title: Skull vault destruction after rhinocerebral mucormycosis.
abstract: BACKGROUND
  Mucormycosis is a relatively rare form of fungal infection that can be rapidly progressive. Clinical presentation depends on the anatomic area of involvement; however, the commonest form is that of rhinocerebral.
  
  
  METHODS
  This is the first case of extensive and progressive destruction of the skull vault despite antifungal therapy. The patient required aggressive surgical resection to arrest the disease progression and complex reconstruction using a custom made titanium cranioplasty.
  
  
  CONCLUSIONS
  This report highlights the need for early aggressive resection for cases of mucormycosis infection where there is bony involvement.
authors.affiliation: Department of Neurosurgery, Sir Charles Gairdner Hospital, Nedlands and Royal Perth Hospital, Perth, Western Australia, Australia. stephen.honeybul@health.wa.gov.au
authors.forename: Stephen
authors.initials: S
authors.lastname: Honeybul
authors.forename: David Anthony
authors.initials: DA
authors.lastname: Morrison
mesh_terms: D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009091:Mucormycosis / Q000473:pathology* / Q000601:surgery; D010000:Osteitis / Q000382:microbiology* / Q000473:pathology* / Q000601:surgery; D019651:Plastic Surgery Procedures; D012886:Skull / Q000382:microbiology* / Q000473:pathology* / Q000601:surgery; D014057:Tomography, X-Ray Computed