title: The structure of common and uncommon mental disorders.
abstract: BACKGROUND
  Co-morbidity patterns in epidemiological studies of mental illness consistently demonstrate that a latent internalizing factor accounts for co-morbidity patterns among unipolar mood and anxiety disorders, whereas a latent externalizing factor underlies the covariation of substance-use disorders and antisocial behaviors. However, this structure needs to be extended to include a broader range of disorders.
  
  
  METHODS
  Exploratory and confirmatory factor analyses were used to examine the structure of co-morbidity using data from the Collaborative Psychiatric Epidemiological Surveys (n = 16 233).
  
  
  RESULTS
  In the best-fitting model, eating and bipolar disorders formed subfactors within internalizing, impulse control disorders were indicators of externalizing, and factor-analytically derived personality disorder scales split between internalizing and externalizing.
  
  
  CONCLUSIONS
  This was the first large-scale nationally representative study that has included uncommon mental disorders with sufficient power to examine their fit within a structural model of psychopathology. The results of this study have important implications for conceptualizing myriad mental disorders.
authors.affiliation: Purdue University, Department of Psychological Sciences, West Lafayette, IN 47907, USA.
authors.forename: K T
authors.initials: KT
authors.lastname: Forbush
authors.forename: D
authors.initials: D
authors.lastname: Watson
mesh_terms: D000328:Adult; D001714:Bipolar Disorder / Q000523:psychology; D015897:Comorbidity; D007174:Disruptive, Impulse Control, and Conduct Disorders / Q000523:psychology; D001068:Feeding and Eating Disorders / Q000523:psychology; D005260:Female; D006306:Health Surveys; D006801:Humans; D007389:Internal-External Control; D008297:Male; D001523:Mental Disorders / Q000145:classification / Q000523:psychology*; D008875:Middle Aged; D008960:Models, Psychological; D010554:Personality Disorders / Q000523:psychology; D055815:Young Adult