title: Role of a point-of-care protease activity diagnostic test in Canadian clinical practice: a Canadian expert consensus ©.
abstract: Nonhealing wounds (stalled, healable) challenge affected individuals, wound clinicians, and society. Nonhealing may result despite local factors being corrected. The interplay between tissue degradation, increased inflammatory response, and abundant protease activity is a challenging quandary. A modified Delphi process was utilized to investigate a protease activity test and practice implications.
authors.affiliation: Public Health and Medicine, University of Toronto, Ontario, Canada.
authors.forename: R Gary
authors.initials: RG
authors.lastname: Sibbald
authors.forename: Robert J
authors.initials: RJ
authors.lastname: Snyder
authors.forename: Mariam
authors.initials: M
authors.lastname: Botros
authors.forename: Cathy
authors.initials: C
authors.lastname: Burrows
authors.forename: Patricia
authors.initials: P
authors.lastname: Coutts
authors.forename: Lincoln
authors.initials: L
authors.lastname: D'Souza
authors.forename: Janet
authors.initials: J
authors.lastname: Kuhnke
authors.forename: Chantal
authors.initials: C
authors.lastname: Labrecque
authors.forename: Karen
authors.initials: K
authors.lastname: Laforet
authors.forename: Stephan
authors.initials: S
authors.lastname: Landis
authors.forename: Kimberly
authors.initials: K
authors.lastname: LeBlanc
authors.forename: Vincent
authors.initials: V
authors.lastname: Maida
authors.forename: Christine
authors.initials: C
authors.lastname: Pearson
authors.forename: Michele
authors.initials: M
authors.lastname: Suitor
authors.forename: Richard
authors.initials: R
authors.lastname: Belley
authors.forename: Sowmil
authors.initials: S
authors.lastname: Mehta
mesh_terms: D000465:Algorithms; D002170:Canada; D032921:Consensus; D003697:Delphi Technique; D003955:Diagnostic Tests, Routine / Q000295:instrumentation* / Q000379:methods; D006801:Humans; D007249:Inflammation / Q000175:diagnosis / Q000201:enzymology / Q000473:pathology; D010447:Peptide Hydrolases / Q000032:analysis* / Q000378:metabolism; D019095:Point-of-Care Systems; D013997:Time Factors; D014945:Wound Healing; D014947:Wounds and Injuries / Q000175:diagnosis* / Q000378:metabolism / Q000473:pathology
chemical_list: D010447:Peptide Hydrolases