title: [Use of cannabis and psychopathological risk in onset psychosis].
abstract: OBJECTIVE
  The aim of the study is to assess the correlations between cannabis use and psychopathological features, disorder severity and global functioning in subjects with onset psychosis (schizophrenic and bipolar psychosis) and at risk mental state.
  
  
  METHODS
  Sixty-seven consecutive subjects with diagnosis of bipolar spectrum disorder (N=49), schizophrenic spectrum disorder (N=5) and at risk mental state (N=13) were recruited from the SMILE (Service for Monitoring and early Intervention Looking at the fight against the onset of mental Even psychological youths' suffering). All subjects were assessed with the Self Report Symptom Inventory-90 (SCL-90), the Global Assessment of Functioning scale (GAF) and Clinical Global Impressions-Severity (CGI-S). Moreover, they were assessed for the cannabis use in the last month.
  
  
  RESULTS
  The total sample was splitted in two groups: Group 1 of cannabis use subjects (N=30) and Group 2 of no cannabis use subjects (N=37). Group 1 subjects showed significant higher scores at psychoticism SCL-90 dimension and at CGI-S than Group 2 subjects. The higher scores at anger/hostility and psychoticism SCL-90 dimensions and at CGI-S seem to be discriminant features of Group 1 cannabis use subjects.
  
  
  CONCLUSIONS
  The data reported suggest that cannabis use assessment in onset psychosis (bipolar and schizophrenic onset) and at risk mental state could add clinical information to the psychopathological and diagnostic description. Such information should be ''incorporated'' in the treatment choice model and outcome prediction assessment.
authors.affiliation: Universita di L' Aquila.
authors.forename: Annarita
authors.initials: A
authors.lastname: Tomassini
authors.forename: Rita
authors.initials: R
authors.lastname: Roncone
authors.forename: Laura
authors.initials: L
authors.lastname: Verni
authors.forename: Roberta
authors.initials: R
authors.lastname: Ortenzi
authors.forename: Giuditta
authors.initials: G
authors.lastname: Di Melchiorre
authors.forename: Adele
authors.initials: A
authors.lastname: Tosone
authors.forename: Massimo
authors.initials: M
authors.lastname: Casacchia
authors.forename: Rocco
authors.initials: R
authors.lastname: Pollice
mesh_terms: D000328:Adult; D017668:Age of Onset; D000465:Algorithms; D001714:Bipolar Disorder / Q000175:diagnosis* / Q000628:therapy; D061345:Early Medical Intervention; D005260:Female; D006801:Humans; D008297:Male; D002189:Marijuana Abuse; D010555:Personality Inventory; D011569:Psychiatric Status Rating Scales; D011618:Psychotic Disorders / Q000175:diagnosis* / Q000628:therapy; D012306:Risk; D012494:Sampling Studies; D012559:Schizophrenia / Q000175:diagnosis* / Q000628:therapy; D012720:Severity of Illness Index