title: The impact of immediate breast reconstruction on post-mastectomy lymphedema in patients undergoing modified radical mastectomy.
abstract: The aim of this study was to assess the impact of immediate breast reconstruction (IBR) with autologous tissue on the development of post-mastectomy lymphedema in patients undergoing modified radical mastectomy (MRM). A retrospective chart review was performed for early-stage breast cancer patients who underwent MRM between January 2001 and December 2009. Patients were categorized into two groups based on whether or not they underwent IBR. The incidence of lymphedema was assessed and compared. A total of 712 patients underwent MRM, which included 117 patients undergoing IRB. There were no significant differences between two groups except for a lower body mass index in the reconstruction group. Comparing the incidence of lymphedema using multivariate logistic regression analysis, the reconstruction group had a significantly lower incidence of lymphedema (p-value = 0.023). Breast cancer patients who underwent MRM with IBR had a significantly lower incidence of lymphedema than those in the non-reconstruction group.
authors.affiliation: Department of Plastic Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Ilwon-dong 50, Kangnam-ku, Seoul 135-710, Republic of Korea.
authors.forename: Kyeong-Tae
authors.initials: KT
authors.lastname: Lee
authors.forename: Goo-Hyun
authors.initials: GH
authors.lastname: Mun
authors.forename: So-Young
authors.initials: SY
authors.lastname: Lim
authors.forename: Jai-Kyong
authors.initials: JK
authors.lastname: Pyon
authors.forename: Kap-Sung
authors.initials: KS
authors.lastname: Oh
authors.forename: Sa-Ik
authors.initials: SI
authors.lastname: Bang
mesh_terms: D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D016015:Logistic Models; D008209:Lymphedema / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control*; D016462:Mammaplasty / Q000379:methods*; D015411:Mastectomy, Modified Radical; D008875:Middle Aged; D015999:Multivariate Analysis; D011183:Postoperative Complications / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control*; D012189:Retrospective Studies; D013524:Surgical Flaps; D013997:Time Factors; D016896:Treatment Outcome