title: Efficient synthesis of γ-keto sulfones by NHC-catalyzed intermolecular Stetter reaction.
abstract: The N-heterocyclic carbene-catalyzed intermolecular Stetter reaction of aldehydes with α,β-unsaturated sulfones allows the atom-economic and selective formation of γ-keto sulfones in good yields. Key to the success of this unique transition-metal-free carbon-carbon bond-forming reaction is the right choice of the NHC precursor and base. The reaction tolerates a broad range of different aldehydes.
authors.affiliation: Organic Chemistry Division, CSIR-National Chemical Laboratory, Dr. Homi Bhabha Road, Pune-411008, India.
authors.forename: Anup
authors.initials: A
authors.lastname: Bhunia
authors.forename: Santhivardhana Reddy
authors.initials: SR
authors.lastname: Yetra
authors.forename: Sachin Suresh
authors.initials: SS
authors.lastname: Bhojgude
authors.forename: Akkattu T
authors.initials: AT
authors.lastname: Biju