title: Unusual localizations of sentinel lymph nodes in early stage cervical cancer: a review.
abstract: OBJECTIVE
  The aim of this study was to systematically determine the frequency of unusual localizations of sentinel lymph node in patients with early stage cervical cancer.
  
  
  METHODS
  We performed a comprehensive computer literature search of English and French language studies in human subjects on sentinel node procedures in PUBMED database up to December 2010. For each article two reviewers independently performed data extraction using a standard form to determine the route of unusual lymphatic spread of sentinel procedures in cervical cancer.
  
  
  RESULTS
  According to our search, 83.7% of detected sentinel lymph nodes in patients with cervical cancer were in expected localizations (i.e., external iliac, obturator, internal iliac or interiliac). The unusual localizations were: 6.6% in the common iliac chain, 4.31% parametrial, 1.26% sacral, 2% in the lower para-aortic area and 0.07% in the inguinal chain.
  
  
  CONCLUSIONS
  The unusual localizations of sentinel lymph nodes impose to the gynecologic surgeons to be able to perform lymph node dissection in all the territories potentially affected.
authors.affiliation: Department of Gynecology, Tours University Hospitals, France. l.ouldamer@chu-tours.fr
authors.forename: Lobna
authors.initials: L
authors.lastname: Ouldamer
authors.forename: Henri
authors.initials: H
authors.lastname: Marret
authors.forename: Olivier
authors.initials: O
authors.lastname: Acker
authors.forename: Isabelle
authors.initials: I
authors.lastname: Barillot
authors.forename: Gilles
authors.initials: G
authors.lastname: Body
mesh_terms: D005260:Female; D006801:Humans; D008197:Lymph Node Excision / Q000379:methods; D008198:Lymph Nodes / Q000473:pathology*; D008207:Lymphatic Metastasis; D021701:Sentinel Lymph Node Biopsy; D002583:Uterine Cervical Neoplasms / Q000473:pathology*