title: KO(t)Bu mediated synthesis of phenanthridinones and dibenzoazepinones.
abstract: Synthesis of substituted phenanthridinones and dibenzoazepinones has been realized from 2-halo-benzamides in the presence of potassium tert-butoxide and a catalytic amount of 1,10-phenanthroline or AIBN. This new carbon-carbon bond forming reaction gives direct access to various biaryl lactams containing six- and seven-membered rings chemoselectively. Carbon-carbon coupling seems to proceed by the generation of a radical in the amide ring which leads to C-H arylation of aniline.
authors.affiliation: Department of Chemistry, Indian Institute of Science Education and Research Bhopal, Bhopal, MP 462 023, India.
authors.forename: Bhagat Singh
authors.initials: BS
authors.lastname: Bhakuni
authors.forename: Amit
authors.initials: A
authors.lastname: Kumar
authors.forename: Shah Jaimin
authors.initials: SJ
authors.lastname: Balkrishna
authors.forename: Javeed Ahmed
authors.initials: JA
authors.lastname: Sheikh
authors.forename: Sanjit
authors.initials: S
authors.lastname: Konar
authors.forename: Sangit
authors.initials: S
authors.lastname: Kumar