title: Pheochromocytoma in multiple endocrine neoplasia type 2A: positive 123I MIBG with negative CT and equivocal 131I MIBG imaging.
abstract: An 123I metaiodobenzylguanidine (MIBG) planar image showed abnormal uptake in the left adrenal gland and thyroid in a 24-year-old woman with multiple endocrine neoplasia type 2A. 131I MIBG showed abnormal uptake in the thyroid but not in the adrenal gland. Abdominal CT with 2-mm thin slices demonstrated a normal adrenal gland. Postoperative pathologic findings were consistent with medullary carcinoma in both thyroid lobes and a small 1-mm pheochromocytoma in the left adrenal gland. 123I MIBG could clearly show the small pheochromocytoma, which was negative in thin-slice CT and equivocal in 131I MIBG.
authors.affiliation: Department of Radiology, Fukushima Medical University, Hikarigaoka, Fukushima, Japan. shirou@fmu.ac.jp
authors.forename: Shirou
authors.initials: S
authors.lastname: Ishii
authors.forename: Fumio
authors.initials: F
authors.lastname: Shishido
authors.forename: Masayuki
authors.initials: M
authors.lastname: Miyajima
authors.forename: Kotaro
authors.initials: K
authors.lastname: Sakuma
authors.forename: Ken
authors.initials: K
authors.lastname: Kikuchi
mesh_terms: D019797:3-Iodobenzylguanidine; D000310:Adrenal Gland Neoplasms / Q000150:complications* / Q000175:diagnosis* / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D009377:Multiple Endocrine Neoplasia / Q000150:complications*; D010673:Pheochromocytoma / Q000150:complications* / Q000175:diagnosis* / Q000000981:diagnostic imaging; D011877:Radionuclide Imaging; D014057:Tomography, X-Ray Computed; D055815:Young Adult
chemical_list: D019797:3-Iodobenzylguanidine