title: Unilateral optic nerve aplasia associated with microphthalmos.
abstract: BACKGROUND
  Optic nerve aplasia is a rare developmental anomaly characterised by the congenital absence of the optic nerve, central retinal vessels and retinal ganglion cells that is seen most often in a unilaterally malformed eye.
  
  
  METHODS
  We reported a girl with a very rare anomaly of the eye, unilateral aplasia of the optic nerve and microphthalmia. We carried out a complete ophthalmological examination, A- and B-scan ultrasonography, magnetic resonance imaging (MRI) of the orbit and brain, pediatrician, neurological examinations and karyotype determination. The examined child was a third child from the third regular pregnancy, born at term (39 GS, BM 3100 g). Family ocular history was negative. The right corneal diameter was 7.5 mm and left 10 mm. On dilated fundus examination, the right eye showed the absence of op tic nerve and central retinal vessels. B-scan echography showed a small right globe (axial length 13.80 mm), normal size left globe (axial length 18.30 mm) and the absence of optic nerve on the right eye. Physical and neurological findings and karyotype was normal. MRI of the orbits and brain marked asymmetry of globe size and unilateral absence of the optic nerve. The patient is under the control of a competent ophthalmologist and prosthetic.
  
  
  CONCLUSIONS
  Further aesthetic and functional development of a young person is the primary goal in tracking this rare congenital optic nerve anomalies in the malformed eye.
authors.affiliation: Clinic for Eye Diseases, Clinical Center Nis, Nis, Serbia. gordanasb@open.telekom.rs
authors.forename: Gordana
authors.initials: G
authors.lastname: Stanković-Babić
authors.forename: Ana
authors.initials: A
authors.lastname: Oros
authors.forename: Sonja
authors.initials: S
authors.lastname: Cekić
authors.forename: Milena
authors.initials: M
authors.lastname: Vujanović
authors.forename: Rade R
authors.initials: RR
authors.lastname: Babić
mesh_terms: D005260:Female; D006801:Humans; D007223:Infant; D008850:Microphthalmos / Q000150:complications*; D009900:Optic Nerve / Q000002:abnormalities*; D012171:Retinal Vessels / Q000002:abnormalities*