title: Bicyclic C21 terpenoids from the marine sponge Clathria compressa.
abstract: Three new bicyclic C(21) terpenoids, clathric acid (1) and two N-acyl taurine derivatives, clathrimides A (2) and B (3), were isolated from the marine sponge Clathria compressa. The structures of these compounds were elucidated by interpretation of spectroscopic data. Clathric acid showed mild antibacterial activity against several Gram-positive bacteria.
authors.affiliation: Department of Chemistry and Biochemistry, Florida Atlantic University, Boca Raton, Florida 33431, USA.
authors.forename: Prasoon
authors.initials: P
authors.lastname: Gupta
authors.forename: Upasana
authors.initials: U
authors.lastname: Sharma
authors.forename: Thomas C
authors.initials: TC
authors.lastname: Schulz
authors.forename: Amanda B
authors.initials: AB
authors.lastname: McLean
authors.forename: Allan J
authors.initials: AJ
authors.lastname: Robins
authors.forename: Lyndon M
authors.initials: LM
authors.lastname: West
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006094:Gram-Positive Bacteria / Q000187:drug effects; D008386:Marine Biology; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D009792:Oceans and Seas; D011161:Porifera / Q000737:chemistry*; D013729:Terpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D013729:Terpenes; C575039:clathric acid; C575040:clathrimide A; C575041:clathrimide B