title: Catalytic asymmetric sulfenylation of unprotected 3-substituted oxindoles.
abstract: Catalytic asymmetric sulfenylation of unprotected 3-substituted oxindoles has been developed via cooperative catalysis of a chiral N,N'-dioxide-Sc(OTf)(3) complex and a Brønsted base. Utilizing readily available N-(phenylthio)phthalimide as the sulfur source, a wide range of optically active 3-phenylthiooxindoles were obtained in excellent yields with excellent enantioselectivities under mild reaction conditions.
authors.affiliation: Key Laboratory of Green Chemistry & Technology, Ministry of Education, College of Chemistry, Sichuan University, Chengdu 610064, P. R. China.
authors.forename: Yunfei
authors.initials: Y
authors.lastname: Cai
authors.forename: Jun
authors.initials: J
authors.lastname: Li
authors.forename: Weiliang
authors.initials: W
authors.lastname: Chen
authors.forename: Mingsheng
authors.initials: M
authors.lastname: Xie
authors.forename: Xiaohua
authors.initials: X
authors.lastname: Liu
authors.forename: Lili
authors.initials: L
authors.lastname: Lin
authors.forename: Xiaoming
authors.initials: X
authors.lastname: Feng
mesh_terms: D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry; D008698:Mesylates / Q000737:chemistry; D015394:Molecular Structure; D000078183:Oxindoles; D012538:Scandium / Q000737:chemistry; D013237:Stereoisomerism; D013438:Sulfhydryl Compounds / Q000737:chemistry*
chemical_list: D007211:Indoles; D008698:Mesylates; D000078183:Oxindoles; D013438:Sulfhydryl Compounds; C436603:scandium triflate; C022960:2-oxindole; D012538:Scandium