title: A newly developed container for safe, easy, and cost-effective overnight transportation of tissues and organs by electrically keeping tissue or organ temperature at 3 to 6°C.
abstract: BACKGROUND
  As there is only one skin procurement organization in Japan the Japan Skin Bank Network (JSBN), all skin grafts procured in Japan are sent by a commercialized delivery system. Preliminarily, bottles containing saline were transported in a cardboard box using a so-called "cooled home delivery service" using a truck with a refrigerated cargo container. During transportation the temperature in the cardboard box increased to 18°C in summer and decreased to -5°C in winter. For these reasons, we investigated whether a newly developed container "Medi Cube" would be useful to transport skin grafts.
  
  
  OBJECTIVE
  Four bottles with a capacity of 300 mL containing 150 mL of saline in a Medi Cube container were transported from Osaka to the JSBN in Tokyo between 4 PM and 10 AM using a commercialized cooled home delivery service. Two bottles were transported in a Medi Cube container without phase change materials (PCM) in winter and summer, respectively. Another two bottles were transported in the Medi Cube with PCMs in winter. The temperatures inside saline, inside a transportation container, and outside the container, and air temperature were monitored continuously with a recordable thermometer.
  
  
  RESULTS
  The temperatures inside saline and inside a Medi Cube container were maintained between 3 and 6°C, even when the temperature outside the container increased during parking. The temperature inside a Medi Cube container without PCM decreased to -3°C when the inside of the cargo container was overcooled in winter. However, the temperatures inside saline and inside a Medi Cube container with PCM were between 3 and 6°C, even when the temperature outside the container decreased to below 0°C in winter.
  
  
  CONCLUSIONS
  A Medi Cube container with PCM provided a safe, easy, and cost-effective method for overnight transportation of skin grafts.
authors.affiliation: Medical Center for Translational Research, Osaka University Hospital, Osaka, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Ohkawara
authors.forename: T
authors.initials: T
authors.lastname: Kitagawa
authors.forename: N
authors.initials: N
authors.lastname: Fukushima
authors.forename: T
authors.initials: T
authors.lastname: Ito
authors.forename: Y
authors.initials: Y
authors.lastname: Sawa
authors.forename: T
authors.initials: T
authors.lastname: Yoshimine
mesh_terms: D003080:Cold Temperature; D003362:Cost-Benefit Analysis; D004560:Electricity; D004867:Equipment Design; D017048:Health Care Costs; D006801:Humans; D009926:Organ Preservation / Q000191:economics / Q000295:instrumentation / Q000379:methods*; D012621:Seasons; D016038:Skin Transplantation / Q000191:economics; D012965:Sodium Chloride; D013821:Thermometers; D013997:Time Factors; D020858:Tissue and Organ Harvesting / Q000191:economics; D009927:Tissue and Organ Procurement / Q000191:economics; D014186:Transportation / Q000191:economics
chemical_list: D012965:Sodium Chloride