title: Effects of repeated bouts of supramaximal exercise on plasma adiponectin, interleukin-6, and tumor necrosis factor-α levels in sedentary men.
abstract: The objective of the study was to determine the effects of repeated bouts of supramaximal exercise on plasma adiponectin, interleukin (IL)-6 and tumor necrosis factor (TNF)-α levels in sedentary men. Fourteen healthy, nonsmoking, and sedentary men aged between 18.4 and 21.4 years participated in the study. All the subjects performed 5 Wingate tests (WTs) with 75 g per kilogram body weight load with 2-minute intervals between the tests. Blood samples were collected at preexercise, immediately after, 15 and 60 minutes after the fifth WT. Serum and plasma samples were stored at -80°C until the time of analysis for myoglobin, adiponectin, IL-6, and TNF-α. Plasma adiponectin levels decreased, whereas IL-6 levels increased postexercise compared with that preexercise. The TNF-α levels were not changed with supramaximal exercise. In conclusion, repeated bouts of supramaximal exercise cause an inflammatory response in exercised muscle and increase in plasma IL-6 levels and decrease in adiponectin concentrations.
authors.affiliation: Department of Physiology, Meram Faculty of Medicine, Selcuk University, Konya, Turkey.
authors.forename: Hakk
authors.initials: H
authors.lastname: Gökbel
authors.forename: Nilsel
authors.initials: N
authors.lastname: Okudan
authors.forename: Ibrahim
authors.initials: I
authors.lastname: Gül
authors.forename: Muaz
authors.initials: M
authors.lastname: Belviranli
authors.forename: Hasan S
authors.initials: HS
authors.lastname: Gergerlioğlu
authors.forename: Mustafa K
authors.initials: MK
authors.lastname: Başaral
mesh_terms: D052242:Adiponectin / Q000097:blood*; D000293:Adolescent; D015444:Exercise / Q000502:physiology*; D005080:Exercise Test; D006801:Humans; D015850:Interleukin-6 / Q000097:blood*; D008297:Male; D057185:Sedentary Behavior; D014409:Tumor Necrosis Factor-alpha / Q000097:blood*; D055815:Young Adult
chemical_list: D052242:Adiponectin; D015850:Interleukin-6; D014409:Tumor Necrosis Factor-alpha