title: Asexuals, polyploids, evolutionary opportunists...: the population genetics of positive but deteriorating mutations.
abstract: Some genetic phenomena originate as mutations that are initially advantageous but decline in fitness until they become distinctly deleterious. Here I give the condition for a mutation-selection balance to form and describe some of the properties of the resulting equilibrium population. A characterization is also given of the fixation probabilities for such mutations.
authors.affiliation: Department of Biology, Evolutionary Genetics, Lund University, SE-223 62 Lund, Sweden. bengt_olle.bengtsson@biol.lu.se
authors.forename: Bengt O
authors.initials: BO
authors.lastname: Bengtsson
mesh_terms: D000465:Algorithms; D019143:Evolution, Molecular; D056084:Genetic Fitness; D005828:Genetics, Population; D008957:Models, Genetic; D009154:Mutation; D011123:Polyploidy; D012100:Reproduction, Asexual / Q000235:genetics*; D012641:Selection, Genetic