title: Circulating endothelial progenitors and tumor resistance to vascular-targeting therapies.
abstract: Acute mobilization of circulating endothelial progenitors has been implicated in tumor resistance to vascular-disrupting agents. In the current issue of Cancer Discovery, Taylor and colleagues provide novel insight into the kinetics of endothelial progenitor mobilization by vascular-disrupting agents in both mouse tumor models and cancer patients.
authors.affiliation: The Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, Swiss Federal Institute of Technology Lausanne (EPFL), Lausanne, Switzerland. michele.depalma@epfl.ch
authors.forename: Michele
authors.initials: M
authors.lastname: De Palma
authors.forename: Silvia
authors.initials: S
authors.lastname: Nucera
mesh_terms: D020533:Angiogenesis Inhibitors / Q000494:pharmacology*; D000818:Animals; D019008:Drug Resistance, Neoplasm; D042783:Endothelial Cells / Q000187:drug effects*; D006801:Humans; D008297:Male; D013234:Stem Cells / Q000187:drug effects*
chemical_list: D020533:Angiogenesis Inhibitors