title: Birdshot retinochoroidopathy masquerading as intraocular lymphoma.
abstract: We present a case of a patient with bilateral posterior uveitis HLA-A29 positive, masquerading intraocular lymphoma. A 43 year-old woman presented with bilateral vitritis and chorioretinal lesions compatible with "birdshot lesions". The patient was initially diagnosed with birdshot retinochoroidopathy and later on, during follow up, the occurrence of neurologic involvement and the lack of response to systemic immunosuppression led us to re-evaluate the diagnosis. A definite diagnosis of intraocular lymphoma with central nervous system involvement was made. This case is presented to highlight the importance of careful follow-up of patients with chronic uveitis and re-evaluation of systemic symptoms and signs, in particular when ocular findings are highly suggestive for masquerade syndrome.
authors.forename: Elisabetta
authors.initials: E
authors.lastname: Miserocchi
authors.forename: Giulio
authors.initials: G
authors.lastname: Modorati
authors.forename: Umberto
authors.initials: U
authors.lastname: De Benedetto
authors.forename: Annalisa
authors.initials: A
authors.lastname: Colucci
authors.forename: Francesco
authors.initials: F
authors.lastname: Bandello
mesh_terms: D000328:Adult; D018941:Antigens, CD19 / Q000032:analysis; D018951:Antigens, CD20 / Q000032:analysis; D000080365:Birdshot Chorioretinopathy; D016543:Central Nervous System Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000532:radiotherapy; D002825:Chorioretinitis / Q000175:diagnosis* / Q000188:drug therapy; D016572:Cyclosporine / Q000627:therapeutic use; D005134:Eye Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000532:radiotherapy; D017809:Fatal Outcome; D005260:Female; D015234:HLA-A Antigens / Q000032:analysis; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D016403:Lymphoma, Large B-Cell, Diffuse / Q000175:diagnosis* / Q000188:drug therapy / Q000532:radiotherapy; D008271:Mycetoma / Q000175:diagnosis; D011241:Prednisone / Q000627:therapeutic use; D014792:Visual Acuity
chemical_list: D018941:Antigens, CD19; D018951:Antigens, CD20; D015234:HLA-A Antigens; C035524:HLA-A29 antigen; D007166:Immunosuppressive Agents; D016572:Cyclosporine; D011241:Prednisone