title: Velamo do campo: its volatile constituents, secretory elements, and biological activity.
abstract: The volatile components from Croton campestris root bark were localized by an anatomical study and analyzed by gas chromatography-mass spectrometry for the first time. The roots of this plant showed secretory cells. These volatile constituents, isolated from the dichloromethane extract by hydrodistillation, were analyzed by gas chromatography-mass spectrometry. We found 69 components. They were characterized, and the major constituents of crude oil root barks were spathulenol (23.3%) and borneol (18.7%). Growth inhibitory activity of the active compounds in solution was evaluated by measuring minimal inhibitory concentrations using a broth micromethod. The minimal inhibitory concentration of root bark volatile constituents was 1.56 μg/mL for Staphylococcus aureus, 3.125 μg/mL for Candida albicans, and 6.25 μg/mL for Aspergillusniger.
authors.affiliation: Laboratory of Botanic Mycology (UMR 5623 35), Virology and Industrial Microbiology, Faculty of Pharmaceutical Sciences, University Paul Sabatier Toulouse III, Toulouse, France. elbabili@cict.fr
authors.forename: Fatiha
authors.initials: F
authors.lastname: El Babili
authors.forename: Christine
authors.initials: C
authors.lastname: Roques
authors.forename: Laila
authors.initials: L
authors.lastname: Haddioui
authors.forename: Floriant
authors.initials: F
authors.lastname: Bellvert
authors.forename: Cédric
authors.initials: C
authors.lastname: Bertrand
authors.forename: Christian
authors.initials: C
authors.lastname: Chatelain
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D000935:Antifungal Agents / Q000494:pharmacology; D001234:Aspergillus niger / Q000187:drug effects*; D001892:Camphanes / Q000032:analysis / Q000494:pharmacology; D002176:Candida albicans / Q000187:drug effects*; D029802:Croton / Q000737:chemistry*; D008826:Microbial Sensitivity Tests; D009822:Oils, Volatile / Q000032:analysis / Q000494:pharmacology*; D024301:Plant Bark; D059828:Plant Cells; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology*; D018517:Plant Roots; D012717:Sesquiterpenes / Q000032:analysis / Q000494:pharmacology; D013211:Staphylococcus aureus / Q000187:drug effects*; D055549:Volatile Organic Compounds / Q000032:analysis / Q000494:pharmacology*
chemical_list: D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D001892:Camphanes; D009822:Oils, Volatile; D010936:Plant Extracts; D012717:Sesquiterpenes; D055549:Volatile Organic Compounds; C013258:spathulenol; C022871:isoborneol