title: Total synthesis of (-)-dysiherbaine.
abstract: The enantioselective synthesis of (-)-dysiherbaine (1) has been established with efficiency via a unique synthetic strategy involving the desymmetrization of 2-substituted glycerol to install a quaternary chiral carbon, which induces further stereochemistry in the bicyclic perhydrofuropyran through mercuriocyclization and epoxidation.
authors.affiliation: MIRC, Dept. of Chemistry, KAIST, Daejeon 305-701, Korea.
authors.forename: Nelma Carurucan
authors.initials: NC
authors.lastname: Celindro
authors.forename: Tae Woo
authors.initials: TW
authors.lastname: Kim
authors.forename: Sung Ho
authors.initials: SH
authors.lastname: Kang
mesh_terms: D000409:Alanine / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry; D019086:Bridged Bicyclo Compounds, Heterocyclic / Q000138:chemical synthesis* / Q000737:chemistry; D008968:Molecular Conformation; D013237:Stereoisomerism
chemical_list: D019086:Bridged Bicyclo Compounds, Heterocyclic; C121741:dysiherbaine; D000409:Alanine