title: Two new steroidal saponins from the biotransformation product of the rhizomes of Dioscorea nipponica.
abstract: Two new steroidal saponins, dioscins E (1) and F (2), along with nine known steroidal saponins, were isolated from the biotransformation product of the rhizomes of Dioscorea nipponica using Aspergillus oryzae. The structures of new compounds were established as 25(R)-spirost-5-en-21β-methyl-3β-ol-3-O-α-L-rhamnopyranosyl-(1 → 4)-β-D-glucopyranoside (1) and (25R)-spirost-5-en-3β-ol-7-one 3-O-α-L-rhamnopyranosyl-(1 → 4)-β-D-glucopyranoside (2) by detailed spectroscopic analyses including 1D and 2D NMR spectral data ((1)H-(1)H COSY, HSQC, and HMBC) and MS spectrometry.
authors.affiliation: Liaoning University of Traditional Chinese Medicine, Liaoning, 110032, China.
authors.forename: Li-Juan
authors.initials: LJ
authors.lastname: Zhang
authors.forename: He-Shui
authors.initials: HS
authors.lastname: Yu
authors.forename: Li-Ping
authors.initials: LP
authors.lastname: Kang
authors.forename: Bing
authors.initials: B
authors.lastname: Feng
authors.forename: Bo
authors.initials: B
authors.lastname: Quan
authors.forename: Xin-Bo
authors.initials: XB
authors.lastname: Song
authors.forename: Bai-Ping
authors.initials: BP
authors.lastname: Ma
authors.forename: Ting-Guo
authors.initials: TG
authors.lastname: Kang
mesh_terms: D001236:Aspergillus oryzae / Q000378:metabolism; D001711:Biotransformation; D027742:Dioscorea / Q000737:chemistry*; D004144:Diosgenin / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D027343:Rhizome / Q000737:chemistry; D012503:Saponins / Q000737:chemistry / Q000302:isolation & purification*; D013237:Stereoisomerism
chemical_list: D012503:Saponins; D004144:Diosgenin