title: Trends in invasive infection with methicillin-resistant Staphylococcus aureus, Connecticut, USA, 2001-2010.
abstract: We examined trends in incidence of methicillin-resistant Staphylococcus aureus (MRSA) infections in Connecticut, with emphasis on 2007-2010, after legislation required reporting of hospital infections. A case was defined as isolation of MRSA from normally sterile body sites, classified after medical record review as hospital onset (HO), community onset, health care-associated community onset (HACO), or community-associated (CA). Blood isolates collected during 2005-2010 were typed and categorized as community- or health care-related strains. During 2001-2010, a total of 8,758 cases were reported (58% HACO, 31% HO, and 11% CA), and MRSA incidence decreased (p<0.05) for HACO and HO, but increased for CA. Significant 3- to 4-year period trends were decreases in all MRSA (-18.8%), HACO (-12.8%), HO (-33.2%), and CA (-12.7%) infections during 2007-2010, and an increase in CA infections during 2004-2006. Decreases in health care-related isolates accounted for all reductions. Hospital infections reporting may have catalyzed the decreases.
authors.affiliation: Yale University School of Public Health, New Haven, CT 06511, USA. hadler-epi@att.net
authors.forename: James L
authors.initials: JL
authors.lastname: Hadler
authors.forename: Susan
authors.initials: S
authors.lastname: Petit
authors.forename: Mona
authors.initials: M
authors.lastname: Mandour
authors.forename: Matthew L
authors.initials: ML
authors.lastname: Cartter
mesh_terms: D000293:Adolescent; D000368:Aged; D016470:Bacteremia / Q000453:epidemiology* / Q000382:microbiology; D002648:Child; D017714:Community-Acquired Infections / Q000453:epidemiology* / Q000382:microbiology; D003237:Connecticut / Q000453:epidemiology; D003428:Cross Infection / Q000453:epidemiology* / Q000382:microbiology; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D055624:Methicillin-Resistant Staphylococcus aureus; D008875:Middle Aged; D018571:Sentinel Surveillance; D013203:Staphylococcal Infections / Q000453:epidemiology* / Q000382:microbiology