title: Treatment rationale for dogs poisoned with aldicarb (carbamate pesticide).
abstract: The treatment rationale for dogs poisoned by aldicarb is reviewed from a pharmacological perspective. The illegal use of aldicarb to maliciously poison dogs is a major problem in some parts of the world. In South Africa, it is probably the most common canine poisoning treated by companion animal veterinarians. Aldicarb poisoning is an emergency and veterinarians need to be able to diagnose it and start with effective treatment immediately to ensure a reasonable prognosis. Successful treatment depends on the timely use of an anti-muscarinic drug (e.g. atropine). Additional supportive treatment options, including fluid therapy, diphenhydramine, benzodiazepines and the prevention of further absorption (activated charcoal) should also be considered. Possible complications after treatment are also briefly discussed.
authors.affiliation: Outpatients Clinic, Onderstepoort Veterinary Academic Hospital, Department of Companion Animal Clinical Studies, Faculty of Veterinary Science, University of Pretoria, Private Bag X04, Onderstepoort, 0110, South Africa.
authors.forename: L F
authors.initials: LF
authors.lastname: Arnot
authors.forename: D J H
authors.initials: DJ
authors.lastname: Veale
authors.forename: J C A
authors.initials: JC
authors.lastname: Steyl
authors.forename: J G
authors.initials: JG
authors.lastname: Myburgh
mesh_terms: D000448:Aldicarb / Q000506:poisoning*; D000818:Animals; D001285:Atropine / Q000627:therapeutic use; D004283:Dog Diseases / Q000175:diagnosis / Q000628:therapy*; D004285:Dogs; D005440:Fluid Therapy / Q000662:veterinary; D007306:Insecticides / Q000506:poisoning*; D018727:Muscarinic Antagonists / Q000627:therapeutic use; D011041:Poisoning / Q000175:diagnosis / Q000628:therapy / Q000662:veterinary*
chemical_list: D007306:Insecticides; D018727:Muscarinic Antagonists; D001285:Atropine; D000448:Aldicarb