title: Convergent synthesis of the pentasaccharide repeating unit of the O-antigenic polysaccharide of enterohaemorrhagic Escherichia coli O113.
abstract: An acidic pentasaccharide repeating unit corresponding to the O-antigenic polysaccharide of enterohaemorrhagic Escherichia coli O113 as its p-methoxyphenyl glycoside has been synthesized in a convergent manner by adopting a [3+2] block glycosylation strategy. During the synthetic endeavor a one-pot reaction condition for stereoselective glycosylation and protecting group manipulation has been applied. All glycosylation steps are highly stereoselective with good to excellent yield.
authors.affiliation: Division of Molecular Medicine, Bose Institute, P-1/12, C.I.T. Scheme VII M, Kolkata, 700054, India.
authors.forename: Abhishek
authors.initials: A
authors.lastname: Santra
authors.forename: Anup Kumar
authors.initials: AK
authors.lastname: Misra
mesh_terms: D002240:Carbohydrate Sequence; D054324:Enterohemorrhagic Escherichia coli / Q000378:metabolism*; D006031:Glycosylation; D008969:Molecular Sequence Data; D019081:O Antigens / Q000737:chemistry*; D011134:Polysaccharides / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D019081:O Antigens; D011134:Polysaccharides