title: Optical coherence tomography assessment of edge dissections after drug-eluting stent implantation in coronary artery.
abstract: BACKGROUND
  Edge dissections after coronary stent implantation are associated with increased short-term risk of major adverse cardiovascular events. The incidence and outcome of edge dissections after coronary stent implantation were reportedly different using different imaging techniques. We used optical coherence tomography (OCT) to assess the incidence, morphological findings and related factors of edge dissections after drug-eluting stent (DES) implantation.
  
  
  METHODS
  Totally 42 patients with 43 de novo lesions in 43 native arteries undergoing DES implantation with OCT imaging were enrolled in this study.
  
  
  RESULTS
  Nine edge dissections were detected in 43 arteries after DES implantation. There were four morphological patterns of stent edge dissections indentified in this study: (1) superficial intimal tears (n = 3), (2) subintimal dissections (n = 4), (3) split of media (n = 1), (4) disruption of the fibrotic cap of plaque (n = 1). Stent edge expansion and stent expansion were both higher in the group with dissections than those in the group without dissections (1.682 ± 0.425 vs. 1.229 ± 0.285, P = 0.0290; 1.507 ± 0.445 vs. 1.174 ± 0.265, P = 0.0072).
  
  
  CONCLUSIONS
  The incidence of stent edge dissections detected by OCT was 21%. Stent edge dissection is related with stent edge expansion and stent expansion.
authors.affiliation: Department of Cardiology, Chinese People's Liberation Army General Hospital, Beijing 100853, China.
authors.forename: Jun
authors.initials: J
authors.lastname: Guo
authors.forename: Yun-dai
authors.initials: YD
authors.lastname: Chen
authors.forename: Feng
authors.initials: F
authors.lastname: Tian
authors.forename: Hong-bin
authors.initials: HB
authors.lastname: Liu
authors.forename: Lian
authors.initials: L
authors.lastname: Chen
authors.forename: Zhi-jun
authors.initials: ZJ
authors.lastname: Sun
authors.forename: Yi-hong
authors.initials: YH
authors.lastname: Ren
authors.forename: Qin-hua
authors.initials: QH
authors.lastname: Jin
authors.forename: Chang-fu
authors.initials: CF
authors.lastname: Liu
authors.forename: Bao-shi
authors.initials: BS
authors.lastname: Han
authors.forename: Lu-yue
authors.initials: LY
authors.lastname: Gai
authors.forename: Ting-shu
authors.initials: TS
authors.lastname: Yang
mesh_terms: D000368:Aged; D000784:Aortic Dissection / Q000175:diagnosis*; D015906:Angioplasty, Balloon, Coronary / Q000009:adverse effects*; D003323:Coronary Aneurysm / Q000175:diagnosis*; D054855:Drug-Eluting Stents / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000175:diagnosis*; D041623:Tomography, Optical Coherence / Q000379:methods*