title: Light and transmission electron microscopy of generalized dystrophic epidermolysis bullosa (Pasini's albopapuloid subtype).
abstract: Pasini's albopapuloid epidermolysis bullosa is a very rare subtype of generalized dystrophic dominant epidermolyis bullosa. A 30 year-old white female patient presented since her childhood disseminated small blisters and papules. Light microscopy of a blister showed dermal-epidermal cleavage; moreover, focal areas of dermal-epidermal splitting were also observed. Transmission electron microscopy also identified focal areas of cleavage, which were seen below the lamina densa. It is important to recognize this condition as a variant of epidermolysis bullosa, since the most important cutaneous findings are generalized papules and not blisters and erosions as in other forms of epidermolysis bullosa.
authors.affiliation: Universidade Federal de Pelotas, Pelotas, RS, Brazil. hiramalmeidajr@hotmail.com
authors.forename: Hiram Larangeira de
authors.initials: HL
authors.lastname: Almeida
authors.forename: Lísia
authors.initials: L
authors.lastname: Nudelmann
authors.forename: Nara Moreira
authors.initials: NM
authors.lastname: Rocha
authors.forename: Luis Antonio Suita de
authors.initials: LA
authors.lastname: Castro
mesh_terms: D000328:Adult; D016108:Epidermolysis Bullosa Dystrophica / Q000145:classification / Q000473:pathology*; D005260:Female; D006801:Humans; D046529:Microscopy, Electron, Transmission