title: Cleidbrevoids A-C, new clerodane diterpenoids from Cleidion brevipetiolatum.
abstract: Three new clerodane-type diterpenoids with a rare sulfoxide group, cleidbrevoids A-C (1-3), were isolated from the twigs and leaves of Cleidion brevipetiolatum. Their structures were elucidated on the basis of spectroscopic methods and the absolute configuration of compounds 1 and 3 was determined by X-ray analysis. Compound 3 showed weak inhibitory against HIV-1.
authors.affiliation: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, People's Republic of China.
authors.forename: Yuan-Yuan
authors.initials: YY
authors.lastname: Cheng
authors.forename: Shi-Fei
authors.initials: SF
authors.lastname: Li
authors.forename: Yu
authors.initials: Y
authors.lastname: Zhang
authors.forename: Gui-Hua
authors.initials: GH
authors.lastname: Tang
authors.forename: Ying-Tong
authors.initials: YT
authors.lastname: Di
authors.forename: Xiao-Jiang
authors.initials: XJ
authors.lastname: Hao
authors.forename: Shun-Lin
authors.initials: SL
authors.lastname: Li
authors.forename: Hong-Ping
authors.initials: HP
authors.lastname: He
mesh_terms: D000998:Antiviral Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D045785:Diterpenes, Clerodane / Q000737:chemistry* / Q000302:isolation & purification* / Q000494:pharmacology; D015497:HIV-1 / Q000187:drug effects*; D015394:Molecular Structure; D010936:Plant Extracts / Q000737:chemistry* / Q000494:pharmacology; D018515:Plant Leaves / Q000737:chemistry; D018547:Plant Stems / Q000737:chemistry
chemical_list: D000998:Antiviral Agents; D045785:Diterpenes, Clerodane; D010936:Plant Extracts; C576437:cleidbrevoid A; C576439:cleidbrevoid B; C576438:cleidbrevoid C