title: (1)H MR Spectroscopy in Gliomatosis: Is there a Sensitivity Issue?
abstract: Objective. (1)H MR spectroscopy (MRS) is widely performed for assessment of brain tumours and is considered a highly sensitive technique capable of differentiating benign from malignant conditions and tumour grading. Method. We present a case of a 69 year old woman who was suspected to have gliomatosis on MRI. Results. MRS performed using single voxel and chemical shift/multivoxel techniques was within normal limits. A repeat scan 6 months later showed progressive disease, and biopsy was performed that proved the diagnosis of glioblastoma. Conclusion. Normal MRS in a patient with suspicion of gliomatosis on MRI should not reassure clinicians into assuming a benign aetiology or a good prognosis in short term.
authors.affiliation: Department of Clinical Radiology, Ninewells Hospital and Medical School, NHS Tayside, Dundee DDI 9SY, UK.
authors.forename: M
authors.initials: M
authors.lastname: Szewczyk-Bieda
authors.forename: A K
authors.initials: AK
authors.lastname: Kanodia
authors.forename: G
authors.initials: G
authors.lastname: Main
authors.forename: M S
authors.initials: MS
authors.lastname: Eljamel