title: Fluorogenic and chromogenic probe for rapid detection of a nerve agent simulant DCP.
abstract: A fluorogenic and visual probe was devised to detect diethyl chlorophosphate (DCP), a nerve agent simulant. The probe, N-(rhodamine B)-lactam-2-aminoethanol (RB-AE), undergoes oxazoline formation following phosphorylation in the presence of DCP, which gives rapid and clear fluorescence and color change in the assay solutions.
authors.affiliation: Institute of Chemical Defence, Beijing 102205, PR China. wuwh2012@163.com
authors.forename: Wei-hui
authors.initials: WH
authors.lastname: Wu
authors.forename: Jun-jun
authors.initials: JJ
authors.lastname: Dong
authors.forename: Xin
authors.initials: X
authors.lastname: Wang
authors.forename: Jian
authors.initials: J
authors.lastname: Li
authors.forename: Shao-hui
authors.initials: SH
authors.lastname: Sui
authors.forename: Gao-yun
authors.initials: GY
authors.lastname: Chen
authors.forename: Ji-wei
authors.initials: JW
authors.lastname: Liu
authors.forename: Ming
authors.initials: M
authors.lastname: Zhang
mesh_terms: D002491:Central Nervous System Agents / Q000032:analysis* / Q000737:chemistry*; D003116:Color; D005456:Fluorescent Dyes / Q000737:chemistry*; D009943:Organophosphorus Compounds / Q000032:analysis* / Q000737:chemistry*; D012235:Rhodamines / Q000737:chemistry*; D013997:Time Factors
chemical_list: D002491:Central Nervous System Agents; D005456:Fluorescent Dyes; D009943:Organophosphorus Compounds; D012235:Rhodamines; C548970:diethylchlorophosphate; C029773:rhodamine B