title: Use of conjoint analysis to assess HIV vaccine acceptability: feasibility of an innovation in the assessment of consumer health-care preferences.
abstract: Engaging consumers in prospectively shaping strategies for dissemination of health-care innovations may help to ensure acceptability. We examined the feasibility of using conjoint analysis to assess future HIV vaccine acceptability among three diverse communities: a multiethnic sample in Los Angeles, CA, USA (n = 143); a Thai resident sample in Los Angeles (three groups; n = 27) and an Aboriginal peoples sample in Toronto (n = 13). Efficacy had the greatest impact on acceptability for all three groups, followed by cross-clade protection, side-effects and duration of protection in the Los Angeles sample; side-effects and duration of protection in the Thai-Los Angeles sample; and number of doses and duration of protection in the Aboriginal peoples-Toronto sample. Conjoint analysis provided insights into universal and population-specific preferences among diverse end users of future HIV vaccines, with implications for evidence-informed targeting of dissemination efforts to optimize vaccine uptake.
authors.affiliation: University of California Los Angeles, Department of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior, Center for Community Health, Los Angeles, CA, USA. sjlee@mednet.ucla.edu
authors.forename: S J
authors.initials: SJ
authors.lastname: Lee
authors.forename: P A
authors.initials: PA
authors.lastname: Newman
authors.forename: W S
authors.initials: WS
authors.lastname: Comulada
authors.forename: W E
authors.initials: WE
authors.lastname: Cunningham
authors.forename: N
authors.initials: N
authors.lastname: Duan
mesh_terms: D016915:AIDS Vaccines / Q000008:administration & dosage* / Q000276:immunology; D000293:Adolescent; D000328:Adult; D002170:Canada; D005006:Ethnicity; D015658:HIV Infections / Q000517:prevention & control*; D006801:Humans; D015141:Los Angeles; D008297:Male; D010342:Patient Acceptance of Health Care / Q000706:statistics & numerical data*; D013223:Statistics as Topic; D055815:Young Adult
chemical_list: D016915:AIDS Vaccines