title: Can cardiac surgery be performed safely on patients with haematological malignancies.
abstract: BACKGROUND
  Surgical strategy in patients with haematological malignancies must be planned and carried out with the specific aim of decreasing postoperative complications. The aim of this study was to present our experience on patients previously diagnosed with haematological malignancies who subsequently underwent cardiac surgery. We include data to assist other surgeons predict factors affecting postoperative morbidity and mortality in this group of patients.
  
  
  METHODS
  Fifteen patients diagnosed with haematological malignancies who had cardiac surgery were retrospectively analysed. Eight patients had chronic lymphocytic leukaemia, six had non-Hodgkin's lymphoma and the rest had chronic myelocytic leukaemia. Coronary artery bypass graft surgery was performed on all of them.
  
  
  RESULTS
  There were no hospital mortalities. The average follow-up period was 35 ± 11 (23-56) months. Three patients required early postoperative re-operation because of excessive bleeding. No mortalities were seen in the early postoperative period. There were five (33%) deaths during the late follow-up period. Three patients were lost due to intracranial bleeding (confirmed by autopsy) in the 16th, 23rd and 38th months after surgery. The remaining two patients had sudden death in the eighth and 55th months from nondetectable causes.
  
  
  CONCLUSIONS
  Cardiac surgery can be performed with acceptable early postoperative outcomes in patients with haematological malignancies. Intracranial bleeding is an important factor contributing to late mortality and patient selection and risk stratification are crucial to improving surgical benefits.
authors.affiliation: Department of Cardiovascular Surgery, Gulhane Military Medical Academy, Etlik, Ankara, Turkey.
authors.forename: A
authors.initials: A
authors.lastname: Guler
authors.forename: M A
authors.initials: MA
authors.lastname: Sahin
authors.forename: F
authors.initials: F
authors.lastname: Cingoz
authors.forename: E
authors.initials: E
authors.lastname: Ozal
authors.forename: U
authors.initials: U
authors.lastname: Demirkilic
authors.forename: M
authors.initials: M
authors.lastname: Arslan
mesh_terms: D000328:Adult; D000368:Aged; D006348:Cardiac Surgical Procedures / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006331:Heart Diseases / Q000150:complications / Q000401:mortality / Q000601:surgery*; D019337:Hematologic Neoplasms / Q000150:complications* / Q000401:mortality; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000453:epidemiology* / Q000209:etiology; D012189:Retrospective Studies; D012307:Risk Factors; D015996:Survival Rate / Q000639:trends; D016896:Treatment Outcome; D014421:Turkey / Q000453:epidemiology