title: Considerations for importing live genetically modified mice from academic laboratories.
abstract: Genetically modified mice have been an invaluable tool for the study of gene function in an intact biological system. Researchers frequently obtain genetically modified mice from other academic institutions. This form of collaboration between laboratories comes with a unique set of challenges, and a clear set of guidelines for navigating the process has yet to be defined. The author provides suggestions for how to initiate an exchange of animal resources and steps for ensuring a successful collaboration. Both parties should be clear about their expectations. The importing lab should prepare in advance for potential animal health considerations and breeding and colony management strategies prior to importation. The number, gender, age and genotype of the imported animals should be confirmed as soon as possible by the importing lab. It is in the best interest of all parties to be courteous, forthright and thorough when sharing animal resources so that everyone can benefit from the resulting research.
authors.affiliation: Department of Neuroscience, Weill Cornell Graduate School of Medical Sciences, Cornell University, New York, NY, USA. Jat2020@med.cornell.edu
authors.forename: Jennifer A
authors.initials: JA
authors.lastname: Tyson
mesh_terms: D000827:Animal Welfare; D000818:Animals; D000830:Animals, Laboratory; D001947:Breeding; D003299:Cooperative Behavior; D007753:Laboratories; D051379:Mice; D008822:Mice, Transgenic