title: A facile method for the synthesis of N-(α-aminoacyl) sulfonamides.
abstract: N-Acylsulfonamide derivatives have important applications in organic synthesis and drug discovery. It was found that many problems occurred preparing amino acid derived N-acylsulfonamides with the commonly used coupling approach in our previous studies. In this paper, we report an efficient approach to synthesize various amino acids derived N-acylsulfonamides in high yields without any racemization.
authors.affiliation: School of Pharmacy, Shandong University, Ji'nan, Shandong, China.
authors.forename: S L
authors.initials: SL
authors.lastname: Wu
authors.forename: M L
authors.initials: ML
authors.lastname: Chen
authors.forename: Y T
authors.initials: YT
authors.lastname: Wang
authors.forename: X B
authors.initials: XB
authors.lastname: Hou
authors.forename: X Y
authors.initials: XY
authors.lastname: Yang
authors.forename: L
authors.initials: L
authors.lastname: Su
authors.forename: H
authors.initials: H
authors.lastname: Fang
mesh_terms: D000596:Amino Acids / Q000737:chemistry; D000812:Anhydrides / Q000737:chemistry; D060326:Chemistry Techniques, Synthetic / Q000379:methods*; D013449:Sulfonamides / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D000596:Amino Acids; D000812:Anhydrides; D013449:Sulfonamides