title: Cutaneous drug eruptions associated with the use of biologies and cutaneous drug eruptions mimicking specific skin diseases.
abstract: Drug eruptions are common adverse events affecting approximately 3% of hospitalized patients, and can be seen with the use of almost any medication. Making a diagnosis could be challenging because no pattern is specific for a particular drug. A study of clinical aspects, histopathology and history of drug intake is usually necessary to establish the diagnosis, and discontinue the offending agent when feasible. The pathomechanisms of drug-related skin reactions remain unclear. However, the induction of drug reactions by a new class of biologies which block a specific target should help to better understand the pathogenesis of these eruptions.
authors.affiliation: Department of Dermatology, Saint-André Hospital, Bordeaux University, Bordeaux, France. julien.seneschal@chu-bordeaux.fr
authors.forename: Julien
authors.initials: J
authors.lastname: Seneschal
authors.forename: Brigitte
authors.initials: B
authors.lastname: Milpied
authors.forename: Alain
authors.initials: A
authors.lastname: Taieb
mesh_terms: D000152:Acne Vulgaris / Q000175:diagnosis / Q000209:etiology; D003875:Drug Eruptions / Q000175:diagnosis* / Q000209:etiology; D064420:Drug-Related Side Effects and Adverse Reactions; D006201:Hair Diseases / Q000175:diagnosis / Q000209:etiology; D006801:Humans; D008178:Lupus Erythematosus, Cutaneous / Q000175:diagnosis / Q000209:etiology; D008180:Lupus Erythematosus, Systemic / Q000175:diagnosis / Q000209:etiology; D011565:Psoriasis / Q000473:pathology; D012871:Skin Diseases / Q000175:diagnosis* / Q000209:etiology; D012872:Skin Diseases, Vesiculobullous / Q000175:diagnosis / Q000209:etiology; D012880:Skin Pigmentation; D014657:Vasculitis / Q000175:diagnosis / Q000209:etiology