title: Synthesis of pyrido[2,3-b]indoles and pyrimidoindoles via Pd-catalyzed amidation and cyclization.
abstract: Biologically and pharmaceutically active core structures containing a new class of 4-hydroxy-α-carbolines, dihydropyrido[2,3-b]indoles, pyrimido[4,5-b] and [5,4-b]indoles have been synthesized in good yields via Pd-catalyzed amidation and cyclizations. The keto-enol tautomerism in 4-hydroxy-α-carbolines has been investigated by DFT calculations and spectroscopic techniques. The fluorescence studies of pyrimido[4,5-b] and [5,4-b]indoles were carried out with good quantum yields.
authors.affiliation: School of Chemistry, University of Hyderabad, Hyderabad-500046, India.
authors.forename: Arepalli Sateesh
authors.initials: AS
authors.lastname: Kumar
authors.forename: P V Amulya
authors.initials: PV
authors.lastname: Rao
authors.forename: Rajagopal
authors.initials: R
authors.lastname: Nagarajan
mesh_terms: D000577:Amides / Q000138:chemical synthesis / Q000737:chemistry; D002243:Carbolines / Q000138:chemical synthesis* / Q000737:chemistry; D003500:Cyclization; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry; D010165:Palladium / Q000737:chemistry*; D011743:Pyrimidines / Q000138:chemical synthesis / Q000737:chemistry
chemical_list: D000577:Amides; D002243:Carbolines; D007211:Indoles; D011743:Pyrimidines; D010165:Palladium