title: Arterial thromboembolism in senile systemic amyloidosis: report of two cases.
abstract: We describe a rare complication, systemic arterial thromboembolism, seen in two patients with senile systemic amyloidosis (SSA). Case 1 was a 73-year-old man who was tentatively diagnosed as having cardiac amyloidosis. Five months later, he was afflicted by severe left flank pain. CT disclosed renal infarction and then he received endomyocardial biopsy and the transthyretin (TTR) gene analysis, leading to the final diagnosis of SSA. Case 2 was an 88-year-old woman who had been definitively diagnosed as having SSA-related heart failure with atrial fibrillation two years before. She was transferred to the emergency room in our hospital and enhanced CT revealed complete occlusions of the left internal carotid and left vertebral arteries, both subclavian arteries, and the left renal and left internal iliac arteries. Paying much attention to intracardiac thrombosis might be necessary in taking care of SSA patients.
authors.affiliation: Department of Medicine, Shinshu University School of Medicine, Matsumoto, Japan.
authors.forename: Michitaka
authors.initials: M
authors.lastname: Nakagawa
authors.forename: Kana
authors.initials: K
authors.lastname: Tojo
authors.forename: Yoshiki
authors.initials: Y
authors.lastname: Sekijima
authors.forename: Kyo-hei
authors.initials: KH
authors.lastname: Yamazaki
authors.forename: Shu-ichi
authors.initials: S
authors.lastname: Ikeda
mesh_terms: D050153:Abdominal Fat / Q000473:pathology; D000368:Aged; D000369:Aged, 80 and over; D000682:Amyloid / Q000378:metabolism; D000686:Amyloidosis / Q000150:complications / Q000175:diagnosis* / Q000378:metabolism; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007668:Kidney / Q000098:blood supply / Q000473:pathology; D018810:Magnetic Resonance Angiography; D008297:Male; D009206:Myocardium / Q000473:pathology; D011228:Prealbumin / Q000378:metabolism; D013923:Thromboembolism / Q000175:diagnosis* / Q000209:etiology / Q000378:metabolism
chemical_list: D000682:Amyloid; D011228:Prealbumin; C076571:transthyretin-related amyloid fibril protein, human