title: Donors with renal artery stenosis: fit to donate.
abstract: Kidney donation from hypertensive donors is now an accepted norm in live related kidney transplantation. The use of hypertensive donors with renal artery stenosis due to atherosclerosis and fibromuscular dysplasia is still debated. The prime concern is about the deleterious effect of hypertension on the donor and the risk of recurrence of such lesions in the solitary kidney. Even as the response of atherosclerotic renal artery stenosis to revascularisation is unpredictable, there is an improvement in blood pressure following revascularisation of kidneys with fibro-muscular dysplasia. The first use of such kidney donors was reported in 1984 and, since then, there have been a few reports of successful use of kidneys from donors with renal artery stenosis. We report here two interesting cases of successful transplantation of kidneys from live related kidney donors with hypertension due to renal artery stenosis who became normotensive with good graft function in the recipient. We conclude that moderately hypertensive donors with renal artery stenosis are fit to donate.
authors.affiliation: Department of Surgical Disciplines, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Vemuru Sunil K
authors.initials: VS
authors.lastname: Reddy
authors.forename: Sandeep
authors.initials: S
authors.lastname: Guleria
authors.forename: Girdhar S
authors.initials: GS
authors.lastname: Bora
mesh_terms: D000368:Aged; D015901:Angiography, Digital Subtraction; D000959:Antihypertensive Agents / Q000627:therapeutic use; D046148:Donor Selection; D005260:Female; D006801:Humans; D006978:Hypertension, Renovascular / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology; D016030:Kidney Transplantation; D019520:Living Donors; D008875:Middle Aged; D009392:Nephrectomy; D011237:Predictive Value of Tests; D012078:Renal Artery Obstruction / Q000150:complications / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000188:drug therapy; D016896:Treatment Outcome
chemical_list: D000959:Antihypertensive Agents