title: DNA microarray expression analysis of baicalin-induced differentiation of C17.2 neural stem cells.
abstract: Identifying baicalin-regulated genes for neuronal differentiation: Baicalin is a potent neuronal-differentiation-inducing compound. This study explored the gene expression regulated through baicalin-induced differentiation of C17.2 neural stem cells by using a DNA microarray followed by qPCR validation. The expression of 15 genes was significantly regulated among the 58 differentially expressed genes important for nervous system development and function.
authors.affiliation: State Key Laboratory of Phytochemistry and Plant Resources in West China (CUHK), Institute of Chinese Medicine, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, P. R. China.
authors.forename: Ming
authors.initials: M
authors.lastname: Li
authors.forename: Sze-Ting
authors.initials: ST
authors.lastname: Choi
authors.forename: Kam-Sze
authors.initials: KS
authors.lastname: Tsang
authors.forename: Pang-Chui
authors.initials: PC
authors.lastname: Shaw
authors.forename: Kwok-Fai
authors.initials: KF
authors.lastname: Lau
mesh_terms: D000818:Animals; D002454:Cell Differentiation / Q000187:drug effects* / Q000235:genetics*; D002460:Cell Line; D005419:Flavonoids / Q000494:pharmacology*; D020869:Gene Expression Profiling; D051379:Mice; D058953:Neural Stem Cells / Q000166:cytology* / Q000187:drug effects / Q000378:metabolism; D020411:Oligonucleotide Array Sequence Analysis
chemical_list: D005419:Flavonoids; C038044:baicalin