title: Occurrence and antimicrobial susceptibility of Porphyromonas spp. and Fusobacterium spp. in dogs with and without periodontitis.
abstract: The occurrence of Porphyromonas gulae, Porphyromonas macacae, Fusobacterium nucleatum and Fusobacterium canifelinum in subgingival plaque from dogs with and without periodontitis as well as their antimicrobial susceptibility were evaluated. From 50 dogs with periodontitis were identified 38 P. gulae, 8 P. macacae, 26 F. nucleatum and 15 F. canifelinum, and from 50 dogs without periodontitis were identified 15 P. gulae, 12 F. nucleatum and 11 F. canifelinum. All strains were susceptible to most of the antibiotics tested, however, different resistance rates to clarithromycin, erythromycin and metronidazole among strains were observed. The role of P. gulae, P. macacae, F. nucleatum and F. canifelinum in periodontal disease of household pets needs to be defined to a better prevention and treatment of the canine periodontitis.
authors.affiliation: Anaerobe Laboratory, Department of Microbiology, Institute of Biomedical Science, University of São Paulo, Brazil.
authors.forename: Gerusa N A
authors.initials: GN
authors.lastname: Senhorinho
authors.forename: Viviane
authors.initials: V
authors.lastname: Nakano
authors.forename: Chengxu
authors.initials: C
authors.lastname: Liu
authors.forename: Yuli
authors.initials: Y
authors.lastname: Song
authors.forename: Sydney M
authors.initials: SM
authors.lastname: Finegold
authors.forename: Mario J
authors.initials: MJ
authors.lastname: Avila-Campos
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D016866:Bacteroidaceae Infections / Q000382:microbiology; D017291:Clarithromycin / Q000494:pharmacology; D003773:Dental Plaque / Q000382:microbiology; D004283:Dog Diseases / Q000382:microbiology*; D004285:Dogs / Q000382:microbiology*; D024881:Drug Resistance, Bacterial; D004917:Erythromycin / Q000494:pharmacology; D005260:Female; D005673:Fusobacterium / Q000187:drug effects* / Q000302:isolation & purification* / Q000378:metabolism; D005674:Fusobacterium Infections / Q000382:microbiology; D006385:Hemagglutination Inhibition Tests; D006801:Humans; D008297:Male; D008795:Metronidazole / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D010518:Periodontitis / Q000382:microbiology*; D017861:Porphyromonas / Q000187:drug effects* / Q000302:isolation & purification* / Q000378:metabolism
chemical_list: D000900:Anti-Bacterial Agents; D008795:Metronidazole; D004917:Erythromycin; D017291:Clarithromycin