title: A novel one-pot pseudo-five-component condensation reaction towards bifunctional diazepine-tetrazole containing compounds: synthesis of 1H-tetrazolyl-1H-1,4-diazepine-2,3-dicarbonitriles and 1H-tetrazolyl-benzo[b][1,4]diazepines.
abstract: A novel and efficient method has been developed for the one-pot synthesis of bifunctional diazepine-tetrazole containing compounds. 1H-Tetrazolyl-1H-1,4-diazepine-2, 3-dicarbonitrile and 1H-tetrazolyl-benzo[b][1,4]diazepine derivatives were synthesized in good yields using 2,3-diaminomaleonitrile or an aromatic diamine, ketones, trimethylsilyl azide, and an isocyanide in the presence of p-toluenesulfonic acid as a catalyst in methanol at room temperature.
authors.affiliation: Department of Chemistry, Shahid Beheshti University, Tehran, Iran.
authors.forename: Hamid
authors.initials: H
authors.lastname: Mofakham
authors.forename: Ahmad
authors.initials: A
authors.lastname: Shaabani
authors.forename: Sajjad
authors.initials: S
authors.lastname: Mousavifaraz
authors.forename: Fatemeh
authors.initials: F
authors.lastname: Hajishaabanha
authors.forename: Shabnam
authors.initials: S
authors.lastname: Shaabani
authors.forename: Seik Weng
authors.initials: SW
authors.lastname: Ng
mesh_terms: D001381:Azepines / Q000138:chemical synthesis* / Q000737:chemistry*; D015394:Molecular Structure; D009570:Nitriles / Q000138:chemical synthesis* / Q000737:chemistry; D013777:Tetrazoles / Q000737:chemistry
chemical_list: D001381:Azepines; D009570:Nitriles; D013777:Tetrazoles; C045574:1H-tetrazole