title: Subcutaneous Panniculitis-Like T-Cell Lymphoma (SPTL) in a Child with Spontaneous Resolution.
abstract: Subcutaneous panniculitis-like T-cell lymphomas (SPTLs) α/β are rare in childhood. The present report refers to a case of a 7-year-old male child presenting an extensive skin lesion that began when he was 5 years of age. Two biopsies were evaluated using the CD3, CD4, CD8, CD56, βF1, and TIA markers. A dense infiltrate of CD3+, CD4-, CD8+, CD56-, βF1+, and TIA+ pleomorphic lymphocytes was found in the subcutis. The previous biopsy showed cytophagic histiocytic panniculitis with a small focus on CD8+ and βF1+ malignant cells. The lesion regressed spontaneously. This case shows that prognosis may be excellent in SPTL (α/β). On the other hand, it also serves as an alert that a biopsy performed in an area of cytophagic panniculitis may lead to misdiagnosis.
authors.affiliation: Department of Pathology, Complexo Hospitalar Universitário Prof. Edgard Santos, Federal University of Bahia, Salvador, BA, Brazil.
authors.forename: Achiléa L
authors.initials: AL
authors.lastname: Bittencourt
authors.forename: Maria das Graças Silva
authors.initials: Md
authors.lastname: Vieira
authors.forename: Eny Guimarães
authors.initials: EG
authors.lastname: Carvalho
authors.forename: Celeste
authors.initials: C
authors.lastname: Cunha
authors.forename: Iguaracyra
authors.initials: I
authors.lastname: Araujo