title: Early recurrence or submucosal residual of laryngeal squamous cell carcinoma: diagnosis by CT-guided endolaryngeal core biopsy on a transcutaneous approach.
abstract: BACKGROUND
  Ultrasound and CT-guided biopsy is a common procedure for histologic diagnosis of recurrence of head and neck squamous cell carcinoma. The present study describes a novel CT-guided endolaryngeal puncture site.
  
  
  RESULTS
  A 59-year-old man was treated for a T2N0M0 supraglottic laryngeal tumor by laser resection and bilateral lymph node dissection; exeresis was judged complete. Six-month follow-up found persistent dysphonia. Endoscopic examination and iterative biopsy gave reassuring results, but (18) fluorodeoxyglucose positron emission tomography-CT ((18) FDG PET-CT) found highly suspicious increased right hemilaryngeal metabolic activity. Diagnosis of residual tumor was confirmed on CT-guided endolaryngeal biopsy.
  
  
  CONCLUSIONS
  Image-guided biopsy is the technique of choice in head and neck lesions that are deep or difficult to palpate and inaccessible to endoscopy. It is especially useful when recurrence is suspected after radiation therapy or cancer surgery. Many puncture sites have been reported in the literature; the present novel laryngeal approach extends the range of image-guided biopsy, although further studies will be needed to assess possible morbidity.
authors.affiliation: Department of Radiology, Clermont Tonnerre Military Hospital, Brest, France. jean.rousset29@wanadoo.fr
authors.forename: Jean
authors.initials: J
authors.lastname: Rousset
authors.forename: Ronan
authors.initials: R
authors.lastname: Abgral
authors.forename: Sandra
authors.initials: S
authors.lastname: Chinellato
authors.forename: Marc
authors.initials: M
authors.lastname: Garetier
authors.forename: Céline
authors.initials: C
authors.lastname: Barberot
authors.forename: Gérald
authors.initials: G
authors.lastname: Valette
authors.forename: Gaël
authors.initials: G
authors.lastname: Potard
authors.forename: Thierry
authors.initials: T
authors.lastname: Le Bivic
authors.forename: Pierre-Yves
authors.initials: PY
authors.lastname: Salaun
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000175:diagnosis* / Q000000981:diagnostic imaging; D019788:Fluorodeoxyglucose F18; D006801:Humans; D007822:Laryngeal Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging; D007830:Larynx / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis* / Q000000981:diagnostic imaging; D018365:Neoplasm, Residual / Q000175:diagnosis* / Q000000981:diagnostic imaging; D049268:Positron-Emission Tomography / Q000379:methods; D019275:Radiopharmaceuticals; D015899:Tomography, Emission-Computed, Single-Photon; D014057:Tomography, X-Ray Computed / Q000379:methods*
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18