title: Regio- and stereoselective syntheses of piperidine derivatives via ruthenium-catalyzed coupling of propargylic amides and allylic alcohols.
abstract: Intermolecular selective coupling of linear allylic alcohols and propargylic amides occurs in the presence of a catalytic amount of the cationic ruthenium complex [Cp*Ru(NCCH(3))(3)]PF(6) followed by condensation to generate six-membered cyclic enamides or hemiaminal ethers with water as the only side product.
authors.affiliation: UMR 6226 CNRS-Université de Rennes 1, Institut des Sciences chimiques de Rennes, Organometallics: Materials and Catalysis, Campus de Beaulieu, 35042 Rennes Cedex, France.
authors.forename: Sathiyamoorthy
authors.initials: S
authors.lastname: Murugesan
authors.forename: Fan
authors.initials: F
authors.lastname: Jiang
authors.forename: Mathieu
authors.initials: M
authors.lastname: Achard
authors.forename: Christian
authors.initials: C
authors.lastname: Bruneau
authors.forename: Sylvie
authors.initials: S
authors.lastname: Dérien
mesh_terms: D000577:Amides / Q000737:chemistry*; D002384:Catalysis; D056831:Coordination Complexes / Q000737:chemistry; D004987:Ethers / Q000737:chemistry; D010880:Piperidines / Q000138:chemical synthesis* / Q000737:chemistry; D020005:Propanols / Q000737:chemistry*; D012428:Ruthenium / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000577:Amides; D056831:Coordination Complexes; D004987:Ethers; D010880:Piperidines; D020005:Propanols; C006463:allyl alcohol; D012428:Ruthenium