title: Cytomegalovirus infection and the gastrointestinal tract.
abstract: Cytomegalovirus (CMV) infection is common worldwide, but the majority are asymptomatic. However, during initial infection or reactivation, CMV can cause tissue-invasive end-organ damage including in the gastrointestinal tract, especially in immunocompromised individuals. Gastrointestinal CMV disease can present with myriad of symptoms and be highly variable endoscopically. In this article we review the manifestations of CMV infection within the luminal gastrointestinal tract and discuss the options for diagnosis and management.
authors.affiliation: Department of Gastroenterology, Naval Medical Center, San Diego, CA 92134, USA. David.You@med.navy.mil
authors.forename: David M
authors.initials: DM
authors.lastname: You
authors.forename: Mark D
authors.initials: MD
authors.lastname: Johnson
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000150:complications; D000998:Antiviral Agents / Q000627:therapeutic use; D003586:Cytomegalovirus Infections / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D015774:Ganciclovir / Q000627:therapeutic use; D005759:Gastroenteritis / Q000175:diagnosis* / Q000188:drug therapy / Q000821:virology; D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000150:complications; D009894:Opportunistic Infections / Q000150:complications; D016377:Organ Transplantation
chemical_list: D000998:Antiviral Agents; D015774:Ganciclovir