title: Five year incidence of visual field loss in adult Chinese. The Beijing Eye Study.
abstract: OBJECTIVE
  To describe the cumulative 5 year incidence of visual field loss in adult Chinese in Greater Beijing.
  
  
  METHODS
  The Beijing Eye Study 2006 included 3251 subjects (mean age 60.4±10.1 years) who had participated in the Beijing Eye Study 2001 and returned for re-examination. All participants underwent a comprehensive eye examination, including visual field test by frequency doubling threshold perimetry. An abnormal visual field was defined as reduced sensitivity in at least one test location. Incident visual field loss was defined as a change in visual field from normal at baseline to abnormal at follow-up.
  
  
  RESULTS
  An incident visual field loss was detected in 273 eyes (4.3±0.5%)/235 subjects (7.3±0.5%). It was significantly associated with higher age (P = 0.001), higher intraocular pressure (P<0.001), and higher fasting blood glucose concentration (P = 0.019). Considering only eyes (n = 140) with a detected cause for visual field loss, the most frequent causes were cataract (68 (48.6%) eyes) followed by glaucoma (23 (16.4%) eyes), diabetic retinopathy (13 (9.3%) eyes), age-related macular degeneration (10 (7.1%) eyes), and myopic degenerative retinopathy (9 (6.4%) eyes). For 133 (48.7%) eyes with a visual field loss, the cause for the VFL remained unclear.
  
  
  CONCLUSIONS
  The 5-year incidence of visual field loss was 4.3±0.5% per eye or 7.3±0.5% per subject. It increased significantly with age, intraocular pressure, and fasting blood glucose level. Major causes for the incidence of visual field loss were cataract, glaucoma and diabetic retinopathy.
authors.affiliation: Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
authors.forename: Ya Xing
authors.initials: YX
authors.lastname: Wang
authors.forename: Liang
authors.initials: L
authors.lastname: Xu
authors.forename: Xiu Ying
authors.initials: XY
authors.lastname: Sun
authors.forename: Yang
authors.initials: Y
authors.lastname: Zou
authors.forename: Hai Tao
authors.initials: HT
authors.lastname: Zhang
authors.forename: Jost B
authors.initials: JB
authors.lastname: Jonas
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D044466:Asian People; D001786:Blood Glucose; D002681:China / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D016015:Logistic Models; D008875:Middle Aged; D014786:Vision Disorders / Q000453:epidemiology* / Q000209:etiology; D058609:Visual Field Tests / Q000379:methods; D014794:Visual Fields / Q000502:physiology*
chemical_list: D001786:Blood Glucose