title: Solid organ donation in a child after extracorporeal membrane oxygenation, orthotopic heart transplantation, and ventricular assist device support.
abstract: Use of high-risk or marginal donors is the most viable short-term means to boost the organ supply and bridge the widening gap between the number of patients on the waiting list for organ transplantation and the insufficient numbers of organ donors. Expansion of the donor pool requires an understanding of the impact on survival likely to result from extending one or more high risk factors. Use of extended donor pool results in shorter waiting list times and limits the morbidity and mortality associated with long-term mechanical support needed to support diseased organs. In this report, we present one such example of expanding donor pool in which a pediatric patient donated a solid organ after two heart transplants and successful use of ECMO and VAD.
authors.affiliation: Division of Pediatric Cardiology, Department of Pediatrics, University of Arkansas Medical Center, Little Rock, Arkansas, USA. pgupta2@uams.edu
authors.forename: Punkaj
authors.initials: P
authors.lastname: Gupta
authors.forename: Carlos
authors.initials: C
authors.lastname: Blanco
authors.forename: Melissa
authors.initials: M
authors.lastname: Madigan
authors.forename: Andrew
authors.initials: A
authors.lastname: Dodgen
authors.forename: Mari
authors.initials: M
authors.lastname: Hanson
authors.forename: Elizabeth A
authors.initials: EA
authors.lastname: Frazier
authors.forename: Adnan T
authors.initials: AT
authors.lastname: Bhutta
authors.forename: William P
authors.initials: WP
authors.lastname: Fiser
mesh_terms: D000368:Aged; D002648:Child; D015199:Extracorporeal Membrane Oxygenation / Q000379:methods*; D017809:Fatal Outcome; D005260:Female; D006085:Graft Survival; D006333:Heart Failure / Q000628:therapy; D016027:Heart Transplantation / Q000379:methods*; D006353:Heart-Assist Devices / Q000009:adverse effects*; D006801:Humans; D016031:Liver Transplantation / Q000379:methods; D016377:Organ Transplantation; D010100:Oxygen / Q000737:chemistry*; D011664:Pulmonary Valve / Q000473:pathology; D012086:Reoperation; D012307:Risk Factors; D013771:Tetralogy of Fallot / Q000628:therapy; D016896:Treatment Outcome
chemical_list: D010100:Oxygen