title: [Biomechanical analysis of bilateral facet joint stabilization for posterior cervical spine reconstruction with bio-derived tendon in goats].
abstract: OBJECTIVE
  There is few report on dynamic stabilization for posterior cervical reconstruction. To investigate the biomechanical properties of a novel cervical spine posterior fixation using the bio-derived freeze-dried tendon in posterior cervical spine reconstruction.
  
  
  METHODS
  The palmaris longus flexor tendon and metacarpal extensor tendon were collected from the death donors' stump to prepare bio-derived tendon. Twenty fresh cervical vertebrae (C1-7) were harvested from goats and were randomly divided into 4 groups (n = 5): intact group (group A); injury control group (group B); screw-rods fixation group, fixed with screw-rods on C3, 4 (group C); tendon reconstruction group, cross-fixed with bio-derived freeze-dried tendon on C3, 4 bilatera facet joints (group D). The range of motion (ROM) values in flexion, extension, lateral bending, and axial rotation were measured.
  
  
  RESULTS
  In flexion, the ROM values of group C were significantly lower than those of the other 3 groups (P < 0.05), and the ROM values of group B were significantly higher than those of groups A and D (P < 0.05). In extension, lateral bending, and axial rotation, the ROM values of group C were significantly lower than those of groups A, B, and D (P < 0.05), and no significant difference was found within the other 3 groups (P > 0.05).
  
  
  CONCLUSIONS
  The novel cervical spine posterior fixation using the bio-derived frozen-dried tendon can provide enough stability in flexion motion, but it can not limit the lateral bending and axial rotation motion, which can provide dynamic stabilization in animal model.
authors.affiliation: Department of Orthopedics, State Key Laboratory of Biotherapy, West China Hospital of Sichuan University, Chengdu Sichuan, 610041, P.R. China.
authors.forename: Beiyu
authors.initials: B
authors.lastname: Wang
authors.forename: Hao
authors.initials: H
authors.lastname: Liu
authors.forename: Weiguang
authors.initials: W
authors.lastname: Hou
authors.forename: Huiqi
authors.initials: H
authors.lastname: Xie
authors.forename: Yueming
authors.initials: Y
authors.lastname: Song
authors.forename: Ying
authors.initials: Y
authors.lastname: Hong
authors.forename: Rui
authors.initials: R
authors.lastname: Shi
authors.forename: Litai
authors.initials: L
authors.lastname: Ma
mesh_terms: D000818:Animals; D001672:Biocompatible Materials; D001696:Biomechanical Phenomena; D002102:Cadaver; D002574:Cervical Vertebrae / Q000293:injuries* / Q000601:surgery*; D004195:Disease Models, Animal; D005260:Female; D006041:Goats; D006801:Humans; D016268:Internal Fixators; D007593:Joint Instability / Q000601:surgery; D008022:Ligaments / Q000293:injuries / Q000601:surgery; D008297:Male; D016059:Range of Motion, Articular / Q000502:physiology; D013123:Spinal Fusion / Q000295:instrumentation / Q000379:methods*; D013710:Tendons / Q000637:transplantation*; D021801:Zygapophyseal Joint / Q000601:surgery
chemical_list: D001672:Biocompatible Materials