title: [Comparative morphology of tissues when using polypropylene and polytetrafluoretilen prostheses].
abstract: The synthetic mesh is widely used for treatment of hernias. We conducted a comparative study of the morphological pattern of inflammation, the cellular composition of tissues and dynamics of scar formation in mice when using implants "Esfil" and "Unifleks" under influence of single and double injection of cultured fibroblast and without such injection to the region of stents location. A more pronounced inflammatory reaction during the study period of investigation was observed in the case of "Esfil". In the late period of the study, a higher percentage of fibroblasts was observed in the case of the prosthesis "Unifleks" compared to the prosthesis "Esfil". Injection of cultured fibroblasts modifies the curve of the dynamics of the inflammatory process by making it smoother in the case of both prostheses. So, more preferred is the use of prostheses "Unifleks".
authors.forename: S V
authors.initials: SV
authors.lastname: Ivanov
authors.forename: I S
authors.initials: IS
authors.lastname: Ivanov
authors.forename: G N
authors.initials: GN
authors.lastname: Goriainova
authors.forename: A V
authors.initials: AV
authors.lastname: Tsukanov
authors.forename: T P
authors.initials: TP
authors.lastname: Katunina
mesh_terms: D000818:Animals; D001672:Biocompatible Materials / Q000494:pharmacology; D002465:Cell Movement / Q000187:drug effects* / Q000276:immunology; D017690:Cell Transplantation; D002478:Cells, Cultured; D002921:Cicatrix / Q000276:immunology / Q000473:pathology; D003238:Connective Tissue / Q000187:drug effects* / Q000276:immunology / Q000473:pathology; D005347:Fibroblasts / Q000166:cytology* / Q000276:immunology; D059685:Herniorrhaphy; D006801:Humans; D007249:Inflammation / Q000276:immunology / Q000473:pathology; D008214:Lymphocytes / Q000166:cytology / Q000276:immunology; D008264:Macrophages / Q000166:cytology / Q000276:immunology; D008297:Male; D051379:Mice; D011126:Polypropylenes / Q000494:pharmacology*; D011138:Polytetrafluoroethylene / Q000494:pharmacology*; D019736:Prostheses and Implants / Q000009:adverse effects; D019919:Prosthesis Implantation; D013526:Surgical Mesh / Q000009:adverse effects
chemical_list: D001672:Biocompatible Materials; D011126:Polypropylenes; D011138:Polytetrafluoroethylene