title: In vivo imaging of the diseased nervous system: an update.
abstract: Cellular in vivo imaging can reveal the induction, progression and resolution of nervous system pathology in real-time. In this review, we summarize recent research in the field to illustrate how in vivo imaging has enhanced our understanding of a variety of neurological conditions caused by trauma, degeneration, ischemia or inflammation. Finally, we look ahead and discuss how novel biosensors might help us to follow not only the cellular but also the molecular pathogenesis of neurological diseases in vivo.
authors.affiliation: Institute of Clinical Neuroimmunology, Klinikum der Universität München, Marchioninistr. 17, 81377 Munich. martin.kerschensteiner@med.uni-muenchen.de.
authors.forename: Catherine
authors.initials: C
authors.lastname: Sorbara
authors.forename: Thomas
authors.initials: T
authors.lastname: Misgeld
authors.forename: Martin
authors.initials: M
authors.lastname: Kerschensteiner
mesh_terms: D000818:Animals; D015374:Biosensing Techniques / Q000379:methods* / Q000639:trends; D002545:Brain Ischemia / Q000175:diagnosis / Q000503:physiopathology; D003952:Diagnostic Imaging / Q000379:methods* / Q000639:trends; D018450:Disease Progression; D006801:Humans; D007249:Inflammation / Q000175:diagnosis / Q000503:physiopathology; D057054:Molecular Imaging / Q000379:methods / Q000639:trends; D009422:Nervous System Diseases / Q000175:diagnosis* / Q000503:physiopathology; D019636:Neurodegenerative Diseases / Q000175:diagnosis / Q000503:physiopathology; D020196:Trauma, Nervous System / Q000175:diagnosis / Q000503:physiopathology