title: The risk of diagnostic hysteroscopy in women with endometrial cancer.
abstract: OBJECTIVE
  We sought to evaluate whether hysteroscopy in patients with endometrial cancer had an effect on disease stage or mortality.
  
  
  METHODS
  This was a retrospective cohort analysis of data linked between a registry of women diagnosed with endometrial cancer and physician billing data on hysteroscopy.
  
  
  RESULTS
  A 99.8% match rate was obtained. Eighty-five percent of cases had complete data on staging. Of these 1972 cases, 672 (34.1%) had undergone hysteroscopy. There was no difference in stage III disease between the hysteroscopy (7.1%) vs no hysteroscopy (6.5%) group (P = .38). There was also no difference in death rates, 13.2% vs 15.2% (P = .25), or in the proportion of women dying of female genital organ cancer, 46.1% vs 42.1% (P = .53), respectively.
  
  
  CONCLUSIONS
  Hysteroscopy is not associated with a higher rate of stage III disease or mortality. It allows for accurate diagnosis with direct visualization and biopsy, and should be considered a safe diagnostic tool.
authors.affiliation: Department of Obstetrics and Gynecology, Faculty of Medicine, University of Calgary, Calgary, Alberta, Canada.
authors.forename: Jennifer E
authors.initials: JE
authors.lastname: Soucie
authors.forename: Pamela A
authors.initials: PA
authors.lastname: Chu
authors.forename: Sue
authors.initials: S
authors.lastname: Ross
authors.forename: Tom
authors.initials: T
authors.lastname: Snodgrass
authors.forename: Stephen L
authors.initials: SL
authors.lastname: Wood
mesh_terms: D015331:Cohort Studies; D016889:Endometrial Neoplasms / Q000175:diagnosis* / Q000401:mortality / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D015907:Hysteroscopy / Q000009:adverse effects*; D008875:Middle Aged; D009367:Neoplasm Staging; D012042:Registries; D012189:Retrospective Studies; D012306:Risk; D016896:Treatment Outcome