title: Prevalence of glucose-6-phosphate dehydrogenase deficiency among neonates at a tertiary care centre in Lebanon.
abstract: In this study we aimed to determine the prevalence of glucose-6-phosphate dehydrogenase (G6PD) deficiency in a Lebanese population and the clinical outcomes and associated adverse events encountered amongst affected patients. Newborn screening in a tertiary care centre in North Lebanon showed a prevalence of 2.1% (62 out of 3009), significantly higher in males than females, and in Muslims than Christians. Among 45 infants followed for a median of 2.2 years from birth, 12 (27%) were admitted to hospital for severe haemolytic crises, despite a programme of early family education and close follow-up. A nationwide newborn screening program to identify afflicted individuals, and to augment vigilance about this disease, should be considered in countries where the disorder is prevalent.
authors.affiliation: Lebanese American University, School of Medicine, Byblos, Lebanon. adlette.inati@lau.edu.lb
authors.forename: Adlette
authors.initials: A
authors.lastname: Inati
authors.forename: Hussein A
authors.initials: HA
authors.lastname: Abbas
authors.forename: Christine
authors.initials: C
authors.lastname: Boumitri
authors.forename: Najib
authors.initials: N
authors.lastname: Tecle
mesh_terms: D005955:Glucosephosphate Dehydrogenase Deficiency / Q000453:epidemiology*; D006801:Humans; D007231:Infant, Newborn; D007861:Lebanon / Q000453:epidemiology; D015997:Neonatal Screening; D015995:Prevalence