title: Targeting NF-κB in mouse models of lung adenocarcinoma.
abstract: Xue et al. demonstrate response and increased survival but development of acquired resistance to proteasome and inhibitor-κB kinase inhibitors targeting NF-κB activation in adenocarcinomas of Kras-activated, p53-deficient mice.
authors.affiliation: Head and Neck Surgery Branch, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, Maryland 20892, USA. vanwaesc@nidcd.nih.gov
authors.forename: Carter
authors.initials: C
authors.lastname: Van Waes
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy*; D000077192:Adenocarcinoma of Lung; D000818:Animals; D000970:Antineoplastic Agents / Q000494:pharmacology*; D008175:Lung Neoplasms / Q000188:drug therapy*; D016328:NF-kappa B / Q000037:antagonists & inhibitors*
chemical_list: D000970:Antineoplastic Agents; D016328:NF-kappa B