title: Association between parity and obesity in Mexican and Mexican-American women: findings from the Ella binational breast cancer study.
abstract: Obesity at diagnosis of breast cancer is associated with higher all-cause mortality and treatment-associated toxicities. We evaluated the association between parity and obesity in the Ella study, a population of Mexican and Mexican-American breast cancer patients with high parity. Obesity outcomes included body mass index (BMI) ≥30 kg/m(2), waist circumference (WC) ≥35 in (88 cm), and waist-to-hip-ratio (WHR) ≥0.85. Prevalence of obesity ([BMI] ≥ 30 kg/m(2)) was 38.9 %. For WC, the multivariate odds ratio (OR) (95 % confidence interval [CI]) for having WC ≥ 35 inches in women with ≥4 pregnancies relative to those with 1-2 pregnancies was 1.59 (1.01-2.47). Higher parity (≥4 pregnancies) was non-significantly associated with high BMI (OR = 1.10; 95 % CI 0.73-1.67). No positive association was observed for WHR. Our results suggest WC is independently associated with high parity in Hispanic women and may be an optimal target for post-partum weight loss interventions.
authors.affiliation: Moores UCSD Cancer Center, University of California, San Diego, 3855 Health Sciences Drive, #0901, La Jolla, CA 92093-0901, USA. e8martinez@ucsd.edu
authors.forename: María Elena
authors.initials: ME
authors.lastname: Martínez
authors.forename: Erika
authors.initials: E
authors.lastname: Pond
authors.forename: Betsy C
authors.initials: BC
authors.lastname: Wertheim
authors.forename: Jesse N
authors.initials: JN
authors.lastname: Nodora
authors.forename: Elizabeth T
authors.initials: ET
authors.lastname: Jacobs
authors.forename: Melissa
authors.initials: M
authors.lastname: Bondy
authors.forename: Adrian
authors.initials: A
authors.lastname: Daneri-Navarro
authors.forename: Maria Mercedes
authors.initials: MM
authors.lastname: Meza-Montenegro
authors.forename: Luis Enrique
authors.initials: LE
authors.lastname: Gutierrez-Millan
authors.forename: Abenaa
authors.initials: A
authors.lastname: Brewster
authors.forename: Ian K
authors.initials: IK
authors.lastname: Komenaka
authors.forename: Patricia
authors.initials: P
authors.lastname: Thompson
mesh_terms: D005260:Female; D006801:Humans; D017058:Mexican Americans; D008800:Mexico; D008875:Middle Aged; D009765:Obesity / Q000208:ethnology*; D010298:Parity; D011247:Pregnancy; D014481:United States; D055105:Waist Circumference