title: Mechanisms and models of the active transport of ions and the transformation of energy in intracellular compartments.
abstract: Various transport models and mechanisms for ions from different compartments of the cell are considered. Compartments such as mitochondria, synaptic vesicles, sarco- and endoplasmic reticulum and vacuoles are considered. It is shown that an adequate description of the compartment-based substance transport can be developed using thermodynamically correct models. Such models are used to calculate both the concentrations of ions in such compartments and the resting potential on their membranes. The problem of the complexity of transport systems is also discussed.
authors.affiliation: Ural Federal University, Mira Str 19, 620002 Yekaterinburg, Russia. melkikh2008@rambler.ru
authors.forename: Alexey V
authors.initials: AV
authors.lastname: Melkikh
authors.forename: Vladimir D
authors.initials: VD
authors.lastname: Seleznev
mesh_terms: D001693:Biological Transport, Active; D002451:Cell Compartmentation / Q000502:physiology*; D003198:Computer Simulation; D004734:Energy Metabolism; D007425:Intracellular Membranes / Q000502:physiology; D007477:Ions / Q000378:metabolism*; D007700:Kinetics; D008564:Membrane Potentials; D008954:Models, Biological; D013816:Thermodynamics
chemical_list: D007477:Ions