title: Determinants of quality of life in HIV-infected patients receiving highly active antiretroviral treatment at a medical college ART center in Kolkata, India.
abstract: Health-related quality of life (QOL) has become a high priority of long-term management of HIV-infected individuals. The newly diagnosed HIV cases were assessed to obtain sociodemographic and clinical findings. Eyesenk Personality Questionnaire (EPQ), World Health Organization Quality of Life Brief (WHOQOL-BREF) for HIV-infected patients, and Beck Depression Inventory (BDI) were used to get data regarding personality traits, QOL, and depression scores. A total of 175 patients were included in the study, 128 (73.1%) men and 47 (26.9%) women. Overall 56% of patients screened positive for depression. Presence of depression and high neuroticism score in the personality profile of HIV-infected patients are significantly associated with poorer QOL. High neuroticism score was a strong predictor of poorer QOL in psychological and spiritual domain. Management of HIV-infected patients therefore needs to address these psychological issues.
authors.affiliation: Department of Medicine, Medical College, Kolkata, India.
authors.forename: Arunansu
authors.initials: A
authors.lastname: Talukdar
authors.forename: Malay Kumar
authors.initials: MK
authors.lastname: Ghosal
authors.forename: Debasish
authors.initials: D
authors.lastname: Sanyal
authors.forename: Payel Sengupta
authors.initials: PS
authors.lastname: Talukdar
authors.forename: Prathama
authors.initials: P
authors.lastname: Guha
authors.forename: Subhasis Kamal
authors.initials: SK
authors.lastname: Guha
authors.forename: Saugata
authors.initials: S
authors.lastname: Basu
mesh_terms: D000328:Adult; D023241:Antiretroviral Therapy, Highly Active; D001008:Anxiety Disorders / Q000453:epidemiology; D003863:Depression / Q000175:diagnosis / Q000453:epidemiology; D005260:Female; D015658:HIV Infections / Q000188:drug therapy / Q000523:psychology*; D006801:Humans; D007194:India; D008297:Male; D000075384:Neuroticism; D010044:Outpatient Clinics, Hospital; D011788:Quality of Life