title: Relation between indices of end-organ damage and mean platelet volume in hypertensive patients.
abstract: Mean platelet volume (MPV) has been recognized as an independent risk factor of hypertension. Hypertensive end-organ damage worsens the prognosis in hypertensive patients. We aimed to investigate the relationship between MPV levels and subclinical end-organ damage in hypertensive patients. One hundred and sixteen hypertensive patients (81 women, 35 men, with a mean age of 53 ± 11) were included in the study. There was no correlation between MPV and left-ventricular mass index (LVMI) (r = 0.145; P = 0.14) or albuminuria (r = 0.009; P = 0.93). Among the individuals that had grade I and grade II retinopathy, MPV levels (8.3 ± 2 fL, 8.2 ± 1.3 fL; P = 0.28) were similar either. We concluded that there was no correlation between MPV and markers of end-organ damage in hypertensive patients.
authors.affiliation: Duzce Medical School, Department of Cardiology, Düzce University, Konuralp, Düzce, Turkey. drserkanbulur@yahoo.com
authors.forename: Serkan
authors.initials: S
authors.lastname: Bulur
authors.forename: Halil Ibrahim
authors.initials: HI
authors.lastname: Önder
authors.forename: Yusuf
authors.initials: Y
authors.lastname: Aslantas
authors.forename: Ismail
authors.initials: I
authors.lastname: Ekinozu
authors.forename: Ali Çağr
authors.initials: AÇ
authors.lastname: Kiliç
authors.forename: Sübhan
authors.initials: S
authors.lastname: Yalcin
authors.forename: Şule
authors.initials: Ş
authors.lastname: Bulur
authors.forename: Hakan
authors.initials: H
authors.lastname: Ozhan
mesh_terms: D000328:Adult; D000419:Albuminuria / Q000473:pathology; D015415:Biomarkers; D001792:Blood Platelets / Q000473:pathology*; D001794:Blood Pressure; D048429:Cell Size; D005260:Female; D006352:Heart Ventricles / Q000473:pathology; D006801:Humans; D006973:Hypertension / Q000473:pathology*; D058437:Hypertensive Retinopathy / Q000473:pathology; D008297:Male; D008875:Middle Aged; D010976:Platelet Count; D012307:Risk Factors
chemical_list: D015415:Biomarkers