title: Parosteal osteosarcoma mimicking osteochondroma: A radio-histologic approach on two cases.
abstract: BACKGROUND
  Parosteal osteosarcoma is a well-differentiated variant of osteosarcoma that affects the surface of the bone. The imaging pattern is very typical. We report two cases mimicking an osteochondroma, radiologically and histologically and propose an explanation.
  
  
  METHODS
  The review of 86 parosteal osteosarcomas of bone revealed this atypical pattern only once. A consultation case was received in the same time, and added to ours. Patients were 28 years old and 56 years old females. Imaging studies included two radiographs, two CTscans, one MRI examination and one bone scan and the results were compared to histology.
  
  
  RESULTS
  On imaging, both lesions presented as ossified lobulated masses attached with a broad base to the underlying cortex. No radiolucent cleft separated the masses and the host bone and cortex continuity between the mass and the femur was seen, with medullary communication. The marrow of the mass had a different density and intensity compared to normal marrow. So, there were features of an osteochondroma (cortex and medullary continuity) and of a parosteal osteosarcoma (ossified marrow). Pathological assessment on the final specimen confirmed the presence of low-grade parosteal osteosarcomas, after an erroneous diagnosis of osteochondroma on the initial biopsy.
  
  
  CONCLUSIONS
  Parosteal osteosarcoma can be rarely confused with osteochondroma. A radiologic-pathologic correlation is essential. Cortex continuity is the most misleading imaging feature that may occur in parosteal osteosarcomas. A knowledge of this misleading pattern will help diagnose the lesion from the beginning.
authors.forename: Zafiria G
authors.initials: ZG
authors.lastname: Papathanassiou
authors.forename: Marco
authors.initials: M
authors.lastname: Alberghini
authors.forename: Philippe
authors.initials: P
authors.lastname: Thiesse
authors.forename: Marco
authors.initials: M
authors.lastname: Gambarotti
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Bianchi
authors.forename: Cristina
authors.initials: C
authors.lastname: Tranfaglia
authors.forename: Daniel
authors.initials: D
authors.lastname: Vanel