title: Two new cyanogenic glucosides from the leaves of Hydrangea macrophylla.
abstract: Chemical investigation of the ethanol extract of the aerial parts of Hydrangea macrophylla collected in the Sichuan Province of China resulted in the isolation of two new cyanogenic glucosides. Their structures were elucidated as [(2R)-2-β-D-glucopyranosyloxy)-2-(3,4-dimethoxy-phenyl)] acetonitrile (1) and {(2R)-2-[α-D-glucopyranosyl(1-->6)β-D-glucopyranosyloxy]-2-(3-hydroxy-4-methoxy-phenyl)}acetonitrile (2) on the basis of extensive spectroscopic analysis (1D, 2D NMR and HRESIMS) and chemical studies.
authors.affiliation: College of Pharmacy, Harbin Medical University, No. 157 Baojian Road, Nangang District, Harbin 150081, China.
authors.forename: Chun-Juan
authors.initials: CJ
authors.lastname: Yang
authors.forename: Zhi-Bin
authors.initials: ZB
authors.lastname: Wang
authors.forename: Da-Ling
authors.initials: DL
authors.lastname: Zhu
authors.forename: Ying
authors.initials: Y
authors.lastname: Yu
authors.forename: Yin-Ting
authors.initials: YT
authors.lastname: Lei
authors.forename: Yan
authors.initials: Y
authors.lastname: Liu
mesh_terms: D005960:Glucosides / Q000302:isolation & purification*; D006027:Glycosides / Q000302:isolation & purification*; D031966:Hydrangea / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D035261:Plant Components, Aerial / Q000737:chemistry*; D018515:Plant Leaves / Q000737:chemistry*
chemical_list: D005960:Glucosides; D006027:Glycosides; C007173:cyanogenic glycosides