title: Antifreeze on a freezing morning: ethylene glycol poisoning in a 2-year-old.
abstract: This case report describes the presentation and management of a 2-year-old child who ingested a potentially fatal amount of ethylene glycol (EG). There are few published cases worldwide of EG poisoning in children managed with fomepizole. All cases described in the literature were managed in a paediatric intensive care unit. In this case, the child presented irritable, pale and confused with high anion gap metabolic acidosis. As there were no paediatric intensive care beds available in the region, the child was successfully managed in a high dependency area in our district general hospital. The child fully recovered and was discharged home in 7 days. The authors believe that multi-disciplinary team management and the use of fomepizole contributed to the positive outcome and this case raised many useful learning points.
authors.affiliation: Paediatrics Department, North Middlesex Hospital, London, UK. gaylehann@yahoo.com
authors.forename: Gayle
authors.initials: G
authors.lastname: Hann
authors.forename: Dana
authors.initials: D
authors.lastname: Duncan
authors.forename: Gopakumar
authors.initials: G
authors.lastname: Sudhir
authors.forename: Peter
authors.initials: P
authors.lastname: West
authors.forename: Dalbir
authors.initials: D
authors.lastname: Sohi
mesh_terms: D000931:Antidotes / Q000008:administration & dosage; D002675:Child, Preschool; D019855:Ethylene Glycol / Q000506:poisoning*; D000077604:Fomepizole; D006801:Humans; D008297:Male; D011041:Poisoning / Q000175:diagnosis* / Q000628:therapy*; D011720:Pyrazoles / Q000008:administration & dosage
chemical_list: D000931:Antidotes; D011720:Pyrazoles; D000077604:Fomepizole; D019855:Ethylene Glycol