title: Effects of mesenchymal stem cells isolated from amniotic fluid and platelet-rich plasma gel on severe decubitus ulcers in a septic neonatal foal.
abstract: This paper documents the treatment of severe decubitus ulcers with amniotic fluid mesenchymal stem cells and platelets rich plasma (PRP) gel in a septic neonatal foal. The colt needed 25 days of hospitalization: during this period ulcers were treated for 15 days with mesenchymal stem cells (MSCs) plus PRP, PRP gel alone, or aloe gel. Healing was faster using MSCs+PRP, and at 7 months an ulcer treated with aloe gel was still not completely healed.
authors.affiliation: Department of Veterinary Medical Sciences, Faculty of Veterinary Medicine, University of Bologna, Via Tolara di Sopra 50, 40064 Ozzano dell'Emilia, Bologna, Italy. eleonora.iacono2@unibo.it
authors.forename: E
authors.initials: E
authors.lastname: Iacono
authors.forename: B
authors.initials: B
authors.lastname: Merlo
authors.forename: A
authors.initials: A
authors.lastname: Pirrone
authors.forename: C
authors.initials: C
authors.lastname: Antonelli
authors.forename: L
authors.initials: L
authors.lastname: Brunori
authors.forename: N
authors.initials: N
authors.lastname: Romagnoli
authors.forename: C
authors.initials: C
authors.lastname: Castagnetti
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D005782:Gels; D006734:Horse Diseases / Q000628:therapy*; D006736:Horses; D008297:Male; D045164:Mesenchymal Stem Cell Transplantation / Q000662:veterinary*; D053657:Platelet-Rich Plasma; D003668:Pressure Ulcer / Q000150:complications / Q000628:therapy / Q000662:veterinary*; D018805:Sepsis / Q000150:complications / Q000662:veterinary*; D013997:Time Factors; D014945:Wound Healing / Q000187:drug effects
chemical_list: D005782:Gels