title: Synthetic mesh in the surgical repair of pelvic organ prolapse: current status and future directions.
abstract: In light of the recent Food and Drug Administration public health notification regarding complications associated with transvaginally placed mesh for pelvic organ prolapse (POP) repair, we review recent literature to evaluate current outcomes and complication data, analyze the clinical need for mesh on the basis of genetic and biochemical etiologies of POP, and investigate trends of mesh use via an American Urological Association member survey. Mesh-based techniques show better anatomic results than traditional repair of anterior POP, but subjective outcomes are equivalent. Further research and Level I evidence are required before mesh-based repair of POP can be standardized. Adequate surgical training and patient selection should decrease complication rates.
authors.affiliation: Department of Urology, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.
authors.forename: Tristan
authors.initials: T
authors.lastname: Keys
authors.forename: Lysanne
authors.initials: L
authors.lastname: Campeau
authors.forename: Gopal
authors.initials: G
authors.lastname: Badlani
mesh_terms: D005260:Female; D005544:Forecasting; D006801:Humans; D015201:Meta-Analysis as Topic; D056887:Pelvic Organ Prolapse / Q000453:epidemiology / Q000601:surgery*; D016032:Randomized Controlled Trials as Topic; D013526:Surgical Mesh / Q000009:adverse effects / Q000639:trends