title: Epidemiology of canine distemper virus in wild raccoon dogs (Nyctereutes procyonoides) from South Korea.
abstract: Raccoon dogs (Nyctereutes procyonoides) are widespread and common in South Korea. In 2011, we obtained serum samples from 102 wild raccoon dogs to survey their exposure to canine distemper virus (CDV). Forty-five of the 102 animals (44.1%) were seropositive. Field cases of canine distemper in wild raccoon dogs from 2010 to 2011 were investigated. Fourteen cases of CDV infection were identified by a commercially available CDV antigen detection kit. These cases were used for virus isolation and molecular analysis. Sequence analysis of hemagglutinin genes indicated that all viruses isolated belonged to the Asia-2 genotype. H protein residues which are related to the receptor and host specificity (residues 530 and 549) were analyzed. A glutamic acid (E) residue is present at 530 in all isolates. At 549, a histidine (H) residue was found in five isolates and tyrosine (Y) residue was found in 6 isolates. Our study demonstrated that CDV infection was widespread in wild raccoon dogs in South Korea.
authors.affiliation: Department of Infectious Diseases, College of Veterinary Medicine and Korea Zoonosis Research Institute, Chonbuk National University, Chonbuk, South Korea.
authors.forename: Se-Yeoun
authors.initials: SY
authors.lastname: Cha
authors.forename: Eun-Ju
authors.initials: EJ
authors.lastname: Kim
authors.forename: Min
authors.initials: M
authors.lastname: Kang
authors.forename: Sang-Ho
authors.initials: SH
authors.lastname: Jang
authors.forename: Hae-Beom
authors.initials: HB
authors.lastname: Lee
authors.forename: Hyung-Kwan
authors.initials: HK
authors.lastname: Jang
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D000956:Antigens, Viral / Q000032:analysis; D004216:Distemper / Q000453:epidemiology* / Q000821:virology; D004217:Distemper Virus, Canine / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D019143:Evolution, Molecular; D005814:Genes, Viral; D005838:Genotype; D006389:Hemagglutinins, Viral / Q000032:analysis / Q000235:genetics; D008969:Molecular Sequence Data; D010802:Phylogeny; D046031:Raccoon Dogs / Q000821:virology*; D011933:Reagent Kits, Diagnostic; D056910:Republic of Korea / Q000453:epidemiology
chemical_list: D000956:Antigens, Viral; D006389:Hemagglutinins, Viral; D011933:Reagent Kits, Diagnostic