title: The promise of immunisation against rotavirus.
abstract: Infectious diarrhoea is a common disease of childhood. It is estimated to be responsible for over 1.3 million deaths per year, predominantly in resource-poor countries. In wealthy nations, it causes significant morbidity, healthcare burden and associated cost. In both scenarios, the most common cause is rotavirus. This article reviews the experience of primary prevention of rotavirus disease through immunisation and considers the case for extending vaccine use further in Europe and globally.
authors.affiliation: Bristol Royal Hospital for Children, University Hospitals Bristol NHS Foundation Trust, Bristol, UK.
authors.forename: Robin D
authors.initials: RD
authors.lastname: Marlow
authors.forename: Adam
authors.initials: A
authors.lastname: Finn
mesh_terms: D002662:Child Health Services / Q000706:statistics & numerical data*; D002675:Child, Preschool; D019049:Developed Countries / Q000706:statistics & numerical data; D003906:Developing Countries / Q000706:statistics & numerical data; D014943:Global Health / Q000706:statistics & numerical data; D006801:Humans; D017589:Immunization Programs / Q000706:statistics & numerical data; D007223:Infant; D012401:Rotavirus / Q000276:immunology*; D012400:Rotavirus Infections / Q000191:economics / Q000517:prevention & control*; D022243:Rotavirus Vaccines / Q000008:administration & dosage* / Q000009:adverse effects / Q000191:economics
chemical_list: D022243:Rotavirus Vaccines