title: Lung transplant infection.
abstract: Lung transplantation has become an accepted therapeutic procedure for the treatment of end-stage pulmonary parenchymal and vascular disease. Despite improved survival rates over the decades, lung transplant recipients have lower survival rates than other solid organ transplant recipients. The morbidity and mortality following lung transplantation is largely due to infection- and rejection-related complications. This article will review the common infections that develop in the lung transplant recipient, including the general risk factors for infection in this population, and the most frequent bacterial, viral, fungal and other less frequent opportunistic infections. The epidemiology, diagnosis, prophylaxis, treatment and outcomes for the different microbial pathogens will be reviewed. The effects of infection on lung transplant rejection will also be discussed.
authors.affiliation: Department of Medicine, Division of Pulmonary Diseases and Critical Care Medicine, University of Texas Health Science Center at San Antonio, Texas 78229-3900, USA.
authors.forename: Sergio R
authors.initials: SR
authors.lastname: Burguete
authors.forename: Diego J
authors.initials: DJ
authors.lastname: Maselli
authors.forename: Juan F
authors.initials: JF
authors.lastname: Fernandez
authors.forename: Stephanie M
authors.initials: SM
authors.lastname: Levine
mesh_terms: D001424:Bacterial Infections / Q000453:epidemiology / Q000209:etiology; D006084:Graft Rejection / Q000453:epidemiology* / Q000382:microbiology*; D006801:Humans; D008168:Lung / Q000382:microbiology*; D008171:Lung Diseases / Q000601:surgery*; D016040:Lung Transplantation / Q000009:adverse effects*; D009181:Mycoses / Q000453:epidemiology / Q000209:etiology; D011183:Postoperative Complications / Q000453:epidemiology* / Q000382:microbiology*; D012307:Risk Factors; D014777:Virus Diseases / Q000453:epidemiology / Q000209:etiology