title: [Simultaneous determination of bromate and perchlorate in vegetable by ion chromatography tandem mass spectrometry].
abstract: OBJECTIVE
  To develop a method for simultaneous determination of bromate and perchiorate in vegetable using ion chromatography tandem mass spectrometry.
  
  
  METHODS
  Target ions in vegetable matrix were extracted by water and purified using a GCB cartridge. With the hydrophilic Ion Pac AS19 column and linear gradient potassium hydroxide used as eluent, bromate and perchlorate were analyzed by a triple quadrupole mass spectrometer under negative electronspray ionization mode and multiple reaction monitoring (MRM). Internal standard calibration was used for quantification.
  
  
  RESULTS
  Good linearity was achieved for bromate and perchlorate over the range of 0.1- 50 microg/L and 0.05-50 microg/L, respectively, with correlation coefficients R2 > 0.998. The quantification limits of the method were 2.5 microg/kg and 0.7 microg/kg for bromate and perchlorate, respectively. Mean recoveries of two target analytes (spiked at three concentration levels in 5 kinds of vegetables) ranged from 80.3% to 124%, with within-day precisions no more than 21.4% and intraday precisions no more than 12.2%.
  
  
  CONCLUSIONS
  This method could be applied in the simultaneous detection of bromate and perchlorate in vegetable.
authors.affiliation: College of Food Science and Engineering, WuHan Polytechnic University, Wuhan 430030, China. yangjiajia2450@163.com
authors.forename: Jiajia
authors.initials: J
authors.lastname: Yang
authors.forename: Yi
authors.initials: Y
authors.lastname: Yang
authors.forename: Jing
authors.initials: J
authors.lastname: Zhang
authors.forename: Bing
authors.initials: B
authors.lastname: Shao
authors.forename: Yongning
authors.initials: Y
authors.lastname: Wu
mesh_terms: D001959:Bromates / Q000032:analysis*; D002852:Chromatography, Ion Exchange / Q000379:methods; D005506:Food Contamination / Q000032:analysis*; D010472:Perchlorates / Q000032:analysis*; D053719:Tandem Mass Spectrometry / Q000379:methods; D014675:Vegetables / Q000737:chemistry*
chemical_list: D001959:Bromates; D010472:Perchlorates; C494474:perchlorate