title: The surgical management of severe macroglossia in systemic AL amyloidosis.
abstract: Amyloidosis is a disease characterised by the deposition in body tissues of amyloid: abnormal protein in a beta pleated sheet formation. It is a systemic disorder and macroglossia may be seen in all forms. Changes to the normal architecture of the tissues and systemic features of the disease and its underlying cause can complicate the surgical management of the enlarged tongue.
authors.affiliation: South Thames Cleft Service, Guys and St Thomas's Hospitals NHS Trust, London, United Kingdom. alicobb@yahoo.com
authors.forename: Alistair R M
authors.initials: AR
authors.lastname: Cobb
authors.forename: Raghu
authors.initials: R
authors.lastname: Boyapati
authors.forename: Donald Murray
authors.initials: DM
authors.lastname: Walker
authors.forename: David J
authors.initials: DJ
authors.lastname: Dunaway
authors.forename: Timothy W
authors.initials: TW
authors.lastname: Lloyd
mesh_terms: D000368:Aged; D000682:Amyloid / Q000032:analysis; D000686:Amyloidosis / Q000473:pathology / Q000601:surgery*; D005260:Female; D005927:Glossectomy / Q000379:methods; D006801:Humans; D008260:Macroglossia / Q000473:pathology / Q000601:surgery*; D012008:Recurrence; D013529:Surgical Wound Dehiscence / Q000209:etiology; D014059:Tongue / Q000473:pathology; D014945:Wound Healing / Q000502:physiology
chemical_list: D000682:Amyloid