title: Asymmetric pericyclic cascade approach to spirocyclic oxindoles.
abstract: The reaction of chiral N-arylnitrones with carbocyclic alkylarylketenes generates spirocyclic oxindoles in good yields and with excellent levels of enantioselectivity (90-99% ee) via a pericyclic cascade process.
authors.affiliation: EaStCHEM, School of Chemistry, University of St. Andrews, North Haugh, St. Andrews, KY16 9ST, UK.
authors.forename: Edward
authors.initials: E
authors.lastname: Richmond
authors.forename: Nicolas
authors.initials: N
authors.lastname: Duguet
authors.forename: Alexandra M Z
authors.initials: AM
authors.lastname: Slawin
authors.forename: Tomáš
authors.initials: T
authors.lastname: Lébl
authors.forename: Andrew D
authors.initials: AD
authors.lastname: Smith
mesh_terms: D002384:Catalysis; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D000078183:Oxindoles; D013141:Spiro Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism; D013450:Sulfones / Q000138:chemical synthesis*
chemical_list: D007211:Indoles; D000078183:Oxindoles; D013141:Spiro Compounds; D013450:Sulfones; C022960:2-oxindole; C016801:2,4,6-triisopropylbenzenesulfonyl chloride