title: High sensitivity C-reactive protein in airline pilots with metabolic syndrome.
abstract: BACKGROUND
  Airline pilots belong to a relatively high-income, healthy population, with sedentary behavior during their flight activity, who often eat unsuitable meals. We assessed the prevalence of metabolic syndrome (MS) and the levels of high sensitivity C-reactive protein (hs-CRP) in a population of airline pilot in order to study a possible relationship between the hs-CRP and MS.
  
  
  METHODS
  MS was established according to the National Cholesterol Education Program, Adult Treatment Panel III. hs-CRP was classified into three categories: Low < 1 mg x L(-1); intermediate: 1-3 mg x L(-1); and high: > 3 mg x L(-1).
  
  
  RESULTS
  The prevalence of MS was 14.8%. The hs-CRP level in the population studied was 1.68 +/- 1.79 mg x L(-1). hs-CRP significantly increased with age. The pilots with MS presented significantly higher hs-CRP levels (median = 1.9 with an interquartile range (IQR) = 2.5 mg x L(-1)) than the pilots without MS (median = 0.9 and IQR = 1.275 mg x L(-1)). MS significantly increased in the groups with high hs-CRP in comparison with pilots with intermediate hs-CRP levels and with those with low hs-CRP levels. A similar association was found between the levels of hs-CRP and the prevalence of MS in the three age groups. The levels of hs-CRP increased in pilots as they presented greater numbers of MS diagnostic criteria.
  
  
  CONCLUSIONS
  hs-CRP rises significantly in pilots of increasing age, in pilots with MS as compared to those without the syndrome, and in pilots as they present greater numbers of MS diagnostic criteria. The prevalence of MS increased among the groups with higher levels of hs-CRP.
authors.affiliation: Institute of Aviation Medicine, Madrid, Spain. caloro1@oc.mde.es
authors.forename: César
authors.initials: C
authors.lastname: Alonso-Rodríguez
authors.forename: Juan
authors.initials: J
authors.lastname: Medina-Font
mesh_terms: D000328:Adult; D000337:Aerospace Medicine; D000368:Aged; D000375:Aging / Q000097:blood; D002097:C-Reactive Protein / Q000032:analysis*; D003430:Cross-Sectional Studies; D006801:Humans; D008297:Male; D024821:Metabolic Syndrome / Q000097:blood* / Q000175:diagnosis; D008875:Middle Aged; D015995:Prevalence; D055815:Young Adult
chemical_list: D002097:C-Reactive Protein