title: The EU-ADR corpus: annotated drugs, diseases, targets, and their relationships.
abstract: Corpora with specific entities and relationships annotated are essential to train and evaluate text-mining systems that are developed to extract specific structured information from a large corpus. In this paper we describe an approach where a named-entity recognition system produces a first annotation and annotators revise this annotation using a web-based interface. The agreement figures achieved show that the inter-annotator agreement is much better than the agreement with the system provided annotations. The corpus has been annotated for drugs, disorders, genes and their inter-relationships. For each of the drug-disorder, drug-target, and target-disorder relations three experts have annotated a set of 100 abstracts. These annotated relationships will be used to train and evaluate text-mining software to capture these relationships in texts.
authors.affiliation: Dept. of Medical Informatics, Erasmus University Medical Center, Rotterdam, The Netherlands. e.vanmulligen@erasmusmc.nl
authors.forename: Erik M
authors.initials: EM
authors.lastname: van Mulligen
authors.forename: Annie
authors.initials: A
authors.lastname: Fourrier-Reglat
authors.forename: David
authors.initials: D
authors.lastname: Gurwitz
authors.forename: Mariam
authors.initials: M
authors.lastname: Molokhia
authors.forename: Ainhoa
authors.initials: A
authors.lastname: Nieto
authors.forename: Gianluca
authors.initials: G
authors.lastname: Trifiro
authors.forename: Jan A
authors.initials: JA
authors.lastname: Kors
authors.forename: Laura I
authors.initials: LI
authors.lastname: Furlong
mesh_terms: D057225:Data Mining / Q000379:methods*; D016208:Databases, Factual; D004282:Documentation; D004358:Drug Therapy / Q000145:classification; D006801:Humans; D020407:Internet; D008490:Medical Informatics / Q000379:methods*; D004364:Pharmaceutical Preparations / Q000145:classification; D014584:User-Computer Interface
chemical_list: D004364:Pharmaceutical Preparations