title: [Effect of Carisolv on endodontic microleakage].
abstract: OBJECTIVE
  To evaluate the effect of Carisolv on endodontic microleakage by establishing a fluid transport model using sodium nitrite as tracer.
  
  
  METHODS
  Seventy extracted teeth were randomly divided into 5 groups, all the root canals were prepared with different chemical reagents, including Carisolv,3% hydrogen peroxide+ 2%tosylchloramide sodium,2.5% sodium hypochlorite,5% sodium hypochlorite(negative control)and distilled water(positive control),post spaces were prepared after cold lateral condensation, the samples were put on the model, concentration of sodium nitrite which penetrated from the coronal to the apical end was measured by diazo reaction at 1,2,4,7,10,15,20,25,30,35,40,45,50,55 and 60 day. The data were analyzed by ANOVA using SPSS 11.5 software package.
  
  
  RESULTS
  Sodium nitrite was not detected in negative control group from 1 day to 60 days. High concentration of sodium nitrite was detected in positive control group at first day, concentration of sodium nitrite was higher than that of other four groups from 1day to 60 days(P<0.01). Concentration of sodium nitrite in Carisolv group was significantly lower than that of 3%hydrogen peroxide+ 2% tosylchloramide sodium group(P<0.01), also lower than that of 2.5% sodium hypochlorite group(P<0.05),except at 25,30,35 and 40 days.
  
  
  CONCLUSIONS
  Carisolv can remove the smear layer, decrease the endodontic microleakage, seal the root canal better. The fluid transport model using sodium nitrite as tracer can be used to evaluate the endodontic microleakage objectively,sensitively and exactly.
authors.affiliation: Department of Endodontics, China Medical University, Shenyang, China. shaolina8238@yahoo.com.cn
authors.forename: Li-na
authors.initials: LN
authors.lastname: Shao
authors.forename: Fu-liang
authors.initials: FL
authors.lastname: Zhan
authors.forename: Li-hong
authors.initials: LH
authors.lastname: Qiu
authors.forename: Ming
authors.initials: M
authors.lastname: Zhong
mesh_terms: D003786:Dental Pulp Cavity; D018698:Glutamic Acid; D006801:Humans; D007930:Leucine; D008239:Lysine; D011897:Random Allocation; D012388:Root Canal Irrigants; D012390:Root Canal Therapy; D016369:Smear Layer; D012973:Sodium Hypochlorite
chemical_list: C119934:Carisolv; D012388:Root Canal Irrigants; D018698:Glutamic Acid; D012973:Sodium Hypochlorite; D007930:Leucine; D008239:Lysine