title: Advances in studies on the rupestonic acid derivatives as anti-influenza agents.
abstract: Rupestonic acid (isolated from the Chinese traditional medicine Artemisia rupestris L.) is a sesquiterpene with multifunctional groups and possess higher activity against influenza virus B. In order to improve the biological activity of rupestonic acid, many derivatives have been synthesized and their anti-influenza activity was screened. This review describes the rupestonic acid derivatives and their anti-influenza activity studied by our researching group.
authors.affiliation: State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou 350002, P. R. China. jpyong@fjirsm.ac.cn
authors.forename: Jianping
authors.initials: J
authors.lastname: Yong
authors.forename: Canzhong
authors.initials: C
authors.lastname: Lu
authors.forename: Haji Akber
authors.initials: HA
authors.lastname: Aisa
mesh_terms: D000818:Animals; D000998:Antiviral Agents / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D019306:Artemisia / Q000737:chemistry*; D052176:Azulenes / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D004365:Drugs, Chinese Herbal / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D006801:Humans; D009981:Influenza B virus / Q000187:drug effects; D009975:Orthomyxoviridae / Q000187:drug effects*; D009976:Orthomyxoviridae Infections / Q000188:drug therapy* / Q000821:virology; D012717:Sesquiterpenes / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D013329:Structure-Activity Relationship
chemical_list: D000998:Antiviral Agents; D052176:Azulenes; D004365:Drugs, Chinese Herbal; D012717:Sesquiterpenes; C057488:rupestonic acid