title: Reversible cerebral vasoconstriction syndrome induced by adrenaline.
abstract: BACKGROUND
  Reversible cerebral vasoconstriction syndrome (RCVS) is characterized by acute severe thunderclap headaches and evidence of multifocal, segmental, reversible vasoconstrictions of the cerebral arteries. Several precipitating factors have been identified and reported, including the use of recreational substances or sympathomimetic drugs and the postpartum state.
  
  
  METHODS
  Here we present the case of a woman who developed RCVS after the administration of adrenaline (epinephrine) in the setting of an anaphylactic reaction during antibiotic allergy testing.
  
  
  CONCLUSIONS
  To our knowledge, this is the first reported case of RCVS following the administration of exogenous adrenaline. This case contributes to the understanding of the physiopathological mechanisms underlying reversible cerebral vasoconstriction.
authors.affiliation: University Clinic of Navarra, Pamplona, Spain.
authors.forename: Jose-Alberto
authors.initials: JA
authors.lastname: Palma
authors.forename: Ariadna
authors.initials: A
authors.lastname: Fontes-Villalba
authors.forename: Pablo
authors.initials: P
authors.lastname: Irimia
authors.forename: Reyes
authors.initials: R
authors.lastname: Garcia-Eulate
authors.forename: Eduardo
authors.initials: E
authors.lastname: Martinez-Vila
mesh_terms: D000707:Anaphylaxis / Q000188:drug therapy; D001993:Bronchodilator Agents / Q000009:adverse effects*; D004837:Epinephrine / Q000009:adverse effects*; D005260:Female; D051270:Headache Disorders, Primary / Q000139:chemically induced* / Q000503:physiopathology; D006801:Humans; D008875:Middle Aged; D013577:Syndrome; D014661:Vasoconstriction; D020301:Vasospasm, Intracranial / Q000139:chemically induced* / Q000503:physiopathology
chemical_list: D001993:Bronchodilator Agents; D004837:Epinephrine