title: Ultraviolet light-induced changes of lymphatic and blood vasculature in skin and their molecular mechanisms.
abstract: Ultraviolet light in the 290- to 320-nm wavelength range (UVB) induces angiogenesis and lymphatic dysfunction in skin. This review deals with UVB-induced alterations to the blood and lymphatic systems in skin and the molecular mechanisms involved. We also discuss potential strategies to block photoageing of skin by inhibiting angiogenesis and/or promoting lymphatic vascular function.
authors.affiliation: Shiseido Research Center, Yokohama, Japan.
authors.forename: Mika
authors.initials: M
authors.lastname: Sawane
authors.forename: Kentaro
authors.initials: K
authors.lastname: Kajiya
mesh_terms: D000818:Animals; D001808:Blood Vessels / Q000473:pathology* / Q000528:radiation effects; D006801:Humans; D008027:Light; D008208:Lymphatic System; D042601:Lymphatic Vessels / Q000473:pathology* / Q000528:radiation effects; D051379:Mice; D008954:Models, Biological; D018919:Neovascularization, Physiologic / Q000528:radiation effects; D015398:Signal Transduction; D012867:Skin / Q000098:blood supply* / Q000473:pathology / Q000528:radiation effects; D015595:Skin Aging / Q000528:radiation effects*; D014466:Ultraviolet Rays