title: A novel I293MP mutation within BCR-ABL kinase domain in a Ph-positive acute lymphoblastic leukemia patient presenting resistant to imatinib but sensitive to nilotinib.
authors.forename: Pu
authors.initials: P
authors.lastname: Kuang
authors.forename: Ting
authors.initials: T
authors.lastname: Liu
authors.forename: Qi
authors.initials: Q
authors.lastname: Huang
authors.forename: Yuanxin
authors.initials: Y
authors.lastname: Ye
authors.forename: Bing
authors.initials: B
authors.lastname: Xiang
authors.forename: Jie
authors.initials: J
authors.lastname: Huang
authors.forename: Lei
authors.initials: L
authors.lastname: Diwu
authors.forename: Yuchun
authors.initials: Y
authors.lastname: Wang
authors.forename: Wentong
authors.initials: W
authors.lastname: Meng
authors.forename: Tian
authors.initials: T
authors.lastname: Dong
authors.forename: Shengyong
authors.initials: S
authors.lastname: Yang
authors.forename: Xiaojun
authors.initials: X
authors.lastname: Lu
mesh_terms: D000328:Adult; D019943:Amino Acid Substitution / Q000235:genetics; D000970:Antineoplastic Agents / Q000494:pharmacology / Q000627:therapeutic use; D001483:Base Sequence; D001549:Benzamides; D018389:Codon, Nonsense / Q000235:genetics / Q000502:physiology; D019008:Drug Resistance, Neoplasm / Q000187:drug effects / Q000235:genetics; D016044:Fusion Proteins, bcr-abl / Q000737:chemistry / Q000235:genetics*; D006801:Humans; D000068877:Imatinib Mesylate; D007532:Isoleucine / Q000235:genetics; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000188:drug therapy* / Q000235:genetics*; D008297:Male; D008958:Models, Molecular; D010770:Phosphotransferases / Q000737:chemistry / Q000235:genetics; D010879:Piperazines / Q000627:therapeutic use; D017434:Protein Structure, Tertiary / Q000235:genetics; D011743:Pyrimidines / Q000494:pharmacology / Q000627:therapeutic use*
chemical_list: D000970:Antineoplastic Agents; D001549:Benzamides; D018389:Codon, Nonsense; D010879:Piperazines; D011743:Pyrimidines; D007532:Isoleucine; D000068877:Imatinib Mesylate; D010770:Phosphotransferases; D016044:Fusion Proteins, bcr-abl; C498826:nilotinib