title: Systemic lupus erythematosus in children and adolescents.
abstract: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with a wide range of disease manifestations that can involve any organ system, and can lead to significant morbidity and even mortality. This article reviews the epidemiology, common clinical features, and complications of the disease, and briefly discusses the available treatment options. In addition, important medical and psychosocial issues relevant to the pediatrician caring for children and adolescents with SLE are discussed.
authors.affiliation: Division of Rheumatology, Hospital for Sick Children, University of Toronto, 555 University Avenue, Toronto, ON M5G 1X8, Canada. deborah.levy@sickkids.ca
authors.forename: Deborah M
authors.initials: DM
authors.lastname: Levy
authors.forename: Sylvia
authors.initials: S
authors.lastname: Kamphuis
mesh_terms: D000293:Adolescent; D002648:Child; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008180:Lupus Erythematosus, Systemic / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology; D016896:Treatment Outcome
chemical_list: D007166:Immunosuppressive Agents