title: The future of molecular diagnostics for drug-resistant tuberculosis.
abstract: The last decade has seen significant advances in tuberculosis diagnostics and drug susceptibility testing (DST). During the same time period the prevalence of drug-resistant tuberculosis has increased and therefore it has become critical to understand DST for medications used to treat multidrug-resistant and extensively drug-resistant tuberculosis. This review describes recent molecular diagnostic advances for DST. Recommendations are provided for clinicians interpreting molecular DST and we describe potential opportunities for the field.
authors.affiliation: Division of Infectious Diseases & International Health, University of Virginia, PO Box 801337, Charlottesville, VA 22908-1337, USA.
authors.forename: Scott K
authors.initials: SK
authors.lastname: Heysell
authors.forename: Eric R
authors.initials: ER
authors.lastname: Houpt
mesh_terms: D000995:Antitubercular Agents / Q000627:therapeutic use; D006801:Humans; D008826:Microbial Sensitivity Tests; D016133:Polymerase Chain Reaction; D018088:Tuberculosis, Multidrug-Resistant / Q000175:diagnosis* / Q000188:drug therapy
chemical_list: D000995:Antitubercular Agents