title: [Intracellular gaseous messengers, nitric oxide, carbon monoxide and hydrogen sulfide participate in apoptosis regulation].
abstract: In this paper, participation of gases, nitric oxide, carbon monoxide and hydrogen sulfide, in cell apoptosis regulation has been analyzed according to the literature data and our own findings. Different mechanisms of nitric oxide influence on apoptotic reaction including modulation of transcription factors activity and increase in mitochondrion membrane permeabilisation are described. Brief description of the generation and signal transduction pathways of carbon monoxide is presented. Pro- and antiapoptotic mechanisms of hydrogen sulfide influence on cell fate are analyzed.
authors.forename: N V
authors.initials: NV
authors.lastname: Riazantseva
authors.forename: E G
authors.initials: EG
authors.lastname: Starikova
authors.forename: L A
authors.initials: LA
authors.lastname: Tashireva
authors.forename: E A
authors.initials: EA
authors.lastname: Stepovaia
authors.forename: Iu V
authors.initials: IuV
authors.lastname: Starikov
authors.forename: I A
authors.initials: IA
authors.lastname: Osikhov
authors.forename: V V
authors.initials: VV
authors.lastname: Novitskiĭ
mesh_terms: D000818:Animals; D017209:Apoptosis; D051017:Apoptosis Regulatory Proteins / Q000235:genetics / Q000378:metabolism; D002248:Carbon Monoxide / Q000378:metabolism*; D002478:Cells, Cultured; D005786:Gene Expression Regulation; D006418:Heme / Q000378:metabolism; D006801:Humans; D006862:Hydrogen Sulfide / Q000378:metabolism*; D051379:Mice; D009569:Nitric Oxide / Q000378:metabolism*; D015290:Second Messenger Systems / Q000502:physiology*; D014157:Transcription Factors / Q000235:genetics / Q000378:metabolism
chemical_list: D051017:Apoptosis Regulatory Proteins; D014157:Transcription Factors; D009569:Nitric Oxide; D006418:Heme; D002248:Carbon Monoxide; D006862:Hydrogen Sulfide