title: Genetic reassortment between Sathuperi and Shamonda viruses of the genus Orthobunyavirus in nature: implications for their genetic relationship to Schmallenberg virus.
abstract: The recent outbreak of malformations in ruminants in Northern Europe caused by Schmallenberg virus induced us to analyze the genetic properties of the related orthobunyaviruses and clarify their relationship. The sequencing of three genomic RNA segments of Sathuperi, Shamonda and Douglas viruses (SATV, SHAV and DOUV) revealed that the M RNA segment of SATV and DOUV had a high degree of sequence identity with that of Schmallenberg virus, but the S and L RNA segments closely matched those of SHAV. Phylogenetic analysis of the three genomic RNA segments indicated that Schmallenberg virus is a reassortant, with the M RNA segment from SATV and the S and L RNA segments from SHAV.
authors.affiliation: Kyushu Research Station, National Institute of Animal Health, NARO, 2702, Chuzan, Kagoshima 891-0105, Japan. tyanase@affrc.go.jp
authors.forename: Tohru
authors.initials: T
authors.lastname: Yanase
authors.forename: Tomoko
authors.initials: T
authors.lastname: Kato
authors.forename: Maki
authors.initials: M
authors.lastname: Aizawa
authors.forename: Yozo
authors.initials: Y
authors.lastname: Shuto
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Shirafuji
authors.forename: Makoto
authors.initials: M
authors.lastname: Yamakawa
authors.forename: Tomoyuki
authors.initials: T
authors.lastname: Tsuda
mesh_terms: D000818:Animals; D002044:Bunyaviridae Infections / Q000662:veterinary / Q000821:virology; D002417:Cattle; D002418:Cattle Diseases / Q000821:virology; D002519:Ceratopogonidae / Q000821:virology; D016851:Orthobunyavirus / Q000145:classification* / Q000235:genetics*; D010802:Phylogeny; D012367:RNA, Viral / Q000032:analysis / Q000235:genetics; D016865:Reassortant Viruses / Q000235:genetics*; D011995:Recombination, Genetic; D017423:Sequence Analysis, RNA
chemical_list: D012367:RNA, Viral