title: Highly efficient intramolecular Cannizzaro reaction between 1,3-distal formyl groups at the upper rim of a cone-calix[4]arene.
abstract: The 1,3-distal cone-calix[4]arene dialdehyde 1 undergoes Cannizzaro disproportionation in the presence of strong base, but its 1,2-vicinal regioisomer 3 and the analogous monoaldehyde 2 are unreactive under the same conditions. The high intramolecular reactivity of the 1,3-distal regioisomer 1 is measured and discussed in terms of Effective Molarity (EM).
authors.affiliation: Dipartimento di Chimica and IMC/CNR, Università La Sapienza, P.le A. Moro 5, 00185 Rome, Italy.
authors.forename: Marzia
authors.initials: M
authors.lastname: Galli
authors.forename: José Augusto
authors.initials: JA
authors.lastname: Berrocal
authors.forename: Stefano
authors.initials: S
authors.lastname: Di Stefano
authors.forename: Roberta
authors.initials: R
authors.lastname: Cacciapaglia
authors.forename: Luigi
authors.initials: L
authors.lastname: Mandolini
authors.forename: Laura
authors.initials: L
authors.lastname: Baldini
authors.forename: Alessandro
authors.initials: A
authors.lastname: Casnati
authors.forename: Franco
authors.initials: F
authors.lastname: Ugozzoli