title: Evaluation of fungal-specific fluorescent labeled echinocandin probes as diagnostic adjuncts.
abstract: The diagnosis of invasive fungal infections from radiographic imaging is non-specific and problematic. As a first step toward increasing specificity, we describe the development of a broad-spectrum fungal-specific targeting molecule, which when modified with a fluorescent label fully retains its targeting properties, and provides a basis for future imaging applications.
authors.affiliation: Public Health Research Institute, New Jersey Medical School - UMDNJ ,  Newark, New Jersey 07103 ,  USA.
authors.forename: Ayiasha
authors.initials: A
authors.lastname: Pratt
authors.forename: Guillermo
authors.initials: G
authors.lastname: Garcia-Effron
authors.forename: Yanan
authors.initials: Y
authors.lastname: Zhao
authors.forename: Steven
authors.initials: S
authors.lastname: Park
authors.forename: Arkady
authors.initials: A
authors.lastname: Mustaev
authors.forename: Shyamala
authors.initials: S
authors.lastname: Pillai
authors.forename: David S
authors.initials: DS
authors.lastname: Perlin
mesh_terms: D000935:Antifungal Agents / Q000138:chemical synthesis / Q000737:chemistry; D001232:Aspergillus fumigatus / Q000302:isolation & purification; D002176:Candida albicans / Q000302:isolation & purification; D054714:Echinocandins / Q000138:chemical synthesis / Q000737:chemistry; D005456:Fluorescent Dyes / Q000138:chemical synthesis / Q000737:chemistry; D005658:Fungi / Q000302:isolation & purification*; D009181:Mycoses / Q000175:diagnosis* / Q000382:microbiology; D013045:Species Specificity
chemical_list: D000935:Antifungal Agents; D054714:Echinocandins; D005456:Fluorescent Dyes