title: Comparison of the quick mild cognitive impairment (Qmci) screen and the SMMSE in screening for mild cognitive impairment.
abstract: BACKGROUND
  differentiating mild cognitive impairment (MCI) from normal cognition (NC) is difficult. The AB Cognitive Screen (ABCS) 135, sensitive in differentiating MCI from dementia, was modified to improve sensitivity and specificity, producing the quick mild cognitive impairment (Qmci) screen.
  
  
  OBJECTIVE
  this study compared the sensitivity and specificity of the Qmci with the Standardised MMSE and ABCS 135, to differentiate NC, MCI and dementia.
  
  
  METHODS
  weightings and subtests of the ABCS 135 were changed and a new section 'logical memory' added, creating the Qmci. From four memory clinics in Ontario, Canada, 335 subjects (154 with MCI, 181 with dementia) were recruited and underwent comprehensive assessment. Caregivers, attending with the subjects, without cognitive symptoms, were recruited as controls (n = 630).
  
  
  RESULTS
  the Qmci was more sensitive than the SMMSE and ABCS 135, in differentiating MCI from NC, with an area under the curve (AUC) of 0.86 compared with 0.67 and 0.83, respectively, and in differentiating MCI from mild dementia, AUC of 0.92 versus 0.91 and 0.91. The ability of the Qmci to identify MCI was better for those over 75 years.
  
  
  CONCLUSIONS
  the Qmci is more sensitive than the SMMSE in differentiating MCI and NC, making it a useful test, for MCI in clinical practice, especially for older adults.
authors.affiliation: Department of Gerontology and Rehabilitation,  St Finbarrs Hospital, Douglas Road, Cork City,  Ireland.
authors.forename: Rónán
authors.initials: R
authors.lastname: O'Caoimh
authors.forename: Yang
authors.initials: Y
authors.lastname: Gao
authors.forename: Ciara
authors.initials: C
authors.lastname: McGlade
authors.forename: Liam
authors.initials: L
authors.lastname: Healy
authors.forename: Paul
authors.initials: P
authors.lastname: Gallagher
authors.forename: Suzanne
authors.initials: S
authors.lastname: Timmons
authors.forename: D William
authors.initials: DW
authors.lastname: Molloy
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003071:Cognition / Q000502:physiology; D060825:Cognitive Dysfunction / Q000175:diagnosis* / Q000503:physiopathology / Q000523:psychology; D005260:Female; D006801:Humans; D007361:Intelligence Tests; D008297:Male; D008403:Mass Screening / Q000379:methods*; D008875:Middle Aged; D009864:Ontario; D012189:Retrospective Studies; D012680:Sensitivity and Specificity