title: [Cardiopulmonary Exercise Testing (CPET) in severe COPD--a multicentre comparison of two test protocols].
abstract: Cardiopulmonary exercise testing (CPET) allows a valid evaluation of cardiopulmonary function capability and the recognition of existing limitations in COPD patients. Whereas the measurement of the different parameters of CPET and the evaluation of the results are standardised, this does not apply to the protocols chosen. The aim of this study was to evaluate whether the results of two different exercise protocols were comparable in an outpatient multicentre setting. Ninety COPD patients stages II-IV according to the Gold classification were examined by means of symptom-limited exercise testing on a bicycle with two different ramp protocols (10 Watts vs. 16 Watts/min) within seven days. The results show that a higher acceleration rate of the load was associated with shorter exercise duration and higher achieved exercise capacity. Gas exchange and ventilatory parameters did not show significant differences on comparing both protocols. In pulmonary practices COPD patients of the Gold stages II-IV can be examined safely and with validity by means of CPET. The application of a ramp protocol with a stepwise increase of 16 Watts/minute can be recommended, particularly as for this regimen standardised normal values are available.
authors.affiliation: Ernst-Moritz-Arndt-Universität Greifswald, Universitätsmedizin Greifswald, Klinik für Innere Medizin B, Greifswald. ewert@uni-greifswald.de
authors.forename: R
authors.initials: R
authors.lastname: Ewert
authors.forename: S
authors.initials: S
authors.lastname: Gläser
authors.forename: J
authors.initials: J
authors.lastname: Winkler
authors.forename: H
authors.initials: H
authors.lastname: Schrader
authors.forename: B G
authors.initials: BG
authors.lastname: Trümper
authors.forename: P-U
authors.initials: PU
authors.lastname: Haase
authors.forename: A
authors.initials: A
authors.lastname: Obst
authors.forename: G
authors.initials: G
authors.lastname: Hoheisel
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005080:Exercise Test / Q000706:statistics & numerical data*; D005260:Female; D005858:Germany / Q000453:epidemiology; D006334:Heart Function Tests / Q000706:statistics & numerical data*; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D029424:Pulmonary Disease, Chronic Obstructive / Q000175:diagnosis* / Q000453:epidemiology*; D015203:Reproducibility of Results; D012129:Respiratory Function Tests / Q000706:statistics & numerical data*; D012680:Sensitivity and Specificity