title: Detection of carbapenem-resistant Escherichia coli and Klebsiella pneumoniae producing NDM-1 in Lebanon.
abstract: Carbapenem resistance has been encountered globally with poor outcome of infected patients. NDM-1 (New Delhi metallo-beta-lactamase) gene containing organisms have emerged and are now spreading in all continents. This is the first report of Iraqi patients referred to Lebanon from whom carbapenem resistant Enterobacteriaceae were recovered. The genes involved in carbapenem resistance were bla-OXA-48 and the novel NDM-1. This report highlights the alarming introduction of such resistance among Enterobacteriaecae to this country.
authors.affiliation: Division of Infectious Diseases, American University of Beirut Medical Center, Beirut, Lebanon.
authors.forename: Rima I
authors.initials: RI
authors.lastname: El-Herte
authors.forename: George F
authors.initials: GF
authors.lastname: Araj
authors.forename: Ghassan M
authors.initials: GM
authors.lastname: Matar
authors.forename: Maysa
authors.initials: M
authors.lastname: Baroud
authors.forename: Zeina A
authors.initials: ZA
authors.lastname: Kanafani
authors.forename: Souha S
authors.initials: SS
authors.lastname: Kanj
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D015780:Carbapenems / Q000494:pharmacology*; D004269:DNA, Bacterial / Q000235:genetics; D004926:Escherichia coli / Q000201:enzymology* / Q000235:genetics / Q000302:isolation & purification; D004927:Escherichia coli Infections / Q000382:microbiology*; D005798:Genes, Bacterial; D006801:Humans; D007710:Klebsiella Infections / Q000382:microbiology*; D007711:Klebsiella pneumoniae / Q000201:enzymology* / Q000235:genetics / Q000302:isolation & purification; D007861:Lebanon; D018440:beta-Lactam Resistance; D001618:beta-Lactamases / Q000235:genetics / Q000378:metabolism*
chemical_list: D000900:Anti-Bacterial Agents; D015780:Carbapenems; D004269:DNA, Bacterial; D001618:beta-Lactamases; C552864:beta-lactamase NDM-1