title: Natural orifice transluminal endoscopic surgery in surgical oncology: analysis of indications and feasibility in cancer patients.
abstract: OBJECTIVE
  Natural orifice endoscopic surgery (NOTES) is an emerging technique that has been postulated as a promising alternative to laparoscopy in the field of minimal invasive surgery. Until now appropriate indications, safe access routes and general feasibility of this approach have not been defined exactly in surgical oncology.
  
  
  METHODS
  A total of 474 patients undergoing cancer surgery were analyzed regarding possible applications of transluminal endoscopic surgery. Patient with potential indications underwent intraoperative endoscopy to evaluate technical aspects, indications and intraoperative feasibility.
  
  
  RESULTS
  A potential indication for transluminal surgery was found in 54 of 474 patients (11%) undergoing abdominal cancer surgery. Staging of gastrointestinal tumors was considered the main indication (45%) followed by splenectomy (11%) and diagnostic excision (11%). As a potential access route the transgastric approach was considered in 42 patients (66%) and the transcolonic approach in 18 patients (28 %). Of these 42 patients, 19 (30%) presented with significant intra-abdominal adhesions which would have resulted in a more complicated procedure. Accurate transluminal orientation was considered impossible in 13 cases (20%).
  
  
  CONCLUSIONS
  Although some indications for NOTES procedures in surgical oncology have been identified in this study these techniques have to be assessed cautiously. Implementation of NOTES in surgical oncology is currently difficult because of technical problems, lack of intraoperative orientation and abdominal adhesions.
authors.affiliation: Department of General-, Visceral- and Transplantation Surgery, University Medicine, Berlin, Germany.
authors.forename: Sascha Santosh
authors.initials: SS
authors.lastname: Chopra
authors.forename: Karl
authors.initials: K
authors.lastname: Mrak
authors.forename: Peter
authors.initials: P
authors.lastname: Warnick
authors.forename: Michael
authors.initials: M
authors.lastname: Huenerbein
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D008297:Male; D008495:Medical Oncology; D008875:Middle Aged; D057605:Natural Orifice Endoscopic Surgery / Q000379:methods*; D009369:Neoplasms / Q000601:surgery*