title: Imaging of complications of oncological therapy in the gastrointestinal system.
abstract: Treatment of cancer involves a multidisciplinary approach consisting of surgery, chemotherapy, molecular targeted therapy and radiation therapy. These therapies work on the tumor cells to result in cell stasis or cell death. The same mechanism can result in toxicity to the normal gastrointestinal tract. Radiation therapy can cause acute and chronic injury. The chronic injury results from involvement of the vascular supply of the gastrointestinal tract and by causing fibrosis. The purpose of this article is to describe the imaging of complications resulting from oncologic treatment in the gastrointestinal system.
authors.affiliation: Division of Diagnostic Imaging, UT MD Anderson Cancer Center, 1515 Holcombe Boulevard Unit 1473, PO Box, Houston, TX 77030, USA.
authors.forename: Chitra
authors.initials: C
authors.lastname: Viswanathan
authors.forename: Priya
authors.initials: P
authors.lastname: Bhosale
authors.forename: Dhakshin Moorthy
authors.initials: DM
authors.lastname: Ganeshan
authors.forename: Myelene T
authors.initials: MT
authors.lastname: Truong
authors.forename: Paul
authors.initials: P
authors.lastname: Silverman
authors.forename: Aparna
authors.initials: A
authors.lastname: Balachandran
mesh_terms: D020533:Angiogenesis Inhibitors / Q000009:adverse effects / Q000627:therapeutic use; D061067:Antibodies, Monoclonal, Humanized / Q000009:adverse effects / Q000627:therapeutic use; D000970:Antineoplastic Agents / Q000009:adverse effects* / Q000145:classification / Q000627:therapeutic use; D000068258:Bevacizumab; D001808:Blood Vessels / Q000293:injuries / Q000473:pathology / Q000528:radiation effects; D016360:Clostridioides difficile; D004761:Enterocolitis, Pseudomembranous / Q000209:etiology; D005355:Fibrosis; D005759:Gastroenteritis / Q000000981:diagnostic imaging / Q000209:etiology / Q000473:pathology; D005767:Gastrointestinal Diseases / Q000139:chemically induced / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology; D006801:Humans; D045823:Ileus / Q000139:chemically induced / Q000000981:diagnostic imaging; D016867:Immunocompromised Host; D008107:Liver Diseases / Q000000981:diagnostic imaging / Q000209:etiology; D058990:Molecular Targeted Therapy / Q000009:adverse effects*; D009369:Neoplasms / Q000628:therapy*; D009503:Neutropenia / Q000139:chemically induced; D010195:Pancreatitis / Q000139:chemically induced / Q000000981:diagnostic imaging / Q000209:etiology; D011006:Pneumatosis Cystoides Intestinalis / Q000139:chemically induced / Q000000981:diagnostic imaging; D011183:Postoperative Complications / Q000175:diagnosis*; D011832:Radiation Injuries / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology; D011859:Radiography; D011878:Radiotherapy / Q000009:adverse effects*
chemical_list: D020533:Angiogenesis Inhibitors; D061067:Antibodies, Monoclonal, Humanized; D000970:Antineoplastic Agents; D000068258:Bevacizumab