title: Biochemical and hematological evaluations of bryonia epigaea tubers.
abstract: Bryonia epigaea (cucurbitaceae) has been evaluated on various inflammatory models in rats in our laboratory. Ana anti-inflammatory drug(s) irrespective of its potency may not be devoid of undesirable effects on biochemical and hematological parameters. Alcoholic extract of Bryonia epigaaea (BE-Extract) at the dose of 50 mg/kg body weight, was administered to rats. Hepatotxic and nephrotoxic effects of BE-Extract were studies by measuring cholesterol, urea, uric acid, SGOT, SGPT and glucose levels in blood. Effects of BE-Extract on RBC count, WBC count, platelet count, hemoglobin content, clotting and bleeding time were also studied.
authors.affiliation: Department of Pharmaceutical Sciences, Birla Institute of Technology, Mesra, Ranchi - 835 215, India.
authors.forename: B N
authors.initials: BN
authors.lastname: Sinha
authors.forename: D
authors.initials: D
authors.lastname: Sasmal
authors.forename: S P
authors.initials: SP
authors.lastname: Basu