title: Laboratory enamel fluoride uptake from fluoride products.
abstract: OBJECTIVE
  To evaluate the fluoride concentration in enamel after the use of different fluoride products and 48 hours after the cessation of fluoride use.
  
  
  METHODS
  16 enamel slabs were divided and treated for 15 days as following: Group A, with an amine fluoride toothpaste and mouthrinse (1400 and 250 mg/L(-1), respectively); Group B, with an amine fluoride toothpaste (1400 mg/L(-1)) and mouthrinse without fluoride; Group C, with a sodium fluoride toothpaste (1400 mg/L(-1)) and mouthrinse (250 mg/L(-1)). Chemical biopsy and multiple means were used to determine fluoride concentration. The data were statistically analyzed using the two-way ANOVA and Tukey HSD tests (P<0.05).
  
  
  RESULTS
  After 15 days of fluoride product use, Group A samples had the highest fluoride uptake (0.19 microg mm(-2)) (P<0.05). 48 hours after the interruption of fluoride product usage, a higher fluoride concentration was found in Group A samples. Although all fluoride products led to an enamel uptake, amine fluoride products promoted the most effective long-term uptake.
authors.affiliation: Dental Institute, University of Sassari, Viale San Pietro 43/C I-07100 Sassari, Italy. gcampus@uniss.it
authors.forename: Guglielmo
authors.initials: G
authors.lastname: Campus
authors.forename: Maria Grazia
authors.initials: MG
authors.lastname: Cagetti
authors.forename: Nadia
authors.initials: N
authors.lastname: Spano
authors.forename: Stefania
authors.initials: S
authors.lastname: Denurra
authors.forename: Fabio
authors.initials: F
authors.lastname: Cocco
authors.forename: Maurizio
authors.initials: M
authors.lastname: Bossù
authors.forename: Maria Ignazia
authors.initials: MI
authors.lastname: Pilo
authors.forename: Gavino
authors.initials: G
authors.lastname: Sanna
authors.forename: Franklin
authors.initials: F
authors.lastname: García-Godoy
mesh_terms: D000588:Amines / Q000032:analysis / Q000493:pharmacokinetics; D002327:Cariostatic Agents / Q000032:analysis / Q000493:pharmacokinetics*; D003743:Dental Enamel / Q000378:metabolism*; D004311:Double-Blind Method; D005459:Fluorides / Q000032:analysis / Q000493:pharmacokinetics*; D006801:Humans; D017736:Ion-Selective Electrodes; D008422:Materials Testing; D009067:Mouthwashes / Q000008:administration & dosage*; D011199:Potentiometry; D012464:Saliva, Artificial / Q000737:chemistry; D012969:Sodium Fluoride / Q000032:analysis / Q000493:pharmacokinetics; D013997:Time Factors; D014100:Toothpastes / Q000008:administration & dosage*
chemical_list: D000588:Amines; D002327:Cariostatic Agents; D009067:Mouthwashes; D012464:Saliva, Artificial; D014100:Toothpastes; D012969:Sodium Fluoride; D005459:Fluorides