title: Severe coronary artery disease in Chinese patients with abdominal aortic aneurysm: prevalence and impact on operative mortality.
abstract: BACKGROUND
  Little is known about the prognosis of coronary artery disease (CAD) in Chinese patients with abdominal aortic aneurysm (AAA). The aim of this study was to evaluate the predictors of in-hospital all-cause mortality of severe CAD in Chinese patients who were hospitalized for AAAs.
  
  
  METHODS
  From January 2003 to August 2009, 368 patients were operated on for AAAs. The clinical characteristics were retrospectively collected. The primary outcome was the in-hospital all-cause mortality. The clinical risk factors were subjected to a multivariate analysis to determine the predictors of in-hospital all-cause mortality.
  
  
  RESULTS
  During their hospitalization, 23% (85/368) of the patients underwent coronary angiography, which revealed significant lesions in 93% (79/85) of the patients. In 25 cases, coronary artery bypass grafting (CABG) was performed before the AAA repair and in 16 cases of percutaneous coronary intervention (PCI) was performed. Ten patients with AAA alone died before discharge, and eight patients diagnosed with AAA combined with CAD died. There was no statistical difference in the postoperative death between the two groups. The logistic analysis showed that age > 70 years and CAD (vessels ≥ 2) were the significant factors in predicting the adverse clinical outcome.
  
  
  CONCLUSIONS
  The prevalence of severe CAD in Chinese patients with AAAs seemed lower than those that were reported. Myocardial evaluation and subsequent revascularization before AAA surgery could improve the clinical outcome for these patients who have severe CAD.
authors.affiliation: Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, China.
authors.forename: Tao
authors.initials: T
authors.lastname: Sun
authors.forename: Yu-tong
authors.initials: YT
authors.lastname: Cheng
authors.forename: Hong-ju
authors.initials: HJ
authors.lastname: Zhang
authors.forename: Shun-hua
authors.initials: SH
authors.lastname: Chen
authors.forename: Dong-hua
authors.initials: DH
authors.lastname: Zhang
authors.forename: Ji
authors.initials: J
authors.lastname: Huang
authors.forename: Jing-mei
authors.initials: JM
authors.lastname: Zhang
authors.forename: Zhi-zhong
authors.initials: ZZ
authors.lastname: Li
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D017544:Aortic Aneurysm, Abdominal / Q000150:complications / Q000401:mortality* / Q000601:surgery; D002681:China / Q000453:epidemiology; D003324:Coronary Artery Disease / Q000453:epidemiology / Q000401:mortality* / Q000601:surgery; D005260:Female; D017052:Hospital Mortality; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D015995:Prevalence; D012189:Retrospective Studies