title: [Diagnostic biomarkers in inflammatory bowel disease].
abstract: Inflammatory bowel diseases (IBD), which includes ulcerative colitis and Crohn's disease, are chronic intestinal disorders of unknown etiology. The diagnosis of IBD is based upon clinical history, endoscopic, and histological findings; however, accurate diagnosis can still be difficult with these current methodologies. Recent advances in molecular techniques in proteomics and genetic analysis have driven the discovery of novel IBD biomarkers and genetic susceptibility factors that may facilitate the diagnosis of IBD. In the future, biomarkers will play a key role in the diagnosis of IBD and the development of individual courses of treatment.
authors.affiliation: Department of Pathology, Keck School of Medicine, University of Southern California.
authors.forename: Shuji
authors.initials: S
authors.lastname: Kanmura
authors.forename: Toshio
authors.initials: T
authors.lastname: Sakiyama
authors.forename: Hirofumi
authors.initials: H
authors.lastname: Uto
authors.forename: Hirohito
authors.initials: H
authors.lastname: Tsubouchi
mesh_terms: D000818:Animals; D015415:Biomarkers / Q000097:blood*; D020022:Genetic Predisposition to Disease; D023281:Genomics; D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000175:diagnosis* / Q000235:genetics; D051379:Mice
chemical_list: D015415:Biomarkers