title: Validation of transcatheter left ventricular electromechanical mapping for assessment of cardiac function and targeted transendocardial injection in a porcine ischemia-reperfusion model.
abstract: Ischemic heart disease, despite advances in treatment, remains the major cause of mortality worldwide. NOGA 3D left ventricular electromechanical mapping allows accurate determination of cardiac function and precise identification of sites of injury. In a porcine model of ischemia-reperfusion injury, we validate the use of the NOGA mapping system for assessment of cardiac function along with the Myostar injection catheter for directed delivery of therapeutics to localized target sites in the setting of acute myocardial injury.
authors.affiliation: Cardiovascular Research Center, Temple University School of Medicine Philadelphia, PA, USA.
authors.forename: Sharven
authors.initials: S
authors.lastname: Taghavi
authors.forename: Jason M
authors.initials: JM
authors.lastname: Duran
authors.forename: Remus M
authors.initials: RM
authors.lastname: Berretta
authors.forename: Catherine A
authors.initials: CA
authors.lastname: Makarewich
authors.forename: Foram
authors.initials: F
authors.lastname: Udeshi
authors.forename: Thomas E
authors.initials: TE
authors.lastname: Sharp
authors.forename: Hajime
authors.initials: H
authors.lastname: Kubo
authors.forename: Steven R
authors.initials: SR
authors.lastname: Houser
authors.forename: Jon C
authors.initials: JC
authors.lastname: George