title: Parent perceived quality of life is age-dependent in children with food allergy.
abstract: BACKGROUND
  Food allergy in children significantly affects their quality of life. Its impact can be analyzed by quality of life questionnaires.
  
  
  OBJECTIVE
  The aim of our study was to validate the French version of disease-specific questionnaires and to evaluate the quality of life in children with IgE-mediated food allergy.
  
  
  METHODS
  Two validated food allergy-specific questionnaires for quality of life, the parent's and children's forms (FAQLQ-PF and FAQLQ-CF), were translated from English to French and submitted to children with food allergy and their parents. Questionnaires were analyzed in terms of emotional impact, food anxiety, and social and food limitations. NCT 01480427.
  
  
  RESULTS
  Sixty-two parents of children aged 0-12 yrs answered the FAQLQ-PF, and 32 children aged 8-12 yrs the FAQLQ-CF. Construct validity of both questionnaires was assessed by correlation between the FAQLQs and FAIM (r = 0.85 and 0.84, respectively). Both FAQLQs had good internal consistency (Cronbach's α = 0.748 and 0.67, respectively). Young children (0-3 yrs old) showed better quality of life scores than older children (FAQLQ-PF global score: p = 0.02). Worse scores were also shown among children with previous severe systemic reactions (FAQLQ-PF global score: p = 0.039), the ones with an allergic mother (FAQLQ-PF global score: p = 0.002), or allergic siblings (FAQLQ-PF emotional impact score: p = 0.034), the ones with multiple food allergy (more than 1 food) (FAQLQ-PF anxiety score: p = 0.04) and among the girls (FAQLQ-CF global score: p = 0.031).
  
  
  CONCLUSIONS
  Older children, the ones with severe systemic reactions, or with mothers or siblings also affected by allergies, as well as girls, and children with multiple food allergies show worse quality of life scores.
authors.affiliation: Division of Allergology, Immunology and Rhumatology, Department of Paediatrics, University Hospital Center and University of Lausanne, Lausanne, Switzerland. jacqueline.wassenberg@chuv.ch
authors.forename: Jacqueline
authors.initials: J
authors.lastname: Wassenberg
authors.forename: Marie-Madeleine
authors.initials: MM
authors.lastname: Cochard
authors.forename: Audrey
authors.initials: A
authors.lastname: Dunngalvin
authors.forename: Pierluigi
authors.initials: P
authors.lastname: Ballabeni
authors.forename: Bertine M J
authors.initials: BM
authors.lastname: Flokstra-de Blok
authors.forename: Christopher J
authors.initials: CJ
authors.lastname: Newman
authors.forename: Michael
authors.initials: M
authors.lastname: Hofer
authors.forename: Philippe A
authors.initials: PA
authors.lastname: Eigenmann
mesh_terms: D000367:Age Factors; D002648:Child; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D005260:Female; D005512:Food Hypersensitivity / Q000523:psychology*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D010290:Parents; D010465:Perception; D011788:Quality of Life; D011795:Surveys and Questionnaires; D013557:Switzerland