title: A Validation Study of the Japanese Version of the Addenbrooke's Cognitive Examination-Revised.
abstract: The aim of this study was to validate the Japanese version of the Addenbrooke's Cognitive Examination-Revised (ACE-R) [Mori: Japanese Edition of Hodges JR's Cognitive Assessment for Clinicians, 2010] designed to detect dementia, and to compare its diagnostic accuracy with that of the Mini-Mental State Examination. The ACE-R was administered to 85 healthy individuals and 126 patients with dementia. The reliability assessment revealed a strong correlation in both groups. The internal consistency was excellent (α-coefficient = 0.88). Correlation with the Clinical Dementia Rating sum of boxes score was significant (r(s) = -0.61, p < 0.001). The area under the curve was 0.98 for the ACE-R and 0.96 for the Mini-Mental State Examination. The cut-off score of 80 showed a sensitivity of 94% and a specificity of 94%. Like the original ACE-R and the versions designed for other languages, the Japanese version of the ACE-R is a reliable and valid test for the detection of dementia.
authors.affiliation: Department of Behavioral Neurology and Cognitive Neuroscience, Tohoku University Graduate School of Medicine, Sendai, Japan.
authors.forename: Kelssy Hitomi
authors.initials: KH
authors.lastname: Dos Santos Kawata
authors.forename: Ryusaku
authors.initials: R
authors.lastname: Hashimoto
authors.forename: Yoshiyuki
authors.initials: Y
authors.lastname: Nishio
authors.forename: Atsuko
authors.initials: A
authors.lastname: Hayashi
authors.forename: Nanayo
authors.initials: N
authors.lastname: Ogawa
authors.forename: Shigenori
authors.initials: S
authors.lastname: Kanno
authors.forename: Kotaro
authors.initials: K
authors.lastname: Hiraoka
authors.forename: Kayoko
authors.initials: K
authors.lastname: Yokoi
authors.forename: Osamu
authors.initials: O
authors.lastname: Iizuka
authors.forename: Etsuro
authors.initials: E
authors.lastname: Mori