title: Right upper quadrant pain and mass in a 41-year-old previously healthy man: a presenting feature of HIV-associated extranodal diffuse large B cell lymphoma with cardiac involvement.
abstract: With an increasing pandemic of HIV/AIDS, the incidence of HIV-associated lymphoma is expected to rise. Here, the authors report a case of a 41-year-old man who presented with right upper quadrant pain and mass, and was subsequently diagnosed with HIV-associated diffuse large B cell lymphoma (DLBCL) with cardiac involvement. This case illustrates some of the uncommon and interesting aspects of DLBCL: primary extramedullary extranodal stage IV disease as the presenting feature; cardiac involvement at presentation; DLBCL as the only clue to the diagnosis of HIV; and management of HIV-associated DLBCL. This case is also a reminder of the importance of the routine HIV screening for all patients between the ages of 13-64 years, as advocated by centres of disease control and prevention.
authors.affiliation: Department of Haematology/Oncology, Staten Island University Hospital, Staten Island, New York, USA.
authors.forename: Abhirami
authors.initials: A
authors.lastname: Vivekanandarajah
authors.forename: Vijaya Raj
authors.initials: VR
authors.lastname: Bhatt
authors.forename: Balakumar
authors.initials: B
authors.lastname: Krishnarasa
authors.forename: Srujitha
authors.initials: S
authors.lastname: Murukutla
authors.forename: Arnold
authors.initials: A
authors.lastname: Brenner
authors.forename: Shilpi
authors.initials: S
authors.lastname: Gupta
mesh_terms: D015746:Abdominal Pain / Q000175:diagnosis*; D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D023241:Antiretroviral Therapy, Highly Active; D003520:Cyclophosphamide / Q000627:therapeutic use; D003937:Diagnosis, Differential; D003952:Diagnostic Imaging; D004317:Doxorubicin / Q000627:therapeutic use; D006338:Heart Neoplasms / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D016483:Lymphoma, AIDS-Related / Q000175:diagnosis* / Q000188:drug therapy; D016403:Lymphoma, Large B-Cell, Diffuse / Q000175:diagnosis* / Q000188:drug therapy; D008297:Male; D011241:Prednisone / Q000627:therapeutic use; D014750:Vincristine / Q000627:therapeutic use
chemical_list: D014750:Vincristine; D004317:Doxorubicin; D003520:Cyclophosphamide; D011241:Prednisone