title: Atypical central serous retinopathy in a patient with latent tuberculosis.
abstract: A 32-year-old Afro-Caribbean male presented with a 4 month history of blurred vision and distortion in his right eye. Fundus examination showed multiple pigment epithelial detachments which progressed over 2 months of observation to a large serous detachment of the macula. Fundus fluorescein angiography (FFA) showed multi-focal hyperfluorescence in the early phase which increased in the later stages. A diagnosis of multi-focal central serous retinopathy (CSR) was made. Due to the size of CSR and atypical findings on FFA further investigations including a T-spot test were performed. The T-spot test was reported as strongly positive and following discussion with the respiratory physicians he was started on empiric antituberculous therapy. Over the next 6 weeks, the patient had a significant visual improvement to 6/9 with resolution of the serous detachment.
authors.affiliation: Ophthalmology Department, Ipswich Hospital NHS Trust, Ipswich, UK. deepak_vayalam@hotmail.com
authors.forename: Deepak
authors.initials: D
authors.lastname: Vayalambrone
authors.forename: Tsveta
authors.initials: T
authors.lastname: Ivanova
authors.forename: Aseema
authors.initials: A
authors.lastname: Misra
mesh_terms: D000328:Adult; D000995:Antitubercular Agents / Q000627:therapeutic use; D056833:Central Serous Chorioretinopathy / Q000175:diagnosis* / Q000209:etiology; D003937:Diagnosis, Differential; D005451:Fluorescein Angiography; D006801:Humans; D055985:Latent Tuberculosis / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D008297:Male; D009887:Ophthalmoscopy; D041623:Tomography, Optical Coherence; D014792:Visual Acuity
chemical_list: D000995:Antitubercular Agents