title: Prevalence, clinical manifestations and endoscopic features of eosinophilic esophagitis: a pathological review in China.
abstract: OBJECTIVE
  We aimed to determine the prevalence of eosinophilic esophagitis (EoE) and define its clinical and endoscopic characteristics in Chinese patients.
  
  
  METHODS
  Esophageal specimens obtained from January 2006 to December 2010 in the First Affiliated Hospital of Sun Yat-sen University were reviewed, and the data on clinical characteristics and endoscopic findings of patients were obtained. Patients with eosinophils ≥15 per high power field (HPF) were identified as having EoE.
  
  
  RESULTS
  A total of 12 patients met the criteria for EoE, establishing a prevalence of 0.34%. These patients presented with dysphagia (4/12, 33.3%), gastroesophageal reflux disease (GERD)-like symptoms (3/12, 25.0%), abdominal pain (3/12, 25.0%) and others (2/12, 16.7%). The most common endoscopic finding was plaques (5/12, 41.7%), and other findings were irregular Z-line (2/12, 16.7%), erosive esophagitis (2/12, 16.7%), white exudates (1/12, 8.3%), linear furrows (1/12, 8.3%), Schatzki ring (1/12, 8.3%), ulcers (1/12, 8.3%) and erythema (1/12, 8.3%).
  
  
  CONCLUSIONS
  The prevalence of EoE was 0.34% in our patients. Clinicians should pay attention to patients manifested with dysphagia and GERD-like symptomes with endosopic findings of white exudates, plaques, Schatzki ring and linear furrows.
authors.affiliation: Department of Internal Medicine, Guro Hospital, Korea University College of Medicine, Seoul, Korea.
authors.forename: Yi Nan
authors.initials: YN
authors.lastname: Shi
authors.forename: Shi Jun
authors.initials: SJ
authors.lastname: Sun
authors.forename: Li Shou
authors.initials: LS
authors.lastname: Xiong
authors.forename: Qing Hua
authors.initials: QH
authors.lastname: Cao
authors.forename: Yi
authors.initials: Y
authors.lastname: Cui
authors.forename: Min Hu
authors.initials: MH
authors.lastname: Chen
mesh_terms: D000328:Adult; D000368:Aged; D001706:Biopsy; D002681:China / Q000453:epidemiology; D003680:Deglutition Disorders / Q000453:epidemiology / Q000209:etiology; D057765:Eosinophilic Esophagitis / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology* / Q000628:therapy; D004945:Esophagoscopy; D004947:Esophagus / Q000473:pathology; D005260:Female; D005764:Gastroesophageal Reflux / Q000453:epidemiology / Q000209:etiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence