title: Multiple-locus variable-number tandem-repeat analysis of pathogenic Yersinia enterocolitica in China.
abstract: The predominant bioserotypes of pathogenic Yersinia enterocolitica in China are 2/O: 9 and 3/O: 3; no pathogenic O: 8 strains have been found to date. Multiple-Locus Variable-Number Tandem-Repeat Analysis (MLVA) based on seven loci was able to distinguish 104 genotypes among 218 pathogenic Y. enterocolitica isolates in China and from abroad, showing a high resolution. The major pathogenic serogroups in China, O: 3 and O: 9, were divided into two clusters based on MLVA genotyping. The different distribution of Y. enterocolitica MLVA genotypes maybe due to the recent dissemination of specific clones of 2/O: 9 and 3/O: 3 strains in China. MLVA was a helpful tool for bacterial pathogen surveillance and investigation of pathogenic Y. enterocolitica outbreaks.
authors.affiliation: National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, State Key Laboratory for Infectious Disease Prevention and Control, Beijing, China.
authors.forename: Xin
authors.initials: X
authors.lastname: Wang
authors.forename: Wenpeng
authors.initials: W
authors.lastname: Gu
authors.forename: Zhigang
authors.initials: Z
authors.lastname: Cui
authors.forename: Longze
authors.initials: L
authors.lastname: Luo
authors.forename: Peng
authors.initials: P
authors.lastname: Cheng
authors.forename: Yuchun
authors.initials: Y
authors.lastname: Xiao
authors.forename: Liuying
authors.initials: L
authors.lastname: Tang
authors.forename: Biao
authors.initials: B
authors.lastname: Kan
authors.forename: Huaiqi
authors.initials: H
authors.lastname: Jing
mesh_terms: D002681:China / Q000453:epidemiology; D005838:Genotype; D006801:Humans; D018598:Minisatellite Repeats; D015009:Yersinia Infections / Q000453:epidemiology / Q000235:genetics; D015008:Yersinia enterocolitica / Q000235:genetics* / Q000302:isolation & purification / Q000472:pathogenicity