title: [Zoely, a combined oral contraceptive, monophasic pill containing estradiol and nomegestrol acetate].
abstract: A new combined oral contraceptive called Zoely has just been marketed in Belgium. It contains nomegestrol acetate, a progestin known for its high contraceptive reliability based on its antigonadotropic power and long half-life. This progestin is associated with estradiol and Zoely is devoid of ethinyl estradiol, which is the usual component of the majority of combined oral contraceptives and is primarily responsible for thrombotic side effects of the pill. The compositon and type of regimen of this new oral contraceptive contribute to its efficacy and excellent clinical tolerance.
authors.affiliation: CHU de Liège. axelle.pintiaux@gmail.com
authors.forename: A
authors.initials: A
authors.lastname: Pintiaux
authors.forename: U
authors.initials: U
authors.lastname: Gaspard
authors.forename: M
authors.initials: M
authors.lastname: Nisolle
mesh_terms: D000818:Animals; D003267:Contraception / Q000009:adverse effects / Q000379:methods; D003277:Contraceptives, Oral, Combined / Q000009:adverse effects / Q000737:chemistry / Q000627:therapeutic use*; D015195:Drug Design; D004958:Estradiol / Q000008:administration & dosage* / Q000009:adverse effects; D006801:Humans; D008535:Megestrol / Q000008:administration & dosage* / Q000009:adverse effects; D009649:Norpregnadienes / Q000008:administration & dosage* / Q000009:adverse effects; D013607:Tablets
chemical_list: D003277:Contraceptives, Oral, Combined; D009649:Norpregnadienes; D013607:Tablets; D004958:Estradiol; C038501:nomegestrol acetate; D008535:Megestrol