title: [Measurement and preliminary human health risk assessment of representative organochlorines in farmed Mandarin fish].
abstract: Concentrations of representative organochlorines (OCs), including organochlorine pesticides (OCPs) and polychlorinated biphenyls (PCBs) in a batch of farmed mandarin fish from a cultivation pond in Wujiang City, Jiangsu Province, were determined with GC-ECD. Meanwhile, a preliminary human health risk assessment was conducted. Results showed that, the concentrations of dichlorodiphenyltrichloroethanes (DDTs), hexachlorocyclohexanes (HCHs), hexachlorobenzene (HCB) and PCBs in the farmed mandarin fish were in the range of 1.3-4.57 ng/g, 0.13-1.24 ng/g, 0.07-0.44 ng/g and 0-5.22 ng/g, respectively, with an average value of 2.96, 0.40, 1.27 and 0.7 ng/g, respectively. These values were far below the corresponding residue limits set by China's Ministry of Health and the U.S. Food and Drug Administration, and at the low end of the global pollution bar. Referring to the reference values given by USEPA Integrated Risk Information System, calculated non-carcinogenic hazard ratios (HRs) of DDTs, HCB and PCBs were all <1 and carcinogenic HRs of DDTs, HCHs, HCB and PCBs were all >1. The results indicated that DDTs, HCHs and HCB in farmed mandarin fish did not have negative human health influence, but existed potential carcinogenic risk to humans. Compared to rural residents, urban residents were more vulnerable to DDTs, HCHs, HCB and PCBs threats.
authors.affiliation: Key Laboratory of Yangtze River Water Environment, Ministry of Education, College of Environmental Science and Engineering, Tongji University, Shanghai 200092, China. madai1989@126.com
authors.forename: Ying
authors.initials: Y
authors.lastname: Wang
authors.forename: Yan-Ling
authors.initials: YL
authors.lastname: Qiu
authors.forename: Yong
authors.initials: Y
authors.lastname: Fei
authors.forename: Li
authors.initials: L
authors.lastname: Li
authors.forename: Zhi-Liang
authors.initials: ZL
authors.lastname: Zhu
authors.forename: Jian-Fu
authors.initials: JF
authors.lastname: Zhao
authors.forename: En-Qin
authors.initials: EQ
authors.lastname: Yao
authors.forename: Yu-Xin
authors.initials: YX
authors.lastname: Yao
mesh_terms: D000818:Animals; D017756:Aquaculture; D002681:China; D003634:DDT / Q000032:analysis; D005396:Fish Products / Q000032:analysis*; D005399:Fishes / Q000254:growth & development*; D001556:Hexachlorocyclohexane / Q000032:analysis; D006801:Humans; D006843:Hydrocarbons, Chlorinated / Q000032:analysis*; D011078:Polychlorinated Biphenyls / Q000032:analysis*; D018570:Risk Assessment; D014874:Water Pollutants, Chemical / Q000032:analysis*
chemical_list: D006843:Hydrocarbons, Chlorinated; D014874:Water Pollutants, Chemical; D001556:Hexachlorocyclohexane; D003634:DDT; D011078:Polychlorinated Biphenyls