title: The buccal gland of Lampetra japonica is a source of diverse bioactive proteins.
abstract: The parasitic phase lampreys (Lampetra japonica) are bloodsuckers in the marine, and their buccal gland secretion (lamphredin) contains various regulators such as anticoagulants, ion channel blockers, and immune suppressors like those from leeches, insects, ticks, vampire bats, and snakes. This review focuses on the functions and characteristics of the active proteins from the buccal gland of L. japonica for the first time, and provides new insights into the parasitic mechanisms of lampreys and the possibilities of developing drugs such as novel anticoagulants, thrombolytic agents, local anesthetics, and immunosuppressants.
authors.affiliation: School of Life Sciences, Liaoning Normal University, Dalian 116081, China.
authors.forename: Rong
authors.initials: R
authors.lastname: Xiao
authors.forename: Yue
authors.initials: Y
authors.lastname: Pang
authors.forename: Qing Wei
authors.initials: QW
authors.lastname: Li
mesh_terms: D000818:Animals; D005088:Exocrine Glands / Q000378:metabolism*; D007798:Lampreys / Q000378:metabolism*; D011506:Proteins / Q000378:metabolism*
chemical_list: D011506:Proteins