title: Complete genome sequence of Streptococcus pneumoniae strain ST556, a multidrug-resistant isolate from an otitis media patient.
abstract: Streptococcus pneumoniae is a major pathogen causing bacterial infection in the middle ear of humans. We previously used S. pneumoniae strain ST556, a low-passage 19F isolate from an otitis media patient, to perform a whole-genome screen for ear infection-associated genes in a chinchilla model. This report presents the complete genome sequence of ST556. The genome sequence will provide information complementary to the experimental data from our genetic study of this strain.
authors.affiliation: Center for Infectious Disease Research, School of Medicine, Tsinghua University, Beijing, China.
authors.forename: Guiling
authors.initials: G
authors.lastname: Li
authors.forename: Fen Z
authors.initials: FZ
authors.lastname: Hu
authors.forename: Xianwei
authors.initials: X
authors.lastname: Yang
authors.forename: Yujun
authors.initials: Y
authors.lastname: Cui
authors.forename: Jun
authors.initials: J
authors.lastname: Yang
authors.forename: Fen
authors.initials: F
authors.lastname: Qu
authors.forename: George F
authors.initials: GF
authors.lastname: Gao
authors.forename: Jing-Ren
authors.initials: JR
authors.lastname: Zhang
mesh_terms: D004269:DNA, Bacterial / Q000737:chemistry* / Q000235:genetics*; D024901:Drug Resistance, Multiple, Bacterial; D016680:Genome, Bacterial; D006801:Humans; D008969:Molecular Sequence Data; D010033:Otitis Media / Q000382:microbiology; D011008:Pneumococcal Infections / Q000382:microbiology; D017422:Sequence Analysis, DNA; D013296:Streptococcus pneumoniae / Q000187:drug effects / Q000235:genetics* / Q000302:isolation & purification
chemical_list: D004269:DNA, Bacterial