title: Rosuvastatin-induced pemphigoid.
abstract: Statins are widely prescribed medications and very well tolerated. Rosuvastatin is another member of this drug used to treat dyslipidaemia. It is a competitive inhibitor of the enzyme 3-hydroxy-3-methylglutaryl coenzyme A reductase. Immunobullous disease is usually idiopathic but can be drug-induced. Both idiopathic and iatrogenic forms share common clinical and immunohistological features. The authors report a case of pemphigoid induced by rosuvastatin, a commonly prescribed medication. To our knowledge, there is limited report on rosuvastatin associated with pemphigoid in the literature.
authors.affiliation: Dermatology Department, Adelaide and Meath Hospital, Dublin, Ireland. aiz100@hotmail.com
authors.forename: Aizuri A
authors.initials: AA
authors.lastname: Murad
authors.forename: Maureen
authors.initials: M
authors.lastname: Connolly
authors.forename: Anne-Marie
authors.initials: AM
authors.lastname: Tobin
mesh_terms: D001706:Biopsy; D050171:Dyslipidemias / Q000188:drug therapy*; D005260:Female; D005455:Fluorescent Antibody Technique; D005464:Fluorobenzenes / Q000009:adverse effects*; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000009:adverse effects*; D008875:Middle Aged; D010391:Pemphigoid, Bullous / Q000139:chemically induced*; D011743:Pyrimidines / Q000009:adverse effects*; D000068718:Rosuvastatin Calcium; D013449:Sulfonamides / Q000009:adverse effects*
chemical_list: D005464:Fluorobenzenes; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D011743:Pyrimidines; D013449:Sulfonamides; D000068718:Rosuvastatin Calcium