title: Enhancer dysfunction: how the main regulators of gene expression contribute to cancer.
abstract: A genome-wide epigenetic analysis of enhancer elements in colon cancer has implicated distal gene regulatory DNA sequences in the establishment of an oncogenic transcriptional program.
authors.affiliation: Department of Biological Chemistry and Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, David Geff en School of Medicine, University of California, Los Angeles, CA 90095, USA. skurdistani@mednet.ucla.edu
authors.forename: Siavash K
authors.initials: SK
authors.lastname: Kurdistani
mesh_terms: D003110:Colonic Neoplasms / Q000235:genetics / Q000378:metabolism; D004742:Enhancer Elements, Genetic / Q000235:genetics*; D015870:Gene Expression; D020869:Gene Expression Profiling / Q000379:methods; D015894:Genome, Human; D006801:Humans; D012045:Regulatory Sequences, Nucleic Acid; D014158:Transcription, Genetic