title: [Cross-section study on co-infection of HIV and Cryptosporidium].
abstract: OBJECTIVE
  To investigate the co-infection status of HIV and Cryptosporidium, and explore the influencing factors associated with the co-infection.
  
  
  METHODS
  A total of 309 people with HIV positive in Fuyang City of Anhui Province were recruited and their fecal and blood samples were collected for examinations of Cryptosporidium spp. infection and the levels of hemoglobin, cytokines and CD4+/CD8+ T-lymphocytes. Meanwhile, the questionnaire survey was conducted.
  
  
  RESULTS
  Among 302 people involved in fecal examinations, the infection rate of Cryptosporidium spp. was 8.28%, and the difference between infection rates of the male (13.49%) and the female (2.92%) was statistically significant (P < 0.05). The multivariate logistic regression model showed that 4 factors were significantly associated with the coinfection of HIV and Cryptosporidium spp, including male (OR = 6.700, 95% CI: 2.030, 22.114), younger than 42 years old (OR = 4.148, 95% CI: 1.348, 12.761), level of IL-2 below 77 pg/ml (OR = 0.226, 95%CI: 0.076, 0.674) and personal hygiene habits (OR = 0.324, 95% CI: 0.105, 0.994).
  
  
  CONCLUSIONS
  The co-infection rate of Cryptosporidium spp. and HIV is high, the key targets of control are the people who are male, younger than 42 years old, with high level of IL2 and poor personal hygiene habits.
authors.affiliation: National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, WHO Collaborating Center for Malaria, Schistosomiasis and Filariasis, Shanghai 200025, China.
authors.forename: Li-Guang
authors.initials: LG
authors.lastname: Tian
authors.forename: Tian-Ping
authors.initials: TP
authors.lastname: Wang
authors.forename: Guo-Jin
authors.initials: GJ
authors.lastname: Cheng
authors.forename: Feng-Feng
authors.initials: FF
authors.lastname: Wang
authors.forename: Xiao-Mei
authors.initials: XM
authors.lastname: Tong
authors.forename: Jian
authors.initials: J
authors.lastname: Guo
authors.forename: Yu-Chun
authors.initials: YC
authors.lastname: Cai
authors.forename: Jia-Xu
authors.initials: JX
authors.lastname: Chen
authors.forename: Xiao-Nong
authors.initials: XN
authors.lastname: Zhou
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000150:complications* / Q000469:parasitology / Q000821:virology; D000328:Adult; D003430:Cross-Sectional Studies; D003457:Cryptosporidiosis / Q000150:complications* / Q000469:parasitology / Q000821:virology; D003458:Cryptosporidium / Q000302:isolation & purification*; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male