title: Struma ovarii with follicular thyroid-type carcinoma and neuroendocrine component: case report.
abstract: Struma ovarii (SO) is a slow-growing ovarian neoplasm with thyroid tissue as its predominant component. It is an uncommon neoplasm, usually asymptomatic with an unknown risk of malignant transformation. Due to difficulties in assessing the rare biological nature and the discrepancies in the reported cases, a consensus on the appropriate treatment has not been definitively reached. A 50-year-old female was subjected to upper gut endoscopy which showed a 30-mm mass located in the gastric antrum, suggestive of mesenchimal tumor. Incidentally, a pelvic CT scan also documented a solid mass in the right adnexa, with morphological characteristics of ovarian neoplasm. The patient underwent gastrectomy, total hysterectomy, bilateral salpingo-oophorectomy with lymph node dissection, and omentectomy. Histology documented the presence of gastric cavernous angioma, and, in the right adnexa, foci of follicular thyroid-type carcinoma arising in SO with a well-differentiated neuroendocrine component.Here we report and discuss the clinical and morphological presentation of follicular thyroid-type carcinoma arising in SO. The neoplasm was discovered incidentally and had a favorable clinical outcome at 1-year follow-up.
authors.affiliation: Unit of General and Laparoscopic Surgery, Biomedical Sciences Department, "G. d'Annunzio" University, Via dei Vestini 31, Chieti 66100, Italy.
authors.forename: Federico
authors.initials: F
authors.lastname: Selvaggi
authors.forename: Domenico
authors.initials: D
authors.lastname: Risio
authors.forename: Mathew
authors.initials: M
authors.lastname: Waku
authors.forename: Daniela
authors.initials: D
authors.lastname: Simo
authors.forename: Domenico
authors.initials: D
authors.lastname: Angelucci
authors.forename: Alberto
authors.initials: A
authors.lastname: D'Aulerio
authors.forename: Roberto
authors.initials: R
authors.lastname: Cotellese
authors.forename: Paolo
authors.initials: P
authors.lastname: Innocenti
mesh_terms: D018263:Adenocarcinoma, Follicular / Q000175:diagnosis*; D005260:Female; D006392:Hemangioma, Cavernous / Q000175:diagnosis*; D006801:Humans; D033162:Incidental Findings; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis*; D018358:Neuroendocrine Tumors / Q000175:diagnosis*; D010051:Ovarian Neoplasms / Q000175:diagnosis*; D013274:Stomach Neoplasms / Q000175:diagnosis*; D013330:Struma Ovarii / Q000175:diagnosis*