title: Regulation of the growth of cotton bollworms by metabolites from an entomopathogenic fungus Paecilomyces cateniobliquus.
abstract: Chemical investigation of one entomopathogenic fungus Paecilomyces cateniobliquus YMF1.01799 led to the isolation and identification of six metabolites, which include three new compounds (2-3, and 5) and three known metabolites. Their structures were established by spectroscopic studies such as 1D and 2D NMR and MS analysis. Insect growth experiments suggested that polyketide-derived compound 1 showed significant inhibitory effect on the growth of cotton bollworm Helicoverpa armigera, while terpenoid-derived metabolite 5 promoted the growth of the larvae. The findings revealed that the entomopathogenic fungus P. cateniobliquus could produce different types of metabolites to regulate growth of the insect.
authors.affiliation: Key Laboratory for Microbial Resources of the Ministry of Education, Yunnan University, Kunming 650091, People's Republic of China.
authors.forename: Hong-Yang
authors.initials: HY
authors.lastname: Wu
authors.forename: Yan-Li
authors.initials: YL
authors.lastname: Wang
authors.forename: Jian-Lin
authors.initials: JL
authors.lastname: Tan
authors.forename: Chun-Yan
authors.initials: CY
authors.lastname: Zhu
authors.forename: Dong-Xian
authors.initials: DX
authors.lastname: Li
authors.forename: Rong
authors.initials: R
authors.lastname: Huang
authors.forename: Ke-Qin
authors.initials: KQ
authors.lastname: Zhang
authors.forename: Xue-Mei
authors.initials: XM
authors.lastname: Niu
mesh_terms: D000818:Animals; D001685:Biological Factors / Q000378:metabolism / Q000494:pharmacology*; D007814:Larva / Q000187:drug effects / Q000254:growth & development; D009036:Moths / Q000187:drug effects* / Q000254:growth & development*; D010143:Paecilomyces / Q000737:chemistry / Q000378:metabolism*; D061065:Polyketides / Q000494:pharmacology; D013729:Terpenes / Q000494:pharmacology
chemical_list: D001685:Biological Factors; D061065:Polyketides; D013729:Terpenes