title: SIEDY scale 3, a new instrument to detect psychological component in subjects with erectile dysfunction.
abstract: BACKGROUND
  We previously developed and validated a structured interview (SIEDY) dealing with the organic (Scale 1), relational (Scale 2), and psychological (Scale 3) components of erectile dysfunction (ED).
  
  
  OBJECTIVE
  To identify a pathological threshold for SIEDY Scale 3 and to analyze Scale 3 score with biological and psychological correlates in subjects with sexual dysfunction.
  
  
  METHODS
  A pathological threshold of SIEDY Scale 3 score in predicting subjects with a medical history of psychopathology and using psychiatric drugs was identified through receiver operating characteristic (ROC) curve analysis in a sample of 484 patients (Sample A).
  
  
  METHODS
  Sensitivity and specificity, along with possible interactions with biological and psychological (Middlesex Hospital Questionnaire, MHQ-score) correlates were verified in a further sample of 1,275 patients (Sample B).
  
  
  RESULTS
  In sample A, 39 (8%) and 60 (12.4%) subjects reported a positive medical history for psychiatric disturbances or for the use of psychotropic medication, respectively. The association with both conditions was present in 28 (5.8%) subjects. ROC curve showed that SIEDY Scale 3 score predicts psychopathology with an accuracy of 69.5 ± 5.9% (P<0.002), when a threshold of 3 was chosen. When the same threshold was applied in Sample B, it identified a higher ranking in MHQ-A (free-floating anxiety), MHQ-S (somatized anxiety) and MHQ-D (depressive symptoms) subscales, even after adjustment for age and Σ-MHQ (a broader index of general psychopathology). In the same sample, we also confirmed that pathological Scale 3 score was related to a higher risk of psychopathology at medical history or to the use of psychotropic drugs as well as with risky lifestyle behaviors, including smoking and alcohol abuse, and elevated BMI.
  
  
  CONCLUSIONS
  SIEDY represents an easy tool for the identification of patients with a relevant intra-psychic component who should be considered for psychological/psychiatric treatment.
authors.affiliation: Andrology and Sexual Medicine Unit, Department of Clinical Physiopathology, University of Florence, Florence Italy.
authors.forename: Giovanni
authors.initials: G
authors.lastname: Corona
authors.forename: Valdo
authors.initials: V
authors.lastname: Ricca
authors.forename: Elisa
authors.initials: E
authors.lastname: Bandini
authors.forename: Giulia
authors.initials: G
authors.lastname: Rastrelli
authors.forename: Helen
authors.initials: H
authors.lastname: Casale
authors.forename: Emmanuele A
authors.initials: EA
authors.lastname: Jannini
authors.forename: Alessandra
authors.initials: A
authors.lastname: Sforza
authors.forename: Gianni
authors.initials: G
authors.lastname: Forti
authors.forename: Edoardo
authors.initials: E
authors.lastname: Mannucci
authors.forename: Mario
authors.initials: M
authors.lastname: Maggi
mesh_terms: D000328:Adult; D001007:Anxiety / Q000175:diagnosis / Q000503:physiopathology; D003863:Depression / Q000175:diagnosis / Q000503:physiopathology; D007172:Erectile Dysfunction / Q000175:diagnosis / Q000503:physiopathology / Q000523:psychology*; D005260:Female; D006801:Humans; D008019:Life Style; D008297:Male; D001523:Mental Disorders / Q000175:diagnosis* / Q000503:physiopathology; D008875:Middle Aged; D011581:Psychological Tests; D012680:Sensitivity and Specificity; D011795:Surveys and Questionnaires