title: Laryngeal stenosis in a patient with severe congenital neutropenia.
abstract: OBJECTIVE
  We report the first case of laryngeal stenosis with granuloma in a patient with severe congenital neutropenia (SCN).
  
  
  METHODS
  Case report and retrospective review.
  
  
  METHODS
  Review of medical records.
  
  
  RESULTS
  A 6-year-old female who was diagnosed with SCN presented with a cough and wheezing. An endoscopic study revealed laryngeal stenosis with granuloma. Tracheotomy and direct laryngoscopy were performed under general anesthesia, and administration of granulocyte colony-stimulating factor was started. The laryngeal granuloma disappeared 3 weeks later, and the tracheal stoma was closed.
  
  
  CONCLUSIONS
  Presence of a laryngeal lesion should be considered in SCN patients with persistent airway symptoms.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan. hbando@koto.kpu-m.ac.jp
authors.forename: Hideki
authors.initials: H
authors.lastname: Bando
authors.forename: Hikaru
authors.initials: H
authors.lastname: Nagao
authors.forename: Takeshi
authors.initials: T
authors.lastname: Nishio
authors.forename: Ryuichi
authors.initials: R
authors.lastname: Hirota
authors.forename: Hirofumi
authors.initials: H
authors.lastname: Sakaguchi
authors.forename: Toshihiko
authors.initials: T
authors.lastname: Imamura
authors.forename: Yasuo
authors.initials: Y
authors.lastname: Hisa
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001706:Biopsy; D002648:Child; D000080984:Congenital Bone Marrow Failure Syndromes; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D016179:Granulocyte Colony-Stimulating Factor / Q000627:therapeutic use; D006801:Humans; D007828:Laryngoscopy; D007829:Laryngostenosis / Q000150:complications* / Q000628:therapy*; D009503:Neutropenia / Q000150:complications / Q000151:congenital*; D014140:Tracheotomy
chemical_list: D000900:Anti-Bacterial Agents; D005938:Glucocorticoids; D016179:Granulocyte Colony-Stimulating Factor