title: [Ergoferon and improvement of etiopathogenetic therapy of influenza and acute respiratore viral infection in adults].
abstract: The therapeutic efficacy and tolerance of ergoferon, an antiviral medication combining anti-inflammatory and antihistaminic actions were estimated in the treatment of adult patients with influenza and acute respiratory viral infection. Ergoferon was shown to stimulate production of endogenous interferon-alpha and interferon-gamma and to normalize the T-lymphocyte subpopulation composition and histamine level, that made it possible to lower the time of the disease clinical signs development and to prevent typical complications and chronic somatic pathology exacerbation.
authors.forename: V K
authors.initials: VK
authors.lastname: Verevshchikov
authors.forename: V M
authors.initials: VM
authors.lastname: Borzunov
authors.forename: E K
authors.initials: EK
authors.lastname: Shemiakina
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000906:Antibodies / Q000276:immunology / Q000627:therapeutic use*; D000998:Antiviral Agents / Q000276:immunology / Q000627:therapeutic use*; D016516:CD4-CD8 Ratio; D015496:CD4-Positive T-Lymphocytes / Q000187:drug effects / Q000276:immunology; D018414:CD8-Positive T-Lymphocytes / Q000187:drug effects / Q000276:immunology; D005260:Female; D006633:Histamine Antagonists / Q000276:immunology / Q000627:therapeutic use; D006801:Humans; D007251:Influenza, Human / Q000188:drug therapy* / Q000276:immunology; D007369:Interferon Inducers / Q000276:immunology / Q000627:therapeutic use*; D016898:Interferon-alpha / Q000096:biosynthesis; D007371:Interferon-gamma / Q000096:biosynthesis; D007694:Killer Cells, Natural / Q000187:drug effects / Q000276:immunology; D008297:Male; D008875:Middle Aged; D012141:Respiratory Tract Infections / Q000188:drug therapy* / Q000276:immunology; D055815:Young Adult
chemical_list: D000906:Antibodies; D000998:Antiviral Agents; D006633:Histamine Antagonists; D007369:Interferon Inducers; D016898:Interferon-alpha; C000621422:ergoferon; D007371:Interferon-gamma