title: Spectral-domain optical coherence tomography of astrocytic hamartomas in tuberous sclerosis.
abstract: Retinal astrocytic hamartomas are benign tumors of the retinal nerve fiber layer (NFL) that may be found in association with tuberous sclerosis (TS). We describe the spectral-domain optical coherence tomography (SD-OCT) features of type 1 astrocytic hamartomas in a child with TS that may aid in the diagnosis and follow-up of these lesions. Gradual, dome-shaped hyper-reflective elevations of the retinal NFL were seen on SD-OCT with subtle shadowing of the underlying tissues. In addition, the vitreous cortex showed focal adhesions to the surface of the tumor.
authors.affiliation: Guru Nanak Eye Centre, Maulana Azad Medical College, New Delhi, India. nehadoc@hotmail.com
authors.forename: Neha
authors.initials: N
authors.lastname: Goel
authors.forename: Bhanu
authors.initials: B
authors.lastname: Pangtey
authors.forename: Gauri
authors.initials: G
authors.lastname: Bhushan
authors.forename: Usha Kaul
authors.initials: UK
authors.lastname: Raina
authors.forename: Basudeb
authors.initials: B
authors.lastname: Ghosh
mesh_terms: D001253:Astrocytes / Q000473:pathology*; D002648:Child; D003937:Diagnosis, Differential; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D006222:Hamartoma / Q000150:complications / Q000473:pathology*; D006801:Humans; D008297:Male; D012160:Retina / Q000473:pathology*; D012164:Retinal Diseases / Q000150:complications / Q000473:pathology*; D041623:Tomography, Optical Coherence / Q000379:methods*; D014402:Tuberous Sclerosis / Q000150:complications*; D014792:Visual Acuity