title: Filgrastim as a rescue therapy for persistent neutropenia in a case of dengue hemorrhagic Fever with acute respiratory distress syndrome and myocarditis.
abstract: Pathogenesis of dengue involves suppression of immune system leading to development of characteristic presentation of haematological picture of thrombocytopenia and leucopenia. Sometimes, this suppression in immune response is responsible for deterioration in clinical status of the patient in spite of all specific and supportive therapy. Certain drugs like steroids are used for rescue therapy in conditions like sepsis. We present a novel use of filgrastim as a rescue therapy in a patient with dengue hemorrhagic fever (DHF) with acute respiratory distress syndrome (ARDS), myocarditis, and febrile neutropenia and not responding to standard management.
authors.affiliation: Department of Anaesthesiology and Intensive Care, Postgraduate Institute of Medical Education and Research and Dr Ram Manohar Lohia Hospital, New Delhi 10041, India.
authors.forename: Desh
authors.initials: D
authors.lastname: Deepak
authors.forename: Rakesh
authors.initials: R
authors.lastname: Garg
authors.forename: Mridula
authors.initials: M
authors.lastname: Pawar
authors.forename: Neerja
authors.initials: N
authors.lastname: Banerjee
authors.forename: Rakesh
authors.initials: R
authors.lastname: Solanki
authors.forename: Indubala
authors.initials: I
authors.lastname: Maurya