title: Two consecutive open heart operations in a small child with heparin-induced thrombocytopenia type II using anticoagulation with heparin and tirofiban.
abstract: We report the use of the platelet glycoprotein IIb/IIIa antagonist tirofiban for cardiac surgery in a small child with active heparin-induced thrombocytopenia type II, including description of the postoperative course.
authors.affiliation: Institute of Anesthesiology, Department of Pediatric Cardiology, German Heart Center Munich, Munich, Germany. neuray@dhm.mhn.de
authors.forename: Markus
authors.initials: M
authors.lastname: Neuray
authors.forename: Gunter
authors.initials: G
authors.lastname: Balling
authors.forename: Christian
authors.initials: C
authors.lastname: Schreiber
authors.forename: Klaus
authors.initials: K
authors.lastname: Martin
mesh_terms: D000925:Anticoagulants / Q000009:adverse effects* / Q000627:therapeutic use; D049628:Body Size; D006348:Cardiac Surgical Procedures / Q000379:methods; D004359:Drug Therapy, Combination; D006343:Heart Septal Defects / Q000150:complications / Q000601:surgery*; D006493:Heparin / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D007223:Infant; D008297:Male; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use*; D013921:Thrombocytopenia / Q000139:chemically induced* / Q000145:classification; D000077466:Tirofiban; D014443:Tyrosine / Q000031:analogs & derivatives* / Q000627:therapeutic use
chemical_list: D000925:Anticoagulants; D010975:Platelet Aggregation Inhibitors; D014443:Tyrosine; D006493:Heparin; D000077466:Tirofiban