title: [Pluripotent stem cells for cell replacement therapy of diabetes].
abstract: The use of pluripotent stem cells (PSCs) harbours great potential for a future                     use in the cell replacement therapy of diabetes mellitus. The in vitro                     differentiation of human or mouse embryonic stem cells has yielded pancreatic                     progenitor cells, but not authentic insulin-producing beta cells. Induced                     pluripotent cells are a class of a pluripotent stem cells potentially suited as                     a cell source for cell replacement therapy. These patient specific pluripotent                     cells are generated by reprogramming but unfortunately accumulate genetic and                     epigenetic errors during reprogramming, precluding their use for therapeutic                     purposes in humans.
authors.affiliation: Institut für Klinische Biochemie, Medizinische Hochschule Hannover, Germany. clinbiochem@mh-hannover.de
authors.forename: O
authors.initials: O
authors.lastname: Naujok
authors.forename: S
authors.initials: S
authors.lastname: Lenzen
mesh_terms: D000818:Animals; D003920:Diabetes Mellitus / Q000601:surgery*; D006801:Humans; D051379:Mice; D039904:Pluripotent Stem Cells / Q000637:transplantation*