title: Significant head motion can cause either hypermetabolic or hypometabolic cerebral activity on 18F-FDG PET/CT.
abstract: We report 2 separate cases with significant head motion causing apparent hypometabolic and hypermetabolic cerebral activity on FDG PET/CT. Case 1 is a 57-year-old man with facial numbness status post chemotherapy for mantle cell lymphoma. Restaging attenuation-corrected PET showed increased left frontal region activity, whereas nonattenuation-corrected PET demonstrated evidence of patient motion with normal physiologic left frontal cortical activity. Case 2 is a 78-year-old man with history of malignant melanoma. Attenuation-corrected PET/CT demonstrated diffusely decreased activity in the left cerebral hemisphere, whereas nonattenuation-corrected PET showed significant head motion with intact cortical activity.
authors.affiliation: PET Imaging Science Center, Division of Nuclear Medicine, Department of Radiology, Keck School of Medicine University of Southern California, Los Angeles, CA, USA. linhho@usc.edu
authors.forename: Linh Thuy
authors.initials: LT
authors.lastname: Ho
authors.forename: Vincent
authors.initials: V
authors.lastname: Ngo
authors.forename: Harvard
authors.initials: H
authors.lastname: Vuu
authors.forename: Richard
authors.initials: R
authors.lastname: Montion
mesh_terms: D000368:Aged; D001921:Brain / Q000000981:diagnostic imaging* / Q000378:metabolism*; D005188:False Negative Reactions; D005189:False Positive Reactions; D019788:Fluorodeoxyglucose F18 / Q000378:metabolism*; D019416:Head Movements; D006801:Humans; D006987:Hypesthesia / Q000000981:diagnostic imaging / Q000378:metabolism / Q000503:physiopathology; D008297:Male; D008545:Melanoma / Q000000981:diagnostic imaging / Q000378:metabolism / Q000503:physiopathology; D008875:Middle Aged; D064847:Multimodal Imaging; D049268:Positron-Emission Tomography; D014057:Tomography, X-Ray Computed
chemical_list: D019788:Fluorodeoxyglucose F18