title: Femoral fractures in osteoporotic patients on bisphosphonates. A case report.
abstract: Osteoporotic fractures and particularly hip fractures represent a considerable burden of illness in the elderly. Bisphosphonates (BP) have been used extensively over the past decade and a half for the management of osteoporosis with considerable clinical benefit in the reduction of fragility fractures. Although not apparent in clinical trials, rare associations of subtrochanteric atypical femoral fractures (AFF) have been reported postmarketing, often after long-term BP therapy. Here, we report a well-characterized Asian female patient with bilateral AFF after long-term etidronate and alendronate therapy.
authors.affiliation: Family Medicine Department, King Abdul-Aziz medical city, Riyadh, Kingdom of Saudi Arabia. fahad_alshahrani@yahoo.com
authors.forename: Fahad
authors.initials: F
authors.lastname: Alshahrani
authors.forename: David
authors.initials: D
authors.lastname: Kendler
mesh_terms: D000368:Aged; D019386:Alendronate / Q000008:administration & dosage / Q000009:adverse effects*; D050071:Bone Density Conservation Agents / Q000008:administration & dosage / Q000009:adverse effects*; D012968:Etidronic Acid / Q000008:administration & dosage / Q000009:adverse effects*; D005260:Female; D005264:Femoral Fractures / Q000139:chemically induced*; D006621:Hip Joint / Q000000981:diagnostic imaging; D006801:Humans; D010024:Osteoporosis / Q000188:drug therapy; D058866:Osteoporotic Fractures / Q000139:chemically induced*; D010388:Pelvis / Q000000981:diagnostic imaging; D011859:Radiography
chemical_list: D050071:Bone Density Conservation Agents; D012968:Etidronic Acid; D019386:Alendronate