title: Can chemotherapy cause cancer relapse?
abstract: Deep whole-genome sequencing of primary tumors in acute myeloid leukemia has revealed evidence that chemotherapy can lead to new mutations that may drive resistance.
mesh_terms: D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000009:adverse effects; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000188:drug therapy* / Q000235:genetics* / Q000473:pathology; D009154:Mutation / Q000187:drug effects; D009364:Neoplasm Recurrence, Local / Q000235:genetics* / Q000473:pathology
chemical_list: D000970:Antineoplastic Agents