title: Identifying patients at risk of severe Clostridium difficile-associated disease.
abstract: Clostridium difficile infection is responsible for a wide spectrum of clinical presentations, ranging from mild diarrhoea to fatal toxic colitis. This article reviews factors which may identify individuals who are at high risk of severe C. difficile-associated disease, and aims to help clinicians predict patients at risk of severe disease.
authors.affiliation: Department of Medicine, Lister Hospital, Stevenage, Hertfordshire, UK.
authors.forename: Valerie A
authors.initials: VA
authors.lastname: Potter
authors.forename: Aloysious
authors.initials: A
authors.lastname: Aravinthan
mesh_terms: D000367:Age Factors; D000900:Anti-Bacterial Agents / Q000009:adverse effects; D016360:Clostridioides difficile; D015897:Comorbidity; D016099:Endoscopy, Gastrointestinal / Q000009:adverse effects; D004761:Enterocolitis, Pseudomembranous / Q000453:epidemiology* / Q000209:etiology; D004777:Environment; D005765:Gastrointestinal Agents / Q000009:adverse effects; D006801:Humans; D007441:Intubation, Gastrointestinal / Q000009:adverse effects; D018570:Risk Assessment; D012737:Sex Factors
chemical_list: D000900:Anti-Bacterial Agents; D005765:Gastrointestinal Agents