title: A malignant granular cell tumor excised with mohs micrographic surgery.
abstract: Malignant granular cell tumors are extremely rare, aggressive neoplasms displaying rapid growth and frequent associated metastatic disease. Excision and evaluation for metastatic disease are mandatory. We present a 54-year-old patient with a malignant granular cell tumor, treated with Mohs micrographic surgery. Cutaneous granular cell tumors are uncommon neoplasms, likely of perineural origin. Most follow a benign and uneventful course, with wide local excision being the treatment of choice (Enzinger, 1988). The malignant granular cell tumor is an extremely rare, aggressive variant, which provides a diagnostic challenge and management dilemma, especially with early presentation when it may be mistaken for other entities. There is also controversy regarding surgical management and follow-up of both benign and malignant granular cell tumors.
authors.affiliation: Department of Dermatology, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA.
authors.forename: David
authors.initials: D
authors.lastname: Crowe
authors.forename: Elias E
authors.initials: EE
authors.lastname: Ayli
authors.forename: Hugh M
authors.initials: HM
authors.lastname: Gloster