title: Clinical research of acupoint application for "treatment of winter disease in summer" used to prevent and treat bronchial asthma in children.
abstract: OBJECTIVE
  To preliminarily analyze key factors influencing curative effect through clinical observations of acupoint application for "treatment of winter disease in summer" used to prevent and treat bronchial asthma in children.
  
  
  METHODS
  In an observational study and prospective cohort study, we observed children in remission of asthma at three class III grade A TCM hospitals in Liaoning, Hubei, and Chengdu.
  
  
  RESULTS
  A total of 609 children conformed to diagnostic and inclusive standards for remission of bronchial asthma. Through follow-up visits, we observed their skin reactions and the time and chance of treatment with different therapies in the three hospitals; we also compared and analyzed different drugs, acupoints, and preparations. We found that the key Chinese drugs were Bai Jie Zi (Semen Sinapis Albae) and Yian Hu Suo (Rhizoma Corydalis); the key acupoints were Feishu (BL 13), Gaohuang (BL 43), Dingchuan (EX-B1), Tiantu (CV 22), and Shanzhong (CV 17); and the best preparation was a mixture of drugs, ginger juice, and musk. Acupoint application was practiced on the hottest days of summer and the coldest days of winter for 0.5 to 2 h with the lowest rate of asthma relapse.
  
  
  CONCLUSIONS
  The present data analysis shows that the curative effect of acupoint application for "treatment of winter disease in summer" may be influenced by recipes of Chinese drugs, preparations, prescriptions of acupoints, chance, time, and skin reactions. A curative effect is the result of the comprehensive action of these factors.
authors.affiliation: Chinese Acupuncture Association, Beijing 100700, China.
authors.forename: Bi-Ling
authors.initials: BL
authors.lastname: Wen
authors.forename: Bao-Yan
authors.initials: BY
authors.lastname: Liu
authors.forename: Peng
authors.initials: P
authors.lastname: Jin
authors.forename: Xue-Feng
authors.initials: XF
authors.lastname: Wang
authors.forename: Xi-Xiong
authors.initials: XX
authors.lastname: Xiang
authors.forename: Xiao-Fan
authors.initials: XF
authors.lastname: Liu
authors.forename: Jing-Qing
authors.initials: JQ
authors.lastname: Hu
authors.forename: Fang
authors.initials: F
authors.lastname: Lu
authors.forename: Li-Yun
authors.initials: LY
authors.lastname: He
authors.forename: Wen-Zeng
authors.initials: WZ
authors.lastname: Zhu
authors.forename: Yi-Gong
authors.initials: YG
authors.lastname: Fang
authors.forename: Yu
authors.initials: Y
authors.lastname: Wang
mesh_terms: D015669:Acupuncture Points; D000293:Adolescent; D001249:Asthma / Q000188:drug therapy* / Q000517:prevention & control*; D002648:Child; D002675:Child, Preschool; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D011446:Prospective Studies; D012621:Seasons; D016896:Treatment Outcome
chemical_list: D004365:Drugs, Chinese Herbal