title: Discovery of small molecules that bind to K-Ras and inhibit Sos-mediated activation.
authors.affiliation: Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.
authors.forename: Qi
authors.initials: Q
authors.lastname: Sun
authors.forename: Jason P
authors.initials: JP
authors.lastname: Burke
authors.forename: Jason
authors.initials: J
authors.lastname: Phan
authors.forename: Michael C
authors.initials: MC
authors.lastname: Burns
authors.forename: Edward T
authors.initials: ET
authors.lastname: Olejniczak
authors.forename: Alex G
authors.initials: AG
authors.lastname: Waterson
authors.forename: Taekyu
authors.initials: T
authors.lastname: Lee
authors.forename: Olivia W
authors.initials: OW
authors.lastname: Rossanese
authors.forename: Stephen W
authors.initials: SW
authors.lastname: Fesik
mesh_terms: D018360:Crystallography, X-Ray; D011905:Genes, ras / Q000187:drug effects*; D015394:Molecular Structure; D054852:Small Molecule Libraries / Q000737:chemistry* / Q000494:pharmacology; D020664:Son of Sevenless Proteins / Q000037:antagonists & inhibitors*
chemical_list: D054852:Small Molecule Libraries; D020664:Son of Sevenless Proteins