title: Clinical evaluation of urine Histoplasma capsulatum antigen measurement in cats with suspected disseminated histoplasmosis.
abstract: Diagnosis of Histoplasma capsulatum infection in cats traditionally relies upon identification of organisms in circulating monocytes or in tissue specimens from affected organs. In this retrospective study, results of a urine antigen assay were compared with standard diagnostic methods in cats with clinical signs suggestive of histoplasmosis. Antigenuria was detected in 17/18 cats with a histopathologic or cytopathologic diagnosis of histoplasmosis. This preliminary evaluation of the Histoplasma urine antigen test suggests it may be a useful aid in diagnosing this disease in cats.
authors.affiliation: Department of Small Animal Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX 77843, USA. akcook@cvm.tamu.edu
authors.forename: Audrey K
authors.initials: AK
authors.lastname: Cook
authors.forename: Lauren Y
authors.initials: LY
authors.lastname: Cunningham
authors.forename: Annette K
authors.initials: AK
authors.lastname: Cowell
authors.forename: L Joseph
authors.initials: LJ
authors.lastname: Wheat
mesh_terms: D000818:Animals; D000946:Antigens, Fungal / Q000652:urine*; D002371:Cat Diseases / Q000175:diagnosis / Q000652:urine*; D002415:Cats; D019411:Clinical Laboratory Techniques / Q000379:methods; D005260:Female; D006658:Histoplasma / Q000302:isolation & purification*; D006660:Histoplasmosis / Q000175:diagnosis / Q000652:urine* / Q000662:veterinary*; D008297:Male; D012189:Retrospective Studies
chemical_list: D000946:Antigens, Fungal