title: Neuronal antibodies and paraneoplastic sensory neuropathy in thymoma.
abstract: Thymoma, a common anterior mediastinal tumour, may present with paraneoplastic neurological symptoms. The presence of neuronal anti-Hu paraneoplastic antibodies in thymoma patients is very rare. Here, we describe a patient who presented with symptoms of a sensory peripheral neuropathy in the presence of onconeural antibodies cross-reactive with Hu antigen, in whom an underlying thymoma was diagnosed. Subsequent minimally invasive thymomectomy improved her neurological symptoms significantly.
authors.affiliation: Thoracic Surgery Department,  Nottingham City Hospital, Nottingham,  UK.
authors.forename: Anupama
authors.initials: A
authors.lastname: Barua
authors.forename: Paul
authors.initials: P
authors.lastname: Gozzard
authors.forename: Antonio E
authors.initials: AE
authors.lastname: Martin-Ucar
authors.forename: Paul
authors.initials: P
authors.lastname: Maddison
mesh_terms: D000369:Aged, 80 and over; D000912:Antibodies, Neoplasm / Q000276:immunology*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D009419:Nerve Tissue Proteins / Q000276:immunology*; D020364:Paraneoplastic Polyneuropathy / Q000175:diagnosis / Q000209:etiology / Q000276:immunology*; D013945:Thymoma / Q000150:complications* / Q000175:diagnosis / Q000276:immunology; D013953:Thymus Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000276:immunology; D014057:Tomography, X-Ray Computed
chemical_list: D000912:Antibodies, Neoplasm; D009419:Nerve Tissue Proteins