title: [Is there a link between the occurrence of Kidney cancer and hypertension in Tunisian population?].
abstract: BACKGROUND
  Kidney cancer is generally asymptomatic and discovered incidentally at a late stage, which is a negative diagnosis because in most cases the disease is incurable at this stage. Some predisposing factors have been revealed by studies such high blood pressure, which is a frequent among the Tunisian population.
  
  
  OBJECTIVE
  A study among the Tunisian population to determine if there is a link between the occurrence of kidney cancer and the hypertension.
  
  
  METHODS
  Our work was conducted on 91 patients with confirmed renal cell carcinoma and 91 healthy subjects who consulted the Urology Department at the Charles Nicolle Hospital in Tunis. The study of clinical records has identified the clinical, pathological and therapeutic features of the 182 patients.
  
  
  RESULTS
  59% of individuals with hypertension have developed kidney cancer with a significant p-value equal to 0.03. The more the value of blood pressure increases the more the risk is (p = 0.03). Smoking in combination with hypertension is a factor favoring the occurrence of cancer with a value of p equal to 0.05.
  
  
  CONCLUSIONS
  In the Tunisian population hypertension is a risk factor for developing kidney cancer, a factor compounded by the high incidence of this disease. What prompts us to make explorations of kidney lodges of hypertensive patients.
authors.affiliation: Laboratoie de Génétique Immunologie Humaine, Faculté des Sciences de Tunis.
authors.forename: Imen
authors.initials: I
authors.lastname: Ferchichi
authors.forename: Nadia
authors.initials: N
authors.lastname: Kourda
authors.forename: Amine
authors.initials: A
authors.lastname: Derouiche
authors.forename: Sarra
authors.initials: S
authors.lastname: Baltagi
authors.forename: Mohamed
authors.initials: M
authors.lastname: Chebil
authors.forename: Amel
authors.initials: A
authors.lastname: Benammar-Elgaaied
mesh_terms: D000328:Adult; D002292:Carcinoma, Renal Cell / Q000150:complications / Q000453:epidemiology* / Q000209:etiology*; D004198:Disease Susceptibility; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications* / Q000453:epidemiology*; D015994:Incidence; D007680:Kidney Neoplasms / Q000150:complications / Q000453:epidemiology* / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D011153:Population; D012307:Risk Factors; D012907:Smoking / Q000009:adverse effects / Q000453:epidemiology; D014416:Tunisia / Q000453:epidemiology