title: WNTs in synapse formation and neuronal circuitry.
abstract: Wnt proteins play important roles in wiring neural circuits. Wnts regulate many aspects of neural circuit generation through their receptors and distinct signalling pathways. In this review, we discuss recent findings on the functions of Wnts in various aspects of neural circuit formation, including neuronal polarity, axon guidance, synapse formation, and synaptic plasticity in vertebrate and invertebrate nervous systems.
authors.affiliation: Center for Functional Connectomics, Brain Science Institute, Seoul, Korea. mpark@kist.re.kr
authors.forename: Mikyoung
authors.initials: M
authors.lastname: Park
authors.forename: Kang
authors.initials: K
authors.lastname: Shen
mesh_terms: D000818:Animals; D005786:Gene Expression Regulation; D006801:Humans; D008954:Models, Biological; D009474:Neurons / Q000502:physiology*; D015398:Signal Transduction; D013569:Synapses / Q000502:physiology*; D051153:Wnt Proteins / Q000378:metabolism*
chemical_list: D051153:Wnt Proteins