title: One-pot asymmetric synthesis of 2- and 2,3-disubstituted tetrahydrofuran derivatives.
abstract: A novel and convenient one-pot asymmetric synthesis of 2- and 2,3-disubstituted tetrahydrofurans has been achieved in 56-81% yields and 86-99% ee from aliphatic and aromatic aldehydes via an allyl/crotyl/alkoxyallylboration-hydroboration-iodination-cyclization reaction sequence.
authors.affiliation: Herbert C. Brown Center for Borane Research, Department of Chemistry, Purdue University, 560 Oval Drive, West Lafayette, Indiana 47907-2084, USA. chandran@purdue.edu
authors.forename: P Veeraraghavan
authors.initials: PV
authors.lastname: Ramachandran
authors.forename: Hari N G
authors.initials: HN
authors.lastname: Nair
authors.forename: Pravin D
authors.initials: PD
authors.lastname: Gagare