title: Combined use of super-oxidised solution with negative pressure for the treatment of pressure ulcers: case report.
abstract: A 61-year-old patient was affected by flaccid paraplegia for 20 years because of post-traumatic medullar injury caused by an accidental fall, with stage IV sacral pressure ulcer for 3 years. The patient later developed stage IV sacral pressure ulcer. After 6 months, a new granulation tissue formation appeared in the wound and a reduction of its diameter was observed (length 20 cm, width 15 cm, depth 5 cm). We therefore treated the wound with PRP (platelet rich plasma) intra-lesion and peri-lesional injections. The wounds were covered with three-dimensional polymerised hyaluronic acid medicated biologic dressing. After the surgery, a moderate reduction in diameter and the depth was observed. Super-oxidised solution (SOS-Dermacyn) was applied to control infection locally together with negative pressure to control the exudate and the local bacteremia, to avoid infectious complications without application of systematic antibiotic therapy.
authors.affiliation: Department of Plastic and Reconstructive Surgery, Policlinico Casilino, University of Rome Tor Vergata, Rome, Italy. bdeangelisdoc@gmail.com
authors.forename: Barbara
authors.initials: B
authors.lastname: de Angelis
authors.forename: Lucilla
authors.initials: L
authors.lastname: Lucarini
authors.forename: Annarita
authors.initials: A
authors.lastname: Agovino
authors.forename: Alessia
authors.initials: A
authors.lastname: Migner
authors.forename: Fabrizio
authors.initials: F
authors.lastname: Orlandi
authors.forename: Micol
authors.initials: M
authors.lastname: Floris
authors.forename: Valerio
authors.initials: V
authors.lastname: Cervelli
authors.forename: Cristiano
authors.initials: C
authors.lastname: Curcio
mesh_terms: D005500:Follow-Up Studies; D006801:Humans; D008875:Middle Aged; D054843:Negative-Pressure Wound Therapy / Q000379:methods*; D016877:Oxidants / Q000494:pharmacology; D053657:Platelet-Rich Plasma; D003668:Pressure Ulcer / Q000628:therapy*; D013481:Superoxides / Q000494:pharmacology*; D014945:Wound Healing
chemical_list: D016877:Oxidants; D013481:Superoxides