title: Iron-catalyzed 2-arylbenzoxazole formation from o-nitrophenols and benzylic alcohols.
abstract: The iron-catalyzed 2-arylbenzoxazole formation from o-nitrophenols and benzylic alcohols using hydrogen transfer is described. Various 2-arylbenzoxazoles were selectively obtained in good to excellent yields. The reaction tolerated a wide range of functionalities. The alcohol oxidation, nitro reduction, condensation, and dehydrogenation were realized in a cascade without external reducing reagent and oxidant.
authors.affiliation: Key Laboratory of Environmentally Friendly Chemistry and Application of Ministry of Education, College of Chemistry, Xiangtan University, Xiangtan 411105, China.
authors.forename: Mingyue
authors.initials: M
authors.lastname: Wu
authors.forename: Xiong
authors.initials: X
authors.lastname: Hu
authors.forename: Juan
authors.initials: J
authors.lastname: Liu
authors.forename: Yunfeng
authors.initials: Y
authors.lastname: Liao
authors.forename: Guo-Jun
authors.initials: GJ
authors.lastname: Deng
mesh_terms: D001583:Benzoxazoles / Q000138:chemical synthesis* / Q000737:chemistry; D001592:Benzyl Alcohols / Q000737:chemistry*; D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D003500:Cyclization; D007501:Iron / Q000737:chemistry*; D015394:Molecular Structure; D009596:Nitrophenols / Q000737:chemistry*; D010084:Oxidation-Reduction
chemical_list: D001583:Benzoxazoles; D001592:Benzyl Alcohols; D009596:Nitrophenols; D007501:Iron