title: Effects of high-intensity and blood flow-restricted low-intensity resistance training on carotid arterial compliance: role of blood pressure during training sessions.
abstract: We examined the effects of high-intensity resistance training (HIT) and low-intensity blood flow-restricted (LI-BFR) resistance training on carotid arterial compliance. Nineteen young men were randomly divided into HIT (n = 9) or LI-BFR (n = 10) groups. The HIT and LI-BFR groups performed 75 and 30 %, respectively, of one-repetition maximum (1-RM) bench press exercise, 3 days per week for 6 weeks. During the training sessions, the LI-BFR group wore elastic cuffs around the most proximal region of both arms. Muscle cross-sectional area (CSA), 1-RM strength, and carotid arterial compliance were measured before and 3 days after the final training session. Acute changes in systolic arterial pressure (SAP), plasma endothelin-1 (ET-1), nitrite/nitrate (NOx), and noradrenalin concentrations were also measured during and after a bout of training session. The training led to significant increases (P < 0.01) in bench press 1-RM and arm and chest muscle CSA in the two training groups. Carotid arterial compliance decreased significantly (P < 0.05) in the HIT group, but not in the LI-BFR group. There was a significant correlation (r = -0.533, P < 0.05) between the change in carotid arterial compliance and the acute change in SAP during training sessions; however, ET-1 and NOx did not correlate with carotid arterial compliance. Our results suggest that muscle CSA and strength increased following 6 weeks of both HIT and LI-BFR training. However, carotid arterial compliance decreased in only the HIT group, and the changes were correlated with SAP elevations during exercise sessions.
authors.affiliation: Graduate School of Frontier Sciences, University of Tokyo, Kashiwa, Chiba, Japan. ozaki.hayao@gmail.com
authors.forename: Hayao
authors.initials: H
authors.lastname: Ozaki
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Yasuda
authors.forename: Riki
authors.initials: R
authors.lastname: Ogasawara
authors.forename: Mikako
authors.initials: M
authors.lastname: Sakamaki-Sunaga
authors.forename: Hisashi
authors.initials: H
authors.lastname: Naito
authors.forename: Takashi
authors.initials: T
authors.lastname: Abe
mesh_terms: D000328:Adult; D062186:Arterial Pressure / Q000502:physiology*; D001783:Blood Flow Velocity; D002339:Carotid Arteries / Q000502:physiology*; D006801:Humans; D008297:Male; D010807:Physical Endurance / Q000502:physiology*; D005082:Physical Exertion / Q000502:physiology*; D055070:Resistance Training / Q000379:methods*; D014655:Vascular Resistance / Q000502:physiology*; D055815:Young Adult