title: Formal asymmetric enone aminohydroxylation: organocatalytic one-pot synthesis of 4,5-disubstituted oxazolidinones.
abstract: A formal asymmetric organocatalytic aminohydroxylation reaction of enones has been achieved via an aziridination-double S(N)2 sequence. As a part of the reaction design, the generated amino alcohol products are isolated as the corresponding oxazolidinones in good yields and excellent stereoselectivities.
authors.affiliation: Center for Catalysis, Aarhus University, Langelandsgade 140, DK-8000 Aarhus C, Denmark.
authors.forename: David Cruz
authors.initials: DC
authors.lastname: Cruz
authors.forename: Pedro A
authors.initials: PA
authors.lastname: Sánchez-Murcia
authors.forename: Karl Anker
authors.initials: KA
authors.lastname: Jørgensen
mesh_terms: D002384:Catalysis; D018360:Crystallography, X-Ray; D006900:Hydroxylation; D007659:Ketones / Q000737:chemistry*; D008958:Models, Molecular; D015394:Molecular Structure; D023303:Oxazolidinones / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D007659:Ketones; D023303:Oxazolidinones