title: Structural biology: How opioid drugs bind to receptors.
authors.forename: Marta
authors.initials: M
authors.lastname: Filizola
authors.forename: Lakshmi A
authors.initials: LA
authors.lastname: Devi
mesh_terms: D000818:Animals; D040761:Biomimetic Materials / Q000737:chemistry*; D006801:Humans; D009019:Morphinans / Q000737:chemistry*; D009271:Naltrexone / Q000031:analogs & derivatives* / Q000737:chemistry; D018847:Opioid Peptides / Q000737:chemistry*; D010880:Piperidines / Q000737:chemistry* / Q000378:metabolism*; D011957:Receptors, Opioid / Q000737:chemistry* / Q000378:metabolism*; D017465:Receptors, Opioid, delta / Q000737:chemistry*; D017473:Receptors, Opioid, kappa / Q000037:antagonists & inhibitors* / Q000737:chemistry*; D017450:Receptors, Opioid, mu / Q000037:antagonists & inhibitors* / Q000737:chemistry*; D013141:Spiro Compounds / Q000737:chemistry* / Q000378:metabolism*; D044005:Tetrahydroisoquinolines / Q000737:chemistry*; D000094942:Nociceptin Receptor
chemical_list: C479838:(Nphe(1),Arg(14),Lys(15))N-OFQ NH(2); C543193:1-benzyl-N-(3-(spiroisobenzofuran-1(3H),4'-piperidin-1-yl)propyl)pyrrolidine-2-carboxamide; C433814:7-hydroxy-N-(1-((4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinyl)methyl)-2-methylpropyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide; D009019:Morphinans; D018847:Opioid Peptides; D010880:Piperidines; D011957:Receptors, Opioid; D017465:Receptors, Opioid, delta; D017473:Receptors, Opioid, kappa; D017450:Receptors, Opioid, mu; D013141:Spiro Compounds; D044005:Tetrahydroisoquinolines; D009271:Naltrexone; C055382:naltrindole; D000094942:Nociceptin Receptor; C000722283:OPRL1 protein, human