title: Analyzing intact proteins with mass spectrometry.
abstract: A new top-down method of identifying intact proteins is particularly suited to differentiating highly related protein species created by alternative splicing, proteolytic events, and post-translational modifications.
mesh_terms: D017398:Alternative Splicing; D002853:Chromatography, Liquid / Q000379:methods; D006367:HeLa Cells; D006801:Humans; D013058:Mass Spectrometry / Q000379:methods*; D011499:Protein Processing, Post-Translational; D011506:Proteins / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism; D059748:Proteolysis
chemical_list: D011506:Proteins