title: False aneurysm of ascending aorta due to pericardial mesothelioma.
abstract: Ascending aortic false aneurysm is a rare but serious complication of pericardial mesothelioma. We report a case of ascending aortic pseudoaneurysm due to spindle cell pericardial mesothelioma. In this case, the first symptoms of the disease appeared 18 months before surgery. The final diagnosis was determined only when severe late complications occurred. Palliative tumour excision, aortoplasty and aortic valve prosthesis were performed with subsequent adjuvant chemotherapy. Over 10 months after surgery, the patient is alive and a significant reduction of the tumour mass has been achieved. This case demonstrates that timely lifetime diagnosis of malignant pericardial tumour remains very difficult and effective adjuvant chemotherapy is needed to improve the results of surgery.
authors.affiliation: Almazov Federal Heart, Blood and Endocrinology Centre, St. Petersburg, Russian Federation. vladimiruspenskiy@gmail.com
authors.forename: Vladimir
authors.initials: V
authors.lastname: Uspenskiy
authors.forename: Alexei
authors.initials: A
authors.lastname: Lavreshin
authors.forename: Alexei
authors.initials: A
authors.lastname: Osadchii
authors.forename: Michael
authors.initials: M
authors.lastname: Gordeev
mesh_terms: D000328:Adult; D017541:Aneurysm, False / Q000209:etiology* / Q000601:surgery; D001014:Aortic Aneurysm / Q000209:etiology* / Q000601:surgery; D001027:Aortography / Q000379:methods; D019917:Blood Vessel Prosthesis Implantation; D017024:Chemotherapy, Adjuvant; D006338:Heart Neoplasms / Q000150:complications* / Q000473:pathology / Q000628:therapy; D019918:Heart Valve Prosthesis Implantation; D006801:Humans; D018810:Magnetic Resonance Angiography; D008297:Male; D008654:Mesothelioma / Q000150:complications* / Q000473:pathology / Q000628:therapy; D010496:Pericardium / Q000473:pathology; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome