title: Maternal cardiac arrest and perimortem caesarean delivery: evidence or expert-based?
abstract: OBJECTIVE
  To examine the outcomes of maternal cardiac arrest and the evidence for the 4-min time frame from arrest to perimortem caesarean delivery (PMCD) recommended in current resuscitation and obstetric guidelines.
  
  
  METHODS
  Review and data extraction from all reported maternal cardiac arrests occurring prior to delivery (1980-2010). Cases were included if they provided details regarding both the event and outcomes. Outcomes of arrest were assessed using survival, Cerebral Performance Category (CPC) and maternal/neonatal harm/benefit from PMCD. Outcome measures were maternal and neonatal survival.
  
  
  RESULTS
  Of 1594 manuscripts screened, 156 underwent full review. Data extracted from 80 relevant papers yielded 94 included cases. Maternal outcome: 54.3% (51/94) of mothers survived to hospital discharge, 78.4% (40/51) with a CPC of 1/2. PMCD was determined to have been beneficial to the mother in 31.7% of cases and was not harmful in any case. In-hospital arrest and PMCD within 10 min of arrest were associated with better maternal outcomes (ORs 5.17 and 7.42 respectively, p<0.05 both). Neonatal outcome: mean times from arrest to delivery were 14±11 min and 22±13 min in survivors and non-survivors respectively (receiver operating area under the curve 0.729). Neonatal survival was only associated with in-hospital maternal arrest (OR 13.0, p<0.001).
  
  
  CONCLUSIONS
  Treatment recommendations should include a low admission threshold to a highly monitored area for pregnant women with cardiorespiratory decompensation, good overall performance of resuscitation and delivery within 10 min of arrest. Cognitive dissonance may delay both situation recognition and the response to maternal collapse.
authors.affiliation: The General Intensive Care Unit of the Shaare Zedek Medical Centre, Jerusalem, Israel. einav_s@szmc.org.il
authors.forename: Sharon
authors.initials: S
authors.lastname: Einav
authors.forename: Nechama
authors.initials: N
authors.lastname: Kaufman
authors.forename: Hen Y
authors.initials: HY
authors.lastname: Sela
mesh_terms: D002585:Cesarean Section; D016757:Death, Sudden, Cardiac; D005260:Female; D006801:Humans; D063130:Maternal Death; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular