title: Giardia lamblia and respiratory allergies: a study of children from an urban area with a high incidence of protozoan infections.
abstract: OBJECTIVE
  There is a high incidence of intestinal parasite infection in urban areas in the Northeast of Brazil. Giardia lamblia infections have been associated with increased prevalence of cutaneous allergies and gastrointestinal disorders. However, little is known about the relationship between giardiasis and allergic diseases of the airways. The present study aimed to investigate the possible association between respiratory allergic diseases and infections by Giardia lamblia in children from urban areas.
  
  
  METHODS
  This study recruited 110 patients of both sexes aged 5-15 years. Patients were administered a questionnaire evaluating clinical symptoms and were given skin tests, parasite tests and serum tests.
  
  
  RESULTS
  A high incidence of Giardia lamblia was observed (45%, 50/110). Infections by this protozoan were not associated with increased risk of respiratory allergy (p = 0.075), high total IgE levels (p = 0.701), positive specific IgE tests (p = 0.250), or positive skin tests for a range of environmental allergens (p = 0.239).
  
  
  CONCLUSIONS
  This study demonstrated that symptoms of asthma, skin allergy and serum markers were not associated with Giardia lamblia infections in this sample of children from urban areas.
authors.affiliation: Universidade Federal de Pernambuco (UFPE), Recife, PE, Brazil.
authors.forename: Valdênia M O
authors.initials: VM
authors.lastname: Souza
authors.forename: Iana R F
authors.initials: IR
authors.lastname: Sales
authors.forename: Décio M
authors.initials: DM
authors.lastname: Peixoto
authors.forename: Vláudia M Assis
authors.initials: VM
authors.lastname: Costa
authors.forename: José A
authors.initials: JA
authors.lastname: Rizzo
authors.forename: Almerinda R
authors.initials: AR
authors.lastname: Silva
authors.forename: Roberta Faria
authors.initials: RF
authors.lastname: Camilo
authors.forename: Felipe Faria
authors.initials: FF
authors.lastname: Pierotti
authors.forename: Dirceu
authors.initials: D
authors.lastname: Solé
authors.forename: Emanuel S C
authors.initials: ES
authors.lastname: Sarinho
mesh_terms: D000293:Adolescent; D001938:Brazil / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D005260:Female; D016829:Giardia lamblia / Q000302:isolation & purification*; D005873:Giardiasis / Q000150:complications / Q000453:epidemiology*; D006801:Humans; D007073:Immunoglobulin E / Q000097:blood / Q000276:immunology*; D008297:Male; D015995:Prevalence; D012130:Respiratory Hypersensitivity / Q000453:epidemiology / Q000276:immunology* / Q000469:parasitology; D012882:Skin Tests; D011795:Surveys and Questionnaires; D014505:Urban Population / Q000706:statistics & numerical data
chemical_list: D007073:Immunoglobulin E