title: [Biosynthesis of geosmin and 2-methylisoborneol in the prokaryotes--a review].
abstract: The occurrence of off-flavor problems caused by prokaryotes cyanobacteria and actinomycetes is a worldwide water and food quality issue. Based on literatures on two earthy-muddy-smelling metabolites, (i. e., geosmin and 2-methylisoborneol (2-MIB)), we reviewed their chemical characteristics, biosynthetic pathways, genes and enzymes that are involved in biosynthesis. Then we discussed current research questions related to off-flavor and future directions. Finally, we addressed the significance of probable key regulatory mechanism for the production and release of geosmin and 2-MIB, which could provide more scientific strategies to better control off-flavors outbreaks in drinking and aquaculture water.
authors.affiliation: College of Animal Science and Technology, Hunan Agriculture University, Changsha 410128, China. tingzh0517@163.com
authors.forename: Ting
authors.initials: T
authors.lastname: Zhang
authors.forename: Deliang
authors.initials: D
authors.lastname: Li
authors.forename: Jie
authors.initials: J
authors.lastname: Li
mesh_terms: D039903:Actinobacteria / Q000378:metabolism*; D001892:Camphanes / Q000737:chemistry / Q000378:metabolism*; D000458:Cyanobacteria / Q000378:metabolism*; D009284:Naphthols / Q000737:chemistry / Q000378:metabolism*
chemical_list: D001892:Camphanes; D009284:Naphthols; C005536:2-methylisoborneol; C001278:geosmin