title: First estimates of influenza vaccine effectiveness among severe influenza cases, France, 2011/12.
abstract: Following a suspected virus-vaccine mismatch, the screening method was used to estimate in almost real time the influenza vaccine effectiveness (VE) against severe cases in high-risk individuals. Data on vaccination status were provided by the influenza severe surveillance system and data on vaccination coverage by the National Social Security Scheme. The analysis showed a decline of the vaccine effectiveness in 2011/12 (VE: 30% (95% CI: 22-39)) compared to 2010/11 (VE: 53% (95% CI: 40-67)).
authors.affiliation: Département des maladies infectieuses, Institut de veille sanitaire, Saint-Maurice, France. i.bonmarin@invs.sante.fr
authors.forename: I
authors.initials: I
authors.lastname: Bonmarin
authors.forename: E
authors.initials: E
authors.lastname: Belchior
authors.forename: Y
authors.initials: Y
authors.lastname: Le Strat
authors.forename: D
authors.initials: D
authors.lastname: Levy-Bruhl
mesh_terms: D000368:Aged; D004196:Disease Outbreaks / Q000517:prevention & control* / Q000706:statistics & numerical data; D005260:Female; D005602:France / Q000453:epidemiology; D006801:Humans; D053122:Influenza A Virus, H3N2 Subtype / Q000302:isolation & purification*; D007252:Influenza Vaccines / Q000008:administration & dosage*; D007251:Influenza, Human / Q000453:epidemiology / Q000517:prevention & control* / Q000821:virology; D007362:Intensive Care Units; D008297:Male; D015397:Program Evaluation; D012307:Risk Factors; D012621:Seasons; D018571:Sentinel Surveillance; D014611:Vaccination / Q000706:statistics & numerical data
chemical_list: D007252:Influenza Vaccines