title: Bipolar disorder is associated with HIV transmission risk behavior among patients in treatment for HIV.
abstract: This study examined HIV transmission risk behavior among 63 patients with bipolar disorder (BD), major depressive disorder, and no mood disorder; half had substance use disorders (SUDs). Patients with BD were more likely than others to report unprotected intercourse with HIV-negative partners and <95 % adherence to antiretroviral medications. In multivariate models, BD and SUD were independent predictors of both risk behaviors. Participants with poorer medication adherence were more likely to have detectable HIV viral loads and unprotected intercourse with HIV-negative partners. Patients with BD deserve careful evaluation and HIV prevention services to reduce HIV transmission risk behaviors.
authors.affiliation: Department of Psychiatry & Behavioral Sciences, Duke University School of Medicine, Box 90519, Durham, NC, 27708, USA. christina.meade@duke.edu
authors.forename: Christina S
authors.initials: CS
authors.lastname: Meade
authors.forename: Lisa A
authors.initials: LA
authors.lastname: Bevilacqua
authors.forename: Mary D
authors.initials: MD
authors.lastname: Key
mesh_terms: D000328:Adult; D000368:Aged; D019380:Anti-HIV Agents / Q000627:therapeutic use*; D001714:Bipolar Disorder / Q000150:complications / Q000523:psychology*; D018791:CD4 Lymphocyte Count; D016022:Case-Control Studies; D003865:Major Depressive Disorder / Q000150:complications / Q000523:psychology; D005260:Female; D015658:HIV Infections / Q000188:drug therapy* / Q000523:psychology / Q000635:transmission*; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D008297:Male; D055118:Medication Adherence / Q000523:psychology; D008875:Middle Aged; D019964:Mood Disorders / Q000150:complications / Q000523:psychology; D011569:Psychiatric Status Rating Scales; D012307:Risk Factors; D012309:Risk-Taking; D012747:Sexual Partners; D019966:Substance-Related Disorders / Q000150:complications / Q000523:psychology; D047568:Unsafe Sex / Q000523:psychology / Q000706:statistics & numerical data; D019562:Viral Load; D055815:Young Adult; D016903:Drug Monitoring
chemical_list: D019380:Anti-HIV Agents