title: Improvement of accommodation with anti-oxidant supplementation in visual display terminal users.
abstract: OBJECTIVE
  To determine the antioxidant supplementation effect on accommodation among VDT users.
  
  
  METHODS
  A double blind randomized placebo controlled study. Registered under ClinicalTrials.gov Identifier No. NCT00877201.
  
  
  METHODS
  Fourty right eyes of 40 healthy VDT users (30 females, 10 males, mean age: 43.8±2.8 years, range: 40-49 years). 20 subjects (15 females, 5 males; mean age: 44.0±2.7 years, range: 40-49 years).
  
  
  METHODS
  Subjects were required to take an antioxidant supplement, 20 age and sex matched subjects (15 females, 5 males; mean age: 43.6±3.1 years, range: 40-49 years) were required to take placebo medication for 4 weeks.
  
  
  RESULTS
  The mean of the change in accommodation power was significantly higher in the group receiving antioxidant supplements (0.20±0.50 Diopter(D)) compared to the placebo group (-0.12±0.48(D)) (p<0.05).
  
  
  CONCLUSIONS
  Antioxidant supplementation was observed to improve accommodation in Japanese Visual Display Terminal (VDT) Users.
authors.affiliation: Department of Ophthalmology, Keio University school of Medicine, Tokyo, Japan. hmpgx653@ybb.ne.jp
authors.forename: Y
authors.initials: Y
authors.lastname: Uchino
authors.forename: M
authors.initials: M
authors.lastname: Uchino
authors.forename: M
authors.initials: M
authors.lastname: Dogru
authors.forename: K
authors.initials: K
authors.lastname: Fukagawa
authors.forename: K
authors.initials: K
authors.lastname: Tsubota
mesh_terms: D000065:Accommodation, Ocular / Q000187:drug effects*; D000328:Adult; D000975:Antioxidants / Q000627:therapeutic use*; D016288:Computer Terminals; D019587:Dietary Supplements; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007564:Japan; D008297:Male; D008875:Middle Aged
chemical_list: D000975:Antioxidants