title: Insecticide and acaricide molecules and/or combinations to prevent pet infestation by ectoparasites.
abstract: External antiparasitic drugs used in cats and dogs have evolved in terms of active ingredients but also regarding formulations. Old chemical groups have been supplanted by phenylpyrazoles, neonicotinoids, oxadiazines, spinosyns or others which are entering the veterinary market. In addition to insecticides-acaricides, insect and mite growth inhibitors (IGRs) have emerged. These IGRs are used in animals or in the environment, either alone or in combination with insecticides-acaricides. The notion of antiparasitic treatment has evolved to the concept of prevention of ectoparasite infestation but also of transmitted diseases through the introduction of formulations providing long-lasting activity. At the same time, ease-of-use has been improved with the development of spot-on formulations. Progress has also been achieved through the development of antiparasitic drugs providing control of both external and internal parasites.
authors.affiliation: Merial, 29 Av. Tony Garnier, 69007 Lyon, France. Frederic.beugnet@merial.com
authors.forename: Frédéric
authors.initials: F
authors.lastname: Beugnet
authors.forename: Michel
authors.initials: M
authors.lastname: Franc
mesh_terms: D056810:Acaricides / Q000009:adverse effects / Q000737:chemistry / Q000494:pharmacology*; D000818:Animals; D001181:Arthropods / Q000187:drug effects; D002371:Cat Diseases / Q000188:drug therapy* / Q000469:parasitology / Q000635:transmission; D002415:Cats; D004283:Dog Diseases / Q000188:drug therapy* / Q000469:parasitology / Q000635:transmission; D004285:Dogs; D004359:Drug Therapy, Combination; D004478:Ectoparasitic Infestations / Q000188:drug therapy / Q000517:prevention & control / Q000635:transmission / Q000662:veterinary*; D007306:Insecticides / Q000009:adverse effects / Q000737:chemistry / Q000494:pharmacology*; D010755:Organophosphates / Q000009:adverse effects / Q000737:chemistry / Q000494:pharmacology; D010273:Parasitic Diseases, Animal / Q000188:drug therapy / Q000517:prevention & control / Q000635:transmission; D026023:Permethrin / Q000009:adverse effects / Q000737:chemistry / Q000494:pharmacology
chemical_list: D056810:Acaricides; D007306:Insecticides; D010755:Organophosphates; D026023:Permethrin