title: Predicting need for allogeneic transfusion after total knee arthroplasty.
abstract: Total knee arthroplasty (TKA) can lead to substantial blood loss. To avoid the high costs of autologous blood predonation programs and efficiently allocate limited blood resources, we sought to identify preoperative and intraoperative factors associated with allogeneic blood transfusion (AllTx) after primary TKA and, subsequently, develop a model to predict patients who will require AllTx. We analyzed 31 independent variables in 644 primary unilateral TKAs without autologous blood predonation for requirement of AllTx. Seventy-one procedures (11.0%) required AllTx. Age, comorbid anemia, preoperative hemoglobin concentration, and surgical time were significant predictors for requiring AllTx. When applied to an independent cohort, our model for predicting the need for AllTx after TKA was 90% sensitive and 52.5% specific.
authors.affiliation: Center for Hip and Knee Replacement (CHKR), NewYork-Presbyterian Hospital at Columbia University, New York, New York 10032, USA.
authors.forename: Manish S
authors.initials: MS
authors.lastname: Noticewala
authors.forename: Jonathan D
authors.initials: JD
authors.lastname: Nyce
authors.forename: Wenbao
authors.initials: W
authors.lastname: Wang
authors.forename: Jeffrey A
authors.initials: JA
authors.lastname: Geller
authors.forename: William
authors.initials: W
authors.lastname: Macaulay
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000740:Anemia / Q000453:epidemiology; D019645:Arthroplasty, Replacement, Knee / Q000706:statistics & numerical data*; D016063:Blood Loss, Surgical / Q000706:statistics & numerical data*; D001803:Blood Transfusion / Q000706:statistics & numerical data*; D015331:Cohort Studies; D015897:Comorbidity; D005260:Female; D006454:Hemoglobins / Q000378:metabolism; D006801:Humans; D008297:Male; D008875:Middle Aged; D015233:Models, Statistical; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D013997:Time Factors; D055815:Young Adult
chemical_list: D006454:Hemoglobins