighteen cases (56.25%) responded in the control and 25 (69.44% ) in the experimental group, with statistically significant difference between the two groups (P<0.05).
  
  
  CONCLUSIONS
  Yimusake combined with trazodone hydrochloride is highly efficacious for primary PE.
authors.affiliation: Department of Urology, The First Affiliated Hospital, Shanxi Medical University, Taiyuan, Shanxi 030001, China. x5j3x5@126.com
authors.forename: Ji-Xiu
authors.initials: JX
authors.lastname: Xu
authors.forename: Guo
authors.initials: G
authors.lastname: Gao
authors.forename: Ning
authors.initials: N
authors.lastname: Xu
authors.forename: Yun-Yun
authors.initials: YY
authors.lastname: Yang
mesh_terms: D000328:Adult; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D006801:Humans; D055048:Integrative Medicine; D008297:Male; D008517:Phytotherapy; D061686:Premature Ejaculation / Q000188:drug therapy*; D014196:Trazodone / Q000627:therapeutic use*; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D004365:Drugs, Chinese Herbal; D014196:Trazodone