title: Cypermethrin-induced toxic effect on glycogen metabolism in estuarine clam, marcia opima (gmelin, 1791) of ratnagiri coast, maharashtra.
abstract: Cypermethrin is a synthetic pyrethroid class of insecticide. Toxic effects of cypermethrin were studied by selecting Marcia opima as an animal model. Cypermethrins effect on the total glycogen content of mantle, gill, foot, hepatopancreas, male gonad and a female gonad of an estuarine clam, Marcia opima was examined. The clams were exposed to 1.58 ppm cypermethrin for acute and 1/10th of that concentration for chronic treatment. It was found that there was a decrease in glycogen content in various tissues as compared to control. In LC(0) and LC(50) groups, glycogen was decreased in all tissues except in hepatopancreas compared to control. This decrease is greater in mantle, gill, and foot in LC(50) group than the decrease in those tissues of LC(0) group. In chronic exposure it was found that glycogen was decreased in mantle, foot, male gonad, and female gonad when compared to the control group except in gill and hepatopancreas. Decrease in glycogen content indicates greater utilization of glycogen for metabolic purposes and too combat with cypermethrin stress. The significant increase in glycogen content in gill and hepatopancreas may be a reaction to the increase in energy demand.
authors.affiliation: Department of Zoology, R.P. Gogate College of Arts and Science and R.V. Jogalekar College of Commerce, Maharashtra, Ratnagiri 415612, India.
authors.forename: Medha
authors.initials: M
authors.lastname: Tendulkar
authors.forename: Arvind
authors.initials: A
authors.lastname: Kulkarni