title: Primary malignant melanoma of proximal tibia.
abstract: Primary malignant melanoma (clear cell sarcoma) of bone is a very rare neoplasm. Although metastatic melanoma to bone is not uncommon, primary malignant melanoma of bone is extremely uncommon. To date, only nine cases have been reported in the English literature. In this report, we present a case of primary malignant melanoma arising from the medial aspect of the proximal tibia in a 26-year-old woman. We treated the patient with above-knee amputation without any chemotherapy or radiotherapy. At final follow-up of 18 months, the patient was free of disease.
authors.affiliation: Department of Orthopedics, PGIMER, Chandigarh, India.
authors.forename: Aditya K
authors.initials: AK
authors.lastname: Mootha
authors.forename: Kamal
authors.initials: K
authors.lastname: Bali
authors.forename: Vishal
authors.initials: V
authors.lastname: Kumar
authors.forename: Saurabh
authors.initials: S
authors.lastname: Rawall
authors.forename: Raghav
authors.initials: R
authors.lastname: Saini
authors.forename: Mandeep S
authors.initials: MS
authors.lastname: Dhillon
mesh_terms: D000328:Adult; D001859:Bone Neoplasms / Q000175:diagnosis* / Q000378:metabolism / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D007719:Knee Joint / Q000000981:diagnostic imaging; D008545:Melanoma / Q000175:diagnosis* / Q000378:metabolism / Q000473:pathology / Q000601:surgery*; D058950:Melanoma-Specific Antigens / Q000378:metabolism; D011859:Radiography; D009418:S100 Proteins / Q000378:metabolism; D013977:Tibia; D058951:gp100 Melanoma Antigen
chemical_list: D058950:Melanoma-Specific Antigens; C548637:PMEL protein, human; D009418:S100 Proteins; D058951:gp100 Melanoma Antigen