title: Consequences of cooperativity in racemizing supramolecular systems.
abstract: Saluting the sergeant: Phg-BTA (see scheme) cooperatively self-assembles into helical aggregates and shows unprecedented racemization behavior in the presence of base. In thermodynamically controlled conditions, the addition of a small amount of chiral auxiliary to this mixture results in a deracemization reaction and a final enantiomeric excess of 32 %. A theoretical model is presented to understand in detail the results obtained.
authors.affiliation: Institute for Complex Molecular Systems, Laboratory of Macromolecular and Organic Chemistry, Eindhoven University of Technology, P.O. Box 513, 5600 MB Eindhoven, The Netherlands.
authors.forename: Seda
authors.initials: S
authors.lastname: Cantekin
authors.forename: Huub M M
authors.initials: HM
authors.lastname: ten Eikelder
authors.forename: Albert J
authors.initials: AJ
authors.lastname: Markvoort
authors.forename: Martijn A J
authors.initials: MA
authors.lastname: Veld
authors.forename: Peter A
authors.initials: PA
authors.lastname: Korevaar
authors.forename: Mark M
authors.initials: MM
authors.lastname: Green
authors.forename: Anja R A
authors.initials: AR
authors.lastname: Palmans
authors.forename: E W
authors.initials: EW
authors.lastname: Meijer
mesh_terms: D007536:Isomerism; D015394:Molecular Structure; D011108:Polymers / Q000737:chemistry*
chemical_list: D011108:Polymers