title: First total synthesis of (+)-indicanone.
abstract: The first total synthesis of the guaiane-type sesquiterpene, (+)-indicanone (1), isolated from the root of Wikstroemia indica, was accomplished based on the rhodium(I)-catalyzed Pauson-Khand-type reaction of the allenyne derivative, which was derived from (+)-limonene. This total synthesis unambiguously confirmed the complete structure of (+)-indicanone involving its absolute stereochemistry.
authors.affiliation: Division of Pharmaceutical Sciences, Graduate School of Natural Science and Technology, Kanazawa University, Kakuma-machi, Kanazawa, 920-1192, Japan.
authors.forename: Yujiro
authors.initials: Y
authors.lastname: Hayashi
authors.forename: Kumiko
authors.initials: K
authors.lastname: Ogawa
authors.forename: Fuyuhiko
authors.initials: F
authors.lastname: Inagaki
authors.forename: Chisato
authors.initials: C
authors.lastname: Mukai
mesh_terms: D002384:Catalysis; D015394:Molecular Structure; D012717:Sesquiterpenes / Q000138:chemical synthesis*; D013237:Stereoisomerism; D032365:Wikstroemia / Q000737:chemistry
chemical_list: D012717:Sesquiterpenes; C574913:indicanone