title: One-pot primary aminomethylation of aryl and heteroaryl halides with sodium phthalimidomethyltrifluoroborate.
abstract: A one-pot primary aminomethylation of aryl halides, triflates, mesylates, and tosylates via Suzuki-Miyaura cross-coupling reactions with sodium phthalimidomethyltrifluoroborate followed by deamidation with ethylenediamine is reported.
authors.affiliation: Graduate School of Pharmaceutical Sciences, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.
authors.forename: Norio
authors.initials: N
authors.lastname: Murai
authors.forename: Masayuki
authors.initials: M
authors.lastname: Miyano
authors.forename: Masahiro
authors.initials: M
authors.lastname: Yonaga
authors.forename: Keigo
authors.initials: K
authors.lastname: Tanaka
mesh_terms: D001881:Borates / Q000737:chemistry*; D002384:Catalysis; D005029:Ethylenediamines / Q000737:chemistry*; D006846:Hydrocarbons, Halogenated / Q000737:chemistry*; D008698:Mesylates / Q000737:chemistry*; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*; D012964:Sodium / Q000737:chemistry; D014105:Tosyl Compounds / Q000737:chemistry*
chemical_list: D001881:Borates; D005029:Ethylenediamines; D006846:Hydrocarbons, Halogenated; D008698:Mesylates; D014105:Tosyl Compounds; C045880:methanesulfonic acid; D010165:Palladium; D012964:Sodium