title: [Significance of the initial state of the murine liver for the development of consequences after the combined action of the factors of different nature].
abstract: The search of the most significant parameters of the liver initial state of mice Balb/c (males) for the development of the biological consequences under a combined action of the Tween-80 (0.3% solution) in the 10% solution of the aqueous acetone and X-rays at the doses of 4 and 5 Gy during one month after exposure was performed by means of the software program for the experimental data analysis. The study has shown both the absence of the same correlation relationships and the existence of two groups of relationships in terms of the coefficient correlation values under the alteration of the X-ray dose. The assumption has been made about different mechanisms underlying regulation of the biochemical process in the murine liver after the combined action of low-toxicity chemical agents at low doses and X-rays irradiation at sublethal doses, whose contribution to the development of effects of different factors depends on the radiation dose.
authors.forename: M V
authors.initials: MV
authors.lastname: Kozlov
authors.forename: K M
authors.initials: KM
authors.lastname: Marakulina
authors.forename: L N
authors.initials: LN
authors.lastname: Shishkina
mesh_terms: D000818:Animals; D001837:Body Weights and Measures; D050356:Lipid Metabolism / Q000187:drug effects* / Q000528:radiation effects; D015227:Lipid Peroxidation / Q000187:drug effects* / Q000528:radiation effects; D008099:Liver / Q000187:drug effects* / Q000378:metabolism* / Q000528:radiation effects; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D011136:Polysorbates / Q000633:toxicity*; D011829:Radiation Dosage; D014965:X-Rays
chemical_list: D011136:Polysorbates