title: Comparison of noninvasive continuous arterial waveform analysis (Nexfin) with transthoracic Doppler echocardiography for monitoring of cardiac output.
abstract: OBJECTIVE
  To compare the Nexfin cardiac output (CO) with the CO obtained from transthoracic Doppler echocardiography (TTE) during routine cardiac function screening.
  
  
  METHODS
  Observational clinical study.
  
  
  METHODS
  Echocardiography laboratory.
  
  
  METHODS
  40 ASA physical status 1 and 2 patients scheduled for routine TTE examination.
  
  
  METHODS
  None.
  
  
  RESULTS
  In 40 patients scheduled for routine TTE examination, we obtained simultaneous CO measurements with Doppler ultrasound and derived from Nexfin blood pressure measurements. Correlation and level of agreement between Nexfin and TTE were analyzed using Pearson correlation coefficient and Bland-Altman plots. The Pearson correlation coefficient for Nexfin versus TTE was 0.68 (CI: 0.46 - 0.82, P < 0.0001). Bland-Altman analysis showed a bias of 0.51 ± 1.1 L/min and limits of agreement of -1.6 to 2.6 L/min, with a percentage error of 39%.
  
  
  CONCLUSIONS
  Considering limits of precision of CO measurements with Doppler echocardiography (± 30%), the agreement between noninvasive CO measurement with the Nexfin and TTE is reasonable.
authors.affiliation: Department of Anesthesiology, Institute for Cardiovascular Research, VU University Medical Center, 1081 HV, Amsterdam, The Netherlands.
authors.forename: Anna G E
authors.initials: AG
authors.lastname: van der Spoel
authors.forename: Albertus J
authors.initials: AJ
authors.lastname: Voogel
authors.forename: Anja
authors.initials: A
authors.lastname: Folkers
authors.forename: Christa
authors.initials: C
authors.lastname: Boer
authors.forename: R Arthur
authors.initials: RA
authors.lastname: Bouwman
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001795:Blood Pressure Determination / Q000379:methods; D015924:Blood Pressure Monitors; D001916:Brachial Artery / Q000502:physiology; D002302:Cardiac Output / Q000502:physiology*; D015150:Echocardiography, Doppler; D017548:Echocardiography, Transesophageal / Q000379:methods; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008991:Monitoring, Physiologic / Q000295:instrumentation / Q000379:methods; D015203:Reproducibility of Results