title: Approach to STEMI and NSTEMI.
abstract: Acute coronary syndrome (ACS) refers to any constellation of clinical symptoms that are compatible with acute myocardial ischemia. ACS is divided into ST- elevated myocardial infarction (STEMI), non-ST elevated myocardial infarction (NSTEMI), and unstable angina (UA). STEMI results from complete and prolonged occlusion of an epicardial coronary blood vessel and is defined based on ECG criteria..NSTEMI usually results from severe coronary artery narrowing, transient occlusion, or microembolization of thrombus and/or atheromatous material. NSTEMI is defined by an elevation of cardiac biomarkers in the absence of ST elevation. The syndrome is termed UA in the absence of elevated cardiac enzymes. History, physical examination, ECG, biochemical markers, ECHO all remain important tools to make an appropriate diagnosis The management of ACS should focus on rapid diagnosis, risk stratification, and institution of therapies that restore coronary blood flow and reduce myocardial ischemia.
authors.affiliation: Fortis Escorts Heart Institute and Research Center, Okhla Road, New Delhi- 100028.
authors.forename: Lal C
authors.initials: LC
authors.lastname: Daga
authors.forename: Upendra
authors.initials: U
authors.lastname: Kaul
authors.forename: Aijaz
authors.initials: A
authors.lastname: Mansoor
mesh_terms: D000700:Analgesics / Q000627:therapeutic use; D000789:Angina, Unstable / Q000175:diagnosis* / Q000628:therapy*; D015415:Biomarkers; D002637:Chest Pain / Q000209:etiology; D017023:Coronary Angiography; D042241:Early Diagnosis; D004452:Echocardiography; D004562:Electrocardiography; D019317:Evidence-Based Medicine; D005343:Fibrinolytic Agents / Q000627:therapeutic use; D006801:Humans; D009203:Myocardial Infarction / Q000175:diagnosis* / Q000628:therapy*; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use; D018570:Risk Assessment; D012307:Risk Factors; D012720:Severity of Illness Index; D015912:Thrombolytic Therapy / Q000379:methods; D013997:Time Factors; D016896:Treatment Outcome; D014665:Vasodilator Agents / Q000627:therapeutic use
chemical_list: D000700:Analgesics; D015415:Biomarkers; D005343:Fibrinolytic Agents; D010975:Platelet Aggregation Inhibitors; D014665:Vasodilator Agents