title: Chemistry and biology of indoles and indazoles: a mini-review.
abstract: The present review article is related with the method of preparation, importance and medicinal application of indole and indazoles. The studies of heterocycles is an evergreen field in the branch of organic chemistry and always attract the attention of chemists working not only in the area of natural products but also in the synthetic chemistry. Moreover many useful drugs have emerged from the successful investigation carried out in this branch. The derivatives of indoles and indazoles exhibits antibacterial, anticancer, antionidants, anti-inflammatory, antidiabetic, antiviral, atniproliferative, antituberculosis, antispermetogenic activity, antipsychotic drugs etc.
authors.affiliation: Dr. Rafiq Zakaria College for Women, Aurangabad, India. Mazahar_64@rediffmail.com.
authors.forename: Nasir Ali Shafakat
authors.initials: NA
authors.lastname: Ali
authors.forename: Bashir Ahmad
authors.initials: BA
authors.lastname: Dar
authors.forename: Vidya
authors.initials: V
authors.lastname: Pradhan
authors.forename: Mazahar
authors.initials: M
authors.lastname: Farooqui
mesh_terms: D000890:Anti-Infective Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D000893:Anti-Inflammatory Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D000970:Antineoplastic Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000633:toxicity; D000975:Antioxidants / Q000138:chemical synthesis / Q000737:chemistry / Q000378:metabolism; D017209:Apoptosis / Q000187:drug effects; D004926:Escherichia coli / Q000187:drug effects; D006801:Humans; D007191:Indazoles / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D007211:Indoles / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D009169:Mycobacterium tuberculosis / Q000187:drug effects; D019001:Nitric Oxide Synthase / Q000037:antagonists & inhibitors / Q000378:metabolism; D011485:Protein Binding
chemical_list: D000890:Anti-Infective Agents; D000893:Anti-Inflammatory Agents; D000970:Antineoplastic Agents; D000975:Antioxidants; D007191:Indazoles; D007211:Indoles; D019001:Nitric Oxide Synthase