title: Extra-pulmonary primary multidrug-resistant tubercular lymphadenitis in an HIV negative patient.
abstract: A 28-year-old woman without any history of prior antituberculosis treatment presented with cervical lymphadenopathy and a cold abscess near medial end of clavicle of 5 months duration. Pus culture and sensitivity revealed Mycobacterium tuberculosis resistant to rifampicin and isoniazid. Thus she was diagnosed as a case of primary multidrug-resistant tuberculosis and treated with second line drugs according to culture susceptibility pattern. On completion of therapy, patent showed good clinical response. This case highlights the observation that even extra-pulmonary primary multidrug-resistant tuberculosis can be successfully treated with currently available second line drugs.
authors.affiliation: Department of Pulmonary Medicine, CSMMU, Lucknow, India. dr.kantskt@rediffmail.com
authors.forename: Surya
authors.initials: S
authors.lastname: Kant
authors.forename: S
authors.initials: S
authors.lastname: Saheer
authors.forename: Ghulam
authors.initials: G
authors.lastname: Hassan
authors.forename: Jabeed
authors.initials: J
authors.lastname: Parengal
mesh_terms: D000328:Adult; D000995:Antitubercular Agents / Q000627:therapeutic use*; D017291:Clarithromycin / Q000627:therapeutic use; D002991:Clofazimine / Q000627:therapeutic use; D003523:Cycloserine / Q000627:therapeutic use; D003937:Diagnosis, Differential; D004359:Drug Therapy, Combination; D004977:Ethambutol / Q000627:therapeutic use; D005000:Ethionamide / Q000627:therapeutic use; D005260:Female; D018023:HIV Seronegativity; D006801:Humans; D007538:Isoniazid / Q000627:therapeutic use; D007612:Kanamycin / Q000627:therapeutic use; D015242:Ofloxacin / Q000627:therapeutic use; D011718:Pyrazinamide / Q000627:therapeutic use; D012293:Rifampin / Q000627:therapeutic use; D014388:Tuberculosis, Lymph Node / Q000175:diagnosis* / Q000188:drug therapy*; D018088:Tuberculosis, Multidrug-Resistant / Q000175:diagnosis* / Q000188:drug therapy*
chemical_list: D000995:Antitubercular Agents; D011718:Pyrazinamide; D007612:Kanamycin; D004977:Ethambutol; D003523:Cycloserine; D015242:Ofloxacin; D002991:Clofazimine; D017291:Clarithromycin; D005000:Ethionamide; D007538:Isoniazid; D012293:Rifampin