title: Effect of stroke volume variability- guided intraoperative fluid restriction on gastrointestinal functional recovery.
abstract: To investigate the effect of stroke volume variability(SVV)-guided intraoperative fluid restriction on gastrointestinal functional recovery and postoperative outcome after gastrointestinal surgery. Forty ASA I-II patients undergoing elective gastrointestinal surgery were randomly divided into 2 groups (n=20 each):group A routine fluid administration and group B restricted fluid administration. SW value was maintained at 5-7 in group A and 11-13 in group B. All patients received general anesthesia, tracheal catheterized and mechanical ventilation. Hemodynamic monitoring parameters (MBP, HR, CVP, CO) were noted at 5 time points. The hemodynamic parameters were maintained within normal limits during operation in both groups. The intraoperative intravenous fluid volume in group B was significant less than in group A (p<0.01).Urine output in group A was significant less than in group B (p<0.05). Stroke volume variation measured from Edwards Flotrac sensor and Edwards Vigileo monitor could be a security and sensitive parameter as an index of volume administration. In elective gastrointestinal surgery, volume resuscitation with a goal SVV of11-13 not only reduced intravenous fluid volume but also maintained the stable hemodynamic and tissue perfusion, enhanced gastrointestinal functional recovery and reduced the length of hospital stay
authors.affiliation: Department of Anesthesiology, Zhejiang University, Hangzhou, China.
authors.forename: Ping
authors.initials: P
authors.lastname: Wang
authors.forename: Hong-Wei
authors.initials: HW
authors.lastname: Wang
authors.forename: Tai-Di
authors.initials: TD
authors.lastname: Zhong
mesh_terms: D000328:Adult; D000368:Aged; D000704:Analysis of Variance; D001794:Blood Pressure; D001810:Blood Volume; D002681:China; D013505:Digestive System Surgical Procedures / Q000009:adverse effects; D017558:Elective Surgical Procedures; D005260:Female; D005440:Fluid Therapy / Q000009:adverse effects; D006801:Humans; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D016343:Monitoring, Intraoperative / Q000295:instrumentation / Q000379:methods*; D011237:Predictive Value of Tests; D020127:Recovery of Function; D012121:Respiration, Artificial; D013318:Stroke Volume; D013997:Time Factors; D014160:Transducers, Pressure; D016896:Treatment Outcome; D014554:Urination