title: Parvovirus B19 infection and severe anemia in renal transplant recipients.
abstract: Kidney transplant (KT) recipients can develop symptomatic Parvovirus (PV) B19 infections, frequently associated with persistent anemia. The aim of this study was to evaluate the prevalence and clinical significance of PV B19 infection in anemic and non-anemic KT patients. Overall, out of 64 patients monitored for the presence of PV B19 by real-time PCR, 2 (3.12%) had an active PV B19 infection, in absence of other viral coinfections. The 2 cases occurred in nonanemic kidney transplant patients group (2/50, 4%), while none of the anemic transplant patients (0/14) was found to suffer from this infection. Moreover, patients affected by active PV B19 infection showed viral loads not exceeding 1 × 10(5) genome copies/reaction. In conclusion, in this study, PV B19 infection was not common in renal transplant population and wasn't associated with severe anemia.
authors.affiliation: Clinical Pathology Laboratory, Santa Maria Goretti Hospital, AUSL Latina, 04100 Latina, Italy. carraturo.antonio@gmail.com
authors.forename: Antonio
authors.initials: A
authors.lastname: Carraturo
authors.forename: Valentina
authors.initials: V
authors.lastname: Catalani
authors.forename: Donatella
authors.initials: D
authors.lastname: Ottaviani
authors.forename: Patrizia
authors.initials: P
authors.lastname: Menichelli
authors.forename: Maurizio
authors.initials: M
authors.lastname: Rossini
authors.forename: Delia
authors.initials: D
authors.lastname: Terella
authors.forename: Brunello
authors.initials: B
authors.lastname: Biondi
mesh_terms: D000328:Adult; D000368:Aged; D000740:Anemia / Q000150:complications*; D005260:Female; D006801:Humans; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D010322:Parvoviridae Infections / Q000150:complications*; D016732:Parvovirus B19, Human / Q000302:isolation & purification*; D060888:Real-Time Polymerase Chain Reaction