title: Chronic proliferative rhinitis associated with Salmonella enterica subspecies diarizonae serovar 61:k:1, 5, (7) in sheep in Spain.
abstract: A chronic proliferative rhinitis in sheep associated with Salmonella enterica subspecies diarizonae serovar 61:k:1, 5, (7) is described. Ten adult sheep from eight traditionally managed Rasa Aragonesa flocks located in Aragon (Spain) were studied. Clinical signs began with bilateral thick mucus nasal discharge, wheezing and snoring and progressed to partial or complete obstruction of the nostrils. Necropsy examination revealed swollen ventral nasal turbinates with a roughened mucosal surface partially covered by small polyps. Histopathology revealed chronic proliferative rhinitis with a predominant population of neutrophils that infiltrated the mucosal epithelium. Plasma cells and macrophages were present in the lamina propria. Organisms expressing Salmonella antigen immunohistochemically were detected within epithelial cells. Salmonella enterica subspecies diarizonae serovar 61:k:1, 5, (7) was isolated as a sole microorganism from nasal swabs taken from five animals. The implication of finding this bacterium in various diseases in sheep and its role as a potential zoonosis are discussed.
authors.affiliation: Departamento de Patología Animal, Universidad de Zaragoza, Zaragoza, Spain.
authors.forename: D
authors.initials: D
authors.lastname: Lacasta
authors.forename: L M
authors.initials: LM
authors.lastname: Ferrer
authors.forename: J J
authors.initials: JJ
authors.lastname: Ramos
authors.forename: J P
authors.initials: JP
authors.lastname: Bueso
authors.forename: M
authors.initials: M
authors.lastname: Borobia
authors.forename: M
authors.initials: M
authors.lastname: Ruiz de Arcaute
authors.forename: L
authors.initials: L
authors.lastname: Figueras
authors.forename: J M
authors.initials: JM
authors.lastname: González-Sainz
authors.forename: M
authors.initials: M
authors.lastname: De Las Heras
mesh_terms: D000818:Animals; D049109:Cell Proliferation; D002908:Chronic Disease; D009504:Neutrophils / Q000473:pathology; D011127:Polyps / Q000473:pathology; D012220:Rhinitis / Q000382:microbiology / Q000473:pathology / Q000662:veterinary*; D012481:Salmonella Infections, Animal / Q000382:microbiology* / Q000473:pathology; D019779:Salmonella enterica / Q000302:isolation & purification*; D012756:Sheep; D012757:Sheep Diseases / Q000382:microbiology* / Q000473:pathology; D013030:Spain / Q000453:epidemiology; D014420:Turbinates / Q000473:pathology