title: Vancomycin hypersensitivity diagnosed by lymphocyte blast transformation.
abstract: A 15-year-old male admitted for Pott's puffy tumor developed recurrent episodes of fever, diffuse morbilliform rash, eosinophilia, and tubulointerstitial nephritis while on multiple antibiotics. Lymphocyte blast transformation (LBT), a method of detecting cellular immune response by measuring levels of interferon-γ (IFN-γ), was used to diagnose vancomycin hypersensitivity and guide antibiotic selection.
authors.affiliation: Allergy/Immunology, Le Bonheur Children's Hospital, Memphis, TN 38103, USA.
authors.forename: Nguyen P
authors.initials: NP
authors.lastname: Tran
authors.forename: Jeremy
authors.initials: J
authors.lastname: Katcher
authors.forename: Erin
authors.initials: E
authors.lastname: Rohman
authors.forename: Mary Francis
authors.initials: MF
authors.lastname: Hall
authors.forename: Christie F
authors.initials: CF
authors.lastname: Michael
authors.forename: Isao
authors.initials: I
authors.lastname: Miyairi
authors.forename: D Betty
authors.initials: DB
authors.lastname: Lew