title: Persistent hypereosinophilia with Wells syndrome.
abstract: Since Wells and Smith first described cases of eosinophilic cellulitis (Wells syndrome; WS) in 1979, it has been noted that some but not all patients with WS present with eosinophilia. In the face of idiopathic persistent eosinophilia patients will also then fall within the hypereosinophilic syndrome (HES), which represents a multifarious spectrum of disorders of varying severity, causes and outcomes. In this article we propose that patients who present within the HES spectrum with cutaneous findings of WS and with no extracutaneous disease be classified as having 'persistent hypereosinophilia with Wells syndrome' (PHEWS).
authors.affiliation: Department of Dermatology, Solihull Hospital, Heart of England NHS Foundation Trust, Birmingham, UK. jbpowell@doctors.org.uk
authors.forename: J
authors.initials: J
authors.lastname: Powell
authors.forename: A
authors.initials: A
authors.lastname: Salim
authors.forename: R
authors.initials: R
authors.lastname: Muc
authors.forename: P
authors.initials: P
authors.lastname: Colloby
authors.forename: M R
authors.initials: MR
authors.lastname: Kaur
mesh_terms: D002481:Cellulitis / Q000145:classification / Q000473:pathology*; D003937:Diagnosis, Differential; D004802:Eosinophilia / Q000145:classification / Q000473:pathology*; D005260:Female; D006801:Humans; D017681:Hypereosinophilic Syndrome / Q000145:classification / Q000473:pathology*; D008875:Middle Aged