title: S1P1 and S1P3 are potential markers of cardiac microangiopathy in diabetes.
abstract: The prevalence of diabetes is rising rapidly throughout the world, accompanying with the increased occurrence of cardiovascular diseases in clinic. For now, the diagnosis of diabetic cardiovascular diseases has mainly based on the measurement of glucose levels in blood and cardiac function via electrocardiogram and ultrasound cardiogram. However, growing evidence strongly suggests that the assessment of Sphingosine-1-phosphate receptor 1/3 (S1P1/3) own advantages over present measurements in predicting the risk of developing diabetic cardiovascular diseases. This hypothesis may provide concept foundation for improving early diagnosis of cardiac microangiopathy in diabetes.
authors.affiliation: Department of Cardiology, Xijing Hospital, The Fourth Military Medical University, Xi'an City, Shaanxi Province, China.
authors.forename: Zhiyong
authors.initials: Z
authors.lastname: Yin
authors.forename: Linni
authors.initials: L
authors.lastname: Fan
authors.forename: Hongbing
authors.initials: H
authors.lastname: Jia
authors.forename: Congye
authors.initials: C
authors.lastname: Li
authors.forename: Rongqing
authors.initials: R
authors.lastname: Zhang
authors.forename: Haichang
authors.initials: H
authors.lastname: Wang
mesh_terms: D015415:Biomarkers / Q000097:blood; D003925:Diabetic Angiopathies / Q000097:blood* / Q000175:diagnosis*; D058065:Diabetic Cardiomyopathies / Q000097:blood* / Q000175:diagnosis*; D006801:Humans
chemical_list: D015415:Biomarkers