title: Postoperative hematological changes after spleen-preserving distal pancreatectomy with preservation of the splenic artery and vein.
abstract: BACKGROUND
  The aim of this study was to determine the early postoperative hematological changes after spleen-preserving distal pancreatectomy (SpDP) with preservation of the splenic artery and vein (PSAV).
  
  
  METHODS
  We reviewed 53 patients who underwent SpDP with PSAV (n = 21) or distal pancreatectomy with splenectomy (DPS; n = 32) for benign or low-grade malignant lesions between July 1998 and June 2010. Red and white blood cell (WBC) count, platelet count, serum hemoglobin, hematocrit, C-reactive protein, albumin level, and clinical factors were compared between the SpDP with PSAV and DPS.
  
  
  RESULTS
  There were no significant differences in the patient characteristics between the two groups. Platelet count on postoperative day (POD) 5 and WBC count on POD 3 were significantly higher in the DPS group, and these differences continued to be significant until the 3rd month after surgery. Serum hemoglobin and hematocrit in the 1st month after surgery were also significantly higher in the SpDP with PSAV group.
  
  
  CONCLUSIONS
  The hematological benefits of SpDP with PSAV include reduction of postoperative hematological abnormalities in the early postoperative phase and recovery of the serum hemoglobin and hematocrit levels in the early postoperative phase.
authors.affiliation: Department of Gastroenterological, Breast, Thyroid and General Surgery, Yamagata University Faculty of Medicine, Yamagata, Japan.
authors.forename: Koji
authors.initials: K
authors.lastname: Tezuka
authors.forename: Wataru
authors.initials: W
authors.lastname: Kimura
authors.forename: Ichiro
authors.initials: I
authors.lastname: Hirai
authors.forename: Toshiyuki
authors.initials: T
authors.lastname: Moriya
authors.forename: Toshihiro
authors.initials: T
authors.lastname: Watanabe
authors.forename: Mitsuhiro
authors.initials: M
authors.lastname: Yano
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002097:C-Reactive Protein / Q000378:metabolism; D015331:Cohort Studies; D004906:Erythrocyte Count; D005260:Female; D005500:Follow-Up Studies; D006400:Hematocrit; D006402:Hematologic Diseases / Q000209:etiology / Q000517:prevention & control*; D006403:Hematologic Tests; D006454:Hemoglobins; D006801:Humans; D007958:Leukocyte Count; D008297:Male; D008875:Middle Aged; D059351:Organ Sparing Treatments / Q000379:methods*; D010180:Pancreatectomy / Q000009:adverse effects / Q000379:methods*; D010190:Pancreatic Neoplasms / Q000473:pathology / Q000601:surgery*; D010976:Platelet Count; D011184:Postoperative Period; D012189:Retrospective Studies; D013154:Spleen / Q000098:blood supply / Q000601:surgery; D013156:Splenectomy / Q000379:methods; D013157:Splenic Artery; D013162:Splenic Vein; D016896:Treatment Outcome
chemical_list: D006454:Hemoglobins; D002097:C-Reactive Protein