title: [Mixed-aetiology extensive ulcers of the crus: postthrombotic disease and gangrenous pyoderma].
abstract: Gangrenous pyoderma (GP) is a rare infectious disease typically manifesting itself by utterly painful crural ulcers. Currently, the disease is considered to be most likely of an autoimmune origin. The author presents herein a case report describing key diagnostic and treatment decisions regarding a 30-year-old woman suffering from extensive crural ulcers. Of special interest was the finding that this patient's ultrasonographic duplex scanning showed the signs corresponding to postthrombotic disease. However, conventional treatment of venous trophic ulcers turned out inefficient. The woman was diagnosed as having GP. Topical therapy with corticosteroid drugs (combined with autodermoplasty and compression therapy) made it possible to achieve complete epithelisation of ulcers. Thus, should conventional treatment of venous trophic ulcers result in the patient's failure to respond properly, it is necessary to take into consideration the probability of gangrenous pyoderma.
authors.forename: D Iu
authors.initials: DIu
authors.lastname: Andreev
mesh_terms: D000287:Administration, Topical; D000305:Adrenal Cortex Hormones / Q000008:administration & dosage; D000328:Adult; D000464:Alginates / Q000627:therapeutic use; D003102:Colloids / Q000627:therapeutic use; D058128:Compression Bandages; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D035002:Lower Extremity / Q000473:pathology / Q000503:physiopathology; D009779:Occlusive Dressings; D054070:Postthrombotic Syndrome / Q000175:diagnosis*; D017511:Pyoderma Gangrenosum / Q000175:diagnosis / Q000473:pathology / Q000503:physiopathology / Q000628:therapy; D016038:Skin Transplantation / Q000009:adverse effects / Q000379:methods*; D016896:Treatment Outcome; D014647:Varicose Ulcer / Q000175:diagnosis*
chemical_list: D000305:Adrenal Cortex Hormones; D000464:Alginates; D003102:Colloids