title: Influence of inguinal hernia mesh repair on testicular flow and sperm autoimmunity.
abstract: BACKGROUND
  The incidence of infertility caused by the mesh inguinal hernia repair is not known. The aim of this study was to determine circulation and immunological testicular disorders after inguinal hernia mesh repair which can be related with infertility.
  
  
  METHODS
  From February 2010 to December 2010, 43 male patients who underwent inguinal hernia mesh repair were included in a prospective study. Testicular, capsular and intratesticular arterial flow dynamics were measured by Color Doppler ultrasound before the operation, in early and late postoperative period. The antisperm antibodies were analyzed before hernia repair and 5 months after.
  
  
  RESULTS
  The difference between patients who underwent laparoscopic (Group I) and anterior open tension-free hernia repair (Group II) in age, duration of symptoms and hernia characteristics were not significant. Statistically significant differences were found in peak-systolic and end-diastolic velocity in testicular and intratesticular arteries in Group II and in peak-systolic velocity on all levels in Group I. Only Group I had significant differences in resistive index of intratesticular arteries. All the values returned to basal in late postoperative period except testicular peak-systolic velocity in Group I which stayed in normal range. Wilcox matched pair test showed significant difference between preoperative and late postoperative measurements of the antisperm antibodies only in Group II, but it was within normal range in all cases.
  
  
  CONCLUSIONS
  Inguinal hernia mesh repair do not have clinically significant influence on testicular flow and immunological response.
authors.affiliation: Department of Diagnostic and Interventional Radiology, University Hospital Split, Split University School of Medicine, Split, Croatia.
authors.forename: I
authors.initials: I
authors.lastname: Stula
authors.forename: N
authors.initials: N
authors.lastname: Družijanić
authors.forename: D
authors.initials: D
authors.lastname: Sršen
authors.forename: V
authors.initials: V
authors.lastname: Capkun
authors.forename: Z
authors.initials: Z
authors.lastname: Perko
authors.forename: A
authors.initials: A
authors.lastname: Sapunar
authors.forename: D
authors.initials: D
authors.lastname: Kraljević
authors.forename: N
authors.initials: N
authors.lastname: Bošnjak
authors.forename: Z
authors.initials: Z
authors.lastname: Pogorelić
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000906:Antibodies; D015551:Autoimmunity; D006552:Hernia, Inguinal / Q000601:surgery*; D059685:Herniorrhaphy / Q000009:adverse effects*; D006801:Humans; D007248:Infertility, Male / Q000209:etiology* / Q000276:immunology; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D019919:Prosthesis Implantation; D013094:Spermatozoa / Q000276:immunology*; D013526:Surgical Mesh; D013733:Testicular Diseases / Q000276:immunology*; D013737:Testis / Q000098:blood supply* / Q000000981:diagnostic imaging; D018615:Ultrasonography, Doppler, Color; D055815:Young Adult
chemical_list: D000906:Antibodies