title: Interactions between occlusion and human brain function activities.
abstract: There are few review articles in the area of human research that focus on the interactions between occlusion and brain function. This systematic review discusses the effect of occlusion on the health of the entire body with a focus on brain function. Available relevant articles in English from 1999 to 2011 were assessed in an online database and as hard copies in libraries. The selected 19 articles were classified into the following five categories: chewing and tongue movements, clenching and grinding, occlusal splints and occlusal interference, prosthetic rehabilitation, and pain and stimulation. The relationships between the brain activity observed in the motor and sensory cortices and movements of the oral and maxillofacial area, such as those produced by gum chewing, tapping and clenching, were investigated. It was found that the sensorimotor cortex was also affected by the placement of the occlusal interference devices, splints and implant prostheses. Brain activity may change depending on the strength of the movements in the oral and maxillofacial area. Therefore, mastication and other movements stimulate the activity in the cerebral cortex and may be helpful in preventing degradation of a brain function. However, these findings must be verified by evidence gathered from more subjects.
authors.affiliation: Department of Removable Prosthodontics, Tsurumi University School of Dental Medicine, Yokohama, Japan. okubo-c@tsurumi-u.ac.jp
authors.forename: C
authors.initials: C
authors.lastname: Ohkubo
authors.forename: M
authors.initials: M
authors.lastname: Morokuma
authors.forename: Y
authors.initials: Y
authors.lastname: Yoneyama
authors.forename: R
authors.initials: R
authors.lastname: Matsuda
authors.forename: J S
authors.initials: JS
authors.lastname: Lee
mesh_terms: D002012:Bruxism / Q000503:physiopathology; D002540:Cerebral Cortex / Q000502:physiology*; D003766:Dental Occlusion; D003769:Dental Occlusion, Traumatic / Q000503:physiopathology*; D017266:Dental Prosthesis; D006304:Health Status; D006801:Humans; D008409:Mastication / Q000502:physiology*; D017090:Occlusal Splints; D014059:Tongue / Q000502:physiology; D014098:Toothache / Q000503:physiopathology