title: Palladium-catalyzed synthesis of 2-amino ketones from propargylic carbonates and secondary amines.
abstract: A novel palladium-catalyzed approach to 2-amino ketones from arylpropargylic carbonates bearing neutral, electron-rich, and electron-poor aromatic rings and cyclic secondary amines containing useful functional groups such as cyano, chloro, and bromo substituents has been developed.
authors.affiliation: Dipartimento di Chimica e Tecnologie del Farmaco, Sapienza, Università di Roma, P.le A. Moro 5, 00185 Rome, Italy. sandro.cacchi@uniroma1.it
authors.forename: Sandro
authors.initials: S
authors.lastname: Cacchi
authors.forename: Giancarlo
authors.initials: G
authors.lastname: Fabrizi
authors.forename: Eleonora
authors.initials: E
authors.lastname: Filisti
authors.forename: Antonella
authors.initials: A
authors.lastname: Goggiamani
authors.forename: Antonia
authors.initials: A
authors.lastname: Iazzetti
authors.forename: Loredana
authors.initials: L
authors.lastname: Maurone
mesh_terms: D000588:Amines / Q000737:chemistry*; D002254:Carbonates / Q000737:chemistry*; D002384:Catalysis; D007659:Ketones / Q000138:chemical synthesis*; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*
chemical_list: D000588:Amines; D002254:Carbonates; D007659:Ketones; D010165:Palladium