title: Vascular anomalies in pediatrics.
abstract: Vascular tumors consist of lesions secondary to endothelial hyperplasia, incorporating both hemangiomas and less common pediatric vascular tumors. Vascular malformations arise by dysmorphogenesis and exhibit normal endothelial cell turnover. Some anomalies may incorporate multiple areas of the vascular tree. Use of this division has provided a clinically useful method of diagnosis and prognosis, as well as a guide to therapy. It is hoped that with continued investigation into the biology and pathogenesis of these lesions, a more comprehensive molecular classification will soon be developed.
authors.affiliation: Department of Surgery, Vascular Anomalies Center, Children's Hospital Boston, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA.
authors.forename: R Dawn
authors.initials: RD
authors.lastname: Fevurly
authors.forename: Steven J
authors.initials: SJ
authors.lastname: Fishman
mesh_terms: D002648:Child; D003937:Diagnosis, Differential; D006391:Hemangioma / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D006801:Humans; D008202:Lymphangioma / Q000175:diagnosis / Q000628:therapy; D044148:Lymphatic Abnormalities / Q000175:diagnosis / Q000628:therapy; D013684:Telangiectasis / Q000175:diagnosis / Q000628:therapy; D054079:Vascular Malformations / Q000175:diagnosis / Q000209:etiology / Q000628:therapy