title: Impact of anemia on in-hospital, one-month and one-year mortality in patients with acute coronary syndrome from the Middle East.
abstract: OBJECTIVE
  The aim of this study was to evaluate the impact of admission anemia on in-hospital, one-month, and one-year mortality in patients from the Middle East with acute coronary syndrome (ACS).
  
  
  METHODS
  Data were analyzed from 7922 consecutive patients admitted to hospitals throughout six Middle-Eastern countries with the final diagnosis of ACS, as part of Gulf RACE II (Registry of Acute Coronary Events II). Anemia at admission was defined according to the World Health Organization definition (<13 g/dL in men and <12 g/dL in women). Analyses were conducted using univariate and multivariate statistical techniques.
  
  
  RESULTS
  The median age of the cohort was 56 (48-65) years, with the majority being male (79%). Anemia at admission was present in 2241 patients (28%). Patients with anemia were more likely to have in-hospital complications including heart failure, recurrent ischemia, re-infarction, cardiogenic shock, stroke, and major bleed. Even after adjustment, anemia was still associated with mortality at in-hospital (odds ratio [OR]=1.71, 95% confidence interval [CI], 1.34-2.17; P<0.001), at one-month (OR=1.34, 95% CI, 1.06-1.71; P=0.016), and at one-year (OR=1.22, 95% CI, 1.01-1.49; P=0.049) post-admission with ACS.
  
  
  CONCLUSIONS
  Admission anemia in patients with ACS from six Middle-Eastern countries was strongly associated with mortality at in-hospital, one-month, and at one-year. Hence, admission anemia must be considered in the initial risk assessment of ACS patients along with other risk scores.
authors.affiliation: Department of Cardiology, Royal Hospital, PO Box 1331, Muscat PC-111, Sultanate of Oman. kjsulaiman@hotmail.com
authors.forename: Kadhim
authors.initials: K
authors.lastname: Sulaiman
authors.forename: Panduranga
authors.initials: P
authors.lastname: Prashanth
authors.forename: Ibrahim
authors.initials: I
authors.lastname: Al-Zakwani
authors.forename: Wael
authors.initials: W
authors.lastname: Al-Mahmeed
authors.forename: Ahmed
authors.initials: A
authors.lastname: Al-Motarreb
authors.forename: Jassim
authors.initials: J
authors.lastname: Al Suwaidi
authors.forename: Haitham
authors.initials: H
authors.lastname: Amin
authors.forename: Nidal
authors.initials: N
authors.lastname: Asaad
authors.forename: Ahmad
authors.initials: A
authors.lastname: Hersi
authors.forename: Hussam
authors.initials: H
authors.lastname: Al Faleh
authors.forename: Shukri
authors.initials: S
authors.lastname: Al Saif
authors.forename: Alawi A
authors.initials: AA
authors.lastname: Alsheikh-Ali
authors.forename: Jawad
authors.initials: J
authors.lastname: Al Lawati
authors.forename: Khalid
authors.initials: K
authors.lastname: Al-Habib
mesh_terms: D054058:Acute Coronary Syndrome / Q000150:complications* / Q000401:mortality*; D000368:Aged; D000740:Anemia / Q000150:complications* / Q000401:mortality*; D015331:Cohort Studies; D005260:Female; D005500:Follow-Up Studies; D006333:Heart Failure / Q000150:complications; D006454:Hemoglobins / Q000032:analysis; D017052:Hospital Mortality; D006801:Humans; D008297:Male; D008875:Middle Aged; D008877:Middle East / Q000453:epidemiology; D009203:Myocardial Infarction / Q000150:complications; D012008:Recurrence; D012189:Retrospective Studies; D018570:Risk Assessment; D012307:Risk Factors; D012770:Shock, Cardiogenic / Q000150:complications; D020521:Stroke / Q000150:complications
chemical_list: D006454:Hemoglobins