title: 2-[6-(4-Bromo-phen-yl)imidazo[2,1-b][1,3]thia-zol-3-yl]-N-[8-(4-hy-droxy-phen-yl)-2-methyl-3-oxo-1-thia-4-aza-spiro-[4.5]decan-4-yl]acetamide ethanol disolvate.
abstract: In the title compound, C(28)H(27)BrN(4)O(3)S(2)·2C(2)H(6)O, the cyclo-hexane ring adopts a chair conformation. The imidazo[2,1-b][1,3]thia-zole ring system is essentially planar with a dihedral angle of 1.1 (2)° between the thia-zole and imidazole rings. The mean plane of this ring system makes dihedral angles of 8.11 (16) and 79.43 (17)°, respectively, with the bromo- and hy-droxy-substituted benzene rings. In the 5-methyl-1,3-thia-zolidin-4-one group, the S atom, the methyl group and the ring C atoms bonded to them are disordered over two sets of sites with refined occupancies of 0.610 (19) and 0.390 (19). The crystal structure features N-H⋯O, O-H⋯O, O-H⋯N and C-H⋯O hydrogen bonds and C-H⋯π inter-actions. Furthermore, two weak π-π stacking inter-actions [centroid-centroid distances = 3.967 (3) and 3.892 (2) Å] are also observed.
authors.forename: Mehmet
authors.initials: M
authors.lastname: Akkurt
authors.forename: Elif
authors.initials: E
authors.lastname: Gürsoy
authors.forename: Nuray Ulusoy
authors.initials: NU
authors.lastname: Güzeldemirci
authors.forename: Sevim
authors.initials: S
authors.lastname: Türktekin-Çelikesir
authors.forename: Muhammad Nawaz
authors.initials: MN
authors.lastname: Tahir