title: Nationwide survey on the 2005 Guidelines for the Management of Community-Acquired Adult Pneumonia: validation of severity assessment.
abstract: BACKGROUND
  The Japanese Respiratory Society Guidelines for the Management of Community-Acquired Pneumonia (CAP) in Adults (JRS 2005) were published to revise the Basic Concept for the Management of CAP in Adults (JRS 2000). Revisions in JRS 2005 mainly focused on the criteria for the assessment of pneumonia severity and the differentiation between bacterial pneumonia and atypical pneumonia. To evaluate the JRS 2005 criteria for the assessment of pneumonia severity, we conducted a prospective survey.
  
  
  METHODS
  The survey was conducted from July 2006 to March 2007 as a nationwide joint study by 200 institutions. The study subjects included patients aged ≥16 years of age who had CAP. The severity at initial consultation was determined using the criteria established by JRS 2005, JRS 2000, and Infectious Diseases Society of America Guidelines (IDSA-GLs). The survival outcome 30 days after the start of the initial antimicrobial agent treatment was confirmed.
  
  
  RESULTS
  A total of 1875 patients were analyzed. The numbers of cases of pneumonia assessed as being moderate and severe were significantly lower when the JRS 2005 criteria were used than when the JRS 2000 criteria were used. Thus, the severity of pneumonia could be determined more appropriately using the JRS 2005 criteria. Furthermore, the severity-dependent prediction of fatal outcomes or mortality according to these criteria was similar to that determined using the IDSA-GLs.
  
  
  CONCLUSIONS
  Determining severity on the basis of JRS 2005 can resolve nearly all the problems encountered with JRS 2000; these criteria were found to be useful and rapidly and easily applicable in clinical practice.
authors.affiliation: Institute of Development, Aging and Cancer, Tohoku University, Research Division for Development of Anti-Infective Agents, Seiryo-machi 4-1, Aoba-ku, Sendai 980-8575, Miyagi, Japan. akiwa@idac.tohoku.ac.jp
authors.forename: Akira
authors.initials: A
authors.lastname: Watanabe
authors.forename: Hajime
authors.initials: H
authors.lastname: Goto
authors.forename: Shigeru
authors.initials: S
authors.lastname: Kohno
authors.forename: Toshiharu
authors.initials: T
authors.lastname: Matsushima
authors.forename: Shosaku
authors.initials: S
authors.lastname: Abe
authors.forename: Nobuki
authors.initials: N
authors.lastname: Aoki
authors.forename: Kaoru
authors.initials: K
authors.lastname: Shimokata
authors.forename: Keiichi
authors.initials: K
authors.lastname: Mikasa
authors.forename: Yoshihito
authors.initials: Y
authors.lastname: Niki
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D017714:Community-Acquired Infections; D003937:Diagnosis, Differential; D006801:Humans; D007564:Japan; D008875:Middle Aged; D018410:Pneumonia, Bacterial / Q000175:diagnosis* / Q000188:drug therapy / Q000401:mortality; D017410:Practice Guidelines as Topic; D011379:Prognosis; D011446:Prospective Studies; D015272:Pulmonary Medicine / Q000458:organization & administration; D012720:Severity of Illness Index; D012955:Societies, Medical / Q000458:organization & administration; D015996:Survival Rate; D013997:Time Factors; D014481:United States; D055815:Young Adult
chemical_list: D000900:Anti-Bacterial Agents