title: [Challenges in the early detection of psychosis in children and adolescents].
abstract: The early detection and treatment of persons at-risk for psychosis is currently regarded a promising strategy in fighting the devastating consequences of psychotic disorders. The two current at-risk approaches, i.e., the "ultra high risk" and the "basic symptom" criteria, were mainly developed on adult samples. Initial evidence suggests, however, that they cannot simply be applied to children and adolescents. For ultra high risk criteria, there is indication of some attenuated psychotic symptoms being potentially non-specific in adolescents and of brief limited intermittent symptoms being difficult to clinically classify in children when observable behavioral correlates are missing. For basic symptoms, too, only preliminary indication of their usefulness in children and adolescents exists. Since developmental peculiarities in the assessment of basic symptoms should be considered, a child and youth version of the Schizophrenia Proneness Instrument (SPI-CY) was developed. In conclusion, research on the clinical-prognostic validity of the at-risk criteria and their potential adoption to the special needs of children and adolescents is needed. If a Prodromal Risk Syndrome for Psychosis or Attenuated Psychotic Symptoms Syndrome will be included into DSM-V, it has to be highlighted that its suitability for children and adolescents is only insufficiently known.
authors.affiliation: Dipartimento di Neurologia, Sapienza Universita di Roma.
authors.forename: Paolo
authors.initials: P
authors.lastname: Fiori Nastro
authors.forename: Benno G
authors.initials: BG
authors.lastname: Schimmelmann
authors.forename: Eva
authors.initials: E
authors.lastname: Gebhardt
authors.forename: Elena
authors.initials: E
authors.lastname: Monducci
authors.forename: Franz
authors.initials: F
authors.lastname: Resch
authors.forename: Eginhard
authors.initials: E
authors.lastname: Koch
authors.forename: Frauke
authors.initials: F
authors.lastname: Schultze-Lutter
mesh_terms: D000293:Adolescent; D002648:Child; D003937:Diagnosis, Differential; D042241:Early Diagnosis; D006801:Humans; D011569:Psychiatric Status Rating Scales; D011618:Psychotic Disorders / Q000175:diagnosis* / Q000628:therapy; D012307:Risk Factors; D012559:Schizophrenia / Q000175:diagnosis* / Q000628:therapy; D012569:Schizotypal Personality Disorder / Q000175:diagnosis* / Q000628:therapy