title: [Renal affection in gout].
abstract: The study of the problem of impairment of the kidneys in gout is important because investigation of gout nephropathy specifies the role of hyperuricemia (a known risk factor) in development of renal damage, on the one side, and emphasizes the role of early detection of hyperuricemic genesis of nephropathy allowing prognosis improvement due to administration of uricostatic treatment, on the other side. Earlier data on tubulointerstitial lesion are now supplied with information on essential glomerular damage due to endothelial dysfunction in the presence of insulin resistance often associated with gout.
authors.forename: I V
authors.initials: IV
authors.lastname: Egorov
authors.forename: V V
authors.initials: VV
authors.lastname: Tsurko
mesh_terms: D003404:Creatinine / Q000378:metabolism; D006073:Gout / Q000150:complications / Q000378:metabolism / Q000503:physiopathology; D006801:Humans; D033461:Hyperuricemia / Q000209:etiology / Q000378:metabolism; D007333:Insulin Resistance; D007674:Kidney Diseases / Q000209:etiology / Q000378:metabolism / Q000473:pathology / Q000503:physiopathology; D007678:Kidney Glomerulus / Q000378:metabolism / Q000473:pathology / Q000503:physiopathology; D011379:Prognosis; D014527:Uric Acid / Q000378:metabolism; D014528:Uricosuric Agents / Q000627:therapeutic use*
chemical_list: D014528:Uricosuric Agents; D014527:Uric Acid; D003404:Creatinine