title: Asymmetric crying face in a newborn with isotretinoin embryopathy.
abstract: We report a newborn with asymmetric crying face and other anomalies whose mother had taken isotretinoin during the first month of pregnancy. We hypothesize that asymmetric crying face is a finding of retinoic acid embryopathy and results from the intrauterine effects of retinoic acid on the development of the depressor anguli oris muscle or the mandibular branch of the facial nerve.
authors.affiliation: Division of Neonatology, Faculty of Medicine, Erciyes University, KayseriDivision of Pediatric Cardiology, Department of Pediatrics, Faculty of Medicine, Erciyes University, KayseriDepartment of Medical Genetics, Faculty of Medicine, Erciyes University, Kayseri, Turkey.
authors.forename: Dilek
authors.initials: D
authors.lastname: Sarici
authors.forename: Mustafa Ali
authors.initials: MA
authors.lastname: Akin
authors.forename: Selim
authors.initials: S
authors.lastname: Kurtoglu
authors.forename: Kazim
authors.initials: K
authors.lastname: Uzum
authors.forename: Aslihan
authors.initials: A
authors.lastname: Kiraz
mesh_terms: D000014:Abnormalities, Drug-Induced / Q000473:pathology*; D000152:Acne Vulgaris / Q000188:drug therapy*; D003448:Crying; D003879:Dermatologic Agents / Q000008:administration & dosage / Q000009:adverse effects; D004423:Ear / Q000002:abnormalities*; D005146:Facial Asymmetry / Q000473:pathology*; D005152:Facial Muscles / Q000002:abnormalities*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D015474:Isotretinoin / Q000008:administration & dosage / Q000009:adverse effects*; D011247:Pregnancy
chemical_list: D003879:Dermatologic Agents; D015474:Isotretinoin