title: Exstrophy polyp is a unique pathology entity.
abstract: Classic bladder exstrophy is a rare congenital malformation occurring with an incidence of about 1 in 50 000 live births. Polypoid lesions frequently arise in the exstrophic bladder template; this has been well described in the pediatric urological literature. These lesions, however, are not as familiar to pathologists and oftentimes constitute diagnostic challenges. Careful observation revealed that these polyps are unique in their histopathologic appearance, with deep penetrating nests of urothelium or cysts and surrounding concentric fibrosis. Combining the unique clinical setting, a separate pathologic and diagnostic entity should be initiated for this type of polyp; we propose the term 'bladder exstrophy polyp' or simply an 'exstrophy polyp.'
authors.affiliation:   Department of Pathology, Indiana University School of Medicine, Indianapolis, IN, USA. fanr@iupui.edu
authors.forename: Rong
authors.initials: R
authors.lastname: Fan
authors.forename: David J
authors.initials: DJ
authors.lastname: Grignon
authors.forename: Audrey
authors.initials: A
authors.lastname: Rhee
authors.forename: Kristen K
authors.initials: KK
authors.lastname: Meldrum
authors.forename: Liang
authors.initials: L
authors.lastname: Cheng
mesh_terms: D000293:Adolescent; D001746:Bladder Exstrophy / Q000150:complications / Q000473:pathology*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D011127:Polyps / Q000209:etiology / Q000473:pathology*; D001749:Urinary Bladder Neoplasms / Q000209:etiology / Q000473:pathology*