title: Antibacterial evaluation of some Schiff bases derived from 2-acetylpyridine and their metal complexes.
abstract: A series of Schiff bases derived from 2-acetylpyridne and their metal complexes were characterized by elemental analysis, NMR, FT-IR and UV-Vis spectral studies. The complexes were screened for anti-bacterial activity against Methicillin-resistant Staphylococcus aureus (MRSA), Acinetobacter baumanni (AC), Klebsiella pneumonie (KB) and Pseudomonas aeruginosa (PA) using the disc diffusion and micro broth dilution assays. Based on the overall results, the complexes showed the highest activities against MRSA while a weak antibacterial activity was observed against A. baumanii and P. aeruginosa.
authors.affiliation: Chemistry Department, Faculty of Science, University of Malaya, Kuala Lumpur 50603, Malaysia. nura_suleiman@yahoo.com
authors.forename: Nura Suleiman
authors.initials: NS
authors.lastname: Gwaram
authors.forename: Hapipah Mohd
authors.initials: HM
authors.lastname: Ali
authors.forename: Hamid
authors.initials: H
authors.lastname: Khaledi
authors.forename: Mahmood Ameen
authors.initials: MA
authors.lastname: Abdulla
authors.forename: A Hamid A
authors.initials: AH
authors.lastname: Hadi
authors.forename: Thong Kwai
authors.initials: TK
authors.lastname: Lin
authors.forename: Chai Lay
authors.initials: CL
authors.lastname: Ching
authors.forename: Cher Lin
authors.initials: CL
authors.lastname: Ooi
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects*; D056831:Coordination Complexes / Q000737:chemistry*; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D011725:Pyridines / Q000737:chemistry*; D012545:Schiff Bases / Q000737:chemistry / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D056831:Coordination Complexes; D011725:Pyridines; D012545:Schiff Bases; C543930:2-acetylpyridine