title: Diagnostic role of endoscopic ultrasonography-guided fine needle aspiration of gallbladder lesions.
abstract: OBJECTIVE
  Endoscopic ultrasonography-guided fine needle aspiration (EUS-FNA) is a well-established diagnostic technique for examining various organs of the gastrointestinal tract and pancreas, but little is known about its use in the diagnostic work-up of GB lesions. The objective of this retrospective study was to evaluate the efficacy of EUS-FNA of GB lesions.
  
  
  METHODS
  Twenty-eight patients who underwent EUS-FNA for evaluation of GB lesions were enrolled. The pathological results and complications were assessed.
  
  
  RESULTS
  EUS-FNA of GB was performed in 13 patients and that of enlarged lymph nodes was done in 18. Of the 13 GB lesions sampled by EUS-FNA, 10 were diagnosed as malignant and 3 were negative for malignant cells. Of the latter 3, two were false negatives for malignancy. All 14 metastatic lymphadenopathy cases were diagnosed with EUS-FNA of lymph nodes. EUS-FNA could differentiate adenocarcinomas and other malignant diseases. Cholecystitis occurred in one patient after EUS-FNA of the GB.
  
  
  CONCLUSIONS
  EUS-FNA is a feasible, safe and reliable method for obtaining samples from GB lesions. EUS-FNA of lymph nodes is complementary to EUS-FNA of the GB and provides nodal stage as well as histological diagnosis.
authors.affiliation: Department of Internal Medicine, Asan Medical Center, Univeristy of Ulsan College of Medicine, Seoul, Korea.
authors.forename: Hong Jun
authors.initials: HJ
authors.lastname: Kim
authors.forename: Sung-Koo
authors.initials: SK
authors.lastname: Lee
authors.forename: Ji Woong
authors.initials: JW
authors.lastname: Jang
authors.forename: Tae Gyoon
authors.initials: TG
authors.lastname: Kim
authors.forename: Choong Heon
authors.initials: CH
authors.lastname: Ryu
authors.forename: Do Hyun
authors.initials: DH
authors.lastname: Park
authors.forename: Sang Soo
authors.initials: SS
authors.lastname: Lee
authors.forename: Dong Wan
authors.initials: DW
authors.lastname: Seo
authors.forename: Myung-Hwan
authors.initials: MH
authors.lastname: Kim
mesh_terms: D000230:Adenocarcinoma / Q000556:secondary*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002764:Cholecystitis / Q000209:etiology; D061765:Endoscopic Ultrasound-Guided Fine Needle Aspiration / Q000009:adverse effects; D005188:False Negative Reactions; D005260:Female; D005704:Gallbladder / Q000473:pathology*; D005705:Gallbladder Diseases / Q000473:pathology*; D005706:Gallbladder Neoplasms / Q000473:pathology*; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology*; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D011379:Prognosis; D056910:Republic of Korea; D012189:Retrospective Studies