title: Decoupling two-dimensional NMR spectroscopy in both dimensions: pure shift NOESY and COSY.
abstract: An increase in the resolving power in 2D NMR spectra is obtained by collapsing 2D signals with multiplet structure into 2D singlets. This resolution gain is achieved by combining 2D experiments with pure shift techniques and covariance processing (see picture). The method should be of value in both manual and automated structure determination.
authors.affiliation: School of Chemistry, University of Manchester, Oxford Road, Manchester, M13 9PL, UK.
authors.forename: Juan A
authors.initials: JA
authors.lastname: Aguilar
authors.forename: Adam A
authors.initials: AA
authors.lastname: Colbourne
authors.forename: Julia
authors.initials: J
authors.lastname: Cassani
authors.forename: Mathias
authors.initials: M
authors.lastname: Nilsson
authors.forename: Gareth A
authors.initials: GA
authors.lastname: Morris
mesh_terms: D017291:Clarithromycin / Q000737:chemistry; D044950:Flavanones / Q000737:chemistry; D006569:Hesperidin / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D015394:Molecular Structure
chemical_list: D044950:Flavanones; D006569:Hesperidin; D017291:Clarithromycin; C005274:naringin