title: Population-based pediatric reference intervals for general clinical chemistry analytes on the Abbott Architect ci8200 instrument.
abstract: BACKGROUND
  Reference intervals are crucial decision-making tools aiding clinicians in differentiating between healthy and diseased populations. However, for children such values often are lacking or incomplete.
  
  
  METHODS
  Blood samples were obtained from 692 healthy children, aged 6 months to 18 years, recruited in daycare centers and schools. Twelve common general clinical chemistry analytes were measured on the Abbott Architect ci8200 platform; sodium, potassium, chloride, calcium, albumin-adjusted calcium, phosphate, magnesium, creatinine (Jaffe and enzymatic), cystatin C, urea and uric acid.
  
  
  RESULTS
  Age- and gender specific pediatric reference intervals were defined by calculating the 2.5th and 97.5th percentiles.
  
  
  CONCLUSIONS
  The data generated is primarily applicable to a Caucasian population when using the Abbott Architect platform, but could be used by any laboratory if validated for the local patient population.
authors.affiliation: Department of Medical Sciences, Clinical Chemistry, Uppsala University, Uppsala, Sweden. peter.ridefelt@medsci.uu.se
authors.forename: Peter
authors.initials: P
authors.lastname: Ridefelt
authors.forename: Mattias
authors.initials: M
authors.lastname: Aldrimer
authors.forename: Per-Olof
authors.initials: PO
authors.lastname: Rödöö
authors.forename: Frank
authors.initials: F
authors.lastname: Niklasson
authors.forename: Leif
authors.initials: L
authors.lastname: Jansson
authors.forename: Jan
authors.initials: J
authors.lastname: Gustafsson
authors.forename: Dan
authors.initials: D
authors.lastname: Hellberg
mesh_terms: D000293:Adolescent; D000367:Age Factors; D001774:Blood Chemical Analysis / Q000295:instrumentation* / Q000592:standards*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D012016:Reference Values; D012737:Sex Factors