title: Mechanistic analysis of gold(I)-catalyzed intramolecular allene hydroalkoxylation reveals an off-cycle bis(gold) vinyl species and reversible C-O bond formation.
abstract: Mechanistic investigation of gold(I)-catalyzed intramolecular allene hydroalkoxylation established a mechanism involving rapid and reversible C-O bond formation followed by turnover-limiting protodeauration from a mono(gold) vinyl complex. This on-cycle pathway competes with catalyst aggregation and formation of an off-cycle bis(gold) vinyl complex.
authors.affiliation: French Family Science Center, Duke University, Durham, North Carolina 27708-0346, United States.
authors.forename: Timothy J
authors.initials: TJ
authors.lastname: Brown
authors.forename: Dieter
authors.initials: D
authors.lastname: Weber
authors.forename: Michel R
authors.initials: MR
authors.lastname: Gagné
authors.forename: Ross A
authors.initials: RA
authors.lastname: Widenhoefer
mesh_terms: D002384:Catalysis; D005663:Furans / Q000138:chemical synthesis* / Q000737:chemistry; D006046:Gold / Q000737:chemistry*; D008958:Models, Molecular; D015394:Molecular Structure; D013011:Sorbic Acid / Q000031:analogs & derivatives* / Q000737:chemistry*
chemical_list: D005663:Furans; C018674:tetrahydrofuran; D006046:Gold; D013011:Sorbic Acid