title: Comparison of Humphrey Matrix frequency doubling technology to standard automated perimetry in neuro-ophthalmic disease.
abstract: OBJECTIVE
  We compared Humphrey Matrix FDT 30-2 (FDT) and Humphrey Visual Field Analyzer 30-2 SITA standard (SAP) in the assessment of anterior (optic nerve or chiasm) and posterior (retro-chiasmal) afferent visual pathway defects.
  
  
  METHODS
  In this retrospective comparative study, the charts of 37 patients (16 males, range 13-84 years, mean 72.1), with neuro-ophthalmic visual field defects who were tested with both FDT and SAP, were reviewed. Two masked graders assessed the concordance and extent of field defects between the perimeters. The mean concordance between anterior and posterior disease was compared using the Wilcoxon rank sum test. The mean deviation (MD) and pattern standard deviation (PSD) of each perimeter were correlated with the Spearman coefficient.
  
  
  RESULTS
  Twenty-eight patients had anterior and nine had posterior disease. Most had a fair or good concordance (89.3% anterior, 88.9% posterior). When comparing anterior to posterior disease, the mean concordance of the defects of the two parameters was not statistically different (P = 0.94 and P = 0.61 for total deviation and pattern deviation, respectively). The MD and PSD between perimeters had a significant correlation.
  
  
  CONCLUSIONS
  Our series, using 30-2 field analysis, demonstrates fair to good correlation between FDT and SAP in the majority of patients. In roughly 10% findings between FDT and SAP were discordant. This difference was similar for anterior and posterior disease.
authors.affiliation: Department of Ophthalmology, University of California San Francisco, San Francisco, California, USA.
authors.forename: Michael K
authors.initials: MK
authors.lastname: Yoon
authors.forename: Thomas N
authors.initials: TN
authors.lastname: Hwang
authors.forename: Shelley
authors.initials: S
authors.lastname: Day
authors.forename: Jenny
authors.initials: J
authors.lastname: Hong
authors.forename: Travis
authors.initials: T
authors.lastname: Porco
authors.forename: Timothy J
authors.initials: TJ
authors.lastname: McCulley
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006423:Hemianopsia / Q000175:diagnosis* / Q000209:etiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009901:Optic Nerve Diseases / Q000150:complications / Q000175:diagnosis*; D015203:Reproducibility of Results; D012189:Retrospective Studies; D058609:Visual Field Tests / Q000379:methods*; D014794:Visual Fields; D055815:Young Adult