title: Anxiety symptoms in patients with frontal lobe epilepsy versus generalized epilepsy.
abstract: OBJECTIVE
  The aim of this study was to compare the frequency of anxiety symptoms between patients with frontal lobe epilepsy (FLE) and generalized epilepsy (GE).
  
  
  METHODS
  Forty and 78 patients with FLE and GE respectively were enrolled in the study. Anxiety symptoms were measured with the Hamilton anxiety rating scale (HARS) and the anxiety subscale of the hospital anxiety and depression scale (HADSA).
  
  
  RESULTS
  Compared to the GE group, the FLE group had significantly higher HARS (10.9±8.7 vs. 7.9±6.8, p=0.039) scores. Significant correlations were also found between anxiety symptoms and epilepsy-related variables, particularly with the seizure frequency and the number of currently taken anti-epileptic drugs.
  
  
  CONCLUSIONS
  Anxiety symptoms are more common in patients with FLE in comparison to those with GE. Further studies are warranted to clarify the relationship between anxiety symptoms and FLE.
authors.affiliation: Department of Psychiatry, Shatin Hospital, Chinese University of Hong Kong, Shatin, N.T., Hong Kong, China. tangwk@cuhk.edu.hk
authors.forename: W K
authors.initials: WK
authors.lastname: Tang
authors.forename: Jinyan
authors.initials: J
authors.lastname: Lu
authors.forename: Gabor S
authors.initials: GS
authors.lastname: Ungvari
authors.forename: K S
authors.initials: KS
authors.lastname: Wong
authors.forename: Patrick
authors.initials: P
authors.lastname: Kwan
mesh_terms: D000328:Adult; D001007:Anxiety / Q000453:epidemiology*; D017034:Epilepsy, Frontal Lobe / Q000523:psychology*; D004829:Epilepsy, Generalized / Q000523:psychology*; D005260:Female; D006801:Humans; D008297:Male