title: [Epidemiology and clinical implications of carbapenemase-producing bacteria in Switzerland].
abstract: The emergence and global dissemination of carbapenemases represents a major threat to public health. Switzerland has not been spared; we report a case-series of four patients hospitalised in our institution colonised with carbapenemase-producing bacteria. Infections caused by carbapenemase-producing Enterobacteriaceae limit therapeutic options and increase mortality. Detection of carbapenemases is also a challenge for laboratories. It is imperative to implement stringent infection control measures in order to prevent epidemics at the hospital level.
authors.affiliation: Service de Médicine Interne, HUG Genève. mohamed.abbas@hcuge.ch
authors.forename: M
authors.initials: M
authors.lastname: Abbas
authors.forename: A
authors.initials: A
authors.lastname: Cherkaoui
authors.forename: C
authors.initials: C
authors.lastname: Fankhauser
authors.forename: J
authors.initials: J
authors.lastname: Schrenzel
authors.forename: S
authors.initials: S
authors.lastname: Harbarth
mesh_terms: D000328:Adult; D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism*; D017714:Community-Acquired Infections / Q000175:diagnosis / Q000453:epidemiology / Q000635:transmission; D024901:Drug Resistance, Multiple, Bacterial / Q000235:genetics; D004755:Enterobacteriaceae / Q000235:genetics / Q000378:metabolism* / Q000472:pathogenicity / Q000502:physiology; D004756:Enterobacteriaceae Infections / Q000175:diagnosis* / Q000453:epidemiology* / Q000635:transmission; D005260:Female; D006801:Humans; D007194:India; D008297:Male; D008954:Models, Biological; D010154:Pakistan; D010360:Patient Transfer; D011379:Prognosis; D013557:Switzerland; D014195:Travel; D001618:beta-Lactamases / Q000235:genetics / Q000378:metabolism*
chemical_list: D001426:Bacterial Proteins; D001618:beta-Lactamases; C063912:carbapenemase