title: Computational structural analysis of protein interactions and networks.
abstract: Protein interactions have been at the focus of computational biology in recent years. In particular, interest has come from two different communities--structural and systems biology. Here, we will discuss key systems and structural biology methods that have been used for analysis and prediction of protein-protein interactions and the insight these approaches have provided on the nature and organization of protein-protein interactions inside cells.
authors.affiliation: Terrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, Canada.
authors.forename: Yogesh
authors.initials: Y
authors.lastname: Hooda
authors.forename: Philip M
authors.initials: PM
authors.lastname: Kim
mesh_terms: D000818:Animals; D001185:Artificial Intelligence; D019295:Computational Biology / Q000379:methods*; D006801:Humans; D051379:Mice; D008958:Models, Molecular; D011487:Protein Conformation; D025941:Protein Interaction Mapping / Q000379:methods*; D060066:Protein Interaction Maps; D011506:Proteins / Q000737:chemistry* / Q000378:metabolism*
chemical_list: D011506:Proteins