title: Tacrolimus-related hypertrophic cardiomyopathy in an adult cardiac transplant patient.
abstract: Left ventricular hypertrophy associated with the use of tacrolimus is a rare complication of solid organ transplantation in adult recipients. We present a cardiac transplant recipient who developed severe concentric left ventricular hypertrophy with congestive heart failure related to myocardial hypertrophy on tacrolimus. Hypertrophy improved when the drug was discontinued and replaced with sirolimus.
authors.affiliation: Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
authors.forename: Tong
authors.initials: T
authors.lastname: Liu
authors.forename: Yun
authors.initials: Y
authors.lastname: Gao
authors.forename: Yu-long
authors.initials: YL
authors.lastname: Gao
authors.forename: Yu-tong
authors.initials: YT
authors.lastname: Cheng
authors.forename: Su
authors.initials: S
authors.lastname: Wang
authors.forename: Zhi-zhong
authors.initials: ZZ
authors.lastname: Li
authors.forename: Hai-Bo
authors.initials: HB
authors.lastname: Zhang
authors.forename: Xu
authors.initials: X
authors.lastname: Meng
authors.forename: Chang-sheng
authors.initials: CS
authors.lastname: Ma
authors.forename: Jian-zeng
authors.initials: JZ
authors.lastname: Dong
mesh_terms: D000328:Adult; D002312:Cardiomyopathy, Hypertrophic / Q000139:chemically induced* / Q000175:diagnosis*; D005260:Female; D016027:Heart Transplantation / Q000009:adverse effects*; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects* / Q000627:therapeutic use; D008875:Middle Aged; D016559:Tacrolimus / Q000009:adverse effects* / Q000627:therapeutic use
chemical_list: D007166:Immunosuppressive Agents; D016559:Tacrolimus