title: Endogenous thyroid-stimulating hormone and radioactive iodine uptake in normal subjects.
abstract: In 105 normal volunteers, 52 male and 53 female, mean age 45 (range, 20-68), serum thyroid-stimulating hormone (TSH) (1.46 ± 0.7; range, 0.43-3.87 microUI/mL) and 24-hour thyroid radioactive iodine uptake (RAIU) (16.15% ± 4.78% range, 6.45%-30.08%) were measured. Additionally, TSH was 1.18 ± 0.5 microUI/mL for 20 to 29 year-olds and 1.59 ± 0.9 microUI/mL for 60 to 68 year old (P = 0.037). RAIU was 18.30 ± 4.5 for 20 to 29-year-olds and 14.92 ± 3.1 for 60 to 68 year-olds (P = 0.009). TSH trends positively and RAIU at 24 hours correlates negatively with aging of the pituitary axis.
authors.affiliation: Sección Medicina Nuclear, Departamento de Medicina, Hospital Clínico de la Universidad de Chile, Santiago, Chile. pgonzalez@redclinicauchile.cl
authors.forename: Patricio
authors.initials: P
authors.lastname: González
authors.forename: Rodrigo
authors.initials: R
authors.lastname: Jaimovich
authors.forename: Verónica
authors.initials: V
authors.lastname: Araya
authors.forename: Teresa
authors.initials: T
authors.lastname: Massardo
authors.forename: Alberto
authors.initials: A
authors.lastname: Carmona
mesh_terms: D000328:Adult; D000368:Aged; D000375:Aging / Q000097:blood / Q000378:metabolism; D001692:Biological Transport; D001774:Blood Chemical Analysis / Q000592:standards*; D005260:Female; D006801:Humans; D007457:Iodine Radioisotopes / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D012016:Reference Values; D013972:Thyrotropin / Q000097:blood*; D055815:Young Adult
chemical_list: D007457:Iodine Radioisotopes; D013972:Thyrotropin