title: Involuntary movements after correction of vitamin B12 deficiency: a video-case report.
abstract: Involuntary movements can appear before and after initiation of vitamin B12 treatment. The pathogenesis of involuntary movements in vitamin B12 deficiency and their relationship with cobalamin injection remain unclear due to a lack of video-EEG documentation making the electroclinical correlation difficult to ascertain. Here, we report video-EEG and neuroimaging findings of an 11-month-old girl with vitamin B12 deficiency, who acutely developed involuntary movements a few days after initiation of vitamin B12 treatment with normal vitamin plasmatic levels. Abnormal movements were a combination of tremor and myoclonus involving the face, mouth, and left arm, which disappeared after discontinuation of therapy. [Published with video sequences].
authors.affiliation: Institute for Maternal and Child Health, IRCCS "Burlo Garofolo" Trieste, Italy.
authors.forename: Caterina
authors.initials: C
authors.lastname: Zanus
authors.forename: Elena
authors.initials: E
authors.lastname: Alberini
authors.forename: Paola
authors.initials: P
authors.lastname: Costa
authors.forename: Franco
authors.initials: F
authors.lastname: Colonna
authors.forename: Floriana
authors.initials: F
authors.lastname: Zennaro
authors.forename: Marco
authors.initials: M
authors.lastname: Carrozzi
mesh_terms: D001284:Atrophy; D001921:Brain / Q000473:pathology; D020820:Dyskinesias / Q000209:etiology*; D004569:Electroencephalography; D005260:Female; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D009186:Myelin Sheath / Q000473:pathology; D009207:Myoclonus / Q000139:chemically induced; D014202:Tremor / Q000139:chemically induced; D014741:Video Recording; D014805:Vitamin B 12 / Q000627:therapeutic use*; D014806:Vitamin B 12 Deficiency / Q000150:complications* / Q000188:drug therapy*; D014815:Vitamins / Q000627:therapeutic use*
chemical_list: D014815:Vitamins; D014805:Vitamin B 12