title: Capturing the finer points of gene expression in psoriasis: beaming in on the CCL19/CCR7 axis.
abstract: Laser capture microdissection-coupled complementary DNA microarray analysis is a powerful tool for studying minor cell populations in tissues. In this issue, Mitsui et al. use this method to characterize the immune infiltrates that localize in the dermis of psoriatic skin. They identify the T-cell activation regulators C-C chemokine ligand 19 and C-C chemokine receptor 7 as potential mediators of immune organization in psoriasis.
authors.affiliation: Department of Dermatology, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA. lrittie@umich.edu
authors.forename: Laure
authors.initials: L
authors.lastname: Rittié
authors.forename: James T
authors.initials: JT
authors.lastname: Elder
mesh_terms: D020405:Dermis / Q000473:pathology*; D006801:Humans; D061346:Laser Capture Microdissection / Q000379:methods*; D020411:Oligonucleotide Array Sequence Analysis / Q000379:methods*; D011565:Psoriasis / Q000235:genetics* / Q000473:pathology*