title: Perineal rectosigmoidectomy for primary and recurrent rectal prolapse:  are the results comparable the second time?
abstract: BACKGROUND
  The surgical approach to recurrent full-thickness rectal prolapse after perineal rectosigmoidectomy is complicated by recurrent prolapse. The majority of patients who undergo perineal rectosigmoidectomy are elderly with comorbidities. Therefore, redo perineal rectosigmoidectomy is usually selected to avoid postoperative complications.
  
  
  OBJECTIVE
  This study aimed to evaluate the safety and efficacy of redo perineal rectosigmoidectomy for recurrent full-thickness rectal prolapse.
  
  
  METHODS
  This is a retrospective cohort study.
  
  
  METHODS
  This study was conducted at Cleveland Clinic Florida, from January 2000 to March 2009.
  
  
  METHODS
  One hundred thirty-six patients (129 women), mean age 78 (range, 31-98) years, were included in the study; 113 patients with full-thickness rectal prolapse underwent primary perineal rectosigmoidectomy, and 23 patients with recurrent full-thickness rectal prolapse underwent redo perineal rectosigmoidectomy.
  
  
  METHODS
  All patients underwent perineal rectosigmoidectomy.
  
  
  METHODS
  Perioperative outcomes, recurrence curves, and risk of recurrence were compared between the 2 groups. Age, anterior compartment prolapse, concurrent levatorplasty, and length of bowel resection were analyzed to identify factors potentially influencing recurrence.
  
  
  RESULTS
  Both groups had comparable demographics, BMI, and ASA scores. Operative time, blood loss, length of bowel resection, hospital stay, and follow-up (mean, 42.5 months) were similar in both groups. There was no significant difference in overall complication rates (redo perineal rectosigmoidectomy 17.4% vs. primary perineal rectosigmoidectomy 16.8%; p = 1.00). The recurrence rate for full-thickness rectal prolapse was significantly higher for redo perineal rectosigmoidectomy than primary perineal rectosigmoidectomy (39% vs. 18%; p = 0.007). None of the factors analyzed was associated with recurrence in either group.
  
  
  CONCLUSIONS
  This study was limited by its retrospective methodology. In addition, functional outcomes were not evaluated, because many of the patients died during the follow-up period or were unavailable because of advanced age.
  
  
  CONCLUSIONS
  Redo perineal rectosigmoidectomy is as safe and feasible as primary perineal rectosigmoidectomy in elderly and fragile patients with recurrent full-thickness rectal prolapse. However, the re-recurrence rate for full-thickness rectal prolapse is substantially higher for redo perineal rectosigmoidectomy than primary perineal rectosigmoidectomy.
authors.affiliation: Department of Colorectal Surgery, Cleveland Clinic Florida, Weston, Florida, USA.
authors.forename: Jian-Hua
authors.initials: JH
authors.lastname: Ding
authors.forename: Jorge
authors.initials: J
authors.lastname: Canedo
authors.forename: Seung-Hyun
authors.initials: SH
authors.lastname: Lee
authors.forename: Sudhir N
authors.initials: SN
authors.lastname: Kalaskar
authors.forename: Lester
authors.initials: L
authors.lastname: Rosen
authors.forename: Steven D
authors.initials: SD
authors.lastname: Wexner
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016063:Blood Loss, Surgical / Q000706:statistics & numerical data; D016009:Chi-Square Distribution; D012809:Colon, Sigmoid / Q000601:surgery; D013505:Digestive System Surgical Procedures / Q000379:methods*; D005260:Female; D006801:Humans; D007902:Length of Stay / Q000706:statistics & numerical data; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D016016:Proportional Hazards Models; D012005:Rectal Prolapse / Q000601:surgery*; D012007:Rectum / Q000601:surgery; D012008:Recurrence; D012086:Reoperation; D012189:Retrospective Studies; D018709:Statistics, Nonparametric; D016896:Treatment Outcome