title: [Rapid course of Churge-Strauss syndrome--since appearance of asthma till development of renal failure and neurological complication].
abstract: Churge-Strauss Syndrome belongs to systematic, necrotic inflammation of medium and small vessels diseases. In this paper it is presented a case of 63 years old man with benign asthma, recognized six month earlier. Later occurs fever, difficulties with breathing, cough, fast progressing paresis of tree limbs, thinning and nephrotic syndrome with fast growing renal failure. Base for recognition was clinical picture and laboratory tests which showed elevetion of inflammation parameters (CRP, ESR), eosinophilia (18%) and p-ANCA antibodies. Treatment with glucocorticosteroids and cyclophosphamide was started. After six month proteinuria decreased. Paresis regressed and patient's movement abilities were improved. Renal failure stayed in fourth stadium of chronic renal disease. The aim of this paper is presentation diagnostic difficulties of Churge-Strauss Syndrome of atypical course with fast growing renal failure with neurological complications.
authors.affiliation: Wojskowy Instytut Medyczny w Warszawie, Klinika Chorób Wewnetrznych, Nefrologii i Dializoterapii CSK MON. idubchak@wim.mil.pl
authors.forename: Ivanna
authors.initials: I
authors.lastname: Dubchak
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Gomółka
authors.forename: Stanisław
authors.initials: S
authors.lastname: Niemczyk
mesh_terms: D001249:Asthma / Q000150:complications* / Q000175:diagnosis; D015267:Churg-Strauss Syndrome / Q000175:diagnosis* / Q000209:etiology* / Q000628:therapy; D003937:Diagnosis, Differential; D018450:Disease Progression; D006801:Humans; D008297:Male; D008875:Middle Aged; D009422:Nervous System Diseases / Q000175:diagnosis; D051437:Renal Insufficiency / Q000175:diagnosis / Q000209:etiology*