title: Surgical management of gastrointestinal basidiobolomycosis in pediatric patients.
abstract: BACKGROUND
  Gastrointestinal basidiobolomycosis (GIB) is a rare fungal disease. We reviewed our experience with this disease over the last 10 years, with special emphasis on the surgical aspects.
  
  
  METHODS
  A retrospective chart review was conducted for pediatric patients with GIB who were managed at our institution over the last 10 years. Demographic, clinical, and follow-up data were collected, and descriptive data were generated.
  
  
  RESULTS
  Nine patients with a median age of 7 years were managed for GIB over the study period. Six patients were managed surgically. Four had colonic and liver involvement, 1 had a left hepatic lesion, and 1 had a porta hepatic mass. One patient had multiple liver lesions and was managed medically, and 2 patients had disseminated disease and died shortly after presentation. Tissue biopsies confirmed the diagnosis, and all received antifungal treatment. Patients were followed up for a median of 6 years. All live patients are free of disease, and 4 are still on antifungal medications.
  
  
  CONCLUSIONS
  Gastrointestinal basidiobolomycosis is an aggressive disease that requires early surgical intervention to avoid complications and hasten disease eradication. Long-term follow-up is warranted, given the significant potential for complications.
authors.affiliation: King Faisal Specialist Hospital and Research Center, PO Box 3354, MBC 40, Riyadh 11211, Saudi Arabia. saud132@hotmail.com
authors.forename: Saud
authors.initials: S
authors.lastname: Al-Shanafey
authors.forename: Faten
authors.initials: F
authors.lastname: AlRobean
authors.forename: Ibrahim
authors.initials: I
authors.lastname: Bin Hussain
mesh_terms: D000935:Antifungal Agents / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D003082:Colectomy; D003108:Colonic Diseases / Q000188:drug therapy / Q000382:microbiology / Q000401:mortality / Q000601:surgery*; D003131:Combined Modality Therapy; D020091:Entomophthorales; D005260:Female; D005500:Follow-Up Studies; D006498:Hepatectomy; D006801:Humans; D017964:Itraconazole / Q000627:therapeutic use; D008107:Liver Diseases / Q000188:drug therapy / Q000382:microbiology / Q000401:mortality / Q000601:surgery*; D008297:Male; D012189:Retrospective Studies; D016896:Treatment Outcome; D020096:Zygomycosis / Q000188:drug therapy / Q000401:mortality / Q000601:surgery*
chemical_list: D000935:Antifungal Agents; D017964:Itraconazole