title: Microwave accelerated Glaser-Hay macrocyclizations at high concentrations.
abstract: Efficient macrocyclization can be conducted at high concentrations employing microwave irradiation and a phase separation strategy. The rate of the Glaser-Hay macrocyclization is accelerated using microwave irradiation and reaction times decreased from 48 h to 1-6 h, depending on the nature of the substrate. Macrocyclization concentrations could be increased up to 0.1 M compared to traditional concentrations (0.2 mM).
authors.affiliation: Département de Chimie, Centre for Green Chemistry and Catalysis, Université de Montréal, CP 6128 Station Downtown, Montréal, Québec, CanadaH3C 3J7.  shawn.collins@umontreal.ca.
authors.forename: Anne-Catherine
authors.initials: AC
authors.lastname: Bédard
authors.forename: Shawn K
authors.initials: SK
authors.lastname: Collins