title: [Systemic lupus erythematosus--still current clinical and diagnostic problem].
abstract: Systemic lupus erythematosus (SLE) is a common autoimmune disease of unknown etiology that frequently affects women of childbearing age. SLE is associated with impairments in immune system, which is a consequence of increased production of various autoantibodies. This disease is still a major diagnostic and therapeutic problem. Some hope to explain the complex etiopathogenesis of the disease creates a monitoring function of the immune system. A chance for patients are biologically targeted therapies that affect the critical stages of the disease and autoimmune inflammatory processes.
authors.affiliation: Department and Institute of Immunology and Serology, Medical University of Silesia, Katowice, Poland. karina.gesikowska@tlen.pl
authors.forename: Karina
authors.initials: K
authors.lastname: Gesikowska
authors.forename: Zdzisława
authors.initials: Z
authors.lastname: Kondera-Anasz
authors.forename: Aleksandra
authors.initials: A
authors.lastname: Mielczarek-Palacz
authors.forename: Justyna
authors.initials: J
authors.lastname: Sikora
authors.forename: Iwona
authors.initials: I
authors.lastname: Machaj
authors.forename: Marta
authors.initials: M
authors.lastname: Smycz
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000175:diagnosis* / Q000276:immunology / Q000628:therapy*