title: Antibiotic resistance of Streptococcus agalactiae from cows with mastitis.
abstract: The aim of this study was to characterise the phenotypic and genotypic antibiotic resistance patterns of Streptococcus agalactiae isolated from cows with mastitis in China. Antibiotic resistance was based on minimum inhibitory concentrations and detection of resistance genes by PCR. S. agalactiae isolates most frequently exhibited phenotypic resistance to tetracycline, while the resistance genes most frequently detected were ermB, tetL and tetM. Resistance genes were detected in some susceptible isolates, whereas no resistance genes could be detected in some resistant isolates, indicating that the resistance genotype does not accurately predict phenotypic resistance.
authors.affiliation: College of Veterinary Medicine, China Agricultural University, Yuan Ming Yuan West Road No. 2, Haidian District, Beijing 100193, China.
authors.forename: Jian
authors.initials: J
authors.lastname: Gao
authors.forename: Fu-Qing
authors.initials: FQ
authors.lastname: Yu
authors.forename: Li-Ping
authors.initials: LP
authors.lastname: Luo
authors.forename: Jian-Zhong
authors.initials: JZ
authors.lastname: He
authors.forename: Rong-Guang
authors.initials: RG
authors.lastname: Hou
authors.forename: Han-Qi
authors.initials: HQ
authors.lastname: Zhang
authors.forename: Shu-Mei
authors.initials: SM
authors.lastname: Li
authors.forename: Jing-Liang
authors.initials: JL
authors.lastname: Su
authors.forename: Bo
authors.initials: B
authors.lastname: Han
mesh_terms: D000583:Amikacin / Q000494:pharmacology; D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001426:Bacterial Proteins / Q000235:genetics* / Q000378:metabolism; D002417:Cattle; D002681:China; D024881:Drug Resistance, Bacterial; D004917:Erythromycin / Q000494:pharmacology; D005260:Female; D005838:Genotype; D005839:Gentamicins / Q000494:pharmacology; D008414:Mastitis, Bovine / Q000382:microbiology*; D008826:Microbial Sensitivity Tests / Q000662:veterinary; D010400:Penicillin G / Q000494:pharmacology; D010641:Phenotype; D013292:Streptococcus agalactiae / Q000187:drug effects* / Q000235:genetics* / Q000302:isolation & purification; D013752:Tetracycline / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; D005839:Gentamicins; D004917:Erythromycin; D000583:Amikacin; D013752:Tetracycline; D010400:Penicillin G