title: Estimating the prevalence of active Helicobacter pylori infection in a rural community with global positioning system technology-assisted sampling.
abstract: We investigated a possible outbreak of H. pylori in a rural Northern Plains community. In a cross-sectional survey, we randomly sampled 244 households from a geocoded emergency medical system database. We used a complex survey design and global positioning system units to locate houses and randomly selected one eligible household member to administer a questionnaire and a 13C-urea breath test for active H. pylori infection (n = 166). In weighted analyses, active H. pylori infection was detected in 55·0% of the sample. Factors associated with infection on multivariate analysis included using a public drinking-water supply [odds ratio (OR) 12·2, 95% confidence interval (CI) 2·9-50·7] and current cigarette smoking (OR 4·1, 95% CI 1·7-9·6). People who lived in houses with more rooms, a possible indicator of decreased crowding in the home, were less likely to have active H. pylori infections (OR 0·7, 95% CI 0·5-0·9 for each additional room).
authors.affiliation: Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, GA, USA.
authors.forename: E J
authors.initials: EJ
authors.lastname: Melius
authors.affiliation: Division of Health Studies, Agency for Toxic Substances and Disease Registry, Atlanta, GA, USA.
authors.forename: S I
authors.initials: SI
authors.lastname: Davis
authors.affiliation: Division of Epidemiology and Disease Prevention, Office of Public Health Support, Indian Health Service, Albuquerque, NM, USA.
authors.forename: J T
authors.initials: JT
authors.lastname: Redd
authors.affiliation: Division of Health Studies, Agency for Toxic Substances and Disease Registry, Atlanta, GA, USA.
authors.forename: M
authors.initials: M
authors.lastname: Lewin
authors.affiliation: Johns Hopkins University School of Public Health, Baltimore, MD, USA.
authors.forename: R
authors.initials: R
authors.lastname: Herlihy
authors.affiliation: Division of Health Studies, Agency for Toxic Substances and Disease Registry, Atlanta, GA, USA.
authors.forename: A
authors.initials: A
authors.lastname: Henderson
authors.affiliation: Foodborne and Diarrheal Diseases Branch, Centers for Disease Control and Prevention, Atlanta, GA, USA.
authors.forename: J
authors.initials: J
authors.lastname: Sobel
authors.affiliation: Foodborne and Diarrheal Diseases Branch, Centers for Disease Control and Prevention, Atlanta, GA, USA.
authors.forename: B
authors.initials: B
authors.lastname: Gold
authors.affiliation: Division of Epidemiology and Disease Prevention, Office of Public Health Support, Indian Health Service, Albuquerque, NM, USA.
authors.forename: J E
authors.initials: JE
authors.lastname: Cheek
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001944:Breath Tests; D002648:Child; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D004196:Disease Outbreaks; D060766:Drinking Water; D005260:Female; D040362:Geographic Information Systems; D006306:Health Surveys / Q000379:methods*; D016481:Helicobacter Infections / Q000208:ethnology* / Q000382:microbiology; D016480:Helicobacter pylori; D006801:Humans; D007198:Indians, North American; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012424:Rural Population / Q000706:statistics & numerical data*; D012494:Sampling Studies; D014481:United States / Q000453:epidemiology; D055815:Young Adult
chemical_list: D060766:Drinking Water