title: Isolated corneal pseudodendrites as the initial manifestation of tyrosinemia type II in monozygotic twins.
abstract: Fifteen-month-old twins presented with photophobia and bilateral corneal pseudodendrites, and tyrosinemia type II was suspected. Plasma tyrosine levels were elevated. After therapy with tyrosine-restricted diet, corneal lesions resolved. Bilateral pseudodendritic keratitis may be the initial or only manifestation of tyrosinemia type II.
authors.affiliation: University of Crete, School of Health Sciences, Thessaloniki, Greece. kymionis@med.uoc.gr
authors.forename: George D
authors.initials: GD
authors.lastname: Kymionis
authors.forename: Vardhaman P
authors.initials: VP
authors.lastname: Kankariya
authors.forename: Georgios A
authors.initials: GA
authors.lastname: Kontadakis
authors.forename: Nikolas G
authors.initials: NG
authors.lastname: Ziakas
mesh_terms: D001764:Blepharospasm / Q000175:diagnosis; D003316:Corneal Diseases / Q000175:diagnosis* / Q000178:diet therapy / Q000235:genetics; D003712:Dendrites / Q000473:pathology*; D018753:Diet, Protein-Restricted; D004200:Diseases in Twins / Q000175:diagnosis* / Q000178:diet therapy / Q000235:genetics; D006801:Humans; D007223:Infant; D008297:Male; D020795:Photophobia / Q000175:diagnosis; D014430:Twins, Monozygotic; D014443:Tyrosine / Q000097:blood; D020176:Tyrosinemias / Q000175:diagnosis* / Q000178:diet therapy / Q000235:genetics
chemical_list: D014443:Tyrosine