title: Validate of clinical risk index for osteoporosis in Thai women at Phramongkutklao Hospital.
abstract: BACKGROUND
  Osteoporosis is a common problem found in elderly people and the cost of treatment with its complications is much higher than the cost of diagnosis and prevention. However diagnosis of osteoporosis is hindered by an unavailability of dual energy x-ray absorptiometry (DXA). Many clinical risk index-scoring systems were developed to help prediction of osteoporosis such as Khon Kaen Osteoporosis Study (KKOS). The KKOS is one among those scoring systems based on the Thai population database. The objectives of the present study were to validate KKOS for prediction of osteoporosis in Thai women at Gynecologic Clinic of Phramongkutklao Hospital and to study the prevalence of women with osteoporosis diagnosed with KKOS.
  
  
  METHODS
  Four hundred forty six Thai women, aged 40 years or more attending the Gynecologic Clinic of Phramongkutklao Hospital, and had Bone mineral density (BMD) result were enrolled in the present study. The results of BMD were measured at the lumbar spine and femoral neck by DXA and KKOS. The score was evaluated and compared.
  
  
  RESULTS
  Sensitivity and specificity of KKOS for prediction of osteoporosis were 48.6% and 68.1%, respectively. Prevalence of osteoporosis using KKOS was 23% while 32% were diagnosed with DXA.
  
  
  CONCLUSIONS
  KKOS had low sensitivity and specificity for diagnosed osteoporosis in Thai women at Gynecologic Clinic of Phramongkutklao Hospital.
authors.affiliation: Department of Obstetrics and Gynecology, Phramongkutklao Hospital, Bangkok, Thailand.
authors.forename: Ekachai
authors.initials: E
authors.lastname: Leeangkoonsathian
authors.forename: Pongrak
authors.initials: P
authors.lastname: Boonyanuruk
authors.forename: Chatlert
authors.initials: C
authors.lastname: Pongchaiyakul
authors.forename: Suthee
authors.initials: S
authors.lastname: Panichkul
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D001835:Body Weight; D015519:Bone Density; D015331:Cohort Studies; D005260:Female; D006305:Health Status Indicators; D006785:Hospitals, University; D006801:Humans; D008875:Middle Aged; D010024:Osteoporosis / Q000175:diagnosis* / Q000209:etiology; D011237:Predictive Value of Tests; D018570:Risk Assessment; D013785:Thailand