title: Sol-gel-derived hydroxyapatite-carbon nanotube/titania coatings on titanium substrates.
abstract: In this paper, hydroxyapatite-carbon nanotube/titania (HA-CNT/TiO(2)) double layer coatings were successfully developed on titanium (Ti) substrates intended for biomedical applications. A TiO(2) coating was firstly developed by anodization to improve bonding between HA and Ti, and then the layer of HA and CNTs was coated on the surface by the sol-gel process to improve the biocompatibility and mechanical properties of Ti. The surfaces of double layer coatings were uniform and crack-free with a thickness of about 7 μm. The bonding strength of the HA-CNT/TiO(2) coating was higher than that of the pure HA and HA-CNT coatings. Additionally, in vitro cell experiments showed that CNTs promoted the adhesion of preosteoblasts on the HA-CNT/TiO(2) double layer coatings. These unique surfaces combined with the osteoconductive properties of HA exhibited the excellent mechanical properties of CNTs. Therefore, the developed HA-CNT/TiO(2) coatings on Ti substrates might be a promising material for bone replacement.
authors.affiliation: Department of Prosthodontics, School and Hospital of Stomatology, Wenzhou Medical College, Wenzhou 325027, China.
authors.forename: Xiaoli
authors.initials: X
authors.lastname: Ji
authors.affiliation: Department of Prosthodontics, School and Hospital of Stomatology, Wenzhou Medical College, Wenzhou 325027, China.
authors.forename: Weiwei
authors.initials: W
authors.lastname: Lou
authors.affiliation: State Key Laboratory of Oral Diseases, West China Stomatology Hospital, Sichuan University, Chengdu 610041, China.
authors.forename: Qi
authors.initials: Q
authors.lastname: Wang
authors.affiliation: Department of Prosthodontics, School and Hospital of Stomatology, Wenzhou Medical College, Wenzhou 325027, China.
authors.forename: Jianfeng
authors.initials: J
authors.lastname: Ma
authors.affiliation: Department of Prosthodontics, School and Hospital of Stomatology, Wenzhou Medical College, Wenzhou 325027, China.
authors.forename: Haihong
authors.initials: H
authors.lastname: Xu
authors.affiliation: Department of Prosthodontics, School and Hospital of Stomatology, Wenzhou Medical College, Wenzhou 325027, China.
authors.forename: Qing
authors.initials: Q
authors.lastname: Bai
authors.affiliation: Department of Prosthodontics, School and Hospital of Stomatology, Wenzhou Medical College, Wenzhou 325027, China.
authors.forename: Chuantong
authors.initials: C
authors.lastname: Liu
authors.affiliation: Department of Prosthodontics, School and Hospital of Stomatology, Wenzhou Medical College, Wenzhou 325027, China.
authors.forename: Jinsong
authors.initials: J
authors.lastname: Liu
mesh_terms: D018786:Bone Substitutes / Q000737:chemistry*; D002448:Cell Adhesion / Q000502:physiology; D049109:Cell Proliferation; D020099:Coated Materials, Biocompatible / Q000737:chemistry*; D017886:Durapatite / Q000737:chemistry; D008422:Materials Testing; D008855:Microscopy, Electron, Scanning; D037742:Nanotubes, Carbon / Q000737:chemistry*; D010006:Osteoblasts / Q000502:physiology*; D044367:Phase Transition; D017550:Spectroscopy, Fourier Transform Infrared; D014025:Titanium / Q000737:chemistry*
chemical_list: D018786:Bone Substitutes; D020099:Coated Materials, Biocompatible; D037742:Nanotubes, Carbon; C009495:titanium dioxide; D017886:Durapatite; D014025:Titanium