title: Paediatric acute basilar thrombosis successfully treated with intravenous alteplase.
abstract: Acute ischaemic stroke has significant attendant morbidity and is one of the top ten causes of childhood death. It requires prompt investigation and management, however little is known about the safety and efficacy of acute thrombolytic therapies in childhood arterial ischaemic stroke. The authors report a case of a 13-year-old girl with an acute basilar thrombosis, successfully treated with intravenous recombinant tissue plasminogen activator and discuss the management of paediatric arterial ischaemic stroke.
authors.affiliation: Paediatric Neurology Unit, Paediatrics Department, Hospital Central do Funchal, Funchal, Portugal. pauloregodesousa@portugalmail.pt
authors.forename: Paulo
authors.initials: P
authors.lastname: Rego Sousa
authors.forename: Rui
authors.initials: R
authors.lastname: Vasconcellos
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D001488:Basilar Artery; D003937:Diagnosis, Differential; D005260:Female; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D006801:Humans; D007262:Infusions, Intravenous; D008279:Magnetic Resonance Imaging; D020521:Stroke / Q000175:diagnosis* / Q000188:drug therapy*; D010959:Tissue Plasminogen Activator / Q000627:therapeutic use*; D014057:Tomography, X-Ray Computed
chemical_list: D005343:Fibrinolytic Agents; D010959:Tissue Plasminogen Activator