title: Aspirin: a history, a love story.
abstract: Most pharmacists know that aspirin's origins lie with willow bark, but they may be unaware of its role in the development of the pharmaceutical industry. Evolving from salacin (the active ingredient in many plant remedies) to salicylic acid (an analgesic in its own right) to the more effective, less toxic acetylsalicylic acid, this pain reliever cornered the nonsteroidal anti-inflammatory market for more than 70 years. It helped the dye industry branch into pharmaceuticals, and is now used in multiple indications.
authors.affiliation: University of Connecticut School of Pharmacy, Storrs, CT, USA.
authors.forename: Jeannette Y
authors.initials: JY
authors.lastname: Wick
mesh_terms: D000700:Analgesics / Q000266:history*; D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects / Q000266:history* / Q000627:therapeutic use; D001241:Aspirin / Q000009:adverse effects / Q000266:history* / Q000627:therapeutic use; D001592:Benzyl Alcohols / Q000737:chemistry; D002318:Cardiovascular Diseases / Q000517:prevention & control; D004342:Drug Hypersensitivity; D004351:Drug Resistance; D005960:Glucosides / Q000737:chemistry; D049671:History, 18th Century; D049672:History, 19th Century; D049673:History, 20th Century; D006801:Humans; D009369:Neoplasms / Q000517:prevention & control; D032108:Salix / Q000737:chemistry; D012727:Sex Characteristics
chemical_list: D000700:Analgesics; D000894:Anti-Inflammatory Agents, Non-Steroidal; D001592:Benzyl Alcohols; D005960:Glucosides; C005696:salicin; D001241:Aspirin