title: Effect of houttuynia cordata aetherolea on adiponectin and connective tissue growth factor in a rat model of diabetes mellitus.
abstract: OBJECTIVE
  To determine the effect of Houttuynia cordata Aetherolea on connective tissue growth factor and adiponectin in a rat model of diabetes mellitus (DM).
  
  
  METHODS
  DM was induced in rats using streptozotocin (STZ) and high glucose-lipid animal feed. Animals were then treated with Houttuynia cordata Aetherolea for 8 weeks. Changes in connective tissue growth factor and adiponectin levels in rats were observed.
  
  
  RESULTS
  Connective tissue growth factor and adiponectin levels in rats with DM improved after Houttuynia cordata Aetherolea treatment.
  
  
  CONCLUSIONS
  Houttuynia cordata Aetherolea had a positive effect on rats with DM by reducing levels of connective tissue growth factor and increasing adiponectin levels.
authors.affiliation: Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China. wanghaiying_7@hotmail.com
authors.forename: Hai-Ying
authors.initials: HY
authors.lastname: Wang
authors.forename: Jun-Lu
authors.initials: JL
authors.lastname: Bao
mesh_terms: D052242:Adiponectin / Q000235:genetics / Q000378:metabolism*; D000818:Animals; D055513:Connective Tissue Growth Factor / Q000235:genetics / Q000378:metabolism*; D003920:Diabetes Mellitus / Q000188:drug therapy* / Q000235:genetics / Q000378:metabolism; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage*; D052859:Houttuynia / Q000737:chemistry*; D006801:Humans; D008297:Male; D051381:Rats; D017208:Rats, Wistar
chemical_list: D052242:Adiponectin; D004365:Drugs, Chinese Herbal; D055513:Connective Tissue Growth Factor