title: Modular design of an ultrahigh-intensity nanoparticle probe for cancer cell imaging and rapid visual detection of nucleic acids.
abstract: Based on a modular design, a novel ultrahigh-intensity nanoparticle probe was synthesized by orderly assembling supramolecular DNA/CdTe quantum dot nanowires and recognition DNA sequences on polystyrene microbeads. The probe was successfully applied to cancer cell imaging and visual detection of nucleic acids.
authors.affiliation: Key Laboratory of Biochemical Analysis, Ministry of Education, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, China.
authors.forename: Hua
authors.initials: H
authors.lastname: Zhong
authors.forename: Rumin
authors.initials: R
authors.lastname: Zhang
authors.forename: Hui
authors.initials: H
authors.lastname: Zhang
authors.forename: Shusheng
authors.initials: S
authors.lastname: Zhang
mesh_terms: D019187:Cadmium Compounds / Q000737:chemistry; D045744:Cell Line, Tumor; D004247:DNA / Q000737:chemistry; D003952:Diagnostic Imaging; D006801:Humans; D015335:Molecular Probes / Q000138:chemical synthesis / Q000737:chemistry*; D053758:Nanoparticles / Q000737:chemistry*; D053770:Nanowires / Q000737:chemistry; D009369:Neoplasms / Q000473:pathology*; D009696:Nucleic Acids / Q000032:analysis*; D010316:Particle Size; D011137:Polystyrenes / Q000737:chemistry; D045663:Quantum Dots; D013499:Surface Properties; D013691:Tellurium / Q000737:chemistry
chemical_list: D019187:Cadmium Compounds; D015335:Molecular Probes; D009696:Nucleic Acids; D011137:Polystyrenes; D004247:DNA; D013691:Tellurium; C028337:cadmium telluride