title: Ruthenium-catalyzed redox isomerization of trifluoromethylated allylic alcohols: mechanistic evidence for an enantiospecific pathway.
abstract: Transfer news: A synthetic approach to chiral β-CF(3)-substituted saturated carbonyl compounds has been developed in which ruthenium complexes efficiently catalyze the redox isomerization of CF(3)-bearing allylic alcohols by an intramolecular suprafacial enantiospecific 1,3-hydrogen transfer (see scheme). This method was used for the enantioselective synthesis of (S)-CF(3)-citronellol.
authors.affiliation: UMR CNRS 6014 C.O.B.R.A., Université et INSA de Rouen, 1 rue Tesnière, 76821 Mont Saint Aignan, France.
authors.forename: Vincent
authors.initials: V
authors.lastname: Bizet
authors.forename: Xavier
authors.initials: X
authors.lastname: Pannecoucke
authors.forename: Jean-Luc
authors.initials: JL
authors.lastname: Renaud
authors.forename: Dominique
authors.initials: D
authors.lastname: Cahard