title: Synthesis, structure-activity relationship and docking studies of substituted aryl thiazolyl phenylsulfonamides as potential protein tyrosine phosphatase 1B inhibitors.
authors.affiliation: Division of Medicinal and Process Chemistry, Council of Scientific and Industrial Research (CSIR), Central Drug Research Institute (CDRI), Chattar Manzil Palace, M G Marg, Lucknow, Uttar Pardesh 226001, India.
authors.forename: Kanika
authors.initials: K
authors.lastname: Varshney
authors.forename: Swati
authors.initials: S
authors.lastname: Gupta
authors.forename: Neha
authors.initials: N
authors.lastname: Rahuja
authors.forename: Arun K
authors.initials: AK
authors.lastname: Rawat
authors.forename: Nagendra
authors.initials: N
authors.lastname: Singh
authors.forename: Akhilesh K
authors.initials: AK
authors.lastname: Tamarkar
authors.forename: Arvind K
authors.initials: AK
authors.lastname: Srivastava
authors.forename: Anil K
authors.initials: AK
authors.lastname: Saxena
mesh_terms: D000818:Animals; D004791:Enzyme Inhibitors / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*; D008958:Models, Molecular; D015394:Molecular Structure; D054562:Protein Tyrosine Phosphatase, Non-Receptor Type 1 / Q000037:antagonists & inhibitors* / Q000378:metabolism; D051381:Rats; D013329:Structure-Activity Relationship; D013449:Sulfonamides / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*; D013844:Thiazoles / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*
chemical_list: D004791:Enzyme Inhibitors; D013449:Sulfonamides; D013844:Thiazoles; D054562:Protein Tyrosine Phosphatase, Non-Receptor Type 1