title: [Activation of the sensorimotor cortex with the use of a device for the mechanical stimulation of the plantar support zones].
abstract: Studies of the control movements mechanisms have been performed in the interest of space medicine were the basis for the development of the concept about the leading role of the support afferent input in the regulation of postural-tonic system of mammals. Introduction of functional magnetic resonance imaging (fMRI) made it possible to investigate in-vivo brain mapping during stimulation of support afferent input. The aim of our study was to investigate brain activation due to mechanical support stimulation of the soles with the special device "Korvit". 12 healthy participants (6 women, 6 men; average age = 28.8 years) were scanned. fMRI protocol for each person consisted of 2 different blocked paradigms: soles stimulation in stance imitation (1) and slow walking imitation (2) modes. The results were analyzed with statistical program SPM5 for each person and then for the whole group. In all our paradigms there was significant (P(correct) < 0.05 for cluster level) activation of primary somatosensory, premotor and dorsolateral cortex, insula. During the stance imitation mode, extensive prefrontal cortex activation was observed; during the slow walking imitation mode there was activation of different primary and secondary sensorimotor cortex areas.
authors.forename: E I
authors.initials: EI
authors.lastname: Kremneva
authors.forename: L A
authors.initials: LA
authors.lastname: Chernikova
authors.forename: R N
authors.initials: RN
authors.lastname: Konovalov
authors.forename: M V
authors.initials: MV
authors.lastname: Krotenkova
authors.forename: I V
authors.initials: IV
authors.lastname: Saenko
authors.forename: I B
authors.initials: IB
authors.lastname: Kozlovskaia
mesh_terms: D000328:Adult; D000337:Aerospace Medicine / Q000379:methods; D001931:Brain Mapping; D056228:Feedback, Sensory / Q000502:physiology*; D005260:Female; D005528:Foot / Q000502:physiology; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D013003:Somatosensory Cortex / Q000502:physiology*; D016138:Walking / Q000502:physiology