title: Refractory pyoderma gangrenosum of the orbit and the lacrimal sac.
abstract: Pyoderma gangrenosum (PG) is a rare, idiopathic, necrotizing, and non-infectious ulcerating skin disease included among the neutrophilic dermatoses. It rarely affects the eye, orbit, and/or ocular adnexa. We describe one case of PG affecting both orbits and the lacrimal sac in a patient with Crohn's disease.
authors.affiliation: Department of Ophthalmology, Hospital Universitario de León, León, Spain. miguelcorderocoma@gmail.com
authors.forename: Miguel
authors.initials: M
authors.lastname: Cordero-Coma
authors.forename: José V
authors.initials: JV
authors.lastname: Pérez-Moreiras
authors.forename: Alvaro
authors.initials: A
authors.lastname: Toribio
authors.forename: Nieves
authors.initials: N
authors.lastname: Alonso-Orcajo
authors.forename: Sara
authors.initials: S
authors.lastname: Calleja
authors.forename: Manuel
authors.initials: M
authors.lastname: Franco
authors.forename: José G
authors.initials: JG
authors.lastname: Ruiz de Morales
mesh_terms: D000284:Administration, Oral; D000328:Adult; D003424:Crohn Disease / Q000150:complications; D003520:Cyclophosphamide / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007766:Lacrimal Apparatus Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D008279:Magnetic Resonance Imaging; D008775:Methylprednisolone / Q000627:therapeutic use; D009916:Orbital Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D011241:Prednisone / Q000627:therapeutic use; D020551:Pulse Therapy, Drug; D017511:Pyoderma Gangrenosum / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D014792:Visual Acuity
chemical_list: D005938:Glucocorticoids; D007166:Immunosuppressive Agents; D003520:Cyclophosphamide; D011241:Prednisone; D008775:Methylprednisolone